data_9GSZ
# 
_entry.id   9GSZ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GSZ         pdb_00009gsz 10.2210/pdb9gsz/pdb 
WWPDB D_1292141821 ?            ?                   
EMDB  EMD-51559    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-05-21 ? 
2 'EM metadata'     1 0 2025-05-21 ? 
3 FSC               1 0 2025-05-21 ? 
4 'Half map'        1 0 2025-05-21 1 
5 'Half map'        1 0 2025-05-21 2 
6 Image             1 0 2025-05-21 ? 
7 'Primary map'     1 0 2025-05-21 ? 
8 'Structure model' 1 1 2025-06-11 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 8 'Structure model' 'Data collection'     
2 8 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 8 'Structure model' citation        
2 8 'Structure model' citation_author 
3 8 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  8 'Structure model' '_citation.country'                 
2  8 'Structure model' '_citation.journal_abbrev'          
3  8 'Structure model' '_citation.journal_id_CSD'          
4  8 'Structure model' '_citation.journal_id_ISSN'         
5  8 'Structure model' '_citation.journal_volume'          
6  8 'Structure model' '_citation.page_first'              
7  8 'Structure model' '_citation.page_last'               
8  8 'Structure model' '_citation.pdbx_database_id_DOI'    
9  8 'Structure model' '_citation.pdbx_database_id_PubMed' 
10 8 'Structure model' '_citation.title'                   
11 8 'Structure model' '_citation.year'                    
12 8 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GSZ 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB MCT8-T4                                         EMD-50523 'consensus EM volume'  
PDB  MCT8-T4                                         9FKN      unspecified            
EMDB MCT8                                            EMD-51311 'consensus EM volume'  
PDB  MCT8                                            9GF8      unspecified            
EMDB MCT8-silychristin                               EMD-50629 'consensus EM volume'  
PDB  MCT8-silychristin                               9FOT      unspecified            
EMDB 'Human monocarboxylate 10 bound to L-thyroxine' EMD-51559 'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              francesca.coscia@fht.org 
_pdbx_contact_author.name_first         Francesca 
_pdbx_contact_author.name_last          Coscia 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7962-303X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Coscia, F.'    1 0000-0001-7962-303X 
'Tassinari, M.' 2 0000-0001-6423-4891 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                4493 
_citation.page_last                 4493 
_citation.title                     'Molecular mechanism of thyroxine transport by monocarboxylate transporters.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-59751-w 
_citation.pdbx_database_id_PubMed   40368961 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Tassinari, M.'   1  ?                   
primary 'Tanzi, G.'       2  0000-0002-3500-0559 
primary 'Maggiore, F.'    3  0009-0008-8629-2687 
primary 'Groeneweg, S.'   4  ?                   
primary 'van Geest, F.S.' 5  0000-0002-6960-5775 
primary 'Freund, M.E.T.'  6  0009-0007-0757-8939 
primary 'Stavast, C.J.'   7  0000-0003-1460-3112 
primary 'Boniardi, I.'    8  0009-0005-0951-2402 
primary 'Pasqualato, S.'  9  0000-0002-9038-7768 
primary 'Visser, W.E.'    10 0000-0002-5248-863X 
primary 'Coscia, F.'      11 0000-0001-7962-303X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Monocarboxylate transporter 10'  53242.465 1 ? ? ? ? 
2 non-polymer syn "3,5,3',5'-TETRAIODO-L-THYRONINE" 776.870   1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
'MCT 10,Aromatic amino acid transporter 1,Solute carrier family 16 member 10,T-type amino acid transporter 1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MDYKDDDDKMVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPPEGGWGW
LVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAV
GFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLF
YTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGIPLALFGYFVPY
VHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLI
MGLFDGCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPS
RLEEELRRRLTEP
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MDYKDDDDKMVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPPEGGWGW
LVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAV
GFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLF
YTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGIPLALFGYFVPY
VHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLI
MGLFDGCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPS
RLEEELRRRLTEP
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        "3,5,3',5'-TETRAIODO-L-THYRONINE" 
_pdbx_entity_nonpoly.comp_id     T44 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   TYR n 
1 4   LYS n 
1 5   ASP n 
1 6   ASP n 
1 7   ASP n 
1 8   ASP n 
1 9   LYS n 
1 10  MET n 
1 11  VAL n 
1 12  LEU n 
1 13  SER n 
1 14  GLN n 
1 15  GLU n 
1 16  GLU n 
1 17  PRO n 
1 18  ASP n 
1 19  SER n 
1 20  ALA n 
1 21  ARG n 
1 22  GLY n 
1 23  THR n 
1 24  SER n 
1 25  GLU n 
1 26  ALA n 
1 27  GLN n 
1 28  PRO n 
1 29  LEU n 
1 30  GLY n 
1 31  PRO n 
1 32  ALA n 
1 33  PRO n 
1 34  THR n 
1 35  GLY n 
1 36  ALA n 
1 37  ALA n 
1 38  PRO n 
1 39  PRO n 
1 40  PRO n 
1 41  GLY n 
1 42  PRO n 
1 43  GLY n 
1 44  PRO n 
1 45  SER n 
1 46  ASP n 
1 47  SER n 
1 48  PRO n 
1 49  GLU n 
1 50  ALA n 
1 51  ALA n 
1 52  VAL n 
1 53  GLU n 
1 54  LYS n 
1 55  VAL n 
1 56  GLU n 
1 57  VAL n 
1 58  GLU n 
1 59  LEU n 
1 60  ALA n 
1 61  GLY n 
1 62  PRO n 
1 63  ALA n 
1 64  THR n 
1 65  ALA n 
1 66  GLU n 
1 67  PRO n 
1 68  HIS n 
1 69  GLU n 
1 70  PRO n 
1 71  PRO n 
1 72  GLU n 
1 73  PRO n 
1 74  PRO n 
1 75  GLU n 
1 76  GLY n 
1 77  GLY n 
1 78  TRP n 
1 79  GLY n 
1 80  TRP n 
1 81  LEU n 
1 82  VAL n 
1 83  MET n 
1 84  LEU n 
1 85  ALA n 
1 86  ALA n 
1 87  MET n 
1 88  TRP n 
1 89  CYS n 
1 90  ASN n 
1 91  GLY n 
1 92  SER n 
1 93  VAL n 
1 94  PHE n 
1 95  GLY n 
1 96  ILE n 
1 97  GLN n 
1 98  ASN n 
1 99  ALA n 
1 100 CYS n 
1 101 GLY n 
1 102 VAL n 
1 103 LEU n 
1 104 PHE n 
1 105 VAL n 
1 106 SER n 
1 107 MET n 
1 108 LEU n 
1 109 GLU n 
1 110 THR n 
1 111 PHE n 
1 112 GLY n 
1 113 SER n 
1 114 LYS n 
1 115 ASP n 
1 116 ASP n 
1 117 ASP n 
1 118 LYS n 
1 119 MET n 
1 120 VAL n 
1 121 PHE n 
1 122 LYS n 
1 123 THR n 
1 124 ALA n 
1 125 TRP n 
1 126 VAL n 
1 127 GLY n 
1 128 SER n 
1 129 LEU n 
1 130 SER n 
1 131 MET n 
1 132 GLY n 
1 133 MET n 
1 134 ILE n 
1 135 PHE n 
1 136 PHE n 
1 137 CYS n 
1 138 CYS n 
1 139 PRO n 
1 140 ILE n 
1 141 VAL n 
1 142 SER n 
1 143 VAL n 
1 144 PHE n 
1 145 THR n 
1 146 ASP n 
1 147 LEU n 
1 148 PHE n 
1 149 GLY n 
1 150 CYS n 
1 151 ARG n 
1 152 LYS n 
1 153 THR n 
1 154 ALA n 
1 155 VAL n 
1 156 VAL n 
1 157 GLY n 
1 158 ALA n 
1 159 ALA n 
1 160 VAL n 
1 161 GLY n 
1 162 PHE n 
1 163 VAL n 
1 164 GLY n 
1 165 LEU n 
1 166 MET n 
1 167 SER n 
1 168 SER n 
1 169 SER n 
1 170 PHE n 
1 171 VAL n 
1 172 SER n 
1 173 SER n 
1 174 ILE n 
1 175 GLU n 
1 176 PRO n 
1 177 LEU n 
1 178 TYR n 
1 179 LEU n 
1 180 THR n 
1 181 TYR n 
1 182 GLY n 
1 183 ILE n 
1 184 ILE n 
1 185 PHE n 
1 186 ALA n 
1 187 CYS n 
1 188 GLY n 
1 189 CYS n 
1 190 SER n 
1 191 PHE n 
1 192 ALA n 
1 193 TYR n 
1 194 GLN n 
1 195 PRO n 
1 196 SER n 
1 197 LEU n 
1 198 VAL n 
1 199 ILE n 
1 200 LEU n 
1 201 GLY n 
1 202 HIS n 
1 203 TYR n 
1 204 PHE n 
1 205 LYS n 
1 206 LYS n 
1 207 ARG n 
1 208 LEU n 
1 209 GLY n 
1 210 LEU n 
1 211 VAL n 
1 212 ASN n 
1 213 GLY n 
1 214 ILE n 
1 215 VAL n 
1 216 THR n 
1 217 ALA n 
1 218 GLY n 
1 219 SER n 
1 220 SER n 
1 221 VAL n 
1 222 PHE n 
1 223 THR n 
1 224 ILE n 
1 225 LEU n 
1 226 LEU n 
1 227 PRO n 
1 228 LEU n 
1 229 LEU n 
1 230 LEU n 
1 231 ARG n 
1 232 VAL n 
1 233 LEU n 
1 234 ILE n 
1 235 ASP n 
1 236 SER n 
1 237 VAL n 
1 238 GLY n 
1 239 LEU n 
1 240 PHE n 
1 241 TYR n 
1 242 THR n 
1 243 LEU n 
1 244 ARG n 
1 245 VAL n 
1 246 LEU n 
1 247 CYS n 
1 248 ILE n 
1 249 PHE n 
1 250 MET n 
1 251 PHE n 
1 252 VAL n 
1 253 LEU n 
1 254 PHE n 
1 255 LEU n 
1 256 ALA n 
1 257 GLY n 
1 258 PHE n 
1 259 THR n 
1 260 TYR n 
1 261 ARG n 
1 262 PRO n 
1 263 LEU n 
1 264 ALA n 
1 265 THR n 
1 266 SER n 
1 267 THR n 
1 268 LYS n 
1 269 ASP n 
1 270 LYS n 
1 271 GLU n 
1 272 SER n 
1 273 GLY n 
1 274 GLY n 
1 275 SER n 
1 276 GLY n 
1 277 SER n 
1 278 SER n 
1 279 LEU n 
1 280 PHE n 
1 281 SER n 
1 282 ARG n 
1 283 LYS n 
1 284 LYS n 
1 285 PHE n 
1 286 SER n 
1 287 PRO n 
1 288 PRO n 
1 289 LYS n 
1 290 LYS n 
1 291 ILE n 
1 292 PHE n 
1 293 ASN n 
1 294 PHE n 
1 295 ALA n 
1 296 ILE n 
1 297 PHE n 
1 298 LYS n 
1 299 VAL n 
1 300 THR n 
1 301 ALA n 
1 302 TYR n 
1 303 ALA n 
1 304 VAL n 
1 305 TRP n 
1 306 ALA n 
1 307 VAL n 
1 308 GLY n 
1 309 ILE n 
1 310 PRO n 
1 311 LEU n 
1 312 ALA n 
1 313 LEU n 
1 314 PHE n 
1 315 GLY n 
1 316 TYR n 
1 317 PHE n 
1 318 VAL n 
1 319 PRO n 
1 320 TYR n 
1 321 VAL n 
1 322 HIS n 
1 323 LEU n 
1 324 MET n 
1 325 LYS n 
1 326 HIS n 
1 327 VAL n 
1 328 ASN n 
1 329 GLU n 
1 330 ARG n 
1 331 PHE n 
1 332 GLN n 
1 333 ASP n 
1 334 GLU n 
1 335 LYS n 
1 336 ASN n 
1 337 LYS n 
1 338 GLU n 
1 339 VAL n 
1 340 VAL n 
1 341 LEU n 
1 342 MET n 
1 343 CYS n 
1 344 ILE n 
1 345 GLY n 
1 346 VAL n 
1 347 THR n 
1 348 SER n 
1 349 GLY n 
1 350 VAL n 
1 351 GLY n 
1 352 ARG n 
1 353 LEU n 
1 354 LEU n 
1 355 PHE n 
1 356 GLY n 
1 357 ARG n 
1 358 ILE n 
1 359 ALA n 
1 360 ASP n 
1 361 TYR n 
1 362 VAL n 
1 363 PRO n 
1 364 GLY n 
1 365 VAL n 
1 366 LYS n 
1 367 LYS n 
1 368 VAL n 
1 369 TYR n 
1 370 LEU n 
1 371 GLN n 
1 372 VAL n 
1 373 LEU n 
1 374 SER n 
1 375 PHE n 
1 376 PHE n 
1 377 PHE n 
1 378 ILE n 
1 379 GLY n 
1 380 LEU n 
1 381 MET n 
1 382 SER n 
1 383 MET n 
1 384 MET n 
1 385 ILE n 
1 386 PRO n 
1 387 LEU n 
1 388 CYS n 
1 389 SER n 
1 390 ILE n 
1 391 PHE n 
1 392 GLY n 
1 393 ALA n 
1 394 LEU n 
1 395 ILE n 
1 396 ALA n 
1 397 VAL n 
1 398 CYS n 
1 399 LEU n 
1 400 ILE n 
1 401 MET n 
1 402 GLY n 
1 403 LEU n 
1 404 PHE n 
1 405 ASP n 
1 406 GLY n 
1 407 CYS n 
1 408 PHE n 
1 409 ILE n 
1 410 SER n 
1 411 ILE n 
1 412 MET n 
1 413 ALA n 
1 414 PRO n 
1 415 ILE n 
1 416 ALA n 
1 417 PHE n 
1 418 GLU n 
1 419 LEU n 
1 420 VAL n 
1 421 GLY n 
1 422 ALA n 
1 423 GLN n 
1 424 ASP n 
1 425 VAL n 
1 426 SER n 
1 427 GLN n 
1 428 ALA n 
1 429 ILE n 
1 430 GLY n 
1 431 PHE n 
1 432 LEU n 
1 433 LEU n 
1 434 GLY n 
1 435 PHE n 
1 436 MET n 
1 437 SER n 
1 438 ILE n 
1 439 PRO n 
1 440 MET n 
1 441 THR n 
1 442 VAL n 
1 443 GLY n 
1 444 PRO n 
1 445 PRO n 
1 446 ILE n 
1 447 ALA n 
1 448 GLY n 
1 449 LEU n 
1 450 LEU n 
1 451 ARG n 
1 452 ASP n 
1 453 LYS n 
1 454 LEU n 
1 455 GLY n 
1 456 SER n 
1 457 TYR n 
1 458 ASP n 
1 459 VAL n 
1 460 ALA n 
1 461 PHE n 
1 462 TYR n 
1 463 LEU n 
1 464 ALA n 
1 465 GLY n 
1 466 VAL n 
1 467 PRO n 
1 468 PRO n 
1 469 LEU n 
1 470 ILE n 
1 471 GLY n 
1 472 GLY n 
1 473 ALA n 
1 474 VAL n 
1 475 LEU n 
1 476 CYS n 
1 477 PHE n 
1 478 ILE n 
1 479 PRO n 
1 480 SER n 
1 481 ARG n 
1 482 LEU n 
1 483 GLU n 
1 484 GLU n 
1 485 GLU n 
1 486 LEU n 
1 487 ARG n 
1 488 ARG n 
1 489 ARG n 
1 490 LEU n 
1 491 THR n 
1 492 GLU n 
1 493 PRO n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   493 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'SLC16A10, MCT10, TAT1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                           ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                          ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                        ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ? 'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE                          ? 'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE                         ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                           ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                         ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                        ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                           ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                            ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                        ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                     ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                           ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                            ? 'C3 H7 N O3'      105.093 
T44 non-polymer         . "3,5,3',5'-TETRAIODO-L-THYRONINE" ? 'C15 H11 I4 N O4' 776.870 
THR 'L-peptide linking' y THREONINE                         ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                        ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                          ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                            ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -8  ?   ?   ?   A . n 
A 1 2   ASP 2   -7  ?   ?   ?   A . n 
A 1 3   TYR 3   -6  ?   ?   ?   A . n 
A 1 4   LYS 4   -5  ?   ?   ?   A . n 
A 1 5   ASP 5   -4  ?   ?   ?   A . n 
A 1 6   ASP 6   -3  ?   ?   ?   A . n 
A 1 7   ASP 7   -2  ?   ?   ?   A . n 
A 1 8   ASP 8   -1  ?   ?   ?   A . n 
A 1 9   LYS 9   0   ?   ?   ?   A . n 
A 1 10  MET 10  1   ?   ?   ?   A . n 
A 1 11  VAL 11  2   ?   ?   ?   A . n 
A 1 12  LEU 12  3   ?   ?   ?   A . n 
A 1 13  SER 13  4   ?   ?   ?   A . n 
A 1 14  GLN 14  5   ?   ?   ?   A . n 
A 1 15  GLU 15  6   ?   ?   ?   A . n 
A 1 16  GLU 16  7   ?   ?   ?   A . n 
A 1 17  PRO 17  8   ?   ?   ?   A . n 
A 1 18  ASP 18  9   ?   ?   ?   A . n 
A 1 19  SER 19  10  ?   ?   ?   A . n 
A 1 20  ALA 20  11  ?   ?   ?   A . n 
A 1 21  ARG 21  12  ?   ?   ?   A . n 
A 1 22  GLY 22  13  ?   ?   ?   A . n 
A 1 23  THR 23  14  ?   ?   ?   A . n 
A 1 24  SER 24  15  ?   ?   ?   A . n 
A 1 25  GLU 25  16  ?   ?   ?   A . n 
A 1 26  ALA 26  17  ?   ?   ?   A . n 
A 1 27  GLN 27  18  ?   ?   ?   A . n 
A 1 28  PRO 28  19  ?   ?   ?   A . n 
A 1 29  LEU 29  20  ?   ?   ?   A . n 
A 1 30  GLY 30  21  ?   ?   ?   A . n 
A 1 31  PRO 31  22  ?   ?   ?   A . n 
A 1 32  ALA 32  23  ?   ?   ?   A . n 
A 1 33  PRO 33  24  ?   ?   ?   A . n 
A 1 34  THR 34  25  ?   ?   ?   A . n 
A 1 35  GLY 35  26  ?   ?   ?   A . n 
A 1 36  ALA 36  27  ?   ?   ?   A . n 
A 1 37  ALA 37  28  ?   ?   ?   A . n 
A 1 38  PRO 38  29  ?   ?   ?   A . n 
A 1 39  PRO 39  30  ?   ?   ?   A . n 
A 1 40  PRO 40  31  ?   ?   ?   A . n 
A 1 41  GLY 41  32  ?   ?   ?   A . n 
A 1 42  PRO 42  33  ?   ?   ?   A . n 
A 1 43  GLY 43  34  ?   ?   ?   A . n 
A 1 44  PRO 44  35  ?   ?   ?   A . n 
A 1 45  SER 45  36  ?   ?   ?   A . n 
A 1 46  ASP 46  37  ?   ?   ?   A . n 
A 1 47  SER 47  38  ?   ?   ?   A . n 
A 1 48  PRO 48  39  ?   ?   ?   A . n 
A 1 49  GLU 49  40  ?   ?   ?   A . n 
A 1 50  ALA 50  41  ?   ?   ?   A . n 
A 1 51  ALA 51  42  ?   ?   ?   A . n 
A 1 52  VAL 52  43  ?   ?   ?   A . n 
A 1 53  GLU 53  44  ?   ?   ?   A . n 
A 1 54  LYS 54  45  ?   ?   ?   A . n 
A 1 55  VAL 55  46  ?   ?   ?   A . n 
A 1 56  GLU 56  47  ?   ?   ?   A . n 
A 1 57  VAL 57  48  ?   ?   ?   A . n 
A 1 58  GLU 58  49  ?   ?   ?   A . n 
A 1 59  LEU 59  50  ?   ?   ?   A . n 
A 1 60  ALA 60  51  ?   ?   ?   A . n 
A 1 61  GLY 61  52  ?   ?   ?   A . n 
A 1 62  PRO 62  53  ?   ?   ?   A . n 
A 1 63  ALA 63  54  ?   ?   ?   A . n 
A 1 64  THR 64  55  ?   ?   ?   A . n 
A 1 65  ALA 65  56  ?   ?   ?   A . n 
A 1 66  GLU 66  57  ?   ?   ?   A . n 
A 1 67  PRO 67  58  ?   ?   ?   A . n 
A 1 68  HIS 68  59  ?   ?   ?   A . n 
A 1 69  GLU 69  60  ?   ?   ?   A . n 
A 1 70  PRO 70  61  ?   ?   ?   A . n 
A 1 71  PRO 71  62  ?   ?   ?   A . n 
A 1 72  GLU 72  63  ?   ?   ?   A . n 
A 1 73  PRO 73  64  ?   ?   ?   A . n 
A 1 74  PRO 74  65  ?   ?   ?   A . n 
A 1 75  GLU 75  66  ?   ?   ?   A . n 
A 1 76  GLY 76  67  ?   ?   ?   A . n 
A 1 77  GLY 77  68  ?   ?   ?   A . n 
A 1 78  TRP 78  69  69  TRP TRP A . n 
A 1 79  GLY 79  70  70  GLY GLY A . n 
A 1 80  TRP 80  71  71  TRP TRP A . n 
A 1 81  LEU 81  72  72  LEU LEU A . n 
A 1 82  VAL 82  73  73  VAL VAL A . n 
A 1 83  MET 83  74  74  MET MET A . n 
A 1 84  LEU 84  75  75  LEU LEU A . n 
A 1 85  ALA 85  76  76  ALA ALA A . n 
A 1 86  ALA 86  77  77  ALA ALA A . n 
A 1 87  MET 87  78  78  MET MET A . n 
A 1 88  TRP 88  79  79  TRP TRP A . n 
A 1 89  CYS 89  80  80  CYS CYS A . n 
A 1 90  ASN 90  81  81  ASN ASN A . n 
A 1 91  GLY 91  82  82  GLY GLY A . n 
A 1 92  SER 92  83  83  SER SER A . n 
A 1 93  VAL 93  84  84  VAL VAL A . n 
A 1 94  PHE 94  85  85  PHE PHE A . n 
A 1 95  GLY 95  86  86  GLY GLY A . n 
A 1 96  ILE 96  87  87  ILE ILE A . n 
A 1 97  GLN 97  88  88  GLN GLN A . n 
A 1 98  ASN 98  89  89  ASN ASN A . n 
A 1 99  ALA 99  90  90  ALA ALA A . n 
A 1 100 CYS 100 91  91  CYS CYS A . n 
A 1 101 GLY 101 92  92  GLY GLY A . n 
A 1 102 VAL 102 93  93  VAL VAL A . n 
A 1 103 LEU 103 94  94  LEU LEU A . n 
A 1 104 PHE 104 95  95  PHE PHE A . n 
A 1 105 VAL 105 96  96  VAL VAL A . n 
A 1 106 SER 106 97  97  SER SER A . n 
A 1 107 MET 107 98  98  MET MET A . n 
A 1 108 LEU 108 99  99  LEU LEU A . n 
A 1 109 GLU 109 100 100 GLU GLU A . n 
A 1 110 THR 110 101 101 THR THR A . n 
A 1 111 PHE 111 102 102 PHE PHE A . n 
A 1 112 GLY 112 103 103 GLY GLY A . n 
A 1 113 SER 113 104 104 SER SER A . n 
A 1 114 LYS 114 105 ?   ?   ?   A . n 
A 1 115 ASP 115 106 ?   ?   ?   A . n 
A 1 116 ASP 116 107 ?   ?   ?   A . n 
A 1 117 ASP 117 108 108 ASP ASP A . n 
A 1 118 LYS 118 109 109 LYS LYS A . n 
A 1 119 MET 119 110 110 MET MET A . n 
A 1 120 VAL 120 111 111 VAL VAL A . n 
A 1 121 PHE 121 112 112 PHE PHE A . n 
A 1 122 LYS 122 113 113 LYS LYS A . n 
A 1 123 THR 123 114 114 THR THR A . n 
A 1 124 ALA 124 115 115 ALA ALA A . n 
A 1 125 TRP 125 116 116 TRP TRP A . n 
A 1 126 VAL 126 117 117 VAL VAL A . n 
A 1 127 GLY 127 118 118 GLY GLY A . n 
A 1 128 SER 128 119 119 SER SER A . n 
A 1 129 LEU 129 120 120 LEU LEU A . n 
A 1 130 SER 130 121 121 SER SER A . n 
A 1 131 MET 131 122 122 MET MET A . n 
A 1 132 GLY 132 123 123 GLY GLY A . n 
A 1 133 MET 133 124 124 MET MET A . n 
A 1 134 ILE 134 125 125 ILE ILE A . n 
A 1 135 PHE 135 126 126 PHE PHE A . n 
A 1 136 PHE 136 127 127 PHE PHE A . n 
A 1 137 CYS 137 128 128 CYS CYS A . n 
A 1 138 CYS 138 129 129 CYS CYS A . n 
A 1 139 PRO 139 130 130 PRO PRO A . n 
A 1 140 ILE 140 131 131 ILE ILE A . n 
A 1 141 VAL 141 132 132 VAL VAL A . n 
A 1 142 SER 142 133 133 SER SER A . n 
A 1 143 VAL 143 134 134 VAL VAL A . n 
A 1 144 PHE 144 135 135 PHE PHE A . n 
A 1 145 THR 145 136 136 THR THR A . n 
A 1 146 ASP 146 137 137 ASP ASP A . n 
A 1 147 LEU 147 138 138 LEU LEU A . n 
A 1 148 PHE 148 139 139 PHE PHE A . n 
A 1 149 GLY 149 140 140 GLY GLY A . n 
A 1 150 CYS 150 141 141 CYS CYS A . n 
A 1 151 ARG 151 142 142 ARG ARG A . n 
A 1 152 LYS 152 143 143 LYS LYS A . n 
A 1 153 THR 153 144 144 THR THR A . n 
A 1 154 ALA 154 145 145 ALA ALA A . n 
A 1 155 VAL 155 146 146 VAL VAL A . n 
A 1 156 VAL 156 147 147 VAL VAL A . n 
A 1 157 GLY 157 148 148 GLY GLY A . n 
A 1 158 ALA 158 149 149 ALA ALA A . n 
A 1 159 ALA 159 150 150 ALA ALA A . n 
A 1 160 VAL 160 151 151 VAL VAL A . n 
A 1 161 GLY 161 152 152 GLY GLY A . n 
A 1 162 PHE 162 153 153 PHE PHE A . n 
A 1 163 VAL 163 154 154 VAL VAL A . n 
A 1 164 GLY 164 155 155 GLY GLY A . n 
A 1 165 LEU 165 156 156 LEU LEU A . n 
A 1 166 MET 166 157 157 MET MET A . n 
A 1 167 SER 167 158 158 SER SER A . n 
A 1 168 SER 168 159 159 SER SER A . n 
A 1 169 SER 169 160 160 SER SER A . n 
A 1 170 PHE 170 161 161 PHE PHE A . n 
A 1 171 VAL 171 162 162 VAL VAL A . n 
A 1 172 SER 172 163 163 SER SER A . n 
A 1 173 SER 173 164 164 SER SER A . n 
A 1 174 ILE 174 165 165 ILE ILE A . n 
A 1 175 GLU 175 166 166 GLU GLU A . n 
A 1 176 PRO 176 167 167 PRO PRO A . n 
A 1 177 LEU 177 168 168 LEU LEU A . n 
A 1 178 TYR 178 169 169 TYR TYR A . n 
A 1 179 LEU 179 170 170 LEU LEU A . n 
A 1 180 THR 180 171 171 THR THR A . n 
A 1 181 TYR 181 172 172 TYR TYR A . n 
A 1 182 GLY 182 173 173 GLY GLY A . n 
A 1 183 ILE 183 174 174 ILE ILE A . n 
A 1 184 ILE 184 175 175 ILE ILE A . n 
A 1 185 PHE 185 176 176 PHE PHE A . n 
A 1 186 ALA 186 177 177 ALA ALA A . n 
A 1 187 CYS 187 178 178 CYS CYS A . n 
A 1 188 GLY 188 179 179 GLY GLY A . n 
A 1 189 CYS 189 180 180 CYS CYS A . n 
A 1 190 SER 190 181 181 SER SER A . n 
A 1 191 PHE 191 182 182 PHE PHE A . n 
A 1 192 ALA 192 183 183 ALA ALA A . n 
A 1 193 TYR 193 184 184 TYR TYR A . n 
A 1 194 GLN 194 185 185 GLN GLN A . n 
A 1 195 PRO 195 186 186 PRO PRO A . n 
A 1 196 SER 196 187 187 SER SER A . n 
A 1 197 LEU 197 188 188 LEU LEU A . n 
A 1 198 VAL 198 189 189 VAL VAL A . n 
A 1 199 ILE 199 190 190 ILE ILE A . n 
A 1 200 LEU 200 191 191 LEU LEU A . n 
A 1 201 GLY 201 192 192 GLY GLY A . n 
A 1 202 HIS 202 193 193 HIS HIS A . n 
A 1 203 TYR 203 194 194 TYR TYR A . n 
A 1 204 PHE 204 195 195 PHE PHE A . n 
A 1 205 LYS 205 196 196 LYS LYS A . n 
A 1 206 LYS 206 197 197 LYS LYS A . n 
A 1 207 ARG 207 198 198 ARG ARG A . n 
A 1 208 LEU 208 199 199 LEU LEU A . n 
A 1 209 GLY 209 200 200 GLY GLY A . n 
A 1 210 LEU 210 201 201 LEU LEU A . n 
A 1 211 VAL 211 202 202 VAL VAL A . n 
A 1 212 ASN 212 203 203 ASN ASN A . n 
A 1 213 GLY 213 204 204 GLY GLY A . n 
A 1 214 ILE 214 205 205 ILE ILE A . n 
A 1 215 VAL 215 206 206 VAL VAL A . n 
A 1 216 THR 216 207 207 THR THR A . n 
A 1 217 ALA 217 208 208 ALA ALA A . n 
A 1 218 GLY 218 209 209 GLY GLY A . n 
A 1 219 SER 219 210 210 SER SER A . n 
A 1 220 SER 220 211 211 SER SER A . n 
A 1 221 VAL 221 212 212 VAL VAL A . n 
A 1 222 PHE 222 213 213 PHE PHE A . n 
A 1 223 THR 223 214 214 THR THR A . n 
A 1 224 ILE 224 215 215 ILE ILE A . n 
A 1 225 LEU 225 216 216 LEU LEU A . n 
A 1 226 LEU 226 217 217 LEU LEU A . n 
A 1 227 PRO 227 218 218 PRO PRO A . n 
A 1 228 LEU 228 219 219 LEU LEU A . n 
A 1 229 LEU 229 220 220 LEU LEU A . n 
A 1 230 LEU 230 221 221 LEU LEU A . n 
A 1 231 ARG 231 222 222 ARG ARG A . n 
A 1 232 VAL 232 223 223 VAL VAL A . n 
A 1 233 LEU 233 224 224 LEU LEU A . n 
A 1 234 ILE 234 225 225 ILE ILE A . n 
A 1 235 ASP 235 226 226 ASP ASP A . n 
A 1 236 SER 236 227 227 SER SER A . n 
A 1 237 VAL 237 228 228 VAL VAL A . n 
A 1 238 GLY 238 229 229 GLY GLY A . n 
A 1 239 LEU 239 230 230 LEU LEU A . n 
A 1 240 PHE 240 231 231 PHE PHE A . n 
A 1 241 TYR 241 232 232 TYR TYR A . n 
A 1 242 THR 242 233 233 THR THR A . n 
A 1 243 LEU 243 234 234 LEU LEU A . n 
A 1 244 ARG 244 235 235 ARG ARG A . n 
A 1 245 VAL 245 236 236 VAL VAL A . n 
A 1 246 LEU 246 237 237 LEU LEU A . n 
A 1 247 CYS 247 238 238 CYS CYS A . n 
A 1 248 ILE 248 239 239 ILE ILE A . n 
A 1 249 PHE 249 240 240 PHE PHE A . n 
A 1 250 MET 250 241 241 MET MET A . n 
A 1 251 PHE 251 242 242 PHE PHE A . n 
A 1 252 VAL 252 243 243 VAL VAL A . n 
A 1 253 LEU 253 244 244 LEU LEU A . n 
A 1 254 PHE 254 245 245 PHE PHE A . n 
A 1 255 LEU 255 246 246 LEU LEU A . n 
A 1 256 ALA 256 247 247 ALA ALA A . n 
A 1 257 GLY 257 248 248 GLY GLY A . n 
A 1 258 PHE 258 249 249 PHE PHE A . n 
A 1 259 THR 259 250 250 THR THR A . n 
A 1 260 TYR 260 251 251 TYR TYR A . n 
A 1 261 ARG 261 252 252 ARG ARG A . n 
A 1 262 PRO 262 253 253 PRO PRO A . n 
A 1 263 LEU 263 254 254 LEU LEU A . n 
A 1 264 ALA 264 255 ?   ?   ?   A . n 
A 1 265 THR 265 256 ?   ?   ?   A . n 
A 1 266 SER 266 257 ?   ?   ?   A . n 
A 1 267 THR 267 258 ?   ?   ?   A . n 
A 1 268 LYS 268 259 ?   ?   ?   A . n 
A 1 269 ASP 269 260 ?   ?   ?   A . n 
A 1 270 LYS 270 261 ?   ?   ?   A . n 
A 1 271 GLU 271 262 ?   ?   ?   A . n 
A 1 272 SER 272 263 ?   ?   ?   A . n 
A 1 273 GLY 273 264 ?   ?   ?   A . n 
A 1 274 GLY 274 265 ?   ?   ?   A . n 
A 1 275 SER 275 266 ?   ?   ?   A . n 
A 1 276 GLY 276 267 ?   ?   ?   A . n 
A 1 277 SER 277 268 ?   ?   ?   A . n 
A 1 278 SER 278 269 ?   ?   ?   A . n 
A 1 279 LEU 279 270 ?   ?   ?   A . n 
A 1 280 PHE 280 271 ?   ?   ?   A . n 
A 1 281 SER 281 272 ?   ?   ?   A . n 
A 1 282 ARG 282 273 ?   ?   ?   A . n 
A 1 283 LYS 283 274 ?   ?   ?   A . n 
A 1 284 LYS 284 275 ?   ?   ?   A . n 
A 1 285 PHE 285 276 ?   ?   ?   A . n 
A 1 286 SER 286 277 ?   ?   ?   A . n 
A 1 287 PRO 287 278 ?   ?   ?   A . n 
A 1 288 PRO 288 279 ?   ?   ?   A . n 
A 1 289 LYS 289 280 ?   ?   ?   A . n 
A 1 290 LYS 290 281 ?   ?   ?   A . n 
A 1 291 ILE 291 282 ?   ?   ?   A . n 
A 1 292 PHE 292 283 ?   ?   ?   A . n 
A 1 293 ASN 293 284 284 ASN ASN A . n 
A 1 294 PHE 294 285 285 PHE PHE A . n 
A 1 295 ALA 295 286 286 ALA ALA A . n 
A 1 296 ILE 296 287 287 ILE ILE A . n 
A 1 297 PHE 297 288 288 PHE PHE A . n 
A 1 298 LYS 298 289 289 LYS LYS A . n 
A 1 299 VAL 299 290 290 VAL VAL A . n 
A 1 300 THR 300 291 291 THR THR A . n 
A 1 301 ALA 301 292 292 ALA ALA A . n 
A 1 302 TYR 302 293 293 TYR TYR A . n 
A 1 303 ALA 303 294 294 ALA ALA A . n 
A 1 304 VAL 304 295 295 VAL VAL A . n 
A 1 305 TRP 305 296 296 TRP TRP A . n 
A 1 306 ALA 306 297 297 ALA ALA A . n 
A 1 307 VAL 307 298 298 VAL VAL A . n 
A 1 308 GLY 308 299 299 GLY GLY A . n 
A 1 309 ILE 309 300 300 ILE ILE A . n 
A 1 310 PRO 310 301 301 PRO PRO A . n 
A 1 311 LEU 311 302 302 LEU LEU A . n 
A 1 312 ALA 312 303 303 ALA ALA A . n 
A 1 313 LEU 313 304 304 LEU LEU A . n 
A 1 314 PHE 314 305 305 PHE PHE A . n 
A 1 315 GLY 315 306 306 GLY GLY A . n 
A 1 316 TYR 316 307 307 TYR TYR A . n 
A 1 317 PHE 317 308 308 PHE PHE A . n 
A 1 318 VAL 318 309 309 VAL VAL A . n 
A 1 319 PRO 319 310 310 PRO PRO A . n 
A 1 320 TYR 320 311 311 TYR TYR A . n 
A 1 321 VAL 321 312 312 VAL VAL A . n 
A 1 322 HIS 322 313 313 HIS HIS A . n 
A 1 323 LEU 323 314 314 LEU LEU A . n 
A 1 324 MET 324 315 315 MET MET A . n 
A 1 325 LYS 325 316 316 LYS LYS A . n 
A 1 326 HIS 326 317 317 HIS HIS A . n 
A 1 327 VAL 327 318 318 VAL VAL A . n 
A 1 328 ASN 328 319 319 ASN ASN A . n 
A 1 329 GLU 329 320 320 GLU GLU A . n 
A 1 330 ARG 330 321 321 ARG ARG A . n 
A 1 331 PHE 331 322 322 PHE PHE A . n 
A 1 332 GLN 332 323 323 GLN GLN A . n 
A 1 333 ASP 333 324 324 ASP ASP A . n 
A 1 334 GLU 334 325 325 GLU GLU A . n 
A 1 335 LYS 335 326 326 LYS LYS A . n 
A 1 336 ASN 336 327 327 ASN ASN A . n 
A 1 337 LYS 337 328 328 LYS LYS A . n 
A 1 338 GLU 338 329 329 GLU GLU A . n 
A 1 339 VAL 339 330 330 VAL VAL A . n 
A 1 340 VAL 340 331 331 VAL VAL A . n 
A 1 341 LEU 341 332 332 LEU LEU A . n 
A 1 342 MET 342 333 333 MET MET A . n 
A 1 343 CYS 343 334 334 CYS CYS A . n 
A 1 344 ILE 344 335 335 ILE ILE A . n 
A 1 345 GLY 345 336 336 GLY GLY A . n 
A 1 346 VAL 346 337 337 VAL VAL A . n 
A 1 347 THR 347 338 338 THR THR A . n 
A 1 348 SER 348 339 339 SER SER A . n 
A 1 349 GLY 349 340 340 GLY GLY A . n 
A 1 350 VAL 350 341 341 VAL VAL A . n 
A 1 351 GLY 351 342 342 GLY GLY A . n 
A 1 352 ARG 352 343 343 ARG ARG A . n 
A 1 353 LEU 353 344 344 LEU LEU A . n 
A 1 354 LEU 354 345 345 LEU LEU A . n 
A 1 355 PHE 355 346 346 PHE PHE A . n 
A 1 356 GLY 356 347 347 GLY GLY A . n 
A 1 357 ARG 357 348 348 ARG ARG A . n 
A 1 358 ILE 358 349 349 ILE ILE A . n 
A 1 359 ALA 359 350 350 ALA ALA A . n 
A 1 360 ASP 360 351 351 ASP ASP A . n 
A 1 361 TYR 361 352 352 TYR TYR A . n 
A 1 362 VAL 362 353 353 VAL VAL A . n 
A 1 363 PRO 363 354 354 PRO PRO A . n 
A 1 364 GLY 364 355 355 GLY GLY A . n 
A 1 365 VAL 365 356 356 VAL VAL A . n 
A 1 366 LYS 366 357 357 LYS LYS A . n 
A 1 367 LYS 367 358 358 LYS LYS A . n 
A 1 368 VAL 368 359 359 VAL VAL A . n 
A 1 369 TYR 369 360 360 TYR TYR A . n 
A 1 370 LEU 370 361 361 LEU LEU A . n 
A 1 371 GLN 371 362 362 GLN GLN A . n 
A 1 372 VAL 372 363 363 VAL VAL A . n 
A 1 373 LEU 373 364 364 LEU LEU A . n 
A 1 374 SER 374 365 365 SER SER A . n 
A 1 375 PHE 375 366 366 PHE PHE A . n 
A 1 376 PHE 376 367 367 PHE PHE A . n 
A 1 377 PHE 377 368 368 PHE PHE A . n 
A 1 378 ILE 378 369 369 ILE ILE A . n 
A 1 379 GLY 379 370 370 GLY GLY A . n 
A 1 380 LEU 380 371 371 LEU LEU A . n 
A 1 381 MET 381 372 372 MET MET A . n 
A 1 382 SER 382 373 373 SER SER A . n 
A 1 383 MET 383 374 374 MET MET A . n 
A 1 384 MET 384 375 375 MET MET A . n 
A 1 385 ILE 385 376 376 ILE ILE A . n 
A 1 386 PRO 386 377 377 PRO PRO A . n 
A 1 387 LEU 387 378 378 LEU LEU A . n 
A 1 388 CYS 388 379 379 CYS CYS A . n 
A 1 389 SER 389 380 380 SER SER A . n 
A 1 390 ILE 390 381 381 ILE ILE A . n 
A 1 391 PHE 391 382 382 PHE PHE A . n 
A 1 392 GLY 392 383 383 GLY GLY A . n 
A 1 393 ALA 393 384 384 ALA ALA A . n 
A 1 394 LEU 394 385 385 LEU LEU A . n 
A 1 395 ILE 395 386 386 ILE ILE A . n 
A 1 396 ALA 396 387 387 ALA ALA A . n 
A 1 397 VAL 397 388 388 VAL VAL A . n 
A 1 398 CYS 398 389 389 CYS CYS A . n 
A 1 399 LEU 399 390 390 LEU LEU A . n 
A 1 400 ILE 400 391 391 ILE ILE A . n 
A 1 401 MET 401 392 392 MET MET A . n 
A 1 402 GLY 402 393 393 GLY GLY A . n 
A 1 403 LEU 403 394 394 LEU LEU A . n 
A 1 404 PHE 404 395 395 PHE PHE A . n 
A 1 405 ASP 405 396 396 ASP ASP A . n 
A 1 406 GLY 406 397 397 GLY GLY A . n 
A 1 407 CYS 407 398 398 CYS CYS A . n 
A 1 408 PHE 408 399 399 PHE PHE A . n 
A 1 409 ILE 409 400 400 ILE ILE A . n 
A 1 410 SER 410 401 401 SER SER A . n 
A 1 411 ILE 411 402 402 ILE ILE A . n 
A 1 412 MET 412 403 403 MET MET A . n 
A 1 413 ALA 413 404 404 ALA ALA A . n 
A 1 414 PRO 414 405 405 PRO PRO A . n 
A 1 415 ILE 415 406 406 ILE ILE A . n 
A 1 416 ALA 416 407 407 ALA ALA A . n 
A 1 417 PHE 417 408 408 PHE PHE A . n 
A 1 418 GLU 418 409 409 GLU GLU A . n 
A 1 419 LEU 419 410 410 LEU LEU A . n 
A 1 420 VAL 420 411 411 VAL VAL A . n 
A 1 421 GLY 421 412 412 GLY GLY A . n 
A 1 422 ALA 422 413 413 ALA ALA A . n 
A 1 423 GLN 423 414 414 GLN GLN A . n 
A 1 424 ASP 424 415 415 ASP ASP A . n 
A 1 425 VAL 425 416 416 VAL VAL A . n 
A 1 426 SER 426 417 417 SER SER A . n 
A 1 427 GLN 427 418 418 GLN GLN A . n 
A 1 428 ALA 428 419 419 ALA ALA A . n 
A 1 429 ILE 429 420 420 ILE ILE A . n 
A 1 430 GLY 430 421 421 GLY GLY A . n 
A 1 431 PHE 431 422 422 PHE PHE A . n 
A 1 432 LEU 432 423 423 LEU LEU A . n 
A 1 433 LEU 433 424 424 LEU LEU A . n 
A 1 434 GLY 434 425 425 GLY GLY A . n 
A 1 435 PHE 435 426 426 PHE PHE A . n 
A 1 436 MET 436 427 427 MET MET A . n 
A 1 437 SER 437 428 428 SER SER A . n 
A 1 438 ILE 438 429 429 ILE ILE A . n 
A 1 439 PRO 439 430 430 PRO PRO A . n 
A 1 440 MET 440 431 431 MET MET A . n 
A 1 441 THR 441 432 432 THR THR A . n 
A 1 442 VAL 442 433 433 VAL VAL A . n 
A 1 443 GLY 443 434 434 GLY GLY A . n 
A 1 444 PRO 444 435 435 PRO PRO A . n 
A 1 445 PRO 445 436 436 PRO PRO A . n 
A 1 446 ILE 446 437 437 ILE ILE A . n 
A 1 447 ALA 447 438 438 ALA ALA A . n 
A 1 448 GLY 448 439 439 GLY GLY A . n 
A 1 449 LEU 449 440 440 LEU LEU A . n 
A 1 450 LEU 450 441 441 LEU LEU A . n 
A 1 451 ARG 451 442 442 ARG ARG A . n 
A 1 452 ASP 452 443 443 ASP ASP A . n 
A 1 453 LYS 453 444 444 LYS LYS A . n 
A 1 454 LEU 454 445 445 LEU LEU A . n 
A 1 455 GLY 455 446 446 GLY GLY A . n 
A 1 456 SER 456 447 447 SER SER A . n 
A 1 457 TYR 457 448 448 TYR TYR A . n 
A 1 458 ASP 458 449 449 ASP ASP A . n 
A 1 459 VAL 459 450 450 VAL VAL A . n 
A 1 460 ALA 460 451 451 ALA ALA A . n 
A 1 461 PHE 461 452 452 PHE PHE A . n 
A 1 462 TYR 462 453 453 TYR TYR A . n 
A 1 463 LEU 463 454 454 LEU LEU A . n 
A 1 464 ALA 464 455 455 ALA ALA A . n 
A 1 465 GLY 465 456 456 GLY GLY A . n 
A 1 466 VAL 466 457 457 VAL VAL A . n 
A 1 467 PRO 467 458 458 PRO PRO A . n 
A 1 468 PRO 468 459 459 PRO PRO A . n 
A 1 469 LEU 469 460 460 LEU LEU A . n 
A 1 470 ILE 470 461 461 ILE ILE A . n 
A 1 471 GLY 471 462 462 GLY GLY A . n 
A 1 472 GLY 472 463 463 GLY GLY A . n 
A 1 473 ALA 473 464 464 ALA ALA A . n 
A 1 474 VAL 474 465 465 VAL VAL A . n 
A 1 475 LEU 475 466 466 LEU LEU A . n 
A 1 476 CYS 476 467 467 CYS CYS A . n 
A 1 477 PHE 477 468 468 PHE PHE A . n 
A 1 478 ILE 478 469 469 ILE ILE A . n 
A 1 479 PRO 479 470 470 PRO PRO A . n 
A 1 480 SER 480 471 471 SER SER A . n 
A 1 481 ARG 481 472 472 ARG ARG A . n 
A 1 482 LEU 482 473 473 LEU LEU A . n 
A 1 483 GLU 483 474 474 GLU GLU A . n 
A 1 484 GLU 484 475 475 GLU GLU A . n 
A 1 485 GLU 485 476 476 GLU GLU A . n 
A 1 486 LEU 486 477 477 LEU LEU A . n 
A 1 487 ARG 487 478 478 ARG ARG A . n 
A 1 488 ARG 488 479 479 ARG ARG A . n 
A 1 489 ARG 489 480 480 ARG ARG A . n 
A 1 490 LEU 490 481 481 LEU LEU A . n 
A 1 491 THR 491 482 482 THR THR A . n 
A 1 492 GLU 492 483 483 GLU GLU A . n 
A 1 493 PRO 493 484 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        T44 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   T44 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         B 
_pdbx_nonpoly_scheme.entity_id       2 
_pdbx_nonpoly_scheme.mon_id          T44 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     600 
_pdbx_nonpoly_scheme.auth_seq_num    600 
_pdbx_nonpoly_scheme.pdb_mon_id      T44 
_pdbx_nonpoly_scheme.auth_mon_id     T44 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GSZ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GSZ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GSZ 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9GSZ 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 3044 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.521  ? 4128 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 10.779 ? 1050 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.040  ? 478  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 501  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9GSZ 
_struct.title                        'Human monocarboxylate transporter 10 bound to L-thyroxine' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GSZ 
_struct_keywords.text            'L-thyroxine, Thyroid, Transporter, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    MOT10_HUMAN 
_struct_ref.pdbx_db_accession          Q8TF71 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPPEGGWGWLVMLAAMWC
NGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSS
FVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIF
MFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNE
RFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFI
SIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIP
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9GSZ 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 10 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 479 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q8TF71 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  470 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       470 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9GSZ MET A 1   ? UNP Q8TF71 ? ? 'initiating methionine' -8  1  
1 9GSZ ASP A 2   ? UNP Q8TF71 ? ? 'expression tag'        -7  2  
1 9GSZ TYR A 3   ? UNP Q8TF71 ? ? 'expression tag'        -6  3  
1 9GSZ LYS A 4   ? UNP Q8TF71 ? ? 'expression tag'        -5  4  
1 9GSZ ASP A 5   ? UNP Q8TF71 ? ? 'expression tag'        -4  5  
1 9GSZ ASP A 6   ? UNP Q8TF71 ? ? 'expression tag'        -3  6  
1 9GSZ ASP A 7   ? UNP Q8TF71 ? ? 'expression tag'        -2  7  
1 9GSZ ASP A 8   ? UNP Q8TF71 ? ? 'expression tag'        -1  8  
1 9GSZ LYS A 9   ? UNP Q8TF71 ? ? 'expression tag'        0   9  
1 9GSZ SER A 480 ? UNP Q8TF71 ? ? 'expression tag'        471 10 
1 9GSZ ARG A 481 ? UNP Q8TF71 ? ? 'expression tag'        472 11 
1 9GSZ LEU A 482 ? UNP Q8TF71 ? ? 'expression tag'        473 12 
1 9GSZ GLU A 483 ? UNP Q8TF71 ? ? 'expression tag'        474 13 
1 9GSZ GLU A 484 ? UNP Q8TF71 ? ? 'expression tag'        475 14 
1 9GSZ GLU A 485 ? UNP Q8TF71 ? ? 'expression tag'        476 15 
1 9GSZ LEU A 486 ? UNP Q8TF71 ? ? 'expression tag'        477 16 
1 9GSZ ARG A 487 ? UNP Q8TF71 ? ? 'expression tag'        478 17 
1 9GSZ ARG A 488 ? UNP Q8TF71 ? ? 'expression tag'        479 18 
1 9GSZ ARG A 489 ? UNP Q8TF71 ? ? 'expression tag'        480 19 
1 9GSZ LEU A 490 ? UNP Q8TF71 ? ? 'expression tag'        481 20 
1 9GSZ THR A 491 ? UNP Q8TF71 ? ? 'expression tag'        482 21 
1 9GSZ GLU A 492 ? UNP Q8TF71 ? ? 'expression tag'        483 22 
1 9GSZ PRO A 493 ? UNP Q8TF71 ? ? 'expression tag'        484 23 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 TRP A 80  ? THR A 110 ? TRP A 71  THR A 101 1 ? 31 
HELX_P HELX_P2  AA2 LYS A 118 ? GLY A 149 ? LYS A 109 GLY A 140 1 ? 32 
HELX_P HELX_P3  AA3 THR A 153 ? SER A 169 ? THR A 144 SER A 160 1 ? 17 
HELX_P HELX_P4  AA4 PRO A 176 ? TYR A 181 ? PRO A 167 TYR A 172 1 ? 6  
HELX_P HELX_P5  AA5 GLY A 182 ? GLY A 201 ? GLY A 173 GLY A 192 1 ? 20 
HELX_P HELX_P6  AA6 GLY A 209 ? VAL A 237 ? GLY A 200 VAL A 228 1 ? 29 
HELX_P HELX_P7  AA7 GLY A 238 ? LEU A 246 ? GLY A 229 LEU A 237 1 ? 9  
HELX_P HELX_P8  AA8 LEU A 246 ? GLY A 257 ? LEU A 237 GLY A 248 1 ? 12 
HELX_P HELX_P9  AA9 PHE A 294 ? LYS A 298 ? PHE A 285 LYS A 289 5 ? 5  
HELX_P HELX_P10 AB1 VAL A 299 ? LEU A 313 ? VAL A 290 LEU A 304 1 ? 15 
HELX_P HELX_P11 AB2 PHE A 317 ? VAL A 327 ? PHE A 308 VAL A 318 1 ? 11 
HELX_P HELX_P12 AB3 LYS A 337 ? ASP A 360 ? LYS A 328 ASP A 351 1 ? 24 
HELX_P HELX_P13 AB4 TYR A 361 ? LYS A 366 ? TYR A 352 LYS A 357 1 ? 6  
HELX_P HELX_P14 AB5 TYR A 369 ? ILE A 385 ? TYR A 360 ILE A 376 1 ? 17 
HELX_P HELX_P15 AB6 ILE A 390 ? VAL A 420 ? ILE A 381 VAL A 411 1 ? 31 
HELX_P HELX_P16 AB7 GLY A 421 ? GLN A 423 ? GLY A 412 GLN A 414 5 ? 3  
HELX_P HELX_P17 AB8 ASP A 424 ? LEU A 450 ? ASP A 415 LEU A 441 1 ? 27 
HELX_P HELX_P18 AB9 TYR A 457 ? ALA A 464 ? TYR A 448 ALA A 455 1 ? 8  
HELX_P HELX_P19 AC1 GLY A 465 ? PHE A 477 ? GLY A 456 PHE A 468 1 ? 13 
HELX_P HELX_P20 AC2 GLU A 483 ? ARG A 489 ? GLU A 474 ARG A 480 5 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_pdbx_entry_details.entry_id                   9GSZ 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 CYS A 91  ? ? -37.51  -36.52 
2 1 PHE A 102 ? ? 39.65   51.47  
3 1 THR A 144 ? ? 74.22   -21.43 
4 1 PHE A 195 ? ? -141.57 28.57  
5 1 LEU A 237 ? ? -59.57  -6.62  
6 1 ASN A 319 ? ? 82.39   -0.75  
7 1 PHE A 468 ? ? -96.02  34.92  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9GSZ 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'AB INITIO MODEL' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       'model generated from PDB 7YR5' 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   ITasser 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    9GSZ 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.8 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               57707 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Monocarboxylate transporter 10 bound to anti-alfa nanobody and L-thyroxine' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9GSZ 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   200 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9GSZ 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   279.15 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9GSZ 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -8  ? A MET 1   
2   1 Y 1 A ASP -7  ? A ASP 2   
3   1 Y 1 A TYR -6  ? A TYR 3   
4   1 Y 1 A LYS -5  ? A LYS 4   
5   1 Y 1 A ASP -4  ? A ASP 5   
6   1 Y 1 A ASP -3  ? A ASP 6   
7   1 Y 1 A ASP -2  ? A ASP 7   
8   1 Y 1 A ASP -1  ? A ASP 8   
9   1 Y 1 A LYS 0   ? A LYS 9   
10  1 Y 1 A MET 1   ? A MET 10  
11  1 Y 1 A VAL 2   ? A VAL 11  
12  1 Y 1 A LEU 3   ? A LEU 12  
13  1 Y 1 A SER 4   ? A SER 13  
14  1 Y 1 A GLN 5   ? A GLN 14  
15  1 Y 1 A GLU 6   ? A GLU 15  
16  1 Y 1 A GLU 7   ? A GLU 16  
17  1 Y 1 A PRO 8   ? A PRO 17  
18  1 Y 1 A ASP 9   ? A ASP 18  
19  1 Y 1 A SER 10  ? A SER 19  
20  1 Y 1 A ALA 11  ? A ALA 20  
21  1 Y 1 A ARG 12  ? A ARG 21  
22  1 Y 1 A GLY 13  ? A GLY 22  
23  1 Y 1 A THR 14  ? A THR 23  
24  1 Y 1 A SER 15  ? A SER 24  
25  1 Y 1 A GLU 16  ? A GLU 25  
26  1 Y 1 A ALA 17  ? A ALA 26  
27  1 Y 1 A GLN 18  ? A GLN 27  
28  1 Y 1 A PRO 19  ? A PRO 28  
29  1 Y 1 A LEU 20  ? A LEU 29  
30  1 Y 1 A GLY 21  ? A GLY 30  
31  1 Y 1 A PRO 22  ? A PRO 31  
32  1 Y 1 A ALA 23  ? A ALA 32  
33  1 Y 1 A PRO 24  ? A PRO 33  
34  1 Y 1 A THR 25  ? A THR 34  
35  1 Y 1 A GLY 26  ? A GLY 35  
36  1 Y 1 A ALA 27  ? A ALA 36  
37  1 Y 1 A ALA 28  ? A ALA 37  
38  1 Y 1 A PRO 29  ? A PRO 38  
39  1 Y 1 A PRO 30  ? A PRO 39  
40  1 Y 1 A PRO 31  ? A PRO 40  
41  1 Y 1 A GLY 32  ? A GLY 41  
42  1 Y 1 A PRO 33  ? A PRO 42  
43  1 Y 1 A GLY 34  ? A GLY 43  
44  1 Y 1 A PRO 35  ? A PRO 44  
45  1 Y 1 A SER 36  ? A SER 45  
46  1 Y 1 A ASP 37  ? A ASP 46  
47  1 Y 1 A SER 38  ? A SER 47  
48  1 Y 1 A PRO 39  ? A PRO 48  
49  1 Y 1 A GLU 40  ? A GLU 49  
50  1 Y 1 A ALA 41  ? A ALA 50  
51  1 Y 1 A ALA 42  ? A ALA 51  
52  1 Y 1 A VAL 43  ? A VAL 52  
53  1 Y 1 A GLU 44  ? A GLU 53  
54  1 Y 1 A LYS 45  ? A LYS 54  
55  1 Y 1 A VAL 46  ? A VAL 55  
56  1 Y 1 A GLU 47  ? A GLU 56  
57  1 Y 1 A VAL 48  ? A VAL 57  
58  1 Y 1 A GLU 49  ? A GLU 58  
59  1 Y 1 A LEU 50  ? A LEU 59  
60  1 Y 1 A ALA 51  ? A ALA 60  
61  1 Y 1 A GLY 52  ? A GLY 61  
62  1 Y 1 A PRO 53  ? A PRO 62  
63  1 Y 1 A ALA 54  ? A ALA 63  
64  1 Y 1 A THR 55  ? A THR 64  
65  1 Y 1 A ALA 56  ? A ALA 65  
66  1 Y 1 A GLU 57  ? A GLU 66  
67  1 Y 1 A PRO 58  ? A PRO 67  
68  1 Y 1 A HIS 59  ? A HIS 68  
69  1 Y 1 A GLU 60  ? A GLU 69  
70  1 Y 1 A PRO 61  ? A PRO 70  
71  1 Y 1 A PRO 62  ? A PRO 71  
72  1 Y 1 A GLU 63  ? A GLU 72  
73  1 Y 1 A PRO 64  ? A PRO 73  
74  1 Y 1 A PRO 65  ? A PRO 74  
75  1 Y 1 A GLU 66  ? A GLU 75  
76  1 Y 1 A GLY 67  ? A GLY 76  
77  1 Y 1 A GLY 68  ? A GLY 77  
78  1 Y 1 A LYS 105 ? A LYS 114 
79  1 Y 1 A ASP 106 ? A ASP 115 
80  1 Y 1 A ASP 107 ? A ASP 116 
81  1 Y 1 A ALA 255 ? A ALA 264 
82  1 Y 1 A THR 256 ? A THR 265 
83  1 Y 1 A SER 257 ? A SER 266 
84  1 Y 1 A THR 258 ? A THR 267 
85  1 Y 1 A LYS 259 ? A LYS 268 
86  1 Y 1 A ASP 260 ? A ASP 269 
87  1 Y 1 A LYS 261 ? A LYS 270 
88  1 Y 1 A GLU 262 ? A GLU 271 
89  1 Y 1 A SER 263 ? A SER 272 
90  1 Y 1 A GLY 264 ? A GLY 273 
91  1 Y 1 A GLY 265 ? A GLY 274 
92  1 Y 1 A SER 266 ? A SER 275 
93  1 Y 1 A GLY 267 ? A GLY 276 
94  1 Y 1 A SER 268 ? A SER 277 
95  1 Y 1 A SER 269 ? A SER 278 
96  1 Y 1 A LEU 270 ? A LEU 279 
97  1 Y 1 A PHE 271 ? A PHE 280 
98  1 Y 1 A SER 272 ? A SER 281 
99  1 Y 1 A ARG 273 ? A ARG 282 
100 1 Y 1 A LYS 274 ? A LYS 283 
101 1 Y 1 A LYS 275 ? A LYS 284 
102 1 Y 1 A PHE 276 ? A PHE 285 
103 1 Y 1 A SER 277 ? A SER 286 
104 1 Y 1 A PRO 278 ? A PRO 287 
105 1 Y 1 A PRO 279 ? A PRO 288 
106 1 Y 1 A LYS 280 ? A LYS 289 
107 1 Y 1 A LYS 281 ? A LYS 290 
108 1 Y 1 A ILE 282 ? A ILE 291 
109 1 Y 1 A PHE 283 ? A PHE 292 
110 1 Y 1 A PRO 484 ? A PRO 493 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
CYS N      N N N 74  
CYS CA     C N R 75  
CYS C      C N N 76  
CYS O      O N N 77  
CYS CB     C N N 78  
CYS SG     S N N 79  
CYS OXT    O N N 80  
CYS H      H N N 81  
CYS H2     H N N 82  
CYS HA     H N N 83  
CYS HB2    H N N 84  
CYS HB3    H N N 85  
CYS HG     H N N 86  
CYS HXT    H N N 87  
GLN N      N N N 88  
GLN CA     C N S 89  
GLN C      C N N 90  
GLN O      O N N 91  
GLN CB     C N N 92  
GLN CG     C N N 93  
GLN CD     C N N 94  
GLN OE1    O N N 95  
GLN NE2    N N N 96  
GLN OXT    O N N 97  
GLN H      H N N 98  
GLN H2     H N N 99  
GLN HA     H N N 100 
GLN HB2    H N N 101 
GLN HB3    H N N 102 
GLN HG2    H N N 103 
GLN HG3    H N N 104 
GLN HE21   H N N 105 
GLN HE22   H N N 106 
GLN HXT    H N N 107 
GLU N      N N N 108 
GLU CA     C N S 109 
GLU C      C N N 110 
GLU O      O N N 111 
GLU CB     C N N 112 
GLU CG     C N N 113 
GLU CD     C N N 114 
GLU OE1    O N N 115 
GLU OE2    O N N 116 
GLU OXT    O N N 117 
GLU H      H N N 118 
GLU H2     H N N 119 
GLU HA     H N N 120 
GLU HB2    H N N 121 
GLU HB3    H N N 122 
GLU HG2    H N N 123 
GLU HG3    H N N 124 
GLU HE2    H N N 125 
GLU HXT    H N N 126 
GLY N      N N N 127 
GLY CA     C N N 128 
GLY C      C N N 129 
GLY O      O N N 130 
GLY OXT    O N N 131 
GLY H      H N N 132 
GLY H2     H N N 133 
GLY HA2    H N N 134 
GLY HA3    H N N 135 
GLY HXT    H N N 136 
HIS N      N N N 137 
HIS CA     C N S 138 
HIS C      C N N 139 
HIS O      O N N 140 
HIS CB     C N N 141 
HIS CG     C Y N 142 
HIS ND1    N Y N 143 
HIS CD2    C Y N 144 
HIS CE1    C Y N 145 
HIS NE2    N Y N 146 
HIS OXT    O N N 147 
HIS H      H N N 148 
HIS H2     H N N 149 
HIS HA     H N N 150 
HIS HB2    H N N 151 
HIS HB3    H N N 152 
HIS HD1    H N N 153 
HIS HD2    H N N 154 
HIS HE1    H N N 155 
HIS HE2    H N N 156 
HIS HXT    H N N 157 
ILE N      N N N 158 
ILE CA     C N S 159 
ILE C      C N N 160 
ILE O      O N N 161 
ILE CB     C N S 162 
ILE CG1    C N N 163 
ILE CG2    C N N 164 
ILE CD1    C N N 165 
ILE OXT    O N N 166 
ILE H      H N N 167 
ILE H2     H N N 168 
ILE HA     H N N 169 
ILE HB     H N N 170 
ILE HG12   H N N 171 
ILE HG13   H N N 172 
ILE HG21   H N N 173 
ILE HG22   H N N 174 
ILE HG23   H N N 175 
ILE HD11   H N N 176 
ILE HD12   H N N 177 
ILE HD13   H N N 178 
ILE HXT    H N N 179 
LEU N      N N N 180 
LEU CA     C N S 181 
LEU C      C N N 182 
LEU O      O N N 183 
LEU CB     C N N 184 
LEU CG     C N N 185 
LEU CD1    C N N 186 
LEU CD2    C N N 187 
LEU OXT    O N N 188 
LEU H      H N N 189 
LEU H2     H N N 190 
LEU HA     H N N 191 
LEU HB2    H N N 192 
LEU HB3    H N N 193 
LEU HG     H N N 194 
LEU HD11   H N N 195 
LEU HD12   H N N 196 
LEU HD13   H N N 197 
LEU HD21   H N N 198 
LEU HD22   H N N 199 
LEU HD23   H N N 200 
LEU HXT    H N N 201 
LYS N      N N N 202 
LYS CA     C N S 203 
LYS C      C N N 204 
LYS O      O N N 205 
LYS CB     C N N 206 
LYS CG     C N N 207 
LYS CD     C N N 208 
LYS CE     C N N 209 
LYS NZ     N N N 210 
LYS OXT    O N N 211 
LYS H      H N N 212 
LYS H2     H N N 213 
LYS HA     H N N 214 
LYS HB2    H N N 215 
LYS HB3    H N N 216 
LYS HG2    H N N 217 
LYS HG3    H N N 218 
LYS HD2    H N N 219 
LYS HD3    H N N 220 
LYS HE2    H N N 221 
LYS HE3    H N N 222 
LYS HZ1    H N N 223 
LYS HZ2    H N N 224 
LYS HZ3    H N N 225 
LYS HXT    H N N 226 
MET N      N N N 227 
MET CA     C N S 228 
MET C      C N N 229 
MET O      O N N 230 
MET CB     C N N 231 
MET CG     C N N 232 
MET SD     S N N 233 
MET CE     C N N 234 
MET OXT    O N N 235 
MET H      H N N 236 
MET H2     H N N 237 
MET HA     H N N 238 
MET HB2    H N N 239 
MET HB3    H N N 240 
MET HG2    H N N 241 
MET HG3    H N N 242 
MET HE1    H N N 243 
MET HE2    H N N 244 
MET HE3    H N N 245 
MET HXT    H N N 246 
PHE N      N N N 247 
PHE CA     C N S 248 
PHE C      C N N 249 
PHE O      O N N 250 
PHE CB     C N N 251 
PHE CG     C Y N 252 
PHE CD1    C Y N 253 
PHE CD2    C Y N 254 
PHE CE1    C Y N 255 
PHE CE2    C Y N 256 
PHE CZ     C Y N 257 
PHE OXT    O N N 258 
PHE H      H N N 259 
PHE H2     H N N 260 
PHE HA     H N N 261 
PHE HB2    H N N 262 
PHE HB3    H N N 263 
PHE HD1    H N N 264 
PHE HD2    H N N 265 
PHE HE1    H N N 266 
PHE HE2    H N N 267 
PHE HZ     H N N 268 
PHE HXT    H N N 269 
PRO N      N N N 270 
PRO CA     C N S 271 
PRO C      C N N 272 
PRO O      O N N 273 
PRO CB     C N N 274 
PRO CG     C N N 275 
PRO CD     C N N 276 
PRO OXT    O N N 277 
PRO H      H N N 278 
PRO HA     H N N 279 
PRO HB2    H N N 280 
PRO HB3    H N N 281 
PRO HG2    H N N 282 
PRO HG3    H N N 283 
PRO HD2    H N N 284 
PRO HD3    H N N 285 
PRO HXT    H N N 286 
SER N      N N N 287 
SER CA     C N S 288 
SER C      C N N 289 
SER O      O N N 290 
SER CB     C N N 291 
SER OG     O N N 292 
SER OXT    O N N 293 
SER H      H N N 294 
SER H2     H N N 295 
SER HA     H N N 296 
SER HB2    H N N 297 
SER HB3    H N N 298 
SER HG     H N N 299 
SER HXT    H N N 300 
T44 C1     C Y N 301 
T44 C2     C Y N 302 
T44 C3     C Y N 303 
T44 C4     C Y N 304 
T44 C5     C Y N 305 
T44 C6     C Y N 306 
T44 C7     C N N 307 
T44 CA     C N S 308 
T44 C      C N N 309 
T44 "C1'"  C Y N 310 
T44 "C2'"  C Y N 311 
T44 "C3'"  C Y N 312 
T44 "C4'"  C Y N 313 
T44 "C5'"  C Y N 314 
T44 "C6'"  C Y N 315 
T44 N      N N N 316 
T44 O4     O N N 317 
T44 "O4'"  O N N 318 
T44 O      O N N 319 
T44 OXT    O N N 320 
T44 I3     I N N 321 
T44 "I3'"  I N N 322 
T44 I5     I N N 323 
T44 "I5'"  I N N 324 
T44 H1     H N N 325 
T44 H6     H N N 326 
T44 H71    H N N 327 
T44 H72    H N N 328 
T44 HA     H N N 329 
T44 "H2'"  H N N 330 
T44 "H6'"  H N N 331 
T44 H      H N N 332 
T44 H2     H N N 333 
T44 "HO4'" H N N 334 
T44 HXT    H N N 335 
THR N      N N N 336 
THR CA     C N S 337 
THR C      C N N 338 
THR O      O N N 339 
THR CB     C N R 340 
THR OG1    O N N 341 
THR CG2    C N N 342 
THR OXT    O N N 343 
THR H      H N N 344 
THR H2     H N N 345 
THR HA     H N N 346 
THR HB     H N N 347 
THR HG1    H N N 348 
THR HG21   H N N 349 
THR HG22   H N N 350 
THR HG23   H N N 351 
THR HXT    H N N 352 
TRP N      N N N 353 
TRP CA     C N S 354 
TRP C      C N N 355 
TRP O      O N N 356 
TRP CB     C N N 357 
TRP CG     C Y N 358 
TRP CD1    C Y N 359 
TRP CD2    C Y N 360 
TRP NE1    N Y N 361 
TRP CE2    C Y N 362 
TRP CE3    C Y N 363 
TRP CZ2    C Y N 364 
TRP CZ3    C Y N 365 
TRP CH2    C Y N 366 
TRP OXT    O N N 367 
TRP H      H N N 368 
TRP H2     H N N 369 
TRP HA     H N N 370 
TRP HB2    H N N 371 
TRP HB3    H N N 372 
TRP HD1    H N N 373 
TRP HE1    H N N 374 
TRP HE3    H N N 375 
TRP HZ2    H N N 376 
TRP HZ3    H N N 377 
TRP HH2    H N N 378 
TRP HXT    H N N 379 
TYR N      N N N 380 
TYR CA     C N S 381 
TYR C      C N N 382 
TYR O      O N N 383 
TYR CB     C N N 384 
TYR CG     C Y N 385 
TYR CD1    C Y N 386 
TYR CD2    C Y N 387 
TYR CE1    C Y N 388 
TYR CE2    C Y N 389 
TYR CZ     C Y N 390 
TYR OH     O N N 391 
TYR OXT    O N N 392 
TYR H      H N N 393 
TYR H2     H N N 394 
TYR HA     H N N 395 
TYR HB2    H N N 396 
TYR HB3    H N N 397 
TYR HD1    H N N 398 
TYR HD2    H N N 399 
TYR HE1    H N N 400 
TYR HE2    H N N 401 
TYR HH     H N N 402 
TYR HXT    H N N 403 
VAL N      N N N 404 
VAL CA     C N S 405 
VAL C      C N N 406 
VAL O      O N N 407 
VAL CB     C N N 408 
VAL CG1    C N N 409 
VAL CG2    C N N 410 
VAL OXT    O N N 411 
VAL H      H N N 412 
VAL H2     H N N 413 
VAL HA     H N N 414 
VAL HB     H N N 415 
VAL HG11   H N N 416 
VAL HG12   H N N 417 
VAL HG13   H N N 418 
VAL HG21   H N N 419 
VAL HG22   H N N 420 
VAL HG23   H N N 421 
VAL HXT    H N N 422 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
GLN N     CA     sing N N 83  
GLN N     H      sing N N 84  
GLN N     H2     sing N N 85  
GLN CA    C      sing N N 86  
GLN CA    CB     sing N N 87  
GLN CA    HA     sing N N 88  
GLN C     O      doub N N 89  
GLN C     OXT    sing N N 90  
GLN CB    CG     sing N N 91  
GLN CB    HB2    sing N N 92  
GLN CB    HB3    sing N N 93  
GLN CG    CD     sing N N 94  
GLN CG    HG2    sing N N 95  
GLN CG    HG3    sing N N 96  
GLN CD    OE1    doub N N 97  
GLN CD    NE2    sing N N 98  
GLN NE2   HE21   sing N N 99  
GLN NE2   HE22   sing N N 100 
GLN OXT   HXT    sing N N 101 
GLU N     CA     sing N N 102 
GLU N     H      sing N N 103 
GLU N     H2     sing N N 104 
GLU CA    C      sing N N 105 
GLU CA    CB     sing N N 106 
GLU CA    HA     sing N N 107 
GLU C     O      doub N N 108 
GLU C     OXT    sing N N 109 
GLU CB    CG     sing N N 110 
GLU CB    HB2    sing N N 111 
GLU CB    HB3    sing N N 112 
GLU CG    CD     sing N N 113 
GLU CG    HG2    sing N N 114 
GLU CG    HG3    sing N N 115 
GLU CD    OE1    doub N N 116 
GLU CD    OE2    sing N N 117 
GLU OE2   HE2    sing N N 118 
GLU OXT   HXT    sing N N 119 
GLY N     CA     sing N N 120 
GLY N     H      sing N N 121 
GLY N     H2     sing N N 122 
GLY CA    C      sing N N 123 
GLY CA    HA2    sing N N 124 
GLY CA    HA3    sing N N 125 
GLY C     O      doub N N 126 
GLY C     OXT    sing N N 127 
GLY OXT   HXT    sing N N 128 
HIS N     CA     sing N N 129 
HIS N     H      sing N N 130 
HIS N     H2     sing N N 131 
HIS CA    C      sing N N 132 
HIS CA    CB     sing N N 133 
HIS CA    HA     sing N N 134 
HIS C     O      doub N N 135 
HIS C     OXT    sing N N 136 
HIS CB    CG     sing N N 137 
HIS CB    HB2    sing N N 138 
HIS CB    HB3    sing N N 139 
HIS CG    ND1    sing Y N 140 
HIS CG    CD2    doub Y N 141 
HIS ND1   CE1    doub Y N 142 
HIS ND1   HD1    sing N N 143 
HIS CD2   NE2    sing Y N 144 
HIS CD2   HD2    sing N N 145 
HIS CE1   NE2    sing Y N 146 
HIS CE1   HE1    sing N N 147 
HIS NE2   HE2    sing N N 148 
HIS OXT   HXT    sing N N 149 
ILE N     CA     sing N N 150 
ILE N     H      sing N N 151 
ILE N     H2     sing N N 152 
ILE CA    C      sing N N 153 
ILE CA    CB     sing N N 154 
ILE CA    HA     sing N N 155 
ILE C     O      doub N N 156 
ILE C     OXT    sing N N 157 
ILE CB    CG1    sing N N 158 
ILE CB    CG2    sing N N 159 
ILE CB    HB     sing N N 160 
ILE CG1   CD1    sing N N 161 
ILE CG1   HG12   sing N N 162 
ILE CG1   HG13   sing N N 163 
ILE CG2   HG21   sing N N 164 
ILE CG2   HG22   sing N N 165 
ILE CG2   HG23   sing N N 166 
ILE CD1   HD11   sing N N 167 
ILE CD1   HD12   sing N N 168 
ILE CD1   HD13   sing N N 169 
ILE OXT   HXT    sing N N 170 
LEU N     CA     sing N N 171 
LEU N     H      sing N N 172 
LEU N     H2     sing N N 173 
LEU CA    C      sing N N 174 
LEU CA    CB     sing N N 175 
LEU CA    HA     sing N N 176 
LEU C     O      doub N N 177 
LEU C     OXT    sing N N 178 
LEU CB    CG     sing N N 179 
LEU CB    HB2    sing N N 180 
LEU CB    HB3    sing N N 181 
LEU CG    CD1    sing N N 182 
LEU CG    CD2    sing N N 183 
LEU CG    HG     sing N N 184 
LEU CD1   HD11   sing N N 185 
LEU CD1   HD12   sing N N 186 
LEU CD1   HD13   sing N N 187 
LEU CD2   HD21   sing N N 188 
LEU CD2   HD22   sing N N 189 
LEU CD2   HD23   sing N N 190 
LEU OXT   HXT    sing N N 191 
LYS N     CA     sing N N 192 
LYS N     H      sing N N 193 
LYS N     H2     sing N N 194 
LYS CA    C      sing N N 195 
LYS CA    CB     sing N N 196 
LYS CA    HA     sing N N 197 
LYS C     O      doub N N 198 
LYS C     OXT    sing N N 199 
LYS CB    CG     sing N N 200 
LYS CB    HB2    sing N N 201 
LYS CB    HB3    sing N N 202 
LYS CG    CD     sing N N 203 
LYS CG    HG2    sing N N 204 
LYS CG    HG3    sing N N 205 
LYS CD    CE     sing N N 206 
LYS CD    HD2    sing N N 207 
LYS CD    HD3    sing N N 208 
LYS CE    NZ     sing N N 209 
LYS CE    HE2    sing N N 210 
LYS CE    HE3    sing N N 211 
LYS NZ    HZ1    sing N N 212 
LYS NZ    HZ2    sing N N 213 
LYS NZ    HZ3    sing N N 214 
LYS OXT   HXT    sing N N 215 
MET N     CA     sing N N 216 
MET N     H      sing N N 217 
MET N     H2     sing N N 218 
MET CA    C      sing N N 219 
MET CA    CB     sing N N 220 
MET CA    HA     sing N N 221 
MET C     O      doub N N 222 
MET C     OXT    sing N N 223 
MET CB    CG     sing N N 224 
MET CB    HB2    sing N N 225 
MET CB    HB3    sing N N 226 
MET CG    SD     sing N N 227 
MET CG    HG2    sing N N 228 
MET CG    HG3    sing N N 229 
MET SD    CE     sing N N 230 
MET CE    HE1    sing N N 231 
MET CE    HE2    sing N N 232 
MET CE    HE3    sing N N 233 
MET OXT   HXT    sing N N 234 
PHE N     CA     sing N N 235 
PHE N     H      sing N N 236 
PHE N     H2     sing N N 237 
PHE CA    C      sing N N 238 
PHE CA    CB     sing N N 239 
PHE CA    HA     sing N N 240 
PHE C     O      doub N N 241 
PHE C     OXT    sing N N 242 
PHE CB    CG     sing N N 243 
PHE CB    HB2    sing N N 244 
PHE CB    HB3    sing N N 245 
PHE CG    CD1    doub Y N 246 
PHE CG    CD2    sing Y N 247 
PHE CD1   CE1    sing Y N 248 
PHE CD1   HD1    sing N N 249 
PHE CD2   CE2    doub Y N 250 
PHE CD2   HD2    sing N N 251 
PHE CE1   CZ     doub Y N 252 
PHE CE1   HE1    sing N N 253 
PHE CE2   CZ     sing Y N 254 
PHE CE2   HE2    sing N N 255 
PHE CZ    HZ     sing N N 256 
PHE OXT   HXT    sing N N 257 
PRO N     CA     sing N N 258 
PRO N     CD     sing N N 259 
PRO N     H      sing N N 260 
PRO CA    C      sing N N 261 
PRO CA    CB     sing N N 262 
PRO CA    HA     sing N N 263 
PRO C     O      doub N N 264 
PRO C     OXT    sing N N 265 
PRO CB    CG     sing N N 266 
PRO CB    HB2    sing N N 267 
PRO CB    HB3    sing N N 268 
PRO CG    CD     sing N N 269 
PRO CG    HG2    sing N N 270 
PRO CG    HG3    sing N N 271 
PRO CD    HD2    sing N N 272 
PRO CD    HD3    sing N N 273 
PRO OXT   HXT    sing N N 274 
SER N     CA     sing N N 275 
SER N     H      sing N N 276 
SER N     H2     sing N N 277 
SER CA    C      sing N N 278 
SER CA    CB     sing N N 279 
SER CA    HA     sing N N 280 
SER C     O      doub N N 281 
SER C     OXT    sing N N 282 
SER CB    OG     sing N N 283 
SER CB    HB2    sing N N 284 
SER CB    HB3    sing N N 285 
SER OG    HG     sing N N 286 
SER OXT   HXT    sing N N 287 
T44 C1    C2     doub Y N 288 
T44 C1    C6     sing Y N 289 
T44 C1    C7     sing N N 290 
T44 C2    C3     sing Y N 291 
T44 C2    H1     sing N N 292 
T44 C3    C4     doub Y N 293 
T44 C3    I3     sing N N 294 
T44 C4    C5     sing Y N 295 
T44 C4    O4     sing N N 296 
T44 C5    C6     doub Y N 297 
T44 C5    I5     sing N N 298 
T44 C6    H6     sing N N 299 
T44 C7    CA     sing N N 300 
T44 C7    H71    sing N N 301 
T44 C7    H72    sing N N 302 
T44 CA    C      sing N N 303 
T44 CA    N      sing N N 304 
T44 CA    HA     sing N N 305 
T44 C     O      doub N N 306 
T44 C     OXT    sing N N 307 
T44 "C1'" "C2'"  doub Y N 308 
T44 "C1'" "C6'"  sing Y N 309 
T44 "C1'" O4     sing N N 310 
T44 "C2'" "C3'"  sing Y N 311 
T44 "C2'" "H2'"  sing N N 312 
T44 "C3'" "C4'"  doub Y N 313 
T44 "C3'" "I3'"  sing N N 314 
T44 "C4'" "C5'"  sing Y N 315 
T44 "C4'" "O4'"  sing N N 316 
T44 "C5'" "C6'"  doub Y N 317 
T44 "C5'" "I5'"  sing N N 318 
T44 "C6'" "H6'"  sing N N 319 
T44 N     H      sing N N 320 
T44 N     H2     sing N N 321 
T44 "O4'" "HO4'" sing N N 322 
T44 OXT   HXT    sing N N 323 
THR N     CA     sing N N 324 
THR N     H      sing N N 325 
THR N     H2     sing N N 326 
THR CA    C      sing N N 327 
THR CA    CB     sing N N 328 
THR CA    HA     sing N N 329 
THR C     O      doub N N 330 
THR C     OXT    sing N N 331 
THR CB    OG1    sing N N 332 
THR CB    CG2    sing N N 333 
THR CB    HB     sing N N 334 
THR OG1   HG1    sing N N 335 
THR CG2   HG21   sing N N 336 
THR CG2   HG22   sing N N 337 
THR CG2   HG23   sing N N 338 
THR OXT   HXT    sing N N 339 
TRP N     CA     sing N N 340 
TRP N     H      sing N N 341 
TRP N     H2     sing N N 342 
TRP CA    C      sing N N 343 
TRP CA    CB     sing N N 344 
TRP CA    HA     sing N N 345 
TRP C     O      doub N N 346 
TRP C     OXT    sing N N 347 
TRP CB    CG     sing N N 348 
TRP CB    HB2    sing N N 349 
TRP CB    HB3    sing N N 350 
TRP CG    CD1    doub Y N 351 
TRP CG    CD2    sing Y N 352 
TRP CD1   NE1    sing Y N 353 
TRP CD1   HD1    sing N N 354 
TRP CD2   CE2    doub Y N 355 
TRP CD2   CE3    sing Y N 356 
TRP NE1   CE2    sing Y N 357 
TRP NE1   HE1    sing N N 358 
TRP CE2   CZ2    sing Y N 359 
TRP CE3   CZ3    doub Y N 360 
TRP CE3   HE3    sing N N 361 
TRP CZ2   CH2    doub Y N 362 
TRP CZ2   HZ2    sing N N 363 
TRP CZ3   CH2    sing Y N 364 
TRP CZ3   HZ3    sing N N 365 
TRP CH2   HH2    sing N N 366 
TRP OXT   HXT    sing N N 367 
TYR N     CA     sing N N 368 
TYR N     H      sing N N 369 
TYR N     H2     sing N N 370 
TYR CA    C      sing N N 371 
TYR CA    CB     sing N N 372 
TYR CA    HA     sing N N 373 
TYR C     O      doub N N 374 
TYR C     OXT    sing N N 375 
TYR CB    CG     sing N N 376 
TYR CB    HB2    sing N N 377 
TYR CB    HB3    sing N N 378 
TYR CG    CD1    doub Y N 379 
TYR CG    CD2    sing Y N 380 
TYR CD1   CE1    sing Y N 381 
TYR CD1   HD1    sing N N 382 
TYR CD2   CE2    doub Y N 383 
TYR CD2   HD2    sing N N 384 
TYR CE1   CZ     doub Y N 385 
TYR CE1   HE1    sing N N 386 
TYR CE2   CZ     sing Y N 387 
TYR CE2   HE2    sing N N 388 
TYR CZ    OH     sing N N 389 
TYR OH    HH     sing N N 390 
TYR OXT   HXT    sing N N 391 
VAL N     CA     sing N N 392 
VAL N     H      sing N N 393 
VAL N     H2     sing N N 394 
VAL CA    C      sing N N 395 
VAL CA    CB     sing N N 396 
VAL CA    HA     sing N N 397 
VAL C     O      doub N N 398 
VAL C     OXT    sing N N 399 
VAL CB    CG1    sing N N 400 
VAL CB    CG2    sing N N 401 
VAL CB    HB     sing N N 402 
VAL CG1   HG11   sing N N 403 
VAL CG1   HG12   sing N N 404 
VAL CG1   HG13   sing N N 405 
VAL CG2   HG21   sing N N 406 
VAL CG2   HG22   sing N N 407 
VAL CG2   HG23   sing N N 408 
VAL OXT   HXT    sing N N 409 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-09-16 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9GSZ 
_em_admin.last_update        2025-06-11 
_em_admin.map_release_date   2025-05-21 
_em_admin.title              'Human monocarboxylate transporter 10 bound to L-thyroxine' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 150 mM NaCl       1 'sodium chloride' 
1 25  mM C8H18N2O4S 2 Hepes             
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.05 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               6.5 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         70 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'TFS FALCON 4i (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     36610 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   9500000 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ?     1  1 ? ? cryoSPARC ?            
'IMAGE ACQUISITION'        ?     2  1 ? 1 ?         ?            
MASKING                    ?     3  1 1 1 ?         ?            
'CTF CORRECTION'           ?     4  1 ? ? cryoSPARC ?            
'LAYERLINE INDEXING'       ?     5  1 1 1 ?         ?            
'DIFFRACTION INDEXING'     ?     6  1 1 1 ?         ?            
'MODEL FITTING'            ?     7  1 1 ? ISOLDE    ?            
OTHER                      ?     8  1 1 1 ?         ?            
'INITIAL EULER ASSIGNMENT' ?     9  1 ? ? ?         ?            
'FINAL EULER ASSIGNMENT'   ?     10 1 ? ? ?         ?            
CLASSIFICATION             blush 11 1 ? ? RELION    5            
RECONSTRUCTION             ?     12 1 ? ? ?         ?            
'MODEL REFINEMENT'         ?     13 ? 1 ? PHENIX    1.20.1_4487: 
# 
_em_specimen.concentration           0.5 
_em_specimen.details                 'This sample was monodisperse' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'European Research Council (ERC)' 
_pdbx_audit_support.country                'European Union' 
_pdbx_audit_support.grant_number           101041298 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      ITasser 
_pdbx_initial_refinement_model.accession_code   ? 
# 
_atom_sites.entry_id                    9GSZ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
I 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N      . TRP A 1 78  ? 123.974 94.766  95.015  1.00 62.99  ? 69  TRP A N      1 
ATOM   2    C CA     . TRP A 1 78  ? 123.507 95.886  95.881  1.00 62.99  ? 69  TRP A CA     1 
ATOM   3    C C      . TRP A 1 78  ? 124.509 96.088  97.010  1.00 62.99  ? 69  TRP A C      1 
ATOM   4    O O      . TRP A 1 78  ? 125.193 97.109  97.068  1.00 62.99  ? 69  TRP A O      1 
ATOM   5    C CB     . TRP A 1 78  ? 122.107 95.596  96.428  1.00 62.99  ? 69  TRP A CB     1 
ATOM   6    C CG     . TRP A 1 78  ? 121.324 94.652  95.563  1.00 62.99  ? 69  TRP A CG     1 
ATOM   7    C CD1    . TRP A 1 78  ? 120.919 93.391  95.885  1.00 62.99  ? 69  TRP A CD1    1 
ATOM   8    C CD2    . TRP A 1 78  ? 120.868 94.889  94.225  1.00 62.99  ? 69  TRP A CD2    1 
ATOM   9    N NE1    . TRP A 1 78  ? 120.234 92.830  94.836  1.00 62.99  ? 69  TRP A NE1    1 
ATOM   10   C CE2    . TRP A 1 78  ? 120.189 93.730  93.804  1.00 62.99  ? 69  TRP A CE2    1 
ATOM   11   C CE3    . TRP A 1 78  ? 120.966 95.969  93.345  1.00 62.99  ? 69  TRP A CE3    1 
ATOM   12   C CZ2    . TRP A 1 78  ? 119.610 93.621  92.543  1.00 62.99  ? 69  TRP A CZ2    1 
ATOM   13   C CZ3    . TRP A 1 78  ? 120.390 95.860  92.093  1.00 62.99  ? 69  TRP A CZ3    1 
ATOM   14   C CH2    . TRP A 1 78  ? 119.721 94.695  91.704  1.00 62.99  ? 69  TRP A CH2    1 
ATOM   15   H H      . TRP A 1 78  ? 124.848 94.847  94.872  1.00 62.99  ? 69  TRP A H      1 
ATOM   16   H HA     . TRP A 1 78  ? 123.468 96.701  95.357  1.00 62.99  ? 69  TRP A HA     1 
ATOM   17   H HB2    . TRP A 1 78  ? 122.177 95.200  97.310  1.00 62.99  ? 69  TRP A HB2    1 
ATOM   18   H HB3    . TRP A 1 78  ? 121.612 96.429  96.479  1.00 62.99  ? 69  TRP A HB3    1 
ATOM   19   H HD1    . TRP A 1 78  ? 121.082 92.971  96.699  1.00 62.99  ? 69  TRP A HD1    1 
ATOM   20   H HE1    . TRP A 1 78  ? 119.890 92.042  94.827  1.00 62.99  ? 69  TRP A HE1    1 
ATOM   21   H HE3    . TRP A 1 78  ? 121.408 96.748  93.597  1.00 62.99  ? 69  TRP A HE3    1 
ATOM   22   H HZ2    . TRP A 1 78  ? 119.164 92.848  92.281  1.00 62.99  ? 69  TRP A HZ2    1 
ATOM   23   H HZ3    . TRP A 1 78  ? 120.448 96.573  91.499  1.00 62.99  ? 69  TRP A HZ3    1 
ATOM   24   H HH2    . TRP A 1 78  ? 119.343 94.650  90.855  1.00 62.99  ? 69  TRP A HH2    1 
ATOM   25   N N      . GLY A 1 79  ? 124.586 95.109  97.907  1.00 65.55  ? 70  GLY A N      1 
ATOM   26   C CA     . GLY A 1 79  ? 125.650 95.086  98.896  1.00 65.55  ? 70  GLY A CA     1 
ATOM   27   C C      . GLY A 1 79  ? 125.743 96.374  99.685  1.00 65.55  ? 70  GLY A C      1 
ATOM   28   O O      . GLY A 1 79  ? 124.738 96.978  100.074 1.00 65.55  ? 70  GLY A O      1 
ATOM   29   H H      . GLY A 1 79  ? 124.036 94.449  97.960  1.00 65.55  ? 70  GLY A H      1 
ATOM   30   H HA2    . GLY A 1 79  ? 125.499 94.357  99.517  1.00 65.55  ? 70  GLY A HA2    1 
ATOM   31   H HA3    . GLY A 1 79  ? 126.500 94.940  98.452  1.00 65.55  ? 70  GLY A HA3    1 
ATOM   32   N N      . TRP A 1 80  ? 126.981 96.820  99.899  1.00 63.34  ? 71  TRP A N      1 
ATOM   33   C CA     . TRP A 1 80  ? 127.243 97.970  100.755 1.00 63.34  ? 71  TRP A CA     1 
ATOM   34   C C      . TRP A 1 80  ? 126.624 99.245  100.201 1.00 63.34  ? 71  TRP A C      1 
ATOM   35   O O      . TRP A 1 80  ? 126.483 100.235 100.934 1.00 63.34  ? 71  TRP A O      1 
ATOM   36   C CB     . TRP A 1 80  ? 128.752 98.168  100.921 1.00 63.34  ? 71  TRP A CB     1 
ATOM   37   C CG     . TRP A 1 80  ? 129.552 96.898  101.114 1.00 63.34  ? 71  TRP A CG     1 
ATOM   38   C CD1    . TRP A 1 80  ? 129.914 95.997  100.150 1.00 63.34  ? 71  TRP A CD1    1 
ATOM   39   C CD2    . TRP A 1 80  ? 130.109 96.412  102.339 1.00 63.34  ? 71  TRP A CD2    1 
ATOM   40   N NE1    . TRP A 1 80  ? 130.646 94.979  100.703 1.00 63.34  ? 71  TRP A NE1    1 
ATOM   41   C CE2    . TRP A 1 80  ? 130.783 95.211  102.045 1.00 63.34  ? 71  TRP A CE2    1 
ATOM   42   C CE3    . TRP A 1 80  ? 130.101 96.875  103.657 1.00 63.34  ? 71  TRP A CE3    1 
ATOM   43   C CZ2    . TRP A 1 80  ? 131.438 94.467  103.019 1.00 63.34  ? 71  TRP A CZ2    1 
ATOM   44   C CZ3    . TRP A 1 80  ? 130.752 96.135  104.622 1.00 63.34  ? 71  TRP A CZ3    1 
ATOM   45   C CH2    . TRP A 1 80  ? 131.411 94.944  104.300 1.00 63.34  ? 71  TRP A CH2    1 
ATOM   46   H H      . TRP A 1 80  ? 127.674 96.479  99.532  1.00 63.34  ? 71  TRP A H      1 
ATOM   47   H HA     . TRP A 1 80  ? 126.863 97.805  101.633 1.00 63.34  ? 71  TRP A HA     1 
ATOM   48   H HB2    . TRP A 1 80  ? 129.093 98.610  100.127 1.00 63.34  ? 71  TRP A HB2    1 
ATOM   49   H HB3    . TRP A 1 80  ? 128.905 98.730  101.696 1.00 63.34  ? 71  TRP A HB3    1 
ATOM   50   H HD1    . TRP A 1 80  ? 129.689 96.062  99.250  1.00 63.34  ? 71  TRP A HD1    1 
ATOM   51   H HE1    . TRP A 1 80  ? 130.970 94.307  100.275 1.00 63.34  ? 71  TRP A HE1    1 
ATOM   52   H HE3    . TRP A 1 80  ? 129.664 97.665  103.880 1.00 63.34  ? 71  TRP A HE3    1 
ATOM   53   H HZ2    . TRP A 1 80  ? 131.877 93.675  102.807 1.00 63.34  ? 71  TRP A HZ2    1 
ATOM   54   H HZ3    . TRP A 1 80  ? 130.752 96.432  105.503 1.00 63.34  ? 71  TRP A HZ3    1 
ATOM   55   H HH2    . TRP A 1 80  ? 131.841 94.466  104.972 1.00 63.34  ? 71  TRP A HH2    1 
ATOM   56   N N      . LEU A 1 81  ? 126.251 99.246  98.921  1.00 64.49  ? 72  LEU A N      1 
ATOM   57   C CA     . LEU A 1 81  ? 125.678 100.446 98.331  1.00 64.49  ? 72  LEU A CA     1 
ATOM   58   C C      . LEU A 1 81  ? 124.421 100.882 99.065  1.00 64.49  ? 72  LEU A C      1 
ATOM   59   O O      . LEU A 1 81  ? 124.058 102.058 98.993  1.00 64.49  ? 72  LEU A O      1 
ATOM   60   C CB     . LEU A 1 81  ? 125.373 100.218 96.845  1.00 64.49  ? 72  LEU A CB     1 
ATOM   61   C CG     . LEU A 1 81  ? 124.779 101.398 96.065  1.00 64.49  ? 72  LEU A CG     1 
ATOM   62   C CD1    . LEU A 1 81  ? 125.598 102.660 96.271  1.00 64.49  ? 72  LEU A CD1    1 
ATOM   63   C CD2    . LEU A 1 81  ? 124.680 101.070 94.581  1.00 64.49  ? 72  LEU A CD2    1 
ATOM   64   H H      . LEU A 1 81  ? 126.316 98.578  98.384  1.00 64.49  ? 72  LEU A H      1 
ATOM   65   H HA     . LEU A 1 81  ? 126.327 101.163 98.399  1.00 64.49  ? 72  LEU A HA     1 
ATOM   66   H HB2    . LEU A 1 81  ? 126.200 99.972  96.403  1.00 64.49  ? 72  LEU A HB2    1 
ATOM   67   H HB3    . LEU A 1 81  ? 124.742 99.486  96.772  1.00 64.49  ? 72  LEU A HB3    1 
ATOM   68   H HG     . LEU A 1 81  ? 123.881 101.570 96.391  1.00 64.49  ? 72  LEU A HG     1 
ATOM   69   H HD11   . LEU A 1 81  ? 125.466 103.248 95.511  1.00 64.49  ? 72  LEU A HD11   1 
ATOM   70   H HD12   . LEU A 1 81  ? 125.302 103.098 97.084  1.00 64.49  ? 72  LEU A HD12   1 
ATOM   71   H HD13   . LEU A 1 81  ? 126.534 102.417 96.342  1.00 64.49  ? 72  LEU A HD13   1 
ATOM   72   H HD21   . LEU A 1 81  ? 124.274 101.819 94.117  1.00 64.49  ? 72  LEU A HD21   1 
ATOM   73   H HD22   . LEU A 1 81  ? 125.572 100.912 94.233  1.00 64.49  ? 72  LEU A HD22   1 
ATOM   74   H HD23   . LEU A 1 81  ? 124.135 100.276 94.466  1.00 64.49  ? 72  LEU A HD23   1 
ATOM   75   N N      . VAL A 1 82  ? 123.758 99.971  99.782  1.00 66.06  ? 73  VAL A N      1 
ATOM   76   C CA     . VAL A 1 82  ? 122.632 100.380 100.615 1.00 66.06  ? 73  VAL A CA     1 
ATOM   77   C C      . VAL A 1 82  ? 123.082 101.424 101.627 1.00 66.06  ? 73  VAL A C      1 
ATOM   78   O O      . VAL A 1 82  ? 122.499 102.512 101.726 1.00 66.06  ? 73  VAL A O      1 
ATOM   79   C CB     . VAL A 1 82  ? 122.013 99.154  101.311 1.00 66.06  ? 73  VAL A CB     1 
ATOM   80   C CG1    . VAL A 1 82  ? 120.907 99.578  102.257 1.00 66.06  ? 73  VAL A CG1    1 
ATOM   81   C CG2    . VAL A 1 82  ? 121.490 98.164  100.290 1.00 66.06  ? 73  VAL A CG2    1 
ATOM   82   H H      . VAL A 1 82  ? 123.934 99.130  99.800  1.00 66.06  ? 73  VAL A H      1 
ATOM   83   H HA     . VAL A 1 82  ? 121.957 100.785 100.046 1.00 66.06  ? 73  VAL A HA     1 
ATOM   84   H HB     . VAL A 1 82  ? 122.695 98.704  101.833 1.00 66.06  ? 73  VAL A HB     1 
ATOM   85   H HG11   . VAL A 1 82  ? 121.296 100.039 103.016 1.00 66.06  ? 73  VAL A HG11   1 
ATOM   86   H HG12   . VAL A 1 82  ? 120.434 98.790  102.564 1.00 66.06  ? 73  VAL A HG12   1 
ATOM   87   H HG13   . VAL A 1 82  ? 120.298 100.167 101.785 1.00 66.06  ? 73  VAL A HG13   1 
ATOM   88   H HG21   . VAL A 1 82  ? 120.851 98.619  99.719  1.00 66.06  ? 73  VAL A HG21   1 
ATOM   89   H HG22   . VAL A 1 82  ? 121.059 97.431  100.755 1.00 66.06  ? 73  VAL A HG22   1 
ATOM   90   H HG23   . VAL A 1 82  ? 122.231 97.827  99.763  1.00 66.06  ? 73  VAL A HG23   1 
ATOM   91   N N      . MET A 1 83  ? 124.151 101.125 102.367 1.00 67.48  ? 74  MET A N      1 
ATOM   92   C CA     . MET A 1 83  ? 124.695 102.084 103.321 1.00 67.48  ? 74  MET A CA     1 
ATOM   93   C C      . MET A 1 83  ? 125.240 103.313 102.606 1.00 67.48  ? 74  MET A C      1 
ATOM   94   O O      . MET A 1 83  ? 125.095 104.442 103.096 1.00 67.48  ? 74  MET A O      1 
ATOM   95   C CB     . MET A 1 83  ? 125.790 101.419 104.163 1.00 67.48  ? 74  MET A CB     1 
ATOM   96   C CG     . MET A 1 83  ? 126.296 102.260 105.334 1.00 67.48  ? 74  MET A CG     1 
ATOM   97   S SD     . MET A 1 83  ? 127.424 103.599 104.883 1.00 67.48  ? 74  MET A SD     1 
ATOM   98   C CE     . MET A 1 83  ? 128.875 102.680 104.375 1.00 67.48  ? 74  MET A CE     1 
ATOM   99   H H      . MET A 1 83  ? 124.576 100.379 102.331 1.00 67.48  ? 74  MET A H      1 
ATOM   100  H HA     . MET A 1 83  ? 123.986 102.362 103.922 1.00 67.48  ? 74  MET A HA     1 
ATOM   101  H HB2    . MET A 1 83  ? 125.439 100.592 104.528 1.00 67.48  ? 74  MET A HB2    1 
ATOM   102  H HB3    . MET A 1 83  ? 126.547 101.223 103.591 1.00 67.48  ? 74  MET A HB3    1 
ATOM   103  H HG2    . MET A 1 83  ? 125.535 102.655 105.787 1.00 67.48  ? 74  MET A HG2    1 
ATOM   104  H HG3    . MET A 1 83  ? 126.771 101.675 105.946 1.00 67.48  ? 74  MET A HG3    1 
ATOM   105  H HE1    . MET A 1 83  ? 129.582 103.305 104.150 1.00 67.48  ? 74  MET A HE1    1 
ATOM   106  H HE2    . MET A 1 83  ? 129.158 102.108 105.105 1.00 67.48  ? 74  MET A HE2    1 
ATOM   107  H HE3    . MET A 1 83  ? 128.651 102.141 103.600 1.00 67.48  ? 74  MET A HE3    1 
ATOM   108  N N      . LEU A 1 84  ? 125.872 103.114 101.449 1.00 65.30  ? 75  LEU A N      1 
ATOM   109  C CA     . LEU A 1 84  ? 126.442 104.252 100.735 1.00 65.30  ? 75  LEU A CA     1 
ATOM   110  C C      . LEU A 1 84  ? 125.360 105.251 100.337 1.00 65.30  ? 75  LEU A C      1 
ATOM   111  O O      . LEU A 1 84  ? 125.556 106.466 100.446 1.00 65.30  ? 75  LEU A O      1 
ATOM   112  C CB     . LEU A 1 84  ? 127.212 103.760 99.511  1.00 65.30  ? 75  LEU A CB     1 
ATOM   113  C CG     . LEU A 1 84  ? 128.082 104.780 98.775  1.00 65.30  ? 75  LEU A CG     1 
ATOM   114  C CD1    . LEU A 1 84  ? 129.038 105.479 99.726  1.00 65.30  ? 75  LEU A CD1    1 
ATOM   115  C CD2    . LEU A 1 84  ? 128.855 104.096 97.665  1.00 65.30  ? 75  LEU A CD2    1 
ATOM   116  H H      . LEU A 1 84  ? 125.982 102.353 101.064 1.00 65.30  ? 75  LEU A H      1 
ATOM   117  H HA     . LEU A 1 84  ? 127.061 104.708 101.326 1.00 65.30  ? 75  LEU A HA     1 
ATOM   118  H HB2    . LEU A 1 84  ? 127.798 103.043 99.800  1.00 65.30  ? 75  LEU A HB2    1 
ATOM   119  H HB3    . LEU A 1 84  ? 126.572 103.413 98.873  1.00 65.30  ? 75  LEU A HB3    1 
ATOM   120  H HG     . LEU A 1 84  ? 127.510 105.454 98.375  1.00 65.30  ? 75  LEU A HG     1 
ATOM   121  H HD11   . LEU A 1 84  ? 129.681 105.988 99.209  1.00 65.30  ? 75  LEU A HD11   1 
ATOM   122  H HD12   . LEU A 1 84  ? 128.532 106.072 100.302 1.00 65.30  ? 75  LEU A HD12   1 
ATOM   123  H HD13   . LEU A 1 84  ? 129.497 104.810 100.258 1.00 65.30  ? 75  LEU A HD13   1 
ATOM   124  H HD21   . LEU A 1 84  ? 129.393 104.757 97.202  1.00 65.30  ? 75  LEU A HD21   1 
ATOM   125  H HD22   . LEU A 1 84  ? 129.428 103.415 98.052  1.00 65.30  ? 75  LEU A HD22   1 
ATOM   126  H HD23   . LEU A 1 84  ? 128.228 103.688 97.048  1.00 65.30  ? 75  LEU A HD23   1 
ATOM   127  N N      . ALA A 1 85  ? 124.207 104.757 99.886  1.00 65.03  ? 76  ALA A N      1 
ATOM   128  C CA     . ALA A 1 85  ? 123.114 105.645 99.506  1.00 65.03  ? 76  ALA A CA     1 
ATOM   129  C C      . ALA A 1 85  ? 122.394 106.205 100.726 1.00 65.03  ? 76  ALA A C      1 
ATOM   130  O O      . ALA A 1 85  ? 121.882 107.330 100.680 1.00 65.03  ? 76  ALA A O      1 
ATOM   131  C CB     . ALA A 1 85  ? 122.129 104.905 98.605  1.00 65.03  ? 76  ALA A CB     1 
ATOM   132  H H      . ALA A 1 85  ? 124.033 103.920 99.799  1.00 65.03  ? 76  ALA A H      1 
ATOM   133  H HA     . ALA A 1 85  ? 123.468 106.394 99.001  1.00 65.03  ? 76  ALA A HA     1 
ATOM   134  H HB1    . ALA A 1 85  ? 122.589 104.601 97.806  1.00 65.03  ? 76  ALA A HB1    1 
ATOM   135  H HB2    . ALA A 1 85  ? 121.774 104.145 99.092  1.00 65.03  ? 76  ALA A HB2    1 
ATOM   136  H HB3    . ALA A 1 85  ? 121.412 105.511 98.363  1.00 65.03  ? 76  ALA A HB3    1 
ATOM   137  N N      . ALA A 1 86  ? 122.323 105.435 101.814 1.00 66.09  ? 77  ALA A N      1 
ATOM   138  C CA     . ALA A 1 86  ? 121.750 105.973 103.042 1.00 66.09  ? 77  ALA A CA     1 
ATOM   139  C C      . ALA A 1 86  ? 122.545 107.180 103.517 1.00 66.09  ? 77  ALA A C      1 
ATOM   140  O O      . ALA A 1 86  ? 121.972 108.161 104.012 1.00 66.09  ? 77  ALA A O      1 
ATOM   141  C CB     . ALA A 1 86  ? 121.715 104.895 104.122 1.00 66.09  ? 77  ALA A CB     1 
ATOM   142  H H      . ALA A 1 86  ? 122.588 104.618 101.865 1.00 66.09  ? 77  ALA A H      1 
ATOM   143  H HA     . ALA A 1 86  ? 120.839 106.256 102.868 1.00 66.09  ? 77  ALA A HA     1 
ATOM   144  H HB1    . ALA A 1 86  ? 121.169 104.156 103.811 1.00 66.09  ? 77  ALA A HB1    1 
ATOM   145  H HB2    . ALA A 1 86  ? 122.622 104.593 104.287 1.00 66.09  ? 77  ALA A HB2    1 
ATOM   146  H HB3    . ALA A 1 86  ? 121.336 105.270 104.933 1.00 66.09  ? 77  ALA A HB3    1 
ATOM   147  N N      . MET A 1 87  ? 123.871 107.116 103.388 1.00 66.36  ? 78  MET A N      1 
ATOM   148  C CA     . MET A 1 87  ? 124.695 108.279 103.693 1.00 66.36  ? 78  MET A CA     1 
ATOM   149  C C      . MET A 1 87  ? 124.228 109.491 102.900 1.00 66.36  ? 78  MET A C      1 
ATOM   150  O O      . MET A 1 87  ? 124.032 110.581 103.455 1.00 66.36  ? 78  MET A O      1 
ATOM   151  C CB     . MET A 1 87  ? 126.161 107.977 103.382 1.00 66.36  ? 78  MET A CB     1 
ATOM   152  C CG     . MET A 1 87  ? 127.096 109.169 103.566 1.00 66.36  ? 78  MET A CG     1 
ATOM   153  S SD     . MET A 1 87  ? 128.793 108.829 103.055 1.00 66.36  ? 78  MET A SD     1 
ATOM   154  C CE     . MET A 1 87  ? 128.618 108.805 101.272 1.00 66.36  ? 78  MET A CE     1 
ATOM   155  H H      . MET A 1 87  ? 124.309 106.422 103.131 1.00 66.36  ? 78  MET A H      1 
ATOM   156  H HA     . MET A 1 87  ? 124.625 108.476 104.639 1.00 66.36  ? 78  MET A HA     1 
ATOM   157  H HB2    . MET A 1 87  ? 126.464 107.271 103.975 1.00 66.36  ? 78  MET A HB2    1 
ATOM   158  H HB3    . MET A 1 87  ? 126.230 107.685 102.460 1.00 66.36  ? 78  MET A HB3    1 
ATOM   159  H HG2    . MET A 1 87  ? 126.780 109.914 103.034 1.00 66.36  ? 78  MET A HG2    1 
ATOM   160  H HG3    . MET A 1 87  ? 127.108 109.413 104.504 1.00 66.36  ? 78  MET A HG3    1 
ATOM   161  H HE1    . MET A 1 87  ? 127.960 108.135 101.029 1.00 66.36  ? 78  MET A HE1    1 
ATOM   162  H HE2    . MET A 1 87  ? 129.475 108.588 100.874 1.00 66.36  ? 78  MET A HE2    1 
ATOM   163  H HE3    . MET A 1 87  ? 128.324 109.680 100.973 1.00 66.36  ? 78  MET A HE3    1 
ATOM   164  N N      . TRP A 1 88  ? 124.047 109.315 101.589 1.00 64.45  ? 79  TRP A N      1 
ATOM   165  C CA     . TRP A 1 88  ? 123.647 110.434 100.744 1.00 64.45  ? 79  TRP A CA     1 
ATOM   166  C C      . TRP A 1 88  ? 122.291 110.977 101.164 1.00 64.45  ? 79  TRP A C      1 
ATOM   167  O O      . TRP A 1 88  ? 122.081 112.192 101.172 1.00 64.45  ? 79  TRP A O      1 
ATOM   168  C CB     . TRP A 1 88  ? 123.614 110.006 99.277  1.00 64.45  ? 79  TRP A CB     1 
ATOM   169  C CG     . TRP A 1 88  ? 123.178 111.103 98.365  1.00 64.45  ? 79  TRP A CG     1 
ATOM   170  C CD1    . TRP A 1 88  ? 121.899 111.450 98.056  1.00 64.45  ? 79  TRP A CD1    1 
ATOM   171  C CD2    . TRP A 1 88  ? 124.023 112.006 97.649  1.00 64.45  ? 79  TRP A CD2    1 
ATOM   172  N NE1    . TRP A 1 88  ? 121.892 112.513 97.192  1.00 64.45  ? 79  TRP A NE1    1 
ATOM   173  C CE2    . TRP A 1 88  ? 123.185 112.874 96.925  1.00 64.45  ? 79  TRP A CE2    1 
ATOM   174  C CE3    . TRP A 1 88  ? 125.406 112.166 97.548  1.00 64.45  ? 79  TRP A CE3    1 
ATOM   175  C CZ2    . TRP A 1 88  ? 123.684 113.886 96.111  1.00 64.45  ? 79  TRP A CZ2    1 
ATOM   176  C CZ3    . TRP A 1 88  ? 125.900 113.170 96.739  1.00 64.45  ? 79  TRP A CZ3    1 
ATOM   177  C CH2    . TRP A 1 88  ? 125.041 114.018 96.031  1.00 64.45  ? 79  TRP A CH2    1 
ATOM   178  H H      . TRP A 1 88  ? 124.148 108.569 101.173 1.00 64.45  ? 79  TRP A H      1 
ATOM   179  H HA     . TRP A 1 88  ? 124.297 111.148 100.834 1.00 64.45  ? 79  TRP A HA     1 
ATOM   180  H HB2    . TRP A 1 88  ? 124.503 109.728 99.007  1.00 64.45  ? 79  TRP A HB2    1 
ATOM   181  H HB3    . TRP A 1 88  ? 122.992 109.269 99.176  1.00 64.45  ? 79  TRP A HB3    1 
ATOM   182  H HD1    . TRP A 1 88  ? 121.139 111.028 98.387  1.00 64.45  ? 79  TRP A HD1    1 
ATOM   183  H HE1    . TRP A 1 88  ? 121.190 112.891 96.869  1.00 64.45  ? 79  TRP A HE1    1 
ATOM   184  H HE3    . TRP A 1 88  ? 125.984 111.607 98.016  1.00 64.45  ? 79  TRP A HE3    1 
ATOM   185  H HZ2    . TRP A 1 88  ? 123.115 114.450 95.638  1.00 64.45  ? 79  TRP A HZ2    1 
ATOM   186  H HZ3    . TRP A 1 88  ? 126.819 113.285 96.665  1.00 64.45  ? 79  TRP A HZ3    1 
ATOM   187  H HH2    . TRP A 1 88  ? 125.403 114.685 95.494  1.00 64.45  ? 79  TRP A HH2    1 
ATOM   188  N N      . CYS A 1 89  ? 121.351 110.093 101.497 1.00 64.14  ? 80  CYS A N      1 
ATOM   189  C CA     . CYS A 1 89  ? 120.023 110.547 101.903 1.00 64.14  ? 80  CYS A CA     1 
ATOM   190  C C      . CYS A 1 89  ? 120.095 111.387 103.173 1.00 64.14  ? 80  CYS A C      1 
ATOM   191  O O      . CYS A 1 89  ? 119.542 112.500 103.244 1.00 64.14  ? 80  CYS A O      1 
ATOM   192  C CB     . CYS A 1 89  ? 119.107 109.342 102.111 1.00 64.14  ? 80  CYS A CB     1 
ATOM   193  S SG     . CYS A 1 89  ? 117.516 109.742 102.862 1.00 64.14  ? 80  CYS A SG     1 
ATOM   194  H H      . CYS A 1 89  ? 121.455 109.239 101.497 1.00 64.14  ? 80  CYS A H      1 
ATOM   195  H HA     . CYS A 1 89  ? 119.645 111.096 101.198 1.00 64.14  ? 80  CYS A HA     1 
ATOM   196  H HB2    . CYS A 1 89  ? 118.933 108.930 101.251 1.00 64.14  ? 80  CYS A HB2    1 
ATOM   197  H HB3    . CYS A 1 89  ? 119.557 108.710 102.693 1.00 64.14  ? 80  CYS A HB3    1 
ATOM   198  H HG     . CYS A 1 89  ? 116.939 110.524 102.159 1.00 64.14  ? 80  CYS A HG     1 
ATOM   199  N N      . ASN A 1 90  ? 120.770 110.858 104.198 1.00 63.20  ? 81  ASN A N      1 
ATOM   200  C CA     . ASN A 1 90  ? 120.845 111.566 105.469 1.00 63.20  ? 81  ASN A CA     1 
ATOM   201  C C      . ASN A 1 90  ? 121.551 112.901 105.303 1.00 63.20  ? 81  ASN A C      1 
ATOM   202  O O      . ASN A 1 90  ? 121.158 113.899 105.917 1.00 63.20  ? 81  ASN A O      1 
ATOM   203  C CB     . ASN A 1 90  ? 121.560 110.710 106.511 1.00 63.20  ? 81  ASN A CB     1 
ATOM   204  C CG     . ASN A 1 90  ? 121.628 111.384 107.866 1.00 63.20  ? 81  ASN A CG     1 
ATOM   205  O OD1    . ASN A 1 90  ? 122.469 112.250 108.099 1.00 63.20  ? 81  ASN A OD1    1 
ATOM   206  N ND2    . ASN A 1 90  ? 120.741 110.987 108.770 1.00 63.20  ? 81  ASN A ND2    1 
ATOM   207  H H      . ASN A 1 90  ? 121.183 110.103 104.180 1.00 63.20  ? 81  ASN A H      1 
ATOM   208  H HA     . ASN A 1 90  ? 119.945 111.739 105.788 1.00 63.20  ? 81  ASN A HA     1 
ATOM   209  H HB2    . ASN A 1 90  ? 121.083 109.872 106.615 1.00 63.20  ? 81  ASN A HB2    1 
ATOM   210  H HB3    . ASN A 1 90  ? 122.468 110.543 106.213 1.00 63.20  ? 81  ASN A HB3    1 
ATOM   211  H HD21   . ASN A 1 90  ? 120.168 110.378 108.571 1.00 63.20  ? 81  ASN A HD21   1 
ATOM   212  H HD22   . ASN A 1 90  ? 120.739 111.340 109.554 1.00 63.20  ? 81  ASN A HD22   1 
ATOM   213  N N      . GLY A 1 91  ? 122.600 112.942 104.484 1.00 64.83  ? 82  GLY A N      1 
ATOM   214  C CA     . GLY A 1 91  ? 123.231 114.218 104.203 1.00 64.83  ? 82  GLY A CA     1 
ATOM   215  C C      . GLY A 1 91  ? 122.301 115.167 103.473 1.00 64.83  ? 82  GLY A C      1 
ATOM   216  O O      . GLY A 1 91  ? 122.151 116.328 103.856 1.00 64.83  ? 82  GLY A O      1 
ATOM   217  H H      . GLY A 1 91  ? 122.952 112.264 104.091 1.00 64.83  ? 82  GLY A H      1 
ATOM   218  H HA2    . GLY A 1 91  ? 123.506 114.633 105.036 1.00 64.83  ? 82  GLY A HA2    1 
ATOM   219  H HA3    . GLY A 1 91  ? 124.019 114.076 103.654 1.00 64.83  ? 82  GLY A HA3    1 
ATOM   220  N N      . SER A 1 92  ? 121.627 114.670 102.435 1.00 64.11  ? 83  SER A N      1 
ATOM   221  C CA     . SER A 1 92  ? 120.867 115.540 101.547 1.00 64.11  ? 83  SER A CA     1 
ATOM   222  C C      . SER A 1 92  ? 119.735 116.235 102.284 1.00 64.11  ? 83  SER A C      1 
ATOM   223  O O      . SER A 1 92  ? 119.469 117.419 102.049 1.00 64.11  ? 83  SER A O      1 
ATOM   224  C CB     . SER A 1 92  ? 120.319 114.730 100.374 1.00 64.11  ? 83  SER A CB     1 
ATOM   225  O OG     . SER A 1 92  ? 119.521 115.537 99.526  1.00 64.11  ? 83  SER A OG     1 
ATOM   226  H H      . SER A 1 92  ? 121.597 113.836 102.225 1.00 64.11  ? 83  SER A H      1 
ATOM   227  H HA     . SER A 1 92  ? 121.457 116.222 101.191 1.00 64.11  ? 83  SER A HA     1 
ATOM   228  H HB2    . SER A 1 92  ? 121.062 114.373 99.863  1.00 64.11  ? 83  SER A HB2    1 
ATOM   229  H HB3    . SER A 1 92  ? 119.775 114.004 100.719 1.00 64.11  ? 83  SER A HB3    1 
ATOM   230  H HG     . SER A 1 92  ? 118.823 115.777 99.927  1.00 64.11  ? 83  SER A HG     1 
ATOM   231  N N      . VAL A 1 93  ? 119.046 115.522 103.171 1.00 61.16  ? 84  VAL A N      1 
ATOM   232  C CA     . VAL A 1 93  ? 117.918 116.141 103.867 1.00 61.16  ? 84  VAL A CA     1 
ATOM   233  C C      . VAL A 1 93  ? 118.411 117.193 104.859 1.00 61.16  ? 84  VAL A C      1 
ATOM   234  O O      . VAL A 1 93  ? 118.096 118.390 104.754 1.00 61.16  ? 84  VAL A O      1 
ATOM   235  C CB     . VAL A 1 93  ? 117.061 115.071 104.562 1.00 61.16  ? 84  VAL A CB     1 
ATOM   236  C CG1    . VAL A 1 93  ? 116.041 115.723 105.476 1.00 61.16  ? 84  VAL A CG1    1 
ATOM   237  C CG2    . VAL A 1 93  ? 116.373 114.200 103.529 1.00 61.16  ? 84  VAL A CG2    1 
ATOM   238  H H      . VAL A 1 93  ? 119.204 114.704 103.385 1.00 61.16  ? 84  VAL A H      1 
ATOM   239  H HA     . VAL A 1 93  ? 117.357 116.590 103.215 1.00 61.16  ? 84  VAL A HA     1 
ATOM   240  H HB     . VAL A 1 93  ? 117.634 114.505 105.103 1.00 61.16  ? 84  VAL A HB     1 
ATOM   241  H HG11   . VAL A 1 93  ? 116.474 115.971 106.308 1.00 61.16  ? 84  VAL A HG11   1 
ATOM   242  H HG12   . VAL A 1 93  ? 115.686 116.513 105.038 1.00 61.16  ? 84  VAL A HG12   1 
ATOM   243  H HG13   . VAL A 1 93  ? 115.325 115.093 105.653 1.00 61.16  ? 84  VAL A HG13   1 
ATOM   244  H HG21   . VAL A 1 93  ? 116.460 113.271 103.792 1.00 61.16  ? 84  VAL A HG21   1 
ATOM   245  H HG22   . VAL A 1 93  ? 116.792 114.340 102.666 1.00 61.16  ? 84  VAL A HG22   1 
ATOM   246  H HG23   . VAL A 1 93  ? 115.435 114.443 103.484 1.00 61.16  ? 84  VAL A HG23   1 
ATOM   247  N N      . PHE A 1 94  ? 119.206 116.763 105.836 1.00 61.25  ? 85  PHE A N      1 
ATOM   248  C CA     . PHE A 1 94  ? 119.527 117.632 106.957 1.00 61.25  ? 85  PHE A CA     1 
ATOM   249  C C      . PHE A 1 94  ? 120.559 118.700 106.624 1.00 61.25  ? 85  PHE A C      1 
ATOM   250  O O      . PHE A 1 94  ? 120.552 119.751 107.269 1.00 61.25  ? 85  PHE A O      1 
ATOM   251  C CB     . PHE A 1 94  ? 119.993 116.794 108.145 1.00 61.25  ? 85  PHE A CB     1 
ATOM   252  C CG     . PHE A 1 94  ? 118.893 115.992 108.774 1.00 61.25  ? 85  PHE A CG     1 
ATOM   253  C CD1    . PHE A 1 94  ? 117.795 116.624 109.327 1.00 61.25  ? 85  PHE A CD1    1 
ATOM   254  C CD2    . PHE A 1 94  ? 118.953 114.612 108.807 1.00 61.25  ? 85  PHE A CD2    1 
ATOM   255  C CE1    . PHE A 1 94  ? 116.778 115.895 109.902 1.00 61.25  ? 85  PHE A CE1    1 
ATOM   256  C CE2    . PHE A 1 94  ? 117.937 113.877 109.384 1.00 61.25  ? 85  PHE A CE2    1 
ATOM   257  C CZ     . PHE A 1 94  ? 116.848 114.521 109.932 1.00 61.25  ? 85  PHE A CZ     1 
ATOM   258  H H      . PHE A 1 94  ? 119.568 115.984 105.869 1.00 61.25  ? 85  PHE A H      1 
ATOM   259  H HA     . PHE A 1 94  ? 118.718 118.094 107.224 1.00 61.25  ? 85  PHE A HA     1 
ATOM   260  H HB2    . PHE A 1 94  ? 120.678 116.175 107.843 1.00 61.25  ? 85  PHE A HB2    1 
ATOM   261  H HB3    . PHE A 1 94  ? 120.357 117.385 108.823 1.00 61.25  ? 85  PHE A HB3    1 
ATOM   262  H HD1    . PHE A 1 94  ? 117.742 117.552 109.309 1.00 61.25  ? 85  PHE A HD1    1 
ATOM   263  H HD2    . PHE A 1 94  ? 119.685 114.173 108.439 1.00 61.25  ? 85  PHE A HD2    1 
ATOM   264  H HE1    . PHE A 1 94  ? 116.045 116.331 110.272 1.00 61.25  ? 85  PHE A HE1    1 
ATOM   265  H HE2    . PHE A 1 94  ? 117.987 112.948 109.403 1.00 61.25  ? 85  PHE A HE2    1 
ATOM   266  H HZ     . PHE A 1 94  ? 116.162 114.028 110.322 1.00 61.25  ? 85  PHE A HZ     1 
ATOM   267  N N      . GLY A 1 95  ? 121.429 118.493 105.632 1.00 61.64  ? 86  GLY A N      1 
ATOM   268  C CA     . GLY A 1 95  ? 122.309 119.571 105.226 1.00 61.64  ? 86  GLY A CA     1 
ATOM   269  C C      . GLY A 1 95  ? 121.537 120.780 104.741 1.00 61.64  ? 86  GLY A C      1 
ATOM   270  O O      . GLY A 1 95  ? 121.846 121.915 105.107 1.00 61.64  ? 86  GLY A O      1 
ATOM   271  H H      . GLY A 1 95  ? 121.520 117.759 105.194 1.00 61.64  ? 86  GLY A H      1 
ATOM   272  H HA2    . GLY A 1 95  ? 122.861 119.838 105.978 1.00 61.64  ? 86  GLY A HA2    1 
ATOM   273  H HA3    . GLY A 1 95  ? 122.887 119.265 104.510 1.00 61.64  ? 86  GLY A HA3    1 
ATOM   274  N N      . ILE A 1 96  ? 120.511 120.554 103.921 1.00 62.16  ? 87  ILE A N      1 
ATOM   275  C CA     . ILE A 1 96  ? 119.651 121.652 103.492 1.00 62.16  ? 87  ILE A CA     1 
ATOM   276  C C      . ILE A 1 96  ? 118.882 122.215 104.680 1.00 62.16  ? 87  ILE A C      1 
ATOM   277  O O      . ILE A 1 96  ? 118.787 123.438 104.862 1.00 62.16  ? 87  ILE A O      1 
ATOM   278  C CB     . ILE A 1 96  ? 118.700 121.183 102.378 1.00 62.16  ? 87  ILE A CB     1 
ATOM   279  C CG1    . ILE A 1 96  ? 119.501 120.651 101.188 1.00 62.16  ? 87  ILE A CG1    1 
ATOM   280  C CG2    . ILE A 1 96  ? 117.790 122.326 101.947 1.00 62.16  ? 87  ILE A CG2    1 
ATOM   281  C CD1    . ILE A 1 96  ? 118.653 120.024 100.102 1.00 62.16  ? 87  ILE A CD1    1 
ATOM   282  H H      . ILE A 1 96  ? 120.294 119.785 103.605 1.00 62.16  ? 87  ILE A H      1 
ATOM   283  H HA     . ILE A 1 96  ? 120.205 122.362 103.133 1.00 62.16  ? 87  ILE A HA     1 
ATOM   284  H HB     . ILE A 1 96  ? 118.148 120.465 102.726 1.00 62.16  ? 87  ILE A HB     1 
ATOM   285  H HG12   . ILE A 1 96  ? 119.993 121.386 100.790 1.00 62.16  ? 87  ILE A HG12   1 
ATOM   286  H HG13   . ILE A 1 96  ? 120.120 119.974 101.501 1.00 62.16  ? 87  ILE A HG13   1 
ATOM   287  H HG21   . ILE A 1 96  ? 117.187 122.547 102.674 1.00 62.16  ? 87  ILE A HG21   1 
ATOM   288  H HG22   . ILE A 1 96  ? 117.277 122.051 101.172 1.00 62.16  ? 87  ILE A HG22   1 
ATOM   289  H HG23   . ILE A 1 96  ? 118.336 123.096 101.724 1.00 62.16  ? 87  ILE A HG23   1 
ATOM   290  H HD11   . ILE A 1 96  ? 119.230 119.532 99.497  1.00 62.16  ? 87  ILE A HD11   1 
ATOM   291  H HD12   . ILE A 1 96  ? 118.012 119.422 100.511 1.00 62.16  ? 87  ILE A HD12   1 
ATOM   292  H HD13   . ILE A 1 96  ? 118.187 120.724 99.619  1.00 62.16  ? 87  ILE A HD13   1 
ATOM   293  N N      . GLN A 1 97  ? 118.311 121.333 105.507 1.00 60.56  ? 88  GLN A N      1 
ATOM   294  C CA     . GLN A 1 97  ? 117.516 121.827 106.628 1.00 60.56  ? 88  GLN A CA     1 
ATOM   295  C C      . GLN A 1 97  ? 118.348 122.680 107.580 1.00 60.56  ? 88  GLN A C      1 
ATOM   296  O O      . GLN A 1 97  ? 117.798 123.541 108.277 1.00 60.56  ? 88  GLN A O      1 
ATOM   297  C CB     . GLN A 1 97  ? 116.875 120.662 107.380 1.00 60.56  ? 88  GLN A CB     1 
ATOM   298  C CG     . GLN A 1 97  ? 115.801 119.936 106.586 1.00 60.56  ? 88  GLN A CG     1 
ATOM   299  C CD     . GLN A 1 97  ? 114.663 120.848 106.171 1.00 60.56  ? 88  GLN A CD     1 
ATOM   300  O OE1    . GLN A 1 97  ? 114.519 121.954 106.688 1.00 60.56  ? 88  GLN A OE1    1 
ATOM   301  N NE2    . GLN A 1 97  ? 113.852 120.389 105.227 1.00 60.56  ? 88  GLN A NE2    1 
ATOM   302  H H      . GLN A 1 97  ? 118.366 120.477 105.442 1.00 60.56  ? 88  GLN A H      1 
ATOM   303  H HA     . GLN A 1 97  ? 116.810 122.391 106.280 1.00 60.56  ? 88  GLN A HA     1 
ATOM   304  H HB2    . GLN A 1 97  ? 117.564 120.018 107.606 1.00 60.56  ? 88  GLN A HB2    1 
ATOM   305  H HB3    . GLN A 1 97  ? 116.466 121.001 108.191 1.00 60.56  ? 88  GLN A HB3    1 
ATOM   306  H HG2    . GLN A 1 97  ? 116.198 119.568 105.782 1.00 60.56  ? 88  GLN A HG2    1 
ATOM   307  H HG3    . GLN A 1 97  ? 115.432 119.223 107.131 1.00 60.56  ? 88  GLN A HG3    1 
ATOM   308  H HE21   . GLN A 1 97  ? 113.984 119.610 104.887 1.00 60.56  ? 88  GLN A HE21   1 
ATOM   309  H HE22   . GLN A 1 97  ? 113.192 120.869 104.957 1.00 60.56  ? 88  GLN A HE22   1 
ATOM   310  N N      . ASN A 1 98  ? 119.663 122.462 107.628 1.00 61.13  ? 89  ASN A N      1 
ATOM   311  C CA     . ASN A 1 98  ? 120.536 123.249 108.490 1.00 61.13  ? 89  ASN A CA     1 
ATOM   312  C C      . ASN A 1 98  ? 121.141 124.454 107.785 1.00 61.13  ? 89  ASN A C      1 
ATOM   313  O O      . ASN A 1 98  ? 121.457 125.450 108.444 1.00 61.13  ? 89  ASN A O      1 
ATOM   314  C CB     . ASN A 1 98  ? 121.661 122.373 109.040 1.00 61.13  ? 89  ASN A CB     1 
ATOM   315  C CG     . ASN A 1 98  ? 121.165 121.358 110.041 1.00 61.13  ? 89  ASN A CG     1 
ATOM   316  O OD1    . ASN A 1 98  ? 121.169 120.157 109.778 1.00 61.13  ? 89  ASN A OD1    1 
ATOM   317  N ND2    . ASN A 1 98  ? 120.736 121.836 111.201 1.00 61.13  ? 89  ASN A ND2    1 
ATOM   318  H H      . ASN A 1 98  ? 120.072 121.861 107.169 1.00 61.13  ? 89  ASN A H      1 
ATOM   319  H HA     . ASN A 1 98  ? 120.020 123.577 109.244 1.00 61.13  ? 89  ASN A HA     1 
ATOM   320  H HB2    . ASN A 1 98  ? 122.079 121.895 108.307 1.00 61.13  ? 89  ASN A HB2    1 
ATOM   321  H HB3    . ASN A 1 98  ? 122.314 122.939 109.483 1.00 61.13  ? 89  ASN A HB3    1 
ATOM   322  H HD21   . ASN A 1 98  ? 120.750 122.682 111.348 1.00 61.13  ? 89  ASN A HD21   1 
ATOM   323  H HD22   . ASN A 1 98  ? 120.443 121.299 111.806 1.00 61.13  ? 89  ASN A HD22   1 
ATOM   324  N N      . ALA A 1 99  ? 121.319 124.393 106.469 1.00 61.35  ? 90  ALA A N      1 
ATOM   325  C CA     . ALA A 1 99  ? 121.760 125.554 105.711 1.00 61.35  ? 90  ALA A CA     1 
ATOM   326  C C      . ALA A 1 99  ? 120.627 126.532 105.445 1.00 61.35  ? 90  ALA A C      1 
ATOM   327  O O      . ALA A 1 99  ? 120.871 127.600 104.873 1.00 61.35  ? 90  ALA A O      1 
ATOM   328  C CB     . ALA A 1 99  ? 122.385 125.114 104.387 1.00 61.35  ? 90  ALA A CB     1 
ATOM   329  H H      . ALA A 1 99  ? 121.192 123.688 105.993 1.00 61.35  ? 90  ALA A H      1 
ATOM   330  H HA     . ALA A 1 99  ? 122.440 126.022 106.221 1.00 61.35  ? 90  ALA A HA     1 
ATOM   331  H HB1    . ALA A 1 99  ? 123.147 124.543 104.573 1.00 61.35  ? 90  ALA A HB1    1 
ATOM   332  H HB2    . ALA A 1 99  ? 122.671 125.900 103.897 1.00 61.35  ? 90  ALA A HB2    1 
ATOM   333  H HB3    . ALA A 1 99  ? 121.723 124.625 103.872 1.00 61.35  ? 90  ALA A HB3    1 
ATOM   334  N N      . CYS A 1 100 ? 119.404 126.182 105.845 1.00 60.19  ? 91  CYS A N      1 
ATOM   335  C CA     . CYS A 1 100 ? 118.242 127.055 105.700 1.00 60.19  ? 91  CYS A CA     1 
ATOM   336  C C      . CYS A 1 100 ? 118.549 128.531 105.939 1.00 60.19  ? 91  CYS A C      1 
ATOM   337  O O      . CYS A 1 100 ? 117.959 129.396 105.286 1.00 60.19  ? 91  CYS A O      1 
ATOM   338  C CB     . CYS A 1 100 ? 117.141 126.608 106.664 1.00 60.19  ? 91  CYS A CB     1 
ATOM   339  S SG     . CYS A 1 100 ? 115.719 127.716 106.728 1.00 60.19  ? 91  CYS A SG     1 
ATOM   340  H H      . CYS A 1 100 ? 119.217 125.427 106.211 1.00 60.19  ? 91  CYS A H      1 
ATOM   341  H HA     . CYS A 1 100 ? 117.899 126.967 104.797 1.00 60.19  ? 91  CYS A HA     1 
ATOM   342  H HB2    . CYS A 1 100 ? 116.822 125.735 106.387 1.00 60.19  ? 91  CYS A HB2    1 
ATOM   343  H HB3    . CYS A 1 100 ? 117.513 126.554 107.558 1.00 60.19  ? 91  CYS A HB3    1 
ATOM   344  H HG     . CYS A 1 100 ? 115.222 127.779 105.638 1.00 60.19  ? 91  CYS A HG     1 
ATOM   345  N N      . GLY A 1 101 ? 119.435 128.839 106.885 1.00 59.61  ? 92  GLY A N      1 
ATOM   346  C CA     . GLY A 1 101 ? 119.737 130.235 107.169 1.00 59.61  ? 92  GLY A CA     1 
ATOM   347  C C      . GLY A 1 101 ? 120.360 130.962 105.992 1.00 59.61  ? 92  GLY A C      1 
ATOM   348  O O      . GLY A 1 101 ? 120.074 132.140 105.751 1.00 59.61  ? 92  GLY A O      1 
ATOM   349  H H      . GLY A 1 101 ? 119.866 128.270 107.366 1.00 59.61  ? 92  GLY A H      1 
ATOM   350  H HA2    . GLY A 1 101 ? 118.918 130.695 107.414 1.00 59.61  ? 92  GLY A HA2    1 
ATOM   351  H HA3    . GLY A 1 101 ? 120.351 130.285 107.919 1.00 59.61  ? 92  GLY A HA3    1 
ATOM   352  N N      . VAL A 1 102 ? 121.242 130.281 105.257 1.00 62.22  ? 93  VAL A N      1 
ATOM   353  C CA     . VAL A 1 102 ? 121.894 130.921 104.120 1.00 62.22  ? 93  VAL A CA     1 
ATOM   354  C C      . VAL A 1 102 ? 120.881 131.230 103.029 1.00 62.22  ? 93  VAL A C      1 
ATOM   355  O O      . VAL A 1 102 ? 121.048 132.193 102.273 1.00 62.22  ? 93  VAL A O      1 
ATOM   356  C CB     . VAL A 1 102 ? 123.041 130.046 103.587 1.00 62.22  ? 93  VAL A CB     1 
ATOM   357  C CG1    . VAL A 1 102 ? 123.698 130.713 102.390 1.00 62.22  ? 93  VAL A CG1    1 
ATOM   358  C CG2    . VAL A 1 102 ? 124.063 129.790 104.679 1.00 62.22  ? 93  VAL A CG2    1 
ATOM   359  H H      . VAL A 1 102 ? 121.475 129.465 105.395 1.00 62.22  ? 93  VAL A H      1 
ATOM   360  H HA     . VAL A 1 102 ? 122.277 131.763 104.414 1.00 62.22  ? 93  VAL A HA     1 
ATOM   361  H HB     . VAL A 1 102 ? 122.684 129.192 103.300 1.00 62.22  ? 93  VAL A HB     1 
ATOM   362  H HG11   . VAL A 1 102 ? 123.096 130.669 101.630 1.00 62.22  ? 93  VAL A HG11   1 
ATOM   363  H HG12   . VAL A 1 102 ? 123.889 131.638 102.609 1.00 62.22  ? 93  VAL A HG12   1 
ATOM   364  H HG13   . VAL A 1 102 ? 124.521 130.244 102.182 1.00 62.22  ? 93  VAL A HG13   1 
ATOM   365  H HG21   . VAL A 1 102 ? 124.808 129.295 104.302 1.00 62.22  ? 93  VAL A HG21   1 
ATOM   366  H HG22   . VAL A 1 102 ? 124.373 130.641 105.026 1.00 62.22  ? 93  VAL A HG22   1 
ATOM   367  H HG23   . VAL A 1 102 ? 123.648 129.274 105.387 1.00 62.22  ? 93  VAL A HG23   1 
ATOM   368  N N      . LEU A 1 103 ? 119.839 130.409 102.897 1.00 63.16  ? 94  LEU A N      1 
ATOM   369  C CA     . LEU A 1 103 ? 118.718 130.790 102.046 1.00 63.16  ? 94  LEU A CA     1 
ATOM   370  C C      . LEU A 1 103 ? 117.990 131.994 102.627 1.00 63.16  ? 94  LEU A C      1 
ATOM   371  O O      . LEU A 1 103 ? 117.802 133.006 101.946 1.00 63.16  ? 94  LEU A O      1 
ATOM   372  C CB     . LEU A 1 103 ? 117.756 129.613 101.887 1.00 63.16  ? 94  LEU A CB     1 
ATOM   373  C CG     . LEU A 1 103 ? 118.292 128.402 101.133 1.00 63.16  ? 94  LEU A CG     1 
ATOM   374  C CD1    . LEU A 1 103 ? 117.352 127.222 101.295 1.00 63.16  ? 94  LEU A CD1    1 
ATOM   375  C CD2    . LEU A 1 103 ? 118.482 128.740 99.667  1.00 63.16  ? 94  LEU A CD2    1 
ATOM   376  H H      . LEU A 1 103 ? 119.759 129.644 103.281 1.00 63.16  ? 94  LEU A H      1 
ATOM   377  H HA     . LEU A 1 103 ? 119.050 131.033 101.168 1.00 63.16  ? 94  LEU A HA     1 
ATOM   378  H HB2    . LEU A 1 103 ? 117.498 129.310 102.772 1.00 63.16  ? 94  LEU A HB2    1 
ATOM   379  H HB3    . LEU A 1 103 ? 116.970 129.925 101.412 1.00 63.16  ? 94  LEU A HB3    1 
ATOM   380  H HG     . LEU A 1 103 ? 119.154 128.154 101.501 1.00 63.16  ? 94  LEU A HG     1 
ATOM   381  H HD11   . LEU A 1 103 ? 117.277 127.006 102.237 1.00 63.16  ? 94  LEU A HD11   1 
ATOM   382  H HD12   . LEU A 1 103 ? 117.712 126.464 100.809 1.00 63.16  ? 94  LEU A HD12   1 
ATOM   383  H HD13   . LEU A 1 103 ? 116.482 127.461 100.939 1.00 63.16  ? 94  LEU A HD13   1 
ATOM   384  H HD21   . LEU A 1 103 ? 119.181 129.408 99.584  1.00 63.16  ? 94  LEU A HD21   1 
ATOM   385  H HD22   . LEU A 1 103 ? 118.735 127.935 99.189  1.00 63.16  ? 94  LEU A HD22   1 
ATOM   386  H HD23   . LEU A 1 103 ? 117.648 129.086 99.313  1.00 63.16  ? 94  LEU A HD23   1 
ATOM   387  N N      . PHE A 1 104 ? 117.629 131.914 103.910 1.00 61.75  ? 95  PHE A N      1 
ATOM   388  C CA     . PHE A 1 104 ? 116.805 132.940 104.541 1.00 61.75  ? 95  PHE A CA     1 
ATOM   389  C C      . PHE A 1 104 ? 117.395 134.329 104.353 1.00 61.75  ? 95  PHE A C      1 
ATOM   390  O O      . PHE A 1 104 ? 116.666 135.294 104.089 1.00 61.75  ? 95  PHE A O      1 
ATOM   391  C CB     . PHE A 1 104 ? 116.654 132.615 106.030 1.00 61.75  ? 95  PHE A CB     1 
ATOM   392  C CG     . PHE A 1 104 ? 115.954 133.680 106.824 1.00 61.75  ? 95  PHE A CG     1 
ATOM   393  C CD1    . PHE A 1 104 ? 116.663 134.731 107.378 1.00 61.75  ? 95  PHE A CD1    1 
ATOM   394  C CD2    . PHE A 1 104 ? 114.591 133.617 107.039 1.00 61.75  ? 95  PHE A CD2    1 
ATOM   395  C CE1    . PHE A 1 104 ? 116.023 135.705 108.115 1.00 61.75  ? 95  PHE A CE1    1 
ATOM   396  C CE2    . PHE A 1 104 ? 113.948 134.589 107.775 1.00 61.75  ? 95  PHE A CE2    1 
ATOM   397  C CZ     . PHE A 1 104 ? 114.666 135.633 108.313 1.00 61.75  ? 95  PHE A CZ     1 
ATOM   398  H H      . PHE A 1 104 ? 117.850 131.270 104.435 1.00 61.75  ? 95  PHE A H      1 
ATOM   399  H HA     . PHE A 1 104 ? 115.923 132.930 104.139 1.00 61.75  ? 95  PHE A HA     1 
ATOM   400  H HB2    . PHE A 1 104 ? 116.142 131.796 106.120 1.00 61.75  ? 95  PHE A HB2    1 
ATOM   401  H HB3    . PHE A 1 104 ? 117.537 132.494 106.412 1.00 61.75  ? 95  PHE A HB3    1 
ATOM   402  H HD1    . PHE A 1 104 ? 117.582 134.786 107.245 1.00 61.75  ? 95  PHE A HD1    1 
ATOM   403  H HD2    . PHE A 1 104 ? 114.100 132.915 106.677 1.00 61.75  ? 95  PHE A HD2    1 
ATOM   404  H HE1    . PHE A 1 104 ? 116.510 136.410 108.478 1.00 61.75  ? 95  PHE A HE1    1 
ATOM   405  H HE2    . PHE A 1 104 ? 113.029 134.539 107.909 1.00 61.75  ? 95  PHE A HE2    1 
ATOM   406  H HZ     . PHE A 1 104 ? 114.233 136.289 108.811 1.00 61.75  ? 95  PHE A HZ     1 
ATOM   407  N N      . VAL A 1 105 ? 118.716 134.452 104.486 1.00 62.57  ? 96  VAL A N      1 
ATOM   408  C CA     . VAL A 1 105 ? 119.328 135.780 104.476 1.00 62.57  ? 96  VAL A CA     1 
ATOM   409  C C      . VAL A 1 105 ? 119.009 136.510 103.177 1.00 62.57  ? 96  VAL A C      1 
ATOM   410  O O      . VAL A 1 105 ? 118.753 137.720 103.178 1.00 62.57  ? 96  VAL A O      1 
ATOM   411  C CB     . VAL A 1 105 ? 120.847 135.682 104.710 1.00 62.57  ? 96  VAL A CB     1 
ATOM   412  C CG1    . VAL A 1 105 ? 121.516 134.931 103.578 1.00 62.57  ? 96  VAL A CG1    1 
ATOM   413  C CG2    . VAL A 1 105 ? 121.448 137.073 104.860 1.00 62.57  ? 96  VAL A CG2    1 
ATOM   414  H H      . VAL A 1 105 ? 119.268 133.800 104.581 1.00 62.57  ? 96  VAL A H      1 
ATOM   415  H HA     . VAL A 1 105 ? 118.952 136.299 105.204 1.00 62.57  ? 96  VAL A HA     1 
ATOM   416  H HB     . VAL A 1 105 ? 121.010 135.194 105.532 1.00 62.57  ? 96  VAL A HB     1 
ATOM   417  H HG11   . VAL A 1 105 ? 122.433 134.734 103.827 1.00 62.57  ? 96  VAL A HG11   1 
ATOM   418  H HG12   . VAL A 1 105 ? 121.030 134.109 103.429 1.00 62.57  ? 96  VAL A HG12   1 
ATOM   419  H HG13   . VAL A 1 105 ? 121.500 135.477 102.777 1.00 62.57  ? 96  VAL A HG13   1 
ATOM   420  H HG21   . VAL A 1 105 ? 122.372 136.987 105.145 1.00 62.57  ? 96  VAL A HG21   1 
ATOM   421  H HG22   . VAL A 1 105 ? 121.408 137.530 104.005 1.00 62.57  ? 96  VAL A HG22   1 
ATOM   422  H HG23   . VAL A 1 105 ? 120.942 137.566 105.524 1.00 62.57  ? 96  VAL A HG23   1 
ATOM   423  N N      . SER A 1 106 ? 119.022 135.795 102.049 1.00 63.82  ? 97  SER A N      1 
ATOM   424  C CA     . SER A 1 106 ? 118.730 136.407 100.757 1.00 63.82  ? 97  SER A CA     1 
ATOM   425  C C      . SER A 1 106 ? 117.251 136.352 100.403 1.00 63.82  ? 97  SER A C      1 
ATOM   426  O O      . SER A 1 106 ? 116.760 137.223 99.674  1.00 63.82  ? 97  SER A O      1 
ATOM   427  C CB     . SER A 1 106 ? 119.538 135.721 99.652  1.00 63.82  ? 97  SER A CB     1 
ATOM   428  O OG     . SER A 1 106 ? 119.156 134.366 99.512  1.00 63.82  ? 97  SER A OG     1 
ATOM   429  H H      . SER A 1 106 ? 119.198 134.954 102.009 1.00 63.82  ? 97  SER A H      1 
ATOM   430  H HA     . SER A 1 106 ? 118.995 137.340 100.783 1.00 63.82  ? 97  SER A HA     1 
ATOM   431  H HB2    . SER A 1 106 ? 119.380 136.182 98.813  1.00 63.82  ? 97  SER A HB2    1 
ATOM   432  H HB3    . SER A 1 106 ? 120.480 135.761 99.880  1.00 63.82  ? 97  SER A HB3    1 
ATOM   433  H HG     . SER A 1 106 ? 119.608 134.001 98.906  1.00 63.82  ? 97  SER A HG     1 
ATOM   434  N N      . MET A 1 107 ? 116.535 135.340 100.892 1.00 63.09  ? 98  MET A N      1 
ATOM   435  C CA     . MET A 1 107 ? 115.095 135.286 100.689 1.00 63.09  ? 98  MET A CA     1 
ATOM   436  C C      . MET A 1 107 ? 114.423 136.508 101.284 1.00 63.09  ? 98  MET A C      1 
ATOM   437  O O      . MET A 1 107 ? 113.466 137.036 100.709 1.00 63.09  ? 98  MET A O      1 
ATOM   438  C CB     . MET A 1 107 ? 114.531 134.008 101.312 1.00 63.09  ? 98  MET A CB     1 
ATOM   439  C CG     . MET A 1 107 ? 113.040 133.813 101.117 1.00 63.09  ? 98  MET A CG     1 
ATOM   440  S SD     . MET A 1 107 ? 112.409 132.409 102.053 1.00 63.09  ? 98  MET A SD     1 
ATOM   441  C CE     . MET A 1 107 ? 113.362 131.072 101.343 1.00 63.09  ? 98  MET A CE     1 
ATOM   442  H H      . MET A 1 107 ? 116.858 134.681 101.340 1.00 63.09  ? 98  MET A H      1 
ATOM   443  H HA     . MET A 1 107 ? 114.914 135.259 99.736  1.00 63.09  ? 98  MET A HA     1 
ATOM   444  H HB2    . MET A 1 107 ? 114.983 133.249 100.913 1.00 63.09  ? 98  MET A HB2    1 
ATOM   445  H HB3    . MET A 1 107 ? 114.703 134.026 102.266 1.00 63.09  ? 98  MET A HB3    1 
ATOM   446  H HG2    . MET A 1 107 ? 112.568 134.606 101.416 1.00 63.09  ? 98  MET A HG2    1 
ATOM   447  H HG3    . MET A 1 107 ? 112.860 133.654 100.177 1.00 63.09  ? 98  MET A HG3    1 
ATOM   448  H HE1    . MET A 1 107 ? 113.030 130.229 101.690 1.00 63.09  ? 98  MET A HE1    1 
ATOM   449  H HE2    . MET A 1 107 ? 113.265 131.094 100.378 1.00 63.09  ? 98  MET A HE2    1 
ATOM   450  H HE3    . MET A 1 107 ? 114.294 131.185 101.585 1.00 63.09  ? 98  MET A HE3    1 
ATOM   451  N N      . LEU A 1 108 ? 114.910 136.974 102.433 1.00 66.40  ? 99  LEU A N      1 
ATOM   452  C CA     . LEU A 1 108 ? 114.362 138.193 103.013 1.00 66.40  ? 99  LEU A CA     1 
ATOM   453  C C      . LEU A 1 108 ? 114.596 139.387 102.098 1.00 66.40  ? 99  LEU A C      1 
ATOM   454  O O      . LEU A 1 108 ? 113.711 140.234 101.938 1.00 66.40  ? 99  LEU A O      1 
ATOM   455  C CB     . LEU A 1 108 ? 114.977 138.439 104.389 1.00 66.40  ? 99  LEU A CB     1 
ATOM   456  C CG     . LEU A 1 108 ? 114.493 139.683 105.130 1.00 66.40  ? 99  LEU A CG     1 
ATOM   457  C CD1    . LEU A 1 108 ? 112.985 139.673 105.269 1.00 66.40  ? 99  LEU A CD1    1 
ATOM   458  C CD2    . LEU A 1 108 ? 115.153 139.767 106.493 1.00 66.40  ? 99  LEU A CD2    1 
ATOM   459  H H      . LEU A 1 108 ? 115.545 136.612 102.886 1.00 66.40  ? 99  LEU A H      1 
ATOM   460  H HA     . LEU A 1 108 ? 113.404 138.081 103.124 1.00 66.40  ? 99  LEU A HA     1 
ATOM   461  H HB2    . LEU A 1 108 ? 114.783 137.672 104.951 1.00 66.40  ? 99  LEU A HB2    1 
ATOM   462  H HB3    . LEU A 1 108 ? 115.938 138.524 104.282 1.00 66.40  ? 99  LEU A HB3    1 
ATOM   463  H HG     . LEU A 1 108 ? 114.743 140.473 104.626 1.00 66.40  ? 99  LEU A HG     1 
ATOM   464  H HD11   . LEU A 1 108 ? 112.719 140.398 105.855 1.00 66.40  ? 99  LEU A HD11   1 
ATOM   465  H HD12   . LEU A 1 108 ? 112.586 139.793 104.393 1.00 66.40  ? 99  LEU A HD12   1 
ATOM   466  H HD13   . LEU A 1 108 ? 112.708 138.824 105.647 1.00 66.40  ? 99  LEU A HD13   1 
ATOM   467  H HD21   . LEU A 1 108 ? 114.909 138.984 107.011 1.00 66.40  ? 99  LEU A HD21   1 
ATOM   468  H HD22   . LEU A 1 108 ? 114.847 140.570 106.943 1.00 66.40  ? 99  LEU A HD22   1 
ATOM   469  H HD23   . LEU A 1 108 ? 116.115 139.800 106.375 1.00 66.40  ? 99  LEU A HD23   1 
ATOM   470  N N      . GLU A 1 109 ? 115.781 139.472 101.489 1.00 68.44  ? 100 GLU A N      1 
ATOM   471  C CA     . GLU A 1 109 ? 116.088 140.612 100.630 1.00 68.44  ? 100 GLU A CA     1 
ATOM   472  C C      . GLU A 1 109 ? 115.246 140.597 99.362  1.00 68.44  ? 100 GLU A C      1 
ATOM   473  O O      . GLU A 1 109 ? 114.709 141.633 98.955  1.00 68.44  ? 100 GLU A O      1 
ATOM   474  C CB     . GLU A 1 109 ? 117.574 140.620 100.275 1.00 68.44  ? 100 GLU A CB     1 
ATOM   475  C CG     . GLU A 1 109 ? 118.494 140.946 101.437 1.00 68.44  ? 100 GLU A CG     1 
ATOM   476  C CD     . GLU A 1 109 ? 119.953 140.963 101.030 1.00 68.44  ? 100 GLU A CD     1 
ATOM   477  O OE1    . GLU A 1 109 ? 120.254 140.569 99.885  1.00 68.44  ? 100 GLU A OE1    1 
ATOM   478  O OE2    . GLU A 1 109 ? 120.799 141.371 101.854 1.00 68.44  ? 100 GLU A OE2    1 
ATOM   479  H H      . GLU A 1 109 ? 116.412 138.891 101.554 1.00 68.44  ? 100 GLU A H      1 
ATOM   480  H HA     . GLU A 1 109 ? 115.890 141.430 101.111 1.00 68.44  ? 100 GLU A HA     1 
ATOM   481  H HB2    . GLU A 1 109 ? 117.819 139.743 99.943  1.00 68.44  ? 100 GLU A HB2    1 
ATOM   482  H HB3    . GLU A 1 109 ? 117.724 141.284 99.584  1.00 68.44  ? 100 GLU A HB3    1 
ATOM   483  H HG2    . GLU A 1 109 ? 118.267 141.822 101.786 1.00 68.44  ? 100 GLU A HG2    1 
ATOM   484  H HG3    . GLU A 1 109 ? 118.382 140.273 102.127 1.00 68.44  ? 100 GLU A HG3    1 
ATOM   485  N N      . THR A 1 110 ? 115.127 139.441 98.718  1.00 67.07  ? 101 THR A N      1 
ATOM   486  C CA     . THR A 1 110 ? 114.351 139.363 97.489  1.00 67.07  ? 101 THR A CA     1 
ATOM   487  C C      . THR A 1 110 ? 112.872 139.568 97.792  1.00 67.07  ? 101 THR A C      1 
ATOM   488  O O      . THR A 1 110 ? 112.364 139.111 98.820  1.00 67.07  ? 101 THR A O      1 
ATOM   489  C CB     . THR A 1 110 ? 114.569 138.018 96.801  1.00 67.07  ? 101 THR A CB     1 
ATOM   490  O OG1    . THR A 1 110 ? 115.971 137.728 96.750  1.00 67.07  ? 101 THR A OG1    1 
ATOM   491  C CG2    . THR A 1 110 ? 114.022 138.052 95.386  1.00 67.07  ? 101 THR A CG2    1 
ATOM   492  H H      . THR A 1 110 ? 115.480 138.698 98.969  1.00 67.07  ? 101 THR A H      1 
ATOM   493  H HA     . THR A 1 110 ? 114.638 140.064 96.884  1.00 67.07  ? 101 THR A HA     1 
ATOM   494  H HB     . THR A 1 110 ? 114.110 137.321 97.295  1.00 67.07  ? 101 THR A HB     1 
ATOM   495  H HG1    . THR A 1 110 ? 116.271 137.614 97.526  1.00 67.07  ? 101 THR A HG1    1 
ATOM   496  H HG21   . THR A 1 110 ? 114.070 137.167 94.991  1.00 67.07  ? 101 THR A HG21   1 
ATOM   497  H HG22   . THR A 1 110 ? 113.098 138.344 95.389  1.00 67.07  ? 101 THR A HG22   1 
ATOM   498  H HG23   . THR A 1 110 ? 114.542 138.666 94.845  1.00 67.07  ? 101 THR A HG23   1 
ATOM   499  N N      . PHE A 1 111 ? 112.183 140.252 96.881  1.00 68.14  ? 102 PHE A N      1 
ATOM   500  C CA     . PHE A 1 111 ? 110.790 140.663 97.068  1.00 68.14  ? 102 PHE A CA     1 
ATOM   501  C C      . PHE A 1 111 ? 110.548 141.124 98.504  1.00 68.14  ? 102 PHE A C      1 
ATOM   502  O O      . PHE A 1 111 ? 109.623 140.684 99.187  1.00 68.14  ? 102 PHE A O      1 
ATOM   503  C CB     . PHE A 1 111 ? 109.819 139.547 96.670  1.00 68.14  ? 102 PHE A CB     1 
ATOM   504  C CG     . PHE A 1 111 ? 110.126 138.211 97.284  1.00 68.14  ? 102 PHE A CG     1 
ATOM   505  C CD1    . PHE A 1 111 ? 109.658 137.884 98.543  1.00 68.14  ? 102 PHE A CD1    1 
ATOM   506  C CD2    . PHE A 1 111 ? 110.875 137.277 96.595  1.00 68.14  ? 102 PHE A CD2    1 
ATOM   507  C CE1    . PHE A 1 111 ? 109.939 136.656 99.103  1.00 68.14  ? 102 PHE A CE1    1 
ATOM   508  C CE2    . PHE A 1 111 ? 111.157 136.049 97.152  1.00 68.14  ? 102 PHE A CE2    1 
ATOM   509  C CZ     . PHE A 1 111 ? 110.688 135.738 98.406  1.00 68.14  ? 102 PHE A CZ     1 
ATOM   510  H H      . PHE A 1 111 ? 112.509 140.497 96.124  1.00 68.14  ? 102 PHE A H      1 
ATOM   511  H HA     . PHE A 1 111 ? 110.615 141.420 96.488  1.00 68.14  ? 102 PHE A HA     1 
ATOM   512  H HB2    . PHE A 1 111 ? 108.924 139.800 96.945  1.00 68.14  ? 102 PHE A HB2    1 
ATOM   513  H HB3    . PHE A 1 111 ? 109.846 139.441 95.706  1.00 68.14  ? 102 PHE A HB3    1 
ATOM   514  H HD1    . PHE A 1 111 ? 109.150 138.500 99.020  1.00 68.14  ? 102 PHE A HD1    1 
ATOM   515  H HD2    . PHE A 1 111 ? 111.196 137.481 95.746  1.00 68.14  ? 102 PHE A HD2    1 
ATOM   516  H HE1    . PHE A 1 111 ? 109.621 136.447 99.951  1.00 68.14  ? 102 PHE A HE1    1 
ATOM   517  H HE2    . PHE A 1 111 ? 111.664 135.430 96.678  1.00 68.14  ? 102 PHE A HE2    1 
ATOM   518  H HZ     . PHE A 1 111 ? 110.878 134.909 98.782  1.00 68.14  ? 102 PHE A HZ     1 
ATOM   519  N N      . GLY A 1 112 ? 111.405 142.039 98.960  1.00 70.43  ? 103 GLY A N      1 
ATOM   520  C CA     . GLY A 1 112 ? 111.279 142.582 100.294 1.00 70.43  ? 103 GLY A CA     1 
ATOM   521  C C      . GLY A 1 112 ? 110.179 143.620 100.398 1.00 70.43  ? 103 GLY A C      1 
ATOM   522  O O      . GLY A 1 112 ? 109.599 144.064 99.408  1.00 70.43  ? 103 GLY A O      1 
ATOM   523  H H      . GLY A 1 112 ? 112.067 142.355 98.511  1.00 70.43  ? 103 GLY A H      1 
ATOM   524  H HA2    . GLY A 1 112 ? 111.086 141.866 100.918 1.00 70.43  ? 103 GLY A HA2    1 
ATOM   525  H HA3    . GLY A 1 112 ? 112.116 142.997 100.553 1.00 70.43  ? 103 GLY A HA3    1 
ATOM   526  N N      . SER A 1 113 ? 109.891 144.010 101.635 1.00 72.23  ? 104 SER A N      1 
ATOM   527  C CA     . SER A 1 113 ? 108.850 144.995 101.900 1.00 72.23  ? 104 SER A CA     1 
ATOM   528  C C      . SER A 1 113 ? 109.238 146.359 101.340 1.00 72.23  ? 104 SER A C      1 
ATOM   529  O O      . SER A 1 113 ? 109.019 147.387 101.980 1.00 72.23  ? 104 SER A O      1 
ATOM   530  C CB     . SER A 1 113 ? 108.582 145.102 103.403 1.00 72.23  ? 104 SER A CB     1 
ATOM   531  O OG     . SER A 1 113 ? 109.737 145.537 104.098 1.00 72.23  ? 104 SER A OG     1 
ATOM   532  H H      . SER A 1 113 ? 110.287 143.719 102.340 1.00 72.23  ? 104 SER A H      1 
ATOM   533  H HA     . SER A 1 113 ? 108.029 144.714 101.468 1.00 72.23  ? 104 SER A HA     1 
ATOM   534  H HB2    . SER A 1 113 ? 107.867 145.740 103.551 1.00 72.23  ? 104 SER A HB2    1 
ATOM   535  H HB3    . SER A 1 113 ? 108.322 144.230 103.739 1.00 72.23  ? 104 SER A HB3    1 
ATOM   536  H HG     . SER A 1 113 ? 109.953 146.309 103.846 1.00 72.23  ? 104 SER A HG     1 
ATOM   537  N N      . ASP A 1 117 ? 105.474 144.543 104.999 1.00 73.18  ? 108 ASP A N      1 
ATOM   538  C CA     . ASP A 1 117 ? 106.004 145.092 106.241 1.00 73.18  ? 108 ASP A CA     1 
ATOM   539  C C      . ASP A 1 117 ? 106.031 144.012 107.317 1.00 73.18  ? 108 ASP A C      1 
ATOM   540  O O      . ASP A 1 117 ? 105.384 142.975 107.178 1.00 73.18  ? 108 ASP A O      1 
ATOM   541  C CB     . ASP A 1 117 ? 105.165 146.286 106.697 1.00 73.18  ? 108 ASP A CB     1 
ATOM   542  C CG     . ASP A 1 117 ? 105.847 147.097 107.779 1.00 73.18  ? 108 ASP A CG     1 
ATOM   543  O OD1    . ASP A 1 117 ? 106.929 146.680 108.243 1.00 73.18  ? 108 ASP A OD1    1 
ATOM   544  O OD2    . ASP A 1 117 ? 105.302 148.154 108.162 1.00 73.18  ? 108 ASP A OD2    1 
ATOM   545  H H      . ASP A 1 117 ? 105.302 143.701 105.035 1.00 73.18  ? 108 ASP A H      1 
ATOM   546  H HA     . ASP A 1 117 ? 106.912 145.397 106.092 1.00 73.18  ? 108 ASP A HA     1 
ATOM   547  H HB2    . ASP A 1 117 ? 105.007 146.870 105.939 1.00 73.18  ? 108 ASP A HB2    1 
ATOM   548  H HB3    . ASP A 1 117 ? 104.321 145.964 107.050 1.00 73.18  ? 108 ASP A HB3    1 
ATOM   549  N N      . LYS A 1 118 ? 106.784 144.258 108.390 1.00 68.63  ? 109 LYS A N      1 
ATOM   550  C CA     . LYS A 1 118 ? 106.988 143.258 109.437 1.00 68.63  ? 109 LYS A CA     1 
ATOM   551  C C      . LYS A 1 118 ? 107.473 141.952 108.820 1.00 68.63  ? 109 LYS A C      1 
ATOM   552  O O      . LYS A 1 118 ? 107.061 140.858 109.210 1.00 68.63  ? 109 LYS A O      1 
ATOM   553  C CB     . LYS A 1 118 ? 105.713 143.044 110.252 1.00 68.63  ? 109 LYS A CB     1 
ATOM   554  C CG     . LYS A 1 118 ? 105.951 142.386 111.598 1.00 68.63  ? 109 LYS A CG     1 
ATOM   555  C CD     . LYS A 1 118 ? 104.709 142.430 112.471 1.00 68.63  ? 109 LYS A CD     1 
ATOM   556  C CE     . LYS A 1 118 ? 103.625 141.504 111.950 1.00 68.63  ? 109 LYS A CE     1 
ATOM   557  N NZ     . LYS A 1 118 ? 102.424 141.496 112.831 1.00 68.63  ? 109 LYS A NZ     1 
ATOM   558  H H      . LYS A 1 118 ? 107.190 145.001 108.536 1.00 68.63  ? 109 LYS A H      1 
ATOM   559  H HA     . LYS A 1 118 ? 107.677 143.576 110.042 1.00 68.63  ? 109 LYS A HA     1 
ATOM   560  H HB2    . LYS A 1 118 ? 105.296 143.905 110.411 1.00 68.63  ? 109 LYS A HB2    1 
ATOM   561  H HB3    . LYS A 1 118 ? 105.112 142.476 109.746 1.00 68.63  ? 109 LYS A HB3    1 
ATOM   562  H HG2    . LYS A 1 118 ? 106.193 141.457 111.462 1.00 68.63  ? 109 LYS A HG2    1 
ATOM   563  H HG3    . LYS A 1 118 ? 106.662 142.855 112.061 1.00 68.63  ? 109 LYS A HG3    1 
ATOM   564  H HD2    . LYS A 1 118 ? 104.940 142.152 113.371 1.00 68.63  ? 109 LYS A HD2    1 
ATOM   565  H HD3    . LYS A 1 118 ? 104.356 143.334 112.480 1.00 68.63  ? 109 LYS A HD3    1 
ATOM   566  H HE2    . LYS A 1 118 ? 103.350 141.798 111.068 1.00 68.63  ? 109 LYS A HE2    1 
ATOM   567  H HE3    . LYS A 1 118 ? 103.974 140.600 111.908 1.00 68.63  ? 109 LYS A HE3    1 
ATOM   568  H HZ1    . LYS A 1 118 ? 101.839 140.892 112.540 1.00 68.63  ? 109 LYS A HZ1    1 
ATOM   569  H HZ2    . LYS A 1 118 ? 102.660 141.291 113.665 1.00 68.63  ? 109 LYS A HZ2    1 
ATOM   570  H HZ3    . LYS A 1 118 ? 102.040 142.298 112.829 1.00 68.63  ? 109 LYS A HZ3    1 
ATOM   571  N N      . MET A 1 119 ? 108.374 142.080 107.845 1.00 69.21  ? 110 MET A N      1 
ATOM   572  C CA     . MET A 1 119 ? 108.739 140.947 107.004 1.00 69.21  ? 110 MET A CA     1 
ATOM   573  C C      . MET A 1 119 ? 109.380 139.829 107.815 1.00 69.21  ? 110 MET A C      1 
ATOM   574  O O      . MET A 1 119 ? 109.102 138.647 107.582 1.00 69.21  ? 110 MET A O      1 
ATOM   575  C CB     . MET A 1 119 ? 109.685 141.417 105.900 1.00 69.21  ? 110 MET A CB     1 
ATOM   576  C CG     . MET A 1 119 ? 109.832 140.452 104.739 1.00 69.21  ? 110 MET A CG     1 
ATOM   577  S SD     . MET A 1 119 ? 108.334 140.318 103.751 1.00 69.21  ? 110 MET A SD     1 
ATOM   578  C CE     . MET A 1 119 ? 108.968 139.459 102.316 1.00 69.21  ? 110 MET A CE     1 
ATOM   579  H H      . MET A 1 119 ? 108.784 142.811 107.653 1.00 69.21  ? 110 MET A H      1 
ATOM   580  H HA     . MET A 1 119 ? 107.937 140.603 106.581 1.00 69.21  ? 110 MET A HA     1 
ATOM   581  H HB2    . MET A 1 119 ? 109.352 142.256 105.544 1.00 69.21  ? 110 MET A HB2    1 
ATOM   582  H HB3    . MET A 1 119 ? 110.565 141.553 106.284 1.00 69.21  ? 110 MET A HB3    1 
ATOM   583  H HG2    . MET A 1 119 ? 110.545 140.764 104.160 1.00 69.21  ? 110 MET A HG2    1 
ATOM   584  H HG3    . MET A 1 119 ? 110.045 139.571 105.084 1.00 69.21  ? 110 MET A HG3    1 
ATOM   585  H HE1    . MET A 1 119 ? 109.579 140.044 101.843 1.00 69.21  ? 110 MET A HE1    1 
ATOM   586  H HE2    . MET A 1 119 ? 108.226 139.217 101.740 1.00 69.21  ? 110 MET A HE2    1 
ATOM   587  H HE3    . MET A 1 119 ? 109.434 138.661 102.610 1.00 69.21  ? 110 MET A HE3    1 
ATOM   588  N N      . VAL A 1 120 ? 110.242 140.177 108.773 1.00 63.94  ? 111 VAL A N      1 
ATOM   589  C CA     . VAL A 1 120 ? 110.992 139.158 109.496 1.00 63.94  ? 111 VAL A CA     1 
ATOM   590  C C      . VAL A 1 120 ? 110.073 138.203 110.234 1.00 63.94  ? 111 VAL A C      1 
ATOM   591  O O      . VAL A 1 120 ? 110.462 137.064 110.511 1.00 63.94  ? 111 VAL A O      1 
ATOM   592  C CB     . VAL A 1 120 ? 111.986 139.810 110.474 1.00 63.94  ? 111 VAL A CB     1 
ATOM   593  C CG1    . VAL A 1 120 ? 112.784 138.738 111.198 1.00 63.94  ? 111 VAL A CG1    1 
ATOM   594  C CG2    . VAL A 1 120 ? 112.909 140.762 109.734 1.00 63.94  ? 111 VAL A CG2    1 
ATOM   595  H H      . VAL A 1 120 ? 110.402 140.985 109.019 1.00 63.94  ? 111 VAL A H      1 
ATOM   596  H HA     . VAL A 1 120 ? 111.505 138.639 108.856 1.00 63.94  ? 111 VAL A HA     1 
ATOM   597  H HB     . VAL A 1 120 ? 111.493 140.320 111.137 1.00 63.94  ? 111 VAL A HB     1 
ATOM   598  H HG11   . VAL A 1 120 ? 112.222 138.320 111.869 1.00 63.94  ? 111 VAL A HG11   1 
ATOM   599  H HG12   . VAL A 1 120 ? 113.551 139.152 111.624 1.00 63.94  ? 111 VAL A HG12   1 
ATOM   600  H HG13   . VAL A 1 120 ? 113.081 138.077 110.554 1.00 63.94  ? 111 VAL A HG13   1 
ATOM   601  H HG21   . VAL A 1 120 ? 113.594 141.076 110.344 1.00 63.94  ? 111 VAL A HG21   1 
ATOM   602  H HG22   . VAL A 1 120 ? 113.318 140.290 108.992 1.00 63.94  ? 111 VAL A HG22   1 
ATOM   603  H HG23   . VAL A 1 120 ? 112.392 141.513 109.403 1.00 63.94  ? 111 VAL A HG23   1 
ATOM   604  N N      . PHE A 1 121 ? 108.861 138.639 110.577 1.00 64.08  ? 112 PHE A N      1 
ATOM   605  C CA     . PHE A 1 121 ? 107.924 137.740 111.240 1.00 64.08  ? 112 PHE A CA     1 
ATOM   606  C C      . PHE A 1 121 ? 107.398 136.679 110.280 1.00 64.08  ? 112 PHE A C      1 
ATOM   607  O O      . PHE A 1 121 ? 107.326 135.497 110.634 1.00 64.08  ? 112 PHE A O      1 
ATOM   608  C CB     . PHE A 1 121 ? 106.768 138.535 111.840 1.00 64.08  ? 112 PHE A CB     1 
ATOM   609  C CG     . PHE A 1 121 ? 105.614 137.682 112.270 1.00 64.08  ? 112 PHE A CG     1 
ATOM   610  C CD1    . PHE A 1 121 ? 105.779 136.716 113.243 1.00 64.08  ? 112 PHE A CD1    1 
ATOM   611  C CD2    . PHE A 1 121 ? 104.366 137.845 111.702 1.00 64.08  ? 112 PHE A CD2    1 
ATOM   612  C CE1    . PHE A 1 121 ? 104.723 135.929 113.639 1.00 64.08  ? 112 PHE A CE1    1 
ATOM   613  C CE2    . PHE A 1 121 ? 103.307 137.061 112.096 1.00 64.08  ? 112 PHE A CE2    1 
ATOM   614  C CZ     . PHE A 1 121 ? 103.485 136.102 113.066 1.00 64.08  ? 112 PHE A CZ     1 
ATOM   615  H H      . PHE A 1 121 ? 108.563 139.434 110.440 1.00 64.08  ? 112 PHE A H      1 
ATOM   616  H HA     . PHE A 1 121 ? 108.383 137.286 111.964 1.00 64.08  ? 112 PHE A HA     1 
ATOM   617  H HB2    . PHE A 1 121 ? 107.089 139.017 112.618 1.00 64.08  ? 112 PHE A HB2    1 
ATOM   618  H HB3    . PHE A 1 121 ? 106.442 139.162 111.176 1.00 64.08  ? 112 PHE A HB3    1 
ATOM   619  H HD1    . PHE A 1 121 ? 106.614 136.595 113.634 1.00 64.08  ? 112 PHE A HD1    1 
ATOM   620  H HD2    . PHE A 1 121 ? 104.240 138.491 111.045 1.00 64.08  ? 112 PHE A HD2    1 
ATOM   621  H HE1    . PHE A 1 121 ? 104.845 135.282 114.296 1.00 64.08  ? 112 PHE A HE1    1 
ATOM   622  H HE2    . PHE A 1 121 ? 102.470 137.178 111.707 1.00 64.08  ? 112 PHE A HE2    1 
ATOM   623  H HZ     . PHE A 1 121 ? 102.770 135.571 113.333 1.00 64.08  ? 112 PHE A HZ     1 
ATOM   624  N N      . LYS A 1 122 ? 107.020 137.079 109.063 1.00 64.77  ? 113 LYS A N      1 
ATOM   625  C CA     . LYS A 1 122 ? 106.443 136.128 108.118 1.00 64.77  ? 113 LYS A CA     1 
ATOM   626  C C      . LYS A 1 122 ? 107.497 135.181 107.561 1.00 64.77  ? 113 LYS A C      1 
ATOM   627  O O      . LYS A 1 122 ? 107.266 133.970 107.470 1.00 64.77  ? 113 LYS A O      1 
ATOM   628  C CB     . LYS A 1 122 ? 105.756 136.875 106.975 1.00 64.77  ? 113 LYS A CB     1 
ATOM   629  C CG     . LYS A 1 122 ? 104.555 137.695 107.398 1.00 64.77  ? 113 LYS A CG     1 
ATOM   630  C CD     . LYS A 1 122 ? 103.996 138.490 106.232 1.00 64.77  ? 113 LYS A CD     1 
ATOM   631  C CE     . LYS A 1 122 ? 102.839 139.372 106.665 1.00 64.77  ? 113 LYS A CE     1 
ATOM   632  N NZ     . LYS A 1 122 ? 102.344 140.223 105.552 1.00 64.77  ? 113 LYS A NZ     1 
ATOM   633  H H      . LYS A 1 122 ? 107.087 137.884 108.767 1.00 64.77  ? 113 LYS A H      1 
ATOM   634  H HA     . LYS A 1 122 ? 105.773 135.596 108.574 1.00 64.77  ? 113 LYS A HA     1 
ATOM   635  H HB2    . LYS A 1 122 ? 106.398 137.480 106.571 1.00 64.77  ? 113 LYS A HB2    1 
ATOM   636  H HB3    . LYS A 1 122 ? 105.456 136.231 106.317 1.00 64.77  ? 113 LYS A HB3    1 
ATOM   637  H HG2    . LYS A 1 122 ? 103.860 137.102 107.724 1.00 64.77  ? 113 LYS A HG2    1 
ATOM   638  H HG3    . LYS A 1 122 ? 104.819 138.318 108.093 1.00 64.77  ? 113 LYS A HG3    1 
ATOM   639  H HD2    . LYS A 1 122 ? 104.692 139.060 105.869 1.00 64.77  ? 113 LYS A HD2    1 
ATOM   640  H HD3    . LYS A 1 122 ? 103.674 137.878 105.552 1.00 64.77  ? 113 LYS A HD3    1 
ATOM   641  H HE2    . LYS A 1 122 ? 102.107 138.811 106.966 1.00 64.77  ? 113 LYS A HE2    1 
ATOM   642  H HE3    . LYS A 1 122 ? 103.133 139.953 107.384 1.00 64.77  ? 113 LYS A HE3    1 
ATOM   643  H HZ1    . LYS A 1 122 ? 101.646 140.704 105.824 1.00 64.77  ? 113 LYS A HZ1    1 
ATOM   644  H HZ2    . LYS A 1 122 ? 102.987 140.775 105.281 1.00 64.77  ? 113 LYS A HZ2    1 
ATOM   645  H HZ3    . LYS A 1 122 ? 102.093 139.713 104.867 1.00 64.77  ? 113 LYS A HZ3    1 
ATOM   646  N N      . THR A 1 123 ? 108.662 135.713 107.189 1.00 64.88  ? 114 THR A N      1 
ATOM   647  C CA     . THR A 1 123 ? 109.628 134.923 106.434 1.00 64.88  ? 114 THR A CA     1 
ATOM   648  C C      . THR A 1 123 ? 110.080 133.694 107.214 1.00 64.88  ? 114 THR A C      1 
ATOM   649  O O      . THR A 1 123 ? 110.253 132.615 106.638 1.00 64.88  ? 114 THR A O      1 
ATOM   650  C CB     . THR A 1 123 ? 110.831 135.788 106.065 1.00 64.88  ? 114 THR A CB     1 
ATOM   651  O OG1    . THR A 1 123 ? 110.380 137.007 105.464 1.00 64.88  ? 114 THR A OG1    1 
ATOM   652  C CG2    . THR A 1 123 ? 111.733 135.055 105.090 1.00 64.88  ? 114 THR A CG2    1 
ATOM   653  H H      . THR A 1 123 ? 108.912 136.517 107.360 1.00 64.88  ? 114 THR A H      1 
ATOM   654  H HA     . THR A 1 123 ? 109.214 134.619 105.612 1.00 64.88  ? 114 THR A HA     1 
ATOM   655  H HB     . THR A 1 123 ? 111.342 135.990 106.864 1.00 64.88  ? 114 THR A HB     1 
ATOM   656  H HG1    . THR A 1 123 ? 109.941 136.840 104.768 1.00 64.88  ? 114 THR A HG1    1 
ATOM   657  H HG21   . THR A 1 123 ? 112.433 135.648 104.777 1.00 64.88  ? 114 THR A HG21   1 
ATOM   658  H HG22   . THR A 1 123 ? 112.140 134.289 105.524 1.00 64.88  ? 114 THR A HG22   1 
ATOM   659  H HG23   . THR A 1 123 ? 111.217 134.748 104.328 1.00 64.88  ? 114 THR A HG23   1 
ATOM   660  N N      . ALA A 1 124 ? 110.275 133.836 108.527 1.00 62.95  ? 115 ALA A N      1 
ATOM   661  C CA     . ALA A 1 124 ? 110.803 132.728 109.317 1.00 62.95  ? 115 ALA A CA     1 
ATOM   662  C C      . ALA A 1 124 ? 109.955 131.475 109.164 1.00 62.95  ? 115 ALA A C      1 
ATOM   663  O O      . ALA A 1 124 ? 110.477 130.355 109.251 1.00 62.95  ? 115 ALA A O      1 
ATOM   664  C CB     . ALA A 1 124 ? 110.889 133.131 110.787 1.00 62.95  ? 115 ALA A CB     1 
ATOM   665  H H      . ALA A 1 124 ? 110.111 134.551 108.976 1.00 62.95  ? 115 ALA A H      1 
ATOM   666  H HA     . ALA A 1 124 ? 111.700 132.523 109.010 1.00 62.95  ? 115 ALA A HA     1 
ATOM   667  H HB1    . ALA A 1 124 ? 111.479 133.896 110.870 1.00 62.95  ? 115 ALA A HB1    1 
ATOM   668  H HB2    . ALA A 1 124 ? 111.241 132.385 111.299 1.00 62.95  ? 115 ALA A HB2    1 
ATOM   669  H HB3    . ALA A 1 124 ? 110.001 133.360 111.104 1.00 62.95  ? 115 ALA A HB3    1 
ATOM   670  N N      . TRP A 1 125 ? 108.652 131.640 108.930 1.00 62.68  ? 116 TRP A N      1 
ATOM   671  C CA     . TRP A 1 125 ? 107.787 130.482 108.755 1.00 62.68  ? 116 TRP A CA     1 
ATOM   672  C C      . TRP A 1 125 ? 108.264 129.597 107.612 1.00 62.68  ? 116 TRP A C      1 
ATOM   673  O O      . TRP A 1 125 ? 108.047 128.383 107.643 1.00 62.68  ? 116 TRP A O      1 
ATOM   674  C CB     . TRP A 1 125 ? 106.346 130.931 108.510 1.00 62.68  ? 116 TRP A CB     1 
ATOM   675  C CG     . TRP A 1 125 ? 105.685 131.522 109.714 1.00 62.68  ? 116 TRP A CG     1 
ATOM   676  C CD1    . TRP A 1 125 ? 105.540 132.845 109.999 1.00 62.68  ? 116 TRP A CD1    1 
ATOM   677  C CD2    . TRP A 1 125 ? 105.077 130.810 110.795 1.00 62.68  ? 116 TRP A CD2    1 
ATOM   678  N NE1    . TRP A 1 125 ? 104.880 133.002 111.192 1.00 62.68  ? 116 TRP A NE1    1 
ATOM   679  C CE2    . TRP A 1 125 ? 104.585 131.767 111.701 1.00 62.68  ? 116 TRP A CE2    1 
ATOM   680  C CE3    . TRP A 1 125 ? 104.903 129.456 111.086 1.00 62.68  ? 116 TRP A CE3    1 
ATOM   681  C CZ2    . TRP A 1 125 ? 103.931 131.415 112.875 1.00 62.68  ? 116 TRP A CZ2    1 
ATOM   682  C CZ3    . TRP A 1 125 ? 104.252 129.108 112.253 1.00 62.68  ? 116 TRP A CZ3    1 
ATOM   683  C CH2    . TRP A 1 125 ? 103.775 130.083 113.133 1.00 62.68  ? 116 TRP A CH2    1 
ATOM   684  H H      . TRP A 1 125 ? 108.254 132.400 108.870 1.00 62.68  ? 116 TRP A H      1 
ATOM   685  H HA     . TRP A 1 125 ? 107.802 129.953 109.568 1.00 62.68  ? 116 TRP A HA     1 
ATOM   686  H HB2    . TRP A 1 125 ? 106.343 131.602 107.809 1.00 62.68  ? 116 TRP A HB2    1 
ATOM   687  H HB3    . TRP A 1 125 ? 105.823 130.163 108.231 1.00 62.68  ? 116 TRP A HB3    1 
ATOM   688  H HD1    . TRP A 1 125 ? 105.844 133.542 109.463 1.00 62.68  ? 116 TRP A HD1    1 
ATOM   689  H HE1    . TRP A 1 125 ? 104.684 133.755 111.559 1.00 62.68  ? 116 TRP A HE1    1 
ATOM   690  H HE3    . TRP A 1 125 ? 105.218 128.801 110.506 1.00 62.68  ? 116 TRP A HE3    1 
ATOM   691  H HZ2    . TRP A 1 125 ? 103.612 132.061 113.462 1.00 62.68  ? 116 TRP A HZ2    1 
ATOM   692  H HZ3    . TRP A 1 125 ? 104.130 128.208 112.457 1.00 62.68  ? 116 TRP A HZ3    1 
ATOM   693  H HH2    . TRP A 1 125 ? 103.340 129.818 113.912 1.00 62.68  ? 116 TRP A HH2    1 
ATOM   694  N N      . VAL A 1 126 ? 108.942 130.173 106.617 1.00 63.16  ? 117 VAL A N      1 
ATOM   695  C CA     . VAL A 1 126 ? 109.365 129.390 105.459 1.00 63.16  ? 117 VAL A CA     1 
ATOM   696  C C      . VAL A 1 126 ? 110.243 128.226 105.901 1.00 63.16  ? 117 VAL A C      1 
ATOM   697  O O      . VAL A 1 126 ? 110.054 127.084 105.468 1.00 63.16  ? 117 VAL A O      1 
ATOM   698  C CB     . VAL A 1 126 ? 110.091 130.285 104.439 1.00 63.16  ? 117 VAL A CB     1 
ATOM   699  C CG1    . VAL A 1 126 ? 110.597 129.456 103.276 1.00 63.16  ? 117 VAL A CG1    1 
ATOM   700  C CG2    . VAL A 1 126 ? 109.168 131.381 103.945 1.00 63.16  ? 117 VAL A CG2    1 
ATOM   701  H H      . VAL A 1 126 ? 109.167 131.003 106.589 1.00 63.16  ? 117 VAL A H      1 
ATOM   702  H HA     . VAL A 1 126 ? 108.580 129.022 105.025 1.00 63.16  ? 117 VAL A HA     1 
ATOM   703  H HB     . VAL A 1 126 ? 110.855 130.703 104.867 1.00 63.16  ? 117 VAL A HB     1 
ATOM   704  H HG11   . VAL A 1 126 ? 111.383 128.962 103.555 1.00 63.16  ? 117 VAL A HG11   1 
ATOM   705  H HG12   . VAL A 1 126 ? 110.823 130.049 102.543 1.00 63.16  ? 117 VAL A HG12   1 
ATOM   706  H HG13   . VAL A 1 126 ? 109.898 128.842 103.000 1.00 63.16  ? 117 VAL A HG13   1 
ATOM   707  H HG21   . VAL A 1 126 ? 109.637 131.914 103.284 1.00 63.16  ? 117 VAL A HG21   1 
ATOM   708  H HG22   . VAL A 1 126 ? 108.383 130.975 103.545 1.00 63.16  ? 117 VAL A HG22   1 
ATOM   709  H HG23   . VAL A 1 126 ? 108.906 131.938 104.694 1.00 63.16  ? 117 VAL A HG23   1 
ATOM   710  N N      . GLY A 1 127 ? 111.219 128.498 106.769 1.00 62.35  ? 118 GLY A N      1 
ATOM   711  C CA     . GLY A 1 127 ? 112.049 127.428 107.295 1.00 62.35  ? 118 GLY A CA     1 
ATOM   712  C C      . GLY A 1 127 ? 111.431 126.704 108.470 1.00 62.35  ? 118 GLY A C      1 
ATOM   713  O O      . GLY A 1 127 ? 111.666 125.503 108.654 1.00 62.35  ? 118 GLY A O      1 
ATOM   714  H H      . GLY A 1 127 ? 111.416 129.282 107.062 1.00 62.35  ? 118 GLY A H      1 
ATOM   715  H HA2    . GLY A 1 127 ? 112.220 126.779 106.594 1.00 62.35  ? 118 GLY A HA2    1 
ATOM   716  H HA3    . GLY A 1 127 ? 112.899 127.797 107.580 1.00 62.35  ? 118 GLY A HA3    1 
ATOM   717  N N      . SER A 1 128 ? 110.635 127.409 109.279 1.00 61.26  ? 119 SER A N      1 
ATOM   718  C CA     . SER A 1 128 ? 110.023 126.778 110.443 1.00 61.26  ? 119 SER A CA     1 
ATOM   719  C C      . SER A 1 128 ? 109.101 125.639 110.026 1.00 61.26  ? 119 SER A C      1 
ATOM   720  O O      . SER A 1 128 ? 109.158 124.539 110.589 1.00 61.26  ? 119 SER A O      1 
ATOM   721  C CB     . SER A 1 128 ? 109.258 127.822 111.251 1.00 61.26  ? 119 SER A CB     1 
ATOM   722  O OG     . SER A 1 128 ? 110.059 128.968 111.473 1.00 61.26  ? 119 SER A OG     1 
ATOM   723  H H      . SER A 1 128 ? 110.438 128.240 109.176 1.00 61.26  ? 119 SER A H      1 
ATOM   724  H HA     . SER A 1 128 ? 110.720 126.410 111.008 1.00 61.26  ? 119 SER A HA     1 
ATOM   725  H HB2    . SER A 1 128 ? 108.463 128.082 110.760 1.00 61.26  ? 119 SER A HB2    1 
ATOM   726  H HB3    . SER A 1 128 ? 109.009 127.439 112.107 1.00 61.26  ? 119 SER A HB3    1 
ATOM   727  H HG     . SER A 1 128 ? 110.751 128.756 111.898 1.00 61.26  ? 119 SER A HG     1 
ATOM   728  N N      . LEU A 1 129 ? 108.240 125.886 109.036 1.00 61.15  ? 120 LEU A N      1 
ATOM   729  C CA     . LEU A 1 129 ? 107.347 124.842 108.550 1.00 61.15  ? 120 LEU A CA     1 
ATOM   730  C C      . LEU A 1 129 ? 108.135 123.688 107.955 1.00 61.15  ? 120 LEU A C      1 
ATOM   731  O O      . LEU A 1 129 ? 107.806 122.517 108.180 1.00 61.15  ? 120 LEU A O      1 
ATOM   732  C CB     . LEU A 1 129 ? 106.387 125.418 107.513 1.00 61.15  ? 120 LEU A CB     1 
ATOM   733  C CG     . LEU A 1 129 ? 105.410 126.474 108.023 1.00 61.15  ? 120 LEU A CG     1 
ATOM   734  C CD1    . LEU A 1 129 ? 104.707 127.145 106.858 1.00 61.15  ? 120 LEU A CD1    1 
ATOM   735  C CD2    . LEU A 1 129 ? 104.401 125.851 108.968 1.00 61.15  ? 120 LEU A CD2    1 
ATOM   736  H H      . LEU A 1 129 ? 108.156 126.642 108.634 1.00 61.15  ? 120 LEU A H      1 
ATOM   737  H HA     . LEU A 1 129 ? 106.825 124.499 109.292 1.00 61.15  ? 120 LEU A HA     1 
ATOM   738  H HB2    . LEU A 1 129 ? 106.910 125.826 106.806 1.00 61.15  ? 120 LEU A HB2    1 
ATOM   739  H HB3    . LEU A 1 129 ? 105.862 124.690 107.146 1.00 61.15  ? 120 LEU A HB3    1 
ATOM   740  H HG     . LEU A 1 129 ? 105.901 127.153 108.511 1.00 61.15  ? 120 LEU A HG     1 
ATOM   741  H HD11   . LEU A 1 129 ? 105.368 127.593 106.307 1.00 61.15  ? 120 LEU A HD11   1 
ATOM   742  H HD12   . LEU A 1 129 ? 104.071 127.791 107.203 1.00 61.15  ? 120 LEU A HD12   1 
ATOM   743  H HD13   . LEU A 1 129 ? 104.244 126.470 106.338 1.00 61.15  ? 120 LEU A HD13   1 
ATOM   744  H HD21   . LEU A 1 129 ? 103.962 125.112 108.518 1.00 61.15  ? 120 LEU A HD21   1 
ATOM   745  H HD22   . LEU A 1 129 ? 103.746 126.522 109.218 1.00 61.15  ? 120 LEU A HD22   1 
ATOM   746  H HD23   . LEU A 1 129 ? 104.863 125.530 109.758 1.00 61.15  ? 120 LEU A HD23   1 
ATOM   747  N N      . SER A 1 130 ? 109.179 123.997 107.185 1.00 61.38  ? 121 SER A N      1 
ATOM   748  C CA     . SER A 1 130 ? 109.991 122.943 106.593 1.00 61.38  ? 121 SER A CA     1 
ATOM   749  C C      . SER A 1 130 ? 110.548 122.028 107.670 1.00 61.38  ? 121 SER A C      1 
ATOM   750  O O      . SER A 1 130 ? 110.507 120.799 107.543 1.00 61.38  ? 121 SER A O      1 
ATOM   751  C CB     . SER A 1 130 ? 111.129 123.553 105.777 1.00 61.38  ? 121 SER A CB     1 
ATOM   752  O OG     . SER A 1 130 ? 110.647 124.537 104.883 1.00 61.38  ? 121 SER A OG     1 
ATOM   753  H H      . SER A 1 130 ? 109.432 124.797 106.995 1.00 61.38  ? 121 SER A H      1 
ATOM   754  H HA     . SER A 1 130 ? 109.441 122.411 105.997 1.00 61.38  ? 121 SER A HA     1 
ATOM   755  H HB2    . SER A 1 130 ? 111.765 123.964 106.383 1.00 61.38  ? 121 SER A HB2    1 
ATOM   756  H HB3    . SER A 1 130 ? 111.564 122.851 105.268 1.00 61.38  ? 121 SER A HB3    1 
ATOM   757  H HG     . SER A 1 130 ? 110.305 125.173 105.310 1.00 61.38  ? 121 SER A HG     1 
ATOM   758  N N      . MET A 1 131 ? 111.068 122.612 108.749 1.00 60.87  ? 122 MET A N      1 
ATOM   759  C CA     . MET A 1 131 ? 111.695 121.793 109.779 1.00 60.87  ? 122 MET A CA     1 
ATOM   760  C C      . MET A 1 131 ? 110.663 121.057 110.626 1.00 60.87  ? 122 MET A C      1 
ATOM   761  O O      . MET A 1 131 ? 110.927 119.942 111.085 1.00 60.87  ? 122 MET A O      1 
ATOM   762  C CB     . MET A 1 131 ? 112.593 122.658 110.662 1.00 60.87  ? 122 MET A CB     1 
ATOM   763  C CG     . MET A 1 131 ? 113.569 121.862 111.517 1.00 60.87  ? 122 MET A CG     1 
ATOM   764  S SD     . MET A 1 131 ? 114.689 120.837 110.542 1.00 60.87  ? 122 MET A SD     1 
ATOM   765  C CE     . MET A 1 131 ? 115.563 119.952 111.829 1.00 60.87  ? 122 MET A CE     1 
ATOM   766  H H      . MET A 1 131 ? 111.071 123.458 108.904 1.00 60.87  ? 122 MET A H      1 
ATOM   767  H HA     . MET A 1 131 ? 112.254 121.134 109.341 1.00 60.87  ? 122 MET A HA     1 
ATOM   768  H HB2    . MET A 1 131 ? 113.112 123.250 110.095 1.00 60.87  ? 122 MET A HB2    1 
ATOM   769  H HB3    . MET A 1 131 ? 112.035 123.181 111.259 1.00 60.87  ? 122 MET A HB3    1 
ATOM   770  H HG2    . MET A 1 131 ? 114.107 122.480 112.037 1.00 60.87  ? 122 MET A HG2    1 
ATOM   771  H HG3    . MET A 1 131 ? 113.068 121.279 112.110 1.00 60.87  ? 122 MET A HG3    1 
ATOM   772  H HE1    . MET A 1 131 ? 116.116 120.577 112.322 1.00 60.87  ? 122 MET A HE1    1 
ATOM   773  H HE2    . MET A 1 131 ? 116.118 119.270 111.421 1.00 60.87  ? 122 MET A HE2    1 
ATOM   774  H HE3    . MET A 1 131 ? 114.916 119.540 112.424 1.00 60.87  ? 122 MET A HE3    1 
ATOM   775  N N      . GLY A 1 132 ? 109.491 121.654 110.847 1.00 61.02  ? 123 GLY A N      1 
ATOM   776  C CA     . GLY A 1 132 ? 108.490 120.996 111.671 1.00 61.02  ? 123 GLY A CA     1 
ATOM   777  C C      . GLY A 1 132 ? 107.776 119.864 110.955 1.00 61.02  ? 123 GLY A C      1 
ATOM   778  O O      . GLY A 1 132 ? 107.434 118.846 111.569 1.00 61.02  ? 123 GLY A O      1 
ATOM   779  H H      . GLY A 1 132 ? 109.259 122.422 110.537 1.00 61.02  ? 123 GLY A H      1 
ATOM   780  H HA2    . GLY A 1 132 ? 108.914 120.635 112.466 1.00 61.02  ? 123 GLY A HA2    1 
ATOM   781  H HA3    . GLY A 1 132 ? 107.827 121.646 111.948 1.00 61.02  ? 123 GLY A HA3    1 
ATOM   782  N N      . MET A 1 133 ? 107.540 120.022 109.651 1.00 59.29  ? 124 MET A N      1 
ATOM   783  C CA     . MET A 1 133 ? 106.735 119.046 108.929 1.00 59.29  ? 124 MET A CA     1 
ATOM   784  C C      . MET A 1 133 ? 107.425 117.691 108.852 1.00 59.29  ? 124 MET A C      1 
ATOM   785  O O      . MET A 1 133 ? 106.752 116.656 108.855 1.00 59.29  ? 124 MET A O      1 
ATOM   786  C CB     . MET A 1 133 ? 106.422 119.564 107.527 1.00 59.29  ? 124 MET A CB     1 
ATOM   787  C CG     . MET A 1 133 ? 105.379 118.751 106.778 1.00 59.29  ? 124 MET A CG     1 
ATOM   788  S SD     . MET A 1 133 ? 103.747 118.818 107.540 1.00 59.29  ? 124 MET A SD     1 
ATOM   789  C CE     . MET A 1 133 ? 102.769 117.944 106.321 1.00 59.29  ? 124 MET A CE     1 
ATOM   790  H H      . MET A 1 133 ? 107.831 120.674 109.172 1.00 59.29  ? 124 MET A H      1 
ATOM   791  H HA     . MET A 1 133 ? 105.892 118.936 109.397 1.00 59.29  ? 124 MET A HA     1 
ATOM   792  H HB2    . MET A 1 133 ? 106.092 120.474 107.599 1.00 59.29  ? 124 MET A HB2    1 
ATOM   793  H HB3    . MET A 1 133 ? 107.238 119.553 107.004 1.00 59.29  ? 124 MET A HB3    1 
ATOM   794  H HG2    . MET A 1 133 ? 105.301 119.096 105.876 1.00 59.29  ? 124 MET A HG2    1 
ATOM   795  H HG3    . MET A 1 133 ? 105.660 117.823 106.754 1.00 59.29  ? 124 MET A HG3    1 
ATOM   796  H HE1    . MET A 1 133 ? 102.294 118.590 105.775 1.00 59.29  ? 124 MET A HE1    1 
ATOM   797  H HE2    . MET A 1 133 ? 102.135 117.368 106.778 1.00 59.29  ? 124 MET A HE2    1 
ATOM   798  H HE3    . MET A 1 133 ? 103.358 117.411 105.765 1.00 59.29  ? 124 MET A HE3    1 
ATOM   799  N N      . ILE A 1 134 ? 108.757 117.668 108.782 1.00 59.53  ? 125 ILE A N      1 
ATOM   800  C CA     . ILE A 1 134 ? 109.463 116.390 108.739 1.00 59.53  ? 125 ILE A CA     1 
ATOM   801  C C      . ILE A 1 134 ? 109.151 115.577 109.988 1.00 59.53  ? 125 ILE A C      1 
ATOM   802  O O      . ILE A 1 134 ? 108.792 114.395 109.912 1.00 59.53  ? 125 ILE A O      1 
ATOM   803  C CB     . ILE A 1 134 ? 110.977 116.612 108.577 1.00 59.53  ? 125 ILE A CB     1 
ATOM   804  C CG1    . ILE A 1 134 ? 111.270 117.291 107.240 1.00 59.53  ? 125 ILE A CG1    1 
ATOM   805  C CG2    . ILE A 1 134 ? 111.718 115.286 108.679 1.00 59.53  ? 125 ILE A CG2    1 
ATOM   806  C CD1    . ILE A 1 134 ? 112.727 117.646 107.033 1.00 59.53  ? 125 ILE A CD1    1 
ATOM   807  H H      . ILE A 1 134 ? 109.264 118.362 108.759 1.00 59.53  ? 125 ILE A H      1 
ATOM   808  H HA     . ILE A 1 134 ? 109.152 115.887 107.971 1.00 59.53  ? 125 ILE A HA     1 
ATOM   809  H HB     . ILE A 1 134 ? 111.282 117.192 109.292 1.00 59.53  ? 125 ILE A HB     1 
ATOM   810  H HG12   . ILE A 1 134 ? 111.007 116.693 106.522 1.00 59.53  ? 125 ILE A HG12   1 
ATOM   811  H HG13   . ILE A 1 134 ? 110.758 118.113 107.188 1.00 59.53  ? 125 ILE A HG13   1 
ATOM   812  H HG21   . ILE A 1 134 ? 111.671 114.962 109.592 1.00 59.53  ? 125 ILE A HG21   1 
ATOM   813  H HG22   . ILE A 1 134 ? 112.646 115.414 108.432 1.00 59.53  ? 125 ILE A HG22   1 
ATOM   814  H HG23   . ILE A 1 134 ? 111.303 114.646 108.079 1.00 59.53  ? 125 ILE A HG23   1 
ATOM   815  H HD11   . ILE A 1 134 ? 112.797 118.264 106.290 1.00 59.53  ? 125 ILE A HD11   1 
ATOM   816  H HD12   . ILE A 1 134 ? 113.069 118.060 107.841 1.00 59.53  ? 125 ILE A HD12   1 
ATOM   817  H HD13   . ILE A 1 134 ? 113.228 116.838 106.838 1.00 59.53  ? 125 ILE A HD13   1 
ATOM   818  N N      . PHE A 1 135 ? 109.292 116.196 111.160 1.00 60.31  ? 126 PHE A N      1 
ATOM   819  C CA     . PHE A 1 135 ? 109.004 115.485 112.397 1.00 60.31  ? 126 PHE A CA     1 
ATOM   820  C C      . PHE A 1 135 ? 107.530 115.126 112.491 1.00 60.31  ? 126 PHE A C      1 
ATOM   821  O O      . PHE A 1 135 ? 107.181 114.033 112.949 1.00 60.31  ? 126 PHE A O      1 
ATOM   822  C CB     . PHE A 1 135 ? 109.434 116.322 113.599 1.00 60.31  ? 126 PHE A CB     1 
ATOM   823  C CG     . PHE A 1 135 ? 110.912 116.550 113.675 1.00 60.31  ? 126 PHE A CG     1 
ATOM   824  C CD1    . PHE A 1 135 ? 111.783 115.482 113.783 1.00 60.31  ? 126 PHE A CD1    1 
ATOM   825  C CD2    . PHE A 1 135 ? 111.432 117.829 113.643 1.00 60.31  ? 126 PHE A CD2    1 
ATOM   826  C CE1    . PHE A 1 135 ? 113.142 115.686 113.851 1.00 60.31  ? 126 PHE A CE1    1 
ATOM   827  C CE2    . PHE A 1 135 ? 112.791 118.038 113.711 1.00 60.31  ? 126 PHE A CE2    1 
ATOM   828  C CZ     . PHE A 1 135 ? 113.647 116.966 113.816 1.00 60.31  ? 126 PHE A CZ     1 
ATOM   829  H H      . PHE A 1 135 ? 109.547 117.011 111.262 1.00 60.31  ? 126 PHE A H      1 
ATOM   830  H HA     . PHE A 1 135 ? 109.513 114.659 112.410 1.00 60.31  ? 126 PHE A HA     1 
ATOM   831  H HB2    . PHE A 1 135 ? 109.003 117.190 113.547 1.00 60.31  ? 126 PHE A HB2    1 
ATOM   832  H HB3    . PHE A 1 135 ? 109.161 115.868 114.412 1.00 60.31  ? 126 PHE A HB3    1 
ATOM   833  H HD1    . PHE A 1 135 ? 111.446 114.615 113.805 1.00 60.31  ? 126 PHE A HD1    1 
ATOM   834  H HD2    . PHE A 1 135 ? 110.858 118.557 113.571 1.00 60.31  ? 126 PHE A HD2    1 
ATOM   835  H HE1    . PHE A 1 135 ? 113.718 114.960 113.922 1.00 60.31  ? 126 PHE A HE1    1 
ATOM   836  H HE2    . PHE A 1 135 ? 113.131 118.903 113.687 1.00 60.31  ? 126 PHE A HE2    1 
ATOM   837  H HZ     . PHE A 1 135 ? 114.565 117.105 113.863 1.00 60.31  ? 126 PHE A HZ     1 
ATOM   838  N N      . PHE A 1 136 ? 106.647 116.028 112.060 1.00 62.28  ? 127 PHE A N      1 
ATOM   839  C CA     . PHE A 1 136 ? 105.223 115.722 112.132 1.00 62.28  ? 127 PHE A CA     1 
ATOM   840  C C      . PHE A 1 136 ? 104.862 114.531 111.255 1.00 62.28  ? 127 PHE A C      1 
ATOM   841  O O      . PHE A 1 136 ? 103.971 113.752 111.607 1.00 62.28  ? 127 PHE A O      1 
ATOM   842  C CB     . PHE A 1 136 ? 104.397 116.941 111.725 1.00 62.28  ? 127 PHE A CB     1 
ATOM   843  C CG     . PHE A 1 136 ? 102.920 116.775 111.948 1.00 62.28  ? 127 PHE A CG     1 
ATOM   844  C CD1    . PHE A 1 136 ? 102.130 116.134 111.010 1.00 62.28  ? 127 PHE A CD1    1 
ATOM   845  C CD2    . PHE A 1 136 ? 102.322 117.266 113.094 1.00 62.28  ? 127 PHE A CD2    1 
ATOM   846  C CE1    . PHE A 1 136 ? 100.773 115.981 111.213 1.00 62.28  ? 127 PHE A CE1    1 
ATOM   847  C CE2    . PHE A 1 136 ? 100.966 117.117 113.301 1.00 62.28  ? 127 PHE A CE2    1 
ATOM   848  C CZ     . PHE A 1 136 ? 100.191 116.474 112.359 1.00 62.28  ? 127 PHE A CZ     1 
ATOM   849  H H      . PHE A 1 136 ? 106.841 116.799 111.732 1.00 62.28  ? 127 PHE A H      1 
ATOM   850  H HA     . PHE A 1 136 ? 104.995 115.498 113.048 1.00 62.28  ? 127 PHE A HA     1 
ATOM   851  H HB2    . PHE A 1 136 ? 104.692 117.706 112.243 1.00 62.28  ? 127 PHE A HB2    1 
ATOM   852  H HB3    . PHE A 1 136 ? 104.536 117.111 110.780 1.00 62.28  ? 127 PHE A HB3    1 
ATOM   853  H HD1    . PHE A 1 136 ? 102.519 115.799 110.234 1.00 62.28  ? 127 PHE A HD1    1 
ATOM   854  H HD2    . PHE A 1 136 ? 102.840 117.701 113.733 1.00 62.28  ? 127 PHE A HD2    1 
ATOM   855  H HE1    . PHE A 1 136 ? 100.253 115.547 110.576 1.00 62.28  ? 127 PHE A HE1    1 
ATOM   856  H HE2    . PHE A 1 136 ? 100.574 117.450 114.076 1.00 62.28  ? 127 PHE A HE2    1 
ATOM   857  H HZ     . PHE A 1 136 ? 99.277  116.373 112.498 1.00 62.28  ? 127 PHE A HZ     1 
ATOM   858  N N      . CYS A 1 137 ? 105.536 114.375 110.115 1.00 61.44  ? 128 CYS A N      1 
ATOM   859  C CA     . CYS A 1 137 ? 105.176 113.348 109.147 1.00 61.44  ? 128 CYS A CA     1 
ATOM   860  C C      . CYS A 1 137 ? 105.928 112.038 109.334 1.00 61.44  ? 128 CYS A C      1 
ATOM   861  O O      . CYS A 1 137 ? 105.483 111.010 108.813 1.00 61.44  ? 128 CYS A O      1 
ATOM   862  C CB     . CYS A 1 137 ? 105.427 113.860 107.725 1.00 61.44  ? 128 CYS A CB     1 
ATOM   863  S SG     . CYS A 1 137 ? 104.368 115.233 107.225 1.00 61.44  ? 128 CYS A SG     1 
ATOM   864  H H      . CYS A 1 137 ? 106.209 114.855 109.881 1.00 61.44  ? 128 CYS A H      1 
ATOM   865  H HA     . CYS A 1 137 ? 104.228 113.160 109.230 1.00 61.44  ? 128 CYS A HA     1 
ATOM   866  H HB2    . CYS A 1 137 ? 106.348 114.161 107.662 1.00 61.44  ? 128 CYS A HB2    1 
ATOM   867  H HB3    . CYS A 1 137 ? 105.278 113.131 107.102 1.00 61.44  ? 128 CYS A HB3    1 
ATOM   868  H HG     . CYS A 1 137 ? 104.519 116.138 107.998 1.00 61.44  ? 128 CYS A HG     1 
ATOM   869  N N      . CYS A 1 138 ? 107.055 112.041 110.043 1.00 60.65  ? 129 CYS A N      1 
ATOM   870  C CA     . CYS A 1 138 ? 107.811 110.802 110.217 1.00 60.65  ? 129 CYS A CA     1 
ATOM   871  C C      . CYS A 1 138 ? 106.982 109.676 110.822 1.00 60.65  ? 129 CYS A C      1 
ATOM   872  O O      . CYS A 1 138 ? 107.000 108.565 110.270 1.00 60.65  ? 129 CYS A O      1 
ATOM   873  C CB     . CYS A 1 138 ? 109.056 111.083 111.069 1.00 60.65  ? 129 CYS A CB     1 
ATOM   874  S SG     . CYS A 1 138 ? 110.150 109.663 111.283 1.00 60.65  ? 129 CYS A SG     1 
ATOM   875  H H      . CYS A 1 138 ? 107.399 112.731 110.424 1.00 60.65  ? 129 CYS A H      1 
ATOM   876  H HA     . CYS A 1 138 ? 108.116 110.504 109.346 1.00 60.65  ? 129 CYS A HA     1 
ATOM   877  H HB2    . CYS A 1 138 ? 109.570 111.787 110.644 1.00 60.65  ? 129 CYS A HB2    1 
ATOM   878  H HB3    . CYS A 1 138 ? 108.777 111.372 111.951 1.00 60.65  ? 129 CYS A HB3    1 
ATOM   879  H HG     . CYS A 1 138 ? 111.088 109.987 111.958 1.00 60.65  ? 129 CYS A HG     1 
ATOM   880  N N      . PRO A 1 139 ? 106.242 109.875 111.918 1.00 62.58  ? 130 PRO A N      1 
ATOM   881  C CA     . PRO A 1 139 ? 105.518 108.737 112.510 1.00 62.58  ? 130 PRO A CA     1 
ATOM   882  C C      . PRO A 1 139 ? 104.503 108.109 111.572 1.00 62.58  ? 130 PRO A C      1 
ATOM   883  O O      . PRO A 1 139 ? 104.346 106.882 111.569 1.00 62.58  ? 130 PRO A O      1 
ATOM   884  C CB     . PRO A 1 139 ? 104.838 109.352 113.742 1.00 62.58  ? 130 PRO A CB     1 
ATOM   885  C CG     . PRO A 1 139 ? 105.523 110.649 113.976 1.00 62.58  ? 130 PRO A CG     1 
ATOM   886  C CD     . PRO A 1 139 ? 105.970 111.127 112.639 1.00 62.58  ? 130 PRO A CD     1 
ATOM   887  H HA     . PRO A 1 139 ? 106.145 108.056 112.800 1.00 62.58  ? 130 PRO A HA     1 
ATOM   888  H HB2    . PRO A 1 139 ? 103.896 109.492 113.557 1.00 62.58  ? 130 PRO A HB2    1 
ATOM   889  H HB3    . PRO A 1 139 ? 104.952 108.763 114.504 1.00 62.58  ? 130 PRO A HB3    1 
ATOM   890  H HG2    . PRO A 1 139 ? 104.899 111.278 114.371 1.00 62.58  ? 130 PRO A HG2    1 
ATOM   891  H HG3    . PRO A 1 139 ? 106.285 110.512 114.560 1.00 62.58  ? 130 PRO A HG3    1 
ATOM   892  H HD2    . PRO A 1 139 ? 105.260 111.623 112.201 1.00 62.58  ? 130 PRO A HD2    1 
ATOM   893  H HD3    . PRO A 1 139 ? 106.776 111.658 112.723 1.00 62.58  ? 130 PRO A HD3    1 
ATOM   894  N N      . ILE A 1 140 ? 103.803 108.915 110.769 1.00 61.54  ? 131 ILE A N      1 
ATOM   895  C CA     . ILE A 1 140 ? 102.771 108.364 109.901 1.00 61.54  ? 131 ILE A CA     1 
ATOM   896  C C      . ILE A 1 140 ? 103.379 107.535 108.780 1.00 61.54  ? 131 ILE A C      1 
ATOM   897  O O      . ILE A 1 140 ? 102.718 106.636 108.249 1.00 61.54  ? 131 ILE A O      1 
ATOM   898  C CB     . ILE A 1 140 ? 101.875 109.488 109.343 1.00 61.54  ? 131 ILE A CB     1 
ATOM   899  C CG1    . ILE A 1 140 ? 100.780 108.917 108.436 1.00 61.54  ? 131 ILE A CG1    1 
ATOM   900  C CG2    . ILE A 1 140 ? 102.694 110.513 108.584 1.00 61.54  ? 131 ILE A CG2    1 
ATOM   901  C CD1    . ILE A 1 140 ? 99.875  107.911 109.116 1.00 61.54  ? 131 ILE A CD1    1 
ATOM   902  H H      . ILE A 1 140 ? 103.908 109.767 110.713 1.00 61.54  ? 131 ILE A H      1 
ATOM   903  H HA     . ILE A 1 140 ? 102.213 107.774 110.431 1.00 61.54  ? 131 ILE A HA     1 
ATOM   904  H HB     . ILE A 1 140 ? 101.447 109.935 110.090 1.00 61.54  ? 131 ILE A HB     1 
ATOM   905  H HG12   . ILE A 1 140 ? 100.222 109.650 108.131 1.00 61.54  ? 131 ILE A HG12   1 
ATOM   906  H HG13   . ILE A 1 140 ? 101.190 108.484 107.673 1.00 61.54  ? 131 ILE A HG13   1 
ATOM   907  H HG21   . ILE A 1 140 ? 102.096 111.055 108.046 1.00 61.54  ? 131 ILE A HG21   1 
ATOM   908  H HG22   . ILE A 1 140 ? 103.159 111.076 109.223 1.00 61.54  ? 131 ILE A HG22   1 
ATOM   909  H HG23   . ILE A 1 140 ? 103.331 110.060 108.011 1.00 61.54  ? 131 ILE A HG23   1 
ATOM   910  H HD11   . ILE A 1 140 ? 99.115  107.732 108.540 1.00 61.54  ? 131 ILE A HD11   1 
ATOM   911  H HD12   . ILE A 1 140 ? 100.371 107.091 109.271 1.00 61.54  ? 131 ILE A HD12   1 
ATOM   912  H HD13   . ILE A 1 140 ? 99.570  108.280 109.960 1.00 61.54  ? 131 ILE A HD13   1 
ATOM   913  N N      . VAL A 1 141 ? 104.633 107.805 108.411 1.00 60.95  ? 132 VAL A N      1 
ATOM   914  C CA     . VAL A 1 141 ? 105.291 107.021 107.376 1.00 60.95  ? 132 VAL A CA     1 
ATOM   915  C C      . VAL A 1 141 ? 105.428 105.565 107.784 1.00 60.95  ? 132 VAL A C      1 
ATOM   916  O O      . VAL A 1 141 ? 105.594 104.692 106.924 1.00 60.95  ? 132 VAL A O      1 
ATOM   917  C CB     . VAL A 1 141 ? 106.674 107.615 107.058 1.00 60.95  ? 132 VAL A CB     1 
ATOM   918  C CG1    . VAL A 1 141 ? 107.360 106.787 105.991 1.00 60.95  ? 132 VAL A CG1    1 
ATOM   919  C CG2    . VAL A 1 141 ? 106.546 109.071 106.627 1.00 60.95  ? 132 VAL A CG2    1 
ATOM   920  H H      . VAL A 1 141 ? 105.118 108.432 108.744 1.00 60.95  ? 132 VAL A H      1 
ATOM   921  H HA     . VAL A 1 141 ? 104.757 107.055 106.567 1.00 60.95  ? 132 VAL A HA     1 
ATOM   922  H HB     . VAL A 1 141 ? 107.218 107.587 107.859 1.00 60.95  ? 132 VAL A HB     1 
ATOM   923  H HG11   . VAL A 1 141 ? 108.009 107.338 105.527 1.00 60.95  ? 132 VAL A HG11   1 
ATOM   924  H HG12   . VAL A 1 141 ? 106.692 106.466 105.366 1.00 60.95  ? 132 VAL A HG12   1 
ATOM   925  H HG13   . VAL A 1 141 ? 107.809 106.038 106.414 1.00 60.95  ? 132 VAL A HG13   1 
ATOM   926  H HG21   . VAL A 1 141 ? 105.633 109.369 106.763 1.00 60.95  ? 132 VAL A HG21   1 
ATOM   927  H HG22   . VAL A 1 141 ? 107.152 109.610 107.159 1.00 60.95  ? 132 VAL A HG22   1 
ATOM   928  H HG23   . VAL A 1 141 ? 106.777 109.148 105.689 1.00 60.95  ? 132 VAL A HG23   1 
ATOM   929  N N      . SER A 1 142 ? 105.393 105.283 109.089 1.00 62.71  ? 133 SER A N      1 
ATOM   930  C CA     . SER A 1 142 ? 105.514 103.912 109.569 1.00 62.71  ? 133 SER A CA     1 
ATOM   931  C C      . SER A 1 142 ? 104.327 103.054 109.160 1.00 62.71  ? 133 SER A C      1 
ATOM   932  O O      . SER A 1 142 ? 104.410 101.824 109.242 1.00 62.71  ? 133 SER A O      1 
ATOM   933  C CB     . SER A 1 142 ? 105.663 103.900 111.091 1.00 62.71  ? 133 SER A CB     1 
ATOM   934  O OG     . SER A 1 142 ? 106.829 104.596 111.494 1.00 62.71  ? 133 SER A OG     1 
ATOM   935  H H      . SER A 1 142 ? 105.299 105.867 109.713 1.00 62.71  ? 133 SER A H      1 
ATOM   936  H HA     . SER A 1 142 ? 106.314 103.517 109.188 1.00 62.71  ? 133 SER A HA     1 
ATOM   937  H HB2    . SER A 1 142 ? 104.888 104.330 111.486 1.00 62.71  ? 133 SER A HB2    1 
ATOM   938  H HB3    . SER A 1 142 ? 105.723 102.981 111.395 1.00 62.71  ? 133 SER A HB3    1 
ATOM   939  H HG     . SER A 1 142 ? 107.510 104.234 111.160 1.00 62.71  ? 133 SER A HG     1 
ATOM   940  N N      . VAL A 1 143 ? 103.229 103.669 108.734 1.00 63.27  ? 134 VAL A N      1 
ATOM   941  C CA     . VAL A 1 143 ? 102.109 102.918 108.179 1.00 63.27  ? 134 VAL A CA     1 
ATOM   942  C C      . VAL A 1 143 ? 102.238 102.783 106.669 1.00 63.27  ? 134 VAL A C      1 
ATOM   943  O O      . VAL A 1 143 ? 102.000 101.709 106.112 1.00 63.27  ? 134 VAL A O      1 
ATOM   944  C CB     . VAL A 1 143 ? 100.780 103.591 108.576 1.00 63.27  ? 134 VAL A CB     1 
ATOM   945  C CG1    . VAL A 1 143 ? 99.604  102.838 107.981 1.00 63.27  ? 134 VAL A CG1    1 
ATOM   946  C CG2    . VAL A 1 143 ? 100.658 103.664 110.088 1.00 63.27  ? 134 VAL A CG2    1 
ATOM   947  H H      . VAL A 1 143 ? 103.107 104.519 108.754 1.00 63.27  ? 134 VAL A H      1 
ATOM   948  H HA     . VAL A 1 143 ? 102.110 102.024 108.557 1.00 63.27  ? 134 VAL A HA     1 
ATOM   949  H HB     . VAL A 1 143 ? 100.766 104.496 108.228 1.00 63.27  ? 134 VAL A HB     1 
ATOM   950  H HG11   . VAL A 1 143 ? 98.786  103.154 108.397 1.00 63.27  ? 134 VAL A HG11   1 
ATOM   951  H HG12   . VAL A 1 143 ? 99.571  103.001 107.025 1.00 63.27  ? 134 VAL A HG12   1 
ATOM   952  H HG13   . VAL A 1 143 ? 99.716  101.890 108.153 1.00 63.27  ? 134 VAL A HG13   1 
ATOM   953  H HG21   . VAL A 1 143 ? 99.787  104.022 110.317 1.00 63.27  ? 134 VAL A HG21   1 
ATOM   954  H HG22   . VAL A 1 143 ? 100.756 102.771 110.455 1.00 63.27  ? 134 VAL A HG22   1 
ATOM   955  H HG23   . VAL A 1 143 ? 101.355 104.243 110.434 1.00 63.27  ? 134 VAL A HG23   1 
ATOM   956  N N      . PHE A 1 144 ? 102.630 103.860 105.986 1.00 62.64  ? 135 PHE A N      1 
ATOM   957  C CA     . PHE A 1 144 ? 102.780 103.798 104.538 1.00 62.64  ? 135 PHE A CA     1 
ATOM   958  C C      . PHE A 1 144 ? 103.827 102.769 104.137 1.00 62.64  ? 135 PHE A C      1 
ATOM   959  O O      . PHE A 1 144 ? 103.564 101.891 103.308 1.00 62.64  ? 135 PHE A O      1 
ATOM   960  C CB     . PHE A 1 144 ? 103.151 105.175 103.992 1.00 62.64  ? 135 PHE A CB     1 
ATOM   961  C CG     . PHE A 1 144 ? 101.974 106.085 103.786 1.00 62.64  ? 135 PHE A CG     1 
ATOM   962  C CD1    . PHE A 1 144 ? 101.251 106.563 104.865 1.00 62.64  ? 135 PHE A CD1    1 
ATOM   963  C CD2    . PHE A 1 144 ? 101.600 106.476 102.511 1.00 62.64  ? 135 PHE A CD2    1 
ATOM   964  C CE1    . PHE A 1 144 ? 100.171 107.407 104.677 1.00 62.64  ? 135 PHE A CE1    1 
ATOM   965  C CE2    . PHE A 1 144 ? 100.522 107.319 102.317 1.00 62.64  ? 135 PHE A CE2    1 
ATOM   966  C CZ     . PHE A 1 144 ? 99.807  107.785 103.402 1.00 62.64  ? 135 PHE A CZ     1 
ATOM   967  H H      . PHE A 1 144 ? 102.812 104.625 106.334 1.00 62.64  ? 135 PHE A H      1 
ATOM   968  H HA     . PHE A 1 144 ? 101.934 103.535 104.143 1.00 62.64  ? 135 PHE A HA     1 
ATOM   969  H HB2    . PHE A 1 144 ? 103.754 105.608 104.616 1.00 62.64  ? 135 PHE A HB2    1 
ATOM   970  H HB3    . PHE A 1 144 ? 103.591 105.063 103.135 1.00 62.64  ? 135 PHE A HB3    1 
ATOM   971  H HD1    . PHE A 1 144 ? 101.493 106.311 105.727 1.00 62.64  ? 135 PHE A HD1    1 
ATOM   972  H HD2    . PHE A 1 144 ? 102.078 106.165 101.776 1.00 62.64  ? 135 PHE A HD2    1 
ATOM   973  H HE1    . PHE A 1 144 ? 99.691  107.719 105.410 1.00 62.64  ? 135 PHE A HE1    1 
ATOM   974  H HE2    . PHE A 1 144 ? 100.278 107.572 101.456 1.00 62.64  ? 135 PHE A HE2    1 
ATOM   975  H HZ     . PHE A 1 144 ? 99.081  108.352 103.273 1.00 62.64  ? 135 PHE A HZ     1 
ATOM   976  N N      . THR A 1 145 ? 105.024 102.852 104.723 1.00 61.53  ? 136 THR A N      1 
ATOM   977  C CA     . THR A 1 145 ? 106.105 101.961 104.309 1.00 61.53  ? 136 THR A CA     1 
ATOM   978  C C      . THR A 1 145 ? 105.731 100.505 104.541 1.00 61.53  ? 136 THR A C      1 
ATOM   979  O O      . THR A 1 145 ? 105.940 99.651  103.673 1.00 61.53  ? 136 THR A O      1 
ATOM   980  C CB     . THR A 1 145 ? 107.390 102.305 105.058 1.00 61.53  ? 136 THR A CB     1 
ATOM   981  O OG1    . THR A 1 145 ? 107.168 102.202 106.469 1.00 61.53  ? 136 THR A OG1    1 
ATOM   982  C CG2    . THR A 1 145 ? 107.843 103.709 104.719 1.00 61.53  ? 136 THR A CG2    1 
ATOM   983  H H      . THR A 1 145 ? 105.230 103.404 105.350 1.00 61.53  ? 136 THR A H      1 
ATOM   984  H HA     . THR A 1 145 ? 106.269 102.082 103.360 1.00 61.53  ? 136 THR A HA     1 
ATOM   985  H HB     . THR A 1 145 ? 108.091 101.686 104.798 1.00 61.53  ? 136 THR A HB     1 
ATOM   986  H HG1    . THR A 1 145 ? 107.038 101.401 106.683 1.00 61.53  ? 136 THR A HG1    1 
ATOM   987  H HG21   . THR A 1 145 ? 108.062 103.768 103.776 1.00 61.53  ? 136 THR A HG21   1 
ATOM   988  H HG22   . THR A 1 145 ? 108.627 103.939 105.239 1.00 61.53  ? 136 THR A HG22   1 
ATOM   989  H HG23   . THR A 1 145 ? 107.135 104.339 104.918 1.00 61.53  ? 136 THR A HG23   1 
ATOM   990  N N      . ASP A 1 146 ? 105.172 100.204 105.714 1.00 64.86  ? 137 ASP A N      1 
ATOM   991  C CA     . ASP A 1 146 ? 104.730 98.843  105.992 1.00 64.86  ? 137 ASP A CA     1 
ATOM   992  C C      . ASP A 1 146 ? 103.590 98.432  105.071 1.00 64.86  ? 137 ASP A C      1 
ATOM   993  O O      . ASP A 1 146 ? 103.395 97.237  104.819 1.00 64.86  ? 137 ASP A O      1 
ATOM   994  C CB     . ASP A 1 146 ? 104.301 98.728  107.454 1.00 64.86  ? 137 ASP A CB     1 
ATOM   995  C CG     . ASP A 1 146 ? 103.903 97.319  107.837 1.00 64.86  ? 137 ASP A CG     1 
ATOM   996  O OD1    . ASP A 1 146 ? 104.161 96.387  107.048 1.00 64.86  ? 137 ASP A OD1    1 
ATOM   997  O OD2    . ASP A 1 146 ? 103.328 97.142  108.931 1.00 64.86  ? 137 ASP A OD2    1 
ATOM   998  H H      . ASP A 1 146 ? 105.041 100.761 106.355 1.00 64.86  ? 137 ASP A H      1 
ATOM   999  H HA     . ASP A 1 146 ? 105.470 98.233  105.846 1.00 64.86  ? 137 ASP A HA     1 
ATOM   1000 H HB2    . ASP A 1 146 ? 105.040 98.996  108.022 1.00 64.86  ? 137 ASP A HB2    1 
ATOM   1001 H HB3    . ASP A 1 146 ? 103.537 99.307  107.606 1.00 64.86  ? 137 ASP A HB3    1 
ATOM   1002 N N      . LEU A 1 147 ? 102.829 99.401  104.557 1.00 63.71  ? 138 LEU A N      1 
ATOM   1003 C CA     . LEU A 1 147 ? 101.699 99.083  103.692 1.00 63.71  ? 138 LEU A CA     1 
ATOM   1004 C C      . LEU A 1 147 ? 102.142 98.794  102.262 1.00 63.71  ? 138 LEU A C      1 
ATOM   1005 O O      . LEU A 1 147 ? 101.663 97.837  101.646 1.00 63.71  ? 138 LEU A O      1 
ATOM   1006 C CB     . LEU A 1 147 ? 100.693 100.234 103.716 1.00 63.71  ? 138 LEU A CB     1 
ATOM   1007 C CG     . LEU A 1 147 ? 99.496  100.111 102.774 1.00 63.71  ? 138 LEU A CG     1 
ATOM   1008 C CD1    . LEU A 1 147 ? 98.739  98.817  103.023 1.00 63.71  ? 138 LEU A CD1    1 
ATOM   1009 C CD2    . LEU A 1 147 ? 98.579  101.310 102.939 1.00 63.71  ? 138 LEU A CD2    1 
ATOM   1010 H H      . LEU A 1 147 ? 102.947 100.242 104.693 1.00 63.71  ? 138 LEU A H      1 
ATOM   1011 H HA     . LEU A 1 147 ? 101.256 98.290  104.034 1.00 63.71  ? 138 LEU A HA     1 
ATOM   1012 H HB2    . LEU A 1 147 ? 100.344 100.312 104.618 1.00 63.71  ? 138 LEU A HB2    1 
ATOM   1013 H HB3    . LEU A 1 147 ? 101.161 101.050 103.482 1.00 63.71  ? 138 LEU A HB3    1 
ATOM   1014 H HG     . LEU A 1 147 ? 99.812  100.102 101.858 1.00 63.71  ? 138 LEU A HG     1 
ATOM   1015 H HD11   . LEU A 1 147 ? 97.933  98.817  102.484 1.00 63.71  ? 138 LEU A HD11   1 
ATOM   1016 H HD12   . LEU A 1 147 ? 99.302  98.068  102.775 1.00 63.71  ? 138 LEU A HD12   1 
ATOM   1017 H HD13   . LEU A 1 147 ? 98.508  98.762  103.963 1.00 63.71  ? 138 LEU A HD13   1 
ATOM   1018 H HD21   . LEU A 1 147 ? 97.839  101.227 102.317 1.00 63.71  ? 138 LEU A HD21   1 
ATOM   1019 H HD22   . LEU A 1 147 ? 98.246  101.330 103.849 1.00 63.71  ? 138 LEU A HD22   1 
ATOM   1020 H HD23   . LEU A 1 147 ? 99.081  102.118 102.751 1.00 63.71  ? 138 LEU A HD23   1 
ATOM   1021 N N      . PHE A 1 148 ? 103.052 99.603  101.720 1.00 63.61  ? 139 PHE A N      1 
ATOM   1022 C CA     . PHE A 1 148 ? 103.475 99.465  100.333 1.00 63.61  ? 139 PHE A CA     1 
ATOM   1023 C C      . PHE A 1 148 ? 104.728 98.623  100.161 1.00 63.61  ? 139 PHE A C      1 
ATOM   1024 O O      . PHE A 1 148 ? 104.786 97.813  99.231  1.00 63.61  ? 139 PHE A O      1 
ATOM   1025 C CB     . PHE A 1 148 ? 103.724 100.844 99.715  1.00 63.61  ? 139 PHE A CB     1 
ATOM   1026 C CG     . PHE A 1 148 ? 102.470 101.563 99.293  1.00 63.61  ? 139 PHE A CG     1 
ATOM   1027 C CD1    . PHE A 1 148 ? 101.648 102.166 100.230 1.00 63.61  ? 139 PHE A CD1    1 
ATOM   1028 C CD2    . PHE A 1 148 ? 102.127 101.653 97.954  1.00 63.61  ? 139 PHE A CD2    1 
ATOM   1029 C CE1    . PHE A 1 148 ? 100.501 102.834 99.839  1.00 63.61  ? 139 PHE A CE1    1 
ATOM   1030 C CE2    . PHE A 1 148 ? 100.983 102.320 97.560  1.00 63.61  ? 139 PHE A CE2    1 
ATOM   1031 C CZ     . PHE A 1 148 ? 100.170 102.911 98.504  1.00 63.61  ? 139 PHE A CZ     1 
ATOM   1032 H H      . PHE A 1 148 ? 103.438 100.246 102.141 1.00 63.61  ? 139 PHE A H      1 
ATOM   1033 H HA     . PHE A 1 148 ? 102.763 99.040  99.830  1.00 63.61  ? 139 PHE A HA     1 
ATOM   1034 H HB2    . PHE A 1 148 ? 104.180 101.400 100.366 1.00 63.61  ? 139 PHE A HB2    1 
ATOM   1035 H HB3    . PHE A 1 148 ? 104.282 100.736 98.930  1.00 63.61  ? 139 PHE A HB3    1 
ATOM   1036 H HD1    . PHE A 1 148 ? 101.866 102.117 101.133 1.00 63.61  ? 139 PHE A HD1    1 
ATOM   1037 H HD2    . PHE A 1 148 ? 102.671 101.256 97.313  1.00 63.61  ? 139 PHE A HD2    1 
ATOM   1038 H HE1    . PHE A 1 148 ? 99.954  103.232 100.477 1.00 63.61  ? 139 PHE A HE1    1 
ATOM   1039 H HE2    . PHE A 1 148 ? 100.761 102.370 96.658  1.00 63.61  ? 139 PHE A HE2    1 
ATOM   1040 H HZ     . PHE A 1 148 ? 99.399  103.359 98.240  1.00 63.61  ? 139 PHE A HZ     1 
ATOM   1041 N N      . GLY A 1 149 ? 105.720 98.782  101.023 1.00 63.06  ? 140 GLY A N      1 
ATOM   1042 C CA     . GLY A 1 149 ? 106.979 98.085  100.884 1.00 63.06  ? 140 GLY A CA     1 
ATOM   1043 C C      . GLY A 1 149 ? 108.167 99.029  101.000 1.00 63.06  ? 140 GLY A C      1 
ATOM   1044 O O      . GLY A 1 149 ? 108.047 100.253 100.894 1.00 63.06  ? 140 GLY A O      1 
ATOM   1045 H H      . GLY A 1 149 ? 105.682 99.296  101.713 1.00 63.06  ? 140 GLY A H      1 
ATOM   1046 H HA2    . GLY A 1 149 ? 107.052 97.410  101.576 1.00 63.06  ? 140 GLY A HA2    1 
ATOM   1047 H HA3    . GLY A 1 149 ? 107.020 97.647  100.021 1.00 63.06  ? 140 GLY A HA3    1 
ATOM   1048 N N      . CYS A 1 150 ? 109.339 98.434  101.229 1.00 62.92  ? 141 CYS A N      1 
ATOM   1049 C CA     . CYS A 1 150 ? 110.542 99.230  101.453 1.00 62.92  ? 141 CYS A CA     1 
ATOM   1050 C C      . CYS A 1 150 ? 110.973 99.962  100.188 1.00 62.92  ? 141 CYS A C      1 
ATOM   1051 O O      . CYS A 1 150 ? 111.370 101.131 100.250 1.00 62.92  ? 141 CYS A O      1 
ATOM   1052 C CB     . CYS A 1 150 ? 111.671 98.336  101.962 1.00 62.92  ? 141 CYS A CB     1 
ATOM   1053 S SG     . CYS A 1 150 ? 111.382 97.616  103.591 1.00 62.92  ? 141 CYS A SG     1 
ATOM   1054 H H      . CYS A 1 150 ? 109.463 97.584  101.260 1.00 62.92  ? 141 CYS A H      1 
ATOM   1055 H HA     . CYS A 1 150 ? 110.358 99.895  102.134 1.00 62.92  ? 141 CYS A HA     1 
ATOM   1056 H HB2    . CYS A 1 150 ? 111.791 97.607  101.334 1.00 62.92  ? 141 CYS A HB2    1 
ATOM   1057 H HB3    . CYS A 1 150 ? 112.485 98.862  102.011 1.00 62.92  ? 141 CYS A HB3    1 
ATOM   1058 H HG     . CYS A 1 150 ? 111.238 98.503  104.386 1.00 62.92  ? 141 CYS A HG     1 
ATOM   1059 N N      . ARG A 1 151 ? 110.906 99.297  99.031  1.00 63.15  ? 142 ARG A N      1 
ATOM   1060 C CA     . ARG A 1 151 ? 111.406 99.914  97.807  1.00 63.15  ? 142 ARG A CA     1 
ATOM   1061 C C      . ARG A 1 151 ? 110.642 101.186 97.482  1.00 63.15  ? 142 ARG A C      1 
ATOM   1062 O O      . ARG A 1 151 ? 111.240 102.198 97.103  1.00 63.15  ? 142 ARG A O      1 
ATOM   1063 C CB     . ARG A 1 151 ? 111.318 98.935  96.636  1.00 63.15  ? 142 ARG A CB     1 
ATOM   1064 C CG     . ARG A 1 151 ? 111.787 99.536  95.318  1.00 63.15  ? 142 ARG A CG     1 
ATOM   1065 C CD     . ARG A 1 151 ? 111.894 98.499  94.212  1.00 63.15  ? 142 ARG A CD     1 
ATOM   1066 N NE     . ARG A 1 151 ? 110.604 97.905  93.876  1.00 63.15  ? 142 ARG A NE     1 
ATOM   1067 C CZ     . ARG A 1 151 ? 110.165 96.737  94.326  1.00 63.15  ? 142 ARG A CZ     1 
ATOM   1068 N NH1    . ARG A 1 151 ? 110.889 95.990  95.144  1.00 63.15  ? 142 ARG A NH1    1 
ATOM   1069 N NH2    . ARG A 1 151 ? 108.969 96.303  93.941  1.00 63.15  ? 142 ARG A NH2    1 
ATOM   1070 H H      . ARG A 1 151 ? 110.583 98.506  98.931  1.00 63.15  ? 142 ARG A H      1 
ATOM   1071 H HA     . ARG A 1 151 ? 112.340 100.148 97.929  1.00 63.15  ? 142 ARG A HA     1 
ATOM   1072 H HB2    . ARG A 1 151 ? 111.875 98.164  96.827  1.00 63.15  ? 142 ARG A HB2    1 
ATOM   1073 H HB3    . ARG A 1 151 ? 110.395 98.658  96.527  1.00 63.15  ? 142 ARG A HB3    1 
ATOM   1074 H HG2    . ARG A 1 151 ? 111.154 100.212 95.030  1.00 63.15  ? 142 ARG A HG2    1 
ATOM   1075 H HG3    . ARG A 1 151 ? 112.663 99.932  95.444  1.00 63.15  ? 142 ARG A HG3    1 
ATOM   1076 H HD2    . ARG A 1 151 ? 112.238 98.930  93.414  1.00 63.15  ? 142 ARG A HD2    1 
ATOM   1077 H HD3    . ARG A 1 151 ? 112.501 97.796  94.490  1.00 63.15  ? 142 ARG A HD3    1 
ATOM   1078 H HE     . ARG A 1 151 ? 110.125 98.309  93.287  1.00 63.15  ? 142 ARG A HE     1 
ATOM   1079 H HH11   . ARG A 1 151 ? 111.664 96.254  95.405  1.00 63.15  ? 142 ARG A HH11   1 
ATOM   1080 H HH12   . ARG A 1 151 ? 110.580 95.236  95.421  1.00 63.15  ? 142 ARG A HH12   1 
ATOM   1081 H HH21   . ARG A 1 151 ? 108.490 96.779  93.408  1.00 63.15  ? 142 ARG A HH21   1 
ATOM   1082 H HH22   . ARG A 1 151 ? 108.673 95.546  94.225  1.00 63.15  ? 142 ARG A HH22   1 
ATOM   1083 N N      . LYS A 1 152 ? 109.321 101.155 97.621  1.00 63.42  ? 143 LYS A N      1 
ATOM   1084 C CA     . LYS A 1 152 ? 108.525 102.345 97.379  1.00 63.42  ? 143 LYS A CA     1 
ATOM   1085 C C      . LYS A 1 152 ? 108.675 103.323 98.541  1.00 63.42  ? 143 LYS A C      1 
ATOM   1086 O O      . LYS A 1 152 ? 109.373 103.076 99.528  1.00 63.42  ? 143 LYS A O      1 
ATOM   1087 C CB     . LYS A 1 152 ? 107.056 101.981 97.166  1.00 63.42  ? 143 LYS A CB     1 
ATOM   1088 C CG     . LYS A 1 152 ? 106.681 101.694 95.719  1.00 63.42  ? 143 LYS A CG     1 
ATOM   1089 C CD     . LYS A 1 152 ? 106.717 100.208 95.408  1.00 63.42  ? 143 LYS A CD     1 
ATOM   1090 C CE     . LYS A 1 152 ? 105.510 99.489  95.990  1.00 63.42  ? 143 LYS A CE     1 
ATOM   1091 N NZ     . LYS A 1 152 ? 105.518 98.036  95.676  1.00 63.42  ? 143 LYS A NZ     1 
ATOM   1092 H H      . LYS A 1 152 ? 108.868 100.462 97.852  1.00 63.42  ? 143 LYS A H      1 
ATOM   1093 H HA     . LYS A 1 152 ? 108.850 102.784 96.577  1.00 63.42  ? 143 LYS A HA     1 
ATOM   1094 H HB2    . LYS A 1 152 ? 106.859 101.187 97.687  1.00 63.42  ? 143 LYS A HB2    1 
ATOM   1095 H HB3    . LYS A 1 152 ? 106.500 102.714 97.471  1.00 63.42  ? 143 LYS A HB3    1 
ATOM   1096 H HG2    . LYS A 1 152 ? 105.780 102.014 95.556  1.00 63.42  ? 143 LYS A HG2    1 
ATOM   1097 H HG3    . LYS A 1 152 ? 107.306 102.142 95.128  1.00 63.42  ? 143 LYS A HG3    1 
ATOM   1098 H HD2    . LYS A 1 152 ? 106.713 100.082 94.446  1.00 63.42  ? 143 LYS A HD2    1 
ATOM   1099 H HD3    . LYS A 1 152 ? 107.518 99.820  95.794  1.00 63.42  ? 143 LYS A HD3    1 
ATOM   1100 H HE2    . LYS A 1 152 ? 105.512 99.588  96.954  1.00 63.42  ? 143 LYS A HE2    1 
ATOM   1101 H HE3    . LYS A 1 152 ? 104.701 99.874  95.617  1.00 63.42  ? 143 LYS A HE3    1 
ATOM   1102 H HZ1    . LYS A 1 152 ? 104.806 97.644  96.037  1.00 63.42  ? 143 LYS A HZ1    1 
ATOM   1103 H HZ2    . LYS A 1 152 ? 105.500 97.915  94.795  1.00 63.42  ? 143 LYS A HZ2    1 
ATOM   1104 H HZ3    . LYS A 1 152 ? 106.254 97.658  96.005  1.00 63.42  ? 143 LYS A HZ3    1 
ATOM   1105 N N      . THR A 1 153 ? 108.017 104.463 98.387  1.00 61.36  ? 144 THR A N      1 
ATOM   1106 C CA     . THR A 1 153 ? 108.006 105.555 99.349  1.00 61.36  ? 144 THR A CA     1 
ATOM   1107 C C      . THR A 1 153 ? 109.317 106.330 99.355  1.00 61.36  ? 144 THR A C      1 
ATOM   1108 O O      . THR A 1 153 ? 109.299 107.541 99.579  1.00 61.36  ? 144 THR A O      1 
ATOM   1109 C CB     . THR A 1 153 ? 107.731 105.010 100.751 1.00 61.36  ? 144 THR A CB     1 
ATOM   1110 O OG1    . THR A 1 153 ? 106.678 104.042 100.685 1.00 61.36  ? 144 THR A OG1    1 
ATOM   1111 C CG2    . THR A 1 153 ? 107.324 106.125 101.693 1.00 61.36  ? 144 THR A CG2    1 
ATOM   1112 H H      . THR A 1 153 ? 107.541 104.635 97.692  1.00 61.36  ? 144 THR A H      1 
ATOM   1113 H HA     . THR A 1 153 ? 107.293 106.172 99.120  1.00 61.36  ? 144 THR A HA     1 
ATOM   1114 H HB     . THR A 1 153 ? 108.533 104.595 101.104 1.00 61.36  ? 144 THR A HB     1 
ATOM   1115 H HG1    . THR A 1 153 ? 105.974 104.403 100.404 1.00 61.36  ? 144 THR A HG1    1 
ATOM   1116 H HG21   . THR A 1 153 ? 107.866 106.914 101.539 1.00 61.36  ? 144 THR A HG21   1 
ATOM   1117 H HG22   . THR A 1 153 ? 106.392 106.348 101.548 1.00 61.36  ? 144 THR A HG22   1 
ATOM   1118 H HG23   . THR A 1 153 ? 107.436 105.838 102.613 1.00 61.36  ? 144 THR A HG23   1 
ATOM   1119 N N      . ALA A 1 154 ? 110.406 105.728 98.880  1.00 61.02  ? 145 ALA A N      1 
ATOM   1120 C CA     . ALA A 1 154 ? 111.649 106.475 98.735  1.00 61.02  ? 145 ALA A CA     1 
ATOM   1121 C C      . ALA A 1 154 ? 111.689 107.165 97.381  1.00 61.02  ? 145 ALA A C      1 
ATOM   1122 O O      . ALA A 1 154 ? 112.009 108.355 97.285  1.00 61.02  ? 145 ALA A O      1 
ATOM   1123 C CB     . ALA A 1 154 ? 112.855 105.547 98.899  1.00 61.02  ? 145 ALA A CB     1 
ATOM   1124 H H      . ALA A 1 154 ? 110.458 104.907 98.639  1.00 61.02  ? 145 ALA A H      1 
ATOM   1125 H HA     . ALA A 1 154 ? 111.696 107.156 99.423  1.00 61.02  ? 145 ALA A HA     1 
ATOM   1126 H HB1    . ALA A 1 154 ? 113.668 106.066 98.798  1.00 61.02  ? 145 ALA A HB1    1 
ATOM   1127 H HB2    . ALA A 1 154 ? 112.817 104.855 98.220  1.00 61.02  ? 145 ALA A HB2    1 
ATOM   1128 H HB3    . ALA A 1 154 ? 112.825 105.147 99.782  1.00 61.02  ? 145 ALA A HB3    1 
ATOM   1129 N N      . VAL A 1 155 ? 111.335 106.422 96.334  1.00 61.48  ? 146 VAL A N      1 
ATOM   1130 C CA     . VAL A 1 155 ? 111.115 107.028 95.031  1.00 61.48  ? 146 VAL A CA     1 
ATOM   1131 C C      . VAL A 1 155 ? 110.080 108.137 95.141  1.00 61.48  ? 146 VAL A C      1 
ATOM   1132 O O      . VAL A 1 155 ? 110.253 109.226 94.582  1.00 61.48  ? 146 VAL A O      1 
ATOM   1133 C CB     . VAL A 1 155 ? 110.688 105.950 94.019  1.00 61.48  ? 146 VAL A CB     1 
ATOM   1134 C CG1    . VAL A 1 155 ? 110.381 106.574 92.680  1.00 61.48  ? 146 VAL A CG1    1 
ATOM   1135 C CG2    . VAL A 1 155 ? 111.769 104.892 93.883  1.00 61.48  ? 146 VAL A CG2    1 
ATOM   1136 H H      . VAL A 1 155 ? 111.217 105.571 96.356  1.00 61.48  ? 146 VAL A H      1 
ATOM   1137 H HA     . VAL A 1 155 ? 111.946 107.421 94.719  1.00 61.48  ? 146 VAL A HA     1 
ATOM   1138 H HB     . VAL A 1 155 ? 109.882 105.516 94.340  1.00 61.48  ? 146 VAL A HB     1 
ATOM   1139 H HG11   . VAL A 1 155 ? 109.516 107.011 92.721  1.00 61.48  ? 146 VAL A HG11   1 
ATOM   1140 H HG12   . VAL A 1 155 ? 110.370 105.881 92.001  1.00 61.48  ? 146 VAL A HG12   1 
ATOM   1141 H HG13   . VAL A 1 155 ? 111.071 107.221 92.482  1.00 61.48  ? 146 VAL A HG13   1 
ATOM   1142 H HG21   . VAL A 1 155 ? 112.609 105.327 93.666  1.00 61.48  ? 146 VAL A HG21   1 
ATOM   1143 H HG22   . VAL A 1 155 ? 111.522 104.277 93.175  1.00 61.48  ? 146 VAL A HG22   1 
ATOM   1144 H HG23   . VAL A 1 155 ? 111.852 104.414 94.722  1.00 61.48  ? 146 VAL A HG23   1 
ATOM   1145 N N      . VAL A 1 156 ? 108.990 107.882 95.866  1.00 60.51  ? 147 VAL A N      1 
ATOM   1146 C CA     . VAL A 1 156 ? 107.931 108.878 95.978  1.00 60.51  ? 147 VAL A CA     1 
ATOM   1147 C C      . VAL A 1 156 ? 108.412 110.098 96.754  1.00 60.51  ? 147 VAL A C      1 
ATOM   1148 O O      . VAL A 1 156 ? 108.136 111.238 96.363  1.00 60.51  ? 147 VAL A O      1 
ATOM   1149 C CB     . VAL A 1 156 ? 106.676 108.259 96.616  1.00 60.51  ? 147 VAL A CB     1 
ATOM   1150 C CG1    . VAL A 1 156 ? 105.669 109.343 96.957  1.00 60.51  ? 147 VAL A CG1    1 
ATOM   1151 C CG2    . VAL A 1 156 ? 106.060 107.239 95.673  1.00 60.51  ? 147 VAL A CG2    1 
ATOM   1152 H H      . VAL A 1 156 ? 108.843 107.151 96.295  1.00 60.51  ? 147 VAL A H      1 
ATOM   1153 H HA     . VAL A 1 156 ? 107.690 109.175 95.087  1.00 60.51  ? 147 VAL A HA     1 
ATOM   1154 H HB     . VAL A 1 156 ? 106.924 107.805 97.437  1.00 60.51  ? 147 VAL A HB     1 
ATOM   1155 H HG11   . VAL A 1 156 ? 105.942 109.788 97.774  1.00 60.51  ? 147 VAL A HG11   1 
ATOM   1156 H HG12   . VAL A 1 156 ? 104.798 108.935 97.080  1.00 60.51  ? 147 VAL A HG12   1 
ATOM   1157 H HG13   . VAL A 1 156 ? 105.632 109.980 96.226  1.00 60.51  ? 147 VAL A HG13   1 
ATOM   1158 H HG21   . VAL A 1 156 ? 105.262 106.871 96.083  1.00 60.51  ? 147 VAL A HG21   1 
ATOM   1159 H HG22   . VAL A 1 156 ? 105.832 107.678 94.839  1.00 60.51  ? 147 VAL A HG22   1 
ATOM   1160 H HG23   . VAL A 1 156 ? 106.704 106.532 95.509  1.00 60.51  ? 147 VAL A HG23   1 
ATOM   1161 N N      . GLY A 1 157 ? 109.129 109.895 97.864  1.00 60.83  ? 148 GLY A N      1 
ATOM   1162 C CA     . GLY A 1 157 ? 109.661 111.035 98.588  1.00 60.83  ? 148 GLY A CA     1 
ATOM   1163 C C      . GLY A 1 157 ? 110.580 111.879 97.728  1.00 60.83  ? 148 GLY A C      1 
ATOM   1164 O O      . GLY A 1 157 ? 110.473 113.107 97.700  1.00 60.83  ? 148 GLY A O      1 
ATOM   1165 H H      . GLY A 1 157 ? 109.313 109.127 98.205  1.00 60.83  ? 148 GLY A H      1 
ATOM   1166 H HA2    . GLY A 1 157 ? 108.930 111.592 98.897  1.00 60.83  ? 148 GLY A HA2    1 
ATOM   1167 H HA3    . GLY A 1 157 ? 110.160 110.726 99.361  1.00 60.83  ? 148 GLY A HA3    1 
ATOM   1168 N N      . ALA A 1 158 ? 111.494 111.228 97.006  1.00 61.39  ? 149 ALA A N      1 
ATOM   1169 C CA     . ALA A 1 158 ? 112.424 111.971 96.164  1.00 61.39  ? 149 ALA A CA     1 
ATOM   1170 C C      . ALA A 1 158 ? 111.693 112.722 95.059  1.00 61.39  ? 149 ALA A C      1 
ATOM   1171 O O      . ALA A 1 158 ? 111.999 113.888 94.783  1.00 61.39  ? 149 ALA A O      1 
ATOM   1172 C CB     . ALA A 1 158 ? 113.462 111.022 95.568  1.00 61.39  ? 149 ALA A CB     1 
ATOM   1173 H H      . ALA A 1 158 ? 111.593 110.374 96.988  1.00 61.39  ? 149 ALA A H      1 
ATOM   1174 H HA     . ALA A 1 158 ? 112.892 112.622 96.710  1.00 61.39  ? 149 ALA A HA     1 
ATOM   1175 H HB1    . ALA A 1 158 ? 113.926 110.569 96.290  1.00 61.39  ? 149 ALA A HB1    1 
ATOM   1176 H HB2    . ALA A 1 158 ? 113.011 110.373 95.006  1.00 61.39  ? 149 ALA A HB2    1 
ATOM   1177 H HB3    . ALA A 1 158 ? 114.092 111.536 95.040  1.00 61.39  ? 149 ALA A HB3    1 
ATOM   1178 N N      . ALA A 1 159 ? 110.726 112.072 94.410  1.00 62.23  ? 150 ALA A N      1 
ATOM   1179 C CA     . ALA A 1 159 ? 109.994 112.733 93.337  1.00 62.23  ? 150 ALA A CA     1 
ATOM   1180 C C      . ALA A 1 159 ? 109.205 113.922 93.862  1.00 62.23  ? 150 ALA A C      1 
ATOM   1181 O O      . ALA A 1 159 ? 109.174 114.983 93.229  1.00 62.23  ? 150 ALA A O      1 
ATOM   1182 C CB     . ALA A 1 159 ? 109.066 111.736 92.645  1.00 62.23  ? 150 ALA A CB     1 
ATOM   1183 H H      . ALA A 1 159 ? 110.481 111.264 94.570  1.00 62.23  ? 150 ALA A H      1 
ATOM   1184 H HA     . ALA A 1 159 ? 110.627 113.060 92.678  1.00 62.23  ? 150 ALA A HA     1 
ATOM   1185 H HB1    . ALA A 1 159 ? 109.599 111.013 92.278  1.00 62.23  ? 150 ALA A HB1    1 
ATOM   1186 H HB2    . ALA A 1 159 ? 108.589 112.191 91.934  1.00 62.23  ? 150 ALA A HB2    1 
ATOM   1187 H HB3    . ALA A 1 159 ? 108.438 111.387 93.296  1.00 62.23  ? 150 ALA A HB3    1 
ATOM   1188 N N      . VAL A 1 160 ? 108.561 113.769 95.020  1.00 62.82  ? 151 VAL A N      1 
ATOM   1189 C CA     . VAL A 1 160 ? 107.786 114.870 95.581  1.00 62.82  ? 151 VAL A CA     1 
ATOM   1190 C C      . VAL A 1 160 ? 108.704 116.016 95.982  1.00 62.82  ? 151 VAL A C      1 
ATOM   1191 O O      . VAL A 1 160 ? 108.370 117.190 95.790  1.00 62.82  ? 151 VAL A O      1 
ATOM   1192 C CB     . VAL A 1 160 ? 106.941 114.377 96.768  1.00 62.82  ? 151 VAL A CB     1 
ATOM   1193 C CG1    . VAL A 1 160 ? 106.272 115.548 97.462  1.00 62.82  ? 151 VAL A CG1    1 
ATOM   1194 C CG2    . VAL A 1 160 ? 105.899 113.380 96.292  1.00 62.82  ? 151 VAL A CG2    1 
ATOM   1195 H H      . VAL A 1 160 ? 108.557 113.049 95.492  1.00 62.82  ? 151 VAL A H      1 
ATOM   1196 H HA     . VAL A 1 160 ? 107.178 115.201 94.902  1.00 62.82  ? 151 VAL A HA     1 
ATOM   1197 H HB     . VAL A 1 160 ? 107.517 113.932 97.409  1.00 62.82  ? 151 VAL A HB     1 
ATOM   1198 H HG11   . VAL A 1 160 ? 106.925 116.008 98.013  1.00 62.82  ? 151 VAL A HG11   1 
ATOM   1199 H HG12   . VAL A 1 160 ? 105.551 115.213 98.017  1.00 62.82  ? 151 VAL A HG12   1 
ATOM   1200 H HG13   . VAL A 1 160 ? 105.918 116.152 96.790  1.00 62.82  ? 151 VAL A HG13   1 
ATOM   1201 H HG21   . VAL A 1 160 ? 105.242 113.847 95.752  1.00 62.82  ? 151 VAL A HG21   1 
ATOM   1202 H HG22   . VAL A 1 160 ? 105.469 112.982 97.065  1.00 62.82  ? 151 VAL A HG22   1 
ATOM   1203 H HG23   . VAL A 1 160 ? 106.332 112.693 95.764  1.00 62.82  ? 151 VAL A HG23   1 
ATOM   1204 N N      . GLY A 1 161 ? 109.871 115.700 96.546  1.00 63.60  ? 152 GLY A N      1 
ATOM   1205 C CA     . GLY A 1 161 ? 110.822 116.749 96.878  1.00 63.60  ? 152 GLY A CA     1 
ATOM   1206 C C      . GLY A 1 161 ? 111.317 117.491 95.652  1.00 63.60  ? 152 GLY A C      1 
ATOM   1207 O O      . GLY A 1 161 ? 111.451 118.717 95.667  1.00 63.60  ? 152 GLY A O      1 
ATOM   1208 H H      . GLY A 1 161 ? 110.128 114.903 96.741  1.00 63.60  ? 152 GLY A H      1 
ATOM   1209 H HA2    . GLY A 1 161 ? 110.402 117.387 97.475  1.00 63.60  ? 152 GLY A HA2    1 
ATOM   1210 H HA3    . GLY A 1 161 ? 111.587 116.360 97.331  1.00 63.60  ? 152 GLY A HA3    1 
ATOM   1211 N N      . PHE A 1 162 ? 111.601 116.758 94.575  1.00 63.79  ? 153 PHE A N      1 
ATOM   1212 C CA     . PHE A 1 162 ? 112.006 117.396 93.327  1.00 63.79  ? 153 PHE A CA     1 
ATOM   1213 C C      . PHE A 1 162 ? 110.898 118.297 92.795  1.00 63.79  ? 153 PHE A C      1 
ATOM   1214 O O      . PHE A 1 162 ? 111.152 119.430 92.365  1.00 63.79  ? 153 PHE A O      1 
ATOM   1215 C CB     . PHE A 1 162 ? 112.380 116.327 92.300  1.00 63.79  ? 153 PHE A CB     1 
ATOM   1216 C CG     . PHE A 1 162 ? 112.488 116.844 90.897  1.00 63.79  ? 153 PHE A CG     1 
ATOM   1217 C CD1    . PHE A 1 162 ? 113.243 117.967 90.615  1.00 63.79  ? 153 PHE A CD1    1 
ATOM   1218 C CD2    . PHE A 1 162 ? 111.847 116.198 89.857  1.00 63.79  ? 153 PHE A CD2    1 
ATOM   1219 C CE1    . PHE A 1 162 ? 113.347 118.442 89.326  1.00 63.79  ? 153 PHE A CE1    1 
ATOM   1220 C CE2    . PHE A 1 162 ? 111.948 116.668 88.566  1.00 63.79  ? 153 PHE A CE2    1 
ATOM   1221 C CZ     . PHE A 1 162 ? 112.699 117.792 88.301  1.00 63.79  ? 153 PHE A CZ     1 
ATOM   1222 H H      . PHE A 1 162 ? 111.568 115.899 94.542  1.00 63.79  ? 153 PHE A H      1 
ATOM   1223 H HA     . PHE A 1 162 ? 112.788 117.945 93.490  1.00 63.79  ? 153 PHE A HA     1 
ATOM   1224 H HB2    . PHE A 1 162 ? 113.239 115.947 92.543  1.00 63.79  ? 153 PHE A HB2    1 
ATOM   1225 H HB3    . PHE A 1 162 ? 111.701 115.635 92.309  1.00 63.79  ? 153 PHE A HB3    1 
ATOM   1226 H HD1    . PHE A 1 162 ? 113.680 118.411 91.306  1.00 63.79  ? 153 PHE A HD1    1 
ATOM   1227 H HD2    . PHE A 1 162 ? 111.338 115.439 90.032  1.00 63.79  ? 153 PHE A HD2    1 
ATOM   1228 H HE1    . PHE A 1 162 ? 113.855 119.201 89.149  1.00 63.79  ? 153 PHE A HE1    1 
ATOM   1229 H HE2    . PHE A 1 162 ? 111.510 116.228 87.873  1.00 63.79  ? 153 PHE A HE2    1 
ATOM   1230 H HZ     . PHE A 1 162 ? 112.769 118.111 87.430  1.00 63.79  ? 153 PHE A HZ     1 
ATOM   1231 N N      . VAL A 1 163 ? 109.657 117.810 92.825  1.00 63.88  ? 154 VAL A N      1 
ATOM   1232 C CA     . VAL A 1 163 ? 108.533 118.613 92.356  1.00 63.88  ? 154 VAL A CA     1 
ATOM   1233 C C      . VAL A 1 163 ? 108.412 119.884 93.181  1.00 63.88  ? 154 VAL A C      1 
ATOM   1234 O O      . VAL A 1 163 ? 108.201 120.972 92.638  1.00 63.88  ? 154 VAL A O      1 
ATOM   1235 C CB     . VAL A 1 163 ? 107.231 117.792 92.394  1.00 63.88  ? 154 VAL A CB     1 
ATOM   1236 C CG1    . VAL A 1 163 ? 106.023 118.705 92.265  1.00 63.88  ? 154 VAL A CG1    1 
ATOM   1237 C CG2    . VAL A 1 163 ? 107.229 116.755 91.285  1.00 63.88  ? 154 VAL A CG2    1 
ATOM   1238 H H      . VAL A 1 163 ? 109.442 117.027 93.109  1.00 63.88  ? 154 VAL A H      1 
ATOM   1239 H HA     . VAL A 1 163 ? 108.695 118.871 91.435  1.00 63.88  ? 154 VAL A HA     1 
ATOM   1240 H HB     . VAL A 1 163 ? 107.172 117.328 93.243  1.00 63.88  ? 154 VAL A HB     1 
ATOM   1241 H HG11   . VAL A 1 163 ? 105.257 118.173 91.999  1.00 63.88  ? 154 VAL A HG11   1 
ATOM   1242 H HG12   . VAL A 1 163 ? 105.848 119.127 93.121  1.00 63.88  ? 154 VAL A HG12   1 
ATOM   1243 H HG13   . VAL A 1 163 ? 106.205 119.378 91.591  1.00 63.88  ? 154 VAL A HG13   1 
ATOM   1244 H HG21   . VAL A 1 163 ? 107.263 117.208 90.429  1.00 63.88  ? 154 VAL A HG21   1 
ATOM   1245 H HG22   . VAL A 1 163 ? 106.418 116.227 91.349  1.00 63.88  ? 154 VAL A HG22   1 
ATOM   1246 H HG23   . VAL A 1 163 ? 108.006 116.182 91.387  1.00 63.88  ? 154 VAL A HG23   1 
ATOM   1247 N N      . GLY A 1 164 ? 108.533 119.767 94.503  1.00 65.39  ? 155 GLY A N      1 
ATOM   1248 C CA     . GLY A 1 164 ? 108.416 120.941 95.352  1.00 65.39  ? 155 GLY A CA     1 
ATOM   1249 C C      . GLY A 1 164 ? 109.531 121.944 95.126  1.00 65.39  ? 155 GLY A C      1 
ATOM   1250 O O      . GLY A 1 164 ? 109.286 123.151 95.041  1.00 65.39  ? 155 GLY A O      1 
ATOM   1251 H H      . GLY A 1 164 ? 108.681 119.031 94.923  1.00 65.39  ? 155 GLY A H      1 
ATOM   1252 H HA2    . GLY A 1 164 ? 107.569 121.381 95.180  1.00 65.39  ? 155 GLY A HA2    1 
ATOM   1253 H HA3    . GLY A 1 164 ? 108.436 120.668 96.283  1.00 65.39  ? 155 GLY A HA3    1 
ATOM   1254 N N      . LEU A 1 165 ? 110.771 121.464 95.025  1.00 63.10  ? 156 LEU A N      1 
ATOM   1255 C CA     . LEU A 1 165 ? 111.884 122.374 94.789  1.00 63.10  ? 156 LEU A CA     1 
ATOM   1256 C C      . LEU A 1 165 ? 111.732 123.084 93.452  1.00 63.10  ? 156 LEU A C      1 
ATOM   1257 O O      . LEU A 1 165 ? 111.978 124.292 93.353  1.00 63.10  ? 156 LEU A O      1 
ATOM   1258 C CB     . LEU A 1 165 ? 113.210 121.619 94.850  1.00 63.10  ? 156 LEU A CB     1 
ATOM   1259 C CG     . LEU A 1 165 ? 113.700 121.223 96.244  1.00 63.10  ? 156 LEU A CG     1 
ATOM   1260 C CD1    . LEU A 1 165 ? 114.989 120.430 96.142  1.00 63.10  ? 156 LEU A CD1    1 
ATOM   1261 C CD2    . LEU A 1 165 ? 113.904 122.447 97.119  1.00 63.10  ? 156 LEU A CD2    1 
ATOM   1262 H H      . LEU A 1 165 ? 110.989 120.634 95.089  1.00 63.10  ? 156 LEU A H      1 
ATOM   1263 H HA     . LEU A 1 165 ? 111.886 123.052 95.482  1.00 63.10  ? 156 LEU A HA     1 
ATOM   1264 H HB2    . LEU A 1 165 ? 113.118 120.803 94.334  1.00 63.10  ? 156 LEU A HB2    1 
ATOM   1265 H HB3    . LEU A 1 165 ? 113.896 122.176 94.451  1.00 63.10  ? 156 LEU A HB3    1 
ATOM   1266 H HG     . LEU A 1 165 ? 113.033 120.660 96.663  1.00 63.10  ? 156 LEU A HG     1 
ATOM   1267 H HD11   . LEU A 1 165 ? 114.885 119.747 95.462  1.00 63.10  ? 156 LEU A HD11   1 
ATOM   1268 H HD12   . LEU A 1 165 ? 115.176 120.018 97.000  1.00 63.10  ? 156 LEU A HD12   1 
ATOM   1269 H HD13   . LEU A 1 165 ? 115.710 121.031 95.898  1.00 63.10  ? 156 LEU A HD13   1 
ATOM   1270 H HD21   . LEU A 1 165 ? 114.390 123.118 96.613  1.00 63.10  ? 156 LEU A HD21   1 
ATOM   1271 H HD22   . LEU A 1 165 ? 114.412 122.192 97.904  1.00 63.10  ? 156 LEU A HD22   1 
ATOM   1272 H HD23   . LEU A 1 165 ? 113.038 122.795 97.384  1.00 63.10  ? 156 LEU A HD23   1 
ATOM   1273 N N      . MET A 1 166 ? 111.327 122.358 92.408  1.00 65.00  ? 157 MET A N      1 
ATOM   1274 C CA     . MET A 1 166 ? 111.094 123.004 91.121  1.00 65.00  ? 157 MET A CA     1 
ATOM   1275 C C      . MET A 1 166 ? 109.964 124.022 91.220  1.00 65.00  ? 157 MET A C      1 
ATOM   1276 O O      . MET A 1 166 ? 110.108 125.170 90.784  1.00 65.00  ? 157 MET A O      1 
ATOM   1277 C CB     . MET A 1 166 ? 110.785 121.952 90.055  1.00 65.00  ? 157 MET A CB     1 
ATOM   1278 C CG     . MET A 1 166 ? 112.018 121.404 89.354  1.00 65.00  ? 157 MET A CG     1 
ATOM   1279 S SD     . MET A 1 166 ? 112.793 122.619 88.272  1.00 65.00  ? 157 MET A SD     1 
ATOM   1280 C CE     . MET A 1 166 ? 114.370 121.840 87.945  1.00 65.00  ? 157 MET A CE     1 
ATOM   1281 H H      . MET A 1 166 ? 111.183 121.510 92.420  1.00 65.00  ? 157 MET A H      1 
ATOM   1282 H HA     . MET A 1 166 ? 111.905 123.465 90.855  1.00 65.00  ? 157 MET A HA     1 
ATOM   1283 H HB2    . MET A 1 166 ? 110.326 121.207 90.473  1.00 65.00  ? 157 MET A HB2    1 
ATOM   1284 H HB3    . MET A 1 166 ? 110.214 122.351 89.379  1.00 65.00  ? 157 MET A HB3    1 
ATOM   1285 H HG2    . MET A 1 166 ? 112.669 121.133 90.020  1.00 65.00  ? 157 MET A HG2    1 
ATOM   1286 H HG3    . MET A 1 166 ? 111.758 120.643 88.811  1.00 65.00  ? 157 MET A HG3    1 
ATOM   1287 H HE1    . MET A 1 166 ? 114.758 122.237 87.149  1.00 65.00  ? 157 MET A HE1    1 
ATOM   1288 H HE2    . MET A 1 166 ? 114.952 121.987 88.705  1.00 65.00  ? 157 MET A HE2    1 
ATOM   1289 H HE3    . MET A 1 166 ? 114.232 120.890 87.807  1.00 65.00  ? 157 MET A HE3    1 
ATOM   1290 N N      . SER A 1 167 ? 108.835 123.626 91.810  1.00 65.57  ? 158 SER A N      1 
ATOM   1291 C CA     . SER A 1 167 ? 107.699 124.528 91.929  1.00 65.57  ? 158 SER A CA     1 
ATOM   1292 C C      . SER A 1 167 ? 108.045 125.769 92.732  1.00 65.57  ? 158 SER A C      1 
ATOM   1293 O O      . SER A 1 167 ? 107.412 126.813 92.542  1.00 65.57  ? 158 SER A O      1 
ATOM   1294 C CB     . SER A 1 167 ? 106.521 123.802 92.576  1.00 65.57  ? 158 SER A CB     1 
ATOM   1295 O OG     . SER A 1 167 ? 105.386 124.644 92.655  1.00 65.57  ? 158 SER A OG     1 
ATOM   1296 H H      . SER A 1 167 ? 108.705 122.845 92.146  1.00 65.57  ? 158 SER A H      1 
ATOM   1297 H HA     . SER A 1 167 ? 107.427 124.811 91.042  1.00 65.57  ? 158 SER A HA     1 
ATOM   1298 H HB2    . SER A 1 167 ? 106.299 123.024 92.040  1.00 65.57  ? 158 SER A HB2    1 
ATOM   1299 H HB3    . SER A 1 167 ? 106.773 123.527 93.472  1.00 65.57  ? 158 SER A HB3    1 
ATOM   1300 H HG     . SER A 1 167 ? 105.553 125.311 93.137  1.00 65.57  ? 158 SER A HG     1 
ATOM   1301 N N      . SER A 1 168 ? 109.031 125.682 93.625  1.00 65.22  ? 159 SER A N      1 
ATOM   1302 C CA     . SER A 1 168 ? 109.492 126.881 94.313  1.00 65.22  ? 159 SER A CA     1 
ATOM   1303 C C      . SER A 1 168 ? 109.953 127.935 93.318  1.00 65.22  ? 159 SER A C      1 
ATOM   1304 O O      . SER A 1 168 ? 109.902 129.134 93.614  1.00 65.22  ? 159 SER A O      1 
ATOM   1305 C CB     . SER A 1 168 ? 110.616 126.532 95.283  1.00 65.22  ? 159 SER A CB     1 
ATOM   1306 O OG     . SER A 1 168 ? 110.186 125.559 96.218  1.00 65.22  ? 159 SER A OG     1 
ATOM   1307 H H      . SER A 1 168 ? 109.441 124.958 93.844  1.00 65.22  ? 159 SER A H      1 
ATOM   1308 H HA     . SER A 1 168 ? 108.757 127.254 94.825  1.00 65.22  ? 159 SER A HA     1 
ATOM   1309 H HB2    . SER A 1 168 ? 111.369 126.181 94.783  1.00 65.22  ? 159 SER A HB2    1 
ATOM   1310 H HB3    . SER A 1 168 ? 110.882 127.333 95.760  1.00 65.22  ? 159 SER A HB3    1 
ATOM   1311 H HG     . SER A 1 168 ? 109.553 125.864 96.679  1.00 65.22  ? 159 SER A HG     1 
ATOM   1312 N N      . SER A 1 169 ? 110.406 127.511 92.142  1.00 65.94  ? 160 SER A N      1 
ATOM   1313 C CA     . SER A 1 169 ? 110.676 128.440 91.060  1.00 65.94  ? 160 SER A CA     1 
ATOM   1314 C C      . SER A 1 169 ? 109.365 128.948 90.465  1.00 65.94  ? 160 SER A C      1 
ATOM   1315 O O      . SER A 1 169 ? 108.294 128.371 90.665  1.00 65.94  ? 160 SER A O      1 
ATOM   1316 C CB     . SER A 1 169 ? 111.521 127.769 89.978  1.00 65.94  ? 160 SER A CB     1 
ATOM   1317 O OG     . SER A 1 169 ? 111.766 128.649 88.897  1.00 65.94  ? 160 SER A OG     1 
ATOM   1318 H H      . SER A 1 169 ? 110.563 126.688 91.947  1.00 65.94  ? 160 SER A H      1 
ATOM   1319 H HA     . SER A 1 169 ? 111.170 129.201 91.404  1.00 65.94  ? 160 SER A HA     1 
ATOM   1320 H HB2    . SER A 1 169 ? 112.370 127.499 90.362  1.00 65.94  ? 160 SER A HB2    1 
ATOM   1321 H HB3    . SER A 1 169 ? 111.048 126.992 89.642  1.00 65.94  ? 160 SER A HB3    1 
ATOM   1322 H HG     . SER A 1 169 ? 111.060 128.778 88.462  1.00 65.94  ? 160 SER A HG     1 
ATOM   1323 N N      . PHE A 1 170 ? 109.462 130.049 89.721  1.00 66.01  ? 161 PHE A N      1 
ATOM   1324 C CA     . PHE A 1 170 ? 108.300 130.661 89.079  1.00 66.01  ? 161 PHE A CA     1 
ATOM   1325 C C      . PHE A 1 170 ? 107.292 131.150 90.116  1.00 66.01  ? 161 PHE A C      1 
ATOM   1326 O O      . PHE A 1 170 ? 106.082 130.970 89.965  1.00 66.01  ? 161 PHE A O      1 
ATOM   1327 C CB     . PHE A 1 170 ? 107.637 129.690 88.101  1.00 66.01  ? 161 PHE A CB     1 
ATOM   1328 C CG     . PHE A 1 170 ? 108.610 128.901 87.279  1.00 66.01  ? 161 PHE A CG     1 
ATOM   1329 C CD1    . PHE A 1 170 ? 109.290 129.492 86.230  1.00 66.01  ? 161 PHE A CD1    1 
ATOM   1330 C CD2    . PHE A 1 170 ? 108.842 127.565 87.554  1.00 66.01  ? 161 PHE A CD2    1 
ATOM   1331 C CE1    . PHE A 1 170 ? 110.186 128.765 85.474  1.00 66.01  ? 161 PHE A CE1    1 
ATOM   1332 C CE2    . PHE A 1 170 ? 109.736 126.834 86.800  1.00 66.01  ? 161 PHE A CE2    1 
ATOM   1333 C CZ     . PHE A 1 170 ? 110.409 127.435 85.760  1.00 66.01  ? 161 PHE A CZ     1 
ATOM   1334 H H      . PHE A 1 170 ? 110.200 130.465 89.570  1.00 66.01  ? 161 PHE A H      1 
ATOM   1335 H HA     . PHE A 1 170 ? 108.596 131.432 88.572  1.00 66.01  ? 161 PHE A HA     1 
ATOM   1336 H HB2    . PHE A 1 170 ? 107.094 129.063 88.602  1.00 66.01  ? 161 PHE A HB2    1 
ATOM   1337 H HB3    . PHE A 1 170 ? 107.076 130.196 87.492  1.00 66.01  ? 161 PHE A HB3    1 
ATOM   1338 H HD1    . PHE A 1 170 ? 109.144 130.389 86.034  1.00 66.01  ? 161 PHE A HD1    1 
ATOM   1339 H HD2    . PHE A 1 170 ? 108.390 127.156 88.256  1.00 66.01  ? 161 PHE A HD2    1 
ATOM   1340 H HE1    . PHE A 1 170 ? 110.639 129.172 84.771  1.00 66.01  ? 161 PHE A HE1    1 
ATOM   1341 H HE2    . PHE A 1 170 ? 109.884 125.937 86.994  1.00 66.01  ? 161 PHE A HE2    1 
ATOM   1342 H HZ     . PHE A 1 170 ? 111.012 126.943 85.250  1.00 66.01  ? 161 PHE A HZ     1 
ATOM   1343 N N      . VAL A 1 171 ? 107.795 131.766 91.181  1.00 67.48  ? 162 VAL A N      1 
ATOM   1344 C CA     . VAL A 1 171 ? 106.969 132.320 92.249  1.00 67.48  ? 162 VAL A CA     1 
ATOM   1345 C C      . VAL A 1 171 ? 107.305 133.798 92.384  1.00 67.48  ? 162 VAL A C      1 
ATOM   1346 O O      . VAL A 1 171 ? 108.462 134.157 92.634  1.00 67.48  ? 162 VAL A O      1 
ATOM   1347 C CB     . VAL A 1 171 ? 107.188 131.581 93.576  1.00 67.48  ? 162 VAL A CB     1 
ATOM   1348 C CG1    . VAL A 1 171 ? 106.589 132.363 94.718  1.00 67.48  ? 162 VAL A CG1    1 
ATOM   1349 C CG2    . VAL A 1 171 ? 106.583 130.190 93.507  1.00 67.48  ? 162 VAL A CG2    1 
ATOM   1350 H H      . VAL A 1 171 ? 108.637 131.879 91.310  1.00 67.48  ? 162 VAL A H      1 
ATOM   1351 H HA     . VAL A 1 171 ? 106.032 132.243 92.007  1.00 67.48  ? 162 VAL A HA     1 
ATOM   1352 H HB     . VAL A 1 171 ? 108.140 131.489 93.738  1.00 67.48  ? 162 VAL A HB     1 
ATOM   1353 H HG11   . VAL A 1 171 ? 106.453 131.765 95.469  1.00 67.48  ? 162 VAL A HG11   1 
ATOM   1354 H HG12   . VAL A 1 171 ? 107.201 133.072 94.968  1.00 67.48  ? 162 VAL A HG12   1 
ATOM   1355 H HG13   . VAL A 1 171 ? 105.739 132.737 94.436  1.00 67.48  ? 162 VAL A HG13   1 
ATOM   1356 H HG21   . VAL A 1 171 ? 106.750 129.731 94.345  1.00 67.48  ? 162 VAL A HG21   1 
ATOM   1357 H HG22   . VAL A 1 171 ? 105.628 130.269 93.356  1.00 67.48  ? 162 VAL A HG22   1 
ATOM   1358 H HG23   . VAL A 1 171 ? 106.994 129.704 92.775  1.00 67.48  ? 162 VAL A HG23   1 
ATOM   1359 N N      . SER A 1 172 ? 106.296 134.652 92.228  1.00 70.83  ? 163 SER A N      1 
ATOM   1360 C CA     . SER A 1 172 ? 106.481 136.096 92.254  1.00 70.83  ? 163 SER A CA     1 
ATOM   1361 C C      . SER A 1 172 ? 106.119 136.725 93.594  1.00 70.83  ? 163 SER A C      1 
ATOM   1362 O O      . SER A 1 172 ? 106.131 137.955 93.707  1.00 70.83  ? 163 SER A O      1 
ATOM   1363 C CB     . SER A 1 172 ? 105.650 136.749 91.144  1.00 70.83  ? 163 SER A CB     1 
ATOM   1364 O OG     . SER A 1 172 ? 104.275 136.434 91.286  1.00 70.83  ? 163 SER A OG     1 
ATOM   1365 H H      . SER A 1 172 ? 105.480 134.412 92.104  1.00 70.83  ? 163 SER A H      1 
ATOM   1366 H HA     . SER A 1 172 ? 107.414 136.295 92.078  1.00 70.83  ? 163 SER A HA     1 
ATOM   1367 H HB2    . SER A 1 172 ? 105.759 137.712 91.193  1.00 70.83  ? 163 SER A HB2    1 
ATOM   1368 H HB3    . SER A 1 172 ? 105.961 136.423 90.285  1.00 70.83  ? 163 SER A HB3    1 
ATOM   1369 H HG     . SER A 1 172 ? 103.832 136.801 90.674  1.00 70.83  ? 163 SER A HG     1 
ATOM   1370 N N      . SER A 1 173 ? 105.797 135.922 94.605  1.00 69.16  ? 164 SER A N      1 
ATOM   1371 C CA     . SER A 1 173 ? 105.425 136.448 95.910  1.00 69.16  ? 164 SER A CA     1 
ATOM   1372 C C      . SER A 1 173 ? 105.877 135.469 96.981  1.00 69.16  ? 164 SER A C      1 
ATOM   1373 O O      . SER A 1 173 ? 106.165 134.304 96.703  1.00 69.16  ? 164 SER A O      1 
ATOM   1374 C CB     . SER A 1 173 ? 103.915 136.690 96.012  1.00 69.16  ? 164 SER A CB     1 
ATOM   1375 O OG     . SER A 1 173 ? 103.566 137.154 97.304  1.00 69.16  ? 164 SER A OG     1 
ATOM   1376 H H      . SER A 1 173 ? 105.788 135.064 94.559  1.00 69.16  ? 164 SER A H      1 
ATOM   1377 H HA     . SER A 1 173 ? 105.878 137.292 96.058  1.00 69.16  ? 164 SER A HA     1 
ATOM   1378 H HB2    . SER A 1 173 ? 103.658 137.357 95.357  1.00 69.16  ? 164 SER A HB2    1 
ATOM   1379 H HB3    . SER A 1 173 ? 103.449 135.858 95.839  1.00 69.16  ? 164 SER A HB3    1 
ATOM   1380 H HG     . SER A 1 173 ? 102.740 137.299 97.344  1.00 69.16  ? 164 SER A HG     1 
ATOM   1381 N N      . ILE A 1 174 ? 105.950 135.960 98.218  1.00 68.87  ? 165 ILE A N      1 
ATOM   1382 C CA     . ILE A 1 174 ? 106.371 135.093 99.312  1.00 68.87  ? 165 ILE A CA     1 
ATOM   1383 C C      . ILE A 1 174 ? 105.228 134.190 99.755  1.00 68.87  ? 165 ILE A C      1 
ATOM   1384 O O      . ILE A 1 174 ? 105.464 133.105 100.298 1.00 68.87  ? 165 ILE A O      1 
ATOM   1385 C CB     . ILE A 1 174 ? 106.911 135.931 100.483 1.00 68.87  ? 165 ILE A CB     1 
ATOM   1386 C CG1    . ILE A 1 174 ? 107.789 135.064 101.385 1.00 68.87  ? 165 ILE A CG1    1 
ATOM   1387 C CG2    . ILE A 1 174 ? 105.767 136.537 101.281 1.00 68.87  ? 165 ILE A CG2    1 
ATOM   1388 C CD1    . ILE A 1 174 ? 108.466 135.824 102.494 1.00 68.87  ? 165 ILE A CD1    1 
ATOM   1389 H H      . ILE A 1 174 ? 105.767 136.769 98.445  1.00 68.87  ? 165 ILE A H      1 
ATOM   1390 H HA     . ILE A 1 174 ? 107.090 134.524 98.998  1.00 68.87  ? 165 ILE A HA     1 
ATOM   1391 H HB     . ILE A 1 174 ? 107.449 136.654 100.126 1.00 68.87  ? 165 ILE A HB     1 
ATOM   1392 H HG12   . ILE A 1 174 ? 107.240 134.374 101.789 1.00 68.87  ? 165 ILE A HG12   1 
ATOM   1393 H HG13   . ILE A 1 174 ? 108.484 134.658 100.845 1.00 68.87  ? 165 ILE A HG13   1 
ATOM   1394 H HG21   . ILE A 1 174 ? 106.109 137.278 101.805 1.00 68.87  ? 165 ILE A HG21   1 
ATOM   1395 H HG22   . ILE A 1 174 ? 105.087 136.853 100.666 1.00 68.87  ? 165 ILE A HG22   1 
ATOM   1396 H HG23   . ILE A 1 174 ? 105.396 135.860 101.868 1.00 68.87  ? 165 ILE A HG23   1 
ATOM   1397 H HD11   . ILE A 1 174 ? 109.013 136.524 102.106 1.00 68.87  ? 165 ILE A HD11   1 
ATOM   1398 H HD12   . ILE A 1 174 ? 109.023 135.213 103.001 1.00 68.87  ? 165 ILE A HD12   1 
ATOM   1399 H HD13   . ILE A 1 174 ? 107.792 136.213 103.073 1.00 68.87  ? 165 ILE A HD13   1 
ATOM   1400 N N      . GLU A 1 175 ? 103.982 134.606 99.533  1.00 68.89  ? 166 GLU A N      1 
ATOM   1401 C CA     . GLU A 1 175 ? 102.839 133.842 100.031 1.00 68.89  ? 166 GLU A CA     1 
ATOM   1402 C C      . GLU A 1 175 ? 102.840 132.396 99.557  1.00 68.89  ? 166 GLU A C      1 
ATOM   1403 O O      . GLU A 1 175 ? 102.681 131.495 100.397 1.00 68.89  ? 166 GLU A O      1 
ATOM   1404 C CB     . GLU A 1 175 ? 101.536 134.545 99.623  1.00 68.89  ? 166 GLU A CB     1 
ATOM   1405 C CG     . GLU A 1 175 ? 101.370 135.941 100.202 1.00 68.89  ? 166 GLU A CG     1 
ATOM   1406 C CD     . GLU A 1 175 ? 101.142 135.931 101.699 1.00 68.89  ? 166 GLU A CD     1 
ATOM   1407 O OE1    . GLU A 1 175 ? 100.861 134.848 102.252 1.00 68.89  ? 166 GLU A OE1    1 
ATOM   1408 O OE2    . GLU A 1 175 ? 101.245 137.007 102.323 1.00 68.89  ? 166 GLU A OE2    1 
ATOM   1409 H H      . GLU A 1 175 ? 103.772 135.319 99.100  1.00 68.89  ? 166 GLU A H      1 
ATOM   1410 H HA     . GLU A 1 175 ? 102.874 133.830 101.000 1.00 68.89  ? 166 GLU A HA     1 
ATOM   1411 H HB2    . GLU A 1 175 ? 101.502 134.630 98.660  1.00 68.89  ? 166 GLU A HB2    1 
ATOM   1412 H HB3    . GLU A 1 175 ? 100.787 134.010 99.927  1.00 68.89  ? 166 GLU A HB3    1 
ATOM   1413 H HG2    . GLU A 1 175 ? 102.174 136.453 100.024 1.00 68.89  ? 166 GLU A HG2    1 
ATOM   1414 H HG3    . GLU A 1 175 ? 100.606 136.368 99.783  1.00 68.89  ? 166 GLU A HG3    1 
ATOM   1415 N N      . PRO A 1 176 ? 103.016 132.096 98.271  1.00 66.17  ? 167 PRO A N      1 
ATOM   1416 C CA     . PRO A 1 176 ? 102.998 130.689 97.850  1.00 66.17  ? 167 PRO A CA     1 
ATOM   1417 C C      . PRO A 1 176 ? 104.149 129.882 98.407  1.00 66.17  ? 167 PRO A C      1 
ATOM   1418 O O      . PRO A 1 176 ? 104.080 128.645 98.397  1.00 66.17  ? 167 PRO A O      1 
ATOM   1419 C CB     . PRO A 1 176 ? 103.063 130.775 96.318  1.00 66.17  ? 167 PRO A CB     1 
ATOM   1420 C CG     . PRO A 1 176 ? 102.747 132.200 95.983  1.00 66.17  ? 167 PRO A CG     1 
ATOM   1421 C CD     . PRO A 1 176 ? 103.244 132.998 97.133  1.00 66.17  ? 167 PRO A CD     1 
ATOM   1422 H HA     . PRO A 1 176 ? 102.164 130.271 98.113  1.00 66.17  ? 167 PRO A HA     1 
ATOM   1423 H HB2    . PRO A 1 176 ? 103.952 130.538 96.011  1.00 66.17  ? 167 PRO A HB2    1 
ATOM   1424 H HB3    . PRO A 1 176 ? 102.400 130.181 95.935  1.00 66.17  ? 167 PRO A HB3    1 
ATOM   1425 H HG2    . PRO A 1 176 ? 103.202 132.454 95.165  1.00 66.17  ? 167 PRO A HG2    1 
ATOM   1426 H HG3    . PRO A 1 176 ? 101.788 132.307 95.887  1.00 66.17  ? 167 PRO A HG3    1 
ATOM   1427 H HD2    . PRO A 1 176 ? 104.189 133.176 97.031  1.00 66.17  ? 167 PRO A HD2    1 
ATOM   1428 H HD3    . PRO A 1 176 ? 102.735 133.816 97.220  1.00 66.17  ? 167 PRO A HD3    1 
ATOM   1429 N N      . LEU A 1 177 ? 105.208 130.531 98.893  1.00 65.27  ? 168 LEU A N      1 
ATOM   1430 C CA     . LEU A 1 177 ? 106.374 129.776 99.328  1.00 65.27  ? 168 LEU A CA     1 
ATOM   1431 C C      . LEU A 1 177 ? 106.046 128.833 100.473 1.00 65.27  ? 168 LEU A C      1 
ATOM   1432 O O      . LEU A 1 177 ? 106.537 127.704 100.472 1.00 65.27  ? 168 LEU A O      1 
ATOM   1433 C CB     . LEU A 1 177 ? 107.513 130.718 99.724  1.00 65.27  ? 168 LEU A CB     1 
ATOM   1434 C CG     . LEU A 1 177 ? 108.341 131.308 98.578  1.00 65.27  ? 168 LEU A CG     1 
ATOM   1435 C CD1    . LEU A 1 177 ? 109.442 132.194 99.129  1.00 65.27  ? 168 LEU A CD1    1 
ATOM   1436 C CD2    . LEU A 1 177 ? 108.934 130.218 97.706  1.00 65.27  ? 168 LEU A CD2    1 
ATOM   1437 H H      . LEU A 1 177 ? 105.270 131.386 98.982  1.00 65.27  ? 168 LEU A H      1 
ATOM   1438 H HA     . LEU A 1 177 ? 106.683 129.230 98.593  1.00 65.27  ? 168 LEU A HA     1 
ATOM   1439 H HB2    . LEU A 1 177 ? 107.146 131.461 100.224 1.00 65.27  ? 168 LEU A HB2    1 
ATOM   1440 H HB3    . LEU A 1 177 ? 108.124 130.221 100.286 1.00 65.27  ? 168 LEU A HB3    1 
ATOM   1441 H HG     . LEU A 1 177 ? 107.765 131.855 98.021  1.00 65.27  ? 168 LEU A HG     1 
ATOM   1442 H HD11   . LEU A 1 177 ? 109.896 132.634 98.394  1.00 65.27  ? 168 LEU A HD11   1 
ATOM   1443 H HD12   . LEU A 1 177 ? 109.048 132.856 99.717  1.00 65.27  ? 168 LEU A HD12   1 
ATOM   1444 H HD13   . LEU A 1 177 ? 110.069 131.645 99.626  1.00 65.27  ? 168 LEU A HD13   1 
ATOM   1445 H HD21   . LEU A 1 177 ? 109.658 130.594 97.183  1.00 65.27  ? 168 LEU A HD21   1 
ATOM   1446 H HD22   . LEU A 1 177 ? 109.268 129.508 98.277  1.00 65.27  ? 168 LEU A HD22   1 
ATOM   1447 H HD23   . LEU A 1 177 ? 108.244 129.873 97.118  1.00 65.27  ? 168 LEU A HD23   1 
ATOM   1448 N N      . TYR A 1 178 ? 105.189 129.243 101.413 1.00 65.29  ? 169 TYR A N      1 
ATOM   1449 C CA     . TYR A 1 178 ? 104.830 128.353 102.513 1.00 65.29  ? 169 TYR A CA     1 
ATOM   1450 C C      . TYR A 1 178 ? 104.349 127.007 101.993 1.00 65.29  ? 169 TYR A C      1 
ATOM   1451 O O      . TYR A 1 178 ? 104.568 125.976 102.637 1.00 65.29  ? 169 TYR A O      1 
ATOM   1452 C CB     . TYR A 1 178 ? 103.735 128.975 103.382 1.00 65.29  ? 169 TYR A CB     1 
ATOM   1453 C CG     . TYR A 1 178 ? 104.019 130.372 103.865 1.00 65.29  ? 169 TYR A CG     1 
ATOM   1454 C CD1    . TYR A 1 178 ? 105.248 130.707 104.405 1.00 65.29  ? 169 TYR A CD1    1 
ATOM   1455 C CD2    . TYR A 1 178 ? 103.049 131.360 103.779 1.00 65.29  ? 169 TYR A CD2    1 
ATOM   1456 C CE1    . TYR A 1 178 ? 105.503 131.989 104.848 1.00 65.29  ? 169 TYR A CE1    1 
ATOM   1457 C CE2    . TYR A 1 178 ? 103.293 132.641 104.218 1.00 65.29  ? 169 TYR A CE2    1 
ATOM   1458 C CZ     . TYR A 1 178 ? 104.521 132.954 104.751 1.00 65.29  ? 169 TYR A CZ     1 
ATOM   1459 O OH     . TYR A 1 178 ? 104.760 134.238 105.188 1.00 65.29  ? 169 TYR A OH     1 
ATOM   1460 H H      . TYR A 1 178 ? 104.808 130.012 101.428 1.00 65.29  ? 169 TYR A H      1 
ATOM   1461 H HA     . TYR A 1 178 ? 105.608 128.205 103.072 1.00 65.29  ? 169 TYR A HA     1 
ATOM   1462 H HB2    . TYR A 1 178 ? 102.911 129.004 102.873 1.00 65.29  ? 169 TYR A HB2    1 
ATOM   1463 H HB3    . TYR A 1 178 ? 103.614 128.415 104.165 1.00 65.29  ? 169 TYR A HB3    1 
ATOM   1464 H HD1    . TYR A 1 178 ? 105.911 130.057 104.472 1.00 65.29  ? 169 TYR A HD1    1 
ATOM   1465 H HD2    . TYR A 1 178 ? 102.217 131.153 103.419 1.00 65.29  ? 169 TYR A HD2    1 
ATOM   1466 H HE1    . TYR A 1 178 ? 106.333 132.202 105.209 1.00 65.29  ? 169 TYR A HE1    1 
ATOM   1467 H HE2    . TYR A 1 178 ? 102.632 133.292 104.153 1.00 65.29  ? 169 TYR A HE2    1 
ATOM   1468 H HH     . TYR A 1 178 ? 104.087 134.720 105.044 1.00 65.29  ? 169 TYR A HH     1 
ATOM   1469 N N      . LEU A 1 179 ? 103.694 126.998 100.834 1.00 64.22  ? 170 LEU A N      1 
ATOM   1470 C CA     . LEU A 1 179 ? 103.137 125.790 100.244 1.00 64.22  ? 170 LEU A CA     1 
ATOM   1471 C C      . LEU A 1 179 ? 104.102 125.084 99.310  1.00 64.22  ? 170 LEU A C      1 
ATOM   1472 O O      . LEU A 1 179 ? 104.194 123.856 99.341  1.00 64.22  ? 170 LEU A O      1 
ATOM   1473 C CB     . LEU A 1 179 ? 101.853 126.130 99.482  1.00 64.22  ? 170 LEU A CB     1 
ATOM   1474 C CG     . LEU A 1 179 ? 101.054 124.956 98.922  1.00 64.22  ? 170 LEU A CG     1 
ATOM   1475 C CD1    . LEU A 1 179 ? 99.568  125.207 99.081  1.00 64.22  ? 170 LEU A CD1    1 
ATOM   1476 C CD2    . LEU A 1 179 ? 101.390 124.714 97.464  1.00 64.22  ? 170 LEU A CD2    1 
ATOM   1477 H H      . LEU A 1 179 ? 103.556 127.702 100.361 1.00 64.22  ? 170 LEU A H      1 
ATOM   1478 H HA     . LEU A 1 179 ? 102.905 125.172 100.952 1.00 64.22  ? 170 LEU A HA     1 
ATOM   1479 H HB2    . LEU A 1 179 ? 101.268 126.611 100.087 1.00 64.22  ? 170 LEU A HB2    1 
ATOM   1480 H HB3    . LEU A 1 179 ? 102.084 126.704 98.735  1.00 64.22  ? 170 LEU A HB3    1 
ATOM   1481 H HG     . LEU A 1 179 ? 101.282 124.156 99.421  1.00 64.22  ? 170 LEU A HG     1 
ATOM   1482 H HD11   . LEU A 1 179 ? 99.085  124.477 98.663  1.00 64.22  ? 170 LEU A HD11   1 
ATOM   1483 H HD12   . LEU A 1 179 ? 99.354  125.247 100.026 1.00 64.22  ? 170 LEU A HD12   1 
ATOM   1484 H HD13   . LEU A 1 179 ? 99.338  126.045 98.650  1.00 64.22  ? 170 LEU A HD13   1 
ATOM   1485 H HD21   . LEU A 1 179 ? 101.228 125.529 96.963  1.00 64.22  ? 170 LEU A HD21   1 
ATOM   1486 H HD22   . LEU A 1 179 ? 100.823 124.003 97.127  1.00 64.22  ? 170 LEU A HD22   1 
ATOM   1487 H HD23   . LEU A 1 179 ? 102.322 124.458 97.390  1.00 64.22  ? 170 LEU A HD23   1 
ATOM   1488 N N      . THR A 1 180 ? 104.830 125.828 98.481  1.00 64.29  ? 171 THR A N      1 
ATOM   1489 C CA     . THR A 1 180 ? 105.784 125.209 97.571  1.00 64.29  ? 171 THR A CA     1 
ATOM   1490 C C      . THR A 1 180 ? 106.983 124.682 98.348  1.00 64.29  ? 171 THR A C      1 
ATOM   1491 O O      . THR A 1 180 ? 107.226 123.472 98.379  1.00 64.29  ? 171 THR A O      1 
ATOM   1492 C CB     . THR A 1 180 ? 106.231 126.205 96.503  1.00 64.29  ? 171 THR A CB     1 
ATOM   1493 O OG1    . THR A 1 180 ? 106.597 127.440 97.126  1.00 64.29  ? 171 THR A OG1    1 
ATOM   1494 C CG2    . THR A 1 180 ? 105.106 126.456 95.514  1.00 64.29  ? 171 THR A CG2    1 
ATOM   1495 H H      . THR A 1 180 ? 104.791 126.685 98.430  1.00 64.29  ? 171 THR A H      1 
ATOM   1496 H HA     . THR A 1 180 ? 105.359 124.461 97.123  1.00 64.29  ? 171 THR A HA     1 
ATOM   1497 H HB     . THR A 1 180 ? 106.990 125.845 96.018  1.00 64.29  ? 171 THR A HB     1 
ATOM   1498 H HG1    . THR A 1 180 ? 105.904 127.845 97.373  1.00 64.29  ? 171 THR A HG1    1 
ATOM   1499 H HG21   . THR A 1 180 ? 104.359 126.879 95.964  1.00 64.29  ? 171 THR A HG21   1 
ATOM   1500 H HG22   . THR A 1 180 ? 105.412 127.035 94.799  1.00 64.29  ? 171 THR A HG22   1 
ATOM   1501 H HG23   . THR A 1 180 ? 104.810 125.615 95.135  1.00 64.29  ? 171 THR A HG23   1 
ATOM   1502 N N      . TYR A 1 181 ? 107.730 125.575 98.988  1.00 63.02  ? 172 TYR A N      1 
ATOM   1503 C CA     . TYR A 1 181 ? 108.746 125.160 99.933  1.00 63.02  ? 172 TYR A CA     1 
ATOM   1504 C C      . TYR A 1 181 ? 108.083 124.944 101.286 1.00 63.02  ? 172 TYR A C      1 
ATOM   1505 O O      . TYR A 1 181 ? 107.008 125.479 101.567 1.00 63.02  ? 172 TYR A O      1 
ATOM   1506 C CB     . TYR A 1 181 ? 109.847 126.216 100.025 1.00 63.02  ? 172 TYR A CB     1 
ATOM   1507 C CG     . TYR A 1 181 ? 111.086 125.785 100.772 1.00 63.02  ? 172 TYR A CG     1 
ATOM   1508 C CD1    . TYR A 1 181 ? 112.147 125.190 100.109 1.00 63.02  ? 172 TYR A CD1    1 
ATOM   1509 C CD2    . TYR A 1 181 ? 111.203 125.992 102.135 1.00 63.02  ? 172 TYR A CD2    1 
ATOM   1510 C CE1    . TYR A 1 181 ? 113.284 124.802 100.786 1.00 63.02  ? 172 TYR A CE1    1 
ATOM   1511 C CE2    . TYR A 1 181 ? 112.337 125.608 102.819 1.00 63.02  ? 172 TYR A CE2    1 
ATOM   1512 C CZ     . TYR A 1 181 ? 113.373 125.014 102.140 1.00 63.02  ? 172 TYR A CZ     1 
ATOM   1513 O OH     . TYR A 1 181 ? 114.503 124.630 102.817 1.00 63.02  ? 172 TYR A OH     1 
ATOM   1514 H H      . TYR A 1 181 ? 107.663 126.427 98.893  1.00 63.02  ? 172 TYR A H      1 
ATOM   1515 H HA     . TYR A 1 181 ? 109.145 124.325 99.643  1.00 63.02  ? 172 TYR A HA     1 
ATOM   1516 H HB2    . TYR A 1 181 ? 110.119 126.456 99.125  1.00 63.02  ? 172 TYR A HB2    1 
ATOM   1517 H HB3    . TYR A 1 181 ? 109.488 126.996 100.475 1.00 63.02  ? 172 TYR A HB3    1 
ATOM   1518 H HD1    . TYR A 1 181 ? 112.092 125.044 99.192  1.00 63.02  ? 172 TYR A HD1    1 
ATOM   1519 H HD2    . TYR A 1 181 ? 110.504 126.393 102.598 1.00 63.02  ? 172 TYR A HD2    1 
ATOM   1520 H HE1    . TYR A 1 181 ? 113.987 124.400 100.328 1.00 63.02  ? 172 TYR A HE1    1 
ATOM   1521 H HE2    . TYR A 1 181 ? 112.399 125.750 103.735 1.00 63.02  ? 172 TYR A HE2    1 
ATOM   1522 H HH     . TYR A 1 181 ? 115.056 124.293 102.282 1.00 63.02  ? 172 TYR A HH     1 
ATOM   1523 N N      . GLY A 1 182 ? 108.717 124.141 102.125 1.00 61.96  ? 173 GLY A N      1 
ATOM   1524 C CA     . GLY A 1 182 ? 108.093 123.825 103.392 1.00 61.96  ? 173 GLY A CA     1 
ATOM   1525 C C      . GLY A 1 182 ? 107.109 122.684 103.276 1.00 61.96  ? 173 GLY A C      1 
ATOM   1526 O O      . GLY A 1 182 ? 107.518 121.526 103.299 1.00 61.96  ? 173 GLY A O      1 
ATOM   1527 H H      . GLY A 1 182 ? 109.487 123.781 101.994 1.00 61.96  ? 173 GLY A H      1 
ATOM   1528 H HA2    . GLY A 1 182 ? 108.772 123.558 104.028 1.00 61.96  ? 173 GLY A HA2    1 
ATOM   1529 H HA3    . GLY A 1 182 ? 107.627 124.601 103.740 1.00 61.96  ? 173 GLY A HA3    1 
ATOM   1530 N N      . ILE A 1 183 ? 105.813 122.984 103.167 1.00 60.66  ? 174 ILE A N      1 
ATOM   1531 C CA     . ILE A 1 183 ? 104.803 121.926 103.186 1.00 60.66  ? 174 ILE A CA     1 
ATOM   1532 C C      . ILE A 1 183 ? 105.174 120.813 102.212 1.00 60.66  ? 174 ILE A C      1 
ATOM   1533 O O      . ILE A 1 183 ? 105.432 119.673 102.613 1.00 60.66  ? 174 ILE A O      1 
ATOM   1534 C CB     . ILE A 1 183 ? 103.414 122.503 102.869 1.00 60.66  ? 174 ILE A CB     1 
ATOM   1535 C CG1    . ILE A 1 183 ? 102.957 123.421 104.004 1.00 60.66  ? 174 ILE A CG1    1 
ATOM   1536 C CG2    . ILE A 1 183 ? 102.415 121.378 102.647 1.00 60.66  ? 174 ILE A CG2    1 
ATOM   1537 C CD1    . ILE A 1 183 ? 101.705 124.211 103.694 1.00 60.66  ? 174 ILE A CD1    1 
ATOM   1538 H H      . ILE A 1 183 ? 105.495 123.779 103.085 1.00 60.66  ? 174 ILE A H      1 
ATOM   1539 H HA     . ILE A 1 183 ? 104.768 121.541 104.075 1.00 60.66  ? 174 ILE A HA     1 
ATOM   1540 H HB     . ILE A 1 183 ? 103.475 123.026 102.054 1.00 60.66  ? 174 ILE A HB     1 
ATOM   1541 H HG12   . ILE A 1 183 ? 102.779 122.881 104.790 1.00 60.66  ? 174 ILE A HG12   1 
ATOM   1542 H HG13   . ILE A 1 183 ? 103.665 124.055 104.198 1.00 60.66  ? 174 ILE A HG13   1 
ATOM   1543 H HG21   . ILE A 1 183 ? 102.555 120.999 101.765 1.00 60.66  ? 174 ILE A HG21   1 
ATOM   1544 H HG22   . ILE A 1 183 ? 101.514 121.730 102.708 1.00 60.66  ? 174 ILE A HG22   1 
ATOM   1545 H HG23   . ILE A 1 183 ? 102.548 120.699 103.326 1.00 60.66  ? 174 ILE A HG23   1 
ATOM   1546 H HD11   . ILE A 1 183 ? 101.588 124.893 104.374 1.00 60.66  ? 174 ILE A HD11   1 
ATOM   1547 H HD12   . ILE A 1 183 ? 100.941 123.613 103.696 1.00 60.66  ? 174 ILE A HD12   1 
ATOM   1548 H HD13   . ILE A 1 183 ? 101.799 124.626 102.824 1.00 60.66  ? 174 ILE A HD13   1 
ATOM   1549 N N      . ILE A 1 184 ? 105.243 121.137 100.918 1.00 62.97  ? 175 ILE A N      1 
ATOM   1550 C CA     . ILE A 1 184 ? 105.439 120.104 99.902  1.00 62.97  ? 175 ILE A CA     1 
ATOM   1551 C C      . ILE A 1 184 ? 106.831 119.492 100.011 1.00 62.97  ? 175 ILE A C      1 
ATOM   1552 O O      . ILE A 1 184 ? 106.994 118.263 100.013 1.00 62.97  ? 175 ILE A O      1 
ATOM   1553 C CB     . ILE A 1 184 ? 105.191 120.682 98.498  1.00 62.97  ? 175 ILE A CB     1 
ATOM   1554 C CG1    . ILE A 1 184 ? 103.709 121.012 98.319  1.00 62.97  ? 175 ILE A CG1    1 
ATOM   1555 C CG2    . ILE A 1 184 ? 105.652 119.699 97.437  1.00 62.97  ? 175 ILE A CG2    1 
ATOM   1556 C CD1    . ILE A 1 184 ? 103.396 121.778 97.052  1.00 62.97  ? 175 ILE A CD1    1 
ATOM   1557 H H      . ILE A 1 184 ? 105.179 121.937 100.608 1.00 62.97  ? 175 ILE A H      1 
ATOM   1558 H HA     . ILE A 1 184 ? 104.792 119.396 100.048 1.00 62.97  ? 175 ILE A HA     1 
ATOM   1559 H HB     . ILE A 1 184 ? 105.704 121.500 98.406  1.00 62.97  ? 175 ILE A HB     1 
ATOM   1560 H HG12   . ILE A 1 184 ? 103.208 120.182 98.293  1.00 62.97  ? 175 ILE A HG12   1 
ATOM   1561 H HG13   . ILE A 1 184 ? 103.415 121.549 99.071  1.00 62.97  ? 175 ILE A HG13   1 
ATOM   1562 H HG21   . ILE A 1 184 ? 105.271 119.947 96.581  1.00 62.97  ? 175 ILE A HG21   1 
ATOM   1563 H HG22   . ILE A 1 184 ? 106.619 119.721 97.380  1.00 62.97  ? 175 ILE A HG22   1 
ATOM   1564 H HG23   . ILE A 1 184 ? 105.354 118.810 97.684  1.00 62.97  ? 175 ILE A HG23   1 
ATOM   1565 H HD11   . ILE A 1 184 ? 104.030 122.506 96.957  1.00 62.97  ? 175 ILE A HD11   1 
ATOM   1566 H HD12   . ILE A 1 184 ? 102.494 122.131 97.114  1.00 62.97  ? 175 ILE A HD12   1 
ATOM   1567 H HD13   . ILE A 1 184 ? 103.463 121.179 96.292  1.00 62.97  ? 175 ILE A HD13   1 
ATOM   1568 N N      . PHE A 1 185 ? 107.856 120.338 100.105 1.00 61.74  ? 176 PHE A N      1 
ATOM   1569 C CA     . PHE A 1 185 ? 109.224 119.836 100.099 1.00 61.74  ? 176 PHE A CA     1 
ATOM   1570 C C      . PHE A 1 185 ? 109.467 118.895 101.271 1.00 61.74  ? 176 PHE A C      1 
ATOM   1571 O O      . PHE A 1 185 ? 110.051 117.821 101.105 1.00 61.74  ? 176 PHE A O      1 
ATOM   1572 C CB     . PHE A 1 185 ? 110.207 121.005 100.132 1.00 61.74  ? 176 PHE A CB     1 
ATOM   1573 C CG     . PHE A 1 185 ? 111.641 120.585 100.261 1.00 61.74  ? 176 PHE A CG     1 
ATOM   1574 C CD1    . PHE A 1 185 ? 112.289 119.957 99.214  1.00 61.74  ? 176 PHE A CD1    1 
ATOM   1575 C CD2    . PHE A 1 185 ? 112.343 120.826 101.428 1.00 61.74  ? 176 PHE A CD2    1 
ATOM   1576 C CE1    . PHE A 1 185 ? 113.608 119.573 99.330  1.00 61.74  ? 176 PHE A CE1    1 
ATOM   1577 C CE2    . PHE A 1 185 ? 113.661 120.444 101.548 1.00 61.74  ? 176 PHE A CE2    1 
ATOM   1578 C CZ     . PHE A 1 185 ? 114.294 119.818 100.497 1.00 61.74  ? 176 PHE A CZ     1 
ATOM   1579 H H      . PHE A 1 185 ? 107.786 121.192 100.174 1.00 61.74  ? 176 PHE A H      1 
ATOM   1580 H HA     . PHE A 1 185 ? 109.374 119.339 99.279  1.00 61.74  ? 176 PHE A HA     1 
ATOM   1581 H HB2    . PHE A 1 185 ? 110.119 121.509 99.308  1.00 61.74  ? 176 PHE A HB2    1 
ATOM   1582 H HB3    . PHE A 1 185 ? 109.994 121.572 100.889 1.00 61.74  ? 176 PHE A HB3    1 
ATOM   1583 H HD1    . PHE A 1 185 ? 111.829 119.790 98.423  1.00 61.74  ? 176 PHE A HD1    1 
ATOM   1584 H HD2    . PHE A 1 185 ? 111.920 121.249 102.139 1.00 61.74  ? 176 PHE A HD2    1 
ATOM   1585 H HE1    . PHE A 1 185 ? 114.033 119.150 98.620  1.00 61.74  ? 176 PHE A HE1    1 
ATOM   1586 H HE2    . PHE A 1 185 ? 114.123 120.610 102.337 1.00 61.74  ? 176 PHE A HE2    1 
ATOM   1587 H HZ     . PHE A 1 185 ? 115.184 119.560 100.578 1.00 61.74  ? 176 PHE A HZ     1 
ATOM   1588 N N      . ALA A 1 186 ? 109.016 119.277 102.467 1.00 60.14  ? 177 ALA A N      1 
ATOM   1589 C CA     . ALA A 1 186 ? 109.236 118.451 103.647 1.00 60.14  ? 177 ALA A CA     1 
ATOM   1590 C C      . ALA A 1 186 ? 108.336 117.224 103.645 1.00 60.14  ? 177 ALA A C      1 
ATOM   1591 O O      . ALA A 1 186 ? 108.748 116.151 104.100 1.00 60.14  ? 177 ALA A O      1 
ATOM   1592 C CB     . ALA A 1 186 ? 109.008 119.280 104.908 1.00 60.14  ? 177 ALA A CB     1 
ATOM   1593 H H      . ALA A 1 186 ? 108.586 120.005 102.619 1.00 60.14  ? 177 ALA A H      1 
ATOM   1594 H HA     . ALA A 1 186 ? 110.157 118.146 103.653 1.00 60.14  ? 177 ALA A HA     1 
ATOM   1595 H HB1    . ALA A 1 186 ? 109.647 120.010 104.924 1.00 60.14  ? 177 ALA A HB1    1 
ATOM   1596 H HB2    . ALA A 1 186 ? 108.104 119.631 104.891 1.00 60.14  ? 177 ALA A HB2    1 
ATOM   1597 H HB3    . ALA A 1 186 ? 109.131 118.715 105.686 1.00 60.14  ? 177 ALA A HB3    1 
ATOM   1598 N N      . CYS A 1 187 ? 107.100 117.352 103.155 1.00 60.01  ? 178 CYS A N      1 
ATOM   1599 C CA     . CYS A 1 187 ? 106.253 116.174 103.047 1.00 60.01  ? 178 CYS A CA     1 
ATOM   1600 C C      . CYS A 1 187 ? 106.861 115.161 102.095 1.00 60.01  ? 178 CYS A C      1 
ATOM   1601 O O      . CYS A 1 187 ? 106.579 113.962 102.198 1.00 60.01  ? 178 CYS A O      1 
ATOM   1602 C CB     . CYS A 1 187 ? 104.853 116.570 102.585 1.00 60.01  ? 178 CYS A CB     1 
ATOM   1603 S SG     . CYS A 1 187 ? 103.626 115.264 102.777 1.00 60.01  ? 178 CYS A SG     1 
ATOM   1604 H H      . CYS A 1 187 ? 106.743 118.086 102.886 1.00 60.01  ? 178 CYS A H      1 
ATOM   1605 H HA     . CYS A 1 187 ? 106.176 115.758 103.920 1.00 60.01  ? 178 CYS A HA     1 
ATOM   1606 H HB2    . CYS A 1 187 ? 104.558 117.332 103.108 1.00 60.01  ? 178 CYS A HB2    1 
ATOM   1607 H HB3    . CYS A 1 187 ? 104.887 116.809 101.645 1.00 60.01  ? 178 CYS A HB3    1 
ATOM   1608 H HG     . CYS A 1 187 ? 103.976 114.305 102.147 1.00 60.01  ? 178 CYS A HG     1 
ATOM   1609 N N      . GLY A 1 188 ? 107.684 115.621 101.157 1.00 61.37  ? 179 GLY A N      1 
ATOM   1610 C CA     . GLY A 1 188 ? 108.458 114.708 100.337 1.00 61.37  ? 179 GLY A CA     1 
ATOM   1611 C C      . GLY A 1 188 ? 109.690 114.168 101.041 1.00 61.37  ? 179 GLY A C      1 
ATOM   1612 O O      . GLY A 1 188 ? 109.987 112.970 100.973 1.00 61.37  ? 179 GLY A O      1 
ATOM   1613 H H      . GLY A 1 188 ? 107.808 116.453 100.978 1.00 61.37  ? 179 GLY A H      1 
ATOM   1614 H HA2    . GLY A 1 188 ? 107.901 113.957 100.078 1.00 61.37  ? 179 GLY A HA2    1 
ATOM   1615 H HA3    . GLY A 1 188 ? 108.744 115.168 99.532  1.00 61.37  ? 179 GLY A HA3    1 
ATOM   1616 N N      . CYS A 1 189 ? 110.415 115.056 101.724 1.00 61.74  ? 180 CYS A N      1 
ATOM   1617 C CA     . CYS A 1 189 ? 111.680 114.675 102.345 1.00 61.74  ? 180 CYS A CA     1 
ATOM   1618 C C      . CYS A 1 189 ? 111.476 113.644 103.444 1.00 61.74  ? 180 CYS A C      1 
ATOM   1619 O O      . CYS A 1 189 ? 112.281 112.720 103.593 1.00 61.74  ? 180 CYS A O      1 
ATOM   1620 C CB     . CYS A 1 189 ? 112.383 115.911 102.904 1.00 61.74  ? 180 CYS A CB     1 
ATOM   1621 S SG     . CYS A 1 189 ? 113.144 116.965 101.655 1.00 61.74  ? 180 CYS A SG     1 
ATOM   1622 H H      . CYS A 1 189 ? 110.196 115.880 101.839 1.00 61.74  ? 180 CYS A H      1 
ATOM   1623 H HA     . CYS A 1 189 ? 112.258 114.284 101.671 1.00 61.74  ? 180 CYS A HA     1 
ATOM   1624 H HB2    . CYS A 1 189 ? 111.734 116.447 103.387 1.00 61.74  ? 180 CYS A HB2    1 
ATOM   1625 H HB3    . CYS A 1 189 ? 113.082 115.621 103.510 1.00 61.74  ? 180 CYS A HB3    1 
ATOM   1626 H HG     . CYS A 1 189 ? 112.331 117.289 100.835 1.00 61.74  ? 180 CYS A HG     1 
ATOM   1627 N N      . SER A 1 190 ? 110.425 113.803 104.250 1.00 59.22  ? 181 SER A N      1 
ATOM   1628 C CA     . SER A 1 190 ? 110.168 112.835 105.310 1.00 59.22  ? 181 SER A CA     1 
ATOM   1629 C C      . SER A 1 190 ? 109.917 111.451 104.733 1.00 59.22  ? 181 SER A C      1 
ATOM   1630 O O      . SER A 1 190 ? 110.449 110.454 105.235 1.00 59.22  ? 181 SER A O      1 
ATOM   1631 C CB     . SER A 1 190 ? 108.979 113.283 106.154 1.00 59.22  ? 181 SER A CB     1 
ATOM   1632 O OG     . SER A 1 190 ? 108.643 112.294 107.109 1.00 59.22  ? 181 SER A OG     1 
ATOM   1633 H H      . SER A 1 190 ? 109.858 114.448 104.205 1.00 59.22  ? 181 SER A H      1 
ATOM   1634 H HA     . SER A 1 190 ? 110.946 112.784 105.888 1.00 59.22  ? 181 SER A HA     1 
ATOM   1635 H HB2    . SER A 1 190 ? 109.211 114.103 106.615 1.00 59.22  ? 181 SER A HB2    1 
ATOM   1636 H HB3    . SER A 1 190 ? 108.217 113.432 105.573 1.00 59.22  ? 181 SER A HB3    1 
ATOM   1637 H HG     . SER A 1 190 ? 108.324 111.618 106.726 1.00 59.22  ? 181 SER A HG     1 
ATOM   1638 N N      . PHE A 1 191 ? 109.106 111.371 103.678 1.00 59.72  ? 182 PHE A N      1 
ATOM   1639 C CA     . PHE A 1 191 ? 108.884 110.090 103.020 1.00 59.72  ? 182 PHE A CA     1 
ATOM   1640 C C      . PHE A 1 191 ? 110.184 109.533 102.464 1.00 59.72  ? 182 PHE A C      1 
ATOM   1641 O O      . PHE A 1 191 ? 110.432 108.325 102.535 1.00 59.72  ? 182 PHE A O      1 
ATOM   1642 C CB     . PHE A 1 191 ? 107.853 110.246 101.905 1.00 59.72  ? 182 PHE A CB     1 
ATOM   1643 C CG     . PHE A 1 191 ? 106.447 110.025 102.354 1.00 59.72  ? 182 PHE A CG     1 
ATOM   1644 C CD1    . PHE A 1 191 ? 105.859 110.871 103.272 1.00 59.72  ? 182 PHE A CD1    1 
ATOM   1645 C CD2    . PHE A 1 191 ? 105.709 108.974 101.854 1.00 59.72  ? 182 PHE A CD2    1 
ATOM   1646 C CE1    . PHE A 1 191 ? 104.559 110.668 103.687 1.00 59.72  ? 182 PHE A CE1    1 
ATOM   1647 C CE2    . PHE A 1 191 ? 104.411 108.766 102.263 1.00 59.72  ? 182 PHE A CE2    1 
ATOM   1648 C CZ     . PHE A 1 191 ? 103.836 109.614 103.181 1.00 59.72  ? 182 PHE A CZ     1 
ATOM   1649 H H      . PHE A 1 191 ? 108.681 112.033 103.331 1.00 59.72  ? 182 PHE A H      1 
ATOM   1650 H HA     . PHE A 1 191 ? 108.536 109.457 103.667 1.00 59.72  ? 182 PHE A HA     1 
ATOM   1651 H HB2    . PHE A 1 191 ? 107.912 111.146 101.547 1.00 59.72  ? 182 PHE A HB2    1 
ATOM   1652 H HB3    . PHE A 1 191 ? 108.047 109.601 101.207 1.00 59.72  ? 182 PHE A HB3    1 
ATOM   1653 H HD1    . PHE A 1 191 ? 106.345 111.585 103.618 1.00 59.72  ? 182 PHE A HD1    1 
ATOM   1654 H HD2    . PHE A 1 191 ? 106.093 108.397 101.233 1.00 59.72  ? 182 PHE A HD2    1 
ATOM   1655 H HE1    . PHE A 1 191 ? 104.173 111.242 104.307 1.00 59.72  ? 182 PHE A HE1    1 
ATOM   1656 H HE2    . PHE A 1 191 ? 103.924 108.053 101.919 1.00 59.72  ? 182 PHE A HE2    1 
ATOM   1657 H HZ     . PHE A 1 191 ? 102.959 109.475 103.458 1.00 59.72  ? 182 PHE A HZ     1 
ATOM   1658 N N      . ALA A 1 192 ? 111.023 110.397 101.896 1.00 61.24  ? 183 ALA A N      1 
ATOM   1659 C CA     . ALA A 1 192 ? 112.288 109.929 101.342 1.00 61.24  ? 183 ALA A CA     1 
ATOM   1660 C C      . ALA A 1 192 ? 113.187 109.352 102.427 1.00 61.24  ? 183 ALA A C      1 
ATOM   1661 O O      . ALA A 1 192 ? 113.828 108.314 102.228 1.00 61.24  ? 183 ALA A O      1 
ATOM   1662 C CB     . ALA A 1 192 ? 112.997 111.072 100.619 1.00 61.24  ? 183 ALA A CB     1 
ATOM   1663 H H      . ALA A 1 192 ? 110.887 111.243 101.821 1.00 61.24  ? 183 ALA A H      1 
ATOM   1664 H HA     . ALA A 1 192 ? 112.110 109.228 100.696 1.00 61.24  ? 183 ALA A HA     1 
ATOM   1665 H HB1    . ALA A 1 192 ? 113.830 110.740 100.249 1.00 61.24  ? 183 ALA A HB1    1 
ATOM   1666 H HB2    . ALA A 1 192 ? 113.177 111.784 101.253 1.00 61.24  ? 183 ALA A HB2    1 
ATOM   1667 H HB3    . ALA A 1 192 ? 112.425 111.398 99.908  1.00 61.24  ? 183 ALA A HB3    1 
ATOM   1668 N N      . TYR A 1 193 ? 113.240 110.006 103.584 1.00 60.15  ? 184 TYR A N      1 
ATOM   1669 C CA     . TYR A 1 193 ? 114.244 109.696 104.592 1.00 60.15  ? 184 TYR A CA     1 
ATOM   1670 C C      . TYR A 1 193 ? 113.820 108.589 105.546 1.00 60.15  ? 184 TYR A C      1 
ATOM   1671 O O      . TYR A 1 193 ? 114.659 107.780 105.953 1.00 60.15  ? 184 TYR A O      1 
ATOM   1672 C CB     . TYR A 1 193 ? 114.583 110.954 105.392 1.00 60.15  ? 184 TYR A CB     1 
ATOM   1673 C CG     . TYR A 1 193 ? 115.428 110.685 106.611 1.00 60.15  ? 184 TYR A CG     1 
ATOM   1674 C CD1    . TYR A 1 193 ? 116.722 110.208 106.490 1.00 60.15  ? 184 TYR A CD1    1 
ATOM   1675 C CD2    . TYR A 1 193 ? 114.932 110.916 107.884 1.00 60.15  ? 184 TYR A CD2    1 
ATOM   1676 C CE1    . TYR A 1 193 ? 117.497 109.962 107.601 1.00 60.15  ? 184 TYR A CE1    1 
ATOM   1677 C CE2    . TYR A 1 193 ? 115.700 110.675 109.001 1.00 60.15  ? 184 TYR A CE2    1 
ATOM   1678 C CZ     . TYR A 1 193 ? 116.981 110.199 108.855 1.00 60.15  ? 184 TYR A CZ     1 
ATOM   1679 O OH     . TYR A 1 193 ? 117.747 109.958 109.970 1.00 60.15  ? 184 TYR A OH     1 
ATOM   1680 H H      . TYR A 1 193 ? 112.701 110.637 103.809 1.00 60.15  ? 184 TYR A H      1 
ATOM   1681 H HA     . TYR A 1 193 ? 115.052 109.404 104.144 1.00 60.15  ? 184 TYR A HA     1 
ATOM   1682 H HB2    . TYR A 1 193 ? 115.074 111.566 104.822 1.00 60.15  ? 184 TYR A HB2    1 
ATOM   1683 H HB3    . TYR A 1 193 ? 113.758 111.370 105.687 1.00 60.15  ? 184 TYR A HB3    1 
ATOM   1684 H HD1    . TYR A 1 193 ? 117.072 110.047 105.643 1.00 60.15  ? 184 TYR A HD1    1 
ATOM   1685 H HD2    . TYR A 1 193 ? 114.066 111.238 107.985 1.00 60.15  ? 184 TYR A HD2    1 
ATOM   1686 H HE1    . TYR A 1 193 ? 118.364 109.640 107.505 1.00 60.15  ? 184 TYR A HE1    1 
ATOM   1687 H HE2    . TYR A 1 193 ? 115.354 110.834 109.850 1.00 60.15  ? 184 TYR A HE2    1 
ATOM   1688 H HH     . TYR A 1 193 ? 117.314 110.151 110.663 1.00 60.15  ? 184 TYR A HH     1 
ATOM   1689 N N      . GLN A 1 194 ? 112.547 108.528 105.925 1.00 60.44  ? 185 GLN A N      1 
ATOM   1690 C CA     . GLN A 1 194 ? 112.123 107.538 106.914 1.00 60.44  ? 185 GLN A CA     1 
ATOM   1691 C C      . GLN A 1 194 ? 112.477 106.110 106.526 1.00 60.44  ? 185 GLN A C      1 
ATOM   1692 O O      . GLN A 1 194 ? 113.030 105.388 107.371 1.00 60.44  ? 185 GLN A O      1 
ATOM   1693 C CB     . GLN A 1 194 ? 110.615 107.669 107.156 1.00 60.44  ? 185 GLN A CB     1 
ATOM   1694 C CG     . GLN A 1 194 ? 110.116 106.872 108.350 1.00 60.44  ? 185 GLN A CG     1 
ATOM   1695 C CD     . GLN A 1 194 ? 109.972 105.394 108.054 1.00 60.44  ? 185 GLN A CD     1 
ATOM   1696 O OE1    . GLN A 1 194 ? 109.952 104.982 106.896 1.00 60.44  ? 185 GLN A OE1    1 
ATOM   1697 N NE2    . GLN A 1 194 ? 109.875 104.587 109.102 1.00 60.44  ? 185 GLN A NE2    1 
ATOM   1698 H H      . GLN A 1 194 ? 111.918 109.038 105.633 1.00 60.44  ? 185 GLN A H      1 
ATOM   1699 H HA     . GLN A 1 194 ? 112.571 107.731 107.752 1.00 60.44  ? 185 GLN A HA     1 
ATOM   1700 H HB2    . GLN A 1 194 ? 110.404 108.603 107.314 1.00 60.44  ? 185 GLN A HB2    1 
ATOM   1701 H HB3    . GLN A 1 194 ? 110.143 107.355 106.369 1.00 60.44  ? 185 GLN A HB3    1 
ATOM   1702 H HG2    . GLN A 1 194 ? 110.748 106.970 109.079 1.00 60.44  ? 185 GLN A HG2    1 
ATOM   1703 H HG3    . GLN A 1 194 ? 109.248 107.212 108.618 1.00 60.44  ? 185 GLN A HG3    1 
ATOM   1704 H HE21   . GLN A 1 194 ? 109.894 104.912 109.898 1.00 60.44  ? 185 GLN A HE21   1 
ATOM   1705 H HE22   . GLN A 1 194 ? 109.792 103.739 108.986 1.00 60.44  ? 185 GLN A HE22   1 
ATOM   1706 N N      . PRO A 1 195 ? 112.200 105.634 105.309 1.00 60.36  ? 186 PRO A N      1 
ATOM   1707 C CA     . PRO A 1 195 ? 112.477 104.222 105.002 1.00 60.36  ? 186 PRO A CA     1 
ATOM   1708 C C      . PRO A 1 195 ? 113.951 103.870 105.032 1.00 60.36  ? 186 PRO A C      1 
ATOM   1709 O O      . PRO A 1 195 ? 114.281 102.678 105.032 1.00 60.36  ? 186 PRO A O      1 
ATOM   1710 C CB     . PRO A 1 195 ? 111.888 104.043 103.597 1.00 60.36  ? 186 PRO A CB     1 
ATOM   1711 C CG     . PRO A 1 195 ? 111.899 105.395 103.012 1.00 60.36  ? 186 PRO A CG     1 
ATOM   1712 C CD     . PRO A 1 195 ? 111.648 106.343 104.143 1.00 60.36  ? 186 PRO A CD     1 
ATOM   1713 H HA     . PRO A 1 195 ? 112.000 103.647 105.620 1.00 60.36  ? 186 PRO A HA     1 
ATOM   1714 H HB2    . PRO A 1 195 ? 112.446 103.440 103.081 1.00 60.36  ? 186 PRO A HB2    1 
ATOM   1715 H HB3    . PRO A 1 195 ? 110.982 103.704 103.662 1.00 60.36  ? 186 PRO A HB3    1 
ATOM   1716 H HG2    . PRO A 1 195 ? 112.765 105.567 102.610 1.00 60.36  ? 186 PRO A HG2    1 
ATOM   1717 H HG3    . PRO A 1 195 ? 111.196 105.465 102.347 1.00 60.36  ? 186 PRO A HG3    1 
ATOM   1718 H HD2    . PRO A 1 195 ? 112.123 107.171 103.980 1.00 60.36  ? 186 PRO A HD2    1 
ATOM   1719 H HD3    . PRO A 1 195 ? 110.696 106.493 104.255 1.00 60.36  ? 186 PRO A HD3    1 
ATOM   1720 N N      . SER A 1 196 ? 114.847 104.856 105.060 1.00 60.37  ? 187 SER A N      1 
ATOM   1721 C CA     . SER A 1 196 ? 116.272 104.549 105.061 1.00 60.37  ? 187 SER A CA     1 
ATOM   1722 C C      . SER A 1 196 ? 116.661 103.728 106.282 1.00 60.37  ? 187 SER A C      1 
ATOM   1723 O O      . SER A 1 196 ? 117.497 102.825 106.187 1.00 60.37  ? 187 SER A O      1 
ATOM   1724 C CB     . SER A 1 196 ? 117.088 105.839 105.011 1.00 60.37  ? 187 SER A CB     1 
ATOM   1725 O OG     . SER A 1 196 ? 118.465 105.566 105.195 1.00 60.37  ? 187 SER A OG     1 
ATOM   1726 H H      . SER A 1 196 ? 114.659 105.695 105.078 1.00 60.37  ? 187 SER A H      1 
ATOM   1727 H HA     . SER A 1 196 ? 116.484 104.029 104.271 1.00 60.37  ? 187 SER A HA     1 
ATOM   1728 H HB2    . SER A 1 196 ? 116.961 106.259 104.146 1.00 60.37  ? 187 SER A HB2    1 
ATOM   1729 H HB3    . SER A 1 196 ? 116.786 106.432 105.716 1.00 60.37  ? 187 SER A HB3    1 
ATOM   1730 H HG     . SER A 1 196 ? 118.906 106.280 105.161 1.00 60.37  ? 187 SER A HG     1 
ATOM   1731 N N      . LEU A 1 197 ? 116.083 104.040 107.442 1.00 61.06  ? 188 LEU A N      1 
ATOM   1732 C CA     . LEU A 1 197 ? 116.453 103.330 108.662 1.00 61.06  ? 188 LEU A CA     1 
ATOM   1733 C C      . LEU A 1 197 ? 116.016 101.871 108.611 1.00 61.06  ? 188 LEU A C      1 
ATOM   1734 O O      . LEU A 1 197 ? 116.760 100.975 109.034 1.00 61.06  ? 188 LEU A O      1 
ATOM   1735 C CB     . LEU A 1 197 ? 115.837 104.027 109.874 1.00 61.06  ? 188 LEU A CB     1 
ATOM   1736 C CG     . LEU A 1 197 ? 116.020 105.543 109.933 1.00 61.06  ? 188 LEU A CG     1 
ATOM   1737 C CD1    . LEU A 1 197 ? 115.415 106.092 111.210 1.00 61.06  ? 188 LEU A CD1    1 
ATOM   1738 C CD2    . LEU A 1 197 ? 117.486 105.920 109.828 1.00 61.06  ? 188 LEU A CD2    1 
ATOM   1739 H H      . LEU A 1 197 ? 115.483 104.646 107.546 1.00 61.06  ? 188 LEU A H      1 
ATOM   1740 H HA     . LEU A 1 197 ? 117.417 103.350 108.761 1.00 61.06  ? 188 LEU A HA     1 
ATOM   1741 H HB2    . LEU A 1 197 ? 114.883 103.850 109.876 1.00 61.06  ? 188 LEU A HB2    1 
ATOM   1742 H HB3    . LEU A 1 197 ? 116.236 103.655 110.676 1.00 61.06  ? 188 LEU A HB3    1 
ATOM   1743 H HG     . LEU A 1 197 ? 115.553 105.948 109.185 1.00 61.06  ? 188 LEU A HG     1 
ATOM   1744 H HD11   . LEU A 1 197 ? 115.554 107.051 111.238 1.00 61.06  ? 188 LEU A HD11   1 
ATOM   1745 H HD12   . LEU A 1 197 ? 115.848 105.672 111.969 1.00 61.06  ? 188 LEU A HD12   1 
ATOM   1746 H HD13   . LEU A 1 197 ? 114.466 105.894 111.219 1.00 61.06  ? 188 LEU A HD13   1 
ATOM   1747 H HD21   . LEU A 1 197 ? 117.809 105.692 108.942 1.00 61.06  ? 188 LEU A HD21   1 
ATOM   1748 H HD22   . LEU A 1 197 ? 117.986 105.430 110.499 1.00 61.06  ? 188 LEU A HD22   1 
ATOM   1749 H HD23   . LEU A 1 197 ? 117.577 106.874 109.976 1.00 61.06  ? 188 LEU A HD23   1 
ATOM   1750 N N      . VAL A 1 198 ? 114.808 101.612 108.108 1.00 62.25  ? 189 VAL A N      1 
ATOM   1751 C CA     . VAL A 1 198 ? 114.289 100.250 108.097 1.00 62.25  ? 189 VAL A CA     1 
ATOM   1752 C C      . VAL A 1 198 ? 115.169 99.343  107.253 1.00 62.25  ? 189 VAL A C      1 
ATOM   1753 O O      . VAL A 1 198 ? 115.234 98.132  107.495 1.00 62.25  ? 189 VAL A O      1 
ATOM   1754 C CB     . VAL A 1 198 ? 112.832 100.239 107.598 1.00 62.25  ? 189 VAL A CB     1 
ATOM   1755 C CG1    . VAL A 1 198 ? 112.366 98.813  107.350 1.00 62.25  ? 189 VAL A CG1    1 
ATOM   1756 C CG2    . VAL A 1 198 ? 111.928 100.932 108.603 1.00 62.25  ? 189 VAL A CG2    1 
ATOM   1757 H H      . VAL A 1 198 ? 114.279 102.201 107.772 1.00 62.25  ? 189 VAL A H      1 
ATOM   1758 H HA     . VAL A 1 198 ? 114.294 99.907  109.004 1.00 62.25  ? 189 VAL A HA     1 
ATOM   1759 H HB     . VAL A 1 198 ? 112.780 100.724 106.760 1.00 62.25  ? 189 VAL A HB     1 
ATOM   1760 H HG11   . VAL A 1 198 ? 112.726 98.503  106.504 1.00 62.25  ? 189 VAL A HG11   1 
ATOM   1761 H HG12   . VAL A 1 198 ? 111.397 98.801  107.318 1.00 62.25  ? 189 VAL A HG12   1 
ATOM   1762 H HG13   . VAL A 1 198 ? 112.678 98.248  108.073 1.00 62.25  ? 189 VAL A HG13   1 
ATOM   1763 H HG21   . VAL A 1 198 ? 111.018 100.920 108.268 1.00 62.25  ? 189 VAL A HG21   1 
ATOM   1764 H HG22   . VAL A 1 198 ? 111.976 100.459 109.449 1.00 62.25  ? 189 VAL A HG22   1 
ATOM   1765 H HG23   . VAL A 1 198 ? 112.226 101.848 108.717 1.00 62.25  ? 189 VAL A HG23   1 
ATOM   1766 N N      . ILE A 1 199 ? 115.856 99.898  106.256 1.00 62.97  ? 190 ILE A N      1 
ATOM   1767 C CA     . ILE A 1 199 ? 116.717 99.092  105.401 1.00 62.97  ? 190 ILE A CA     1 
ATOM   1768 C C      . ILE A 1 199 ? 118.185 99.162  105.809 1.00 62.97  ? 190 ILE A C      1 
ATOM   1769 O O      . ILE A 1 199 ? 118.948 98.242  105.479 1.00 62.97  ? 190 ILE A O      1 
ATOM   1770 C CB     . ILE A 1 199 ? 116.549 99.490  103.921 1.00 62.97  ? 190 ILE A CB     1 
ATOM   1771 C CG1    . ILE A 1 199 ? 115.137 99.145  103.439 1.00 62.97  ? 190 ILE A CG1    1 
ATOM   1772 C CG2    . ILE A 1 199 ? 117.582 98.791  103.061 1.00 62.97  ? 190 ILE A CG2    1 
ATOM   1773 C CD1    . ILE A 1 199 ? 114.767 97.675  103.571 1.00 62.97  ? 190 ILE A CD1    1 
ATOM   1774 H H      . ILE A 1 199 ? 115.842 100.734 106.055 1.00 62.97  ? 190 ILE A H      1 
ATOM   1775 H HA     . ILE A 1 199 ? 116.450 98.165  105.486 1.00 62.97  ? 190 ILE A HA     1 
ATOM   1776 H HB     . ILE A 1 199 ? 116.678 100.448 103.843 1.00 62.97  ? 190 ILE A HB     1 
ATOM   1777 H HG12   . ILE A 1 199 ? 114.498 99.657  103.958 1.00 62.97  ? 190 ILE A HG12   1 
ATOM   1778 H HG13   . ILE A 1 199 ? 115.062 99.383  102.501 1.00 62.97  ? 190 ILE A HG13   1 
ATOM   1779 H HG21   . ILE A 1 199 ? 117.259 98.750  102.148 1.00 62.97  ? 190 ILE A HG21   1 
ATOM   1780 H HG22   . ILE A 1 199 ? 118.406 99.298  103.098 1.00 62.97  ? 190 ILE A HG22   1 
ATOM   1781 H HG23   . ILE A 1 199 ? 117.725 97.893  103.399 1.00 62.97  ? 190 ILE A HG23   1 
ATOM   1782 H HD11   . ILE A 1 199 ? 114.095 97.462  102.906 1.00 62.97  ? 190 ILE A HD11   1 
ATOM   1783 H HD12   . ILE A 1 199 ? 114.416 97.515  104.461 1.00 62.97  ? 190 ILE A HD12   1 
ATOM   1784 H HD13   . ILE A 1 199 ? 115.555 97.129  103.422 1.00 62.97  ? 190 ILE A HD13   1 
ATOM   1785 N N      . LEU A 1 200 ? 118.605 100.207 106.527 1.00 64.59  ? 191 LEU A N      1 
ATOM   1786 C CA     . LEU A 1 200 ? 119.886 100.121 107.219 1.00 64.59  ? 191 LEU A CA     1 
ATOM   1787 C C      . LEU A 1 200 ? 119.857 98.961  108.197 1.00 64.59  ? 191 LEU A C      1 
ATOM   1788 O O      . LEU A 1 200 ? 120.822 98.197  108.301 1.00 64.59  ? 191 LEU A O      1 
ATOM   1789 C CB     . LEU A 1 200 ? 120.209 101.432 107.941 1.00 64.59  ? 191 LEU A CB     1 
ATOM   1790 C CG     . LEU A 1 200 ? 120.946 102.520 107.151 1.00 64.59  ? 191 LEU A CG     1 
ATOM   1791 C CD1    . LEU A 1 200 ? 121.273 103.696 108.059 1.00 64.59  ? 191 LEU A CD1    1 
ATOM   1792 C CD2    . LEU A 1 200 ? 122.215 101.990 106.500 1.00 64.59  ? 191 LEU A CD2    1 
ATOM   1793 H H      . LEU A 1 200 ? 118.182 100.949 106.625 1.00 64.59  ? 191 LEU A H      1 
ATOM   1794 H HA     . LEU A 1 200 ? 120.583 99.943  106.570 1.00 64.59  ? 191 LEU A HA     1 
ATOM   1795 H HB2    . LEU A 1 200 ? 119.372 101.820 108.243 1.00 64.59  ? 191 LEU A HB2    1 
ATOM   1796 H HB3    . LEU A 1 200 ? 120.758 101.221 108.712 1.00 64.59  ? 191 LEU A HB3    1 
ATOM   1797 H HG     . LEU A 1 200 ? 120.364 102.843 106.446 1.00 64.59  ? 191 LEU A HG     1 
ATOM   1798 H HD11   . LEU A 1 200 ? 121.693 104.394 107.532 1.00 64.59  ? 191 LEU A HD11   1 
ATOM   1799 H HD12   . LEU A 1 200 ? 121.877 103.398 108.757 1.00 64.59  ? 191 LEU A HD12   1 
ATOM   1800 H HD13   . LEU A 1 200 ? 120.451 104.028 108.452 1.00 64.59  ? 191 LEU A HD13   1 
ATOM   1801 H HD21   . LEU A 1 200 ? 122.690 101.433 107.137 1.00 64.59  ? 191 LEU A HD21   1 
ATOM   1802 H HD22   . LEU A 1 200 ? 121.976 101.470 105.718 1.00 64.59  ? 191 LEU A HD22   1 
ATOM   1803 H HD23   . LEU A 1 200 ? 122.770 102.741 106.237 1.00 64.59  ? 191 LEU A HD23   1 
ATOM   1804 N N      . GLY A 1 201 ? 118.750 98.807  108.916 1.00 64.19  ? 192 GLY A N      1 
ATOM   1805 C CA     . GLY A 1 201 ? 118.438 97.503  109.469 1.00 64.19  ? 192 GLY A CA     1 
ATOM   1806 C C      . GLY A 1 201 ? 118.375 96.475  108.355 1.00 64.19  ? 192 GLY A C      1 
ATOM   1807 O O      . GLY A 1 201 ? 117.762 96.703  107.310 1.00 64.19  ? 192 GLY A O      1 
ATOM   1808 H H      . GLY A 1 201 ? 118.180 99.426  109.092 1.00 64.19  ? 192 GLY A H      1 
ATOM   1809 H HA2    . GLY A 1 201 ? 119.124 97.239  110.102 1.00 64.19  ? 192 GLY A HA2    1 
ATOM   1810 H HA3    . GLY A 1 201 ? 117.582 97.533  109.923 1.00 64.19  ? 192 GLY A HA3    1 
ATOM   1811 N N      . HIS A 1 202 ? 119.032 95.341  108.574 1.00 64.15  ? 193 HIS A N      1 
ATOM   1812 C CA     . HIS A 1 202 ? 119.307 94.326  107.558 1.00 64.15  ? 193 HIS A CA     1 
ATOM   1813 C C      . HIS A 1 202 ? 120.484 94.735  106.684 1.00 64.15  ? 193 HIS A C      1 
ATOM   1814 O O      . HIS A 1 202 ? 120.764 94.050  105.690 1.00 64.15  ? 193 HIS A O      1 
ATOM   1815 C CB     . HIS A 1 202 ? 118.107 94.035  106.651 1.00 64.15  ? 193 HIS A CB     1 
ATOM   1816 C CG     . HIS A 1 202 ? 116.826 93.831  107.391 1.00 64.15  ? 193 HIS A CG     1 
ATOM   1817 N ND1    . HIS A 1 202 ? 116.562 92.693  108.120 1.00 64.15  ? 193 HIS A ND1    1 
ATOM   1818 C CD2    . HIS A 1 202 ? 115.734 94.620  107.515 1.00 64.15  ? 193 HIS A CD2    1 
ATOM   1819 C CE1    . HIS A 1 202 ? 115.361 92.790  108.662 1.00 64.15  ? 193 HIS A CE1    1 
ATOM   1820 N NE2    . HIS A 1 202 ? 114.837 93.949  108.310 1.00 64.15  ? 193 HIS A NE2    1 
ATOM   1821 H H      . HIS A 1 202 ? 119.346 95.129  109.346 1.00 64.15  ? 193 HIS A H      1 
ATOM   1822 H HA     . HIS A 1 202 ? 119.544 93.497  108.004 1.00 64.15  ? 193 HIS A HA     1 
ATOM   1823 H HB2    . HIS A 1 202 ? 117.984 94.773  106.035 1.00 64.15  ? 193 HIS A HB2    1 
ATOM   1824 H HB3    . HIS A 1 202 ? 118.288 93.223  106.150 1.00 64.15  ? 193 HIS A HB3    1 
ATOM   1825 H HD1    . HIS A 1 202 ? 117.096 92.024  108.209 1.00 64.15  ? 193 HIS A HD1    1 
ATOM   1826 H HD2    . HIS A 1 202 ? 115.613 95.459  107.132 1.00 64.15  ? 193 HIS A HD2    1 
ATOM   1827 H HE1    . HIS A 1 202 ? 114.954 92.150  109.200 1.00 64.15  ? 193 HIS A HE1    1 
ATOM   1828 N N      . TYR A 1 203 ? 121.169 95.836  107.005 1.00 65.09  ? 194 TYR A N      1 
ATOM   1829 C CA     . TYR A 1 203 ? 122.406 96.187  106.319 1.00 65.09  ? 194 TYR A CA     1 
ATOM   1830 C C      . TYR A 1 203 ? 123.264 94.945  106.115 1.00 65.09  ? 194 TYR A C      1 
ATOM   1831 O O      . TYR A 1 203 ? 123.593 94.569  104.985 1.00 65.09  ? 194 TYR A O      1 
ATOM   1832 C CB     . TYR A 1 203 ? 123.153 97.251  107.132 1.00 65.09  ? 194 TYR A CB     1 
ATOM   1833 C CG     . TYR A 1 203 ? 124.651 97.262  106.947 1.00 65.09  ? 194 TYR A CG     1 
ATOM   1834 C CD1    . TYR A 1 203 ? 125.235 97.948  105.894 1.00 65.09  ? 194 TYR A CD1    1 
ATOM   1835 C CD2    . TYR A 1 203 ? 125.483 96.602  107.838 1.00 65.09  ? 194 TYR A CD2    1 
ATOM   1836 C CE1    . TYR A 1 203 ? 126.602 97.964  105.725 1.00 65.09  ? 194 TYR A CE1    1 
ATOM   1837 C CE2    . TYR A 1 203 ? 126.850 96.612  107.678 1.00 65.09  ? 194 TYR A CE2    1 
ATOM   1838 C CZ     . TYR A 1 203 ? 127.405 97.295  106.620 1.00 65.09  ? 194 TYR A CZ     1 
ATOM   1839 O OH     . TYR A 1 203 ? 128.770 97.310  106.456 1.00 65.09  ? 194 TYR A OH     1 
ATOM   1840 H H      . TYR A 1 203 ? 120.937 96.395  107.616 1.00 65.09  ? 194 TYR A H      1 
ATOM   1841 H HA     . TYR A 1 203 ? 122.197 96.559  105.448 1.00 65.09  ? 194 TYR A HA     1 
ATOM   1842 H HB2    . TYR A 1 203 ? 122.821 98.126  106.876 1.00 65.09  ? 194 TYR A HB2    1 
ATOM   1843 H HB3    . TYR A 1 203 ? 122.977 97.098  108.073 1.00 65.09  ? 194 TYR A HB3    1 
ATOM   1844 H HD1    . TYR A 1 203 ? 124.695 98.399  105.287 1.00 65.09  ? 194 TYR A HD1    1 
ATOM   1845 H HD2    . TYR A 1 203 ? 125.109 96.139  108.553 1.00 65.09  ? 194 TYR A HD2    1 
ATOM   1846 H HE1    . TYR A 1 203 ? 126.979 98.425  105.011 1.00 65.09  ? 194 TYR A HE1    1 
ATOM   1847 H HE2    . TYR A 1 203 ? 127.395 96.162  108.282 1.00 65.09  ? 194 TYR A HE2    1 
ATOM   1848 H HH     . TYR A 1 203 ? 129.136 96.852  107.058 1.00 65.09  ? 194 TYR A HH     1 
ATOM   1849 N N      . PHE A 1 204 ? 123.621 94.292  107.216 1.00 69.70  ? 195 PHE A N      1 
ATOM   1850 C CA     . PHE A 1 204 ? 124.216 92.966  107.172 1.00 69.70  ? 195 PHE A CA     1 
ATOM   1851 C C      . PHE A 1 204 ? 123.685 92.119  108.323 1.00 69.70  ? 195 PHE A C      1 
ATOM   1852 O O      . PHE A 1 204 ? 124.372 91.211  108.804 1.00 69.70  ? 195 PHE A O      1 
ATOM   1853 C CB     . PHE A 1 204 ? 125.750 93.054  107.216 1.00 69.70  ? 195 PHE A CB     1 
ATOM   1854 C CG     . PHE A 1 204 ? 126.467 91.983  106.418 1.00 69.70  ? 195 PHE A CG     1 
ATOM   1855 C CD1    . PHE A 1 204 ? 125.878 91.369  105.319 1.00 69.70  ? 195 PHE A CD1    1 
ATOM   1856 C CD2    . PHE A 1 204 ? 127.749 91.601  106.774 1.00 69.70  ? 195 PHE A CD2    1 
ATOM   1857 C CE1    . PHE A 1 204 ? 126.552 90.400  104.604 1.00 69.70  ? 195 PHE A CE1    1 
ATOM   1858 C CE2    . PHE A 1 204 ? 128.424 90.633  106.060 1.00 69.70  ? 195 PHE A CE2    1 
ATOM   1859 C CZ     . PHE A 1 204 ? 127.825 90.033  104.974 1.00 69.70  ? 195 PHE A CZ     1 
ATOM   1860 H H      . PHE A 1 204 ? 123.525 94.603  108.013 1.00 69.70  ? 195 PHE A H      1 
ATOM   1861 H HA     . PHE A 1 204 ? 123.927 92.548  106.351 1.00 69.70  ? 195 PHE A HA     1 
ATOM   1862 H HB2    . PHE A 1 204 ? 126.022 93.917  106.865 1.00 69.70  ? 195 PHE A HB2    1 
ATOM   1863 H HB3    . PHE A 1 204 ? 126.038 92.974  108.138 1.00 69.70  ? 195 PHE A HB3    1 
ATOM   1864 H HD1    . PHE A 1 204 ? 125.020 91.608  105.058 1.00 69.70  ? 195 PHE A HD1    1 
ATOM   1865 H HD2    . PHE A 1 204 ? 128.160 92.001  107.506 1.00 69.70  ? 195 PHE A HD2    1 
ATOM   1866 H HE1    . PHE A 1 204 ? 126.146 89.996  103.871 1.00 69.70  ? 195 PHE A HE1    1 
ATOM   1867 H HE2    . PHE A 1 204 ? 129.285 90.384  106.311 1.00 69.70  ? 195 PHE A HE2    1 
ATOM   1868 H HZ     . PHE A 1 204 ? 128.281 89.380  104.493 1.00 69.70  ? 195 PHE A HZ     1 
ATOM   1869 N N      . LYS A 1 205 ? 122.459 92.409  108.767 1.00 70.64  ? 196 LYS A N      1 
ATOM   1870 C CA     . LYS A 1 205 ? 121.849 91.804  109.947 1.00 70.64  ? 196 LYS A CA     1 
ATOM   1871 C C      . LYS A 1 205 ? 122.847 91.682  111.090 1.00 70.64  ? 196 LYS A C      1 
ATOM   1872 O O      . LYS A 1 205 ? 122.827 90.697  111.834 1.00 70.64  ? 196 LYS A O      1 
ATOM   1873 C CB     . LYS A 1 205 ? 121.245 90.434  109.614 1.00 70.64  ? 196 LYS A CB     1 
ATOM   1874 C CG     . LYS A 1 205 ? 122.144 89.484  108.843 1.00 70.64  ? 196 LYS A CG     1 
ATOM   1875 C CD     . LYS A 1 205 ? 121.416 88.197  108.513 1.00 70.64  ? 196 LYS A CD     1 
ATOM   1876 C CE     . LYS A 1 205 ? 122.239 87.320  107.593 1.00 70.64  ? 196 LYS A CE     1 
ATOM   1877 N NZ     . LYS A 1 205 ? 123.484 86.846  108.250 1.00 70.64  ? 196 LYS A NZ     1 
ATOM   1878 H H      . LYS A 1 205 ? 121.940 92.973  108.379 1.00 70.64  ? 196 LYS A H      1 
ATOM   1879 H HA     . LYS A 1 205 ? 121.124 92.377  110.251 1.00 70.64  ? 196 LYS A HA     1 
ATOM   1880 H HB2    . LYS A 1 205 ? 121.004 89.992  110.445 1.00 70.64  ? 196 LYS A HB2    1 
ATOM   1881 H HB3    . LYS A 1 205 ? 120.449 90.574  109.078 1.00 70.64  ? 196 LYS A HB3    1 
ATOM   1882 H HG2    . LYS A 1 205 ? 122.410 89.892  108.006 1.00 70.64  ? 196 LYS A HG2    1 
ATOM   1883 H HG3    . LYS A 1 205 ? 122.922 89.266  109.379 1.00 70.64  ? 196 LYS A HG3    1 
ATOM   1884 H HD2    . LYS A 1 205 ? 121.248 87.706  109.332 1.00 70.64  ? 196 LYS A HD2    1 
ATOM   1885 H HD3    . LYS A 1 205 ? 120.580 88.407  108.070 1.00 70.64  ? 196 LYS A HD3    1 
ATOM   1886 H HE2    . LYS A 1 205 ? 121.715 86.545  107.336 1.00 70.64  ? 196 LYS A HE2    1 
ATOM   1887 H HE3    . LYS A 1 205 ? 122.488 87.831  106.807 1.00 70.64  ? 196 LYS A HE3    1 
ATOM   1888 H HZ1    . LYS A 1 205 ? 123.986 87.541  108.489 1.00 70.64  ? 196 LYS A HZ1    1 
ATOM   1889 H HZ2    . LYS A 1 205 ? 123.947 86.333  107.690 1.00 70.64  ? 196 LYS A HZ2    1 
ATOM   1890 H HZ3    . LYS A 1 205 ? 123.283 86.372  108.976 1.00 70.64  ? 196 LYS A HZ3    1 
ATOM   1891 N N      . LYS A 1 206 ? 123.720 92.670  111.234 1.00 73.75  ? 197 LYS A N      1 
ATOM   1892 C CA     . LYS A 1 206 ? 124.650 92.755  112.357 1.00 73.75  ? 197 LYS A CA     1 
ATOM   1893 C C      . LYS A 1 206 ? 125.287 94.141  112.326 1.00 73.75  ? 197 LYS A C      1 
ATOM   1894 O O      . LYS A 1 206 ? 124.902 95.004  111.528 1.00 73.75  ? 197 LYS A O      1 
ATOM   1895 C CB     . LYS A 1 206 ? 125.698 91.642  112.308 1.00 73.75  ? 197 LYS A CB     1 
ATOM   1896 C CG     . LYS A 1 206 ? 126.644 91.713  111.116 1.00 73.75  ? 197 LYS A CG     1 
ATOM   1897 C CD     . LYS A 1 206 ? 127.956 90.990  111.387 1.00 73.75  ? 197 LYS A CD     1 
ATOM   1898 C CE     . LYS A 1 206 ? 127.749 89.508  111.668 1.00 73.75  ? 197 LYS A CE     1 
ATOM   1899 N NZ     . LYS A 1 206 ? 129.039 88.797  111.896 1.00 73.75  ? 197 LYS A NZ     1 
ATOM   1900 H H      . LYS A 1 206 ? 123.795 93.326  110.682 1.00 73.75  ? 197 LYS A H      1 
ATOM   1901 H HA     . LYS A 1 206 ? 124.157 92.667  113.185 1.00 73.75  ? 197 LYS A HA     1 
ATOM   1902 H HB2    . LYS A 1 206 ? 126.236 91.689  113.115 1.00 73.75  ? 197 LYS A HB2    1 
ATOM   1903 H HB3    . LYS A 1 206 ? 125.239 90.787  112.267 1.00 73.75  ? 197 LYS A HB3    1 
ATOM   1904 H HG2    . LYS A 1 206 ? 126.221 91.294  110.350 1.00 73.75  ? 197 LYS A HG2    1 
ATOM   1905 H HG3    . LYS A 1 206 ? 126.853 92.638  110.917 1.00 73.75  ? 197 LYS A HG3    1 
ATOM   1906 H HD2    . LYS A 1 206 ? 128.531 91.072  110.610 1.00 73.75  ? 197 LYS A HD2    1 
ATOM   1907 H HD3    . LYS A 1 206 ? 128.383 91.388  112.162 1.00 73.75  ? 197 LYS A HD3    1 
ATOM   1908 H HE2    . LYS A 1 206 ? 127.206 89.408  112.465 1.00 73.75  ? 197 LYS A HE2    1 
ATOM   1909 H HE3    . LYS A 1 206 ? 127.309 89.096  110.908 1.00 73.75  ? 197 LYS A HE3    1 
ATOM   1910 H HZ1    . LYS A 1 206 ? 128.890 87.931  112.038 1.00 73.75  ? 197 LYS A HZ1    1 
ATOM   1911 H HZ2    . LYS A 1 206 ? 129.565 88.885  111.184 1.00 73.75  ? 197 LYS A HZ2    1 
ATOM   1912 H HZ3    . LYS A 1 206 ? 129.454 89.138  112.605 1.00 73.75  ? 197 LYS A HZ3    1 
ATOM   1913 N N      . ARG A 1 207 ? 126.253 94.359  113.217 1.00 73.93  ? 198 ARG A N      1 
ATOM   1914 C CA     . ARG A 1 207 ? 127.115 95.542  113.183 1.00 73.93  ? 198 ARG A CA     1 
ATOM   1915 C C      . ARG A 1 207 ? 126.311 96.836  113.071 1.00 73.93  ? 198 ARG A C      1 
ATOM   1916 O O      . ARG A 1 207 ? 126.762 97.815  112.474 1.00 73.93  ? 198 ARG A O      1 
ATOM   1917 C CB     . ARG A 1 207 ? 128.129 95.441  112.042 1.00 73.93  ? 198 ARG A CB     1 
ATOM   1918 C CG     . ARG A 1 207 ? 129.290 96.406  112.170 1.00 73.93  ? 198 ARG A CG     1 
ATOM   1919 C CD     . ARG A 1 207 ? 130.342 96.169  111.111 1.00 73.93  ? 198 ARG A CD     1 
ATOM   1920 N NE     . ARG A 1 207 ? 131.407 97.160  111.193 1.00 73.93  ? 198 ARG A NE     1 
ATOM   1921 C CZ     . ARG A 1 207 ? 132.491 97.164  110.429 1.00 73.93  ? 198 ARG A CZ     1 
ATOM   1922 N NH1    . ARG A 1 207 ? 132.694 96.234  109.511 1.00 73.93  ? 198 ARG A NH1    1 
ATOM   1923 N NH2    . ARG A 1 207 ? 133.394 98.126  110.592 1.00 73.93  ? 198 ARG A NH2    1 
ATOM   1924 H H      . ARG A 1 207 ? 126.425 93.826  113.869 1.00 73.93  ? 198 ARG A H      1 
ATOM   1925 H HA     . ARG A 1 207 ? 127.612 95.581  114.015 1.00 73.93  ? 198 ARG A HA     1 
ATOM   1926 H HB2    . ARG A 1 207 ? 128.489 94.541  112.029 1.00 73.93  ? 198 ARG A HB2    1 
ATOM   1927 H HB3    . ARG A 1 207 ? 127.674 95.623  111.205 1.00 73.93  ? 198 ARG A HB3    1 
ATOM   1928 H HG2    . ARG A 1 207 ? 128.970 97.316  112.078 1.00 73.93  ? 198 ARG A HG2    1 
ATOM   1929 H HG3    . ARG A 1 207 ? 129.705 96.281  113.036 1.00 73.93  ? 198 ARG A HG3    1 
ATOM   1930 H HD2    . ARG A 1 207 ? 130.732 95.290  111.239 1.00 73.93  ? 198 ARG A HD2    1 
ATOM   1931 H HD3    . ARG A 1 207 ? 129.933 96.232  110.233 1.00 73.93  ? 198 ARG A HD3    1 
ATOM   1932 H HE     . ARG A 1 207 ? 131.262 97.856  111.678 1.00 73.93  ? 198 ARG A HE     1 
ATOM   1933 H HH11   . ARG A 1 207 ? 132.118 95.607  109.396 1.00 73.93  ? 198 ARG A HH11   1 
ATOM   1934 H HH12   . ARG A 1 207 ? 133.405 96.256  109.027 1.00 73.93  ? 198 ARG A HH12   1 
ATOM   1935 H HH21   . ARG A 1 207 ? 133.270 98.735  111.187 1.00 73.93  ? 198 ARG A HH21   1 
ATOM   1936 H HH22   . ARG A 1 207 ? 134.101 98.139  110.103 1.00 73.93  ? 198 ARG A HH22   1 
ATOM   1937 N N      . LEU A 1 208 ? 125.112 96.857  113.641 1.00 72.03  ? 199 LEU A N      1 
ATOM   1938 C CA     . LEU A 1 208 ? 124.392 98.113  113.762 1.00 72.03  ? 199 LEU A CA     1 
ATOM   1939 C C      . LEU A 1 208 ? 125.112 99.027  114.747 1.00 72.03  ? 199 LEU A C      1 
ATOM   1940 O O      . LEU A 1 208 ? 125.849 98.579  115.630 1.00 72.03  ? 199 LEU A O      1 
ATOM   1941 C CB     . LEU A 1 208 ? 122.952 97.874  114.218 1.00 72.03  ? 199 LEU A CB     1 
ATOM   1942 C CG     . LEU A 1 208 ? 121.966 97.433  113.136 1.00 72.03  ? 199 LEU A CG     1 
ATOM   1943 C CD1    . LEU A 1 208 ? 120.620 97.087  113.749 1.00 72.03  ? 199 LEU A CD1    1 
ATOM   1944 C CD2    . LEU A 1 208 ? 121.806 98.520  112.088 1.00 72.03  ? 199 LEU A CD2    1 
ATOM   1945 H H      . LEU A 1 208 ? 124.700 96.172  113.959 1.00 72.03  ? 199 LEU A H      1 
ATOM   1946 H HA     . LEU A 1 208 ? 124.376 98.555  112.900 1.00 72.03  ? 199 LEU A HA     1 
ATOM   1947 H HB2    . LEU A 1 208 ? 122.959 97.185  114.901 1.00 72.03  ? 199 LEU A HB2    1 
ATOM   1948 H HB3    . LEU A 1 208 ? 122.613 98.699  114.598 1.00 72.03  ? 199 LEU A HB3    1 
ATOM   1949 H HG     . LEU A 1 208 ? 122.310 96.640  112.697 1.00 72.03  ? 199 LEU A HG     1 
ATOM   1950 H HD11   . LEU A 1 208 ? 120.011 96.822  113.042 1.00 72.03  ? 199 LEU A HD11   1 
ATOM   1951 H HD12   . LEU A 1 208 ? 120.737 96.356  114.376 1.00 72.03  ? 199 LEU A HD12   1 
ATOM   1952 H HD13   . LEU A 1 208 ? 120.273 97.866  114.210 1.00 72.03  ? 199 LEU A HD13   1 
ATOM   1953 H HD21   . LEU A 1 208 ? 121.032 98.318  111.540 1.00 72.03  ? 199 LEU A HD21   1 
ATOM   1954 H HD22   . LEU A 1 208 ? 121.682 99.372  112.535 1.00 72.03  ? 199 LEU A HD22   1 
ATOM   1955 H HD23   . LEU A 1 208 ? 122.604 98.549  111.537 1.00 72.03  ? 199 LEU A HD23   1 
ATOM   1956 N N      . GLY A 1 209 ? 124.892 100.328 114.586 1.00 74.40  ? 200 GLY A N      1 
ATOM   1957 C CA     . GLY A 1 209 ? 125.578 101.309 115.402 1.00 74.40  ? 200 GLY A CA     1 
ATOM   1958 C C      . GLY A 1 209 ? 126.845 101.809 114.741 1.00 74.40  ? 200 GLY A C      1 
ATOM   1959 O O      . GLY A 1 209 ? 127.021 103.015 114.566 1.00 74.40  ? 200 GLY A O      1 
ATOM   1960 H H      . GLY A 1 209 ? 124.348 100.664 114.010 1.00 74.40  ? 200 GLY A H      1 
ATOM   1961 H HA2    . GLY A 1 209 ? 124.992 102.068 115.554 1.00 74.40  ? 200 GLY A HA2    1 
ATOM   1962 H HA3    . GLY A 1 209 ? 125.810 100.920 116.259 1.00 74.40  ? 200 GLY A HA3    1 
ATOM   1963 N N      . LEU A 1 210 ? 127.741 100.894 114.366 1.00 73.37  ? 201 LEU A N      1 
ATOM   1964 C CA     . LEU A 1 210 ? 128.919 101.298 113.605 1.00 73.37  ? 201 LEU A CA     1 
ATOM   1965 C C      . LEU A 1 210 ? 128.519 101.852 112.244 1.00 73.37  ? 201 LEU A C      1 
ATOM   1966 O O      . LEU A 1 210 ? 129.072 102.858 111.783 1.00 73.37  ? 201 LEU A O      1 
ATOM   1967 C CB     . LEU A 1 210 ? 129.873 100.114 113.455 1.00 73.37  ? 201 LEU A CB     1 
ATOM   1968 C CG     . LEU A 1 210 ? 130.383 99.525  114.774 1.00 73.37  ? 201 LEU A CG     1 
ATOM   1969 C CD1    . LEU A 1 210 ? 131.229 98.288  114.524 1.00 73.37  ? 201 LEU A CD1    1 
ATOM   1970 C CD2    . LEU A 1 210 ? 131.170 100.561 115.569 1.00 73.37  ? 201 LEU A CD2    1 
ATOM   1971 H H      . LEU A 1 210 ? 127.692 100.053 114.537 1.00 73.37  ? 201 LEU A H      1 
ATOM   1972 H HA     . LEU A 1 210 ? 129.381 102.002 114.087 1.00 73.37  ? 201 LEU A HA     1 
ATOM   1973 H HB2    . LEU A 1 210 ? 129.412 99.406  112.978 1.00 73.37  ? 201 LEU A HB2    1 
ATOM   1974 H HB3    . LEU A 1 210 ? 130.645 100.400 112.943 1.00 73.37  ? 201 LEU A HB3    1 
ATOM   1975 H HG     . LEU A 1 210 ? 129.621 99.257  115.311 1.00 73.37  ? 201 LEU A HG     1 
ATOM   1976 H HD11   . LEU A 1 210 ? 131.885 98.207  115.233 1.00 73.37  ? 201 LEU A HD11   1 
ATOM   1977 H HD12   . LEU A 1 210 ? 130.654 97.509  114.520 1.00 73.37  ? 201 LEU A HD12   1 
ATOM   1978 H HD13   . LEU A 1 210 ? 131.678 98.379  113.669 1.00 73.37  ? 201 LEU A HD13   1 
ATOM   1979 H HD21   . LEU A 1 210 ? 131.547 100.136 116.356 1.00 73.37  ? 201 LEU A HD21   1 
ATOM   1980 H HD22   . LEU A 1 210 ? 131.881 100.913 115.011 1.00 73.37  ? 201 LEU A HD22   1 
ATOM   1981 H HD23   . LEU A 1 210 ? 130.573 101.277 115.836 1.00 73.37  ? 201 LEU A HD23   1 
ATOM   1982 N N      . VAL A 1 211 ? 127.546 101.216 111.591 1.00 71.28  ? 202 VAL A N      1 
ATOM   1983 C CA     . VAL A 1 211 ? 127.030 101.745 110.333 1.00 71.28  ? 202 VAL A CA     1 
ATOM   1984 C C      . VAL A 1 211 ? 126.399 103.112 110.556 1.00 71.28  ? 202 VAL A C      1 
ATOM   1985 O O      . VAL A 1 211 ? 126.547 104.022 109.732 1.00 71.28  ? 202 VAL A O      1 
ATOM   1986 C CB     . VAL A 1 211 ? 126.027 100.757 109.706 1.00 71.28  ? 202 VAL A CB     1 
ATOM   1987 C CG1    . VAL A 1 211 ? 125.380 101.371 108.472 1.00 71.28  ? 202 VAL A CG1    1 
ATOM   1988 C CG2    . VAL A 1 211 ? 126.717 99.441  109.362 1.00 71.28  ? 202 VAL A CG2    1 
ATOM   1989 H H      . VAL A 1 211 ? 127.173 100.486 111.853 1.00 71.28  ? 202 VAL A H      1 
ATOM   1990 H HA     . VAL A 1 211 ? 127.766 101.855 109.712 1.00 71.28  ? 202 VAL A HA     1 
ATOM   1991 H HB     . VAL A 1 211 ? 125.327 100.569 110.350 1.00 71.28  ? 202 VAL A HB     1 
ATOM   1992 H HG11   . VAL A 1 211 ? 125.986 102.024 108.089 1.00 71.28  ? 202 VAL A HG11   1 
ATOM   1993 H HG12   . VAL A 1 211 ? 125.195 100.672 107.826 1.00 71.28  ? 202 VAL A HG12   1 
ATOM   1994 H HG13   . VAL A 1 211 ? 124.550 101.800 108.734 1.00 71.28  ? 202 VAL A HG13   1 
ATOM   1995 H HG21   . VAL A 1 211 ? 127.576 99.403  109.812 1.00 71.28  ? 202 VAL A HG21   1 
ATOM   1996 H HG22   . VAL A 1 211 ? 126.157 98.707  109.659 1.00 71.28  ? 202 VAL A HG22   1 
ATOM   1997 H HG23   . VAL A 1 211 ? 126.847 99.389  108.403 1.00 71.28  ? 202 VAL A HG23   1 
ATOM   1998 N N      . ASN A 1 212 ? 125.671 103.275 111.662 1.00 72.29  ? 203 ASN A N      1 
ATOM   1999 C CA     . ASN A 1 212 ? 125.061 104.568 111.953 1.00 72.29  ? 203 ASN A CA     1 
ATOM   2000 C C      . ASN A 1 212 ? 126.122 105.640 112.159 1.00 72.29  ? 203 ASN A C      1 
ATOM   2001 O O      . ASN A 1 212 ? 125.971 106.773 111.691 1.00 72.29  ? 203 ASN A O      1 
ATOM   2002 C CB     . ASN A 1 212 ? 124.161 104.456 113.182 1.00 72.29  ? 203 ASN A CB     1 
ATOM   2003 C CG     . ASN A 1 212 ? 122.934 103.610 112.925 1.00 72.29  ? 203 ASN A CG     1 
ATOM   2004 O OD1    . ASN A 1 212 ? 122.972 102.385 113.049 1.00 72.29  ? 203 ASN A OD1    1 
ATOM   2005 N ND2    . ASN A 1 212 ? 121.835 104.259 112.561 1.00 72.29  ? 203 ASN A ND2    1 
ATOM   2006 H H      . ASN A 1 212 ? 125.518 102.664 112.248 1.00 72.29  ? 203 ASN A H      1 
ATOM   2007 H HA     . ASN A 1 212 ? 124.509 104.833 111.201 1.00 72.29  ? 203 ASN A HA     1 
ATOM   2008 H HB2    . ASN A 1 212 ? 124.662 104.049 113.906 1.00 72.29  ? 203 ASN A HB2    1 
ATOM   2009 H HB3    . ASN A 1 212 ? 123.865 105.343 113.439 1.00 72.29  ? 203 ASN A HB3    1 
ATOM   2010 H HD21   . ASN A 1 212 ? 121.846 105.116 112.484 1.00 72.29  ? 203 ASN A HD21   1 
ATOM   2011 H HD22   . ASN A 1 212 ? 121.110 103.823 112.403 1.00 72.29  ? 203 ASN A HD22   1 
ATOM   2012 N N      . GLY A 1 213 ? 127.200 105.302 112.864 1.00 70.74  ? 204 GLY A N      1 
ATOM   2013 C CA     . GLY A 1 213 ? 128.290 106.248 113.026 1.00 70.74  ? 204 GLY A CA     1 
ATOM   2014 C C      . GLY A 1 213 ? 128.940 106.606 111.704 1.00 70.74  ? 204 GLY A C      1 
ATOM   2015 O O      . GLY A 1 213 ? 129.294 107.764 111.467 1.00 70.74  ? 204 GLY A O      1 
ATOM   2016 H H      . GLY A 1 213 ? 127.319 104.544 113.251 1.00 70.74  ? 204 GLY A H      1 
ATOM   2017 H HA2    . GLY A 1 213 ? 127.955 107.062 113.434 1.00 70.74  ? 204 GLY A HA2    1 
ATOM   2018 H HA3    . GLY A 1 213 ? 128.966 105.867 113.608 1.00 70.74  ? 204 GLY A HA3    1 
ATOM   2019 N N      . ILE A 1 214 ? 129.104 105.617 110.824 1.00 70.64  ? 205 ILE A N      1 
ATOM   2020 C CA     . ILE A 1 214 ? 129.650 105.886 109.496 1.00 70.64  ? 205 ILE A CA     1 
ATOM   2021 C C      . ILE A 1 214 ? 128.741 106.842 108.734 1.00 70.64  ? 205 ILE A C      1 
ATOM   2022 O O      . ILE A 1 214 ? 129.208 107.784 108.082 1.00 70.64  ? 205 ILE A O      1 
ATOM   2023 C CB     . ILE A 1 214 ? 129.852 104.566 108.730 1.00 70.64  ? 205 ILE A CB     1 
ATOM   2024 C CG1    . ILE A 1 214 ? 130.906 103.701 109.426 1.00 70.64  ? 205 ILE A CG1    1 
ATOM   2025 C CG2    . ILE A 1 214 ? 130.260 104.846 107.293 1.00 70.64  ? 205 ILE A CG2    1 
ATOM   2026 C CD1    . ILE A 1 214 ? 130.858 102.239 109.032 1.00 70.64  ? 205 ILE A CD1    1 
ATOM   2027 H H      . ILE A 1 214 ? 128.909 104.792 110.970 1.00 70.64  ? 205 ILE A H      1 
ATOM   2028 H HA     . ILE A 1 214 ? 130.517 106.311 109.593 1.00 70.64  ? 205 ILE A HA     1 
ATOM   2029 H HB     . ILE A 1 214 ? 129.011 104.081 108.723 1.00 70.64  ? 205 ILE A HB     1 
ATOM   2030 H HG12   . ILE A 1 214 ? 131.785 104.038 109.195 1.00 70.64  ? 205 ILE A HG12   1 
ATOM   2031 H HG13   . ILE A 1 214 ? 130.779 103.755 110.385 1.00 70.64  ? 205 ILE A HG13   1 
ATOM   2032 H HG21   . ILE A 1 214 ? 130.626 104.036 106.905 1.00 70.64  ? 205 ILE A HG21   1 
ATOM   2033 H HG22   . ILE A 1 214 ? 129.480 105.128 106.790 1.00 70.64  ? 205 ILE A HG22   1 
ATOM   2034 H HG23   . ILE A 1 214 ? 130.931 105.546 107.287 1.00 70.64  ? 205 ILE A HG23   1 
ATOM   2035 H HD11   . ILE A 1 214 ? 131.524 101.753 109.544 1.00 70.64  ? 205 ILE A HD11   1 
ATOM   2036 H HD12   . ILE A 1 214 ? 129.974 101.889 109.224 1.00 70.64  ? 205 ILE A HD12   1 
ATOM   2037 H HD13   . ILE A 1 214 ? 131.047 102.159 108.085 1.00 70.64  ? 205 ILE A HD13   1 
ATOM   2038 N N      . VAL A 1 215 ? 127.430 106.610 108.799 1.00 68.23  ? 206 VAL A N      1 
ATOM   2039 C CA     . VAL A 1 215 ? 126.482 107.468 108.092 1.00 68.23  ? 206 VAL A CA     1 
ATOM   2040 C C      . VAL A 1 215 ? 126.513 108.880 108.660 1.00 68.23  ? 206 VAL A C      1 
ATOM   2041 O O      . VAL A 1 215 ? 126.406 109.866 107.921 1.00 68.23  ? 206 VAL A O      1 
ATOM   2042 C CB     . VAL A 1 215 ? 125.068 106.864 108.158 1.00 68.23  ? 206 VAL A CB     1 
ATOM   2043 C CG1    . VAL A 1 215 ? 124.036 107.873 107.686 1.00 68.23  ? 206 VAL A CG1    1 
ATOM   2044 C CG2    . VAL A 1 215 ? 124.997 105.595 107.325 1.00 68.23  ? 206 VAL A CG2    1 
ATOM   2045 H H      . VAL A 1 215 ? 127.067 105.968 109.241 1.00 68.23  ? 206 VAL A H      1 
ATOM   2046 H HA     . VAL A 1 215 ? 126.740 107.518 107.158 1.00 68.23  ? 206 VAL A HA     1 
ATOM   2047 H HB     . VAL A 1 215 ? 124.864 106.632 109.078 1.00 68.23  ? 206 VAL A HB     1 
ATOM   2048 H HG11   . VAL A 1 215 ? 123.853 108.501 108.403 1.00 68.23  ? 206 VAL A HG11   1 
ATOM   2049 H HG12   . VAL A 1 215 ? 123.223 107.400 107.447 1.00 68.23  ? 206 VAL A HG12   1 
ATOM   2050 H HG13   . VAL A 1 215 ? 124.384 108.341 106.912 1.00 68.23  ? 206 VAL A HG13   1 
ATOM   2051 H HG21   . VAL A 1 215 ? 125.163 105.817 106.396 1.00 68.23  ? 206 VAL A HG21   1 
ATOM   2052 H HG22   . VAL A 1 215 ? 124.113 105.205 107.419 1.00 68.23  ? 206 VAL A HG22   1 
ATOM   2053 H HG23   . VAL A 1 215 ? 125.668 104.970 107.641 1.00 68.23  ? 206 VAL A HG23   1 
ATOM   2054 N N      . THR A 1 216 ? 126.628 109.001 109.983 1.00 69.96  ? 207 THR A N      1 
ATOM   2055 C CA     . THR A 1 216 ? 126.721 110.322 110.594 1.00 69.96  ? 207 THR A CA     1 
ATOM   2056 C C      . THR A 1 216 ? 127.992 111.039 110.158 1.00 69.96  ? 207 THR A C      1 
ATOM   2057 O O      . THR A 1 216 ? 127.961 112.237 109.854 1.00 69.96  ? 207 THR A O      1 
ATOM   2058 C CB     . THR A 1 216 ? 126.666 110.202 112.117 1.00 69.96  ? 207 THR A CB     1 
ATOM   2059 O OG1    . THR A 1 216 ? 125.376 109.718 112.512 1.00 69.96  ? 207 THR A OG1    1 
ATOM   2060 C CG2    . THR A 1 216 ? 126.925 111.553 112.774 1.00 69.96  ? 207 THR A CG2    1 
ATOM   2061 H H      . THR A 1 216 ? 126.655 108.344 110.538 1.00 69.96  ? 207 THR A H      1 
ATOM   2062 H HA     . THR A 1 216 ? 125.962 110.855 110.308 1.00 69.96  ? 207 THR A HA     1 
ATOM   2063 H HB     . THR A 1 216 ? 127.348 109.580 112.416 1.00 69.96  ? 207 THR A HB     1 
ATOM   2064 H HG1    . THR A 1 216 ? 125.239 108.960 112.179 1.00 69.96  ? 207 THR A HG1    1 
ATOM   2065 H HG21   . THR A 1 216 ? 127.871 111.762 112.749 1.00 69.96  ? 207 THR A HG21   1 
ATOM   2066 H HG22   . THR A 1 216 ? 126.633 111.530 113.699 1.00 69.96  ? 207 THR A HG22   1 
ATOM   2067 H HG23   . THR A 1 216 ? 126.433 112.247 112.308 1.00 69.96  ? 207 THR A HG23   1 
ATOM   2068 N N      . ALA A 1 217 ? 129.117 110.322 110.114 1.00 70.22  ? 208 ALA A N      1 
ATOM   2069 C CA     . ALA A 1 217 ? 130.356 110.927 109.637 1.00 70.22  ? 208 ALA A CA     1 
ATOM   2070 C C      . ALA A 1 217 ? 130.235 111.362 108.183 1.00 70.22  ? 208 ALA A C      1 
ATOM   2071 O O      . ALA A 1 217 ? 130.797 112.392 107.793 1.00 70.22  ? 208 ALA A O      1 
ATOM   2072 C CB     . ALA A 1 217 ? 131.518 109.949 109.799 1.00 70.22  ? 208 ALA A CB     1 
ATOM   2073 H H      . ALA A 1 217 ? 129.187 109.499 110.352 1.00 70.22  ? 208 ALA A H      1 
ATOM   2074 H HA     . ALA A 1 217 ? 130.548 111.715 110.170 1.00 70.22  ? 208 ALA A HA     1 
ATOM   2075 H HB1    . ALA A 1 217 ? 132.328 110.365 109.465 1.00 70.22  ? 208 ALA A HB1    1 
ATOM   2076 H HB2    . ALA A 1 217 ? 131.620 109.733 110.738 1.00 70.22  ? 208 ALA A HB2    1 
ATOM   2077 H HB3    . ALA A 1 217 ? 131.326 109.145 109.293 1.00 70.22  ? 208 ALA A HB3    1 
ATOM   2078 N N      . GLY A 1 218 ? 129.526 110.588 107.366 1.00 68.12  ? 209 GLY A N      1 
ATOM   2079 C CA     . GLY A 1 218 ? 129.301 110.967 105.985 1.00 68.12  ? 209 GLY A CA     1 
ATOM   2080 C C      . GLY A 1 218 ? 128.450 112.214 105.842 1.00 68.12  ? 209 GLY A C      1 
ATOM   2081 O O      . GLY A 1 218 ? 128.830 113.155 105.139 1.00 68.12  ? 209 GLY A O      1 
ATOM   2082 H H      . GLY A 1 218 ? 129.168 109.839 107.591 1.00 68.12  ? 209 GLY A H      1 
ATOM   2083 H HA2    . GLY A 1 218 ? 130.155 111.130 105.554 1.00 68.12  ? 209 GLY A HA2    1 
ATOM   2084 H HA3    . GLY A 1 218 ? 128.861 110.239 105.522 1.00 68.12  ? 209 GLY A HA3    1 
ATOM   2085 N N      . SER A 1 219 ? 127.295 112.235 106.514 1.00 68.00  ? 210 SER A N      1 
ATOM   2086 C CA     . SER A 1 219 ? 126.409 113.393 106.439 1.00 68.00  ? 210 SER A CA     1 
ATOM   2087 C C      . SER A 1 219 ? 127.030 114.628 107.076 1.00 68.00  ? 210 SER A C      1 
ATOM   2088 O O      . SER A 1 219 ? 126.625 115.755 106.756 1.00 68.00  ? 210 SER A O      1 
ATOM   2089 C CB     . SER A 1 219 ? 125.073 113.075 107.108 1.00 68.00  ? 210 SER A CB     1 
ATOM   2090 O OG     . SER A 1 219 ? 125.254 112.751 108.473 1.00 68.00  ? 210 SER A OG     1 
ATOM   2091 H H      . SER A 1 219 ? 127.008 111.598 107.015 1.00 68.00  ? 210 SER A H      1 
ATOM   2092 H HA     . SER A 1 219 ? 126.236 113.594 105.507 1.00 68.00  ? 210 SER A HA     1 
ATOM   2093 H HB2    . SER A 1 219 ? 124.495 113.852 107.042 1.00 68.00  ? 210 SER A HB2    1 
ATOM   2094 H HB3    . SER A 1 219 ? 124.666 112.320 106.656 1.00 68.00  ? 210 SER A HB3    1 
ATOM   2095 H HG     . SER A 1 219 ? 124.515 112.563 108.824 1.00 68.00  ? 210 SER A HG     1 
ATOM   2096 N N      . SER A 1 220 ? 127.993 114.442 107.979 1.00 67.98  ? 211 SER A N      1 
ATOM   2097 C CA     . SER A 1 220 ? 128.770 115.572 108.461 1.00 67.98  ? 211 SER A CA     1 
ATOM   2098 C C      . SER A 1 220 ? 129.411 116.316 107.302 1.00 67.98  ? 211 SER A C      1 
ATOM   2099 O O      . SER A 1 220 ? 129.511 117.546 107.322 1.00 67.98  ? 211 SER A O      1 
ATOM   2100 C CB     . SER A 1 220 ? 129.837 115.091 109.443 1.00 67.98  ? 211 SER A CB     1 
ATOM   2101 O OG     . SER A 1 220 ? 130.833 116.079 109.638 1.00 67.98  ? 211 SER A OG     1 
ATOM   2102 H H      . SER A 1 220 ? 128.210 113.683 108.321 1.00 67.98  ? 211 SER A H      1 
ATOM   2103 H HA     . SER A 1 220 ? 128.183 116.187 108.929 1.00 67.98  ? 211 SER A HA     1 
ATOM   2104 H HB2    . SER A 1 220 ? 129.416 114.896 110.295 1.00 67.98  ? 211 SER A HB2    1 
ATOM   2105 H HB3    . SER A 1 220 ? 130.253 114.290 109.091 1.00 67.98  ? 211 SER A HB3    1 
ATOM   2106 H HG     . SER A 1 220 ? 131.432 115.786 110.148 1.00 67.98  ? 211 SER A HG     1 
ATOM   2107 N N      . VAL A 1 221 ? 129.840 115.586 106.272 1.00 65.01  ? 212 VAL A N      1 
ATOM   2108 C CA     . VAL A 1 221 ? 130.487 116.227 105.130 1.00 65.01  ? 212 VAL A CA     1 
ATOM   2109 C C      . VAL A 1 221 ? 129.521 117.186 104.445 1.00 65.01  ? 212 VAL A C      1 
ATOM   2110 O O      . VAL A 1 221 ? 129.878 118.321 104.112 1.00 65.01  ? 212 VAL A O      1 
ATOM   2111 C CB     . VAL A 1 221 ? 131.019 115.166 104.150 1.00 65.01  ? 212 VAL A CB     1 
ATOM   2112 C CG1    . VAL A 1 221 ? 131.709 115.828 102.968 1.00 65.01  ? 212 VAL A CG1    1 
ATOM   2113 C CG2    . VAL A 1 221 ? 131.971 114.220 104.859 1.00 65.01  ? 212 VAL A CG2    1 
ATOM   2114 H H      . VAL A 1 221 ? 129.768 114.732 106.210 1.00 65.01  ? 212 VAL A H      1 
ATOM   2115 H HA     . VAL A 1 221 ? 131.244 116.744 105.448 1.00 65.01  ? 212 VAL A HA     1 
ATOM   2116 H HB     . VAL A 1 221 ? 130.274 114.646 103.810 1.00 65.01  ? 212 VAL A HB     1 
ATOM   2117 H HG11   . VAL A 1 221 ? 131.041 116.247 102.403 1.00 65.01  ? 212 VAL A HG11   1 
ATOM   2118 H HG12   . VAL A 1 221 ? 132.189 115.152 102.464 1.00 65.01  ? 212 VAL A HG12   1 
ATOM   2119 H HG13   . VAL A 1 221 ? 132.330 116.496 103.298 1.00 65.01  ? 212 VAL A HG13   1 
ATOM   2120 H HG21   . VAL A 1 221 ? 132.374 113.629 104.204 1.00 65.01  ? 212 VAL A HG21   1 
ATOM   2121 H HG22   . VAL A 1 221 ? 132.659 114.740 105.303 1.00 65.01  ? 212 VAL A HG22   1 
ATOM   2122 H HG23   . VAL A 1 221 ? 131.476 113.700 105.512 1.00 65.01  ? 212 VAL A HG23   1 
ATOM   2123 N N      . PHE A 1 222 ? 128.282 116.745 104.221 1.00 63.79  ? 213 PHE A N      1 
ATOM   2124 C CA     . PHE A 1 222 ? 127.317 117.601 103.537 1.00 63.79  ? 213 PHE A CA     1 
ATOM   2125 C C      . PHE A 1 222 ? 126.862 118.753 104.418 1.00 63.79  ? 213 PHE A C      1 
ATOM   2126 O O      . PHE A 1 222 ? 126.606 119.851 103.912 1.00 63.79  ? 213 PHE A O      1 
ATOM   2127 C CB     . PHE A 1 222 ? 126.118 116.781 103.073 1.00 63.79  ? 213 PHE A CB     1 
ATOM   2128 C CG     . PHE A 1 222 ? 126.407 115.938 101.876 1.00 63.79  ? 213 PHE A CG     1 
ATOM   2129 C CD1    . PHE A 1 222 ? 126.302 116.467 100.605 1.00 63.79  ? 213 PHE A CD1    1 
ATOM   2130 C CD2    . PHE A 1 222 ? 126.802 114.622 102.021 1.00 63.79  ? 213 PHE A CD2    1 
ATOM   2131 C CE1    . PHE A 1 222 ? 126.577 115.696 99.499  1.00 63.79  ? 213 PHE A CE1    1 
ATOM   2132 C CE2    . PHE A 1 222 ? 127.078 113.844 100.918 1.00 63.79  ? 213 PHE A CE2    1 
ATOM   2133 C CZ     . PHE A 1 222 ? 126.966 114.381 99.655  1.00 63.79  ? 213 PHE A CZ     1 
ATOM   2134 H H      . PHE A 1 222 ? 127.982 115.972 104.450 1.00 63.79  ? 213 PHE A H      1 
ATOM   2135 H HA     . PHE A 1 222 ? 127.739 117.979 102.750 1.00 63.79  ? 213 PHE A HA     1 
ATOM   2136 H HB2    . PHE A 1 222 ? 125.842 116.191 103.793 1.00 63.79  ? 213 PHE A HB2    1 
ATOM   2137 H HB3    . PHE A 1 222 ? 125.394 117.384 102.845 1.00 63.79  ? 213 PHE A HB3    1 
ATOM   2138 H HD1    . PHE A 1 222 ? 126.041 117.353 100.495 1.00 63.79  ? 213 PHE A HD1    1 
ATOM   2139 H HD2    . PHE A 1 222 ? 126.879 114.256 102.873 1.00 63.79  ? 213 PHE A HD2    1 
ATOM   2140 H HE1    . PHE A 1 222 ? 126.501 116.060 98.646  1.00 63.79  ? 213 PHE A HE1    1 
ATOM   2141 H HE2    . PHE A 1 222 ? 127.340 112.958 101.027 1.00 63.79  ? 213 PHE A HE2    1 
ATOM   2142 H HZ     . PHE A 1 222 ? 127.152 113.858 98.910  1.00 63.79  ? 213 PHE A HZ     1 
ATOM   2143 N N      . THR A 1 223 ? 126.748 118.530 105.727 1.00 64.67  ? 214 THR A N      1 
ATOM   2144 C CA     . THR A 1 223 ? 126.420 119.639 106.617 1.00 64.67  ? 214 THR A CA     1 
ATOM   2145 C C      . THR A 1 223 ? 127.532 120.682 106.616 1.00 64.67  ? 214 THR A C      1 
ATOM   2146 O O      . THR A 1 223 ? 127.265 121.888 106.656 1.00 64.67  ? 214 THR A O      1 
ATOM   2147 C CB     . THR A 1 223 ? 126.170 119.125 108.033 1.00 64.67  ? 214 THR A CB     1 
ATOM   2148 O OG1    . THR A 1 223 ? 125.264 118.016 107.990 1.00 64.67  ? 214 THR A OG1    1 
ATOM   2149 C CG2    . THR A 1 223 ? 125.575 120.225 108.901 1.00 64.67  ? 214 THR A CG2    1 
ATOM   2150 H H      . THR A 1 223 ? 126.852 117.770 106.114 1.00 64.67  ? 214 THR A H      1 
ATOM   2151 H HA     . THR A 1 223 ? 125.607 120.066 106.304 1.00 64.67  ? 214 THR A HA     1 
ATOM   2152 H HB     . THR A 1 223 ? 127.010 118.842 108.428 1.00 64.67  ? 214 THR A HB     1 
ATOM   2153 H HG1    . THR A 1 223 ? 125.619 117.368 107.589 1.00 64.67  ? 214 THR A HG1    1 
ATOM   2154 H HG21   . THR A 1 223 ? 125.355 119.871 109.777 1.00 64.67  ? 214 THR A HG21   1 
ATOM   2155 H HG22   . THR A 1 223 ? 124.768 120.571 108.489 1.00 64.67  ? 214 THR A HG22   1 
ATOM   2156 H HG23   . THR A 1 223 ? 126.212 120.949 109.005 1.00 64.67  ? 214 THR A HG23   1 
ATOM   2157 N N      . ILE A 1 224 ? 128.788 120.232 106.575 1.00 65.95  ? 215 ILE A N      1 
ATOM   2158 C CA     . ILE A 1 224 ? 129.925 121.147 106.606 1.00 65.95  ? 215 ILE A CA     1 
ATOM   2159 C C      . ILE A 1 224 ? 130.041 121.909 105.291 1.00 65.95  ? 215 ILE A C      1 
ATOM   2160 O O      . ILE A 1 224 ? 130.252 123.127 105.277 1.00 65.95  ? 215 ILE A O      1 
ATOM   2161 C CB     . ILE A 1 224 ? 131.215 120.364 106.915 1.00 65.95  ? 215 ILE A CB     1 
ATOM   2162 C CG1    . ILE A 1 224 ? 131.172 119.803 108.336 1.00 65.95  ? 215 ILE A CG1    1 
ATOM   2163 C CG2    . ILE A 1 224 ? 132.452 121.238 106.741 1.00 65.95  ? 215 ILE A CG2    1 
ATOM   2164 C CD1    . ILE A 1 224 ? 132.183 118.706 108.579 1.00 65.95  ? 215 ILE A CD1    1 
ATOM   2165 H H      . ILE A 1 224 ? 129.005 119.401 106.529 1.00 65.95  ? 215 ILE A H      1 
ATOM   2166 H HA     . ILE A 1 224 ? 129.790 121.795 107.315 1.00 65.95  ? 215 ILE A HA     1 
ATOM   2167 H HB     . ILE A 1 224 ? 131.278 119.621 106.295 1.00 65.95  ? 215 ILE A HB     1 
ATOM   2168 H HG12   . ILE A 1 224 ? 131.360 120.521 108.960 1.00 65.95  ? 215 ILE A HG12   1 
ATOM   2169 H HG13   . ILE A 1 224 ? 130.290 119.442 108.511 1.00 65.95  ? 215 ILE A HG13   1 
ATOM   2170 H HG21   . ILE A 1 224 ? 133.236 120.719 106.979 1.00 65.95  ? 215 ILE A HG21   1 
ATOM   2171 H HG22   . ILE A 1 224 ? 132.525 121.527 105.818 1.00 65.95  ? 215 ILE A HG22   1 
ATOM   2172 H HG23   . ILE A 1 224 ? 132.379 122.003 107.328 1.00 65.95  ? 215 ILE A HG23   1 
ATOM   2173 H HD11   . ILE A 1 224 ? 132.034 118.328 109.460 1.00 65.95  ? 215 ILE A HD11   1 
ATOM   2174 H HD12   . ILE A 1 224 ? 132.071 118.021 107.903 1.00 65.95  ? 215 ILE A HD12   1 
ATOM   2175 H HD13   . ILE A 1 224 ? 133.076 119.080 108.525 1.00 65.95  ? 215 ILE A HD13   1 
ATOM   2176 N N      . LEU A 1 225 ? 129.910 121.205 104.168 1.00 63.77  ? 216 LEU A N      1 
ATOM   2177 C CA     . LEU A 1 225 ? 130.294 121.755 102.874 1.00 63.77  ? 216 LEU A CA     1 
ATOM   2178 C C      . LEU A 1 225 ? 129.185 122.562 102.211 1.00 63.77  ? 216 LEU A C      1 
ATOM   2179 O O      . LEU A 1 225 ? 129.467 123.578 101.568 1.00 63.77  ? 216 LEU A O      1 
ATOM   2180 C CB     . LEU A 1 225 ? 130.734 120.621 101.946 1.00 63.77  ? 216 LEU A CB     1 
ATOM   2181 C CG     . LEU A 1 225 ? 131.150 121.018 100.530 1.00 63.77  ? 216 LEU A CG     1 
ATOM   2182 C CD1    . LEU A 1 225 ? 132.325 120.174 100.077 1.00 63.77  ? 216 LEU A CD1    1 
ATOM   2183 C CD2    . LEU A 1 225 ? 129.991 120.869 99.557  1.00 63.77  ? 216 LEU A CD2    1 
ATOM   2184 H H      . LEU A 1 225 ? 129.600 120.404 104.131 1.00 63.77  ? 216 LEU A H      1 
ATOM   2185 H HA     . LEU A 1 225 ? 131.053 122.345 103.000 1.00 63.77  ? 216 LEU A HA     1 
ATOM   2186 H HB2    . LEU A 1 225 ? 131.492 120.173 102.353 1.00 63.77  ? 216 LEU A HB2    1 
ATOM   2187 H HB3    . LEU A 1 225 ? 129.999 119.994 101.864 1.00 63.77  ? 216 LEU A HB3    1 
ATOM   2188 H HG     . LEU A 1 225 ? 131.428 121.948 100.530 1.00 63.77  ? 216 LEU A HG     1 
ATOM   2189 H HD11   . LEU A 1 225 ? 133.076 120.333 100.670 1.00 63.77  ? 216 LEU A HD11   1 
ATOM   2190 H HD12   . LEU A 1 225 ? 132.561 120.425 99.170  1.00 63.77  ? 216 LEU A HD12   1 
ATOM   2191 H HD13   . LEU A 1 225 ? 132.072 119.238 100.106 1.00 63.77  ? 216 LEU A HD13   1 
ATOM   2192 H HD21   . LEU A 1 225 ? 129.644 119.965 99.615  1.00 63.77  ? 216 LEU A HD21   1 
ATOM   2193 H HD22   . LEU A 1 225 ? 130.313 121.041 98.658  1.00 63.77  ? 216 LEU A HD22   1 
ATOM   2194 H HD23   . LEU A 1 225 ? 129.297 121.506 99.785  1.00 63.77  ? 216 LEU A HD23   1 
ATOM   2195 N N      . LEU A 1 226 ? 127.931 122.140 102.353 1.00 62.36  ? 217 LEU A N      1 
ATOM   2196 C CA     . LEU A 1 226 ? 126.847 122.781 101.613 1.00 62.36  ? 217 LEU A CA     1 
ATOM   2197 C C      . LEU A 1 226 ? 126.773 124.286 101.832 1.00 62.36  ? 217 LEU A C      1 
ATOM   2198 O O      . LEU A 1 226 ? 126.569 125.012 100.845 1.00 62.36  ? 217 LEU A O      1 
ATOM   2199 C CB     . LEU A 1 226 ? 125.512 122.117 101.978 1.00 62.36  ? 217 LEU A CB     1 
ATOM   2200 C CG     . LEU A 1 226 ? 124.361 122.401 101.011 1.00 62.36  ? 217 LEU A CG     1 
ATOM   2201 C CD1    . LEU A 1 226 ? 123.436 121.201 100.925 1.00 62.36  ? 217 LEU A CD1    1 
ATOM   2202 C CD2    . LEU A 1 226 ? 123.584 123.635 101.431 1.00 62.36  ? 217 LEU A CD2    1 
ATOM   2203 H H      . LEU A 1 226 ? 127.684 121.493 102.863 1.00 62.36  ? 217 LEU A H      1 
ATOM   2204 H HA     . LEU A 1 226 ? 126.996 122.632 100.666 1.00 62.36  ? 217 LEU A HA     1 
ATOM   2205 H HB2    . LEU A 1 226 ? 125.641 121.156 102.000 1.00 62.36  ? 217 LEU A HB2    1 
ATOM   2206 H HB3    . LEU A 1 226 ? 125.237 122.427 102.854 1.00 62.36  ? 217 LEU A HB3    1 
ATOM   2207 H HG     . LEU A 1 226 ? 124.725 122.564 100.127 1.00 62.36  ? 217 LEU A HG     1 
ATOM   2208 H HD11   . LEU A 1 226 ? 123.930 120.448 100.565 1.00 62.36  ? 217 LEU A HD11   1 
ATOM   2209 H HD12   . LEU A 1 226 ? 122.693 121.419 100.341 1.00 62.36  ? 217 LEU A HD12   1 
ATOM   2210 H HD13   . LEU A 1 226 ? 123.110 120.990 101.814 1.00 62.36  ? 217 LEU A HD13   1 
ATOM   2211 H HD21   . LEU A 1 226 ? 122.824 123.745 100.839 1.00 62.36  ? 217 LEU A HD21   1 
ATOM   2212 H HD22   . LEU A 1 226 ? 123.276 123.516 102.343 1.00 62.36  ? 217 LEU A HD22   1 
ATOM   2213 H HD23   . LEU A 1 226 ? 124.160 124.412 101.375 1.00 62.36  ? 217 LEU A HD23   1 
ATOM   2214 N N      . PRO A 1 227 ? 126.922 124.818 103.047 1.00 63.91  ? 218 PRO A N      1 
ATOM   2215 C CA     . PRO A 1 227 ? 126.860 126.279 103.204 1.00 63.91  ? 218 PRO A CA     1 
ATOM   2216 C C      . PRO A 1 227 ? 127.872 127.019 102.352 1.00 63.91  ? 218 PRO A C      1 
ATOM   2217 O O      . PRO A 1 227 ? 127.598 128.147 101.925 1.00 63.91  ? 218 PRO A O      1 
ATOM   2218 C CB     . PRO A 1 227 ? 127.128 126.482 104.701 1.00 63.91  ? 218 PRO A CB     1 
ATOM   2219 C CG     . PRO A 1 227 ? 126.708 125.209 105.332 1.00 63.91  ? 218 PRO A CG     1 
ATOM   2220 C CD     . PRO A 1 227 ? 127.049 124.134 104.344 1.00 63.91  ? 218 PRO A CD     1 
ATOM   2221 H HA     . PRO A 1 227 ? 125.970 126.601 102.993 1.00 63.91  ? 218 PRO A HA     1 
ATOM   2222 H HB2    . PRO A 1 227 ? 128.073 126.643 104.845 1.00 63.91  ? 218 PRO A HB2    1 
ATOM   2223 H HB3    . PRO A 1 227 ? 126.596 127.222 105.032 1.00 63.91  ? 218 PRO A HB3    1 
ATOM   2224 H HG2    . PRO A 1 227 ? 127.199 125.079 106.159 1.00 63.91  ? 218 PRO A HG2    1 
ATOM   2225 H HG3    . PRO A 1 227 ? 125.753 125.228 105.500 1.00 63.91  ? 218 PRO A HG3    1 
ATOM   2226 H HD2    . PRO A 1 227 ? 127.959 123.828 104.478 1.00 63.91  ? 218 PRO A HD2    1 
ATOM   2227 H HD3    . PRO A 1 227 ? 126.415 123.404 104.410 1.00 63.91  ? 218 PRO A HD3    1 
ATOM   2228 N N      . LEU A 1 228 ? 129.038 126.427 102.095 1.00 65.67  ? 219 LEU A N      1 
ATOM   2229 C CA     . LEU A 1 228 ? 130.030 127.094 101.259 1.00 65.67  ? 219 LEU A CA     1 
ATOM   2230 C C      . LEU A 1 228 ? 129.568 127.159 99.809  1.00 65.67  ? 219 LEU A C      1 
ATOM   2231 O O      . LEU A 1 228 ? 129.668 128.207 99.160  1.00 65.67  ? 219 LEU A O      1 
ATOM   2232 C CB     . LEU A 1 228 ? 131.373 126.373 101.364 1.00 65.67  ? 219 LEU A CB     1 
ATOM   2233 C CG     . LEU A 1 228 ? 132.468 126.862 100.413 1.00 65.67  ? 219 LEU A CG     1 
ATOM   2234 C CD1    . LEU A 1 228 ? 132.651 128.369 100.516 1.00 65.67  ? 219 LEU A CD1    1 
ATOM   2235 C CD2    . LEU A 1 228 ? 133.774 126.143 100.703 1.00 65.67  ? 219 LEU A CD2    1 
ATOM   2236 H H      . LEU A 1 228 ? 129.273 125.653 102.386 1.00 65.67  ? 219 LEU A H      1 
ATOM   2237 H HA     . LEU A 1 228 ? 130.150 128.003 101.577 1.00 65.67  ? 219 LEU A HA     1 
ATOM   2238 H HB2    . LEU A 1 228 ? 131.706 126.474 102.269 1.00 65.67  ? 219 LEU A HB2    1 
ATOM   2239 H HB3    . LEU A 1 228 ? 131.228 125.432 101.177 1.00 65.67  ? 219 LEU A HB3    1 
ATOM   2240 H HG     . LEU A 1 228 ? 132.213 126.653 99.501  1.00 65.67  ? 219 LEU A HG     1 
ATOM   2241 H HD11   . LEU A 1 228 ? 133.435 128.626 100.007 1.00 65.67  ? 219 LEU A HD11   1 
ATOM   2242 H HD12   . LEU A 1 228 ? 131.865 128.810 100.157 1.00 65.67  ? 219 LEU A HD12   1 
ATOM   2243 H HD13   . LEU A 1 228 ? 132.769 128.608 101.448 1.00 65.67  ? 219 LEU A HD13   1 
ATOM   2244 H HD21   . LEU A 1 228 ? 134.457 126.469 100.096 1.00 65.67  ? 219 LEU A HD21   1 
ATOM   2245 H HD22   . LEU A 1 228 ? 134.034 126.321 101.621 1.00 65.67  ? 219 LEU A HD22   1 
ATOM   2246 H HD23   . LEU A 1 228 ? 133.645 125.190 100.575 1.00 65.67  ? 219 LEU A HD23   1 
ATOM   2247 N N      . LEU A 1 229 ? 129.056 126.047 99.282  1.00 63.90  ? 220 LEU A N      1 
ATOM   2248 C CA     . LEU A 1 229 ? 128.610 126.027 97.893  1.00 63.90  ? 220 LEU A CA     1 
ATOM   2249 C C      . LEU A 1 229 ? 127.481 127.023 97.667  1.00 63.90  ? 220 LEU A C      1 
ATOM   2250 O O      . LEU A 1 229 ? 127.514 127.816 96.719  1.00 63.90  ? 220 LEU A O      1 
ATOM   2251 C CB     . LEU A 1 229 ? 128.161 124.614 97.516  1.00 63.90  ? 220 LEU A CB     1 
ATOM   2252 C CG     . LEU A 1 229 ? 127.485 124.444 96.155  1.00 63.90  ? 220 LEU A CG     1 
ATOM   2253 C CD1    . LEU A 1 229 ? 128.449 124.791 95.037  1.00 63.90  ? 220 LEU A CD1    1 
ATOM   2254 C CD2    . LEU A 1 229 ? 126.964 123.027 96.000  1.00 63.90  ? 220 LEU A CD2    1 
ATOM   2255 H H      . LEU A 1 229 ? 128.956 125.304 99.702  1.00 63.90  ? 220 LEU A H      1 
ATOM   2256 H HA     . LEU A 1 229 ? 129.353 126.274 97.319  1.00 63.90  ? 220 LEU A HA     1 
ATOM   2257 H HB2    . LEU A 1 229 ? 128.941 124.037 97.523  1.00 63.90  ? 220 LEU A HB2    1 
ATOM   2258 H HB3    . LEU A 1 229 ? 127.531 124.307 98.186  1.00 63.90  ? 220 LEU A HB3    1 
ATOM   2259 H HG     . LEU A 1 229 ? 126.727 125.044 96.094  1.00 63.90  ? 220 LEU A HG     1 
ATOM   2260 H HD11   . LEU A 1 229 ? 128.008 124.646 94.185  1.00 63.90  ? 220 LEU A HD11   1 
ATOM   2261 H HD12   . LEU A 1 229 ? 128.710 125.721 95.122  1.00 63.90  ? 220 LEU A HD12   1 
ATOM   2262 H HD13   . LEU A 1 229 ? 129.230 124.219 95.107  1.00 63.90  ? 220 LEU A HD13   1 
ATOM   2263 H HD21   . LEU A 1 229 ? 126.533 122.942 95.135  1.00 63.90  ? 220 LEU A HD21   1 
ATOM   2264 H HD22   . LEU A 1 229 ? 127.709 122.409 96.060  1.00 63.90  ? 220 LEU A HD22   1 
ATOM   2265 H HD23   . LEU A 1 229 ? 126.325 122.845 96.707  1.00 63.90  ? 220 LEU A HD23   1 
ATOM   2266 N N      . LEU A 1 230 ? 126.472 126.998 98.538  1.00 62.33  ? 221 LEU A N      1 
ATOM   2267 C CA     . LEU A 1 230 ? 125.291 127.829 98.338  1.00 62.33  ? 221 LEU A CA     1 
ATOM   2268 C C      . LEU A 1 230 ? 125.638 129.311 98.409  1.00 62.33  ? 221 LEU A C      1 
ATOM   2269 O O      . LEU A 1 230 ? 125.089 130.123 97.655  1.00 62.33  ? 221 LEU A O      1 
ATOM   2270 C CB     . LEU A 1 230 ? 124.233 127.462 99.378  1.00 62.33  ? 221 LEU A CB     1 
ATOM   2271 C CG     . LEU A 1 230 ? 122.851 128.097 99.250  1.00 62.33  ? 221 LEU A CG     1 
ATOM   2272 C CD1    . LEU A 1 230 ? 122.231 127.801 97.896  1.00 62.33  ? 221 LEU A CD1    1 
ATOM   2273 C CD2    . LEU A 1 230 ? 121.967 127.581 100.367 1.00 62.33  ? 221 LEU A CD2    1 
ATOM   2274 H H      . LEU A 1 230 ? 126.447 126.512 99.247  1.00 62.33  ? 221 LEU A H      1 
ATOM   2275 H HA     . LEU A 1 230 ? 124.924 127.646 97.458  1.00 62.33  ? 221 LEU A HA     1 
ATOM   2276 H HB2    . LEU A 1 230 ? 124.105 126.500 99.343  1.00 62.33  ? 221 LEU A HB2    1 
ATOM   2277 H HB3    . LEU A 1 230 ? 124.573 127.701 100.254 1.00 62.33  ? 221 LEU A HB3    1 
ATOM   2278 H HG     . LEU A 1 230 ? 122.931 129.059 99.342  1.00 62.33  ? 221 LEU A HG     1 
ATOM   2279 H HD11   . LEU A 1 230 ? 121.303 128.085 97.903  1.00 62.33  ? 221 LEU A HD11   1 
ATOM   2280 H HD12   . LEU A 1 230 ? 122.282 126.847 97.727  1.00 62.33  ? 221 LEU A HD12   1 
ATOM   2281 H HD13   . LEU A 1 230 ? 122.721 128.284 97.212  1.00 62.33  ? 221 LEU A HD13   1 
ATOM   2282 H HD21   . LEU A 1 230 ? 121.099 128.010 100.315 1.00 62.33  ? 221 LEU A HD21   1 
ATOM   2283 H HD22   . LEU A 1 230 ? 122.388 127.784 101.217 1.00 62.33  ? 221 LEU A HD22   1 
ATOM   2284 H HD23   . LEU A 1 230 ? 121.869 126.621 100.267 1.00 62.33  ? 221 LEU A HD23   1 
ATOM   2285 N N      . ARG A 1 231 ? 126.546 129.682 99.313  1.00 64.99  ? 222 ARG A N      1 
ATOM   2286 C CA     . ARG A 1 231 ? 126.879 131.092 99.493  1.00 64.99  ? 222 ARG A CA     1 
ATOM   2287 C C      . ARG A 1 231 ? 127.494 131.682 98.231  1.00 64.99  ? 222 ARG A C      1 
ATOM   2288 O O      . ARG A 1 231 ? 127.194 132.823 97.862  1.00 64.99  ? 222 ARG A O      1 
ATOM   2289 C CB     . ARG A 1 231 ? 127.826 131.260 100.681 1.00 64.99  ? 222 ARG A CB     1 
ATOM   2290 C CG     . ARG A 1 231 ? 128.384 132.664 100.843 1.00 64.99  ? 222 ARG A CG     1 
ATOM   2291 C CD     . ARG A 1 231 ? 127.287 133.707 100.943 1.00 64.99  ? 222 ARG A CD     1 
ATOM   2292 N NE     . ARG A 1 231 ? 127.841 135.053 100.993 1.00 64.99  ? 222 ARG A NE     1 
ATOM   2293 C CZ     . ARG A 1 231 ? 128.259 135.729 99.932  1.00 64.99  ? 222 ARG A CZ     1 
ATOM   2294 N NH1    . ARG A 1 231 ? 128.210 135.207 98.717  1.00 64.99  ? 222 ARG A NH1    1 
ATOM   2295 N NH2    . ARG A 1 231 ? 128.742 136.958 100.094 1.00 64.99  ? 222 ARG A NH2    1 
ATOM   2296 H H      . ARG A 1 231 ? 126.979 129.144 99.826  1.00 64.99  ? 222 ARG A H      1 
ATOM   2297 H HA     . ARG A 1 231 ? 126.064 131.581 99.688  1.00 64.99  ? 222 ARG A HA     1 
ATOM   2298 H HB2    . ARG A 1 231 ? 127.346 131.040 101.495 1.00 64.99  ? 222 ARG A HB2    1 
ATOM   2299 H HB3    . ARG A 1 231 ? 128.578 130.655 100.572 1.00 64.99  ? 222 ARG A HB3    1 
ATOM   2300 H HG2    . ARG A 1 231 ? 128.905 132.700 101.660 1.00 64.99  ? 222 ARG A HG2    1 
ATOM   2301 H HG3    . ARG A 1 231 ? 128.945 132.884 100.083 1.00 64.99  ? 222 ARG A HG3    1 
ATOM   2302 H HD2    . ARG A 1 231 ? 126.704 133.651 100.170 1.00 64.99  ? 222 ARG A HD2    1 
ATOM   2303 H HD3    . ARG A 1 231 ? 126.779 133.559 101.756 1.00 64.99  ? 222 ARG A HD3    1 
ATOM   2304 H HE     . ARG A 1 231 ? 127.951 135.412 101.767 1.00 64.99  ? 222 ARG A HE     1 
ATOM   2305 H HH11   . ARG A 1 231 ? 127.900 134.414 98.600  1.00 64.99  ? 222 ARG A HH11   1 
ATOM   2306 H HH12   . ARG A 1 231 ? 128.487 135.663 98.042  1.00 64.99  ? 222 ARG A HH12   1 
ATOM   2307 H HH21   . ARG A 1 231 ? 128.779 137.307 100.879 1.00 64.99  ? 222 ARG A HH21   1 
ATOM   2308 H HH22   . ARG A 1 231 ? 129.017 137.405 99.412  1.00 64.99  ? 222 ARG A HH22   1 
ATOM   2309 N N      . VAL A 1 232 ? 128.374 130.932 97.567  1.00 64.02  ? 223 VAL A N      1 
ATOM   2310 C CA     . VAL A 1 232 ? 128.953 131.425 96.322  1.00 64.02  ? 223 VAL A CA     1 
ATOM   2311 C C      . VAL A 1 232 ? 127.965 131.279 95.174  1.00 64.02  ? 223 VAL A C      1 
ATOM   2312 O O      . VAL A 1 232 ? 127.961 132.095 94.246  1.00 64.02  ? 223 VAL A O      1 
ATOM   2313 C CB     . VAL A 1 232 ? 130.273 130.698 96.015  1.00 64.02  ? 223 VAL A CB     1 
ATOM   2314 C CG1    . VAL A 1 232 ? 130.040 129.202 95.838  1.00 64.02  ? 223 VAL A CG1    1 
ATOM   2315 C CG2    . VAL A 1 232 ? 130.926 131.288 94.776  1.00 64.02  ? 223 VAL A CG2    1 
ATOM   2316 H H      . VAL A 1 232 ? 128.647 130.155 97.812  1.00 64.02  ? 223 VAL A H      1 
ATOM   2317 H HA     . VAL A 1 232 ? 129.151 132.370 96.423  1.00 64.02  ? 223 VAL A HA     1 
ATOM   2318 H HB     . VAL A 1 232 ? 130.879 130.822 96.762  1.00 64.02  ? 223 VAL A HB     1 
ATOM   2319 H HG11   . VAL A 1 232 ? 130.884 128.779 95.616  1.00 64.02  ? 223 VAL A HG11   1 
ATOM   2320 H HG12   . VAL A 1 232 ? 129.698 128.835 96.667  1.00 64.02  ? 223 VAL A HG12   1 
ATOM   2321 H HG13   . VAL A 1 232 ? 129.403 129.056 95.120  1.00 64.02  ? 223 VAL A HG13   1 
ATOM   2322 H HG21   . VAL A 1 232 ? 130.407 131.044 93.994  1.00 64.02  ? 223 VAL A HG21   1 
ATOM   2323 H HG22   . VAL A 1 232 ? 131.826 130.934 94.700  1.00 64.02  ? 223 VAL A HG22   1 
ATOM   2324 H HG23   . VAL A 1 232 ? 130.959 132.253 94.866  1.00 64.02  ? 223 VAL A HG23   1 
ATOM   2325 N N      . LEU A 1 233 ? 127.116 130.253 95.214  1.00 63.67  ? 224 LEU A N      1 
ATOM   2326 C CA     . LEU A 1 233 ? 126.155 130.015 94.147  1.00 63.67  ? 224 LEU A CA     1 
ATOM   2327 C C      . LEU A 1 233 ? 125.075 131.084 94.078  1.00 63.67  ? 224 LEU A C      1 
ATOM   2328 O O      . LEU A 1 233 ? 124.592 131.380 92.982  1.00 63.67  ? 224 LEU A O      1 
ATOM   2329 C CB     . LEU A 1 233 ? 125.511 128.642 94.342  1.00 63.67  ? 224 LEU A CB     1 
ATOM   2330 C CG     . LEU A 1 233 ? 124.357 128.261 93.416  1.00 63.67  ? 224 LEU A CG     1 
ATOM   2331 C CD1    . LEU A 1 233 ? 124.776 128.302 91.958  1.00 63.67  ? 224 LEU A CD1    1 
ATOM   2332 C CD2    . LEU A 1 233 ? 123.843 126.885 93.784  1.00 63.67  ? 224 LEU A CD2    1 
ATOM   2333 H H      . LEU A 1 233 ? 127.079 129.680 95.856  1.00 63.67  ? 224 LEU A H      1 
ATOM   2334 H HA     . LEU A 1 233 ? 126.624 130.009 93.298  1.00 63.67  ? 224 LEU A HA     1 
ATOM   2335 H HB2    . LEU A 1 233 ? 126.200 127.967 94.236  1.00 63.67  ? 224 LEU A HB2    1 
ATOM   2336 H HB3    . LEU A 1 233 ? 125.171 128.604 95.249  1.00 63.67  ? 224 LEU A HB3    1 
ATOM   2337 H HG     . LEU A 1 233 ? 123.629 128.892 93.535  1.00 63.67  ? 224 LEU A HG     1 
ATOM   2338 H HD11   . LEU A 1 233 ? 125.113 129.187 91.749  1.00 63.67  ? 224 LEU A HD11   1 
ATOM   2339 H HD12   . LEU A 1 233 ? 124.004 128.106 91.404  1.00 63.67  ? 224 LEU A HD12   1 
ATOM   2340 H HD13   . LEU A 1 233 ? 125.468 127.639 91.810  1.00 63.67  ? 224 LEU A HD13   1 
ATOM   2341 H HD21   . LEU A 1 233 ? 123.052 126.690 93.258  1.00 63.67  ? 224 LEU A HD21   1 
ATOM   2342 H HD22   . LEU A 1 233 ? 124.535 126.230 93.599  1.00 63.67  ? 224 LEU A HD22   1 
ATOM   2343 H HD23   . LEU A 1 233 ? 123.622 126.876 94.728  1.00 63.67  ? 224 LEU A HD23   1 
ATOM   2344 N N      . ILE A 1 234 ? 124.691 131.671 95.210  1.00 63.42  ? 225 ILE A N      1 
ATOM   2345 C CA     . ILE A 1 234 ? 123.568 132.604 95.219  1.00 63.42  ? 225 ILE A CA     1 
ATOM   2346 C C      . ILE A 1 234 ? 123.864 133.815 94.345  1.00 63.42  ? 225 ILE A C      1 
ATOM   2347 O O      . ILE A 1 234 ? 123.070 134.183 93.473  1.00 63.42  ? 225 ILE A O      1 
ATOM   2348 C CB     . ILE A 1 234 ? 123.234 133.032 96.659  1.00 63.42  ? 225 ILE A CB     1 
ATOM   2349 C CG1    . ILE A 1 234 ? 122.356 131.983 97.340  1.00 63.42  ? 225 ILE A CG1    1 
ATOM   2350 C CG2    . ILE A 1 234 ? 122.552 134.397 96.665  1.00 63.42  ? 225 ILE A CG2    1 
ATOM   2351 C CD1    . ILE A 1 234 ? 122.142 132.247 98.812  1.00 63.42  ? 225 ILE A CD1    1 
ATOM   2352 H H      . ILE A 1 234 ? 125.064 131.554 95.978  1.00 63.42  ? 225 ILE A H      1 
ATOM   2353 H HA     . ILE A 1 234 ? 122.786 132.161 94.856  1.00 63.42  ? 225 ILE A HA     1 
ATOM   2354 H HB     . ILE A 1 234 ? 124.064 133.103 97.154  1.00 63.42  ? 225 ILE A HB     1 
ATOM   2355 H HG12   . ILE A 1 234 ? 121.485 131.973 96.913  1.00 63.42  ? 225 ILE A HG12   1 
ATOM   2356 H HG13   . ILE A 1 234 ? 122.780 131.115 97.253  1.00 63.42  ? 225 ILE A HG13   1 
ATOM   2357 H HG21   . ILE A 1 234 ? 123.214 135.085 96.496  1.00 63.42  ? 225 ILE A HG21   1 
ATOM   2358 H HG22   . ILE A 1 234 ? 122.150 134.551 97.534  1.00 63.42  ? 225 ILE A HG22   1 
ATOM   2359 H HG23   . ILE A 1 234 ? 121.863 134.418 95.981  1.00 63.42  ? 225 ILE A HG23   1 
ATOM   2360 H HD11   . ILE A 1 234 ? 121.787 131.447 99.228  1.00 63.42  ? 225 ILE A HD11   1 
ATOM   2361 H HD12   . ILE A 1 234 ? 121.517 132.981 98.920  1.00 63.42  ? 225 ILE A HD12   1 
ATOM   2362 H HD13   . ILE A 1 234 ? 122.994 132.479 99.215  1.00 63.42  ? 225 ILE A HD13   1 
ATOM   2363 N N      . ASP A 1 235 ? 125.011 134.459 94.568  1.00 66.05  ? 226 ASP A N      1 
ATOM   2364 C CA     . ASP A 1 235 ? 125.291 135.708 93.867  1.00 66.05  ? 226 ASP A CA     1 
ATOM   2365 C C      . ASP A 1 235 ? 125.322 135.571 92.348  1.00 66.05  ? 226 ASP A C      1 
ATOM   2366 O O      . ASP A 1 235 ? 124.943 136.506 91.635  1.00 66.05  ? 226 ASP A O      1 
ATOM   2367 C CB     . ASP A 1 235 ? 126.492 136.455 94.455  1.00 66.05  ? 226 ASP A CB     1 
ATOM   2368 C CG     . ASP A 1 235 ? 126.518 137.920 94.064  1.00 66.05  ? 226 ASP A CG     1 
ATOM   2369 O OD1    . ASP A 1 235 ? 126.300 138.230 92.873  1.00 66.05  ? 226 ASP A OD1    1 
ATOM   2370 O OD2    . ASP A 1 235 ? 126.750 138.764 94.954  1.00 66.05  ? 226 ASP A OD2    1 
ATOM   2371 H H      . ASP A 1 235 ? 125.627 134.203 95.112  1.00 66.05  ? 226 ASP A H      1 
ATOM   2372 H HA     . ASP A 1 235 ? 126.056 135.148 93.672  1.00 66.05  ? 226 ASP A HA     1 
ATOM   2373 H HB2    . ASP A 1 235 ? 126.449 136.408 95.423  1.00 66.05  ? 226 ASP A HB2    1 
ATOM   2374 H HB3    . ASP A 1 235 ? 127.316 136.052 94.141  1.00 66.05  ? 226 ASP A HB3    1 
ATOM   2375 N N      . SER A 1 236 ? 125.761 134.421 91.832  1.00 66.37  ? 227 SER A N      1 
ATOM   2376 C CA     . SER A 1 236 ? 125.784 134.235 90.386  1.00 66.37  ? 227 SER A CA     1 
ATOM   2377 C C      . SER A 1 236 ? 124.370 134.243 89.816  1.00 66.37  ? 227 SER A C      1 
ATOM   2378 O O      . SER A 1 236 ? 124.089 134.934 88.831  1.00 66.37  ? 227 SER A O      1 
ATOM   2379 C CB     . SER A 1 236 ? 126.502 132.932 90.039  1.00 66.37  ? 227 SER A CB     1 
ATOM   2380 O OG     . SER A 1 236 ? 126.577 132.751 88.636  1.00 66.37  ? 227 SER A OG     1 
ATOM   2381 H H      . SER A 1 236 ? 126.040 133.744 92.285  1.00 66.37  ? 227 SER A H      1 
ATOM   2382 H HA     . SER A 1 236 ? 126.275 134.966 89.980  1.00 66.37  ? 227 SER A HA     1 
ATOM   2383 H HB2    . SER A 1 236 ? 127.401 132.960 90.401  1.00 66.37  ? 227 SER A HB2    1 
ATOM   2384 H HB3    . SER A 1 236 ? 126.013 132.191 90.426  1.00 66.37  ? 227 SER A HB3    1 
ATOM   2385 H HG     . SER A 1 236 ? 125.805 132.667 88.315  1.00 66.37  ? 227 SER A HG     1 
ATOM   2386 N N      . VAL A 1 237 ? 123.466 133.483 90.428  1.00 65.77  ? 228 VAL A N      1 
ATOM   2387 C CA     . VAL A 1 237 ? 122.079 133.391 89.985  1.00 65.77  ? 228 VAL A CA     1 
ATOM   2388 C C      . VAL A 1 237 ? 121.182 133.416 91.213  1.00 65.77  ? 228 VAL A C      1 
ATOM   2389 O O      . VAL A 1 237 ? 121.460 132.732 92.204  1.00 65.77  ? 228 VAL A O      1 
ATOM   2390 C CB     . VAL A 1 237 ? 121.827 132.122 89.151  1.00 65.77  ? 228 VAL A CB     1 
ATOM   2391 C CG1    . VAL A 1 237 ? 122.705 132.126 87.912  1.00 65.77  ? 228 VAL A CG1    1 
ATOM   2392 C CG2    . VAL A 1 237 ? 122.078 130.878 89.987  1.00 65.77  ? 228 VAL A CG2    1 
ATOM   2393 H H      . VAL A 1 237 ? 123.639 132.999 91.117  1.00 65.77  ? 228 VAL A H      1 
ATOM   2394 H HA     . VAL A 1 237 ? 121.863 134.164 89.439  1.00 65.77  ? 228 VAL A HA     1 
ATOM   2395 H HB     . VAL A 1 237 ? 120.902 132.114 88.859  1.00 65.77  ? 228 VAL A HB     1 
ATOM   2396 H HG11   . VAL A 1 237 ? 122.541 132.942 87.414  1.00 65.77  ? 228 VAL A HG11   1 
ATOM   2397 H HG12   . VAL A 1 237 ? 122.487 131.354 87.367  1.00 65.77  ? 228 VAL A HG12   1 
ATOM   2398 H HG13   . VAL A 1 237 ? 123.635 132.086 88.185  1.00 65.77  ? 228 VAL A HG13   1 
ATOM   2399 H HG21   . VAL A 1 237 ? 122.086 130.104 89.403  1.00 65.77  ? 228 VAL A HG21   1 
ATOM   2400 H HG22   . VAL A 1 237 ? 122.936 130.962 90.432  1.00 65.77  ? 228 VAL A HG22   1 
ATOM   2401 H HG23   . VAL A 1 237 ? 121.372 130.786 90.645  1.00 65.77  ? 228 VAL A HG23   1 
ATOM   2402 N N      . GLY A 1 238 ? 120.099 134.184 91.141  1.00 64.35  ? 229 GLY A N      1 
ATOM   2403 C CA     . GLY A 1 238 ? 119.302 134.494 92.312  1.00 64.35  ? 229 GLY A CA     1 
ATOM   2404 C C      . GLY A 1 238 ? 118.692 133.308 93.030  1.00 64.35  ? 229 GLY A C      1 
ATOM   2405 O O      . GLY A 1 238 ? 118.932 132.150 92.673  1.00 64.35  ? 229 GLY A O      1 
ATOM   2406 H H      . GLY A 1 238 ? 119.807 134.540 90.415  1.00 64.35  ? 229 GLY A H      1 
ATOM   2407 H HA2    . GLY A 1 238 ? 119.857 134.974 92.946  1.00 64.35  ? 229 GLY A HA2    1 
ATOM   2408 H HA3    . GLY A 1 238 ? 118.577 135.081 92.049  1.00 64.35  ? 229 GLY A HA3    1 
ATOM   2409 N N      . LEU A 1 239 ? 117.888 133.604 94.056  1.00 63.26  ? 230 LEU A N      1 
ATOM   2410 C CA     . LEU A 1 239 ? 117.263 132.555 94.856  1.00 63.26  ? 230 LEU A CA     1 
ATOM   2411 C C      . LEU A 1 239 ? 116.525 131.551 93.984  1.00 63.26  ? 230 LEU A C      1 
ATOM   2412 O O      . LEU A 1 239 ? 116.611 130.338 94.208  1.00 63.26  ? 230 LEU A O      1 
ATOM   2413 C CB     . LEU A 1 239 ? 116.298 133.180 95.865  1.00 63.26  ? 230 LEU A CB     1 
ATOM   2414 C CG     . LEU A 1 239 ? 115.246 132.251 96.477  1.00 63.26  ? 230 LEU A CG     1 
ATOM   2415 C CD1    . LEU A 1 239 ? 115.905 131.126 97.253  1.00 63.26  ? 230 LEU A CD1    1 
ATOM   2416 C CD2    . LEU A 1 239 ? 114.304 133.033 97.367  1.00 63.26  ? 230 LEU A CD2    1 
ATOM   2417 H H      . LEU A 1 239 ? 117.690 134.403 94.307  1.00 63.26  ? 230 LEU A H      1 
ATOM   2418 H HA     . LEU A 1 239 ? 117.951 132.084 95.349  1.00 63.26  ? 230 LEU A HA     1 
ATOM   2419 H HB2    . LEU A 1 239 ? 116.820 133.546 96.595  1.00 63.26  ? 230 LEU A HB2    1 
ATOM   2420 H HB3    . LEU A 1 239 ? 115.822 133.898 95.419  1.00 63.26  ? 230 LEU A HB3    1 
ATOM   2421 H HG     . LEU A 1 239 ? 114.710 131.857 95.772  1.00 63.26  ? 230 LEU A HG     1 
ATOM   2422 H HD11   . LEU A 1 239 ? 115.215 130.566 97.642  1.00 63.26  ? 230 LEU A HD11   1 
ATOM   2423 H HD12   . LEU A 1 239 ? 116.455 130.602 96.650  1.00 63.26  ? 230 LEU A HD12   1 
ATOM   2424 H HD13   . LEU A 1 239 ? 116.455 131.509 97.954  1.00 63.26  ? 230 LEU A HD13   1 
ATOM   2425 H HD21   . LEU A 1 239 ? 113.828 133.685 96.830  1.00 63.26  ? 230 LEU A HD21   1 
ATOM   2426 H HD22   . LEU A 1 239 ? 114.820 133.483 98.054  1.00 63.26  ? 230 LEU A HD22   1 
ATOM   2427 H HD23   . LEU A 1 239 ? 113.675 132.418 97.775  1.00 63.26  ? 230 LEU A HD23   1 
ATOM   2428 N N      . PHE A 1 240 ? 115.780 132.040 92.994  1.00 65.14  ? 231 PHE A N      1 
ATOM   2429 C CA     . PHE A 1 240 ? 114.966 131.151 92.174  1.00 65.14  ? 231 PHE A CA     1 
ATOM   2430 C C      . PHE A 1 240 ? 115.836 130.130 91.454  1.00 65.14  ? 231 PHE A C      1 
ATOM   2431 O O      . PHE A 1 240 ? 115.557 128.926 91.484  1.00 65.14  ? 231 PHE A O      1 
ATOM   2432 C CB     . PHE A 1 240 ? 114.152 131.973 91.176  1.00 65.14  ? 231 PHE A CB     1 
ATOM   2433 C CG     . PHE A 1 240 ? 113.435 133.129 91.799  1.00 65.14  ? 231 PHE A CG     1 
ATOM   2434 C CD1    . PHE A 1 240 ? 112.848 133.002 93.044  1.00 65.14  ? 231 PHE A CD1    1 
ATOM   2435 C CD2    . PHE A 1 240 ? 113.364 134.347 91.151  1.00 65.14  ? 231 PHE A CD2    1 
ATOM   2436 C CE1    . PHE A 1 240 ? 112.193 134.062 93.624  1.00 65.14  ? 231 PHE A CE1    1 
ATOM   2437 C CE2    . PHE A 1 240 ? 112.710 135.412 91.729  1.00 65.14  ? 231 PHE A CE2    1 
ATOM   2438 C CZ     . PHE A 1 240 ? 112.124 135.269 92.967  1.00 65.14  ? 231 PHE A CZ     1 
ATOM   2439 H H      . PHE A 1 240 ? 115.737 132.871 92.779  1.00 65.14  ? 231 PHE A H      1 
ATOM   2440 H HA     . PHE A 1 240 ? 114.348 130.668 92.745  1.00 65.14  ? 231 PHE A HA     1 
ATOM   2441 H HB2    . PHE A 1 240 ? 114.751 132.324 90.498  1.00 65.14  ? 231 PHE A HB2    1 
ATOM   2442 H HB3    . PHE A 1 240 ? 113.488 131.399 90.764  1.00 65.14  ? 231 PHE A HB3    1 
ATOM   2443 H HD1    . PHE A 1 240 ? 112.891 132.188 93.492  1.00 65.14  ? 231 PHE A HD1    1 
ATOM   2444 H HD2    . PHE A 1 240 ? 113.758 134.447 90.315  1.00 65.14  ? 231 PHE A HD2    1 
ATOM   2445 H HE1    . PHE A 1 240 ? 111.798 133.964 94.460  1.00 65.14  ? 231 PHE A HE1    1 
ATOM   2446 H HE2    . PHE A 1 240 ? 112.664 136.227 91.283  1.00 65.14  ? 231 PHE A HE2    1 
ATOM   2447 H HZ     . PHE A 1 240 ? 111.681 135.987 93.358  1.00 65.14  ? 231 PHE A HZ     1 
ATOM   2448 N N      . TYR A 1 241 ? 116.910 130.593 90.815  1.00 66.39  ? 232 TYR A N      1 
ATOM   2449 C CA     . TYR A 1 241 ? 117.822 129.669 90.155  1.00 66.39  ? 232 TYR A CA     1 
ATOM   2450 C C      . TYR A 1 241 ? 118.480 128.736 91.161  1.00 66.39  ? 232 TYR A C      1 
ATOM   2451 O O      . TYR A 1 241 ? 118.712 127.560 90.865  1.00 66.39  ? 232 TYR A O      1 
ATOM   2452 C CB     . TYR A 1 241 ? 118.881 130.441 89.375  1.00 66.39  ? 232 TYR A CB     1 
ATOM   2453 C CG     . TYR A 1 241 ? 118.461 130.820 87.976  1.00 66.39  ? 232 TYR A CG     1 
ATOM   2454 C CD1    . TYR A 1 241 ? 118.453 129.878 86.957  1.00 66.39  ? 232 TYR A CD1    1 
ATOM   2455 C CD2    . TYR A 1 241 ? 118.086 132.119 87.669  1.00 66.39  ? 232 TYR A CD2    1 
ATOM   2456 C CE1    . TYR A 1 241 ? 118.076 130.216 85.674  1.00 66.39  ? 232 TYR A CE1    1 
ATOM   2457 C CE2    . TYR A 1 241 ? 117.707 132.468 86.387  1.00 66.39  ? 232 TYR A CE2    1 
ATOM   2458 C CZ     . TYR A 1 241 ? 117.704 131.512 85.394  1.00 66.39  ? 232 TYR A CZ     1 
ATOM   2459 O OH     . TYR A 1 241 ? 117.329 131.852 84.115  1.00 66.39  ? 232 TYR A OH     1 
ATOM   2460 H H      . TYR A 1 241 ? 117.128 131.423 90.751  1.00 66.39  ? 232 TYR A H      1 
ATOM   2461 H HA     . TYR A 1 241 ? 117.321 129.127 89.525  1.00 66.39  ? 232 TYR A HA     1 
ATOM   2462 H HB2    . TYR A 1 241 ? 119.088 131.258 89.855  1.00 66.39  ? 232 TYR A HB2    1 
ATOM   2463 H HB3    . TYR A 1 241 ? 119.675 129.890 89.304  1.00 66.39  ? 232 TYR A HB3    1 
ATOM   2464 H HD1    . TYR A 1 241 ? 118.704 129.002 87.143  1.00 66.39  ? 232 TYR A HD1    1 
ATOM   2465 H HD2    . TYR A 1 241 ? 118.087 132.766 88.337  1.00 66.39  ? 232 TYR A HD2    1 
ATOM   2466 H HE1    . TYR A 1 241 ? 118.074 129.573 85.002  1.00 66.39  ? 232 TYR A HE1    1 
ATOM   2467 H HE2    . TYR A 1 241 ? 117.455 133.343 86.195  1.00 66.39  ? 232 TYR A HE2    1 
ATOM   2468 H HH     . TYR A 1 241 ? 117.383 131.181 83.612  1.00 66.39  ? 232 TYR A HH     1 
ATOM   2469 N N      . THR A 1 242 ? 118.803 129.241 92.352  1.00 64.66  ? 233 THR A N      1 
ATOM   2470 C CA     . THR A 1 242 ? 119.443 128.397 93.357  1.00 64.66  ? 233 THR A CA     1 
ATOM   2471 C C      . THR A 1 242 ? 118.542 127.230 93.743  1.00 64.66  ? 233 THR A C      1 
ATOM   2472 O O      . THR A 1 242 ? 118.987 126.077 93.804  1.00 64.66  ? 233 THR A O      1 
ATOM   2473 C CB     . THR A 1 242 ? 119.798 129.228 94.588  1.00 64.66  ? 233 THR A CB     1 
ATOM   2474 O OG1    . THR A 1 242 ? 118.610 129.816 95.129  1.00 64.66  ? 233 THR A OG1    1 
ATOM   2475 C CG2    . THR A 1 242 ? 120.786 130.325 94.226  1.00 64.66  ? 233 THR A CG2    1 
ATOM   2476 H H      . THR A 1 242 ? 118.664 130.053 92.599  1.00 64.66  ? 233 THR A H      1 
ATOM   2477 H HA     . THR A 1 242 ? 120.264 128.035 92.990  1.00 64.66  ? 233 THR A HA     1 
ATOM   2478 H HB     . THR A 1 242 ? 120.207 128.656 95.256  1.00 64.66  ? 233 THR A HB     1 
ATOM   2479 H HG1    . THR A 1 242 ? 118.787 130.209 95.849  1.00 64.66  ? 233 THR A HG1    1 
ATOM   2480 H HG21   . THR A 1 242 ? 121.568 130.264 94.797  1.00 64.66  ? 233 THR A HG21   1 
ATOM   2481 H HG22   . THR A 1 242 ? 121.064 130.231 93.302  1.00 64.66  ? 233 THR A HG22   1 
ATOM   2482 H HG23   . THR A 1 242 ? 120.376 131.195 94.347  1.00 64.66  ? 233 THR A HG23   1 
ATOM   2483 N N      . LEU A 1 243 ? 117.265 127.510 94.007  1.00 63.66  ? 234 LEU A N      1 
ATOM   2484 C CA     . LEU A 1 243 ? 116.334 126.437 94.333  1.00 63.66  ? 234 LEU A CA     1 
ATOM   2485 C C      . LEU A 1 243 ? 116.079 125.541 93.132  1.00 63.66  ? 234 LEU A C      1 
ATOM   2486 O O      . LEU A 1 243 ? 115.894 124.330 93.293  1.00 63.66  ? 234 LEU A O      1 
ATOM   2487 C CB     . LEU A 1 243 ? 115.016 127.013 94.848  1.00 63.66  ? 234 LEU A CB     1 
ATOM   2488 C CG     . LEU A 1 243 ? 115.058 127.686 96.220  1.00 63.66  ? 234 LEU A CG     1 
ATOM   2489 C CD1    . LEU A 1 243 ? 113.689 128.231 96.589  1.00 63.66  ? 234 LEU A CD1    1 
ATOM   2490 C CD2    . LEU A 1 243 ? 115.548 126.719 97.283  1.00 63.66  ? 234 LEU A CD2    1 
ATOM   2491 H H      . LEU A 1 243 ? 116.920 128.298 94.002  1.00 63.66  ? 234 LEU A H      1 
ATOM   2492 H HA     . LEU A 1 243 ? 116.721 125.888 95.033  1.00 63.66  ? 234 LEU A HA     1 
ATOM   2493 H HB2    . LEU A 1 243 ? 114.705 127.676 94.211  1.00 63.66  ? 234 LEU A HB2    1 
ATOM   2494 H HB3    . LEU A 1 243 ? 114.369 126.292 94.901  1.00 63.66  ? 234 LEU A HB3    1 
ATOM   2495 H HG     . LEU A 1 243 ? 115.677 128.432 96.187  1.00 63.66  ? 234 LEU A HG     1 
ATOM   2496 H HD11   . LEU A 1 243 ? 113.745 128.667 97.453  1.00 63.66  ? 234 LEU A HD11   1 
ATOM   2497 H HD12   . LEU A 1 243 ? 113.058 127.495 96.630  1.00 63.66  ? 234 LEU A HD12   1 
ATOM   2498 H HD13   . LEU A 1 243 ? 113.411 128.869 95.913  1.00 63.66  ? 234 LEU A HD13   1 
ATOM   2499 H HD21   . LEU A 1 243 ? 115.376 127.100 98.158  1.00 63.66  ? 234 LEU A HD21   1 
ATOM   2500 H HD22   . LEU A 1 243 ? 116.500 126.576 97.167  1.00 63.66  ? 234 LEU A HD22   1 
ATOM   2501 H HD23   . LEU A 1 243 ? 115.071 125.879 97.189  1.00 63.66  ? 234 LEU A HD23   1 
ATOM   2502 N N      . ARG A 1 244 ? 116.065 126.111 91.928  1.00 66.95  ? 235 ARG A N      1 
ATOM   2503 C CA     . ARG A 1 244 ? 115.857 125.318 90.725  1.00 66.95  ? 235 ARG A CA     1 
ATOM   2504 C C      . ARG A 1 244 ? 117.043 124.411 90.425  1.00 66.95  ? 235 ARG A C      1 
ATOM   2505 O O      . ARG A 1 244 ? 116.878 123.402 89.731  1.00 66.95  ? 235 ARG A O      1 
ATOM   2506 C CB     . ARG A 1 244 ? 115.588 126.259 89.549  1.00 66.95  ? 235 ARG A CB     1 
ATOM   2507 C CG     . ARG A 1 244 ? 115.000 125.609 88.310  1.00 66.95  ? 235 ARG A CG     1 
ATOM   2508 C CD     . ARG A 1 244 ? 114.329 126.662 87.443  1.00 66.95  ? 235 ARG A CD     1 
ATOM   2509 N NE     . ARG A 1 244 ? 114.399 126.352 86.021  1.00 66.95  ? 235 ARG A NE     1 
ATOM   2510 C CZ     . ARG A 1 244 ? 114.009 127.176 85.058  1.00 66.95  ? 235 ARG A CZ     1 
ATOM   2511 N NH1    . ARG A 1 244 ? 113.503 128.368 85.330  1.00 66.95  ? 235 ARG A NH1    1 
ATOM   2512 N NH2    . ARG A 1 244 ? 114.133 126.797 83.789  1.00 66.95  ? 235 ARG A NH2    1 
ATOM   2513 H H      . ARG A 1 244 ? 116.172 126.952 91.784  1.00 66.95  ? 235 ARG A H      1 
ATOM   2514 H HA     . ARG A 1 244 ? 115.073 124.759 90.847  1.00 66.95  ? 235 ARG A HA     1 
ATOM   2515 H HB2    . ARG A 1 244 ? 114.966 126.943 89.841  1.00 66.95  ? 235 ARG A HB2    1 
ATOM   2516 H HB3    . ARG A 1 244 ? 116.426 126.672 89.290  1.00 66.95  ? 235 ARG A HB3    1 
ATOM   2517 H HG2    . ARG A 1 244 ? 115.707 125.188 87.796  1.00 66.95  ? 235 ARG A HG2    1 
ATOM   2518 H HG3    . ARG A 1 244 ? 114.334 124.955 88.572  1.00 66.95  ? 235 ARG A HG3    1 
ATOM   2519 H HD2    . ARG A 1 244 ? 113.394 126.725 87.690  1.00 66.95  ? 235 ARG A HD2    1 
ATOM   2520 H HD3    . ARG A 1 244 ? 114.768 127.515 87.585  1.00 66.95  ? 235 ARG A HD3    1 
ATOM   2521 H HE     . ARG A 1 244 ? 114.666 125.567 85.794  1.00 66.95  ? 235 ARG A HE     1 
ATOM   2522 H HH11   . ARG A 1 244 ? 113.418 128.626 86.146  1.00 66.95  ? 235 ARG A HH11   1 
ATOM   2523 H HH12   . ARG A 1 244 ? 113.257 128.886 84.690  1.00 66.95  ? 235 ARG A HH12   1 
ATOM   2524 H HH21   . ARG A 1 244 ? 114.461 126.025 83.601  1.00 66.95  ? 235 ARG A HH21   1 
ATOM   2525 H HH22   . ARG A 1 244 ? 113.883 127.323 83.157  1.00 66.95  ? 235 ARG A HH22   1 
ATOM   2526 N N      . VAL A 1 245 ? 118.225 124.746 90.932  1.00 63.67  ? 236 VAL A N      1 
ATOM   2527 C CA     . VAL A 1 245 ? 119.425 123.952 90.711  1.00 63.67  ? 236 VAL A CA     1 
ATOM   2528 C C      . VAL A 1 245 ? 119.640 122.935 91.824  1.00 63.67  ? 236 VAL A C      1 
ATOM   2529 O O      . VAL A 1 245 ? 120.153 121.844 91.576  1.00 63.67  ? 236 VAL A O      1 
ATOM   2530 C CB     . VAL A 1 245 ? 120.652 124.875 90.561  1.00 63.67  ? 236 VAL A CB     1 
ATOM   2531 C CG1    . VAL A 1 245 ? 121.934 124.060 90.581  1.00 63.67  ? 236 VAL A CG1    1 
ATOM   2532 C CG2    . VAL A 1 245 ? 120.551 125.678 89.278  1.00 63.67  ? 236 VAL A CG2    1 
ATOM   2533 H H      . VAL A 1 245 ? 118.359 125.443 91.419  1.00 63.67  ? 236 VAL A H      1 
ATOM   2534 H HA     . VAL A 1 245 ? 119.324 123.461 89.881  1.00 63.67  ? 236 VAL A HA     1 
ATOM   2535 H HB     . VAL A 1 245 ? 120.677 125.497 91.306  1.00 63.67  ? 236 VAL A HB     1 
ATOM   2536 H HG11   . VAL A 1 245 ? 122.151 123.828 91.497  1.00 63.67  ? 236 VAL A HG11   1 
ATOM   2537 H HG12   . VAL A 1 245 ? 122.650 124.591 90.198  1.00 63.67  ? 236 VAL A HG12   1 
ATOM   2538 H HG13   . VAL A 1 245 ? 121.804 123.255 90.054  1.00 63.67  ? 236 VAL A HG13   1 
ATOM   2539 H HG21   . VAL A 1 245 ? 120.693 125.083 88.525  1.00 63.67  ? 236 VAL A HG21   1 
ATOM   2540 H HG22   . VAL A 1 245 ? 121.230 126.371 89.286  1.00 63.67  ? 236 VAL A HG22   1 
ATOM   2541 H HG23   . VAL A 1 245 ? 119.670 126.079 89.221  1.00 63.67  ? 236 VAL A HG23   1 
ATOM   2542 N N      . LEU A 1 246 ? 119.247 123.268 93.055  1.00 62.40  ? 237 LEU A N      1 
ATOM   2543 C CA     . LEU A 1 246 ? 119.361 122.309 94.150  1.00 62.40  ? 237 LEU A CA     1 
ATOM   2544 C C      . LEU A 1 246 ? 118.569 121.034 93.897  1.00 62.40  ? 237 LEU A C      1 
ATOM   2545 O O      . LEU A 1 246 ? 118.679 120.090 94.685  1.00 62.40  ? 237 LEU A O      1 
ATOM   2546 C CB     . LEU A 1 246 ? 118.902 122.946 95.462  1.00 62.40  ? 237 LEU A CB     1 
ATOM   2547 C CG     . LEU A 1 246 ? 119.916 123.859 96.153  1.00 62.40  ? 237 LEU A CG     1 
ATOM   2548 C CD1    . LEU A 1 246 ? 119.277 124.583 97.328  1.00 62.40  ? 237 LEU A CD1    1 
ATOM   2549 C CD2    . LEU A 1 246 ? 121.127 123.061 96.614  1.00 62.40  ? 237 LEU A CD2    1 
ATOM   2550 H H      . LEU A 1 246 ? 118.916 124.030 93.278  1.00 62.40  ? 237 LEU A H      1 
ATOM   2551 H HA     . LEU A 1 246 ? 120.292 122.058 94.244  1.00 62.40  ? 237 LEU A HA     1 
ATOM   2552 H HB2    . LEU A 1 246 ? 118.110 123.477 95.283  1.00 62.40  ? 237 LEU A HB2    1 
ATOM   2553 H HB3    . LEU A 1 246 ? 118.680 122.235 96.084  1.00 62.40  ? 237 LEU A HB3    1 
ATOM   2554 H HG     . LEU A 1 246 ? 120.222 124.528 95.521  1.00 62.40  ? 237 LEU A HG     1 
ATOM   2555 H HD11   . LEU A 1 246 ? 118.525 125.104 97.007  1.00 62.40  ? 237 LEU A HD11   1 
ATOM   2556 H HD12   . LEU A 1 246 ? 119.937 125.168 97.733  1.00 62.40  ? 237 LEU A HD12   1 
ATOM   2557 H HD13   . LEU A 1 246 ? 118.974 123.928 97.976  1.00 62.40  ? 237 LEU A HD13   1 
ATOM   2558 H HD21   . LEU A 1 246 ? 121.664 123.615 97.202  1.00 62.40  ? 237 LEU A HD21   1 
ATOM   2559 H HD22   . LEU A 1 246 ? 120.822 122.273 97.090  1.00 62.40  ? 237 LEU A HD22   1 
ATOM   2560 H HD23   . LEU A 1 246 ? 121.648 122.798 95.840  1.00 62.40  ? 237 LEU A HD23   1 
ATOM   2561 N N      . CYS A 1 247 ? 117.780 120.982 92.823  1.00 62.41  ? 238 CYS A N      1 
ATOM   2562 C CA     . CYS A 1 247 ? 117.056 119.771 92.474  1.00 62.41  ? 238 CYS A CA     1 
ATOM   2563 C C      . CYS A 1 247 ? 117.983 118.623 92.106  1.00 62.41  ? 238 CYS A C      1 
ATOM   2564 O O      . CYS A 1 247 ? 117.516 117.485 92.003  1.00 62.41  ? 238 CYS A O      1 
ATOM   2565 C CB     . CYS A 1 247 ? 116.113 120.052 91.305  1.00 62.41  ? 238 CYS A CB     1 
ATOM   2566 S SG     . CYS A 1 247 ? 116.965 120.449 89.766  1.00 62.41  ? 238 CYS A SG     1 
ATOM   2567 H H      . CYS A 1 247 ? 117.639 121.637 92.287  1.00 62.41  ? 238 CYS A H      1 
ATOM   2568 H HA     . CYS A 1 247 ? 116.520 119.492 93.233  1.00 62.41  ? 238 CYS A HA     1 
ATOM   2569 H HB2    . CYS A 1 247 ? 115.576 119.262 91.147  1.00 62.41  ? 238 CYS A HB2    1 
ATOM   2570 H HB3    . CYS A 1 247 ? 115.542 120.801 91.534  1.00 62.41  ? 238 CYS A HB3    1 
ATOM   2571 H HG     . CYS A 1 247 ? 117.659 119.521 89.456  1.00 62.41  ? 238 CYS A HG     1 
ATOM   2572 N N      . ILE A 1 248 ? 119.271 118.892 91.884  1.00 63.40  ? 239 ILE A N      1 
ATOM   2573 C CA     . ILE A 1 248 ? 120.206 117.824 91.538  1.00 63.40  ? 239 ILE A CA     1 
ATOM   2574 C C      . ILE A 1 248 ? 120.301 116.810 92.671  1.00 63.40  ? 239 ILE A C      1 
ATOM   2575 O O      . ILE A 1 248 ? 120.351 115.596 92.435  1.00 63.40  ? 239 ILE A O      1 
ATOM   2576 C CB     . ILE A 1 248 ? 121.583 118.417 91.190  1.00 63.40  ? 239 ILE A CB     1 
ATOM   2577 C CG1    . ILE A 1 248 ? 121.497 119.203 89.879  1.00 63.40  ? 239 ILE A CG1    1 
ATOM   2578 C CG2    . ILE A 1 248 ? 122.626 117.314 91.099  1.00 63.40  ? 239 ILE A CG2    1 
ATOM   2579 C CD1    . ILE A 1 248 ? 122.726 120.033 89.573  1.00 63.40  ? 239 ILE A CD1    1 
ATOM   2580 H H      . ILE A 1 248 ? 119.625 119.675 91.925  1.00 63.40  ? 239 ILE A H      1 
ATOM   2581 H HA     . ILE A 1 248 ? 119.875 117.361 90.753  1.00 63.40  ? 239 ILE A HA     1 
ATOM   2582 H HB     . ILE A 1 248 ? 121.843 119.028 91.898  1.00 63.40  ? 239 ILE A HB     1 
ATOM   2583 H HG12   . ILE A 1 248 ? 121.374 118.577 89.149  1.00 63.40  ? 239 ILE A HG12   1 
ATOM   2584 H HG13   . ILE A 1 248 ? 120.738 119.805 89.925  1.00 63.40  ? 239 ILE A HG13   1 
ATOM   2585 H HG21   . ILE A 1 248 ? 122.874 117.037 91.995  1.00 63.40  ? 239 ILE A HG21   1 
ATOM   2586 H HG22   . ILE A 1 248 ? 123.406 117.649 90.633  1.00 63.40  ? 239 ILE A HG22   1 
ATOM   2587 H HG23   . ILE A 1 248 ? 122.249 116.564 90.612  1.00 63.40  ? 239 ILE A HG23   1 
ATOM   2588 H HD11   . ILE A 1 248 ? 122.524 120.635 88.840  1.00 63.40  ? 239 ILE A HD11   1 
ATOM   2589 H HD12   . ILE A 1 248 ? 122.965 120.543 90.363  1.00 63.40  ? 239 ILE A HD12   1 
ATOM   2590 H HD13   . ILE A 1 248 ? 123.454 119.443 89.326  1.00 63.40  ? 239 ILE A HD13   1 
ATOM   2591 N N      . PHE A 1 249 ? 120.347 117.287 93.916  1.00 62.06  ? 240 PHE A N      1 
ATOM   2592 C CA     . PHE A 1 249 ? 120.413 116.372 95.051  1.00 62.06  ? 240 PHE A CA     1 
ATOM   2593 C C      . PHE A 1 249 ? 119.178 115.484 95.106  1.00 62.06  ? 240 PHE A C      1 
ATOM   2594 O O      . PHE A 1 249 ? 119.281 114.270 95.311  1.00 62.06  ? 240 PHE A O      1 
ATOM   2595 C CB     . PHE A 1 249 ? 120.568 117.157 96.353  1.00 62.06  ? 240 PHE A CB     1 
ATOM   2596 C CG     . PHE A 1 249 ? 121.916 117.794 96.516  1.00 62.06  ? 240 PHE A CG     1 
ATOM   2597 C CD1    . PHE A 1 249 ? 122.987 117.062 96.993  1.00 62.06  ? 240 PHE A CD1    1 
ATOM   2598 C CD2    . PHE A 1 249 ? 122.110 119.127 96.197  1.00 62.06  ? 240 PHE A CD2    1 
ATOM   2599 C CE1    . PHE A 1 249 ? 124.228 117.645 97.145  1.00 62.06  ? 240 PHE A CE1    1 
ATOM   2600 C CE2    . PHE A 1 249 ? 123.350 119.715 96.347  1.00 62.06  ? 240 PHE A CE2    1 
ATOM   2601 C CZ     . PHE A 1 249 ? 124.410 118.973 96.822  1.00 62.06  ? 240 PHE A CZ     1 
ATOM   2602 H H      . PHE A 1 249 ? 120.341 118.121 94.126  1.00 62.06  ? 240 PHE A H      1 
ATOM   2603 H HA     . PHE A 1 249 ? 121.190 115.800 94.950  1.00 62.06  ? 240 PHE A HA     1 
ATOM   2604 H HB2    . PHE A 1 249 ? 119.902 117.861 96.376  1.00 62.06  ? 240 PHE A HB2    1 
ATOM   2605 H HB3    . PHE A 1 249 ? 120.434 116.552 97.100  1.00 62.06  ? 240 PHE A HB3    1 
ATOM   2606 H HD1    . PHE A 1 249 ? 122.870 116.166 97.212  1.00 62.06  ? 240 PHE A HD1    1 
ATOM   2607 H HD2    . PHE A 1 249 ? 121.398 119.631 95.875  1.00 62.06  ? 240 PHE A HD2    1 
ATOM   2608 H HE1    . PHE A 1 249 ? 124.942 117.143 97.466  1.00 62.06  ? 240 PHE A HE1    1 
ATOM   2609 H HE2    . PHE A 1 249 ? 123.470 120.611 96.128  1.00 62.06  ? 240 PHE A HE2    1 
ATOM   2610 H HZ     . PHE A 1 249 ? 125.246 119.368 96.925  1.00 62.06  ? 240 PHE A HZ     1 
ATOM   2611 N N      . MET A 1 250 ? 117.996 116.073 94.922  1.00 63.11  ? 241 MET A N      1 
ATOM   2612 C CA     . MET A 1 250 ? 116.773 115.279 94.942  1.00 63.11  ? 241 MET A CA     1 
ATOM   2613 C C      . MET A 1 250 ? 116.741 114.293 93.783  1.00 63.11  ? 241 MET A C      1 
ATOM   2614 O O      . MET A 1 250 ? 116.253 113.168 93.929  1.00 63.11  ? 241 MET A O      1 
ATOM   2615 C CB     . MET A 1 250 ? 115.550 116.194 94.906  1.00 63.11  ? 241 MET A CB     1 
ATOM   2616 C CG     . MET A 1 250 ? 115.286 116.946 96.206  1.00 63.11  ? 241 MET A CG     1 
ATOM   2617 S SD     . MET A 1 250 ? 114.722 115.887 97.554  1.00 63.11  ? 241 MET A SD     1 
ATOM   2618 C CE     . MET A 1 250 ? 116.236 115.651 98.480  1.00 63.11  ? 241 MET A CE     1 
ATOM   2619 H H      . MET A 1 250 ? 117.878 116.914 94.785  1.00 63.11  ? 241 MET A H      1 
ATOM   2620 H HA     . MET A 1 250 ? 116.742 114.777 95.772  1.00 63.11  ? 241 MET A HA     1 
ATOM   2621 H HB2    . MET A 1 250 ? 115.676 116.852 94.205  1.00 63.11  ? 241 MET A HB2    1 
ATOM   2622 H HB3    . MET A 1 250 ? 114.766 115.656 94.712  1.00 63.11  ? 241 MET A HB3    1 
ATOM   2623 H HG2    . MET A 1 250 ? 116.106 117.379 96.490  1.00 63.11  ? 241 MET A HG2    1 
ATOM   2624 H HG3    . MET A 1 250 ? 114.598 117.611 96.047  1.00 63.11  ? 241 MET A HG3    1 
ATOM   2625 H HE1    . MET A 1 250 ? 116.038 115.141 99.281  1.00 63.11  ? 241 MET A HE1    1 
ATOM   2626 H HE2    . MET A 1 250 ? 116.874 115.170 97.932  1.00 63.11  ? 241 MET A HE2    1 
ATOM   2627 H HE3    . MET A 1 250 ? 116.595 116.519 98.722  1.00 63.11  ? 241 MET A HE3    1 
ATOM   2628 N N      . PHE A 1 251 ? 117.254 114.694 92.620  1.00 63.07  ? 242 PHE A N      1 
ATOM   2629 C CA     . PHE A 1 251 ? 117.290 113.785 91.481  1.00 63.07  ? 242 PHE A CA     1 
ATOM   2630 C C      . PHE A 1 251 ? 118.210 112.598 91.749  1.00 63.07  ? 242 PHE A C      1 
ATOM   2631 O O      . PHE A 1 251 ? 117.863 111.448 91.444  1.00 63.07  ? 242 PHE A O      1 
ATOM   2632 C CB     . PHE A 1 251 ? 117.734 114.543 90.233  1.00 63.07  ? 242 PHE A CB     1 
ATOM   2633 C CG     . PHE A 1 251 ? 117.432 113.829 88.953  1.00 63.07  ? 242 PHE A CG     1 
ATOM   2634 C CD1    . PHE A 1 251 ? 116.159 113.858 88.416  1.00 63.07  ? 242 PHE A CD1    1 
ATOM   2635 C CD2    . PHE A 1 251 ? 118.420 113.132 88.284  1.00 63.07  ? 242 PHE A CD2    1 
ATOM   2636 C CE1    . PHE A 1 251 ? 115.877 113.202 87.238  1.00 63.07  ? 242 PHE A CE1    1 
ATOM   2637 C CE2    . PHE A 1 251 ? 118.144 112.474 87.105  1.00 63.07  ? 242 PHE A CE2    1 
ATOM   2638 C CZ     . PHE A 1 251 ? 116.871 112.509 86.582  1.00 63.07  ? 242 PHE A CZ     1 
ATOM   2639 H H      . PHE A 1 251 ? 117.582 115.474 92.469  1.00 63.07  ? 242 PHE A H      1 
ATOM   2640 H HA     . PHE A 1 251 ? 116.396 113.442 91.321  1.00 63.07  ? 242 PHE A HA     1 
ATOM   2641 H HB2    . PHE A 1 251 ? 117.278 115.399 90.209  1.00 63.07  ? 242 PHE A HB2    1 
ATOM   2642 H HB3    . PHE A 1 251 ? 118.693 114.682 90.276  1.00 63.07  ? 242 PHE A HB3    1 
ATOM   2643 H HD1    . PHE A 1 251 ? 115.485 114.324 88.856  1.00 63.07  ? 242 PHE A HD1    1 
ATOM   2644 H HD2    . PHE A 1 251 ? 119.281 113.105 88.634  1.00 63.07  ? 242 PHE A HD2    1 
ATOM   2645 H HE1    . PHE A 1 251 ? 115.017 113.227 86.885  1.00 63.07  ? 242 PHE A HE1    1 
ATOM   2646 H HE2    . PHE A 1 251 ? 118.816 112.008 86.664  1.00 63.07  ? 242 PHE A HE2    1 
ATOM   2647 H HZ     . PHE A 1 251 ? 116.682 112.066 85.786  1.00 63.07  ? 242 PHE A HZ     1 
ATOM   2648 N N      . VAL A 1 252 ? 119.386 112.853 92.325  1.00 63.73  ? 243 VAL A N      1 
ATOM   2649 C CA     . VAL A 1 252 ? 120.297 111.759 92.649  1.00 63.73  ? 243 VAL A CA     1 
ATOM   2650 C C      . VAL A 1 252 ? 119.689 110.862 93.717  1.00 63.73  ? 243 VAL A C      1 
ATOM   2651 O O      . VAL A 1 252 ? 119.862 109.640 93.691  1.00 63.73  ? 243 VAL A O      1 
ATOM   2652 C CB     . VAL A 1 252 ? 121.665 112.309 93.086  1.00 63.73  ? 243 VAL A CB     1 
ATOM   2653 C CG1    . VAL A 1 252 ? 122.551 111.179 93.581  1.00 63.73  ? 243 VAL A CG1    1 
ATOM   2654 C CG2    . VAL A 1 252 ? 122.331 113.044 91.937  1.00 63.73  ? 243 VAL A CG2    1 
ATOM   2655 H H      . VAL A 1 252 ? 119.674 113.636 92.533  1.00 63.73  ? 243 VAL A H      1 
ATOM   2656 H HA     . VAL A 1 252 ? 120.435 111.221 91.854  1.00 63.73  ? 243 VAL A HA     1 
ATOM   2657 H HB     . VAL A 1 252 ? 121.539 112.936 93.815  1.00 63.73  ? 243 VAL A HB     1 
ATOM   2658 H HG11   . VAL A 1 252 ? 122.275 110.926 94.476  1.00 63.73  ? 243 VAL A HG11   1 
ATOM   2659 H HG12   . VAL A 1 252 ? 123.471 111.485 93.594  1.00 63.73  ? 243 VAL A HG12   1 
ATOM   2660 H HG13   . VAL A 1 252 ? 122.463 110.423 92.979  1.00 63.73  ? 243 VAL A HG13   1 
ATOM   2661 H HG21   . VAL A 1 252 ? 122.482 112.421 91.209  1.00 63.73  ? 243 VAL A HG21   1 
ATOM   2662 H HG22   . VAL A 1 252 ? 123.177 113.408 92.243  1.00 63.73  ? 243 VAL A HG22   1 
ATOM   2663 H HG23   . VAL A 1 252 ? 121.750 113.763 91.642  1.00 63.73  ? 243 VAL A HG23   1 
ATOM   2664 N N      . LEU A 1 253 ? 118.983 111.451 94.683  1.00 62.52  ? 244 LEU A N      1 
ATOM   2665 C CA     . LEU A 1 253 ? 118.289 110.648 95.682  1.00 62.52  ? 244 LEU A CA     1 
ATOM   2666 C C      . LEU A 1 253 ? 117.245 109.755 95.028  1.00 62.52  ? 244 LEU A C      1 
ATOM   2667 O O      . LEU A 1 253 ? 117.120 108.575 95.373  1.00 62.52  ? 244 LEU A O      1 
ATOM   2668 C CB     . LEU A 1 253 ? 117.641 111.562 96.720  1.00 62.52  ? 244 LEU A CB     1 
ATOM   2669 C CG     . LEU A 1 253 ? 116.801 110.897 97.807  1.00 62.52  ? 244 LEU A CG     1 
ATOM   2670 C CD1    . LEU A 1 253 ? 117.622 109.891 98.590  1.00 62.52  ? 244 LEU A CD1    1 
ATOM   2671 C CD2    . LEU A 1 253 ? 116.232 111.953 98.732  1.00 62.52  ? 244 LEU A CD2    1 
ATOM   2672 H H      . LEU A 1 253 ? 118.892 112.301 94.778  1.00 62.52  ? 244 LEU A H      1 
ATOM   2673 H HA     . LEU A 1 253 ? 118.931 110.080 96.135  1.00 62.52  ? 244 LEU A HA     1 
ATOM   2674 H HB2    . LEU A 1 253 ? 118.346 112.056 97.167  1.00 62.52  ? 244 LEU A HB2    1 
ATOM   2675 H HB3    . LEU A 1 253 ? 117.062 112.184 96.254  1.00 62.52  ? 244 LEU A HB3    1 
ATOM   2676 H HG     . LEU A 1 253 ? 116.059 110.427 97.396  1.00 62.52  ? 244 LEU A HG     1 
ATOM   2677 H HD11   . LEU A 1 253 ? 117.086 109.549 99.323  1.00 62.52  ? 244 LEU A HD11   1 
ATOM   2678 H HD12   . LEU A 1 253 ? 117.878 109.164 98.001  1.00 62.52  ? 244 LEU A HD12   1 
ATOM   2679 H HD13   . LEU A 1 253 ? 118.414 110.332 98.937  1.00 62.52  ? 244 LEU A HD13   1 
ATOM   2680 H HD21   . LEU A 1 253 ? 115.803 111.515 99.483  1.00 62.52  ? 244 LEU A HD21   1 
ATOM   2681 H HD22   . LEU A 1 253 ? 115.584 112.484 98.243  1.00 62.52  ? 244 LEU A HD22   1 
ATOM   2682 H HD23   . LEU A 1 253 ? 116.954 112.518 99.047  1.00 62.52  ? 244 LEU A HD23   1 
ATOM   2683 N N      . PHE A 1 254 ? 116.490 110.303 94.077  1.00 62.58  ? 245 PHE A N      1 
ATOM   2684 C CA     . PHE A 1 254 ? 115.502 109.505 93.361  1.00 62.58  ? 245 PHE A CA     1 
ATOM   2685 C C      . PHE A 1 254 ? 116.164 108.348 92.632  1.00 62.58  ? 245 PHE A C      1 
ATOM   2686 O O      . PHE A 1 254 ? 115.657 107.222 92.649  1.00 62.58  ? 245 PHE A O      1 
ATOM   2687 C CB     . PHE A 1 254 ? 114.735 110.390 92.379  1.00 62.58  ? 245 PHE A CB     1 
ATOM   2688 C CG     . PHE A 1 254 ? 114.019 109.628 91.299  1.00 62.58  ? 245 PHE A CG     1 
ATOM   2689 C CD1    . PHE A 1 254 ? 114.664 109.297 90.121  1.00 62.58  ? 245 PHE A CD1    1 
ATOM   2690 C CD2    . PHE A 1 254 ? 112.699 109.261 91.453  1.00 62.58  ? 245 PHE A CD2    1 
ATOM   2691 C CE1    . PHE A 1 254 ? 114.008 108.604 89.127  1.00 62.58  ? 245 PHE A CE1    1 
ATOM   2692 C CE2    . PHE A 1 254 ? 112.039 108.571 90.458  1.00 62.58  ? 245 PHE A CE2    1 
ATOM   2693 C CZ     . PHE A 1 254 ? 112.695 108.242 89.296  1.00 62.58  ? 245 PHE A CZ     1 
ATOM   2694 H H      . PHE A 1 254 ? 116.530 111.126 93.830  1.00 62.58  ? 245 PHE A H      1 
ATOM   2695 H HA     . PHE A 1 254 ? 114.868 109.139 93.997  1.00 62.58  ? 245 PHE A HA     1 
ATOM   2696 H HB2    . PHE A 1 254 ? 114.072 110.900 92.868  1.00 62.58  ? 245 PHE A HB2    1 
ATOM   2697 H HB3    . PHE A 1 254 ? 115.361 110.993 91.949  1.00 62.58  ? 245 PHE A HB3    1 
ATOM   2698 H HD1    . PHE A 1 254 ? 115.554 109.539 90.001  1.00 62.58  ? 245 PHE A HD1    1 
ATOM   2699 H HD2    . PHE A 1 254 ? 112.249 109.480 92.237  1.00 62.58  ? 245 PHE A HD2    1 
ATOM   2700 H HE1    . PHE A 1 254 ? 114.454 108.384 88.341  1.00 62.58  ? 245 PHE A HE1    1 
ATOM   2701 H HE2    . PHE A 1 254 ? 111.150 108.325 90.575  1.00 62.58  ? 245 PHE A HE2    1 
ATOM   2702 H HZ     . PHE A 1 254 ? 112.250 107.775 88.626  1.00 62.58  ? 245 PHE A HZ     1 
ATOM   2703 N N      . LEU A 1 255 ? 117.295 108.607 91.976  1.00 63.02  ? 246 LEU A N      1 
ATOM   2704 C CA     . LEU A 1 255 ? 117.984 107.526 91.277  1.00 63.02  ? 246 LEU A CA     1 
ATOM   2705 C C      . LEU A 1 255 ? 118.491 106.468 92.251  1.00 63.02  ? 246 LEU A C      1 
ATOM   2706 O O      . LEU A 1 255 ? 118.348 105.265 92.000  1.00 63.02  ? 246 LEU A O      1 
ATOM   2707 C CB     . LEU A 1 255 ? 119.137 108.082 90.443  1.00 63.02  ? 246 LEU A CB     1 
ATOM   2708 C CG     . LEU A 1 255 ? 118.745 108.779 89.139  1.00 63.02  ? 246 LEU A CG     1 
ATOM   2709 C CD1    . LEU A 1 255 ? 119.983 109.279 88.416  1.00 63.02  ? 246 LEU A CD1    1 
ATOM   2710 C CD2    . LEU A 1 255 ? 117.940 107.853 88.240  1.00 63.02  ? 246 LEU A CD2    1 
ATOM   2711 H H      . LEU A 1 255 ? 117.675 109.376 91.922  1.00 63.02  ? 246 LEU A H      1 
ATOM   2712 H HA     . LEU A 1 255 ? 117.356 107.092 90.680  1.00 63.02  ? 246 LEU A HA     1 
ATOM   2713 H HB2    . LEU A 1 255 ? 119.619 108.728 90.983  1.00 63.02  ? 246 LEU A HB2    1 
ATOM   2714 H HB3    . LEU A 1 255 ? 119.729 107.349 90.213  1.00 63.02  ? 246 LEU A HB3    1 
ATOM   2715 H HG     . LEU A 1 255 ? 118.191 109.548 89.348  1.00 63.02  ? 246 LEU A HG     1 
ATOM   2716 H HD11   . LEU A 1 255 ? 119.712 109.726 87.599  1.00 63.02  ? 246 LEU A HD11   1 
ATOM   2717 H HD12   . LEU A 1 255 ? 120.456 109.900 88.992  1.00 63.02  ? 246 LEU A HD12   1 
ATOM   2718 H HD13   . LEU A 1 255 ? 120.552 108.522 88.206  1.00 63.02  ? 246 LEU A HD13   1 
ATOM   2719 H HD21   . LEU A 1 255 ? 117.934 108.213 87.340  1.00 63.02  ? 246 LEU A HD21   1 
ATOM   2720 H HD22   . LEU A 1 255 ? 118.354 106.975 88.242  1.00 63.02  ? 246 LEU A HD22   1 
ATOM   2721 H HD23   . LEU A 1 255 ? 117.034 107.792 88.578  1.00 63.02  ? 246 LEU A HD23   1 
ATOM   2722 N N      . ALA A 1 256 ? 119.077 106.892 93.373  1.00 62.72  ? 247 ALA A N      1 
ATOM   2723 C CA     . ALA A 1 256 ? 119.625 105.937 94.330  1.00 62.72  ? 247 ALA A CA     1 
ATOM   2724 C C      . ALA A 1 256 ? 118.529 105.154 95.037  1.00 62.72  ? 247 ALA A C      1 
ATOM   2725 O O      . ALA A 1 256 ? 118.783 104.057 95.547  1.00 62.72  ? 247 ALA A O      1 
ATOM   2726 C CB     . ALA A 1 256 ? 120.496 106.661 95.356  1.00 62.72  ? 247 ALA A CB     1 
ATOM   2727 H H      . ALA A 1 256 ? 119.169 107.717 93.598  1.00 62.72  ? 247 ALA A H      1 
ATOM   2728 H HA     . ALA A 1 256 ? 120.187 105.304 93.856  1.00 62.72  ? 247 ALA A HA     1 
ATOM   2729 H HB1    . ALA A 1 256 ? 121.223 107.108 94.894  1.00 62.72  ? 247 ALA A HB1    1 
ATOM   2730 H HB2    . ALA A 1 256 ? 119.952 107.313 95.826  1.00 62.72  ? 247 ALA A HB2    1 
ATOM   2731 H HB3    . ALA A 1 256 ? 120.851 106.013 95.984  1.00 62.72  ? 247 ALA A HB3    1 
ATOM   2732 N N      . GLY A 1 257 ? 117.311 105.691 95.077  1.00 62.66  ? 248 GLY A N      1 
ATOM   2733 C CA     . GLY A 1 257 ? 116.233 105.000 95.757  1.00 62.66  ? 248 GLY A CA     1 
ATOM   2734 C C      . GLY A 1 257 ? 115.962 103.613 95.221  1.00 62.66  ? 248 GLY A C      1 
ATOM   2735 O O      . GLY A 1 257 ? 115.352 102.798 95.918  1.00 62.66  ? 248 GLY A O      1 
ATOM   2736 H H      . GLY A 1 257 ? 117.090 106.443 94.725  1.00 62.66  ? 248 GLY A H      1 
ATOM   2737 H HA2    . GLY A 1 257 ? 116.448 104.924 96.700  1.00 62.66  ? 248 GLY A HA2    1 
ATOM   2738 H HA3    . GLY A 1 257 ? 115.419 105.520 95.673  1.00 62.66  ? 248 GLY A HA3    1 
ATOM   2739 N N      . PHE A 1 258 ? 116.400 103.321 93.997  1.00 63.66  ? 249 PHE A N      1 
ATOM   2740 C CA     . PHE A 1 258 ? 116.170 102.002 93.423  1.00 63.66  ? 249 PHE A CA     1 
ATOM   2741 C C      . PHE A 1 258 ? 117.048 100.919 94.038  1.00 63.66  ? 249 PHE A C      1 
ATOM   2742 O O      . PHE A 1 258 ? 116.813 99.736  93.771  1.00 63.66  ? 249 PHE A O      1 
ATOM   2743 C CB     . PHE A 1 258 ? 116.393 102.047 91.914  1.00 63.66  ? 249 PHE A CB     1 
ATOM   2744 C CG     . PHE A 1 258 ? 115.228 102.597 91.150  1.00 63.66  ? 249 PHE A CG     1 
ATOM   2745 C CD1    . PHE A 1 258 ? 114.241 101.756 90.672  1.00 63.66  ? 249 PHE A CD1    1 
ATOM   2746 C CD2    . PHE A 1 258 ? 115.118 103.953 90.913  1.00 63.66  ? 249 PHE A CD2    1 
ATOM   2747 C CE1    . PHE A 1 258 ? 113.167 102.258 89.968  1.00 63.66  ? 249 PHE A CE1    1 
ATOM   2748 C CE2    . PHE A 1 258 ? 114.045 104.461 90.210  1.00 63.66  ? 249 PHE A CE2    1 
ATOM   2749 C CZ     . PHE A 1 258 ? 113.068 103.612 89.738  1.00 63.66  ? 249 PHE A CZ     1 
ATOM   2750 H H      . PHE A 1 258 ? 116.827 103.864 93.484  1.00 63.66  ? 249 PHE A H      1 
ATOM   2751 H HA     . PHE A 1 258 ? 115.245 101.754 93.577  1.00 63.66  ? 249 PHE A HA     1 
ATOM   2752 H HB2    . PHE A 1 258 ? 117.162 102.607 91.727  1.00 63.66  ? 249 PHE A HB2    1 
ATOM   2753 H HB3    . PHE A 1 258 ? 116.557 101.145 91.595  1.00 63.66  ? 249 PHE A HB3    1 
ATOM   2754 H HD1    . PHE A 1 258 ? 114.303 100.841 90.824  1.00 63.66  ? 249 PHE A HD1    1 
ATOM   2755 H HD2    . PHE A 1 258 ? 115.774 104.531 91.230  1.00 63.66  ? 249 PHE A HD2    1 
ATOM   2756 H HE1    . PHE A 1 258 ? 112.509 101.683 89.651  1.00 63.66  ? 249 PHE A HE1    1 
ATOM   2757 H HE2    . PHE A 1 258 ? 113.980 105.375 90.056  1.00 63.66  ? 249 PHE A HE2    1 
ATOM   2758 H HZ     . PHE A 1 258 ? 112.344 103.953 89.264  1.00 63.66  ? 249 PHE A HZ     1 
ATOM   2759 N N      . THR A 1 259 ? 118.048 101.282 94.845  1.00 62.99  ? 250 THR A N      1 
ATOM   2760 C CA     . THR A 1 259 ? 118.882 100.263 95.475  1.00 62.99  ? 250 THR A CA     1 
ATOM   2761 C C      . THR A 1 259 ? 118.104 99.483  96.527  1.00 62.99  ? 250 THR A C      1 
ATOM   2762 O O      . THR A 1 259 ? 118.227 98.257  96.612  1.00 62.99  ? 250 THR A O      1 
ATOM   2763 C CB     . THR A 1 259 ? 120.119 100.905 96.099  1.00 62.99  ? 250 THR A CB     1 
ATOM   2764 O OG1    . THR A 1 259 ? 119.716 101.827 97.118  1.00 62.99  ? 250 THR A OG1    1 
ATOM   2765 C CG2    . THR A 1 259 ? 120.929 101.640 95.044  1.00 62.99  ? 250 THR A CG2    1 
ATOM   2766 H H      . THR A 1 259 ? 118.258 102.092 95.041  1.00 62.99  ? 250 THR A H      1 
ATOM   2767 H HA     . THR A 1 259 ? 119.181 99.637  94.797  1.00 62.99  ? 250 THR A HA     1 
ATOM   2768 H HB     . THR A 1 259 ? 120.678 100.216 96.490  1.00 62.99  ? 250 THR A HB     1 
ATOM   2769 H HG1    . THR A 1 259 ? 119.236 102.431 96.785  1.00 62.99  ? 250 THR A HG1    1 
ATOM   2770 H HG21   . THR A 1 259 ? 121.738 101.999 95.439  1.00 62.99  ? 250 THR A HG21   1 
ATOM   2771 H HG22   . THR A 1 259 ? 120.408 102.369 94.673  1.00 62.99  ? 250 THR A HG22   1 
ATOM   2772 H HG23   . THR A 1 259 ? 121.171 101.030 94.329  1.00 62.99  ? 250 THR A HG23   1 
ATOM   2773 N N      . TYR A 1 260 ? 117.301 100.173 97.335  1.00 60.52  ? 251 TYR A N      1 
ATOM   2774 C CA     . TYR A 1 260 ? 116.514 99.509  98.367  1.00 60.52  ? 251 TYR A CA     1 
ATOM   2775 C C      . TYR A 1 260 ? 115.742 98.342  97.777  1.00 60.52  ? 251 TYR A C      1 
ATOM   2776 O O      . TYR A 1 260 ? 114.890 98.526  96.905  1.00 60.52  ? 251 TYR A O      1 
ATOM   2777 C CB     . TYR A 1 260 ? 115.536 100.493 99.009  1.00 60.52  ? 251 TYR A CB     1 
ATOM   2778 C CG     . TYR A 1 260 ? 116.163 101.649 99.749  1.00 60.52  ? 251 TYR A CG     1 
ATOM   2779 C CD1    . TYR A 1 260 ? 116.876 101.448 100.916 1.00 60.52  ? 251 TYR A CD1    1 
ATOM   2780 C CD2    . TYR A 1 260 ? 116.006 102.947 99.296  1.00 60.52  ? 251 TYR A CD2    1 
ATOM   2781 C CE1    . TYR A 1 260 ? 117.434 102.505 101.599 1.00 60.52  ? 251 TYR A CE1    1 
ATOM   2782 C CE2    . TYR A 1 260 ? 116.559 104.010 99.971  1.00 60.52  ? 251 TYR A CE2    1 
ATOM   2783 C CZ     . TYR A 1 260 ? 117.271 103.785 101.121 1.00 60.52  ? 251 TYR A CZ     1 
ATOM   2784 O OH     . TYR A 1 260 ? 117.823 104.849 101.795 1.00 60.52  ? 251 TYR A OH     1 
ATOM   2785 H H      . TYR A 1 260 ? 117.194 101.026 97.304  1.00 60.52  ? 251 TYR A H      1 
ATOM   2786 H HA     . TYR A 1 260 ? 117.106 99.169  99.056  1.00 60.52  ? 251 TYR A HA     1 
ATOM   2787 H HB2    . TYR A 1 260 ? 114.975 100.865 98.311  1.00 60.52  ? 251 TYR A HB2    1 
ATOM   2788 H HB3    . TYR A 1 260 ? 114.984 100.008 99.642  1.00 60.52  ? 251 TYR A HB3    1 
ATOM   2789 H HD1    . TYR A 1 260 ? 116.988 100.584 101.240 1.00 60.52  ? 251 TYR A HD1    1 
ATOM   2790 H HD2    . TYR A 1 260 ? 115.524 103.104 98.516  1.00 60.52  ? 251 TYR A HD2    1 
ATOM   2791 H HE1    . TYR A 1 260 ? 117.918 102.356 102.379 1.00 60.52  ? 251 TYR A HE1    1 
ATOM   2792 H HE2    . TYR A 1 260 ? 116.450 104.876 99.649  1.00 60.52  ? 251 TYR A HE2    1 
ATOM   2793 H HH     . TYR A 1 260 ? 117.647 105.565 101.393 1.00 60.52  ? 251 TYR A HH     1 
ATOM   2794 N N      . ARG A 1 261 ? 116.044 97.142  98.243  1.00 65.49  ? 252 ARG A N      1 
ATOM   2795 C CA     . ARG A 1 261 ? 115.267 95.976  97.851  1.00 65.49  ? 252 ARG A CA     1 
ATOM   2796 C C      . ARG A 1 261 ? 115.434 94.881  98.896  1.00 65.49  ? 252 ARG A C      1 
ATOM   2797 O O      . ARG A 1 261 ? 116.461 94.191  98.905  1.00 65.49  ? 252 ARG A O      1 
ATOM   2798 C CB     . ARG A 1 261 ? 115.692 95.476  96.472  1.00 65.49  ? 252 ARG A CB     1 
ATOM   2799 C CG     . ARG A 1 261 ? 114.775 94.402  95.915  1.00 65.49  ? 252 ARG A CG     1 
ATOM   2800 C CD     . ARG A 1 261 ? 114.930 94.253  94.412  1.00 65.49  ? 252 ARG A CD     1 
ATOM   2801 N NE     . ARG A 1 261 ? 114.005 93.266  93.870  1.00 65.49  ? 252 ARG A NE     1 
ATOM   2802 C CZ     . ARG A 1 261 ? 113.847 93.015  92.577  1.00 65.49  ? 252 ARG A CZ     1 
ATOM   2803 N NH1    . ARG A 1 261 ? 114.536 93.668  91.656  1.00 65.49  ? 252 ARG A NH1    1 
ATOM   2804 N NH2    . ARG A 1 261 ? 112.973 92.087  92.199  1.00 65.49  ? 252 ARG A NH2    1 
ATOM   2805 H H      . ARG A 1 261 ? 116.690 96.974  98.786  1.00 65.49  ? 252 ARG A H      1 
ATOM   2806 H HA     . ARG A 1 261 ? 114.332 96.223  97.796  1.00 65.49  ? 252 ARG A HA     1 
ATOM   2807 H HB2    . ARG A 1 261 ? 115.689 96.221  95.852  1.00 65.49  ? 252 ARG A HB2    1 
ATOM   2808 H HB3    . ARG A 1 261 ? 116.585 95.102  96.534  1.00 65.49  ? 252 ARG A HB3    1 
ATOM   2809 H HG2    . ARG A 1 261 ? 114.992 93.551  96.327  1.00 65.49  ? 252 ARG A HG2    1 
ATOM   2810 H HG3    . ARG A 1 261 ? 113.853 94.639  96.103  1.00 65.49  ? 252 ARG A HG3    1 
ATOM   2811 H HD2    . ARG A 1 261 ? 114.747 95.106  93.987  1.00 65.49  ? 252 ARG A HD2    1 
ATOM   2812 H HD3    . ARG A 1 261 ? 115.833 93.965  94.211  1.00 65.49  ? 252 ARG A HD3    1 
ATOM   2813 H HE     . ARG A 1 261 ? 113.573 92.774  94.428  1.00 65.49  ? 252 ARG A HE     1 
ATOM   2814 H HH11   . ARG A 1 261 ? 115.104 94.271  91.887  1.00 65.49  ? 252 ARG A HH11   1 
ATOM   2815 H HH12   . ARG A 1 261 ? 114.416 93.489  90.823  1.00 65.49  ? 252 ARG A HH12   1 
ATOM   2816 H HH21   . ARG A 1 261 ? 112.519 91.657  92.790  1.00 65.49  ? 252 ARG A HH21   1 
ATOM   2817 H HH22   . ARG A 1 261 ? 112.861 91.916  91.363  1.00 65.49  ? 252 ARG A HH22   1 
ATOM   2818 N N      . PRO A 1 262 ? 114.467 94.691  99.793  1.00 67.34  ? 253 PRO A N      1 
ATOM   2819 C CA     . PRO A 1 262 ? 114.627 93.670  100.832 1.00 67.34  ? 253 PRO A CA     1 
ATOM   2820 C C      . PRO A 1 262 ? 114.956 92.314  100.226 1.00 67.34  ? 253 PRO A C      1 
ATOM   2821 O O      . PRO A 1 262 ? 114.377 91.905  99.218  1.00 67.34  ? 253 PRO A O      1 
ATOM   2822 C CB     . PRO A 1 262 ? 113.266 93.665  101.535 1.00 67.34  ? 253 PRO A CB     1 
ATOM   2823 C CG     . PRO A 1 262 ? 112.730 95.030  101.314 1.00 67.34  ? 253 PRO A CG     1 
ATOM   2824 C CD     . PRO A 1 262 ? 113.213 95.447  99.955  1.00 67.34  ? 253 PRO A CD     1 
ATOM   2825 H HA     . PRO A 1 262 ? 115.320 93.925  101.461 1.00 67.34  ? 253 PRO A HA     1 
ATOM   2826 H HB2    . PRO A 1 262 ? 112.690 92.997  101.130 1.00 67.34  ? 253 PRO A HB2    1 
ATOM   2827 H HB3    . PRO A 1 262 ? 113.386 93.490  102.482 1.00 67.34  ? 253 PRO A HB3    1 
ATOM   2828 H HG2    . PRO A 1 262 ? 111.761 95.005  101.338 1.00 67.34  ? 253 PRO A HG2    1 
ATOM   2829 H HG3    . PRO A 1 262 ? 113.073 95.627  101.996 1.00 67.34  ? 253 PRO A HG3    1 
ATOM   2830 H HD2    . PRO A 1 262 ? 112.572 95.189  99.274  1.00 67.34  ? 253 PRO A HD2    1 
ATOM   2831 H HD3    . PRO A 1 262 ? 113.388 96.401  99.936  1.00 67.34  ? 253 PRO A HD3    1 
ATOM   2832 N N      . LEU A 1 263 ? 115.901 91.622  100.849 1.00 72.18  ? 254 LEU A N      1 
ATOM   2833 C CA     . LEU A 1 263 ? 116.394 90.359  100.324 1.00 72.18  ? 254 LEU A CA     1 
ATOM   2834 C C      . LEU A 1 263 ? 116.844 89.444  101.456 1.00 72.18  ? 254 LEU A C      1 
ATOM   2835 O O      . LEU A 1 263 ? 116.963 89.874  102.603 1.00 72.18  ? 254 LEU A O      1 
ATOM   2836 C CB     . LEU A 1 263 ? 117.547 90.608  99.349  1.00 72.18  ? 254 LEU A CB     1 
ATOM   2837 C CG     . LEU A 1 263 ? 118.200 89.374  98.724  1.00 72.18  ? 254 LEU A CG     1 
ATOM   2838 C CD1    . LEU A 1 263 ? 117.179 88.550  97.959  1.00 72.18  ? 254 LEU A CD1    1 
ATOM   2839 C CD2    . LEU A 1 263 ? 119.348 89.786  97.816  1.00 72.18  ? 254 LEU A CD2    1 
ATOM   2840 H H      . LEU A 1 263 ? 116.275 91.865  101.584 1.00 72.18  ? 254 LEU A H      1 
ATOM   2841 H HA     . LEU A 1 263 ? 115.679 89.914  99.842  1.00 72.18  ? 254 LEU A HA     1 
ATOM   2842 H HB2    . LEU A 1 263 ? 117.215 91.156  98.621  1.00 72.18  ? 254 LEU A HB2    1 
ATOM   2843 H HB3    . LEU A 1 263 ? 118.243 91.091  99.822  1.00 72.18  ? 254 LEU A HB3    1 
ATOM   2844 H HG     . LEU A 1 263 ? 118.565 88.817  99.430  1.00 72.18  ? 254 LEU A HG     1 
ATOM   2845 H HD11   . LEU A 1 263 ? 116.536 88.182  98.584  1.00 72.18  ? 254 LEU A HD11   1 
ATOM   2846 H HD12   . LEU A 1 263 ? 117.638 87.832  97.495  1.00 72.18  ? 254 LEU A HD12   1 
ATOM   2847 H HD13   . LEU A 1 263 ? 116.729 89.123  97.318  1.00 72.18  ? 254 LEU A HD13   1 
ATOM   2848 H HD21   . LEU A 1 263 ? 120.002 90.277  98.338  1.00 72.18  ? 254 LEU A HD21   1 
ATOM   2849 H HD22   . LEU A 1 263 ? 119.755 88.990  97.440  1.00 72.18  ? 254 LEU A HD22   1 
ATOM   2850 H HD23   . LEU A 1 263 ? 119.002 90.349  97.106  1.00 72.18  ? 254 LEU A HD23   1 
ATOM   2851 N N      . ASN A 1 293 ? 97.692  101.983 121.527 1.00 70.70  ? 284 ASN A N      1 
ATOM   2852 C CA     . ASN A 1 293 ? 99.075  102.440 121.465 1.00 70.70  ? 284 ASN A CA     1 
ATOM   2853 C C      . ASN A 1 293 ? 99.290  103.662 122.354 1.00 70.70  ? 284 ASN A C      1 
ATOM   2854 O O      . ASN A 1 293 ? 100.379 104.231 122.382 1.00 70.70  ? 284 ASN A O      1 
ATOM   2855 C CB     . ASN A 1 293 ? 99.465  102.768 120.021 1.00 70.70  ? 284 ASN A CB     1 
ATOM   2856 C CG     . ASN A 1 293 ? 99.189  101.621 119.067 1.00 70.70  ? 284 ASN A CG     1 
ATOM   2857 O OD1    . ASN A 1 293 ? 99.207  100.454 119.457 1.00 70.70  ? 284 ASN A OD1    1 
ATOM   2858 N ND2    . ASN A 1 293 ? 98.933  101.950 117.806 1.00 70.70  ? 284 ASN A ND2    1 
ATOM   2859 H H      . ASN A 1 293 ? 97.549  101.242 121.114 1.00 70.70  ? 284 ASN A H      1 
ATOM   2860 H HA     . ASN A 1 293 ? 99.657  101.731 121.781 1.00 70.70  ? 284 ASN A HA     1 
ATOM   2861 H HB2    . ASN A 1 293 ? 98.955  103.537 119.722 1.00 70.70  ? 284 ASN A HB2    1 
ATOM   2862 H HB3    . ASN A 1 293 ? 100.414 102.965 119.988 1.00 70.70  ? 284 ASN A HB3    1 
ATOM   2863 H HD21   . ASN A 1 293 ? 98.929  102.777 117.570 1.00 70.70  ? 284 ASN A HD21   1 
ATOM   2864 H HD22   . ASN A 1 293 ? 98.770  101.337 117.226 1.00 70.70  ? 284 ASN A HD22   1 
ATOM   2865 N N      . PHE A 1 294 ? 98.247  104.066 123.074 1.00 70.45  ? 285 PHE A N      1 
ATOM   2866 C CA     . PHE A 1 294 ? 98.318  105.206 123.976 1.00 70.45  ? 285 PHE A CA     1 
ATOM   2867 C C      . PHE A 1 294 ? 98.640  104.805 125.412 1.00 70.45  ? 285 PHE A C      1 
ATOM   2868 O O      . PHE A 1 294 ? 98.731  105.680 126.279 1.00 70.45  ? 285 PHE A O      1 
ATOM   2869 C CB     . PHE A 1 294 ? 96.994  105.979 123.931 1.00 70.45  ? 285 PHE A CB     1 
ATOM   2870 C CG     . PHE A 1 294 ? 97.011  107.269 124.705 1.00 70.45  ? 285 PHE A CG     1 
ATOM   2871 C CD1    . PHE A 1 294 ? 97.697  108.371 124.228 1.00 70.45  ? 285 PHE A CD1    1 
ATOM   2872 C CD2    . PHE A 1 294 ? 96.329  107.380 125.906 1.00 70.45  ? 285 PHE A CD2    1 
ATOM   2873 C CE1    . PHE A 1 294 ? 97.711  109.557 124.938 1.00 70.45  ? 285 PHE A CE1    1 
ATOM   2874 C CE2    . PHE A 1 294 ? 96.341  108.563 126.618 1.00 70.45  ? 285 PHE A CE2    1 
ATOM   2875 C CZ     . PHE A 1 294 ? 97.033  109.653 126.133 1.00 70.45  ? 285 PHE A CZ     1 
ATOM   2876 H H      . PHE A 1 294 ? 97.474  103.691 123.059 1.00 70.45  ? 285 PHE A H      1 
ATOM   2877 H HA     . PHE A 1 294 ? 99.020  105.802 123.671 1.00 70.45  ? 285 PHE A HA     1 
ATOM   2878 H HB2    . PHE A 1 294 ? 96.789  106.192 123.007 1.00 70.45  ? 285 PHE A HB2    1 
ATOM   2879 H HB3    . PHE A 1 294 ? 96.293  105.420 124.301 1.00 70.45  ? 285 PHE A HB3    1 
ATOM   2880 H HD1    . PHE A 1 294 ? 98.158  108.312 123.423 1.00 70.45  ? 285 PHE A HD1    1 
ATOM   2881 H HD2    . PHE A 1 294 ? 95.862  106.648 126.238 1.00 70.45  ? 285 PHE A HD2    1 
ATOM   2882 H HE1    . PHE A 1 294 ? 98.178  110.291 124.609 1.00 70.45  ? 285 PHE A HE1    1 
ATOM   2883 H HE2    . PHE A 1 294 ? 95.881  108.625 127.425 1.00 70.45  ? 285 PHE A HE2    1 
ATOM   2884 H HZ     . PHE A 1 294 ? 97.040  110.450 126.611 1.00 70.45  ? 285 PHE A HZ     1 
ATOM   2885 N N      . ALA A 1 295 ? 98.834  103.513 125.682 1.00 69.04  ? 286 ALA A N      1 
ATOM   2886 C CA     . ALA A 1 295 ? 99.081  103.049 127.043 1.00 69.04  ? 286 ALA A CA     1 
ATOM   2887 C C      . ALA A 1 295 ? 100.484 103.372 127.541 1.00 69.04  ? 286 ALA A C      1 
ATOM   2888 O O      . ALA A 1 295 ? 100.776 103.119 128.714 1.00 69.04  ? 286 ALA A O      1 
ATOM   2889 C CB     . ALA A 1 295 ? 98.845  101.540 127.128 1.00 69.04  ? 286 ALA A CB     1 
ATOM   2890 H H      . ALA A 1 295 ? 98.825  102.886 125.094 1.00 69.04  ? 286 ALA A H      1 
ATOM   2891 H HA     . ALA A 1 295 ? 98.450  103.482 127.639 1.00 69.04  ? 286 ALA A HA     1 
ATOM   2892 H HB1    . ALA A 1 295 ? 97.926  101.351 126.881 1.00 69.04  ? 286 ALA A HB1    1 
ATOM   2893 H HB2    . ALA A 1 295 ? 99.010  101.246 128.037 1.00 69.04  ? 286 ALA A HB2    1 
ATOM   2894 H HB3    . ALA A 1 295 ? 99.451  101.091 126.519 1.00 69.04  ? 286 ALA A HB3    1 
ATOM   2895 N N      . ILE A 1 296 ? 101.354 103.919 126.691 1.00 69.00  ? 287 ILE A N      1 
ATOM   2896 C CA     . ILE A 1 296 ? 102.744 104.135 127.084 1.00 69.00  ? 287 ILE A CA     1 
ATOM   2897 C C      . ILE A 1 296 ? 102.833 105.107 128.253 1.00 69.00  ? 287 ILE A C      1 
ATOM   2898 O O      . ILE A 1 296 ? 103.701 104.973 129.122 1.00 69.00  ? 287 ILE A O      1 
ATOM   2899 C CB     . ILE A 1 296 ? 103.567 104.634 125.885 1.00 69.00  ? 287 ILE A CB     1 
ATOM   2900 C CG1    . ILE A 1 296 ? 105.041 104.744 126.268 1.00 69.00  ? 287 ILE A CG1    1 
ATOM   2901 C CG2    . ILE A 1 296 ? 103.058 105.985 125.421 1.00 69.00  ? 287 ILE A CG2    1 
ATOM   2902 C CD1    . ILE A 1 296 ? 105.946 105.082 125.108 1.00 69.00  ? 287 ILE A CD1    1 
ATOM   2903 H H      . ILE A 1 296 ? 101.167 104.170 125.890 1.00 69.00  ? 287 ILE A H      1 
ATOM   2904 H HA     . ILE A 1 296 ? 103.122 103.290 127.372 1.00 69.00  ? 287 ILE A HA     1 
ATOM   2905 H HB     . ILE A 1 296 ? 103.479 103.999 125.157 1.00 69.00  ? 287 ILE A HB     1 
ATOM   2906 H HG12   . ILE A 1 296 ? 105.145 105.442 126.934 1.00 69.00  ? 287 ILE A HG12   1 
ATOM   2907 H HG13   . ILE A 1 296 ? 105.333 103.895 126.635 1.00 69.00  ? 287 ILE A HG13   1 
ATOM   2908 H HG21   . ILE A 1 296 ? 103.433 106.180 124.548 1.00 69.00  ? 287 ILE A HG21   1 
ATOM   2909 H HG22   . ILE A 1 296 ? 102.091 105.959 125.363 1.00 69.00  ? 287 ILE A HG22   1 
ATOM   2910 H HG23   . ILE A 1 296 ? 103.332 106.663 126.058 1.00 69.00  ? 287 ILE A HG23   1 
ATOM   2911 H HD11   . ILE A 1 296 ? 106.854 105.181 125.436 1.00 69.00  ? 287 ILE A HD11   1 
ATOM   2912 H HD12   . ILE A 1 296 ? 105.906 104.361 124.460 1.00 69.00  ? 287 ILE A HD12   1 
ATOM   2913 H HD13   . ILE A 1 296 ? 105.651 105.910 124.699 1.00 69.00  ? 287 ILE A HD13   1 
ATOM   2914 N N      . PHE A 1 297 ? 101.944 106.101 128.295 1.00 69.00  ? 288 PHE A N      1 
ATOM   2915 C CA     . PHE A 1 297 ? 102.078 107.183 129.264 1.00 69.00  ? 288 PHE A CA     1 
ATOM   2916 C C      . PHE A 1 297 ? 102.008 106.709 130.709 1.00 69.00  ? 288 PHE A C      1 
ATOM   2917 O O      . PHE A 1 297 ? 102.423 107.454 131.602 1.00 69.00  ? 288 PHE A O      1 
ATOM   2918 C CB     . PHE A 1 297 ? 100.993 108.240 129.034 1.00 69.00  ? 288 PHE A CB     1 
ATOM   2919 C CG     . PHE A 1 297 ? 101.326 109.251 127.964 1.00 69.00  ? 288 PHE A CG     1 
ATOM   2920 C CD1    . PHE A 1 297 ? 102.606 109.767 127.838 1.00 69.00  ? 288 PHE A CD1    1 
ATOM   2921 C CD2    . PHE A 1 297 ? 100.346 109.696 127.093 1.00 69.00  ? 288 PHE A CD2    1 
ATOM   2922 C CE1    . PHE A 1 297 ? 102.901 110.696 126.860 1.00 69.00  ? 288 PHE A CE1    1 
ATOM   2923 C CE2    . PHE A 1 297 ? 100.638 110.624 126.115 1.00 69.00  ? 288 PHE A CE2    1 
ATOM   2924 C CZ     . PHE A 1 297 ? 101.917 111.124 125.999 1.00 69.00  ? 288 PHE A CZ     1 
ATOM   2925 H H      . PHE A 1 297 ? 101.262 106.170 127.776 1.00 69.00  ? 288 PHE A H      1 
ATOM   2926 H HA     . PHE A 1 297 ? 102.948 107.591 129.148 1.00 69.00  ? 288 PHE A HA     1 
ATOM   2927 H HB2    . PHE A 1 297 ? 100.173 107.792 128.774 1.00 69.00  ? 288 PHE A HB2    1 
ATOM   2928 H HB3    . PHE A 1 297 ? 100.852 108.724 129.863 1.00 69.00  ? 288 PHE A HB3    1 
ATOM   2929 H HD1    . PHE A 1 297 ? 103.276 109.482 128.416 1.00 69.00  ? 288 PHE A HD1    1 
ATOM   2930 H HD2    . PHE A 1 297 ? 99.482  109.361 127.166 1.00 69.00  ? 288 PHE A HD2    1 
ATOM   2931 H HE1    . PHE A 1 297 ? 103.765 111.032 126.784 1.00 69.00  ? 288 PHE A HE1    1 
ATOM   2932 H HE2    . PHE A 1 297 ? 99.971  110.913 125.534 1.00 69.00  ? 288 PHE A HE2    1 
ATOM   2933 H HZ     . PHE A 1 297 ? 102.114 111.750 125.340 1.00 69.00  ? 288 PHE A HZ     1 
ATOM   2934 N N      . LYS A 1 298 ? 101.500 105.505 130.971 1.00 70.71  ? 289 LYS A N      1 
ATOM   2935 C CA     . LYS A 1 298 ? 101.397 105.043 132.350 1.00 70.71  ? 289 LYS A CA     1 
ATOM   2936 C C      . LYS A 1 298 ? 102.758 104.878 133.015 1.00 70.71  ? 289 LYS A C      1 
ATOM   2937 O O      . LYS A 1 298 ? 102.829 104.841 134.247 1.00 70.71  ? 289 LYS A O      1 
ATOM   2938 C CB     . LYS A 1 298 ? 100.627 103.722 132.407 1.00 70.71  ? 289 LYS A CB     1 
ATOM   2939 C CG     . LYS A 1 298 ? 99.176  103.823 131.951 1.00 70.71  ? 289 LYS A CG     1 
ATOM   2940 C CD     . LYS A 1 298 ? 98.363  104.760 132.837 1.00 70.71  ? 289 LYS A CD     1 
ATOM   2941 C CE     . LYS A 1 298 ? 96.912  104.848 132.383 1.00 70.71  ? 289 LYS A CE     1 
ATOM   2942 N NZ     . LYS A 1 298 ? 96.188  103.556 132.527 1.00 70.71  ? 289 LYS A NZ     1 
ATOM   2943 H H      . LYS A 1 298 ? 101.215 104.949 130.381 1.00 70.71  ? 289 LYS A H      1 
ATOM   2944 H HA     . LYS A 1 298 ? 100.905 105.702 132.863 1.00 70.71  ? 289 LYS A HA     1 
ATOM   2945 H HB2    . LYS A 1 298 ? 101.072 103.077 131.835 1.00 70.71  ? 289 LYS A HB2    1 
ATOM   2946 H HB3    . LYS A 1 298 ? 100.627 103.401 133.322 1.00 70.71  ? 289 LYS A HB3    1 
ATOM   2947 H HG2    . LYS A 1 298 ? 99.149  104.165 131.044 1.00 70.71  ? 289 LYS A HG2    1 
ATOM   2948 H HG3    . LYS A 1 298 ? 98.769  102.943 131.989 1.00 70.71  ? 289 LYS A HG3    1 
ATOM   2949 H HD2    . LYS A 1 298 ? 98.377  104.431 133.750 1.00 70.71  ? 289 LYS A HD2    1 
ATOM   2950 H HD3    . LYS A 1 298 ? 98.739  105.652 132.796 1.00 70.71  ? 289 LYS A HD3    1 
ATOM   2951 H HE2    . LYS A 1 298 ? 96.452  105.511 132.921 1.00 70.71  ? 289 LYS A HE2    1 
ATOM   2952 H HE3    . LYS A 1 298 ? 96.889  105.103 131.448 1.00 70.71  ? 289 LYS A HE3    1 
ATOM   2953 H HZ1    . LYS A 1 298 ? 95.346  103.648 132.255 1.00 70.71  ? 289 LYS A HZ1    1 
ATOM   2954 H HZ2    . LYS A 1 298 ? 96.584  102.928 132.035 1.00 70.71  ? 289 LYS A HZ2    1 
ATOM   2955 H HZ3    . LYS A 1 298 ? 96.191  103.299 133.379 1.00 70.71  ? 289 LYS A HZ3    1 
ATOM   2956 N N      . VAL A 1 299 ? 103.835 104.781 132.241 1.00 68.93  ? 290 VAL A N      1 
ATOM   2957 C CA     . VAL A 1 299 ? 105.178 104.688 132.805 1.00 68.93  ? 290 VAL A CA     1 
ATOM   2958 C C      . VAL A 1 299 ? 105.627 106.099 133.169 1.00 68.93  ? 290 VAL A C      1 
ATOM   2959 O O      . VAL A 1 299 ? 105.801 106.950 132.294 1.00 68.93  ? 290 VAL A O      1 
ATOM   2960 C CB     . VAL A 1 299 ? 106.157 104.027 131.830 1.00 68.93  ? 290 VAL A CB     1 
ATOM   2961 C CG1    . VAL A 1 299 ? 107.548 103.962 132.440 1.00 68.93  ? 290 VAL A CG1    1 
ATOM   2962 C CG2    . VAL A 1 299 ? 105.672 102.636 131.454 1.00 68.93  ? 290 VAL A CG2    1 
ATOM   2963 H H      . VAL A 1 299 ? 103.816 104.766 131.381 1.00 68.93  ? 290 VAL A H      1 
ATOM   2964 H HA     . VAL A 1 299 ? 105.150 104.157 133.617 1.00 68.93  ? 290 VAL A HA     1 
ATOM   2965 H HB     . VAL A 1 299 ? 106.207 104.559 131.021 1.00 68.93  ? 290 VAL A HB     1 
ATOM   2966 H HG11   . VAL A 1 299 ? 107.925 104.855 132.471 1.00 68.93  ? 290 VAL A HG11   1 
ATOM   2967 H HG12   . VAL A 1 299 ? 108.106 103.388 131.890 1.00 68.93  ? 290 VAL A HG12   1 
ATOM   2968 H HG13   . VAL A 1 299 ? 107.483 103.596 133.336 1.00 68.93  ? 290 VAL A HG13   1 
ATOM   2969 H HG21   . VAL A 1 299 ? 105.555 102.114 132.263 1.00 68.93  ? 290 VAL A HG21   1 
ATOM   2970 H HG22   . VAL A 1 299 ? 106.333 102.216 130.881 1.00 68.93  ? 290 VAL A HG22   1 
ATOM   2971 H HG23   . VAL A 1 299 ? 104.828 102.713 130.984 1.00 68.93  ? 290 VAL A HG23   1 
ATOM   2972 N N      . THR A 1 300 ? 105.825 106.346 134.465 1.00 69.81  ? 291 THR A N      1 
ATOM   2973 C CA     . THR A 1 300 ? 106.088 107.706 134.926 1.00 69.81  ? 291 THR A CA     1 
ATOM   2974 C C      . THR A 1 300 ? 107.387 108.253 134.349 1.00 69.81  ? 291 THR A C      1 
ATOM   2975 O O      . THR A 1 300 ? 107.459 109.430 133.977 1.00 69.81  ? 291 THR A O      1 
ATOM   2976 C CB     . THR A 1 300 ? 106.120 107.746 136.455 1.00 69.81  ? 291 THR A CB     1 
ATOM   2977 O OG1    . THR A 1 300 ? 106.265 109.101 136.896 1.00 69.81  ? 291 THR A OG1    1 
ATOM   2978 C CG2    . THR A 1 300 ? 107.272 106.911 137.000 1.00 69.81  ? 291 THR A CG2    1 
ATOM   2979 H H      . THR A 1 300 ? 105.812 105.752 135.087 1.00 69.81  ? 291 THR A H      1 
ATOM   2980 H HA     . THR A 1 300 ? 105.365 108.281 134.629 1.00 69.81  ? 291 THR A HA     1 
ATOM   2981 H HB     . THR A 1 300 ? 105.291 107.382 136.802 1.00 69.81  ? 291 THR A HB     1 
ATOM   2982 H HG1    . THR A 1 300 ? 106.996 109.416 136.630 1.00 69.81  ? 291 THR A HG1    1 
ATOM   2983 H HG21   . THR A 1 300 ? 108.115 107.366 136.848 1.00 69.81  ? 291 THR A HG21   1 
ATOM   2984 H HG22   . THR A 1 300 ? 107.158 106.777 137.954 1.00 69.81  ? 291 THR A HG22   1 
ATOM   2985 H HG23   . THR A 1 300 ? 107.295 106.046 136.564 1.00 69.81  ? 291 THR A HG23   1 
ATOM   2986 N N      . ALA A 1 301 ? 108.429 107.424 134.276 1.00 69.68  ? 292 ALA A N      1 
ATOM   2987 C CA     . ALA A 1 301 ? 109.710 107.905 133.770 1.00 69.68  ? 292 ALA A CA     1 
ATOM   2988 C C      . ALA A 1 301 ? 109.572 108.425 132.345 1.00 69.68  ? 292 ALA A C      1 
ATOM   2989 O O      . ALA A 1 301 ? 109.999 109.545 132.030 1.00 69.68  ? 292 ALA A O      1 
ATOM   2990 C CB     . ALA A 1 301 ? 110.750 106.787 133.839 1.00 69.68  ? 292 ALA A CB     1 
ATOM   2991 H H      . ALA A 1 301 ? 108.420 106.596 134.508 1.00 69.68  ? 292 ALA A H      1 
ATOM   2992 H HA     . ALA A 1 301 ? 110.017 108.636 134.328 1.00 69.68  ? 292 ALA A HA     1 
ATOM   2993 H HB1    . ALA A 1 301 ? 110.461 106.051 133.278 1.00 69.68  ? 292 ALA A HB1    1 
ATOM   2994 H HB2    . ALA A 1 301 ? 111.601 107.129 133.524 1.00 69.68  ? 292 ALA A HB2    1 
ATOM   2995 H HB3    . ALA A 1 301 ? 110.833 106.490 134.759 1.00 69.68  ? 292 ALA A HB3    1 
ATOM   2996 N N      . TYR A 1 302 ? 108.970 107.622 131.467 1.00 67.02  ? 293 TYR A N      1 
ATOM   2997 C CA     . TYR A 1 302 ? 108.764 108.063 130.094 1.00 67.02  ? 293 TYR A CA     1 
ATOM   2998 C C      . TYR A 1 302 ? 107.850 109.277 130.048 1.00 67.02  ? 293 TYR A C      1 
ATOM   2999 O O      . TYR A 1 302 ? 108.061 110.194 129.247 1.00 67.02  ? 293 TYR A O      1 
ATOM   3000 C CB     . TYR A 1 302 ? 108.185 106.926 129.255 1.00 67.02  ? 293 TYR A CB     1 
ATOM   3001 C CG     . TYR A 1 302 ? 107.941 107.315 127.816 1.00 67.02  ? 293 TYR A CG     1 
ATOM   3002 C CD1    . TYR A 1 302 ? 108.955 107.231 126.876 1.00 67.02  ? 293 TYR A CD1    1 
ATOM   3003 C CD2    . TYR A 1 302 ? 106.702 107.775 127.402 1.00 67.02  ? 293 TYR A CD2    1 
ATOM   3004 C CE1    . TYR A 1 302 ? 108.741 107.591 125.568 1.00 67.02  ? 293 TYR A CE1    1 
ATOM   3005 C CE2    . TYR A 1 302 ? 106.479 108.136 126.095 1.00 67.02  ? 293 TYR A CE2    1 
ATOM   3006 C CZ     . TYR A 1 302 ? 107.502 108.041 125.181 1.00 67.02  ? 293 TYR A CZ     1 
ATOM   3007 O OH     . TYR A 1 302 ? 107.286 108.400 123.874 1.00 67.02  ? 293 TYR A OH     1 
ATOM   3008 H H      . TYR A 1 302 ? 108.677 106.832 131.639 1.00 67.02  ? 293 TYR A H      1 
ATOM   3009 H HA     . TYR A 1 302 ? 109.619 108.315 129.710 1.00 67.02  ? 293 TYR A HA     1 
ATOM   3010 H HB2    . TYR A 1 302 ? 108.808 106.182 129.261 1.00 67.02  ? 293 TYR A HB2    1 
ATOM   3011 H HB3    . TYR A 1 302 ? 107.337 106.650 129.637 1.00 67.02  ? 293 TYR A HB3    1 
ATOM   3012 H HD1    . TYR A 1 302 ? 109.795 106.927 127.135 1.00 67.02  ? 293 TYR A HD1    1 
ATOM   3013 H HD2    . TYR A 1 302 ? 106.009 107.840 128.019 1.00 67.02  ? 293 TYR A HD2    1 
ATOM   3014 H HE1    . TYR A 1 302 ? 109.430 107.528 124.947 1.00 67.02  ? 293 TYR A HE1    1 
ATOM   3015 H HE2    . TYR A 1 302 ? 105.642 108.442 125.830 1.00 67.02  ? 293 TYR A HE2    1 
ATOM   3016 H HH     . TYR A 1 302 ? 107.997 108.321 123.434 1.00 67.02  ? 293 TYR A HH     1 
ATOM   3017 N N      . ALA A 1 303 ? 106.820 109.296 130.895 1.00 66.71  ? 294 ALA A N      1 
ATOM   3018 C CA     . ALA A 1 303 ? 105.902 110.428 130.904 1.00 66.71  ? 294 ALA A CA     1 
ATOM   3019 C C      . ALA A 1 303 ? 106.639 111.721 131.210 1.00 66.71  ? 294 ALA A C      1 
ATOM   3020 O O      . ALA A 1 303 ? 106.372 112.758 130.593 1.00 66.71  ? 294 ALA A O      1 
ATOM   3021 C CB     . ALA A 1 303 ? 104.789 110.193 131.923 1.00 66.71  ? 294 ALA A CB     1 
ATOM   3022 H H      . ALA A 1 303 ? 106.635 108.678 131.463 1.00 66.71  ? 294 ALA A H      1 
ATOM   3023 H HA     . ALA A 1 303 ? 105.496 110.513 130.028 1.00 66.71  ? 294 ALA A HA     1 
ATOM   3024 H HB1    . ALA A 1 303 ? 104.308 109.386 131.683 1.00 66.71  ? 294 ALA A HB1    1 
ATOM   3025 H HB2    . ALA A 1 303 ? 104.187 110.953 131.912 1.00 66.71  ? 294 ALA A HB2    1 
ATOM   3026 H HB3    . ALA A 1 303 ? 105.183 110.095 132.804 1.00 66.71  ? 294 ALA A HB3    1 
ATOM   3027 N N      . VAL A 1 304 ? 107.570 111.681 132.162 1.00 67.58  ? 295 VAL A N      1 
ATOM   3028 C CA     . VAL A 1 304 ? 108.316 112.883 132.517 1.00 67.58  ? 295 VAL A CA     1 
ATOM   3029 C C      . VAL A 1 304 ? 109.286 113.257 131.403 1.00 67.58  ? 295 VAL A C      1 
ATOM   3030 O O      . VAL A 1 304 ? 109.394 114.426 131.022 1.00 67.58  ? 295 VAL A O      1 
ATOM   3031 C CB     . VAL A 1 304 ? 109.048 112.689 133.857 1.00 67.58  ? 295 VAL A CB     1 
ATOM   3032 C CG1    . VAL A 1 304 ? 109.848 113.934 134.204 1.00 67.58  ? 295 VAL A CG1    1 
ATOM   3033 C CG2    . VAL A 1 304 ? 108.060 112.371 134.966 1.00 67.58  ? 295 VAL A CG2    1 
ATOM   3034 H H      . VAL A 1 304 ? 107.786 110.980 132.611 1.00 67.58  ? 295 VAL A H      1 
ATOM   3035 H HA     . VAL A 1 304 ? 107.692 113.617 132.625 1.00 67.58  ? 295 VAL A HA     1 
ATOM   3036 H HB     . VAL A 1 304 ? 109.665 111.945 133.779 1.00 67.58  ? 295 VAL A HB     1 
ATOM   3037 H HG11   . VAL A 1 304 ? 110.124 113.882 135.132 1.00 67.58  ? 295 VAL A HG11   1 
ATOM   3038 H HG12   . VAL A 1 304 ? 110.629 113.982 133.630 1.00 67.58  ? 295 VAL A HG12   1 
ATOM   3039 H HG13   . VAL A 1 304 ? 109.289 114.715 134.069 1.00 67.58  ? 295 VAL A HG13   1 
ATOM   3040 H HG21   . VAL A 1 304 ? 108.399 111.626 135.486 1.00 67.58  ? 295 VAL A HG21   1 
ATOM   3041 H HG22   . VAL A 1 304 ? 107.202 112.139 134.578 1.00 67.58  ? 295 VAL A HG22   1 
ATOM   3042 H HG23   . VAL A 1 304 ? 107.963 113.152 135.534 1.00 67.58  ? 295 VAL A HG23   1 
ATOM   3043 N N      . TRP A 1 305 ? 110.005 112.271 130.865 1.00 66.82  ? 296 TRP A N      1 
ATOM   3044 C CA     . TRP A 1 305 ? 111.031 112.571 129.869 1.00 66.82  ? 296 TRP A CA     1 
ATOM   3045 C C      . TRP A 1 305 ? 110.426 113.137 128.587 1.00 66.82  ? 296 TRP A C      1 
ATOM   3046 O O      . TRP A 1 305 ? 110.980 114.071 127.983 1.00 66.82  ? 296 TRP A O      1 
ATOM   3047 C CB     . TRP A 1 305 ? 111.835 111.308 129.572 1.00 66.82  ? 296 TRP A CB     1 
ATOM   3048 C CG     . TRP A 1 305 ? 112.865 111.482 128.516 1.00 66.82  ? 296 TRP A CG     1 
ATOM   3049 C CD1    . TRP A 1 305 ? 113.973 112.270 128.576 1.00 66.82  ? 296 TRP A CD1    1 
ATOM   3050 C CD2    . TRP A 1 305 ? 112.896 110.840 127.240 1.00 66.82  ? 296 TRP A CD2    1 
ATOM   3051 N NE1    . TRP A 1 305 ? 114.691 112.165 127.412 1.00 66.82  ? 296 TRP A NE1    1 
ATOM   3052 C CE2    . TRP A 1 305 ? 114.049 111.291 126.574 1.00 66.82  ? 296 TRP A CE2    1 
ATOM   3053 C CE3    . TRP A 1 305 ? 112.058 109.928 126.594 1.00 66.82  ? 296 TRP A CE3    1 
ATOM   3054 C CZ2    . TRP A 1 305 ? 114.386 110.863 125.295 1.00 66.82  ? 296 TRP A CZ2    1 
ATOM   3055 C CZ3    . TRP A 1 305 ? 112.393 109.505 125.323 1.00 66.82  ? 296 TRP A CZ3    1 
ATOM   3056 C CH2    . TRP A 1 305 ? 113.546 109.972 124.687 1.00 66.82  ? 296 TRP A CH2    1 
ATOM   3057 H H      . TRP A 1 305 ? 109.922 111.436 131.057 1.00 66.82  ? 296 TRP A H      1 
ATOM   3058 H HA     . TRP A 1 305 ? 111.638 113.235 130.231 1.00 66.82  ? 296 TRP A HA     1 
ATOM   3059 H HB2    . TRP A 1 305 ? 112.285 111.026 130.383 1.00 66.82  ? 296 TRP A HB2    1 
ATOM   3060 H HB3    . TRP A 1 305 ? 111.225 110.613 129.277 1.00 66.82  ? 296 TRP A HB3    1 
ATOM   3061 H HD1    . TRP A 1 305 ? 114.208 112.805 129.300 1.00 66.82  ? 296 TRP A HD1    1 
ATOM   3062 H HE1    . TRP A 1 305 ? 115.424 112.580 127.237 1.00 66.82  ? 296 TRP A HE1    1 
ATOM   3063 H HE3    . TRP A 1 305 ? 111.288 109.614 127.010 1.00 66.82  ? 296 TRP A HE3    1 
ATOM   3064 H HZ2    . TRP A 1 305 ? 115.153 111.172 124.869 1.00 66.82  ? 296 TRP A HZ2    1 
ATOM   3065 H HZ3    . TRP A 1 305 ? 111.842 108.898 124.884 1.00 66.82  ? 296 TRP A HZ3    1 
ATOM   3066 H HH2    . TRP A 1 305 ? 113.747 109.668 123.831 1.00 66.82  ? 296 TRP A HH2    1 
ATOM   3067 N N      . ALA A 1 306 ? 109.302 112.567 128.142 1.00 65.17  ? 297 ALA A N      1 
ATOM   3068 C CA     . ALA A 1 306 ? 108.702 112.980 126.879 1.00 65.17  ? 297 ALA A CA     1 
ATOM   3069 C C      . ALA A 1 306 ? 108.165 114.400 126.949 1.00 65.17  ? 297 ALA A C      1 
ATOM   3070 O O      . ALA A 1 306 ? 108.014 115.054 125.913 1.00 65.17  ? 297 ALA A O      1 
ATOM   3071 C CB     . ALA A 1 306 ? 107.585 112.014 126.489 1.00 65.17  ? 297 ALA A CB     1 
ATOM   3072 H H      . ALA A 1 306 ? 108.874 111.943 128.551 1.00 65.17  ? 297 ALA A H      1 
ATOM   3073 H HA     . ALA A 1 306 ? 109.379 112.951 126.185 1.00 65.17  ? 297 ALA A HA     1 
ATOM   3074 H HB1    . ALA A 1 306 ? 107.957 111.123 126.394 1.00 65.17  ? 297 ALA A HB1    1 
ATOM   3075 H HB2    . ALA A 1 306 ? 106.908 112.018 127.184 1.00 65.17  ? 297 ALA A HB2    1 
ATOM   3076 H HB3    . ALA A 1 306 ? 107.197 112.302 125.648 1.00 65.17  ? 297 ALA A HB3    1 
ATOM   3077 N N      . VAL A 1 307 ? 107.844 114.883 128.147 1.00 63.79  ? 298 VAL A N      1 
ATOM   3078 C CA     . VAL A 1 307 ? 107.463 116.280 128.287 1.00 63.79  ? 298 VAL A CA     1 
ATOM   3079 C C      . VAL A 1 307 ? 108.692 117.144 128.515 1.00 63.79  ? 298 VAL A C      1 
ATOM   3080 O O      . VAL A 1 307 ? 108.715 118.314 128.118 1.00 63.79  ? 298 VAL A O      1 
ATOM   3081 C CB     . VAL A 1 307 ? 106.444 116.449 129.425 1.00 63.79  ? 298 VAL A CB     1 
ATOM   3082 C CG1    . VAL A 1 307 ? 106.169 117.922 129.674 1.00 63.79  ? 298 VAL A CG1    1 
ATOM   3083 C CG2    . VAL A 1 307 ? 105.159 115.714 129.093 1.00 63.79  ? 298 VAL A CG2    1 
ATOM   3084 H H      . VAL A 1 307 ? 107.839 114.431 128.879 1.00 63.79  ? 298 VAL A H      1 
ATOM   3085 H HA     . VAL A 1 307 ? 107.039 116.578 127.467 1.00 63.79  ? 298 VAL A HA     1 
ATOM   3086 H HB     . VAL A 1 307 ? 106.810 116.068 130.238 1.00 63.79  ? 298 VAL A HB     1 
ATOM   3087 H HG11   . VAL A 1 307 ? 106.908 118.305 130.173 1.00 63.79  ? 298 VAL A HG11   1 
ATOM   3088 H HG12   . VAL A 1 307 ? 105.349 118.006 130.185 1.00 63.79  ? 298 VAL A HG12   1 
ATOM   3089 H HG13   . VAL A 1 307 ? 106.073 118.373 128.821 1.00 63.79  ? 298 VAL A HG13   1 
ATOM   3090 H HG21   . VAL A 1 307 ? 104.524 115.846 129.814 1.00 63.79  ? 298 VAL A HG21   1 
ATOM   3091 H HG22   . VAL A 1 307 ? 104.798 116.069 128.265 1.00 63.79  ? 298 VAL A HG22   1 
ATOM   3092 H HG23   . VAL A 1 307 ? 105.352 114.769 128.991 1.00 63.79  ? 298 VAL A HG23   1 
ATOM   3093 N N      . GLY A 1 308 ? 109.727 116.595 129.151 1.00 64.09  ? 299 GLY A N      1 
ATOM   3094 C CA     . GLY A 1 308 ? 110.919 117.384 129.411 1.00 64.09  ? 299 GLY A CA     1 
ATOM   3095 C C      . GLY A 1 308 ? 111.630 117.801 128.140 1.00 64.09  ? 299 GLY A C      1 
ATOM   3096 O O      . GLY A 1 308 ? 112.018 118.961 127.982 1.00 64.09  ? 299 GLY A O      1 
ATOM   3097 H H      . GLY A 1 308 ? 109.761 115.785 129.436 1.00 64.09  ? 299 GLY A H      1 
ATOM   3098 H HA2    . GLY A 1 308 ? 110.676 118.184 129.904 1.00 64.09  ? 299 GLY A HA2    1 
ATOM   3099 H HA3    . GLY A 1 308 ? 111.535 116.867 129.953 1.00 64.09  ? 299 GLY A HA3    1 
ATOM   3100 N N      . ILE A 1 309 ? 111.813 116.859 127.213 1.00 64.01  ? 300 ILE A N      1 
ATOM   3101 C CA     . ILE A 1 309 ? 112.583 117.163 126.003 1.00 64.01  ? 300 ILE A CA     1 
ATOM   3102 C C      . ILE A 1 309 ? 111.918 118.244 125.158 1.00 64.01  ? 300 ILE A C      1 
ATOM   3103 O O      . ILE A 1 309 ? 112.586 119.240 124.828 1.00 64.01  ? 300 ILE A O      1 
ATOM   3104 C CB     . ILE A 1 309 ? 112.855 115.873 125.211 1.00 64.01  ? 300 ILE A CB     1 
ATOM   3105 C CG1    . ILE A 1 309 ? 114.169 115.247 125.687 1.00 64.01  ? 300 ILE A CG1    1 
ATOM   3106 C CG2    . ILE A 1 309 ? 112.886 116.154 123.707 1.00 64.01  ? 300 ILE A CG2    1 
ATOM   3107 C CD1    . ILE A 1 309 ? 114.621 114.055 124.879 1.00 64.01  ? 300 ILE A CD1    1 
ATOM   3108 H H      . ILE A 1 309 ? 111.510 116.056 127.257 1.00 64.01  ? 300 ILE A H      1 
ATOM   3109 H HA     . ILE A 1 309 ? 113.444 117.514 126.279 1.00 64.01  ? 300 ILE A HA     1 
ATOM   3110 H HB     . ILE A 1 309 ? 112.138 115.244 125.389 1.00 64.01  ? 300 ILE A HB     1 
ATOM   3111 H HG12   . ILE A 1 309 ? 114.870 115.916 125.636 1.00 64.01  ? 300 ILE A HG12   1 
ATOM   3112 H HG13   . ILE A 1 309 ? 114.060 114.956 126.606 1.00 64.01  ? 300 ILE A HG13   1 
ATOM   3113 H HG21   . ILE A 1 309 ? 113.172 115.359 123.233 1.00 64.01  ? 300 ILE A HG21   1 
ATOM   3114 H HG22   . ILE A 1 309 ? 111.996 116.392 123.405 1.00 64.01  ? 300 ILE A HG22   1 
ATOM   3115 H HG23   . ILE A 1 309 ? 113.506 116.879 123.530 1.00 64.01  ? 300 ILE A HG23   1 
ATOM   3116 H HD11   . ILE A 1 309 ? 113.856 113.481 124.714 1.00 64.01  ? 300 ILE A HD11   1 
ATOM   3117 H HD12   . ILE A 1 309 ? 115.300 113.573 125.375 1.00 64.01  ? 300 ILE A HD12   1 
ATOM   3118 H HD13   . ILE A 1 309 ? 114.988 114.364 124.036 1.00 64.01  ? 300 ILE A HD13   1 
ATOM   3119 N N      . PRO A 1 310 ? 110.648 118.121 124.762 1.00 62.58  ? 301 PRO A N      1 
ATOM   3120 C CA     . PRO A 1 310 ? 110.032 119.197 123.968 1.00 62.58  ? 301 PRO A CA     1 
ATOM   3121 C C      . PRO A 1 310 ? 110.037 120.534 124.678 1.00 62.58  ? 301 PRO A C      1 
ATOM   3122 O O      . PRO A 1 310 ? 110.229 121.573 124.036 1.00 62.58  ? 301 PRO A O      1 
ATOM   3123 C CB     . PRO A 1 310 ? 108.605 118.684 123.730 1.00 62.58  ? 301 PRO A CB     1 
ATOM   3124 C CG     . PRO A 1 310 ? 108.689 117.215 123.911 1.00 62.58  ? 301 PRO A CG     1 
ATOM   3125 C CD     . PRO A 1 310 ? 109.733 116.987 124.955 1.00 62.58  ? 301 PRO A CD     1 
ATOM   3126 H HA     . PRO A 1 310 ? 110.486 119.286 123.115 1.00 62.58  ? 301 PRO A HA     1 
ATOM   3127 H HB2    . PRO A 1 310 ? 108.004 119.076 124.382 1.00 62.58  ? 301 PRO A HB2    1 
ATOM   3128 H HB3    . PRO A 1 310 ? 108.325 118.903 122.828 1.00 62.58  ? 301 PRO A HB3    1 
ATOM   3129 H HG2    . PRO A 1 310 ? 107.830 116.876 124.209 1.00 62.58  ? 301 PRO A HG2    1 
ATOM   3130 H HG3    . PRO A 1 310 ? 108.948 116.798 123.074 1.00 62.58  ? 301 PRO A HG3    1 
ATOM   3131 H HD2    . PRO A 1 310 ? 109.341 117.022 125.841 1.00 62.58  ? 301 PRO A HD2    1 
ATOM   3132 H HD3    . PRO A 1 310 ? 110.188 116.146 124.798 1.00 62.58  ? 301 PRO A HD3    1 
ATOM   3133 N N      . LEU A 1 311 ? 109.829 120.540 125.995 1.00 63.42  ? 302 LEU A N      1 
ATOM   3134 C CA     . LEU A 1 311 ? 109.921 121.787 126.743 1.00 63.42  ? 302 LEU A CA     1 
ATOM   3135 C C      . LEU A 1 311 ? 111.339 122.333 126.728 1.00 63.42  ? 302 LEU A C      1 
ATOM   3136 O O      . LEU A 1 311 ? 111.540 123.545 126.853 1.00 63.42  ? 302 LEU A O      1 
ATOM   3137 C CB     . LEU A 1 311 ? 109.448 121.570 128.180 1.00 63.42  ? 302 LEU A CB     1 
ATOM   3138 C CG     . LEU A 1 311 ? 109.624 122.748 129.138 1.00 63.42  ? 302 LEU A CG     1 
ATOM   3139 C CD1    . LEU A 1 311 ? 108.965 124.004 128.595 1.00 63.42  ? 302 LEU A CD1    1 
ATOM   3140 C CD2    . LEU A 1 311 ? 109.058 122.394 130.503 1.00 63.42  ? 302 LEU A CD2    1 
ATOM   3141 H H      . LEU A 1 311 ? 109.637 119.848 126.468 1.00 63.42  ? 302 LEU A H      1 
ATOM   3142 H HA     . LEU A 1 311 ? 109.341 122.446 126.331 1.00 63.42  ? 302 LEU A HA     1 
ATOM   3143 H HB2    . LEU A 1 311 ? 108.503 121.354 128.159 1.00 63.42  ? 302 LEU A HB2    1 
ATOM   3144 H HB3    . LEU A 1 311 ? 109.941 120.821 128.551 1.00 63.42  ? 302 LEU A HB3    1 
ATOM   3145 H HG     . LEU A 1 311 ? 110.570 122.930 129.249 1.00 63.42  ? 302 LEU A HG     1 
ATOM   3146 H HD11   . LEU A 1 311 ? 109.426 124.282 127.788 1.00 63.42  ? 302 LEU A HD11   1 
ATOM   3147 H HD12   . LEU A 1 311 ? 109.020 124.702 129.265 1.00 63.42  ? 302 LEU A HD12   1 
ATOM   3148 H HD13   . LEU A 1 311 ? 108.036 123.810 128.396 1.00 63.42  ? 302 LEU A HD13   1 
ATOM   3149 H HD21   . LEU A 1 311 ? 109.163 123.155 131.096 1.00 63.42  ? 302 LEU A HD21   1 
ATOM   3150 H HD22   . LEU A 1 311 ? 108.118 122.176 130.408 1.00 63.42  ? 302 LEU A HD22   1 
ATOM   3151 H HD23   . LEU A 1 311 ? 109.541 121.631 130.857 1.00 63.42  ? 302 LEU A HD23   1 
ATOM   3152 N N      . ALA A 1 312 ? 112.333 121.456 126.587 1.00 62.45  ? 303 ALA A N      1 
ATOM   3153 C CA     . ALA A 1 312 ? 113.719 121.903 126.532 1.00 62.45  ? 303 ALA A CA     1 
ATOM   3154 C C      . ALA A 1 312 ? 114.057 122.526 125.185 1.00 62.45  ? 303 ALA A C      1 
ATOM   3155 O O      . ALA A 1 312 ? 114.771 123.532 125.128 1.00 62.45  ? 303 ALA A O      1 
ATOM   3156 C CB     . ALA A 1 312 ? 114.657 120.731 126.816 1.00 62.45  ? 303 ALA A CB     1 
ATOM   3157 H H      . ALA A 1 312 ? 112.231 120.605 126.522 1.00 62.45  ? 303 ALA A H      1 
ATOM   3158 H HA     . ALA A 1 312 ? 113.861 122.574 127.217 1.00 62.45  ? 303 ALA A HA     1 
ATOM   3159 H HB1    . ALA A 1 312 ? 114.401 120.312 127.651 1.00 62.45  ? 303 ALA A HB1    1 
ATOM   3160 H HB2    . ALA A 1 312 ? 114.585 120.091 126.091 1.00 62.45  ? 303 ALA A HB2    1 
ATOM   3161 H HB3    . ALA A 1 312 ? 115.567 121.062 126.872 1.00 62.45  ? 303 ALA A HB3    1 
ATOM   3162 N N      . LEU A 1 313 ? 113.556 121.946 124.094 1.00 62.25  ? 304 LEU A N      1 
ATOM   3163 C CA     . LEU A 1 313 ? 113.939 122.379 122.754 1.00 62.25  ? 304 LEU A CA     1 
ATOM   3164 C C      . LEU A 1 313 ? 113.119 123.557 122.236 1.00 62.25  ? 304 LEU A C      1 
ATOM   3165 O O      . LEU A 1 313 ? 113.067 123.763 121.018 1.00 62.25  ? 304 LEU A O      1 
ATOM   3166 C CB     . LEU A 1 313 ? 113.826 121.213 121.771 1.00 62.25  ? 304 LEU A CB     1 
ATOM   3167 C CG     . LEU A 1 313 ? 114.747 120.022 122.020 1.00 62.25  ? 304 LEU A CG     1 
ATOM   3168 C CD1    . LEU A 1 313 ? 114.583 119.009 120.907 1.00 62.25  ? 304 LEU A CD1    1 
ATOM   3169 C CD2    . LEU A 1 313 ? 116.194 120.463 122.132 1.00 62.25  ? 304 LEU A CD2    1 
ATOM   3170 H H      . LEU A 1 313 ? 112.992 121.297 124.105 1.00 62.25  ? 304 LEU A H      1 
ATOM   3171 H HA     . LEU A 1 313 ? 114.866 122.664 122.776 1.00 62.25  ? 304 LEU A HA     1 
ATOM   3172 H HB2    . LEU A 1 313 ? 112.914 120.882 121.797 1.00 62.25  ? 304 LEU A HB2    1 
ATOM   3173 H HB3    . LEU A 1 313 ? 114.022 121.544 120.881 1.00 62.25  ? 304 LEU A HB3    1 
ATOM   3174 H HG     . LEU A 1 313 ? 114.496 119.596 122.854 1.00 62.25  ? 304 LEU A HG     1 
ATOM   3175 H HD11   . LEU A 1 313 ? 113.647 118.965 120.661 1.00 62.25  ? 304 LEU A HD11   1 
ATOM   3176 H HD12   . LEU A 1 313 ? 114.888 118.143 121.219 1.00 62.25  ? 304 LEU A HD12   1 
ATOM   3177 H HD13   . LEU A 1 313 ? 115.110 119.293 120.143 1.00 62.25  ? 304 LEU A HD13   1 
ATOM   3178 H HD21   . LEU A 1 313 ? 116.764 119.678 122.131 1.00 62.25  ? 304 LEU A HD21   1 
ATOM   3179 H HD22   . LEU A 1 313 ? 116.410 121.029 121.375 1.00 62.25  ? 304 LEU A HD22   1 
ATOM   3180 H HD23   . LEU A 1 313 ? 116.314 120.956 122.959 1.00 62.25  ? 304 LEU A HD23   1 
ATOM   3181 N N      . PHE A 1 314 ? 112.495 124.342 123.103 1.00 60.28  ? 305 PHE A N      1 
ATOM   3182 C CA     . PHE A 1 314 ? 111.633 125.422 122.622 1.00 60.28  ? 305 PHE A CA     1 
ATOM   3183 C C      . PHE A 1 314 ? 112.405 126.596 122.059 1.00 60.28  ? 305 PHE A C      1 
ATOM   3184 O O      . PHE A 1 314 ? 111.780 127.596 121.695 1.00 60.28  ? 305 PHE A O      1 
ATOM   3185 C CB     . PHE A 1 314 ? 110.719 125.901 123.748 1.00 60.28  ? 305 PHE A CB     1 
ATOM   3186 C CG     . PHE A 1 314 ? 109.301 126.116 123.318 1.00 60.28  ? 305 PHE A CG     1 
ATOM   3187 C CD1    . PHE A 1 314 ? 108.403 125.066 123.309 1.00 60.28  ? 305 PHE A CD1    1 
ATOM   3188 C CD2    . PHE A 1 314 ? 108.868 127.364 122.917 1.00 60.28  ? 305 PHE A CD2    1 
ATOM   3189 C CE1    . PHE A 1 314 ? 107.100 125.257 122.912 1.00 60.28  ? 305 PHE A CE1    1 
ATOM   3190 C CE2    . PHE A 1 314 ? 107.565 127.560 122.519 1.00 60.28  ? 305 PHE A CE2    1 
ATOM   3191 C CZ     . PHE A 1 314 ? 106.680 126.505 122.517 1.00 60.28  ? 305 PHE A CZ     1 
ATOM   3192 H H      . PHE A 1 314 ? 112.550 124.276 123.959 1.00 60.28  ? 305 PHE A H      1 
ATOM   3193 H HA     . PHE A 1 314 ? 111.068 125.078 121.914 1.00 60.28  ? 305 PHE A HA     1 
ATOM   3194 H HB2    . PHE A 1 314 ? 110.716 125.236 124.454 1.00 60.28  ? 305 PHE A HB2    1 
ATOM   3195 H HB3    . PHE A 1 314 ? 111.056 126.743 124.089 1.00 60.28  ? 305 PHE A HB3    1 
ATOM   3196 H HD1    . PHE A 1 314 ? 108.682 124.220 123.575 1.00 60.28  ? 305 PHE A HD1    1 
ATOM   3197 H HD2    . PHE A 1 314 ? 109.461 128.080 122.917 1.00 60.28  ? 305 PHE A HD2    1 
ATOM   3198 H HE1    . PHE A 1 314 ? 106.504 124.543 122.911 1.00 60.28  ? 305 PHE A HE1    1 
ATOM   3199 H HE2    . PHE A 1 314 ? 107.281 128.405 122.253 1.00 60.28  ? 305 PHE A HE2    1 
ATOM   3200 H HZ     . PHE A 1 314 ? 105.800 126.637 122.249 1.00 60.28  ? 305 PHE A HZ     1 
ATOM   3201 N N      . GLY A 1 315 ? 113.729 126.527 121.989 1.00 59.58  ? 306 GLY A N      1 
ATOM   3202 C CA     . GLY A 1 315 ? 114.514 127.573 121.365 1.00 59.58  ? 306 GLY A CA     1 
ATOM   3203 C C      . GLY A 1 315 ? 115.705 127.005 120.625 1.00 59.58  ? 306 GLY A C      1 
ATOM   3204 O O      . GLY A 1 315 ? 116.621 127.735 120.239 1.00 59.58  ? 306 GLY A O      1 
ATOM   3205 H H      . GLY A 1 315 ? 114.198 125.880 122.304 1.00 59.58  ? 306 GLY A H      1 
ATOM   3206 H HA2    . GLY A 1 315 ? 113.963 128.064 120.736 1.00 59.58  ? 306 GLY A HA2    1 
ATOM   3207 H HA3    . GLY A 1 315 ? 114.834 128.188 122.043 1.00 59.58  ? 306 GLY A HA3    1 
ATOM   3208 N N      . TYR A 1 316 ? 115.695 125.687 120.422 1.00 61.70  ? 307 TYR A N      1 
ATOM   3209 C CA     . TYR A 1 316 ? 116.853 125.014 119.848 1.00 61.70  ? 307 TYR A CA     1 
ATOM   3210 C C      . TYR A 1 316 ? 117.136 125.492 118.431 1.00 61.70  ? 307 TYR A C      1 
ATOM   3211 O O      . TYR A 1 316 ? 118.295 125.711 118.064 1.00 61.70  ? 307 TYR A O      1 
ATOM   3212 C CB     . TYR A 1 316 ? 116.626 123.505 119.869 1.00 61.70  ? 307 TYR A CB     1 
ATOM   3213 C CG     . TYR A 1 316 ? 117.614 122.715 119.048 1.00 61.70  ? 307 TYR A CG     1 
ATOM   3214 C CD1    . TYR A 1 316 ? 118.865 122.392 119.553 1.00 61.70  ? 307 TYR A CD1    1 
ATOM   3215 C CD2    . TYR A 1 316 ? 117.290 122.278 117.774 1.00 61.70  ? 307 TYR A CD2    1 
ATOM   3216 C CE1    . TYR A 1 316 ? 119.766 121.663 118.809 1.00 61.70  ? 307 TYR A CE1    1 
ATOM   3217 C CE2    . TYR A 1 316 ? 118.183 121.549 117.023 1.00 61.70  ? 307 TYR A CE2    1 
ATOM   3218 C CZ     . TYR A 1 316 ? 119.420 121.245 117.543 1.00 61.70  ? 307 TYR A CZ     1 
ATOM   3219 O OH     . TYR A 1 316 ? 120.313 120.517 116.793 1.00 61.70  ? 307 TYR A OH     1 
ATOM   3220 H H      . TYR A 1 316 ? 115.036 125.165 120.603 1.00 61.70  ? 307 TYR A H      1 
ATOM   3221 H HA     . TYR A 1 316 ? 117.633 125.208 120.391 1.00 61.70  ? 307 TYR A HA     1 
ATOM   3222 H HB2    . TYR A 1 316 ? 116.690 123.196 120.786 1.00 61.70  ? 307 TYR A HB2    1 
ATOM   3223 H HB3    . TYR A 1 316 ? 115.740 123.319 119.522 1.00 61.70  ? 307 TYR A HB3    1 
ATOM   3224 H HD1    . TYR A 1 316 ? 119.099 122.674 120.407 1.00 61.70  ? 307 TYR A HD1    1 
ATOM   3225 H HD2    . TYR A 1 316 ? 116.455 122.482 117.420 1.00 61.70  ? 307 TYR A HD2    1 
ATOM   3226 H HE1    . TYR A 1 316 ? 120.602 121.456 119.158 1.00 61.70  ? 307 TYR A HE1    1 
ATOM   3227 H HE2    . TYR A 1 316 ? 117.953 121.265 116.168 1.00 61.70  ? 307 TYR A HE2    1 
ATOM   3228 H HH     . TYR A 1 316 ? 120.962 120.282 117.269 1.00 61.70  ? 307 TYR A HH     1 
ATOM   3229 N N      . PHE A 1 317 ? 116.096 125.657 117.620 1.00 60.44  ? 308 PHE A N      1 
ATOM   3230 C CA     . PHE A 1 317 ? 116.260 125.947 116.203 1.00 60.44  ? 308 PHE A CA     1 
ATOM   3231 C C      . PHE A 1 317 ? 116.352 127.437 115.906 1.00 60.44  ? 308 PHE A C      1 
ATOM   3232 O O      . PHE A 1 317 ? 116.523 127.809 114.742 1.00 60.44  ? 308 PHE A O      1 
ATOM   3233 C CB     . PHE A 1 317 ? 115.101 125.333 115.412 1.00 60.44  ? 308 PHE A CB     1 
ATOM   3234 C CG     . PHE A 1 317 ? 115.345 125.252 113.931 1.00 60.44  ? 308 PHE A CG     1 
ATOM   3235 C CD1    . PHE A 1 317 ? 116.438 124.567 113.430 1.00 60.44  ? 308 PHE A CD1    1 
ATOM   3236 C CD2    . PHE A 1 317 ? 114.467 125.842 113.038 1.00 60.44  ? 308 PHE A CD2    1 
ATOM   3237 C CE1    . PHE A 1 317 ? 116.659 124.488 112.069 1.00 60.44  ? 308 PHE A CE1    1 
ATOM   3238 C CE2    . PHE A 1 317 ? 114.682 125.762 111.677 1.00 60.44  ? 308 PHE A CE2    1 
ATOM   3239 C CZ     . PHE A 1 317 ? 115.778 125.085 111.193 1.00 60.44  ? 308 PHE A CZ     1 
ATOM   3240 H H      . PHE A 1 317 ? 115.275 125.603 117.871 1.00 60.44  ? 308 PHE A H      1 
ATOM   3241 H HA     . PHE A 1 317 ? 117.083 125.534 115.898 1.00 60.44  ? 308 PHE A HA     1 
ATOM   3242 H HB2    . PHE A 1 317 ? 114.945 124.433 115.738 1.00 60.44  ? 308 PHE A HB2    1 
ATOM   3243 H HB3    . PHE A 1 317 ? 114.308 125.874 115.552 1.00 60.44  ? 308 PHE A HB3    1 
ATOM   3244 H HD1    . PHE A 1 317 ? 117.036 124.163 114.017 1.00 60.44  ? 308 PHE A HD1    1 
ATOM   3245 H HD2    . PHE A 1 317 ? 113.725 126.302 113.360 1.00 60.44  ? 308 PHE A HD2    1 
ATOM   3246 H HE1    . PHE A 1 317 ? 117.399 124.028 111.744 1.00 60.44  ? 308 PHE A HE1    1 
ATOM   3247 H HE2    . PHE A 1 317 ? 114.088 126.167 111.087 1.00 60.44  ? 308 PHE A HE2    1 
ATOM   3248 H HZ     . PHE A 1 317 ? 115.925 125.031 110.276 1.00 60.44  ? 308 PHE A HZ     1 
ATOM   3249 N N      . VAL A 1 318 ? 116.247 128.296 116.919 1.00 61.68  ? 309 VAL A N      1 
ATOM   3250 C CA     . VAL A 1 318 ? 116.364 129.735 116.682 1.00 61.68  ? 309 VAL A CA     1 
ATOM   3251 C C      . VAL A 1 318 ? 117.711 130.097 116.069 1.00 61.68  ? 309 VAL A C      1 
ATOM   3252 O O      . VAL A 1 318 ? 117.730 130.794 115.040 1.00 61.68  ? 309 VAL A O      1 
ATOM   3253 C CB     . VAL A 1 318 ? 116.092 130.505 117.987 1.00 61.68  ? 309 VAL A CB     1 
ATOM   3254 C CG1    . VAL A 1 318 ? 116.295 131.996 117.780 1.00 61.68  ? 309 VAL A CG1    1 
ATOM   3255 C CG2    . VAL A 1 318 ? 114.688 130.217 118.485 1.00 61.68  ? 309 VAL A CG2    1 
ATOM   3256 H H      . VAL A 1 318 ? 116.110 128.078 117.739 1.00 61.68  ? 309 VAL A H      1 
ATOM   3257 H HA     . VAL A 1 318 ? 115.681 129.995 116.045 1.00 61.68  ? 309 VAL A HA     1 
ATOM   3258 H HB     . VAL A 1 318 ? 116.718 130.208 118.666 1.00 61.68  ? 309 VAL A HB     1 
ATOM   3259 H HG11   . VAL A 1 318 ? 115.957 132.472 118.554 1.00 61.68  ? 309 VAL A HG11   1 
ATOM   3260 H HG12   . VAL A 1 318 ? 117.242 132.177 117.674 1.00 61.68  ? 309 VAL A HG12   1 
ATOM   3261 H HG13   . VAL A 1 318 ? 115.812 132.272 116.986 1.00 61.68  ? 309 VAL A HG13   1 
ATOM   3262 H HG21   . VAL A 1 318 ? 114.115 130.036 117.724 1.00 61.68  ? 309 VAL A HG21   1 
ATOM   3263 H HG22   . VAL A 1 318 ? 114.715 129.444 119.071 1.00 61.68  ? 309 VAL A HG22   1 
ATOM   3264 H HG23   . VAL A 1 318 ? 114.357 130.989 118.970 1.00 61.68  ? 309 VAL A HG23   1 
ATOM   3265 N N      . PRO A 1 319 ? 118.853 129.683 116.628 1.00 61.96  ? 310 PRO A N      1 
ATOM   3266 C CA     . PRO A 1 319 ? 120.132 130.101 116.032 1.00 61.96  ? 310 PRO A CA     1 
ATOM   3267 C C      . PRO A 1 319 ? 120.309 129.639 114.598 1.00 61.96  ? 310 PRO A C      1 
ATOM   3268 O O      . PRO A 1 319 ? 120.744 130.432 113.760 1.00 61.96  ? 310 PRO A O      1 
ATOM   3269 C CB     . PRO A 1 319 ? 121.176 129.479 116.970 1.00 61.96  ? 310 PRO A CB     1 
ATOM   3270 C CG     . PRO A 1 319 ? 120.465 128.386 117.670 1.00 61.96  ? 310 PRO A CG     1 
ATOM   3271 C CD     . PRO A 1 319 ? 119.055 128.845 117.820 1.00 61.96  ? 310 PRO A CD     1 
ATOM   3272 H HA     . PRO A 1 319 ? 120.214 131.067 116.065 1.00 61.96  ? 310 PRO A HA     1 
ATOM   3273 H HB2    . PRO A 1 319 ? 121.915 129.128 116.449 1.00 61.96  ? 310 PRO A HB2    1 
ATOM   3274 H HB3    . PRO A 1 319 ? 121.485 130.146 117.602 1.00 61.96  ? 310 PRO A HB3    1 
ATOM   3275 H HG2    . PRO A 1 319 ? 120.504 127.578 117.134 1.00 61.96  ? 310 PRO A HG2    1 
ATOM   3276 H HG3    . PRO A 1 319 ? 120.870 128.239 118.539 1.00 61.96  ? 310 PRO A HG3    1 
ATOM   3277 H HD2    . PRO A 1 319 ? 118.460 128.083 117.816 1.00 61.96  ? 310 PRO A HD2    1 
ATOM   3278 H HD3    . PRO A 1 319 ? 118.955 129.374 118.627 1.00 61.96  ? 310 PRO A HD3    1 
ATOM   3279 N N      . TYR A 1 320 ? 119.928 128.403 114.274 1.00 61.93  ? 311 TYR A N      1 
ATOM   3280 C CA     . TYR A 1 320 ? 120.146 127.903 112.923 1.00 61.93  ? 311 TYR A CA     1 
ATOM   3281 C C      . TYR A 1 320 ? 119.494 128.786 111.872 1.00 61.93  ? 311 TYR A C      1 
ATOM   3282 O O      . TYR A 1 320 ? 119.935 128.785 110.718 1.00 61.93  ? 311 TYR A O      1 
ATOM   3283 C CB     . TYR A 1 320 ? 119.615 126.477 112.795 1.00 61.93  ? 311 TYR A CB     1 
ATOM   3284 C CG     . TYR A 1 320 ? 120.537 125.426 113.367 1.00 61.93  ? 311 TYR A CG     1 
ATOM   3285 C CD1    . TYR A 1 320 ? 121.520 124.840 112.584 1.00 61.93  ? 311 TYR A CD1    1 
ATOM   3286 C CD2    . TYR A 1 320 ? 120.423 125.019 114.689 1.00 61.93  ? 311 TYR A CD2    1 
ATOM   3287 C CE1    . TYR A 1 320 ? 122.363 123.879 113.100 1.00 61.93  ? 311 TYR A CE1    1 
ATOM   3288 C CE2    . TYR A 1 320 ? 121.262 124.060 115.214 1.00 61.93  ? 311 TYR A CE2    1 
ATOM   3289 C CZ     . TYR A 1 320 ? 122.231 123.493 114.415 1.00 61.93  ? 311 TYR A CZ     1 
ATOM   3290 O OH     . TYR A 1 320 ? 123.070 122.535 114.933 1.00 61.93  ? 311 TYR A OH     1 
ATOM   3291 H H      . TYR A 1 320 ? 119.548 127.847 114.808 1.00 61.93  ? 311 TYR A H      1 
ATOM   3292 H HA     . TYR A 1 320 ? 121.100 127.885 112.746 1.00 61.93  ? 311 TYR A HA     1 
ATOM   3293 H HB2    . TYR A 1 320 ? 118.768 126.414 113.263 1.00 61.93  ? 311 TYR A HB2    1 
ATOM   3294 H HB3    . TYR A 1 320 ? 119.486 126.276 111.855 1.00 61.93  ? 311 TYR A HB3    1 
ATOM   3295 H HD1    . TYR A 1 320 ? 121.612 125.099 111.695 1.00 61.93  ? 311 TYR A HD1    1 
ATOM   3296 H HD2    . TYR A 1 320 ? 119.770 125.400 115.230 1.00 61.93  ? 311 TYR A HD2    1 
ATOM   3297 H HE1    . TYR A 1 320 ? 123.019 123.495 112.563 1.00 61.93  ? 311 TYR A HE1    1 
ATOM   3298 H HE2    . TYR A 1 320 ? 121.175 123.796 116.101 1.00 61.93  ? 311 TYR A HE2    1 
ATOM   3299 H HH     . TYR A 1 320 ? 122.884 122.397 115.741 1.00 61.93  ? 311 TYR A HH     1 
ATOM   3300 N N      . VAL A 1 321 ? 118.459 129.533 112.237 1.00 60.06  ? 312 VAL A N      1 
ATOM   3301 C CA     . VAL A 1 321 ? 117.762 130.413 111.309 1.00 60.06  ? 312 VAL A CA     1 
ATOM   3302 C C      . VAL A 1 321 ? 118.256 131.848 111.418 1.00 60.06  ? 312 VAL A C      1 
ATOM   3303 O O      . VAL A 1 321 ? 118.440 132.524 110.406 1.00 60.06  ? 312 VAL A O      1 
ATOM   3304 C CB     . VAL A 1 321 ? 116.237 130.330 111.544 1.00 60.06  ? 312 VAL A CB     1 
ATOM   3305 C CG1    . VAL A 1 321 ? 115.508 131.335 110.663 1.00 60.06  ? 312 VAL A CG1    1 
ATOM   3306 C CG2    . VAL A 1 321 ? 115.742 128.917 111.282 1.00 60.06  ? 312 VAL A CG2    1 
ATOM   3307 H H      . VAL A 1 321 ? 118.135 129.546 113.033 1.00 60.06  ? 312 VAL A H      1 
ATOM   3308 H HA     . VAL A 1 321 ? 117.937 130.113 110.404 1.00 60.06  ? 312 VAL A HA     1 
ATOM   3309 H HB     . VAL A 1 321 ? 116.045 130.547 112.470 1.00 60.06  ? 312 VAL A HB     1 
ATOM   3310 H HG11   . VAL A 1 321 ? 114.647 130.974 110.403 1.00 60.06  ? 312 VAL A HG11   1 
ATOM   3311 H HG12   . VAL A 1 321 ? 116.044 131.510 109.874 1.00 60.06  ? 312 VAL A HG12   1 
ATOM   3312 H HG13   . VAL A 1 321 ? 115.379 132.155 111.166 1.00 60.06  ? 312 VAL A HG13   1 
ATOM   3313 H HG21   . VAL A 1 321 ? 115.849 128.391 112.090 1.00 60.06  ? 312 VAL A HG21   1 
ATOM   3314 H HG22   . VAL A 1 321 ? 116.267 128.530 110.565 1.00 60.06  ? 312 VAL A HG22   1 
ATOM   3315 H HG23   . VAL A 1 321 ? 114.807 128.942 111.027 1.00 60.06  ? 312 VAL A HG23   1 
ATOM   3316 N N      . HIS A 1 322 ? 118.474 132.341 112.636 1.00 62.54  ? 313 HIS A N      1 
ATOM   3317 C CA     . HIS A 1 322 ? 118.734 133.763 112.829 1.00 62.54  ? 313 HIS A CA     1 
ATOM   3318 C C      . HIS A 1 322 ? 120.209 134.127 112.965 1.00 62.54  ? 313 HIS A C      1 
ATOM   3319 O O      . HIS A 1 322 ? 120.521 135.318 113.032 1.00 62.54  ? 313 HIS A O      1 
ATOM   3320 C CB     . HIS A 1 322 ? 117.980 134.268 114.063 1.00 62.54  ? 313 HIS A CB     1 
ATOM   3321 C CG     . HIS A 1 322 ? 116.512 134.431 113.839 1.00 62.54  ? 313 HIS A CG     1 
ATOM   3322 N ND1    . HIS A 1 322 ? 115.998 135.275 112.880 1.00 62.54  ? 313 HIS A ND1    1 
ATOM   3323 C CD2    . HIS A 1 322 ? 115.448 133.858 114.446 1.00 62.54  ? 313 HIS A CD2    1 
ATOM   3324 C CE1    . HIS A 1 322 ? 114.679 135.217 112.906 1.00 62.54  ? 313 HIS A CE1    1 
ATOM   3325 N NE2    . HIS A 1 322 ? 114.320 134.364 113.848 1.00 62.54  ? 313 HIS A NE2    1 
ATOM   3326 H H      . HIS A 1 322 ? 118.475 131.877 113.360 1.00 62.54  ? 313 HIS A H      1 
ATOM   3327 H HA     . HIS A 1 322 ? 118.387 134.246 112.064 1.00 62.54  ? 313 HIS A HA     1 
ATOM   3328 H HB2    . HIS A 1 322 ? 118.102 133.634 114.786 1.00 62.54  ? 313 HIS A HB2    1 
ATOM   3329 H HB3    . HIS A 1 322 ? 118.340 135.132 114.317 1.00 62.54  ? 313 HIS A HB3    1 
ATOM   3330 H HD1    . HIS A 1 322 ? 116.464 135.765 112.347 1.00 62.54  ? 313 HIS A HD1    1 
ATOM   3331 H HD2    . HIS A 1 322 ? 115.474 133.239 115.139 1.00 62.54  ? 313 HIS A HD2    1 
ATOM   3332 H HE1    . HIS A 1 322 ? 114.102 135.695 112.356 1.00 62.54  ? 313 HIS A HE1    1 
ATOM   3333 H HE2    . HIS A 1 322 ? 113.510 134.159 114.053 1.00 62.54  ? 313 HIS A HE2    1 
ATOM   3334 N N      . LEU A 1 323 ? 121.124 133.157 112.997 1.00 63.93  ? 314 LEU A N      1 
ATOM   3335 C CA     . LEU A 1 323 ? 122.524 133.489 113.232 1.00 63.93  ? 314 LEU A CA     1 
ATOM   3336 C C      . LEU A 1 323 ? 123.130 134.214 112.039 1.00 63.93  ? 314 LEU A C      1 
ATOM   3337 O O      . LEU A 1 323 ? 123.892 135.174 112.209 1.00 63.93  ? 314 LEU A O      1 
ATOM   3338 C CB     . LEU A 1 323 ? 123.310 132.218 113.547 1.00 63.93  ? 314 LEU A CB     1 
ATOM   3339 C CG     . LEU A 1 323 ? 124.823 132.369 113.707 1.00 63.93  ? 314 LEU A CG     1 
ATOM   3340 C CD1    . LEU A 1 323 ? 125.156 133.421 114.749 1.00 63.93  ? 314 LEU A CD1    1 
ATOM   3341 C CD2    . LEU A 1 323 ? 125.443 131.032 114.075 1.00 63.93  ? 314 LEU A CD2    1 
ATOM   3342 H H      . LEU A 1 323 ? 120.963 132.319 112.889 1.00 63.93  ? 314 LEU A H      1 
ATOM   3343 H HA     . LEU A 1 323 ? 122.582 134.078 114.002 1.00 63.93  ? 314 LEU A HA     1 
ATOM   3344 H HB2    . LEU A 1 323 ? 122.970 131.850 114.378 1.00 63.93  ? 314 LEU A HB2    1 
ATOM   3345 H HB3    . LEU A 1 323 ? 123.159 131.583 112.829 1.00 63.93  ? 314 LEU A HB3    1 
ATOM   3346 H HG     . LEU A 1 323 ? 125.205 132.652 112.861 1.00 63.93  ? 314 LEU A HG     1 
ATOM   3347 H HD11   . LEU A 1 323 ? 124.881 134.291 114.421 1.00 63.93  ? 314 LEU A HD11   1 
ATOM   3348 H HD12   . LEU A 1 323 ? 126.113 133.416 114.907 1.00 63.93  ? 314 LEU A HD12   1 
ATOM   3349 H HD13   . LEU A 1 323 ? 124.684 133.212 115.571 1.00 63.93  ? 314 LEU A HD13   1 
ATOM   3350 H HD21   . LEU A 1 323 ? 126.402 131.146 114.174 1.00 63.93  ? 314 LEU A HD21   1 
ATOM   3351 H HD22   . LEU A 1 323 ? 125.058 130.726 114.911 1.00 63.93  ? 314 LEU A HD22   1 
ATOM   3352 H HD23   . LEU A 1 323 ? 125.257 130.393 113.370 1.00 63.93  ? 314 LEU A HD23   1 
ATOM   3353 N N      . MET A 1 324 ? 122.813 133.766 110.824 1.00 63.88  ? 315 MET A N      1 
ATOM   3354 C CA     . MET A 1 324 ? 123.378 134.396 109.641 1.00 63.88  ? 315 MET A CA     1 
ATOM   3355 C C      . MET A 1 324 ? 122.863 135.813 109.448 1.00 63.88  ? 315 MET A C      1 
ATOM   3356 O O      . MET A 1 324 ? 123.538 136.619 108.802 1.00 63.88  ? 315 MET A O      1 
ATOM   3357 C CB     . MET A 1 324 ? 123.069 133.558 108.403 1.00 63.88  ? 315 MET A CB     1 
ATOM   3358 C CG     . MET A 1 324 ? 123.743 134.053 107.135 1.00 63.88  ? 315 MET A CG     1 
ATOM   3359 S SD     . MET A 1 324 ? 125.531 134.203 107.291 1.00 63.88  ? 315 MET A SD     1 
ATOM   3360 C CE     . MET A 1 324 ? 125.960 132.563 107.860 1.00 63.88  ? 315 MET A CE     1 
ATOM   3361 H H      . MET A 1 324 ? 122.281 133.110 110.663 1.00 63.88  ? 315 MET A H      1 
ATOM   3362 H HA     . MET A 1 324 ? 124.342 134.429 109.746 1.00 63.88  ? 315 MET A HA     1 
ATOM   3363 H HB2    . MET A 1 324 ? 123.357 132.645 108.561 1.00 63.88  ? 315 MET A HB2    1 
ATOM   3364 H HB3    . MET A 1 324 ? 122.111 133.575 108.251 1.00 63.88  ? 315 MET A HB3    1 
ATOM   3365 H HG2    . MET A 1 324 ? 123.559 133.425 106.419 1.00 63.88  ? 315 MET A HG2    1 
ATOM   3366 H HG3    . MET A 1 324 ? 123.388 134.926 106.908 1.00 63.88  ? 315 MET A HG3    1 
ATOM   3367 H HE1    . MET A 1 324 ? 125.621 132.441 108.761 1.00 63.88  ? 315 MET A HE1    1 
ATOM   3368 H HE2    . MET A 1 324 ? 126.925 132.472 107.855 1.00 63.88  ? 315 MET A HE2    1 
ATOM   3369 H HE3    . MET A 1 324 ? 125.564 131.907 107.265 1.00 63.88  ? 315 MET A HE3    1 
ATOM   3370 N N      . LYS A 1 325 ? 121.689 136.134 109.990 1.00 63.07  ? 316 LYS A N      1 
ATOM   3371 C CA     . LYS A 1 325 ? 121.182 137.498 109.934 1.00 63.07  ? 316 LYS A CA     1 
ATOM   3372 C C      . LYS A 1 325 ? 121.672 138.339 111.102 1.00 63.07  ? 316 LYS A C      1 
ATOM   3373 O O      . LYS A 1 325 ? 121.814 139.559 110.961 1.00 63.07  ? 316 LYS A O      1 
ATOM   3374 C CB     . LYS A 1 325 ? 119.653 137.492 109.905 1.00 63.07  ? 316 LYS A CB     1 
ATOM   3375 C CG     . LYS A 1 325 ? 119.022 138.873 109.820 1.00 63.07  ? 316 LYS A CG     1 
ATOM   3376 C CD     . LYS A 1 325 ? 119.485 139.632 108.590 1.00 63.07  ? 316 LYS A CD     1 
ATOM   3377 C CE     . LYS A 1 325 ? 118.779 140.971 108.469 1.00 63.07  ? 316 LYS A CE     1 
ATOM   3378 N NZ     . LYS A 1 325 ? 119.263 141.750 107.297 1.00 63.07  ? 316 LYS A NZ     1 
ATOM   3379 H H      . LYS A 1 325 ? 121.171 135.581 110.396 1.00 63.07  ? 316 LYS A H      1 
ATOM   3380 H HA     . LYS A 1 325 ? 121.498 137.911 109.115 1.00 63.07  ? 316 LYS A HA     1 
ATOM   3381 H HB2    . LYS A 1 325 ? 119.360 136.985 109.131 1.00 63.07  ? 316 LYS A HB2    1 
ATOM   3382 H HB3    . LYS A 1 325 ? 119.329 137.071 110.716 1.00 63.07  ? 316 LYS A HB3    1 
ATOM   3383 H HG2    . LYS A 1 325 ? 118.058 138.778 109.770 1.00 63.07  ? 316 LYS A HG2    1 
ATOM   3384 H HG3    . LYS A 1 325 ? 119.265 139.389 110.604 1.00 63.07  ? 316 LYS A HG3    1 
ATOM   3385 H HD2    . LYS A 1 325 ? 120.437 139.802 108.654 1.00 63.07  ? 316 LYS A HD2    1 
ATOM   3386 H HD3    . LYS A 1 325 ? 119.287 139.110 107.796 1.00 63.07  ? 316 LYS A HD3    1 
ATOM   3387 H HE2    . LYS A 1 325 ? 117.826 140.821 108.360 1.00 63.07  ? 316 LYS A HE2    1 
ATOM   3388 H HE3    . LYS A 1 325 ? 118.946 141.493 109.269 1.00 63.07  ? 316 LYS A HE3    1 
ATOM   3389 H HZ1    . LYS A 1 325 ? 118.822 142.521 107.241 1.00 63.07  ? 316 LYS A HZ1    1 
ATOM   3390 H HZ2    . LYS A 1 325 ? 120.132 141.920 107.384 1.00 63.07  ? 316 LYS A HZ2    1 
ATOM   3391 H HZ3    . LYS A 1 325 ? 119.132 141.287 106.549 1.00 63.07  ? 316 LYS A HZ3    1 
ATOM   3392 N N      . HIS A 1 326 ? 121.929 137.716 112.255 1.00 64.09  ? 317 HIS A N      1 
ATOM   3393 C CA     . HIS A 1 326 ? 122.605 138.424 113.335 1.00 64.09  ? 317 HIS A CA     1 
ATOM   3394 C C      . HIS A 1 326 ? 123.991 138.861 112.892 1.00 64.09  ? 317 HIS A C      1 
ATOM   3395 O O      . HIS A 1 326 ? 124.404 140.000 113.140 1.00 64.09  ? 317 HIS A O      1 
ATOM   3396 C CB     . HIS A 1 326 ? 122.692 137.535 114.573 1.00 64.09  ? 317 HIS A CB     1 
ATOM   3397 C CG     . HIS A 1 326 ? 123.468 138.143 115.697 1.00 64.09  ? 317 HIS A CG     1 
ATOM   3398 N ND1    . HIS A 1 326 ? 123.348 139.468 116.053 1.00 64.09  ? 317 HIS A ND1    1 
ATOM   3399 C CD2    . HIS A 1 326 ? 124.374 137.606 116.547 1.00 64.09  ? 317 HIS A CD2    1 
ATOM   3400 C CE1    . HIS A 1 326 ? 124.147 139.722 117.073 1.00 64.09  ? 317 HIS A CE1    1 
ATOM   3401 N NE2    . HIS A 1 326 ? 124.782 138.609 117.392 1.00 64.09  ? 317 HIS A NE2    1 
ATOM   3402 H H      . HIS A 1 326 ? 121.727 136.899 112.431 1.00 64.09  ? 317 HIS A H      1 
ATOM   3403 H HA     . HIS A 1 326 ? 122.096 139.217 113.565 1.00 64.09  ? 317 HIS A HA     1 
ATOM   3404 H HB2    . HIS A 1 326 ? 121.793 137.361 114.895 1.00 64.09  ? 317 HIS A HB2    1 
ATOM   3405 H HB3    . HIS A 1 326 ? 123.121 136.700 114.331 1.00 64.09  ? 317 HIS A HB3    1 
ATOM   3406 H HD1    . HIS A 1 326 ? 122.833 140.041 115.670 1.00 64.09  ? 317 HIS A HD1    1 
ATOM   3407 H HD2    . HIS A 1 326 ? 124.668 136.723 116.557 1.00 64.09  ? 317 HIS A HD2    1 
ATOM   3408 H HE1    . HIS A 1 326 ? 124.246 140.544 117.495 1.00 64.09  ? 317 HIS A HE1    1 
ATOM   3409 N N      . VAL A 1 327 ? 124.720 137.969 112.220 1.00 66.54  ? 318 VAL A N      1 
ATOM   3410 C CA     . VAL A 1 327 ? 125.908 138.397 111.504 1.00 66.54  ? 318 VAL A CA     1 
ATOM   3411 C C      . VAL A 1 327 ? 125.486 139.476 110.511 1.00 66.54  ? 318 VAL A C      1 
ATOM   3412 O O      . VAL A 1 327 ? 124.309 139.611 110.162 1.00 66.54  ? 318 VAL A O      1 
ATOM   3413 C CB     . VAL A 1 327 ? 126.596 137.217 110.801 1.00 66.54  ? 318 VAL A CB     1 
ATOM   3414 C CG1    . VAL A 1 327 ? 127.830 137.680 110.054 1.00 66.54  ? 318 VAL A CG1    1 
ATOM   3415 C CG2    . VAL A 1 327 ? 126.972 136.149 111.811 1.00 66.54  ? 318 VAL A CG2    1 
ATOM   3416 H H      . VAL A 1 327 ? 124.546 137.128 112.164 1.00 66.54  ? 318 VAL A H      1 
ATOM   3417 H HA     . VAL A 1 327 ? 126.540 138.788 112.130 1.00 66.54  ? 318 VAL A HA     1 
ATOM   3418 H HB     . VAL A 1 327 ? 125.982 136.825 110.159 1.00 66.54  ? 318 VAL A HB     1 
ATOM   3419 H HG11   . VAL A 1 327 ? 128.384 136.910 109.849 1.00 66.54  ? 318 VAL A HG11   1 
ATOM   3420 H HG12   . VAL A 1 327 ? 127.557 138.117 109.233 1.00 66.54  ? 318 VAL A HG12   1 
ATOM   3421 H HG13   . VAL A 1 327 ? 128.322 138.301 110.614 1.00 66.54  ? 318 VAL A HG13   1 
ATOM   3422 H HG21   . VAL A 1 327 ? 127.423 135.423 111.352 1.00 66.54  ? 318 VAL A HG21   1 
ATOM   3423 H HG22   . VAL A 1 327 ? 127.562 136.537 112.476 1.00 66.54  ? 318 VAL A HG22   1 
ATOM   3424 H HG23   . VAL A 1 327 ? 126.169 135.819 112.239 1.00 66.54  ? 318 VAL A HG23   1 
ATOM   3425 N N      . ASN A 1 328 ? 126.464 140.247 110.048 1.00 68.67  ? 319 ASN A N      1 
ATOM   3426 C CA     . ASN A 1 328 ? 126.314 141.544 109.392 1.00 68.67  ? 319 ASN A CA     1 
ATOM   3427 C C      . ASN A 1 328 ? 126.159 142.636 110.443 1.00 68.67  ? 319 ASN A C      1 
ATOM   3428 O O      . ASN A 1 328 ? 126.019 143.806 110.074 1.00 68.67  ? 319 ASN A O      1 
ATOM   3429 C CB     . ASN A 1 328 ? 125.124 141.612 108.418 1.00 68.67  ? 319 ASN A CB     1 
ATOM   3430 C CG     . ASN A 1 328 ? 125.174 140.533 107.353 1.00 68.67  ? 319 ASN A CG     1 
ATOM   3431 O OD1    . ASN A 1 328 ? 125.174 139.342 107.657 1.00 68.67  ? 319 ASN A OD1    1 
ATOM   3432 N ND2    . ASN A 1 328 ? 125.204 140.950 106.093 1.00 68.67  ? 319 ASN A ND2    1 
ATOM   3433 H H      . ASN A 1 328 ? 127.291 140.026 110.109 1.00 68.67  ? 319 ASN A H      1 
ATOM   3434 H HA     . ASN A 1 328 ? 127.119 141.732 108.886 1.00 68.67  ? 319 ASN A HA     1 
ATOM   3435 H HB2    . ASN A 1 328 ? 124.295 141.522 108.911 1.00 68.67  ? 319 ASN A HB2    1 
ATOM   3436 H HB3    . ASN A 1 328 ? 125.142 142.470 107.965 1.00 68.67  ? 319 ASN A HB3    1 
ATOM   3437 H HD21   . ASN A 1 328 ? 125.201 141.792 105.921 1.00 68.67  ? 319 ASN A HD21   1 
ATOM   3438 H HD22   . ASN A 1 328 ? 125.232 140.379 105.450 1.00 68.67  ? 319 ASN A HD22   1 
ATOM   3439 N N      . GLU A 1 329 ? 126.163 142.295 111.734 1.00 68.44  ? 320 GLU A N      1 
ATOM   3440 C CA     . GLU A 1 329 ? 126.483 143.291 112.751 1.00 68.44  ? 320 GLU A CA     1 
ATOM   3441 C C      . GLU A 1 329 ? 127.912 143.781 112.572 1.00 68.44  ? 320 GLU A C      1 
ATOM   3442 O O      . GLU A 1 329 ? 128.195 144.976 112.720 1.00 68.44  ? 320 GLU A O      1 
ATOM   3443 C CB     . GLU A 1 329 ? 126.288 142.702 114.149 1.00 68.44  ? 320 GLU A CB     1 
ATOM   3444 C CG     . GLU A 1 329 ? 126.749 143.609 115.285 1.00 68.44  ? 320 GLU A CG     1 
ATOM   3445 C CD     . GLU A 1 329 ? 126.531 142.990 116.651 1.00 68.44  ? 320 GLU A CD     1 
ATOM   3446 O OE1    . GLU A 1 329 ? 125.808 141.979 116.738 1.00 68.44  ? 320 GLU A OE1    1 
ATOM   3447 O OE2    . GLU A 1 329 ? 127.089 143.512 117.637 1.00 68.44  ? 320 GLU A OE2    1 
ATOM   3448 H H      . GLU A 1 329 ? 125.986 141.512 112.042 1.00 68.44  ? 320 GLU A H      1 
ATOM   3449 H HA     . GLU A 1 329 ? 125.886 144.050 112.654 1.00 68.44  ? 320 GLU A HA     1 
ATOM   3450 H HB2    . GLU A 1 329 ? 125.344 142.520 114.280 1.00 68.44  ? 320 GLU A HB2    1 
ATOM   3451 H HB3    . GLU A 1 329 ? 126.792 141.875 114.209 1.00 68.44  ? 320 GLU A HB3    1 
ATOM   3452 H HG2    . GLU A 1 329 ? 127.698 143.782 115.192 1.00 68.44  ? 320 GLU A HG2    1 
ATOM   3453 H HG3    . GLU A 1 329 ? 126.252 144.442 115.249 1.00 68.44  ? 320 GLU A HG3    1 
ATOM   3454 N N      . ARG A 1 330 ? 128.827 142.863 112.264 1.00 69.48  ? 321 ARG A N      1 
ATOM   3455 C CA     . ARG A 1 330 ? 130.180 143.208 111.830 1.00 69.48  ? 321 ARG A CA     1 
ATOM   3456 C C      . ARG A 1 330 ? 130.204 143.218 110.301 1.00 69.48  ? 321 ARG A C      1 
ATOM   3457 O O      . ARG A 1 330 ? 130.767 142.346 109.637 1.00 69.48  ? 321 ARG A O      1 
ATOM   3458 C CB     . ARG A 1 330 ? 131.190 142.225 112.405 1.00 69.48  ? 321 ARG A CB     1 
ATOM   3459 C CG     . ARG A 1 330 ? 130.960 141.885 113.864 1.00 69.48  ? 321 ARG A CG     1 
ATOM   3460 C CD     . ARG A 1 330 ? 131.887 140.784 114.317 1.00 69.48  ? 321 ARG A CD     1 
ATOM   3461 N NE     . ARG A 1 330 ? 131.383 140.117 115.509 1.00 69.48  ? 321 ARG A NE     1 
ATOM   3462 C CZ     . ARG A 1 330 ? 130.460 139.167 115.501 1.00 69.48  ? 321 ARG A CZ     1 
ATOM   3463 N NH1    . ARG A 1 330 ? 129.904 138.751 114.376 1.00 69.48  ? 321 ARG A NH1    1 
ATOM   3464 N NH2    . ARG A 1 330 ? 130.084 138.619 116.652 1.00 69.48  ? 321 ARG A NH2    1 
ATOM   3465 H H      . ARG A 1 330 ? 128.687 142.015 112.302 1.00 69.48  ? 321 ARG A H      1 
ATOM   3466 H HA     . ARG A 1 330 ? 130.406 144.097 112.146 1.00 69.48  ? 321 ARG A HA     1 
ATOM   3467 H HB2    . ARG A 1 330 ? 131.141 141.400 111.899 1.00 69.48  ? 321 ARG A HB2    1 
ATOM   3468 H HB3    . ARG A 1 330 ? 132.079 142.605 112.325 1.00 69.48  ? 321 ARG A HB3    1 
ATOM   3469 H HG2    . ARG A 1 330 ? 131.129 142.670 114.408 1.00 69.48  ? 321 ARG A HG2    1 
ATOM   3470 H HG3    . ARG A 1 330 ? 130.049 141.578 113.989 1.00 69.48  ? 321 ARG A HG3    1 
ATOM   3471 H HD2    . ARG A 1 330 ? 131.974 140.124 113.611 1.00 69.48  ? 321 ARG A HD2    1 
ATOM   3472 H HD3    . ARG A 1 330 ? 132.754 141.165 114.527 1.00 69.48  ? 321 ARG A HD3    1 
ATOM   3473 H HE     . ARG A 1 330 ? 131.706 140.357 116.270 1.00 69.48  ? 321 ARG A HE     1 
ATOM   3474 H HH11   . ARG A 1 330 ? 130.138 139.096 113.624 1.00 69.48  ? 321 ARG A HH11   1 
ATOM   3475 H HH12   . ARG A 1 330 ? 129.306 138.133 114.396 1.00 69.48  ? 321 ARG A HH12   1 
ATOM   3476 H HH21   . ARG A 1 330 ? 130.439 138.884 117.389 1.00 69.48  ? 321 ARG A HH21   1 
ATOM   3477 H HH22   . ARG A 1 330 ? 129.485 138.004 116.661 1.00 69.48  ? 321 ARG A HH22   1 
ATOM   3478 N N      . PHE A 1 331 ? 129.554 144.241 109.746 1.00 75.63  ? 322 PHE A N      1 
ATOM   3479 C CA     . PHE A 1 331 ? 129.334 144.287 108.305 1.00 75.63  ? 322 PHE A CA     1 
ATOM   3480 C C      . PHE A 1 331 ? 130.647 144.365 107.535 1.00 75.63  ? 322 PHE A C      1 
ATOM   3481 O O      . PHE A 1 331 ? 130.759 143.818 106.432 1.00 75.63  ? 322 PHE A O      1 
ATOM   3482 C CB     . PHE A 1 331 ? 128.437 145.474 107.952 1.00 75.63  ? 322 PHE A CB     1 
ATOM   3483 C CG     . PHE A 1 331 ? 128.965 146.797 108.430 1.00 75.63  ? 322 PHE A CG     1 
ATOM   3484 C CD1    . PHE A 1 331 ? 129.841 147.533 107.648 1.00 75.63  ? 322 PHE A CD1    1 
ATOM   3485 C CD2    . PHE A 1 331 ? 128.582 147.308 109.660 1.00 75.63  ? 322 PHE A CD2    1 
ATOM   3486 C CE1    . PHE A 1 331 ? 130.328 148.750 108.087 1.00 75.63  ? 322 PHE A CE1    1 
ATOM   3487 C CE2    . PHE A 1 331 ? 129.066 148.524 110.103 1.00 75.63  ? 322 PHE A CE2    1 
ATOM   3488 C CZ     . PHE A 1 331 ? 129.939 149.246 109.315 1.00 75.63  ? 322 PHE A CZ     1 
ATOM   3489 H H      . PHE A 1 331 ? 129.234 144.908 110.181 1.00 75.63  ? 322 PHE A H      1 
ATOM   3490 H HA     . PHE A 1 331 ? 128.875 143.477 108.031 1.00 75.63  ? 322 PHE A HA     1 
ATOM   3491 H HB2    . PHE A 1 331 ? 128.347 145.521 106.988 1.00 75.63  ? 322 PHE A HB2    1 
ATOM   3492 H HB3    . PHE A 1 331 ? 127.566 145.338 108.357 1.00 75.63  ? 322 PHE A HB3    1 
ATOM   3493 H HD1    . PHE A 1 331 ? 130.107 147.203 106.820 1.00 75.63  ? 322 PHE A HD1    1 
ATOM   3494 H HD2    . PHE A 1 331 ? 127.994 146.825 110.194 1.00 75.63  ? 322 PHE A HD2    1 
ATOM   3495 H HE1    . PHE A 1 331 ? 130.916 149.236 107.554 1.00 75.63  ? 322 PHE A HE1    1 
ATOM   3496 H HE2    . PHE A 1 331 ? 128.802 148.856 110.931 1.00 75.63  ? 322 PHE A HE2    1 
ATOM   3497 H HZ     . PHE A 1 331 ? 130.265 150.065 109.611 1.00 75.63  ? 322 PHE A HZ     1 
ATOM   3498 N N      . GLN A 1 332 ? 131.647 145.046 108.089 1.00 78.72  ? 323 GLN A N      1 
ATOM   3499 C CA     . GLN A 1 332 ? 132.881 145.302 107.357 1.00 78.72  ? 323 GLN A CA     1 
ATOM   3500 C C      . GLN A 1 332 ? 133.896 144.175 107.520 1.00 78.72  ? 323 GLN A C      1 
ATOM   3501 O O      . GLN A 1 332 ? 134.410 143.652 106.528 1.00 78.72  ? 323 GLN A O      1 
ATOM   3502 C CB     . GLN A 1 332 ? 133.490 146.630 107.818 1.00 78.72  ? 323 GLN A CB     1 
ATOM   3503 C CG     . GLN A 1 332 ? 134.672 147.104 106.983 1.00 78.72  ? 323 GLN A CG     1 
ATOM   3504 C CD     . GLN A 1 332 ? 134.280 147.454 105.561 1.00 78.72  ? 323 GLN A CD     1 
ATOM   3505 O OE1    . GLN A 1 332 ? 133.097 147.519 105.228 1.00 78.72  ? 323 GLN A OE1    1 
ATOM   3506 N NE2    . GLN A 1 332 ? 135.277 147.683 104.713 1.00 78.72  ? 323 GLN A NE2    1 
ATOM   3507 H H      . GLN A 1 332 ? 131.635 145.370 108.886 1.00 78.72  ? 323 GLN A H      1 
ATOM   3508 H HA     . GLN A 1 332 ? 132.674 145.381 106.412 1.00 78.72  ? 323 GLN A HA     1 
ATOM   3509 H HB2    . GLN A 1 332 ? 132.806 147.317 107.779 1.00 78.72  ? 323 GLN A HB2    1 
ATOM   3510 H HB3    . GLN A 1 332 ? 133.798 146.528 108.732 1.00 78.72  ? 323 GLN A HB3    1 
ATOM   3511 H HG2    . GLN A 1 332 ? 135.048 147.898 107.393 1.00 78.72  ? 323 GLN A HG2    1 
ATOM   3512 H HG3    . GLN A 1 332 ? 135.340 146.402 106.947 1.00 78.72  ? 323 GLN A HG3    1 
ATOM   3513 H HE21   . GLN A 1 332 ? 136.092 147.628 104.982 1.00 78.72  ? 323 GLN A HE21   1 
ATOM   3514 H HE22   . GLN A 1 332 ? 135.107 147.886 103.894 1.00 78.72  ? 323 GLN A HE22   1 
ATOM   3515 N N      . ASP A 1 333 ? 134.189 143.791 108.763 1.00 76.47  ? 324 ASP A N      1 
ATOM   3516 C CA     . ASP A 1 333 ? 135.235 142.811 109.029 1.00 76.47  ? 324 ASP A CA     1 
ATOM   3517 C C      . ASP A 1 333 ? 134.854 141.402 108.599 1.00 76.47  ? 324 ASP A C      1 
ATOM   3518 O O      . ASP A 1 333 ? 135.715 140.516 108.613 1.00 76.47  ? 324 ASP A O      1 
ATOM   3519 C CB     . ASP A 1 333 ? 135.581 142.810 110.519 1.00 76.47  ? 324 ASP A CB     1 
ATOM   3520 C CG     . ASP A 1 333 ? 135.926 144.192 111.037 1.00 76.47  ? 324 ASP A CG     1 
ATOM   3521 O OD1    . ASP A 1 333 ? 136.411 145.024 110.241 1.00 76.47  ? 324 ASP A OD1    1 
ATOM   3522 O OD2    . ASP A 1 333 ? 135.710 144.445 112.241 1.00 76.47  ? 324 ASP A OD2    1 
ATOM   3523 H H      . ASP A 1 333 ? 133.794 144.083 109.468 1.00 76.47  ? 324 ASP A H      1 
ATOM   3524 H HA     . ASP A 1 333 ? 136.034 143.064 108.539 1.00 76.47  ? 324 ASP A HA     1 
ATOM   3525 H HB2    . ASP A 1 333 ? 134.818 142.483 111.020 1.00 76.47  ? 324 ASP A HB2    1 
ATOM   3526 H HB3    . ASP A 1 333 ? 136.347 142.235 110.666 1.00 76.47  ? 324 ASP A HB3    1 
ATOM   3527 N N      . GLU A 1 334 ? 133.600 141.170 108.222 1.00 78.17  ? 325 GLU A N      1 
ATOM   3528 C CA     . GLU A 1 334 ? 133.157 139.830 107.864 1.00 78.17  ? 325 GLU A CA     1 
ATOM   3529 C C      . GLU A 1 334 ? 133.694 139.434 106.495 1.00 78.17  ? 325 GLU A C      1 
ATOM   3530 O O      . GLU A 1 334 ? 132.926 139.260 105.544 1.00 78.17  ? 325 GLU A O      1 
ATOM   3531 C CB     . GLU A 1 334 ? 131.627 139.747 107.887 1.00 78.17  ? 325 GLU A CB     1 
ATOM   3532 C CG     . GLU A 1 334 ? 130.918 140.778 107.016 1.00 78.17  ? 325 GLU A CG     1 
ATOM   3533 C CD     . GLU A 1 334 ? 129.414 140.774 107.206 1.00 78.17  ? 325 GLU A CD     1 
ATOM   3534 O OE1    . GLU A 1 334 ? 128.926 140.044 108.093 1.00 78.17  ? 325 GLU A OE1    1 
ATOM   3535 O OE2    . GLU A 1 334 ? 128.719 141.502 106.467 1.00 78.17  ? 325 GLU A OE2    1 
ATOM   3536 H H      . GLU A 1 334 ? 132.990 141.773 108.169 1.00 78.17  ? 325 GLU A H      1 
ATOM   3537 H HA     . GLU A 1 334 ? 133.502 139.198 108.514 1.00 78.17  ? 325 GLU A HA     1 
ATOM   3538 H HB2    . GLU A 1 334 ? 131.359 138.868 107.577 1.00 78.17  ? 325 GLU A HB2    1 
ATOM   3539 H HB3    . GLU A 1 334 ? 131.324 139.877 108.800 1.00 78.17  ? 325 GLU A HB3    1 
ATOM   3540 H HG2    . GLU A 1 334 ? 131.240 141.662 107.243 1.00 78.17  ? 325 GLU A HG2    1 
ATOM   3541 H HG3    . GLU A 1 334 ? 131.097 140.590 106.082 1.00 78.17  ? 325 GLU A HG3    1 
ATOM   3542 N N      . LYS A 1 335 ? 135.015 139.281 106.386 1.00 80.48  ? 326 LYS A N      1 
ATOM   3543 C CA     . LYS A 1 335 ? 135.597 138.848 105.121 1.00 80.48  ? 326 LYS A CA     1 
ATOM   3544 C C      . LYS A 1 335 ? 135.092 137.469 104.724 1.00 80.48  ? 326 LYS A C      1 
ATOM   3545 O O      . LYS A 1 335 ? 135.108 137.119 103.539 1.00 80.48  ? 326 LYS A O      1 
ATOM   3546 C CB     . LYS A 1 335 ? 137.122 138.852 105.218 1.00 80.48  ? 326 LYS A CB     1 
ATOM   3547 C CG     . LYS A 1 335 ? 137.823 138.569 103.899 1.00 80.48  ? 326 LYS A CG     1 
ATOM   3548 C CD     . LYS A 1 335 ? 139.328 138.748 104.007 1.00 80.48  ? 326 LYS A CD     1 
ATOM   3549 C CE     . LYS A 1 335 ? 139.713 140.212 104.155 1.00 80.48  ? 326 LYS A CE     1 
ATOM   3550 N NZ     . LYS A 1 335 ? 141.190 140.399 104.183 1.00 80.48  ? 326 LYS A NZ     1 
ATOM   3551 H H      . LYS A 1 335 ? 135.583 139.417 107.017 1.00 80.48  ? 326 LYS A H      1 
ATOM   3552 H HA     . LYS A 1 335 ? 135.340 139.474 104.426 1.00 80.48  ? 326 LYS A HA     1 
ATOM   3553 H HB2    . LYS A 1 335 ? 137.407 139.724 105.531 1.00 80.48  ? 326 LYS A HB2    1 
ATOM   3554 H HB3    . LYS A 1 335 ? 137.395 138.170 105.851 1.00 80.48  ? 326 LYS A HB3    1 
ATOM   3555 H HG2    . LYS A 1 335 ? 137.645 137.653 103.633 1.00 80.48  ? 326 LYS A HG2    1 
ATOM   3556 H HG3    . LYS A 1 335 ? 137.493 139.184 103.225 1.00 80.48  ? 326 LYS A HG3    1 
ATOM   3557 H HD2    . LYS A 1 335 ? 139.652 138.270 104.786 1.00 80.48  ? 326 LYS A HD2    1 
ATOM   3558 H HD3    . LYS A 1 335 ? 139.749 138.404 103.204 1.00 80.48  ? 326 LYS A HD3    1 
ATOM   3559 H HE2    . LYS A 1 335 ? 139.359 140.713 103.404 1.00 80.48  ? 326 LYS A HE2    1 
ATOM   3560 H HE3    . LYS A 1 335 ? 139.355 140.557 104.987 1.00 80.48  ? 326 LYS A HE3    1 
ATOM   3561 H HZ1    . LYS A 1 335 ? 141.384 141.261 104.293 1.00 80.48  ? 326 LYS A HZ1    1 
ATOM   3562 H HZ2    . LYS A 1 335 ? 141.546 140.118 103.417 1.00 80.48  ? 326 LYS A HZ2    1 
ATOM   3563 H HZ3    . LYS A 1 335 ? 141.543 139.935 104.855 1.00 80.48  ? 326 LYS A HZ3    1 
ATOM   3564 N N      . ASN A 1 336 ? 134.651 136.673 105.695 1.00 76.89  ? 327 ASN A N      1 
ATOM   3565 C CA     . ASN A 1 336 ? 134.044 135.377 105.431 1.00 76.89  ? 327 ASN A CA     1 
ATOM   3566 C C      . ASN A 1 336 ? 132.977 135.121 106.481 1.00 76.89  ? 327 ASN A C      1 
ATOM   3567 O O      . ASN A 1 336 ? 133.250 135.221 107.680 1.00 76.89  ? 327 ASN A O      1 
ATOM   3568 C CB     . ASN A 1 336 ? 135.089 134.259 105.455 1.00 76.89  ? 327 ASN A CB     1 
ATOM   3569 C CG     . ASN A 1 336 ? 134.491 132.898 105.176 1.00 76.89  ? 327 ASN A CG     1 
ATOM   3570 O OD1    . ASN A 1 336 ? 133.739 132.359 105.988 1.00 76.89  ? 327 ASN A OD1    1 
ATOM   3571 N ND2    . ASN A 1 336 ? 134.833 132.326 104.028 1.00 76.89  ? 327 ASN A ND2    1 
ATOM   3572 H H      . ASN A 1 336 ? 134.693 136.867 106.531 1.00 76.89  ? 327 ASN A H      1 
ATOM   3573 H HA     . ASN A 1 336 ? 133.622 135.386 104.557 1.00 76.89  ? 327 ASN A HA     1 
ATOM   3574 H HB2    . ASN A 1 336 ? 135.760 134.438 104.778 1.00 76.89  ? 327 ASN A HB2    1 
ATOM   3575 H HB3    . ASN A 1 336 ? 135.502 134.232 106.333 1.00 76.89  ? 327 ASN A HB3    1 
ATOM   3576 H HD21   . ASN A 1 336 ? 135.364 132.732 103.487 1.00 76.89  ? 327 ASN A HD21   1 
ATOM   3577 H HD22   . ASN A 1 336 ? 134.523 131.551 103.824 1.00 76.89  ? 327 ASN A HD22   1 
ATOM   3578 N N      . LYS A 1 337 ? 131.767 134.789 106.032 1.00 74.30  ? 328 LYS A N      1 
ATOM   3579 C CA     . LYS A 1 337 ? 130.644 134.529 106.926 1.00 74.30  ? 328 LYS A CA     1 
ATOM   3580 C C      . LYS A 1 337 ? 130.345 133.044 107.076 1.00 74.30  ? 328 LYS A C      1 
ATOM   3581 O O      . LYS A 1 337 ? 130.131 132.563 108.192 1.00 74.30  ? 328 LYS A O      1 
ATOM   3582 C CB     . LYS A 1 337 ? 129.386 135.242 106.420 1.00 74.30  ? 328 LYS A CB     1 
ATOM   3583 C CG     . LYS A 1 337 ? 129.475 136.753 106.397 1.00 74.30  ? 328 LYS A CG     1 
ATOM   3584 C CD     . LYS A 1 337 ? 128.088 137.384 106.436 1.00 74.30  ? 328 LYS A CD     1 
ATOM   3585 C CE     . LYS A 1 337 ? 127.221 136.963 105.256 1.00 74.30  ? 328 LYS A CE     1 
ATOM   3586 N NZ     . LYS A 1 337 ? 125.815 137.439 105.406 1.00 74.30  ? 328 LYS A NZ     1 
ATOM   3587 H H      . LYS A 1 337 ? 131.570 134.707 105.199 1.00 74.30  ? 328 LYS A H      1 
ATOM   3588 H HA     . LYS A 1 337 ? 130.852 134.882 107.806 1.00 74.30  ? 328 LYS A HA     1 
ATOM   3589 H HB2    . LYS A 1 337 ? 129.209 134.946 105.513 1.00 74.30  ? 328 LYS A HB2    1 
ATOM   3590 H HB3    . LYS A 1 337 ? 128.641 135.000 106.993 1.00 74.30  ? 328 LYS A HB3    1 
ATOM   3591 H HG2    . LYS A 1 337 ? 129.970 137.056 107.175 1.00 74.30  ? 328 LYS A HG2    1 
ATOM   3592 H HG3    . LYS A 1 337 ? 129.918 137.037 105.583 1.00 74.30  ? 328 LYS A HG3    1 
ATOM   3593 H HD2    . LYS A 1 337 ? 127.637 137.108 107.250 1.00 74.30  ? 328 LYS A HD2    1 
ATOM   3594 H HD3    . LYS A 1 337 ? 128.177 138.349 106.415 1.00 74.30  ? 328 LYS A HD3    1 
ATOM   3595 H HE2    . LYS A 1 337 ? 127.584 137.344 104.441 1.00 74.30  ? 328 LYS A HE2    1 
ATOM   3596 H HE3    . LYS A 1 337 ? 127.199 135.996 105.193 1.00 74.30  ? 328 LYS A HE3    1 
ATOM   3597 H HZ1    . LYS A 1 337 ? 125.445 137.073 106.128 1.00 74.30  ? 328 LYS A HZ1    1 
ATOM   3598 H HZ2    . LYS A 1 337 ? 125.339 137.210 104.690 1.00 74.30  ? 328 LYS A HZ2    1 
ATOM   3599 H HZ3    . LYS A 1 337 ? 125.802 138.325 105.492 1.00 74.30  ? 328 LYS A HZ3    1 
ATOM   3600 N N      . GLU A 1 338 ? 130.333 132.303 105.968 1.00 71.40  ? 329 GLU A N      1 
ATOM   3601 C CA     . GLU A 1 338 ? 129.842 130.931 105.995 1.00 71.40  ? 329 GLU A CA     1 
ATOM   3602 C C      . GLU A 1 338 ? 130.591 130.065 106.995 1.00 71.40  ? 329 GLU A C      1 
ATOM   3603 O O      . GLU A 1 338 ? 130.034 129.072 107.469 1.00 71.40  ? 329 GLU A O      1 
ATOM   3604 C CB     . GLU A 1 338 ? 129.935 130.306 104.599 1.00 71.40  ? 329 GLU A CB     1 
ATOM   3605 C CG     . GLU A 1 338 ? 131.353 130.132 104.054 1.00 71.40  ? 329 GLU A CG     1 
ATOM   3606 C CD     . GLU A 1 338 ? 131.947 131.421 103.520 1.00 71.40  ? 329 GLU A CD     1 
ATOM   3607 O OE1    . GLU A 1 338 ? 131.290 132.477 103.637 1.00 71.40  ? 329 GLU A OE1    1 
ATOM   3608 O OE2    . GLU A 1 338 ? 133.071 131.377 102.980 1.00 71.40  ? 329 GLU A OE2    1 
ATOM   3609 H H      . GLU A 1 338 ? 130.594 132.576 105.197 1.00 71.40  ? 329 GLU A H      1 
ATOM   3610 H HA     . GLU A 1 338 ? 128.908 130.940 106.254 1.00 71.40  ? 329 GLU A HA     1 
ATOM   3611 H HB2    . GLU A 1 338 ? 129.525 129.427 104.629 1.00 71.40  ? 329 GLU A HB2    1 
ATOM   3612 H HB3    . GLU A 1 338 ? 129.449 130.868 103.976 1.00 71.40  ? 329 GLU A HB3    1 
ATOM   3613 H HG2    . GLU A 1 338 ? 131.935 129.806 104.758 1.00 71.40  ? 329 GLU A HG2    1 
ATOM   3614 H HG3    . GLU A 1 338 ? 131.331 129.492 103.325 1.00 71.40  ? 329 GLU A HG3    1 
ATOM   3615 N N      . VAL A 1 339 ? 131.834 130.413 107.326 1.00 71.25  ? 330 VAL A N      1 
ATOM   3616 C CA     . VAL A 1 339 ? 132.600 129.599 108.265 1.00 71.25  ? 330 VAL A CA     1 
ATOM   3617 C C      . VAL A 1 339 ? 131.907 129.555 109.621 1.00 71.25  ? 330 VAL A C      1 
ATOM   3618 O O      . VAL A 1 339 ? 131.923 128.526 110.309 1.00 71.25  ? 330 VAL A O      1 
ATOM   3619 C CB     . VAL A 1 339 ? 134.042 130.128 108.381 1.00 71.25  ? 330 VAL A CB     1 
ATOM   3620 C CG1    . VAL A 1 339 ? 134.055 131.567 108.883 1.00 71.25  ? 330 VAL A CG1    1 
ATOM   3621 C CG2    . VAL A 1 339 ? 134.865 129.232 109.294 1.00 71.25  ? 330 VAL A CG2    1 
ATOM   3622 H H      . VAL A 1 339 ? 132.251 131.102 107.025 1.00 71.25  ? 330 VAL A H      1 
ATOM   3623 H HA     . VAL A 1 339 ? 132.645 128.691 107.926 1.00 71.25  ? 330 VAL A HA     1 
ATOM   3624 H HB     . VAL A 1 339 ? 134.452 130.116 107.502 1.00 71.25  ? 330 VAL A HB     1 
ATOM   3625 H HG11   . VAL A 1 339 ? 134.364 131.577 109.802 1.00 71.25  ? 330 VAL A HG11   1 
ATOM   3626 H HG12   . VAL A 1 339 ? 133.161 131.937 108.831 1.00 71.25  ? 330 VAL A HG12   1 
ATOM   3627 H HG13   . VAL A 1 339 ? 134.657 132.087 108.327 1.00 71.25  ? 330 VAL A HG13   1 
ATOM   3628 H HG21   . VAL A 1 339 ? 134.536 129.313 110.202 1.00 71.25  ? 330 VAL A HG21   1 
ATOM   3629 H HG22   . VAL A 1 339 ? 135.794 129.511 109.254 1.00 71.25  ? 330 VAL A HG22   1 
ATOM   3630 H HG23   . VAL A 1 339 ? 134.784 128.314 108.991 1.00 71.25  ? 330 VAL A HG23   1 
ATOM   3631 N N      . VAL A 1 340 ? 131.297 130.671 110.033 1.00 68.65  ? 331 VAL A N      1 
ATOM   3632 C CA     . VAL A 1 340 ? 130.681 130.736 111.356 1.00 68.65  ? 331 VAL A CA     1 
ATOM   3633 C C      . VAL A 1 340 ? 129.543 129.734 111.476 1.00 68.65  ? 331 VAL A C      1 
ATOM   3634 O O      . VAL A 1 340 ? 129.240 129.258 112.576 1.00 68.65  ? 331 VAL A O      1 
ATOM   3635 C CB     . VAL A 1 340 ? 130.198 132.169 111.654 1.00 68.65  ? 331 VAL A CB     1 
ATOM   3636 C CG1    . VAL A 1 340 ? 129.523 132.226 113.011 1.00 68.65  ? 331 VAL A CG1    1 
ATOM   3637 C CG2    . VAL A 1 340 ? 131.361 133.145 111.596 1.00 68.65  ? 331 VAL A CG2    1 
ATOM   3638 H H      . VAL A 1 340 ? 131.228 131.392 109.570 1.00 68.65  ? 331 VAL A H      1 
ATOM   3639 H HA     . VAL A 1 340 ? 131.348 130.505 112.021 1.00 68.65  ? 331 VAL A HA     1 
ATOM   3640 H HB     . VAL A 1 340 ? 129.550 132.431 110.982 1.00 68.65  ? 331 VAL A HB     1 
ATOM   3641 H HG11   . VAL A 1 340 ? 129.426 133.155 113.275 1.00 68.65  ? 331 VAL A HG11   1 
ATOM   3642 H HG12   . VAL A 1 340 ? 128.649 131.809 112.951 1.00 68.65  ? 331 VAL A HG12   1 
ATOM   3643 H HG13   . VAL A 1 340 ? 130.073 131.756 113.656 1.00 68.65  ? 331 VAL A HG13   1 
ATOM   3644 H HG21   . VAL A 1 340 ? 132.051 132.849 112.210 1.00 68.65  ? 331 VAL A HG21   1 
ATOM   3645 H HG22   . VAL A 1 340 ? 131.046 134.026 111.850 1.00 68.65  ? 331 VAL A HG22   1 
ATOM   3646 H HG23   . VAL A 1 340 ? 131.710 133.167 110.691 1.00 68.65  ? 331 VAL A HG23   1 
ATOM   3647 N N      . LEU A 1 341 ? 128.891 129.403 110.362 1.00 66.16  ? 332 LEU A N      1 
ATOM   3648 C CA     . LEU A 1 341 ? 127.849 128.384 110.367 1.00 66.16  ? 332 LEU A CA     1 
ATOM   3649 C C      . LEU A 1 341 ? 128.398 126.996 110.076 1.00 66.16  ? 332 LEU A C      1 
ATOM   3650 O O      . LEU A 1 341 ? 127.874 126.004 110.595 1.00 66.16  ? 332 LEU A O      1 
ATOM   3651 C CB     . LEU A 1 341 ? 126.770 128.739 109.342 1.00 66.16  ? 332 LEU A CB     1 
ATOM   3652 C CG     . LEU A 1 341 ? 125.492 127.903 109.384 1.00 66.16  ? 332 LEU A CG     1 
ATOM   3653 C CD1    . LEU A 1 341 ? 124.295 128.772 109.042 1.00 66.16  ? 332 LEU A CD1    1 
ATOM   3654 C CD2    . LEU A 1 341 ? 125.583 126.721 108.434 1.00 66.16  ? 332 LEU A CD2    1 
ATOM   3655 H H      . LEU A 1 341 ? 129.035 129.756 109.591 1.00 66.16  ? 332 LEU A H      1 
ATOM   3656 H HA     . LEU A 1 341 ? 127.431 128.363 111.242 1.00 66.16  ? 332 LEU A HA     1 
ATOM   3657 H HB2    . LEU A 1 341 ? 126.513 129.664 109.480 1.00 66.16  ? 332 LEU A HB2    1 
ATOM   3658 H HB3    . LEU A 1 341 ? 127.151 128.642 108.455 1.00 66.16  ? 332 LEU A HB3    1 
ATOM   3659 H HG     . LEU A 1 341 ? 125.369 127.559 110.283 1.00 66.16  ? 332 LEU A HG     1 
ATOM   3660 H HD11   . LEU A 1 341 ? 124.212 129.472 109.707 1.00 66.16  ? 332 LEU A HD11   1 
ATOM   3661 H HD12   . LEU A 1 341 ? 123.497 128.221 109.040 1.00 66.16  ? 332 LEU A HD12   1 
ATOM   3662 H HD13   . LEU A 1 341 ? 124.429 129.163 108.164 1.00 66.16  ? 332 LEU A HD13   1 
ATOM   3663 H HD21   . LEU A 1 341 ? 125.829 127.042 107.552 1.00 66.16  ? 332 LEU A HD21   1 
ATOM   3664 H HD22   . LEU A 1 341 ? 124.718 126.283 108.395 1.00 66.16  ? 332 LEU A HD22   1 
ATOM   3665 H HD23   . LEU A 1 341 ? 126.252 126.099 108.758 1.00 66.16  ? 332 LEU A HD23   1 
ATOM   3666 N N      . MET A 1 342 ? 129.450 126.911 109.263 1.00 69.40  ? 333 MET A N      1 
ATOM   3667 C CA     . MET A 1 342 ? 130.071 125.627 108.964 1.00 69.40  ? 333 MET A CA     1 
ATOM   3668 C C      . MET A 1 342 ? 130.650 124.992 110.221 1.00 69.40  ? 333 MET A C      1 
ATOM   3669 O O      . MET A 1 342 ? 130.578 123.768 110.404 1.00 69.40  ? 333 MET A O      1 
ATOM   3670 C CB     . MET A 1 342 ? 131.162 125.828 107.911 1.00 69.40  ? 333 MET A CB     1 
ATOM   3671 C CG     . MET A 1 342 ? 131.969 124.589 107.580 1.00 69.40  ? 333 MET A CG     1 
ATOM   3672 S SD     . MET A 1 342 ? 133.361 124.938 106.489 1.00 69.40  ? 333 MET A SD     1 
ATOM   3673 C CE     . MET A 1 342 ? 132.523 125.604 105.054 1.00 69.40  ? 333 MET A CE     1 
ATOM   3674 H H      . MET A 1 342 ? 129.820 127.582 108.873 1.00 69.40  ? 333 MET A H      1 
ATOM   3675 H HA     . MET A 1 342 ? 129.401 125.032 108.592 1.00 69.40  ? 333 MET A HA     1 
ATOM   3676 H HB2    . MET A 1 342 ? 130.742 126.133 107.092 1.00 69.40  ? 333 MET A HB2    1 
ATOM   3677 H HB3    . MET A 1 342 ? 131.780 126.503 108.232 1.00 69.40  ? 333 MET A HB3    1 
ATOM   3678 H HG2    . MET A 1 342 ? 132.325 124.205 108.395 1.00 69.40  ? 333 MET A HG2    1 
ATOM   3679 H HG3    . MET A 1 342 ? 131.391 123.950 107.138 1.00 69.40  ? 333 MET A HG3    1 
ATOM   3680 H HE1    . MET A 1 342 ? 131.850 124.971 104.760 1.00 69.40  ? 333 MET A HE1    1 
ATOM   3681 H HE2    . MET A 1 342 ? 133.173 125.747 104.348 1.00 69.40  ? 333 MET A HE2    1 
ATOM   3682 H HE3    . MET A 1 342 ? 132.105 126.445 105.295 1.00 69.40  ? 333 MET A HE3    1 
ATOM   3683 N N      . CYS A 1 343 ? 131.240 125.808 111.093 1.00 68.67  ? 334 CYS A N      1 
ATOM   3684 C CA     . CYS A 1 343 ? 131.911 125.276 112.267 1.00 68.67  ? 334 CYS A CA     1 
ATOM   3685 C C      . CYS A 1 343 ? 130.944 124.705 113.294 1.00 68.67  ? 334 CYS A C      1 
ATOM   3686 O O      . CYS A 1 343 ? 131.399 124.068 114.249 1.00 68.67  ? 334 CYS A O      1 
ATOM   3687 C CB     . CYS A 1 343 ? 132.778 126.359 112.904 1.00 68.67  ? 334 CYS A CB     1 
ATOM   3688 S SG     . CYS A 1 343 ? 134.279 126.717 111.964 1.00 68.67  ? 334 CYS A SG     1 
ATOM   3689 H H      . CYS A 1 343 ? 131.263 126.666 111.027 1.00 68.67  ? 334 CYS A H      1 
ATOM   3690 H HA     . CYS A 1 343 ? 132.498 124.561 111.983 1.00 68.67  ? 334 CYS A HA     1 
ATOM   3691 H HB2    . CYS A 1 343 ? 132.262 127.178 112.967 1.00 68.67  ? 334 CYS A HB2    1 
ATOM   3692 H HB3    . CYS A 1 343 ? 133.044 126.067 113.791 1.00 68.67  ? 334 CYS A HB3    1 
ATOM   3693 H HG     . CYS A 1 343 ? 133.969 127.083 110.864 1.00 68.67  ? 334 CYS A HG     1 
ATOM   3694 N N      . ILE A 1 344 ? 129.636 124.916 113.140 1.00 66.22  ? 335 ILE A N      1 
ATOM   3695 C CA     . ILE A 1 344 ? 128.684 124.184 113.968 1.00 66.22  ? 335 ILE A CA     1 
ATOM   3696 C C      . ILE A 1 344 ? 128.681 122.710 113.582 1.00 66.22  ? 335 ILE A C      1 
ATOM   3697 O O      . ILE A 1 344 ? 128.822 121.826 114.434 1.00 66.22  ? 335 ILE A O      1 
ATOM   3698 C CB     . ILE A 1 344 ? 127.276 124.795 113.850 1.00 66.22  ? 335 ILE A CB     1 
ATOM   3699 C CG1    . ILE A 1 344 ? 127.262 126.208 114.437 1.00 66.22  ? 335 ILE A CG1    1 
ATOM   3700 C CG2    . ILE A 1 344 ? 126.255 123.902 114.549 1.00 66.22  ? 335 ILE A CG2    1 
ATOM   3701 C CD1    . ILE A 1 344 ? 125.911 126.892 114.394 1.00 66.22  ? 335 ILE A CD1    1 
ATOM   3702 H H      . ILE A 1 344 ? 129.284 125.465 112.580 1.00 66.22  ? 335 ILE A H      1 
ATOM   3703 H HA     . ILE A 1 344 ? 128.959 124.248 114.896 1.00 66.22  ? 335 ILE A HA     1 
ATOM   3704 H HB     . ILE A 1 344 ? 127.043 124.851 112.911 1.00 66.22  ? 335 ILE A HB     1 
ATOM   3705 H HG12   . ILE A 1 344 ? 127.540 126.163 115.366 1.00 66.22  ? 335 ILE A HG12   1 
ATOM   3706 H HG13   . ILE A 1 344 ? 127.881 126.757 113.932 1.00 66.22  ? 335 ILE A HG13   1 
ATOM   3707 H HG21   . ILE A 1 344 ? 125.401 124.358 114.597 1.00 66.22  ? 335 ILE A HG21   1 
ATOM   3708 H HG22   . ILE A 1 344 ? 126.149 123.081 114.045 1.00 66.22  ? 335 ILE A HG22   1 
ATOM   3709 H HG23   . ILE A 1 344 ? 126.572 123.703 115.444 1.00 66.22  ? 335 ILE A HG23   1 
ATOM   3710 H HD11   . ILE A 1 344 ? 126.036 127.845 114.528 1.00 66.22  ? 335 ILE A HD11   1 
ATOM   3711 H HD12   . ILE A 1 344 ? 125.504 126.730 113.529 1.00 66.22  ? 335 ILE A HD12   1 
ATOM   3712 H HD13   . ILE A 1 344 ? 125.349 126.530 115.097 1.00 66.22  ? 335 ILE A HD13   1 
ATOM   3713 N N      . GLY A 1 345 ? 128.533 122.424 112.288 1.00 67.79  ? 336 GLY A N      1 
ATOM   3714 C CA     . GLY A 1 345 ? 128.523 121.040 111.839 1.00 67.79  ? 336 GLY A CA     1 
ATOM   3715 C C      . GLY A 1 345 ? 129.877 120.369 111.965 1.00 67.79  ? 336 GLY A C      1 
ATOM   3716 O O      . GLY A 1 345 ? 129.964 119.178 112.289 1.00 67.79  ? 336 GLY A O      1 
ATOM   3717 H H      . GLY A 1 345 ? 128.439 123.006 111.662 1.00 67.79  ? 336 GLY A H      1 
ATOM   3718 H HA2    . GLY A 1 345 ? 127.882 120.537 112.365 1.00 67.79  ? 336 GLY A HA2    1 
ATOM   3719 H HA3    . GLY A 1 345 ? 128.250 121.007 110.909 1.00 67.79  ? 336 GLY A HA3    1 
ATOM   3720 N N      . VAL A 1 346 ? 130.952 121.117 111.696 1.00 68.14  ? 337 VAL A N      1 
ATOM   3721 C CA     . VAL A 1 346 ? 132.282 120.520 111.769 1.00 68.14  ? 337 VAL A CA     1 
ATOM   3722 C C      . VAL A 1 346 ? 132.536 119.973 113.163 1.00 68.14  ? 337 VAL A C      1 
ATOM   3723 O O      . VAL A 1 346 ? 133.294 119.012 113.334 1.00 68.14  ? 337 VAL A O      1 
ATOM   3724 C CB     . VAL A 1 346 ? 133.366 121.537 111.364 1.00 68.14  ? 337 VAL A CB     1 
ATOM   3725 C CG1    . VAL A 1 346 ? 133.814 122.354 112.564 1.00 68.14  ? 337 VAL A CG1    1 
ATOM   3726 C CG2    . VAL A 1 346 ? 134.549 120.823 110.741 1.00 68.14  ? 337 VAL A CG2    1 
ATOM   3727 H H      . VAL A 1 346 ? 130.937 121.947 111.474 1.00 68.14  ? 337 VAL A H      1 
ATOM   3728 H HA     . VAL A 1 346 ? 132.326 119.776 111.149 1.00 68.14  ? 337 VAL A HA     1 
ATOM   3729 H HB     . VAL A 1 346 ? 132.999 122.146 110.704 1.00 68.14  ? 337 VAL A HB     1 
ATOM   3730 H HG11   . VAL A 1 346 ? 134.281 123.142 112.246 1.00 68.14  ? 337 VAL A HG11   1 
ATOM   3731 H HG12   . VAL A 1 346 ? 134.410 121.821 113.112 1.00 68.14  ? 337 VAL A HG12   1 
ATOM   3732 H HG13   . VAL A 1 346 ? 133.035 122.621 113.077 1.00 68.14  ? 337 VAL A HG13   1 
ATOM   3733 H HG21   . VAL A 1 346 ? 135.232 121.475 110.520 1.00 68.14  ? 337 VAL A HG21   1 
ATOM   3734 H HG22   . VAL A 1 346 ? 134.899 120.179 111.377 1.00 68.14  ? 337 VAL A HG22   1 
ATOM   3735 H HG23   . VAL A 1 346 ? 134.255 120.367 109.937 1.00 68.14  ? 337 VAL A HG23   1 
ATOM   3736 N N      . THR A 1 347 ? 131.919 120.573 114.178 1.00 68.41  ? 338 THR A N      1 
ATOM   3737 C CA     . THR A 1 347 ? 132.014 120.065 115.539 1.00 68.41  ? 338 THR A CA     1 
ATOM   3738 C C      . THR A 1 347 ? 130.923 119.055 115.863 1.00 68.41  ? 338 THR A C      1 
ATOM   3739 O O      . THR A 1 347 ? 131.164 118.130 116.647 1.00 68.41  ? 338 THR A O      1 
ATOM   3740 C CB     . THR A 1 347 ? 131.942 121.218 116.538 1.00 68.41  ? 338 THR A CB     1 
ATOM   3741 O OG1    . THR A 1 347 ? 132.930 122.197 116.204 1.00 68.41  ? 338 THR A OG1    1 
ATOM   3742 C CG2    . THR A 1 347 ? 132.193 120.716 117.946 1.00 68.41  ? 338 THR A CG2    1 
ATOM   3743 H H      . THR A 1 347 ? 131.438 121.282 114.103 1.00 68.41  ? 338 THR A H      1 
ATOM   3744 H HA     . THR A 1 347 ? 132.871 119.626 115.652 1.00 68.41  ? 338 THR A HA     1 
ATOM   3745 H HB     . THR A 1 347 ? 131.061 121.622 116.506 1.00 68.41  ? 338 THR A HB     1 
ATOM   3746 H HG1    . THR A 1 347 ? 132.769 122.520 115.446 1.00 68.41  ? 338 THR A HG1    1 
ATOM   3747 H HG21   . THR A 1 347 ? 133.020 120.211 117.974 1.00 68.41  ? 338 THR A HG21   1 
ATOM   3748 H HG22   . THR A 1 347 ? 131.464 120.145 118.231 1.00 68.41  ? 338 THR A HG22   1 
ATOM   3749 H HG23   . THR A 1 347 ? 132.261 121.466 118.558 1.00 68.41  ? 338 THR A HG23   1 
ATOM   3750 N N      . SER A 1 348 ? 129.730 119.215 115.284 1.00 69.06  ? 339 SER A N      1 
ATOM   3751 C CA     . SER A 1 348 ? 128.644 118.279 115.555 1.00 69.06  ? 339 SER A CA     1 
ATOM   3752 C C      . SER A 1 348 ? 129.020 116.871 115.126 1.00 69.06  ? 339 SER A C      1 
ATOM   3753 O O      . SER A 1 348 ? 128.728 115.896 115.830 1.00 69.06  ? 339 SER A O      1 
ATOM   3754 C CB     . SER A 1 348 ? 127.374 118.730 114.837 1.00 69.06  ? 339 SER A CB     1 
ATOM   3755 O OG     . SER A 1 348 ? 127.028 120.055 115.196 1.00 69.06  ? 339 SER A OG     1 
ATOM   3756 H H      . SER A 1 348 ? 129.529 119.848 114.738 1.00 69.06  ? 339 SER A H      1 
ATOM   3757 H HA     . SER A 1 348 ? 128.464 118.268 116.509 1.00 69.06  ? 339 SER A HA     1 
ATOM   3758 H HB2    . SER A 1 348 ? 127.524 118.693 113.879 1.00 69.06  ? 339 SER A HB2    1 
ATOM   3759 H HB3    . SER A 1 348 ? 126.646 118.137 115.082 1.00 69.06  ? 339 SER A HB3    1 
ATOM   3760 H HG     . SER A 1 348 ? 127.646 120.581 114.980 1.00 69.06  ? 339 SER A HG     1 
ATOM   3761 N N      . GLY A 1 349 ? 129.658 116.745 113.968 1.00 68.51  ? 340 GLY A N      1 
ATOM   3762 C CA     . GLY A 1 349 ? 130.058 115.437 113.493 1.00 68.51  ? 340 GLY A CA     1 
ATOM   3763 C C      . GLY A 1 349 ? 130.958 114.719 114.478 1.00 68.51  ? 340 GLY A C      1 
ATOM   3764 O O      . GLY A 1 349 ? 130.670 113.590 114.897 1.00 68.51  ? 340 GLY A O      1 
ATOM   3765 H H      . GLY A 1 349 ? 129.866 117.397 113.446 1.00 68.51  ? 340 GLY A H      1 
ATOM   3766 H HA2    . GLY A 1 349 ? 129.270 114.893 113.343 1.00 68.51  ? 340 GLY A HA2    1 
ATOM   3767 H HA3    . GLY A 1 349 ? 130.533 115.529 112.652 1.00 68.51  ? 340 GLY A HA3    1 
ATOM   3768 N N      . VAL A 1 350 ? 132.047 115.380 114.871 1.00 67.85  ? 341 VAL A N      1 
ATOM   3769 C CA     . VAL A 1 350 ? 132.999 114.747 115.776 1.00 67.85  ? 341 VAL A CA     1 
ATOM   3770 C C      . VAL A 1 350 ? 132.354 114.493 117.129 1.00 67.85  ? 341 VAL A C      1 
ATOM   3771 O O      . VAL A 1 350 ? 132.638 113.486 117.785 1.00 67.85  ? 341 VAL A O      1 
ATOM   3772 C CB     . VAL A 1 350 ? 134.275 115.599 115.907 1.00 67.85  ? 341 VAL A CB     1 
ATOM   3773 C CG1    . VAL A 1 350 ? 134.998 115.670 114.573 1.00 67.85  ? 341 VAL A CG1    1 
ATOM   3774 C CG2    . VAL A 1 350 ? 133.946 116.992 116.421 1.00 67.85  ? 341 VAL A CG2    1 
ATOM   3775 H H      . VAL A 1 350 ? 132.254 116.178 114.628 1.00 67.85  ? 341 VAL A H      1 
ATOM   3776 H HA     . VAL A 1 350 ? 133.256 113.888 115.406 1.00 67.85  ? 341 VAL A HA     1 
ATOM   3777 H HB     . VAL A 1 350 ? 134.870 115.178 116.547 1.00 67.85  ? 341 VAL A HB     1 
ATOM   3778 H HG11   . VAL A 1 350 ? 135.813 116.183 114.684 1.00 67.85  ? 341 VAL A HG11   1 
ATOM   3779 H HG12   . VAL A 1 350 ? 135.210 114.769 114.281 1.00 67.85  ? 341 VAL A HG12   1 
ATOM   3780 H HG13   . VAL A 1 350 ? 134.420 116.101 113.924 1.00 67.85  ? 341 VAL A HG13   1 
ATOM   3781 H HG21   . VAL A 1 350 ? 133.351 117.430 115.795 1.00 67.85  ? 341 VAL A HG21   1 
ATOM   3782 H HG22   . VAL A 1 350 ? 134.770 117.498 116.497 1.00 67.85  ? 341 VAL A HG22   1 
ATOM   3783 H HG23   . VAL A 1 350 ? 133.523 116.923 117.291 1.00 67.85  ? 341 VAL A HG23   1 
ATOM   3784 N N      . GLY A 1 351 ? 131.479 115.396 117.572 1.00 71.26  ? 342 GLY A N      1 
ATOM   3785 C CA     . GLY A 1 351 ? 130.824 115.188 118.851 1.00 71.26  ? 342 GLY A CA     1 
ATOM   3786 C C      . GLY A 1 351 ? 129.963 113.942 118.854 1.00 71.26  ? 342 GLY A C      1 
ATOM   3787 O O      . GLY A 1 351 ? 130.030 113.124 119.775 1.00 71.26  ? 342 GLY A O      1 
ATOM   3788 H H      . GLY A 1 351 ? 131.255 116.117 117.160 1.00 71.26  ? 342 GLY A H      1 
ATOM   3789 H HA2    . GLY A 1 351 ? 131.493 115.103 119.549 1.00 71.26  ? 342 GLY A HA2    1 
ATOM   3790 H HA3    . GLY A 1 351 ? 130.260 115.950 119.055 1.00 71.26  ? 342 GLY A HA3    1 
ATOM   3791 N N      . ARG A 1 352 ? 129.147 113.776 117.813 1.00 71.13  ? 343 ARG A N      1 
ATOM   3792 C CA     . ARG A 1 352 ? 128.328 112.576 117.720 1.00 71.13  ? 343 ARG A CA     1 
ATOM   3793 C C      . ARG A 1 352 ? 129.200 111.332 117.640 1.00 71.13  ? 343 ARG A C      1 
ATOM   3794 O O      . ARG A 1 352 ? 128.924 110.325 118.305 1.00 71.13  ? 343 ARG A O      1 
ATOM   3795 C CB     . ARG A 1 352 ? 127.405 112.668 116.506 1.00 71.13  ? 343 ARG A CB     1 
ATOM   3796 C CG     . ARG A 1 352 ? 126.450 113.848 116.554 1.00 71.13  ? 343 ARG A CG     1 
ATOM   3797 C CD     . ARG A 1 352 ? 125.828 114.124 115.196 1.00 71.13  ? 343 ARG A CD     1 
ATOM   3798 N NE     . ARG A 1 352 ? 125.091 115.381 115.187 1.00 71.13  ? 343 ARG A NE     1 
ATOM   3799 C CZ     . ARG A 1 352 ? 124.548 115.923 114.106 1.00 71.13  ? 343 ARG A CZ     1 
ATOM   3800 N NH1    . ARG A 1 352 ? 124.636 115.341 112.922 1.00 71.13  ? 343 ARG A NH1    1 
ATOM   3801 N NH2    . ARG A 1 352 ? 123.901 117.079 114.217 1.00 71.13  ? 343 ARG A NH2    1 
ATOM   3802 H H      . ARG A 1 352 ? 129.053 114.332 117.164 1.00 71.13  ? 343 ARG A H      1 
ATOM   3803 H HA     . ARG A 1 352 ? 127.775 112.506 118.514 1.00 71.13  ? 343 ARG A HA     1 
ATOM   3804 H HB2    . ARG A 1 352 ? 127.947 112.757 115.707 1.00 71.13  ? 343 ARG A HB2    1 
ATOM   3805 H HB3    . ARG A 1 352 ? 126.874 111.858 116.455 1.00 71.13  ? 343 ARG A HB3    1 
ATOM   3806 H HG2    . ARG A 1 352 ? 125.735 113.653 117.180 1.00 71.13  ? 343 ARG A HG2    1 
ATOM   3807 H HG3    . ARG A 1 352 ? 126.931 114.642 116.834 1.00 71.13  ? 343 ARG A HG3    1 
ATOM   3808 H HD2    . ARG A 1 352 ? 126.529 114.180 114.529 1.00 71.13  ? 343 ARG A HD2    1 
ATOM   3809 H HD3    . ARG A 1 352 ? 125.211 113.408 114.976 1.00 71.13  ? 343 ARG A HD3    1 
ATOM   3810 H HE     . ARG A 1 352 ? 124.890 115.728 115.947 1.00 71.13  ? 343 ARG A HE     1 
ATOM   3811 H HH11   . ARG A 1 352 ? 125.053 114.594 112.838 1.00 71.13  ? 343 ARG A HH11   1 
ATOM   3812 H HH12   . ARG A 1 352 ? 124.277 115.712 112.234 1.00 71.13  ? 343 ARG A HH12   1 
ATOM   3813 H HH21   . ARG A 1 352 ? 123.838 117.465 114.983 1.00 71.13  ? 343 ARG A HH21   1 
ATOM   3814 H HH22   . ARG A 1 352 ? 123.545 117.441 113.522 1.00 71.13  ? 343 ARG A HH22   1 
ATOM   3815 N N      . LEU A 1 353 ? 130.271 111.388 116.842 1.00 71.19  ? 344 LEU A N      1 
ATOM   3816 C CA     . LEU A 1 353 ? 131.133 110.220 116.694 1.00 71.19  ? 344 LEU A CA     1 
ATOM   3817 C C      . LEU A 1 353 ? 131.772 109.833 118.021 1.00 71.19  ? 344 LEU A C      1 
ATOM   3818 O O      . LEU A 1 353 ? 131.841 108.647 118.362 1.00 71.19  ? 344 LEU A O      1 
ATOM   3819 C CB     . LEU A 1 353 ? 132.207 110.490 115.640 1.00 71.19  ? 344 LEU A CB     1 
ATOM   3820 C CG     . LEU A 1 353 ? 131.708 110.616 114.198 1.00 71.19  ? 344 LEU A CG     1 
ATOM   3821 C CD1    . LEU A 1 353 ? 132.844 111.017 113.273 1.00 71.19  ? 344 LEU A CD1    1 
ATOM   3822 C CD2    . LEU A 1 353 ? 131.071 109.315 113.729 1.00 71.19  ? 344 LEU A CD2    1 
ATOM   3823 H H      . LEU A 1 353 ? 130.513 112.076 116.386 1.00 71.19  ? 344 LEU A H      1 
ATOM   3824 H HA     . LEU A 1 353 ? 130.596 109.469 116.397 1.00 71.19  ? 344 LEU A HA     1 
ATOM   3825 H HB2    . LEU A 1 353 ? 132.655 111.320 115.865 1.00 71.19  ? 344 LEU A HB2    1 
ATOM   3826 H HB3    . LEU A 1 353 ? 132.846 109.761 115.662 1.00 71.19  ? 344 LEU A HB3    1 
ATOM   3827 H HG     . LEU A 1 353 ? 131.031 111.309 114.158 1.00 71.19  ? 344 LEU A HG     1 
ATOM   3828 H HD11   . LEU A 1 353 ? 133.238 111.842 113.597 1.00 71.19  ? 344 LEU A HD11   1 
ATOM   3829 H HD12   . LEU A 1 353 ? 132.491 111.148 112.379 1.00 71.19  ? 344 LEU A HD12   1 
ATOM   3830 H HD13   . LEU A 1 353 ? 133.510 110.312 113.267 1.00 71.19  ? 344 LEU A HD13   1 
ATOM   3831 H HD21   . LEU A 1 353 ? 130.847 109.395 112.789 1.00 71.19  ? 344 LEU A HD21   1 
ATOM   3832 H HD22   . LEU A 1 353 ? 131.702 108.590 113.859 1.00 71.19  ? 344 LEU A HD22   1 
ATOM   3833 H HD23   . LEU A 1 353 ? 130.266 109.150 114.245 1.00 71.19  ? 344 LEU A HD23   1 
ATOM   3834 N N      . LEU A 1 354 ? 132.248 110.818 118.783 1.00 76.25  ? 345 LEU A N      1 
ATOM   3835 C CA     . LEU A 1 354 ? 132.886 110.520 120.060 1.00 76.25  ? 345 LEU A CA     1 
ATOM   3836 C C      . LEU A 1 354 ? 131.875 110.007 121.078 1.00 76.25  ? 345 LEU A C      1 
ATOM   3837 O O      . LEU A 1 354 ? 132.149 109.045 121.807 1.00 76.25  ? 345 LEU A O      1 
ATOM   3838 C CB     . LEU A 1 354 ? 133.592 111.767 120.589 1.00 76.25  ? 345 LEU A CB     1 
ATOM   3839 C CG     . LEU A 1 354 ? 134.305 111.627 121.936 1.00 76.25  ? 345 LEU A CG     1 
ATOM   3840 C CD1    . LEU A 1 354 ? 135.428 110.607 121.852 1.00 76.25  ? 345 LEU A CD1    1 
ATOM   3841 C CD2    . LEU A 1 354 ? 134.835 112.974 122.400 1.00 76.25  ? 345 LEU A CD2    1 
ATOM   3842 H H      . LEU A 1 354 ? 132.214 111.654 118.585 1.00 76.25  ? 345 LEU A H      1 
ATOM   3843 H HA     . LEU A 1 354 ? 133.553 109.829 119.925 1.00 76.25  ? 345 LEU A HA     1 
ATOM   3844 H HB2    . LEU A 1 354 ? 134.259 112.037 119.938 1.00 76.25  ? 345 LEU A HB2    1 
ATOM   3845 H HB3    . LEU A 1 354 ? 132.933 112.472 120.684 1.00 76.25  ? 345 LEU A HB3    1 
ATOM   3846 H HG     . LEU A 1 354 ? 133.669 111.317 122.600 1.00 76.25  ? 345 LEU A HG     1 
ATOM   3847 H HD11   . LEU A 1 354 ? 135.898 110.585 122.700 1.00 76.25  ? 345 LEU A HD11   1 
ATOM   3848 H HD12   . LEU A 1 354 ? 135.049 109.735 121.662 1.00 76.25  ? 345 LEU A HD12   1 
ATOM   3849 H HD13   . LEU A 1 354 ? 136.037 110.867 121.143 1.00 76.25  ? 345 LEU A HD13   1 
ATOM   3850 H HD21   . LEU A 1 354 ? 135.250 112.866 123.271 1.00 76.25  ? 345 LEU A HD21   1 
ATOM   3851 H HD22   . LEU A 1 354 ? 135.489 113.294 121.759 1.00 76.25  ? 345 LEU A HD22   1 
ATOM   3852 H HD23   . LEU A 1 354 ? 134.097 113.600 122.461 1.00 76.25  ? 345 LEU A HD23   1 
ATOM   3853 N N      . PHE A 1 355 ? 130.697 110.629 121.148 1.00 75.74  ? 346 PHE A N      1 
ATOM   3854 C CA     . PHE A 1 355 ? 129.744 110.238 122.176 1.00 75.74  ? 346 PHE A CA     1 
ATOM   3855 C C      . PHE A 1 355 ? 129.080 108.903 121.877 1.00 75.74  ? 346 PHE A C      1 
ATOM   3856 O O      . PHE A 1 355 ? 128.657 108.219 122.814 1.00 75.74  ? 346 PHE A O      1 
ATOM   3857 C CB     . PHE A 1 355 ? 128.698 111.331 122.364 1.00 75.74  ? 346 PHE A CB     1 
ATOM   3858 C CG     . PHE A 1 355 ? 129.146 112.422 123.288 1.00 75.74  ? 346 PHE A CG     1 
ATOM   3859 C CD1    . PHE A 1 355 ? 128.921 112.325 124.647 1.00 75.74  ? 346 PHE A CD1    1 
ATOM   3860 C CD2    . PHE A 1 355 ? 129.814 113.531 122.802 1.00 75.74  ? 346 PHE A CD2    1 
ATOM   3861 C CE1    . PHE A 1 355 ? 129.339 113.320 125.501 1.00 75.74  ? 346 PHE A CE1    1 
ATOM   3862 C CE2    . PHE A 1 355 ? 130.233 114.528 123.652 1.00 75.74  ? 346 PHE A CE2    1 
ATOM   3863 C CZ     . PHE A 1 355 ? 129.997 114.423 125.002 1.00 75.74  ? 346 PHE A CZ     1 
ATOM   3864 H H      . PHE A 1 355 ? 130.435 111.260 120.626 1.00 75.74  ? 346 PHE A H      1 
ATOM   3865 H HA     . PHE A 1 355 ? 130.221 110.147 123.014 1.00 75.74  ? 346 PHE A HA     1 
ATOM   3866 H HB2    . PHE A 1 355 ? 128.502 111.731 121.502 1.00 75.74  ? 346 PHE A HB2    1 
ATOM   3867 H HB3    . PHE A 1 355 ? 127.894 110.936 122.736 1.00 75.74  ? 346 PHE A HB3    1 
ATOM   3868 H HD1    . PHE A 1 355 ? 128.477 111.582 124.988 1.00 75.74  ? 346 PHE A HD1    1 
ATOM   3869 H HD2    . PHE A 1 355 ? 129.975 113.608 121.891 1.00 75.74  ? 346 PHE A HD2    1 
ATOM   3870 H HE1    . PHE A 1 355 ? 129.179 113.247 126.413 1.00 75.74  ? 346 PHE A HE1    1 
ATOM   3871 H HE2    . PHE A 1 355 ? 130.677 115.272 123.313 1.00 75.74  ? 346 PHE A HE2    1 
ATOM   3872 H HZ     . PHE A 1 355 ? 130.279 115.096 125.578 1.00 75.74  ? 346 PHE A HZ     1 
ATOM   3873 N N      . GLY A 1 356 ? 129.003 108.498 120.610 1.00 78.62  ? 347 GLY A N      1 
ATOM   3874 C CA     . GLY A 1 356 ? 128.573 107.141 120.326 1.00 78.62  ? 347 GLY A CA     1 
ATOM   3875 C C      . GLY A 1 356 ? 129.447 106.117 121.024 1.00 78.62  ? 347 GLY A C      1 
ATOM   3876 O O      . GLY A 1 356 ? 128.948 105.163 121.624 1.00 78.62  ? 347 GLY A O      1 
ATOM   3877 H H      . GLY A 1 356 ? 129.188 108.977 119.920 1.00 78.62  ? 347 GLY A H      1 
ATOM   3878 H HA2    . GLY A 1 356 ? 127.658 107.020 120.624 1.00 78.62  ? 347 GLY A HA2    1 
ATOM   3879 H HA3    . GLY A 1 356 ? 128.612 106.980 119.370 1.00 78.62  ? 347 GLY A HA3    1 
ATOM   3880 N N      . ARG A 1 357 ? 130.766 106.308 120.962 1.00 80.68  ? 348 ARG A N      1 
ATOM   3881 C CA     . ARG A 1 357 ? 131.682 105.446 121.701 1.00 80.68  ? 348 ARG A CA     1 
ATOM   3882 C C      . ARG A 1 357 ? 131.524 105.634 123.204 1.00 80.68  ? 348 ARG A C      1 
ATOM   3883 O O      . ARG A 1 357 ? 131.516 104.656 123.960 1.00 80.68  ? 348 ARG A O      1 
ATOM   3884 C CB     . ARG A 1 357 ? 133.119 105.740 121.267 1.00 80.68  ? 348 ARG A CB     1 
ATOM   3885 C CG     . ARG A 1 357 ? 134.209 105.114 122.128 1.00 80.68  ? 348 ARG A CG     1 
ATOM   3886 C CD     . ARG A 1 357 ? 134.196 103.604 122.049 1.00 80.68  ? 348 ARG A CD     1 
ATOM   3887 N NE     . ARG A 1 357 ? 135.359 103.025 122.711 1.00 80.68  ? 348 ARG A NE     1 
ATOM   3888 C CZ     . ARG A 1 357 ? 136.556 102.902 122.154 1.00 80.68  ? 348 ARG A CZ     1 
ATOM   3889 N NH1    . ARG A 1 357 ? 136.791 103.312 120.918 1.00 80.68  ? 348 ARG A NH1    1 
ATOM   3890 N NH2    . ARG A 1 357 ? 137.545 102.357 122.856 1.00 80.68  ? 348 ARG A NH2    1 
ATOM   3891 H H      . ARG A 1 357 ? 131.150 106.925 120.503 1.00 80.68  ? 348 ARG A H      1 
ATOM   3892 H HA     . ARG A 1 357 ? 131.487 104.520 121.490 1.00 80.68  ? 348 ARG A HA     1 
ATOM   3893 H HB2    . ARG A 1 357 ? 133.240 105.411 120.362 1.00 80.68  ? 348 ARG A HB2    1 
ATOM   3894 H HB3    . ARG A 1 357 ? 133.253 106.701 121.282 1.00 80.68  ? 348 ARG A HB3    1 
ATOM   3895 H HG2    . ARG A 1 357 ? 135.072 105.420 121.810 1.00 80.68  ? 348 ARG A HG2    1 
ATOM   3896 H HG3    . ARG A 1 357 ? 134.091 105.374 123.055 1.00 80.68  ? 348 ARG A HG3    1 
ATOM   3897 H HD2    . ARG A 1 357 ? 133.399 103.269 122.490 1.00 80.68  ? 348 ARG A HD2    1 
ATOM   3898 H HD3    . ARG A 1 357 ? 134.204 103.330 121.119 1.00 80.68  ? 348 ARG A HD3    1 
ATOM   3899 H HE     . ARG A 1 357 ? 135.271 102.778 123.530 1.00 80.68  ? 348 ARG A HE     1 
ATOM   3900 H HH11   . ARG A 1 357 ? 136.162 103.667 120.453 1.00 80.68  ? 348 ARG A HH11   1 
ATOM   3901 H HH12   . ARG A 1 357 ? 137.576 103.222 120.579 1.00 80.68  ? 348 ARG A HH12   1 
ATOM   3902 H HH21   . ARG A 1 357 ? 137.404 102.087 123.661 1.00 80.68  ? 348 ARG A HH21   1 
ATOM   3903 H HH22   . ARG A 1 357 ? 138.326 102.272 122.506 1.00 80.68  ? 348 ARG A HH22   1 
ATOM   3904 N N      . ILE A 1 358 ? 131.397 106.882 123.656 1.00 80.68  ? 349 ILE A N      1 
ATOM   3905 C CA     . ILE A 1 358 ? 131.397 107.154 125.093 1.00 80.68  ? 349 ILE A CA     1 
ATOM   3906 C C      . ILE A 1 358 ? 130.205 106.493 125.775 1.00 80.68  ? 349 ILE A C      1 
ATOM   3907 O O      . ILE A 1 358 ? 130.324 105.967 126.889 1.00 80.68  ? 349 ILE A O      1 
ATOM   3908 C CB     . ILE A 1 358 ? 131.415 108.673 125.352 1.00 80.68  ? 349 ILE A CB     1 
ATOM   3909 C CG1    . ILE A 1 358 ? 132.751 109.284 124.922 1.00 80.68  ? 349 ILE A CG1    1 
ATOM   3910 C CG2    . ILE A 1 358 ? 131.150 108.966 126.822 1.00 80.68  ? 349 ILE A CG2    1 
ATOM   3911 C CD1    . ILE A 1 358 ? 133.901 108.994 125.866 1.00 80.68  ? 349 ILE A CD1    1 
ATOM   3912 H H      . ILE A 1 358 ? 131.310 107.579 123.159 1.00 80.68  ? 349 ILE A H      1 
ATOM   3913 H HA     . ILE A 1 358 ? 132.202 106.776 125.480 1.00 80.68  ? 349 ILE A HA     1 
ATOM   3914 H HB     . ILE A 1 358 ? 130.707 109.080 124.830 1.00 80.68  ? 349 ILE A HB     1 
ATOM   3915 H HG12   . ILE A 1 358 ? 132.991 108.929 124.052 1.00 80.68  ? 349 ILE A HG12   1 
ATOM   3916 H HG13   . ILE A 1 358 ? 132.650 110.247 124.866 1.00 80.68  ? 349 ILE A HG13   1 
ATOM   3917 H HG21   . ILE A 1 358 ? 130.199 108.895 126.995 1.00 80.68  ? 349 ILE A HG21   1 
ATOM   3918 H HG22   . ILE A 1 358 ? 131.455 109.865 127.022 1.00 80.68  ? 349 ILE A HG22   1 
ATOM   3919 H HG23   . ILE A 1 358 ? 131.636 108.325 127.364 1.00 80.68  ? 349 ILE A HG23   1 
ATOM   3920 H HD11   . ILE A 1 358 ? 134.730 109.269 125.443 1.00 80.68  ? 349 ILE A HD11   1 
ATOM   3921 H HD12   . ILE A 1 358 ? 133.772 109.491 126.689 1.00 80.68  ? 349 ILE A HD12   1 
ATOM   3922 H HD13   . ILE A 1 358 ? 133.928 108.043 126.053 1.00 80.68  ? 349 ILE A HD13   1 
ATOM   3923 N N      . ALA A 1 359 ? 129.041 106.501 125.120 1.00 79.55  ? 350 ALA A N      1 
ATOM   3924 C CA     . ALA A 1 359 ? 127.793 106.189 125.811 1.00 79.55  ? 350 ALA A CA     1 
ATOM   3925 C C      . ALA A 1 359 ? 127.872 104.882 126.588 1.00 79.55  ? 350 ALA A C      1 
ATOM   3926 O O      . ALA A 1 359 ? 127.393 104.799 127.724 1.00 79.55  ? 350 ALA A O      1 
ATOM   3927 C CB     . ALA A 1 359 ? 126.644 106.129 124.805 1.00 79.55  ? 350 ALA A CB     1 
ATOM   3928 H H      . ALA A 1 359 ? 128.950 106.683 124.284 1.00 79.55  ? 350 ALA A H      1 
ATOM   3929 H HA     . ALA A 1 359 ? 127.599 106.900 126.442 1.00 79.55  ? 350 ALA A HA     1 
ATOM   3930 H HB1    . ALA A 1 359 ? 126.565 106.989 124.364 1.00 79.55  ? 350 ALA A HB1    1 
ATOM   3931 H HB2    . ALA A 1 359 ? 125.822 105.922 125.277 1.00 79.55  ? 350 ALA A HB2    1 
ATOM   3932 H HB3    . ALA A 1 359 ? 126.832 105.437 124.151 1.00 79.55  ? 350 ALA A HB3    1 
ATOM   3933 N N      . ASP A 1 360 ? 128.475 103.854 126.003 1.00 84.58  ? 351 ASP A N      1 
ATOM   3934 C CA     . ASP A 1 360 ? 128.403 102.512 126.564 1.00 84.58  ? 351 ASP A CA     1 
ATOM   3935 C C      . ASP A 1 360 ? 129.539 102.189 127.528 1.00 84.58  ? 351 ASP A C      1 
ATOM   3936 O O      . ASP A 1 360 ? 129.526 101.111 128.131 1.00 84.58  ? 351 ASP A O      1 
ATOM   3937 C CB     . ASP A 1 360 ? 128.384 101.474 125.436 1.00 84.58  ? 351 ASP A CB     1 
ATOM   3938 C CG     . ASP A 1 360 ? 128.163 100.062 125.945 1.00 84.58  ? 351 ASP A CG     1 
ATOM   3939 O OD1    . ASP A 1 360 ? 127.109 99.810  126.567 1.00 84.58  ? 351 ASP A OD1    1 
ATOM   3940 O OD2    . ASP A 1 360 ? 129.044 99.205  125.726 1.00 84.58  ? 351 ASP A OD2    1 
ATOM   3941 H H      . ASP A 1 360 ? 128.933 103.907 125.277 1.00 84.58  ? 351 ASP A H      1 
ATOM   3942 H HA     . ASP A 1 360 ? 127.570 102.427 127.051 1.00 84.58  ? 351 ASP A HA     1 
ATOM   3943 H HB2    . ASP A 1 360 ? 127.665 101.688 124.822 1.00 84.58  ? 351 ASP A HB2    1 
ATOM   3944 H HB3    . ASP A 1 360 ? 129.235 101.496 124.972 1.00 84.58  ? 351 ASP A HB3    1 
ATOM   3945 N N      . TYR A 1 361 ? 130.508 103.080 127.707 1.00 84.48  ? 352 TYR A N      1 
ATOM   3946 C CA     . TYR A 1 361 ? 131.641 102.751 128.560 1.00 84.48  ? 352 TYR A CA     1 
ATOM   3947 C C      . TYR A 1 361 ? 131.224 102.744 130.028 1.00 84.48  ? 352 TYR A C      1 
ATOM   3948 O O      . TYR A 1 361 ? 130.284 103.430 130.437 1.00 84.48  ? 352 TYR A O      1 
ATOM   3949 C CB     . TYR A 1 361 ? 132.789 103.731 128.332 1.00 84.48  ? 352 TYR A CB     1 
ATOM   3950 C CG     . TYR A 1 361 ? 134.145 103.062 128.327 1.00 84.48  ? 352 TYR A CG     1 
ATOM   3951 C CD1    . TYR A 1 361 ? 134.509 102.199 127.302 1.00 84.48  ? 352 TYR A CD1    1 
ATOM   3952 C CD2    . TYR A 1 361 ? 135.060 103.290 129.344 1.00 84.48  ? 352 TYR A CD2    1 
ATOM   3953 C CE1    . TYR A 1 361 ? 135.745 101.583 127.292 1.00 84.48  ? 352 TYR A CE1    1 
ATOM   3954 C CE2    . TYR A 1 361 ? 136.299 102.679 129.341 1.00 84.48  ? 352 TYR A CE2    1 
ATOM   3955 C CZ     . TYR A 1 361 ? 136.636 101.827 128.313 1.00 84.48  ? 352 TYR A CZ     1 
ATOM   3956 O OH     . TYR A 1 361 ? 137.869 101.217 128.309 1.00 84.48  ? 352 TYR A OH     1 
ATOM   3957 H H      . TYR A 1 361 ? 130.533 103.865 127.356 1.00 84.48  ? 352 TYR A H      1 
ATOM   3958 H HA     . TYR A 1 361 ? 131.954 101.862 128.335 1.00 84.48  ? 352 TYR A HA     1 
ATOM   3959 H HB2    . TYR A 1 361 ? 132.667 104.167 127.474 1.00 84.48  ? 352 TYR A HB2    1 
ATOM   3960 H HB3    . TYR A 1 361 ? 132.785 104.392 129.042 1.00 84.48  ? 352 TYR A HB3    1 
ATOM   3961 H HD1    . TYR A 1 361 ? 133.910 102.032 126.611 1.00 84.48  ? 352 TYR A HD1    1 
ATOM   3962 H HD2    . TYR A 1 361 ? 134.836 103.865 130.039 1.00 84.48  ? 352 TYR A HD2    1 
ATOM   3963 H HE1    . TYR A 1 361 ? 135.975 101.007 126.598 1.00 84.48  ? 352 TYR A HE1    1 
ATOM   3964 H HE2    . TYR A 1 361 ? 136.902 102.842 130.030 1.00 84.48  ? 352 TYR A HE2    1 
ATOM   3965 H HH     . TYR A 1 361 ? 138.307 101.452 128.986 1.00 84.48  ? 352 TYR A HH     1 
ATOM   3966 N N      . VAL A 1 362 ? 131.953 101.960 130.827 1.00 86.91  ? 353 VAL A N      1 
ATOM   3967 C CA     . VAL A 1 362 ? 131.497 101.651 132.184 1.00 86.91  ? 353 VAL A CA     1 
ATOM   3968 C C      . VAL A 1 362 ? 131.338 102.898 133.046 1.00 86.91  ? 353 VAL A C      1 
ATOM   3969 O O      . VAL A 1 362 ? 130.297 103.033 133.711 1.00 86.91  ? 353 VAL A O      1 
ATOM   3970 C CB     . VAL A 1 362 ? 132.437 100.615 132.829 1.00 86.91  ? 353 VAL A CB     1 
ATOM   3971 C CG1    . VAL A 1 362 ? 132.000 100.316 134.256 1.00 86.91  ? 353 VAL A CG1    1 
ATOM   3972 C CG2    . VAL A 1 362 ? 132.471 99.341  132.001 1.00 86.91  ? 353 VAL A CG2    1 
ATOM   3973 H H      . VAL A 1 362 ? 132.704 101.601 130.610 1.00 86.91  ? 353 VAL A H      1 
ATOM   3974 H HA     . VAL A 1 362 ? 130.625 101.233 132.120 1.00 86.91  ? 353 VAL A HA     1 
ATOM   3975 H HB     . VAL A 1 362 ? 133.337 100.975 132.861 1.00 86.91  ? 353 VAL A HB     1 
ATOM   3976 H HG11   . VAL A 1 362 ? 132.231 101.067 134.825 1.00 86.91  ? 353 VAL A HG11   1 
ATOM   3977 H HG12   . VAL A 1 362 ? 132.459 99.519  134.564 1.00 86.91  ? 353 VAL A HG12   1 
ATOM   3978 H HG13   . VAL A 1 362 ? 131.042 100.170 134.268 1.00 86.91  ? 353 VAL A HG13   1 
ATOM   3979 H HG21   . VAL A 1 362 ? 133.013 98.680  132.459 1.00 86.91  ? 353 VAL A HG21   1 
ATOM   3980 H HG22   . VAL A 1 362 ? 131.564 99.011  131.896 1.00 86.91  ? 353 VAL A HG22   1 
ATOM   3981 H HG23   . VAL A 1 362 ? 132.854 99.537  131.132 1.00 86.91  ? 353 VAL A HG23   1 
ATOM   3982 N N      . PRO A 1 363 ? 132.295 103.832 133.091 1.00 88.91  ? 354 PRO A N      1 
ATOM   3983 C CA     . PRO A 1 363 ? 132.205 104.929 134.072 1.00 88.91  ? 354 PRO A CA     1 
ATOM   3984 C C      . PRO A 1 363 ? 130.974 105.811 133.921 1.00 88.91  ? 354 PRO A C      1 
ATOM   3985 O O      . PRO A 1 363 ? 130.673 106.570 134.852 1.00 88.91  ? 354 PRO A O      1 
ATOM   3986 C CB     . PRO A 1 363 ? 133.490 105.732 133.825 1.00 88.91  ? 354 PRO A CB     1 
ATOM   3987 C CG     . PRO A 1 363 ? 134.422 104.774 133.173 1.00 88.91  ? 354 PRO A CG     1 
ATOM   3988 C CD     . PRO A 1 363 ? 133.557 103.881 132.335 1.00 88.91  ? 354 PRO A CD     1 
ATOM   3989 H HA     . PRO A 1 363 ? 132.227 104.571 134.972 1.00 88.91  ? 354 PRO A HA     1 
ATOM   3990 H HB2    . PRO A 1 363 ? 133.300 106.481 133.238 1.00 88.91  ? 354 PRO A HB2    1 
ATOM   3991 H HB3    . PRO A 1 363 ? 133.852 106.041 134.670 1.00 88.91  ? 354 PRO A HB3    1 
ATOM   3992 H HG2    . PRO A 1 363 ? 135.052 105.260 132.618 1.00 88.91  ? 354 PRO A HG2    1 
ATOM   3993 H HG3    . PRO A 1 363 ? 134.887 104.261 133.851 1.00 88.91  ? 354 PRO A HG3    1 
ATOM   3994 H HD2    . PRO A 1 363 ? 133.410 104.278 131.462 1.00 88.91  ? 354 PRO A HD2    1 
ATOM   3995 H HD3    . PRO A 1 363 ? 133.952 102.999 132.264 1.00 88.91  ? 354 PRO A HD3    1 
ATOM   3996 N N      . GLY A 1 364 ? 130.264 105.751 132.795 1.00 85.71  ? 355 GLY A N      1 
ATOM   3997 C CA     . GLY A 1 364 ? 129.116 106.614 132.591 1.00 85.71  ? 355 GLY A CA     1 
ATOM   3998 C C      . GLY A 1 364 ? 127.944 105.959 131.887 1.00 85.71  ? 355 GLY A C      1 
ATOM   3999 O O      . GLY A 1 364 ? 127.012 106.646 131.460 1.00 85.71  ? 355 GLY A O      1 
ATOM   4000 H H      . GLY A 1 364 ? 130.430 105.219 132.139 1.00 85.71  ? 355 GLY A H      1 
ATOM   4001 H HA2    . GLY A 1 364 ? 128.801 106.935 133.451 1.00 85.71  ? 355 GLY A HA2    1 
ATOM   4002 H HA3    . GLY A 1 364 ? 129.390 107.382 132.066 1.00 85.71  ? 355 GLY A HA3    1 
ATOM   4003 N N      . VAL A 1 365 ? 127.972 104.632 131.762 1.00 85.50  ? 356 VAL A N      1 
ATOM   4004 C CA     . VAL A 1 365 ? 126.892 103.932 131.075 1.00 85.50  ? 356 VAL A CA     1 
ATOM   4005 C C      . VAL A 1 365 ? 125.781 103.499 132.022 1.00 85.50  ? 356 VAL A C      1 
ATOM   4006 O O      . VAL A 1 365 ? 124.697 103.126 131.558 1.00 85.50  ? 356 VAL A O      1 
ATOM   4007 C CB     . VAL A 1 365 ? 127.431 102.702 130.324 1.00 85.50  ? 356 VAL A CB     1 
ATOM   4008 C CG1    . VAL A 1 365 ? 128.045 101.700 131.295 1.00 85.50  ? 356 VAL A CG1    1 
ATOM   4009 C CG2    . VAL A 1 365 ? 126.327 102.042 129.505 1.00 85.50  ? 356 VAL A CG2    1 
ATOM   4010 H H      . VAL A 1 365 ? 128.597 104.127 132.064 1.00 85.50  ? 356 VAL A H      1 
ATOM   4011 H HA     . VAL A 1 365 ? 126.502 104.529 130.417 1.00 85.50  ? 356 VAL A HA     1 
ATOM   4012 H HB     . VAL A 1 365 ? 128.121 102.988 129.708 1.00 85.50  ? 356 VAL A HB     1 
ATOM   4013 H HG11   . VAL A 1 365 ? 128.522 101.025 130.788 1.00 85.50  ? 356 VAL A HG11   1 
ATOM   4014 H HG12   . VAL A 1 365 ? 128.658 102.160 131.888 1.00 85.50  ? 356 VAL A HG12   1 
ATOM   4015 H HG13   . VAL A 1 365 ? 127.338 101.284 131.812 1.00 85.50  ? 356 VAL A HG13   1 
ATOM   4016 H HG21   . VAL A 1 365 ? 126.733 101.436 128.866 1.00 85.50  ? 356 VAL A HG21   1 
ATOM   4017 H HG22   . VAL A 1 365 ? 125.742 101.546 130.097 1.00 85.50  ? 356 VAL A HG22   1 
ATOM   4018 H HG23   . VAL A 1 365 ? 125.826 102.729 129.038 1.00 85.50  ? 356 VAL A HG23   1 
ATOM   4019 N N      . LYS A 1 366 ? 126.010 103.550 133.334 1.00 84.44  ? 357 LYS A N      1 
ATOM   4020 C CA     . LYS A 1 366 ? 125.053 102.975 134.276 1.00 84.44  ? 357 LYS A CA     1 
ATOM   4021 C C      . LYS A 1 366 ? 123.655 103.550 134.072 1.00 84.44  ? 357 LYS A C      1 
ATOM   4022 O O      . LYS A 1 366 ? 122.681 102.806 133.914 1.00 84.44  ? 357 LYS A O      1 
ATOM   4023 C CB     . LYS A 1 366 ? 125.534 103.212 135.709 1.00 84.44  ? 357 LYS A CB     1 
ATOM   4024 C CG     . LYS A 1 366 ? 126.957 102.733 135.977 1.00 84.44  ? 357 LYS A CG     1 
ATOM   4025 C CD     . LYS A 1 366 ? 127.137 101.262 135.636 1.00 84.44  ? 357 LYS A CD     1 
ATOM   4026 C CE     . LYS A 1 366 ? 128.538 100.783 135.979 1.00 84.44  ? 357 LYS A CE     1 
ATOM   4027 N NZ     . LYS A 1 366 ? 128.712 99.326  135.721 1.00 84.44  ? 357 LYS A NZ     1 
ATOM   4028 H H      . LYS A 1 366 ? 126.701 103.908 133.699 1.00 84.44  ? 357 LYS A H      1 
ATOM   4029 H HA     . LYS A 1 366 ? 125.002 102.017 134.129 1.00 84.44  ? 357 LYS A HA     1 
ATOM   4030 H HB2    . LYS A 1 366 ? 125.502 104.163 135.895 1.00 84.44  ? 357 LYS A HB2    1 
ATOM   4031 H HB3    . LYS A 1 366 ? 124.944 102.739 136.316 1.00 84.44  ? 357 LYS A HB3    1 
ATOM   4032 H HG2    . LYS A 1 366 ? 127.577 103.248 135.438 1.00 84.44  ? 357 LYS A HG2    1 
ATOM   4033 H HG3    . LYS A 1 366 ? 127.157 102.851 136.919 1.00 84.44  ? 357 LYS A HG3    1 
ATOM   4034 H HD2    . LYS A 1 366 ? 126.501 100.734 136.145 1.00 84.44  ? 357 LYS A HD2    1 
ATOM   4035 H HD3    . LYS A 1 366 ? 127.000 101.131 134.685 1.00 84.44  ? 357 LYS A HD3    1 
ATOM   4036 H HE2    . LYS A 1 366 ? 129.181 101.264 135.435 1.00 84.44  ? 357 LYS A HE2    1 
ATOM   4037 H HE3    . LYS A 1 366 ? 128.708 100.945 136.920 1.00 84.44  ? 357 LYS A HE3    1 
ATOM   4038 H HZ1    . LYS A 1 366 ? 129.547 99.082  135.908 1.00 84.44  ? 357 LYS A HZ1    1 
ATOM   4039 H HZ2    . LYS A 1 366 ? 128.153 98.858  136.232 1.00 84.44  ? 357 LYS A HZ2    1 
ATOM   4040 H HZ3    . LYS A 1 366 ? 128.542 99.146  134.866 1.00 84.44  ? 357 LYS A HZ3    1 
ATOM   4041 N N      . LYS A 1 367 ? 123.537 104.879 134.066 1.00 77.28  ? 358 LYS A N      1 
ATOM   4042 C CA     . LYS A 1 367 ? 122.253 105.525 133.790 1.00 77.28  ? 358 LYS A CA     1 
ATOM   4043 C C      . LYS A 1 367 ? 122.560 106.947 133.325 1.00 77.28  ? 358 LYS A C      1 
ATOM   4044 O O      . LYS A 1 367 ? 123.012 107.774 134.121 1.00 77.28  ? 358 LYS A O      1 
ATOM   4045 C CB     . LYS A 1 367 ? 121.351 105.517 135.014 1.00 77.28  ? 358 LYS A CB     1 
ATOM   4046 C CG     . LYS A 1 367 ? 119.982 106.141 134.785 1.00 77.28  ? 358 LYS A CG     1 
ATOM   4047 C CD     . LYS A 1 367 ? 119.279 105.534 133.579 1.00 77.28  ? 358 LYS A CD     1 
ATOM   4048 C CE     . LYS A 1 367 ? 117.817 105.936 133.523 1.00 77.28  ? 358 LYS A CE     1 
ATOM   4049 N NZ     . LYS A 1 367 ? 117.024 105.290 134.603 1.00 77.28  ? 358 LYS A NZ     1 
ATOM   4050 H H      . LYS A 1 367 ? 124.182 105.427 134.221 1.00 77.28  ? 358 LYS A H      1 
ATOM   4051 H HA     . LYS A 1 367 ? 121.810 105.052 133.069 1.00 77.28  ? 358 LYS A HA     1 
ATOM   4052 H HB2    . LYS A 1 367 ? 121.214 104.598 135.295 1.00 77.28  ? 358 LYS A HB2    1 
ATOM   4053 H HB3    . LYS A 1 367 ? 121.786 106.015 135.724 1.00 77.28  ? 358 LYS A HB3    1 
ATOM   4054 H HG2    . LYS A 1 367 ? 119.428 105.989 135.566 1.00 77.28  ? 358 LYS A HG2    1 
ATOM   4055 H HG3    . LYS A 1 367 ? 120.086 107.092 134.629 1.00 77.28  ? 358 LYS A HG3    1 
ATOM   4056 H HD2    . LYS A 1 367 ? 119.708 105.847 132.767 1.00 77.28  ? 358 LYS A HD2    1 
ATOM   4057 H HD3    . LYS A 1 367 ? 119.326 104.567 133.633 1.00 77.28  ? 358 LYS A HD3    1 
ATOM   4058 H HE2    . LYS A 1 367 ? 117.747 106.898 133.630 1.00 77.28  ? 358 LYS A HE2    1 
ATOM   4059 H HE3    . LYS A 1 367 ? 117.445 105.666 132.669 1.00 77.28  ? 358 LYS A HE3    1 
ATOM   4060 H HZ1    . LYS A 1 367 ? 117.064 104.405 134.521 1.00 77.28  ? 358 LYS A HZ1    1 
ATOM   4061 H HZ2    . LYS A 1 367 ? 116.174 105.547 134.551 1.00 77.28  ? 358 LYS A HZ2    1 
ATOM   4062 H HZ3    . LYS A 1 367 ? 117.348 105.522 135.399 1.00 77.28  ? 358 LYS A HZ3    1 
ATOM   4063 N N      . VAL A 1 368 ? 122.304 107.217 132.049 1.00 73.32  ? 359 VAL A N      1 
ATOM   4064 C CA     . VAL A 1 368 ? 122.791 108.439 131.416 1.00 73.32  ? 359 VAL A CA     1 
ATOM   4065 C C      . VAL A 1 368 ? 121.781 109.561 131.618 1.00 73.32  ? 359 VAL A C      1 
ATOM   4066 O O      . VAL A 1 368 ? 120.631 109.469 131.176 1.00 73.32  ? 359 VAL A O      1 
ATOM   4067 C CB     . VAL A 1 368 ? 123.072 108.215 129.924 1.00 73.32  ? 359 VAL A CB     1 
ATOM   4068 C CG1    . VAL A 1 368 ? 121.789 107.870 129.172 1.00 73.32  ? 359 VAL A CG1    1 
ATOM   4069 C CG2    . VAL A 1 368 ? 123.758 109.441 129.333 1.00 73.32  ? 359 VAL A CG2    1 
ATOM   4070 H H      . VAL A 1 368 ? 121.850 106.706 131.527 1.00 73.32  ? 359 VAL A H      1 
ATOM   4071 H HA     . VAL A 1 368 ? 123.621 108.703 131.843 1.00 73.32  ? 359 VAL A HA     1 
ATOM   4072 H HB     . VAL A 1 368 ? 123.679 107.464 129.831 1.00 73.32  ? 359 VAL A HB     1 
ATOM   4073 H HG11   . VAL A 1 368 ? 121.438 108.666 128.745 1.00 73.32  ? 359 VAL A HG11   1 
ATOM   4074 H HG12   . VAL A 1 368 ? 121.135 107.521 129.797 1.00 73.32  ? 359 VAL A HG12   1 
ATOM   4075 H HG13   . VAL A 1 368 ? 121.991 107.198 128.503 1.00 73.32  ? 359 VAL A HG13   1 
ATOM   4076 H HG21   . VAL A 1 368 ? 124.500 109.149 128.779 1.00 73.32  ? 359 VAL A HG21   1 
ATOM   4077 H HG22   . VAL A 1 368 ? 124.088 109.996 130.056 1.00 73.32  ? 359 VAL A HG22   1 
ATOM   4078 H HG23   . VAL A 1 368 ? 123.126 109.942 128.796 1.00 73.32  ? 359 VAL A HG23   1 
ATOM   4079 N N      . TYR A 1 369 ? 122.215 110.627 132.291 1.00 74.61  ? 360 TYR A N      1 
ATOM   4080 C CA     . TYR A 1 369 ? 121.473 111.879 132.365 1.00 74.61  ? 360 TYR A CA     1 
ATOM   4081 C C      . TYR A 1 369 ? 122.303 113.042 131.832 1.00 74.61  ? 360 TYR A C      1 
ATOM   4082 O O      . TYR A 1 369 ? 122.059 114.197 132.193 1.00 74.61  ? 360 TYR A O      1 
ATOM   4083 C CB     . TYR A 1 369 ? 121.028 112.155 133.801 1.00 74.61  ? 360 TYR A CB     1 
ATOM   4084 C CG     . TYR A 1 369 ? 122.169 112.296 134.781 1.00 74.61  ? 360 TYR A CG     1 
ATOM   4085 C CD1    . TYR A 1 369 ? 122.667 111.194 135.459 1.00 74.61  ? 360 TYR A CD1    1 
ATOM   4086 C CD2    . TYR A 1 369 ? 122.745 113.532 135.030 1.00 74.61  ? 360 TYR A CD2    1 
ATOM   4087 C CE1    . TYR A 1 369 ? 123.706 111.319 136.357 1.00 74.61  ? 360 TYR A CE1    1 
ATOM   4088 C CE2    . TYR A 1 369 ? 123.785 113.668 135.925 1.00 74.61  ? 360 TYR A CE2    1 
ATOM   4089 C CZ     . TYR A 1 369 ? 124.262 112.559 136.586 1.00 74.61  ? 360 TYR A CZ     1 
ATOM   4090 O OH     . TYR A 1 369 ? 125.300 112.691 137.479 1.00 74.61  ? 360 TYR A OH     1 
ATOM   4091 H H      . TYR A 1 369 ? 122.957 110.646 132.725 1.00 74.61  ? 360 TYR A H      1 
ATOM   4092 H HA     . TYR A 1 369 ? 120.676 111.808 131.817 1.00 74.61  ? 360 TYR A HA     1 
ATOM   4093 H HB2    . TYR A 1 369 ? 120.513 112.977 133.821 1.00 74.61  ? 360 TYR A HB2    1 
ATOM   4094 H HD1    . TYR A 1 369 ? 122.293 110.356 135.307 1.00 74.61  ? 360 TYR A HD1    1 
ATOM   4095 H HD2    . TYR A 1 369 ? 122.424 114.283 134.586 1.00 74.61  ? 360 TYR A HD2    1 
ATOM   4096 H HE1    . TYR A 1 369 ? 124.031 110.571 136.804 1.00 74.61  ? 360 TYR A HE1    1 
ATOM   4097 H HE2    . TYR A 1 369 ? 124.161 114.504 136.081 1.00 74.61  ? 360 TYR A HE2    1 
ATOM   4098 H HH     . TYR A 1 369 ? 125.546 113.493 137.516 1.00 74.61  ? 360 TYR A HH     1 
ATOM   4099 N N      . LEU A 1 370 ? 123.285 112.750 130.975 1.00 72.89  ? 361 LEU A N      1 
ATOM   4100 C CA     . LEU A 1 370 ? 124.169 113.783 130.449 1.00 72.89  ? 361 LEU A CA     1 
ATOM   4101 C C      . LEU A 1 370 ? 123.435 114.762 129.547 1.00 72.89  ? 361 LEU A C      1 
ATOM   4102 O O      . LEU A 1 370 ? 123.990 115.813 129.203 1.00 72.89  ? 361 LEU A O      1 
ATOM   4103 C CB     . LEU A 1 370 ? 125.321 113.127 129.687 1.00 72.89  ? 361 LEU A CB     1 
ATOM   4104 C CG     . LEU A 1 370 ? 126.520 114.006 129.339 1.00 72.89  ? 361 LEU A CG     1 
ATOM   4105 C CD1    . LEU A 1 370 ? 127.182 114.532 130.600 1.00 72.89  ? 361 LEU A CD1    1 
ATOM   4106 C CD2    . LEU A 1 370 ? 127.513 113.222 128.498 1.00 72.89  ? 361 LEU A CD2    1 
ATOM   4107 H H      . LEU A 1 370 ? 123.458 111.960 130.684 1.00 72.89  ? 361 LEU A H      1 
ATOM   4108 H HA     . LEU A 1 370 ? 124.542 114.283 131.191 1.00 72.89  ? 361 LEU A HA     1 
ATOM   4109 H HB2    . LEU A 1 370 ? 125.655 112.391 130.223 1.00 72.89  ? 361 LEU A HB2    1 
ATOM   4110 H HB3    . LEU A 1 370 ? 124.970 112.780 128.852 1.00 72.89  ? 361 LEU A HB3    1 
ATOM   4111 H HG     . LEU A 1 370 ? 126.217 114.765 128.816 1.00 72.89  ? 361 LEU A HG     1 
ATOM   4112 H HD11   . LEU A 1 370 ? 127.309 113.795 131.218 1.00 72.89  ? 361 LEU A HD11   1 
ATOM   4113 H HD12   . LEU A 1 370 ? 128.040 114.918 130.368 1.00 72.89  ? 361 LEU A HD12   1 
ATOM   4114 H HD13   . LEU A 1 370 ? 126.611 115.204 131.002 1.00 72.89  ? 361 LEU A HD13   1 
ATOM   4115 H HD21   . LEU A 1 370 ? 127.806 112.445 128.999 1.00 72.89  ? 361 LEU A HD21   1 
ATOM   4116 H HD22   . LEU A 1 370 ? 127.079 112.942 127.677 1.00 72.89  ? 361 LEU A HD22   1 
ATOM   4117 H HD23   . LEU A 1 370 ? 128.272 113.790 128.294 1.00 72.89  ? 361 LEU A HD23   1 
ATOM   4118 N N      . GLN A 1 371 ? 122.209 114.434 129.138 1.00 68.24  ? 362 GLN A N      1 
ATOM   4119 C CA     . GLN A 1 371 ? 121.419 115.393 128.380 1.00 68.24  ? 362 GLN A CA     1 
ATOM   4120 C C      . GLN A 1 371 ? 121.160 116.653 129.191 1.00 68.24  ? 362 GLN A C      1 
ATOM   4121 O O      . GLN A 1 371 ? 121.023 117.740 128.620 1.00 68.24  ? 362 GLN A O      1 
ATOM   4122 C CB     . GLN A 1 371 ? 120.104 114.755 127.938 1.00 68.24  ? 362 GLN A CB     1 
ATOM   4123 C CG     . GLN A 1 371 ? 120.270 113.742 126.822 1.00 68.24  ? 362 GLN A CG     1 
ATOM   4124 C CD     . GLN A 1 371 ? 118.947 113.245 126.287 1.00 68.24  ? 362 GLN A CD     1 
ATOM   4125 O OE1    . GLN A 1 371 ? 117.939 113.246 126.992 1.00 68.24  ? 362 GLN A OE1    1 
ATOM   4126 N NE2    . GLN A 1 371 ? 118.941 112.820 125.031 1.00 68.24  ? 362 GLN A NE2    1 
ATOM   4127 H H      . GLN A 1 371 ? 121.822 113.680 129.281 1.00 68.24  ? 362 GLN A H      1 
ATOM   4128 H HA     . GLN A 1 371 ? 121.910 115.646 127.583 1.00 68.24  ? 362 GLN A HA     1 
ATOM   4129 H HB2    . GLN A 1 371 ? 119.706 114.299 128.696 1.00 68.24  ? 362 GLN A HB2    1 
ATOM   4130 H HB3    . GLN A 1 371 ? 119.508 115.451 127.622 1.00 68.24  ? 362 GLN A HB3    1 
ATOM   4131 H HG2    . GLN A 1 371 ? 120.754 114.155 126.090 1.00 68.24  ? 362 GLN A HG2    1 
ATOM   4132 H HG3    . GLN A 1 371 ? 120.765 112.979 127.158 1.00 68.24  ? 362 GLN A HG3    1 
ATOM   4133 H HE21   . GLN A 1 371 ? 119.666 112.836 124.569 1.00 68.24  ? 362 GLN A HE21   1 
ATOM   4134 H HE22   . GLN A 1 371 ? 118.213 112.527 124.679 1.00 68.24  ? 362 GLN A HE22   1 
ATOM   4135 N N      . VAL A 1 372 ? 121.105 116.536 130.518 1.00 68.00  ? 363 VAL A N      1 
ATOM   4136 C CA     . VAL A 1 372 ? 120.974 117.724 131.358 1.00 68.00  ? 363 VAL A CA     1 
ATOM   4137 C C      . VAL A 1 372 ? 122.189 118.626 131.180 1.00 68.00  ? 363 VAL A C      1 
ATOM   4138 O O      . VAL A 1 372 ? 122.065 119.848 131.021 1.00 68.00  ? 363 VAL A O      1 
ATOM   4139 C CB     . VAL A 1 372 ? 120.784 117.322 132.830 1.00 68.00  ? 363 VAL A CB     1 
ATOM   4140 C CG1    . VAL A 1 372 ? 120.736 118.555 133.716 1.00 68.00  ? 363 VAL A CG1    1 
ATOM   4141 C CG2    . VAL A 1 372 ? 119.523 116.491 132.995 1.00 68.00  ? 363 VAL A CG2    1 
ATOM   4142 H H      . VAL A 1 372 ? 121.140 115.793 130.950 1.00 68.00  ? 363 VAL A H      1 
ATOM   4143 H HA     . VAL A 1 372 ? 120.189 118.222 131.080 1.00 68.00  ? 363 VAL A HA     1 
ATOM   4144 H HB     . VAL A 1 372 ? 121.538 116.780 133.110 1.00 68.00  ? 363 VAL A HB     1 
ATOM   4145 H HG11   . VAL A 1 372 ? 121.631 118.917 133.807 1.00 68.00  ? 363 VAL A HG11   1 
ATOM   4146 H HG12   . VAL A 1 372 ? 120.394 118.303 134.587 1.00 68.00  ? 363 VAL A HG12   1 
ATOM   4147 H HG13   . VAL A 1 372 ? 120.150 119.212 133.309 1.00 68.00  ? 363 VAL A HG13   1 
ATOM   4148 H HG21   . VAL A 1 372 ? 119.734 115.700 133.514 1.00 68.00  ? 363 VAL A HG21   1 
ATOM   4149 H HG22   . VAL A 1 372 ? 119.190 116.234 132.122 1.00 68.00  ? 363 VAL A HG22   1 
ATOM   4150 H HG23   . VAL A 1 372 ? 118.856 117.020 133.460 1.00 68.00  ? 363 VAL A HG23   1 
ATOM   4151 N N      . LEU A 1 373 ? 123.385 118.033 131.196 1.00 68.05  ? 364 LEU A N      1 
ATOM   4152 C CA     . LEU A 1 373 ? 124.600 118.810 130.977 1.00 68.05  ? 364 LEU A CA     1 
ATOM   4153 C C      . LEU A 1 373 ? 124.606 119.430 129.589 1.00 68.05  ? 364 LEU A C      1 
ATOM   4154 O O      . LEU A 1 373 ? 124.994 120.593 129.415 1.00 68.05  ? 364 LEU A O      1 
ATOM   4155 C CB     . LEU A 1 373 ? 125.827 117.918 131.164 1.00 68.05  ? 364 LEU A CB     1 
ATOM   4156 C CG     . LEU A 1 373 ? 127.184 118.621 131.128 1.00 68.05  ? 364 LEU A CG     1 
ATOM   4157 C CD1    . LEU A 1 373 ? 127.344 119.532 132.333 1.00 68.05  ? 364 LEU A CD1    1 
ATOM   4158 C CD2    . LEU A 1 373 ? 128.308 117.603 131.066 1.00 68.05  ? 364 LEU A CD2    1 
ATOM   4159 H H      . LEU A 1 373 ? 123.515 117.194 131.331 1.00 68.05  ? 364 LEU A H      1 
ATOM   4160 H HA     . LEU A 1 373 ? 124.642 119.526 131.630 1.00 68.05  ? 364 LEU A HA     1 
ATOM   4161 H HB2    . LEU A 1 373 ? 125.753 117.473 132.023 1.00 68.05  ? 364 LEU A HB2    1 
ATOM   4162 H HB3    . LEU A 1 373 ? 125.828 117.255 130.457 1.00 68.05  ? 364 LEU A HB3    1 
ATOM   4163 H HG     . LEU A 1 373 ? 127.234 119.169 130.330 1.00 68.05  ? 364 LEU A HG     1 
ATOM   4164 H HD11   . LEU A 1 373 ? 128.253 119.869 132.354 1.00 68.05  ? 364 LEU A HD11   1 
ATOM   4165 H HD12   . LEU A 1 373 ? 126.719 120.270 132.257 1.00 68.05  ? 364 LEU A HD12   1 
ATOM   4166 H HD13   . LEU A 1 373 ? 127.162 119.023 133.138 1.00 68.05  ? 364 LEU A HD13   1 
ATOM   4167 H HD21   . LEU A 1 373 ? 129.157 118.062 131.167 1.00 68.05  ? 364 LEU A HD21   1 
ATOM   4168 H HD22   . LEU A 1 373 ? 128.193 116.959 131.782 1.00 68.05  ? 364 LEU A HD22   1 
ATOM   4169 H HD23   . LEU A 1 373 ? 128.277 117.152 130.207 1.00 68.05  ? 364 LEU A HD23   1 
ATOM   4170 N N      . SER A 1 374 ? 124.192 118.659 128.584 1.00 68.21  ? 365 SER A N      1 
ATOM   4171 C CA     . SER A 1 374 ? 124.146 119.177 127.222 1.00 68.21  ? 365 SER A CA     1 
ATOM   4172 C C      . SER A 1 374 ? 123.234 120.393 127.134 1.00 68.21  ? 365 SER A C      1 
ATOM   4173 O O      . SER A 1 374 ? 123.601 121.422 126.553 1.00 68.21  ? 365 SER A O      1 
ATOM   4174 C CB     . SER A 1 374 ? 123.674 118.081 126.268 1.00 68.21  ? 365 SER A CB     1 
ATOM   4175 O OG     . SER A 1 374 ? 123.536 118.575 124.948 1.00 68.21  ? 365 SER A OG     1 
ATOM   4176 H H      . SER A 1 374 ? 123.936 117.842 128.665 1.00 68.21  ? 365 SER A H      1 
ATOM   4177 H HA     . SER A 1 374 ? 125.038 119.448 126.954 1.00 68.21  ? 365 SER A HA     1 
ATOM   4178 H HB2    . SER A 1 374 ? 124.324 117.361 126.269 1.00 68.21  ? 365 SER A HB2    1 
ATOM   4179 H HB3    . SER A 1 374 ? 122.814 117.751 126.571 1.00 68.21  ? 365 SER A HB3    1 
ATOM   4180 H HG     . SER A 1 374 ? 124.292 118.737 124.621 1.00 68.21  ? 365 SER A HG     1 
ATOM   4181 N N      . PHE A 1 375 ? 122.034 120.291 127.709 1.00 64.83  ? 366 PHE A N      1 
ATOM   4182 C CA     . PHE A 1 375 ? 121.106 121.414 127.683 1.00 64.83  ? 366 PHE A CA     1 
ATOM   4183 C C      . PHE A 1 375 ? 121.677 122.611 128.425 1.00 64.83  ? 366 PHE A C      1 
ATOM   4184 O O      . PHE A 1 375 ? 121.572 123.749 127.954 1.00 64.83  ? 366 PHE A O      1 
ATOM   4185 C CB     . PHE A 1 375 ? 119.762 121.002 128.288 1.00 64.83  ? 366 PHE A CB     1 
ATOM   4186 C CG     . PHE A 1 375 ? 118.950 120.082 127.414 1.00 64.83  ? 366 PHE A CG     1 
ATOM   4187 C CD1    . PHE A 1 375 ? 118.945 120.223 126.036 1.00 64.83  ? 366 PHE A CD1    1 
ATOM   4188 C CD2    . PHE A 1 375 ? 118.185 119.077 127.978 1.00 64.83  ? 366 PHE A CD2    1 
ATOM   4189 C CE1    . PHE A 1 375 ? 118.198 119.379 125.240 1.00 64.83  ? 366 PHE A CE1    1 
ATOM   4190 C CE2    . PHE A 1 375 ? 117.437 118.230 127.186 1.00 64.83  ? 366 PHE A CE2    1 
ATOM   4191 C CZ     . PHE A 1 375 ? 117.443 118.382 125.816 1.00 64.83  ? 366 PHE A CZ     1 
ATOM   4192 H H      . PHE A 1 375 ? 121.741 119.592 128.115 1.00 64.83  ? 366 PHE A H      1 
ATOM   4193 H HA     . PHE A 1 375 ? 120.968 121.687 126.764 1.00 64.83  ? 366 PHE A HA     1 
ATOM   4194 H HB2    . PHE A 1 375 ? 119.926 120.544 129.127 1.00 64.83  ? 366 PHE A HB2    1 
ATOM   4195 H HB3    . PHE A 1 375 ? 119.235 121.800 128.447 1.00 64.83  ? 366 PHE A HB3    1 
ATOM   4196 H HD1    . PHE A 1 375 ? 119.452 120.894 125.640 1.00 64.83  ? 366 PHE A HD1    1 
ATOM   4197 H HD2    . PHE A 1 375 ? 118.177 118.969 128.902 1.00 64.83  ? 366 PHE A HD2    1 
ATOM   4198 H HE1    . PHE A 1 375 ? 118.204 119.483 124.316 1.00 64.83  ? 366 PHE A HE1    1 
ATOM   4199 H HE2    . PHE A 1 375 ? 116.927 117.557 127.577 1.00 64.83  ? 366 PHE A HE2    1 
ATOM   4200 H HZ     . PHE A 1 375 ? 116.938 117.811 125.282 1.00 64.83  ? 366 PHE A HZ     1 
ATOM   4201 N N      . PHE A 1 376 ? 122.292 122.381 129.584 1.00 66.65  ? 367 PHE A N      1 
ATOM   4202 C CA     . PHE A 1 376 ? 122.863 123.490 130.338 1.00 66.65  ? 367 PHE A CA     1 
ATOM   4203 C C      . PHE A 1 376 ? 123.913 124.225 129.514 1.00 66.65  ? 367 PHE A C      1 
ATOM   4204 O O      . PHE A 1 376 ? 123.883 125.458 129.395 1.00 66.65  ? 367 PHE A O      1 
ATOM   4205 C CB     . PHE A 1 376 ? 123.463 122.971 131.643 1.00 66.65  ? 367 PHE A CB     1 
ATOM   4206 C CG     . PHE A 1 376 ? 123.989 124.051 132.538 1.00 66.65  ? 367 PHE A CG     1 
ATOM   4207 C CD1    . PHE A 1 376 ? 123.135 124.764 133.362 1.00 66.65  ? 367 PHE A CD1    1 
ATOM   4208 C CD2    . PHE A 1 376 ? 125.338 124.352 132.561 1.00 66.65  ? 367 PHE A CD2    1 
ATOM   4209 C CE1    . PHE A 1 376 ? 123.615 125.760 134.189 1.00 66.65  ? 367 PHE A CE1    1 
ATOM   4210 C CE2    . PHE A 1 376 ? 125.824 125.347 133.386 1.00 66.65  ? 367 PHE A CE2    1 
ATOM   4211 C CZ     . PHE A 1 376 ? 124.961 126.052 134.201 1.00 66.65  ? 367 PHE A CZ     1 
ATOM   4212 H H      . PHE A 1 376 ? 122.390 121.607 129.947 1.00 66.65  ? 367 PHE A H      1 
ATOM   4213 H HA     . PHE A 1 376 ? 122.159 124.120 130.561 1.00 66.65  ? 367 PHE A HA     1 
ATOM   4214 H HB2    . PHE A 1 376 ? 122.778 122.489 132.132 1.00 66.65  ? 367 PHE A HB2    1 
ATOM   4215 H HB3    . PHE A 1 376 ? 124.199 122.375 131.434 1.00 66.65  ? 367 PHE A HB3    1 
ATOM   4216 H HD1    . PHE A 1 376 ? 122.225 124.571 133.357 1.00 66.65  ? 367 PHE A HD1    1 
ATOM   4217 H HD2    . PHE A 1 376 ? 125.923 123.881 132.013 1.00 66.65  ? 367 PHE A HD2    1 
ATOM   4218 H HE1    . PHE A 1 376 ? 123.031 126.233 134.737 1.00 66.65  ? 367 PHE A HE1    1 
ATOM   4219 H HE2    . PHE A 1 376 ? 126.733 125.543 133.392 1.00 66.65  ? 367 PHE A HE2    1 
ATOM   4220 H HZ     . PHE A 1 376 ? 125.288 126.722 134.757 1.00 66.65  ? 367 PHE A HZ     1 
ATOM   4221 N N      . PHE A 1 377 ? 124.845 123.477 128.919 1.00 67.14  ? 368 PHE A N      1 
ATOM   4222 C CA     . PHE A 1 377 ? 125.922 124.114 128.169 1.00 67.14  ? 368 PHE A CA     1 
ATOM   4223 C C      . PHE A 1 377 ? 125.397 124.826 126.930 1.00 67.14  ? 368 PHE A C      1 
ATOM   4224 O O      . PHE A 1 377 ? 125.826 125.946 126.628 1.00 67.14  ? 368 PHE A O      1 
ATOM   4225 C CB     . PHE A 1 377 ? 126.980 123.083 127.782 1.00 67.14  ? 368 PHE A CB     1 
ATOM   4226 C CG     . PHE A 1 377 ? 128.029 122.866 128.834 1.00 67.14  ? 368 PHE A CG     1 
ATOM   4227 C CD1    . PHE A 1 377 ? 128.689 123.937 129.409 1.00 67.14  ? 368 PHE A CD1    1 
ATOM   4228 C CD2    . PHE A 1 377 ? 128.352 121.589 129.251 1.00 67.14  ? 368 PHE A CD2    1 
ATOM   4229 C CE1    . PHE A 1 377 ? 129.646 123.737 130.374 1.00 67.14  ? 368 PHE A CE1    1 
ATOM   4230 C CE2    . PHE A 1 377 ? 129.311 121.384 130.218 1.00 67.14  ? 368 PHE A CE2    1 
ATOM   4231 C CZ     . PHE A 1 377 ? 129.958 122.459 130.780 1.00 67.14  ? 368 PHE A CZ     1 
ATOM   4232 H H      . PHE A 1 377 ? 124.874 122.618 128.935 1.00 67.14  ? 368 PHE A H      1 
ATOM   4233 H HA     . PHE A 1 377 ? 126.331 124.787 128.732 1.00 67.14  ? 368 PHE A HA     1 
ATOM   4234 H HB2    . PHE A 1 377 ? 126.544 122.233 127.617 1.00 67.14  ? 368 PHE A HB2    1 
ATOM   4235 H HB3    . PHE A 1 377 ? 127.428 123.385 126.976 1.00 67.14  ? 368 PHE A HB3    1 
ATOM   4236 H HD1    . PHE A 1 377 ? 128.482 124.803 129.140 1.00 67.14  ? 368 PHE A HD1    1 
ATOM   4237 H HD2    . PHE A 1 377 ? 127.917 120.859 128.875 1.00 67.14  ? 368 PHE A HD2    1 
ATOM   4238 H HE1    . PHE A 1 377 ? 130.083 124.465 130.753 1.00 67.14  ? 368 PHE A HE1    1 
ATOM   4239 H HE2    . PHE A 1 377 ? 129.520 120.520 130.490 1.00 67.14  ? 368 PHE A HE2    1 
ATOM   4240 H HZ     . PHE A 1 377 ? 130.607 122.323 131.432 1.00 67.14  ? 368 PHE A HZ     1 
ATOM   4241 N N      . ILE A 1 378 ? 124.479 124.200 126.191 1.00 66.23  ? 369 ILE A N      1 
ATOM   4242 C CA     . ILE A 1 378 ? 123.981 124.836 124.977 1.00 66.23  ? 369 ILE A CA     1 
ATOM   4243 C C      . ILE A 1 378 ? 123.199 126.097 125.322 1.00 66.23  ? 369 ILE A C      1 
ATOM   4244 O O      . ILE A 1 378 ? 123.304 127.115 124.629 1.00 66.23  ? 369 ILE A O      1 
ATOM   4245 C CB     . ILE A 1 378 ? 123.143 123.842 124.152 1.00 66.23  ? 369 ILE A CB     1 
ATOM   4246 C CG1    . ILE A 1 378 ? 122.955 124.364 122.729 1.00 66.23  ? 369 ILE A CG1    1 
ATOM   4247 C CG2    . ILE A 1 378 ? 121.793 123.608 124.790 1.00 66.23  ? 369 ILE A CG2    1 
ATOM   4248 C CD1    . ILE A 1 378 ? 122.232 123.399 121.823 1.00 66.23  ? 369 ILE A CD1    1 
ATOM   4249 H H      . ILE A 1 378 ? 124.140 123.429 126.366 1.00 66.23  ? 369 ILE A H      1 
ATOM   4250 H HA     . ILE A 1 378 ? 124.740 125.103 124.435 1.00 66.23  ? 369 ILE A HA     1 
ATOM   4251 H HB     . ILE A 1 378 ? 123.616 122.997 124.113 1.00 66.23  ? 369 ILE A HB     1 
ATOM   4252 H HG12   . ILE A 1 378 ? 122.440 125.185 122.761 1.00 66.23  ? 369 ILE A HG12   1 
ATOM   4253 H HG13   . ILE A 1 378 ? 123.827 124.537 122.343 1.00 66.23  ? 369 ILE A HG13   1 
ATOM   4254 H HG21   . ILE A 1 378 ? 121.923 123.444 125.734 1.00 66.23  ? 369 ILE A HG21   1 
ATOM   4255 H HG22   . ILE A 1 378 ? 121.378 122.835 124.376 1.00 66.23  ? 369 ILE A HG22   1 
ATOM   4256 H HG23   . ILE A 1 378 ? 121.237 124.391 124.661 1.00 66.23  ? 369 ILE A HG23   1 
ATOM   4257 H HD11   . ILE A 1 378 ? 122.659 122.530 121.884 1.00 66.23  ? 369 ILE A HD11   1 
ATOM   4258 H HD12   . ILE A 1 378 ? 122.278 123.726 120.911 1.00 66.23  ? 369 ILE A HD12   1 
ATOM   4259 H HD13   . ILE A 1 378 ? 121.306 123.332 122.104 1.00 66.23  ? 369 ILE A HD13   1 
ATOM   4260 N N      . GLY A 1 379 ? 122.414 126.062 126.401 1.00 64.74  ? 370 GLY A N      1 
ATOM   4261 C CA     . GLY A 1 379 ? 121.708 127.259 126.819 1.00 64.74  ? 370 GLY A CA     1 
ATOM   4262 C C      . GLY A 1 379 ? 122.652 128.376 127.214 1.00 64.74  ? 370 GLY A C      1 
ATOM   4263 O O      . GLY A 1 379 ? 122.446 129.536 126.847 1.00 64.74  ? 370 GLY A O      1 
ATOM   4264 H H      . GLY A 1 379 ? 122.281 125.372 126.896 1.00 64.74  ? 370 GLY A H      1 
ATOM   4265 H HA2    . GLY A 1 379 ? 121.141 127.570 126.096 1.00 64.74  ? 370 GLY A HA2    1 
ATOM   4266 H HA3    . GLY A 1 379 ? 121.146 127.050 127.582 1.00 64.74  ? 370 GLY A HA3    1 
ATOM   4267 N N      . LEU A 1 380 ? 123.709 128.044 127.956 1.00 67.21  ? 371 LEU A N      1 
ATOM   4268 C CA     . LEU A 1 380 ? 124.670 129.073 128.339 1.00 67.21  ? 371 LEU A CA     1 
ATOM   4269 C C      . LEU A 1 380 ? 125.352 129.668 127.111 1.00 67.21  ? 371 LEU A C      1 
ATOM   4270 O O      . LEU A 1 380 ? 125.490 130.894 126.996 1.00 67.21  ? 371 LEU A O      1 
ATOM   4271 C CB     . LEU A 1 380 ? 125.699 128.489 129.307 1.00 67.21  ? 371 LEU A CB     1 
ATOM   4272 C CG     . LEU A 1 380 ? 126.576 129.492 130.060 1.00 67.21  ? 371 LEU A CG     1 
ATOM   4273 C CD1    . LEU A 1 380 ? 125.734 130.414 130.930 1.00 67.21  ? 371 LEU A CD1    1 
ATOM   4274 C CD2    . LEU A 1 380 ? 127.602 128.755 130.901 1.00 67.21  ? 371 LEU A CD2    1 
ATOM   4275 H H      . LEU A 1 380 ? 123.889 127.253 128.242 1.00 67.21  ? 371 LEU A H      1 
ATOM   4276 H HA     . LEU A 1 380 ? 124.195 129.785 128.794 1.00 67.21  ? 371 LEU A HA     1 
ATOM   4277 H HB2    . LEU A 1 380 ? 125.223 127.965 129.972 1.00 67.21  ? 371 LEU A HB2    1 
ATOM   4278 H HB3    . LEU A 1 380 ? 126.293 127.907 128.808 1.00 67.21  ? 371 LEU A HB3    1 
ATOM   4279 H HG     . LEU A 1 380 ? 127.053 130.040 129.417 1.00 67.21  ? 371 LEU A HG     1 
ATOM   4280 H HD11   . LEU A 1 380 ? 126.316 130.885 131.548 1.00 67.21  ? 371 LEU A HD11   1 
ATOM   4281 H HD12   . LEU A 1 380 ? 125.090 129.883 131.425 1.00 67.21  ? 371 LEU A HD12   1 
ATOM   4282 H HD13   . LEU A 1 380 ? 125.269 131.050 130.364 1.00 67.21  ? 371 LEU A HD13   1 
ATOM   4283 H HD21   . LEU A 1 380 ? 128.168 129.401 131.351 1.00 67.21  ? 371 LEU A HD21   1 
ATOM   4284 H HD22   . LEU A 1 380 ? 127.136 128.210 131.554 1.00 67.21  ? 371 LEU A HD22   1 
ATOM   4285 H HD23   . LEU A 1 380 ? 128.137 128.190 130.322 1.00 67.21  ? 371 LEU A HD23   1 
ATOM   4286 N N      . MET A 1 381 ? 125.767 128.820 126.167 1.00 67.11  ? 372 MET A N      1 
ATOM   4287 C CA     . MET A 1 381 ? 126.427 129.329 124.970 1.00 67.11  ? 372 MET A CA     1 
ATOM   4288 C C      . MET A 1 381 ? 125.491 130.220 124.164 1.00 67.11  ? 372 MET A C      1 
ATOM   4289 O O      . MET A 1 381 ? 125.902 131.278 123.674 1.00 67.11  ? 372 MET A O      1 
ATOM   4290 C CB     . MET A 1 381 ? 126.937 128.172 124.114 1.00 67.11  ? 372 MET A CB     1 
ATOM   4291 C CG     . MET A 1 381 ? 128.070 127.372 124.736 1.00 67.11  ? 372 MET A CG     1 
ATOM   4292 S SD     . MET A 1 381 ? 129.457 128.372 125.312 1.00 67.11  ? 372 MET A SD     1 
ATOM   4293 C CE     . MET A 1 381 ? 129.010 128.621 127.029 1.00 67.11  ? 372 MET A CE     1 
ATOM   4294 H H      . MET A 1 381 ? 125.676 127.966 126.196 1.00 67.11  ? 372 MET A H      1 
ATOM   4295 H HA     . MET A 1 381 ? 127.190 129.860 125.242 1.00 67.11  ? 372 MET A HA     1 
ATOM   4296 H HB2    . MET A 1 381 ? 126.201 127.561 123.958 1.00 67.11  ? 372 MET A HB2    1 
ATOM   4297 H HB3    . MET A 1 381 ? 127.255 128.531 123.271 1.00 67.11  ? 372 MET A HB3    1 
ATOM   4298 H HG2    . MET A 1 381 ? 127.726 126.879 125.496 1.00 67.11  ? 372 MET A HG2    1 
ATOM   4299 H HG3    . MET A 1 381 ? 128.408 126.755 124.069 1.00 67.11  ? 372 MET A HG3    1 
ATOM   4300 H HE1    . MET A 1 381 ? 128.260 129.233 127.079 1.00 67.11  ? 372 MET A HE1    1 
ATOM   4301 H HE2    . MET A 1 381 ? 129.771 128.992 127.502 1.00 67.11  ? 372 MET A HE2    1 
ATOM   4302 H HE3    . MET A 1 381 ? 128.766 127.766 127.417 1.00 67.11  ? 372 MET A HE3    1 
ATOM   4303 N N      . SER A 1 382 ? 124.225 129.817 124.018 1.00 63.75  ? 373 SER A N      1 
ATOM   4304 C CA     . SER A 1 382 ? 123.255 130.704 123.389 1.00 63.75  ? 373 SER A CA     1 
ATOM   4305 C C      . SER A 1 382 ? 123.174 132.029 124.130 1.00 63.75  ? 373 SER A C      1 
ATOM   4306 O O      . SER A 1 382 ? 123.111 133.090 123.501 1.00 63.75  ? 373 SER A O      1 
ATOM   4307 C CB     . SER A 1 382 ? 121.882 130.043 123.343 1.00 63.75  ? 373 SER A CB     1 
ATOM   4308 O OG     . SER A 1 382 ? 121.387 129.825 124.649 1.00 63.75  ? 373 SER A OG     1 
ATOM   4309 H H      . SER A 1 382 ? 123.914 129.055 124.268 1.00 63.75  ? 373 SER A H      1 
ATOM   4310 H HA     . SER A 1 382 ? 123.534 130.883 122.477 1.00 63.75  ? 373 SER A HA     1 
ATOM   4311 H HB2    . SER A 1 382 ? 121.267 130.620 122.864 1.00 63.75  ? 373 SER A HB2    1 
ATOM   4312 H HB3    . SER A 1 382 ? 121.959 129.190 122.890 1.00 63.75  ? 373 SER A HB3    1 
ATOM   4313 H HG     . SER A 1 382 ? 121.888 129.291 125.058 1.00 63.75  ? 373 SER A HG     1 
ATOM   4314 N N      . MET A 1 383 ? 123.199 131.991 125.462 1.00 63.63  ? 374 MET A N      1 
ATOM   4315 C CA     . MET A 1 383 ? 123.232 133.219 126.245 1.00 63.63  ? 374 MET A CA     1 
ATOM   4316 C C      . MET A 1 383 ? 124.511 134.013 126.038 1.00 63.63  ? 374 MET A C      1 
ATOM   4317 O O      . MET A 1 383 ? 124.555 135.187 126.420 1.00 63.63  ? 374 MET A O      1 
ATOM   4318 C CB     . MET A 1 383 ? 123.078 132.908 127.734 1.00 63.63  ? 374 MET A CB     1 
ATOM   4319 C CG     . MET A 1 383 ? 121.680 132.495 128.157 1.00 63.63  ? 374 MET A CG     1 
ATOM   4320 S SD     . MET A 1 383 ? 121.515 132.442 129.951 1.00 63.63  ? 374 MET A SD     1 
ATOM   4321 C CE     . MET A 1 383 ? 119.817 131.911 130.122 1.00 63.63  ? 374 MET A CE     1 
ATOM   4322 H H      . MET A 1 383 ? 123.196 131.269 125.931 1.00 63.63  ? 374 MET A H      1 
ATOM   4323 H HA     . MET A 1 383 ? 122.480 133.773 125.979 1.00 63.63  ? 374 MET A HA     1 
ATOM   4324 H HB2    . MET A 1 383 ? 123.680 132.185 127.967 1.00 63.63  ? 374 MET A HB2    1 
ATOM   4325 H HB3    . MET A 1 383 ? 123.316 133.700 128.238 1.00 63.63  ? 374 MET A HB3    1 
ATOM   4326 H HG2    . MET A 1 383 ? 121.035 133.133 127.811 1.00 63.63  ? 374 MET A HG2    1 
ATOM   4327 H HG3    . MET A 1 383 ? 121.491 131.609 127.811 1.00 63.63  ? 374 MET A HG3    1 
ATOM   4328 H HE1    . MET A 1 383 ? 119.580 131.909 131.062 1.00 63.63  ? 374 MET A HE1    1 
ATOM   4329 H HE2    . MET A 1 383 ? 119.245 132.526 129.636 1.00 63.63  ? 374 MET A HE2    1 
ATOM   4330 H HE3    . MET A 1 383 ? 119.729 131.017 129.756 1.00 63.63  ? 374 MET A HE3    1 
ATOM   4331 N N      . MET A 1 384 ? 125.551 133.410 125.462 1.00 65.27  ? 375 MET A N      1 
ATOM   4332 C CA     . MET A 1 384 ? 126.798 134.120 125.211 1.00 65.27  ? 375 MET A CA     1 
ATOM   4333 C C      . MET A 1 384 ? 126.856 134.834 123.865 1.00 65.27  ? 375 MET A C      1 
ATOM   4334 O O      . MET A 1 384 ? 127.648 135.769 123.722 1.00 65.27  ? 375 MET A O      1 
ATOM   4335 C CB     . MET A 1 384 ? 127.987 133.153 125.290 1.00 65.27  ? 375 MET A CB     1 
ATOM   4336 C CG     . MET A 1 384 ? 128.378 132.764 126.697 1.00 65.27  ? 375 MET A CG     1 
ATOM   4337 S SD     . MET A 1 384 ? 129.923 131.839 126.727 1.00 65.27  ? 375 MET A SD     1 
ATOM   4338 C CE     . MET A 1 384 ? 130.169 131.630 128.487 1.00 65.27  ? 375 MET A CE     1 
ATOM   4339 H H      . MET A 1 384 ? 125.554 132.589 125.207 1.00 65.27  ? 375 MET A H      1 
ATOM   4340 H HA     . MET A 1 384 ? 126.920 134.781 125.910 1.00 65.27  ? 375 MET A HA     1 
ATOM   4341 H HB2    . MET A 1 384 ? 127.762 132.338 124.816 1.00 65.27  ? 375 MET A HB2    1 
ATOM   4342 H HB3    . MET A 1 384 ? 128.757 133.571 124.874 1.00 65.27  ? 375 MET A HB3    1 
ATOM   4343 H HG2    . MET A 1 384 ? 128.494 133.565 127.232 1.00 65.27  ? 375 MET A HG2    1 
ATOM   4344 H HG3    . MET A 1 384 ? 127.681 132.206 127.078 1.00 65.27  ? 375 MET A HG3    1 
ATOM   4345 H HE1    . MET A 1 384 ? 130.235 132.503 128.905 1.00 65.27  ? 375 MET A HE1    1 
ATOM   4346 H HE2    . MET A 1 384 ? 130.988 131.131 128.631 1.00 65.27  ? 375 MET A HE2    1 
ATOM   4347 H HE3    . MET A 1 384 ? 129.415 131.143 128.854 1.00 65.27  ? 375 MET A HE3    1 
ATOM   4348 N N      . ILE A 1 385 ? 126.043 134.430 122.884 1.00 64.26  ? 376 ILE A N      1 
ATOM   4349 C CA     . ILE A 1 385 ? 126.219 134.935 121.519 1.00 64.26  ? 376 ILE A CA     1 
ATOM   4350 C C      . ILE A 1 385 ? 126.075 136.450 121.427 1.00 64.26  ? 376 ILE A C      1 
ATOM   4351 O O      . ILE A 1 385 ? 126.948 137.096 120.825 1.00 64.26  ? 376 ILE A O      1 
ATOM   4352 C CB     . ILE A 1 385 ? 125.261 134.205 120.561 1.00 64.26  ? 376 ILE A CB     1 
ATOM   4353 C CG1    . ILE A 1 385 ? 125.796 132.804 120.252 1.00 64.26  ? 376 ILE A CG1    1 
ATOM   4354 C CG2    . ILE A 1 385 ? 125.062 135.019 119.285 1.00 64.26  ? 376 ILE A CG2    1 
ATOM   4355 C CD1    . ILE A 1 385 ? 124.905 131.982 119.345 1.00 64.26  ? 376 ILE A CD1    1 
ATOM   4356 H H      . ILE A 1 385 ? 125.394 133.873 122.982 1.00 64.26  ? 376 ILE A H      1 
ATOM   4357 H HA     . ILE A 1 385 ? 127.121 134.721 121.236 1.00 64.26  ? 376 ILE A HA     1 
ATOM   4358 H HB     . ILE A 1 385 ? 124.401 134.113 121.001 1.00 64.26  ? 376 ILE A HB     1 
ATOM   4359 H HG12   . ILE A 1 385 ? 126.660 132.889 119.818 1.00 64.26  ? 376 ILE A HG12   1 
ATOM   4360 H HG13   . ILE A 1 385 ? 125.896 132.319 121.087 1.00 64.26  ? 376 ILE A HG13   1 
ATOM   4361 H HG21   . ILE A 1 385 ? 124.496 135.784 119.475 1.00 64.26  ? 376 ILE A HG21   1 
ATOM   4362 H HG22   . ILE A 1 385 ? 124.631 134.468 118.614 1.00 64.26  ? 376 ILE A HG22   1 
ATOM   4363 H HG23   . ILE A 1 385 ? 125.927 135.314 118.961 1.00 64.26  ? 376 ILE A HG23   1 
ATOM   4364 H HD11   . ILE A 1 385 ? 125.149 131.046 119.425 1.00 64.26  ? 376 ILE A HD11   1 
ATOM   4365 H HD12   . ILE A 1 385 ? 123.982 132.108 119.616 1.00 64.26  ? 376 ILE A HD12   1 
ATOM   4366 H HD13   . ILE A 1 385 ? 125.025 132.278 118.430 1.00 64.26  ? 376 ILE A HD13   1 
ATOM   4367 N N      . PRO A 1 386 ? 125.036 137.074 121.971 1.00 64.02  ? 377 PRO A N      1 
ATOM   4368 C CA     . PRO A 1 386 ? 124.790 138.486 121.648 1.00 64.02  ? 377 PRO A CA     1 
ATOM   4369 C C      . PRO A 1 386 ? 125.713 139.466 122.356 1.00 64.02  ? 377 PRO A C      1 
ATOM   4370 O O      . PRO A 1 386 ? 125.423 140.666 122.385 1.00 64.02  ? 377 PRO A O      1 
ATOM   4371 C CB     . PRO A 1 386 ? 123.334 138.687 122.080 1.00 64.02  ? 377 PRO A CB     1 
ATOM   4372 C CG     . PRO A 1 386 ? 123.139 137.717 123.173 1.00 64.02  ? 377 PRO A CG     1 
ATOM   4373 C CD     . PRO A 1 386 ? 123.977 136.517 122.829 1.00 64.02  ? 377 PRO A CD     1 
ATOM   4374 H HA     . PRO A 1 386 ? 124.859 138.626 120.690 1.00 64.02  ? 377 PRO A HA     1 
ATOM   4375 H HB2    . PRO A 1 386 ? 123.206 139.595 122.397 1.00 64.02  ? 377 PRO A HB2    1 
ATOM   4376 H HB3    . PRO A 1 386 ? 122.742 138.493 121.338 1.00 64.02  ? 377 PRO A HB3    1 
ATOM   4377 H HG2    . PRO A 1 386 ? 123.435 138.113 124.008 1.00 64.02  ? 377 PRO A HG2    1 
ATOM   4378 H HG3    . PRO A 1 386 ? 122.202 137.472 123.226 1.00 64.02  ? 377 PRO A HG3    1 
ATOM   4379 H HD2    . PRO A 1 386 ? 124.356 136.135 123.635 1.00 64.02  ? 377 PRO A HD2    1 
ATOM   4380 H HD3    . PRO A 1 386 ? 123.450 135.866 122.341 1.00 64.02  ? 377 PRO A HD3    1 
ATOM   4381 N N      . LEU A 1 387 ? 126.815 138.988 122.929 1.00 66.60  ? 378 LEU A N      1 
ATOM   4382 C CA     . LEU A 1 387 ? 127.752 139.856 123.633 1.00 66.60  ? 378 LEU A CA     1 
ATOM   4383 C C      . LEU A 1 387 ? 129.134 139.877 122.999 1.00 66.60  ? 378 LEU A C      1 
ATOM   4384 O O      . LEU A 1 387 ? 129.713 140.957 122.831 1.00 66.60  ? 378 LEU A O      1 
ATOM   4385 C CB     . LEU A 1 387 ? 127.863 139.423 125.103 1.00 66.60  ? 378 LEU A CB     1 
ATOM   4386 C CG     . LEU A 1 387 ? 126.636 139.709 125.970 1.00 66.60  ? 378 LEU A CG     1 
ATOM   4387 C CD1    . LEU A 1 387 ? 126.809 139.103 127.353 1.00 66.60  ? 378 LEU A CD1    1 
ATOM   4388 C CD2    . LEU A 1 387 ? 126.384 141.204 126.072 1.00 66.60  ? 378 LEU A CD2    1 
ATOM   4389 H H      . LEU A 1 387 ? 127.045 138.160 122.927 1.00 66.60  ? 378 LEU A H      1 
ATOM   4390 H HA     . LEU A 1 387 ? 127.415 140.764 123.617 1.00 66.60  ? 378 LEU A HA     1 
ATOM   4391 H HB2    . LEU A 1 387 ? 128.020 138.466 125.129 1.00 66.60  ? 378 LEU A HB2    1 
ATOM   4392 H HB3    . LEU A 1 387 ? 128.615 139.886 125.503 1.00 66.60  ? 378 LEU A HB3    1 
ATOM   4393 H HG     . LEU A 1 387 ? 125.858 139.301 125.560 1.00 66.60  ? 378 LEU A HG     1 
ATOM   4394 H HD11   . LEU A 1 387 ? 126.930 138.145 127.265 1.00 66.60  ? 378 LEU A HD11   1 
ATOM   4395 H HD12   . LEU A 1 387 ? 126.016 139.291 127.879 1.00 66.60  ? 378 LEU A HD12   1 
ATOM   4396 H HD13   . LEU A 1 387 ? 127.588 139.497 127.776 1.00 66.60  ? 378 LEU A HD13   1 
ATOM   4397 H HD21   . LEU A 1 387 ? 125.716 141.364 126.757 1.00 66.60  ? 378 LEU A HD21   1 
ATOM   4398 H HD22   . LEU A 1 387 ? 127.213 141.649 126.310 1.00 66.60  ? 378 LEU A HD22   1 
ATOM   4399 H HD23   . LEU A 1 387 ? 126.066 141.532 125.217 1.00 66.60  ? 378 LEU A HD23   1 
ATOM   4400 N N      . CYS A 1 388 ? 129.683 138.718 122.641 1.00 66.53  ? 379 CYS A N      1 
ATOM   4401 C CA     . CYS A 1 388 ? 131.055 138.662 122.153 1.00 66.53  ? 379 CYS A CA     1 
ATOM   4402 C C      . CYS A 1 388 ? 131.231 139.555 120.933 1.00 66.53  ? 379 CYS A C      1 
ATOM   4403 O O      . CYS A 1 388 ? 130.403 139.552 120.020 1.00 66.53  ? 379 CYS A O      1 
ATOM   4404 C CB     . CYS A 1 388 ? 131.432 137.221 121.817 1.00 66.53  ? 379 CYS A CB     1 
ATOM   4405 S SG     . CYS A 1 388 ? 131.602 136.157 123.265 1.00 66.53  ? 379 CYS A SG     1 
ATOM   4406 H H      . CYS A 1 388 ? 129.285 137.957 122.673 1.00 66.53  ? 379 CYS A H      1 
ATOM   4407 H HA     . CYS A 1 388 ? 131.654 138.977 122.848 1.00 66.53  ? 379 CYS A HA     1 
ATOM   4408 H HB2    . CYS A 1 388 ? 130.741 136.843 121.251 1.00 66.53  ? 379 CYS A HB2    1 
ATOM   4409 H HB3    . CYS A 1 388 ? 132.279 137.223 121.346 1.00 66.53  ? 379 CYS A HB3    1 
ATOM   4410 H HG     . CYS A 1 388 ? 130.555 136.121 123.849 1.00 66.53  ? 379 CYS A HG     1 
ATOM   4411 N N      . SER A 1 389 ? 132.320 140.323 120.926 1.00 69.06  ? 380 SER A N      1 
ATOM   4412 C CA     . SER A 1 389 ? 132.623 141.267 119.858 1.00 69.06  ? 380 SER A CA     1 
ATOM   4413 C C      . SER A 1 389 ? 133.770 140.807 118.971 1.00 69.06  ? 380 SER A C      1 
ATOM   4414 O O      . SER A 1 389 ? 133.654 140.848 117.743 1.00 69.06  ? 380 SER A O      1 
ATOM   4415 C CB     . SER A 1 389 ? 132.950 142.641 120.457 1.00 69.06  ? 380 SER A CB     1 
ATOM   4416 O OG     . SER A 1 389 ? 134.048 142.557 121.347 1.00 69.06  ? 380 SER A OG     1 
ATOM   4417 H H      . SER A 1 389 ? 132.913 140.312 121.548 1.00 69.06  ? 380 SER A H      1 
ATOM   4418 H HA     . SER A 1 389 ? 131.838 141.370 119.297 1.00 69.06  ? 380 SER A HA     1 
ATOM   4419 H HB2    . SER A 1 389 ? 133.172 143.255 119.739 1.00 69.06  ? 380 SER A HB2    1 
ATOM   4420 H HB3    . SER A 1 389 ? 132.175 142.966 120.942 1.00 69.06  ? 380 SER A HB3    1 
ATOM   4421 H HG     . SER A 1 389 ? 134.220 143.316 121.664 1.00 69.06  ? 380 SER A HG     1 
ATOM   4422 N N      . ILE A 1 390 ? 134.887 140.376 119.559 1.00 67.41  ? 381 ILE A N      1 
ATOM   4423 C CA     . ILE A 1 390 ? 135.993 139.865 118.759 1.00 67.41  ? 381 ILE A CA     1 
ATOM   4424 C C      . ILE A 1 390 ? 135.528 138.629 118.007 1.00 67.41  ? 381 ILE A C      1 
ATOM   4425 O O      . ILE A 1 390 ? 134.864 137.750 118.570 1.00 67.41  ? 381 ILE A O      1 
ATOM   4426 C CB     . ILE A 1 390 ? 137.207 139.559 119.649 1.00 67.41  ? 381 ILE A CB     1 
ATOM   4427 C CG1    . ILE A 1 390 ? 137.659 140.816 120.401 1.00 67.41  ? 381 ILE A CG1    1 
ATOM   4428 C CG2    . ILE A 1 390 ? 138.346 138.997 118.814 1.00 67.41  ? 381 ILE A CG2    1 
ATOM   4429 C CD1    . ILE A 1 390 ? 138.041 141.980 119.506 1.00 67.41  ? 381 ILE A CD1    1 
ATOM   4430 H H      . ILE A 1 390 ? 135.025 140.368 120.408 1.00 67.41  ? 381 ILE A H      1 
ATOM   4431 H HA     . ILE A 1 390 ? 136.251 140.533 118.105 1.00 67.41  ? 381 ILE A HA     1 
ATOM   4432 H HB     . ILE A 1 390 ? 136.946 138.890 120.301 1.00 67.41  ? 381 ILE A HB     1 
ATOM   4433 H HG12   . ILE A 1 390 ? 136.938 141.112 120.978 1.00 67.41  ? 381 ILE A HG12   1 
ATOM   4434 H HG13   . ILE A 1 390 ? 138.435 140.592 120.938 1.00 67.41  ? 381 ILE A HG13   1 
ATOM   4435 H HG21   . ILE A 1 390 ? 138.138 138.083 118.567 1.00 67.41  ? 381 ILE A HG21   1 
ATOM   4436 H HG22   . ILE A 1 390 ? 138.452 139.540 118.018 1.00 67.41  ? 381 ILE A HG22   1 
ATOM   4437 H HG23   . ILE A 1 390 ? 139.161 139.017 119.341 1.00 67.41  ? 381 ILE A HG23   1 
ATOM   4438 H HD11   . ILE A 1 390 ? 138.416 142.686 120.055 1.00 67.41  ? 381 ILE A HD11   1 
ATOM   4439 H HD12   . ILE A 1 390 ? 137.248 142.305 119.051 1.00 67.41  ? 381 ILE A HD12   1 
ATOM   4440 H HD13   . ILE A 1 390 ? 138.698 141.684 118.858 1.00 67.41  ? 381 ILE A HD13   1 
ATOM   4441 N N      . PHE A 1 391 ? 135.882 138.553 116.723 1.00 68.14  ? 382 PHE A N      1 
ATOM   4442 C CA     . PHE A 1 391 ? 135.313 137.526 115.857 1.00 68.14  ? 382 PHE A CA     1 
ATOM   4443 C C      . PHE A 1 391 ? 135.527 136.131 116.433 1.00 68.14  ? 382 PHE A C      1 
ATOM   4444 O O      . PHE A 1 391 ? 134.573 135.364 116.603 1.00 68.14  ? 382 PHE A O      1 
ATOM   4445 C CB     . PHE A 1 391 ? 135.923 137.631 114.458 1.00 68.14  ? 382 PHE A CB     1 
ATOM   4446 C CG     . PHE A 1 391 ? 135.104 136.967 113.389 1.00 68.14  ? 382 PHE A CG     1 
ATOM   4447 C CD1    . PHE A 1 391 ? 135.169 135.600 113.195 1.00 68.14  ? 382 PHE A CD1    1 
ATOM   4448 C CD2    . PHE A 1 391 ? 134.270 137.711 112.577 1.00 68.14  ? 382 PHE A CD2    1 
ATOM   4449 C CE1    . PHE A 1 391 ? 134.416 134.991 112.215 1.00 68.14  ? 382 PHE A CE1    1 
ATOM   4450 C CE2    . PHE A 1 391 ? 133.516 137.105 111.596 1.00 68.14  ? 382 PHE A CE2    1 
ATOM   4451 C CZ     . PHE A 1 391 ? 133.590 135.744 111.416 1.00 68.14  ? 382 PHE A CZ     1 
ATOM   4452 H H      . PHE A 1 391 ? 136.443 139.077 116.336 1.00 68.14  ? 382 PHE A H      1 
ATOM   4453 H HA     . PHE A 1 391 ? 134.357 137.675 115.778 1.00 68.14  ? 382 PHE A HA     1 
ATOM   4454 H HB2    . PHE A 1 391 ? 136.011 138.568 114.224 1.00 68.14  ? 382 PHE A HB2    1 
ATOM   4455 H HB3    . PHE A 1 391 ? 136.798 137.211 114.466 1.00 68.14  ? 382 PHE A HB3    1 
ATOM   4456 H HD1    . PHE A 1 391 ? 135.726 135.085 113.733 1.00 68.14  ? 382 PHE A HD1    1 
ATOM   4457 H HD2    . PHE A 1 391 ? 134.215 138.632 112.696 1.00 68.14  ? 382 PHE A HD2    1 
ATOM   4458 H HE1    . PHE A 1 391 ? 134.468 134.070 112.094 1.00 68.14  ? 382 PHE A HE1    1 
ATOM   4459 H HE2    . PHE A 1 391 ? 132.957 137.616 111.056 1.00 68.14  ? 382 PHE A HE2    1 
ATOM   4460 H HZ     . PHE A 1 391 ? 133.082 135.334 110.754 1.00 68.14  ? 382 PHE A HZ     1 
ATOM   4461 N N      . GLY A 1 392 ? 136.774 135.798 116.773 1.00 68.86  ? 383 GLY A N      1 
ATOM   4462 C CA     . GLY A 1 392 ? 137.088 134.431 117.156 1.00 68.86  ? 383 GLY A CA     1 
ATOM   4463 C C      . GLY A 1 392 ? 136.261 133.928 118.321 1.00 68.86  ? 383 GLY A C      1 
ATOM   4464 O O      . GLY A 1 392 ? 136.029 132.721 118.450 1.00 68.86  ? 383 GLY A O      1 
ATOM   4465 H H      . GLY A 1 392 ? 137.442 136.340 116.789 1.00 68.86  ? 383 GLY A H      1 
ATOM   4466 H HA2    . GLY A 1 392 ? 136.937 133.844 116.399 1.00 68.86  ? 383 GLY A HA2    1 
ATOM   4467 H HA3    . GLY A 1 392 ? 138.025 134.376 117.403 1.00 68.86  ? 383 GLY A HA3    1 
ATOM   4468 N N      . ALA A 1 393 ? 135.809 134.835 119.184 1.00 68.15  ? 384 ALA A N      1 
ATOM   4469 C CA     . ALA A 1 393 ? 134.975 134.419 120.302 1.00 68.15  ? 384 ALA A CA     1 
ATOM   4470 C C      . ALA A 1 393 ? 133.680 133.796 119.807 1.00 68.15  ? 384 ALA A C      1 
ATOM   4471 O O      . ALA A 1 393 ? 133.191 132.817 120.384 1.00 68.15  ? 384 ALA A O      1 
ATOM   4472 C CB     . ALA A 1 393 ? 134.687 135.611 121.213 1.00 68.15  ? 384 ALA A CB     1 
ATOM   4473 H H      . ALA A 1 393 ? 135.967 135.679 119.145 1.00 68.15  ? 384 ALA A H      1 
ATOM   4474 H HA     . ALA A 1 393 ? 135.451 133.752 120.821 1.00 68.15  ? 384 ALA A HA     1 
ATOM   4475 H HB1    . ALA A 1 393 ? 134.113 135.323 121.940 1.00 68.15  ? 384 ALA A HB1    1 
ATOM   4476 H HB2    . ALA A 1 393 ? 135.526 135.945 121.567 1.00 68.15  ? 384 ALA A HB2    1 
ATOM   4477 H HB3    . ALA A 1 393 ? 134.247 136.303 120.696 1.00 68.15  ? 384 ALA A HB3    1 
ATOM   4478 N N      . LEU A 1 394 ? 133.105 134.352 118.740 1.00 67.01  ? 385 LEU A N      1 
ATOM   4479 C CA     . LEU A 1 394 ? 131.871 133.790 118.206 1.00 67.01  ? 385 LEU A CA     1 
ATOM   4480 C C      . LEU A 1 394 ? 132.097 132.376 117.685 1.00 67.01  ? 385 LEU A C      1 
ATOM   4481 O O      . LEU A 1 394 ? 131.259 131.491 117.889 1.00 67.01  ? 385 LEU A O      1 
ATOM   4482 C CB     . LEU A 1 394 ? 131.315 134.699 117.109 1.00 67.01  ? 385 LEU A CB     1 
ATOM   4483 C CG     . LEU A 1 394 ? 129.958 134.314 116.513 1.00 67.01  ? 385 LEU A CG     1 
ATOM   4484 C CD1    . LEU A 1 394 ? 128.924 134.074 117.599 1.00 67.01  ? 385 LEU A CD1    1 
ATOM   4485 C CD2    . LEU A 1 394 ? 129.474 135.392 115.561 1.00 67.01  ? 385 LEU A CD2    1 
ATOM   4486 H H      . LEU A 1 394 ? 133.403 135.038 118.317 1.00 67.01  ? 385 LEU A H      1 
ATOM   4487 H HA     . LEU A 1 394 ? 131.218 133.745 118.922 1.00 67.01  ? 385 LEU A HA     1 
ATOM   4488 H HB2    . LEU A 1 394 ? 131.224 135.593 117.475 1.00 67.01  ? 385 LEU A HB2    1 
ATOM   4489 H HB3    . LEU A 1 394 ? 131.954 134.717 116.379 1.00 67.01  ? 385 LEU A HB3    1 
ATOM   4490 H HG     . LEU A 1 394 ? 130.058 133.492 116.008 1.00 67.01  ? 385 LEU A HG     1 
ATOM   4491 H HD11   . LEU A 1 394 ? 128.050 133.988 117.187 1.00 67.01  ? 385 LEU A HD11   1 
ATOM   4492 H HD12   . LEU A 1 394 ? 129.147 133.257 118.073 1.00 67.01  ? 385 LEU A HD12   1 
ATOM   4493 H HD13   . LEU A 1 394 ? 128.929 134.826 118.212 1.00 67.01  ? 385 LEU A HD13   1 
ATOM   4494 H HD21   . LEU A 1 394 ? 128.792 135.017 114.983 1.00 67.01  ? 385 LEU A HD21   1 
ATOM   4495 H HD22   . LEU A 1 394 ? 129.102 136.123 116.077 1.00 67.01  ? 385 LEU A HD22   1 
ATOM   4496 H HD23   . LEU A 1 394 ? 130.223 135.705 115.029 1.00 67.01  ? 385 LEU A HD23   1 
ATOM   4497 N N      . ILE A 1 395 ? 133.234 132.138 117.028 1.00 69.24  ? 386 ILE A N      1 
ATOM   4498 C CA     . ILE A 1 395 ? 133.537 130.795 116.541 1.00 69.24  ? 386 ILE A CA     1 
ATOM   4499 C C      . ILE A 1 395 ? 133.746 129.837 117.707 1.00 69.24  ? 386 ILE A C      1 
ATOM   4500 O O      . ILE A 1 395 ? 133.330 128.673 117.653 1.00 69.24  ? 386 ILE A O      1 
ATOM   4501 C CB     . ILE A 1 395 ? 134.760 130.829 115.608 1.00 69.24  ? 386 ILE A CB     1 
ATOM   4502 C CG1    . ILE A 1 395 ? 134.346 131.347 114.229 1.00 69.24  ? 386 ILE A CG1    1 
ATOM   4503 C CG2    . ILE A 1 395 ? 135.392 129.447 115.507 1.00 69.24  ? 386 ILE A CG2    1 
ATOM   4504 C CD1    . ILE A 1 395 ? 135.498 131.555 113.268 1.00 69.24  ? 386 ILE A CD1    1 
ATOM   4505 H H      . ILE A 1 395 ? 133.835 132.727 116.854 1.00 69.24  ? 386 ILE A H      1 
ATOM   4506 H HA     . ILE A 1 395 ? 132.781 130.473 116.026 1.00 69.24  ? 386 ILE A HA     1 
ATOM   4507 H HB     . ILE A 1 395 ? 135.415 131.440 115.981 1.00 69.24  ? 386 ILE A HB     1 
ATOM   4508 H HG12   . ILE A 1 395 ? 133.738 130.708 113.826 1.00 69.24  ? 386 ILE A HG12   1 
ATOM   4509 H HG13   . ILE A 1 395 ? 133.897 132.200 114.339 1.00 69.24  ? 386 ILE A HG13   1 
ATOM   4510 H HG21   . ILE A 1 395 ? 135.993 129.423 114.747 1.00 69.24  ? 386 ILE A HG21   1 
ATOM   4511 H HG22   . ILE A 1 395 ? 135.891 129.264 116.318 1.00 69.24  ? 386 ILE A HG22   1 
ATOM   4512 H HG23   . ILE A 1 395 ? 134.691 128.787 115.390 1.00 69.24  ? 386 ILE A HG23   1 
ATOM   4513 H HD11   . ILE A 1 395 ? 136.220 132.006 113.734 1.00 69.24  ? 386 ILE A HD11   1 
ATOM   4514 H HD12   . ILE A 1 395 ? 135.194 132.099 112.524 1.00 69.24  ? 386 ILE A HD12   1 
ATOM   4515 H HD13   . ILE A 1 395 ? 135.801 130.693 112.943 1.00 69.24  ? 386 ILE A HD13   1 
ATOM   4516 N N      . ALA A 1 396 ? 134.410 130.297 118.768 1.00 70.10  ? 387 ALA A N      1 
ATOM   4517 C CA     . ALA A 1 396 ? 134.593 129.448 119.942 1.00 70.10  ? 387 ALA A CA     1 
ATOM   4518 C C      . ALA A 1 396 ? 133.248 129.069 120.551 1.00 70.10  ? 387 ALA A C      1 
ATOM   4519 O O      . ALA A 1 396 ? 133.008 127.904 120.899 1.00 70.10  ? 387 ALA A O      1 
ATOM   4520 C CB     . ALA A 1 396 ? 135.469 130.161 120.971 1.00 70.10  ? 387 ALA A CB     1 
ATOM   4521 H H      . ALA A 1 396 ? 134.758 131.082 118.831 1.00 70.10  ? 387 ALA A H      1 
ATOM   4522 H HA     . ALA A 1 396 ? 135.044 128.632 119.676 1.00 70.10  ? 387 ALA A HA     1 
ATOM   4523 H HB1    . ALA A 1 396 ? 136.332 130.353 120.572 1.00 70.10  ? 387 ALA A HB1    1 
ATOM   4524 H HB2    . ALA A 1 396 ? 135.582 129.584 121.743 1.00 70.10  ? 387 ALA A HB2    1 
ATOM   4525 H HB3    . ALA A 1 396 ? 135.035 130.987 121.236 1.00 70.10  ? 387 ALA A HB3    1 
ATOM   4526 N N      . VAL A 1 397 ? 132.354 130.050 120.682 1.00 68.72  ? 388 VAL A N      1 
ATOM   4527 C CA     . VAL A 1 397 ? 131.017 129.774 121.198 1.00 68.72  ? 388 VAL A CA     1 
ATOM   4528 C C      . VAL A 1 397 ? 130.297 128.787 120.290 1.00 68.72  ? 388 VAL A C      1 
ATOM   4529 O O      . VAL A 1 397 ? 129.596 127.884 120.761 1.00 68.72  ? 388 VAL A O      1 
ATOM   4530 C CB     . VAL A 1 397 ? 130.226 131.087 121.352 1.00 68.72  ? 388 VAL A CB     1 
ATOM   4531 C CG1    . VAL A 1 397 ? 128.800 130.803 121.791 1.00 68.72  ? 388 VAL A CG1    1 
ATOM   4532 C CG2    . VAL A 1 397 ? 130.916 132.010 122.345 1.00 68.72  ? 388 VAL A CG2    1 
ATOM   4533 H H      . VAL A 1 397 ? 132.496 130.874 120.482 1.00 68.72  ? 388 VAL A H      1 
ATOM   4534 H HA     . VAL A 1 397 ? 131.097 129.369 122.075 1.00 68.72  ? 388 VAL A HA     1 
ATOM   4535 H HB     . VAL A 1 397 ? 130.193 131.539 120.495 1.00 68.72  ? 388 VAL A HB     1 
ATOM   4536 H HG11   . VAL A 1 397 ? 128.308 130.421 121.047 1.00 68.72  ? 388 VAL A HG11   1 
ATOM   4537 H HG12   . VAL A 1 397 ? 128.815 130.179 122.533 1.00 68.72  ? 388 VAL A HG12   1 
ATOM   4538 H HG13   . VAL A 1 397 ? 128.383 131.635 122.064 1.00 68.72  ? 388 VAL A HG13   1 
ATOM   4539 H HG21   . VAL A 1 397 ? 131.758 131.614 122.617 1.00 68.72  ? 388 VAL A HG21   1 
ATOM   4540 H HG22   . VAL A 1 397 ? 131.075 132.867 121.920 1.00 68.72  ? 388 VAL A HG22   1 
ATOM   4541 H HG23   . VAL A 1 397 ? 130.342 132.128 123.118 1.00 68.72  ? 388 VAL A HG23   1 
ATOM   4542 N N      . CYS A 1 398 ? 130.456 128.945 118.975 1.00 67.70  ? 389 CYS A N      1 
ATOM   4543 C CA     . CYS A 1 398 ? 129.822 128.026 118.036 1.00 67.70  ? 389 CYS A CA     1 
ATOM   4544 C C      . CYS A 1 398 ? 130.322 126.600 118.230 1.00 67.70  ? 389 CYS A C      1 
ATOM   4545 O O      . CYS A 1 398 ? 129.531 125.651 118.213 1.00 67.70  ? 389 CYS A O      1 
ATOM   4546 C CB     . CYS A 1 398 ? 130.076 128.492 116.605 1.00 67.70  ? 389 CYS A CB     1 
ATOM   4547 S SG     . CYS A 1 398 ? 130.185 127.152 115.398 1.00 67.70  ? 389 CYS A SG     1 
ATOM   4548 H H      . CYS A 1 398 ? 130.921 129.568 118.608 1.00 67.70  ? 389 CYS A H      1 
ATOM   4549 H HA     . CYS A 1 398 ? 128.864 128.031 118.189 1.00 67.70  ? 389 CYS A HA     1 
ATOM   4550 H HB2    . CYS A 1 398 ? 129.350 129.075 116.334 1.00 67.70  ? 389 CYS A HB2    1 
ATOM   4551 H HB3    . CYS A 1 398 ? 130.915 128.979 116.580 1.00 67.70  ? 389 CYS A HB3    1 
ATOM   4552 H HG     . CYS A 1 398 ? 131.130 126.455 115.649 1.00 67.70  ? 389 CYS A HG     1 
ATOM   4553 N N      . LEU A 1 399 ? 131.636 126.426 118.391 1.00 67.55  ? 390 LEU A N      1 
ATOM   4554 C CA     . LEU A 1 399 ? 132.177 125.088 118.615 1.00 67.55  ? 390 LEU A CA     1 
ATOM   4555 C C      . LEU A 1 399 ? 131.622 124.489 119.901 1.00 67.55  ? 390 LEU A C      1 
ATOM   4556 O O      . LEU A 1 399 ? 131.227 123.313 119.941 1.00 67.55  ? 390 LEU A O      1 
ATOM   4557 C CB     . LEU A 1 399 ? 133.705 125.135 118.672 1.00 67.55  ? 390 LEU A CB     1 
ATOM   4558 C CG     . LEU A 1 399 ? 134.464 125.627 117.437 1.00 67.55  ? 390 LEU A CG     1 
ATOM   4559 C CD1    . LEU A 1 399 ? 135.950 125.694 117.738 1.00 67.55  ? 390 LEU A CD1    1 
ATOM   4560 C CD2    . LEU A 1 399 ? 134.216 124.739 116.239 1.00 67.55  ? 390 LEU A CD2    1 
ATOM   4561 H H      . LEU A 1 399 ? 132.223 127.054 118.376 1.00 67.55  ? 390 LEU A H      1 
ATOM   4562 H HA     . LEU A 1 399 ? 131.918 124.512 117.879 1.00 67.55  ? 390 LEU A HA     1 
ATOM   4563 H HB2    . LEU A 1 399 ? 133.957 125.717 119.406 1.00 67.55  ? 390 LEU A HB2    1 
ATOM   4564 H HB3    . LEU A 1 399 ? 134.023 124.238 118.858 1.00 67.55  ? 390 LEU A HB3    1 
ATOM   4565 H HG     . LEU A 1 399 ? 134.162 126.519 117.214 1.00 67.55  ? 390 LEU A HG     1 
ATOM   4566 H HD11   . LEU A 1 399 ? 136.095 126.312 118.472 1.00 67.55  ? 390 LEU A HD11   1 
ATOM   4567 H HD12   . LEU A 1 399 ? 136.418 126.004 116.947 1.00 67.55  ? 390 LEU A HD12   1 
ATOM   4568 H HD13   . LEU A 1 399 ? 136.263 124.810 117.982 1.00 67.55  ? 390 LEU A HD13   1 
ATOM   4569 H HD21   . LEU A 1 399 ? 134.637 125.138 115.461 1.00 67.55  ? 390 LEU A HD21   1 
ATOM   4570 H HD22   . LEU A 1 399 ? 134.603 123.867 116.411 1.00 67.55  ? 390 LEU A HD22   1 
ATOM   4571 H HD23   . LEU A 1 399 ? 133.261 124.659 116.092 1.00 67.55  ? 390 LEU A HD23   1 
ATOM   4572 N N      . ILE A 1 400 ? 131.598 125.287 120.972 1.00 66.86  ? 391 ILE A N      1 
ATOM   4573 C CA     . ILE A 1 400 ? 131.095 124.785 122.246 1.00 66.86  ? 391 ILE A CA     1 
ATOM   4574 C C      . ILE A 1 400 ? 129.638 124.376 122.109 1.00 66.86  ? 391 ILE A C      1 
ATOM   4575 O O      . ILE A 1 400 ? 129.201 123.374 122.685 1.00 66.86  ? 391 ILE A O      1 
ATOM   4576 C CB     . ILE A 1 400 ? 131.286 125.832 123.358 1.00 66.86  ? 391 ILE A CB     1 
ATOM   4577 C CG1    . ILE A 1 400 ? 132.769 126.175 123.519 1.00 66.86  ? 391 ILE A CG1    1 
ATOM   4578 C CG2    . ILE A 1 400 ? 130.740 125.301 124.677 1.00 66.86  ? 391 ILE A CG2    1 
ATOM   4579 C CD1    . ILE A 1 400 ? 133.026 127.384 124.391 1.00 66.86  ? 391 ILE A CD1    1 
ATOM   4580 H H      . ILE A 1 400 ? 131.859 126.106 120.984 1.00 66.86  ? 391 ILE A H      1 
ATOM   4581 H HA     . ILE A 1 400 ? 131.603 123.995 122.493 1.00 66.86  ? 391 ILE A HA     1 
ATOM   4582 H HB     . ILE A 1 400 ? 130.801 126.637 123.119 1.00 66.86  ? 391 ILE A HB     1 
ATOM   4583 H HG12   . ILE A 1 400 ? 133.219 125.419 123.926 1.00 66.86  ? 391 ILE A HG12   1 
ATOM   4584 H HG13   . ILE A 1 400 ? 133.154 126.351 122.648 1.00 66.86  ? 391 ILE A HG13   1 
ATOM   4585 H HG21   . ILE A 1 400 ? 130.922 125.945 125.378 1.00 66.86  ? 391 ILE A HG21   1 
ATOM   4586 H HG22   . ILE A 1 400 ? 129.785 125.160 124.601 1.00 66.86  ? 391 ILE A HG22   1 
ATOM   4587 H HG23   . ILE A 1 400 ? 131.181 124.461 124.881 1.00 66.86  ? 391 ILE A HG23   1 
ATOM   4588 H HD11   . ILE A 1 400 ? 132.461 128.114 124.093 1.00 66.86  ? 391 ILE A HD11   1 
ATOM   4589 H HD12   . ILE A 1 400 ? 133.960 127.636 124.314 1.00 66.86  ? 391 ILE A HD12   1 
ATOM   4590 H HD13   . ILE A 1 400 ? 132.819 127.160 125.312 1.00 66.86  ? 391 ILE A HD13   1 
ATOM   4591 N N      . MET A 1 401 ? 128.859 125.148 121.351 1.00 67.33  ? 392 MET A N      1 
ATOM   4592 C CA     . MET A 1 401 ? 127.477 124.761 121.096 1.00 67.33  ? 392 MET A CA     1 
ATOM   4593 C C      . MET A 1 401 ? 127.417 123.438 120.351 1.00 67.33  ? 392 MET A C      1 
ATOM   4594 O O      . MET A 1 401 ? 126.746 122.497 120.788 1.00 67.33  ? 392 MET A O      1 
ATOM   4595 C CB     . MET A 1 401 ? 126.760 125.844 120.290 1.00 67.33  ? 392 MET A CB     1 
ATOM   4596 C CG     . MET A 1 401 ? 126.400 127.080 121.080 1.00 67.33  ? 392 MET A CG     1 
ATOM   4597 S SD     . MET A 1 401 ? 125.098 128.050 120.299 1.00 67.33  ? 392 MET A SD     1 
ATOM   4598 C CE     . MET A 1 401 ? 125.689 128.125 118.612 1.00 67.33  ? 392 MET A CE     1 
ATOM   4599 H H      . MET A 1 401 ? 129.102 125.885 120.980 1.00 67.33  ? 392 MET A H      1 
ATOM   4600 H HA     . MET A 1 401 ? 127.016 124.665 121.944 1.00 67.33  ? 392 MET A HA     1 
ATOM   4601 H HB2    . MET A 1 401 ? 127.338 126.119 119.561 1.00 67.33  ? 392 MET A HB2    1 
ATOM   4602 H HB3    . MET A 1 401 ? 125.938 125.473 119.935 1.00 67.33  ? 392 MET A HB3    1 
ATOM   4603 H HG2    . MET A 1 401 ? 126.081 126.805 121.952 1.00 67.33  ? 392 MET A HG2    1 
ATOM   4604 H HG3    . MET A 1 401 ? 127.185 127.642 121.171 1.00 67.33  ? 392 MET A HG3    1 
ATOM   4605 H HE1    . MET A 1 401 ? 126.608 128.435 118.613 1.00 67.33  ? 392 MET A HE1    1 
ATOM   4606 H HE2    . MET A 1 401 ? 125.132 128.741 118.111 1.00 67.33  ? 392 MET A HE2    1 
ATOM   4607 H HE3    . MET A 1 401 ? 125.638 127.239 118.219 1.00 67.33  ? 392 MET A HE3    1 
ATOM   4608 N N      . GLY A 1 402 ? 128.144 123.343 119.237 1.00 68.10  ? 393 GLY A N      1 
ATOM   4609 C CA     . GLY A 1 402 ? 127.977 122.213 118.340 1.00 68.10  ? 393 GLY A CA     1 
ATOM   4610 C C      . GLY A 1 402 ? 128.385 120.893 118.961 1.00 68.10  ? 393 GLY A C      1 
ATOM   4611 O O      . GLY A 1 402 ? 127.767 119.859 118.701 1.00 68.10  ? 393 GLY A O      1 
ATOM   4612 H H      . GLY A 1 402 ? 128.733 123.917 118.985 1.00 68.10  ? 393 GLY A H      1 
ATOM   4613 H HA2    . GLY A 1 402 ? 127.047 122.150 118.072 1.00 68.10  ? 393 GLY A HA2    1 
ATOM   4614 H HA3    . GLY A 1 402 ? 128.515 122.353 117.545 1.00 68.10  ? 393 GLY A HA3    1 
ATOM   4615 N N      . LEU A 1 403 ? 129.436 120.903 119.781 1.00 67.74  ? 394 LEU A N      1 
ATOM   4616 C CA     . LEU A 1 403 ? 129.882 119.652 120.387 1.00 67.74  ? 394 LEU A CA     1 
ATOM   4617 C C      . LEU A 1 403 ? 128.757 119.002 121.189 1.00 67.74  ? 394 LEU A C      1 
ATOM   4618 O O      . LEU A 1 403 ? 128.393 117.839 120.958 1.00 67.74  ? 394 LEU A O      1 
ATOM   4619 C CB     . LEU A 1 403 ? 131.102 119.914 121.269 1.00 67.74  ? 394 LEU A CB     1 
ATOM   4620 C CG     . LEU A 1 403 ? 131.804 118.693 121.857 1.00 67.74  ? 394 LEU A CG     1 
ATOM   4621 C CD1    . LEU A 1 403 ? 132.272 117.766 120.759 1.00 67.74  ? 394 LEU A CD1    1 
ATOM   4622 C CD2    . LEU A 1 403 ? 132.974 119.129 122.716 1.00 67.74  ? 394 LEU A CD2    1 
ATOM   4623 H H      . LEU A 1 403 ? 129.893 121.598 119.997 1.00 67.74  ? 394 LEU A H      1 
ATOM   4624 H HA     . LEU A 1 403 ? 130.141 119.038 119.683 1.00 67.74  ? 394 LEU A HA     1 
ATOM   4625 H HB2    . LEU A 1 403 ? 131.759 120.396 120.743 1.00 67.74  ? 394 LEU A HB2    1 
ATOM   4626 H HB3    . LEU A 1 403 ? 130.821 120.468 122.015 1.00 67.74  ? 394 LEU A HB3    1 
ATOM   4627 H HG     . LEU A 1 403 ? 131.181 118.206 122.419 1.00 67.74  ? 394 LEU A HG     1 
ATOM   4628 H HD11   . LEU A 1 403 ? 132.825 117.070 121.148 1.00 67.74  ? 394 LEU A HD11   1 
ATOM   4629 H HD12   . LEU A 1 403 ? 131.498 117.371 120.330 1.00 67.74  ? 394 LEU A HD12   1 
ATOM   4630 H HD13   . LEU A 1 403 ? 132.787 118.276 120.114 1.00 67.74  ? 394 LEU A HD13   1 
ATOM   4631 H HD21   . LEU A 1 403 ? 133.398 118.343 123.095 1.00 67.74  ? 394 LEU A HD21   1 
ATOM   4632 H HD22   . LEU A 1 403 ? 132.647 119.704 123.425 1.00 67.74  ? 394 LEU A HD22   1 
ATOM   4633 H HD23   . LEU A 1 403 ? 133.608 119.613 122.163 1.00 67.74  ? 394 LEU A HD23   1 
ATOM   4634 N N      . PHE A 1 404 ? 128.157 119.757 122.110 1.00 68.33  ? 395 PHE A N      1 
ATOM   4635 C CA     . PHE A 1 404 ? 127.085 119.193 122.922 1.00 68.33  ? 395 PHE A CA     1 
ATOM   4636 C C      . PHE A 1 404 ? 125.796 119.047 122.125 1.00 68.33  ? 395 PHE A C      1 
ATOM   4637 O O      . PHE A 1 404 ? 124.975 118.176 122.434 1.00 68.33  ? 395 PHE A O      1 
ATOM   4638 C CB     . PHE A 1 404 ? 126.864 120.048 124.167 1.00 68.33  ? 395 PHE A CB     1 
ATOM   4639 C CG     . PHE A 1 404 ? 127.916 119.855 125.217 1.00 68.33  ? 395 PHE A CG     1 
ATOM   4640 C CD1    . PHE A 1 404 ? 127.950 118.697 125.969 1.00 68.33  ? 395 PHE A CD1    1 
ATOM   4641 C CD2    . PHE A 1 404 ? 128.873 120.824 125.447 1.00 68.33  ? 395 PHE A CD2    1 
ATOM   4642 C CE1    . PHE A 1 404 ? 128.916 118.509 126.931 1.00 68.33  ? 395 PHE A CE1    1 
ATOM   4643 C CE2    . PHE A 1 404 ? 129.842 120.641 126.410 1.00 68.33  ? 395 PHE A CE2    1 
ATOM   4644 C CZ     . PHE A 1 404 ? 129.863 119.482 127.153 1.00 68.33  ? 395 PHE A CZ     1 
ATOM   4645 H H      . PHE A 1 404 ? 128.347 120.579 122.280 1.00 68.33  ? 395 PHE A H      1 
ATOM   4646 H HA     . PHE A 1 404 ? 127.353 118.308 123.216 1.00 68.33  ? 395 PHE A HA     1 
ATOM   4647 H HB2    . PHE A 1 404 ? 126.870 120.983 123.909 1.00 68.33  ? 395 PHE A HB2    1 
ATOM   4648 H HB3    . PHE A 1 404 ? 126.008 119.821 124.558 1.00 68.33  ? 395 PHE A HB3    1 
ATOM   4649 H HD1    . PHE A 1 404 ? 127.313 118.037 125.823 1.00 68.33  ? 395 PHE A HD1    1 
ATOM   4650 H HD2    . PHE A 1 404 ? 128.863 121.608 124.947 1.00 68.33  ? 395 PHE A HD2    1 
ATOM   4651 H HE1    . PHE A 1 404 ? 128.927 117.725 127.432 1.00 68.33  ? 395 PHE A HE1    1 
ATOM   4652 H HE2    . PHE A 1 404 ? 130.482 121.300 126.559 1.00 68.33  ? 395 PHE A HE2    1 
ATOM   4653 H HZ     . PHE A 1 404 ? 130.516 119.357 127.804 1.00 68.33  ? 395 PHE A HZ     1 
ATOM   4654 N N      . ASP A 1 405 ? 125.605 119.870 121.092 1.00 67.86  ? 396 ASP A N      1 
ATOM   4655 C CA     . ASP A 1 405 ? 124.457 119.684 120.217 1.00 67.86  ? 396 ASP A CA     1 
ATOM   4656 C C      . ASP A 1 405 ? 124.498 118.308 119.575 1.00 67.86  ? 396 ASP A C      1 
ATOM   4657 O O      . ASP A 1 405 ? 123.477 117.617 119.495 1.00 67.86  ? 396 ASP A O      1 
ATOM   4658 C CB     . ASP A 1 405 ? 124.436 120.779 119.153 1.00 67.86  ? 396 ASP A CB     1 
ATOM   4659 C CG     . ASP A 1 405 ? 123.261 120.657 118.210 1.00 67.86  ? 396 ASP A CG     1 
ATOM   4660 O OD1    . ASP A 1 405 ? 122.377 119.812 118.460 1.00 67.86  ? 396 ASP A OD1    1 
ATOM   4661 O OD2    . ASP A 1 405 ? 123.219 121.408 117.214 1.00 67.86  ? 396 ASP A OD2    1 
ATOM   4662 H H      . ASP A 1 405 ? 126.116 120.529 120.883 1.00 67.86  ? 396 ASP A H      1 
ATOM   4663 H HA     . ASP A 1 405 ? 123.642 119.750 120.740 1.00 67.86  ? 396 ASP A HA     1 
ATOM   4664 H HB2    . ASP A 1 405 ? 124.381 121.643 119.591 1.00 67.86  ? 396 ASP A HB2    1 
ATOM   4665 H HB3    . ASP A 1 405 ? 125.249 120.725 118.627 1.00 67.86  ? 396 ASP A HB3    1 
ATOM   4666 N N      . GLY A 1 406 ? 125.675 117.895 119.111 1.00 70.32  ? 397 GLY A N      1 
ATOM   4667 C CA     . GLY A 1 406 ? 125.820 116.547 118.592 1.00 70.32  ? 397 GLY A CA     1 
ATOM   4668 C C      . GLY A 1 406 ? 125.665 115.491 119.669 1.00 70.32  ? 397 GLY A C      1 
ATOM   4669 O O      . GLY A 1 406 ? 125.016 114.462 119.453 1.00 70.32  ? 397 GLY A O      1 
ATOM   4670 H H      . GLY A 1 406 ? 126.391 118.370 119.085 1.00 70.32  ? 397 GLY A H      1 
ATOM   4671 H HA2    . GLY A 1 406 ? 125.150 116.389 117.909 1.00 70.32  ? 397 GLY A HA2    1 
ATOM   4672 H HA3    . GLY A 1 406 ? 126.698 116.449 118.192 1.00 70.32  ? 397 GLY A HA3    1 
ATOM   4673 N N      . CYS A 1 407 ? 126.262 115.725 120.841 1.00 70.89  ? 398 CYS A N      1 
ATOM   4674 C CA     . CYS A 1 407 ? 126.210 114.719 121.899 1.00 70.89  ? 398 CYS A CA     1 
ATOM   4675 C C      . CYS A 1 407 ? 124.770 114.410 122.296 1.00 70.89  ? 398 CYS A C      1 
ATOM   4676 O O      . CYS A 1 407 ? 124.378 113.240 122.410 1.00 70.89  ? 398 CYS A O      1 
ATOM   4677 C CB     . CYS A 1 407 ? 127.002 115.191 123.116 1.00 70.89  ? 398 CYS A CB     1 
ATOM   4678 S SG     . CYS A 1 407 ? 126.018 116.100 124.322 1.00 70.89  ? 398 CYS A SG     1 
ATOM   4679 H H      . CYS A 1 407 ? 126.691 116.442 121.043 1.00 70.89  ? 398 CYS A H      1 
ATOM   4680 H HA     . CYS A 1 407 ? 126.615 113.899 121.576 1.00 70.89  ? 398 CYS A HA     1 
ATOM   4681 H HB2    . CYS A 1 407 ? 127.362 114.416 123.570 1.00 70.89  ? 398 CYS A HB2    1 
ATOM   4682 H HB3    . CYS A 1 407 ? 127.722 115.769 122.820 1.00 70.89  ? 398 CYS A HB3    1 
ATOM   4683 H HG     . CYS A 1 407 ? 126.666 116.218 125.324 1.00 70.89  ? 398 CYS A HG     1 
ATOM   4684 N N      . PHE A 1 408 ? 123.964 115.452 122.514 1.00 67.74  ? 399 PHE A N      1 
ATOM   4685 C CA     . PHE A 1 408 ? 122.600 115.243 122.985 1.00 67.74  ? 399 PHE A CA     1 
ATOM   4686 C C      . PHE A 1 408 ? 121.781 114.443 121.983 1.00 67.74  ? 399 PHE A C      1 
ATOM   4687 O O      . PHE A 1 408 ? 121.037 113.532 122.365 1.00 67.74  ? 399 PHE A O      1 
ATOM   4688 C CB     . PHE A 1 408 ? 121.927 116.584 123.262 1.00 67.74  ? 399 PHE A CB     1 
ATOM   4689 C CG     . PHE A 1 408 ? 120.494 116.632 122.832 1.00 67.74  ? 399 PHE A CG     1 
ATOM   4690 C CD1    . PHE A 1 408 ? 119.512 116.022 123.586 1.00 67.74  ? 399 PHE A CD1    1 
ATOM   4691 C CD2    . PHE A 1 408 ? 120.131 117.283 121.671 1.00 67.74  ? 399 PHE A CD2    1 
ATOM   4692 C CE1    . PHE A 1 408 ? 118.195 116.063 123.187 1.00 67.74  ? 399 PHE A CE1    1 
ATOM   4693 C CE2    . PHE A 1 408 ? 118.815 117.327 121.269 1.00 67.74  ? 399 PHE A CE2    1 
ATOM   4694 C CZ     . PHE A 1 408 ? 117.847 116.717 122.027 1.00 67.74  ? 399 PHE A CZ     1 
ATOM   4695 H H      . PHE A 1 408 ? 124.183 116.276 122.397 1.00 67.74  ? 399 PHE A H      1 
ATOM   4696 H HA     . PHE A 1 408 ? 122.625 114.745 123.817 1.00 67.74  ? 399 PHE A HA     1 
ATOM   4697 H HB2    . PHE A 1 408 ? 121.957 116.760 124.215 1.00 67.74  ? 399 PHE A HB2    1 
ATOM   4698 H HB3    . PHE A 1 408 ? 122.403 117.281 122.783 1.00 67.74  ? 399 PHE A HB3    1 
ATOM   4699 H HD1    . PHE A 1 408 ? 119.742 115.578 124.370 1.00 67.74  ? 399 PHE A HD1    1 
ATOM   4700 H HD2    . PHE A 1 408 ? 120.783 117.698 121.153 1.00 67.74  ? 399 PHE A HD2    1 
ATOM   4701 H HE1    . PHE A 1 408 ? 117.541 115.649 123.703 1.00 67.74  ? 399 PHE A HE1    1 
ATOM   4702 H HE2    . PHE A 1 408 ? 118.583 117.770 120.485 1.00 67.74  ? 399 PHE A HE2    1 
ATOM   4703 H HZ     . PHE A 1 408 ? 116.957 116.746 121.758 1.00 67.74  ? 399 PHE A HZ     1 
ATOM   4704 N N      . ILE A 1 409 ? 121.893 114.772 120.696 1.00 68.77  ? 400 ILE A N      1 
ATOM   4705 C CA     . ILE A 1 409 ? 121.145 114.033 119.686 1.00 68.77  ? 400 ILE A CA     1 
ATOM   4706 C C      . ILE A 1 409 ? 121.639 112.596 119.603 1.00 68.77  ? 400 ILE A C      1 
ATOM   4707 O O      . ILE A 1 409 ? 120.849 111.667 119.402 1.00 68.77  ? 400 ILE A O      1 
ATOM   4708 C CB     . ILE A 1 409 ? 121.234 114.744 118.325 1.00 68.77  ? 400 ILE A CB     1 
ATOM   4709 C CG1    . ILE A 1 409 ? 120.310 115.965 118.316 1.00 68.77  ? 400 ILE A CG1    1 
ATOM   4710 C CG2    . ILE A 1 409 ? 120.880 113.782 117.199 1.00 68.77  ? 400 ILE A CG2    1 
ATOM   4711 C CD1    . ILE A 1 409 ? 120.422 116.826 117.075 1.00 68.77  ? 400 ILE A CD1    1 
ATOM   4712 H H      . ILE A 1 409 ? 122.386 115.406 120.389 1.00 68.77  ? 400 ILE A H      1 
ATOM   4713 H HA     . ILE A 1 409 ? 120.210 114.009 119.946 1.00 68.77  ? 400 ILE A HA     1 
ATOM   4714 H HB     . ILE A 1 409 ? 122.146 115.048 118.195 1.00 68.77  ? 400 ILE A HB     1 
ATOM   4715 H HG12   . ILE A 1 409 ? 119.391 115.661 118.384 1.00 68.77  ? 400 ILE A HG12   1 
ATOM   4716 H HG13   . ILE A 1 409 ? 120.527 116.522 119.078 1.00 68.77  ? 400 ILE A HG13   1 
ATOM   4717 H HG21   . ILE A 1 409 ? 121.625 113.179 117.049 1.00 68.77  ? 400 ILE A HG21   1 
ATOM   4718 H HG22   . ILE A 1 409 ? 120.090 113.277 117.450 1.00 68.77  ? 400 ILE A HG22   1 
ATOM   4719 H HG23   . ILE A 1 409 ? 120.706 114.284 116.390 1.00 68.77  ? 400 ILE A HG23   1 
ATOM   4720 H HD11   . ILE A 1 409 ? 121.360 116.955 116.863 1.00 68.77  ? 400 ILE A HD11   1 
ATOM   4721 H HD12   . ILE A 1 409 ? 119.974 116.382 116.339 1.00 68.77  ? 400 ILE A HD12   1 
ATOM   4722 H HD13   . ILE A 1 409 ? 120.000 117.682 117.248 1.00 68.77  ? 400 ILE A HD13   1 
ATOM   4723 N N      . SER A 1 410 ? 122.948 112.385 119.751 1.00 70.70  ? 401 SER A N      1 
ATOM   4724 C CA     . SER A 1 410 ? 123.473 111.026 119.684 1.00 70.70  ? 401 SER A CA     1 
ATOM   4725 C C      . SER A 1 410 ? 122.928 110.165 120.816 1.00 70.70  ? 401 SER A C      1 
ATOM   4726 O O      . SER A 1 410 ? 122.544 109.011 120.599 1.00 70.70  ? 401 SER A O      1 
ATOM   4727 C CB     . SER A 1 410 ? 124.999 111.051 119.729 1.00 70.70  ? 401 SER A CB     1 
ATOM   4728 O OG     . SER A 1 410 ? 125.462 111.402 121.020 1.00 70.70  ? 401 SER A OG     1 
ATOM   4729 H H      . SER A 1 410 ? 123.538 112.996 119.887 1.00 70.70  ? 401 SER A H      1 
ATOM   4730 H HA     . SER A 1 410 ? 123.204 110.624 118.843 1.00 70.70  ? 401 SER A HA     1 
ATOM   4731 H HB2    . SER A 1 410 ? 125.337 110.170 119.501 1.00 70.70  ? 401 SER A HB2    1 
ATOM   4732 H HB3    . SER A 1 410 ? 125.323 111.705 119.089 1.00 70.70  ? 401 SER A HB3    1 
ATOM   4733 H HG     . SER A 1 410 ? 125.119 112.130 121.259 1.00 70.70  ? 401 SER A HG     1 
ATOM   4734 N N      . ILE A 1 411 ? 122.881 110.711 122.034 1.00 70.95  ? 402 ILE A N      1 
ATOM   4735 C CA     . ILE A 1 411 ? 122.528 109.909 123.201 1.00 70.95  ? 402 ILE A CA     1 
ATOM   4736 C C      . ILE A 1 411 ? 121.049 109.550 123.263 1.00 70.95  ? 402 ILE A C      1 
ATOM   4737 O O      . ILE A 1 411 ? 120.659 108.717 124.089 1.00 70.95  ? 402 ILE A O      1 
ATOM   4738 C CB     . ILE A 1 411 ? 122.956 110.656 124.484 1.00 70.95  ? 402 ILE A CB     1 
ATOM   4739 C CG1    . ILE A 1 411 ? 124.479 110.809 124.516 1.00 70.95  ? 402 ILE A CG1    1 
ATOM   4740 C CG2    . ILE A 1 411 ? 122.477 109.924 125.730 1.00 70.95  ? 402 ILE A CG2    1 
ATOM   4741 C CD1    . ILE A 1 411 ? 125.002 111.638 125.672 1.00 70.95  ? 402 ILE A CD1    1 
ATOM   4742 H H      . ILE A 1 411 ? 123.047 111.537 122.207 1.00 70.95  ? 402 ILE A H      1 
ATOM   4743 H HA     . ILE A 1 411 ? 123.028 109.078 123.166 1.00 70.95  ? 402 ILE A HA     1 
ATOM   4744 H HB     . ILE A 1 411 ? 122.557 111.541 124.474 1.00 70.95  ? 402 ILE A HB     1 
ATOM   4745 H HG12   . ILE A 1 411 ? 124.877 109.927 124.584 1.00 70.95  ? 402 ILE A HG12   1 
ATOM   4746 H HG13   . ILE A 1 411 ? 124.770 111.234 123.695 1.00 70.95  ? 402 ILE A HG13   1 
ATOM   4747 H HG21   . ILE A 1 411 ? 122.956 110.252 126.505 1.00 70.95  ? 402 ILE A HG21   1 
ATOM   4748 H HG22   . ILE A 1 411 ? 121.528 110.086 125.846 1.00 70.95  ? 402 ILE A HG22   1 
ATOM   4749 H HG23   . ILE A 1 411 ? 122.640 108.975 125.620 1.00 70.95  ? 402 ILE A HG23   1 
ATOM   4750 H HD11   . ILE A 1 411 ? 124.419 112.403 125.800 1.00 70.95  ? 402 ILE A HD11   1 
ATOM   4751 H HD12   . ILE A 1 411 ? 125.901 111.937 125.464 1.00 70.95  ? 402 ILE A HD12   1 
ATOM   4752 H HD13   . ILE A 1 411 ? 125.012 111.093 126.474 1.00 70.95  ? 402 ILE A HD13   1 
ATOM   4753 N N      . MET A 1 412 ? 120.215 110.128 122.398 1.00 70.86  ? 403 MET A N      1 
ATOM   4754 C CA     . MET A 1 412 ? 118.769 110.022 122.579 1.00 70.86  ? 403 MET A CA     1 
ATOM   4755 C C      . MET A 1 412 ? 118.289 108.579 122.469 1.00 70.86  ? 403 MET A C      1 
ATOM   4756 O O      . MET A 1 412 ? 117.697 108.035 123.407 1.00 70.86  ? 403 MET A O      1 
ATOM   4757 C CB     . MET A 1 412 ? 118.048 110.903 121.559 1.00 70.86  ? 403 MET A CB     1 
ATOM   4758 C CG     . MET A 1 412 ? 116.563 111.052 121.836 1.00 70.86  ? 403 MET A CG     1 
ATOM   4759 S SD     . MET A 1 412 ? 115.751 112.224 120.738 1.00 70.86  ? 403 MET A SD     1 
ATOM   4760 C CE     . MET A 1 412 ? 115.855 111.359 119.175 1.00 70.86  ? 403 MET A CE     1 
ATOM   4761 H H      . MET A 1 412 ? 120.456 110.582 121.708 1.00 70.86  ? 403 MET A H      1 
ATOM   4762 H HA     . MET A 1 412 ? 118.545 110.355 123.462 1.00 70.86  ? 403 MET A HA     1 
ATOM   4763 H HB2    . MET A 1 412 ? 118.444 111.789 121.573 1.00 70.86  ? 403 MET A HB2    1 
ATOM   4764 H HB3    . MET A 1 412 ? 118.149 110.510 120.678 1.00 70.86  ? 403 MET A HB3    1 
ATOM   4765 H HG2    . MET A 1 412 ? 116.133 110.190 121.722 1.00 70.86  ? 403 MET A HG2    1 
ATOM   4766 H HG3    . MET A 1 412 ? 116.443 111.364 122.746 1.00 70.86  ? 403 MET A HG3    1 
ATOM   4767 H HE1    . MET A 1 412 ? 116.788 111.206 118.960 1.00 70.86  ? 403 MET A HE1    1 
ATOM   4768 H HE2    . MET A 1 412 ? 115.442 111.903 118.486 1.00 70.86  ? 403 MET A HE2    1 
ATOM   4769 H HE3    . MET A 1 412 ? 115.389 110.511 119.251 1.00 70.86  ? 403 MET A HE3    1 
ATOM   4770 N N      . ALA A 1 413 ? 118.531 107.941 121.325 1.00 71.25  ? 404 ALA A N      1 
ATOM   4771 C CA     . ALA A 1 413 ? 117.897 106.655 121.034 1.00 71.25  ? 404 ALA A CA     1 
ATOM   4772 C C      . ALA A 1 413 ? 118.113 105.607 122.119 1.00 71.25  ? 404 ALA A C      1 
ATOM   4773 O O      . ALA A 1 413 ? 117.141 104.930 122.489 1.00 71.25  ? 404 ALA A O      1 
ATOM   4774 C CB     . ALA A 1 413 ? 118.390 106.140 119.675 1.00 71.25  ? 404 ALA A CB     1 
ATOM   4775 H H      . ALA A 1 413 ? 119.054 108.227 120.705 1.00 71.25  ? 404 ALA A H      1 
ATOM   4776 H HA     . ALA A 1 413 ? 116.940 106.799 120.959 1.00 71.25  ? 404 ALA A HA     1 
ATOM   4777 H HB1    . ALA A 1 413 ? 118.060 106.730 118.979 1.00 71.25  ? 404 ALA A HB1    1 
ATOM   4778 H HB2    . ALA A 1 413 ? 118.045 105.244 119.537 1.00 71.25  ? 404 ALA A HB2    1 
ATOM   4779 H HB3    . ALA A 1 413 ? 119.358 106.126 119.663 1.00 71.25  ? 404 ALA A HB3    1 
ATOM   4780 N N      . PRO A 1 414 ? 119.319 105.410 122.657 1.00 70.94  ? 405 PRO A N      1 
ATOM   4781 C CA     . PRO A 1 414 ? 119.473 104.399 123.719 1.00 70.94  ? 405 PRO A CA     1 
ATOM   4782 C C      . PRO A 1 414 ? 118.566 104.632 124.915 1.00 70.94  ? 405 PRO A C      1 
ATOM   4783 O O      . PRO A 1 414 ? 118.022 103.670 125.479 1.00 70.94  ? 405 PRO A O      1 
ATOM   4784 C CB     . PRO A 1 414 ? 120.955 104.517 124.093 1.00 70.94  ? 405 PRO A CB     1 
ATOM   4785 C CG     . PRO A 1 414 ? 121.609 105.040 122.865 1.00 70.94  ? 405 PRO A CG     1 
ATOM   4786 C CD     . PRO A 1 414 ? 120.615 105.970 122.240 1.00 70.94  ? 405 PRO A CD     1 
ATOM   4787 H HA     . PRO A 1 414 ? 119.306 103.517 123.362 1.00 70.94  ? 405 PRO A HA     1 
ATOM   4788 H HB2    . PRO A 1 414 ? 121.060 105.139 124.830 1.00 70.94  ? 405 PRO A HB2    1 
ATOM   4789 H HB3    . PRO A 1 414 ? 121.307 103.644 124.325 1.00 70.94  ? 405 PRO A HB3    1 
ATOM   4790 H HG2    . PRO A 1 414 ? 122.418 105.518 123.106 1.00 70.94  ? 405 PRO A HG2    1 
ATOM   4791 H HG3    . PRO A 1 414 ? 121.811 104.305 122.265 1.00 70.94  ? 405 PRO A HG3    1 
ATOM   4792 H HD2    . PRO A 1 414 ? 120.726 106.868 122.588 1.00 70.94  ? 405 PRO A HD2    1 
ATOM   4793 H HD3    . PRO A 1 414 ? 120.706 105.950 121.277 1.00 70.94  ? 405 PRO A HD3    1 
ATOM   4794 N N      . ILE A 1 415 ? 118.376 105.891 125.315 1.00 69.86  ? 406 ILE A N      1 
ATOM   4795 C CA     . ILE A 1 415 ? 117.493 106.179 126.440 1.00 69.86  ? 406 ILE A CA     1 
ATOM   4796 C C      . ILE A 1 415 ? 116.091 105.668 126.156 1.00 69.86  ? 406 ILE A C      1 
ATOM   4797 O O      . ILE A 1 415 ? 115.353 105.307 127.080 1.00 69.86  ? 406 ILE A O      1 
ATOM   4798 C CB     . ILE A 1 415 ? 117.486 107.689 126.742 1.00 69.86  ? 406 ILE A CB     1 
ATOM   4799 C CG1    . ILE A 1 415 ? 118.873 108.145 127.197 1.00 69.86  ? 406 ILE A CG1    1 
ATOM   4800 C CG2    . ILE A 1 415 ? 116.438 108.006 127.797 1.00 69.86  ? 406 ILE A CG2    1 
ATOM   4801 C CD1    . ILE A 1 415 ? 119.006 109.647 127.350 1.00 69.86  ? 406 ILE A CD1    1 
ATOM   4802 H H      . ILE A 1 415 ? 118.741 106.583 124.957 1.00 69.86  ? 406 ILE A H      1 
ATOM   4803 H HA     . ILE A 1 415 ? 117.826 105.719 127.226 1.00 69.86  ? 406 ILE A HA     1 
ATOM   4804 H HB     . ILE A 1 415 ? 117.258 108.165 125.929 1.00 69.86  ? 406 ILE A HB     1 
ATOM   4805 H HG12   . ILE A 1 415 ? 119.067 107.742 128.058 1.00 69.86  ? 406 ILE A HG12   1 
ATOM   4806 H HG13   . ILE A 1 415 ? 119.529 107.856 126.544 1.00 69.86  ? 406 ILE A HG13   1 
ATOM   4807 H HG21   . ILE A 1 415 ? 115.557 107.949 127.396 1.00 69.86  ? 406 ILE A HG21   1 
ATOM   4808 H HG22   . ILE A 1 415 ? 116.581 108.903 128.135 1.00 69.86  ? 406 ILE A HG22   1 
ATOM   4809 H HG23   . ILE A 1 415 ? 116.515 107.365 128.521 1.00 69.86  ? 406 ILE A HG23   1 
ATOM   4810 H HD11   . ILE A 1 415 ? 119.945 109.870 127.449 1.00 69.86  ? 406 ILE A HD11   1 
ATOM   4811 H HD12   . ILE A 1 415 ? 118.645 110.078 126.560 1.00 69.86  ? 406 ILE A HD12   1 
ATOM   4812 H HD13   . ILE A 1 415 ? 118.516 109.933 128.137 1.00 69.86  ? 406 ILE A HD13   1 
ATOM   4813 N N      . ALA A 1 416 ? 115.701 105.621 124.881 1.00 70.00  ? 407 ALA A N      1 
ATOM   4814 C CA     . ALA A 1 416 ? 114.350 105.192 124.540 1.00 70.00  ? 407 ALA A CA     1 
ATOM   4815 C C      . ALA A 1 416 ? 114.087 103.773 125.025 1.00 70.00  ? 407 ALA A C      1 
ATOM   4816 O O      . ALA A 1 416 ? 113.104 103.521 125.731 1.00 70.00  ? 407 ALA A O      1 
ATOM   4817 C CB     . ALA A 1 416 ? 114.135 105.293 123.031 1.00 70.00  ? 407 ALA A CB     1 
ATOM   4818 H H      . ALA A 1 416 ? 116.191 105.831 124.207 1.00 70.00  ? 407 ALA A H      1 
ATOM   4819 H HA     . ALA A 1 416 ? 113.713 105.780 124.975 1.00 70.00  ? 407 ALA A HA     1 
ATOM   4820 H HB1    . ALA A 1 416 ? 114.312 106.204 122.749 1.00 70.00  ? 407 ALA A HB1    1 
ATOM   4821 H HB2    . ALA A 1 416 ? 113.217 105.056 122.827 1.00 70.00  ? 407 ALA A HB2    1 
ATOM   4822 H HB3    . ALA A 1 416 ? 114.742 104.684 122.583 1.00 70.00  ? 407 ALA A HB3    1 
ATOM   4823 N N      . PHE A 1 417 ? 114.961 102.828 124.669 1.00 71.03  ? 408 PHE A N      1 
ATOM   4824 C CA     . PHE A 1 417 ? 114.755 101.454 125.108 1.00 71.03  ? 408 PHE A CA     1 
ATOM   4825 C C      . PHE A 1 417 ? 115.311 101.193 126.499 1.00 71.03  ? 408 PHE A C      1 
ATOM   4826 O O      . PHE A 1 417 ? 115.060 100.117 127.053 1.00 71.03  ? 408 PHE A O      1 
ATOM   4827 C CB     . PHE A 1 417 ? 115.358 100.457 124.108 1.00 71.03  ? 408 PHE A CB     1 
ATOM   4828 C CG     . PHE A 1 417 ? 116.851 100.553 123.947 1.00 71.03  ? 408 PHE A CG     1 
ATOM   4829 C CD1    . PHE A 1 417 ? 117.708 100.135 124.952 1.00 71.03  ? 408 PHE A CD1    1 
ATOM   4830 C CD2    . PHE A 1 417 ? 117.396 101.016 122.764 1.00 71.03  ? 408 PHE A CD2    1 
ATOM   4831 C CE1    . PHE A 1 417 ? 119.077 100.210 124.791 1.00 71.03  ? 408 PHE A CE1    1 
ATOM   4832 C CE2    . PHE A 1 417 ? 118.763 101.086 122.596 1.00 71.03  ? 408 PHE A CE2    1 
ATOM   4833 C CZ     . PHE A 1 417 ? 119.604 100.685 123.611 1.00 71.03  ? 408 PHE A CZ     1 
ATOM   4834 H H      . PHE A 1 417 ? 115.662 102.955 124.188 1.00 71.03  ? 408 PHE A H      1 
ATOM   4835 H HA     . PHE A 1 417 ? 113.801 101.285 125.142 1.00 71.03  ? 408 PHE A HA     1 
ATOM   4836 H HB2    . PHE A 1 417 ? 115.153 99.557  124.407 1.00 71.03  ? 408 PHE A HB2    1 
ATOM   4837 H HB3    . PHE A 1 417 ? 114.961 100.610 123.238 1.00 71.03  ? 408 PHE A HB3    1 
ATOM   4838 H HD1    . PHE A 1 417 ? 117.357 99.815  125.752 1.00 71.03  ? 408 PHE A HD1    1 
ATOM   4839 H HD2    . PHE A 1 417 ? 116.834 101.290 122.076 1.00 71.03  ? 408 PHE A HD2    1 
ATOM   4840 H HE1    . PHE A 1 417 ? 119.642 99.935  125.476 1.00 71.03  ? 408 PHE A HE1    1 
ATOM   4841 H HE2    . PHE A 1 417 ? 119.117 101.410 121.799 1.00 71.03  ? 408 PHE A HE2    1 
ATOM   4842 H HZ     . PHE A 1 417 ? 120.526 100.735 123.499 1.00 71.03  ? 408 PHE A HZ     1 
ATOM   4843 N N      . GLU A 1 418 ? 116.062 102.134 127.074 1.00 70.96  ? 409 GLU A N      1 
ATOM   4844 C CA     . GLU A 1 418 ? 116.381 102.027 128.494 1.00 70.96  ? 409 GLU A CA     1 
ATOM   4845 C C      . GLU A 1 418 ? 115.156 102.326 129.350 1.00 70.96  ? 409 GLU A C      1 
ATOM   4846 O O      . GLU A 1 418 ? 114.908 101.643 130.350 1.00 70.96  ? 409 GLU A O      1 
ATOM   4847 C CB     . GLU A 1 418 ? 117.532 102.969 128.848 1.00 70.96  ? 409 GLU A CB     1 
ATOM   4848 C CG     . GLU A 1 418 ? 117.691 103.252 130.341 1.00 70.96  ? 409 GLU A CG     1 
ATOM   4849 C CD     . GLU A 1 418 ? 117.796 101.992 131.181 1.00 70.96  ? 409 GLU A CD     1 
ATOM   4850 O OE1    . GLU A 1 418 ? 117.987 100.899 130.608 1.00 70.96  ? 409 GLU A OE1    1 
ATOM   4851 O OE2    . GLU A 1 418 ? 117.688 102.096 132.420 1.00 70.96  ? 409 GLU A OE2    1 
ATOM   4852 H H      . GLU A 1 418 ? 116.390 102.823 126.678 1.00 70.96  ? 409 GLU A H      1 
ATOM   4853 H HA     . GLU A 1 418 ? 116.663 101.118 128.681 1.00 70.96  ? 409 GLU A HA     1 
ATOM   4854 H HB2    . GLU A 1 418 ? 118.360 102.575 128.534 1.00 70.96  ? 409 GLU A HB2    1 
ATOM   4855 H HB3    . GLU A 1 418 ? 117.384 103.818 128.403 1.00 70.96  ? 409 GLU A HB3    1 
ATOM   4856 H HG2    . GLU A 1 418 ? 118.505 103.762 130.475 1.00 70.96  ? 409 GLU A HG2    1 
ATOM   4857 H HG3    . GLU A 1 418 ? 116.930 103.763 130.656 1.00 70.96  ? 409 GLU A HG3    1 
ATOM   4858 N N      . LEU A 1 419 ? 114.374 103.340 128.969 1.00 67.83  ? 410 LEU A N      1 
ATOM   4859 C CA     . LEU A 1 419 ? 113.204 103.725 129.752 1.00 67.83  ? 410 LEU A CA     1 
ATOM   4860 C C      . LEU A 1 419 ? 112.040 102.764 129.549 1.00 67.83  ? 410 LEU A C      1 
ATOM   4861 O O      . LEU A 1 419 ? 111.292 102.486 130.492 1.00 67.83  ? 410 LEU A O      1 
ATOM   4862 C CB     . LEU A 1 419 ? 112.775 105.145 129.383 1.00 67.83  ? 410 LEU A CB     1 
ATOM   4863 C CG     . LEU A 1 419 ? 113.696 106.276 129.841 1.00 67.83  ? 410 LEU A CG     1 
ATOM   4864 C CD1    . LEU A 1 419 ? 113.321 107.576 129.152 1.00 67.83  ? 410 LEU A CD1    1 
ATOM   4865 C CD2    . LEU A 1 419 ? 113.633 106.439 131.348 1.00 67.83  ? 410 LEU A CD2    1 
ATOM   4866 H H      . LEU A 1 419 ? 114.500 103.816 128.264 1.00 67.83  ? 410 LEU A H      1 
ATOM   4867 H HA     . LEU A 1 419 ? 113.438 103.716 130.693 1.00 67.83  ? 410 LEU A HA     1 
ATOM   4868 H HB2    . LEU A 1 419 ? 112.710 105.201 128.417 1.00 67.83  ? 410 LEU A HB2    1 
ATOM   4869 H HB3    . LEU A 1 419 ? 111.902 105.309 129.774 1.00 67.83  ? 410 LEU A HB3    1 
ATOM   4870 H HG     . LEU A 1 419 ? 114.610 106.059 129.599 1.00 67.83  ? 410 LEU A HG     1 
ATOM   4871 H HD11   . LEU A 1 419 ? 113.425 107.467 128.194 1.00 67.83  ? 410 LEU A HD11   1 
ATOM   4872 H HD12   . LEU A 1 419 ? 113.906 108.282 129.470 1.00 67.83  ? 410 LEU A HD12   1 
ATOM   4873 H HD13   . LEU A 1 419 ? 112.398 107.790 129.363 1.00 67.83  ? 410 LEU A HD13   1 
ATOM   4874 H HD21   . LEU A 1 419 ? 112.709 106.574 131.611 1.00 67.83  ? 410 LEU A HD21   1 
ATOM   4875 H HD22   . LEU A 1 419 ? 114.165 107.208 131.605 1.00 67.83  ? 410 LEU A HD22   1 
ATOM   4876 H HD23   . LEU A 1 419 ? 113.983 105.638 131.769 1.00 67.83  ? 410 LEU A HD23   1 
ATOM   4877 N N      . VAL A 1 420 ? 111.869 102.253 128.330 1.00 69.79  ? 411 VAL A N      1 
ATOM   4878 C CA     . VAL A 1 420 ? 110.718 101.436 127.973 1.00 69.79  ? 411 VAL A CA     1 
ATOM   4879 C C      . VAL A 1 420 ? 111.207 100.158 127.307 1.00 69.79  ? 411 VAL A C      1 
ATOM   4880 O O      . VAL A 1 420 ? 112.303 100.098 126.747 1.00 69.79  ? 411 VAL A O      1 
ATOM   4881 C CB     . VAL A 1 420 ? 109.746 102.192 127.040 1.00 69.79  ? 411 VAL A CB     1 
ATOM   4882 C CG1    . VAL A 1 420 ? 108.586 101.304 126.631 1.00 69.79  ? 411 VAL A CG1    1 
ATOM   4883 C CG2    . VAL A 1 420 ? 109.236 103.451 127.718 1.00 69.79  ? 411 VAL A CG2    1 
ATOM   4884 H H      . VAL A 1 420 ? 112.420 102.370 127.681 1.00 69.79  ? 411 VAL A H      1 
ATOM   4885 H HA     . VAL A 1 420 ? 110.235 101.191 128.777 1.00 69.79  ? 411 VAL A HA     1 
ATOM   4886 H HB     . VAL A 1 420 ? 110.220 102.455 126.236 1.00 69.79  ? 411 VAL A HB     1 
ATOM   4887 H HG11   . VAL A 1 420 ? 108.890 100.677 125.956 1.00 69.79  ? 411 VAL A HG11   1 
ATOM   4888 H HG12   . VAL A 1 420 ? 107.879 101.859 126.268 1.00 69.79  ? 411 VAL A HG12   1 
ATOM   4889 H HG13   . VAL A 1 420 ? 108.263 100.825 127.410 1.00 69.79  ? 411 VAL A HG13   1 
ATOM   4890 H HG21   . VAL A 1 420 ? 108.642 103.918 127.109 1.00 69.79  ? 411 VAL A HG21   1 
ATOM   4891 H HG22   . VAL A 1 420 ? 108.757 103.204 128.524 1.00 69.79  ? 411 VAL A HG22   1 
ATOM   4892 H HG23   . VAL A 1 420 ? 109.991 104.018 127.942 1.00 69.79  ? 411 VAL A HG23   1 
ATOM   4893 N N      . GLY A 1 421 ? 110.368 99.127  127.375 1.00 71.22  ? 412 GLY A N      1 
ATOM   4894 C CA     . GLY A 1 421 ? 110.706 97.864  126.751 1.00 71.22  ? 412 GLY A CA     1 
ATOM   4895 C C      . GLY A 1 421 ? 110.945 98.008  125.261 1.00 71.22  ? 412 GLY A C      1 
ATOM   4896 O O      . GLY A 1 421 ? 110.512 98.963  124.615 1.00 71.22  ? 412 GLY A O      1 
ATOM   4897 H H      . GLY A 1 421 ? 109.607 99.138  127.774 1.00 71.22  ? 412 GLY A H      1 
ATOM   4898 H HA2    . GLY A 1 421 ? 111.508 97.504  127.160 1.00 71.22  ? 412 GLY A HA2    1 
ATOM   4899 H HA3    . GLY A 1 421 ? 109.982 97.233  126.886 1.00 71.22  ? 412 GLY A HA3    1 
ATOM   4900 N N      . ALA A 1 422 ? 111.661 97.025  124.709 1.00 71.39  ? 413 ALA A N      1 
ATOM   4901 C CA     . ALA A 1 422 ? 112.036 97.083  123.300 1.00 71.39  ? 413 ALA A CA     1 
ATOM   4902 C C      . ALA A 1 422 ? 110.816 97.110  122.388 1.00 71.39  ? 413 ALA A C      1 
ATOM   4903 O O      . ALA A 1 422 ? 110.866 97.701  121.304 1.00 71.39  ? 413 ALA A O      1 
ATOM   4904 C CB     . ALA A 1 422 ? 112.929 95.893  122.950 1.00 71.39  ? 413 ALA A CB     1 
ATOM   4905 H H      . ALA A 1 422 ? 111.937 96.325  125.125 1.00 71.39  ? 413 ALA A H      1 
ATOM   4906 H HA     . ALA A 1 422 ? 112.544 97.893  123.144 1.00 71.39  ? 413 ALA A HA     1 
ATOM   4907 H HB1    . ALA A 1 422 ? 113.725 95.924  123.503 1.00 71.39  ? 413 ALA A HB1    1 
ATOM   4908 H HB2    . ALA A 1 422 ? 112.440 95.073  123.118 1.00 71.39  ? 413 ALA A HB2    1 
ATOM   4909 H HB3    . ALA A 1 422 ? 113.174 95.948  122.013 1.00 71.39  ? 413 ALA A HB3    1 
ATOM   4910 N N      . GLN A 1 423 ? 109.716 96.482  122.805 1.00 69.80  ? 414 GLN A N      1 
ATOM   4911 C CA     . GLN A 1 423 ? 108.549 96.385  121.935 1.00 69.80  ? 414 GLN A CA     1 
ATOM   4912 C C      . GLN A 1 423 ? 107.933 97.753  121.670 1.00 69.80  ? 414 GLN A C      1 
ATOM   4913 O O      . GLN A 1 423 ? 107.501 98.036  120.547 1.00 69.80  ? 414 GLN A O      1 
ATOM   4914 C CB     . GLN A 1 423 ? 107.512 95.447  122.550 1.00 69.80  ? 414 GLN A CB     1 
ATOM   4915 C CG     . GLN A 1 423 ? 107.885 93.973  122.498 1.00 69.80  ? 414 GLN A CG     1 
ATOM   4916 C CD     . GLN A 1 423 ? 109.055 93.628  123.398 1.00 69.80  ? 414 GLN A CD     1 
ATOM   4917 O OE1    . GLN A 1 423 ? 109.813 94.503  123.815 1.00 69.80  ? 414 GLN A OE1    1 
ATOM   4918 N NE2    . GLN A 1 423 ? 109.204 92.345  123.704 1.00 69.80  ? 414 GLN A NE2    1 
ATOM   4919 H H      . GLN A 1 423 ? 109.620 96.119  123.578 1.00 69.80  ? 414 GLN A H      1 
ATOM   4920 H HA     . GLN A 1 423 ? 108.823 96.010  121.083 1.00 69.80  ? 414 GLN A HA     1 
ATOM   4921 H HB2    . GLN A 1 423 ? 107.388 95.687  123.482 1.00 69.80  ? 414 GLN A HB2    1 
ATOM   4922 H HB3    . GLN A 1 423 ? 106.675 95.555  122.072 1.00 69.80  ? 414 GLN A HB3    1 
ATOM   4923 H HG2    . GLN A 1 423 ? 107.123 93.445  122.781 1.00 69.80  ? 414 GLN A HG2    1 
ATOM   4924 H HG3    . GLN A 1 423 ? 108.129 93.742  121.588 1.00 69.80  ? 414 GLN A HG3    1 
ATOM   4925 H HE21   . GLN A 1 423 ? 108.654 91.762  123.394 1.00 69.80  ? 414 GLN A HE21   1 
ATOM   4926 H HE22   . GLN A 1 423 ? 109.853 92.097  124.212 1.00 69.80  ? 414 GLN A HE22   1 
ATOM   4927 N N      . ASP A 1 424 ? 107.885 98.613  122.684 1.00 69.40  ? 415 ASP A N      1 
ATOM   4928 C CA     . ASP A 1 424 ? 107.202 99.896  122.590 1.00 69.40  ? 415 ASP A CA     1 
ATOM   4929 C C      . ASP A 1 424 ? 108.131 101.041 122.208 1.00 69.40  ? 415 ASP A C      1 
ATOM   4930 O O      . ASP A 1 424 ? 107.713 102.202 122.265 1.00 69.40  ? 415 ASP A O      1 
ATOM   4931 C CB     . ASP A 1 424 ? 106.513 100.219 123.918 1.00 69.40  ? 415 ASP A CB     1 
ATOM   4932 C CG     . ASP A 1 424 ? 105.361 99.285  124.218 1.00 69.40  ? 415 ASP A CG     1 
ATOM   4933 O OD1    . ASP A 1 424 ? 104.581 98.982  123.293 1.00 69.40  ? 415 ASP A OD1    1 
ATOM   4934 O OD2    . ASP A 1 424 ? 105.238 98.850  125.380 1.00 69.40  ? 415 ASP A OD2    1 
ATOM   4935 H H      . ASP A 1 424 ? 108.248 98.472  123.451 1.00 69.40  ? 415 ASP A H      1 
ATOM   4936 H HA     . ASP A 1 424 ? 106.515 99.835  121.909 1.00 69.40  ? 415 ASP A HA     1 
ATOM   4937 H HB2    . ASP A 1 424 ? 107.159 100.135 124.635 1.00 69.40  ? 415 ASP A HB2    1 
ATOM   4938 H HB3    . ASP A 1 424 ? 106.167 101.124 123.885 1.00 69.40  ? 415 ASP A HB3    1 
ATOM   4939 N N      . VAL A 1 425 ? 109.376 100.750 121.829 1.00 68.58  ? 416 VAL A N      1 
ATOM   4940 C CA     . VAL A 1 425 ? 110.296 101.816 121.445 1.00 68.58  ? 416 VAL A CA     1 
ATOM   4941 C C      . VAL A 1 425 ? 109.767 102.565 120.230 1.00 68.58  ? 416 VAL A C      1 
ATOM   4942 O O      . VAL A 1 425 ? 109.920 103.787 120.122 1.00 68.58  ? 416 VAL A O      1 
ATOM   4943 C CB     . VAL A 1 425 ? 111.701 101.244 121.183 1.00 68.58  ? 416 VAL A CB     1 
ATOM   4944 C CG1    . VAL A 1 425 ? 112.591 102.298 120.548 1.00 68.58  ? 416 VAL A CG1    1 
ATOM   4945 C CG2    . VAL A 1 425 ? 112.313 100.742 122.476 1.00 68.58  ? 416 VAL A CG2    1 
ATOM   4946 H H      . VAL A 1 425 ? 109.706 99.957  121.787 1.00 68.58  ? 416 VAL A H      1 
ATOM   4947 H HA     . VAL A 1 425 ? 110.365 102.448 122.177 1.00 68.58  ? 416 VAL A HA     1 
ATOM   4948 H HB     . VAL A 1 425 ? 111.632 100.496 120.570 1.00 68.58  ? 416 VAL A HB     1 
ATOM   4949 H HG11   . VAL A 1 425 ? 113.510 102.134 120.809 1.00 68.58  ? 416 VAL A HG11   1 
ATOM   4950 H HG12   . VAL A 1 425 ? 112.314 103.176 120.853 1.00 68.58  ? 416 VAL A HG12   1 
ATOM   4951 H HG13   . VAL A 1 425 ? 112.510 102.239 119.583 1.00 68.58  ? 416 VAL A HG13   1 
ATOM   4952 H HG21   . VAL A 1 425 ? 111.605 100.535 123.104 1.00 68.58  ? 416 VAL A HG21   1 
ATOM   4953 H HG22   . VAL A 1 425 ? 112.833 99.946  122.287 1.00 68.58  ? 416 VAL A HG22   1 
ATOM   4954 H HG23   . VAL A 1 425 ? 112.888 101.432 122.842 1.00 68.58  ? 416 VAL A HG23   1 
ATOM   4955 N N      . SER A 1 426 ? 109.152 101.846 119.289 1.00 68.63  ? 417 SER A N      1 
ATOM   4956 C CA     . SER A 1 426 ? 108.634 102.494 118.088 1.00 68.63  ? 417 SER A CA     1 
ATOM   4957 C C      . SER A 1 426 ? 107.538 103.495 118.435 1.00 68.63  ? 417 SER A C      1 
ATOM   4958 O O      . SER A 1 426 ? 107.561 104.644 117.978 1.00 68.63  ? 417 SER A O      1 
ATOM   4959 C CB     . SER A 1 426 ? 108.112 101.438 117.113 1.00 68.63  ? 417 SER A CB     1 
ATOM   4960 O OG     . SER A 1 426 ? 107.118 100.634 117.722 1.00 68.63  ? 417 SER A OG     1 
ATOM   4961 H H      . SER A 1 426 ? 109.025 100.996 119.323 1.00 68.63  ? 417 SER A H      1 
ATOM   4962 H HA     . SER A 1 426 ? 109.354 102.976 117.653 1.00 68.63  ? 417 SER A HA     1 
ATOM   4963 H HB2    . SER A 1 426 ? 107.729 101.884 116.341 1.00 68.63  ? 417 SER A HB2    1 
ATOM   4964 H HB3    . SER A 1 426 ? 108.850 100.873 116.837 1.00 68.63  ? 417 SER A HB3    1 
ATOM   4965 H HG     . SER A 1 426 ? 106.846 100.055 117.178 1.00 68.63  ? 417 SER A HG     1 
ATOM   4966 N N      . GLN A 1 427 ? 106.569 103.076 119.251 1.00 67.25  ? 418 GLN A N      1 
ATOM   4967 C CA     . GLN A 1 427 ? 105.517 103.994 119.672 1.00 67.25  ? 418 GLN A CA     1 
ATOM   4968 C C      . GLN A 1 427 ? 106.097 105.151 120.471 1.00 67.25  ? 418 GLN A C      1 
ATOM   4969 O O      . GLN A 1 427 ? 105.646 106.297 120.339 1.00 67.25  ? 418 GLN A O      1 
ATOM   4970 C CB     . GLN A 1 427 ? 104.470 103.250 120.499 1.00 67.25  ? 418 GLN A CB     1 
ATOM   4971 C CG     . GLN A 1 427 ? 103.787 102.105 119.773 1.00 67.25  ? 418 GLN A CG     1 
ATOM   4972 C CD     . GLN A 1 427 ? 102.873 102.574 118.662 1.00 67.25  ? 418 GLN A CD     1 
ATOM   4973 O OE1    . GLN A 1 427 ? 102.931 103.727 118.240 1.00 67.25  ? 418 GLN A OE1    1 
ATOM   4974 N NE2    . GLN A 1 427 ? 102.018 101.680 118.183 1.00 67.25  ? 418 GLN A NE2    1 
ATOM   4975 H H      . GLN A 1 427 ? 106.500 102.279 119.568 1.00 67.25  ? 418 GLN A H      1 
ATOM   4976 H HA     . GLN A 1 427 ? 105.085 104.361 118.886 1.00 67.25  ? 418 GLN A HA     1 
ATOM   4977 H HB2    . GLN A 1 427 ? 104.900 102.883 121.287 1.00 67.25  ? 418 GLN A HB2    1 
ATOM   4978 H HB3    . GLN A 1 427 ? 103.782 103.880 120.767 1.00 67.25  ? 418 GLN A HB3    1 
ATOM   4979 H HG2    . GLN A 1 427 ? 104.462 101.529 119.383 1.00 67.25  ? 418 GLN A HG2    1 
ATOM   4980 H HG3    . GLN A 1 427 ? 103.251 101.604 120.409 1.00 67.25  ? 418 GLN A HG3    1 
ATOM   4981 H HE21   . GLN A 1 427 ? 102.006 100.882 118.503 1.00 67.25  ? 418 GLN A HE21   1 
ATOM   4982 H HE22   . GLN A 1 427 ? 101.477 101.898 117.551 1.00 67.25  ? 418 GLN A HE22   1 
ATOM   4983 N N      . ALA A 1 428 ? 107.091 104.871 121.316 1.00 67.64  ? 419 ALA A N      1 
ATOM   4984 C CA     . ALA A 1 428 ? 107.717 105.930 122.095 1.00 67.64  ? 419 ALA A CA     1 
ATOM   4985 C C      . ALA A 1 428 ? 108.322 106.987 121.184 1.00 67.64  ? 419 ALA A C      1 
ATOM   4986 O O      . ALA A 1 428 ? 108.108 108.189 121.375 1.00 67.64  ? 419 ALA A O      1 
ATOM   4987 C CB     . ALA A 1 428 ? 108.785 105.336 123.012 1.00 67.64  ? 419 ALA A CB     1 
ATOM   4988 H H      . ALA A 1 428 ? 107.414 104.086 121.452 1.00 67.64  ? 419 ALA A H      1 
ATOM   4989 H HA     . ALA A 1 428 ? 107.044 106.355 122.649 1.00 67.64  ? 419 ALA A HA     1 
ATOM   4990 H HB1    . ALA A 1 428 ? 108.354 104.799 123.695 1.00 67.64  ? 419 ALA A HB1    1 
ATOM   4991 H HB2    . ALA A 1 428 ? 109.286 106.057 123.421 1.00 67.64  ? 419 ALA A HB2    1 
ATOM   4992 H HB3    . ALA A 1 428 ? 109.382 104.785 122.482 1.00 67.64  ? 419 ALA A HB3    1 
ATOM   4993 N N      . ILE A 1 429 ? 109.073 106.550 120.174 1.00 66.93  ? 420 ILE A N      1 
ATOM   4994 C CA     . ILE A 1 429 ? 109.700 107.491 119.255 1.00 66.93  ? 420 ILE A CA     1 
ATOM   4995 C C      . ILE A 1 429 ? 108.642 108.244 118.462 1.00 66.93  ? 420 ILE A C      1 
ATOM   4996 O O      . ILE A 1 429 ? 108.776 109.448 118.208 1.00 66.93  ? 420 ILE A O      1 
ATOM   4997 C CB     . ILE A 1 429 ? 110.684 106.755 118.330 1.00 66.93  ? 420 ILE A CB     1 
ATOM   4998 C CG1    . ILE A 1 429 ? 111.877 106.223 119.132 1.00 66.93  ? 420 ILE A CG1    1 
ATOM   4999 C CG2    . ILE A 1 429 ? 111.148 107.673 117.212 1.00 66.93  ? 420 ILE A CG2    1 
ATOM   5000 C CD1    . ILE A 1 429 ? 112.722 107.300 119.796 1.00 66.93  ? 420 ILE A CD1    1 
ATOM   5001 H H      . ILE A 1 429 ? 109.233 105.723 120.002 1.00 66.93  ? 420 ILE A H      1 
ATOM   5002 H HA     . ILE A 1 429 ? 110.196 108.147 119.768 1.00 66.93  ? 420 ILE A HA     1 
ATOM   5003 H HB     . ILE A 1 429 ? 110.223 106.000 117.933 1.00 66.93  ? 420 ILE A HB     1 
ATOM   5004 H HG12   . ILE A 1 429 ? 111.546 105.638 119.831 1.00 66.93  ? 420 ILE A HG12   1 
ATOM   5005 H HG13   . ILE A 1 429 ? 112.455 105.724 118.535 1.00 66.93  ? 420 ILE A HG13   1 
ATOM   5006 H HG21   . ILE A 1 429 ? 110.458 107.717 116.531 1.00 66.93  ? 420 ILE A HG21   1 
ATOM   5007 H HG22   . ILE A 1 429 ? 111.311 108.557 117.576 1.00 66.93  ? 420 ILE A HG22   1 
ATOM   5008 H HG23   . ILE A 1 429 ? 111.964 107.316 116.829 1.00 66.93  ? 420 ILE A HG23   1 
ATOM   5009 H HD11   . ILE A 1 429 ? 113.520 106.888 120.162 1.00 66.93  ? 420 ILE A HD11   1 
ATOM   5010 H HD12   . ILE A 1 429 ? 112.211 107.713 120.509 1.00 66.93  ? 420 ILE A HD12   1 
ATOM   5011 H HD13   . ILE A 1 429 ? 112.971 107.965 119.136 1.00 66.93  ? 420 ILE A HD13   1 
ATOM   5012 N N      . GLY A 1 430 ? 107.577 107.554 118.053 1.00 66.66  ? 421 GLY A N      1 
ATOM   5013 C CA     . GLY A 1 430 ? 106.524 108.232 117.315 1.00 66.66  ? 421 GLY A CA     1 
ATOM   5014 C C      . GLY A 1 430 ? 105.893 109.352 118.118 1.00 66.66  ? 421 GLY A C      1 
ATOM   5015 O O      . GLY A 1 430 ? 105.757 110.481 117.637 1.00 66.66  ? 421 GLY A O      1 
ATOM   5016 H H      . GLY A 1 430 ? 107.446 106.715 118.186 1.00 66.66  ? 421 GLY A H      1 
ATOM   5017 H HA2    . GLY A 1 430 ? 106.891 108.606 116.499 1.00 66.66  ? 421 GLY A HA2    1 
ATOM   5018 H HA3    . GLY A 1 430 ? 105.831 107.596 117.080 1.00 66.66  ? 421 GLY A HA3    1 
ATOM   5019 N N      . PHE A 1 431 ? 105.518 109.060 119.365 1.00 65.28  ? 422 PHE A N      1 
ATOM   5020 C CA     . PHE A 1 431 ? 104.929 110.092 120.210 1.00 65.28  ? 422 PHE A CA     1 
ATOM   5021 C C      . PHE A 1 431 ? 105.922 111.215 120.476 1.00 65.28  ? 422 PHE A C      1 
ATOM   5022 O O      . PHE A 1 431 ? 105.551 112.398 120.478 1.00 65.28  ? 422 PHE A O      1 
ATOM   5023 C CB     . PHE A 1 431 ? 104.447 109.485 121.529 1.00 65.28  ? 422 PHE A CB     1 
ATOM   5024 C CG     . PHE A 1 431 ? 103.126 108.767 121.434 1.00 65.28  ? 422 PHE A CG     1 
ATOM   5025 C CD1    . PHE A 1 431 ? 102.094 109.263 120.658 1.00 65.28  ? 422 PHE A CD1    1 
ATOM   5026 C CD2    . PHE A 1 431 ? 102.915 107.598 122.141 1.00 65.28  ? 422 PHE A CD2    1 
ATOM   5027 C CE1    . PHE A 1 431 ? 100.887 108.602 120.585 1.00 65.28  ? 422 PHE A CE1    1 
ATOM   5028 C CE2    . PHE A 1 431 ? 101.709 106.936 122.071 1.00 65.28  ? 422 PHE A CE2    1 
ATOM   5029 C CZ     . PHE A 1 431 ? 100.695 107.438 121.294 1.00 65.28  ? 422 PHE A CZ     1 
ATOM   5030 H H      . PHE A 1 431 ? 105.593 108.288 119.736 1.00 65.28  ? 422 PHE A H      1 
ATOM   5031 H HA     . PHE A 1 431 ? 104.176 110.485 119.745 1.00 65.28  ? 422 PHE A HA     1 
ATOM   5032 H HB2    . PHE A 1 431 ? 105.109 108.846 121.838 1.00 65.28  ? 422 PHE A HB2    1 
ATOM   5033 H HB3    . PHE A 1 431 ? 104.351 110.196 122.181 1.00 65.28  ? 422 PHE A HB3    1 
ATOM   5034 H HD1    . PHE A 1 431 ? 102.215 110.050 120.178 1.00 65.28  ? 422 PHE A HD1    1 
ATOM   5035 H HD2    . PHE A 1 431 ? 103.598 107.253 122.670 1.00 65.28  ? 422 PHE A HD2    1 
ATOM   5036 H HE1    . PHE A 1 431 ? 100.200 108.943 120.059 1.00 65.28  ? 422 PHE A HE1    1 
ATOM   5037 H HE2    . PHE A 1 431 ? 101.582 106.149 122.549 1.00 65.28  ? 422 PHE A HE2    1 
ATOM   5038 H HZ     . PHE A 1 431 ? 99.881  106.990 121.244 1.00 65.28  ? 422 PHE A HZ     1 
ATOM   5039 N N      . LEU A 1 432 ? 107.187 110.869 120.715 1.00 64.25  ? 423 LEU A N      1 
ATOM   5040 C CA     . LEU A 1 432 ? 108.180 111.893 121.010 1.00 64.25  ? 423 LEU A CA     1 
ATOM   5041 C C      . LEU A 1 432 ? 108.335 112.853 119.839 1.00 64.25  ? 423 LEU A C      1 
ATOM   5042 O O      . LEU A 1 432 ? 108.369 114.074 120.023 1.00 64.25  ? 423 LEU A O      1 
ATOM   5043 C CB     . LEU A 1 432 ? 109.517 111.243 121.356 1.00 64.25  ? 423 LEU A CB     1 
ATOM   5044 C CG     . LEU A 1 432 ? 110.649 112.220 121.672 1.00 64.25  ? 423 LEU A CG     1 
ATOM   5045 C CD1    . LEU A 1 432 ? 110.286 113.096 122.855 1.00 64.25  ? 423 LEU A CD1    1 
ATOM   5046 C CD2    . LEU A 1 432 ? 111.934 111.464 121.937 1.00 64.25  ? 423 LEU A CD2    1 
ATOM   5047 H H      . LEU A 1 432 ? 107.489 110.064 120.713 1.00 64.25  ? 423 LEU A H      1 
ATOM   5048 H HA     . LEU A 1 432 ? 107.883 112.404 121.780 1.00 64.25  ? 423 LEU A HA     1 
ATOM   5049 H HB2    . LEU A 1 432 ? 109.393 110.677 122.134 1.00 64.25  ? 423 LEU A HB2    1 
ATOM   5050 H HB3    . LEU A 1 432 ? 109.801 110.701 120.602 1.00 64.25  ? 423 LEU A HB3    1 
ATOM   5051 H HG     . LEU A 1 432 ? 110.796 112.796 120.906 1.00 64.25  ? 423 LEU A HG     1 
ATOM   5052 H HD11   . LEU A 1 432 ? 111.069 113.602 123.123 1.00 64.25  ? 423 LEU A HD11   1 
ATOM   5053 H HD12   . LEU A 1 432 ? 109.575 113.702 122.595 1.00 64.25  ? 423 LEU A HD12   1 
ATOM   5054 H HD13   . LEU A 1 432 ? 109.990 112.532 123.586 1.00 64.25  ? 423 LEU A HD13   1 
ATOM   5055 H HD21   . LEU A 1 432 ? 111.794 110.856 122.679 1.00 64.25  ? 423 LEU A HD21   1 
ATOM   5056 H HD22   . LEU A 1 432 ? 112.634 112.099 122.156 1.00 64.25  ? 423 LEU A HD22   1 
ATOM   5057 H HD23   . LEU A 1 432 ? 112.177 110.966 121.141 1.00 64.25  ? 423 LEU A HD23   1 
ATOM   5058 N N      . LEU A 1 433 ? 108.420 112.321 118.618 1.00 63.30  ? 424 LEU A N      1 
ATOM   5059 C CA     . LEU A 1 433 ? 108.542 113.195 117.456 1.00 63.30  ? 424 LEU A CA     1 
ATOM   5060 C C      . LEU A 1 433 ? 107.261 113.981 117.210 1.00 63.30  ? 424 LEU A C      1 
ATOM   5061 O O      . LEU A 1 433 ? 107.319 115.146 116.794 1.00 63.30  ? 424 LEU A O      1 
ATOM   5062 C CB     . LEU A 1 433 ? 108.918 112.380 116.221 1.00 63.30  ? 424 LEU A CB     1 
ATOM   5063 C CG     . LEU A 1 433 ? 110.270 111.668 116.302 1.00 63.30  ? 424 LEU A CG     1 
ATOM   5064 C CD1    . LEU A 1 433 ? 110.562 110.927 115.009 1.00 63.30  ? 424 LEU A CD1    1 
ATOM   5065 C CD2    . LEU A 1 433 ? 111.389 112.648 116.623 1.00 63.30  ? 424 LEU A CD2    1 
ATOM   5066 H H      . LEU A 1 433 ? 108.408 111.479 118.440 1.00 63.30  ? 424 LEU A H      1 
ATOM   5067 H HA     . LEU A 1 433 ? 109.249 113.838 117.622 1.00 63.30  ? 424 LEU A HA     1 
ATOM   5068 H HB2    . LEU A 1 433 ? 108.238 111.702 116.081 1.00 63.30  ? 424 LEU A HB2    1 
ATOM   5069 H HB3    . LEU A 1 433 ? 108.946 112.975 115.455 1.00 63.30  ? 424 LEU A HB3    1 
ATOM   5070 H HG     . LEU A 1 433 ? 110.237 111.014 117.018 1.00 63.30  ? 424 LEU A HG     1 
ATOM   5071 H HD11   . LEU A 1 433 ? 111.423 110.486 115.086 1.00 63.30  ? 424 LEU A HD11   1 
ATOM   5072 H HD12   . LEU A 1 433 ? 109.866 110.269 114.859 1.00 63.30  ? 424 LEU A HD12   1 
ATOM   5073 H HD13   . LEU A 1 433 ? 110.581 111.564 114.278 1.00 63.30  ? 424 LEU A HD13   1 
ATOM   5074 H HD21   . LEU A 1 433 ? 111.306 113.421 116.043 1.00 63.30  ? 424 LEU A HD21   1 
ATOM   5075 H HD22   . LEU A 1 433 ? 112.242 112.212 116.474 1.00 63.30  ? 424 LEU A HD22   1 
ATOM   5076 H HD23   . LEU A 1 433 ? 111.315 112.921 117.551 1.00 63.30  ? 424 LEU A HD23   1 
ATOM   5077 N N      . GLY A 1 434 ? 106.100 113.378 117.469 1.00 64.21  ? 425 GLY A N      1 
ATOM   5078 C CA     . GLY A 1 434 ? 104.863 114.133 117.359 1.00 64.21  ? 425 GLY A CA     1 
ATOM   5079 C C      . GLY A 1 434 ? 104.863 115.358 118.253 1.00 64.21  ? 425 GLY A C      1 
ATOM   5080 O O      . GLY A 1 434 ? 104.510 116.459 117.824 1.00 64.21  ? 425 GLY A O      1 
ATOM   5081 H H      . GLY A 1 434 ? 106.006 112.556 117.703 1.00 64.21  ? 425 GLY A H      1 
ATOM   5082 H HA2    . GLY A 1 434 ? 104.740 114.421 116.440 1.00 64.21  ? 425 GLY A HA2    1 
ATOM   5083 H HA3    . GLY A 1 434 ? 104.115 113.569 117.610 1.00 64.21  ? 425 GLY A HA3    1 
ATOM   5084 N N      . PHE A 1 435 ? 105.272 115.184 119.512 1.00 63.52  ? 426 PHE A N      1 
ATOM   5085 C CA     . PHE A 1 435 ? 105.381 116.334 120.404 1.00 63.52  ? 426 PHE A CA     1 
ATOM   5086 C C      . PHE A 1 435 ? 106.450 117.305 119.921 1.00 63.52  ? 426 PHE A C      1 
ATOM   5087 O O      . PHE A 1 435 ? 106.259 118.524 119.974 1.00 63.52  ? 426 PHE A O      1 
ATOM   5088 C CB     . PHE A 1 435 ? 105.690 115.880 121.831 1.00 63.52  ? 426 PHE A CB     1 
ATOM   5089 C CG     . PHE A 1 435 ? 104.539 115.203 122.528 1.00 63.52  ? 426 PHE A CG     1 
ATOM   5090 C CD1    . PHE A 1 435 ? 103.232 115.407 122.123 1.00 63.52  ? 426 PHE A CD1    1 
ATOM   5091 C CD2    . PHE A 1 435 ? 104.774 114.363 123.601 1.00 63.52  ? 426 PHE A CD2    1 
ATOM   5092 C CE1    . PHE A 1 435 ? 102.188 114.782 122.772 1.00 63.52  ? 426 PHE A CE1    1 
ATOM   5093 C CE2    . PHE A 1 435 ? 103.732 113.736 124.252 1.00 63.52  ? 426 PHE A CE2    1 
ATOM   5094 C CZ     . PHE A 1 435 ? 102.439 113.947 123.837 1.00 63.52  ? 426 PHE A CZ     1 
ATOM   5095 H H      . PHE A 1 435 ? 105.485 114.429 119.865 1.00 63.52  ? 426 PHE A H      1 
ATOM   5096 H HA     . PHE A 1 435 ? 104.544 116.821 120.401 1.00 63.52  ? 426 PHE A HA     1 
ATOM   5097 H HB2    . PHE A 1 435 ? 106.429 115.252 121.805 1.00 63.52  ? 426 PHE A HB2    1 
ATOM   5098 H HB3    . PHE A 1 435 ? 105.938 116.655 122.358 1.00 63.52  ? 426 PHE A HB3    1 
ATOM   5099 H HD1    . PHE A 1 435 ? 103.050 115.968 121.406 1.00 63.52  ? 426 PHE A HD1    1 
ATOM   5100 H HD2    . PHE A 1 435 ? 105.647 114.215 123.886 1.00 63.52  ? 426 PHE A HD2    1 
ATOM   5101 H HE1    . PHE A 1 435 ? 101.314 114.926 122.490 1.00 63.52  ? 426 PHE A HE1    1 
ATOM   5102 H HE2    . PHE A 1 435 ? 103.904 113.173 124.971 1.00 63.52  ? 426 PHE A HE2    1 
ATOM   5103 H HZ     . PHE A 1 435 ? 101.735 113.526 124.274 1.00 63.52  ? 426 PHE A HZ     1 
ATOM   5104 N N      . MET A 1 436 ? 107.584 116.785 119.448 1.00 62.93  ? 427 MET A N      1 
ATOM   5105 C CA     . MET A 1 436 ? 108.679 117.643 119.011 1.00 62.93  ? 427 MET A CA     1 
ATOM   5106 C C      . MET A 1 436 ? 108.327 118.452 117.773 1.00 62.93  ? 427 MET A C      1 
ATOM   5107 O O      . MET A 1 436 ? 109.037 119.409 117.450 1.00 62.93  ? 427 MET A O      1 
ATOM   5108 C CB     . MET A 1 436 ? 109.920 116.799 118.728 1.00 62.93  ? 427 MET A CB     1 
ATOM   5109 C CG     . MET A 1 436 ? 110.446 116.053 119.935 1.00 62.93  ? 427 MET A CG     1 
ATOM   5110 S SD     . MET A 1 436 ? 111.945 116.790 120.599 1.00 62.93  ? 427 MET A SD     1 
ATOM   5111 C CE     . MET A 1 436 ? 113.106 116.419 119.291 1.00 62.93  ? 427 MET A CE     1 
ATOM   5112 H H      . MET A 1 436 ? 107.741 115.943 119.373 1.00 62.93  ? 427 MET A H      1 
ATOM   5113 H HA     . MET A 1 436 ? 108.898 118.256 119.730 1.00 62.93  ? 427 MET A HA     1 
ATOM   5114 H HB2    . MET A 1 436 ? 109.701 116.143 118.047 1.00 62.93  ? 427 MET A HB2    1 
ATOM   5115 H HB3    . MET A 1 436 ? 110.626 117.382 118.407 1.00 62.93  ? 427 MET A HB3    1 
ATOM   5116 H HG2    . MET A 1 436 ? 109.773 116.062 120.634 1.00 62.93  ? 427 MET A HG2    1 
ATOM   5117 H HG3    . MET A 1 436 ? 110.649 115.140 119.679 1.00 62.93  ? 427 MET A HG3    1 
ATOM   5118 H HE1    . MET A 1 436 ? 112.864 116.924 118.499 1.00 62.93  ? 427 MET A HE1    1 
ATOM   5119 H HE2    . MET A 1 436 ? 113.998 116.665 119.582 1.00 62.93  ? 427 MET A HE2    1 
ATOM   5120 H HE3    . MET A 1 436 ? 113.073 115.468 119.101 1.00 62.93  ? 427 MET A HE3    1 
ATOM   5121 N N      . SER A 1 437 ? 107.266 118.075 117.061 1.00 60.45  ? 428 SER A N      1 
ATOM   5122 C CA     . SER A 1 437 ? 106.885 118.821 115.865 1.00 60.45  ? 428 SER A CA     1 
ATOM   5123 C C      . SER A 1 437 ? 106.643 120.298 116.165 1.00 60.45  ? 428 SER A C      1 
ATOM   5124 O O      . SER A 1 437 ? 106.937 121.160 115.330 1.00 60.45  ? 428 SER A O      1 
ATOM   5125 C CB     . SER A 1 437 ? 105.636 118.204 115.244 1.00 60.45  ? 428 SER A CB     1 
ATOM   5126 O OG     . SER A 1 437 ? 105.124 119.033 114.218 1.00 60.45  ? 428 SER A OG     1 
ATOM   5127 H H      . SER A 1 437 ? 106.761 117.404 117.243 1.00 60.45  ? 428 SER A H      1 
ATOM   5128 H HA     . SER A 1 437 ? 107.603 118.763 115.216 1.00 60.45  ? 428 SER A HA     1 
ATOM   5129 H HB2    . SER A 1 437 ? 105.864 117.340 114.867 1.00 60.45  ? 428 SER A HB2    1 
ATOM   5130 H HB3    . SER A 1 437 ? 104.960 118.097 115.932 1.00 60.45  ? 428 SER A HB3    1 
ATOM   5131 H HG     . SER A 1 437 ? 105.703 119.140 113.619 1.00 60.45  ? 428 SER A HG     1 
ATOM   5132 N N      . ILE A 1 438 ? 106.102 120.612 117.340 1.00 59.26  ? 429 ILE A N      1 
ATOM   5133 C CA     . ILE A 1 438 ? 105.608 121.960 117.633 1.00 59.26  ? 429 ILE A CA     1 
ATOM   5134 C C      . ILE A 1 438 ? 106.741 122.926 117.965 1.00 59.26  ? 429 ILE A C      1 
ATOM   5135 O O      . ILE A 1 438 ? 106.838 123.991 117.334 1.00 59.26  ? 429 ILE A O      1 
ATOM   5136 C CB     . ILE A 1 438 ? 104.576 121.929 118.773 1.00 59.26  ? 429 ILE A CB     1 
ATOM   5137 C CG1    . ILE A 1 438 ? 103.192 121.572 118.230 1.00 59.26  ? 429 ILE A CG1    1 
ATOM   5138 C CG2    . ILE A 1 438 ? 104.521 123.265 119.498 1.00 59.26  ? 429 ILE A CG2    1 
ATOM   5139 C CD1    . ILE A 1 438 ? 102.512 122.696 117.469 1.00 59.26  ? 429 ILE A CD1    1 
ATOM   5140 H H      . ILE A 1 438 ? 106.007 120.059 117.991 1.00 59.26  ? 429 ILE A H      1 
ATOM   5141 H HA     . ILE A 1 438 ? 105.165 122.299 116.840 1.00 59.26  ? 429 ILE A HA     1 
ATOM   5142 H HB     . ILE A 1 438 ? 104.831 121.243 119.408 1.00 59.26  ? 429 ILE A HB     1 
ATOM   5143 H HG12   . ILE A 1 438 ? 103.279 120.817 117.628 1.00 59.26  ? 429 ILE A HG12   1 
ATOM   5144 H HG13   . ILE A 1 438 ? 102.618 121.332 118.975 1.00 59.26  ? 429 ILE A HG13   1 
ATOM   5145 H HG21   . ILE A 1 438 ? 105.289 123.347 120.085 1.00 59.26  ? 429 ILE A HG21   1 
ATOM   5146 H HG22   . ILE A 1 438 ? 103.707 123.296 120.025 1.00 59.26  ? 429 ILE A HG22   1 
ATOM   5147 H HG23   . ILE A 1 438 ? 104.514 123.986 118.848 1.00 59.26  ? 429 ILE A HG23   1 
ATOM   5148 H HD11   . ILE A 1 438 ? 101.737 122.337 117.009 1.00 59.26  ? 429 ILE A HD11   1 
ATOM   5149 H HD12   . ILE A 1 438 ? 102.232 123.382 118.095 1.00 59.26  ? 429 ILE A HD12   1 
ATOM   5150 H HD13   . ILE A 1 438 ? 103.132 123.070 116.824 1.00 59.26  ? 429 ILE A HD13   1 
ATOM   5151 N N      . PRO A 1 439 ? 107.603 122.624 118.939 1.00 59.66  ? 430 PRO A N      1 
ATOM   5152 C CA     . PRO A 1 439 ? 108.574 123.638 119.386 1.00 59.66  ? 430 PRO A CA     1 
ATOM   5153 C C      . PRO A 1 439 ? 109.438 124.205 118.273 1.00 59.66  ? 430 PRO A C      1 
ATOM   5154 O O      . PRO A 1 439 ? 109.695 125.416 118.256 1.00 59.66  ? 430 PRO A O      1 
ATOM   5155 C CB     . PRO A 1 439 ? 109.414 122.876 120.418 1.00 59.66  ? 430 PRO A CB     1 
ATOM   5156 C CG     . PRO A 1 439 ? 108.532 121.797 120.898 1.00 59.66  ? 430 PRO A CG     1 
ATOM   5157 C CD     . PRO A 1 439 ? 107.715 121.383 119.721 1.00 59.66  ? 430 PRO A CD     1 
ATOM   5158 H HA     . PRO A 1 439 ? 108.113 124.367 119.830 1.00 59.66  ? 430 PRO A HA     1 
ATOM   5159 H HB2    . PRO A 1 439 ? 110.205 122.511 119.992 1.00 59.66  ? 430 PRO A HB2    1 
ATOM   5160 H HB3    . PRO A 1 439 ? 109.656 123.470 121.146 1.00 59.66  ? 430 PRO A HB3    1 
ATOM   5161 H HG2    . PRO A 1 439 ? 109.071 121.055 121.215 1.00 59.66  ? 430 PRO A HG2    1 
ATOM   5162 H HG3    . PRO A 1 439 ? 107.963 122.133 121.608 1.00 59.66  ? 430 PRO A HG3    1 
ATOM   5163 H HD2    . PRO A 1 439 ? 108.182 120.705 119.214 1.00 59.66  ? 430 PRO A HD2    1 
ATOM   5164 H HD3    . PRO A 1 439 ? 106.846 121.074 120.013 1.00 59.66  ? 430 PRO A HD3    1 
ATOM   5165 N N      . MET A 1 440 ? 109.893 123.372 117.337 1.00 60.32  ? 431 MET A N      1 
ATOM   5166 C CA     . MET A 1 440 ? 110.745 123.875 116.268 1.00 60.32  ? 431 MET A CA     1 
ATOM   5167 C C      . MET A 1 440 ? 109.969 124.712 115.263 1.00 60.32  ? 431 MET A C      1 
ATOM   5168 O O      . MET A 1 440 ? 110.566 125.559 114.592 1.00 60.32  ? 431 MET A O      1 
ATOM   5169 C CB     . MET A 1 440 ? 111.437 122.714 115.560 1.00 60.32  ? 431 MET A CB     1 
ATOM   5170 C CG     . MET A 1 440 ? 112.299 121.879 116.488 1.00 60.32  ? 431 MET A CG     1 
ATOM   5171 S SD     . MET A 1 440 ? 113.329 120.688 115.620 1.00 60.32  ? 431 MET A SD     1 
ATOM   5172 C CE     . MET A 1 440 ? 114.514 121.773 114.834 1.00 60.32  ? 431 MET A CE     1 
ATOM   5173 H H      . MET A 1 440 ? 109.725 122.529 117.300 1.00 60.32  ? 431 MET A H      1 
ATOM   5174 H HA     . MET A 1 440 ? 111.436 124.430 116.662 1.00 60.32  ? 431 MET A HA     1 
ATOM   5175 H HB2    . MET A 1 440 ? 110.762 122.133 115.175 1.00 60.32  ? 431 MET A HB2    1 
ATOM   5176 H HB3    . MET A 1 440 ? 112.003 123.071 114.860 1.00 60.32  ? 431 MET A HB3    1 
ATOM   5177 H HG2    . MET A 1 440 ? 112.883 122.469 116.989 1.00 60.32  ? 431 MET A HG2    1 
ATOM   5178 H HG3    . MET A 1 440 ? 111.723 121.388 117.095 1.00 60.32  ? 431 MET A HG3    1 
ATOM   5179 H HE1    . MET A 1 440 ? 115.085 121.246 114.254 1.00 60.32  ? 431 MET A HE1    1 
ATOM   5180 H HE2    . MET A 1 440 ? 114.041 122.441 114.315 1.00 60.32  ? 431 MET A HE2    1 
ATOM   5181 H HE3    . MET A 1 440 ? 115.048 122.203 115.520 1.00 60.32  ? 431 MET A HE3    1 
ATOM   5182 N N      . THR A 1 441 ? 108.660 124.496 115.141 1.00 59.86  ? 432 THR A N      1 
ATOM   5183 C CA     . THR A 1 441 ? 107.845 125.361 114.296 1.00 59.86  ? 432 THR A CA     1 
ATOM   5184 C C      . THR A 1 441 ? 107.570 126.696 114.971 1.00 59.86  ? 432 THR A C      1 
ATOM   5185 O O      . THR A 1 441 ? 107.492 127.729 114.300 1.00 59.86  ? 432 THR A O      1 
ATOM   5186 C CB     . THR A 1 441 ? 106.526 124.673 113.951 1.00 59.86  ? 432 THR A CB     1 
ATOM   5187 O OG1    . THR A 1 441 ? 106.782 123.518 113.144 1.00 59.86  ? 432 THR A OG1    1 
ATOM   5188 C CG2    . THR A 1 441 ? 105.606 125.624 113.202 1.00 59.86  ? 432 THR A CG2    1 
ATOM   5189 H H      . THR A 1 441 ? 108.226 123.865 115.531 1.00 59.86  ? 432 THR A H      1 
ATOM   5190 H HA     . THR A 1 441 ? 108.320 125.535 113.469 1.00 59.86  ? 432 THR A HA     1 
ATOM   5191 H HB     . THR A 1 441 ? 106.083 124.401 114.770 1.00 59.86  ? 432 THR A HB     1 
ATOM   5192 H HG1    . THR A 1 441 ? 107.259 122.973 113.569 1.00 59.86  ? 432 THR A HG1    1 
ATOM   5193 H HG21   . THR A 1 441 ? 104.918 125.121 112.739 1.00 59.86  ? 432 THR A HG21   1 
ATOM   5194 H HG22   . THR A 1 441 ? 105.182 126.238 113.821 1.00 59.86  ? 432 THR A HG22   1 
ATOM   5195 H HG23   . THR A 1 441 ? 106.114 126.131 112.549 1.00 59.86  ? 432 THR A HG23   1 
ATOM   5196 N N      . VAL A 1 442 ? 107.413 126.694 116.295 1.00 58.85  ? 433 VAL A N      1 
ATOM   5197 C CA     . VAL A 1 442 ? 107.061 127.919 117.004 1.00 58.85  ? 433 VAL A CA     1 
ATOM   5198 C C      . VAL A 1 442 ? 108.272 128.758 117.396 1.00 58.85  ? 433 VAL A C      1 
ATOM   5199 O O      . VAL A 1 442 ? 108.114 129.950 117.695 1.00 58.85  ? 433 VAL A O      1 
ATOM   5200 C CB     . VAL A 1 442 ? 106.232 127.591 118.258 1.00 58.85  ? 433 VAL A CB     1 
ATOM   5201 C CG1    . VAL A 1 442 ? 106.063 128.819 119.130 1.00 58.85  ? 433 VAL A CG1    1 
ATOM   5202 C CG2    . VAL A 1 442 ? 104.877 127.043 117.859 1.00 58.85  ? 433 VAL A CG2    1 
ATOM   5203 H H      . VAL A 1 442 ? 107.504 126.003 116.799 1.00 58.85  ? 433 VAL A H      1 
ATOM   5204 H HA     . VAL A 1 442 ? 106.507 128.462 116.422 1.00 58.85  ? 433 VAL A HA     1 
ATOM   5205 H HB     . VAL A 1 442 ? 106.693 126.913 118.777 1.00 58.85  ? 433 VAL A HB     1 
ATOM   5206 H HG11   . VAL A 1 442 ? 106.875 128.967 119.640 1.00 58.85  ? 433 VAL A HG11   1 
ATOM   5207 H HG12   . VAL A 1 442 ? 105.319 128.672 119.735 1.00 58.85  ? 433 VAL A HG12   1 
ATOM   5208 H HG13   . VAL A 1 442 ? 105.877 129.584 118.563 1.00 58.85  ? 433 VAL A HG13   1 
ATOM   5209 H HG21   . VAL A 1 442 ? 104.374 126.829 118.661 1.00 58.85  ? 433 VAL A HG21   1 
ATOM   5210 H HG22   . VAL A 1 442 ? 104.405 127.714 117.341 1.00 58.85  ? 433 VAL A HG22   1 
ATOM   5211 H HG23   . VAL A 1 442 ? 105.005 126.243 117.326 1.00 58.85  ? 433 VAL A HG23   1 
ATOM   5212 N N      . GLY A 1 443 ? 109.472 128.186 117.396 1.00 59.14  ? 434 GLY A N      1 
ATOM   5213 C CA     . GLY A 1 443 ? 110.634 128.908 117.857 1.00 59.14  ? 434 GLY A CA     1 
ATOM   5214 C C      . GLY A 1 443 ? 111.011 130.109 117.010 1.00 59.14  ? 434 GLY A C      1 
ATOM   5215 O O      . GLY A 1 443 ? 110.868 131.259 117.436 1.00 59.14  ? 434 GLY A O      1 
ATOM   5216 H H      . GLY A 1 443 ? 109.631 127.383 117.136 1.00 59.14  ? 434 GLY A H      1 
ATOM   5217 H HA2    . GLY A 1 443 ? 110.472 129.217 118.762 1.00 59.14  ? 434 GLY A HA2    1 
ATOM   5218 H HA3    . GLY A 1 443 ? 111.392 128.304 117.880 1.00 59.14  ? 434 GLY A HA3    1 
ATOM   5219 N N      . PRO A 1 444 ? 111.490 129.867 115.793 1.00 60.43  ? 435 PRO A N      1 
ATOM   5220 C CA     . PRO A 1 444 ? 112.127 130.937 115.009 1.00 60.43  ? 435 PRO A CA     1 
ATOM   5221 C C      . PRO A 1 444 ? 111.211 132.129 114.789 1.00 60.43  ? 435 PRO A C      1 
ATOM   5222 O O      . PRO A 1 444 ? 111.667 133.280 114.862 1.00 60.43  ? 435 PRO A O      1 
ATOM   5223 C CB     . PRO A 1 444 ? 112.472 130.244 113.684 1.00 60.43  ? 435 PRO A CB     1 
ATOM   5224 C CG     . PRO A 1 444 ? 112.596 128.814 114.035 1.00 60.43  ? 435 PRO A CG     1 
ATOM   5225 C CD     . PRO A 1 444 ? 111.602 128.560 115.126 1.00 60.43  ? 435 PRO A CD     1 
ATOM   5226 H HA     . PRO A 1 444 ? 112.944 131.233 115.442 1.00 60.43  ? 435 PRO A HA     1 
ATOM   5227 H HB2    . PRO A 1 444 ? 111.765 130.386 113.038 1.00 60.43  ? 435 PRO A HB2    1 
ATOM   5228 H HB3    . PRO A 1 444 ? 113.315 130.587 113.349 1.00 60.43  ? 435 PRO A HB3    1 
ATOM   5229 H HG2    . PRO A 1 444 ? 112.392 128.272 113.257 1.00 60.43  ? 435 PRO A HG2    1 
ATOM   5230 H HG3    . PRO A 1 444 ? 113.497 128.635 114.348 1.00 60.43  ? 435 PRO A HG3    1 
ATOM   5231 H HD2    . PRO A 1 444 ? 110.747 128.294 114.751 1.00 60.43  ? 435 PRO A HD2    1 
ATOM   5232 H HD3    . PRO A 1 444 ? 111.945 127.891 115.738 1.00 60.43  ? 435 PRO A HD3    1 
ATOM   5233 N N      . PRO A 1 445 ? 109.923 131.919 114.501 1.00 60.14  ? 436 PRO A N      1 
ATOM   5234 C CA     . PRO A 1 445 ? 109.053 133.090 114.284 1.00 60.14  ? 436 PRO A CA     1 
ATOM   5235 C C      . PRO A 1 445 ? 108.939 133.973 115.511 1.00 60.14  ? 436 PRO A C      1 
ATOM   5236 O O      . PRO A 1 445 ? 109.101 135.200 115.419 1.00 60.14  ? 436 PRO A O      1 
ATOM   5237 C CB     . PRO A 1 445 ? 107.707 132.459 113.899 1.00 60.14  ? 436 PRO A CB     1 
ATOM   5238 C CG     . PRO A 1 445 ? 108.040 131.102 113.417 1.00 60.14  ? 436 PRO A CG     1 
ATOM   5239 C CD     . PRO A 1 445 ? 109.208 130.660 114.236 1.00 60.14  ? 436 PRO A CD     1 
ATOM   5240 H HA     . PRO A 1 445 ? 109.381 133.618 113.540 1.00 60.14  ? 436 PRO A HA     1 
ATOM   5241 H HB2    . PRO A 1 445 ? 107.133 132.414 114.679 1.00 60.14  ? 436 PRO A HB2    1 
ATOM   5242 H HB3    . PRO A 1 445 ? 107.290 132.980 113.196 1.00 60.14  ? 436 PRO A HB3    1 
ATOM   5243 H HG2    . PRO A 1 445 ? 107.283 130.512 113.555 1.00 60.14  ? 436 PRO A HG2    1 
ATOM   5244 H HG3    . PRO A 1 445 ? 108.278 131.140 112.477 1.00 60.14  ? 436 PRO A HG3    1 
ATOM   5245 H HD2    . PRO A 1 445 ? 108.905 130.261 115.066 1.00 60.14  ? 436 PRO A HD2    1 
ATOM   5246 H HD3    . PRO A 1 445 ? 109.758 130.048 113.726 1.00 60.14  ? 436 PRO A HD3    1 
ATOM   5247 N N      . ILE A 1 446 ? 108.657 133.375 116.669 1.00 62.50  ? 437 ILE A N      1 
ATOM   5248 C CA     . ILE A 1 446 ? 108.562 134.149 117.900 1.00 62.50  ? 437 ILE A CA     1 
ATOM   5249 C C      . ILE A 1 446 ? 109.894 134.813 118.210 1.00 62.50  ? 437 ILE A C      1 
ATOM   5250 O O      . ILE A 1 446 ? 109.939 135.962 118.657 1.00 62.50  ? 437 ILE A O      1 
ATOM   5251 C CB     . ILE A 1 446 ? 108.090 133.254 119.060 1.00 62.50  ? 437 ILE A CB     1 
ATOM   5252 C CG1    . ILE A 1 446 ? 106.616 132.894 118.867 1.00 62.50  ? 437 ILE A CG1    1 
ATOM   5253 C CG2    . ILE A 1 446 ? 108.324 133.951 120.394 1.00 62.50  ? 437 ILE A CG2    1 
ATOM   5254 C CD1    . ILE A 1 446 ? 106.064 131.957 119.916 1.00 62.50  ? 437 ILE A CD1    1 
ATOM   5255 H H      . ILE A 1 446 ? 108.519 132.531 116.765 1.00 62.50  ? 437 ILE A H      1 
ATOM   5256 H HA     . ILE A 1 446 ? 107.902 134.850 117.779 1.00 62.50  ? 437 ILE A HA     1 
ATOM   5257 H HB     . ILE A 1 446 ? 108.610 132.435 119.046 1.00 62.50  ? 437 ILE A HB     1 
ATOM   5258 H HG12   . ILE A 1 446 ? 106.091 133.709 118.894 1.00 62.50  ? 437 ILE A HG12   1 
ATOM   5259 H HG13   . ILE A 1 446 ? 106.510 132.465 118.004 1.00 62.50  ? 437 ILE A HG13   1 
ATOM   5260 H HG21   . ILE A 1 446 ? 107.820 133.501 121.089 1.00 62.50  ? 437 ILE A HG21   1 
ATOM   5261 H HG22   . ILE A 1 446 ? 108.034 134.873 120.322 1.00 62.50  ? 437 ILE A HG22   1 
ATOM   5262 H HG23   . ILE A 1 446 ? 109.270 133.919 120.608 1.00 62.50  ? 437 ILE A HG23   1 
ATOM   5263 H HD11   . ILE A 1 446 ? 105.255 131.545 119.575 1.00 62.50  ? 437 ILE A HD11   1 
ATOM   5264 H HD12   . ILE A 1 446 ? 105.864 132.463 120.719 1.00 62.50  ? 437 ILE A HD12   1 
ATOM   5265 H HD13   . ILE A 1 446 ? 106.727 131.276 120.109 1.00 62.50  ? 437 ILE A HD13   1 
ATOM   5266 N N      . ALA A 1 447 ? 111.000 134.100 117.992 1.00 63.80  ? 438 ALA A N      1 
ATOM   5267 C CA     . ALA A 1 447 ? 112.307 134.689 118.254 1.00 63.80  ? 438 ALA A CA     1 
ATOM   5268 C C      . ALA A 1 447 ? 112.529 135.923 117.392 1.00 63.80  ? 438 ALA A C      1 
ATOM   5269 O O      . ALA A 1 447 ? 113.023 136.948 117.875 1.00 63.80  ? 438 ALA A O      1 
ATOM   5270 C CB     . ALA A 1 447 ? 113.408 133.660 118.010 1.00 63.80  ? 438 ALA A CB     1 
ATOM   5271 H H      . ALA A 1 447 ? 111.019 133.291 117.700 1.00 63.80  ? 438 ALA A H      1 
ATOM   5272 H HA     . ALA A 1 447 ? 112.351 134.960 119.185 1.00 63.80  ? 438 ALA A HA     1 
ATOM   5273 H HB1    . ALA A 1 447 ? 113.269 132.906 118.603 1.00 63.80  ? 438 ALA A HB1    1 
ATOM   5274 H HB2    . ALA A 1 447 ? 114.269 134.070 118.190 1.00 63.80  ? 438 ALA A HB2    1 
ATOM   5275 H HB3    . ALA A 1 447 ? 113.367 133.367 117.086 1.00 63.80  ? 438 ALA A HB3    1 
ATOM   5276 N N      . GLY A 1 448 ? 112.165 135.846 116.113 1.00 61.39  ? 439 GLY A N      1 
ATOM   5277 C CA     . GLY A 1 448 ? 112.313 137.005 115.250 1.00 61.39  ? 439 GLY A CA     1 
ATOM   5278 C C      . GLY A 1 448 ? 111.442 138.163 115.692 1.00 61.39  ? 439 GLY A C      1 
ATOM   5279 O O      . GLY A 1 448 ? 111.892 139.310 115.756 1.00 61.39  ? 439 GLY A O      1 
ATOM   5280 H H      . GLY A 1 448 ? 111.836 135.149 115.732 1.00 61.39  ? 439 GLY A H      1 
ATOM   5281 H HA2    . GLY A 1 448 ? 113.238 137.297 115.256 1.00 61.39  ? 439 GLY A HA2    1 
ATOM   5282 H HA3    . GLY A 1 448 ? 112.072 136.766 114.342 1.00 61.39  ? 439 GLY A HA3    1 
ATOM   5283 N N      . LEU A 1 449 ? 110.181 137.876 116.013 1.00 65.31  ? 440 LEU A N      1 
ATOM   5284 C CA     . LEU A 1 449 ? 109.256 138.938 116.389 1.00 65.31  ? 440 LEU A CA     1 
ATOM   5285 C C      . LEU A 1 449 ? 109.539 139.500 117.776 1.00 65.31  ? 440 LEU A C      1 
ATOM   5286 O O      . LEU A 1 449 ? 109.060 140.594 118.092 1.00 65.31  ? 440 LEU A O      1 
ATOM   5287 C CB     . LEU A 1 449 ? 107.818 138.425 116.332 1.00 65.31  ? 440 LEU A CB     1 
ATOM   5288 C CG     . LEU A 1 449 ? 106.735 139.351 116.894 1.00 65.31  ? 440 LEU A CG     1 
ATOM   5289 C CD1    . LEU A 1 449 ? 106.717 140.675 116.152 1.00 65.31  ? 440 LEU A CD1    1 
ATOM   5290 C CD2    . LEU A 1 449 ? 105.376 138.682 116.822 1.00 65.31  ? 440 LEU A CD2    1 
ATOM   5291 H H      . LEU A 1 449 ? 109.842 137.086 116.020 1.00 65.31  ? 440 LEU A H      1 
ATOM   5292 H HA     . LEU A 1 449 ? 109.340 139.663 115.751 1.00 65.31  ? 440 LEU A HA     1 
ATOM   5293 H HB2    . LEU A 1 449 ? 107.594 138.254 115.404 1.00 65.31  ? 440 LEU A HB2    1 
ATOM   5294 H HB3    . LEU A 1 449 ? 107.772 137.593 116.830 1.00 65.31  ? 440 LEU A HB3    1 
ATOM   5295 H HG     . LEU A 1 449 ? 106.917 139.532 117.828 1.00 65.31  ? 440 LEU A HG     1 
ATOM   5296 H HD11   . LEU A 1 449 ? 107.580 141.108 116.250 1.00 65.31  ? 440 LEU A HD11   1 
ATOM   5297 H HD12   . LEU A 1 449 ? 106.021 141.237 116.527 1.00 65.31  ? 440 LEU A HD12   1 
ATOM   5298 H HD13   . LEU A 1 449 ? 106.536 140.507 115.214 1.00 65.31  ? 440 LEU A HD13   1 
ATOM   5299 H HD21   . LEU A 1 449 ? 105.180 138.463 115.897 1.00 65.31  ? 440 LEU A HD21   1 
ATOM   5300 H HD22   . LEU A 1 449 ? 104.706 139.293 117.166 1.00 65.31  ? 440 LEU A HD22   1 
ATOM   5301 H HD23   . LEU A 1 449 ? 105.392 137.874 117.358 1.00 65.31  ? 440 LEU A HD23   1 
ATOM   5302 N N      . LEU A 1 450 ? 110.312 138.789 118.602 1.00 64.72  ? 441 LEU A N      1 
ATOM   5303 C CA     . LEU A 1 450 ? 110.381 139.120 120.022 1.00 64.72  ? 441 LEU A CA     1 
ATOM   5304 C C      . LEU A 1 450 ? 110.789 140.567 120.257 1.00 64.72  ? 441 LEU A C      1 
ATOM   5305 O O      . LEU A 1 450 ? 110.285 141.204 121.188 1.00 64.72  ? 441 LEU A O      1 
ATOM   5306 C CB     . LEU A 1 450 ? 111.343 138.164 120.729 1.00 64.72  ? 441 LEU A CB     1 
ATOM   5307 C CG     . LEU A 1 450 ? 111.171 137.964 122.239 1.00 64.72  ? 441 LEU A CG     1 
ATOM   5308 C CD1    . LEU A 1 450 ? 109.710 137.828 122.647 1.00 64.72  ? 441 LEU A CD1    1 
ATOM   5309 C CD2    . LEU A 1 450 ? 111.949 136.734 122.678 1.00 64.72  ? 441 LEU A CD2    1 
ATOM   5310 H H      . LEU A 1 450 ? 110.800 138.121 118.367 1.00 64.72  ? 441 LEU A H      1 
ATOM   5311 H HA     . LEU A 1 450 ? 109.496 139.002 120.398 1.00 64.72  ? 441 LEU A HA     1 
ATOM   5312 H HB2    . LEU A 1 450 ? 111.257 137.291 120.315 1.00 64.72  ? 441 LEU A HB2    1 
ATOM   5313 H HB3    . LEU A 1 450 ? 112.245 138.492 120.590 1.00 64.72  ? 441 LEU A HB3    1 
ATOM   5314 H HG     . LEU A 1 450 ? 111.540 138.732 122.703 1.00 64.72  ? 441 LEU A HG     1 
ATOM   5315 H HD11   . LEU A 1 450 ? 109.666 137.489 123.555 1.00 64.72  ? 441 LEU A HD11   1 
ATOM   5316 H HD12   . LEU A 1 450 ? 109.286 138.699 122.601 1.00 64.72  ? 441 LEU A HD12   1 
ATOM   5317 H HD13   . LEU A 1 450 ? 109.269 137.211 122.042 1.00 64.72  ? 441 LEU A HD13   1 
ATOM   5318 H HD21   . LEU A 1 450 ? 112.899 136.916 122.599 1.00 64.72  ? 441 LEU A HD21   1 
ATOM   5319 H HD22   . LEU A 1 450 ? 111.726 136.530 123.599 1.00 64.72  ? 441 LEU A HD22   1 
ATOM   5320 H HD23   . LEU A 1 450 ? 111.706 135.987 122.109 1.00 64.72  ? 441 LEU A HD23   1 
ATOM   5321 N N      . ARG A 1 451 ? 111.702 141.101 119.450 1.00 67.62  ? 442 ARG A N      1 
ATOM   5322 C CA     . ARG A 1 451 ? 111.990 142.530 119.482 1.00 67.62  ? 442 ARG A CA     1 
ATOM   5323 C C      . ARG A 1 451 ? 112.192 143.057 118.072 1.00 67.62  ? 442 ARG A C      1 
ATOM   5324 O O      . ARG A 1 451 ? 113.093 143.862 117.813 1.00 67.62  ? 442 ARG A O      1 
ATOM   5325 C CB     . ARG A 1 451 ? 113.205 142.841 120.356 1.00 67.62  ? 442 ARG A CB     1 
ATOM   5326 C CG     . ARG A 1 451 ? 113.407 144.333 120.651 1.00 67.62  ? 442 ARG A CG     1 
ATOM   5327 C CD     . ARG A 1 451 ? 112.345 144.893 121.591 1.00 67.62  ? 442 ARG A CD     1 
ATOM   5328 N NE     . ARG A 1 451 ? 112.680 144.688 122.997 1.00 67.62  ? 442 ARG A NE     1 
ATOM   5329 C CZ     . ARG A 1 451 ? 113.364 145.545 123.745 1.00 67.62  ? 442 ARG A CZ     1 
ATOM   5330 N NH1    . ARG A 1 451 ? 113.827 146.682 123.251 1.00 67.62  ? 442 ARG A NH1    1 
ATOM   5331 N NH2    . ARG A 1 451 ? 113.588 145.255 125.024 1.00 67.62  ? 442 ARG A NH2    1 
ATOM   5332 H H      . ARG A 1 451 ? 112.164 140.658 118.875 1.00 67.62  ? 442 ARG A H      1 
ATOM   5333 H HA     . ARG A 1 451 ? 111.224 142.990 119.856 1.00 67.62  ? 442 ARG A HA     1 
ATOM   5334 H HB2    . ARG A 1 451 ? 113.099 142.386 121.206 1.00 67.62  ? 442 ARG A HB2    1 
ATOM   5335 H HB3    . ARG A 1 451 ? 114.002 142.516 119.909 1.00 67.62  ? 442 ARG A HB3    1 
ATOM   5336 H HG2    . ARG A 1 451 ? 114.271 144.453 121.074 1.00 67.62  ? 442 ARG A HG2    1 
ATOM   5337 H HG3    . ARG A 1 451 ? 113.370 144.843 119.828 1.00 67.62  ? 442 ARG A HG3    1 
ATOM   5338 H HD2    . ARG A 1 451 ? 112.249 145.844 121.434 1.00 67.62  ? 442 ARG A HD2    1 
ATOM   5339 H HD3    . ARG A 1 451 ? 111.501 144.447 121.423 1.00 67.62  ? 442 ARG A HD3    1 
ATOM   5340 H HE     . ARG A 1 451 ? 112.375 143.980 123.379 1.00 67.62  ? 442 ARG A HE     1 
ATOM   5341 H HH11   . ARG A 1 451 ? 113.690 146.885 122.427 1.00 67.62  ? 442 ARG A HH11   1 
ATOM   5342 H HH12   . ARG A 1 451 ? 114.267 147.221 123.757 1.00 67.62  ? 442 ARG A HH12   1 
ATOM   5343 H HH21   . ARG A 1 451 ? 113.293 144.519 125.357 1.00 67.62  ? 442 ARG A HH21   1 
ATOM   5344 H HH22   . ARG A 1 451 ? 114.031 145.803 125.517 1.00 67.62  ? 442 ARG A HH22   1 
ATOM   5345 N N      . ASP A 1 452 ? 111.351 142.615 117.136 1.00 70.34  ? 443 ASP A N      1 
ATOM   5346 C CA     . ASP A 1 452 ? 111.355 143.228 115.816 1.00 70.34  ? 443 ASP A CA     1 
ATOM   5347 C C      . ASP A 1 452 ? 110.866 144.667 115.857 1.00 70.34  ? 443 ASP A C      1 
ATOM   5348 O O      . ASP A 1 452 ? 110.996 145.380 114.856 1.00 70.34  ? 443 ASP A O      1 
ATOM   5349 C CB     . ASP A 1 452 ? 110.496 142.431 114.841 1.00 70.34  ? 443 ASP A CB     1 
ATOM   5350 C CG     . ASP A 1 452 ? 110.514 143.021 113.448 1.00 70.34  ? 443 ASP A CG     1 
ATOM   5351 O OD1    . ASP A 1 452 ? 111.510 142.812 112.727 1.00 70.34  ? 443 ASP A OD1    1 
ATOM   5352 O OD2    . ASP A 1 452 ? 109.543 143.714 113.081 1.00 70.34  ? 443 ASP A OD2    1 
ATOM   5353 H H      . ASP A 1 452 ? 110.784 141.977 117.239 1.00 70.34  ? 443 ASP A H      1 
ATOM   5354 H HA     . ASP A 1 452 ? 112.263 143.232 115.475 1.00 70.34  ? 443 ASP A HA     1 
ATOM   5355 H HB2    . ASP A 1 452 ? 110.834 141.523 114.789 1.00 70.34  ? 443 ASP A HB2    1 
ATOM   5356 H HB3    . ASP A 1 452 ? 109.578 142.428 115.154 1.00 70.34  ? 443 ASP A HB3    1 
ATOM   5357 N N      . LYS A 1 453 ? 110.295 145.101 116.976 1.00 72.55  ? 444 LYS A N      1 
ATOM   5358 C CA     . LYS A 1 453 ? 109.999 146.504 117.216 1.00 72.55  ? 444 LYS A CA     1 
ATOM   5359 C C      . LYS A 1 453 ? 110.985 147.034 118.250 1.00 72.55  ? 444 LYS A C      1 
ATOM   5360 O O      . LYS A 1 453 ? 111.071 146.503 119.362 1.00 72.55  ? 444 LYS A O      1 
ATOM   5361 C CB     . LYS A 1 453 ? 108.560 146.686 117.696 1.00 72.55  ? 444 LYS A CB     1 
ATOM   5362 C CG     . LYS A 1 453 ? 107.509 146.414 116.630 1.00 72.55  ? 444 LYS A CG     1 
ATOM   5363 C CD     . LYS A 1 453 ? 107.655 147.361 115.448 1.00 72.55  ? 444 LYS A CD     1 
ATOM   5364 C CE     . LYS A 1 453 ? 106.460 147.289 114.516 1.00 72.55  ? 444 LYS A CE     1 
ATOM   5365 N NZ     . LYS A 1 453 ? 105.220 147.807 115.156 1.00 72.55  ? 444 LYS A NZ     1 
ATOM   5366 H H      . LYS A 1 453 ? 110.063 144.588 117.626 1.00 72.55  ? 444 LYS A H      1 
ATOM   5367 H HA     . LYS A 1 453 ? 110.123 147.009 116.397 1.00 72.55  ? 444 LYS A HA     1 
ATOM   5368 H HB2    . LYS A 1 453 ? 108.399 146.075 118.432 1.00 72.55  ? 444 LYS A HB2    1 
ATOM   5369 H HB3    . LYS A 1 453 ? 108.444 147.601 117.997 1.00 72.55  ? 444 LYS A HB3    1 
ATOM   5370 H HG2    . LYS A 1 453 ? 107.609 145.505 116.305 1.00 72.55  ? 444 LYS A HG2    1 
ATOM   5371 H HG3    . LYS A 1 453 ? 106.627 146.538 117.013 1.00 72.55  ? 444 LYS A HG3    1 
ATOM   5372 H HD2    . LYS A 1 453 ? 107.733 148.271 115.775 1.00 72.55  ? 444 LYS A HD2    1 
ATOM   5373 H HD3    . LYS A 1 453 ? 108.445 147.119 114.940 1.00 72.55  ? 444 LYS A HD3    1 
ATOM   5374 H HE2    . LYS A 1 453 ? 106.639 147.824 113.727 1.00 72.55  ? 444 LYS A HE2    1 
ATOM   5375 H HE3    . LYS A 1 453 ? 106.307 146.365 114.265 1.00 72.55  ? 444 LYS A HE3    1 
ATOM   5376 H HZ1    . LYS A 1 453 ? 104.541 147.763 114.582 1.00 72.55  ? 444 LYS A HZ1    1 
ATOM   5377 H HZ2    . LYS A 1 453 ? 105.022 147.322 115.875 1.00 72.55  ? 444 LYS A HZ2    1 
ATOM   5378 H HZ3    . LYS A 1 453 ? 105.336 148.655 115.402 1.00 72.55  ? 444 LYS A HZ3    1 
ATOM   5379 N N      . LEU A 1 454 ? 111.730 148.074 117.877 1.00 70.93  ? 445 LEU A N      1 
ATOM   5380 C CA     . LEU A 1 454 ? 112.670 148.742 118.774 1.00 70.93  ? 445 LEU A CA     1 
ATOM   5381 C C      . LEU A 1 454 ? 113.726 147.767 119.301 1.00 70.93  ? 445 LEU A C      1 
ATOM   5382 O O      . LEU A 1 454 ? 113.793 147.470 120.494 1.00 70.93  ? 445 LEU A O      1 
ATOM   5383 C CB     . LEU A 1 454 ? 111.927 149.414 119.934 1.00 70.93  ? 445 LEU A CB     1 
ATOM   5384 C CG     . LEU A 1 454 ? 110.916 150.501 119.568 1.00 70.93  ? 445 LEU A CG     1 
ATOM   5385 C CD1    . LEU A 1 454 ? 110.185 150.979 120.813 1.00 70.93  ? 445 LEU A CD1    1 
ATOM   5386 C CD2    . LEU A 1 454 ? 111.599 151.664 118.865 1.00 70.93  ? 445 LEU A CD2    1 
ATOM   5387 H H      . LEU A 1 454 ? 111.708 148.419 117.090 1.00 70.93  ? 445 LEU A H      1 
ATOM   5388 H HA     . LEU A 1 454 ? 113.134 149.434 118.278 1.00 70.93  ? 445 LEU A HA     1 
ATOM   5389 H HB2    . LEU A 1 454 ? 111.447 148.729 120.425 1.00 70.93  ? 445 LEU A HB2    1 
ATOM   5390 H HB3    . LEU A 1 454 ? 112.585 149.821 120.519 1.00 70.93  ? 445 LEU A HB3    1 
ATOM   5391 H HG     . LEU A 1 454 ? 110.258 150.128 118.961 1.00 70.93  ? 445 LEU A HG     1 
ATOM   5392 H HD11   . LEU A 1 454 ? 109.538 151.655 120.560 1.00 70.93  ? 445 LEU A HD11   1 
ATOM   5393 H HD12   . LEU A 1 454 ? 109.733 150.224 121.222 1.00 70.93  ? 445 LEU A HD12   1 
ATOM   5394 H HD13   . LEU A 1 454 ? 110.831 151.353 121.433 1.00 70.93  ? 445 LEU A HD13   1 
ATOM   5395 H HD21   . LEU A 1 454 ? 110.958 152.383 118.752 1.00 70.93  ? 445 LEU A HD21   1 
ATOM   5396 H HD22   . LEU A 1 454 ? 112.344 151.966 119.408 1.00 70.93  ? 445 LEU A HD22   1 
ATOM   5397 H HD23   . LEU A 1 454 ? 111.919 151.365 118.000 1.00 70.93  ? 445 LEU A HD23   1 
ATOM   5398 N N      . GLY A 1 455 ? 114.553 147.269 118.391 1.00 66.97  ? 446 GLY A N      1 
ATOM   5399 C CA     . GLY A 1 455 ? 115.690 146.473 118.812 1.00 66.97  ? 446 GLY A CA     1 
ATOM   5400 C C      . GLY A 1 455 ? 116.170 145.550 117.704 1.00 66.97  ? 446 GLY A C      1 
ATOM   5401 O O      . GLY A 1 455 ? 115.817 145.714 116.539 1.00 66.97  ? 446 GLY A O      1 
ATOM   5402 H H      . GLY A 1 455 ? 114.480 147.375 117.540 1.00 66.97  ? 446 GLY A H      1 
ATOM   5403 H HA2    . GLY A 1 455 ? 116.421 147.058 119.065 1.00 66.97  ? 446 GLY A HA2    1 
ATOM   5404 H HA3    . GLY A 1 455 ? 115.446 145.933 119.579 1.00 66.97  ? 446 GLY A HA3    1 
ATOM   5405 N N      . SER A 1 456 ? 116.990 144.585 118.116 1.00 65.86  ? 447 SER A N      1 
ATOM   5406 C CA     . SER A 1 456 ? 117.570 143.583 117.235 1.00 65.86  ? 447 SER A CA     1 
ATOM   5407 C C      . SER A 1 456 ? 117.538 142.248 117.966 1.00 65.86  ? 447 SER A C      1 
ATOM   5408 O O      . SER A 1 456 ? 116.829 142.080 118.962 1.00 65.86  ? 447 SER A O      1 
ATOM   5409 C CB     . SER A 1 456 ? 119.000 143.962 116.840 1.00 65.86  ? 447 SER A CB     1 
ATOM   5410 O OG     . SER A 1 456 ? 119.888 143.718 117.918 1.00 65.86  ? 447 SER A OG     1 
ATOM   5411 H H      . SER A 1 456 ? 117.236 144.492 118.935 1.00 65.86  ? 447 SER A H      1 
ATOM   5412 H HA     . SER A 1 456 ? 117.036 143.509 116.428 1.00 65.86  ? 447 SER A HA     1 
ATOM   5413 H HB2    . SER A 1 456 ? 119.274 143.429 116.076 1.00 65.86  ? 447 SER A HB2    1 
ATOM   5414 H HB3    . SER A 1 456 ? 119.023 144.905 116.617 1.00 65.86  ? 447 SER A HB3    1 
ATOM   5415 H HG     . SER A 1 456 ? 120.669 143.940 117.702 1.00 65.86  ? 447 SER A HG     1 
ATOM   5416 N N      . TYR A 1 457 ? 118.324 141.291 117.478 1.00 62.26  ? 448 TYR A N      1 
ATOM   5417 C CA     . TYR A 1 457 ? 118.393 139.990 118.126 1.00 62.26  ? 448 TYR A CA     1 
ATOM   5418 C C      . TYR A 1 457 ? 119.044 140.052 119.499 1.00 62.26  ? 448 TYR A C      1 
ATOM   5419 O O      . TYR A 1 457 ? 118.991 139.060 120.235 1.00 62.26  ? 448 TYR A O      1 
ATOM   5420 C CB     . TYR A 1 457 ? 119.154 139.011 117.240 1.00 62.26  ? 448 TYR A CB     1 
ATOM   5421 C CG     . TYR A 1 457 ? 118.420 138.687 115.969 1.00 62.26  ? 448 TYR A CG     1 
ATOM   5422 C CD1    . TYR A 1 457 ? 117.420 137.734 115.955 1.00 62.26  ? 448 TYR A CD1    1 
ATOM   5423 C CD2    . TYR A 1 457 ? 118.719 139.340 114.787 1.00 62.26  ? 448 TYR A CD2    1 
ATOM   5424 C CE1    . TYR A 1 457 ? 116.742 137.437 114.803 1.00 62.26  ? 448 TYR A CE1    1 
ATOM   5425 C CE2    . TYR A 1 457 ? 118.045 139.047 113.624 1.00 62.26  ? 448 TYR A CE2    1 
ATOM   5426 C CZ     . TYR A 1 457 ? 117.057 138.093 113.638 1.00 62.26  ? 448 TYR A CZ     1 
ATOM   5427 O OH     . TYR A 1 457 ? 116.376 137.790 112.482 1.00 62.26  ? 448 TYR A OH     1 
ATOM   5428 H H      . TYR A 1 457 ? 118.822 141.370 116.782 1.00 62.26  ? 448 TYR A H      1 
ATOM   5429 H HA     . TYR A 1 457 ? 117.493 139.649 118.241 1.00 62.26  ? 448 TYR A HA     1 
ATOM   5430 H HB2    . TYR A 1 457 ? 120.010 139.399 117.000 1.00 62.26  ? 448 TYR A HB2    1 
ATOM   5431 H HB3    . TYR A 1 457 ? 119.291 138.183 117.727 1.00 62.26  ? 448 TYR A HB3    1 
ATOM   5432 H HD1    . TYR A 1 457 ? 117.203 137.286 116.741 1.00 62.26  ? 448 TYR A HD1    1 
ATOM   5433 H HD2    . TYR A 1 457 ? 119.389 139.985 114.778 1.00 62.26  ? 448 TYR A HD2    1 
ATOM   5434 H HE1    . TYR A 1 457 ? 116.073 136.792 114.810 1.00 62.26  ? 448 TYR A HE1    1 
ATOM   5435 H HE2    . TYR A 1 457 ? 118.258 139.491 112.835 1.00 62.26  ? 448 TYR A HE2    1 
ATOM   5436 H HH     . TYR A 1 457 ? 116.668 138.255 111.847 1.00 62.26  ? 448 TYR A HH     1 
ATOM   5437 N N      . ASP A 1 458 ? 119.661 141.179 119.853 1.00 65.38  ? 449 ASP A N      1 
ATOM   5438 C CA     . ASP A 1 458 ? 120.324 141.291 121.147 1.00 65.38  ? 449 ASP A CA     1 
ATOM   5439 C C      . ASP A 1 458 ? 119.383 140.899 122.281 1.00 65.38  ? 449 ASP A C      1 
ATOM   5440 O O      . ASP A 1 458 ? 119.753 140.134 123.178 1.00 65.38  ? 449 ASP A O      1 
ATOM   5441 C CB     . ASP A 1 458 ? 120.841 142.718 121.338 1.00 65.38  ? 449 ASP A CB     1 
ATOM   5442 C CG     . ASP A 1 458 ? 121.855 142.828 122.457 1.00 65.38  ? 449 ASP A CG     1 
ATOM   5443 O OD1    . ASP A 1 458 ? 122.132 141.802 123.113 1.00 65.38  ? 449 ASP A OD1    1 
ATOM   5444 O OD2    . ASP A 1 458 ? 122.379 143.940 122.677 1.00 65.38  ? 449 ASP A OD2    1 
ATOM   5445 H H      . ASP A 1 458 ? 119.712 141.886 119.366 1.00 65.38  ? 449 ASP A H      1 
ATOM   5446 H HA     . ASP A 1 458 ? 121.085 140.689 121.166 1.00 65.38  ? 449 ASP A HA     1 
ATOM   5447 H HB2    . ASP A 1 458 ? 121.266 143.011 120.518 1.00 65.38  ? 449 ASP A HB2    1 
ATOM   5448 H HB3    . ASP A 1 458 ? 120.094 143.299 121.551 1.00 65.38  ? 449 ASP A HB3    1 
ATOM   5449 N N      . VAL A 1 459 ? 118.151 141.410 122.250 1.00 62.00  ? 450 VAL A N      1 
ATOM   5450 C CA     . VAL A 1 459 ? 117.186 141.091 123.297 1.00 62.00  ? 450 VAL A CA     1 
ATOM   5451 C C      . VAL A 1 459 ? 116.477 139.769 123.043 1.00 62.00  ? 450 VAL A C      1 
ATOM   5452 O O      . VAL A 1 459 ? 115.839 139.231 123.955 1.00 62.00  ? 450 VAL A O      1 
ATOM   5453 C CB     . VAL A 1 459 ? 116.151 142.220 123.433 1.00 62.00  ? 450 VAL A CB     1 
ATOM   5454 C CG1    . VAL A 1 459 ? 115.113 141.875 124.490 1.00 62.00  ? 450 VAL A CG1    1 
ATOM   5455 C CG2    . VAL A 1 459 ? 116.839 143.535 123.765 1.00 62.00  ? 450 VAL A CG2    1 
ATOM   5456 H H      . VAL A 1 459 ? 117.853 141.937 121.639 1.00 62.00  ? 450 VAL A H      1 
ATOM   5457 H HA     . VAL A 1 459 ? 117.655 141.016 124.142 1.00 62.00  ? 450 VAL A HA     1 
ATOM   5458 H HB     . VAL A 1 459 ? 115.690 142.330 122.587 1.00 62.00  ? 450 VAL A HB     1 
ATOM   5459 H HG11   . VAL A 1 459 ? 114.465 141.260 124.113 1.00 62.00  ? 450 VAL A HG11   1 
ATOM   5460 H HG12   . VAL A 1 459 ? 114.667 142.691 124.770 1.00 62.00  ? 450 VAL A HG12   1 
ATOM   5461 H HG13   . VAL A 1 459 ? 115.558 141.467 125.249 1.00 62.00  ? 450 VAL A HG13   1 
ATOM   5462 H HG21   . VAL A 1 459 ? 117.343 143.427 124.587 1.00 62.00  ? 450 VAL A HG21   1 
ATOM   5463 H HG22   . VAL A 1 459 ? 116.166 144.224 123.877 1.00 62.00  ? 450 VAL A HG22   1 
ATOM   5464 H HG23   . VAL A 1 459 ? 117.437 143.771 123.039 1.00 62.00  ? 450 VAL A HG23   1 
ATOM   5465 N N      . ALA A 1 460 ? 116.570 139.228 121.832 1.00 61.51  ? 451 ALA A N      1 
ATOM   5466 C CA     . ALA A 1 460 ? 115.847 138.011 121.492 1.00 61.51  ? 451 ALA A CA     1 
ATOM   5467 C C      . ALA A 1 460 ? 116.635 136.745 121.786 1.00 61.51  ? 451 ALA A C      1 
ATOM   5468 O O      . ALA A 1 460 ? 116.030 135.686 121.984 1.00 61.51  ? 451 ALA A O      1 
ATOM   5469 C CB     . ALA A 1 460 ? 115.460 138.026 120.012 1.00 61.51  ? 451 ALA A CB     1 
ATOM   5470 H H      . ALA A 1 460 ? 117.045 139.547 121.191 1.00 61.51  ? 451 ALA A H      1 
ATOM   5471 H HA     . ALA A 1 460 ? 115.028 137.977 122.012 1.00 61.51  ? 451 ALA A HA     1 
ATOM   5472 H HB1    . ALA A 1 460 ? 116.266 138.074 119.476 1.00 61.51  ? 451 ALA A HB1    1 
ATOM   5473 H HB2    . ALA A 1 460 ? 114.974 137.212 119.806 1.00 61.51  ? 451 ALA A HB2    1 
ATOM   5474 H HB3    . ALA A 1 460 ? 114.900 138.799 119.839 1.00 61.51  ? 451 ALA A HB3    1 
ATOM   5475 N N      . PHE A 1 461 ? 117.967 136.816 121.805 1.00 61.11  ? 452 PHE A N      1 
ATOM   5476 C CA     . PHE A 1 461 ? 118.749 135.602 122.022 1.00 61.11  ? 452 PHE A CA     1 
ATOM   5477 C C      . PHE A 1 461 ? 118.760 135.176 123.487 1.00 61.11  ? 452 PHE A C      1 
ATOM   5478 O O      . PHE A 1 461 ? 118.856 133.978 123.775 1.00 61.11  ? 452 PHE A O      1 
ATOM   5479 C CB     . PHE A 1 461 ? 120.175 135.785 121.510 1.00 61.11  ? 452 PHE A CB     1 
ATOM   5480 C CG     . PHE A 1 461 ? 120.396 135.209 120.143 1.00 61.11  ? 452 PHE A CG     1 
ATOM   5481 C CD1    . PHE A 1 461 ? 120.358 133.842 119.944 1.00 61.11  ? 452 PHE A CD1    1 
ATOM   5482 C CD2    . PHE A 1 461 ? 120.635 136.030 119.059 1.00 61.11  ? 452 PHE A CD2    1 
ATOM   5483 C CE1    . PHE A 1 461 ? 120.554 133.306 118.692 1.00 61.11  ? 452 PHE A CE1    1 
ATOM   5484 C CE2    . PHE A 1 461 ? 120.833 135.498 117.804 1.00 61.11  ? 452 PHE A CE2    1 
ATOM   5485 C CZ     . PHE A 1 461 ? 120.792 134.134 117.622 1.00 61.11  ? 452 PHE A CZ     1 
ATOM   5486 H H      . PHE A 1 461 ? 118.429 137.533 121.696 1.00 61.11  ? 452 PHE A H      1 
ATOM   5487 H HA     . PHE A 1 461 ? 118.344 134.881 121.514 1.00 61.11  ? 452 PHE A HA     1 
ATOM   5488 H HB2    . PHE A 1 461 ? 120.379 136.732 121.471 1.00 61.11  ? 452 PHE A HB2    1 
ATOM   5489 H HB3    . PHE A 1 461 ? 120.785 135.342 122.121 1.00 61.11  ? 452 PHE A HB3    1 
ATOM   5490 H HD1    . PHE A 1 461 ? 120.197 133.277 120.665 1.00 61.11  ? 452 PHE A HD1    1 
ATOM   5491 H HD2    . PHE A 1 461 ? 120.662 136.952 119.178 1.00 61.11  ? 452 PHE A HD2    1 
ATOM   5492 H HE1    . PHE A 1 461 ? 120.528 132.384 118.571 1.00 61.11  ? 452 PHE A HE1    1 
ATOM   5493 H HE2    . PHE A 1 461 ? 120.994 136.059 117.081 1.00 61.11  ? 452 PHE A HE2    1 
ATOM   5494 H HZ     . PHE A 1 461 ? 120.926 133.773 116.776 1.00 61.11  ? 452 PHE A HZ     1 
ATOM   5495 N N      . TYR A 1 462 ? 118.673 136.123 124.423 1.00 62.70  ? 453 TYR A N      1 
ATOM   5496 C CA     . TYR A 1 462 ? 118.602 135.753 125.834 1.00 62.70  ? 453 TYR A CA     1 
ATOM   5497 C C      . TYR A 1 462 ? 117.435 134.808 126.086 1.00 62.70  ? 453 TYR A C      1 
ATOM   5498 O O      . TYR A 1 462 ? 117.624 133.657 126.495 1.00 62.70  ? 453 TYR A O      1 
ATOM   5499 C CB     . TYR A 1 462 ? 118.463 137.001 126.708 1.00 62.70  ? 453 TYR A CB     1 
ATOM   5500 C CG     . TYR A 1 462 ? 119.684 137.885 126.776 1.00 62.70  ? 453 TYR A CG     1 
ATOM   5501 C CD1    . TYR A 1 462 ? 120.961 137.361 126.666 1.00 62.70  ? 453 TYR A CD1    1 
ATOM   5502 C CD2    . TYR A 1 462 ? 119.553 139.252 126.964 1.00 62.70  ? 453 TYR A CD2    1 
ATOM   5503 C CE1    . TYR A 1 462 ? 122.070 138.175 126.736 1.00 62.70  ? 453 TYR A CE1    1 
ATOM   5504 C CE2    . TYR A 1 462 ? 120.652 140.070 127.034 1.00 62.70  ? 453 TYR A CE2    1 
ATOM   5505 C CZ     . TYR A 1 462 ? 121.908 139.529 126.920 1.00 62.70  ? 453 TYR A CZ     1 
ATOM   5506 O OH     . TYR A 1 462 ? 123.005 140.350 126.991 1.00 62.70  ? 453 TYR A OH     1 
ATOM   5507 H H      . TYR A 1 462 ? 118.655 136.969 124.271 1.00 62.70  ? 453 TYR A H      1 
ATOM   5508 H HA     . TYR A 1 462 ? 119.415 135.286 126.082 1.00 62.70  ? 453 TYR A HA     1 
ATOM   5509 H HB2    . TYR A 1 462 ? 117.734 137.539 126.363 1.00 62.70  ? 453 TYR A HB2    1 
ATOM   5510 H HB3    . TYR A 1 462 ? 118.257 136.720 127.613 1.00 62.70  ? 453 TYR A HB3    1 
ATOM   5511 H HD1    . TYR A 1 462 ? 121.073 136.446 126.542 1.00 62.70  ? 453 TYR A HD1    1 
ATOM   5512 H HD2    . TYR A 1 462 ? 118.703 139.622 127.042 1.00 62.70  ? 453 TYR A HD2    1 
ATOM   5513 H HE1    . TYR A 1 462 ? 122.923 137.812 126.659 1.00 62.70  ? 453 TYR A HE1    1 
ATOM   5514 H HE2    . TYR A 1 462 ? 120.547 140.986 127.159 1.00 62.70  ? 453 TYR A HE2    1 
ATOM   5515 H HH     . TYR A 1 462 ? 123.709 139.898 126.912 1.00 62.70  ? 453 TYR A HH     1 
ATOM   5516 N N      . LEU A 1 463 ? 116.213 135.278 125.831 1.00 63.75  ? 454 LEU A N      1 
ATOM   5517 C CA     . LEU A 1 463 ? 115.032 134.470 126.106 1.00 63.75  ? 454 LEU A CA     1 
ATOM   5518 C C      . LEU A 1 463 ? 115.037 133.159 125.336 1.00 63.75  ? 454 LEU A C      1 
ATOM   5519 O O      . LEU A 1 463 ? 114.353 132.216 125.743 1.00 63.75  ? 454 LEU A O      1 
ATOM   5520 C CB     . LEU A 1 463 ? 113.766 135.260 125.779 1.00 63.75  ? 454 LEU A CB     1 
ATOM   5521 C CG     . LEU A 1 463 ? 113.533 136.501 126.641 1.00 63.75  ? 454 LEU A CG     1 
ATOM   5522 C CD1    . LEU A 1 463 ? 112.293 137.244 126.180 1.00 63.75  ? 454 LEU A CD1    1 
ATOM   5523 C CD2    . LEU A 1 463 ? 113.416 136.124 128.108 1.00 63.75  ? 454 LEU A CD2    1 
ATOM   5524 H H      . LEU A 1 463 ? 116.044 136.055 125.502 1.00 63.75  ? 454 LEU A H      1 
ATOM   5525 H HA     . LEU A 1 463 ? 115.017 134.251 127.050 1.00 63.75  ? 454 LEU A HA     1 
ATOM   5526 H HB2    . LEU A 1 463 ? 113.814 135.550 124.855 1.00 63.75  ? 454 LEU A HB2    1 
ATOM   5527 H HB3    . LEU A 1 463 ? 113.001 134.675 125.895 1.00 63.75  ? 454 LEU A HB3    1 
ATOM   5528 H HG     . LEU A 1 463 ? 114.291 137.097 126.545 1.00 63.75  ? 454 LEU A HG     1 
ATOM   5529 H HD11   . LEU A 1 463 ? 112.488 137.690 125.342 1.00 63.75  ? 454 LEU A HD11   1 
ATOM   5530 H HD12   . LEU A 1 463 ? 112.050 137.898 126.853 1.00 63.75  ? 454 LEU A HD12   1 
ATOM   5531 H HD13   . LEU A 1 463 ? 111.571 136.608 126.060 1.00 63.75  ? 454 LEU A HD13   1 
ATOM   5532 H HD21   . LEU A 1 463 ? 112.775 135.401 128.197 1.00 63.75  ? 454 LEU A HD21   1 
ATOM   5533 H HD22   . LEU A 1 463 ? 113.115 136.897 128.610 1.00 63.75  ? 454 LEU A HD22   1 
ATOM   5534 H HD23   . LEU A 1 463 ? 114.284 135.838 128.433 1.00 63.75  ? 454 LEU A HD23   1 
ATOM   5535 N N      . ALA A 1 464 ? 115.787 133.075 124.238 1.00 61.58  ? 455 ALA A N      1 
ATOM   5536 C CA     . ALA A 1 464 ? 115.974 131.788 123.586 1.00 61.58  ? 455 ALA A CA     1 
ATOM   5537 C C      . ALA A 1 464 ? 116.799 130.843 124.443 1.00 61.58  ? 455 ALA A C      1 
ATOM   5538 O O      . ALA A 1 464 ? 116.865 129.648 124.140 1.00 61.58  ? 455 ALA A O      1 
ATOM   5539 C CB     . ALA A 1 464 ? 116.643 131.975 122.226 1.00 61.58  ? 455 ALA A CB     1 
ATOM   5540 H H      . ALA A 1 464 ? 116.189 133.735 123.860 1.00 61.58  ? 455 ALA A H      1 
ATOM   5541 H HA     . ALA A 1 464 ? 115.106 131.381 123.439 1.00 61.58  ? 455 ALA A HA     1 
ATOM   5542 H HB1    . ALA A 1 464 ? 116.083 132.543 121.674 1.00 61.58  ? 455 ALA A HB1    1 
ATOM   5543 H HB2    . ALA A 1 464 ? 116.750 131.108 121.805 1.00 61.58  ? 455 ALA A HB2    1 
ATOM   5544 H HB3    . ALA A 1 464 ? 117.511 132.390 122.354 1.00 61.58  ? 455 ALA A HB3    1 
ATOM   5545 N N      . GLY A 1 465 ? 117.429 131.351 125.500 1.00 63.99  ? 456 GLY A N      1 
ATOM   5546 C CA     . GLY A 1 465 ? 118.263 130.562 126.377 1.00 63.99  ? 456 GLY A CA     1 
ATOM   5547 C C      . GLY A 1 465 ? 117.646 130.140 127.692 1.00 63.99  ? 456 GLY A C      1 
ATOM   5548 O O      . GLY A 1 465 ? 118.305 129.438 128.465 1.00 63.99  ? 456 GLY A O      1 
ATOM   5549 H H      . GLY A 1 465 ? 117.386 132.177 125.730 1.00 63.99  ? 456 GLY A H      1 
ATOM   5550 H HA2    . GLY A 1 465 ? 118.536 129.758 125.909 1.00 63.99  ? 456 GLY A HA2    1 
ATOM   5551 H HA3    . GLY A 1 465 ? 119.064 131.071 126.580 1.00 63.99  ? 456 GLY A HA3    1 
ATOM   5552 N N      . VAL A 1 466 ? 116.409 130.533 127.979 1.00 61.78  ? 457 VAL A N      1 
ATOM   5553 C CA     . VAL A 1 466 ? 115.766 130.178 129.243 1.00 61.78  ? 457 VAL A CA     1 
ATOM   5554 C C      . VAL A 1 466 ? 115.212 128.757 129.194 1.00 61.78  ? 457 VAL A C      1 
ATOM   5555 O O      . VAL A 1 466 ? 115.437 127.984 130.135 1.00 61.78  ? 457 VAL A O      1 
ATOM   5556 C CB     . VAL A 1 466 ? 114.658 131.179 129.604 1.00 61.78  ? 457 VAL A CB     1 
ATOM   5557 C CG1    . VAL A 1 466 ? 113.778 130.621 130.708 1.00 61.78  ? 457 VAL A CG1    1 
ATOM   5558 C CG2    . VAL A 1 466 ? 115.267 132.498 130.035 1.00 61.78  ? 457 VAL A CG2    1 
ATOM   5559 H H      . VAL A 1 466 ? 115.917 131.010 127.457 1.00 61.78  ? 457 VAL A H      1 
ATOM   5560 H HA     . VAL A 1 466 ? 116.432 130.209 129.948 1.00 61.78  ? 457 VAL A HA     1 
ATOM   5561 H HB     . VAL A 1 466 ? 114.102 131.346 128.828 1.00 61.78  ? 457 VAL A HB     1 
ATOM   5562 H HG11   . VAL A 1 466 ? 113.145 129.992 130.328 1.00 61.78  ? 457 VAL A HG11   1 
ATOM   5563 H HG12   . VAL A 1 466 ? 113.300 131.354 131.127 1.00 61.78  ? 457 VAL A HG12   1 
ATOM   5564 H HG13   . VAL A 1 466 ? 114.338 130.178 131.365 1.00 61.78  ? 457 VAL A HG13   1 
ATOM   5565 H HG21   . VAL A 1 466 ? 115.810 132.350 130.825 1.00 61.78  ? 457 VAL A HG21   1 
ATOM   5566 H HG22   . VAL A 1 466 ? 114.555 133.125 130.235 1.00 61.78  ? 457 VAL A HG22   1 
ATOM   5567 H HG23   . VAL A 1 466 ? 115.818 132.841 129.314 1.00 61.78  ? 457 VAL A HG23   1 
ATOM   5568 N N      . PRO A 1 467 ? 114.493 128.365 128.146 1.00 62.66  ? 458 PRO A N      1 
ATOM   5569 C CA     . PRO A 1 467 ? 113.812 127.061 128.155 1.00 62.66  ? 458 PRO A CA     1 
ATOM   5570 C C      . PRO A 1 467 ? 114.767 125.907 128.411 1.00 62.66  ? 458 PRO A C      1 
ATOM   5571 O O      . PRO A 1 467 ? 114.378 124.915 129.050 1.00 62.66  ? 458 PRO A O      1 
ATOM   5572 C CB     . PRO A 1 467 ? 113.200 126.975 126.750 1.00 62.66  ? 458 PRO A CB     1 
ATOM   5573 C CG     . PRO A 1 467 ? 113.037 128.376 126.329 1.00 62.66  ? 458 PRO A CG     1 
ATOM   5574 C CD     . PRO A 1 467 ? 114.185 129.127 126.925 1.00 62.66  ? 458 PRO A CD     1 
ATOM   5575 H HA     . PRO A 1 467 ? 113.105 127.051 128.819 1.00 62.66  ? 458 PRO A HA     1 
ATOM   5576 H HB2    . PRO A 1 467 ? 113.799 126.500 126.154 1.00 62.66  ? 458 PRO A HB2    1 
ATOM   5577 H HB3    . PRO A 1 467 ? 112.339 126.530 126.797 1.00 62.66  ? 458 PRO A HB3    1 
ATOM   5578 H HG2    . PRO A 1 467 ? 113.064 128.427 125.361 1.00 62.66  ? 458 PRO A HG2    1 
ATOM   5579 H HG3    . PRO A 1 467 ? 112.195 128.720 126.665 1.00 62.66  ? 458 PRO A HG3    1 
ATOM   5580 H HD2    . PRO A 1 467 ? 114.943 129.120 126.320 1.00 62.66  ? 458 PRO A HD2    1 
ATOM   5581 H HD3    . PRO A 1 467 ? 113.914 130.031 127.143 1.00 62.66  ? 458 PRO A HD3    1 
ATOM   5582 N N      . PRO A 1 468 ? 115.998 125.960 127.889 1.00 62.90  ? 459 PRO A N      1 
ATOM   5583 C CA     . PRO A 1 468 ? 116.917 124.834 128.126 1.00 62.90  ? 459 PRO A CA     1 
ATOM   5584 C C      . PRO A 1 468 ? 117.155 124.538 129.596 1.00 62.90  ? 459 PRO A C      1 
ATOM   5585 O O      . PRO A 1 468 ? 117.236 123.366 129.979 1.00 62.90  ? 459 PRO A O      1 
ATOM   5586 C CB     . PRO A 1 468 ? 118.200 125.286 127.419 1.00 62.90  ? 459 PRO A CB     1 
ATOM   5587 C CG     . PRO A 1 468 ? 117.729 126.170 126.338 1.00 62.90  ? 459 PRO A CG     1 
ATOM   5588 C CD     . PRO A 1 468 ? 116.547 126.900 126.896 1.00 62.90  ? 459 PRO A CD     1 
ATOM   5589 H HA     . PRO A 1 468 ? 116.582 124.034 127.693 1.00 62.90  ? 459 PRO A HA     1 
ATOM   5590 H HB2    . PRO A 1 468 ? 118.765 125.771 128.041 1.00 62.90  ? 459 PRO A HB2    1 
ATOM   5591 H HB3    . PRO A 1 468 ? 118.665 124.515 127.057 1.00 62.90  ? 459 PRO A HB3    1 
ATOM   5592 H HG2    . PRO A 1 468 ? 118.433 126.793 126.097 1.00 62.90  ? 459 PRO A HG2    1 
ATOM   5593 H HG3    . PRO A 1 468 ? 117.468 125.635 125.572 1.00 62.90  ? 459 PRO A HG3    1 
ATOM   5594 H HD2    . PRO A 1 468 ? 116.837 127.714 127.330 1.00 62.90  ? 459 PRO A HD2    1 
ATOM   5595 H HD3    . PRO A 1 468 ? 115.902 127.078 126.195 1.00 62.90  ? 459 PRO A HD3    1 
ATOM   5596 N N      . LEU A 1 469 ? 117.274 125.567 130.437 1.00 62.07  ? 460 LEU A N      1 
ATOM   5597 C CA     . LEU A 1 469 ? 117.522 125.326 131.854 1.00 62.07  ? 460 LEU A CA     1 
ATOM   5598 C C      . LEU A 1 469 ? 116.338 124.626 132.510 1.00 62.07  ? 460 LEU A C      1 
ATOM   5599 O O      . LEU A 1 469 ? 116.519 123.681 133.290 1.00 62.07  ? 460 LEU A O      1 
ATOM   5600 C CB     . LEU A 1 469 ? 117.824 126.647 132.557 1.00 62.07  ? 460 LEU A CB     1 
ATOM   5601 C CG     . LEU A 1 469 ? 118.926 127.487 131.909 1.00 62.07  ? 460 LEU A CG     1 
ATOM   5602 C CD1    . LEU A 1 469 ? 119.159 128.760 132.699 1.00 62.07  ? 460 LEU A CD1    1 
ATOM   5603 C CD2    . LEU A 1 469 ? 120.210 126.692 131.790 1.00 62.07  ? 460 LEU A CD2    1 
ATOM   5604 H H      . LEU A 1 469 ? 117.214 126.395 130.215 1.00 62.07  ? 460 LEU A H      1 
ATOM   5605 H HA     . LEU A 1 469 ? 118.296 124.750 131.947 1.00 62.07  ? 460 LEU A HA     1 
ATOM   5606 H HB2    . LEU A 1 469 ? 117.016 127.183 132.567 1.00 62.07  ? 460 LEU A HB2    1 
ATOM   5607 H HB3    . LEU A 1 469 ? 118.099 126.456 133.467 1.00 62.07  ? 460 LEU A HB3    1 
ATOM   5608 H HG     . LEU A 1 469 ? 118.647 127.739 131.015 1.00 62.07  ? 460 LEU A HG     1 
ATOM   5609 H HD11   . LEU A 1 469 ? 119.872 129.266 132.280 1.00 62.07  ? 460 LEU A HD11   1 
ATOM   5610 H HD12   . LEU A 1 469 ? 119.408 128.526 133.607 1.00 62.07  ? 460 LEU A HD12   1 
ATOM   5611 H HD13   . LEU A 1 469 ? 118.341 129.282 132.704 1.00 62.07  ? 460 LEU A HD13   1 
ATOM   5612 H HD21   . LEU A 1 469 ? 120.924 127.285 131.508 1.00 62.07  ? 460 LEU A HD21   1 
ATOM   5613 H HD22   . LEU A 1 469 ? 120.423 126.307 132.655 1.00 62.07  ? 460 LEU A HD22   1 
ATOM   5614 H HD23   . LEU A 1 469 ? 120.088 125.987 131.135 1.00 62.07  ? 460 LEU A HD23   1 
ATOM   5615 N N      . ILE A 1 470 ? 115.120 125.071 132.203 1.00 62.35  ? 461 ILE A N      1 
ATOM   5616 C CA     . ILE A 1 470 ? 113.937 124.414 132.746 1.00 62.35  ? 461 ILE A CA     1 
ATOM   5617 C C      . ILE A 1 470 ? 113.886 122.967 132.286 1.00 62.35  ? 461 ILE A C      1 
ATOM   5618 O O      . ILE A 1 470 ? 113.579 122.060 133.070 1.00 62.35  ? 461 ILE A O      1 
ATOM   5619 C CB     . ILE A 1 470 ? 112.665 125.178 132.337 1.00 62.35  ? 461 ILE A CB     1 
ATOM   5620 C CG1    . ILE A 1 470 ? 112.645 126.557 132.997 1.00 62.35  ? 461 ILE A CG1    1 
ATOM   5621 C CG2    . ILE A 1 470 ? 111.426 124.374 132.709 1.00 62.35  ? 461 ILE A CG2    1 
ATOM   5622 C CD1    . ILE A 1 470 ? 111.520 127.449 132.523 1.00 62.35  ? 461 ILE A CD1    1 
ATOM   5623 H H      . ILE A 1 470 ? 114.955 125.742 131.691 1.00 62.35  ? 461 ILE A H      1 
ATOM   5624 H HA     . ILE A 1 470 ? 113.990 124.418 133.714 1.00 62.35  ? 461 ILE A HA     1 
ATOM   5625 H HB     . ILE A 1 470 ? 112.674 125.298 131.375 1.00 62.35  ? 461 ILE A HB     1 
ATOM   5626 H HG12   . ILE A 1 470 ? 112.548 126.442 133.956 1.00 62.35  ? 461 ILE A HG12   1 
ATOM   5627 H HG13   . ILE A 1 470 ? 113.481 127.009 132.804 1.00 62.35  ? 461 ILE A HG13   1 
ATOM   5628 H HG21   . ILE A 1 470 ? 111.332 123.629 132.095 1.00 62.35  ? 461 ILE A HG21   1 
ATOM   5629 H HG22   . ILE A 1 470 ? 110.643 124.943 132.650 1.00 62.35  ? 461 ILE A HG22   1 
ATOM   5630 H HG23   . ILE A 1 470 ? 111.525 124.046 133.617 1.00 62.35  ? 461 ILE A HG23   1 
ATOM   5631 H HD11   . ILE A 1 470 ? 111.455 127.387 131.557 1.00 62.35  ? 461 ILE A HD11   1 
ATOM   5632 H HD12   . ILE A 1 470 ? 111.712 128.364 132.783 1.00 62.35  ? 461 ILE A HD12   1 
ATOM   5633 H HD13   . ILE A 1 470 ? 110.689 127.157 132.930 1.00 62.35  ? 461 ILE A HD13   1 
ATOM   5634 N N      . GLY A 1 471 ? 114.174 122.727 131.006 1.00 63.08  ? 462 GLY A N      1 
ATOM   5635 C CA     . GLY A 1 471 ? 114.166 121.362 130.508 1.00 63.08  ? 462 GLY A CA     1 
ATOM   5636 C C      . GLY A 1 471 ? 115.184 120.488 131.212 1.00 63.08  ? 462 GLY A C      1 
ATOM   5637 O O      . GLY A 1 471 ? 114.895 119.343 131.572 1.00 63.08  ? 462 GLY A O      1 
ATOM   5638 H H      . GLY A 1 471 ? 114.373 123.326 130.422 1.00 63.08  ? 462 GLY A H      1 
ATOM   5639 H HA2    . GLY A 1 471 ? 113.285 120.976 130.634 1.00 63.08  ? 462 GLY A HA2    1 
ATOM   5640 H HA3    . GLY A 1 471 ? 114.369 121.368 129.560 1.00 63.08  ? 462 GLY A HA3    1 
ATOM   5641 N N      . GLY A 1 472 ? 116.389 121.016 131.419 1.00 63.70  ? 463 GLY A N      1 
ATOM   5642 C CA     . GLY A 1 472 ? 117.400 120.262 132.136 1.00 63.70  ? 463 GLY A CA     1 
ATOM   5643 C C      . GLY A 1 472 ? 116.973 119.929 133.551 1.00 63.70  ? 463 GLY A C      1 
ATOM   5644 O O      . GLY A 1 472 ? 117.171 118.806 134.021 1.00 63.70  ? 463 GLY A O      1 
ATOM   5645 H H      . GLY A 1 472 ? 116.639 121.796 131.156 1.00 63.70  ? 463 GLY A H      1 
ATOM   5646 H HA2    . GLY A 1 472 ? 117.580 119.433 131.666 1.00 63.70  ? 463 GLY A HA2    1 
ATOM   5647 H HA3    . GLY A 1 472 ? 118.221 120.777 132.176 1.00 63.70  ? 463 GLY A HA3    1 
ATOM   5648 N N      . ALA A 1 473 ? 116.379 120.898 134.251 1.00 62.88  ? 464 ALA A N      1 
ATOM   5649 C CA     . ALA A 1 473 ? 115.901 120.630 135.604 1.00 62.88  ? 464 ALA A CA     1 
ATOM   5650 C C      . ALA A 1 473 ? 114.837 119.539 135.597 1.00 62.88  ? 464 ALA A C      1 
ATOM   5651 O O      . ALA A 1 473 ? 114.886 118.595 136.397 1.00 62.88  ? 464 ALA A O      1 
ATOM   5652 C CB     . ALA A 1 473 ? 115.355 121.912 136.231 1.00 62.88  ? 464 ALA A CB     1 
ATOM   5653 H H      . ALA A 1 473 ? 116.245 121.700 133.972 1.00 62.88  ? 464 ALA A H      1 
ATOM   5654 H HA     . ALA A 1 473 ? 116.643 120.322 136.147 1.00 62.88  ? 464 ALA A HA     1 
ATOM   5655 H HB1    . ALA A 1 473 ? 116.064 122.572 136.266 1.00 62.88  ? 464 ALA A HB1    1 
ATOM   5656 H HB2    . ALA A 1 473 ? 114.622 122.241 135.687 1.00 62.88  ? 464 ALA A HB2    1 
ATOM   5657 H HB3    . ALA A 1 473 ? 115.040 121.716 137.127 1.00 62.88  ? 464 ALA A HB3    1 
ATOM   5658 N N      . VAL A 1 474 ? 113.874 119.641 134.679 1.00 62.62  ? 465 VAL A N      1 
ATOM   5659 C CA     . VAL A 1 474 ? 112.807 118.647 134.617 1.00 62.62  ? 465 VAL A CA     1 
ATOM   5660 C C      . VAL A 1 474 ? 113.394 117.262 134.381 1.00 62.62  ? 465 VAL A C      1 
ATOM   5661 O O      . VAL A 1 474 ? 113.012 116.286 135.037 1.00 62.62  ? 465 VAL A O      1 
ATOM   5662 C CB     . VAL A 1 474 ? 111.786 119.017 133.526 1.00 62.62  ? 465 VAL A CB     1 
ATOM   5663 C CG1    . VAL A 1 474 ? 110.797 117.882 133.321 1.00 62.62  ? 465 VAL A CG1    1 
ATOM   5664 C CG2    . VAL A 1 474 ? 111.055 120.292 133.898 1.00 62.62  ? 465 VAL A CG2    1 
ATOM   5665 H H      . VAL A 1 474 ? 113.817 120.267 134.092 1.00 62.62  ? 465 VAL A H      1 
ATOM   5666 H HA     . VAL A 1 474 ? 112.341 118.632 135.468 1.00 62.62  ? 465 VAL A HA     1 
ATOM   5667 H HB     . VAL A 1 474 ? 112.254 119.167 132.689 1.00 62.62  ? 465 VAL A HB     1 
ATOM   5668 H HG11   . VAL A 1 474 ? 109.930 118.259 133.104 1.00 62.62  ? 465 VAL A HG11   1 
ATOM   5669 H HG12   . VAL A 1 474 ? 110.733 117.361 134.137 1.00 62.62  ? 465 VAL A HG12   1 
ATOM   5670 H HG13   . VAL A 1 474 ? 111.105 117.323 132.591 1.00 62.62  ? 465 VAL A HG13   1 
ATOM   5671 H HG21   . VAL A 1 474 ? 110.496 120.120 134.672 1.00 62.62  ? 465 VAL A HG21   1 
ATOM   5672 H HG22   . VAL A 1 474 ? 110.505 120.568 133.148 1.00 62.62  ? 465 VAL A HG22   1 
ATOM   5673 H HG23   . VAL A 1 474 ? 111.703 120.982 134.104 1.00 62.62  ? 465 VAL A HG23   1 
ATOM   5674 N N      . LEU A 1 475 ? 114.337 117.156 133.444 1.00 66.32  ? 466 LEU A N      1 
ATOM   5675 C CA     . LEU A 1 475 ? 114.953 115.859 133.188 1.00 66.32  ? 466 LEU A CA     1 
ATOM   5676 C C      . LEU A 1 475 ? 115.720 115.356 134.402 1.00 66.32  ? 466 LEU A C      1 
ATOM   5677 O O      . LEU A 1 475 ? 115.708 114.153 134.684 1.00 66.32  ? 466 LEU A O      1 
ATOM   5678 C CB     . LEU A 1 475 ? 115.874 115.936 131.974 1.00 66.32  ? 466 LEU A CB     1 
ATOM   5679 C CG     . LEU A 1 475 ? 115.201 115.642 130.634 1.00 66.32  ? 466 LEU A CG     1 
ATOM   5680 C CD1    . LEU A 1 475 ? 114.272 116.772 130.229 1.00 66.32  ? 466 LEU A CD1    1 
ATOM   5681 C CD2    . LEU A 1 475 ? 116.246 115.394 129.562 1.00 66.32  ? 466 LEU A CD2    1 
ATOM   5682 H H      . LEU A 1 475 ? 114.630 117.801 132.957 1.00 66.32  ? 466 LEU A H      1 
ATOM   5683 H HA     . LEU A 1 475 ? 114.254 115.216 132.991 1.00 66.32  ? 466 LEU A HA     1 
ATOM   5684 H HB2    . LEU A 1 475 ? 116.247 116.830 131.924 1.00 66.32  ? 466 LEU A HB2    1 
ATOM   5685 H HB3    . LEU A 1 475 ? 116.590 115.292 132.089 1.00 66.32  ? 466 LEU A HB3    1 
ATOM   5686 H HG     . LEU A 1 475 ? 114.668 114.836 130.721 1.00 66.32  ? 466 LEU A HG     1 
ATOM   5687 H HD11   . LEU A 1 475 ? 113.754 116.490 129.459 1.00 66.32  ? 466 LEU A HD11   1 
ATOM   5688 H HD12   . LEU A 1 475 ? 114.804 117.549 130.001 1.00 66.32  ? 466 LEU A HD12   1 
ATOM   5689 H HD13   . LEU A 1 475 ? 113.678 116.978 130.968 1.00 66.32  ? 466 LEU A HD13   1 
ATOM   5690 H HD21   . LEU A 1 475 ? 116.813 116.178 129.488 1.00 66.32  ? 466 LEU A HD21   1 
ATOM   5691 H HD22   . LEU A 1 475 ? 116.777 114.623 129.813 1.00 66.32  ? 466 LEU A HD22   1 
ATOM   5692 H HD23   . LEU A 1 475 ? 115.798 115.228 128.718 1.00 66.32  ? 466 LEU A HD23   1 
ATOM   5693 N N      . CYS A 1 476 ? 116.395 116.248 135.129 1.00 67.09  ? 467 CYS A N      1 
ATOM   5694 C CA     . CYS A 1 476 ? 117.089 115.845 136.344 1.00 67.09  ? 467 CYS A CA     1 
ATOM   5695 C C      . CYS A 1 476 ? 116.127 115.481 137.463 1.00 67.09  ? 467 CYS A C      1 
ATOM   5696 O O      . CYS A 1 476 ? 116.561 114.916 138.472 1.00 67.09  ? 467 CYS A O      1 
ATOM   5697 C CB     . CYS A 1 476 ? 118.023 116.962 136.812 1.00 67.09  ? 467 CYS A CB     1 
ATOM   5698 S SG     . CYS A 1 476 ? 119.055 116.527 138.232 1.00 67.09  ? 467 CYS A SG     1 
ATOM   5699 H H      . CYS A 1 476 ? 116.463 117.085 134.940 1.00 67.09  ? 467 CYS A H      1 
ATOM   5700 H HA     . CYS A 1 476 ? 117.630 115.063 136.151 1.00 67.09  ? 467 CYS A HA     1 
ATOM   5701 H HB2    . CYS A 1 476 ? 118.614 117.199 136.079 1.00 67.09  ? 467 CYS A HB2    1 
ATOM   5702 H HB3    . CYS A 1 476 ? 117.487 117.731 137.063 1.00 67.09  ? 467 CYS A HB3    1 
ATOM   5703 H HG     . CYS A 1 476 ? 119.736 117.470 138.526 1.00 67.09  ? 467 CYS A HG     1 
ATOM   5704 N N      . PHE A 1 477 ? 114.841 115.781 137.306 1.00 66.96  ? 468 PHE A N      1 
ATOM   5705 C CA     . PHE A 1 477 ? 113.825 115.465 138.308 1.00 66.96  ? 468 PHE A CA     1 
ATOM   5706 C C      . PHE A 1 477 ? 113.113 114.154 137.993 1.00 66.96  ? 468 PHE A C      1 
ATOM   5707 O O      . PHE A 1 477 ? 111.915 114.019 138.249 1.00 66.96  ? 468 PHE A O      1 
ATOM   5708 C CB     . PHE A 1 477 ? 112.819 116.608 138.398 1.00 66.96  ? 468 PHE A CB     1 
ATOM   5709 C CG     . PHE A 1 477 ? 112.064 116.671 139.698 1.00 66.96  ? 468 PHE A CG     1 
ATOM   5710 C CD1    . PHE A 1 477 ? 112.118 115.638 140.619 1.00 66.96  ? 468 PHE A CD1    1 
ATOM   5711 C CD2    . PHE A 1 477 ? 111.289 117.780 139.991 1.00 66.96  ? 468 PHE A CD2    1 
ATOM   5712 C CE1    . PHE A 1 477 ? 111.418 115.712 141.803 1.00 66.96  ? 468 PHE A CE1    1 
ATOM   5713 C CE2    . PHE A 1 477 ? 110.588 117.859 141.174 1.00 66.96  ? 468 PHE A CE2    1 
ATOM   5714 C CZ     . PHE A 1 477 ? 110.651 116.823 142.082 1.00 66.96  ? 468 PHE A CZ     1 
ATOM   5715 H H      . PHE A 1 477 ? 114.523 116.182 136.615 1.00 66.96  ? 468 PHE A H      1 
ATOM   5716 H HA     . PHE A 1 477 ? 114.265 115.374 139.167 1.00 66.96  ? 468 PHE A HA     1 
ATOM   5717 H HB2    . PHE A 1 477 ? 113.292 117.448 138.288 1.00 66.96  ? 468 PHE A HB2    1 
ATOM   5718 H HB3    . PHE A 1 477 ? 112.166 116.506 137.688 1.00 66.96  ? 468 PHE A HB3    1 
ATOM   5719 H HD1    . PHE A 1 477 ? 112.632 114.885 140.440 1.00 66.96  ? 468 PHE A HD1    1 
ATOM   5720 H HD2    . PHE A 1 477 ? 111.242 118.481 139.381 1.00 66.96  ? 468 PHE A HD2    1 
ATOM   5721 H HE1    . PHE A 1 477 ? 111.462 115.013 142.415 1.00 66.96  ? 468 PHE A HE1    1 
ATOM   5722 H HE2    . PHE A 1 477 ? 110.071 118.610 141.358 1.00 66.96  ? 468 PHE A HE2    1 
ATOM   5723 H HZ     . PHE A 1 477 ? 110.179 116.874 142.881 1.00 66.96  ? 468 PHE A HZ     1 
ATOM   5724 N N      . ILE A 1 478 ? 113.819 113.175 137.434 1.00 70.30  ? 469 ILE A N      1 
ATOM   5725 C CA     . ILE A 1 478 ? 113.213 111.900 137.055 1.00 70.30  ? 469 ILE A CA     1 
ATOM   5726 C C      . ILE A 1 478 ? 113.605 110.839 138.077 1.00 70.30  ? 469 ILE A C      1 
ATOM   5727 O O      . ILE A 1 478 ? 114.797 110.688 138.379 1.00 70.30  ? 469 ILE A O      1 
ATOM   5728 C CB     . ILE A 1 478 ? 113.636 111.476 135.640 1.00 70.30  ? 469 ILE A CB     1 
ATOM   5729 C CG1    . ILE A 1 478 ? 113.163 112.506 134.616 1.00 70.30  ? 469 ILE A CG1    1 
ATOM   5730 C CG2    . ILE A 1 478 ? 113.060 110.108 135.303 1.00 70.30  ? 469 ILE A CG2    1 
ATOM   5731 C CD1    . ILE A 1 478 ? 113.691 112.271 133.219 1.00 70.30  ? 469 ILE A CD1    1 
ATOM   5732 H H      . ILE A 1 478 ? 114.660 113.223 137.266 1.00 70.30  ? 469 ILE A H      1 
ATOM   5733 H HA     . ILE A 1 478 ? 112.251 112.005 137.052 1.00 70.30  ? 469 ILE A HA     1 
ATOM   5734 H HB     . ILE A 1 478 ? 114.605 111.426 135.608 1.00 70.30  ? 469 ILE A HB     1 
ATOM   5735 H HG12   . ILE A 1 478 ? 112.195 112.473 134.573 1.00 70.30  ? 469 ILE A HG12   1 
ATOM   5736 H HG13   . ILE A 1 478 ? 113.445 113.388 134.900 1.00 70.30  ? 469 ILE A HG13   1 
ATOM   5737 H HG21   . ILE A 1 478 ? 113.451 109.439 135.885 1.00 70.30  ? 469 ILE A HG21   1 
ATOM   5738 H HG22   . ILE A 1 478 ? 112.098 110.135 135.426 1.00 70.30  ? 469 ILE A HG22   1 
ATOM   5739 H HG23   . ILE A 1 478 ? 113.267 109.895 134.380 1.00 70.30  ? 469 ILE A HG23   1 
ATOM   5740 H HD11   . ILE A 1 478 ? 114.643 112.093 133.264 1.00 70.30  ? 469 ILE A HD11   1 
ATOM   5741 H HD12   . ILE A 1 478 ? 113.229 111.510 132.833 1.00 70.30  ? 469 ILE A HD12   1 
ATOM   5742 H HD13   . ILE A 1 478 ? 113.524 113.062 132.684 1.00 70.30  ? 469 ILE A HD13   1 
ATOM   5743 N N      . PRO A 1 479 ? 112.660 110.084 138.628 1.00 76.69  ? 470 PRO A N      1 
ATOM   5744 C CA     . PRO A 1 479 ? 113.012 109.078 139.632 1.00 76.69  ? 470 PRO A CA     1 
ATOM   5745 C C      . PRO A 1 479 ? 113.712 107.876 139.016 1.00 76.69  ? 470 PRO A C      1 
ATOM   5746 O O      . PRO A 1 479 ? 113.624 107.610 137.817 1.00 76.69  ? 470 PRO A O      1 
ATOM   5747 C CB     . PRO A 1 479 ? 111.657 108.680 140.224 1.00 76.69  ? 470 PRO A CB     1 
ATOM   5748 C CG     . PRO A 1 479 ? 110.690 108.940 139.132 1.00 76.69  ? 470 PRO A CG     1 
ATOM   5749 C CD     . PRO A 1 479 ? 111.208 110.132 138.388 1.00 76.69  ? 470 PRO A CD     1 
ATOM   5750 H HA     . PRO A 1 479 ? 113.571 109.466 140.323 1.00 76.69  ? 470 PRO A HA     1 
ATOM   5751 H HB2    . PRO A 1 479 ? 111.666 107.740 140.460 1.00 76.69  ? 470 PRO A HB2    1 
ATOM   5752 H HB3    . PRO A 1 479 ? 111.467 109.231 141.001 1.00 76.69  ? 470 PRO A HB3    1 
ATOM   5753 H HG2    . PRO A 1 479 ? 110.651 108.170 138.543 1.00 76.69  ? 470 PRO A HG2    1 
ATOM   5754 H HG3    . PRO A 1 479 ? 109.817 109.127 139.511 1.00 76.69  ? 470 PRO A HG3    1 
ATOM   5755 H HD2    . PRO A 1 479 ? 111.029 110.043 137.440 1.00 76.69  ? 470 PRO A HD2    1 
ATOM   5756 H HD3    . PRO A 1 479 ? 110.831 110.948 138.752 1.00 76.69  ? 470 PRO A HD3    1 
ATOM   5757 N N      . SER A 1 480 ? 114.424 107.152 139.874 1.00 83.98  ? 471 SER A N      1 
ATOM   5758 C CA     . SER A 1 480 ? 115.142 105.951 139.469 1.00 83.98  ? 471 SER A CA     1 
ATOM   5759 C C      . SER A 1 480 ? 115.600 105.216 140.721 1.00 83.98  ? 471 SER A C      1 
ATOM   5760 O O      . SER A 1 480 ? 115.434 105.696 141.844 1.00 83.98  ? 471 SER A O      1 
ATOM   5761 C CB     . SER A 1 480 ? 116.333 106.288 138.567 1.00 30.00  ? 471 SER A CB     1 
ATOM   5762 O OG     . SER A 1 480 ? 117.103 105.130 138.292 1.00 30.00  ? 471 SER A OG     1 
ATOM   5763 H H      . SER A 1 480 ? 114.507 107.341 140.709 1.00 83.98  ? 471 SER A H      1 
ATOM   5764 H HA     . SER A 1 480 ? 114.543 105.369 138.975 1.00 83.98  ? 471 SER A HA     1 
ATOM   5765 H HB2    . SER A 1 480 ? 116.003 106.654 137.732 1.00 30.00  ? 471 SER A HB2    1 
ATOM   5766 H HB3    . SER A 1 480 ? 116.894 106.940 139.016 1.00 30.00  ? 471 SER A HB3    1 
ATOM   5767 H HG     . SER A 1 480 ? 117.771 105.333 137.824 1.00 30.00  ? 471 SER A HG     1 
ATOM   5768 N N      . ARG A 1 481 ? 116.184 104.036 140.508 1.00 88.63  ? 472 ARG A N      1 
ATOM   5769 C CA     . ARG A 1 481 ? 116.719 103.215 141.595 1.00 88.63  ? 472 ARG A CA     1 
ATOM   5770 C C      . ARG A 1 481 ? 115.659 102.937 142.656 1.00 88.63  ? 472 ARG A C      1 
ATOM   5771 O O      . ARG A 1 481 ? 115.959 102.891 143.851 1.00 88.63  ? 472 ARG A O      1 
ATOM   5772 C CB     . ARG A 1 481 ? 117.942 103.876 142.236 1.00 88.63  ? 472 ARG A CB     1 
ATOM   5773 C CG     . ARG A 1 481 ? 118.792 102.936 143.078 1.00 88.63  ? 472 ARG A CG     1 
ATOM   5774 C CD     . ARG A 1 481 ? 119.505 103.675 144.203 1.00 88.63  ? 472 ARG A CD     1 
ATOM   5775 N NE     . ARG A 1 481 ? 118.585 104.109 145.248 1.00 88.63  ? 472 ARG A NE     1 
ATOM   5776 C CZ     . ARG A 1 481 ? 118.953 104.720 146.366 1.00 88.63  ? 472 ARG A CZ     1 
ATOM   5777 N NH1    . ARG A 1 481 ? 120.222 104.994 146.619 1.00 88.63  ? 472 ARG A NH1    1 
ATOM   5778 N NH2    . ARG A 1 481 ? 118.024 105.066 147.253 1.00 88.63  ? 472 ARG A NH2    1 
ATOM   5779 H H      . ARG A 1 481 ? 116.285 103.685 139.730 1.00 88.63  ? 472 ARG A H      1 
ATOM   5780 H HA     . ARG A 1 481 ? 117.004 102.362 141.232 1.00 88.63  ? 472 ARG A HA     1 
ATOM   5781 H HB2    . ARG A 1 481 ? 118.508 104.235 141.533 1.00 88.63  ? 472 ARG A HB2    1 
ATOM   5782 H HB3    . ARG A 1 481 ? 117.639 104.595 142.812 1.00 88.63  ? 472 ARG A HB3    1 
ATOM   5783 H HG2    . ARG A 1 481 ? 118.229 102.252 143.470 1.00 88.63  ? 472 ARG A HG2    1 
ATOM   5784 H HG3    . ARG A 1 481 ? 119.467 102.528 142.514 1.00 88.63  ? 472 ARG A HG3    1 
ATOM   5785 H HD2    . ARG A 1 481 ? 120.160 103.083 144.604 1.00 88.63  ? 472 ARG A HD2    1 
ATOM   5786 H HD3    . ARG A 1 481 ? 119.944 104.461 143.841 1.00 88.63  ? 472 ARG A HD3    1 
ATOM   5787 H HE     . ARG A 1 481 ? 117.758 103.886 145.169 1.00 88.63  ? 472 ARG A HE     1 
ATOM   5788 H HH11   . ARG A 1 481 ? 120.832 104.776 146.054 1.00 88.63  ? 472 ARG A HH11   1 
ATOM   5789 H HH12   . ARG A 1 481 ? 120.437 105.391 147.351 1.00 88.63  ? 472 ARG A HH12   1 
ATOM   5790 H HH21   . ARG A 1 481 ? 117.196 104.892 147.098 1.00 88.63  ? 472 ARG A HH21   1 
ATOM   5791 H HH22   . ARG A 1 481 ? 118.252 105.463 147.981 1.00 88.63  ? 472 ARG A HH22   1 
ATOM   5792 N N      . LEU A 1 482 ? 114.413 102.751 142.234 1.00 89.42  ? 473 LEU A N      1 
ATOM   5793 C CA     . LEU A 1 482 ? 113.300 102.591 143.156 1.00 89.42  ? 473 LEU A CA     1 
ATOM   5794 C C      . LEU A 1 482 ? 112.405 101.448 142.706 1.00 89.42  ? 473 LEU A C      1 
ATOM   5795 O O      . LEU A 1 482 ? 112.260 101.180 141.509 1.00 89.42  ? 473 LEU A O      1 
ATOM   5796 C CB     . LEU A 1 482 ? 112.487 103.884 143.260 1.00 89.42  ? 473 LEU A CB     1 
ATOM   5797 C CG     . LEU A 1 482 ? 113.178 105.005 144.034 1.00 89.42  ? 473 LEU A CG     1 
ATOM   5798 C CD1    . LEU A 1 482 ? 112.542 106.347 143.722 1.00 89.42  ? 473 LEU A CD1    1 
ATOM   5799 C CD2    . LEU A 1 482 ? 113.121 104.720 145.525 1.00 89.42  ? 473 LEU A CD2    1 
ATOM   5800 H H      . LEU A 1 482 ? 114.185 102.713 141.405 1.00 89.42  ? 473 LEU A H      1 
ATOM   5801 H HA     . LEU A 1 482 ? 113.641 102.374 144.037 1.00 89.42  ? 473 LEU A HA     1 
ATOM   5802 H HB2    . LEU A 1 482 ? 112.308 104.211 142.365 1.00 89.42  ? 473 LEU A HB2    1 
ATOM   5803 H HB3    . LEU A 1 482 ? 111.650 103.687 143.710 1.00 89.42  ? 473 LEU A HB3    1 
ATOM   5804 H HG     . LEU A 1 482 ? 114.111 105.044 143.772 1.00 89.42  ? 473 LEU A HG     1 
ATOM   5805 H HD11   . LEU A 1 482 ? 112.974 107.032 144.255 1.00 89.42  ? 473 LEU A HD11   1 
ATOM   5806 H HD12   . LEU A 1 482 ? 112.658 106.539 142.778 1.00 89.42  ? 473 LEU A HD12   1 
ATOM   5807 H HD13   . LEU A 1 482 ? 111.597 106.306 143.938 1.00 89.42  ? 473 LEU A HD13   1 
ATOM   5808 H HD21   . LEU A 1 482 ? 112.193 104.626 145.792 1.00 89.42  ? 473 LEU A HD21   1 
ATOM   5809 H HD22   . LEU A 1 482 ? 113.530 105.458 146.003 1.00 89.42  ? 473 LEU A HD22   1 
ATOM   5810 H HD23   . LEU A 1 482 ? 113.603 103.899 145.709 1.00 89.42  ? 473 LEU A HD23   1 
ATOM   5811 N N      . GLU A 1 483 ? 111.806 100.775 143.686 1.00 94.77  ? 474 GLU A N      1 
ATOM   5812 C CA     . GLU A 1 483 ? 110.891 99.675  143.426 1.00 94.77  ? 474 GLU A CA     1 
ATOM   5813 C C      . GLU A 1 483 ? 109.845 99.648  144.530 1.00 94.77  ? 474 GLU A C      1 
ATOM   5814 O O      . GLU A 1 483 ? 110.041 100.210 145.611 1.00 94.77  ? 474 GLU A O      1 
ATOM   5815 C CB     . GLU A 1 483 ? 111.632 98.336  143.339 1.00 94.77  ? 474 GLU A CB     1 
ATOM   5816 C CG     . GLU A 1 483 ? 112.753 98.327  142.311 1.00 94.77  ? 474 GLU A CG     1 
ATOM   5817 C CD     . GLU A 1 483 ? 113.383 96.964  142.142 1.00 94.77  ? 474 GLU A CD     1 
ATOM   5818 O OE1    . GLU A 1 483 ? 112.735 95.961  142.505 1.00 94.77  ? 474 GLU A OE1    1 
ATOM   5819 O OE2    . GLU A 1 483 ? 114.527 96.895  141.648 1.00 94.77  ? 474 GLU A OE2    1 
ATOM   5820 H H      . GLU A 1 483 ? 111.918 100.942 144.522 1.00 94.77  ? 474 GLU A H      1 
ATOM   5821 H HA     . GLU A 1 483 ? 110.439 99.826  142.582 1.00 94.77  ? 474 GLU A HA     1 
ATOM   5822 H HB2    . GLU A 1 483 ? 112.021 98.136  144.205 1.00 94.77  ? 474 GLU A HB2    1 
ATOM   5823 H HB3    . GLU A 1 483 ? 110.999 97.643  143.094 1.00 94.77  ? 474 GLU A HB3    1 
ATOM   5824 H HG2    . GLU A 1 483 ? 112.397 98.603  141.452 1.00 94.77  ? 474 GLU A HG2    1 
ATOM   5825 H HG3    . GLU A 1 483 ? 113.448 98.941  142.595 1.00 94.77  ? 474 GLU A HG3    1 
ATOM   5826 N N      . GLU A 1 484 ? 108.729 98.984  144.246 1.00 100.31 ? 475 GLU A N      1 
ATOM   5827 C CA     . GLU A 1 484 ? 107.567 99.009  145.122 1.00 100.31 ? 475 GLU A CA     1 
ATOM   5828 C C      . GLU A 1 484 ? 107.620 97.967  146.231 1.00 100.31 ? 475 GLU A C      1 
ATOM   5829 O O      . GLU A 1 484 ? 106.681 97.893  147.030 1.00 100.31 ? 475 GLU A O      1 
ATOM   5830 C CB     . GLU A 1 484 ? 106.289 98.813  144.300 1.00 100.31 ? 475 GLU A CB     1 
ATOM   5831 C CG     . GLU A 1 484 ? 105.884 100.038 143.504 1.00 100.31 ? 475 GLU A CG     1 
ATOM   5832 C CD     . GLU A 1 484 ? 105.472 101.191 144.395 1.00 100.31 ? 475 GLU A CD     1 
ATOM   5833 O OE1    . GLU A 1 484 ? 104.970 100.932 145.509 1.00 100.31 ? 475 GLU A OE1    1 
ATOM   5834 O OE2    . GLU A 1 484 ? 105.657 102.356 143.986 1.00 100.31 ? 475 GLU A OE2    1 
ATOM   5835 H H      . GLU A 1 484 ? 108.621 98.504  143.541 1.00 100.31 ? 475 GLU A H      1 
ATOM   5836 H HA     . GLU A 1 484 ? 107.518 99.881  145.544 1.00 100.31 ? 475 GLU A HA     1 
ATOM   5837 H HB2    . GLU A 1 484 ? 106.428 98.085  143.674 1.00 100.31 ? 475 GLU A HB2    1 
ATOM   5838 H HB3    . GLU A 1 484 ? 105.560 98.594  144.901 1.00 100.31 ? 475 GLU A HB3    1 
ATOM   5839 H HG2    . GLU A 1 484 ? 106.635 100.327 142.963 1.00 100.31 ? 475 GLU A HG2    1 
ATOM   5840 H HG3    . GLU A 1 484 ? 105.131 99.812  142.936 1.00 100.31 ? 475 GLU A HG3    1 
ATOM   5841 N N      . GLU A 1 485 ? 108.686 97.169  146.311 1.00 97.38  ? 476 GLU A N      1 
ATOM   5842 C CA     . GLU A 1 485 ? 108.784 96.190  147.387 1.00 97.38  ? 476 GLU A CA     1 
ATOM   5843 C C      . GLU A 1 485 ? 108.791 96.857  148.756 1.00 97.38  ? 476 GLU A C      1 
ATOM   5844 O O      . GLU A 1 485 ? 108.502 96.197  149.760 1.00 97.38  ? 476 GLU A O      1 
ATOM   5845 C CB     . GLU A 1 485 ? 110.040 95.336  147.203 1.00 97.38  ? 476 GLU A CB     1 
ATOM   5846 C CG     . GLU A 1 485 ? 110.139 94.142  148.148 1.00 97.38  ? 476 GLU A CG     1 
ATOM   5847 C CD     . GLU A 1 485 ? 110.835 94.471  149.456 1.00 97.38  ? 476 GLU A CD     1 
ATOM   5848 O OE1    . GLU A 1 485 ? 111.679 95.392  149.470 1.00 97.38  ? 476 GLU A OE1    1 
ATOM   5849 O OE2    . GLU A 1 485 ? 110.539 93.806  150.471 1.00 97.38  ? 476 GLU A OE2    1 
ATOM   5850 H H      . GLU A 1 485 ? 109.351 97.174  145.766 1.00 97.38  ? 476 GLU A H      1 
ATOM   5851 H HA     . GLU A 1 485 ? 108.014 95.601  147.347 1.00 97.38  ? 476 GLU A HA     1 
ATOM   5852 H HB2    . GLU A 1 485 ? 110.047 94.992  146.296 1.00 97.38  ? 476 GLU A HB2    1 
ATOM   5853 H HB3    . GLU A 1 485 ? 110.819 95.896  147.342 1.00 97.38  ? 476 GLU A HB3    1 
ATOM   5854 H HG2    . GLU A 1 485 ? 109.244 93.832  148.357 1.00 97.38  ? 476 GLU A HG2    1 
ATOM   5855 H HG3    . GLU A 1 485 ? 110.642 93.437  147.712 1.00 97.38  ? 476 GLU A HG3    1 
ATOM   5856 N N      . LEU A 1 486 ? 109.106 98.151  148.816 1.00 96.27  ? 477 LEU A N      1 
ATOM   5857 C CA     . LEU A 1 486 ? 109.070 98.911  150.059 1.00 96.27  ? 477 LEU A CA     1 
ATOM   5858 C C      . LEU A 1 486 ? 107.680 99.436  150.394 1.00 96.27  ? 477 LEU A C      1 
ATOM   5859 O O      . LEU A 1 486 ? 107.498 100.015 151.471 1.00 96.27  ? 477 LEU A O      1 
ATOM   5860 C CB     . LEU A 1 486 ? 110.056 100.082 149.971 1.00 96.27  ? 477 LEU A CB     1 
ATOM   5861 C CG     . LEU A 1 486 ? 110.134 101.054 151.150 1.00 96.27  ? 477 LEU A CG     1 
ATOM   5862 C CD1    . LEU A 1 486 ? 110.421 100.315 152.446 1.00 96.27  ? 477 LEU A CD1    1 
ATOM   5863 C CD2    . LEU A 1 486 ? 111.196 102.107 150.884 1.00 96.27  ? 477 LEU A CD2    1 
ATOM   5864 H H      . LEU A 1 486 ? 109.349 98.618  148.136 1.00 96.27  ? 477 LEU A H      1 
ATOM   5865 H HA     . LEU A 1 486 ? 109.354 98.334  150.785 1.00 96.27  ? 477 LEU A HA     1 
ATOM   5866 H HB2    . LEU A 1 486 ? 110.946 99.714  149.852 1.00 96.27  ? 477 LEU A HB2    1 
ATOM   5867 H HB3    . LEU A 1 486 ? 109.826 100.606 149.189 1.00 96.27  ? 477 LEU A HB3    1 
ATOM   5868 H HG     . LEU A 1 486 ? 109.285 101.512 151.244 1.00 96.27  ? 477 LEU A HG     1 
ATOM   5869 H HD11   . LEU A 1 486 ? 111.277 99.864  152.369 1.00 96.27  ? 477 LEU A HD11   1 
ATOM   5870 H HD12   . LEU A 1 486 ? 109.719 99.666  152.604 1.00 96.27  ? 477 LEU A HD12   1 
ATOM   5871 H HD13   . LEU A 1 486 ? 110.450 100.956 153.174 1.00 96.27  ? 477 LEU A HD13   1 
ATOM   5872 H HD21   . LEU A 1 486 ? 110.956 102.601 150.084 1.00 96.27  ? 477 LEU A HD21   1 
ATOM   5873 H HD22   . LEU A 1 486 ? 112.052 101.668 150.758 1.00 96.27  ? 477 LEU A HD22   1 
ATOM   5874 H HD23   . LEU A 1 486 ? 111.241 102.709 151.643 1.00 96.27  ? 477 LEU A HD23   1 
ATOM   5875 N N      . ARG A 1 487 ? 106.696 99.239  149.513 1.00 97.92  ? 478 ARG A N      1 
ATOM   5876 C CA     . ARG A 1 487 ? 105.378 99.829  149.721 1.00 97.92  ? 478 ARG A CA     1 
ATOM   5877 C C      . ARG A 1 487 ? 104.726 99.355  151.014 1.00 97.92  ? 478 ARG A C      1 
ATOM   5878 O O      . ARG A 1 487 ? 103.877 100.066 151.563 1.00 97.92  ? 478 ARG A O      1 
ATOM   5879 C CB     . ARG A 1 487 ? 104.476 99.507  148.527 1.00 97.92  ? 478 ARG A CB     1 
ATOM   5880 C CG     . ARG A 1 487 ? 103.126 100.210 148.538 1.00 97.92  ? 478 ARG A CG     1 
ATOM   5881 C CD     . ARG A 1 487 ? 103.270 101.724 148.588 1.00 97.92  ? 478 ARG A CD     1 
ATOM   5882 N NE     . ARG A 1 487 ? 104.134 102.240 147.533 1.00 97.92  ? 478 ARG A NE     1 
ATOM   5883 C CZ     . ARG A 1 487 ? 104.461 103.517 147.391 1.00 97.92  ? 478 ARG A CZ     1 
ATOM   5884 N NH1    . ARG A 1 487 ? 104.017 104.443 148.225 1.00 97.92  ? 478 ARG A NH1    1 
ATOM   5885 N NH2    . ARG A 1 487 ? 105.255 103.876 146.386 1.00 97.92  ? 478 ARG A NH2    1 
ATOM   5886 H H      . ARG A 1 487 ? 106.766 98.773  148.794 1.00 97.92  ? 478 ARG A H      1 
ATOM   5887 H HA     . ARG A 1 487 ? 105.478 100.791 149.776 1.00 97.92  ? 478 ARG A HA     1 
ATOM   5888 H HB2    . ARG A 1 487 ? 104.937 99.764  147.713 1.00 97.92  ? 478 ARG A HB2    1 
ATOM   5889 H HB3    . ARG A 1 487 ? 104.308 98.552  148.517 1.00 97.92  ? 478 ARG A HB3    1 
ATOM   5890 H HG2    . ARG A 1 487 ? 102.642 99.979  147.730 1.00 97.92  ? 478 ARG A HG2    1 
ATOM   5891 H HG3    . ARG A 1 487 ? 102.624 99.927  149.319 1.00 97.92  ? 478 ARG A HG3    1 
ATOM   5892 H HD2    . ARG A 1 487 ? 102.394 102.126 148.478 1.00 97.92  ? 478 ARG A HD2    1 
ATOM   5893 H HD3    . ARG A 1 487 ? 103.647 101.983 149.443 1.00 97.92  ? 478 ARG A HD3    1 
ATOM   5894 H HE     . ARG A 1 487 ? 104.392 101.691 146.923 1.00 97.92  ? 478 ARG A HE     1 
ATOM   5895 H HH11   . ARG A 1 487 ? 103.503 104.225 148.879 1.00 97.92  ? 478 ARG A HH11   1 
ATOM   5896 H HH12   . ARG A 1 487 ? 104.243 105.265 148.114 1.00 97.92  ? 478 ARG A HH12   1 
ATOM   5897 H HH21   . ARG A 1 487 ? 105.550 103.283 145.838 1.00 97.92  ? 478 ARG A HH21   1 
ATOM   5898 H HH22   . ARG A 1 487 ? 105.474 104.702 146.285 1.00 97.92  ? 478 ARG A HH22   1 
ATOM   5899 N N      . ARG A 1 488 ? 105.105 98.179  151.516 1.00 103.99 ? 479 ARG A N      1 
ATOM   5900 C CA     . ARG A 1 488 ? 104.528 97.669  152.756 1.00 103.99 ? 479 ARG A CA     1 
ATOM   5901 C C      . ARG A 1 488 ? 104.875 98.544  153.956 1.00 103.99 ? 479 ARG A C      1 
ATOM   5902 O O      . ARG A 1 488 ? 104.188 98.474  154.980 1.00 103.99 ? 479 ARG A O      1 
ATOM   5903 C CB     . ARG A 1 488 ? 105.019 96.235  152.991 1.00 103.99 ? 479 ARG A CB     1 
ATOM   5904 C CG     . ARG A 1 488 ? 104.111 95.353  153.850 1.00 103.99 ? 479 ARG A CG     1 
ATOM   5905 C CD     . ARG A 1 488 ? 104.191 95.693  155.331 1.00 103.99 ? 479 ARG A CD     1 
ATOM   5906 N NE     . ARG A 1 488 ? 103.912 94.542  156.181 1.00 103.99 ? 479 ARG A NE     1 
ATOM   5907 C CZ     . ARG A 1 488 ? 103.894 94.580  157.507 1.00 103.99 ? 479 ARG A CZ     1 
ATOM   5908 N NH1    . ARG A 1 488 ? 104.137 95.698  158.171 1.00 103.99 ? 479 ARG A NH1    1 
ATOM   5909 N NH2    . ARG A 1 488 ? 103.625 93.467  158.185 1.00 103.99 ? 479 ARG A NH2    1 
ATOM   5910 H H      . ARG A 1 488 ? 105.692 97.661  151.159 1.00 103.99 ? 479 ARG A H      1 
ATOM   5911 H HA     . ARG A 1 488 ? 103.563 97.646  152.669 1.00 103.99 ? 479 ARG A HA     1 
ATOM   5912 H HB2    . ARG A 1 488 ? 105.113 95.799  152.130 1.00 103.99 ? 479 ARG A HB2    1 
ATOM   5913 H HB3    . ARG A 1 488 ? 105.884 96.275  153.427 1.00 103.99 ? 479 ARG A HB3    1 
ATOM   5914 H HG2    . ARG A 1 488 ? 103.193 95.470  153.563 1.00 103.99 ? 479 ARG A HG2    1 
ATOM   5915 H HG3    . ARG A 1 488 ? 104.377 94.426  153.741 1.00 103.99 ? 479 ARG A HG3    1 
ATOM   5916 H HD2    . ARG A 1 488 ? 105.079 96.021  155.542 1.00 103.99 ? 479 ARG A HD2    1 
ATOM   5917 H HD3    . ARG A 1 488 ? 103.524 96.366  155.535 1.00 103.99 ? 479 ARG A HD3    1 
ATOM   5918 H HE     . ARG A 1 488 ? 103.854 93.771  155.804 1.00 103.99 ? 479 ARG A HE     1 
ATOM   5919 H HH11   . ARG A 1 488 ? 104.311 96.425  157.745 1.00 103.99 ? 479 ARG A HH11   1 
ATOM   5920 H HH12   . ARG A 1 488 ? 104.119 95.699  159.031 1.00 103.99 ? 479 ARG A HH12   1 
ATOM   5921 H HH21   . ARG A 1 488 ? 103.467 92.735  157.763 1.00 103.99 ? 479 ARG A HH21   1 
ATOM   5922 H HH22   . ARG A 1 488 ? 103.612 93.480  159.045 1.00 103.99 ? 479 ARG A HH22   1 
ATOM   5923 N N      . ARG A 1 489 ? 105.903 99.386  153.846 1.00 101.40 ? 480 ARG A N      1 
ATOM   5924 C CA     . ARG A 1 489 ? 106.506 100.019 155.013 1.00 101.40 ? 480 ARG A CA     1 
ATOM   5925 C C      . ARG A 1 489 ? 105.928 101.396 155.338 1.00 101.40 ? 480 ARG A C      1 
ATOM   5926 O O      . ARG A 1 489 ? 105.704 101.702 156.515 1.00 101.40 ? 480 ARG A O      1 
ATOM   5927 C CB     . ARG A 1 489 ? 108.018 100.141 154.799 1.00 101.40 ? 480 ARG A CB     1 
ATOM   5928 C CG     . ARG A 1 489 ? 108.836 100.260 156.074 1.00 101.40 ? 480 ARG A CG     1 
ATOM   5929 C CD     . ARG A 1 489 ? 108.849 98.954  156.854 1.00 101.40 ? 480 ARG A CD     1 
ATOM   5930 N NE     . ARG A 1 489 ? 109.900 98.933  157.863 1.00 101.40 ? 480 ARG A NE     1 
ATOM   5931 C CZ     . ARG A 1 489 ? 111.154 98.563  157.636 1.00 101.40 ? 480 ARG A CZ     1 
ATOM   5932 N NH1    . ARG A 1 489 ? 111.556 98.176  156.436 1.00 101.40 ? 480 ARG A NH1    1 
ATOM   5933 N NH2    . ARG A 1 489 ? 112.027 98.582  158.639 1.00 101.40 ? 480 ARG A NH2    1 
ATOM   5934 H H      . ARG A 1 489 ? 106.272 99.606  153.101 1.00 101.40 ? 480 ARG A H      1 
ATOM   5935 H HA     . ARG A 1 489 ? 106.359 99.449  155.785 1.00 101.40 ? 480 ARG A HA     1 
ATOM   5936 H HB2    . ARG A 1 489 ? 108.324 99.351  154.327 1.00 101.40 ? 480 ARG A HB2    1 
ATOM   5937 H HB3    . ARG A 1 489 ? 108.193 100.931 154.263 1.00 101.40 ? 480 ARG A HB3    1 
ATOM   5938 H HG2    . ARG A 1 489 ? 109.751 100.486 155.847 1.00 101.40 ? 480 ARG A HG2    1 
ATOM   5939 H HG3    . ARG A 1 489 ? 108.451 100.948 156.638 1.00 101.40 ? 480 ARG A HG3    1 
ATOM   5940 H HD2    . ARG A 1 489 ? 107.998 98.849  157.307 1.00 101.40 ? 480 ARG A HD2    1 
ATOM   5941 H HD3    . ARG A 1 489 ? 108.992 98.215  156.243 1.00 101.40 ? 480 ARG A HD3    1 
ATOM   5942 H HE     . ARG A 1 489 ? 109.709 99.235  158.646 1.00 101.40 ? 480 ARG A HE     1 
ATOM   5943 H HH11   . ARG A 1 489 ? 111.004 98.159  155.778 1.00 101.40 ? 480 ARG A HH11   1 
ATOM   5944 H HH12   . ARG A 1 489 ? 112.374 97.941  156.314 1.00 101.40 ? 480 ARG A HH12   1 
ATOM   5945 H HH21   . ARG A 1 489 ? 111.777 98.831  159.423 1.00 101.40 ? 480 ARG A HH21   1 
ATOM   5946 H HH22   . ARG A 1 489 ? 112.843 98.344  158.503 1.00 101.40 ? 480 ARG A HH22   1 
ATOM   5947 N N      . LEU A 1 490 ? 105.674 102.236 154.333 1.00 103.55 ? 481 LEU A N      1 
ATOM   5948 C CA     . LEU A 1 490 ? 105.472 103.665 154.555 1.00 103.55 ? 481 LEU A CA     1 
ATOM   5949 C C      . LEU A 1 490 ? 104.036 104.118 154.320 1.00 103.55 ? 481 LEU A C      1 
ATOM   5950 O O      . LEU A 1 490 ? 103.398 104.642 155.239 1.00 103.55 ? 481 LEU A O      1 
ATOM   5951 C CB     . LEU A 1 490 ? 106.430 104.453 153.646 1.00 103.55 ? 481 LEU A CB     1 
ATOM   5952 C CG     . LEU A 1 490 ? 106.834 105.864 154.083 1.00 103.55 ? 481 LEU A CG     1 
ATOM   5953 C CD1    . LEU A 1 490 ? 107.791 106.472 153.070 1.00 103.55 ? 481 LEU A CD1    1 
ATOM   5954 C CD2    . LEU A 1 490 ? 105.628 106.769 154.275 1.00 103.55 ? 481 LEU A CD2    1 
ATOM   5955 H H      . LEU A 1 490 ? 105.614 102.000 153.508 1.00 103.55 ? 481 LEU A H      1 
ATOM   5956 H HA     . LEU A 1 490 ? 105.700 103.874 155.475 1.00 103.55 ? 481 LEU A HA     1 
ATOM   5957 H HB2    . LEU A 1 490 ? 107.247 103.939 153.558 1.00 103.55 ? 481 LEU A HB2    1 
ATOM   5958 H HB3    . LEU A 1 490 ? 106.015 104.535 152.773 1.00 103.55 ? 481 LEU A HB3    1 
ATOM   5959 H HG     . LEU A 1 490 ? 107.299 105.808 154.932 1.00 103.55 ? 481 LEU A HG     1 
ATOM   5960 H HD11   . LEU A 1 490 ? 108.569 105.900 152.989 1.00 103.55 ? 481 LEU A HD11   1 
ATOM   5961 H HD12   . LEU A 1 490 ? 107.341 106.543 152.214 1.00 103.55 ? 481 LEU A HD12   1 
ATOM   5962 H HD13   . LEU A 1 490 ? 108.057 107.353 153.378 1.00 103.55 ? 481 LEU A HD13   1 
ATOM   5963 H HD21   . LEU A 1 490 ? 105.158 106.501 155.080 1.00 103.55 ? 481 LEU A HD21   1 
ATOM   5964 H HD22   . LEU A 1 490 ? 105.045 106.685 153.505 1.00 103.55 ? 481 LEU A HD22   1 
ATOM   5965 H HD23   . LEU A 1 490 ? 105.934 107.685 154.361 1.00 103.55 ? 481 LEU A HD23   1 
ATOM   5966 N N      . THR A 1 491 ? 103.500 103.929 153.112 1.00 104.30 ? 482 THR A N      1 
ATOM   5967 C CA     . THR A 1 491 ? 102.268 104.583 152.685 1.00 104.30 ? 482 THR A CA     1 
ATOM   5968 C C      . THR A 1 491 ? 101.060 103.652 152.720 1.00 104.30 ? 482 THR A C      1 
ATOM   5969 O O      . THR A 1 491 ? 100.202 103.723 151.833 1.00 104.30 ? 482 THR A O      1 
ATOM   5970 C CB     . THR A 1 491 ? 102.434 105.154 151.277 1.00 104.30 ? 482 THR A CB     1 
ATOM   5971 O OG1    . THR A 1 491 ? 102.629 104.082 150.344 1.00 104.30 ? 482 THR A OG1    1 
ATOM   5972 C CG2    . THR A 1 491 ? 103.626 106.100 151.213 1.00 104.30 ? 482 THR A CG2    1 
ATOM   5973 H H      . THR A 1 491 ? 103.841 103.417 152.512 1.00 104.30 ? 482 THR A H      1 
ATOM   5974 H HA     . THR A 1 491 ? 102.086 105.326 153.282 1.00 104.30 ? 482 THR A HA     1 
ATOM   5975 H HB     . THR A 1 491 ? 101.638 105.653 151.036 1.00 104.30 ? 482 THR A HB     1 
ATOM   5976 H HG1    . THR A 1 491 ? 101.964 103.569 150.348 1.00 104.30 ? 482 THR A HG1    1 
ATOM   5977 H HG21   . THR A 1 491 ? 103.711 106.463 150.318 1.00 104.30 ? 482 THR A HG21   1 
ATOM   5978 H HG22   . THR A 1 491 ? 103.501 106.831 151.838 1.00 104.30 ? 482 THR A HG22   1 
ATOM   5979 H HG23   . THR A 1 491 ? 104.442 105.626 151.438 1.00 104.30 ? 482 THR A HG23   1 
ATOM   5980 N N      . GLU A 1 492 ? 100.969 102.784 153.721 1.00 105.95 ? 483 GLU A N      1 
ATOM   5981 C CA     . GLU A 1 492 ? 99.840  101.866 153.816 1.00 105.95 ? 483 GLU A CA     1 
ATOM   5982 C C      . GLU A 1 492 ? 99.806  101.173 155.173 1.00 105.95 ? 483 GLU A C      1 
ATOM   5983 O O      . GLU A 1 492 ? 100.831 101.029 155.838 1.00 105.95 ? 483 GLU A O      1 
ATOM   5984 C CB     . GLU A 1 492 ? 99.907  100.826 152.697 1.00 105.95 ? 483 GLU A CB     1 
ATOM   5985 C CG     . GLU A 1 492 ? 98.625  100.039 152.500 1.00 105.95 ? 483 GLU A CG     1 
ATOM   5986 C CD     . GLU A 1 492 ? 98.728  99.046  151.359 1.00 105.95 ? 483 GLU A CD     1 
ATOM   5987 O OE1    . GLU A 1 492 ? 99.844  98.865  150.828 1.00 105.95 ? 483 GLU A OE1    1 
ATOM   5988 O OE2    . GLU A 1 492 ? 97.694  98.449  150.992 1.00 105.95 ? 483 GLU A OE2    1 
ATOM   5989 H H      . GLU A 1 492 ? 101.545 102.707 154.355 1.00 105.95 ? 483 GLU A H      1 
ATOM   5990 H HA     . GLU A 1 492 ? 99.015  102.366 153.712 1.00 105.95 ? 483 GLU A HA     1 
ATOM   5991 H HB2    . GLU A 1 492 ? 100.109 101.272 151.860 1.00 105.95 ? 483 GLU A HB2    1 
ATOM   5992 H HB3    . GLU A 1 492 ? 100.611 100.192 152.904 1.00 105.95 ? 483 GLU A HB3    1 
ATOM   5993 H HG2    . GLU A 1 492 ? 98.426  99.546  153.311 1.00 105.95 ? 483 GLU A HG2    1 
ATOM   5994 H HG3    . GLU A 1 492 ? 97.903  100.655 152.298 1.00 105.95 ? 483 GLU A HG3    1 
HETATM 5995 C C1     . T44 B 2 .   ? 118.499 116.903 113.763 1.00 41.52  ? 600 T44 A C1     1 
HETATM 5996 C C2     . T44 B 2 .   ? 119.046 115.642 113.574 1.00 41.72  ? 600 T44 A C2     1 
HETATM 5997 C C3     . T44 B 2 .   ? 118.674 114.580 114.383 1.00 42.66  ? 600 T44 A C3     1 
HETATM 5998 C C4     . T44 B 2 .   ? 117.738 114.767 115.390 1.00 43.21  ? 600 T44 A C4     1 
HETATM 5999 C C5     . T44 B 2 .   ? 117.201 116.022 115.577 1.00 40.25  ? 600 T44 A C5     1 
HETATM 6000 C C6     . T44 B 2 .   ? 117.567 117.087 114.774 1.00 39.57  ? 600 T44 A C6     1 
HETATM 6001 C C7     . T44 B 2 .   ? 118.909 118.071 112.871 1.00 37.77  ? 600 T44 A C7     1 
HETATM 6002 C CA     . T44 B 2 .   ? 119.890 118.960 113.632 1.00 38.63  ? 600 T44 A CA     1 
HETATM 6003 C C      . T44 B 2 .   ? 121.226 119.071 112.894 1.00 38.54  ? 600 T44 A C      1 
HETATM 6004 C "C1'"  . T44 B 2 .   ? 116.619 112.732 115.570 1.00 50.57  ? 600 T44 A "C1'"  1 
HETATM 6005 C "C2'"  . T44 B 2 .   ? 115.763 113.028 114.515 1.00 52.52  ? 600 T44 A "C2'"  1 
HETATM 6006 C "C3'"  . T44 B 2 .   ? 115.080 111.999 113.878 1.00 56.82  ? 600 T44 A "C3'"  1 
HETATM 6007 C "C4'"  . T44 B 2 .   ? 115.248 110.688 114.284 1.00 57.90  ? 600 T44 A "C4'"  1 
HETATM 6008 C "C5'"  . T44 B 2 .   ? 116.101 110.402 115.331 1.00 56.66  ? 600 T44 A "C5'"  1 
HETATM 6009 C "C6'"  . T44 B 2 .   ? 116.784 111.415 115.973 1.00 52.81  ? 600 T44 A "C6'"  1 
HETATM 6010 N N      . T44 B 2 .   ? 119.316 120.286 113.766 1.00 38.42  ? 600 T44 A N      1 
HETATM 6011 O O4     . T44 B 2 .   ? 117.333 113.731 116.242 1.00 47.13  ? 600 T44 A O4     1 
HETATM 6012 O "O4'"  . T44 B 2 .   ? 114.553 109.658 113.637 1.00 61.53  ? 600 T44 A "O4'"  1 
HETATM 6013 O O      . T44 B 2 .   ? 121.957 120.078 113.085 1.00 29.90  ? 600 T44 A O      1 
HETATM 6014 O OXT    . T44 B 2 .   ? 121.606 118.168 112.104 1.00 41.95  ? 600 T44 A OXT    1 
HETATM 6015 I I3     . T44 B 2 .   ? 119.565 112.697 114.022 1.00 23.98  ? 600 T44 A I3     1 
HETATM 6016 I "I3'"  . T44 B 2 .   ? 113.773 112.426 112.278 1.00 61.88  ? 600 T44 A "I3'"  1 
HETATM 6017 I I5     . T44 B 2 .   ? 115.786 116.320 117.111 1.00 24.16  ? 600 T44 A I5     1 
HETATM 6018 I "I5'"  . T44 B 2 .   ? 116.364 108.406 115.962 1.00 63.16  ? 600 T44 A "I5'"  1 
HETATM 6019 H H1     . T44 B 2 .   ? 119.774 115.487 112.787 1.00 41.72  ? 600 T44 A H1     1 
HETATM 6020 H H6     . T44 B 2 .   ? 117.128 118.064 114.935 1.00 39.57  ? 600 T44 A H6     1 
HETATM 6021 H H71    . T44 B 2 .   ? 118.028 118.649 112.612 1.00 37.77  ? 600 T44 A H71    1 
HETATM 6022 H H72    . T44 B 2 .   ? 119.366 117.691 111.964 1.00 37.77  ? 600 T44 A H72    1 
HETATM 6023 H HA     . T44 B 2 .   ? 120.060 118.543 114.617 1.00 38.63  ? 600 T44 A HA     1 
HETATM 6024 H "H2'"  . T44 B 2 .   ? 115.624 114.051 114.189 1.00 52.52  ? 600 T44 A "H2'"  1 
HETATM 6025 H "H6'"  . T44 B 2 .   ? 117.452 111.182 116.793 1.00 52.81  ? 600 T44 A "H6'"  1 
HETATM 6026 H H      . T44 B 2 .   ? 120.026 120.930 114.066 1.00 38.42  ? 600 T44 A H      1 
HETATM 6027 H H2     . T44 B 2 .   ? 118.576 120.263 114.446 1.00 38.42  ? 600 T44 A H2     1 
HETATM 6028 H "HO4'" . T44 B 2 .   ? 115.158 108.975 113.394 1.00 61.53  ? 600 T44 A "HO4'" 1 
HETATM 6029 H H83    . T44 B 2 .   ? 118.948 120.583 112.879 1.00 38.42  ? 600 T44 A H83    1 
# 
