data_9GR4
# 
_entry.id   9GR4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GR4         pdb_00009gr4 10.2210/pdb9gr4/pdb 
WWPDB D_1292141640 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-05 ? 
2 'Structure model' 1 1 2025-03-12 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GR4 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        . 
_pdbx_database_related.db_id          8C9Y 
_pdbx_database_related.content_type   unspecified 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              peter.crowley@universityofgalway.ie 
_pdbx_contact_author.name_first         Peter 
_pdbx_contact_author.name_last          Crowley 
_pdbx_contact_author.name_mi            B 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-5365-0096 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Mockler, N.M.' 1 0000-0003-3392-9564 
'Ramberg, K.O.' 2 0000-0002-3991-4809 
'Flood, R.J.'   3 0000-0002-0848-4236 
'Crowley, P.B.' 4 0000-0002-5365-0096 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biochemistry 
_citation.journal_id_ASTM           BICHAW 
_citation.journal_id_CSD            0033 
_citation.journal_id_ISSN           0006-2960 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            64 
_citation.language                  ? 
_citation.page_first                1092 
_citation.page_last                 1098 
_citation.title                     'N-Terminal Protein Binding and Disorder-to-Order Transition by a Synthetic Receptor.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.biochem.4c00729 
_citation.pdbx_database_id_PubMed   39977527 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Mockler, N.M.' 1 ? 
primary 'Ramberg, K.O.' 2 ? 
primary 'Flood, R.J.'   3 ? 
primary 'Crowley, P.B.' 4 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Fucose-binding lectin protein' 9977.938 6   ? 'Met-1, Lys0, S1A' ? 'Met-Lys-Ala N-terminal extension' 
2 non-polymer syn beta-D-fructopyranose 180.156  12  ? ?                  ? ?                                  
3 non-polymer syn 
;25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid
;
744.741  3   ? ?                  ? ?                                  
4 water       nat water 18.015   796 ? ?                  ? ?                                  
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKASVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDG
NGWTKGAYTATN
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKASVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDG
NGWTKGAYTATN
;
_entity_poly.pdbx_strand_id                 B,C,E,F,D,A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 beta-D-fructopyranose BDF 
3 
;25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid
;
T3Y 
4 water HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1  MET n 
1 2  LYS n 
1 3  ALA n 
1 4  SER n 
1 5  VAL n 
1 6  GLN n 
1 7  THR n 
1 8  ALA n 
1 9  ALA n 
1 10 THR n 
1 11 SER n 
1 12 TRP n 
1 13 GLY n 
1 14 THR n 
1 15 VAL n 
1 16 PRO n 
1 17 SER n 
1 18 ILE n 
1 19 ARG n 
1 20 VAL n 
1 21 TYR n 
1 22 THR n 
1 23 ALA n 
1 24 ASN n 
1 25 ASN n 
1 26 GLY n 
1 27 LYS n 
1 28 ILE n 
1 29 THR n 
1 30 GLU n 
1 31 ARG n 
1 32 CYS n 
1 33 TRP n 
1 34 ASP n 
1 35 GLY n 
1 36 LYS n 
1 37 GLY n 
1 38 TRP n 
1 39 TYR n 
1 40 THR n 
1 41 GLY n 
1 42 ALA n 
1 43 PHE n 
1 44 ASN n 
1 45 GLU n 
1 46 PRO n 
1 47 GLY n 
1 48 ASP n 
1 49 ASN n 
1 50 VAL n 
1 51 SER n 
1 52 VAL n 
1 53 THR n 
1 54 SER n 
1 55 TRP n 
1 56 LEU n 
1 57 VAL n 
1 58 GLY n 
1 59 SER n 
1 60 ALA n 
1 61 ILE n 
1 62 HIS n 
1 63 ILE n 
1 64 ARG n 
1 65 VAL n 
1 66 TYR n 
1 67 ALA n 
1 68 SER n 
1 69 THR n 
1 70 GLY n 
1 71 THR n 
1 72 THR n 
1 73 THR n 
1 74 THR n 
1 75 GLU n 
1 76 TRP n 
1 77 CYS n 
1 78 TRP n 
1 79 ASP n 
1 80 GLY n 
1 81 ASN n 
1 82 GLY n 
1 83 TRP n 
1 84 THR n 
1 85 LYS n 
1 86 GLY n 
1 87 ALA n 
1 88 TYR n 
1 89 THR n 
1 90 ALA n 
1 91 THR n 
1 92 ASN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   92 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'E7Z57_08365, HF909_06975, LBW55_09125, RUN39_v1_50103' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Ralstonia solanacearum' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     305 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE ?                                                              'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE ?                                                              'C6 H15 N4 O2 1' 
175.209 
ASN 'L-peptide linking'          y ASPARAGINE ?                                                              'C4 H8 N2 O3'    
132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID' ?                                                              'C4 H7 N O4'     
133.103 
BDF 'D-saccharide, beta linking' . beta-D-fructopyranose 'beta-D-fructose; D-fructose; fructose'                        
'C6 H12 O6'      180.156 
CYS 'L-peptide linking'          y CYSTEINE ?                                                              'C3 H7 N O2 S'   
121.158 
GLN 'L-peptide linking'          y GLUTAMINE ?                                                              'C5 H10 N2 O3'   
146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID' ?                                                              'C5 H9 N O4'     
147.129 
GLY 'peptide linking'            y GLYCINE ?                                                              'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE ?                                                              'C6 H10 N3 O2 1' 
156.162 
HOH non-polymer                  . WATER ?                                                              'H2 O'           18.015  
ILE 'L-peptide linking'          y ISOLEUCINE ?                                                              'C6 H13 N O2'    
131.173 
LEU 'L-peptide linking'          y LEUCINE ?                                                              'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE ?                                                              'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE ?                                                              'C5 H11 N O2 S'  
149.211 
PHE 'L-peptide linking'          y PHENYLALANINE ?                                                              'C9 H11 N O2'    
165.189 
PRO 'L-peptide linking'          y PROLINE ?                                                              'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE ?                                                              'C3 H7 N O3'     105.093 
T3Y non-polymer                  . 
;25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid
;
'5,11,17,23-tetra-sulphonato-calix[4]arene-25,26,27,28-tetrol' 'C28 H24 O16 S4' 744.741 
THR 'L-peptide linking'          y THREONINE ?                                                              'C4 H9 N O3'     
119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN ?                                                              'C11 H12 N2 O2'  
204.225 
TYR 'L-peptide linking'          y TYROSINE ?                                                              'C9 H11 N O3'    
181.189 
VAL 'L-peptide linking'          y VALINE ?                                                              'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BDF 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DFrupb             
BDF 'COMMON NAME'                         GMML     1.0 b-D-fructopyranose 
BDF 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Frup           
BDF 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Fru                
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1  MET 1  -1 -1 MET MET B . n 
A 1 2  LYS 2  0  0  LYS LYS B . n 
A 1 3  ALA 3  1  1  ALA ALA B . n 
A 1 4  SER 4  2  2  SER SER B . n 
A 1 5  VAL 5  3  3  VAL VAL B . n 
A 1 6  GLN 6  4  4  GLN GLN B . n 
A 1 7  THR 7  5  5  THR THR B . n 
A 1 8  ALA 8  6  6  ALA ALA B . n 
A 1 9  ALA 9  7  7  ALA ALA B . n 
A 1 10 THR 10 8  8  THR THR B . n 
A 1 11 SER 11 9  9  SER SER B . n 
A 1 12 TRP 12 10 10 TRP TRP B . n 
A 1 13 GLY 13 11 11 GLY GLY B . n 
A 1 14 THR 14 12 12 THR THR B . n 
A 1 15 VAL 15 13 13 VAL VAL B . n 
A 1 16 PRO 16 14 14 PRO PRO B . n 
A 1 17 SER 17 15 15 SER SER B . n 
A 1 18 ILE 18 16 16 ILE ILE B . n 
A 1 19 ARG 19 17 17 ARG ARG B . n 
A 1 20 VAL 20 18 18 VAL VAL B . n 
A 1 21 TYR 21 19 19 TYR TYR B . n 
A 1 22 THR 22 20 20 THR THR B . n 
A 1 23 ALA 23 21 21 ALA ALA B . n 
A 1 24 ASN 24 22 22 ASN ASN B . n 
A 1 25 ASN 25 23 23 ASN ASN B . n 
A 1 26 GLY 26 24 24 GLY GLY B . n 
A 1 27 LYS 27 25 25 LYS LYS B . n 
A 1 28 ILE 28 26 26 ILE ILE B . n 
A 1 29 THR 29 27 27 THR THR B . n 
A 1 30 GLU 30 28 28 GLU GLU B . n 
A 1 31 ARG 31 29 29 ARG ARG B . n 
A 1 32 CYS 32 30 30 CYS CYS B . n 
A 1 33 TRP 33 31 31 TRP TRP B . n 
A 1 34 ASP 34 32 32 ASP ASP B . n 
A 1 35 GLY 35 33 33 GLY GLY B . n 
A 1 36 LYS 36 34 34 LYS LYS B . n 
A 1 37 GLY 37 35 35 GLY GLY B . n 
A 1 38 TRP 38 36 36 TRP TRP B . n 
A 1 39 TYR 39 37 37 TYR TYR B . n 
A 1 40 THR 40 38 38 THR THR B . n 
A 1 41 GLY 41 39 39 GLY GLY B . n 
A 1 42 ALA 42 40 40 ALA ALA B . n 
A 1 43 PHE 43 41 41 PHE PHE B . n 
A 1 44 ASN 44 42 42 ASN ASN B . n 
A 1 45 GLU 45 43 43 GLU GLU B . n 
A 1 46 PRO 46 44 44 PRO PRO B . n 
A 1 47 GLY 47 45 45 GLY GLY B . n 
A 1 48 ASP 48 46 46 ASP ASP B . n 
A 1 49 ASN 49 47 47 ASN ASN B . n 
A 1 50 VAL 50 48 48 VAL VAL B . n 
A 1 51 SER 51 49 49 SER SER B . n 
A 1 52 VAL 52 50 50 VAL VAL B . n 
A 1 53 THR 53 51 51 THR THR B . n 
A 1 54 SER 54 52 52 SER SER B . n 
A 1 55 TRP 55 53 53 TRP TRP B . n 
A 1 56 LEU 56 54 54 LEU LEU B . n 
A 1 57 VAL 57 55 55 VAL VAL B . n 
A 1 58 GLY 58 56 56 GLY GLY B . n 
A 1 59 SER 59 57 57 SER SER B . n 
A 1 60 ALA 60 58 58 ALA ALA B . n 
A 1 61 ILE 61 59 59 ILE ILE B . n 
A 1 62 HIS 62 60 60 HIS HIS B . n 
A 1 63 ILE 63 61 61 ILE ILE B . n 
A 1 64 ARG 64 62 62 ARG ARG B . n 
A 1 65 VAL 65 63 63 VAL VAL B . n 
A 1 66 TYR 66 64 64 TYR TYR B . n 
A 1 67 ALA 67 65 65 ALA ALA B . n 
A 1 68 SER 68 66 66 SER SER B . n 
A 1 69 THR 69 67 67 THR THR B . n 
A 1 70 GLY 70 68 68 GLY GLY B . n 
A 1 71 THR 71 69 69 THR THR B . n 
A 1 72 THR 72 70 70 THR THR B . n 
A 1 73 THR 73 71 71 THR THR B . n 
A 1 74 THR 74 72 72 THR THR B . n 
A 1 75 GLU 75 73 73 GLU GLU B . n 
A 1 76 TRP 76 74 74 TRP TRP B . n 
A 1 77 CYS 77 75 75 CYS CYS B . n 
A 1 78 TRP 78 76 76 TRP TRP B . n 
A 1 79 ASP 79 77 77 ASP ASP B . n 
A 1 80 GLY 80 78 78 GLY GLY B . n 
A 1 81 ASN 81 79 79 ASN ASN B . n 
A 1 82 GLY 82 80 80 GLY GLY B . n 
A 1 83 TRP 83 81 81 TRP TRP B . n 
A 1 84 THR 84 82 82 THR THR B . n 
A 1 85 LYS 85 83 83 LYS LYS B . n 
A 1 86 GLY 86 84 84 GLY GLY B . n 
A 1 87 ALA 87 85 85 ALA ALA B . n 
A 1 88 TYR 88 86 86 TYR TYR B . n 
A 1 89 THR 89 87 87 THR THR B . n 
A 1 90 ALA 90 88 88 ALA ALA B . n 
A 1 91 THR 91 89 89 THR THR B . n 
A 1 92 ASN 92 90 90 ASN ASN B . n 
B 1 1  MET 1  -1 -1 MET MET C . n 
B 1 2  LYS 2  0  0  LYS LYS C . n 
B 1 3  ALA 3  1  1  ALA ALA C . n 
B 1 4  SER 4  2  2  SER SER C . n 
B 1 5  VAL 5  3  3  VAL VAL C . n 
B 1 6  GLN 6  4  4  GLN GLN C . n 
B 1 7  THR 7  5  5  THR THR C . n 
B 1 8  ALA 8  6  6  ALA ALA C . n 
B 1 9  ALA 9  7  7  ALA ALA C . n 
B 1 10 THR 10 8  8  THR THR C . n 
B 1 11 SER 11 9  9  SER SER C . n 
B 1 12 TRP 12 10 10 TRP TRP C . n 
B 1 13 GLY 13 11 11 GLY GLY C . n 
B 1 14 THR 14 12 12 THR THR C . n 
B 1 15 VAL 15 13 13 VAL VAL C . n 
B 1 16 PRO 16 14 14 PRO PRO C . n 
B 1 17 SER 17 15 15 SER SER C . n 
B 1 18 ILE 18 16 16 ILE ILE C . n 
B 1 19 ARG 19 17 17 ARG ARG C . n 
B 1 20 VAL 20 18 18 VAL VAL C . n 
B 1 21 TYR 21 19 19 TYR TYR C . n 
B 1 22 THR 22 20 20 THR THR C . n 
B 1 23 ALA 23 21 21 ALA ALA C . n 
B 1 24 ASN 24 22 22 ASN ASN C . n 
B 1 25 ASN 25 23 23 ASN ASN C . n 
B 1 26 GLY 26 24 24 GLY GLY C . n 
B 1 27 LYS 27 25 25 LYS LYS C . n 
B 1 28 ILE 28 26 26 ILE ILE C . n 
B 1 29 THR 29 27 27 THR THR C . n 
B 1 30 GLU 30 28 28 GLU GLU C . n 
B 1 31 ARG 31 29 29 ARG ARG C . n 
B 1 32 CYS 32 30 30 CYS CYS C . n 
B 1 33 TRP 33 31 31 TRP TRP C . n 
B 1 34 ASP 34 32 32 ASP ASP C . n 
B 1 35 GLY 35 33 33 GLY GLY C . n 
B 1 36 LYS 36 34 34 LYS LYS C . n 
B 1 37 GLY 37 35 35 GLY GLY C . n 
B 1 38 TRP 38 36 36 TRP TRP C . n 
B 1 39 TYR 39 37 37 TYR TYR C . n 
B 1 40 THR 40 38 38 THR THR C . n 
B 1 41 GLY 41 39 39 GLY GLY C . n 
B 1 42 ALA 42 40 40 ALA ALA C . n 
B 1 43 PHE 43 41 41 PHE PHE C . n 
B 1 44 ASN 44 42 42 ASN ASN C . n 
B 1 45 GLU 45 43 43 GLU GLU C . n 
B 1 46 PRO 46 44 44 PRO PRO C . n 
B 1 47 GLY 47 45 45 GLY GLY C . n 
B 1 48 ASP 48 46 46 ASP ASP C . n 
B 1 49 ASN 49 47 47 ASN ASN C . n 
B 1 50 VAL 50 48 48 VAL VAL C . n 
B 1 51 SER 51 49 49 SER SER C . n 
B 1 52 VAL 52 50 50 VAL VAL C . n 
B 1 53 THR 53 51 51 THR THR C . n 
B 1 54 SER 54 52 52 SER SER C . n 
B 1 55 TRP 55 53 53 TRP TRP C . n 
B 1 56 LEU 56 54 54 LEU LEU C . n 
B 1 57 VAL 57 55 55 VAL VAL C . n 
B 1 58 GLY 58 56 56 GLY GLY C . n 
B 1 59 SER 59 57 57 SER SER C . n 
B 1 60 ALA 60 58 58 ALA ALA C . n 
B 1 61 ILE 61 59 59 ILE ILE C . n 
B 1 62 HIS 62 60 60 HIS HIS C . n 
B 1 63 ILE 63 61 61 ILE ILE C . n 
B 1 64 ARG 64 62 62 ARG ARG C . n 
B 1 65 VAL 65 63 63 VAL VAL C . n 
B 1 66 TYR 66 64 64 TYR TYR C . n 
B 1 67 ALA 67 65 65 ALA ALA C . n 
B 1 68 SER 68 66 66 SER SER C . n 
B 1 69 THR 69 67 67 THR THR C . n 
B 1 70 GLY 70 68 68 GLY GLY C . n 
B 1 71 THR 71 69 69 THR THR C . n 
B 1 72 THR 72 70 70 THR THR C . n 
B 1 73 THR 73 71 71 THR THR C . n 
B 1 74 THR 74 72 72 THR THR C . n 
B 1 75 GLU 75 73 73 GLU GLU C . n 
B 1 76 TRP 76 74 74 TRP TRP C . n 
B 1 77 CYS 77 75 75 CYS CYS C . n 
B 1 78 TRP 78 76 76 TRP TRP C . n 
B 1 79 ASP 79 77 77 ASP ASP C . n 
B 1 80 GLY 80 78 78 GLY GLY C . n 
B 1 81 ASN 81 79 79 ASN ASN C . n 
B 1 82 GLY 82 80 80 GLY GLY C . n 
B 1 83 TRP 83 81 81 TRP TRP C . n 
B 1 84 THR 84 82 82 THR THR C . n 
B 1 85 LYS 85 83 83 LYS LYS C . n 
B 1 86 GLY 86 84 84 GLY GLY C . n 
B 1 87 ALA 87 85 85 ALA ALA C . n 
B 1 88 TYR 88 86 86 TYR TYR C . n 
B 1 89 THR 89 87 87 THR THR C . n 
B 1 90 ALA 90 88 88 ALA ALA C . n 
B 1 91 THR 91 89 89 THR THR C . n 
B 1 92 ASN 92 90 90 ASN ASN C . n 
C 1 1  MET 1  -1 ?  ?   ?   E . n 
C 1 2  LYS 2  0  0  LYS LYS E . n 
C 1 3  ALA 3  1  1  ALA ALA E . n 
C 1 4  SER 4  2  2  SER SER E . n 
C 1 5  VAL 5  3  3  VAL VAL E . n 
C 1 6  GLN 6  4  4  GLN GLN E . n 
C 1 7  THR 7  5  5  THR THR E . n 
C 1 8  ALA 8  6  6  ALA ALA E . n 
C 1 9  ALA 9  7  7  ALA ALA E . n 
C 1 10 THR 10 8  8  THR THR E . n 
C 1 11 SER 11 9  9  SER SER E . n 
C 1 12 TRP 12 10 10 TRP TRP E . n 
C 1 13 GLY 13 11 11 GLY GLY E . n 
C 1 14 THR 14 12 12 THR THR E . n 
C 1 15 VAL 15 13 13 VAL VAL E . n 
C 1 16 PRO 16 14 14 PRO PRO E . n 
C 1 17 SER 17 15 15 SER SER E . n 
C 1 18 ILE 18 16 16 ILE ILE E . n 
C 1 19 ARG 19 17 17 ARG ARG E . n 
C 1 20 VAL 20 18 18 VAL VAL E . n 
C 1 21 TYR 21 19 19 TYR TYR E . n 
C 1 22 THR 22 20 20 THR THR E . n 
C 1 23 ALA 23 21 21 ALA ALA E . n 
C 1 24 ASN 24 22 22 ASN ASN E . n 
C 1 25 ASN 25 23 23 ASN ASN E . n 
C 1 26 GLY 26 24 24 GLY GLY E . n 
C 1 27 LYS 27 25 25 LYS LYS E . n 
C 1 28 ILE 28 26 26 ILE ILE E . n 
C 1 29 THR 29 27 27 THR THR E . n 
C 1 30 GLU 30 28 28 GLU GLU E . n 
C 1 31 ARG 31 29 29 ARG ARG E . n 
C 1 32 CYS 32 30 30 CYS CYS E . n 
C 1 33 TRP 33 31 31 TRP TRP E . n 
C 1 34 ASP 34 32 32 ASP ASP E . n 
C 1 35 GLY 35 33 33 GLY GLY E . n 
C 1 36 LYS 36 34 34 LYS LYS E . n 
C 1 37 GLY 37 35 35 GLY GLY E . n 
C 1 38 TRP 38 36 36 TRP TRP E . n 
C 1 39 TYR 39 37 37 TYR TYR E . n 
C 1 40 THR 40 38 38 THR THR E . n 
C 1 41 GLY 41 39 39 GLY GLY E . n 
C 1 42 ALA 42 40 40 ALA ALA E . n 
C 1 43 PHE 43 41 41 PHE PHE E . n 
C 1 44 ASN 44 42 42 ASN ASN E . n 
C 1 45 GLU 45 43 43 GLU GLU E . n 
C 1 46 PRO 46 44 44 PRO PRO E . n 
C 1 47 GLY 47 45 45 GLY GLY E . n 
C 1 48 ASP 48 46 46 ASP ASP E . n 
C 1 49 ASN 49 47 47 ASN ASN E . n 
C 1 50 VAL 50 48 48 VAL VAL E . n 
C 1 51 SER 51 49 49 SER SER E . n 
C 1 52 VAL 52 50 50 VAL VAL E . n 
C 1 53 THR 53 51 51 THR THR E . n 
C 1 54 SER 54 52 52 SER SER E . n 
C 1 55 TRP 55 53 53 TRP TRP E . n 
C 1 56 LEU 56 54 54 LEU LEU E . n 
C 1 57 VAL 57 55 55 VAL VAL E . n 
C 1 58 GLY 58 56 56 GLY GLY E . n 
C 1 59 SER 59 57 57 SER SER E . n 
C 1 60 ALA 60 58 58 ALA ALA E . n 
C 1 61 ILE 61 59 59 ILE ILE E . n 
C 1 62 HIS 62 60 60 HIS HIS E . n 
C 1 63 ILE 63 61 61 ILE ILE E . n 
C 1 64 ARG 64 62 62 ARG ARG E . n 
C 1 65 VAL 65 63 63 VAL VAL E . n 
C 1 66 TYR 66 64 64 TYR TYR E . n 
C 1 67 ALA 67 65 65 ALA ALA E . n 
C 1 68 SER 68 66 66 SER SER E . n 
C 1 69 THR 69 67 67 THR THR E . n 
C 1 70 GLY 70 68 68 GLY GLY E . n 
C 1 71 THR 71 69 69 THR THR E . n 
C 1 72 THR 72 70 70 THR THR E . n 
C 1 73 THR 73 71 71 THR THR E . n 
C 1 74 THR 74 72 72 THR THR E . n 
C 1 75 GLU 75 73 73 GLU GLU E . n 
C 1 76 TRP 76 74 74 TRP TRP E . n 
C 1 77 CYS 77 75 75 CYS CYS E . n 
C 1 78 TRP 78 76 76 TRP TRP E . n 
C 1 79 ASP 79 77 77 ASP ASP E . n 
C 1 80 GLY 80 78 78 GLY GLY E . n 
C 1 81 ASN 81 79 79 ASN ASN E . n 
C 1 82 GLY 82 80 80 GLY GLY E . n 
C 1 83 TRP 83 81 81 TRP TRP E . n 
C 1 84 THR 84 82 82 THR THR E . n 
C 1 85 LYS 85 83 83 LYS LYS E . n 
C 1 86 GLY 86 84 84 GLY GLY E . n 
C 1 87 ALA 87 85 85 ALA ALA E . n 
C 1 88 TYR 88 86 86 TYR TYR E . n 
C 1 89 THR 89 87 87 THR THR E . n 
C 1 90 ALA 90 88 88 ALA ALA E . n 
C 1 91 THR 91 89 89 THR THR E . n 
C 1 92 ASN 92 90 90 ASN ASN E . n 
D 1 1  MET 1  -1 ?  ?   ?   F . n 
D 1 2  LYS 2  0  ?  ?   ?   F . n 
D 1 3  ALA 3  1  1  ALA ALA F . n 
D 1 4  SER 4  2  2  SER SER F . n 
D 1 5  VAL 5  3  3  VAL VAL F . n 
D 1 6  GLN 6  4  4  GLN GLN F . n 
D 1 7  THR 7  5  5  THR THR F . n 
D 1 8  ALA 8  6  6  ALA ALA F . n 
D 1 9  ALA 9  7  7  ALA ALA F . n 
D 1 10 THR 10 8  8  THR THR F . n 
D 1 11 SER 11 9  9  SER SER F . n 
D 1 12 TRP 12 10 10 TRP TRP F . n 
D 1 13 GLY 13 11 11 GLY GLY F . n 
D 1 14 THR 14 12 12 THR THR F . n 
D 1 15 VAL 15 13 13 VAL VAL F . n 
D 1 16 PRO 16 14 14 PRO PRO F . n 
D 1 17 SER 17 15 15 SER SER F . n 
D 1 18 ILE 18 16 16 ILE ILE F . n 
D 1 19 ARG 19 17 17 ARG ARG F . n 
D 1 20 VAL 20 18 18 VAL VAL F . n 
D 1 21 TYR 21 19 19 TYR TYR F . n 
D 1 22 THR 22 20 20 THR THR F . n 
D 1 23 ALA 23 21 21 ALA ALA F . n 
D 1 24 ASN 24 22 22 ASN ASN F . n 
D 1 25 ASN 25 23 23 ASN ASN F . n 
D 1 26 GLY 26 24 24 GLY GLY F . n 
D 1 27 LYS 27 25 25 LYS LYS F . n 
D 1 28 ILE 28 26 26 ILE ILE F . n 
D 1 29 THR 29 27 27 THR THR F . n 
D 1 30 GLU 30 28 28 GLU GLU F . n 
D 1 31 ARG 31 29 29 ARG ARG F . n 
D 1 32 CYS 32 30 30 CYS CYS F . n 
D 1 33 TRP 33 31 31 TRP TRP F . n 
D 1 34 ASP 34 32 32 ASP ASP F . n 
D 1 35 GLY 35 33 33 GLY GLY F . n 
D 1 36 LYS 36 34 34 LYS LYS F . n 
D 1 37 GLY 37 35 35 GLY GLY F . n 
D 1 38 TRP 38 36 36 TRP TRP F . n 
D 1 39 TYR 39 37 37 TYR TYR F . n 
D 1 40 THR 40 38 38 THR THR F . n 
D 1 41 GLY 41 39 39 GLY GLY F . n 
D 1 42 ALA 42 40 40 ALA ALA F . n 
D 1 43 PHE 43 41 41 PHE PHE F . n 
D 1 44 ASN 44 42 42 ASN ASN F . n 
D 1 45 GLU 45 43 43 GLU GLU F . n 
D 1 46 PRO 46 44 44 PRO PRO F . n 
D 1 47 GLY 47 45 45 GLY GLY F . n 
D 1 48 ASP 48 46 46 ASP ASP F . n 
D 1 49 ASN 49 47 47 ASN ASN F . n 
D 1 50 VAL 50 48 48 VAL VAL F . n 
D 1 51 SER 51 49 49 SER SER F . n 
D 1 52 VAL 52 50 50 VAL VAL F . n 
D 1 53 THR 53 51 51 THR THR F . n 
D 1 54 SER 54 52 52 SER SER F . n 
D 1 55 TRP 55 53 53 TRP TRP F . n 
D 1 56 LEU 56 54 54 LEU LEU F . n 
D 1 57 VAL 57 55 55 VAL VAL F . n 
D 1 58 GLY 58 56 56 GLY GLY F . n 
D 1 59 SER 59 57 57 SER SER F . n 
D 1 60 ALA 60 58 58 ALA ALA F . n 
D 1 61 ILE 61 59 59 ILE ILE F . n 
D 1 62 HIS 62 60 60 HIS HIS F . n 
D 1 63 ILE 63 61 61 ILE ILE F . n 
D 1 64 ARG 64 62 62 ARG ARG F . n 
D 1 65 VAL 65 63 63 VAL VAL F . n 
D 1 66 TYR 66 64 64 TYR TYR F . n 
D 1 67 ALA 67 65 65 ALA ALA F . n 
D 1 68 SER 68 66 66 SER SER F . n 
D 1 69 THR 69 67 67 THR THR F . n 
D 1 70 GLY 70 68 68 GLY GLY F . n 
D 1 71 THR 71 69 69 THR THR F . n 
D 1 72 THR 72 70 70 THR THR F . n 
D 1 73 THR 73 71 71 THR THR F . n 
D 1 74 THR 74 72 72 THR THR F . n 
D 1 75 GLU 75 73 73 GLU GLU F . n 
D 1 76 TRP 76 74 74 TRP TRP F . n 
D 1 77 CYS 77 75 75 CYS CYS F . n 
D 1 78 TRP 78 76 76 TRP TRP F . n 
D 1 79 ASP 79 77 77 ASP ASP F . n 
D 1 80 GLY 80 78 78 GLY GLY F . n 
D 1 81 ASN 81 79 79 ASN ASN F . n 
D 1 82 GLY 82 80 80 GLY GLY F . n 
D 1 83 TRP 83 81 81 TRP TRP F . n 
D 1 84 THR 84 82 82 THR THR F . n 
D 1 85 LYS 85 83 83 LYS LYS F . n 
D 1 86 GLY 86 84 84 GLY GLY F . n 
D 1 87 ALA 87 85 85 ALA ALA F . n 
D 1 88 TYR 88 86 86 TYR TYR F . n 
D 1 89 THR 89 87 87 THR THR F . n 
D 1 90 ALA 90 88 88 ALA ALA F . n 
D 1 91 THR 91 89 89 THR THR F . n 
D 1 92 ASN 92 90 90 ASN ASN F . n 
E 1 1  MET 1  -1 ?  ?   ?   D . n 
E 1 2  LYS 2  0  ?  ?   ?   D . n 
E 1 3  ALA 3  1  1  ALA ALA D . n 
E 1 4  SER 4  2  2  SER SER D . n 
E 1 5  VAL 5  3  3  VAL VAL D . n 
E 1 6  GLN 6  4  4  GLN GLN D . n 
E 1 7  THR 7  5  5  THR THR D . n 
E 1 8  ALA 8  6  6  ALA ALA D . n 
E 1 9  ALA 9  7  7  ALA ALA D . n 
E 1 10 THR 10 8  8  THR THR D . n 
E 1 11 SER 11 9  9  SER SER D . n 
E 1 12 TRP 12 10 10 TRP TRP D . n 
E 1 13 GLY 13 11 11 GLY GLY D . n 
E 1 14 THR 14 12 12 THR THR D . n 
E 1 15 VAL 15 13 13 VAL VAL D . n 
E 1 16 PRO 16 14 14 PRO PRO D . n 
E 1 17 SER 17 15 15 SER SER D . n 
E 1 18 ILE 18 16 16 ILE ILE D . n 
E 1 19 ARG 19 17 17 ARG ARG D . n 
E 1 20 VAL 20 18 18 VAL VAL D . n 
E 1 21 TYR 21 19 19 TYR TYR D . n 
E 1 22 THR 22 20 20 THR THR D . n 
E 1 23 ALA 23 21 21 ALA ALA D . n 
E 1 24 ASN 24 22 22 ASN ASN D . n 
E 1 25 ASN 25 23 23 ASN ASN D . n 
E 1 26 GLY 26 24 24 GLY GLY D . n 
E 1 27 LYS 27 25 25 LYS LYS D . n 
E 1 28 ILE 28 26 26 ILE ILE D . n 
E 1 29 THR 29 27 27 THR THR D . n 
E 1 30 GLU 30 28 28 GLU GLU D . n 
E 1 31 ARG 31 29 29 ARG ARG D . n 
E 1 32 CYS 32 30 30 CYS CYS D . n 
E 1 33 TRP 33 31 31 TRP TRP D . n 
E 1 34 ASP 34 32 32 ASP ASP D . n 
E 1 35 GLY 35 33 33 GLY GLY D . n 
E 1 36 LYS 36 34 34 LYS LYS D . n 
E 1 37 GLY 37 35 35 GLY GLY D . n 
E 1 38 TRP 38 36 36 TRP TRP D . n 
E 1 39 TYR 39 37 37 TYR TYR D . n 
E 1 40 THR 40 38 38 THR THR D . n 
E 1 41 GLY 41 39 39 GLY GLY D . n 
E 1 42 ALA 42 40 40 ALA ALA D . n 
E 1 43 PHE 43 41 41 PHE PHE D . n 
E 1 44 ASN 44 42 42 ASN ASN D . n 
E 1 45 GLU 45 43 43 GLU GLU D . n 
E 1 46 PRO 46 44 44 PRO PRO D . n 
E 1 47 GLY 47 45 45 GLY GLY D . n 
E 1 48 ASP 48 46 46 ASP ASP D . n 
E 1 49 ASN 49 47 47 ASN ASN D . n 
E 1 50 VAL 50 48 48 VAL VAL D . n 
E 1 51 SER 51 49 49 SER SER D . n 
E 1 52 VAL 52 50 50 VAL VAL D . n 
E 1 53 THR 53 51 51 THR THR D . n 
E 1 54 SER 54 52 52 SER SER D . n 
E 1 55 TRP 55 53 53 TRP TRP D . n 
E 1 56 LEU 56 54 54 LEU LEU D . n 
E 1 57 VAL 57 55 55 VAL VAL D . n 
E 1 58 GLY 58 56 56 GLY GLY D . n 
E 1 59 SER 59 57 57 SER SER D . n 
E 1 60 ALA 60 58 58 ALA ALA D . n 
E 1 61 ILE 61 59 59 ILE ILE D . n 
E 1 62 HIS 62 60 60 HIS HIS D . n 
E 1 63 ILE 63 61 61 ILE ILE D . n 
E 1 64 ARG 64 62 62 ARG ARG D . n 
E 1 65 VAL 65 63 63 VAL VAL D . n 
E 1 66 TYR 66 64 64 TYR TYR D . n 
E 1 67 ALA 67 65 65 ALA ALA D . n 
E 1 68 SER 68 66 66 SER SER D . n 
E 1 69 THR 69 67 67 THR THR D . n 
E 1 70 GLY 70 68 68 GLY GLY D . n 
E 1 71 THR 71 69 69 THR THR D . n 
E 1 72 THR 72 70 70 THR THR D . n 
E 1 73 THR 73 71 71 THR THR D . n 
E 1 74 THR 74 72 72 THR THR D . n 
E 1 75 GLU 75 73 73 GLU GLU D . n 
E 1 76 TRP 76 74 74 TRP TRP D . n 
E 1 77 CYS 77 75 75 CYS CYS D . n 
E 1 78 TRP 78 76 76 TRP TRP D . n 
E 1 79 ASP 79 77 77 ASP ASP D . n 
E 1 80 GLY 80 78 78 GLY GLY D . n 
E 1 81 ASN 81 79 79 ASN ASN D . n 
E 1 82 GLY 82 80 80 GLY GLY D . n 
E 1 83 TRP 83 81 81 TRP TRP D . n 
E 1 84 THR 84 82 82 THR THR D . n 
E 1 85 LYS 85 83 83 LYS LYS D . n 
E 1 86 GLY 86 84 84 GLY GLY D . n 
E 1 87 ALA 87 85 85 ALA ALA D . n 
E 1 88 TYR 88 86 86 TYR TYR D . n 
E 1 89 THR 89 87 87 THR THR D . n 
E 1 90 ALA 90 88 88 ALA ALA D . n 
E 1 91 THR 91 89 89 THR THR D . n 
E 1 92 ASN 92 90 90 ASN ASN D . n 
F 1 1  MET 1  -1 -1 MET MET A . n 
F 1 2  LYS 2  0  0  LYS LYS A . n 
F 1 3  ALA 3  1  1  ALA ALA A . n 
F 1 4  SER 4  2  2  SER SER A . n 
F 1 5  VAL 5  3  3  VAL VAL A . n 
F 1 6  GLN 6  4  4  GLN GLN A . n 
F 1 7  THR 7  5  5  THR THR A . n 
F 1 8  ALA 8  6  6  ALA ALA A . n 
F 1 9  ALA 9  7  7  ALA ALA A . n 
F 1 10 THR 10 8  8  THR THR A . n 
F 1 11 SER 11 9  9  SER SER A . n 
F 1 12 TRP 12 10 10 TRP TRP A . n 
F 1 13 GLY 13 11 11 GLY GLY A . n 
F 1 14 THR 14 12 12 THR THR A . n 
F 1 15 VAL 15 13 13 VAL VAL A . n 
F 1 16 PRO 16 14 14 PRO PRO A . n 
F 1 17 SER 17 15 15 SER SER A . n 
F 1 18 ILE 18 16 16 ILE ILE A . n 
F 1 19 ARG 19 17 17 ARG ARG A . n 
F 1 20 VAL 20 18 18 VAL VAL A . n 
F 1 21 TYR 21 19 19 TYR TYR A . n 
F 1 22 THR 22 20 20 THR THR A . n 
F 1 23 ALA 23 21 21 ALA ALA A . n 
F 1 24 ASN 24 22 22 ASN ASN A . n 
F 1 25 ASN 25 23 23 ASN ASN A . n 
F 1 26 GLY 26 24 24 GLY GLY A . n 
F 1 27 LYS 27 25 25 LYS LYS A . n 
F 1 28 ILE 28 26 26 ILE ILE A . n 
F 1 29 THR 29 27 27 THR THR A . n 
F 1 30 GLU 30 28 28 GLU GLU A . n 
F 1 31 ARG 31 29 29 ARG ARG A . n 
F 1 32 CYS 32 30 30 CYS CYS A . n 
F 1 33 TRP 33 31 31 TRP TRP A . n 
F 1 34 ASP 34 32 32 ASP ASP A . n 
F 1 35 GLY 35 33 33 GLY GLY A . n 
F 1 36 LYS 36 34 34 LYS LYS A . n 
F 1 37 GLY 37 35 35 GLY GLY A . n 
F 1 38 TRP 38 36 36 TRP TRP A . n 
F 1 39 TYR 39 37 37 TYR TYR A . n 
F 1 40 THR 40 38 38 THR THR A . n 
F 1 41 GLY 41 39 39 GLY GLY A . n 
F 1 42 ALA 42 40 40 ALA ALA A . n 
F 1 43 PHE 43 41 41 PHE PHE A . n 
F 1 44 ASN 44 42 42 ASN ASN A . n 
F 1 45 GLU 45 43 43 GLU GLU A . n 
F 1 46 PRO 46 44 44 PRO PRO A . n 
F 1 47 GLY 47 45 45 GLY GLY A . n 
F 1 48 ASP 48 46 46 ASP ASP A . n 
F 1 49 ASN 49 47 47 ASN ASN A . n 
F 1 50 VAL 50 48 48 VAL VAL A . n 
F 1 51 SER 51 49 49 SER SER A . n 
F 1 52 VAL 52 50 50 VAL VAL A . n 
F 1 53 THR 53 51 51 THR THR A . n 
F 1 54 SER 54 52 52 SER SER A . n 
F 1 55 TRP 55 53 53 TRP TRP A . n 
F 1 56 LEU 56 54 54 LEU LEU A . n 
F 1 57 VAL 57 55 55 VAL VAL A . n 
F 1 58 GLY 58 56 56 GLY GLY A . n 
F 1 59 SER 59 57 57 SER SER A . n 
F 1 60 ALA 60 58 58 ALA ALA A . n 
F 1 61 ILE 61 59 59 ILE ILE A . n 
F 1 62 HIS 62 60 60 HIS HIS A . n 
F 1 63 ILE 63 61 61 ILE ILE A . n 
F 1 64 ARG 64 62 62 ARG ARG A . n 
F 1 65 VAL 65 63 63 VAL VAL A . n 
F 1 66 TYR 66 64 64 TYR TYR A . n 
F 1 67 ALA 67 65 65 ALA ALA A . n 
F 1 68 SER 68 66 66 SER SER A . n 
F 1 69 THR 69 67 67 THR THR A . n 
F 1 70 GLY 70 68 68 GLY GLY A . n 
F 1 71 THR 71 69 69 THR THR A . n 
F 1 72 THR 72 70 70 THR THR A . n 
F 1 73 THR 73 71 71 THR THR A . n 
F 1 74 THR 74 72 72 THR THR A . n 
F 1 75 GLU 75 73 73 GLU GLU A . n 
F 1 76 TRP 76 74 74 TRP TRP A . n 
F 1 77 CYS 77 75 75 CYS CYS A . n 
F 1 78 TRP 78 76 76 TRP TRP A . n 
F 1 79 ASP 79 77 77 ASP ASP A . n 
F 1 80 GLY 80 78 78 GLY GLY A . n 
F 1 81 ASN 81 79 79 ASN ASN A . n 
F 1 82 GLY 82 80 80 GLY GLY A . n 
F 1 83 TRP 83 81 81 TRP TRP A . n 
F 1 84 THR 84 82 82 THR THR A . n 
F 1 85 LYS 85 83 83 LYS LYS A . n 
F 1 86 GLY 86 84 84 GLY GLY A . n 
F 1 87 ALA 87 85 85 ALA ALA A . n 
F 1 88 TYR 88 86 86 TYR TYR A . n 
F 1 89 THR 89 87 87 THR THR A . n 
F 1 90 ALA 90 88 88 ALA ALA A . n 
F 1 91 THR 91 89 89 THR THR A . n 
F 1 92 ASN 92 90 90 ASN ASN A . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 BDF ? ? BDF ? ? 'SUBJECT OF INVESTIGATION' ? 
2 T3Y ? ? T3Y ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G  2 BDF 1   101 101  BDF BDF B . 
H  2 BDF 1   102 201  BDF BDF B . 
I  3 T3Y 1   101 101  T3Y T3Y C . 
J  2 BDF 1   102 201  BDF BDF C . 
K  2 BDF 1   103 301  BDF BDF C . 
L  3 T3Y 1   101 101  T3Y T3Y E . 
M  2 BDF 1   102 201  BDF BDF E . 
N  2 BDF 1   103 301  BDF BDF E . 
O  2 BDF 1   101 101  BDF BDF F . 
P  2 BDF 1   102 201  BDF BDF F . 
Q  2 BDF 1   101 101  BDF BDF D . 
R  2 BDF 1   102 201  BDF BDF D . 
S  3 T3Y 1   101 101  T3Y T3Y A . 
T  2 BDF 1   102 201  BDF BDF A . 
U  2 BDF 1   103 301  BDF BDF A . 
V  4 HOH 1   201 459  HOH HOH B . 
V  4 HOH 2   202 383  HOH HOH B . 
V  4 HOH 3   203 573  HOH HOH B . 
V  4 HOH 4   204 470  HOH HOH B . 
V  4 HOH 5   205 662  HOH HOH B . 
V  4 HOH 6   206 267  HOH HOH B . 
V  4 HOH 7   207 260  HOH HOH B . 
V  4 HOH 8   208 60   HOH HOH B . 
V  4 HOH 9   209 923  HOH HOH B . 
V  4 HOH 10  210 988  HOH HOH B . 
V  4 HOH 11  211 1019 HOH HOH B . 
V  4 HOH 12  212 300  HOH HOH B . 
V  4 HOH 13  213 68   HOH HOH B . 
V  4 HOH 14  214 504  HOH HOH B . 
V  4 HOH 15  215 882  HOH HOH B . 
V  4 HOH 16  216 197  HOH HOH B . 
V  4 HOH 17  217 447  HOH HOH B . 
V  4 HOH 18  218 115  HOH HOH B . 
V  4 HOH 19  219 418  HOH HOH B . 
V  4 HOH 20  220 13   HOH HOH B . 
V  4 HOH 21  221 203  HOH HOH B . 
V  4 HOH 22  222 959  HOH HOH B . 
V  4 HOH 23  223 167  HOH HOH B . 
V  4 HOH 24  224 456  HOH HOH B . 
V  4 HOH 25  225 77   HOH HOH B . 
V  4 HOH 26  226 39   HOH HOH B . 
V  4 HOH 27  227 34   HOH HOH B . 
V  4 HOH 28  228 639  HOH HOH B . 
V  4 HOH 29  229 991  HOH HOH B . 
V  4 HOH 30  230 407  HOH HOH B . 
V  4 HOH 31  231 139  HOH HOH B . 
V  4 HOH 32  232 411  HOH HOH B . 
V  4 HOH 33  233 258  HOH HOH B . 
V  4 HOH 34  234 252  HOH HOH B . 
V  4 HOH 35  235 934  HOH HOH B . 
V  4 HOH 36  236 8    HOH HOH B . 
V  4 HOH 37  237 843  HOH HOH B . 
V  4 HOH 38  238 510  HOH HOH B . 
V  4 HOH 39  239 1185 HOH HOH B . 
V  4 HOH 40  240 806  HOH HOH B . 
V  4 HOH 41  241 544  HOH HOH B . 
V  4 HOH 42  242 1181 HOH HOH B . 
V  4 HOH 43  243 922  HOH HOH B . 
V  4 HOH 44  244 257  HOH HOH B . 
V  4 HOH 45  245 828  HOH HOH B . 
V  4 HOH 46  246 1196 HOH HOH B . 
V  4 HOH 47  247 176  HOH HOH B . 
V  4 HOH 48  248 43   HOH HOH B . 
V  4 HOH 49  249 992  HOH HOH B . 
V  4 HOH 50  250 268  HOH HOH B . 
V  4 HOH 51  251 580  HOH HOH B . 
V  4 HOH 52  252 365  HOH HOH B . 
V  4 HOH 53  253 1172 HOH HOH B . 
V  4 HOH 54  254 140  HOH HOH B . 
V  4 HOH 55  255 38   HOH HOH B . 
V  4 HOH 56  256 579  HOH HOH B . 
V  4 HOH 57  257 1111 HOH HOH B . 
V  4 HOH 58  258 327  HOH HOH B . 
V  4 HOH 59  259 883  HOH HOH B . 
V  4 HOH 60  260 278  HOH HOH B . 
V  4 HOH 61  261 648  HOH HOH B . 
V  4 HOH 62  262 132  HOH HOH B . 
V  4 HOH 63  263 280  HOH HOH B . 
V  4 HOH 64  264 475  HOH HOH B . 
V  4 HOH 65  265 316  HOH HOH B . 
V  4 HOH 66  266 269  HOH HOH B . 
V  4 HOH 67  267 190  HOH HOH B . 
V  4 HOH 68  268 92   HOH HOH B . 
V  4 HOH 69  269 398  HOH HOH B . 
V  4 HOH 70  270 1208 HOH HOH B . 
V  4 HOH 71  271 332  HOH HOH B . 
V  4 HOH 72  272 474  HOH HOH B . 
V  4 HOH 73  273 942  HOH HOH B . 
V  4 HOH 74  274 479  HOH HOH B . 
V  4 HOH 75  275 427  HOH HOH B . 
V  4 HOH 76  276 660  HOH HOH B . 
V  4 HOH 77  277 266  HOH HOH B . 
V  4 HOH 78  278 147  HOH HOH B . 
V  4 HOH 79  279 963  HOH HOH B . 
V  4 HOH 80  280 226  HOH HOH B . 
V  4 HOH 81  281 81   HOH HOH B . 
V  4 HOH 82  282 131  HOH HOH B . 
V  4 HOH 83  283 560  HOH HOH B . 
V  4 HOH 84  284 467  HOH HOH B . 
V  4 HOH 85  285 186  HOH HOH B . 
V  4 HOH 86  286 1076 HOH HOH B . 
V  4 HOH 87  287 360  HOH HOH B . 
V  4 HOH 88  288 346  HOH HOH B . 
V  4 HOH 89  289 856  HOH HOH B . 
V  4 HOH 90  290 593  HOH HOH B . 
V  4 HOH 91  291 559  HOH HOH B . 
V  4 HOH 92  292 759  HOH HOH B . 
V  4 HOH 93  293 200  HOH HOH B . 
V  4 HOH 94  294 229  HOH HOH B . 
V  4 HOH 95  295 1109 HOH HOH B . 
V  4 HOH 96  296 389  HOH HOH B . 
V  4 HOH 97  297 491  HOH HOH B . 
V  4 HOH 98  298 912  HOH HOH B . 
V  4 HOH 99  299 885  HOH HOH B . 
V  4 HOH 100 300 369  HOH HOH B . 
V  4 HOH 101 301 594  HOH HOH B . 
V  4 HOH 102 302 476  HOH HOH B . 
V  4 HOH 103 303 337  HOH HOH B . 
V  4 HOH 104 304 340  HOH HOH B . 
V  4 HOH 105 305 784  HOH HOH B . 
V  4 HOH 106 306 231  HOH HOH B . 
V  4 HOH 107 307 1013 HOH HOH B . 
V  4 HOH 108 308 460  HOH HOH B . 
V  4 HOH 109 309 473  HOH HOH B . 
V  4 HOH 110 310 357  HOH HOH B . 
V  4 HOH 111 311 607  HOH HOH B . 
V  4 HOH 112 312 377  HOH HOH B . 
V  4 HOH 113 313 966  HOH HOH B . 
V  4 HOH 114 314 910  HOH HOH B . 
V  4 HOH 115 315 954  HOH HOH B . 
V  4 HOH 116 316 1213 HOH HOH B . 
W  4 HOH 1   201 382  HOH HOH C . 
W  4 HOH 2   202 344  HOH HOH C . 
W  4 HOH 3   203 263  HOH HOH C . 
W  4 HOH 4   204 743  HOH HOH C . 
W  4 HOH 5   205 426  HOH HOH C . 
W  4 HOH 6   206 1007 HOH HOH C . 
W  4 HOH 7   207 436  HOH HOH C . 
W  4 HOH 8   208 1180 HOH HOH C . 
W  4 HOH 9   209 762  HOH HOH C . 
W  4 HOH 10  210 17   HOH HOH C . 
W  4 HOH 11  211 251  HOH HOH C . 
W  4 HOH 12  212 114  HOH HOH C . 
W  4 HOH 13  213 361  HOH HOH C . 
W  4 HOH 14  214 27   HOH HOH C . 
W  4 HOH 15  215 688  HOH HOH C . 
W  4 HOH 16  216 215  HOH HOH C . 
W  4 HOH 17  217 170  HOH HOH C . 
W  4 HOH 18  218 461  HOH HOH C . 
W  4 HOH 19  219 123  HOH HOH C . 
W  4 HOH 20  220 126  HOH HOH C . 
W  4 HOH 21  221 242  HOH HOH C . 
W  4 HOH 22  222 571  HOH HOH C . 
W  4 HOH 23  223 672  HOH HOH C . 
W  4 HOH 24  224 248  HOH HOH C . 
W  4 HOH 25  225 465  HOH HOH C . 
W  4 HOH 26  226 338  HOH HOH C . 
W  4 HOH 27  227 99   HOH HOH C . 
W  4 HOH 28  228 836  HOH HOH C . 
W  4 HOH 29  229 35   HOH HOH C . 
W  4 HOH 30  230 270  HOH HOH C . 
W  4 HOH 31  231 649  HOH HOH C . 
W  4 HOH 32  232 829  HOH HOH C . 
W  4 HOH 33  233 221  HOH HOH C . 
W  4 HOH 34  234 446  HOH HOH C . 
W  4 HOH 35  235 40   HOH HOH C . 
W  4 HOH 36  236 125  HOH HOH C . 
W  4 HOH 37  237 656  HOH HOH C . 
W  4 HOH 38  238 11   HOH HOH C . 
W  4 HOH 39  239 1166 HOH HOH C . 
W  4 HOH 40  240 433  HOH HOH C . 
W  4 HOH 41  241 1164 HOH HOH C . 
W  4 HOH 42  242 73   HOH HOH C . 
W  4 HOH 43  243 153  HOH HOH C . 
W  4 HOH 44  244 236  HOH HOH C . 
W  4 HOH 45  245 238  HOH HOH C . 
W  4 HOH 46  246 1174 HOH HOH C . 
W  4 HOH 47  247 469  HOH HOH C . 
W  4 HOH 48  248 381  HOH HOH C . 
W  4 HOH 49  249 51   HOH HOH C . 
W  4 HOH 50  250 88   HOH HOH C . 
W  4 HOH 51  251 453  HOH HOH C . 
W  4 HOH 52  252 538  HOH HOH C . 
W  4 HOH 53  253 413  HOH HOH C . 
W  4 HOH 54  254 804  HOH HOH C . 
W  4 HOH 55  255 1229 HOH HOH C . 
W  4 HOH 56  256 949  HOH HOH C . 
W  4 HOH 57  257 1203 HOH HOH C . 
W  4 HOH 58  258 285  HOH HOH C . 
W  4 HOH 59  259 1168 HOH HOH C . 
W  4 HOH 60  260 264  HOH HOH C . 
W  4 HOH 61  261 108  HOH HOH C . 
W  4 HOH 62  262 110  HOH HOH C . 
W  4 HOH 63  263 311  HOH HOH C . 
W  4 HOH 64  264 837  HOH HOH C . 
W  4 HOH 65  265 626  HOH HOH C . 
W  4 HOH 66  266 47   HOH HOH C . 
W  4 HOH 67  267 1178 HOH HOH C . 
W  4 HOH 68  268 1017 HOH HOH C . 
W  4 HOH 69  269 567  HOH HOH C . 
W  4 HOH 70  270 91   HOH HOH C . 
W  4 HOH 71  271 9    HOH HOH C . 
W  4 HOH 72  272 869  HOH HOH C . 
W  4 HOH 73  273 944  HOH HOH C . 
W  4 HOH 74  274 484  HOH HOH C . 
W  4 HOH 75  275 1118 HOH HOH C . 
W  4 HOH 76  276 1198 HOH HOH C . 
W  4 HOH 77  277 597  HOH HOH C . 
W  4 HOH 78  278 811  HOH HOH C . 
W  4 HOH 79  279 52   HOH HOH C . 
W  4 HOH 80  280 330  HOH HOH C . 
W  4 HOH 81  281 121  HOH HOH C . 
W  4 HOH 82  282 994  HOH HOH C . 
W  4 HOH 83  283 400  HOH HOH C . 
W  4 HOH 84  284 149  HOH HOH C . 
W  4 HOH 85  285 370  HOH HOH C . 
W  4 HOH 86  286 129  HOH HOH C . 
W  4 HOH 87  287 1237 HOH HOH C . 
W  4 HOH 88  288 351  HOH HOH C . 
W  4 HOH 89  289 207  HOH HOH C . 
W  4 HOH 90  290 173  HOH HOH C . 
W  4 HOH 91  291 846  HOH HOH C . 
W  4 HOH 92  292 964  HOH HOH C . 
W  4 HOH 93  293 233  HOH HOH C . 
W  4 HOH 94  294 237  HOH HOH C . 
W  4 HOH 95  295 1217 HOH HOH C . 
W  4 HOH 96  296 866  HOH HOH C . 
W  4 HOH 97  297 201  HOH HOH C . 
W  4 HOH 98  298 180  HOH HOH C . 
W  4 HOH 99  299 1207 HOH HOH C . 
W  4 HOH 100 300 388  HOH HOH C . 
W  4 HOH 101 301 507  HOH HOH C . 
W  4 HOH 102 302 938  HOH HOH C . 
W  4 HOH 103 303 79   HOH HOH C . 
W  4 HOH 104 304 781  HOH HOH C . 
W  4 HOH 105 305 309  HOH HOH C . 
W  4 HOH 106 306 895  HOH HOH C . 
W  4 HOH 107 307 72   HOH HOH C . 
W  4 HOH 108 308 134  HOH HOH C . 
W  4 HOH 109 309 240  HOH HOH C . 
W  4 HOH 110 310 1173 HOH HOH C . 
W  4 HOH 111 311 689  HOH HOH C . 
W  4 HOH 112 312 805  HOH HOH C . 
W  4 HOH 113 313 870  HOH HOH C . 
W  4 HOH 114 314 1224 HOH HOH C . 
W  4 HOH 115 315 500  HOH HOH C . 
W  4 HOH 116 316 271  HOH HOH C . 
W  4 HOH 117 317 861  HOH HOH C . 
W  4 HOH 118 318 1179 HOH HOH C . 
W  4 HOH 119 319 871  HOH HOH C . 
W  4 HOH 120 320 721  HOH HOH C . 
W  4 HOH 121 321 999  HOH HOH C . 
W  4 HOH 122 322 822  HOH HOH C . 
W  4 HOH 123 323 712  HOH HOH C . 
W  4 HOH 124 324 1002 HOH HOH C . 
W  4 HOH 125 325 598  HOH HOH C . 
W  4 HOH 126 326 289  HOH HOH C . 
W  4 HOH 127 327 1214 HOH HOH C . 
W  4 HOH 128 328 499  HOH HOH C . 
W  4 HOH 129 329 202  HOH HOH C . 
W  4 HOH 130 330 517  HOH HOH C . 
W  4 HOH 131 331 135  HOH HOH C . 
W  4 HOH 132 332 530  HOH HOH C . 
W  4 HOH 133 333 294  HOH HOH C . 
W  4 HOH 134 334 319  HOH HOH C . 
W  4 HOH 135 335 350  HOH HOH C . 
W  4 HOH 136 336 834  HOH HOH C . 
W  4 HOH 137 337 1098 HOH HOH C . 
W  4 HOH 138 338 956  HOH HOH C . 
W  4 HOH 139 339 1069 HOH HOH C . 
X  4 HOH 1   201 458  HOH HOH E . 
X  4 HOH 2   202 616  HOH HOH E . 
X  4 HOH 3   203 872  HOH HOH E . 
X  4 HOH 4   204 390  HOH HOH E . 
X  4 HOH 5   205 120  HOH HOH E . 
X  4 HOH 6   206 1048 HOH HOH E . 
X  4 HOH 7   207 584  HOH HOH E . 
X  4 HOH 8   208 519  HOH HOH E . 
X  4 HOH 9   209 853  HOH HOH E . 
X  4 HOH 10  210 568  HOH HOH E . 
X  4 HOH 11  211 435  HOH HOH E . 
X  4 HOH 12  212 490  HOH HOH E . 
X  4 HOH 13  213 445  HOH HOH E . 
X  4 HOH 14  214 160  HOH HOH E . 
X  4 HOH 15  215 478  HOH HOH E . 
X  4 HOH 16  216 25   HOH HOH E . 
X  4 HOH 17  217 310  HOH HOH E . 
X  4 HOH 18  218 1121 HOH HOH E . 
X  4 HOH 19  219 451  HOH HOH E . 
X  4 HOH 20  220 148  HOH HOH E . 
X  4 HOH 21  221 175  HOH HOH E . 
X  4 HOH 22  222 78   HOH HOH E . 
X  4 HOH 23  223 5    HOH HOH E . 
X  4 HOH 24  224 222  HOH HOH E . 
X  4 HOH 25  225 177  HOH HOH E . 
X  4 HOH 26  226 241  HOH HOH E . 
X  4 HOH 27  227 64   HOH HOH E . 
X  4 HOH 28  228 305  HOH HOH E . 
X  4 HOH 29  229 277  HOH HOH E . 
X  4 HOH 30  230 1058 HOH HOH E . 
X  4 HOH 31  231 729  HOH HOH E . 
X  4 HOH 32  232 71   HOH HOH E . 
X  4 HOH 33  233 168  HOH HOH E . 
X  4 HOH 34  234 41   HOH HOH E . 
X  4 HOH 35  235 154  HOH HOH E . 
X  4 HOH 36  236 74   HOH HOH E . 
X  4 HOH 37  237 283  HOH HOH E . 
X  4 HOH 38  238 387  HOH HOH E . 
X  4 HOH 39  239 155  HOH HOH E . 
X  4 HOH 40  240 32   HOH HOH E . 
X  4 HOH 41  241 28   HOH HOH E . 
X  4 HOH 42  242 196  HOH HOH E . 
X  4 HOH 43  243 380  HOH HOH E . 
X  4 HOH 44  244 326  HOH HOH E . 
X  4 HOH 45  245 482  HOH HOH E . 
X  4 HOH 46  246 521  HOH HOH E . 
X  4 HOH 47  247 826  HOH HOH E . 
X  4 HOH 48  248 161  HOH HOH E . 
X  4 HOH 49  249 184  HOH HOH E . 
X  4 HOH 50  250 352  HOH HOH E . 
X  4 HOH 51  251 306  HOH HOH E . 
X  4 HOH 52  252 212  HOH HOH E . 
X  4 HOH 53  253 1234 HOH HOH E . 
X  4 HOH 54  254 950  HOH HOH E . 
X  4 HOH 55  255 189  HOH HOH E . 
X  4 HOH 56  256 301  HOH HOH E . 
X  4 HOH 57  257 918  HOH HOH E . 
X  4 HOH 58  258 315  HOH HOH E . 
X  4 HOH 59  259 249  HOH HOH E . 
X  4 HOH 60  260 1071 HOH HOH E . 
X  4 HOH 61  261 860  HOH HOH E . 
X  4 HOH 62  262 3    HOH HOH E . 
X  4 HOH 63  263 83   HOH HOH E . 
X  4 HOH 64  264 437  HOH HOH E . 
X  4 HOH 65  265 235  HOH HOH E . 
X  4 HOH 66  266 58   HOH HOH E . 
X  4 HOH 67  267 204  HOH HOH E . 
X  4 HOH 68  268 506  HOH HOH E . 
X  4 HOH 69  269 65   HOH HOH E . 
X  4 HOH 70  270 324  HOH HOH E . 
X  4 HOH 71  271 93   HOH HOH E . 
X  4 HOH 72  272 216  HOH HOH E . 
X  4 HOH 73  273 162  HOH HOH E . 
X  4 HOH 74  274 317  HOH HOH E . 
X  4 HOH 75  275 234  HOH HOH E . 
X  4 HOH 76  276 259  HOH HOH E . 
X  4 HOH 77  277 223  HOH HOH E . 
X  4 HOH 78  278 130  HOH HOH E . 
X  4 HOH 79  279 1061 HOH HOH E . 
X  4 HOH 80  280 194  HOH HOH E . 
X  4 HOH 81  281 80   HOH HOH E . 
X  4 HOH 82  282 87   HOH HOH E . 
X  4 HOH 83  283 66   HOH HOH E . 
X  4 HOH 84  284 1182 HOH HOH E . 
X  4 HOH 85  285 230  HOH HOH E . 
X  4 HOH 86  286 612  HOH HOH E . 
X  4 HOH 87  287 440  HOH HOH E . 
X  4 HOH 88  288 1031 HOH HOH E . 
X  4 HOH 89  289 911  HOH HOH E . 
X  4 HOH 90  290 403  HOH HOH E . 
X  4 HOH 91  291 295  HOH HOH E . 
X  4 HOH 92  292 1175 HOH HOH E . 
X  4 HOH 93  293 244  HOH HOH E . 
X  4 HOH 94  294 307  HOH HOH E . 
X  4 HOH 95  295 7    HOH HOH E . 
X  4 HOH 96  296 1215 HOH HOH E . 
X  4 HOH 97  297 1205 HOH HOH E . 
X  4 HOH 98  298 1211 HOH HOH E . 
X  4 HOH 99  299 392  HOH HOH E . 
X  4 HOH 100 300 171  HOH HOH E . 
X  4 HOH 101 301 408  HOH HOH E . 
X  4 HOH 102 302 1056 HOH HOH E . 
X  4 HOH 103 303 849  HOH HOH E . 
X  4 HOH 104 304 409  HOH HOH E . 
X  4 HOH 105 305 1037 HOH HOH E . 
X  4 HOH 106 306 535  HOH HOH E . 
X  4 HOH 107 307 341  HOH HOH E . 
X  4 HOH 108 308 1001 HOH HOH E . 
X  4 HOH 109 309 768  HOH HOH E . 
X  4 HOH 110 310 858  HOH HOH E . 
X  4 HOH 111 311 441  HOH HOH E . 
X  4 HOH 112 312 610  HOH HOH E . 
X  4 HOH 113 313 1201 HOH HOH E . 
X  4 HOH 114 314 638  HOH HOH E . 
X  4 HOH 115 315 583  HOH HOH E . 
X  4 HOH 116 316 372  HOH HOH E . 
X  4 HOH 117 317 144  HOH HOH E . 
X  4 HOH 118 318 766  HOH HOH E . 
X  4 HOH 119 319 686  HOH HOH E . 
X  4 HOH 120 320 1067 HOH HOH E . 
X  4 HOH 121 321 543  HOH HOH E . 
X  4 HOH 122 322 847  HOH HOH E . 
X  4 HOH 123 323 163  HOH HOH E . 
X  4 HOH 124 324 220  HOH HOH E . 
X  4 HOH 125 325 452  HOH HOH E . 
X  4 HOH 126 326 314  HOH HOH E . 
X  4 HOH 127 327 245  HOH HOH E . 
X  4 HOH 128 328 183  HOH HOH E . 
X  4 HOH 129 329 815  HOH HOH E . 
X  4 HOH 130 330 472  HOH HOH E . 
X  4 HOH 131 331 1035 HOH HOH E . 
X  4 HOH 132 332 434  HOH HOH E . 
X  4 HOH 133 333 907  HOH HOH E . 
X  4 HOH 134 334 541  HOH HOH E . 
X  4 HOH 135 335 224  HOH HOH E . 
X  4 HOH 136 336 508  HOH HOH E . 
X  4 HOH 137 337 334  HOH HOH E . 
X  4 HOH 138 338 1236 HOH HOH E . 
X  4 HOH 139 339 1027 HOH HOH E . 
X  4 HOH 140 340 1034 HOH HOH E . 
X  4 HOH 141 341 1063 HOH HOH E . 
X  4 HOH 142 342 757  HOH HOH E . 
X  4 HOH 143 343 737  HOH HOH E . 
Y  4 HOH 1   201 253  HOH HOH F . 
Y  4 HOH 2   202 696  HOH HOH F . 
Y  4 HOH 3   203 810  HOH HOH F . 
Y  4 HOH 4   204 525  HOH HOH F . 
Y  4 HOH 5   205 533  HOH HOH F . 
Y  4 HOH 6   206 540  HOH HOH F . 
Y  4 HOH 7   207 513  HOH HOH F . 
Y  4 HOH 8   208 356  HOH HOH F . 
Y  4 HOH 9   209 90   HOH HOH F . 
Y  4 HOH 10  210 569  HOH HOH F . 
Y  4 HOH 11  211 6    HOH HOH F . 
Y  4 HOH 12  212 243  HOH HOH F . 
Y  4 HOH 13  213 10   HOH HOH F . 
Y  4 HOH 14  214 227  HOH HOH F . 
Y  4 HOH 15  215 46   HOH HOH F . 
Y  4 HOH 16  216 322  HOH HOH F . 
Y  4 HOH 17  217 587  HOH HOH F . 
Y  4 HOH 18  218 112  HOH HOH F . 
Y  4 HOH 19  219 293  HOH HOH F . 
Y  4 HOH 20  220 816  HOH HOH F . 
Y  4 HOH 21  221 303  HOH HOH F . 
Y  4 HOH 22  222 1235 HOH HOH F . 
Y  4 HOH 23  223 685  HOH HOH F . 
Y  4 HOH 24  224 14   HOH HOH F . 
Y  4 HOH 25  225 67   HOH HOH F . 
Y  4 HOH 26  226 214  HOH HOH F . 
Y  4 HOH 27  227 109  HOH HOH F . 
Y  4 HOH 28  228 797  HOH HOH F . 
Y  4 HOH 29  229 416  HOH HOH F . 
Y  4 HOH 30  230 262  HOH HOH F . 
Y  4 HOH 31  231 45   HOH HOH F . 
Y  4 HOH 32  232 69   HOH HOH F . 
Y  4 HOH 33  233 744  HOH HOH F . 
Y  4 HOH 34  234 250  HOH HOH F . 
Y  4 HOH 35  235 195  HOH HOH F . 
Y  4 HOH 36  236 225  HOH HOH F . 
Y  4 HOH 37  237 185  HOH HOH F . 
Y  4 HOH 38  238 546  HOH HOH F . 
Y  4 HOH 39  239 127  HOH HOH F . 
Y  4 HOH 40  240 1000 HOH HOH F . 
Y  4 HOH 41  241 671  HOH HOH F . 
Y  4 HOH 42  242 96   HOH HOH F . 
Y  4 HOH 43  243 75   HOH HOH F . 
Y  4 HOH 44  244 680  HOH HOH F . 
Y  4 HOH 45  245 116  HOH HOH F . 
Y  4 HOH 46  246 609  HOH HOH F . 
Y  4 HOH 47  247 347  HOH HOH F . 
Y  4 HOH 48  248 142  HOH HOH F . 
Y  4 HOH 49  249 1171 HOH HOH F . 
Y  4 HOH 50  250 600  HOH HOH F . 
Y  4 HOH 51  251 780  HOH HOH F . 
Y  4 HOH 52  252 37   HOH HOH F . 
Y  4 HOH 53  253 399  HOH HOH F . 
Y  4 HOH 54  254 256  HOH HOH F . 
Y  4 HOH 55  255 1165 HOH HOH F . 
Y  4 HOH 56  256 122  HOH HOH F . 
Y  4 HOH 57  257 368  HOH HOH F . 
Y  4 HOH 58  258 152  HOH HOH F . 
Y  4 HOH 59  259 835  HOH HOH F . 
Y  4 HOH 60  260 397  HOH HOH F . 
Y  4 HOH 61  261 1194 HOH HOH F . 
Y  4 HOH 62  262 402  HOH HOH F . 
Y  4 HOH 63  263 625  HOH HOH F . 
Y  4 HOH 64  264 49   HOH HOH F . 
Y  4 HOH 65  265 205  HOH HOH F . 
Y  4 HOH 66  266 590  HOH HOH F . 
Y  4 HOH 67  267 48   HOH HOH F . 
Y  4 HOH 68  268 36   HOH HOH F . 
Y  4 HOH 69  269 665  HOH HOH F . 
Y  4 HOH 70  270 684  HOH HOH F . 
Y  4 HOH 71  271 21   HOH HOH F . 
Y  4 HOH 72  272 179  HOH HOH F . 
Y  4 HOH 73  273 444  HOH HOH F . 
Y  4 HOH 74  274 198  HOH HOH F . 
Y  4 HOH 75  275 501  HOH HOH F . 
Y  4 HOH 76  276 157  HOH HOH F . 
Y  4 HOH 77  277 393  HOH HOH F . 
Y  4 HOH 78  278 288  HOH HOH F . 
Y  4 HOH 79  279 410  HOH HOH F . 
Y  4 HOH 80  280 321  HOH HOH F . 
Y  4 HOH 81  281 605  HOH HOH F . 
Y  4 HOH 82  282 948  HOH HOH F . 
Y  4 HOH 83  283 359  HOH HOH F . 
Y  4 HOH 84  284 581  HOH HOH F . 
Y  4 HOH 85  285 585  HOH HOH F . 
Y  4 HOH 86  286 104  HOH HOH F . 
Y  4 HOH 87  287 246  HOH HOH F . 
Y  4 HOH 88  288 449  HOH HOH F . 
Y  4 HOH 89  289 118  HOH HOH F . 
Y  4 HOH 90  290 995  HOH HOH F . 
Y  4 HOH 91  291 468  HOH HOH F . 
Y  4 HOH 92  292 589  HOH HOH F . 
Y  4 HOH 93  293 632  HOH HOH F . 
Y  4 HOH 94  294 339  HOH HOH F . 
Y  4 HOH 95  295 146  HOH HOH F . 
Y  4 HOH 96  296 15   HOH HOH F . 
Y  4 HOH 97  297 812  HOH HOH F . 
Y  4 HOH 98  298 876  HOH HOH F . 
Y  4 HOH 99  299 1190 HOH HOH F . 
Y  4 HOH 100 300 1204 HOH HOH F . 
Y  4 HOH 101 301 286  HOH HOH F . 
Y  4 HOH 102 302 274  HOH HOH F . 
Y  4 HOH 103 303 272  HOH HOH F . 
Y  4 HOH 104 304 422  HOH HOH F . 
Y  4 HOH 105 305 881  HOH HOH F . 
Y  4 HOH 106 306 755  HOH HOH F . 
Y  4 HOH 107 307 772  HOH HOH F . 
Y  4 HOH 108 308 1193 HOH HOH F . 
Y  4 HOH 109 309 335  HOH HOH F . 
Y  4 HOH 110 310 1183 HOH HOH F . 
Y  4 HOH 111 311 982  HOH HOH F . 
Y  4 HOH 112 312 371  HOH HOH F . 
Y  4 HOH 113 313 191  HOH HOH F . 
Y  4 HOH 114 314 851  HOH HOH F . 
Y  4 HOH 115 315 187  HOH HOH F . 
Y  4 HOH 116 316 138  HOH HOH F . 
Y  4 HOH 117 317 564  HOH HOH F . 
Y  4 HOH 118 318 151  HOH HOH F . 
Y  4 HOH 119 319 681  HOH HOH F . 
Y  4 HOH 120 320 424  HOH HOH F . 
Y  4 HOH 121 321 282  HOH HOH F . 
Y  4 HOH 122 322 1110 HOH HOH F . 
Y  4 HOH 123 323 495  HOH HOH F . 
Y  4 HOH 124 324 921  HOH HOH F . 
Y  4 HOH 125 325 457  HOH HOH F . 
Y  4 HOH 126 326 661  HOH HOH F . 
Y  4 HOH 127 327 947  HOH HOH F . 
Y  4 HOH 128 328 799  HOH HOH F . 
Y  4 HOH 129 329 276  HOH HOH F . 
Y  4 HOH 130 330 308  HOH HOH F . 
Y  4 HOH 131 331 682  HOH HOH F . 
Y  4 HOH 132 332 606  HOH HOH F . 
Y  4 HOH 133 333 502  HOH HOH F . 
Y  4 HOH 134 334 677  HOH HOH F . 
Z  4 HOH 1   201 548  HOH HOH D . 
Z  4 HOH 2   202 952  HOH HOH D . 
Z  4 HOH 3   203 24   HOH HOH D . 
Z  4 HOH 4   204 717  HOH HOH D . 
Z  4 HOH 5   205 1169 HOH HOH D . 
Z  4 HOH 6   206 394  HOH HOH D . 
Z  4 HOH 7   207 996  HOH HOH D . 
Z  4 HOH 8   208 792  HOH HOH D . 
Z  4 HOH 9   209 884  HOH HOH D . 
Z  4 HOH 10  210 969  HOH HOH D . 
Z  4 HOH 11  211 874  HOH HOH D . 
Z  4 HOH 12  212 627  HOH HOH D . 
Z  4 HOH 13  213 206  HOH HOH D . 
Z  4 HOH 14  214 16   HOH HOH D . 
Z  4 HOH 15  215 555  HOH HOH D . 
Z  4 HOH 16  216 193  HOH HOH D . 
Z  4 HOH 17  217 62   HOH HOH D . 
Z  4 HOH 18  218 159  HOH HOH D . 
Z  4 HOH 19  219 516  HOH HOH D . 
Z  4 HOH 20  220 1139 HOH HOH D . 
Z  4 HOH 21  221 483  HOH HOH D . 
Z  4 HOH 22  222 102  HOH HOH D . 
Z  4 HOH 23  223 145  HOH HOH D . 
Z  4 HOH 24  224 487  HOH HOH D . 
Z  4 HOH 25  225 494  HOH HOH D . 
Z  4 HOH 26  226 105  HOH HOH D . 
Z  4 HOH 27  227 2    HOH HOH D . 
Z  4 HOH 28  228 53   HOH HOH D . 
Z  4 HOH 29  229 537  HOH HOH D . 
Z  4 HOH 30  230 178  HOH HOH D . 
Z  4 HOH 31  231 42   HOH HOH D . 
Z  4 HOH 32  232 318  HOH HOH D . 
Z  4 HOH 33  233 97   HOH HOH D . 
Z  4 HOH 34  234 210  HOH HOH D . 
Z  4 HOH 35  235 98   HOH HOH D . 
Z  4 HOH 36  236 107  HOH HOH D . 
Z  4 HOH 37  237 117  HOH HOH D . 
Z  4 HOH 38  238 823  HOH HOH D . 
Z  4 HOH 39  239 76   HOH HOH D . 
Z  4 HOH 40  240 345  HOH HOH D . 
Z  4 HOH 41  241 355  HOH HOH D . 
Z  4 HOH 42  242 265  HOH HOH D . 
Z  4 HOH 43  243 395  HOH HOH D . 
Z  4 HOH 44  244 939  HOH HOH D . 
Z  4 HOH 45  245 353  HOH HOH D . 
Z  4 HOH 46  246 903  HOH HOH D . 
Z  4 HOH 47  247 143  HOH HOH D . 
Z  4 HOH 48  248 366  HOH HOH D . 
Z  4 HOH 49  249 384  HOH HOH D . 
Z  4 HOH 50  250 601  HOH HOH D . 
Z  4 HOH 51  251 320  HOH HOH D . 
Z  4 HOH 52  252 570  HOH HOH D . 
Z  4 HOH 53  253 95   HOH HOH D . 
Z  4 HOH 54  254 279  HOH HOH D . 
Z  4 HOH 55  255 343  HOH HOH D . 
Z  4 HOH 56  256 26   HOH HOH D . 
Z  4 HOH 57  257 577  HOH HOH D . 
Z  4 HOH 58  258 55   HOH HOH D . 
Z  4 HOH 59  259 113  HOH HOH D . 
Z  4 HOH 60  260 174  HOH HOH D . 
Z  4 HOH 61  261 133  HOH HOH D . 
Z  4 HOH 62  262 619  HOH HOH D . 
Z  4 HOH 63  263 1080 HOH HOH D . 
Z  4 HOH 64  264 12   HOH HOH D . 
Z  4 HOH 65  265 563  HOH HOH D . 
Z  4 HOH 66  266 679  HOH HOH D . 
Z  4 HOH 67  267 887  HOH HOH D . 
Z  4 HOH 68  268 199  HOH HOH D . 
Z  4 HOH 69  269 333  HOH HOH D . 
Z  4 HOH 70  270 247  HOH HOH D . 
Z  4 HOH 71  271 103  HOH HOH D . 
Z  4 HOH 72  272 304  HOH HOH D . 
Z  4 HOH 73  273 141  HOH HOH D . 
Z  4 HOH 74  274 299  HOH HOH D . 
Z  4 HOH 75  275 798  HOH HOH D . 
Z  4 HOH 76  276 89   HOH HOH D . 
Z  4 HOH 77  277 156  HOH HOH D . 
Z  4 HOH 78  278 765  HOH HOH D . 
Z  4 HOH 79  279 376  HOH HOH D . 
Z  4 HOH 80  280 518  HOH HOH D . 
Z  4 HOH 81  281 287  HOH HOH D . 
Z  4 HOH 82  282 208  HOH HOH D . 
Z  4 HOH 83  283 312  HOH HOH D . 
Z  4 HOH 84  284 182  HOH HOH D . 
Z  4 HOH 85  285 978  HOH HOH D . 
Z  4 HOH 86  286 802  HOH HOH D . 
Z  4 HOH 87  287 56   HOH HOH D . 
Z  4 HOH 88  288 232  HOH HOH D . 
Z  4 HOH 89  289 1177 HOH HOH D . 
Z  4 HOH 90  290 101  HOH HOH D . 
Z  4 HOH 91  291 972  HOH HOH D . 
Z  4 HOH 92  292 534  HOH HOH D . 
Z  4 HOH 93  293 511  HOH HOH D . 
Z  4 HOH 94  294 22   HOH HOH D . 
Z  4 HOH 95  295 955  HOH HOH D . 
Z  4 HOH 96  296 916  HOH HOH D . 
Z  4 HOH 97  297 831  HOH HOH D . 
Z  4 HOH 98  298 211  HOH HOH D . 
Z  4 HOH 99  299 929  HOH HOH D . 
Z  4 HOH 100 300 669  HOH HOH D . 
Z  4 HOH 101 301 124  HOH HOH D . 
Z  4 HOH 102 302 349  HOH HOH D . 
Z  4 HOH 103 303 787  HOH HOH D . 
Z  4 HOH 104 304 900  HOH HOH D . 
Z  4 HOH 105 305 429  HOH HOH D . 
Z  4 HOH 106 306 528  HOH HOH D . 
Z  4 HOH 107 307 493  HOH HOH D . 
Z  4 HOH 108 308 181  HOH HOH D . 
Z  4 HOH 109 309 545  HOH HOH D . 
Z  4 HOH 110 310 1212 HOH HOH D . 
Z  4 HOH 111 311 297  HOH HOH D . 
Z  4 HOH 112 312 432  HOH HOH D . 
Z  4 HOH 113 313 687  HOH HOH D . 
Z  4 HOH 114 314 878  HOH HOH D . 
Z  4 HOH 115 315 879  HOH HOH D . 
Z  4 HOH 116 316 664  HOH HOH D . 
Z  4 HOH 117 317 840  HOH HOH D . 
Z  4 HOH 118 318 1238 HOH HOH D . 
Z  4 HOH 119 319 219  HOH HOH D . 
Z  4 HOH 120 320 636  HOH HOH D . 
Z  4 HOH 121 321 622  HOH HOH D . 
Z  4 HOH 122 322 412  HOH HOH D . 
Z  4 HOH 123 323 379  HOH HOH D . 
Z  4 HOH 124 324 691  HOH HOH D . 
Z  4 HOH 125 325 442  HOH HOH D . 
Z  4 HOH 126 326 213  HOH HOH D . 
Z  4 HOH 127 327 643  HOH HOH D . 
Z  4 HOH 128 328 880  HOH HOH D . 
Z  4 HOH 129 329 385  HOH HOH D . 
Z  4 HOH 130 330 354  HOH HOH D . 
Z  4 HOH 131 331 913  HOH HOH D . 
AA 4 HOH 1   201 404  HOH HOH A . 
AA 4 HOH 2   202 808  HOH HOH A . 
AA 4 HOH 3   203 480  HOH HOH A . 
AA 4 HOH 4   204 1077 HOH HOH A . 
AA 4 HOH 5   205 29   HOH HOH A . 
AA 4 HOH 6   206 462  HOH HOH A . 
AA 4 HOH 7   207 898  HOH HOH A . 
AA 4 HOH 8   208 86   HOH HOH A . 
AA 4 HOH 9   209 827  HOH HOH A . 
AA 4 HOH 10  210 255  HOH HOH A . 
AA 4 HOH 11  211 892  HOH HOH A . 
AA 4 HOH 12  212 4    HOH HOH A . 
AA 4 HOH 13  213 1219 HOH HOH A . 
AA 4 HOH 14  214 100  HOH HOH A . 
AA 4 HOH 15  215 650  HOH HOH A . 
AA 4 HOH 16  216 1191 HOH HOH A . 
AA 4 HOH 17  217 1    HOH HOH A . 
AA 4 HOH 18  218 85   HOH HOH A . 
AA 4 HOH 19  219 31   HOH HOH A . 
AA 4 HOH 20  220 106  HOH HOH A . 
AA 4 HOH 21  221 1184 HOH HOH A . 
AA 4 HOH 22  222 281  HOH HOH A . 
AA 4 HOH 23  223 19   HOH HOH A . 
AA 4 HOH 24  224 61   HOH HOH A . 
AA 4 HOH 25  225 1202 HOH HOH A . 
AA 4 HOH 26  226 785  HOH HOH A . 
AA 4 HOH 27  227 374  HOH HOH A . 
AA 4 HOH 28  228 82   HOH HOH A . 
AA 4 HOH 29  229 284  HOH HOH A . 
AA 4 HOH 30  230 18   HOH HOH A . 
AA 4 HOH 31  231 839  HOH HOH A . 
AA 4 HOH 32  232 401  HOH HOH A . 
AA 4 HOH 33  233 33   HOH HOH A . 
AA 4 HOH 34  234 667  HOH HOH A . 
AA 4 HOH 35  235 417  HOH HOH A . 
AA 4 HOH 36  236 557  HOH HOH A . 
AA 4 HOH 37  237 228  HOH HOH A . 
AA 4 HOH 38  238 331  HOH HOH A . 
AA 4 HOH 39  239 1141 HOH HOH A . 
AA 4 HOH 40  240 290  HOH HOH A . 
AA 4 HOH 41  241 20   HOH HOH A . 
AA 4 HOH 42  242 1170 HOH HOH A . 
AA 4 HOH 43  243 937  HOH HOH A . 
AA 4 HOH 44  244 1221 HOH HOH A . 
AA 4 HOH 45  245 706  HOH HOH A . 
AA 4 HOH 46  246 172  HOH HOH A . 
AA 4 HOH 47  247 386  HOH HOH A . 
AA 4 HOH 48  248 666  HOH HOH A . 
AA 4 HOH 49  249 59   HOH HOH A . 
AA 4 HOH 50  250 565  HOH HOH A . 
AA 4 HOH 51  251 119  HOH HOH A . 
AA 4 HOH 52  252 531  HOH HOH A . 
AA 4 HOH 53  253 50   HOH HOH A . 
AA 4 HOH 54  254 364  HOH HOH A . 
AA 4 HOH 55  255 57   HOH HOH A . 
AA 4 HOH 56  256 770  HOH HOH A . 
AA 4 HOH 57  257 158  HOH HOH A . 
AA 4 HOH 58  258 342  HOH HOH A . 
AA 4 HOH 59  259 23   HOH HOH A . 
AA 4 HOH 60  260 323  HOH HOH A . 
AA 4 HOH 61  261 363  HOH HOH A . 
AA 4 HOH 62  262 558  HOH HOH A . 
AA 4 HOH 63  263 136  HOH HOH A . 
AA 4 HOH 64  264 44   HOH HOH A . 
AA 4 HOH 65  265 813  HOH HOH A . 
AA 4 HOH 66  266 901  HOH HOH A . 
AA 4 HOH 67  267 448  HOH HOH A . 
AA 4 HOH 68  268 94   HOH HOH A . 
AA 4 HOH 69  269 405  HOH HOH A . 
AA 4 HOH 70  270 188  HOH HOH A . 
AA 4 HOH 71  271 454  HOH HOH A . 
AA 4 HOH 72  272 30   HOH HOH A . 
AA 4 HOH 73  273 218  HOH HOH A . 
AA 4 HOH 74  274 1225 HOH HOH A . 
AA 4 HOH 75  275 111  HOH HOH A . 
AA 4 HOH 76  276 128  HOH HOH A . 
AA 4 HOH 77  277 842  HOH HOH A . 
AA 4 HOH 78  278 164  HOH HOH A . 
AA 4 HOH 79  279 70   HOH HOH A . 
AA 4 HOH 80  280 84   HOH HOH A . 
AA 4 HOH 81  281 328  HOH HOH A . 
AA 4 HOH 82  282 165  HOH HOH A . 
AA 4 HOH 83  283 54   HOH HOH A . 
AA 4 HOH 84  284 1176 HOH HOH A . 
AA 4 HOH 85  285 1227 HOH HOH A . 
AA 4 HOH 86  286 1072 HOH HOH A . 
AA 4 HOH 87  287 348  HOH HOH A . 
AA 4 HOH 88  288 273  HOH HOH A . 
AA 4 HOH 89  289 325  HOH HOH A . 
AA 4 HOH 90  290 977  HOH HOH A . 
AA 4 HOH 91  291 373  HOH HOH A . 
AA 4 HOH 92  292 897  HOH HOH A . 
AA 4 HOH 93  293 419  HOH HOH A . 
AA 4 HOH 94  294 1232 HOH HOH A . 
AA 4 HOH 95  295 1231 HOH HOH A . 
AA 4 HOH 96  296 591  HOH HOH A . 
AA 4 HOH 97  297 63   HOH HOH A . 
AA 4 HOH 98  298 443  HOH HOH A . 
AA 4 HOH 99  299 875  HOH HOH A . 
AA 4 HOH 100 300 1216 HOH HOH A . 
AA 4 HOH 101 301 192  HOH HOH A . 
AA 4 HOH 102 302 1186 HOH HOH A . 
AA 4 HOH 103 303 1188 HOH HOH A . 
AA 4 HOH 104 304 137  HOH HOH A . 
AA 4 HOH 105 305 668  HOH HOH A . 
AA 4 HOH 106 306 450  HOH HOH A . 
AA 4 HOH 107 307 775  HOH HOH A . 
AA 4 HOH 108 308 1209 HOH HOH A . 
AA 4 HOH 109 309 471  HOH HOH A . 
AA 4 HOH 110 310 852  HOH HOH A . 
AA 4 HOH 111 311 927  HOH HOH A . 
AA 4 HOH 112 312 919  HOH HOH A . 
AA 4 HOH 113 313 166  HOH HOH A . 
AA 4 HOH 114 314 296  HOH HOH A . 
AA 4 HOH 115 315 1155 HOH HOH A . 
AA 4 HOH 116 316 1187 HOH HOH A . 
AA 4 HOH 117 317 358  HOH HOH A . 
AA 4 HOH 118 318 477  HOH HOH A . 
AA 4 HOH 119 319 1189 HOH HOH A . 
AA 4 HOH 120 320 1222 HOH HOH A . 
AA 4 HOH 121 321 486  HOH HOH A . 
AA 4 HOH 122 322 1094 HOH HOH A . 
AA 4 HOH 123 323 291  HOH HOH A . 
AA 4 HOH 124 324 239  HOH HOH A . 
AA 4 HOH 125 325 169  HOH HOH A . 
AA 4 HOH 126 326 414  HOH HOH A . 
AA 4 HOH 127 327 819  HOH HOH A . 
AA 4 HOH 128 328 817  HOH HOH A . 
AA 4 HOH 129 329 561  HOH HOH A . 
AA 4 HOH 130 330 1133 HOH HOH A . 
AA 4 HOH 131 331 1233 HOH HOH A . 
AA 4 HOH 132 332 520  HOH HOH A . 
AA 4 HOH 133 333 498  HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 0 A THR 89 ? CA  ? F THR 91 CA  
2 1 Y 0 A THR 89 ? C   ? F THR 91 C   
3 1 Y 0 A THR 89 ? O   ? F THR 91 O   
4 1 Y 0 A THR 89 ? CB  ? F THR 91 CB  
5 1 Y 0 A THR 89 ? OG1 ? F THR 91 OG1 
6 1 Y 0 A THR 89 ? CG2 ? F THR 91 CG2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.21.1_5286 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.394 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GR4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     44.048 
_cell.length_a_esd                 ? 
_cell.length_b                     73.548 
_cell.length_b_esd                 ? 
_cell.length_c                     75.893 
_cell.length_c_esd                 ? 
_cell.volume                       245860.360 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GR4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GR4 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             1.98 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          38 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '20% PEG 3350, 0.15 M di-sodium DL-malate pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-07-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    M 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.980 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SOLEIL BEAMLINE PROXIMA 2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.980 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   'PROXIMA 2' 
_diffrn_source.pdbx_synchrotron_site       SOLEIL 
# 
_reflns.B_iso_Wilson_estimate                          9.48 
_reflns.entry_id                                       9GR4 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.077 
_reflns.d_resolution_low                               75.891 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     176082 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           84.4 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          22.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.043 
_reflns.pdbx_Rpim_I_all                                0.017 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.040 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.077 
_reflns_shell.d_res_low                                     1.095 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.4 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2849 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               1.8 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.362 
_reflns_shell.pdbx_Rpim_I_all                               0.244 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.863 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          27.4 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.266 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               14.52 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9GR4 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.08 
_refine.ls_d_res_low                             38.21 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     176059 
_refine.ls_number_reflns_R_free                  9059 
_refine.ls_number_reflns_R_work                  167000 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    84.40 
_refine.ls_percent_reflns_R_free                 5.15 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1625 
_refine.ls_R_factor_R_free                       0.1755 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1618 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.37 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 18.7092 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.0742 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.08 
_refine_hist.d_res_low                        38.21 
_refine_hist.number_atoms_solvent             796 
_refine_hist.number_atoms_total               5260 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4176 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         288 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0038  ? 4638 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.7718  ? 6429 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0739  ? 695  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0063  ? 750  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 10.2374 ? 1579 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.08 1.09  . . 81  1705 25.75 . . . . 0.2460 . . . . . . . . . . . 0.3271 
'X-RAY DIFFRACTION' 1.09 1.10  . . 99  2156 32.27 . . . . 0.2289 . . . . . . . . . . . 0.2264 
'X-RAY DIFFRACTION' 1.10 1.12  . . 144 2516 38.67 . . . . 0.2145 . . . . . . . . . . . 0.2569 
'X-RAY DIFFRACTION' 1.12 1.13  . . 174 3066 46.63 . . . . 0.1967 . . . . . . . . . . . 0.2242 
'X-RAY DIFFRACTION' 1.13 1.14  . . 169 3406 52.01 . . . . 0.1988 . . . . . . . . . . . 0.2111 
'X-RAY DIFFRACTION' 1.14 1.16  . . 260 3817 58.26 . . . . 0.1923 . . . . . . . . . . . 0.1920 
'X-RAY DIFFRACTION' 1.16 1.18  . . 238 4217 64.96 . . . . 0.1831 . . . . . . . . . . . 0.2026 
'X-RAY DIFFRACTION' 1.18 1.19  . . 270 4853 73.43 . . . . 0.1818 . . . . . . . . . . . 0.1926 
'X-RAY DIFFRACTION' 1.19 1.21  . . 275 5487 83.74 . . . . 0.1838 . . . . . . . . . . . 0.2070 
'X-RAY DIFFRACTION' 1.21 1.23  . . 321 6157 93.05 . . . . 0.1848 . . . . . . . . . . . 0.1764 
'X-RAY DIFFRACTION' 1.23 1.25  . . 265 6364 95.96 . . . . 0.1769 . . . . . . . . . . . 0.1942 
'X-RAY DIFFRACTION' 1.25 1.28  . . 358 6362 96.69 . . . . 0.1753 . . . . . . . . . . . 0.1798 
'X-RAY DIFFRACTION' 1.28 1.30  . . 331 6431 96.82 . . . . 0.1732 . . . . . . . . . . . 0.2030 
'X-RAY DIFFRACTION' 1.30 1.33  . . 412 6305 97.00 . . . . 0.1725 . . . . . . . . . . . 0.1794 
'X-RAY DIFFRACTION' 1.33 1.36  . . 356 6390 97.39 . . . . 0.1720 . . . . . . . . . . . 0.1862 
'X-RAY DIFFRACTION' 1.36 1.39  . . 334 6415 97.42 . . . . 0.1735 . . . . . . . . . . . 0.1765 
'X-RAY DIFFRACTION' 1.39 1.42  . . 314 6487 97.74 . . . . 0.1699 . . . . . . . . . . . 0.1844 
'X-RAY DIFFRACTION' 1.42 1.46  . . 375 6405 97.76 . . . . 0.1713 . . . . . . . . . . . 0.1866 
'X-RAY DIFFRACTION' 1.46 1.50  . . 327 6526 98.17 . . . . 0.1666 . . . . . . . . . . . 0.1820 
'X-RAY DIFFRACTION' 1.50 1.55  . . 360 6443 98.31 . . . . 0.1638 . . . . . . . . . . . 0.1794 
'X-RAY DIFFRACTION' 1.55 1.61  . . 371 6466 98.46 . . . . 0.1622 . . . . . . . . . . . 0.1725 
'X-RAY DIFFRACTION' 1.61 1.67  . . 348 6514 98.66 . . . . 0.1573 . . . . . . . . . . . 0.1834 
'X-RAY DIFFRACTION' 1.67 1.75  . . 394 6502 98.81 . . . . 0.1624 . . . . . . . . . . . 0.1648 
'X-RAY DIFFRACTION' 1.75 1.84  . . 449 6456 99.15 . . . . 0.1641 . . . . . . . . . . . 0.1844 
'X-RAY DIFFRACTION' 1.84 1.96  . . 330 6566 99.37 . . . . 0.1580 . . . . . . . . . . . 0.1760 
'X-RAY DIFFRACTION' 1.96 2.11  . . 376 6582 99.57 . . . . 0.1582 . . . . . . . . . . . 0.1758 
'X-RAY DIFFRACTION' 2.11 2.32  . . 353 6616 99.66 . . . . 0.1574 . . . . . . . . . . . 0.1734 
'X-RAY DIFFRACTION' 2.32 2.65  . . 326 6621 99.71 . . . . 0.1634 . . . . . . . . . . . 0.1797 
'X-RAY DIFFRACTION' 2.65 3.34  . . 325 6673 99.72 . . . . 0.1515 . . . . . . . . . . . 0.1670 
'X-RAY DIFFRACTION' 3.34 38.21 . . 324 6496 95.83 . . . . 0.1428 . . . . . . . . . . . 0.1460 
# 
_struct.entry_id                     9GR4 
_struct.title                        'The MKA-RSL - sulfonato-calix[4]arene complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GR4 
_struct_keywords.text            'Beta-propeller, lectin, trimer, SUGAR BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'SUGAR BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A  N N 1 ? 
B  N N 1 ? 
C  N N 1 ? 
D  N N 1 ? 
E  N N 1 ? 
F  N N 1 ? 
G  N N 2 ? 
H  N N 2 ? 
I  N N 3 ? 
J  N N 2 ? 
K  N N 2 ? 
L  N N 3 ? 
M  N N 2 ? 
N  N N 2 ? 
O  N N 2 ? 
P  N N 2 ? 
Q  N N 2 ? 
R  N N 2 ? 
S  N N 3 ? 
T  N N 2 ? 
U  N N 2 ? 
V  N N 4 ? 
W  N N 4 ? 
X  N N 4 ? 
Y  N N 4 ? 
Z  N N 4 ? 
AA N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A0S4TLR1_RALSL 
_struct_ref.pdbx_db_accession          A0A0S4TLR1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNG
WTKGAYTATN
;
_struct_ref.pdbx_align_begin           2 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9GR4 B 3 ? 92 ? A0A0S4TLR1 2 ? 91 ? 1 90 
2 1 9GR4 C 3 ? 92 ? A0A0S4TLR1 2 ? 91 ? 1 90 
3 1 9GR4 E 3 ? 92 ? A0A0S4TLR1 2 ? 91 ? 1 90 
4 1 9GR4 F 3 ? 92 ? A0A0S4TLR1 2 ? 91 ? 1 90 
5 1 9GR4 D 3 ? 92 ? A0A0S4TLR1 2 ? 91 ? 1 90 
6 1 9GR4 A 3 ? 92 ? A0A0S4TLR1 2 ? 91 ? 1 90 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9GR4 MET B 1 ? UNP A0A0S4TLR1 ?   ? 'initiating methionine' -1 1  
1 9GR4 LYS B 2 ? UNP A0A0S4TLR1 ?   ? 'expression tag'        0  2  
1 9GR4 ALA B 3 ? UNP A0A0S4TLR1 SER 2 'engineered mutation'   1  3  
2 9GR4 MET C 1 ? UNP A0A0S4TLR1 ?   ? 'initiating methionine' -1 4  
2 9GR4 LYS C 2 ? UNP A0A0S4TLR1 ?   ? 'expression tag'        0  5  
2 9GR4 ALA C 3 ? UNP A0A0S4TLR1 SER 2 'engineered mutation'   1  6  
3 9GR4 MET E 1 ? UNP A0A0S4TLR1 ?   ? 'initiating methionine' -1 7  
3 9GR4 LYS E 2 ? UNP A0A0S4TLR1 ?   ? 'expression tag'        0  8  
3 9GR4 ALA E 3 ? UNP A0A0S4TLR1 SER 2 'engineered mutation'   1  9  
4 9GR4 MET F 1 ? UNP A0A0S4TLR1 ?   ? 'initiating methionine' -1 10 
4 9GR4 LYS F 2 ? UNP A0A0S4TLR1 ?   ? 'expression tag'        0  11 
4 9GR4 ALA F 3 ? UNP A0A0S4TLR1 SER 2 'engineered mutation'   1  12 
5 9GR4 MET D 1 ? UNP A0A0S4TLR1 ?   ? 'initiating methionine' -1 13 
5 9GR4 LYS D 2 ? UNP A0A0S4TLR1 ?   ? 'expression tag'        0  14 
5 9GR4 ALA D 3 ? UNP A0A0S4TLR1 SER 2 'engineered mutation'   1  15 
6 9GR4 MET A 1 ? UNP A0A0S4TLR1 ?   ? 'initiating methionine' -1 16 
6 9GR4 LYS A 2 ? UNP A0A0S4TLR1 ?   ? 'expression tag'        0  17 
6 9GR4 ALA A 3 ? UNP A0A0S4TLR1 SER 2 'engineered mutation'   1  18 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? trimeric 3 
2 author_defined_assembly ? trimeric 3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 6990  ? 
1 MORE         -19   ? 
1 'SSA (A^2)'  12810 ? 
2 'ABSA (A^2)' 7060  ? 
2 MORE         -19   ? 
2 'SSA (A^2)'  12000 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,C,G,H,I,J,K,L,M,N,V,W,X 
2 1 D,E,F,O,P,Q,R,S,T,U,Y,Z,AA  
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 VAL 15 A . ? VAL 13 B PRO 16 A ? PRO 14 B 1 -7.73 
2 VAL 15 B . ? VAL 13 C PRO 16 B ? PRO 14 C 1 -6.70 
3 VAL 15 C . ? VAL 13 E PRO 16 C ? PRO 14 E 1 -4.70 
4 VAL 15 D . ? VAL 13 F PRO 16 D ? PRO 14 F 1 -6.10 
5 VAL 15 E . ? VAL 13 D PRO 16 E ? PRO 14 D 1 -6.41 
6 VAL 15 F . ? VAL 13 A PRO 16 F ? PRO 14 A 1 -8.13 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 6  ? TRP A 12 ? GLN B 4  TRP B 10 
AA1 2 SER A 17 ? ASN A 24 ? SER B 15 ASN B 22 
AA1 3 LYS A 27 ? TRP A 33 ? LYS B 25 TRP B 31 
AA1 4 TYR A 39 ? PRO A 46 ? TYR B 37 PRO B 44 
AA2 1 ASN A 49 ? VAL A 57 ? ASN B 47 VAL B 55 
AA2 2 ALA A 60 ? THR A 69 ? ALA B 58 THR B 67 
AA2 3 THR A 72 ? TRP A 78 ? THR B 70 TRP B 76 
AA2 4 TRP A 83 ? LYS A 85 ? TRP B 81 LYS B 83 
AA3 1 GLN B 6  ? TRP B 12 ? GLN C 4  TRP C 10 
AA3 2 SER B 17 ? ASN B 24 ? SER C 15 ASN C 22 
AA3 3 LYS B 27 ? TRP B 33 ? LYS C 25 TRP C 31 
AA3 4 TRP B 38 ? PRO B 46 ? TRP C 36 PRO C 44 
AA4 1 ASN B 49 ? VAL B 57 ? ASN C 47 VAL C 55 
AA4 2 ALA B 60 ? THR B 69 ? ALA C 58 THR C 67 
AA4 3 THR B 72 ? TRP B 78 ? THR C 70 TRP C 76 
AA4 4 TRP B 83 ? LYS B 85 ? TRP C 81 LYS C 83 
AA5 1 GLN C 6  ? TRP C 12 ? GLN E 4  TRP E 10 
AA5 2 SER C 17 ? ASN C 24 ? SER E 15 ASN E 22 
AA5 3 LYS C 27 ? TRP C 33 ? LYS E 25 TRP E 31 
AA5 4 TRP C 38 ? PRO C 46 ? TRP E 36 PRO E 44 
AA6 1 ASN C 49 ? VAL C 57 ? ASN E 47 VAL E 55 
AA6 2 ALA C 60 ? THR C 69 ? ALA E 58 THR E 67 
AA6 3 THR C 72 ? TRP C 78 ? THR E 70 TRP E 76 
AA6 4 TRP C 83 ? LYS C 85 ? TRP E 81 LYS E 83 
AA7 1 GLN D 6  ? TRP D 12 ? GLN F 4  TRP F 10 
AA7 2 SER D 17 ? ASN D 24 ? SER F 15 ASN F 22 
AA7 3 LYS D 27 ? TRP D 33 ? LYS F 25 TRP F 31 
AA7 4 TRP D 38 ? PRO D 46 ? TRP F 36 PRO F 44 
AA8 1 ASN D 49 ? VAL D 57 ? ASN F 47 VAL F 55 
AA8 2 ALA D 60 ? THR D 69 ? ALA F 58 THR F 67 
AA8 3 THR D 72 ? TRP D 78 ? THR F 70 TRP F 76 
AA8 4 TRP D 83 ? LYS D 85 ? TRP F 81 LYS F 83 
AA9 1 GLN E 6  ? TRP E 12 ? GLN D 4  TRP D 10 
AA9 2 SER E 17 ? ASN E 24 ? SER D 15 ASN D 22 
AA9 3 LYS E 27 ? TRP E 33 ? LYS D 25 TRP D 31 
AA9 4 TRP E 38 ? PRO E 46 ? TRP D 36 PRO D 44 
AB1 1 ASN E 49 ? VAL E 57 ? ASN D 47 VAL D 55 
AB1 2 ALA E 60 ? THR E 69 ? ALA D 58 THR D 67 
AB1 3 THR E 72 ? TRP E 78 ? THR D 70 TRP D 76 
AB1 4 TRP E 83 ? LYS E 85 ? TRP D 81 LYS D 83 
AB2 1 GLN F 6  ? TRP F 12 ? GLN A 4  TRP A 10 
AB2 2 SER F 17 ? ASN F 24 ? SER A 15 ASN A 22 
AB2 3 LYS F 27 ? TRP F 33 ? LYS A 25 TRP A 31 
AB2 4 TRP F 38 ? PRO F 46 ? TRP A 36 PRO A 44 
AB3 1 ASN F 49 ? VAL F 57 ? ASN A 47 VAL A 55 
AB3 2 ALA F 60 ? THR F 69 ? ALA A 58 THR A 67 
AB3 3 THR F 72 ? TRP F 78 ? THR A 70 TRP A 76 
AB3 4 TRP F 83 ? LYS F 85 ? TRP A 81 LYS A 83 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 6  ? N GLN B 4  O ALA A 23 ? O ALA B 21 
AA1 2 3 N ASN A 24 ? N ASN B 22 O LYS A 27 ? O LYS B 25 
AA1 3 4 N CYS A 32 ? N CYS B 30 O TYR A 39 ? O TYR B 37 
AA2 1 2 N THR A 53 ? N THR B 51 O ARG A 64 ? O ARG B 62 
AA2 2 3 N ALA A 67 ? N ALA B 65 O THR A 74 ? O THR B 72 
AA2 3 4 N CYS A 77 ? N CYS B 75 O THR A 84 ? O THR B 82 
AA3 1 2 N GLN B 6  ? N GLN C 4  O ALA B 23 ? O ALA C 21 
AA3 2 3 N ILE B 18 ? N ILE C 16 O TRP B 33 ? O TRP C 31 
AA3 3 4 N CYS B 32 ? N CYS C 30 O TYR B 39 ? O TYR C 37 
AA4 1 2 N THR B 53 ? N THR C 51 O ARG B 64 ? O ARG C 62 
AA4 2 3 N ALA B 67 ? N ALA C 65 O THR B 74 ? O THR C 72 
AA4 3 4 N CYS B 77 ? N CYS C 75 O THR B 84 ? O THR C 82 
AA5 1 2 N GLN C 6  ? N GLN E 4  O ALA C 23 ? O ALA E 21 
AA5 2 3 N ASN C 24 ? N ASN E 22 O LYS C 27 ? O LYS E 25 
AA5 3 4 N ILE C 28 ? N ILE E 26 O GLU C 45 ? O GLU E 43 
AA6 1 2 N THR C 53 ? N THR E 51 O ARG C 64 ? O ARG E 62 
AA6 2 3 N ALA C 67 ? N ALA E 65 O THR C 74 ? O THR E 72 
AA6 3 4 N CYS C 77 ? N CYS E 75 O THR C 84 ? O THR E 82 
AA7 1 2 N ALA D 8  ? N ALA F 6  O TYR D 21 ? O TYR F 19 
AA7 2 3 N ASN D 24 ? N ASN F 22 O LYS D 27 ? O LYS F 25 
AA7 3 4 N CYS D 32 ? N CYS F 30 O TYR D 39 ? O TYR F 37 
AA8 1 2 N THR D 53 ? N THR F 51 O ARG D 64 ? O ARG F 62 
AA8 2 3 N ALA D 67 ? N ALA F 65 O THR D 74 ? O THR F 72 
AA8 3 4 N CYS D 77 ? N CYS F 75 O THR D 84 ? O THR F 82 
AA9 1 2 N ALA E 8  ? N ALA D 6  O TYR E 21 ? O TYR D 19 
AA9 2 3 N ASN E 24 ? N ASN D 22 O LYS E 27 ? O LYS D 25 
AA9 3 4 N CYS E 32 ? N CYS D 30 O TYR E 39 ? O TYR D 37 
AB1 1 2 N THR E 53 ? N THR D 51 O ARG E 64 ? O ARG D 62 
AB1 2 3 N ALA E 67 ? N ALA D 65 O THR E 74 ? O THR D 72 
AB1 3 4 N CYS E 77 ? N CYS D 75 O THR E 84 ? O THR D 82 
AB2 1 2 N GLN F 6  ? N GLN A 4  O ALA F 23 ? O ALA A 21 
AB2 2 3 N ASN F 24 ? N ASN A 22 O LYS F 27 ? O LYS A 25 
AB2 3 4 N CYS F 32 ? N CYS A 30 O TYR F 39 ? O TYR A 37 
AB3 1 2 N THR F 53 ? N THR A 51 O ARG F 64 ? O ARG A 62 
AB3 2 3 N ALA F 67 ? N ALA A 65 O THR F 74 ? O THR A 72 
AB3 3 4 N CYS F 77 ? N CYS A 75 O THR F 84 ? O THR A 82 
# 
_pdbx_entry_details.entry_id                   9GR4 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS B 34 ? ? -146.98 46.43  
2  1 SER C 2  ? ? -170.97 125.20 
3  1 LYS C 34 ? ? -142.34 27.17  
4  1 ASN E 79 ? ? -147.29 52.98  
5  1 THR E 89 ? ? -108.83 77.99  
6  1 LYS F 34 ? ? -142.56 43.00  
7  1 ASN F 79 ? ? -148.26 56.13  
8  1 LYS D 34 ? ? -141.03 38.01  
9  1 ASN D 79 ? ? -152.48 54.76  
10 1 ALA A 1  ? ? 68.10   -64.96 
11 1 ASN A 79 ? ? -147.64 56.89  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? C HOH 339 ? 6.19 . 
2 1 O ? E HOH 342 ? 6.02 . 
3 1 O ? E HOH 343 ? 6.18 . 
4 1 O ? F HOH 334 ? 6.08 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 E MET -1 ? C MET 1  
2 1 Y 1 F MET -1 ? D MET 1  
3 1 Y 1 F LYS 0  ? D LYS 2  
4 1 Y 1 D MET -1 ? E MET 1  
5 1 Y 1 D LYS 0  ? E LYS 2  
6 1 Y 0 A ASN 90 ? F ASN 92 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BDF C1   C N N 74  
BDF C2   C N R 75  
BDF C3   C N S 76  
BDF C4   C N R 77  
BDF C5   C N R 78  
BDF C6   C N N 79  
BDF O1   O N N 80  
BDF O2   O N N 81  
BDF O3   O N N 82  
BDF O4   O N N 83  
BDF O5   O N N 84  
BDF O6   O N N 85  
BDF H11  H N N 86  
BDF H12  H N N 87  
BDF H3   H N N 88  
BDF H4   H N N 89  
BDF H5   H N N 90  
BDF H61  H N N 91  
BDF H62  H N N 92  
BDF HO1  H N N 93  
BDF HO2  H N N 94  
BDF HO3  H N N 95  
BDF HO4  H N N 96  
BDF HO5  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
GLN N    N N N 112 
GLN CA   C N S 113 
GLN C    C N N 114 
GLN O    O N N 115 
GLN CB   C N N 116 
GLN CG   C N N 117 
GLN CD   C N N 118 
GLN OE1  O N N 119 
GLN NE2  N N N 120 
GLN OXT  O N N 121 
GLN H    H N N 122 
GLN H2   H N N 123 
GLN HA   H N N 124 
GLN HB2  H N N 125 
GLN HB3  H N N 126 
GLN HG2  H N N 127 
GLN HG3  H N N 128 
GLN HE21 H N N 129 
GLN HE22 H N N 130 
GLN HXT  H N N 131 
GLU N    N N N 132 
GLU CA   C N S 133 
GLU C    C N N 134 
GLU O    O N N 135 
GLU CB   C N N 136 
GLU CG   C N N 137 
GLU CD   C N N 138 
GLU OE1  O N N 139 
GLU OE2  O N N 140 
GLU OXT  O N N 141 
GLU H    H N N 142 
GLU H2   H N N 143 
GLU HA   H N N 144 
GLU HB2  H N N 145 
GLU HB3  H N N 146 
GLU HG2  H N N 147 
GLU HG3  H N N 148 
GLU HE2  H N N 149 
GLU HXT  H N N 150 
GLY N    N N N 151 
GLY CA   C N N 152 
GLY C    C N N 153 
GLY O    O N N 154 
GLY OXT  O N N 155 
GLY H    H N N 156 
GLY H2   H N N 157 
GLY HA2  H N N 158 
GLY HA3  H N N 159 
GLY HXT  H N N 160 
HIS N    N N N 161 
HIS CA   C N S 162 
HIS C    C N N 163 
HIS O    O N N 164 
HIS CB   C N N 165 
HIS CG   C Y N 166 
HIS ND1  N Y N 167 
HIS CD2  C Y N 168 
HIS CE1  C Y N 169 
HIS NE2  N Y N 170 
HIS OXT  O N N 171 
HIS H    H N N 172 
HIS H2   H N N 173 
HIS HA   H N N 174 
HIS HB2  H N N 175 
HIS HB3  H N N 176 
HIS HD1  H N N 177 
HIS HD2  H N N 178 
HIS HE1  H N N 179 
HIS HE2  H N N 180 
HIS HXT  H N N 181 
HOH O    O N N 182 
HOH H1   H N N 183 
HOH H2   H N N 184 
ILE N    N N N 185 
ILE CA   C N S 186 
ILE C    C N N 187 
ILE O    O N N 188 
ILE CB   C N S 189 
ILE CG1  C N N 190 
ILE CG2  C N N 191 
ILE CD1  C N N 192 
ILE OXT  O N N 193 
ILE H    H N N 194 
ILE H2   H N N 195 
ILE HA   H N N 196 
ILE HB   H N N 197 
ILE HG12 H N N 198 
ILE HG13 H N N 199 
ILE HG21 H N N 200 
ILE HG22 H N N 201 
ILE HG23 H N N 202 
ILE HD11 H N N 203 
ILE HD12 H N N 204 
ILE HD13 H N N 205 
ILE HXT  H N N 206 
LEU N    N N N 207 
LEU CA   C N S 208 
LEU C    C N N 209 
LEU O    O N N 210 
LEU CB   C N N 211 
LEU CG   C N N 212 
LEU CD1  C N N 213 
LEU CD2  C N N 214 
LEU OXT  O N N 215 
LEU H    H N N 216 
LEU H2   H N N 217 
LEU HA   H N N 218 
LEU HB2  H N N 219 
LEU HB3  H N N 220 
LEU HG   H N N 221 
LEU HD11 H N N 222 
LEU HD12 H N N 223 
LEU HD13 H N N 224 
LEU HD21 H N N 225 
LEU HD22 H N N 226 
LEU HD23 H N N 227 
LEU HXT  H N N 228 
LYS N    N N N 229 
LYS CA   C N S 230 
LYS C    C N N 231 
LYS O    O N N 232 
LYS CB   C N N 233 
LYS CG   C N N 234 
LYS CD   C N N 235 
LYS CE   C N N 236 
LYS NZ   N N N 237 
LYS OXT  O N N 238 
LYS H    H N N 239 
LYS H2   H N N 240 
LYS HA   H N N 241 
LYS HB2  H N N 242 
LYS HB3  H N N 243 
LYS HG2  H N N 244 
LYS HG3  H N N 245 
LYS HD2  H N N 246 
LYS HD3  H N N 247 
LYS HE2  H N N 248 
LYS HE3  H N N 249 
LYS HZ1  H N N 250 
LYS HZ2  H N N 251 
LYS HZ3  H N N 252 
LYS HXT  H N N 253 
MET N    N N N 254 
MET CA   C N S 255 
MET C    C N N 256 
MET O    O N N 257 
MET CB   C N N 258 
MET CG   C N N 259 
MET SD   S N N 260 
MET CE   C N N 261 
MET OXT  O N N 262 
MET H    H N N 263 
MET H2   H N N 264 
MET HA   H N N 265 
MET HB2  H N N 266 
MET HB3  H N N 267 
MET HG2  H N N 268 
MET HG3  H N N 269 
MET HE1  H N N 270 
MET HE2  H N N 271 
MET HE3  H N N 272 
MET HXT  H N N 273 
PHE N    N N N 274 
PHE CA   C N S 275 
PHE C    C N N 276 
PHE O    O N N 277 
PHE CB   C N N 278 
PHE CG   C Y N 279 
PHE CD1  C Y N 280 
PHE CD2  C Y N 281 
PHE CE1  C Y N 282 
PHE CE2  C Y N 283 
PHE CZ   C Y N 284 
PHE OXT  O N N 285 
PHE H    H N N 286 
PHE H2   H N N 287 
PHE HA   H N N 288 
PHE HB2  H N N 289 
PHE HB3  H N N 290 
PHE HD1  H N N 291 
PHE HD2  H N N 292 
PHE HE1  H N N 293 
PHE HE2  H N N 294 
PHE HZ   H N N 295 
PHE HXT  H N N 296 
PRO N    N N N 297 
PRO CA   C N S 298 
PRO C    C N N 299 
PRO O    O N N 300 
PRO CB   C N N 301 
PRO CG   C N N 302 
PRO CD   C N N 303 
PRO OXT  O N N 304 
PRO H    H N N 305 
PRO HA   H N N 306 
PRO HB2  H N N 307 
PRO HB3  H N N 308 
PRO HG2  H N N 309 
PRO HG3  H N N 310 
PRO HD2  H N N 311 
PRO HD3  H N N 312 
PRO HXT  H N N 313 
SER N    N N N 314 
SER CA   C N S 315 
SER C    C N N 316 
SER O    O N N 317 
SER CB   C N N 318 
SER OG   O N N 319 
SER OXT  O N N 320 
SER H    H N N 321 
SER H2   H N N 322 
SER HA   H N N 323 
SER HB2  H N N 324 
SER HB3  H N N 325 
SER HG   H N N 326 
SER HXT  H N N 327 
T3Y O3   O N N 328 
T3Y S1   S N N 329 
T3Y O1   O N N 330 
T3Y O2   O N N 331 
T3Y C1   C Y N 332 
T3Y C24  C Y N 333 
T3Y C23  C Y N 334 
T3Y C22  C N N 335 
T3Y C2   C Y N 336 
T3Y C3   C Y N 337 
T3Y C25  C Y N 338 
T3Y O13  O N N 339 
T3Y C4   C N N 340 
T3Y C5   C Y N 341 
T3Y C6   C Y N 342 
T3Y C7   C Y N 343 
T3Y S2   S N N 344 
T3Y O4   O N N 345 
T3Y O5   O N N 346 
T3Y O6   O N N 347 
T3Y C8   C Y N 348 
T3Y C28  C Y N 349 
T3Y O16  O N N 350 
T3Y C9   C Y N 351 
T3Y C10  C N N 352 
T3Y C11  C Y N 353 
T3Y C12  C Y N 354 
T3Y C13  C Y N 355 
T3Y S3   S N N 356 
T3Y O7   O N N 357 
T3Y O8   O N N 358 
T3Y O9   O N N 359 
T3Y C14  C Y N 360 
T3Y C27  C Y N 361 
T3Y O15  O N N 362 
T3Y C15  C Y N 363 
T3Y C16  C N N 364 
T3Y C17  C Y N 365 
T3Y C18  C Y N 366 
T3Y C26  C Y N 367 
T3Y O14  O N N 368 
T3Y C21  C Y N 369 
T3Y C20  C Y N 370 
T3Y C19  C Y N 371 
T3Y S4   S N N 372 
T3Y O11  O N N 373 
T3Y O10  O N N 374 
T3Y O12  O N N 375 
T3Y HO3  H N N 376 
T3Y H24  H N N 377 
T3Y H22  H N N 378 
T3Y H22A H N N 379 
T3Y H2   H N N 380 
T3Y HO13 H N N 381 
T3Y H4   H N N 382 
T3Y H4A  H N N 383 
T3Y H6   H N N 384 
T3Y HO5  H N N 385 
T3Y H8   H N N 386 
T3Y HO16 H N N 387 
T3Y H10  H N N 388 
T3Y H10A H N N 389 
T3Y H12  H N N 390 
T3Y HO8  H N N 391 
T3Y H14  H N N 392 
T3Y HO15 H N N 393 
T3Y H16  H N N 394 
T3Y H16A H N N 395 
T3Y H18  H N N 396 
T3Y HO14 H N N 397 
T3Y H20  H N N 398 
T3Y HO10 H N N 399 
THR N    N N N 400 
THR CA   C N S 401 
THR C    C N N 402 
THR O    O N N 403 
THR CB   C N R 404 
THR OG1  O N N 405 
THR CG2  C N N 406 
THR OXT  O N N 407 
THR H    H N N 408 
THR H2   H N N 409 
THR HA   H N N 410 
THR HB   H N N 411 
THR HG1  H N N 412 
THR HG21 H N N 413 
THR HG22 H N N 414 
THR HG23 H N N 415 
THR HXT  H N N 416 
TRP N    N N N 417 
TRP CA   C N S 418 
TRP C    C N N 419 
TRP O    O N N 420 
TRP CB   C N N 421 
TRP CG   C Y N 422 
TRP CD1  C Y N 423 
TRP CD2  C Y N 424 
TRP NE1  N Y N 425 
TRP CE2  C Y N 426 
TRP CE3  C Y N 427 
TRP CZ2  C Y N 428 
TRP CZ3  C Y N 429 
TRP CH2  C Y N 430 
TRP OXT  O N N 431 
TRP H    H N N 432 
TRP H2   H N N 433 
TRP HA   H N N 434 
TRP HB2  H N N 435 
TRP HB3  H N N 436 
TRP HD1  H N N 437 
TRP HE1  H N N 438 
TRP HE3  H N N 439 
TRP HZ2  H N N 440 
TRP HZ3  H N N 441 
TRP HH2  H N N 442 
TRP HXT  H N N 443 
TYR N    N N N 444 
TYR CA   C N S 445 
TYR C    C N N 446 
TYR O    O N N 447 
TYR CB   C N N 448 
TYR CG   C Y N 449 
TYR CD1  C Y N 450 
TYR CD2  C Y N 451 
TYR CE1  C Y N 452 
TYR CE2  C Y N 453 
TYR CZ   C Y N 454 
TYR OH   O N N 455 
TYR OXT  O N N 456 
TYR H    H N N 457 
TYR H2   H N N 458 
TYR HA   H N N 459 
TYR HB2  H N N 460 
TYR HB3  H N N 461 
TYR HD1  H N N 462 
TYR HD2  H N N 463 
TYR HE1  H N N 464 
TYR HE2  H N N 465 
TYR HH   H N N 466 
TYR HXT  H N N 467 
VAL N    N N N 468 
VAL CA   C N S 469 
VAL C    C N N 470 
VAL O    O N N 471 
VAL CB   C N N 472 
VAL CG1  C N N 473 
VAL CG2  C N N 474 
VAL OXT  O N N 475 
VAL H    H N N 476 
VAL H2   H N N 477 
VAL HA   H N N 478 
VAL HB   H N N 479 
VAL HG11 H N N 480 
VAL HG12 H N N 481 
VAL HG13 H N N 482 
VAL HG21 H N N 483 
VAL HG22 H N N 484 
VAL HG23 H N N 485 
VAL HXT  H N N 486 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BDF C1  C2   sing N N 70  
BDF C1  O1   sing N N 71  
BDF C1  H11  sing N N 72  
BDF C1  H12  sing N N 73  
BDF C2  C3   sing N N 74  
BDF C2  O2   sing N N 75  
BDF C2  O6   sing N N 76  
BDF C3  C4   sing N N 77  
BDF C3  O3   sing N N 78  
BDF C3  H3   sing N N 79  
BDF C4  C5   sing N N 80  
BDF C4  O4   sing N N 81  
BDF C4  H4   sing N N 82  
BDF C5  C6   sing N N 83  
BDF C5  O5   sing N N 84  
BDF C5  H5   sing N N 85  
BDF C6  O6   sing N N 86  
BDF C6  H61  sing N N 87  
BDF C6  H62  sing N N 88  
BDF O1  HO1  sing N N 89  
BDF O2  HO2  sing N N 90  
BDF O3  HO3  sing N N 91  
BDF O4  HO4  sing N N 92  
BDF O5  HO5  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
GLN N   CA   sing N N 107 
GLN N   H    sing N N 108 
GLN N   H2   sing N N 109 
GLN CA  C    sing N N 110 
GLN CA  CB   sing N N 111 
GLN CA  HA   sing N N 112 
GLN C   O    doub N N 113 
GLN C   OXT  sing N N 114 
GLN CB  CG   sing N N 115 
GLN CB  HB2  sing N N 116 
GLN CB  HB3  sing N N 117 
GLN CG  CD   sing N N 118 
GLN CG  HG2  sing N N 119 
GLN CG  HG3  sing N N 120 
GLN CD  OE1  doub N N 121 
GLN CD  NE2  sing N N 122 
GLN NE2 HE21 sing N N 123 
GLN NE2 HE22 sing N N 124 
GLN OXT HXT  sing N N 125 
GLU N   CA   sing N N 126 
GLU N   H    sing N N 127 
GLU N   H2   sing N N 128 
GLU CA  C    sing N N 129 
GLU CA  CB   sing N N 130 
GLU CA  HA   sing N N 131 
GLU C   O    doub N N 132 
GLU C   OXT  sing N N 133 
GLU CB  CG   sing N N 134 
GLU CB  HB2  sing N N 135 
GLU CB  HB3  sing N N 136 
GLU CG  CD   sing N N 137 
GLU CG  HG2  sing N N 138 
GLU CG  HG3  sing N N 139 
GLU CD  OE1  doub N N 140 
GLU CD  OE2  sing N N 141 
GLU OE2 HE2  sing N N 142 
GLU OXT HXT  sing N N 143 
GLY N   CA   sing N N 144 
GLY N   H    sing N N 145 
GLY N   H2   sing N N 146 
GLY CA  C    sing N N 147 
GLY CA  HA2  sing N N 148 
GLY CA  HA3  sing N N 149 
GLY C   O    doub N N 150 
GLY C   OXT  sing N N 151 
GLY OXT HXT  sing N N 152 
HIS N   CA   sing N N 153 
HIS N   H    sing N N 154 
HIS N   H2   sing N N 155 
HIS CA  C    sing N N 156 
HIS CA  CB   sing N N 157 
HIS CA  HA   sing N N 158 
HIS C   O    doub N N 159 
HIS C   OXT  sing N N 160 
HIS CB  CG   sing N N 161 
HIS CB  HB2  sing N N 162 
HIS CB  HB3  sing N N 163 
HIS CG  ND1  sing Y N 164 
HIS CG  CD2  doub Y N 165 
HIS ND1 CE1  doub Y N 166 
HIS ND1 HD1  sing N N 167 
HIS CD2 NE2  sing Y N 168 
HIS CD2 HD2  sing N N 169 
HIS CE1 NE2  sing Y N 170 
HIS CE1 HE1  sing N N 171 
HIS NE2 HE2  sing N N 172 
HIS OXT HXT  sing N N 173 
HOH O   H1   sing N N 174 
HOH O   H2   sing N N 175 
ILE N   CA   sing N N 176 
ILE N   H    sing N N 177 
ILE N   H2   sing N N 178 
ILE CA  C    sing N N 179 
ILE CA  CB   sing N N 180 
ILE CA  HA   sing N N 181 
ILE C   O    doub N N 182 
ILE C   OXT  sing N N 183 
ILE CB  CG1  sing N N 184 
ILE CB  CG2  sing N N 185 
ILE CB  HB   sing N N 186 
ILE CG1 CD1  sing N N 187 
ILE CG1 HG12 sing N N 188 
ILE CG1 HG13 sing N N 189 
ILE CG2 HG21 sing N N 190 
ILE CG2 HG22 sing N N 191 
ILE CG2 HG23 sing N N 192 
ILE CD1 HD11 sing N N 193 
ILE CD1 HD12 sing N N 194 
ILE CD1 HD13 sing N N 195 
ILE OXT HXT  sing N N 196 
LEU N   CA   sing N N 197 
LEU N   H    sing N N 198 
LEU N   H2   sing N N 199 
LEU CA  C    sing N N 200 
LEU CA  CB   sing N N 201 
LEU CA  HA   sing N N 202 
LEU C   O    doub N N 203 
LEU C   OXT  sing N N 204 
LEU CB  CG   sing N N 205 
LEU CB  HB2  sing N N 206 
LEU CB  HB3  sing N N 207 
LEU CG  CD1  sing N N 208 
LEU CG  CD2  sing N N 209 
LEU CG  HG   sing N N 210 
LEU CD1 HD11 sing N N 211 
LEU CD1 HD12 sing N N 212 
LEU CD1 HD13 sing N N 213 
LEU CD2 HD21 sing N N 214 
LEU CD2 HD22 sing N N 215 
LEU CD2 HD23 sing N N 216 
LEU OXT HXT  sing N N 217 
LYS N   CA   sing N N 218 
LYS N   H    sing N N 219 
LYS N   H2   sing N N 220 
LYS CA  C    sing N N 221 
LYS CA  CB   sing N N 222 
LYS CA  HA   sing N N 223 
LYS C   O    doub N N 224 
LYS C   OXT  sing N N 225 
LYS CB  CG   sing N N 226 
LYS CB  HB2  sing N N 227 
LYS CB  HB3  sing N N 228 
LYS CG  CD   sing N N 229 
LYS CG  HG2  sing N N 230 
LYS CG  HG3  sing N N 231 
LYS CD  CE   sing N N 232 
LYS CD  HD2  sing N N 233 
LYS CD  HD3  sing N N 234 
LYS CE  NZ   sing N N 235 
LYS CE  HE2  sing N N 236 
LYS CE  HE3  sing N N 237 
LYS NZ  HZ1  sing N N 238 
LYS NZ  HZ2  sing N N 239 
LYS NZ  HZ3  sing N N 240 
LYS OXT HXT  sing N N 241 
MET N   CA   sing N N 242 
MET N   H    sing N N 243 
MET N   H2   sing N N 244 
MET CA  C    sing N N 245 
MET CA  CB   sing N N 246 
MET CA  HA   sing N N 247 
MET C   O    doub N N 248 
MET C   OXT  sing N N 249 
MET CB  CG   sing N N 250 
MET CB  HB2  sing N N 251 
MET CB  HB3  sing N N 252 
MET CG  SD   sing N N 253 
MET CG  HG2  sing N N 254 
MET CG  HG3  sing N N 255 
MET SD  CE   sing N N 256 
MET CE  HE1  sing N N 257 
MET CE  HE2  sing N N 258 
MET CE  HE3  sing N N 259 
MET OXT HXT  sing N N 260 
PHE N   CA   sing N N 261 
PHE N   H    sing N N 262 
PHE N   H2   sing N N 263 
PHE CA  C    sing N N 264 
PHE CA  CB   sing N N 265 
PHE CA  HA   sing N N 266 
PHE C   O    doub N N 267 
PHE C   OXT  sing N N 268 
PHE CB  CG   sing N N 269 
PHE CB  HB2  sing N N 270 
PHE CB  HB3  sing N N 271 
PHE CG  CD1  doub Y N 272 
PHE CG  CD2  sing Y N 273 
PHE CD1 CE1  sing Y N 274 
PHE CD1 HD1  sing N N 275 
PHE CD2 CE2  doub Y N 276 
PHE CD2 HD2  sing N N 277 
PHE CE1 CZ   doub Y N 278 
PHE CE1 HE1  sing N N 279 
PHE CE2 CZ   sing Y N 280 
PHE CE2 HE2  sing N N 281 
PHE CZ  HZ   sing N N 282 
PHE OXT HXT  sing N N 283 
PRO N   CA   sing N N 284 
PRO N   CD   sing N N 285 
PRO N   H    sing N N 286 
PRO CA  C    sing N N 287 
PRO CA  CB   sing N N 288 
PRO CA  HA   sing N N 289 
PRO C   O    doub N N 290 
PRO C   OXT  sing N N 291 
PRO CB  CG   sing N N 292 
PRO CB  HB2  sing N N 293 
PRO CB  HB3  sing N N 294 
PRO CG  CD   sing N N 295 
PRO CG  HG2  sing N N 296 
PRO CG  HG3  sing N N 297 
PRO CD  HD2  sing N N 298 
PRO CD  HD3  sing N N 299 
PRO OXT HXT  sing N N 300 
SER N   CA   sing N N 301 
SER N   H    sing N N 302 
SER N   H2   sing N N 303 
SER CA  C    sing N N 304 
SER CA  CB   sing N N 305 
SER CA  HA   sing N N 306 
SER C   O    doub N N 307 
SER C   OXT  sing N N 308 
SER CB  OG   sing N N 309 
SER CB  HB2  sing N N 310 
SER CB  HB3  sing N N 311 
SER OG  HG   sing N N 312 
SER OXT HXT  sing N N 313 
T3Y S1  O3   sing N N 314 
T3Y O3  HO3  sing N N 315 
T3Y O2  S1   doub N N 316 
T3Y S1  O1   doub N N 317 
T3Y S1  C1   sing N N 318 
T3Y C1  C2   doub Y N 319 
T3Y C1  C24  sing Y N 320 
T3Y C24 C23  doub Y N 321 
T3Y C24 H24  sing N N 322 
T3Y C23 C25  sing Y N 323 
T3Y C23 C22  sing N N 324 
T3Y C22 C21  sing N N 325 
T3Y C22 H22  sing N N 326 
T3Y C22 H22A sing N N 327 
T3Y C2  C3   sing Y N 328 
T3Y C2  H2   sing N N 329 
T3Y C3  C4   sing N N 330 
T3Y C3  C25  doub Y N 331 
T3Y C25 O13  sing N N 332 
T3Y O13 HO13 sing N N 333 
T3Y C4  C5   sing N N 334 
T3Y C4  H4   sing N N 335 
T3Y C4  H4A  sing N N 336 
T3Y C5  C6   doub Y N 337 
T3Y C5  C28  sing Y N 338 
T3Y C6  C7   sing Y N 339 
T3Y C6  H6   sing N N 340 
T3Y C7  S2   sing N N 341 
T3Y C7  C8   doub Y N 342 
T3Y O6  S2   doub N N 343 
T3Y S2  O4   doub N N 344 
T3Y S2  O5   sing N N 345 
T3Y O5  HO5  sing N N 346 
T3Y C9  C8   sing Y N 347 
T3Y C8  H8   sing N N 348 
T3Y O16 C28  sing N N 349 
T3Y C28 C9   doub Y N 350 
T3Y O16 HO16 sing N N 351 
T3Y C9  C10  sing N N 352 
T3Y C10 C11  sing N N 353 
T3Y C10 H10  sing N N 354 
T3Y C10 H10A sing N N 355 
T3Y C27 C11  doub Y N 356 
T3Y C11 C12  sing Y N 357 
T3Y C12 C13  doub Y N 358 
T3Y C12 H12  sing N N 359 
T3Y C14 C13  sing Y N 360 
T3Y C13 S3   sing N N 361 
T3Y O9  S3   doub N N 362 
T3Y S3  O7   doub N N 363 
T3Y S3  O8   sing N N 364 
T3Y O8  HO8  sing N N 365 
T3Y C15 C14  doub Y N 366 
T3Y C14 H14  sing N N 367 
T3Y O15 C27  sing N N 368 
T3Y C27 C15  sing Y N 369 
T3Y O15 HO15 sing N N 370 
T3Y C16 C15  sing N N 371 
T3Y C17 C16  sing N N 372 
T3Y C16 H16  sing N N 373 
T3Y C16 H16A sing N N 374 
T3Y C26 C17  doub Y N 375 
T3Y C17 C18  sing Y N 376 
T3Y C19 C18  doub Y N 377 
T3Y C18 H18  sing N N 378 
T3Y C21 C26  sing Y N 379 
T3Y O14 C26  sing N N 380 
T3Y O14 HO14 sing N N 381 
T3Y C21 C20  doub Y N 382 
T3Y C20 C19  sing Y N 383 
T3Y C20 H20  sing N N 384 
T3Y C19 S4   sing N N 385 
T3Y O11 S4   doub N N 386 
T3Y S4  O12  doub N N 387 
T3Y S4  O10  sing N N 388 
T3Y O10 HO10 sing N N 389 
THR N   CA   sing N N 390 
THR N   H    sing N N 391 
THR N   H2   sing N N 392 
THR CA  C    sing N N 393 
THR CA  CB   sing N N 394 
THR CA  HA   sing N N 395 
THR C   O    doub N N 396 
THR C   OXT  sing N N 397 
THR CB  OG1  sing N N 398 
THR CB  CG2  sing N N 399 
THR CB  HB   sing N N 400 
THR OG1 HG1  sing N N 401 
THR CG2 HG21 sing N N 402 
THR CG2 HG22 sing N N 403 
THR CG2 HG23 sing N N 404 
THR OXT HXT  sing N N 405 
TRP N   CA   sing N N 406 
TRP N   H    sing N N 407 
TRP N   H2   sing N N 408 
TRP CA  C    sing N N 409 
TRP CA  CB   sing N N 410 
TRP CA  HA   sing N N 411 
TRP C   O    doub N N 412 
TRP C   OXT  sing N N 413 
TRP CB  CG   sing N N 414 
TRP CB  HB2  sing N N 415 
TRP CB  HB3  sing N N 416 
TRP CG  CD1  doub Y N 417 
TRP CG  CD2  sing Y N 418 
TRP CD1 NE1  sing Y N 419 
TRP CD1 HD1  sing N N 420 
TRP CD2 CE2  doub Y N 421 
TRP CD2 CE3  sing Y N 422 
TRP NE1 CE2  sing Y N 423 
TRP NE1 HE1  sing N N 424 
TRP CE2 CZ2  sing Y N 425 
TRP CE3 CZ3  doub Y N 426 
TRP CE3 HE3  sing N N 427 
TRP CZ2 CH2  doub Y N 428 
TRP CZ2 HZ2  sing N N 429 
TRP CZ3 CH2  sing Y N 430 
TRP CZ3 HZ3  sing N N 431 
TRP CH2 HH2  sing N N 432 
TRP OXT HXT  sing N N 433 
TYR N   CA   sing N N 434 
TYR N   H    sing N N 435 
TYR N   H2   sing N N 436 
TYR CA  C    sing N N 437 
TYR CA  CB   sing N N 438 
TYR CA  HA   sing N N 439 
TYR C   O    doub N N 440 
TYR C   OXT  sing N N 441 
TYR CB  CG   sing N N 442 
TYR CB  HB2  sing N N 443 
TYR CB  HB3  sing N N 444 
TYR CG  CD1  doub Y N 445 
TYR CG  CD2  sing Y N 446 
TYR CD1 CE1  sing Y N 447 
TYR CD1 HD1  sing N N 448 
TYR CD2 CE2  doub Y N 449 
TYR CD2 HD2  sing N N 450 
TYR CE1 CZ   doub Y N 451 
TYR CE1 HE1  sing N N 452 
TYR CE2 CZ   sing Y N 453 
TYR CE2 HE2  sing N N 454 
TYR CZ  OH   sing N N 455 
TYR OH  HH   sing N N 456 
TYR OXT HXT  sing N N 457 
VAL N   CA   sing N N 458 
VAL N   H    sing N N 459 
VAL N   H2   sing N N 460 
VAL CA  C    sing N N 461 
VAL CA  CB   sing N N 462 
VAL CA  HA   sing N N 463 
VAL C   O    doub N N 464 
VAL C   OXT  sing N N 465 
VAL CB  CG1  sing N N 466 
VAL CB  CG2  sing N N 467 
VAL CB  HB   sing N N 468 
VAL CG1 HG11 sing N N 469 
VAL CG1 HG12 sing N N 470 
VAL CG1 HG13 sing N N 471 
VAL CG2 HG21 sing N N 472 
VAL CG2 HG22 sing N N 473 
VAL CG2 HG23 sing N N 474 
VAL OXT HXT  sing N N 475 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Irish Research Council'     Ireland GOIPG/2021/333 1 
'Science Foundation Ireland' Ireland 12/RC/2275_P2  2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   2BT9 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9GR4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.022703 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000156 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.013597 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.013177 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . MET A  1 1  ? -5.66630  -23.36657 -25.19367 1.000 22.56245 ? -1  MET B N   1 
ATOM   2    C CA  . MET A  1 1  ? -6.84377  -22.52831 -24.97490 1.000 26.12724 ? -1  MET B CA  1 
ATOM   3    C C   . MET A  1 1  ? -6.61869  -21.11628 -25.51186 1.000 35.65739 ? -1  MET B C   1 
ATOM   4    O O   . MET A  1 1  ? -5.48268  -20.64602 -25.58405 1.000 31.85516 ? -1  MET B O   1 
ATOM   5    C CB  . MET A  1 1  ? -7.20166  -22.46932 -23.48577 1.000 25.81864 ? -1  MET B CB  1 
ATOM   6    C CG  . MET A  1 1  ? -7.83890  -23.73918 -22.93306 1.000 24.85532 ? -1  MET B CG  1 
ATOM   7    S SD  . MET A  1 1  ? -8.16388  -23.64165 -21.15813 1.000 27.06966 ? -1  MET B SD  1 
ATOM   8    C CE  . MET A  1 1  ? -6.50280  -23.49421 -20.50081 1.000 27.37348 ? -1  MET B CE  1 
ATOM   9    N N   . LYS A  1 2  ? -7.70841  -20.44971 -25.89434 1.000 43.47697 ? 0   LYS B N   1 
ATOM   10   C CA  . LYS A  1 2  ? -7.66672  -19.07443 -26.37309 1.000 35.69011 ? 0   LYS B CA  1 
ATOM   11   C C   . LYS A  1 2  ? -8.87131  -18.32214 -25.82084 1.000 40.09351 ? 0   LYS B C   1 
ATOM   12   O O   . LYS A  1 2  ? -9.81422  -18.91780 -25.29174 1.000 32.25925 ? 0   LYS B O   1 
ATOM   13   C CB  . LYS A  1 2  ? -7.64984  -19.00176 -27.90780 1.000 34.66633 ? 0   LYS B CB  1 
ATOM   14   C CG  . LYS A  1 2  ? -6.45025  -19.67103 -28.56799 1.000 39.91385 ? 0   LYS B CG  1 
ATOM   15   C CD  . LYS A  1 2  ? -6.42948  -19.40365 -30.06626 1.000 53.06360 ? 0   LYS B CD  1 
ATOM   16   C CE  . LYS A  1 2  ? -5.27325  -20.11682 -30.75368 1.000 49.71764 ? 0   LYS B CE  1 
ATOM   17   N NZ  . LYS A  1 2  ? -5.48861  -21.58906 -30.84345 1.000 49.06187 ? 0   LYS B NZ  1 
ATOM   18   N N   . ALA A  1 3  ? -8.83252  -16.99585 -25.94607 1.000 28.70369 ? 1   ALA B N   1 
ATOM   19   C CA  . ALA A  1 3  ? -9.95107  -16.17251 -25.50647 1.000 25.54230 ? 1   ALA B CA  1 
ATOM   20   C C   . ALA A  1 3  ? -11.19035 -16.47133 -26.34432 1.000 27.21515 ? 1   ALA B C   1 
ATOM   21   O O   . ALA A  1 3  ? -11.10003 -16.84814 -27.51570 1.000 32.25010 ? 1   ALA B O   1 
ATOM   22   C CB  . ALA A  1 3  ? -9.59149  -14.69192 -25.62696 1.000 27.99895 ? 1   ALA B CB  1 
ATOM   23   N N   . SER A  1 4  ? -12.36521 -16.29926 -25.73246 1.000 21.35848 ? 2   SER B N   1 
ATOM   24   C CA  . SER A  1 4  ? -13.61722 -16.62623 -26.40100 1.000 25.83226 ? 2   SER B CA  1 
ATOM   25   C C   . SER A  1 4  ? -14.43233 -15.41913 -26.84635 1.000 36.17448 ? 2   SER B C   1 
ATOM   26   O O   . SER A  1 4  ? -15.28487 -15.57126 -27.72650 1.000 36.46193 ? 2   SER B O   1 
ATOM   27   C CB  . SER A  1 4  ? -14.48970 -17.53881 -25.52468 1.000 39.12678 ? 2   SER B CB  1 
ATOM   28   O OG  . SER A  1 4  ? -14.84428 -16.90457 -24.31068 1.000 46.05442 ? 2   SER B OG  1 
ATOM   29   N N   . VAL A  1 5  ? -14.21140 -14.23703 -26.26792 1.000 18.18440 ? 3   VAL B N   1 
ATOM   30   C CA  . VAL A  1 5  ? -14.85902 -13.02489 -26.75504 1.000 16.23158 ? 3   VAL B CA  1 
ATOM   31   C C   . VAL A  1 5  ? -13.79576 -11.99959 -27.12808 1.000 14.75914 ? 3   VAL B C   1 
ATOM   32   O O   . VAL A  1 5  ? -12.64281 -12.06430 -26.69038 1.000 17.87761 ? 3   VAL B O   1 
ATOM   33   C CB  . VAL A  1 5  ? -15.90119 -12.42615 -25.78582 1.000 19.14639 ? 3   VAL B CB  1 
ATOM   34   C CG1 . VAL A  1 5  ? -16.79973 -13.51569 -25.22187 1.000 24.76919 ? 3   VAL B CG1 1 
ATOM   35   C CG2 . VAL A  1 5  ? -15.22505 -11.64640 -24.68176 1.000 25.72882 ? 3   VAL B CG2 1 
ATOM   36   N N   . GLN A  1 6  ? -14.20031 -11.05079 -27.97031 1.000 11.52723 ? 4   GLN B N   1 
ATOM   37   C CA  . GLN A  1 6  ? -13.30215 -10.02496 -28.47930 1.000 10.40178 ? 4   GLN B CA  1 
ATOM   38   C C   . GLN A  1 6  ? -14.08828 -8.72619  -28.58106 1.000 10.26434 ? 4   GLN B C   1 
ATOM   39   O O   . GLN A  1 6  ? -15.22091 -8.73383  -29.06749 1.000 11.02651 ? 4   GLN B O   1 
ATOM   40   C CB  . GLN A  1 6  ? -12.75168 -10.44625 -29.84938 1.000 11.74452 ? 4   GLN B CB  1 
ATOM   41   C CG  . GLN A  1 6  ? -11.73985 -9.49850  -30.45383 1.000 12.45392 ? 4   GLN B CG  1 
ATOM   42   C CD  . GLN A  1 6  ? -12.35964 -8.56290  -31.46066 1.000 10.57776 ? 4   GLN B CD  1 
ATOM   43   O OE1 . GLN A  1 6  ? -13.37174 -8.88596  -32.08220 1.000 11.17967 ? 4   GLN B OE1 1 
ATOM   44   N NE2 . GLN A  1 6  ? -11.74682 -7.39872  -31.64031 1.000 15.01614 ? 4   GLN B NE2 1 
ATOM   45   N N   . THR A  1 7  ? -13.50936 -7.62048  -28.11063 1.000 9.31511  ? 5   THR B N   1 
ATOM   46   C CA  . THR A  1 7  ? -14.21999 -6.35292  -28.08418 1.000 7.88903  ? 5   THR B CA  1 
ATOM   47   C C   . THR A  1 7  ? -13.46271 -5.27794  -28.85198 1.000 8.29034  ? 5   THR B C   1 
ATOM   48   O O   . THR A  1 7  ? -12.26843 -5.39743  -29.14137 1.000 9.00927  ? 5   THR B O   1 
ATOM   49   C CB  . THR A  1 7  ? -14.46260 -5.85305  -26.64748 1.000 8.13397  ? 5   THR B CB  1 
ATOM   50   O OG1 . THR A  1 7  ? -13.21064 -5.50846  -26.04172 1.000 9.64517  ? 5   THR B OG1 1 
ATOM   51   C CG2 . THR A  1 7  ? -15.18142 -6.90826  -25.81302 1.000 9.44007  ? 5   THR B CG2 1 
ATOM   52   N N   . ALA A  1 8  ? -14.19677 -4.21526  -29.16789 1.000 8.01790  ? 6   ALA B N   1 
ATOM   53   C CA  . ALA A  1 8  ? -13.65902 -2.99684  -29.75471 1.000 7.10777  ? 6   ALA B CA  1 
ATOM   54   C C   . ALA A  1 8  ? -14.45558 -1.83895  -29.18108 1.000 7.85553  ? 6   ALA B C   1 
ATOM   55   O O   . ALA A  1 8  ? -15.61859 -2.00982  -28.80448 1.000 9.47571  ? 6   ALA B O   1 
ATOM   56   C CB  . ALA A  1 8  ? -13.77343 -3.00646  -31.28636 1.000 9.37299  ? 6   ALA B CB  1 
ATOM   57   N N   . ALA A  1 9  ? -13.83436 -0.66641  -29.08323 1.000 7.71534  ? 7   ALA B N   1 
ATOM   58   C CA  . ALA A  1 9  ? -14.48266 0.46221   -28.43286 1.000 8.26147  ? 7   ALA B CA  1 
ATOM   59   C C   . ALA A  1 9  ? -14.11860 1.76194   -29.13389 1.000 7.17108  ? 7   ALA B C   1 
ATOM   60   O O   . ALA A  1 9  ? -13.01841 1.91804   -29.67429 1.000 8.08859  ? 7   ALA B O   1 
ATOM   61   C CB  . ALA A  1 9  ? -14.09438 0.55376   -26.95033 1.000 10.03876 ? 7   ALA B CB  1 
ATOM   62   N N   . THR A  1 10 ? -15.05461 2.70519   -29.10565 1.000 8.22086  ? 8   THR B N   1 
ATOM   63   C CA  . THR A  1 10 ? -14.80563 4.05935   -29.57000 1.000 7.88672  ? 8   THR B CA  1 
ATOM   64   C C   . THR A  1 10 ? -15.55168 5.02317   -28.65593 1.000 8.22026  ? 8   THR B C   1 
ATOM   65   O O   . THR A  1 10 ? -16.42802 4.62035   -27.88264 1.000 9.18020  ? 8   THR B O   1 
ATOM   66   C CB  . THR A  1 10 ? -15.21661 4.23778   -31.04447 1.000 8.55272  ? 8   THR B CB  1 
ATOM   67   O OG1 . THR A  1 10 ? -14.65986 5.44952   -31.55936 1.000 9.71447  ? 8   THR B OG1 1 
ATOM   68   C CG2 . THR A  1 10 ? -16.73512 4.28168   -31.22202 1.000 9.85797  ? 8   THR B CG2 1 
ATOM   69   N N   . SER A  1 11 ? -15.18767 6.30161   -28.73248 1.000 8.16461  ? 9   SER B N   1 
ATOM   70   C CA  . SER A  1 11 ? -15.81665 7.30520   -27.88571 1.000 9.06120  ? 9   SER B CA  1 
ATOM   71   C C   . SER A  1 11 ? -15.67671 8.66606   -28.54400 1.000 9.05954  ? 9   SER B C   1 
ATOM   72   O O   . SER A  1 11 ? -14.80974 8.87024   -29.39638 1.000 9.81039  ? 9   SER B O   1 
ATOM   73   C CB  . SER A  1 11 ? -15.18994 7.33536   -26.49030 1.000 10.53575 ? 9   SER B CB  1 
ATOM   74   O OG  . SER A  1 11 ? -13.80966 7.64724   -26.56253 1.000 9.87045  ? 9   SER B OG  1 
ATOM   75   N N   . TRP A  1 12 ? -16.53606 9.60075   -28.13813 1.000 9.93018  ? 10  TRP B N   1 
ATOM   76   C CA  . TRP A  1 12 ? -16.47360 10.95125  -28.68286 1.000 11.49453 ? 10  TRP B CA  1 
ATOM   77   C C   . TRP A  1 12 ? -17.03931 11.95943  -27.69318 1.000 10.66019 ? 10  TRP B C   1 
ATOM   78   O O   . TRP A  1 12 ? -17.85322 11.62893  -26.82588 1.000 11.76763 ? 10  TRP B O   1 
ATOM   79   C CB  . TRP A  1 12 ? -17.18468 11.06905  -30.03876 1.000 12.69880 ? 10  TRP B CB  1 
ATOM   80   C CG  . TRP A  1 12 ? -18.67239 10.83651  -30.00799 1.000 10.85823 ? 10  TRP B CG  1 
ATOM   81   C CD1 . TRP A  1 12 ? -19.64774 11.78090  -29.84717 1.000 13.56340 ? 10  TRP B CD1 1 
ATOM   82   C CD2 . TRP A  1 12 ? -19.35173 9.58224   -30.16714 1.000 11.63124 ? 10  TRP B CD2 1 
ATOM   83   N NE1 . TRP A  1 12 ? -20.88786 11.19020  -29.89037 1.000 13.10434 ? 10  TRP B NE1 1 
ATOM   84   C CE2 . TRP A  1 12 ? -20.73597 9.84237   -30.08777 1.000 10.81526 ? 10  TRP B CE2 1 
ATOM   85   C CE3 . TRP A  1 12 ? -18.92455 8.26415   -30.36970 1.000 10.84627 ? 10  TRP B CE3 1 
ATOM   86   C CZ2 . TRP A  1 12 ? -21.69645 8.83314   -30.19884 1.000 12.11491 ? 10  TRP B CZ2 1 
ATOM   87   C CZ3 . TRP A  1 12 ? -19.87704 7.26488   -30.47895 1.000 12.00578 ? 10  TRP B CZ3 1 
ATOM   88   C CH2 . TRP A  1 12 ? -21.24753 7.55282   -30.39283 1.000 13.11340 ? 10  TRP B CH2 1 
ATOM   89   N N   . GLY A  1 13 ? -16.60103 13.20557  -27.85202 1.000 11.93814 ? 11  GLY B N   1 
ATOM   90   C CA  . GLY A  1 13 ? -17.07235 14.28447  -27.01394 1.000 14.31786 ? 11  GLY B CA  1 
ATOM   91   C C   . GLY A  1 13 ? -16.48521 14.21794  -25.61516 1.000 15.81918 ? 11  GLY B C   1 
ATOM   92   O O   . GLY A  1 13 ? -15.55340 13.46632  -25.32491 1.000 17.84559 ? 11  GLY B O   1 
ATOM   93   N N   . THR A  1 14 ? -17.06268 15.03686  -24.73203 1.000 17.32987 ? 12  THR B N   1 
ATOM   94   C CA  . THR A  1 14 ? -16.59008 15.14498  -23.36028 1.000 17.21842 ? 12  THR B CA  1 
ATOM   95   C C   . THR A  1 14 ? -17.54734 14.56468  -22.32824 1.000 17.67285 ? 12  THR B C   1 
ATOM   96   O O   . THR A  1 14 ? -17.20180 14.53427  -21.14141 1.000 19.98996 ? 12  THR B O   1 
ATOM   97   C CB  . THR A  1 14 ? -16.28686 16.60944  -23.00905 1.000 24.61051 ? 12  THR B CB  1 
ATOM   98   O OG1 . THR A  1 14 ? -17.48447 17.38658  -23.13478 1.000 24.50203 ? 12  THR B OG1 1 
ATOM   99   C CG2 . THR A  1 14 ? -15.21509 17.16917  -23.93818 1.000 26.04532 ? 12  THR B CG2 1 
ATOM   100  N N   . VAL A  1 15 ? -18.73538 14.11200  -22.73636 1.000 16.38694 ? 13  VAL B N   1 
ATOM   101  C CA  . VAL A  1 15 ? -19.63439 13.44586  -21.78987 1.000 16.13190 ? 13  VAL B CA  1 
ATOM   102  C C   . VAL A  1 15 ? -18.99772 12.21087  -21.16333 1.000 16.05859 ? 13  VAL B C   1 
ATOM   103  O O   . VAL A  1 15 ? -19.02425 12.08755  -19.92673 1.000 15.70817 ? 13  VAL B O   1 
ATOM   104  C CB  . VAL A  1 15 ? -21.00968 13.19698  -22.43390 1.000 16.73665 ? 13  VAL B CB  1 
ATOM   105  C CG1 . VAL A  1 15 ? -21.91740 12.43880  -21.47225 1.000 18.22069 ? 13  VAL B CG1 1 
ATOM   106  C CG2 . VAL A  1 15 ? -21.64179 14.51808  -22.85814 1.000 17.95102 ? 13  VAL B CG2 1 
ATOM   107  N N   . PRO A  1 16 ? -18.42752 11.26346  -21.92453 1.000 12.93177 ? 14  PRO B N   1 
ATOM   108  C CA  . PRO A  1 16 ? -18.43342 11.12990  -23.38188 1.000 12.15848 ? 14  PRO B CA  1 
ATOM   109  C C   . PRO A  1 16 ? -19.57422 10.21428  -23.78330 1.000 10.55999 ? 14  PRO B C   1 
ATOM   110  O O   . PRO A  1 16 ? -20.29530 9.67229   -22.93929 1.000 11.40597 ? 14  PRO B O   1 
ATOM   111  C CB  . PRO A  1 16 ? -17.11414 10.40238  -23.63405 1.000 11.78100 ? 14  PRO B CB  1 
ATOM   112  C CG  . PRO A  1 16 ? -17.08028 9.42064   -22.49618 1.000 13.52021 ? 14  PRO B CG  1 
ATOM   113  C CD  . PRO A  1 16 ? -17.62038 10.19651  -21.30501 1.000 14.68179 ? 14  PRO B CD  1 
ATOM   114  N N   . SER A  1 17 ? -19.75324 10.01976  -25.08191 1.000 10.70032 ? 15  SER B N   1 
ATOM   115  C CA  . SER A  1 17 ? -20.44218 8.84398   -25.58065 1.000 10.03137 ? 15  SER B CA  1 
ATOM   116  C C   . SER A  1 17 ? -19.40104 7.76013   -25.82072 1.000 9.20909  ? 15  SER B C   1 
ATOM   117  O O   . SER A  1 17 ? -18.31578 8.03234   -26.34378 1.000 9.43034  ? 15  SER B O   1 
ATOM   118  C CB  . SER A  1 17 ? -21.16339 9.15430   -26.88906 1.000 10.49400 ? 15  SER B CB  1 
ATOM   119  O OG  . SER A  1 17 ? -22.33993 9.92202   -26.67365 1.000 11.86074 ? 15  SER B OG  1 
ATOM   120  N N   . ILE A  1 18 ? -19.72278 6.53713   -25.40803 1.000 8.24471  ? 16  ILE B N   1 
ATOM   121  C CA  . ILE A  1 18 ? -18.87340 5.37265   -25.62368 1.000 8.50828  ? 16  ILE B CA  1 
ATOM   122  C C   . ILE A  1 18 ? -19.71577 4.31192   -26.30816 1.000 8.22514  ? 16  ILE B C   1 
ATOM   123  O O   . ILE A  1 18 ? -20.89432 4.13438   -25.97063 1.000 8.10085  ? 16  ILE B O   1 
ATOM   124  C CB  . ILE A  1 18 ? -18.31843 4.80377   -24.30064 1.000 8.30556  ? 16  ILE B CB  1 
ATOM   125  C CG1 . ILE A  1 18 ? -17.73319 5.90801   -23.41549 1.000 10.37830 ? 16  ILE B CG1 1 
ATOM   126  C CG2 . ILE A  1 18 ? -17.29441 3.69267   -24.57273 1.000 8.72993  ? 16  ILE B CG2 1 
ATOM   127  C CD1 . ILE A  1 18 ? -17.38223 5.43306   -22.01671 1.000 11.48967 ? 16  ILE B CD1 1 
ATOM   128  N N   . ARG A  1 19 ? -19.11449 3.59883   -27.25803 1.000 8.34185  ? 17  ARG B N   1 
ATOM   129  C CA  . ARG A  1 19 ? -19.73463 2.42985   -27.86392 1.000 8.14971  ? 17  ARG B CA  1 
ATOM   130  C C   . ARG A  1 19 ? -18.74314 1.28205   -27.77435 1.000 7.85018  ? 17  ARG B C   1 
ATOM   131  O O   . ARG A  1 19 ? -17.58294 1.43074   -28.18341 1.000 8.67618  ? 17  ARG B O   1 
ATOM   132  C CB  . ARG A  1 19 ? -20.12190 2.68942   -29.32806 1.000 8.77017  ? 17  ARG B CB  1 
ATOM   133  C CG  . ARG A  1 19 ? -21.10451 3.84252   -29.51585 1.000 8.95681  ? 17  ARG B CG  1 
ATOM   134  C CD  . ARG A  1 19 ? -22.47232 3.50625   -28.91545 1.000 8.93249  ? 17  ARG B CD  1 
ATOM   135  N NE  . ARG A  1 19 ? -23.46121 4.55673   -29.13595 1.000 9.53064  ? 17  ARG B NE  1 
ATOM   136  C CZ  . ARG A  1 19 ? -23.66719 5.57842   -28.31415 1.000 9.16224  ? 17  ARG B CZ  1 
ATOM   137  N NH1 . ARG A  1 19 ? -22.98135 5.71408   -27.19029 1.000 9.41439  ? 17  ARG B NH1 1 
ATOM   138  N NH2 . ARG A  1 19 ? -24.59439 6.48396   -28.62372 1.000 11.51692 ? 17  ARG B NH2 1 
ATOM   139  N N   . VAL A  1 20 ? -19.19690 0.14720   -27.24942 1.000 7.48847  ? 18  VAL B N   1 
ATOM   140  C CA  . VAL A  1 20 ? -18.37525 -1.04504  -27.07300 1.000 8.18078  ? 18  VAL B CA  1 
ATOM   141  C C   . VAL A  1 20 ? -19.03494 -2.17907  -27.84244 1.000 8.36940  ? 18  VAL B C   1 
ATOM   142  O O   . VAL A  1 20 ? -20.19781 -2.51815  -27.58230 1.000 8.33066  ? 18  VAL B O   1 
ATOM   143  C CB  . VAL A  1 20 ? -18.21628 -1.42791  -25.59047 1.000 8.83525  ? 18  VAL B CB  1 
ATOM   144  C CG1 . VAL A  1 20 ? -17.37787 -2.69482  -25.45597 1.000 9.59463  ? 18  VAL B CG1 1 
ATOM   145  C CG2 . VAL A  1 20 ? -17.60466 -0.28083  -24.78218 1.000 10.12049 ? 18  VAL B CG2 1 
ATOM   146  N N   . TYR A  1 21 ? -18.29750 -2.76992  -28.77856 1.000 8.15737  ? 19  TYR B N   1 
ATOM   147  C CA  . TYR A  1 21 ? -18.76980 -3.86061  -29.62293 1.000 8.68420  ? 19  TYR B CA  1 
ATOM   148  C C   . TYR A  1 21 ? -18.12724 -5.15022  -29.14557 1.000 8.40105  ? 19  TYR B C   1 
ATOM   149  O O   . TYR A  1 21 ? -16.92299 -5.17930  -28.88065 1.000 9.27272  ? 19  TYR B O   1 
ATOM   150  C CB  . TYR A  1 21 ? -18.38977 -3.58396  -31.08885 1.000 8.78964  ? 19  TYR B CB  1 
ATOM   151  C CG  . TYR A  1 21 ? -18.98568 -2.27338  -31.52583 1.000 8.85270  ? 19  TYR B CG  1 
ATOM   152  C CD1 . TYR A  1 21 ? -18.32664 -1.06983  -31.30250 1.000 8.49131  ? 19  TYR B CD1 1 
ATOM   153  C CD2 . TYR A  1 21 ? -20.24869 -2.22637  -32.08625 1.000 8.22283  ? 19  TYR B CD2 1 
ATOM   154  C CE1 . TYR A  1 21 ? -18.90230 0.13479   -31.63585 1.000 8.38218  ? 19  TYR B CE1 1 
ATOM   155  C CE2 . TYR A  1 21 ? -20.83054 -1.02687  -32.43045 1.000 9.25433  ? 19  TYR B CE2 1 
ATOM   156  C CZ  . TYR A  1 21 ? -20.15402 0.14954   -32.20157 1.000 8.58203  ? 19  TYR B CZ  1 
ATOM   157  O OH  . TYR A  1 21 ? -20.73620 1.35467   -32.51499 1.000 9.01848  ? 19  TYR B OH  1 
ATOM   158  N N   . THR A  1 22 ? -18.92724 -6.20790  -29.02100 1.000 8.98154  ? 20  THR B N   1 
ATOM   159  C CA  . THR A  1 22 ? -18.44502 -7.50657  -28.56894 1.000 8.59371  ? 20  THR B CA  1 
ATOM   160  C C   . THR A  1 22 ? -18.80216 -8.56031  -29.60323 1.000 9.19972  ? 20  THR B C   1 
ATOM   161  O O   . THR A  1 22 ? -19.97796 -8.72255  -29.95031 1.000 10.68198 ? 20  THR B O   1 
ATOM   162  C CB  . THR A  1 22 ? -19.06213 -7.88817  -27.22354 1.000 10.26021 ? 20  THR B CB  1 
ATOM   163  O OG1 . THR A  1 22 ? -18.71156 -6.90415  -26.24941 1.000 10.71857 ? 20  THR B OG1 1 
ATOM   164  C CG2 . THR A  1 22 ? -18.53831 -9.26010  -26.76641 1.000 11.88929 ? 20  THR B CG2 1 
ATOM   165  N N   . ALA A  1 23 ? -17.78855 -9.27475  -30.08271 1.000 10.33772 ? 21  ALA B N   1 
ATOM   166  C CA  . ALA A  1 23 ? -17.97821 -10.43097 -30.94781 1.000 11.27461 ? 21  ALA B CA  1 
ATOM   167  C C   . ALA A  1 23 ? -17.97155 -11.68663 -30.08285 1.000 12.69561 ? 21  ALA B C   1 
ATOM   168  O O   . ALA A  1 23 ? -16.99846 -11.95315 -29.36657 1.000 13.47312 ? 21  ALA B O   1 
ATOM   169  C CB  . ALA A  1 23 ? -16.87837 -10.50781 -32.00716 1.000 12.30258 ? 21  ALA B CB  1 
ATOM   170  N N   . ASN A  1 24 ? -19.05682 -12.45009 -30.15475 1.000 13.00714 ? 22  ASN B N   1 
ATOM   171  C CA  . ASN A  1 24 ? -19.23361 -13.63743 -29.33159 1.000 16.74026 ? 22  ASN B CA  1 
ATOM   172  C C   . ASN A  1 24 ? -20.13607 -14.59597 -30.09058 1.000 16.87457 ? 22  ASN B C   1 
ATOM   173  O O   . ASN A  1 24 ? -21.23248 -14.21302 -30.50784 1.000 18.41853 ? 22  ASN B O   1 
ATOM   174  C CB  . ASN A  1 24 ? -19.87486 -13.25699 -27.99083 1.000 18.39305 ? 22  ASN B CB  1 
ATOM   175  C CG  . ASN A  1 24 ? -20.04644 -14.44368 -27.06042 1.000 28.15430 ? 22  ASN B CG  1 
ATOM   176  O OD1 . ASN A  1 24 ? -19.33056 -15.43937 -27.16210 1.000 27.27384 ? 22  ASN B OD1 1 
ATOM   177  N ND2 . ASN A  1 24 ? -20.99883 -14.33727 -26.14047 1.000 27.03810 ? 22  ASN B ND2 1 
ATOM   178  N N   . ASN A  1 25 ? -19.66677 -15.82915 -30.27782 1.000 19.68111 ? 23  ASN B N   1 
ATOM   179  C CA  . ASN A  1 25 ? -20.44310 -16.86589 -30.96287 1.000 23.02498 ? 23  ASN B CA  1 
ATOM   180  C C   . ASN A  1 25 ? -20.90814 -16.41124 -32.34502 1.000 22.66822 ? 23  ASN B C   1 
ATOM   181  O O   . ASN A  1 25 ? -22.04459 -16.65733 -32.75324 1.000 22.05784 ? 23  ASN B O   1 
ATOM   182  C CB  . ASN A  1 25 ? -21.62191 -17.34973 -30.11301 1.000 25.04536 ? 23  ASN B CB  1 
ATOM   183  C CG  . ASN A  1 25 ? -21.18046 -18.01429 -28.82578 1.000 34.56349 ? 23  ASN B CG  1 
ATOM   184  O OD1 . ASN A  1 25 ? -20.16426 -18.70836 -28.78909 1.000 31.66815 ? 23  ASN B OD1 1 
ATOM   185  N ND2 . ASN A  1 25 ? -21.94421 -17.80285 -27.75819 1.000 35.50134 ? 23  ASN B ND2 1 
ATOM   186  N N   . GLY A  1 26 ? -20.02646 -15.72297 -33.06703 1.000 19.66409 ? 24  GLY B N   1 
ATOM   187  C CA  . GLY A  1 26 ? -20.33304 -15.30127 -34.41796 1.000 21.55221 ? 24  GLY B CA  1 
ATOM   188  C C   . GLY A  1 26 ? -21.25544 -14.11061 -34.54553 1.000 18.79716 ? 24  GLY B C   1 
ATOM   189  O O   . GLY A  1 26 ? -21.66578 -13.78822 -35.66630 1.000 18.20558 ? 24  GLY B O   1 
ATOM   190  N N   . LYS A  1 27 ? -21.59024 -13.44047 -33.44459 1.000 15.78839 ? 25  LYS B N   1 
ATOM   191  C CA  . LYS A  1 27 ? -22.47435 -12.28385 -33.47080 1.000 16.54191 ? 25  LYS B CA  1 
ATOM   192  C C   . LYS A  1 27 ? -21.79164 -11.11365 -32.77904 1.000 12.41644 ? 25  LYS B C   1 
ATOM   193  O O   . LYS A  1 27 ? -21.13500 -11.29382 -31.74850 1.000 13.56815 ? 25  LYS B O   1 
ATOM   194  C CB  . LYS A  1 27 ? -23.78724 -12.58759 -32.73790 1.000 18.64868 ? 25  LYS B CB  1 
ATOM   195  C CG  . LYS A  1 27 ? -25.00618 -11.88598 -33.32077 1.000 32.62574 ? 25  LYS B CG  1 
ATOM   196  C CD  . LYS A  1 27 ? -25.49318 -12.60573 -34.57273 1.000 36.48240 ? 25  LYS B CD  1 
ATOM   197  C CE  . LYS A  1 27 ? -26.69079 -11.90995 -35.20790 1.000 41.73087 ? 25  LYS B CE  1 
ATOM   198  N NZ  . LYS A  1 27 ? -26.30704 -10.68638 -35.97330 1.000 26.69105 ? 25  LYS B NZ  1 
ATOM   199  N N   . ILE A  1 28 ? -21.95478 -9.91657  -33.34593 1.000 12.31214 ? 26  ILE B N   1 
ATOM   200  C CA  . ILE A  1 28 ? -21.47358 -8.67737  -32.74115 1.000 12.29035 ? 26  ILE B CA  1 
ATOM   201  C C   . ILE A  1 28 ? -22.66539 -7.90461  -32.20472 1.000 11.38925 ? 26  ILE B C   1 
ATOM   202  O O   . ILE A  1 28 ? -23.61940 -7.63379  -32.94393 1.000 13.38475 ? 26  ILE B O   1 
ATOM   203  C CB  . ILE A  1 28 ? -20.70649 -7.80297  -33.74508 1.000 11.30431 ? 26  ILE B CB  1 
ATOM   204  C CG1 . ILE A  1 28 ? -19.48772 -8.53840  -34.28308 1.000 13.09557 ? 26  ILE B CG1 1 
ATOM   205  C CG2 . ILE A  1 28 ? -20.30352 -6.47951  -33.08767 1.000 12.45458 ? 26  ILE B CG2 1 
ATOM   206  C CD1 . ILE A  1 28 ? -18.95793 -7.91989  -35.54833 1.000 13.39703 ? 26  ILE B CD1 1 
ATOM   207  N N   . THR A  1 29 ? -22.59352 -7.52129  -30.93630 1.000 10.60324 ? 27  THR B N   1 
ATOM   208  C CA  . THR A  1 29 ? -23.59144 -6.67506  -30.31078 1.000 10.63676 ? 27  THR B CA  1 
ATOM   209  C C   . THR A  1 29 ? -22.91148 -5.42403  -29.77241 1.000 9.78868  ? 27  THR B C   1 
ATOM   210  O O   . THR A  1 29 ? -21.68100 -5.34736  -29.68320 1.000 11.08432 ? 27  THR B O   1 
ATOM   211  C CB  . THR A  1 29 ? -24.32513 -7.43089  -29.19635 1.000 13.39506 ? 27  THR B CB  1 
ATOM   212  O OG1 . THR A  1 29 ? -23.37353 -7.95234  -28.26657 1.000 15.62090 ? 27  THR B OG1 1 
ATOM   213  C CG2 . THR A  1 29 ? -25.13930 -8.58367  -29.78477 1.000 18.01358 ? 27  THR B CG2 1 
ATOM   214  N N   . GLU A  1 30 ? -23.73189 -4.44412  -29.39562 1.000 9.01822  ? 28  GLU B N   1 
ATOM   215  C CA  . GLU A  1 30 ? -23.27099 -3.09889  -29.07188 1.000 9.15361  ? 28  GLU B CA  1 
ATOM   216  C C   . GLU A  1 30 ? -23.83677 -2.65315  -27.73323 1.000 9.86429  ? 28  GLU B C   1 
ATOM   217  O O   . GLU A  1 30 ? -25.04561 -2.76346  -27.50061 1.000 9.75072  ? 28  GLU B O   1 
ATOM   218  C CB  . GLU A  1 30 ? -23.72932 -2.12534  -30.15960 1.000 9.65704  ? 28  GLU B CB  1 
ATOM   219  C CG  . GLU A  1 30 ? -23.28517 -0.69201  -29.98005 1.000 9.87351  ? 28  GLU B CG  1 
ATOM   220  C CD  . GLU A  1 30 ? -23.96707 0.23628   -30.97206 1.000 9.89145  ? 28  GLU B CD  1 
ATOM   221  O OE1 . GLU A  1 30 ? -25.19790 0.10617   -31.16197 1.000 10.68375 ? 28  GLU B OE1 1 
ATOM   222  O OE2 . GLU A  1 30 ? -23.28348 1.09294   -31.57754 1.000 10.77051 ? 28  GLU B OE2 1 
ATOM   223  N N   . ARG A  1 31 ? -22.96919 -2.14034  -26.86518 1.000 9.05359  ? 29  ARG B N   1 
ATOM   224  C CA  . ARG A  1 31 ? -23.37202 -1.49013  -25.62747 1.000 8.20916  ? 29  ARG B CA  1 
ATOM   225  C C   . ARG A  1 31 ? -22.95236 -0.02810  -25.68502 1.000 8.45402  ? 29  ARG B C   1 
ATOM   226  O O   . ARG A  1 31 ? -21.89824 0.31155   -26.24688 1.000 9.12828  ? 29  ARG B O   1 
ATOM   227  C CB  . ARG A  1 31 ? -22.76016 -2.18400  -24.41072 1.000 9.63129  ? 29  ARG B CB  1 
ATOM   228  C CG  . ARG A  1 31 ? -23.28363 -3.60428  -24.22874 1.000 9.89209  ? 29  ARG B CG  1 
ATOM   229  C CD  . ARG A  1 31 ? -24.69515 -3.62072  -23.64513 1.000 10.30783 ? 29  ARG B CD  1 
ATOM   230  N NE  . ARG A  1 31 ? -24.67025 -3.40669  -22.20016 1.000 9.70506  ? 29  ARG B NE  1 
ATOM   231  C CZ  . ARG A  1 31 ? -25.75133 -3.25646  -21.44410 1.000 10.12052 ? 29  ARG B CZ  1 
ATOM   232  N NH1 . ARG A  1 31 ? -26.96278 -3.20674  -21.97457 1.000 10.68285 ? 29  ARG B NH1 1 
ATOM   233  N NH2 . ARG A  1 31 ? -25.61297 -3.15603  -20.12317 1.000 10.09969 ? 29  ARG B NH2 1 
ATOM   234  N N   . CYS A  1 32 ? -23.77293 0.83228   -25.08153 1.000 8.49800  ? 30  CYS B N   1 
ATOM   235  C CA  . CYS A  1 32 ? -23.67408 2.26839   -25.26097 1.000 9.13722  ? 30  CYS B CA  1 
ATOM   236  C C   . CYS A  1 32 ? -23.72287 2.97104   -23.91870 1.000 8.07026  ? 30  CYS B C   1 
ATOM   237  O O   . CYS A  1 32 ? -24.46596 2.56990   -23.01866 1.000 8.46239  ? 30  CYS B O   1 
ATOM   238  C CB  . CYS A  1 32 ? -24.87064 2.79573   -26.05841 1.000 9.34487  ? 30  CYS B CB  1 
ATOM   239  S SG  . CYS A  1 32 ? -25.21618 1.91823   -27.58844 1.000 9.73602  ? 30  CYS B SG  1 
ATOM   240  N N   . TRP A  1 33 ? -22.98426 4.06829   -23.82903 1.000 8.26961  ? 31  TRP B N   1 
ATOM   241  C CA  . TRP A  1 33 ? -22.96921 4.93603   -22.66318 1.000 9.27350  ? 31  TRP B CA  1 
ATOM   242  C C   . TRP A  1 33 ? -22.97820 6.36969   -23.16625 1.000 8.85037  ? 31  TRP B C   1 
ATOM   243  O O   . TRP A  1 33 ? -22.21744 6.70312   -24.07665 1.000 10.02758 ? 31  TRP B O   1 
ATOM   244  C CB  . TRP A  1 33 ? -21.68431 4.69441   -21.86536 1.000 9.56873  ? 31  TRP B CB  1 
ATOM   245  C CG  . TRP A  1 33 ? -21.47313 5.66138   -20.75478 1.000 12.77836 ? 31  TRP B CG  1 
ATOM   246  C CD1 . TRP A  1 33 ? -20.82533 6.86376   -20.81774 1.000 14.36403 ? 31  TRP B CD1 1 
ATOM   247  C CD2 . TRP A  1 33 ? -21.90505 5.50663   -19.40521 1.000 12.77726 ? 31  TRP B CD2 1 
ATOM   248  N NE1 . TRP A  1 33 ? -20.83774 7.46846   -19.58285 1.000 14.70672 ? 31  TRP B NE1 1 
ATOM   249  C CE2 . TRP A  1 33 ? -21.49808 6.65659   -18.69756 1.000 11.27937 ? 31  TRP B CE2 1 
ATOM   250  C CE3 . TRP A  1 33 ? -22.60185 4.51046   -18.72624 1.000 12.01328 ? 31  TRP B CE3 1 
ATOM   251  C CZ2 . TRP A  1 33 ? -21.76070 6.83075   -17.34125 1.000 16.86553 ? 31  TRP B CZ2 1 
ATOM   252  C CZ3 . TRP A  1 33 ? -22.85674 4.68180   -17.37561 1.000 15.09265 ? 31  TRP B CZ3 1 
ATOM   253  C CH2 . TRP A  1 33 ? -22.43852 5.83162   -16.69877 1.000 14.47727 ? 31  TRP B CH2 1 
ATOM   254  N N   . ASP A  1 34 ? -23.84299 7.21339   -22.59883 1.000 9.74281  ? 32  ASP B N   1 
ATOM   255  C CA  . ASP A  1 34 ? -23.80405 8.64631   -22.87588 1.000 11.65230 ? 32  ASP B CA  1 
ATOM   256  C C   . ASP A  1 34 ? -24.02743 9.41538   -21.59151 1.000 13.53458 ? 32  ASP B C   1 
ATOM   257  O O   . ASP A  1 34 ? -24.74074 10.42301  -21.56540 1.000 15.66846 ? 32  ASP B O   1 
ATOM   258  C CB  . ASP A  1 34 ? -24.82266 9.08153   -23.93113 1.000 13.27984 ? 32  ASP B CB  1 
ATOM   259  C CG  . ASP A  1 34 ? -24.97784 8.08427   -25.05556 1.000 12.33734 ? 32  ASP B CG  1 
ATOM   260  O OD1 . ASP A  1 34 ? -24.22474 8.15055   -26.05582 1.000 11.42922 ? 32  ASP B OD1 1 
ATOM   261  O OD2 . ASP A  1 34 ? -25.88236 7.24020   -24.93220 1.000 15.12175 ? 32  ASP B OD2 1 
ATOM   262  N N   . GLY A  1 35 ? -23.44692 8.92318   -20.50099 1.000 13.48344 ? 33  GLY B N   1 
ATOM   263  C CA  . GLY A  1 35 ? -23.43609 9.62700   -19.24055 1.000 17.47504 ? 33  GLY B CA  1 
ATOM   264  C C   . GLY A  1 35 ? -24.49148 9.21439   -18.23813 1.000 15.56804 ? 33  GLY B C   1 
ATOM   265  O O   . GLY A  1 35 ? -24.48228 9.73770   -17.11667 1.000 20.79478 ? 33  GLY B O   1 
ATOM   266  N N   . LYS A  1 36 ? -25.39420 8.30215   -18.58028 1.000 12.84011 ? 34  LYS B N   1 
ATOM   267  C CA  . LYS A  1 36 ? -26.47405 7.96820   -17.65050 1.000 12.43448 ? 34  LYS B CA  1 
ATOM   268  C C   . LYS A  1 36 ? -26.89735 6.50107   -17.74561 1.000 18.90581 ? 34  LYS B C   1 
ATOM   269  O O   . LYS A  1 36 ? -28.08441 6.16810   -17.75885 1.000 19.06363 ? 34  LYS B O   1 
ATOM   270  C CB  . LYS A  1 36 ? -27.65371 8.93318   -17.77881 1.000 26.99800 ? 34  LYS B CB  1 
ATOM   271  C CG  . LYS A  1 36 ? -28.37741 8.91020   -19.10611 1.000 25.25723 ? 34  LYS B CG  1 
ATOM   272  C CD  . LYS A  1 36 ? -29.75032 9.55108   -18.95149 1.000 38.05807 ? 34  LYS B CD  1 
ATOM   273  C CE  . LYS A  1 36 ? -30.55145 9.50317   -20.23977 1.000 37.15939 ? 34  LYS B CE  1 
ATOM   274  N NZ  . LYS A  1 36 ? -31.87576 10.17261  -20.07836 1.000 36.65881 ? 34  LYS B NZ  1 
ATOM   275  N N   . GLY A  1 37 ? -25.92997 5.60382   -17.76654 1.000 14.42227 ? 35  GLY B N   1 
ATOM   276  C CA  . GLY A  1 37 ? -26.19968 4.17934   -17.71598 1.000 11.10768 ? 35  GLY B CA  1 
ATOM   277  C C   . GLY A  1 37 ? -25.87164 3.49985   -19.03198 1.000 9.45638  ? 35  GLY B C   1 
ATOM   278  O O   . GLY A  1 37 ? -26.04347 4.07250   -20.11681 1.000 10.66444 ? 35  GLY B O   1 
ATOM   279  N N   . TRP A  1 38 ? -25.39544 2.26472   -18.93964 1.000 8.69197  ? 36  TRP B N   1 
ATOM   280  C CA  . TRP A  1 38 ? -25.15590 1.45671   -20.12266 1.000 8.64181  ? 36  TRP B CA  1 
ATOM   281  C C   . TRP A  1 38 ? -26.45831 0.86593   -20.63571 1.000 8.65876  ? 36  TRP B C   1 
ATOM   282  O O   . TRP A  1 38 ? -27.33346 0.47264   -19.85442 1.000 10.23980 ? 36  TRP B O   1 
ATOM   283  C CB  . TRP A  1 38 ? -24.17625 0.33232   -19.80546 1.000 9.16351  ? 36  TRP B CB  1 
ATOM   284  C CG  . TRP A  1 38 ? -22.78975 0.85369   -19.61794 1.000 8.99034  ? 36  TRP B CG  1 
ATOM   285  C CD1 . TRP A  1 38 ? -22.20336 1.23943   -18.45024 1.000 9.59052  ? 36  TRP B CD1 1 
ATOM   286  C CD2 . TRP A  1 38 ? -21.81890 1.08293   -20.64656 1.000 8.22541  ? 36  TRP B CD2 1 
ATOM   287  N NE1 . TRP A  1 38 ? -20.92253 1.68669   -18.68672 1.000 8.37405  ? 36  TRP B NE1 1 
ATOM   288  C CE2 . TRP A  1 38 ? -20.66365 1.59556   -20.02946 1.000 8.76027  ? 36  TRP B CE2 1 
ATOM   289  C CE3 . TRP A  1 38 ? -21.81373 0.89089   -22.03192 1.000 8.48509  ? 36  TRP B CE3 1 
ATOM   290  C CZ2 . TRP A  1 38 ? -19.51723 1.92476   -20.75126 1.000 8.41081  ? 36  TRP B CZ2 1 
ATOM   291  C CZ3 . TRP A  1 38 ? -20.66958 1.21962   -22.74712 1.000 8.26998  ? 36  TRP B CZ3 1 
ATOM   292  C CH2 . TRP A  1 38 ? -19.54021 1.72635   -22.10378 1.000 9.21429  ? 36  TRP B CH2 1 
ATOM   293  N N   . TYR A  1 39 ? -26.57057 0.77863   -21.95726 1.000 8.73676  ? 37  TYR B N   1 
ATOM   294  C CA  . TYR A  1 39 ? -27.75204 0.22933   -22.59616 1.000 8.90475  ? 37  TYR B CA  1 
ATOM   295  C C   . TYR A  1 39 ? -27.33502 -0.43128  -23.90284 1.000 8.97592  ? 37  TYR B C   1 
ATOM   296  O O   . TYR A  1 39 ? -26.22905 -0.21756  -24.40846 1.000 10.29368 ? 37  TYR B O   1 
ATOM   297  C CB  . TYR A  1 39 ? -28.82307 1.30992   -22.80964 1.000 10.29155 ? 37  TYR B CB  1 
ATOM   298  C CG  . TYR A  1 39 ? -28.39085 2.45114   -23.70471 1.000 10.09023 ? 37  TYR B CG  1 
ATOM   299  C CD1 . TYR A  1 39 ? -27.65113 3.51219   -23.20821 1.000 9.69312  ? 37  TYR B CD1 1 
ATOM   300  C CD2 . TYR A  1 39 ? -28.73632 2.46748   -25.04867 1.000 9.66785  ? 37  TYR B CD2 1 
ATOM   301  C CE1 . TYR A  1 39 ? -27.24613 4.54885   -24.03079 1.000 9.77656  ? 37  TYR B CE1 1 
ATOM   302  C CE2 . TYR A  1 39 ? -28.34533 3.50336   -25.87771 1.000 10.57682 ? 37  TYR B CE2 1 
ATOM   303  C CZ  . TYR A  1 39 ? -27.60699 4.53909   -25.36548 1.000 9.80992  ? 37  TYR B CZ  1 
ATOM   304  O OH  . TYR A  1 39 ? -27.21196 5.56001   -26.19861 1.000 11.68167 ? 37  TYR B OH  1 
ATOM   305  N N   . THR A  1 40 ? -28.22149 -1.24844  -24.44258 1.000 9.54142  ? 38  THR B N   1 
ATOM   306  C CA  . THR A  1 40 ? -27.93185 -1.98149  -25.66313 1.000 9.64478  ? 38  THR B CA  1 
ATOM   307  C C   . THR A  1 40 ? -28.29552 -1.14011  -26.87586 1.000 9.71952  ? 38  THR B C   1 
ATOM   308  O O   . THR A  1 40 ? -29.38769 -0.56922  -26.94221 1.000 11.84914 ? 38  THR B O   1 
ATOM   309  C CB  . THR A  1 40 ? -28.69872 -3.30039  -25.65705 1.000 11.38287 ? 38  THR B CB  1 
ATOM   310  O OG1 . THR A  1 40 ? -28.23375 -4.08289  -24.55261 1.000 13.46484 ? 38  THR B OG1 1 
ATOM   311  C CG2 . THR A  1 40 ? -28.47246 -4.07401  -26.94852 1.000 11.98614 ? 38  THR B CG2 1 
ATOM   312  N N   . GLY A  1 41 ? -27.36274 -1.04034  -27.82230 1.000 10.07178 ? 39  GLY B N   1 
ATOM   313  C CA  . GLY A  1 41 ? -27.56545 -0.24278  -29.01019 1.000 10.68058 ? 39  GLY B CA  1 
ATOM   314  C C   . GLY A  1 41 ? -28.18315 -1.02140  -30.15121 1.000 10.86697 ? 39  GLY B C   1 
ATOM   315  O O   . GLY A  1 41 ? -28.38054 -2.23441  -30.09241 1.000 11.36619 ? 39  GLY B O   1 
ATOM   316  N N   . ALA A  1 42 ? -28.47564 -0.28470  -31.22420 1.000 11.55595 ? 40  ALA B N   1 
ATOM   317  C CA  . ALA A  1 42 ? -29.13513 -0.86685  -32.38415 1.000 12.85512 ? 40  ALA B CA  1 
ATOM   318  C C   . ALA A  1 42 ? -28.23054 -1.78885  -33.19417 1.000 14.40849 ? 40  ALA B C   1 
ATOM   319  O O   . ALA A  1 42 ? -28.74361 -2.60181  -33.96989 1.000 15.64262 ? 40  ALA B O   1 
ATOM   320  C CB  . ALA A  1 42 ? -29.66995 0.24153   -33.28797 1.000 14.32922 ? 40  ALA B CB  1 
ATOM   321  N N   . PHE A  1 43 ? -26.90886 -1.69723  -33.04127 1.000 12.03285 ? 41  PHE B N   1 
ATOM   322  C CA  . PHE A  1 43 ? -26.02453 -2.46159  -33.91264 1.000 13.57019 ? 41  PHE B CA  1 
ATOM   323  C C   . PHE A  1 43 ? -26.08111 -3.94519  -33.57055 1.000 12.15018 ? 41  PHE B C   1 
ATOM   324  O O   . PHE A  1 43 ? -25.80131 -4.34712  -32.43616 1.000 12.42624 ? 41  PHE B O   1 
ATOM   325  C CB  . PHE A  1 43 ? -24.58696 -1.96588  -33.82705 1.000 12.07983 ? 41  PHE B CB  1 
ATOM   326  C CG  . PHE A  1 43 ? -23.67004 -2.67541  -34.77938 1.000 10.34664 ? 41  PHE B CG  1 
ATOM   327  C CD1 . PHE A  1 43 ? -23.05473 -3.86129  -34.42528 1.000 11.61959 ? 41  PHE B CD1 1 
ATOM   328  C CD2 . PHE A  1 43 ? -23.45949 -2.17821  -36.04606 1.000 13.41929 ? 41  PHE B CD2 1 
ATOM   329  C CE1 . PHE A  1 43 ? -22.22984 -4.52945  -35.30959 1.000 12.28285 ? 41  PHE B CE1 1 
ATOM   330  C CE2 . PHE A  1 43 ? -22.62940 -2.84438  -36.93921 1.000 12.36469 ? 41  PHE B CE2 1 
ATOM   331  C CZ  . PHE A  1 43 ? -22.02208 -4.02409  -36.56804 1.000 12.74077 ? 41  PHE B CZ  1 
ATOM   332  N N   . ASN A  1 44 ? -26.39755 -4.76676  -34.56357 1.000 13.75510 ? 42  ASN B N   1 
ATOM   333  C CA  . ASN A  1 44 ? -26.40131 -6.21215  -34.37662 1.000 13.54837 ? 42  ASN B CA  1 
ATOM   334  C C   . ASN A  1 44 ? -26.12451 -6.82693  -35.74014 1.000 15.64214 ? 42  ASN B C   1 
ATOM   335  O O   . ASN A  1 44 ? -26.97771 -6.76144  -36.62873 1.000 15.99430 ? 42  ASN B O   1 
ATOM   336  C CB  . ASN A  1 44 ? -27.74836 -6.66970  -33.81887 1.000 16.66121 ? 42  ASN B CB  1 
ATOM   337  C CG  . ASN A  1 44 ? -27.74883 -8.12685  -33.41622 1.000 21.41335 ? 42  ASN B CG  1 
ATOM   338  O OD1 . ASN A  1 44 ? -27.40450 -9.00255  -34.20787 1.000 25.39275 ? 42  ASN B OD1 1 
ATOM   339  N ND2 . ASN A  1 44 ? -28.13403 -8.39646  -32.17457 1.000 26.80327 ? 42  ASN B ND2 1 
ATOM   340  N N   . GLU A  1 45 ? -24.93338 -7.39044  -35.91805 1.000 12.11446 ? 43  GLU B N   1 
ATOM   341  C CA  . GLU A  1 45 ? -24.53330 -7.94078  -37.20433 1.000 12.75465 ? 43  GLU B CA  1 
ATOM   342  C C   . GLU A  1 45 ? -23.65870 -9.15627  -36.96328 1.000 12.69173 ? 43  GLU B C   1 
ATOM   343  O O   . GLU A  1 45 ? -23.01307 -9.26580  -35.91486 1.000 14.36323 ? 43  GLU B O   1 
ATOM   344  C CB  . GLU A  1 45 ? -23.75959 -6.91865  -38.05162 1.000 13.68595 ? 43  GLU B CB  1 
ATOM   345  C CG  . GLU A  1 45 ? -24.51925 -5.64421  -38.40945 1.000 15.93739 ? 43  GLU B CG  1 
ATOM   346  C CD  . GLU A  1 45 ? -25.73078 -5.88199  -39.29418 1.000 17.25072 ? 43  GLU B CD  1 
ATOM   347  O OE1 . GLU A  1 45 ? -25.89489 -7.00229  -39.82556 1.000 19.07426 ? 43  GLU B OE1 1 
ATOM   348  O OE2 . GLU A  1 45 ? -26.52388 -4.93158  -39.45945 1.000 21.20264 ? 43  GLU B OE2 1 
ATOM   349  N N   . PRO A  1 46 ? -23.60267 -10.07964 -37.91962 1.000 13.83990 ? 44  PRO B N   1 
ATOM   350  C CA  . PRO A  1 46 ? -22.71216 -11.23416 -37.78148 1.000 15.42738 ? 44  PRO B CA  1 
ATOM   351  C C   . PRO A  1 46 ? -21.24765 -10.82191 -37.79120 1.000 13.18804 ? 44  PRO B C   1 
ATOM   352  O O   . PRO A  1 46 ? -20.84088 -9.87839  -38.47703 1.000 14.12447 ? 44  PRO B O   1 
ATOM   353  C CB  . PRO A  1 46 ? -23.03910 -12.08144 -39.01731 1.000 20.50577 ? 44  PRO B CB  1 
ATOM   354  C CG  . PRO A  1 46 ? -24.39448 -11.62703 -39.45478 1.000 19.12224 ? 44  PRO B CG  1 
ATOM   355  C CD  . PRO A  1 46 ? -24.46495 -10.17639 -39.10910 1.000 15.70498 ? 44  PRO B CD  1 
ATOM   356  N N   . GLY A  1 47 ? -20.45193 -11.56131 -37.02164 1.000 13.32603 ? 45  GLY B N   1 
ATOM   357  C CA  . GLY A  1 47 ? -19.01605 -11.38042 -37.00201 1.000 14.78122 ? 45  GLY B CA  1 
ATOM   358  C C   . GLY A  1 47 ? -18.33526 -12.14202 -35.88460 1.000 12.09563 ? 45  GLY B C   1 
ATOM   359  O O   . GLY A  1 47 ? -18.86310 -12.22546 -34.77043 1.000 13.56767 ? 45  GLY B O   1 
ATOM   360  N N   . ASP A  1 48 ? -17.16777 -12.71170 -36.18105 1.000 12.29997 ? 46  ASP B N   1 
ATOM   361  C CA  . ASP A  1 48 ? -16.28345 -13.28162 -35.17615 1.000 13.58503 ? 46  ASP B CA  1 
ATOM   362  C C   . ASP A  1 48 ? -15.24003 -12.28912 -34.68379 1.000 11.60303 ? 46  ASP B C   1 
ATOM   363  O O   . ASP A  1 48 ? -14.60767 -12.53311 -33.65069 1.000 13.49377 ? 46  ASP B O   1 
ATOM   364  C CB  . ASP A  1 48 ? -15.54940 -14.49605 -35.75494 1.000 18.76001 ? 46  ASP B CB  1 
ATOM   365  C CG  . ASP A  1 48 ? -16.48179 -15.64328 -36.08376 1.000 26.23146 ? 46  ASP B CG  1 
ATOM   366  O OD1 . ASP A  1 48 ? -17.34846 -15.96491 -35.24345 1.000 29.74865 ? 46  ASP B OD1 1 
ATOM   367  O OD2 . ASP A  1 48 ? -16.34372 -16.22627 -37.18056 1.000 27.01955 ? 46  ASP B OD2 1 
ATOM   368  N N   . ASN A  1 49 ? -15.03860 -11.18290 -35.40364 1.000 11.41795 ? 47  ASN B N   1 
ATOM   369  C CA  . ASN A  1 49 ? -14.05602 -10.17460 -35.04694 1.000 10.41733 ? 47  ASN B CA  1 
ATOM   370  C C   . ASN A  1 49 ? -14.62853 -8.81303  -35.40498 1.000 9.66398  ? 47  ASN B C   1 
ATOM   371  O O   . ASN A  1 49 ? -15.32833 -8.67138  -36.41305 1.000 9.70145  ? 47  ASN B O   1 
ATOM   372  C CB  . ASN A  1 49 ? -12.74985 -10.39407 -35.82006 1.000 10.74597 ? 47  ASN B CB  1 
ATOM   373  C CG  . ASN A  1 49 ? -11.72298 -9.30838  -35.55795 1.000 10.78455 ? 47  ASN B CG  1 
ATOM   374  O OD1 . ASN A  1 49 ? -11.62666 -8.32915  -36.30815 1.000 9.97308  ? 47  ASN B OD1 1 
ATOM   375  N ND2 . ASN A  1 49 ? -10.94192 -9.47700  -34.49777 1.000 11.29926 ? 47  ASN B ND2 1 
ATOM   376  N N   . VAL A  1 50 ? -14.32915 -7.81403  -34.57880 1.000 8.96944  ? 48  VAL B N   1 
ATOM   377  C CA  . VAL A  1 50 ? -14.83320 -6.46534  -34.79525 1.000 8.68773  ? 48  VAL B CA  1 
ATOM   378  C C   . VAL A  1 50 ? -13.71995 -5.45475  -34.54598 1.000 7.96475  ? 48  VAL B C   1 
ATOM   379  O O   . VAL A  1 50 ? -12.91409 -5.60088  -33.61950 1.000 9.17251  ? 48  VAL B O   1 
ATOM   380  C CB  . VAL A  1 50 ? -16.06699 -6.19019  -33.90249 1.000 8.76871  ? 48  VAL B CB  1 
ATOM   381  C CG1 . VAL A  1 50 ? -15.72365 -6.32591  -32.40194 1.000 10.34186 ? 48  VAL B CG1 1 
ATOM   382  C CG2 . VAL A  1 50 ? -16.66557 -4.82685  -34.21371 1.000 9.44610  ? 48  VAL B CG2 1 
ATOM   383  N N   . SER A  1 51 ? -13.68021 -4.42287  -35.38422 1.000 7.70793  ? 49  SER B N   1 
ATOM   384  C CA  . SER A  1 51 ? -12.95474 -3.20327  -35.07275 1.000 8.39588  ? 49  SER B CA  1 
ATOM   385  C C   . SER A  1 51 ? -13.87448 -2.02521  -35.35517 1.000 7.39673  ? 49  SER B C   1 
ATOM   386  O O   . SER A  1 51 ? -14.88765 -2.15593  -36.04585 1.000 7.74434  ? 49  SER B O   1 
ATOM   387  C CB  . SER A  1 51 ? -11.63615 -3.06985  -35.85474 1.000 7.59438  ? 49  SER B CB  1 
ATOM   388  O OG  . SER A  1 51 ? -11.86778 -2.90149  -37.24117 1.000 8.47008  ? 49  SER B OG  1 
ATOM   389  N N   . VAL A  1 52 ? -13.51498 -0.86571  -34.81478 1.000 7.68307  ? 50  VAL B N   1 
ATOM   390  C CA  . VAL A  1 52 ? -14.34612 0.32087   -34.95843 1.000 7.31597  ? 50  VAL B CA  1 
ATOM   391  C C   . VAL A  1 52 ? -13.47079 1.56377   -35.01158 1.000 6.61347  ? 50  VAL B C   1 
ATOM   392  O O   . VAL A  1 52 ? -12.40149 1.62351   -34.40386 1.000 8.53902  ? 50  VAL B O   1 
ATOM   393  C CB  . VAL A  1 52 ? -15.38604 0.40710   -33.81300 1.000 7.61055  ? 50  VAL B CB  1 
ATOM   394  C CG1 . VAL A  1 52 ? -14.70424 0.54165   -32.45403 1.000 8.89215  ? 50  VAL B CG1 1 
ATOM   395  C CG2 . VAL A  1 52 ? -16.34971 1.55889   -34.04341 1.000 8.33554  ? 50  VAL B CG2 1 
ATOM   396  N N   . THR A  1 53 ? -13.94881 2.57327   -35.73081 1.000 8.06962  ? 51  THR B N   1 
ATOM   397  C CA  . THR A  1 53 ? -13.39210 3.91219   -35.66793 1.000 8.26984  ? 51  THR B CA  1 
ATOM   398  C C   . THR A  1 53 ? -14.54283 4.89685   -35.81855 1.000 8.79481  ? 51  THR B C   1 
ATOM   399  O O   . THR A  1 53 ? -15.61361 4.55166   -36.31818 1.000 9.17995  ? 51  THR B O   1 
ATOM   400  C CB  . THR A  1 53 ? -12.29129 4.10748   -36.72527 1.000 8.40786  ? 51  THR B CB  1 
ATOM   401  O OG1 . THR A  1 53 ? -11.61851 5.35111   -36.50387 1.000 9.78489  ? 51  THR B OG1 1 
ATOM   402  C CG2 . THR A  1 53 ? -12.86235 4.09319   -38.13806 1.000 9.78244  ? 51  THR B CG2 1 
ATOM   403  N N   . SER A  1 54 ? -14.33073 6.12834   -35.36392 1.000 9.17419  ? 52  SER B N   1 
ATOM   404  C CA  . SER A  1 54 ? -15.36973 7.14450   -35.47382 1.000 9.02068  ? 52  SER B CA  1 
ATOM   405  C C   . SER A  1 54 ? -14.71773 8.51350   -35.58468 1.000 9.85845  ? 52  SER B C   1 
ATOM   406  O O   . SER A  1 54 ? -13.57653 8.71081   -35.16700 1.000 10.47434 ? 52  SER B O   1 
ATOM   407  C CB  . SER A  1 54 ? -16.35757 7.09178   -34.29491 1.000 9.76886  ? 52  SER B CB  1 
ATOM   408  O OG  . SER A  1 54 ? -15.73244 7.43745   -33.07101 1.000 10.43606 ? 52  SER B OG  1 
ATOM   409  N N   . TRP A  1 55 ? -15.45774 9.45586   -36.16403 1.000 9.51595  ? 53  TRP B N   1 
ATOM   410  C CA  . TRP A  1 55 ? -14.97996 10.82199  -36.31642 1.000 9.98602  ? 53  TRP B CA  1 
ATOM   411  C C   . TRP A  1 55 ? -16.17223 11.76273  -36.26062 1.000 11.42506 ? 53  TRP B C   1 
ATOM   412  O O   . TRP A  1 55 ? -17.29848 11.38117  -36.58094 1.000 12.46363 ? 53  TRP B O   1 
ATOM   413  C CB  . TRP A  1 55 ? -14.21892 11.04301  -37.63896 1.000 12.08021 ? 53  TRP B CB  1 
ATOM   414  C CG  . TRP A  1 55 ? -15.06722 10.84337  -38.85649 1.000 10.30898 ? 53  TRP B CG  1 
ATOM   415  C CD1 . TRP A  1 55 ? -15.74538 11.80445  -39.56099 1.000 11.49615 ? 53  TRP B CD1 1 
ATOM   416  C CD2 . TRP A  1 55 ? -15.35186 9.60000   -39.50622 1.000 10.43308 ? 53  TRP B CD2 1 
ATOM   417  N NE1 . TRP A  1 55 ? -16.42325 11.23341  -40.60513 1.000 11.31987 ? 53  TRP B NE1 1 
ATOM   418  C CE2 . TRP A  1 55 ? -16.19606 9.88195   -40.59538 1.000 9.75373  ? 53  TRP B CE2 1 
ATOM   419  C CE3 . TRP A  1 55 ? -14.95667 8.27732   -39.28475 1.000 8.44527  ? 53  TRP B CE3 1 
ATOM   420  C CZ2 . TRP A  1 55 ? -16.67237 8.89184   -41.44327 1.000 10.97497 ? 53  TRP B CZ2 1 
ATOM   421  C CZ3 . TRP A  1 55 ? -15.42635 7.29544   -40.13475 1.000 9.57911  ? 53  TRP B CZ3 1 
ATOM   422  C CH2 . TRP A  1 55 ? -16.27138 7.60783   -41.20231 1.000 9.56808  ? 53  TRP B CH2 1 
ATOM   423  N N   . LEU A  1 56 ? -15.90660 13.00169  -35.86480 1.000 13.92246 ? 54  LEU B N   1 
ATOM   424  C CA  . LEU A  1 56 ? -16.91629 14.04818  -35.85542 1.000 14.54575 ? 54  LEU B CA  1 
ATOM   425  C C   . LEU A  1 56 ? -16.79103 14.90354  -37.10763 1.000 17.71236 ? 54  LEU B C   1 
ATOM   426  O O   . LEU A  1 56 ? -15.68326 15.22230  -37.54914 1.000 18.18186 ? 54  LEU B O   1 
ATOM   427  C CB  . LEU A  1 56 ? -16.76089 14.93874  -34.62204 1.000 16.55536 ? 54  LEU B CB  1 
ATOM   428  C CG  . LEU A  1 56 ? -17.14795 14.30061  -33.28810 1.000 15.50293 ? 54  LEU B CG  1 
ATOM   429  C CD1 . LEU A  1 56 ? -16.56507 15.10135  -32.14078 1.000 20.00041 ? 54  LEU B CD1 1 
ATOM   430  C CD2 . LEU A  1 56 ? -18.66030 14.19631  -33.15656 1.000 17.58321 ? 54  LEU B CD2 1 
ATOM   431  N N   . VAL A  1 57 ? -17.93318 15.24640  -37.68708 1.000 16.16307 ? 55  VAL B N   1 
ATOM   432  C CA  . VAL A  1 57 ? -18.04165 16.31982  -38.66667 1.000 18.61507 ? 55  VAL B CA  1 
ATOM   433  C C   . VAL A  1 57 ? -18.85054 17.40962  -37.97619 1.000 22.67736 ? 55  VAL B C   1 
ATOM   434  O O   . VAL A  1 57 ? -20.07958 17.31907  -37.87542 1.000 22.08691 ? 55  VAL B O   1 
ATOM   435  C CB  . VAL A  1 57 ? -18.70005 15.85276  -39.96907 1.000 21.21236 ? 55  VAL B CB  1 
ATOM   436  C CG1 . VAL A  1 57 ? -18.81353 17.00993  -40.95076 1.000 24.64082 ? 55  VAL B CG1 1 
ATOM   437  C CG2 . VAL A  1 57 ? -17.90057 14.71312  -40.58785 1.000 21.06975 ? 55  VAL B CG2 1 
ATOM   438  N N   . GLY A  1 58 ? -18.15965 18.42626  -37.46824 1.000 28.07485 ? 56  GLY B N   1 
ATOM   439  C CA  . GLY A  1 58 ? -18.79679 19.39948  -36.60629 1.000 28.79393 ? 56  GLY B CA  1 
ATOM   440  C C   . GLY A  1 58 ? -19.31362 18.74818  -35.33983 1.000 22.68461 ? 56  GLY B C   1 
ATOM   441  O O   . GLY A  1 58 ? -18.52774 18.33269  -34.48195 1.000 27.67758 ? 56  GLY B O   1 
ATOM   442  N N   . SER A  1 59 ? -20.63619 18.63761  -35.22092 1.000 21.23022 ? 57  SER B N   1 
ATOM   443  C CA  . SER A  1 59 ? -21.27084 18.02186  -34.06406 1.000 19.04964 ? 57  SER B CA  1 
ATOM   444  C C   . SER A  1 59 ? -21.81745 16.63003  -34.34642 1.000 23.03418 ? 57  SER B C   1 
ATOM   445  O O   . SER A  1 59 ? -22.31898 15.98137  -33.42162 1.000 19.74010 ? 57  SER B O   1 
ATOM   446  C CB  . SER A  1 59 ? -22.40216 18.91587  -33.53610 1.000 20.43219 ? 57  SER B CB  1 
ATOM   447  O OG  . SER A  1 59 ? -21.91243 20.19724  -33.18107 1.000 31.68002 ? 57  SER B OG  1 
ATOM   448  N N   . ALA A  1 60 ? -21.74108 16.15687  -35.58799 1.000 18.76857 ? 58  ALA B N   1 
ATOM   449  C CA  . ALA A  1 60 ? -22.34301 14.89200  -35.98595 1.000 18.77176 ? 58  ALA B CA  1 
ATOM   450  C C   . ALA A  1 60 ? -21.30618 13.77524  -35.93853 1.000 14.53249 ? 58  ALA B C   1 
ATOM   451  O O   . ALA A  1 60 ? -20.21625 13.90063  -36.51033 1.000 16.46161 ? 58  ALA B O   1 
ATOM   452  C CB  . ALA A  1 60 ? -22.93109 14.99956  -37.39293 1.000 25.18308 ? 58  ALA B CB  1 
ATOM   453  N N   . ILE A  1 61 ? -21.65376 12.68113  -35.27056 1.000 14.11001 ? 59  ILE B N   1 
ATOM   454  C CA  . ILE A  1 61 ? -20.76534 11.53077  -35.16014 1.000 12.00465 ? 59  ILE B CA  1 
ATOM   455  C C   . ILE A  1 61 ? -20.97901 10.61327  -36.35409 1.000 12.30414 ? 59  ILE B C   1 
ATOM   456  O O   . ILE A  1 61 ? -22.10235 10.42223  -36.83355 1.000 13.83896 ? 59  ILE B O   1 
ATOM   457  C CB  . ILE A  1 61 ? -20.97524 10.78816  -33.82444 1.000 13.64809 ? 59  ILE B CB  1 
ATOM   458  C CG1 . ILE A  1 61 ? -19.89728 9.71778   -33.63043 1.000 13.70429 ? 59  ILE B CG1 1 
ATOM   459  C CG2 . ILE A  1 61 ? -22.36322 10.17329  -33.75609 1.000 18.64776 ? 59  ILE B CG2 1 
ATOM   460  C CD1 . ILE A  1 61 ? -18.50971 10.28407  -33.46067 1.000 13.74623 ? 59  ILE B CD1 1 
ATOM   461  N N   . HIS A  1 62 ? -19.87729 10.05666  -36.84810 1.000 10.53084 ? 60  HIS B N   1 
ATOM   462  C CA  . HIS A  1 62 ? -19.88756 9.05148   -37.89844 1.000 10.70823 ? 60  HIS B CA  1 
ATOM   463  C C   . HIS A  1 62 ? -19.09267 7.86633   -37.38077 1.000 9.98707  ? 60  HIS B C   1 
ATOM   464  O O   . HIS A  1 62 ? -17.99352 8.04865   -36.85846 1.000 10.80720 ? 60  HIS B O   1 
ATOM   465  C CB  . HIS A  1 62 ? -19.24719 9.62473   -39.16083 1.000 10.40576 ? 60  HIS B CB  1 
ATOM   466  C CG  . HIS A  1 62 ? -20.01991 10.76854  -39.73892 1.000 12.39211 ? 60  HIS B CG  1 
ATOM   467  N ND1 . HIS A  1 62 ? -20.92765 10.60797  -40.76284 1.000 14.04985 ? 60  HIS B ND1 1 
ATOM   468  C CD2 . HIS A  1 62 ? -20.05855 12.07951  -39.40076 1.000 16.23717 ? 60  HIS B CD2 1 
ATOM   469  C CE1 . HIS A  1 62 ? -21.47386 11.77757  -41.04915 1.000 16.97484 ? 60  HIS B CE1 1 
ATOM   470  N NE2 . HIS A  1 62 ? -20.96555 12.68570  -40.23605 1.000 17.18555 ? 60  HIS B NE2 1 
ATOM   471  N N   . ILE A  1 63 ? -19.65633 6.66674   -37.48455 1.000 9.43592  ? 61  ILE B N   1 
ATOM   472  C CA  . ILE A  1 63 ? -19.03731 5.45912   -36.94666 1.000 8.27292  ? 61  ILE B CA  1 
ATOM   473  C C   . ILE A  1 63 ? -18.86987 4.45289   -38.07453 1.000 8.57019  ? 61  ILE B C   1 
ATOM   474  O O   . ILE A  1 63 ? -19.76013 4.30269   -38.91612 1.000 9.09047  ? 61  ILE B O   1 
ATOM   475  C CB  . ILE A  1 63 ? -19.87348 4.83125   -35.81150 1.000 8.61634  ? 61  ILE B CB  1 
ATOM   476  C CG1 . ILE A  1 63 ? -20.29027 5.88120   -34.77549 1.000 10.22647 ? 61  ILE B CG1 1 
ATOM   477  C CG2 . ILE A  1 63 ? -19.08844 3.71658   -35.15060 1.000 9.52106  ? 61  ILE B CG2 1 
ATOM   478  C CD1 . ILE A  1 63 ? -21.34503 5.38071   -33.81282 1.000 11.63288 ? 61  ILE B CD1 1 
ATOM   479  N N   . ARG A  1 64 ? -17.73755 3.74918   -38.07893 1.000 8.17116  ? 62  ARG B N   1 
ATOM   480  C CA  . ARG A  1 64 ? -17.51588 2.63613   -38.99326 1.000 8.15535  ? 62  ARG B CA  1 
ATOM   481  C C   . ARG A  1 64 ? -17.12668 1.41604   -38.17681 1.000 7.70428  ? 62  ARG B C   1 
ATOM   482  O O   . ARG A  1 64 ? -16.16486 1.46082   -37.40333 1.000 8.27203  ? 62  ARG B O   1 
ATOM   483  C CB  . ARG A  1 64 ? -16.42968 2.94655   -40.02715 1.000 8.43531  ? 62  ARG B CB  1 
ATOM   484  C CG  . ARG A  1 64 ? -16.75816 4.11759   -40.93516 1.000 8.19354  ? 62  ARG B CG  1 
ATOM   485  C CD  . ARG A  1 64 ? -17.94170 3.81430   -41.84032 1.000 8.60426  ? 62  ARG B CD  1 
ATOM   486  N NE  . ARG A  1 64 ? -18.24675 4.93842   -42.72228 1.000 8.91118  ? 62  ARG B NE  1 
ATOM   487  C CZ  . ARG A  1 64 ? -19.05599 5.94177   -42.41037 1.000 9.01154  ? 62  ARG B CZ  1 
ATOM   488  N NH1 . ARG A  1 64 ? -19.69916 5.97940   -41.25460 1.000 9.60130  ? 62  ARG B NH1 1 
ATOM   489  N NH2 . ARG A  1 64 ? -19.21549 6.94380   -43.27551 1.000 10.27226 ? 62  ARG B NH2 1 
ATOM   490  N N   . VAL A  1 65 ? -17.87722 0.33672   -38.35132 1.000 7.77019  ? 63  VAL B N   1 
ATOM   491  C CA  . VAL A  1 65 ? -17.62536 -0.93787  -37.69455 1.000 7.40159  ? 63  VAL B CA  1 
ATOM   492  C C   . VAL A  1 65 ? -17.24620 -1.95043  -38.76498 1.000 7.75766  ? 63  VAL B C   1 
ATOM   493  O O   . VAL A  1 65 ? -17.96367 -2.10173  -39.76239 1.000 9.97854  ? 63  VAL B O   1 
ATOM   494  C CB  . VAL A  1 65 ? -18.86605 -1.40747  -36.91518 1.000 9.24690  ? 63  VAL B CB  1 
ATOM   495  C CG1 . VAL A  1 65 ? -18.63181 -2.77457  -36.33507 1.000 9.96983  ? 63  VAL B CG1 1 
ATOM   496  C CG2 . VAL A  1 65 ? -19.20130 -0.42284  -35.81816 1.000 9.75156  ? 63  VAL B CG2 1 
ATOM   497  N N   . TYR A  1 66 ? -16.11821 -2.63581  -38.56211 1.000 7.79818  ? 64  TYR B N   1 
ATOM   498  C CA  . TYR A  1 66 ? -15.59592 -3.62918  -39.50046 1.000 8.35350  ? 64  TYR B CA  1 
ATOM   499  C C   . TYR A  1 66 ? -15.81856 -5.00095  -38.87784 1.000 7.95365  ? 64  TYR B C   1 
ATOM   500  O O   . TYR A  1 66 ? -15.17590 -5.34557  -37.88037 1.000 8.31729  ? 64  TYR B O   1 
ATOM   501  C CB  . TYR A  1 66 ? -14.12345 -3.35202  -39.84579 1.000 8.34746  ? 64  TYR B CB  1 
ATOM   502  C CG  . TYR A  1 66 ? -14.02605 -1.99808  -40.50309 1.000 7.07697  ? 64  TYR B CG  1 
ATOM   503  C CD1 . TYR A  1 66 ? -14.25888 -1.84222  -41.86477 1.000 7.98337  ? 64  TYR B CD1 1 
ATOM   504  C CD2 . TYR A  1 66 ? -13.80926 -0.85640  -39.74837 1.000 7.28032  ? 64  TYR B CD2 1 
ATOM   505  C CE1 . TYR A  1 66 ? -14.24547 -0.59541  -42.45017 1.000 8.07120  ? 64  TYR B CE1 1 
ATOM   506  C CE2 . TYR A  1 66 ? -13.80397 0.39250   -40.32788 1.000 7.54614  ? 64  TYR B CE2 1 
ATOM   507  C CZ  . TYR A  1 66 ? -14.02144 0.51964   -41.67685 1.000 6.90099  ? 64  TYR B CZ  1 
ATOM   508  O OH  . TYR A  1 66 ? -14.03568 1.77671   -42.22168 1.000 7.57920  ? 64  TYR B OH  1 
ATOM   509  N N   . ALA A  1 67 ? -16.74847 -5.76064  -39.45484 1.000 9.12477  ? 65  ALA B N   1 
ATOM   510  C CA  . ALA A  1 67 ? -17.18958 -7.05007  -38.93375 1.000 9.94149  ? 65  ALA B CA  1 
ATOM   511  C C   . ALA A  1 67 ? -16.65474 -8.13984  -39.85030 1.000 10.28932 ? 65  ALA B C   1 
ATOM   512  O O   . ALA A  1 67 ? -16.91453 -8.11176  -41.05608 1.000 10.79072 ? 65  ALA B O   1 
ATOM   513  C CB  . ALA A  1 67 ? -18.71616 -7.10049  -38.93916 1.000 10.29239 ? 65  ALA B CB  1 
ATOM   514  N N   . SER A  1 68 ? -15.92006 -9.10032  -39.29312 1.000 9.62973  ? 66  SER B N   1 
ATOM   515  C CA  . SER A  1 68 ? -15.29383 -10.14141 -40.09895 1.000 9.92872  ? 66  SER B CA  1 
ATOM   516  C C   . SER A  1 68 ? -15.78570 -11.52108 -39.69358 1.000 10.99321 ? 66  SER B C   1 
ATOM   517  O O   . SER A  1 68 ? -15.85202 -11.84074 -38.50214 1.000 11.73241 ? 66  SER B O   1 
ATOM   518  C CB  . SER A  1 68 ? -13.77275 -10.10377 -39.97639 1.000 10.18754 ? 66  SER B CB  1 
ATOM   519  O OG  . SER A  1 68 ? -13.26053 -8.86835  -40.43171 1.000 10.57155 ? 66  SER B OG  1 
ATOM   520  N N   . THR A  1 69 ? -16.11177 -12.33056 -40.69910 1.000 11.36378 ? 67  THR B N   1 
ATOM   521  C CA  . THR A  1 69 ? -16.38947 -13.75027 -40.54769 1.000 13.97594 ? 67  THR B CA  1 
ATOM   522  C C   . THR A  1 69 ? -15.59897 -14.45640 -41.63190 1.000 14.63261 ? 67  THR B C   1 
ATOM   523  O O   . THR A  1 69 ? -15.71614 -14.10395 -42.80905 1.000 14.64587 ? 67  THR B O   1 
ATOM   524  C CB  . THR A  1 69 ? -17.87707 -14.04048 -40.74480 1.000 15.42248 ? 67  THR B CB  1 
ATOM   525  O OG1 . THR A  1 69 ? -18.63849 -13.30300 -39.78463 1.000 18.07538 ? 67  THR B OG1 1 
ATOM   526  C CG2 . THR A  1 69 ? -18.15948 -15.52682 -40.56674 1.000 18.34910 ? 67  THR B CG2 1 
ATOM   527  N N   . GLY A  1 70 ? -14.79180 -15.43482 -41.24010 1.000 14.39303 ? 68  GLY B N   1 
ATOM   528  C CA  . GLY A  1 70 ? -13.89716 -16.04162 -42.21165 1.000 17.03360 ? 68  GLY B CA  1 
ATOM   529  C C   . GLY A  1 70 ? -12.95939 -14.98499 -42.75781 1.000 16.00913 ? 68  GLY B C   1 
ATOM   530  O O   . GLY A  1 70 ? -12.34794 -14.21746 -42.00783 1.000 17.58717 ? 68  GLY B O   1 
ATOM   531  N N   . THR A  1 71 ? -12.85562 -14.90960 -44.07941 1.000 14.83687 ? 69  THR B N   1 
ATOM   532  C CA  . THR A  1 71 ? -12.01873 -13.90715 -44.72049 1.000 17.70401 ? 69  THR B CA  1 
ATOM   533  C C   . THR A  1 71 ? -12.81347 -12.71236 -45.22851 1.000 15.33983 ? 69  THR B C   1 
ATOM   534  O O   . THR A  1 71 ? -12.25268 -11.85922 -45.92301 1.000 18.73903 ? 69  THR B O   1 
ATOM   535  C CB  . THR A  1 71 ? -11.19507 -14.53062 -45.85409 1.000 22.61466 ? 69  THR B CB  1 
ATOM   536  O OG1 . THR A  1 71 ? -12.07071 -15.10304 -46.83346 1.000 20.92396 ? 69  THR B OG1 1 
ATOM   537  C CG2 . THR A  1 71 ? -10.26731 -15.61055 -45.31007 1.000 23.60427 ? 69  THR B CG2 1 
ATOM   538  N N   . THR A  1 72 ? -14.09565 -12.61567 -44.88531 1.000 14.29960 ? 70  THR B N   1 
ATOM   539  C CA  . THR A  1 72 ? -14.95903 -11.55877 -45.39941 1.000 15.20905 ? 70  THR B CA  1 
ATOM   540  C C   . THR A  1 72 ? -15.18809 -10.49871 -44.32875 1.000 13.37589 ? 70  THR B C   1 
ATOM   541  O O   . THR A  1 72 ? -15.75957 -10.78948 -43.27163 1.000 12.88376 ? 70  THR B O   1 
ATOM   542  C CB  . THR A  1 72 ? -16.29488 -12.13341 -45.86397 1.000 15.90698 ? 70  THR B CB  1 
ATOM   543  O OG1 . THR A  1 72 ? -16.05352 -13.13615 -46.85892 1.000 20.15140 ? 70  THR B OG1 1 
ATOM   544  C CG2 . THR A  1 72 ? -17.15973 -11.04099 -46.46761 1.000 16.42056 ? 70  THR B CG2 1 
ATOM   545  N N   . THR A  1 73 ? -14.76558 -9.27142  -44.61690 1.000 11.58010 ? 71  THR B N   1 
ATOM   546  C CA  . THR A  1 73 ? -14.95573 -8.13481  -43.72630 1.000 9.77018  ? 71  THR B CA  1 
ATOM   547  C C   . THR A  1 73 ? -16.02813 -7.23302  -44.32066 1.000 9.83234  ? 71  THR B C   1 
ATOM   548  O O   . THR A  1 73 ? -15.89117 -6.77648  -45.46409 1.000 12.65313 ? 71  THR B O   1 
ATOM   549  C CB  . THR A  1 73 ? -13.64737 -7.36313  -43.57032 1.000 10.42764 ? 71  THR B CB  1 
ATOM   550  O OG1 . THR A  1 73 ? -12.65085 -8.22125  -43.00237 1.000 11.43159 ? 71  THR B OG1 1 
ATOM   551  C CG2 . THR A  1 73 ? -13.85180 -6.14542  -42.68689 1.000 10.59634 ? 71  THR B CG2 1 
ATOM   552  N N   . THR A  1 74 ? -17.08525 -6.98169  -43.55122 1.000 9.68048  ? 72  THR B N   1 
ATOM   553  C CA  . THR A  1 74 ? -18.16788 -6.09485  -43.95115 1.000 10.34563 ? 72  THR B CA  1 
ATOM   554  C C   . THR A  1 74 ? -18.08037 -4.81287  -43.13860 1.000 9.08017  ? 72  THR B C   1 
ATOM   555  O O   . THR A  1 74 ? -17.96515 -4.86524  -41.91055 1.000 10.27871 ? 72  THR B O   1 
ATOM   556  C CB  . THR A  1 74 ? -19.52420 -6.76044  -43.70752 1.000 10.13933 ? 72  THR B CB  1 
ATOM   557  O OG1 . THR A  1 74 ? -19.57216 -8.00670  -44.41042 1.000 12.76294 ? 72  THR B OG1 1 
ATOM   558  C CG2 . THR A  1 74 ? -20.65129 -5.86502  -44.19511 1.000 13.78823 ? 72  THR B CG2 1 
ATOM   559  N N   . GLU A  1 75 ? -18.14357 -3.66817  -43.81910 1.000 8.55612  ? 73  GLU B N   1 
ATOM   560  C CA  . GLU A  1 75 ? -18.14836 -2.37112  -43.15988 1.000 8.19250  ? 73  GLU B CA  1 
ATOM   561  C C   . GLU A  1 75 ? -19.58305 -1.90903  -42.95037 1.000 8.91067  ? 73  GLU B C   1 
ATOM   562  O O   . GLU A  1 75 ? -20.39830 -1.93964  -43.87993 1.000 9.08926  ? 73  GLU B O   1 
ATOM   563  C CB  . GLU A  1 75 ? -17.41457 -1.34591  -44.02025 1.000 8.66451  ? 73  GLU B CB  1 
ATOM   564  C CG  . GLU A  1 75 ? -17.43403 0.08101   -43.48051 1.000 8.15505  ? 73  GLU B CG  1 
ATOM   565  C CD  . GLU A  1 75 ? -16.87733 1.07775   -44.48066 1.000 7.92462  ? 73  GLU B CD  1 
ATOM   566  O OE1 . GLU A  1 75 ? -17.30762 1.02330   -45.65462 1.000 8.70751  ? 73  GLU B OE1 1 
ATOM   567  O OE2 . GLU A  1 75 ? -16.02073 1.90189   -44.10127 1.000 8.19530  ? 73  GLU B OE2 1 
ATOM   568  N N   . TRP A  1 76 ? -19.87894 -1.47429  -41.73233 1.000 8.82532  ? 74  TRP B N   1 
ATOM   569  C CA  . TRP A  1 76 ? -21.17464 -0.92977  -41.35954 1.000 9.66525  ? 74  TRP B CA  1 
ATOM   570  C C   . TRP A  1 76 ? -20.98935 0.52775   -40.96553 1.000 9.58348  ? 74  TRP B C   1 
ATOM   571  O O   . TRP A  1 76 ? -20.03016 0.87436   -40.26567 1.000 9.61335  ? 74  TRP B O   1 
ATOM   572  C CB  . TRP A  1 76 ? -21.78683 -1.74035  -40.20925 1.000 9.78969  ? 74  TRP B CB  1 
ATOM   573  C CG  . TRP A  1 76 ? -22.11397 -3.13743  -40.62731 1.000 9.91808  ? 74  TRP B CG  1 
ATOM   574  C CD1 . TRP A  1 76 ? -21.38607 -4.26429  -40.39013 1.000 10.98816 ? 74  TRP B CD1 1 
ATOM   575  C CD2 . TRP A  1 76 ? -23.24887 -3.54416  -41.39113 1.000 10.17138 ? 74  TRP B CD2 1 
ATOM   576  N NE1 . TRP A  1 76 ? -22.00359 -5.35599  -40.95243 1.000 12.59908 ? 74  TRP B NE1 1 
ATOM   577  C CE2 . TRP A  1 76 ? -23.15171 -4.93799  -41.57445 1.000 12.39614 ? 74  TRP B CE2 1 
ATOM   578  C CE3 . TRP A  1 76 ? -24.34681 -2.86419  -41.93104 1.000 12.49051 ? 74  TRP B CE3 1 
ATOM   579  C CZ2 . TRP A  1 76 ? -24.11226 -5.66800  -42.28069 1.000 14.82913 ? 74  TRP B CZ2 1 
ATOM   580  C CZ3 . TRP A  1 76 ? -25.30127 -3.59133  -42.63114 1.000 14.87627 ? 74  TRP B CZ3 1 
ATOM   581  C CH2 . TRP A  1 76 ? -25.17563 -4.97726  -42.79695 1.000 16.28329 ? 74  TRP B CH2 1 
ATOM   582  N N   . CYS A  1 77 ? -21.90229 1.37981   -41.42762 1.000 9.44045  ? 75  CYS B N   1 
ATOM   583  C CA  . CYS A  1 77 ? -21.73735 2.82264   -41.36776 1.000 8.56056  ? 75  CYS B CA  1 
ATOM   584  C C   . CYS A  1 77 ? -22.89320 3.45636   -40.61715 1.000 10.10513 ? 75  CYS B C   1 
ATOM   585  O O   . CYS A  1 77 ? -24.05872 3.23746   -40.96480 1.000 11.61561 ? 75  CYS B O   1 
ATOM   586  C CB  . CYS A  1 77 ? -21.71052 3.41779   -42.77539 1.000 10.51809 ? 75  CYS B CB  1 
ATOM   587  S SG  . CYS A  1 77 ? -20.50847 2.65016   -43.86363 1.000 10.54535 ? 75  CYS B SG  1 
ATOM   588  N N   . TRP A  1 78 ? -22.56667 4.28215   -39.63400 1.000 9.96170  ? 76  TRP B N   1 
ATOM   589  C CA  . TRP A  1 78 ? -23.52889 5.16370   -38.98629 1.000 10.37444 ? 76  TRP B CA  1 
ATOM   590  C C   . TRP A  1 78 ? -23.23772 6.57378   -39.47625 1.000 13.18984 ? 76  TRP B C   1 
ATOM   591  O O   . TRP A  1 78 ? -22.18072 7.13146   -39.16951 1.000 12.82258 ? 76  TRP B O   1 
ATOM   592  C CB  . TRP A  1 78 ? -23.39807 5.09673   -37.46878 1.000 11.99868 ? 76  TRP B CB  1 
ATOM   593  C CG  . TRP A  1 78 ? -24.36902 6.01158   -36.79618 1.000 13.14474 ? 76  TRP B CG  1 
ATOM   594  C CD1 . TRP A  1 78 ? -24.19941 7.33831   -36.51754 1.000 14.91056 ? 76  TRP B CD1 1 
ATOM   595  C CD2 . TRP A  1 78 ? -25.67784 5.66934   -36.33598 1.000 12.86445 ? 76  TRP B CD2 1 
ATOM   596  N NE1 . TRP A  1 78 ? -25.32616 7.83938   -35.90025 1.000 15.68677 ? 76  TRP B NE1 1 
ATOM   597  C CE2 . TRP A  1 78 ? -26.24865 6.83341   -35.78218 1.000 14.99016 ? 76  TRP B CE2 1 
ATOM   598  C CE3 . TRP A  1 78 ? -26.42436 4.49001   -36.34088 1.000 13.01444 ? 76  TRP B CE3 1 
ATOM   599  C CZ2 . TRP A  1 78 ? -27.53523 6.84736   -35.23062 1.000 14.47138 ? 76  TRP B CZ2 1 
ATOM   600  C CZ3 . TRP A  1 78 ? -27.70131 4.50813   -35.79391 1.000 16.24078 ? 76  TRP B CZ3 1 
ATOM   601  C CH2 . TRP A  1 78 ? -28.23933 5.67604   -35.24880 1.000 15.12126 ? 76  TRP B CH2 1 
ATOM   602  N N   . ASP A  1 79 ? -24.17222 7.14130   -40.25236 1.000 15.10421 ? 77  ASP B N   1 
ATOM   603  C CA  . ASP A  1 79 ? -24.05634 8.50354   -40.76323 1.000 17.53036 ? 77  ASP B CA  1 
ATOM   604  C C   . ASP A  1 79 ? -25.31174 9.32679   -40.48534 1.000 29.05266 ? 77  ASP B C   1 
ATOM   605  O O   . ASP A  1 79 ? -25.49698 10.38753  -41.09213 1.000 29.88052 ? 77  ASP B O   1 
ATOM   606  C CB  . ASP A  1 79 ? -23.74667 8.50390   -42.26327 1.000 18.63302 ? 77  ASP B CB  1 
ATOM   607  C CG  . ASP A  1 79 ? -22.40959 7.86211   -42.58426 1.000 20.97721 ? 77  ASP B CG  1 
ATOM   608  O OD1 . ASP A  1 79 ? -21.38618 8.31792   -42.02866 1.000 14.47278 ? 77  ASP B OD1 1 
ATOM   609  O OD2 . ASP A  1 79 ? -22.38738 6.90517   -43.38940 1.000 22.74584 ? 77  ASP B OD2 1 
ATOM   610  N N   . GLY A  1 80 ? -26.18063 8.86022   -39.59421 1.000 25.68139 ? 78  GLY B N   1 
ATOM   611  C CA  . GLY A  1 80 ? -27.40324 9.56823   -39.27178 1.000 35.92795 ? 78  GLY B CA  1 
ATOM   612  C C   . GLY A  1 80 ? -28.66078 9.04363   -39.92993 1.000 40.65794 ? 78  GLY B C   1 
ATOM   613  O O   . GLY A  1 80 ? -29.68346 9.73935   -39.91320 1.000 38.72039 ? 78  GLY B O   1 
ATOM   614  N N   . ASN A  1 81 ? -28.61732 7.85281   -40.51975 1.000 35.31424 ? 79  ASN B N   1 
ATOM   615  C CA  . ASN A  1 81 ? -29.79557 7.20512   -41.08420 1.000 34.32657 ? 79  ASN B CA  1 
ATOM   616  C C   . ASN A  1 81 ? -29.78107 5.72340   -40.74038 1.000 17.20897 ? 79  ASN B C   1 
ATOM   617  O O   . ASN A  1 81 ? -30.04427 4.86547   -41.58976 1.000 29.16569 ? 79  ASN B O   1 
ATOM   618  C CB  . ASN A  1 81 ? -29.88414 7.42203   -42.59528 1.000 42.52830 ? 79  ASN B CB  1 
ATOM   619  C CG  . ASN A  1 81 ? -31.27429 7.83558   -43.04741 1.000 61.44112 ? 79  ASN B CG  1 
ATOM   620  O OD1 . ASN A  1 81 ? -32.26896 7.55737   -42.37586 1.000 62.12296 ? 79  ASN B OD1 1 
ATOM   621  N ND2 . ASN A  1 81 ? -31.34840 8.50428   -44.19407 1.000 59.45580 ? 79  ASN B ND2 1 
ATOM   622  N N   . GLY A  1 82 ? -29.45507 5.40608   -39.48634 1.000 27.65167 ? 80  GLY B N   1 
ATOM   623  C CA  . GLY A  1 82 ? -29.26387 4.02785   -39.08693 1.000 19.32196 ? 80  GLY B CA  1 
ATOM   624  C C   . GLY A  1 82 ? -27.96895 3.46105   -39.65721 1.000 16.06842 ? 80  GLY B C   1 
ATOM   625  O O   . GLY A  1 82 ? -27.15811 4.15619   -40.27179 1.000 19.32973 ? 80  GLY B O   1 
ATOM   626  N N   . TRP A  1 83 ? -27.78627 2.16405   -39.43948 1.000 12.92505 ? 81  TRP B N   1 
ATOM   627  C CA  . TRP A  1 83 ? -26.60024 1.47754   -39.93633 1.000 12.93534 ? 81  TRP B CA  1 
ATOM   628  C C   . TRP A  1 83 ? -26.80702 1.04532   -41.38304 1.000 12.85464 ? 81  TRP B C   1 
ATOM   629  O O   . TRP A  1 83 ? -27.84697 0.47486   -41.72938 1.000 15.76354 ? 81  TRP B O   1 
ATOM   630  C CB  . TRP A  1 83 ? -26.28507 0.26633   -39.06140 1.000 12.38779 ? 81  TRP B CB  1 
ATOM   631  C CG  . TRP A  1 83 ? -25.81740 0.63923   -37.68783 1.000 11.00566 ? 81  TRP B CG  1 
ATOM   632  C CD1 . TRP A  1 83 ? -26.57508 0.70588   -36.54672 1.000 11.12411 ? 81  TRP B CD1 1 
ATOM   633  C CD2 . TRP A  1 83 ? -24.48659 1.00405   -37.30676 1.000 10.22051 ? 81  TRP B CD2 1 
ATOM   634  N NE1 . TRP A  1 83 ? -25.79478 1.09231   -35.48458 1.000 11.51750 ? 81  TRP B NE1 1 
ATOM   635  C CE2 . TRP A  1 83 ? -24.50991 1.28513   -35.92316 1.000 9.74545  ? 81  TRP B CE2 1 
ATOM   636  C CE3 . TRP A  1 83 ? -23.27795 1.13034   -38.00135 1.000 10.82209 ? 81  TRP B CE3 1 
ATOM   637  C CZ2 . TRP A  1 83 ? -23.37361 1.66658   -35.22126 1.000 10.16669 ? 81  TRP B CZ2 1 
ATOM   638  C CZ3 . TRP A  1 83 ? -22.15003 1.50743   -37.30131 1.000 10.78481 ? 81  TRP B CZ3 1 
ATOM   639  C CH2 . TRP A  1 83 ? -22.20295 1.76970   -35.92624 1.000 9.97339  ? 81  TRP B CH2 1 
ATOM   640  N N   . THR A  1 84 ? -25.81644 1.32267   -42.23043 1.000 12.18709 ? 82  THR B N   1 
ATOM   641  C CA  . THR A  1 84 ? -25.88345 1.01506   -43.65208 1.000 13.36626 ? 82  THR B CA  1 
ATOM   642  C C   . THR A  1 84 ? -24.58480 0.34029   -44.06289 1.000 11.78426 ? 82  THR B C   1 
ATOM   643  O O   . THR A  1 84 ? -23.53153 0.59018   -43.47375 1.000 11.97703 ? 82  THR B O   1 
ATOM   644  C CB  . THR A  1 84 ? -26.09346 2.29910   -44.48242 1.000 16.21752 ? 82  THR B CB  1 
ATOM   645  O OG1 . THR A  1 84 ? -24.91909 3.11634   -44.42120 1.000 19.32063 ? 82  THR B OG1 1 
ATOM   646  C CG2 . THR A  1 84 ? -27.27426 3.10166   -43.94444 1.000 24.36868 ? 82  THR B CG2 1 
ATOM   647  N N   . LYS A  1 85 ? -24.65857 -0.51826  -45.07490 1.000 11.63393 ? 83  LYS B N   1 
ATOM   648  C CA  . LYS A  1 85 ? -23.45953 -1.19267  -45.55565 1.000 12.06191 ? 83  LYS B CA  1 
ATOM   649  C C   . LYS A  1 85 ? -22.54712 -0.20029  -46.26797 1.000 10.92623 ? 83  LYS B C   1 
ATOM   650  O O   . LYS A  1 85 ? -23.00113 0.61607   -47.07194 1.000 11.60412 ? 83  LYS B O   1 
ATOM   651  C CB  . LYS A  1 85 ? -23.83778 -2.32611  -46.50615 1.000 17.55265 ? 83  LYS B CB  1 
ATOM   652  C CG  . LYS A  1 85 ? -22.68435 -3.26446  -46.82155 1.000 24.44840 ? 83  LYS B CG  1 
ATOM   653  C CD  . LYS A  1 85 ? -23.18739 -4.60297  -47.33115 1.000 29.19114 ? 83  LYS B CD  1 
ATOM   654  C CE  . LYS A  1 85 ? -24.23934 -5.16925  -46.39066 1.000 30.64535 ? 83  LYS B CE  1 
ATOM   655  N NZ  . LYS A  1 85 ? -24.58438 -6.58291  -46.70703 1.000 40.70194 ? 83  LYS B NZ  1 
ATOM   656  N N   . GLY A  1 86 ? -21.25289 -0.26167  -45.96397 1.000 10.04981 ? 84  GLY B N   1 
ATOM   657  C CA  . GLY A  1 86 ? -20.29365 0.59343   -46.62836 1.000 11.13560 ? 84  GLY B CA  1 
ATOM   658  C C   . GLY A  1 86 ? -19.68846 -0.04915  -47.85877 1.000 10.37317 ? 84  GLY B C   1 
ATOM   659  O O   . GLY A  1 86 ? -19.90549 -1.22281  -48.14679 1.000 11.67646 ? 84  GLY B O   1 
ATOM   660  N N   . ALA A  1 87 ? -18.89307 0.74912   -48.56970 1.000 9.60465  ? 85  ALA B N   1 
ATOM   661  C CA  . ALA A  1 87 ? -18.23965 0.31378   -49.79547 1.000 9.21795  ? 85  ALA B CA  1 
ATOM   662  C C   . ALA A  1 87 ? -17.03178 -0.58577  -49.56121 1.000 8.91253  ? 85  ALA B C   1 
ATOM   663  O O   . ALA A  1 87 ? -16.55276 -1.19629  -50.52272 1.000 9.16993  ? 85  ALA B O   1 
ATOM   664  C CB  . ALA A  1 87 ? -17.80074 1.53257   -50.60565 1.000 9.90360  ? 85  ALA B CB  1 
ATOM   665  N N   . TYR A  1 88 ? -16.52552 -0.67485  -48.33109 1.000 8.71807  ? 86  TYR B N   1 
ATOM   666  C CA  . TYR A  1 88 ? -15.28460 -1.39848  -48.06630 1.000 7.50318  ? 86  TYR B CA  1 
ATOM   667  C C   . TYR A  1 88 ? -15.31373 -2.78835  -48.68119 1.000 7.52604  ? 86  TYR B C   1 
ATOM   668  O O   . TYR A  1 88 ? -16.27181 -3.54706  -48.50212 1.000 9.48780  ? 86  TYR B O   1 
ATOM   669  C CB  . TYR A  1 88 ? -15.08280 -1.54074  -46.55639 1.000 7.97915  ? 86  TYR B CB  1 
ATOM   670  C CG  . TYR A  1 88 ? -13.83640 -2.32119  -46.19942 1.000 8.11039  ? 86  TYR B CG  1 
ATOM   671  C CD1 . TYR A  1 88 ? -13.85833 -3.70486  -46.08127 1.000 8.92021  ? 86  TYR B CD1 1 
ATOM   672  C CD2 . TYR A  1 88 ? -12.63049 -1.66366  -46.00076 1.000 7.59275  ? 86  TYR B CD2 1 
ATOM   673  C CE1 . TYR A  1 88 ? -12.70156 -4.41712  -45.77396 1.000 8.66559  ? 86  TYR B CE1 1 
ATOM   674  C CE2 . TYR A  1 88 ? -11.47584 -2.35537  -45.68352 1.000 8.51595  ? 86  TYR B CE2 1 
ATOM   675  C CZ  . TYR A  1 88 ? -11.51610 -3.73089  -45.57478 1.000 8.16618  ? 86  TYR B CZ  1 
ATOM   676  O OH  . TYR A  1 88 ? -10.36458 -4.42150  -45.26358 1.000 9.94996  ? 86  TYR B OH  1 
ATOM   677  N N   . THR A  1 89 ? -14.23807 -3.12852  -49.37576 1.000 8.21334  ? 87  THR B N   1 
ATOM   678  C CA  . THR A  1 89 ? -13.94145 -4.50047  -49.73748 1.000 8.36526  ? 87  THR B CA  1 
ATOM   679  C C   . THR A  1 89 ? -12.47155 -4.74781  -49.44755 1.000 9.08450  ? 87  THR B C   1 
ATOM   680  O O   . THR A  1 89 ? -11.65758 -3.82154  -49.39864 1.000 9.20595  ? 87  THR B O   1 
ATOM   681  C CB  . THR A  1 89 ? -14.18211 -4.78569  -51.22627 1.000 10.54491 ? 87  THR B CB  1 
ATOM   682  O OG1 . THR A  1 89 ? -13.38597 -3.88920  -52.00867 1.000 10.44767 ? 87  THR B OG1 1 
ATOM   683  C CG2 . THR A  1 89 ? -15.65093 -4.61939  -51.58801 1.000 11.94628 ? 87  THR B CG2 1 
ATOM   684  N N   . ALA A  1 90 ? -12.13924 -6.02333  -49.29434 1.000 11.69416 ? 88  ALA B N   1 
ATOM   685  C CA  . ALA A  1 90 ? -10.75997 -6.46375  -49.19255 1.000 15.03942 ? 88  ALA B CA  1 
ATOM   686  C C   . ALA A  1 90 ? -10.66674 -7.82854  -49.85549 1.000 37.17716 ? 88  ALA B C   1 
ATOM   687  O O   . ALA A  1 90 ? -11.65632 -8.56122  -49.93638 1.000 40.64209 ? 88  ALA B O   1 
ATOM   688  C CB  . ALA A  1 90 ? -10.30666 -6.55075  -47.73428 1.000 22.88581 ? 88  ALA B CB  1 
ATOM   689  N N   . THR A  1 91 ? -9.47723  -8.16138  -50.34155 1.000 41.12208 ? 89  THR B N   1 
ATOM   690  C CA  . THR A  1 91 ? -9.23378  -9.43363  -51.01971 1.000 51.31228 ? 89  THR B CA  1 
ATOM   691  C C   . THR A  1 91 ? -8.43179  -10.31834 -50.06578 1.000 48.64270 ? 89  THR B C   1 
ATOM   692  O O   . THR A  1 91 ? -7.20160  -10.36308 -50.11773 1.000 57.73841 ? 89  THR B O   1 
ATOM   693  C CB  . THR A  1 91 ? -8.51021  -9.21188  -52.34936 1.000 51.17125 ? 89  THR B CB  1 
ATOM   694  O OG1 . THR A  1 91 ? -9.23839  -8.25872  -53.13471 1.000 42.82585 ? 89  THR B OG1 1 
ATOM   695  C CG2 . THR A  1 91 ? -8.40725  -10.51959 -53.12470 1.000 57.80271 ? 89  THR B CG2 1 
ATOM   696  N N   . ASN A  1 92 ? -9.14245  -11.02144 -49.19005 1.000 35.33353 ? 90  ASN B N   1 
ATOM   697  C CA  . ASN A  1 92 ? -8.50941  -11.87969 -48.19578 1.000 46.01690 ? 90  ASN B CA  1 
ATOM   698  C C   . ASN A  1 92 ? -8.57679  -13.34604 -48.62005 1.000 42.06537 ? 90  ASN B C   1 
ATOM   699  O O   . ASN A  1 92 ? -7.79667  -14.17863 -48.15226 1.000 39.84949 ? 90  ASN B O   1 
ATOM   700  C CB  . ASN A  1 92 ? -9.17576  -11.69400 -46.82823 1.000 42.77914 ? 90  ASN B CB  1 
ATOM   701  C CG  . ASN A  1 92 ? -8.98264  -10.29568 -46.26448 1.000 37.46298 ? 90  ASN B CG  1 
ATOM   702  O OD1 . ASN A  1 92 ? -7.89361  -9.72520  -46.34437 1.000 38.35513 ? 90  ASN B OD1 1 
ATOM   703  N ND2 . ASN A  1 92 ? -10.04476 -9.73640  -45.68935 1.000 29.20068 ? 90  ASN B ND2 1 
ATOM   704  N N   . MET B  1 1  ? -3.79666  -19.36721 -20.16044 1.000 25.54627 ? -1  MET C N   1 
ATOM   705  C CA  . MET B  1 1  ? -3.60085  -20.15996 -21.36935 1.000 16.91135 ? -1  MET C CA  1 
ATOM   706  C C   . MET B  1 1  ? -2.19729  -19.93182 -21.92661 1.000 15.07907 ? -1  MET C C   1 
ATOM   707  O O   . MET B  1 1  ? -1.45710  -19.08172 -21.43125 1.000 17.45372 ? -1  MET C O   1 
ATOM   708  C CB  . MET B  1 1  ? -4.65006  -19.79458 -22.41858 1.000 20.22553 ? -1  MET C CB  1 
ATOM   709  C CG  . MET B  1 1  ? -4.34257  -18.50255 -23.13978 1.000 35.63272 ? -1  MET C CG  1 
ATOM   710  S SD  . MET B  1 1  ? -5.80537  -17.51774 -23.49318 1.000 47.61013 ? -1  MET C SD  1 
ATOM   711  C CE  . MET B  1 1  ? -5.03839  -16.02476 -24.12182 1.000 41.49074 ? -1  MET C CE  1 
ATOM   712  N N   . LYS B  1 2  ? -1.84626  -20.70203 -22.95818 1.000 13.24789 ? 0   LYS C N   1 
ATOM   713  C CA  . LYS B  1 2  ? -0.51772  -20.63894 -23.55358 1.000 11.62687 ? 0   LYS C CA  1 
ATOM   714  C C   . LYS B  1 2  ? -0.16220  -19.20524 -23.93295 1.000 11.40970 ? 0   LYS C C   1 
ATOM   715  O O   . LYS B  1 2  ? -1.01121  -18.44269 -24.40346 1.000 12.65219 ? 0   LYS C O   1 
ATOM   716  C CB  . LYS B  1 2  ? -0.49699  -21.54150 -24.78798 1.000 12.43482 ? 0   LYS C CB  1 
ATOM   717  C CG  . LYS B  1 2  ? 0.82004   -21.59109 -25.53347 1.000 11.60422 ? 0   LYS C CG  1 
ATOM   718  C CD  . LYS B  1 2  ? 0.82538   -22.73325 -26.54836 1.000 11.93668 ? 0   LYS C CD  1 
ATOM   719  C CE  . LYS B  1 2  ? 2.10575   -22.76950 -27.36841 1.000 12.89158 ? 0   LYS C CE  1 
ATOM   720  N NZ  . LYS B  1 2  ? 2.20106   -21.59669 -28.27620 1.000 13.97197 ? 0   LYS C NZ  1 
ATOM   721  N N   . ALA B  1 3  ? 1.09788   -18.84077 -23.69865 1.000 10.77017 ? 1   ALA C N   1 
ATOM   722  C CA  . ALA B  1 3  ? 1.54480   -17.46526 -23.91049 1.000 13.15773 ? 1   ALA C CA  1 
ATOM   723  C C   . ALA B  1 3  ? 1.24962   -17.01151 -25.33406 1.000 11.88251 ? 1   ALA C C   1 
ATOM   724  O O   . ALA B  1 3  ? 1.57050   -17.71019 -26.29988 1.000 13.09963 ? 1   ALA C O   1 
ATOM   725  C CB  . ALA B  1 3  ? 3.04242   -17.35250 -23.62571 1.000 14.48780 ? 1   ALA C CB  1 
ATOM   726  N N   . SER B  1 4  ? 0.62972   -15.83412 -25.45619 1.000 14.89165 ? 2   SER C N   1 
ATOM   727  C CA  . SER B  1 4  ? 0.19004   -15.28945 -26.73913 1.000 14.26314 ? 2   SER C CA  1 
ATOM   728  C C   . SER B  1 4  ? -0.27443  -13.84689 -26.56250 1.000 13.48553 ? 2   SER C C   1 
ATOM   729  O O   . SER B  1 4  ? -1.15995  -13.57753 -25.74378 1.000 16.33254 ? 2   SER C O   1 
ATOM   730  C CB  . SER B  1 4  ? -0.95155  -16.13761 -27.30475 1.000 18.89704 ? 2   SER C CB  1 
ATOM   731  O OG  . SER B  1 4  ? -1.46951  -15.57417 -28.49827 1.000 32.12209 ? 2   SER C OG  1 
ATOM   732  N N   . VAL B  1 5  ? 0.28984   -12.91390 -27.33004 1.000 12.30035 ? 3   VAL C N   1 
ATOM   733  C CA  . VAL B  1 5  ? 0.09038   -11.48508 -27.10189 1.000 10.51738 ? 3   VAL C CA  1 
ATOM   734  C C   . VAL B  1 5  ? -1.01966  -10.95773 -27.99763 1.000 9.89658  ? 3   VAL C C   1 
ATOM   735  O O   . VAL B  1 5  ? -1.03626  -11.21355 -29.20808 1.000 11.94646 ? 3   VAL C O   1 
ATOM   736  C CB  . VAL B  1 5  ? 1.39925   -10.70353 -27.30975 1.000 14.01310 ? 3   VAL C CB  1 
ATOM   737  C CG1 . VAL B  1 5  ? 1.12020   -9.24774  -27.62330 1.000 15.62895 ? 3   VAL C CG1 1 
ATOM   738  C CG2 . VAL B  1 5  ? 2.28780   -10.83585 -26.07960 1.000 13.56407 ? 3   VAL C CG2 1 
ATOM   739  N N   . GLN B  1 6  ? -1.94265  -10.21538 -27.40216 1.000 9.18005  ? 4   GLN C N   1 
ATOM   740  C CA  . GLN B  1 6  ? -2.94909  -9.45697  -28.12801 1.000 9.33705  ? 4   GLN C CA  1 
ATOM   741  C C   . GLN B  1 6  ? -2.92866  -8.04385  -27.56851 1.000 8.48624  ? 4   GLN C C   1 
ATOM   742  O O   . GLN B  1 6  ? -2.79862  -7.86441  -26.35440 1.000 9.48127  ? 4   GLN C O   1 
ATOM   743  C CB  . GLN B  1 6  ? -4.32220  -10.09267 -27.92804 1.000 12.00087 ? 4   GLN C CB  1 
ATOM   744  C CG  . GLN B  1 6  ? -5.45460  -9.37606  -28.62483 1.000 15.49011 ? 4   GLN C CG  1 
ATOM   745  C CD  . GLN B  1 6  ? -6.18929  -8.41299  -27.71182 1.000 11.75462 ? 4   GLN C CD  1 
ATOM   746  O OE1 . GLN B  1 6  ? -6.43200  -8.70974  -26.54024 1.000 13.78073 ? 4   GLN C OE1 1 
ATOM   747  N NE2 . GLN B  1 6  ? -6.54319  -7.24707  -28.24389 1.000 15.11264 ? 4   GLN C NE2 1 
ATOM   748  N N   . THR B  1 7  ? -3.02832  -7.03336  -28.43888 1.000 7.51145  ? 5   THR C N   1 
ATOM   749  C CA  . THR B  1 7  ? -2.83760  -5.66144  -27.99183 1.000 7.07617  ? 5   THR C CA  1 
ATOM   750  C C   . THR B  1 7  ? -4.00878  -4.76537  -28.36381 1.000 6.62310  ? 5   THR C C   1 
ATOM   751  O O   . THR B  1 7  ? -4.82275  -5.07281  -29.24002 1.000 8.04455  ? 5   THR C O   1 
ATOM   752  C CB  . THR B  1 7  ? -1.55259  -5.01689  -28.55031 1.000 7.48372  ? 5   THR C CB  1 
ATOM   753  O OG1 . THR B  1 7  ? -1.70218  -4.74470  -29.95377 1.000 8.19671  ? 5   THR C OG1 1 
ATOM   754  C CG2 . THR B  1 7  ? -0.33126  -5.88859  -28.30067 1.000 9.75802  ? 5   THR C CG2 1 
ATOM   755  N N   . ALA B  1 8  ? -4.04346  -3.62465  -27.68721 1.000 7.43261  ? 6   ALA C N   1 
ATOM   756  C CA  . ALA B  1 8  ? -4.93143  -2.51902  -27.98736 1.000 6.94256  ? 6   ALA C CA  1 
ATOM   757  C C   . ALA B  1 8  ? -4.14598  -1.24616  -27.72668 1.000 6.60798  ? 6   ALA C C   1 
ATOM   758  O O   . ALA B  1 8  ? -3.26889  -1.21804  -26.85886 1.000 8.26143  ? 6   ALA C O   1 
ATOM   759  C CB  . ALA B  1 8  ? -6.18099  -2.55348  -27.10669 1.000 7.66095  ? 6   ALA C CB  1 
ATOM   760  N N   . ALA B  1 9  ? -4.44736  -0.19515  -28.48257 1.000 6.60492  ? 7   ALA C N   1 
ATOM   761  C CA  . ALA B  1 9  ? -3.65717  1.02488   -28.39703 1.000 6.78203  ? 7   ALA C CA  1 
ATOM   762  C C   . ALA B  1 9  ? -4.55813  2.25030   -28.44746 1.000 6.71094  ? 7   ALA C C   1 
ATOM   763  O O   . ALA B  1 9  ? -5.59049  2.25880   -29.12919 1.000 7.21555  ? 7   ALA C O   1 
ATOM   764  C CB  . ALA B  1 9  ? -2.62362  1.11732   -29.53203 1.000 8.75153  ? 7   ALA C CB  1 
ATOM   765  N N   . THR B  1 10 ? -4.13632  3.30287   -27.74618 1.000 6.63297  ? 8   THR C N   1 
ATOM   766  C CA  . THR B  1 10 ? -4.78877  4.59981   -27.83461 1.000 7.98462  ? 8   THR C CA  1 
ATOM   767  C C   . THR B  1 10 ? -3.71801  5.67742   -27.73504 1.000 6.71345  ? 8   THR C C   1 
ATOM   768  O O   . THR B  1 10 ? -2.59513  5.41861   -27.29886 1.000 8.11379  ? 8   THR C O   1 
ATOM   769  C CB  . THR B  1 10 ? -5.86097  4.77089   -26.73990 1.000 8.20628  ? 8   THR C CB  1 
ATOM   770  O OG1 . THR B  1 10 ? -6.66778  5.92598   -27.01316 1.000 9.26359  ? 8   THR C OG1 1 
ATOM   771  C CG2 . THR B  1 10 ? -5.23933  4.90107   -25.35810 1.000 9.64075  ? 8   THR C CG2 1 
ATOM   772  N N   . SER B  1 11 ? -4.07153  6.89994   -28.12861 1.000 7.19498  ? 9   SER C N   1 
ATOM   773  C CA  . SER B  1 11 ? -3.12263  8.00579   -28.09664 1.000 7.99177  ? 9   SER C CA  1 
ATOM   774  C C   . SER B  1 11 ? -3.89525  9.30724   -27.95432 1.000 7.90282  ? 9   SER C C   1 
ATOM   775  O O   . SER B  1 11 ? -5.09036  9.36660   -28.24576 1.000 8.22185  ? 9   SER C O   1 
ATOM   776  C CB  . SER B  1 11 ? -2.24260  8.03077   -29.34762 1.000 8.69179  ? 9   SER C CB  1 
ATOM   777  O OG  . SER B  1 11 ? -3.02459  8.18399   -30.51941 1.000 7.99774  ? 9   SER C OG  1 
ATOM   778  N N   . TRP B  1 12 ? -3.20298  10.35498  -27.49978 1.000 8.07387  ? 10  TRP C N   1 
ATOM   779  C CA  . TRP B  1 12 ? -3.83661  11.66123  -27.36805 1.000 9.12111  ? 10  TRP C CA  1 
ATOM   780  C C   . TRP B  1 12 ? -2.82133  12.78690  -27.51158 1.000 8.99888  ? 10  TRP C C   1 
ATOM   781  O O   . TRP B  1 12 ? -1.62926  12.62236  -27.24465 1.000 8.59531  ? 10  TRP C O   1 
ATOM   782  C CB  . TRP B  1 12 ? -4.61032  11.80344  -26.05245 1.000 9.78480  ? 10  TRP C CB  1 
ATOM   783  C CG  . TRP B  1 12 ? -3.80400  11.69274  -24.79026 1.000 8.97381  ? 10  TRP C CG  1 
ATOM   784  C CD1 . TRP B  1 12 ? -3.24288  12.71856  -24.07143 1.000 10.19284 ? 10  TRP C CD1 1 
ATOM   785  C CD2 . TRP B  1 12 ? -3.52423  10.49489  -24.05914 1.000 8.92805  ? 10  TRP C CD2 1 
ATOM   786  N NE1 . TRP B  1 12 ? -2.62101  12.22377  -22.95147 1.000 10.50628 ? 10  TRP C NE1 1 
ATOM   787  C CE2 . TRP B  1 12 ? -2.78142  10.86380  -22.91609 1.000 9.31622  ? 10  TRP C CE2 1 
ATOM   788  C CE3 . TRP B  1 12 ? -3.82505  9.14328   -24.26161 1.000 9.05371  ? 10  TRP C CE3 1 
ATOM   789  C CZ2 . TRP B  1 12 ? -2.32583  9.93151   -21.98747 1.000 9.98910  ? 10  TRP C CZ2 1 
ATOM   790  C CZ3 . TRP B  1 12 ? -3.37276  8.21662   -23.33703 1.000 10.33325 ? 10  TRP C CZ3 1 
ATOM   791  C CH2 . TRP B  1 12 ? -2.63487  8.61674   -22.20836 1.000 10.31661 ? 10  TRP C CH2 1 
ATOM   792  N N   . GLY B  1 13 ? -3.33080  13.94984  -27.91835 1.000 9.53302  ? 11  GLY C N   1 
ATOM   793  C CA  . GLY B  1 13 ? -2.50785  15.12906  -28.07741 1.000 11.46285 ? 11  GLY C CA  1 
ATOM   794  C C   . GLY B  1 13 ? -1.57549  15.01529  -29.26942 1.000 11.15405 ? 11  GLY C C   1 
ATOM   795  O O   . GLY B  1 13 ? -1.70953  14.14192  -30.12872 1.000 14.28412 ? 11  GLY C O   1 
ATOM   796  N N   . THR B  1 14 ? -0.61810  15.94374  -29.31612 1.000 11.81173 ? 12  THR C N   1 
ATOM   797  C CA  . THR B  1 14 ? 0.31754   16.01867  -30.42883 1.000 13.05897 ? 12  THR C CA  1 
ATOM   798  C C   . THR B  1 14 ? 1.72295   15.56385  -30.07751 1.000 13.68791 ? 12  THR C C   1 
ATOM   799  O O   . THR B  1 14 ? 2.55481   15.44933  -30.98290 1.000 16.74855 ? 12  THR C O   1 
ATOM   800  C CB  . THR B  1 14 ? 0.39440   17.44817  -30.98910 1.000 14.81744 ? 12  THR C CB  1 
ATOM   801  O OG1 . THR B  1 14 ? 0.81228   18.34117  -29.95024 1.000 16.23713 ? 12  THR C OG1 1 
ATOM   802  C CG2 . THR B  1 14 ? -0.95099  17.88671  -31.54114 1.000 17.07056 ? 12  THR C CG2 1 
ATOM   803  N N   . VAL B  1 15 ? 2.02341   15.32800  -28.79929 1.000 12.92391 ? 13  VAL C N   1 
ATOM   804  C CA  . VAL B  1 15 ? 3.35898   14.85239  -28.43433 1.000 12.44921 ? 13  VAL C CA  1 
ATOM   805  C C   . VAL B  1 15 ? 3.73830   13.57415  -29.17532 1.000 11.83011 ? 13  VAL C C   1 
ATOM   806  O O   . VAL B  1 15 ? 4.82633   13.53175  -29.77085 1.000 13.23221 ? 13  VAL C O   1 
ATOM   807  C CB  . VAL B  1 15 ? 3.50322   14.76463  -26.90325 1.000 13.41090 ? 13  VAL C CB  1 
ATOM   808  C CG1 . VAL B  1 15 ? 4.84292   14.14524  -26.53934 1.000 15.21033 ? 13  VAL C CG1 1 
ATOM   809  C CG2 . VAL B  1 15 ? 3.34487   16.14235  -26.26606 1.000 14.47773 ? 13  VAL C CG2 1 
ATOM   810  N N   . PRO B  1 16 ? 2.91640   12.51628  -29.18839 1.000 9.94126  ? 14  PRO C N   1 
ATOM   811  C CA  . PRO B  1 16 ? 1.67024   12.30841  -28.45843 1.000 9.38567  ? 14  PRO C CA  1 
ATOM   812  C C   . PRO B  1 16 ? 1.98760   11.54890  -27.18751 1.000 8.82587  ? 14  PRO C C   1 
ATOM   813  O O   . PRO B  1 16 ? 3.13388   11.16231  -26.94394 1.000 9.56248  ? 14  PRO C O   1 
ATOM   814  C CB  . PRO B  1 16 ? 0.90489   11.38044  -29.39916 1.000 10.46954 ? 14  PRO C CB  1 
ATOM   815  C CG  . PRO B  1 16 ? 1.99175   10.45343  -29.86968 1.000 10.03143 ? 14  PRO C CG  1 
ATOM   816  C CD  . PRO B  1 16 ? 3.21091   11.35442  -30.04825 1.000 10.20741 ? 14  PRO C CD  1 
ATOM   817  N N   . SER B  1 17 ? 0.96798   11.31220  -26.37408 1.000 8.29351  ? 15  SER C N   1 
ATOM   818  C CA  . SER B  1 17 ? 1.00615   10.20917  -25.43638 1.000 8.28955  ? 15  SER C CA  1 
ATOM   819  C C   . SER B  1 17 ? 0.38282   9.00415   -26.11717 1.000 7.74629  ? 15  SER C C   1 
ATOM   820  O O   . SER B  1 17 ? -0.61661  9.13094   -26.82405 1.000 8.93844  ? 15  SER C O   1 
ATOM   821  C CB  . SER B  1 17 ? 0.22495   10.54268  -24.17311 1.000 8.81060  ? 15  SER C CB  1 
ATOM   822  O OG  . SER B  1 17 ? 0.94878   11.42834  -23.33796 1.000 11.16009 ? 15  SER C OG  1 
ATOM   823  N N   . ILE B  1 18 ? 0.98987   7.84379   -25.91655 1.000 7.74027  ? 16  ILE C N   1 
ATOM   824  C CA  . ILE B  1 18 ? 0.48445   6.57715   -26.42511 1.000 7.01440  ? 16  ILE C CA  1 
ATOM   825  C C   . ILE B  1 18 ? 0.41279   5.61086   -25.25743 1.000 6.33325  ? 16  ILE C C   1 
ATOM   826  O O   . ILE B  1 18 ? 1.30393   5.59521   -24.39996 1.000 7.59141  ? 16  ILE C O   1 
ATOM   827  C CB  . ILE B  1 18 ? 1.38864   5.97302   -27.51997 1.000 7.60623  ? 16  ILE C CB  1 
ATOM   828  C CG1 . ILE B  1 18 ? 1.78099   6.99891   -28.58266 1.000 8.62640  ? 16  ILE C CG1 1 
ATOM   829  C CG2 . ILE B  1 18 ? 0.71101   4.76566   -28.14516 1.000 8.53466  ? 16  ILE C CG2 1 
ATOM   830  C CD1 . ILE B  1 18 ? 2.85097   6.48183   -29.53104 1.000 9.03644  ? 16  ILE C CD1 1 
ATOM   831  N N   . ARG B  1 19 ? -0.63499  4.79390   -25.23201 1.000 6.95506  ? 17  ARG C N   1 
ATOM   832  C CA  . ARG B  1 19 ? -0.72851  3.68917   -24.28776 1.000 7.05671  ? 17  ARG C CA  1 
ATOM   833  C C   . ARG B  1 19 ? -1.04133  2.42106   -25.06784 1.000 7.10334  ? 17  ARG C C   1 
ATOM   834  O O   . ARG B  1 19 ? -1.97174  2.40535   -25.88644 1.000 7.83029  ? 17  ARG C O   1 
ATOM   835  C CB  . ARG B  1 19 ? -1.81178  3.93835   -23.23332 1.000 7.72416  ? 17  ARG C CB  1 
ATOM   836  C CG  . ARG B  1 19 ? -1.60142  5.17860   -22.37715 1.000 7.65506  ? 17  ARG C CG  1 
ATOM   837  C CD  . ARG B  1 19 ? -0.36976  5.04258   -21.48118 1.000 7.75850  ? 17  ARG C CD  1 
ATOM   838  N NE  . ARG B  1 19 ? -0.16586  6.19419   -20.60551 1.000 8.09495  ? 17  ARG C NE  1 
ATOM   839  C CZ  . ARG B  1 19 ? 0.55024   7.26949   -20.91294 1.000 8.87457  ? 17  ARG C CZ  1 
ATOM   840  N NH1 . ARG B  1 19 ? 1.17062   7.38136   -22.07852 1.000 8.40220  ? 17  ARG C NH1 1 
ATOM   841  N NH2 . ARG B  1 19 ? 0.65526   8.25882   -20.02815 1.000 9.47894  ? 17  ARG C NH2 1 
ATOM   842  N N   . VAL B  1 20 ? -0.24566  1.37760   -24.84015 1.000 6.42578  ? 18  VAL C N   1 
ATOM   843  C CA  . VAL B  1 20 ? -0.41144  0.08301   -25.49403 1.000 6.95397  ? 18  VAL C CA  1 
ATOM   844  C C   . VAL B  1 20 ? -0.65910  -0.95694  -24.41518 1.000 5.97803  ? 18  VAL C C   1 
ATOM   845  O O   . VAL B  1 20 ? 0.17305   -1.12886  -23.50923 1.000 7.00456  ? 18  VAL C O   1 
ATOM   846  C CB  . VAL B  1 20 ? 0.81260   -0.29943  -26.34012 1.000 7.43361  ? 18  VAL C CB  1 
ATOM   847  C CG1 . VAL B  1 20 ? 0.58618   -1.64186  -27.01589 1.000 8.70537  ? 18  VAL C CG1 1 
ATOM   848  C CG2 . VAL B  1 20 ? 1.10208   0.76943   -27.38028 1.000 8.46551  ? 18  VAL C CG2 1 
ATOM   849  N N   . TYR B  1 21 ? -1.79401  -1.64885  -24.51500 1.000 6.97537  ? 19  TYR C N   1 
ATOM   850  C CA  . TYR B  1 21 ? -2.20962  -2.66885  -23.55883 1.000 7.48884  ? 19  TYR C CA  1 
ATOM   851  C C   . TYR B  1 21 ? -1.97467  -4.03162  -24.18684 1.000 7.05523  ? 19  TYR C C   1 
ATOM   852  O O   . TYR B  1 21 ? -2.33989  -4.25228  -25.34532 1.000 8.28362  ? 19  TYR C O   1 
ATOM   853  C CB  . TYR B  1 21 ? -3.69372  -2.48725  -23.18403 1.000 7.88334  ? 19  TYR C CB  1 
ATOM   854  C CG  . TYR B  1 21 ? -3.87977  -1.12603  -22.57631 1.000 7.33152  ? 19  TYR C CG  1 
ATOM   855  C CD1 . TYR B  1 21 ? -4.11729  -0.01431  -23.38004 1.000 7.33198  ? 19  TYR C CD1 1 
ATOM   856  C CD2 . TYR B  1 21 ? -3.70853  -0.92530  -21.21225 1.000 8.24678  ? 19  TYR C CD2 1 
ATOM   857  C CE1 . TYR B  1 21 ? -4.19821  1.24312   -22.84816 1.000 7.03577  ? 19  TYR C CE1 1 
ATOM   858  C CE2 . TYR B  1 21 ? -3.79925  0.33328   -20.66806 1.000 7.45824  ? 19  TYR C CE2 1 
ATOM   859  C CZ  . TYR B  1 21 ? -4.03124  1.41472   -21.49314 1.000 7.43170  ? 19  TYR C CZ  1 
ATOM   860  O OH  . TYR B  1 21 ? -4.09416  2.68491   -20.98861 1.000 8.09005  ? 19  TYR C OH  1 
ATOM   861  N N   . THR B  1 22 ? -1.37992  -4.94141  -23.42375 1.000 7.79692  ? 20  THR C N   1 
ATOM   862  C CA  . THR B  1 22 ? -1.05209  -6.27555  -23.90597 1.000 7.80201  ? 20  THR C CA  1 
ATOM   863  C C   . THR B  1 22 ? -1.68288  -7.31274  -22.99474 1.000 8.07700  ? 20  THR C C   1 
ATOM   864  O O   . THR B  1 22 ? -1.38786  -7.34121  -21.79431 1.000 9.01498  ? 20  THR C O   1 
ATOM   865  C CB  . THR B  1 22 ? 0.46331   -6.47690  -23.90988 1.000 8.61499  ? 20  THR C CB  1 
ATOM   866  O OG1 . THR B  1 22 ? 1.06093   -5.59599  -24.86605 1.000 9.33520  ? 20  THR C OG1 1 
ATOM   867  C CG2 . THR B  1 22 ? 0.81836   -7.90824  -24.26680 1.000 10.54036 ? 20  THR C CG2 1 
ATOM   868  N N   . ALA B  1 23 ? -2.53042  -8.16810  -23.56714 1.000 8.30524  ? 21  ALA C N   1 
ATOM   869  C CA  . ALA B  1 23 ? -3.04410  -9.34064  -22.87186 1.000 8.70371  ? 21  ALA C CA  1 
ATOM   870  C C   . ALA B  1 23 ? -2.14555  -10.52956 -23.18162 1.000 8.43410  ? 21  ALA C C   1 
ATOM   871  O O   . ALA B  1 23 ? -1.92020  -10.86062 -24.34803 1.000 10.36019 ? 21  ALA C O   1 
ATOM   872  C CB  . ALA B  1 23 ? -4.47856  -9.64791  -23.30164 1.000 10.64098 ? 21  ALA C CB  1 
ATOM   873  N N   . ASN B  1 24 ? -1.64870  -11.17902 -22.13537 1.000 9.67670  ? 22  ASN C N   1 
ATOM   874  C CA  . ASN B  1 24 ? -0.77049  -12.33284 -22.28426 1.000 9.88591  ? 22  ASN C CA  1 
ATOM   875  C C   . ASN B  1 24 ? -0.83069  -13.12508 -20.98636 1.000 10.22104 ? 22  ASN C C   1 
ATOM   876  O O   . ASN B  1 24 ? -0.71362  -12.54232 -19.90502 1.000 11.81194 ? 22  ASN C O   1 
ATOM   877  C CB  . ASN B  1 24 ? 0.66627   -11.86203 -22.54789 1.000 10.35210 ? 22  ASN C CB  1 
ATOM   878  C CG  . ASN B  1 24 ? 1.61665   -12.99999 -22.84316 1.000 13.42703 ? 22  ASN C CG  1 
ATOM   879  O OD1 . ASN B  1 24 ? 1.19846   -14.10527 -23.19566 1.000 18.15736 ? 22  ASN C OD1 1 
ATOM   880  N ND2 . ASN B  1 24 ? 2.91374   -12.72721 -22.72639 1.000 14.20156 ? 22  ASN C ND2 1 
ATOM   881  N N   . ASN B  1 25 ? -1.02785  -14.43953 -21.08677 1.000 12.25393 ? 23  ASN C N   1 
ATOM   882  C CA  . ASN B  1 25 ? -1.03138  -15.30532 -19.90188 1.000 16.13047 ? 23  ASN C CA  1 
ATOM   883  C C   . ASN B  1 25 ? -2.07199  -14.87287 -18.86586 1.000 14.93201 ? 23  ASN C C   1 
ATOM   884  O O   . ASN B  1 25 ? -1.83990  -14.97938 -17.65823 1.000 16.01010 ? 23  ASN C O   1 
ATOM   885  C CB  . ASN B  1 25 ? 0.35730   -15.38702 -19.25389 1.000 18.26193 ? 23  ASN C CB  1 
ATOM   886  C CG  . ASN B  1 25 ? 1.43455   -15.84625 -20.22036 1.000 29.09002 ? 23  ASN C CG  1 
ATOM   887  O OD1 . ASN B  1 25 ? 1.29940   -16.88445 -20.86449 1.000 27.04292 ? 23  ASN C OD1 1 
ATOM   888  N ND2 . ASN B  1 25 ? 2.51534   -15.07383 -20.32036 1.000 28.52296 ? 23  ASN C ND2 1 
ATOM   889  N N   . GLY B  1 26 ? -3.21052  -14.35314 -19.31586 1.000 13.17127 ? 24  GLY C N   1 
ATOM   890  C CA  . GLY B  1 26 ? -4.27549  -13.97583 -18.40893 1.000 14.43134 ? 24  GLY C CA  1 
ATOM   891  C C   . GLY B  1 26 ? -4.12316  -12.63128 -17.73562 1.000 12.23897 ? 24  GLY C C   1 
ATOM   892  O O   . GLY B  1 26 ? -4.93163  -12.30202 -16.85807 1.000 12.29320 ? 24  GLY C O   1 
ATOM   893  N N   . LYS B  1 27 ? -3.12029  -11.84235 -18.10861 1.000 10.75378 ? 25  LYS C N   1 
ATOM   894  C CA  . LYS B  1 27 ? -2.90456  -10.53634 -17.50676 1.000 12.83920 ? 25  LYS C CA  1 
ATOM   895  C C   . LYS B  1 27 ? -2.76417  -9.49617  -18.60096 1.000 9.08493  ? 25  LYS C C   1 
ATOM   896  O O   . LYS B  1 27 ? -2.14137  -9.74486  -19.63724 1.000 10.51759 ? 25  LYS C O   1 
ATOM   897  C CB  . LYS B  1 27 ? -1.63982  -10.51167 -16.63652 1.000 14.96071 ? 25  LYS C CB  1 
ATOM   898  C CG  . LYS B  1 27 ? -1.68779  -11.40624 -15.40397 1.000 18.95773 ? 25  LYS C CG  1 
ATOM   899  C CD  . LYS B  1 27 ? -2.64940  -10.86819 -14.35274 1.000 25.63407 ? 25  LYS C CD  1 
ATOM   900  C CE  . LYS B  1 27 ? -1.95238  -10.66978 -13.00941 1.000 44.85810 ? 25  LYS C CE  1 
ATOM   901  N NZ  . LYS B  1 27 ? -1.03361  -9.49352  -13.01131 1.000 39.82641 ? 25  LYS C NZ  1 
ATOM   902  N N   . ILE B  1 28 ? -3.32890  -8.32351  -18.35222 1.000 9.65812  ? 26  ILE C N   1 
ATOM   903  C CA  . ILE B  1 28 ? -3.17863  -7.17652  -19.23423 1.000 8.49632  ? 26  ILE C CA  1 
ATOM   904  C C   . ILE B  1 28 ? -2.26724  -6.17650  -18.54338 1.000 8.94337  ? 26  ILE C C   1 
ATOM   905  O O   . ILE B  1 28 ? -2.53609  -5.76227  -17.40634 1.000 10.43887 ? 26  ILE C O   1 
ATOM   906  C CB  . ILE B  1 28 ? -4.52835  -6.53268  -19.56829 1.000 10.00038 ? 26  ILE C CB  1 
ATOM   907  C CG1 . ILE B  1 28 ? -5.43650  -7.52600  -20.28901 1.000 10.66704 ? 26  ILE C CG1 1 
ATOM   908  C CG2 . ILE B  1 28 ? -4.31290  -5.29742  -20.42369 1.000 10.02989 ? 26  ILE C CG2 1 
ATOM   909  C CD1 . ILE B  1 28 ? -6.88603  -7.10095  -20.31869 1.000 11.38996 ? 26  ILE C CD1 1 
ATOM   910  N N   . THR B  1 29 ? -1.19624  -5.78903  -19.22670 1.000 8.32815  ? 27  THR C N   1 
ATOM   911  C CA  . THR B  1 29 ? -0.25784  -4.79094  -18.75135 1.000 9.01050  ? 27  THR C CA  1 
ATOM   912  C C   . THR B  1 29 ? -0.17224  -3.65074  -19.76263 1.000 7.92172  ? 27  THR C C   1 
ATOM   913  O O   . THR B  1 29 ? -0.74341  -3.71189  -20.85987 1.000 9.04200  ? 27  THR C O   1 
ATOM   914  C CB  . THR B  1 29 ? 1.11879   -5.41086  -18.50240 1.000 9.57139  ? 27  THR C CB  1 
ATOM   915  O OG1 . THR B  1 29 ? 1.57012   -6.05381  -19.69860 1.000 11.51733 ? 27  THR C OG1 1 
ATOM   916  C CG2 . THR B  1 29 ? 1.04264   -6.44212  -17.39237 1.000 11.63116 ? 27  THR C CG2 1 
ATOM   917  N N   . GLU B  1 30 ? 0.55826   -2.60006  -19.39338 1.000 7.91701  ? 28  GLU C N   1 
ATOM   918  C CA  . GLU B  1 30 ? 0.49069   -1.33217  -20.10253 1.000 7.79278  ? 28  GLU C CA  1 
ATOM   919  C C   . GLU B  1 30 ? 1.89151   -0.77673  -20.30643 1.000 6.83147  ? 28  GLU C C   1 
ATOM   920  O O   . GLU B  1 30 ? 2.68635   -0.71890  -19.36022 1.000 8.07760  ? 28  GLU C O   1 
ATOM   921  C CB  . GLU B  1 30 ? -0.33124  -0.34003  -19.26705 1.000 8.76958  ? 28  GLU C CB  1 
ATOM   922  C CG  . GLU B  1 30 ? -0.50169  1.04075   -19.85603 1.000 8.74382  ? 28  GLU C CG  1 
ATOM   923  C CD  . GLU B  1 30 ? -1.11822  2.00369   -18.85218 1.000 7.70039  ? 28  GLU C CD  1 
ATOM   924  O OE1 . GLU B  1 30 ? -0.72010  1.95063   -17.66503 1.000 8.82033  ? 28  GLU C OE1 1 
ATOM   925  O OE2 . GLU B  1 30 ? -1.98870  2.81673   -19.23573 1.000 8.34888  ? 28  GLU C OE2 1 
ATOM   926  N N   . ARG B  1 31 ? 2.17287   -0.32940  -21.52503 1.000 7.37084  ? 29  ARG C N   1 
ATOM   927  C CA  . ARG B  1 31 ? 3.38682   0.40007   -21.84302 1.000 7.91791  ? 29  ARG C CA  1 
ATOM   928  C C   . ARG B  1 31 ? 2.99699   1.79491   -22.30301 1.000 7.13779  ? 29  ARG C C   1 
ATOM   929  O O   . ARG B  1 31 ? 1.97558   1.97274   -22.98454 1.000 8.04116  ? 29  ARG C O   1 
ATOM   930  C CB  . ARG B  1 31 ? 4.18272   -0.33966  -22.92079 1.000 8.75793  ? 29  ARG C CB  1 
ATOM   931  C CG  . ARG B  1 31 ? 4.73092   -1.68574  -22.43729 1.000 10.04922 ? 29  ARG C CG  1 
ATOM   932  C CD  . ARG B  1 31 ? 5.95905   -1.52226  -21.54561 1.000 10.60971 ? 29  ARG C CD  1 
ATOM   933  N NE  . ARG B  1 31 ? 7.16713   -1.28944  -22.33160 1.000 9.67607  ? 29  ARG C NE  1 
ATOM   934  C CZ  . ARG B  1 31 ? 8.32829   -0.90342  -21.82268 1.000 10.58905 ? 29  ARG C CZ  1 
ATOM   935  N NH1 . ARG B  1 31 ? 8.46691   -0.63835  -20.53272 1.000 11.86378 ? 29  ARG C NH1 1 
ATOM   936  N NH2 . ARG B  1 31 ? 9.37532   -0.76589  -22.63298 1.000 11.79633 ? 29  ARG C NH2 1 
ATOM   937  N N   . CYS B  1 32 ? 3.81248   2.77904   -21.93281 1.000 7.80964  ? 30  CYS C N   1 
ATOM   938  C CA  . CYS B  1 32 ? 3.46318   4.18114   -22.06153 1.000 7.43690  ? 30  CYS C CA  1 
ATOM   939  C C   . CYS B  1 32 ? 4.55240   4.92937   -22.80310 1.000 8.21609  ? 30  CYS C C   1 
ATOM   940  O O   . CYS B  1 32 ? 5.74546   4.72728   -22.54658 1.000 8.69541  ? 30  CYS C O   1 
ATOM   941  C CB  . CYS B  1 32 ? 3.34244   4.83957   -20.68524 1.000 7.94616  ? 30  CYS C CB  1 
ATOM   942  S SG  . CYS B  1 32 ? 2.28190   3.96818   -19.52834 1.000 9.02486  ? 30  CYS C SG  1 
ATOM   943  N N   . TRP B  1 33 ? 4.12603   5.84126   -23.67128 1.000 7.76123  ? 31  TRP C N   1 
ATOM   944  C CA  . TRP B  1 33 ? 5.00894   6.78084   -24.34233 1.000 8.20391  ? 31  TRP C CA  1 
ATOM   945  C C   . TRP B  1 33 ? 4.46308   8.17190   -24.08970 1.000 8.55098  ? 31  TRP C C   1 
ATOM   946  O O   . TRP B  1 33 ? 3.28457   8.42646   -24.35558 1.000 8.75100  ? 31  TRP C O   1 
ATOM   947  C CB  . TRP B  1 33 ? 5.00644   6.51562   -25.85165 1.000 8.10592  ? 31  TRP C CB  1 
ATOM   948  C CG  . TRP B  1 33 ? 5.79735   7.50086   -26.66843 1.000 9.35852  ? 31  TRP C CG  1 
ATOM   949  C CD1 . TRP B  1 33 ? 5.34903   8.65263   -27.25499 1.000 9.24239  ? 31  TRP C CD1 1 
ATOM   950  C CD2 . TRP B  1 33 ? 7.16923   7.38256   -27.01861 1.000 8.78423  ? 31  TRP C CD2 1 
ATOM   951  N NE1 . TRP B  1 33 ? 6.37725   9.26459   -27.94144 1.000 9.89187  ? 31  TRP C NE1 1 
ATOM   952  C CE2 . TRP B  1 33 ? 7.50737   8.50314   -27.79934 1.000 9.66215  ? 31  TRP C CE2 1 
ATOM   953  C CE3 . TRP B  1 33 ? 8.14694   6.43317   -26.74633 1.000 8.41058  ? 31  TRP C CE3 1 
ATOM   954  C CZ2 . TRP B  1 33 ? 8.78871   8.69221   -28.31323 1.000 10.95270 ? 31  TRP C CZ2 1 
ATOM   955  C CZ3 . TRP B  1 33 ? 9.41240   6.62246   -27.25373 1.000 10.27716 ? 31  TRP C CZ3 1 
ATOM   956  C CH2 . TRP B  1 33 ? 9.72375   7.74458   -28.02445 1.000 10.53287 ? 31  TRP C CH2 1 
ATOM   957  N N   . ASP B  1 34 ? 5.31251   9.07204   -23.57991 1.000 9.26272  ? 32  ASP C N   1 
ATOM   958  C CA  . ASP B  1 34 ? 4.95845   10.47704  -23.40978 1.000 10.53964 ? 32  ASP C CA  1 
ATOM   959  C C   . ASP B  1 34 ? 5.97275   11.37443  -24.10883 1.000 11.28939 ? 32  ASP C C   1 
ATOM   960  O O   . ASP B  1 34 ? 6.23217   12.49543  -23.66340 1.000 15.53025 ? 32  ASP C O   1 
ATOM   961  C CB  . ASP B  1 34 ? 4.84596   10.87618  -21.93516 1.000 13.09538 ? 32  ASP C CB  1 
ATOM   962  C CG  . ASP B  1 34 ? 3.73304   10.14859  -21.18720 1.000 14.15047 ? 32  ASP C CG  1 
ATOM   963  O OD1 . ASP B  1 34 ? 2.61675   9.97053   -21.71929 1.000 11.84494 ? 32  ASP C OD1 1 
ATOM   964  O OD2 . ASP B  1 34 ? 3.98269   9.78186   -20.02075 1.000 21.41707 ? 32  ASP C OD2 1 
ATOM   965  N N   . GLY B  1 35 ? 6.57888   10.88558  -25.18358 1.000 10.29622 ? 33  GLY C N   1 
ATOM   966  C CA  . GLY B  1 35 ? 7.47941   11.68757  -25.98448 1.000 10.83279 ? 33  GLY C CA  1 
ATOM   967  C C   . GLY B  1 35 ? 8.95519   11.50221  -25.70824 1.000 10.69393 ? 33  GLY C C   1 
ATOM   968  O O   . GLY B  1 35 ? 9.77657   12.09782  -26.41897 1.000 12.28446 ? 33  GLY C O   1 
ATOM   969  N N   . LYS B  1 36 ? 9.32282   10.68468  -24.72244 1.000 9.30434  ? 34  LYS C N   1 
ATOM   970  C CA  . LYS B  1 36 ? 10.70764  10.60633  -24.27762 1.000 9.69303  ? 34  LYS C CA  1 
ATOM   971  C C   . LYS B  1 36 ? 11.11699  9.18372   -23.91601 1.000 11.81621 ? 34  LYS C C   1 
ATOM   972  O O   . LYS B  1 36 ? 12.01186  8.99009   -23.08588 1.000 21.39460 ? 34  LYS C O   1 
ATOM   973  C CB  . LYS B  1 36 ? 10.94771  11.51993  -23.07126 1.000 15.32478 ? 34  LYS C CB  1 
ATOM   974  C CG  . LYS B  1 36 ? 10.69548  12.99613  -23.33319 1.000 18.49770 ? 34  LYS C CG  1 
ATOM   975  C CD  . LYS B  1 36 ? 11.10862  13.84251  -22.14014 1.000 26.19347 ? 34  LYS C CD  1 
ATOM   976  C CE  . LYS B  1 36 ? 10.81245  15.31400  -22.37787 1.000 31.09021 ? 34  LYS C CE  1 
ATOM   977  N NZ  . LYS B  1 36 ? 11.51070  15.82488  -23.58647 1.000 30.67111 ? 34  LYS C NZ  1 
ATOM   978  N N   . GLY B  1 37 ? 10.48698  8.17768   -24.51424 1.000 10.43961 ? 35  GLY C N   1 
ATOM   979  C CA  . GLY B  1 37 ? 10.84138  6.80484   -24.21310 1.000 11.02226 ? 35  GLY C CA  1 
ATOM   980  C C   . GLY B  1 37 ? 9.67348   5.99482   -23.68537 1.000 10.16693 ? 35  GLY C C   1 
ATOM   981  O O   . GLY B  1 37 ? 8.73455   6.55139   -23.10544 1.000 10.97809 ? 35  GLY C O   1 
ATOM   982  N N   . TRP B  1 38 ? 9.72472   4.68060   -23.87000 1.000 9.09333  ? 36  TRP C N   1 
ATOM   983  C CA  . TRP B  1 38 ? 8.68132   3.79205   -23.37671 1.000 9.40527  ? 36  TRP C CA  1 
ATOM   984  C C   . TRP B  1 38 ? 8.96002   3.40280   -21.93295 1.000 9.41545  ? 36  TRP C C   1 
ATOM   985  O O   . TRP B  1 38 ? 10.10878  3.16930   -21.54776 1.000 11.25739 ? 36  TRP C O   1 
ATOM   986  C CB  . TRP B  1 38 ? 8.59852   2.53000   -24.23631 1.000 9.18546  ? 36  TRP C CB  1 
ATOM   987  C CG  . TRP B  1 38 ? 8.02435   2.79808   -25.57914 1.000 8.39632  ? 36  TRP C CG  1 
ATOM   988  C CD1 . TRP B  1 38 ? 8.70956   3.07176   -26.72141 1.000 9.33294  ? 36  TRP C CD1 1 
ATOM   989  C CD2 . TRP B  1 38 ? 6.63341   2.85834   -25.91628 1.000 7.50575  ? 36  TRP C CD2 1 
ATOM   990  N NE1 . TRP B  1 38 ? 7.83194   3.28581   -27.75447 1.000 8.77442  ? 36  TRP C NE1 1 
ATOM   991  C CE2 . TRP B  1 38 ? 6.55107   3.16720   -27.28252 1.000 7.58417  ? 36  TRP C CE2 1 
ATOM   992  C CE3 . TRP B  1 38 ? 5.44811   2.68095   -25.19049 1.000 8.25106  ? 36  TRP C CE3 1 
ATOM   993  C CZ2 . TRP B  1 38 ? 5.33671   3.29604   -27.94672 1.000 7.38756  ? 36  TRP C CZ2 1 
ATOM   994  C CZ3 . TRP B  1 38 ? 4.23650   2.80827   -25.85454 1.000 8.17516  ? 36  TRP C CZ3 1 
ATOM   995  C CH2 . TRP B  1 38 ? 4.19329   3.11963   -27.22034 1.000 8.21547  ? 36  TRP C CH2 1 
ATOM   996  N N   . TYR B  1 39 ? 7.89952   3.32054   -21.13617 1.000 9.33272  ? 37  TYR C N   1 
ATOM   997  C CA  . TYR B  1 39 ? 8.01411   2.88242   -19.75545 1.000 8.75773  ? 37  TYR C CA  1 
ATOM   998  C C   . TYR B  1 39 ? 6.72999   2.16001   -19.38440 1.000 9.08319  ? 37  TYR C C   1 
ATOM   999  O O   . TYR B  1 39 ? 5.69400   2.31586   -20.03525 1.000 11.19058 ? 37  TYR C O   1 
ATOM   1000 C CB  . TYR B  1 39 ? 8.28684   4.05431   -18.80060 1.000 10.63410 ? 37  TYR C CB  1 
ATOM   1001 C CG  . TYR B  1 39 ? 7.19714   5.08980   -18.81974 1.000 12.13068 ? 37  TYR C CG  1 
ATOM   1002 C CD1 . TYR B  1 39 ? 7.16417   6.08479   -19.79186 1.000 13.33371 ? 37  TYR C CD1 1 
ATOM   1003 C CD2 . TYR B  1 39 ? 6.18218   5.06111   -17.87192 1.000 12.64230 ? 37  TYR C CD2 1 
ATOM   1004 C CE1 . TYR B  1 39 ? 6.15450   7.02635   -19.81164 1.000 13.82055 ? 37  TYR C CE1 1 
ATOM   1005 C CE2 . TYR B  1 39 ? 5.17659   5.99962   -17.88075 1.000 14.44583 ? 37  TYR C CE2 1 
ATOM   1006 C CZ  . TYR B  1 39 ? 5.16247   6.97607   -18.84953 1.000 15.43814 ? 37  TYR C CZ  1 
ATOM   1007 O OH  . TYR B  1 39 ? 4.14810   7.90243   -18.85004 1.000 17.69189 ? 37  TYR C OH  1 
ATOM   1008 N N   . THR B  1 40 ? 6.80337   1.35942   -18.33638 1.000 9.00577  ? 38  THR C N   1 
ATOM   1009 C CA  . THR B  1 40 ? 5.65858   0.56969   -17.92426 1.000 8.58922  ? 38  THR C CA  1 
ATOM   1010 C C   . THR B  1 40 ? 4.71109   1.40568   -17.07401 1.000 8.28006  ? 38  THR C C   1 
ATOM   1011 O O   . THR B  1 40 ? 5.13532   2.16602   -16.19695 1.000 9.35458  ? 38  THR C O   1 
ATOM   1012 C CB  . THR B  1 40 ? 6.13998   -0.67236  -17.18070 1.000 9.75347  ? 38  THR C CB  1 
ATOM   1013 O OG1 . THR B  1 40 ? 6.87345   -1.49425  -18.10256 1.000 11.67109 ? 38  THR C OG1 1 
ATOM   1014 C CG2 . THR B  1 40 ? 4.96203   -1.45228  -16.60055 1.000 10.96775 ? 38  THR C CG2 1 
ATOM   1015 N N   . GLY B  1 41 ? 3.41635   1.28756   -17.36813 1.000 8.05019  ? 39  GLY C N   1 
ATOM   1016 C CA  . GLY B  1 41 ? 2.38865   2.00279   -16.64748 1.000 8.83499  ? 39  GLY C CA  1 
ATOM   1017 C C   . GLY B  1 41 ? 1.76346   1.18633   -15.52730 1.000 8.00621  ? 39  GLY C C   1 
ATOM   1018 O O   . GLY B  1 41 ? 2.07617   0.02257   -15.29793 1.000 8.85308  ? 39  GLY C O   1 
ATOM   1019 N N   . ALA B  1 42 ? 0.84059   1.84256   -14.82377 1.000 8.62294  ? 40  ALA C N   1 
ATOM   1020 C CA  . ALA B  1 42 ? 0.23297   1.25351   -13.63788 1.000 9.40665  ? 40  ALA C CA  1 
ATOM   1021 C C   . ALA B  1 42 ? -0.85882  0.23503   -13.94510 1.000 8.32076  ? 40  ALA C C   1 
ATOM   1022 O O   . ALA B  1 42 ? -1.22828  -0.52838  -13.04613 1.000 10.43151 ? 40  ALA C O   1 
ATOM   1023 C CB  . ALA B  1 42 ? -0.32732  2.35068   -12.73164 1.000 10.69798 ? 40  ALA C CB  1 
ATOM   1024 N N   . PHE B  1 43 ? -1.40620  0.20157   -15.16014 1.000 8.55484  ? 41  PHE C N   1 
ATOM   1025 C CA  . PHE B  1 43 ? -2.50286  -0.72482  -15.41561 1.000 8.06627  ? 41  PHE C CA  1 
ATOM   1026 C C   . PHE B  1 43 ? -2.01723  -2.16453  -15.32922 1.000 8.68934  ? 41  PHE C C   1 
ATOM   1027 O O   . PHE B  1 43 ? -1.07387  -2.55430  -16.02248 1.000 9.66418  ? 41  PHE C O   1 
ATOM   1028 C CB  . PHE B  1 43 ? -3.10028  -0.49545  -16.79762 1.000 8.99057  ? 41  PHE C CB  1 
ATOM   1029 C CG  . PHE B  1 43 ? -4.32451  -1.32876  -17.05384 1.000 9.87373  ? 41  PHE C CG  1 
ATOM   1030 C CD1 . PHE B  1 43 ? -4.22539  -2.62221  -17.53050 1.000 10.81137 ? 41  PHE C CD1 1 
ATOM   1031 C CD2 . PHE B  1 43 ? -5.57983  -0.81611  -16.81408 1.000 15.45789 ? 41  PHE C CD2 1 
ATOM   1032 C CE1 . PHE B  1 43 ? -5.36306  -3.39280  -17.74157 1.000 11.30830 ? 41  PHE C CE1 1 
ATOM   1033 C CE2 . PHE B  1 43 ? -6.71484  -1.57779  -17.04082 1.000 14.66482 ? 41  PHE C CE2 1 
ATOM   1034 C CZ  . PHE B  1 43 ? -6.60185  -2.86927  -17.49603 1.000 14.40977 ? 41  PHE C CZ  1 
ATOM   1035 N N   . ASN B  1 44 ? -2.69727  -2.97278  -14.51764 1.000 10.32647 ? 42  ASN C N   1 
ATOM   1036 C CA  . ASN B  1 44 ? -2.35633  -4.38828  -14.41442 1.000 10.43453 ? 42  ASN C CA  1 
ATOM   1037 C C   . ASN B  1 44 ? -3.60557  -5.08962  -13.88145 1.000 11.79594 ? 42  ASN C C   1 
ATOM   1038 O O   . ASN B  1 44 ? -3.92460  -4.96562  -12.69587 1.000 13.67623 ? 42  ASN C O   1 
ATOM   1039 C CB  . ASN B  1 44 ? -1.16181  -4.57791  -13.49135 1.000 14.06224 ? 42  ASN C CB  1 
ATOM   1040 C CG  . ASN B  1 44 ? -0.66054  -6.01009  -13.45927 1.000 15.60956 ? 42  ASN C CG  1 
ATOM   1041 O OD1 . ASN B  1 44 ? -1.44202  -6.95537  -13.34320 1.000 23.53077 ? 42  ASN C OD1 1 
ATOM   1042 N ND2 . ASN B  1 44 ? 0.65314   -6.17648  -13.55601 1.000 20.72503 ? 42  ASN C ND2 1 
ATOM   1043 N N   . GLU B  1 45 ? -4.30859  -5.79555  -14.75572 1.000 10.86701 ? 43  GLU C N   1 
ATOM   1044 C CA  . GLU B  1 45 ? -5.56623  -6.43453  -14.39433 1.000 12.76032 ? 43  GLU C CA  1 
ATOM   1045 C C   . GLU B  1 45 ? -5.68455  -7.73183  -15.17199 1.000 11.23956 ? 43  GLU C C   1 
ATOM   1046 O O   . GLU B  1 45 ? -5.06044  -7.88625  -16.22956 1.000 11.53890 ? 43  GLU C O   1 
ATOM   1047 C CB  . GLU B  1 45 ? -6.77088  -5.53934  -14.72616 1.000 14.80376 ? 43  GLU C CB  1 
ATOM   1048 C CG  . GLU B  1 45 ? -6.79922  -4.19789  -14.01426 1.000 18.48940 ? 43  GLU C CG  1 
ATOM   1049 C CD  . GLU B  1 45 ? -6.92443  -4.32943  -12.51399 1.000 20.07520 ? 43  GLU C CD  1 
ATOM   1050 O OE1 . GLU B  1 45 ? -7.39597  -5.38721  -12.03790 1.000 21.84558 ? 43  GLU C OE1 1 
ATOM   1051 O OE2 . GLU B  1 45 ? -6.53904  -3.37684  -11.80435 1.000 26.80707 ? 43  GLU C OE2 1 
ATOM   1052 N N   . PRO B  1 46 ? -6.50327  -8.67195  -14.70064 1.000 11.17294 ? 44  PRO C N   1 
ATOM   1053 C CA  . PRO B  1 46 ? -6.68522  -9.91922  -15.44794 1.000 10.80129 ? 44  PRO C CA  1 
ATOM   1054 C C   . PRO B  1 46 ? -7.36678  -9.67767  -16.78397 1.000 11.67111 ? 44  PRO C C   1 
ATOM   1055 O O   . PRO B  1 46 ? -8.19237  -8.77334  -16.93960 1.000 12.13130 ? 44  PRO C O   1 
ATOM   1056 C CB  . PRO B  1 46 ? -7.58089  -10.75794 -14.52617 1.000 12.43309 ? 44  PRO C CB  1 
ATOM   1057 C CG  . PRO B  1 46 ? -7.40302  -10.17410 -13.16797 1.000 16.72245 ? 44  PRO C CG  1 
ATOM   1058 C CD  . PRO B  1 46 ? -7.18664  -8.70971  -13.39451 1.000 11.79207 ? 44  PRO C CD  1 
ATOM   1059 N N   . GLY B  1 47 ? -7.01926  -10.51072 -17.75348 1.000 10.69480 ? 45  GLY C N   1 
ATOM   1060 C CA  . GLY B  1 47 ? -7.71564  -10.48812 -19.01810 1.000 12.16566 ? 45  GLY C CA  1 
ATOM   1061 C C   . GLY B  1 47 ? -7.02131  -11.29329 -20.09234 1.000 11.71771 ? 45  GLY C C   1 
ATOM   1062 O O   . GLY B  1 47 ? -5.79046  -11.38702 -20.11780 1.000 12.37110 ? 45  GLY C O   1 
ATOM   1063 N N   . ASP B  1 48 ? -7.81309  -11.88109 -20.98588 1.000 10.38461 ? 46  ASP C N   1 
ATOM   1064 C CA  . ASP B  1 48 ? -7.30764  -12.58408 -22.15051 1.000 12.36592 ? 46  ASP C CA  1 
ATOM   1065 C C   . ASP B  1 48 ? -7.54477  -11.81943 -23.44175 1.000 10.32331 ? 46  ASP C C   1 
ATOM   1066 O O   . ASP B  1 48 ? -6.95759  -12.16964 -24.46850 1.000 12.90918 ? 46  ASP C O   1 
ATOM   1067 C CB  . ASP B  1 48 ? -7.95012  -13.97391 -22.24143 1.000 15.57831 ? 46  ASP C CB  1 
ATOM   1068 C CG  . ASP B  1 48 ? -7.65122  -14.82822 -21.02367 1.000 16.42072 ? 46  ASP C CG  1 
ATOM   1069 O OD1 . ASP B  1 48 ? -6.46796  -14.90952 -20.63969 1.000 24.04824 ? 46  ASP C OD1 1 
ATOM   1070 O OD2 . ASP B  1 48 ? -8.59798  -15.39265 -20.43802 1.000 23.18975 ? 46  ASP C OD2 1 
ATOM   1071 N N   . ASN B  1 49 ? -8.37207  -10.77664 -23.40787 1.000 10.14274 ? 47  ASN C N   1 
ATOM   1072 C CA  . ASN B  1 49 ? -8.63454  -9.92781  -24.55702 1.000 9.93176  ? 47  ASN C CA  1 
ATOM   1073 C C   . ASN B  1 49 ? -8.79538  -8.50278  -24.05860 1.000 9.95120  ? 47  ASN C C   1 
ATOM   1074 O O   . ASN B  1 49 ? -9.30862  -8.27620  -22.96081 1.000 10.21992 ? 47  ASN C O   1 
ATOM   1075 C CB  . ASN B  1 49 ? -9.92441  -10.33782 -25.27342 1.000 12.76260 ? 47  ASN C CB  1 
ATOM   1076 C CG  . ASN B  1 49 ? -10.30510 -9.36472  -26.36087 1.000 11.75767 ? 47  ASN C CG  1 
ATOM   1077 O OD1 . ASN B  1 49 ? -11.17435 -8.50362  -26.17743 1.000 11.77161 ? 47  ASN C OD1 1 
ATOM   1078 N ND2 . ASN B  1 49 ? -9.61856  -9.45964  -27.49112 1.000 13.40785 ? 47  ASN C ND2 1 
ATOM   1079 N N   . VAL B  1 50 ? -8.34871  -7.53929  -24.86627 1.000 9.73834  ? 48  VAL C N   1 
ATOM   1080 C CA  . VAL B  1 50 ? -8.36245  -6.13801  -24.46473 1.000 9.18763  ? 48  VAL C CA  1 
ATOM   1081 C C   . VAL B  1 50 ? -8.75619  -5.23736  -25.63188 1.000 8.34466  ? 48  VAL C C   1 
ATOM   1082 O O   . VAL B  1 50 ? -8.35421  -5.45909  -26.77697 1.000 8.65567  ? 48  VAL C O   1 
ATOM   1083 C CB  . VAL B  1 50 ? -7.01343  -5.72448  -23.83028 1.000 9.31354  ? 48  VAL C CB  1 
ATOM   1084 C CG1 . VAL B  1 50 ? -5.86311  -5.85002  -24.82979 1.000 10.76218 ? 48  VAL C CG1 1 
ATOM   1085 C CG2 . VAL B  1 50 ? -7.09170  -4.32580  -23.26068 1.000 11.00128 ? 48  VAL C CG2 1 
ATOM   1086 N N   . SER B  1 51 ? -9.54802  -4.21321  -25.32419 1.000 7.92638  ? 49  SER C N   1 
ATOM   1087 C CA  . SER B  1 51 ? -9.75243  -3.06665  -26.19428 1.000 7.18854  ? 49  SER C CA  1 
ATOM   1088 C C   . SER B  1 51 ? -9.67538  -1.81502  -25.33446 1.000 7.27669  ? 49  SER C C   1 
ATOM   1089 O O   . SER B  1 51 ? -9.73186  -1.88283  -24.10394 1.000 7.82128  ? 49  SER C O   1 
ATOM   1090 C CB  . SER B  1 51 ? -11.08884 -3.12709  -26.94832 1.000 7.61700  ? 49  SER C CB  1 
ATOM   1091 O OG  . SER B  1 51 ? -12.20132 -2.98102  -26.08046 1.000 8.87861  ? 49  SER C OG  1 
ATOM   1092 N N   . VAL B  1 52 ? -9.53110  -0.65882  -25.98055 1.000 7.05743  ? 50  VAL C N   1 
ATOM   1093 C CA  . VAL B  1 52 ? -9.35294  0.58501   -25.24419 1.000 8.03214  ? 50  VAL C CA  1 
ATOM   1094 C C   . VAL B  1 52 ? -9.91696  1.74529   -26.04794 1.000 7.69447  ? 50  VAL C C   1 
ATOM   1095 O O   . VAL B  1 52 ? -9.90896  1.74033   -27.28164 1.000 8.82869  ? 50  VAL C O   1 
ATOM   1096 C CB  . VAL B  1 52 ? -7.86008  0.82919   -24.90801 1.000 8.86162  ? 50  VAL C CB  1 
ATOM   1097 C CG1 . VAL B  1 52 ? -7.02850  0.98751   -26.18744 1.000 9.31541  ? 50  VAL C CG1 1 
ATOM   1098 C CG2 . VAL B  1 52 ? -7.68267  2.03394   -23.99837 1.000 9.31673  ? 50  VAL C CG2 1 
ATOM   1099 N N   . THR B  1 53 ? -10.39432 2.75793   -25.33364 1.000 7.47309  ? 51  THR C N   1 
ATOM   1100 C CA  . THR B  1 53 ? -10.67034 4.05631   -25.92108 1.000 7.70553  ? 51  THR C CA  1 
ATOM   1101 C C   . THR B  1 53 ? -10.28675 5.11660   -24.89983 1.000 8.03383  ? 51  THR C C   1 
ATOM   1102 O O   . THR B  1 53 ? -10.15720 4.82860   -23.70766 1.000 9.61116  ? 51  THR C O   1 
ATOM   1103 C CB  . THR B  1 53 ? -12.14381 4.16987   -26.36198 1.000 8.50079  ? 51  THR C CB  1 
ATOM   1104 O OG1 . THR B  1 53 ? -12.33276 5.36496   -27.12967 1.000 9.13498  ? 51  THR C OG1 1 
ATOM   1105 C CG2 . THR B  1 53 ? -13.09632 4.20167   -25.16874 1.000 9.32117  ? 51  THR C CG2 1 
ATOM   1106 N N   . SER B  1 54 ? -10.08164 6.34443   -25.36724 1.000 7.93638  ? 52  SER C N   1 
ATOM   1107 C CA  . SER B  1 54 ? -9.75764  7.43236   -24.45807 1.000 9.23456  ? 52  SER C CA  1 
ATOM   1108 C C   . SER B  1 54 ? -10.28937 8.73303   -25.03683 1.000 8.81588  ? 52  SER C C   1 
ATOM   1109 O O   . SER B  1 54 ? -10.51199 8.84383   -26.24142 1.000 9.28454  ? 52  SER C O   1 
ATOM   1110 C CB  . SER B  1 54 ? -8.24904  7.53682   -24.21173 1.000 8.79874  ? 52  SER C CB  1 
ATOM   1111 O OG  . SER B  1 54 ? -7.55540  7.90365   -25.39441 1.000 9.01494  ? 52  SER C OG  1 
ATOM   1112 N N   . TRP B  1 55 ? -10.50014 9.71703   -24.16315 1.000 8.75752  ? 53  TRP C N   1 
ATOM   1113 C CA  . TRP B  1 55 ? -10.93888 11.03875  -24.58541 1.000 10.11266 ? 53  TRP C CA  1 
ATOM   1114 C C   . TRP B  1 55 ? -10.34736 12.06870  -23.63712 1.000 10.04739 ? 53  TRP C C   1 
ATOM   1115 O O   . TRP B  1 55 ? -10.09287 11.78324  -22.46481 1.000 11.23118 ? 53  TRP C O   1 
ATOM   1116 C CB  . TRP B  1 55 ? -12.47132 11.17557  -24.59844 1.000 10.76375 ? 53  TRP C CB  1 
ATOM   1117 C CG  . TRP B  1 55 ? -13.09375 11.02610  -23.23591 1.000 9.92515  ? 53  TRP C CG  1 
ATOM   1118 C CD1 . TRP B  1 55 ? -13.40416 12.02818  -22.35858 1.000 12.18832 ? 53  TRP C CD1 1 
ATOM   1119 C CD2 . TRP B  1 55 ? -13.46026 9.79919   -22.59102 1.000 10.00429 ? 53  TRP C CD2 1 
ATOM   1120 N NE1 . TRP B  1 55 ? -13.94620 11.49777  -21.21008 1.000 12.74670 ? 53  TRP C NE1 1 
ATOM   1121 C CE2 . TRP B  1 55 ? -13.98646 10.13155  -21.32470 1.000 10.49077 ? 53  TRP C CE2 1 
ATOM   1122 C CE3 . TRP B  1 55 ? -13.39144 8.45165   -22.96208 1.000 9.85139  ? 53  TRP C CE3 1 
ATOM   1123 C CZ2 . TRP B  1 55 ? -14.44089 9.16512   -20.42625 1.000 11.15633 ? 53  TRP C CZ2 1 
ATOM   1124 C CZ3 . TRP B  1 55 ? -13.85078 7.49340   -22.07062 1.000 9.55254  ? 53  TRP C CZ3 1 
ATOM   1125 C CH2 . TRP B  1 55 ? -14.36318 7.85494   -20.81453 1.000 11.07936 ? 53  TRP C CH2 1 
ATOM   1126 N N   . LEU B  1 56 ? -10.13764 13.26949  -24.15875 1.000 10.94113 ? 54  LEU C N   1 
ATOM   1127 C CA  . LEU B  1 56 ? -9.66027  14.39377  -23.37079 1.000 11.97185 ? 54  LEU C CA  1 
ATOM   1128 C C   . LEU B  1 56 ? -10.83134 15.23659  -22.89233 1.000 14.38179 ? 54  LEU C C   1 
ATOM   1129 O O   . LEU B  1 56 ? -11.81477 15.42953  -23.61266 1.000 15.95548 ? 54  LEU C O   1 
ATOM   1130 C CB  . LEU B  1 56 ? -8.73316  15.27860  -24.20427 1.000 14.73908 ? 54  LEU C CB  1 
ATOM   1131 C CG  . LEU B  1 56 ? -7.35790  14.70391  -24.51451 1.000 14.19836 ? 54  LEU C CG  1 
ATOM   1132 C CD1 . LEU B  1 56 ? -6.74024  15.43229  -25.69508 1.000 16.37686 ? 54  LEU C CD1 1 
ATOM   1133 C CD2 . LEU B  1 56 ? -6.45673  14.80752  -23.29671 1.000 16.88638 ? 54  LEU C CD2 1 
ATOM   1134 N N   . VAL B  1 57 ? -10.71531 15.73162  -21.67032 1.000 14.17212 ? 55  VAL C N   1 
ATOM   1135 C CA  . VAL B  1 57 ? -11.54450 16.81613  -21.16713 1.000 16.28003 ? 55  VAL C CA  1 
ATOM   1136 C C   . VAL B  1 57 ? -10.55907 17.93317  -20.85750 1.000 21.95875 ? 55  VAL C C   1 
ATOM   1137 O O   . VAL B  1 57 ? -9.84611  17.88284  -19.84735 1.000 19.47342 ? 55  VAL C O   1 
ATOM   1138 C CB  . VAL B  1 57 ? -12.35265 16.40856  -19.93277 1.000 16.60327 ? 55  VAL C CB  1 
ATOM   1139 C CG1 . VAL B  1 57 ? -13.10541 17.60661  -19.37925 1.000 23.31241 ? 55  VAL C CG1 1 
ATOM   1140 C CG2 . VAL B  1 57 ? -13.31910 15.28547  -20.28924 1.000 19.30103 ? 55  VAL C CG2 1 
ATOM   1141 N N   . GLY B  1 58 ? -10.47734 18.91874  -21.74861 1.000 20.73660 ? 56  GLY C N   1 
ATOM   1142 C CA  . GLY B  1 58 ? -9.39798  19.88372  -21.68831 1.000 23.73873 ? 56  GLY C CA  1 
ATOM   1143 C C   . GLY B  1 58 ? -8.06717  19.21703  -21.97033 1.000 24.61315 ? 56  GLY C C   1 
ATOM   1144 O O   . GLY B  1 58 ? -7.83633  18.71652  -23.07583 1.000 26.58361 ? 56  GLY C O   1 
ATOM   1145 N N   . SER B  1 59 ? -7.18418  19.19249  -20.97404 1.000 27.85305 ? 57  SER C N   1 
ATOM   1146 C CA  . SER B  1 59 ? -5.91702  18.48141  -21.07476 1.000 28.82817 ? 57  SER C CA  1 
ATOM   1147 C C   . SER B  1 59 ? -5.86718  17.24638  -20.18226 1.000 21.62887 ? 57  SER C C   1 
ATOM   1148 O O   . SER B  1 59 ? -4.80964  16.61715  -20.07022 1.000 29.68317 ? 57  SER C O   1 
ATOM   1149 C CB  . SER B  1 59 ? -4.74517  19.42044  -20.77812 1.000 36.81597 ? 57  SER C CB  1 
ATOM   1150 O OG  . SER B  1 59 ? -4.94498  20.10998  -19.55723 1.000 43.59825 ? 57  SER C OG  1 
ATOM   1151 N N   . ALA B  1 60 ? -6.98360  16.88138  -19.55275 1.000 21.55032 ? 58  ALA C N   1 
ATOM   1152 C CA  . ALA B  1 60 ? -7.05253  15.69478  -18.70857 1.000 18.03243 ? 58  ALA C CA  1 
ATOM   1153 C C   . ALA B  1 60 ? -7.49014  14.49552  -19.54140 1.000 14.14283 ? 58  ALA C C   1 
ATOM   1154 O O   . ALA B  1 60 ? -8.54057  14.53354  -20.18900 1.000 15.48935 ? 58  ALA C O   1 
ATOM   1155 C CB  . ALA B  1 60 ? -8.04725  15.91261  -17.56816 1.000 21.52297 ? 58  ALA C CB  1 
ATOM   1156 N N   . ILE B  1 61 ? -6.69711  13.42794  -19.50770 1.000 15.57725 ? 59  ILE C N   1 
ATOM   1157 C CA  . ILE B  1 61 ? -7.01929  12.21180  -20.24653 1.000 11.80964 ? 59  ILE C CA  1 
ATOM   1158 C C   . ILE B  1 61 ? -7.91932  11.31989  -19.40274 1.000 11.33547 ? 59  ILE C C   1 
ATOM   1159 O O   . ILE B  1 61 ? -7.76557  11.21278  -18.17944 1.000 12.75319 ? 59  ILE C O   1 
ATOM   1160 C CB  . ILE B  1 61 ? -5.74527  11.46843  -20.69473 1.000 12.98291 ? 59  ILE C CB  1 
ATOM   1161 C CG1 . ILE B  1 61 ? -6.09803  10.37092  -21.70091 1.000 12.38514 ? 59  ILE C CG1 1 
ATOM   1162 C CG2 . ILE B  1 61 ? -5.01782  10.86339  -19.50527 1.000 14.24473 ? 59  ILE C CG2 1 
ATOM   1163 C CD1 . ILE B  1 61 ? -6.72518  10.89233  -22.98705 1.000 11.44575 ? 59  ILE C CD1 1 
ATOM   1164 N N   . HIS B  1 62 ? -8.87508  10.68380  -20.06919 1.000 10.11355 ? 60  HIS C N   1 
ATOM   1165 C CA  . HIS B  1 62 ? -9.71739  9.65593   -19.48236 1.000 10.57386 ? 60  HIS C CA  1 
ATOM   1166 C C   . HIS B  1 62 ? -9.59519  8.42879   -20.36751 1.000 8.78719  ? 60  HIS C C   1 
ATOM   1167 O O   . HIS B  1 62 ? -9.72359  8.53389   -21.59087 1.000 10.58889 ? 60  HIS C O   1 
ATOM   1168 C CB  . HIS B  1 62 ? -11.16269 10.14258  -19.43117 1.000 11.80676 ? 60  HIS C CB  1 
ATOM   1169 C CG  . HIS B  1 62 ? -11.33392 11.37601  -18.60484 1.000 13.34095 ? 60  HIS C CG  1 
ATOM   1170 N ND1 . HIS B  1 62 ? -11.69731 11.33220  -17.27664 1.000 13.72064 ? 60  HIS C ND1 1 
ATOM   1171 C CD2 . HIS B  1 62 ? -11.15208 12.68376  -18.90417 1.000 14.36714 ? 60  HIS C CD2 1 
ATOM   1172 C CE1 . HIS B  1 62 ? -11.74831 12.56246  -16.79614 1.000 15.40062 ? 60  HIS C CE1 1 
ATOM   1173 N NE2 . HIS B  1 62 ? -11.42412 13.40091  -17.76385 1.000 18.72628 ? 60  HIS C NE2 1 
ATOM   1174 N N   . ILE B  1 63 ? -9.30743  7.28346   -19.76216 1.000 8.76042  ? 61  ILE C N   1 
ATOM   1175 C CA  . ILE B  1 63 ? -9.06365  6.05467   -20.50119 1.000 8.38900  ? 61  ILE C CA  1 
ATOM   1176 C C   . ILE B  1 63 ? -10.03588 4.99800   -20.00446 1.000 8.17049  ? 61  ILE C C   1 
ATOM   1177 O O   . ILE B  1 63 ? -10.29551 4.90117   -18.79937 1.000 8.74652  ? 61  ILE C O   1 
ATOM   1178 C CB  . ILE B  1 63 ? -7.61316  5.56011   -20.32171 1.000 8.55742  ? 61  ILE C CB  1 
ATOM   1179 C CG1 . ILE B  1 63 ? -6.59791  6.69324   -20.51830 1.000 8.79228  ? 61  ILE C CG1 1 
ATOM   1180 C CG2 . ILE B  1 63 ? -7.32389  4.41619   -21.28085 1.000 8.85183  ? 61  ILE C CG2 1 
ATOM   1181 C CD1 . ILE B  1 63 ? -5.17718  6.31934   -20.10426 1.000 10.96508 ? 61  ILE C CD1 1 
ATOM   1182 N N   . ARG B  1 64 ? -10.57542 4.20630   -20.92768 1.000 7.39943  ? 62  ARG C N   1 
ATOM   1183 C CA  . ARG B  1 64 ? -11.40360 3.05668   -20.58073 1.000 8.24814  ? 62  ARG C CA  1 
ATOM   1184 C C   . ARG B  1 64 ? -10.82242 1.83512   -21.26674 1.000 7.82450  ? 62  ARG C C   1 
ATOM   1185 O O   . ARG B  1 64 ? -10.70768 1.80494   -22.49650 1.000 8.34205  ? 62  ARG C O   1 
ATOM   1186 C CB  . ARG B  1 64 ? -12.86104 3.26191   -20.99872 1.000 7.68187  ? 62  ARG C CB  1 
ATOM   1187 C CG  . ARG B  1 64 ? -13.54830 4.43119   -20.31413 1.000 8.07775  ? 62  ARG C CG  1 
ATOM   1188 C CD  . ARG B  1 64 ? -13.66293 4.22650   -18.81306 1.000 9.55442  ? 62  ARG C CD  1 
ATOM   1189 N NE  . ARG B  1 64 ? -14.34688 5.33412   -18.14854 1.000 9.11766  ? 62  ARG C NE  1 
ATOM   1190 C CZ  . ARG B  1 64 ? -13.73715 6.40562   -17.66332 1.000 9.80170  ? 62  ARG C CZ  1 
ATOM   1191 N NH1 . ARG B  1 64 ? -12.41971 6.53748   -17.72578 1.000 10.32703 ? 62  ARG C NH1 1 
ATOM   1192 N NH2 . ARG B  1 64 ? -14.46591 7.37737   -17.11335 1.000 10.18727 ? 62  ARG C NH2 1 
ATOM   1193 N N   . VAL B  1 65 ? -10.46208 0.83596   -20.47280 1.000 7.88339  ? 63  VAL C N   1 
ATOM   1194 C CA  . VAL B  1 65 ? -9.93482  -0.43019  -20.95927 1.000 7.83684  ? 63  VAL C CA  1 
ATOM   1195 C C   . VAL B  1 65 ? -10.98662 -1.50155  -20.71358 1.000 7.08381  ? 63  VAL C C   1 
ATOM   1196 O O   . VAL B  1 65 ? -11.50147 -1.62796  -19.59391 1.000 8.87151  ? 63  VAL C O   1 
ATOM   1197 C CB  . VAL B  1 65 ? -8.61314  -0.78261  -20.25832 1.000 9.40774  ? 63  VAL C CB  1 
ATOM   1198 C CG1 . VAL B  1 65 ? -8.14080  -2.16241  -20.67445 1.000 10.54232 ? 63  VAL C CG1 1 
ATOM   1199 C CG2 . VAL B  1 65 ? -7.55554  0.26928   -20.55497 1.000 9.31513  ? 63  VAL C CG2 1 
ATOM   1200 N N   . TYR B  1 66 ? -11.31892 -2.25504  -21.75558 1.000 7.64761  ? 64  TYR C N   1 
ATOM   1201 C CA  . TYR B  1 66 ? -12.31248 -3.32110  -21.68626 1.000 7.87575  ? 64  TYR C CA  1 
ATOM   1202 C C   . TYR B  1 66 ? -11.56575 -4.64468  -21.70196 1.000 8.14064  ? 64  TYR C C   1 
ATOM   1203 O O   . TYR B  1 66 ? -10.99202 -5.02668  -22.72410 1.000 8.51113  ? 64  TYR C O   1 
ATOM   1204 C CB  . TYR B  1 66 ? -13.36447 -3.18095  -22.79803 1.000 8.25497  ? 64  TYR C CB  1 
ATOM   1205 C CG  . TYR B  1 66 ? -14.07354 -1.86582  -22.62345 1.000 7.59947  ? 64  TYR C CG  1 
ATOM   1206 C CD1 . TYR B  1 66 ? -15.14525 -1.74185  -21.74289 1.000 8.24466  ? 64  TYR C CD1 1 
ATOM   1207 C CD2 . TYR B  1 66 ? -13.61246 -0.72352  -23.25750 1.000 7.83226  ? 64  TYR C CD2 1 
ATOM   1208 C CE1 . TYR B  1 66 ? -15.75186 -0.51467  -21.52435 1.000 8.43045  ? 64  TYR C CE1 1 
ATOM   1209 C CE2 . TYR B  1 66 ? -14.19959 0.49725   -23.03610 1.000 7.90649  ? 64  TYR C CE2 1 
ATOM   1210 C CZ  . TYR B  1 66 ? -15.26799 0.60002   -22.16634 1.000 7.73868  ? 64  TYR C CZ  1 
ATOM   1211 O OH  . TYR B  1 66 ? -15.82978 1.83385   -21.94742 1.000 8.91567  ? 64  TYR C OH  1 
ATOM   1212 N N   . ALA B  1 67 ? -11.53484 -5.30338  -20.54556 1.000 8.03799  ? 65  ALA C N   1 
ATOM   1213 C CA  . ALA B  1 67 ? -10.77262 -6.52293  -20.32093 1.000 9.97999  ? 65  ALA C CA  1 
ATOM   1214 C C   . ALA B  1 67 ? -11.74594 -7.68756  -20.26194 1.000 11.18244 ? 65  ALA C C   1 
ATOM   1215 O O   . ALA B  1 67 ? -12.69414 -7.66276  -19.47105 1.000 12.05438 ? 65  ALA C O   1 
ATOM   1216 C CB  . ALA B  1 67 ? -10.04449 -6.42791  -18.98044 1.000 10.09469 ? 65  ALA C CB  1 
ATOM   1217 N N   . SER B  1 68 ? -11.52591 -8.70171  -21.08480 1.000 10.01768 ? 66  SER C N   1 
ATOM   1218 C CA  . SER B  1 68 ? -12.43229 -9.83759  -21.13098 1.000 11.15074 ? 66  SER C CA  1 
ATOM   1219 C C   . SER B  1 68 ? -11.72088 -11.11340 -20.71721 1.000 11.40536 ? 66  SER C C   1 
ATOM   1220 O O   . SER B  1 68 ? -10.60158 -11.38866 -21.16508 1.000 13.36122 ? 66  SER C O   1 
ATOM   1221 C CB  . SER B  1 68 ? -13.05133 -9.99678  -22.51242 1.000 13.06978 ? 66  SER C CB  1 
ATOM   1222 O OG  . SER B  1 68 ? -13.82018 -8.85122  -22.83275 1.000 11.78999 ? 66  SER C OG  1 
ATOM   1223 N N   . THR B  1 69 ? -12.39088 -11.88067 -19.86273 1.000 13.51182 ? 67  THR C N   1 
ATOM   1224 C CA  . THR B  1 69 ? -11.97524 -13.20995 -19.44677 1.000 17.31940 ? 67  THR C CA  1 
ATOM   1225 C C   . THR B  1 69 ? -13.20765 -14.09132 -19.55014 1.000 16.77589 ? 67  THR C C   1 
ATOM   1226 O O   . THR B  1 69 ? -14.25974 -13.74719 -19.00302 1.000 16.48312 ? 67  THR C O   1 
ATOM   1227 C CB  . THR B  1 69 ? -11.49438 -13.18425 -17.99545 1.000 21.90720 ? 67  THR C CB  1 
ATOM   1228 O OG1 . THR B  1 69 ? -10.38685 -12.28269 -17.86626 1.000 20.80849 ? 67  THR C OG1 1 
ATOM   1229 C CG2 . THR B  1 69 ? -11.06416 -14.56948 -17.56185 1.000 25.06202 ? 67  THR C CG2 1 
ATOM   1230 N N   . GLY B  1 70 ? -13.08871 -15.21040 -20.25539 1.000 18.87453 ? 68  GLY C N   1 
ATOM   1231 C CA  . GLY B  1 70 ? -14.28275 -15.99191 -20.54152 1.000 19.46988 ? 68  GLY C CA  1 
ATOM   1232 C C   . GLY B  1 70 ? -15.24095 -15.16689 -21.37998 1.000 18.91411 ? 68  GLY C C   1 
ATOM   1233 O O   . GLY B  1 70 ? -14.86527 -14.60687 -22.41606 1.000 24.50449 ? 68  GLY C O   1 
ATOM   1234 N N   . THR B  1 71 ? -16.49298 -15.06984 -20.93243 1.000 17.27851 ? 69  THR C N   1 
ATOM   1235 C CA  . THR B  1 71 ? -17.47769 -14.20083 -21.56476 1.000 21.34447 ? 69  THR C CA  1 
ATOM   1236 C C   . THR B  1 71 ? -17.75207 -12.93512 -20.76158 1.000 16.38299 ? 69  THR C C   1 
ATOM   1237 O O   . THR B  1 71 ? -18.71568 -12.22469 -21.05890 1.000 19.92218 ? 69  THR C O   1 
ATOM   1238 C CB  . THR B  1 71 ? -18.78859 -14.95111 -21.82230 1.000 24.09487 ? 69  THR C CB  1 
ATOM   1239 O OG1 . THR B  1 71 ? -19.25804 -15.53218 -20.59970 1.000 23.06261 ? 69  THR C OG1 1 
ATOM   1240 C CG2 . THR B  1 71 ? -18.59566 -16.04369 -22.86694 1.000 25.37040 ? 69  THR C CG2 1 
ATOM   1241 N N   . THR B  1 72 ? -16.93333 -12.63564 -19.75898 1.000 14.31648 ? 70  THR C N   1 
ATOM   1242 C CA  . THR B  1 72 ? -17.14859 -11.48792 -18.88814 1.000 13.99156 ? 70  THR C CA  1 
ATOM   1243 C C   . THR B  1 72 ? -16.17864 -10.37501 -19.26520 1.000 11.52752 ? 70  THR C C   1 
ATOM   1244 O O   . THR B  1 72 ? -14.95616 -10.57096 -19.23696 1.000 14.04047 ? 70  THR C O   1 
ATOM   1245 C CB  . THR B  1 72 ? -16.95088 -11.87831 -17.42355 1.000 13.75629 ? 70  THR C CB  1 
ATOM   1246 O OG1 . THR B  1 72 ? -17.79963 -12.98856 -17.10207 1.000 17.47380 ? 70  THR C OG1 1 
ATOM   1247 C CG2 . THR B  1 72 ? -17.28967 -10.71114 -16.50528 1.000 18.59861 ? 70  THR C CG2 1 
ATOM   1248 N N   . THR B  1 73 ? -16.72354 -9.21131  -19.60261 1.000 10.96311 ? 71  THR C N   1 
ATOM   1249 C CA  . THR B  1 73 ? -15.93743 -8.02517  -19.90758 1.000 9.99313  ? 71  THR C CA  1 
ATOM   1250 C C   . THR B  1 73 ? -16.05200 -7.06517  -18.73455 1.000 9.70673  ? 71  THR C C   1 
ATOM   1251 O O   . THR B  1 73 ? -17.16556 -6.70721  -18.32914 1.000 12.32430 ? 71  THR C O   1 
ATOM   1252 C CB  . THR B  1 73 ? -16.45094 -7.36365  -21.18289 1.000 11.17888 ? 71  THR C CB  1 
ATOM   1253 O OG1 . THR B  1 73 ? -16.35124 -8.28950  -22.26516 1.000 12.54694 ? 71  THR C OG1 1 
ATOM   1254 C CG2 . THR B  1 73 ? -15.65523 -6.09834  -21.49045 1.000 11.05354 ? 71  THR C CG2 1 
ATOM   1255 N N   . THR B  1 74 ? -14.91066 -6.66200  -18.18852 1.000 10.39739 ? 72  THR C N   1 
ATOM   1256 C CA  . THR B  1 74 ? -14.83609 -5.68983  -17.11125 1.000 10.05780 ? 72  THR C CA  1 
ATOM   1257 C C   . THR B  1 74 ? -14.21873 -4.41171  -17.66010 1.000 8.56316  ? 72  THR C C   1 
ATOM   1258 O O   . THR B  1 74 ? -13.19069 -4.45891  -18.34711 1.000 10.01981 ? 72  THR C O   1 
ATOM   1259 C CB  . THR B  1 74 ? -13.96582 -6.23731  -15.97471 1.000 10.43163 ? 72  THR C CB  1 
ATOM   1260 O OG1 . THR B  1 74 ? -14.54791 -7.43775  -15.45075 1.000 13.64505 ? 72  THR C OG1 1 
ATOM   1261 C CG2 . THR B  1 74 ? -13.83125 -5.22192  -14.85473 1.000 13.28573 ? 72  THR C CG2 1 
ATOM   1262 N N   . GLU B  1 75 ? -14.83972 -3.27851  -17.36001 1.000 8.42938  ? 73  GLU C N   1 
ATOM   1263 C CA  . GLU B  1 75 ? -14.31384 -1.97702  -17.73966 1.000 8.29859  ? 73  GLU C CA  1 
ATOM   1264 C C   . GLU B  1 75 ? -13.44416 -1.42355  -16.62028 1.000 8.95836  ? 73  GLU C C   1 
ATOM   1265 O O   . GLU B  1 75 ? -13.84170 -1.43617  -15.44997 1.000 9.91723  ? 73  GLU C O   1 
ATOM   1266 C CB  . GLU B  1 75 ? -15.46738 -1.02085  -18.02019 1.000 8.99224  ? 73  GLU C CB  1 
ATOM   1267 C CG  . GLU B  1 75 ? -15.07356 0.41046   -18.30256 1.000 9.02350  ? 73  GLU C CG  1 
ATOM   1268 C CD  . GLU B  1 75 ? -16.28366 1.32993   -18.30908 1.000 8.97508  ? 73  GLU C CD  1 
ATOM   1269 O OE1 . GLU B  1 75 ? -17.05857 1.25808   -17.33482 1.000 9.16488  ? 73  GLU C OE1 1 
ATOM   1270 O OE2 . GLU B  1 75 ? -16.47931 2.10335   -19.27476 1.000 8.96508  ? 73  GLU C OE2 1 
ATOM   1271 N N   . TRP B  1 76 ? -12.26516 -0.93294  -16.99096 1.000 8.04558  ? 74  TRP C N   1 
ATOM   1272 C CA  . TRP B  1 76 ? -11.33842 -0.29396  -16.07469 1.000 8.92456  ? 74  TRP C CA  1 
ATOM   1273 C C   . TRP B  1 76 ? -11.15835 1.15322   -16.49849 1.000 8.43996  ? 74  TRP C C   1 
ATOM   1274 O O   . TRP B  1 76 ? -11.02078 1.44778   -17.69137 1.000 9.06765  ? 74  TRP C O   1 
ATOM   1275 C CB  . TRP B  1 76 ? -9.99822  -1.02567  -16.06754 1.000 9.04522  ? 74  TRP C CB  1 
ATOM   1276 C CG  . TRP B  1 76 ? -10.12456 -2.38972  -15.49316 1.000 9.28927  ? 74  TRP C CG  1 
ATOM   1277 C CD1 . TRP B  1 76 ? -10.26039 -3.55818  -16.17435 1.000 10.81181 ? 74  TRP C CD1 1 
ATOM   1278 C CD2 . TRP B  1 76 ? -10.18803 -2.72247  -14.10449 1.000 12.14208 ? 74  TRP C CD2 1 
ATOM   1279 N NE1 . TRP B  1 76 ? -10.37764 -4.60754  -15.29745 1.000 11.58479 ? 74  TRP C NE1 1 
ATOM   1280 C CE2 . TRP B  1 76 ? -10.33326 -4.11981  -14.01837 1.000 13.06944 ? 74  TRP C CE2 1 
ATOM   1281 C CE3 . TRP B  1 76 ? -10.10628 -1.97594  -12.92443 1.000 14.77068 ? 74  TRP C CE3 1 
ATOM   1282 C CZ2 . TRP B  1 76 ? -10.41312 -4.78651  -12.79824 1.000 18.25113 ? 74  TRP C CZ2 1 
ATOM   1283 C CZ3 . TRP B  1 76 ? -10.18627 -2.63897  -11.71444 1.000 15.94691 ? 74  TRP C CZ3 1 
ATOM   1284 C CH2 . TRP B  1 76 ? -10.33662 -4.03015  -11.66165 1.000 22.81782 ? 74  TRP C CH2 1 
ATOM   1285 N N   . CYS B  1 77 ? -11.16432 2.05406   -15.52224 1.000 9.30095  ? 75  CYS C N   1 
ATOM   1286 C CA  . CYS B  1 77 ? -11.29543 3.47835   -15.77455 1.000 8.67543  ? 75  CYS C CA  1 
ATOM   1287 C C   . CYS B  1 77 ? -10.10952 4.21585   -15.18391 1.000 11.04031 ? 75  CYS C C   1 
ATOM   1288 O O   . CYS B  1 77 ? -9.80828  4.06685   -13.99375 1.000 10.62783 ? 75  CYS C O   1 
ATOM   1289 C CB  . CYS B  1 77 ? -12.56138 4.01280   -15.11250 1.000 10.78663 ? 75  CYS C CB  1 
ATOM   1290 S SG  . CYS B  1 77 ? -14.05572 3.10427   -15.52273 1.000 10.93484 ? 75  CYS C SG  1 
ATOM   1291 N N   . TRP B  1 78 ? -9.45723  5.02282   -16.00890 1.000 9.68658  ? 76  TRP C N   1 
ATOM   1292 C CA  . TRP B  1 78 ? -8.46420  5.98057   -15.55434 1.000 10.15214 ? 76  TRP C CA  1 
ATOM   1293 C C   . TRP B  1 78 ? -9.05916  7.36622   -15.73101 1.000 11.68946 ? 76  TRP C C   1 
ATOM   1294 O O   . TRP B  1 78 ? -9.41394  7.75779   -16.84691 1.000 11.08140 ? 76  TRP C O   1 
ATOM   1295 C CB  . TRP B  1 78 ? -7.16343  5.87279   -16.34972 1.000 9.68834  ? 76  TRP C CB  1 
ATOM   1296 C CG  . TRP B  1 78 ? -6.13296  6.86411   -15.88864 1.000 10.68820 ? 76  TRP C CG  1 
ATOM   1297 C CD1 . TRP B  1 78 ? -5.93677  8.12847   -16.36466 1.000 13.20929 ? 76  TRP C CD1 1 
ATOM   1298 C CD2 . TRP B  1 78 ? -5.17375  6.67934   -14.83844 1.000 10.14676 ? 76  TRP C CD2 1 
ATOM   1299 N NE1 . TRP B  1 78 ? -4.90702  8.73659   -15.68220 1.000 12.51246 ? 76  TRP C NE1 1 
ATOM   1300 C CE2 . TRP B  1 78 ? -4.42105  7.86592   -14.74343 1.000 11.46123 ? 76  TRP C CE2 1 
ATOM   1301 C CE3 . TRP B  1 78 ? -4.87480  5.62312   -13.97974 1.000 9.94566  ? 76  TRP C CE3 1 
ATOM   1302 C CZ2 . TRP B  1 78 ? -3.38618  8.02535   -13.81720 1.000 12.88510 ? 76  TRP C CZ2 1 
ATOM   1303 C CZ3 . TRP B  1 78 ? -3.83353  5.78014   -13.06697 1.000 11.39595 ? 76  TRP C CZ3 1 
ATOM   1304 C CH2 . TRP B  1 78 ? -3.11140  6.97282   -12.99219 1.000 13.78303 ? 76  TRP C CH2 1 
ATOM   1305 N N   . ASP B  1 79 ? -9.17888  8.09939   -14.62906 1.000 11.90010 ? 77  ASP C N   1 
ATOM   1306 C CA  . ASP B  1 79 ? -9.68052  9.46549   -14.65817 1.000 13.05943 ? 77  ASP C CA  1 
ATOM   1307 C C   . ASP B  1 79 ? -8.70428  10.41605  -13.98200 1.000 15.66557 ? 77  ASP C C   1 
ATOM   1308 O O   . ASP B  1 79 ? -9.10178  11.49581  -13.53030 1.000 19.35138 ? 77  ASP C O   1 
ATOM   1309 C CB  . ASP B  1 79 ? -11.08071 9.54593   -14.04916 1.000 17.43349 ? 77  ASP C CB  1 
ATOM   1310 C CG  . ASP B  1 79 ? -12.09087 8.73423   -14.83384 1.000 16.89796 ? 77  ASP C CG  1 
ATOM   1311 O OD1 . ASP B  1 79 ? -12.30718 9.05042   -16.02439 1.000 13.92552 ? 77  ASP C OD1 1 
ATOM   1312 O OD2 . ASP B  1 79 ? -12.64536 7.76757   -14.27103 1.000 20.69601 ? 77  ASP C OD2 1 
ATOM   1313 N N   . GLY B  1 80 ? -7.43811  10.02276  -13.89124 1.000 14.51857 ? 78  GLY C N   1 
ATOM   1314 C CA  . GLY B  1 80 ? -6.38745  10.86252  -13.36680 1.000 17.64920 ? 78  GLY C CA  1 
ATOM   1315 C C   . GLY B  1 80 ? -5.79723  10.39842  -12.05242 1.000 15.55720 ? 78  GLY C C   1 
ATOM   1316 O O   . GLY B  1 80 ? -4.72676  10.88773  -11.67250 1.000 21.41246 ? 78  GLY C O   1 
ATOM   1317 N N   . ASN B  1 81 ? -6.44955  9.47035   -11.34579 1.000 13.48344 ? 79  ASN C N   1 
ATOM   1318 C CA  . ASN B  1 81 ? -5.96412  9.04961   -10.02537 1.000 17.93190 ? 79  ASN C CA  1 
ATOM   1319 C C   . ASN B  1 81 ? -6.29684  7.57121   -9.79645  1.000 15.47882 ? 79  ASN C C   1 
ATOM   1320 O O   . ASN B  1 81 ? -7.15490  7.19614   -8.99713  1.000 18.17315 ? 79  ASN C O   1 
ATOM   1321 C CB  . ASN B  1 81 ? -6.51497  9.93350   -8.90289  1.000 29.64642 ? 79  ASN C CB  1 
ATOM   1322 C CG  . ASN B  1 81 ? -6.01307  9.51548   -7.52686  1.000 38.05083 ? 79  ASN C CG  1 
ATOM   1323 O OD1 . ASN B  1 81 ? -4.82916  9.22443   -7.34348  1.000 33.63849 ? 79  ASN C OD1 1 
ATOM   1324 N ND2 . ASN B  1 81 ? -6.91989  9.47082   -6.55555  1.000 36.81192 ? 79  ASN C ND2 1 
ATOM   1325 N N   . GLY B  1 82 ? -5.59546  6.69765   -10.50759 1.000 14.29523 ? 80  GLY C N   1 
ATOM   1326 C CA  . GLY B  1 82 ? -5.73372  5.27299   -10.30301 1.000 12.85887 ? 80  GLY C CA  1 
ATOM   1327 C C   . GLY B  1 82 ? -6.76988  4.64338   -11.21812 1.000 11.90005 ? 80  GLY C C   1 
ATOM   1328 O O   . GLY B  1 82 ? -7.67612  5.29791   -11.73303 1.000 12.02686 ? 80  GLY C O   1 
ATOM   1329 N N   . TRP B  1 83 ? -6.62983  3.33683   -11.40418 1.000 10.55873 ? 81  TRP C N   1 
ATOM   1330 C CA  . TRP B  1 83 ? -7.56296  2.56664   -12.20659 1.000 10.49613 ? 81  TRP C CA  1 
ATOM   1331 C C   . TRP B  1 83 ? -8.66722  2.01652   -11.31735 1.000 11.39490 ? 81  TRP C C   1 
ATOM   1332 O O   . TRP B  1 83 ? -8.38832  1.39756   -10.28505 1.000 12.87895 ? 81  TRP C O   1 
ATOM   1333 C CB  . TRP B  1 83 ? -6.82213  1.42099   -12.88416 1.000 9.54497  ? 81  TRP C CB  1 
ATOM   1334 C CG  . TRP B  1 83 ? -5.91322  1.89545   -13.97238 1.000 9.00320  ? 81  TRP C CG  1 
ATOM   1335 C CD1 . TRP B  1 83 ? -4.57805  2.16249   -13.87021 1.000 9.78730  ? 81  TRP C CD1 1 
ATOM   1336 C CD2 . TRP B  1 83 ? -6.27831  2.15420   -15.33094 1.000 7.75745  ? 81  TRP C CD2 1 
ATOM   1337 N NE1 . TRP B  1 83 ? -4.09070  2.56467   -15.08655 1.000 8.60848  ? 81  TRP C NE1 1 
ATOM   1338 C CE2 . TRP B  1 83 ? -5.11296  2.57966   -15.99976 1.000 7.92115  ? 81  TRP C CE2 1 
ATOM   1339 C CE3 . TRP B  1 83 ? -7.47639  2.06882   -16.04628 1.000 8.15850  ? 81  TRP C CE3 1 
ATOM   1340 C CZ2 . TRP B  1 83 ? -5.10186  2.90330   -17.35995 1.000 8.61994  ? 81  TRP C CZ2 1 
ATOM   1341 C CZ3 . TRP B  1 83 ? -7.46714  2.39404   -17.40313 1.000 9.43615  ? 81  TRP C CZ3 1 
ATOM   1342 C CH2 . TRP B  1 83 ? -6.28579  2.80500   -18.04116 1.000 8.76267  ? 81  TRP C CH2 1 
ATOM   1343 N N   . THR B  1 84 ? -9.91575  2.22935   -11.73457 1.000 11.03839 ? 82  THR C N   1 
ATOM   1344 C CA  . THR B  1 84 ? -11.09304 1.83009   -10.97464 1.000 13.07641 ? 82  THR C CA  1 
ATOM   1345 C C   . THR B  1 84 ? -12.03453 1.04501   -11.87856 1.000 11.65049 ? 82  THR C C   1 
ATOM   1346 O O   . THR B  1 84 ? -12.11654 1.30112   -13.08228 1.000 10.64924 ? 82  THR C O   1 
ATOM   1347 C CB  . THR B  1 84 ? -11.84236 3.06295   -10.39091 1.000 16.95691 ? 82  THR C CB  1 
ATOM   1348 O OG1 . THR B  1 84 ? -12.36633 3.87112   -11.45448 1.000 19.95032 ? 82  THR C OG1 1 
ATOM   1349 C CG2 . THR B  1 84 ? -10.90694 3.91065   -9.54144  1.000 22.63821 ? 82  THR C CG2 1 
ATOM   1350 N N   . LYS B  1 85 ? -12.75816 0.09322   -11.29452 1.000 11.40005 ? 83  LYS C N   1 
ATOM   1351 C CA  . LYS B  1 85 ? -13.72821 -0.66315  -12.07270 1.000 11.11367 ? 83  LYS C CA  1 
ATOM   1352 C C   . LYS B  1 85 ? -14.93066 0.21197   -12.39904 1.000 11.31445 ? 83  LYS C C   1 
ATOM   1353 O O   . LYS B  1 85 ? -15.47969 0.88622   -11.52129 1.000 11.47783 ? 83  LYS C O   1 
ATOM   1354 C CB  . LYS B  1 85 ? -14.17623 -1.91315  -11.32114 1.000 14.03386 ? 83  LYS C CB  1 
ATOM   1355 C CG  . LYS B  1 85 ? -14.89353 -2.91372  -12.21397 1.000 24.76611 ? 83  LYS C CG  1 
ATOM   1356 C CD  . LYS B  1 85 ? -15.66761 -3.95520  -11.42292 1.000 29.77841 ? 83  LYS C CD  1 
ATOM   1357 C CE  . LYS B  1 85 ? -16.90323 -3.35140  -10.76465 1.000 39.00901 ? 83  LYS C CE  1 
ATOM   1358 N NZ  . LYS B  1 85 ? -17.95678 -2.87619  -11.72309 1.000 19.89535 ? 83  LYS C NZ  1 
ATOM   1359 N N   . GLY B  1 86 ? -15.32860 0.21139   -13.67451 1.000 10.61475 ? 84  GLY C N   1 
ATOM   1360 C CA  . GLY B  1 86 ? -16.45778 0.99718   -14.12489 1.000 11.01852 ? 84  GLY C CA  1 
ATOM   1361 C C   . GLY B  1 86 ? -17.76305 0.21877   -14.10736 1.000 9.62017  ? 84  GLY C C   1 
ATOM   1362 O O   . GLY B  1 86 ? -17.81983 -0.96661  -13.79224 1.000 10.55144 ? 84  GLY C O   1 
ATOM   1363 N N   . ALA B  1 87 ? -18.83104 0.91425   -14.49041 1.000 9.93514  ? 85  ALA C N   1 
ATOM   1364 C CA  . ALA B  1 87 ? -20.18054 0.36607   -14.42241 1.000 9.40663  ? 85  ALA C CA  1 
ATOM   1365 C C   . ALA B  1 87 ? -20.52459 -0.56288  -15.58243 1.000 9.48156  ? 85  ALA C C   1 
ATOM   1366 O O   . ALA B  1 87 ? -21.57207 -1.21657  -15.52644 1.000 10.59167 ? 85  ALA C O   1 
ATOM   1367 C CB  . ALA B  1 87 ? -21.20232 1.50089   -14.36657 1.000 10.30298 ? 85  ALA C CB  1 
ATOM   1368 N N   . TYR B  1 88 ? -19.69424 -0.63174  -16.62743 1.000 8.99544  ? 86  TYR C N   1 
ATOM   1369 C CA  . TYR B  1 88 ? -20.00866 -1.43941  -17.79974 1.000 9.08951  ? 86  TYR C CA  1 
ATOM   1370 C C   . TYR B  1 88 ? -20.42915 -2.85189  -17.42671 1.000 8.80062  ? 86  TYR C C   1 
ATOM   1371 O O   . TYR B  1 88 ? -19.75479 -3.53672  -16.65253 1.000 9.86061  ? 86  TYR C O   1 
ATOM   1372 C CB  . TYR B  1 88 ? -18.78522 -1.52439  -18.71365 1.000 8.51828  ? 86  TYR C CB  1 
ATOM   1373 C CG  . TYR B  1 88 ? -19.01648 -2.38735  -19.93317 1.000 8.49623  ? 86  TYR C CG  1 
ATOM   1374 C CD1 . TYR B  1 88 ? -19.51306 -1.83451  -21.10483 1.000 8.11544  ? 86  TYR C CD1 1 
ATOM   1375 C CD2 . TYR B  1 88 ? -18.74314 -3.74929  -19.91752 1.000 10.42691 ? 86  TYR C CD2 1 
ATOM   1376 C CE1 . TYR B  1 88 ? -19.73914 -2.61002  -22.22452 1.000 9.43387  ? 86  TYR C CE1 1 
ATOM   1377 C CE2 . TYR B  1 88 ? -18.97160 -4.53441  -21.02928 1.000 10.89880 ? 86  TYR C CE2 1 
ATOM   1378 C CZ  . TYR B  1 88 ? -19.46885 -3.95637  -22.18578 1.000 9.25220  ? 86  TYR C CZ  1 
ATOM   1379 O OH  . TYR B  1 88 ? -19.69923 -4.71728  -23.30851 1.000 11.08823 ? 86  TYR C OH  1 
ATOM   1380 N N   . THR B  1 89 ? -21.53440 -3.29065  -18.01684 1.000 9.24011  ? 87  THR C N   1 
ATOM   1381 C CA  . THR B  1 89 ? -21.90823 -4.69051  -18.05447 1.000 10.47280 ? 87  THR C CA  1 
ATOM   1382 C C   . THR B  1 89 ? -22.35579 -5.03628  -19.46498 1.000 11.06832 ? 87  THR C C   1 
ATOM   1383 O O   . THR B  1 89 ? -22.73863 -4.16645  -20.25517 1.000 11.21103 ? 87  THR C O   1 
ATOM   1384 C CB  . THR B  1 89 ? -23.07654 -5.01444  -17.11434 1.000 11.24542 ? 87  THR C CB  1 
ATOM   1385 O OG1 . THR B  1 89 ? -24.21722 -4.23819  -17.49817 1.000 11.30933 ? 87  THR C OG1 1 
ATOM   1386 C CG2 . THR B  1 89 ? -22.71920 -4.73279  -15.66215 1.000 12.37932 ? 87  THR C CG2 1 
ATOM   1387 N N   . ALA B  1 90 ? -22.30503 -6.33261  -19.75601 1.000 13.02556 ? 88  ALA C N   1 
ATOM   1388 C CA  . ALA B  1 90 ? -22.83457 -6.91124  -20.97653 1.000 16.14554 ? 88  ALA C CA  1 
ATOM   1389 C C   . ALA B  1 90 ? -23.40268 -8.27880  -20.62971 1.000 40.92527 ? 88  ALA C C   1 
ATOM   1390 O O   . ALA B  1 90 ? -23.17744 -8.80925  -19.53820 1.000 42.14885 ? 88  ALA C O   1 
ATOM   1391 C CB  . ALA B  1 90 ? -21.75365 -7.04087  -22.05211 1.000 22.71061 ? 88  ALA C CB  1 
ATOM   1392 N N   . THR B  1 91 ? -24.14597 -8.85325  -21.56552 1.000 41.99858 ? 89  THR C N   1 
ATOM   1393 C CA  . THR B  1 91 ? -24.78287 -10.15334 -21.37437 1.000 42.65597 ? 89  THR C CA  1 
ATOM   1394 C C   . THR B  1 91 ? -24.28421 -11.11034 -22.45461 1.000 48.98337 ? 89  THR C C   1 
ATOM   1395 O O   . THR B  1 91 ? -25.00024 -11.42362 -23.41105 1.000 50.25187 ? 89  THR C O   1 
ATOM   1396 C CB  . THR B  1 91 ? -26.30878 -10.01398 -21.37673 1.000 45.55848 ? 89  THR C CB  1 
ATOM   1397 O OG1 . THR B  1 91 ? -26.71142 -9.17413  -22.46547 1.000 44.94578 ? 89  THR C OG1 1 
ATOM   1398 C CG2 . THR B  1 91 ? -26.78533 -9.40433  -20.06613 1.000 34.46300 ? 89  THR C CG2 1 
ATOM   1399 N N   . ASN B  1 92 ? -23.04782 -11.57312 -22.29453 1.000 43.78664 ? 90  ASN C N   1 
ATOM   1400 C CA  . ASN B  1 92 ? -22.44649 -12.51583 -23.23009 1.000 51.59274 ? 90  ASN C CA  1 
ATOM   1401 C C   . ASN B  1 92 ? -22.64907 -13.95114 -22.75101 1.000 51.78158 ? 90  ASN C C   1 
ATOM   1402 O O   . ASN B  1 92 ? -22.71372 -14.88269 -23.55400 1.000 46.21025 ? 90  ASN C O   1 
ATOM   1403 C CB  . ASN B  1 92 ? -20.95245 -12.22478 -23.39468 1.000 43.74131 ? 90  ASN C CB  1 
ATOM   1404 C CG  . ASN B  1 92 ? -20.68155 -10.81482 -23.88654 1.000 36.50594 ? 90  ASN C CG  1 
ATOM   1405 O OD1 . ASN B  1 92 ? -21.31767 -10.33920 -24.82815 1.000 44.59468 ? 90  ASN C OD1 1 
ATOM   1406 N ND2 . ASN B  1 92 ? -19.73599 -10.13465 -23.24314 1.000 36.50026 ? 90  ASN C ND2 1 
ATOM   1407 N N   . LYS C  1 2  ? -12.35197 -23.37259 -40.08914 1.000 52.69405 ? 0   LYS E N   1 
ATOM   1408 C CA  . LYS C  1 2  ? -11.67886 -22.34497 -40.87525 1.000 57.25993 ? 0   LYS E CA  1 
ATOM   1409 C C   . LYS C  1 2  ? -10.92545 -21.38284 -39.95525 1.000 58.96887 ? 0   LYS E C   1 
ATOM   1410 O O   . LYS C  1 2  ? -10.53017 -21.75479 -38.84912 1.000 63.57849 ? 0   LYS E O   1 
ATOM   1411 C CB  . LYS C  1 2  ? -12.68992 -21.58691 -41.74295 1.000 47.90103 ? 0   LYS E CB  1 
ATOM   1412 C CG  . LYS C  1 2  ? -13.50938 -22.47353 -42.68417 1.000 46.26162 ? 0   LYS E CG  1 
ATOM   1413 C CD  . LYS C  1 2  ? -12.99935 -22.39924 -44.12172 1.000 41.17088 ? 0   LYS E CD  1 
ATOM   1414 C CE  . LYS C  1 2  ? -13.74629 -23.35844 -45.05090 1.000 30.41651 ? 0   LYS E CE  1 
ATOM   1415 N NZ  . LYS C  1 2  ? -15.11922 -22.89470 -45.40702 1.000 35.35055 ? 0   LYS E NZ  1 
ATOM   1416 N N   . ALA C  1 3  ? -10.72571 -20.14766 -40.41281 1.000 49.10365 ? 1   ALA E N   1 
ATOM   1417 C CA  . ALA C  1 3  ? -10.01887 -19.14549 -39.62378 1.000 50.85936 ? 1   ALA E CA  1 
ATOM   1418 C C   . ALA C  1 3  ? -10.51720 -17.76204 -40.01303 1.000 44.63904 ? 1   ALA E C   1 
ATOM   1419 O O   . ALA C  1 3  ? -10.50714 -17.40992 -41.19622 1.000 38.98733 ? 1   ALA E O   1 
ATOM   1420 C CB  . ALA C  1 3  ? -8.50482  -19.23866 -39.84728 1.000 48.38791 ? 1   ALA E CB  1 
ATOM   1421 N N   A SER C  1 4  ? -10.95958 -16.98874 -39.02353 0.642 35.32991 ? 2   SER E N   1 
ATOM   1422 N N   B SER C  1 4  ? -10.93210 -16.98366 -39.01526 0.358 35.21839 ? 2   SER E N   1 
ATOM   1423 C CA  A SER C  1 4  ? -11.47191 -15.64827 -39.26863 0.642 28.28889 ? 2   SER E CA  1 
ATOM   1424 C CA  B SER C  1 4  ? -11.46336 -15.64539 -39.23277 0.358 28.30962 ? 2   SER E CA  1 
ATOM   1425 C C   A SER C  1 4  ? -10.35016 -14.62397 -39.15204 0.642 25.92881 ? 2   SER E C   1 
ATOM   1426 C C   B SER C  1 4  ? -10.34092 -14.61959 -39.14647 0.358 25.93490 ? 2   SER E C   1 
ATOM   1427 O O   A SER C  1 4  ? -9.53640  -14.67299 -38.22355 0.642 28.88526 ? 2   SER E O   1 
ATOM   1428 O O   B SER C  1 4  ? -9.51979  -14.66249 -38.22329 0.358 28.84655 ? 2   SER E O   1 
ATOM   1429 C CB  A SER C  1 4  ? -12.59337 -15.30190 -38.28517 0.642 31.32223 ? 2   SER E CB  1 
ATOM   1430 C CB  B SER C  1 4  ? -12.53169 -15.32887 -38.18550 0.358 31.11253 ? 2   SER E CB  1 
ATOM   1431 O OG  A SER C  1 4  ? -13.80691 -15.96663 -38.60610 0.642 17.48279 ? 2   SER E OG  1 
ATOM   1432 O OG  B SER C  1 4  ? -12.78993 -13.93619 -38.11726 0.358 22.30949 ? 2   SER E OG  1 
ATOM   1433 N N   . VAL C  1 5  ? -10.30564 -13.70208 -40.11435 1.000 15.89238 ? 3   VAL E N   1 
ATOM   1434 C CA  . VAL C  1 5  ? -9.33813  -12.61456 -40.06702 1.000 12.17432 ? 3   VAL E CA  1 
ATOM   1435 C C   . VAL C  1 5  ? -9.66868  -11.67153 -38.91396 1.000 12.17827 ? 3   VAL E C   1 
ATOM   1436 O O   . VAL C  1 5  ? -10.76436 -11.69525 -38.33956 1.000 14.31451 ? 3   VAL E O   1 
ATOM   1437 C CB  . VAL C  1 5  ? -9.30425  -11.86616 -41.40986 1.000 11.60110 ? 3   VAL E CB  1 
ATOM   1438 C CG1 . VAL C  1 5  ? -8.97622  -12.82653 -42.54000 1.000 15.71905 ? 3   VAL E CG1 1 
ATOM   1439 C CG2 . VAL C  1 5  ? -10.63902 -11.15092 -41.66463 1.000 14.64925 ? 3   VAL E CG2 1 
ATOM   1440 N N   . GLN C  1 6  ? -8.69983  -10.83455 -38.56186 1.000 11.31172 ? 4   GLN E N   1 
ATOM   1441 C CA  . GLN C  1 6  ? -8.86178  -9.86256  -37.49273 1.000 10.97650 ? 4   GLN E CA  1 
ATOM   1442 C C   . GLN C  1 6  ? -8.44765  -8.50025  -38.01781 1.000 9.30106  ? 4   GLN E C   1 
ATOM   1443 O O   . GLN C  1 6  ? -7.49281  -8.39505  -38.79485 1.000 11.85290 ? 4   GLN E O   1 
ATOM   1444 C CB  . GLN C  1 6  ? -7.99235  -10.23692 -36.29813 1.000 11.62463 ? 4   GLN E CB  1 
ATOM   1445 C CG  . GLN C  1 6  ? -8.29346  -11.62112 -35.76649 1.000 15.69997 ? 4   GLN E CG  1 
ATOM   1446 C CD  . GLN C  1 6  ? -7.70932  -11.85793 -34.39355 1.000 28.29369 ? 4   GLN E CD  1 
ATOM   1447 O OE1 . GLN C  1 6  ? -7.04821  -10.98723 -33.83182 1.000 21.31702 ? 4   GLN E OE1 1 
ATOM   1448 N NE2 . GLN C  1 6  ? -7.95674  -13.04076 -33.83904 1.000 34.32288 ? 4   GLN E NE2 1 
ATOM   1449 N N   . THR C  1 7  ? -9.16669  -7.45552  -37.61229 1.000 8.63090  ? 5   THR E N   1 
ATOM   1450 C CA  . THR C  1 7  ? -8.89656  -6.13009  -38.14392 1.000 7.55159  ? 5   THR E CA  1 
ATOM   1451 C C   . THR C  1 7  ? -8.67475  -5.10842  -37.03888 1.000 7.30721  ? 5   THR E C   1 
ATOM   1452 O O   . THR C  1 7  ? -9.01284  -5.31880  -35.86775 1.000 8.47082  ? 5   THR E O   1 
ATOM   1453 C CB  . THR C  1 7  ? -10.00233 -5.61707  -39.08975 1.000 8.19876  ? 5   THR E CB  1 
ATOM   1454 O OG1 . THR C  1 7  ? -11.19327 -5.32932  -38.34584 1.000 8.82865  ? 5   THR E OG1 1 
ATOM   1455 C CG2 . THR C  1 7  ? -10.30715 -6.61822  -40.20245 1.000 9.27382  ? 5   THR E CG2 1 
ATOM   1456 N N   . ALA C  1 8  ? -8.10824  -3.98138  -37.45964 1.000 7.45720  ? 6   ALA E N   1 
ATOM   1457 C CA  . ALA C  1 8  ? -7.94442  -2.78338  -36.65621 1.000 7.47474  ? 6   ALA E CA  1 
ATOM   1458 C C   . ALA C  1 8  ? -8.17720  -1.60960  -37.58902 1.000 6.19830  ? 6   ALA E C   1 
ATOM   1459 O O   . ALA C  1 8  ? -7.84911  -1.68548  -38.77507 1.000 8.20262  ? 6   ALA E O   1 
ATOM   1460 C CB  . ALA C  1 8  ? -6.53065  -2.70707  -36.07037 1.000 8.92079  ? 6   ALA E CB  1 
ATOM   1461 N N   . ALA C  1 9  ? -8.73501  -0.52460  -37.06565 1.000 6.36009  ? 7   ALA E N   1 
ATOM   1462 C CA  . ALA C  1 9  ? -9.09015  0.60723   -37.91025 1.000 6.86279  ? 7   ALA E CA  1 
ATOM   1463 C C   . ALA C  1 9  ? -8.76600  1.92170   -37.21740 1.000 6.43522  ? 7   ALA E C   1 
ATOM   1464 O O   . ALA C  1 9  ? -8.85705  2.03846   -35.99120 1.000 7.32360  ? 7   ALA E O   1 
ATOM   1465 C CB  . ALA C  1 9  ? -10.57608 0.58746   -38.26964 1.000 8.58814  ? 7   ALA E CB  1 
ATOM   1466 N N   . THR C  1 10 ? -8.40711  2.92109   -38.02410 1.000 6.58764  ? 8   THR E N   1 
ATOM   1467 C CA  . THR C  1 10 ? -8.19634  4.27616   -37.54408 1.000 6.88570  ? 8   THR E CA  1 
ATOM   1468 C C   . THR C  1 10 ? -8.67998  5.24493   -38.61428 1.000 7.00467  ? 8   THR E C   1 
ATOM   1469 O O   . THR C  1 10 ? -8.85546  4.87356   -39.77819 1.000 7.65694  ? 8   THR E O   1 
ATOM   1470 C CB  . THR C  1 10 ? -6.72755  4.51741   -37.14145 1.000 7.96653  ? 8   THR E CB  1 
ATOM   1471 O OG1 . THR C  1 10 ? -6.62662  5.71220   -36.35907 1.000 9.01428  ? 8   THR E OG1 1 
ATOM   1472 C CG2 . THR C  1 10 ? -5.82657  4.64676   -38.36509 1.000 8.77206  ? 8   THR E CG2 1 
ATOM   1473 N N   . SER C  1 11 ? -8.93425  6.48471   -38.20612 1.000 7.19080  ? 9   SER E N   1 
ATOM   1474 C CA  . SER C  1 11 ? -9.45033  7.48615   -39.12630 1.000 7.09915  ? 9   SER E CA  1 
ATOM   1475 C C   . SER C  1 11 ? -9.02189  8.86649   -38.65567 1.000 7.79871  ? 9   SER E C   1 
ATOM   1476 O O   . SER C  1 11 ? -8.69127  9.06236   -37.48545 1.000 8.34597  ? 9   SER E O   1 
ATOM   1477 C CB  . SER C  1 11 ? -10.97711 7.41885   -39.23434 1.000 7.96416  ? 9   SER E CB  1 
ATOM   1478 O OG  . SER C  1 11 ? -11.57876 7.66652   -37.97518 1.000 8.28506  ? 9   SER E OG  1 
ATOM   1479 N N   . TRP C  1 12 ? -9.03204  9.83180   -39.57496 1.000 7.03754  ? 10  TRP E N   1 
ATOM   1480 C CA  . TRP C  1 12 ? -8.67556  11.19766  -39.21104 1.000 8.95064  ? 10  TRP E CA  1 
ATOM   1481 C C   . TRP C  1 12 ? -9.34437  12.20833  -40.12817 1.000 8.83048  ? 10  TRP E C   1 
ATOM   1482 O O   . TRP C  1 12 ? -9.71647  11.90896  -41.26514 1.000 9.45392  ? 10  TRP E O   1 
ATOM   1483 C CB  . TRP C  1 12 ? -7.16217  11.41374  -39.18526 1.000 8.67637  ? 10  TRP E CB  1 
ATOM   1484 C CG  . TRP C  1 12 ? -6.47194  11.25930  -40.51328 1.000 8.11966  ? 10  TRP E CG  1 
ATOM   1485 C CD1 . TRP C  1 12 ? -6.20985  12.24415  -41.42167 1.000 8.93950  ? 10  TRP E CD1 1 
ATOM   1486 C CD2 . TRP C  1 12 ? -5.92434  10.05224  -41.06278 1.000 7.63786  ? 10  TRP E CD2 1 
ATOM   1487 N NE1 . TRP C  1 12 ? -5.54081  11.72209  -42.50798 1.000 9.07654  ? 10  TRP E NE1 1 
ATOM   1488 C CE2 . TRP C  1 12 ? -5.34564  10.38029  -42.30824 1.000 7.99673  ? 10  TRP E CE2 1 
ATOM   1489 C CE3 . TRP C  1 12 ? -5.86415  8.72519   -40.62066 1.000 8.70741  ? 10  TRP E CE3 1 
ATOM   1490 C CZ2 . TRP C  1 12 ? -4.71938  9.42798   -43.11689 1.000 8.80162  ? 10  TRP E CZ2 1 
ATOM   1491 C CZ3 . TRP C  1 12 ? -5.23482  7.77776   -41.42816 1.000 8.58375  ? 10  TRP E CZ3 1 
ATOM   1492 C CH2 . TRP C  1 12 ? -4.67619  8.13890   -42.66201 1.000 8.79442  ? 10  TRP E CH2 1 
ATOM   1493 N N   . GLY C  1 13 ? -9.46840  13.42851  -39.61217 1.000 10.02931 ? 11  GLY E N   1 
ATOM   1494 C CA  . GLY C  1 13 ? -10.06621 14.50608  -40.36250 1.000 14.04711 ? 11  GLY E CA  1 
ATOM   1495 C C   . GLY C  1 13 ? -11.56633 14.34146  -40.48461 1.000 13.74822 ? 11  GLY E C   1 
ATOM   1496 O O   . GLY C  1 13 ? -12.19828 13.52572  -39.81578 1.000 14.58545 ? 11  GLY E O   1 
ATOM   1497 N N   . THR C  1 14 ? -12.13631 15.14372  -41.38155 1.000 13.31483 ? 12  THR E N   1 
ATOM   1498 C CA  . THR C  1 14 ? -13.57858 15.18736  -41.56064 1.000 16.80623 ? 12  THR E CA  1 
ATOM   1499 C C   . THR C  1 14 ? -14.04795 14.57239  -42.86871 1.000 13.77989 ? 12  THR E C   1 
ATOM   1500 O O   . THR C  1 14 ? -15.25703 14.39998  -43.05074 1.000 17.36425 ? 12  THR E O   1 
ATOM   1501 C CB  . THR C  1 14 ? -14.08366 16.63579  -41.47131 1.000 18.35129 ? 12  THR E CB  1 
ATOM   1502 O OG1 . THR C  1 14 ? -13.40281 17.43655  -42.44625 1.000 19.00067 ? 12  THR E OG1 1 
ATOM   1503 C CG2 . THR C  1 14 ? -13.82782 17.20631  -40.08098 1.000 19.30545 ? 12  THR E CG2 1 
ATOM   1504 N N   . VAL C  1 15 ? -13.13350 14.24260  -43.78204 1.000 13.40873 ? 13  VAL E N   1 
ATOM   1505 C CA  . VAL C  1 15 ? -13.53953 13.62050  -45.04278 1.000 12.90051 ? 13  VAL E CA  1 
ATOM   1506 C C   . VAL C  1 15 ? -14.25347 12.28747  -44.83642 1.000 12.07413 ? 13  VAL E C   1 
ATOM   1507 O O   . VAL C  1 15 ? -15.34549 12.10519  -45.39504 1.000 13.01705 ? 13  VAL E O   1 
ATOM   1508 C CB  . VAL C  1 15 ? -12.35148 13.55296  -46.01966 1.000 12.93802 ? 13  VAL E CB  1 
ATOM   1509 C CG1 . VAL C  1 15 ? -12.77243 12.86488  -47.30861 1.000 15.58218 ? 13  VAL E CG1 1 
ATOM   1510 C CG2 . VAL C  1 15 ? -11.79483 14.94591  -46.28940 1.000 13.92501 ? 13  VAL E CG2 1 
ATOM   1511 N N   . PRO C  1 16 ? -13.70524 11.32128  -44.08325 1.000 10.73774 ? 14  PRO E N   1 
ATOM   1512 C CA  . PRO C  1 16 ? -12.39892 11.28029  -43.43866 1.000 9.85286  ? 14  PRO E CA  1 
ATOM   1513 C C   . PRO C  1 16 ? -11.43271 10.48486  -44.29628 1.000 8.89524  ? 14  PRO E C   1 
ATOM   1514 O O   . PRO C  1 16 ? -11.78369 9.97889   -45.36711 1.000 9.87982  ? 14  PRO E O   1 
ATOM   1515 C CB  . PRO C  1 16 ? -12.70007 10.47162  -42.17988 1.000 10.61302 ? 14  PRO E CB  1 
ATOM   1516 C CG  . PRO C  1 16 ? -13.61693 9.40396   -42.72051 1.000 10.41656 ? 14  PRO E CG  1 
ATOM   1517 C CD  . PRO C  1 16 ? -14.48101 10.11271  -43.75173 1.000 11.15460 ? 14  PRO E CD  1 
ATOM   1518 N N   . SER C  1 17 ? -10.19872 10.35733  -43.82516 1.000 8.17295  ? 15  SER E N   1 
ATOM   1519 C CA  . SER C  1 17 ? -9.35068  9.25606   -44.24057 1.000 7.78449  ? 15  SER E CA  1 
ATOM   1520 C C   . SER C  1 17 ? -9.53196  8.11961   -43.24564 1.000 7.60316  ? 15  SER E C   1 
ATOM   1521 O O   . SER C  1 17 ? -9.67074  8.35361   -42.04182 1.000 8.33678  ? 15  SER E O   1 
ATOM   1522 C CB  . SER C  1 17 ? -7.88286  9.67207   -44.28513 1.000 9.03295  ? 15  SER E CB  1 
ATOM   1523 O OG  . SER C  1 17 ? -7.61178  10.50240  -45.40146 1.000 10.31284 ? 15  SER E OG  1 
ATOM   1524 N N   . ILE C  1 18 ? -9.53315  6.89034   -43.75893 1.000 6.96871  ? 16  ILE E N   1 
ATOM   1525 C CA  . ILE C  1 18 ? -9.63581  5.67936   -42.95309 1.000 6.20479  ? 16  ILE E CA  1 
ATOM   1526 C C   . ILE C  1 18 ? -8.53179  4.72614   -43.38249 1.000 6.56600  ? 16  ILE E C   1 
ATOM   1527 O O   . ILE C  1 18 ? -8.21198  4.64100   -44.57545 1.000 6.47421  ? 16  ILE E O   1 
ATOM   1528 C CB  . ILE C  1 18 ? -11.00658 4.97751   -43.11620 1.000 7.20224  ? 16  ILE E CB  1 
ATOM   1529 C CG1 . ILE C  1 18 ? -12.17311 5.95716   -42.99138 1.000 8.47953  ? 16  ILE E CG1 1 
ATOM   1530 C CG2 . ILE C  1 18 ? -11.15249 3.84746   -42.10331 1.000 8.24159  ? 16  ILE E CG2 1 
ATOM   1531 C CD1 . ILE C  1 18 ? -13.51572 5.38200   -43.41304 1.000 8.86678  ? 16  ILE E CD1 1 
ATOM   1532 N N   . ARG C  1 19 ? -7.96011  4.00196   -42.42009 1.000 6.12909  ? 17  ARG E N   1 
ATOM   1533 C CA  . ARG C  1 19 ? -7.04917  2.90531   -42.71349 1.000 6.50553  ? 17  ARG E CA  1 
ATOM   1534 C C   . ARG C  1 19 ? -7.51594  1.69145   -41.92887 1.000 5.92384  ? 17  ARG E C   1 
ATOM   1535 O O   . ARG C  1 19 ? -7.75983  1.78842   -40.71988 1.000 7.15801  ? 17  ARG E O   1 
ATOM   1536 C CB  . ARG C  1 19 ? -5.59458  3.24188   -42.36084 1.000 7.32989  ? 17  ARG E CB  1 
ATOM   1537 C CG  . ARG C  1 19 ? -5.04150  4.46061   -43.08073 1.000 6.72969  ? 17  ARG E CG  1 
ATOM   1538 C CD  . ARG C  1 19 ? -4.84996  4.18699   -44.57289 1.000 6.70934  ? 17  ARG E CD  1 
ATOM   1539 N NE  . ARG C  1 19 ? -4.24936  5.31251   -45.28676 1.000 7.33936  ? 17  ARG E NE  1 
ATOM   1540 C CZ  . ARG C  1 19 ? -4.92368  6.30881   -45.84767 1.000 7.33256  ? 17  ARG E CZ  1 
ATOM   1541 N NH1 . ARG C  1 19 ? -6.24611  6.37309   -45.80087 1.000 7.58105  ? 17  ARG E NH1 1 
ATOM   1542 N NH2 . ARG C  1 19 ? -4.25296  7.25942   -46.49632 1.000 8.34087  ? 17  ARG E NH2 1 
ATOM   1543 N N   . VAL C  1 20 ? -7.66136  0.56344   -42.61763 1.000 6.39491  ? 18  VAL E N   1 
ATOM   1544 C CA  . VAL C  1 20 ? -8.09762  -0.68664  -42.01537 1.000 6.56655  ? 18  VAL E CA  1 
ATOM   1545 C C   . VAL C  1 20 ? -7.00580  -1.71557  -42.24065 1.000 6.08344  ? 18  VAL E C   1 
ATOM   1546 O O   . VAL C  1 20 ? -6.61444  -1.97646  -43.38820 1.000 6.34931  ? 18  VAL E O   1 
ATOM   1547 C CB  . VAL C  1 20 ? -9.42331  -1.17832  -42.61146 1.000 6.63154  ? 18  VAL E CB  1 
ATOM   1548 C CG1 . VAL C  1 20 ? -9.84202  -2.50274  -41.98366 1.000 8.04290  ? 18  VAL E CG1 1 
ATOM   1549 C CG2 . VAL C  1 20 ? -10.51648 -0.12946  -42.45082 1.000 8.24285  ? 18  VAL E CG2 1 
ATOM   1550 N N   . TYR C  1 21 ? -6.53123  -2.30728  -41.15213 1.000 6.23112  ? 19  TYR E N   1 
ATOM   1551 C CA  . TYR C  1 21 ? -5.47414  -3.30807  -41.17528 1.000 6.65023  ? 19  TYR E CA  1 
ATOM   1552 C C   . TYR C  1 21 ? -6.09697  -4.66939  -40.92907 1.000 7.25908  ? 19  TYR E C   1 
ATOM   1553 O O   . TYR C  1 21 ? -6.91507  -4.81383  -40.01885 1.000 7.63187  ? 19  TYR E O   1 
ATOM   1554 C CB  . TYR C  1 21 ? -4.42524  -2.98238  -40.09488 1.000 6.94549  ? 19  TYR E CB  1 
ATOM   1555 C CG  . TYR C  1 21 ? -3.85474  -1.61724  -40.35063 1.000 6.61602  ? 19  TYR E CG  1 
ATOM   1556 C CD1 . TYR C  1 21 ? -4.47473  -0.48085  -39.84686 1.000 7.71993  ? 19  TYR E CD1 1 
ATOM   1557 C CD2 . TYR C  1 21 ? -2.77254  -1.44853  -41.19373 1.000 7.75399  ? 19  TYR E CD2 1 
ATOM   1558 C CE1 . TYR C  1 21 ? -4.00738  0.77622   -40.14554 1.000 6.83561  ? 19  TYR E CE1 1 
ATOM   1559 C CE2 . TYR C  1 21 ? -2.30193  -0.19503  -41.49806 1.000 7.09250  ? 19  TYR E CE2 1 
ATOM   1560 C CZ  . TYR C  1 21 ? -2.92225  0.91865   -40.97065 1.000 6.79617  ? 19  TYR E CZ  1 
ATOM   1561 O OH  . TYR C  1 21 ? -2.47904  2.18110   -41.29926 1.000 7.70160  ? 19  TYR E OH  1 
ATOM   1562 N N   . THR C  1 22 ? -5.72050  -5.66199  -41.73413 1.000 6.79018  ? 20  THR E N   1 
ATOM   1563 C CA  . THR C  1 22 ? -6.26924  -7.00898  -41.60508 1.000 7.41217  ? 20  THR E CA  1 
ATOM   1564 C C   . THR C  1 22 ? -5.14038  -8.00538  -41.40823 1.000 7.16810  ? 20  THR E C   1 
ATOM   1565 O O   . THR C  1 22 ? -4.24164  -8.09236  -42.24808 1.000 8.10020  ? 20  THR E O   1 
ATOM   1566 C CB  . THR C  1 22 ? -7.08838  -7.40641  -42.83216 1.000 7.70490  ? 20  THR E CB  1 
ATOM   1567 O OG1 . THR C  1 22 ? -8.16014  -6.48222  -43.00089 1.000 8.87353  ? 20  THR E OG1 1 
ATOM   1568 C CG2 . THR C  1 22 ? -7.67453  -8.80845  -42.65644 1.000 9.55769  ? 20  THR E CG2 1 
ATOM   1569 N N   . ALA C  1 23 ? -5.19742  -8.74712  -40.30264 1.000 8.43143  ? 21  ALA E N   1 
ATOM   1570 C CA  . ALA C  1 23 ? -4.31387  -9.87828  -40.05682 1.000 8.49033  ? 21  ALA E CA  1 
ATOM   1571 C C   . ALA C  1 23 ? -4.98424  -11.11704 -40.63194 1.000 9.35838  ? 21  ALA E C   1 
ATOM   1572 O O   . ALA C  1 23 ? -6.07236  -11.50617 -40.19583 1.000 10.95047 ? 21  ALA E O   1 
ATOM   1573 C CB  . ALA C  1 23 ? -4.04899  -10.04042 -38.55977 1.000 11.44413 ? 21  ALA E CB  1 
ATOM   1574 N N   . ASN C  1 24 ? -4.36239  -11.69739 -41.65025 1.000 9.86516  ? 22  ASN E N   1 
ATOM   1575 C CA  . ASN C  1 24 ? -4.91818  -12.83577 -42.36744 1.000 13.11848 ? 22  ASN E CA  1 
ATOM   1576 C C   . ASN C  1 24 ? -3.78744  -13.81595 -42.59856 1.000 11.01314 ? 22  ASN E C   1 
ATOM   1577 O O   . ASN C  1 24 ? -2.82215  -13.48933 -43.28908 1.000 11.61942 ? 22  ASN E O   1 
ATOM   1578 C CB  . ASN C  1 24 ? -5.51457  -12.39348 -43.70820 1.000 13.76104 ? 22  ASN E CB  1 
ATOM   1579 C CG  . ASN C  1 24 ? -6.14604  -13.54421 -44.47393 1.000 16.52442 ? 22  ASN E CG  1 
ATOM   1580 O OD1 . ASN C  1 24 ? -6.33394  -14.63317 -43.93370 1.000 21.25192 ? 22  ASN E OD1 1 
ATOM   1581 N ND2 . ASN C  1 24 ? -6.49820  -13.29843 -45.72793 1.000 20.78228 ? 22  ASN E ND2 1 
ATOM   1582 N N   . ASN C  1 25 ? -3.90029  -15.00072 -42.00276 1.000 13.82356 ? 23  ASN E N   1 
ATOM   1583 C CA  . ASN C  1 25 ? -2.91786  -16.06539 -42.19383 1.000 15.47424 ? 23  ASN E CA  1 
ATOM   1584 C C   . ASN C  1 25 ? -1.48790  -15.58608 -41.94657 1.000 15.00187 ? 23  ASN E C   1 
ATOM   1585 O O   . ASN C  1 25 ? -0.56755  -15.88696 -42.70811 1.000 15.76630 ? 23  ASN E O   1 
ATOM   1586 C CB  . ASN C  1 25 ? -3.05922  -16.72981 -43.56595 1.000 21.38027 ? 23  ASN E CB  1 
ATOM   1587 C CG  . ASN C  1 25 ? -4.00684  -17.91265 -43.54650 1.000 26.59034 ? 23  ASN E CG  1 
ATOM   1588 O OD1 . ASN C  1 25 ? -4.79948  -18.07780 -42.61772 1.000 33.02085 ? 23  ASN E OD1 1 
ATOM   1589 N ND2 . ASN C  1 25 ? -3.92199  -18.75040 -44.57175 1.000 36.08638 ? 23  ASN E ND2 1 
ATOM   1590 N N   . GLY C  1 26 ? -1.30128  -14.81956 -40.87464 1.000 13.88273 ? 24  GLY E N   1 
ATOM   1591 C CA  . GLY C  1 26 ? 0.02757   -14.43649 -40.44774 1.000 14.15537 ? 24  GLY E CA  1 
ATOM   1592 C C   . GLY C  1 26 ? 0.59059   -13.18310 -41.08267 1.000 10.83036 ? 24  GLY E C   1 
ATOM   1593 O O   . GLY C  1 26 ? 1.73475   -12.81928 -40.77809 1.000 12.02300 ? 24  GLY E O   1 
ATOM   1594 N N   . LYS C  1 27 ? -0.16179  -12.51571 -41.95817 1.000 10.57233 ? 25  LYS E N   1 
ATOM   1595 C CA  . LYS C  1 27 ? 0.28504   -11.29232 -42.60507 1.000 10.98549 ? 25  LYS E CA  1 
ATOM   1596 C C   . LYS C  1 27 ? -0.74501  -10.19611 -42.38582 1.000 8.94062  ? 25  LYS E C   1 
ATOM   1597 O O   . LYS C  1 27 ? -1.95272  -10.44626 -42.45736 1.000 10.88495 ? 25  LYS E O   1 
ATOM   1598 C CB  . LYS C  1 27 ? 0.45969   -11.50360 -44.11183 1.000 13.67648 ? 25  LYS E CB  1 
ATOM   1599 C CG  . LYS C  1 27 ? 1.50859   -12.54263 -44.46407 1.000 17.64300 ? 25  LYS E CG  1 
ATOM   1600 C CD  . LYS C  1 27 ? 1.55959   -12.79980 -45.96205 1.000 38.33736 ? 25  LYS E CD  1 
ATOM   1601 C CE  . LYS C  1 27 ? 1.68425   -11.50082 -46.74369 1.000 52.90117 ? 25  LYS E CE  1 
ATOM   1602 N NZ  . LYS C  1 27 ? 2.38810   -11.70397 -48.04151 1.000 57.86644 ? 25  LYS E NZ  1 
ATOM   1603 N N   . ILE C  1 28 ? -0.26446  -8.97968  -42.13984 1.000 8.18591  ? 26  ILE E N   1 
ATOM   1604 C CA  . ILE C  1 28 ? -1.12190  -7.81220  -41.97966 1.000 7.29545  ? 26  ILE E CA  1 
ATOM   1605 C C   . ILE C  1 28 ? -0.99008  -6.94850  -43.22331 1.000 8.30399  ? 26  ILE E C   1 
ATOM   1606 O O   . ILE C  1 28 ? 0.11916   -6.55068  -43.60165 1.000 9.16280  ? 26  ILE E O   1 
ATOM   1607 C CB  . ILE C  1 28 ? -0.77097  -7.00741  -40.72241 1.000 7.48214  ? 26  ILE E CB  1 
ATOM   1608 C CG1 . ILE C  1 28 ? -0.86114  -7.88624  -39.47831 1.000 9.28020  ? 26  ILE E CG1 1 
ATOM   1609 C CG2 . ILE C  1 28 ? -1.69202  -5.79711  -40.60884 1.000 8.98220  ? 26  ILE E CG2 1 
ATOM   1610 C CD1 . ILE C  1 28 ? -0.21432  -7.25847  -38.26768 1.000 10.73711 ? 26  ILE E CD1 1 
ATOM   1611 N N   . THR C  1 29 ? -2.12297  -6.65889  -43.85503 1.000 7.38074  ? 27  THR E N   1 
ATOM   1612 C CA  . THR C  1 29 ? -2.20317  -5.76319  -44.99630 1.000 7.50420  ? 27  THR E CA  1 
ATOM   1613 C C   . THR C  1 29 ? -3.15935  -4.62114  -44.67758 1.000 6.65436  ? 27  THR E C   1 
ATOM   1614 O O   . THR C  1 29 ? -3.80199  -4.59741  -43.62887 1.000 7.66002  ? 27  THR E O   1 
ATOM   1615 C CB  . THR C  1 29 ? -2.62365  -6.52257  -46.25755 1.000 10.97517 ? 27  THR E CB  1 
ATOM   1616 O OG1 . THR C  1 29 ? -3.87124  -7.17885  -46.01931 1.000 12.83645 ? 27  THR E OG1 1 
ATOM   1617 C CG2 . THR C  1 29 ? -1.55756  -7.56044  -46.62490 1.000 12.41280 ? 27  THR E CG2 1 
ATOM   1618 N N   . GLU C  1 30 ? -3.23857  -3.66469  -45.59247 1.000 6.82893  ? 28  GLU E N   1 
ATOM   1619 C CA  . GLU C  1 30 ? -3.87125  -2.38537  -45.31225 1.000 6.66152  ? 28  GLU E CA  1 
ATOM   1620 C C   . GLU C  1 30 ? -4.74672  -1.96504  -46.47991 1.000 6.50453  ? 28  GLU E C   1 
ATOM   1621 O O   . GLU C  1 30 ? -4.33206  -2.05031  -47.63789 1.000 7.03523  ? 28  GLU E O   1 
ATOM   1622 C CB  . GLU C  1 30 ? -2.78270  -1.32547  -45.10319 1.000 7.36146  ? 28  GLU E CB  1 
ATOM   1623 C CG  . GLU C  1 30 ? -3.27360  0.07551   -44.82818 1.000 7.30355  ? 28  GLU E CG  1 
ATOM   1624 C CD  . GLU C  1 30 ? -2.14285  1.08722   -44.87846 1.000 7.51031  ? 28  GLU E CD  1 
ATOM   1625 O OE1 . GLU C  1 30 ? -1.32176  0.98564   -45.81398 1.000 7.89593  ? 28  GLU E OE1 1 
ATOM   1626 O OE2 . GLU C  1 30 ? -2.07360  1.97291   -43.99037 1.000 7.79497  ? 28  GLU E OE2 1 
ATOM   1627 N N   . ARG C  1 31 ? -5.94816  -1.48563  -46.15799 1.000 6.42937  ? 29  ARG E N   1 
ATOM   1628 C CA  . ARG C  1 31 ? -6.85524  -0.86508  -47.11257 1.000 6.58100  ? 29  ARG E CA  1 
ATOM   1629 C C   . ARG C  1 31 ? -7.11483  0.56715   -46.67512 1.000 6.28142  ? 29  ARG E C   1 
ATOM   1630 O O   . ARG C  1 31 ? -7.19463  0.85833   -45.47491 1.000 6.84519  ? 29  ARG E O   1 
ATOM   1631 C CB  . ARG C  1 31 ? -8.16186  -1.66237  -47.24397 1.000 7.41914  ? 29  ARG E CB  1 
ATOM   1632 C CG  . ARG C  1 31 ? -7.95459  -3.04690  -47.84315 1.000 7.97197  ? 29  ARG E CG  1 
ATOM   1633 C CD  . ARG C  1 31 ? -7.76383  -2.98883  -49.34753 1.000 8.61352  ? 29  ARG E CD  1 
ATOM   1634 N NE  . ARG C  1 31 ? -9.05196  -2.88117  -50.02345 1.000 8.27860  ? 29  ARG E NE  1 
ATOM   1635 C CZ  . ARG C  1 31 ? -9.19239  -2.69455  -51.32878 1.000 8.95301  ? 29  ARG E CZ  1 
ATOM   1636 N NH1 . ARG C  1 31 ? -8.14221  -2.52783  -52.12118 1.000 9.61338  ? 29  ARG E NH1 1 
ATOM   1637 N NH2 . ARG C  1 31 ? -10.41747 -2.66970  -51.85299 1.000 9.26231  ? 29  ARG E NH2 1 
ATOM   1638 N N   . CYS C  1 32 ? -7.26075  1.45748   -47.65447 1.000 6.36110  ? 30  CYS E N   1 
ATOM   1639 C CA  . CYS C  1 32 ? -7.23813  2.89118   -47.43089 1.000 6.74032  ? 30  CYS E CA  1 
ATOM   1640 C C   . CYS C  1 32 ? -8.42269  3.55533   -48.10605 1.000 6.57940  ? 30  CYS E C   1 
ATOM   1641 O O   . CYS C  1 32 ? -8.79831  3.18625   -49.22532 1.000 7.22078  ? 30  CYS E O   1 
ATOM   1642 C CB  . CYS C  1 32 ? -5.99469  3.50353   -48.06434 1.000 7.07508  ? 30  CYS E CB  1 
ATOM   1643 S SG  . CYS C  1 32 ? -4.42859  2.69814   -47.63951 1.000 7.45316  ? 30  CYS E SG  1 
ATOM   1644 N N   . TRP C  1 33 ? -8.95310  4.58431   -47.44940 1.000 6.71456  ? 31  TRP E N   1 
ATOM   1645 C CA  . TRP C  1 33 ? -10.01726 5.41883   -47.98583 1.000 7.10363  ? 31  TRP E CA  1 
ATOM   1646 C C   . TRP C  1 33 ? -9.66151  6.86739   -47.70252 1.000 7.45074  ? 31  TRP E C   1 
ATOM   1647 O O   . TRP C  1 33 ? -9.30542  7.20254   -46.56903 1.000 8.02992  ? 31  TRP E O   1 
ATOM   1648 C CB  . TRP C  1 33 ? -11.32800 5.09684   -47.25231 1.000 8.03695  ? 31  TRP E CB  1 
ATOM   1649 C CG  . TRP C  1 33 ? -12.46538 6.02134   -47.57742 1.000 8.85632  ? 31  TRP E CG  1 
ATOM   1650 C CD1 . TRP C  1 33 ? -12.80689 7.18483   -46.93394 1.000 9.19482  ? 31  TRP E CD1 1 
ATOM   1651 C CD2 . TRP C  1 33 ? -13.42253 5.84793   -48.62147 1.000 9.20160  ? 31  TRP E CD2 1 
ATOM   1652 N NE1 . TRP C  1 33 ? -13.91641 7.74475   -47.52929 1.000 9.55239  ? 31  TRP E NE1 1 
ATOM   1653 C CE2 . TRP C  1 33 ? -14.31495 6.93965   -48.56489 1.000 9.19390  ? 31  TRP E CE2 1 
ATOM   1654 C CE3 . TRP C  1 33 ? -13.62119 4.86875   -49.59198 1.000 8.67869  ? 31  TRP E CE3 1 
ATOM   1655 C CZ2 . TRP C  1 33 ? -15.37643 7.08142   -49.45203 1.000 10.20636 ? 31  TRP E CZ2 1 
ATOM   1656 C CZ3 . TRP C  1 33 ? -14.68522 5.00840   -50.46482 1.000 10.20453 ? 31  TRP E CZ3 1 
ATOM   1657 C CH2 . TRP C  1 33 ? -15.54456 6.10940   -50.39477 1.000 10.29320 ? 31  TRP E CH2 1 
ATOM   1658 N N   . ASP C  1 34 ? -9.77904  7.73264   -48.71101 1.000 7.77599  ? 32  ASP E N   1 
ATOM   1659 C CA  . ASP C  1 34 ? -9.66260  9.16935   -48.47907 1.000 8.14939  ? 32  ASP E CA  1 
ATOM   1660 C C   . ASP C  1 34 ? -10.76859 9.92644   -49.19151 1.000 9.11084  ? 32  ASP E C   1 
ATOM   1661 O O   . ASP C  1 34 ? -10.60492 11.10376  -49.53192 1.000 12.42217 ? 32  ASP E O   1 
ATOM   1662 C CB  . ASP C  1 34 ? -8.29825  9.74067   -48.86971 1.000 10.19612 ? 32  ASP E CB  1 
ATOM   1663 C CG  . ASP C  1 34 ? -7.14550  8.84032   -48.49684 1.000 8.86320  ? 32  ASP E CG  1 
ATOM   1664 O OD1 . ASP C  1 34 ? -6.69168  8.84792   -47.33265 1.000 8.71364  ? 32  ASP E OD1 1 
ATOM   1665 O OD2 . ASP C  1 34 ? -6.67355  8.13234   -49.40099 1.000 9.83881  ? 32  ASP E OD2 1 
ATOM   1666 N N   . GLY C  1 35 ? -11.88781 9.26832   -49.43019 1.000 9.54530  ? 33  GLY E N   1 
ATOM   1667 C CA  . GLY C  1 35 ? -13.05028 9.90988   -50.00130 1.000 11.34117 ? 33  GLY E CA  1 
ATOM   1668 C C   . GLY C  1 35 ? -13.37742 9.49443   -51.41714 1.000 13.19095 ? 33  GLY E C   1 
ATOM   1669 O O   . GLY C  1 35 ? -14.44111 9.88167   -51.91826 1.000 16.64138 ? 33  GLY E O   1 
ATOM   1670 N N   . LYS C  1 36 ? -12.51800 8.72203   -52.08036 1.000 12.18852 ? 34  LYS E N   1 
ATOM   1671 C CA  . LYS C  1 36 ? -12.69892 8.42028   -53.50006 1.000 12.04533 ? 34  LYS E CA  1 
ATOM   1672 C C   . LYS C  1 36 ? -12.41311 6.95073   -53.80901 1.000 10.88358 ? 34  LYS E C   1 
ATOM   1673 O O   . LYS C  1 36 ? -11.80652 6.61853   -54.83181 1.000 13.02475 ? 34  LYS E O   1 
ATOM   1674 C CB  . LYS C  1 36 ? -11.88690 9.36675   -54.38776 1.000 15.13804 ? 34  LYS E CB  1 
ATOM   1675 C CG  . LYS C  1 36 ? -10.36974 9.30147   -54.22716 1.000 22.52335 ? 34  LYS E CG  1 
ATOM   1676 C CD  . LYS C  1 36 ? -9.67921  9.97439   -55.41284 1.000 26.35680 ? 34  LYS E CD  1 
ATOM   1677 C CE  . LYS C  1 36 ? -8.16489  9.85720   -55.33282 1.000 27.34506 ? 34  LYS E CE  1 
ATOM   1678 N NZ  . LYS C  1 36 ? -7.50807  10.25443  -56.61678 1.000 24.10289 ? 34  LYS E NZ  1 
ATOM   1679 N N   . GLY C  1 37 ? -12.85560 6.05325   -52.94799 1.000 10.52334 ? 35  GLY E N   1 
ATOM   1680 C CA  . GLY C  1 37 ? -12.72598 4.63215   -53.19160 1.000 8.79723  ? 35  GLY E CA  1 
ATOM   1681 C C   . GLY C  1 37 ? -11.67533 4.00130   -52.29388 1.000 7.80377  ? 35  GLY E C   1 
ATOM   1682 O O   . GLY C  1 37 ? -10.69836 4.64386   -51.88396 1.000 9.89041  ? 35  GLY E O   1 
ATOM   1683 N N   . TRP C  1 38 ? -11.86039 2.71771   -52.01302 1.000 7.39530  ? 36  TRP E N   1 
ATOM   1684 C CA  . TRP C  1 38 ? -10.88540 1.95737   -51.24594 1.000 7.39701  ? 36  TRP E CA  1 
ATOM   1685 C C   . TRP C  1 38 ? -9.76187  1.46000   -52.14344 1.000 7.27990  ? 36  TRP E C   1 
ATOM   1686 O O   . TRP C  1 38 ? -9.99086  1.05400   -53.28851 1.000 8.91859  ? 36  TRP E O   1 
ATOM   1687 C CB  . TRP C  1 38 ? -11.56117 0.76279   -50.57535 1.000 7.58415  ? 36  TRP E CB  1 
ATOM   1688 C CG  . TRP C  1 38 ? -12.45294 1.17300   -49.45340 1.000 7.16173  ? 36  TRP E CG  1 
ATOM   1689 C CD1 . TRP C  1 38 ? -13.79023 1.45776   -49.52332 1.000 6.89413  ? 36  TRP E CD1 1 
ATOM   1690 C CD2 . TRP C  1 38 ? -12.06589 1.37472   -48.09112 1.000 7.13003  ? 36  TRP E CD2 1 
ATOM   1691 N NE1 . TRP C  1 38 ? -14.26152 1.81714   -48.28126 1.000 6.92128  ? 36  TRP E NE1 1 
ATOM   1692 C CE2 . TRP C  1 38 ? -13.21980 1.78227   -47.38785 1.000 7.21387  ? 36  TRP E CE2 1 
ATOM   1693 C CE3 . TRP C  1 38 ? -10.85159 1.26126   -47.39948 1.000 7.93300  ? 36  TRP E CE3 1 
ATOM   1694 C CZ2 . TRP C  1 38 ? -13.19873 2.05904   -46.02532 1.000 7.16311  ? 36  TRP E CZ2 1 
ATOM   1695 C CZ3 . TRP C  1 38 ? -10.83195 1.53596   -46.05072 1.000 7.53667  ? 36  TRP E CZ3 1 
ATOM   1696 C CH2 . TRP C  1 38 ? -11.99850 1.92862   -45.37493 1.000 7.20120  ? 36  TRP E CH2 1 
ATOM   1697 N N   . TYR C  1 39 ? -8.54537  1.45600   -51.60273 1.000 7.04485  ? 37  TYR E N   1 
ATOM   1698 C CA  . TYR C  1 39 ? -7.37888  1.00054   -52.34344 1.000 8.14156  ? 37  TYR E CA  1 
ATOM   1699 C C   . TYR C  1 39 ? -6.39263  0.37061   -51.37051 1.000 7.14347  ? 37  TYR E C   1 
ATOM   1700 O O   . TYR C  1 39 ? -6.46966  0.57375   -50.15376 1.000 8.14705  ? 37  TYR E O   1 
ATOM   1701 C CB  . TYR C  1 39 ? -6.72341  2.13468   -53.14760 1.000 8.79735  ? 37  TYR E CB  1 
ATOM   1702 C CG  . TYR C  1 39 ? -6.22746  3.28959   -52.29948 1.000 7.53098  ? 37  TYR E CG  1 
ATOM   1703 C CD1 . TYR C  1 39 ? -7.09670  4.28298   -51.85310 1.000 8.22916  ? 37  TYR E CD1 1 
ATOM   1704 C CD2 . TYR C  1 39 ? -4.88749  3.38949   -51.94522 1.000 7.91085  ? 37  TYR E CD2 1 
ATOM   1705 C CE1 . TYR C  1 39 ? -6.64867  5.33425   -51.07292 1.000 7.67247  ? 37  TYR E CE1 1 
ATOM   1706 C CE2 . TYR C  1 39 ? -4.42952  4.43440   -51.16614 1.000 8.21458  ? 37  TYR E CE2 1 
ATOM   1707 C CZ  . TYR C  1 39 ? -5.30970  5.40655   -50.73536 1.000 8.36291  ? 37  TYR E CZ  1 
ATOM   1708 O OH  . TYR C  1 39 ? -4.83373  6.43941   -49.95735 1.000 8.84460  ? 37  TYR E OH  1 
ATOM   1709 N N   . THR C  1 40 ? -5.47313  -0.41315  -51.90950 1.000 7.53495  ? 38  THR E N   1 
ATOM   1710 C CA  . THR C  1 40 ? -4.51240  -1.11945  -51.07133 1.000 7.57466  ? 38  THR E CA  1 
ATOM   1711 C C   . THR C  1 40 ? -3.34136  -0.21561  -50.71053 1.000 7.19591  ? 38  THR E C   1 
ATOM   1712 O O   . THR C  1 40 ? -2.78376  0.46735   -51.57207 1.000 8.09662  ? 38  THR E O   1 
ATOM   1713 C CB  . THR C  1 40 ? -4.06003  -2.38923  -51.78368 1.000 8.55519  ? 38  THR E CB  1 
ATOM   1714 O OG1 . THR C  1 40 ? -5.20994  -3.22886  -51.93374 1.000 9.96398  ? 38  THR E OG1 1 
ATOM   1715 C CG2 . THR C  1 40 ? -2.98005  -3.13113  -50.99827 1.000 9.31683  ? 38  THR E CG2 1 
ATOM   1716 N N   . GLY C  1 41 ? -2.99456  -0.18684  -49.42094 1.000 7.11910  ? 39  GLY E N   1 
ATOM   1717 C CA  . GLY C  1 41 ? -1.90686  0.63350   -48.94218 1.000 8.23422  ? 39  GLY E CA  1 
ATOM   1718 C C   . GLY C  1 41 ? -0.56548  -0.08545  -48.94897 1.000 7.10814  ? 39  GLY E C   1 
ATOM   1719 O O   . GLY C  1 41 ? -0.44581  -1.27655  -49.24009 1.000 7.73886  ? 39  GLY E O   1 
ATOM   1720 N N   . ALA C  1 42 ? 0.46554   0.67137   -48.57167 1.000 8.19371  ? 40  ALA E N   1 
ATOM   1721 C CA  . ALA C  1 42 ? 1.83572   0.17480   -48.58365 1.000 8.26810  ? 40  ALA E CA  1 
ATOM   1722 C C   . ALA C  1 42 ? 2.16437   -0.72990  -47.40461 1.000 8.41567  ? 40  ALA E C   1 
ATOM   1723 O O   . ALA C  1 42 ? 3.18295   -1.43154  -47.45531 1.000 9.22564  ? 40  ALA E O   1 
ATOM   1724 C CB  . ALA C  1 42 ? 2.82014   1.34597   -48.61136 1.000 8.70570  ? 40  ALA E CB  1 
ATOM   1725 N N   . PHE C  1 43 ? 1.34988   -0.73785  -46.34945 1.000 8.31806  ? 41  PHE E N   1 
ATOM   1726 C CA  . PHE C  1 43 ? 1.69274   -1.50398  -45.15869 1.000 7.66089  ? 41  PHE E CA  1 
ATOM   1727 C C   . PHE C  1 43 ? 1.59814   -2.99778  -45.43048 1.000 8.56014  ? 41  PHE E C   1 
ATOM   1728 O O   . PHE C  1 43 ? 0.55094   -3.49552  -45.85576 1.000 10.17055 ? 41  PHE E O   1 
ATOM   1729 C CB  . PHE C  1 43 ? 0.76181   -1.15219  -44.00531 1.000 8.24433  ? 41  PHE E CB  1 
ATOM   1730 C CG  . PHE C  1 43 ? 1.14329   -1.82260  -42.71809 1.000 8.53218  ? 41  PHE E CG  1 
ATOM   1731 C CD1 . PHE C  1 43 ? 0.73242   -3.11652  -42.42956 1.000 9.38965  ? 41  PHE E CD1 1 
ATOM   1732 C CD2 . PHE C  1 43 ? 1.94253   -1.17233  -41.80641 1.000 10.41084 ? 41  PHE E CD2 1 
ATOM   1733 C CE1 . PHE C  1 43 ? 1.11465   -3.73774  -41.25664 1.000 10.09856 ? 41  PHE E CE1 1 
ATOM   1734 C CE2 . PHE C  1 43 ? 2.31093   -1.78656  -40.62531 1.000 10.86812 ? 41  PHE E CE2 1 
ATOM   1735 C CZ  . PHE C  1 43 ? 1.90548   -3.07137  -40.35907 1.000 10.37665 ? 41  PHE E CZ  1 
ATOM   1736 N N   . ASN C  1 44 ? 2.67176   -3.72205  -45.12230 1.000 8.56042  ? 42  ASN E N   1 
ATOM   1737 C CA  . ASN C  1 44 ? 2.67031   -5.17438  -45.26391 1.000 9.18821  ? 42  ASN E CA  1 
ATOM   1738 C C   . ASN C  1 44 ? 3.71401   -5.71731  -44.29669 1.000 9.56041  ? 42  ASN E C   1 
ATOM   1739 O O   . ASN C  1 44 ? 4.91330   -5.52338  -44.51657 1.000 11.92876 ? 42  ASN E O   1 
ATOM   1740 C CB  . ASN C  1 44 ? 2.99066   -5.55672  -46.70115 1.000 12.43550 ? 42  ASN E CB  1 
ATOM   1741 C CG  . ASN C  1 44 ? 2.60369   -6.97952  -47.01318 1.000 22.63563 ? 42  ASN E CG  1 
ATOM   1742 O OD1 . ASN C  1 44 ? 2.99328   -7.90721  -46.30177 1.000 21.52624 ? 42  ASN E OD1 1 
ATOM   1743 N ND2 . ASN C  1 44 ? 1.80939   -7.16303  -48.06510 1.000 30.55941 ? 42  ASN E ND2 1 
ATOM   1744 N N   . GLU C  1 45 ? 3.26755   -6.34798  -43.21095 1.000 9.15416  ? 43  GLU E N   1 
ATOM   1745 C CA  . GLU C  1 45 ? 4.18375   -6.84806  -42.19377 1.000 9.38206  ? 43  GLU E CA  1 
ATOM   1746 C C   . GLU C  1 45 ? 3.61664   -8.12384  -41.60088 1.000 9.27876  ? 43  GLU E C   1 
ATOM   1747 O O   . GLU C  1 45 ? 2.39599   -8.31204  -41.59429 1.000 9.61122  ? 43  GLU E O   1 
ATOM   1748 C CB  . GLU C  1 45 ? 4.39147   -5.83814  -41.05310 1.000 11.00122 ? 43  GLU E CB  1 
ATOM   1749 C CG  . GLU C  1 45 ? 4.91199   -4.48238  -41.47881 1.000 12.16647 ? 43  GLU E CG  1 
ATOM   1750 C CD  . GLU C  1 45 ? 6.33257   -4.52558  -41.99331 1.000 13.91675 ? 43  GLU E CD  1 
ATOM   1751 O OE1 . GLU C  1 45 ? 6.99734   -5.58021  -41.89477 1.000 14.95461 ? 43  GLU E OE1 1 
ATOM   1752 O OE2 . GLU C  1 45 ? 6.79267   -3.48421  -42.49960 1.000 14.59232 ? 43  GLU E OE2 1 
ATOM   1753 N N   . PRO C  1 46 ? 4.46469   -8.99903  -41.06286 1.000 9.91500  ? 44  PRO E N   1 
ATOM   1754 C CA  . PRO C  1 46 ? 3.94774   -10.20342 -40.40625 1.000 9.66540  ? 44  PRO E CA  1 
ATOM   1755 C C   . PRO C  1 46 ? 3.17141   -9.85382  -39.14874 1.000 9.66693  ? 44  PRO E C   1 
ATOM   1756 O O   . PRO C  1 46 ? 3.48541   -8.89620  -38.43593 1.000 10.64399 ? 44  PRO E O   1 
ATOM   1757 C CB  . PRO C  1 46 ? 5.21514   -10.98702 -40.04515 1.000 13.92976 ? 44  PRO E CB  1 
ATOM   1758 C CG  . PRO C  1 46 ? 6.29997   -10.41446 -40.90144 1.000 13.37605 ? 44  PRO E CG  1 
ATOM   1759 C CD  . PRO C  1 46 ? 5.93789   -8.97436  -41.10341 1.000 11.26004 ? 44  PRO E CD  1 
ATOM   1760 N N   . GLY C  1 47 ? 2.15895   -10.66348 -38.86491 1.000 10.07945 ? 45  GLY E N   1 
ATOM   1761 C CA  . GLY C  1 47 ? 1.43138   -10.53274 -37.62103 1.000 11.06355 ? 45  GLY E CA  1 
ATOM   1762 C C   . GLY C  1 47 ? 0.22861   -11.44546 -37.53892 1.000 10.59458 ? 45  GLY E C   1 
ATOM   1763 O O   . GLY C  1 47 ? -0.47601  -11.65074 -38.53477 1.000 12.70664 ? 45  GLY E O   1 
ATOM   1764 N N   . ASP C  1 48 ? 0.00161   -12.00687 -36.34792 1.000 10.66924 ? 46  ASP E N   1 
ATOM   1765 C CA  . ASP C  1 48 ? -1.20949  -12.74843 -36.01426 1.000 14.63438 ? 46  ASP E CA  1 
ATOM   1766 C C   . ASP C  1 48 ? -2.30754  -11.82976 -35.51176 1.000 10.12550 ? 46  ASP E C   1 
ATOM   1767 O O   . ASP C  1 48 ? -3.49286  -12.15129 -35.64542 1.000 13.92500 ? 46  ASP E O   1 
ATOM   1768 C CB  . ASP C  1 48 ? -0.94093  -13.71450 -34.85177 1.000 19.13702 ? 46  ASP E CB  1 
ATOM   1769 C CG  . ASP C  1 48 ? 0.19903   -14.67086 -35.11436 1.000 26.90707 ? 46  ASP E CG  1 
ATOM   1770 O OD1 . ASP C  1 48 ? 0.27777   -15.21419 -36.23032 1.000 33.66253 ? 46  ASP E OD1 1 
ATOM   1771 O OD2 . ASP C  1 48 ? 1.00916   -14.88714 -34.18635 1.000 35.43280 ? 46  ASP E OD2 1 
ATOM   1772 N N   . ASN C  1 49 ? -1.92139  -10.70656 -34.91340 1.000 9.89034  ? 47  ASN E N   1 
ATOM   1773 C CA  . ASN C  1 49 ? -2.80915  -9.80687  -34.19685 1.000 10.43443 ? 47  ASN E CA  1 
ATOM   1774 C C   . ASN C  1 49 ? -2.37181  -8.38442  -34.49580 1.000 8.54397  ? 47  ASN E C   1 
ATOM   1775 O O   . ASN C  1 49 ? -1.17773  -8.12068  -34.66105 1.000 8.62317  ? 47  ASN E O   1 
ATOM   1776 C CB  . ASN C  1 49 ? -2.65230  -10.04935 -32.67920 1.000 14.40509 ? 47  ASN E CB  1 
ATOM   1777 C CG  . ASN C  1 49 ? -3.42392  -9.05326  -31.83548 1.000 14.94831 ? 47  ASN E CG  1 
ATOM   1778 O OD1 . ASN C  1 49 ? -2.86739  -8.07843  -31.31773 1.000 16.16445 ? 47  ASN E OD1 1 
ATOM   1779 N ND2 . ASN C  1 49 ? -4.71771  -9.29660  -31.68877 1.000 17.89100 ? 47  ASN E ND2 1 
ATOM   1780 N N   . VAL C  1 50 ? -3.33060  -7.46383  -34.54160 1.000 7.78216  ? 48  VAL E N   1 
ATOM   1781 C CA  . VAL C  1 50 ? -3.01606  -6.09023  -34.90190 1.000 7.42003  ? 48  VAL E CA  1 
ATOM   1782 C C   . VAL C  1 50 ? -3.86683  -5.11630  -34.10098 1.000 6.79706  ? 48  VAL E C   1 
ATOM   1783 O O   . VAL C  1 50 ? -5.06373  -5.34033  -33.88292 1.000 7.47934  ? 48  VAL E O   1 
ATOM   1784 C CB  . VAL C  1 50 ? -3.17060  -5.86207  -36.42434 1.000 8.07047  ? 48  VAL E CB  1 
ATOM   1785 C CG1 . VAL C  1 50 ? -4.60793  -6.10754  -36.89389 1.000 9.51196  ? 48  VAL E CG1 1 
ATOM   1786 C CG2 . VAL C  1 50 ? -2.68188  -4.47484  -36.81560 1.000 9.09010  ? 48  VAL E CG2 1 
ATOM   1787 N N   . SER C  1 51 ? -3.24090  -4.02376  -33.66991 1.000 6.67094  ? 49  SER E N   1 
ATOM   1788 C CA  . SER C  1 51 ? -3.95384  -2.85241  -33.18503 1.000 6.67681  ? 49  SER E CA  1 
ATOM   1789 C C   . SER C  1 51 ? -3.32606  -1.61868  -33.81992 1.000 6.19648  ? 49  SER E C   1 
ATOM   1790 O O   . SER C  1 51 ? -2.22509  -1.67199  -34.38010 1.000 6.66664  ? 49  SER E O   1 
ATOM   1791 C CB  . SER C  1 51 ? -3.95791  -2.75529  -31.65107 1.000 7.49267  ? 49  SER E CB  1 
ATOM   1792 O OG  . SER C  1 51 ? -2.67834  -2.46692  -31.12088 1.000 7.80199  ? 49  SER E OG  1 
ATOM   1793 N N   . VAL C  1 52 ? -4.02039  -0.48879  -33.72948 1.000 6.28198  ? 50  VAL E N   1 
ATOM   1794 C CA  . VAL C  1 52 ? -3.55821  0.73204   -34.38003 1.000 6.27666  ? 50  VAL E CA  1 
ATOM   1795 C C   . VAL C  1 52 ? -4.03940  1.93527   -33.58724 1.000 6.21965  ? 50  VAL E C   1 
ATOM   1796 O O   . VAL C  1 52 ? -5.09368  1.90124   -32.94823 1.000 7.66879  ? 50  VAL E O   1 
ATOM   1797 C CB  . VAL C  1 52 ? -4.03407  0.81355   -35.85360 1.000 6.95087  ? 50  VAL E CB  1 
ATOM   1798 C CG1 . VAL C  1 52 ? -5.55820  0.93553   -35.94599 1.000 8.55036  ? 50  VAL E CG1 1 
ATOM   1799 C CG2 . VAL C  1 52 ? -3.35185  1.96140   -36.58750 1.000 7.29496  ? 50  VAL E CG2 1 
ATOM   1800 N N   . THR C  1 53 ? -3.25665  3.01020   -33.63764 1.000 6.79793  ? 51  THR E N   1 
ATOM   1801 C CA  . THR C  1 53 ? -3.70656  4.32548   -33.22211 1.000 6.37305  ? 51  THR E CA  1 
ATOM   1802 C C   . THR C  1 53 ? -3.06930  5.34284   -34.15977 1.000 7.16035  ? 51  THR E C   1 
ATOM   1803 O O   . THR C  1 53 ? -2.09416  5.04508   -34.84988 1.000 8.10302  ? 51  THR E O   1 
ATOM   1804 C CB  . THR C  1 53 ? -3.37675  4.60022   -31.74028 1.000 8.18508  ? 51  THR E CB  1 
ATOM   1805 O OG1 . THR C  1 53 ? -4.04153  5.78932   -31.30380 1.000 7.84324  ? 51  THR E OG1 1 
ATOM   1806 C CG2 . THR C  1 53 ? -1.88013  4.74634   -31.52090 1.000 9.09610  ? 51  THR E CG2 1 
ATOM   1807 N N   . SER C  1 54 ? -3.63124  6.54545   -34.20585 1.000 6.74086  ? 52  SER E N   1 
ATOM   1808 C CA  . SER C  1 54 ? -3.06563  7.59712   -35.04010 1.000 7.64780  ? 52  SER E CA  1 
ATOM   1809 C C   . SER C  1 54 ? -3.40031  8.94150   -34.41796 1.000 6.74638  ? 52  SER E C   1 
ATOM   1810 O O   . SER C  1 54 ? -4.34728  9.06239   -33.63815 1.000 7.80468  ? 52  SER E O   1 
ATOM   1811 C CB  . SER C  1 54 ? -3.58567  7.53272   -36.48223 1.000 7.60767  ? 52  SER E CB  1 
ATOM   1812 O OG  . SER C  1 54 ? -4.95881  7.86234   -36.56875 1.000 8.35423  ? 52  SER E OG  1 
ATOM   1813 N N   . TRP C  1 55 ? -2.60565  9.95363   -34.76778 1.000 7.53082  ? 53  TRP E N   1 
ATOM   1814 C CA  . TRP C  1 55 ? -2.84384  11.31268  -34.30533 1.000 8.24804  ? 53  TRP E CA  1 
ATOM   1815 C C   . TRP C  1 55 ? -2.37760  12.28348  -35.37587 1.000 8.53119  ? 53  TRP E C   1 
ATOM   1816 O O   . TRP C  1 55 ? -1.46284  11.99353  -36.15286 1.000 9.13954  ? 53  TRP E O   1 
ATOM   1817 C CB  . TRP C  1 55 ? -2.12128  11.61211  -32.98113 1.000 9.63344  ? 53  TRP E CB  1 
ATOM   1818 C CG  . TRP C  1 55 ? -0.63916  11.54612  -33.10044 1.000 9.68556  ? 53  TRP E CG  1 
ATOM   1819 C CD1 . TRP C  1 55 ? 0.21464   12.58889  -33.34758 1.000 9.75135  ? 53  TRP E CD1 1 
ATOM   1820 C CD2 . TRP C  1 55 ? 0.17397   10.37303  -33.00894 1.000 9.45082  ? 53  TRP E CD2 1 
ATOM   1821 N NE1 . TRP C  1 55 ? 1.50446   12.13244  -33.40759 1.000 10.71912 ? 53  TRP E NE1 1 
ATOM   1822 C CE2 . TRP C  1 55 ? 1.50946   10.77732  -33.19907 1.000 9.15699  ? 53  TRP E CE2 1 
ATOM   1823 C CE3 . TRP C  1 55 ? -0.09595  9.02127   -32.76281 1.000 10.15902 ? 53  TRP E CE3 1 
ATOM   1824 C CZ2 . TRP C  1 55 ? 2.56856   9.88011   -33.17186 1.000 9.72372  ? 53  TRP E CZ2 1 
ATOM   1825 C CZ3 . TRP C  1 55 ? 0.95498   8.13229   -32.73460 1.000 9.19460  ? 53  TRP E CZ3 1 
ATOM   1826 C CH2 . TRP C  1 55 ? 2.27656   8.56353   -32.93939 1.000 9.42892  ? 53  TRP E CH2 1 
ATOM   1827 N N   . LEU C  1 56 ? -3.02682  13.43730  -35.40924 1.000 9.31506  ? 54  LEU E N   1 
ATOM   1828 C CA  . LEU C  1 56 ? -2.64105  14.52380  -36.29054 1.000 10.07375 ? 54  LEU E CA  1 
ATOM   1829 C C   . LEU C  1 56 ? -1.70916  15.48215  -35.56786 1.000 10.73841 ? 54  LEU E C   1 
ATOM   1830 O O   . LEU C  1 56 ? -1.89952  15.79291  -34.38627 1.000 12.66357 ? 54  LEU E O   1 
ATOM   1831 C CB  . LEU C  1 56 ? -3.87481  15.30346  -36.73851 1.000 10.42488 ? 54  LEU E CB  1 
ATOM   1832 C CG  . LEU C  1 56 ? -4.73299  14.61720  -37.79119 1.000 11.00216 ? 54  LEU E CG  1 
ATOM   1833 C CD1 . LEU C  1 56 ? -6.06027  15.35487  -37.93096 1.000 14.70423 ? 54  LEU E CD1 1 
ATOM   1834 C CD2 . LEU C  1 56 ? -4.00686  14.56764  -39.12613 1.000 13.69854 ? 54  LEU E CD2 1 
ATOM   1835 N N   . VAL C  1 57 ? -0.70451  15.95238  -36.29013 1.000 10.76780 ? 55  VAL E N   1 
ATOM   1836 C CA  . VAL C  1 57 ? 0.10967   17.08534  -35.87620 1.000 10.69683 ? 55  VAL E CA  1 
ATOM   1837 C C   . VAL C  1 57 ? -0.13801  18.13674  -36.94974 1.000 12.48166 ? 55  VAL E C   1 
ATOM   1838 O O   . VAL C  1 57 ? 0.41584   18.05382  -38.05149 1.000 12.81236 ? 55  VAL E O   1 
ATOM   1839 C CB  . VAL C  1 57 ? 1.59090   16.71900  -35.76399 1.000 12.27730 ? 55  VAL E CB  1 
ATOM   1840 C CG1 . VAL C  1 57 ? 2.40154   17.93745  -35.41348 1.000 15.65534 ? 55  VAL E CG1 1 
ATOM   1841 C CG2 . VAL C  1 57 ? 1.79292   15.62709  -34.71987 1.000 13.44147 ? 55  VAL E CG2 1 
ATOM   1842 N N   . GLY C  1 58 ? -1.01279  19.09323  -36.66064 1.000 13.60419 ? 56  GLY E N   1 
ATOM   1843 C CA  . GLY C  1 58 ? -1.50930  19.94594  -37.72672 1.000 15.51540 ? 56  GLY E CA  1 
ATOM   1844 C C   . GLY C  1 58 ? -2.26985  19.09865  -38.72976 1.000 14.83568 ? 56  GLY E C   1 
ATOM   1845 O O   . GLY C  1 58 ? -3.17983  18.34014  -38.37243 1.000 16.54062 ? 56  GLY E O   1 
ATOM   1846 N N   . SER C  1 59 ? -1.89150  19.19913  -39.99930 1.000 15.09417 ? 57  SER E N   1 
ATOM   1847 C CA  . SER C  1 59 ? -2.52196  18.37688  -41.02345 1.000 14.70509 ? 57  SER E CA  1 
ATOM   1848 C C   . SER C  1 59 ? -1.81444  17.04423  -41.24553 1.000 15.05900 ? 57  SER E C   1 
ATOM   1849 O O   . SER C  1 59 ? -2.32682  16.21510  -42.00453 1.000 15.29758 ? 57  SER E O   1 
ATOM   1850 C CB  . SER C  1 59 ? -2.63077  19.14219  -42.34820 1.000 19.44432 ? 57  SER E CB  1 
ATOM   1851 O OG  . SER C  1 59 ? -1.35286  19.36974  -42.91161 1.000 20.99210 ? 57  SER E OG  1 
ATOM   1852 N N   . ALA C  1 60 ? -0.67051  16.81066  -40.60353 1.000 12.91500 ? 58  ALA E N   1 
ATOM   1853 C CA  . ALA C  1 60 ? 0.14399   15.62599  -40.86265 1.000 13.93778 ? 58  ALA E CA  1 
ATOM   1854 C C   . ALA C  1 60 ? -0.30160  14.46094  -39.98744 1.000 10.54382 ? 58  ALA E C   1 
ATOM   1855 O O   . ALA C  1 60 ? -0.32453  14.57215  -38.75607 1.000 11.21175 ? 58  ALA E O   1 
ATOM   1856 C CB  . ALA C  1 60 ? 1.61576   15.92715  -40.58572 1.000 14.43000 ? 58  ALA E CB  1 
ATOM   1857 N N   . ILE C  1 61 ? -0.62534  13.33691  -40.62189 1.000 9.37996  ? 59  ILE E N   1 
ATOM   1858 C CA  . ILE C  1 61 ? -1.04772  12.14817  -39.89291 1.000 8.77203  ? 59  ILE E CA  1 
ATOM   1859 C C   . ILE C  1 61 ? 0.16691   11.33295  -39.47864 1.000 8.26837  ? 59  ILE E C   1 
ATOM   1860 O O   . ILE C  1 61 ? 1.14033   11.19627  -40.22678 1.000 9.76023  ? 59  ILE E O   1 
ATOM   1861 C CB  . ILE C  1 61 ? -2.05546  11.31148  -40.70761 1.000 9.52316  ? 59  ILE E CB  1 
ATOM   1862 C CG1 . ILE C  1 61 ? -2.68688  10.21786  -39.83800 1.000 8.91256  ? 59  ILE E CG1 1 
ATOM   1863 C CG2 . ILE C  1 61 ? -1.40302  10.69559  -41.92656 1.000 10.26334 ? 59  ILE E CG2 1 
ATOM   1864 C CD1 . ILE C  1 61 ? -3.53689  10.74780  -38.71135 1.000 9.34365  ? 59  ILE E CD1 1 
ATOM   1865 N N   . HIS C  1 62 ? 0.10017   10.77826  -38.27182 1.000 8.63339  ? 60  HIS E N   1 
ATOM   1866 C CA  . HIS C  1 62 ? 1.08662   9.83521   -37.77211 1.000 7.72486  ? 60  HIS E CA  1 
ATOM   1867 C C   . HIS C  1 62 ? 0.33754   8.59301   -37.32878 1.000 7.22029  ? 60  HIS E C   1 
ATOM   1868 O O   . HIS C  1 62 ? -0.62441  8.69639   -36.56527 1.000 8.19557  ? 60  HIS E O   1 
ATOM   1869 C CB  . HIS C  1 62 ? 1.84158   10.44154  -36.59675 1.000 8.60709  ? 60  HIS E CB  1 
ATOM   1870 C CG  . HIS C  1 62 ? 2.59779   11.67229  -36.97186 1.000 10.46730 ? 60  HIS E CG  1 
ATOM   1871 N ND1 . HIS C  1 62 ? 3.92951   11.64847  -37.31995 1.000 11.81283 ? 60  HIS E ND1 1 
ATOM   1872 C CD2 . HIS C  1 62 ? 2.19043   12.95407  -37.12449 1.000 11.20499 ? 60  HIS E CD2 1 
ATOM   1873 C CE1 . HIS C  1 62 ? 4.32057   12.87084  -37.64184 1.000 13.49927 ? 60  HIS E CE1 1 
ATOM   1874 N NE2 . HIS C  1 62 ? 3.28352   13.68144  -37.53171 1.000 13.80697 ? 60  HIS E NE2 1 
ATOM   1875 N N   . ILE C  1 63 ? 0.75954   7.42830   -37.82097 1.000 7.57409  ? 61  ILE E N   1 
ATOM   1876 C CA  . ILE C  1 63 ? 0.07431   6.16804   -37.55090 1.000 7.18028  ? 61  ILE E CA  1 
ATOM   1877 C C   . ILE C  1 63 ? 1.04382   5.22524   -36.85636 1.000 6.84546  ? 61  ILE E C   1 
ATOM   1878 O O   . ILE C  1 63 ? 2.21780   5.15445   -37.23498 1.000 7.77874  ? 61  ILE E O   1 
ATOM   1879 C CB  . ILE C  1 63 ? -0.44887  5.51191   -38.84673 1.000 7.12878  ? 61  ILE E CB  1 
ATOM   1880 C CG1 . ILE C  1 63 ? -1.22499  6.51277   -39.71237 1.000 8.43511  ? 61  ILE E CG1 1 
ATOM   1881 C CG2 . ILE C  1 63 ? -1.30292  4.29910   -38.51278 1.000 7.87399  ? 61  ILE E CG2 1 
ATOM   1882 C CD1 . ILE C  1 63 ? -1.54561  5.98668   -41.10338 1.000 9.16476  ? 61  ILE E CD1 1 
ATOM   1883 N N   . ARG C  1 64 ? 0.55627   4.49256   -35.85681 1.000 7.02984  ? 62  ARG E N   1 
ATOM   1884 C CA  . ARG C  1 64 ? 1.34025   3.44551   -35.21430 1.000 7.30306  ? 62  ARG E CA  1 
ATOM   1885 C C   . ARG C  1 64 ? 0.53681   2.16004   -35.25824 1.000 6.67182  ? 62  ARG E C   1 
ATOM   1886 O O   . ARG C  1 64 ? -0.58239  2.11155   -34.74204 1.000 7.25228  ? 62  ARG E O   1 
ATOM   1887 C CB  . ARG C  1 64 ? 1.66620   3.81784   -33.76654 1.000 7.86583  ? 62  ARG E CB  1 
ATOM   1888 C CG  . ARG C  1 64 ? 2.51363   5.06833   -33.62195 1.000 8.18414  ? 62  ARG E CG  1 
ATOM   1889 C CD  . ARG C  1 64 ? 3.89413   4.87631   -34.23956 1.000 8.44850  ? 62  ARG E CD  1 
ATOM   1890 N NE  . ARG C  1 64 ? 4.74718   6.05601   -34.10842 1.000 9.29059  ? 62  ARG E NE  1 
ATOM   1891 C CZ  . ARG C  1 64 ? 4.82551   7.04474   -34.98733 1.000 9.74188  ? 62  ARG E CZ  1 
ATOM   1892 N NH1 . ARG C  1 64 ? 4.12051   7.03933   -36.10658 1.000 9.56473  ? 62  ARG E NH1 1 
ATOM   1893 N NH2 . ARG C  1 64 ? 5.63440   8.07243   -34.73529 1.000 11.97871 ? 62  ARG E NH2 1 
ATOM   1894 N N   . VAL C  1 65 ? 1.10193   1.12902   -35.87276 1.000 6.36213  ? 63  VAL E N   1 
ATOM   1895 C CA  . VAL C  1 65 ? 0.48236   -0.18479  -35.96471 1.000 5.96918  ? 63  VAL E CA  1 
ATOM   1896 C C   . VAL C  1 65 ? 1.28111   -1.13298  -35.08577 1.000 6.62713  ? 63  VAL E C   1 
ATOM   1897 O O   . VAL C  1 65 ? 2.50918   -1.21022  -35.20805 1.000 7.96303  ? 63  VAL E O   1 
ATOM   1898 C CB  . VAL C  1 65 ? 0.45560   -0.69144  -37.41874 1.000 7.51165  ? 63  VAL E CB  1 
ATOM   1899 C CG1 . VAL C  1 65 ? -0.05525  -2.11957  -37.47932 1.000 7.83874  ? 63  VAL E CG1 1 
ATOM   1900 C CG2 . VAL C  1 65 ? -0.39581  0.21374   -38.28696 1.000 8.13796  ? 63  VAL E CG2 1 
ATOM   1901 N N   . TYR C  1 66 ? 0.59403   -1.84462  -34.19781 1.000 6.36364  ? 64  TYR E N   1 
ATOM   1902 C CA  . TYR C  1 66 ? 1.22201   -2.79375  -33.27939 1.000 7.18816  ? 64  TYR E CA  1 
ATOM   1903 C C   . TYR C  1 66 ? 0.91072   -4.19050  -33.79133 1.000 6.52040  ? 64  TYR E C   1 
ATOM   1904 O O   . TYR C  1 66 ? -0.23451  -4.64224  -33.70950 1.000 7.19590  ? 64  TYR E O   1 
ATOM   1905 C CB  . TYR C  1 66 ? 0.76357   -2.55344  -31.82943 1.000 6.56758  ? 64  TYR E CB  1 
ATOM   1906 C CG  . TYR C  1 66 ? 1.19137   -1.16802  -31.41478 1.000 7.11195  ? 64  TYR E CG  1 
ATOM   1907 C CD1 . TYR C  1 66 ? 2.46623   -0.92980  -30.93586 1.000 7.62246  ? 64  TYR E CD1 1 
ATOM   1908 C CD2 . TYR C  1 66 ? 0.35742   -0.08176  -31.60609 1.000 6.91255  ? 64  TYR E CD2 1 
ATOM   1909 C CE1 . TYR C  1 66 ? 2.88345   0.35942   -30.63726 1.000 7.99622  ? 64  TYR E CE1 1 
ATOM   1910 C CE2 . TYR C  1 66 ? 0.76904   1.20874   -31.31951 1.000 7.65338  ? 64  TYR E CE2 1 
ATOM   1911 C CZ  . TYR C  1 66 ? 2.03657   1.42483   -30.83712 1.000 6.51439  ? 64  TYR E CZ  1 
ATOM   1912 O OH  . TYR C  1 66 ? 2.43785   2.71995   -30.57532 1.000 8.23714  ? 64  TYR E OH  1 
ATOM   1913 N N   . ALA C  1 67 ? 1.91644   -4.84235  -34.35837 1.000 7.04734  ? 65  ALA E N   1 
ATOM   1914 C CA  . ALA C  1 67 ? 1.77585   -6.14995  -34.97939 1.000 7.17953  ? 65  ALA E CA  1 
ATOM   1915 C C   . ALA C  1 67 ? 2.39847   -7.18182  -34.05631 1.000 8.17004  ? 65  ALA E C   1 
ATOM   1916 O O   . ALA C  1 67 ? 3.56288   -7.04088  -33.66904 1.000 9.35963  ? 65  ALA E O   1 
ATOM   1917 C CB  . ALA C  1 67 ? 2.52422   -6.18192  -36.31523 1.000 8.56281  ? 65  ALA E CB  1 
ATOM   1918 N N   . SER C  1 68 ? 1.64677   -8.22229  -33.71425 1.000 8.22205  ? 66  SER E N   1 
ATOM   1919 C CA  . SER C  1 68 ? 2.14421   -9.22144  -32.78203 1.000 8.61332  ? 66  SER E CA  1 
ATOM   1920 C C   . SER C  1 68 ? 2.14475   -10.60317 -33.41153 1.000 9.18625  ? 66  SER E C   1 
ATOM   1921 O O   . SER C  1 68 ? 1.19367   -10.99080 -34.09527 1.000 9.66708  ? 66  SER E O   1 
ATOM   1922 C CB  . SER C  1 68 ? 1.32525   -9.24948  -31.49364 1.000 10.44773 ? 66  SER E CB  1 
ATOM   1923 O OG  . SER C  1 68 ? 1.37778   -7.99079  -30.83653 1.000 10.73290 ? 66  SER E OG  1 
ATOM   1924 N N   . THR C  1 69 ? 3.22140   -11.34035 -33.15980 1.000 9.34465  ? 67  THR E N   1 
ATOM   1925 C CA  . THR C  1 69 ? 3.34103   -12.74421 -33.52419 1.000 11.73114 ? 67  THR E CA  1 
ATOM   1926 C C   . THR C  1 69 ? 3.92002   -13.45891 -32.31359 1.000 11.22214 ? 67  THR E C   1 
ATOM   1927 O O   . THR C  1 69 ? 4.95814   -13.04670 -31.79084 1.000 12.89275 ? 67  THR E O   1 
ATOM   1928 C CB  . THR C  1 69 ? 4.27370   -12.92595 -34.73198 1.000 14.24356 ? 67  THR E CB  1 
ATOM   1929 O OG1 . THR C  1 69 ? 3.78475   -12.16886 -35.84612 1.000 15.90477 ? 67  THR E OG1 1 
ATOM   1930 C CG2 . THR C  1 69 ? 4.35715   -14.39240 -35.12916 1.000 17.25250 ? 67  THR E CG2 1 
ATOM   1931 N N   . GLY C  1 70 ? 3.25054   -14.51172 -31.86200 1.000 11.25942 ? 68  GLY E N   1 
ATOM   1932 C CA  . GLY C  1 70 ? 3.69761   -15.18430 -30.65891 1.000 12.02628 ? 68  GLY E CA  1 
ATOM   1933 C C   . GLY C  1 70 ? 3.58375   -14.24710 -29.47589 1.000 10.91893 ? 68  GLY E C   1 
ATOM   1934 O O   . GLY C  1 70 ? 2.48682   -13.76472 -29.17559 1.000 12.59584 ? 68  GLY E O   1 
ATOM   1935 N N   . THR C  1 71 ? 4.70172   -13.95285 -28.81424 1.000 11.92487 ? 69  THR E N   1 
ATOM   1936 C CA  . THR C  1 71 ? 4.71598   -12.98740 -27.72289 1.000 12.81140 ? 69  THR E CA  1 
ATOM   1937 C C   . THR C  1 71 ? 5.48617   -11.72142 -28.06495 1.000 11.53800 ? 69  THR E C   1 
ATOM   1938 O O   . THR C  1 71 ? 5.79613   -10.93910 -27.16262 1.000 13.87779 ? 69  THR E O   1 
ATOM   1939 C CB  . THR C  1 71 ? 5.26029   -13.60767 -26.43271 1.000 15.63680 ? 69  THR E CB  1 
ATOM   1940 O OG1 . THR C  1 71 ? 6.56790   -14.14222 -26.67184 1.000 17.75226 ? 69  THR E OG1 1 
ATOM   1941 C CG2 . THR C  1 71 ? 4.32997   -14.70539 -25.92720 1.000 17.17603 ? 69  THR E CG2 1 
ATOM   1942 N N   . THR C  1 72 ? 5.77758   -11.48389 -29.33809 1.000 10.73545 ? 70  THR E N   1 
ATOM   1943 C CA  . THR C  1 72 ? 6.58591   -10.34698 -29.75301 1.000 11.51236 ? 70  THR E CA  1 
ATOM   1944 C C   . THR C  1 72 ? 5.72119   -9.34597  -30.50723 1.000 10.33879 ? 70  THR E C   1 
ATOM   1945 O O   . THR C  1 72 ? 5.12938   -9.68476  -31.54039 1.000 11.72467 ? 70  THR E O   1 
ATOM   1946 C CB  . THR C  1 72 ? 7.72532   -10.82515 -30.64759 1.000 12.85557 ? 70  THR E CB  1 
ATOM   1947 O OG1 . THR C  1 72 ? 8.54194   -11.75387 -29.92111 1.000 17.08327 ? 70  THR E OG1 1 
ATOM   1948 C CG2 . THR C  1 72 ? 8.57988   -9.65002  -31.09548 1.000 14.58737 ? 70  THR E CG2 1 
ATOM   1949 N N   . THR C  1 73 ? 5.67659   -8.11562  -30.00997 1.000 9.76232  ? 71  THR E N   1 
ATOM   1950 C CA  . THR C  1 73 ? 4.96904   -7.02222  -30.65980 1.000 9.13517  ? 71  THR E CA  1 
ATOM   1951 C C   . THR C  1 73 ? 5.98150   -6.08930  -31.29862 1.000 10.54198 ? 71  THR E C   1 
ATOM   1952 O O   . THR C  1 73 ? 6.92011   -5.63209  -30.63439 1.000 12.25200 ? 71  THR E O   1 
ATOM   1953 C CB  . THR C  1 73 ? 4.14172   -6.23640  -29.64596 1.000 9.40144  ? 71  THR E CB  1 
ATOM   1954 O OG1 . THR C  1 73 ? 3.20647   -7.11213  -29.01072 1.000 10.57996 ? 71  THR E OG1 1 
ATOM   1955 C CG2 . THR C  1 73 ? 3.39982   -5.08310  -30.32918 1.000 10.27343 ? 71  THR E CG2 1 
ATOM   1956 N N   . THR C  1 74 ? 5.78128   -5.79881  -32.57609 1.000 8.84260  ? 72  THR E N   1 
ATOM   1957 C CA  . THR C  1 74 ? 6.58049   -4.82022  -33.28876 1.000 8.85433  ? 72  THR E CA  1 
ATOM   1958 C C   . THR C  1 74 ? 5.70053   -3.62657  -33.61355 1.000 7.59708  ? 72  THR E C   1 
ATOM   1959 O O   . THR C  1 74 ? 4.59299   -3.79141  -34.13520 1.000 8.63602  ? 72  THR E O   1 
ATOM   1960 C CB  . THR C  1 74 ? 7.12447   -5.41909  -34.58276 1.000 9.19259  ? 72  THR E CB  1 
ATOM   1961 O OG1 . THR C  1 74 ? 7.85656   -6.61495  -34.28113 1.000 11.03351 ? 72  THR E OG1 1 
ATOM   1962 C CG2 . THR C  1 74 ? 8.03812   -4.41985  -35.27757 1.000 11.36579 ? 72  THR E CG2 1 
ATOM   1963 N N   . GLU C  1 75 ? 6.19381   -2.43734  -33.31047 1.000 7.96441  ? 73  GLU E N   1 
ATOM   1964 C CA  . GLU C  1 75 ? 5.52622   -1.20035  -33.67032 1.000 7.82019  ? 73  GLU E CA  1 
ATOM   1965 C C   . GLU C  1 75 ? 6.03135   -0.73933  -35.02730 1.000 7.31883  ? 73  GLU E C   1 
ATOM   1966 O O   . GLU C  1 75 ? 7.24604   -0.68156  -35.25643 1.000 8.48455  ? 73  GLU E O   1 
ATOM   1967 C CB  . GLU C  1 75 ? 5.85843   -0.13028  -32.63762 1.000 9.03067  ? 73  GLU E CB  1 
ATOM   1968 C CG  . GLU C  1 75 ? 5.29092   1.24517   -32.92139 1.000 9.00227  ? 73  GLU E CG  1 
ATOM   1969 C CD  . GLU C  1 75 ? 5.82382   2.28966   -31.95354 1.000 8.52250  ? 73  GLU E CD  1 
ATOM   1970 O OE1 . GLU C  1 75 ? 7.05898   2.33648   -31.77637 1.000 9.68653  ? 73  GLU E OE1 1 
ATOM   1971 O OE2 . GLU C  1 75 ? 5.02699   3.06121   -31.38182 1.000 9.42075  ? 73  GLU E OE2 1 
ATOM   1972 N N   . TRP C  1 76 ? 5.10119   -0.39738  -35.90870 1.000 7.32795  ? 74  TRP E N   1 
ATOM   1973 C CA  . TRP C  1 76 ? 5.40140   0.14772   -37.22254 1.000 7.53450  ? 74  TRP E CA  1 
ATOM   1974 C C   . TRP C  1 76 ? 4.86547   1.56731   -37.30316 1.000 8.05678  ? 74  TRP E C   1 
ATOM   1975 O O   . TRP C  1 76 ? 3.73593   1.84038   -36.88398 1.000 7.76854  ? 74  TRP E O   1 
ATOM   1976 C CB  . TRP C  1 76 ? 4.79035   -0.72682  -38.31308 1.000 7.55237  ? 74  TRP E CB  1 
ATOM   1977 C CG  . TRP C  1 76 ? 5.42276   -2.07108  -38.34596 1.000 7.32844  ? 74  TRP E CG  1 
ATOM   1978 C CD1 . TRP C  1 76 ? 4.91546   -3.23676  -37.85306 1.000 8.41498  ? 74  TRP E CD1 1 
ATOM   1979 C CD2 . TRP C  1 76 ? 6.71059   -2.38419  -38.87236 1.000 8.99561  ? 74  TRP E CD2 1 
ATOM   1980 N NE1 . TRP C  1 76 ? 5.80362   -4.26845  -38.06183 1.000 9.86091  ? 74  TRP E NE1 1 
ATOM   1981 C CE2 . TRP C  1 76 ? 6.91811   -3.76593  -38.68101 1.000 10.20203 ? 74  TRP E CE2 1 
ATOM   1982 C CE3 . TRP C  1 76 ? 7.70725   -1.62985  -39.50001 1.000 10.65822 ? 74  TRP E CE3 1 
ATOM   1983 C CZ2 . TRP C  1 76 ? 8.08572   -4.41031  -39.09347 1.000 12.97557 ? 74  TRP E CZ2 1 
ATOM   1984 C CZ3 . TRP C  1 76 ? 8.87134   -2.27065  -39.91288 1.000 12.17022 ? 74  TRP E CZ3 1 
ATOM   1985 C CH2 . TRP C  1 76 ? 9.04840   -3.64722  -39.70065 1.000 14.04188 ? 74  TRP E CH2 1 
ATOM   1986 N N   . CYS C  1 77 ? 5.68097   2.47310   -37.83645 1.000 7.82780  ? 75  CYS E N   1 
ATOM   1987 C CA  . CYS C  1 77 ? 5.43111   3.90445   -37.73809 1.000 8.34559  ? 75  CYS E CA  1 
ATOM   1988 C C   . CYS C  1 77 ? 5.29979   4.50148   -39.12704 1.000 7.78436  ? 75  CYS E C   1 
ATOM   1989 O O   . CYS C  1 77 ? 6.19513   4.32829   -39.96382 1.000 9.08163  ? 75  CYS E O   1 
ATOM   1990 C CB  . CYS C  1 77 ? 6.59914   4.60916   -37.04644 1.000 9.37208  ? 75  CYS E CB  1 
ATOM   1991 S SG  . CYS C  1 77 ? 7.03959   3.92114   -35.45186 1.000 9.95631  ? 75  CYS E SG  1 
ATOM   1992 N N   . TRP C  1 78 ? 4.21348   5.22833   -39.35763 1.000 8.33735  ? 76  TRP E N   1 
ATOM   1993 C CA  . TRP C  1 78 ? 4.05619   6.06535   -40.53750 1.000 9.78280  ? 76  TRP E CA  1 
ATOM   1994 C C   . TRP C  1 78 ? 4.13924   7.51006   -40.08197 1.000 8.95389  ? 76  TRP E C   1 
ATOM   1995 O O   . TRP C  1 78 ? 3.32847   7.95266   -39.25728 1.000 10.39552 ? 76  TRP E O   1 
ATOM   1996 C CB  . TRP C  1 78 ? 2.71191   5.84770   -41.23336 1.000 9.37154  ? 76  TRP E CB  1 
ATOM   1997 C CG  . TRP C  1 78 ? 2.50136   6.86665   -42.32098 1.000 10.45649 ? 76  TRP E CG  1 
ATOM   1998 C CD1 . TRP C  1 78 ? 1.94312   8.11453   -42.20766 1.000 11.28757 ? 76  TRP E CD1 1 
ATOM   1999 C CD2 . TRP C  1 78 ? 2.89964   6.73522   -43.68561 1.000 10.62908 ? 76  TRP E CD2 1 
ATOM   2000 N NE1 . TRP C  1 78 ? 1.95983   8.75496   -43.42518 1.000 12.35349 ? 76  TRP E NE1 1 
ATOM   2001 C CE2 . TRP C  1 78 ? 2.54561   7.92734   -44.34764 1.000 11.28633 ? 76  TRP E CE2 1 
ATOM   2002 C CE3 . TRP C  1 78 ? 3.52193   5.71683   -44.41734 1.000 10.29381 ? 76  TRP E CE3 1 
ATOM   2003 C CZ2 . TRP C  1 78 ? 2.79454   8.12937   -45.70373 1.000 10.77716 ? 76  TRP E CZ2 1 
ATOM   2004 C CZ3 . TRP C  1 78 ? 3.76031   5.91650   -45.76174 1.000 11.82061 ? 76  TRP E CZ3 1 
ATOM   2005 C CH2 . TRP C  1 78 ? 3.39364   7.11081   -46.39245 1.000 12.08784 ? 76  TRP E CH2 1 
ATOM   2006 N N   . ASP C  1 79 ? 5.09713   8.24595   -40.63837 1.000 9.88920  ? 77  ASP E N   1 
ATOM   2007 C CA  . ASP C  1 79 ? 5.28305   9.65536   -40.32628 1.000 11.00312 ? 77  ASP E CA  1 
ATOM   2008 C C   . ASP C  1 79 ? 5.47382   10.46801  -41.59824 1.000 13.29140 ? 77  ASP E C   1 
ATOM   2009 O O   . ASP C  1 79 ? 6.21585   11.45505  -41.60907 1.000 17.68847 ? 77  ASP E O   1 
ATOM   2010 C CB  . ASP C  1 79 ? 6.45565   9.84808   -39.36826 1.000 13.43896 ? 77  ASP E CB  1 
ATOM   2011 C CG  . ASP C  1 79 ? 6.27215   9.07386   -38.08101 1.000 13.84884 ? 77  ASP E CG  1 
ATOM   2012 O OD1 . ASP C  1 79 ? 5.38644   9.44394   -37.28317 1.000 12.53103 ? 77  ASP E OD1 1 
ATOM   2013 O OD2 . ASP C  1 79 ? 6.97568   8.06436   -37.88463 1.000 17.07270 ? 77  ASP E OD2 1 
ATOM   2014 N N   . GLY C  1 80 ? 4.83244   10.04813  -42.68461 1.000 10.89647 ? 78  GLY E N   1 
ATOM   2015 C CA  . GLY C  1 80 ? 4.81948   10.79617  -43.92106 1.000 14.97139 ? 78  GLY E CA  1 
ATOM   2016 C C   . GLY C  1 80 ? 5.72233   10.26431  -45.01367 1.000 13.05189 ? 78  GLY E C   1 
ATOM   2017 O O   . GLY C  1 80 ? 5.59192   10.70258  -46.16358 1.000 16.56705 ? 78  GLY E O   1 
ATOM   2018 N N   . ASN C  1 81 ? 6.62156   9.34099   -44.70208 1.000 12.56700 ? 79  ASN E N   1 
ATOM   2019 C CA  . ASN C  1 81 ? 7.63353   8.93339   -45.66967 1.000 15.53559 ? 79  ASN E CA  1 
ATOM   2020 C C   . ASN C  1 81 ? 7.99368   7.45818   -45.49675 1.000 16.84860 ? 79  ASN E C   1 
ATOM   2021 O O   . ASN C  1 81 ? 9.16273   7.08879   -45.36986 1.000 22.38072 ? 79  ASN E O   1 
ATOM   2022 C CB  . ASN C  1 81 ? 8.86222   9.83944   -45.57966 1.000 27.70634 ? 79  ASN E CB  1 
ATOM   2023 C CG  . ASN C  1 81 ? 9.76772   9.71456   -46.79053 1.000 44.82618 ? 79  ASN E CG  1 
ATOM   2024 O OD1 . ASN C  1 81 ? 9.29747   9.62765   -47.92659 1.000 52.00688 ? 79  ASN E OD1 1 
ATOM   2025 N ND2 . ASN C  1 81 ? 11.07397  9.69278   -46.55225 1.000 50.14341 ? 79  ASN E ND2 1 
ATOM   2026 N N   . GLY C  1 82 ? 6.98770   6.59230   -45.50314 1.000 13.45117 ? 80  GLY E N   1 
ATOM   2027 C CA  . GLY C  1 82 ? 7.21131   5.16584   -45.43344 1.000 11.16580 ? 80  GLY E CA  1 
ATOM   2028 C C   . GLY C  1 82 ? 7.08409   4.63597   -44.01518 1.000 10.58175 ? 80  GLY E C   1 
ATOM   2029 O O   . GLY C  1 82 ? 7.12122   5.37881   -43.03001 1.000 12.94717 ? 80  GLY E O   1 
ATOM   2030 N N   . TRP C  1 83 ? 6.93561   3.32136   -43.91282 1.000 9.53117  ? 81  TRP E N   1 
ATOM   2031 C CA  . TRP C  1 83 ? 6.79891   2.65775   -42.62300 1.000 8.74216  ? 81  TRP E CA  1 
ATOM   2032 C C   . TRP C  1 83 ? 8.17195   2.30476   -42.07062 1.000 9.13684  ? 81  TRP E C   1 
ATOM   2033 O O   . TRP C  1 83 ? 9.00932   1.73824   -42.78341 1.000 11.68432 ? 81  TRP E O   1 
ATOM   2034 C CB  . TRP C  1 83 ? 5.97110   1.38780   -42.77971 1.000 8.52746  ? 81  TRP E CB  1 
ATOM   2035 C CG  . TRP C  1 83 ? 4.54114   1.68285   -43.08546 1.000 8.33109  ? 81  TRP E CG  1 
ATOM   2036 C CD1 . TRP C  1 83 ? 3.95655   1.76426   -44.31756 1.000 8.53490  ? 81  TRP E CD1 1 
ATOM   2037 C CD2 . TRP C  1 83 ? 3.51105   1.95994   -42.13580 1.000 8.52334  ? 81  TRP E CD2 1 
ATOM   2038 N NE1 . TRP C  1 83 ? 2.61776   2.06084   -44.19140 1.000 7.94825  ? 81  TRP E NE1 1 
ATOM   2039 C CE2 . TRP C  1 83 ? 2.32386   2.19286   -42.86059 1.000 7.87533  ? 81  TRP E CE2 1 
ATOM   2040 C CE3 . TRP C  1 83 ? 3.47388   2.02724   -40.74122 1.000 8.33571  ? 81  TRP E CE3 1 
ATOM   2041 C CZ2 . TRP C  1 83 ? 1.11572   2.47976   -42.23759 1.000 7.28778  ? 81  TRP E CZ2 1 
ATOM   2042 C CZ3 . TRP C  1 83 ? 2.27133   2.30477   -40.12541 1.000 8.64817  ? 81  TRP E CZ3 1 
ATOM   2043 C CH2 . TRP C  1 83 ? 1.10969   2.52855   -40.87052 1.000 8.51027  ? 81  TRP E CH2 1 
ATOM   2044 N N   . THR C  1 84 ? 8.39398   2.62231   -40.80018 1.000 8.89132  ? 82  THR E N   1 
ATOM   2045 C CA  . THR C  1 84 ? 9.65072   2.32923   -40.13206 1.000 9.56643  ? 82  THR E CA  1 
ATOM   2046 C C   . THR C  1 84 ? 9.35928   1.62309   -38.81977 1.000 9.74058  ? 82  THR E C   1 
ATOM   2047 O O   . THR C  1 84 ? 8.32865   1.86367   -38.18742 1.000 9.71076  ? 82  THR E O   1 
ATOM   2048 C CB  . THR C  1 84 ? 10.47144  3.60827   -39.85276 1.000 13.11119 ? 82  THR E CB  1 
ATOM   2049 O OG1 . THR C  1 84 ? 9.77372   4.44527   -38.92060 1.000 15.09665 ? 82  THR E OG1 1 
ATOM   2050 C CG2 . THR C  1 84 ? 10.72299  4.38865   -41.14781 1.000 13.35398 ? 82  THR E CG2 1 
ATOM   2051 N N   . LYS C  1 85 ? 10.26725  0.75152   -38.40765 1.000 10.07217 ? 83  LYS E N   1 
ATOM   2052 C CA  . LYS C  1 85 ? 10.11213  0.09882   -37.11599 1.000 10.17814 ? 83  LYS E CA  1 
ATOM   2053 C C   . LYS C  1 85 ? 10.31047  1.10869   -35.99390 1.000 11.68053 ? 83  LYS E C   1 
ATOM   2054 O O   . LYS C  1 85 ? 11.28613  1.86414   -35.98733 1.000 16.14085 ? 83  LYS E O   1 
ATOM   2055 C CB  . LYS C  1 85 ? 11.12268  -1.03210  -36.96895 1.000 12.22017 ? 83  LYS E CB  1 
ATOM   2056 C CG  . LYS C  1 85 ? 10.95542  -1.79419  -35.67072 1.000 13.75305 ? 83  LYS E CG  1 
ATOM   2057 C CD  . LYS C  1 85 ? 12.08730  -2.77821  -35.44173 1.000 15.32840 ? 83  LYS E CD  1 
ATOM   2058 C CE  . LYS C  1 85 ? 11.89753  -3.53855  -34.13535 1.000 21.29557 ? 83  LYS E CE  1 
ATOM   2059 N NZ  . LYS C  1 85 ? 13.09788  -4.35132  -33.77879 1.000 18.11363 ? 83  LYS E NZ  1 
ATOM   2060 N N   . GLY C  1 86 ? 9.38538   1.11742   -35.03586 1.000 10.57953 ? 84  GLY E N   1 
ATOM   2061 C CA  . GLY C  1 86 ? 9.46162   2.02863   -33.91690 1.000 12.29609 ? 84  GLY E CA  1 
ATOM   2062 C C   . GLY C  1 86 ? 10.20338  1.44087   -32.73436 1.000 11.37171 ? 84  GLY E C   1 
ATOM   2063 O O   . GLY C  1 86 ? 10.59716  0.27744   -32.71066 1.000 11.44086 ? 84  GLY E O   1 
ATOM   2064 N N   . ALA C  1 87 ? 10.37225  2.28552   -31.71577 1.000 12.36833 ? 85  ALA E N   1 
ATOM   2065 C CA  . ALA C  1 87 ? 11.12445  1.91406   -30.52680 1.000 14.06696 ? 85  ALA E CA  1 
ATOM   2066 C C   . ALA C  1 87 ? 10.31893  1.10505   -29.51959 1.000 11.67999 ? 85  ALA E C   1 
ATOM   2067 O O   . ALA C  1 87 ? 10.89655  0.65896   -28.52557 1.000 14.19875 ? 85  ALA E O   1 
ATOM   2068 C CB  . ALA C  1 87 ? 11.68768  3.15998   -29.84047 1.000 18.69310 ? 85  ALA E CB  1 
ATOM   2069 N N   . TYR C  1 88 ? 9.01936   0.89425   -29.74220 1.000 9.66742  ? 86  TYR E N   1 
ATOM   2070 C CA  . TYR C  1 88 ? 8.21730   0.13699   -28.79070 1.000 9.22046  ? 86  TYR E CA  1 
ATOM   2071 C C   . TYR C  1 88 ? 8.86913   -1.20024  -28.50082 1.000 10.75683 ? 86  TYR E C   1 
ATOM   2072 O O   . TYR C  1 88 ? 9.26947   -1.92880  -29.41514 1.000 11.53935 ? 86  TYR E O   1 
ATOM   2073 C CB  . TYR C  1 88 ? 6.81797   -0.12012  -29.34034 1.000 9.00212  ? 86  TYR E CB  1 
ATOM   2074 C CG  . TYR C  1 88 ? 5.99420   -1.00403  -28.43017 1.000 7.76329  ? 86  TYR E CG  1 
ATOM   2075 C CD1 . TYR C  1 88 ? 5.24023   -0.44642  -27.41346 1.000 8.86821  ? 86  TYR E CD1 1 
ATOM   2076 C CD2 . TYR C  1 88 ? 5.98564   -2.38640  -28.57050 1.000 9.01620  ? 86  TYR E CD2 1 
ATOM   2077 C CE1 . TYR C  1 88 ? 4.48671   -1.23230  -26.56455 1.000 9.11913  ? 86  TYR E CE1 1 
ATOM   2078 C CE2 . TYR C  1 88 ? 5.23717   -3.17916  -27.72552 1.000 9.76109  ? 86  TYR E CE2 1 
ATOM   2079 C CZ  . TYR C  1 88 ? 4.48651   -2.59849  -26.72577 1.000 8.21217  ? 86  TYR E CZ  1 
ATOM   2080 O OH  . TYR C  1 88 ? 3.73733   -3.38544  -25.88116 1.000 9.61781  ? 86  TYR E OH  1 
ATOM   2081 N N   . THR C  1 89 ? 8.96981   -1.51669  -27.21807 1.000 11.57079 ? 87  THR E N   1 
ATOM   2082 C CA  . THR C  1 89 ? 9.40953   -2.82541  -26.78392 1.000 14.52118 ? 87  THR E CA  1 
ATOM   2083 C C   . THR C  1 89 ? 8.56831   -3.21778  -25.58633 1.000 15.86387 ? 87  THR E C   1 
ATOM   2084 O O   . THR C  1 89 ? 7.96352   -2.37521  -24.91815 1.000 14.45711 ? 87  THR E O   1 
ATOM   2085 C CB  . THR C  1 89 ? 10.89262  -2.85533  -26.36770 1.000 16.95937 ? 87  THR E CB  1 
ATOM   2086 O OG1 . THR C  1 89 ? 11.10199  -1.95190  -25.27201 1.000 18.63580 ? 87  THR E OG1 1 
ATOM   2087 C CG2 . THR C  1 89 ? 11.81158  -2.48980  -27.53505 1.000 17.91800 ? 87  THR E CG2 1 
ATOM   2088 N N   . ALA C  1 90 ? 8.54269   -4.51861  -25.32867 1.000 16.67423 ? 88  ALA E N   1 
ATOM   2089 C CA  . ALA C  1 90 ? 7.92892   -5.07021  -24.13480 1.000 24.95071 ? 88  ALA E CA  1 
ATOM   2090 C C   . ALA C  1 90 ? 8.60573   -6.40124  -23.85221 1.000 35.24499 ? 88  ALA E C   1 
ATOM   2091 O O   . ALA C  1 90 ? 9.18586   -7.02261  -24.74685 1.000 37.02054 ? 88  ALA E O   1 
ATOM   2092 C CB  . ALA C  1 90 ? 6.41533   -5.24471  -24.30750 1.000 16.59071 ? 88  ALA E CB  1 
ATOM   2093 N N   . THR C  1 91 ? 8.54962   -6.82521  -22.59361 1.000 33.68143 ? 89  THR E N   1 
ATOM   2094 C CA  . THR C  1 91 ? 9.13104   -8.09783  -22.17197 1.000 29.04815 ? 89  THR E CA  1 
ATOM   2095 C C   . THR C  1 91 ? 7.98380   -9.05521  -21.86394 1.000 38.16084 ? 89  THR E C   1 
ATOM   2096 O O   . THR C  1 91 ? 7.63511   -9.29684  -20.70767 1.000 44.18920 ? 89  THR E O   1 
ATOM   2097 C CB  . THR C  1 91 ? 10.06793  -7.90854  -20.97744 1.000 36.60235 ? 89  THR E CB  1 
ATOM   2098 O OG1 . THR C  1 91 ? 9.43642   -7.07493  -19.99710 1.000 42.84332 ? 89  THR E OG1 1 
ATOM   2099 C CG2 . THR C  1 91 ? 11.37371  -7.27072  -21.42831 1.000 36.21869 ? 89  THR E CG2 1 
ATOM   2100 N N   . ASN C  1 92 ? 7.39539   -9.60263  -22.92233 1.000 29.07032 ? 90  ASN E N   1 
ATOM   2101 C CA  . ASN C  1 92 ? 6.26158   -10.50819 -22.79288 1.000 35.60660 ? 90  ASN E CA  1 
ATOM   2102 C C   . ASN C  1 92 ? 6.72385   -11.94438 -22.56389 1.000 33.55231 ? 90  ASN E C   1 
ATOM   2103 O O   . ASN C  1 92 ? 6.08293   -12.70066 -21.83324 1.000 33.20613 ? 90  ASN E O   1 
ATOM   2104 C CB  . ASN C  1 92 ? 5.37542   -10.42955 -24.03833 1.000 26.51967 ? 90  ASN E CB  1 
ATOM   2105 C CG  . ASN C  1 92 ? 4.79723   -9.04114  -24.25782 1.000 32.28456 ? 90  ASN E CG  1 
ATOM   2106 O OD1 . ASN C  1 92 ? 4.25779   -8.42550  -23.33479 1.000 22.17540 ? 90  ASN E OD1 1 
ATOM   2107 N ND2 . ASN C  1 92 ? 4.91510   -8.53715  -25.48327 1.000 16.04979 ? 90  ASN E ND2 1 
ATOM   2108 N N   . ALA D  1 3  ? -34.49181 -18.70788 -3.26165  1.000 50.73998 ? 1   ALA F N   1 
ATOM   2109 C CA  . ALA D  1 3  ? -33.79873 -17.82367 -2.32953  1.000 62.79555 ? 1   ALA F CA  1 
ATOM   2110 C C   . ALA D  1 3  ? -34.29327 -16.38176 -2.45971  1.000 44.07158 ? 1   ALA F C   1 
ATOM   2111 O O   . ALA D  1 3  ? -34.29627 -15.81864 -3.55718  1.000 34.26847 ? 1   ALA F O   1 
ATOM   2112 C CB  . ALA D  1 3  ? -32.29246 -17.89627 -2.55456  1.000 53.37557 ? 1   ALA F CB  1 
ATOM   2113 N N   . SER D  1 4  ? -34.71356 -15.78986 -1.34000  1.000 35.98633 ? 2   SER F N   1 
ATOM   2114 C CA  . SER D  1 4  ? -35.20683 -14.41570 -1.32509  1.000 22.49038 ? 2   SER F CA  1 
ATOM   2115 C C   . SER D  1 4  ? -34.03846 -13.45286 -1.14071  1.000 15.23069 ? 2   SER F C   1 
ATOM   2116 O O   . SER D  1 4  ? -33.33223 -13.50339 -0.12671  1.000 17.11015 ? 2   SER F O   1 
ATOM   2117 C CB  . SER D  1 4  ? -36.25968 -14.21083 -0.23610  1.000 27.27036 ? 2   SER F CB  1 
ATOM   2118 O OG  . SER D  1 4  ? -37.55892 -14.54564 -0.70549  1.000 22.13345 ? 2   SER F OG  1 
ATOM   2119 N N   . VAL D  1 5  ? -33.84684 -12.57436 -2.12424  1.000 12.99690 ? 3   VAL F N   1 
ATOM   2120 C CA  . VAL D  1 5  ? -32.75160 -11.61451 -2.07479  1.000 11.10068 ? 3   VAL F CA  1 
ATOM   2121 C C   . VAL D  1 5  ? -32.96099 -10.63686 -0.92253  1.000 10.34531 ? 3   VAL F C   1 
ATOM   2122 O O   . VAL D  1 5  ? -34.06278 -10.48223 -0.38383  1.000 13.07906 ? 3   VAL F O   1 
ATOM   2123 C CB  . VAL D  1 5  ? -32.60473 -10.87844 -3.41736  1.000 12.29121 ? 3   VAL F CB  1 
ATOM   2124 C CG1 . VAL D  1 5  ? -32.33130 -11.86972 -4.54555  1.000 12.49894 ? 3   VAL F CG1 1 
ATOM   2125 C CG2 . VAL D  1 5  ? -33.84796 -10.03785 -3.72157  1.000 13.55010 ? 3   VAL F CG2 1 
ATOM   2126 N N   A GLN D  1 6  ? -31.86868 -9.99559  -0.52169  0.550 9.94478  ? 4   GLN F N   1 
ATOM   2127 N N   B GLN D  1 6  ? -31.88768 -9.93635  -0.55833  0.450 9.98334  ? 4   GLN F N   1 
ATOM   2128 C CA  A GLN D  1 6  ? -31.87319 -8.97499  0.51299   0.550 10.67038 ? 4   GLN F CA  1 
ATOM   2129 C CA  B GLN D  1 6  ? -31.92798 -8.97000  0.53401   0.450 10.75895 ? 4   GLN F CA  1 
ATOM   2130 C C   A GLN D  1 6  ? -31.42142 -7.66897  -0.12483  0.550 8.57530  ? 4   GLN F C   1 
ATOM   2131 C C   B GLN D  1 6  ? -31.30976 -7.65873  0.07564   0.450 8.03158  ? 4   GLN F C   1 
ATOM   2132 O O   A GLN D  1 6  ? -30.54413 -7.66872  -0.99658  0.550 7.65047  ? 4   GLN F O   1 
ATOM   2133 O O   B GLN D  1 6  ? -30.18518 -7.64850  -0.43853  0.450 7.68592  ? 4   GLN F O   1 
ATOM   2134 C CB  A GLN D  1 6  ? -30.92163 -9.37484  1.65215   0.550 10.65959 ? 4   GLN F CB  1 
ATOM   2135 C CB  B GLN D  1 6  ? -31.18612 -9.49958  1.75956   0.450 11.72153 ? 4   GLN F CB  1 
ATOM   2136 C CG  A GLN D  1 6  ? -30.98371 -8.48419  2.89042   0.550 11.59477 ? 4   GLN F CG  1 
ATOM   2137 C CG  B GLN D  1 6  ? -31.76379 -10.79089 2.29493   0.450 16.25567 ? 4   GLN F CG  1 
ATOM   2138 C CD  A GLN D  1 6  ? -29.73148 -7.64853  3.06564   0.550 10.62871 ? 4   GLN F CD  1 
ATOM   2139 C CD  B GLN D  1 6  ? -31.19813 -11.15640 3.64536   0.450 18.47606 ? 4   GLN F CD  1 
ATOM   2140 O OE1 A GLN D  1 6  ? -28.62754 -8.09807  2.76238   0.550 10.99491 ? 4   GLN F OE1 1 
ATOM   2141 O OE1 B GLN D  1 6  ? -30.41839 -10.40353 4.22371   0.450 15.71648 ? 4   GLN F OE1 1 
ATOM   2142 N NE2 A GLN D  1 6  ? -29.89827 -6.41950  3.53794   0.550 12.49010 ? 4   GLN F NE2 1 
ATOM   2143 N NE2 B GLN D  1 6  ? -31.58835 -12.31574 4.15953   0.450 17.46482 ? 4   GLN F NE2 1 
ATOM   2144 N N   . THR D  1 7  ? -32.03666 -6.55845  0.27403   1.000 7.94145  ? 5   THR F N   1 
ATOM   2145 C CA  . THR D  1 7  ? -31.65737 -5.26759  -0.26982  1.000 7.37799  ? 5   THR F CA  1 
ATOM   2146 C C   . THR D  1 7  ? -31.35596 -4.25691  0.82521   1.000 6.83285  ? 5   THR F C   1 
ATOM   2147 O O   . THR D  1 7  ? -31.74027 -4.41146  1.98650   1.000 7.44713  ? 5   THR F O   1 
ATOM   2148 C CB  . THR D  1 7  ? -32.72296 -4.67967  -1.21756  1.000 7.03376  ? 5   THR F CB  1 
ATOM   2149 O OG1 . THR D  1 7  ? -33.86914 -4.26788  -0.46919  1.000 8.38368  ? 5   THR F OG1 1 
ATOM   2150 C CG2 . THR D  1 7  ? -33.13868 -5.68185  -2.28571  1.000 9.74673  ? 5   THR F CG2 1 
ATOM   2151 N N   . ALA D  1 8  ? -30.67682 -3.19967  0.40779   1.000 6.47980  ? 6   ALA F N   1 
ATOM   2152 C CA  . ALA D  1 8  ? -30.45179 -2.01588  1.21250   1.000 6.97996  ? 6   ALA F CA  1 
ATOM   2153 C C   . ALA D  1 8  ? -30.54178 -0.82826  0.27172   1.000 6.29562  ? 6   ALA F C   1 
ATOM   2154 O O   . ALA D  1 8  ? -30.18190 -0.93836  -0.90618  1.000 8.24903  ? 6   ALA F O   1 
ATOM   2155 C CB  . ALA D  1 8  ? -29.07176 -2.06300  1.87437   1.000 8.07583  ? 6   ALA F CB  1 
ATOM   2156 N N   . ALA D  1 9  ? -31.02439 0.30417   0.77796   1.000 6.47256  ? 7   ALA F N   1 
ATOM   2157 C CA  . ALA D  1 9  ? -31.28223 1.45081   -0.08213  1.000 6.47200  ? 7   ALA F CA  1 
ATOM   2158 C C   . ALA D  1 9  ? -30.81610 2.73696   0.58403   1.000 6.65269  ? 7   ALA F C   1 
ATOM   2159 O O   . ALA D  1 9  ? -30.88258 2.88057   1.81206   1.000 7.10377  ? 7   ALA F O   1 
ATOM   2160 C CB  . ALA D  1 9  ? -32.77288 1.57380   -0.43438  1.000 8.69839  ? 7   ALA F CB  1 
ATOM   2161 N N   . THR D  1 10 ? -30.37579 3.68376   -0.24377  1.000 6.56433  ? 8   THR F N   1 
ATOM   2162 C CA  . THR D  1 10 ? -30.03742 5.02082   0.21758   1.000 7.15578  ? 8   THR F CA  1 
ATOM   2163 C C   . THR D  1 10 ? -30.44217 6.01610   -0.86193  1.000 6.03757  ? 8   THR F C   1 
ATOM   2164 O O   . THR D  1 10 ? -30.62647 5.64934   -2.02562  1.000 7.66698  ? 8   THR F O   1 
ATOM   2165 C CB  . THR D  1 10 ? -28.54498 5.12557   0.58650   1.000 7.61597  ? 8   THR F CB  1 
ATOM   2166 O OG1 . THR D  1 10 ? -28.31489 6.31100   1.35212   1.000 8.75078  ? 8   THR F OG1 1 
ATOM   2167 C CG2 . THR D  1 10 ? -27.65513 5.17287   -0.65030  1.000 8.89823  ? 8   THR F CG2 1 
ATOM   2168 N N   . SER D  1 11 ? -30.60860 7.27802   -0.47064  1.000 6.80536  ? 9   SER F N   1 
ATOM   2169 C CA  . SER D  1 11 ? -30.98685 8.30904   -1.42460  1.000 6.87389  ? 9   SER F CA  1 
ATOM   2170 C C   . SER D  1 11 ? -30.43937 9.64938   -0.96183  1.000 7.66068  ? 9   SER F C   1 
ATOM   2171 O O   . SER D  1 11 ? -30.12362 9.83199   0.21426   1.000 7.83422  ? 9   SER F O   1 
ATOM   2172 C CB  . SER D  1 11 ? -32.50683 8.38844   -1.59691  1.000 7.42627  ? 9   SER F CB  1 
ATOM   2173 O OG  . SER D  1 11 ? -33.14845 8.70029   -0.36667  1.000 7.69569  ? 9   SER F OG  1 
ATOM   2174 N N   . TRP D  1 12 ? -30.34636 10.59545  -1.89373  1.000 7.33609  ? 10  TRP F N   1 
ATOM   2175 C CA  . TRP D  1 12 ? -29.84069 11.91529  -1.54892  1.000 8.47499  ? 10  TRP F CA  1 
ATOM   2176 C C   . TRP D  1 12 ? -30.42846 12.97014  -2.47072  1.000 8.46552  ? 10  TRP F C   1 
ATOM   2177 O O   . TRP D  1 12 ? -30.82167 12.69408  -3.60744  1.000 9.17171  ? 10  TRP F O   1 
ATOM   2178 C CB  . TRP D  1 12 ? -28.30811 11.97761  -1.56203  1.000 8.68971  ? 10  TRP F CB  1 
ATOM   2179 C CG  . TRP D  1 12 ? -27.63795 11.69081  -2.87348  1.000 8.31118  ? 10  TRP F CG  1 
ATOM   2180 C CD1 . TRP D  1 12 ? -27.27734 12.60120  -3.82380  1.000 9.44580  ? 10  TRP F CD1 1 
ATOM   2181 C CD2 . TRP D  1 12 ? -27.19115 10.41482  -3.35447  1.000 8.38921  ? 10  TRP F CD2 1 
ATOM   2182 N NE1 . TRP D  1 12 ? -26.64381 11.97387  -4.86891  1.000 9.45685  ? 10  TRP F NE1 1 
ATOM   2183 C CE2 . TRP D  1 12 ? -26.57561 10.63162  -4.60261  1.000 8.17667  ? 10  TRP F CE2 1 
ATOM   2184 C CE3 . TRP D  1 12 ? -27.24534 9.11262   -2.84816  1.000 9.18949  ? 10  TRP F CE3 1 
ATOM   2185 C CZ2 . TRP D  1 12 ? -26.02492 9.59649   -5.35425  1.000 9.23448  ? 10  TRP F CZ2 1 
ATOM   2186 C CZ3 . TRP D  1 12 ? -26.70292 8.08470   -3.59686  1.000 9.44275  ? 10  TRP F CZ3 1 
ATOM   2187 C CH2 . TRP D  1 12 ? -26.09850 8.33244   -4.83539  1.000 8.66177  ? 10  TRP F CH2 1 
ATOM   2188 N N   . GLY D  1 13 ? -30.45672 14.19841  -1.96284  1.000 10.23999 ? 11  GLY F N   1 
ATOM   2189 C CA  . GLY D  1 13 ? -30.97401 15.32494  -2.70096  1.000 11.43409 ? 11  GLY F CA  1 
ATOM   2190 C C   . GLY D  1 13 ? -32.48710 15.28176  -2.83093  1.000 11.91486 ? 11  GLY F C   1 
ATOM   2191 O O   . GLY D  1 13 ? -33.19564 14.55947  -2.11758  1.000 13.47545 ? 11  GLY F O   1 
ATOM   2192 N N   . THR D  1 14 ? -32.98455 16.09615  -3.76055  1.000 12.77227 ? 12  THR F N   1 
ATOM   2193 C CA  . THR D  1 14 ? -34.41766 16.23803  -3.97199  1.000 13.78379 ? 12  THR F CA  1 
ATOM   2194 C C   . THR D  1 14 ? -34.88901 15.68031  -5.30403  1.000 13.60326 ? 12  THR F C   1 
ATOM   2195 O O   . THR D  1 14 ? -36.10184 15.60504  -5.52478  1.000 15.14210 ? 12  THR F O   1 
ATOM   2196 C CB  . THR D  1 14 ? -34.83800 17.71363  -3.86785  1.000 15.90998 ? 12  THR F CB  1 
ATOM   2197 O OG1 . THR D  1 14 ? -34.10413 18.48460  -4.82466  1.000 17.48460 ? 12  THR F OG1 1 
ATOM   2198 C CG2 . THR D  1 14 ? -34.56200 18.25945  -2.46896  1.000 17.99795 ? 12  THR F CG2 1 
ATOM   2199 N N   . VAL D  1 15 ? -33.97346 15.30733  -6.19936  1.000 12.23680 ? 13  VAL F N   1 
ATOM   2200 C CA  . VAL D  1 15 ? -34.38538 14.71726  -7.47612  1.000 13.55880 ? 13  VAL F CA  1 
ATOM   2201 C C   . VAL D  1 15 ? -35.23780 13.46652  -7.29099  1.000 12.98282 ? 13  VAL F C   1 
ATOM   2202 O O   . VAL D  1 15 ? -36.31293 13.38045  -7.90716  1.000 12.74045 ? 13  VAL F O   1 
ATOM   2203 C CB  . VAL D  1 15 ? -33.17108 14.51883  -8.39788  1.000 13.69930 ? 13  VAL F CB  1 
ATOM   2204 C CG1 . VAL D  1 15 ? -33.59551 13.81521  -9.67344  1.000 15.33559 ? 13  VAL F CG1 1 
ATOM   2205 C CG2 . VAL D  1 15 ? -32.50867 15.85479  -8.71265  1.000 17.07344 ? 13  VAL F CG2 1 
ATOM   2206 N N   . PRO D  1 16 ? -34.83027 12.46421  -6.50395  1.000 10.60517 ? 14  PRO F N   1 
ATOM   2207 C CA  . PRO D  1 16 ? -33.55383 12.29172  -5.81614  1.000 9.48287  ? 14  PRO F CA  1 
ATOM   2208 C C   . PRO D  1 16 ? -32.66014 11.39529  -6.64248  1.000 8.53682  ? 14  PRO F C   1 
ATOM   2209 O O   . PRO D  1 16 ? -33.04418 10.91338  -7.70716  1.000 9.40418  ? 14  PRO F O   1 
ATOM   2210 C CB  . PRO D  1 16 ? -33.98413 11.54428  -4.55749  1.000 10.16163 ? 14  PRO F CB  1 
ATOM   2211 C CG  . PRO D  1 16 ? -34.98507 10.57003  -5.11175  1.000 10.04722 ? 14  PRO F CG  1 
ATOM   2212 C CD  . PRO D  1 16 ? -35.74174 11.35310  -6.18184  1.000 10.94704 ? 14  PRO F CD  1 
ATOM   2213 N N   . SER D  1 17 ? -31.45530 11.15406  -6.14746  1.000 8.62185  ? 15  SER F N   1 
ATOM   2214 C CA  . SER D  1 17 ? -30.70026 9.98258   -6.54563  1.000 7.36474  ? 15  SER F CA  1 
ATOM   2215 C C   . SER D  1 17 ? -30.98066 8.87870   -5.54160  1.000 6.89712  ? 15  SER F C   1 
ATOM   2216 O O   . SER D  1 17 ? -31.06221 9.13416   -4.33627  1.000 8.20921  ? 15  SER F O   1 
ATOM   2217 C CB  . SER D  1 17 ? -29.20128 10.27411  -6.56556  1.000 8.47568  ? 15  SER F CB  1 
ATOM   2218 O OG  . SER D  1 17 ? -28.83395 11.01776  -7.71553  1.000 10.96698 ? 15  SER F OG  1 
ATOM   2219 N N   . ILE D  1 18 ? -31.15918 7.65952   -6.04303  1.000 6.76303  ? 16  ILE F N   1 
ATOM   2220 C CA  . ILE D  1 18 ? -31.38203 6.48426   -5.21012  1.000 6.89520  ? 16  ILE F CA  1 
ATOM   2221 C C   . ILE D  1 18 ? -30.37540 5.42334   -5.61951  1.000 6.12066  ? 16  ILE F C   1 
ATOM   2222 O O   . ILE D  1 18 ? -30.06884 5.26899   -6.81040  1.000 6.64813  ? 16  ILE F O   1 
ATOM   2223 C CB  . ILE D  1 18 ? -32.81001 5.91089   -5.36828  1.000 7.04461  ? 16  ILE F CB  1 
ATOM   2224 C CG1 . ILE D  1 18 ? -33.87471 7.01024   -5.29227  1.000 7.76761  ? 16  ILE F CG1 1 
ATOM   2225 C CG2 . ILE D  1 18 ? -33.05329 4.80477   -4.33938  1.000 8.32405  ? 16  ILE F CG2 1 
ATOM   2226 C CD1 . ILE D  1 18 ? -35.26800 6.54945   -5.71309  1.000 9.77752  ? 16  ILE F CD1 1 
ATOM   2227 N N   . ARG D  1 19 ? -29.86042 4.68615   -4.64117  1.000 6.43069  ? 17  ARG F N   1 
ATOM   2228 C CA  . ARG D  1 19 ? -29.05316 3.51130   -4.91818  1.000 6.03267  ? 17  ARG F CA  1 
ATOM   2229 C C   . ARG D  1 19 ? -29.62895 2.35364   -4.13056  1.000 6.60877  ? 17  ARG F C   1 
ATOM   2230 O O   . ARG D  1 19 ? -29.88285 2.47977   -2.92653  1.000 7.13214  ? 17  ARG F O   1 
ATOM   2231 C CB  . ARG D  1 19 ? -27.58013 3.70885   -4.54622  1.000 6.99397  ? 17  ARG F CB  1 
ATOM   2232 C CG  . ARG D  1 19 ? -26.89211 4.84307   -5.28346  1.000 7.62606  ? 17  ARG F CG  1 
ATOM   2233 C CD  . ARG D  1 19 ? -26.73392 4.53693   -6.76516  1.000 7.38293  ? 17  ARG F CD  1 
ATOM   2234 N NE  . ARG D  1 19 ? -26.02515 5.59150   -7.48343  1.000 8.28587  ? 17  ARG F NE  1 
ATOM   2235 C CZ  . ARG D  1 19 ? -26.60046 6.62773   -8.07765  1.000 7.29531  ? 17  ARG F CZ  1 
ATOM   2236 N NH1 . ARG D  1 19 ? -27.91291 6.81056   -8.03910  1.000 8.93308  ? 17  ARG F NH1 1 
ATOM   2237 N NH2 . ARG D  1 19 ? -25.84066 7.51304   -8.71851  1.000 9.41191  ? 17  ARG F NH2 1 
ATOM   2238 N N   . VAL D  1 20 ? -29.85608 1.23832   -4.81279  1.000 6.24563  ? 18  VAL F N   1 
ATOM   2239 C CA  . VAL D  1 20 ? -30.38466 0.03090   -4.19361  1.000 6.23424  ? 18  VAL F CA  1 
ATOM   2240 C C   . VAL D  1 20 ? -29.36945 -1.07983  -4.40122  1.000 5.93565  ? 18  VAL F C   1 
ATOM   2241 O O   . VAL D  1 20 ? -28.98833 -1.36843  -5.54505  1.000 6.52531  ? 18  VAL F O   1 
ATOM   2242 C CB  . VAL D  1 20 ? -31.74589 -0.37332  -4.78568  1.000 6.87139  ? 18  VAL F CB  1 
ATOM   2243 C CG1 . VAL D  1 20 ? -32.26465 -1.64835  -4.11816  1.000 8.73161  ? 18  VAL F CG1 1 
ATOM   2244 C CG2 . VAL D  1 20 ? -32.75601 0.76104   -4.65384  1.000 7.90383  ? 18  VAL F CG2 1 
ATOM   2245 N N   . TYR D  1 21 ? -28.94419 -1.70340  -3.30362  1.000 6.06908  ? 19  TYR F N   1 
ATOM   2246 C CA  . TYR D  1 21 ? -27.95751 -2.77461  -3.30229  1.000 6.34948  ? 19  TYR F CA  1 
ATOM   2247 C C   . TYR D  1 21 ? -28.68276 -4.07625  -3.02659  1.000 6.85686  ? 19  TYR F C   1 
ATOM   2248 O O   . TYR D  1 21 ? -29.48050 -4.14384  -2.09306  1.000 7.55654  ? 19  TYR F O   1 
ATOM   2249 C CB  . TYR D  1 21 ? -26.89105 -2.52124  -2.22028  1.000 6.88098  ? 19  TYR F CB  1 
ATOM   2250 C CG  . TYR D  1 21 ? -26.21270 -1.20837  -2.48755  1.000 6.77396  ? 19  TYR F CG  1 
ATOM   2251 C CD1 . TYR D  1 21 ? -26.74033 -0.01530  -2.00860  1.000 7.48549  ? 19  TYR F CD1 1 
ATOM   2252 C CD2 . TYR D  1 21 ? -25.11142 -1.14306  -3.32727  1.000 7.61512  ? 19  TYR F CD2 1 
ATOM   2253 C CE1 . TYR D  1 21 ? -26.17654 1.19360   -2.32481  1.000 6.63446  ? 19  TYR F CE1 1 
ATOM   2254 C CE2 . TYR D  1 21 ? -24.53543 0.06558   -3.64528  1.000 7.81378  ? 19  TYR F CE2 1 
ATOM   2255 C CZ  . TYR D  1 21 ? -25.07816 1.23501   -3.14762  1.000 6.99416  ? 19  TYR F CZ  1 
ATOM   2256 O OH  . TYR D  1 21 ? -24.53190 2.44570   -3.48143  1.000 7.57748  ? 19  TYR F OH  1 
ATOM   2257 N N   . THR D  1 22 ? -28.41691 -5.10559  -3.82921  1.000 7.22667  ? 20  THR F N   1 
ATOM   2258 C CA  . THR D  1 22 ? -29.07911 -6.39375  -3.67475  1.000 6.87176  ? 20  THR F CA  1 
ATOM   2259 C C   . THR D  1 22 ? -28.03886 -7.47419  -3.45746  1.000 6.84622  ? 20  THR F C   1 
ATOM   2260 O O   . THR D  1 22 ? -27.14903 -7.66005  -4.29552  1.000 8.14734  ? 20  THR F O   1 
ATOM   2261 C CB  . THR D  1 22 ? -29.90892 -6.73139  -4.91013  1.000 7.73086  ? 20  THR F CB  1 
ATOM   2262 O OG1 . THR D  1 22 ? -30.90531 -5.72171  -5.09217  1.000 8.53814  ? 20  THR F OG1 1 
ATOM   2263 C CG2 . THR D  1 22 ? -30.59650 -8.07652  -4.73986  1.000 10.24158 ? 20  THR F CG2 1 
ATOM   2264 N N   . ALA D  1 23 ? -28.17843 -8.20141  -2.35826  1.000 7.60535  ? 21  ALA F N   1 
ATOM   2265 C CA  . ALA D  1 23 ? -27.38458 -9.39240  -2.10183  1.000 8.55691  ? 21  ALA F CA  1 
ATOM   2266 C C   . ALA D  1 23 ? -28.15754 -10.59457 -2.62733  1.000 8.42352  ? 21  ALA F C   1 
ATOM   2267 O O   . ALA D  1 23 ? -29.26847 -10.88122 -2.16631  1.000 10.60219 ? 21  ALA F O   1 
ATOM   2268 C CB  . ALA D  1 23 ? -27.10843 -9.53758  -0.60725  1.000 10.70962 ? 21  ALA F CB  1 
ATOM   2269 N N   . ASN D  1 24 ? -27.58459 -11.26958 -3.61584  1.000 9.91306  ? 22  ASN F N   1 
ATOM   2270 C CA  . ASN D  1 24 ? -28.23790 -12.38018 -4.29385  1.000 10.99489 ? 22  ASN F CA  1 
ATOM   2271 C C   . ASN D  1 24 ? -27.19348 -13.46382 -4.47629  1.000 9.88409  ? 22  ASN F C   1 
ATOM   2272 O O   . ASN D  1 24 ? -26.18994 -13.24192 -5.15667  1.000 10.89533 ? 22  ASN F O   1 
ATOM   2273 C CB  . ASN D  1 24 ? -28.76887 -11.91865 -5.65345  1.000 11.89621 ? 22  ASN F CB  1 
ATOM   2274 C CG  . ASN D  1 24 ? -29.50383 -13.01611 -6.40172  1.000 17.13623 ? 22  ASN F CG  1 
ATOM   2275 O OD1 . ASN D  1 24 ? -29.66669 -14.12790 -5.89878  1.000 24.33233 ? 22  ASN F OD1 1 
ATOM   2276 N ND2 . ASN D  1 24 ? -29.97222 -12.69893 -7.60091  1.000 17.25582 ? 22  ASN F ND2 1 
ATOM   2277 N N   . ASN D  1 25 ? -27.41198 -14.61234 -3.83984  1.000 11.03032 ? 23  ASN F N   1 
ATOM   2278 C CA  . ASN D  1 25 ? -26.50732 -15.75466 -3.96342  1.000 12.34476 ? 23  ASN F CA  1 
ATOM   2279 C C   . ASN D  1 25 ? -25.06029 -15.37034 -3.66833  1.000 13.29170 ? 23  ASN F C   1 
ATOM   2280 O O   . ASN D  1 25 ? -24.13315 -15.77272 -4.37220  1.000 13.41064 ? 23  ASN F O   1 
ATOM   2281 C CB  . ASN D  1 25 ? -26.63571 -16.43790 -5.32551  1.000 17.24799 ? 23  ASN F CB  1 
ATOM   2282 C CG  . ASN D  1 25 ? -27.89644 -17.27041 -5.44236  1.000 16.47259 ? 23  ASN F CG  1 
ATOM   2283 O OD1 . ASN D  1 25 ? -28.05617 -18.27226 -4.74757  1.000 29.37632 ? 23  ASN F OD1 1 
ATOM   2284 N ND2 . ASN D  1 25 ? -28.79776 -16.85887 -6.32433  1.000 30.64463 ? 23  ASN F ND2 1 
ATOM   2285 N N   . GLY D  1 26 ? -24.86813 -14.56397 -2.62730  1.000 11.13679 ? 24  GLY F N   1 
ATOM   2286 C CA  . GLY D  1 26 ? -23.53940 -14.22014 -2.17152  1.000 11.56793 ? 24  GLY F CA  1 
ATOM   2287 C C   . GLY D  1 26 ? -22.85717 -13.08208 -2.90094  1.000 11.16107 ? 24  GLY F C   1 
ATOM   2288 O O   . GLY D  1 26 ? -21.68782 -12.79472 -2.60187  1.000 11.30084 ? 24  GLY F O   1 
ATOM   2289 N N   . LYS D  1 27 ? -23.53305 -12.42512 -3.84042  1.000 10.54591 ? 25  LYS F N   1 
ATOM   2290 C CA  . LYS D  1 27 ? -22.97373 -11.29175 -4.56221  1.000 10.17046 ? 25  LYS F CA  1 
ATOM   2291 C C   . LYS D  1 27 ? -23.88307 -10.08316 -4.40723  1.000 8.63912  ? 25  LYS F C   1 
ATOM   2292 O O   . LYS D  1 27 ? -25.11155 -10.20544 -4.47714  1.000 10.30615 ? 25  LYS F O   1 
ATOM   2293 C CB  . LYS D  1 27 ? -22.83281 -11.61450 -6.04730  1.000 13.54715 ? 25  LYS F CB  1 
ATOM   2294 C CG  . LYS D  1 27 ? -21.91095 -12.79130 -6.32601  1.000 20.14652 ? 25  LYS F CG  1 
ATOM   2295 C CD  . LYS D  1 27 ? -21.37188 -12.76342 -7.74975  1.000 41.34284 ? 25  LYS F CD  1 
ATOM   2296 C CE  . LYS D  1 27 ? -20.44897 -13.94831 -8.00385  1.000 51.83776 ? 25  LYS F CE  1 
ATOM   2297 N NZ  . LYS D  1 27 ? -19.39241 -13.63814 -9.00978  1.000 52.50733 ? 25  LYS F NZ  1 
ATOM   2298 N N   . ILE D  1 28 ? -23.27937 -8.91529  -4.20750  1.000 8.40769  ? 26  ILE F N   1 
ATOM   2299 C CA  . ILE D  1 28 ? -24.01530 -7.66485  -4.07118  1.000 7.73249  ? 26  ILE F CA  1 
ATOM   2300 C C   . ILE D  1 28 ? -23.80163 -6.83313  -5.32504  1.000 7.34617  ? 26  ILE F C   1 
ATOM   2301 O O   . ILE D  1 28 ? -22.65660 -6.55849  -5.70672  1.000 9.32133  ? 26  ILE F O   1 
ATOM   2302 C CB  . ILE D  1 28 ? -23.58614 -6.87874  -2.82423  1.000 8.44715  ? 26  ILE F CB  1 
ATOM   2303 C CG1 . ILE D  1 28 ? -23.77053 -7.70703  -1.55767  1.000 10.23003 ? 26  ILE F CG1 1 
ATOM   2304 C CG2 . ILE D  1 28 ? -24.40687 -5.59528  -2.71129  1.000 9.98215  ? 26  ILE F CG2 1 
ATOM   2305 C CD1 . ILE D  1 28 ? -22.98457 -7.16971  -0.40057  1.000 12.09332 ? 26  ILE F CD1 1 
ATOM   2306 N N   . THR D  1 29 ? -24.89902 -6.41847  -5.95039  1.000 7.66173  ? 27  THR F N   1 
ATOM   2307 C CA  . THR D  1 29 ? -24.88176 -5.51451  -7.08959  1.000 7.85852  ? 27  THR F CA  1 
ATOM   2308 C C   . THR D  1 29 ? -25.74758 -4.29089  -6.79670  1.000 7.00190  ? 27  THR F C   1 
ATOM   2309 O O   . THR D  1 29 ? -26.42984 -4.21068  -5.77123  1.000 7.83793  ? 27  THR F O   1 
ATOM   2310 C CB  . THR D  1 29 ? -25.33622 -6.22249  -8.37113  1.000 9.37223  ? 27  THR F CB  1 
ATOM   2311 O OG1 . THR D  1 29 ? -26.62903 -6.78852  -8.16381  1.000 12.72427 ? 27  THR F OG1 1 
ATOM   2312 C CG2 . THR D  1 29 ? -24.36736 -7.34100  -8.74316  1.000 12.02981 ? 27  THR F CG2 1 
ATOM   2313 N N   . GLU D  1 30 ? -25.69614 -3.31900  -7.70270  1.000 6.82136  ? 28  GLU F N   1 
ATOM   2314 C CA  . GLU D  1 30 ? -26.22236 -1.98725  -7.43909  1.000 6.64588  ? 28  GLU F CA  1 
ATOM   2315 C C   . GLU D  1 30 ? -27.05928 -1.49791  -8.61017  1.000 6.76813  ? 28  GLU F C   1 
ATOM   2316 O O   . GLU D  1 30 ? -26.63561 -1.59849  -9.77042  1.000 7.57170  ? 28  GLU F O   1 
ATOM   2317 C CB  . GLU D  1 30 ? -25.06300 -1.01945  -7.20441  1.000 7.83840  ? 28  GLU F CB  1 
ATOM   2318 C CG  . GLU D  1 30 ? -25.42824 0.43423   -6.97915  1.000 7.91417  ? 28  GLU F CG  1 
ATOM   2319 C CD  . GLU D  1 30 ? -24.20945 1.34342   -7.03772  1.000 7.32888  ? 28  GLU F CD  1 
ATOM   2320 O OE1 . GLU D  1 30 ? -23.40531 1.17071   -7.97671  1.000 7.72246  ? 28  GLU F OE1 1 
ATOM   2321 O OE2 . GLU D  1 30 ? -24.05850 2.22603   -6.15828  1.000 8.29053  ? 28  GLU F OE2 1 
ATOM   2322 N N   . ARG D  1 31 ? -28.22761 -0.93814  -8.29916  1.000 7.29903  ? 29  ARG F N   1 
ATOM   2323 C CA  . ARG D  1 31 ? -29.06568 -0.26031  -9.27425  1.000 7.03444  ? 29  ARG F CA  1 
ATOM   2324 C C   . ARG D  1 31 ? -29.23285 1.19498   -8.86613  1.000 6.76350  ? 29  ARG F C   1 
ATOM   2325 O O   . ARG D  1 31 ? -29.28873 1.52092   -7.67072  1.000 7.57219  ? 29  ARG F O   1 
ATOM   2326 C CB  . ARG D  1 31 ? -30.42659 -0.94714  -9.41491  1.000 8.01310  ? 29  ARG F CB  1 
ATOM   2327 C CG  . ARG D  1 31 ? -30.32911 -2.35602  -9.97297  1.000 8.34730  ? 29  ARG F CG  1 
ATOM   2328 C CD  . ARG D  1 31 ? -30.13369 -2.35380  -11.48186 1.000 8.56982  ? 29  ARG F CD  1 
ATOM   2329 N NE  . ARG D  1 31 ? -31.40288 -2.14544  -12.16959 1.000 9.16784  ? 29  ARG F NE  1 
ATOM   2330 C CZ  . ARG D  1 31 ? -31.52726 -1.97206  -13.47982 1.000 9.36280  ? 29  ARG F CZ  1 
ATOM   2331 N NH1 . ARG D  1 31 ? -30.47115 -1.91835  -14.27493 1.000 11.22112 ? 29  ARG F NH1 1 
ATOM   2332 N NH2 . ARG D  1 31 ? -32.74420 -1.84119  -14.00460 1.000 10.43912 ? 29  ARG F NH2 1 
ATOM   2333 N N   . CYS D  1 32 ? -29.31437 2.06165   -9.86969  1.000 6.90894  ? 30  CYS F N   1 
ATOM   2334 C CA  . CYS D  1 32 ? -29.19325 3.49505   -9.68075  1.000 6.58068  ? 30  CYS F CA  1 
ATOM   2335 C C   . CYS D  1 32 ? -30.35675 4.21216   -10.33875 1.000 7.60462  ? 30  CYS F C   1 
ATOM   2336 O O   . CYS D  1 32 ? -30.75334 3.86766   -11.45744 1.000 7.79874  ? 30  CYS F O   1 
ATOM   2337 C CB  . CYS D  1 32 ? -27.92773 4.01982   -10.34395 1.000 8.28204  ? 30  CYS F CB  1 
ATOM   2338 S SG  . CYS D  1 32 ? -26.41711 3.15602   -9.90893  1.000 8.45457  ? 30  CYS F SG  1 
ATOM   2339 N N   . TRP D  1 33 ? -30.84580 5.25369   -9.66903  1.000 7.47002  ? 31  TRP F N   1 
ATOM   2340 C CA  . TRP D  1 33 ? -31.85571 6.16409   -10.18961 1.000 7.60988  ? 31  TRP F CA  1 
ATOM   2341 C C   . TRP D  1 33 ? -31.33930 7.57140   -9.96589  1.000 7.95172  ? 31  TRP F C   1 
ATOM   2342 O O   . TRP D  1 33 ? -30.95498 7.91538   -8.84753  1.000 8.39954  ? 31  TRP F O   1 
ATOM   2343 C CB  . TRP D  1 33 ? -33.16824 6.00497   -9.41297  1.000 8.29478  ? 31  TRP F CB  1 
ATOM   2344 C CG  . TRP D  1 33 ? -34.24050 7.00467   -9.77465  1.000 9.02948  ? 31  TRP F CG  1 
ATOM   2345 C CD1 . TRP D  1 33 ? -34.48580 8.22425   -9.18423  1.000 9.35252  ? 31  TRP F CD1 1 
ATOM   2346 C CD2 . TRP D  1 33 ? -35.22449 6.85324   -10.80058 1.000 8.93406  ? 31  TRP F CD2 1 
ATOM   2347 N NE1 . TRP D  1 33 ? -35.56258 8.83279   -9.79374  1.000 10.73290 ? 31  TRP F NE1 1 
ATOM   2348 C CE2 . TRP D  1 33 ? -36.03256 8.01050   -10.78573 1.000 10.07627 ? 31  TRP F CE2 1 
ATOM   2349 C CE3 . TRP D  1 33 ? -35.50693 5.84930   -11.72682 1.000 9.51681  ? 31  TRP F CE3 1 
ATOM   2350 C CZ2 . TRP D  1 33 ? -37.09791 8.19169   -11.67296 1.000 10.53765 ? 31  TRP F CZ2 1 
ATOM   2351 C CZ3 . TRP D  1 33 ? -36.57868 6.02823   -12.59441 1.000 10.09960 ? 31  TRP F CZ3 1 
ATOM   2352 C CH2 . TRP D  1 33 ? -37.35203 7.19045   -12.56471 1.000 11.01945 ? 31  TRP F CH2 1 
ATOM   2353 N N   . ASP D  1 34 ? -31.30996 8.38119   -11.02746 1.000 8.58157  ? 32  ASP F N   1 
ATOM   2354 C CA  . ASP D  1 34 ? -30.97339 9.79621   -10.90890 1.000 9.96750  ? 32  ASP F CA  1 
ATOM   2355 C C   . ASP D  1 34 ? -32.06743 10.66874  -11.51220 1.000 11.25399 ? 32  ASP F C   1 
ATOM   2356 O O   . ASP D  1 34 ? -31.78556 11.78802  -11.95957 1.000 14.81733 ? 32  ASP F O   1 
ATOM   2357 C CB  . ASP D  1 34 ? -29.62772 10.13654  -11.56050 1.000 10.93113 ? 32  ASP F CB  1 
ATOM   2358 C CG  . ASP D  1 34 ? -28.45413 9.38082   -10.95583 1.000 11.93793 ? 32  ASP F CG  1 
ATOM   2359 O OD1 . ASP D  1 34 ? -28.32947 9.27662   -9.70940  1.000 11.52070 ? 32  ASP F OD1 1 
ATOM   2360 O OD2 . ASP D  1 34 ? -27.62032 8.90550   -11.75958 1.000 16.24565 ? 32  ASP F OD2 1 
ATOM   2361 N N   . GLY D  1 35 ? -33.29776 10.16808  -11.56675 1.000 10.73722 ? 33  GLY F N   1 
ATOM   2362 C CA  . GLY D  1 35 ? -34.43801 10.92865  -12.03142 1.000 13.40187 ? 33  GLY F CA  1 
ATOM   2363 C C   . GLY D  1 35 ? -34.98185 10.50232  -13.37446 1.000 12.47904 ? 33  GLY F C   1 
ATOM   2364 O O   . GLY D  1 35 ? -36.08324 10.94082  -13.73822 1.000 16.22556 ? 33  GLY F O   1 
ATOM   2365 N N   . LYS D  1 36 ? -34.27004 9.65392   -14.11511 1.000 12.11687 ? 34  LYS F N   1 
ATOM   2366 C CA  . LYS D  1 36 ? -34.57432 9.40140   -15.52429 1.000 15.25991 ? 34  LYS F CA  1 
ATOM   2367 C C   . LYS D  1 36 ? -34.35930 7.93463   -15.89390 1.000 14.59277 ? 34  LYS F C   1 
ATOM   2368 O O   . LYS D  1 36 ? -33.80280 7.62367   -16.95233 1.000 18.96682 ? 34  LYS F O   1 
ATOM   2369 C CB  . LYS D  1 36 ? -33.73648 10.29657  -16.44245 1.000 20.17908 ? 34  LYS F CB  1 
ATOM   2370 C CG  . LYS D  1 36 ? -33.89682 11.79950  -16.22074 1.000 23.05746 ? 34  LYS F CG  1 
ATOM   2371 C CD  . LYS D  1 36 ? -35.25471 12.30023  -16.69193 1.000 33.32268 ? 34  LYS F CD  1 
ATOM   2372 C CE  . LYS D  1 36 ? -35.45654 13.77468  -16.35748 1.000 35.25564 ? 34  LYS F CE  1 
ATOM   2373 N NZ  . LYS D  1 36 ? -34.53432 14.66938  -17.11315 1.000 52.38215 ? 34  LYS F NZ  1 
ATOM   2374 N N   . GLY D  1 37 ? -34.79152 7.01682   -15.04581 1.000 11.73327 ? 35  GLY F N   1 
ATOM   2375 C CA  . GLY D  1 37 ? -34.71412 5.60027   -15.34835 1.000 9.92077  ? 35  GLY F CA  1 
ATOM   2376 C C   . GLY D  1 37 ? -33.65073 4.89659   -14.51713 1.000 9.10676  ? 35  GLY F C   1 
ATOM   2377 O O   . GLY D  1 37 ? -32.62640 5.48126   -14.14434 1.000 11.18594 ? 35  GLY F O   1 
ATOM   2378 N N   . TRP D  1 38 ? -33.89505 3.62058   -14.22613 1.000 8.25887  ? 36  TRP F N   1 
ATOM   2379 C CA  . TRP D  1 38 ? -32.95014 2.81078   -13.46828 1.000 8.10126  ? 36  TRP F CA  1 
ATOM   2380 C C   . TRP D  1 38 ? -31.87511 2.23540   -14.37503 1.000 7.43715  ? 36  TRP F C   1 
ATOM   2381 O O   . TRP D  1 38 ? -32.14602 1.83419   -15.51516 1.000 9.37748  ? 36  TRP F O   1 
ATOM   2382 C CB  . TRP D  1 38 ? -33.67475 1.65988   -12.77020 1.000 8.00234  ? 36  TRP F CB  1 
ATOM   2383 C CG  . TRP D  1 38 ? -34.54854 2.12659   -11.63727 1.000 8.10797  ? 36  TRP F CG  1 
ATOM   2384 C CD1 . TRP D  1 38 ? -35.86700 2.48169   -11.70451 1.000 7.68926  ? 36  TRP F CD1 1 
ATOM   2385 C CD2 . TRP D  1 38 ? -34.15044 2.32092   -10.27539 1.000 7.13405  ? 36  TRP F CD2 1 
ATOM   2386 N NE1 . TRP D  1 38 ? -36.31846 2.87606   -10.46771 1.000 7.48749  ? 36  TRP F NE1 1 
ATOM   2387 C CE2 . TRP D  1 38 ? -35.28371 2.78604   -9.57055  1.000 7.52562  ? 36  TRP F CE2 1 
ATOM   2388 C CE3 . TRP D  1 38 ? -32.95146 2.13794   -9.58445  1.000 7.07661  ? 36  TRP F CE3 1 
ATOM   2389 C CZ2 . TRP D  1 38 ? -35.25094 3.06610   -8.20793  1.000 7.01821  ? 36  TRP F CZ2 1 
ATOM   2390 C CZ3 . TRP D  1 38 ? -32.91675 2.42184   -8.23840  1.000 7.65136  ? 36  TRP F CZ3 1 
ATOM   2391 C CH2 . TRP D  1 38 ? -34.05717 2.88153   -7.55966  1.000 7.07729  ? 36  TRP F CH2 1 
ATOM   2392 N N   . TYR D  1 39 ? -30.65829 2.15667   -13.84533 1.000 8.08425  ? 37  TYR F N   1 
ATOM   2393 C CA  . TYR D  1 39 ? -29.53394 1.59628   -14.58602 1.000 8.23071  ? 37  TYR F CA  1 
ATOM   2394 C C   . TYR D  1 39 ? -28.59777 0.91273   -13.59384 1.000 7.48897  ? 37  TYR F C   1 
ATOM   2395 O O   . TYR D  1 39 ? -28.71484 1.08510   -12.37767 1.000 9.34866  ? 37  TYR F O   1 
ATOM   2396 C CB  . TYR D  1 39 ? -28.81622 2.65582   -15.44030 1.000 10.14070 ? 37  TYR F CB  1 
ATOM   2397 C CG  . TYR D  1 39 ? -28.18521 3.75353   -14.63213 1.000 9.12592  ? 37  TYR F CG  1 
ATOM   2398 C CD1 . TYR D  1 39 ? -28.91063 4.87067   -14.26033 1.000 9.57240  ? 37  TYR F CD1 1 
ATOM   2399 C CD2 . TYR D  1 39 ? -26.86240 3.66396   -14.22455 1.000 9.54210  ? 37  TYR F CD2 1 
ATOM   2400 C CE1 . TYR D  1 39 ? -28.33931 5.87250   -13.51066 1.000 10.51310 ? 37  TYR F CE1 1 
ATOM   2401 C CE2 . TYR D  1 39 ? -26.28012 4.66648   -13.47635 1.000 10.37996 ? 37  TYR F CE2 1 
ATOM   2402 C CZ  . TYR D  1 39 ? -27.02083 5.76325   -13.12196 1.000 10.78292 ? 37  TYR F CZ  1 
ATOM   2403 O OH  . TYR D  1 39 ? -26.42982 6.75298   -12.37281 1.000 12.81849 ? 37  TYR F OH  1 
ATOM   2404 N N   . THR D  1 40 ? -27.65508 0.13741   -14.11319 1.000 8.78504  ? 38  THR F N   1 
ATOM   2405 C CA  . THR D  1 40 ? -26.76386 -0.64005  -13.26443 1.000 8.26129  ? 38  THR F CA  1 
ATOM   2406 C C   . THR D  1 40 ? -25.52844 0.16584   -12.89390 1.000 7.69774  ? 38  THR F C   1 
ATOM   2407 O O   . THR D  1 40 ? -24.91576 0.80840   -13.75197 1.000 9.27339  ? 38  THR F O   1 
ATOM   2408 C CB  . THR D  1 40 ? -26.40975 -1.94605  -13.96724 1.000 9.80636  ? 38  THR F CB  1 
ATOM   2409 O OG1 . THR D  1 40 ? -27.61052 -2.72015  -14.08321 1.000 10.52503 ? 38  THR F OG1 1 
ATOM   2410 C CG2 . THR D  1 40 ? -25.34770 -2.72851  -13.19272 1.000 10.90019 ? 38  THR F CG2 1 
ATOM   2411 N N   . GLY D  1 41 ? -25.18972 0.15686   -11.60316 1.000 8.30864  ? 39  GLY F N   1 
ATOM   2412 C CA  . GLY D  1 41 ? -24.04191 0.88698   -11.11260 1.000 8.90044  ? 39  GLY F CA  1 
ATOM   2413 C C   . GLY D  1 41 ? -22.78200 0.03973   -11.05242 1.000 7.44488  ? 39  GLY F C   1 
ATOM   2414 O O   . GLY D  1 41 ? -22.77940 -1.16216  -11.29521 1.000 8.59084  ? 39  GLY F O   1 
ATOM   2415 N N   . ALA D  1 42 ? -21.68451 0.70216   -10.68902 1.000 8.00299  ? 40  ALA F N   1 
ATOM   2416 C CA  . ALA D  1 42 ? -20.38109 0.05357   -10.66640 1.000 8.87019  ? 40  ALA F CA  1 
ATOM   2417 C C   . ALA D  1 42 ? -20.15760 -0.86341  -9.46595  1.000 9.10896  ? 40  ALA F C   1 
ATOM   2418 O O   . ALA D  1 42 ? -19.22487 -1.67608  -9.50648  1.000 10.32598 ? 40  ALA F O   1 
ATOM   2419 C CB  . ALA D  1 42 ? -19.27395 1.10456   -10.70451 1.000 9.89690  ? 40  ALA F CB  1 
ATOM   2420 N N   . PHE D  1 43 ? -20.94940 -0.75808  -8.39805  1.000 8.43823  ? 41  PHE F N   1 
ATOM   2421 C CA  . PHE D  1 43 ? -20.66430 -1.55543  -7.21083  1.000 7.50153  ? 41  PHE F CA  1 
ATOM   2422 C C   . PHE D  1 43 ? -20.88455 -3.03772  -7.49456  1.000 8.08397  ? 41  PHE F C   1 
ATOM   2423 O O   . PHE D  1 43 ? -21.95606 -3.44062  -7.95714  1.000 9.77083  ? 41  PHE F O   1 
ATOM   2424 C CB  . PHE D  1 43 ? -21.55090 -1.13320  -6.04031  1.000 8.55384  ? 41  PHE F CB  1 
ATOM   2425 C CG  . PHE D  1 43 ? -21.23821 -1.86740  -4.77349  1.000 7.91900  ? 41  PHE F CG  1 
ATOM   2426 C CD1 . PHE D  1 43 ? -21.81006 -3.09569  -4.50287  1.000 9.10534  ? 41  PHE F CD1 1 
ATOM   2427 C CD2 . PHE D  1 43 ? -20.33815 -1.34577  -3.87125  1.000 11.43638 ? 41  PHE F CD2 1 
ATOM   2428 C CE1 . PHE D  1 43 ? -21.48966 -3.78561  -3.34535  1.000 10.09046 ? 41  PHE F CE1 1 
ATOM   2429 C CE2 . PHE D  1 43 ? -20.01413 -2.03462  -2.71378  1.000 11.28676 ? 41  PHE F CE2 1 
ATOM   2430 C CZ  . PHE D  1 43 ? -20.59558 -3.25301  -2.45684  1.000 10.34162 ? 41  PHE F CZ  1 
ATOM   2431 N N   . ASN D  1 44 ? -19.88839 -3.85956  -7.16712  1.000 9.14489  ? 42  ASN F N   1 
ATOM   2432 C CA  . ASN D  1 44 ? -20.02602 -5.30508  -7.32784  1.000 9.66783  ? 42  ASN F CA  1 
ATOM   2433 C C   . ASN D  1 44 ? -19.03174 -5.94905  -6.36978  1.000 10.60627 ? 42  ASN F C   1 
ATOM   2434 O O   . ASN D  1 44 ? -17.82664 -5.90181  -6.62272  1.000 12.14701 ? 42  ASN F O   1 
ATOM   2435 C CB  . ASN D  1 44 ? -19.72994 -5.68950  -8.77811  1.000 13.86849 ? 42  ASN F CB  1 
ATOM   2436 C CG  . ASN D  1 44 ? -20.09627 -7.12485  -9.09329  1.000 16.34282 ? 42  ASN F CG  1 
ATOM   2437 O OD1 . ASN D  1 44 ? -19.71164 -8.04740  -8.37937  1.000 21.80667 ? 42  ASN F OD1 1 
ATOM   2438 N ND2 . ASN D  1 44 ? -20.86388 -7.31775  -10.16024 1.000 22.55964 ? 42  ASN F ND2 1 
ATOM   2439 N N   . GLU D  1 45 ? -19.51946 -6.53453  -5.27878  1.000 9.09279  ? 43  GLU F N   1 
ATOM   2440 C CA  . GLU D  1 45 ? -18.65398 -7.12703  -4.26601  1.000 9.80047  ? 43  GLU F CA  1 
ATOM   2441 C C   . GLU D  1 45 ? -19.35018 -8.33429  -3.66936  1.000 9.16378  ? 43  GLU F C   1 
ATOM   2442 O O   . GLU D  1 45 ? -20.58404 -8.40098  -3.65769  1.000 10.04933 ? 43  GLU F O   1 
ATOM   2443 C CB  . GLU D  1 45 ? -18.34784 -6.14062  -3.13026  1.000 12.13932 ? 43  GLU F CB  1 
ATOM   2444 C CG  . GLU D  1 45 ? -17.66605 -4.85711  -3.54347  1.000 12.31093 ? 43  GLU F CG  1 
ATOM   2445 C CD  . GLU D  1 45 ? -16.28303 -5.07408  -4.11107  1.000 14.07853 ? 43  GLU F CD  1 
ATOM   2446 O OE1 . GLU D  1 45 ? -15.73170 -6.18897  -3.97637  1.000 14.58754 ? 43  GLU F OE1 1 
ATOM   2447 O OE2 . GLU D  1 45 ? -15.73948 -4.11559  -4.69939  1.000 15.46466 ? 43  GLU F OE2 1 
ATOM   2448 N N   . PRO D  1 46 ? -18.59329 -9.28107  -3.11473  1.000 9.59108  ? 44  PRO F N   1 
ATOM   2449 C CA  . PRO D  1 46 ? -19.22372 -10.41738 -2.43733  1.000 9.30947  ? 44  PRO F CA  1 
ATOM   2450 C C   . PRO D  1 46 ? -19.90794 -9.99773  -1.14539  1.000 9.44466  ? 44  PRO F C   1 
ATOM   2451 O O   . PRO D  1 46 ? -19.46559 -9.08840  -0.43462  1.000 10.91882 ? 44  PRO F O   1 
ATOM   2452 C CB  . PRO D  1 46 ? -18.04935 -11.35675 -2.13465  1.000 12.32523 ? 44  PRO F CB  1 
ATOM   2453 C CG  . PRO D  1 46 ? -16.90392 -10.85503 -2.92933  1.000 17.02030 ? 44  PRO F CG  1 
ATOM   2454 C CD  . PRO D  1 46 ? -17.12773 -9.40454  -3.17084  1.000 10.26772 ? 44  PRO F CD  1 
ATOM   2455 N N   . GLY D  1 47 ? -20.99249 -10.70380 -0.83710  1.000 9.86992  ? 45  GLY F N   1 
ATOM   2456 C CA  . GLY D  1 47 ? -21.68858 -10.51620 0.41645   1.000 10.59621 ? 45  GLY F CA  1 
ATOM   2457 C C   . GLY D  1 47 ? -23.01818 -11.23603 0.44293   1.000 9.90192  ? 45  GLY F C   1 
ATOM   2458 O O   . GLY D  1 47 ? -23.73952 -11.26576 -0.56068  1.000 10.74741 ? 45  GLY F O   1 
ATOM   2459 N N   . ASP D  1 48 ? -23.34381 -11.83112 1.58968   1.000 10.25693 ? 46  ASP F N   1 
ATOM   2460 C CA  . ASP D  1 48 ? -24.66487 -12.38798 1.84757   1.000 10.24381 ? 46  ASP F CA  1 
ATOM   2461 C C   . ASP D  1 48 ? -25.60224 -11.37078 2.45611   1.000 10.60227 ? 46  ASP F C   1 
ATOM   2462 O O   . ASP D  1 48 ? -26.82676 -11.53044 2.36847   1.000 14.45610 ? 46  ASP F O   1 
ATOM   2463 C CB  . ASP D  1 48 ? -24.56427 -13.49108 2.90136   1.000 19.02756 ? 46  ASP F CB  1 
ATOM   2464 C CG  . ASP D  1 48 ? -24.06982 -14.78865 2.34183   1.000 22.80048 ? 46  ASP F CG  1 
ATOM   2465 O OD1 . ASP D  1 48 ? -24.30995 -15.04570 1.14535   1.000 28.02882 ? 46  ASP F OD1 1 
ATOM   2466 O OD2 . ASP D  1 48 ? -23.45060 -15.55497 3.10923   1.000 19.85906 ? 46  ASP F OD2 1 
ATOM   2467 N N   . ASN D  1 49 ? -25.05143 -10.36275 3.11766   1.000 9.05240  ? 47  ASN F N   1 
ATOM   2468 C CA  . ASN D  1 49 ? -25.82578 -9.35821  3.81881   1.000 9.52896  ? 47  ASN F CA  1 
ATOM   2469 C C   . ASN D  1 49 ? -25.24455 -8.00067  3.47952   1.000 8.21303  ? 47  ASN F C   1 
ATOM   2470 O O   . ASN D  1 49 ? -24.02944 -7.86637  3.31479   1.000 8.76222  ? 47  ASN F O   1 
ATOM   2471 C CB  . ASN D  1 49 ? -25.75178 -9.58596  5.32899   1.000 11.58817 ? 47  ASN F CB  1 
ATOM   2472 C CG  . ASN D  1 49 ? -26.43726 -8.49379  6.11020   1.000 11.24722 ? 47  ASN F CG  1 
ATOM   2473 O OD1 . ASN D  1 49 ? -25.79539 -7.54674  6.57702   1.000 11.93026 ? 47  ASN F OD1 1 
ATOM   2474 N ND2 . ASN D  1 49 ? -27.75325 -8.60231  6.23944   1.000 14.32621 ? 47  ASN F ND2 1 
ATOM   2475 N N   . VAL D  1 50 ? -26.11161 -6.99934  3.37022   1.000 8.22639  ? 48  VAL F N   1 
ATOM   2476 C CA  . VAL D  1 50 ? -25.68336 -5.66840  2.97317   1.000 7.72648  ? 48  VAL F CA  1 
ATOM   2477 C C   . VAL D  1 50 ? -26.44465 -4.62092  3.76953   1.000 6.63839  ? 48  VAL F C   1 
ATOM   2478 O O   . VAL D  1 50 ? -27.65370 -4.74499  4.00275   1.000 8.48719  ? 48  VAL F O   1 
ATOM   2479 C CB  . VAL D  1 50 ? -25.84201 -5.45837  1.44780   1.000 9.55276  ? 48  VAL F CB  1 
ATOM   2480 C CG1 . VAL D  1 50 ? -27.30245 -5.63313  1.00077   1.000 11.00810 ? 48  VAL F CG1 1 
ATOM   2481 C CG2 . VAL D  1 50 ? -25.30597 -4.10695  1.02879   1.000 10.59994 ? 48  VAL F CG2 1 
ATOM   2482 N N   . SER D  1 51 ? -25.72263 -3.58997  4.18742   1.000 7.12068  ? 49  SER F N   1 
ATOM   2483 C CA  . SER D  1 51 ? -26.33601 -2.36306  4.66137   1.000 6.51861  ? 49  SER F CA  1 
ATOM   2484 C C   . SER D  1 51 ? -25.60322 -1.19788  4.01495   1.000 5.67760  ? 49  SER F C   1 
ATOM   2485 O O   . SER D  1 51 ? -24.50675 -1.36016  3.47911   1.000 7.13098  ? 49  SER F O   1 
ATOM   2486 C CB  . SER D  1 51 ? -26.31910 -2.24284  6.19550   1.000 7.37717  ? 49  SER F CB  1 
ATOM   2487 O OG  . SER D  1 51 ? -25.00327 -2.09719  6.70297   1.000 8.05554  ? 49  SER F OG  1 
ATOM   2488 N N   . VAL D  1 52 ? -26.21918 -0.01698  4.05819   1.000 6.16963  ? 50  VAL F N   1 
ATOM   2489 C CA  . VAL D  1 52 ? -25.65286 1.15464   3.40450   1.000 6.02234  ? 50  VAL F CA  1 
ATOM   2490 C C   . VAL D  1 52 ? -26.02882 2.39904   4.18502   1.000 6.26466  ? 50  VAL F C   1 
ATOM   2491 O O   . VAL D  1 52 ? -27.09413 2.47289   4.80333   1.000 7.69154  ? 50  VAL F O   1 
ATOM   2492 C CB  . VAL D  1 52 ? -26.13978 1.26745   1.93707   1.000 6.99881  ? 50  VAL F CB  1 
ATOM   2493 C CG1 . VAL D  1 52 ? -27.65107 1.47504   1.85663   1.000 7.86997  ? 50  VAL F CG1 1 
ATOM   2494 C CG2 . VAL D  1 52 ? -25.39195 2.36775   1.18992   1.000 8.24684  ? 50  VAL F CG2 1 
ATOM   2495 N N   . THR D  1 53 ? -25.14778 3.39066   4.12551   1.000 6.12334  ? 51  THR F N   1 
ATOM   2496 C CA  . THR D  1 53 ? -25.47124 4.74353   4.53203   1.000 6.89906  ? 51  THR F CA  1 
ATOM   2497 C C   . THR D  1 53 ? -24.75509 5.68369   3.57663   1.000 6.83348  ? 51  THR F C   1 
ATOM   2498 O O   . THR D  1 53 ? -23.79468 5.29749   2.90705   1.000 8.20954  ? 51  THR F O   1 
ATOM   2499 C CB  . THR D  1 53 ? -25.10001 4.99627   6.01033   1.000 7.03555  ? 51  THR F CB  1 
ATOM   2500 O OG1 . THR D  1 53 ? -25.61014 6.26438   6.42830   1.000 8.01773  ? 51  THR F OG1 1 
ATOM   2501 C CG2 . THR D  1 53 ? -23.59375 4.98179   6.22996   1.000 8.87108  ? 51  THR F CG2 1 
ATOM   2502 N N   . SER D  1 54 ? -25.23728 6.92134   3.49700   1.000 7.14182  ? 52  SER F N   1 
ATOM   2503 C CA  . SER D  1 54 ? -24.59611 7.90718   2.64470   1.000 7.68199  ? 52  SER F CA  1 
ATOM   2504 C C   . SER D  1 54 ? -24.80129 9.28803   3.24740   1.000 7.98236  ? 52  SER F C   1 
ATOM   2505 O O   . SER D  1 54 ? -25.72808 9.51380   4.02810   1.000 8.11349  ? 52  SER F O   1 
ATOM   2506 C CB  . SER D  1 54 ? -25.12400 7.85096   1.20227   1.000 8.11304  ? 52  SER F CB  1 
ATOM   2507 O OG  . SER D  1 54 ? -26.47812 8.26968   1.12140   1.000 8.16511  ? 52  SER F OG  1 
ATOM   2508 N N   . TRP D  1 55 ? -23.92441 10.21796  2.87221   1.000 8.34494  ? 53  TRP F N   1 
ATOM   2509 C CA  . TRP D  1 55 ? -24.02076 11.60010  3.32485   1.000 9.08582  ? 53  TRP F CA  1 
ATOM   2510 C C   . TRP D  1 55 ? -23.49355 12.50684  2.22478   1.000 9.54563  ? 53  TRP F C   1 
ATOM   2511 O O   . TRP D  1 55 ? -22.62485 12.11861  1.44072   1.000 9.69745  ? 53  TRP F O   1 
ATOM   2512 C CB  . TRP D  1 55 ? -23.25318 11.86341  4.63949   1.000 10.26356 ? 53  TRP F CB  1 
ATOM   2513 C CG  . TRP D  1 55 ? -21.76281 11.67970  4.51202   1.000 8.87907  ? 53  TRP F CG  1 
ATOM   2514 C CD1 . TRP D  1 55 ? -20.82331 12.64429  4.25216   1.000 10.83627 ? 53  TRP F CD1 1 
ATOM   2515 C CD2 . TRP D  1 55 ? -21.04882 10.44935  4.62027   1.000 8.57083  ? 53  TRP F CD2 1 
ATOM   2516 N NE1 . TRP D  1 55 ? -19.57091 12.08106  4.19062   1.000 9.89508  ? 53  TRP F NE1 1 
ATOM   2517 C CE2 . TRP D  1 55 ? -19.68211 10.73434  4.41570   1.000 9.57636  ? 53  TRP F CE2 1 
ATOM   2518 C CE3 . TRP D  1 55 ? -21.43199 9.12991   4.87700   1.000 9.35481  ? 53  TRP F CE3 1 
ATOM   2519 C CZ2 . TRP D  1 55 ? -18.70348 9.74234   4.44454   1.000 9.65393  ? 53  TRP F CZ2 1 
ATOM   2520 C CZ3 . TRP D  1 55 ? -20.46619 8.15602   4.91573   1.000 8.62701  ? 53  TRP F CZ3 1 
ATOM   2521 C CH2 . TRP D  1 55 ? -19.11627 8.46518   4.70226   1.000 8.86148  ? 53  TRP F CH2 1 
ATOM   2522 N N   . LEU D  1 56 ? -24.02632 13.72226  2.17821   1.000 9.95018  ? 54  LEU F N   1 
ATOM   2523 C CA  . LEU D  1 56 ? -23.55805 14.74605  1.25740   1.000 9.63249  ? 54  LEU F CA  1 
ATOM   2524 C C   . LEU D  1 56 ? -22.56783 15.66374  1.95538   1.000 11.73082 ? 54  LEU F C   1 
ATOM   2525 O O   . LEU D  1 56 ? -22.72261 15.98566  3.13551   1.000 11.72129 ? 54  LEU F O   1 
ATOM   2526 C CB  . LEU D  1 56 ? -24.72593 15.59520  0.75630   1.000 10.36362 ? 54  LEU F CB  1 
ATOM   2527 C CG  . LEU D  1 56 ? -25.65752 14.92119  -0.23942  1.000 11.13935 ? 54  LEU F CG  1 
ATOM   2528 C CD1 . LEU D  1 56 ? -26.93091 15.73669  -0.37495  1.000 12.59055 ? 54  LEU F CD1 1 
ATOM   2529 C CD2 . LEU D  1 56 ? -24.97108 14.78476  -1.58326  1.000 13.61749 ? 54  LEU F CD2 1 
ATOM   2530 N N   . VAL D  1 57 ? -21.55696 16.08816  1.21599   1.000 10.98755 ? 55  VAL F N   1 
ATOM   2531 C CA  . VAL D  1 57 ? -20.74499 17.23647  1.59014   1.000 11.67177 ? 55  VAL F CA  1 
ATOM   2532 C C   . VAL D  1 57 ? -20.94923 18.22793  0.45558   1.000 11.97068 ? 55  VAL F C   1 
ATOM   2533 O O   . VAL D  1 57 ? -20.36581 18.08030  -0.62048  1.000 12.99125 ? 55  VAL F O   1 
ATOM   2534 C CB  . VAL D  1 57 ? -19.26876 16.87889  1.78474   1.000 11.58150 ? 55  VAL F CB  1 
ATOM   2535 C CG1 . VAL D  1 57 ? -18.49262 18.11158  2.19734   1.000 13.56941 ? 55  VAL F CG1 1 
ATOM   2536 C CG2 . VAL D  1 57 ? -19.11625 15.77469  2.82652   1.000 13.41250 ? 55  VAL F CG2 1 
ATOM   2537 N N   . GLY D  1 58 ? -21.82171 19.20354  0.66901   1.000 13.51312 ? 56  GLY F N   1 
ATOM   2538 C CA  . GLY D  1 58 ? -22.25023 20.03978  -0.44276  1.000 14.01658 ? 56  GLY F CA  1 
ATOM   2539 C C   . GLY D  1 58 ? -22.97273 19.20297  -1.48308  1.000 13.35600 ? 56  GLY F C   1 
ATOM   2540 O O   . GLY D  1 58 ? -23.97102 18.53503  -1.18748  1.000 14.95862 ? 56  GLY F O   1 
ATOM   2541 N N   . SER D  1 59 ? -22.46755 19.22241  -2.71309  1.000 14.02725 ? 57  SER F N   1 
ATOM   2542 C CA  . SER D  1 59 ? -23.03314 18.42458  -3.79116  1.000 13.94440 ? 57  SER F CA  1 
ATOM   2543 C C   . SER D  1 59 ? -22.42528 17.03174  -3.89885  1.000 12.83263 ? 57  SER F C   1 
ATOM   2544 O O   . SER D  1 59 ? -22.93256 16.21512  -4.67649  1.000 16.40163 ? 57  SER F O   1 
ATOM   2545 C CB  . SER D  1 59 ? -22.85552 19.14863  -5.13052  1.000 15.67195 ? 57  SER F CB  1 
ATOM   2546 O OG  . SER D  1 59 ? -21.49007 19.21043  -5.50115  1.000 19.40264 ? 57  SER F OG  1 
ATOM   2547 N N   . ALA D  1 60 ? -21.36528 16.73597  -3.14918  1.000 12.93651 ? 58  ALA F N   1 
ATOM   2548 C CA  . ALA D  1 60 ? -20.62082 15.49280  -3.31167  1.000 14.77820 ? 58  ALA F CA  1 
ATOM   2549 C C   . ALA D  1 60 ? -21.21063 14.40778  -2.41777  1.000 10.49895 ? 58  ALA F C   1 
ATOM   2550 O O   . ALA D  1 60 ? -21.29096 14.57584  -1.19867  1.000 11.60283 ? 58  ALA F O   1 
ATOM   2551 C CB  . ALA D  1 60 ? -19.15185 15.71886  -2.96512  1.000 15.41910 ? 58  ALA F CB  1 
ATOM   2552 N N   . ILE D  1 61 ? -21.60467 13.29205  -3.02051  1.000 11.45565 ? 59  ILE F N   1 
ATOM   2553 C CA  . ILE D  1 61 ? -22.12832 12.15193  -2.27710  1.000 9.53291  ? 59  ILE F CA  1 
ATOM   2554 C C   . ILE D  1 61 ? -20.98471 11.24942  -1.83235  1.000 9.20907  ? 59  ILE F C   1 
ATOM   2555 O O   . ILE D  1 61 ? -20.00454 11.03168  -2.55404  1.000 10.96577 ? 59  ILE F O   1 
ATOM   2556 C CB  . ILE D  1 61 ? -23.18365 11.38031  -3.09790  1.000 9.47257  ? 59  ILE F CB  1 
ATOM   2557 C CG1 . ILE D  1 61 ? -23.91540 10.35330  -2.22813  1.000 10.34579 ? 59  ILE F CG1 1 
ATOM   2558 C CG2 . ILE D  1 61 ? -22.55201 10.69688  -4.30456  1.000 12.75421 ? 59  ILE F CG2 1 
ATOM   2559 C CD1 . ILE D  1 61 ? -24.70477 10.96891  -1.08092  1.000 11.06736 ? 59  ILE F CD1 1 
ATOM   2560 N N   . HIS D  1 62 ? -21.12437 10.71580  -0.62598  1.000 8.59415  ? 60  HIS F N   1 
ATOM   2561 C CA  . HIS D  1 62 ? -20.22123 9.71858   -0.07924  1.000 8.20883  ? 60  HIS F CA  1 
ATOM   2562 C C   . HIS D  1 62 ? -21.08271 8.55412   0.37378   1.000 7.05350  ? 60  HIS F C   1 
ATOM   2563 O O   . HIS D  1 62 ? -22.03730 8.75100   1.12758   1.000 8.70273  ? 60  HIS F O   1 
ATOM   2564 C CB  . HIS D  1 62 ? -19.45678 10.32180  1.09096   1.000 9.53462  ? 60  HIS F CB  1 
ATOM   2565 C CG  . HIS D  1 62 ? -18.62497 11.50146  0.69658   1.000 9.02279  ? 60  HIS F CG  1 
ATOM   2566 N ND1 . HIS D  1 62 ? -17.30458 11.38271  0.32212   1.000 10.92162 ? 60  HIS F ND1 1 
ATOM   2567 C CD2 . HIS D  1 62 ? -18.93825 12.81221  0.56276   1.000 10.81232 ? 60  HIS F CD2 1 
ATOM   2568 C CE1 . HIS D  1 62 ? -16.83310 12.57402  -0.00345  1.000 12.20352 ? 60  HIS F CE1 1 
ATOM   2569 N NE2 . HIS D  1 62 ? -17.80451 13.45823  0.13528   1.000 13.54228 ? 60  HIS F NE2 1 
ATOM   2570 N N   . ILE D  1 63 ? -20.77242 7.35623   -0.10425  1.000 7.32022  ? 61  ILE F N   1 
ATOM   2571 C CA  . ILE D  1 63 ? -21.56249 6.16559   0.17854   1.000 6.99709  ? 61  ILE F CA  1 
ATOM   2572 C C   . ILE D  1 63 ? -20.67717 5.16494   0.90196   1.000 6.67867  ? 61  ILE F C   1 
ATOM   2573 O O   . ILE D  1 63 ? -19.50649 5.00139   0.54504   1.000 6.85191  ? 61  ILE F O   1 
ATOM   2574 C CB  . ILE D  1 63 ? -22.14096 5.52364   -1.10272  1.000 7.13120  ? 61  ILE F CB  1 
ATOM   2575 C CG1 . ILE D  1 63 ? -22.75934 6.58006   -2.02765  1.000 7.68832  ? 61  ILE F CG1 1 
ATOM   2576 C CG2 . ILE D  1 63 ? -23.14944 4.42711   -0.75313  1.000 7.80123  ? 61  ILE F CG2 1 
ATOM   2577 C CD1 . ILE D  1 63 ? -23.13538 6.04569   -3.40251  1.000 9.12600  ? 61  ILE F CD1 1 
ATOM   2578 N N   . ARG D  1 64 ? -21.23133 4.50086   1.91443   1.000 6.38954  ? 62  ARG F N   1 
ATOM   2579 C CA  . ARG D  1 64 ? -20.55051 3.40038   2.58884   1.000 6.33504  ? 62  ARG F CA  1 
ATOM   2580 C C   . ARG D  1 64 ? -21.45807 2.18401   2.57190   1.000 6.42588  ? 62  ARG F C   1 
ATOM   2581 O O   . ARG D  1 64 ? -22.58567 2.24323   3.06808   1.000 7.18412  ? 62  ARG F O   1 
ATOM   2582 C CB  . ARG D  1 64 ? -20.18330 3.76946   4.02696   1.000 7.01876  ? 62  ARG F CB  1 
ATOM   2583 C CG  . ARG D  1 64 ? -19.21399 4.93375   4.12924   1.000 7.14865  ? 62  ARG F CG  1 
ATOM   2584 C CD  . ARG D  1 64 ? -17.83704 4.61028   3.54949   1.000 7.41502  ? 62  ARG F CD  1 
ATOM   2585 N NE  . ARG D  1 64 ? -16.90019 5.72475   3.66670   1.000 7.74116  ? 62  ARG F NE  1 
ATOM   2586 C CZ  . ARG D  1 64 ? -16.77193 6.69728   2.76996   1.000 8.12503  ? 62  ARG F CZ  1 
ATOM   2587 N NH1 . ARG D  1 64 ? -17.49696 6.72136   1.65825   1.000 7.65775  ? 62  ARG F NH1 1 
ATOM   2588 N NH2 . ARG D  1 64 ? -15.89968 7.68115   2.99723   1.000 8.40694  ? 62  ARG F NH2 1 
ATOM   2589 N N   . VAL D  1 65 ? -20.97365 1.09660   1.98410   1.000 6.73227  ? 63  VAL F N   1 
ATOM   2590 C CA  . VAL D  1 65 ? -21.69481 -0.16454  1.90293   1.000 6.68347  ? 63  VAL F CA  1 
ATOM   2591 C C   . VAL D  1 65 ? -20.96782 -1.17055  2.78210   1.000 6.41573  ? 63  VAL F C   1 
ATOM   2592 O O   . VAL D  1 65 ? -19.74706 -1.32664  2.66746   1.000 7.42117  ? 63  VAL F O   1 
ATOM   2593 C CB  . VAL D  1 65 ? -21.76744 -0.66564  0.44901   1.000 7.49262  ? 63  VAL F CB  1 
ATOM   2594 C CG1 . VAL D  1 65 ? -22.41499 -2.03219  0.39790   1.000 9.93194  ? 63  VAL F CG1 1 
ATOM   2595 C CG2 . VAL D  1 65 ? -22.54151 0.31431   -0.41195  1.000 8.24006  ? 63  VAL F CG2 1 
ATOM   2596 N N   . TYR D  1 66 ? -21.70548 -1.82678  3.67721   1.000 6.58995  ? 64  TYR F N   1 
ATOM   2597 C CA  . TYR D  1 66 ? -21.15482 -2.81659  4.60069   1.000 6.84243  ? 64  TYR F CA  1 
ATOM   2598 C C   . TYR D  1 66 ? -21.60518 -4.18819  4.11909   1.000 6.42356  ? 64  TYR F C   1 
ATOM   2599 O O   . TYR D  1 66 ? -22.79147 -4.51757  4.18132   1.000 7.29550  ? 64  TYR F O   1 
ATOM   2600 C CB  . TYR D  1 66 ? -21.57040 -2.50623  6.04971   1.000 6.63527  ? 64  TYR F CB  1 
ATOM   2601 C CG  . TYR D  1 66 ? -21.02287 -1.15407  6.43692   1.000 6.19286  ? 64  TYR F CG  1 
ATOM   2602 C CD1 . TYR D  1 66 ? -19.73156 -1.01522  6.91603   1.000 7.06863  ? 64  TYR F CD1 1 
ATOM   2603 C CD2 . TYR D  1 66 ? -21.76445 -0.00648  6.22213   1.000 6.73243  ? 64  TYR F CD2 1 
ATOM   2604 C CE1 . TYR D  1 66 ? -19.20830 0.23289   7.18983   1.000 7.16086  ? 64  TYR F CE1 1 
ATOM   2605 C CE2 . TYR D  1 66 ? -21.25895 1.23615   6.48269   1.000 6.22396  ? 64  TYR F CE2 1 
ATOM   2606 C CZ  . TYR D  1 66 ? -19.97515 1.35863   6.95491   1.000 5.46443  ? 64  TYR F CZ  1 
ATOM   2607 O OH  . TYR D  1 66 ? -19.46328 2.61785   7.18724   1.000 6.77046  ? 64  TYR F OH  1 
ATOM   2608 N N   . ALA D  1 67 ? -20.66480 -4.95829  3.58485   1.000 7.23498  ? 65  ALA F N   1 
ATOM   2609 C CA  . ALA D  1 67 ? -20.93652 -6.25127  2.97892   1.000 7.48224  ? 65  ALA F CA  1 
ATOM   2610 C C   . ALA D  1 67 ? -20.41436 -7.33600  3.90719   1.000 7.89108  ? 65  ALA F C   1 
ATOM   2611 O O   . ALA D  1 67 ? -19.23722 -7.31485  4.28329   1.000 9.33957  ? 65  ALA F O   1 
ATOM   2612 C CB  . ALA D  1 67 ? -20.21439 -6.34405  1.63720   1.000 9.02196  ? 65  ALA F CB  1 
ATOM   2613 N N   . SER D  1 68 ? -21.27111 -8.28432  4.27076   1.000 7.26310  ? 66  SER F N   1 
ATOM   2614 C CA  . SER D  1 68 ? -20.89979 -9.31369  5.23337   1.000 8.26649  ? 66  SER F CA  1 
ATOM   2615 C C   . SER D  1 68 ? -20.99518 -10.69502 4.61388   1.000 9.09577  ? 66  SER F C   1 
ATOM   2616 O O   . SER D  1 68 ? -21.98484 -11.02078 3.95106   1.000 10.03955 ? 66  SER F O   1 
ATOM   2617 C CB  . SER D  1 68 ? -21.75942 -9.25732  6.49258   1.000 9.72666  ? 66  SER F CB  1 
ATOM   2618 O OG  . SER D  1 68 ? -21.57482 -8.02080  7.16484   1.000 10.32844 ? 66  SER F OG  1 
ATOM   2619 N N   . THR D  1 69 ? -19.97297 -11.50630 4.86441   1.000 9.89422  ? 67  THR F N   1 
ATOM   2620 C CA  . THR D  1 69 ? -19.98251 -12.92702 4.54362   1.000 10.97638 ? 67  THR F CA  1 
ATOM   2621 C C   . THR D  1 69 ? -19.45451 -13.63607 5.77823   1.000 11.03592 ? 67  THR F C   1 
ATOM   2622 O O   . THR D  1 69 ? -18.34997 -13.32892 6.24178   1.000 12.17922 ? 67  THR F O   1 
ATOM   2623 C CB  . THR D  1 69 ? -19.09219 -13.22583 3.33070   1.000 13.23905 ? 67  THR F CB  1 
ATOM   2624 O OG1 . THR D  1 69 ? -19.56762 -12.50163 2.18805   1.000 14.97420 ? 67  THR F OG1 1 
ATOM   2625 C CG2 . THR D  1 69 ? -19.10726 -14.71459 3.01718   1.000 16.46917 ? 67  THR F CG2 1 
ATOM   2626 N N   . GLY D  1 70 ? -20.25475 -14.53749 6.33867   1.000 11.48964 ? 68  GLY F N   1 
ATOM   2627 C CA  . GLY D  1 70 ? -19.86557 -15.14761 7.59741   1.000 13.13028 ? 68  GLY F CA  1 
ATOM   2628 C C   . GLY D  1 70 ? -19.82320 -14.09023 8.68227   1.000 11.35122 ? 68  GLY F C   1 
ATOM   2629 O O   . GLY D  1 70 ? -20.74222 -13.27428 8.82389   1.000 13.38662 ? 68  GLY F O   1 
ATOM   2630 N N   . THR D  1 71 ? -18.73623 -14.06301 9.44455   1.000 13.31984 ? 69  THR F N   1 
ATOM   2631 C CA  . THR D  1 71 ? -18.56300 -13.05193 10.47614  1.000 14.69909 ? 69  THR F CA  1 
ATOM   2632 C C   . THR D  1 71 ? -17.71017 -11.87144 10.02259  1.000 14.35700 ? 69  THR F C   1 
ATOM   2633 O O   . THR D  1 71 ? -17.37711 -11.01516 10.84404  1.000 16.01744 ? 69  THR F O   1 
ATOM   2634 C CB  . THR D  1 71 ? -17.97640 -13.67483 11.74403  1.000 20.49652 ? 69  THR F CB  1 
ATOM   2635 O OG1 . THR D  1 71 ? -16.72105 -14.28804 11.43347  1.000 21.92667 ? 69  THR F OG1 1 
ATOM   2636 C CG2 . THR D  1 71 ? -18.92115 -14.72340 12.30773  1.000 22.73437 ? 69  THR F CG2 1 
ATOM   2637 N N   . THR D  1 72 ? -17.36227 -11.78861 8.74282   1.000 11.38650 ? 70  THR F N   1 
ATOM   2638 C CA  . THR D  1 72 ? -16.47963 -10.73835 8.25146   1.000 10.86769 ? 70  THR F CA  1 
ATOM   2639 C C   . THR D  1 72 ? -17.28062 -9.68809  7.49373   1.000 10.01201 ? 70  THR F C   1 
ATOM   2640 O O   . THR D  1 72 ? -17.90838 -9.99623  6.47300   1.000 10.64997 ? 70  THR F O   1 
ATOM   2641 C CB  . THR D  1 72 ? -15.39850 -11.32663 7.35236   1.000 13.07299 ? 70  THR F CB  1 
ATOM   2642 O OG1 . THR D  1 72 ? -14.67919 -12.32858 8.08295   1.000 16.94483 ? 70  THR F OG1 1 
ATOM   2643 C CG2 . THR D  1 72 ? -14.43382 -10.24149 6.89896   1.000 15.57018 ? 70  THR F CG2 1 
ATOM   2644 N N   . THR D  1 73 ? -17.23318 -8.45219  7.97854   1.000 9.38518  ? 71  THR F N   1 
ATOM   2645 C CA  . THR D  1 73 ? -17.87365 -7.31667  7.33413   1.000 8.30766  ? 71  THR F CA  1 
ATOM   2646 C C   . THR D  1 73 ? -16.80071 -6.44212  6.70936   1.000 9.11428  ? 71  THR F C   1 
ATOM   2647 O O   . THR D  1 73 ? -15.86282 -6.01792  7.39326   1.000 9.90898  ? 71  THR F O   1 
ATOM   2648 C CB  . THR D  1 73 ? -18.65369 -6.49518  8.35834   1.000 9.78074  ? 71  THR F CB  1 
ATOM   2649 O OG1 . THR D  1 73 ? -19.64798 -7.31890  8.97532   1.000 10.56058 ? 71  THR F OG1 1 
ATOM   2650 C CG2 . THR D  1 73 ? -19.31703 -5.30139  7.69090   1.000 10.15931 ? 71  THR F CG2 1 
ATOM   2651 N N   . THR D  1 74 ? -16.94344 -6.17321  5.41877   1.000 7.94814  ? 72  THR F N   1 
ATOM   2652 C CA  . THR D  1 74 ? -16.03819 -5.30862  4.68123   1.000 7.19327  ? 72  THR F CA  1 
ATOM   2653 C C   . THR D  1 74 ? -16.78524 -4.03252  4.33113   1.000 6.91780  ? 72  THR F C   1 
ATOM   2654 O O   . THR D  1 74 ? -17.90458 -4.09163  3.81074   1.000 8.36683  ? 72  THR F O   1 
ATOM   2655 C CB  . THR D  1 74 ? -15.58968 -5.99417  3.38657   1.000 8.82772  ? 72  THR F CB  1 
ATOM   2656 O OG1 . THR D  1 74 ? -14.95481 -7.24391  3.68466   1.000 9.64805  ? 72  THR F OG1 1 
ATOM   2657 C CG2 . THR D  1 74 ? -14.61322 -5.11334  2.62630   1.000 9.65412  ? 72  THR F CG2 1 
ATOM   2658 N N   . GLU D  1 75 ? -16.16792 -2.88967  4.60684   1.000 7.30653  ? 73  GLU F N   1 
ATOM   2659 C CA  . GLU D  1 75 ? -16.71065 -1.59636  4.21921   1.000 6.74439  ? 73  GLU F CA  1 
ATOM   2660 C C   . GLU D  1 75 ? -16.17674 -1.20264  2.85430   1.000 6.80184  ? 73  GLU F C   1 
ATOM   2661 O O   . GLU D  1 75 ? -14.96704 -1.27039  2.61213   1.000 7.73938  ? 73  GLU F O   1 
ATOM   2662 C CB  . GLU D  1 75 ? -16.28142 -0.54645  5.23152   1.000 6.43573  ? 73  GLU F CB  1 
ATOM   2663 C CG  . GLU D  1 75 ? -16.72374 0.86238   4.93550   1.000 6.74353  ? 73  GLU F CG  1 
ATOM   2664 C CD  . GLU D  1 75 ? -16.10975 1.86648   5.88672   1.000 6.87525  ? 73  GLU F CD  1 
ATOM   2665 O OE1 . GLU D  1 75 ? -14.88098 1.80451   6.10000   1.000 7.25077  ? 73  GLU F OE1 1 
ATOM   2666 O OE2 . GLU D  1 75 ? -16.85396 2.72250   6.41963   1.000 6.89439  ? 73  GLU F OE2 1 
ATOM   2667 N N   . TRP D  1 76 ? -17.07888 -0.76819  1.98078   1.000 6.75966  ? 74  TRP F N   1 
ATOM   2668 C CA  . TRP D  1 76 ? -16.73358 -0.25737  0.66682   1.000 7.21603  ? 74  TRP F CA  1 
ATOM   2669 C C   . TRP D  1 76 ? -17.16654 1.19826   0.58003   1.000 6.82179  ? 74  TRP F C   1 
ATOM   2670 O O   . TRP D  1 76 ? -18.26244 1.55745   1.02837   1.000 7.63557  ? 74  TRP F O   1 
ATOM   2671 C CB  . TRP D  1 76 ? -17.41950 -1.09358  -0.41715  1.000 7.48254  ? 74  TRP F CB  1 
ATOM   2672 C CG  . TRP D  1 76 ? -16.90596 -2.48963  -0.44981  1.000 8.87258  ? 74  TRP F CG  1 
ATOM   2673 C CD1 . TRP D  1 76 ? -17.49254 -3.60251  0.08505   1.000 8.65607  ? 74  TRP F CD1 1 
ATOM   2674 C CD2 . TRP D  1 76 ? -15.66610 -2.92050  -1.01210  1.000 8.40819  ? 74  TRP F CD2 1 
ATOM   2675 N NE1 . TRP D  1 76 ? -16.70070 -4.70655  -0.13159  1.000 9.29440  ? 74  TRP F NE1 1 
ATOM   2676 C CE2 . TRP D  1 76 ? -15.56832 -4.30997  -0.79529  1.000 9.94577  ? 74  TRP F CE2 1 
ATOM   2677 C CE3 . TRP D  1 76 ? -14.62765 -2.26434  -1.67637  1.000 10.35188 ? 74  TRP F CE3 1 
ATOM   2678 C CZ2 . TRP D  1 76 ? -14.47323 -5.05811  -1.23643  1.000 11.08039 ? 74  TRP F CZ2 1 
ATOM   2679 C CZ3 . TRP D  1 76 ? -13.54194 -3.00725  -2.10865  1.000 11.80713 ? 74  TRP F CZ3 1 
ATOM   2680 C CH2 . TRP D  1 76 ? -13.47466 -4.38937  -1.88504  1.000 13.09652 ? 74  TRP F CH2 1 
ATOM   2681 N N   . CYS D  1 77 ? -16.31123 2.03099   -0.00805  1.000 6.94655  ? 75  CYS F N   1 
ATOM   2682 C CA  . CYS D  1 77 ? -16.45072 3.47634   0.04322   1.000 7.58570  ? 75  CYS F CA  1 
ATOM   2683 C C   . CYS D  1 77 ? -16.53107 4.04804   -1.36043  1.000 7.06149  ? 75  CYS F C   1 
ATOM   2684 O O   . CYS D  1 77 ? -15.66739 3.76487   -2.19827  1.000 8.51602  ? 75  CYS F O   1 
ATOM   2685 C CB  . CYS D  1 77 ? -15.22905 4.08251   0.72343   1.000 7.57607  ? 75  CYS F CB  1 
ATOM   2686 S SG  . CYS D  1 77 ? -14.84747 3.37989   2.33285   1.000 8.48820  ? 75  CYS F SG  1 
ATOM   2687 N N   . TRP D  1 78 ? -17.54451 4.87203   -1.59883  1.000 7.41165  ? 76  TRP F N   1 
ATOM   2688 C CA  . TRP D  1 78 ? -17.62940 5.68888   -2.79942  1.000 9.57067  ? 76  TRP F CA  1 
ATOM   2689 C C   . TRP D  1 78 ? -17.43282 7.13071   -2.37555  1.000 9.41376  ? 76  TRP F C   1 
ATOM   2690 O O   . TRP D  1 78 ? -18.20902 7.65711   -1.57270  1.000 9.90356  ? 76  TRP F O   1 
ATOM   2691 C CB  . TRP D  1 78 ? -18.98099 5.55520   -3.49958  1.000 8.79936  ? 76  TRP F CB  1 
ATOM   2692 C CG  . TRP D  1 78 ? -19.04557 6.43525   -4.69544  1.000 10.27608 ? 76  TRP F CG  1 
ATOM   2693 C CD1 . TRP D  1 78 ? -19.50100 7.72597   -4.76276  1.000 11.89034 ? 76  TRP F CD1 1 
ATOM   2694 C CD2 . TRP D  1 78 ? -18.60620 6.09681   -6.00632  1.000 10.44829 ? 76  TRP F CD2 1 
ATOM   2695 N NE1 . TRP D  1 78 ? -19.37725 8.20295   -6.05231  1.000 12.05082 ? 76  TRP F NE1 1 
ATOM   2696 C CE2 . TRP D  1 78 ? -18.82656 7.22129   -6.83362  1.000 9.70195  ? 76  TRP F CE2 1 
ATOM   2697 C CE3 . TRP D  1 78 ? -18.05254 4.94837   -6.56459  1.000 9.95259  ? 76  TRP F CE3 1 
ATOM   2698 C CZ2 . TRP D  1 78 ? -18.50842 7.22455   -8.19101  1.000 12.28465 ? 76  TRP F CZ2 1 
ATOM   2699 C CZ3 . TRP D  1 78 ? -17.74385 4.95172   -7.91409  1.000 12.71435 ? 76  TRP F CZ3 1 
ATOM   2700 C CH2 . TRP D  1 78 ? -17.96853 6.08116   -8.71045  1.000 12.50022 ? 76  TRP F CH2 1 
ATOM   2701 N N   . ASP D  1 79 ? -16.40326 7.76713   -2.92180  1.000 9.89666  ? 77  ASP F N   1 
ATOM   2702 C CA  . ASP D  1 79 ? -16.10011 9.16446   -2.64871  1.000 12.23003 ? 77  ASP F CA  1 
ATOM   2703 C C   . ASP D  1 79 ? -15.84797 9.91638   -3.94752  1.000 12.82011 ? 77  ASP F C   1 
ATOM   2704 O O   . ASP D  1 79 ? -15.08487 10.88461  -3.97714  1.000 17.90706 ? 77  ASP F O   1 
ATOM   2705 C CB  . ASP D  1 79 ? -14.92749 9.29095   -1.67824  1.000 12.54944 ? 77  ASP F CB  1 
ATOM   2706 C CG  . ASP D  1 79 ? -15.19122 8.57162   -0.36841  1.000 13.76603 ? 77  ASP F CG  1 
ATOM   2707 O OD1 . ASP D  1 79 ? -16.01349 9.05697   0.43187   1.000 11.82249 ? 77  ASP F OD1 1 
ATOM   2708 O OD2 . ASP D  1 79 ? -14.60317 7.49362   -0.15095  1.000 15.25310 ? 77  ASP F OD2 1 
ATOM   2709 N N   . GLY D  1 80 ? -16.47616 9.46691   -5.03085  1.000 12.49915 ? 78  GLY F N   1 
ATOM   2710 C CA  . GLY D  1 80 ? -16.41406 10.14186  -6.31089  1.000 16.22609 ? 78  GLY F CA  1 
ATOM   2711 C C   . GLY D  1 80 ? -15.44461 9.57134   -7.32500  1.000 16.75765 ? 78  GLY F C   1 
ATOM   2712 O O   . GLY D  1 80 ? -15.39993 10.07466  -8.45478  1.000 23.05252 ? 78  GLY F O   1 
ATOM   2713 N N   . ASN D  1 81 ? -14.66974 8.55122   -6.97365  1.000 15.18740 ? 79  ASN F N   1 
ATOM   2714 C CA  . ASN D  1 81 ? -13.61784 8.05004   -7.85736  1.000 17.31182 ? 79  ASN F CA  1 
ATOM   2715 C C   . ASN D  1 81 ? -13.42841 6.54537   -7.66151  1.000 15.54863 ? 79  ASN F C   1 
ATOM   2716 O O   . ASN D  1 81 ? -12.33934 6.04742   -7.38171  1.000 19.96223 ? 79  ASN F O   1 
ATOM   2717 C CB  . ASN D  1 81 ? -12.31845 8.82400   -7.63966  1.000 26.52744 ? 79  ASN F CB  1 
ATOM   2718 C CG  . ASN D  1 81 ? -11.21463 8.41152   -8.60902  1.000 41.01484 ? 79  ASN F CG  1 
ATOM   2719 O OD1 . ASN D  1 81 ? -11.46408 8.17351   -9.79309  1.000 36.35490 ? 79  ASN F OD1 1 
ATOM   2720 N ND2 . ASN D  1 81 ? -9.98890  8.31174   -8.10117  1.000 33.00461 ? 79  ASN F ND2 1 
ATOM   2721 N N   . GLY D  1 82 ? -14.50076 5.78662   -7.82653  1.000 13.88947 ? 80  GLY F N   1 
ATOM   2722 C CA  . GLY D  1 82 ? -14.43687 4.34847   -7.70222  1.000 11.47269 ? 80  GLY F CA  1 
ATOM   2723 C C   . GLY D  1 82 ? -14.65458 3.88126   -6.27313  1.000 10.09569 ? 80  GLY F C   1 
ATOM   2724 O O   . GLY D  1 82 ? -14.54993 4.63810   -5.30921  1.000 12.35739 ? 80  GLY F O   1 
ATOM   2725 N N   . TRP D  1 83 ? -14.96936 2.60316   -6.14829  1.000 8.63718  ? 81  TRP F N   1 
ATOM   2726 C CA  . TRP D  1 83 ? -15.18330 1.99957   -4.84594  1.000 9.41333  ? 81  TRP F CA  1 
ATOM   2727 C C   . TRP D  1 83 ? -13.85357 1.55437   -4.25231  1.000 8.17074  ? 81  TRP F C   1 
ATOM   2728 O O   . TRP D  1 83 ? -13.06650 0.87167   -4.91781  1.000 11.16565 ? 81  TRP F O   1 
ATOM   2729 C CB  . TRP D  1 83 ? -16.12720 0.81107   -4.98219  1.000 8.19541  ? 81  TRP F CB  1 
ATOM   2730 C CG  . TRP D  1 83 ? -17.51588 1.24472   -5.29774  1.000 8.15885  ? 81  TRP F CG  1 
ATOM   2731 C CD1 . TRP D  1 83 ? -18.07731 1.38032   -6.53502  1.000 9.28581  ? 81  TRP F CD1 1 
ATOM   2732 C CD2 . TRP D  1 83 ? -18.51825 1.63150   -4.35357  1.000 8.20618  ? 81  TRP F CD2 1 
ATOM   2733 N NE1 . TRP D  1 83 ? -19.37424 1.81203   -6.41741  1.000 8.80735  ? 81  TRP F NE1 1 
ATOM   2734 C CE2 . TRP D  1 83 ? -19.66864 1.98205   -5.08882  1.000 6.64971  ? 81  TRP F CE2 1 
ATOM   2735 C CE3 . TRP D  1 83 ? -18.55706 1.71050   -2.95519  1.000 7.50863  ? 81  TRP F CE3 1 
ATOM   2736 C CZ2 . TRP D  1 83 ? -20.85461 2.38311   -4.47287  1.000 7.67794  ? 81  TRP F CZ2 1 
ATOM   2737 C CZ3 . TRP D  1 83 ? -19.73144 2.11431   -2.34816  1.000 7.79661  ? 81  TRP F CZ3 1 
ATOM   2738 C CH2 . TRP D  1 83 ? -20.86550 2.44358   -3.10305  1.000 7.51161  ? 81  TRP F CH2 1 
ATOM   2739 N N   . THR D  1 84 ? -13.60552 1.94178   -3.00454  1.000 9.05648  ? 82  THR F N   1 
ATOM   2740 C CA  . THR D  1 84 ? -12.36937 1.60593   -2.31170  1.000 9.86003  ? 82  THR F CA  1 
ATOM   2741 C C   . THR D  1 84 ? -12.69469 0.88965   -1.00690  1.000 8.42223  ? 82  THR F C   1 
ATOM   2742 O O   . THR D  1 84 ? -13.74978 1.10987   -0.40663  1.000 8.54264  ? 82  THR F O   1 
ATOM   2743 C CB  . THR D  1 84 ? -11.53994 2.86535   -1.99390  1.000 10.97713 ? 82  THR F CB  1 
ATOM   2744 O OG1 . THR D  1 84 ? -12.22847 3.67903   -1.03617  1.000 12.70476 ? 82  THR F OG1 1 
ATOM   2745 C CG2 . THR D  1 84 ? -11.29047 3.68215   -3.25728  1.000 15.37005 ? 82  THR F CG2 1 
ATOM   2746 N N   . LYS D  1 85 ? -11.78170 0.04502   -0.54414  1.000 8.63839  ? 83  LYS F N   1 
ATOM   2747 C CA  . LYS D  1 85 ? -12.01571 -0.65140  0.70972   1.000 9.12352  ? 83  LYS F CA  1 
ATOM   2748 C C   . LYS D  1 85 ? -11.75955 0.30274   1.86779   1.000 7.90660  ? 83  LYS F C   1 
ATOM   2749 O O   . LYS D  1 85 ? -10.71840 0.96050   1.92481   1.000 9.83360  ? 83  LYS F O   1 
ATOM   2750 C CB  . LYS D  1 85 ? -11.12659 -1.88690  0.82142   1.000 13.27362 ? 83  LYS F CB  1 
ATOM   2751 C CG  . LYS D  1 85 ? -11.51213 -2.79784  1.97315   1.000 15.97312 ? 83  LYS F CG  1 
ATOM   2752 C CD  . LYS D  1 85 ? -10.72202 -4.10017  1.95082   1.000 25.92026 ? 83  LYS F CD  1 
ATOM   2753 C CE  . LYS D  1 85 ? -11.07904 -4.94402  0.73618   1.000 32.29632 ? 83  LYS F CE  1 
ATOM   2754 N NZ  . LYS D  1 85 ? -10.43434 -6.29093  0.76713   1.000 47.39357 ? 83  LYS F NZ  1 
ATOM   2755 N N   . GLY D  1 86 ? -12.71143 0.38948   2.78683   1.000 8.28832  ? 84  GLY F N   1 
ATOM   2756 C CA  . GLY D  1 86 ? -12.58478 1.28434   3.91705   1.000 8.20127  ? 84  GLY F CA  1 
ATOM   2757 C C   . GLY D  1 86 ? -11.85143 0.65554   5.07425   1.000 7.25373  ? 84  GLY F C   1 
ATOM   2758 O O   . GLY D  1 86 ? -11.56855 -0.53945  5.07605   1.000 8.88063  ? 84  GLY F O   1 
ATOM   2759 N N   . ALA D  1 87 ? -11.58294 1.48137   6.08170   1.000 7.24940  ? 85  ALA F N   1 
ATOM   2760 C CA  . ALA D  1 87 ? -10.82787 1.04014   7.24575   1.000 8.04543  ? 85  ALA F CA  1 
ATOM   2761 C C   . ALA D  1 87 ? -11.63724 0.20524   8.22997   1.000 7.65959  ? 85  ALA F C   1 
ATOM   2762 O O   . ALA D  1 87 ? -11.03721 -0.37378  9.14037   1.000 8.50918  ? 85  ALA F O   1 
ATOM   2763 C CB  . ALA D  1 87 ? -10.27292 2.25174   7.99315   1.000 8.93644  ? 85  ALA F CB  1 
ATOM   2764 N N   . TYR D  1 88 ? -12.96352 0.13712   8.08713   1.000 7.03858  ? 86  TYR F N   1 
ATOM   2765 C CA  . TYR D  1 88 ? -13.79574 -0.54795  9.06984   1.000 7.42547  ? 86  TYR F CA  1 
ATOM   2766 C C   . TYR D  1 88 ? -13.25027 -1.92512  9.41011   1.000 7.29150  ? 86  TYR F C   1 
ATOM   2767 O O   . TYR D  1 88 ? -12.94830 -2.73015  8.52610   1.000 7.98803  ? 86  TYR F O   1 
ATOM   2768 C CB  . TYR D  1 88 ? -15.20814 -0.71636  8.51463   1.000 7.32402  ? 86  TYR F CB  1 
ATOM   2769 C CG  . TYR D  1 88 ? -16.13932 -1.47820  9.43823   1.000 7.25055  ? 86  TYR F CG  1 
ATOM   2770 C CD1 . TYR D  1 88 ? -16.24946 -2.86178  9.36906   1.000 7.84251  ? 86  TYR F CD1 1 
ATOM   2771 C CD2 . TYR D  1 88 ? -16.90022 -0.80833  10.38539  1.000 7.62266  ? 86  TYR F CD2 1 
ATOM   2772 C CE1 . TYR D  1 88 ? -17.08764 -3.55483  10.22166  1.000 8.71705  ? 86  TYR F CE1 1 
ATOM   2773 C CE2 . TYR D  1 88 ? -17.74412 -1.49340  11.23778  1.000 8.09275  ? 86  TYR F CE2 1 
ATOM   2774 C CZ  . TYR D  1 88 ? -17.83405 -2.85707  11.15349  1.000 8.10007  ? 86  TYR F CZ  1 
ATOM   2775 O OH  . TYR D  1 88 ? -18.68527 -3.51140  12.01420  1.000 9.42474  ? 86  TYR F OH  1 
ATOM   2776 N N   . THR D  1 89 ? -13.17000 -2.19965  10.70645  1.000 7.94472  ? 87  THR F N   1 
ATOM   2777 C CA  . THR D  1 89 ? -12.96628 -3.53936  11.22671  1.000 9.08158  ? 87  THR F CA  1 
ATOM   2778 C C   . THR D  1 89 ? -13.96096 -3.76768  12.35009  1.000 8.99267  ? 87  THR F C   1 
ATOM   2779 O O   . THR D  1 89 ? -14.44422 -2.82555  12.98038  1.000 9.28969  ? 87  THR F O   1 
ATOM   2780 C CB  . THR D  1 89 ? -11.55922 -3.74317  11.80599  1.000 10.58455 ? 87  THR F CB  1 
ATOM   2781 O OG1 . THR D  1 89 ? -11.32874 -2.77840  12.83720  1.000 11.93058 ? 87  THR F OG1 1 
ATOM   2782 C CG2 . THR D  1 89 ? -10.49078 -3.61516  10.72418  1.000 11.73791 ? 87  THR F CG2 1 
ATOM   2783 N N   . ALA D  1 90 ? -14.25611 -5.04697  12.57518  1.000 11.49869 ? 88  ALA F N   1 
ATOM   2784 C CA  . ALA D  1 90 ? -15.05079 -5.52241  13.69486  1.000 15.60417 ? 88  ALA F CA  1 
ATOM   2785 C C   . ALA D  1 90 ? -14.50925 -6.88909  14.08802  1.000 30.59365 ? 88  ALA F C   1 
ATOM   2786 O O   . ALA D  1 90 ? -13.80954 -7.54379  13.31080  1.000 37.62049 ? 88  ALA F O   1 
ATOM   2787 C CB  . ALA D  1 90 ? -16.52847 -5.63921  13.31740  1.000 21.16494 ? 88  ALA F CB  1 
ATOM   2788 N N   . THR D  1 91 ? -14.83746 -7.32035  15.30336  1.000 40.46207 ? 89  THR F N   1 
ATOM   2789 C CA  . THR D  1 91 ? -14.39350 -8.61458  15.82398  1.000 39.22300 ? 89  THR F CA  1 
ATOM   2790 C C   . THR D  1 91 ? -15.62802 -9.48437  16.04636  1.000 39.12198 ? 89  THR F C   1 
ATOM   2791 O O   . THR D  1 91 ? -16.12366 -9.61592  17.16775  1.000 48.58987 ? 89  THR F O   1 
ATOM   2792 C CB  . THR D  1 91 ? -13.57604 -8.43239  17.10947  1.000 50.70053 ? 89  THR F CB  1 
ATOM   2793 O OG1 . THR D  1 91 ? -12.57530 -7.42846  16.89986  1.000 51.14587 ? 89  THR F OG1 1 
ATOM   2794 C CG2 . THR D  1 91 ? -12.89467 -9.73926  17.49573  1.000 51.78057 ? 89  THR F CG2 1 
ATOM   2795 N N   . ASN D  1 92 ? -16.12382 -10.07973 14.96625  1.000 28.34749 ? 90  ASN F N   1 
ATOM   2796 C CA  . ASN D  1 92 ? -17.31940 -10.91310 15.03642  1.000 40.77951 ? 90  ASN F CA  1 
ATOM   2797 C C   . ASN D  1 92 ? -16.94742 -12.38845 15.17616  1.000 43.52971 ? 90  ASN F C   1 
ATOM   2798 O O   . ASN D  1 92 ? -17.76026 -13.20824 15.60849  1.000 35.31803 ? 90  ASN F O   1 
ATOM   2799 C CB  . ASN D  1 92 ? -18.19793 -10.70527 13.79744  1.000 31.71040 ? 90  ASN F CB  1 
ATOM   2800 C CG  . ASN D  1 92 ? -18.60551 -9.25455  13.60097  1.000 22.74358 ? 90  ASN F CG  1 
ATOM   2801 O OD1 . ASN D  1 92 ? -18.98648 -8.56990  14.54899  1.000 23.61620 ? 90  ASN F OD1 1 
ATOM   2802 N ND2 . ASN D  1 92 ? -18.52198 -8.77810  12.36329  1.000 20.32118 ? 90  ASN F ND2 1 
ATOM   2803 N N   . ALA E  1 3  ? -24.93211 -18.86109 9.66365   1.000 39.94651 ? 1   ALA D N   1 
ATOM   2804 C CA  . ALA E  1 3  ? -25.56648 -17.64468 9.16920   1.000 39.60659 ? 1   ALA D CA  1 
ATOM   2805 C C   . ALA E  1 3  ? -24.59187 -16.48135 9.19165   1.000 32.63935 ? 1   ALA D C   1 
ATOM   2806 O O   . ALA E  1 3  ? -23.91141 -16.26091 10.19211  1.000 25.23435 ? 1   ALA D O   1 
ATOM   2807 C CB  . ALA E  1 3  ? -26.76492 -17.30676 10.01649  1.000 43.25734 ? 1   ALA D CB  1 
ATOM   2808 N N   . SER E  1 4  ? -24.53278 -15.72708 8.09676   1.000 19.55675 ? 2   SER D N   1 
ATOM   2809 C CA  . SER E  1 4  ? -23.73496 -14.51121 8.09766   1.000 16.15692 ? 2   SER D CA  1 
ATOM   2810 C C   . SER E  1 4  ? -24.32536 -13.50780 9.08467   1.000 14.94233 ? 2   SER D C   1 
ATOM   2811 O O   . SER E  1 4  ? -25.53786 -13.46964 9.32236   1.000 17.19046 ? 2   SER D O   1 
ATOM   2812 C CB  . SER E  1 4  ? -23.69115 -13.89935 6.69455   1.000 17.76324 ? 2   SER D CB  1 
ATOM   2813 O OG  . SER E  1 4  ? -22.96956 -14.72136 5.78550   1.000 14.61945 ? 2   SER D OG  1 
ATOM   2814 N N   . VAL E  1 5  ? -23.44773 -12.70152 9.68503   1.000 12.53745 ? 3   VAL D N   1 
ATOM   2815 C CA  . VAL E  1 5  ? -23.92440 -11.60136 10.51259  1.000 10.93633 ? 3   VAL D CA  1 
ATOM   2816 C C   . VAL E  1 5  ? -24.77003 -10.64754 9.66567   1.000 10.20779 ? 3   VAL D C   1 
ATOM   2817 O O   . VAL E  1 5  ? -24.69697 -10.62564 8.43008   1.000 12.33828 ? 3   VAL D O   1 
ATOM   2818 C CB  . VAL E  1 5  ? -22.75687 -10.87191 11.19738  1.000 11.11943 ? 3   VAL D CB  1 
ATOM   2819 C CG1 . VAL E  1 5  ? -21.95628 -11.84723 12.05832  1.000 12.61860 ? 3   VAL D CG1 1 
ATOM   2820 C CG2 . VAL E  1 5  ? -21.85582 -10.19041 10.16693  1.000 12.31758 ? 3   VAL D CG2 1 
ATOM   2821 N N   A GLN E  1 6  ? -25.60134 -9.87587  10.35447  0.562 8.82561  ? 4   GLN D N   1 
ATOM   2822 N N   B GLN E  1 6  ? -25.57893 -9.83695  10.34424  0.438 8.81266  ? 4   GLN D N   1 
ATOM   2823 C CA  A GLN E  1 6  ? -26.48795 -8.89518  9.75311   0.562 10.24580 ? 4   GLN D CA  1 
ATOM   2824 C CA  B GLN E  1 6  ? -26.48765 -8.90692  9.67961   0.438 10.32944 ? 4   GLN D CA  1 
ATOM   2825 C C   A GLN E  1 6  ? -26.06649 -7.52707  10.26393  0.562 8.50757  ? 4   GLN D C   1 
ATOM   2826 C C   B GLN E  1 6  ? -26.27796 -7.51730  10.26207  0.438 9.09040  ? 4   GLN D C   1 
ATOM   2827 O O   A GLN E  1 6  ? -25.71554 -7.37905  11.43865  0.562 8.05553  ? 4   GLN D O   1 
ATOM   2828 O O   B GLN E  1 6  ? -26.29867 -7.34971  11.48539  0.438 7.78136  ? 4   GLN D O   1 
ATOM   2829 C CB  A GLN E  1 6  ? -27.93453 -9.16158  10.18150  0.562 12.45070 ? 4   GLN D CB  1 
ATOM   2830 C CB  B GLN E  1 6  ? -27.94743 -9.34852  9.85434   0.438 12.06990 ? 4   GLN D CB  1 
ATOM   2831 C CG  A GLN E  1 6  ? -28.35488 -10.62134 10.08838  0.562 14.08399 ? 4   GLN D CG  1 
ATOM   2832 C CG  B GLN E  1 6  ? -28.97329 -8.51894  9.08779   0.438 11.67986 ? 4   GLN D CG  1 
ATOM   2833 C CD  A GLN E  1 6  ? -28.63536 -11.06200 8.66946   0.562 17.59895 ? 4   GLN D CD  1 
ATOM   2834 C CD  B GLN E  1 6  ? -29.58933 -7.42098  9.92742   0.438 13.59080 ? 4   GLN D CD  1 
ATOM   2835 O OE1 A GLN E  1 6  ? -29.62932 -10.65807 8.06994   0.562 17.92246 ? 4   GLN D OE1 1 
ATOM   2836 O OE1 B GLN E  1 6  ? -29.69838 -7.55147  11.14173  0.438 11.31153 ? 4   GLN D OE1 1 
ATOM   2837 N NE2 A GLN E  1 6  ? -27.75818 -11.89738 8.12231   0.562 15.33827 ? 4   GLN D NE2 1 
ATOM   2838 N NE2 B GLN E  1 6  ? -30.00031 -6.33435  9.28306   0.438 12.48378 ? 4   GLN D NE2 1 
ATOM   2839 N N   . THR E  1 7  ? -26.08246 -6.52498  9.39126   1.000 8.19390  ? 5   THR D N   1 
ATOM   2840 C CA  . THR E  1 7  ? -25.70691 -5.18465  9.81218   1.000 7.60994  ? 5   THR D CA  1 
ATOM   2841 C C   . THR E  1 7  ? -26.74636 -4.13574  9.44355   1.000 7.00482  ? 5   THR D C   1 
ATOM   2842 O O   . THR E  1 7  ? -27.63063 -4.33733  8.60473   1.000 7.78314  ? 5   THR D O   1 
ATOM   2843 C CB  . THR E  1 7  ? -24.33312 -4.73930  9.28022   1.000 7.73146  ? 5   THR D CB  1 
ATOM   2844 O OG1 . THR E  1 7  ? -24.41167 -4.46088  7.87514   1.000 8.44767  ? 5   THR D OG1 1 
ATOM   2845 C CG2 . THR E  1 7  ? -23.24790 -5.77644  9.57717   1.000 9.07050  ? 5   THR D CG2 1 
ATOM   2846 N N   . ALA E  1 8  ? -26.60503 -2.99613  10.10638  1.000 6.49363  ? 6   ALA D N   1 
ATOM   2847 C CA  . ALA E  1 8  ? -27.35439 -1.78560  9.82344   1.000 6.45698  ? 6   ALA D CA  1 
ATOM   2848 C C   . ALA E  1 8  ? -26.41023 -0.61798  10.05449  1.000 5.98676  ? 6   ALA D C   1 
ATOM   2849 O O   . ALA E  1 8  ? -25.55183 -0.67710  10.94119  1.000 7.94394  ? 6   ALA D O   1 
ATOM   2850 C CB  . ALA E  1 8  ? -28.56942 -1.67570  10.74956  1.000 7.65726  ? 6   ALA D CB  1 
ATOM   2851 N N   . ALA E  1 9  ? -26.57126 0.44305   9.26935   1.000 5.85193  ? 7   ALA D N   1 
ATOM   2852 C CA  . ALA E  1 9  ? -25.64787 1.56384   9.33772   1.000 6.57365  ? 7   ALA D CA  1 
ATOM   2853 C C   . ALA E  1 9  ? -26.39512 2.88395   9.25713   1.000 5.82748  ? 7   ALA D C   1 
ATOM   2854 O O   . ALA E  1 9  ? -27.39363 3.00865   8.54729   1.000 6.56750  ? 7   ALA D O   1 
ATOM   2855 C CB  . ALA E  1 9  ? -24.63546 1.49991   8.18703   1.000 7.33068  ? 7   ALA D CB  1 
ATOM   2856 N N   . THR E  1 10 ? -25.88186 3.87804   9.96980   1.000 6.13155  ? 8   THR D N   1 
ATOM   2857 C CA  . THR E  1 10 ? -26.37792 5.23895   9.85035   1.000 6.21047  ? 8   THR D CA  1 
ATOM   2858 C C   . THR E  1 10 ? -25.19323 6.19193   9.93895   1.000 6.18604  ? 8   THR D C   1 
ATOM   2859 O O   . THR E  1 10 ? -24.10123 5.80627   10.36417  1.000 7.23678  ? 8   THR D O   1 
ATOM   2860 C CB  . THR E  1 10 ? -27.46519 5.54102   10.90194  1.000 7.18933  ? 8   THR D CB  1 
ATOM   2861 O OG1 . THR E  1 10 ? -28.13750 6.75762   10.56446  1.000 8.72747  ? 8   THR D OG1 1 
ATOM   2862 C CG2 . THR E  1 10 ? -26.86386 5.69223   12.29186  1.000 8.49871  ? 8   THR D CG2 1 
ATOM   2863 N N   . SER E  1 11 ? -25.40995 7.44564   9.54396   1.000 6.25580  ? 9   SER D N   1 
ATOM   2864 C CA  . SER E  1 11 ? -24.34212 8.43582   9.54944   1.000 6.67578  ? 9   SER D CA  1 
ATOM   2865 C C   . SER E  1 11 ? -24.95238 9.82298   9.66587   1.000 6.75835  ? 9   SER D C   1 
ATOM   2866 O O   . SER E  1 11 ? -26.13269 10.02441  9.35623   1.000 7.12435  ? 9   SER D O   1 
ATOM   2867 C CB  . SER E  1 11 ? -23.48181 8.34579   8.28311   1.000 7.31227  ? 9   SER D CB  1 
ATOM   2868 O OG  . SER E  1 11 ? -24.25911 8.58533   7.11466   1.000 7.62066  ? 9   SER D OG  1 
ATOM   2869 N N   . TRP E  1 12 ? -24.13559 10.79031  10.09467  1.000 6.99851  ? 10  TRP D N   1 
ATOM   2870 C CA  . TRP E  1 12 ? -24.62374 12.15452  10.23520  1.000 7.45173  ? 10  TRP D CA  1 
ATOM   2871 C C   . TRP E  1 12 ? -23.49185 13.16084  10.10584  1.000 7.86346  ? 10  TRP D C   1 
ATOM   2872 O O   . TRP E  1 12 ? -22.32310 12.86729  10.37519  1.000 7.94765  ? 10  TRP D O   1 
ATOM   2873 C CB  . TRP E  1 12 ? -25.37690 12.37933  11.54116  1.000 8.10484  ? 10  TRP D CB  1 
ATOM   2874 C CG  . TRP E  1 12 ? -24.58859 12.18541  12.79337  1.000 7.82482  ? 10  TRP D CG  1 
ATOM   2875 C CD1 . TRP E  1 12 ? -23.92018 13.14683  13.49701  1.000 9.16653  ? 10  TRP D CD1 1 
ATOM   2876 C CD2 . TRP E  1 12 ? -24.44041 10.96972  13.53315  1.000 7.43441  ? 10  TRP D CD2 1 
ATOM   2877 N NE1 . TRP E  1 12 ? -23.35610 12.60164  14.62199  1.000 8.96418  ? 10  TRP D NE1 1 
ATOM   2878 C CE2 . TRP E  1 12 ? -23.67060 11.26861  14.67715  1.000 8.92946  ? 10  TRP D CE2 1 
ATOM   2879 C CE3 . TRP E  1 12 ? -24.89641 9.65989   13.34643  1.000 7.71646  ? 10  TRP D CE3 1 
ATOM   2880 C CZ2 . TRP E  1 12 ? -23.31962 10.29619  15.61856  1.000 8.97398  ? 10  TRP D CZ2 1 
ATOM   2881 C CZ3 . TRP E  1 12 ? -24.55591 8.69951   14.28323  1.000 8.29111  ? 10  TRP D CZ3 1 
ATOM   2882 C CH2 . TRP E  1 12 ? -23.78132 9.02348   15.40984  1.000 9.12692  ? 10  TRP D CH2 1 
ATOM   2883 N N   . GLY E  1 13 ? -23.87011 14.37014  9.70464   1.000 9.04491  ? 11  GLY D N   1 
ATOM   2884 C CA  . GLY E  1 13 ? -22.92078 15.45051  9.56489   1.000 9.31178  ? 11  GLY D CA  1 
ATOM   2885 C C   . GLY E  1 13 ? -22.00817 15.26781  8.36214   1.000 9.83622  ? 11  GLY D C   1 
ATOM   2886 O O   . GLY E  1 13 ? -22.24187 14.45180  7.46727   1.000 11.93039 ? 11  GLY D O   1 
ATOM   2887 N N   . THR E  1 14 ? -20.94304 16.07327  8.34714   1.000 10.10228 ? 12  THR D N   1 
ATOM   2888 C CA  . THR E  1 14 ? -20.00125 16.07313  7.23736   1.000 11.63683 ? 12  THR D CA  1 
ATOM   2889 C C   . THR E  1 14 ? -18.64311 15.48011  7.57088   1.000 11.33336 ? 12  THR D C   1 
ATOM   2890 O O   . THR E  1 14 ? -17.82588 15.32131  6.65987   1.000 13.42903 ? 12  THR D O   1 
ATOM   2891 C CB  . THR E  1 14 ? -19.81170 17.48821  6.66623   1.000 12.75310 ? 12  THR D CB  1 
ATOM   2892 O OG1 . THR E  1 14 ? -19.38887 18.37432  7.70908   1.000 14.71761 ? 12  THR D OG1 1 
ATOM   2893 C CG2 . THR E  1 14 ? -21.11393 17.98839  6.07207   1.000 12.76677 ? 12  THR D CG2 1 
ATOM   2894 N N   . VAL E  1 15 ? -18.36830 15.15501  8.83458   1.000 12.22879 ? 13  VAL D N   1 
ATOM   2895 C CA  . VAL E  1 15 ? -17.10571 14.48883  9.15986   1.000 11.47532 ? 13  VAL D CA  1 
ATOM   2896 C C   . VAL E  1 15 ? -16.92228 13.18801  8.38447   1.000 10.98190 ? 13  VAL D C   1 
ATOM   2897 O O   . VAL E  1 15 ? -15.86459 13.01350  7.75877   1.000 13.01268 ? 13  VAL D O   1 
ATOM   2898 C CB  . VAL E  1 15 ? -16.94187 14.34765  10.68325  1.000 12.73957 ? 13  VAL D CB  1 
ATOM   2899 C CG1 . VAL E  1 15 ? -15.66899 13.58550  11.00816  1.000 14.67178 ? 13  VAL D CG1 1 
ATOM   2900 C CG2 . VAL E  1 15 ? -16.93694 15.71554  11.35191  1.000 15.24775 ? 13  VAL D CG2 1 
ATOM   2901 N N   . PRO E  1 16 ? -17.87790 12.24373  8.37928   1.000 10.37514 ? 14  PRO D N   1 
ATOM   2902 C CA  . PRO E  1 16 ? -19.11963 12.19679  9.14856   1.000 9.25152  ? 14  PRO D CA  1 
ATOM   2903 C C   . PRO E  1 16 ? -18.87176 11.38989  10.40633  1.000 8.29470  ? 14  PRO D C   1 
ATOM   2904 O O   . PRO E  1 16 ? -17.78149 10.84975  10.63048  1.000 9.58130  ? 14  PRO D O   1 
ATOM   2905 C CB  . PRO E  1 16 ? -20.02877 11.39402  8.22310   1.000 9.72000  ? 14  PRO D CB  1 
ATOM   2906 C CG  . PRO E  1 16 ? -19.09782 10.33120  7.72598   1.000 11.20652 ? 14  PRO D CG  1 
ATOM   2907 C CD  . PRO E  1 16 ? -17.77697 11.06394  7.49838   1.000 10.88342 ? 14  PRO D CD  1 
ATOM   2908 N N   . SER E  1 17 ? -19.88786 11.29356  11.24721  1.000 7.69595  ? 15  SER D N   1 
ATOM   2909 C CA  . SER E  1 17 ? -19.98046 10.20269  12.19781  1.000 7.29178  ? 15  SER D CA  1 
ATOM   2910 C C   . SER E  1 17 ? -20.74776 9.06601   11.53886  1.000 6.56747  ? 15  SER D C   1 
ATOM   2911 O O   . SER E  1 17 ? -21.71395 9.30028   10.80656  1.000 7.32585  ? 15  SER D O   1 
ATOM   2912 C CB  . SER E  1 17 ? -20.70622 10.64237  13.46166  1.000 8.28880  ? 15  SER D CB  1 
ATOM   2913 O OG  . SER E  1 17 ? -19.88381 11.45746  14.27221  1.000 9.92425  ? 15  SER D OG  1 
ATOM   2914 N N   . ILE E  1 18 ? -20.29869 7.83650   11.78065  1.000 6.01613  ? 16  ILE D N   1 
ATOM   2915 C CA  . ILE E  1 18 ? -20.94614 6.63161   11.27902  1.000 6.15435  ? 16  ILE D CA  1 
ATOM   2916 C C   . ILE E  1 18 ? -21.12989 5.69500   12.46004  1.000 6.61817  ? 16  ILE D C   1 
ATOM   2917 O O   . ILE E  1 18 ? -20.25472 5.60756   13.33263  1.000 6.32017  ? 16  ILE D O   1 
ATOM   2918 C CB  . ILE E  1 18 ? -20.11546 5.91879   10.18370  1.000 6.53820  ? 16  ILE D CB  1 
ATOM   2919 C CG1 . ILE E  1 18 ? -19.65105 6.89645   9.10122   1.000 8.30026  ? 16  ILE D CG1 1 
ATOM   2920 C CG2 . ILE E  1 18 ? -20.91785 4.77408   9.56713   1.000 7.74845  ? 16  ILE D CG2 1 
ATOM   2921 C CD1 . ILE E  1 18 ? -18.60076 6.32394   8.16292   1.000 8.77675  ? 16  ILE D CD1 1 
ATOM   2922 N N   . ARG E  1 19 ? -22.25820 4.98832   12.48664  1.000 5.88155  ? 17  ARG D N   1 
ATOM   2923 C CA  . ARG E  1 19 ? -22.46628 3.89663   13.42845  1.000 5.76977  ? 17  ARG D CA  1 
ATOM   2924 C C   . ARG E  1 19 ? -22.90752 2.67155   12.64547  1.000 5.45141  ? 17  ARG D C   1 
ATOM   2925 O O   . ARG E  1 19 ? -23.80234 2.76572   11.79417  1.000 6.71392  ? 17  ARG D O   1 
ATOM   2926 C CB  . ARG E  1 19 ? -23.52289 4.25509   14.48060  1.000 6.28724  ? 17  ARG D CB  1 
ATOM   2927 C CG  . ARG E  1 19 ? -23.16455 5.46350   15.33345  1.000 6.73969  ? 17  ARG D CG  1 
ATOM   2928 C CD  . ARG E  1 19 ? -21.95779 5.20636   16.23320  1.000 7.12774  ? 17  ARG D CD  1 
ATOM   2929 N NE  . ARG E  1 19 ? -21.65154 6.34175   17.10249  1.000 7.12597  ? 17  ARG D NE  1 
ATOM   2930 C CZ  . ARG E  1 19 ? -20.81962 7.33260   16.80203  1.000 7.43644  ? 17  ARG D CZ  1 
ATOM   2931 N NH1 . ARG E  1 19 ? -20.18997 7.38137   15.64173  1.000 8.00901  ? 17  ARG D NH1 1 
ATOM   2932 N NH2 . ARG E  1 19 ? -20.60739 8.29643   17.69584  1.000 9.12562  ? 17  ARG D NH2 1 
ATOM   2933 N N   . VAL E  1 20 ? -22.26876 1.53338   12.91653  1.000 5.65562  ? 18  VAL D N   1 
ATOM   2934 C CA  . VAL E  1 20 ? -22.57691 0.26583   12.26822  1.000 6.51615  ? 18  VAL D CA  1 
ATOM   2935 C C   . VAL E  1 20 ? -22.94325 -0.72896  13.35679  1.000 6.31837  ? 18  VAL D C   1 
ATOM   2936 O O   . VAL E  1 20 ? -22.15309 -0.96148  14.28246  1.000 6.28995  ? 18  VAL D O   1 
ATOM   2937 C CB  . VAL E  1 20 ? -21.39060 -0.25360  11.44272  1.000 6.56498  ? 18  VAL D CB  1 
ATOM   2938 C CG1 . VAL E  1 20 ? -21.74113 -1.58529  10.79020  1.000 7.95549  ? 18  VAL D CG1 1 
ATOM   2939 C CG2 . VAL E  1 20 ? -20.96997 0.76362   10.38706  1.000 7.75855  ? 18  VAL D CG2 1 
ATOM   2940 N N   . TYR E  1 21 ? -24.14271 -1.29206  13.25709  1.000 6.37671  ? 19  TYR D N   1 
ATOM   2941 C CA  . TYR E  1 21 ? -24.67090 -2.25689  14.21230  1.000 6.45864  ? 19  TYR D CA  1 
ATOM   2942 C C   . TYR E  1 21 ? -24.59219 -3.63613  13.58051  1.000 6.86206  ? 19  TYR D C   1 
ATOM   2943 O O   . TYR E  1 21 ? -24.98017 -3.81127  12.41997  1.000 7.77537  ? 19  TYR D O   1 
ATOM   2944 C CB  . TYR E  1 21 ? -26.13284 -1.91170  14.56655  1.000 7.59224  ? 19  TYR D CB  1 
ATOM   2945 C CG  . TYR E  1 21 ? -26.19547 -0.52833  15.14680  1.000 6.42282  ? 19  TYR D CG  1 
ATOM   2946 C CD1 . TYR E  1 21 ? -26.01549 -0.31384  16.50223  1.000 7.00180  ? 19  TYR D CD1 1 
ATOM   2947 C CD2 . TYR E  1 21 ? -26.31548 0.57995   14.32502  1.000 7.16029  ? 19  TYR D CD2 1 
ATOM   2948 C CE1 . TYR E  1 21 ? -25.98625 0.95305   17.02539  1.000 6.85009  ? 19  TYR D CE1 1 
ATOM   2949 C CE2 . TYR E  1 21 ? -26.27171 1.85376   14.83548  1.000 6.83427  ? 19  TYR D CE2 1 
ATOM   2950 C CZ  . TYR E  1 21 ? -26.10678 2.03940   16.18291  1.000 7.20089  ? 19  TYR D CZ  1 
ATOM   2951 O OH  . TYR E  1 21 ? -26.04289 3.32483   16.66733  1.000 7.50570  ? 19  TYR D OH  1 
ATOM   2952 N N   . THR E  1 22 ? -24.10114 -4.61431  14.33964  1.000 6.21054  ? 20  THR D N   1 
ATOM   2953 C CA  . THR E  1 22 ? -23.93827 -5.97647  13.84679  1.000 7.72797  ? 20  THR D CA  1 
ATOM   2954 C C   . THR E  1 22 ? -24.67351 -6.93187  14.76299  1.000 7.51133  ? 20  THR D C   1 
ATOM   2955 O O   . THR E  1 22 ? -24.39746 -6.96721  15.96505  1.000 8.49808  ? 20  THR D O   1 
ATOM   2956 C CB  . THR E  1 22 ? -22.46055 -6.36736  13.79023  1.000 7.80739  ? 20  THR D CB  1 
ATOM   2957 O OG1 . THR E  1 22 ? -21.76744 -5.49420  12.89903  1.000 8.46678  ? 20  THR D OG1 1 
ATOM   2958 C CG2 . THR E  1 22 ? -22.29329 -7.80000  13.30222  1.000 10.61212 ? 20  THR D CG2 1 
ATOM   2959 N N   . ALA E  1 23 ? -25.59019 -7.70024  14.18668  1.000 7.51230  ? 21  ALA D N   1 
ATOM   2960 C CA  . ALA E  1 23 ? -26.26825 -8.78258  14.88629  1.000 8.67002  ? 21  ALA D CA  1 
ATOM   2961 C C   . ALA E  1 23 ? -25.52231 -10.07826 14.61149  1.000 8.87373  ? 21  ALA D C   1 
ATOM   2962 O O   . ALA E  1 23 ? -25.40057 -10.50084 13.45576  1.000 10.43204 ? 21  ALA D O   1 
ATOM   2963 C CB  . ALA E  1 23 ? -27.71661 -8.90648  14.41913  1.000 10.15878 ? 21  ALA D CB  1 
ATOM   2964 N N   . ASN E  1 24 ? -25.05077 -10.71731 15.67599  1.000 11.08374 ? 22  ASN D N   1 
ATOM   2965 C CA  . ASN E  1 24 ? -24.23638 -11.92118 15.56642  1.000 12.04277 ? 22  ASN D CA  1 
ATOM   2966 C C   . ASN E  1 24 ? -24.58405 -12.81753 16.74301  1.000 11.92941 ? 22  ASN D C   1 
ATOM   2967 O O   . ASN E  1 24 ? -24.44101 -12.40226 17.89558  1.000 12.82565 ? 22  ASN D O   1 
ATOM   2968 C CB  . ASN E  1 24 ? -22.75718 -11.53560 15.61149  1.000 14.45927 ? 22  ASN D CB  1 
ATOM   2969 C CG  . ASN E  1 24 ? -21.83011 -12.72814 15.46434  1.000 17.09708 ? 22  ASN D CG  1 
ATOM   2970 O OD1 . ASN E  1 24 ? -22.25726 -13.82664 15.11129  1.000 20.45700 ? 22  ASN D OD1 1 
ATOM   2971 N ND2 . ASN E  1 24 ? -20.54723 -12.50634 15.71637  1.000 22.81106 ? 22  ASN D ND2 1 
ATOM   2972 N N   . ASN E  1 25 ? -25.04357 -14.03504 16.45146  1.000 14.86132 ? 23  ASN D N   1 
ATOM   2973 C CA  . ASN E  1 25 ? -25.35433 -15.02299 17.48447  1.000 16.94224 ? 23  ASN D CA  1 
ATOM   2974 C C   . ASN E  1 25 ? -26.28624 -14.44487 18.55072  1.000 16.38369 ? 23  ASN D C   1 
ATOM   2975 O O   . ASN E  1 25 ? -26.08544 -14.62822 19.75224  1.000 17.04556 ? 23  ASN D O   1 
ATOM   2976 C CB  . ASN E  1 25 ? -24.07708 -15.60580 18.09425  1.000 19.32929 ? 23  ASN D CB  1 
ATOM   2977 C CG  . ASN E  1 25 ? -24.33698 -16.85779 18.90399  1.000 36.07306 ? 23  ASN D CG  1 
ATOM   2978 O OD1 . ASN E  1 25 ? -23.72965 -17.06929 19.95359  1.000 43.43458 ? 23  ASN D OD1 1 
ATOM   2979 N ND2 . ASN E  1 25 ? -25.25648 -17.68970 18.42704  1.000 42.22362 ? 23  ASN D ND2 1 
ATOM   2980 N N   . GLY E  1 26 ? -27.29500 -13.69593 18.10386  1.000 13.57022 ? 24  GLY D N   1 
ATOM   2981 C CA  . GLY E  1 26 ? -28.31596 -13.18066 18.99197  1.000 13.88531 ? 24  GLY D CA  1 
ATOM   2982 C C   . GLY E  1 26 ? -27.96089 -11.91555 19.73527  1.000 12.56426 ? 24  GLY D C   1 
ATOM   2983 O O   . GLY E  1 26 ? -28.75898 -11.46502 20.56381  1.000 12.64787 ? 24  GLY D O   1 
ATOM   2984 N N   . LYS E  1 27 ? -26.80394 -11.31748 19.45992  1.000 10.98629 ? 25  LYS D N   1 
ATOM   2985 C CA  . LYS E  1 27 ? -26.36164 -10.11133 20.14697  1.000 11.66468 ? 25  LYS D CA  1 
ATOM   2986 C C   . LYS E  1 27 ? -26.04008 -9.03202  19.12803  1.000 9.19800  ? 25  LYS D C   1 
ATOM   2987 O O   . LYS E  1 27 ? -25.37976 -9.30248  18.12368  1.000 10.87700 ? 25  LYS D O   1 
ATOM   2988 C CB  . LYS E  1 27 ? -25.09374 -10.38208 20.96789  1.000 13.83371 ? 25  LYS D CB  1 
ATOM   2989 C CG  . LYS E  1 27 ? -25.27315 -11.36594 22.10756  1.000 19.77427 ? 25  LYS D CG  1 
ATOM   2990 C CD  . LYS E  1 27 ? -23.99954 -11.48428 22.92617  1.000 25.80658 ? 25  LYS D CD  1 
ATOM   2991 C CE  . LYS E  1 27 ? -24.15806 -12.51495 24.02701  1.000 29.79005 ? 25  LYS D CE  1 
ATOM   2992 N NZ  . LYS E  1 27 ? -25.36794 -12.23933 24.85005  1.000 34.31162 ? 25  LYS D NZ  1 
ATOM   2993 N N   . ILE E  1 28 ? -26.47817 -7.80681  19.39789  1.000 8.64484  ? 26  ILE D N   1 
ATOM   2994 C CA  . ILE E  1 28 ? -26.16016 -6.66032  18.55648  1.000 7.53181  ? 26  ILE D CA  1 
ATOM   2995 C C   . ILE E  1 28 ? -25.14076 -5.78704  19.27449  1.000 7.90621  ? 26  ILE D C   1 
ATOM   2996 O O   . ILE E  1 28 ? -25.33606 -5.41035  20.43731  1.000 9.26565  ? 26  ILE D O   1 
ATOM   2997 C CB  . ILE E  1 28 ? -27.41035 -5.84765  18.18448  1.000 8.19219  ? 26  ILE D CB  1 
ATOM   2998 C CG1 . ILE E  1 28 ? -28.44391 -6.72007  17.47029  1.000 9.89739  ? 26  ILE D CG1 1 
ATOM   2999 C CG2 . ILE E  1 28 ? -27.01333 -4.66132  17.31425  1.000 8.61178  ? 26  ILE D CG2 1 
ATOM   3000 C CD1 . ILE E  1 28 ? -29.82403 -6.08819  17.42919  1.000 10.66398 ? 26  ILE D CD1 1 
ATOM   3001 N N   . THR E  1 29 ? -24.05972 -5.45648  18.57403  1.000 7.83370  ? 27  THR D N   1 
ATOM   3002 C CA  . THR E  1 29 ? -23.02166 -4.55996  19.05605  1.000 7.99577  ? 27  THR D CA  1 
ATOM   3003 C C   . THR E  1 29 ? -22.80373 -3.45461  18.02766  1.000 7.11196  ? 27  THR D C   1 
ATOM   3004 O O   . THR E  1 29 ? -23.36454 -3.48324  16.92697  1.000 7.94023  ? 27  THR D O   1 
ATOM   3005 C CB  . THR E  1 29 ? -21.72206 -5.33001  19.33783  1.000 9.29030  ? 27  THR D CB  1 
ATOM   3006 O OG1 . THR E  1 29 ? -21.34239 -6.05938  18.16692  1.000 10.53912 ? 27  THR D OG1 1 
ATOM   3007 C CG2 . THR E  1 29 ? -21.91502 -6.30472  20.50673  1.000 10.86549 ? 27  THR D CG2 1 
ATOM   3008 N N   . GLU E  1 30 ? -21.97898 -2.47130  18.39241  1.000 6.99243  ? 28  GLU D N   1 
ATOM   3009 C CA  . GLU E  1 30 ? -21.89375 -1.22542  17.64657  1.000 6.64288  ? 28  GLU D CA  1 
ATOM   3010 C C   . GLU E  1 30 ? -20.44048 -0.82549  17.46165  1.000 6.32575  ? 28  GLU D C   1 
ATOM   3011 O O   . GLU E  1 30 ? -19.64295 -0.88494  18.40548  1.000 6.88894  ? 28  GLU D O   1 
ATOM   3012 C CB  . GLU E  1 30 ? -22.62428 -0.13602  18.43682  1.000 7.10937  ? 28  GLU D CB  1 
ATOM   3013 C CG  . GLU E  1 30 ? -22.60788 1.24837   17.83379  1.000 7.18890  ? 28  GLU D CG  1 
ATOM   3014 C CD  . GLU E  1 30 ? -23.11498 2.29840   18.81426  1.000 7.44959  ? 28  GLU D CD  1 
ATOM   3015 O OE1 . GLU E  1 30 ? -22.73161 2.23429   20.00685  1.000 7.67714  ? 28  GLU D OE1 1 
ATOM   3016 O OE2 . GLU E  1 30 ? -23.89577 3.18223   18.39725  1.000 8.07066  ? 28  GLU D OE2 1 
ATOM   3017 N N   . ARG E  1 31 ? -20.10760 -0.40142  16.24345  1.000 6.41759  ? 29  ARG D N   1 
ATOM   3018 C CA  . ARG E  1 31 ? -18.81497 0.19053   15.93138  1.000 7.00003  ? 29  ARG D CA  1 
ATOM   3019 C C   . ARG E  1 31 ? -19.04587 1.62358   15.46904  1.000 6.52462  ? 29  ARG D C   1 
ATOM   3020 O O   . ARG E  1 31 ? -20.04478 1.91638   14.79502  1.000 7.05385  ? 29  ARG D O   1 
ATOM   3021 C CB  . ARG E  1 31 ? -18.05476 -0.63053  14.87549  1.000 7.81386  ? 29  ARG D CB  1 
ATOM   3022 C CG  . ARG E  1 31 ? -17.66944 -2.01338  15.38894  1.000 7.60277  ? 29  ARG D CG  1 
ATOM   3023 C CD  . ARG E  1 31 ? -16.45475 -1.97689  16.31534  1.000 7.87000  ? 29  ARG D CD  1 
ATOM   3024 N NE  . ARG E  1 31 ? -15.21704 -1.82629  15.55529  1.000 7.88938  ? 29  ARG D NE  1 
ATOM   3025 C CZ  . ARG E  1 31 ? -14.01831 -1.65158  16.09628  1.000 8.73275  ? 29  ARG D CZ  1 
ATOM   3026 N NH1 . ARG E  1 31 ? -13.86498 -1.49339  17.40265  1.000 9.89696  ? 29  ARG D NH1 1 
ATOM   3027 N NH2 . ARG E  1 31 ? -12.94549 -1.63513  15.30703  1.000 9.25309  ? 29  ARG D NH2 1 
ATOM   3028 N N   . CYS E  1 32 ? -18.11672 2.51041   15.83025  1.000 6.65367  ? 30  CYS D N   1 
ATOM   3029 C CA  . CYS E  1 32 ? -18.28401 3.95038   15.69630  1.000 6.29356  ? 30  CYS D CA  1 
ATOM   3030 C C   . CYS E  1 32 ? -17.09857 4.55633   14.96479  1.000 6.41653  ? 30  CYS D C   1 
ATOM   3031 O O   . CYS E  1 32 ? -15.94512 4.19114   15.22241  1.000 7.02352  ? 30  CYS D O   1 
ATOM   3032 C CB  . CYS E  1 32 ? -18.33347 4.61813   17.07166  1.000 7.04286  ? 30  CYS D CB  1 
ATOM   3033 S SG  . CYS E  1 32 ? -19.48809 3.87971   18.23658  1.000 7.61379  ? 30  CYS D SG  1 
ATOM   3034 N N   . TRP E  1 33 ? -17.38636 5.52275   14.09347  1.000 6.70670  ? 31  TRP D N   1 
ATOM   3035 C CA  . TRP E  1 33 ? -16.38680 6.33770   13.41643  1.000 7.34371  ? 31  TRP D CA  1 
ATOM   3036 C C   . TRP E  1 33 ? -16.78503 7.79090   13.60159  1.000 7.47422  ? 31  TRP D C   1 
ATOM   3037 O O   . TRP E  1 33 ? -17.92982 8.16088   13.31739  1.000 8.14648  ? 31  TRP D O   1 
ATOM   3038 C CB  . TRP E  1 33 ? -16.37043 6.01607   11.91485  1.000 8.07975  ? 31  TRP D CB  1 
ATOM   3039 C CG  . TRP E  1 33 ? -15.50948 6.92949   11.08209  1.000 8.44104  ? 31  TRP D CG  1 
ATOM   3040 C CD1 . TRP E  1 33 ? -15.87355 8.10225   10.46356  1.000 9.27970  ? 31  TRP D CD1 1 
ATOM   3041 C CD2 . TRP E  1 33 ? -14.13657 6.72117   10.76189  1.000 7.80064  ? 31  TRP D CD2 1 
ATOM   3042 N NE1 . TRP E  1 33 ? -14.79927 8.62979   9.78372   1.000 9.16687  ? 31  TRP D NE1 1 
ATOM   3043 C CE2 . TRP E  1 33 ? -13.72050 7.79975   9.94970   1.000 8.64759  ? 31  TRP D CE2 1 
ATOM   3044 C CE3 . TRP E  1 33 ? -13.21628 5.72142   11.07596  1.000 9.45761  ? 31  TRP D CE3 1 
ATOM   3045 C CZ2 . TRP E  1 33 ? -12.42177 7.90735   9.46025   1.000 8.83032  ? 31  TRP D CZ2 1 
ATOM   3046 C CZ3 . TRP E  1 33 ? -11.93465 5.82917   10.57992  1.000 8.94016  ? 31  TRP D CZ3 1 
ATOM   3047 C CH2 . TRP E  1 33 ? -11.54794 6.90933   9.78330   1.000 10.39212 ? 31  TRP D CH2 1 
ATOM   3048 N N   . ASP E  1 34 ? -15.84988 8.61499   14.08921  1.000 7.56050  ? 32  ASP D N   1 
ATOM   3049 C CA  . ASP E  1 34 ? -16.04471 10.05636  14.18933  1.000 9.13014  ? 32  ASP D CA  1 
ATOM   3050 C C   . ASP E  1 34 ? -14.90390 10.79517  13.50171  1.000 10.37518 ? 32  ASP D C   1 
ATOM   3051 O O   . ASP E  1 34 ? -14.54436 11.90571  13.90902  1.000 12.74918 ? 32  ASP D O   1 
ATOM   3052 C CB  . ASP E  1 34 ? -16.16598 10.53637  15.63923  1.000 10.88915 ? 32  ASP D CB  1 
ATOM   3053 C CG  . ASP E  1 34 ? -17.32153 9.89586   16.40214  1.000 11.57856 ? 32  ASP D CG  1 
ATOM   3054 O OD1 . ASP E  1 34 ? -18.45891 9.80255   15.89397  1.000 11.40764 ? 32  ASP D OD1 1 
ATOM   3055 O OD2 . ASP E  1 34 ? -17.08784 9.51105   17.56717  1.000 18.19110 ? 32  ASP D OD2 1 
ATOM   3056 N N   . GLY E  1 35 ? -14.30392 10.18465  12.48465  1.000 10.02812 ? 33  GLY D N   1 
ATOM   3057 C CA  . GLY E  1 35 ? -13.27492 10.82697  11.69696  1.000 11.76479 ? 33  GLY D CA  1 
ATOM   3058 C C   . GLY E  1 35 ? -11.85313 10.42016  12.02069  1.000 10.77987 ? 33  GLY D C   1 
ATOM   3059 O O   . GLY E  1 35 ? -10.93875 10.80830  11.27954  1.000 13.96134 ? 33  GLY D O   1 
ATOM   3060 N N   . LYS E  1 36 ? -11.63222 9.64096   13.08353  1.000 10.37005 ? 34  LYS D N   1 
ATOM   3061 C CA  . LYS E  1 36 ? -10.28513 9.39576   13.60028  1.000 12.11596 ? 34  LYS D CA  1 
ATOM   3062 C C   . LYS E  1 36 ? -10.10411 7.95034   14.05650  1.000 11.43105 ? 34  LYS D C   1 
ATOM   3063 O O   . LYS E  1 36 ? -9.43471  7.68567   15.06018  1.000 12.93908 ? 34  LYS D O   1 
ATOM   3064 C CB  . LYS E  1 36 ? -9.94181  10.34090  14.75833  1.000 16.88496 ? 34  LYS D CB  1 
ATOM   3065 C CG  . LYS E  1 36 ? -10.62800 11.70063  14.74801  1.000 33.06837 ? 34  LYS D CG  1 
ATOM   3066 C CD  . LYS E  1 36 ? -10.27241 12.50368  15.99746  1.000 38.24162 ? 34  LYS D CD  1 
ATOM   3067 C CE  . LYS E  1 36 ? -10.75544 11.82379  17.27799  1.000 38.92239 ? 34  LYS D CE  1 
ATOM   3068 N NZ  . LYS E  1 36 ? -12.13635 12.22986  17.67160  1.000 32.62791 ? 34  LYS D NZ  1 
ATOM   3069 N N   . GLY E  1 37 ? -10.68009 7.00048   13.34041  1.000 10.26996 ? 35  GLY D N   1 
ATOM   3070 C CA  . GLY E  1 37 ? -10.53423 5.59410   13.66334  1.000 8.55391  ? 35  GLY D CA  1 
ATOM   3071 C C   . GLY E  1 37 ? -11.83095 4.98694   14.18533  1.000 8.30202  ? 35  GLY D C   1 
ATOM   3072 O O   . GLY E  1 37 ? -12.66467 5.66366   14.80673  1.000 9.54361  ? 35  GLY D O   1 
ATOM   3073 N N   . TRP E  1 38 ? -11.99248 3.68868   13.95026  1.000 7.59303  ? 36  TRP D N   1 
ATOM   3074 C CA  . TRP E  1 38 ? -13.15973 2.96195   14.43242  1.000 7.56698  ? 36  TRP D CA  1 
ATOM   3075 C C   . TRP E  1 38 ? -12.93929 2.49349   15.86585  1.000 7.49132  ? 36  TRP D C   1 
ATOM   3076 O O   . TRP E  1 38 ? -11.83056 2.08689   16.24066  1.000 8.62853  ? 36  TRP D O   1 
ATOM   3077 C CB  . TRP E  1 38 ? -13.41242 1.74588   13.54213  1.000 8.01090  ? 36  TRP D CB  1 
ATOM   3078 C CG  . TRP E  1 38 ? -13.94340 2.10959   12.19937  1.000 6.59508  ? 36  TRP D CG  1 
ATOM   3079 C CD1 . TRP E  1 38 ? -13.22167 2.35153   11.06618  1.000 6.65869  ? 36  TRP D CD1 1 
ATOM   3080 C CD2 . TRP E  1 38 ? -15.31459 2.30400   11.85505  1.000 6.34342  ? 36  TRP D CD2 1 
ATOM   3081 N NE1 . TRP E  1 38 ? -14.06396 2.68369   10.03225  1.000 7.35386  ? 36  TRP D NE1 1 
ATOM   3082 C CE2 . TRP E  1 38 ? -15.35614 2.66256   10.49063  1.000 6.33147  ? 36  TRP D CE2 1 
ATOM   3083 C CE3 . TRP E  1 38 ? -16.51811 2.21138   12.56844  1.000 6.57791  ? 36  TRP D CE3 1 
ATOM   3084 C CZ2 . TRP E  1 38 ? -16.55298 2.92466   9.81996   1.000 7.11661  ? 36  TRP D CZ2 1 
ATOM   3085 C CZ3 . TRP E  1 38 ? -17.70606 2.46139   11.90080  1.000 6.53903  ? 36  TRP D CZ3 1 
ATOM   3086 C CH2 . TRP E  1 38 ? -17.71358 2.82215   10.54328  1.000 6.78433  ? 36  TRP D CH2 1 
ATOM   3087 N N   . TYR E  1 39 ? -14.00431 2.54138   16.66632  1.000 7.53913  ? 37  TYR D N   1 
ATOM   3088 C CA  . TYR E  1 39 ? -13.95452 2.09343   18.05222  1.000 7.27184  ? 37  TYR D CA  1 
ATOM   3089 C C   . TYR E  1 39 ? -15.31452 1.52096   18.44334  1.000 6.90032  ? 37  TYR D C   1 
ATOM   3090 O O   . TYR E  1 39 ? -16.32584 1.73189   17.76270  1.000 8.06733  ? 37  TYR D O   1 
ATOM   3091 C CB  . TYR E  1 39 ? -13.52194 3.23434   18.98552  1.000 8.71028  ? 37  TYR D CB  1 
ATOM   3092 C CG  . TYR E  1 39 ? -14.48708 4.39594   19.00067  1.000 7.97017  ? 37  TYR D CG  1 
ATOM   3093 C CD1 . TYR E  1 39 ? -14.39399 5.42038   18.06732  1.000 9.40255  ? 37  TYR D CD1 1 
ATOM   3094 C CD2 . TYR E  1 39 ? -15.50081 4.45996   19.94382  1.000 9.17441  ? 37  TYR D CD2 1 
ATOM   3095 C CE1 . TYR E  1 39 ? -15.28298 6.47959   18.08087  1.000 9.67246  ? 37  TYR D CE1 1 
ATOM   3096 C CE2 . TYR E  1 39 ? -16.39117 5.50639   19.96692  1.000 9.99833  ? 37  TYR D CE2 1 
ATOM   3097 C CZ  . TYR E  1 39 ? -16.28298 6.51374   19.03574  1.000 10.15342 ? 37  TYR D CZ  1 
ATOM   3098 O OH  . TYR E  1 39 ? -17.18936 7.55172   19.07717  1.000 12.73786 ? 37  TYR D OH  1 
ATOM   3099 N N   . THR E  1 40 ? -15.34432 0.79506   19.55227  1.000 7.52720  ? 38  THR D N   1 
ATOM   3100 C CA  . THR E  1 40 ? -16.55536 0.09967   19.95591  1.000 8.42636  ? 38  THR D CA  1 
ATOM   3101 C C   . THR E  1 40 ? -17.46587 1.02458   20.75579  1.000 6.83946  ? 38  THR D C   1 
ATOM   3102 O O   . THR E  1 40 ? -17.01117 1.74067   21.65455  1.000 7.90763  ? 38  THR D O   1 
ATOM   3103 C CB  . THR E  1 40 ? -16.18809 -1.16733  20.72202  1.000 8.25747  ? 38  THR D CB  1 
ATOM   3104 O OG1 . THR E  1 40 ? -15.56244 -2.06714  19.79371  1.000 9.42664  ? 38  THR D OG1 1 
ATOM   3105 C CG2 . THR E  1 40 ? -17.41386 -1.83001  21.33240  1.000 9.95456  ? 38  THR D CG2 1 
ATOM   3106 N N   . GLY E  1 41 ? -18.75888 1.02926   20.39980  1.000 6.93469  ? 39  GLY D N   1 
ATOM   3107 C CA  . GLY E  1 41 ? -19.72833 1.86474   21.07124  1.000 8.68970  ? 39  GLY D CA  1 
ATOM   3108 C C   . GLY E  1 41 ? -20.40298 1.18231   22.24815  1.000 7.34905  ? 39  GLY D C   1 
ATOM   3109 O O   . GLY E  1 41 ? -20.21347 -0.00161  22.52625  1.000 8.13867  ? 39  GLY D O   1 
ATOM   3110 N N   . ALA E  1 42 ? -21.22762 1.96743   22.94629  1.000 7.79377  ? 40  ALA D N   1 
ATOM   3111 C CA  . ALA E  1 42 ? -21.90633 1.46862   24.13171  1.000 8.78065  ? 40  ALA D CA  1 
ATOM   3112 C C   . ALA E  1 42 ? -23.09218 0.56600   23.82125  1.000 7.27302  ? 40  ALA D C   1 
ATOM   3113 O O   . ALA E  1 42 ? -23.55020 -0.14654  24.72195  1.000 9.60920  ? 40  ALA D O   1 
ATOM   3114 C CB  . ALA E  1 42 ? -22.38136 2.63065   25.00328  1.000 10.47496 ? 40  ALA D CB  1 
ATOM   3115 N N   . PHE E  1 43 ? -23.60599 0.56642   22.59238  1.000 8.22066  ? 41  PHE D N   1 
ATOM   3116 C CA  . PHE E  1 43 ? -24.81650 -0.19856  22.30796  1.000 8.03361  ? 41  PHE D CA  1 
ATOM   3117 C C   . PHE E  1 43 ? -24.55321 -1.69656  22.44809  1.000 8.57775  ? 41  PHE D C   1 
ATOM   3118 O O   . PHE E  1 43 ? -23.67280 -2.24214  21.77551  1.000 8.95200  ? 41  PHE D O   1 
ATOM   3119 C CB  . PHE E  1 43 ? -25.33902 0.10269   20.90642  1.000 8.73608  ? 41  PHE D CB  1 
ATOM   3120 C CG  . PHE E  1 43 ? -26.65219 -0.57181  20.60818  1.000 8.29230  ? 41  PHE D CG  1 
ATOM   3121 C CD1 . PHE E  1 43 ? -26.71450 -1.87677  20.13871  1.000 9.67239  ? 41  PHE D CD1 1 
ATOM   3122 C CD2 . PHE E  1 43 ? -27.83590 0.09996   20.81122  1.000 10.91131 ? 41  PHE D CD2 1 
ATOM   3123 C CE1 . PHE E  1 43 ? -27.93332 -2.48898  19.88830  1.000 9.45644  ? 41  PHE D CE1 1 
ATOM   3124 C CE2 . PHE E  1 43 ? -29.05651 -0.50952  20.54916  1.000 11.54302 ? 41  PHE D CE2 1 
ATOM   3125 C CZ  . PHE E  1 43 ? -29.09823 -1.80977  20.10725  1.000 10.47137 ? 41  PHE D CZ  1 
ATOM   3126 N N   . ASN E  1 44 ? -25.35104 -2.36889  23.28111  1.000 9.27709  ? 42  ASN D N   1 
ATOM   3127 C CA  . ASN E  1 44 ? -25.22682 -3.81378  23.49054  1.000 10.48837 ? 42  ASN D CA  1 
ATOM   3128 C C   . ASN E  1 44 ? -26.62717 -4.31408  23.83818  1.000 10.35548 ? 42  ASN D C   1 
ATOM   3129 O O   . ASN E  1 44 ? -27.05850 -4.14951  24.98048  1.000 11.94708 ? 42  ASN D O   1 
ATOM   3130 C CB  . ASN E  1 44 ? -24.28393 -4.09927  24.65624  1.000 14.15660 ? 42  ASN D CB  1 
ATOM   3131 C CG  . ASN E  1 44 ? -22.81984 -3.91921  24.31185  1.000 17.81702 ? 42  ASN D CG  1 
ATOM   3132 O OD1 . ASN E  1 44 ? -22.19371 -4.80719  23.72860  1.000 20.20883 ? 42  ASN D OD1 1 
ATOM   3133 N ND2 . ASN E  1 44 ? -22.24890 -2.78839  24.72172  1.000 19.28788 ? 42  ASN D ND2 1 
ATOM   3134 N N   . GLU E  1 45 ? -27.33218 -4.91304  22.88009  1.000 9.50318  ? 43  GLU D N   1 
ATOM   3135 C CA  . GLU E  1 45 ? -28.68281 -5.40072  23.14651  1.000 9.44607  ? 43  GLU D CA  1 
ATOM   3136 C C   . GLU E  1 45 ? -28.93237 -6.68143  22.36856  1.000 8.98658  ? 43  GLU D C   1 
ATOM   3137 O O   . GLU E  1 45 ? -28.32459 -6.89375  21.31385  1.000 9.83397  ? 43  GLU D O   1 
ATOM   3138 C CB  . GLU E  1 45 ? -29.76166 -4.37698  22.75247  1.000 11.87191 ? 43  GLU D CB  1 
ATOM   3139 C CG  . GLU E  1 45 ? -29.63077 -3.01536  23.39712  1.000 13.90516 ? 43  GLU D CG  1 
ATOM   3140 C CD  . GLU E  1 45 ? -29.89223 -3.02985  24.88749  1.000 13.25284 ? 43  GLU D CD  1 
ATOM   3141 O OE1 . GLU E  1 45 ? -30.36996 -4.05982  25.41662  1.000 14.66030 ? 43  GLU D OE1 1 
ATOM   3142 O OE2 . GLU E  1 45 ? -29.61231 -2.00059  25.53326  1.000 15.05711 ? 43  GLU D OE2 1 
ATOM   3143 N N   . PRO E  1 46 ? -29.84522 -7.53241  22.83957  1.000 9.68832  ? 44  PRO D N   1 
ATOM   3144 C CA  . PRO E  1 46 ? -30.13810 -8.77178  22.11250  1.000 10.81358 ? 44  PRO D CA  1 
ATOM   3145 C C   . PRO E  1 46 ? -30.84354 -8.50094  20.79380  1.000 10.87269 ? 44  PRO D C   1 
ATOM   3146 O O   . PRO E  1 46 ? -31.62918 -7.55866  20.65913  1.000 10.85058 ? 44  PRO D O   1 
ATOM   3147 C CB  . PRO E  1 46 ? -31.07001 -9.53565  23.06155  1.000 13.58981 ? 44  PRO D CB  1 
ATOM   3148 C CG  . PRO E  1 46 ? -30.90275 -8.89810  24.38956  1.000 14.55998 ? 44  PRO D CG  1 
ATOM   3149 C CD  . PRO E  1 46 ? -30.53948 -7.47044  24.13756  1.000 10.43695 ? 44  PRO D CD  1 
ATOM   3150 N N   . GLY E  1 47 ? -30.57245 -9.36456  19.82244  1.000 10.22406 ? 45  GLY D N   1 
ATOM   3151 C CA  . GLY E  1 47 ? -31.27715 -9.31323  18.55932  1.000 10.85664 ? 45  GLY D CA  1 
ATOM   3152 C C   . GLY E  1 47 ? -30.63738 -10.18134 17.50031  1.000 10.33610 ? 45  GLY D C   1 
ATOM   3153 O O   . GLY E  1 47 ? -29.41647 -10.38121 17.49292  1.000 10.34517 ? 45  GLY D O   1 
ATOM   3154 N N   . ASP E  1 48 ? -31.46787 -10.71300 16.60331  1.000 9.38499  ? 46  ASP D N   1 
ATOM   3155 C CA  . ASP E  1 48 ? -31.01004 -11.45188 15.43267  1.000 10.35162 ? 46  ASP D CA  1 
ATOM   3156 C C   . ASP E  1 48 ? -31.02360 -10.61064 14.17281  1.000 10.31182 ? 46  ASP D C   1 
ATOM   3157 O O   . ASP E  1 48 ? -30.25321 -10.87927 13.24818  1.000 12.38323 ? 46  ASP D O   1 
ATOM   3158 C CB  . ASP E  1 48 ? -31.93154 -12.64684 15.17415  1.000 12.60352 ? 46  ASP D CB  1 
ATOM   3159 C CG  . ASP E  1 48 ? -31.87284 -13.67852 16.26913  1.000 16.91841 ? 46  ASP D CG  1 
ATOM   3160 O OD1 . ASP E  1 48 ? -30.75294 -14.00540 16.71575  1.000 19.47933 ? 46  ASP D OD1 1 
ATOM   3161 O OD2 . ASP E  1 48 ? -32.95116 -14.15986 16.67720  1.000 23.33786 ? 46  ASP D OD2 1 
ATOM   3162 N N   A ASN E  1 49 ? -31.88428 -9.60141  14.13076  0.579 9.37758  ? 47  ASN D N   1 
ATOM   3163 N N   B ASN E  1 49 ? -31.90638 -9.62308  14.08805  0.421 9.35704  ? 47  ASN D N   1 
ATOM   3164 C CA  A ASN E  1 49 ? -32.03364 -8.70725  12.99941  0.579 8.63442  ? 47  ASN D CA  1 
ATOM   3165 C CA  B ASN E  1 49 ? -31.96569 -8.72368  12.94848  0.421 8.62244  ? 47  ASN D CA  1 
ATOM   3166 C C   A ASN E  1 49 ? -31.97120 -7.28297  13.52072  0.579 7.24493  ? 47  ASN D C   1 
ATOM   3167 C C   B ASN E  1 49 ? -32.03179 -7.29417  13.46495  0.421 7.41017  ? 47  ASN D C   1 
ATOM   3168 O O   A ASN E  1 49 ? -32.37673 -7.01202  14.65105  0.579 8.41131  ? 47  ASN D O   1 
ATOM   3169 O O   B ASN E  1 49 ? -32.57930 -7.03339  14.53696  0.421 7.60911  ? 47  ASN D O   1 
ATOM   3170 C CB  A ASN E  1 49 ? -33.39332 -8.93778  12.33434  0.579 10.54793 ? 47  ASN D CB  1 
ATOM   3171 C CB  B ASN E  1 49 ? -33.16911 -9.03629  12.03298  0.421 9.04110  ? 47  ASN D CB  1 
ATOM   3172 C CG  A ASN E  1 49 ? -33.70013 -7.90980  11.27382  0.579 9.71057  ? 47  ASN D CG  1 
ATOM   3173 C CG  B ASN E  1 49 ? -32.99330 -10.33128 11.24201  0.421 11.84028 ? 47  ASN D CG  1 
ATOM   3174 O OD1 A ASN E  1 49 ? -34.41843 -6.93600  11.51320  0.579 9.70342  ? 47  ASN D OD1 1 
ATOM   3175 O OD1 B ASN E  1 49 ? -31.91979 -10.60410 10.68956  0.421 10.91235 ? 47  ASN D OD1 1 
ATOM   3176 N ND2 A ASN E  1 49 ? -33.14382 -8.11395  10.09001  0.579 13.07195 ? 47  ASN D ND2 1 
ATOM   3177 N ND2 B ASN E  1 49 ? -34.05516 -11.13170 11.17834  0.421 14.66735 ? 47  ASN D ND2 1 
ATOM   3178 N N   . VAL E  1 50 ? -31.45919 -6.37076  12.69961  1.000 7.34807  ? 48  VAL D N   1 
ATOM   3179 C CA  . VAL E  1 50 ? -31.29954 -4.98988  13.13162  1.000 6.56817  ? 48  VAL D CA  1 
ATOM   3180 C C   . VAL E  1 50 ? -31.55172 -4.02960  11.97749  1.000 6.79615  ? 48  VAL D C   1 
ATOM   3181 O O   . VAL E  1 50 ? -31.14733 -4.27995  10.83740  1.000 7.72084  ? 48  VAL D O   1 
ATOM   3182 C CB  . VAL E  1 50 ? -29.91838 -4.77209  13.80001  1.000 7.86085  ? 48  VAL D CB  1 
ATOM   3183 C CG1 . VAL E  1 50 ? -28.76890 -5.03271  12.82550  1.000 9.65345  ? 48  VAL D CG1 1 
ATOM   3184 C CG2 . VAL E  1 50 ? -29.82118 -3.38447  14.39582  1.000 9.75329  ? 48  VAL D CG2 1 
ATOM   3185 N N   . SER E  1 51 ? -32.24364 -2.93573  12.28218  1.000 6.91696  ? 49  SER D N   1 
ATOM   3186 C CA  . SER E  1 51 ? -32.31346 -1.78269  11.40372  1.000 6.35925  ? 49  SER D CA  1 
ATOM   3187 C C   . SER E  1 51 ? -32.09026 -0.53422  12.24252  1.000 6.16503  ? 49  SER D C   1 
ATOM   3188 O O   . SER E  1 51 ? -32.14494 -0.57761  13.47419  1.000 6.69642  ? 49  SER D O   1 
ATOM   3189 C CB  . SER E  1 51 ? -33.64494 -1.69764  10.64107  1.000 7.02659  ? 49  SER D CB  1 
ATOM   3190 O OG  . SER E  1 51 ? -34.73201 -1.40158  11.49360  1.000 7.72880  ? 49  SER D OG  1 
ATOM   3191 N N   . VAL E  1 52 ? -31.84275 0.59179   11.57533  1.000 6.33363  ? 50  VAL D N   1 
ATOM   3192 C CA  . VAL E  1 52 ? -31.50892 1.82315   12.28151  1.000 6.35961  ? 50  VAL D CA  1 
ATOM   3193 C C   . VAL E  1 52 ? -31.95650 3.02219   11.45961  1.000 6.33138  ? 50  VAL D C   1 
ATOM   3194 O O   . VAL E  1 52 ? -31.96641 2.98570   10.22714  1.000 7.26052  ? 50  VAL D O   1 
ATOM   3195 C CB  . VAL E  1 52 ? -29.98962 1.90488   12.60379  1.000 6.54855  ? 50  VAL D CB  1 
ATOM   3196 C CG1 . VAL E  1 52 ? -29.15475 1.98544   11.33184  1.000 7.18984  ? 50  VAL D CG1 1 
ATOM   3197 C CG2 . VAL E  1 52 ? -29.67781 3.08474   13.52730  1.000 7.72715  ? 50  VAL D CG2 1 
ATOM   3198 N N   . THR E  1 53 ? -32.31175 4.09641   12.15642  1.000 6.51407  ? 51  THR D N   1 
ATOM   3199 C CA  . THR E  1 53 ? -32.45791 5.40920   11.55320  1.000 6.38362  ? 51  THR D CA  1 
ATOM   3200 C C   . THR E  1 53 ? -31.94668 6.43182   12.55566  1.000 6.56492  ? 51  THR D C   1 
ATOM   3201 O O   . THR E  1 53 ? -31.80982 6.13065   13.74058  1.000 7.99764  ? 51  THR D O   1 
ATOM   3202 C CB  . THR E  1 53 ? -33.90832 5.67102   11.11255  1.000 7.55697  ? 51  THR D CB  1 
ATOM   3203 O OG1 . THR E  1 53 ? -33.95795 6.84428   10.29835  1.000 8.04946  ? 51  THR D OG1 1 
ATOM   3204 C CG2 . THR E  1 53 ? -34.83480 5.83702   12.31800  1.000 8.29479  ? 51  THR D CG2 1 
ATOM   3205 N N   . SER E  1 54 ? -31.60244 7.62539   12.07152  1.000 7.02175  ? 52  SER D N   1 
ATOM   3206 C CA  . SER E  1 54 ? -31.12363 8.67241   12.96429  1.000 7.80347  ? 52  SER D CA  1 
ATOM   3207 C C   . SER E  1 54 ? -31.45027 10.03651  12.37168  1.000 7.76289  ? 52  SER D C   1 
ATOM   3208 O O   . SER E  1 54 ? -31.67565 10.17354  11.16881  1.000 8.54937  ? 52  SER D O   1 
ATOM   3209 C CB  . SER E  1 54 ? -29.61781 8.54497   13.24985  1.000 7.75818  ? 52  SER D CB  1 
ATOM   3210 O OG  . SER E  1 54 ? -28.84704 8.85711   12.10379  1.000 7.81054  ? 52  SER D OG  1 
ATOM   3211 N N   . TRP E  1 55 ? -31.46958 11.05015  13.23338  1.000 8.55726  ? 53  TRP D N   1 
ATOM   3212 C CA  . TRP E  1 55 ? -31.70065 12.41704  12.79084  1.000 9.05699  ? 53  TRP D CA  1 
ATOM   3213 C C   . TRP E  1 55 ? -30.86849 13.36223  13.64344  1.000 10.84249 ? 53  TRP D C   1 
ATOM   3214 O O   . TRP E  1 55 ? -30.71312 13.15572  14.84771  1.000 10.07314 ? 53  TRP D O   1 
ATOM   3215 C CB  . TRP E  1 55 ? -33.19449 12.80743  12.79412  1.000 12.09898 ? 53  TRP D CB  1 
ATOM   3216 C CG  . TRP E  1 55 ? -33.86040 12.73529  14.12931  1.000 10.50547 ? 53  TRP D CG  1 
ATOM   3217 C CD1 . TRP E  1 55 ? -34.05944 13.76616  15.00141  1.000 12.86873 ? 53  TRP D CD1 1 
ATOM   3218 C CD2 . TRP E  1 55 ? -34.42730 11.57458  14.74148  1.000 9.39354  ? 53  TRP D CD2 1 
ATOM   3219 N NE1 . TRP E  1 55 ? -34.70894 13.31485  16.12359  1.000 11.28728 ? 53  TRP D NE1 1 
ATOM   3220 C CE2 . TRP E  1 55 ? -34.94906 11.97227  15.98846  1.000 10.26801 ? 53  TRP D CE2 1 
ATOM   3221 C CE3 . TRP E  1 55 ? -34.54968 10.23443  14.35676  1.000 9.92206  ? 53  TRP D CE3 1 
ATOM   3222 C CZ2 . TRP E  1 55 ? -35.56532 11.07523  16.86195  1.000 10.18832 ? 53  TRP D CZ2 1 
ATOM   3223 C CZ3 . TRP E  1 55 ? -35.17569 9.34888   15.22180  1.000 9.39718  ? 53  TRP D CZ3 1 
ATOM   3224 C CH2 . TRP E  1 55 ? -35.67583 9.77100   16.45643  1.000 9.93483  ? 53  TRP D CH2 1 
ATOM   3225 N N   . LEU E  1 56 ? -30.30221 14.37845  12.99105  1.000 16.40218 ? 54  LEU D N   1 
ATOM   3226 C CA  . LEU E  1 56 ? -29.36036 15.32225  13.59264  1.000 20.28049 ? 54  LEU D CA  1 
ATOM   3227 C C   . LEU E  1 56 ? -30.03243 16.68383  13.57565  1.000 21.97830 ? 54  LEU D C   1 
ATOM   3228 O O   . LEU E  1 56 ? -30.29352 17.23333  12.50083  1.000 19.70317 ? 54  LEU D O   1 
ATOM   3229 C CB  . LEU E  1 56 ? -28.05697 15.38137  12.78903  1.000 14.12346 ? 54  LEU D CB  1 
ATOM   3230 C CG  . LEU E  1 56 ? -26.95497 16.31585  13.29403  1.000 20.82045 ? 54  LEU D CG  1 
ATOM   3231 C CD1 . LEU E  1 56 ? -26.42579 15.83963  14.63494  1.000 17.96335 ? 54  LEU D CD1 1 
ATOM   3232 C CD2 . LEU E  1 56 ? -25.82385 16.42913  12.27463  1.000 22.45314 ? 54  LEU D CD2 1 
ATOM   3233 N N   . VAL E  1 57 ? -30.32259 17.22270  14.75710  1.000 26.33629 ? 55  VAL D N   1 
ATOM   3234 C CA  . VAL E  1 57 ? -30.99283 18.51144  14.88608  1.000 29.25862 ? 55  VAL D CA  1 
ATOM   3235 C C   . VAL E  1 57 ? -30.20830 19.36343  15.87758  1.000 23.09585 ? 55  VAL D C   1 
ATOM   3236 O O   . VAL E  1 57 ? -29.97728 18.94540  17.01932  1.000 17.62682 ? 55  VAL D O   1 
ATOM   3237 C CB  . VAL E  1 57 ? -32.46050 18.35910  15.32144  1.000 28.95206 ? 55  VAL D CB  1 
ATOM   3238 C CG1 . VAL E  1 57 ? -33.19392 19.67033  15.15564  1.000 32.19259 ? 55  VAL D CG1 1 
ATOM   3239 C CG2 . VAL E  1 57 ? -33.15071 17.27294  14.50576  1.000 33.99620 ? 55  VAL D CG2 1 
ATOM   3240 N N   . GLY E  1 58 ? -29.78599 20.54466  15.43910  1.000 20.10869 ? 56  GLY D N   1 
ATOM   3241 C CA  . GLY E  1 58 ? -28.99351 21.40853  16.30140  1.000 26.73967 ? 56  GLY D CA  1 
ATOM   3242 C C   . GLY E  1 58 ? -27.69478 20.78012  16.75797  1.000 22.55234 ? 56  GLY D C   1 
ATOM   3243 O O   . GLY E  1 58 ? -27.26844 20.99662  17.90115  1.000 24.08008 ? 56  GLY D O   1 
ATOM   3244 N N   . SER E  1 59 ? -27.05870 19.99288  15.88789  1.000 17.68207 ? 57  SER D N   1 
ATOM   3245 C CA  . SER E  1 59 ? -25.79790 19.30018  16.14772  1.000 21.13932 ? 57  SER D CA  1 
ATOM   3246 C C   . SER E  1 59 ? -25.90977 18.19745  17.19216  1.000 27.41357 ? 57  SER D C   1 
ATOM   3247 O O   . SER E  1 59 ? -24.88162 17.71905  17.69033  1.000 27.75218 ? 57  SER D O   1 
ATOM   3248 C CB  . SER E  1 59 ? -24.64568 20.25410  16.49036  1.000 22.90744 ? 57  SER D CB  1 
ATOM   3249 O OG  . SER E  1 59 ? -24.42943 21.17641  15.43651  1.000 36.25794 ? 57  SER D OG  1 
ATOM   3250 N N   . ALA E  1 60 ? -27.11961 17.77474  17.54124  1.000 16.54335 ? 58  ALA D N   1 
ATOM   3251 C CA  . ALA E  1 60 ? -27.32371 16.67880  18.47818  1.000 15.72386 ? 58  ALA D CA  1 
ATOM   3252 C C   . ALA E  1 60 ? -27.95280 15.50714  17.73702  1.000 11.41625 ? 58  ALA D C   1 
ATOM   3253 O O   . ALA E  1 60 ? -28.97907 15.67252  17.06954  1.000 12.31135 ? 58  ALA D O   1 
ATOM   3254 C CB  . ALA E  1 60 ? -28.22149 17.11752  19.63676  1.000 17.79323 ? 58  ALA D CB  1 
ATOM   3255 N N   . ILE E  1 61 ? -27.32823 14.32848  17.84499  1.000 12.09723 ? 59  ILE D N   1 
ATOM   3256 C CA  . ILE E  1 61 ? -27.78220 13.13921  17.13129  1.000 10.07416 ? 59  ILE D CA  1 
ATOM   3257 C C   . ILE E  1 61 ? -28.79827 12.38620  17.97887  1.000 8.80684  ? 59  ILE D C   1 
ATOM   3258 O O   . ILE E  1 61 ? -28.68465 12.29995  19.21037  1.000 11.47536 ? 59  ILE D O   1 
ATOM   3259 C CB  . ILE E  1 61 ? -26.59281 12.23849  16.73563  1.000 11.06607 ? 59  ILE D CB  1 
ATOM   3260 C CG1 . ILE E  1 61 ? -27.04395 11.12562  15.78526  1.000 9.54829  ? 59  ILE D CG1 1 
ATOM   3261 C CG2 . ILE E  1 61 ? -25.92273 11.63878  17.96521  1.000 11.68431 ? 59  ILE D CG2 1 
ATOM   3262 C CD1 . ILE E  1 61 ? -27.57745 11.63879  14.46753  1.000 9.96380  ? 59  ILE D CD1 1 
ATOM   3263 N N   . HIS E  1 62 ? -29.80152 11.83663  17.30320  1.000 8.50446  ? 60  HIS D N   1 
ATOM   3264 C CA  . HIS E  1 62 ? -30.79208 10.95485  17.89958  1.000 7.85307  ? 60  HIS D CA  1 
ATOM   3265 C C   . HIS E  1 62 ? -30.81939 9.69774   17.05570  1.000 7.43001  ? 60  HIS D C   1 
ATOM   3266 O O   . HIS E  1 62 ? -30.99482 9.78529   15.84082  1.000 9.14175  ? 60  HIS D O   1 
ATOM   3267 C CB  . HIS E  1 62 ? -32.15210 11.63615  17.88566  1.000 9.51601  ? 60  HIS D CB  1 
ATOM   3268 C CG  . HIS E  1 62 ? -32.15257 12.92211  18.64325  1.000 10.95182 ? 60  HIS D CG  1 
ATOM   3269 N ND1 . HIS E  1 62 ? -32.48995 13.00399  19.97691  1.000 12.85703 ? 60  HIS D ND1 1 
ATOM   3270 C CD2 . HIS E  1 62 ? -31.78465 14.16874  18.26795  1.000 13.21158 ? 60  HIS D CD2 1 
ATOM   3271 C CE1 . HIS E  1 62 ? -32.36517 14.25669  20.38086  1.000 15.87615 ? 60  HIS D CE1 1 
ATOM   3272 N NE2 . HIS E  1 62 ? -31.93898 14.98275  19.36310  1.000 16.93068 ? 60  HIS D NE2 1 
ATOM   3273 N N   . ILE E  1 63 ? -30.61438 8.54331   17.68367  1.000 7.40370  ? 61  ILE D N   1 
ATOM   3274 C CA  . ILE E  1 63 ? -30.51272 7.27423   16.97170  1.000 6.47940  ? 61  ILE D CA  1 
ATOM   3275 C C   . ILE E  1 63 ? -31.61614 6.35860   17.47460  1.000 6.40623  ? 61  ILE D C   1 
ATOM   3276 O O   . ILE E  1 63 ? -31.88468 6.30964   18.68083  1.000 7.03391  ? 61  ILE D O   1 
ATOM   3277 C CB  . ILE E  1 63 ? -29.14385 6.59166   17.18909  1.000 6.71070  ? 61  ILE D CB  1 
ATOM   3278 C CG1 . ILE E  1 63 ? -27.99247 7.58077   16.99710  1.000 8.01752  ? 61  ILE D CG1 1 
ATOM   3279 C CG2 . ILE E  1 63 ? -29.01199 5.39510   16.25713  1.000 8.12633  ? 61  ILE D CG2 1 
ATOM   3280 C CD1 . ILE E  1 63 ? -26.64161 7.04118   17.44756  1.000 8.82076  ? 61  ILE D CD1 1 
ATOM   3281 N N   . ARG E  1 64 ? -32.26539 5.64757   16.55885  1.000 6.69950  ? 62  ARG D N   1 
ATOM   3282 C CA  . ARG E  1 64 ? -33.22120 4.60565   16.90674  1.000 6.13177  ? 62  ARG D CA  1 
ATOM   3283 C C   . ARG E  1 64 ? -32.79108 3.30672   16.23641  1.000 6.89255  ? 62  ARG D C   1 
ATOM   3284 O O   . ARG E  1 64 ? -32.68026 3.24482   15.00463  1.000 6.80376  ? 62  ARG D O   1 
ATOM   3285 C CB  . ARG E  1 64 ? -34.64007 4.98116   16.47133  1.000 6.90683  ? 62  ARG D CB  1 
ATOM   3286 C CG  . ARG E  1 64 ? -35.16360 6.27011   17.09260  1.000 7.26491  ? 62  ARG D CG  1 
ATOM   3287 C CD  . ARG E  1 64 ? -35.32492 6.14868   18.60241  1.000 7.69462  ? 62  ARG D CD  1 
ATOM   3288 N NE  . ARG E  1 64 ? -35.83949 7.37607   19.19752  1.000 7.50272  ? 62  ARG D NE  1 
ATOM   3289 C CZ  . ARG E  1 64 ? -35.08101 8.36721   19.65119  1.000 7.65811  ? 62  ARG D CZ  1 
ATOM   3290 N NH1 . ARG E  1 64 ? -33.75730 8.29373   19.62724  1.000 8.39069  ? 62  ARG D NH1 1 
ATOM   3291 N NH2 . ARG E  1 64 ? -35.66156 9.46225   20.13789  1.000 8.93328  ? 62  ARG D NH2 1 
ATOM   3292 N N   . VAL E  1 65 ? -32.54946 2.28120   17.05023  1.000 6.61366  ? 63  VAL D N   1 
ATOM   3293 C CA  . VAL E  1 65 ? -32.16221 0.95048   16.59563  1.000 6.05323  ? 63  VAL D CA  1 
ATOM   3294 C C   . VAL E  1 65 ? -33.32896 0.01184   16.85587  1.000 6.05896  ? 63  VAL D C   1 
ATOM   3295 O O   . VAL E  1 65 ? -33.85608 -0.02562  17.97321  1.000 7.74404  ? 63  VAL D O   1 
ATOM   3296 C CB  . VAL E  1 65 ? -30.90387 0.45955   17.33118  1.000 6.86231  ? 63  VAL D CB  1 
ATOM   3297 C CG1 . VAL E  1 65 ? -30.57599 -0.95669  16.91800  1.000 9.09798  ? 63  VAL D CG1 1 
ATOM   3298 C CG2 . VAL E  1 65 ? -29.72203 1.38218   17.04184  1.000 7.80693  ? 63  VAL D CG2 1 
ATOM   3299 N N   . TYR E  1 66 ? -33.72378 -0.75064  15.83491  1.000 6.03339  ? 64  TYR D N   1 
ATOM   3300 C CA  . TYR E  1 66 ? -34.83712 -1.70048  15.91457  1.000 6.70298  ? 64  TYR D CA  1 
ATOM   3301 C C   . TYR E  1 66 ? -34.24613 -3.10201  15.91075  1.000 6.55167  ? 64  TYR D C   1 
ATOM   3302 O O   . TYR E  1 66 ? -33.71139 -3.55367  14.89193  1.000 7.33254  ? 64  TYR D O   1 
ATOM   3303 C CB  . TYR E  1 66 ? -35.85223 -1.46510  14.78751  1.000 6.81015  ? 64  TYR D CB  1 
ATOM   3304 C CG  . TYR E  1 66 ? -36.41089 -0.06437  14.91403  1.000 6.24447  ? 64  TYR D CG  1 
ATOM   3305 C CD1 . TYR E  1 66 ? -37.47162 0.20663   15.75856  1.000 7.48848  ? 64  TYR D CD1 1 
ATOM   3306 C CD2 . TYR E  1 66 ? -35.81465 1.00234   14.27178  1.000 7.50778  ? 64  TYR D CD2 1 
ATOM   3307 C CE1 . TYR E  1 66 ? -37.93727 1.49865   15.93227  1.000 7.04919  ? 64  TYR D CE1 1 
ATOM   3308 C CE2 . TYR E  1 66 ? -36.26789 2.29526   14.44870  1.000 6.69002  ? 64  TYR D CE2 1 
ATOM   3309 C CZ  . TYR E  1 66 ? -37.32606 2.53879   15.28327  1.000 6.90441  ? 64  TYR D CZ  1 
ATOM   3310 O OH  . TYR E  1 66 ? -37.74839 3.83976   15.45899  1.000 7.87114  ? 64  TYR D OH  1 
ATOM   3311 N N   . ALA E  1 67 ? -34.31139 -3.76134  17.06482  1.000 7.15276  ? 65  ALA D N   1 
ATOM   3312 C CA  . ALA E  1 67 ? -33.70320 -5.06586  17.29215  1.000 7.17204  ? 65  ALA D CA  1 
ATOM   3313 C C   . ALA E  1 67 ? -34.80418 -6.11407  17.35723  1.000 7.66826  ? 65  ALA D C   1 
ATOM   3314 O O   . ALA E  1 67 ? -35.73596 -5.97334  18.15360  1.000 9.07498  ? 65  ALA D O   1 
ATOM   3315 C CB  . ALA E  1 67 ? -32.95576 -5.06272  18.62762  1.000 9.06450  ? 65  ALA D CB  1 
ATOM   3316 N N   . SER E  1 68 ? -34.70441 -7.16013  16.53927  1.000 7.59946  ? 66  SER D N   1 
ATOM   3317 C CA  . SER E  1 68 ? -35.74985 -8.17431  16.47678  1.000 8.95734  ? 66  SER D CA  1 
ATOM   3318 C C   . SER E  1 68 ? -35.21755 -9.54389  16.86777  1.000 8.44125  ? 66  SER D C   1 
ATOM   3319 O O   . SER E  1 68 ? -34.15876 -9.96893  16.39479  1.000 9.07784  ? 66  SER D O   1 
ATOM   3320 C CB  . SER E  1 68 ? -36.38819 -8.24607  15.08929  1.000 10.10866 ? 66  SER D CB  1 
ATOM   3321 O OG  . SER E  1 68 ? -36.97325 -7.00750  14.74786  1.000 10.94691 ? 66  SER D OG  1 
ATOM   3322 N N   . THR E  1 69 ? -35.98029 -10.23244 17.71476  1.000 9.23728  ? 67  THR D N   1 
ATOM   3323 C CA  . THR E  1 69 ? -35.76433 -11.62815 18.07567  1.000 10.84123 ? 67  THR D CA  1 
ATOM   3324 C C   . THR E  1 69 ? -37.12101 -12.30209 17.97780  1.000 11.43953 ? 67  THR D C   1 
ATOM   3325 O O   . THR E  1 69 ? -38.08224 -11.85404 18.61327  1.000 11.39258 ? 67  THR D O   1 
ATOM   3326 C CB  . THR E  1 69 ? -35.23898 -11.74935 19.50938  1.000 13.18527 ? 67  THR D CB  1 
ATOM   3327 O OG1 . THR E  1 69 ? -33.99051 -11.05583 19.62966  1.000 14.21772 ? 67  THR D OG1 1 
ATOM   3328 C CG2 . THR E  1 69 ? -35.04538 -13.21461 19.89128  1.000 17.80744 ? 67  THR D CG2 1 
ATOM   3329 N N   . GLY E  1 70 ? -37.20410 -13.36108 17.18106  1.000 11.66569 ? 68  GLY D N   1 
ATOM   3330 C CA  . GLY E  1 70 ? -38.50768 -13.94990 16.93286  1.000 13.32272 ? 68  GLY D CA  1 
ATOM   3331 C C   . GLY E  1 70 ? -39.40742 -12.91172 16.29277  1.000 12.33000 ? 68  GLY D C   1 
ATOM   3332 O O   . GLY E  1 70 ? -39.02101 -12.22013 15.34300  1.000 13.09695 ? 68  GLY D O   1 
ATOM   3333 N N   . THR E  1 71 ? -40.61622 -12.76991 16.82184  1.000 12.38846 ? 69  THR D N   1 
ATOM   3334 C CA  . THR E  1 71 ? -41.56165 -11.79673 16.29542  1.000 13.89113 ? 69  THR D CA  1 
ATOM   3335 C C   . THR E  1 71 ? -41.57472 -10.48930 17.07812  1.000 11.69375 ? 69  THR D C   1 
ATOM   3336 O O   . THR E  1 71 ? -42.41945 -9.63193  16.80610  1.000 14.39445 ? 69  THR D O   1 
ATOM   3337 C CB  . THR E  1 71 ? -42.96953 -12.38722 16.23568  1.000 19.90405 ? 69  THR D CB  1 
ATOM   3338 O OG1 . THR E  1 71 ? -43.36310 -12.78994 17.55013  1.000 19.91199 ? 69  THR D OG1 1 
ATOM   3339 C CG2 . THR E  1 71 ? -43.00631 -13.58810 15.30050  1.000 23.11512 ? 69  THR D CG2 1 
ATOM   3340 N N   . THR E  1 72 ? -40.66260 -10.30775 18.02797  1.000 11.66613 ? 70  THR D N   1 
ATOM   3341 C CA  . THR E  1 72 ? -40.65490 -9.12334  18.87685  1.000 11.01075 ? 70  THR D CA  1 
ATOM   3342 C C   . THR E  1 72 ? -39.54125 -8.17695  18.45355  1.000 9.18642  ? 70  THR D C   1 
ATOM   3343 O O   . THR E  1 72 ? -38.36121 -8.54665  18.46896  1.000 10.34662 ? 70  THR D O   1 
ATOM   3344 C CB  . THR E  1 72 ? -40.48312 -9.49898  20.34611  1.000 13.35020 ? 70  THR D CB  1 
ATOM   3345 O OG1 . THR E  1 72 ? -41.58447 -10.31362 20.76499  1.000 19.22962 ? 70  THR D OG1 1 
ATOM   3346 C CG2 . THR E  1 72 ? -40.44636 -8.24513  21.20498  1.000 16.23690 ? 70  THR D CG2 1 
ATOM   3347 N N   . THR E  1 73 ? -39.92144 -6.95555  18.10400  1.000 8.87198  ? 71  THR D N   1 
ATOM   3348 C CA  . THR E  1 73 ? -38.98311 -5.89447  17.77748  1.000 8.21400  ? 71  THR D CA  1 
ATOM   3349 C C   . THR E  1 73 ? -38.97058 -4.88588  18.91435  1.000 7.19293  ? 71  THR D C   1 
ATOM   3350 O O   . THR E  1 73 ? -40.02512 -4.37184  19.30217  1.000 9.16733  ? 71  THR D O   1 
ATOM   3351 C CB  . THR E  1 73 ? -39.40922 -5.18813  16.49397  1.000 9.18622  ? 71  THR D CB  1 
ATOM   3352 O OG1 . THR E  1 73 ? -39.43520 -6.12690  15.41617  1.000 10.22520 ? 71  THR D OG1 1 
ATOM   3353 C CG2 . THR E  1 73 ? -38.46106 -4.04639  16.15924  1.000 9.38562  ? 71  THR D CG2 1 
ATOM   3354 N N   . THR E  1 74 ? -37.78442 -4.61045  19.44213  1.000 8.05114  ? 72  THR D N   1 
ATOM   3355 C CA  . THR E  1 74 ? -37.58651 -3.62031  20.49001  1.000 8.07717  ? 72  THR D CA  1 
ATOM   3356 C C   . THR E  1 74 ? -36.82514 -2.43679  19.91590  1.000 6.33800  ? 72  THR D C   1 
ATOM   3357 O O   . THR E  1 74 ? -35.80182 -2.61932  19.25026  1.000 7.58283  ? 72  THR D O   1 
ATOM   3358 C CB  . THR E  1 74 ? -36.80038 -4.22522  21.65865  1.000 8.43286  ? 72  THR D CB  1 
ATOM   3359 O OG1 . THR E  1 74 ? -37.46703 -5.40192  22.13630  1.000 9.95780  ? 72  THR D OG1 1 
ATOM   3360 C CG2 . THR E  1 74 ? -36.66892 -3.23215  22.79902  1.000 9.21210  ? 72  THR D CG2 1 
ATOM   3361 N N   . GLU E  1 75 ? -37.31995 -1.23393  20.17174  1.000 6.70915  ? 73  GLU D N   1 
ATOM   3362 C CA  . GLU E  1 75 ? -36.64288 -0.01069  19.77517  1.000 7.23041  ? 73  GLU D CA  1 
ATOM   3363 C C   . GLU E  1 75 ? -35.74708 0.45215   20.91090  1.000 6.69750  ? 73  GLU D C   1 
ATOM   3364 O O   . GLU E  1 75 ? -36.17251 0.48215   22.07351  1.000 7.50135  ? 73  GLU D O   1 
ATOM   3365 C CB  . GLU E  1 75 ? -37.67998 1.06495   19.48164  1.000 7.63242  ? 73  GLU D CB  1 
ATOM   3366 C CG  . GLU E  1 75 ? -37.13182 2.43222   19.11946  1.000 7.80285  ? 73  GLU D CG  1 
ATOM   3367 C CD  . GLU E  1 75 ? -38.23982 3.48141   19.08738  1.000 6.81826  ? 73  GLU D CD  1 
ATOM   3368 O OE1 . GLU E  1 75 ? -39.04257 3.51091   20.03816  1.000 7.99336  ? 73  GLU D OE1 1 
ATOM   3369 O OE2 . GLU E  1 75 ? -38.32041 4.25642   18.11512  1.000 7.97598  ? 73  GLU D OE2 1 
ATOM   3370 N N   . TRP E  1 76 ? -34.51850 0.81884   20.56382  1.000 6.77694  ? 74  TRP D N   1 
ATOM   3371 C CA  . TRP E  1 76 ? -33.54174 1.36708   21.48920  1.000 7.77207  ? 74  TRP D CA  1 
ATOM   3372 C C   . TRP E  1 76 ? -33.17120 2.76594   21.03074  1.000 6.89661  ? 74  TRP D C   1 
ATOM   3373 O O   . TRP E  1 76 ? -32.95446 3.00346   19.83998  1.000 7.72205  ? 74  TRP D O   1 
ATOM   3374 C CB  . TRP E  1 76 ? -32.30703 0.46620   21.57357  1.000 7.88246  ? 74  TRP D CB  1 
ATOM   3375 C CG  . TRP E  1 76 ? -32.63358 -0.85400  22.15247  1.000 8.05964  ? 74  TRP D CG  1 
ATOM   3376 C CD1 . TRP E  1 76 ? -32.84943 -2.02523  21.48456  1.000 8.26716  ? 74  TRP D CD1 1 
ATOM   3377 C CD2 . TRP E  1 76 ? -32.83790 -1.13294  23.53333  1.000 8.52534  ? 74  TRP D CD2 1 
ATOM   3378 N NE1 . TRP E  1 76 ? -33.16103 -3.02413  22.37568  1.000 9.47937  ? 74  TRP D NE1 1 
ATOM   3379 C CE2 . TRP E  1 76 ? -33.16020 -2.49651  23.64177  1.000 9.75548  ? 74  TRP D CE2 1 
ATOM   3380 C CE3 . TRP E  1 76 ? -32.77328 -0.35794  24.69448  1.000 9.31906  ? 74  TRP D CE3 1 
ATOM   3381 C CZ2 . TRP E  1 76 ? -33.41763 -3.10506  24.86858  1.000 11.19129 ? 74  TRP D CZ2 1 
ATOM   3382 C CZ3 . TRP E  1 76 ? -33.03341 -0.96615  25.91506  1.000 11.68308 ? 74  TRP D CZ3 1 
ATOM   3383 C CH2 . TRP E  1 76 ? -33.35105 -2.32372  25.98914  1.000 13.76231 ? 74  TRP D CH2 1 
ATOM   3384 N N   . CYS E  1 77 ? -33.10924 3.69252   21.97775  1.000 7.51069  ? 75  CYS D N   1 
ATOM   3385 C CA  . CYS E  1 77 ? -33.05099 5.11165   21.67948  1.000 7.44933  ? 75  CYS D CA  1 
ATOM   3386 C C   . CYS E  1 77 ? -31.79887 5.72594   22.27694  1.000 7.02861  ? 75  CYS D C   1 
ATOM   3387 O O   . CYS E  1 77 ? -31.54561 5.59293   23.48098  1.000 8.74857  ? 75  CYS D O   1 
ATOM   3388 C CB  . CYS E  1 77 ? -34.25535 5.82905   22.28129  1.000 8.05703  ? 75  CYS D CB  1 
ATOM   3389 S SG  . CYS E  1 77 ? -35.82997 5.09088   21.86431  1.000 9.00550  ? 75  CYS D SG  1 
ATOM   3390 N N   . TRP E  1 78 ? -31.05323 6.43777   21.45028  1.000 7.55403  ? 76  TRP D N   1 
ATOM   3391 C CA  . TRP E  1 78 ? -29.96497 7.28879   21.90214  1.000 9.21867  ? 76  TRP D CA  1 
ATOM   3392 C C   . TRP E  1 78 ? -30.38539 8.73080   21.69078  1.000 8.85828  ? 76  TRP D C   1 
ATOM   3393 O O   . TRP E  1 78 ? -30.66574 9.13996   20.56025  1.000 10.31697 ? 76  TRP D O   1 
ATOM   3394 C CB  . TRP E  1 78 ? -28.68733 7.02491   21.11719  1.000 9.05825  ? 76  TRP D CB  1 
ATOM   3395 C CG  . TRP E  1 78 ? -27.60392 7.96538   21.52270  1.000 10.50392 ? 76  TRP D CG  1 
ATOM   3396 C CD1 . TRP E  1 78 ? -27.31106 9.19052   20.98647  1.000 12.17453 ? 76  TRP D CD1 1 
ATOM   3397 C CD2 . TRP E  1 78 ? -26.68597 7.76446   22.58937  1.000 11.19527 ? 76  TRP D CD2 1 
ATOM   3398 N NE1 . TRP E  1 78 ? -26.25127 9.75667   21.65621  1.000 14.04569 ? 76  TRP D NE1 1 
ATOM   3399 C CE2 . TRP E  1 78 ? -25.84680 8.89672   22.64222  1.000 12.79880 ? 76  TRP D CE2 1 
ATOM   3400 C CE3 . TRP E  1 78 ? -26.48337 6.72861   23.50085  1.000 9.59584  ? 76  TRP D CE3 1 
ATOM   3401 C CZ2 . TRP E  1 78 ? -24.81965 9.02277   23.57680  1.000 13.42897 ? 76  TRP D CZ2 1 
ATOM   3402 C CZ3 . TRP E  1 78 ? -25.45674 6.85130   24.42297  1.000 12.09895 ? 76  TRP D CZ3 1 
ATOM   3403 C CH2 . TRP E  1 78 ? -24.64431 7.99341   24.45772  1.000 15.44860 ? 76  TRP D CH2 1 
ATOM   3404 N N   . ASP E  1 79 ? -30.41941 9.49790   22.77973  1.000 11.66273 ? 77  ASP D N   1 
ATOM   3405 C CA  . ASP E  1 79 ? -30.76681 10.91137  22.74083  1.000 13.11818 ? 77  ASP D CA  1 
ATOM   3406 C C   . ASP E  1 79 ? -29.72187 11.74243  23.48074  1.000 15.49371 ? 77  ASP D C   1 
ATOM   3407 O O   . ASP E  1 79 ? -30.03753 12.78710  24.05716  1.000 17.83819 ? 77  ASP D O   1 
ATOM   3408 C CB  . ASP E  1 79 ? -32.17116 11.14936  23.29623  1.000 14.45337 ? 77  ASP D CB  1 
ATOM   3409 C CG  . ASP E  1 79 ? -33.25537 10.47636  22.46040  1.000 17.66920 ? 77  ASP D CG  1 
ATOM   3410 O OD1 . ASP E  1 79 ? -33.36183 10.78496  21.25483  1.000 12.40370 ? 77  ASP D OD1 1 
ATOM   3411 O OD2 . ASP E  1 79 ? -34.00188 9.63532   23.00998  1.000 21.52532 ? 77  ASP D OD2 1 
ATOM   3412 N N   . GLY E  1 80 ? -28.47147 11.28257  23.48272  1.000 15.83371 ? 78  GLY D N   1 
ATOM   3413 C CA  . GLY E  1 80 ? -27.36130 12.04115  24.01638  1.000 22.03612 ? 78  GLY D CA  1 
ATOM   3414 C C   . GLY E  1 80 ? -26.90213 11.63507  25.39927  1.000 24.04800 ? 78  GLY D C   1 
ATOM   3415 O O   . GLY E  1 80 ? -25.88217 12.15585  25.86825  1.000 27.71778 ? 78  GLY D O   1 
ATOM   3416 N N   . ASN E  1 81 ? -27.60259 10.72002  26.05797  1.000 18.21055 ? 79  ASN D N   1 
ATOM   3417 C CA  . ASN E  1 81 ? -27.31564 10.39881  27.45017  1.000 25.24320 ? 79  ASN D CA  1 
ATOM   3418 C C   . ASN E  1 81 ? -27.72672 8.95755   27.75096  1.000 25.42365 ? 79  ASN D C   1 
ATOM   3419 O O   . ASN E  1 81 ? -28.49773 8.67398   28.66320  1.000 28.65017 ? 79  ASN D O   1 
ATOM   3420 C CB  . ASN E  1 81 ? -28.02218 11.39514  28.36744  1.000 27.11767 ? 79  ASN D CB  1 
ATOM   3421 C CG  . ASN E  1 81 ? -27.20904 11.73476  29.60008  1.000 48.26043 ? 79  ASN D CG  1 
ATOM   3422 O OD1 . ASN E  1 81 ? -26.36467 10.95312  30.03935  1.000 51.95647 ? 79  ASN D OD1 1 
ATOM   3423 N ND2 . ASN E  1 81 ? -27.46111 12.90913  30.16670  1.000 55.58150 ? 79  ASN D ND2 1 
ATOM   3424 N N   . GLY E  1 82 ? -27.21480 8.01396   26.97014  1.000 17.43864 ? 80  GLY D N   1 
ATOM   3425 C CA  . GLY E  1 82 ? -27.44440 6.60821   27.22303  1.000 14.21468 ? 80  GLY D CA  1 
ATOM   3426 C C   . GLY E  1 82 ? -28.53436 6.02982   26.33466  1.000 11.07473 ? 80  GLY D C   1 
ATOM   3427 O O   . GLY E  1 82 ? -29.35754 6.74409   25.75840  1.000 15.29557 ? 80  GLY D O   1 
ATOM   3428 N N   . TRP E  1 83 ? -28.53973 4.70248   26.23636  1.000 10.47638 ? 81  TRP D N   1 
ATOM   3429 C CA  . TRP E  1 83 ? -29.54937 3.98515   25.46668  1.000 9.53897  ? 81  TRP D CA  1 
ATOM   3430 C C   . TRP E  1 83 ? -30.72990 3.64351   26.36325  1.000 9.72226  ? 81  TRP D C   1 
ATOM   3431 O O   . TRP E  1 83 ? -30.54820 3.16209   27.48770  1.000 14.90500 ? 81  TRP D O   1 
ATOM   3432 C CB  . TRP E  1 83 ? -28.95655 2.71146   24.86396  1.000 10.60360 ? 81  TRP D CB  1 
ATOM   3433 C CG  . TRP E  1 83 ? -27.96916 2.98665   23.77592  1.000 9.11684  ? 81  TRP D CG  1 
ATOM   3434 C CD1 . TRP E  1 83 ? -26.61279 3.08829   23.90104  1.000 9.36665  ? 81  TRP D CD1 1 
ATOM   3435 C CD2 . TRP E  1 83 ? -28.26607 3.22112   22.39745  1.000 8.06465  ? 81  TRP D CD2 1 
ATOM   3436 N NE1 . TRP E  1 83 ? -26.04520 3.34736   22.67890  1.000 8.95442  ? 81  TRP D NE1 1 
ATOM   3437 C CE2 . TRP E  1 83 ? -27.03953 3.44432   21.74080  1.000 7.62974  ? 81  TRP D CE2 1 
ATOM   3438 C CE3 . TRP E  1 83 ? -29.44868 3.25302   21.65111  1.000 8.27309  ? 81  TRP D CE3 1 
ATOM   3439 C CZ2 . TRP E  1 83 ? -26.96259 3.69490   20.37544  1.000 7.63999  ? 81  TRP D CZ2 1 
ATOM   3440 C CZ3 . TRP E  1 83 ? -29.37026 3.49948   20.29537  1.000 8.74656  ? 81  TRP D CZ3 1 
ATOM   3441 C CH2 . TRP E  1 83 ? -28.13898 3.71240   19.67048  1.000 8.25909  ? 81  TRP D CH2 1 
ATOM   3442 N N   . THR E  1 84 ? -31.93612 3.88689   25.86194  1.000 8.28718  ? 82  THR D N   1 
ATOM   3443 C CA  . THR E  1 84 ? -33.15874 3.59170   26.59578  1.000 9.45097  ? 82  THR D CA  1 
ATOM   3444 C C   . THR E  1 84 ? -34.14367 2.89630   25.67052  1.000 8.16170  ? 82  THR D C   1 
ATOM   3445 O O   . THR E  1 84 ? -34.15850 3.14774   24.46366  1.000 9.67931  ? 82  THR D O   1 
ATOM   3446 C CB  . THR E  1 84 ? -33.80714 4.88508   27.10581  1.000 11.02036 ? 82  THR D CB  1 
ATOM   3447 O OG1 . THR E  1 84 ? -34.19141 5.69994   25.99595  1.000 19.11015 ? 82  THR D OG1 1 
ATOM   3448 C CG2 . THR E  1 84 ? -32.83606 5.67093   27.96875  1.000 15.31764 ? 82  THR D CG2 1 
ATOM   3449 N N   . LYS E  1 85 ? -34.97896 2.03210   26.23485  1.000 8.58258  ? 83  LYS D N   1 
ATOM   3450 C CA  . LYS E  1 85 ? -36.00467 1.39392   25.42761  1.000 9.49880  ? 83  LYS D CA  1 
ATOM   3451 C C   . LYS E  1 85 ? -37.02417 2.42452   24.95798  1.000 10.70143 ? 83  LYS D C   1 
ATOM   3452 O O   . LYS E  1 85 ? -37.44732 3.30782   25.71432  1.000 12.41480 ? 83  LYS D O   1 
ATOM   3453 C CB  . LYS E  1 85 ? -36.69705 0.29095   26.21807  1.000 10.30182 ? 83  LYS D CB  1 
ATOM   3454 C CG  . LYS E  1 85 ? -37.80166 -0.39029  25.44028  1.000 11.14266 ? 83  LYS D CG  1 
ATOM   3455 C CD  . LYS E  1 85 ? -38.47142 -1.47380  26.25983  1.000 13.19855 ? 83  LYS D CD  1 
ATOM   3456 C CE  . LYS E  1 85 ? -39.65951 -2.04167  25.50597  1.000 14.52426 ? 83  LYS D CE  1 
ATOM   3457 N NZ  . LYS E  1 85 ? -40.40629 -3.05671  26.30466  1.000 14.42156 ? 83  LYS D NZ  1 
ATOM   3458 N N   . GLY E  1 86 ? -37.41069 2.31772   23.69750  1.000 9.32930  ? 84  GLY D N   1 
ATOM   3459 C CA  . GLY E  1 86 ? -38.40007 3.21583   23.14618  1.000 10.67153 ? 84  GLY D CA  1 
ATOM   3460 C C   . GLY E  1 86 ? -39.82229 2.68966   23.25024  1.000 8.25879  ? 84  GLY D C   1 
ATOM   3461 O O   . GLY E  1 86 ? -40.08219 1.54615   23.62094  1.000 8.77638  ? 84  GLY D O   1 
ATOM   3462 N N   . ALA E  1 87 ? -40.75477 3.55686   22.86930  1.000 8.68952  ? 85  ALA D N   1 
ATOM   3463 C CA  . ALA E  1 87 ? -42.17342 3.23632   22.91702  1.000 8.79434  ? 85  ALA D CA  1 
ATOM   3464 C C   . ALA E  1 87 ? -42.63672 2.33579   21.77760  1.000 8.41383  ? 85  ALA D C   1 
ATOM   3465 O O   . ALA E  1 87 ? -43.79452 1.90089   21.79587  1.000 8.71416  ? 85  ALA D O   1 
ATOM   3466 C CB  . ALA E  1 87 ? -42.98835 4.53409   22.91424  1.000 10.65443 ? 85  ALA D CB  1 
ATOM   3467 N N   . TYR E  1 88 ? -41.78642 2.04113   20.79503  1.000 7.36948  ? 86  TYR D N   1 
ATOM   3468 C CA  . TYR E  1 88 ? -42.21792 1.22920   19.66622  1.000 7.65153  ? 86  TYR D CA  1 
ATOM   3469 C C   . TYR E  1 88 ? -42.79678 -0.09271  20.13475  1.000 6.96182  ? 86  TYR D C   1 
ATOM   3470 O O   . TYR E  1 88 ? -42.20271 -0.79135  20.96194  1.000 7.88011  ? 86  TYR D O   1 
ATOM   3471 C CB  . TYR E  1 88 ? -41.04379 0.93461   18.74319  1.000 7.76874  ? 86  TYR D CB  1 
ATOM   3472 C CG  . TYR E  1 88 ? -41.41709 0.03704   17.57934  1.000 7.67602  ? 86  TYR D CG  1 
ATOM   3473 C CD1 . TYR E  1 88 ? -41.33522 -1.35125  17.67795  1.000 8.83040  ? 86  TYR D CD1 1 
ATOM   3474 C CD2 . TYR E  1 88 ? -41.86698 0.58026   16.38256  1.000 6.87250  ? 86  TYR D CD2 1 
ATOM   3475 C CE1 . TYR E  1 88 ? -41.69225 -2.16732  16.62091  1.000 9.46410  ? 86  TYR D CE1 1 
ATOM   3476 C CE2 . TYR E  1 88 ? -42.21121 -0.22737  15.31842  1.000 8.10102  ? 86  TYR D CE2 1 
ATOM   3477 C CZ  . TYR E  1 88 ? -42.12097 -1.59496  15.43908  1.000 8.05878  ? 86  TYR D CZ  1 
ATOM   3478 O OH  . TYR E  1 88 ? -42.47056 -2.39868  14.37913  1.000 10.49192 ? 86  TYR D OH  1 
ATOM   3479 N N   . THR E  1 89 ? -43.95916 -0.43527  19.58543  1.000 7.27854  ? 87  THR D N   1 
ATOM   3480 C CA  . THR E  1 89 ? -44.51748 -1.76708  19.70403  1.000 8.33235  ? 87  THR D CA  1 
ATOM   3481 C C   . THR E  1 89 ? -45.11109 -2.15136  18.36140  1.000 8.51901  ? 87  THR D C   1 
ATOM   3482 O O   . THR E  1 89 ? -45.42424 -1.30087  17.52584  1.000 9.10711  ? 87  THR D O   1 
ATOM   3483 C CB  . THR E  1 89 ? -45.63568 -1.84342  20.75151  1.000 9.92839  ? 87  THR D CB  1 
ATOM   3484 O OG1 . THR E  1 89 ? -46.70902 -0.98031  20.35191  1.000 10.73083 ? 87  THR D OG1 1 
ATOM   3485 C CG2 . THR E  1 89 ? -45.13819 -1.44599  22.14075  1.000 10.90344 ? 87  THR D CG2 1 
ATOM   3486 N N   . ALA E  1 90 ? -45.29238 -3.45347  18.18579  1.000 10.21825 ? 88  ALA D N   1 
ATOM   3487 C CA  . ALA E  1 90 ? -45.97186 -3.99838  17.02590  1.000 12.15099 ? 88  ALA D CA  1 
ATOM   3488 C C   . ALA E  1 90 ? -46.62257 -5.30644  17.44345  1.000 14.15143 ? 88  ALA D C   1 
ATOM   3489 O O   . ALA E  1 90 ? -46.31440 -5.86325  18.50023  1.000 18.53465 ? 88  ALA D O   1 
ATOM   3490 C CB  . ALA E  1 90 ? -45.00091 -4.22041  15.86536  1.000 14.33543 ? 88  ALA D CB  1 
ATOM   3491 N N   . THR E  1 91 ? -47.54876 -5.78303  16.61693  1.000 17.07376 ? 89  THR D N   1 
ATOM   3492 C CA  . THR E  1 91 ? -48.19790 -7.07513  16.83473  1.000 17.09390 ? 89  THR D CA  1 
ATOM   3493 C C   . THR E  1 91 ? -47.86148 -7.96031  15.63971  1.000 24.24971 ? 89  THR D C   1 
ATOM   3494 O O   . THR E  1 91 ? -48.59735 -8.00111  14.65101  1.000 30.59093 ? 89  THR D O   1 
ATOM   3495 C CB  . THR E  1 91 ? -49.70793 -6.93058  17.05226  1.000 25.35846 ? 89  THR D CB  1 
ATOM   3496 O OG1 . THR E  1 91 ? -50.27201 -6.12742  16.00798  1.000 39.33205 ? 89  THR D OG1 1 
ATOM   3497 C CG2 . THR E  1 91 ? -49.98471 -6.28206  18.39865  1.000 23.89227 ? 89  THR D CG2 1 
ATOM   3498 N N   . ASN E  1 92 ? -46.73509 -8.65909  15.73842  1.000 20.67638 ? 90  ASN D N   1 
ATOM   3499 C CA  . ASN E  1 92 ? -46.26424 -9.53452  14.67547  1.000 22.23430 ? 90  ASN D CA  1 
ATOM   3500 C C   . ASN E  1 92 ? -46.68677 -10.97696 14.94232  1.000 32.54303 ? 90  ASN D C   1 
ATOM   3501 O O   . ASN E  1 92 ? -46.80035 -11.39784 16.09650  1.000 36.46572 ? 90  ASN D O   1 
ATOM   3502 C CB  . ASN E  1 92 ? -44.73780 -9.44547  14.56087  1.000 22.04099 ? 90  ASN D CB  1 
ATOM   3503 C CG  . ASN E  1 92 ? -44.25610 -8.04040  14.22832  1.000 20.90789 ? 90  ASN D CG  1 
ATOM   3504 O OD1 . ASN E  1 92 ? -44.79085 -7.38614  13.33521  1.000 19.16586 ? 90  ASN D OD1 1 
ATOM   3505 N ND2 . ASN E  1 92 ? -43.25032 -7.56613  14.95724  1.000 14.90036 ? 90  ASN D ND2 1 
ATOM   3506 N N   . MET F  1 1  ? -31.41223 -12.91164 8.42558   1.000 48.70694 ? -1  MET A N   1 
ATOM   3507 C CA  . MET F  1 1  ? -31.60725 -13.99917 9.38003   1.000 57.55432 ? -1  MET A CA  1 
ATOM   3508 C C   . MET F  1 1  ? -33.06995 -14.45083 9.41316   1.000 58.82719 ? -1  MET A C   1 
ATOM   3509 O O   . MET F  1 1  ? -33.96065 -13.68113 9.77535   1.000 48.71893 ? -1  MET A O   1 
ATOM   3510 C CB  . MET F  1 1  ? -31.12687 -13.56397 10.77213  1.000 55.00445 ? -1  MET A CB  1 
ATOM   3511 C CG  . MET F  1 1  ? -31.43101 -14.52510 11.92044  1.000 37.70056 ? -1  MET A CG  1 
ATOM   3512 S SD  . MET F  1 1  ? -30.30422 -15.92946 12.02515  1.000 74.65509 ? -1  MET A SD  1 
ATOM   3513 C CE  . MET F  1 1  ? -31.18822 -17.18326 11.12332  1.000 65.48901 ? -1  MET A CE  1 
ATOM   3514 N N   . LYS F  1 2  ? -33.30249 -15.70562 9.02898   1.000 60.55459 ? 0   LYS A N   1 
ATOM   3515 C CA  . LYS F  1 2  ? -34.64395 -16.27110 9.00247   1.000 59.23559 ? 0   LYS A CA  1 
ATOM   3516 C C   . LYS F  1 2  ? -35.19494 -16.41509 10.42316  1.000 51.52981 ? 0   LYS A C   1 
ATOM   3517 O O   . LYS F  1 2  ? -34.53850 -16.08548 11.41761  1.000 49.40320 ? 0   LYS A O   1 
ATOM   3518 C CB  . LYS F  1 2  ? -34.63837 -17.61879 8.28203   1.000 61.70786 ? 0   LYS A CB  1 
ATOM   3519 C CG  . LYS F  1 2  ? -33.77460 -18.67885 8.95120   1.000 59.25900 ? 0   LYS A CG  1 
ATOM   3520 C CD  . LYS F  1 2  ? -33.97681 -20.04595 8.31907   1.000 59.26779 ? 0   LYS A CD  1 
ATOM   3521 C CE  . LYS F  1 2  ? -33.16600 -21.10564 9.04537   1.000 54.77601 ? 0   LYS A CE  1 
ATOM   3522 N NZ  . LYS F  1 2  ? -33.47935 -21.12529 10.50109  1.000 48.19682 ? 0   LYS A NZ  1 
ATOM   3523 N N   . ALA F  1 3  ? -36.42733 -16.92628 10.50330  1.000 45.44925 ? 1   ALA A N   1 
ATOM   3524 C CA  . ALA F  1 3  ? -37.17233 -17.09061 11.75027  1.000 56.71795 ? 1   ALA A CA  1 
ATOM   3525 C C   . ALA F  1 3  ? -37.56677 -15.74925 12.36323  1.000 53.54614 ? 1   ALA A C   1 
ATOM   3526 O O   . ALA F  1 3  ? -38.75892 -15.43552 12.45517  1.000 39.59597 ? 1   ALA A O   1 
ATOM   3527 C CB  . ALA F  1 3  ? -36.42911 -17.98429 12.75176  1.000 48.59665 ? 1   ALA A CB  1 
ATOM   3528 N N   . SER F  1 4  ? -36.58647 -14.95098 12.78249  1.000 29.63274 ? 2   SER A N   1 
ATOM   3529 C CA  . SER F  1 4  ? -36.89267 -13.64077 13.34116  1.000 17.10103 ? 2   SER A CA  1 
ATOM   3530 C C   . SER F  1 4  ? -37.36767 -12.69495 12.24430  1.000 13.23755 ? 2   SER A C   1 
ATOM   3531 O O   . SER F  1 4  ? -36.85469 -12.71230 11.12052  1.000 15.04458 ? 2   SER A O   1 
ATOM   3532 C CB  . SER F  1 4  ? -35.66682 -13.05754 14.04744  1.000 19.71607 ? 2   SER A CB  1 
ATOM   3533 O OG  . SER F  1 4  ? -35.35399 -13.79025 15.22528  1.000 20.00621 ? 2   SER A OG  1 
ATOM   3534 N N   . VAL F  1 5  ? -38.36905 -11.87359 12.57775  1.000 12.05284 ? 3   VAL A N   1 
ATOM   3535 C CA  . VAL F  1 5  ? -38.85027 -10.86847 11.63791  1.000 10.72886 ? 3   VAL A CA  1 
ATOM   3536 C C   . VAL F  1 5  ? -37.70420 -9.94044  11.23683  1.000 10.22137 ? 3   VAL A C   1 
ATOM   3537 O O   . VAL F  1 5  ? -36.69110 -9.81540  11.93305  1.000 11.74139 ? 3   VAL A O   1 
ATOM   3538 C CB  . VAL F  1 5  ? -40.03508 -10.07531 12.21022  1.000 10.05186 ? 3   VAL A CB  1 
ATOM   3539 C CG1 . VAL F  1 5  ? -41.18500 -11.01543 12.53454  1.000 12.72148 ? 3   VAL A CG1 1 
ATOM   3540 C CG2 . VAL F  1 5  ? -39.61587 -9.27176  13.43429  1.000 10.94893 ? 3   VAL A CG2 1 
ATOM   3541 N N   . GLN F  1 6  ? -37.87223 -9.28258  10.09512  1.000 9.57338  ? 4   GLN A N   1 
ATOM   3542 C CA  . GLN F  1 6  ? -36.84499 -8.41703  9.53767   1.000 8.37645  ? 4   GLN A CA  1 
ATOM   3543 C C   . GLN F  1 6  ? -37.44469 -7.03338  9.33488   1.000 7.82290  ? 4   GLN A C   1 
ATOM   3544 O O   . GLN F  1 6  ? -38.56988 -6.90901  8.84041   1.000 9.62509  ? 4   GLN A O   1 
ATOM   3545 C CB  . GLN F  1 6  ? -36.35967 -8.99876  8.20717   1.000 10.76099 ? 4   GLN A CB  1 
ATOM   3546 C CG  . GLN F  1 6  ? -35.22316 -8.24534  7.54658   1.000 12.57064 ? 4   GLN A CG  1 
ATOM   3547 C CD  . GLN F  1 6  ? -35.71397 -7.29171  6.48274   1.000 11.72517 ? 4   GLN A CD  1 
ATOM   3548 O OE1 . GLN F  1 6  ? -36.62210 -7.61073  5.71813   1.000 13.38496 ? 4   GLN A OE1 1 
ATOM   3549 N NE2 . GLN F  1 6  ? -35.11184 -6.11365  6.42200   1.000 16.01162 ? 4   GLN A NE2 1 
ATOM   3550 N N   . THR F  1 7  ? -36.71567 -5.99111  9.73176   1.000 7.84191  ? 5   THR A N   1 
ATOM   3551 C CA  . THR F  1 7  ? -37.26117 -4.64603  9.69174   1.000 7.27118  ? 5   THR A CA  1 
ATOM   3552 C C   . THR F  1 7  ? -36.39089 -3.70480  8.87390   1.000 6.33495  ? 5   THR A C   1 
ATOM   3553 O O   . THR F  1 7  ? -35.22327 -3.97371  8.57179   1.000 7.45218  ? 5   THR A O   1 
ATOM   3554 C CB  . THR F  1 7  ? -37.46083 -4.02978  11.09066  1.000 7.42349  ? 5   THR A CB  1 
ATOM   3555 O OG1 . THR F  1 7  ? -36.19017 -3.70818  11.67218  1.000 8.41855  ? 5   THR A OG1 1 
ATOM   3556 C CG2 . THR F  1 7  ? -38.25927 -4.95878  12.01029  1.000 9.22936  ? 5   THR A CG2 1 
ATOM   3557 N N   . ALA F  1 8  ? -37.00019 -2.58234  8.52495   1.000 6.12273  ? 6   ALA A N   1 
ATOM   3558 C CA  . ALA F  1 8  ? -36.33471 -1.46116  7.88862   1.000 6.74526  ? 6   ALA A CA  1 
ATOM   3559 C C   . ALA F  1 8  ? -36.98241 -0.19640  8.42076   1.000 5.73551  ? 6   ALA A C   1 
ATOM   3560 O O   . ALA F  1 8  ? -38.18739 -0.16974  8.68393   1.000 7.64298  ? 6   ALA A O   1 
ATOM   3561 C CB  . ALA F  1 8  ? -36.48549 -1.50239  6.36745   1.000 8.44015  ? 6   ALA A CB  1 
ATOM   3562 N N   . ALA F  1 9  ? -36.18718 0.85896   8.58192   1.000 6.29939  ? 7   ALA A N   1 
ATOM   3563 C CA  . ALA F  1 9  ? -36.67856 2.07366   9.21545   1.000 6.21587  ? 7   ALA A CA  1 
ATOM   3564 C C   . ALA F  1 9  ? -36.20398 3.30478   8.45569   1.000 6.26625  ? 7   ALA A C   1 
ATOM   3565 O O   . ALA F  1 9  ? -35.09372 3.33494   7.92348   1.000 6.57575  ? 7   ALA A O   1 
ATOM   3566 C CB  . ALA F  1 9  ? -36.21062 2.17783   10.68094  1.000 8.82171  ? 7   ALA A CB  1 
ATOM   3567 N N   . THR F  1 10 ? -37.03668 4.34376   8.45366   1.000 6.26414  ? 8   THR A N   1 
ATOM   3568 C CA  . THR F  1 10 ? -36.65477 5.64935   7.93731   1.000 6.53407  ? 8   THR A CA  1 
ATOM   3569 C C   . THR F  1 10 ? -37.29393 6.72037   8.81301   1.000 5.94220  ? 8   THR A C   1 
ATOM   3570 O O   . THR F  1 10 ? -38.22994 6.45423   9.57052   1.000 7.02718  ? 8   THR A O   1 
ATOM   3571 C CB  . THR F  1 10 ? -37.05618 5.80719   6.45514   1.000 6.86515  ? 8   THR A CB  1 
ATOM   3572 O OG1 . THR F  1 10 ? -36.44059 6.97205   5.89031   1.000 8.43579  ? 8   THR A OG1 1 
ATOM   3573 C CG2 . THR F  1 10 ? -38.55913 5.93358   6.28498   1.000 8.33329  ? 8   THR A CG2 1 
ATOM   3574 N N   . SER F  1 11 ? -36.78220 7.94324   8.70607   1.000 6.50347  ? 9   SER A N   1 
ATOM   3575 C CA  . SER F  1 11 ? -37.28615 9.04122   9.51562   1.000 6.40828  ? 9   SER A CA  1 
ATOM   3576 C C   . SER F  1 11 ? -37.04329 10.34548  8.77861   1.000 6.52212  ? 9   SER A C   1 
ATOM   3577 O O   . SER F  1 11 ? -36.18656 10.42095  7.89896   1.000 7.46630  ? 9   SER A O   1 
ATOM   3578 C CB  . SER F  1 11 ? -36.62611 9.06584   10.90075  1.000 8.07464  ? 9   SER A CB  1 
ATOM   3579 O OG  . SER F  1 11 ? -35.22226 9.24972   10.80279  1.000 7.51374  ? 9   SER A OG  1 
ATOM   3580 N N   . TRP F  1 12 ? -37.80529 11.37878  9.14092   1.000 7.01846  ? 10  TRP A N   1 
ATOM   3581 C CA  . TRP F  1 12 ? -37.64632 12.66185  8.47139   1.000 7.85551  ? 10  TRP A CA  1 
ATOM   3582 C C   . TRP F  1 12 ? -38.08909 13.81222  9.36010   1.000 7.83405  ? 10  TRP A C   1 
ATOM   3583 O O   . TRP F  1 12 ? -38.93656 13.65570  10.24561  1.000 7.98576  ? 10  TRP A O   1 
ATOM   3584 C CB  . TRP F  1 12 ? -38.40775 12.73015  7.14621   1.000 8.93378  ? 10  TRP A CB  1 
ATOM   3585 C CG  . TRP F  1 12 ? -39.90105 12.62072  7.24988   1.000 7.95416  ? 10  TRP A CG  1 
ATOM   3586 C CD1 . TRP F  1 12 ? -40.80033 13.63726  7.42442   1.000 10.28879 ? 10  TRP A CD1 1 
ATOM   3587 C CD2 . TRP F  1 12 ? -40.67276 11.41949  7.13570   1.000 7.89976  ? 10  TRP A CD2 1 
ATOM   3588 N NE1 . TRP F  1 12 ? -42.07778 13.13828  7.42776   1.000 10.32964 ? 10  TRP A NE1 1 
ATOM   3589 C CE2 . TRP F  1 12 ? -42.02655 11.78104  7.24595   1.000 8.74187  ? 10  TRP A CE2 1 
ATOM   3590 C CE3 . TRP F  1 12 ? -40.34840 10.07433  6.93588   1.000 8.44533  ? 10  TRP A CE3 1 
ATOM   3591 C CZ2 . TRP F  1 12 ? -43.05795 10.84542  7.17854   1.000 9.72550  ? 10  TRP A CZ2 1 
ATOM   3592 C CZ3 . TRP F  1 12 ? -41.37557 9.14748   6.87531   1.000 8.52259  ? 10  TRP A CZ3 1 
ATOM   3593 C CH2 . TRP F  1 12 ? -42.71501 9.53661   6.99331   1.000 9.85303  ? 10  TRP A CH2 1 
ATOM   3594 N N   . GLY F  1 13 ? -37.51005 14.97611  9.09505   1.000 8.49967  ? 11  GLY A N   1 
ATOM   3595 C CA  . GLY F  1 13 ? -37.94250 16.19679  9.72858   1.000 10.38972 ? 11  GLY A CA  1 
ATOM   3596 C C   . GLY F  1 13 ? -37.46977 16.32153  11.16139  1.000 10.75544 ? 11  GLY A C   1 
ATOM   3597 O O   . GLY F  1 13 ? -36.59715 15.59539  11.64191  1.000 13.08270 ? 11  GLY A O   1 
ATOM   3598 N N   . THR F  1 14 ? -38.08077 17.27819  11.85783  1.000 11.58137 ? 12  THR A N   1 
ATOM   3599 C CA  . THR F  1 14 ? -37.63998 17.67192  13.18928  1.000 13.19967 ? 12  THR A CA  1 
ATOM   3600 C C   . THR F  1 14 ? -38.46499 17.05513  14.31078  1.000 13.20537 ? 12  THR A C   1 
ATOM   3601 O O   . THR F  1 14 ? -38.03868 17.10989  15.46927  1.000 16.40778 ? 12  THR A O   1 
ATOM   3602 C CB  . THR F  1 14 ? -37.66388 19.20386  13.32392  1.000 14.21370 ? 12  THR A CB  1 
ATOM   3603 O OG1 . THR F  1 14 ? -38.91364 19.70706  12.83565  1.000 19.70964 ? 12  THR A OG1 1 
ATOM   3604 C CG2 . THR F  1 14 ? -36.51624 19.82194  12.53026  1.000 23.38610 ? 12  THR A CG2 1 
ATOM   3605 N N   . VAL F  1 15 ? -39.62951 16.48558  14.00395  1.000 12.06539 ? 13  VAL A N   1 
ATOM   3606 C CA  . VAL F  1 15 ? -40.47781 15.90797  15.05361  1.000 12.55366 ? 13  VAL A CA  1 
ATOM   3607 C C   . VAL F  1 15 ? -39.81936 14.72966  15.76763  1.000 10.54561 ? 13  VAL A C   1 
ATOM   3608 O O   . VAL F  1 15 ? -39.81702 14.71107  17.01032  1.000 13.43802 ? 13  VAL A O   1 
ATOM   3609 C CB  . VAL F  1 15 ? -41.88593 15.62563  14.51145  1.000 12.59173 ? 13  VAL A CB  1 
ATOM   3610 C CG1 . VAL F  1 15 ? -42.74876 14.94856  15.56673  1.000 15.27908 ? 13  VAL A CG1 1 
ATOM   3611 C CG2 . VAL F  1 15 ? -42.53999 16.91565  14.02265  1.000 17.24967 ? 13  VAL A CG2 1 
ATOM   3612 N N   . PRO F  1 16 ? -39.28846 13.70948  15.07730  1.000 9.82837  ? 14  PRO A N   1 
ATOM   3613 C CA  . PRO F  1 16 ? -39.37372 13.44766  13.64767  1.000 8.16157  ? 14  PRO A CA  1 
ATOM   3614 C C   . PRO F  1 16 ? -40.58779 12.56951  13.40752  1.000 7.85776  ? 14  PRO A C   1 
ATOM   3615 O O   . PRO F  1 16 ? -41.24574 12.09664  14.34045  1.000 9.38547  ? 14  PRO A O   1 
ATOM   3616 C CB  . PRO F  1 16 ? -38.11189 12.62638  13.39859  1.000 9.14359  ? 14  PRO A CB  1 
ATOM   3617 C CG  . PRO F  1 16 ? -38.05831 11.75413  14.61154  1.000 10.64083 ? 14  PRO A CG  1 
ATOM   3618 C CD  . PRO F  1 16 ? -38.51014 12.65569  15.75476  1.000 11.07374 ? 14  PRO A CD  1 
ATOM   3619 N N   . SER F  1 17 ? -40.89858 12.32013  12.14342  1.000 7.94187  ? 15  SER A N   1 
ATOM   3620 C CA  . SER F  1 17 ? -41.71749 11.17524  11.78384  1.000 7.26809  ? 15  SER A CA  1 
ATOM   3621 C C   . SER F  1 17 ? -40.79976 9.98328   11.54893  1.000 6.26413  ? 15  SER A C   1 
ATOM   3622 O O   . SER F  1 17 ? -39.69528 10.13864  11.01985  1.000 7.73953  ? 15  SER A O   1 
ATOM   3623 C CB  . SER F  1 17 ? -42.52082 11.45479  10.51708  1.000 8.86038  ? 15  SER A CB  1 
ATOM   3624 O OG  . SER F  1 17 ? -43.61694 12.30982  10.77353  1.000 10.18940 ? 15  SER A OG  1 
ATOM   3625 N N   . ILE F  1 18 ? -41.26014 8.79771   11.94718  1.000 6.13664  ? 16  ILE A N   1 
ATOM   3626 C CA  . ILE F  1 18 ? -40.53351 7.54700   11.76314  1.000 6.68195  ? 16  ILE A CA  1 
ATOM   3627 C C   . ILE F  1 18 ? -41.49892 6.55717   11.13389  1.000 6.03965  ? 16  ILE A C   1 
ATOM   3628 O O   . ILE F  1 18 ? -42.68641 6.53543   11.47978  1.000 6.48916  ? 16  ILE A O   1 
ATOM   3629 C CB  . ILE F  1 18 ? -39.99744 6.96873   13.09776  1.000 6.45256  ? 16  ILE A CB  1 
ATOM   3630 C CG1 . ILE F  1 18 ? -39.27027 8.03214   13.92811  1.000 8.21686  ? 16  ILE A CG1 1 
ATOM   3631 C CG2 . ILE F  1 18 ? -39.10678 5.74195   12.84313  1.000 7.19621  ? 16  ILE A CG2 1 
ATOM   3632 C CD1 . ILE F  1 18 ? -38.93817 7.57313   15.33916  1.000 8.45178  ? 16  ILE A CD1 1 
ATOM   3633 N N   . ARG F  1 19 ? -41.00317 5.74510   10.20780  1.000 6.52366  ? 17  ARG A N   1 
ATOM   3634 C CA  . ARG F  1 19 ? -41.76003 4.61487   9.69110   1.000 6.31900  ? 17  ARG A CA  1 
ATOM   3635 C C   . ARG F  1 19 ? -40.89425 3.37040   9.81143   1.000 5.90923  ? 17  ARG A C   1 
ATOM   3636 O O   . ARG F  1 19 ? -39.71837 3.39517   9.42361   1.000 7.22937  ? 17  ARG A O   1 
ATOM   3637 C CB  . ARG F  1 19 ? -42.14942 4.85036   8.22808   1.000 6.87607  ? 17  ARG A CB  1 
ATOM   3638 C CG  . ARG F  1 19 ? -43.05084 6.06794   7.99478   1.000 7.10081  ? 17  ARG A CG  1 
ATOM   3639 C CD  . ARG F  1 19 ? -44.42282 5.87288   8.62465   1.000 7.00195  ? 17  ARG A CD  1 
ATOM   3640 N NE  . ARG F  1 19 ? -45.33381 6.98437   8.37659   1.000 7.63844  ? 17  ARG A NE  1 
ATOM   3641 C CZ  . ARG F  1 19 ? -45.44986 8.05783   9.14816   1.000 7.39805  ? 17  ARG A CZ  1 
ATOM   3642 N NH1 . ARG F  1 19 ? -44.71760 8.21330   10.24029  1.000 7.69755  ? 17  ARG A NH1 1 
ATOM   3643 N NH2 . ARG F  1 19 ? -46.32255 9.00315   8.81145   1.000 9.20781  ? 17  ARG A NH2 1 
ATOM   3644 N N   . VAL F  1 20 ? -41.46731 2.30007   10.35299  1.000 5.99631  ? 18  VAL A N   1 
ATOM   3645 C CA  . VAL F  1 20 ? -40.77969 1.03151   10.55607  1.000 6.74068  ? 18  VAL A CA  1 
ATOM   3646 C C   . VAL F  1 20 ? -41.57267 -0.03709  9.82397   1.000 5.50116  ? 18  VAL A C   1 
ATOM   3647 O O   . VAL F  1 20 ? -42.76803 -0.22034  10.09726  1.000 6.32705  ? 18  VAL A O   1 
ATOM   3648 C CB  . VAL F  1 20 ? -40.63871 0.68087   12.04480  1.000 6.70376  ? 18  VAL A CB  1 
ATOM   3649 C CG1 . VAL F  1 20 ? -39.93606 -0.66348  12.19905  1.000 8.14373  ? 18  VAL A CG1 1 
ATOM   3650 C CG2 . VAL F  1 20 ? -39.88601 1.76910   12.77478  1.000 8.38006  ? 18  VAL A CG2 1 
ATOM   3651 N N   . TYR F  1 21 ? -40.91710 -0.72085  8.88545   1.000 6.24646  ? 19  TYR A N   1 
ATOM   3652 C CA  . TYR F  1 21 ? -41.52104 -1.76135  8.05884   1.000 6.65434  ? 19  TYR A CA  1 
ATOM   3653 C C   . TYR F  1 21 ? -41.03578 -3.10806  8.56260   1.000 6.69726  ? 19  TYR A C   1 
ATOM   3654 O O   . TYR F  1 21 ? -39.84148 -3.26950  8.82981   1.000 7.44683  ? 19  TYR A O   1 
ATOM   3655 C CB  . TYR F  1 21 ? -41.13843 -1.56850  6.57303   1.000 6.36676  ? 19  TYR A CB  1 
ATOM   3656 C CG  . TYR F  1 21 ? -41.59837 -0.22018  6.11142   1.000 6.41469  ? 19  TYR A CG  1 
ATOM   3657 C CD1 . TYR F  1 21 ? -42.86337 -0.05015  5.57427   1.000 6.57007  ? 19  TYR A CD1 1 
ATOM   3658 C CD2 . TYR F  1 21 ? -40.81645 0.90270   6.31179   1.000 6.26860  ? 19  TYR A CD2 1 
ATOM   3659 C CE1 . TYR F  1 21 ? -43.32772 1.20244   5.22773   1.000 6.92278  ? 19  TYR A CE1 1 
ATOM   3660 C CE2 . TYR F  1 21 ? -41.26808 2.16308   5.96548   1.000 6.30557  ? 19  TYR A CE2 1 
ATOM   3661 C CZ  . TYR F  1 21 ? -42.52978 2.30779   5.43191   1.000 6.28896  ? 19  TYR A CZ  1 
ATOM   3662 O OH  . TYR F  1 21 ? -42.98700 3.56800   5.12038   1.000 7.30571  ? 19  TYR A OH  1 
ATOM   3663 N N   . THR F  1 22 ? -41.95471 -4.06046  8.72121   1.000 6.89209  ? 20  THR A N   1 
ATOM   3664 C CA  . THR F  1 22 ? -41.61615 -5.38977  9.21891   1.000 6.92828  ? 20  THR A CA  1 
ATOM   3665 C C   . THR F  1 22 ? -42.06845 -6.43757  8.21983   1.000 7.19590  ? 20  THR A C   1 
ATOM   3666 O O   . THR F  1 22 ? -43.25210 -6.48489  7.86981   1.000 7.70919  ? 20  THR A O   1 
ATOM   3667 C CB  . THR F  1 22 ? -42.29802 -5.65697  10.55783  1.000 7.84989  ? 20  THR A CB  1 
ATOM   3668 O OG1 . THR F  1 22 ? -41.84916 -4.69181  11.51025  1.000 8.50051  ? 20  THR A OG1 1 
ATOM   3669 C CG2 . THR F  1 22 ? -41.96463 -7.05078  11.07396  1.000 9.80604  ? 20  THR A CG2 1 
ATOM   3670 N N   . ALA F  1 23 ? -41.13492 -7.27940  7.78029   1.000 7.52538  ? 21  ALA A N   1 
ATOM   3671 C CA  . ALA F  1 23 ? -41.43807 -8.43570  6.94868   1.000 8.07156  ? 21  ALA A CA  1 
ATOM   3672 C C   . ALA F  1 23 ? -41.60584 -9.64810  7.85720   1.000 8.39814  ? 21  ALA A C   1 
ATOM   3673 O O   . ALA F  1 23 ? -40.69944 -9.98524  8.62677   1.000 9.89343  ? 21  ALA A O   1 
ATOM   3674 C CB  . ALA F  1 23 ? -40.31219 -8.67862  5.94680   1.000 9.60386  ? 21  ALA A CB  1 
ATOM   3675 N N   . ASN F  1 24 ? -42.76077 -10.30033 7.76664   1.000 9.72270  ? 22  ASN A N   1 
ATOM   3676 C CA  . ASN F  1 24 ? -43.09914 -11.42075 8.63881   1.000 10.27536 ? 22  ASN A CA  1 
ATOM   3677 C C   . ASN F  1 24 ? -43.99306 -12.36336 7.85073   1.000 11.89403 ? 22  ASN A C   1 
ATOM   3678 O O   . ASN F  1 24 ? -45.05649 -11.95197 7.38882   1.000 12.44932 ? 22  ASN A O   1 
ATOM   3679 C CB  . ASN F  1 24 ? -43.85010 -10.90171 9.86772   1.000 11.96140 ? 22  ASN A CB  1 
ATOM   3680 C CG  . ASN F  1 24 ? -44.18901 -12.00106 10.86460  1.000 16.02527 ? 22  ASN A CG  1 
ATOM   3681 O OD1 . ASN F  1 24 ? -43.61931 -13.08698 10.82392  1.000 17.11792 ? 22  ASN A OD1 1 
ATOM   3682 N ND2 . ASN F  1 24 ? -45.10492 -11.70758 11.78043  1.000 19.86447 ? 22  ASN A ND2 1 
ATOM   3683 N N   . ASN F  1 25 ? -43.57268 -13.62039 7.69624   1.000 17.64396 ? 23  ASN A N   1 
ATOM   3684 C CA  . ASN F  1 25 ? -44.40470 -14.63672 7.03948   1.000 18.55976 ? 23  ASN A CA  1 
ATOM   3685 C C   . ASN F  1 25 ? -44.84599 -14.19410 5.64524   1.000 16.83239 ? 23  ASN A C   1 
ATOM   3686 O O   . ASN F  1 25 ? -45.98602 -14.41363 5.23374   1.000 19.73438 ? 23  ASN A O   1 
ATOM   3687 C CB  . ASN F  1 25 ? -45.61859 -15.01777 7.89361   1.000 22.25687 ? 23  ASN A CB  1 
ATOM   3688 C CG  . ASN F  1 25 ? -45.23309 -15.63073 9.22370   1.000 37.30866 ? 23  ASN A CG  1 
ATOM   3689 O OD1 . ASN F  1 25 ? -44.23396 -16.34332 9.32676   1.000 43.66866 ? 23  ASN A OD1 1 
ATOM   3690 N ND2 . ASN F  1 25 ? -46.02946 -15.35887 10.25261  1.000 36.84916 ? 23  ASN A ND2 1 
ATOM   3691 N N   . GLY F  1 26 ? -43.94799 -13.52197 4.92895   1.000 14.66517 ? 24  GLY A N   1 
ATOM   3692 C CA  . GLY F  1 26 ? -44.20773 -13.12278 3.56244   1.000 15.05251 ? 24  GLY A CA  1 
ATOM   3693 C C   . GLY F  1 26 ? -45.00067 -11.84622 3.38202   1.000 12.67307 ? 24  GLY A C   1 
ATOM   3694 O O   . GLY F  1 26 ? -45.34085 -11.51130 2.24089   1.000 12.69277 ? 24  GLY A O   1 
ATOM   3695 N N   . LYS F  1 27 ? -45.31058 -11.12444 4.45712   1.000 10.96499 ? 25  LYS A N   1 
ATOM   3696 C CA  . LYS F  1 27 ? -46.05217 -9.87432  4.37240   1.000 11.04398 ? 25  LYS A CA  1 
ATOM   3697 C C   . LYS F  1 27 ? -45.28504 -8.76804  5.07833   1.000 9.30819  ? 25  LYS A C   1 
ATOM   3698 O O   . LYS F  1 27 ? -44.69236 -8.98934  6.13941   1.000 10.20834 ? 25  LYS A O   1 
ATOM   3699 C CB  . LYS F  1 27 ? -47.44291 -9.99103  5.00566   1.000 13.57440 ? 25  LYS A CB  1 
ATOM   3700 C CG  . LYS F  1 27 ? -48.44008 -10.79231 4.18836   1.000 18.24184 ? 25  LYS A CG  1 
ATOM   3701 C CD  . LYS F  1 27 ? -49.81880 -10.75489 4.83465   1.000 34.76555 ? 25  LYS A CD  1 
ATOM   3702 C CE  . LYS F  1 27 ? -50.76878 -11.74870 4.18265   1.000 50.08380 ? 25  LYS A CE  1 
ATOM   3703 N NZ  . LYS F  1 27 ? -52.10637 -11.74647 4.83906   1.000 43.92613 ? 25  LYS A NZ  1 
ATOM   3704 N N   . ILE F  1 28 ? -45.31565 -7.57385  4.49410   1.000 8.52818  ? 26  ILE A N   1 
ATOM   3705 C CA  . ILE F  1 28 ? -44.69960 -6.38937  5.08111   1.000 7.50040  ? 26  ILE A CA  1 
ATOM   3706 C C   . ILE F  1 28 ? -45.79690 -5.45425  5.55947   1.000 8.01242  ? 26  ILE A C   1 
ATOM   3707 O O   . ILE F  1 28 ? -46.71571 -5.11786  4.79876   1.000 9.32912  ? 26  ILE A O   1 
ATOM   3708 C CB  . ILE F  1 28 ? -43.78346 -5.66440  4.08372   1.000 8.17434  ? 26  ILE A CB  1 
ATOM   3709 C CG1 . ILE F  1 28 ? -42.67500 -6.58673  3.57922   1.000 9.20708  ? 26  ILE A CG1 1 
ATOM   3710 C CG2 . ILE F  1 28 ? -43.19393 -4.41258  4.72798   1.000 10.03981 ? 26  ILE A CG2 1 
ATOM   3711 C CD1 . ILE F  1 28 ? -41.98182 -6.05773  2.34567   1.000 10.21334 ? 26  ILE A CD1 1 
ATOM   3712 N N   . THR F  1 29 ? -45.68859 -5.02134  6.81032   1.000 6.89667  ? 27  THR A N   1 
ATOM   3713 C CA  . THR F  1 29 ? -46.59341 -4.04926  7.39817   1.000 8.21611  ? 27  THR A CA  1 
ATOM   3714 C C   . THR F  1 29 ? -45.78837 -2.88622  7.96531   1.000 6.52443  ? 27  THR A C   1 
ATOM   3715 O O   . THR F  1 29 ? -44.55392 -2.91922  8.00767   1.000 8.06805  ? 27  THR A O   1 
ATOM   3716 C CB  . THR F  1 29 ? -47.46728 -4.70642  8.47203   1.000 10.08450 ? 27  THR A CB  1 
ATOM   3717 O OG1 . THR F  1 29 ? -46.62969 -5.35462  9.43514   1.000 10.66805 ? 27  THR A OG1 1 
ATOM   3718 C CG2 . THR F  1 29 ? -48.40359 -5.73592  7.84706   1.000 10.86924 ? 27  THR A CG2 1 
ATOM   3719 N N   . GLU F  1 30 ? -46.49113 -1.84001  8.39239   1.000 6.80517  ? 28  GLU A N   1 
ATOM   3720 C CA  . GLU F  1 30 ? -45.87294 -0.55534  8.68727   1.000 6.57895  ? 28  GLU A CA  1 
ATOM   3721 C C   . GLU F  1 30 ? -46.39536 -0.00498  10.00303  1.000 6.42948  ? 28  GLU A C   1 
ATOM   3722 O O   . GLU F  1 30 ? -47.61038 0.00695   10.23560  1.000 7.29251  ? 28  GLU A O   1 
ATOM   3723 C CB  . GLU F  1 30 ? -46.21430 0.42769   7.56796   1.000 6.79684  ? 28  GLU A CB  1 
ATOM   3724 C CG  . GLU F  1 30 ? -45.68721 1.83362   7.73718   1.000 7.64409  ? 28  GLU A CG  1 
ATOM   3725 C CD  . GLU F  1 30 ? -46.27637 2.78814   6.70493   1.000 7.29344  ? 28  GLU A CD  1 
ATOM   3726 O OE1 . GLU F  1 30 ? -47.51181 2.72522   6.49205   1.000 7.76426  ? 28  GLU A OE1 1 
ATOM   3727 O OE2 . GLU F  1 30 ? -45.51680 3.60229   6.11671   1.000 7.25596  ? 28  GLU A OE2 1 
ATOM   3728 N N   . ARG F  1 31 ? -45.48204 0.46825   10.84618  1.000 6.46183  ? 29  ARG A N   1 
ATOM   3729 C CA  . ARG F  1 31 ? -45.82052 1.20598   12.05397  1.000 6.31198  ? 29  ARG A CA  1 
ATOM   3730 C C   . ARG F  1 31 ? -45.27489 2.62139   11.92757  1.000 6.21225  ? 29  ARG A C   1 
ATOM   3731 O O   . ARG F  1 31 ? -44.19472 2.82993   11.35408  1.000 7.59295  ? 29  ARG A O   1 
ATOM   3732 C CB  . ARG F  1 31 ? -45.27750 0.50254   13.29264  1.000 7.13466  ? 29  ARG A CB  1 
ATOM   3733 C CG  . ARG F  1 31 ? -45.91713 -0.85155  13.52245  1.000 7.76410  ? 29  ARG A CG  1 
ATOM   3734 C CD  . ARG F  1 31 ? -47.31351 -0.73169  14.12422  1.000 8.84211  ? 29  ARG A CD  1 
ATOM   3735 N NE  . ARG F  1 31 ? -47.25230 -0.42868  15.55245  1.000 7.47609  ? 29  ARG A NE  1 
ATOM   3736 C CZ  . ARG F  1 31 ? -48.29924 -0.09005  16.29685  1.000 8.54526  ? 29  ARG A CZ  1 
ATOM   3737 N NH1 . ARG F  1 31 ? -49.49782 0.08820   15.76510  1.000 9.13541  ? 29  ARG A NH1 1 
ATOM   3738 N NH2 . ARG F  1 31 ? -48.13524 0.08637   17.60616  1.000 8.57273  ? 29  ARG A NH2 1 
ATOM   3739 N N   . CYS F  1 32 ? -46.02441 3.58814   12.46029  1.000 6.25293  ? 30  CYS A N   1 
ATOM   3740 C CA  . CYS F  1 32 ? -45.78648 4.99965   12.20700  1.000 6.30596  ? 30  CYS A CA  1 
ATOM   3741 C C   . CYS F  1 32 ? -45.69842 5.76061   13.51454  1.000 6.04474  ? 30  CYS A C   1 
ATOM   3742 O O   . CYS F  1 32 ? -46.47077 5.50151   14.44100  1.000 6.64345  ? 30  CYS A O   1 
ATOM   3743 C CB  . CYS F  1 32 ? -46.96512 5.59787   11.43364  1.000 7.40259  ? 30  CYS A CB  1 
ATOM   3744 S SG  . CYS F  1 32 ? -47.41637 4.74250   9.94093   1.000 7.71248  ? 30  CYS A SG  1 
ATOM   3745 N N   . TRP F  1 33 ? -44.79292 6.73533   13.55827  1.000 6.14825  ? 31  TRP A N   1 
ATOM   3746 C CA  . TRP F  1 33 ? -44.65712 7.67829   14.65930  1.000 6.94828  ? 31  TRP A CA  1 
ATOM   3747 C C   . TRP F  1 33 ? -44.59991 9.07219   14.06031  1.000 6.39010  ? 31  TRP A C   1 
ATOM   3748 O O   . TRP F  1 33 ? -43.78785 9.32249   13.16636  1.000 6.92627  ? 31  TRP A O   1 
ATOM   3749 C CB  . TRP F  1 33 ? -43.34538 7.42010   15.40779  1.000 7.20135  ? 31  TRP A CB  1 
ATOM   3750 C CG  . TRP F  1 33 ? -42.98099 8.43124   16.46780  1.000 6.89673  ? 31  TRP A CG  1 
ATOM   3751 C CD1 . TRP F  1 33 ? -42.20295 9.54418   16.31689  1.000 7.24752  ? 31  TRP A CD1 1 
ATOM   3752 C CD2 . TRP F  1 33 ? -43.34716 8.38536   17.85011  1.000 7.14091  ? 31  TRP A CD2 1 
ATOM   3753 N NE1 . TRP F  1 33 ? -42.07790 10.20238  17.51718  1.000 7.98785  ? 31  TRP A NE1 1 
ATOM   3754 C CE2 . TRP F  1 33 ? -42.76401 9.50339   18.47631  1.000 7.55745  ? 31  TRP A CE2 1 
ATOM   3755 C CE3 . TRP F  1 33 ? -44.08441 7.48623   18.62586  1.000 7.73597  ? 31  TRP A CE3 1 
ATOM   3756 C CZ2 . TRP F  1 33 ? -42.92339 9.76178   19.83891  1.000 8.37312  ? 31  TRP A CZ2 1 
ATOM   3757 C CZ3 . TRP F  1 33 ? -44.23309 7.74087   19.97337  1.000 8.02048  ? 31  TRP A CZ3 1 
ATOM   3758 C CH2 . TRP F  1 33 ? -43.66116 8.87059   20.56405  1.000 8.01616  ? 31  TRP A CH2 1 
ATOM   3759 N N   . ASP F  1 34 ? -45.45168 9.97738   14.54762  1.000 7.37173  ? 32  ASP A N   1 
ATOM   3760 C CA  . ASP F  1 34 ? -45.38401 11.39286  14.19881  1.000 8.06215  ? 32  ASP A CA  1 
ATOM   3761 C C   . ASP F  1 34 ? -45.31846 12.24374  15.46133  1.000 8.55915  ? 32  ASP A C   1 
ATOM   3762 O O   . ASP F  1 34 ? -45.86164 13.35452  15.50378  1.000 10.56510 ? 32  ASP A O   1 
ATOM   3763 C CB  . ASP F  1 34 ? -46.55659 11.84429  13.32597  1.000 8.94739  ? 32  ASP A CB  1 
ATOM   3764 C CG  . ASP F  1 34 ? -46.73781 11.00512  12.07958  1.000 9.73896  ? 32  ASP A CG  1 
ATOM   3765 O OD1 . ASP F  1 34 ? -45.77353 10.80109  11.30862  1.000 9.71139  ? 32  ASP A OD1 1 
ATOM   3766 O OD2 . ASP F  1 34 ? -47.88497 10.56053  11.85428  1.000 14.45331 ? 32  ASP A OD2 1 
ATOM   3767 N N   . GLY F  1 35 ? -44.68482 11.72685  16.51028  1.000 7.56009  ? 33  GLY A N   1 
ATOM   3768 C CA  . GLY F  1 35 ? -44.46092 12.48311  17.72134  1.000 8.60641  ? 33  GLY A CA  1 
ATOM   3769 C C   . GLY F  1 35 ? -45.45899 12.25591  18.83307  1.000 9.01806  ? 33  GLY A C   1 
ATOM   3770 O O   . GLY F  1 35 ? -45.28269 12.82504  19.92112  1.000 9.14749  ? 33  GLY A O   1 
ATOM   3771 N N   . LYS F  1 36 ? -46.49510 11.44268  18.60672  1.000 8.01473  ? 34  LYS A N   1 
ATOM   3772 C CA  . LYS F  1 36 ? -47.61921 11.38505  19.53220  1.000 8.18328  ? 34  LYS A CA  1 
ATOM   3773 C C   . LYS F  1 36 ? -48.08261 9.95874   19.79869  1.000 8.08007  ? 34  LYS A C   1 
ATOM   3774 O O   . LYS F  1 36 ? -49.21740 9.76588   20.25291  1.000 11.96036 ? 34  LYS A O   1 
ATOM   3775 C CB  . LYS F  1 36 ? -48.79107 12.22018  19.00031  1.000 10.01610 ? 34  LYS A CB  1 
ATOM   3776 C CG  . LYS F  1 36 ? -48.43655 13.68399  18.81663  1.000 14.99305 ? 34  LYS A CG  1 
ATOM   3777 C CD  . LYS F  1 36 ? -49.65620 14.55383  18.60515  1.000 24.23662 ? 34  LYS A CD  1 
ATOM   3778 C CE  . LYS F  1 36 ? -49.26182 16.01568  18.71393  1.000 42.86621 ? 34  LYS A CE  1 
ATOM   3779 N NZ  . LYS F  1 36 ? -48.06289 16.30428  17.88194  1.000 50.24980 ? 34  LYS A NZ  1 
ATOM   3780 N N   . GLY F  1 37 ? -47.25041 8.95806   19.53967  1.000 7.94017  ? 35  GLY A N   1 
ATOM   3781 C CA  . GLY F  1 37 ? -47.63574 7.57584   19.72572  1.000 8.34564  ? 35  GLY A CA  1 
ATOM   3782 C C   . GLY F  1 37 ? -47.50322 6.78379   18.44038  1.000 7.49996  ? 35  GLY A C   1 
ATOM   3783 O O   . GLY F  1 37 ? -47.59669 7.34944   17.34668  1.000 9.19341  ? 35  GLY A O   1 
ATOM   3784 N N   . TRP F  1 38 ? -47.29471 5.47863   18.54787  1.000 6.86231  ? 36  TRP A N   1 
ATOM   3785 C CA  . TRP F  1 38 ? -47.18625 4.62356   17.37778  1.000 6.59984  ? 36  TRP A CA  1 
ATOM   3786 C C   . TRP F  1 38 ? -48.56449 4.17398   16.91206  1.000 6.35321  ? 36  TRP A C   1 
ATOM   3787 O O   . TRP F  1 38 ? -49.47615 3.95957   17.71639  1.000 8.74782  ? 36  TRP A O   1 
ATOM   3788 C CB  . TRP F  1 38 ? -46.32098 3.40650   17.69958  1.000 7.51057  ? 36  TRP A CB  1 
ATOM   3789 C CG  . TRP F  1 38 ? -44.87896 3.76076   17.86971  1.000 6.96018  ? 36  TRP A CG  1 
ATOM   3790 C CD1 . TRP F  1 38 ? -44.24567 4.12364   19.02013  1.000 7.42828  ? 36  TRP A CD1 1 
ATOM   3791 C CD2 . TRP F  1 38 ? -43.89982 3.82571   16.83474  1.000 7.40625  ? 36  TRP A CD2 1 
ATOM   3792 N NE1 . TRP F  1 38 ? -42.92591 4.40005   18.76500  1.000 7.67795  ? 36  TRP A NE1 1 
ATOM   3793 C CE2 . TRP F  1 38 ? -42.68614 4.22190   17.42975  1.000 7.29684  ? 36  TRP A CE2 1 
ATOM   3794 C CE3 . TRP F  1 38 ? -43.92953 3.57749   15.46212  1.000 7.20329  ? 36  TRP A CE3 1 
ATOM   3795 C CZ2 . TRP F  1 38 ? -41.50988 4.37457   16.69660  1.000 8.06349  ? 36  TRP A CZ2 1 
ATOM   3796 C CZ3 . TRP F  1 38 ? -42.76438 3.73322   14.73162  1.000 7.29719  ? 36  TRP A CZ3 1 
ATOM   3797 C CH2 . TRP F  1 38 ? -41.56687 4.13028   15.35003  1.000 7.49340  ? 36  TRP A CH2 1 
ATOM   3798 N N   . TYR F  1 39 ? -48.70622 4.00993   15.60120  1.000 6.82700  ? 37  TYR A N   1 
ATOM   3799 C CA  . TYR F  1 39 ? -49.96233 3.53474   15.04041  1.000 6.53812  ? 37  TYR A CA  1 
ATOM   3800 C C   . TYR F  1 39 ? -49.67193 2.78974   13.74312  1.000 7.24880  ? 37  TYR A C   1 
ATOM   3801 O O   . TYR F  1 39 ? -48.58610 2.90257   13.16420  1.000 8.16537  ? 37  TYR A O   1 
ATOM   3802 C CB  . TYR F  1 39 ? -50.97159 4.67817   14.84587  1.000 8.29809  ? 37  TYR A CB  1 
ATOM   3803 C CG  . TYR F  1 39 ? -50.51225 5.73606   13.86872  1.000 8.18378  ? 37  TYR A CG  1 
ATOM   3804 C CD1 . TYR F  1 39 ? -49.67590 6.76799   14.26977  1.000 8.86602  ? 37  TYR A CD1 1 
ATOM   3805 C CD2 . TYR F  1 39 ? -50.90965 5.69258   12.54149  1.000 9.18604  ? 37  TYR A CD2 1 
ATOM   3806 C CE1 . TYR F  1 39 ? -49.24600 7.72256   13.37942  1.000 9.65793  ? 37  TYR A CE1 1 
ATOM   3807 C CE2 . TYR F  1 39 ? -50.49019 6.63803   11.64146  1.000 11.23872 ? 37  TYR A CE2 1 
ATOM   3808 C CZ  . TYR F  1 39 ? -49.65739 7.65136   12.05804  1.000 9.69212  ? 37  TYR A CZ  1 
ATOM   3809 O OH  . TYR F  1 39 ? -49.23851 8.58790   11.13807  1.000 12.66864 ? 37  TYR A OH  1 
ATOM   3810 N N   . THR F  1 40 ? -50.64945 2.02134   13.28436  1.000 7.08688  ? 38  THR A N   1 
ATOM   3811 C CA  . THR F  1 40 ? -50.46263 1.19641   12.10066  1.000 6.57913  ? 38  THR A CA  1 
ATOM   3812 C C   . THR F  1 40 ? -50.72850 1.99337   10.83315  1.000 6.77332  ? 38  THR A C   1 
ATOM   3813 O O   . THR F  1 40 ? -51.75263 2.68033   10.71606  1.000 7.65559  ? 38  THR A O   1 
ATOM   3814 C CB  . THR F  1 40 ? -51.34293 -0.04162  12.20211  1.000 8.85602  ? 38  THR A CB  1 
ATOM   3815 O OG1 . THR F  1 40 ? -50.85768 -0.81753  13.30257  1.000 10.05213 ? 38  THR A OG1 1 
ATOM   3816 C CG2 . THR F  1 40 ? -51.30553 -0.86847  10.91774  1.000 9.28888  ? 38  THR A CG2 1 
ATOM   3817 N N   . GLY F  1 41 ? -49.79246 1.89772   9.88428   1.000 7.55645  ? 39  GLY A N   1 
ATOM   3818 C CA  . GLY F  1 41 ? -49.91264 2.60825   8.63315   1.000 8.43118  ? 39  GLY A CA  1 
ATOM   3819 C C   . GLY F  1 41 ? -50.62656 1.80971   7.56780   1.000 7.48801  ? 39  GLY A C   1 
ATOM   3820 O O   . GLY F  1 41 ? -50.95479 0.63715   7.72639   1.000 7.73597  ? 39  GLY A O   1 
ATOM   3821 N N   . ALA F  1 42 ? -50.85498 2.48247   6.44838   1.000 7.44665  ? 40  ALA A N   1 
ATOM   3822 C CA  . ALA F  1 42 ? -51.57289 1.87717   5.33977   1.000 7.88377  ? 40  ALA A CA  1 
ATOM   3823 C C   . ALA F  1 42 ? -50.73603 0.88584   4.53818   1.000 8.77028  ? 40  ALA A C   1 
ATOM   3824 O O   . ALA F  1 42 ? -51.31348 0.08732   3.78783   1.000 10.12909 ? 40  ALA A O   1 
ATOM   3825 C CB  . ALA F  1 42 ? -52.12429 2.96863   4.42141   1.000 10.08288 ? 40  ALA A CB  1 
ATOM   3826 N N   . PHE F  1 43 ? -49.40549 0.90880   4.65065   1.000 7.89572  ? 41  PHE A N   1 
ATOM   3827 C CA  . PHE F  1 43 ? -48.59631 0.03593   3.80830   1.000 8.39306  ? 41  PHE A CA  1 
ATOM   3828 C C   . PHE F  1 43 ? -48.79827 -1.42568  4.18897   1.000 8.08724  ? 41  PHE A C   1 
ATOM   3829 O O   . PHE F  1 43 ? -48.53832 -1.82100  5.32934   1.000 9.35108  ? 41  PHE A O   1 
ATOM   3830 C CB  . PHE F  1 43 ? -47.11946 0.37509   3.91461   1.000 8.59614  ? 41  PHE A CB  1 
ATOM   3831 C CG  . PHE F  1 43 ? -46.28745 -0.42470  2.96368   1.000 8.53204  ? 41  PHE A CG  1 
ATOM   3832 C CD1 . PHE F  1 43 ? -46.18576 -0.03916  1.63978   1.000 12.66795 ? 41  PHE A CD1 1 
ATOM   3833 C CD2 . PHE F  1 43 ? -45.66804 -1.59683  3.36061   1.000 9.67442  ? 41  PHE A CD2 1 
ATOM   3834 C CE1 . PHE F  1 43 ? -45.44735 -0.77960  0.73753   1.000 16.74748 ? 41  PHE A CE1 1 
ATOM   3835 C CE2 . PHE F  1 43 ? -44.92746 -2.34704  2.45483   1.000 10.00264 ? 41  PHE A CE2 1 
ATOM   3836 C CZ  . PHE F  1 43 ? -44.81696 -1.93306  1.14336   1.000 10.78688 ? 41  PHE A CZ  1 
ATOM   3837 N N   . ASN F  1 44 ? -49.18941 -2.24599  3.21285   1.000 10.28146 ? 42  ASN A N   1 
ATOM   3838 C CA  . ASN F  1 44 ? -49.36261 -3.67789  3.44977   1.000 10.26991 ? 42  ASN A CA  1 
ATOM   3839 C C   . ASN F  1 44 ? -49.18723 -4.36622  2.10030   1.000 11.54208 ? 42  ASN A C   1 
ATOM   3840 O O   . ASN F  1 44 ? -50.10168 -4.34959  1.27090   1.000 15.23375 ? 42  ASN A O   1 
ATOM   3841 C CB  . ASN F  1 44 ? -50.73632 -3.95697  4.04832   1.000 16.25920 ? 42  ASN A CB  1 
ATOM   3842 C CG  . ASN F  1 44 ? -50.91048 -5.40319  4.48558   1.000 26.71796 ? 42  ASN A CG  1 
ATOM   3843 O OD1 . ASN F  1 44 ? -50.38968 -6.32667  3.86143   1.000 31.34958 ? 42  ASN A OD1 1 
ATOM   3844 N ND2 . ASN F  1 44 ? -51.65218 -5.60359  5.56784   1.000 34.83771 ? 42  ASN A ND2 1 
ATOM   3845 N N   . GLU F  1 45 ? -48.02304 -4.95900  1.88432   1.000 9.88585  ? 43  GLU A N   1 
ATOM   3846 C CA  . GLU F  1 45 ? -47.69661 -5.56096  0.60264   1.000 10.78168 ? 43  GLU A CA  1 
ATOM   3847 C C   . GLU F  1 45 ? -46.86612 -6.81084  0.83629   1.000 8.96233  ? 43  GLU A C   1 
ATOM   3848 O O   . GLU F  1 45 ? -46.20676 -6.94404  1.87305   1.000 10.03558 ? 43  GLU A O   1 
ATOM   3849 C CB  . GLU F  1 45 ? -46.92551 -4.58260  -0.30004  1.000 13.45247 ? 43  GLU A CB  1 
ATOM   3850 C CG  . GLU F  1 45 ? -47.68769 -3.30774  -0.67977  1.000 18.28814 ? 43  GLU A CG  1 
ATOM   3851 C CD  . GLU F  1 45 ? -48.98438 -3.56606  -1.44042  1.000 22.96952 ? 43  GLU A CD  1 
ATOM   3852 O OE1 . GLU F  1 45 ? -49.16892 -4.67107  -1.99612  1.000 22.99062 ? 43  GLU A OE1 1 
ATOM   3853 O OE2 . GLU F  1 45 ? -49.83403 -2.65078  -1.47958  1.000 30.22229 ? 43  GLU A OE2 1 
ATOM   3854 N N   . PRO F  1 46 ? -46.85926 -7.73966  -0.11926  1.000 10.22721 ? 44  PRO A N   1 
ATOM   3855 C CA  . PRO F  1 46 ? -46.07341 -8.96427  0.05290   1.000 9.92733  ? 44  PRO A CA  1 
ATOM   3856 C C   . PRO F  1 46 ? -44.57905 -8.68716  0.04657   1.000 9.04059  ? 44  PRO A C   1 
ATOM   3857 O O   . PRO F  1 46 ? -44.07628 -7.82165  -0.67481  1.000 11.05346 ? 44  PRO A O   1 
ATOM   3858 C CB  . PRO F  1 46 ? -46.46406 -9.81495  -1.16300  1.000 12.65401 ? 44  PRO A CB  1 
ATOM   3859 C CG  . PRO F  1 46 ? -47.73087 -9.23356  -1.67742  1.000 15.60589 ? 44  PRO A CG  1 
ATOM   3860 C CD  . PRO F  1 46 ? -47.70084 -7.77942  -1.32859  1.000 10.67987 ? 44  PRO A CD  1 
ATOM   3861 N N   . GLY F  1 47 ? -43.86648 -9.46339  0.84789   1.000 10.16095 ? 45  GLY A N   1 
ATOM   3862 C CA  . GLY F  1 47 ? -42.42475 -9.41072  0.84640   1.000 10.25376 ? 45  GLY A CA  1 
ATOM   3863 C C   . GLY F  1 47 ? -41.83572 -10.24932 1.95143   1.000 9.17632  ? 45  GLY A C   1 
ATOM   3864 O O   . GLY F  1 47 ? -42.35595 -10.29047 3.07083   1.000 10.94210 ? 45  GLY A O   1 
ATOM   3865 N N   . ASP F  1 48 ? -40.74583 -10.94017 1.63087   1.000 10.13818 ? 46  ASP A N   1 
ATOM   3866 C CA  . ASP F  1 48 ? -39.94796 -11.63619 2.62666   1.000 10.84834 ? 46  ASP A CA  1 
ATOM   3867 C C   . ASP F  1 48 ? -38.82960 -10.76547 3.17774   1.000 10.61983 ? 46  ASP A C   1 
ATOM   3868 O O   . ASP F  1 48 ? -38.32601 -11.04014 4.27117   1.000 12.61631 ? 46  ASP A O   1 
ATOM   3869 C CB  . ASP F  1 48 ? -39.30570 -12.87758 1.99939   1.000 13.89364 ? 46  ASP A CB  1 
ATOM   3870 C CG  . ASP F  1 48 ? -40.32443 -13.92621 1.59367   1.000 16.60312 ? 46  ASP A CG  1 
ATOM   3871 O OD1 . ASP F  1 48 ? -41.33846 -14.07710 2.30205   1.000 19.04678 ? 46  ASP A OD1 1 
ATOM   3872 O OD2 . ASP F  1 48 ? -40.09777 -14.60949 0.57461   1.000 20.47749 ? 46  ASP A OD2 1 
ATOM   3873 N N   . ASN F  1 49 ? -38.42388 -9.73870  2.43478   1.000 10.11280 ? 47  ASN A N   1 
ATOM   3874 C CA  . ASN F  1 49 ? -37.33725 -8.84991  2.81579   1.000 8.46159  ? 47  ASN A CA  1 
ATOM   3875 C C   . ASN F  1 49 ? -37.73519 -7.43094  2.45469   1.000 7.97498  ? 47  ASN A C   1 
ATOM   3876 O O   . ASN F  1 49 ? -38.42732 -7.21275  1.46211   1.000 9.06102  ? 47  ASN A O   1 
ATOM   3877 C CB  . ASN F  1 49 ? -36.04441 -9.19647  2.06996   1.000 10.75023 ? 47  ASN A CB  1 
ATOM   3878 C CG  . ASN F  1 49 ? -34.94375 -8.18225  2.31508   1.000 11.53323 ? 47  ASN A CG  1 
ATOM   3879 O OD1 . ASN F  1 49 ? -34.72980 -7.25100  1.52439   1.000 11.52641 ? 47  ASN A OD1 1 
ATOM   3880 N ND2 . ASN F  1 49 ? -34.25103 -8.34279  3.43204   1.000 13.90992 ? 47  ASN A ND2 1 
ATOM   3881 N N   . VAL F  1 50 ? -37.29962 -6.46712  3.26946   1.000 8.39850  ? 48  VAL A N   1 
ATOM   3882 C CA  . VAL F  1 50 ? -37.68152 -5.07231  3.07498   1.000 8.03247  ? 48  VAL A CA  1 
ATOM   3883 C C   . VAL F  1 50 ? -36.48692 -4.15846  3.32799   1.000 7.34556  ? 48  VAL A C   1 
ATOM   3884 O O   . VAL F  1 50 ? -35.71294 -4.36512  4.26690   1.000 8.44297  ? 48  VAL A O   1 
ATOM   3885 C CB  . VAL F  1 50 ? -38.90724 -4.68320  3.94565   1.000 7.76543  ? 48  VAL A CB  1 
ATOM   3886 C CG1 . VAL F  1 50 ? -38.62230 -4.82103  5.44417   1.000 9.41222  ? 48  VAL A CG1 1 
ATOM   3887 C CG2 . VAL F  1 50 ? -39.39114 -3.28322  3.60671   1.000 9.84174  ? 48  VAL A CG2 1 
ATOM   3888 N N   . SER F  1 51 ? -36.34739 -3.13861  2.48611   1.000 7.60240  ? 49  SER A N   1 
ATOM   3889 C CA  . SER F  1 51 ? -35.51488 -1.98238  2.78201   1.000 6.46332  ? 49  SER A CA  1 
ATOM   3890 C C   . SER F  1 51 ? -36.31276 -0.73051  2.45353   1.000 6.43341  ? 49  SER A C   1 
ATOM   3891 O O   . SER F  1 51 ? -37.36322 -0.79442  1.80349   1.000 7.01370  ? 49  SER A O   1 
ATOM   3892 C CB  . SER F  1 51 ? -34.18850 -2.00134  2.00637   1.000 7.21290  ? 49  SER A CB  1 
ATOM   3893 O OG  . SER F  1 51 ? -34.39318 -1.82040  0.61799   1.000 7.66654  ? 49  SER A OG  1 
ATOM   3894 N N   . VAL F  1 52 ? -35.82567 0.42258   2.91327   1.000 6.31872  ? 50  VAL A N   1 
ATOM   3895 C CA  . VAL F  1 52 ? -36.56959 1.66044   2.72427   1.000 6.90838  ? 50  VAL A CA  1 
ATOM   3896 C C   . VAL F  1 52 ? -35.60699 2.83434   2.64331   1.000 6.12129  ? 50  VAL A C   1 
ATOM   3897 O O   . VAL F  1 52 ? -34.53509 2.83052   3.25509   1.000 7.29363  ? 50  VAL A O   1 
ATOM   3898 C CB  . VAL F  1 52 ? -37.61725 1.86488   3.84762   1.000 7.37916  ? 50  VAL A CB  1 
ATOM   3899 C CG1 . VAL F  1 52 ? -36.94545 2.04444   5.21137   1.000 7.95259  ? 50  VAL A CG1 1 
ATOM   3900 C CG2 . VAL F  1 52 ? -38.54662 3.03671   3.54273   1.000 8.24286  ? 50  VAL A CG2 1 
ATOM   3901 N N   . THR F  1 53 ? -36.01167 3.85888   1.89946   1.000 6.37211  ? 51  THR A N   1 
ATOM   3902 C CA  . THR F  1 53 ? -35.37267 5.16232   1.96273   1.000 7.43686  ? 51  THR A CA  1 
ATOM   3903 C C   . THR F  1 53 ? -36.44462 6.22789   1.77689   1.000 6.89391  ? 51  THR A C   1 
ATOM   3904 O O   . THR F  1 53 ? -37.54845 5.94114   1.30520   1.000 7.80765  ? 51  THR A O   1 
ATOM   3905 C CB  . THR F  1 53 ? -34.24525 5.27831   0.92358   1.000 7.67850  ? 51  THR A CB  1 
ATOM   3906 O OG1 . THR F  1 53 ? -33.46574 6.45329   1.17680   1.000 8.48442  ? 51  THR A OG1 1 
ATOM   3907 C CG2 . THR F  1 53 ? -34.79651 5.32505   -0.49837  1.000 9.18048  ? 51  THR A CG2 1 
ATOM   3908 N N   . SER F  1 54 ? -36.13105 7.46261   2.16884   1.000 6.88358  ? 52  SER A N   1 
ATOM   3909 C CA  . SER F  1 54 ? -37.08947 8.55034   2.00585   1.000 7.75550  ? 52  SER A CA  1 
ATOM   3910 C C   . SER F  1 54 ? -36.34363 9.86078   1.84795   1.000 6.78398  ? 52  SER A C   1 
ATOM   3911 O O   . SER F  1 54 ? -35.19570 9.98526   2.26354   1.000 7.57265  ? 52  SER A O   1 
ATOM   3912 C CB  . SER F  1 54 ? -38.06832 8.64097   3.18467   1.000 7.31736  ? 52  SER A CB  1 
ATOM   3913 O OG  . SER F  1 54 ? -37.40969 9.02375   4.38645   1.000 7.78929  ? 52  SER A OG  1 
ATOM   3914 N N   . TRP F  1 55 ? -37.01924 10.84636  1.25989   1.000 7.04890  ? 53  TRP A N   1 
ATOM   3915 C CA  . TRP F  1 55 ? -36.44296 12.16792  1.08674   1.000 8.38514  ? 53  TRP A CA  1 
ATOM   3916 C C   . TRP F  1 55 ? -37.56228 13.19209  1.12246   1.000 8.03845  ? 53  TRP A C   1 
ATOM   3917 O O   . TRP F  1 55 ? -38.70804 12.89875  0.77171   1.000 8.98435  ? 53  TRP A O   1 
ATOM   3918 C CB  . TRP F  1 55 ? -35.65986 12.30058  -0.23022  1.000 9.57293  ? 53  TRP A CB  1 
ATOM   3919 C CG  . TRP F  1 55 ? -36.50682 12.15056  -1.46504  1.000 8.90665  ? 53  TRP A CG  1 
ATOM   3920 C CD1 . TRP F  1 55 ? -37.09627 13.15383  -2.18718  1.000 10.14176 ? 53  TRP A CD1 1 
ATOM   3921 C CD2 . TRP F  1 55 ? -36.87928 10.92436  -2.10806  1.000 8.86837  ? 53  TRP A CD2 1 
ATOM   3922 N NE1 . TRP F  1 55 ? -37.80403 12.62431  -3.23991  1.000 9.81385  ? 53  TRP A NE1 1 
ATOM   3923 C CE2 . TRP F  1 55 ? -37.68614 11.25999  -3.21490  1.000 8.94268  ? 53  TRP A CE2 1 
ATOM   3924 C CE3 . TRP F  1 55 ? -36.60055 9.57443   -1.85971  1.000 8.53087  ? 53  TRP A CE3 1 
ATOM   3925 C CZ2 . TRP F  1 55 ? -38.22335 10.29673  -4.06662  1.000 9.11837  ? 53  TRP A CZ2 1 
ATOM   3926 C CZ3 . TRP F  1 55 ? -37.12461 8.62096   -2.71873  1.000 9.20633  ? 53  TRP A CZ3 1 
ATOM   3927 C CH2 . TRP F  1 55 ? -37.93202 8.98776   -3.80582  1.000 9.46826  ? 53  TRP A CH2 1 
ATOM   3928 N N   . LEU F  1 56 ? -37.20535 14.40398  1.53423   1.000 9.63173  ? 54  LEU A N   1 
ATOM   3929 C CA  . LEU F  1 56 ? -38.12295 15.53026  1.54954   1.000 9.66452  ? 54  LEU A CA  1 
ATOM   3930 C C   . LEU F  1 56 ? -37.91450 16.38876  0.31182   1.000 10.29286 ? 54  LEU A C   1 
ATOM   3931 O O   . LEU F  1 56 ? -36.78406 16.60143  -0.13473  1.000 12.36084 ? 54  LEU A O   1 
ATOM   3932 C CB  . LEU F  1 56 ? -37.89073 16.39028  2.79020   1.000 11.24145 ? 54  LEU A CB  1 
ATOM   3933 C CG  . LEU F  1 56 ? -38.39290 15.80511  4.10583   1.000 12.61084 ? 54  LEU A CG  1 
ATOM   3934 C CD1 . LEU F  1 56 ? -37.76589 16.54842  5.26943   1.000 13.66408 ? 54  LEU A CD1 1 
ATOM   3935 C CD2 . LEU F  1 56 ? -39.90604 15.88209  4.17259   1.000 13.97939 ? 54  LEU A CD2 1 
ATOM   3936 N N   . VAL F  1 57 ? -39.01430 16.87088  -0.24518  1.000 10.53062 ? 55  VAL A N   1 
ATOM   3937 C CA  . VAL F  1 57 ? -38.99660 17.97582  -1.19381  1.000 11.53702 ? 55  VAL A CA  1 
ATOM   3938 C C   . VAL F  1 57 ? -39.77529 19.07995  -0.49593  1.000 12.55137 ? 55  VAL A C   1 
ATOM   3939 O O   . VAL F  1 57 ? -41.00227 19.00121  -0.37735  1.000 12.88058 ? 55  VAL A O   1 
ATOM   3940 C CB  . VAL F  1 57 ? -39.61711 17.60826  -2.54575  1.000 12.89810 ? 55  VAL A CB  1 
ATOM   3941 C CG1 . VAL F  1 57 ? -39.54179 18.79205  -3.49992  1.000 17.00551 ? 55  VAL A CG1 1 
ATOM   3942 C CG2 . VAL F  1 57 ? -38.91014 16.39791  -3.14628  1.000 15.04186 ? 55  VAL A CG2 1 
ATOM   3943 N N   . GLY F  1 58 ? -39.06844 20.07718  0.01329   1.000 14.90867 ? 56  GLY A N   1 
ATOM   3944 C CA  . GLY F  1 58 ? -39.71786 21.04812  0.87639   1.000 15.47607 ? 56  GLY A CA  1 
ATOM   3945 C C   . GLY F  1 58 ? -40.28630 20.33808  2.08951   1.000 16.14710 ? 56  GLY A C   1 
ATOM   3946 O O   . GLY F  1 58 ? -39.56847 19.65227  2.82718   1.000 17.32395 ? 56  GLY A O   1 
ATOM   3947 N N   . SER F  1 59 ? -41.59690 20.46685  2.28853   1.000 15.10933 ? 57  SER A N   1 
ATOM   3948 C CA  . SER F  1 59 ? -42.28308 19.83237  3.40593   1.000 16.22809 ? 57  SER A CA  1 
ATOM   3949 C C   . SER F  1 59 ? -42.83428 18.45417  3.06839   1.000 16.80172 ? 57  SER A C   1 
ATOM   3950 O O   . SER F  1 59 ? -43.31792 17.76266  3.97134   1.000 16.81600 ? 57  SER A O   1 
ATOM   3951 C CB  . SER F  1 59 ? -43.43632 20.72083  3.89748   1.000 15.82743 ? 57  SER A CB  1 
ATOM   3952 O OG  . SER F  1 59 ? -42.95183 21.95094  4.40491   1.000 23.41602 ? 57  SER A OG  1 
ATOM   3953 N N   . ALA F  1 60 ? -42.77232 18.04016  1.80691   1.000 13.34483 ? 58  ALA A N   1 
ATOM   3954 C CA  . ALA F  1 60 ? -43.44397 16.83424  1.34151   1.000 13.58942 ? 58  ALA A CA  1 
ATOM   3955 C C   . ALA F  1 60 ? -42.50496 15.63360  1.40170   1.000 11.21354 ? 58  ALA A C   1 
ATOM   3956 O O   . ALA F  1 60 ? -41.39830 15.67544  0.85541   1.000 12.22761 ? 58  ALA A O   1 
ATOM   3957 C CB  . ALA F  1 60 ? -43.92596 17.03511  -0.09446  1.000 17.12885 ? 58  ALA A CB  1 
ATOM   3958 N N   . ILE F  1 61 ? -42.96092 14.55290  2.04055   1.000 10.89958 ? 59  ILE A N   1 
ATOM   3959 C CA  . ILE F  1 61 ? -42.15908 13.34132  2.17071   1.000 9.22527  ? 59  ILE A CA  1 
ATOM   3960 C C   . ILE F  1 61 ? -42.42241 12.42076  0.99159   1.000 9.05341  ? 59  ILE A C   1 
ATOM   3961 O O   . ILE F  1 61 ? -43.54162 12.32428  0.47248   1.000 10.23401 ? 59  ILE A O   1 
ATOM   3962 C CB  . ILE F  1 61 ? -42.43143 12.62714  3.51079   1.000 9.97586  ? 59  ILE A CB  1 
ATOM   3963 C CG1 . ILE F  1 61 ? -41.41842 11.50325  3.75316   1.000 10.24131 ? 59  ILE A CG1 1 
ATOM   3964 C CG2 . ILE F  1 61 ? -43.85632 12.08176  3.56051   1.000 12.15745 ? 59  ILE A CG2 1 
ATOM   3965 C CD1 . ILE F  1 61 ? -39.99403 11.97977  3.89448   1.000 9.70391  ? 59  ILE A CD1 1 
ATOM   3966 N N   . HIS F  1 62 ? -41.36659 11.73290  0.57450   1.000 8.55665  ? 60  HIS A N   1 
ATOM   3967 C CA  . HIS F  1 62 ? -41.42586 10.71677  -0.46371  1.000 7.98492  ? 60  HIS A CA  1 
ATOM   3968 C C   . HIS F  1 62 ? -40.72547 9.49230   0.08999   1.000 8.07329  ? 60  HIS A C   1 
ATOM   3969 O O   . HIS F  1 62 ? -39.58271 9.59095   0.53905   1.000 8.98975  ? 60  HIS A O   1 
ATOM   3970 C CB  . HIS F  1 62 ? -40.71561 11.23333  -1.71083  1.000 8.18357  ? 60  HIS A CB  1 
ATOM   3971 C CG  . HIS F  1 62 ? -41.35123 12.46777  -2.25368  1.000 9.46135  ? 60  HIS A CG  1 
ATOM   3972 N ND1 . HIS F  1 62 ? -42.35215 12.42587  -3.19869  1.000 11.60936 ? 60  HIS A ND1 1 
ATOM   3973 C CD2 . HIS F  1 62 ? -41.20235 13.77106  -1.91778  1.000 11.33854 ? 60  HIS A CD2 1 
ATOM   3974 C CE1 . HIS F  1 62 ? -42.76045 13.65639  -3.45705  1.000 13.53041 ? 60  HIS A CE1 1 
ATOM   3975 N NE2 . HIS F  1 62 ? -42.08211 14.49053  -2.68988  1.000 12.17792 ? 60  HIS A NE2 1 
ATOM   3976 N N   . ILE F  1 63 ? -41.41647 8.35979   0.10278   1.000 7.12790  ? 61  ILE A N   1 
ATOM   3977 C CA  . ILE F  1 63 ? -40.89795 7.12504   0.67970   1.000 6.67806  ? 61  ILE A CA  1 
ATOM   3978 C C   . ILE F  1 63 ? -40.81074 6.09107   -0.42505  1.000 6.69536  ? 61  ILE A C   1 
ATOM   3979 O O   . ILE F  1 63 ? -41.72591 5.98858   -1.25201  1.000 7.42031  ? 61  ILE A O   1 
ATOM   3980 C CB  . ILE F  1 63 ? -41.79457 6.58879   1.81272   1.000 7.15893  ? 61  ILE A CB  1 
ATOM   3981 C CG1 . ILE F  1 63 ? -42.15013 7.68673   2.81060   1.000 8.35397  ? 61  ILE A CG1 1 
ATOM   3982 C CG2 . ILE F  1 63 ? -41.10209 5.43420   2.52711   1.000 8.05442  ? 61  ILE A CG2 1 
ATOM   3983 C CD1 . ILE F  1 63 ? -43.22405 7.28381   3.79671   1.000 9.62168  ? 61  ILE A CD1 1 
ATOM   3984 N N   . ARG F  1 64 ? -39.72588 5.31672   -0.43013  1.000 6.73338  ? 62  ARG A N   1 
ATOM   3985 C CA  . ARG F  1 64 ? -39.60447 4.17702   -1.33139  1.000 6.33876  ? 62  ARG A CA  1 
ATOM   3986 C C   . ARG F  1 64 ? -39.29152 2.93717   -0.50890  1.000 6.63868  ? 62  ARG A C   1 
ATOM   3987 O O   . ARG F  1 64 ? -38.28447 2.90090   0.21020   1.000 7.21356  ? 62  ARG A O   1 
ATOM   3988 C CB  . ARG F  1 64 ? -38.52695 4.39666   -2.39695  1.000 6.71259  ? 62  ARG A CB  1 
ATOM   3989 C CG  . ARG F  1 64 ? -38.78859 5.57298   -3.32382  1.000 7.50368  ? 62  ARG A CG  1 
ATOM   3990 C CD  . ARG F  1 64 ? -40.02875 5.35963   -4.18472  1.000 7.60589  ? 62  ARG A CD  1 
ATOM   3991 N NE  . ARG F  1 64 ? -40.29748 6.48143   -5.08440  1.000 8.31222  ? 62  ARG A NE  1 
ATOM   3992 C CZ  . ARG F  1 64 ? -41.03405 7.54268   -4.78020  1.000 7.84940  ? 62  ARG A CZ  1 
ATOM   3993 N NH1 . ARG F  1 64 ? -41.62162 7.66261   -3.59895  1.000 8.23973  ? 62  ARG A NH1 1 
ATOM   3994 N NH2 . ARG F  1 64 ? -41.19431 8.50583   -5.68968  1.000 9.26818  ? 62  ARG A NH2 1 
ATOM   3995 N N   . VAL F  1 65 ? -40.15053 1.92968   -0.62004  1.000 7.02495  ? 63  VAL A N   1 
ATOM   3996 C CA  . VAL F  1 65 ? -40.00609 0.65550   0.07010   1.000 6.35769  ? 63  VAL A CA  1 
ATOM   3997 C C   . VAL F  1 65 ? -39.69080 -0.40102  -0.97288  1.000 7.10410  ? 63  VAL A C   1 
ATOM   3998 O O   . VAL F  1 65 ? -40.41307 -0.52434  -1.97031  1.000 8.17839  ? 63  VAL A O   1 
ATOM   3999 C CB  . VAL F  1 65 ? -41.29908 0.29646   0.82281   1.000 7.77035  ? 63  VAL A CB  1 
ATOM   4000 C CG1 . VAL F  1 65 ? -41.18811 -1.08141  1.42711   1.000 8.85332  ? 63  VAL A CG1 1 
ATOM   4001 C CG2 . VAL F  1 65 ? -41.58611 1.31714   1.91147   1.000 8.30299  ? 63  VAL A CG2 1 
ATOM   4002 N N   . TYR F  1 66 ? -38.61665 -1.15472  -0.74585  1.000 6.75433  ? 64  TYR A N   1 
ATOM   4003 C CA  . TYR F  1 66 ? -38.16832 -2.20399  -1.66001  1.000 7.51132  ? 64  TYR A CA  1 
ATOM   4004 C C   . TYR F  1 66 ? -38.52788 -3.54173  -1.02961  1.000 7.11448  ? 64  TYR A C   1 
ATOM   4005 O O   . TYR F  1 66 ? -37.93196 -3.94004  -0.02388  1.000 7.34174  ? 64  TYR A O   1 
ATOM   4006 C CB  . TYR F  1 66 ? -36.66875 -2.05311  -1.97935  1.000 7.71361  ? 64  TYR A CB  1 
ATOM   4007 C CG  . TYR F  1 66 ? -36.45134 -0.73529  -2.66257  1.000 6.97961  ? 64  TYR A CG  1 
ATOM   4008 C CD1 . TYR F  1 66 ? -36.64023 -0.59782  -4.03723  1.000 7.31720  ? 64  TYR A CD1 1 
ATOM   4009 C CD2 . TYR F  1 66 ? -36.14752 0.39668   -1.92744  1.000 6.91841  ? 64  TYR A CD2 1 
ATOM   4010 C CE1 . TYR F  1 66 ? -36.52709 0.63391   -4.64915  1.000 7.48930  ? 64  TYR A CE1 1 
ATOM   4011 C CE2 . TYR F  1 66 ? -36.03710 1.62615   -2.52971  1.000 7.42291  ? 64  TYR A CE2 1 
ATOM   4012 C CZ  . TYR F  1 66 ? -36.23112 1.74912   -3.88987  1.000 6.68828  ? 64  TYR A CZ  1 
ATOM   4013 O OH  . TYR F  1 66 ? -36.14008 2.99338   -4.46426  1.000 7.21921  ? 64  TYR A OH  1 
ATOM   4014 N N   . ALA F  1 67 ? -39.52578 -4.21031  -1.60591  1.000 7.86105  ? 65  ALA A N   1 
ATOM   4015 C CA  . ALA F  1 67 ? -40.07420 -5.45569  -1.08077  1.000 8.04697  ? 65  ALA A CA  1 
ATOM   4016 C C   . ALA F  1 67 ? -39.61657 -6.60081  -1.97040  1.000 8.28530  ? 65  ALA A C   1 
ATOM   4017 O O   . ALA F  1 67 ? -39.88720 -6.59476  -3.17641  1.000 9.97927  ? 65  ALA A O   1 
ATOM   4018 C CB  . ALA F  1 67 ? -41.59972 -5.38613  -1.08613  1.000 9.97178  ? 65  ALA A CB  1 
ATOM   4019 N N   . SER F  1 68 ? -38.95610 -7.59023  -1.38823  1.000 8.20089  ? 66  SER A N   1 
ATOM   4020 C CA  . SER F  1 68 ? -38.39539 -8.68575  -2.17058  1.000 9.44272  ? 66  SER A CA  1 
ATOM   4021 C C   . SER F  1 68 ? -39.02618 -10.01747 -1.79908  1.000 9.68677  ? 66  SER A C   1 
ATOM   4022 O O   . SER F  1 68 ? -39.12680 -10.35673 -0.61710  1.000 9.92938  ? 66  SER A O   1 
ATOM   4023 C CB  . SER F  1 68 ? -36.88117 -8.77602  -2.00565  1.000 10.08456 ? 66  SER A CB  1 
ATOM   4024 O OG  . SER F  1 68 ? -36.26504 -7.59564  -2.48546  1.000 11.36905 ? 66  SER A OG  1 
ATOM   4025 N N   . THR F  1 69 ? -39.41199 -10.77316 -2.82703  1.000 10.00460 ? 67  THR A N   1 
ATOM   4026 C CA  . THR F  1 69 ? -39.83347 -12.15981 -2.71165  1.000 11.93306 ? 67  THR A CA  1 
ATOM   4027 C C   . THR F  1 69 ? -39.11026 -12.91522 -3.81020  1.000 11.72814 ? 67  THR A C   1 
ATOM   4028 O O   . THR F  1 69 ? -39.18975 -12.52987 -4.97876  1.000 12.34948 ? 67  THR A O   1 
ATOM   4029 C CB  . THR F  1 69 ? -41.34357 -12.28898 -2.90395  1.000 11.67174 ? 67  THR A CB  1 
ATOM   4030 O OG1 . THR F  1 69 ? -42.01314 -11.51622 -1.90125  1.000 13.17515 ? 67  THR A OG1 1 
ATOM   4031 C CG2 . THR F  1 69 ? -41.77455 -13.74759 -2.78501  1.000 15.37084 ? 67  THR A CG2 1 
ATOM   4032 N N   . GLY F  1 70 ? -38.38852 -13.96372 -3.43267  1.000 13.11719 ? 68  GLY A N   1 
ATOM   4033 C CA  . GLY F  1 70 ? -37.52399 -14.61833 -4.40006  1.000 14.96498 ? 68  GLY A CA  1 
ATOM   4034 C C   . GLY F  1 70 ? -36.51542 -13.62165 -4.93373  1.000 15.41801 ? 68  GLY A C   1 
ATOM   4035 O O   . GLY F  1 70 ? -35.90886 -12.85316 -4.17854  1.000 15.72226 ? 68  GLY A O   1 
ATOM   4036 N N   . THR F  1 71 ? -36.34721 -13.60276 -6.24994  1.000 15.24167 ? 69  THR A N   1 
ATOM   4037 C CA  . THR F  1 71 ? -35.44485 -12.65510 -6.88482  1.000 15.19868 ? 69  THR A CA  1 
ATOM   4038 C C   . THR F  1 71 ? -36.14888 -11.39667 -7.37460  1.000 15.91241 ? 69  THR A C   1 
ATOM   4039 O O   . THR F  1 71 ? -35.50958 -10.55768 -8.01737  1.000 18.98908 ? 69  THR A O   1 
ATOM   4040 C CB  . THR F  1 71 ? -34.70185 -13.32438 -8.04207  1.000 23.15602 ? 69  THR A CB  1 
ATOM   4041 O OG1 . THR F  1 71 ? -35.65202 -13.83916 -8.98201  1.000 23.36580 ? 69  THR A OG1 1 
ATOM   4042 C CG2 . THR F  1 71 ? -33.83744 -14.46379 -7.52719  1.000 29.66869 ? 69  THR A CG2 1 
ATOM   4043 N N   . THR F  1 72 ? -37.43471 -11.23492 -7.07264  1.000 12.91695 ? 70  THR A N   1 
ATOM   4044 C CA  . THR F  1 72 ? -38.22221 -10.11415 -7.56748  1.000 13.21142 ? 70  THR A CA  1 
ATOM   4045 C C   . THR F  1 72 ? -38.35721 -9.06548  -6.47160  1.000 11.25362 ? 70  THR A C   1 
ATOM   4046 O O   . THR F  1 72 ? -38.96968 -9.32575  -5.42821  1.000 12.18226 ? 70  THR A O   1 
ATOM   4047 C CB  . THR F  1 72 ? -39.60382 -10.59011 -8.01318  1.000 13.96855 ? 70  THR A CB  1 
ATOM   4048 O OG1 . THR F  1 72 ? -39.45534 -11.55627 -9.06028  1.000 19.12818 ? 70  THR A OG1 1 
ATOM   4049 C CG2 . THR F  1 72 ? -40.43138 -9.42067  -8.52529  1.000 18.19987 ? 70  THR A CG2 1 
ATOM   4050 N N   . THR F  1 73 ? -37.79599 -7.88681  -6.71678  1.000 10.70769 ? 71  THR A N   1 
ATOM   4051 C CA  . THR F  1 73 ? -37.94105 -6.74595  -5.82566  1.000 9.81559  ? 71  THR A CA  1 
ATOM   4052 C C   . THR F  1 73 ? -38.93701 -5.78279  -6.44521  1.000 10.32956 ? 71  THR A C   1 
ATOM   4053 O O   . THR F  1 73 ? -38.75325 -5.34183  -7.58541  1.000 12.29802 ? 71  THR A O   1 
ATOM   4054 C CB  . THR F  1 73 ? -36.59817 -6.04527  -5.62826  1.000 12.52041 ? 71  THR A CB  1 
ATOM   4055 O OG1 . THR F  1 73 ? -35.66242 -6.96181  -5.05987  1.000 12.50151 ? 71  THR A OG1 1 
ATOM   4056 C CG2 . THR F  1 73 ? -36.74861 -4.84292  -4.70441  1.000 11.26195 ? 71  THR A CG2 1 
ATOM   4057 N N   . THR F  1 74 ? -39.98427 -5.46283  -5.69679  1.000 9.48614  ? 72  THR A N   1 
ATOM   4058 C CA  . THR F  1 74 ? -40.98499 -4.49856  -6.11430  1.000 9.55856  ? 72  THR A CA  1 
ATOM   4059 C C   . THR F  1 74 ? -40.79195 -3.23766  -5.29021  1.000 8.07671  ? 72  THR A C   1 
ATOM   4060 O O   . THR F  1 74 ? -40.73149 -3.30598  -4.05624  1.000 9.06229  ? 72  THR A O   1 
ATOM   4061 C CB  . THR F  1 74 ? -42.38675 -5.05239  -5.86328  1.000 10.15654 ? 72  THR A CB  1 
ATOM   4062 O OG1 . THR F  1 74 ? -42.55621 -6.28170  -6.57786  1.000 12.40656 ? 72  THR A OG1 1 
ATOM   4063 C CG2 . THR F  1 74 ? -43.43286 -4.06109  -6.33371  1.000 11.52649 ? 72  THR A CG2 1 
ATOM   4064 N N   . GLU F  1 75 ? -40.69792 -2.09993  -5.96578  1.000 7.78527  ? 73  GLU A N   1 
ATOM   4065 C CA  . GLU F  1 75 ? -40.60213 -0.81082  -5.30365  1.000 7.75292  ? 73  GLU A CA  1 
ATOM   4066 C C   . GLU F  1 75 ? -41.99968 -0.24579  -5.11859  1.000 7.36179  ? 73  GLU A C   1 
ATOM   4067 O O   . GLU F  1 75 ? -42.80390 -0.23198  -6.05864  1.000 9.11110  ? 73  GLU A O   1 
ATOM   4068 C CB  . GLU F  1 75 ? -39.78993 0.14746   -6.16488  1.000 7.44025  ? 73  GLU A CB  1 
ATOM   4069 C CG  . GLU F  1 75 ? -39.68560 1.56399   -5.64374  1.000 7.92412  ? 73  GLU A CG  1 
ATOM   4070 C CD  . GLU F  1 75 ? -39.06475 2.48068   -6.67563  1.000 7.95603  ? 73  GLU A CD  1 
ATOM   4071 O OE1 . GLU F  1 75 ? -39.50583 2.42581   -7.84915  1.000 8.28715  ? 73  GLU A OE1 1 
ATOM   4072 O OE2 . GLU F  1 75 ? -38.14185 3.24992   -6.33374  1.000 7.64712  ? 73  GLU A OE2 1 
ATOM   4073 N N   . TRP F  1 76 ? -42.27559 0.23051   -3.91104  1.000 7.25780  ? 74  TRP A N   1 
ATOM   4074 C CA  . TRP F  1 76 ? -43.53231 0.86865   -3.56718  1.000 7.96609  ? 74  TRP A CA  1 
ATOM   4075 C C   . TRP F  1 76 ? -43.25781 2.31645   -3.19595  1.000 7.96492  ? 74  TRP A C   1 
ATOM   4076 O O   . TRP F  1 76 ? -42.29327 2.61104   -2.47552  1.000 8.50347  ? 74  TRP A O   1 
ATOM   4077 C CB  . TRP F  1 76 ? -44.18781 0.12939   -2.40580  1.000 8.24636  ? 74  TRP A CB  1 
ATOM   4078 C CG  . TRP F  1 76 ? -44.64416 -1.22756  -2.79214  1.000 8.90548  ? 74  TRP A CG  1 
ATOM   4079 C CD1 . TRP F  1 76 ? -43.99182 -2.40210  -2.59249  1.000 8.67214  ? 74  TRP A CD1 1 
ATOM   4080 C CD2 . TRP F  1 76 ? -45.86142 -1.55201  -3.46829  1.000 11.09550 ? 74  TRP A CD2 1 
ATOM   4081 N NE1 . TRP F  1 76 ? -44.72660 -3.44770  -3.10626  1.000 10.27713 ? 74  TRP A NE1 1 
ATOM   4082 C CE2 . TRP F  1 76 ? -45.88081 -2.94878  -3.64810  1.000 12.39303 ? 74  TRP A CE2 1 
ATOM   4083 C CE3 . TRP F  1 76 ? -46.93896 -0.79590  -3.93597  1.000 13.34592 ? 74  TRP A CE3 1 
ATOM   4084 C CZ2 . TRP F  1 76 ? -46.93924 -3.60839  -4.27178  1.000 16.51652 ? 74  TRP A CZ2 1 
ATOM   4085 C CZ3 . TRP F  1 76 ? -47.99027 -1.44996  -4.55369  1.000 18.82948 ? 74  TRP A CZ3 1 
ATOM   4086 C CH2 . TRP F  1 76 ? -47.98205 -2.84455  -4.71571  1.000 19.56015 ? 74  TRP A CH2 1 
ATOM   4087 N N   . CYS F  1 77 ? -44.11161 3.21709   -3.67833  1.000 7.95573  ? 75  CYS A N   1 
ATOM   4088 C CA  . CYS F  1 77 ? -43.86194 4.64555   -3.60912  1.000 7.09584  ? 75  CYS A CA  1 
ATOM   4089 C C   . CYS F  1 77 ? -44.96748 5.34171   -2.83916  1.000 8.41932  ? 75  CYS A C   1 
ATOM   4090 O O   . CYS F  1 77 ? -46.15257 5.16997   -3.14759  1.000 8.82243  ? 75  CYS A O   1 
ATOM   4091 C CB  . CYS F  1 77 ? -43.81214 5.25362   -5.00981  1.000 9.54808  ? 75  CYS A CB  1 
ATOM   4092 S SG  . CYS F  1 77 ? -42.72699 4.42592   -6.16408  1.000 9.13201  ? 75  CYS A SG  1 
ATOM   4093 N N   . TRP F  1 78 ? -44.57587 6.14658   -1.86549  1.000 8.28474  ? 76  TRP A N   1 
ATOM   4094 C CA  . TRP F  1 78 ? -45.48120 7.05499   -1.18494  1.000 9.35119  ? 76  TRP A CA  1 
ATOM   4095 C C   . TRP F  1 78 ? -45.05365 8.46350   -1.54670  1.000 10.42233 ? 76  TRP A C   1 
ATOM   4096 O O   . TRP F  1 78 ? -43.90467 8.84107   -1.31158  1.000 10.70218 ? 76  TRP A O   1 
ATOM   4097 C CB  . TRP F  1 78 ? -45.42182 6.88381   0.33128   1.000 8.95862  ? 76  TRP A CB  1 
ATOM   4098 C CG  . TRP F  1 78 ? -46.29569 7.88359   0.99782   1.000 12.14417 ? 76  TRP A CG  1 
ATOM   4099 C CD1 . TRP F  1 78 ? -45.95388 9.13697   1.42677   1.000 15.21095 ? 76  TRP A CD1 1 
ATOM   4100 C CD2 . TRP F  1 78 ? -47.68655 7.73506   1.25542   1.000 11.66666 ? 76  TRP A CD2 1 
ATOM   4101 N NE1 . TRP F  1 78 ? -47.05464 9.76622   1.95887   1.000 14.03329 ? 76  TRP A NE1 1 
ATOM   4102 C CE2 . TRP F  1 78 ? -48.13166 8.92398   1.86859   1.000 11.80761 ? 76  TRP A CE2 1 
ATOM   4103 C CE3 . TRP F  1 78 ? -48.59695 6.69628   1.05374   1.000 10.96923 ? 76  TRP A CE3 1 
ATOM   4104 C CZ2 . TRP F  1 78 ? -49.45689 9.10804   2.27004   1.000 12.91747 ? 76  TRP A CZ2 1 
ATOM   4105 C CZ3 . TRP F  1 78 ? -49.90820 6.87964   1.45471   1.000 12.47001 ? 76  TRP A CZ3 1 
ATOM   4106 C CH2 . TRP F  1 78 ? -50.32673 8.07524   2.05287   1.000 14.79962 ? 76  TRP A CH2 1 
ATOM   4107 N N   . ASP F  1 79 ? -45.97702 9.23554   -2.11424  1.000 11.33405 ? 77  ASP A N   1 
ATOM   4108 C CA  . ASP F  1 79 ? -45.70849 10.61498  -2.49510  1.000 12.35892 ? 77  ASP A CA  1 
ATOM   4109 C C   . ASP F  1 79 ? -46.82714 11.53465  -2.02601  1.000 15.11291 ? 77  ASP A C   1 
ATOM   4110 O O   . ASP F  1 79 ? -47.09892 12.56691  -2.64842  1.000 19.19833 ? 77  ASP A O   1 
ATOM   4111 C CB  . ASP F  1 79 ? -45.47225 10.72309  -3.99894  1.000 12.59066 ? 77  ASP A CB  1 
ATOM   4112 C CG  . ASP F  1 79 ? -44.35103 9.82107   -4.46237  1.000 13.29145 ? 77  ASP A CG  1 
ATOM   4113 O OD1 . ASP F  1 79 ? -43.18309 10.14248  -4.18538  1.000 12.00864 ? 77  ASP A OD1 1 
ATOM   4114 O OD2 . ASP F  1 79 ? -44.63404 8.76016   -5.05551  1.000 16.55350 ? 77  ASP A OD2 1 
ATOM   4115 N N   . GLY F  1 80 ? -47.48633 11.16621  -0.93084  1.000 14.63439 ? 78  GLY A N   1 
ATOM   4116 C CA  . GLY F  1 80 ? -48.49565 11.99885  -0.31086  1.000 16.83432 ? 78  GLY A CA  1 
ATOM   4117 C C   . GLY F  1 80 ? -49.92245 11.55338  -0.53791  1.000 16.74017 ? 78  GLY A C   1 
ATOM   4118 O O   . GLY F  1 80 ? -50.82023 12.05345  0.15273   1.000 21.91293 ? 78  GLY A O   1 
ATOM   4119 N N   . ASN F  1 81 ? -50.17144 10.63816  -1.46966  1.000 16.26862 ? 79  ASN A N   1 
ATOM   4120 C CA  . ASN F  1 81 ? -51.53754 10.28510  -1.85234  1.000 17.05035 ? 79  ASN A CA  1 
ATOM   4121 C C   . ASN F  1 81 ? -51.62551 8.81268   -2.25634  1.000 22.03257 ? 79  ASN A C   1 
ATOM   4122 O O   . ASN F  1 81 ? -52.04376 8.46062   -3.35677  1.000 27.36336 ? 79  ASN A O   1 
ATOM   4123 C CB  . ASN F  1 81 ? -52.04104 11.20204  -2.96592  1.000 29.83610 ? 79  ASN A CB  1 
ATOM   4124 C CG  . ASN F  1 81 ? -52.06927 12.66220  -2.55800  1.000 43.41924 ? 79  ASN A CG  1 
ATOM   4125 O OD1 . ASN F  1 81 ? -51.11572 13.40277  -2.79951  1.000 40.90248 ? 79  ASN A OD1 1 
ATOM   4126 N ND2 . ASN F  1 81 ? -53.16433 13.08374  -1.93306  1.000 38.63478 ? 79  ASN A ND2 1 
ATOM   4127 N N   . GLY F  1 82 ? -51.22739 7.92022   -1.35907  1.000 16.59121 ? 80  GLY A N   1 
ATOM   4128 C CA  . GLY F  1 82 ? -51.39803 6.49741   -1.55975  1.000 14.45462 ? 80  GLY A CA  1 
ATOM   4129 C C   . GLY F  1 82 ? -50.12549 5.82300   -2.05177  1.000 11.92155 ? 80  GLY A C   1 
ATOM   4130 O O   . GLY F  1 82 ? -49.24921 6.43967   -2.66298  1.000 14.36218 ? 80  GLY A O   1 
ATOM   4131 N N   . TRP F  1 83 ? -50.03532 4.52379   -1.78959  1.000 10.71798 ? 81  TRP A N   1 
ATOM   4132 C CA  . TRP F  1 83 ? -48.89975 3.72348   -2.22816  1.000 10.60413 ? 81  TRP A CA  1 
ATOM   4133 C C   . TRP F  1 83 ? -49.12672 3.24843   -3.65650  1.000 11.43425 ? 81  TRP A C   1 
ATOM   4134 O O   . TRP F  1 83 ? -50.21300 2.76524   -3.99029  1.000 14.35283 ? 81  TRP A O   1 
ATOM   4135 C CB  . TRP F  1 83 ? -48.71612 2.52191   -1.30662  1.000 10.90933 ? 81  TRP A CB  1 
ATOM   4136 C CG  . TRP F  1 83 ? -48.21205 2.89768   0.05130   1.000 8.50146  ? 81  TRP A CG  1 
ATOM   4137 C CD1 . TRP F  1 83 ? -48.95153 3.10726   1.17716   1.000 8.72979  ? 81  TRP A CD1 1 
ATOM   4138 C CD2 . TRP F  1 83 ? -46.85117 3.12204   0.41652   1.000 8.36920  ? 81  TRP A CD2 1 
ATOM   4139 N NE1 . TRP F  1 83 ? -48.12915 3.44381   2.23052   1.000 8.12765  ? 81  TRP A NE1 1 
ATOM   4140 C CE2 . TRP F  1 83 ? -46.83321 3.46511   1.78607   1.000 8.02670  ? 81  TRP A CE2 1 
ATOM   4141 C CE3 . TRP F  1 83 ? -45.63817 3.07142   -0.28434  1.000 8.39921  ? 81  TRP A CE3 1 
ATOM   4142 C CZ2 . TRP F  1 83 ? -45.65248 3.73839   2.47174   1.000 8.56246  ? 81  TRP A CZ2 1 
ATOM   4143 C CZ3 . TRP F  1 83 ? -44.46856 3.33997   0.39611   1.000 8.98872  ? 81  TRP A CZ3 1 
ATOM   4144 C CH2 . TRP F  1 83 ? -44.48449 3.67073   1.76061   1.000 8.36246  ? 81  TRP A CH2 1 
ATOM   4145 N N   . THR F  1 84 ? -48.10101 3.38736   -4.49459  1.000 10.14471 ? 82  THR A N   1 
ATOM   4146 C CA  . THR F  1 84 ? -48.15940 2.99123   -5.89388  1.000 11.07443 ? 82  THR A CA  1 
ATOM   4147 C C   . THR F  1 84 ? -46.86628 2.27449   -6.25822  1.000 9.31291  ? 82  THR A C   1 
ATOM   4148 O O   . THR F  1 84 ? -45.79868 2.57691   -5.71505  1.000 9.97578  ? 82  THR A O   1 
ATOM   4149 C CB  . THR F  1 84 ? -48.33421 4.21748   -6.81787  1.000 14.66965 ? 82  THR A CB  1 
ATOM   4150 O OG1 . THR F  1 84 ? -47.18773 5.07681   -6.72311  1.000 16.52639 ? 82  THR A OG1 1 
ATOM   4151 C CG2 . THR F  1 84 ? -49.57033 5.01190   -6.43390  1.000 16.80312 ? 82  THR A CG2 1 
ATOM   4152 N N   . LYS F  1 85 ? -46.95553 1.33436   -7.19213  1.000 9.70327  ? 83  LYS A N   1 
ATOM   4153 C CA  . LYS F  1 85 ? -45.75662 0.62775   -7.62239  1.000 11.22251 ? 83  LYS A CA  1 
ATOM   4154 C C   . LYS F  1 85 ? -44.86262 1.54305   -8.44598  1.000 8.81525  ? 83  LYS A C   1 
ATOM   4155 O O   . LYS F  1 85 ? -45.33640 2.29198   -9.30621  1.000 9.98263  ? 83  LYS A O   1 
ATOM   4156 C CB  . LYS F  1 85 ? -46.11565 -0.60793  -8.44858  1.000 13.27761 ? 83  LYS A CB  1 
ATOM   4157 C CG  . LYS F  1 85 ? -46.65441 -1.76139  -7.63887  1.000 21.79840 ? 83  LYS A CG  1 
ATOM   4158 C CD  . LYS F  1 85 ? -46.43318 -3.09672  -8.33260  1.000 24.19529 ? 83  LYS A CD  1 
ATOM   4159 C CE  . LYS F  1 85 ? -46.98843 -3.08530  -9.74476  1.000 30.36139 ? 83  LYS A CE  1 
ATOM   4160 N NZ  . LYS F  1 85 ? -47.59465 -4.39607  -10.10276 1.000 26.31228 ? 83  LYS A NZ  1 
ATOM   4161 N N   . GLY F  1 86 ? -43.55653 1.46822   -8.18040  1.000 8.84318  ? 84  GLY A N   1 
ATOM   4162 C CA  . GLY F  1 86 ? -42.56861 2.23142   -8.90361  1.000 9.49483  ? 84  GLY A CA  1 
ATOM   4163 C C   . GLY F  1 86 ? -41.90476 1.43342   -10.01560 1.000 8.09073  ? 84  GLY A C   1 
ATOM   4164 O O   . GLY F  1 86 ? -42.14084 0.24423   -10.21390 1.000 8.51378  ? 84  GLY A O   1 
ATOM   4165 N N   . ALA F  1 87 ? -41.03676 2.12818   -10.74558 1.000 7.88416  ? 85  ALA A N   1 
ATOM   4166 C CA  . ALA F  1 87 ? -40.42494 1.55785   -11.93867 1.000 8.37865  ? 85  ALA A CA  1 
ATOM   4167 C C   . ALA F  1 87 ? -39.22350 0.65350   -11.66093 1.000 8.11904  ? 85  ALA A C   1 
ATOM   4168 O O   . ALA F  1 87 ? -38.72346 0.04062   -12.61141 1.000 9.51157  ? 85  ALA A O   1 
ATOM   4169 C CB  . ALA F  1 87 ? -40.00760 2.66799   -12.90470 1.000 9.63478  ? 85  ALA A CB  1 
ATOM   4170 N N   . TYR F  1 88 ? -38.74899 0.54855   -10.41415 1.000 8.33600  ? 86  TYR A N   1 
ATOM   4171 C CA  . TYR F  1 88 ? -37.54683 -0.22875  -10.12258 1.000 7.93026  ? 86  TYR A CA  1 
ATOM   4172 C C   . TYR F  1 88 ? -37.63208 -1.63422  -10.69858 1.000 7.91499  ? 86  TYR A C   1 
ATOM   4173 O O   . TYR F  1 88 ? -38.63871 -2.32815  -10.53880 1.000 9.22441  ? 86  TYR A O   1 
ATOM   4174 C CB  . TYR F  1 88 ? -37.35244 -0.34437  -8.60740  1.000 7.35104  ? 86  TYR A CB  1 
ATOM   4175 C CG  . TYR F  1 88 ? -36.16967 -1.21969  -8.25459  1.000 7.47294  ? 86  TYR A CG  1 
ATOM   4176 C CD1 . TYR F  1 88 ? -36.30880 -2.59422  -8.08847  1.000 7.99722  ? 86  TYR A CD1 1 
ATOM   4177 C CD2 . TYR F  1 88 ? -34.90660 -0.67310  -8.10887  1.000 7.88491  ? 86  TYR A CD2 1 
ATOM   4178 C CE1 . TYR F  1 88 ? -35.21978 -3.39353  -7.79434  1.000 9.80240  ? 86  TYR A CE1 1 
ATOM   4179 C CE2 . TYR F  1 88 ? -33.81361 -1.46849  -7.80952  1.000 8.62115  ? 86  TYR A CE2 1 
ATOM   4180 C CZ  . TYR F  1 88 ? -33.97293 -2.82556  -7.65364  1.000 8.18542  ? 86  TYR A CZ  1 
ATOM   4181 O OH  . TYR F  1 88 ? -32.87250 -3.60712  -7.36004  1.000 9.37683  ? 86  TYR A OH  1 
ATOM   4182 N N   . THR F  1 89 ? -36.54244 -2.06172  -11.33447 1.000 7.75532  ? 87  THR A N   1 
ATOM   4183 C CA  . THR F  1 89 ? -36.29038 -3.45755  -11.65473 1.000 9.78195  ? 87  THR A CA  1 
ATOM   4184 C C   . THR F  1 89 ? -34.83334 -3.74890  -11.33219 1.000 10.02846 ? 87  THR A C   1 
ATOM   4185 O O   . THR F  1 89 ? -33.99013 -2.84735  -11.30720 1.000 9.84153  ? 87  THR A O   1 
ATOM   4186 C CB  . THR F  1 89 ? -36.51676 -3.77965  -13.13878 1.000 11.12237 ? 87  THR A CB  1 
ATOM   4187 O OG1 . THR F  1 89 ? -35.67009 -2.94346  -13.93575 1.000 11.16937 ? 87  THR A OG1 1 
ATOM   4188 C CG2 . THR F  1 89 ? -37.96991 -3.56445  -13.53278 1.000 13.06224 ? 87  THR A CG2 1 
ATOM   4189 N N   . ALA F  1 90 ? -34.54320 -5.02576  -11.09564 1.000 13.58802 ? 88  ALA A N   1 
ATOM   4190 C CA  . ALA F  1 90 ? -33.19416 -5.42311  -10.72621 1.000 16.21481 ? 88  ALA A CA  1 
ATOM   4191 C C   . ALA F  1 90 ? -32.32967 -5.59475  -11.97253 1.000 22.92513 ? 88  ALA A C   1 
ATOM   4192 O O   . ALA F  1 90 ? -32.82620 -5.68145  -13.09858 1.000 26.97559 ? 88  ALA A O   1 
ATOM   4193 C CB  . ALA F  1 90 ? -33.21464 -6.71164  -9.90412  1.000 20.90662 ? 88  ALA A CB  1 
ATOM   4194 N N   . THR F  1 91 ? -31.01209 -5.64296  -11.75658 1.000 24.03140 ? 89  THR A N   1 
ATOM   4195 C CA  . THR F  1 91 ? -30.07963 -5.72942  -12.87725 0.000 18.33293 ? 89  THR A CA  1 
ATOM   4196 C C   . THR F  1 91 ? -30.25470 -7.00428  -13.69472 0.000 20.00692 ? 89  THR A C   1 
ATOM   4197 O O   . THR F  1 91 ? -29.81646 -7.05033  -14.84956 0.000 19.97011 ? 89  THR A O   1 
ATOM   4198 C CB  . THR F  1 91 ? -28.63630 -5.61502  -12.38132 0.000 17.19521 ? 89  THR A CB  1 
ATOM   4199 O OG1 . THR F  1 91 ? -27.74261 -5.62671  -13.50174 0.000 17.69682 ? 89  THR A OG1 1 
ATOM   4200 C CG2 . THR F  1 91 ? -28.29582 -6.77434  -11.45675 0.000 17.84827 ? 89  THR A CG2 1 
ATOM   4201 N N   . ASN F  1 92 ? -30.88222 -8.03140  -13.13172 0.000 19.96314 ? 90  ASN A N   1 
ATOM   4202 C CA  . ASN F  1 92 ? -31.08492 -9.28839  -13.84252 0.000 19.93830 ? 90  ASN A CA  1 
ATOM   4203 C C   . ASN F  1 92 ? -32.51855 -9.42134  -14.34853 0.000 20.51016 ? 90  ASN A C   1 
ATOM   4204 O O   . ASN F  1 92 ? -33.03901 -8.52413  -15.01162 0.000 20.76717 ? 90  ASN A O   1 
ATOM   4205 C CB  . ASN F  1 92 ? -30.72642 -10.47244 -12.94198 0.000 19.66469 ? 90  ASN A CB  1 
ATOM   4206 C CG  . ASN F  1 92 ? -31.31155 -10.34348 -11.54836 0.000 19.84699 ? 90  ASN A CG  1 
ATOM   4207 O OD1 . ASN F  1 92 ? -32.28028 -9.61508  -11.33249 0.000 20.29595 ? 90  ASN A OD1 1 
ATOM   4208 N ND2 . ASN F  1 92 ? -30.72030 -11.04975 -10.59197 0.000 19.42118 ? 90  ASN A ND2 1 
HETATM 4209 C C1  . BDF G  2 .  ? -20.44379 5.97949   -46.51510 1.000 12.07586 ? 101 BDF B C1  1 
HETATM 4210 C C2  . BDF G  2 .  ? -18.98723 5.80837   -46.91921 1.000 9.20302  ? 101 BDF B C2  1 
HETATM 4211 C C3  . BDF G  2 .  ? -18.57989 4.33450   -47.04800 1.000 8.31867  ? 101 BDF B C3  1 
HETATM 4212 C C4  . BDF G  2 .  ? -17.07838 4.23166   -47.30427 1.000 8.56159  ? 101 BDF B C4  1 
HETATM 4213 C C5  . BDF G  2 .  ? -16.31785 4.95191   -46.20080 1.000 8.98070  ? 101 BDF B C5  1 
HETATM 4214 C C6  . BDF G  2 .  ? -16.80311 6.38396   -46.12214 1.000 9.82006  ? 101 BDF B C6  1 
HETATM 4215 O O1  . BDF G  2 .  ? -20.80558 5.09527   -45.46601 1.000 29.35295 ? 101 BDF B O1  1 
HETATM 4216 O O2  . BDF G  2 .  ? -18.73572 6.42891   -48.15076 1.000 11.13542 ? 101 BDF B O2  1 
HETATM 4217 O O3  . BDF G  2 .  ? -19.31073 3.69892   -48.09180 1.000 8.88589  ? 101 BDF B O3  1 
HETATM 4218 O O4  . BDF G  2 .  ? -16.68760 2.86829   -47.39223 1.000 8.63754  ? 101 BDF B O4  1 
HETATM 4219 O O5  . BDF G  2 .  ? -16.57279 4.35137   -44.92813 1.000 8.43677  ? 101 BDF B O5  1 
HETATM 4220 O O6  . BDF G  2 .  ? -18.21733 6.42107   -45.88854 1.000 9.27039  ? 101 BDF B O6  1 
HETATM 4221 C C1  . BDF H  2 .  ? -27.76524 4.91946   -29.30144 1.000 14.62266 ? 102 BDF B C1  1 
HETATM 4222 C C2  . BDF H  2 .  ? -27.37184 4.78594   -30.76393 1.000 13.25252 ? 102 BDF B C2  1 
HETATM 4223 C C3  . BDF H  2 .  ? -27.18352 3.31109   -31.14665 1.000 12.58508 ? 102 BDF B C3  1 
HETATM 4224 C C4  . BDF H  2 .  ? -26.56981 3.19210   -32.53758 1.000 11.08161 ? 102 BDF B C4  1 
HETATM 4225 C C5  . BDF H  2 .  ? -25.27895 3.99510   -32.60178 1.000 12.36436 ? 102 BDF B C5  1 
HETATM 4226 C C6  . BDF H  2 .  ? -25.56965 5.43098   -32.21397 1.000 11.80803 ? 102 BDF B C6  1 
HETATM 4227 O O1  . BDF H  2 .  ? -28.03714 6.26877   -28.95434 1.000 26.71089 ? 102 BDF B O1  1 
HETATM 4228 O O2  . BDF H  2 .  ? -28.34541 5.33999   -31.60864 1.000 13.21984 ? 102 BDF B O2  1 
HETATM 4229 O O3  . BDF H  2 .  ? -28.43007 2.62511   -31.09377 1.000 12.50530 ? 102 BDF B O3  1 
HETATM 4230 O O4  . BDF H  2 .  ? -26.34920 1.81996   -32.84249 1.000 11.70197 ? 102 BDF B O4  1 
HETATM 4231 O O5  . BDF H  2 .  ? -24.31319 3.48311   -31.68296 1.000 11.79738 ? 102 BDF B O5  1 
HETATM 4232 O O6  . BDF H  2 .  ? -26.13784 5.48610   -30.89795 1.000 12.07652 ? 102 BDF B O6  1 
HETATM 4233 O O3  . T3Y I  3 .  ? -3.64925  -22.83170 -23.37204 1.000 11.00965 ? 101 T3Y C O3  1 
HETATM 4234 S S1  . T3Y I  3 .  ? -3.32388  -24.02061 -22.56932 1.000 9.24908  ? 101 T3Y C S1  1 
HETATM 4235 O O1  . T3Y I  3 .  ? -2.81541  -23.65290 -21.27480 1.000 11.67129 ? 101 T3Y C O1  1 
HETATM 4236 O O2  . T3Y I  3 .  ? -4.43556  -24.93628 -22.51073 1.000 11.85298 ? 101 T3Y C O2  1 
HETATM 4237 C C1  . T3Y I  3 .  ? -2.02405  -24.88090 -23.41084 1.000 9.13158  ? 101 T3Y C C1  1 
HETATM 4238 C C24 . T3Y I  3 .  ? -2.28115  -25.45310 -24.64377 1.000 10.75052 ? 101 T3Y C C24 1 
HETATM 4239 C C23 . T3Y I  3 .  ? -1.29773  -26.16485 -25.31486 1.000 8.75054  ? 101 T3Y C C23 1 
HETATM 4240 C C22 . T3Y I  3 .  ? -1.58586  -26.78551 -26.67390 1.000 10.05403 ? 101 T3Y C C22 1 
HETATM 4241 C C2  . T3Y I  3 .  ? -0.78078  -25.01315 -22.81662 1.000 8.25688  ? 101 T3Y C C2  1 
HETATM 4242 C C3  . T3Y I  3 .  ? 0.23093   -25.72245 -23.45056 1.000 8.30261  ? 101 T3Y C C3  1 
HETATM 4243 C C25 . T3Y I  3 .  ? -0.04487  -26.29150 -24.70074 1.000 8.06181  ? 101 T3Y C C25 1 
HETATM 4244 O O13 . T3Y I  3 .  ? 0.93000   -27.00414 -25.32536 1.000 10.02856 ? 101 T3Y C O13 1 
HETATM 4245 C C4  . T3Y I  3 .  ? 1.59622   -25.87411 -22.80356 1.000 8.66650  ? 101 T3Y C C4  1 
HETATM 4246 C C5  . T3Y I  3 .  ? 2.71042   -25.07514 -23.45760 1.000 8.73692  ? 101 T3Y C C5  1 
HETATM 4247 C C6  . T3Y I  3 .  ? 2.93353   -23.75840 -23.08737 1.000 8.91107  ? 101 T3Y C C6  1 
HETATM 4248 C C7  . T3Y I  3 .  ? 3.94872   -23.02323 -23.67603 1.000 9.80455  ? 101 T3Y C C7  1 
HETATM 4249 S S2  . T3Y I  3 .  ? 4.21775   -21.33973 -23.18333 1.000 11.70089 ? 101 T3Y C S2  1 
HETATM 4250 O O4  . T3Y I  3 .  ? 5.27020   -21.36348 -22.20411 1.000 14.86695 ? 101 T3Y C O4  1 
HETATM 4251 O O5  . T3Y I  3 .  ? 2.94377   -20.82799 -22.61761 1.000 11.35735 ? 101 T3Y C O5  1 
HETATM 4252 O O6  . T3Y I  3 .  ? 4.60953   -20.61338 -24.36175 1.000 13.56641 ? 101 T3Y C O6  1 
HETATM 4253 C C8  . T3Y I  3 .  ? 4.77871   -23.60285 -24.62480 1.000 9.25560  ? 101 T3Y C C8  1 
HETATM 4254 C C28 . T3Y I  3 .  ? 3.55204   -25.64174 -24.42691 1.000 8.89320  ? 101 T3Y C C28 1 
HETATM 4255 O O16 . T3Y I  3 .  ? 3.35069   -26.92873 -24.81019 1.000 10.57173 ? 101 T3Y C O16 1 
HETATM 4256 C C9  . T3Y I  3 .  ? 4.60076   -24.92370 -25.01686 1.000 8.82885  ? 101 T3Y C C9  1 
HETATM 4257 C C10 . T3Y I  3 .  ? 5.49424   -25.55795 -26.07484 1.000 9.64980  ? 101 T3Y C C10 1 
HETATM 4258 C C11 . T3Y I  3 .  ? 4.95704   -25.27906 -27.46502 1.000 9.95918  ? 101 T3Y C C11 1 
HETATM 4259 C C12 . T3Y I  3 .  ? 5.41689   -24.18135 -28.17469 1.000 9.33712  ? 101 T3Y C C12 1 
HETATM 4260 C C13 . T3Y I  3 .  ? 4.92102   -23.90137 -29.43235 1.000 10.38629 ? 101 T3Y C C13 1 
HETATM 4261 S S3  . T3Y I  3 .  ? 5.51327   -22.47628 -30.28916 1.000 11.57834 ? 101 T3Y C S3  1 
HETATM 4262 O O7  . T3Y I  3 .  ? 5.53674   -22.80887 -31.68983 1.000 11.82824 ? 101 T3Y C O7  1 
HETATM 4263 O O8  . T3Y I  3 .  ? 6.85935   -22.20182 -29.77504 1.000 13.79182 ? 101 T3Y C O8  1 
HETATM 4264 O O9  . T3Y I  3 .  ? 4.61998   -21.40816 -29.92359 1.000 12.31513 ? 101 T3Y C O9  1 
HETATM 4265 C C14 . T3Y I  3 .  ? 3.94533   -24.69933 -30.00164 1.000 10.35869 ? 101 T3Y C C14 1 
HETATM 4266 C C27 . T3Y I  3 .  ? 3.97231   -26.08710 -28.04986 1.000 9.58706  ? 101 T3Y C C27 1 
HETATM 4267 O O15 . T3Y I  3 .  ? 3.50107   -27.18233 -27.38916 1.000 9.59322  ? 101 T3Y C O15 1 
HETATM 4268 C C15 . T3Y I  3 .  ? 3.45985   -25.81062 -29.32389 1.000 9.67715  ? 101 T3Y C C15 1 
HETATM 4269 C C16 . T3Y I  3 .  ? 2.35472   -26.65878 -29.92842 1.000 10.31919 ? 101 T3Y C C16 1 
HETATM 4270 C C17 . T3Y I  3 .  ? 1.04886   -26.08431 -29.39461 1.000 9.52376  ? 101 T3Y C C17 1 
HETATM 4271 C C18 . T3Y I  3 .  ? 0.53826   -24.90733 -29.92726 1.000 11.45730 ? 101 T3Y C C18 1 
HETATM 4272 C C26 . T3Y I  3 .  ? 0.35432   -26.67984 -28.32918 1.000 9.98411  ? 101 T3Y C C26 1 
HETATM 4273 O O14 . T3Y I  3 .  ? 0.83150   -27.83038 -27.77307 1.000 10.34678 ? 101 T3Y C O14 1 
HETATM 4274 C C21 . T3Y I  3 .  ? -0.83726  -26.13398 -27.82621 1.000 9.87060  ? 101 T3Y C C21 1 
HETATM 4275 C C20 . T3Y I  3 .  ? -1.31340  -24.95925 -28.39489 1.000 10.66803 ? 101 T3Y C C20 1 
HETATM 4276 C C19 . T3Y I  3 .  ? -0.63691  -24.35751 -29.44293 1.000 11.69864 ? 101 T3Y C C19 1 
HETATM 4277 S S4  . T3Y I  3 .  ? -1.25637  -22.85266 -30.14675 1.000 13.26586 ? 101 T3Y C S4  1 
HETATM 4278 O O11 . T3Y I  3 .  ? -1.78222  -23.18324 -31.44638 1.000 17.15960 ? 101 T3Y C O11 1 
HETATM 4279 O O10 . T3Y I  3 .  ? -0.09563  -21.94914 -30.26062 1.000 16.54873 ? 101 T3Y C O10 1 
HETATM 4280 O O12 . T3Y I  3 .  ? -2.21179  -22.32108 -29.20808 1.000 15.60982 ? 101 T3Y C O12 1 
HETATM 4281 C C1  . BDF J  2 .  ? 1.85204   7.08597   -16.67176 1.000 10.79692 ? 102 BDF C C1  1 
HETATM 4282 C C2  . BDF J  2 .  ? 0.39105   6.86526   -16.31461 1.000 9.47153  ? 102 BDF C C2  1 
HETATM 4283 C C3  . BDF J  2 .  ? 0.05684   5.36896   -16.23782 1.000 8.81519  ? 102 BDF C C3  1 
HETATM 4284 C C4  . BDF J  2 .  ? -1.44776  5.17509   -16.07203 1.000 9.56653  ? 102 BDF C C4  1 
HETATM 4285 C C5  . BDF J  2 .  ? -2.18824  5.88372   -17.19699 1.000 8.12823  ? 102 BDF C C5  1 
HETATM 4286 C C6  . BDF J  2 .  ? -1.78372  7.34346   -17.21138 1.000 9.49742  ? 102 BDF C C6  1 
HETATM 4287 O O1  . BDF J  2 .  ? 2.24463   8.43725   -16.47652 1.000 15.10654 ? 102 BDF C O1  1 
HETATM 4288 O O2  . BDF J  2 .  ? 0.06209   7.45576   -15.08597 1.000 10.73202 ? 102 BDF C O2  1 
HETATM 4289 O O3  . BDF J  2 .  ? 0.76471   4.75102   -15.16546 1.000 10.15894 ? 102 BDF C O3  1 
HETATM 4290 O O4  . BDF J  2 .  ? -1.76288  3.78981   -16.03284 1.000 9.61976  ? 102 BDF C O4  1 
HETATM 4291 O O5  . BDF J  2 .  ? -1.84172  5.32328   -18.46468 1.000 9.18320  ? 102 BDF C O5  1 
HETATM 4292 O O6  . BDF J  2 .  ? -0.36266  7.47074   -17.36163 1.000 9.85626  ? 102 BDF C O6  1 
HETATM 4293 C C1  . BDF K  2 .  ? -16.39290 6.07963   -14.36330 1.000 16.06805 ? 103 BDF C C1  1 
HETATM 4294 C C2  . BDF K  2 .  ? -17.53828 5.91464   -15.34914 1.000 11.35960 ? 103 BDF C C2  1 
HETATM 4295 C C3  . BDF K  2 .  ? -17.80167 4.43433   -15.65668 1.000 10.99177 ? 103 BDF C C3  1 
HETATM 4296 C C4  . BDF K  2 .  ? -18.81510 4.30297   -16.78667 1.000 11.89406 ? 103 BDF C C4  1 
HETATM 4297 C C5  . BDF K  2 .  ? -18.32289 5.07284   -18.00264 1.000 9.49061  ? 103 BDF C C5  1 
HETATM 4298 C C6  . BDF K  2 .  ? -18.08749 6.51580   -17.60635 1.000 11.29387 ? 103 BDF C C6  1 
HETATM 4299 O O1  . BDF K  2 .  ? -16.22922 7.43836   -13.98762 1.000 23.37280 ? 103 BDF C O1  1 
HETATM 4300 O O2  . BDF K  2 .  ? -18.72676 6.47352   -14.85560 1.000 14.09686 ? 103 BDF C O2  1 
HETATM 4301 O O3  . BDF K  2 .  ? -18.26697 3.76795   -14.48874 1.000 12.54420 ? 103 BDF C O3  1 
HETATM 4302 O O4  . BDF K  2 .  ? -19.03133 2.93007   -17.09254 1.000 10.17809 ? 103 BDF C O4  1 
HETATM 4303 O O5  . BDF K  2 .  ? -17.07508 4.54675   -18.45931 1.000 9.99228  ? 103 BDF C O5  1 
HETATM 4304 O O6  . BDF K  2 .  ? -17.13512 6.59097   -16.53650 1.000 10.84402 ? 103 BDF C O6  1 
HETATM 4305 O O3  . T3Y L  3 .  ? -20.14034 -22.74411 -47.71447 1.000 22.38894 ? 101 T3Y E O3  1 
HETATM 4306 S S1  . T3Y L  3 .  ? -19.61281 -23.13119 -46.38966 1.000 21.70748 ? 101 T3Y E S1  1 
HETATM 4307 O O1  . T3Y L  3 .  ? -20.69368 -23.40883 -45.47935 1.000 27.19164 ? 101 T3Y E O1  1 
HETATM 4308 O O2  . T3Y L  3 .  ? -18.66157 -22.15341 -45.92835 1.000 31.09254 ? 101 T3Y E O2  1 
HETATM 4309 C C1  . T3Y L  3 .  ? -18.71852 -24.64477 -46.60241 1.000 18.88023 ? 101 T3Y E C1  1 
HETATM 4310 C C24 . T3Y L  3 .  ? -18.64869 -25.56212 -45.56626 1.000 18.28286 ? 101 T3Y E C24 1 
HETATM 4311 C C23 . T3Y L  3 .  ? -17.94841 -26.75240 -45.71724 1.000 16.20781 ? 101 T3Y E C23 1 
HETATM 4312 C C22 . T3Y L  3 .  ? -17.86601 -27.75444 -44.57605 1.000 16.89148 ? 101 T3Y E C22 1 
HETATM 4313 C C2  . T3Y L  3 .  ? -18.07865 -24.88880 -47.80294 1.000 15.70978 ? 101 T3Y E C2  1 
HETATM 4314 C C3  . T3Y L  3 .  ? -17.37544 -26.06610 -47.99800 1.000 12.80104 ? 101 T3Y E C3  1 
HETATM 4315 C C25 . T3Y L  3 .  ? -17.30884 -26.98890 -46.94301 1.000 15.63017 ? 101 T3Y E C25 1 
HETATM 4316 O O13 . T3Y L  3 .  ? -16.62306 -28.15416 -47.10539 1.000 16.28521 ? 101 T3Y E O13 1 
HETATM 4317 C C4  . T3Y L  3 .  ? -16.66527 -26.30608 -49.31747 1.000 13.23817 ? 101 T3Y E C4  1 
HETATM 4318 C C5  . T3Y L  3 .  ? -15.28801 -25.66774 -49.25193 1.000 11.55282 ? 101 T3Y E C5  1 
HETATM 4319 C C6  . T3Y L  3 .  ? -15.08960 -24.36319 -49.68168 1.000 12.63552 ? 101 T3Y E C6  1 
HETATM 4320 C C7  . T3Y L  3 .  ? -13.83576 -23.77815 -49.60931 1.000 11.80561 ? 101 T3Y E C7  1 
HETATM 4321 S S2  . T3Y L  3 .  ? -13.61063 -22.11786 -50.18208 1.000 16.27258 ? 101 T3Y E S2  1 
HETATM 4322 O O4  . T3Y L  3 .  ? -13.89473 -22.12811 -51.59352 1.000 21.56015 ? 101 T3Y E O4  1 
HETATM 4323 O O5  . T3Y L  3 .  ? -14.58229 -21.27513 -49.45010 1.000 23.64040 ? 101 T3Y E O5  1 
HETATM 4324 O O6  . T3Y L  3 .  ? -12.25943 -21.73599 -49.86378 1.000 19.77779 ? 101 T3Y E O6  1 
HETATM 4325 C C8  . T3Y L  3 .  ? -12.75654 -24.48036 -49.10212 1.000 11.84862 ? 101 T3Y E C8  1 
HETATM 4326 C C28 . T3Y L  3 .  ? -14.18958 -26.36358 -48.73406 1.000 11.73909 ? 101 T3Y E C28 1 
HETATM 4327 O O16 . T3Y L  3 .  ? -14.35531 -27.64270 -48.29632 1.000 14.95990 ? 101 T3Y E O16 1 
HETATM 4328 C C9  . T3Y L  3 .  ? -12.91910 -25.78188 -48.65092 1.000 11.64121 ? 101 T3Y E C9  1 
HETATM 4329 C C10 . T3Y L  3 .  ? -11.74136 -26.56235 -48.10175 1.000 12.45977 ? 101 T3Y E C10 1 
HETATM 4330 C C11 . T3Y L  3 .  ? -11.55883 -26.45653 -46.59912 1.000 12.51806 ? 101 T3Y E C11 1 
HETATM 4331 C C12 . T3Y L  3 .  ? -10.62526 -25.57923 -46.07157 1.000 13.20082 ? 101 T3Y E C12 1 
HETATM 4332 C C13 . T3Y L  3 .  ? -10.43823 -25.48630 -44.70499 1.000 15.10007 ? 101 T3Y E C13 1 
HETATM 4333 S S3  . T3Y L  3 .  ? -9.22660  -24.36173 -44.06699 1.000 22.11382 ? 101 T3Y E S3  1 
HETATM 4334 O O7  . T3Y L  3 .  ? -8.81584  -24.87388 -42.78553 1.000 40.70434 ? 101 T3Y E O7  1 
HETATM 4335 O O8  . T3Y L  3 .  ? -9.90090  -23.05296 -43.90442 1.000 32.73057 ? 101 T3Y E O8  1 
HETATM 4336 O O9  . T3Y L  3 .  ? -8.18068  -24.26572 -45.05287 1.000 24.58988 ? 101 T3Y E O9  1 
HETATM 4337 C C14 . T3Y L  3 .  ? -11.17866 -26.27314 -43.83752 1.000 13.63418 ? 101 T3Y E C14 1 
HETATM 4338 C C27 . T3Y L  3 .  ? -12.29458 -27.25660 -45.71371 1.000 13.87028 ? 101 T3Y E C27 1 
HETATM 4339 O O15 . T3Y L  3 .  ? -13.21487 -28.13104 -46.20767 1.000 16.68835 ? 101 T3Y E O15 1 
HETATM 4340 C C15 . T3Y L  3 .  ? -12.11906 -27.17007 -44.32581 1.000 14.24233 ? 101 T3Y E C15 1 
HETATM 4341 C C16 . T3Y L  3 .  ? -12.91827 -28.04673 -43.37641 1.000 17.45441 ? 101 T3Y E C16 1 
HETATM 4342 C C17 . T3Y L  3 .  ? -14.32207 -27.55471 -43.08216 1.000 16.11065 ? 101 T3Y E C17 1 
HETATM 4343 C C18 . T3Y L  3 .  ? -14.56438 -26.78109 -41.95831 1.000 19.01898 ? 101 T3Y E C18 1 
HETATM 4344 C C26 . T3Y L  3 .  ? -15.40271 -27.87565 -43.91654 1.000 17.65570 ? 101 T3Y E C26 1 
HETATM 4345 O O14 . T3Y L  3 .  ? -15.17958 -28.64177 -45.01851 1.000 17.48609 ? 101 T3Y E O14 1 
HETATM 4346 C C21 . T3Y L  3 .  ? -16.70310 -27.42473 -43.65278 1.000 20.11974 ? 101 T3Y E C21 1 
HETATM 4347 C C20 . T3Y L  3 .  ? -16.90186 -26.65020 -42.51919 1.000 21.20497 ? 101 T3Y E C20 1 
HETATM 4348 C C19 . T3Y L  3 .  ? -15.84634 -26.34596 -41.67606 1.000 17.01626 ? 101 T3Y E C19 1 
HETATM 4349 S S4  . T3Y L  3 .  ? -16.13640 -25.35379 -40.24209 1.000 21.54915 ? 101 T3Y E S4  1 
HETATM 4350 O O11 . T3Y L  3 .  ? -17.27748 -25.92107 -39.56882 1.000 28.98027 ? 101 T3Y E O11 1 
HETATM 4351 O O10 . T3Y L  3 .  ? -14.91690 -25.44065 -39.40030 1.000 29.51762 ? 101 T3Y E O10 1 
HETATM 4352 O O12 . T3Y L  3 .  ? -16.33668 -24.01532 -40.73446 1.000 20.04413 ? 101 T3Y E O12 1 
HETATM 4353 C C1  . BDF M  2 .  ? -1.87445  5.78959   -48.90417 1.000 10.21042 ? 102 BDF E C1  1 
HETATM 4354 C C2  . BDF M  2 .  ? -0.83076  5.72220   -47.80299 1.000 9.27802  ? 102 BDF E C2  1 
HETATM 4355 C C3  . BDF M  2 .  ? -0.52929  4.25866   -47.45573 1.000 10.32548 ? 102 BDF E C3  1 
HETATM 4356 C C4  . BDF M  2 .  ? 0.34071   4.18135   -46.20686 1.000 10.01342 ? 102 BDF E C4  1 
HETATM 4357 C C5  . BDF M  2 .  ? -0.31201  4.95379   -45.06738 1.000 9.08213  ? 102 BDF E C5  1 
HETATM 4358 C C6  . BDF M  2 .  ? -0.55954  6.37897   -45.51701 1.000 9.69562  ? 102 BDF E C6  1 
HETATM 4359 O O1  . BDF M  2 .  ? -2.05291  7.11281   -49.37574 1.000 15.84207 ? 102 BDF E O1  1 
HETATM 4360 O O2  . BDF M  2 .  ? 0.37458   6.33559   -48.18016 1.000 10.14456 ? 102 BDF E O2  1 
HETATM 4361 O O3  . BDF M  2 .  ? 0.08816   3.60492   -48.56510 1.000 10.67078 ? 102 BDF E O3  1 
HETATM 4362 O O4  . BDF M  2 .  ? 0.56992   2.81703   -45.87220 1.000 9.52355  ? 102 BDF E O4  1 
HETATM 4363 O O5  . BDF M  2 .  ? -1.58073  4.39678   -44.71206 1.000 9.60602  ? 102 BDF E O5  1 
HETATM 4364 O O6  . BDF M  2 .  ? -1.40303  6.38261   -46.67595 1.000 9.76645  ? 102 BDF E O6  1 
HETATM 4365 C C1  . BDF N  2 .  ? 8.99996   7.29336   -34.17523 1.000 15.55456 ? 103 BDF E C1  1 
HETATM 4366 C C2  . BDF N  2 .  ? 8.66158   7.18341   -32.69706 1.000 13.39981 ? 103 BDF E C2  1 
HETATM 4367 C C3  . BDF N  2 .  ? 8.64735   5.72394   -32.22117 1.000 14.69984 ? 103 BDF E C3  1 
HETATM 4368 C C4  . BDF N  2 .  ? 8.13457   5.64125   -30.78844 1.000 11.96933 ? 103 BDF E C4  1 
HETATM 4369 C C5  . BDF N  2 .  ? 6.76490   6.29593   -30.69925 1.000 11.45329 ? 103 BDF E C5  1 
HETATM 4370 C C6  . BDF N  2 .  ? 6.85914   7.71994   -31.21047 1.000 11.36760 ? 103 BDF E C6  1 
HETATM 4371 O O1  . BDF N  2 .  ? 9.17680   8.64936   -34.55942 1.000 23.57902 ? 103 BDF E O1  1 
HETATM 4372 O O2  . BDF N  2 .  ? 9.58718   7.88170   -31.90769 1.000 14.97411 ? 103 BDF E O2  1 
HETATM 4373 O O3  . BDF N  2 .  ? 9.94961   5.16166   -32.28744 1.000 17.44418 ? 103 BDF E O3  1 
HETATM 4374 O O4  . BDF N  2 .  ? 8.10784   4.28241   -30.35511 1.000 11.83325 ? 103 BDF E O4  1 
HETATM 4375 O O5  . BDF N  2 .  ? 5.82853   5.59301   -31.51791 1.000 10.92350 ? 103 BDF E O5  1 
HETATM 4376 O O6  . BDF N  2 .  ? 7.36181   7.74853   -32.55428 1.000 14.15954 ? 103 BDF E O6  1 
HETATM 4377 C C1  . BDF O  2 .  ? -23.56016 5.99631   -11.24377 1.000 12.17679 ? 101 BDF F C1  1 
HETATM 4378 C C2  . BDF O  2 .  ? -22.54237 5.82841   -10.12939 1.000 10.08343 ? 101 BDF F C2  1 
HETATM 4379 C C3  . BDF O  2 .  ? -22.38801 4.35594   -9.72922  1.000 9.74439  ? 101 BDF F C3  1 
HETATM 4380 C C4  . BDF O  2 .  ? -21.50914 4.24369   -8.48521  1.000 9.62758  ? 101 BDF F C4  1 
HETATM 4381 C C5  . BDF O  2 .  ? -22.08862 5.09679   -7.36636  1.000 9.01641  ? 101 BDF F C5  1 
HETATM 4382 C C6  . BDF O  2 .  ? -22.23318 6.52261   -7.85623  1.000 10.64136 ? 101 BDF F C6  1 
HETATM 4383 O O1  . BDF O  2 .  ? -23.60226 7.34139   -11.69127 1.000 18.40302 ? 101 BDF F O1  1 
HETATM 4384 O O2  . BDF O  2 .  ? -21.27620 6.30950   -10.50112 1.000 11.19478 ? 101 BDF F O2  1 
HETATM 4385 O O3  . BDF O  2 .  ? -21.83959 3.60896   -10.80636 1.000 9.87891  ? 101 BDF F O3  1 
HETATM 4386 O O4  . BDF O  2 .  ? -21.37119 2.88180   -8.09826  1.000 9.19426  ? 101 BDF F O4  1 
HETATM 4387 O O5  . BDF O  2 .  ? -23.39409 4.65086   -6.99637  1.000 9.09026  ? 101 BDF F O5  1 
HETATM 4388 O O6  . BDF O  2 .  ? -23.05747 6.57001   -9.02912  1.000 10.36558 ? 101 BDF F O6  1 
HETATM 4389 C C1  . BDF P  2 .  ? -12.52237 6.49962   3.54343   1.000 10.54110 ? 102 BDF F C1  1 
HETATM 4390 C C2  . BDF P  2 .  ? -12.86219 6.46627   5.02517   1.000 7.91359  ? 102 BDF F C2  1 
HETATM 4391 C C3  . BDF P  2 .  ? -13.00393 5.02471   5.53249   1.000 7.91242  ? 102 BDF F C3  1 
HETATM 4392 C C4  . BDF P  2 .  ? -13.52154 5.02230   6.96737   1.000 6.89176  ? 102 BDF F C4  1 
HETATM 4393 C C5  . BDF P  2 .  ? -14.82487 5.80487   7.04706   1.000 7.28549  ? 102 BDF F C5  1 
HETATM 4394 C C6  . BDF P  2 .  ? -14.59620 7.20162   6.50583   1.000 8.66549  ? 102 BDF F C6  1 
HETATM 4395 O O1  . BDF P  2 .  ? -12.27208 7.82295   3.09411   1.000 14.23263 ? 102 BDF F O1  1 
HETATM 4396 O O2  . BDF P  2 .  ? -11.88214 7.10957   5.79850   1.000 10.00438 ? 102 BDF F O2  1 
HETATM 4397 O O3  . BDF P  2 .  ? -11.77051 4.32289   5.42347   1.000 7.90206  ? 102 BDF F O3  1 
HETATM 4398 O O4  . BDF P  2 .  ? -13.67705 3.68285   7.42919   1.000 7.24940  ? 102 BDF F O4  1 
HETATM 4399 O O5  . BDF P  2 .  ? -15.84080 5.19272   6.25032   1.000 7.53129  ? 102 BDF F O5  1 
HETATM 4400 O O6  . BDF P  2 .  ? -14.10812 7.14409   5.15866   1.000 8.66693  ? 102 BDF F O6  1 
HETATM 4401 C C1  . BDF Q  2 .  ? -37.68185 8.40416   22.73860  1.000 10.54410 ? 101 BDF D C1  1 
HETATM 4402 C C2  . BDF Q  2 .  ? -38.86517 8.36312   21.78752  1.000 8.07362  ? 101 BDF D C2  1 
HETATM 4403 C C3  . BDF Q  2 .  ? -39.30648 6.91546   21.52934  1.000 8.90382  ? 101 BDF D C3  1 
HETATM 4404 C C4  . BDF Q  2 .  ? -40.34339 6.86969   20.41283  1.000 8.65695  ? 101 BDF D C4  1 
HETATM 4405 C C5  . BDF Q  2 .  ? -39.78407 7.53776   19.16666  1.000 8.31043  ? 101 BDF D C5  1 
HETATM 4406 C C6  . BDF Q  2 .  ? -39.37176 8.95172   19.51615  1.000 9.17664  ? 101 BDF D C6  1 
HETATM 4407 O O1  . BDF Q  2 .  ? -37.23248 9.73419   22.94800  1.000 15.23329 ? 101 BDF D O1  1 
HETATM 4408 O O2  . BDF Q  2 .  ? -39.95881 9.09068   22.28538  1.000 10.09080 ? 101 BDF D O2  1 
HETATM 4409 O O3  . BDF Q  2 .  ? -39.80685 6.32326   22.72237  1.000 8.67183  ? 101 BDF D O3  1 
HETATM 4410 O O4  . BDF Q  2 .  ? -40.73631 5.52529   20.14944  1.000 8.58142  ? 101 BDF D O4  1 
HETATM 4411 O O5  . BDF Q  2 .  ? -38.60745 6.86031   18.71999  1.000 8.05649  ? 101 BDF D O5  1 
HETATM 4412 O O6  . BDF Q  2 .  ? -38.40388 8.94760   20.57495  1.000 8.58365  ? 101 BDF D O6  1 
HETATM 4413 C C1  . BDF R  2 .  ? -19.66893 7.09677   21.07957  1.000 11.83387 ? 102 BDF D C1  1 
HETATM 4414 C C2  . BDF R  2 .  ? -21.15330 6.98908   21.39223  1.000 9.68253  ? 102 BDF D C2  1 
HETATM 4415 C C3  . BDF R  2 .  ? -21.62456 5.52964   21.44958  1.000 9.22638  ? 102 BDF D C3  1 
HETATM 4416 C C4  . BDF R  2 .  ? -23.13933 5.47367   21.58788  1.000 8.54099  ? 102 BDF D C4  1 
HETATM 4417 C C5  . BDF R  2 .  ? -23.78820 6.24799   20.45020  1.000 7.97964  ? 102 BDF D C5  1 
HETATM 4418 C C6  . BDF R  2 .  ? -23.24741 7.66326   20.43981  1.000 9.44085  ? 102 BDF D C6  1 
HETATM 4419 O O1  . BDF R  2 .  ? -19.21165 8.43464   21.20888  1.000 33.21059 ? 102 BDF D O1  1 
HETATM 4420 O O2  . BDF R  2 .  ? -21.46715 7.58493   22.62426  1.000 10.17916 ? 102 BDF D O2  1 
HETATM 4421 O O3  . BDF R  2 .  ? -21.01359 4.84703   22.53318  1.000 9.30569  ? 102 BDF D O3  1 
HETATM 4422 O O4  . BDF R  2 .  ? -23.57815 4.12270   21.63292  1.000 8.92648  ? 102 BDF D O4  1 
HETATM 4423 O O5  . BDF R  2 .  ? -23.48841 5.66758   19.18027  1.000 9.13348  ? 102 BDF D O5  1 
HETATM 4424 O O6  . BDF R  2 .  ? -21.81840 7.66197   20.32656  1.000 9.73739  ? 102 BDF D O6  1 
HETATM 4425 O O3  . T3Y S  3 .  ? -37.81722 -22.88006 12.18009  1.000 59.93702 ? 101 T3Y A O3  1 
HETATM 4426 S S1  . T3Y S  3 .  ? -37.71143 -22.15389 10.89268  1.000 71.15521 ? 101 T3Y A S1  1 
HETATM 4427 O O1  . T3Y S  3 .  ? -37.09107 -20.86812 11.08266  1.000 57.52418 ? 101 T3Y A O1  1 
HETATM 4428 O O2  . T3Y S  3 .  ? -38.98552 -22.10818 10.22231  1.000 56.32772 ? 101 T3Y A O2  1 
HETATM 4429 C C1  . T3Y S  3 .  ? -36.62289 -23.10409 9.86638   1.000 58.29166 ? 101 T3Y A C1  1 
HETATM 4430 C C24 . T3Y S  3 .  ? -35.59384 -23.83362 10.43811  1.000 41.07983 ? 101 T3Y A C24 1 
HETATM 4431 C C23 . T3Y S  3 .  ? -34.73166 -24.58072 9.64648   1.000 44.12736 ? 101 T3Y A C23 1 
HETATM 4432 C C22 . T3Y S  3 .  ? -33.60375 -25.37929 10.27412  1.000 40.53458 ? 101 T3Y A C22 1 
HETATM 4433 C C2  . T3Y S  3 .  ? -36.80993 -23.10919 8.49567   1.000 53.34258 ? 101 T3Y A C2  1 
HETATM 4434 C C3  . T3Y S  3 .  ? -35.97164 -23.84492 7.67091   1.000 51.74936 ? 101 T3Y A C3  1 
HETATM 4435 C C25 . T3Y S  3 .  ? -34.93167 -24.57818 8.25932   1.000 50.81524 ? 101 T3Y A C25 1 
HETATM 4436 O O13 . T3Y S  3 .  ? -34.09305 -25.30810 7.46821   1.000 49.30749 ? 101 T3Y A O13 1 
HETATM 4437 C C4  . T3Y S  3 .  ? -36.18543 -23.84190 6.16904   1.000 51.98989 ? 101 T3Y A C4  1 
HETATM 4438 C C5  . T3Y S  3 .  ? -35.46513 -22.68236 5.50627   1.000 52.18723 ? 101 T3Y A C5  1 
HETATM 4439 C C6  . T3Y S  3 .  ? -36.15277 -21.51994 5.18718   1.000 57.51071 ? 101 T3Y A C6  1 
HETATM 4440 C C7  . T3Y S  3 .  ? -35.50145 -20.45768 4.58526   1.000 62.84370 ? 101 T3Y A C7  1 
HETATM 4441 S S2  . T3Y S  3 .  ? -36.41197 -18.99288 4.17849   1.000 93.62975 ? 101 T3Y A S2  1 
HETATM 4442 O O4  . T3Y S  3 .  ? -36.92910 -19.18266 2.84765   1.000 81.52496 ? 101 T3Y A O4  1 
HETATM 4443 O O5  . T3Y S  3 .  ? -37.52085 -18.89910 5.15853   1.000 73.44300 ? 101 T3Y A O5  1 
HETATM 4444 O O6  . T3Y S  3 .  ? -35.50842 -17.88051 4.32039   1.000 76.09731 ? 101 T3Y A O6  1 
HETATM 4445 C C8  . T3Y S  3 .  ? -34.14961 -20.53458 4.29676   1.000 55.05841 ? 101 T3Y A C8  1 
HETATM 4446 C C28 . T3Y S  3 .  ? -34.09584 -22.74730 5.21395   1.000 50.35136 ? 101 T3Y A C28 1 
HETATM 4447 O O16 . T3Y S  3 .  ? -33.39486 -23.87530 5.52404   1.000 56.02288 ? 101 T3Y A O16 1 
HETATM 4448 C C9  . T3Y S  3 .  ? -33.42651 -21.68033 4.59928   1.000 56.15799 ? 101 T3Y A C9  1 
HETATM 4449 C C10 . T3Y S  3 .  ? -31.94159 -21.75419 4.29438   1.000 49.06843 ? 101 T3Y A C10 1 
HETATM 4450 C C11 . T3Y S  3 .  ? -31.11943 -21.43594 5.53078   1.000 62.22151 ? 101 T3Y A C11 1 
HETATM 4451 C C12 . T3Y S  3 .  ? -30.83718 -20.11726 5.85831   1.000 59.93686 ? 101 T3Y A C12 1 
HETATM 4452 C C13 . T3Y S  3 .  ? -30.08955 -19.81574 6.98311   1.000 56.95546 ? 101 T3Y A C13 1 
HETATM 4453 S S3  . T3Y S  3 .  ? -29.73600 -18.13024 7.38893   1.000 78.57090 ? 101 T3Y A S3  1 
HETATM 4454 O O7  . T3Y S  3 .  ? -30.93720 -17.37287 7.15323   1.000 61.25393 ? 101 T3Y A O7  1 
HETATM 4455 O O8  . T3Y S  3 .  ? -28.64785 -17.69825 6.47575   1.000 73.19535 ? 101 T3Y A O8  1 
HETATM 4456 O O9  . T3Y S  3 .  ? -29.34064 -18.12393 8.77327   1.000 73.63081 ? 101 T3Y A O9  1 
HETATM 4457 C C14 . T3Y S  3 .  ? -29.62355 -20.82063 7.81058   1.000 53.67222 ? 101 T3Y A C14 1 
HETATM 4458 C C27 . T3Y S  3 .  ? -30.64340 -22.44690 6.38003   1.000 57.89492 ? 101 T3Y A C27 1 
HETATM 4459 O O15 . T3Y S  3 .  ? -30.90690 -23.75332 6.09369   1.000 50.01064 ? 101 T3Y A O15 1 
HETATM 4460 C C15 . T3Y S  3 .  ? -29.89015 -22.15010 7.52521   1.000 57.62653 ? 101 T3Y A C15 1 
HETATM 4461 C C16 . T3Y S  3 .  ? -29.36820 -23.24055 8.44241   1.000 51.33702 ? 101 T3Y A C16 1 
HETATM 4462 C C17 . T3Y S  3 .  ? -30.30957 -23.51961 9.60006   1.000 50.46232 ? 101 T3Y A C17 1 
HETATM 4463 C C18 . T3Y S  3 .  ? -30.03226 -23.03810 10.87329  1.000 57.89679 ? 101 T3Y A C18 1 
HETATM 4464 C C26 . T3Y S  3 .  ? -31.46779 -24.28622 9.41634   1.000 50.91749 ? 101 T3Y A C26 1 
HETATM 4465 O O14 . T3Y S  3 .  ? -31.74817 -24.76296 8.16965   1.000 38.32415 ? 101 T3Y A O14 1 
HETATM 4466 C C21 . T3Y S  3 .  ? -32.34627 -24.55378 10.47567  1.000 47.77450 ? 101 T3Y A C21 1 
HETATM 4467 C C20 . T3Y S  3 .  ? -32.03516 -24.05336 11.73158  1.000 46.01430 ? 101 T3Y A C20 1 
HETATM 4468 C C19 . T3Y S  3 .  ? -30.89181 -23.29920 11.92777  1.000 55.86739 ? 101 T3Y A C19 1 
HETATM 4469 S S4  . T3Y S  3 .  ? -30.52469 -22.67662 13.54596  1.000 62.04757 ? 101 T3Y A S4  1 
HETATM 4470 O O11 . T3Y S  3 .  ? -30.20777 -23.81536 14.36907  1.000 56.05269 ? 101 T3Y A O11 1 
HETATM 4471 O O10 . T3Y S  3 .  ? -29.34097 -21.79714 13.40093  1.000 64.20252 ? 101 T3Y A O10 1 
HETATM 4472 O O12 . T3Y S  3 .  ? -31.67332 -21.92069 13.97401  1.000 55.80771 ? 101 T3Y A O12 1 
HETATM 4473 C C1  . BDF T  2 .  ? -49.86695 7.80818   8.12031   1.000 10.01119 ? 102 BDF A C1  1 
HETATM 4474 C C2  . BDF T  2 .  ? -49.40968 7.54547   6.69657   1.000 8.03513  ? 102 BDF A C2  1 
HETATM 4475 C C3  . BDF T  2 .  ? -49.24382 6.04659   6.41901   1.000 8.50637  ? 102 BDF A C3  1 
HETATM 4476 C C4  . BDF T  2 .  ? -48.62411 5.84055   5.04400   1.000 9.21574  ? 102 BDF A C4  1 
HETATM 4477 C C5  . BDF T  2 .  ? -47.30005 6.58629   4.95739   1.000 8.32167  ? 102 BDF A C5  1 
HETATM 4478 C C6  . BDF T  2 .  ? -47.52946 8.04637   5.28971   1.000 9.24994  ? 102 BDF A C6  1 
HETATM 4479 O O1  . BDF T  2 .  ? -51.15522 7.26062   8.35657   1.000 12.76582 ? 102 BDF A O1  1 
HETATM 4480 O O2  . BDF T  2 .  ? -50.31817 8.06314   5.75905   1.000 10.10620 ? 102 BDF A O2  1 
HETATM 4481 O O3  . BDF T  2 .  ? -50.49739 5.38726   6.48370   1.000 9.32614  ? 102 BDF A O3  1 
HETATM 4482 O O4  . BDF T  2 .  ? -48.47697 4.45092   4.77981   1.000 8.48751  ? 102 BDF A O4  1 
HETATM 4483 O O5  . BDF T  2 .  ? -46.34823 6.07111   5.88882   1.000 8.55625  ? 102 BDF A O5  1 
HETATM 4484 O O6  . BDF T  2 .  ? -48.14677 8.19162   6.57716   1.000 8.85504  ? 102 BDF A O6  1 
HETATM 4485 C C1  . BDF U  2 .  ? -42.34973 7.33051   -8.97548  1.000 11.48791 ? 103 BDF A C1  1 
HETATM 4486 C C2  . BDF U  2 .  ? -40.88285 7.14678   -9.32589  1.000 9.36023  ? 103 BDF A C2  1 
HETATM 4487 C C3  . BDF U  2 .  ? -40.49188 5.66481   -9.36481  1.000 8.54052  ? 103 BDF A C3  1 
HETATM 4488 C C4  . BDF U  2 .  ? -38.98657 5.52563   -9.55176  1.000 8.96601  ? 103 BDF A C4  1 
HETATM 4489 C C5  . BDF U  2 .  ? -38.25659 6.28964   -8.45624  1.000 8.76381  ? 103 BDF A C5  1 
HETATM 4490 C C6  . BDF U  2 .  ? -38.72135 7.73295   -8.46224  1.000 9.94717  ? 103 BDF A C6  1 
HETATM 4491 O O1  . BDF U  2 .  ? -42.77074 8.65979   -9.23591  1.000 15.12574 ? 103 BDF A O1  1 
HETATM 4492 O O2  . BDF U  2 .  ? -40.58407 7.70185   -10.57640 1.000 10.55684 ? 103 BDF A O2  1 
HETATM 4493 O O3  . BDF U  2 .  ? -41.18287 5.01024   -10.41926 1.000 9.83429  ? 103 BDF A O3  1 
HETATM 4494 O O4  . BDF U  2 .  ? -38.62573 4.14909   -9.58313  1.000 8.70373  ? 103 BDF A O4  1 
HETATM 4495 O O5  . BDF U  2 .  ? -38.55055 5.73717   -7.17229  1.000 8.04312  ? 103 BDF A O5  1 
HETATM 4496 O O6  . BDF U  2 .  ? -40.14532 7.81232   -8.30421  1.000 9.25401  ? 103 BDF A O6  1 
HETATM 4497 O O   . HOH V  4 .  ? -29.36299 4.61405   -18.99685 1.000 29.45761 ? 201 HOH B O   1 
HETATM 4498 O O   . HOH V  4 .  ? -33.54092 8.47174   -19.66912 0.666 18.85407 ? 202 HOH B O   1 
HETATM 4499 O O   . HOH V  4 .  ? -28.40425 -4.58629  -41.01705 1.000 30.57535 ? 203 HOH B O   1 
HETATM 4500 O O   . HOH V  4 .  ? -21.29855 21.94822  -34.87677 1.000 30.25313 ? 204 HOH B O   1 
HETATM 4501 O O   . HOH V  4 .  ? -21.73609 18.07140  -39.63438 1.000 30.73112 ? 205 HOH B O   1 
HETATM 4502 O O   . HOH V  4 .  ? -26.53608 6.19358   -41.68377 1.000 19.78516 ? 206 HOH B O   1 
HETATM 4503 O O   . HOH V  4 .  ? -13.27350 14.48887  -25.86677 1.000 20.25776 ? 207 HOH B O   1 
HETATM 4504 O O   . HOH V  4 .  ? -26.57749 -4.54520  -29.95963 1.000 11.56848 ? 208 HOH B O   1 
HETATM 4505 O O   . HOH V  4 .  ? -21.44342 15.60401  -30.97334 1.000 30.96896 ? 209 HOH B O   1 
HETATM 4506 O O   . HOH V  4 .  ? -16.82956 -16.93216 -29.36475 1.000 37.51967 ? 210 HOH B O   1 
HETATM 4507 O O   . HOH V  4 .  ? -25.94787 -8.21277  -45.12861 1.000 37.87155 ? 211 HOH B O   1 
HETATM 4508 O O   . HOH V  4 .  ? -22.58483 -6.59329  -26.13335 1.000 18.82078 ? 212 HOH B O   1 
HETATM 4509 O O   . HOH V  4 .  ? -11.36506 9.83947   -36.11695 1.000 13.41673 ? 213 HOH B O   1 
HETATM 4510 O O   . HOH V  4 .  ? -25.91283 12.61352  -22.53122 1.000 21.46807 ? 214 HOH B O   1 
HETATM 4511 O O   . HOH V  4 .  ? -12.26487 -14.72572 -23.56804 1.000 32.97589 ? 215 HOH B O   1 
HETATM 4512 O O   . HOH V  4 .  ? -22.410   12.550    -26.132   1.000 17.44864 ? 216 HOH B O   1 
HETATM 4513 O O   . HOH V  4 .  ? -30.22183 1.72921   -41.88587 1.000 24.93780 ? 217 HOH B O   1 
HETATM 4514 O O   . HOH V  4 .  ? -18.50520 -10.12497 -43.11399 1.000 13.87622 ? 218 HOH B O   1 
HETATM 4515 O O   . HOH V  4 .  ? -12.03872 4.87804   -31.89839 1.000 18.99043 ? 219 HOH B O   1 
HETATM 4516 O O   . HOH V  4 .  ? -13.13873 -7.22069  -38.28769 1.000 8.46834  ? 220 HOH B O   1 
HETATM 4517 O O   . HOH V  4 .  ? -18.93815 -10.69173 -40.43237 1.000 16.20565 ? 221 HOH B O   1 
HETATM 4518 O O   . HOH V  4 .  ? -19.19665 16.42689  -25.67104 1.000 32.62718 ? 222 HOH B O   1 
HETATM 4519 O O   . HOH V  4 .  ? -16.78400 -6.47080  -48.01045 1.000 17.13652 ? 223 HOH B O   1 
HETATM 4520 O O   . HOH V  4 .  ? -26.85699 -3.39897  -37.23578 1.000 26.73017 ? 224 HOH B O   1 
HETATM 4521 O O   . HOH V  4 .  ? -14.43632 9.61001   -32.06734 1.000 12.23801 ? 225 HOH B O   1 
HETATM 4522 O O   . HOH V  4 .  ? -26.00361 6.69400   -20.88349 1.000 9.89978  ? 226 HOH B O   1 
HETATM 4523 O O   . HOH V  4 .  ? -20.45030 -4.79941  -26.01643 1.000 10.34620 ? 227 HOH B O   1 
HETATM 4524 O O   . HOH V  4 .  ? -10.59466 -12.88357 -28.32672 1.000 26.65882 ? 228 HOH B O   1 
HETATM 4525 O O   . HOH V  4 .  ? -31.46046 12.55714  -18.77285 1.000 35.63119 ? 229 HOH B O   1 
HETATM 4526 O O   . HOH V  4 .  ? -29.24622 2.26747   -19.00595 0.605 15.25850 ? 230 HOH B O   1 
HETATM 4527 O O   . HOH V  4 .  ? -18.83839 4.85643   -50.56272 1.000 12.12103 ? 231 HOH B O   1 
HETATM 4528 O O   . HOH V  4 .  ? -19.67085 9.80208   -18.48309 1.000 20.69459 ? 232 HOH B O   1 
HETATM 4529 O O   . HOH V  4 .  ? -13.30700 -9.01436  -46.97327 1.000 18.78408 ? 233 HOH B O   1 
HETATM 4530 O O   . HOH V  4 .  ? -24.878   0.717     -49.130   1.000 17.78307 ? 234 HOH B O   1 
HETATM 4531 O O   . HOH V  4 .  ? -30.69377 6.87977   -17.06370 1.000 30.39802 ? 235 HOH B O   1 
HETATM 4532 O O   . HOH V  4 .  ? -14.14991 -1.20101  -51.95211 1.000 9.53969  ? 236 HOH B O   1 
HETATM 4533 O O   . HOH V  4 .  ? -27.21739 -1.15313  -46.00751 1.000 27.18211 ? 237 HOH B O   1 
HETATM 4534 O O   . HOH V  4 .  ? -12.00207 -11.06807 -48.73882 1.000 30.15141 ? 238 HOH B O   1 
HETATM 4535 O O   . HOH V  4 .  ? -9.50537  6.68593   -35.21582 0.452 15.73788 ? 239 HOH B O   1 
HETATM 4536 O O   . HOH V  4 .  ? -10.27407 4.97517   -34.06172 0.633 21.08969 ? 240 HOH B O   1 
HETATM 4537 O O   . HOH V  4 .  ? -17.21508 -15.64335 -32.44789 1.000 24.48327 ? 241 HOH B O   1 
HETATM 4538 O O   . HOH V  4 .  ? -22.01800 3.24586   -47.35726 0.415 13.96239 ? 242 HOH B O   1 
HETATM 4539 O O   . HOH V  4 .  ? -17.18662 16.40063  -19.02194 1.000 36.89544 ? 243 HOH B O   1 
HETATM 4540 O O   . HOH V  4 .  ? -22.14777 -10.43226 -28.85795 1.000 17.70610 ? 244 HOH B O   1 
HETATM 4541 O O   . HOH V  4 .  ? -23.15574 -12.48164 -29.34452 1.000 32.13166 ? 245 HOH B O   1 
HETATM 4542 O O   . HOH V  4 .  ? -22.07146 15.27175  -40.69161 1.000 28.77010 ? 246 HOH B O   1 
HETATM 4543 O O   . HOH V  4 .  ? -21.49930 -8.24896  -40.72225 1.000 14.55601 ? 247 HOH B O   1 
HETATM 4544 O O   . HOH V  4 .  ? -18.51484 -3.53161  -46.72538 1.000 11.82600 ? 248 HOH B O   1 
HETATM 4545 O O   . HOH V  4 .  ? -19.666   8.779     -49.517   1.000 35.99125 ? 249 HOH B O   1 
HETATM 4546 O O   . HOH V  4 .  ? -29.19666 -2.79816  -20.21073 1.000 19.82988 ? 250 HOH B O   1 
HETATM 4547 O O   . HOH V  4 .  ? -20.70329 -14.70011 -38.34752 1.000 25.38704 ? 251 HOH B O   1 
HETATM 4548 O O   . HOH V  4 .  ? -30.67374 -1.82411  -23.04662 0.814 16.82210 ? 252 HOH B O   1 
HETATM 4549 O O   . HOH V  4 .  ? -10.90875 2.24779   -32.01501 1.000 21.75816 ? 253 HOH B O   1 
HETATM 4550 O O   . HOH V  4 .  ? -10.06385 -3.83572  -30.17072 1.000 14.53651 ? 254 HOH B O   1 
HETATM 4551 O O   . HOH V  4 .  ? -11.21635 -0.36485  -30.27276 1.000 10.85804 ? 255 HOH B O   1 
HETATM 4552 O O   . HOH V  4 .  ? -30.65710 -3.88344  -30.78778 1.000 20.50443 ? 256 HOH B O   1 
HETATM 4553 O O   . HOH V  4 .  ? -18.32665 -17.85012 -25.90838 1.000 35.07702 ? 257 HOH B O   1 
HETATM 4554 O O   . HOH V  4 .  ? -27.62589 7.89154   -22.70868 1.000 20.41671 ? 258 HOH B O   1 
HETATM 4555 O O   . HOH V  4 .  ? -15.41449 -13.76580 -31.14897 1.000 28.61940 ? 259 HOH B O   1 
HETATM 4556 O O   . HOH V  4 .  ? -18.67942 -3.03143  -51.27671 1.000 17.19189 ? 260 HOH B O   1 
HETATM 4557 O O   . HOH V  4 .  ? -24.34014 12.18604  -43.07381 1.000 30.41816 ? 261 HOH B O   1 
HETATM 4558 O O   . HOH V  4 .  ? -19.81288 13.40942  -25.60248 1.000 15.21370 ? 262 HOH B O   1 
HETATM 4559 O O   . HOH V  4 .  ? -29.79901 0.85676   -37.77952 1.000 17.95217 ? 263 HOH B O   1 
HETATM 4560 O O   . HOH V  4 .  ? -19.34680 -7.63883  -47.30452 1.000 24.23632 ? 264 HOH B O   1 
HETATM 4561 O O   . HOH V  4 .  ? -22.30539 -8.87425  -45.03519 1.000 22.24131 ? 265 HOH B O   1 
HETATM 4562 O O   . HOH V  4 .  ? -17.49582 12.22758  -43.15066 1.000 18.29950 ? 266 HOH B O   1 
HETATM 4563 O O   . HOH V  4 .  ? -14.51723 -7.74914  -49.12746 1.000 16.23752 ? 267 HOH B O   1 
HETATM 4564 O O   . HOH V  4 .  ? -14.37271 13.58995  -29.73743 1.000 14.18714 ? 268 HOH B O   1 
HETATM 4565 O O   . HOH V  4 .  ? -30.32409 3.54136   -33.16665 1.000 24.05523 ? 269 HOH B O   1 
HETATM 4566 O O   . HOH V  4 .  ? -24.07045 -14.91034 -36.96512 1.000 31.18729 ? 270 HOH B O   1 
HETATM 4567 O O   . HOH V  4 .  ? -27.67262 -3.03899  -18.00051 1.000 20.18990 ? 271 HOH B O   1 
HETATM 4568 O O   . HOH V  4 .  ? -11.42679 -5.79443  -53.16615 1.000 27.69608 ? 272 HOH B O   1 
HETATM 4569 O O   . HOH V  4 .  ? -18.62316 9.35170   -47.61411 1.000 36.80342 ? 273 HOH B O   1 
HETATM 4570 O O   . HOH V  4 .  ? -24.252   12.952    -33.849   1.000 26.84921 ? 274 HOH B O   1 
HETATM 4571 O O   . HOH V  4 .  ? -15.25467 -15.79133 -45.75422 1.000 23.10924 ? 275 HOH B O   1 
HETATM 4572 O O   . HOH V  4 .  ? -12.11629 6.62389   -33.42174 1.000 29.38309 ? 276 HOH B O   1 
HETATM 4573 O O   . HOH V  4 .  ? -13.31799 13.47109  -34.43593 1.000 15.87782 ? 277 HOH B O   1 
HETATM 4574 O O   . HOH V  4 .  ? -11.64813 -12.11040 -33.19420 1.000 15.87823 ? 278 HOH B O   1 
HETATM 4575 O O   . HOH V  4 .  ? -25.49967 -5.51691  -26.31677 0.482 18.10511 ? 279 HOH B O   1 
HETATM 4576 O O   . HOH V  4 .  ? -28.21626 -6.73472  -29.60350 1.000 20.71584 ? 280 HOH B O   1 
HETATM 4577 O O   . HOH V  4 .  ? -11.14953 -1.27710  -32.89237 1.000 10.77546 ? 281 HOH B O   1 
HETATM 4578 O O   . HOH V  4 .  ? -8.59083  -7.27667  -31.27309 1.000 12.62993 ? 282 HOH B O   1 
HETATM 4579 O O   . HOH V  4 .  ? -25.88332 -9.10825  -42.22325 1.000 29.08438 ? 283 HOH B O   1 
HETATM 4580 O O   . HOH V  4 .  ? -20.11746 9.28494   -45.27381 1.000 28.53731 ? 284 HOH B O   1 
HETATM 4581 O O   . HOH V  4 .  ? -10.23920 -3.98073  -32.88593 1.000 15.54073 ? 285 HOH B O   1 
HETATM 4582 O O   . HOH V  4 .  ? -17.28158 -16.53205 -44.26954 1.000 35.99692 ? 286 HOH B O   1 
HETATM 4583 O O   . HOH V  4 .  ? -11.94544 8.76750   -32.32903 1.000 20.53944 ? 287 HOH B O   1 
HETATM 4584 O O   . HOH V  4 .  ? -29.09230 -1.71054  -37.23409 1.000 22.15534 ? 288 HOH B O   1 
HETATM 4585 O O   . HOH V  4 .  ? -23.18273 19.23153  -37.42749 1.000 29.07381 ? 289 HOH B O   1 
HETATM 4586 O O   . HOH V  4 .  ? -11.41945 8.78042   -30.10263 1.000 25.90484 ? 290 HOH B O   1 
HETATM 4587 O O   . HOH V  4 .  ? -18.73319 -5.51531  -49.99137 1.000 24.57256 ? 291 HOH B O   1 
HETATM 4588 O O   . HOH V  4 .  ? -16.76515 10.36785  -17.64817 1.000 28.37679 ? 292 HOH B O   1 
HETATM 4589 O O   . HOH V  4 .  ? -35.53713 10.14263  -20.22393 1.000 17.52348 ? 293 HOH B O   1 
HETATM 4590 O O   . HOH V  4 .  ? -31.20232 5.28371   -27.21943 1.000 18.23834 ? 294 HOH B O   1 
HETATM 4591 O O   . HOH V  4 .  ? -21.97390 11.17691  -44.37468 1.000 34.71907 ? 295 HOH B O   1 
HETATM 4592 O O   . HOH V  4 .  ? -12.88087 12.59732  -27.90266 1.000 23.42612 ? 296 HOH B O   1 
HETATM 4593 O O   . HOH V  4 .  ? -19.15924 15.59741  -29.46150 1.000 24.08365 ? 297 HOH B O   1 
HETATM 4594 O O   . HOH V  4 .  ? -12.21151 16.91735  -36.93233 1.000 32.16975 ? 298 HOH B O   1 
HETATM 4595 O O   . HOH V  4 .  ? -19.77207 13.46433  -44.02282 1.000 30.25052 ? 299 HOH B O   1 
HETATM 4596 O O   . HOH V  4 .  ? -21.01658 -11.08702 -46.60829 1.000 30.03710 ? 300 HOH B O   1 
HETATM 4597 O O   . HOH V  4 .  ? -21.338   24.250    -33.116   1.000 27.83875 ? 301 HOH B O   1 
HETATM 4598 O O   . HOH V  4 .  ? -14.52783 16.31534  -29.67172 1.000 23.24535 ? 302 HOH B O   1 
HETATM 4599 O O   . HOH V  4 .  ? -19.99679 -12.18742 -44.32298 1.000 21.35576 ? 303 HOH B O   1 
HETATM 4600 O O   . HOH V  4 .  ? -22.98041 -9.72119  -42.62029 1.000 18.54909 ? 304 HOH B O   1 
HETATM 4601 O O   . HOH V  4 .  ? -23.25898 5.22611   -48.92772 0.675 17.19535 ? 305 HOH B O   1 
HETATM 4602 O O   . HOH V  4 .  ? -13.86195 12.26552  -32.20025 1.000 18.64537 ? 306 HOH B O   1 
HETATM 4603 O O   . HOH V  4 .  ? -29.082   13.396    -19.844   1.000 34.16772 ? 307 HOH B O   1 
HETATM 4604 O O   . HOH V  4 .  ? -29.97968 9.20954   -15.40632 0.883 18.56432 ? 308 HOH B O   1 
HETATM 4605 O O   . HOH V  4 .  ? -25.36009 14.73333  -20.85033 1.000 38.11290 ? 309 HOH B O   1 
HETATM 4606 O O   . HOH V  4 .  ? -17.20779 17.35853  -29.54403 1.000 25.60238 ? 310 HOH B O   1 
HETATM 4607 O O   . HOH V  4 .  ? -30.81095 -5.97294  -29.27501 1.000 28.68162 ? 311 HOH B O   1 
HETATM 4608 O O   . HOH V  4 .  ? -12.81482 16.13973  -34.00025 1.000 27.70289 ? 312 HOH B O   1 
HETATM 4609 O O   . HOH V  4 .  ? -20.00267 -9.96907  -48.61403 1.000 35.74310 ? 313 HOH B O   1 
HETATM 4610 O O   . HOH V  4 .  ? -27.12422 -11.35865 -41.62485 1.000 33.71455 ? 314 HOH B O   1 
HETATM 4611 O O   . HOH V  4 .  ? -19.124   24.012    -31.115   1.000 35.60473 ? 315 HOH B O   1 
HETATM 4612 O O   . HOH V  4 .  ? -13.43764 17.50630  -31.87925 1.000 34.30717 ? 316 HOH B O   1 
HETATM 4613 O O   . HOH W  4 .  ? -10.65909 -15.93554 -21.53629 1.000 22.75125 ? 201 HOH C O   1 
HETATM 4614 O O   . HOH W  4 .  ? -7.50724  20.41956  -18.80385 1.000 25.96508 ? 202 HOH C O   1 
HETATM 4615 O O   . HOH W  4 .  ? 4.12942   -29.01151 -23.63120 1.000 17.30750 ? 203 HOH C O   1 
HETATM 4616 O O   . HOH W  4 .  ? -8.42786  19.00868  -25.51688 1.000 32.73356 ? 204 HOH C O   1 
HETATM 4617 O O   . HOH W  4 .  ? -3.18849  15.07507  -31.97825 1.000 24.54767 ? 205 HOH C O   1 
HETATM 4618 O O   . HOH W  4 .  ? 1.05783   -9.25965  -14.48448 1.000 36.44645 ? 206 HOH C O   1 
HETATM 4619 O O   . HOH W  4 .  ? -2.13753  -20.48773 -18.54090 0.682 17.91865 ? 207 HOH C O   1 
HETATM 4620 O O   . HOH W  4 .  ? -3.89805  -13.20004 -21.54399 0.533 14.19852 ? 208 HOH C O   1 
HETATM 4621 O O   . HOH W  4 .  ? -5.69810  -20.49277 -18.77816 1.000 32.52449 ? 209 HOH C O   1 
HETATM 4622 O O   . HOH W  4 .  ? -12.13451 -7.14685  -24.13585 1.000 10.73846 ? 210 HOH C O   1 
HETATM 4623 O O   . HOH W  4 .  ? -11.03530 -9.73560  -17.68532 1.000 19.79585 ? 211 HOH C O   1 
HETATM 4624 O O   . HOH W  4 .  ? -8.80803  7.67737   -11.80896 1.000 15.18772 ? 212 HOH C O   1 
HETATM 4625 O O   . HOH W  4 .  ? -11.07039 5.48341   -29.44114 1.000 22.87729 ? 213 HOH C O   1 
HETATM 4626 O O   . HOH W  4 .  ? 1.49917   -2.44264  -16.58977 1.000 9.02646  ? 214 HOH C O   1 
HETATM 4627 O O   . HOH W  4 .  ? -15.81343 9.72594   -15.24180 1.000 27.67546 ? 215 HOH C O   1 
HETATM 4628 O O   . HOH W  4 .  ? 1.26161   14.01309  -23.82562 1.000 17.99914 ? 216 HOH C O   1 
HETATM 4629 O O   . HOH W  4 .  ? -19.00681 -6.21902  -16.48806 1.000 15.59808 ? 217 HOH C O   1 
HETATM 4630 O O   . HOH W  4 .  ? 1.73733   10.49175  -18.07249 1.000 21.43964 ? 218 HOH C O   1 
HETATM 4631 O O   . HOH W  4 .  ? 2.88996   -4.57097  -21.47255 1.000 13.90683 ? 219 HOH C O   1 
HETATM 4632 O O   . HOH W  4 .  ? -18.64398 -7.15546  -23.56354 1.000 14.34656 ? 220 HOH C O   1 
HETATM 4633 O O   . HOH W  4 .  ? 12.49857  3.17314   -22.76004 1.000 16.50716 ? 221 HOH C O   1 
HETATM 4634 O O   . HOH W  4 .  ? -13.60383 -8.35190  -13.10487 1.000 29.69585 ? 222 HOH C O   1 
HETATM 4635 O O   . HOH W  4 .  ? -3.98962  -16.72103 -20.61422 0.650 27.20241 ? 223 HOH C O   1 
HETATM 4636 O O   . HOH W  4 .  ? -5.29315  -13.97179 -14.77783 1.000 15.90745 ? 224 HOH C O   1 
HETATM 4637 O O   . HOH W  4 .  ? 8.27898   -3.44901  -16.87097 1.000 26.69160 ? 225 HOH C O   1 
HETATM 4638 O O   . HOH W  4 .  ? -5.03646  -1.58402  -13.16513 1.000 19.42666 ? 226 HOH C O   1 
HETATM 4639 O O   . HOH W  4 .  ? -12.41578 9.85594   -27.88771 1.000 12.94721 ? 227 HOH C O   1 
HETATM 4640 O O   . HOH W  4 .  ? 6.28533   15.59094  -30.78308 1.000 28.95231 ? 228 HOH C O   1 
HETATM 4641 O O   . HOH W  4 .  ? 7.98172   9.12973   -22.67846 1.000 10.91703 ? 229 HOH C O   1 
HETATM 4642 O O   . HOH W  4 .  ? 5.54826   -20.72031 -33.43310 1.000 20.13454 ? 230 HOH C O   1 
HETATM 4643 O O   . HOH W  4 .  ? -6.36347  12.72548  -16.40520 1.000 25.62501 ? 231 HOH C O   1 
HETATM 4644 O O   . HOH W  4 .  ? -20.95743 5.26559   -13.87170 0.480 15.77796 ? 232 HOH C O   1 
HETATM 4645 O O   . HOH W  4 .  ? 3.46561   -19.63217 -26.65478 1.000 16.65640 ? 233 HOH C O   1 
HETATM 4646 O O   . HOH W  4 .  ? 9.13459   14.38553  -27.74994 1.000 31.32589 ? 234 HOH C O   1 
HETATM 4647 O O   . HOH W  4 .  ? -7.56684  9.92839   -27.25123 1.000 10.88111 ? 235 HOH C O   1 
HETATM 4648 O O   . HOH W  4 .  ? 0.84071   -8.61223  -20.31419 1.000 16.11352 ? 236 HOH C O   1 
HETATM 4649 O O   . HOH W  4 .  ? -7.50261  2.61832   -8.00809  1.000 22.37106 ? 237 HOH C O   1 
HETATM 4650 O O   . HOH W  4 .  ? 1.90718   -3.22706  -23.78323 1.000 9.82228  ? 238 HOH C O   1 
HETATM 4651 O O   . HOH W  4 .  ? -8.34554  5.15906   -29.03613 1.000 20.86774 ? 239 HOH C O   1 
HETATM 4652 O O   . HOH W  4 .  ? 0.32271   10.07563  -14.32063 1.000 26.52336 ? 240 HOH C O   1 
HETATM 4653 O O   . HOH W  4 .  ? -17.79411 -13.59119 -14.42486 1.000 33.91775 ? 241 HOH C O   1 
HETATM 4654 O O   . HOH W  4 .  ? -10.20641 -7.48104  -15.59087 1.000 13.77415 ? 242 HOH C O   1 
HETATM 4655 O O   . HOH W  4 .  ? 0.54013   -1.85300  -11.40138 1.000 16.41345 ? 243 HOH C O   1 
HETATM 4656 O O   . HOH W  4 .  ? -7.94317  -13.58739 -17.93187 1.000 17.73730 ? 244 HOH C O   1 
HETATM 4657 O O   . HOH W  4 .  ? -13.65220 -9.61022  -16.92241 1.000 15.99287 ? 245 HOH C O   1 
HETATM 4658 O O   . HOH W  4 .  ? -12.29328 -0.34352  -8.59278  1.000 29.52671 ? 246 HOH C O   1 
HETATM 4659 O O   . HOH W  4 .  ? 0.53798   -12.73767 -30.92198 0.557 12.60221 ? 247 HOH C O   1 
HETATM 4660 O O   . HOH W  4 .  ? -1.82854  -16.00416 -23.33983 1.000 16.83342 ? 248 HOH C O   1 
HETATM 4661 O O   . HOH W  4 .  ? -24.07180 -1.53311  -16.81225 1.000 10.76571 ? 249 HOH C O   1 
HETATM 4662 O O   . HOH W  4 .  ? -9.82300  -6.80217  -28.74364 1.000 12.53075 ? 250 HOH C O   1 
HETATM 4663 O O   . HOH W  4 .  ? -2.07270  -19.68576 -28.26672 1.000 23.36206 ? 251 HOH C O   1 
HETATM 4664 O O   . HOH W  4 .  ? -3.70028  14.30868  -18.92804 1.000 30.85826 ? 252 HOH C O   1 
HETATM 4665 O O   . HOH W  4 .  ? -3.57788  -0.28319  -11.53107 1.000 20.12692 ? 253 HOH C O   1 
HETATM 4666 O O   . HOH W  4 .  ? 7.42743   -20.09619 -28.00742 1.000 25.82437 ? 254 HOH C O   1 
HETATM 4667 O O   . HOH W  4 .  ? -25.89984 -6.58546  -21.69196 1.000 37.09492 ? 255 HOH C O   1 
HETATM 4668 O O   . HOH W  4 .  ? 7.27306   -20.67779 -25.29866 1.000 31.82468 ? 256 HOH C O   1 
HETATM 4669 O O   . HOH W  4 .  ? 14.62912  10.04499  -23.23403 1.000 31.14816 ? 257 HOH C O   1 
HETATM 4670 O O   . HOH W  4 .  ? -3.46584  11.11957  -16.16247 1.000 22.93030 ? 258 HOH C O   1 
HETATM 4671 O O   . HOH W  4 .  ? 1.18440   -10.67636 -18.95413 0.452 12.18079 ? 259 HOH C O   1 
HETATM 4672 O O   . HOH W  4 .  ? -3.21816  -18.99135 -26.08214 1.000 19.00305 ? 260 HOH C O   1 
HETATM 4673 O O   . HOH W  4 .  ? 7.78151   2.19043   -15.19497 1.000 12.70881 ? 261 HOH C O   1 
HETATM 4674 O O   . HOH W  4 .  ? 0.37000   5.82739   -12.57700 1.000 12.83574 ? 262 HOH C O   1 
HETATM 4675 O O   . HOH W  4 .  ? -19.54982 -9.14755  -19.75891 1.000 18.47363 ? 263 HOH C O   1 
HETATM 4676 O O   . HOH W  4 .  ? -6.16944  -17.12150 -18.89623 1.000 29.59820 ? 264 HOH C O   1 
HETATM 4677 O O   . HOH W  4 .  ? 0.63414   -19.06887 -28.61363 1.000 24.92925 ? 265 HOH C O   1 
HETATM 4678 O O   . HOH W  4 .  ? -17.15333 -3.16845  -15.55942 1.000 10.29615 ? 266 HOH C O   1 
HETATM 4679 O O   . HOH W  4 .  ? 6.19655   10.63339  -18.44821 1.000 27.92543 ? 267 HOH C O   1 
HETATM 4680 O O   . HOH W  4 .  ? 4.58715   -18.59155 -30.35936 1.000 27.43156 ? 268 HOH C O   1 
HETATM 4681 O O   . HOH W  4 .  ? 3.38507   8.68309   -13.87557 1.000 23.82201 ? 269 HOH C O   1 
HETATM 4682 O O   . HOH W  4 .  ? 0.20123   14.60497  -26.30589 1.000 13.68539 ? 270 HOH C O   1 
HETATM 4683 O O   . HOH W  4 .  ? -6.71301  -0.15213  -30.23538 1.000 9.27563  ? 271 HOH C O   1 
HETATM 4684 O O   . HOH W  4 .  ? -20.01075 -4.69428  -12.59227 1.000 31.35613 ? 272 HOH C O   1 
HETATM 4685 O O   . HOH W  4 .  ? -1.990    10.198    -11.110   1.000 31.71195 ? 273 HOH C O   1 
HETATM 4686 O O   . HOH W  4 .  ? 11.99002  0.26151   -21.99036 0.472 11.72149 ? 274 HOH C O   1 
HETATM 4687 O O   . HOH W  4 .  ? -10.71898 18.50112  -17.15987 1.000 32.27990 ? 275 HOH C O   1 
HETATM 4688 O O   . HOH W  4 .  ? -11.07500 6.39756   -12.24896 1.000 28.81661 ? 276 HOH C O   1 
HETATM 4689 O O   . HOH W  4 .  ? -3.10348  22.34052  -19.29742 1.000 27.38347 ? 277 HOH C O   1 
HETATM 4690 O O   . HOH W  4 .  ? -8.80419  2.48745   -29.86153 1.000 22.65691 ? 278 HOH C O   1 
HETATM 4691 O O   . HOH W  4 .  ? -6.06086  13.92910  -28.91778 1.000 11.12725 ? 279 HOH C O   1 
HETATM 4692 O O   . HOH W  4 .  ? 7.25068   -23.42086 -21.65313 1.000 22.69453 ? 280 HOH C O   1 
HETATM 4693 O O   . HOH W  4 .  ? -10.40951 13.68511  -27.02719 1.000 13.90091 ? 281 HOH C O   1 
HETATM 4694 O O   . HOH W  4 .  ? 6.01067   -18.75698 -21.13575 1.000 35.96195 ? 282 HOH C O   1 
HETATM 4695 O O   . HOH W  4 .  ? -17.20706 -7.20061  -14.28345 1.000 24.20318 ? 283 HOH C O   1 
HETATM 4696 O O   . HOH W  4 .  ? -7.38682  -4.00443  -30.12617 1.000 17.21190 ? 284 HOH C O   1 
HETATM 4697 O O   . HOH W  4 .  ? -7.82892  -11.78692 -27.22822 1.000 18.16979 ? 285 HOH C O   1 
HETATM 4698 O O   . HOH W  4 .  ? -15.12935 0.95209   -8.62013  0.741 10.90757 ? 286 HOH C O   1 
HETATM 4699 O O   . HOH W  4 .  ? -0.87323  17.98966  -27.24236 0.675 25.67753 ? 287 HOH C O   1 
HETATM 4700 O O   . HOH W  4 .  ? -21.40096 -11.25270 -19.89416 1.000 23.96029 ? 288 HOH C O   1 
HETATM 4701 O O   . HOH W  4 .  ? -20.84156 -7.84997  -17.72044 1.000 18.18524 ? 289 HOH C O   1 
HETATM 4702 O O   . HOH W  4 .  ? 0.25613   -29.74743 -24.52369 1.000 14.53749 ? 290 HOH C O   1 
HETATM 4703 O O   . HOH W  4 .  ? -9.06265  -7.30282  -10.56012 1.000 28.97800 ? 291 HOH C O   1 
HETATM 4704 O O   . HOH W  4 .  ? -15.97490 8.30262   -11.18766 1.000 34.38690 ? 292 HOH C O   1 
HETATM 4705 O O   . HOH W  4 .  ? 9.49931   0.83453   -17.28348 1.000 17.28257 ? 293 HOH C O   1 
HETATM 4706 O O   . HOH W  4 .  ? -15.59832 12.54838  -19.01407 1.000 20.89356 ? 294 HOH C O   1 
HETATM 4707 O O   . HOH W  4 .  ? 3.31448   -12.53655 -19.05089 1.000 29.05527 ? 295 HOH C O   1 
HETATM 4708 O O   . HOH W  4 .  ? 1.44090   -19.76740 -20.21745 1.000 28.41655 ? 296 HOH C O   1 
HETATM 4709 O O   . HOH W  4 .  ? -4.087    2.210     -10.372   1.000 15.22112 ? 297 HOH C O   1 
HETATM 4710 O O   . HOH W  4 .  ? -16.80175 3.48341   -10.96735 1.000 16.52837 ? 298 HOH C O   1 
HETATM 4711 O O   . HOH W  4 .  ? -4.05478  -12.80615 -25.02960 1.000 28.69402 ? 299 HOH C O   1 
HETATM 4712 O O   . HOH W  4 .  ? -18.32438 7.47335   -11.86551 1.000 20.88308 ? 300 HOH C O   1 
HETATM 4713 O O   . HOH W  4 .  ? -14.96884 5.35419   -11.19708 1.000 22.99067 ? 301 HOH C O   1 
HETATM 4714 O O   . HOH W  4 .  ? -9.08781  -0.92110  -8.49740  1.000 29.78155 ? 302 HOH C O   1 
HETATM 4715 O O   . HOH W  4 .  ? 11.94822  3.44246   -25.49921 1.000 13.70747 ? 303 HOH C O   1 
HETATM 4716 O O   . HOH W  4 .  ? -1.53159  13.26440  -20.25489 1.000 25.80853 ? 304 HOH C O   1 
HETATM 4717 O O   . HOH W  4 .  ? 4.16603   -3.44498  -19.38142 1.000 20.97048 ? 305 HOH C O   1 
HETATM 4718 O O   . HOH W  4 .  ? 4.14644   -17.71470 -19.92896 1.000 32.51381 ? 306 HOH C O   1 
HETATM 4719 O O   . HOH W  4 .  ? -8.98099  -1.22966  -29.01414 1.000 10.69000 ? 307 HOH C O   1 
HETATM 4720 O O   . HOH W  4 .  ? 2.70629   -4.20644  -14.89776 1.000 17.96157 ? 308 HOH C O   1 
HETATM 4721 O O   . HOH W  4 .  ? -4.51871  12.96927  -30.94634 0.581 10.25601 ? 309 HOH C O   1 
HETATM 4722 O O   . HOH W  4 .  ? 4.99742   5.12929   -14.91176 0.356 8.94961  ? 310 HOH C O   1 
HETATM 4723 O O   . HOH W  4 .  ? 11.29021  6.06484   -20.60109 1.000 24.05463 ? 311 HOH C O   1 
HETATM 4724 O O   . HOH W  4 .  ? -3.97634  -17.65636 -17.30644 0.581 16.65096 ? 312 HOH C O   1 
HETATM 4725 O O   . HOH W  4 .  ? -0.81763  -18.14989 -17.97199 1.000 34.94157 ? 313 HOH C O   1 
HETATM 4726 O O   . HOH W  4 .  ? -26.45622 -6.36742  -18.95055 1.000 28.70426 ? 314 HOH C O   1 
HETATM 4727 O O   . HOH W  4 .  ? -7.17785  8.98740   -30.92397 1.000 23.12539 ? 315 HOH C O   1 
HETATM 4728 O O   . HOH W  4 .  ? -8.89225  8.80793   -29.27178 1.000 20.80106 ? 316 HOH C O   1 
HETATM 4729 O O   . HOH W  4 .  ? 3.63850   14.50661  -22.60044 1.000 32.02845 ? 317 HOH C O   1 
HETATM 4730 O O   . HOH W  4 .  ? 3.87864   -6.58162  -14.82957 1.000 26.36963 ? 318 HOH C O   1 
HETATM 4731 O O   . HOH W  4 .  ? -6.641    22.345    -22.547   1.000 28.22855 ? 319 HOH C O   1 
HETATM 4732 O O   . HOH W  4 .  ? -1.21786  10.88420  -18.33470 1.000 28.30167 ? 320 HOH C O   1 
HETATM 4733 O O   . HOH W  4 .  ? -1.97641  11.70067  -13.93087 1.000 38.46837 ? 321 HOH C O   1 
HETATM 4734 O O   . HOH W  4 .  ? -12.508   21.606    -20.204   1.000 26.44906 ? 322 HOH C O   1 
HETATM 4735 O O   . HOH W  4 .  ? -11.11970 -11.85246 -14.22386 1.000 29.59555 ? 323 HOH C O   1 
HETATM 4736 O O   . HOH W  4 .  ? 5.56797   -18.14688 -27.81818 1.000 33.94480 ? 324 HOH C O   1 
HETATM 4737 O O   . HOH W  4 .  ? 4.71439   -4.91333  -17.38039 1.000 28.40956 ? 325 HOH C O   1 
HETATM 4738 O O   . HOH W  4 .  ? -6.30780  16.55928  -29.17984 1.000 21.59807 ? 326 HOH C O   1 
HETATM 4739 O O   . HOH W  4 .  ? -0.94201  16.81453  -25.26546 1.000 31.96340 ? 327 HOH C O   1 
HETATM 4740 O O   . HOH W  4 .  ? -13.11111 16.68441  -27.36506 1.000 24.95018 ? 328 HOH C O   1 
HETATM 4741 O O   . HOH W  4 .  ? -7.822    -15.015   -15.569   1.000 18.85000 ? 329 HOH C O   1 
HETATM 4742 O O   . HOH W  4 .  ? -13.59728 -11.80356 -15.16212 1.000 27.12880 ? 330 HOH C O   1 
HETATM 4743 O O   . HOH W  4 .  ? -8.15697  12.46115  -28.02753 1.000 15.25341 ? 331 HOH C O   1 
HETATM 4744 O O   . HOH W  4 .  ? -4.55117  17.43000  -31.02905 1.000 29.96496 ? 332 HOH C O   1 
HETATM 4745 O O   . HOH W  4 .  ? -10.89262 -8.80240  -13.22556 1.000 21.70911 ? 333 HOH C O   1 
HETATM 4746 O O   . HOH W  4 .  ? -9.560    -13.914   -13.671   1.000 19.44117 ? 334 HOH C O   1 
HETATM 4747 O O   . HOH W  4 .  ? -10.51161 16.29707  -27.95958 1.000 25.31385 ? 335 HOH C O   1 
HETATM 4748 O O   . HOH W  4 .  ? 2.01998   -10.15123 -16.73313 1.000 31.89431 ? 336 HOH C O   1 
HETATM 4749 O O   . HOH W  4 .  ? -8.45572  17.84171  -28.10264 1.000 38.81319 ? 337 HOH C O   1 
HETATM 4750 O O   . HOH W  4 .  ? 9.783     -20.188   -24.563   1.000 39.57979 ? 338 HOH C O   1 
HETATM 4751 O O   . HOH W  4 .  ? -9.74577  -11.48123 -10.23247 1.000 35.68213 ? 339 HOH C O   1 
HETATM 4752 O O   . HOH X  4 .  ? 5.19229   -14.83441 -22.20704 1.000 28.50969 ? 201 HOH E O   1 
HETATM 4753 O O   . HOH X  4 .  ? 13.64343  2.27145   -35.85363 1.000 24.93750 ? 202 HOH E O   1 
HETATM 4754 O O   . HOH X  4 .  ? -18.55760 -21.07659 -43.73126 1.000 30.98202 ? 203 HOH E O   1 
HETATM 4755 O O   . HOH X  4 .  ? 7.58338   10.52755  -34.68584 1.000 27.54927 ? 204 HOH E O   1 
HETATM 4756 O O   . HOH X  4 .  ? -6.15703  -25.25374 -46.17411 1.000 15.14050 ? 205 HOH E O   1 
HETATM 4757 O O   . HOH X  4 .  ? -14.51118 17.88288  -44.68971 1.000 34.39889 ? 206 HOH E O   1 
HETATM 4758 O O   . HOH X  4 .  ? 9.15641   -3.22739  -43.42296 1.000 21.86233 ? 207 HOH E O   1 
HETATM 4759 O O   . HOH X  4 .  ? 4.42712   -6.46828  -21.68333 1.000 27.34696 ? 208 HOH E O   1 
HETATM 4760 O O   . HOH X  4 .  ? 2.68075   18.87081  -38.97541 1.000 29.29021 ? 209 HOH E O   1 
HETATM 4761 O O   . HOH X  4 .  ? 8.45467   -9.25518  -25.81809 1.000 22.07575 ? 210 HOH E O   1 
HETATM 4762 O O   . HOH X  4 .  ? -13.04887 14.40808  -37.53771 1.000 22.03249 ? 211 HOH E O   1 
HETATM 4763 O O   . HOH X  4 .  ? -5.32231  19.30257  -37.22434 1.000 22.97419 ? 212 HOH E O   1 
HETATM 4764 O O   . HOH X  4 .  ? -2.67264  -13.30182 -39.24139 1.000 23.66019 ? 213 HOH E O   1 
HETATM 4765 O O   . HOH X  4 .  ? 7.34399   7.89752   -42.34227 1.000 13.58085 ? 214 HOH E O   1 
HETATM 4766 O O   . HOH X  4 .  ? -13.76221 -29.58741 -49.95474 1.000 23.21473 ? 215 HOH E O   1 
HETATM 4767 O O   . HOH X  4 .  ? -0.73298  -6.58247  -31.74570 1.000 8.81945  ? 216 HOH E O   1 
HETATM 4768 O O   . HOH X  4 .  ? -5.69851  -6.86931  -31.29263 0.626 12.41490 ? 217 HOH E O   1 
HETATM 4769 O O   . HOH X  4 .  ? -17.06935 15.77347  -44.40845 1.000 33.26074 ? 218 HOH E O   1 
HETATM 4770 O O   . HOH X  4 .  ? -16.63441 13.95097  -46.79389 0.764 18.53025 ? 219 HOH E O   1 
HETATM 4771 O O   . HOH X  4 .  ? -6.13935  -5.82961  -46.31128 1.000 14.59185 ? 220 HOH E O   1 
HETATM 4772 O O   . HOH X  4 .  ? 4.23232   -9.54562  -35.74878 1.000 14.48907 ? 221 HOH E O   1 
HETATM 4773 O O   . HOH X  4 .  ? -8.525    12.979    -45.760   1.000 12.33858 ? 222 HOH E O   1 
HETATM 4774 O O   . HOH X  4 .  ? -1.24401  -3.61807  -47.82056 1.000 8.28563  ? 223 HOH E O   1 
HETATM 4775 O O   . HOH X  4 .  ? 2.98782   -9.75606  -21.40464 0.617 15.01921 ? 224 HOH E O   1 
HETATM 4776 O O   . HOH X  4 .  ? -3.74453  -9.57277  -44.84724 1.000 16.35474 ? 225 HOH E O   1 
HETATM 4777 O O   . HOH X  4 .  ? 9.33354   -4.59109  -30.12617 1.000 17.09862 ? 226 HOH E O   1 
HETATM 4778 O O   . HOH X  4 .  ? 3.21275   -5.95496  -26.44783 1.000 12.08226 ? 227 HOH E O   1 
HETATM 4779 O O   . HOH X  4 .  ? -6.71945  5.55408   -31.27956 1.000 20.97499 ? 228 HOH E O   1 
HETATM 4780 O O   . HOH X  4 .  ? -7.45280  5.07071   -33.87836 1.000 17.93789 ? 229 HOH E O   1 
HETATM 4781 O O   . HOH X  4 .  ? 8.61655   -12.71302 -25.66300 1.000 34.65420 ? 230 HOH E O   1 
HETATM 4782 O O   . HOH X  4 .  ? -2.32483  -13.77507 -45.92967 1.000 24.92039 ? 231 HOH E O   1 
HETATM 4783 O O   . HOH X  4 .  ? -4.82687  10.19503  -31.22569 1.000 11.56070 ? 232 HOH E O   1 
HETATM 4784 O O   . HOH X  4 .  ? -8.77950  -7.34185  -34.07418 1.000 12.14521 ? 233 HOH E O   1 
HETATM 4785 O O   . HOH X  4 .  ? -6.70064  9.85035   -35.81166 1.000 10.85543 ? 234 HOH E O   1 
HETATM 4786 O O   . HOH X  4 .  ? 1.655     11.410    -42.926   1.000 15.00275 ? 235 HOH E O   1 
HETATM 4787 O O   . HOH X  4 .  ? -10.49304 -6.97763  -44.31312 1.000 12.23439 ? 236 HOH E O   1 
HETATM 4788 O O   . HOH X  4 .  ? -6.14373  -8.44023  -34.16004 1.000 18.26047 ? 237 HOH E O   1 
HETATM 4789 O O   . HOH X  4 .  ? 11.97251  -1.31834  -30.97141 0.690 15.62269 ? 238 HOH E O   1 
HETATM 4790 O O   . HOH X  4 .  ? 6.35167   -8.88798  -33.97681 1.000 13.20043 ? 239 HOH E O   1 
HETATM 4791 O O   . HOH X  4 .  ? -7.64243  -4.28281  -44.55606 1.000 8.10334  ? 240 HOH E O   1 
HETATM 4792 O O   . HOH X  4 .  ? -10.12257 7.29378   -51.45786 1.000 9.10761  ? 241 HOH E O   1 
HETATM 4793 O O   . HOH X  4 .  ? -7.63780  8.67628   -51.91531 1.000 15.56161 ? 242 HOH E O   1 
HETATM 4794 O O   . HOH X  4 .  ? -19.10366 -25.31692 -37.60234 1.000 21.57918 ? 243 HOH E O   1 
HETATM 4795 O O   . HOH X  4 .  ? 12.22872  0.60163   -26.11925 1.000 19.10005 ? 244 HOH E O   1 
HETATM 4796 O O   . HOH X  4 .  ? -12.04673 -30.60612 -45.91232 1.000 24.40699 ? 245 HOH E O   1 
HETATM 4797 O O   . HOH X  4 .  ? 2.87828   -13.66018 -37.97548 1.000 23.41045 ? 246 HOH E O   1 
HETATM 4798 O O   . HOH X  4 .  ? 10.04279  -0.69570  -43.57906 1.000 28.70573 ? 247 HOH E O   1 
HETATM 4799 O O   . HOH X  4 .  ? -10.79881 7.58042   -57.21960 1.000 17.58322 ? 248 HOH E O   1 
HETATM 4800 O O   . HOH X  4 .  ? -15.77737 9.98181   -47.12926 1.000 15.59203 ? 249 HOH E O   1 
HETATM 4801 O O   . HOH X  4 .  ? 4.22557   16.20062  -38.22488 1.000 22.17760 ? 250 HOH E O   1 
HETATM 4802 O O   . HOH X  4 .  ? -2.11296  1.50798   -54.06022 0.603 12.09304 ? 251 HOH E O   1 
HETATM 4803 O O   . HOH X  4 .  ? 4.85899   -2.01342  -43.85791 1.000 14.41548 ? 252 HOH E O   1 
HETATM 4804 O O   . HOH X  4 .  ? 4.98439   -11.20787 -19.75321 1.000 34.92424 ? 253 HOH E O   1 
HETATM 4805 O O   . HOH X  4 .  ? 9.27704   -10.98455 -27.33884 1.000 32.10562 ? 254 HOH E O   1 
HETATM 4806 O O   . HOH X  4 .  ? -9.33626  13.31557  -48.37743 1.000 15.95344 ? 255 HOH E O   1 
HETATM 4807 O O   . HOH X  4 .  ? -14.74779 -24.23634 -53.22671 1.000 19.89185 ? 256 HOH E O   1 
HETATM 4808 O O   . HOH X  4 .  ? 4.62602   -9.22767  -44.44792 1.000 28.77681 ? 257 HOH E O   1 
HETATM 4809 O O   . HOH X  4 .  ? 5.61365   9.45068   -48.67524 1.000 20.06362 ? 258 HOH E O   1 
HETATM 4810 O O   . HOH X  4 .  ? 10.47211  3.03626   -44.80084 1.000 16.80205 ? 259 HOH E O   1 
HETATM 4811 O O   . HOH X  4 .  ? -6.13604  -15.93652 -40.56664 1.000 33.76937 ? 260 HOH E O   1 
HETATM 4812 O O   . HOH X  4 .  ? 4.10748   -14.20725 -41.39756 1.000 31.76667 ? 261 HOH E O   1 
HETATM 4813 O O   . HOH X  4 .  ? -9.05465  -0.15090  -34.22427 1.000 8.57031  ? 262 HOH E O   1 
HETATM 4814 O O   . HOH X  4 .  ? 1.43199   -2.69187  -50.80213 1.000 13.57826 ? 263 HOH E O   1 
HETATM 4815 O O   . HOH X  4 .  ? 8.23785   6.55046   -40.03371 1.000 20.81112 ? 264 HOH E O   1 
HETATM 4816 O O   . HOH X  4 .  ? 9.81030   -7.41517  -36.17739 1.000 19.05069 ? 265 HOH E O   1 
HETATM 4817 O O   . HOH X  4 .  ? 8.84245   -1.98847  -32.22485 1.000 10.71972 ? 266 HOH E O   1 
HETATM 4818 O O   . HOH X  4 .  ? 12.60310  0.29355   -39.96545 1.000 16.03491 ? 267 HOH E O   1 
HETATM 4819 O O   . HOH X  4 .  ? -9.51487  4.92868   -55.04234 1.000 24.10126 ? 268 HOH E O   1 
HETATM 4820 O O   . HOH X  4 .  ? 5.61460   -7.11265  -37.74485 1.000 11.14098 ? 269 HOH E O   1 
HETATM 4821 O O   . HOH X  4 .  ? -7.85728  2.56994   -32.57226 1.000 22.54775 ? 270 HOH E O   1 
HETATM 4822 O O   . HOH X  4 .  ? -5.27819  13.81858  -33.65306 1.000 13.98026 ? 271 HOH E O   1 
HETATM 4823 O O   . HOH X  4 .  ? -11.31271 -2.41761  -54.58627 1.000 18.78028 ? 272 HOH E O   1 
HETATM 4824 O O   . HOH X  4 .  ? -5.86957  -0.93414  -54.72464 0.638 10.06635 ? 273 HOH E O   1 
HETATM 4825 O O   . HOH X  4 .  ? -2.68601  19.49127  -34.33627 1.000 23.39273 ? 274 HOH E O   1 
HETATM 4826 O O   . HOH X  4 .  ? 7.33043   -14.56533 -29.86291 1.000 21.31180 ? 275 HOH E O   1 
HETATM 4827 O O   . HOH X  4 .  ? -8.29695  -10.02066 -31.40295 1.000 20.68789 ? 276 HOH E O   1 
HETATM 4828 O O   . HOH X  4 .  ? 7.13308   -7.49099  -27.58016 0.679 13.60637 ? 277 HOH E O   1 
HETATM 4829 O O   . HOH X  4 .  ? -7.35425  -3.93921  -32.77304 1.000 13.70670 ? 278 HOH E O   1 
HETATM 4830 O O   . HOH X  4 .  ? -5.25894  -5.95987  -50.92985 1.000 34.49743 ? 279 HOH E O   1 
HETATM 4831 O O   . HOH X  4 .  ? -1.29336  13.89780  -43.44555 1.000 15.50709 ? 280 HOH E O   1 
HETATM 4832 O O   . HOH X  4 .  ? 6.80776   1.81599   -46.41476 1.000 11.87306 ? 281 HOH E O   1 
HETATM 4833 O O   . HOH X  4 .  ? -9.97146  13.72535  -43.54775 1.000 12.32433 ? 282 HOH E O   1 
HETATM 4834 O O   . HOH X  4 .  ? -9.01595  13.71637  -36.73129 1.000 12.69310 ? 283 HOH E O   1 
HETATM 4835 O O   . HOH X  4 .  ? -4.30346  -4.56806  -54.38165 1.000 29.15878 ? 284 HOH E O   1 
HETATM 4836 O O   . HOH X  4 .  ? 4.09214   13.49113  -33.09280 1.000 18.18744 ? 285 HOH E O   1 
HETATM 4837 O O   . HOH X  4 .  ? 10.11665  -6.02089  -32.47979 1.000 23.38710 ? 286 HOH E O   1 
HETATM 4838 O O   . HOH X  4 .  ? -8.72120  -1.71959  -54.90975 1.000 22.82492 ? 287 HOH E O   1 
HETATM 4839 O O   . HOH X  4 .  ? -16.51896 11.00492  -50.13035 1.000 36.28096 ? 288 HOH E O   1 
HETATM 4840 O O   . HOH X  4 .  ? -3.12078  -17.94272 -47.30805 1.000 35.14478 ? 289 HOH E O   1 
HETATM 4841 O O   . HOH X  4 .  ? 9.13292   -7.49781  -41.01475 1.000 23.47228 ? 290 HOH E O   1 
HETATM 4842 O O   . HOH X  4 .  ? 9.44511   -6.03885  -27.76342 1.000 18.94916 ? 291 HOH E O   1 
HETATM 4843 O O   . HOH X  4 .  ? -4.84576  -4.90539  -48.45904 0.381 10.87379 ? 292 HOH E O   1 
HETATM 4844 O O   . HOH X  4 .  ? 5.84312   -0.84004  -46.15934 1.000 16.13646 ? 293 HOH E O   1 
HETATM 4845 O O   . HOH X  4 .  ? 2.83306   4.76717   -49.17669 1.000 17.15430 ? 294 HOH E O   1 
HETATM 4846 O O   . HOH X  4 .  ? -6.85693  -1.12625  -32.81197 1.000 8.05053  ? 295 HOH E O   1 
HETATM 4847 O O   . HOH X  4 .  ? 11.86940  -3.76913  -22.86218 1.000 34.65065 ? 296 HOH E O   1 
HETATM 4848 O O   . HOH X  4 .  ? -3.333    -15.391   -38.550   1.000 33.17347 ? 297 HOH E O   1 
HETATM 4849 O O   . HOH X  4 .  ? 10.38394  -4.17598  -20.86658 1.000 32.13827 ? 298 HOH E O   1 
HETATM 4850 O O   . HOH X  4 .  ? -9.69105  16.52428  -42.98818 1.000 22.78871 ? 299 HOH E O   1 
HETATM 4851 O O   . HOH X  4 .  ? -0.79634  -5.76345  -49.44403 1.000 15.32227 ? 300 HOH E O   1 
HETATM 4852 O O   . HOH X  4 .  ? -7.65784  8.78696   -33.53121 1.000 19.86164 ? 301 HOH E O   1 
HETATM 4853 O O   . HOH X  4 .  ? 12.30977  -6.14928  -25.49624 1.000 31.54601 ? 302 HOH E O   1 
HETATM 4854 O O   . HOH X  4 .  ? -22.913   -21.114   -48.580   1.000 29.68647 ? 303 HOH E O   1 
HETATM 4855 O O   . HOH X  4 .  ? -17.84965 9.99287   -44.75048 1.000 27.33818 ? 304 HOH E O   1 
HETATM 4856 O O   . HOH X  4 .  ? -11.02899 -14.04114 -35.16721 1.000 31.98149 ? 305 HOH E O   1 
HETATM 4857 O O   . HOH X  4 .  ? -3.82968  -15.45870 -46.77207 1.000 31.74071 ? 306 HOH E O   1 
HETATM 4858 O O   . HOH X  4 .  ? -5.330    -25.640   -43.184   1.000 22.04426 ? 307 HOH E O   1 
HETATM 4859 O O   . HOH X  4 .  ? -14.58132 13.41470  -51.23073 1.000 36.14704 ? 308 HOH E O   1 
HETATM 4860 O O   . HOH X  4 .  ? -11.34382 12.53885  -36.39993 1.000 25.35671 ? 309 HOH E O   1 
HETATM 4861 O O   . HOH X  4 .  ? -9.95764  -12.32004 -30.83109 1.000 30.98766 ? 310 HOH E O   1 
HETATM 4862 O O   . HOH X  4 .  ? -18.67214 -23.46295 -51.07688 1.000 21.70341 ? 311 HOH E O   1 
HETATM 4863 O O   . HOH X  4 .  ? -9.95778  8.76830   -33.94562 1.000 28.27162 ? 312 HOH E O   1 
HETATM 4864 O O   . HOH X  4 .  ? -3.78340  -13.90337 -32.27791 1.000 30.87799 ? 313 HOH E O   1 
HETATM 4865 O O   . HOH X  4 .  ? -7.26536  16.07520  -41.32572 1.000 27.39990 ? 314 HOH E O   1 
HETATM 4866 O O   . HOH X  4 .  ? -6.71029  19.37953  -39.53804 1.000 29.76524 ? 315 HOH E O   1 
HETATM 4867 O O   . HOH X  4 .  ? -7.90306  11.70713  -52.22960 1.000 20.19437 ? 316 HOH E O   1 
HETATM 4868 O O   . HOH X  4 .  ? -1.696    6.234     -53.221   1.000 14.06489 ? 317 HOH E O   1 
HETATM 4869 O O   . HOH X  4 .  ? -7.56941  13.52939  -50.34609 1.000 19.00275 ? 318 HOH E O   1 
HETATM 4870 O O   . HOH X  4 .  ? -2.30775  -11.23723 -46.57804 1.000 30.73409 ? 319 HOH E O   1 
HETATM 4871 O O   . HOH X  4 .  ? -2.704    -17.411   -34.615   1.000 34.75979 ? 320 HOH E O   1 
HETATM 4872 O O   . HOH X  4 .  ? 10.59062  -9.67875  -34.60064 1.000 30.64997 ? 321 HOH E O   1 
HETATM 4873 O O   . HOH X  4 .  ? -3.31342  -6.88879  -50.14220 1.000 30.14110 ? 322 HOH E O   1 
HETATM 4874 O O   . HOH X  4 .  ? -5.445    10.734    -60.228   1.000 14.83613 ? 323 HOH E O   1 
HETATM 4875 O O   . HOH X  4 .  ? -7.12324  12.47748  -35.12030 1.000 18.08722 ? 324 HOH E O   1 
HETATM 4876 O O   . HOH X  4 .  ? -9.18613  16.47133  -36.64775 1.000 26.30082 ? 325 HOH E O   1 
HETATM 4877 O O   . HOH X  4 .  ? 5.30620   -14.69575 -38.91965 1.000 25.37590 ? 326 HOH E O   1 
HETATM 4878 O O   . HOH X  4 .  ? 8.20209   -10.86997 -34.58053 1.000 18.49737 ? 327 HOH E O   1 
HETATM 4879 O O   . HOH X  4 .  ? 8.14999   -8.39507  -38.16664 1.000 16.79328 ? 328 HOH E O   1 
HETATM 4880 O O   . HOH X  4 .  ? -8.64810  17.72786  -39.44436 1.000 30.34346 ? 329 HOH E O   1 
HETATM 4881 O O   . HOH X  4 .  ? 6.68615   -16.85957 -23.12905 1.000 29.10619 ? 330 HOH E O   1 
HETATM 4882 O O   . HOH X  4 .  ? 11.19150  -2.65497  -42.71639 1.000 35.94598 ? 331 HOH E O   1 
HETATM 4883 O O   . HOH X  4 .  ? -6.29179  16.36790  -33.62406 1.000 22.37949 ? 332 HOH E O   1 
HETATM 4884 O O   . HOH X  4 .  ? 5.27000   -12.01741 -44.29977 1.000 33.99806 ? 333 HOH E O   1 
HETATM 4885 O O   . HOH X  4 .  ? -10.61738 15.60790  -49.57385 1.000 27.14121 ? 334 HOH E O   1 
HETATM 4886 O O   . HOH X  4 .  ? 0.35389   -4.99713  -51.77034 1.000 19.06971 ? 335 HOH E O   1 
HETATM 4887 O O   . HOH X  4 .  ? 7.92850   -10.99954 -37.27564 1.000 26.30914 ? 336 HOH E O   1 
HETATM 4888 O O   . HOH X  4 .  ? 7.48155   -13.33326 -38.45003 1.000 23.24060 ? 337 HOH E O   1 
HETATM 4889 O O   . HOH X  4 .  ? -6.98961  18.02613  -35.58131 1.000 32.74284 ? 338 HOH E O   1 
HETATM 4890 O O   . HOH X  4 .  ? 11.35115  -6.60565  -40.07421 1.000 38.71911 ? 339 HOH E O   1 
HETATM 4891 O O   . HOH X  4 .  ? -13.24162 15.35825  -50.20579 1.000 36.40149 ? 340 HOH E O   1 
HETATM 4892 O O   . HOH X  4 .  ? -8.92144  12.46907  -32.98924 1.000 32.27012 ? 341 HOH E O   1 
HETATM 4893 O O   . HOH X  4 .  ? 8.51038   -13.45635 -40.95294 1.000 37.61396 ? 342 HOH E O   1 
HETATM 4894 O O   . HOH X  4 .  ? 10.05254  -11.60566 -41.43732 1.000 35.59037 ? 343 HOH E O   1 
HETATM 4895 O O   . HOH Y  4 .  ? -28.44672 -11.14173 4.86741   1.000 19.75397 ? 201 HOH F O   1 
HETATM 4896 O O   . HOH Y  4 .  ? -20.24066 -9.54251  16.32011  1.000 30.20842 ? 202 HOH F O   1 
HETATM 4897 O O   . HOH Y  4 .  ? -34.10143 15.64129  -0.15387  1.000 27.55506 ? 203 HOH F O   1 
HETATM 4898 O O   . HOH Y  4 .  ? -13.73924 9.86768   2.95755   1.000 22.86934 ? 204 HOH F O   1 
HETATM 4899 O O   . HOH Y  4 .  ? -27.83253 -4.43332  -15.96527 1.000 24.96912 ? 205 HOH F O   1 
HETATM 4900 O O   . HOH Y  4 .  ? -18.06666 18.90576  -1.44637  1.000 28.34951 ? 206 HOH F O   1 
HETATM 4901 O O   . HOH Y  4 .  ? -18.22106 -6.87575  16.35521  1.000 25.45692 ? 207 HOH F O   1 
HETATM 4902 O O   . HOH Y  4 .  ? -26.04801 19.32706  0.17275   1.000 23.54596 ? 208 HOH F O   1 
HETATM 4903 O O   . HOH Y  4 .  ? -14.17975 7.12043   -4.60110  1.000 13.10580 ? 209 HOH F O   1 
HETATM 4904 O O   . HOH Y  4 .  ? -13.30765 -3.90274  -5.62225  1.000 24.80104 ? 210 HOH F O   1 
HETATM 4905 O O   . HOH Y  4 .  ? -23.47313 -6.39862  6.16712   1.000 8.95139  ? 211 HOH F O   1 
HETATM 4906 O O   . HOH Y  4 .  ? -12.45936 6.46089   -1.27091  1.000 19.27263 ? 212 HOH F O   1 
HETATM 4907 O O   . HOH Y  4 .  ? -23.72197 -3.43495  -9.92720  1.000 8.85184  ? 213 HOH F O   1 
HETATM 4908 O O   . HOH Y  4 .  ? -28.81029 -5.27917  -8.44291  1.000 15.70587 ? 214 HOH F O   1 
HETATM 4909 O O   . HOH Y  4 .  ? -31.90647 8.03397   -13.75750 1.000 10.36611 ? 215 HOH F O   1 
HETATM 4910 O O   . HOH Y  4 .  ? -11.09249 3.56682   1.42337   1.000 19.78193 ? 216 HOH F O   1 
HETATM 4911 O O   . HOH Y  4 .  ? -9.225    -1.844    5.052     0.441 11.11025 ? 217 HOH F O   1 
HETATM 4912 O O   . HOH Y  4 .  ? -18.73436 -9.94434  2.20630   1.000 14.34403 ? 218 HOH F O   1 
HETATM 4913 O O   . HOH Y  4 .  ? -28.27618 6.59532   6.25296   1.000 19.22040 ? 219 HOH F O   1 
HETATM 4914 O O   . HOH Y  4 .  ? -18.60041 12.19003  -4.53816  1.000 29.54057 ? 220 HOH F O   1 
HETATM 4915 O O   . HOH Y  4 .  ? -13.23669 -5.60371  7.93094   1.000 16.18881 ? 221 HOH F O   1 
HETATM 4916 O O   . HOH Y  4 .  ? -18.62818 -9.60757  -6.44299  1.000 27.37997 ? 222 HOH F O   1 
HETATM 4917 O O   . HOH Y  4 .  ? -11.48313 1.84283   -6.90414  1.000 24.67494 ? 223 HOH F O   1 
HETATM 4918 O O   . HOH Y  4 .  ? -30.15124 -3.63791  -6.66878  1.000 8.76502  ? 224 HOH F O   1 
HETATM 4919 O O   . HOH Y  4 .  ? -26.08033 10.75312  6.42762   1.000 11.80334 ? 225 HOH F O   1 
HETATM 4920 O O   . HOH Y  4 .  ? -25.26109 0.80881   -16.45614 0.649 9.47437  ? 226 HOH F O   1 
HETATM 4921 O O   . HOH Y  4 .  ? -19.49544 -6.06192  11.49382  1.000 13.10021 ? 227 HOH F O   1 
HETATM 4922 O O   . HOH Y  4 .  ? -37.60607 15.27538  -9.38581  1.000 28.85562 ? 228 HOH F O   1 
HETATM 4923 O O   . HOH Y  4 .  ? -22.51627 13.80759  -5.89899  1.000 21.71520 ? 229 HOH F O   1 
HETATM 4924 O O   . HOH Y  4 .  ? -16.63465 15.85762  -0.46122  1.000 19.07864 ? 230 HOH F O   1 
HETATM 4925 O O   . HOH Y  4 .  ? -27.95241 10.48078  1.78124   1.000 10.82855 ? 231 HOH F O   1 
HETATM 4926 O O   . HOH Y  4 .  ? -16.66007 -9.36958  3.96900   1.000 11.18010 ? 232 HOH F O   1 
HETATM 4927 O O   . HOH Y  4 .  ? -25.68211 -13.82067 -7.79136  1.000 22.02460 ? 233 HOH F O   1 
HETATM 4928 O O   . HOH Y  4 .  ? -29.36724 13.70828  -7.91312  1.000 17.13266 ? 234 HOH F O   1 
HETATM 4929 O O   . HOH Y  4 .  ? -8.20117  0.88839   0.81953   1.000 16.20840 ? 235 HOH F O   1 
HETATM 4930 O O   . HOH Y  4 .  ? -27.37372 9.36384   -14.46052 1.000 16.80927 ? 236 HOH F O   1 
HETATM 4931 O O   . HOH Y  4 .  ? -29.36538 5.74827   3.83433   1.000 14.86625 ? 237 HOH F O   1 
HETATM 4932 O O   . HOH Y  4 .  ? -15.81883 -4.77057  -8.13081  1.000 26.54582 ? 238 HOH F O   1 
HETATM 4933 O O   . HOH Y  4 .  ? -26.81304 -9.19594  -6.83368  1.000 16.24405 ? 239 HOH F O   1 
HETATM 4934 O O   . HOH Y  4 .  ? -11.10022 -1.06689  -4.78760  1.000 32.85524 ? 240 HOH F O   1 
HETATM 4935 O O   . HOH Y  4 .  ? -12.77500 -7.08122  5.38800   1.000 25.37678 ? 241 HOH F O   1 
HETATM 4936 O O   . HOH Y  4 .  ? -37.19048 11.18762  -9.36071  1.000 13.56244 ? 242 HOH F O   1 
HETATM 4937 O O   . HOH Y  4 .  ? -9.73973  5.59626   6.82311   1.000 10.73408 ? 243 HOH F O   1 
HETATM 4938 O O   . HOH Y  4 .  ? -13.53828 -1.14955  -6.76128  1.000 29.98221 ? 244 HOH F O   1 
HETATM 4939 O O   . HOH Y  4 .  ? -17.55419 -2.45879  -5.99634  1.000 13.68967 ? 245 HOH F O   1 
HETATM 4940 O O   . HOH Y  4 .  ? -20.52607 8.88038   -11.24716 1.000 25.40824 ? 246 HOH F O   1 
HETATM 4941 O O   . HOH Y  4 .  ? -13.12825 -8.23846  1.83618   1.000 18.78696 ? 247 HOH F O   1 
HETATM 4942 O O   . HOH Y  4 .  ? -21.45398 -2.80693  -13.10663 1.000 15.33753 ? 248 HOH F O   1 
HETATM 4943 O O   . HOH Y  4 .  ? -21.36769 -15.68368 -4.67277  0.490 12.85758 ? 249 HOH F O   1 
HETATM 4944 O O   . HOH Y  4 .  ? -37.74526 17.57296  -6.63255  1.000 26.43722 ? 250 HOH F O   1 
HETATM 4945 O O   . HOH Y  4 .  ? -28.45695 -12.69986 0.42454   1.000 23.07315 ? 251 HOH F O   1 
HETATM 4946 O O   . HOH Y  4 .  ? -10.85151 -0.14745  11.92111  1.000 9.83674  ? 252 HOH F O   1 
HETATM 4947 O O   . HOH Y  4 .  ? -15.93671 -14.79317 8.51077   1.000 29.71149 ? 253 HOH F O   1 
HETATM 4948 O O   . HOH Y  4 .  ? -24.79455 9.67942   -10.71031 1.000 21.42041 ? 254 HOH F O   1 
HETATM 4949 O O   . HOH Y  4 .  ? -33.21581 -5.75041  3.96030   0.460 10.46265 ? 255 HOH F O   1 
HETATM 4950 O O   . HOH Y  4 .  ? -19.33023 4.50306   -11.68857 1.000 13.26618 ? 256 HOH F O   1 
HETATM 4951 O O   . HOH Y  4 .  ? -9.48719  -0.25532  -2.14240  1.000 21.39353 ? 257 HOH F O   1 
HETATM 4952 O O   . HOH Y  4 .  ? -15.85593 -8.12679  10.41302  1.000 15.34597 ? 258 HOH F O   1 
HETATM 4953 O O   . HOH Y  4 .  ? -21.69250 7.38766   -13.76178 1.000 25.22379 ? 259 HOH F O   1 
HETATM 4954 O O   . HOH Y  4 .  ? -26.71199 -14.40712 -0.49265  1.000 20.28216 ? 260 HOH F O   1 
HETATM 4955 O O   . HOH Y  4 .  ? -30.96305 0.14402   -17.44588 0.661 20.25055 ? 261 HOH F O   1 
HETATM 4956 O O   . HOH Y  4 .  ? -29.86496 3.09945   4.85204   1.000 18.63890 ? 262 HOH F O   1 
HETATM 4957 O O   . HOH Y  4 .  ? -38.06703 11.87867  -11.93247 1.000 26.08342 ? 263 HOH F O   1 
HETATM 4958 O O   . HOH Y  4 .  ? -13.44178 -2.74810  5.72611   1.000 10.59494 ? 264 HOH F O   1 
HETATM 4959 O O   . HOH Y  4 .  ? -20.35566 -13.85328 -0.18950  1.000 15.48752 ? 265 HOH F O   1 
HETATM 4960 O O   . HOH Y  4 .  ? -20.14488 10.64755  -7.29379  1.000 26.91997 ? 266 HOH F O   1 
HETATM 4961 O O   . HOH Y  4 .  ? -17.16429 -7.50457  0.23318   1.000 10.74921 ? 267 HOH F O   1 
HETATM 4962 O O   . HOH Y  4 .  ? -30.06872 14.48092  0.86343   1.000 12.09862 ? 268 HOH F O   1 
HETATM 4963 O O   . HOH Y  4 .  ? -11.19011 -7.45154  -1.74359  1.000 33.76652 ? 269 HOH F O   1 
HETATM 4964 O O   . HOH Y  4 .  ? -38.27454 9.71371   -15.12537 1.000 28.17341 ? 270 HOH F O   1 
HETATM 4965 O O   . HOH Y  4 .  ? -31.26668 0.57856   3.62484   1.000 9.62923  ? 271 HOH F O   1 
HETATM 4966 O O   . HOH Y  4 .  ? -30.91145 14.53212  -5.81572  1.000 14.04155 ? 272 HOH F O   1 
HETATM 4967 O O   . HOH Y  4 .  ? -14.88261 -10.13284 12.36104  1.000 25.85874 ? 273 HOH F O   1 
HETATM 4968 O O   . HOH Y  4 .  ? -9.38193  -2.34387  7.77755   1.000 14.94677 ? 274 HOH F O   1 
HETATM 4969 O O   . HOH Y  4 .  ? -23.54232 19.15513  3.02403   1.000 22.16045 ? 275 HOH F O   1 
HETATM 4970 O O   . HOH Y  4 .  ? -13.40144 -6.83556  10.41012  1.000 16.19214 ? 276 HOH F O   1 
HETATM 4971 O O   . HOH Y  4 .  ? -16.92737 13.31379  4.53098   1.000 16.28695 ? 277 HOH F O   1 
HETATM 4972 O O   . HOH Y  4 .  ? -31.94046 -2.93909  4.52673   1.000 17.17555 ? 278 HOH F O   1 
HETATM 4973 O O   . HOH Y  4 .  ? -30.66854 17.29461  -5.13832  1.000 25.78349 ? 279 HOH F O   1 
HETATM 4974 O O   . HOH Y  4 .  ? -16.52740 -1.42451  -8.33446  1.000 17.58592 ? 280 HOH F O   1 
HETATM 4975 O O   . HOH Y  4 .  ? -29.90936 -15.13798 -2.35636  1.000 27.02864 ? 281 HOH F O   1 
HETATM 4976 O O   . HOH Y  4 .  ? -31.44930 -2.37485  -17.03042 1.000 32.96865 ? 282 HOH F O   1 
HETATM 4977 O O   . HOH Y  4 .  ? -31.75396 -9.05232  6.49289   1.000 21.22963 ? 283 HOH F O   1 
HETATM 4978 O O   . HOH Y  4 .  ? -33.65014 -1.62635  -16.81722 1.000 23.86339 ? 284 HOH F O   1 
HETATM 4979 O O   . HOH Y  4 .  ? -24.94609 12.88796  -7.12877  1.000 24.88434 ? 285 HOH F O   1 
HETATM 4980 O O   . HOH Y  4 .  ? -26.40482 14.32130  3.85899   1.000 13.94462 ? 286 HOH F O   1 
HETATM 4981 O O   . HOH Y  4 .  ? -27.99213 -0.48730  -17.00468 0.603 11.87699 ? 287 HOH F O   1 
HETATM 4982 O O   . HOH Y  4 .  ? -30.04022 13.91195  -10.78691 1.000 23.07760 ? 288 HOH F O   1 
HETATM 4983 O O   . HOH Y  4 .  ? -32.64408 13.62376  0.66922   1.000 12.90567 ? 289 HOH F O   1 
HETATM 4984 O O   . HOH Y  4 .  ? -34.53558 18.77736  -7.77551  1.000 31.61261 ? 290 HOH F O   1 
HETATM 4985 O O   . HOH Y  4 .  ? -24.53544 8.17683   -14.45720 1.000 22.22550 ? 291 HOH F O   1 
HETATM 4986 O O   . HOH Y  4 .  ? -13.77340 -8.18977  -2.79871  1.000 23.40180 ? 292 HOH F O   1 
HETATM 4987 O O   . HOH Y  4 .  ? -27.71329 -15.27704 -8.68942  1.000 29.62569 ? 293 HOH F O   1 
HETATM 4988 O O   . HOH Y  4 .  ? -10.43532 7.44146   0.69342   1.000 22.52277 ? 294 HOH F O   1 
HETATM 4989 O O   . HOH Y  4 .  ? -29.56510 -3.07479  5.69936   1.000 14.08752 ? 295 HOH F O   1 
HETATM 4990 O O   . HOH Y  4 .  ? -29.08159 -0.40775  5.05613   1.000 8.07035  ? 296 HOH F O   1 
HETATM 4991 O O   . HOH Y  4 .  ? -11.62281 -4.73882  15.49942  1.000 30.52692 ? 297 HOH F O   1 
HETATM 4992 O O   . HOH Y  4 .  ? -32.155   5.183     -18.257   1.000 31.00813 ? 298 HOH F O   1 
HETATM 4993 O O   . HOH Y  4 .  ? -9.533    8.966     4.472     1.000 29.44767 ? 299 HOH F O   1 
HETATM 4994 O O   . HOH Y  4 .  ? -11.46275 -4.52211  17.92523  1.000 33.25682 ? 300 HOH F O   1 
HETATM 4995 O O   . HOH Y  4 .  ? -22.96427 -5.36504  -11.76295 1.000 21.60985 ? 301 HOH F O   1 
HETATM 4996 O O   . HOH Y  4 .  ? -31.42900 9.86468   3.32553   1.000 19.57084 ? 302 HOH F O   1 
HETATM 4997 O O   . HOH Y  4 .  ? -29.10980 9.60974   4.04097   1.000 18.02345 ? 303 HOH F O   1 
HETATM 4998 O O   . HOH Y  4 .  ? -10.63744 -4.79187  7.15420   1.000 24.45845 ? 304 HOH F O   1 
HETATM 4999 O O   . HOH Y  4 .  ? -20.11643 13.13828  -6.25885  1.000 35.58586 ? 305 HOH F O   1 
HETATM 5000 O O   . HOH Y  4 .  ? -15.38464 -14.16054 4.29868   1.000 29.83168 ? 306 HOH F O   1 
HETATM 5001 O O   . HOH Y  4 .  ? -28.52414 9.64746   6.38267   1.000 23.02687 ? 307 HOH F O   1 
HETATM 5002 O O   . HOH Y  4 .  ? -29.657   -19.360   -8.852    1.000 25.02064 ? 308 HOH F O   1 
HETATM 5003 O O   . HOH Y  4 .  ? -39.30792 11.37031  -7.25807  1.000 20.21873 ? 309 HOH F O   1 
HETATM 5004 O O   . HOH Y  4 .  ? -17.77871 -17.26277 5.60443   1.000 29.32988 ? 310 HOH F O   1 
HETATM 5005 O O   . HOH Y  4 .  ? -27.71691 -16.47793 0.01050   1.000 35.71533 ? 311 HOH F O   1 
HETATM 5006 O O   . HOH Y  4 .  ? -29.99921 17.35428  0.38663   1.000 21.01741 ? 312 HOH F O   1 
HETATM 5007 O O   . HOH Y  4 .  ? -9.093    5.532     1.922     1.000 14.56780 ? 313 HOH F O   1 
HETATM 5008 O O   . HOH Y  4 .  ? -25.49750 -11.08280 -8.68780  1.000 29.11776 ? 314 HOH F O   1 
HETATM 5009 O O   . HOH Y  4 .  ? -14.95146 -11.43541 3.44623   1.000 16.99949 ? 315 HOH F O   1 
HETATM 5010 O O   . HOH Y  4 .  ? -14.76990 -8.95790  -0.16301  1.000 15.34203 ? 316 HOH F O   1 
HETATM 5011 O O   . HOH Y  4 .  ? -12.43570 -10.65032 3.45653   1.000 25.38215 ? 317 HOH F O   1 
HETATM 5012 O O   . HOH Y  4 .  ? -28.35900 13.07153  2.47079   1.000 16.57246 ? 318 HOH F O   1 
HETATM 5013 O O   . HOH Y  4 .  ? -25.27093 17.61297  6.23453   1.000 32.56727 ? 319 HOH F O   1 
HETATM 5014 O O   . HOH Y  4 .  ? -30.37424 11.86295  -16.06307 1.000 28.44850 ? 320 HOH F O   1 
HETATM 5015 O O   . HOH Y  4 .  ? -18.14350 -14.90195 -1.18181  1.000 19.71198 ? 321 HOH F O   1 
HETATM 5016 O O   . HOH Y  4 .  ? -31.04502 16.14039  -12.15860 1.000 35.28865 ? 322 HOH F O   1 
HETATM 5017 O O   . HOH Y  4 .  ? -28.51938 18.89379  -1.47574  1.000 26.59622 ? 323 HOH F O   1 
HETATM 5018 O O   . HOH Y  4 .  ? -15.53724 15.87017  -3.03346  1.000 37.01116 ? 324 HOH F O   1 
HETATM 5019 O O   . HOH Y  4 .  ? -27.17409 16.88192  4.08338   1.000 21.47091 ? 325 HOH F O   1 
HETATM 5020 O O   . HOH Y  4 .  ? -35.94967 17.77566  -9.63462  1.000 32.63888 ? 326 HOH F O   1 
HETATM 5021 O O   . HOH Y  4 .  ? -32.252   21.337    -1.621    1.000 34.24963 ? 327 HOH F O   1 
HETATM 5022 O O   . HOH Y  4 .  ? -40.57420 14.66937  -9.35782  1.000 30.92084 ? 328 HOH F O   1 
HETATM 5023 O O   . HOH Y  4 .  ? -15.82953 -13.74540 -0.34280  0.656 14.83869 ? 329 HOH F O   1 
HETATM 5024 O O   . HOH Y  4 .  ? -14.85244 -11.50375 0.64237   1.000 23.36496 ? 330 HOH F O   1 
HETATM 5025 O O   . HOH Y  4 .  ? -14.88817 -12.23261 -5.17812  1.000 34.87955 ? 331 HOH F O   1 
HETATM 5026 O O   . HOH Y  4 .  ? -28.06702 18.32812  2.06202   1.000 29.63625 ? 332 HOH F O   1 
HETATM 5027 O O   . HOH Y  4 .  ? -14.69881 -15.32774 1.77736   1.000 25.34781 ? 333 HOH F O   1 
HETATM 5028 O O   . HOH Y  4 .  ? -15.06911 -14.23397 -2.91699  1.000 34.47827 ? 334 HOH F O   1 
HETATM 5029 O O   . HOH Z  4 .  ? -30.59773 7.83127   28.84688  1.000 26.31667 ? 201 HOH D O   1 
HETATM 5030 O O   . HOH Z  4 .  ? -41.01128 -12.65360 21.26273  1.000 34.79861 ? 202 HOH D O   1 
HETATM 5031 O O   . HOH Z  4 .  ? -35.09889 -5.50438  13.44071  1.000 10.12253 ? 203 HOH D O   1 
HETATM 5032 O O   . HOH Z  4 .  ? -28.10211 19.78018  13.61448  1.000 31.37394 ? 204 HOH D O   1 
HETATM 5033 O O   . HOH Z  4 .  ? -44.775   1.781     24.114    0.351 9.33430  ? 205 HOH D O   1 
HETATM 5034 O O   . HOH Z  4 .  ? -45.93634 -8.67487  11.48930  1.000 22.92197 ? 206 HOH D O   1 
HETATM 5035 O O   . HOH Z  4 .  ? -27.72474 -17.63989 19.04472  1.000 31.63760 ? 207 HOH D O   1 
HETATM 5036 O O   . HOH Z  4 .  ? -9.680    3.329     16.899    1.000 24.75462 ? 208 HOH D O   1 
HETATM 5037 O O   . HOH Z  4 .  ? -30.20844 -16.02655 18.20664  1.000 32.61517 ? 209 HOH D O   1 
HETATM 5038 O O   . HOH Z  4 .  ? -31.33869 -5.14330  27.55110  1.000 31.51554 ? 210 HOH D O   1 
HETATM 5039 O O   . HOH Z  4 .  ? -33.73181 -16.10696 18.23334  1.000 30.70799 ? 211 HOH D O   1 
HETATM 5040 O O   . HOH Z  4 .  ? -46.67776 -5.59265  13.06424  1.000 24.91241 ? 212 HOH D O   1 
HETATM 5041 O O   . HOH Z  4 .  ? -23.89691 15.37420  5.62968   1.000 17.12278 ? 213 HOH D O   1 
HETATM 5042 O O   . HOH Z  4 .  ? -21.09509 -2.35553  21.20728  1.000 8.87851  ? 214 HOH D O   1 
HETATM 5043 O O   . HOH Z  4 .  ? -31.87945 17.97644  18.59617  1.000 27.36290 ? 215 HOH D O   1 
HETATM 5044 O O   . HOH Z  4 .  ? -21.16276 10.22526  22.69862  1.000 20.77354 ? 216 HOH D O   1 
HETATM 5045 O O   . HOH Z  4 .  ? -41.64209 -3.57100  21.25590  1.000 11.35585 ? 217 HOH D O   1 
HETATM 5046 O O   . HOH Z  4 .  ? -29.97830 9.32214   25.53931  1.000 18.81017 ? 218 HOH D O   1 
HETATM 5047 O O   . HOH Z  4 .  ? -38.60910 -4.94931  26.84365  1.000 25.97162 ? 219 HOH D O   1 
HETATM 5048 O O   . HOH Z  4 .  ? -24.170   18.517    20.134    1.000 34.40105 ? 220 HOH D O   1 
HETATM 5049 O O   . HOH Z  4 .  ? -28.07658 13.77376  21.35586  0.634 18.06948 ? 221 HOH D O   1 
HETATM 5050 O O   . HOH Z  4 .  ? -34.33387 -8.40302  19.86161  1.000 14.13117 ? 222 HOH D O   1 
HETATM 5051 O O   . HOH Z  4 .  ? -19.94086 -4.70204  16.32176  1.000 12.45133 ? 223 HOH D O   1 
HETATM 5052 O O   . HOH Z  4 .  ? -32.64423 6.50850   7.97633   1.000 20.07433 ? 224 HOH D O   1 
HETATM 5053 O O   . HOH Z  4 .  ? -37.80183 10.74761  25.38336  1.000 21.03637 ? 225 HOH D O   1 
HETATM 5054 O O   . HOH Z  4 .  ? -33.61346 11.19105  9.58970   1.000 13.59870 ? 226 HOH D O   1 
HETATM 5055 O O   . HOH Z  4 .  ? -20.66678 -3.30219  14.03732  1.000 8.14437  ? 227 HOH D O   1 
HETATM 5056 O O   . HOH Z  4 .  ? -13.23434 8.30133   15.05247  1.000 9.49108  ? 228 HOH D O   1 
HETATM 5057 O O   . HOH Z  4 .  ? -15.04435 10.23098  19.20149  1.000 21.85947 ? 229 HOH D O   1 
HETATM 5058 O O   . HOH Z  4 .  ? -19.38715 14.08322  13.75198  1.000 16.84377 ? 230 HOH D O   1 
HETATM 5059 O O   . HOH Z  4 .  ? -28.58737 10.89640  10.30403  1.000 10.26813 ? 231 HOH D O   1 
HETATM 5060 O O   . HOH Z  4 .  ? -29.88925 6.08915   8.57072   1.000 16.99188 ? 232 HOH D O   1 
HETATM 5061 O O   . HOH Z  4 .  ? -39.10315 3.43305   27.89873  1.000 13.48166 ? 233 HOH D O   1 
HETATM 5062 O O   . HOH Z  4 .  ? -36.98713 -6.32543  24.68160  1.000 16.08373 ? 234 HOH D O   1 
HETATM 5063 O O   . HOH Z  4 .  ? -14.59150 1.30722   22.89117  1.000 11.89295 ? 235 HOH D O   1 
HETATM 5064 O O   . HOH Z  4 .  ? -14.25814 10.78279  7.88425   1.000 12.98529 ? 236 HOH D O   1 
HETATM 5065 O O   . HOH Z  4 .  ? -41.76745 7.75530   24.02272  1.000 11.84141 ? 237 HOH D O   1 
HETATM 5066 O O   . HOH Z  4 .  ? -13.747   -4.040    20.438    1.000 27.82754 ? 238 HOH D O   1 
HETATM 5067 O O   . HOH Z  4 .  ? -36.88746 -7.70671  20.73665  1.000 11.79943 ? 239 HOH D O   1 
HETATM 5068 O O   . HOH Z  4 .  ? -31.74595 -12.49196 20.34284  1.000 21.87953 ? 240 HOH D O   1 
HETATM 5069 O O   . HOH Z  4 .  ? -48.81446 -2.71241  19.90789  0.534 11.00286 ? 241 HOH D O   1 
HETATM 5070 O O   . HOH Z  4 .  ? -28.26471 -14.00178 15.49031  1.000 20.63527 ? 242 HOH D O   1 
HETATM 5071 O O   . HOH Z  4 .  ? -10.89421 0.44073   18.27296  0.590 13.44937 ? 243 HOH D O   1 
HETATM 5072 O O   . HOH Z  4 .  ? -27.47958 -10.49946 25.34300  1.000 30.22028 ? 244 HOH D O   1 
HETATM 5073 O O   . HOH Z  4 .  ? -48.94001 -3.91829  14.96839  1.000 26.29614 ? 245 HOH D O   1 
HETATM 5074 O O   . HOH Z  4 .  ? -11.64619 11.73023  8.75005   1.000 26.05982 ? 246 HOH D O   1 
HETATM 5075 O O   . HOH Z  4 .  ? -22.47457 -8.55851  17.67470  1.000 14.65680 ? 247 HOH D O   1 
HETATM 5076 O O   . HOH Z  4 .  ? -27.86608 -12.32688 13.22407  0.562 13.32302 ? 248 HOH D O   1 
HETATM 5077 O O   . HOH Z  4 .  ? -32.41887 7.72551   25.22403  1.000 23.31084 ? 249 HOH D O   1 
HETATM 5078 O O   . HOH Z  4 .  ? -16.93075 18.44736  9.05100   1.000 28.40250 ? 250 HOH D O   1 
HETATM 5079 O O   . HOH Z  4 .  ? -31.07188 3.58909   7.63589   1.000 22.90842 ? 251 HOH D O   1 
HETATM 5080 O O   . HOH Z  4 .  ? -22.72098 -7.56376  23.81886  1.000 24.93487 ? 252 HOH D O   1 
HETATM 5081 O O   . HOH Z  4 .  ? -35.05703 1.62660   29.01604  1.000 13.92454 ? 253 HOH D O   1 
HETATM 5082 O O   . HOH Z  4 .  ? -38.37166 -12.18808 21.39309  1.000 20.53344 ? 254 HOH D O   1 
HETATM 5083 O O   . HOH Z  4 .  ? -9.78361  5.91933   17.22640  1.000 20.83548 ? 255 HOH D O   1 
HETATM 5084 O O   . HOH Z  4 .  ? -39.56697 -0.78685  21.96116  1.000 8.36400  ? 256 HOH D O   1 
HETATM 5085 O O   . HOH Z  4 .  ? -32.81120 -5.61346  8.82962   1.000 21.08237 ? 257 HOH D O   1 
HETATM 5086 O O   . HOH Z  4 .  ? -33.33124 -5.84702  22.12021  1.000 11.10991 ? 258 HOH D O   1 
HETATM 5087 O O   . HOH Z  4 .  ? -19.70511 -4.41245  22.44649  1.000 14.03727 ? 259 HOH D O   1 
HETATM 5088 O O   . HOH Z  4 .  ? -7.55363  8.78105   16.88511  1.000 16.85921 ? 260 HOH D O   1 
HETATM 5089 O O   . HOH Z  4 .  ? -42.70155 -6.34209  17.97592  1.000 13.01568 ? 261 HOH D O   1 
HETATM 5090 O O   . HOH Z  4 .  ? -44.06464 -10.70830 19.41531  1.000 30.06045 ? 262 HOH D O   1 
HETATM 5091 O O   . HOH Z  4 .  ? -29.79380 -0.12618  27.67442  1.000 30.71437 ? 263 HOH D O   1 
HETATM 5092 O O   . HOH Z  4 .  ? -28.83766 0.77969   7.49281   1.000 8.12419  ? 264 HOH D O   1 
HETATM 5093 O O   . HOH Z  4 .  ? -18.63419 11.16669  21.84975  1.000 27.03733 ? 265 HOH D O   1 
HETATM 5094 O O   . HOH Z  4 .  ? -22.10308 -12.53454 19.55483  1.000 30.14449 ? 266 HOH D O   1 
HETATM 5095 O O   . HOH Z  4 .  ? -28.59162 -12.56604 23.21337  1.000 31.39730 ? 267 HOH D O   1 
HETATM 5096 O O   . HOH Z  4 .  ? -42.35057 -0.18303  24.00709  1.000 13.73348 ? 268 HOH D O   1 
HETATM 5097 O O   . HOH Z  4 .  ? -22.10901 13.80520  16.92377  1.000 23.38416 ? 269 HOH D O   1 
HETATM 5098 O O   . HOH Z  4 .  ? -31.17642 14.88753  10.29223  1.000 19.30775 ? 270 HOH D O   1 
HETATM 5099 O O   . HOH Z  4 .  ? -27.12062 -0.70349  24.88725  1.000 14.83232 ? 271 HOH D O   1 
HETATM 5100 O O   . HOH Z  4 .  ? -21.73245 6.19416   25.13667  1.000 19.17878 ? 272 HOH D O   1 
HETATM 5101 O O   . HOH Z  4 .  ? -20.24173 14.68447  11.24945  1.000 12.44424 ? 273 HOH D O   1 
HETATM 5102 O O   . HOH Z  4 .  ? -44.89629 -8.37028  18.15374  1.000 19.95696 ? 274 HOH D O   1 
HETATM 5103 O O   . HOH Z  4 .  ? -10.99024 -1.80447  17.75446  1.000 29.11571 ? 275 HOH D O   1 
HETATM 5104 O O   . HOH Z  4 .  ? -17.76828 4.14593   23.12313  1.000 12.66416 ? 276 HOH D O   1 
HETATM 5105 O O   . HOH Z  4 .  ? -43.77351 -4.99199  20.14670  1.000 12.29309 ? 277 HOH D O   1 
HETATM 5106 O O   . HOH Z  4 .  ? -12.91688 9.42172   17.50889  1.000 14.86381 ? 278 HOH D O   1 
HETATM 5107 O O   . HOH Z  4 .  ? -35.97754 15.25959  17.89541  1.000 30.07941 ? 279 HOH D O   1 
HETATM 5108 O O   . HOH Z  4 .  ? -37.47690 6.22540   25.54962  1.000 25.38904 ? 280 HOH D O   1 
HETATM 5109 O O   . HOH Z  4 .  ? -18.59405 -3.61336  18.44464  1.000 16.80334 ? 281 HOH D O   1 
HETATM 5110 O O   . HOH Z  4 .  ? -30.84342 -2.93329  8.25996   1.000 15.05311 ? 282 HOH D O   1 
HETATM 5111 O O   . HOH Z  4 .  ? -25.09646 -7.36517  22.59942  1.000 18.29357 ? 283 HOH D O   1 
HETATM 5112 O O   . HOH Z  4 .  ? -40.09288 -4.78019  23.26926  1.000 14.74882 ? 284 HOH D O   1 
HETATM 5113 O O   . HOH Z  4 .  ? -24.47346 14.80381  18.40698  0.666 22.02806 ? 285 HOH D O   1 
HETATM 5114 O O   . HOH Z  4 .  ? -27.38962 -6.49769  26.73537  1.000 29.85185 ? 286 HOH D O   1 
HETATM 5115 O O   . HOH Z  4 .  ? -26.65104 14.63162  8.75475   1.000 11.85515 ? 287 HOH D O   1 
HETATM 5116 O O   . HOH Z  4 .  ? -26.48632 3.05403   27.57740  1.000 17.80813 ? 288 HOH D O   1 
HETATM 5117 O O   . HOH Z  4 .  ? -20.66949 17.55763  10.89682  0.775 20.98593 ? 289 HOH D O   1 
HETATM 5118 O O   . HOH Z  4 .  ? -12.65062 0.18326   20.62631  1.000 12.02047 ? 290 HOH D O   1 
HETATM 5119 O O   . HOH Z  4 .  ? -16.24068 9.36830   21.25110  1.000 33.76289 ? 291 HOH D O   1 
HETATM 5120 O O   . HOH Z  4 .  ? -24.56237 12.22177  21.43632  1.000 29.21883 ? 292 HOH D O   1 
HETATM 5121 O O   . HOH Z  4 .  ? -19.34008 10.73899  19.29683  1.000 26.44361 ? 293 HOH D O   1 
HETATM 5122 O O   . HOH Z  4 .  ? -31.17099 -0.09989  8.66802   1.000 8.57168  ? 294 HOH D O   1 
HETATM 5123 O O   . HOH Z  4 .  ? -30.96094 17.52140  9.47110   1.000 33.38970 ? 295 HOH D O   1 
HETATM 5124 O O   . HOH Z  4 .  ? -9.85451  -0.96751  15.21166  1.000 32.23565 ? 296 HOH D O   1 
HETATM 5125 O O   . HOH Z  4 .  ? -31.03142 17.48894  21.15825  1.000 32.57580 ? 297 HOH D O   1 
HETATM 5126 O O   . HOH Z  4 .  ? -30.18821 9.90208   8.32144   1.000 17.46273 ? 298 HOH D O   1 
HETATM 5127 O O   . HOH Z  4 .  ? -18.62063 -7.64378  19.04550  1.000 29.91005 ? 299 HOH D O   1 
HETATM 5128 O O   . HOH Z  4 .  ? -18.83622 8.01591   24.52490  0.627 18.98635 ? 300 HOH D O   1 
HETATM 5129 O O   . HOH Z  4 .  ? -31.57581 -6.31676  6.40261   1.000 14.01046 ? 301 HOH D O   1 
HETATM 5130 O O   . HOH Z  4 .  ? -27.01782 -8.15664  24.43498  1.000 22.33097 ? 302 HOH D O   1 
HETATM 5131 O O   . HOH Z  4 .  ? -26.04490 -15.44297 13.61994  1.000 23.45700 ? 303 HOH D O   1 
HETATM 5132 O O   . HOH Z  4 .  ? -48.88590 -8.89922  11.40566  1.000 34.69672 ? 304 HOH D O   1 
HETATM 5133 O O   . HOH Z  4 .  ? -50.11395 -3.07844  17.47944  1.000 26.31889 ? 305 HOH D O   1 
HETATM 5134 O O   . HOH Z  4 .  ? -29.70134 5.47565   29.84253  1.000 25.98382 ? 306 HOH D O   1 
HETATM 5135 O O   . HOH Z  4 .  ? -16.74073 14.37786  14.84278  1.000 27.53639 ? 307 HOH D O   1 
HETATM 5136 O O   . HOH Z  4 .  ? -28.98230 13.54011  9.88986   1.000 17.21204 ? 308 HOH D O   1 
HETATM 5137 O O   . HOH Z  4 .  ? -27.36645 6.56348   31.25107  1.000 28.78990 ? 309 HOH D O   1 
HETATM 5138 O O   . HOH Z  4 .  ? -15.15521 10.95862  4.94795   1.000 29.57529 ? 310 HOH D O   1 
HETATM 5139 O O   . HOH Z  4 .  ? -40.074   7.231     26.182    1.000 17.12587 ? 311 HOH D O   1 
HETATM 5140 O O   . HOH Z  4 .  ? -24.258   6.872     28.776    1.000 28.83095 ? 312 HOH D O   1 
HETATM 5141 O O   . HOH Z  4 .  ? -45.48724 -5.86958  22.07442  1.000 26.45840 ? 313 HOH D O   1 
HETATM 5142 O O   . HOH Z  4 .  ? -21.95558 11.28597  19.41395  1.000 32.72830 ? 314 HOH D O   1 
HETATM 5143 O O   . HOH Z  4 .  ? -23.06802 -9.16299  25.89612  1.000 31.03358 ? 315 HOH D O   1 
HETATM 5144 O O   . HOH Z  4 .  ? -32.86805 -6.90782  26.86832  1.000 32.31234 ? 316 HOH D O   1 
HETATM 5145 O O   . HOH Z  4 .  ? -18.39424 19.08149  11.64558  1.000 31.55265 ? 317 HOH D O   1 
HETATM 5146 O O   . HOH Z  4 .  ? -17.77842 13.62468  17.68931  1.000 34.40939 ? 318 HOH D O   1 
HETATM 5147 O O   . HOH Z  4 .  ? -34.42935 -7.13536  24.42494  1.000 18.28002 ? 319 HOH D O   1 
HETATM 5148 O O   . HOH Z  4 .  ? -18.06653 -5.58036  20.74485  1.000 24.01128 ? 320 HOH D O   1 
HETATM 5149 O O   . HOH Z  4 .  ? -21.18786 -9.94633  19.85307  1.000 25.63702 ? 321 HOH D O   1 
HETATM 5150 O O   . HOH Z  4 .  ? -33.56739 18.04840  9.85166   1.000 35.59391 ? 322 HOH D O   1 
HETATM 5151 O O   . HOH Z  4 .  ? -38.50848 -8.62215  24.79749  1.000 22.01298 ? 323 HOH D O   1 
HETATM 5152 O O   . HOH Z  4 .  ? -26.78784 17.30823  8.52052   0.845 22.81224 ? 324 HOH D O   1 
HETATM 5153 O O   . HOH Z  4 .  ? -34.64429 -9.96991  23.75523  1.000 25.90153 ? 325 HOH D O   1 
HETATM 5154 O O   . HOH Z  4 .  ? -37.30026 -9.73736  22.56290  1.000 16.35425 ? 326 HOH D O   1 
HETATM 5155 O O   . HOH Z  4 .  ? -21.68811 11.51263  24.80929  1.000 37.43194 ? 327 HOH D O   1 
HETATM 5156 O O   . HOH Z  4 .  ? -31.75138 -1.43421  29.32702  1.000 32.37785 ? 328 HOH D O   1 
HETATM 5157 O O   . HOH Z  4 .  ? -26.61912 13.28105  6.40272   1.000 22.94422 ? 329 HOH D O   1 
HETATM 5158 O O   . HOH Z  4 .  ? -34.41417 -0.95443  29.45631  1.000 22.82889 ? 330 HOH D O   1 
HETATM 5159 O O   . HOH Z  4 .  ? -20.91513 -9.15628  22.38020  1.000 30.73238 ? 331 HOH D O   1 
HETATM 5160 O O   . HOH AA 4 .  ? -42.28024 23.82453  2.87972   1.000 25.91816 ? 201 HOH A O   1 
HETATM 5161 O O   . HOH AA 4 .  ? -32.52035 -5.03060  -15.52426 1.000 29.94026 ? 202 HOH A O   1 
HETATM 5162 O O   . HOH AA 4 .  ? -44.91210 8.94798   -7.57156  1.000 28.35119 ? 203 HOH A O   1 
HETATM 5163 O O   . HOH AA 4 .  ? -53.52644 7.17670   -4.99871  1.000 36.50064 ? 204 HOH A O   1 
HETATM 5164 O O   . HOH AA 4 .  ? -36.00833 -5.96059  -0.33484  1.000 8.98416  ? 205 HOH A O   1 
HETATM 5165 O O   . HOH AA 4 .  ? -34.06823 15.70994  11.02524  1.000 26.01478 ? 206 HOH A O   1 
HETATM 5166 O O   . HOH AA 4 .  ? -37.51944 -11.43934 -10.82146 1.000 33.28437 ? 207 HOH A O   1 
HETATM 5167 O O   . HOH AA 4 .  ? -48.60100 8.95433   -3.16295  1.000 15.93390 ? 208 HOH A O   1 
HETATM 5168 O O   . HOH AA 4 .  ? -40.36252 20.51843  14.89412  1.000 24.49188 ? 209 HOH A O   1 
HETATM 5169 O O   . HOH AA 4 .  ? -50.16396 11.32468  12.96310  1.000 18.72961 ? 210 HOH A O   1 
HETATM 5170 O O   . HOH AA 4 .  ? -37.34533 20.18255  4.16729   1.000 33.74002 ? 211 HOH A O   1 
HETATM 5171 O O   . HOH AA 4 .  ? -49.39665 -1.70953  7.84656   1.000 8.53774  ? 212 HOH A O   1 
HETATM 5172 O O   . HOH AA 4 .  ? -43.38223 14.95860  10.90906  0.735 13.63769 ? 213 HOH A O   1 
HETATM 5173 O O   . HOH AA 4 .  ? -49.74748 3.78789   20.36860  1.000 12.61414 ? 214 HOH A O   1 
HETATM 5174 O O   . HOH AA 4 .  ? -36.62889 -13.00437 8.46145   1.000 31.06959 ? 215 HOH A O   1 
HETATM 5175 O O   . HOH AA 4 .  ? -50.821   10.711    5.792     1.000 30.71007 ? 216 HOH A O   1 
HETATM 5176 O O   . HOH AA 4 .  ? -47.54919 9.87233   16.39249  1.000 7.62580  ? 217 HOH A O   1 
HETATM 5177 O O   . HOH AA 4 .  ? -33.32107 -6.05117  -6.29539  1.000 12.77691 ? 218 HOH A O   1 
HETATM 5178 O O   . HOH AA 4 .  ? -41.68936 -5.02384  14.18871  1.000 11.11557 ? 219 HOH A O   1 
HETATM 5179 O O   . HOH AA 4 .  ? -42.14434 -8.87827  -2.49197  1.000 14.76082 ? 220 HOH A O   1 
HETATM 5180 O O   . HOH AA 4 .  ? -52.647   -2.631    14.230    1.000 31.00496 ? 221 HOH A O   1 
HETATM 5181 O O   . HOH AA 4 .  ? -40.80737 10.29307  -11.36225 1.000 23.35159 ? 222 HOH A O   1 
HETATM 5182 O O   . HOH AA 4 .  ? -32.82900 10.94221  1.33349   1.000 10.20619 ? 223 HOH A O   1 
HETATM 5183 O O   . HOH AA 4 .  ? -41.67062 -8.48555  -5.25529  1.000 11.92764 ? 224 HOH A O   1 
HETATM 5184 O O   . HOH AA 4 .  ? -41.66697 -16.65232 -0.29482  1.000 30.62524 ? 225 HOH A O   1 
HETATM 5185 O O   . HOH AA 4 .  ? -33.84612 6.33887   5.35734   1.000 20.60612 ? 226 HOH A O   1 
HETATM 5186 O O   . HOH AA 4 .  ? -47.09512 7.59055   -5.20028  1.000 19.66755 ? 227 HOH A O   1 
HETATM 5187 O O   . HOH AA 4 .  ? -45.69325 -3.81866  11.49026  1.000 13.37003 ? 228 HOH A O   1 
HETATM 5188 O O   . HOH AA 4 .  ? -39.71382 -5.09197  -10.13091 1.000 21.01316 ? 229 HOH A O   1 
HETATM 5189 O O   . HOH AA 4 .  ? -35.71940 10.99847  5.25186   1.000 9.38339  ? 230 HOH A O   1 
HETATM 5190 O O   . HOH AA 4 .  ? -49.79424 -7.83324  1.64976   0.624 20.83553 ? 231 HOH A O   1 
HETATM 5191 O O   . HOH AA 4 .  ? -41.90568 10.79397  -7.74026  1.000 22.57949 ? 232 HOH A O   1 
HETATM 5192 O O   . HOH AA 4 .  ? -43.31525 -2.37892  11.73118  1.000 8.17175  ? 233 HOH A O   1 
HETATM 5193 O O   . HOH AA 4 .  ? -32.87119 -21.03945 16.28997  1.000 29.28875 ? 234 HOH A O   1 
HETATM 5194 O O   . HOH AA 4 .  ? -47.48229 -12.77222 1.05471   1.000 25.81469 ? 235 HOH A O   1 
HETATM 5195 O O   . HOH AA 4 .  ? -42.69996 20.22756  -2.17057  1.000 27.02458 ? 236 HOH A O   1 
HETATM 5196 O O   . HOH AA 4 .  ? -53.42369 8.55848   7.47630   1.000 19.85398 ? 237 HOH A O   1 
HETATM 5197 O O   . HOH AA 4 .  ? -51.73661 0.16823   17.39317  0.696 16.74897 ? 238 HOH A O   1 
HETATM 5198 O O   . HOH AA 4 .  ? -51.57315 -6.48793  0.28562   1.000 37.32647 ? 239 HOH A O   1 
HETATM 5199 O O   . HOH AA 4 .  ? -43.15853 16.94881  -3.41045  1.000 21.09716 ? 240 HOH A O   1 
HETATM 5200 O O   . HOH AA 4 .  ? -36.35568 -0.23933  -14.03916 1.000 9.89951  ? 241 HOH A O   1 
HETATM 5201 O O   . HOH AA 4 .  ? -32.48050 4.62288   3.80102   1.000 23.67134 ? 242 HOH A O   1 
HETATM 5202 O O   . HOH AA 4 .  ? -47.51238 -11.99000 8.69965   1.000 29.20535 ? 243 HOH A O   1 
HETATM 5203 O O   . HOH AA 4 .  ? -45.706   14.021    0.029     1.000 22.50214 ? 244 HOH A O   1 
HETATM 5204 O O   . HOH AA 4 .  ? -39.17602 21.55988  10.77141  1.000 32.43098 ? 245 HOH A O   1 
HETATM 5205 O O   . HOH AA 4 .  ? -43.28628 14.74423  20.24807  1.000 15.65801 ? 246 HOH A O   1 
HETATM 5206 O O   . HOH AA 4 .  ? -45.39311 4.71774   -10.68053 0.568 12.37475 ? 247 HOH A O   1 
HETATM 5207 O O   . HOH AA 4 .  ? -39.31329 -12.34960 8.10883   1.000 33.33133 ? 248 HOH A O   1 
HETATM 5208 O O   . HOH AA 4 .  ? -44.55293 -6.30052  -2.96385  1.000 13.54487 ? 249 HOH A O   1 
HETATM 5209 O O   . HOH AA 4 .  ? -34.66829 18.16602  0.79197   1.000 27.26523 ? 250 HOH A O   1 
HETATM 5210 O O   . HOH AA 4 .  ? -45.74278 -7.94833  8.86563   1.000 14.10156 ? 251 HOH A O   1 
HETATM 5211 O O   . HOH AA 4 .  ? -36.19621 -7.73771  -9.01353  1.000 20.46805 ? 252 HOH A O   1 
HETATM 5212 O O   . HOH AA 4 .  ? -54.03814 2.40291   12.34445  1.000 10.43747 ? 253 HOH A O   1 
HETATM 5213 O O   . HOH AA 4 .  ? -50.26594 8.02457   22.21214  1.000 16.69634 ? 254 HOH A O   1 
HETATM 5214 O O   . HOH AA 4 .  ? -40.69734 12.48813  18.52284  1.000 11.12963 ? 255 HOH A O   1 
HETATM 5215 O O   . HOH AA 4 .  ? -43.93223 -12.73662 -0.21843  0.638 15.28430 ? 256 HOH A O   1 
HETATM 5216 O O   . HOH AA 4 .  ? -52.61957 4.98233   9.20442   1.000 13.32037 ? 257 HOH A O   1 
HETATM 5217 O O   . HOH AA 4 .  ? -33.32344 -8.86325  -7.35494  1.000 24.36290 ? 258 HOH A O   1 
HETATM 5218 O O   . HOH AA 4 .  ? -40.90498 -2.01067  -8.84654  1.000 9.28679  ? 259 HOH A O   1 
HETATM 5219 O O   . HOH AA 4 .  ? -33.24555 -2.81040  6.87777   1.000 18.94172 ? 260 HOH A O   1 
HETATM 5220 O O   . HOH AA 4 .  ? -49.79474 -0.78474  0.68742   1.000 17.88176 ? 261 HOH A O   1 
HETATM 5221 O O   . HOH AA 4 .  ? -36.25994 20.62252  -0.13417  1.000 27.28219 ? 262 HOH A O   1 
HETATM 5222 O O   . HOH AA 4 .  ? -43.96742 8.56387   -11.83997 1.000 17.74349 ? 263 HOH A O   1 
HETATM 5223 O O   . HOH AA 4 .  ? -35.22567 14.95014  7.36058   1.000 10.43462 ? 264 HOH A O   1 
HETATM 5224 O O   . HOH AA 4 .  ? -42.48540 -6.24368  -9.44617  1.000 28.92319 ? 265 HOH A O   1 
HETATM 5225 O O   . HOH AA 4 .  ? -42.26697 -16.56924 3.41675   1.000 31.59311 ? 266 HOH A O   1 
HETATM 5226 O O   . HOH AA 4 .  ? -46.35819 6.56809   -9.05412  1.000 21.08763 ? 267 HOH A O   1 
HETATM 5227 O O   . HOH AA 4 .  ? -40.83907 6.09716   -13.07407 1.000 12.24892 ? 268 HOH A O   1 
HETATM 5228 O O   . HOH AA 4 .  ? -49.60389 0.52694   -8.03410  1.000 23.35903 ? 269 HOH A O   1 
HETATM 5229 O O   . HOH AA 4 .  ? -52.19527 3.40515   -0.22056  1.000 16.58938 ? 270 HOH A O   1 
HETATM 5230 O O   . HOH AA 4 .  ? -45.26689 -7.17351  -7.06996  1.000 25.83496 ? 271 HOH A O   1 
HETATM 5231 O O   . HOH AA 4 .  ? -33.49434 0.91392   7.50853   1.000 9.13582  ? 272 HOH A O   1 
HETATM 5232 O O   . HOH AA 4 .  ? -31.09610 7.34235   2.59320   1.000 17.55903 ? 273 HOH A O   1 
HETATM 5233 O O   . HOH AA 4 .  ? -32.93462 3.38603   5.61319   0.700 21.42604 ? 274 HOH A O   1 
HETATM 5234 O O   . HOH AA 4 .  ? -52.46457 6.56745   4.48736   1.000 12.46725 ? 275 HOH A O   1 
HETATM 5235 O O   . HOH AA 4 .  ? -50.10712 1.12256   19.47814  1.000 14.29403 ? 276 HOH A O   1 
HETATM 5236 O O   . HOH AA 4 .  ? -36.83884 -6.80553  -11.26799 1.000 27.38864 ? 277 HOH A O   1 
HETATM 5237 O O   . HOH AA 4 .  ? -38.72617 13.70022  -5.78756  1.000 17.11847 ? 278 HOH A O   1 
HETATM 5238 O O   . HOH AA 4 .  ? -34.48082 14.73724  2.55265   1.000 11.86646 ? 279 HOH A O   1 
HETATM 5239 O O   . HOH AA 4 .  ? -40.80859 15.66019  11.30575  1.000 12.48209 ? 280 HOH A O   1 
HETATM 5240 O O   . HOH AA 4 .  ? -43.62033 21.27802  0.30715   1.000 20.39205 ? 281 HOH A O   1 
HETATM 5241 O O   . HOH AA 4 .  ? -52.93124 1.67378   15.11512  1.000 14.15568 ? 282 HOH A O   1 
HETATM 5242 O O   . HOH AA 4 .  ? -47.14585 4.16833   21.18850  1.000 11.22691 ? 283 HOH A O   1 
HETATM 5243 O O   . HOH AA 4 .  ? -48.18672 -2.65154  11.39834  0.437 11.06627 ? 284 HOH A O   1 
HETATM 5244 O O   . HOH AA 4 .  ? -47.410   12.481    3.136     1.000 29.62912 ? 285 HOH A O   1 
HETATM 5245 O O   . HOH AA 4 .  ? -35.23654 -9.84308  -10.90128 1.000 32.49943 ? 286 HOH A O   1 
HETATM 5246 O O   . HOH AA 4 .  ? -40.98132 -2.77677  -12.36898 1.000 23.21279 ? 287 HOH A O   1 
HETATM 5247 O O   . HOH AA 4 .  ? -35.35170 -10.85607 4.68561   1.000 18.64102 ? 288 HOH A O   1 
HETATM 5248 O O   . HOH AA 4 .  ? -50.97496 6.52316   18.25402  1.000 16.49414 ? 289 HOH A O   1 
HETATM 5249 O O   . HOH AA 4 .  ? -40.98477 -13.60206 5.63558   1.000 31.38088 ? 290 HOH A O   1 
HETATM 5250 O O   . HOH AA 4 .  ? -52.80356 -3.33742  -1.49000  1.000 28.54087 ? 291 HOH A O   1 
HETATM 5251 O O   . HOH AA 4 .  ? -47.99453 -14.43431 2.91257   1.000 36.43235 ? 292 HOH A O   1 
HETATM 5252 O O   . HOH AA 4 .  ? -52.72800 -8.76333  4.38742   1.000 30.45700 ? 293 HOH A O   1 
HETATM 5253 O O   . HOH AA 4 .  ? -40.91964 -14.86365 8.64936   1.000 32.34764 ? 294 HOH A O   1 
HETATM 5254 O O   . HOH AA 4 .  ? -34.19799 -11.98236 7.15979   1.000 31.25764 ? 295 HOH A O   1 
HETATM 5255 O O   . HOH AA 4 .  ? -48.62414 -6.50903  11.56362  1.000 30.27553 ? 296 HOH A O   1 
HETATM 5256 O O   . HOH AA 4 .  ? -33.52406 -0.19903  4.96520   1.000 10.81116 ? 297 HOH A O   1 
HETATM 5257 O O   . HOH AA 4 .  ? -40.63424 18.23329  10.26173  1.000 19.89685 ? 298 HOH A O   1 
HETATM 5258 O O   . HOH AA 4 .  ? -51.10992 -4.02725  13.43865  1.000 33.05994 ? 299 HOH A O   1 
HETATM 5259 O O   . HOH AA 4 .  ? -24.75102 -6.82312  -12.86888 1.000 31.38389 ? 300 HOH A O   1 
HETATM 5260 O O   . HOH AA 4 .  ? -33.36662 9.70756   5.07848   1.000 16.81372 ? 301 HOH A O   1 
HETATM 5261 O O   . HOH AA 4 .  ? -45.276   14.193    6.963     1.000 27.53211 ? 302 HOH A O   1 
HETATM 5262 O O   . HOH AA 4 .  ? -48.331   11.872    8.623     1.000 29.31047 ? 303 HOH A O   1 
HETATM 5263 O O   . HOH AA 4 .  ? -51.21296 -3.68561  8.53741   1.000 12.69499 ? 304 HOH A O   1 
HETATM 5264 O O   . HOH AA 4 .  ? -45.71956 15.85217  -2.71852  1.000 30.18380 ? 305 HOH A O   1 
HETATM 5265 O O   . HOH AA 4 .  ? -32.62885 9.67129   7.55893   1.000 23.56624 ? 306 HOH A O   1 
HETATM 5266 O O   . HOH AA 4 .  ? -55.705   7.608     -3.469    1.000 21.25338 ? 307 HOH A O   1 
HETATM 5267 O O   . HOH AA 4 .  ? -46.815   11.975    6.527     1.000 30.63071 ? 308 HOH A O   1 
HETATM 5268 O O   . HOH AA 4 .  ? -38.791   23.665    12.178    1.000 31.52288 ? 309 HOH A O   1 
HETATM 5269 O O   . HOH AA 4 .  ? -41.034   -18.383   1.763     1.000 33.47358 ? 310 HOH A O   1 
HETATM 5270 O O   . HOH AA 4 .  ? -42.51538 16.78596  -6.07382  0.739 30.32113 ? 311 HOH A O   1 
HETATM 5271 O O   . HOH AA 4 .  ? -55.33322 -9.37033  5.91562   1.000 32.15683 ? 312 HOH A O   1 
HETATM 5272 O O   . HOH AA 4 .  ? -51.524   5.848     20.794    1.000 16.07939 ? 313 HOH A O   1 
HETATM 5273 O O   . HOH AA 4 .  ? -34.92576 17.74454  7.34918   1.000 20.23658 ? 314 HOH A O   1 
HETATM 5274 O O   . HOH AA 4 .  ? -48.01820 -9.44540  8.94476   1.000 38.12152 ? 315 HOH A O   1 
HETATM 5275 O O   . HOH AA 4 .  ? -47.046   14.638    2.937     1.000 26.10704 ? 316 HOH A O   1 
HETATM 5276 O O   . HOH AA 4 .  ? -42.690   26.159    4.608     1.000 23.70566 ? 317 HOH A O   1 
HETATM 5277 O O   . HOH AA 4 .  ? -50.49263 -4.59646  11.01473  1.000 21.68801 ? 318 HOH A O   1 
HETATM 5278 O O   . HOH AA 4 .  ? -51.619   11.564    7.780     1.000 26.55962 ? 319 HOH A O   1 
HETATM 5279 O O   . HOH AA 4 .  ? -41.265   -16.191   -5.851    1.000 25.57348 ? 320 HOH A O   1 
HETATM 5280 O O   . HOH AA 4 .  ? -46.11539 -7.86276  -4.75699  1.000 21.09516 ? 321 HOH A O   1 
HETATM 5281 O O   . HOH AA 4 .  ? -40.51225 17.73813  7.71908   1.000 32.92597 ? 322 HOH A O   1 
HETATM 5282 O O   . HOH AA 4 .  ? -33.37560 13.75061  8.88408   1.000 19.52912 ? 323 HOH A O   1 
HETATM 5283 O O   . HOH AA 4 .  ? -43.13093 -10.56958 -6.38323  1.000 18.00984 ? 324 HOH A O   1 
HETATM 5284 O O   . HOH AA 4 .  ? -34.78316 13.60615  5.04829   1.000 14.84803 ? 325 HOH A O   1 
HETATM 5285 O O   . HOH AA 4 .  ? -44.27315 -9.85721  -8.39055  1.000 31.30968 ? 326 HOH A O   1 
HETATM 5286 O O   . HOH AA 4 .  ? -39.41619 24.27236  2.91124   1.000 33.49640 ? 327 HOH A O   1 
HETATM 5287 O O   . HOH AA 4 .  ? -52.85680 -2.46210  17.25449  1.000 29.94769 ? 328 HOH A O   1 
HETATM 5288 O O   . HOH AA 4 .  ? -33.80085 17.33754  3.15464   1.000 21.03597 ? 329 HOH A O   1 
HETATM 5289 O O   . HOH AA 4 .  ? -43.04657 19.60620  10.75617  1.000 34.84752 ? 330 HOH A O   1 
HETATM 5290 O O   . HOH AA 4 .  ? -46.33932 19.14014  7.55676   1.000 34.91230 ? 331 HOH A O   1 
HETATM 5291 O O   . HOH AA 4 .  ? -35.02737 18.98745  4.97509   1.000 24.88868 ? 332 HOH A O   1 
HETATM 5292 O O   . HOH AA 4 .  ? -35.827   23.621    11.297    1.000 26.49172 ? 333 HOH A O   1 
# 
