data_9GN7
# 
_entry.id   9GN7 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GN7         pdb_00009gn7 10.2210/pdb9gn7/pdb 
WWPDB D_1292141049 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2024-11-13 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.country'                 
2 2 'Structure model' '_citation.journal_abbrev'          
3 2 'Structure model' '_citation.journal_id_ISSN'         
4 2 'Structure model' '_citation.journal_volume'          
5 2 'Structure model' '_citation.page_first'              
6 2 'Structure model' '_citation.page_last'               
7 2 'Structure model' '_citation.pdbx_database_id_DOI'    
8 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
9 2 'Structure model' '_citation.title'                   
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GN7 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 5 
_pdbx_contact_author.email              michael.lammers@uni-greifswald.de 
_pdbx_contact_author.name_first         Michael 
_pdbx_contact_author.name_last          Lammers 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4168-4640 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Qin, C.'     1 0009-0004-8907-4264 
'Graf, L.G.'  2 0009-0007-7269-1743 
'Schulze, S.' 3 0000-0002-0122-5688 
'Palm, G.J.'  4 0000-0003-0329-0413 
'Lammers, M.' 5 0000-0003-4168-4640 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                9496 
_citation.page_last                 9496 
_citation.title                     'Distribution and diversity of classical deacylases in bacteria.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-53903-0 
_citation.pdbx_database_id_PubMed   39489725 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Graf, L.G.'        1  0009-0007-7269-1743 
primary 'Moreno-Yruela, C.' 2  0000-0003-2450-6519 
primary 'Qin, C.'           3  ?                   
primary 'Schulze, S.'       4  0000-0002-0122-5688 
primary 'Palm, G.J.'        5  0000-0003-0329-0413 
primary 'Schmoker, O.'      6  ?                   
primary 'Wang, N.'          7  0000-0001-7623-1858 
primary 'Hocking, D.M.'     8  0000-0002-3485-0586 
primary 'Jebeli, L.'        9  0000-0003-4240-9528 
primary 'Girbardt, B.'      10 ?                   
primary 'Berndt, L.'        11 ?                   
primary 'Dorre, B.'         12 ?                   
primary 'Weis, D.M.'        13 ?                   
primary 'Janetzky, M.'      14 ?                   
primary 'Albrecht, D.'      15 ?                   
primary 'Zuhlke, D.'        16 ?                   
primary 'Sievers, S.'       17 0000-0002-5457-2552 
primary 'Strugnell, R.A.'   18 0000-0003-0614-5641 
primary 'Olsen, C.A.'       19 0000-0002-2953-8942 
primary 'Hofmann, K.'       20 0000-0002-2289-9083 
primary 'Lammers, M.'       21 0000-0003-4168-4640 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Deacetylase      41617.188 1   3.5.1.- ? ? 'His6-tgged fusion-protein' 
2 non-polymer syn 'POTASSIUM ION'  39.098    2   ?       ? ? ?                           
3 non-polymer syn 'ZINC ION'       65.409    1   ?       ? ? ?                           
4 non-polymer syn 'PHOSPHATE ION'  94.971    1   ?       ? ? ?                           
5 non-polymer syn 'TRICHOSTATIN A' 302.368   1   ?       ? ? ?                           
6 non-polymer syn GLYCEROL         92.094    2   ?       ? ? ?                           
7 water       nat water            18.015    119 ?       ? ? ?                           
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAHHHHHHVGTMKRKTGFFFDERCFWHSTGLHAVTLPVGGWVQPPAGGGHAESPETKRRMKNLMDVSGLTPQLALRSAAP
ASLEDLRRIHPDSYLERFKAISDNGGGMLGKEAPLGPGSYEIACLSAGLACAAVEAVLKGELDNAYSLSRPPGHHCLPDQ
SMGFCFLANIPIAVERAKAQLGLGKVAIIDWDVHHGNGTQHIYLQRDDVLTISLHQDGCFPPGYAGEDDRGVGAGEGYNI
NIPLLAGAGDDSWRYALETIVIPALARFEPELIIIACGYDANAMDPLARMQLHSDSFRAMTEQVQQAADRLCGGKLVMVH
EGGYAESYVPFCGLAVMEALSGIRTEVQDPLLEFIQQQQPRATFAQFQRQAIDRLAQQFGLQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAHHHHHHVGTMKRKTGFFFDERCFWHSTGLHAVTLPVGGWVQPPAGGGHAESPETKRRMKNLMDVSGLTPQLALRSAAP
ASLEDLRRIHPDSYLERFKAISDNGGGMLGKEAPLGPGSYEIACLSAGLACAAVEAVLKGELDNAYSLSRPPGHHCLPDQ
SMGFCFLANIPIAVERAKAQLGLGKVAIIDWDVHHGNGTQHIYLQRDDVLTISLHQDGCFPPGYAGEDDRGVGAGEGYNI
NIPLLAGAGDDSWRYALETIVIPALARFEPELIIIACGYDANAMDPLARMQLHSDSFRAMTEQVQQAADRLCGGKLVMVH
EGGYAESYVPFCGLAVMEALSGIRTEVQDPLLEFIQQQQPRATFAQFQRQAIDRLAQQFGLQ
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'POTASSIUM ION'  K   
3 'ZINC ION'       ZN  
4 'PHOSPHATE ION'  PO4 
5 'TRICHOSTATIN A' TSN 
6 GLYCEROL         GOL 
7 water            HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   HIS n 
1 4   HIS n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   VAL n 
1 10  GLY n 
1 11  THR n 
1 12  MET n 
1 13  LYS n 
1 14  ARG n 
1 15  LYS n 
1 16  THR n 
1 17  GLY n 
1 18  PHE n 
1 19  PHE n 
1 20  PHE n 
1 21  ASP n 
1 22  GLU n 
1 23  ARG n 
1 24  CYS n 
1 25  PHE n 
1 26  TRP n 
1 27  HIS n 
1 28  SER n 
1 29  THR n 
1 30  GLY n 
1 31  LEU n 
1 32  HIS n 
1 33  ALA n 
1 34  VAL n 
1 35  THR n 
1 36  LEU n 
1 37  PRO n 
1 38  VAL n 
1 39  GLY n 
1 40  GLY n 
1 41  TRP n 
1 42  VAL n 
1 43  GLN n 
1 44  PRO n 
1 45  PRO n 
1 46  ALA n 
1 47  GLY n 
1 48  GLY n 
1 49  GLY n 
1 50  HIS n 
1 51  ALA n 
1 52  GLU n 
1 53  SER n 
1 54  PRO n 
1 55  GLU n 
1 56  THR n 
1 57  LYS n 
1 58  ARG n 
1 59  ARG n 
1 60  MET n 
1 61  LYS n 
1 62  ASN n 
1 63  LEU n 
1 64  MET n 
1 65  ASP n 
1 66  VAL n 
1 67  SER n 
1 68  GLY n 
1 69  LEU n 
1 70  THR n 
1 71  PRO n 
1 72  GLN n 
1 73  LEU n 
1 74  ALA n 
1 75  LEU n 
1 76  ARG n 
1 77  SER n 
1 78  ALA n 
1 79  ALA n 
1 80  PRO n 
1 81  ALA n 
1 82  SER n 
1 83  LEU n 
1 84  GLU n 
1 85  ASP n 
1 86  LEU n 
1 87  ARG n 
1 88  ARG n 
1 89  ILE n 
1 90  HIS n 
1 91  PRO n 
1 92  ASP n 
1 93  SER n 
1 94  TYR n 
1 95  LEU n 
1 96  GLU n 
1 97  ARG n 
1 98  PHE n 
1 99  LYS n 
1 100 ALA n 
1 101 ILE n 
1 102 SER n 
1 103 ASP n 
1 104 ASN n 
1 105 GLY n 
1 106 GLY n 
1 107 GLY n 
1 108 MET n 
1 109 LEU n 
1 110 GLY n 
1 111 LYS n 
1 112 GLU n 
1 113 ALA n 
1 114 PRO n 
1 115 LEU n 
1 116 GLY n 
1 117 PRO n 
1 118 GLY n 
1 119 SER n 
1 120 TYR n 
1 121 GLU n 
1 122 ILE n 
1 123 ALA n 
1 124 CYS n 
1 125 LEU n 
1 126 SER n 
1 127 ALA n 
1 128 GLY n 
1 129 LEU n 
1 130 ALA n 
1 131 CYS n 
1 132 ALA n 
1 133 ALA n 
1 134 VAL n 
1 135 GLU n 
1 136 ALA n 
1 137 VAL n 
1 138 LEU n 
1 139 LYS n 
1 140 GLY n 
1 141 GLU n 
1 142 LEU n 
1 143 ASP n 
1 144 ASN n 
1 145 ALA n 
1 146 TYR n 
1 147 SER n 
1 148 LEU n 
1 149 SER n 
1 150 ARG n 
1 151 PRO n 
1 152 PRO n 
1 153 GLY n 
1 154 HIS n 
1 155 HIS n 
1 156 CYS n 
1 157 LEU n 
1 158 PRO n 
1 159 ASP n 
1 160 GLN n 
1 161 SER n 
1 162 MET n 
1 163 GLY n 
1 164 PHE n 
1 165 CYS n 
1 166 PHE n 
1 167 LEU n 
1 168 ALA n 
1 169 ASN n 
1 170 ILE n 
1 171 PRO n 
1 172 ILE n 
1 173 ALA n 
1 174 VAL n 
1 175 GLU n 
1 176 ARG n 
1 177 ALA n 
1 178 LYS n 
1 179 ALA n 
1 180 GLN n 
1 181 LEU n 
1 182 GLY n 
1 183 LEU n 
1 184 GLY n 
1 185 LYS n 
1 186 VAL n 
1 187 ALA n 
1 188 ILE n 
1 189 ILE n 
1 190 ASP n 
1 191 TRP n 
1 192 ASP n 
1 193 VAL n 
1 194 HIS n 
1 195 HIS n 
1 196 GLY n 
1 197 ASN n 
1 198 GLY n 
1 199 THR n 
1 200 GLN n 
1 201 HIS n 
1 202 ILE n 
1 203 TYR n 
1 204 LEU n 
1 205 GLN n 
1 206 ARG n 
1 207 ASP n 
1 208 ASP n 
1 209 VAL n 
1 210 LEU n 
1 211 THR n 
1 212 ILE n 
1 213 SER n 
1 214 LEU n 
1 215 HIS n 
1 216 GLN n 
1 217 ASP n 
1 218 GLY n 
1 219 CYS n 
1 220 PHE n 
1 221 PRO n 
1 222 PRO n 
1 223 GLY n 
1 224 TYR n 
1 225 ALA n 
1 226 GLY n 
1 227 GLU n 
1 228 ASP n 
1 229 ASP n 
1 230 ARG n 
1 231 GLY n 
1 232 VAL n 
1 233 GLY n 
1 234 ALA n 
1 235 GLY n 
1 236 GLU n 
1 237 GLY n 
1 238 TYR n 
1 239 ASN n 
1 240 ILE n 
1 241 ASN n 
1 242 ILE n 
1 243 PRO n 
1 244 LEU n 
1 245 LEU n 
1 246 ALA n 
1 247 GLY n 
1 248 ALA n 
1 249 GLY n 
1 250 ASP n 
1 251 ASP n 
1 252 SER n 
1 253 TRP n 
1 254 ARG n 
1 255 TYR n 
1 256 ALA n 
1 257 LEU n 
1 258 GLU n 
1 259 THR n 
1 260 ILE n 
1 261 VAL n 
1 262 ILE n 
1 263 PRO n 
1 264 ALA n 
1 265 LEU n 
1 266 ALA n 
1 267 ARG n 
1 268 PHE n 
1 269 GLU n 
1 270 PRO n 
1 271 GLU n 
1 272 LEU n 
1 273 ILE n 
1 274 ILE n 
1 275 ILE n 
1 276 ALA n 
1 277 CYS n 
1 278 GLY n 
1 279 TYR n 
1 280 ASP n 
1 281 ALA n 
1 282 ASN n 
1 283 ALA n 
1 284 MET n 
1 285 ASP n 
1 286 PRO n 
1 287 LEU n 
1 288 ALA n 
1 289 ARG n 
1 290 MET n 
1 291 GLN n 
1 292 LEU n 
1 293 HIS n 
1 294 SER n 
1 295 ASP n 
1 296 SER n 
1 297 PHE n 
1 298 ARG n 
1 299 ALA n 
1 300 MET n 
1 301 THR n 
1 302 GLU n 
1 303 GLN n 
1 304 VAL n 
1 305 GLN n 
1 306 GLN n 
1 307 ALA n 
1 308 ALA n 
1 309 ASP n 
1 310 ARG n 
1 311 LEU n 
1 312 CYS n 
1 313 GLY n 
1 314 GLY n 
1 315 LYS n 
1 316 LEU n 
1 317 VAL n 
1 318 MET n 
1 319 VAL n 
1 320 HIS n 
1 321 GLU n 
1 322 GLY n 
1 323 GLY n 
1 324 TYR n 
1 325 ALA n 
1 326 GLU n 
1 327 SER n 
1 328 TYR n 
1 329 VAL n 
1 330 PRO n 
1 331 PHE n 
1 332 CYS n 
1 333 GLY n 
1 334 LEU n 
1 335 ALA n 
1 336 VAL n 
1 337 MET n 
1 338 GLU n 
1 339 ALA n 
1 340 LEU n 
1 341 SER n 
1 342 GLY n 
1 343 ILE n 
1 344 ARG n 
1 345 THR n 
1 346 GLU n 
1 347 VAL n 
1 348 GLN n 
1 349 ASP n 
1 350 PRO n 
1 351 LEU n 
1 352 LEU n 
1 353 GLU n 
1 354 PHE n 
1 355 ILE n 
1 356 GLN n 
1 357 GLN n 
1 358 GLN n 
1 359 GLN n 
1 360 PRO n 
1 361 ARG n 
1 362 ALA n 
1 363 THR n 
1 364 PHE n 
1 365 ALA n 
1 366 GLN n 
1 367 PHE n 
1 368 GLN n 
1 369 ARG n 
1 370 GLN n 
1 371 ALA n 
1 372 ILE n 
1 373 ASP n 
1 374 ARG n 
1 375 LEU n 
1 376 ALA n 
1 377 GLN n 
1 378 GLN n 
1 379 PHE n 
1 380 GLY n 
1 381 LEU n 
1 382 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   382 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'hdaH, NCTC10313_02007, NCTC5050_05964' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    NCTC10313 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Klebsiella pneumoniae subsp. ozaenae' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     574 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          Plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       'pET45-b(+)' 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE          ?                                                                             
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE         ?                                                                             
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE       ?                                                                             
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'  ?                                                                             
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE         ?                                                                             
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE        ?                                                                             
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'  ?                                                                             
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE          ?                                                                             
'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL         'GLYCERIN; PROPANE-1,2,3-TRIOL'                                               
'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE        ?                                                                             
'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER            ?                                                                             'H2 O' 
18.015  
ILE 'L-peptide linking' y ISOLEUCINE       ?                                                                             
'C6 H13 N O2'    131.173 
K   non-polymer         . 'POTASSIUM ION'  ?                                                                             'K 1' 
39.098  
LEU 'L-peptide linking' y LEUCINE          ?                                                                             
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE           ?                                                                             
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE       ?                                                                             
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE    ?                                                                             
'C9 H11 N O2'    165.189 
PO4 non-polymer         . 'PHOSPHATE ION'  ?                                                                             'O4 P -3' 
94.971  
PRO 'L-peptide linking' y PROLINE          ?                                                                             
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE           ?                                                                             
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE        ?                                                                             
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN       ?                                                                             
'C11 H12 N2 O2'  204.225 
TSN non-polymer         . 'TRICHOSTATIN A' '7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE' 
'C17 H22 N2 O3'  302.368 
TYR 'L-peptide linking' y TYROSINE         ?                                                                             
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE           ?                                                                             
'C5 H11 N O2'    117.146 
ZN  non-polymer         . 'ZINC ION'       ?                                                                             'Zn 2' 
65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -10 ?   ?   ?   A . n 
A 1 2   ALA 2   -9  ?   ?   ?   A . n 
A 1 3   HIS 3   -8  ?   ?   ?   A . n 
A 1 4   HIS 4   -7  ?   ?   ?   A . n 
A 1 5   HIS 5   -6  ?   ?   ?   A . n 
A 1 6   HIS 6   -5  ?   ?   ?   A . n 
A 1 7   HIS 7   -4  ?   ?   ?   A . n 
A 1 8   HIS 8   -3  ?   ?   ?   A . n 
A 1 9   VAL 9   -2  ?   ?   ?   A . n 
A 1 10  GLY 10  -1  ?   ?   ?   A . n 
A 1 11  THR 11  0   ?   ?   ?   A . n 
A 1 12  MET 12  1   ?   ?   ?   A . n 
A 1 13  LYS 13  2   2   LYS LYS A . n 
A 1 14  ARG 14  3   3   ARG ARG A . n 
A 1 15  LYS 15  4   4   LYS LYS A . n 
A 1 16  THR 16  5   5   THR THR A . n 
A 1 17  GLY 17  6   6   GLY GLY A . n 
A 1 18  PHE 18  7   7   PHE PHE A . n 
A 1 19  PHE 19  8   8   PHE PHE A . n 
A 1 20  PHE 20  9   9   PHE PHE A . n 
A 1 21  ASP 21  10  10  ASP ASP A . n 
A 1 22  GLU 22  11  11  GLU GLU A . n 
A 1 23  ARG 23  12  12  ARG ARG A . n 
A 1 24  CYS 24  13  13  CYS CYS A . n 
A 1 25  PHE 25  14  14  PHE PHE A . n 
A 1 26  TRP 26  15  15  TRP TRP A . n 
A 1 27  HIS 27  16  16  HIS HIS A . n 
A 1 28  SER 28  17  17  SER SER A . n 
A 1 29  THR 29  18  18  THR THR A . n 
A 1 30  GLY 30  19  19  GLY GLY A . n 
A 1 31  LEU 31  20  20  LEU LEU A . n 
A 1 32  HIS 32  21  21  HIS HIS A . n 
A 1 33  ALA 33  22  22  ALA ALA A . n 
A 1 34  VAL 34  23  23  VAL VAL A . n 
A 1 35  THR 35  24  24  THR THR A . n 
A 1 36  LEU 36  25  25  LEU LEU A . n 
A 1 37  PRO 37  26  26  PRO PRO A . n 
A 1 38  VAL 38  27  27  VAL VAL A . n 
A 1 39  GLY 39  28  28  GLY GLY A . n 
A 1 40  GLY 40  29  29  GLY GLY A . n 
A 1 41  TRP 41  30  30  TRP TRP A . n 
A 1 42  VAL 42  31  31  VAL VAL A . n 
A 1 43  GLN 43  32  32  GLN GLN A . n 
A 1 44  PRO 44  33  33  PRO PRO A . n 
A 1 45  PRO 45  34  34  PRO PRO A . n 
A 1 46  ALA 46  35  35  ALA ALA A . n 
A 1 47  GLY 47  36  36  GLY GLY A . n 
A 1 48  GLY 48  37  37  GLY GLY A . n 
A 1 49  GLY 49  38  38  GLY GLY A . n 
A 1 50  HIS 50  39  39  HIS HIS A . n 
A 1 51  ALA 51  40  40  ALA ALA A . n 
A 1 52  GLU 52  41  41  GLU GLU A . n 
A 1 53  SER 53  42  42  SER SER A . n 
A 1 54  PRO 54  43  43  PRO PRO A . n 
A 1 55  GLU 55  44  44  GLU GLU A . n 
A 1 56  THR 56  45  45  THR THR A . n 
A 1 57  LYS 57  46  46  LYS LYS A . n 
A 1 58  ARG 58  47  47  ARG ARG A . n 
A 1 59  ARG 59  48  48  ARG ARG A . n 
A 1 60  MET 60  49  49  MET MET A . n 
A 1 61  LYS 61  50  50  LYS LYS A . n 
A 1 62  ASN 62  51  51  ASN ASN A . n 
A 1 63  LEU 63  52  52  LEU LEU A . n 
A 1 64  MET 64  53  53  MET MET A . n 
A 1 65  ASP 65  54  54  ASP ASP A . n 
A 1 66  VAL 66  55  55  VAL VAL A . n 
A 1 67  SER 67  56  56  SER SER A . n 
A 1 68  GLY 68  57  57  GLY GLY A . n 
A 1 69  LEU 69  58  58  LEU LEU A . n 
A 1 70  THR 70  59  59  THR THR A . n 
A 1 71  PRO 71  60  60  PRO PRO A . n 
A 1 72  GLN 72  61  61  GLN GLN A . n 
A 1 73  LEU 73  62  62  LEU LEU A . n 
A 1 74  ALA 74  63  63  ALA ALA A . n 
A 1 75  LEU 75  64  64  LEU LEU A . n 
A 1 76  ARG 76  65  65  ARG ARG A . n 
A 1 77  SER 77  66  66  SER SER A . n 
A 1 78  ALA 78  67  67  ALA ALA A . n 
A 1 79  ALA 79  68  68  ALA ALA A . n 
A 1 80  PRO 80  69  69  PRO PRO A . n 
A 1 81  ALA 81  70  70  ALA ALA A . n 
A 1 82  SER 82  71  71  SER SER A . n 
A 1 83  LEU 83  72  72  LEU LEU A . n 
A 1 84  GLU 84  73  73  GLU GLU A . n 
A 1 85  ASP 85  74  74  ASP ASP A . n 
A 1 86  LEU 86  75  75  LEU LEU A . n 
A 1 87  ARG 87  76  76  ARG ARG A . n 
A 1 88  ARG 88  77  77  ARG ARG A . n 
A 1 89  ILE 89  78  78  ILE ILE A . n 
A 1 90  HIS 90  79  79  HIS HIS A . n 
A 1 91  PRO 91  80  80  PRO PRO A . n 
A 1 92  ASP 92  81  81  ASP ASP A . n 
A 1 93  SER 93  82  82  SER SER A . n 
A 1 94  TYR 94  83  83  TYR TYR A . n 
A 1 95  LEU 95  84  84  LEU LEU A . n 
A 1 96  GLU 96  85  85  GLU GLU A . n 
A 1 97  ARG 97  86  86  ARG ARG A . n 
A 1 98  PHE 98  87  87  PHE PHE A . n 
A 1 99  LYS 99  88  88  LYS LYS A . n 
A 1 100 ALA 100 89  89  ALA ALA A . n 
A 1 101 ILE 101 90  90  ILE ILE A . n 
A 1 102 SER 102 91  91  SER SER A . n 
A 1 103 ASP 103 92  92  ASP ASP A . n 
A 1 104 ASN 104 93  93  ASN ASN A . n 
A 1 105 GLY 105 94  94  GLY GLY A . n 
A 1 106 GLY 106 95  95  GLY GLY A . n 
A 1 107 GLY 107 96  96  GLY GLY A . n 
A 1 108 MET 108 97  97  MET MET A . n 
A 1 109 LEU 109 98  98  LEU LEU A . n 
A 1 110 GLY 110 99  99  GLY GLY A . n 
A 1 111 LYS 111 100 100 LYS LYS A . n 
A 1 112 GLU 112 101 101 GLU GLU A . n 
A 1 113 ALA 113 102 102 ALA ALA A . n 
A 1 114 PRO 114 103 103 PRO PRO A . n 
A 1 115 LEU 115 104 104 LEU LEU A . n 
A 1 116 GLY 116 105 105 GLY GLY A . n 
A 1 117 PRO 117 106 106 PRO PRO A . n 
A 1 118 GLY 118 107 107 GLY GLY A . n 
A 1 119 SER 119 108 108 SER SER A . n 
A 1 120 TYR 120 109 109 TYR TYR A . n 
A 1 121 GLU 121 110 110 GLU GLU A . n 
A 1 122 ILE 122 111 111 ILE ILE A . n 
A 1 123 ALA 123 112 112 ALA ALA A . n 
A 1 124 CYS 124 113 113 CYS CYS A . n 
A 1 125 LEU 125 114 114 LEU LEU A . n 
A 1 126 SER 126 115 115 SER SER A . n 
A 1 127 ALA 127 116 116 ALA ALA A . n 
A 1 128 GLY 128 117 117 GLY GLY A . n 
A 1 129 LEU 129 118 118 LEU LEU A . n 
A 1 130 ALA 130 119 119 ALA ALA A . n 
A 1 131 CYS 131 120 120 CYS CYS A . n 
A 1 132 ALA 132 121 121 ALA ALA A . n 
A 1 133 ALA 133 122 122 ALA ALA A . n 
A 1 134 VAL 134 123 123 VAL VAL A . n 
A 1 135 GLU 135 124 124 GLU GLU A . n 
A 1 136 ALA 136 125 125 ALA ALA A . n 
A 1 137 VAL 137 126 126 VAL VAL A . n 
A 1 138 LEU 138 127 127 LEU LEU A . n 
A 1 139 LYS 139 128 128 LYS LYS A . n 
A 1 140 GLY 140 129 129 GLY GLY A . n 
A 1 141 GLU 141 130 130 GLU GLU A . n 
A 1 142 LEU 142 131 131 LEU LEU A . n 
A 1 143 ASP 143 132 132 ASP ASP A . n 
A 1 144 ASN 144 133 133 ASN ASN A . n 
A 1 145 ALA 145 134 134 ALA ALA A . n 
A 1 146 TYR 146 135 135 TYR TYR A . n 
A 1 147 SER 147 136 136 SER SER A . n 
A 1 148 LEU 148 137 137 LEU LEU A . n 
A 1 149 SER 149 138 138 SER SER A . n 
A 1 150 ARG 150 139 139 ARG ARG A . n 
A 1 151 PRO 151 140 140 PRO PRO A . n 
A 1 152 PRO 152 141 141 PRO PRO A . n 
A 1 153 GLY 153 142 142 GLY GLY A . n 
A 1 154 HIS 154 143 143 HIS HIS A . n 
A 1 155 HIS 155 144 144 HIS HIS A . n 
A 1 156 CYS 156 145 145 CYS CYS A . n 
A 1 157 LEU 157 146 146 LEU LEU A . n 
A 1 158 PRO 158 147 147 PRO PRO A . n 
A 1 159 ASP 159 148 148 ASP ASP A . n 
A 1 160 GLN 160 149 149 GLN GLN A . n 
A 1 161 SER 161 150 150 SER SER A . n 
A 1 162 MET 162 151 151 MET MET A . n 
A 1 163 GLY 163 152 152 GLY GLY A . n 
A 1 164 PHE 164 153 153 PHE PHE A . n 
A 1 165 CYS 165 154 154 CYS CYS A . n 
A 1 166 PHE 166 155 155 PHE PHE A . n 
A 1 167 LEU 167 156 156 LEU LEU A . n 
A 1 168 ALA 168 157 157 ALA ALA A . n 
A 1 169 ASN 169 158 158 ASN ASN A . n 
A 1 170 ILE 170 159 159 ILE ILE A . n 
A 1 171 PRO 171 160 160 PRO PRO A . n 
A 1 172 ILE 172 161 161 ILE ILE A . n 
A 1 173 ALA 173 162 162 ALA ALA A . n 
A 1 174 VAL 174 163 163 VAL VAL A . n 
A 1 175 GLU 175 164 164 GLU GLU A . n 
A 1 176 ARG 176 165 165 ARG ARG A . n 
A 1 177 ALA 177 166 166 ALA ALA A . n 
A 1 178 LYS 178 167 167 LYS LYS A . n 
A 1 179 ALA 179 168 168 ALA ALA A . n 
A 1 180 GLN 180 169 169 GLN GLN A . n 
A 1 181 LEU 181 170 170 LEU LEU A . n 
A 1 182 GLY 182 171 171 GLY GLY A . n 
A 1 183 LEU 183 172 172 LEU LEU A . n 
A 1 184 GLY 184 173 173 GLY GLY A . n 
A 1 185 LYS 185 174 174 LYS LYS A . n 
A 1 186 VAL 186 175 175 VAL VAL A . n 
A 1 187 ALA 187 176 176 ALA ALA A . n 
A 1 188 ILE 188 177 177 ILE ILE A . n 
A 1 189 ILE 189 178 178 ILE ILE A . n 
A 1 190 ASP 190 179 179 ASP ASP A . n 
A 1 191 TRP 191 180 180 TRP TRP A . n 
A 1 192 ASP 192 181 181 ASP ASP A . n 
A 1 193 VAL 193 182 182 VAL VAL A . n 
A 1 194 HIS 194 183 183 HIS HIS A . n 
A 1 195 HIS 195 184 184 HIS HIS A . n 
A 1 196 GLY 196 185 185 GLY GLY A . n 
A 1 197 ASN 197 186 186 ASN ASN A . n 
A 1 198 GLY 198 187 187 GLY GLY A . n 
A 1 199 THR 199 188 188 THR THR A . n 
A 1 200 GLN 200 189 189 GLN GLN A . n 
A 1 201 HIS 201 190 190 HIS HIS A . n 
A 1 202 ILE 202 191 191 ILE ILE A . n 
A 1 203 TYR 203 192 192 TYR TYR A . n 
A 1 204 LEU 204 193 193 LEU LEU A . n 
A 1 205 GLN 205 194 194 GLN GLN A . n 
A 1 206 ARG 206 195 195 ARG ARG A . n 
A 1 207 ASP 207 196 196 ASP ASP A . n 
A 1 208 ASP 208 197 197 ASP ASP A . n 
A 1 209 VAL 209 198 198 VAL VAL A . n 
A 1 210 LEU 210 199 199 LEU LEU A . n 
A 1 211 THR 211 200 200 THR THR A . n 
A 1 212 ILE 212 201 201 ILE ILE A . n 
A 1 213 SER 213 202 202 SER SER A . n 
A 1 214 LEU 214 203 203 LEU LEU A . n 
A 1 215 HIS 215 204 204 HIS HIS A . n 
A 1 216 GLN 216 205 205 GLN GLN A . n 
A 1 217 ASP 217 206 206 ASP ASP A . n 
A 1 218 GLY 218 207 207 GLY GLY A . n 
A 1 219 CYS 219 208 208 CYS CYS A . n 
A 1 220 PHE 220 209 209 PHE PHE A . n 
A 1 221 PRO 221 210 210 PRO PRO A . n 
A 1 222 PRO 222 211 211 PRO PRO A . n 
A 1 223 GLY 223 212 212 GLY GLY A . n 
A 1 224 TYR 224 213 213 TYR TYR A . n 
A 1 225 ALA 225 214 214 ALA ALA A . n 
A 1 226 GLY 226 215 215 GLY GLY A . n 
A 1 227 GLU 227 216 216 GLU GLU A . n 
A 1 228 ASP 228 217 217 ASP ASP A . n 
A 1 229 ASP 229 218 218 ASP ASP A . n 
A 1 230 ARG 230 219 219 ARG ARG A . n 
A 1 231 GLY 231 220 220 GLY GLY A . n 
A 1 232 VAL 232 221 221 VAL VAL A . n 
A 1 233 GLY 233 222 222 GLY GLY A . n 
A 1 234 ALA 234 223 223 ALA ALA A . n 
A 1 235 GLY 235 224 224 GLY GLY A . n 
A 1 236 GLU 236 225 225 GLU GLU A . n 
A 1 237 GLY 237 226 226 GLY GLY A . n 
A 1 238 TYR 238 227 227 TYR TYR A . n 
A 1 239 ASN 239 228 228 ASN ASN A . n 
A 1 240 ILE 240 229 229 ILE ILE A . n 
A 1 241 ASN 241 230 230 ASN ASN A . n 
A 1 242 ILE 242 231 231 ILE ILE A . n 
A 1 243 PRO 243 232 232 PRO PRO A . n 
A 1 244 LEU 244 233 233 LEU LEU A . n 
A 1 245 LEU 245 234 234 LEU LEU A . n 
A 1 246 ALA 246 235 235 ALA ALA A . n 
A 1 247 GLY 247 236 236 GLY GLY A . n 
A 1 248 ALA 248 237 237 ALA ALA A . n 
A 1 249 GLY 249 238 238 GLY GLY A . n 
A 1 250 ASP 250 239 239 ASP ASP A . n 
A 1 251 ASP 251 240 240 ASP ASP A . n 
A 1 252 SER 252 241 241 SER SER A . n 
A 1 253 TRP 253 242 242 TRP TRP A . n 
A 1 254 ARG 254 243 243 ARG ARG A . n 
A 1 255 TYR 255 244 244 TYR TYR A . n 
A 1 256 ALA 256 245 245 ALA ALA A . n 
A 1 257 LEU 257 246 246 LEU LEU A . n 
A 1 258 GLU 258 247 247 GLU GLU A . n 
A 1 259 THR 259 248 248 THR THR A . n 
A 1 260 ILE 260 249 249 ILE ILE A . n 
A 1 261 VAL 261 250 250 VAL VAL A . n 
A 1 262 ILE 262 251 251 ILE ILE A . n 
A 1 263 PRO 263 252 252 PRO PRO A . n 
A 1 264 ALA 264 253 253 ALA ALA A . n 
A 1 265 LEU 265 254 254 LEU LEU A . n 
A 1 266 ALA 266 255 255 ALA ALA A . n 
A 1 267 ARG 267 256 256 ARG ARG A . n 
A 1 268 PHE 268 257 257 PHE PHE A . n 
A 1 269 GLU 269 258 258 GLU GLU A . n 
A 1 270 PRO 270 259 259 PRO PRO A . n 
A 1 271 GLU 271 260 260 GLU GLU A . n 
A 1 272 LEU 272 261 261 LEU LEU A . n 
A 1 273 ILE 273 262 262 ILE ILE A . n 
A 1 274 ILE 274 263 263 ILE ILE A . n 
A 1 275 ILE 275 264 264 ILE ILE A . n 
A 1 276 ALA 276 265 265 ALA ALA A . n 
A 1 277 CYS 277 266 266 CYS CYS A . n 
A 1 278 GLY 278 267 267 GLY GLY A . n 
A 1 279 TYR 279 268 268 TYR TYR A . n 
A 1 280 ASP 280 269 269 ASP ASP A . n 
A 1 281 ALA 281 270 270 ALA ALA A . n 
A 1 282 ASN 282 271 271 ASN ASN A . n 
A 1 283 ALA 283 272 272 ALA ALA A . n 
A 1 284 MET 284 273 273 MET MET A . n 
A 1 285 ASP 285 274 274 ASP ASP A . n 
A 1 286 PRO 286 275 275 PRO PRO A . n 
A 1 287 LEU 287 276 276 LEU LEU A . n 
A 1 288 ALA 288 277 277 ALA ALA A . n 
A 1 289 ARG 289 278 278 ARG ARG A . n 
A 1 290 MET 290 279 279 MET MET A . n 
A 1 291 GLN 291 280 280 GLN GLN A . n 
A 1 292 LEU 292 281 281 LEU LEU A . n 
A 1 293 HIS 293 282 282 HIS HIS A . n 
A 1 294 SER 294 283 283 SER SER A . n 
A 1 295 ASP 295 284 284 ASP ASP A . n 
A 1 296 SER 296 285 285 SER SER A . n 
A 1 297 PHE 297 286 286 PHE PHE A . n 
A 1 298 ARG 298 287 287 ARG ARG A . n 
A 1 299 ALA 299 288 288 ALA ALA A . n 
A 1 300 MET 300 289 289 MET MET A . n 
A 1 301 THR 301 290 290 THR THR A . n 
A 1 302 GLU 302 291 291 GLU GLU A . n 
A 1 303 GLN 303 292 292 GLN GLN A . n 
A 1 304 VAL 304 293 293 VAL VAL A . n 
A 1 305 GLN 305 294 294 GLN GLN A . n 
A 1 306 GLN 306 295 295 GLN GLN A . n 
A 1 307 ALA 307 296 296 ALA ALA A . n 
A 1 308 ALA 308 297 297 ALA ALA A . n 
A 1 309 ASP 309 298 298 ASP ASP A . n 
A 1 310 ARG 310 299 299 ARG ARG A . n 
A 1 311 LEU 311 300 300 LEU LEU A . n 
A 1 312 CYS 312 301 301 CYS CYS A . n 
A 1 313 GLY 313 302 302 GLY GLY A . n 
A 1 314 GLY 314 303 303 GLY GLY A . n 
A 1 315 LYS 315 304 304 LYS LYS A . n 
A 1 316 LEU 316 305 305 LEU LEU A . n 
A 1 317 VAL 317 306 306 VAL VAL A . n 
A 1 318 MET 318 307 307 MET MET A . n 
A 1 319 VAL 319 308 308 VAL VAL A . n 
A 1 320 HIS 320 309 309 HIS HIS A . n 
A 1 321 GLU 321 310 310 GLU GLU A . n 
A 1 322 GLY 322 311 311 GLY GLY A . n 
A 1 323 GLY 323 312 312 GLY GLY A . n 
A 1 324 TYR 324 313 313 TYR TYR A . n 
A 1 325 ALA 325 314 314 ALA ALA A . n 
A 1 326 GLU 326 315 315 GLU GLU A . n 
A 1 327 SER 327 316 316 SER SER A . n 
A 1 328 TYR 328 317 317 TYR TYR A . n 
A 1 329 VAL 329 318 318 VAL VAL A . n 
A 1 330 PRO 330 319 319 PRO PRO A . n 
A 1 331 PHE 331 320 320 PHE PHE A . n 
A 1 332 CYS 332 321 321 CYS CYS A . n 
A 1 333 GLY 333 322 322 GLY GLY A . n 
A 1 334 LEU 334 323 323 LEU LEU A . n 
A 1 335 ALA 335 324 324 ALA ALA A . n 
A 1 336 VAL 336 325 325 VAL VAL A . n 
A 1 337 MET 337 326 326 MET MET A . n 
A 1 338 GLU 338 327 327 GLU GLU A . n 
A 1 339 ALA 339 328 328 ALA ALA A . n 
A 1 340 LEU 340 329 329 LEU LEU A . n 
A 1 341 SER 341 330 330 SER SER A . n 
A 1 342 GLY 342 331 331 GLY GLY A . n 
A 1 343 ILE 343 332 332 ILE ILE A . n 
A 1 344 ARG 344 333 333 ARG ARG A . n 
A 1 345 THR 345 334 334 THR THR A . n 
A 1 346 GLU 346 335 335 GLU GLU A . n 
A 1 347 VAL 347 336 336 VAL VAL A . n 
A 1 348 GLN 348 337 337 GLN GLN A . n 
A 1 349 ASP 349 338 338 ASP ASP A . n 
A 1 350 PRO 350 339 339 PRO PRO A . n 
A 1 351 LEU 351 340 340 LEU LEU A . n 
A 1 352 LEU 352 341 341 LEU LEU A . n 
A 1 353 GLU 353 342 342 GLU GLU A . n 
A 1 354 PHE 354 343 343 PHE PHE A . n 
A 1 355 ILE 355 344 344 ILE ILE A . n 
A 1 356 GLN 356 345 345 GLN GLN A . n 
A 1 357 GLN 357 346 346 GLN GLN A . n 
A 1 358 GLN 358 347 347 GLN GLN A . n 
A 1 359 GLN 359 348 348 GLN GLN A . n 
A 1 360 PRO 360 349 349 PRO PRO A . n 
A 1 361 ARG 361 350 350 ARG ARG A . n 
A 1 362 ALA 362 351 351 ALA ALA A . n 
A 1 363 THR 363 352 352 THR THR A . n 
A 1 364 PHE 364 353 353 PHE PHE A . n 
A 1 365 ALA 365 354 354 ALA ALA A . n 
A 1 366 GLN 366 355 355 GLN GLN A . n 
A 1 367 PHE 367 356 356 PHE PHE A . n 
A 1 368 GLN 368 357 357 GLN GLN A . n 
A 1 369 ARG 369 358 358 ARG ARG A . n 
A 1 370 GLN 370 359 359 GLN GLN A . n 
A 1 371 ALA 371 360 360 ALA ALA A . n 
A 1 372 ILE 372 361 361 ILE ILE A . n 
A 1 373 ASP 373 362 362 ASP ASP A . n 
A 1 374 ARG 374 363 363 ARG ARG A . n 
A 1 375 LEU 375 364 364 LEU LEU A . n 
A 1 376 ALA 376 365 365 ALA ALA A . n 
A 1 377 GLN 377 366 366 GLN GLN A . n 
A 1 378 GLN 378 367 367 GLN GLN A . n 
A 1 379 PHE 379 368 368 PHE PHE A . n 
A 1 380 GLY 380 369 369 GLY GLY A . n 
A 1 381 LEU 381 370 370 LEU LEU A . n 
A 1 382 GLN 382 371 371 GLN GLN A . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 ZN  ? ? ZN  ? ? 'SUBJECT OF INVESTIGATION' ? 
2 TSN ? ? TSN ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 K   1   401 1   K   K   A . 
C 2 K   1   402 2   K   K   A . 
D 3 ZN  1   403 3   ZN  ZN  A . 
E 4 PO4 1   404 4   PO4 PO4 A . 
F 5 TSN 1   405 1   TSN TSN A . 
G 6 GOL 1   406 2   GOL GOL A . 
H 6 GOL 1   407 3   GOL GOL A . 
I 7 HOH 1   501 106 HOH HOH A . 
I 7 HOH 2   502 55  HOH HOH A . 
I 7 HOH 3   503 28  HOH HOH A . 
I 7 HOH 4   504 29  HOH HOH A . 
I 7 HOH 5   505 105 HOH HOH A . 
I 7 HOH 6   506 71  HOH HOH A . 
I 7 HOH 7   507 61  HOH HOH A . 
I 7 HOH 8   508 116 HOH HOH A . 
I 7 HOH 9   509 78  HOH HOH A . 
I 7 HOH 10  510 118 HOH HOH A . 
I 7 HOH 11  511 95  HOH HOH A . 
I 7 HOH 12  512 100 HOH HOH A . 
I 7 HOH 13  513 30  HOH HOH A . 
I 7 HOH 14  514 41  HOH HOH A . 
I 7 HOH 15  515 67  HOH HOH A . 
I 7 HOH 16  516 25  HOH HOH A . 
I 7 HOH 17  517 68  HOH HOH A . 
I 7 HOH 18  518 44  HOH HOH A . 
I 7 HOH 19  519 39  HOH HOH A . 
I 7 HOH 20  520 96  HOH HOH A . 
I 7 HOH 21  521 15  HOH HOH A . 
I 7 HOH 22  522 26  HOH HOH A . 
I 7 HOH 23  523 72  HOH HOH A . 
I 7 HOH 24  524 9   HOH HOH A . 
I 7 HOH 25  525 7   HOH HOH A . 
I 7 HOH 26  526 75  HOH HOH A . 
I 7 HOH 27  527 32  HOH HOH A . 
I 7 HOH 28  528 90  HOH HOH A . 
I 7 HOH 29  529 92  HOH HOH A . 
I 7 HOH 30  530 97  HOH HOH A . 
I 7 HOH 31  531 16  HOH HOH A . 
I 7 HOH 32  532 23  HOH HOH A . 
I 7 HOH 33  533 58  HOH HOH A . 
I 7 HOH 34  534 35  HOH HOH A . 
I 7 HOH 35  535 69  HOH HOH A . 
I 7 HOH 36  536 43  HOH HOH A . 
I 7 HOH 37  537 112 HOH HOH A . 
I 7 HOH 38  538 86  HOH HOH A . 
I 7 HOH 39  539 82  HOH HOH A . 
I 7 HOH 40  540 12  HOH HOH A . 
I 7 HOH 41  541 93  HOH HOH A . 
I 7 HOH 42  542 33  HOH HOH A . 
I 7 HOH 43  543 45  HOH HOH A . 
I 7 HOH 44  544 52  HOH HOH A . 
I 7 HOH 45  545 20  HOH HOH A . 
I 7 HOH 46  546 83  HOH HOH A . 
I 7 HOH 47  547 8   HOH HOH A . 
I 7 HOH 48  548 91  HOH HOH A . 
I 7 HOH 49  549 11  HOH HOH A . 
I 7 HOH 50  550 2   HOH HOH A . 
I 7 HOH 51  551 89  HOH HOH A . 
I 7 HOH 52  552 62  HOH HOH A . 
I 7 HOH 53  553 81  HOH HOH A . 
I 7 HOH 54  554 51  HOH HOH A . 
I 7 HOH 55  555 3   HOH HOH A . 
I 7 HOH 56  556 117 HOH HOH A . 
I 7 HOH 57  557 27  HOH HOH A . 
I 7 HOH 58  558 54  HOH HOH A . 
I 7 HOH 59  559 101 HOH HOH A . 
I 7 HOH 60  560 84  HOH HOH A . 
I 7 HOH 61  561 4   HOH HOH A . 
I 7 HOH 62  562 119 HOH HOH A . 
I 7 HOH 63  563 22  HOH HOH A . 
I 7 HOH 64  564 37  HOH HOH A . 
I 7 HOH 65  565 50  HOH HOH A . 
I 7 HOH 66  566 56  HOH HOH A . 
I 7 HOH 67  567 53  HOH HOH A . 
I 7 HOH 68  568 6   HOH HOH A . 
I 7 HOH 69  569 36  HOH HOH A . 
I 7 HOH 70  570 110 HOH HOH A . 
I 7 HOH 71  571 109 HOH HOH A . 
I 7 HOH 72  572 34  HOH HOH A . 
I 7 HOH 73  573 14  HOH HOH A . 
I 7 HOH 74  574 85  HOH HOH A . 
I 7 HOH 75  575 103 HOH HOH A . 
I 7 HOH 76  576 38  HOH HOH A . 
I 7 HOH 77  577 77  HOH HOH A . 
I 7 HOH 78  578 42  HOH HOH A . 
I 7 HOH 79  579 65  HOH HOH A . 
I 7 HOH 80  580 24  HOH HOH A . 
I 7 HOH 81  581 102 HOH HOH A . 
I 7 HOH 82  582 21  HOH HOH A . 
I 7 HOH 83  583 64  HOH HOH A . 
I 7 HOH 84  584 63  HOH HOH A . 
I 7 HOH 85  585 18  HOH HOH A . 
I 7 HOH 86  586 98  HOH HOH A . 
I 7 HOH 87  587 5   HOH HOH A . 
I 7 HOH 88  588 47  HOH HOH A . 
I 7 HOH 89  589 57  HOH HOH A . 
I 7 HOH 90  590 66  HOH HOH A . 
I 7 HOH 91  591 74  HOH HOH A . 
I 7 HOH 92  592 40  HOH HOH A . 
I 7 HOH 93  593 31  HOH HOH A . 
I 7 HOH 94  594 70  HOH HOH A . 
I 7 HOH 95  595 48  HOH HOH A . 
I 7 HOH 96  596 79  HOH HOH A . 
I 7 HOH 97  597 13  HOH HOH A . 
I 7 HOH 98  598 99  HOH HOH A . 
I 7 HOH 99  599 59  HOH HOH A . 
I 7 HOH 100 600 49  HOH HOH A . 
I 7 HOH 101 601 10  HOH HOH A . 
I 7 HOH 102 602 19  HOH HOH A . 
I 7 HOH 103 603 80  HOH HOH A . 
I 7 HOH 104 604 17  HOH HOH A . 
I 7 HOH 105 605 60  HOH HOH A . 
I 7 HOH 106 606 46  HOH HOH A . 
I 7 HOH 107 607 114 HOH HOH A . 
I 7 HOH 108 608 73  HOH HOH A . 
I 7 HOH 109 609 94  HOH HOH A . 
I 7 HOH 110 610 1   HOH HOH A . 
I 7 HOH 111 611 104 HOH HOH A . 
I 7 HOH 112 612 87  HOH HOH A . 
I 7 HOH 113 613 111 HOH HOH A . 
I 7 HOH 114 614 113 HOH HOH A . 
I 7 HOH 115 615 115 HOH HOH A . 
I 7 HOH 116 616 107 HOH HOH A . 
I 7 HOH 117 617 108 HOH HOH A . 
I 7 HOH 118 618 76  HOH HOH A . 
I 7 HOH 119 619 88  HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0425                       1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0425                       2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? 'Mar 15, 2019  BUILT=20190315' 3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? 'Mar 15, 2019  BUILT=20190315' 4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .                              5 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GN7 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     146.57 
_cell.length_a_esd                 ? 
_cell.length_b                     146.57 
_cell.length_b_esd                 ? 
_cell.length_c                     146.57 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GN7 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                197 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'I 2 3' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GN7 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.16 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          61.05 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '12% (w/v) PEG 8000, 10% (v/v) glycerol and 0.5M KCl' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      mirror 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2019-10-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.0 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.0 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   'P13 (MX1)' 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, EMBL c/o DESY' 
# 
_reflns.B_iso_Wilson_estimate                          39.05 
_reflns.entry_id                                       9GN7 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.18 
_reflns.d_resolution_low                               47 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     27454 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     -3 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                1.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          10.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.18 
_reflns_shell.d_res_low                                     2.25 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.5 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2367 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.832 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.9 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.000 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            0.000 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.000 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               43.205 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.975 
_refine.correlation_coeff_Fo_to_Fc_free          0.962 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9GN7 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.180 
_refine.ls_d_res_low                             46.393 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     27437 
_refine.ls_number_reflns_R_free                  1378 
_refine.ls_number_reflns_R_work                  26059 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.978 
_refine.ls_percent_reflns_R_free                 5.022 
_refine.ls_R_factor_all                          0.150 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1862 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1478 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      0.195 
_refine.ls_wR_factor_R_work                      0.152 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.151 
_refine.pdbx_overall_ESU_R_Free                  0.140 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             4.187 
_refine.overall_SU_ML                            0.103 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    0.9835 
_refine.pdbx_average_fsc_free                    0.9728 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.180 
_refine_hist.d_res_low                        46.393 
_refine_hist.number_atoms_solvent             119 
_refine_hist.number_atoms_total               2983 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2822 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         42 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.014  0.012  2926 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  2720 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 2.236  1.813  3963 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.756  1.745  6261 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.855  5.000  369  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 11.793 5.000  28   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 14.005 10.000 457  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.486 10.000 135  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.106  0.200  422  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.013  0.020  3545 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  683  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.246  0.200  627  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.194  0.200  2525 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.191  0.200  1443 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.086  0.200  1650 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.183  0.200  106  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.039  0.200  1    ? r_symmetry_xyhbond_nbd_other   ? ? 
'X-RAY DIFFRACTION' ? 0.210  0.200  11   ? r_metal_ion_refined            ? ? 
'X-RAY DIFFRACTION' ? 0.113  0.200  13   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.139  0.200  95   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.056  0.200  18   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 4.944  4.003  1479 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.943  4.003  1479 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 6.392  7.149  1847 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 6.392  7.154  1848 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 7.262  4.601  1447 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 7.262  4.603  1448 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 9.272  8.127  2116 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 9.270  8.128  2117 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 10.172 37.407 3240 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 10.202 37.263 3219 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.180 2.237  2008 . 88  1919 99.9502  . 0.222 . . 0.221 . . . . . 0.209 . 20 . 0.971 0.966 0.239 
'X-RAY DIFFRACTION' 2.237 2.298  1976 . 104 1872 100.0000 . 0.224 . . 0.222 . . . . . 0.206 . 20 . 0.970 0.957 0.257 
'X-RAY DIFFRACTION' 2.298 2.364  1906 . 107 1799 100.0000 . 0.210 . . 0.209 . . . . . 0.194 . 20 . 0.974 0.968 0.225 
'X-RAY DIFFRACTION' 2.364 2.437  1828 . 89  1739 100.0000 . 0.197 . . 0.195 . . . . . 0.178 . 20 . 0.979 0.964 0.233 
'X-RAY DIFFRACTION' 2.437 2.516  1801 . 103 1698 100.0000 . 0.184 . . 0.182 . . . . . 0.165 . 20 . 0.983 0.967 0.232 
'X-RAY DIFFRACTION' 2.516 2.604  1735 . 73  1662 100.0000 . 0.185 . . 0.183 . . . . . 0.167 . 20 . 0.985 0.975 0.223 
'X-RAY DIFFRACTION' 2.604 2.702  1683 . 88  1595 100.0000 . 0.162 . . 0.158 . . . . . 0.144 . 20 . 0.986 0.966 0.236 
'X-RAY DIFFRACTION' 2.702 2.812  1595 . 79  1516 100.0000 . 0.153 . . 0.151 . . . . . 0.139 . 20 . 0.986 0.974 0.203 
'X-RAY DIFFRACTION' 2.812 2.937  1545 . 63  1482 100.0000 . 0.152 . . 0.150 . . . . . 0.142 . 20 . 0.986 0.972 0.200 
'X-RAY DIFFRACTION' 2.937 3.080  1497 . 78  1418 99.9332  . 0.161 . . 0.158 . . . . . 0.153 . 20 . 0.985 0.976 0.215 
'X-RAY DIFFRACTION' 3.080 3.245  1424 . 84  1340 100.0000 . 0.165 . . 0.161 . . . . . 0.159 . 20 . 0.984 0.970 0.226 
'X-RAY DIFFRACTION' 3.245 3.441  1320 . 60  1260 100.0000 . 0.162 . . 0.160 . . . . . 0.163 . 20 . 0.987 0.972 0.201 
'X-RAY DIFFRACTION' 3.441 3.677  1277 . 66  1211 100.0000 . 0.155 . . 0.154 . . . . . 0.160 . 20 . 0.988 0.982 0.179 
'X-RAY DIFFRACTION' 3.677 3.970  1185 . 57  1128 100.0000 . 0.131 . . 0.130 . . . . . 0.141 . 20 . 0.992 0.983 0.165 
'X-RAY DIFFRACTION' 3.970 4.346  1083 . 54  1029 100.0000 . 0.110 . . 0.109 . . . . . 0.125 . 20 . 0.994 0.990 0.130 
'X-RAY DIFFRACTION' 4.346 4.853  992  . 58  934  100.0000 . 0.091 . . 0.089 . . . . . 0.107 . 20 . 0.996 0.992 0.124 
'X-RAY DIFFRACTION' 4.853 5.594  867  . 40  827  100.0000 . 0.117 . . 0.115 . . . . . 0.133 . 20 . 0.994 0.988 0.167 
'X-RAY DIFFRACTION' 5.594 6.826  756  . 25  731  100.0000 . 0.164 . . 0.162 . . . . . 0.187 . 20 . 0.988 0.974 0.218 
'X-RAY DIFFRACTION' 6.826 9.551  596  . 40  556  100.0000 . 0.114 . . 0.112 . . . . . 0.143 . 20 . 0.993 0.990 0.140 
'X-RAY DIFFRACTION' 9.551 46.393 365  . 22  343  100.0000 . 0.164 . . 0.163 . . . . . 0.205 . 20 . 0.982 0.980 0.170 
# 
_struct.entry_id                     9GN7 
_struct.title                        
'Crystal Structure of Deacetylase (HdaH) from Klebsiella pneumoniae subsp. ozaenae in Complex with the inhibitor TSA' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GN7 
_struct_keywords.text            'Inhibitor, TSA, Deacetylase with TSA, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 5 ? 
G N N 6 ? 
H N N 6 ? 
I N N 7 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A377Z5F6_KLEPO 
_struct_ref.pdbx_db_accession          A0A377Z5F6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKRKTGFFFDERCFWHSTGLHAVTLPVGGWVQPPAGGGHAESPETKRRMKNLMDVSGLTPQLALRSAAPASLEDLRRIHP
DSYLERFKAISDNGGGMLGKEAPLGPGSYEIACLSAGLACAAVEAVLKGELDNAYSLSRPPGHHCLPDQSMGFCFLANIP
IAVERAKAQLGLGKVAIIDWDVHHGNGTQHIYLQRDDVLTISLHQDGCFPPGYAGEDDRGVGAGEGYNINIPLLAGAGDD
SWRYALETIVIPALARFEPELIIIACGYDANAMDPLARMQLHSDSFRAMTEQVQQAADRLCGGKLVMVHEGGYAESYVPF
CGLAVMEALSGIRTEVQDPLLEFIQQQQPRATFAQFQRQAIDRLAQQFGLQ
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9GN7 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 12 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 382 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A377Z5F6 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  371 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       371 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9GN7 MET A 1  ? UNP A0A377Z5F6 ? ? 'initiating methionine' -10 1  
1 9GN7 ALA A 2  ? UNP A0A377Z5F6 ? ? 'expression tag'        -9  2  
1 9GN7 HIS A 3  ? UNP A0A377Z5F6 ? ? 'expression tag'        -8  3  
1 9GN7 HIS A 4  ? UNP A0A377Z5F6 ? ? 'expression tag'        -7  4  
1 9GN7 HIS A 5  ? UNP A0A377Z5F6 ? ? 'expression tag'        -6  5  
1 9GN7 HIS A 6  ? UNP A0A377Z5F6 ? ? 'expression tag'        -5  6  
1 9GN7 HIS A 7  ? UNP A0A377Z5F6 ? ? 'expression tag'        -4  7  
1 9GN7 HIS A 8  ? UNP A0A377Z5F6 ? ? 'expression tag'        -3  8  
1 9GN7 VAL A 9  ? UNP A0A377Z5F6 ? ? 'expression tag'        -2  9  
1 9GN7 GLY A 10 ? UNP A0A377Z5F6 ? ? 'expression tag'        -1  10 
1 9GN7 THR A 11 ? UNP A0A377Z5F6 ? ? 'expression tag'        0   11 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 21700 ? 
1 MORE         -291  ? 
1 'SSA (A^2)'  41780 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2,3,4 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z     1.0000000000  0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000   
2 'crystal symmetry operation' 2_555 -x,-y,z   -1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000   
3 'crystal symmetry operation' 3_556 -x,y,-z+1 -1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 146.5700000000 
4 'crystal symmetry operation' 4_556 x,-y,-z+1 1.0000000000  0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 146.5700000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 21  ? HIS A 27  ? ASP A 10  HIS A 16  5 ? 7  
HELX_P HELX_P2  AA2 PRO A 54  ? SER A 67  ? PRO A 43  SER A 56  1 ? 14 
HELX_P HELX_P3  AA3 LEU A 69  ? LEU A 73  ? LEU A 58  LEU A 62  5 ? 5  
HELX_P HELX_P4  AA4 SER A 82  ? ARG A 88  ? SER A 71  ARG A 77  1 ? 7  
HELX_P HELX_P5  AA5 PRO A 91  ? ASN A 104 ? PRO A 80  ASN A 93  1 ? 14 
HELX_P HELX_P6  AA6 GLY A 118 ? LYS A 139 ? GLY A 107 LYS A 128 1 ? 22 
HELX_P HELX_P7  AA7 ALA A 168 ? LEU A 181 ? ALA A 157 LEU A 170 1 ? 14 
HELX_P HELX_P8  AA8 GLY A 196 ? TYR A 203 ? GLY A 185 TYR A 192 1 ? 8  
HELX_P HELX_P9  AA9 VAL A 232 ? GLU A 236 ? VAL A 221 GLU A 225 5 ? 5  
HELX_P HELX_P10 AB1 GLY A 249 ? ILE A 260 ? GLY A 238 ILE A 249 1 ? 12 
HELX_P HELX_P11 AB2 ILE A 260 ? GLU A 269 ? ILE A 249 GLU A 258 1 ? 10 
HELX_P HELX_P12 AB3 HIS A 293 ? GLY A 313 ? HIS A 282 GLY A 302 1 ? 21 
HELX_P HELX_P13 AB4 TYR A 328 ? GLY A 342 ? TYR A 317 GLY A 331 1 ? 15 
HELX_P HELX_P14 AB5 LEU A 351 ? GLN A 358 ? LEU A 340 GLN A 347 1 ? 8  
HELX_P HELX_P15 AB6 ARG A 361 ? PHE A 379 ? ARG A 350 PHE A 368 1 ? 19 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A ASP 190 O   ? ? ? 1_555 B K   . K  ? ? A ASP 179 A K   401 1_555 ? ? ? ? ? ? ? 2.835 ? ? 
metalc2  metalc ? ? A ASP 190 OD1 ? ? ? 1_555 B K   . K  ? ? A ASP 179 A K   401 1_555 ? ? ? ? ? ? ? 2.588 ? ? 
metalc3  metalc ? ? A ASP 192 O   ? ? ? 1_555 B K   . K  ? ? A ASP 181 A K   401 1_555 ? ? ? ? ? ? ? 2.570 ? ? 
metalc4  metalc ? ? A ASP 192 OD1 ? ? ? 1_555 D ZN  . ZN ? ? A ASP 181 A ZN  403 1_555 ? ? ? ? ? ? ? 1.977 ? ? 
metalc5  metalc ? ? A ASP 192 OD2 ? ? ? 1_555 D ZN  . ZN ? ? A ASP 181 A ZN  403 1_555 ? ? ? ? ? ? ? 2.525 ? ? 
metalc6  metalc ? ? A HIS 194 O   ? ? ? 1_555 B K   . K  ? ? A HIS 183 A K   401 1_555 ? ? ? ? ? ? ? 2.624 ? ? 
metalc7  metalc ? ? A HIS 194 ND1 ? ? ? 1_555 D ZN  . ZN ? ? A HIS 183 A ZN  403 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
metalc8  metalc ? ? A TYR 203 O   ? ? ? 1_555 C K   . K  ? ? A TYR 192 A K   402 1_555 ? ? ? ? ? ? ? 2.583 ? ? 
metalc9  metalc ? ? A ARG 206 O   ? ? ? 1_555 C K   . K  ? ? A ARG 195 A K   402 1_555 ? ? ? ? ? ? ? 2.968 ? ? 
metalc10 metalc ? ? A VAL 209 O   ? ? ? 1_555 C K   . K  ? ? A VAL 198 A K   402 1_555 ? ? ? ? ? ? ? 2.493 ? ? 
metalc11 metalc ? ? A SER 213 OG  ? ? ? 1_555 B K   . K  ? ? A SER 202 A K   401 1_555 ? ? ? ? ? ? ? 2.858 ? ? 
metalc12 metalc ? ? A LEU 214 O   ? ? ? 1_555 B K   . K  ? ? A LEU 203 A K   401 1_555 ? ? ? ? ? ? ? 2.473 ? ? 
metalc13 metalc ? ? A TYR 238 O   ? ? ? 1_555 C K   . K  ? ? A TYR 227 A K   402 1_555 ? ? ? ? ? ? ? 3.059 ? ? 
metalc14 metalc ? ? A ASP 280 OD2 ? ? ? 1_555 D ZN  . ZN ? ? A ASP 269 A ZN  403 1_555 ? ? ? ? ? ? ? 1.995 ? ? 
metalc15 metalc ? ? C K   .   K   ? ? ? 1_555 I HOH . O  ? ? A K   402 A HOH 541 1_555 ? ? ? ? ? ? ? 3.184 ? ? 
metalc16 metalc ? ? C K   .   K   ? ? ? 1_555 I HOH . O  ? ? A K   402 A HOH 584 1_555 ? ? ? ? ? ? ? 2.475 ? ? 
metalc17 metalc ? ? D ZN  .   ZN  ? ? ? 1_555 F TSN . O1 ? ? A ZN  403 A TSN 405 1_555 ? ? ? ? ? ? ? 1.841 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O   ? A ASP 190 ? A ASP 179 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 OD1 ? A ASP 190 ? A ASP 179 ? 1_555 69.6  ? 
2  O   ? A ASP 190 ? A ASP 179 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 O   ? A ASP 192 ? A ASP 181 ? 1_555 98.5  ? 
3  OD1 ? A ASP 190 ? A ASP 179 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 O   ? A ASP 192 ? A ASP 181 ? 1_555 87.6  ? 
4  O   ? A ASP 190 ? A ASP 179 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 O   ? A HIS 194 ? A HIS 183 ? 1_555 168.9 ? 
5  OD1 ? A ASP 190 ? A ASP 179 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 O   ? A HIS 194 ? A HIS 183 ? 1_555 99.3  ? 
6  O   ? A ASP 192 ? A ASP 181 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 O   ? A HIS 194 ? A HIS 183 ? 1_555 81.6  ? 
7  O   ? A ASP 190 ? A ASP 179 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 OG  ? A SER 213 ? A SER 202 ? 1_555 89.7  ? 
8  OD1 ? A ASP 190 ? A ASP 179 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 OG  ? A SER 213 ? A SER 202 ? 1_555 116.3 ? 
9  O   ? A ASP 192 ? A ASP 181 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 OG  ? A SER 213 ? A SER 202 ? 1_555 156.0 ? 
10 O   ? A HIS 194 ? A HIS 183 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 OG  ? A SER 213 ? A SER 202 ? 1_555 94.6  ? 
11 O   ? A ASP 190 ? A ASP 179 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 O   ? A LEU 214 ? A LEU 203 ? 1_555 76.1  ? 
12 OD1 ? A ASP 190 ? A ASP 179 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 O   ? A LEU 214 ? A LEU 203 ? 1_555 138.7 ? 
13 O   ? A ASP 192 ? A ASP 181 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 O   ? A LEU 214 ? A LEU 203 ? 1_555 75.0  ? 
14 O   ? A HIS 194 ? A HIS 183 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 O   ? A LEU 214 ? A LEU 203 ? 1_555 114.5 ? 
15 OG  ? A SER 213 ? A SER 202 ? 1_555 K  ? B K  . ? A K  401 ? 1_555 O   ? A LEU 214 ? A LEU 203 ? 1_555 85.2  ? 
16 OD1 ? A ASP 192 ? A ASP 181 ? 1_555 ZN ? D ZN . ? A ZN 403 ? 1_555 OD2 ? A ASP 192 ? A ASP 181 ? 1_555 58.0  ? 
17 OD1 ? A ASP 192 ? A ASP 181 ? 1_555 ZN ? D ZN . ? A ZN 403 ? 1_555 ND1 ? A HIS 194 ? A HIS 183 ? 1_555 99.2  ? 
18 OD2 ? A ASP 192 ? A ASP 181 ? 1_555 ZN ? D ZN . ? A ZN 403 ? 1_555 ND1 ? A HIS 194 ? A HIS 183 ? 1_555 155.8 ? 
19 OD1 ? A ASP 192 ? A ASP 181 ? 1_555 ZN ? D ZN . ? A ZN 403 ? 1_555 OD2 ? A ASP 280 ? A ASP 269 ? 1_555 106.5 ? 
20 OD2 ? A ASP 192 ? A ASP 181 ? 1_555 ZN ? D ZN . ? A ZN 403 ? 1_555 OD2 ? A ASP 280 ? A ASP 269 ? 1_555 88.7  ? 
21 ND1 ? A HIS 194 ? A HIS 183 ? 1_555 ZN ? D ZN . ? A ZN 403 ? 1_555 OD2 ? A ASP 280 ? A ASP 269 ? 1_555 90.8  ? 
22 OD1 ? A ASP 192 ? A ASP 181 ? 1_555 ZN ? D ZN . ? A ZN 403 ? 1_555 O1  ? F TSN .   ? A TSN 405 ? 1_555 98.7  ? 
23 OD2 ? A ASP 192 ? A ASP 181 ? 1_555 ZN ? D ZN . ? A ZN 403 ? 1_555 O1  ? F TSN .   ? A TSN 405 ? 1_555 91.3  ? 
24 ND1 ? A HIS 194 ? A HIS 183 ? 1_555 ZN ? D ZN . ? A ZN 403 ? 1_555 O1  ? F TSN .   ? A TSN 405 ? 1_555 100.9 ? 
25 OD2 ? A ASP 280 ? A ASP 269 ? 1_555 ZN ? D ZN . ? A ZN 403 ? 1_555 O1  ? F TSN .   ? A TSN 405 ? 1_555 150.1 ? 
26 O   ? A TYR 203 ? A TYR 192 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? A ARG 206 ? A ARG 195 ? 1_555 78.2  ? 
27 O   ? A TYR 203 ? A TYR 192 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? A VAL 209 ? A VAL 198 ? 1_555 131.2 ? 
28 O   ? A ARG 206 ? A ARG 195 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? A VAL 209 ? A VAL 198 ? 1_555 82.7  ? 
29 O   ? A TYR 203 ? A TYR 192 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? A TYR 238 ? A TYR 227 ? 1_555 148.1 ? 
30 O   ? A ARG 206 ? A ARG 195 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? A TYR 238 ? A TYR 227 ? 1_555 114.4 ? 
31 O   ? A VAL 209 ? A VAL 198 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? A TYR 238 ? A TYR 227 ? 1_555 80.6  ? 
32 O   ? A TYR 203 ? A TYR 192 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? I HOH .   ? A HOH 541 ? 1_555 65.8  ? 
33 O   ? A ARG 206 ? A ARG 195 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? I HOH .   ? A HOH 541 ? 1_555 137.6 ? 
34 O   ? A VAL 209 ? A VAL 198 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? I HOH .   ? A HOH 541 ? 1_555 138.1 ? 
35 O   ? A TYR 238 ? A TYR 227 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? I HOH .   ? A HOH 541 ? 1_555 88.6  ? 
36 O   ? A TYR 203 ? A TYR 192 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? I HOH .   ? A HOH 584 ? 1_555 77.3  ? 
37 O   ? A ARG 206 ? A ARG 195 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? I HOH .   ? A HOH 584 ? 1_555 79.5  ? 
38 O   ? A VAL 209 ? A VAL 198 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? I HOH .   ? A HOH 584 ? 1_555 141.9 ? 
39 O   ? A TYR 238 ? A TYR 227 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? I HOH .   ? A HOH 584 ? 1_555 76.6  ? 
40 O   ? I HOH .   ? A HOH 541 ? 1_555 K  ? C K  . ? A K  402 ? 1_555 O   ? I HOH .   ? A HOH 584 ? 1_555 71.6  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ARG 150 A . ? ARG 139 A PRO 151 A ? PRO 140 A 1 4.69  
2 PHE 220 A . ? PHE 209 A PRO 221 A ? PRO 210 A 1 -7.48 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA1 7 8 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 74  ? ARG A 76  ? ALA A 63  ARG A 65  
AA1 2 THR A 16  ? PHE A 19  ? THR A 5   PHE A 8   
AA1 3 ASN A 144 ? SER A 147 ? ASN A 133 SER A 136 
AA1 4 LEU A 316 ? HIS A 320 ? LEU A 305 HIS A 309 
AA1 5 ILE A 273 ? CYS A 277 ? ILE A 262 CYS A 266 
AA1 6 VAL A 186 ? ASP A 190 ? VAL A 175 ASP A 179 
AA1 7 VAL A 209 ? GLN A 216 ? VAL A 198 GLN A 205 
AA1 8 ASN A 239 ? LEU A 244 ? ASN A 228 LEU A 233 
AA2 1 HIS A 32  ? ALA A 33  ? HIS A 21  ALA A 22  
AA2 2 LEU A 36  ? PRO A 37  ? LEU A 25  PRO A 26  
AA3 1 GLY A 107 ? MET A 108 ? GLY A 96  MET A 97  
AA3 2 PRO A 114 ? LEU A 115 ? PRO A 103 LEU A 104 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 74  ? O ALA A 63  N THR A 16  ? N THR A 5   
AA1 2 3 N PHE A 19  ? N PHE A 8   O TYR A 146 ? O TYR A 135 
AA1 3 4 N ALA A 145 ? N ALA A 134 O MET A 318 ? O MET A 307 
AA1 4 5 O VAL A 317 ? O VAL A 306 N ILE A 275 ? N ILE A 264 
AA1 5 6 O ALA A 276 ? O ALA A 265 N ILE A 189 ? N ILE A 178 
AA1 6 7 N ILE A 188 ? N ILE A 177 O LEU A 210 ? O LEU A 199 
AA1 7 8 N SER A 213 ? N SER A 202 O ILE A 242 ? O ILE A 231 
AA2 1 2 N ALA A 33  ? N ALA A 22  O LEU A 36  ? O LEU A 25  
AA3 1 2 N GLY A 107 ? N GLY A 96  O LEU A 115 ? O LEU A 104 
# 
_pdbx_entry_details.entry_id                   9GN7 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 HD1  A HIS 183 ? ? ZN A ZN  403 ? ? 1.16 
2 1 HE21 A GLN 189 ? ? HH A TYR 213 ? ? 1.27 
3 1 HH21 A ARG 256 ? ? O  A HOH 503 ? ? 1.58 
4 1 O    A HOH 586 ? ? O  A HOH 610 ? ? 1.59 
5 1 O    A HOH 555 ? ? O  A HOH 611 ? ? 2.11 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 NE A ARG 86  ? ? CZ A ARG 86  ? ? NH1 A ARG 86  ? ? 124.82 120.30 4.52  0.50 N 
2 1 NE A ARG 139 ? ? CZ A ARG 139 ? ? NH1 A ARG 139 ? ? 123.39 120.30 3.09  0.50 N 
3 1 NE A ARG 219 ? ? CZ A ARG 219 ? ? NH2 A ARG 219 ? ? 117.22 120.30 -3.08 0.50 N 
4 1 NE A ARG 287 ? ? CZ A ARG 287 ? ? NH1 A ARG 287 ? ? 116.92 120.30 -3.38 0.50 N 
5 1 NE A ARG 358 ? ? CZ A ARG 358 ? ? NH1 A ARG 358 ? ? 124.29 120.30 3.99  0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 THR A 18  ? ? -143.45 16.02   
2 1 VAL A 23  ? ? 62.80   -102.76 
3 1 SER A 66  ? ? -108.25 -160.10 
4 1 LEU A 98  ? ? -106.51 78.45   
5 1 GLU A 101 ? ? 36.03   72.28   
6 1 ALA A 102 ? ? -164.56 78.70   
7 1 ALA A 214 ? ? -103.19 -66.11  
8 1 CYS A 301 ? ? -143.79 33.74   
9 1 GLU A 310 ? ? -116.96 -104.20 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 219 ? ? 0.085 'SIDE CHAIN' 
2 1 ARG A 256 ? ? 0.133 'SIDE CHAIN' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1  x,y,z               
2  z,x,y               
3  y,z,x               
4  -y,-z,x             
5  z,-x,-y             
6  -y,z,-x             
7  -z,-x,y             
8  -z,x,-y             
9  y,-z,-x             
10 x,-y,-z             
11 -x,y,-z             
12 -x,-y,z             
13 x+1/2,y+1/2,z+1/2   
14 z+1/2,x+1/2,y+1/2   
15 y+1/2,z+1/2,x+1/2   
16 -y+1/2,-z+1/2,x+1/2 
17 z+1/2,-x+1/2,-y+1/2 
18 -y+1/2,z+1/2,-x+1/2 
19 -z+1/2,-x+1/2,y+1/2 
20 -z+1/2,x+1/2,-y+1/2 
21 y+1/2,-z+1/2,-x+1/2 
22 x+1/2,-y+1/2,-z+1/2 
23 -x+1/2,y+1/2,-z+1/2 
24 -x+1/2,-y+1/2,z+1/2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET -10 ? A MET 1  
2  1 Y 1 A ALA -9  ? A ALA 2  
3  1 Y 1 A HIS -8  ? A HIS 3  
4  1 Y 1 A HIS -7  ? A HIS 4  
5  1 Y 1 A HIS -6  ? A HIS 5  
6  1 Y 1 A HIS -5  ? A HIS 6  
7  1 Y 1 A HIS -4  ? A HIS 7  
8  1 Y 1 A HIS -3  ? A HIS 8  
9  1 Y 1 A VAL -2  ? A VAL 9  
10 1 Y 1 A GLY -1  ? A GLY 10 
11 1 Y 1 A THR 0   ? A THR 11 
12 1 Y 1 A MET 1   ? A MET 12 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
GOL C1   C  N N 137 
GOL O1   O  N N 138 
GOL C2   C  N N 139 
GOL O2   O  N N 140 
GOL C3   C  N N 141 
GOL O3   O  N N 142 
GOL H11  H  N N 143 
GOL H12  H  N N 144 
GOL HO1  H  N N 145 
GOL H2   H  N N 146 
GOL HO2  H  N N 147 
GOL H31  H  N N 148 
GOL H32  H  N N 149 
GOL HO3  H  N N 150 
HIS N    N  N N 151 
HIS CA   C  N S 152 
HIS C    C  N N 153 
HIS O    O  N N 154 
HIS CB   C  N N 155 
HIS CG   C  Y N 156 
HIS ND1  N  Y N 157 
HIS CD2  C  Y N 158 
HIS CE1  C  Y N 159 
HIS NE2  N  Y N 160 
HIS OXT  O  N N 161 
HIS H    H  N N 162 
HIS H2   H  N N 163 
HIS HA   H  N N 164 
HIS HB2  H  N N 165 
HIS HB3  H  N N 166 
HIS HD1  H  N N 167 
HIS HD2  H  N N 168 
HIS HE1  H  N N 169 
HIS HE2  H  N N 170 
HIS HXT  H  N N 171 
HOH O    O  N N 172 
HOH H1   H  N N 173 
HOH H2   H  N N 174 
ILE N    N  N N 175 
ILE CA   C  N S 176 
ILE C    C  N N 177 
ILE O    O  N N 178 
ILE CB   C  N S 179 
ILE CG1  C  N N 180 
ILE CG2  C  N N 181 
ILE CD1  C  N N 182 
ILE OXT  O  N N 183 
ILE H    H  N N 184 
ILE H2   H  N N 185 
ILE HA   H  N N 186 
ILE HB   H  N N 187 
ILE HG12 H  N N 188 
ILE HG13 H  N N 189 
ILE HG21 H  N N 190 
ILE HG22 H  N N 191 
ILE HG23 H  N N 192 
ILE HD11 H  N N 193 
ILE HD12 H  N N 194 
ILE HD13 H  N N 195 
ILE HXT  H  N N 196 
K   K    K  N N 197 
LEU N    N  N N 198 
LEU CA   C  N S 199 
LEU C    C  N N 200 
LEU O    O  N N 201 
LEU CB   C  N N 202 
LEU CG   C  N N 203 
LEU CD1  C  N N 204 
LEU CD2  C  N N 205 
LEU OXT  O  N N 206 
LEU H    H  N N 207 
LEU H2   H  N N 208 
LEU HA   H  N N 209 
LEU HB2  H  N N 210 
LEU HB3  H  N N 211 
LEU HG   H  N N 212 
LEU HD11 H  N N 213 
LEU HD12 H  N N 214 
LEU HD13 H  N N 215 
LEU HD21 H  N N 216 
LEU HD22 H  N N 217 
LEU HD23 H  N N 218 
LEU HXT  H  N N 219 
LYS N    N  N N 220 
LYS CA   C  N S 221 
LYS C    C  N N 222 
LYS O    O  N N 223 
LYS CB   C  N N 224 
LYS CG   C  N N 225 
LYS CD   C  N N 226 
LYS CE   C  N N 227 
LYS NZ   N  N N 228 
LYS OXT  O  N N 229 
LYS H    H  N N 230 
LYS H2   H  N N 231 
LYS HA   H  N N 232 
LYS HB2  H  N N 233 
LYS HB3  H  N N 234 
LYS HG2  H  N N 235 
LYS HG3  H  N N 236 
LYS HD2  H  N N 237 
LYS HD3  H  N N 238 
LYS HE2  H  N N 239 
LYS HE3  H  N N 240 
LYS HZ1  H  N N 241 
LYS HZ2  H  N N 242 
LYS HZ3  H  N N 243 
LYS HXT  H  N N 244 
MET N    N  N N 245 
MET CA   C  N S 246 
MET C    C  N N 247 
MET O    O  N N 248 
MET CB   C  N N 249 
MET CG   C  N N 250 
MET SD   S  N N 251 
MET CE   C  N N 252 
MET OXT  O  N N 253 
MET H    H  N N 254 
MET H2   H  N N 255 
MET HA   H  N N 256 
MET HB2  H  N N 257 
MET HB3  H  N N 258 
MET HG2  H  N N 259 
MET HG3  H  N N 260 
MET HE1  H  N N 261 
MET HE2  H  N N 262 
MET HE3  H  N N 263 
MET HXT  H  N N 264 
PHE N    N  N N 265 
PHE CA   C  N S 266 
PHE C    C  N N 267 
PHE O    O  N N 268 
PHE CB   C  N N 269 
PHE CG   C  Y N 270 
PHE CD1  C  Y N 271 
PHE CD2  C  Y N 272 
PHE CE1  C  Y N 273 
PHE CE2  C  Y N 274 
PHE CZ   C  Y N 275 
PHE OXT  O  N N 276 
PHE H    H  N N 277 
PHE H2   H  N N 278 
PHE HA   H  N N 279 
PHE HB2  H  N N 280 
PHE HB3  H  N N 281 
PHE HD1  H  N N 282 
PHE HD2  H  N N 283 
PHE HE1  H  N N 284 
PHE HE2  H  N N 285 
PHE HZ   H  N N 286 
PHE HXT  H  N N 287 
PO4 P    P  N N 288 
PO4 O1   O  N N 289 
PO4 O2   O  N N 290 
PO4 O3   O  N N 291 
PO4 O4   O  N N 292 
PRO N    N  N N 293 
PRO CA   C  N S 294 
PRO C    C  N N 295 
PRO O    O  N N 296 
PRO CB   C  N N 297 
PRO CG   C  N N 298 
PRO CD   C  N N 299 
PRO OXT  O  N N 300 
PRO H    H  N N 301 
PRO HA   H  N N 302 
PRO HB2  H  N N 303 
PRO HB3  H  N N 304 
PRO HG2  H  N N 305 
PRO HG3  H  N N 306 
PRO HD2  H  N N 307 
PRO HD3  H  N N 308 
PRO HXT  H  N N 309 
SER N    N  N N 310 
SER CA   C  N S 311 
SER C    C  N N 312 
SER O    O  N N 313 
SER CB   C  N N 314 
SER OG   O  N N 315 
SER OXT  O  N N 316 
SER H    H  N N 317 
SER H2   H  N N 318 
SER HA   H  N N 319 
SER HB2  H  N N 320 
SER HB3  H  N N 321 
SER HG   H  N N 322 
SER HXT  H  N N 323 
THR N    N  N N 324 
THR CA   C  N S 325 
THR C    C  N N 326 
THR O    O  N N 327 
THR CB   C  N R 328 
THR OG1  O  N N 329 
THR CG2  C  N N 330 
THR OXT  O  N N 331 
THR H    H  N N 332 
THR H2   H  N N 333 
THR HA   H  N N 334 
THR HB   H  N N 335 
THR HG1  H  N N 336 
THR HG21 H  N N 337 
THR HG22 H  N N 338 
THR HG23 H  N N 339 
THR HXT  H  N N 340 
TRP N    N  N N 341 
TRP CA   C  N S 342 
TRP C    C  N N 343 
TRP O    O  N N 344 
TRP CB   C  N N 345 
TRP CG   C  Y N 346 
TRP CD1  C  Y N 347 
TRP CD2  C  Y N 348 
TRP NE1  N  Y N 349 
TRP CE2  C  Y N 350 
TRP CE3  C  Y N 351 
TRP CZ2  C  Y N 352 
TRP CZ3  C  Y N 353 
TRP CH2  C  Y N 354 
TRP OXT  O  N N 355 
TRP H    H  N N 356 
TRP H2   H  N N 357 
TRP HA   H  N N 358 
TRP HB2  H  N N 359 
TRP HB3  H  N N 360 
TRP HD1  H  N N 361 
TRP HE1  H  N N 362 
TRP HE3  H  N N 363 
TRP HZ2  H  N N 364 
TRP HZ3  H  N N 365 
TRP HH2  H  N N 366 
TRP HXT  H  N N 367 
TSN O1   O  N N 368 
TSN O2   O  N N 369 
TSN O3   O  N N 370 
TSN N1   N  N N 371 
TSN N2   N  N N 372 
TSN C1   C  Y N 373 
TSN C2   C  Y N 374 
TSN C3   C  Y N 375 
TSN C4   C  Y N 376 
TSN C5   C  Y N 377 
TSN C6   C  Y N 378 
TSN C7   C  N N 379 
TSN C8   C  N R 380 
TSN C9   C  N N 381 
TSN C10  C  N N 382 
TSN C11  C  N N 383 
TSN C12  C  N N 384 
TSN C13  C  N N 385 
TSN C14  C  N N 386 
TSN C15  C  N N 387 
TSN C17  C  N N 388 
TSN C16  C  N N 389 
TSN HO1  H  N N 390 
TSN HN1  H  N N 391 
TSN H21  H  N N 392 
TSN H31  H  N N 393 
TSN H51  H  N N 394 
TSN H61  H  N N 395 
TSN H8   H  N N 396 
TSN H9   H  N N 397 
TSN H111 H  N N 398 
TSN H121 H  N N 399 
TSN H141 H  N N 400 
TSN H142 H  N N 401 
TSN H143 H  N N 402 
TSN H151 H  N N 403 
TSN H152 H  N N 404 
TSN H153 H  N N 405 
TSN H171 H  N N 406 
TSN H172 H  N N 407 
TSN H173 H  N N 408 
TSN H161 H  N N 409 
TSN H162 H  N N 410 
TSN H163 H  N N 411 
TYR N    N  N N 412 
TYR CA   C  N S 413 
TYR C    C  N N 414 
TYR O    O  N N 415 
TYR CB   C  N N 416 
TYR CG   C  Y N 417 
TYR CD1  C  Y N 418 
TYR CD2  C  Y N 419 
TYR CE1  C  Y N 420 
TYR CE2  C  Y N 421 
TYR CZ   C  Y N 422 
TYR OH   O  N N 423 
TYR OXT  O  N N 424 
TYR H    H  N N 425 
TYR H2   H  N N 426 
TYR HA   H  N N 427 
TYR HB2  H  N N 428 
TYR HB3  H  N N 429 
TYR HD1  H  N N 430 
TYR HD2  H  N N 431 
TYR HE1  H  N N 432 
TYR HE2  H  N N 433 
TYR HH   H  N N 434 
TYR HXT  H  N N 435 
VAL N    N  N N 436 
VAL CA   C  N S 437 
VAL C    C  N N 438 
VAL O    O  N N 439 
VAL CB   C  N N 440 
VAL CG1  C  N N 441 
VAL CG2  C  N N 442 
VAL OXT  O  N N 443 
VAL H    H  N N 444 
VAL H2   H  N N 445 
VAL HA   H  N N 446 
VAL HB   H  N N 447 
VAL HG11 H  N N 448 
VAL HG12 H  N N 449 
VAL HG13 H  N N 450 
VAL HG21 H  N N 451 
VAL HG22 H  N N 452 
VAL HG23 H  N N 453 
VAL HXT  H  N N 454 
ZN  ZN   ZN N N 455 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
GOL C1  O1   sing N N 129 
GOL C1  C2   sing N N 130 
GOL C1  H11  sing N N 131 
GOL C1  H12  sing N N 132 
GOL O1  HO1  sing N N 133 
GOL C2  O2   sing N N 134 
GOL C2  C3   sing N N 135 
GOL C2  H2   sing N N 136 
GOL O2  HO2  sing N N 137 
GOL C3  O3   sing N N 138 
GOL C3  H31  sing N N 139 
GOL C3  H32  sing N N 140 
GOL O3  HO3  sing N N 141 
HIS N   CA   sing N N 142 
HIS N   H    sing N N 143 
HIS N   H2   sing N N 144 
HIS CA  C    sing N N 145 
HIS CA  CB   sing N N 146 
HIS CA  HA   sing N N 147 
HIS C   O    doub N N 148 
HIS C   OXT  sing N N 149 
HIS CB  CG   sing N N 150 
HIS CB  HB2  sing N N 151 
HIS CB  HB3  sing N N 152 
HIS CG  ND1  sing Y N 153 
HIS CG  CD2  doub Y N 154 
HIS ND1 CE1  doub Y N 155 
HIS ND1 HD1  sing N N 156 
HIS CD2 NE2  sing Y N 157 
HIS CD2 HD2  sing N N 158 
HIS CE1 NE2  sing Y N 159 
HIS CE1 HE1  sing N N 160 
HIS NE2 HE2  sing N N 161 
HIS OXT HXT  sing N N 162 
HOH O   H1   sing N N 163 
HOH O   H2   sing N N 164 
ILE N   CA   sing N N 165 
ILE N   H    sing N N 166 
ILE N   H2   sing N N 167 
ILE CA  C    sing N N 168 
ILE CA  CB   sing N N 169 
ILE CA  HA   sing N N 170 
ILE C   O    doub N N 171 
ILE C   OXT  sing N N 172 
ILE CB  CG1  sing N N 173 
ILE CB  CG2  sing N N 174 
ILE CB  HB   sing N N 175 
ILE CG1 CD1  sing N N 176 
ILE CG1 HG12 sing N N 177 
ILE CG1 HG13 sing N N 178 
ILE CG2 HG21 sing N N 179 
ILE CG2 HG22 sing N N 180 
ILE CG2 HG23 sing N N 181 
ILE CD1 HD11 sing N N 182 
ILE CD1 HD12 sing N N 183 
ILE CD1 HD13 sing N N 184 
ILE OXT HXT  sing N N 185 
LEU N   CA   sing N N 186 
LEU N   H    sing N N 187 
LEU N   H2   sing N N 188 
LEU CA  C    sing N N 189 
LEU CA  CB   sing N N 190 
LEU CA  HA   sing N N 191 
LEU C   O    doub N N 192 
LEU C   OXT  sing N N 193 
LEU CB  CG   sing N N 194 
LEU CB  HB2  sing N N 195 
LEU CB  HB3  sing N N 196 
LEU CG  CD1  sing N N 197 
LEU CG  CD2  sing N N 198 
LEU CG  HG   sing N N 199 
LEU CD1 HD11 sing N N 200 
LEU CD1 HD12 sing N N 201 
LEU CD1 HD13 sing N N 202 
LEU CD2 HD21 sing N N 203 
LEU CD2 HD22 sing N N 204 
LEU CD2 HD23 sing N N 205 
LEU OXT HXT  sing N N 206 
LYS N   CA   sing N N 207 
LYS N   H    sing N N 208 
LYS N   H2   sing N N 209 
LYS CA  C    sing N N 210 
LYS CA  CB   sing N N 211 
LYS CA  HA   sing N N 212 
LYS C   O    doub N N 213 
LYS C   OXT  sing N N 214 
LYS CB  CG   sing N N 215 
LYS CB  HB2  sing N N 216 
LYS CB  HB3  sing N N 217 
LYS CG  CD   sing N N 218 
LYS CG  HG2  sing N N 219 
LYS CG  HG3  sing N N 220 
LYS CD  CE   sing N N 221 
LYS CD  HD2  sing N N 222 
LYS CD  HD3  sing N N 223 
LYS CE  NZ   sing N N 224 
LYS CE  HE2  sing N N 225 
LYS CE  HE3  sing N N 226 
LYS NZ  HZ1  sing N N 227 
LYS NZ  HZ2  sing N N 228 
LYS NZ  HZ3  sing N N 229 
LYS OXT HXT  sing N N 230 
MET N   CA   sing N N 231 
MET N   H    sing N N 232 
MET N   H2   sing N N 233 
MET CA  C    sing N N 234 
MET CA  CB   sing N N 235 
MET CA  HA   sing N N 236 
MET C   O    doub N N 237 
MET C   OXT  sing N N 238 
MET CB  CG   sing N N 239 
MET CB  HB2  sing N N 240 
MET CB  HB3  sing N N 241 
MET CG  SD   sing N N 242 
MET CG  HG2  sing N N 243 
MET CG  HG3  sing N N 244 
MET SD  CE   sing N N 245 
MET CE  HE1  sing N N 246 
MET CE  HE2  sing N N 247 
MET CE  HE3  sing N N 248 
MET OXT HXT  sing N N 249 
PHE N   CA   sing N N 250 
PHE N   H    sing N N 251 
PHE N   H2   sing N N 252 
PHE CA  C    sing N N 253 
PHE CA  CB   sing N N 254 
PHE CA  HA   sing N N 255 
PHE C   O    doub N N 256 
PHE C   OXT  sing N N 257 
PHE CB  CG   sing N N 258 
PHE CB  HB2  sing N N 259 
PHE CB  HB3  sing N N 260 
PHE CG  CD1  doub Y N 261 
PHE CG  CD2  sing Y N 262 
PHE CD1 CE1  sing Y N 263 
PHE CD1 HD1  sing N N 264 
PHE CD2 CE2  doub Y N 265 
PHE CD2 HD2  sing N N 266 
PHE CE1 CZ   doub Y N 267 
PHE CE1 HE1  sing N N 268 
PHE CE2 CZ   sing Y N 269 
PHE CE2 HE2  sing N N 270 
PHE CZ  HZ   sing N N 271 
PHE OXT HXT  sing N N 272 
PO4 P   O1   doub N N 273 
PO4 P   O2   sing N N 274 
PO4 P   O3   sing N N 275 
PO4 P   O4   sing N N 276 
PRO N   CA   sing N N 277 
PRO N   CD   sing N N 278 
PRO N   H    sing N N 279 
PRO CA  C    sing N N 280 
PRO CA  CB   sing N N 281 
PRO CA  HA   sing N N 282 
PRO C   O    doub N N 283 
PRO C   OXT  sing N N 284 
PRO CB  CG   sing N N 285 
PRO CB  HB2  sing N N 286 
PRO CB  HB3  sing N N 287 
PRO CG  CD   sing N N 288 
PRO CG  HG2  sing N N 289 
PRO CG  HG3  sing N N 290 
PRO CD  HD2  sing N N 291 
PRO CD  HD3  sing N N 292 
PRO OXT HXT  sing N N 293 
SER N   CA   sing N N 294 
SER N   H    sing N N 295 
SER N   H2   sing N N 296 
SER CA  C    sing N N 297 
SER CA  CB   sing N N 298 
SER CA  HA   sing N N 299 
SER C   O    doub N N 300 
SER C   OXT  sing N N 301 
SER CB  OG   sing N N 302 
SER CB  HB2  sing N N 303 
SER CB  HB3  sing N N 304 
SER OG  HG   sing N N 305 
SER OXT HXT  sing N N 306 
THR N   CA   sing N N 307 
THR N   H    sing N N 308 
THR N   H2   sing N N 309 
THR CA  C    sing N N 310 
THR CA  CB   sing N N 311 
THR CA  HA   sing N N 312 
THR C   O    doub N N 313 
THR C   OXT  sing N N 314 
THR CB  OG1  sing N N 315 
THR CB  CG2  sing N N 316 
THR CB  HB   sing N N 317 
THR OG1 HG1  sing N N 318 
THR CG2 HG21 sing N N 319 
THR CG2 HG22 sing N N 320 
THR CG2 HG23 sing N N 321 
THR OXT HXT  sing N N 322 
TRP N   CA   sing N N 323 
TRP N   H    sing N N 324 
TRP N   H2   sing N N 325 
TRP CA  C    sing N N 326 
TRP CA  CB   sing N N 327 
TRP CA  HA   sing N N 328 
TRP C   O    doub N N 329 
TRP C   OXT  sing N N 330 
TRP CB  CG   sing N N 331 
TRP CB  HB2  sing N N 332 
TRP CB  HB3  sing N N 333 
TRP CG  CD1  doub Y N 334 
TRP CG  CD2  sing Y N 335 
TRP CD1 NE1  sing Y N 336 
TRP CD1 HD1  sing N N 337 
TRP CD2 CE2  doub Y N 338 
TRP CD2 CE3  sing Y N 339 
TRP NE1 CE2  sing Y N 340 
TRP NE1 HE1  sing N N 341 
TRP CE2 CZ2  sing Y N 342 
TRP CE3 CZ3  doub Y N 343 
TRP CE3 HE3  sing N N 344 
TRP CZ2 CH2  doub Y N 345 
TRP CZ2 HZ2  sing N N 346 
TRP CZ3 CH2  sing Y N 347 
TRP CZ3 HZ3  sing N N 348 
TRP CH2 HH2  sing N N 349 
TRP OXT HXT  sing N N 350 
TSN O1  N1   sing N N 351 
TSN O1  HO1  sing N N 352 
TSN O2  C13  doub N N 353 
TSN O3  C7   doub N N 354 
TSN N1  C13  sing N N 355 
TSN N1  HN1  sing N N 356 
TSN N2  C4   sing N N 357 
TSN N2  C17  sing N N 358 
TSN N2  C16  sing N N 359 
TSN C1  C2   doub Y N 360 
TSN C1  C6   sing Y N 361 
TSN C1  C7   sing N N 362 
TSN C2  C3   sing Y N 363 
TSN C2  H21  sing N N 364 
TSN C3  C4   doub Y N 365 
TSN C3  H31  sing N N 366 
TSN C4  C5   sing Y N 367 
TSN C5  C6   doub Y N 368 
TSN C5  H51  sing N N 369 
TSN C6  H61  sing N N 370 
TSN C7  C8   sing N N 371 
TSN C8  C9   sing N N 372 
TSN C8  C14  sing N N 373 
TSN C8  H8   sing N N 374 
TSN C9  C10  doub N E 375 
TSN C9  H9   sing N N 376 
TSN C10 C11  sing N N 377 
TSN C10 C15  sing N N 378 
TSN C11 C12  doub N E 379 
TSN C11 H111 sing N N 380 
TSN C12 C13  sing N N 381 
TSN C12 H121 sing N N 382 
TSN C14 H141 sing N N 383 
TSN C14 H142 sing N N 384 
TSN C14 H143 sing N N 385 
TSN C15 H151 sing N N 386 
TSN C15 H152 sing N N 387 
TSN C15 H153 sing N N 388 
TSN C17 H171 sing N N 389 
TSN C17 H172 sing N N 390 
TSN C17 H173 sing N N 391 
TSN C16 H161 sing N N 392 
TSN C16 H162 sing N N 393 
TSN C16 H163 sing N N 394 
TYR N   CA   sing N N 395 
TYR N   H    sing N N 396 
TYR N   H2   sing N N 397 
TYR CA  C    sing N N 398 
TYR CA  CB   sing N N 399 
TYR CA  HA   sing N N 400 
TYR C   O    doub N N 401 
TYR C   OXT  sing N N 402 
TYR CB  CG   sing N N 403 
TYR CB  HB2  sing N N 404 
TYR CB  HB3  sing N N 405 
TYR CG  CD1  doub Y N 406 
TYR CG  CD2  sing Y N 407 
TYR CD1 CE1  sing Y N 408 
TYR CD1 HD1  sing N N 409 
TYR CD2 CE2  doub Y N 410 
TYR CD2 HD2  sing N N 411 
TYR CE1 CZ   doub Y N 412 
TYR CE1 HE1  sing N N 413 
TYR CE2 CZ   sing Y N 414 
TYR CE2 HE2  sing N N 415 
TYR CZ  OH   sing N N 416 
TYR OH  HH   sing N N 417 
TYR OXT HXT  sing N N 418 
VAL N   CA   sing N N 419 
VAL N   H    sing N N 420 
VAL N   H2   sing N N 421 
VAL CA  C    sing N N 422 
VAL CA  CB   sing N N 423 
VAL CA  HA   sing N N 424 
VAL C   O    doub N N 425 
VAL C   OXT  sing N N 426 
VAL CB  CG1  sing N N 427 
VAL CB  CG2  sing N N 428 
VAL CB  HB   sing N N 429 
VAL CG1 HG11 sing N N 430 
VAL CG1 HG12 sing N N 431 
VAL CG1 HG13 sing N N 432 
VAL CG2 HG21 sing N N 433 
VAL CG2 HG22 sing N N 434 
VAL CG2 HG23 sing N N 435 
VAL OXT HXT  sing N N 436 
# 
_pdbx_audit_support.funding_organization   'German Research Foundation (DFG)' 
_pdbx_audit_support.country                Germany 
_pdbx_audit_support.grant_number           LA2984/6-1 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5G0X 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'I 2 3' 
_space_group.name_Hall        'I 2 2 3' 
_space_group.IT_number        197 
_space_group.crystal_system   cubic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9GN7 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006823 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006823 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006823 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345  0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
K  ? ? 16.37977 2.54835 ? ? 4.54127  84.28225 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P  ? ? 9.51135  5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN ? ? 24.64596 5.25405 ? ? 2.14387  29.76375 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . LYS A 1 13  ? -19.91  -6.895  38.732 1   84.17   ? 2   LYS A N    1 
ATOM   2    C  CA   . LYS A 1 13  ? -18.595 -6.212  38.582 1   95.821  ? 2   LYS A CA   1 
ATOM   3    C  C    . LYS A 1 13  ? -18.799 -4.836  37.915 1   94.788  ? 2   LYS A C    1 
ATOM   4    O  O    . LYS A 1 13  ? -18.85  -4.687  36.682 1   80.386  ? 2   LYS A O    1 
ATOM   5    C  CB   . LYS A 1 13  ? -17.542 -7.119  37.915 1   109.672 ? 2   LYS A CB   1 
ATOM   6    C  CG   . LYS A 1 13  ? -17.049 -8.341  38.724 1   121.126 ? 2   LYS A CG   1 
ATOM   7    C  CD   . LYS A 1 13  ? -16.117 -9.352  38.027 1   120.13  ? 2   LYS A CD   1 
ATOM   8    C  CE   . LYS A 1 13  ? -16.371 -10.812 38.383 1   116.96  ? 2   LYS A CE   1 
ATOM   9    N  NZ   . LYS A 1 13  ? -16.439 -11.08  39.83  1   115.564 ? 2   LYS A NZ   1 
ATOM   10   H  H    . LYS A 1 13  ? -19.82  -7.635  39.24  1   87.849  ? 2   LYS A H    1 
ATOM   11   H  HA   . LYS A 1 13  ? -18.252 -6.045  39.496 1   95.579  ? 2   LYS A HA   1 
ATOM   12   H  HB2  . LYS A 1 13  ? -17.915 -7.447  37.069 1   108.778 ? 2   LYS A HB2  1 
ATOM   13   H  HB3  . LYS A 1 13  ? -16.761 -6.568  37.694 1   108.778 ? 2   LYS A HB3  1 
ATOM   14   H  HG2  . LYS A 1 13  ? -16.589 -8.002  39.523 1   118.146 ? 2   LYS A HG2  1 
ATOM   15   H  HG3  . LYS A 1 13  ? -17.843 -8.825  39.042 1   117.928 ? 2   LYS A HG3  1 
ATOM   16   H  HD2  . LYS A 1 13  ? -16.213 -9.245  37.056 1   119.623 ? 2   LYS A HD2  1 
ATOM   17   H  HD3  . LYS A 1 13  ? -15.189 -9.129  38.257 1   119.624 ? 2   LYS A HD3  1 
ATOM   18   H  HE2  . LYS A 1 13  ? -17.219 -11.085 37.986 1   117.338 ? 2   LYS A HE2  1 
ATOM   19   H  HE3  . LYS A 1 13  ? -15.672 -11.368 37.996 1   117.336 ? 2   LYS A HE3  1 
ATOM   20   H  HZ1  . LYS A 1 13  ? -17.045 -10.536 40.231 1   116.04  ? 2   LYS A HZ1  1 
ATOM   21   H  HZ2  . LYS A 1 13  ? -15.626 -10.945 40.207 1   116.009 ? 2   LYS A HZ2  1 
ATOM   22   H  HZ3  . LYS A 1 13  ? -16.69  -11.942 39.968 1   116.009 ? 2   LYS A HZ3  1 
ATOM   23   N  N    . ARG A 1 14  ? -18.891 -3.832  38.81  1   91.731  ? 3   ARG A N    1 
ATOM   24   C  CA   . ARG A 1 14  ? -18.789 -2.397  38.55  1   73.568  ? 3   ARG A CA   1 
ATOM   25   C  C    . ARG A 1 14  ? -17.306 -2.005  38.52  1   66.096  ? 3   ARG A C    1 
ATOM   26   O  O    . ARG A 1 14  ? -16.459 -2.78   38.941 1   59.625  ? 3   ARG A O    1 
ATOM   27   C  CB   . ARG A 1 14  ? -19.567 -1.742  39.704 1   63.024  ? 3   ARG A CB   1 
ATOM   28   C  CG   . ARG A 1 14  ? -20.852 -2.507  40.019 1   69.626  ? 3   ARG A CG   1 
ATOM   29   C  CD   . ARG A 1 14  ? -21.97  -1.758  40.683 1   61.818  ? 3   ARG A CD   1 
ATOM   30   N  NE   . ARG A 1 14  ? -23.122 -2.609  41.026 1   72.108  ? 3   ARG A NE   1 
ATOM   31   C  CZ   . ARG A 1 14  ? -23.27  -3.411  42.089 1   86.115  ? 3   ARG A CZ   1 
ATOM   32   N  NH1  . ARG A 1 14  ? -22.375 -3.461  43.053 1   76.058  ? 3   ARG A NH1  1 
ATOM   33   N  NH2  . ARG A 1 14  ? -24.358 -4.147  42.231 1   89.978  ? 3   ARG A NH2  1 
ATOM   34   H  H    . ARG A 1 14  ? -18.999 -4.084  39.682 1   87.42   ? 3   ARG A H    1 
ATOM   35   H  HA   . ARG A 1 14  ? -19.21  -2.194  37.676 1   73.322  ? 3   ARG A HA   1 
ATOM   36   H  HB2  . ARG A 1 14  ? -19.001 -1.717  40.505 1   66.747  ? 3   ARG A HB2  1 
ATOM   37   H  HB3  . ARG A 1 14  ? -19.793 -0.819  39.461 1   66.751  ? 3   ARG A HB3  1 
ATOM   38   H  HG2  . ARG A 1 14  ? -21.198 -2.887  39.182 1   66.432  ? 3   ARG A HG2  1 
ATOM   39   H  HG3  . ARG A 1 14  ? -20.622 -3.269  40.594 1   66.523  ? 3   ARG A HG3  1 
ATOM   40   H  HD2  . ARG A 1 14  ? -21.628 -1.338  41.498 1   65.706  ? 3   ARG A HD2  1 
ATOM   41   H  HD3  . ARG A 1 14  ? -22.268 -1.044  40.084 1   65.834  ? 3   ARG A HD3  1 
ATOM   42   H  HE   . ARG A 1 14  ? -23.794 -2.59   40.472 1   72.781  ? 3   ARG A HE   1 
ATOM   43   H  HH11 . ARG A 1 14  ? -22.066 -2.71   43.404 1   78.8    ? 3   ARG A HH11 1 
ATOM   44   H  HH12 . ARG A 1 14  ? -22.088 -4.243  43.347 1   78.974  ? 3   ARG A HH12 1 
ATOM   45   H  HH21 . ARG A 1 14  ? -24.759 -4.48   41.517 1   88.6    ? 3   ARG A HH21 1 
ATOM   46   H  HH22 . ARG A 1 14  ? -24.679 -4.306  43.04  1   88.631  ? 3   ARG A HH22 1 
ATOM   47   N  N    . LYS A 1 15  ? -16.959 -0.835  37.978 1   58.328  ? 4   LYS A N    1 
ATOM   48   C  CA   . LYS A 1 15  ? -15.629 -0.284  38.179 1   53.495  ? 4   LYS A CA   1 
ATOM   49   C  C    . LYS A 1 15  ? -15.707 0.623   39.412 1   50.566  ? 4   LYS A C    1 
ATOM   50   O  O    . LYS A 1 15  ? -16.394 1.633   39.343 1   45.705  ? 4   LYS A O    1 
ATOM   51   C  CB   . LYS A 1 15  ? -15.153 0.543   36.985 1   66.616  ? 4   LYS A CB   1 
ATOM   52   C  CG   . LYS A 1 15  ? -13.627 0.651   36.913 1   73.542  ? 4   LYS A CG   1 
ATOM   53   C  CD   . LYS A 1 15  ? -13.161 1.485   35.719 1   84.476  ? 4   LYS A CD   1 
ATOM   54   C  CE   . LYS A 1 15  ? -11.73  1.928   35.854 1   85.407  ? 4   LYS A CE   1 
ATOM   55   N  NZ   . LYS A 1 15  ? -11.41  2.862   34.779 1   83.104  ? 4   LYS A NZ   1 
ATOM   56   H  H    . LYS A 1 15  ? -17.563 -0.37   37.474 1   58.938  ? 4   LYS A H    1 
ATOM   57   H  HA   . LYS A 1 15  ? -14.991 -1.023  38.35  1   56.084  ? 4   LYS A HA   1 
ATOM   58   H  HB2  . LYS A 1 15  ? -15.478 0.128   36.158 1   64.769  ? 4   LYS A HB2  1 
ATOM   59   H  HB3  . LYS A 1 15  ? -15.532 1.447   37.039 1   64.591  ? 4   LYS A HB3  1 
ATOM   60   H  HG2  . LYS A 1 15  ? -13.299 1.061   37.743 1   74.265  ? 4   LYS A HG2  1 
ATOM   61   H  HG3  . LYS A 1 15  ? -13.248 -0.252  36.845 1   74.214  ? 4   LYS A HG3  1 
ATOM   62   H  HD2  . LYS A 1 15  ? -13.256 0.953   34.899 1   82.082  ? 4   LYS A HD2  1 
ATOM   63   H  HD3  . LYS A 1 15  ? -13.736 2.277   35.636 1   82.09   ? 4   LYS A HD3  1 
ATOM   64   H  HE2  . LYS A 1 15  ? -11.596 2.367   36.713 1   84.573  ? 4   LYS A HE2  1 
ATOM   65   H  HE3  . LYS A 1 15  ? -11.136 1.158   35.801 1   84.631  ? 4   LYS A HE3  1 
ATOM   66   H  HZ1  . LYS A 1 15  ? -11.935 3.598   34.844 1   83.799  ? 4   LYS A HZ1  1 
ATOM   67   H  HZ2  . LYS A 1 15  ? -11.551 2.466   33.976 1   83.808  ? 4   LYS A HZ2  1 
ATOM   68   H  HZ3  . LYS A 1 15  ? -10.541 3.111   34.839 1   83.805  ? 4   LYS A HZ3  1 
ATOM   69   N  N    . THR A 1 16  ? -15.071 0.212   40.534 1   40.693  ? 5   THR A N    1 
ATOM   70   C  CA   . THR A 1 16  ? -15.213 0.828   41.835 1   37.492  ? 5   THR A CA   1 
ATOM   71   C  C    . THR A 1 16  ? -13.885 1.475   42.231 1   35.867  ? 5   THR A C    1 
ATOM   72   O  O    . THR A 1 16  ? -12.853 0.832   42.268 1   35.588  ? 5   THR A O    1 
ATOM   73   C  CB   . THR A 1 16  ? -15.663 -0.213  42.85  1   41.636  ? 5   THR A CB   1 
ATOM   74   O  OG1  . THR A 1 16  ? -16.956 -0.672  42.488 1   40.086  ? 5   THR A OG1  1 
ATOM   75   C  CG2  . THR A 1 16  ? -15.821 0.384   44.233 1   37.241  ? 5   THR A CG2  1 
ATOM   76   H  H    . THR A 1 16  ? -14.51  -0.507  40.465 1   42.232  ? 5   THR A H    1 
ATOM   77   H  HA   . THR A 1 16  ? -15.902 1.524   41.778 1   38.588  ? 5   THR A HA   1 
ATOM   78   H  HB   . THR A 1 16  ? -15.032 -0.971  42.873 1   39.737  ? 5   THR A HB   1 
ATOM   79   H  HG1  . THR A 1 16  ? -17.517 -0.006  42.497 0   39.91   ? 5   THR A HG1  1 
ATOM   80   H  HG21 . THR A 1 16  ? -16.395 -0.188  44.771 1   38.498  ? 5   THR A HG21 1 
ATOM   81   H  HG22 . THR A 1 16  ? -16.22  1.267   44.163 1   38.485  ? 5   THR A HG22 1 
ATOM   82   H  HG23 . THR A 1 16  ? -14.95  0.456   44.658 1   38.48   ? 5   THR A HG23 1 
ATOM   83   N  N    . GLY A 1 17  ? -13.946 2.781   42.482 1   36.785  ? 6   GLY A N    1 
ATOM   84   C  CA   . GLY A 1 17  ? -12.822 3.549   42.96  1   36.293  ? 6   GLY A CA   1 
ATOM   85   C  C    . GLY A 1 17  ? -12.675 3.498   44.502 1   36.287  ? 6   GLY A C    1 
ATOM   86   O  O    . GLY A 1 17  ? -13.628 3.418   45.267 1   33.35   ? 6   GLY A O    1 
ATOM   87   H  H    . GLY A 1 17  ? -14.738 3.217   42.346 1   36.479  ? 6   GLY A H    1 
ATOM   88   H  HA2  . GLY A 1 17  ? -12.001 3.208   42.538 1   36.385  ? 6   GLY A HA2  1 
ATOM   89   H  HA3  . GLY A 1 17  ? -12.935 4.485   42.679 1   36.497  ? 6   GLY A HA3  1 
ATOM   90   N  N    . PHE A 1 18  ? -11.414 3.387   44.918 1   33.448  ? 7   PHE A N    1 
ATOM   91   C  CA   . PHE A 1 18  ? -11.02  3.447   46.309 1   30.624  ? 7   PHE A CA   1 
ATOM   92   C  C    . PHE A 1 18  ? -9.955  4.506   46.41  1   29.025  ? 7   PHE A C    1 
ATOM   93   O  O    . PHE A 1 18  ? -8.828  4.327   45.944 1   33.836  ? 7   PHE A O    1 
ATOM   94   C  CB   . PHE A 1 18  ? -10.587 2.089   46.831 1   28.996  ? 7   PHE A CB   1 
ATOM   95   C  CG   . PHE A 1 18  ? -10.404 2.056   48.339 1   31.745  ? 7   PHE A CG   1 
ATOM   96   C  CD1  . PHE A 1 18  ? -11.485 1.905   49.187 1   35.02   ? 7   PHE A CD1  1 
ATOM   97   C  CD2  . PHE A 1 18  ? -9.149  2.2     48.907 1   31.573  ? 7   PHE A CD2  1 
ATOM   98   C  CE1  . PHE A 1 18  ? -11.305 1.847   50.562 1   37.553  ? 7   PHE A CE1  1 
ATOM   99   C  CE2  . PHE A 1 18  ? -8.972  2.077   50.267 1   38.076  ? 7   PHE A CE2  1 
ATOM   100  C  CZ   . PHE A 1 18  ? -10.04  1.914   51.089 1   36.661  ? 7   PHE A CZ   1 
ATOM   101  H  H    . PHE A 1 18  ? -10.759 3.264   44.292 1   33.438  ? 7   PHE A H    1 
ATOM   102  H  HA   . PHE A 1 18  ? -11.804 3.74    46.84  1   30.56   ? 7   PHE A HA   1 
ATOM   103  H  HB2  . PHE A 1 18  ? -11.265 1.424   46.576 1   29.976  ? 7   PHE A HB2  1 
ATOM   104  H  HB3  . PHE A 1 18  ? -9.739  1.842   46.4   1   29.991  ? 7   PHE A HB3  1 
ATOM   105  H  HD1  . PHE A 1 18  ? -12.352 1.819   48.824 1   34.749  ? 7   PHE A HD1  1 
ATOM   106  H  HD2  . PHE A 1 18  ? -8.393  2.267   48.345 1   33.083  ? 7   PHE A HD2  1 
ATOM   107  H  HE1  . PHE A 1 18  ? -12.049 1.723   51.13  1   36.672  ? 7   PHE A HE1  1 
ATOM   108  H  HE2  . PHE A 1 18  ? -8.108  2.17    50.636 1   36.058  ? 7   PHE A HE2  1 
ATOM   109  H  HZ   . PHE A 1 18  ? -9.918  1.899   52.025 1   37.131  ? 7   PHE A HZ   1 
ATOM   110  N  N    . PHE A 1 19  ? -10.35  5.595   47.053 1   29.064  ? 8   PHE A N    1 
ATOM   111  C  CA   . PHE A 1 19  ? -9.484  6.741   47.201 1   28.276  ? 8   PHE A CA   1 
ATOM   112  C  C    . PHE A 1 19  ? -8.888  6.811   48.602 1   31.28   ? 8   PHE A C    1 
ATOM   113  O  O    . PHE A 1 19  ? -9.614  6.855   49.602 1   29.661  ? 8   PHE A O    1 
ATOM   114  C  CB   . PHE A 1 19  ? -10.257 8.02    46.884 1   31.291  ? 8   PHE A CB   1 
ATOM   115  C  CG   . PHE A 1 19  ? -10.676 8.208   45.433 1   30.539  ? 8   PHE A CG   1 
ATOM   116  C  CD1  . PHE A 1 19  ? -11.791 7.554   44.923 1   36.808  ? 8   PHE A CD1  1 
ATOM   117  C  CD2  . PHE A 1 19  ? -10.07  9.168   44.636 1   41.185  ? 8   PHE A CD2  1 
ATOM   118  C  CE1  . PHE A 1 19  ? -12.148 7.719   43.599 1   35.817  ? 8   PHE A CE1  1 
ATOM   119  C  CE2  . PHE A 1 19  ? -10.419 9.313   43.298 1   33.435  ? 8   PHE A CE2  1 
ATOM   120  C  CZ   . PHE A 1 19  ? -11.476 8.613   42.819 1   37.549  ? 8   PHE A CZ   1 
ATOM   121  H  H    . PHE A 1 19  ? -11.189 5.629   47.414 1   28.903  ? 8   PHE A H    1 
ATOM   122  H  HA   . PHE A 1 19  ? -8.747  6.659   46.548 1   29.573  ? 8   PHE A HA   1 
ATOM   123  H  HB2  . PHE A 1 19  ? -11.063 8.038   47.446 1   30.441  ? 8   PHE A HB2  1 
ATOM   124  H  HB3  . PHE A 1 19  ? -9.702  8.787   47.15  1   30.529  ? 8   PHE A HB3  1 
ATOM   125  H  HD1  . PHE A 1 19  ? -12.235 6.908   45.45  1   35.05   ? 8   PHE A HD1  1 
ATOM   126  H  HD2  . PHE A 1 19  ? -9.313  9.625   44.966 1   36.506  ? 8   PHE A HD2  1 
ATOM   127  H  HE1  . PHE A 1 19  ? -12.88  7.24    43.245 1   36.395  ? 8   PHE A HE1  1 
ATOM   128  H  HE2  . PHE A 1 19  ? -9.975  9.944   42.754 1   36.016  ? 8   PHE A HE2  1 
ATOM   129  H  HZ   . PHE A 1 19  ? -11.751 8.745   41.926 1   36.128  ? 8   PHE A HZ   1 
ATOM   130  N  N    . PHE A 1 20  ? -7.54   6.76    48.694 1   30.501  ? 9   PHE A N    1 
ATOM   131  C  CA   . PHE A 1 20  ? -6.937  6.711   50.019 1   28.913  ? 9   PHE A CA   1 
ATOM   132  C  C    . PHE A 1 20  ? -5.553  7.303   49.839 1   31.768  ? 9   PHE A C    1 
ATOM   133  O  O    . PHE A 1 20  ? -5.025  7.374   48.703 1   29.416  ? 9   PHE A O    1 
ATOM   134  C  CB   . PHE A 1 20  ? -6.986  5.277   50.555 1   33.27   ? 9   PHE A CB   1 
ATOM   135  C  CG   . PHE A 1 20  ? -5.829  4.435   50.06  1   36.367  ? 9   PHE A CG   1 
ATOM   136  C  CD1  . PHE A 1 20  ? -5.812  3.964   48.763 1   36.563  ? 9   PHE A CD1  1 
ATOM   137  C  CD2  . PHE A 1 20  ? -4.697  4.252   50.836 1   36.904  ? 9   PHE A CD2  1 
ATOM   138  C  CE1  . PHE A 1 20  ? -4.736  3.207   48.283 1   42.902  ? 9   PHE A CE1  1 
ATOM   139  C  CE2  . PHE A 1 20  ? -3.637  3.451   50.387 1   42.297  ? 9   PHE A CE2  1 
ATOM   140  C  CZ   . PHE A 1 20  ? -3.645  2.952   49.077 1   36.207  ? 9   PHE A CZ   1 
ATOM   141  H  H    . PHE A 1 20  ? -7.012  6.754   47.948 1   30.312  ? 9   PHE A H    1 
ATOM   142  H  HA   . PHE A 1 20  ? -7.457  7.298   50.63  1   30.479  ? 9   PHE A HA   1 
ATOM   143  H  HB2  . PHE A 1 20  ? -6.966  5.305   51.537 1   32.939  ? 9   PHE A HB2  1 
ATOM   144  H  HB3  . PHE A 1 20  ? -7.831  4.86    50.274 1   32.881  ? 9   PHE A HB3  1 
ATOM   145  H  HD1  . PHE A 1 20  ? -6.56   4.112   48.207 1   37.877  ? 9   PHE A HD1  1 
ATOM   146  H  HD2  . PHE A 1 20  ? -4.695  4.564   51.727 1   37.899  ? 9   PHE A HD2  1 
ATOM   147  H  HE1  . PHE A 1 20  ? -4.766  2.862   47.405 1   39.69   ? 9   PHE A HE1  1 
ATOM   148  H  HE2  . PHE A 1 20  ? -2.887  3.31    50.939 1   39.517  ? 9   PHE A HE2  1 
ATOM   149  H  HZ   . PHE A 1 20  ? -2.918  2.446   48.749 1   38.995  ? 9   PHE A HZ   1 
ATOM   150  N  N    . ASP A 1 21  ? -4.973  7.693   50.943 1   26.825  ? 10  ASP A N    1 
ATOM   151  C  CA   . ASP A 1 21  ? -3.59   8.16    50.917 1   29.19   ? 10  ASP A CA   1 
ATOM   152  C  C    . ASP A 1 21  ? -2.958  7.864   52.259 1   30.342  ? 10  ASP A C    1 
ATOM   153  O  O    . ASP A 1 21  ? -3.537  8.146   53.284 1   32.828  ? 10  ASP A O    1 
ATOM   154  C  CB   . ASP A 1 21  ? -3.461  9.66    50.618 1   28.023  ? 10  ASP A CB   1 
ATOM   155  C  CG   . ASP A 1 21  ? -2.04   10.055  50.22  1   34.204  ? 10  ASP A CG   1 
ATOM   156  O  OD1  . ASP A 1 21  ? -1.15   9.98    51.096 1   32.597  ? 10  ASP A OD1  1 
ATOM   157  O  OD2  . ASP A 1 21  ? -1.759  10.32   49.019 1   33.305  ? 10  ASP A OD2  1 
ATOM   158  H  H    . ASP A 1 21  ? -5.429  7.679   51.736 1   28.495  ? 10  ASP A H    1 
ATOM   159  H  HA   . ASP A 1 21  ? -3.104  7.66    50.222 1   28.802  ? 10  ASP A HA   1 
ATOM   160  H  HB2  . ASP A 1 21  ? -4.068  9.895   49.885 1   29.603  ? 10  ASP A HB2  1 
ATOM   161  H  HB3  . ASP A 1 21  ? -3.721  10.175  51.41  1   29.606  ? 10  ASP A HB3  1 
ATOM   162  N  N    . GLU A 1 22  ? -1.735  7.321   52.253 1   33.356  ? 11  GLU A N    1 
ATOM   163  C  CA   . GLU A 1 22  ? -1.031  6.998   53.48  1   32.83   ? 11  GLU A CA   1 
ATOM   164  C  C    . GLU A 1 22  ? -0.933  8.201   54.429 1   34.102  ? 11  GLU A C    1 
ATOM   165  O  O    . GLU A 1 22  ? -0.992  8.036   55.68  1   29.222  ? 11  GLU A O    1 
ATOM   166  C  CB   . GLU A 1 22  ? 0.371   6.454   53.137 1   33.306  ? 11  GLU A CB   1 
ATOM   167  C  CG   . GLU A 1 22  ? 1.226   6.402   54.399 1   35.644  ? 11  GLU A CG   1 
ATOM   168  C  CD   . GLU A 1 22  ? 0.905   5.303   55.403 1   35.699  ? 11  GLU A CD   1 
ATOM   169  O  OE1  . GLU A 1 22  ? 0.202   4.295   55.08  1   38.231  ? 11  GLU A OE1  1 
ATOM   170  O  OE2  . GLU A 1 22  ? 1.369   5.498   56.546 1   29.94   ? 11  GLU A OE2  1 
ATOM   171  H  H    . GLU A 1 22  ? -1.327  7.147   51.453 1   32.453  ? 11  GLU A H    1 
ATOM   172  H  HA   . GLU A 1 22  ? -1.536  6.281   53.941 1   33.248  ? 11  GLU A HA   1 
ATOM   173  H  HB2  . GLU A 1 22  ? 0.287   5.562   52.744 1   33.77   ? 11  GLU A HB2  1 
ATOM   174  H  HB3  . GLU A 1 22  ? 0.791   7.04    52.474 1   33.716  ? 11  GLU A HB3  1 
ATOM   175  H  HG2  . GLU A 1 22  ? 2.163   6.293   54.129 1   35.093  ? 11  GLU A HG2  1 
ATOM   176  H  HG3  . GLU A 1 22  ? 1.17    7.263   54.859 1   35.03   ? 11  GLU A HG3  1 
ATOM   177  N  N    . ARG A 1 23  ? -0.785  9.404   53.872 1   25.545  ? 12  ARG A N    1 
ATOM   178  C  CA   . ARG A 1 23  ? -0.692  10.563  54.732 1   27.339  ? 12  ARG A CA   1 
ATOM   179  C  C    . ARG A 1 23  ? -1.902  10.811  55.606 1   29.089  ? 12  ARG A C    1 
ATOM   180  O  O    . ARG A 1 23  ? -1.775  11.356  56.705 1   28.87   ? 12  ARG A O    1 
ATOM   181  C  CB   . ARG A 1 23  ? -0.437  11.825  53.918 1   29.724  ? 12  ARG A CB   1 
ATOM   182  C  CG   . ARG A 1 23  ? 0.95    11.889  53.325 1   36.805  ? 12  ARG A CG   1 
ATOM   183  C  CD   . ARG A 1 23  ? 1.083   13.125  52.357 1   44.042  ? 12  ARG A CD   1 
ATOM   184  N  NE   . ARG A 1 23  ? 0.509   12.663  51.078 1   50.303  ? 12  ARG A NE   1 
ATOM   185  C  CZ   . ARG A 1 23  ? 0.154   13.444  50.052 1   52.861  ? 12  ARG A CZ   1 
ATOM   186  N  NH1  . ARG A 1 23  ? 0.345   14.758  50.128 1   52.5    ? 12  ARG A NH1  1 
ATOM   187  N  NH2  . ARG A 1 23  ? -0.458  12.959  48.997 1   40.971  ? 12  ARG A NH2  1 
ATOM   188  H  H    . ARG A 1 23  ? -0.73   9.504   52.965 1   27.886  ? 12  ARG A H    1 
ATOM   189  H  HA   . ARG A 1 23  ? 0.09    10.433  55.327 1   27.755  ? 12  ARG A HA   1 
ATOM   190  H  HB2  . ARG A 1 23  ? -1.094  11.871  53.191 1   30.637  ? 12  ARG A HB2  1 
ATOM   191  H  HB3  . ARG A 1 23  ? -0.572  12.609  54.493 1   30.631  ? 12  ARG A HB3  1 
ATOM   192  H  HG2  . ARG A 1 23  ? 1.611   11.973  54.048 1   36.453  ? 12  ARG A HG2  1 
ATOM   193  H  HG3  . ARG A 1 23  ? 1.137   11.063  52.83  1   36.529  ? 12  ARG A HG3  1 
ATOM   194  H  HD2  . ARG A 1 23  ? 0.579   13.894  52.693 1   43.772  ? 12  ARG A HD2  1 
ATOM   195  H  HD3  . ARG A 1 23  ? 2.02    13.38   52.232 1   43.741  ? 12  ARG A HD3  1 
ATOM   196  H  HE   . ARG A 1 23  ? 0.389   11.807  50.972 1   49.019  ? 12  ARG A HE   1 
ATOM   197  H  HH11 . ARG A 1 23  ? 1.158   15.077  50.271 1   52.555  ? 12  ARG A HH11 1 
ATOM   198  H  HH12 . ARG A 1 23  ? -0.342  15.307  50.033 1   52.592  ? 12  ARG A HH12 1 
ATOM   199  H  HH21 . ARG A 1 23  ? -0.29   12.131  48.733 1   44.372  ? 12  ARG A HH21 1 
ATOM   200  H  HH22 . ARG A 1 23  ? -1.036  13.461  48.554 1   44.39   ? 12  ARG A HH22 1 
ATOM   201  N  N    . CYS A 1 24  ? -3.094  10.388  55.186 1   26.173  ? 13  CYS A N    1 
ATOM   202  C  CA   . CYS A 1 24  ? -4.197  10.537  56.113 1   26.085  ? 13  CYS A CA   1 
ATOM   203  C  C    . CYS A 1 24  ? -4.063  9.764   57.419 1   35.103  ? 13  CYS A C    1 
ATOM   204  O  O    . CYS A 1 24  ? -4.765  10.075  58.384 1   32.863  ? 13  CYS A O    1 
ATOM   205  C  CB   . CYS A 1 24  ? -5.498  10.109  55.455 1   29.143  ? 13  CYS A CB   1 
ATOM   206  S  SG   . CYS A 1 24  ? -5.847  11.232  54.085 1   40.144  ? 13  CYS A SG   1 
ATOM   207  H  H    . CYS A 1 24  ? -3.224  10.027  54.356 1   26.862  ? 13  CYS A H    1 
ATOM   208  H  HA   . CYS A 1 24  ? -4.277  11.499  56.333 1   28.214  ? 13  CYS A HA   1 
ATOM   209  H  HB2  . CYS A 1 24  ? -5.417  9.191   55.113 1   30.182  ? 13  CYS A HB2  1 
ATOM   210  H  HB3  . CYS A 1 24  ? -6.234  10.143  56.104 1   30.22   ? 13  CYS A HB3  1 
ATOM   211  H  HG   . CYS A 1 24  ? -6.888  10.725  53.72  0   40.03   ? 13  CYS A HG   1 
ATOM   212  N  N    . PHE A 1 25  ? -3.288  8.686   57.435 1   31.22   ? 14  PHE A N    1 
ATOM   213  C  CA   . PHE A 1 25  ? -3.082  7.96    58.679 1   33.577  ? 14  PHE A CA   1 
ATOM   214  C  C    . PHE A 1 25  ? -2.092  8.649   59.61  1   33.446  ? 14  PHE A C    1 
ATOM   215  O  O    . PHE A 1 25  ? -1.929  8.191   60.741 1   28.575  ? 14  PHE A O    1 
ATOM   216  C  CB   . PHE A 1 25  ? -2.502  6.575   58.344 1   34.649  ? 14  PHE A CB   1 
ATOM   217  C  CG   . PHE A 1 25  ? -3.381  5.75    57.435 1   31.111  ? 14  PHE A CG   1 
ATOM   218  C  CD1  . PHE A 1 25  ? -4.748  5.618   57.691 1   36.916  ? 14  PHE A CD1  1 
ATOM   219  C  CD2  . PHE A 1 25  ? -2.852  5.113   56.327 1   37.959  ? 14  PHE A CD2  1 
ATOM   220  C  CE1  . PHE A 1 25  ? -5.564  4.803   56.912 1   34.274  ? 14  PHE A CE1  1 
ATOM   221  C  CE2  . PHE A 1 25  ? -3.673  4.32    55.539 1   35.654  ? 14  PHE A CE2  1 
ATOM   222  C  CZ   . PHE A 1 25  ? -5.033  4.165   55.83  1   35.729  ? 14  PHE A CZ   1 
ATOM   223  H  H    . PHE A 1 25  ? -2.885  8.392   56.67  1   32.523  ? 14  PHE A H    1 
ATOM   224  H  HA   . PHE A 1 25  ? -3.951  7.849   59.147 1   33.305  ? 14  PHE A HA   1 
ATOM   225  H  HB2  . PHE A 1 25  ? -1.626  6.698   57.916 1   33.569  ? 14  PHE A HB2  1 
ATOM   226  H  HB3  . PHE A 1 25  ? -2.363  6.083   59.183 1   33.538  ? 14  PHE A HB3  1 
ATOM   227  H  HD1  . PHE A 1 25  ? -5.111  6.031   58.457 1   34.879  ? 14  PHE A HD1  1 
ATOM   228  H  HD2  . PHE A 1 25  ? -1.932  5.184   56.135 1   35.714  ? 14  PHE A HD2  1 
ATOM   229  H  HE1  . PHE A 1 25  ? -6.483  4.727   57.106 1   35.223  ? 14  PHE A HE1  1 
ATOM   230  H  HE2  . PHE A 1 25  ? -3.307  3.881   54.788 1   36.149  ? 14  PHE A HE2  1 
ATOM   231  H  HZ   . PHE A 1 25  ? -5.584  3.646   55.266 1   35.369  ? 14  PHE A HZ   1 
ATOM   232  N  N    . TRP A 1 26  ? -1.424  9.724   59.142 1   33.484  ? 15  TRP A N    1 
ATOM   233  C  CA   . TRP A 1 26  ? -0.454  10.411  59.962 1   27.112  ? 15  TRP A CA   1 
ATOM   234  C  C    . TRP A 1 26  ? -1.049  11.507  60.833 1   31.636  ? 15  TRP A C    1 
ATOM   235  O  O    . TRP A 1 26  ? -0.328  12.05   61.666 1   32.654  ? 15  TRP A O    1 
ATOM   236  C  CB   . TRP A 1 26  ? 0.716   10.948  59.17  1   30.009  ? 15  TRP A CB   1 
ATOM   237  C  CG   . TRP A 1 26  ? 1.604   9.875   58.603 1   29.045  ? 15  TRP A CG   1 
ATOM   238  C  CD1  . TRP A 1 26  ? 1.235   8.666   58.063 1   30.847  ? 15  TRP A CD1  1 
ATOM   239  C  CD2  . TRP A 1 26  ? 3.035   9.885   58.578 1   25.547  ? 15  TRP A CD2  1 
ATOM   240  N  NE1  . TRP A 1 26  ? 2.345   7.961   57.67  1   30.974  ? 15  TRP A NE1  1 
ATOM   241  C  CE2  . TRP A 1 26  ? 3.456   8.666   57.995 1   27.424  ? 15  TRP A CE2  1 
ATOM   242  C  CE3  . TRP A 1 26  ? 3.97    10.798  58.995 1   23.979  ? 15  TRP A CE3  1 
ATOM   243  C  CZ2  . TRP A 1 26  ? 4.784   8.335   57.795 1   29.16   ? 15  TRP A CZ2  1 
ATOM   244  C  CZ3  . TRP A 1 26  ? 5.293   10.447  58.856 1   30.88   ? 15  TRP A CZ3  1 
ATOM   245  C  CH2  . TRP A 1 26  ? 5.688   9.262   58.241 1   26.648  ? 15  TRP A CH2  1 
ATOM   246  H  H    . TRP A 1 26  ? -1.571  10.022  58.291 1   31.912  ? 15  TRP A H    1 
ATOM   247  H  HA   . TRP A 1 26  ? -0.078  9.73    60.582 1   29.629  ? 15  TRP A HA   1 
ATOM   248  H  HB2  . TRP A 1 26  ? 0.369   11.495  58.434 1   29.105  ? 15  TRP A HB2  1 
ATOM   249  H  HB3  . TRP A 1 26  ? 1.252   11.526  59.753 1   29.132  ? 15  TRP A HB3  1 
ATOM   250  H  HD1  . TRP A 1 26  ? 0.349   8.372   57.936 1   30.409  ? 15  TRP A HD1  1 
ATOM   251  H  HE1  . TRP A 1 26  ? 2.336   7.17    57.301 1   30.023  ? 15  TRP A HE1  1 
ATOM   252  H  HE3  . TRP A 1 26  ? 3.715   11.604  59.411 1   25.875  ? 15  TRP A HE3  1 
ATOM   253  H  HZ2  . TRP A 1 26  ? 5.046   7.517   57.409 1   28.159  ? 15  TRP A HZ2  1 
ATOM   254  H  HZ3  . TRP A 1 26  ? 5.954   11.064  59.117 1   28.094  ? 15  TRP A HZ3  1 
ATOM   255  H  HH2  . TRP A 1 26  ? 6.606   9.081   58.146 1   28.136  ? 15  TRP A HH2  1 
ATOM   256  N  N    . HIS A 1 27  ? -2.326  11.828  60.689 1   31.614  ? 16  HIS A N    1 
ATOM   257  C  CA   . HIS A 1 27  ? -2.893  12.863  61.535 1   32.783  ? 16  HIS A CA   1 
ATOM   258  C  C    . HIS A 1 27  ? -3.039  12.344  62.962 1   32.609  ? 16  HIS A C    1 
ATOM   259  O  O    . HIS A 1 27  ? -3.31   11.157  63.186 1   35.346  ? 16  HIS A O    1 
ATOM   260  C  CB   . HIS A 1 27  ? -4.265  13.252  60.993 1   33.09   ? 16  HIS A CB   1 
ATOM   261  C  CG   . HIS A 1 27  ? -5.249  13.826  61.934 1   36.431  ? 16  HIS A CG   1 
ATOM   262  N  ND1  . HIS A 1 27  ? -5.177  15.121  62.396 1   35.101  ? 16  HIS A ND1  1 
ATOM   263  C  CD2  . HIS A 1 27  ? -6.38   13.289  62.474 1   35.674  ? 16  HIS A CD2  1 
ATOM   264  C  CE1  . HIS A 1 27  ? -6.261  15.364  63.139 1   33.056  ? 16  HIS A CE1  1 
ATOM   265  N  NE2  . HIS A 1 27  ? -6.995  14.258  63.227 1   30.86   ? 16  HIS A NE2  1 
ATOM   266  H  H    . HIS A 1 27  ? -2.848  11.412  60.065 1   31.889  ? 16  HIS A H    1 
ATOM   267  H  HA   . HIS A 1 27  ? -2.296  13.651  61.537 1   32.602  ? 16  HIS A HA   1 
ATOM   268  H  HB2  . HIS A 1 27  ? -4.13   13.894  60.262 1   33.768  ? 16  HIS A HB2  1 
ATOM   269  H  HB3  . HIS A 1 27  ? -4.667  12.458  60.58  1   33.725  ? 16  HIS A HB3  1 
ATOM   270  H  HD1  . HIS A 1 27  ? -4.532  15.691  62.22  0   34.74   ? 16  HIS A HD1  1 
ATOM   271  H  HD2  . HIS A 1 27  ? -6.704  12.42   62.337 1   34.661  ? 16  HIS A HD2  1 
ATOM   272  H  HE1  . HIS A 1 27  ? -6.428  16.17   63.596 1   33.021  ? 16  HIS A HE1  1 
ATOM   273  H  HE2  . HIS A 1 27  ? -7.742  14.167  63.679 0   30.58   ? 16  HIS A HE2  1 
ATOM   274  N  N    . SER A 1 28  ? -2.759  13.196  63.922 1   33.541  ? 17  SER A N    1 
ATOM   275  C  CA   . SER A 1 28  ? -2.804  12.792  65.333 1   35.265  ? 17  SER A CA   1 
ATOM   276  C  C    . SER A 1 28  ? -3.454  13.911  66.154 1   32.974  ? 17  SER A C    1 
ATOM   277  O  O    . SER A 1 28  ? -3.627  15.051  65.701 1   33.405  ? 17  SER A O    1 
ATOM   278  C  CB   . SER A 1 28  ? -1.409  12.46   65.917 1   32.313  ? 17  SER A CB   1 
ATOM   279  O  OG   . SER A 1 28  ? -0.501  13.565  65.865 1   40.682  ? 17  SER A OG   1 
ATOM   280  H  H    . SER A 1 28  ? -2.532  14.057  63.714 1   33.669  ? 17  SER A H    1 
ATOM   281  H  HA   . SER A 1 28  ? -3.373  11.985  65.409 1   34.022  ? 17  SER A HA   1 
ATOM   282  H  HB2  . SER A 1 28  ? -1.509  12.173  66.843 1   34.849  ? 17  SER A HB2  1 
ATOM   283  H  HB3  . SER A 1 28  ? -1.028  11.713  65.418 1   34.823  ? 17  SER A HB3  1 
ATOM   284  H  HG   . SER A 1 28  ? 0.251   13.322  66.192 0   40.85   ? 17  SER A HG   1 
ATOM   285  N  N    . THR A 1 29  ? -3.692  13.6    67.413 1   37.379  ? 18  THR A N    1 
ATOM   286  C  CA   . THR A 1 29  ? -4.625  14.345  68.227 1   42.687  ? 18  THR A CA   1 
ATOM   287  C  C    . THR A 1 29  ? -4.09   14.424  69.645 1   39.313  ? 18  THR A C    1 
ATOM   288  O  O    . THR A 1 29  ? -4.878  14.701  70.499 1   38.353  ? 18  THR A O    1 
ATOM   289  C  CB   . THR A 1 29  ? -6.048  13.724  68.226 1   53.485  ? 18  THR A CB   1 
ATOM   290  O  OG1  . THR A 1 29  ? -6.168  12.364  68.653 1   55.985  ? 18  THR A OG1  1 
ATOM   291  C  CG2  . THR A 1 29  ? -6.754  13.805  66.876 1   55.257  ? 18  THR A CG2  1 
ATOM   292  H  H    . THR A 1 29  ? -3.283  12.868  67.777 1   37.31   ? 18  THR A H    1 
ATOM   293  H  HA   . THR A 1 29  ? -4.687  15.257  67.869 1   42.55   ? 18  THR A HA   1 
ATOM   294  H  HB   . THR A 1 29  ? -6.594  14.274  68.836 1   51.968  ? 18  THR A HB   1 
ATOM   295  H  HG1  . THR A 1 29  ? -5.691  11.867  68.142 0   55.82   ? 18  THR A HG1  1 
ATOM   296  H  HG21 . THR A 1 29  ? -7.683  13.54   66.978 1   54.673  ? 18  THR A HG21 1 
ATOM   297  H  HG22 . THR A 1 29  ? -6.316  13.21   66.244 1   54.574  ? 18  THR A HG22 1 
ATOM   298  H  HG23 . THR A 1 29  ? -6.713  14.717  66.542 1   54.589  ? 18  THR A HG23 1 
ATOM   299  N  N    . GLY A 1 30  ? -2.821  14.153  69.935 1   34.671  ? 19  GLY A N    1 
ATOM   300  C  CA   . GLY A 1 30  ? -2.388  14.171  71.334 1   39.098  ? 19  GLY A CA   1 
ATOM   301  C  C    . GLY A 1 30  ? -2.697  12.877  72.142 1   39.674  ? 19  GLY A C    1 
ATOM   302  O  O    . GLY A 1 30  ? -3.087  11.844  71.62  1   43.257  ? 19  GLY A O    1 
ATOM   303  H  H    . GLY A 1 30  ? -2.213  13.974  69.277 1   36.708  ? 19  GLY A H    1 
ATOM   304  H  HA2  . GLY A 1 30  ? -1.415  14.328  71.352 1   38.116  ? 19  GLY A HA2  1 
ATOM   305  H  HA3  . GLY A 1 30  ? -2.815  14.937  71.784 1   38.14   ? 19  GLY A HA3  1 
ATOM   306  N  N    . LEU A 1 31  ? -2.646  13.009  73.46  1   43.06   ? 20  LEU A N    1 
ATOM   307  C  CA   . LEU A 1 31  ? -2.711  11.912  74.399 1   37.889  ? 20  LEU A CA   1 
ATOM   308  C  C    . LEU A 1 31  ? -4.078  11.892  75.075 1   34.124  ? 20  LEU A C    1 
ATOM   309  O  O    . LEU A 1 31  ? -4.455  12.847  75.712 1   33.552  ? 20  LEU A O    1 
ATOM   310  C  CB   . LEU A 1 31  ? -1.606  12.109  75.414 1   41.77   ? 20  LEU A CB   1 
ATOM   311  C  CG   . LEU A 1 31  ? -1.374  10.912  76.341 1   54.306  ? 20  LEU A CG   1 
ATOM   312  C  CD1  . LEU A 1 31  ? -0.871  9.77    75.483 1   55.576  ? 20  LEU A CD1  1 
ATOM   313  C  CD2  . LEU A 1 31  ? -0.413  11.307  77.459 1   52.539  ? 20  LEU A CD2  1 
ATOM   314  H  H    . LEU A 1 31  ? -2.567  13.854  73.8   1   40.98   ? 20  LEU A H    1 
ATOM   315  H  HA   . LEU A 1 31  ? -2.57   11.065  73.91  1   38.847  ? 20  LEU A HA   1 
ATOM   316  H  HB2  . LEU A 1 31  ? -0.77   12.303  74.931 1   43.467  ? 20  LEU A HB2  1 
ATOM   317  H  HB3  . LEU A 1 31  ? -1.827  12.894  75.966 1   43.309  ? 20  LEU A HB3  1 
ATOM   318  H  HG   . LEU A 1 31  ? -2.24   10.649  76.744 1   51.475  ? 20  LEU A HG   1 
ATOM   319  H  HD11 . LEU A 1 31  ? -1.621  9.343   75.036 1   54.903  ? 20  LEU A HD11 1 
ATOM   320  H  HD12 . LEU A 1 31  ? -0.42   9.118   76.045 1   55.091  ? 20  LEU A HD12 1 
ATOM   321  H  HD13 . LEU A 1 31  ? -0.247  10.106  74.818 1   54.943  ? 20  LEU A HD13 1 
ATOM   322  H  HD21 . LEU A 1 31  ? -0.797  12.037  77.974 1   53.053  ? 20  LEU A HD21 1 
ATOM   323  H  HD22 . LEU A 1 31  ? 0.433   11.593  77.075 1   53.053  ? 20  LEU A HD22 1 
ATOM   324  H  HD23 . LEU A 1 31  ? -0.262  10.545  78.042 1   53.053  ? 20  LEU A HD23 1 
ATOM   325  N  N    . HIS A 1 32  ? -4.833  10.812  74.849 1   27.556  ? 21  HIS A N    1 
ATOM   326  C  CA   . HIS A 1 32  ? -6.127  10.629  75.46  1   32.21   ? 21  HIS A CA   1 
ATOM   327  C  C    . HIS A 1 32  ? -6.175  9.236   76.086 1   33.444  ? 21  HIS A C    1 
ATOM   328  O  O    . HIS A 1 32  ? -5.538  8.296   75.626 1   36.788  ? 21  HIS A O    1 
ATOM   329  C  CB   . HIS A 1 32  ? -7.229  10.738  74.393 1   32.655  ? 21  HIS A CB   1 
ATOM   330  C  CG   . HIS A 1 32  ? -7.41   12.085  73.853 1   38.442  ? 21  HIS A CG   1 
ATOM   331  N  ND1  . HIS A 1 32  ? -8.523  12.89   74.141 1   44.428  ? 21  HIS A ND1  1 
ATOM   332  C  CD2  . HIS A 1 32  ? -6.671  12.697  72.968 1   41.022  ? 21  HIS A CD2  1 
ATOM   333  C  CE1  . HIS A 1 32  ? -8.364  14.015  73.486 1   46.869  ? 21  HIS A CE1  1 
ATOM   334  N  NE2  . HIS A 1 32  ? -7.231  13.92   72.803 1   42.385  ? 21  HIS A NE2  1 
ATOM   335  H  H    . HIS A 1 32  ? -4.522  10.163  74.285 1   30.313  ? 21  HIS A H    1 
ATOM   336  H  HA   . HIS A 1 32  ? -6.267  11.303  76.169 1   31.656  ? 21  HIS A HA   1 
ATOM   337  H  HB2  . HIS A 1 32  ? -7.011  10.128  73.655 1   33.845  ? 21  HIS A HB2  1 
ATOM   338  H  HB3  . HIS A 1 32  ? -8.077  10.438  74.786 1   33.843  ? 21  HIS A HB3  1 
ATOM   339  H  HD1  . HIS A 1 32  ? -9.197  12.684  74.658 0   43.78   ? 21  HIS A HD1  1 
ATOM   340  H  HD2  . HIS A 1 32  ? -5.854  12.407  72.611 1   40.704  ? 21  HIS A HD2  1 
ATOM   341  H  HE1  . HIS A 1 32  ? -8.944  14.756  73.502 1   45.126  ? 21  HIS A HE1  1 
ATOM   342  H  HE2  . HIS A 1 32  ? -6.889  14.581  72.323 0   42.26   ? 21  HIS A HE2  1 
ATOM   343  N  N    . ALA A 1 33  ? -7.06   9.097   77.069 1   33.038  ? 22  ALA A N    1 
ATOM   344  C  CA   . ALA A 1 33  ? -7.394  7.812   77.634 1   35.75   ? 22  ALA A CA   1 
ATOM   345  C  C    . ALA A 1 33  ? -8.708  7.414   76.979 1   34.376  ? 22  ALA A C    1 
ATOM   346  O  O    . ALA A 1 33  ? -9.766  7.969   77.307 1   35.096  ? 22  ALA A O    1 
ATOM   347  C  CB   . ALA A 1 33  ? -7.487  7.974   79.175 1   38.827  ? 22  ALA A CB   1 
ATOM   348  H  H    . ALA A 1 33  ? -7.475  9.84    77.401 1   33.737  ? 22  ALA A H    1 
ATOM   349  H  HA   . ALA A 1 33  ? -6.689  7.149   77.4   1   35.446  ? 22  ALA A HA   1 
ATOM   350  H  HB1  . ALA A 1 33  ? -6.63   8.271   79.524 1   37.906  ? 22  ALA A HB1  1 
ATOM   351  H  HB2  . ALA A 1 33  ? -8.167  8.633   79.394 1   37.895  ? 22  ALA A HB2  1 
ATOM   352  H  HB3  . ALA A 1 33  ? -7.722  7.123   79.58  1   37.906  ? 22  ALA A HB3  1 
ATOM   353  N  N    . VAL A 1 34  ? -8.572  6.607   75.947 1   34.239  ? 23  VAL A N    1 
ATOM   354  C  CA   . VAL A 1 34  ? -9.624  6.292   75.013 1   34.408  ? 23  VAL A CA   1 
ATOM   355  C  C    . VAL A 1 34  ? -10.022 7.575   74.317 1   35.586  ? 23  VAL A C    1 
ATOM   356  O  O    . VAL A 1 34  ? -9.28   7.963   73.445 1   39.659  ? 23  VAL A O    1 
ATOM   357  C  CB   . VAL A 1 34  ? -10.788 5.551   75.693 1   37.201  ? 23  VAL A CB   1 
ATOM   358  C  CG1  . VAL A 1 34  ? -11.764 5.061   74.656 1   37.659  ? 23  VAL A CG1  1 
ATOM   359  C  CG2  . VAL A 1 34  ? -10.197 4.36    76.446 1   40.064  ? 23  VAL A CG2  1 
ATOM   360  H  H    . VAL A 1 34  ? -7.756  6.216   75.812 1   34.331  ? 23  VAL A H    1 
ATOM   361  H  HA   . VAL A 1 34  ? -9.248  5.694   74.338 1   35.153  ? 23  VAL A HA   1 
ATOM   362  H  HB   . VAL A 1 34  ? -11.231 6.163   76.324 1   37.231  ? 23  VAL A HB   1 
ATOM   363  H  HG11 . VAL A 1 34  ? -11.288 4.56    73.972 1   37.505  ? 23  VAL A HG11 1 
ATOM   364  H  HG12 . VAL A 1 34  ? -12.214 5.818   74.246 1   37.509  ? 23  VAL A HG12 1 
ATOM   365  H  HG13 . VAL A 1 34  ? -12.424 4.484   75.077 1   37.526  ? 23  VAL A HG13 1 
ATOM   366  H  HG21 . VAL A 1 34  ? -10.91  3.753   76.706 1   39.153  ? 23  VAL A HG21 1 
ATOM   367  H  HG22 . VAL A 1 34  ? -9.735  4.673   77.242 1   39.129  ? 23  VAL A HG22 1 
ATOM   368  H  HG23 . VAL A 1 34  ? -9.568  3.891   75.872 1   39.126  ? 23  VAL A HG23 1 
ATOM   369  N  N    . THR A 1 35  ? -11.148 8.233   74.661 1   37.625  ? 24  THR A N    1 
ATOM   370  C  CA   . THR A 1 35  ? -11.383 9.557   74.103 1   37.266  ? 24  THR A CA   1 
ATOM   371  C  C    . THR A 1 35  ? -11.421 10.645  75.169 1   43.058  ? 24  THR A C    1 
ATOM   372  O  O    . THR A 1 35  ? -11.666 11.783  74.826 1   36.91   ? 24  THR A O    1 
ATOM   373  C  CB   . THR A 1 35  ? -12.667 9.588   73.278 1   51.745  ? 24  THR A CB   1 
ATOM   374  O  OG1  . THR A 1 35  ? -13.756 9.229   74.126 1   36.195  ? 24  THR A OG1  1 
ATOM   375  C  CG2  . THR A 1 35  ? -12.562 8.696   72.05  1   46.233  ? 24  THR A CG2  1 
ATOM   376  H  H    . THR A 1 35  ? -11.762 7.864   75.228 1   37.051  ? 24  THR A H    1 
ATOM   377  H  HA   . THR A 1 35  ? -10.64  9.762   73.497 1   40.724  ? 24  THR A HA   1 
ATOM   378  H  HB   . THR A 1 35  ? -12.812 10.51   72.957 1   44.464  ? 24  THR A HB   1 
ATOM   379  H  HG1  . THR A 1 35  ? -13.63  8.426   74.413 0   36.28   ? 24  THR A HG1  1 
ATOM   380  H  HG21 . THR A 1 35  ? -13.373 8.776   71.52  1   47.782  ? 24  THR A HG21 1 
ATOM   381  H  HG22 . THR A 1 35  ? -12.448 7.772   72.328 1   47.735  ? 24  THR A HG22 1 
ATOM   382  H  HG23 . THR A 1 35  ? -11.798 8.97    71.514 1   47.782  ? 24  THR A HG23 1 
ATOM   383  N  N    . LEU A 1 36  ? -11.12  10.33   76.428 1   35.102  ? 25  LEU A N    1 
ATOM   384  C  CA   . LEU A 1 36  ? -11.017 11.378  77.417 1   32.669  ? 25  LEU A CA   1 
ATOM   385  C  C    . LEU A 1 36  ? -9.649  12.053  77.378 1   37.5    ? 25  LEU A C    1 
ATOM   386  O  O    . LEU A 1 36  ? -8.639  11.395  77.433 1   35.296  ? 25  LEU A O    1 
ATOM   387  C  CB   . LEU A 1 36  ? -11.212 10.789  78.801 1   35.005  ? 25  LEU A CB   1 
ATOM   388  C  CG   . LEU A 1 36  ? -12.64  10.507  79.256 1   45.572  ? 25  LEU A CG   1 
ATOM   389  C  CD1  . LEU A 1 36  ? -12.648 9.762   80.589 1   46.643  ? 25  LEU A CD1  1 
ATOM   390  C  CD2  . LEU A 1 36  ? -13.31  11.834  79.458 1   52.505  ? 25  LEU A CD2  1 
ATOM   391  H  H    . LEU A 1 36  ? -10.975 9.461   76.672 1   36.278  ? 25  LEU A H    1 
ATOM   392  H  HA   . LEU A 1 36  ? -11.723 12.045  77.244 1   34.772  ? 25  LEU A HA   1 
ATOM   393  H  HB2  . LEU A 1 36  ? -10.704 9.946   78.847 1   36.612  ? 25  LEU A HB2  1 
ATOM   394  H  HB3  . LEU A 1 36  ? -10.796 11.398  79.453 1   36.759  ? 25  LEU A HB3  1 
ATOM   395  H  HG   . LEU A 1 36  ? -13.117 9.982   78.562 1   44.754  ? 25  LEU A HG   1 
ATOM   396  H  HD11 . LEU A 1 36  ? -12.184 8.913   80.49  1   46.331  ? 25  LEU A HD11 1 
ATOM   397  H  HD12 . LEU A 1 36  ? -13.565 9.598   80.865 1   46.351  ? 25  LEU A HD12 1 
ATOM   398  H  HD13 . LEU A 1 36  ? -12.198 10.298  81.264 1   46.332  ? 25  LEU A HD13 1 
ATOM   399  H  HD21 . LEU A 1 36  ? -13.512 12.232  78.595 1   50.013  ? 25  LEU A HD21 1 
ATOM   400  H  HD22 . LEU A 1 36  ? -12.721 12.426  79.956 1   50.025  ? 25  LEU A HD22 1 
ATOM   401  H  HD23 . LEU A 1 36  ? -14.133 11.71   79.955 1   50.162  ? 25  LEU A HD23 1 
ATOM   402  N  N    . PRO A 1 37  ? -9.596  13.405  77.425 1   39.509  ? 26  PRO A N    1 
ATOM   403  C  CA   . PRO A 1 37  ? -8.347  14.139  77.588 1   39.949  ? 26  PRO A CA   1 
ATOM   404  C  C    . PRO A 1 37  ? -7.678  13.786  78.936 1   36.894  ? 26  PRO A C    1 
ATOM   405  O  O    . PRO A 1 37  ? -8.349  13.516  79.926 1   35.344  ? 26  PRO A O    1 
ATOM   406  C  CB   . PRO A 1 37  ? -8.771  15.61   77.498 1   41.76   ? 26  PRO A CB   1 
ATOM   407  C  CG   . PRO A 1 37  ? -10.191 15.604  76.986 1   45.823  ? 26  PRO A CG   1 
ATOM   408  C  CD   . PRO A 1 37  ? -10.794 14.255  77.356 1   45.103  ? 26  PRO A CD   1 
ATOM   409  H  HA   . PRO A 1 37  ? -7.74   13.919  76.838 1   39.509  ? 26  PRO A HA   1 
ATOM   410  H  HB2  . PRO A 1 37  ? -8.723  16.042  78.383 1   42.201  ? 26  PRO A HB2  1 
ATOM   411  H  HB3  . PRO A 1 37  ? -8.181  16.104  76.88  1   42.227  ? 26  PRO A HB3  1 
ATOM   412  H  HG2  . PRO A 1 37  ? -10.705 16.33   77.396 1   44.704  ? 26  PRO A HG2  1 
ATOM   413  H  HG3  . PRO A 1 37  ? -10.204 15.727  76.013 1   44.704  ? 26  PRO A HG3  1 
ATOM   414  H  HD2  . PRO A 1 37  ? -11.256 14.295  78.223 1   43.86   ? 26  PRO A HD2  1 
ATOM   415  H  HD3  . PRO A 1 37  ? -11.416 13.947  76.662 1   43.734  ? 26  PRO A HD3  1 
ATOM   416  N  N    . VAL A 1 38  ? -6.375  13.598  78.884 1   29.953  ? 27  VAL A N    1 
ATOM   417  C  CA   . VAL A 1 38  ? -5.585  13.287  80.054 1   41.886  ? 27  VAL A CA   1 
ATOM   418  C  C    . VAL A 1 38  ? -5.442  14.535  80.906 1   41.124  ? 27  VAL A C    1 
ATOM   419  O  O    . VAL A 1 38  ? -5.279  15.65   80.394 1   37.614  ? 27  VAL A O    1 
ATOM   420  C  CB   . VAL A 1 38  ? -4.251  12.744  79.537 1   40.545  ? 27  VAL A CB   1 
ATOM   421  C  CG1  . VAL A 1 38  ? -3.229  12.512  80.61  1   40.375  ? 27  VAL A CG1  1 
ATOM   422  C  CG2  . VAL A 1 38  ? -4.449  11.386  78.897 1   43.71   ? 27  VAL A CG2  1 
ATOM   423  H  H    . VAL A 1 38  ? -5.95   13.672  78.077 1   34.252  ? 27  VAL A H    1 
ATOM   424  H  HA   . VAL A 1 38  ? -6.038  12.59   80.568 1   38.805  ? 27  VAL A HA   1 
ATOM   425  H  HB   . VAL A 1 38  ? -3.895  13.378  78.871 1   41.193  ? 27  VAL A HB   1 
ATOM   426  H  HG11 . VAL A 1 38  ? -3.602  11.929  81.293 1   40.453  ? 27  VAL A HG11 1 
ATOM   427  H  HG12 . VAL A 1 38  ? -2.979  13.361  81.012 1   40.442  ? 27  VAL A HG12 1 
ATOM   428  H  HG13 . VAL A 1 38  ? -2.44   12.095  80.226 1   40.466  ? 27  VAL A HG13 1 
ATOM   429  H  HG21 . VAL A 1 38  ? -3.594  11.043  78.588 1   42.712  ? 27  VAL A HG21 1 
ATOM   430  H  HG22 . VAL A 1 38  ? -5.055  11.467  78.143 1   42.508  ? 27  VAL A HG22 1 
ATOM   431  H  HG23 . VAL A 1 38  ? -4.826  10.772  79.55  1   42.682  ? 27  VAL A HG23 1 
ATOM   432  N  N    . GLY A 1 39  ? -5.49   14.328  82.216 1   37.471  ? 28  GLY A N    1 
ATOM   433  C  CA   . GLY A 1 39  ? -5.238  15.39   83.188 1   35.874  ? 28  GLY A CA   1 
ATOM   434  C  C    . GLY A 1 39  ? -6.334  15.395  84.233 1   37.714  ? 28  GLY A C    1 
ATOM   435  O  O    . GLY A 1 39  ? -7.365  14.775  84.054 1   39.211  ? 28  GLY A O    1 
ATOM   436  H  H    . GLY A 1 39  ? -5.687  13.492  82.528 1   37.971  ? 28  GLY A H    1 
ATOM   437  H  HA2  . GLY A 1 39  ? -4.364  15.24   83.619 1   36.659  ? 28  GLY A HA2  1 
ATOM   438  H  HA3  . GLY A 1 39  ? -5.21   16.262  82.729 1   36.683  ? 28  GLY A HA3  1 
ATOM   439  N  N    . GLY A 1 40  ? -6.137  16.096  85.347 1   44.066  ? 29  GLY A N    1 
ATOM   440  C  CA   . GLY A 1 40  ? -7.165  16.116  86.369 1   44.887  ? 29  GLY A CA   1 
ATOM   441  C  C    . GLY A 1 40  ? -7.248  14.703  86.936 1   39.831  ? 29  GLY A C    1 
ATOM   442  O  O    . GLY A 1 40  ? -6.241  14.101  87.182 1   35.909  ? 29  GLY A O    1 
ATOM   443  H  H    . GLY A 1 40  ? -5.361  16.562  85.475 1   42.584  ? 29  GLY A H    1 
ATOM   444  H  HA2  . GLY A 1 40  ? -6.923  16.758  87.077 1   43.496  ? 29  GLY A HA2  1 
ATOM   445  H  HA3  . GLY A 1 40  ? -8.028  16.385  85.975 1   43.382  ? 29  GLY A HA3  1 
ATOM   446  N  N    . TRP A 1 41  ? -8.413  14.092  86.895 1   32.065  ? 30  TRP A N    1 
ATOM   447  C  CA   . TRP A 1 41  ? -8.602  12.766  87.434 1   29.561  ? 30  TRP A CA   1 
ATOM   448  C  C    . TRP A 1 41  ? -8.473  11.651  86.401 1   26.012  ? 30  TRP A C    1 
ATOM   449  O  O    . TRP A 1 41  ? -8.623  10.517  86.772 1   32.836  ? 30  TRP A O    1 
ATOM   450  C  CB   . TRP A 1 41  ? -9.966  12.666  88.121 1   31.62   ? 30  TRP A CB   1 
ATOM   451  C  CG   . TRP A 1 41  ? -10.159 13.68   89.187 1   34.373  ? 30  TRP A CG   1 
ATOM   452  C  CD1  . TRP A 1 41  ? -11.022 14.746  89.115 1   34.468  ? 30  TRP A CD1  1 
ATOM   453  C  CD2  . TRP A 1 41  ? -9.476  13.767  90.448 1   38.797  ? 30  TRP A CD2  1 
ATOM   454  N  NE1  . TRP A 1 41  ? -10.898 15.474  90.258 1   33.476  ? 30  TRP A NE1  1 
ATOM   455  C  CE2  . TRP A 1 41  ? -10.001 14.907  91.103 1   35.047  ? 30  TRP A CE2  1 
ATOM   456  C  CE3  . TRP A 1 41  ? -8.508  13.003  91.097 1   36.533  ? 30  TRP A CE3  1 
ATOM   457  C  CZ2  . TRP A 1 41  ? -9.587  15.314  92.368 1   38.359  ? 30  TRP A CZ2  1 
ATOM   458  C  CZ3  . TRP A 1 41  ? -8.135  13.37   92.378 1   36.066  ? 30  TRP A CZ3  1 
ATOM   459  C  CH2  . TRP A 1 41  ? -8.653  14.514  92.998 1   39.477  ? 30  TRP A CH2  1 
ATOM   460  H  H    . TRP A 1 41  ? -9.128  14.515  86.513 1   33.284  ? 30  TRP A H    1 
ATOM   461  H  HA   . TRP A 1 41  ? -7.906  12.618  88.13  1   29.785  ? 30  TRP A HA   1 
ATOM   462  H  HB2  . TRP A 1 41  ? -10.667 12.778  87.444 1   31.753  ? 30  TRP A HB2  1 
ATOM   463  H  HB3  . TRP A 1 41  ? -10.056 11.772  88.513 1   31.732  ? 30  TRP A HB3  1 
ATOM   464  H  HD1  . TRP A 1 41  ? -11.596 14.961  88.396 1   34.236  ? 30  TRP A HD1  1 
ATOM   465  H  HE1  . TRP A 1 41  ? -11.369 16.187  90.442 1   34.117  ? 30  TRP A HE1  1 
ATOM   466  H  HE3  . TRP A 1 41  ? -8.168  12.219  90.699 1   36.921  ? 30  TRP A HE3  1 
ATOM   467  H  HZ2  . TRP A 1 41  ? -9.951  16.076  92.786 1   37.783  ? 30  TRP A HZ2  1 
ATOM   468  H  HZ3  . TRP A 1 41  ? -7.476  12.868  92.826 1   36.945  ? 30  TRP A HZ3  1 
ATOM   469  H  HH2  . TRP A 1 41  ? -8.344  14.755  93.853 1   38.346  ? 30  TRP A HH2  1 
ATOM   470  N  N    . VAL A 1 42  ? -8.192  11.965  85.144 1   30.966  ? 31  VAL A N    1 
ATOM   471  C  CA   . VAL A 1 42  ? -7.892  11.04   84.076 1   26.863  ? 31  VAL A CA   1 
ATOM   472  C  C    . VAL A 1 42  ? -6.4    10.785  84.005 1   30.696  ? 31  VAL A C    1 
ATOM   473  O  O    . VAL A 1 42  ? -5.592  11.546  83.486 1   29.514  ? 31  VAL A O    1 
ATOM   474  C  CB   . VAL A 1 42  ? -8.411  11.596  82.746 1   28.596  ? 31  VAL A CB   1 
ATOM   475  C  CG1  . VAL A 1 42  ? -8.259  10.545  81.69  1   32.975  ? 31  VAL A CG1  1 
ATOM   476  C  CG2  . VAL A 1 42  ? -9.856  12.051  82.9   1   30.931  ? 31  VAL A CG2  1 
ATOM   477  H  H    . VAL A 1 42  ? -8.18   12.854  84.935 1   28.855  ? 31  VAL A H    1 
ATOM   478  H  HA   . VAL A 1 42  ? -8.35   10.197  84.258 1   28.69   ? 31  VAL A HA   1 
ATOM   479  H  HB   . VAL A 1 42  ? -7.855  12.375  82.507 1   29.466  ? 31  VAL A HB   1 
ATOM   480  H  HG11 . VAL A 1 42  ? -8.611  9.701   82.018 1   31.542  ? 31  VAL A HG11 1 
ATOM   481  H  HG12 . VAL A 1 42  ? -7.319  10.439  81.468 1   31.578  ? 31  VAL A HG12 1 
ATOM   482  H  HG13 . VAL A 1 42  ? -8.749  10.811  80.894 1   31.573  ? 31  VAL A HG13 1 
ATOM   483  H  HG21 . VAL A 1 42  ? -10.266 12.135  82.023 1   30.241  ? 31  VAL A HG21 1 
ATOM   484  H  HG22 . VAL A 1 42  ? -9.88   12.913  83.349 1   30.218  ? 31  VAL A HG22 1 
ATOM   485  H  HG23 . VAL A 1 42  ? -10.348 11.399  83.426 1   30.207  ? 31  VAL A HG23 1 
ATOM   486  N  N    . GLN A 1 43  ? -6.084  9.588   84.442 1   30.178  ? 32  GLN A N    1 
ATOM   487  C  CA   . GLN A 1 43  ? -4.763  9.065   84.41  1   25.593  ? 32  GLN A CA   1 
ATOM   488  C  C    . GLN A 1 43  ? -4.343  8.856   82.977 1   32.571  ? 32  GLN A C    1 
ATOM   489  O  O    . GLN A 1 43  ? -5.075  8.322   82.163 1   29.801  ? 32  GLN A O    1 
ATOM   490  C  CB   . GLN A 1 43  ? -4.859  7.739   85.174 1   25.356  ? 32  GLN A CB   1 
ATOM   491  C  CG   . GLN A 1 43  ? -3.486  7.09    85.365 1   28.698  ? 32  GLN A CG   1 
ATOM   492  C  CD   . GLN A 1 43  ? -3.571  5.728   86.029 1   32.577  ? 32  GLN A CD   1 
ATOM   493  O  OE1  . GLN A 1 43  ? -4.572  5.312   86.615 1   31.684  ? 32  GLN A OE1  1 
ATOM   494  N  NE2  . GLN A 1 43  ? -2.471  5.027   85.945 1   33.176  ? 32  GLN A NE2  1 
ATOM   495  H  H    . GLN A 1 43  ? -6.748  9.061   84.786 1   29.059  ? 32  GLN A H    1 
ATOM   496  H  HA   . GLN A 1 43  ? -4.156  9.698   84.865 1   27.623  ? 32  GLN A HA   1 
ATOM   497  H  HB2  . GLN A 1 43  ? -5.267  7.895   86.048 1   26.181  ? 32  GLN A HB2  1 
ATOM   498  H  HB3  . GLN A 1 43  ? -5.438  7.124   84.677 1   26.161  ? 32  GLN A HB3  1 
ATOM   499  H  HG2  . GLN A 1 43  ? -3.049  6.989   84.494 1   28.751  ? 32  GLN A HG2  1 
ATOM   500  H  HG3  . GLN A 1 43  ? -2.924  7.677   85.914 1   28.735  ? 32  GLN A HG3  1 
ATOM   501  H  HE21 . GLN A 1 43  ? -2.505  4.181   85.683 1   32.983  ? 32  GLN A HE21 1 
ATOM   502  H  HE22 . GLN A 1 43  ? -1.693  5.399   86.152 1   32.959  ? 32  GLN A HE22 1 
ATOM   503  N  N    . PRO A 1 44  ? -3.075  9.125   82.647 1   29.172  ? 33  PRO A N    1 
ATOM   504  C  CA   . PRO A 1 44  ? -2.562  8.838   81.303 1   28.061  ? 33  PRO A CA   1 
ATOM   505  C  C    . PRO A 1 44  ? -2.677  7.355   81.017 1   32.68   ? 33  PRO A C    1 
ATOM   506  O  O    . PRO A 1 44  ? -2.579  6.608   81.959 1   28.779  ? 33  PRO A O    1 
ATOM   507  C  CB   . PRO A 1 44  ? -1.108  9.279   81.397 1   28.77   ? 33  PRO A CB   1 
ATOM   508  C  CG   . PRO A 1 44  ? -0.813  9.278   82.849 1   30.068  ? 33  PRO A CG   1 
ATOM   509  C  CD   . PRO A 1 44  ? -2.101  9.754   83.524 1   27.529  ? 33  PRO A CD   1 
ATOM   510  H  HA   . PRO A 1 44  ? -3.046  9.373   80.626 1   29.226  ? 33  PRO A HA   1 
ATOM   511  H  HB2  . PRO A 1 44  ? -0.519  8.651   80.919 1   28.932  ? 33  PRO A HB2  1 
ATOM   512  H  HB3  . PRO A 1 44  ? -0.99   10.181  81.015 1   28.909  ? 33  PRO A HB3  1 
ATOM   513  H  HG2  . PRO A 1 44  ? -0.576  8.377   83.154 1   29.183  ? 33  PRO A HG2  1 
ATOM   514  H  HG3  . PRO A 1 44  ? -0.071  9.885   83.053 1   29.183  ? 33  PRO A HG3  1 
ATOM   515  H  HD2  . PRO A 1 44  ? -2.164  9.42    84.445 1   28.431  ? 33  PRO A HD2  1 
ATOM   516  H  HD3  . PRO A 1 44  ? -2.177  10.734  83.51  1   28.448  ? 33  PRO A HD3  1 
ATOM   517  N  N    . PRO A 1 45  ? -2.947  6.887   79.766 1   31.07   ? 34  PRO A N    1 
ATOM   518  C  CA   . PRO A 1 45  ? -3.078  5.451   79.486 1   36.442  ? 34  PRO A CA   1 
ATOM   519  C  C    . PRO A 1 45  ? -1.666  4.901   79.46  1   36.683  ? 34  PRO A C    1 
ATOM   520  O  O    . PRO A 1 45  ? -0.687  5.631   79.303 1   36.548  ? 34  PRO A O    1 
ATOM   521  C  CB   . PRO A 1 45  ? -3.788  5.291   78.135 1   35.732  ? 34  PRO A CB   1 
ATOM   522  C  CG   . PRO A 1 45  ? -3.327  6.612   77.451 1   37.91   ? 34  PRO A CG   1 
ATOM   523  C  CD   . PRO A 1 45  ? -3.16   7.693   78.571 1   35.29   ? 34  PRO A CD   1 
ATOM   524  H  HA   . PRO A 1 45  ? -3.606  5.016   80.198 1   35.325  ? 34  PRO A HA   1 
ATOM   525  H  HB2  . PRO A 1 45  ? -3.466  4.497   77.647 1   36.359  ? 34  PRO A HB2  1 
ATOM   526  H  HB3  . PRO A 1 45  ? -4.768  5.259   78.242 1   36.358  ? 34  PRO A HB3  1 
ATOM   527  H  HG2  . PRO A 1 45  ? -2.477  6.474   76.985 1   36.826  ? 34  PRO A HG2  1 
ATOM   528  H  HG3  . PRO A 1 45  ? -3.993  6.904   76.795 1   36.825  ? 34  PRO A HG3  1 
ATOM   529  H  HD2  . PRO A 1 45  ? -2.387  8.273   78.39  1   34.775  ? 34  PRO A HD2  1 
ATOM   530  H  HD3  . PRO A 1 45  ? -3.968  8.245   78.654 1   34.775  ? 34  PRO A HD3  1 
ATOM   531  N  N    . ALA A 1 46  ? -1.603  3.649   79.873 1   44.914  ? 35  ALA A N    1 
ATOM   532  C  CA   . ALA A 1 46  ? -0.362  2.936   80.06  1   57.513  ? 35  ALA A CA   1 
ATOM   533  C  C    . ALA A 1 46  ? 0.126   2.568   78.666 1   59.522  ? 35  ALA A C    1 
ATOM   534  O  O    . ALA A 1 46  ? 1.321   2.693   78.454 1   52.385  ? 35  ALA A O    1 
ATOM   535  C  CB   . ALA A 1 46  ? -0.566  1.745   81.012 1   66.704  ? 35  ALA A CB   1 
ATOM   536  H  H    . ALA A 1 46  ? -2.383  3.205   80.044 1   45.249  ? 35  ALA A H    1 
ATOM   537  H  HA   . ALA A 1 46  ? 0.299   3.563   80.465 1   56.324  ? 35  ALA A HA   1 
ATOM   538  H  HB1  . ALA A 1 46  ? -0.878  2.066   81.875 1   63.878  ? 35  ALA A HB1  1 
ATOM   539  H  HB2  . ALA A 1 46  ? -1.225  1.136   80.639 1   63.878  ? 35  ALA A HB2  1 
ATOM   540  H  HB3  . ALA A 1 46  ? 0.276   1.273   81.131 1   63.878  ? 35  ALA A HB3  1 
ATOM   541  N  N    . GLY A 1 47  ? -0.793  2.277   77.712 1   49.898  ? 36  GLY A N    1 
ATOM   542  C  CA   . GLY A 1 47  ? -0.392  2.2     76.321 1   55.04   ? 36  GLY A CA   1 
ATOM   543  C  C    . GLY A 1 47  ? -0.979  3.287   75.411 1   60.883  ? 36  GLY A C    1 
ATOM   544  O  O    . GLY A 1 47  ? -0.796  4.503   75.612 1   51.279  ? 36  GLY A O    1 
ATOM   545  H  H    . GLY A 1 47  ? -1.664  2.117   77.939 1   53.14   ? 36  GLY A H    1 
ATOM   546  H  HA2  . GLY A 1 47  ? 0.591   2.248   76.273 1   55.033  ? 36  GLY A HA2  1 
ATOM   547  H  HA3  . GLY A 1 47  ? -0.655  1.315   75.976 1   55.183  ? 36  GLY A HA3  1 
ATOM   548  N  N    . GLY A 1 48  ? -1.578  2.794   74.313 1   70.393  ? 37  GLY A N    1 
ATOM   549  C  CA   . GLY A 1 48  ? -2.127  3.615   73.246 1   83.894  ? 37  GLY A CA   1 
ATOM   550  C  C    . GLY A 1 48  ? -2.959  4.737   73.851 1   79.213  ? 37  GLY A C    1 
ATOM   551  O  O    . GLY A 1 48  ? -3.713  4.492   74.807 1   58.553  ? 37  GLY A O    1 
ATOM   552  H  H    . GLY A 1 48  ? -1.649  1.887   74.228 1   70.481  ? 37  GLY A H    1 
ATOM   553  H  HA2  . GLY A 1 48  ? -1.392  3.989   72.707 1   79.1    ? 37  GLY A HA2  1 
ATOM   554  H  HA3  . GLY A 1 48  ? -2.69   3.057   72.658 1   79.379  ? 37  GLY A HA3  1 
ATOM   555  N  N    . GLY A 1 49  ? -2.772  5.95    73.317 1   60.872  ? 38  GLY A N    1 
ATOM   556  C  CA   . GLY A 1 49  ? -3.652  7.025   73.671 1   59.392  ? 38  GLY A CA   1 
ATOM   557  C  C    . GLY A 1 49  ? -4.127  7.878   72.499 1   67.646  ? 38  GLY A C    1 
ATOM   558  O  O    . GLY A 1 49  ? -3.981  9.09    72.638 1   51.909  ? 38  GLY A O    1 
ATOM   559  H  H    . GLY A 1 49  ? -2.088  6.102   72.729 1   64.694  ? 38  GLY A H    1 
ATOM   560  H  HA2  . GLY A 1 49  ? -4.441  6.648   74.124 1   61.384  ? 38  GLY A HA2  1 
ATOM   561  H  HA3  . GLY A 1 49  ? -3.189  7.605   74.321 1   61.419  ? 38  GLY A HA3  1 
ATOM   562  N  N    . HIS A 1 50  ? -4.819  7.293   71.476 1   57.591  ? 39  HIS A N    1 
ATOM   563  C  CA   . HIS A 1 50  ? -5.344  8.057   70.345 1   63.539  ? 39  HIS A CA   1 
ATOM   564  C  C    . HIS A 1 50  ? -6.863  8.155   70.354 1   57.828  ? 39  HIS A C    1 
ATOM   565  O  O    . HIS A 1 50  ? -7.535  7.157   70.084 1   48.165  ? 39  HIS A O    1 
ATOM   566  C  CB   . HIS A 1 50  ? -5.026  7.45    68.97  1   71.54   ? 39  HIS A CB   1 
ATOM   567  C  CG   . HIS A 1 50  ? -3.574  7.425   68.66  1   90.581  ? 39  HIS A CG   1 
ATOM   568  N  ND1  . HIS A 1 50  ? -2.964  8.397   67.895 1   89.657  ? 39  HIS A ND1  1 
ATOM   569  C  CD2  . HIS A 1 50  ? -2.614  6.538   69.018 1   81.248  ? 39  HIS A CD2  1 
ATOM   570  C  CE1  . HIS A 1 50  ? -1.677  8.117   67.834 1   91.693  ? 39  HIS A CE1  1 
ATOM   571  N  NE2  . HIS A 1 50  ? -1.443  7.009   68.524 1   76.062  ? 39  HIS A NE2  1 
ATOM   572  H  H    . HIS A 1 50  ? -4.96   6.39    71.497 1   61.182  ? 39  HIS A H    1 
ATOM   573  H  HA   . HIS A 1 50  ? -4.97   8.971   70.381 1   62.394  ? 39  HIS A HA   1 
ATOM   574  H  HB2  . HIS A 1 50  ? -5.372  6.532   68.942 1   73.193  ? 39  HIS A HB2  1 
ATOM   575  H  HB3  . HIS A 1 50  ? -5.49   7.971   68.278 1   73.45   ? 39  HIS A HB3  1 
ATOM   576  H  HD1  . HIS A 1 50  ? -3.312  9.096   67.589 0   87.28   ? 39  HIS A HD1  1 
ATOM   577  H  HD2  . HIS A 1 50  ? -2.719  5.78    69.557 1   82.064  ? 39  HIS A HD2  1 
ATOM   578  H  HE1  . HIS A 1 50  ? -1.033  8.623   67.37  1   87.249  ? 39  HIS A HE1  1 
ATOM   579  H  HE2  . HIS A 1 50  ? -0.651  6.568   68.637 0   75.57   ? 39  HIS A HE2  1 
ATOM   580  N  N    . ALA A 1 51  ? -7.363  9.404   70.497 1   49.522  ? 40  ALA A N    1 
ATOM   581  C  CA   . ALA A 1 51  ? -8.799  9.67    70.419 1   53.397  ? 40  ALA A CA   1 
ATOM   582  C  C    . ALA A 1 51  ? -9.342  9.172   69.07  1   69.475  ? 40  ALA A C    1 
ATOM   583  O  O    . ALA A 1 51  ? -10.123 8.211   69.001 1   70.65   ? 40  ALA A O    1 
ATOM   584  C  CB   . ALA A 1 51  ? -9.127  11.131  70.662 1   47.036  ? 40  ALA A CB   1 
ATOM   585  H  H    . ALA A 1 51  ? -6.794  10.103  70.65  1   52.384  ? 40  ALA A H    1 
ATOM   586  H  HA   . ALA A 1 51  ? -9.24   9.131   71.131 1   53.873  ? 40  ALA A HA   1 
ATOM   587  H  HB1  . ALA A 1 51  ? -8.899  11.37   71.576 1   48.776  ? 40  ALA A HB1  1 
ATOM   588  H  HB2  . ALA A 1 51  ? -8.619  11.688  70.048 1   48.819  ? 40  ALA A HB2  1 
ATOM   589  H  HB3  . ALA A 1 51  ? -10.077 11.282  70.519 1   48.82   ? 40  ALA A HB3  1 
ATOM   590  N  N    . GLU A 1 52  ? -8.853  9.747   67.963 1   54.492  ? 41  GLU A N    1 
ATOM   591  C  CA   . GLU A 1 52  ? -9.395  9.308   66.684 1   54.359  ? 41  GLU A CA   1 
ATOM   592  C  C    . GLU A 1 52  ? -8.302  8.545   65.957 1   43.554  ? 41  GLU A C    1 
ATOM   593  O  O    . GLU A 1 52  ? -7.424  9.167   65.429 1   54.498  ? 41  GLU A O    1 
ATOM   594  C  CB   . GLU A 1 52  ? -9.904  10.583  66.011 1   54.2    ? 41  GLU A CB   1 
ATOM   595  C  CG   . GLU A 1 52  ? -10.702 10.295  64.738 1   60.633  ? 41  GLU A CG   1 
ATOM   596  C  CD   . GLU A 1 52  ? -9.779  10.063  63.537 1   63.94   ? 41  GLU A CD   1 
ATOM   597  O  OE1  . GLU A 1 52  ? -9.11   11.112  63.134 1   43.056  ? 41  GLU A OE1  1 
ATOM   598  O  OE2  . GLU A 1 52  ? -9.691  8.845   63.09  1   50.943  ? 41  GLU A OE2  1 
ATOM   599  H  H    . GLU A 1 52  ? -8.205  10.39   67.998 1   57.707  ? 41  GLU A H    1 
ATOM   600  H  HA   . GLU A 1 52  ? -10.158 8.701   66.846 1   52.454  ? 41  GLU A HA   1 
ATOM   601  H  HB2  . GLU A 1 52  ? -10.475 11.067  66.643 1   55.618  ? 41  GLU A HB2  1 
ATOM   602  H  HB3  . GLU A 1 52  ? -9.139  11.157  65.798 1   55.589  ? 41  GLU A HB3  1 
ATOM   603  H  HG2  . GLU A 1 52  ? -11.256 9.497   64.871 1   59.752  ? 41  GLU A HG2  1 
ATOM   604  H  HG3  . GLU A 1 52  ? -11.294 11.053  64.544 1   59.816  ? 41  GLU A HG3  1 
ATOM   605  N  N    . SER A 1 53  ? -8.321  7.22    66.004 1   48.584  ? 42  SER A N    1 
ATOM   606  C  CA   . SER A 1 53  ? -7.12   6.456   65.762 1   48.471  ? 42  SER A CA   1 
ATOM   607  C  C    . SER A 1 53  ? -7.063  6.051   64.296 1   39.047  ? 42  SER A C    1 
ATOM   608  O  O    . SER A 1 53  ? -8.076  5.723   63.729 1   40.117  ? 42  SER A O    1 
ATOM   609  C  CB   . SER A 1 53  ? -7.069  5.238   66.663 1   55.572  ? 42  SER A CB   1 
ATOM   610  O  OG   . SER A 1 53  ? -5.961  4.402   66.372 1   55.536  ? 42  SER A OG   1 
ATOM   611  H  H    . SER A 1 53  ? -9.1    6.779   66.188 1   47.441  ? 42  SER A H    1 
ATOM   612  H  HA   . SER A 1 53  ? -6.339  7.029   65.963 1   47.639  ? 42  SER A HA   1 
ATOM   613  H  HB2  . SER A 1 53  ? -7.015  5.531   67.593 1   53.983  ? 42  SER A HB2  1 
ATOM   614  H  HB3  . SER A 1 53  ? -7.893  4.727   66.557 1   53.893  ? 42  SER A HB3  1 
ATOM   615  H  HG   . SER A 1 53  ? -5.997  3.705   66.88  0   56.58   ? 42  SER A HG   1 
ATOM   616  N  N    . PRO A 1 54  ? -5.883  6.045   63.652 1   31.573  ? 43  PRO A N    1 
ATOM   617  C  CA   . PRO A 1 54  ? -5.765  5.574   62.273 1   35.177  ? 43  PRO A CA   1 
ATOM   618  C  C    . PRO A 1 54  ? -5.947  4.055   62.153 1   33.895  ? 43  PRO A C    1 
ATOM   619  O  O    . PRO A 1 54  ? -6.225  3.576   61.073 1   35.496  ? 43  PRO A O    1 
ATOM   620  C  CB   . PRO A 1 54  ? -4.303  5.968   61.914 1   36.41   ? 43  PRO A CB   1 
ATOM   621  C  CG   . PRO A 1 54  ? -3.538  5.937   63.261 1   35.653  ? 43  PRO A CG   1 
ATOM   622  C  CD   . PRO A 1 54  ? -4.577  6.48    64.211 1   36.584  ? 43  PRO A CD   1 
ATOM   623  H  HA   . PRO A 1 54  ? -6.405  6.052   61.688 1   34.458  ? 43  PRO A HA   1 
ATOM   624  H  HB2  . PRO A 1 54  ? -3.912  5.327   61.275 1   35.953  ? 43  PRO A HB2  1 
ATOM   625  H  HB3  . PRO A 1 54  ? -4.272  6.87    61.515 1   35.963  ? 43  PRO A HB3  1 
ATOM   626  H  HG2  . PRO A 1 54  ? -3.275  5.025   63.503 1   36.029  ? 43  PRO A HG2  1 
ATOM   627  H  HG3  . PRO A 1 54  ? -2.744  6.511   63.235 1   36.029  ? 43  PRO A HG3  1 
ATOM   628  H  HD2  . PRO A 1 54  ? -4.442  6.115   65.113 1   35.381  ? 43  PRO A HD2  1 
ATOM   629  H  HD3  . PRO A 1 54  ? -4.527  7.46    64.258 1   35.203  ? 43  PRO A HD3  1 
ATOM   630  N  N    . GLU A 1 55  ? -5.858  3.326   63.249 1   35.321  ? 44  GLU A N    1 
ATOM   631  C  CA   . GLU A 1 55  ? -5.758  1.863   63.211 1   39.724  ? 44  GLU A CA   1 
ATOM   632  C  C    . GLU A 1 55  ? -6.999  1.226   62.616 1   37.88   ? 44  GLU A C    1 
ATOM   633  O  O    . GLU A 1 55  ? -6.894  0.266   61.874 1   40.825  ? 44  GLU A O    1 
ATOM   634  C  CB   . GLU A 1 55  ? -5.447  1.205   64.564 1   45.548  ? 44  GLU A CB   1 
ATOM   635  C  CG   . GLU A 1 55  ? -3.938  1.049   64.809 1   62.486  ? 44  GLU A CG   1 
ATOM   636  C  CD   . GLU A 1 55  ? -2.969  0.777   63.626 1   69.931  ? 44  GLU A CD   1 
ATOM   637  O  OE1  . GLU A 1 55  ? -2.884  -0.358  63.023 1   65.606  ? 44  GLU A OE1  1 
ATOM   638  O  OE2  . GLU A 1 55  ? -2.26   1.771   63.296 1   84.166  ? 44  GLU A OE2  1 
ATOM   639  H  H    . GLU A 1 55  ? -5.85   3.739   64.064 1   35.967  ? 44  GLU A H    1 
ATOM   640  H  HA   . GLU A 1 55  ? -5.007  1.642   62.606 1   39.687  ? 44  GLU A HA   1 
ATOM   641  H  HB2  . GLU A 1 55  ? -5.837  1.748   65.28  1   47.35   ? 44  GLU A HB2  1 
ATOM   642  H  HB3  . GLU A 1 55  ? -5.869  0.32    64.595 1   47.377  ? 44  GLU A HB3  1 
ATOM   643  H  HG2  . GLU A 1 55  ? -3.625  1.861   65.261 1   59.729  ? 44  GLU A HG2  1 
ATOM   644  H  HG3  . GLU A 1 55  ? -3.816  0.321   65.456 1   59.621  ? 44  GLU A HG3  1 
ATOM   645  N  N    . THR A 1 56  ? -8.183  1.752   62.916 1   33.855  ? 45  THR A N    1 
ATOM   646  C  CA   . THR A 1 56  ? -9.381  1.148   62.361 1   38.947  ? 45  THR A CA   1 
ATOM   647  C  C    . THR A 1 56  ? -9.371  1.226   60.836 1   42.044  ? 45  THR A C    1 
ATOM   648  O  O    . THR A 1 56  ? -9.712  0.233   60.168 1   36.916  ? 45  THR A O    1 
ATOM   649  C  CB   . THR A 1 56  ? -10.656 1.803   62.903 1   46.697  ? 45  THR A CB   1 
ATOM   650  O  OG1  . THR A 1 56  ? -10.492 3.212   62.688 1   54.925  ? 45  THR A OG1  1 
ATOM   651  C  CG2  . THR A 1 56  ? -10.811 1.537   64.388 1   50.177  ? 45  THR A CG2  1 
ATOM   652  H  H    . THR A 1 56  ? -8.251  2.48    63.464 1   36.114  ? 45  THR A H    1 
ATOM   653  H  HA   . THR A 1 56  ? -9.392  0.201   62.622 1   39.733  ? 45  THR A HA   1 
ATOM   654  H  HB   . THR A 1 56  ? -11.449 1.479   62.412 1   47.249  ? 45  THR A HB   1 
ATOM   655  H  HG1  . THR A 1 56  ? -9.795  3.47    63.111 0   54.34   ? 45  THR A HG1  1 
ATOM   656  H  HG21 . THR A 1 56  ? -11.345 2.243   64.79  1   49.013  ? 45  THR A HG21 1 
ATOM   657  H  HG22 . THR A 1 56  ? -9.936  1.513   64.811 1   48.804  ? 45  THR A HG22 1 
ATOM   658  H  HG23 . THR A 1 56  ? -11.257 0.683   64.518 1   48.88   ? 45  THR A HG23 1 
ATOM   659  N  N    . LYS A 1 57  ? -9.022  2.407   60.318 1   32.179  ? 46  LYS A N    1 
ATOM   660  C  CA   . LYS A 1 57  ? -8.99   2.654   58.886 1   32.215  ? 46  LYS A CA   1 
ATOM   661  C  C    . LYS A 1 57  ? -7.888  1.836   58.222 1   32.211  ? 46  LYS A C    1 
ATOM   662  O  O    . LYS A 1 57  ? -8.098  1.264   57.151 1   35.466  ? 46  LYS A O    1 
ATOM   663  C  CB   . LYS A 1 57  ? -8.846  4.16    58.604 1   36.014  ? 46  LYS A CB   1 
ATOM   664  C  CG   . LYS A 1 57  ? -10.067 5.069   58.853 1   48.727  ? 46  LYS A CG   1 
ATOM   665  C  CD   . LYS A 1 57  ? -10.175 5.641   60.277 1   59.731  ? 46  LYS A CD   1 
ATOM   666  C  CE   . LYS A 1 57  ? -11.209 6.737   60.31  1   65.792  ? 46  LYS A CE   1 
ATOM   667  N  NZ   . LYS A 1 57  ? -11.53  7.29    61.634 1   86.36   ? 46  LYS A NZ   1 
ATOM   668  H  H    . LYS A 1 57  ? -8.8    3.09    60.883 1   34.376  ? 46  LYS A H    1 
ATOM   669  H  HA   . LYS A 1 57  ? -9.858  2.36    58.509 1   32.93   ? 46  LYS A HA   1 
ATOM   670  H  HB2  . LYS A 1 57  ? -8.103  4.499   59.146 1   37.701  ? 46  LYS A HB2  1 
ATOM   671  H  HB3  . LYS A 1 57  ? -8.588  4.263   57.663 1   37.595  ? 46  LYS A HB3  1 
ATOM   672  H  HG2  . LYS A 1 57  ? -10.031 5.816   58.216 1   47.73   ? 46  LYS A HG2  1 
ATOM   673  H  HG3  . LYS A 1 57  ? -10.88  4.555   58.658 1   47.648  ? 46  LYS A HG3  1 
ATOM   674  H  HD2  . LYS A 1 57  ? -10.436 4.928   60.898 1   58.247  ? 46  LYS A HD2  1 
ATOM   675  H  HD3  . LYS A 1 57  ? -9.306  6.002   60.556 1   57.94   ? 46  LYS A HD3  1 
ATOM   676  H  HE2  . LYS A 1 57  ? -10.897 7.464   59.743 1   68.277  ? 46  LYS A HE2  1 
ATOM   677  H  HE3  . LYS A 1 57  ? -12.031 6.395   59.918 1   68.049  ? 46  LYS A HE3  1 
ATOM   678  H  HZ1  . LYS A 1 57  ? -10.8   7.701   61.979 1   79.404  ? 46  LYS A HZ1  1 
ATOM   679  H  HZ2  . LYS A 1 57  ? -11.787 6.623   62.19  1   79.404  ? 46  LYS A HZ2  1 
ATOM   680  H  HZ3  . LYS A 1 57  ? -12.202 7.892   61.559 1   79.404  ? 46  LYS A HZ3  1 
ATOM   681  N  N    . ARG A 1 58  ? -6.7    1.764   58.866 1   28.323  ? 47  ARG A N    1 
ATOM   682  C  CA   . ARG A 1 58  ? -5.596  1.039   58.267 1   31.977  ? 47  ARG A CA   1 
ATOM   683  C  C    . ARG A 1 58  ? -5.902  -0.466  58.234 1   29.456  ? 47  ARG A C    1 
ATOM   684  O  O    . ARG A 1 58  ? -5.671  -1.126  57.217 1   33.013  ? 47  ARG A O    1 
ATOM   685  C  CB   . ARG A 1 58  ? -4.312  1.391   59.034 1   30.207  ? 47  ARG A CB   1 
ATOM   686  C  CG   . ARG A 1 58  ? -3.086  0.862   58.308 1   42.11   ? 47  ARG A CG   1 
ATOM   687  C  CD   . ARG A 1 58  ? -1.782  0.984   59.106 1   38.131  ? 47  ARG A CD   1 
ATOM   688  N  NE   . ARG A 1 58  ? -1.424  2.398   59.34  1   39.47   ? 47  ARG A NE   1 
ATOM   689  C  CZ   . ARG A 1 58  ? -0.7    3.069   58.417 1   31.821  ? 47  ARG A CZ   1 
ATOM   690  N  NH1  . ARG A 1 58  ? -0.516  2.51    57.226 1   36.849  ? 47  ARG A NH1  1 
ATOM   691  N  NH2  . ARG A 1 58  ? -0.232  4.273   58.648 1   35      ? 47  ARG A NH2  1 
ATOM   692  H  H    . ARG A 1 58  ? -6.584  2.173   59.675 1   30.042  ? 47  ARG A H    1 
ATOM   693  H  HA   . ARG A 1 58  ? -5.491  1.355   57.334 1   30.479  ? 47  ARG A HA   1 
ATOM   694  H  HB2  . ARG A 1 58  ? -4.24   2.366   59.123 1   33.022  ? 47  ARG A HB2  1 
ATOM   695  H  HB3  . ARG A 1 58  ? -4.35   1.003   59.933 1   33.022  ? 47  ARG A HB3  1 
ATOM   696  H  HG2  . ARG A 1 58  ? -3.229  -0.083  58.085 1   38.092  ? 47  ARG A HG2  1 
ATOM   697  H  HG3  . ARG A 1 58  ? -2.985  1.35    57.463 1   38.085  ? 47  ARG A HG3  1 
ATOM   698  H  HD2  . ARG A 1 58  ? -1.893  0.534   59.969 1   39.295  ? 47  ARG A HD2  1 
ATOM   699  H  HD3  . ARG A 1 58  ? -1.057  0.535   58.625 1   39.241  ? 47  ARG A HD3  1 
ATOM   700  H  HE   . ARG A 1 58  ? -1.68   2.796   60.072 1   37.174  ? 47  ARG A HE   1 
ATOM   701  H  HH11 . ARG A 1 58  ? -1.169  2.521   56.629 1   35.248  ? 47  ARG A HH11 1 
ATOM   702  H  HH12 . ARG A 1 58  ? 0.262   2.13    57.035 1   35.227  ? 47  ARG A HH12 1 
ATOM   703  H  HH21 . ARG A 1 58  ? -0.488  4.712   59.372 1   34.053  ? 47  ARG A HH21 1 
ATOM   704  H  HH22 . ARG A 1 58  ? 0.34    4.639   58.084 1   34.033  ? 47  ARG A HH22 1 
ATOM   705  N  N    . ARG A 1 59  ? -6.537  -0.959  59.299 1   29.174  ? 48  ARG A N    1 
ATOM   706  C  CA   . ARG A 1 59  ? -6.861  -2.367  59.414 1   31.966  ? 48  ARG A CA   1 
ATOM   707  C  C    . ARG A 1 59  ? -7.882  -2.74   58.348 1   29.117  ? 48  ARG A C    1 
ATOM   708  O  O    . ARG A 1 59  ? -7.861  -3.84   57.83  1   29.296  ? 48  ARG A O    1 
ATOM   709  C  CB   . ARG A 1 59  ? -7.365  -2.7    60.818 1   30.343  ? 48  ARG A CB   1 
ATOM   710  C  CG   . ARG A 1 59  ? -6.247  -2.764  61.846 1   32.26   ? 48  ARG A CG   1 
ATOM   711  C  CD   . ARG A 1 59  ? -6.764  -2.914  63.253 1   28.249  ? 48  ARG A CD   1 
ATOM   712  N  NE   . ARG A 1 59  ? -7.297  -4.249  63.568 1   27.654  ? 48  ARG A NE   1 
ATOM   713  C  CZ   . ARG A 1 59  ? -6.557  -5.28   63.923 1   26.587  ? 48  ARG A CZ   1 
ATOM   714  N  NH1  . ARG A 1 59  ? -5.246  -5.19   64     1   29.59   ? 48  ARG A NH1  1 
ATOM   715  N  NH2  . ARG A 1 59  ? -7.101  -6.463  64.089 1   28.481  ? 48  ARG A NH2  1 
ATOM   716  H  H    . ARG A 1 59  ? -6.771  -0.398  59.981 1   29.868  ? 48  ARG A H    1 
ATOM   717  H  HA   . ARG A 1 59  ? -6.033  -2.887  59.249 1   30.571  ? 48  ARG A HA   1 
ATOM   718  H  HB2  . ARG A 1 59  ? -8.018  -2.024  61.095 1   31.149  ? 48  ARG A HB2  1 
ATOM   719  H  HB3  . ARG A 1 59  ? -7.821  -3.568  60.794 1   31.099  ? 48  ARG A HB3  1 
ATOM   720  H  HG2  . ARG A 1 59  ? -5.663  -3.524  61.638 1   30.851  ? 48  ARG A HG2  1 
ATOM   721  H  HG3  . ARG A 1 59  ? -5.706  -1.947  61.789 1   30.905  ? 48  ARG A HG3  1 
ATOM   722  H  HD2  . ARG A 1 59  ? -6.046  -2.701  63.879 1   29.06   ? 48  ARG A HD2  1 
ATOM   723  H  HD3  . ARG A 1 59  ? -7.473  -2.252  63.389 1   29.008  ? 48  ARG A HD3  1 
ATOM   724  H  HE   . ARG A 1 59  ? -8.159  -4.367  63.517 1   27.541  ? 48  ARG A HE   1 
ATOM   725  H  HH11 . ARG A 1 59  ? -4.798  -4.659  63.456 1   28.667  ? 48  ARG A HH11 1 
ATOM   726  H  HH12 . ARG A 1 59  ? -4.816  -5.68   64.594 1   28.634  ? 48  ARG A HH12 1 
ATOM   727  H  HH21 . ARG A 1 59  ? -7.804  -6.695  63.605 1   27.884  ? 48  ARG A HH21 1 
ATOM   728  H  HH22 . ARG A 1 59  ? -6.763  -7.023  64.684 1   27.902  ? 48  ARG A HH22 1 
ATOM   729  N  N    . MET A 1 60  ? -8.769  -1.814  57.997 1   30.649  ? 49  MET A N    1 
ATOM   730  C  CA   . MET A 1 60  ? -9.738  -2.105  56.951 1   34.996  ? 49  MET A CA   1 
ATOM   731  C  C    . MET A 1 60  ? -8.973  -2.274  55.634 1   32.181  ? 49  MET A C    1 
ATOM   732  O  O    . MET A 1 60  ? -9.222  -3.172  54.864 1   29.416  ? 49  MET A O    1 
ATOM   733  C  CB   . MET A 1 60  ? -10.749 -0.958  56.836 1   30.555  ? 49  MET A CB   1 
ATOM   734  C  CG   . MET A 1 60  ? -11.728 -1.09   55.682 1   35.699  ? 49  MET A CG   1 
ATOM   735  S  SD   . MET A 1 60  ? -12.765 0.413   55.672 1   41.605  ? 49  MET A SD   1 
ATOM   736  C  CE   . MET A 1 60  ? -13.188 0.315   53.918 1   45.932  ? 49  MET A CE   1 
ATOM   737  H  H    . MET A 1 60  ? -8.783  -0.999  58.411 1   31.177  ? 49  MET A H    1 
ATOM   738  H  HA   . MET A 1 60  ? -10.208 -2.948  57.169 1   32.723  ? 49  MET A HA   1 
ATOM   739  H  HB2  . MET A 1 60  ? -11.255 -0.905  57.675 1   32.662  ? 49  MET A HB2  1 
ATOM   740  H  HB3  . MET A 1 60  ? -10.255 -0.117  56.735 1   32.697  ? 49  MET A HB3  1 
ATOM   741  H  HG2  . MET A 1 60  ? -11.249 -1.166  54.833 1   35.435  ? 49  MET A HG2  1 
ATOM   742  H  HG3  . MET A 1 60  ? -12.291 -1.881  55.802 1   35.402  ? 49  MET A HG3  1 
ATOM   743  H  HE1  . MET A 1 60  ? -13.788 1.048   53.688 1   44.785  ? 49  MET A HE1  1 
ATOM   744  H  HE2  . MET A 1 60  ? -12.375 0.379   53.384 1   44.74   ? 49  MET A HE2  1 
ATOM   745  H  HE3  . MET A 1 60  ? -13.63  -0.536  53.738 1   44.796  ? 49  MET A HE3  1 
ATOM   746  N  N    . LYS A 1 61  ? -8.074  -1.344  55.349 1   28.793  ? 50  LYS A N    1 
ATOM   747  C  CA   . LYS A 1 61  ? -7.306  -1.4    54.128 1   26.385  ? 50  LYS A CA   1 
ATOM   748  C  C    . LYS A 1 61  ? -6.434  -2.672  54.118 1   29.448  ? 50  LYS A C    1 
ATOM   749  O  O    . LYS A 1 61  ? -6.186  -3.224  53.069 1   28.009  ? 50  LYS A O    1 
ATOM   750  C  CB   . LYS A 1 61  ? -6.437  -0.171  53.912 1   30.309  ? 50  LYS A CB   1 
ATOM   751  C  CG   . LYS A 1 61  ? -5.472  -0.175  52.725 1   31.091  ? 50  LYS A CG   1 
ATOM   752  C  CD   . LYS A 1 61  ? -6.253  -0.305  51.446 1   33.125  ? 50  LYS A CD   1 
ATOM   753  C  CE   . LYS A 1 61  ? -5.507  -0.184  50.167 1   38.509  ? 50  LYS A CE   1 
ATOM   754  N  NZ   . LYS A 1 61  ? -4.273  -0.955  50.125 1   45.334  ? 50  LYS A NZ   1 
ATOM   755  H  H    . LYS A 1 61  ? -7.937  -0.649  55.927 1   29.043  ? 50  LYS A H    1 
ATOM   756  H  HA   . LYS A 1 61  ? -7.944  -1.457  53.372 1   28.17   ? 50  LYS A HA   1 
ATOM   757  H  HB2  . LYS A 1 61  ? -7.031  0.604   53.813 1   29.554  ? 50  LYS A HB2  1 
ATOM   758  H  HB3  . LYS A 1 61  ? -5.909  -0.029  54.726 1   29.533  ? 50  LYS A HB3  1 
ATOM   759  H  HG2  . LYS A 1 61  ? -4.963  0.665   52.718 1   31.379  ? 50  LYS A HG2  1 
ATOM   760  H  HG3  . LYS A 1 61  ? -4.846  -0.925  52.812 1   31.435  ? 50  LYS A HG3  1 
ATOM   761  H  HD2  . LYS A 1 61  ? -6.703  -1.177  51.454 1   33.699  ? 50  LYS A HD2  1 
ATOM   762  H  HD3  . LYS A 1 61  ? -6.96   0.375   51.455 1   33.776  ? 50  LYS A HD3  1 
ATOM   763  H  HE2  . LYS A 1 61  ? -6.082  -0.477  49.438 1   38.655  ? 50  LYS A HE2  1 
ATOM   764  H  HE3  . LYS A 1 61  ? -5.292  0.754   50.015 1   38.655  ? 50  LYS A HE3  1 
ATOM   765  H  HZ1  . LYS A 1 61  ? -4.372  -1.712  50.608 1   42.922  ? 50  LYS A HZ1  1 
ATOM   766  H  HZ2  . LYS A 1 61  ? -3.594  -0.467  50.474 1   43.063  ? 50  LYS A HZ2  1 
ATOM   767  H  HZ3  . LYS A 1 61  ? -4.075  -1.172  49.268 1   43.066  ? 50  LYS A HZ3  1 
ATOM   768  N  N    . ASN A 1 62  ? -5.846  -3.044  55.259 1   29.891  ? 51  ASN A N    1 
ATOM   769  C  CA   . ASN A 1 62  ? -4.983  -4.191  55.335 1   26.06   ? 51  ASN A CA   1 
ATOM   770  C  C    . ASN A 1 62  ? -5.78   -5.45   55.045 1   26.673  ? 51  ASN A C    1 
ATOM   771  O  O    . ASN A 1 62  ? -5.329  -6.34   54.358 1   29.137  ? 51  ASN A O    1 
ATOM   772  C  CB   . ASN A 1 62  ? -4.362  -4.307  56.711 1   30.298  ? 51  ASN A CB   1 
ATOM   773  C  CG   . ASN A 1 62  ? -3.397  -3.175  56.98  1   29.346  ? 51  ASN A CG   1 
ATOM   774  O  OD1  . ASN A 1 62  ? -2.946  -2.464  56.088 1   33.047  ? 51  ASN A OD1  1 
ATOM   775  N  ND2  . ASN A 1 62  ? -3.071  -2.998  58.231 1   28.836  ? 51  ASN A ND2  1 
ATOM   776  H  H    . ASN A 1 62  ? -5.994  -2.555  56.017 1   28.863  ? 51  ASN A H    1 
ATOM   777  H  HA   . ASN A 1 62  ? -4.261  -4.097  54.673 1   27.677  ? 51  ASN A HA   1 
ATOM   778  H  HB2  . ASN A 1 62  ? -5.069  -4.293  57.386 1   29.054  ? 51  ASN A HB2  1 
ATOM   779  H  HB3  . ASN A 1 62  ? -3.891  -5.16   56.783 1   29.045  ? 51  ASN A HB3  1 
ATOM   780  H  HD21 . ASN A 1 62  ? -2.228  -2.827  58.448 1   29      ? 51  ASN A HD21 1 
ATOM   781  H  HD22 . ASN A 1 62  ? -3.692  -3.047  58.862 1   29.014  ? 51  ASN A HD22 1 
ATOM   782  N  N    . LEU A 1 63  ? -7.014  -5.505  55.544 1   29.699  ? 52  LEU A N    1 
ATOM   783  C  CA   . LEU A 1 63  ? -7.858  -6.651  55.3   1   28.949  ? 52  LEU A CA   1 
ATOM   784  C  C    . LEU A 1 63  ? -8.303  -6.699  53.836 1   30.831  ? 52  LEU A C    1 
ATOM   785  O  O    . LEU A 1 63  ? -8.429  -7.776  53.247 1   25.52   ? 52  LEU A O    1 
ATOM   786  C  CB   . LEU A 1 63  ? -9.022  -6.632  56.291 1   32.501  ? 52  LEU A CB   1 
ATOM   787  C  CG   . LEU A 1 63  ? -10.068 -7.717  56.073 1   32.235  ? 52  LEU A CG   1 
ATOM   788  C  CD1  . LEU A 1 63  ? -9.442  -9.069  56.252 1   32.522  ? 52  LEU A CD1  1 
ATOM   789  C  CD2  . LEU A 1 63  ? -11.19  -7.539  57.035 1   33.932  ? 52  LEU A CD2  1 
ATOM   790  H  H    . LEU A 1 63  ? -7.333  -4.816  56.054 1   28.815  ? 52  LEU A H    1 
ATOM   791  H  HA   . LEU A 1 63  ? -7.315  -7.462  55.473 1   30.062  ? 52  LEU A HA   1 
ATOM   792  H  HB2  . LEU A 1 63  ? -8.656  -6.729  57.201 1   31.598  ? 52  LEU A HB2  1 
ATOM   793  H  HB3  . LEU A 1 63  ? -9.465  -5.755  56.231 1   31.578  ? 52  LEU A HB3  1 
ATOM   794  H  HG   . LEU A 1 63  ? -10.423 -7.642  55.15  1   32.672  ? 52  LEU A HG   1 
ATOM   795  H  HD11 . LEU A 1 63  ? -8.861  -9.262  55.496 1   32.403  ? 52  LEU A HD11 1 
ATOM   796  H  HD12 . LEU A 1 63  ? -10.138 -9.746  56.303 1   32.441  ? 52  LEU A HD12 1 
ATOM   797  H  HD13 . LEU A 1 63  ? -8.92   -9.08   57.072 1   32.426  ? 52  LEU A HD13 1 
ATOM   798  H  HD21 . LEU A 1 63  ? -11.582 -6.658  56.918 1   33.407  ? 52  LEU A HD21 1 
ATOM   799  H  HD22 . LEU A 1 63  ? -10.855 -7.625  57.944 1   33.41   ? 52  LEU A HD22 1 
ATOM   800  H  HD23 . LEU A 1 63  ? -11.867 -8.218  56.875 1   33.405  ? 52  LEU A HD23 1 
ATOM   801  N  N    . MET A 1 64  ? -8.549  -5.564  53.217 1   31.175  ? 53  MET A N    1 
ATOM   802  C  CA   . MET A 1 64  ? -8.89   -5.551  51.8   1   32.35   ? 53  MET A CA   1 
ATOM   803  C  C    . MET A 1 64  ? -7.706  -6.097  50.991 1   33.529  ? 53  MET A C    1 
ATOM   804  O  O    . MET A 1 64  ? -7.928  -6.755  49.997 1   39.811  ? 53  MET A O    1 
ATOM   805  C  CB   . MET A 1 64  ? -9.285  -4.148  51.288 1   28.314  ? 53  MET A CB   1 
ATOM   806  C  CG   . MET A 1 64  ? -10.58  -3.536  51.828 1   32.758  ? 53  MET A CG   1 
ATOM   807  S  SD   . MET A 1 64  ? -10.559 -1.725  51.692 1   38.392  ? 53  MET A SD   1 
ATOM   808  C  CE   . MET A 1 64  ? -10.284 -1.667  49.905 1   38.541  ? 53  MET A CE   1 
ATOM   809  H  H    . MET A 1 64  ? -8.514  -4.774  53.675 1   31.303  ? 53  MET A H    1 
ATOM   810  H  HA   . MET A 1 64  ? -9.658  -6.165  51.669 1   31.521  ? 53  MET A HA   1 
ATOM   811  H  HB2  . MET A 1 64  ? -8.547  -3.535  51.494 1   30.225  ? 53  MET A HB2  1 
ATOM   812  H  HB3  . MET A 1 64  ? -9.354  -4.196  50.31  1   30.272  ? 53  MET A HB3  1 
ATOM   813  H  HG2  . MET A 1 64  ? -11.343 -3.884  51.324 1   32.604  ? 53  MET A HG2  1 
ATOM   814  H  HG3  . MET A 1 64  ? -10.696 -3.785  52.766 1   32.59   ? 53  MET A HG3  1 
ATOM   815  H  HE1  . MET A 1 64  ? -10.541 -0.79   49.566 1   38.47   ? 53  MET A HE1  1 
ATOM   816  H  HE2  . MET A 1 64  ? -9.34   -1.824  49.716 1   38.436  ? 53  MET A HE2  1 
ATOM   817  H  HE3  . MET A 1 64  ? -10.823 -2.354  49.471 1   38.484  ? 53  MET A HE3  1 
ATOM   818  N  N    . ASP A 1 65  ? -6.458  -5.805  51.396 1   29.897  ? 54  ASP A N    1 
ATOM   819  C  CA   . ASP A 1 65  ? -5.314  -6.314  50.691 1   31.216  ? 54  ASP A CA   1 
ATOM   820  C  C    . ASP A 1 65  ? -5.147  -7.821  50.867 1   40.208  ? 54  ASP A C    1 
ATOM   821  O  O    . ASP A 1 65  ? -4.918  -8.543  49.893 1   31.874  ? 54  ASP A O    1 
ATOM   822  C  CB   . ASP A 1 65  ? -4.035  -5.652  51.119 1   34.059  ? 54  ASP A CB   1 
ATOM   823  C  CG   . ASP A 1 65  ? -3.872  -4.171  50.81  1   43.227  ? 54  ASP A CG   1 
ATOM   824  O  OD1  . ASP A 1 65  ? -4.807  -3.59   50.186 1   40.356  ? 54  ASP A OD1  1 
ATOM   825  O  OD2  . ASP A 1 65  ? -2.754  -3.612  51.163 1   44.836  ? 54  ASP A OD2  1 
ATOM   826  H  H    . ASP A 1 65  ? -6.329  -5.271  52.126 1   31.055  ? 54  ASP A H    1 
ATOM   827  H  HA   . ASP A 1 65  ? -5.435  -6.125  49.733 1   33.031  ? 54  ASP A HA   1 
ATOM   828  H  HB2  . ASP A 1 65  ? -3.944  -5.765  52.088 1   35.253  ? 54  ASP A HB2  1 
ATOM   829  H  HB3  . ASP A 1 65  ? -3.287  -6.124  50.696 1   35.29   ? 54  ASP A HB3  1 
ATOM   830  N  N    . VAL A 1 66  ? -5.197  -8.342  52.085 1   32.232  ? 55  VAL A N    1 
ATOM   831  C  CA   . VAL A 1 66  ? -4.929  -9.771  52.221 1   33.405  ? 55  VAL A CA   1 
ATOM   832  C  C    . VAL A 1 66  ? -6.104  -10.607 51.705 1   31.221  ? 55  VAL A C    1 
ATOM   833  O  O    . VAL A 1 66  ? -5.947  -11.774 51.436 1   30.711  ? 55  VAL A O    1 
ATOM   834  C  CB   . VAL A 1 66  ? -4.578  -10.152 53.68  1   35.029  ? 55  VAL A CB   1 
ATOM   835  C  CG1  . VAL A 1 66  ? -3.515  -9.232  54.234 1   34.561  ? 55  VAL A CG1  1 
ATOM   836  C  CG2  . VAL A 1 66  ? -5.803  -10.172 54.528 1   34.373  ? 55  VAL A CG2  1 
ATOM   837  H  H    . VAL A 1 66  ? -5.404  -7.836  52.817 1   34.24   ? 55  VAL A H    1 
ATOM   838  H  HA   . VAL A 1 66  ? -4.15   -9.98   51.669 1   33.076  ? 55  VAL A HA   1 
ATOM   839  H  HB   . VAL A 1 66  ? -4.207  -11.066 53.661 1   34.514  ? 55  VAL A HB   1 
ATOM   840  H  HG11 . VAL A 1 66  ? -3.917  -8.386  54.49  1   34.643  ? 55  VAL A HG11 1 
ATOM   841  H  HG12 . VAL A 1 66  ? -2.835  -9.075  53.556 1   34.679  ? 55  VAL A HG12 1 
ATOM   842  H  HG13 . VAL A 1 66  ? -3.105  -9.642  55.014 1   34.685  ? 55  VAL A HG13 1 
ATOM   843  H  HG21 . VAL A 1 66  ? -5.551  -10.099 55.464 1   34.555  ? 55  VAL A HG21 1 
ATOM   844  H  HG22 . VAL A 1 66  ? -6.283  -11.005 54.389 1   34.541  ? 55  VAL A HG22 1 
ATOM   845  H  HG23 . VAL A 1 66  ? -6.378  -9.425  54.29  1   34.527  ? 55  VAL A HG23 1 
ATOM   846  N  N    . SER A 1 67  ? -7.32   -10.054 51.604 1   32.597  ? 56  SER A N    1 
ATOM   847  C  CA   . SER A 1 67  ? -8.402  -10.839 51.096 1   32.399  ? 56  SER A CA   1 
ATOM   848  C  C    . SER A 1 67  ? -8.36   -10.921 49.572 1   36.693  ? 56  SER A C    1 
ATOM   849  O  O    . SER A 1 67  ? -9.234  -11.555 49.008 1   36.01   ? 56  SER A O    1 
ATOM   850  C  CB   . SER A 1 67  ? -9.715  -10.256 51.463 1   34.06   ? 56  SER A CB   1 
ATOM   851  O  OG   . SER A 1 67  ? -9.863  -8.931  50.97  1   28.694  ? 56  SER A OG   1 
ATOM   852  H  H    . SER A 1 67  ? -7.468  -9.19   51.862 1   32.269  ? 56  SER A H    1 
ATOM   853  H  HA   . SER A 1 67  ? -8.342  -11.755 51.47  1   33.459  ? 56  SER A HA   1 
ATOM   854  H  HB2  . SER A 1 67  ? -10.429 -10.817 51.104 1   32.371  ? 56  SER A HB2  1 
ATOM   855  H  HB3  . SER A 1 67  ? -9.8    -10.248 52.435 1   32.337  ? 56  SER A HB3  1 
ATOM   856  H  HG   . SER A 1 67  ? -10.62  -8.63   51.208 0   28.93   ? 56  SER A HG   1 
ATOM   857  N  N    . GLY A 1 68  ? -7.505  -10.162 48.923 1   36.411  ? 57  GLY A N    1 
ATOM   858  C  CA   . GLY A 1 68  ? -7.44   -10.191 47.457 1   41.806  ? 57  GLY A CA   1 
ATOM   859  C  C    . GLY A 1 68  ? -8.395  -9.203  46.768 1   41.321  ? 57  GLY A C    1 
ATOM   860  O  O    . GLY A 1 68  ? -8.528  -9.218  45.566 1   40.848  ? 57  GLY A O    1 
ATOM   861  H  H    . GLY A 1 68  ? -6.951  -9.597  49.379 1   37.511  ? 57  GLY A H    1 
ATOM   862  H  HA2  . GLY A 1 68  ? -6.516  -9.986  47.181 1   40.341  ? 57  GLY A HA2  1 
ATOM   863  H  HA3  . GLY A 1 68  ? -7.644  -11.105 47.147 1   40.305  ? 57  GLY A HA3  1 
ATOM   864  N  N    . LEU A 1 69  ? -9.04   -8.295  47.505 1   49.151  ? 58  LEU A N    1 
ATOM   865  C  CA   . LEU A 1 69  ? -10.042 -7.404  46.936 1   40.832  ? 58  LEU A CA   1 
ATOM   866  C  C    . LEU A 1 69  ? -9.384  -6.189  46.286 1   37.026  ? 58  LEU A C    1 
ATOM   867  O  O    . LEU A 1 69  ? -9.804  -5.721  45.235 1   36.112  ? 58  LEU A O    1 
ATOM   868  C  CB   . LEU A 1 69  ? -11.032 -6.918  47.996 1   37.334  ? 58  LEU A CB   1 
ATOM   869  C  CG   . LEU A 1 69  ? -12.111 -5.978  47.47  1   40.962  ? 58  LEU A CG   1 
ATOM   870  C  CD1  . LEU A 1 69  ? -12.928 -6.734  46.483 1   41.89   ? 58  LEU A CD1  1 
ATOM   871  C  CD2  . LEU A 1 69  ? -13.067 -5.442  48.452 1   41.82   ? 58  LEU A CD2  1 
ATOM   872  H  H    . LEU A 1 69  ? -8.847  -8.223  48.396 1   45.078  ? 58  LEU A H    1 
ATOM   873  H  HA   . LEU A 1 69  ? -10.535 -7.903  46.238 1   40.933  ? 58  LEU A HA   1 
ATOM   874  H  HB2  . LEU A 1 69  ? -11.468 -7.705  48.398 1   38.942  ? 58  LEU A HB2  1 
ATOM   875  H  HB3  . LEU A 1 69  ? -10.527 -6.452  48.701 1   38.921  ? 58  LEU A HB3  1 
ATOM   876  H  HG   . LEU A 1 69  ? -11.677 -5.217  47.007 1   40.563  ? 58  LEU A HG   1 
ATOM   877  H  HD11 . LEU A 1 69  ? -12.417 -6.86   45.665 1   41.589  ? 58  LEU A HD11 1 
ATOM   878  H  HD12 . LEU A 1 69  ? -13.738 -6.237  46.28  1   41.597  ? 58  LEU A HD12 1 
ATOM   879  H  HD13 . LEU A 1 69  ? -13.166 -7.601  46.851 1   41.56   ? 58  LEU A HD13 1 
ATOM   880  H  HD21 . LEU A 1 69  ? -12.581 -5.017  49.178 1   41.558  ? 58  LEU A HD21 1 
ATOM   881  H  HD22 . LEU A 1 69  ? -13.611 -6.165  48.807 1   41.56   ? 58  LEU A HD22 1 
ATOM   882  H  HD23 . LEU A 1 69  ? -13.643 -4.786  48.022 1   41.56   ? 58  LEU A HD23 1 
ATOM   883  N  N    . THR A 1 70  ? -8.412  -5.62   46.971 1   40.648  ? 59  THR A N    1 
ATOM   884  C  CA   . THR A 1 70  ? -7.728  -4.399  46.563 1   36.425  ? 59  THR A CA   1 
ATOM   885  C  C    . THR A 1 70  ? -7.298  -4.437  45.084 1   39.203  ? 59  THR A C    1 
ATOM   886  O  O    . THR A 1 70  ? -7.544  -3.494  44.338 1   33.564  ? 59  THR A O    1 
ATOM   887  C  CB   . THR A 1 70  ? -6.55   -4.197  47.507 1   34.576  ? 59  THR A CB   1 
ATOM   888  O  OG1  . THR A 1 70  ? -7.19   -3.813  48.725 1   38.994  ? 59  THR A OG1  1 
ATOM   889  C  CG2  . THR A 1 70  ? -5.618  -3.11   47.033 1   44.415  ? 59  THR A CG2  1 
ATOM   890  H  H    . THR A 1 70  ? -8.155  -6.011  47.757 1   38.816  ? 59  THR A H    1 
ATOM   891  H  HA   . THR A 1 70  ? -8.35   -3.649  46.684 1   37.363  ? 59  THR A HA   1 
ATOM   892  H  HB   . THR A 1 70  ? -6.054  -5.04   47.642 1   37.461  ? 59  THR A HB   1 
ATOM   893  H  HG1  . THR A 1 70  ? -7.646  -3.077  48.598 0   39.24   ? 59  THR A HG1  1 
ATOM   894  H  HG21 . THR A 1 70  ? -5.061  -2.814  47.772 1   41.204  ? 59  THR A HG21 1 
ATOM   895  H  HG22 . THR A 1 70  ? -6.137  -2.359  46.701 1   41.187  ? 59  THR A HG22 1 
ATOM   896  H  HG23 . THR A 1 70  ? -5.052  -3.453  46.321 1   41.201  ? 59  THR A HG23 1 
ATOM   897  N  N    . PRO A 1 71  ? -6.643  -5.462  44.553 1   38.577  ? 60  PRO A N    1 
ATOM   898  C  CA   . PRO A 1 71  ? -6.209  -5.407  43.14  1   46.561  ? 60  PRO A CA   1 
ATOM   899  C  C    . PRO A 1 71  ? -7.336  -5.341  42.13  1   43.738  ? 60  PRO A C    1 
ATOM   900  O  O    . PRO A 1 71  ? -7.074  -5.088  40.974 1   48.325  ? 60  PRO A O    1 
ATOM   901  C  CB   . PRO A 1 71  ? -5.403  -6.71   42.874 1   48.602  ? 60  PRO A CB   1 
ATOM   902  C  CG   . PRO A 1 71  ? -5.134  -7.269  44.29  1   46.022  ? 60  PRO A CG   1 
ATOM   903  C  CD   . PRO A 1 71  ? -6.218  -6.686  45.244 1   42.715  ? 60  PRO A CD   1 
ATOM   904  H  HA   . PRO A 1 71  ? -5.612  -4.626  43.022 1   44.661  ? 60  PRO A HA   1 
ATOM   905  H  HB2  . PRO A 1 71  ? -5.927  -7.349  42.336 1   47.539  ? 60  PRO A HB2  1 
ATOM   906  H  HB3  . PRO A 1 71  ? -4.558  -6.512  42.407 1   47.559  ? 60  PRO A HB3  1 
ATOM   907  H  HG2  . PRO A 1 71  ? -5.182  -8.248  44.283 1   45.822  ? 60  PRO A HG2  1 
ATOM   908  H  HG3  . PRO A 1 71  ? -4.24   -7.008  44.595 1   45.822  ? 60  PRO A HG3  1 
ATOM   909  H  HD2  . PRO A 1 71  ? -6.966  -7.31   45.349 1   42.33   ? 60  PRO A HD2  1 
ATOM   910  H  HD3  . PRO A 1 71  ? -5.839  -6.485  46.125 1   42.287  ? 60  PRO A HD3  1 
ATOM   911  N  N    . GLN A 1 72  ? -8.559  -5.653  42.565 1   40.438  ? 61  GLN A N    1 
ATOM   912  C  CA   . GLN A 1 72  ? -9.733  -5.596  41.73  1   35.188  ? 61  GLN A CA   1 
ATOM   913  C  C    . GLN A 1 72  ? -10.416 -4.225  41.793 1   44.155  ? 61  GLN A C    1 
ATOM   914  O  O    . GLN A 1 72  ? -11.434 -4.036  41.199 1   36.59   ? 61  GLN A O    1 
ATOM   915  C  CB   . GLN A 1 72  ? -10.633 -6.724  42.192 1   37.943  ? 61  GLN A CB   1 
ATOM   916  C  CG   . GLN A 1 72  ? -9.887  -8.06   42.191 1   42.768  ? 61  GLN A CG   1 
ATOM   917  C  CD   . GLN A 1 72  ? -10.803 -9.182  42.593 1   51.056  ? 61  GLN A CD   1 
ATOM   918  O  OE1  . GLN A 1 72  ? -10.767 -9.713  43.721 1   48.786  ? 61  GLN A OE1  1 
ATOM   919  N  NE2  . GLN A 1 72  ? -11.69  -9.487  41.663 1   48.903  ? 61  GLN A NE2  1 
ATOM   920  H  H    . GLN A 1 72  ? -8.663  -5.916  43.433 1   39.96   ? 61  GLN A H    1 
ATOM   921  H  HA   . GLN A 1 72  ? -9.462  -5.771  40.793 1   38.286  ? 61  GLN A HA   1 
ATOM   922  H  HB2  . GLN A 1 72  ? -10.959 -6.533  43.095 1   38.326  ? 61  GLN A HB2  1 
ATOM   923  H  HB3  . GLN A 1 72  ? -11.408 -6.784  41.595 1   38.424  ? 61  GLN A HB3  1 
ATOM   924  H  HG2  . GLN A 1 72  ? -9.528  -8.237  41.295 1   43.401  ? 61  GLN A HG2  1 
ATOM   925  H  HG3  . GLN A 1 72  ? -9.135  -8.022  42.818 1   43.344  ? 61  GLN A HG3  1 
ATOM   926  H  HE21 . GLN A 1 72  ? -12.283 -10.129 41.815 1   49.489  ? 61  GLN A HE21 1 
ATOM   927  H  HE22 . GLN A 1 72  ? -11.696 -9.054  40.889 1   49.278  ? 61  GLN A HE22 1 
ATOM   928  N  N    . LEU A 1 73  ? -9.817  -3.217  42.404 1   38.887  ? 62  LEU A N    1 
ATOM   929  C  CA   . LEU A 1 73  ? -10.518 -1.954  42.56  1   39.177  ? 62  LEU A CA   1 
ATOM   930  C  C    . LEU A 1 73  ? -9.73   -0.923  41.783 1   37.689  ? 62  LEU A C    1 
ATOM   931  O  O    . LEU A 1 73  ? -8.557  -1.152  41.555 1   35.133  ? 62  LEU A O    1 
ATOM   932  C  CB   . LEU A 1 73  ? -10.57  -1.559  44.045 1   41.209  ? 62  LEU A CB   1 
ATOM   933  C  CG   . LEU A 1 73  ? -11.405 -2.438  44.983 1   43.122  ? 62  LEU A CG   1 
ATOM   934  C  CD1  . LEU A 1 73  ? -11.308 -2.039  46.47  1   41.489  ? 62  LEU A CD1  1 
ATOM   935  C  CD2  . LEU A 1 73  ? -12.857 -2.423  44.52  1   41.15   ? 62  LEU A CD2  1 
ATOM   936  H  H    . LEU A 1 73  ? -8.967  -3.302  42.728 1   40.175  ? 62  LEU A H    1 
ATOM   937  H  HA   . LEU A 1 73  ? -11.434 -2.027  42.192 1   39.23   ? 62  LEU A HA   1 
ATOM   938  H  HB2  . LEU A 1 73  ? -9.646  -1.538  44.386 1   41.158  ? 62  LEU A HB2  1 
ATOM   939  H  HB3  . LEU A 1 73  ? -10.914 -0.638  44.102 1   41.145  ? 62  LEU A HB3  1 
ATOM   940  H  HG   . LEU A 1 73  ? -11.074 -3.369  44.901 1   42.057  ? 62  LEU A HG   1 
ATOM   941  H  HD11 . LEU A 1 73  ? -10.384 -2.1    46.763 1   41.958  ? 62  LEU A HD11 1 
ATOM   942  H  HD12 . LEU A 1 73  ? -11.857 -2.638  47.004 1   41.956  ? 62  LEU A HD12 1 
ATOM   943  H  HD13 . LEU A 1 73  ? -11.623 -1.126  46.583 1   41.958  ? 62  LEU A HD13 1 
ATOM   944  H  HD21 . LEU A 1 73  ? -12.948 -2.959  43.715 1   41.689  ? 62  LEU A HD21 1 
ATOM   945  H  HD22 . LEU A 1 73  ? -13.13  -1.509  44.332 1   41.707  ? 62  LEU A HD22 1 
ATOM   946  H  HD23 . LEU A 1 73  ? -13.425 -2.791  45.218 1   41.713  ? 62  LEU A HD23 1 
ATOM   947  N  N    . ALA A 1 74  ? -10.286 0.259   41.5   1   38.697  ? 63  ALA A N    1 
ATOM   948  C  CA   . ALA A 1 74  ? -9.408  1.295   40.967 1   46.662  ? 63  ALA A CA   1 
ATOM   949  C  C    . ALA A 1 74  ? -8.87   2.165   42.123 1   38.933  ? 63  ALA A C    1 
ATOM   950  O  O    . ALA A 1 74  ? -9.588  2.961   42.712 1   37.563  ? 63  ALA A O    1 
ATOM   951  C  CB   . ALA A 1 74  ? -10.132 2.088   39.888 1   43.144  ? 63  ALA A CB   1 
ATOM   952  H  H    . ALA A 1 74  ? -11.176 0.423   41.631 1   40.085  ? 63  ALA A H    1 
ATOM   953  H  HA   . ALA A 1 74  ? -8.627  0.845   40.542 1   42.78   ? 63  ALA A HA   1 
ATOM   954  H  HB1  . ALA A 1 74  ? -10.422 1.489   39.18  1   44.177  ? 63  ALA A HB1  1 
ATOM   955  H  HB2  . ALA A 1 74  ? -10.907 2.531   40.272 1   44.177  ? 63  ALA A HB2  1 
ATOM   956  H  HB3  . ALA A 1 74  ? -9.532  2.757   39.516 1   44.257  ? 63  ALA A HB3  1 
ATOM   957  N  N    . LEU A 1 75  ? -7.573  2.015   42.432 1   40.137  ? 64  LEU A N    1 
ATOM   958  C  CA   . LEU A 1 75  ? -6.921  2.726   43.528 1   40.028  ? 64  LEU A CA   1 
ATOM   959  C  C    . LEU A 1 75  ? -6.511  4.118   43.068 1   41.345  ? 64  LEU A C    1 
ATOM   960  O  O    . LEU A 1 75  ? -5.913  4.278   42.017 1   37.849  ? 64  LEU A O    1 
ATOM   961  C  CB   . LEU A 1 75  ? -5.668  1.966   43.948 1   42.384  ? 64  LEU A CB   1 
ATOM   962  C  CG   . LEU A 1 75  ? -5.881  0.507   44.359 1   48.079  ? 64  LEU A CG   1 
ATOM   963  C  CD1  . LEU A 1 75  ? -4.58   -0.036  44.911 1   53.765  ? 64  LEU A CD1  1 
ATOM   964  C  CD2  . LEU A 1 75  ? -7.057  0.381   45.318 1   39.837  ? 64  LEU A CD2  1 
ATOM   965  H  H    . LEU A 1 75  ? -7.069  1.441   41.93  1   39.991  ? 64  LEU A H    1 
ATOM   966  H  HA   . LEU A 1 75  ? -7.548  2.793   44.291 1   40.621  ? 64  LEU A HA   1 
ATOM   967  H  HB2  . LEU A 1 75  ? -5.029  1.987   43.199 1   43.06   ? 64  LEU A HB2  1 
ATOM   968  H  HB3  . LEU A 1 75  ? -5.257  2.445   44.705 1   43.153  ? 64  LEU A HB3  1 
ATOM   969  H  HG   . LEU A 1 75  ? -6.101  -0.011  43.543 1   46.245  ? 64  LEU A HG   1 
ATOM   970  H  HD11 . LEU A 1 75  ? -3.886  0.034   44.235 1   51.996  ? 64  LEU A HD11 1 
ATOM   971  H  HD12 . LEU A 1 75  ? -4.697  -0.968  45.16  1   51.996  ? 64  LEU A HD12 1 
ATOM   972  H  HD13 . LEU A 1 75  ? -4.32   0.477   45.695 1   51.946  ? 64  LEU A HD13 1 
ATOM   973  H  HD21 . LEU A 1 75  ? -7.89   0.454   44.822 1   42.099  ? 64  LEU A HD21 1 
ATOM   974  H  HD22 . LEU A 1 75  ? -7.012  1.089   45.982 1   42.109  ? 64  LEU A HD22 1 
ATOM   975  H  HD23 . LEU A 1 75  ? -7.022  -0.482  45.763 1   42.103  ? 64  LEU A HD23 1 
ATOM   976  N  N    . ARG A 1 76  ? -6.785  5.097   43.908 1   39.217  ? 65  ARG A N    1 
ATOM   977  C  CA   . ARG A 1 76  ? -6.45   6.47    43.614 1   39.267  ? 65  ARG A CA   1 
ATOM   978  C  C    . ARG A 1 76  ? -6.196  7.257   44.906 1   36.116  ? 65  ARG A C    1 
ATOM   979  O  O    . ARG A 1 76  ? -6.736  7.024   45.992 1   34.896  ? 65  ARG A O    1 
ATOM   980  C  CB   . ARG A 1 76  ? -7.599  7.187   42.889 1   48.943  ? 65  ARG A CB   1 
ATOM   981  C  CG   . ARG A 1 76  ? -8.252  6.578   41.648 1   52.821  ? 65  ARG A CG   1 
ATOM   982  C  CD   . ARG A 1 76  ? -7.66   6.926   40.295 1   53.659  ? 65  ARG A CD   1 
ATOM   983  N  NE   . ARG A 1 76  ? -8.394  6.231   39.213 1   65.234  ? 65  ARG A NE   1 
ATOM   984  C  CZ   . ARG A 1 76  ? -8.031  5.027   38.648 1   71.356  ? 65  ARG A CZ   1 
ATOM   985  N  NH1  . ARG A 1 76  ? -7.143  4.223   39.21  1   54.358  ? 65  ARG A NH1  1 
ATOM   986  N  NH2  . ARG A 1 76  ? -8.579  4.555   37.531 1   72.755  ? 65  ARG A NH2  1 
ATOM   987  H  H    . ARG A 1 76  ? -7.2    4.907   44.7   1   39.71   ? 65  ARG A H    1 
ATOM   988  H  HA   . ARG A 1 76  ? -5.633  6.488   43.053 1   40.178  ? 65  ARG A HA   1 
ATOM   989  H  HB2  . ARG A 1 76  ? -8.308  7.329   43.551 1   47.225  ? 65  ARG A HB2  1 
ATOM   990  H  HB3  . ARG A 1 76  ? -7.267  8.076   42.639 1   47.255  ? 65  ARG A HB3  1 
ATOM   991  H  HG2  . ARG A 1 76  ? -8.247  5.602   41.741 1   51.877  ? 65  ARG A HG2  1 
ATOM   992  H  HG3  . ARG A 1 76  ? -9.198  6.844   41.642 1   52.056  ? 65  ARG A HG3  1 
ATOM   993  H  HD2  . ARG A 1 76  ? -7.711  7.893   40.153 1   55.971  ? 65  ARG A HD2  1 
ATOM   994  H  HD3  . ARG A 1 76  ? -6.717  6.662   40.271 1   55.964  ? 65  ARG A HD3  1 
ATOM   995  H  HE   . ARG A 1 76  ? -9.115  6.611   38.906 1   63.776  ? 65  ARG A HE   1 
ATOM   996  H  HH11 . ARG A 1 76  ? -7.198  4.045   40.074 1   59.162  ? 65  ARG A HH11 1 
ATOM   997  H  HH12 . ARG A 1 76  ? -6.499  3.868   38.719 1   59.303  ? 65  ARG A HH12 1 
ATOM   998  H  HH21 . ARG A 1 76  ? -9.167  5.047   37.091 1   72.184  ? 65  ARG A HH21 1 
ATOM   999  H  HH22 . ARG A 1 76  ? -8.357  3.752   37.233 1   72.023  ? 65  ARG A HH22 1 
ATOM   1000 N  N    . SER A 1 77  ? -5.372  8.25    44.724 1   36.89   ? 66  SER A N    1 
ATOM   1001 C  CA   . SER A 1 77  ? -5.17   9.326   45.647 1   37.053  ? 66  SER A CA   1 
ATOM   1002 C  C    . SER A 1 77  ? -5.811  10.543  45.01  1   38.164  ? 66  SER A C    1 
ATOM   1003 O  O    . SER A 1 77  ? -6.629  10.388  44.142 1   41.441  ? 66  SER A O    1 
ATOM   1004 C  CB   . SER A 1 77  ? -3.688  9.547   45.863 1   38.984  ? 66  SER A CB   1 
ATOM   1005 O  OG   . SER A 1 77  ? -3.502  10.42   46.98  1   47.817  ? 66  SER A OG   1 
ATOM   1006 H  H    . SER A 1 77  ? -4.884  8.261   43.951 1   36.805  ? 66  SER A H    1 
ATOM   1007 H  HA   . SER A 1 77  ? -5.614  9.124   46.509 1   37.542  ? 66  SER A HA   1 
ATOM   1008 H  HB2  . SER A 1 77  ? -3.251  8.692   46.036 1   40.468  ? 66  SER A HB2  1 
ATOM   1009 H  HB3  . SER A 1 77  ? -3.294  9.945   45.063 1   40.458  ? 66  SER A HB3  1 
ATOM   1010 H  HG   . SER A 1 77  ? -2.68   10.516  47.099 0   47.65   ? 66  SER A HG   1 
ATOM   1011 N  N    . ALA A 1 78  ? -5.414  11.733  45.461 1   39.084  ? 67  ALA A N    1 
ATOM   1012 C  CA   . ALA A 1 78  ? -5.96   12.968  44.966 1   40.418  ? 67  ALA A CA   1 
ATOM   1013 C  C    . ALA A 1 78  ? -5.037  14.097  45.354 1   42.613  ? 67  ALA A C    1 
ATOM   1014 O  O    . ALA A 1 78  ? -4.297  13.997  46.341 1   39.85   ? 67  ALA A O    1 
ATOM   1015 C  CB   . ALA A 1 78  ? -7.301  13.221  45.593 1   47.7    ? 67  ALA A CB   1 
ATOM   1016 H  H    . ALA A 1 78  ? -4.78   11.771  46.118 1   39.17   ? 67  ALA A H    1 
ATOM   1017 H  HA   . ALA A 1 78  ? -6.038  12.926  43.973 1   41.77   ? 67  ALA A HA   1 
ATOM   1018 H  HB1  . ALA A 1 78  ? -7.919  12.513  45.342 1   45.35   ? 67  ALA A HB1  1 
ATOM   1019 H  HB2  . ALA A 1 78  ? -7.212  13.239  46.561 1   45.366  ? 67  ALA A HB2  1 
ATOM   1020 H  HB3  . ALA A 1 78  ? -7.65   14.075  45.287 1   45.353  ? 67  ALA A HB3  1 
ATOM   1021 N  N    . ALA A 1 79  ? -5.239  15.216  44.66  1   42.245  ? 68  ALA A N    1 
ATOM   1022 C  CA   . ALA A 1 79  ? -4.706  16.506  45.081 1   42.061  ? 68  ALA A CA   1 
ATOM   1023 C  C    . ALA A 1 79  ? -5.538  17.001  46.259 1   42.355  ? 68  ALA A C    1 
ATOM   1024 O  O    . ALA A 1 79  ? -6.767  16.781  46.329 1   39.739  ? 68  ALA A O    1 
ATOM   1025 C  CB   . ALA A 1 79  ? -4.791  17.493  43.934 1   45.112  ? 68  ALA A CB   1 
ATOM   1026 H  H    . ALA A 1 79  ? -5.731  15.178  43.891 1   42.292  ? 68  ALA A H    1 
ATOM   1027 H  HA   . ALA A 1 79  ? -3.759  16.39   45.366 1   42.617  ? 68  ALA A HA   1 
ATOM   1028 H  HB1  . ALA A 1 79  ? -4.282  17.159  43.176 1   44.187  ? 68  ALA A HB1  1 
ATOM   1029 H  HB2  . ALA A 1 79  ? -5.719  17.61   43.671 1   44.187  ? 68  ALA A HB2  1 
ATOM   1030 H  HB3  . ALA A 1 79  ? -4.426  18.351  44.212 1   44.187  ? 68  ALA A HB3  1 
ATOM   1031 N  N    . PRO A 1 80  ? -4.913  17.733  47.19  1   37.831  ? 69  PRO A N    1 
ATOM   1032 C  CA   . PRO A 1 80  ? -5.64   18.23   48.35  1   37.199  ? 69  PRO A CA   1 
ATOM   1033 C  C    . PRO A 1 80  ? -6.682  19.227  47.899 1   39.595  ? 69  PRO A C    1 
ATOM   1034 O  O    . PRO A 1 80  ? -6.565  19.785  46.857 1   34.716  ? 69  PRO A O    1 
ATOM   1035 C  CB   . PRO A 1 80  ? -4.642  18.86   49.272 1   35.148  ? 69  PRO A CB   1 
ATOM   1036 C  CG   . PRO A 1 80  ? -3.376  18.913  48.462 1   41.156  ? 69  PRO A CG   1 
ATOM   1037 C  CD   . PRO A 1 80  ? -3.467  17.975  47.256 1   41.844  ? 69  PRO A CD   1 
ATOM   1038 H  HA   . PRO A 1 80  ? -6.078  17.47   48.806 1   37.397  ? 69  PRO A HA   1 
ATOM   1039 H  HB2  . PRO A 1 80  ? -4.928  19.766  49.538 1   36.915  ? 69  PRO A HB2  1 
ATOM   1040 H  HB3  . PRO A 1 80  ? -4.518  18.313  50.083 1   36.903  ? 69  PRO A HB3  1 
ATOM   1041 H  HG2  . PRO A 1 80  ? -3.219  19.829  48.153 1   39.835  ? 69  PRO A HG2  1 
ATOM   1042 H  HG3  . PRO A 1 80  ? -2.615  18.653  49.022 1   39.835  ? 69  PRO A HG3  1 
ATOM   1043 H  HD2  . PRO A 1 80  ? -3.137  18.411  46.439 1   40.745  ? 69  PRO A HD2  1 
ATOM   1044 H  HD3  . PRO A 1 80  ? -2.969  17.142  47.412 1   40.74   ? 69  PRO A HD3  1 
ATOM   1045 N  N    . ALA A 1 81  ? -7.681  19.457  48.713 1   40.189  ? 70  ALA A N    1 
ATOM   1046 C  CA   . ALA A 1 81  ? -8.6    20.526  48.431 1   45.56   ? 70  ALA A CA   1 
ATOM   1047 C  C    . ALA A 1 81  ? -7.87   21.858  48.567 1   42.895  ? 70  ALA A C    1 
ATOM   1048 O  O    . ALA A 1 81  ? -7.053  22.03   49.466 1   41.903  ? 70  ALA A O    1 
ATOM   1049 C  CB   . ALA A 1 81  ? -9.795  20.449  49.357 1   46.243  ? 70  ALA A CB   1 
ATOM   1050 H  H    . ALA A 1 81  ? -7.8    18.944  49.46  1   41.135  ? 70  ALA A H    1 
ATOM   1051 H  HA   . ALA A 1 81  ? -8.913  20.43   47.489 1   43.986  ? 70  ALA A HA   1 
ATOM   1052 H  HB1  . ALA A 1 81  ? -10.249 19.598  49.235 1   46.039  ? 70  ALA A HB1  1 
ATOM   1053 H  HB2  . ALA A 1 81  ? -9.499  20.525  50.28  1   46.039  ? 70  ALA A HB2  1 
ATOM   1054 H  HB3  . ALA A 1 81  ? -10.411 21.173  49.158 1   46.039  ? 70  ALA A HB3  1 
ATOM   1055 N  N    . SER A 1 82  ? -8.107  22.738  47.584 1   41.402  ? 71  SER A N    1 
ATOM   1056 C  CA   . SER A 1 82  ? -7.512  24.069  47.51  1   49.792  ? 71  SER A CA   1 
ATOM   1057 C  C    . SER A 1 82  ? -8.174  24.993  48.526 1   37.784  ? 71  SER A C    1 
ATOM   1058 O  O    . SER A 1 82  ? -9.304  24.76   48.968 1   38.358  ? 71  SER A O    1 
ATOM   1059 C  CB   . SER A 1 82  ? -7.633  24.687  46.093 1   43.034  ? 71  SER A CB   1 
ATOM   1060 O  OG   . SER A 1 82  ? -9.014  24.956  45.824 1   45.307  ? 71  SER A OG   1 
ATOM   1061 H  H    . SER A 1 82  ? -8.681  22.492  46.916 1   43.551  ? 71  SER A H    1 
ATOM   1062 H  HA   . SER A 1 82  ? -6.551  23.992  47.738 1   44.44   ? 71  SER A HA   1 
ATOM   1063 H  HB2  . SER A 1 82  ? -7.119  25.516  46.05  1   44.988  ? 71  SER A HB2  1 
ATOM   1064 H  HB3  . SER A 1 82  ? -7.281  24.063  45.43  1   44.988  ? 71  SER A HB3  1 
ATOM   1065 H  HG   . SER A 1 82  ? -9.056  25.298  45.052 0   45.33   ? 71  SER A HG   1 
ATOM   1066 N  N    . LEU A 1 83  ? -7.503  26.106  48.792 1   44.519  ? 72  LEU A N    1 
ATOM   1067 C  CA   . LEU A 1 83  ? -8.065  27.143  49.647 1   45.58   ? 72  LEU A CA   1 
ATOM   1068 C  C    . LEU A 1 83  ? -9.421  27.635  49.115 1   41.314  ? 72  LEU A C    1 
ATOM   1069 O  O    . LEU A 1 83  ? -10.403 27.829  49.863 1   37.626  ? 72  LEU A O    1 
ATOM   1070 C  CB   . LEU A 1 83  ? -6.985  28.215  49.767 1   44.291  ? 72  LEU A CB   1 
ATOM   1071 C  CG   . LEU A 1 83  ? -7.36   29.457  50.58  1   61.269  ? 72  LEU A CG   1 
ATOM   1072 C  CD1  . LEU A 1 83  ? -7.88   29.095  51.978 1   46.299  ? 72  LEU A CD1  1 
ATOM   1073 C  CD2  . LEU A 1 83  ? -6.14   30.418  50.64  1   65.384  ? 72  LEU A CD2  1 
ATOM   1074 H  H    . LEU A 1 83  ? -6.67   26.227  48.434 1   43.167  ? 72  LEU A H    1 
ATOM   1075 H  HA   . LEU A 1 83  ? -8.217  26.745  50.541 1   44.34   ? 72  LEU A HA   1 
ATOM   1076 H  HB2  . LEU A 1 83  ? -6.189  27.804  50.177 1   47.976  ? 72  LEU A HB2  1 
ATOM   1077 H  HB3  . LEU A 1 83  ? -6.736  28.503  48.859 1   47.976  ? 72  LEU A HB3  1 
ATOM   1078 H  HG   . LEU A 1 83  ? -8.089  29.928  50.1   1   55.324  ? 72  LEU A HG   1 
ATOM   1079 H  HD11 . LEU A 1 83  ? -8.76   28.688  51.903 1   50.243  ? 72  LEU A HD11 1 
ATOM   1080 H  HD12 . LEU A 1 83  ? -7.942  29.899  52.52  1   50.263  ? 72  LEU A HD12 1 
ATOM   1081 H  HD13 . LEU A 1 83  ? -7.269  28.467  52.4   1   50.263  ? 72  LEU A HD13 1 
ATOM   1082 H  HD21 . LEU A 1 83  ? -5.893  30.688  49.739 1   64.167  ? 72  LEU A HD21 1 
ATOM   1083 H  HD22 . LEU A 1 83  ? -5.388  29.964  51.058 1   64.167  ? 72  LEU A HD22 1 
ATOM   1084 H  HD23 . LEU A 1 83  ? -6.371  31.205  51.161 1   64.167  ? 72  LEU A HD23 1 
ATOM   1085 N  N    . GLU A 1 84  ? -9.546  27.685  47.8   1   39.077  ? 73  GLU A N    1 
ATOM   1086 C  CA   . GLU A 1 84  ? -10.795 28.115  47.194 1   41.454  ? 73  GLU A CA   1 
ATOM   1087 C  C    . GLU A 1 84  ? -11.904 27.094  47.461 1   44.849  ? 73  GLU A C    1 
ATOM   1088 O  O    . GLU A 1 84  ? -13.064 27.444  47.645 1   40.88   ? 73  GLU A O    1 
ATOM   1089 C  CB   . GLU A 1 84  ? -10.477 28.252  45.7   1   45.544  ? 73  GLU A CB   1 
ATOM   1090 C  CG   . GLU A 1 84  ? -11.73  28.59   44.881 1   59.842  ? 73  GLU A CG   1 
ATOM   1091 C  CD   . GLU A 1 84  ? -11.638 28.717  43.338 1   66.823  ? 73  GLU A CD   1 
ATOM   1092 O  OE1  . GLU A 1 84  ? -10.723 28.266  42.593 1   59.194  ? 73  GLU A OE1  1 
ATOM   1093 O  OE2  . GLU A 1 84  ? -12.589 29.354  42.863 1   65.434  ? 73  GLU A OE2  1 
ATOM   1094 H  H    . GLU A 1 84  ? -8.841  27.463  47.262 1   40.272  ? 73  GLU A H    1 
ATOM   1095 H  HA   . GLU A 1 84  ? -11.053 28.994  47.574 1   42.246  ? 73  GLU A HA   1 
ATOM   1096 H  HB2  . GLU A 1 84  ? -9.804  28.955  45.58  1   47.414  ? 73  GLU A HB2  1 
ATOM   1097 H  HB3  . GLU A 1 84  ? -10.095 27.41   45.375 1   47.368  ? 73  GLU A HB3  1 
ATOM   1098 H  HG2  . GLU A 1 84  ? -12.409 27.91   45.073 1   57.462  ? 73  GLU A HG2  1 
ATOM   1099 H  HG3  . GLU A 1 84  ? -12.092 29.436  45.223 1   57.638  ? 73  GLU A HG3  1 
ATOM   1100 N  N    . ASP A 1 85  ? -11.554 25.792  47.412 1   43.595  ? 74  ASP A N    1 
ATOM   1101 C  CA   . ASP A 1 85  ? -12.509 24.762  47.733 1   36.176  ? 74  ASP A CA   1 
ATOM   1102 C  C    . ASP A 1 85  ? -13.001 24.902  49.152 1   33.264  ? 74  ASP A C    1 
ATOM   1103 O  O    . ASP A 1 85  ? -14.203 24.74   49.455 1   31.728  ? 74  ASP A O    1 
ATOM   1104 C  CB   . ASP A 1 85  ? -11.922 23.366  47.549 1   50.304  ? 74  ASP A CB   1 
ATOM   1105 C  CG   . ASP A 1 85  ? -11.581 22.973  46.122 1   48.135  ? 74  ASP A CG   1 
ATOM   1106 O  OD1  . ASP A 1 85  ? -12.33  23.451  45.243 1   46.843  ? 74  ASP A OD1  1 
ATOM   1107 O  OD2  . ASP A 1 85  ? -10.561 22.212  45.889 1   59.417  ? 74  ASP A OD2  1 
ATOM   1108 H  H    . ASP A 1 85  ? -10.706 25.554  47.166 1   42.099  ? 74  ASP A H    1 
ATOM   1109 H  HA   . ASP A 1 85  ? -13.276 24.856  47.128 1   39.441  ? 74  ASP A HA   1 
ATOM   1110 H  HB2  . ASP A 1 85  ? -11.109 23.289  48.088 1   46.117  ? 74  ASP A HB2  1 
ATOM   1111 H  HB3  . ASP A 1 85  ? -12.567 22.711  47.89  1   46.081  ? 74  ASP A HB3  1 
ATOM   1112 N  N    . LEU A 1 86  ? -12.059 25.18   50.035 1   31.122  ? 75  LEU A N    1 
ATOM   1113 C  CA   . LEU A 1 86  ? -12.424 25.243  51.438 1   37.301  ? 75  LEU A CA   1 
ATOM   1114 C  C    . LEU A 1 86  ? -13.286 26.468  51.68  1   39.813  ? 75  LEU A C    1 
ATOM   1115 O  O    . LEU A 1 86  ? -14.142 26.448  52.567 1   38.19   ? 75  LEU A O    1 
ATOM   1116 C  CB   . LEU A 1 86  ? -11.183 25.318  52.32  1   37.048  ? 75  LEU A CB   1 
ATOM   1117 C  CG   . LEU A 1 86  ? -10.102 24.24   52.185 1   46.628  ? 75  LEU A CG   1 
ATOM   1118 C  CD1  . LEU A 1 86  ? -8.951  24.458  53.187 1   54.653  ? 75  LEU A CD1  1 
ATOM   1119 C  CD2  . LEU A 1 86  ? -10.636 22.91   52.346 1   33.759  ? 75  LEU A CD2  1 
ATOM   1120 H  H    . LEU A 1 86  ? -11.194 25.33   49.78  1   33.174  ? 75  LEU A H    1 
ATOM   1121 H  HA   . LEU A 1 86  ? -12.943 24.431  51.669 1   36.335  ? 75  LEU A HA   1 
ATOM   1122 H  HB2  . LEU A 1 86  ? -10.758 26.193  52.164 1   39.11   ? 75  LEU A HB2  1 
ATOM   1123 H  HB3  . LEU A 1 86  ? -11.484 25.328  53.258 1   39.106  ? 75  LEU A HB3  1 
ATOM   1124 H  HG   . LEU A 1 86  ? -9.721  24.302  51.274 1   43.096  ? 75  LEU A HG   1 
ATOM   1125 H  HD11 . LEU A 1 86  ? -8.676  25.39   53.168 1   52.129  ? 75  LEU A HD11 1 
ATOM   1126 H  HD12 . LEU A 1 86  ? -8.199  23.895  52.944 1   52.057  ? 75  LEU A HD12 1 
ATOM   1127 H  HD13 . LEU A 1 86  ? -9.251  24.228  54.083 1   52.041  ? 75  LEU A HD13 1 
ATOM   1128 H  HD21 . LEU A 1 86  ? -11.243 22.712  51.613 1   37.323  ? 75  LEU A HD21 1 
ATOM   1129 H  HD22 . LEU A 1 86  ? -11.117 22.852  53.188 1   37.323  ? 75  LEU A HD22 1 
ATOM   1130 H  HD23 . LEU A 1 86  ? -9.909  22.265  52.345 1   37.391  ? 75  LEU A HD23 1 
ATOM   1131 N  N    . ARG A 1 87  ? -13.01  27.564  50.94  1   39.868  ? 76  ARG A N    1 
ATOM   1132 C  CA   . ARG A 1 87  ? -13.749 28.804  51.208 1   41.188  ? 76  ARG A CA   1 
ATOM   1133 C  C    . ARG A 1 87  ? -15.189 28.782  50.684 1   42.365  ? 76  ARG A C    1 
ATOM   1134 O  O    . ARG A 1 87  ? -15.947 29.657  51.014 1   46.702  ? 76  ARG A O    1 
ATOM   1135 C  CB   . ARG A 1 87  ? -13.067 30.008  50.589 1   38.542  ? 76  ARG A CB   1 
ATOM   1136 C  CG   . ARG A 1 87  ? -11.875 30.506  51.387 1   45.424  ? 76  ARG A CG   1 
ATOM   1137 C  CD   . ARG A 1 87  ? -11.024 31.337  50.429 1   45.594  ? 76  ARG A CD   1 
ATOM   1138 N  NE   . ARG A 1 87  ? -10.079 32.156  51.19  1   49.88   ? 76  ARG A NE   1 
ATOM   1139 C  CZ   . ARG A 1 87  ? -9.024  32.813  50.707 1   55.249  ? 76  ARG A CZ   1 
ATOM   1140 N  NH1  . ARG A 1 87  ? -8.854  32.859  49.409 1   54.569  ? 76  ARG A NH1  1 
ATOM   1141 N  NH2  . ARG A 1 87  ? -8.16   33.418  51.516 1   52.393  ? 76  ARG A NH2  1 
ATOM   1142 H  H    . ARG A 1 87  ? -12.37  27.547  50.288 1   40.028  ? 76  ARG A H    1 
ATOM   1143 H  HA   . ARG A 1 87  ? -13.776 28.94   52.187 1   40.611  ? 76  ARG A HA   1 
ATOM   1144 H  HB2  . ARG A 1 87  ? -12.767 29.771  49.685 1   40.661  ? 76  ARG A HB2  1 
ATOM   1145 H  HB3  . ARG A 1 87  ? -13.716 30.738  50.506 1   40.677  ? 76  ARG A HB3  1 
ATOM   1146 H  HG2  . ARG A 1 87  ? -12.179 31.064  52.136 1   43.84   ? 76  ARG A HG2  1 
ATOM   1147 H  HG3  . ARG A 1 87  ? -11.352 29.747  51.726 1   43.807  ? 76  ARG A HG3  1 
ATOM   1148 H  HD2  . ARG A 1 87  ? -10.531 30.745  49.825 1   46.563  ? 76  ARG A HD2  1 
ATOM   1149 H  HD3  . ARG A 1 87  ? -11.599 31.919  49.89  1   46.492  ? 76  ARG A HD3  1 
ATOM   1150 H  HE   . ARG A 1 87  ? -10.213 32.222  52.046 1   50.049  ? 76  ARG A HE   1 
ATOM   1151 H  HH11 . ARG A 1 87  ? -9.473  33.23   48.898 1   54.722  ? 76  ARG A HH11 1 
ATOM   1152 H  HH12 . ARG A 1 87  ? -8.122  32.52   49.05  1   54.765  ? 76  ARG A HH12 1 
ATOM   1153 H  HH21 . ARG A 1 87  ? -8.151  33.222  52.379 1   53.227  ? 76  ARG A HH21 1 
ATOM   1154 H  HH22 . ARG A 1 87  ? -7.595  34.014  51.188 1   53.258  ? 76  ARG A HH22 1 
ATOM   1155 N  N    . ARG A 1 88  ? -15.598 27.791  49.892 1   41.09   ? 77  ARG A N    1 
ATOM   1156 C  CA   . ARG A 1 88  ? -17.014 27.64   49.633 1   37.026  ? 77  ARG A CA   1 
ATOM   1157 C  C    . ARG A 1 88  ? -17.76  27.213  50.898 1   42.827  ? 77  ARG A C    1 
ATOM   1158 O  O    . ARG A 1 88  ? -18.967 27.237  50.933 1   46.889  ? 77  ARG A O    1 
ATOM   1159 C  CB   . ARG A 1 88  ? -17.413 26.609  48.578 1   39.717  ? 77  ARG A CB   1 
ATOM   1160 C  CG   . ARG A 1 88  ? -16.768 26.873  47.234 1   43.879  ? 77  ARG A CG   1 
ATOM   1161 C  CD   . ARG A 1 88  ? -17.316 25.994  46.113 1   37.613  ? 77  ARG A CD   1 
ATOM   1162 N  NE   . ARG A 1 88  ? -16.479 26.342  44.963 1   42.118  ? 77  ARG A NE   1 
ATOM   1163 C  CZ   . ARG A 1 88  ? -15.39  25.68   44.626 1   55.972  ? 77  ARG A CZ   1 
ATOM   1164 N  NH1  . ARG A 1 88  ? -15.065 24.55   45.253 1   51.079  ? 77  ARG A NH1  1 
ATOM   1165 N  NH2  . ARG A 1 88  ? -14.667 26.091  43.601 1   46.151  ? 77  ARG A NH2  1 
ATOM   1166 H  H    . ARG A 1 88  ? -15.001 27.217  49.505 1   40.45   ? 77  ARG A H    1 
ATOM   1167 H  HA   . ARG A 1 88  ? -17.369 28.519  49.344 1   39.362  ? 77  ARG A HA   1 
ATOM   1168 H  HB2  . ARG A 1 88  ? -17.152 25.715  48.887 1   40.021  ? 77  ARG A HB2  1 
ATOM   1169 H  HB3  . ARG A 1 88  ? -18.388 26.618  48.47  1   40.05   ? 77  ARG A HB3  1 
ATOM   1170 H  HG2  . ARG A 1 88  ? -16.905 27.815  46.994 1   41.423  ? 77  ARG A HG2  1 
ATOM   1171 H  HG3  . ARG A 1 88  ? -15.8   26.725  47.31  1   41.466  ? 77  ARG A HG3  1 
ATOM   1172 H  HD2  . ARG A 1 88  ? -17.24  25.043  46.32  1   40.184  ? 77  ARG A HD2  1 
ATOM   1173 H  HD3  . ARG A 1 88  ? -18.251 26.211  45.923 1   40.013  ? 77  ARG A HD3  1 
ATOM   1174 H  HE   . ARG A 1 88  ? -16.715 27.024  44.475 1   43.963  ? 77  ARG A HE   1 
ATOM   1175 H  HH11 . ARG A 1 88  ? -15.245 24.438  46.11  1   52.092  ? 77  ARG A HH11 1 
ATOM   1176 H  HH12 . ARG A 1 88  ? -14.647 23.916  44.802 1   52.218  ? 77  ARG A HH12 1 
ATOM   1177 H  HH21 . ARG A 1 88  ? -14.954 26.757  43.094 1   48.886  ? 77  ARG A HH21 1 
ATOM   1178 H  HH22 . ARG A 1 88  ? -13.895 25.698  43.423 1   48.996  ? 77  ARG A HH22 1 
ATOM   1179 N  N    . ILE A 1 89  ? -17.095 26.777  51.949 1   35.057  ? 78  ILE A N    1 
ATOM   1180 C  CA   . ILE A 1 89  ? -17.861 26.347  53.098 1   34.36   ? 78  ILE A CA   1 
ATOM   1181 C  C    . ILE A 1 89  ? -17.45  27.125  54.335 1   30.123  ? 78  ILE A C    1 
ATOM   1182 O  O    . ILE A 1 89  ? -18.278 27.438  55.158 1   34.734  ? 78  ILE A O    1 
ATOM   1183 C  CB   . ILE A 1 89  ? -17.602 24.843  53.341 1   40.647  ? 78  ILE A CB   1 
ATOM   1184 C  CG1  . ILE A 1 89  ? -18.165 24      52.266 1   35.425  ? 78  ILE A CG1  1 
ATOM   1185 C  CG2  . ILE A 1 89  ? -18.152 24.479  54.719 1   38.581  ? 78  ILE A CG2  1 
ATOM   1186 C  CD1  . ILE A 1 89  ? -19.695 24.036  52.249 1   41.17   ? 78  ILE A CD1  1 
ATOM   1187 H  H    . ILE A 1 89  ? -16.185 26.701  51.946 1   36.653  ? 78  ILE A H    1 
ATOM   1188 H  HA   . ILE A 1 89  ? -18.81  26.488  52.933 1   34.888  ? 78  ILE A HA   1 
ATOM   1189 H  HB   . ILE A 1 89  ? -16.634 24.704  53.355 1   38.013  ? 78  ILE A HB   1 
ATOM   1190 H  HG12 . ILE A 1 89  ? -17.825 24.31   51.402 1   37.848  ? 78  ILE A HG12 1 
ATOM   1191 H  HG13 . ILE A 1 89  ? -17.868 23.076  52.396 1   37.848  ? 78  ILE A HG13 1 
ATOM   1192 H  HG21 . ILE A 1 89  ? -18.294 23.519  54.768 1   39.116  ? 78  ILE A HG21 1 
ATOM   1193 H  HG22 . ILE A 1 89  ? -18.998 24.935  54.867 1   39.058  ? 78  ILE A HG22 1 
ATOM   1194 H  HG23 . ILE A 1 89  ? -17.518 24.743  55.407 1   39.088  ? 78  ILE A HG23 1 
ATOM   1195 H  HD11 . ILE A 1 89  ? -20.046 23.74   53.109 1   39.362  ? 78  ILE A HD11 1 
ATOM   1196 H  HD12 . ILE A 1 89  ? -20.016 23.436  51.549 1   39.379  ? 78  ILE A HD12 1 
ATOM   1197 H  HD13 . ILE A 1 89  ? -20.009 24.941  52.064 1   39.331  ? 78  ILE A HD13 1 
ATOM   1198 N  N    . HIS A 1 90  ? -16.135 27.326  54.497 1   34.962  ? 79  HIS A N    1 
ATOM   1199 C  CA   . HIS A 1 90  ? -15.58  27.821  55.724 1   35.412  ? 79  HIS A CA   1 
ATOM   1200 C  C    . HIS A 1 90  ? -15.095 29.257  55.519 1   33.883  ? 79  HIS A C    1 
ATOM   1201 O  O    . HIS A 1 90  ? -14.343 29.533  54.591 1   35.488  ? 79  HIS A O    1 
ATOM   1202 C  CB   . HIS A 1 90  ? -14.318 27.001  56.065 1   38.614  ? 79  HIS A CB   1 
ATOM   1203 C  CG   . HIS A 1 90  ? -14.609 25.551  56.337 1   33.774  ? 79  HIS A CG   1 
ATOM   1204 N  ND1  . HIS A 1 90  ? -15.183 25.14   57.52  1   31.684  ? 79  HIS A ND1  1 
ATOM   1205 C  CD2  . HIS A 1 90  ? -14.468 24.459  55.587 1   33.502  ? 79  HIS A CD2  1 
ATOM   1206 C  CE1  . HIS A 1 90  ? -15.397 23.794  57.453 1   34.192  ? 79  HIS A CE1  1 
ATOM   1207 N  NE2  . HIS A 1 90  ? -14.98  23.363  56.28  1   31.36   ? 79  HIS A NE2  1 
ATOM   1208 H  H    . HIS A 1 90  ? -15.564 27.138  53.809 1   33.914  ? 79  HIS A H    1 
ATOM   1209 H  HA   . HIS A 1 90  ? -16.245 27.791  56.453 1   35.61   ? 79  HIS A HA   1 
ATOM   1210 H  HB2  . HIS A 1 90  ? -13.688 27.065  55.315 1   36.674  ? 79  HIS A HB2  1 
ATOM   1211 H  HB3  . HIS A 1 90  ? -13.89  27.395  56.857 1   36.693  ? 79  HIS A HB3  1 
ATOM   1212 H  HD1  . HIS A 1 90  ? -15.38  25.663  58.206 0   31.69   ? 79  HIS A HD1  1 
ATOM   1213 H  HD2  . HIS A 1 90  ? -14.124 24.43   54.715 1   33.099  ? 79  HIS A HD2  1 
ATOM   1214 H  HE1  . HIS A 1 90  ? -15.761 23.263  58.139 1   32.984  ? 79  HIS A HE1  1 
ATOM   1215 H  HE2  . HIS A 1 90  ? -15.018 22.55   55.976 0   31.65   ? 79  HIS A HE2  1 
ATOM   1216 N  N    . PRO A 1 91  ? -15.281 30.126  56.514 1   35.453  ? 80  PRO A N    1 
ATOM   1217 C  CA   . PRO A 1 91  ? -14.672 31.465  56.485 1   39.495  ? 80  PRO A CA   1 
ATOM   1218 C  C    . PRO A 1 91  ? -13.193 31.405  56.84  1   44.34   ? 80  PRO A C    1 
ATOM   1219 O  O    . PRO A 1 91  ? -12.776 30.52   57.549 1   41.143  ? 80  PRO A O    1 
ATOM   1220 C  CB   . PRO A 1 91  ? -15.466 32.188  57.576 1   40.261  ? 80  PRO A CB   1 
ATOM   1221 C  CG   . PRO A 1 91  ? -15.717 31.102  58.596 1   45.518  ? 80  PRO A CG   1 
ATOM   1222 C  CD   . PRO A 1 91  ? -16.102 29.88   57.716 1   41.344  ? 80  PRO A CD   1 
ATOM   1223 H  HA   . PRO A 1 91  ? -14.812 31.898  55.607 1   39.704  ? 80  PRO A HA   1 
ATOM   1224 H  HB2  . PRO A 1 91  ? -14.942 32.927  57.965 1   41.237  ? 80  PRO A HB2  1 
ATOM   1225 H  HB3  . PRO A 1 91  ? -16.314 32.543  57.22  1   41.223  ? 80  PRO A HB3  1 
ATOM   1226 H  HG2  . PRO A 1 91  ? -14.912 30.917  59.124 1   43.332  ? 80  PRO A HG2  1 
ATOM   1227 H  HG3  . PRO A 1 91  ? -16.449 31.345  59.2   1   43.337  ? 80  PRO A HG3  1 
ATOM   1228 H  HD2  . PRO A 1 91  ? -15.855 29.039  58.154 1   40.629  ? 80  PRO A HD2  1 
ATOM   1229 H  HD3  . PRO A 1 91  ? -17.062 29.878  57.504 1   40.715  ? 80  PRO A HD3  1 
ATOM   1230 N  N    . ASP A 1 92  ? -12.446 32.422  56.443 1   37.696  ? 81  ASP A N    1 
ATOM   1231 C  CA   . ASP A 1 92  ? -11.018 32.481  56.587 1   42.577  ? 81  ASP A CA   1 
ATOM   1232 C  C    . ASP A 1 92  ? -10.605 32.579  58.048 1   43.773  ? 81  ASP A C    1 
ATOM   1233 O  O    . ASP A 1 92  ? -9.515  32.167  58.391 1   43.833  ? 81  ASP A O    1 
ATOM   1234 C  CB   . ASP A 1 92  ? -10.496 33.713  55.88  1   54.065  ? 81  ASP A CB   1 
ATOM   1235 C  CG   . ASP A 1 92  ? -10.401 33.57   54.377 1   60.231  ? 81  ASP A CG   1 
ATOM   1236 O  OD1  . ASP A 1 92  ? -10.622 32.449  53.898 1   67.049  ? 81  ASP A OD1  1 
ATOM   1237 O  OD2  . ASP A 1 92  ? -10.083 34.58   53.738 1   73.613  ? 81  ASP A OD2  1 
ATOM   1238 H  H    . ASP A 1 92  ? -12.866 33.133  56.052 1   40.451  ? 81  ASP A H    1 
ATOM   1239 H  HA   . ASP A 1 92  ? -10.624 31.67   56.194 1   43.843  ? 81  ASP A HA   1 
ATOM   1240 H  HB2  . ASP A 1 92  ? -11.077 34.476  56.083 1   52.267  ? 81  ASP A HB2  1 
ATOM   1241 H  HB3  . ASP A 1 92  ? -9.599  33.92   56.219 1   52.387  ? 81  ASP A HB3  1 
ATOM   1242 N  N    . SER A 1 93  ? -11.402 33.223  58.889 1   39.055  ? 82  SER A N    1 
ATOM   1243 C  CA   . SER A 1 93  ? -11.019 33.295  60.299 1   48.486  ? 82  SER A CA   1 
ATOM   1244 C  C    . SER A 1 93  ? -10.845 31.895  60.913 1   37.265  ? 82  SER A C    1 
ATOM   1245 O  O    . SER A 1 93  ? -9.898  31.727  61.648 1   51.469  ? 82  SER A O    1 
ATOM   1246 C  CB   . SER A 1 93  ? -12.024 34.04   61.093 1   42.59   ? 82  SER A CB   1 
ATOM   1247 O  OG   . SER A 1 93  ? -13.313 33.547  60.788 1   45.679  ? 82  SER A OG   1 
ATOM   1248 H  H    . SER A 1 93  ? -12.172 33.623  58.604 1   42.087  ? 82  SER A H    1 
ATOM   1249 H  HA   . SER A 1 93  ? -10.153 33.773  60.362 1   43.32   ? 82  SER A HA   1 
ATOM   1250 H  HB2  . SER A 1 93  ? -11.842 33.925  62.045 1   44.567  ? 82  SER A HB2  1 
ATOM   1251 H  HB3  . SER A 1 93  ? -11.974 34.99   60.876 1   44.605  ? 82  SER A HB3  1 
ATOM   1252 H  HG   . SER A 1 93  ? -13.878 33.973  61.245 0   45.42   ? 82  SER A HG   1 
ATOM   1253 N  N    . TYR A 1 94  ? -11.757 30.948  60.619 1   36.88   ? 83  TYR A N    1 
ATOM   1254 C  CA   . TYR A 1 94  ? -11.667 29.548  61.074 1   39.319  ? 83  TYR A CA   1 
ATOM   1255 C  C    . TYR A 1 94  ? -10.444 28.851  60.453 1   35.898  ? 83  TYR A C    1 
ATOM   1256 O  O    . TYR A 1 94  ? -9.537  28.34   61.138 1   40.11   ? 83  TYR A O    1 
ATOM   1257 C  CB   . TYR A 1 94  ? -12.962 28.788  60.81  1   35.856  ? 83  TYR A CB   1 
ATOM   1258 C  CG   . TYR A 1 94  ? -12.828 27.285  61.054 1   33.232  ? 83  TYR A CG   1 
ATOM   1259 C  CD1  . TYR A 1 94  ? -12.781 26.797  62.342 1   33.031  ? 83  TYR A CD1  1 
ATOM   1260 C  CD2  . TYR A 1 94  ? -12.737 26.387  60.01  1   30.78   ? 83  TYR A CD2  1 
ATOM   1261 C  CE1  . TYR A 1 94  ? -12.632 25.457  62.603 1   36.229  ? 83  TYR A CE1  1 
ATOM   1262 C  CE2  . TYR A 1 94  ? -12.559 25.026  60.249 1   39.001  ? 83  TYR A CE2  1 
ATOM   1263 C  CZ   . TYR A 1 94  ? -12.493 24.561  61.554 1   35.44   ? 83  TYR A CZ   1 
ATOM   1264 O  OH   . TYR A 1 94  ? -12.353 23.248  61.899 1   37.328  ? 83  TYR A OH   1 
ATOM   1265 H  H    . TYR A 1 94  ? -12.477 31.187  60.11  1   37.555  ? 83  TYR A H    1 
ATOM   1266 H  HA   . TYR A 1 94  ? -11.53  29.567  62.058 1   37.548  ? 83  TYR A HA   1 
ATOM   1267 H  HB2  . TYR A 1 94  ? -13.663 29.147  61.398 1   36.057  ? 83  TYR A HB2  1 
ATOM   1268 H  HB3  . TYR A 1 94  ? -13.233 28.939  59.878 1   36.015  ? 83  TYR A HB3  1 
ATOM   1269 H  HD1  . TYR A 1 94  ? -12.842 27.4    63.066 1   33.845  ? 83  TYR A HD1  1 
ATOM   1270 H  HD2  . TYR A 1 94  ? -12.745 26.705  59.121 1   33.17   ? 83  TYR A HD2  1 
ATOM   1271 H  HE1  . TYR A 1 94  ? -12.587 25.151  63.493 1   35.267  ? 83  TYR A HE1  1 
ATOM   1272 H  HE2  . TYR A 1 94  ? -12.487 24.424  59.529 1   36.063  ? 83  TYR A HE2  1 
ATOM   1273 H  HH   . TYR A 1 94  ? -13.13  22.878  61.948 0   37.06   ? 83  TYR A HH   1 
ATOM   1274 N  N    . LEU A 1 95  ? -10.364 28.923  59.135 1   33.129  ? 84  LEU A N    1 
ATOM   1275 C  CA   . LEU A 1 95  ? -9.273  28.309  58.428 1   33.76   ? 84  LEU A CA   1 
ATOM   1276 C  C    . LEU A 1 95  ? -7.911  28.758  58.919 1   38.313  ? 84  LEU A C    1 
ATOM   1277 O  O    . LEU A 1 95  ? -6.967  27.974  58.87  1   38.065  ? 84  LEU A O    1 
ATOM   1278 C  CB   . LEU A 1 95  ? -9.386  28.531  56.923 1   34.184  ? 84  LEU A CB   1 
ATOM   1279 C  CG   . LEU A 1 95  ? -10.645 27.929  56.314 1   36.762  ? 84  LEU A CG   1 
ATOM   1280 C  CD1  . LEU A 1 95  ? -10.808 28.304  54.815 1   33.046  ? 84  LEU A CD1  1 
ATOM   1281 C  CD2  . LEU A 1 95  ? -10.572 26.367  56.408 1   42.352  ? 84  LEU A CD2  1 
ATOM   1282 H  H    . LEU A 1 95  ? -11.004 29.376  58.664 1   34.002  ? 84  LEU A H    1 
ATOM   1283 H  HA   . LEU A 1 95  ? -9.33   27.336  58.6   1   34.621  ? 84  LEU A HA   1 
ATOM   1284 H  HB2  . LEU A 1 95  ? -9.382  29.5    56.749 1   34.678  ? 84  LEU A HB2  1 
ATOM   1285 H  HB3  . LEU A 1 95  ? -8.601  28.126  56.488 1   34.768  ? 84  LEU A HB3  1 
ATOM   1286 H  HG   . LEU A 1 95  ? -11.436 28.249  56.817 1   36.452  ? 84  LEU A HG   1 
ATOM   1287 H  HD11 . LEU A 1 95  ? -10.865 29.27   54.726 1   34.094  ? 84  LEU A HD11 1 
ATOM   1288 H  HD12 . LEU A 1 95  ? -11.62  27.9    54.465 1   34.138  ? 84  LEU A HD12 1 
ATOM   1289 H  HD13 . LEU A 1 95  ? -10.043 27.978  54.313 1   34.094  ? 84  LEU A HD13 1 
ATOM   1290 H  HD21 . LEU A 1 95  ? -10.76  26.087  57.319 1   40.547  ? 84  LEU A HD21 1 
ATOM   1291 H  HD22 . LEU A 1 95  ? -9.683  26.067  56.154 1   40.577  ? 84  LEU A HD22 1 
ATOM   1292 H  HD23 . LEU A 1 95  ? -11.228 25.974  55.808 1   40.536  ? 84  LEU A HD23 1 
ATOM   1293 N  N    . GLU A 1 96  ? -7.77   30.039  59.258 1   37.906  ? 85  GLU A N    1 
ATOM   1294 C  CA   . GLU A 1 96  ? -6.478  30.611  59.572 1   35.145  ? 85  GLU A CA   1 
ATOM   1295 C  C    . GLU A 1 96  ? -6.084  30.126  60.957 1   33.753  ? 85  GLU A C    1 
ATOM   1296 O  O    . GLU A 1 96  ? -4.892  29.913  61.218 1   33.215  ? 85  GLU A O    1 
ATOM   1297 C  CB   . GLU A 1 96  ? -6.561  32.151  59.443 1   43.766  ? 85  GLU A CB   1 
ATOM   1298 C  CG   . GLU A 1 96  ? -6.317  32.613  57.989 1   52.316  ? 85  GLU A CG   1 
ATOM   1299 C  CD   . GLU A 1 96  ? -6.539  34.093  57.576 1   73.326  ? 85  GLU A CD   1 
ATOM   1300 O  OE1  . GLU A 1 96  ? -6.751  34.876  58.516 1   59.781  ? 85  GLU A OE1  1 
ATOM   1301 O  OE2  . GLU A 1 96  ? -6.57   34.472  56.361 1   66.049  ? 85  GLU A OE2  1 
ATOM   1302 H  H    . GLU A 1 96  ? -8.507  30.578  59.288 1   37.335  ? 85  GLU A H    1 
ATOM   1303 H  HA   . GLU A 1 96  ? -5.817  30.271  58.916 1   36.915  ? 85  GLU A HA   1 
ATOM   1304 H  HB2  . GLU A 1 96  ? -7.439  32.456  59.752 1   43.261  ? 85  GLU A HB2  1 
ATOM   1305 H  HB3  . GLU A 1 96  ? -5.883  32.555  60.025 1   43.285  ? 85  GLU A HB3  1 
ATOM   1306 H  HG2  . GLU A 1 96  ? -5.392  32.384  57.757 1   54.246  ? 85  GLU A HG2  1 
ATOM   1307 H  HG3  . GLU A 1 96  ? -6.881  32.063  57.405 1   54.271  ? 85  GLU A HG3  1 
ATOM   1308 N  N    . ARG A 1 97  ? -7.102  30.027  61.84  1   28.542  ? 86  ARG A N    1 
ATOM   1309 C  CA   . ARG A 1 97  ? -6.9    29.541  63.187 1   36.823  ? 86  ARG A CA   1 
ATOM   1310 C  C    . ARG A 1 97  ? -6.527  28.046  63.133 1   34.993  ? 86  ARG A C    1 
ATOM   1311 O  O    . ARG A 1 97  ? -5.628  27.612  63.83  1   35.668  ? 86  ARG A O    1 
ATOM   1312 C  CB   . ARG A 1 97  ? -8.13   29.926  64.016 1   38.094  ? 86  ARG A CB   1 
ATOM   1313 C  CG   . ARG A 1 97  ? -8.106  31.405  64.466 1   46.753  ? 86  ARG A CG   1 
ATOM   1314 C  CD   . ARG A 1 97  ? -9.234  31.832  65.436 1   44.998  ? 86  ARG A CD   1 
ATOM   1315 N  NE   . ARG A 1 97  ? -10.611 31.489  65.03  1   58.83   ? 86  ARG A NE   1 
ATOM   1316 C  CZ   . ARG A 1 97  ? -11.308 30.365  65.374 1   70.509  ? 86  ARG A CZ   1 
ATOM   1317 N  NH1  . ARG A 1 97  ? -10.94  29.498  66.329 1   64.612  ? 86  ARG A NH1  1 
ATOM   1318 N  NH2  . ARG A 1 97  ? -12.429 30.08   64.736 1   55.049  ? 86  ARG A NH2  1 
ATOM   1319 H  H    . ARG A 1 97  ? -7.941  30.283  61.586 1   31.683  ? 86  ARG A H    1 
ATOM   1320 H  HA   . ARG A 1 97  ? -6.126  30.026  63.57  1   35.019  ? 86  ARG A HA   1 
ATOM   1321 H  HB2  . ARG A 1 97  ? -8.94   29.766  63.486 1   39.443  ? 86  ARG A HB2  1 
ATOM   1322 H  HB3  . ARG A 1 97  ? -8.172  29.352  64.81  1   39.56   ? 86  ARG A HB3  1 
ATOM   1323 H  HG2  . ARG A 1 97  ? -7.242  31.586  64.897 1   44.187  ? 86  ARG A HG2  1 
ATOM   1324 H  HG3  . ARG A 1 97  ? -8.15   31.975  63.668 1   44.272  ? 86  ARG A HG3  1 
ATOM   1325 H  HD2  . ARG A 1 97  ? -9.055  31.432  66.309 1   48.437  ? 86  ARG A HD2  1 
ATOM   1326 H  HD3  . ARG A 1 97  ? -9.175  32.803  65.549 1   48.38   ? 86  ARG A HD3  1 
ATOM   1327 H  HE   . ARG A 1 97  ? -11.024 32.061  64.519 1   57.699  ? 86  ARG A HE   1 
ATOM   1328 H  HH11 . ARG A 1 97  ? -10.419 28.816  66.122 1   66.308  ? 86  ARG A HH11 1 
ATOM   1329 H  HH12 . ARG A 1 97  ? -11.24  29.603  67.154 1   66.356  ? 86  ARG A HH12 1 
ATOM   1330 H  HH21 . ARG A 1 97  ? -12.652 30.535  64.011 1   59.407  ? 86  ARG A HH21 1 
ATOM   1331 H  HH22 . ARG A 1 97  ? -12.953 29.434  65.035 1   59.452  ? 86  ARG A HH22 1 
ATOM   1332 N  N    . PHE A 1 98  ? -7.111  27.3    62.222 1   34.678  ? 87  PHE A N    1 
ATOM   1333 C  CA   . PHE A 1 98  ? -6.83   25.865  62.205 1   36.265  ? 87  PHE A CA   1 
ATOM   1334 C  C    . PHE A 1 98  ? -5.4    25.686  61.715 1   32.92   ? 87  PHE A C    1 
ATOM   1335 O  O    . PHE A 1 98  ? -4.578  25.031  62.297 1   38.422  ? 87  PHE A O    1 
ATOM   1336 C  CB   . PHE A 1 98  ? -7.917  25.27   61.325 1   31.665  ? 87  PHE A CB   1 
ATOM   1337 C  CG   . PHE A 1 98  ? -7.754  23.825  60.929 1   32.957  ? 87  PHE A CG   1 
ATOM   1338 C  CD1  . PHE A 1 98  ? -6.993  22.944  61.69  1   37.755  ? 87  PHE A CD1  1 
ATOM   1339 C  CD2  . PHE A 1 98  ? -8.349  23.368  59.772 1   34.266  ? 87  PHE A CD2  1 
ATOM   1340 C  CE1  . PHE A 1 98  ? -6.826  21.618  61.308 1   38.08   ? 87  PHE A CE1  1 
ATOM   1341 C  CE2  . PHE A 1 98  ? -8.181  22.041  59.375 1   40.13   ? 87  PHE A CE2  1 
ATOM   1342 C  CZ   . PHE A 1 98  ? -7.439  21.164  60.147 1   36      ? 87  PHE A CZ   1 
ATOM   1343 H  H    . PHE A 1 98  ? -7.689  27.662  61.614 1   35.029  ? 87  PHE A H    1 
ATOM   1344 H  HA   . PHE A 1 98  ? -6.915  25.501  63.127 1   34.482  ? 87  PHE A HA   1 
ATOM   1345 H  HB2  . PHE A 1 98  ? -8.776  25.369  61.793 1   33.072  ? 87  PHE A HB2  1 
ATOM   1346 H  HB3  . PHE A 1 98  ? -7.974  25.809  60.505 1   33.017  ? 87  PHE A HB3  1 
ATOM   1347 H  HD1  . PHE A 1 98  ? -6.583  23.251  62.482 1   36.6    ? 87  PHE A HD1  1 
ATOM   1348 H  HD2  . PHE A 1 98  ? -8.858  23.959  59.24  1   35.243  ? 87  PHE A HD2  1 
ATOM   1349 H  HE1  . PHE A 1 98  ? -6.316  21.029  61.841 1   37.498  ? 87  PHE A HE1  1 
ATOM   1350 H  HE2  . PHE A 1 98  ? -8.599  21.732  58.587 1   37.645  ? 87  PHE A HE2  1 
ATOM   1351 H  HZ   . PHE A 1 98  ? -7.335  20.266  59.876 1   37.36   ? 87  PHE A HZ   1 
ATOM   1352 N  N    . LYS A 1 99  ? -5.085  26.388  60.668 1   33.312  ? 88  LYS A N    1 
ATOM   1353 C  CA   . LYS A 1 99  ? -3.783  26.321  60.129 1   33.452  ? 88  LYS A CA   1 
ATOM   1354 C  C    . LYS A 1 99  ? -2.721  26.806  61.111 1   41.949  ? 88  LYS A C    1 
ATOM   1355 O  O    . LYS A 1 99  ? -1.598  26.281  61.088 1   40.846  ? 88  LYS A O    1 
ATOM   1356 C  CB   . LYS A 1 99  ? -3.743  27.095  58.83  1   40.488  ? 88  LYS A CB   1 
ATOM   1357 C  CG   . LYS A 1 99  ? -2.386  26.98   58.156 1   45.422  ? 88  LYS A CG   1 
ATOM   1358 C  CD   . LYS A 1 99  ? -2.445  27.726  56.818 1   58.834  ? 88  LYS A CD   1 
ATOM   1359 C  CE   . LYS A 1 99  ? -1.31   27.415  55.865 1   65.543  ? 88  LYS A CE   1 
ATOM   1360 N  NZ   . LYS A 1 99  ? 0.013   27.3    56.479 1   59.161  ? 88  LYS A NZ   1 
ATOM   1361 H  H    . LYS A 1 99  ? -5.708  26.922  60.266 1   33.329  ? 88  LYS A H    1 
ATOM   1362 H  HA   . LYS A 1 99  ? -3.59   25.372  59.915 1   36.097  ? 88  LYS A HA   1 
ATOM   1363 H  HB2  . LYS A 1 99  ? -4.433  26.751  58.224 1   39.874  ? 88  LYS A HB2  1 
ATOM   1364 H  HB3  . LYS A 1 99  ? -3.934  28.041  59.007 1   39.804  ? 88  LYS A HB3  1 
ATOM   1365 H  HG2  . LYS A 1 99  ? -1.696  27.38   58.728 1   46.851  ? 88  LYS A HG2  1 
ATOM   1366 H  HG3  . LYS A 1 99  ? -2.173  26.033  58.003 1   46.894  ? 88  LYS A HG3  1 
ATOM   1367 H  HD2  . LYS A 1 99  ? -3.295  27.51   56.376 1   56.612  ? 88  LYS A HD2  1 
ATOM   1368 H  HD3  . LYS A 1 99  ? -2.448  28.691  57.001 1   56.811  ? 88  LYS A HD3  1 
ATOM   1369 H  HE2  . LYS A 1 99  ? -1.509  26.578  55.408 1   62.415  ? 88  LYS A HE2  1 
ATOM   1370 H  HE3  . LYS A 1 99  ? -1.273  28.114  55.188 1   62.415  ? 88  LYS A HE3  1 
ATOM   1371 H  HZ1  . LYS A 1 99  ? 0.106   26.483  56.858 1   60.947  ? 88  LYS A HZ1  1 
ATOM   1372 H  HZ2  . LYS A 1 99  ? 0.113   27.937  57.116 1   60.939  ? 88  LYS A HZ2  1 
ATOM   1373 H  HZ3  . LYS A 1 99  ? 0.653   27.409  55.848 1   61.013  ? 88  LYS A HZ3  1 
ATOM   1374 N  N    . ALA A 1 100 ? -3.022  27.84   61.899 1   43.325  ? 89  ALA A N    1 
ATOM   1375 C  CA   . ALA A 1 100 ? -2.066  28.349  62.882 1   43.09   ? 89  ALA A CA   1 
ATOM   1376 C  C    . ALA A 1 100 ? -1.74   27.265  63.894 1   36.942  ? 89  ALA A C    1 
ATOM   1377 O  O    . ALA A 1 100 ? -0.598  27.018  64.176 1   39.609  ? 89  ALA A O    1 
ATOM   1378 C  CB   . ALA A 1 100 ? -2.568  29.557  63.63  1   40.963  ? 89  ALA A CB   1 
ATOM   1379 H  H    . ALA A 1 100 ? -3.838  28.246  61.824 1   42.782  ? 89  ALA A H    1 
ATOM   1380 H  HA   . ALA A 1 100 ? -1.226  28.589  62.403 1   41.53   ? 89  ALA A HA   1 
ATOM   1381 H  HB1  . ALA A 1 100 ? -2.735  30.283  63.004 1   41.569  ? 89  ALA A HB1  1 
ATOM   1382 H  HB2  . ALA A 1 100 ? -3.394  29.337  64.092 1   41.542  ? 89  ALA A HB2  1 
ATOM   1383 H  HB3  . ALA A 1 100 ? -1.903  29.841  64.279 1   41.547  ? 89  ALA A HB3  1 
ATOM   1384 N  N    . ILE A 1 101 ? -2.747  26.707  64.5   1   37.89   ? 90  ILE A N    1 
ATOM   1385 C  CA   . ILE A 1 101 ? -2.539  25.617  65.455 1   44.987  ? 90  ILE A CA   1 
ATOM   1386 C  C    . ILE A 1 101 ? -1.735  24.456  64.846 1   42.825  ? 90  ILE A C    1 
ATOM   1387 O  O    . ILE A 1 101 ? -0.846  23.942  65.494 1   37.955  ? 90  ILE A O    1 
ATOM   1388 C  CB   . ILE A 1 101 ? -3.871  25.083  65.991 1   39.384  ? 90  ILE A CB   1 
ATOM   1389 C  CG1  . ILE A 1 101 ? -4.662  26.132  66.63  1   47.65   ? 90  ILE A CG1  1 
ATOM   1390 C  CG2  . ILE A 1 101 ? -3.603  23.941  66.978 1   48.671  ? 90  ILE A CG2  1 
ATOM   1391 C  CD1  . ILE A 1 101 ? -3.798  26.967  67.592 1   66.678  ? 90  ILE A CD1  1 
ATOM   1392 H  H    . ILE A 1 101 ? -3.598  26.988  64.321 1   39.334  ? 90  ILE A H    1 
ATOM   1393 H  HA   . ILE A 1 101 ? -2.027  25.971  66.206 1   42.379  ? 90  ILE A HA   1 
ATOM   1394 H  HB   . ILE A 1 101 ? -4.385  24.728  65.239 1   43.539  ? 90  ILE A HB   1 
ATOM   1395 H  HG12 . ILE A 1 101 ? -5.042  26.717  65.945 1   48.851  ? 90  ILE A HG12 1 
ATOM   1396 H  HG13 . ILE A 1 101 ? -5.4    25.725  67.128 1   49.025  ? 90  ILE A HG13 1 
ATOM   1397 H  HG21 . ILE A 1 101 ? -4.391  23.79   67.526 1   45.776  ? 90  ILE A HG21 1 
ATOM   1398 H  HG22 . ILE A 1 101 ? -2.853  24.174  67.551 1   45.79   ? 90  ILE A HG22 1 
ATOM   1399 H  HG23 . ILE A 1 101 ? -3.393  23.128  66.49  1   45.7    ? 90  ILE A HG23 1 
ATOM   1400 H  HD11 . ILE A 1 101 ? -3.128  26.405  68.025 1   59.798  ? 90  ILE A HD11 1 
ATOM   1401 H  HD12 . ILE A 1 101 ? -4.368  27.363  68.276 1   60.226  ? 90  ILE A HD12 1 
ATOM   1402 H  HD13 . ILE A 1 101 ? -3.351  27.679  67.096 1   60.051  ? 90  ILE A HD13 1 
ATOM   1403 N  N    . SER A 1 102 ? -2.054  24.047  63.62  1   34.317  ? 91  SER A N    1 
ATOM   1404 C  CA   . SER A 1 102 ? -1.375  22.949  62.929 1   40.74   ? 91  SER A CA   1 
ATOM   1405 C  C    . SER A 1 102 ? 0.112   23.251  62.707 1   40.601  ? 91  SER A C    1 
ATOM   1406 O  O    . SER A 1 102 ? 0.978   22.368  62.805 1   35.003  ? 91  SER A O    1 
ATOM   1407 C  CB   . SER A 1 102 ? -2.138  22.659  61.591 1   33.61   ? 91  SER A CB   1 
ATOM   1408 O  OG   . SER A 1 102 ? -1.419  21.827  60.691 1   35.695  ? 91  SER A OG   1 
ATOM   1409 H  H    . SER A 1 102 ? -2.737  24.472  63.187 1   37.603  ? 91  SER A H    1 
ATOM   1410 H  HA   . SER A 1 102 ? -1.44   22.143  63.502 1   38.041  ? 91  SER A HA   1 
ATOM   1411 H  HB2  . SER A 1 102 ? -2.992  22.235  61.801 1   35.54   ? 91  SER A HB2  1 
ATOM   1412 H  HB3  . SER A 1 102 ? -2.333  23.507  61.149 1   35.576  ? 91  SER A HB3  1 
ATOM   1413 H  HG   . SER A 1 102 ? -1.898  21.717  59.999 0   35.56   ? 91  SER A HG   1 
ATOM   1414 N  N    . ASP A 1 103 ? 0.381   24.501  62.296 1   37.886  ? 92  ASP A N    1 
ATOM   1415 C  CA   . ASP A 1 103 ? 1.696   24.965  61.899 1   36.71   ? 92  ASP A CA   1 
ATOM   1416 C  C    . ASP A 1 103 ? 2.604   25.108  63.112 1   38.267  ? 92  ASP A C    1 
ATOM   1417 O  O    . ASP A 1 103 ? 3.821   25.018  62.995 1   43.822  ? 92  ASP A O    1 
ATOM   1418 C  CB   . ASP A 1 103 ? 1.656   26.312  61.159 1   45.96   ? 92  ASP A CB   1 
ATOM   1419 C  CG   . ASP A 1 103 ? 1.303   26.264  59.672 1   52.029  ? 92  ASP A CG   1 
ATOM   1420 O  OD1  . ASP A 1 103 ? 1.126   25.123  59.134 1   50.513  ? 92  ASP A OD1  1 
ATOM   1421 O  OD2  . ASP A 1 103 ? 1.094   27.358  59.057 1   45.122  ? 92  ASP A OD2  1 
ATOM   1422 H  H    . ASP A 1 103 ? -0.309  25.098  62.258 1   38.32   ? 92  ASP A H    1 
ATOM   1423 H  HA   . ASP A 1 103 ? 2.089   24.295  61.295 1   38.83   ? 92  ASP A HA   1 
ATOM   1424 H  HB2  . ASP A 1 103 ? 1.005   26.893  61.605 1   44.88   ? 92  ASP A HB2  1 
ATOM   1425 H  HB3  . ASP A 1 103 ? 2.535   26.738  61.239 1   44.89   ? 92  ASP A HB3  1 
ATOM   1426 N  N    . ASN A 1 104 ? 1.993   25.358  64.258 1   36.69   ? 93  ASN A N    1 
ATOM   1427 C  CA   . ASN A 1 104 ? 2.731   25.516  65.499 1   46.285  ? 93  ASN A CA   1 
ATOM   1428 C  C    . ASN A 1 104 ? 2.814   24.234  66.335 1   50.427  ? 93  ASN A C    1 
ATOM   1429 O  O    . ASN A 1 104 ? 3.101   24.36   67.499 1   49.702  ? 93  ASN A O    1 
ATOM   1430 C  CB   . ASN A 1 104 ? 2.163   26.669  66.319 1   39.996  ? 93  ASN A CB   1 
ATOM   1431 C  CG   . ASN A 1 104 ? 2.254   27.977  65.52  1   49.203  ? 93  ASN A CG   1 
ATOM   1432 O  OD1  . ASN A 1 104 ? 3.195   28.236  64.765 1   54.622  ? 93  ASN A OD1  1 
ATOM   1433 N  ND2  . ASN A 1 104 ? 1.197   28.766  65.509 1   54.157  ? 93  ASN A ND2  1 
ATOM   1434 H  H    . ASN A 1 104 ? 1.084   25.448  64.275 1   39.045  ? 93  ASN A H    1 
ATOM   1435 H  HA   . ASN A 1 104 ? 3.653   25.766  65.265 1   43.788  ? 93  ASN A HA   1 
ATOM   1436 H  HB2  . ASN A 1 104 ? 1.229   26.484  66.542 1   43.389  ? 93  ASN A HB2  1 
ATOM   1437 H  HB3  . ASN A 1 104 ? 2.667   26.762  67.152 1   43.372  ? 93  ASN A HB3  1 
ATOM   1438 H  HD21 . ASN A 1 104 ? 1.178   29.473  64.973 1   52.553  ? 93  ASN A HD21 1 
ATOM   1439 H  HD22 . ASN A 1 104 ? 0.505   28.593  66.037 1   52.397  ? 93  ASN A HD22 1 
ATOM   1440 N  N    . GLY A 1 105 ? 2.689   23.019  65.768 1   54.278  ? 94  GLY A N    1 
ATOM   1441 C  CA   . GLY A 1 105 ? 2.932   21.79   66.527 1   46.3    ? 94  GLY A CA   1 
ATOM   1442 C  C    . GLY A 1 105 ? 1.643   21.115  67.033 1   46.776  ? 94  GLY A C    1 
ATOM   1443 O  O    . GLY A 1 105 ? 1.711   20.132  67.743 1   55.117  ? 94  GLY A O    1 
ATOM   1444 H  H    . GLY A 1 105 ? 2.447   22.952  64.89  1   51.261  ? 94  GLY A H    1 
ATOM   1445 H  HA2  . GLY A 1 105 ? 3.422   21.159  65.953 1   48.14   ? 94  GLY A HA2  1 
ATOM   1446 H  HA3  . GLY A 1 105 ? 3.511   21.998  67.298 1   48.203  ? 94  GLY A HA3  1 
ATOM   1447 N  N    . GLY A 1 106 ? 0.444   21.637  66.715 1   44.72   ? 95  GLY A N    1 
ATOM   1448 C  CA   . GLY A 1 106 ? -0.775  21.028  67.211 1   40.74   ? 95  GLY A CA   1 
ATOM   1449 C  C    . GLY A 1 106 ? -1.207  21.719  68.493 1   44.528  ? 95  GLY A C    1 
ATOM   1450 O  O    . GLY A 1 106 ? -0.555  22.631  68.937 1   41.105  ? 95  GLY A O    1 
ATOM   1451 H  H    . GLY A 1 106 ? 0.389   22.377  66.182 1   44.329  ? 95  GLY A H    1 
ATOM   1452 H  HA2  . GLY A 1 106 ? -1.483  21.114  66.53  1   42.492  ? 95  GLY A HA2  1 
ATOM   1453 H  HA3  . GLY A 1 106 ? -0.625  20.069  67.38  1   42.505  ? 95  GLY A HA3  1 
ATOM   1454 N  N    . GLY A 1 107 ? -2.316  21.283  69.069 1   39.431  ? 96  GLY A N    1 
ATOM   1455 C  CA   . GLY A 1 107 ? -2.959  22.005  70.141 1   49.483  ? 96  GLY A CA   1 
ATOM   1456 C  C    . GLY A 1 107 ? -4.47   21.812  70.045 1   48.778  ? 96  GLY A C    1 
ATOM   1457 O  O    . GLY A 1 107 ? -4.936  20.779  69.625 1   51.904  ? 96  GLY A O    1 
ATOM   1458 H  H    . GLY A 1 107 ? -2.688  20.499  68.782 1   42.763  ? 96  GLY A H    1 
ATOM   1459 H  HA2  . GLY A 1 107 ? -2.631  21.669  71.008 1   46.714  ? 96  GLY A HA2  1 
ATOM   1460 H  HA3  . GLY A 1 107 ? -2.738  22.963  70.074 1   46.732  ? 96  GLY A HA3  1 
ATOM   1461 N  N    . MET A 1 108 ? -5.216  22.853  70.417 1   60.82   ? 97  MET A N    1 
ATOM   1462 C  CA   . MET A 1 108 ? -6.664  22.816  70.606 1   58.744  ? 97  MET A CA   1 
ATOM   1463 C  C    . MET A 1 108 ? -7.244  23.924  69.713 1   48.016  ? 97  MET A C    1 
ATOM   1464 O  O    . MET A 1 108 ? -6.707  25.052  69.664 1   67.047  ? 97  MET A O    1 
ATOM   1465 C  CB   . MET A 1 108 ? -7.076  23.096  72.078 1   62.46   ? 97  MET A CB   1 
ATOM   1466 C  CG   . MET A 1 108 ? -6.574  22.099  73.117 1   64.859  ? 97  MET A CG   1 
ATOM   1467 S  SD   . MET A 1 108 ? -7.198  20.418  72.836 1   78.125  ? 97  MET A SD   1 
ATOM   1468 C  CE   . MET A 1 108 ? -8.946  20.605  73.208 1   82.797  ? 97  MET A CE   1 
ATOM   1469 H  H    . MET A 1 108 ? -4.791  23.648  70.565 1   57.027  ? 97  MET A H    1 
ATOM   1470 H  HA   . MET A 1 108 ? -7.009  21.936  70.316 1   57.529  ? 97  MET A HA   1 
ATOM   1471 H  HB2  . MET A 1 108 ? -6.748  23.989  72.321 1   62.178  ? 97  MET A HB2  1 
ATOM   1472 H  HB3  . MET A 1 108 ? -8.055  23.125  72.121 1   62.336  ? 97  MET A HB3  1 
ATOM   1473 H  HG2  . MET A 1 108 ? -5.596  22.078  73.098 1   66.585  ? 97  MET A HG2  1 
ATOM   1474 H  HG3  . MET A 1 108 ? -6.851  22.393  74.007 1   66.585  ? 97  MET A HG3  1 
ATOM   1475 H  HE1  . MET A 1 108 ? -9.391  19.742  73.116 1   81.635  ? 97  MET A HE1  1 
ATOM   1476 H  HE2  . MET A 1 108 ? -9.051  20.928  74.122 1   81.593  ? 97  MET A HE2  1 
ATOM   1477 H  HE3  . MET A 1 108 ? -9.343  21.246  72.59  1   81.514  ? 97  MET A HE3  1 
ATOM   1478 N  N    . LEU A 1 109 ? -8.307  23.568  68.977 1   53.315  ? 98  LEU A N    1 
ATOM   1479 C  CA   . LEU A 1 109 ? -9.103  24.5    68.182 1   59.08   ? 98  LEU A CA   1 
ATOM   1480 C  C    . LEU A 1 109 ? -10.442 24.726  68.883 1   69.339  ? 98  LEU A C    1 
ATOM   1481 O  O    . LEU A 1 109 ? -11.447 24.096  68.507 1   64.154  ? 98  LEU A O    1 
ATOM   1482 C  CB   . LEU A 1 109 ? -9.269  23.92   66.78  1   49.427  ? 98  LEU A CB   1 
ATOM   1483 C  CG   . LEU A 1 109 ? -9.775  24.862  65.696 1   54.981  ? 98  LEU A CG   1 
ATOM   1484 C  CD1  . LEU A 1 109 ? -9.014  26.18   65.757 1   60.999  ? 98  LEU A CD1  1 
ATOM   1485 C  CD2  . LEU A 1 109 ? -9.563  24.199  64.341 1   48.709  ? 98  LEU A CD2  1 
ATOM   1486 H  H    . LEU A 1 109 ? -8.551  22.687  68.97  1   53.297  ? 98  LEU A H    1 
ATOM   1487 H  HA   . LEU A 1 109 ? -8.619  25.361  68.128 1   57.878  ? 98  LEU A HA   1 
ATOM   1488 H  HB2  . LEU A 1 109 ? -8.395  23.565  66.495 1   52.757  ? 98  LEU A HB2  1 
ATOM   1489 H  HB3  . LEU A 1 109 ? -9.883  23.153  66.835 1   52.884  ? 98  LEU A HB3  1 
ATOM   1490 H  HG   . LEU A 1 109 ? -10.742 25.03   65.836 1   53.738  ? 98  LEU A HG   1 
ATOM   1491 H  HD11 . LEU A 1 109 ? -9.381  26.736  66.464 1   59.164  ? 98  LEU A HD11 1 
ATOM   1492 H  HD12 . LEU A 1 109 ? -9.099  26.643  64.906 1   59.083  ? 98  LEU A HD12 1 
ATOM   1493 H  HD13 . LEU A 1 109 ? -8.074  26.007  65.936 1   59.081  ? 98  LEU A HD13 1 
ATOM   1494 H  HD21 . LEU A 1 109 ? -9.952  23.308  64.351 1   50.439  ? 98  LEU A HD21 1 
ATOM   1495 H  HD22 . LEU A 1 109 ? -8.611  24.134  64.156 1   50.443  ? 98  LEU A HD22 1 
ATOM   1496 H  HD23 . LEU A 1 109 ? -9.991  24.731  63.65  1   50.321  ? 98  LEU A HD23 1 
ATOM   1497 N  N    . GLY A 1 110 ? -10.39  25.586  69.936 1   81.799  ? 99  GLY A N    1 
ATOM   1498 C  CA   . GLY A 1 110 ? -11.377 25.643  71.008 1   83.393  ? 99  GLY A CA   1 
ATOM   1499 C  C    . GLY A 1 110 ? -11.43  24.301  71.738 1   80.142  ? 99  GLY A C    1 
ATOM   1500 O  O    . GLY A 1 110 ? -10.715 23.374  71.371 1   80.765  ? 99  GLY A O    1 
ATOM   1501 H  H    . GLY A 1 110 ? -9.687  26.169  69.975 1   78.622  ? 99  GLY A H    1 
ATOM   1502 H  HA2  . GLY A 1 110 ? -11.133 26.36   71.64  1   82.283  ? 99  GLY A HA2  1 
ATOM   1503 H  HA3  . GLY A 1 110 ? -12.262 25.853  70.628 1   82.283  ? 99  GLY A HA3  1 
ATOM   1504 N  N    . LYS A 1 111 ? -12.267 24.185  72.774 1   102.854 ? 100 LYS A N    1 
ATOM   1505 C  CA   . LYS A 1 111 ? -12.218 23.018  73.65  1   124.439 ? 100 LYS A CA   1 
ATOM   1506 C  C    . LYS A 1 111 ? -12.803 21.78   72.935 1   113.02  ? 100 LYS A C    1 
ATOM   1507 O  O    . LYS A 1 111 ? -13.584 21.865  71.97  1   74.566  ? 100 LYS A O    1 
ATOM   1508 C  CB   . LYS A 1 111 ? -12.827 23.448  74.995 1   145.231 ? 100 LYS A CB   1 
ATOM   1509 C  CG   . LYS A 1 111 ? -12.546 22.544  76.209 1   148.787 ? 100 LYS A CG   1 
ATOM   1510 C  CD   . LYS A 1 111 ? -13.714 22.476  77.192 1   137.681 ? 100 LYS A CD   1 
ATOM   1511 C  CE   . LYS A 1 111 ? -14.894 21.725  76.619 1   117.526 ? 100 LYS A CE   1 
ATOM   1512 N  NZ   . LYS A 1 111 ? -16.161 22.337  77.02  1   97.96   ? 100 LYS A NZ   1 
ATOM   1513 H  H    . LYS A 1 111 ? -12.881 24.841  72.938 1   101.498 ? 100 LYS A H    1 
ATOM   1514 H  HA   . LYS A 1 111 ? -11.263 22.825  73.832 1   120.68  ? 100 LYS A HA   1 
ATOM   1515 H  HB2  . LYS A 1 111 ? -12.495 24.347  75.206 1   140.331 ? 100 LYS A HB2  1 
ATOM   1516 H  HB3  . LYS A 1 111 ? -13.799 23.517  74.881 1   140.524 ? 100 LYS A HB3  1 
ATOM   1517 H  HG2  . LYS A 1 111 ? -12.344 21.64   75.889 1   144.905 ? 100 LYS A HG2  1 
ATOM   1518 H  HG3  . LYS A 1 111 ? -11.753 22.884  76.677 1   145.295 ? 100 LYS A HG3  1 
ATOM   1519 H  HD2  . LYS A 1 111 ? -13.418 22.028  78.014 1   135     ? 100 LYS A HD2  1 
ATOM   1520 H  HD3  . LYS A 1 111 ? -13.994 23.388  77.424 1   134.581 ? 100 LYS A HD3  1 
ATOM   1521 H  HE2  . LYS A 1 111 ? -14.846 21.708  75.646 1   117.058 ? 100 LYS A HE2  1 
ATOM   1522 H  HE3  . LYS A 1 111 ? -14.875 20.804  76.936 1   116.732 ? 100 LYS A HE3  1 
ATOM   1523 H  HZ1  . LYS A 1 111 ? -16.165 23.217  76.803 1   103.99  ? 100 LYS A HZ1  1 
ATOM   1524 H  HZ2  . LYS A 1 111 ? -16.275 22.248  77.915 1   103.702 ? 100 LYS A HZ2  1 
ATOM   1525 H  HZ3  . LYS A 1 111 ? -16.847 21.924  76.592 1   103.702 ? 100 LYS A HZ3  1 
ATOM   1526 N  N    . GLU A 1 112 ? -12.368 20.592  73.379 1   110.985 ? 101 GLU A N    1 
ATOM   1527 C  CA   . GLU A 1 112 ? -12.661 19.369  72.649 1   122.586 ? 101 GLU A CA   1 
ATOM   1528 C  C    . GLU A 1 112 ? -12.624 19.68   71.145 1   120.03  ? 101 GLU A C    1 
ATOM   1529 O  O    . GLU A 1 112 ? -13.675 19.835  70.516 1   132.903 ? 101 GLU A O    1 
ATOM   1530 C  CB   . GLU A 1 112 ? -14.023 18.799  73.058 1   132.016 ? 101 GLU A CB   1 
ATOM   1531 C  CG   . GLU A 1 112 ? -14.154 18.236  74.473 1   132.678 ? 101 GLU A CG   1 
ATOM   1532 C  CD   . GLU A 1 112 ? -15.583 17.732  74.693 1   136.759 ? 101 GLU A CD   1 
ATOM   1533 O  OE1  . GLU A 1 112 ? -16.012 16.789  73.958 1   109.599 ? 101 GLU A OE1  1 
ATOM   1534 O  OE2  . GLU A 1 112 ? -16.296 18.312  75.56  1   101.167 ? 101 GLU A OE2  1 
ATOM   1535 H  H    . GLU A 1 112 ? -11.866 20.545  74.141 1   114.365 ? 101 GLU A H    1 
ATOM   1536 H  HA   . GLU A 1 112 ? -11.956 18.704  72.855 1   121.387 ? 101 GLU A HA   1 
ATOM   1537 H  HB2  . GLU A 1 112 ? -14.704 19.492  72.933 1   129.845 ? 101 GLU A HB2  1 
ATOM   1538 H  HB3  . GLU A 1 112 ? -14.235 18.062  72.456 1   129.349 ? 101 GLU A HB3  1 
ATOM   1539 H  HG2  . GLU A 1 112 ? -13.525 17.493  74.595 1   133.396 ? 101 GLU A HG2  1 
ATOM   1540 H  HG3  . GLU A 1 112 ? -13.952 18.936  75.13  1   133.212 ? 101 GLU A HG3  1 
ATOM   1541 N  N    . ALA A 1 113 ? -11.397 19.895  70.628 1   85.059  ? 102 ALA A N    1 
ATOM   1542 C  CA   . ALA A 1 113 ? -11.022 19.848  69.211 1   74.763  ? 102 ALA A CA   1 
ATOM   1543 C  C    . ALA A 1 113 ? -9.488  19.767  69.107 1   56.383  ? 102 ALA A C    1 
ATOM   1544 O  O    . ALA A 1 113 ? -8.777  20.785  68.93  1   51.897  ? 102 ALA A O    1 
ATOM   1545 C  CB   . ALA A 1 113 ? -11.576 21.046  68.477 1   76.254  ? 102 ALA A CB   1 
ATOM   1546 H  H    . ALA A 1 113 ? -10.734 20.089  71.225 1   89.558  ? 102 ALA A H    1 
ATOM   1547 H  HA   . ALA A 1 113 ? -11.407 19.024  68.813 1   72.996  ? 102 ALA A HA   1 
ATOM   1548 H  HB1  . ALA A 1 113 ? -12.528 20.924  68.323 1   75.972  ? 102 ALA A HB1  1 
ATOM   1549 H  HB2  . ALA A 1 113 ? -11.438 21.844  69.012 1   75.719  ? 102 ALA A HB2  1 
ATOM   1550 H  HB3  . ALA A 1 113 ? -11.122 21.147  67.623 1   75.619  ? 102 ALA A HB3  1 
ATOM   1551 N  N    . PRO A 1 114 ? -8.911  18.565  69.322 1   56.108  ? 103 PRO A N    1 
ATOM   1552 C  CA   . PRO A 1 114 ? -7.448  18.406  69.464 1   49.702  ? 103 PRO A CA   1 
ATOM   1553 C  C    . PRO A 1 114 ? -6.897  18.005  68.1   1   40.195  ? 103 PRO A C    1 
ATOM   1554 O  O    . PRO A 1 114 ? -7.449  17.113  67.442 1   38.241  ? 103 PRO A O    1 
ATOM   1555 C  CB   . PRO A 1 114 ? -7.398  17.228  70.451 1   51.724  ? 103 PRO A CB   1 
ATOM   1556 C  CG   . PRO A 1 114 ? -8.574  16.345  69.996 1   60.9    ? 103 PRO A CG   1 
ATOM   1557 C  CD   . PRO A 1 114 ? -9.615  17.266  69.325 1   57.73   ? 103 PRO A CD   1 
ATOM   1558 H  HA   . PRO A 1 114 ? -7.01   19.213  69.83  1   49.269  ? 103 PRO A HA   1 
ATOM   1559 H  HB2  . PRO A 1 114 ? -6.542  16.744  70.381 1   52.99   ? 103 PRO A HB2  1 
ATOM   1560 H  HB3  . PRO A 1 114 ? -7.523  17.538  71.378 1   53.131  ? 103 PRO A HB3  1 
ATOM   1561 H  HG2  . PRO A 1 114 ? -8.266  15.664  69.363 1   57.822  ? 103 PRO A HG2  1 
ATOM   1562 H  HG3  . PRO A 1 114 ? -8.974  15.889  70.766 1   57.972  ? 103 PRO A HG3  1 
ATOM   1563 H  HD2  . PRO A 1 114 ? -9.823  16.968  68.412 1   57.991  ? 103 PRO A HD2  1 
ATOM   1564 H  HD3  . PRO A 1 114 ? -10.441 17.307  69.854 1   58.542  ? 103 PRO A HD3  1 
ATOM   1565 N  N    . LEU A 1 115 ? -5.796  18.622  67.714 1   38.696  ? 104 LEU A N    1 
ATOM   1566 C  CA   . LEU A 1 115 ? -5.151  18.282  66.467 1   43.067  ? 104 LEU A CA   1 
ATOM   1567 C  C    . LEU A 1 115 ? -3.654  18.253  66.635 1   38.327  ? 104 LEU A C    1 
ATOM   1568 O  O    . LEU A 1 115 ? -3.087  18.604  67.643 1   37.937  ? 104 LEU A O    1 
ATOM   1569 C  CB   . LEU A 1 115 ? -5.579  19.275  65.402 1   38.671  ? 104 LEU A CB   1 
ATOM   1570 C  CG   . LEU A 1 115 ? -5.094  20.722  65.551 1   39.346  ? 104 LEU A CG   1 
ATOM   1571 C  CD1  . LEU A 1 115 ? -4.234  21.29   64.423 1   42.465  ? 104 LEU A CD1  1 
ATOM   1572 C  CD2  . LEU A 1 115 ? -6.304  21.555  65.642 1   47.247  ? 104 LEU A CD2  1 
ATOM   1573 H  H    . LEU A 1 115 ? -5.432  19.276  68.239 1   40.126  ? 104 LEU A H    1 
ATOM   1574 H  HA   . LEU A 1 115 ? -5.447  17.376  66.198 1   40.456  ? 104 LEU A HA   1 
ATOM   1575 H  HB2  . LEU A 1 115 ? -5.269  18.936  64.53  1   39.804  ? 104 LEU A HB2  1 
ATOM   1576 H  HB3  . LEU A 1 115 ? -6.564  19.275  65.367 1   39.907  ? 104 LEU A HB3  1 
ATOM   1577 H  HG   . LEU A 1 115 ? -4.593  20.803  66.403 1   41.202  ? 104 LEU A HG   1 
ATOM   1578 H  HD11 . LEU A 1 115 ? -3.376  20.834  64.409 1   41.536  ? 104 LEU A HD11 1 
ATOM   1579 H  HD12 . LEU A 1 115 ? -4.092  22.24   64.566 1   41.6    ? 104 LEU A HD12 1 
ATOM   1580 H  HD13 . LEU A 1 115 ? -4.685  21.156  63.573 1   41.514  ? 104 LEU A HD13 1 
ATOM   1581 H  HD21 . LEU A 1 115 ? -6.851  21.255  66.387 1   44.586  ? 104 LEU A HD21 1 
ATOM   1582 H  HD22 . LEU A 1 115 ? -6.813  21.482  64.817 1   44.587  ? 104 LEU A HD22 1 
ATOM   1583 H  HD23 . LEU A 1 115 ? -6.05   22.482  65.783 1   44.616  ? 104 LEU A HD23 1 
ATOM   1584 N  N    . GLY A 1 116 ? -2.994  17.787  65.618 1   36.726  ? 105 GLY A N    1 
ATOM   1585 C  CA   . GLY A 1 116 ? -1.57   17.626  65.764 1   30.147  ? 105 GLY A CA   1 
ATOM   1586 C  C    . GLY A 1 116 ? -0.813  18.373  64.694 1   33.066  ? 105 GLY A C    1 
ATOM   1587 O  O    . GLY A 1 116 ? -1.369  19.054  63.845 1   34.277  ? 105 GLY A O    1 
ATOM   1588 H  H    . GLY A 1 116 ? -3.408  17.561  64.834 1   35.582  ? 105 GLY A H    1 
ATOM   1589 H  HA2  . GLY A 1 116 ? -1.291  17.949  66.651 1   32.465  ? 105 GLY A HA2  1 
ATOM   1590 H  HA3  . GLY A 1 116 ? -1.355  16.666  65.71  1   32.406  ? 105 GLY A HA3  1 
ATOM   1591 N  N    . PRO A 1 117 ? 0.507   18.255  64.729 1   32.18   ? 106 PRO A N    1 
ATOM   1592 C  CA   . PRO A 1 117 ? 1.332   18.988  63.794 1   36.631  ? 106 PRO A CA   1 
ATOM   1593 C  C    . PRO A 1 117 ? 1.009   18.496  62.384 1   35.415  ? 106 PRO A C    1 
ATOM   1594 O  O    . PRO A 1 117 ? 0.832   17.311  62.152 1   31.697  ? 106 PRO A O    1 
ATOM   1595 C  CB   . PRO A 1 117 ? 2.768   18.644  64.24  1   39.552  ? 106 PRO A CB   1 
ATOM   1596 C  CG   . PRO A 1 117 ? 2.579   17.39   65.084 1   48.735  ? 106 PRO A CG   1 
ATOM   1597 C  CD   . PRO A 1 117 ? 1.218   17.432  65.718 1   42.853  ? 106 PRO A CD   1 
ATOM   1598 H  HA   . PRO A 1 117 ? 1.166   19.959  63.879 1   35.968  ? 106 PRO A HA   1 
ATOM   1599 H  HB2  . PRO A 1 117 ? 3.348   18.464  63.463 1   40.742  ? 106 PRO A HB2  1 
ATOM   1600 H  HB3  . PRO A 1 117 ? 3.158   19.373  64.773 1   40.812  ? 106 PRO A HB3  1 
ATOM   1601 H  HG2  . PRO A 1 117 ? 2.662   16.591  64.523 1   45.141  ? 106 PRO A HG2  1 
ATOM   1602 H  HG3  . PRO A 1 117 ? 3.269   17.346  65.778 1   45.138  ? 106 PRO A HG3  1 
ATOM   1603 H  HD2  . PRO A 1 117 ? 0.831   16.532  65.793 1   41.148  ? 106 PRO A HD2  1 
ATOM   1604 H  HD3  . PRO A 1 117 ? 1.243   17.863  66.601 1   41.312  ? 106 PRO A HD3  1 
ATOM   1605 N  N    . GLY A 1 118 ? 0.896   19.444  61.474 1   35.402  ? 107 GLY A N    1 
ATOM   1606 C  CA   . GLY A 1 118 ? 0.593   19.17   60.073 1   34.848  ? 107 GLY A CA   1 
ATOM   1607 C  C    . GLY A 1 118 ? -0.873  18.737  59.825 1   30.371  ? 107 GLY A C    1 
ATOM   1608 O  O    . GLY A 1 118 ? -1.174  18.346  58.705 1   31.017  ? 107 GLY A O    1 
ATOM   1609 H  H    . GLY A 1 118 ? 1.014   20.314  61.727 1   35.295  ? 107 GLY A H    1 
ATOM   1610 H  HA2  . GLY A 1 118 ? 0.783   19.981  59.546 1   33.944  ? 107 GLY A HA2  1 
ATOM   1611 H  HA3  . GLY A 1 118 ? 1.198   18.46   59.753 1   33.976  ? 107 GLY A HA3  1 
ATOM   1612 N  N    . SER A 1 119 ? -1.773  18.758  60.829 1   31.702  ? 108 SER A N    1 
ATOM   1613 C  CA   . SER A 1 119 ? -3.141  18.29   60.627 1   27.964  ? 108 SER A CA   1 
ATOM   1614 C  C    . SER A 1 119 ? -3.89   19.084  59.555 1   31.696  ? 108 SER A C    1 
ATOM   1615 O  O    . SER A 1 119 ? -4.866  18.598  58.967 1   28.288  ? 108 SER A O    1 
ATOM   1616 C  CB   . SER A 1 119 ? -3.972  18.309  61.887 1   27.982  ? 108 SER A CB   1 
ATOM   1617 O  OG   . SER A 1 119 ? -3.608  17.272  62.795 1   31.209  ? 108 SER A OG   1 
ATOM   1618 H  H    . SER A 1 119 ? -1.534  19.08   61.649 1   30.549  ? 108 SER A H    1 
ATOM   1619 H  HA   . SER A 1 119 ? -3.088  17.351  60.317 1   29.331  ? 108 SER A HA   1 
ATOM   1620 H  HB2  . SER A 1 119 ? -3.864  19.173  62.327 1   28.717  ? 108 SER A HB2  1 
ATOM   1621 H  HB3  . SER A 1 119 ? -4.914  18.21   61.65  1   28.729  ? 108 SER A HB3  1 
ATOM   1622 H  HG   . SER A 1 119 ? -4.096  17.332  63.484 0   30.73   ? 108 SER A HG   1 
ATOM   1623 N  N    . TYR A 1 120 ? -3.579  20.396  59.405 1   31.578  ? 109 TYR A N    1 
ATOM   1624 C  CA   . TYR A 1 120 ? -4.231  21.185  58.38  1   29.477  ? 109 TYR A CA   1 
ATOM   1625 C  C    . TYR A 1 120 ? -4.091  20.55   56.996 1   30.091  ? 109 TYR A C    1 
ATOM   1626 O  O    . TYR A 1 120 ? -5.078  20.41   56.278 1   32.746  ? 109 TYR A O    1 
ATOM   1627 C  CB   . TYR A 1 120 ? -3.684  22.614  58.379 1   30.831  ? 109 TYR A CB   1 
ATOM   1628 C  CG   . TYR A 1 120 ? -4.34   23.522  57.375 1   29.191  ? 109 TYR A CG   1 
ATOM   1629 C  CD1  . TYR A 1 120 ? -5.557  24.11   57.678 1   36.222  ? 109 TYR A CD1  1 
ATOM   1630 C  CD2  . TYR A 1 120 ? -3.766  23.744  56.128 1   32.066  ? 109 TYR A CD2  1 
ATOM   1631 C  CE1  . TYR A 1 120 ? -6.159  24.956  56.78  1   37.358  ? 109 TYR A CE1  1 
ATOM   1632 C  CE2  . TYR A 1 120 ? -4.368  24.599  55.207 1   33.912  ? 109 TYR A CE2  1 
ATOM   1633 C  CZ   . TYR A 1 120 ? -5.564  25.202  55.546 1   43.362  ? 109 TYR A CZ   1 
ATOM   1634 O  OH   . TYR A 1 120 ? -6.216  26.016  54.675 1   42.31   ? 109 TYR A OH   1 
ATOM   1635 H  H    . TYR A 1 120 ? -2.955  20.788  59.945 1   31.143  ? 109 TYR A H    1 
ATOM   1636 H  HA   . TYR A 1 120 ? -5.198  21.229  58.6   1   30.265  ? 109 TYR A HA   1 
ATOM   1637 H  HB2  . TYR A 1 120 ? -3.804  22.994  59.277 1   30.154  ? 109 TYR A HB2  1 
ATOM   1638 H  HB3  . TYR A 1 120 ? -2.72   22.578  58.193 1   30.15   ? 109 TYR A HB3  1 
ATOM   1639 H  HD1  . TYR A 1 120 ? -5.951  23.966  58.523 1   34.728  ? 109 TYR A HD1  1 
ATOM   1640 H  HD2  . TYR A 1 120 ? -2.937  23.343  55.918 1   31.919  ? 109 TYR A HD2  1 
ATOM   1641 H  HE1  . TYR A 1 120 ? -6.98   25.365  56.995 1   38.259  ? 109 TYR A HE1  1 
ATOM   1642 H  HE2  . TYR A 1 120 ? -3.972  24.758  54.367 1   35.444  ? 109 TYR A HE2  1 
ATOM   1643 H  HH   . TYR A 1 120 ? -5.976  26.826  54.806 0   41.96   ? 109 TYR A HH   1 
ATOM   1644 N  N    . GLU A 1 121 ? -2.87   20.263  56.589 1   28.854  ? 110 GLU A N    1 
ATOM   1645 C  CA   . GLU A 1 121 ? -2.579  19.786  55.246 1   33.745  ? 110 GLU A CA   1 
ATOM   1646 C  C    . GLU A 1 121 ? -3.137  18.375  55.124 1   31.991  ? 110 GLU A C    1 
ATOM   1647 O  O    . GLU A 1 121 ? -3.584  17.978  54.063 1   33.318  ? 110 GLU A O    1 
ATOM   1648 C  CB   . GLU A 1 121 ? -1.072  19.685  54.922 1   44.76   ? 110 GLU A CB   1 
ATOM   1649 C  CG   . GLU A 1 121 ? -0.388  21.044  54.687 1   49.86   ? 110 GLU A CG   1 
ATOM   1650 C  CD   . GLU A 1 121 ? -0.086  21.958  55.885 1   48.15   ? 110 GLU A CD   1 
ATOM   1651 O  OE1  . GLU A 1 121 ? 0.02    21.445  57.035 1   41.808  ? 110 GLU A OE1  1 
ATOM   1652 O  OE2  . GLU A 1 121 ? -0.143  23.193  55.693 1   57      ? 110 GLU A OE2  1 
ATOM   1653 H  H    . GLU A 1 121 ? -2.175  20.368  57.172 1   30.348  ? 110 GLU A H    1 
ATOM   1654 H  HA   . GLU A 1 121 ? -3.03   20.377  54.589 1   34.069  ? 110 GLU A HA   1 
ATOM   1655 H  HB2  . GLU A 1 121 ? -0.622  19.227  55.663 1   42.995  ? 110 GLU A HB2  1 
ATOM   1656 H  HB3  . GLU A 1 121 ? -0.957  19.135  54.119 1   42.945  ? 110 GLU A HB3  1 
ATOM   1657 H  HG2  . GLU A 1 121 ? 0.461   20.878  54.224 1   48.275  ? 110 GLU A HG2  1 
ATOM   1658 H  HG3  . GLU A 1 121 ? -0.943  21.556  54.06  1   48.316  ? 110 GLU A HG3  1 
ATOM   1659 N  N    . ILE A 1 122 ? -3.229  17.639  56.223 1   28.896  ? 111 ILE A N    1 
ATOM   1660 C  CA   . ILE A 1 122 ? -3.81   16.299  56.124 1   32.069  ? 111 ILE A CA   1 
ATOM   1661 C  C    . ILE A 1 122 ? -5.344  16.336  56.034 1   31.434  ? 111 ILE A C    1 
ATOM   1662 O  O    . ILE A 1 122 ? -5.952  15.609  55.253 1   29.635  ? 111 ILE A O    1 
ATOM   1663 C  CB   . ILE A 1 122 ? -3.371  15.4    57.267 1   29.999  ? 111 ILE A CB   1 
ATOM   1664 C  CG1  . ILE A 1 122 ? -1.891  15.183  57.132 1   33.28   ? 111 ILE A CG1  1 
ATOM   1665 C  CG2  . ILE A 1 122 ? -4.167  14.098  57.227 1   29.404  ? 111 ILE A CG2  1 
ATOM   1666 C  CD1  . ILE A 1 122 ? -1.224  14.741  58.403 1   34.744  ? 111 ILE A CD1  1 
ATOM   1667 H  H    . ILE A 1 122 ? -2.925  17.945  57.029 1   30.315  ? 111 ILE A H    1 
ATOM   1668 H  HA   . ILE A 1 122 ? -3.478  15.896  55.298 1   30.957  ? 111 ILE A HA   1 
ATOM   1669 H  HB   . ILE A 1 122 ? -3.547  15.857  58.113 1   30.88   ? 111 ILE A HB   1 
ATOM   1670 H  HG12 . ILE A 1 122 ? -1.735  14.505  56.443 1   32.791  ? 111 ILE A HG12 1 
ATOM   1671 H  HG13 . ILE A 1 122 ? -1.473  16.016  56.832 1   32.785  ? 111 ILE A HG13 1 
ATOM   1672 H  HG21 . ILE A 1 122 ? -3.687  13.408  57.715 1   29.655  ? 111 ILE A HG21 1 
ATOM   1673 H  HG22 . ILE A 1 122 ? -4.286  13.814  56.305 1   29.61   ? 111 ILE A HG22 1 
ATOM   1674 H  HG23 . ILE A 1 122 ? -5.038  14.233  57.639 1   29.607  ? 111 ILE A HG23 1 
ATOM   1675 H  HD11 . ILE A 1 122 ? -1.365  15.413  59.097 1   34.293  ? 111 ILE A HD11 1 
ATOM   1676 H  HD12 . ILE A 1 122 ? -0.266  14.633  58.248 1   34.293  ? 111 ILE A HD12 1 
ATOM   1677 H  HD13 . ILE A 1 122 ? -1.603  13.89   58.695 1   34.267  ? 111 ILE A HD13 1 
ATOM   1678 N  N    . ALA A 1 123 ? -5.971  17.279  56.713 1   32.309  ? 112 ALA A N    1 
ATOM   1679 C  CA   . ALA A 1 123 ? -7.398  17.519  56.527 1   29.459  ? 112 ALA A CA   1 
ATOM   1680 C  C    . ALA A 1 123 ? -7.731  17.96   55.092 1   29.662  ? 112 ALA A C    1 
ATOM   1681 O  O    . ALA A 1 123 ? -8.714  17.491  54.519 1   32.892  ? 112 ALA A O    1 
ATOM   1682 C  CB   . ALA A 1 123 ? -7.839  18.522  57.565 1   27.815  ? 112 ALA A CB   1 
ATOM   1683 H  H    . ALA A 1 123 ? -5.51   17.788  57.316 1   31.399  ? 112 ALA A H    1 
ATOM   1684 H  HA   . ALA A 1 123 ? -7.875  16.661  56.696 1   29.729  ? 112 ALA A HA   1 
ATOM   1685 H  HB1  . ALA A 1 123 ? -7.671  18.167  58.455 1   28.293  ? 112 ALA A HB1  1 
ATOM   1686 H  HB2  . ALA A 1 123 ? -7.344  19.35   57.451 1   28.293  ? 112 ALA A HB2  1 
ATOM   1687 H  HB3  . ALA A 1 123 ? -8.789  18.7    57.465 1   28.293  ? 112 ALA A HB3  1 
ATOM   1688 N  N    . CYS A 1 124 ? -6.914  18.815  54.472 1   31.676  ? 113 CYS A N    1 
ATOM   1689 C  CA   . CYS A 1 124 ? -7.148  19.208  53.08  1   33.62   ? 113 CYS A CA   1 
ATOM   1690 C  C    . CYS A 1 124 ? -7.068  18.001  52.14  1   33.74   ? 113 CYS A C    1 
ATOM   1691 O  O    . CYS A 1 124 ? -7.769  17.901  51.159 1   34.701  ? 113 CYS A O    1 
ATOM   1692 C  CB   . CYS A 1 124 ? -6.159  20.279  52.612 1   34.84   ? 113 CYS A CB   1 
ATOM   1693 S  SG   . CYS A 1 124 ? -6.305  21.858  53.516 1   36.832  ? 113 CYS A SG   1 
ATOM   1694 H  H    . CYS A 1 124 ? -6.198  19.167  54.919 1   31.61   ? 113 CYS A H    1 
ATOM   1695 H  HA   . CYS A 1 124 ? -8.061  19.587  53.022 1   33.469  ? 113 CYS A HA   1 
ATOM   1696 H  HB2  . CYS A 1 124 ? -5.243  19.94   52.722 1   34.907  ? 113 CYS A HB2  1 
ATOM   1697 H  HB3  . CYS A 1 124 ? -6.304  20.453  51.655 1   34.902  ? 113 CYS A HB3  1 
ATOM   1698 H  HG   . CYS A 1 124 ? -5.438  22.47   52.929 0   36.75   ? 113 CYS A HG   1 
ATOM   1699 N  N    . LEU A 1 125 ? -6.102  17.137  52.339 1   38.329  ? 114 LEU A N    1 
ATOM   1700 C  CA   . LEU A 1 125 ? -6.052  15.894  51.592 1   36.639  ? 114 LEU A CA   1 
ATOM   1701 C  C    . LEU A 1 125 ? -7.301  15.038  51.768 1   31.409  ? 114 LEU A C    1 
ATOM   1702 O  O    . LEU A 1 125 ? -7.801  14.463  50.817 1   36.283  ? 114 LEU A O    1 
ATOM   1703 C  CB   . LEU A 1 125 ? -4.81   15.158  52.035 1   32.884  ? 114 LEU A CB   1 
ATOM   1704 C  CG   . LEU A 1 125 ? -4.502  13.85   51.303 1   36.955  ? 114 LEU A CG   1 
ATOM   1705 C  CD1  . LEU A 1 125 ? -4.528  13.941  49.755 1   41.293  ? 114 LEU A CD1  1 
ATOM   1706 C  CD2  . LEU A 1 125 ? -3.069  13.423  51.733 1   40.529  ? 114 LEU A CD2  1 
ATOM   1707 H  H    . LEU A 1 125 ? -5.448  17.317  52.951 1   36.701  ? 114 LEU A H    1 
ATOM   1708 H  HA   . LEU A 1 125 ? -5.965  16.119  50.632 1   35.287  ? 114 LEU A HA   1 
ATOM   1709 H  HB2  . LEU A 1 125 ? -4.04   15.763  51.925 1   34.687  ? 114 LEU A HB2  1 
ATOM   1710 H  HB3  . LEU A 1 125 ? -4.896  14.961  52.996 1   34.604  ? 114 LEU A HB3  1 
ATOM   1711 H  HG   . LEU A 1 125 ? -5.146  13.156  51.599 1   37.495  ? 114 LEU A HG   1 
ATOM   1712 H  HD11 . LEU A 1 125 ? -5.439  14.097  49.454 1   39.935  ? 114 LEU A HD11 1 
ATOM   1713 H  HD12 . LEU A 1 125 ? -4.2    13.109  49.375 1   39.973  ? 114 LEU A HD12 1 
ATOM   1714 H  HD13 . LEU A 1 125 ? -3.961  14.675  49.463 1   39.973  ? 114 LEU A HD13 1 
ATOM   1715 H  HD21 . LEU A 1 125 ? -3.034  13.332  52.7   1   39.447  ? 114 LEU A HD21 1 
ATOM   1716 H  HD22 . LEU A 1 125 ? -2.43   14.098  51.449 1   39.42   ? 114 LEU A HD22 1 
ATOM   1717 H  HD23 . LEU A 1 125 ? -2.846  12.573  51.32  1   39.426  ? 114 LEU A HD23 1 
ATOM   1718 N  N    . SER A 1 126 ? -7.731  14.855  52.995 1   26.811  ? 115 SER A N    1 
ATOM   1719 C  CA   . SER A 1 126 ? -8.892  14.076  53.295 1   31.609  ? 115 SER A CA   1 
ATOM   1720 C  C    . SER A 1 126 ? -10.056 14.605  52.474 1   30.058  ? 115 SER A C    1 
ATOM   1721 O  O    . SER A 1 126 ? -10.865 13.847  51.91  1   35.584  ? 115 SER A O    1 
ATOM   1722 C  CB   . SER A 1 126 ? -9.154  14.109  54.771 1   35.392  ? 115 SER A CB   1 
ATOM   1723 O  OG   . SER A 1 126 ? -10.36  13.445  55.145 1   35.333  ? 115 SER A OG   1 
ATOM   1724 H  H    . SER A 1 126 ? -7.27   15.235  53.687 1   29.086  ? 115 SER A H    1 
ATOM   1725 H  HA   . SER A 1 126 ? -8.717  13.139  53.025 1   31.002  ? 115 SER A HA   1 
ATOM   1726 H  HB2  . SER A 1 126 ? -8.404  13.691  55.233 1   34.447  ? 115 SER A HB2  1 
ATOM   1727 H  HB3  . SER A 1 126 ? -9.199  15.038  55.064 1   34.424  ? 115 SER A HB3  1 
ATOM   1728 H  HG   . SER A 1 126 ? -10.459 13.497  55.99  0   35.18   ? 115 SER A HG   1 
ATOM   1729 N  N    . ALA A 1 127 ? -10.227 15.914  52.51  1   34.224  ? 116 ALA A N    1 
ATOM   1730 C  CA   . ALA A 1 127 ? -11.345 16.53   51.799 1   33.303  ? 116 ALA A CA   1 
ATOM   1731 C  C    . ALA A 1 127 ? -11.152 16.397  50.291 1   33.74   ? 116 ALA A C    1 
ATOM   1732 O  O    . ALA A 1 127 ? -12.106 16.155  49.55  1   33.023  ? 116 ALA A O    1 
ATOM   1733 C  CB   . ALA A 1 127 ? -11.456 17.99   52.19  1   38.46   ? 116 ALA A CB   1 
ATOM   1734 H  H    . ALA A 1 127 ? -9.652  16.442  52.985 1   32.954  ? 116 ALA A H    1 
ATOM   1735 H  HA   . ALA A 1 127 ? -12.184 16.056  52.054 1   34.437  ? 116 ALA A HA   1 
ATOM   1736 H  HB1  . ALA A 1 127 ? -11.543 18.064  53.155 1   36.838  ? 116 ALA A HB1  1 
ATOM   1737 H  HB2  . ALA A 1 127 ? -10.66  18.467  51.902 1   36.85   ? 116 ALA A HB2  1 
ATOM   1738 H  HB3  . ALA A 1 127 ? -12.237 18.383  51.766 1   36.85   ? 116 ALA A HB3  1 
ATOM   1739 N  N    . GLY A 1 128 ? -9.891  16.493  49.868 1   29.346  ? 117 GLY A N    1 
ATOM   1740 C  CA   . GLY A 1 128 ? -9.537  16.27   48.468 1   30.396  ? 117 GLY A CA   1 
ATOM   1741 C  C    . GLY A 1 128 ? -9.855  14.866  47.95  1   32.727  ? 117 GLY A C    1 
ATOM   1742 O  O    . GLY A 1 128 ? -10.247 14.698  46.795 1   35.631  ? 117 GLY A O    1 
ATOM   1743 H  H    . GLY A 1 128 ? -9.231  16.717  50.458 1   30.628  ? 117 GLY A H    1 
ATOM   1744 H  HA2  . GLY A 1 128 ? -10.017 16.931  47.915 1   30.644  ? 117 GLY A HA2  1 
ATOM   1745 H  HA3  . GLY A 1 128 ? -8.572  16.44   48.359 1   30.644  ? 117 GLY A HA3  1 
ATOM   1746 N  N    . LEU A 1 129 ? -9.69   13.829  48.788 1   32.87   ? 118 LEU A N    1 
ATOM   1747 C  CA   . LEU A 1 129 ? -10.064 12.489  48.364 1   32.62   ? 118 LEU A CA   1 
ATOM   1748 C  C    . LEU A 1 129 ? -11.571 12.449  48.09  1   37.149  ? 118 LEU A C    1 
ATOM   1749 O  O    . LEU A 1 129 ? -12.025 11.815  47.136 1   31.606  ? 118 LEU A O    1 
ATOM   1750 C  CB   . LEU A 1 129 ? -9.672  11.448  49.39  1   30.117  ? 118 LEU A CB   1 
ATOM   1751 C  CG   . LEU A 1 129 ? -8.167  11.338  49.584 1   33.751  ? 118 LEU A CG   1 
ATOM   1752 C  CD1  . LEU A 1 129 ? -7.907  10.678  50.925 1   36.074  ? 118 LEU A CD1  1 
ATOM   1753 C  CD2  . LEU A 1 129 ? -7.497  10.562  48.491 1   36.522  ? 118 LEU A CD2  1 
ATOM   1754 H  H    . LEU A 1 129 ? -9.346  13.958  49.624 1   32.737  ? 118 LEU A H    1 
ATOM   1755 H  HA   . LEU A 1 129 ? -9.591  12.294  47.515 1   33.008  ? 118 LEU A HA   1 
ATOM   1756 H  HB2  . LEU A 1 129 ? -10.087 11.686  50.251 1   31.544  ? 118 LEU A HB2  1 
ATOM   1757 H  HB3  . LEU A 1 129 ? -10.018 10.574  49.097 1   31.574  ? 118 LEU A HB3  1 
ATOM   1758 H  HG   . LEU A 1 129 ? -7.782  12.25   49.602 1   33.958  ? 118 LEU A HG   1 
ATOM   1759 H  HD11 . LEU A 1 129 ? -8.236  11.249  51.639 1   35.312  ? 118 LEU A HD11 1 
ATOM   1760 H  HD12 . LEU A 1 129 ? -6.951  10.538  51.039 1   35.359  ? 118 LEU A HD12 1 
ATOM   1761 H  HD13 . LEU A 1 129 ? -8.365  9.821   50.96  1   35.357  ? 118 LEU A HD13 1 
ATOM   1762 H  HD21 . LEU A 1 129 ? -7.615  11.023  47.644 1   35.642  ? 118 LEU A HD21 1 
ATOM   1763 H  HD22 . LEU A 1 129 ? -7.89   9.675   48.434 1   35.63   ? 118 LEU A HD22 1 
ATOM   1764 H  HD23 . LEU A 1 129 ? -6.547  10.482  48.685 1   35.655  ? 118 LEU A HD23 1 
ATOM   1765 N  N    . ALA A 1 130 ? -12.356 13.061  48.957 1   32.128  ? 119 ALA A N    1 
ATOM   1766 C  CA   . ALA A 1 130 ? -13.798 13.092  48.734 1   36.94   ? 119 ALA A CA   1 
ATOM   1767 C  C    . ALA A 1 130 ? -14.124 13.891  47.469 1   39.634  ? 119 ALA A C    1 
ATOM   1768 O  O    . ALA A 1 130 ? -14.997 13.473  46.725 1   36.694  ? 119 ALA A O    1 
ATOM   1769 C  CB   . ALA A 1 130 ? -14.563 13.634  49.918 1   35.998  ? 119 ALA A CB   1 
ATOM   1770 H  H    . ALA A 1 130 ? -12.007 13.46   49.701 1   34.305  ? 119 ALA A H    1 
ATOM   1771 H  HA   . ALA A 1 130 ? -14.096 12.153  48.578 1   36.222  ? 119 ALA A HA   1 
ATOM   1772 H  HB1  . ALA A 1 130 ? -14.395 13.079  50.698 1   36.275  ? 119 ALA A HB1  1 
ATOM   1773 H  HB2  . ALA A 1 130 ? -14.277 14.544  50.104 1   36.275  ? 119 ALA A HB2  1 
ATOM   1774 H  HB3  . ALA A 1 130 ? -15.515 13.631  49.721 1   36.275  ? 119 ALA A HB3  1 
ATOM   1775 N  N    . CYS A 1 131 ? -13.477 15.045  47.262 1   39.394  ? 120 CYS A N    1 
ATOM   1776 C  CA   . CYS A 1 131 ? -13.698 15.803  46.045 1   40.802  ? 120 CYS A CA   1 
ATOM   1777 C  C    . CYS A 1 131 ? -13.46  14.943  44.802 1   42.894  ? 120 CYS A C    1 
ATOM   1778 O  O    . CYS A 1 131 ? -14.273 14.966  43.897 1   36.67   ? 120 CYS A O    1 
ATOM   1779 C  CB   . CYS A 1 131 ? -12.783 17.008  45.898 1   34.523  ? 120 CYS A CB   1 
ATOM   1780 S  SG   . CYS A 1 131 ? -13.121 18.247  47.188 1   40.859  ? 120 CYS A SG   1 
ATOM   1781 H  H    . CYS A 1 131 ? -12.896 15.366  47.89  1   39.655  ? 120 CYS A H    1 
ATOM   1782 H  HA   . CYS A 1 131 ? -14.638 16.11   46.039 1   39.583  ? 120 CYS A HA   1 
ATOM   1783 H  HB2  . CYS A 1 131 ? -11.845 16.721  45.967 1   37.078  ? 120 CYS A HB2  1 
ATOM   1784 H  HB3  . CYS A 1 131 ? -12.918 17.42   45.015 1   37.11   ? 120 CYS A HB3  1 
ATOM   1785 H  HG   . CYS A 1 131 ? -12.293 19.062  46.85  0   40.71   ? 120 CYS A HG   1 
ATOM   1786 N  N    . ALA A 1 132 ? -12.335 14.217  44.76  1   37.62   ? 121 ALA A N    1 
ATOM   1787 C  CA   . ALA A 1 132 ? -11.977 13.481  43.574 1   35.017  ? 121 ALA A CA   1 
ATOM   1788 C  C    . ALA A 1 132 ? -12.926 12.296  43.404 1   43.117  ? 121 ALA A C    1 
ATOM   1789 O  O    . ALA A 1 132 ? -13.235 11.944  42.265 1   38.371  ? 121 ALA A O    1 
ATOM   1790 C  CB   . ALA A 1 132 ? -10.508 13.081  43.503 1   39.421  ? 121 ALA A CB   1 
ATOM   1791 H  H    . ALA A 1 132 ? -11.781 14.187  45.487 1   38.212  ? 121 ALA A H    1 
ATOM   1792 H  HA   . ALA A 1 132 ? -12.147 14.09   42.802 1   37.745  ? 121 ALA A HA   1 
ATOM   1793 H  HB1  . ALA A 1 132 ? -9.955  13.878  43.446 1   38.08   ? 121 ALA A HB1  1 
ATOM   1794 H  HB2  . ALA A 1 132 ? -10.268 12.58   44.301 1   38.08   ? 121 ALA A HB2  1 
ATOM   1795 H  HB3  . ALA A 1 132 ? -10.357 12.527  42.719 1   38.113  ? 121 ALA A HB3  1 
ATOM   1796 N  N    . ALA A 1 133 ? -13.413 11.694  44.497 1   37.091  ? 122 ALA A N    1 
ATOM   1797 C  CA   . ALA A 1 133 ? -14.28  10.531  44.363 1   36.407  ? 122 ALA A CA   1 
ATOM   1798 C  C    . ALA A 1 133 ? -15.561 10.991  43.669 1   37.361  ? 122 ALA A C    1 
ATOM   1799 O  O    . ALA A 1 133 ? -16.112 10.29   42.859 1   35.47   ? 122 ALA A O    1 
ATOM   1800 C  CB   . ALA A 1 133 ? -14.6   9.889   45.692 1   38.749  ? 122 ALA A CB   1 
ATOM   1801 H  H    . ALA A 1 133 ? -13.201 12.002  45.33  1   38.289  ? 122 ALA A H    1 
ATOM   1802 H  HA   . ALA A 1 133 ? -13.827 9.866   43.777 1   37.164  ? 122 ALA A HA   1 
ATOM   1803 H  HB1  . ALA A 1 133 ? -13.777 9.598   46.121 1   38.038  ? 122 ALA A HB1  1 
ATOM   1804 H  HB2  . ALA A 1 133 ? -15.051 10.531  46.265 1   38.038  ? 122 ALA A HB2  1 
ATOM   1805 H  HB3  . ALA A 1 133 ? -15.178 9.121   45.553 1   38.038  ? 122 ALA A HB3  1 
ATOM   1806 N  N    . VAL A 1 134 ? -16.095 12.107  44.12  1   39.483  ? 123 VAL A N    1 
ATOM   1807 C  CA   . VAL A 1 134 ? -17.333 12.627  43.603 1   38.126  ? 123 VAL A CA   1 
ATOM   1808 C  C    . VAL A 1 134 ? -17.136 12.949  42.121 1   40.482  ? 123 VAL A C    1 
ATOM   1809 O  O    . VAL A 1 134 ? -17.983 12.659  41.32  1   45.107  ? 123 VAL A O    1 
ATOM   1810 C  CB   . VAL A 1 134 ? -17.763 13.857  44.389 1   40.273  ? 123 VAL A CB   1 
ATOM   1811 C  CG1  . VAL A 1 134 ? -18.754 14.687  43.592 1   44.128  ? 123 VAL A CG1  1 
ATOM   1812 C  CG2  . VAL A 1 134 ? -18.33  13.465  45.747 1   39.07   ? 123 VAL A CG2  1 
ATOM   1813 H  H    . VAL A 1 134 ? -15.674 12.564  44.79  1   38.656  ? 123 VAL A H    1 
ATOM   1814 H  HA   . VAL A 1 134 ? -18.021 11.942  43.688 1   39.165  ? 123 VAL A HA   1 
ATOM   1815 H  HB   . VAL A 1 134 ? -16.958 14.406  44.539 1   40.304  ? 123 VAL A HB   1 
ATOM   1816 H  HG11 . VAL A 1 134 ? -19.402 14.101  43.165 1   42.895  ? 123 VAL A HG11 1 
ATOM   1817 H  HG12 . VAL A 1 134 ? -18.282 15.198  42.913 1   42.917  ? 123 VAL A HG12 1 
ATOM   1818 H  HG13 . VAL A 1 134 ? -19.218 15.298  44.189 1   42.89   ? 123 VAL A HG13 1 
ATOM   1819 H  HG21 . VAL A 1 134 ? -18.584 14.265  46.236 1   39.443  ? 123 VAL A HG21 1 
ATOM   1820 H  HG22 . VAL A 1 134 ? -17.656 12.978  46.252 1   39.426  ? 123 VAL A HG22 1 
ATOM   1821 H  HG23 . VAL A 1 134 ? -19.111 12.9    45.623 1   39.426  ? 123 VAL A HG23 1 
ATOM   1822 N  N    . GLU A 1 135 ? -16.004 13.498  41.763 1   42.86   ? 124 GLU A N    1 
ATOM   1823 C  CA   . GLU A 1 135 ? -15.798 13.92   40.404 1   44.078  ? 124 GLU A CA   1 
ATOM   1824 C  C    . GLU A 1 135 ? -15.667 12.712  39.478 1   50.638  ? 124 GLU A C    1 
ATOM   1825 O  O    . GLU A 1 135 ? -16.194 12.74   38.389 1   49.652  ? 124 GLU A O    1 
ATOM   1826 C  CB   . GLU A 1 135 ? -14.558 14.797  40.381 1   43.216  ? 124 GLU A CB   1 
ATOM   1827 C  CG   . GLU A 1 135 ? -14.007 15.016  38.964 1   52.843  ? 124 GLU A CG   1 
ATOM   1828 C  CD   . GLU A 1 135 ? -13.004 16.156  38.846 1   59.481  ? 124 GLU A CD   1 
ATOM   1829 O  OE1  . GLU A 1 135 ? -13.188 17.092  39.631 1   64.524  ? 124 GLU A OE1  1 
ATOM   1830 O  OE2  . GLU A 1 135 ? -12.063 16.134  38.007 1   57.785  ? 124 GLU A OE2  1 
ATOM   1831 H  H    . GLU A 1 135 ? -15.339 13.624  42.377 1   42.503  ? 124 GLU A H    1 
ATOM   1832 H  HA   . GLU A 1 135 ? -16.579 14.46   40.119 1   44.801  ? 124 GLU A HA   1 
ATOM   1833 H  HB2  . GLU A 1 135 ? -14.778 15.661  40.787 1   45.516  ? 124 GLU A HB2  1 
ATOM   1834 H  HB3  . GLU A 1 135 ? -13.86  14.379  40.927 1   45.416  ? 124 GLU A HB3  1 
ATOM   1835 H  HG2  . GLU A 1 135 ? -13.572 14.191  38.66  1   51.879  ? 124 GLU A HG2  1 
ATOM   1836 H  HG3  . GLU A 1 135 ? -14.755 15.197  38.356 1   51.877  ? 124 GLU A HG3  1 
ATOM   1837 N  N    . ALA A 1 136 ? -14.87  11.703  39.851 1   42.906  ? 125 ALA A N    1 
ATOM   1838 C  CA   . ALA A 1 136 ? -14.683 10.548  39.008 1   41.165  ? 125 ALA A CA   1 
ATOM   1839 C  C    . ALA A 1 136 ? -16.04  9.898   38.729 1   43.29   ? 125 ALA A C    1 
ATOM   1840 O  O    . ALA A 1 136 ? -16.279 9.354   37.664 1   44.874  ? 125 ALA A O    1 
ATOM   1841 C  CB   . ALA A 1 136 ? -13.72  9.575   39.654 1   42.584  ? 125 ALA A CB   1 
ATOM   1842 H  H    . ALA A 1 136 ? -14.432 11.744  40.652 1   44.196  ? 125 ALA A H    1 
ATOM   1843 H  HA   . ALA A 1 136 ? -14.301 10.856  38.14  1   42.177  ? 125 ALA A HA   1 
ATOM   1844 H  HB1  . ALA A 1 136 ? -12.865 10.012  39.805 1   42.179  ? 125 ALA A HB1  1 
ATOM   1845 H  HB2  . ALA A 1 136 ? -14.081 9.274   40.505 1   42.212  ? 125 ALA A HB2  1 
ATOM   1846 H  HB3  . ALA A 1 136 ? -13.589 8.808   39.071 1   42.212  ? 125 ALA A HB3  1 
ATOM   1847 N  N    . VAL A 1 137 ? -16.911 9.846   39.721 1   39.681  ? 126 VAL A N    1 
ATOM   1848 C  CA   . VAL A 1 137 ? -18.181 9.181   39.5   1   40.562  ? 126 VAL A CA   1 
ATOM   1849 C  C    . VAL A 1 137 ? -19.063 10.051  38.607 1   41.891  ? 126 VAL A C    1 
ATOM   1850 O  O    . VAL A 1 137 ? -19.719 9.524   37.738 1   43.424  ? 126 VAL A O    1 
ATOM   1851 C  CB   . VAL A 1 137 ? -18.837 8.876   40.842 1   36.775  ? 126 VAL A CB   1 
ATOM   1852 C  CG1  . VAL A 1 137 ? -20.33  8.601   40.734 1   41.684  ? 126 VAL A CG1  1 
ATOM   1853 C  CG2  . VAL A 1 137 ? -18.137 7.719   41.538 1   43.067  ? 126 VAL A CG2  1 
ATOM   1854 H  H    . VAL A 1 137 ? -16.722 10.211  40.537 1   40.739  ? 126 VAL A H    1 
ATOM   1855 H  HA   . VAL A 1 137 ? -18.013 8.335   39.041 1   39.988  ? 126 VAL A HA   1 
ATOM   1856 H  HB   . VAL A 1 137 ? -18.725 9.676   41.408 1   39.497  ? 126 VAL A HB   1 
ATOM   1857 H  HG11 . VAL A 1 137 ? -20.499 8.013   39.979 1   40.187  ? 126 VAL A HG11 1 
ATOM   1858 H  HG12 . VAL A 1 137 ? -20.808 9.438   40.606 1   40.188  ? 126 VAL A HG12 1 
ATOM   1859 H  HG13 . VAL A 1 137 ? -20.642 8.175   41.55  1   40.198  ? 126 VAL A HG13 1 
ATOM   1860 H  HG21 . VAL A 1 137 ? -18.574 7.536   42.386 1   41.074  ? 126 VAL A HG21 1 
ATOM   1861 H  HG22 . VAL A 1 137 ? -17.206 7.951   41.697 1   41.095  ? 126 VAL A HG22 1 
ATOM   1862 H  HG23 . VAL A 1 137 ? -18.18  6.927   40.975 1   41.09   ? 126 VAL A HG23 1 
ATOM   1863 N  N    . LEU A 1 138 ? -19.071 11.376  38.836 1   43.279  ? 127 LEU A N    1 
ATOM   1864 C  CA   . LEU A 1 138 ? -19.9   12.29   38.077 1   44.224  ? 127 LEU A CA   1 
ATOM   1865 C  C    . LEU A 1 138 ? -19.521 12.295  36.599 1   49.48   ? 127 LEU A C    1 
ATOM   1866 O  O    . LEU A 1 138 ? -20.412 12.45   35.799 1   53.78   ? 127 LEU A O    1 
ATOM   1867 C  CB   . LEU A 1 138 ? -19.892 13.725  38.575 1   41.368  ? 127 LEU A CB   1 
ATOM   1868 C  CG   . LEU A 1 138 ? -20.875 14      39.702 1   52.356  ? 127 LEU A CG   1 
ATOM   1869 C  CD1  . LEU A 1 138 ? -20.714 15.467  40.004 1   52.288  ? 127 LEU A CD1  1 
ATOM   1870 C  CD2  . LEU A 1 138 ? -22.324 13.644  39.365 1   53.838  ? 127 LEU A CD2  1 
ATOM   1871 H  H    . LEU A 1 138 ? -18.541 11.715  39.499 1   43.111  ? 127 LEU A H    1 
ATOM   1872 H  HA   . LEU A 1 138 ? -20.826 11.949  38.133 1   44.595  ? 127 LEU A HA   1 
ATOM   1873 H  HB2  . LEU A 1 138 ? -18.983 13.939  38.89  1   44.429  ? 127 LEU A HB2  1 
ATOM   1874 H  HB3  . LEU A 1 138 ? -20.107 14.318  37.818 1   44.462  ? 127 LEU A HB3  1 
ATOM   1875 H  HG   . LEU A 1 138 ? -20.597 13.479  40.499 1   50.355  ? 127 LEU A HG   1 
ATOM   1876 H  HD11 . LEU A 1 138 ? -19.796 15.646  40.27  1   52.145  ? 127 LEU A HD11 1 
ATOM   1877 H  HD12 . LEU A 1 138 ? -21.314 15.717  40.727 1   52.246  ? 127 LEU A HD12 1 
ATOM   1878 H  HD13 . LEU A 1 138 ? -20.929 15.989  39.213 1   52.145  ? 127 LEU A HD13 1 
ATOM   1879 H  HD21 . LEU A 1 138 ? -22.444 12.681  39.412 1   53.265  ? 127 LEU A HD21 1 
ATOM   1880 H  HD22 . LEU A 1 138 ? -22.534 13.953  38.467 1   53.36   ? 127 LEU A HD22 1 
ATOM   1881 H  HD23 . LEU A 1 138 ? -22.92  14.073  40.001 1   53.329  ? 127 LEU A HD23 1 
ATOM   1882 N  N    . LYS A 1 139 ? -18.227 12.16   36.272 1   52.073  ? 128 LYS A N    1 
ATOM   1883 C  CA   . LYS A 1 139 ? -17.751 12.226  34.909 1   52.195  ? 128 LYS A CA   1 
ATOM   1884 C  C    . LYS A 1 139 ? -17.78  10.856  34.244 1   54.133  ? 128 LYS A C    1 
ATOM   1885 O  O    . LYS A 1 139 ? -17.246 10.709  33.163 1   53.307  ? 128 LYS A O    1 
ATOM   1886 C  CB   . LYS A 1 139 ? -16.331 12.789  34.957 1   55.689  ? 128 LYS A CB   1 
ATOM   1887 C  CG   . LYS A 1 139 ? -16.419 14.242  35.345 1   66.199  ? 128 LYS A CG   1 
ATOM   1888 C  CD   . LYS A 1 139 ? -15.277 15.148  34.917 1   75.56   ? 128 LYS A CD   1 
ATOM   1889 C  CE   . LYS A 1 139 ? -13.941 14.548  35.132 1   74.933  ? 128 LYS A CE   1 
ATOM   1890 N  NZ   . LYS A 1 139 ? -12.988 15.661  34.964 1   72.558  ? 128 LYS A NZ   1 
ATOM   1891 H  H    . LYS A 1 139 ? -17.618 12.021  36.939 1   51.431  ? 128 LYS A H    1 
ATOM   1892 H  HA   . LYS A 1 139 ? -18.335 12.842  34.397 1   53.27   ? 128 LYS A HA   1 
ATOM   1893 H  HB2  . LYS A 1 139 ? -15.792 12.303  35.617 1   57.083  ? 128 LYS A HB2  1 
ATOM   1894 H  HB3  . LYS A 1 139 ? -15.903 12.71   34.078 1   57.144  ? 128 LYS A HB3  1 
ATOM   1895 H  HG2  . LYS A 1 139 ? -17.253 14.606  34.975 1   65.32   ? 128 LYS A HG2  1 
ATOM   1896 H  HG3  . LYS A 1 139 ? -16.499 14.288  36.322 1   65.335  ? 128 LYS A HG3  1 
ATOM   1897 H  HD2  . LYS A 1 139 ? -15.382 15.36   33.964 1   73.194  ? 128 LYS A HD2  1 
ATOM   1898 H  HD3  . LYS A 1 139 ? -15.336 15.988  35.42  1   73.23   ? 128 LYS A HD3  1 
ATOM   1899 H  HE2  . LYS A 1 139 ? -13.865 14.176  36.029 1   74.495  ? 128 LYS A HE2  1 
ATOM   1900 H  HE3  . LYS A 1 139 ? -13.759 13.854  34.474 1   74.413  ? 128 LYS A HE3  1 
ATOM   1901 H  HZ1  . LYS A 1 139 ? -13.072 16.247  35.65  1   73.296  ? 128 LYS A HZ1  1 
ATOM   1902 H  HZ2  . LYS A 1 139 ? -13.144 16.092  34.182 1   73.297  ? 128 LYS A HZ2  1 
ATOM   1903 H  HZ3  . LYS A 1 139 ? -12.143 15.336  34.957 1   73.286  ? 128 LYS A HZ3  1 
ATOM   1904 N  N    . GLY A 1 140 ? -18.312 9.837   34.915 1   43.345  ? 129 GLY A N    1 
ATOM   1905 C  CA   . GLY A 1 140 ? -18.459 8.538   34.301 1   45.828  ? 129 GLY A CA   1 
ATOM   1906 C  C    . GLY A 1 140 ? -17.152 7.768   34.219 1   50.384  ? 129 GLY A C    1 
ATOM   1907 O  O    . GLY A 1 140 ? -17.184 6.637   33.725 1   58.895  ? 129 GLY A O    1 
ATOM   1908 H  H    . GLY A 1 140 ? -18.581 9.947   35.781 1   46.36   ? 129 GLY A H    1 
ATOM   1909 H  HA2  . GLY A 1 140 ? -19.111 8.014   34.822 1   46.208  ? 129 GLY A HA2  1 
ATOM   1910 H  HA3  . GLY A 1 140 ? -18.826 8.653   33.393 1   46.269  ? 129 GLY A HA3  1 
ATOM   1911 N  N    . GLU A 1 141 ? -16.048 8.274   34.816 1   49.942  ? 130 GLU A N    1 
ATOM   1912 C  CA   . GLU A 1 141 ? -14.815 7.469   34.837 1   54.107  ? 130 GLU A CA   1 
ATOM   1913 C  C    . GLU A 1 141 ? -14.959 6.192   35.704 1   53.592  ? 130 GLU A C    1 
ATOM   1914 O  O    . GLU A 1 141 ? -14.275 5.2     35.438 1   45.985  ? 130 GLU A O    1 
ATOM   1915 C  CB   . GLU A 1 141 ? -13.541 8.173   35.3   1   58.197  ? 130 GLU A CB   1 
ATOM   1916 C  CG   . GLU A 1 141 ? -13.214 9.469   34.563 1   80.538  ? 130 GLU A CG   1 
ATOM   1917 C  CD   . GLU A 1 141 ? -12.117 10.324  35.209 1   98.115  ? 130 GLU A CD   1 
ATOM   1918 O  OE1  . GLU A 1 141 ? -11.583 9.97    36.295 1   93.822  ? 130 GLU A OE1  1 
ATOM   1919 O  OE2  . GLU A 1 141 ? -11.788 11.372  34.604 1   90.233  ? 130 GLU A OE2  1 
ATOM   1920 H  H    . GLU A 1 141 ? -16.059 9.096   35.214 1   51.074  ? 130 GLU A H    1 
ATOM   1921 H  HA   . GLU A 1 141 ? -14.643 7.174   33.907 1   53.917  ? 130 GLU A HA   1 
ATOM   1922 H  HB2  . GLU A 1 141 ? -13.626 8.371   36.256 1   61.767  ? 130 GLU A HB2  1 
ATOM   1923 H  HB3  . GLU A 1 141 ? -12.787 7.556   35.192 1   61.655  ? 130 GLU A HB3  1 
ATOM   1924 H  HG2  . GLU A 1 141 ? -12.936 9.251   33.648 1   78.117  ? 130 GLU A HG2  1 
ATOM   1925 H  HG3  . GLU A 1 141 ? -14.029 10.011  34.498 1   77.791  ? 130 GLU A HG3  1 
ATOM   1926 N  N    . LEU A 1 142 ? -15.804 6.244   36.767 1   43.638  ? 131 LEU A N    1 
ATOM   1927 C  CA   . LEU A 1 142 ? -16.052 5.147   37.705 1   39.559  ? 131 LEU A CA   1 
ATOM   1928 C  C    . LEU A 1 142 ? -17.554 4.954   37.85  1   34.749  ? 131 LEU A C    1 
ATOM   1929 O  O    . LEU A 1 142 ? -18.325 5.905   37.788 1   42.278  ? 131 LEU A O    1 
ATOM   1930 C  CB   . LEU A 1 142 ? -15.4   5.446   39.063 1   42.722  ? 131 LEU A CB   1 
ATOM   1931 C  CG   . LEU A 1 142 ? -13.873 5.582   39.024 1   44.563  ? 131 LEU A CG   1 
ATOM   1932 C  CD1  . LEU A 1 142 ? -13.279 6.118   40.3   1   50.666  ? 131 LEU A CD1  1 
ATOM   1933 C  CD2  . LEU A 1 142 ? -13.318 4.244   38.724 1   42.055  ? 131 LEU A CD2  1 
ATOM   1934 H  H    . LEU A 1 142 ? -16.249 7.028   36.913 1   44.87   ? 131 LEU A H    1 
ATOM   1935 H  HA   . LEU A 1 142 ? -15.664 4.317   37.33  1   40.028  ? 131 LEU A HA   1 
ATOM   1936 H  HB2  . LEU A 1 142 ? -15.779 6.287   39.41  1   42.387  ? 131 LEU A HB2  1 
ATOM   1937 H  HB3  . LEU A 1 142 ? -15.637 4.723   39.689 1   42.387  ? 131 LEU A HB3  1 
ATOM   1938 H  HG   . LEU A 1 142 ? -13.63  6.196   38.284 1   44.827  ? 131 LEU A HG   1 
ATOM   1939 H  HD11 . LEU A 1 142 ? -13.685 6.973   40.514 1   48.573  ? 131 LEU A HD11 1 
ATOM   1940 H  HD12 . LEU A 1 142 ? -12.32  6.234   40.19  1   48.642  ? 131 LEU A HD12 1 
ATOM   1941 H  HD13 . LEU A 1 142 ? -13.448 5.493   41.021 1   48.515  ? 131 LEU A HD13 1 
ATOM   1942 H  HD21 . LEU A 1 142 ? -13.489 4.021   37.794 1   42.778  ? 131 LEU A HD21 1 
ATOM   1943 H  HD22 . LEU A 1 142 ? -13.736 3.58    39.298 1   42.805  ? 131 LEU A HD22 1 
ATOM   1944 H  HD23 . LEU A 1 142 ? -12.359 4.248   38.882 1   42.87   ? 131 LEU A HD23 1 
ATOM   1945 N  N    . ASP A 1 143 ? -18.016 3.739   38.148 1   40.517  ? 132 ASP A N    1 
ATOM   1946 C  CA   . ASP A 1 143 ? -19.453 3.582   38.437 1   38.772  ? 132 ASP A CA   1 
ATOM   1947 C  C    . ASP A 1 143 ? -19.847 4.061   39.849 1   49.35   ? 132 ASP A C    1 
ATOM   1948 O  O    . ASP A 1 143 ? -20.985 4.559   40.094 1   39.19   ? 132 ASP A O    1 
ATOM   1949 C  CB   . ASP A 1 143 ? -19.868 2.131   38.241 1   46.318  ? 132 ASP A CB   1 
ATOM   1950 C  CG   . ASP A 1 143 ? -19.692 1.603   36.811 1   61.263  ? 132 ASP A CG   1 
ATOM   1951 O  OD1  . ASP A 1 143 ? -20.009 2.378   35.872 1   77.187  ? 132 ASP A OD1  1 
ATOM   1952 O  OD2  . ASP A 1 143 ? -19.228 0.436   36.635 1   61.965  ? 132 ASP A OD2  1 
ATOM   1953 H  H    . ASP A 1 143 ? -17.461 3.013   38.176 1   38.735  ? 132 ASP A H    1 
ATOM   1954 H  HA   . ASP A 1 143 ? -19.958 4.114   37.782 1   42.34   ? 132 ASP A HA   1 
ATOM   1955 H  HB2  . ASP A 1 143 ? -19.339 1.567   38.843 1   47.414  ? 132 ASP A HB2  1 
ATOM   1956 H  HB3  . ASP A 1 143 ? -20.812 2.035   38.488 1   47.424  ? 132 ASP A HB3  1 
ATOM   1957 N  N    . ASN A 1 144 ? -18.914 3.832   40.802 1   43.184  ? 133 ASN A N    1 
ATOM   1958 C  CA   . ASN A 1 144 ? -19.08  4.234   42.193 1   36.47   ? 133 ASN A CA   1 
ATOM   1959 C  C    . ASN A 1 144 ? -17.703 4.338   42.841 1   34.791  ? 133 ASN A C    1 
ATOM   1960 O  O    . ASN A 1 144 ? -16.653 4.067   42.219 1   37.377  ? 133 ASN A O    1 
ATOM   1961 C  CB   . ASN A 1 144 ? -20.105 3.326   42.833 1   33.247  ? 133 ASN A CB   1 
ATOM   1962 C  CG   . ASN A 1 144 ? -19.621 1.899   42.844 1   37.512  ? 133 ASN A CG   1 
ATOM   1963 O  OD1  . ASN A 1 144 ? -18.405 1.605   42.709 1   38.225  ? 133 ASN A OD1  1 
ATOM   1964 N  ND2  . ASN A 1 144 ? -20.578 0.998   42.971 1   35.353  ? 133 ASN A ND2  1 
ATOM   1965 H  H    . ASN A 1 144 ? -18.146 3.395   40.567 1   42.799  ? 133 ASN A H    1 
ATOM   1966 H  HA   . ASN A 1 144 ? -19.467 5.138   42.191 1   36.783  ? 133 ASN A HA   1 
ATOM   1967 H  HB2  . ASN A 1 144 ? -20.269 3.616   43.752 1   34.925  ? 133 ASN A HB2  1 
ATOM   1968 H  HB3  . ASN A 1 144 ? -20.947 3.381   42.34  1   34.998  ? 133 ASN A HB3  1 
ATOM   1969 H  HD21 . ASN A 1 144 ? -20.399 0.143   42.82  1   36.188  ? 133 ASN A HD21 1 
ATOM   1970 H  HD22 . ASN A 1 144 ? -21.396 1.245   43.21  1   36.019  ? 133 ASN A HD22 1 
ATOM   1971 N  N    . ALA A 1 145 ? -17.703 4.824   44.077 1   31.33   ? 134 ALA A N    1 
ATOM   1972 C  CA   . ALA A 1 145 ? -16.427 5.117   44.712 1   31.733  ? 134 ALA A CA   1 
ATOM   1973 C  C    . ALA A 1 145 ? -16.545 5.262   46.227 1   33.025  ? 134 ALA A C    1 
ATOM   1974 O  O    . ALA A 1 145 ? -17.601 5.628   46.767 1   37.381  ? 134 ALA A O    1 
ATOM   1975 C  CB   . ALA A 1 145 ? -15.833 6.326   44.112 1   30.281  ? 134 ALA A CB   1 
ATOM   1976 H  H    . ALA A 1 145 ? -18.484 4.978   44.527 1   32.274  ? 134 ALA A H    1 
ATOM   1977 H  HA   . ALA A 1 145 ? -15.822 4.348   44.531 1   31.667  ? 134 ALA A HA   1 
ATOM   1978 H  HB1  . ALA A 1 145 ? -15.53  6.131   43.209 1   30.771  ? 134 ALA A HB1  1 
ATOM   1979 H  HB2  . ALA A 1 145 ? -16.497 7.035   44.081 1   30.73   ? 134 ALA A HB2  1 
ATOM   1980 H  HB3  . ALA A 1 145 ? -15.076 6.618   44.647 1   30.74   ? 134 ALA A HB3  1 
ATOM   1981 N  N    . TYR A 1 146 ? -15.45  4.861   46.879 1   31.714  ? 135 TYR A N    1 
ATOM   1982 C  CA   . TYR A 1 146 ? -15.285 4.962   48.318 1   33.433  ? 135 TYR A CA   1 
ATOM   1983 C  C    . TYR A 1 146 ? -14.051 5.817   48.562 1   31.011  ? 135 TYR A C    1 
ATOM   1984 O  O    . TYR A 1 146 ? -13.018 5.564   47.948 1   30.854  ? 135 TYR A O    1 
ATOM   1985 C  CB   . TYR A 1 146 ? -15.138 3.525   48.848 1   31.095  ? 135 TYR A CB   1 
ATOM   1986 C  CG   . TYR A 1 146 ? -15.241 3.447   50.348 1   33.728  ? 135 TYR A CG   1 
ATOM   1987 C  CD1  . TYR A 1 146 ? -14.174 3.827   51.174 1   33.918  ? 135 TYR A CD1  1 
ATOM   1988 C  CD2  . TYR A 1 146 ? -16.412 3.04    50.951 1   36.822  ? 135 TYR A CD2  1 
ATOM   1989 C  CE1  . TYR A 1 146 ? -14.281 3.782   52.552 1   40.487  ? 135 TYR A CE1  1 
ATOM   1990 C  CE2  . TYR A 1 146 ? -16.514 2.957   52.32  1   34.865  ? 135 TYR A CE2  1 
ATOM   1991 C  CZ   . TYR A 1 146 ? -15.455 3.34    53.125 1   41.847  ? 135 TYR A CZ   1 
ATOM   1992 O  OH   . TYR A 1 146 ? -15.6   3.276   54.471 1   38.316  ? 135 TYR A OH   1 
ATOM   1993 H  H    . TYR A 1 146 ? -14.762 4.504   46.395 1   32.387  ? 135 TYR A H    1 
ATOM   1994 H  HA   . TYR A 1 146 ? -16.083 5.39    48.72  1   32.275  ? 135 TYR A HA   1 
ATOM   1995 H  HB2  . TYR A 1 146 ? -15.84  2.966   48.447 1   32.249  ? 135 TYR A HB2  1 
ATOM   1996 H  HB3  . TYR A 1 146 ? -14.264 3.172   48.567 1   32.228  ? 135 TYR A HB3  1 
ATOM   1997 H  HD1  . TYR A 1 146 ? -13.369 4.13    50.783 1   35.325  ? 135 TYR A HD1  1 
ATOM   1998 H  HD2  . TYR A 1 146 ? -17.141 2.77    50.415 1   35.614  ? 135 TYR A HD2  1 
ATOM   1999 H  HE1  . TYR A 1 146 ? -13.553 4.031   53.095 1   39.04   ? 135 TYR A HE1  1 
ATOM   2000 H  HE2  . TYR A 1 146 ? -17.321 2.672   52.714 1   36.823  ? 135 TYR A HE2  1 
ATOM   2001 H  HH   . TYR A 1 146 ? -15.9   4.03    54.774 0   38.38   ? 135 TYR A HH   1 
ATOM   2002 N  N    . SER A 1 147 ? -14.181 6.8     49.486 1   31.792  ? 136 SER A N    1 
ATOM   2003 C  CA   . SER A 1 147 ? -13.097 7.633   49.95  1   33.306  ? 136 SER A CA   1 
ATOM   2004 C  C    . SER A 1 147 ? -12.815 7.314   51.424 1   32.314  ? 136 SER A C    1 
ATOM   2005 O  O    . SER A 1 147 ? -13.653 7.616   52.285 1   29.149  ? 136 SER A O    1 
ATOM   2006 C  CB   . SER A 1 147 ? -13.489 9.1     49.836 1   30.225  ? 136 SER A CB   1 
ATOM   2007 O  OG   . SER A 1 147 ? -12.453 10.035  50.164 1   38.784  ? 136 SER A OG   1 
ATOM   2008 H  H    . SER A 1 147 ? -15.011 6.947   49.84  1   31.956  ? 136 SER A H    1 
ATOM   2009 H  HA   . SER A 1 147 ? -12.286 7.46    49.408 1   32.244  ? 136 SER A HA   1 
ATOM   2010 H  HB2  . SER A 1 147 ? -13.784 9.271   48.922 1   32.785  ? 136 SER A HB2  1 
ATOM   2011 H  HB3  . SER A 1 147 ? -14.255 9.265   50.418 1   32.766  ? 136 SER A HB3  1 
ATOM   2012 H  HG   . SER A 1 147 ? -12.741 10.814  50.068 0   38.61   ? 136 SER A HG   1 
ATOM   2013 N  N    . LEU A 1 148 ? -11.585 6.893   51.704 1   33.931  ? 137 LEU A N    1 
ATOM   2014 C  CA   . LEU A 1 148 ? -11.089 6.676   53.059 1   34.903  ? 137 LEU A CA   1 
ATOM   2015 C  C    . LEU A 1 148 ? -10.528 7.962   53.603 1   32.179  ? 137 LEU A C    1 
ATOM   2016 O  O    . LEU A 1 148 ? -9.3    8.181   53.673 1   34.186  ? 137 LEU A O    1 
ATOM   2017 C  CB   . LEU A 1 148 ? -9.983  5.629   52.999 1   36.843  ? 137 LEU A CB   1 
ATOM   2018 C  CG   . LEU A 1 148 ? -9.615  4.99    54.339 1   41.963  ? 137 LEU A CG   1 
ATOM   2019 C  CD1  . LEU A 1 148 ? -10.74  4.204   54.974 1   49.506  ? 137 LEU A CD1  1 
ATOM   2020 C  CD2  . LEU A 1 148 ? -8.502  4.008   54.103 1   41.12   ? 137 LEU A CD2  1 
ATOM   2021 H  H    . LEU A 1 148 ? -11.015 6.73    51.008 1   33.783  ? 137 LEU A H    1 
ATOM   2022 H  HA   . LEU A 1 148 ? -11.83  6.358   53.633 1   34.628  ? 137 LEU A HA   1 
ATOM   2023 H  HB2  . LEU A 1 148 ? -10.269 4.915   52.384 1   37.43   ? 137 LEU A HB2  1 
ATOM   2024 H  HB3  . LEU A 1 148 ? -9.177  6.045   52.616 1   37.444  ? 137 LEU A HB3  1 
ATOM   2025 H  HG   . LEU A 1 148 ? -9.307  5.695   54.965 1   42.041  ? 137 LEU A HG   1 
ATOM   2026 H  HD11 . LEU A 1 148 ? -11.454 4.809   55.237 1   46.941  ? 137 LEU A HD11 1 
ATOM   2027 H  HD12 . LEU A 1 148 ? -10.409 3.737   55.76  1   47.014  ? 137 LEU A HD12 1 
ATOM   2028 H  HD13 . LEU A 1 148 ? -11.085 3.556   54.336 1   47.075  ? 137 LEU A HD13 1 
ATOM   2029 H  HD21 . LEU A 1 148 ? -7.752  4.462   53.683 1   41.363  ? 137 LEU A HD21 1 
ATOM   2030 H  HD22 . LEU A 1 148 ? -8.815  3.296   53.521 1   41.393  ? 137 LEU A HD22 1 
ATOM   2031 H  HD23 . LEU A 1 148 ? -8.216  3.63    54.951 1   41.446  ? 137 LEU A HD23 1 
ATOM   2032 N  N    . SER A 1 149 ? -11.463 8.843   53.855 1   35.731  ? 138 SER A N    1 
ATOM   2033 C  CA   . SER A 1 149 ? -11.196 10.203  54.274 1   36.707  ? 138 SER A CA   1 
ATOM   2034 C  C    . SER A 1 149 ? -11.009 10.241  55.797 1   41.056  ? 138 SER A C    1 
ATOM   2035 O  O    . SER A 1 149 ? -11.95  10.084  56.531 1   46.463  ? 138 SER A O    1 
ATOM   2036 C  CB   . SER A 1 149 ? -12.334 11.108  53.851 1   35.295  ? 138 SER A CB   1 
ATOM   2037 O  OG   . SER A 1 149 ? -12.323 11.477  52.451 1   39.773  ? 138 SER A OG   1 
ATOM   2038 H  H    . SER A 1 149 ? -12.336 8.583   53.776 1   35.06   ? 138 SER A H    1 
ATOM   2039 H  HA   . SER A 1 149 ? -10.362 10.513  53.839 1   36.917  ? 138 SER A HA   1 
ATOM   2040 H  HB2  . SER A 1 149 ? -13.179 10.662  54.051 1   36.629  ? 138 SER A HB2  1 
ATOM   2041 H  HB3  . SER A 1 149 ? -12.305 11.921  54.39  1   36.652  ? 138 SER A HB3  1 
ATOM   2042 H  HG   . SER A 1 149 ? -13     11.981  52.315 0   40.04   ? 138 SER A HG   1 
ATOM   2043 N  N    . ARG A 1 150 ? -9.791  10.544  56.257 1   33.927  ? 139 ARG A N    1 
ATOM   2044 C  CA   . ARG A 1 150 ? -9.519  10.797  57.661 1   31.5    ? 139 ARG A CA   1 
ATOM   2045 C  C    . ARG A 1 150 ? -8.64   12.011  57.713 1   29.388  ? 139 ARG A C    1 
ATOM   2046 O  O    . ARG A 1 150 ? -7.617  12.075  57.039 1   31.518  ? 139 ARG A O    1 
ATOM   2047 C  CB   . ARG A 1 150 ? -8.764  9.606   58.243 1   33.607  ? 139 ARG A CB   1 
ATOM   2048 C  CG   . ARG A 1 150 ? -7.982  9.893   59.497 1   35.318  ? 139 ARG A CG   1 
ATOM   2049 C  CD   . ARG A 1 150 ? -7.478  8.661   60.165 1   32.427  ? 139 ARG A CD   1 
ATOM   2050 N  NE   . ARG A 1 150 ? -7.146  8.974   61.549 1   32.946  ? 139 ARG A NE   1 
ATOM   2051 C  CZ   . ARG A 1 150 ? -6.025  9.488   61.989 1   33.299  ? 139 ARG A CZ   1 
ATOM   2052 N  NH1  . ARG A 1 150 ? -4.999  9.781   61.203 1   28.679  ? 139 ARG A NH1  1 
ATOM   2053 N  NH2  . ARG A 1 150 ? -5.911  9.687   63.277 1   34.293  ? 139 ARG A NH2  1 
ATOM   2054 H  H    . ARG A 1 150 ? -9.095  10.589  55.665 1   34.904  ? 139 ARG A H    1 
ATOM   2055 H  HA   . ARG A 1 150 ? -10.366 10.955  58.141 1   32.011  ? 139 ARG A HA   1 
ATOM   2056 H  HB2  . ARG A 1 150 ? -9.411  8.894   58.435 1   33.496  ? 139 ARG A HB2  1 
ATOM   2057 H  HB3  . ARG A 1 150 ? -8.146  9.267   57.561 1   33.5    ? 139 ARG A HB3  1 
ATOM   2058 H  HG2  . ARG A 1 150 ? -7.217  10.467  59.277 1   34.159  ? 139 ARG A HG2  1 
ATOM   2059 H  HG3  . ARG A 1 150 ? -8.553  10.383  60.127 1   34.161  ? 139 ARG A HG3  1 
ATOM   2060 H  HD2  . ARG A 1 150 ? -8.163  7.962   60.143 1   33.321  ? 139 ARG A HD2  1 
ATOM   2061 H  HD3  . ARG A 1 150 ? -6.682  8.329   59.702 1   33.191  ? 139 ARG A HD3  1 
ATOM   2062 H  HE   . ARG A 1 150 ? -7.752  8.791   62.146 1   33.056  ? 139 ARG A HE   1 
ATOM   2063 H  HH11 . ARG A 1 150 ? -5.139  10.181  60.427 1   30.112  ? 139 ARG A HH11 1 
ATOM   2064 H  HH12 . ARG A 1 150 ? -4.179  9.575   61.458 1   30.092  ? 139 ARG A HH12 1 
ATOM   2065 H  HH21 . ARG A 1 150 ? -6.639  9.818   63.774 1   33.956  ? 139 ARG A HH21 1 
ATOM   2066 H  HH22 . ARG A 1 150 ? -5.102  9.691   63.649 1   33.905  ? 139 ARG A HH22 1 
ATOM   2067 N  N    . PRO A 1 151 ? -8.905  13.016  58.556 1   30.737  ? 140 PRO A N    1 
ATOM   2068 C  CA   . PRO A 1 151 ? -9.963  13.024  59.552 1   28.611  ? 140 PRO A CA   1 
ATOM   2069 C  C    . PRO A 1 151 ? -11.343 13.154  58.922 1   32.543  ? 140 PRO A C    1 
ATOM   2070 O  O    . PRO A 1 151 ? -11.437 13.539  57.748 1   31.059  ? 140 PRO A O    1 
ATOM   2071 C  CB   . PRO A 1 151 ? -9.601  14.236  60.415 1   31.352  ? 140 PRO A CB   1 
ATOM   2072 C  CG   . PRO A 1 151 ? -8.844  15.123  59.515 1   32.032  ? 140 PRO A CG   1 
ATOM   2073 C  CD   . PRO A 1 151 ? -8.061  14.205  58.591 1   30.244  ? 140 PRO A CD   1 
ATOM   2074 H  HA   . PRO A 1 151 ? -9.908  12.2    60.094 1   30.253  ? 140 PRO A HA   1 
ATOM   2075 H  HB2  . PRO A 1 151 ? -10.413 14.686  60.748 1   30.892  ? 140 PRO A HB2  1 
ATOM   2076 H  HB3  . PRO A 1 151 ? -9.05   13.966  61.186 1   30.88   ? 140 PRO A HB3  1 
ATOM   2077 H  HG2  . PRO A 1 151 ? -9.452  15.692  58.998 1   31.458  ? 140 PRO A HG2  1 
ATOM   2078 H  HG3  . PRO A 1 151 ? -8.237  15.697  60.026 1   31.464  ? 140 PRO A HG3  1 
ATOM   2079 H  HD2  . PRO A 1 151 ? -7.961  14.6    57.697 1   30.745  ? 140 PRO A HD2  1 
ATOM   2080 H  HD3  . PRO A 1 151 ? -7.173  14.002  58.961 1   30.747  ? 140 PRO A HD3  1 
ATOM   2081 N  N    . PRO A 1 152 ? -12.402 12.733  59.665 1   31.555  ? 141 PRO A N    1 
ATOM   2082 C  CA   . PRO A 1 152 ? -13.809 12.825  59.208 1   33.665  ? 141 PRO A CA   1 
ATOM   2083 C  C    . PRO A 1 152 ? -14.381 14.253  59.114 1   38.202  ? 141 PRO A C    1 
ATOM   2084 O  O    . PRO A 1 152 ? -13.695 15.19   59.476 1   33.757  ? 141 PRO A O    1 
ATOM   2085 C  CB   . PRO A 1 152 ? -14.531 11.975  60.293 1   35.978  ? 141 PRO A CB   1 
ATOM   2086 C  CG   . PRO A 1 152 ? -13.742 12.189  61.535 1   32.372  ? 141 PRO A CG   1 
ATOM   2087 C  CD   . PRO A 1 152 ? -12.269 12.28   61.067 1   31.448  ? 141 PRO A CD   1 
ATOM   2088 H  HA   . PRO A 1 152 ? -13.89  12.376  58.33  1   34.428  ? 141 PRO A HA   1 
ATOM   2089 H  HB2  . PRO A 1 152 ? -15.462 12.277  60.413 1   34.622  ? 141 PRO A HB2  1 
ATOM   2090 H  HB3  . PRO A 1 152 ? -14.538 11.021  60.043 1   34.607  ? 141 PRO A HB3  1 
ATOM   2091 H  HG2  . PRO A 1 152 ? -14.014 13.017  61.982 1   32.979  ? 141 PRO A HG2  1 
ATOM   2092 H  HG3  . PRO A 1 152 ? -13.863 11.441  62.156 1   32.968  ? 141 PRO A HG3  1 
ATOM   2093 H  HD2  . PRO A 1 152 ? -11.768 12.93   61.607 1   31.649  ? 141 PRO A HD2  1 
ATOM   2094 H  HD3  . PRO A 1 152 ? -11.827 11.403  61.118 1   31.659  ? 141 PRO A HD3  1 
ATOM   2095 N  N    . GLY A 1 153 ? -15.625 14.435  58.634 1   34.899  ? 142 GLY A N    1 
ATOM   2096 C  CA   . GLY A 1 153 ? -16.153 15.755  58.27  1   34.109  ? 142 GLY A CA   1 
ATOM   2097 C  C    . GLY A 1 153 ? -17.552 16.078  58.81  1   33.753  ? 142 GLY A C    1 
ATOM   2098 O  O    . GLY A 1 153 ? -17.868 17.233  59.04  1   38.735  ? 142 GLY A O    1 
ATOM   2099 H  H    . GLY A 1 153 ? -16.158 13.702  58.513 1   35.511  ? 142 GLY A H    1 
ATOM   2100 H  HA2  . GLY A 1 153 ? -15.527 16.441  58.594 1   34.23   ? 142 GLY A HA2  1 
ATOM   2101 H  HA3  . GLY A 1 153 ? -16.173 15.817  57.288 1   34.235  ? 142 GLY A HA3  1 
ATOM   2102 N  N    . HIS A 1 154 ? -18.367 15.069  59.119 1   32.669  ? 143 HIS A N    1 
ATOM   2103 C  CA   . HIS A 1 154 ? -19.81  15.291  59.206 1   36.727  ? 143 HIS A CA   1 
ATOM   2104 C  C    . HIS A 1 154 ? -20.226 16.11   60.419 1   36.561  ? 143 HIS A C    1 
ATOM   2105 O  O    . HIS A 1 154 ? -21.345 16.606  60.419 1   36.35   ? 143 HIS A O    1 
ATOM   2106 C  CB   . HIS A 1 154 ? -20.616 13.982  59.043 1   33.467  ? 143 HIS A CB   1 
ATOM   2107 C  CG   . HIS A 1 154 ? -20.617 13.067  60.183 1   38.816  ? 143 HIS A CG   1 
ATOM   2108 N  ND1  . HIS A 1 154 ? -21.76  12.404  60.591 1   41.149  ? 143 HIS A ND1  1 
ATOM   2109 C  CD2  . HIS A 1 154 ? -19.578 12.678  61.019 1   39.648  ? 143 HIS A CD2  1 
ATOM   2110 C  CE1  . HIS A 1 154 ? -21.428 11.677  61.66  1   46.644  ? 143 HIS A CE1  1 
ATOM   2111 N  NE2  . HIS A 1 154 ? -20.097 11.811  61.91  1   43.063  ? 143 HIS A NE2  1 
ATOM   2112 H  H    . HIS A 1 154 ? -18.032 14.234  59.277 1   33.901  ? 143 HIS A H    1 
ATOM   2113 H  HA   . HIS A 1 154 ? -20.033 15.829  58.41  1   35.293  ? 143 HIS A HA   1 
ATOM   2114 H  HB2  . HIS A 1 154 ? -21.545 14.218  58.833 1   35.44   ? 143 HIS A HB2  1 
ATOM   2115 H  HB3  . HIS A 1 154 ? -20.267 13.502  58.261 1   35.461  ? 143 HIS A HB3  1 
ATOM   2116 H  HD1  . HIS A 1 154 ? -22.551 12.456  60.191 0   41.34   ? 143 HIS A HD1  1 
ATOM   2117 H  HD2  . HIS A 1 154 ? -18.684 12.955  60.982 1   40.195  ? 143 HIS A HD2  1 
ATOM   2118 H  HE1  . HIS A 1 154 ? -22.021 11.118  62.132 1   44.197  ? 143 HIS A HE1  1 
ATOM   2119 H  HE2  . HIS A 1 154 ? -19.698 11.367  62.558 0   42.67   ? 143 HIS A HE2  1 
ATOM   2120 N  N    . HIS A 1 155 ? -19.351 16.279  61.436 1   30.923  ? 144 HIS A N    1 
ATOM   2121 C  CA   . HIS A 1 155 ? -19.739 17.095  62.577 1   36.831  ? 144 HIS A CA   1 
ATOM   2122 C  C    . HIS A 1 155 ? -19.24  18.532  62.398 1   33.364  ? 144 HIS A C    1 
ATOM   2123 O  O    . HIS A 1 155 ? -19.558 19.387  63.23  1   37.46   ? 144 HIS A O    1 
ATOM   2124 C  CB   . HIS A 1 155 ? -19.249 16.596  63.949 1   30.03   ? 144 HIS A CB   1 
ATOM   2125 C  CG   . HIS A 1 155 ? -19.815 15.278  64.298 1   34.789  ? 144 HIS A CG   1 
ATOM   2126 N  ND1  . HIS A 1 155 ? -21.162 14.987  64.439 1   33.32   ? 144 HIS A ND1  1 
ATOM   2127 C  CD2  . HIS A 1 155 ? -19.137 14.133  64.561 1   32.388  ? 144 HIS A CD2  1 
ATOM   2128 C  CE1  . HIS A 1 155 ? -21.28  13.694  64.783 1   36.459  ? 144 HIS A CE1  1 
ATOM   2129 N  NE2  . HIS A 1 155 ? -20.07  13.155  64.855 1   37.422  ? 144 HIS A NE2  1 
ATOM   2130 H  H    . HIS A 1 155 ? -18.53  15.877  61.425 1   33.487  ? 144 HIS A H    1 
ATOM   2131 H  HA   . HIS A 1 155 ? -20.724 17.119  62.605 1   33.733  ? 144 HIS A HA   1 
ATOM   2132 H  HB2  . HIS A 1 155 ? -18.271 16.53   63.931 1   32.539  ? 144 HIS A HB2  1 
ATOM   2133 H  HB3  . HIS A 1 155 ? -19.506 17.248  64.637 1   32.566  ? 144 HIS A HB3  1 
ATOM   2134 H  HD1  . HIS A 1 155 ? -21.832 15.566  64.316 0   33.04   ? 144 HIS A HD1  1 
ATOM   2135 H  HD2  . HIS A 1 155 ? -18.207 14.024  64.544 1   34.212  ? 144 HIS A HD2  1 
ATOM   2136 H  HE1  . HIS A 1 155 ? -22.092 13.244  64.931 1   35.808  ? 144 HIS A HE1  1 
ATOM   2137 H  HE2  . HIS A 1 155 ? -19.905 12.334  65.077 0   37.41   ? 144 HIS A HE2  1 
ATOM   2138 N  N    . CYS A 1 156 ? -18.365 18.756  61.406 1   36.57   ? 145 CYS A N    1 
ATOM   2139 C  CA   . CYS A 1 156 ? -17.705 20.052  61.333 1   39.872  ? 145 CYS A CA   1 
ATOM   2140 C  C    . CYS A 1 156 ? -18.692 21.171  60.937 1   40.419  ? 145 CYS A C    1 
ATOM   2141 O  O    . CYS A 1 156 ? -19.416 21.089  59.939 1   38.122  ? 145 CYS A O    1 
ATOM   2142 C  CB   . CYS A 1 156 ? -16.626 20.041  60.286 1   32.23   ? 145 CYS A CB   1 
ATOM   2143 S  SG   . CYS A 1 156 ? -15.487 21.435  60.529 1   40.761  ? 145 CYS A SG   1 
ATOM   2144 H  H    . CYS A 1 156 ? -18.181 18.117  60.779 1   36.354  ? 145 CYS A H    1 
ATOM   2145 H  HA   . CYS A 1 156 ? -17.317 20.26   62.222 1   37.838  ? 145 CYS A HA   1 
ATOM   2146 H  HB2  . CYS A 1 156 ? -16.12  19.201  60.342 1   35.446  ? 145 CYS A HB2  1 
ATOM   2147 H  HB3  . CYS A 1 156 ? -17.028 20.105  59.392 1   35.489  ? 145 CYS A HB3  1 
ATOM   2148 H  HG   . CYS A 1 156 ? -14.747 21.198  59.606 0   40.6    ? 145 CYS A HG   1 
ATOM   2149 N  N    . LEU A 1 157 ? -18.711 22.259  61.694 1   44.499  ? 146 LEU A N    1 
ATOM   2150 C  CA   . LEU A 1 157 ? -19.466 23.436  61.282 1   37.51   ? 146 LEU A CA   1 
ATOM   2151 C  C    . LEU A 1 157 ? -18.573 24.4    60.506 1   36.78   ? 146 LEU A C    1 
ATOM   2152 O  O    . LEU A 1 157 ? -17.351 24.259  60.551 1   39.464  ? 146 LEU A O    1 
ATOM   2153 C  CB   . LEU A 1 157 ? -20.092 24.094  62.496 1   38.958  ? 146 LEU A CB   1 
ATOM   2154 C  CG   . LEU A 1 157 ? -21.161 23.264  63.211 1   40.218  ? 146 LEU A CG   1 
ATOM   2155 C  CD1  . LEU A 1 157 ? -21.543 23.804  64.606 1   47.048  ? 146 LEU A CD1  1 
ATOM   2156 C  CD2  . LEU A 1 157 ? -22.359 23.233  62.393 1   39.564  ? 146 LEU A CD2  1 
ATOM   2157 H  H    . LEU A 1 157 ? -18.249 22.278  62.483 1   41.786  ? 146 LEU A H    1 
ATOM   2158 H  HA   . LEU A 1 157 ? -20.188 23.137  60.677 1   38.992  ? 146 LEU A HA   1 
ATOM   2159 H  HB2  . LEU A 1 157 ? -19.375 24.297  63.139 1   38.945  ? 146 LEU A HB2  1 
ATOM   2160 H  HB3  . LEU A 1 157 ? -20.493 24.948  62.215 1   38.973  ? 146 LEU A HB3  1 
ATOM   2161 H  HG   . LEU A 1 157 ? -20.825 22.337  63.313 1   41.023  ? 146 LEU A HG   1 
ATOM   2162 H  HD11 . LEU A 1 157 ? -20.749 23.85   65.164 1   44.937  ? 146 LEU A HD11 1 
ATOM   2163 H  HD12 . LEU A 1 157 ? -22.193 23.21   65.017 1   44.909  ? 146 LEU A HD12 1 
ATOM   2164 H  HD13 . LEU A 1 157 ? -21.927 24.692  64.517 1   44.937  ? 146 LEU A HD13 1 
ATOM   2165 H  HD21 . LEU A 1 157 ? -22.168 22.789  61.551 1   39.731  ? 146 LEU A HD21 1 
ATOM   2166 H  HD22 . LEU A 1 157 ? -22.659 24.141  62.219 1   39.76   ? 146 LEU A HD22 1 
ATOM   2167 H  HD23 . LEU A 1 157 ? -23.059 22.746  62.861 1   39.823  ? 146 LEU A HD23 1 
ATOM   2168 N  N    . PRO A 1 158 ? -19.139 25.399  59.772 1   37.965  ? 147 PRO A N    1 
ATOM   2169 C  CA   . PRO A 1 158 ? -18.358 26.278  58.917 1   38.867  ? 147 PRO A CA   1 
ATOM   2170 C  C    . PRO A 1 158 ? -17.23  26.924  59.685 1   39.168  ? 147 PRO A C    1 
ATOM   2171 O  O    . PRO A 1 158 ? -16.14  27.024  59.153 1   36.58   ? 147 PRO A O    1 
ATOM   2172 C  CB   . PRO A 1 158 ? -19.412 27.282  58.401 1   47.849  ? 147 PRO A CB   1 
ATOM   2173 C  CG   . PRO A 1 158 ? -20.599 26.377  58.23  1   49.019  ? 147 PRO A CG   1 
ATOM   2174 C  CD   . PRO A 1 158 ? -20.586 25.572  59.534 1   46.24   ? 147 PRO A CD   1 
ATOM   2175 H  HA   . PRO A 1 158 ? -17.996 25.756  58.159 1   40.198  ? 147 PRO A HA   1 
ATOM   2176 H  HB2  . PRO A 1 158 ? -19.591 27.988  59.065 1   45.942  ? 147 PRO A HB2  1 
ATOM   2177 H  HB3  . PRO A 1 158 ? -19.138 27.683  57.545 1   45.882  ? 147 PRO A HB3  1 
ATOM   2178 H  HG2  . PRO A 1 158 ? -21.428 26.891  58.138 1   48.122  ? 147 PRO A HG2  1 
ATOM   2179 H  HG3  . PRO A 1 158 ? -20.492 25.793  57.451 1   48.122  ? 147 PRO A HG3  1 
ATOM   2180 H  HD2  . PRO A 1 158 ? -21.012 26.072  60.265 1   44.686  ? 147 PRO A HD2  1 
ATOM   2181 H  HD3  . PRO A 1 158 ? -21.039 24.707  59.42  1   44.654  ? 147 PRO A HD3  1 
ATOM   2182 N  N    . ASP A 1 159 ? -17.491 27.256  60.942 1   38.005  ? 148 ASP A N    1 
ATOM   2183 C  CA   . ASP A 1 159 ? -16.572 28.038  61.757 1   50.658  ? 148 ASP A CA   1 
ATOM   2184 C  C    . ASP A 1 159 ? -16.251 27.336  63.09  1   42.133  ? 148 ASP A C    1 
ATOM   2185 O  O    . ASP A 1 159 ? -15.738 27.986  64.009 1   43.451  ? 148 ASP A O    1 
ATOM   2186 C  CB   . ASP A 1 159 ? -17.145 29.424  62.072 1   48.894  ? 148 ASP A CB   1 
ATOM   2187 C  CG   . ASP A 1 159 ? -18.389 29.349  62.934 1   51.178  ? 148 ASP A CG   1 
ATOM   2188 O  OD1  . ASP A 1 159 ? -18.995 28.239  62.973 1   59.916  ? 148 ASP A OD1  1 
ATOM   2189 O  OD2  . ASP A 1 159 ? -18.694 30.334  63.633 1   62.234  ? 148 ASP A OD2  1 
ATOM   2190 H  H    . ASP A 1 159 ? -18.285 27      61.313 1   40.851  ? 148 ASP A H    1 
ATOM   2191 H  HA   . ASP A 1 159 ? -15.735 28.159  61.257 1   45.781  ? 148 ASP A HA   1 
ATOM   2192 H  HB2  . ASP A 1 159 ? -16.471 29.964  62.534 1   49.767  ? 148 ASP A HB2  1 
ATOM   2193 H  HB3  . ASP A 1 159 ? -17.375 29.874  61.232 1   49.8    ? 148 ASP A HB3  1 
ATOM   2194 N  N    . GLN A 1 160 ? -16.501 26.021  63.192 1   41.314  ? 149 GLN A N    1 
ATOM   2195 C  CA   . GLN A 1 160 ? -16.198 25.322  64.415 1   37.459  ? 149 GLN A CA   1 
ATOM   2196 C  C    . GLN A 1 160 ? -15.995 23.814  64.195 1   38.066  ? 149 GLN A C    1 
ATOM   2197 O  O    . GLN A 1 160 ? -16.875 23.085  63.779 1   33.772  ? 149 GLN A O    1 
ATOM   2198 C  CB   . GLN A 1 160 ? -17.381 25.553  65.332 1   42.583  ? 149 GLN A CB   1 
ATOM   2199 C  CG   . GLN A 1 160 ? -17.136 25.076  66.757 1   55.673  ? 149 GLN A CG   1 
ATOM   2200 C  CD   . GLN A 1 160 ? -18.418 25.111  67.574 1   77.075  ? 149 GLN A CD   1 
ATOM   2201 O  OE1  . GLN A 1 160 ? -19.424 25.75   67.215 1   70.278  ? 149 GLN A OE1  1 
ATOM   2202 N  NE2  . GLN A 1 160 ? -18.389 24.408  68.695 1   77.784  ? 149 GLN A NE2  1 
ATOM   2203 H  H    . GLN A 1 160 ? -16.856 25.559  62.488 1   40.597  ? 149 GLN A H    1 
ATOM   2204 H  HA   . GLN A 1 160 ? -15.38  25.711  64.815 1   39.204  ? 149 GLN A HA   1 
ATOM   2205 H  HB2  . GLN A 1 160 ? -17.589 26.51   65.349 1   43.96   ? 149 GLN A HB2  1 
ATOM   2206 H  HB3  . GLN A 1 160 ? -18.161 25.084  64.967 1   44.072  ? 149 GLN A HB3  1 
ATOM   2207 H  HG2  . GLN A 1 160 ? -16.788 24.159  66.744 1   56.451  ? 149 GLN A HG2  1 
ATOM   2208 H  HG3  . GLN A 1 160 ? -16.464 25.649  67.184 1   56.442  ? 149 GLN A HG3  1 
ATOM   2209 H  HE21 . GLN A 1 160 ? -19.133 24.3    69.167 1   77.417  ? 149 GLN A HE21 1 
ATOM   2210 H  HE22 . GLN A 1 160 ? -17.629 24.045  68.974 1   77.165  ? 149 GLN A HE22 1 
ATOM   2211 N  N    . SER A 1 161 ? -14.838 23.344  64.626 1   35.62   ? 150 SER A N    1 
ATOM   2212 C  CA   . SER A 1 161 ? -14.477 21.959  64.711 1   39.012  ? 150 SER A CA   1 
ATOM   2213 C  C    . SER A 1 161 ? -15.269 21.254  65.798 1   37.144  ? 150 SER A C    1 
ATOM   2214 O  O    . SER A 1 161 ? -15.45  21.791  66.864 1   36.926  ? 150 SER A O    1 
ATOM   2215 C  CB   . SER A 1 161 ? -13.001 21.868  64.999 1   39.079  ? 150 SER A CB   1 
ATOM   2216 O  OG   . SER A 1 161 ? -12.727 20.478  65.12  1   41.351  ? 150 SER A OG   1 
ATOM   2217 H  H    . SER A 1 161 ? -14.212 23.956  64.89  1   37.012  ? 150 SER A H    1 
ATOM   2218 H  HA   . SER A 1 161 ? -14.666 21.526  63.84  1   37.902  ? 150 SER A HA   1 
ATOM   2219 H  HB2  . SER A 1 161 ? -12.487 22.253  64.265 1   39.578  ? 150 SER A HB2  1 
ATOM   2220 H  HB3  . SER A 1 161 ? -12.788 22.331  65.832 1   39.574  ? 150 SER A HB3  1 
ATOM   2221 H  HG   . SER A 1 161 ? -11.917 20.371  65.292 0   41.24   ? 150 SER A HG   1 
ATOM   2222 N  N    . MET A 1 162 ? -15.671 20      65.544 1   31.852  ? 151 MET A N    1 
ATOM   2223 C  CA   . MET A 1 162 ? -16.424 19.239  66.508 1   32.276  ? 151 MET A CA   1 
ATOM   2224 C  C    . MET A 1 162 ? -16.327 17.763  66.123 1   28.746  ? 151 MET A C    1 
ATOM   2225 O  O    . MET A 1 162 ? -16.126 17.374  64.949 1   31.355  ? 151 MET A O    1 
ATOM   2226 C  CB   . MET A 1 162 ? -17.869 19.776  66.485 1   36.503  ? 151 MET A CB   1 
ATOM   2227 C  CG   . MET A 1 162 ? -18.751 19.353  67.592 1   49.55   ? 151 MET A CG   1 
ATOM   2228 S  SD   . MET A 1 162 ? -20.511 19.708  67.289 1   62.33   ? 151 MET A SD   1 
ATOM   2229 C  CE   . MET A 1 162 ? -20.239 21.422  66.938 1   39.183  ? 151 MET A CE   1 
ATOM   2230 H  H    . MET A 1 162 ? -15.465 19.616  64.741 1   33.179  ? 151 MET A H    1 
ATOM   2231 H  HA   . MET A 1 162 ? -16.026 19.372  67.405 1   32.225  ? 151 MET A HA   1 
ATOM   2232 H  HB2  . MET A 1 162 ? -17.825 20.755  66.482 1   38.212  ? 151 MET A HB2  1 
ATOM   2233 H  HB3  . MET A 1 162 ? -18.281 19.501  65.639 1   38.192  ? 151 MET A HB3  1 
ATOM   2234 H  HG2  . MET A 1 162 ? -18.648 18.392  67.735 1   47.449  ? 151 MET A HG2  1 
ATOM   2235 H  HG3  . MET A 1 162 ? -18.477 19.808  68.413 1   47.849  ? 151 MET A HG3  1 
ATOM   2236 H  HE1  . MET A 1 162 ? -21.071 21.914  67.066 1   44.108  ? 151 MET A HE1  1 
ATOM   2237 H  HE2  . MET A 1 162 ? -19.561 21.775  67.543 1   44.059  ? 151 MET A HE2  1 
ATOM   2238 H  HE3  . MET A 1 162 ? -19.944 21.523  66.015 1   44.035  ? 151 MET A HE3  1 
ATOM   2239 N  N    . GLY A 1 163 ? -16.496 16.932  67.134 1   27.394  ? 152 GLY A N    1 
ATOM   2240 C  CA   . GLY A 1 163 ? -16.542 15.49   66.97  1   34.41   ? 152 GLY A CA   1 
ATOM   2241 C  C    . GLY A 1 163 ? -15.376 14.941  66.159 1   35.761  ? 152 GLY A C    1 
ATOM   2242 O  O    . GLY A 1 163 ? -15.614 14.146  65.298 1   33.627  ? 152 GLY A O    1 
ATOM   2243 H  H    . GLY A 1 163 ? -16.614 17.275  67.972 1   30.132  ? 152 GLY A H    1 
ATOM   2244 H  HA2  . GLY A 1 163 ? -16.543 15.069  67.862 1   33.157  ? 152 GLY A HA2  1 
ATOM   2245 H  HA3  . GLY A 1 163 ? -17.388 15.25   66.526 1   32.919  ? 152 GLY A HA3  1 
ATOM   2246 N  N    . PHE A 1 164 ? -14.169 15.499  66.338 1   33.371  ? 153 PHE A N    1 
ATOM   2247 C  CA   . PHE A 1 164 ? -12.963 15.031  65.681 1   28.915  ? 153 PHE A CA   1 
ATOM   2248 C  C    . PHE A 1 164 ? -12.927 15.434  64.214 1   33.779  ? 153 PHE A C    1 
ATOM   2249 O  O    . PHE A 1 164 ? -12.057 14.954  63.478 1   33.516  ? 153 PHE A O    1 
ATOM   2250 C  CB   . PHE A 1 164 ? -12.764 13.508  65.744 1   39.232  ? 153 PHE A CB   1 
ATOM   2251 C  CG   . PHE A 1 164 ? -12.962 12.927  67.132 1   44.762  ? 153 PHE A CG   1 
ATOM   2252 C  CD1  . PHE A 1 164 ? -12.231 13.442  68.21  1   48.478  ? 153 PHE A CD1  1 
ATOM   2253 C  CD2  . PHE A 1 164 ? -13.908 11.92   67.351 1   55.234  ? 153 PHE A CD2  1 
ATOM   2254 C  CE1  . PHE A 1 164 ? -12.445 12.981  69.506 1   62.193  ? 153 PHE A CE1  1 
ATOM   2255 C  CE2  . PHE A 1 164 ? -14.097 11.432  68.647 1   68.477  ? 153 PHE A CE2  1 
ATOM   2256 C  CZ   . PHE A 1 164 ? -13.402 11.995  69.724 1   68.626  ? 153 PHE A CZ   1 
ATOM   2257 H  H    . PHE A 1 164 ? -14.096 16.206  66.912 1   32.781  ? 153 PHE A H    1 
ATOM   2258 H  HA   . PHE A 1 164 ? -12.188 15.457  66.134 1   32.487  ? 153 PHE A HA   1 
ATOM   2259 H  HB2  . PHE A 1 164 ? -13.394 13.079  65.123 1   37.839  ? 153 PHE A HB2  1 
ATOM   2260 H  HB3  . PHE A 1 164 ? -11.853 13.298  65.441 1   37.718  ? 153 PHE A HB3  1 
ATOM   2261 H  HD1  . PHE A 1 164 ? -11.619 14.145  68.06  1   50.332  ? 153 PHE A HD1  1 
ATOM   2262 H  HD2  . PHE A 1 164 ? -14.407 11.571  66.63  1   55.265  ? 153 PHE A HD2  1 
ATOM   2263 H  HE1  . PHE A 1 164 ? -11.949 13.336  70.227 1   59.912  ? 153 PHE A HE1  1 
ATOM   2264 H  HE2  . PHE A 1 164 ? -14.739 10.757  68.804 1   64.826  ? 153 PHE A HE2  1 
ATOM   2265 H  HZ   . PHE A 1 164 ? -13.515 11.638  70.591 1   66.601  ? 153 PHE A HZ   1 
ATOM   2266 N  N    . CYS A 1 165 ? -13.812 16.349  63.796 1   28.974  ? 154 CYS A N    1 
ATOM   2267 C  CA   . CYS A 1 165 ? -13.937 16.732  62.379 1   28.972  ? 154 CYS A CA   1 
ATOM   2268 C  C    . CYS A 1 165 ? -13.432 18.168  62.243 1   30.815  ? 154 CYS A C    1 
ATOM   2269 O  O    . CYS A 1 165 ? -13.759 18.998  63.079 1   35.184  ? 154 CYS A O    1 
ATOM   2270 C  CB   . CYS A 1 165 ? -15.424 16.675  61.935 1   31.759  ? 154 CYS A CB   1 
ATOM   2271 S  SG   . CYS A 1 165 ? -16.194 15.039  62.039 1   36.733  ? 154 CYS A SG   1 
ATOM   2272 H  H    . CYS A 1 165 ? -14.346 16.767  64.407 1   30.098  ? 154 CYS A H    1 
ATOM   2273 H  HA   . CYS A 1 165 ? -13.375 16.132  61.828 1   29.862  ? 154 CYS A HA   1 
ATOM   2274 H  HB2  . CYS A 1 165 ? -15.945 17.297  62.489 1   31.958  ? 154 CYS A HB2  1 
ATOM   2275 H  HB3  . CYS A 1 165 ? -15.487 16.984  61.004 1   31.977  ? 154 CYS A HB3  1 
ATOM   2276 H  HG   . CYS A 1 165 ? -17.297 15.347  61.64  0   36.86   ? 154 CYS A HG   1 
ATOM   2277 N  N    . PHE A 1 166 ? -12.606 18.479  61.25  1   34.623  ? 155 PHE A N    1 
ATOM   2278 C  CA   . PHE A 1 166 ? -12.022 19.795  61.14  1   30.197  ? 155 PHE A CA   1 
ATOM   2279 C  C    . PHE A 1 166 ? -12.428 20.536  59.855 1   36.368  ? 155 PHE A C    1 
ATOM   2280 O  O    . PHE A 1 166 ? -12.334 21.762  59.786 1   34.905  ? 155 PHE A O    1 
ATOM   2281 C  CB   . PHE A 1 166 ? -10.469 19.666  61.176 1   30.87   ? 155 PHE A CB   1 
ATOM   2282 C  CG   . PHE A 1 166 ? -9.996  19.209  62.546 1   36.298  ? 155 PHE A CG   1 
ATOM   2283 C  CD1  . PHE A 1 166 ? -9.802  20.13   63.569 1   37.39   ? 155 PHE A CD1  1 
ATOM   2284 C  CD2  . PHE A 1 166 ? -9.833  17.859  62.837 1   37.32   ? 155 PHE A CD2  1 
ATOM   2285 C  CE1  . PHE A 1 166 ? -9.505  19.719  64.844 1   36.43   ? 155 PHE A CE1  1 
ATOM   2286 C  CE2  . PHE A 1 166 ? -9.49   17.446  64.118 1   37.465  ? 155 PHE A CE2  1 
ATOM   2287 C  CZ   . PHE A 1 166 ? -9.364  18.372  65.121 1   36.219  ? 155 PHE A CZ   1 
ATOM   2288 H  H    . PHE A 1 166 ? -12.389 17.844  60.63  1   32.621  ? 155 PHE A H    1 
ATOM   2289 H  HA   . PHE A 1 166 ? -12.309 20.338  61.92  1   32.227  ? 155 PHE A HA   1 
ATOM   2290 H  HB2  . PHE A 1 166 ? -10.185 19.013  60.498 1   31.895  ? 155 PHE A HB2  1 
ATOM   2291 H  HB3  . PHE A 1 166 ? -10.07  20.539  60.967 1   31.954  ? 155 PHE A HB3  1 
ATOM   2292 H  HD1  . PHE A 1 166 ? -9.958  21.046  63.401 1   36.867  ? 155 PHE A HD1  1 
ATOM   2293 H  HD2  . PHE A 1 166 ? -9.976  17.217  62.16  1   37.066  ? 155 PHE A HD2  1 
ATOM   2294 H  HE1  . PHE A 1 166 ? -9.371  20.358  65.526 1   36.599  ? 155 PHE A HE1  1 
ATOM   2295 H  HE2  . PHE A 1 166 ? -9.383  16.527  64.306 1   37.11   ? 155 PHE A HE2  1 
ATOM   2296 H  HZ   . PHE A 1 166 ? -9.084  18.098  65.978 1   36.572  ? 155 PHE A HZ   1 
ATOM   2297 N  N    . LEU A 1 167 ? -12.71  19.816  58.778 1   33.94   ? 156 LEU A N    1 
ATOM   2298 C  CA   . LEU A 1 167 ? -13.213 20.404  57.534 1   32.201  ? 156 LEU A CA   1 
ATOM   2299 C  C    . LEU A 1 167 ? -14.462 19.63   57.159 1   38.733  ? 156 LEU A C    1 
ATOM   2300 O  O    . LEU A 1 167 ? -14.554 18.434  57.514 1   33.027  ? 156 LEU A O    1 
ATOM   2301 C  CB   . LEU A 1 167 ? -12.197 20.302  56.417 1   30.903  ? 156 LEU A CB   1 
ATOM   2302 C  CG   . LEU A 1 167 ? -10.925 21.111  56.653 1   35.83   ? 156 LEU A CG   1 
ATOM   2303 C  CD1  . LEU A 1 167 ? -10.037 20.764  55.508 1   33.89   ? 156 LEU A CD1  1 
ATOM   2304 C  CD2  . LEU A 1 167 ? -11.231 22.646  56.747 1   35.118  ? 156 LEU A CD2  1 
ATOM   2305 H  H    . LEU A 1 167 ? -12.574 18.913  58.803 1   34.088  ? 156 LEU A H    1 
ATOM   2306 H  HA   . LEU A 1 167 ? -13.45  21.353  57.69  1   33.455  ? 156 LEU A HA   1 
ATOM   2307 H  HB2  . LEU A 1 167 ? -11.953 19.354  56.308 1   32.295  ? 156 LEU A HB2  1 
ATOM   2308 H  HB3  . LEU A 1 167 ? -12.619 20.615  55.584 1   32.32   ? 156 LEU A HB3  1 
ATOM   2309 H  HG   . LEU A 1 167 ? -10.502 20.808  57.498 1   34.39   ? 156 LEU A HG   1 
ATOM   2310 H  HD11 . LEU A 1 167 ? -9.857  19.81   55.513 1   34.391  ? 156 LEU A HD11 1 
ATOM   2311 H  HD12 . LEU A 1 167 ? -9.2    21.251  55.587 1   34.439  ? 156 LEU A HD12 1 
ATOM   2312 H  HD13 . LEU A 1 167 ? -10.473 21.006  54.673 1   34.41   ? 156 LEU A HD13 1 
ATOM   2313 H  HD21 . LEU A 1 167 ? -11.681 22.839  57.585 1   35.289  ? 156 LEU A HD21 1 
ATOM   2314 H  HD22 . LEU A 1 167 ? -11.803 22.908  56.006 1   35.313  ? 156 LEU A HD22 1 
ATOM   2315 H  HD23 . LEU A 1 167 ? -10.399 23.146  56.704 1   35.313  ? 156 LEU A HD23 1 
ATOM   2316 N  N    . ALA A 1 168 ? -15.39  20.291  56.44  1   34.756  ? 157 ALA A N    1 
ATOM   2317 C  CA   . ALA A 1 168 ? -16.626 19.611  56.057 1   32.734  ? 157 ALA A CA   1 
ATOM   2318 C  C    . ALA A 1 168 ? -16.376 18.877  54.742 1   39.868  ? 157 ALA A C    1 
ATOM   2319 O  O    . ALA A 1 168 ? -16.702 19.319  53.665 1   36.492  ? 157 ALA A O    1 
ATOM   2320 C  CB   . ALA A 1 168 ? -17.798 20.569  56.03  1   34.229  ? 157 ALA A CB   1 
ATOM   2321 H  H    . ALA A 1 168 ? -15.249 21.153  56.177 1   35.126  ? 157 ALA A H    1 
ATOM   2322 H  HA   . ALA A 1 168 ? -16.816 18.921  56.75  1   34.66   ? 157 ALA A HA   1 
ATOM   2323 H  HB1  . ALA A 1 168 ? -17.942 20.934  56.919 1   33.791  ? 157 ALA A HB1  1 
ATOM   2324 H  HB2  . ALA A 1 168 ? -17.612 21.295  55.41  1   33.791  ? 157 ALA A HB2  1 
ATOM   2325 H  HB3  . ALA A 1 168 ? -18.598 20.098  55.742 1   33.827  ? 157 ALA A HB3  1 
ATOM   2326 N  N    . ASN A 1 169 ? -15.893 17.65   54.843 1   35.971  ? 158 ASN A N    1 
ATOM   2327 C  CA   . ASN A 1 169 ? -15.441 16.931  53.68  1   35.219  ? 158 ASN A CA   1 
ATOM   2328 C  C    . ASN A 1 169 ? -16.51  16.823  52.601 1   33.931  ? 158 ASN A C    1 
ATOM   2329 O  O    . ASN A 1 169 ? -16.254 17.104  51.457 1   34.427  ? 158 ASN A O    1 
ATOM   2330 C  CB   . ASN A 1 169 ? -14.922 15.542  54.041 1   39.017  ? 158 ASN A CB   1 
ATOM   2331 C  CG   . ASN A 1 169 ? -13.67  15.567  54.91  1   33.639  ? 158 ASN A CG   1 
ATOM   2332 O  OD1  . ASN A 1 169 ? -12.87  16.496  54.861 1   33.933  ? 158 ASN A OD1  1 
ATOM   2333 N  ND2  . ASN A 1 169 ? -13.471 14.529  55.707 1   35.921  ? 158 ASN A ND2  1 
ATOM   2334 H  H    . ASN A 1 169 ? -15.843 17.247  55.662 1   36.617  ? 158 ASN A H    1 
ATOM   2335 H  HA   . ASN A 1 169 ? -14.684 17.432  53.299 1   35.776  ? 158 ASN A HA   1 
ATOM   2336 H  HB2  . ASN A 1 169 ? -15.626 15.056  54.516 1   36.835  ? 158 ASN A HB2  1 
ATOM   2337 H  HB3  . ASN A 1 169 ? -14.725 15.053  53.217 1   36.83   ? 158 ASN A HB3  1 
ATOM   2338 H  HD21 . ASN A 1 169 ? -12.846 14.568  56.336 1   35.201  ? 158 ASN A HD21 1 
ATOM   2339 H  HD22 . ASN A 1 169 ? -13.96  13.795  55.612 1   35.239  ? 158 ASN A HD22 1 
ATOM   2340 N  N    . ILE A 1 170 ? -17.646 16.221  52.895 1   35.2    ? 159 ILE A N    1 
ATOM   2341 C  CA   . ILE A 1 170 ? -18.642 16.026  51.868 1   36.605  ? 159 ILE A CA   1 
ATOM   2342 C  C    . ILE A 1 170 ? -19.181 17.354  51.308 1   36.365  ? 159 ILE A C    1 
ATOM   2343 O  O    . ILE A 1 170 ? -19.286 17.537  50.106 1   34.048  ? 159 ILE A O    1 
ATOM   2344 C  CB   . ILE A 1 170 ? -19.718 15.152  52.477 1   38.661  ? 159 ILE A CB   1 
ATOM   2345 C  CG1  . ILE A 1 170 ? -19.186 13.734  52.505 1   45.682  ? 159 ILE A CG1  1 
ATOM   2346 C  CG2  . ILE A 1 170 ? -21.03  15.218  51.692 1   45.348  ? 159 ILE A CG2  1 
ATOM   2347 C  CD1  . ILE A 1 170 ? -20.156 12.728  53.141 1   39.826  ? 159 ILE A CD1  1 
ATOM   2348 H  H    . ILE A 1 170 ? -17.806 15.927  53.746 1   35.369  ? 159 ILE A H    1 
ATOM   2349 H  HA   . ILE A 1 170 ? -18.229 15.532  51.133 1   36.713  ? 159 ILE A HA   1 
ATOM   2350 H  HB   . ILE A 1 170 ? -19.882 15.438  53.395 1   40.555  ? 159 ILE A HB   1 
ATOM   2351 H  HG12 . ILE A 1 170 ? -18.994 13.449  51.588 1   42.52   ? 159 ILE A HG12 1 
ATOM   2352 H  HG13 . ILE A 1 170 ? -18.345 13.72   53.006 1   42.477  ? 159 ILE A HG13 1 
ATOM   2353 H  HG21 . ILE A 1 170 ? -21.663 14.576  52.054 1   43.225  ? 159 ILE A HG21 1 
ATOM   2354 H  HG22 . ILE A 1 170 ? -20.862 15.011  50.757 1   43.227  ? 159 ILE A HG22 1 
ATOM   2355 H  HG23 . ILE A 1 170 ? -21.409 16.111  51.76  1   43.217  ? 159 ILE A HG23 1 
ATOM   2356 H  HD11 . ILE A 1 170 ? -20.6   13.144  53.904 1   41.448  ? 159 ILE A HD11 1 
ATOM   2357 H  HD12 . ILE A 1 170 ? -19.662 11.943  53.444 1   41.42   ? 159 ILE A HD12 1 
ATOM   2358 H  HD13 . ILE A 1 170 ? -20.825 12.456  52.486 1   41.449  ? 159 ILE A HD13 1 
ATOM   2359 N  N    . PRO A 1 171 ? -19.539 18.343  52.115 1   36.622  ? 160 PRO A N    1 
ATOM   2360 C  CA   . PRO A 1 171 ? -19.966 19.629  51.544 1   34.934  ? 160 PRO A CA   1 
ATOM   2361 C  C    . PRO A 1 171 ? -18.951 20.326  50.677 1   34.759  ? 160 PRO A C    1 
ATOM   2362 O  O    . PRO A 1 171 ? -19.267 20.834  49.63  1   35.983  ? 160 PRO A O    1 
ATOM   2363 C  CB   . PRO A 1 171 ? -20.293 20.414  52.77  1   35.288  ? 160 PRO A CB   1 
ATOM   2364 C  CG   . PRO A 1 171 ? -20.791 19.394  53.793 1   36.283  ? 160 PRO A CG   1 
ATOM   2365 C  CD   . PRO A 1 171 ? -19.885 18.176  53.543 1   39.006  ? 160 PRO A CD   1 
ATOM   2366 H  HA   . PRO A 1 171 ? -20.794 19.479  51.025 1   35.306  ? 160 PRO A HA   1 
ATOM   2367 H  HB2  . PRO A 1 171 ? -19.495 20.884  53.108 1   35.421  ? 160 PRO A HB2  1 
ATOM   2368 H  HB3  . PRO A 1 171 ? -20.991 21.084  52.579 1   35.424  ? 160 PRO A HB3  1 
ATOM   2369 H  HG2  . PRO A 1 171 ? -20.686 19.73   54.708 1   36.624  ? 160 PRO A HG2  1 
ATOM   2370 H  HG3  . PRO A 1 171 ? -21.733 19.17   53.64  1   36.64   ? 160 PRO A HG3  1 
ATOM   2371 H  HD2  . PRO A 1 171 ? -19.085 18.203  54.112 1   37.828  ? 160 PRO A HD2  1 
ATOM   2372 H  HD3  . PRO A 1 171 ? -20.372 17.342  53.699 1   37.862  ? 160 PRO A HD3  1 
ATOM   2373 N  N    . ILE A 1 172 ? -17.686 20.207  51.022 1   36.685  ? 161 ILE A N    1 
ATOM   2374 C  CA   . ILE A 1 172 ? -16.657 20.765  50.194 1   30.568  ? 161 ILE A CA   1 
ATOM   2375 C  C    . ILE A 1 172 ? -16.656 20.136  48.827 1   35.405  ? 161 ILE A C    1 
ATOM   2376 O  O    . ILE A 1 172 ? -16.455 20.85   47.885 1   33.985  ? 161 ILE A O    1 
ATOM   2377 C  CB   . ILE A 1 172 ? -15.305 20.656  50.884 1   35.704  ? 161 ILE A CB   1 
ATOM   2378 C  CG1  . ILE A 1 172 ? -15.253 21.608  52.041 1   38.281  ? 161 ILE A CG1  1 
ATOM   2379 C  CG2  . ILE A 1 172 ? -14.115 20.87   49.944 1   33.157  ? 161 ILE A CG2  1 
ATOM   2380 C  CD1  . ILE A 1 172 ? -14.185 21.22   53.075 1   41.529  ? 161 ILE A CD1  1 
ATOM   2381 H  H    . ILE A 1 172 ? -17.457 19.775  51.794 1   34.805  ? 161 ILE A H    1 
ATOM   2382 H  HA   . ILE A 1 172 ? -16.852 21.717  50.083 1   33.543  ? 161 ILE A HA   1 
ATOM   2383 H  HB   . ILE A 1 172 ? -15.234 19.75   51.247 1   34.736  ? 161 ILE A HB   1 
ATOM   2384 H  HG12 . ILE A 1 172 ? -15.06  22.508  51.705 1   38.314  ? 161 ILE A HG12 1 
ATOM   2385 H  HG13 . ILE A 1 172 ? -16.126 21.63   52.481 1   38.262  ? 161 ILE A HG13 1 
ATOM   2386 H  HG21 . ILE A 1 172 ? -13.306 21.003  50.465 1   33.996  ? 161 ILE A HG21 1 
ATOM   2387 H  HG22 . ILE A 1 172 ? -14.274 21.654  49.391 1   33.923  ? 161 ILE A HG22 1 
ATOM   2388 H  HG23 . ILE A 1 172 ? -14.004 20.091  49.375 1   33.945  ? 161 ILE A HG23 1 
ATOM   2389 H  HD11 . ILE A 1 172 ? -14.229 20.262  53.253 1   40.472  ? 161 ILE A HD11 1 
ATOM   2390 H  HD12 . ILE A 1 172 ? -14.344 21.71   53.904 1   40.523  ? 161 ILE A HD12 1 
ATOM   2391 H  HD13 . ILE A 1 172 ? -13.299 21.444  52.732 1   40.485  ? 161 ILE A HD13 1 
ATOM   2392 N  N    . ALA A 1 173 ? -16.715 18.798  48.75  1   32.564  ? 162 ALA A N    1 
ATOM   2393 C  CA   . ALA A 1 173 ? -16.733 18.1    47.501 1   32.46   ? 162 ALA A CA   1 
ATOM   2394 C  C    . ALA A 1 173 ? -17.999 18.437  46.682 1   37.721  ? 162 ALA A C    1 
ATOM   2395 O  O    . ALA A 1 173 ? -17.951 18.458  45.442 1   36.317  ? 162 ALA A O    1 
ATOM   2396 C  CB   . ALA A 1 173 ? -16.705 16.618  47.802 1   35.024  ? 162 ALA A CB   1 
ATOM   2397 H  H    . ALA A 1 173 ? -16.741 18.311  49.523 1   33.217  ? 162 ALA A H    1 
ATOM   2398 H  HA   . ALA A 1 173 ? -15.93  18.357  46.973 1   33.865  ? 162 ALA A HA   1 
ATOM   2399 H  HB1  . ALA A 1 173 ? -15.867 16.389  48.238 1   34.255  ? 162 ALA A HB1  1 
ATOM   2400 H  HB2  . ALA A 1 173 ? -17.445 16.39   48.39  1   34.249  ? 162 ALA A HB2  1 
ATOM   2401 H  HB3  . ALA A 1 173 ? -16.785 16.114  46.975 1   34.295  ? 162 ALA A HB3  1 
ATOM   2402 N  N    . VAL A 1 174 ? -19.149 18.504  47.357 1   36.033  ? 163 VAL A N    1 
ATOM   2403 C  CA   . VAL A 1 174 ? -20.422 18.812  46.731 1   36.175  ? 163 VAL A CA   1 
ATOM   2404 C  C    . VAL A 1 174 ? -20.428 20.244  46.209 1   41.264  ? 163 VAL A C    1 
ATOM   2405 O  O    . VAL A 1 174 ? -20.656 20.486  45.028 1   41.575  ? 163 VAL A O    1 
ATOM   2406 C  CB   . VAL A 1 174 ? -21.558 18.639  47.699 1   37.503  ? 163 VAL A CB   1 
ATOM   2407 C  CG1  . VAL A 1 174 ? -22.818 19.327  47.194 1   47.892  ? 163 VAL A CG1  1 
ATOM   2408 C  CG2  . VAL A 1 174 ? -21.792 17.163  47.927 1   42.188  ? 163 VAL A CG2  1 
ATOM   2409 H  H    . VAL A 1 174 ? -19.138 18.34   48.257 1   36.437  ? 163 VAL A H    1 
ATOM   2410 H  HA   . VAL A 1 174 ? -20.555 18.203  45.978 1   37.321  ? 163 VAL A HA   1 
ATOM   2411 H  HB   . VAL A 1 174 ? -21.291 19.054  48.553 1   39.807  ? 163 VAL A HB   1 
ATOM   2412 H  HG11 . VAL A 1 174 ? -22.917 19.168  46.239 1   44.485  ? 163 VAL A HG11 1 
ATOM   2413 H  HG12 . VAL A 1 174 ? -22.759 20.282  47.359 1   44.561  ? 163 VAL A HG12 1 
ATOM   2414 H  HG13 . VAL A 1 174 ? -23.591 18.968  47.66  1   44.526  ? 163 VAL A HG13 1 
ATOM   2415 H  HG21 . VAL A 1 174 ? -22.48  17.045  48.603 1   40.716  ? 163 VAL A HG21 1 
ATOM   2416 H  HG22 . VAL A 1 174 ? -20.969 16.745  48.227 1   40.666  ? 163 VAL A HG22 1 
ATOM   2417 H  HG23 . VAL A 1 174 ? -22.081 16.749  47.096 1   40.698  ? 163 VAL A HG23 1 
ATOM   2418 N  N    . GLU A 1 175 ? -20.039 21.193  47.035 1   37.929  ? 164 GLU A N    1 
ATOM   2419 C  CA   . GLU A 1 175 ? -19.984 22.575  46.549 1   40.837  ? 164 GLU A CA   1 
ATOM   2420 C  C    . GLU A 1 175 ? -19.056 22.701  45.355 1   45.956  ? 164 GLU A C    1 
ATOM   2421 O  O    . GLU A 1 175 ? -19.324 23.459  44.454 1   47.223  ? 164 GLU A O    1 
ATOM   2422 C  CB   . GLU A 1 175 ? -19.62  23.606  47.606 1   34.844  ? 164 GLU A CB   1 
ATOM   2423 C  CG   . GLU A 1 175 ? -20.699 23.754  48.677 1   44.834  ? 164 GLU A CG   1 
ATOM   2424 C  CD   . GLU A 1 175 ? -22.128 23.87   48.139 1   47.799  ? 164 GLU A CD   1 
ATOM   2425 O  OE1  . GLU A 1 175 ? -22.524 24.988  47.826 1   50.942  ? 164 GLU A OE1  1 
ATOM   2426 O  OE2  . GLU A 1 175 ? -22.808 22.833  47.982 1   53.68   ? 164 GLU A OE2  1 
ATOM   2427 H  H    . GLU A 1 175 ? -19.808 21.004  47.899 1   39.298  ? 164 GLU A H    1 
ATOM   2428 H  HA   . GLU A 1 175 ? -20.891 22.808  46.229 1   40.11   ? 164 GLU A HA   1 
ATOM   2429 H  HB2  . GLU A 1 175 ? -18.776 23.342  48.03  1   38.263  ? 164 GLU A HB2  1 
ATOM   2430 H  HB3  . GLU A 1 175 ? -19.479 24.473  47.171 1   38.294  ? 164 GLU A HB3  1 
ATOM   2431 H  HG2  . GLU A 1 175 ? -20.658 22.981  49.279 1   42.898  ? 164 GLU A HG2  1 
ATOM   2432 H  HG3  . GLU A 1 175 ? -20.505 24.552  49.214 1   42.938  ? 164 GLU A HG3  1 
ATOM   2433 N  N    . ARG A 1 176 ? -17.976 21.944  45.346 1   48.279  ? 165 ARG A N    1 
ATOM   2434 C  CA   . ARG A 1 176 ? -17.021 22.06   44.27  1   47.779  ? 165 ARG A CA   1 
ATOM   2435 C  C    . ARG A 1 176 ? -17.605 21.462  43.004 1   45.548  ? 165 ARG A C    1 
ATOM   2436 O  O    . ARG A 1 176 ? -17.268 21.9    41.93  1   43.948  ? 165 ARG A O    1 
ATOM   2437 C  CB   . ARG A 1 176 ? -15.715 21.341  44.584 1   41.863  ? 165 ARG A CB   1 
ATOM   2438 C  CG   . ARG A 1 176 ? -14.725 21.16   43.441 1   43.378  ? 165 ARG A CG   1 
ATOM   2439 C  CD   . ARG A 1 176 ? -13.448 20.539  43.97  1   44.171  ? 165 ARG A CD   1 
ATOM   2440 N  NE   . ARG A 1 176 ? -12.424 20.166  42.976 1   49.194  ? 165 ARG A NE   1 
ATOM   2441 C  CZ   . ARG A 1 176 ? -12.555 19.169  42.109 1   53.26   ? 165 ARG A CZ   1 
ATOM   2442 N  NH1  . ARG A 1 176 ? -13.673 18.461  42.071 1   56.07   ? 165 ARG A NH1  1 
ATOM   2443 N  NH2  . ARG A 1 176 ? -11.572 18.894  41.274 1   51.561  ? 165 ARG A NH2  1 
ATOM   2444 H  H    . ARG A 1 176 ? -17.817 21.352  46.024 1   47.371  ? 165 ARG A H    1 
ATOM   2445 H  HA   . ARG A 1 176 ? -16.834 23.02   44.114 1   46.355  ? 165 ARG A HA   1 
ATOM   2446 H  HB2  . ARG A 1 176 ? -15.264 21.832  45.304 1   43.606  ? 165 ARG A HB2  1 
ATOM   2447 H  HB3  . ARG A 1 176 ? -15.938 20.453  44.936 1   43.558  ? 165 ARG A HB3  1 
ATOM   2448 H  HG2  . ARG A 1 176 ? -15.111 20.572  42.756 1   43.285  ? 165 ARG A HG2  1 
ATOM   2449 H  HG3  . ARG A 1 176 ? -14.522 22.031  43.036 1   43.224  ? 165 ARG A HG3  1 
ATOM   2450 H  HD2  . ARG A 1 176 ? -13.052 21.165  44.606 1   45.142  ? 165 ARG A HD2  1 
ATOM   2451 H  HD3  . ARG A 1 176 ? -13.696 19.738  44.476 1   45.125  ? 165 ARG A HD3  1 
ATOM   2452 H  HE   . ARG A 1 176 ? -11.687 20.631  42.957 1   48.949  ? 165 ARG A HE   1 
ATOM   2453 H  HH11 . ARG A 1 176 ? -13.908 17.973  42.77  1   55.12   ? 165 ARG A HH11 1 
ATOM   2454 H  HH12 . ARG A 1 176 ? -14.179 18.48   41.347 1   55.173  ? 165 ARG A HH12 1 
ATOM   2455 H  HH21 . ARG A 1 176 ? -10.842 19.393  41.266 1   52.034  ? 165 ARG A HH21 1 
ATOM   2456 H  HH22 . ARG A 1 176 ? -11.647 18.208  40.721 1   52.095  ? 165 ARG A HH22 1 
ATOM   2457 N  N    . ALA A 1 177 ? -18.357 20.383  43.133 1   44.025  ? 166 ALA A N    1 
ATOM   2458 C  CA   . ALA A 1 177 ? -18.956 19.764  41.968 1   49.16   ? 166 ALA A CA   1 
ATOM   2459 C  C    . ALA A 1 177 ? -20.123 20.624  41.433 1   46.569  ? 166 ALA A C    1 
ATOM   2460 O  O    . ALA A 1 177 ? -20.334 20.678  40.242 1   40.907  ? 166 ALA A O    1 
ATOM   2461 C  CB   . ALA A 1 177 ? -19.344 18.337  42.252 1   42.909  ? 166 ALA A CB   1 
ATOM   2462 H  H    . ALA A 1 177 ? -18.499 20.014  43.958 1   45.518  ? 166 ALA A H    1 
ATOM   2463 H  HA   . ALA A 1 177 ? -18.26  19.748  41.256 1   46.602  ? 166 ALA A HA   1 
ATOM   2464 H  HB1  . ALA A 1 177 ? -18.556 17.829  42.509 1   44.683  ? 166 ALA A HB1  1 
ATOM   2465 H  HB2  . ALA A 1 177 ? -19.993 18.312  42.976 1   44.683  ? 166 ALA A HB2  1 
ATOM   2466 H  HB3  . ALA A 1 177 ? -19.736 17.94   41.456 1   44.683  ? 166 ALA A HB3  1 
ATOM   2467 N  N    . LYS A 1 178 ? -20.803 21.385  42.271 1   41.282  ? 167 LYS A N    1 
ATOM   2468 C  CA   . LYS A 1 178 ? -21.797 22.335  41.808 1   45.381  ? 167 LYS A CA   1 
ATOM   2469 C  C    . LYS A 1 178 ? -21.157 23.476  41.026 1   51.094  ? 167 LYS A C    1 
ATOM   2470 O  O    . LYS A 1 178 ? -21.682 23.935  40.041 1   59.118  ? 167 LYS A O    1 
ATOM   2471 C  CB   . LYS A 1 178 ? -22.645 22.893  42.957 1   41.314  ? 167 LYS A CB   1 
ATOM   2472 C  CG   . LYS A 1 178 ? -23.577 21.821  43.476 1   37.928  ? 167 LYS A CG   1 
ATOM   2473 C  CD   . LYS A 1 178 ? -24.42  22.22   44.643 1   46.467  ? 167 LYS A CD   1 
ATOM   2474 C  CE   . LYS A 1 178 ? -25.295 21.061  44.831 1   48.312  ? 167 LYS A CE   1 
ATOM   2475 N  NZ   . LYS A 1 178 ? -26.577 21.12   44.139 1   56.721  ? 167 LYS A NZ   1 
ATOM   2476 H  H    . LYS A 1 178 ? -20.652 21.31   43.169 1   43.428  ? 167 LYS A H    1 
ATOM   2477 H  HA   . LYS A 1 178 ? -22.411 21.855  41.196 1   44.759  ? 167 LYS A HA   1 
ATOM   2478 H  HB2  . LYS A 1 178 ? -22.062 23.197  43.685 1   41.382  ? 167 LYS A HB2  1 
ATOM   2479 H  HB3  . LYS A 1 178 ? -23.173 23.657  42.641 1   41.421  ? 167 LYS A HB3  1 
ATOM   2480 H  HG2  . LYS A 1 178 ? -24.165 21.544  42.741 1   40.771  ? 167 LYS A HG2  1 
ATOM   2481 H  HG3  . LYS A 1 178 ? -23.035 21.042  43.729 1   40.692  ? 167 LYS A HG3  1 
ATOM   2482 H  HD2  . LYS A 1 178 ? -23.869 22.363  45.443 1   44.792  ? 167 LYS A HD2  1 
ATOM   2483 H  HD3  . LYS A 1 178 ? -24.953 23.019  44.436 1   44.836  ? 167 LYS A HD3  1 
ATOM   2484 H  HE2  . LYS A 1 178 ? -24.835 20.248  44.555 1   49.493  ? 167 LYS A HE2  1 
ATOM   2485 H  HE3  . LYS A 1 178 ? -25.473 20.973  45.784 1   49.674  ? 167 LYS A HE3  1 
ATOM   2486 H  HZ1  . LYS A 1 178 ? -26.442 21.139  43.243 1   53.866  ? 167 LYS A HZ1  1 
ATOM   2487 H  HZ2  . LYS A 1 178 ? -27.025 21.867  44.388 1   53.897  ? 167 LYS A HZ2  1 
ATOM   2488 H  HZ3  . LYS A 1 178 ? -27.072 20.392  44.35  1   53.946  ? 167 LYS A HZ3  1 
ATOM   2489 N  N    . ALA A 1 179 ? -20.012 23.938  41.455 1   55.641  ? 168 ALA A N    1 
ATOM   2490 C  CA   . ALA A 1 179 ? -19.394 25.026  40.752 1   51.205  ? 168 ALA A CA   1 
ATOM   2491 C  C    . ALA A 1 179 ? -18.646 24.564  39.506 1   53.144  ? 168 ALA A C    1 
ATOM   2492 O  O    . ALA A 1 179 ? -18.332 25.407  38.721 1   48.18   ? 168 ALA A O    1 
ATOM   2493 C  CB   . ALA A 1 179 ? -18.461 25.765  41.695 1   58.32   ? 168 ALA A CB   1 
ATOM   2494 H  H    . ALA A 1 179 ? -19.607 23.584  42.194 1   53.385  ? 168 ALA A H    1 
ATOM   2495 H  HA   . ALA A 1 179 ? -20.111 25.655  40.462 1   53.679  ? 168 ALA A HA   1 
ATOM   2496 H  HB1  . ALA A 1 179 ? -18.966 26.115  42.448 1   56.122  ? 168 ALA A HB1  1 
ATOM   2497 H  HB2  . ALA A 1 179 ? -17.778 25.156  42.023 1   56.121  ? 168 ALA A HB2  1 
ATOM   2498 H  HB3  . ALA A 1 179 ? -18.035 26.501  41.224 1   56.121  ? 168 ALA A HB3  1 
ATOM   2499 N  N    . GLN A 1 180 ? -18.2   23.316  39.332 1   46.063  ? 169 GLN A N    1 
ATOM   2500 C  CA   . GLN A 1 180 ? -17.259 23.082  38.265 1   49.097  ? 169 GLN A CA   1 
ATOM   2501 C  C    . GLN A 1 180 ? -17.727 21.974  37.34  1   50.829  ? 169 GLN A C    1 
ATOM   2502 O  O    . GLN A 1 180 ? -17.054 21.717  36.361 1   49.204  ? 169 GLN A O    1 
ATOM   2503 C  CB   . GLN A 1 180 ? -15.885 22.633  38.757 1   55.923  ? 169 GLN A CB   1 
ATOM   2504 C  CG   . GLN A 1 180 ? -15.012 23.732  39.355 1   69.86   ? 169 GLN A CG   1 
ATOM   2505 C  CD   . GLN A 1 180 ? -13.728 23.183  39.97  1   72.014  ? 169 GLN A CD   1 
ATOM   2506 O  OE1  . GLN A 1 180 ? -13.327 22.016  39.814 1   55.976  ? 169 GLN A OE1  1 
ATOM   2507 N  NE2  . GLN A 1 180 ? -13.081 24.03   40.745 1   67.1    ? 169 GLN A NE2  1 
ATOM   2508 H  H    . GLN A 1 180 ? -18.448 22.636  39.89  1   48.501  ? 169 GLN A H    1 
ATOM   2509 H  HA   . GLN A 1 180 ? -17.155 23.913  37.736 1   49.975  ? 169 GLN A HA   1 
ATOM   2510 H  HB2  . GLN A 1 180 ? -16.015 21.936  39.433 1   57.098  ? 169 GLN A HB2  1 
ATOM   2511 H  HB3  . GLN A 1 180 ? -15.4   22.228  38.009 1   57.038  ? 169 GLN A HB3  1 
ATOM   2512 H  HG2  . GLN A 1 180 ? -14.778 24.378  38.655 1   66.872  ? 169 GLN A HG2  1 
ATOM   2513 H  HG3  . GLN A 1 180 ? -15.518 24.208  40.047 1   66.88   ? 169 GLN A HG3  1 
ATOM   2514 H  HE21 . GLN A 1 180 ? -12.367 23.76   41.196 1   68.467  ? 169 GLN A HE21 1 
ATOM   2515 H  HE22 . GLN A 1 180 ? -13.358 24.87   40.815 1   68.546  ? 169 GLN A HE22 1 
ATOM   2516 N  N    . LEU A 1 181 ? -18.752 21.217  37.732 1   55.376  ? 170 LEU A N    1 
ATOM   2517 C  CA   . LEU A 1 181 ? -19.16  20.032  36.986 1   58.472  ? 170 LEU A CA   1 
ATOM   2518 C  C    . LEU A 1 181 ? -20.666 20.078  36.737 1   51.082  ? 170 LEU A C    1 
ATOM   2519 O  O    . LEU A 1 181 ? -21.223 19.079  36.338 1   60.114  ? 170 LEU A O    1 
ATOM   2520 C  CB   . LEU A 1 181 ? -18.735 18.765  37.743 1   65.475  ? 170 LEU A CB   1 
ATOM   2521 C  CG   . LEU A 1 181 ? -17.25  18.654  38.115 1   74.208  ? 170 LEU A CG   1 
ATOM   2522 C  CD1  . LEU A 1 181 ? -16.972 17.723  39.304 1   80.786  ? 170 LEU A CD1  1 
ATOM   2523 C  CD2  . LEU A 1 181 ? -16.462 18.224  36.888 1   84.241  ? 170 LEU A CD2  1 
ATOM   2524 H  H    . LEU A 1 181 ? -19.206 21.43   38.495 1   54.825  ? 170 LEU A H    1 
ATOM   2525 H  HA   . LEU A 1 181 ? -18.705 20.045  36.107 1   57.503  ? 170 LEU A HA   1 
ATOM   2526 H  HB2  . LEU A 1 181 ? -19.266 18.711  38.571 1   65.756  ? 170 LEU A HB2  1 
ATOM   2527 H  HB3  . LEU A 1 181 ? -18.975 17.984  37.192 1   65.823  ? 170 LEU A HB3  1 
ATOM   2528 H  HG   . LEU A 1 181 ? -16.932 19.556  38.37  1   75.168  ? 170 LEU A HG   1 
ATOM   2529 H  HD11 . LEU A 1 181 ? -17.567 17.947  40.039 1   78.155  ? 170 LEU A HD11 1 
ATOM   2530 H  HD12 . LEU A 1 181 ? -16.05  17.83   39.591 1   78.647  ? 170 LEU A HD12 1 
ATOM   2531 H  HD13 . LEU A 1 181 ? -17.123 16.801  39.037 1   78.647  ? 170 LEU A HD13 1 
ATOM   2532 H  HD21 . LEU A 1 181 ? -16.558 18.894  36.19  1   81.099  ? 170 LEU A HD21 1 
ATOM   2533 H  HD22 . LEU A 1 181 ? -16.8   17.372  36.567 1   80.962  ? 170 LEU A HD22 1 
ATOM   2534 H  HD23 . LEU A 1 181 ? -15.523 18.132  37.121 1   81.099  ? 170 LEU A HD23 1 
ATOM   2535 N  N    . GLY A 1 182 ? -21.311 21.238  36.936 1   62.358  ? 171 GLY A N    1 
ATOM   2536 C  CA   . GLY A 1 182 ? -22.755 21.391  36.758 1   66.675  ? 171 GLY A CA   1 
ATOM   2537 C  C    . GLY A 1 182 ? -23.564 20.362  37.548 1   62.55   ? 171 GLY A C    1 
ATOM   2538 O  O    . GLY A 1 182 ? -24.491 19.758  37.045 1   53.283  ? 171 GLY A O    1 
ATOM   2539 H  H    . GLY A 1 182 ? -20.829 21.975  37.18  1   60.25   ? 171 GLY A H    1 
ATOM   2540 H  HA2  . GLY A 1 182 ? -23.016 22.298  37.044 1   64.696  ? 171 GLY A HA2  1 
ATOM   2541 H  HA3  . GLY A 1 182 ? -22.968 21.306  35.8   1   64.697  ? 171 GLY A HA3  1 
ATOM   2542 N  N    . LEU A 1 183 ? -23.212 20.119  38.805 1   61.365  ? 172 LEU A N    1 
ATOM   2543 C  CA   . LEU A 1 183 ? -23.976 19.147  39.557 1   53.119  ? 172 LEU A CA   1 
ATOM   2544 C  C    . LEU A 1 183 ? -25.266 19.823  40.022 1   40.388  ? 172 LEU A C    1 
ATOM   2545 O  O    . LEU A 1 183 ? -25.217 20.944  40.548 1   42.134  ? 172 LEU A O    1 
ATOM   2546 C  CB   . LEU A 1 183 ? -23.119 18.602  40.712 1   52.537  ? 172 LEU A CB   1 
ATOM   2547 C  CG   . LEU A 1 183 ? -23.868 17.807  41.784 1   50.132  ? 172 LEU A CG   1 
ATOM   2548 C  CD1  . LEU A 1 183 ? -24.419 16.521  41.225 1   47.683  ? 172 LEU A CD1  1 
ATOM   2549 C  CD2  . LEU A 1 183 ? -23.015 17.546  43.03  1   55.349  ? 172 LEU A CD2  1 
ATOM   2550 H  H    . LEU A 1 183 ? -22.509 20.554  39.195 1   59.497  ? 172 LEU A H    1 
ATOM   2551 H  HA   . LEU A 1 183 ? -24.21  18.397  38.952 1   51.839  ? 172 LEU A HA   1 
ATOM   2552 H  HB2  . LEU A 1 183 ? -22.419 18.024  40.329 1   52.114  ? 172 LEU A HB2  1 
ATOM   2553 H  HB3  . LEU A 1 183 ? -22.672 19.364  41.148 1   52.131  ? 172 LEU A HB3  1 
ATOM   2554 H  HG   . LEU A 1 183 ? -24.643 18.352  42.076 1   50.956  ? 172 LEU A HG   1 
ATOM   2555 H  HD11 . LEU A 1 183 ? -25.076 16.719  40.538 1   48.403  ? 172 LEU A HD11 1 
ATOM   2556 H  HD12 . LEU A 1 183 ? -24.84  16.011  41.937 1   48.407  ? 172 LEU A HD12 1 
ATOM   2557 H  HD13 . LEU A 1 183 ? -23.696 16      40.839 1   48.435  ? 172 LEU A HD13 1 
ATOM   2558 H  HD21 . LEU A 1 183 ? -22.742 18.394  43.42  1   53.766  ? 172 LEU A HD21 1 
ATOM   2559 H  HD22 . LEU A 1 183 ? -22.227 17.035  42.784 1   53.766  ? 172 LEU A HD22 1 
ATOM   2560 H  HD23 . LEU A 1 183 ? -23.535 17.044  43.681 1   53.766  ? 172 LEU A HD23 1 
ATOM   2561 N  N    . GLY A 1 184 ? -26.39  19.114  39.88  1   47.118  ? 173 GLY A N    1 
ATOM   2562 C  CA   . GLY A 1 184 ? -27.717 19.551  40.348 1   43.493  ? 173 GLY A CA   1 
ATOM   2563 C  C    . GLY A 1 184 ? -28.042 18.956  41.732 1   45.927  ? 173 GLY A C    1 
ATOM   2564 O  O    . GLY A 1 184 ? -27.279 19.108  42.669 1   52.113  ? 173 GLY A O    1 
ATOM   2565 H  H    . GLY A 1 184 ? -26.334 18.304  39.462 1   44.905  ? 173 GLY A H    1 
ATOM   2566 H  HA2  . GLY A 1 184 ? -27.737 20.535  40.399 1   44.852  ? 173 GLY A HA2  1 
ATOM   2567 H  HA3  . GLY A 1 184 ? -28.398 19.268  39.697 1   45.037  ? 173 GLY A HA3  1 
ATOM   2568 N  N    . LYS A 1 185 ? -29.22  18.388  41.89  1   44.707  ? 174 LYS A N    1 
ATOM   2569 C  CA   . LYS A 1 185 ? -29.705 17.787  43.107 1   45.542  ? 174 LYS A CA   1 
ATOM   2570 C  C    . LYS A 1 185 ? -28.808 16.623  43.561 1   48.339  ? 174 LYS A C    1 
ATOM   2571 O  O    . LYS A 1 185 ? -28.4   15.762  42.778 1   45.24   ? 174 LYS A O    1 
ATOM   2572 C  CB   . LYS A 1 185 ? -31.117 17.298  42.771 1   47.944  ? 174 LYS A CB   1 
ATOM   2573 C  CG   . LYS A 1 185 ? -32.233 18.348  42.969 1   58.938  ? 174 LYS A CG   1 
ATOM   2574 C  CD   . LYS A 1 185 ? -33.299 18.51   41.885 1   74.59   ? 174 LYS A CD   1 
ATOM   2575 C  CE   . LYS A 1 185 ? -33.711 17.331  41.029 1   84.949  ? 174 LYS A CE   1 
ATOM   2576 N  NZ   . LYS A 1 185 ? -34.935 16.747  41.58  1   80.618  ? 174 LYS A NZ   1 
ATOM   2577 H  H    . LYS A 1 185 ? -29.777 18.382  41.166 1   45.237  ? 174 LYS A H    1 
ATOM   2578 H  HA   . LYS A 1 185 ? -29.739 18.478  43.812 1   46.409  ? 174 LYS A HA   1 
ATOM   2579 H  HB2  . LYS A 1 185 ? -31.132 16.995  41.84  1   49.92   ? 174 LYS A HB2  1 
ATOM   2580 H  HB3  . LYS A 1 185 ? -31.322 16.523  43.337 1   49.7    ? 174 LYS A HB3  1 
ATOM   2581 H  HG2  . LYS A 1 185 ? -32.69  18.138  43.812 1   59.327  ? 174 LYS A HG2  1 
ATOM   2582 H  HG3  . LYS A 1 185 ? -31.801 19.22   43.098 1   59.177  ? 174 LYS A HG3  1 
ATOM   2583 H  HD2  . LYS A 1 185 ? -34.104 18.862  42.324 1   72.945  ? 174 LYS A HD2  1 
ATOM   2584 H  HD3  . LYS A 1 185 ? -32.991 19.223  41.285 1   72.823  ? 174 LYS A HD3  1 
ATOM   2585 H  HE2  . LYS A 1 185 ? -33.881 17.629  40.117 1   81.326  ? 174 LYS A HE2  1 
ATOM   2586 H  HE3  . LYS A 1 185 ? -33.015 16.652  41.007 1   80.694  ? 174 LYS A HE3  1 
ATOM   2587 H  HZ1  . LYS A 1 185 ? -35.63  17.315  41.458 1   81.803  ? 174 LYS A HZ1  1 
ATOM   2588 H  HZ2  . LYS A 1 185 ? -34.831 16.588  42.466 1   81.774  ? 174 LYS A HZ2  1 
ATOM   2589 H  HZ3  . LYS A 1 185 ? -35.115 15.965  41.159 1   81.746  ? 174 LYS A HZ3  1 
ATOM   2590 N  N    . VAL A 1 186 ? -28.53  16.581  44.876 1   54.438  ? 175 VAL A N    1 
ATOM   2591 C  CA   . VAL A 1 186 ? -27.726 15.518  45.461 1   48.825  ? 175 VAL A CA   1 
ATOM   2592 C  C    . VAL A 1 186 ? -28.316 15.15   46.806 1   41.585  ? 175 VAL A C    1 
ATOM   2593 O  O    . VAL A 1 186 ? -28.759 16.029  47.524 1   36.318  ? 175 VAL A O    1 
ATOM   2594 C  CB   . VAL A 1 186 ? -26.243 15.958  45.518 1   47.901  ? 175 VAL A CB   1 
ATOM   2595 C  CG1  . VAL A 1 186 ? -26.077 17.325  46.103 1   50.777  ? 175 VAL A CG1  1 
ATOM   2596 C  CG2  . VAL A 1 186 ? -25.381 14.978  46.289 1   56.818  ? 175 VAL A CG2  1 
ATOM   2597 H  H    . VAL A 1 186 ? -28.854 17.238  45.423 1   51.468  ? 175 VAL A H    1 
ATOM   2598 H  HA   . VAL A 1 186 ? -27.787 14.737  44.88  1   48.1    ? 175 VAL A HA   1 
ATOM   2599 H  HB   . VAL A 1 186 ? -25.912 15.985  44.59  1   50.183  ? 175 VAL A HB   1 
ATOM   2600 H  HG11 . VAL A 1 186 ? -26.474 17.349  46.99  1   49.729  ? 175 VAL A HG11 1 
ATOM   2601 H  HG12 . VAL A 1 186 ? -26.515 17.98   45.535 1   49.89   ? 175 VAL A HG12 1 
ATOM   2602 H  HG13 . VAL A 1 186 ? -25.131 17.537  46.168 1   49.898  ? 175 VAL A HG13 1 
ATOM   2603 H  HG21 . VAL A 1 186 ? -24.443 15.159  46.107 1   53.983  ? 175 VAL A HG21 1 
ATOM   2604 H  HG22 . VAL A 1 186 ? -25.594 14.071  46.014 1   53.954  ? 175 VAL A HG22 1 
ATOM   2605 H  HG23 . VAL A 1 186 ? -25.549 15.075  47.242 1   53.917  ? 175 VAL A HG23 1 
ATOM   2606 N  N    . ALA A 1 187 ? -28.389 13.841  47.096 1   39.788  ? 176 ALA A N    1 
ATOM   2607 C  CA   . ALA A 1 187 ? -28.813 13.383  48.406 1   44.642  ? 176 ALA A CA   1 
ATOM   2608 C  C    . ALA A 1 187 ? -27.618 12.839  49.209 1   40.28   ? 176 ALA A C    1 
ATOM   2609 O  O    . ALA A 1 187 ? -26.742 12.19   48.678 1   39.132  ? 176 ALA A O    1 
ATOM   2610 C  CB   . ALA A 1 187 ? -29.866 12.329  48.271 1   43.326  ? 176 ALA A CB   1 
ATOM   2611 H  H    . ALA A 1 187 ? -28.167 13.222  46.461 1   41.37   ? 176 ALA A H    1 
ATOM   2612 H  HA   . ALA A 1 187 ? -29.195 14.157  48.9   1   42.523  ? 176 ALA A HA   1 
ATOM   2613 H  HB1  . ALA A 1 187 ? -30.636 12.694  47.802 1   43.715  ? 176 ALA A HB1  1 
ATOM   2614 H  HB2  . ALA A 1 187 ? -29.513 11.576  47.769 1   43.715  ? 176 ALA A HB2  1 
ATOM   2615 H  HB3  . ALA A 1 187 ? -30.142 12.027  49.152 1   43.715  ? 176 ALA A HB3  1 
ATOM   2616 N  N    . ILE A 1 188 ? -27.558 13.21   50.476 1   39.87   ? 177 ILE A N    1 
ATOM   2617 C  CA   . ILE A 1 188 ? -26.48  12.824  51.363 1   39.447  ? 177 ILE A CA   1 
ATOM   2618 C  C    . ILE A 1 188 ? -27.145 12.046  52.468 1   35.677  ? 177 ILE A C    1 
ATOM   2619 O  O    . ILE A 1 188 ? -27.981 12.599  53.158 1   41.21   ? 177 ILE A O    1 
ATOM   2620 C  CB   . ILE A 1 188 ? -25.699 14.029  51.92  1   40.007  ? 177 ILE A CB   1 
ATOM   2621 C  CG1  . ILE A 1 188 ? -25.014 14.802  50.857 1   39.444  ? 177 ILE A CG1  1 
ATOM   2622 C  CG2  . ILE A 1 188 ? -24.677 13.561  52.947 1   43.372  ? 177 ILE A CG2  1 
ATOM   2623 C  CD1  . ILE A 1 188 ? -24.688 16.217  51.255 1   36.551  ? 177 ILE A CD1  1 
ATOM   2624 H  H    . ILE A 1 188 ? -28.227 13.734  50.812 1   39.896  ? 177 ILE A H    1 
ATOM   2625 H  HA   . ILE A 1 188 ? -25.863 12.243  50.884 1   38.856  ? 177 ILE A HA   1 
ATOM   2626 H  HB   . ILE A 1 188 ? -26.334 14.623  52.367 1   40.354  ? 177 ILE A HB   1 
ATOM   2627 H  HG12 . ILE A 1 188 ? -24.183 14.342  50.618 1   38.917  ? 177 ILE A HG12 1 
ATOM   2628 H  HG13 . ILE A 1 188 ? -25.584 14.822  50.062 1   38.903  ? 177 ILE A HG13 1 
ATOM   2629 H  HG21 . ILE A 1 188 ? -24.059 14.283  53.149 1   42.256  ? 177 ILE A HG21 1 
ATOM   2630 H  HG22 . ILE A 1 188 ? -24.182 12.804  52.592 1   42.322  ? 177 ILE A HG22 1 
ATOM   2631 H  HG23 . ILE A 1 188 ? -25.133 13.293  53.763 1   42.293  ? 177 ILE A HG23 1 
ATOM   2632 H  HD11 . ILE A 1 188 ? -25.5   16.668  51.553 1   37.422  ? 177 ILE A HD11 1 
ATOM   2633 H  HD12 . ILE A 1 188 ? -24.317 16.692  50.487 1   37.407  ? 177 ILE A HD12 1 
ATOM   2634 H  HD13 . ILE A 1 188 ? -24.035 16.215  51.98  1   37.452  ? 177 ILE A HD13 1 
ATOM   2635 N  N    . ILE A 1 189 ? -26.843 10.751  52.53  1   38.879  ? 178 ILE A N    1 
ATOM   2636 C  CA   . ILE A 1 189 ? -27.39  9.866   53.541 1   32.136  ? 178 ILE A CA   1 
ATOM   2637 C  C    . ILE A 1 189 ? -26.264 9.516   54.515 1   38.152  ? 178 ILE A C    1 
ATOM   2638 O  O    . ILE A 1 189 ? -25.178 9.071   54.137 1   39.481  ? 178 ILE A O    1 
ATOM   2639 C  CB   . ILE A 1 189 ? -27.912 8.621   52.849 1   42.116  ? 178 ILE A CB   1 
ATOM   2640 C  CG1  . ILE A 1 189 ? -28.977 8.958   51.791 1   48.912  ? 178 ILE A CG1  1 
ATOM   2641 C  CG2  . ILE A 1 189 ? -28.414 7.601   53.853 1   43.17   ? 178 ILE A CG2  1 
ATOM   2642 C  CD1  . ILE A 1 189 ? -29.268 7.777   50.901 1   52.05   ? 178 ILE A CD1  1 
ATOM   2643 H  H    . ILE A 1 189 ? -26.267 10.401  51.913 1   36.553  ? 178 ILE A H    1 
ATOM   2644 H  HA   . ILE A 1 189 ? -28.119 10.31   54.015 1   36.219  ? 178 ILE A HA   1 
ATOM   2645 H  HB   . ILE A 1 189 ? -27.156 8.218   52.379 1   41.373  ? 178 ILE A HB   1 
ATOM   2646 H  HG12 . ILE A 1 189 ? -29.802 9.234   52.24  1   47.967  ? 178 ILE A HG12 1 
ATOM   2647 H  HG13 . ILE A 1 189 ? -28.663 9.705   51.241 1   47.92   ? 178 ILE A HG13 1 
ATOM   2648 H  HG21 . ILE A 1 189 ? -28.842 6.864   53.386 1   42.946  ? 178 ILE A HG21 1 
ATOM   2649 H  HG22 . ILE A 1 189 ? -29.056 8.02    54.45  1   42.872  ? 178 ILE A HG22 1 
ATOM   2650 H  HG23 . ILE A 1 189 ? -27.668 7.258   54.374 1   42.851  ? 178 ILE A HG23 1 
ATOM   2651 H  HD11 . ILE A 1 189 ? -28.442 7.29    50.719 1   50.899  ? 178 ILE A HD11 1 
ATOM   2652 H  HD12 . ILE A 1 189 ? -29.647 8.093   50.06  1   50.92   ? 178 ILE A HD12 1 
ATOM   2653 H  HD13 . ILE A 1 189 ? -29.904 7.181   51.34  1   50.878  ? 178 ILE A HD13 1 
ATOM   2654 N  N    . ASP A 1 190 ? -26.498 9.795   55.78  1   36.907  ? 179 ASP A N    1 
ATOM   2655 C  CA   . ASP A 1 190 ? -25.485 9.7     56.809 1   35.205  ? 179 ASP A CA   1 
ATOM   2656 C  C    . ASP A 1 190 ? -25.882 8.598   57.755 1   34.846  ? 179 ASP A C    1 
ATOM   2657 O  O    . ASP A 1 190 ? -26.774 8.81    58.578 1   34.497  ? 179 ASP A O    1 
ATOM   2658 C  CB   . ASP A 1 190 ? -25.327 11.033  57.491 1   37.096  ? 179 ASP A CB   1 
ATOM   2659 C  CG   . ASP A 1 190 ? -24.312 11.098  58.636 1   49.542  ? 179 ASP A CG   1 
ATOM   2660 O  OD1  . ASP A 1 190 ? -24.003 10.02   59.276 1   43.277  ? 179 ASP A OD1  1 
ATOM   2661 O  OD2  . ASP A 1 190 ? -23.859 12.239  58.931 1   39.602  ? 179 ASP A OD2  1 
ATOM   2662 H  H    . ASP A 1 190 ? -27.339 10.057  56.025 1   36.762  ? 179 ASP A H    1 
ATOM   2663 H  HA   . ASP A 1 190 ? -24.63  9.465   56.39  1   35.772  ? 179 ASP A HA   1 
ATOM   2664 H  HB2  . ASP A 1 190 ? -25.046 11.681  56.813 1   39.174  ? 179 ASP A HB2  1 
ATOM   2665 H  HB3  . ASP A 1 190 ? -26.201 11.324  57.826 1   39.12   ? 179 ASP A HB3  1 
ATOM   2666 N  N    . TRP A 1 191 ? -25.206 7.439   57.63  1   31.776  ? 180 TRP A N    1 
ATOM   2667 C  CA   . TRP A 1 191 ? -25.485 6.328   58.532 1   31.21   ? 180 TRP A CA   1 
ATOM   2668 C  C    . TRP A 1 191 ? -24.373 6.061   59.56  1   31.046  ? 180 TRP A C    1 
ATOM   2669 O  O    . TRP A 1 191 ? -24.439 5.079   60.263 1   30.107  ? 180 TRP A O    1 
ATOM   2670 C  CB   . TRP A 1 191 ? -25.897 5.082   57.737 1   35.244  ? 180 TRP A CB   1 
ATOM   2671 C  CG   . TRP A 1 191 ? -24.809 4.318   57.036 1   35.823  ? 180 TRP A CG   1 
ATOM   2672 C  CD1  . TRP A 1 191 ? -23.558 3.957   57.459 1   32.891  ? 180 TRP A CD1  1 
ATOM   2673 C  CD2  . TRP A 1 191 ? -24.981 3.724   55.746 1   34.32   ? 180 TRP A CD2  1 
ATOM   2674 N  NE1  . TRP A 1 191 ? -22.894 3.257   56.484 1   36.808  ? 180 TRP A NE1  1 
ATOM   2675 C  CE2  . TRP A 1 191 ? -23.765 3.08    55.431 1   43.68   ? 180 TRP A CE2  1 
ATOM   2676 C  CE3  . TRP A 1 191 ? -26.04  3.708   54.839 1   32.984  ? 180 TRP A CE3  1 
ATOM   2677 C  CZ2  . TRP A 1 191 ? -23.616 2.376   54.243 1   39.699  ? 180 TRP A CZ2  1 
ATOM   2678 C  CZ3  . TRP A 1 191 ? -25.871 3.036   53.655 1   33.336  ? 180 TRP A CZ3  1 
ATOM   2679 C  CH2  . TRP A 1 191 ? -24.714 2.298   53.413 1   39.203  ? 180 TRP A CH2  1 
ATOM   2680 H  H    . TRP A 1 191 ? -24.57  7.34    56.981 1   32.401  ? 180 TRP A H    1 
ATOM   2681 H  HA   . TRP A 1 191 ? -26.287 6.589   59.057 1   32.049  ? 180 TRP A HA   1 
ATOM   2682 H  HB2  . TRP A 1 191 ? -26.358 4.471   58.35  1   34.412  ? 180 TRP A HB2  1 
ATOM   2683 H  HB3  . TRP A 1 191 ? -26.564 5.355   57.071 1   34.401  ? 180 TRP A HB3  1 
ATOM   2684 H  HD1  . TRP A 1 191 ? -23.161 4.231   58.266 1   34.422  ? 180 TRP A HD1  1 
ATOM   2685 H  HE1  . TRP A 1 191 ? -22.088 2.928   56.547 1   37.264  ? 180 TRP A HE1  1 
ATOM   2686 H  HE3  . TRP A 1 191 ? -26.851 4.143   55.038 1   33.502  ? 180 TRP A HE3  1 
ATOM   2687 H  HZ2  . TRP A 1 191 ? -22.819 1.913   54.047 1   40.282  ? 180 TRP A HZ2  1 
ATOM   2688 H  HZ3  . TRP A 1 191 ? -26.593 2.972   53.052 1   34.604  ? 180 TRP A HZ3  1 
ATOM   2689 H  HH2  . TRP A 1 191 ? -24.613 1.881   52.576 1   37.82   ? 180 TRP A HH2  1 
ATOM   2690 N  N    . ASP A 1 192 ? -23.43  6.987   59.742 1   33.064  ? 181 ASP A N    1 
ATOM   2691 C  CA   . ASP A 1 192 ? -22.633 7.033   60.956 1   34.291  ? 181 ASP A CA   1 
ATOM   2692 C  C    . ASP A 1 192 ? -23.633 7.104   62.085 1   33.782  ? 181 ASP A C    1 
ATOM   2693 O  O    . ASP A 1 192 ? -24.654 7.687   61.901 1   35.367  ? 181 ASP A O    1 
ATOM   2694 C  CB   . ASP A 1 192 ? -21.754 8.286   61.018 1   34.612  ? 181 ASP A CB   1 
ATOM   2695 C  CG   . ASP A 1 192 ? -20.823 8.516   62.206 1   29.392  ? 181 ASP A CG   1 
ATOM   2696 O  OD1  . ASP A 1 192 ? -21.336 8.72    63.336 1   30.999  ? 181 ASP A OD1  1 
ATOM   2697 O  OD2  . ASP A 1 192 ? -19.576 8.339   62.016 1   33.614  ? 181 ASP A OD2  1 
ATOM   2698 H  H    . ASP A 1 192 ? -23.272 7.606   59.088 1   32.856  ? 181 ASP A H    1 
ATOM   2699 H  HA   . ASP A 1 192 ? -22.099 6.21    61.029 1   33.991  ? 181 ASP A HA   1 
ATOM   2700 H  HB2  . ASP A 1 192 ? -21.196 8.289   60.212 1   33.292  ? 181 ASP A HB2  1 
ATOM   2701 H  HB3  . ASP A 1 192 ? -22.337 9.069   60.962 1   33.427  ? 181 ASP A HB3  1 
ATOM   2702 N  N    . VAL A 1 193 ? -23.361 6.474   63.22  1   33.102  ? 182 VAL A N    1 
ATOM   2703 C  CA   . VAL A 1 193 ? -24.329 6.428   64.299 1   37.084  ? 182 VAL A CA   1 
ATOM   2704 C  C    . VAL A 1 193 ? -24.592 7.785   64.95  1   36.151  ? 182 VAL A C    1 
ATOM   2705 O  O    . VAL A 1 193 ? -25.478 7.902   65.79  1   33.185  ? 182 VAL A O    1 
ATOM   2706 C  CB   . VAL A 1 193 ? -23.821 5.396   65.303 1   30.091  ? 182 VAL A CB   1 
ATOM   2707 C  CG1  . VAL A 1 193 ? -22.696 5.934   66.183 1   34.471  ? 182 VAL A CG1  1 
ATOM   2708 C  CG2  . VAL A 1 193 ? -24.915 4.818   66.167 1   30.595  ? 182 VAL A CG2  1 
ATOM   2709 H  H    . VAL A 1 193 ? -22.549 6.068   63.33  1   34.08   ? 182 VAL A H    1 
ATOM   2710 H  HA   . VAL A 1 193 ? -25.173 6.101   63.93  1   34.683  ? 182 VAL A HA   1 
ATOM   2711 H  HB   . VAL A 1 193 ? -23.447 4.649   64.78  1   32.197  ? 182 VAL A HB   1 
ATOM   2712 H  HG11 . VAL A 1 193 ? -23.075 6.413   66.94  1   33.079  ? 182 VAL A HG11 1 
ATOM   2713 H  HG12 . VAL A 1 193 ? -22.139 6.539   65.666 1   33.086  ? 182 VAL A HG12 1 
ATOM   2714 H  HG13 . VAL A 1 193 ? -22.155 5.196   66.507 1   33.06   ? 182 VAL A HG13 1 
ATOM   2715 H  HG21 . VAL A 1 193 ? -24.569 4.057   66.663 1   30.455  ? 182 VAL A HG21 1 
ATOM   2716 H  HG22 . VAL A 1 193 ? -25.654 4.529   65.605 1   30.463  ? 182 VAL A HG22 1 
ATOM   2717 H  HG23 . VAL A 1 193 ? -25.23  5.494   66.791 1   30.479  ? 182 VAL A HG23 1 
ATOM   2718 N  N    . HIS A 1 194 ? -23.755 8.768   64.692 1   34.144  ? 183 HIS A N    1 
ATOM   2719 C  CA   . HIS A 1 194 ? -23.905 10.07   65.318 1   31.043  ? 183 HIS A CA   1 
ATOM   2720 C  C    . HIS A 1 194 ? -24.628 11.014  64.362 1   30.708  ? 183 HIS A C    1 
ATOM   2721 O  O    . HIS A 1 194 ? -24.594 10.858  63.113 1   32.408  ? 183 HIS A O    1 
ATOM   2722 C  CB   . HIS A 1 194 ? -22.513 10.58   65.75  1   29.259  ? 183 HIS A CB   1 
ATOM   2723 C  CG   . HIS A 1 194 ? -21.766 9.606   66.642 1   34.757  ? 183 HIS A CG   1 
ATOM   2724 N  ND1  . HIS A 1 194 ? -20.661 8.816   66.314 1   25.029  ? 183 HIS A ND1  1 
ATOM   2725 C  CD2  . HIS A 1 194 ? -22.02  9.361   67.925 1   32.634  ? 183 HIS A CD2  1 
ATOM   2726 C  CE1  . HIS A 1 194 ? -20.325 8.119   67.382 1   36.81   ? 183 HIS A CE1  1 
ATOM   2727 N  NE2  . HIS A 1 194 ? -21.131 8.408   68.386 1   26.968  ? 183 HIS A NE2  1 
ATOM   2728 H  H    . HIS A 1 194 ? -23.055 8.633   64.121 1   33.834  ? 183 HIS A H    1 
ATOM   2729 H  HA   . HIS A 1 194 ? -24.461 9.969   66.129 1   31.262  ? 183 HIS A HA   1 
ATOM   2730 H  HB2  . HIS A 1 194 ? -21.976 10.753  64.946 1   30.852  ? 183 HIS A HB2  1 
ATOM   2731 H  HB3  . HIS A 1 194 ? -22.623 11.429  66.229 1   30.876  ? 183 HIS A HB3  1 
ATOM   2732 H  HD1  . HIS A 1 194 ? -20.259 8.807   65.538 0   24.62   ? 183 HIS A HD1  1 
ATOM   2733 H  HD2  . HIS A 1 194 ? -22.713 9.74    68.428 1   31.73   ? 183 HIS A HD2  1 
ATOM   2734 H  HE1  . HIS A 1 194 ? -19.612 7.505   67.413 1   31.276  ? 183 HIS A HE1  1 
ATOM   2735 H  HE2  . HIS A 1 194 ? -21.114 8.052   69.186 0   26.78   ? 183 HIS A HE2  1 
ATOM   2736 N  N    . HIS A 1 195 ? -25.175 12.104  64.901 1   35.059  ? 184 HIS A N    1 
ATOM   2737 C  CA   . HIS A 1 195 ? -25.888 13.035  64.043 1   33.759  ? 184 HIS A CA   1 
ATOM   2738 C  C    . HIS A 1 195 ? -24.937 13.842  63.169 1   37.518  ? 184 HIS A C    1 
ATOM   2739 O  O    . HIS A 1 195 ? -23.942 14.39   63.609 1   36.389  ? 184 HIS A O    1 
ATOM   2740 C  CB   . HIS A 1 195 ? -26.839 13.883  64.869 1   42.934  ? 184 HIS A CB   1 
ATOM   2741 C  CG   . HIS A 1 195 ? -27.453 14.953  64.049 1   42.042  ? 184 HIS A CG   1 
ATOM   2742 N  ND1  . HIS A 1 195 ? -27.295 16.289  64.34  1   37.024  ? 184 HIS A ND1  1 
ATOM   2743 C  CD2  . HIS A 1 195 ? -28.314 14.854  62.993 1   35.808  ? 184 HIS A CD2  1 
ATOM   2744 C  CE1  . HIS A 1 195 ? -27.994 16.979  63.453 1   38.485  ? 184 HIS A CE1  1 
ATOM   2745 N  NE2  . HIS A 1 195 ? -28.575 16.127  62.624 1   32.695  ? 184 HIS A NE2  1 
ATOM   2746 H  H    . HIS A 1 195 ? -25.107 12.27   65.797 1   33.763  ? 184 HIS A H    1 
ATOM   2747 H  HA   . HIS A 1 195 ? -26.455 12.49   63.446 1   36.268  ? 184 HIS A HA   1 
ATOM   2748 H  HB2  . HIS A 1 195 ? -27.547 13.308  65.233 1   40.435  ? 184 HIS A HB2  1 
ATOM   2749 H  HB3  . HIS A 1 195 ? -26.344 14.288  65.613 1   40.358  ? 184 HIS A HB3  1 
ATOM   2750 H  HD1  . HIS A 1 195 ? -26.823 16.636  65.011 0   36.93   ? 184 HIS A HD1  1 
ATOM   2751 H  HD2  . HIS A 1 195 ? -28.6   14.075  62.558 1   36.407  ? 184 HIS A HD2  1 
ATOM   2752 H  HE1  . HIS A 1 195 ? -28.041 17.919  63.403 1   36.763  ? 184 HIS A HE1  1 
ATOM   2753 H  HE2  . HIS A 1 195 ? -29.061 16.364  61.937 0   32.4    ? 184 HIS A HE2  1 
ATOM   2754 N  N    . GLY A 1 196 ? -25.253 13.899  61.874 1   41.11   ? 185 GLY A N    1 
ATOM   2755 C  CA   . GLY A 1 196 ? -24.501 14.696  60.935 1   32.513  ? 185 GLY A CA   1 
ATOM   2756 C  C    . GLY A 1 196 ? -24.862 16.175  61.033 1   37.953  ? 185 GLY A C    1 
ATOM   2757 O  O    . GLY A 1 196 ? -25.321 16.726  60.056 1   38.049  ? 185 GLY A O    1 
ATOM   2758 H  H    . GLY A 1 196 ? -25.978 13.434  61.569 1   38.078  ? 185 GLY A H    1 
ATOM   2759 H  HA2  . GLY A 1 196 ? -23.537 14.579  61.107 1   35.617  ? 185 GLY A HA2  1 
ATOM   2760 H  HA3  . GLY A 1 196 ? -24.686 14.375  60.022 1   35.636  ? 185 GLY A HA3  1 
ATOM   2761 N  N    . ASN A 1 197 ? -24.509 16.811  62.161 1   36.083  ? 186 ASN A N    1 
ATOM   2762 C  CA   . ASN A 1 197 ? -24.955 18.15   62.481 1   39.738  ? 186 ASN A CA   1 
ATOM   2763 C  C    . ASN A 1 197 ? -24.294 19.135  61.529 1   40.451  ? 186 ASN A C    1 
ATOM   2764 O  O    . ASN A 1 197 ? -24.813 20.225  61.329 1   36.158  ? 186 ASN A O    1 
ATOM   2765 C  CB   . ASN A 1 197 ? -24.693 18.559  63.939 1   34.09   ? 186 ASN A CB   1 
ATOM   2766 C  CG   . ASN A 1 197 ? -23.202 18.508  64.27  1   43.518  ? 186 ASN A CG   1 
ATOM   2767 O  OD1  . ASN A 1 197 ? -22.535 17.457  64.162 1   38.378  ? 186 ASN A OD1  1 
ATOM   2768 N  ND2  . ASN A 1 197 ? -22.614 19.652  64.544 1   33.458  ? 186 ASN A ND2  1 
ATOM   2769 H  H    . ASN A 1 197 ? -23.958 16.383  62.751 1   37.307  ? 186 ASN A H    1 
ATOM   2770 H  HA   . ASN A 1 197 ? -25.926 18.19   62.335 1   38.034  ? 186 ASN A HA   1 
ATOM   2771 H  HB2  . ASN A 1 197 ? -25.028 19.466  64.086 1   37.273  ? 186 ASN A HB2  1 
ATOM   2772 H  HB3  . ASN A 1 197 ? -25.177 17.955  64.537 1   37.299  ? 186 ASN A HB3  1 
ATOM   2773 H  HD21 . ASN A 1 197 ? -21.934 19.673  65.114 1   36.285  ? 186 ASN A HD21 1 
ATOM   2774 H  HD22 . ASN A 1 197 ? -22.895 20.4    64.158 1   36.279  ? 186 ASN A HD22 1 
ATOM   2775 N  N    . GLY A 1 198 ? -23.09  18.838  61.048 1   35.473  ? 187 GLY A N    1 
ATOM   2776 C  CA   . GLY A 1 198 ? -22.395 19.802  60.197 1   34.257  ? 187 GLY A CA   1 
ATOM   2777 C  C    . GLY A 1 198 ? -23.049 19.905  58.818 1   39.362  ? 187 GLY A C    1 
ATOM   2778 O  O    . GLY A 1 198 ? -23.38  20.985  58.301 1   39.818  ? 187 GLY A O    1 
ATOM   2779 H  H    . GLY A 1 198 ? -22.686 18.044  61.25  1   36.35   ? 187 GLY A H    1 
ATOM   2780 H  HA2  . GLY A 1 198 ? -22.402 20.686  60.633 1   35.683  ? 187 GLY A HA2  1 
ATOM   2781 H  HA3  . GLY A 1 198 ? -21.457 19.521  60.095 1   35.652  ? 187 GLY A HA3  1 
ATOM   2782 N  N    . THR A 1 199 ? -23.301 18.752  58.221 1   33.409  ? 188 THR A N    1 
ATOM   2783 C  CA   . THR A 1 199 ? -24.027 18.675  56.956 1   40.257  ? 188 THR A CA   1 
ATOM   2784 C  C    . THR A 1 199 ? -25.404 19.337  57.09  1   40.959  ? 188 THR A C    1 
ATOM   2785 O  O    . THR A 1 199 ? -25.838 20.033  56.216 1   45.243  ? 188 THR A O    1 
ATOM   2786 C  CB   . THR A 1 199 ? -24.184 17.2    56.576 1   40.271  ? 188 THR A CB   1 
ATOM   2787 O  OG1  . THR A 1 199 ? -22.948 16.551  56.838 1   40.808  ? 188 THR A OG1  1 
ATOM   2788 C  CG2  . THR A 1 199 ? -24.385 17.047  55.086 1   41.497  ? 188 THR A CG2  1 
ATOM   2789 H  H    . THR A 1 199 ? -23.007 17.976  58.606 1   36.237  ? 188 THR A H    1 
ATOM   2790 H  HA   . THR A 1 199 ? -23.508 19.135  56.261 1   38.969  ? 188 THR A HA   1 
ATOM   2791 H  HB   . THR A 1 199 ? -24.913 16.77   57.084 1   40.596  ? 188 THR A HB   1 
ATOM   2792 H  HG1  . THR A 1 199 ? -22.326 16.921  56.389 0   40.78   ? 188 THR A HG1  1 
ATOM   2793 H  HG21 . THR A 1 199 ? -24.485 16.106  54.867 1   41.125  ? 188 THR A HG21 1 
ATOM   2794 H  HG22 . THR A 1 199 ? -23.614 17.408  54.616 1   41.114  ? 188 THR A HG22 1 
ATOM   2795 H  HG23 . THR A 1 199 ? -25.184 17.529  54.814 1   41.125  ? 188 THR A HG23 1 
ATOM   2796 N  N    . GLN A 1 200 ? -26.143 19      58.14  1   36.594  ? 189 GLN A N    1 
ATOM   2797 C  CA   . GLN A 1 200 ? -27.457 19.544  58.359 1   40.182  ? 189 GLN A CA   1 
ATOM   2798 C  C    . GLN A 1 200 ? -27.422 21.067  58.353 1   42.665  ? 189 GLN A C    1 
ATOM   2799 O  O    . GLN A 1 200 ? -28.273 21.627  57.707 1   45.432  ? 189 GLN A O    1 
ATOM   2800 C  CB   . GLN A 1 200 ? -28.077 19.148  59.669 1   35.088  ? 189 GLN A CB   1 
ATOM   2801 C  CG   . GLN A 1 200 ? -29.375 19.875  60.027 1   40.985  ? 189 GLN A CG   1 
ATOM   2802 C  CD   . GLN A 1 200 ? -30.083 19.145  61.148 1   35.175  ? 189 GLN A CD   1 
ATOM   2803 O  OE1  . GLN A 1 200 ? -30.317 17.936  61.08  1   41.008  ? 189 GLN A OE1  1 
ATOM   2804 N  NE2  . GLN A 1 200 ? -30.328 19.823  62.251 1   43.761  ? 189 GLN A NE2  1 
ATOM   2805 H  H    . GLN A 1 200 ? -25.812 18.398  58.743 1   38.353  ? 189 GLN A H    1 
ATOM   2806 H  HA   . GLN A 1 200 ? -28.046 19.238  57.623 1   38.938  ? 189 GLN A HA   1 
ATOM   2807 H  HB2  . GLN A 1 200 ? -28.252 18.185  59.645 1   37.511  ? 189 GLN A HB2  1 
ATOM   2808 H  HB3  . GLN A 1 200 ? -27.422 19.309  60.381 1   37.507  ? 189 GLN A HB3  1 
ATOM   2809 H  HG2  . GLN A 1 200 ? -29.176 20.793  60.307 1   38.35   ? 189 GLN A HG2  1 
ATOM   2810 H  HG3  . GLN A 1 200 ? -29.96  19.914  59.241 1   38.26   ? 189 GLN A HG3  1 
ATOM   2811 H  HE21 . GLN A 1 200 ? -30.743 19.427  62.928 1   40.906  ? 189 GLN A HE21 1 
ATOM   2812 H  HE22 . GLN A 1 200 ? -30.08  20.672  62.322 1   40.887  ? 189 GLN A HE22 1 
ATOM   2813 N  N    . HIS A 1 201 ? -26.448 21.687  59.032 1   39.82   ? 190 HIS A N    1 
ATOM   2814 C  CA   . HIS A 1 201 ? -26.381 23.129  59.212 1   37.378  ? 190 HIS A CA   1 
ATOM   2815 C  C    . HIS A 1 201 ? -26.098 23.76   57.865 1   43.695  ? 190 HIS A C    1 
ATOM   2816 O  O    . HIS A 1 201 ? -26.687 24.764  57.484 1   42.964  ? 190 HIS A O    1 
ATOM   2817 C  CB   . HIS A 1 201 ? -25.336 23.565  60.238 1   37.06   ? 190 HIS A CB   1 
ATOM   2818 C  CG   . HIS A 1 201 ? -25.17  25.055  60.408 1   49.863  ? 190 HIS A CG   1 
ATOM   2819 N  ND1  . HIS A 1 201 ? -24.395 25.816  59.54  1   47.677  ? 190 HIS A ND1  1 
ATOM   2820 C  CD2  . HIS A 1 201 ? -25.57  25.878  61.371 1   50.433  ? 190 HIS A CD2  1 
ATOM   2821 C  CE1  . HIS A 1 201 ? -24.363 27.076  59.968 1   52.636  ? 190 HIS A CE1  1 
ATOM   2822 N  NE2  . HIS A 1 201 ? -25.051 27.133  61.083 1   51.604  ? 190 HIS A NE2  1 
ATOM   2823 H  H    . HIS A 1 201 ? -25.789 21.177  59.408 1   39.863  ? 190 HIS A H    1 
ATOM   2824 H  HA   . HIS A 1 201 ? -27.27  23.437  59.517 1   38.91   ? 190 HIS A HA   1 
ATOM   2825 H  HB2  . HIS A 1 201 ? -25.575 23.175  61.107 1   39.774  ? 190 HIS A HB2  1 
ATOM   2826 H  HB3  . HIS A 1 201 ? -24.47  23.18   59.981 1   39.774  ? 190 HIS A HB3  1 
ATOM   2827 H  HD1  . HIS A 1 201 ? -23.987 25.51   58.828 0   47.9    ? 190 HIS A HD1  1 
ATOM   2828 H  HD2  . HIS A 1 201 ? -26.091 25.658  62.118 1   50.473  ? 190 HIS A HD2  1 
ATOM   2829 H  HE1  . HIS A 1 201 ? -23.928 27.796  59.546 1   51.165  ? 190 HIS A HE1  1 
ATOM   2830 H  HE2  . HIS A 1 201 ? -25.171 27.849  61.575 0   51.93   ? 190 HIS A HE2  1 
ATOM   2831 N  N    . ILE A 1 202 ? -25.194 23.147  57.132 1   44.164  ? 191 ILE A N    1 
ATOM   2832 C  CA   . ILE A 1 202 ? -24.723 23.781  55.918 1   40.223  ? 191 ILE A CA   1 
ATOM   2833 C  C    . ILE A 1 202 ? -25.824 23.784  54.854 1   43.56   ? 191 ILE A C    1 
ATOM   2834 O  O    . ILE A 1 202 ? -25.908 24.751  54.111 1   40.216  ? 191 ILE A O    1 
ATOM   2835 C  CB   . ILE A 1 202 ? -23.443 23.12   55.409 1   35.159  ? 191 ILE A CB   1 
ATOM   2836 C  CG1  . ILE A 1 202 ? -22.262 23.399  56.354 1   40.909  ? 191 ILE A CG1  1 
ATOM   2837 C  CG2  . ILE A 1 202 ? -23.146 23.478  53.947 1   37.673  ? 191 ILE A CG2  1 
ATOM   2838 C  CD1  . ILE A 1 202 ? -21.127 22.388  56.189 1   42.043  ? 191 ILE A CD1  1 
ATOM   2839 H  H    . ILE A 1 202 ? -24.856 22.335  57.381 1   42.964  ? 191 ILE A H    1 
ATOM   2840 H  HA   . ILE A 1 202 ? -24.509 24.71   56.131 1   40.565  ? 191 ILE A HA   1 
ATOM   2841 H  HB   . ILE A 1 202 ? -23.598 22.155  55.435 1   37.655  ? 191 ILE A HB   1 
ATOM   2842 H  HG12 . ILE A 1 202 ? -21.918 24.298  56.177 1   39.782  ? 191 ILE A HG12 1 
ATOM   2843 H  HG13 . ILE A 1 202 ? -22.58  23.373  57.28  1   39.803  ? 191 ILE A HG13 1 
ATOM   2844 H  HG21 . ILE A 1 202 ? -22.23  23.237  53.732 1   37.01   ? 191 ILE A HG21 1 
ATOM   2845 H  HG22 . ILE A 1 202 ? -23.266 24.433  53.813 1   36.99   ? 191 ILE A HG22 1 
ATOM   2846 H  HG23 . ILE A 1 202 ? -23.75  22.991  53.361 1   36.981  ? 191 ILE A HG23 1 
ATOM   2847 H  HD11 . ILE A 1 202 ? -21.479 21.482  56.279 1   41.67   ? 191 ILE A HD11 1 
ATOM   2848 H  HD12 . ILE A 1 202 ? -20.451 22.542  56.876 1   41.692  ? 191 ILE A HD12 1 
ATOM   2849 H  HD13 . ILE A 1 202 ? -20.72  22.49   55.308 1   41.664  ? 191 ILE A HD13 1 
ATOM   2850 N  N    . TYR A 1 203 ? -26.651 22.739  54.79  1   43.152  ? 192 TYR A N    1 
ATOM   2851 C  CA   . TYR A 1 203 ? -27.696 22.673  53.779 1   39.015  ? 192 TYR A CA   1 
ATOM   2852 C  C    . TYR A 1 203 ? -29.101 22.941  54.328 1   42.112  ? 192 TYR A C    1 
ATOM   2853 O  O    . TYR A 1 203 ? -30.104 22.653  53.639 1   37.671  ? 192 TYR A O    1 
ATOM   2854 C  CB   . TYR A 1 203 ? -27.554 21.308  53.086 1   36.11   ? 192 TYR A CB   1 
ATOM   2855 C  CG   . TYR A 1 203 ? -26.288 21.218  52.269 1   39.168  ? 192 TYR A CG   1 
ATOM   2856 C  CD1  . TYR A 1 203 ? -25.996 22.143  51.268 1   36.255  ? 192 TYR A CD1  1 
ATOM   2857 C  CD2  . TYR A 1 203 ? -25.338 20.249  52.547 1   42.38   ? 192 TYR A CD2  1 
ATOM   2858 C  CE1  . TYR A 1 203 ? -24.836 22.064  50.512 1   41.528  ? 192 TYR A CE1  1 
ATOM   2859 C  CE2  . TYR A 1 203 ? -24.149 20.198  51.829 1   43.15   ? 192 TYR A CE2  1 
ATOM   2860 C  CZ   . TYR A 1 203 ? -23.886 21.102  50.826 1   43.731  ? 192 TYR A CZ   1 
ATOM   2861 O  OH   . TYR A 1 203 ? -22.729 20.934  50.138 1   40.735  ? 192 TYR A OH   1 
ATOM   2862 H  H    . TYR A 1 203 ? -26.562 22.049  55.383 1   42.242  ? 192 TYR A H    1 
ATOM   2863 H  HA   . TYR A 1 203 ? -27.506 23.373  53.102 1   39.777  ? 192 TYR A HA   1 
ATOM   2864 H  HB2  . TYR A 1 203 ? -27.552 20.602  53.77  1   37.639  ? 192 TYR A HB2  1 
ATOM   2865 H  HB3  . TYR A 1 203 ? -28.32  21.173  52.493 1   37.564  ? 192 TYR A HB3  1 
ATOM   2866 H  HD1  . TYR A 1 203 ? -26.634 22.806  51.056 1   38.195  ? 192 TYR A HD1  1 
ATOM   2867 H  HD2  . TYR A 1 203 ? -25.489 19.63   53.244 1   41.694  ? 192 TYR A HD2  1 
ATOM   2868 H  HE1  . TYR A 1 203 ? -24.667 22.693  49.832 1   40.78   ? 192 TYR A HE1  1 
ATOM   2869 H  HE2  . TYR A 1 203 ? -23.522 19.52   52.017 1   42.999  ? 192 TYR A HE2  1 
ATOM   2870 H  HH   . TYR A 1 203 ? -22.113 21.416  50.489 0   40.86   ? 192 TYR A HH   1 
ATOM   2871 N  N    . LEU A 1 204 ? -29.206 23.513  55.53  1   35.302  ? 193 LEU A N    1 
ATOM   2872 C  CA   . LEU A 1 204 ? -30.499 23.641  56.171 1   39.14   ? 193 LEU A CA   1 
ATOM   2873 C  C    . LEU A 1 204 ? -31.498 24.492  55.366 1   45.393  ? 193 LEU A C    1 
ATOM   2874 O  O    . LEU A 1 204 ? -32.687 24.319  55.503 1   47.588  ? 193 LEU A O    1 
ATOM   2875 C  CB   . LEU A 1 204 ? -30.336 24.293  57.533 1   38.647  ? 193 LEU A CB   1 
ATOM   2876 C  CG   . LEU A 1 204 ? -31.522 24.125  58.479 1   42.883  ? 193 LEU A CG   1 
ATOM   2877 C  CD1  . LEU A 1 204 ? -31.78  22.642  58.846 1   51.906  ? 193 LEU A CD1  1 
ATOM   2878 C  CD2  . LEU A 1 204 ? -31.359 24.968  59.752 1   43.091  ? 193 LEU A CD2  1 
ATOM   2879 H  H    . LEU A 1 204 ? -28.463 23.837  55.953 1   37.781  ? 193 LEU A H    1 
ATOM   2880 H  HA   . LEU A 1 204 ? -30.878 22.735  56.286 1   39.453  ? 193 LEU A HA   1 
ATOM   2881 H  HB2  . LEU A 1 204 ? -29.537 23.913  57.965 1   39.681  ? 193 LEU A HB2  1 
ATOM   2882 H  HB3  . LEU A 1 204 ? -30.177 25.256  57.399 1   39.715  ? 193 LEU A HB3  1 
ATOM   2883 H  HG   . LEU A 1 204 ? -32.33  24.458  58.013 1   43.636  ? 193 LEU A HG   1 
ATOM   2884 H  HD11 . LEU A 1 204 ? -32.162 22.179  58.083 1   49.002  ? 193 LEU A HD11 1 
ATOM   2885 H  HD12 . LEU A 1 204 ? -32.399 22.596  59.594 1   49.009  ? 193 LEU A HD12 1 
ATOM   2886 H  HD13 . LEU A 1 204 ? -30.942 22.218  59.095 1   49.066  ? 193 LEU A HD13 1 
ATOM   2887 H  HD21 . LEU A 1 204 ? -31.272 25.906  59.512 1   43.039  ? 193 LEU A HD21 1 
ATOM   2888 H  HD22 . LEU A 1 204 ? -30.564 24.682  60.232 1   43.039  ? 193 LEU A HD22 1 
ATOM   2889 H  HD23 . LEU A 1 204 ? -32.139 24.851  60.321 1   43.068  ? 193 LEU A HD23 1 
ATOM   2890 N  N    . GLN A 1 205 ? -31.035 25.477  54.619 1   47.789  ? 194 GLN A N    1 
ATOM   2891 C  CA   . GLN A 1 205 ? -31.933 26.423  53.978 1   59.508  ? 194 GLN A CA   1 
ATOM   2892 C  C    . GLN A 1 205 ? -31.961 26.121  52.488 1   60.047  ? 194 GLN A C    1 
ATOM   2893 O  O    . GLN A 1 205 ? -32.232 27.016  51.701 1   53.304  ? 194 GLN A O    1 
ATOM   2894 C  CB   . GLN A 1 205 ? -31.479 27.882  54.107 1   55.204  ? 194 GLN A CB   1 
ATOM   2895 C  CG   . GLN A 1 205 ? -31.176 28.342  55.533 1   65.796  ? 194 GLN A CG   1 
ATOM   2896 C  CD   . GLN A 1 205 ? -31.129 29.847  55.677 1   74.764  ? 194 GLN A CD   1 
ATOM   2897 O  OE1  . GLN A 1 205 ? -30.087 30.5    55.544 1   77.891  ? 194 GLN A OE1  1 
ATOM   2898 N  NE2  . GLN A 1 205 ? -32.295 30.422  55.905 1   78.189  ? 194 GLN A NE2  1 
ATOM   2899 H  H    . GLN A 1 205 ? -30.134 25.577  54.504 1   49.371  ? 194 GLN A H    1 
ATOM   2900 H  HA   . GLN A 1 205 ? -32.841 26.317  54.352 1   56.12   ? 194 GLN A HA   1 
ATOM   2901 H  HB2  . GLN A 1 205 ? -30.674 28.007  53.561 1   58.437  ? 194 GLN A HB2  1 
ATOM   2902 H  HB3  . GLN A 1 205 ? -32.179 28.458  53.735 1   58.491  ? 194 GLN A HB3  1 
ATOM   2903 H  HG2  . GLN A 1 205 ? -31.862 27.989  56.138 1   65.195  ? 194 GLN A HG2  1 
ATOM   2904 H  HG3  . GLN A 1 205 ? -30.312 27.972  55.814 1   65.137  ? 194 GLN A HG3  1 
ATOM   2905 H  HE21 . GLN A 1 205 ? -32.33  31.187  56.352 1   77.097  ? 194 GLN A HE21 1 
ATOM   2906 H  HE22 . GLN A 1 205 ? -33.042 30.044  55.611 1   77.029  ? 194 GLN A HE22 1 
ATOM   2907 N  N    . ARG A 1 206 ? -31.61  24.891  52.097 1   44.56   ? 195 ARG A N    1 
ATOM   2908 C  CA   . ARG A 1 206 ? -31.338 24.64   50.685 1   51.257  ? 195 ARG A CA   1 
ATOM   2909 C  C    . ARG A 1 206 ? -32.17  23.465  50.217 1   49.61   ? 195 ARG A C    1 
ATOM   2910 O  O    . ARG A 1 206 ? -32.376 22.525  50.961 1   59.479  ? 195 ARG A O    1 
ATOM   2911 C  CB   . ARG A 1 206 ? -29.85  24.461  50.377 1   57.549  ? 195 ARG A CB   1 
ATOM   2912 C  CG   . ARG A 1 206 ? -29.222 25.807  50.038 1   56.72   ? 195 ARG A CG   1 
ATOM   2913 C  CD   . ARG A 1 206 ? -27.726 25.762  49.914 1   47.291  ? 195 ARG A CD   1 
ATOM   2914 N  NE   . ARG A 1 206 ? -27.353 24.972  48.743 1   59.211  ? 195 ARG A NE   1 
ATOM   2915 C  CZ   . ARG A 1 206 ? -26.092 24.821  48.329 1   51.144  ? 195 ARG A CZ   1 
ATOM   2916 N  NH1  . ARG A 1 206 ? -25.123 25.393  48.992 1   43.39   ? 195 ARG A NH1  1 
ATOM   2917 N  NH2  . ARG A 1 206 ? -25.804 24.089  47.28  1   46.599  ? 195 ARG A NH2  1 
ATOM   2918 H  H    . ARG A 1 206 ? -31.553 24.205  52.696 1   49.443  ? 195 ARG A H    1 
ATOM   2919 H  HA   . ARG A 1 206 ? -31.639 25.434  50.174 1   50.835  ? 195 ARG A HA   1 
ATOM   2920 H  HB2  . ARG A 1 206 ? -29.396 24.076  51.157 1   55.861  ? 195 ARG A HB2  1 
ATOM   2921 H  HB3  . ARG A 1 206 ? -29.739 23.847  49.621 1   55.781  ? 195 ARG A HB3  1 
ATOM   2922 H  HG2  . ARG A 1 206 ? -29.599 26.131  49.191 1   54.53   ? 195 ARG A HG2  1 
ATOM   2923 H  HG3  . ARG A 1 206 ? -29.462 26.455  50.735 1   54.551  ? 195 ARG A HG3  1 
ATOM   2924 H  HD2  . ARG A 1 206 ? -27.373 26.671  49.821 1   51.922  ? 195 ARG A HD2  1 
ATOM   2925 H  HD3  . ARG A 1 206 ? -27.337 25.36   50.717 1   51.959  ? 195 ARG A HD3  1 
ATOM   2926 H  HE   . ARG A 1 206 ? -27.982 24.583  48.285 1   54.242  ? 195 ARG A HE   1 
ATOM   2927 H  HH11 . ARG A 1 206 ? -24.927 25.117  49.809 1   45.653  ? 195 ARG A HH11 1 
ATOM   2928 H  HH12 . ARG A 1 206 ? -24.666 26.052  48.62  1   45.646  ? 195 ARG A HH12 1 
ATOM   2929 H  HH21 . ARG A 1 206 ? -26.333 23.418  47.053 1   48.032  ? 195 ARG A HH21 1 
ATOM   2930 H  HH22 . ARG A 1 206 ? -25.081 24.269  46.804 1   47.937  ? 195 ARG A HH22 1 
ATOM   2931 N  N    . ASP A 1 207 ? -32.699 23.557  48.998 1   57.265  ? 196 ASP A N    1 
ATOM   2932 C  CA   . ASP A 1 207 ? -33.627 22.541  48.529 1   51.746  ? 196 ASP A CA   1 
ATOM   2933 C  C    . ASP A 1 207 ? -32.934 21.728  47.457 1   45.2    ? 196 ASP A C    1 
ATOM   2934 O  O    . ASP A 1 207 ? -33.545 20.771  46.979 1   48.624  ? 196 ASP A O    1 
ATOM   2935 C  CB   . ASP A 1 207 ? -34.963 23.115  48.064 1   56.039  ? 196 ASP A CB   1 
ATOM   2936 C  CG   . ASP A 1 207 ? -34.936 24.153  46.942 1   60.542  ? 196 ASP A CG   1 
ATOM   2937 O  OD1  . ASP A 1 207 ? -33.893 24.307  46.256 1   55.718  ? 196 ASP A OD1  1 
ATOM   2938 O  OD2  . ASP A 1 207 ? -35.971 24.831  46.768 1   74.579  ? 196 ASP A OD2  1 
ATOM   2939 H  H    . ASP A 1 207 ? -32.5   24.269  48.46  1   53.938  ? 196 ASP A H    1 
ATOM   2940 H  HA   . ASP A 1 207 ? -33.831 21.94   49.28  1   52.262  ? 196 ASP A HA   1 
ATOM   2941 H  HB2  . ASP A 1 207 ? -35.53  22.372  47.768 1   55.968  ? 196 ASP A HB2  1 
ATOM   2942 H  HB3  . ASP A 1 207 ? -35.398 23.526  48.837 1   55.983  ? 196 ASP A HB3  1 
ATOM   2943 N  N    . ASP A 1 208 ? -31.697 22.142  47.078 1   44.41   ? 197 ASP A N    1 
ATOM   2944 C  CA   . ASP A 1 208 ? -30.926 21.416  46.075 1   54.66   ? 197 ASP A CA   1 
ATOM   2945 C  C    . ASP A 1 208 ? -30.096 20.263  46.685 1   51.867  ? 197 ASP A C    1 
ATOM   2946 O  O    . ASP A 1 208 ? -29.469 19.473  45.965 1   40.582  ? 197 ASP A O    1 
ATOM   2947 C  CB   . ASP A 1 208 ? -30.099 22.382  45.255 1   52.211  ? 197 ASP A CB   1 
ATOM   2948 C  CG   . ASP A 1 208 ? -29.061 23.155  46.054 1   54.766  ? 197 ASP A CG   1 
ATOM   2949 O  OD1  . ASP A 1 208 ? -29.399 23.666  47.133 1   47.747  ? 197 ASP A OD1  1 
ATOM   2950 O  OD2  . ASP A 1 208 ? -27.917 23.26   45.559 1   49.307  ? 197 ASP A OD2  1 
ATOM   2951 H  H    . ASP A 1 208 ? -31.33  22.887  47.457 1   47.008  ? 197 ASP A H    1 
ATOM   2952 H  HA   . ASP A 1 208 ? -31.563 21.017  45.44  1   51.502  ? 197 ASP A HA   1 
ATOM   2953 H  HB2  . ASP A 1 208 ? -29.638 21.883  44.549 1   53.316  ? 197 ASP A HB2  1 
ATOM   2954 H  HB3  . ASP A 1 208 ? -30.7   23.028  44.826 1   53.337  ? 197 ASP A HB3  1 
ATOM   2955 N  N    . VAL A 1 209 ? -30.164 20.1    48.013 1   45.416  ? 198 VAL A N    1 
ATOM   2956 C  CA   . VAL A 1 209 ? -29.556 18.962  48.686 1   42.689  ? 198 VAL A CA   1 
ATOM   2957 C  C    . VAL A 1 209 ? -30.505 18.452  49.765 1   37.747  ? 198 VAL A C    1 
ATOM   2958 O  O    . VAL A 1 209 ? -30.908 19.225  50.644 1   40.641  ? 198 VAL A O    1 
ATOM   2959 C  CB   . VAL A 1 209 ? -28.216 19.404  49.325 1   46.25   ? 198 VAL A CB   1 
ATOM   2960 C  CG1  . VAL A 1 209 ? -27.572 18.273  50.132 1   44.792  ? 198 VAL A CG1  1 
ATOM   2961 C  CG2  . VAL A 1 209 ? -27.269 19.993  48.299 1   40.843  ? 198 VAL A CG2  1 
ATOM   2962 H  H    . VAL A 1 209 ? -30.591 20.728  48.521 1   46.197  ? 198 VAL A H    1 
ATOM   2963 H  HA   . VAL A 1 209 ? -29.388 18.256  48.038 1   42.793  ? 198 VAL A HA   1 
ATOM   2964 H  HB   . VAL A 1 209 ? -28.432 20.124  49.963 1   44.248  ? 198 VAL A HB   1 
ATOM   2965 H  HG11 . VAL A 1 209 ? -27.576 17.455  49.605 1   45.202  ? 198 VAL A HG11 1 
ATOM   2966 H  HG12 . VAL A 1 209 ? -28.072 18.131  50.952 1   45.176  ? 198 VAL A HG12 1 
ATOM   2967 H  HG13 . VAL A 1 209 ? -26.655 18.511  50.351 1   45.186  ? 198 VAL A HG13 1 
ATOM   2968 H  HG21 . VAL A 1 209 ? -26.366 20.008  48.659 1   42.429  ? 198 VAL A HG21 1 
ATOM   2969 H  HG22 . VAL A 1 209 ? -27.545 20.901  48.086 1   42.416  ? 198 VAL A HG22 1 
ATOM   2970 H  HG23 . VAL A 1 209 ? -27.286 19.453  47.492 1   42.463  ? 198 VAL A HG23 1 
ATOM   2971 N  N    . LEU A 1 210 ? -30.751 17.141  49.72  1   39.216  ? 199 LEU A N    1 
ATOM   2972 C  CA   . LEU A 1 210 ? -31.477 16.404  50.737 1   40.811  ? 199 LEU A CA   1 
ATOM   2973 C  C    . LEU A 1 210 ? -30.459 15.757  51.698 1   44.633  ? 199 LEU A C    1 
ATOM   2974 O  O    . LEU A 1 210 ? -29.573 15.033  51.27  1   41.896  ? 199 LEU A O    1 
ATOM   2975 C  CB   . LEU A 1 210 ? -32.318 15.357  49.987 1   37.626  ? 199 LEU A CB   1 
ATOM   2976 C  CG   . LEU A 1 210 ? -33.131 14.407  50.854 1   39.293  ? 199 LEU A CG   1 
ATOM   2977 C  CD1  . LEU A 1 210 ? -34.086 15.216  51.628 1   39.961  ? 199 LEU A CD1  1 
ATOM   2978 C  CD2  . LEU A 1 210 ? -33.829 13.26   50.169 1   43.077  ? 199 LEU A CD2  1 
ATOM   2979 H  H    . LEU A 1 210 ? -30.439 16.674  48.999 1   39.257  ? 199 LEU A H    1 
ATOM   2980 H  HA   . LEU A 1 210 ? -32.068 17.024  51.23  1   40.598  ? 199 LEU A HA   1 
ATOM   2981 H  HB2  . LEU A 1 210 ? -32.933 15.832  49.383 1   38.721  ? 199 LEU A HB2  1 
ATOM   2982 H  HB3  . LEU A 1 210 ? -31.711 14.82   49.427 1   38.713  ? 199 LEU A HB3  1 
ATOM   2983 H  HG   . LEU A 1 210 ? -32.507 14.002  51.509 1   39.847  ? 199 LEU A HG   1 
ATOM   2984 H  HD11 . LEU A 1 210 ? -33.612 15.707  52.32  1   39.798  ? 199 LEU A HD11 1 
ATOM   2985 H  HD12 . LEU A 1 210 ? -34.745 14.635  52.043 1   39.796  ? 199 LEU A HD12 1 
ATOM   2986 H  HD13 . LEU A 1 210 ? -34.537 15.844  51.038 1   39.753  ? 199 LEU A HD13 1 
ATOM   2987 H  HD21 . LEU A 1 210 ? -33.167 12.636  49.826 1   41.916  ? 199 LEU A HD21 1 
ATOM   2988 H  HD22 . LEU A 1 210 ? -34.365 13.599  49.433 1   41.916  ? 199 LEU A HD22 1 
ATOM   2989 H  HD23 . LEU A 1 210 ? -34.406 12.802  50.803 1   41.921  ? 199 LEU A HD23 1 
ATOM   2990 N  N    . THR A 1 211 ? -30.524 16.108  52.983 1   39.939  ? 200 THR A N    1 
ATOM   2991 C  CA   . THR A 1 211 ? -29.625 15.612  54.002 1   39.652  ? 200 THR A CA   1 
ATOM   2992 C  C    . THR A 1 211 ? -30.493 14.719  54.837 1   40.787  ? 200 THR A C    1 
ATOM   2993 O  O    . THR A 1 211 ? -31.541 15.138  55.287 1   43.721  ? 200 THR A O    1 
ATOM   2994 C  CB   . THR A 1 211 ? -29.008 16.727  54.83  1   45.879  ? 200 THR A CB   1 
ATOM   2995 O  OG1  . THR A 1 211 ? -30.023 17.682  55.153 1   64.222  ? 200 THR A OG1  1 
ATOM   2996 C  CG2  . THR A 1 211 ? -28.08  17.551  53.966 1   46.695  ? 200 THR A CG2  1 
ATOM   2997 H  H    . THR A 1 211 ? -31.179 16.691  53.239 1   40.99   ? 200 THR A H    1 
ATOM   2998 H  HA   . THR A 1 211 ? -28.911 15.087  53.581 1   40.978  ? 200 THR A HA   1 
ATOM   2999 H  HB   . THR A 1 211 ? -28.565 16.393  55.647 1   47.935  ? 200 THR A HB   1 
ATOM   3000 H  HG1  . THR A 1 211 ? -30.354 17.996  54.432 0   64.21   ? 200 THR A HG1  1 
ATOM   3001 H  HG21 . THR A 1 211 ? -27.776 18.328  54.465 1   46.484  ? 200 THR A HG21 1 
ATOM   3002 H  HG22 . THR A 1 211 ? -28.551 17.842  53.169 1   46.457  ? 200 THR A HG22 1 
ATOM   3003 H  HG23 . THR A 1 211 ? -27.313 17.012  53.709 1   46.459  ? 200 THR A HG23 1 
ATOM   3004 N  N    . ILE A 1 212 ? -30.106 13.453  54.879 1   37.379  ? 201 ILE A N    1 
ATOM   3005 C  CA   . ILE A 1 212 ? -30.725 12.496  55.766 1   39.252  ? 201 ILE A CA   1 
ATOM   3006 C  C    . ILE A 1 212 ? -29.691 11.965  56.764 1   39.576  ? 201 ILE A C    1 
ATOM   3007 O  O    . ILE A 1 212 ? -28.585 11.601  56.359 1   42.691  ? 201 ILE A O    1 
ATOM   3008 C  CB   . ILE A 1 212 ? -31.304 11.388  54.874 1   41.337  ? 201 ILE A CB   1 
ATOM   3009 C  CG1  . ILE A 1 212 ? -32.258 11.995  53.812 1   46.811  ? 201 ILE A CG1  1 
ATOM   3010 C  CG2  . ILE A 1 212 ? -32.023 10.351  55.734 1   38.017  ? 201 ILE A CG2  1 
ATOM   3011 C  CD1  . ILE A 1 212 ? -32.942 10.943  52.991 1   47.013  ? 201 ILE A CD1  1 
ATOM   3012 H  H    . ILE A 1 212 ? -29.43  13.17   54.333 1   38.619  ? 201 ILE A H    1 
ATOM   3013 H  HA   . ILE A 1 212 ? -31.452 12.927  56.25  1   39.336  ? 201 ILE A HA   1 
ATOM   3014 H  HB   . ILE A 1 212 ? -30.565 10.948  54.409 1   41.237  ? 201 ILE A HB   1 
ATOM   3015 H  HG12 . ILE A 1 212 ? -32.935 12.539  54.263 1   45.546  ? 201 ILE A HG12 1 
ATOM   3016 H  HG13 . ILE A 1 212 ? -31.746 12.579  53.217 1   45.482  ? 201 ILE A HG13 1 
ATOM   3017 H  HG21 . ILE A 1 212 ? -32.272 9.589   55.186 1   39.055  ? 201 ILE A HG21 1 
ATOM   3018 H  HG22 . ILE A 1 212 ? -32.822 10.746  56.12  1   38.987  ? 201 ILE A HG22 1 
ATOM   3019 H  HG23 . ILE A 1 212 ? -31.435 10.052  56.448 1   38.989  ? 201 ILE A HG23 1 
ATOM   3020 H  HD11 . ILE A 1 212 ? -32.308 10.232  52.777 1   46.901  ? 201 ILE A HD11 1 
ATOM   3021 H  HD12 . ILE A 1 212 ? -33.274 11.338  52.163 1   46.872  ? 201 ILE A HD12 1 
ATOM   3022 H  HD13 . ILE A 1 212 ? -33.691 10.568  53.492 1   46.863  ? 201 ILE A HD13 1 
ATOM   3023 N  N    . SER A 1 213 ? -30.05  11.918  58.057 1   38.629  ? 202 SER A N    1 
ATOM   3024 C  CA   . SER A 1 213 ? -29.199 11.345  59.08  1   36.215  ? 202 SER A CA   1 
ATOM   3025 C  C    . SER A 1 213 ? -29.981 10.316  59.849 1   36.731  ? 202 SER A C    1 
ATOM   3026 O  O    . SER A 1 213 ? -31.067 10.657  60.29  1   40.502  ? 202 SER A O    1 
ATOM   3027 C  CB   . SER A 1 213 ? -28.668 12.413  59.995 1   47.528  ? 202 SER A CB   1 
ATOM   3028 O  OG   . SER A 1 213 ? -27.912 11.786  61.019 1   39.922  ? 202 SER A OG   1 
ATOM   3029 H  H    . SER A 1 213 ? -30.86  12.259  58.305 1   38.293  ? 202 SER A H    1 
ATOM   3030 H  HA   . SER A 1 213 ? -28.436 10.896  58.64  1   38.63   ? 202 SER A HA   1 
ATOM   3031 H  HB2  . SER A 1 213 ? -28.101 13.026  59.492 1   42.858  ? 202 SER A HB2  1 
ATOM   3032 H  HB3  . SER A 1 213 ? -29.409 12.912  60.386 1   42.869  ? 202 SER A HB3  1 
ATOM   3033 H  HG   . SER A 1 213 ? -27.626 12.405  61.533 0   39.81   ? 202 SER A HG   1 
ATOM   3034 N  N    . LEU A 1 214 ? -29.49  9.062   59.876 1   35.878  ? 203 LEU A N    1 
ATOM   3035 C  CA   . LEU A 1 214 ? -29.886 8.053   60.842 1   30.219  ? 203 LEU A CA   1 
ATOM   3036 C  C    . LEU A 1 214 ? -28.867 8.108   61.961 1   34.031  ? 203 LEU A C    1 
ATOM   3037 O  O    . LEU A 1 214 ? -27.669 8.236   61.685 1   38.756  ? 203 LEU A O    1 
ATOM   3038 C  CB   . LEU A 1 214 ? -29.876 6.65    60.255 1   34.45   ? 203 LEU A CB   1 
ATOM   3039 C  CG   . LEU A 1 214 ? -30.802 6.372   59.071 1   43.923  ? 203 LEU A CG   1 
ATOM   3040 C  CD1  . LEU A 1 214 ? -30.068 6.206   57.797 1   52.089  ? 203 LEU A CD1  1 
ATOM   3041 C  CD2  . LEU A 1 214 ? -31.578 5.138   59.357 1   49.426  ? 203 LEU A CD2  1 
ATOM   3042 H  H    . LEU A 1 214 ? -28.886 8.822   59.234 1   34.744  ? 203 LEU A H    1 
ATOM   3043 H  HA   . LEU A 1 214 ? -30.788 8.268   61.193 1   32.761  ? 203 LEU A HA   1 
ATOM   3044 H  HB2  . LEU A 1 214 ? -28.953 6.444   59.977 1   35.529  ? 203 LEU A HB2  1 
ATOM   3045 H  HB3  . LEU A 1 214 ? -30.098 6.018   60.977 1   35.573  ? 203 LEU A HB3  1 
ATOM   3046 H  HG   . LEU A 1 214 ? -31.433 7.132   58.978 1   44.234  ? 203 LEU A HG   1 
ATOM   3047 H  HD11 . LEU A 1 214 ? -29.552 7.009   57.613 1   49.437  ? 203 LEU A HD11 1 
ATOM   3048 H  HD12 . LEU A 1 214 ? -30.7   6.056   57.075 1   49.428  ? 203 LEU A HD12 1 
ATOM   3049 H  HD13 . LEU A 1 214 ? -29.468 5.445   57.865 1   49.352  ? 203 LEU A HD13 1 
ATOM   3050 H  HD21 . LEU A 1 214 ? -32.126 5.274   60.148 1   47.582  ? 203 LEU A HD21 1 
ATOM   3051 H  HD22 . LEU A 1 214 ? -30.967 4.398   59.51  1   47.584  ? 203 LEU A HD22 1 
ATOM   3052 H  HD23 . LEU A 1 214 ? -32.152 4.932   58.6   1   47.686  ? 203 LEU A HD23 1 
ATOM   3053 N  N    . HIS A 1 215 ? -29.335 8.106   63.198 1   32.12   ? 204 HIS A N    1 
ATOM   3054 C  CA   . HIS A 1 215 ? -28.416 8.265   64.293 1   31.343  ? 204 HIS A CA   1 
ATOM   3055 C  C    . HIS A 1 215 ? -29.067 7.776   65.557 1   35.891  ? 204 HIS A C    1 
ATOM   3056 O  O    . HIS A 1 215 ? -30.28  7.619   65.615 1   30.61   ? 204 HIS A O    1 
ATOM   3057 C  CB   . HIS A 1 215 ? -27.927 9.696   64.434 1   35.184  ? 204 HIS A CB   1 
ATOM   3058 C  CG   . HIS A 1 215 ? -28.994 10.687  64.535 1   39.536  ? 204 HIS A CG   1 
ATOM   3059 N  ND1  . HIS A 1 215 ? -29.404 11.374  63.421 1   34.615  ? 204 HIS A ND1  1 
ATOM   3060 C  CD2  . HIS A 1 215 ? -29.724 11.125  65.59  1   37.698  ? 204 HIS A CD2  1 
ATOM   3061 C  CE1  . HIS A 1 215 ? -30.33  12.209  63.815 1   37.224  ? 204 HIS A CE1  1 
ATOM   3062 N  NE2  . HIS A 1 215 ? -30.559 12.074  65.113 1   34.324  ? 204 HIS A NE2  1 
ATOM   3063 H  H    . HIS A 1 215 ? -30.228 8.006   63.364 1   32.397  ? 204 HIS A H    1 
ATOM   3064 H  HA   . HIS A 1 215 ? -27.632 7.688   64.114 1   33.021  ? 204 HIS A HA   1 
ATOM   3065 H  HB2  . HIS A 1 215 ? -27.364 9.756   65.236 1   35.235  ? 204 HIS A HB2  1 
ATOM   3066 H  HB3  . HIS A 1 215 ? -27.365 9.914   63.668 1   35.257  ? 204 HIS A HB3  1 
ATOM   3067 H  HD1  . HIS A 1 215 ? -29.1   11.276  62.602 0   34.57   ? 204 HIS A HD1  1 
ATOM   3068 H  HD2  . HIS A 1 215 ? -29.663 10.836  66.479 1   37.267  ? 204 HIS A HD2  1 
ATOM   3069 H  HE1  . HIS A 1 215 ? -30.789 12.795  63.239 1   35.933  ? 204 HIS A HE1  1 
ATOM   3070 H  HE2  . HIS A 1 215 ? -31.161 12.522  65.577 0   34.33   ? 204 HIS A HE2  1 
ATOM   3071 N  N    . GLN A 1 216 ? -28.228 7.487   66.537 1   31.085  ? 205 GLN A N    1 
ATOM   3072 C  CA   . GLN A 1 216 ? -28.717 7.141   67.851 1   30.33   ? 205 GLN A CA   1 
ATOM   3073 C  C    . GLN A 1 216 ? -29.245 8.389   68.548 1   33.838  ? 205 GLN A C    1 
ATOM   3074 O  O    . GLN A 1 216 ? -28.585 9.413   68.611 1   31.985  ? 205 GLN A O    1 
ATOM   3075 C  CB   . GLN A 1 216 ? -27.645 6.469   68.666 1   29.587  ? 205 GLN A CB   1 
ATOM   3076 C  CG   . GLN A 1 216 ? -28.092 6.124   70.085 1   34.687  ? 205 GLN A CG   1 
ATOM   3077 C  CD   . GLN A 1 216 ? -26.934 5.479   70.814 1   38.919  ? 205 GLN A CD   1 
ATOM   3078 O  OE1  . GLN A 1 216 ? -26.315 4.555   70.28  1   37.447  ? 205 GLN A OE1  1 
ATOM   3079 N  NE2  . GLN A 1 216 ? -26.631 5.954   72.008 1   37.3    ? 205 GLN A NE2  1 
ATOM   3080 H  H    . GLN A 1 216 ? -27.326 7.506   66.387 1   31.977  ? 205 GLN A H    1 
ATOM   3081 H  HA   . GLN A 1 216 ? -29.462 6.499   67.742 1   31.087  ? 205 GLN A HA   1 
ATOM   3082 H  HB2  . GLN A 1 216 ? -27.363 5.651   68.208 1   30.959  ? 205 GLN A HB2  1 
ATOM   3083 H  HB3  . GLN A 1 216 ? -26.869 7.065   68.714 1   30.907  ? 205 GLN A HB3  1 
ATOM   3084 H  HG2  . GLN A 1 216 ? -28.367 6.938   70.558 1   34.393  ? 205 GLN A HG2  1 
ATOM   3085 H  HG3  . GLN A 1 216 ? -28.855 5.509   70.058 1   34.358  ? 205 GLN A HG3  1 
ATOM   3086 H  HE21 . GLN A 1 216 ? -25.804 5.868   72.32  1   37.778  ? 205 GLN A HE21 1 
ATOM   3087 H  HE22 . GLN A 1 216 ? -27.252 6.357   72.498 1   37.738  ? 205 GLN A HE22 1 
ATOM   3088 N  N    . ASP A 1 217 ? -30.512 8.295   68.965 1   38.957  ? 206 ASP A N    1 
ATOM   3089 C  CA   . ASP A 1 217 ? -31.206 9.308   69.707 1   36.251  ? 206 ASP A CA   1 
ATOM   3090 C  C    . ASP A 1 217 ? -30.335 9.736   70.885 1   33.111  ? 206 ASP A C    1 
ATOM   3091 O  O    . ASP A 1 217 ? -30.039 8.928   71.777 1   33.676  ? 206 ASP A O    1 
ATOM   3092 C  CB   . ASP A 1 217 ? -32.53  8.738   70.233 1   39.702  ? 206 ASP A CB   1 
ATOM   3093 C  CG   . ASP A 1 217 ? -33.456 9.735   70.935 1   40.976  ? 206 ASP A CG   1 
ATOM   3094 O  OD1  . ASP A 1 217 ? -32.992 10.899  71.124 1   48.899  ? 206 ASP A OD1  1 
ATOM   3095 O  OD2  . ASP A 1 217 ? -34.615 9.332   71.327 1   46.318  ? 206 ASP A OD2  1 
ATOM   3096 H  H    . ASP A 1 217 ? -30.97  7.531   68.762 1   36.977  ? 206 ASP A H    1 
ATOM   3097 H  HA   . ASP A 1 217 ? -31.376 10.078  69.118 1   36.742  ? 206 ASP A HA   1 
ATOM   3098 H  HB2  . ASP A 1 217 ? -33.023 8.354   69.478 1   39.146  ? 206 ASP A HB2  1 
ATOM   3099 H  HB3  . ASP A 1 217 ? -32.333 8.012   70.861 1   39.105  ? 206 ASP A HB3  1 
ATOM   3100 N  N    . GLY A 1 218 ? -29.888 10.999  70.835 1   30.572  ? 207 GLY A N    1 
ATOM   3101 C  CA   . GLY A 1 218 ? -29.246 11.604  71.994 1   37.483  ? 207 GLY A CA   1 
ATOM   3102 C  C    . GLY A 1 218 ? -27.718 11.375  72.075 1   35.377  ? 207 GLY A C    1 
ATOM   3103 O  O    . GLY A 1 218 ? -27.116 11.8    73.016 1   33.146  ? 207 GLY A O    1 
ATOM   3104 H  H    . GLY A 1 218 ? -29.981 11.49   70.069 1   32.678  ? 207 GLY A H    1 
ATOM   3105 H  HA2  . GLY A 1 218 ? -29.421 12.574  71.975 1   35.236  ? 207 GLY A HA2  1 
ATOM   3106 H  HA3  . GLY A 1 218 ? -29.667 11.246  72.811 1   35.221  ? 207 GLY A HA3  1 
ATOM   3107 N  N    . CYS A 1 219 ? -27.076 10.731  71.134 1   35.076  ? 208 CYS A N    1 
ATOM   3108 C  CA   . CYS A 1 219 ? -25.715 10.258  71.389 1   35.014  ? 208 CYS A CA   1 
ATOM   3109 C  C    . CYS A 1 219 ? -24.729 11.391  71.169 1   26.632  ? 208 CYS A C    1 
ATOM   3110 O  O    . CYS A 1 219 ? -24.051 11.816  72.089 1   32.898  ? 208 CYS A O    1 
ATOM   3111 C  CB   . CYS A 1 219 ? -25.437 8.984   70.587 1   33.981  ? 208 CYS A CB   1 
ATOM   3112 S  SG   . CYS A 1 219 ? -23.812 8.235   70.836 1   36.816  ? 208 CYS A SG   1 
ATOM   3113 H  H    . CYS A 1 219 ? -27.464 10.577  70.32  1   35.093  ? 208 CYS A H    1 
ATOM   3114 H  HA   . CYS A 1 219 ? -25.665 9.997   72.344 1   33.119  ? 208 CYS A HA   1 
ATOM   3115 H  HB2  . CYS A 1 219 ? -26.119 8.314   70.817 1   34.752  ? 208 CYS A HB2  1 
ATOM   3116 H  HB3  . CYS A 1 219 ? -25.534 9.188   69.63  1   34.697  ? 208 CYS A HB3  1 
ATOM   3117 H  HG   . CYS A 1 219 ? -23.957 7.302   70.073 0   36.8    ? 208 CYS A HG   1 
ATOM   3118 N  N    . PHE A 1 220 ? -24.561 11.858  69.948 1   26.691  ? 209 PHE A N    1 
ATOM   3119 C  CA   . PHE A 1 220 ? -23.699 13.016  69.741 1   29.465  ? 209 PHE A CA   1 
ATOM   3120 C  C    . PHE A 1 220 ? -24.14  13.78   68.49  1   35.437  ? 209 PHE A C    1 
ATOM   3121 O  O    . PHE A 1 220 ? -24.239 13.2    67.412 1   30.211  ? 209 PHE A O    1 
ATOM   3122 C  CB   . PHE A 1 220 ? -22.223 12.566  69.544 1   36.258  ? 209 PHE A CB   1 
ATOM   3123 C  CG   . PHE A 1 220 ? -21.25  13.738  69.487 1   30.414  ? 209 PHE A CG   1 
ATOM   3124 C  CD1  . PHE A 1 220 ? -20.78  14.297  70.656 1   37.273  ? 209 PHE A CD1  1 
ATOM   3125 C  CD2  . PHE A 1 220 ? -20.992 14.373  68.287 1   35.493  ? 209 PHE A CD2  1 
ATOM   3126 C  CE1  . PHE A 1 220 ? -20.007 15.453  70.62  1   38.504  ? 209 PHE A CE1  1 
ATOM   3127 C  CE2  . PHE A 1 220 ? -20.208 15.495  68.234 1   39.746  ? 209 PHE A CE2  1 
ATOM   3128 C  CZ   . PHE A 1 220 ? -19.734 16.05   69.407 1   34.934  ? 209 PHE A CZ   1 
ATOM   3129 H  H    . PHE A 1 220 ? -24.977 11.466  69.235 1   27.445  ? 209 PHE A H    1 
ATOM   3130 H  HA   . PHE A 1 220 ? -23.752 13.607  70.53  1   31.078  ? 209 PHE A HA   1 
ATOM   3131 H  HB2  . PHE A 1 220 ? -21.972 11.975  70.289 1   33.251  ? 209 PHE A HB2  1 
ATOM   3132 H  HB3  . PHE A 1 220 ? -22.158 12.054  68.708 1   33.237  ? 209 PHE A HB3  1 
ATOM   3133 H  HD1  . PHE A 1 220 ? -21.001 13.905  71.485 1   35.832  ? 209 PHE A HD1  1 
ATOM   3134 H  HD2  . PHE A 1 220 ? -21.343 14.012  67.49  1   35.218  ? 209 PHE A HD2  1 
ATOM   3135 H  HE1  . PHE A 1 220 ? -19.653 15.812  71.418 1   37.312  ? 209 PHE A HE1  1 
ATOM   3136 H  HE2  . PHE A 1 220 ? -20.012 15.898  67.403 1   37.51   ? 209 PHE A HE2  1 
ATOM   3137 H  HZ   . PHE A 1 220 ? -19.164 16.802  69.373 1   36.87   ? 209 PHE A HZ   1 
ATOM   3138 N  N    . PRO A 1 221 ? -24.323 15.123  68.547 1   35.504  ? 210 PRO A N    1 
ATOM   3139 C  CA   . PRO A 1 221 ? -24.273 15.883  69.803 1   33.075  ? 210 PRO A CA   1 
ATOM   3140 C  C    . PRO A 1 221 ? -25.236 15.381  70.854 1   34.785  ? 210 PRO A C    1 
ATOM   3141 O  O    . PRO A 1 221 ? -26.283 14.831  70.573 1   34.41   ? 210 PRO A O    1 
ATOM   3142 C  CB   . PRO A 1 221 ? -24.549 17.35   69.454 1   34.485  ? 210 PRO A CB   1 
ATOM   3143 C  CG   . PRO A 1 221 ? -24.259 17.374  67.952 1   31.114  ? 210 PRO A CG   1 
ATOM   3144 C  CD   . PRO A 1 221 ? -24.49  15.976  67.368 1   34.417  ? 210 PRO A CD   1 
ATOM   3145 H  HA   . PRO A 1 221 ? -23.349 15.811  70.148 1   34.034  ? 210 PRO A HA   1 
ATOM   3146 H  HB2  . PRO A 1 221 ? -25.486 17.593  69.641 1   33.396  ? 210 PRO A HB2  1 
ATOM   3147 H  HB3  . PRO A 1 221 ? -23.943 17.954  69.944 1   33.383  ? 210 PRO A HB3  1 
ATOM   3148 H  HG2  . PRO A 1 221 ? -24.846 18.021  67.508 1   32.66   ? 210 PRO A HG2  1 
ATOM   3149 H  HG3  . PRO A 1 221 ? -23.332 17.651  67.795 1   32.594  ? 210 PRO A HG3  1 
ATOM   3150 H  HD2  . PRO A 1 221 ? -25.393 15.893  66.991 1   33.942  ? 210 PRO A HD2  1 
ATOM   3151 H  HD3  . PRO A 1 221 ? -23.824 15.765  66.676 1   33.893  ? 210 PRO A HD3  1 
ATOM   3152 N  N    . PRO A 1 222 ? -24.811 15.504  72.122 1   34.142  ? 211 PRO A N    1 
ATOM   3153 C  CA   . PRO A 1 222 ? -25.468 14.804  73.193 1   30.903  ? 211 PRO A CA   1 
ATOM   3154 C  C    . PRO A 1 222 ? -26.838 15.448  73.327 1   35.914  ? 211 PRO A C    1 
ATOM   3155 O  O    . PRO A 1 222 ? -26.946 16.664  73.367 1   34.609  ? 211 PRO A O    1 
ATOM   3156 C  CB   . PRO A 1 222 ? -24.578 15.052  74.409 1   31.794  ? 211 PRO A CB   1 
ATOM   3157 C  CG   . PRO A 1 222 ? -23.833 16.345  74.112 1   31.98   ? 211 PRO A CG   1 
ATOM   3158 C  CD   . PRO A 1 222 ? -23.66  16.317  72.558 1   31.482  ? 211 PRO A CD   1 
ATOM   3159 H  HA   . PRO A 1 222 ? -25.539 13.838  72.995 1   32.575  ? 211 PRO A HA   1 
ATOM   3160 H  HB2  . PRO A 1 222 ? -25.121 15.143  75.227 1   31.656  ? 211 PRO A HB2  1 
ATOM   3161 H  HB3  . PRO A 1 222 ? -23.945 14.306  74.536 1   31.638  ? 211 PRO A HB3  1 
ATOM   3162 H  HG2  . PRO A 1 222 ? -24.354 17.125  74.393 1   31.828  ? 211 PRO A HG2  1 
ATOM   3163 H  HG3  . PRO A 1 222 ? -22.962 16.361  74.562 1   31.828  ? 211 PRO A HG3  1 
ATOM   3164 H  HD2  . PRO A 1 222 ? -23.7   17.224  72.182 1   32.217  ? 211 PRO A HD2  1 
ATOM   3165 H  HD3  . PRO A 1 222 ? -22.809 15.895  72.305 1   32.214  ? 211 PRO A HD3  1 
ATOM   3166 N  N    . GLY A 1 223 ? -27.857 14.633  73.513 1   35.265  ? 212 GLY A N    1 
ATOM   3167 C  CA   . GLY A 1 223 ? -29.167 15.194  73.813 1   43.499  ? 212 GLY A CA   1 
ATOM   3168 C  C    . GLY A 1 223 ? -29.955 15.626  72.576 1   45.504  ? 212 GLY A C    1 
ATOM   3169 O  O    . GLY A 1 223 ? -31.096 16.017  72.715 1   45.399  ? 212 GLY A O    1 
ATOM   3170 H  H    . GLY A 1 223 ? -27.75  13.727  73.464 1   37.028  ? 212 GLY A H    1 
ATOM   3171 H  HA2  . GLY A 1 223 ? -29.69  14.519  74.303 1   41.768  ? 212 GLY A HA2  1 
ATOM   3172 H  HA3  . GLY A 1 223 ? -29.053 15.97   74.412 1   41.704  ? 212 GLY A HA3  1 
ATOM   3173 N  N    . TYR A 1 224 ? -29.382 15.523  71.374 1   40.9    ? 213 TYR A N    1 
ATOM   3174 C  CA   . TYR A 1 224 ? -30.093 15.859  70.151 1   36.984  ? 213 TYR A CA   1 
ATOM   3175 C  C    . TYR A 1 224 ? -30.701 14.635  69.48  1   41.804  ? 213 TYR A C    1 
ATOM   3176 O  O    . TYR A 1 224 ? -30.026 13.621  69.265 1   38.496  ? 213 TYR A O    1 
ATOM   3177 C  CB   . TYR A 1 224 ? -29.113 16.457  69.182 1   38.068  ? 213 TYR A CB   1 
ATOM   3178 C  CG   . TYR A 1 224 ? -29.782 17.011  67.958 1   42.448  ? 213 TYR A CG   1 
ATOM   3179 C  CD1  . TYR A 1 224 ? -30.348 18.29   67.974 1   50.985  ? 213 TYR A CD1  1 
ATOM   3180 C  CD2  . TYR A 1 224 ? -29.886 16.245  66.829 1   35.654  ? 213 TYR A CD2  1 
ATOM   3181 C  CE1  . TYR A 1 224 ? -30.919 18.822  66.833 1   45.17   ? 213 TYR A CE1  1 
ATOM   3182 C  CE2  . TYR A 1 224 ? -30.484 16.748  65.68  1   43.016  ? 213 TYR A CE2  1 
ATOM   3183 C  CZ   . TYR A 1 224 ? -31.015 18.033  65.692 1   46.156  ? 213 TYR A CZ   1 
ATOM   3184 O  OH   . TYR A 1 224 ? -31.592 18.498  64.55  1   39.773  ? 213 TYR A OH   1 
ATOM   3185 H  H    . TYR A 1 224 ? -28.521 15.226  71.309 1   40.923  ? 213 TYR A H    1 
ATOM   3186 H  HA   . TYR A 1 224 ? -30.804 16.524  70.35  1   38.843  ? 213 TYR A HA   1 
ATOM   3187 H  HB2  . TYR A 1 224 ? -28.622 17.178  69.634 1   38.773  ? 213 TYR A HB2  1 
ATOM   3188 H  HB3  . TYR A 1 224 ? -28.468 15.765  68.913 1   38.77   ? 213 TYR A HB3  1 
ATOM   3189 H  HD1  . TYR A 1 224 ? -30.266 18.826  68.746 1   47.317  ? 213 TYR A HD1  1 
ATOM   3190 H  HD2  . TYR A 1 224 ? -29.514 15.377  66.818 1   38.934  ? 213 TYR A HD2  1 
ATOM   3191 H  HE1  . TYR A 1 224 ? -31.291 19.688  66.844 1   46.526  ? 213 TYR A HE1  1 
ATOM   3192 H  HE2  . TYR A 1 224 ? -30.537 16.221  64.902 1   41.878  ? 213 TYR A HE2  1 
ATOM   3193 H  HH   . TYR A 1 224 ? -31.001 18.876  64.047 0   39.78   ? 213 TYR A HH   1 
ATOM   3194 N  N    . ALA A 1 225 ? -32.005 14.765  69.202 1   38.588  ? 214 ALA A N    1 
ATOM   3195 C  CA   . ALA A 1 225 ? -32.805 13.834  68.408 1   43.994  ? 214 ALA A CA   1 
ATOM   3196 C  C    . ALA A 1 225 ? -33.059 14.375  66.993 1   38.232  ? 214 ALA A C    1 
ATOM   3197 O  O    . ALA A 1 225 ? -32.73  13.728  66.003 1   36.722  ? 214 ALA A O    1 
ATOM   3198 C  CB   . ALA A 1 225 ? -34.106 13.588  69.169 1   39.102  ? 214 ALA A CB   1 
ATOM   3199 H  H    . ALA A 1 225 ? -32.433 15.498  69.54  1   40.466  ? 214 ALA A H    1 
ATOM   3200 H  HA   . ALA A 1 225 ? -32.305 12.975  68.329 1   40.912  ? 214 ALA A HA   1 
ATOM   3201 H  HB1  . ALA A 1 225 ? -33.916 13.111  69.994 1   40.538  ? 214 ALA A HB1  1 
ATOM   3202 H  HB2  . ALA A 1 225 ? -34.53  14.436  69.381 1   40.499  ? 214 ALA A HB2  1 
ATOM   3203 H  HB3  . ALA A 1 225 ? -34.709 13.055  68.623 1   40.559  ? 214 ALA A HB3  1 
ATOM   3204 N  N    . GLY A 1 226 ? -33.825 15.478  66.916 1   40.573  ? 215 GLY A N    1 
ATOM   3205 C  CA   . GLY A 1 226 ? -33.95  16.282  65.713 1   38.832  ? 215 GLY A CA   1 
ATOM   3206 C  C    . GLY A 1 226 ? -35.084 15.92   64.747 1   33.345  ? 215 GLY A C    1 
ATOM   3207 O  O    . GLY A 1 226 ? -35.079 16.444  63.656 1   35.559  ? 215 GLY A O    1 
ATOM   3208 H  H    . GLY A 1 226 ? -34.288 15.742  67.658 1   39.64   ? 215 GLY A H    1 
ATOM   3209 H  HA2  . GLY A 1 226 ? -34.064 17.222  65.988 1   37.934  ? 215 GLY A HA2  1 
ATOM   3210 H  HA3  . GLY A 1 226 ? -33.1   16.228  65.222 1   37.974  ? 215 GLY A HA3  1 
ATOM   3211 N  N    . GLU A 1 227 ? -35.976 14.98   65.047 1   40.239  ? 216 GLU A N    1 
ATOM   3212 C  CA   . GLU A 1 227 ? -37.077 14.615  64.144 1   42.982  ? 216 GLU A CA   1 
ATOM   3213 C  C    . GLU A 1 227 ? -37.879 15.831  63.672 1   41.926  ? 216 GLU A C    1 
ATOM   3214 O  O    . GLU A 1 227 ? -38.246 15.896  62.501 1   46.07   ? 216 GLU A O    1 
ATOM   3215 C  CB   . GLU A 1 227 ? -37.997 13.503  64.663 1   43.595  ? 216 GLU A CB   1 
ATOM   3216 C  CG   . GLU A 1 227 ? -38.802 13.799  65.928 1   53.485  ? 216 GLU A CG   1 
ATOM   3217 C  CD   . GLU A 1 227 ? -38.051 13.657  67.237 1   61.164  ? 216 GLU A CD   1 
ATOM   3218 O  OE1  . GLU A 1 227 ? -36.814 13.773  67.204 1   55.071  ? 216 GLU A OE1  1 
ATOM   3219 O  OE2  . GLU A 1 227 ? -38.693 13.469  68.283 1   55.926  ? 216 GLU A OE2  1 
ATOM   3220 H  H    . GLU A 1 227 ? -35.9   14.537  65.843 1   39.155  ? 216 GLU A H    1 
ATOM   3221 H  HA   . GLU A 1 227 ? -36.655 14.231  63.334 1   42.378  ? 216 GLU A HA   1 
ATOM   3222 H  HB2  . GLU A 1 227 ? -38.633 13.274  63.954 1   45.563  ? 216 GLU A HB2  1 
ATOM   3223 H  HB3  . GLU A 1 227 ? -37.452 12.707  64.835 1   45.604  ? 216 GLU A HB3  1 
ATOM   3224 H  HG2  . GLU A 1 227 ? -39.15  14.715  65.873 1   52.604  ? 216 GLU A HG2  1 
ATOM   3225 H  HG3  . GLU A 1 227 ? -39.577 13.199  65.953 1   52.648  ? 216 GLU A HG3  1 
ATOM   3226 N  N    . ASP A 1 228 ? -37.971 16.88   64.485 1   41.681  ? 217 ASP A N    1 
ATOM   3227 C  CA   . ASP A 1 228 ? -38.781 18.038  64.115 1   51.915  ? 217 ASP A CA   1 
ATOM   3228 C  C    . ASP A 1 228 ? -37.978 19.029  63.285 1   55.459  ? 217 ASP A C    1 
ATOM   3229 O  O    . ASP A 1 228 ? -38.578 19.954  62.768 1   45.804  ? 217 ASP A O    1 
ATOM   3230 C  CB   . ASP A 1 228 ? -39.441 18.695  65.331 1   51.708  ? 217 ASP A CB   1 
ATOM   3231 C  CG   . ASP A 1 228 ? -40.468 17.852  66.129 1   62.411  ? 217 ASP A CG   1 
ATOM   3232 O  OD1  . ASP A 1 228 ? -41.028 16.819  65.61  1   66.644  ? 217 ASP A OD1  1 
ATOM   3233 O  OD2  . ASP A 1 228 ? -40.698 18.174  67.322 1   52.563  ? 217 ASP A OD2  1 
ATOM   3234 H  H    . ASP A 1 228 ? -37.542 16.878  65.291 1   43.745  ? 217 ASP A H    1 
ATOM   3235 H  HA   . ASP A 1 228 ? -39.526 17.718  63.556 1   50.314  ? 217 ASP A HA   1 
ATOM   3236 H  HB2  . ASP A 1 228 ? -38.733 18.965  65.952 1   53.948  ? 217 ASP A HB2  1 
ATOM   3237 H  HB3  . ASP A 1 228 ? -39.896 19.509  65.032 1   53.966  ? 217 ASP A HB3  1 
ATOM   3238 N  N    . ASP A 1 229 ? -36.638 18.898  63.198 1   50.941  ? 218 ASP A N    1 
ATOM   3239 C  CA   . ASP A 1 229 ? -35.821 19.771  62.353 1   40.196  ? 218 ASP A CA   1 
ATOM   3240 C  C    . ASP A 1 229 ? -35.819 19.269  60.91  1   47.278  ? 218 ASP A C    1 
ATOM   3241 O  O    . ASP A 1 229 ? -35.199 18.252  60.568 1   46.847  ? 218 ASP A O    1 
ATOM   3242 C  CB   . ASP A 1 229 ? -34.446 20.039  62.961 1   49.082  ? 218 ASP A CB   1 
ATOM   3243 C  CG   . ASP A 1 229 ? -34.458 20.544  64.404 1   60.937  ? 218 ASP A CG   1 
ATOM   3244 O  OD1  . ASP A 1 229 ? -35.472 21.157  64.832 1   55.945  ? 218 ASP A OD1  1 
ATOM   3245 O  OD2  . ASP A 1 229 ? -33.511 20.22   65.144 1   57.802  ? 218 ASP A OD2  1 
ATOM   3246 H  H    . ASP A 1 229 ? -36.219 18.25   63.687 1   49.069  ? 218 ASP A H    1 
ATOM   3247 H  HA   . ASP A 1 229 ? -36.249 20.656  62.352 1   45.206  ? 218 ASP A HA   1 
ATOM   3248 H  HB2  . ASP A 1 229 ? -33.924 19.21   62.933 1   49.328  ? 218 ASP A HB2  1 
ATOM   3249 H  HB3  . ASP A 1 229 ? -33.984 20.704  62.409 1   49.29   ? 218 ASP A HB3  1 
ATOM   3250 N  N    . ARG A 1 230 ? -36.531 20.026  60.061 1   51.631  ? 219 ARG A N    1 
ATOM   3251 C  CA   . ARG A 1 230 ? -36.951 19.58   58.738 1   48.575  ? 219 ARG A CA   1 
ATOM   3252 C  C    . ARG A 1 230 ? -36.342 20.471  57.668 1   40.929  ? 219 ARG A C    1 
ATOM   3253 O  O    . ARG A 1 230 ? -36.452 20.176  56.476 1   41.277  ? 219 ARG A O    1 
ATOM   3254 C  CB   . ARG A 1 230 ? -38.474 19.618  58.537 1   49.398  ? 219 ARG A CB   1 
ATOM   3255 C  CG   . ARG A 1 230 ? -39.306 18.821  59.532 1   55.285  ? 219 ARG A CG   1 
ATOM   3256 C  CD   . ARG A 1 230 ? -39.174 17.294  59.469 1   61.186  ? 219 ARG A CD   1 
ATOM   3257 N  NE   . ARG A 1 230 ? -38.73  16.749  58.175 1   66.695  ? 219 ARG A NE   1 
ATOM   3258 C  CZ   . ARG A 1 230 ? -39.434 16.624  57.044 1   69.151  ? 219 ARG A CZ   1 
ATOM   3259 N  NH1  . ARG A 1 230 ? -40.778 16.635  57.039 1   56.84   ? 219 ARG A NH1  1 
ATOM   3260 N  NH2  . ARG A 1 230 ? -38.75  16.459  55.918 1   62.735  ? 219 ARG A NH2  1 
ATOM   3261 H  H    . ARG A 1 230 ? -36.787 20.861  60.333 1   49.666  ? 219 ARG A H    1 
ATOM   3262 H  HA   . ARG A 1 230 ? -36.633 18.653  58.601 1   47.73   ? 219 ARG A HA   1 
ATOM   3263 H  HB2  . ARG A 1 230 ? -38.762 20.555  58.579 1   50.447  ? 219 ARG A HB2  1 
ATOM   3264 H  HB3  . ARG A 1 230 ? -38.674 19.293  57.634 1   50.526  ? 219 ARG A HB3  1 
ATOM   3265 H  HG2  . ARG A 1 230 ? -39.068 19.113  60.438 1   55.056  ? 219 ARG A HG2  1 
ATOM   3266 H  HG3  . ARG A 1 230 ? -40.251 19.054  59.402 1   55.118  ? 219 ARG A HG3  1 
ATOM   3267 H  HD2  . ARG A 1 230 ? -38.54  17.017  60.161 1   60.807  ? 219 ARG A HD2  1 
ATOM   3268 H  HD3  . ARG A 1 230 ? -40.042 16.902  59.696 1   60.983  ? 219 ARG A HD3  1 
ATOM   3269 H  HE   . ARG A 1 230 ? -37.905 16.47   58.137 1   65.897  ? 219 ARG A HE   1 
ATOM   3270 H  HH11 . ARG A 1 230 ? -41.226 16.347  57.744 1   60.357  ? 219 ARG A HH11 1 
ATOM   3271 H  HH12 . ARG A 1 230 ? -41.21  16.931  56.327 1   60.375  ? 219 ARG A HH12 1 
ATOM   3272 H  HH21 . ARG A 1 230 ? -37.978 16.876  55.807 1   64.669  ? 219 ARG A HH21 1 
ATOM   3273 H  HH22 . ARG A 1 230 ? -39.07  15.932  55.284 1   64.65   ? 219 ARG A HH22 1 
ATOM   3274 N  N    . GLY A 1 231 ? -35.654 21.545  58.083 1   45.068  ? 220 GLY A N    1 
ATOM   3275 C  CA   . GLY A 1 231 ? -35.245 22.555  57.116 1   49.503  ? 220 GLY A CA   1 
ATOM   3276 C  C    . GLY A 1 231 ? -35.988 23.871  57.33  1   50.447  ? 220 GLY A C    1 
ATOM   3277 O  O    . GLY A 1 231 ? -37.003 23.89   58.013 1   49.601  ? 220 GLY A O    1 
ATOM   3278 H  H    . GLY A 1 231 ? -35.421 21.646  58.961 1   45.098  ? 220 GLY A H    1 
ATOM   3279 H  HA2  . GLY A 1 231 ? -34.275 22.708  57.203 1   48.589  ? 220 GLY A HA2  1 
ATOM   3280 H  HA3  . GLY A 1 231 ? -35.418 22.225  56.205 1   48.495  ? 220 GLY A HA3  1 
ATOM   3281 N  N    . VAL A 1 232 ? -35.434 24.938  56.76  1   46.382  ? 221 VAL A N    1 
ATOM   3282 C  CA   . VAL A 1 232 ? -35.844 26.311  57.007 1   48.905  ? 221 VAL A CA   1 
ATOM   3283 C  C    . VAL A 1 232 ? -35.949 27.015  55.654 1   59.398  ? 221 VAL A C    1 
ATOM   3284 O  O    . VAL A 1 232 ? -35.148 26.768  54.745 1   43.88   ? 221 VAL A O    1 
ATOM   3285 C  CB   . VAL A 1 232 ? -34.843 26.997  57.953 1   54.847  ? 221 VAL A CB   1 
ATOM   3286 C  CG1  . VAL A 1 232 ? -35.008 28.518  58.017 1   65.229  ? 221 VAL A CG1  1 
ATOM   3287 C  CG2  . VAL A 1 232 ? -34.953 26.398  59.357 1   57.263  ? 221 VAL A CG2  1 
ATOM   3288 H  H    . VAL A 1 232 ? -34.748 24.798  56.173 1   47.974  ? 221 VAL A H    1 
ATOM   3289 H  HA   . VAL A 1 232 ? -36.724 26.305  57.431 1   51.352  ? 221 VAL A HA   1 
ATOM   3290 H  HB   . VAL A 1 232 ? -33.938 26.803  57.611 1   55.893  ? 221 VAL A HB   1 
ATOM   3291 H  HG11 . VAL A 1 232 ? -35.951 28.739  58.094 1   61.972  ? 221 VAL A HG11 1 
ATOM   3292 H  HG12 . VAL A 1 232 ? -34.646 28.919  57.208 1   61.963  ? 221 VAL A HG12 1 
ATOM   3293 H  HG13 . VAL A 1 232 ? -34.53  28.865  58.789 1   61.92   ? 221 VAL A HG13 1 
ATOM   3294 H  HG21 . VAL A 1 232 ? -34.376 26.889  59.966 1   56.551  ? 221 VAL A HG21 1 
ATOM   3295 H  HG22 . VAL A 1 232 ? -34.68  25.466  59.335 1   56.455  ? 221 VAL A HG22 1 
ATOM   3296 H  HG23 . VAL A 1 232 ? -35.873 26.458  59.664 1   56.494  ? 221 VAL A HG23 1 
ATOM   3297 N  N    . GLY A 1 233 ? -37.026 27.799  55.485 1   62.703  ? 222 GLY A N    1 
ATOM   3298 C  CA   . GLY A 1 233 ? -37.226 28.56   54.265 1   55.049  ? 222 GLY A CA   1 
ATOM   3299 C  C    . GLY A 1 233 ? -37.369 27.631  53.065 1   49.199  ? 222 GLY A C    1 
ATOM   3300 O  O    . GLY A 1 233 ? -38.171 26.682  53.071 1   51.035  ? 222 GLY A O    1 
ATOM   3301 H  H    . GLY A 1 233 ? -37.651 27.86   56.15  1   59.94   ? 222 GLY A H    1 
ATOM   3302 H  HA2  . GLY A 1 233 ? -38.038 29.112  54.356 1   55.368  ? 222 GLY A HA2  1 
ATOM   3303 H  HA3  . GLY A 1 233 ? -36.459 29.164  54.131 1   55.305  ? 222 GLY A HA3  1 
ATOM   3304 N  N    . ALA A 1 234 ? -36.547 27.873  52.046 1   48.971  ? 223 ALA A N    1 
ATOM   3305 C  CA   . ALA A 1 234 ? -36.601 27.028  50.854 1   54.844  ? 223 ALA A CA   1 
ATOM   3306 C  C    . ALA A 1 234 ? -36.235 25.58   51.191 1   59.303  ? 223 ALA A C    1 
ATOM   3307 O  O    . ALA A 1 234 ? -36.631 24.658  50.471 1   53.226  ? 223 ALA A O    1 
ATOM   3308 C  CB   . ALA A 1 234 ? -35.692 27.587  49.76  1   58.756  ? 223 ALA A CB   1 
ATOM   3309 H  H    . ALA A 1 234 ? -35.948 28.563  52.083 1   50.405  ? 223 ALA A H    1 
ATOM   3310 H  HA   . ALA A 1 234 ? -37.54  27.034  50.519 1   55.055  ? 223 ALA A HA   1 
ATOM   3311 H  HB1  . ALA A 1 234 ? -35.983 28.483  49.52  1   57.579  ? 223 ALA A HB1  1 
ATOM   3312 H  HB2  . ALA A 1 234 ? -34.776 27.623  50.083 1   57.579  ? 223 ALA A HB2  1 
ATOM   3313 H  HB3  . ALA A 1 234 ? -35.734 27.015  48.976 1   57.579  ? 223 ALA A HB3  1 
ATOM   3314 N  N    . GLY A 1 235 ? -35.526 25.393  52.324 1   58.793  ? 224 GLY A N    1 
ATOM   3315 C  CA   . GLY A 1 235 ? -35.006 24.096  52.709 1   50.999  ? 224 GLY A CA   1 
ATOM   3316 C  C    . GLY A 1 235 ? -36.007 23.236  53.443 1   52.704  ? 224 GLY A C    1 
ATOM   3317 O  O    . GLY A 1 235 ? -35.714 22.067  53.692 1   45.696  ? 224 GLY A O    1 
ATOM   3318 H  H    . GLY A 1 235 ? -35.344 26.108  52.863 1   56.896  ? 224 GLY A H    1 
ATOM   3319 H  HA2  . GLY A 1 235 ? -34.706 23.621  51.898 1   53.178  ? 224 GLY A HA2  1 
ATOM   3320 H  HA3  . GLY A 1 235 ? -34.216 24.232  53.283 1   53.128  ? 224 GLY A HA3  1 
ATOM   3321 N  N    . GLU A 1 236 ? -37.208 23.763  53.708 1   50.423  ? 225 GLU A N    1 
ATOM   3322 C  CA   . GLU A 1 236 ? -38.15  23.016  54.522 1   47.768  ? 225 GLU A CA   1 
ATOM   3323 C  C    . GLU A 1 236 ? -38.675 21.762  53.805 1   46.489  ? 225 GLU A C    1 
ATOM   3324 O  O    . GLU A 1 236 ? -39.159 21.843  52.675 1   49.133  ? 225 GLU A O    1 
ATOM   3325 C  CB   . GLU A 1 236 ? -39.242 23.966  55.009 1   57.245  ? 225 GLU A CB   1 
ATOM   3326 C  CG   . GLU A 1 236 ? -40.293 23.27   55.877 1   71.627  ? 225 GLU A CG   1 
ATOM   3327 C  CD   . GLU A 1 236 ? -41.361 24.199  56.471 1   94.795  ? 225 GLU A CD   1 
ATOM   3328 O  OE1  . GLU A 1 236 ? -41.325 25.438  56.206 1   70.993  ? 225 GLU A OE1  1 
ATOM   3329 O  OE2  . GLU A 1 236 ? -42.254 23.673  57.189 1   79.945  ? 225 GLU A OE2  1 
ATOM   3330 H  H    . GLU A 1 236 ? -37.443 24.585  53.387 1   50.501  ? 225 GLU A H    1 
ATOM   3331 H  HA   . GLU A 1 236 ? -37.664 22.712  55.33  1   49.653  ? 225 GLU A HA   1 
ATOM   3332 H  HB2  . GLU A 1 236 ? -38.826 24.689  55.524 1   57.857  ? 225 GLU A HB2  1 
ATOM   3333 H  HB3  . GLU A 1 236 ? -39.682 24.368  54.231 1   57.809  ? 225 GLU A HB3  1 
ATOM   3334 H  HG2  . GLU A 1 236 ? -40.747 22.586  55.34  1   72.415  ? 225 GLU A HG2  1 
ATOM   3335 H  HG3  . GLU A 1 236 ? -39.84  22.809  56.615 1   72.541  ? 225 GLU A HG3  1 
ATOM   3336 N  N    . GLY A 1 237 ? -38.617 20.585  54.478 1   49.112  ? 226 GLY A N    1 
ATOM   3337 C  CA   . GLY A 1 237 ? -38.889 19.282  53.862 1   39.009  ? 226 GLY A CA   1 
ATOM   3338 C  C    . GLY A 1 237 ? -37.645 18.573  53.287 1   42.298  ? 226 GLY A C    1 
ATOM   3339 O  O    . GLY A 1 237 ? -37.727 17.389  52.936 1   40.854  ? 226 GLY A O    1 
ATOM   3340 H  H    . GLY A 1 237 ? -38.399 20.603  55.365 1   46.062  ? 226 GLY A H    1 
ATOM   3341 H  HA2  . GLY A 1 237 ? -39.303 18.698  54.541 1   42.058  ? 226 GLY A HA2  1 
ATOM   3342 H  HA3  . GLY A 1 237 ? -39.549 19.406  53.14  1   42.033  ? 226 GLY A HA3  1 
ATOM   3343 N  N    . TYR A 1 238 ? -36.49  19.263  53.252 1   40.468  ? 227 TYR A N    1 
ATOM   3344 C  CA   . TYR A 1 238 ? -35.24  18.77   52.652 1   47.563  ? 227 TYR A CA   1 
ATOM   3345 C  C    . TYR A 1 238 ? -34.184 18.335  53.695 1   43.633  ? 227 TYR A C    1 
ATOM   3346 O  O    . TYR A 1 238 ? -33.039 18.1    53.339 1   45.153  ? 227 TYR A O    1 
ATOM   3347 C  CB   . TYR A 1 238 ? -34.699 19.795  51.632 1   53.143  ? 227 TYR A CB   1 
ATOM   3348 C  CG   . TYR A 1 238 ? -35.655 19.938  50.451 1   54.114  ? 227 TYR A CG   1 
ATOM   3349 C  CD1  . TYR A 1 238 ? -35.577 19.089  49.347 1   62.155  ? 227 TYR A CD1  1 
ATOM   3350 C  CD2  . TYR A 1 238 ? -36.702 20.855  50.491 1   63.597  ? 227 TYR A CD2  1 
ATOM   3351 C  CE1  . TYR A 1 238 ? -36.475 19.163  48.297 1   59.651  ? 227 TYR A CE1  1 
ATOM   3352 C  CE2  . TYR A 1 238 ? -37.62  20.94   49.458 1   65.852  ? 227 TYR A CE2  1 
ATOM   3353 C  CZ   . TYR A 1 238 ? -37.496 20.099  48.362 1   70.641  ? 227 TYR A CZ   1 
ATOM   3354 O  OH   . TYR A 1 238 ? -38.426 20.182  47.39  1   67.306  ? 227 TYR A OH   1 
ATOM   3355 H  H    . TYR A 1 238 ? -36.477 20.095  53.629 1   42.459  ? 227 TYR A H    1 
ATOM   3356 H  HA   . TYR A 1 238 ? -35.475 17.955  52.134 1   46.282  ? 227 TYR A HA   1 
ATOM   3357 H  HB2  . TYR A 1 238 ? -34.595 20.665  52.072 1   52.039  ? 227 TYR A HB2  1 
ATOM   3358 H  HB3  . TYR A 1 238 ? -33.829 19.487  51.301 1   52.045  ? 227 TYR A HB3  1 
ATOM   3359 H  HD1  . TYR A 1 238 ? -34.884 18.448  49.311 1   59.708  ? 227 TYR A HD1  1 
ATOM   3360 H  HD2  . TYR A 1 238 ? -36.795 21.421  51.241 1   61.777  ? 227 TYR A HD2  1 
ATOM   3361 H  HE1  . TYR A 1 238 ? -36.403 18.585  47.558 1   62.445  ? 227 TYR A HE1  1 
ATOM   3362 H  HE2  . TYR A 1 238 ? -38.32  21.569  49.495 1   66.211  ? 227 TYR A HE2  1 
ATOM   3363 H  HH   . TYR A 1 238 ? -39.08  19.678  47.57  0   66.2    ? 227 TYR A HH   1 
ATOM   3364 N  N    . ASN A 1 239 ? -34.562 18.167  54.964 1   43.524  ? 228 ASN A N    1 
ATOM   3365 C  CA   . ASN A 1 239 ? -33.706 17.642  56.004 1   39.161  ? 228 ASN A CA   1 
ATOM   3366 C  C    . ASN A 1 239 ? -34.505 16.592  56.745 1   41.565  ? 228 ASN A C    1 
ATOM   3367 O  O    . ASN A 1 239 ? -35.63  16.849  57.103 1   41.979  ? 228 ASN A O    1 
ATOM   3368 C  CB   . ASN A 1 239 ? -33.243 18.698  56.995 1   42.657  ? 228 ASN A CB   1 
ATOM   3369 C  CG   . ASN A 1 239 ? -32.216 18.128  57.947 1   39.859  ? 228 ASN A CG   1 
ATOM   3370 O  OD1  . ASN A 1 239 ? -31.093 17.881  57.51  1   45.356  ? 228 ASN A OD1  1 
ATOM   3371 N  ND2  . ASN A 1 239 ? -32.578 17.898  59.207 1   37.092  ? 228 ASN A ND2  1 
ATOM   3372 H  H    . ASN A 1 239 ? -35.415 18.401  55.193 1   42.518  ? 228 ASN A H    1 
ATOM   3373 H  HA   . ASN A 1 239 ? -32.913 17.231  55.597 1   41.123  ? 228 ASN A HA   1 
ATOM   3374 H  HB2  . ASN A 1 239 ? -32.851 19.451  56.509 1   41.183  ? 228 ASN A HB2  1 
ATOM   3375 H  HB3  . ASN A 1 239 ? -34.01  19.027  57.503 1   41.144  ? 228 ASN A HB3  1 
ATOM   3376 H  HD21 . ASN A 1 239 ? -32.061 17.402  59.73  1   37.987  ? 228 ASN A HD21 1 
ATOM   3377 H  HD22 . ASN A 1 239 ? -33.332 18.241  59.525 1   37.992  ? 228 ASN A HD22 1 
ATOM   3378 N  N    . ILE A 1 240 ? -33.978 15.372  56.857 1   41.224  ? 229 ILE A N    1 
ATOM   3379 C  CA   . ILE A 1 240 ? -34.658 14.302  57.571 1   42.503  ? 229 ILE A CA   1 
ATOM   3380 C  C    . ILE A 1 240 ? -33.733 13.712  58.644 1   42.195  ? 229 ILE A C    1 
ATOM   3381 O  O    . ILE A 1 240 ? -32.688 13.181  58.336 1   40.505  ? 229 ILE A O    1 
ATOM   3382 C  CB   . ILE A 1 240 ? -35.043 13.221  56.552 1   41.778  ? 229 ILE A CB   1 
ATOM   3383 C  CG1  . ILE A 1 240 ? -36.038 13.74   55.528 1   53.421  ? 229 ILE A CG1  1 
ATOM   3384 C  CG2  . ILE A 1 240 ? -35.528 11.968  57.249 1   39.786  ? 229 ILE A CG2  1 
ATOM   3385 C  CD1  . ILE A 1 240 ? -36.392 12.78   54.418 1   47.248  ? 229 ILE A CD1  1 
ATOM   3386 H  H    . ILE A 1 240 ? -33.166 15.198  56.476 1   41.57   ? 229 ILE A H    1 
ATOM   3387 H  HA   . ILE A 1 240 ? -35.468 14.65   57.992 1   41.996  ? 229 ILE A HA   1 
ATOM   3388 H  HB   . ILE A 1 240 ? -34.229 12.984  56.066 1   43.517  ? 229 ILE A HB   1 
ATOM   3389 H  HG12 . ILE A 1 240 ? -36.861 13.989  55.997 1   49.071  ? 229 ILE A HG12 1 
ATOM   3390 H  HG13 . ILE A 1 240 ? -35.672 14.553  55.125 1   49.003  ? 229 ILE A HG13 1 
ATOM   3391 H  HG21 . ILE A 1 240 ? -35.912 11.357  56.597 1   40.47   ? 229 ILE A HG21 1 
ATOM   3392 H  HG22 . ILE A 1 240 ? -36.204 12.202  57.906 1   40.429  ? 229 ILE A HG22 1 
ATOM   3393 H  HG23 . ILE A 1 240 ? -34.783 11.531  57.694 1   40.407  ? 229 ILE A HG23 1 
ATOM   3394 H  HD11 . ILE A 1 240 ? -35.584 12.333  54.101 1   48.982  ? 229 ILE A HD11 1 
ATOM   3395 H  HD12 . ILE A 1 240 ? -36.8   13.272  53.68  1   48.983  ? 229 ILE A HD12 1 
ATOM   3396 H  HD13 . ILE A 1 240 ? -37.023 12.112  54.749 1   48.922  ? 229 ILE A HD13 1 
ATOM   3397 N  N    . ASN A 1 241 ? -34.15  13.733  59.891 1   38.363  ? 230 ASN A N    1 
ATOM   3398 C  CA   . ASN A 1 241 ? -33.476 13.087  60.998 1   31.766  ? 230 ASN A CA   1 
ATOM   3399 C  C    . ASN A 1 241 ? -34.264 11.873  61.482 1   43.344  ? 230 ASN A C    1 
ATOM   3400 O  O    . ASN A 1 241 ? -35.468 11.963  61.77  1   36.145  ? 230 ASN A O    1 
ATOM   3401 C  CB   . ASN A 1 241 ? -33.277 14.054  62.15  1   35.356  ? 230 ASN A CB   1 
ATOM   3402 C  CG   . ASN A 1 241 ? -32.26  15.138  61.849 1   40.836  ? 230 ASN A CG   1 
ATOM   3403 O  OD1  . ASN A 1 241 ? -31.269 14.924  61.129 1   42.792  ? 230 ASN A OD1  1 
ATOM   3404 N  ND2  . ASN A 1 241 ? -32.488 16.328  62.384 1   40.377  ? 230 ASN A ND2  1 
ATOM   3405 H  H    . ASN A 1 241 ? -34.92  14.191  60.074 1   37.649  ? 230 ASN A H    1 
ATOM   3406 H  HA   . ASN A 1 241 ? -32.588 12.791  60.699 1   35.766  ? 230 ASN A HA   1 
ATOM   3407 H  HB2  . ASN A 1 241 ? -34.135 14.472  62.363 1   35.71   ? 230 ASN A HB2  1 
ATOM   3408 H  HB3  . ASN A 1 241 ? -32.984 13.555  62.938 1   35.708  ? 230 ASN A HB3  1 
ATOM   3409 H  HD21 . ASN A 1 241 ? -31.816 16.794  62.729 1   40.506  ? 230 ASN A HD21 1 
ATOM   3410 H  HD22 . ASN A 1 241 ? -33.311 16.66   62.395 1   40.468  ? 230 ASN A HD22 1 
ATOM   3411 N  N    . ILE A 1 242 ? -33.593 10.718  61.567 1   38.912  ? 231 ILE A N    1 
ATOM   3412 C  CA   . ILE A 1 242 ? -34.228 9.517   62.11  1   37.988  ? 231 ILE A CA   1 
ATOM   3413 C  C    . ILE A 1 242 ? -33.533 9.095   63.394 1   35.349  ? 231 ILE A C    1 
ATOM   3414 O  O    . ILE A 1 242 ? -32.559 8.348   63.33  1   38.647  ? 231 ILE A O    1 
ATOM   3415 C  CB   . ILE A 1 242 ? -34.124 8.426   61.048 1   34.025  ? 231 ILE A CB   1 
ATOM   3416 C  CG1  . ILE A 1 242 ? -34.586 8.971   59.705 1   36.727  ? 231 ILE A CG1  1 
ATOM   3417 C  CG2  . ILE A 1 242 ? -34.812 7.154   61.509 1   40.453  ? 231 ILE A CG2  1 
ATOM   3418 C  CD1  . ILE A 1 242 ? -34.468 8.06    58.509 1   39.494  ? 231 ILE A CD1  1 
ATOM   3419 H  H    . ILE A 1 242 ? -32.726 10.672  61.284 1   39.596  ? 231 ILE A H    1 
ATOM   3420 H  HA   . ILE A 1 242 ? -35.17  9.696   62.29  1   36.997  ? 231 ILE A HA   1 
ATOM   3421 H  HB   . ILE A 1 242 ? -33.174 8.216   60.95  1   36.397  ? 231 ILE A HB   1 
ATOM   3422 H  HG12 . ILE A 1 242 ? -35.524 9.235   59.792 1   36.715  ? 231 ILE A HG12 1 
ATOM   3423 H  HG13 . ILE A 1 242 ? -34.074 9.782   59.512 1   36.765  ? 231 ILE A HG13 1 
ATOM   3424 H  HG21 . ILE A 1 242 ? -34.862 6.523   60.772 1   38.438  ? 231 ILE A HG21 1 
ATOM   3425 H  HG22 . ILE A 1 242 ? -35.71  7.362   61.816 1   38.432  ? 231 ILE A HG22 1 
ATOM   3426 H  HG23 . ILE A 1 242 ? -34.308 6.753   62.237 1   38.422  ? 231 ILE A HG23 1 
ATOM   3427 H  HD11 . ILE A 1 242 ? -33.548 7.748   58.425 1   38.69   ? 231 ILE A HD11 1 
ATOM   3428 H  HD12 . ILE A 1 242 ? -34.718 8.55    57.703 1   38.66   ? 231 ILE A HD12 1 
ATOM   3429 H  HD13 . ILE A 1 242 ? -35.061 7.293   58.619 1   38.661  ? 231 ILE A HD13 1 
ATOM   3430 N  N    . PRO A 1 243 ? -33.935 9.603   64.566 1   37.008  ? 232 PRO A N    1 
ATOM   3431 C  CA   . PRO A 1 243 ? -33.355 9.161   65.824 1   34.545  ? 232 PRO A CA   1 
ATOM   3432 C  C    . PRO A 1 243 ? -33.836 7.774   66.25  1   38.805  ? 232 PRO A C    1 
ATOM   3433 O  O    . PRO A 1 243 ? -34.88  7.592   66.859 1   42.478  ? 232 PRO A O    1 
ATOM   3434 C  CB   . PRO A 1 243 ? -33.76  10.264  66.785 1   35.906  ? 232 PRO A CB   1 
ATOM   3435 C  CG   . PRO A 1 243 ? -35.065 10.766  66.232 1   42.737  ? 232 PRO A CG   1 
ATOM   3436 C  CD   . PRO A 1 243 ? -34.93  10.662  64.736 1   43.398  ? 232 PRO A CD   1 
ATOM   3437 H  HA   . PRO A 1 243 ? -32.37  9.157   65.734 1   35.985  ? 232 PRO A HA   1 
ATOM   3438 H  HB2  . PRO A 1 243 ? -33.875 9.912   67.699 1   37.072  ? 232 PRO A HB2  1 
ATOM   3439 H  HB3  . PRO A 1 243 ? -33.085 10.982  66.801 1   37.043  ? 232 PRO A HB3  1 
ATOM   3440 H  HG2  . PRO A 1 243 ? -35.811 10.217  66.551 1   41.23   ? 232 PRO A HG2  1 
ATOM   3441 H  HG3  . PRO A 1 243 ? -35.221 11.695  66.501 1   41.279  ? 232 PRO A HG3  1 
ATOM   3442 H  HD2  . PRO A 1 243 ? -35.787 10.416  64.322 1   41.622  ? 232 PRO A HD2  1 
ATOM   3443 H  HD3  . PRO A 1 243 ? -34.616 11.51   64.35  1   41.67   ? 232 PRO A HD3  1 
ATOM   3444 N  N    . LEU A 1 244 ? -33.052 6.777   65.878 1   35.036  ? 233 LEU A N    1 
ATOM   3445 C  CA   . LEU A 1 244 ? -33.298 5.428   66.334 1   34.91   ? 233 LEU A CA   1 
ATOM   3446 C  C    . LEU A 1 244 ? -32.914 5.281   67.796 1   35.379  ? 233 LEU A C    1 
ATOM   3447 O  O    . LEU A 1 244 ? -31.971 5.916   68.296 1   35.498  ? 233 LEU A O    1 
ATOM   3448 C  CB   . LEU A 1 244 ? -32.46  4.477   65.475 1   32.416  ? 233 LEU A CB   1 
ATOM   3449 C  CG   . LEU A 1 244 ? -32.765 4.547   63.989 1   41.641  ? 233 LEU A CG   1 
ATOM   3450 C  CD1  . LEU A 1 244 ? -31.851 3.68    63.188 1   42.313  ? 233 LEU A CD1  1 
ATOM   3451 C  CD2  . LEU A 1 244 ? -34.241 4.137   63.833 1   40.763  ? 233 LEU A CD2  1 
ATOM   3452 H  H    . LEU A 1 244 ? -32.335 6.941   65.336 1   35.897  ? 233 LEU A H    1 
ATOM   3453 H  HA   . LEU A 1 244 ? -34.261 5.221   66.225 1   34.723  ? 233 LEU A HA   1 
ATOM   3454 H  HB2  . LEU A 1 244 ? -31.509 4.694   65.61  1   34.915  ? 233 LEU A HB2  1 
ATOM   3455 H  HB3  . LEU A 1 244 ? -32.617 3.555   65.787 1   34.952  ? 233 LEU A HB3  1 
ATOM   3456 H  HG   . LEU A 1 244 ? -32.661 5.484   63.684 1   39.657  ? 233 LEU A HG   1 
ATOM   3457 H  HD11 . LEU A 1 244 ? -30.952 4.048   63.211 1   42.047  ? 233 LEU A HD11 1 
ATOM   3458 H  HD12 . LEU A 1 244 ? -32.161 3.643   62.267 1   42.088  ? 233 LEU A HD12 1 
ATOM   3459 H  HD13 . LEU A 1 244 ? -31.843 2.782   63.562 1   42.094  ? 233 LEU A HD13 1 
ATOM   3460 H  HD21 . LEU A 1 244 ? -34.813 4.897   64.031 1   40.911  ? 233 LEU A HD21 1 
ATOM   3461 H  HD22 . LEU A 1 244 ? -34.446 3.41    64.445 1   40.891  ? 233 LEU A HD22 1 
ATOM   3462 H  HD23 . LEU A 1 244 ? -34.402 3.844   62.92  1   40.986  ? 233 LEU A HD23 1 
ATOM   3463 N  N    . LEU A 1 245 ? -33.554 4.289   68.42  1   38.234  ? 234 LEU A N    1 
ATOM   3464 C  CA   . LEU A 1 245 ? -33.336 3.977   69.82  1   37.672  ? 234 LEU A CA   1 
ATOM   3465 C  C    . LEU A 1 245 ? -31.999 3.284   70.019 1   40.318  ? 234 LEU A C    1 
ATOM   3466 O  O    . LEU A 1 245 ? -31.617 2.376   69.27  1   33.848  ? 234 LEU A O    1 
ATOM   3467 C  CB   . LEU A 1 245 ? -34.465 3.119   70.355 1   38.419  ? 234 LEU A CB   1 
ATOM   3468 C  CG   . LEU A 1 245 ? -35.863 3.769   70.238 1   41.046  ? 234 LEU A CG   1 
ATOM   3469 C  CD1  . LEU A 1 245 ? -36.808 2.596   70.483 1   37.659  ? 234 LEU A CD1  1 
ATOM   3470 C  CD2  . LEU A 1 245 ? -36.116 4.989   71.17  1   39.803  ? 234 LEU A CD2  1 
ATOM   3471 H  H    . LEU A 1 245 ? -34.146 3.777   67.946 1   37.409  ? 234 LEU A H    1 
ATOM   3472 H  HA   . LEU A 1 245 ? -33.323 4.832   70.321 1   38.298  ? 234 LEU A HA   1 
ATOM   3473 H  HB2  . LEU A 1 245 ? -34.469 2.269   69.858 1   38.807  ? 234 LEU A HB2  1 
ATOM   3474 H  HB3  . LEU A 1 245 ? -34.286 2.927   71.305 1   38.822  ? 234 LEU A HB3  1 
ATOM   3475 H  HG   . LEU A 1 245 ? -35.988 4.07    69.301 1   39.655  ? 234 LEU A HG   1 
ATOM   3476 H  HD11 . LEU A 1 245 ? -36.702 1.938   69.775 1   38.653  ? 234 LEU A HD11 1 
ATOM   3477 H  HD12 . LEU A 1 245 ? -37.725 2.915   70.491 1   38.745  ? 234 LEU A HD12 1 
ATOM   3478 H  HD13 . LEU A 1 245 ? -36.601 2.185   71.339 1   38.652  ? 234 LEU A HD13 1 
ATOM   3479 H  HD21 . LEU A 1 245 ? -35.654 5.769   70.817 1   40.158  ? 234 LEU A HD21 1 
ATOM   3480 H  HD22 . LEU A 1 245 ? -35.781 4.792   72.06  1   40.157  ? 234 LEU A HD22 1 
ATOM   3481 H  HD23 . LEU A 1 245 ? -37.069 5.172   71.216 1   40.158  ? 234 LEU A HD23 1 
ATOM   3482 N  N    . ALA A 1 246 ? -31.324 3.718   71.088 1   33.077  ? 235 ALA A N    1 
ATOM   3483 C  CA   . ALA A 1 246 ? -30.109 3.049   71.493 1   32.857  ? 235 ALA A CA   1 
ATOM   3484 C  C    . ALA A 1 246 ? -30.489 1.598   71.707 1   35.81   ? 235 ALA A C    1 
ATOM   3485 O  O    . ALA A 1 246 ? -31.599 1.278   72.163 1   32.014  ? 235 ALA A O    1 
ATOM   3486 C  CB   . ALA A 1 246 ? -29.536 3.709   72.707 1   34.987  ? 235 ALA A CB   1 
ATOM   3487 H  H    . ALA A 1 246 ? -31.624 4.435   71.568 1   34.681  ? 235 ALA A H    1 
ATOM   3488 H  HA   . ALA A 1 246 ? -29.454 3.103   70.743 1   33.769  ? 235 ALA A HA   1 
ATOM   3489 H  HB1  . ALA A 1 246 ? -29.264 4.616   72.489 1   34.332  ? 235 ALA A HB1  1 
ATOM   3490 H  HB2  . ALA A 1 246 ? -30.205 3.734   73.412 1   34.332  ? 235 ALA A HB2  1 
ATOM   3491 H  HB3  . ALA A 1 246 ? -28.763 3.208   73.018 1   34.323  ? 235 ALA A HB3  1 
ATOM   3492 N  N    . GLY A 1 247 ? -29.614 0.728   71.213 1   30.544  ? 236 GLY A N    1 
ATOM   3493 C  CA   . GLY A 1 247 ? -29.812 -0.704  71.321 1   28.474  ? 236 GLY A CA   1 
ATOM   3494 C  C    . GLY A 1 247 ? -30.321 -1.314  70.02  1   31.873  ? 236 GLY A C    1 
ATOM   3495 O  O    . GLY A 1 247 ? -30.296 -2.503  69.866 1   35.877  ? 236 GLY A O    1 
ATOM   3496 H  H    . GLY A 1 247 ? -28.862 1.035   70.795 1   31.259  ? 236 GLY A H    1 
ATOM   3497 H  HA2  . GLY A 1 247 ? -28.956 -1.127  71.565 1   29.714  ? 236 GLY A HA2  1 
ATOM   3498 H  HA3  . GLY A 1 247 ? -30.454 -0.893  72.042 1   29.741  ? 236 GLY A HA3  1 
ATOM   3499 N  N    . ALA A 1 248 ? -30.841 -0.527  69.11  1   34.258  ? 237 ALA A N    1 
ATOM   3500 C  CA   . ALA A 1 248 ? -31.38  -1.095  67.893 1   30.477  ? 237 ALA A CA   1 
ATOM   3501 C  C    . ALA A 1 248 ? -30.287 -1.797  67.108 1   41.074  ? 237 ALA A C    1 
ATOM   3502 O  O    . ALA A 1 248 ? -29.137 -1.362  67.093 1   38.107  ? 237 ALA A O    1 
ATOM   3503 C  CB   . ALA A 1 248 ? -31.916 0.035   67.083 1   33.019  ? 237 ALA A CB   1 
ATOM   3504 H  H    . ALA A 1 248 ? -30.868 0.378   69.235 1   32.764  ? 237 ALA A H    1 
ATOM   3505 H  HA   . ALA A 1 248 ? -32.105 -1.743  68.117 1   33.456  ? 237 ALA A HA   1 
ATOM   3506 H  HB1  . ALA A 1 248 ? -32.591 0.513   67.594 1   32.259  ? 237 ALA A HB1  1 
ATOM   3507 H  HB2  . ALA A 1 248 ? -31.196 0.645   66.854 1   32.286  ? 237 ALA A HB2  1 
ATOM   3508 H  HB3  . ALA A 1 248 ? -32.317 -0.308  66.268 1   32.257  ? 237 ALA A HB3  1 
ATOM   3509 N  N    . GLY A 1 249 ? -30.727 -2.764  66.318 1   35.064  ? 238 GLY A N    1 
ATOM   3510 C  CA   . GLY A 1 249 ? -29.853 -3.631  65.604 1   29.949  ? 238 GLY A CA   1 
ATOM   3511 C  C    . GLY A 1 249 ? -30.198 -3.669  64.12  1   37.302  ? 238 GLY A C    1 
ATOM   3512 O  O    . GLY A 1 249 ? -30.754 -2.722  63.591 1   29.864  ? 238 GLY A O    1 
ATOM   3513 H  H    . GLY A 1 249 ? -31.629 -2.88   66.221 1   35.051  ? 238 GLY A H    1 
ATOM   3514 H  HA2  . GLY A 1 249 ? -28.923 -3.326  65.717 1   32.735  ? 238 GLY A HA2  1 
ATOM   3515 H  HA3  . GLY A 1 249 ? -29.923 -4.536  65.983 1   32.667  ? 238 GLY A HA3  1 
ATOM   3516 N  N    . ASP A 1 250 ? -29.782 -4.767  63.458 1   28.712  ? 239 ASP A N    1 
ATOM   3517 C  CA   . ASP A 1 250 ? -29.944 -4.934  62.014 1   35.13   ? 239 ASP A CA   1 
ATOM   3518 C  C    . ASP A 1 250 ? -31.38  -4.684  61.515 1   38.515  ? 239 ASP A C    1 
ATOM   3519 O  O    . ASP A 1 250 ? -31.585 -3.937  60.571 1   40.22   ? 239 ASP A O    1 
ATOM   3520 C  CB   . ASP A 1 250 ? -29.583 -6.389  61.709 1   33.613  ? 239 ASP A CB   1 
ATOM   3521 C  CG   . ASP A 1 250 ? -29.472 -6.765  60.229 1   40.174  ? 239 ASP A CG   1 
ATOM   3522 O  OD1  . ASP A 1 250 ? -28.442 -6.4    59.499 1   36.862  ? 239 ASP A OD1  1 
ATOM   3523 O  OD2  . ASP A 1 250 ? -30.408 -7.403  59.807 1   37.952  ? 239 ASP A OD2  1 
ATOM   3524 H  H    . ASP A 1 250 ? -29.38  -5.437  63.931 1   32.01   ? 239 ASP A H    1 
ATOM   3525 H  HA   . ASP A 1 250 ? -29.324 -4.328  61.55  1   34.065  ? 239 ASP A HA   1 
ATOM   3526 H  HB2  . ASP A 1 250 ? -28.713 -6.579  62.119 1   35.323  ? 239 ASP A HB2  1 
ATOM   3527 H  HB3  . ASP A 1 250 ? -30.24  -6.982  62.129 1   35.434  ? 239 ASP A HB3  1 
ATOM   3528 N  N    . ASP A 1 251 ? -32.373 -5.435  62.043 1   39.797  ? 240 ASP A N    1 
ATOM   3529 C  CA   . ASP A 1 251 ? -33.773 -5.211  61.638 1   38.655  ? 240 ASP A CA   1 
ATOM   3530 C  C    . ASP A 1 251 ? -34.178 -3.72   61.645 1   34.121  ? 240 ASP A C    1 
ATOM   3531 O  O    . ASP A 1 251 ? -34.633 -3.19   60.645 1   33.613  ? 240 ASP A O    1 
ATOM   3532 C  CB   . ASP A 1 251 ? -34.758 -5.853  62.575 1   37.428  ? 240 ASP A CB   1 
ATOM   3533 C  CG   . ASP A 1 251 ? -36.213 -5.755  62.119 1   44.017  ? 240 ASP A CG   1 
ATOM   3534 O  OD1  . ASP A 1 251 ? -36.519 -6.434  61.116 1   40.851  ? 240 ASP A OD1  1 
ATOM   3535 O  OD2  . ASP A 1 251 ? -36.991 -5.019  62.757 1   38.165  ? 240 ASP A OD2  1 
ATOM   3536 H  H    . ASP A 1 251 ? -32.184 -6.08   62.662 1   39.125  ? 240 ASP A H    1 
ATOM   3537 H  HA   . ASP A 1 251 ? -33.902 -5.576  60.733 1   37.779  ? 240 ASP A HA   1 
ATOM   3538 H  HB2  . ASP A 1 251 ? -34.531 -6.802  62.665 1   39.1    ? 240 ASP A HB2  1 
ATOM   3539 H  HB3  . ASP A 1 251 ? -34.682 -5.441  63.461 1   38.981  ? 240 ASP A HB3  1 
ATOM   3540 N  N    . SER A 1 252 ? -33.911 -2.994  62.735 1   30.199  ? 241 SER A N    1 
ATOM   3541 C  CA   . SER A 1 252 ? -34.299 -1.608  62.79  1   29.956  ? 241 SER A CA   1 
ATOM   3542 C  C    . SER A 1 252 ? -33.659 -0.715  61.764 1   32.76   ? 241 SER A C    1 
ATOM   3543 O  O    . SER A 1 252 ? -34.342 0.135   61.248 1   35.343  ? 241 SER A O    1 
ATOM   3544 C  CB   . SER A 1 252 ? -34.105 -1.083  64.145 1   33.943  ? 241 SER A CB   1 
ATOM   3545 O  OG   . SER A 1 252 ? -34.566 -2.047  65.085 1   31.797  ? 241 SER A OG   1 
ATOM   3546 H  H    . SER A 1 252 ? -33.482 -3.372  63.448 1   31.194  ? 241 SER A H    1 
ATOM   3547 H  HA   . SER A 1 252 ? -35.275 -1.584  62.614 1   31.296  ? 241 SER A HA   1 
ATOM   3548 H  HB2  . SER A 1 252 ? -33.158 -0.904  64.294 1   32.478  ? 241 SER A HB2  1 
ATOM   3549 H  HB3  . SER A 1 252 ? -34.601 -0.252  64.247 1   32.533  ? 241 SER A HB3  1 
ATOM   3550 H  HG   . SER A 1 252 ? -34.454 -1.735  65.856 0   31.57   ? 241 SER A HG   1 
ATOM   3551 N  N    . TRP A 1 253 ? -32.334 -0.805  61.549 1   34.125  ? 242 TRP A N    1 
ATOM   3552 C  CA   . TRP A 1 253 ? -31.655 0.093   60.649 1   34.45   ? 242 TRP A CA   1 
ATOM   3553 C  C    . TRP A 1 253 ? -32.128 -0.156  59.226 1   32.16   ? 242 TRP A C    1 
ATOM   3554 O  O    . TRP A 1 253 ? -32.267 0.77    58.426 1   33.096  ? 242 TRP A O    1 
ATOM   3555 C  CB   . TRP A 1 253 ? -30.101 -0.016  60.751 1   35.872  ? 242 TRP A CB   1 
ATOM   3556 C  CG   . TRP A 1 253 ? -29.605 0.717   61.948 1   32.539  ? 242 TRP A CG   1 
ATOM   3557 C  CD1  . TRP A 1 253 ? -29.774 0.365   63.264 1   30.002  ? 242 TRP A CD1  1 
ATOM   3558 C  CD2  . TRP A 1 253 ? -28.912 1.97    61.942 1   31.43   ? 242 TRP A CD2  1 
ATOM   3559 N  NE1  . TRP A 1 253 ? -29.286 1.365   64.072 1   33.898  ? 242 TRP A NE1  1 
ATOM   3560 C  CE2  . TRP A 1 253 ? -28.727 2.333   63.293 1   31.48   ? 242 TRP A CE2  1 
ATOM   3561 C  CE3  . TRP A 1 253 ? -28.402 2.781   60.934 1   34.383  ? 242 TRP A CE3  1 
ATOM   3562 C  CZ2  . TRP A 1 253 ? -28.077 3.503   63.665 1   37.144  ? 242 TRP A CZ2  1 
ATOM   3563 C  CZ3  . TRP A 1 253 ? -27.671 3.883   61.306 1   32.891  ? 242 TRP A CZ3  1 
ATOM   3564 C  CH2  . TRP A 1 253 ? -27.579 4.271   62.644 1   35.397  ? 242 TRP A CH2  1 
ATOM   3565 H  H    . TRP A 1 253 ? -31.85  -1.447  61.983 1   33.838  ? 242 TRP A H    1 
ATOM   3566 H  HA   . TRP A 1 253 ? -31.909 1.023   60.899 1   34.188  ? 242 TRP A HA   1 
ATOM   3567 H  HB2  . TRP A 1 253 ? -29.851 -0.962  60.823 1   34.742  ? 242 TRP A HB2  1 
ATOM   3568 H  HB3  . TRP A 1 253 ? -29.7   0.371   59.944 1   34.735  ? 242 TRP A HB3  1 
ATOM   3569 H  HD1  . TRP A 1 253 ? -30.261 -0.378  63.575 1   31.459  ? 242 TRP A HD1  1 
ATOM   3570 H  HE1  . TRP A 1 253 ? -29.281 1.351   64.944 1   32.4    ? 242 TRP A HE1  1 
ATOM   3571 H  HE3  . TRP A 1 253 ? -28.478 2.532   60.029 1   33.355  ? 242 TRP A HE3  1 
ATOM   3572 H  HZ2  . TRP A 1 253 ? -27.952 3.735   64.569 1   35.298  ? 242 TRP A HZ2  1 
ATOM   3573 H  HZ3  . TRP A 1 253 ? -27.365 4.475   60.638 1   33.808  ? 242 TRP A HZ3  1 
ATOM   3574 H  HH2  . TRP A 1 253 ? -27.112 5.06    62.857 1   35.146  ? 242 TRP A HH2  1 
ATOM   3575 N  N    . ARG A 1 254 ? -32.227 -1.413  58.855 1   31.25   ? 243 ARG A N    1 
ATOM   3576 C  CA   . ARG A 1 254 ? -32.645 -1.742  57.489 1   36.315  ? 243 ARG A CA   1 
ATOM   3577 C  C    . ARG A 1 254 ? -34.121 -1.341  57.226 1   35.42   ? 243 ARG A C    1 
ATOM   3578 O  O    . ARG A 1 254 ? -34.437 -0.863  56.16  1   35.654  ? 243 ARG A O    1 
ATOM   3579 C  CB   . ARG A 1 254 ? -32.441 -3.249  57.294 1   38.017  ? 243 ARG A CB   1 
ATOM   3580 C  CG   . ARG A 1 254 ? -30.959 -3.589  57.187 1   39.095  ? 243 ARG A CG   1 
ATOM   3581 C  CD   . ARG A 1 254 ? -30.843 -5.104  57.359 1   40.898  ? 243 ARG A CD   1 
ATOM   3582 N  NE   . ARG A 1 254 ? -31.425 -5.833  56.227 1   48.552  ? 243 ARG A NE   1 
ATOM   3583 C  CZ   . ARG A 1 254 ? -31.698 -7.139  56.204 1   49.071  ? 243 ARG A CZ   1 
ATOM   3584 N  NH1  . ARG A 1 254 ? -31.5   -7.923  57.23  1   39.033  ? 243 ARG A NH1  1 
ATOM   3585 N  NH2  . ARG A 1 254 ? -32.165 -7.675  55.111 1   49.856  ? 243 ARG A NH2  1 
ATOM   3586 H  H    . ARG A 1 254 ? -32.03  -2.087  59.441 1   32.634  ? 243 ARG A H    1 
ATOM   3587 H  HA   . ARG A 1 254 ? -32.061 -1.253  56.855 1   35.375  ? 243 ARG A HA   1 
ATOM   3588 H  HB2  . ARG A 1 254 ? -32.835 -3.733  58.051 1   37.88   ? 243 ARG A HB2  1 
ATOM   3589 H  HB3  . ARG A 1 254 ? -32.899 -3.537  56.475 1   37.901  ? 243 ARG A HB3  1 
ATOM   3590 H  HG2  . ARG A 1 254 ? -30.613 -3.326  56.307 1   39.238  ? 243 ARG A HG2  1 
ATOM   3591 H  HG3  . ARG A 1 254 ? -30.453 -3.134  57.895 1   39.2    ? 243 ARG A HG3  1 
ATOM   3592 H  HD2  . ARG A 1 254 ? -29.897 -5.343  57.443 1   42.154  ? 243 ARG A HD2  1 
ATOM   3593 H  HD3  . ARG A 1 254 ? -31.295 -5.374  58.184 1   42.097  ? 243 ARG A HD3  1 
ATOM   3594 H  HE   . ARG A 1 254 ? -31.609 -5.376  55.509 1   46.714  ? 243 ARG A HE   1 
ATOM   3595 H  HH11 . ARG A 1 254 ? -30.715 -7.928  57.635 1   41.895  ? 243 ARG A HH11 1 
ATOM   3596 H  HH12 . ARG A 1 254 ? -32.153 -8.448  57.512 1   41.944  ? 243 ARG A HH12 1 
ATOM   3597 H  HH21 . ARG A 1 254 ? -32.039 -7.274  54.332 1   49.542  ? 243 ARG A HH21 1 
ATOM   3598 H  HH22 . ARG A 1 254 ? -32.606 -8.442  55.152 1   49.446  ? 243 ARG A HH22 1 
ATOM   3599 N  N    . TYR A 1 255 ? -34.986 -1.417  58.222 1   34.217  ? 244 TYR A N    1 
ATOM   3600 C  CA   . TYR A 1 255 ? -36.374 -0.992  58.123 1   35.755  ? 244 TYR A CA   1 
ATOM   3601 C  C    . TYR A 1 255 ? -36.427 0.522   58.028 1   42.221  ? 244 TYR A C    1 
ATOM   3602 O  O    . TYR A 1 255 ? -37.152 1.024   57.187 1   47.016  ? 244 TYR A O    1 
ATOM   3603 C  CB   . TYR A 1 255 ? -37.236 -1.484  59.295 1   35.713  ? 244 TYR A CB   1 
ATOM   3604 C  CG   . TYR A 1 255 ? -38.752 -1.254  59.225 1   44.262  ? 244 TYR A CG   1 
ATOM   3605 C  CD1  . TYR A 1 255 ? -39.573 -2.042  58.413 1   52.236  ? 244 TYR A CD1  1 
ATOM   3606 C  CD2  . TYR A 1 255 ? -39.359 -0.216  59.927 1   46.088  ? 244 TYR A CD2  1 
ATOM   3607 C  CE1  . TYR A 1 255 ? -40.95  -1.845  58.364 1   48.766  ? 244 TYR A CE1  1 
ATOM   3608 C  CE2  . TYR A 1 255 ? -40.717 0.031   59.833 1   52.926  ? 244 TYR A CE2  1 
ATOM   3609 C  CZ   . TYR A 1 255 ? -41.52  -0.804  59.074 1   53.576  ? 244 TYR A CZ   1 
ATOM   3610 O  OH   . TYR A 1 255 ? -42.874 -0.586  59.084 1   50.417  ? 244 TYR A OH   1 
ATOM   3611 H  H    . TYR A 1 255 ? -34.7   -1.761  59.019 1   34.834  ? 244 TYR A H    1 
ATOM   3612 H  HA   . TYR A 1 255 ? -36.752 -1.369  57.284 1   36.592  ? 244 TYR A HA   1 
ATOM   3613 H  HB2  . TYR A 1 255 ? -37.078 -2.449  59.399 1   37.514  ? 244 TYR A HB2  1 
ATOM   3614 H  HB3  . TYR A 1 255 ? -36.9   -1.057  60.114 1   37.514  ? 244 TYR A HB3  1 
ATOM   3615 H  HD1  . TYR A 1 255 ? -39.195 -2.766  57.94  1   49.401  ? 244 TYR A HD1  1 
ATOM   3616 H  HD2  . TYR A 1 255 ? -38.825 0.356   60.455 1   47.103  ? 244 TYR A HD2  1 
ATOM   3617 H  HE1  . TYR A 1 255 ? -41.49  -2.407  57.836 1   50.554  ? 244 TYR A HE1  1 
ATOM   3618 H  HE2  . TYR A 1 255 ? -41.109 0.713   60.352 1   51.272  ? 244 TYR A HE2  1 
ATOM   3619 H  HH   . TYR A 1 255 ? -43.24  -1.03   59.722 0   50.71   ? 244 TYR A HH   1 
ATOM   3620 N  N    . ALA A 1 256 ? -35.581 1.27    58.755 1   43.991  ? 245 ALA A N    1 
ATOM   3621 C  CA   . ALA A 1 256 ? -35.597 2.722   58.595 1   36.229  ? 245 ALA A CA   1 
ATOM   3622 C  C    . ALA A 1 256 ? -35.236 3.111   57.177 1   38.849  ? 245 ALA A C    1 
ATOM   3623 O  O    . ALA A 1 256 ? -35.746 4.069   56.589 1   40.547  ? 245 ALA A O    1 
ATOM   3624 C  CB   . ALA A 1 256 ? -34.657 3.371   59.545 1   39.835  ? 245 ALA A CB   1 
ATOM   3625 H  H    . ALA A 1 256 ? -35.003 0.883   59.349 1   41.648  ? 245 ALA A H    1 
ATOM   3626 H  HA   . ALA A 1 256 ? -36.521 3.046   58.78  1   38.826  ? 245 ALA A HA   1 
ATOM   3627 H  HB1  . ALA A 1 256 ? -34.897 3.133   60.457 1   38.712  ? 245 ALA A HB1  1 
ATOM   3628 H  HB2  . ALA A 1 256 ? -33.75  3.071   59.364 1   38.713  ? 245 ALA A HB2  1 
ATOM   3629 H  HB3  . ALA A 1 256 ? -34.702 4.337   59.443 1   38.713  ? 245 ALA A HB3  1 
ATOM   3630 N  N    . LEU A 1 257 ? -34.307 2.375   56.63  1   43.948  ? 246 LEU A N    1 
ATOM   3631 C  CA   . LEU A 1 257 ? -33.866 2.665   55.277 1   52.069  ? 246 LEU A CA   1 
ATOM   3632 C  C    . LEU A 1 257 ? -34.966 2.343   54.261 1   47.677  ? 246 LEU A C    1 
ATOM   3633 O  O    . LEU A 1 257 ? -35.145 3.143   53.349 1   45.793  ? 246 LEU A O    1 
ATOM   3634 C  CB   . LEU A 1 257 ? -32.583 1.875   55.038 1   48.843  ? 246 LEU A CB   1 
ATOM   3635 C  CG   . LEU A 1 257 ? -31.496 2.427   54.107 1   59.084  ? 246 LEU A CG   1 
ATOM   3636 C  CD1  . LEU A 1 257 ? -30.863 3.671   54.555 1   57.666  ? 246 LEU A CD1  1 
ATOM   3637 C  CD2  . LEU A 1 257 ? -30.373 1.398   53.962 1   62.997  ? 246 LEU A CD2  1 
ATOM   3638 H  H    . LEU A 1 257 ? -33.931 1.681   57.09  1   44.346  ? 246 LEU A H    1 
ATOM   3639 H  HA   . LEU A 1 257 ? -33.661 3.633   55.219 1   48.917  ? 246 LEU A HA   1 
ATOM   3640 H  HB2  . LEU A 1 257 ? -32.165 1.713   55.915 1   51.55   ? 246 LEU A HB2  1 
ATOM   3641 H  HB3  . LEU A 1 257 ? -32.839 0.984   54.707 1   51.84   ? 246 LEU A HB3  1 
ATOM   3642 H  HG   . LEU A 1 257 ? -31.897 2.582   53.213 1   57.466  ? 246 LEU A HG   1 
ATOM   3643 H  HD11 . LEU A 1 257 ? -31.533 4.37    54.624 1   57.797  ? 246 LEU A HD11 1 
ATOM   3644 H  HD12 . LEU A 1 257 ? -30.183 3.94    53.914 1   58.083  ? 246 LEU A HD12 1 
ATOM   3645 H  HD13 . LEU A 1 257 ? -30.45  3.532   55.424 1   58.082  ? 246 LEU A HD13 1 
ATOM   3646 H  HD21 . LEU A 1 257 ? -30.745 0.548   53.674 1   61.725  ? 246 LEU A HD21 1 
ATOM   3647 H  HD22 . LEU A 1 257 ? -29.927 1.28    54.818 1   61.741  ? 246 LEU A HD22 1 
ATOM   3648 H  HD23 . LEU A 1 257 ? -29.729 1.708   53.303 1   61.742  ? 246 LEU A HD23 1 
ATOM   3649 N  N    . GLU A 1 258 ? -35.618 1.161   54.368 1   51.239  ? 247 GLU A N    1 
ATOM   3650 C  CA   . GLU A 1 258 ? -36.647 0.694   53.422 1   57.331  ? 247 GLU A CA   1 
ATOM   3651 C  C    . GLU A 1 258 ? -37.827 1.67    53.478 1   47.411  ? 247 GLU A C    1 
ATOM   3652 O  O    . GLU A 1 258 ? -38.291 2.161   52.47  1   52.421  ? 247 GLU A O    1 
ATOM   3653 C  CB   . GLU A 1 258 ? -37.247 -0.7    53.681 1   59.453  ? 247 GLU A CB   1 
ATOM   3654 C  CG   . GLU A 1 258 ? -36.432 -1.914  53.22  1   87.92   ? 247 GLU A CG   1 
ATOM   3655 C  CD   . GLU A 1 258 ? -36.45  -3.246  54.029 1   107.81  ? 247 GLU A CD   1 
ATOM   3656 O  OE1  . GLU A 1 258 ? -35.531 -4.101  53.763 1   86.178  ? 247 GLU A OE1  1 
ATOM   3657 O  OE2  . GLU A 1 258 ? -37.313 -3.462  54.944 1   74.207  ? 247 GLU A OE2  1 
ATOM   3658 H  H    . GLU A 1 258 ? -35.406 0.616   55.07  1   51.599  ? 247 GLU A H    1 
ATOM   3659 H  HA   . GLU A 1 258 ? -36.262 0.714   52.509 1   54.538  ? 247 GLU A HA   1 
ATOM   3660 H  HB2  . GLU A 1 258 ? -37.401 -0.793  54.644 1   64.588  ? 247 GLU A HB2  1 
ATOM   3661 H  HB3  . GLU A 1 258 ? -38.12  -0.749  53.238 1   64.467  ? 247 GLU A HB3  1 
ATOM   3662 H  HG2  . GLU A 1 258 ? -36.713 -2.129  52.305 1   84.056  ? 247 GLU A HG2  1 
ATOM   3663 H  HG3  . GLU A 1 258 ? -35.496 -1.633  53.15  1   83.977  ? 247 GLU A HG3  1 
ATOM   3664 N  N    . THR A 1 259 ? -38.204 2.043   54.694 1   50.207  ? 248 THR A N    1 
ATOM   3665 C  CA   . THR A 1 259 ? -39.443 2.73    54.989 1   44.442  ? 248 THR A CA   1 
ATOM   3666 C  C    . THR A 1 259 ? -39.292 4.252   54.877 1   48.116  ? 248 THR A C    1 
ATOM   3667 O  O    . THR A 1 259 ? -40.292 4.946   54.713 1   45.835  ? 248 THR A O    1 
ATOM   3668 C  CB   . THR A 1 259 ? -39.861 2.315   56.398 1   40.609  ? 248 THR A CB   1 
ATOM   3669 O  OG1  . THR A 1 259 ? -40.188 0.934   56.431 1   52.186  ? 248 THR A OG1  1 
ATOM   3670 C  CG2  . THR A 1 259 ? -41.136 2.994   56.874 1   50.062  ? 248 THR A CG2  1 
ATOM   3671 H  H    . THR A 1 259 ? -37.646 1.854   55.392 1   48.164  ? 248 THR A H    1 
ATOM   3672 H  HA   . THR A 1 259 ? -40.129 2.429   54.354 1   45.462  ? 248 THR A HA   1 
ATOM   3673 H  HB   . THR A 1 259 ? -39.135 2.502   57.04  1   45.082  ? 248 THR A HB   1 
ATOM   3674 H  HG1  . THR A 1 259 ? -40.835 0.761   55.884 0   52.23   ? 248 THR A HG1  1 
ATOM   3675 H  HG21 . THR A 1 259 ? -41.502 2.506   57.63  1   47.091  ? 248 THR A HG21 1 
ATOM   3676 H  HG22 . THR A 1 259 ? -41.786 3.006   56.152 1   47.065  ? 248 THR A HG22 1 
ATOM   3677 H  HG23 . THR A 1 259 ? -40.937 3.906   57.145 1   47.065  ? 248 THR A HG23 1 
ATOM   3678 N  N    . ILE A 1 260 ? -38.099 4.841   55.068 1   40.456  ? 249 ILE A N    1 
ATOM   3679 C  CA   . ILE A 1 260 ? -37.999 6.315   55.073 1   34.509  ? 249 ILE A CA   1 
ATOM   3680 C  C    . ILE A 1 260 ? -37.076 6.798   53.981 1   43.688  ? 249 ILE A C    1 
ATOM   3681 O  O    . ILE A 1 260 ? -37.445 7.673   53.199 1   43.214  ? 249 ILE A O    1 
ATOM   3682 C  CB   . ILE A 1 260 ? -37.659 6.937   56.445 1   36.141  ? 249 ILE A CB   1 
ATOM   3683 C  CG1  . ILE A 1 260 ? -38.764 6.704   57.487 1   41.303  ? 249 ILE A CG1  1 
ATOM   3684 C  CG2  . ILE A 1 260 ? -37.387 8.423   56.252 1   31.783  ? 249 ILE A CG2  1 
ATOM   3685 C  CD1  . ILE A 1 260 ? -38.444 6.967   58.954 1   42.415  ? 249 ILE A CD1  1 
ATOM   3686 H  H    . ILE A 1 260 ? -37.35  4.337   55.209 1   40.832  ? 249 ILE A H    1 
ATOM   3687 H  HA   . ILE A 1 260 ? -38.886 6.651   54.843 1   37.676  ? 249 ILE A HA   1 
ATOM   3688 H  HB   . ILE A 1 260 ? -36.84  6.516   56.774 1   35.884  ? 249 ILE A HB   1 
ATOM   3689 H  HG12 . ILE A 1 260 ? -39.526 7.268   57.242 1   40.345  ? 249 ILE A HG12 1 
ATOM   3690 H  HG13 . ILE A 1 260 ? -39.06  5.774   57.407 1   40.318  ? 249 ILE A HG13 1 
ATOM   3691 H  HG21 . ILE A 1 260 ? -37.443 8.878   57.109 1   33.174  ? 249 ILE A HG21 1 
ATOM   3692 H  HG22 . ILE A 1 260 ? -38.046 8.801   55.646 1   33.109  ? 249 ILE A HG22 1 
ATOM   3693 H  HG23 . ILE A 1 260 ? -36.497 8.548   55.882 1   33.107  ? 249 ILE A HG23 1 
ATOM   3694 H  HD11 . ILE A 1 260 ? -37.677 6.426   59.223 1   42.067  ? 249 ILE A HD11 1 
ATOM   3695 H  HD12 . ILE A 1 260 ? -39.215 6.73    59.503 1   42.066  ? 249 ILE A HD12 1 
ATOM   3696 H  HD13 . ILE A 1 260 ? -38.234 7.911   59.081 1   42.013  ? 249 ILE A HD13 1 
ATOM   3697 N  N    . VAL A 1 261 ? -35.856 6.228   53.947 1   45.95   ? 250 VAL A N    1 
ATOM   3698 C  CA   . VAL A 1 261 ? -34.831 6.793   53.114 1   37.377  ? 250 VAL A CA   1 
ATOM   3699 C  C    . VAL A 1 261 ? -35.094 6.512   51.652 1   37.493  ? 250 VAL A C    1 
ATOM   3700 O  O    . VAL A 1 261 ? -34.907 7.435   50.858 1   36.392  ? 250 VAL A O    1 
ATOM   3701 C  CB   . VAL A 1 261 ? -33.453 6.243   53.524 1   49.68   ? 250 VAL A CB   1 
ATOM   3702 C  CG1  . VAL A 1 261 ? -32.345 6.706   52.58  1   41.949  ? 250 VAL A CG1  1 
ATOM   3703 C  CG2  . VAL A 1 261 ? -33.151 6.621   54.95  1   41.522  ? 250 VAL A CG2  1 
ATOM   3704 H  H    . VAL A 1 261 ? -35.672 5.486   54.448 1   43.254  ? 250 VAL A H    1 
ATOM   3705 H  HA   . VAL A 1 261 ? -34.827 7.762   53.247 1   41.02   ? 250 VAL A HA   1 
ATOM   3706 H  HB   . VAL A 1 261 ? -33.504 5.26    53.474 1   44.188  ? 250 VAL A HB   1 
ATOM   3707 H  HG11 . VAL A 1 261 ? -32.462 7.649   52.379 1   44.088  ? 250 VAL A HG11 1 
ATOM   3708 H  HG12 . VAL A 1 261 ? -32.382 6.192   51.756 1   44.059  ? 250 VAL A HG12 1 
ATOM   3709 H  HG13 . VAL A 1 261 ? -31.479 6.571   53.003 1   44.107  ? 250 VAL A HG13 1 
ATOM   3710 H  HG21 . VAL A 1 261 ? -32.199 6.528   55.12  1   43.861  ? 250 VAL A HG21 1 
ATOM   3711 H  HG22 . VAL A 1 261 ? -33.644 6.038   55.551 1   43.807  ? 250 VAL A HG22 1 
ATOM   3712 H  HG23 . VAL A 1 261 ? -33.418 7.543   55.105 1   43.728  ? 250 VAL A HG23 1 
ATOM   3713 N  N    . ILE A 1 262 ? -35.356 5.253   51.268 1   35.008  ? 251 ILE A N    1 
ATOM   3714 C  CA   . ILE A 1 262 ? -35.515 4.989   49.833 1   46.801  ? 251 ILE A CA   1 
ATOM   3715 C  C    . ILE A 1 262 ? -36.7   5.792   49.275 1   57.487  ? 251 ILE A C    1 
ATOM   3716 O  O    . ILE A 1 262 ? -36.616 6.319   48.166 1   55.971  ? 251 ILE A O    1 
ATOM   3717 C  CB   . ILE A 1 262 ? -35.698 3.495   49.487 1   55.691  ? 251 ILE A CB   1 
ATOM   3718 C  CG1  . ILE A 1 262 ? -34.574 2.662   49.976 1   52.632  ? 251 ILE A CG1  1 
ATOM   3719 C  CG2  . ILE A 1 262 ? -35.877 3.298   47.984 1   74.008  ? 251 ILE A CG2  1 
ATOM   3720 C  CD1  . ILE A 1 262 ? -33.208 3.262   49.754 1   58.007  ? 251 ILE A CD1  1 
ATOM   3721 H  H    . ILE A 1 262 ? -35.436 4.574   51.875 1   38.17   ? 251 ILE A H    1 
ATOM   3722 H  HA   . ILE A 1 262 ? -34.708 5.302   49.382 1   47.428  ? 251 ILE A HA   1 
ATOM   3723 H  HB   . ILE A 1 262 ? -36.506 3.179   49.926 1   56.205  ? 251 ILE A HB   1 
ATOM   3724 H  HG12 . ILE A 1 262 ? -34.694 2.508   50.935 1   54.389  ? 251 ILE A HG12 1 
ATOM   3725 H  HG13 . ILE A 1 262 ? -34.609 1.791   49.531 1   54.685  ? 251 ILE A HG13 1 
ATOM   3726 H  HG21 . ILE A 1 262 ? -35.788 2.355   47.765 1   67.797  ? 251 ILE A HG21 1 
ATOM   3727 H  HG22 . ILE A 1 262 ? -35.2   3.805   47.506 1   67.979  ? 251 ILE A HG22 1 
ATOM   3728 H  HG23 . ILE A 1 262 ? -36.76  3.605   47.717 1   67.934  ? 251 ILE A HG23 1 
ATOM   3729 H  HD11 . ILE A 1 262 ? -33.163 3.657   48.863 1   56.283  ? 251 ILE A HD11 1 
ATOM   3730 H  HD12 . ILE A 1 262 ? -32.532 2.562   49.831 1   56.315  ? 251 ILE A HD12 1 
ATOM   3731 H  HD13 . ILE A 1 262 ? -33.036 3.951   50.424 1   56.228  ? 251 ILE A HD13 1 
ATOM   3732 N  N    . PRO A 1 263 ? -37.875 5.795   49.946 1   47.553  ? 252 PRO A N    1 
ATOM   3733 C  CA   . PRO A 1 263 ? -39.012 6.623   49.521 1   48.333  ? 252 PRO A CA   1 
ATOM   3734 C  C    . PRO A 1 263 ? -38.689 8.102   49.435 1   49.996  ? 252 PRO A C    1 
ATOM   3735 O  O    . PRO A 1 263 ? -39.085 8.778   48.474 1   44.91   ? 252 PRO A O    1 
ATOM   3736 C  CB   . PRO A 1 263 ? -40.089 6.324   50.584 1   53.296  ? 252 PRO A CB   1 
ATOM   3737 C  CG   . PRO A 1 263 ? -39.787 4.871   50.925 1   55.719  ? 252 PRO A CG   1 
ATOM   3738 C  CD   . PRO A 1 263 ? -38.245 4.793   50.951 1   50.356  ? 252 PRO A CD   1 
ATOM   3739 H  HA   . PRO A 1 263 ? -39.326 6.301   48.639 1   49.344  ? 252 PRO A HA   1 
ATOM   3740 H  HB2  . PRO A 1 263 ? -39.985 6.906   51.373 1   52.664  ? 252 PRO A HB2  1 
ATOM   3741 H  HB3  . PRO A 1 263 ? -40.996 6.424   50.212 1   52.676  ? 252 PRO A HB3  1 
ATOM   3742 H  HG2  . PRO A 1 263 ? -40.162 4.632   51.798 1   53.936  ? 252 PRO A HG2  1 
ATOM   3743 H  HG3  . PRO A 1 263 ? -40.155 4.269   50.246 1   53.936  ? 252 PRO A HG3  1 
ATOM   3744 H  HD2  . PRO A 1 263 ? -37.892 5.025   51.838 1   50.676  ? 252 PRO A HD2  1 
ATOM   3745 H  HD3  . PRO A 1 263 ? -37.939 3.9     50.699 1   50.843  ? 252 PRO A HD3  1 
ATOM   3746 N  N    . ALA A 1 264 ? -37.856 8.58    50.376 1   56.543  ? 253 ALA A N    1 
ATOM   3747 C  CA   . ALA A 1 264 ? -37.494 9.993   50.326 1   50.46   ? 253 ALA A CA   1 
ATOM   3748 C  C    . ALA A 1 264 ? -36.583 10.246  49.122 1   48.548  ? 253 ALA A C    1 
ATOM   3749 O  O    . ALA A 1 264 ? -36.57  11.334  48.559 1   52.467  ? 253 ALA A O    1 
ATOM   3750 C  CB   . ALA A 1 264 ? -36.913 10.502  51.609 1   51.214  ? 253 ALA A CB   1 
ATOM   3751 H  H    . ALA A 1 264 ? -37.526 8.046   51.04  1   53.34   ? 253 ALA A H    1 
ATOM   3752 H  HA   . ALA A 1 264 ? -38.336 10.501  50.161 1   51.317  ? 253 ALA A HA   1 
ATOM   3753 H  HB1  . ALA A 1 264 ? -37.557 10.386  52.328 1   50.988  ? 253 ALA A HB1  1 
ATOM   3754 H  HB2  . ALA A 1 264 ? -36.103 10.009  51.82  1   50.988  ? 253 ALA A HB2  1 
ATOM   3755 H  HB3  . ALA A 1 264 ? -36.7   11.446  51.519 1   50.988  ? 253 ALA A HB3  1 
ATOM   3756 N  N    . LEU A 1 265 ? -35.827 9.248   48.683 1   45.134  ? 254 LEU A N    1 
ATOM   3757 C  CA   . LEU A 1 265 ? -34.934 9.505   47.565 1   49.939  ? 254 LEU A CA   1 
ATOM   3758 C  C    . LEU A 1 265 ? -35.781 9.519   46.29  1   50.173  ? 254 LEU A C    1 
ATOM   3759 O  O    . LEU A 1 265 ? -35.566 10.337  45.413 1   46.8    ? 254 LEU A O    1 
ATOM   3760 C  CB   . LEU A 1 265 ? -33.852 8.429   47.476 1   45.46   ? 254 LEU A CB   1 
ATOM   3761 C  CG   . LEU A 1 265 ? -32.785 8.376   48.583 1   47.086  ? 254 LEU A CG   1 
ATOM   3762 C  CD1  . LEU A 1 265 ? -31.97  7.081   48.537 1   45.063  ? 254 LEU A CD1  1 
ATOM   3763 C  CD2  . LEU A 1 265 ? -31.864 9.537   48.436 1   41.331  ? 254 LEU A CD2  1 
ATOM   3764 H  H    . LEU A 1 265 ? -35.846 8.422   49.074 1   47.121  ? 254 LEU A H    1 
ATOM   3765 H  HA   . LEU A 1 265 ? -34.51  10.392  47.687 1   48.136  ? 254 LEU A HA   1 
ATOM   3766 H  HB2  . LEU A 1 265 ? -34.302 7.553   47.443 1   46.847  ? 254 LEU A HB2  1 
ATOM   3767 H  HB3  . LEU A 1 265 ? -33.39  8.536   46.613 1   46.788  ? 254 LEU A HB3  1 
ATOM   3768 H  HG   . LEU A 1 265 ? -33.236 8.44    49.463 1   45.208  ? 254 LEU A HG   1 
ATOM   3769 H  HD11 . LEU A 1 265 ? -32.565 6.327   48.386 1   45.662  ? 254 LEU A HD11 1 
ATOM   3770 H  HD12 . LEU A 1 265 ? -31.506 6.959   49.382 1   45.706  ? 254 LEU A HD12 1 
ATOM   3771 H  HD13 . LEU A 1 265 ? -31.322 7.13    47.816 1   45.622  ? 254 LEU A HD13 1 
ATOM   3772 H  HD21 . LEU A 1 265 ? -32.369 10.364  48.504 1   43.073  ? 254 LEU A HD21 1 
ATOM   3773 H  HD22 . LEU A 1 265 ? -31.426 9.496   47.569 1   43.055  ? 254 LEU A HD22 1 
ATOM   3774 H  HD23 . LEU A 1 265 ? -31.193 9.51    49.138 1   43.065  ? 254 LEU A HD23 1 
ATOM   3775 N  N    . ALA A 1 266 ? -36.678 8.532   46.185 1   52.805  ? 255 ALA A N    1 
ATOM   3776 C  CA   . ALA A 1 266 ? -37.68  8.474   45.123 1   63.255  ? 255 ALA A CA   1 
ATOM   3777 C  C    . ALA A 1 266 ? -38.413 9.813   44.971 1   52.292  ? 255 ALA A C    1 
ATOM   3778 O  O    . ALA A 1 266 ? -38.5   10.27   43.852 1   55.528  ? 255 ALA A O    1 
ATOM   3779 C  CB   . ALA A 1 266 ? -38.64  7.317   45.321 1   54.746  ? 255 ALA A CB   1 
ATOM   3780 H  H    . ALA A 1 266 ? -36.66  7.855   46.799 1   54.239  ? 255 ALA A H    1 
ATOM   3781 H  HA   . ALA A 1 266 ? -37.188 8.314   44.271 1   57.412  ? 255 ALA A HA   1 
ATOM   3782 H  HB1  . ALA A 1 266 ? -38.145 6.481   45.337 1   57.121  ? 255 ALA A HB1  1 
ATOM   3783 H  HB2  . ALA A 1 266 ? -39.114 7.426   46.162 1   57.063  ? 255 ALA A HB2  1 
ATOM   3784 H  HB3  . ALA A 1 266 ? -39.281 7.297   44.591 1   57.121  ? 255 ALA A HB3  1 
ATOM   3785 N  N    . ARG A 1 267 ? -38.851 10.482  46.055 1   53.057  ? 256 ARG A N    1 
ATOM   3786 C  CA   . ARG A 1 267 ? -39.58  11.743  45.927 1   53.864  ? 256 ARG A CA   1 
ATOM   3787 C  C    . ARG A 1 267 ? -38.647 12.825  45.39  1   61.262  ? 256 ARG A C    1 
ATOM   3788 O  O    . ARG A 1 267 ? -39.001 13.546  44.458 1   55.855  ? 256 ARG A O    1 
ATOM   3789 C  CB   . ARG A 1 267 ? -40.25  12.186  47.233 1   65.2    ? 256 ARG A CB   1 
ATOM   3790 C  CG   . ARG A 1 267 ? -41.66  12.731  47.068 1   85.954  ? 256 ARG A CG   1 
ATOM   3791 C  CD   . ARG A 1 267 ? -42.415 12.945  48.384 1   99.851  ? 256 ARG A CD   1 
ATOM   3792 N  NE   . ARG A 1 267 ? -41.518 13.8    49.167 1   106.767 ? 256 ARG A NE   1 
ATOM   3793 C  CZ   . ARG A 1 267 ? -41.212 13.69   50.448 1   94.898  ? 256 ARG A CZ   1 
ATOM   3794 N  NH1  . ARG A 1 267 ? -42.095 13.277  51.345 1   74.602  ? 256 ARG A NH1  1 
ATOM   3795 N  NH2  . ARG A 1 267 ? -40.033 14.133  50.832 1   89.06   ? 256 ARG A NH2  1 
ATOM   3796 H  H    . ARG A 1 267 ? -38.691 10.144  46.889 1   53.222  ? 256 ARG A H    1 
ATOM   3797 H  HA   . ARG A 1 267 ? -40.299 11.606  45.258 1   57.196  ? 256 ARG A HA   1 
ATOM   3798 H  HB2  . ARG A 1 267 ? -40.282 11.42   47.845 1   66.374  ? 256 ARG A HB2  1 
ATOM   3799 H  HB3  . ARG A 1 267 ? -39.692 12.876  47.653 1   66.646  ? 256 ARG A HB3  1 
ATOM   3800 H  HG2  . ARG A 1 267 ? -41.614 13.588  46.59  1   83.521  ? 256 ARG A HG2  1 
ATOM   3801 H  HG3  . ARG A 1 267 ? -42.177 12.112  46.508 1   83.26   ? 256 ARG A HG3  1 
ATOM   3802 H  HD2  . ARG A 1 267 ? -43.27  13.399  48.238 1   98.148  ? 256 ARG A HD2  1 
ATOM   3803 H  HD3  . ARG A 1 267 ? -42.568 12.099  48.853 1   98.134  ? 256 ARG A HD3  1 
ATOM   3804 H  HE   . ARG A 1 267 ? -41.145 14.466  48.746 1   101.606 ? 256 ARG A HE   1 
ATOM   3805 H  HH11 . ARG A 1 267 ? -42.916 13.065  51.093 1   80.617  ? 256 ARG A HH11 1 
ATOM   3806 H  HH12 . ARG A 1 267 ? -41.861 13.218  52.196 1   80.392  ? 256 ARG A HH12 1 
ATOM   3807 H  HH21 . ARG A 1 267 ? -39.336 14.05   50.295 1   90.199  ? 256 ARG A HH21 1 
ATOM   3808 H  HH22 . ARG A 1 267 ? -39.943 14.51   51.626 1   90.468  ? 256 ARG A HH22 1 
ATOM   3809 N  N    . PHE A 1 268 ? -37.402 12.868  45.877 1   56.075  ? 257 PHE A N    1 
ATOM   3810 C  CA   . PHE A 1 268 ? -36.51  13.973  45.546 1   44.92   ? 257 PHE A CA   1 
ATOM   3811 C  C    . PHE A 1 268 ? -35.794 13.846  44.204 1   41.588  ? 257 PHE A C    1 
ATOM   3812 O  O    . PHE A 1 268 ? -35.348 14.841  43.669 1   43.327  ? 257 PHE A O    1 
ATOM   3813 C  CB   . PHE A 1 268 ? -35.527 13.985  46.706 1   52.726  ? 257 PHE A CB   1 
ATOM   3814 C  CG   . PHE A 1 268 ? -34.416 15      46.594 1   45.9    ? 257 PHE A CG   1 
ATOM   3815 C  CD1  . PHE A 1 268 ? -34.63  16.326  46.916 1   52.103  ? 257 PHE A CD1  1 
ATOM   3816 C  CD2  . PHE A 1 268 ? -33.134 14.596  46.255 1   47.326  ? 257 PHE A CD2  1 
ATOM   3817 C  CE1  . PHE A 1 268 ? -33.587 17.249  46.824 1   38.744  ? 257 PHE A CE1  1 
ATOM   3818 C  CE2  . PHE A 1 268 ? -32.109 15.5    46.183 1   48.996  ? 257 PHE A CE2  1 
ATOM   3819 C  CZ   . PHE A 1 268 ? -32.332 16.829  46.475 1   46.587  ? 257 PHE A CZ   1 
ATOM   3820 H  H    . PHE A 1 268 ? -37.102 12.199  46.425 1   54.412  ? 257 PHE A H    1 
ATOM   3821 H  HA   . PHE A 1 268 ? -37.03  14.82   45.557 1   47.723  ? 257 PHE A HA   1 
ATOM   3822 H  HB2  . PHE A 1 268 ? -36.028 14.157  47.534 1   49.247  ? 257 PHE A HB2  1 
ATOM   3823 H  HB3  . PHE A 1 268 ? -35.127 13.09   46.783 1   49.29   ? 257 PHE A HB3  1 
ATOM   3824 H  HD1  . PHE A 1 268 ? -35.495 16.615  47.155 1   47.359  ? 257 PHE A HD1  1 
ATOM   3825 H  HD2  . PHE A 1 268 ? -32.97  13.688  46.055 1   47.397  ? 257 PHE A HD2  1 
ATOM   3826 H  HE1  . PHE A 1 268 ? -33.742 18.156  47.028 1   43.463  ? 257 PHE A HE1  1 
ATOM   3827 H  HE2  . PHE A 1 268 ? -31.246 15.212  45.931 1   47.963  ? 257 PHE A HE2  1 
ATOM   3828 H  HZ   . PHE A 1 268 ? -31.625 17.451  46.417 1   45.206  ? 257 PHE A HZ   1 
ATOM   3829 N  N    . GLU A 1 269 ? -35.611 12.637  43.678 1   44.828  ? 258 GLU A N    1 
ATOM   3830 C  CA   . GLU A 1 269 ? -35.007 12.399  42.359 1   57.24   ? 258 GLU A CA   1 
ATOM   3831 C  C    . GLU A 1 269 ? -33.604 13.029  42.252 1   63.419  ? 258 GLU A C    1 
ATOM   3832 O  O    . GLU A 1 269 ? -33.405 14.035  41.567 1   46.946  ? 258 GLU A O    1 
ATOM   3833 C  CB   . GLU A 1 269 ? -35.966 12.802  41.23  1   60.535  ? 258 GLU A CB   1 
ATOM   3834 C  CG   . GLU A 1 269 ? -37.364 12.17   41.318 1   78.578  ? 258 GLU A CG   1 
ATOM   3835 C  CD   . GLU A 1 269 ? -38.318 12.219  40.106 1   88.449  ? 258 GLU A CD   1 
ATOM   3836 O  OE1  . GLU A 1 269 ? -37.87  12.729  39.064 1   76.165  ? 258 GLU A OE1  1 
ATOM   3837 O  OE2  . GLU A 1 269 ? -39.489 11.735  40.164 1   79.605  ? 258 GLU A OE2  1 
ATOM   3838 H  H    . GLU A 1 269 ? -35.872 11.91   44.166 1   46.579  ? 258 GLU A H    1 
ATOM   3839 H  HA   . GLU A 1 269 ? -34.89  11.419  42.269 1   56.158  ? 258 GLU A HA   1 
ATOM   3840 H  HB2  . GLU A 1 269 ? -36.065 13.777  41.236 1   63.456  ? 258 GLU A HB2  1 
ATOM   3841 H  HB3  . GLU A 1 269 ? -35.563 12.55   40.373 1   63.496  ? 258 GLU A HB3  1 
ATOM   3842 H  HG2  . GLU A 1 269 ? -37.251 11.227  41.561 1   76.003  ? 258 GLU A HG2  1 
ATOM   3843 H  HG3  . GLU A 1 269 ? -37.833 12.586  42.073 1   75.838  ? 258 GLU A HG3  1 
ATOM   3844 N  N    . PRO A 1 270 ? -32.569 12.516  42.965 1   56.489  ? 259 PRO A N    1 
ATOM   3845 C  CA   . PRO A 1 270 ? -31.228 13.137  42.902 1   54.622  ? 259 PRO A CA   1 
ATOM   3846 C  C    . PRO A 1 270 ? -30.451 12.744  41.646 1   46.464  ? 259 PRO A C    1 
ATOM   3847 O  O    . PRO A 1 270 ? -30.773 11.733  41.045 1   42.691  ? 259 PRO A O    1 
ATOM   3848 C  CB   . PRO A 1 270 ? -30.584 12.537  44.144 1   49.895  ? 259 PRO A CB   1 
ATOM   3849 C  CG   . PRO A 1 270 ? -31.16  11.118  44.156 1   51.111  ? 259 PRO A CG   1 
ATOM   3850 C  CD   . PRO A 1 270 ? -32.648 11.386  43.917 1   53.106  ? 259 PRO A CD   1 
ATOM   3851 H  HA   . PRO A 1 270 ? -31.293 14.121  42.987 1   52.469  ? 259 PRO A HA   1 
ATOM   3852 H  HB2  . PRO A 1 270 ? -29.603 12.523  44.066 1   51.122  ? 259 PRO A HB2  1 
ATOM   3853 H  HB3  . PRO A 1 270 ? -30.844 13.034  44.955 1   51.18   ? 259 PRO A HB3  1 
ATOM   3854 H  HG2  . PRO A 1 270 ? -30.776 10.568  43.441 1   51.201  ? 259 PRO A HG2  1 
ATOM   3855 H  HG3  . PRO A 1 270 ? -31.011 10.679  45.02  1   51.26   ? 259 PRO A HG3  1 
ATOM   3856 H  HD2  . PRO A 1 270 ? -33.093 10.606  43.517 1   53.449  ? 259 PRO A HD2  1 
ATOM   3857 H  HD3  . PRO A 1 270 ? -33.105 11.644  44.747 1   53.421  ? 259 PRO A HD3  1 
ATOM   3858 N  N    . GLU A 1 271 ? -29.36  13.468  41.349 1   51.884  ? 260 GLU A N    1 
ATOM   3859 C  CA   . GLU A 1 271 ? -28.408 13.091  40.313 1   55.919  ? 260 GLU A CA   1 
ATOM   3860 C  C    . GLU A 1 271 ? -27.231 12.309  40.888 1   49.441  ? 260 GLU A C    1 
ATOM   3861 O  O    . GLU A 1 271 ? -26.416 11.809  40.114 1   40.851  ? 260 GLU A O    1 
ATOM   3862 C  CB   . GLU A 1 271 ? -27.755 14.288  39.619 1   66.14   ? 260 GLU A CB   1 
ATOM   3863 C  CG   . GLU A 1 271 ? -28.747 15.166  38.854 1   74.134  ? 260 GLU A CG   1 
ATOM   3864 C  CD   . GLU A 1 271 ? -28.171 16.489  38.343 1   82.056  ? 260 GLU A CD   1 
ATOM   3865 O  OE1  . GLU A 1 271 ? -26.92  16.623  38.21  1   74.104  ? 260 GLU A OE1  1 
ATOM   3866 O  OE2  . GLU A 1 271 ? -28.984 17.422  38.134 1   85.185  ? 260 GLU A OE2  1 
ATOM   3867 H  H    . GLU A 1 271 ? -29.207 14.239  41.816 1   51.399  ? 260 GLU A H    1 
ATOM   3868 H  HA   . GLU A 1 271 ? -28.871 12.532  39.639 1   55.418  ? 260 GLU A HA   1 
ATOM   3869 H  HB2  . GLU A 1 271 ? -27.298 14.835  40.293 1   65.176  ? 260 GLU A HB2  1 
ATOM   3870 H  HB3  . GLU A 1 271 ? -27.078 13.963  38.989 1   65.035  ? 260 GLU A HB3  1 
ATOM   3871 H  HG2  . GLU A 1 271 ? -29.091 14.662  38.086 1   73.905  ? 260 GLU A HG2  1 
ATOM   3872 H  HG3  . GLU A 1 271 ? -29.51  15.366  39.438 1   73.797  ? 260 GLU A HG3  1 
ATOM   3873 N  N    . LEU A 1 272 ? -27.109 12.286  42.229 1   48.967  ? 261 LEU A N    1 
ATOM   3874 C  CA   . LEU A 1 272 ? -25.982 11.676  42.921 1   43.54   ? 261 LEU A CA   1 
ATOM   3875 C  C    . LEU A 1 272 ? -26.398 11.393  44.357 1   43.919  ? 261 LEU A C    1 
ATOM   3876 O  O    . LEU A 1 272 ? -27.104 12.198  44.958 1   47.482  ? 261 LEU A O    1 
ATOM   3877 C  CB   . LEU A 1 272 ? -24.761 12.586  42.887 1   50.174  ? 261 LEU A CB   1 
ATOM   3878 C  CG   . LEU A 1 272 ? -23.525 12.125  43.674 1   47.448  ? 261 LEU A CG   1 
ATOM   3879 C  CD1  . LEU A 1 272 ? -22.886 10.864  43.089 1   52.056  ? 261 LEU A CD1  1 
ATOM   3880 C  CD2  . LEU A 1 272 ? -22.487 13.225  43.715 1   43.761  ? 261 LEU A CD2  1 
ATOM   3881 H  H    . LEU A 1 272 ? -27.761 12.678  42.735 1   47.89   ? 261 LEU A H    1 
ATOM   3882 H  HA   . LEU A 1 272 ? -25.765 10.82   42.472 1   45.688  ? 261 LEU A HA   1 
ATOM   3883 H  HB2  . LEU A 1 272 ? -24.498 12.708  41.946 1   47.956  ? 261 LEU A HB2  1 
ATOM   3884 H  HB3  . LEU A 1 272 ? -25.03  13.47   43.228 1   47.953  ? 261 LEU A HB3  1 
ATOM   3885 H  HG   . LEU A 1 272 ? -23.802 11.929  44.606 1   48.007  ? 261 LEU A HG   1 
ATOM   3886 H  HD11 . LEU A 1 272 ? -23.53  10.137  43.103 1   50.658  ? 261 LEU A HD11 1 
ATOM   3887 H  HD12 . LEU A 1 272 ? -22.109 10.618  43.62  1   50.658  ? 261 LEU A HD12 1 
ATOM   3888 H  HD13 . LEU A 1 272 ? -22.61  11.034  42.173 1   50.658  ? 261 LEU A HD13 1 
ATOM   3889 H  HD21 . LEU A 1 272 ? -22.861 14.01   44.151 1   44.823  ? 261 LEU A HD21 1 
ATOM   3890 H  HD22 . LEU A 1 272 ? -22.221 13.455  42.809 1   44.823  ? 261 LEU A HD22 1 
ATOM   3891 H  HD23 . LEU A 1 272 ? -21.709 12.92   44.213 1   44.823  ? 261 LEU A HD23 1 
ATOM   3892 N  N    . ILE A 1 273 ? -26.051 10.183  44.817 1   38.418  ? 262 ILE A N    1 
ATOM   3893 C  CA   . ILE A 1 273 ? -26.202 9.816   46.208 1   41.051  ? 262 ILE A CA   1 
ATOM   3894 C  C    . ILE A 1 273 ? -24.807 9.674   46.821 1   42.401  ? 262 ILE A C    1 
ATOM   3895 O  O    . ILE A 1 273 ? -23.948 9.038   46.209 1   37.509  ? 262 ILE A O    1 
ATOM   3896 C  CB   . ILE A 1 273 ? -26.984 8.519   46.31  1   39.722  ? 262 ILE A CB   1 
ATOM   3897 C  CG1  . ILE A 1 273 ? -28.367 8.718   45.687 1   44.774  ? 262 ILE A CG1  1 
ATOM   3898 C  CG2  . ILE A 1 273 ? -27.081 8.067   47.782 1   33.589  ? 262 ILE A CG2  1 
ATOM   3899 C  CD1  . ILE A 1 273 ? -29.177 7.451   45.612 1   46.568  ? 262 ILE A CD1  1 
ATOM   3900 H  H    . ILE A 1 273 ? -25.709 9.565   44.238 1   40.331  ? 262 ILE A H    1 
ATOM   3901 H  HA   . ILE A 1 273 ? -26.692 10.519  46.674 1   40.528  ? 262 ILE A HA   1 
ATOM   3902 H  HB   . ILE A 1 273 ? -26.511 7.831   45.802 1   39.628  ? 262 ILE A HB   1 
ATOM   3903 H  HG12 . ILE A 1 273 ? -28.86  9.378   46.216 1   43.966  ? 262 ILE A HG12 1 
ATOM   3904 H  HG13 . ILE A 1 273 ? -28.26  9.076   44.782 1   43.939  ? 262 ILE A HG13 1 
ATOM   3905 H  HG21 . ILE A 1 273 ? -27.627 7.266   47.844 1   35.4    ? 262 ILE A HG21 1 
ATOM   3906 H  HG22 . ILE A 1 273 ? -27.486 8.773   48.314 1   35.309  ? 262 ILE A HG22 1 
ATOM   3907 H  HG23 . ILE A 1 273 ? -26.193 7.875   48.126 1   35.336  ? 262 ILE A HG23 1 
ATOM   3908 H  HD11 . ILE A 1 273 ? -28.632 6.736   45.234 1   45.989  ? 262 ILE A HD11 1 
ATOM   3909 H  HD12 . ILE A 1 273 ? -29.958 7.597   45.044 1   45.988  ? 262 ILE A HD12 1 
ATOM   3910 H  HD13 . ILE A 1 273 ? -29.472 7.195   46.506 1   45.866  ? 262 ILE A HD13 1 
ATOM   3911 N  N    . ILE A 1 274 ? -24.636 10.318  47.984 1   37.456  ? 263 ILE A N    1 
ATOM   3912 C  CA   . ILE A 1 274 ? -23.423 10.298  48.776 1   35.689  ? 263 ILE A CA   1 
ATOM   3913 C  C    . ILE A 1 274 ? -23.781 9.722   50.119 1   37.531  ? 263 ILE A C    1 
ATOM   3914 O  O    . ILE A 1 274 ? -24.731 10.182  50.753 1   34.175  ? 263 ILE A O    1 
ATOM   3915 C  CB   . ILE A 1 274 ? -22.834 11.694  48.928 1   35.003  ? 263 ILE A CB   1 
ATOM   3916 C  CG1  . ILE A 1 274 ? -22.477 12.218  47.612 1   36.402  ? 263 ILE A CG1  1 
ATOM   3917 C  CG2  . ILE A 1 274 ? -21.61  11.679  49.857 1   40.363  ? 263 ILE A CG2  1 
ATOM   3918 C  CD1  . ILE A 1 274 ? -22.091 13.665  47.615 1   32.817  ? 263 ILE A CD1  1 
ATOM   3919 H  H    . ILE A 1 274 ? -25.338 10.809  48.303 1   38.189  ? 263 ILE A H    1 
ATOM   3920 H  HA   . ILE A 1 274 ? -22.769 9.726   48.34  1   36.256  ? 263 ILE A HA   1 
ATOM   3921 H  HB   . ILE A 1 274 ? -23.515 12.276  49.318 1   36.313  ? 263 ILE A HB   1 
ATOM   3922 H  HG12 . ILE A 1 274 ? -21.73  11.694  47.258 1   35.226  ? 263 ILE A HG12 1 
ATOM   3923 H  HG13 . ILE A 1 274 ? -23.238 12.101  47.007 1   35.261  ? 263 ILE A HG13 1 
ATOM   3924 H  HG21 . ILE A 1 274 ? -21.251 12.578  49.94  1   38.648  ? 263 ILE A HG21 1 
ATOM   3925 H  HG22 . ILE A 1 274 ? -20.928 11.093  49.488 1   38.702  ? 263 ILE A HG22 1 
ATOM   3926 H  HG23 . ILE A 1 274 ? -21.87  11.357  50.736 1   38.712  ? 263 ILE A HG23 1 
ATOM   3927 H  HD11 . ILE A 1 274 ? -22.713 14.17   48.172 1   33.886  ? 263 ILE A HD11 1 
ATOM   3928 H  HD12 . ILE A 1 274 ? -22.12  14.009  46.702 1   33.87   ? 263 ILE A HD12 1 
ATOM   3929 H  HD13 . ILE A 1 274 ? -21.186 13.765  47.968 1   33.915  ? 263 ILE A HD13 1 
ATOM   3930 N  N    . ILE A 1 275 ? -23.058 8.672   50.501 1   34.071  ? 264 ILE A N    1 
ATOM   3931 C  CA   . ILE A 1 275 ? -23.209 8.141   51.838 1   32.418  ? 264 ILE A CA   1 
ATOM   3932 C  C    . ILE A 1 275 ? -22.102 8.716   52.711 1   31.197  ? 264 ILE A C    1 
ATOM   3933 O  O    . ILE A 1 275 ? -20.91  8.56    52.373 1   36.364  ? 264 ILE A O    1 
ATOM   3934 C  CB   . ILE A 1 275 ? -23.145 6.601   51.876 1   33.037  ? 264 ILE A CB   1 
ATOM   3935 C  CG1  . ILE A 1 275 ? -23.995 5.971   50.802 1   41.464  ? 264 ILE A CG1  1 
ATOM   3936 C  CG2  . ILE A 1 275 ? -23.485 6.113   53.294 1   33.584  ? 264 ILE A CG2  1 
ATOM   3937 C  CD1  . ILE A 1 275 ? -25.406 6.493   50.81  1   40.602  ? 264 ILE A CD1  1 
ATOM   3938 H  H    . ILE A 1 275 ? -22.466 8.279   49.926 1   34.501  ? 264 ILE A H    1 
ATOM   3939 H  HA   . ILE A 1 275 ? -24.07  8.423   52.193 1   32.756  ? 264 ILE A HA   1 
ATOM   3940 H  HB   . ILE A 1 275 ? -22.219 6.346   51.695 1   34.482  ? 264 ILE A HB   1 
ATOM   3941 H  HG12 . ILE A 1 275 ? -23.592 6.15    49.928 1   39.129  ? 264 ILE A HG12 1 
ATOM   3942 H  HG13 . ILE A 1 275 ? -24.012 5.001   50.935 1   39.119  ? 264 ILE A HG13 1 
ATOM   3943 H  HG21 . ILE A 1 275 ? -23.677 5.161   53.273 1   33.462  ? 264 ILE A HG21 1 
ATOM   3944 H  HG22 . ILE A 1 275 ? -24.264 6.59    53.626 1   33.45   ? 264 ILE A HG22 1 
ATOM   3945 H  HG23 . ILE A 1 275 ? -22.731 6.276   53.886 1   33.425  ? 264 ILE A HG23 1 
ATOM   3946 H  HD11 . ILE A 1 275 ? -25.748 6.497   51.723 1   40.789  ? 264 ILE A HD11 1 
ATOM   3947 H  HD12 . ILE A 1 275 ? -25.967 5.915   50.258 1   40.801  ? 264 ILE A HD12 1 
ATOM   3948 H  HD13 . ILE A 1 275 ? -25.43  7.4     50.451 1   40.737  ? 264 ILE A HD13 1 
ATOM   3949 N  N    . ALA A 1 276 ? -22.493 9.318   53.843 1   35.475  ? 265 ALA A N    1 
ATOM   3950 C  CA   . ALA A 1 276 ? -21.558 9.546   54.943 1   35.099  ? 265 ALA A CA   1 
ATOM   3951 C  C    . ALA A 1 276 ? -21.5   8.243   55.737 1   30.824  ? 265 ALA A C    1 
ATOM   3952 O  O    . ALA A 1 276 ? -22.427 7.914   56.477 1   35.589  ? 265 ALA A O    1 
ATOM   3953 C  CB   . ALA A 1 276 ? -21.954 10.711  55.85  1   32.418  ? 265 ALA A CB   1 
ATOM   3954 H  H    . ALA A 1 276 ? -23.358 9.597   53.934 1   34.293  ? 265 ALA A H    1 
ATOM   3955 H  HA   . ALA A 1 276 ? -20.655 9.724   54.56  1   33.809  ? 265 ALA A HA   1 
ATOM   3956 H  HB1  . ALA A 1 276 ? -21.964 11.536  55.335 1   33.223  ? 265 ALA A HB1  1 
ATOM   3957 H  HB2  . ALA A 1 276 ? -22.836 10.554  56.219 1   33.316  ? 265 ALA A HB2  1 
ATOM   3958 H  HB3  . ALA A 1 276 ? -21.314 10.795  56.575 1   33.255  ? 265 ALA A HB3  1 
ATOM   3959 N  N    . CYS A 1 277 ? -20.448 7.475   55.497 1   30.729  ? 266 CYS A N    1 
ATOM   3960 C  CA   . CYS A 1 277 ? -20.406 6.057   55.873 1   30.448  ? 266 CYS A CA   1 
ATOM   3961 C  C    . CYS A 1 277 ? -19.531 5.908   57.122 1   31.785  ? 266 CYS A C    1 
ATOM   3962 O  O    . CYS A 1 277 ? -18.315 5.741   57.039 1   32.827  ? 266 CYS A O    1 
ATOM   3963 C  CB   . CYS A 1 277 ? -19.805 5.249   54.725 1   28.536  ? 266 CYS A CB   1 
ATOM   3964 S  SG   . CYS A 1 277 ? -19.806 3.453   55.001 1   37.968  ? 266 CYS A SG   1 
ATOM   3965 H  H    . CYS A 1 277 ? -19.717 7.838   55.085 1   30.744  ? 266 CYS A H    1 
ATOM   3966 H  HA   . CYS A 1 277 ? -21.325 5.747   56.076 1   30.433  ? 266 CYS A HA   1 
ATOM   3967 H  HB2  . CYS A 1 277 ? -20.313 5.436   53.904 1   30.597  ? 266 CYS A HB2  1 
ATOM   3968 H  HB3  . CYS A 1 277 ? -18.878 5.541   54.577 1   30.606  ? 266 CYS A HB3  1 
ATOM   3969 H  HG   . CYS A 1 277 ? -19.284 3.133   53.954 0   37.98   ? 266 CYS A HG   1 
ATOM   3970 N  N    . GLY A 1 278 ? -20.16  5.977   58.285 1   33.386  ? 267 GLY A N    1 
ATOM   3971 C  CA   . GLY A 1 278 ? -19.561 5.523   59.532 1   34.778  ? 267 GLY A CA   1 
ATOM   3972 C  C    . GLY A 1 278 ? -19.923 4.098   59.866 1   33.042  ? 267 GLY A C    1 
ATOM   3973 O  O    . GLY A 1 278 ? -20.95  3.59    59.453 1   33.282  ? 267 GLY A O    1 
ATOM   3974 H  H    . GLY A 1 278 ? -21.004 6.326   58.31  1   33.259  ? 267 GLY A H    1 
ATOM   3975 H  HA2  . GLY A 1 278 ? -18.581 5.605   59.467 1   33.947  ? 267 GLY A HA2  1 
ATOM   3976 H  HA3  . GLY A 1 278 ? -19.862 6.113   60.261 1   34.027  ? 267 GLY A HA3  1 
ATOM   3977 N  N    . TYR A 1 279 ? -19.059 3.465   60.642 1   27.573  ? 268 TYR A N    1 
ATOM   3978 C  CA   . TYR A 1 279 ? -19.286 2.134   61.106 1   28.689  ? 268 TYR A CA   1 
ATOM   3979 C  C    . TYR A 1 279 ? -19.457 2.091   62.616 1   24.851  ? 268 TYR A C    1 
ATOM   3980 O  O    . TYR A 1 279 ? -19.494 1.024   63.229 1   26.105  ? 268 TYR A O    1 
ATOM   3981 C  CB   . TYR A 1 279 ? -18.069 1.322   60.717 1   32.643  ? 268 TYR A CB   1 
ATOM   3982 C  CG   . TYR A 1 279 ? -17.819 1.265   59.239 1   32.973  ? 268 TYR A CG   1 
ATOM   3983 C  CD1  . TYR A 1 279 ? -18.46  0.357   58.465 1   36.068  ? 268 TYR A CD1  1 
ATOM   3984 C  CD2  . TYR A 1 279 ? -16.967 2.163   58.634 1   39.384  ? 268 TYR A CD2  1 
ATOM   3985 C  CE1  . TYR A 1 279 ? -18.35  0.383   57.096 1   36.35   ? 268 TYR A CE1  1 
ATOM   3986 C  CE2  . TYR A 1 279 ? -16.768 2.146   57.281 1   37.841  ? 268 TYR A CE2  1 
ATOM   3987 C  CZ   . TYR A 1 279 ? -17.472 1.249   56.512 1   35.15   ? 268 TYR A CZ   1 
ATOM   3988 O  OH   . TYR A 1 279 ? -17.261 1.19    55.184 1   36.987  ? 268 TYR A OH   1 
ATOM   3989 H  H    . TYR A 1 279 ? -18.287 3.888   60.89  1   29.127  ? 268 TYR A H    1 
ATOM   3990 H  HA   . TYR A 1 279 ? -20.091 1.755   60.666 1   28.494  ? 268 TYR A HA   1 
ATOM   3991 H  HB2  . TYR A 1 279 ? -17.281 1.711   61.158 1   31.775  ? 268 TYR A HB2  1 
ATOM   3992 H  HB3  . TYR A 1 279 ? -18.182 0.406   61.055 1   31.695  ? 268 TYR A HB3  1 
ATOM   3993 H  HD1  . TYR A 1 279 ? -19.093 -0.219  58.862 1   35.4    ? 268 TYR A HD1  1 
ATOM   3994 H  HD2  . TYR A 1 279 ? -16.502 2.791   59.163 1   37.338  ? 268 TYR A HD2  1 
ATOM   3995 H  HE1  . TYR A 1 279 ? -18.783 -0.272  56.575 1   35.98   ? 268 TYR A HE1  1 
ATOM   3996 H  HE2  . TYR A 1 279 ? -16.179 2.755   56.878 1   37.509  ? 268 TYR A HE2  1 
ATOM   3997 H  HH   . TYR A 1 279 ? -17.823 1.706   54.783 0   37.07   ? 268 TYR A HH   1 
ATOM   3998 N  N    . ASP A 1 280 ? -19.619 3.233   63.228 1   26.906  ? 269 ASP A N    1 
ATOM   3999 C  CA   . ASP A 1 280 ? -19.749 3.222   64.677 1   28.239  ? 269 ASP A CA   1 
ATOM   4000 C  C    . ASP A 1 280 ? -21.12  2.802   65.221 1   26.966  ? 269 ASP A C    1 
ATOM   4001 O  O    . ASP A 1 280 ? -21.287 2.721   66.438 1   30.049  ? 269 ASP A O    1 
ATOM   4002 C  CB   . ASP A 1 280 ? -19.271 4.529   65.222 1   29.603  ? 269 ASP A CB   1 
ATOM   4003 C  CG   . ASP A 1 280 ? -19.714 5.785   64.471 1   34.719  ? 269 ASP A CG   1 
ATOM   4004 O  OD1  . ASP A 1 280 ? -20.589 5.728   63.621 1   30.762  ? 269 ASP A OD1  1 
ATOM   4005 O  OD2  . ASP A 1 280 ? -19.224 6.845   64.804 1   29.508  ? 269 ASP A OD2  1 
ATOM   4006 H  H    . ASP A 1 280 ? -19.665 4.02    62.768 1   26.82   ? 269 ASP A H    1 
ATOM   4007 H  HA   . ASP A 1 280 ? -19.097 2.573   65.023 1   27.981  ? 269 ASP A HA   1 
ATOM   4008 H  HB2  . ASP A 1 280 ? -19.582 4.616   66.147 1   30.36   ? 269 ASP A HB2  1 
ATOM   4009 H  HB3  . ASP A 1 280 ? -18.293 4.525   65.247 1   30.428  ? 269 ASP A HB3  1 
ATOM   4010 N  N    . ALA A 1 281 ? -22.06  2.397   64.382 1   26.711  ? 270 ALA A N    1 
ATOM   4011 C  CA   . ALA A 1 281 ? -23.222 1.629   64.863 1   33.485  ? 270 ALA A CA   1 
ATOM   4012 C  C    . ALA A 1 281 ? -22.966 0.128   65.028 1   31.608  ? 270 ALA A C    1 
ATOM   4013 O  O    . ALA A 1 281 ? -23.901 -0.644  65.314 1   24.09   ? 270 ALA A O    1 
ATOM   4014 C  CB   . ALA A 1 281 ? -24.37  1.851   63.893 1   35.532  ? 270 ALA A CB   1 
ATOM   4015 H  H    . ALA A 1 281 ? -22.002 2.605   63.494 1   28.17   ? 270 ALA A H    1 
ATOM   4016 H  HA   . ALA A 1 281 ? -23.485 1.993   65.753 1   31.982  ? 270 ALA A HA   1 
ATOM   4017 H  HB1  . ALA A 1 281 ? -24.569 2.8     63.834 1   34.866  ? 270 ALA A HB1  1 
ATOM   4018 H  HB2  . ALA A 1 281 ? -24.122 1.52    63.013 1   34.843  ? 270 ALA A HB2  1 
ATOM   4019 H  HB3  . ALA A 1 281 ? -25.159 1.376   64.204 1   34.822  ? 270 ALA A HB3  1 
ATOM   4020 N  N    . ASN A 1 282 ? -21.716 -0.328  64.81  1   27.536  ? 271 ASN A N    1 
ATOM   4021 C  CA   . ASN A 1 282 ? -21.39  -1.75   64.957 1   24.165  ? 271 ASN A CA   1 
ATOM   4022 C  C    . ASN A 1 282 ? -21.442 -2.127  66.434 1   27.005  ? 271 ASN A C    1 
ATOM   4023 O  O    . ASN A 1 282 ? -21.328 -1.277  67.313 1   26.905  ? 271 ASN A O    1 
ATOM   4024 C  CB   . ASN A 1 282 ? -20.031 -2.123  64.369 1   30.391  ? 271 ASN A CB   1 
ATOM   4025 C  CG   . ASN A 1 282 ? -18.911 -1.769  65.332 1   32.811  ? 271 ASN A CG   1 
ATOM   4026 O  OD1  . ASN A 1 282 ? -18.681 -2.482  66.311 1   30.497  ? 271 ASN A OD1  1 
ATOM   4027 N  ND2  . ASN A 1 282 ? -18.402 -0.562  65.218 1   28.811  ? 271 ASN A ND2  1 
ATOM   4028 H  H    . ASN A 1 282 ? -21.056 0.25    64.556 1   27.695  ? 271 ASN A H    1 
ATOM   4029 H  HA   . ASN A 1 282 ? -22.071 -2.27   64.477 1   26.448  ? 271 ASN A HA   1 
ATOM   4030 H  HB2  . ASN A 1 282 ? -20.01  -3.083  64.184 1   29.379  ? 271 ASN A HB2  1 
ATOM   4031 H  HB3  . ASN A 1 282 ? -19.899 -1.645  63.526 1   29.348  ? 271 ASN A HB3  1 
ATOM   4032 H  HD21 . ASN A 1 282 ? -17.75  -0.306  65.763 1   29.987  ? 271 ASN A HD21 1 
ATOM   4033 H  HD22 . ASN A 1 282 ? -18.707 -0.003  64.601 1   29.967  ? 271 ASN A HD22 1 
ATOM   4034 N  N    . ALA A 1 283 ? -21.753 -3.41   66.675 1   25.717  ? 272 ALA A N    1 
ATOM   4035 C  CA   . ALA A 1 283 ? -22.189 -3.903  67.95  1   29.433  ? 272 ALA A CA   1 
ATOM   4036 C  C    . ALA A 1 283 ? -21.087 -3.839  68.996 1   31.627  ? 272 ALA A C    1 
ATOM   4037 O  O    . ALA A 1 283 ? -21.376 -4.121  70.157 1   26.205  ? 272 ALA A O    1 
ATOM   4038 C  CB   . ALA A 1 283 ? -22.661 -5.361  67.774 1   30.54   ? 272 ALA A CB   1 
ATOM   4039 H  H    . ALA A 1 283 ? -21.68  -4.007  65.987 1   26.863  ? 272 ALA A H    1 
ATOM   4040 H  HA   . ALA A 1 283 ? -22.949 -3.344  68.261 1   29.247  ? 272 ALA A HA   1 
ATOM   4041 H  HB1  . ALA A 1 283 ? -23.431 -5.387  67.181 1   30.207  ? 272 ALA A HB1  1 
ATOM   4042 H  HB2  . ALA A 1 283 ? -21.944 -5.893  67.391 1   30.191  ? 272 ALA A HB2  1 
ATOM   4043 H  HB3  . ALA A 1 283 ? -22.908 -5.731  68.637 1   30.2    ? 272 ALA A HB3  1 
ATOM   4044 N  N    . MET A 1 284 ? -19.822 -3.601  68.594 1   30.538  ? 273 MET A N    1 
ATOM   4045 C  CA   . MET A 1 284 ? -18.707 -3.581  69.514 1   31.525  ? 273 MET A CA   1 
ATOM   4046 C  C    . MET A 1 284 ? -18.142 -2.166  69.69  1   32.113  ? 273 MET A C    1 
ATOM   4047 O  O    . MET A 1 284 ? -17.085 -2.013  70.272 1   32.805  ? 273 MET A O    1 
ATOM   4048 C  CB   . MET A 1 284 ? -17.526 -4.418  68.985 1   39.383  ? 273 MET A CB   1 
ATOM   4049 C  CG   . MET A 1 284 ? -17.82  -5.9    68.751 1   40.609  ? 273 MET A CG   1 
ATOM   4050 S  SD   . MET A 1 284 ? -18.26  -6.894  70.212 1   50.161  ? 273 MET A SD   1 
ATOM   4051 C  CE   . MET A 1 284 ? -19.993 -7.311  69.963 1   62.437  ? 273 MET A CE   1 
ATOM   4052 H  H    . MET A 1 284 ? -19.653 -3.463  67.707 1   30.933  ? 273 MET A H    1 
ATOM   4053 H  HA   . MET A 1 284 ? -19.002 -3.929  70.393 1   32.722  ? 273 MET A HA   1 
ATOM   4054 H  HB2  . MET A 1 284 ? -17.223 -4.023  68.139 1   37.659  ? 273 MET A HB2  1 
ATOM   4055 H  HB3  . MET A 1 284 ? -16.786 -4.347  69.624 1   37.635  ? 273 MET A HB3  1 
ATOM   4056 H  HG2  . MET A 1 284 ? -18.554 -5.971  68.109 1   41.894  ? 273 MET A HG2  1 
ATOM   4057 H  HG3  . MET A 1 284 ? -17.034 -6.308  68.337 1   41.949  ? 273 MET A HG3  1 
ATOM   4058 H  HE1  . MET A 1 284 ? -20.25  -8.015  70.587 1   59.019  ? 273 MET A HE1  1 
ATOM   4059 H  HE2  . MET A 1 284 ? -20.543 -6.522  70.118 1   58.753  ? 273 MET A HE2  1 
ATOM   4060 H  HE3  . MET A 1 284 ? -20.124 -7.625  69.049 1   59.023  ? 273 MET A HE3  1 
ATOM   4061 N  N    . ASP A 1 285 ? -18.857 -1.14   69.255 1   30.988  ? 274 ASP A N    1 
ATOM   4062 C  CA   . ASP A 1 285 ? -18.31  0.185   69.335 1   34.428  ? 274 ASP A CA   1 
ATOM   4063 C  C    . ASP A 1 285 ? -18.461 0.783   70.716 1   31.492  ? 274 ASP A C    1 
ATOM   4064 O  O    . ASP A 1 285 ? -19.525 0.738   71.297 1   34.966  ? 274 ASP A O    1 
ATOM   4065 C  CB   . ASP A 1 285 ? -18.857 1.082   68.277 1   29.923  ? 274 ASP A CB   1 
ATOM   4066 C  CG   . ASP A 1 285 ? -17.803 2.069   67.798 1   34.922  ? 274 ASP A CG   1 
ATOM   4067 O  OD1  . ASP A 1 285 ? -17.701 3.125   68.46  1   35.801  ? 274 ASP A OD1  1 
ATOM   4068 O  OD2  . ASP A 1 285 ? -17.224 1.841   66.678 1   31.579  ? 274 ASP A OD2  1 
ATOM   4069 H  H    . ASP A 1 285 ? -19.696 -1.263  68.914 1   31.978  ? 274 ASP A H    1 
ATOM   4070 H  HA   . ASP A 1 285 ? -17.35  0.115   69.138 1   32.404  ? 274 ASP A HA   1 
ATOM   4071 H  HB2  . ASP A 1 285 ? -19.159 0.548   67.514 1   31.989  ? 274 ASP A HB2  1 
ATOM   4072 H  HB3  . ASP A 1 285 ? -19.624 1.582   68.628 1   32.005  ? 274 ASP A HB3  1 
ATOM   4073 N  N    . PRO A 1 286 ? -17.393 1.373   71.28  1   31.492  ? 275 PRO A N    1 
ATOM   4074 C  CA   . PRO A 1 286 ? -17.482 2.067   72.56  1   31.922  ? 275 PRO A CA   1 
ATOM   4075 C  C    . PRO A 1 286 ? -18.136 3.454   72.45  1   32.008  ? 275 PRO A C    1 
ATOM   4076 O  O    . PRO A 1 286 ? -18.535 3.953   73.488 1   30.603  ? 275 PRO A O    1 
ATOM   4077 C  CB   . PRO A 1 286 ? -15.997 2.18    72.997 1   38.136  ? 275 PRO A CB   1 
ATOM   4078 C  CG   . PRO A 1 286 ? -15.224 2.178   71.696 1   36.825  ? 275 PRO A CG   1 
ATOM   4079 C  CD   . PRO A 1 286 ? -16.006 1.338   70.745 1   38.579  ? 275 PRO A CD   1 
ATOM   4080 H  HA   . PRO A 1 286 ? -17.977 1.507   73.209 1   32.892  ? 275 PRO A HA   1 
ATOM   4081 H  HB2  . PRO A 1 286 ? -15.839 3.014   73.499 1   36.355  ? 275 PRO A HB2  1 
ATOM   4082 H  HB3  . PRO A 1 286 ? -15.737 1.414   73.562 1   36.376  ? 275 PRO A HB3  1 
ATOM   4083 H  HG2  . PRO A 1 286 ? -15.131 3.091   71.35  1   37.516  ? 275 PRO A HG2  1 
ATOM   4084 H  HG3  . PRO A 1 286 ? -14.328 1.803   71.828 1   37.516  ? 275 PRO A HG3  1 
ATOM   4085 H  HD2  . PRO A 1 286 ? -15.966 1.713   69.839 1   36.381  ? 275 PRO A HD2  1 
ATOM   4086 H  HD3  . PRO A 1 286 ? -15.66  0.419   70.726 1   36.398  ? 275 PRO A HD3  1 
ATOM   4087 N  N    . LEU A 1 287 ? -18.325 4.042   71.248 1   26.768  ? 276 LEU A N    1 
ATOM   4088 C  CA   . LEU A 1 287 ? -18.85  5.433   71.093 1   28.512  ? 276 LEU A CA   1 
ATOM   4089 C  C    . LEU A 1 287 ? -20.349 5.538   70.768 1   27.494  ? 276 LEU A C    1 
ATOM   4090 O  O    . LEU A 1 287 ? -20.902 6.668   70.668 1   29.485  ? 276 LEU A O    1 
ATOM   4091 C  CB   . LEU A 1 287 ? -18.032 6.228   70.077 1   31.822  ? 276 LEU A CB   1 
ATOM   4092 C  CG   . LEU A 1 287 ? -16.512 6.203   70.36  1   34.78   ? 276 LEU A CG   1 
ATOM   4093 C  CD1  . LEU A 1 287 ? -15.748 7.197   69.548 1   43.404  ? 276 LEU A CD1  1 
ATOM   4094 C  CD2  . LEU A 1 287 ? -16.164 6.566   71.776 1   36.502  ? 276 LEU A CD2  1 
ATOM   4095 H  H    . LEU A 1 287 ? -18.119 3.573   70.492 1   28.372  ? 276 LEU A H    1 
ATOM   4096 H  HA   . LEU A 1 287 ? -18.737 5.875   71.972 1   28.658  ? 276 LEU A HA   1 
ATOM   4097 H  HB2  . LEU A 1 287 ? -18.193 5.851   69.182 1   31.655  ? 276 LEU A HB2  1 
ATOM   4098 H  HB3  . LEU A 1 287 ? -18.34  7.163   70.09  1   31.646  ? 276 LEU A HB3  1 
ATOM   4099 H  HG   . LEU A 1 287 ? -16.165 5.294   70.165 1   35.966  ? 276 LEU A HG   1 
ATOM   4100 H  HD11 . LEU A 1 287 ? -16.004 7.114   68.614 1   41.072  ? 276 LEU A HD11 1 
ATOM   4101 H  HD12 . LEU A 1 287 ? -14.795 7.028   69.639 1   40.813  ? 276 LEU A HD12 1 
ATOM   4102 H  HD13 . LEU A 1 287 ? -15.948 8.096   69.859 1   40.681  ? 276 LEU A HD13 1 
ATOM   4103 H  HD21 . LEU A 1 287 ? -16.444 5.853   72.374 1   35.915  ? 276 LEU A HD21 1 
ATOM   4104 H  HD22 . LEU A 1 287 ? -16.617 7.389   72.02  1   36.124  ? 276 LEU A HD22 1 
ATOM   4105 H  HD23 . LEU A 1 287 ? -15.203 6.692   71.855 1   36.066  ? 276 LEU A HD23 1 
ATOM   4106 N  N    . ALA A 1 288 ? -21.027 4.388   70.819 1   26.67   ? 277 ALA A N    1 
ATOM   4107 C  CA   . ALA A 1 288 ? -22.486 4.302   70.705 1   31.829  ? 277 ALA A CA   1 
ATOM   4108 C  C    . ALA A 1 288 ? -22.976 2.922   71.128 1   33.677  ? 277 ALA A C    1 
ATOM   4109 O  O    . ALA A 1 288 ? -22.182 2.062   71.535 1   29.272  ? 277 ALA A O    1 
ATOM   4110 C  CB   . ALA A 1 288 ? -22.897 4.587   69.287 1   32.771  ? 277 ALA A CB   1 
ATOM   4111 H  H    . ALA A 1 288 ? -20.56  3.61    70.924 1   28.006  ? 277 ALA A H    1 
ATOM   4112 H  HA   . ALA A 1 288 ? -22.892 4.981   71.312 1   31.264  ? 277 ALA A HA   1 
ATOM   4113 H  HB1  . ALA A 1 288 ? -22.497 5.421   68.991 1   32.447  ? 277 ALA A HB1  1 
ATOM   4114 H  HB2  . ALA A 1 288 ? -22.597 3.865   68.709 1   32.475  ? 277 ALA A HB2  1 
ATOM   4115 H  HB3  . ALA A 1 288 ? -23.864 4.661   69.233 1   32.431  ? 277 ALA A HB3  1 
ATOM   4116 N  N    . ARG A 1 289 ? -24.305 2.739   71.099 1   25.586  ? 278 ARG A N    1 
ATOM   4117 C  CA   . ARG A 1 289 ? -24.926 1.562   71.667 1   29.574  ? 278 ARG A CA   1 
ATOM   4118 C  C    . ARG A 1 289 ? -25.762 0.787   70.657 1   30.51   ? 278 ARG A C    1 
ATOM   4119 O  O    . ARG A 1 289 ? -26.724 0.14    71.067 1   31.917  ? 278 ARG A O    1 
ATOM   4120 C  CB   . ARG A 1 289 ? -25.844 2.097   72.766 1   35.065  ? 278 ARG A CB   1 
ATOM   4121 C  CG   . ARG A 1 289 ? -25.255 3.108   73.734 1   30.725  ? 278 ARG A CG   1 
ATOM   4122 C  CD   . ARG A 1 289 ? -24.364 2.497   74.807 1   31.697  ? 278 ARG A CD   1 
ATOM   4123 N  NE   . ARG A 1 289 ? -22.994 2.34    74.31  1   38.193  ? 278 ARG A NE   1 
ATOM   4124 C  CZ   . ARG A 1 289 ? -22.175 1.433   74.77  1   30.351  ? 278 ARG A CZ   1 
ATOM   4125 N  NH1  . ARG A 1 289 ? -22.372 0.883   75.948 1   33.542  ? 278 ARG A NH1  1 
ATOM   4126 N  NH2  . ARG A 1 289 ? -21.036 1.25    74.17  1   34.597  ? 278 ARG A NH2  1 
ATOM   4127 H  H    . ARG A 1 289 ? -24.839 3.376   70.72  1   28.313  ? 278 ARG A H    1 
ATOM   4128 H  HA   . ARG A 1 289 ? -24.236 0.967   72.054 1   29.837  ? 278 ARG A HA   1 
ATOM   4129 H  HB2  . ARG A 1 289 ? -26.624 2.509   72.336 1   32.712  ? 278 ARG A HB2  1 
ATOM   4130 H  HB3  . ARG A 1 289 ? -26.172 1.333   73.287 1   32.715  ? 278 ARG A HB3  1 
ATOM   4131 H  HG2  . ARG A 1 289 ? -24.737 3.772   73.232 1   31.897  ? 278 ARG A HG2  1 
ATOM   4132 H  HG3  . ARG A 1 289 ? -25.99  3.588   74.174 1   31.894  ? 278 ARG A HG3  1 
ATOM   4133 H  HD2  . ARG A 1 289 ? -24.354 3.073   75.596 1   32.9    ? 278 ARG A HD2  1 
ATOM   4134 H  HD3  . ARG A 1 289 ? -24.717 1.626   75.07  1   32.881  ? 278 ARG A HD3  1 
ATOM   4135 H  HE   . ARG A 1 289 ? -22.711 2.891   73.7   1   34.58   ? 278 ARG A HE   1 
ATOM   4136 H  HH11 . ARG A 1 289 ? -22.448 1.394   76.665 1   32.521  ? 278 ARG A HH11 1 
ATOM   4137 H  HH12 . ARG A 1 289 ? -22.429 0.003   76.018 1   32.524  ? 278 ARG A HH12 1 
ATOM   4138 H  HH21 . ARG A 1 289 ? -20.728 1.847   73.594 1   33.276  ? 278 ARG A HH21 1 
ATOM   4139 H  HH22 . ARG A 1 289 ? -20.564 0.525   74.346 1   33.238  ? 278 ARG A HH22 1 
ATOM   4140 N  N    . MET A 1 290 ? -25.436 0.836   69.349 1   29.658  ? 279 MET A N    1 
ATOM   4141 C  CA   . MET A 1 290 ? -26.207 0.088   68.37  1   27.03   ? 279 MET A CA   1 
ATOM   4142 C  C    . MET A 1 290 ? -25.634 -1.302  68.216 1   32.001  ? 279 MET A C    1 
ATOM   4143 O  O    . MET A 1 290 ? -24.54  -1.518  68.714 1   27.395  ? 279 MET A O    1 
ATOM   4144 C  CB   . MET A 1 290 ? -26.316 0.817   67.043 1   24.927  ? 279 MET A CB   1 
ATOM   4145 C  CG   . MET A 1 290 ? -26.961 2.18    67.289 1   27.999  ? 279 MET A CG   1 
ATOM   4146 S  SD   . MET A 1 290 ? -28.753 2.006   67.592 1   32.912  ? 279 MET A SD   1 
ATOM   4147 C  CE   . MET A 1 290 ? -29.144 3.746   67.465 1   33.894  ? 279 MET A CE   1 
ATOM   4148 H  H    . MET A 1 290 ? -24.725 1.338   69.069 1   29.216  ? 279 MET A H    1 
ATOM   4149 H  HA   . MET A 1 290 ? -27.121 -0.019  68.735 1   28.042  ? 279 MET A HA   1 
ATOM   4150 H  HB2  . MET A 1 290 ? -25.422 0.935   66.657 1   26.097  ? 279 MET A HB2  1 
ATOM   4151 H  HB3  . MET A 1 290 ? -26.863 0.294   66.42  1   26.115  ? 279 MET A HB3  1 
ATOM   4152 H  HG2  . MET A 1 290 ? -26.545 2.613   68.06  1   28.093  ? 279 MET A HG2  1 
ATOM   4153 H  HG3  . MET A 1 290 ? -26.825 2.751   66.508 1   28.14   ? 279 MET A HG3  1 
ATOM   4154 H  HE1  . MET A 1 290 ? -30.085 3.849   67.228 1   33.637  ? 279 MET A HE1  1 
ATOM   4155 H  HE2  . MET A 1 290 ? -28.981 4.175   68.324 1   33.602  ? 279 MET A HE2  1 
ATOM   4156 H  HE3  . MET A 1 290 ? -28.588 4.158   66.777 1   33.604  ? 279 MET A HE3  1 
ATOM   4157 N  N    . GLN A 1 291 ? -26.363 -2.186  67.5   1   35.59   ? 280 GLN A N    1 
ATOM   4158 C  CA   . GLN A 1 291 ? -25.977 -3.587  67.395 1   31.288  ? 280 GLN A CA   1 
ATOM   4159 C  C    . GLN A 1 291 ? -25.856 -4.066  65.954 1   32.166  ? 280 GLN A C    1 
ATOM   4160 O  O    . GLN A 1 291 ? -26.159 -5.204  65.689 1   31.195  ? 280 GLN A O    1 
ATOM   4161 C  CB   . GLN A 1 291 ? -26.921 -4.491  68.168 1   31.012  ? 280 GLN A CB   1 
ATOM   4162 C  CG   . GLN A 1 291 ? -26.956 -4.169  69.669 1   32.997  ? 280 GLN A CG   1 
ATOM   4163 C  CD   . GLN A 1 291 ? -27.735 -5.187  70.477 1   40.728  ? 280 GLN A CD   1 
ATOM   4164 O  OE1  . GLN A 1 291 ? -27.226 -6.264  70.799 1   36.976  ? 280 GLN A OE1  1 
ATOM   4165 N  NE2  . GLN A 1 291 ? -28.995 -4.864  70.792 1   36.051  ? 280 GLN A NE2  1 
ATOM   4166 H  H    . GLN A 1 291 ? -27.12  -1.905  67.072 1   33.534  ? 280 GLN A H    1 
ATOM   4167 H  HA   . GLN A 1 291 ? -25.087 -3.687  67.813 1   32.135  ? 280 GLN A HA   1 
ATOM   4168 H  HB2  . GLN A 1 291 ? -27.824 -4.398  67.799 1   31.513  ? 280 GLN A HB2  1 
ATOM   4169 H  HB3  . GLN A 1 291 ? -26.642 -5.422  68.05  1   31.515  ? 280 GLN A HB3  1 
ATOM   4170 H  HG2  . GLN A 1 291 ? -26.04  -4.137  70.011 1   34.17   ? 280 GLN A HG2  1 
ATOM   4171 H  HG3  . GLN A 1 291 ? -27.356 -3.283  69.802 1   34.198  ? 280 GLN A HG3  1 
ATOM   4172 H  HE21 . GLN A 1 291 ? -29.411 -5.297  71.445 1   37.416  ? 280 GLN A HE21 1 
ATOM   4173 H  HE22 . GLN A 1 291 ? -29.415 -4.22   70.348 1   37.369  ? 280 GLN A HE22 1 
ATOM   4174 N  N    . LEU A 1 292 ? -25.329 -3.25   65.035 1   30.554  ? 281 LEU A N    1 
ATOM   4175 C  CA   . LEU A 1 292 ? -25.084 -3.724  63.664 1   28.744  ? 281 LEU A CA   1 
ATOM   4176 C  C    . LEU A 1 292 ? -23.859 -4.63   63.545 1   30.769  ? 281 LEU A C    1 
ATOM   4177 O  O    . LEU A 1 292 ? -22.945 -4.604  64.364 1   35.403  ? 281 LEU A O    1 
ATOM   4178 C  CB   . LEU A 1 292 ? -24.963 -2.562  62.682 1   27.769  ? 281 LEU A CB   1 
ATOM   4179 C  CG   . LEU A 1 292 ? -26.079 -1.522  62.724 1   29.75   ? 281 LEU A CG   1 
ATOM   4180 C  CD1  . LEU A 1 292 ? -25.937 -0.593  61.587 1   27.855  ? 281 LEU A CD1  1 
ATOM   4181 C  CD2  . LEU A 1 292 ? -27.408 -2.264  62.668 1   34.067  ? 281 LEU A CD2  1 
ATOM   4182 H  H    . LEU A 1 292 ? -25.11  -2.391  65.257 1   30.522  ? 281 LEU A H    1 
ATOM   4183 H  HA   . LEU A 1 292 ? -25.87  -4.266  63.401 1   29.362  ? 281 LEU A HA   1 
ATOM   4184 H  HB2  . LEU A 1 292 ? -24.108 -2.104  62.854 1   28.444  ? 281 LEU A HB2  1 
ATOM   4185 H  HB3  . LEU A 1 292 ? -24.919 -2.933  61.772 1   28.438  ? 281 LEU A HB3  1 
ATOM   4186 H  HG   . LEU A 1 292 ? -26.019 -1.015  63.575 1   29.744  ? 281 LEU A HG   1 
ATOM   4187 H  HD11 . LEU A 1 292 ? -25.068 -0.159  61.63  1   28.463  ? 281 LEU A HD11 1 
ATOM   4188 H  HD12 . LEU A 1 292 ? -26.637 0.079   61.627 1   28.453  ? 281 LEU A HD12 1 
ATOM   4189 H  HD13 . LEU A 1 292 ? -26.01  -1.087  60.753 1   28.433  ? 281 LEU A HD13 1 
ATOM   4190 H  HD21 . LEU A 1 292 ? -27.633 -2.596  63.554 1   32.696  ? 281 LEU A HD21 1 
ATOM   4191 H  HD22 . LEU A 1 292 ? -27.339 -3.012  62.051 1   32.638  ? 281 LEU A HD22 1 
ATOM   4192 H  HD23 . LEU A 1 292 ? -28.106 -1.661  62.364 1   32.638  ? 281 LEU A HD23 1 
ATOM   4193 N  N    . HIS A 1 293 ? -23.952 -5.536  62.554 1   31.286  ? 282 HIS A N    1 
ATOM   4194 C  CA   . HIS A 1 293 ? -22.865 -6.41   62.178 1   31.381  ? 282 HIS A CA   1 
ATOM   4195 C  C    . HIS A 1 293 ? -22.569 -6.141  60.704 1   36.031  ? 282 HIS A C    1 
ATOM   4196 O  O    . HIS A 1 293 ? -23.198 -5.275  60.104 1   31.921  ? 282 HIS A O    1 
ATOM   4197 C  CB   . HIS A 1 293 ? -23.203 -7.865  62.465 1   29.891  ? 282 HIS A CB   1 
ATOM   4198 C  CG   . HIS A 1 293 ? -24.5   -8.308  61.933 1   31.86   ? 282 HIS A CG   1 
ATOM   4199 N  ND1  . HIS A 1 293 ? -24.826 -8.279  60.602 1   32.874  ? 282 HIS A ND1  1 
ATOM   4200 C  CD2  . HIS A 1 293 ? -25.613 -8.666  62.576 1   36.897  ? 282 HIS A CD2  1 
ATOM   4201 C  CE1  . HIS A 1 293 ? -26.093 -8.714  60.463 1   37.065  ? 282 HIS A CE1  1 
ATOM   4202 N  NE2  . HIS A 1 293 ? -26.595 -8.918  61.66  1   35.093  ? 282 HIS A NE2  1 
ATOM   4203 H  H    . HIS A 1 293 ? -24.736 -5.596  62.088 1   31.181  ? 282 HIS A H    1 
ATOM   4204 H  HA   . HIS A 1 293 ? -22.066 -6.162  62.702 1   31.918  ? 282 HIS A HA   1 
ATOM   4205 H  HB2  . HIS A 1 293 ? -22.498 -8.434  62.09  1   30.721  ? 282 HIS A HB2  1 
ATOM   4206 H  HB3  . HIS A 1 293 ? -23.197 -8      63.436 1   30.665  ? 282 HIS A HB3  1 
ATOM   4207 H  HD1  . HIS A 1 293 ? -24.434 -8.133  59.888 0   32.64   ? 282 HIS A HD1  1 
ATOM   4208 H  HD2  . HIS A 1 293 ? -25.713 -8.756  63.503 1   35.15   ? 282 HIS A HD2  1 
ATOM   4209 H  HE1  . HIS A 1 293 ? -26.555 -8.803  59.647 1   35.576  ? 282 HIS A HE1  1 
ATOM   4210 H  HE2  . HIS A 1 293 ? -27.531 -9.156  61.827 0   34.84   ? 282 HIS A HE2  1 
ATOM   4211 N  N    . SER A 1 294 ? -21.569 -6.844  60.18  1   32.718  ? 283 SER A N    1 
ATOM   4212 C  CA   . SER A 1 294 ? -21.044 -6.588  58.85  1   34.46   ? 283 SER A CA   1 
ATOM   4213 C  C    . SER A 1 294 ? -22.111 -6.817  57.767 1   35.993  ? 283 SER A C    1 
ATOM   4214 O  O    . SER A 1 294 ? -22.083 -6.128  56.754 1   35.614  ? 283 SER A O    1 
ATOM   4215 C  CB   . SER A 1 294 ? -19.842 -7.488  58.597 1   34.689  ? 283 SER A CB   1 
ATOM   4216 O  OG   . SER A 1 294 ? -20.186 -8.879  58.739 1   31.35   ? 283 SER A OG   1 
ATOM   4217 H  H    . SER A 1 294 ? -21.186 -7.508  60.677 1   33.807  ? 283 SER A H    1 
ATOM   4218 H  HA   . SER A 1 294 ? -20.749 -5.643  58.806 1   34.425  ? 283 SER A HA   1 
ATOM   4219 H  HB2  . SER A 1 294 ? -19.504 -7.328  57.695 1   33.811  ? 283 SER A HB2  1 
ATOM   4220 H  HB3  . SER A 1 294 ? -19.133 -7.264  59.23  1   33.811  ? 283 SER A HB3  1 
ATOM   4221 H  HG   . SER A 1 294 ? -19.74  -9.546  58.535 0   31.09   ? 283 SER A HG   1 
ATOM   4222 N  N    . ASP A 1 295 ? -22.974 -7.826  57.939 1   38.284  ? 284 ASP A N    1 
ATOM   4223 C  CA   . ASP A 1 295 ? -24.115 -8.04   57.038 1   34.476  ? 284 ASP A CA   1 
ATOM   4224 C  C    . ASP A 1 295 ? -25.114 -6.893  57.057 1   35.722  ? 284 ASP A C    1 
ATOM   4225 O  O    . ASP A 1 295 ? -25.673 -6.577  56.002 1   40.641  ? 284 ASP A O    1 
ATOM   4226 C  CB   . ASP A 1 295 ? -24.805 -9.38   57.197 1   34.492  ? 284 ASP A CB   1 
ATOM   4227 C  CG   . ASP A 1 295 ? -24.179 -10.512 56.367 1   41.056  ? 284 ASP A CG   1 
ATOM   4228 O  OD1  . ASP A 1 295 ? -23.199 -10.267 55.657 1   40.088  ? 284 ASP A OD1  1 
ATOM   4229 O  OD2  . ASP A 1 295 ? -24.653 -11.63  56.435 1   43.088  ? 284 ASP A OD2  1 
ATOM   4230 H  H    . ASP A 1 295 ? -22.849 -8.407  58.633 1   36.776  ? 284 ASP A H    1 
ATOM   4231 H  HA   . ASP A 1 295 ? -23.749 -8.066  56.126 1   35.5    ? 284 ASP A HA   1 
ATOM   4232 H  HB2  . ASP A 1 295 ? -24.777 -9.643  58.141 1   35.894  ? 284 ASP A HB2  1 
ATOM   4233 H  HB3  . ASP A 1 295 ? -25.745 -9.294  56.935 1   35.885  ? 284 ASP A HB3  1 
ATOM   4234 N  N    . SER A 1 296 ? -25.241 -6.205  58.201 1   32.598  ? 285 SER A N    1 
ATOM   4235 C  CA   . SER A 1 296 ? -26.03  -4.989  58.256 1   30.071  ? 285 SER A CA   1 
ATOM   4236 C  C    . SER A 1 296 ? -25.515 -3.955  57.274 1   30.079  ? 285 SER A C    1 
ATOM   4237 O  O    . SER A 1 296 ? -26.279 -3.348  56.543 1   33.499  ? 285 SER A O    1 
ATOM   4238 C  CB   . SER A 1 296 ? -26.121 -4.429  59.664 1   28.399  ? 285 SER A CB   1 
ATOM   4239 O  OG   . SER A 1 296 ? -26.369 -5.485  60.567 1   31.641  ? 285 SER A OG   1 
ATOM   4240 H  H    . SER A 1 296 ? -24.823 -6.496  58.959 1   32.748  ? 285 SER A H    1 
ATOM   4241 H  HA   . SER A 1 296 ? -26.948 -5.226  57.971 1   30.347  ? 285 SER A HA   1 
ATOM   4242 H  HB2  . SER A 1 296 ? -25.285 -3.984  59.895 1   29.526  ? 285 SER A HB2  1 
ATOM   4243 H  HB3  . SER A 1 296 ? -26.846 -3.777  59.712 1   29.52   ? 285 SER A HB3  1 
ATOM   4244 H  HG   . SER A 1 296 ? -26.322 -5.22   61.389 0   31.19   ? 285 SER A HG   1 
ATOM   4245 N  N    . PHE A 1 297 ? -24.205 -3.678  57.337 1   34.343  ? 286 PHE A N    1 
ATOM   4246 C  CA   . PHE A 1 297 ? -23.611 -2.686  56.472 1   31.57   ? 286 PHE A CA   1 
ATOM   4247 C  C    . PHE A 1 297 ? -23.654 -3.156  55.01  1   31.709  ? 286 PHE A C    1 
ATOM   4248 O  O    . PHE A 1 297 ? -23.743 -2.309  54.117 1   31.099  ? 286 PHE A O    1 
ATOM   4249 C  CB   . PHE A 1 297 ? -22.183 -2.28   56.865 1   32.56   ? 286 PHE A CB   1 
ATOM   4250 C  CG   . PHE A 1 297 ? -22.114 -1.556  58.185 1   28.014  ? 286 PHE A CG   1 
ATOM   4251 C  CD1  . PHE A 1 297 ? -22.345 -0.188  58.233 1   30.572  ? 286 PHE A CD1  1 
ATOM   4252 C  CD2  . PHE A 1 297 ? -21.93  -2.281  59.366 1   29.561  ? 286 PHE A CD2  1 
ATOM   4253 C  CE1  . PHE A 1 297 ? -22.367 0.464   59.456 1   32.533  ? 286 PHE A CE1  1 
ATOM   4254 C  CE2  . PHE A 1 297 ? -21.902 -1.611  60.581 1   30.738  ? 286 PHE A CE2  1 
ATOM   4255 C  CZ   . PHE A 1 297 ? -22.114 -0.221  60.611 1   35.226  ? 286 PHE A CZ   1 
ATOM   4256 H  H    . PHE A 1 297 ? -23.674 -4.118  57.937 1   32.629  ? 286 PHE A H    1 
ATOM   4257 H  HA   . PHE A 1 297 ? -24.173 -1.868  56.535 1   32.295  ? 286 PHE A HA   1 
ATOM   4258 H  HB2  . PHE A 1 297 ? -21.628 -3.089  56.914 1   31.226  ? 286 PHE A HB2  1 
ATOM   4259 H  HB3  . PHE A 1 297 ? -21.816 -1.699  56.163 1   31.248  ? 286 PHE A HB3  1 
ATOM   4260 H  HD1  . PHE A 1 297 ? -22.514 0.29    57.436 1   30.447  ? 286 PHE A HD1  1 
ATOM   4261 H  HD2  . PHE A 1 297 ? -21.772 -3.21   59.331 1   29.561  ? 286 PHE A HD2  1 
ATOM   4262 H  HE1  . PHE A 1 297 ? -22.489 1.4     59.483 1   32.619  ? 286 PHE A HE1  1 
ATOM   4263 H  HE2  . PHE A 1 297 ? -21.749 -2.086  61.382 1   31.414  ? 286 PHE A HE2  1 
ATOM   4264 H  HZ   . PHE A 1 297 ? -22.111 0.237   61.437 1   33.422  ? 286 PHE A HZ   1 
ATOM   4265 N  N    . ARG A 1 298 ? -23.497 -4.47   54.761 1   30.422  ? 287 ARG A N    1 
ATOM   4266 C  CA   . ARG A 1 298 ? -23.604 -5.021  53.414 1   32.637  ? 287 ARG A CA   1 
ATOM   4267 C  C    . ARG A 1 298 ? -25.013 -4.731  52.87  1   36.398  ? 287 ARG A C    1 
ATOM   4268 O  O    . ARG A 1 298 ? -25.212 -4.256  51.755 1   36.33   ? 287 ARG A O    1 
ATOM   4269 C  CB   . ARG A 1 298 ? -23.31  -6.548  53.516 1   33.047  ? 287 ARG A CB   1 
ATOM   4270 C  CG   . ARG A 1 298 ? -23.058 -7.185  52.156 1   33.594  ? 287 ARG A CG   1 
ATOM   4271 C  CD   . ARG A 1 298 ? -22.9   -8.738  52.191 1   38.197  ? 287 ARG A CD   1 
ATOM   4272 N  NE   . ARG A 1 298 ? -21.89  -9.173  53.181 1   39.511  ? 287 ARG A NE   1 
ATOM   4273 C  CZ   . ARG A 1 298 ? -20.616 -9.18   52.913 1   41.307  ? 287 ARG A CZ   1 
ATOM   4274 N  NH1  . ARG A 1 298 ? -20.263 -8.807  51.715 1   34.399  ? 287 ARG A NH1  1 
ATOM   4275 N  NH2  . ARG A 1 298 ? -19.701 -9.626  53.756 1   40.727  ? 287 ARG A NH2  1 
ATOM   4276 H  H    . ARG A 1 298 ? -23.314 -5.037  55.454 1   31.264  ? 287 ARG A H    1 
ATOM   4277 H  HA   . ARG A 1 298 ? -22.931 -4.582  52.834 1   32.909  ? 287 ARG A HA   1 
ATOM   4278 H  HB2  . ARG A 1 298 ? -22.523 -6.687  54.084 1   33.116  ? 287 ARG A HB2  1 
ATOM   4279 H  HB3  . ARG A 1 298 ? -24.073 -6.995  53.941 1   33.122  ? 287 ARG A HB3  1 
ATOM   4280 H  HG2  . ARG A 1 298 ? -23.801 -6.958  51.556 1   34.45   ? 287 ARG A HG2  1 
ATOM   4281 H  HG3  . ARG A 1 298 ? -22.243 -6.795  51.77  1   34.453  ? 287 ARG A HG3  1 
ATOM   4282 H  HD2  . ARG A 1 298 ? -23.764 -9.137  52.419 1   37.433  ? 287 ARG A HD2  1 
ATOM   4283 H  HD3  . ARG A 1 298 ? -22.648 -9.061  51.303 1   37.461  ? 287 ARG A HD3  1 
ATOM   4284 H  HE   . ARG A 1 298 ? -22.157 -9.432  53.969 1   39.643  ? 287 ARG A HE   1 
ATOM   4285 H  HH11 . ARG A 1 298 ? -20.16  -7.947  51.535 1   36.4    ? 287 ARG A HH11 1 
ATOM   4286 H  HH12 . ARG A 1 298 ? -20.128 -9.415  51.088 1   36.479  ? 287 ARG A HH12 1 
ATOM   4287 H  HH21 . ARG A 1 298 ? -19.947 -9.964  54.534 1   40.871  ? 287 ARG A HH21 1 
ATOM   4288 H  HH22 . ARG A 1 298 ? -18.845 -9.583  53.538 1   40.846  ? 287 ARG A HH22 1 
ATOM   4289 N  N    . ALA A 1 299 ? -26.042 -5.049  53.66  1   39.375  ? 288 ALA A N    1 
ATOM   4290 C  CA   . ALA A 1 299 ? -27.427 -4.862  53.201 1   36.978  ? 288 ALA A CA   1 
ATOM   4291 C  C    . ALA A 1 299 ? -27.756 -3.386  52.995 1   39.716  ? 288 ALA A C    1 
ATOM   4292 O  O    . ALA A 1 299 ? -28.396 -3.014  52.009 1   39.687  ? 288 ALA A O    1 
ATOM   4293 C  CB   . ALA A 1 299 ? -28.396 -5.488  54.186 1   34.575  ? 288 ALA A CB   1 
ATOM   4294 H  H    . ALA A 1 299 ? -25.89  -5.39   54.495 1   37.986  ? 288 ALA A H    1 
ATOM   4295 H  HA   . ALA A 1 299 ? -27.524 -5.323  52.322 1   37.446  ? 288 ALA A HA   1 
ATOM   4296 H  HB1  . ALA A 1 299 ? -28.172 -6.425  54.315 1   35.279  ? 288 ALA A HB1  1 
ATOM   4297 H  HB2  . ALA A 1 299 ? -28.341 -5.024  55.039 1   35.279  ? 288 ALA A HB2  1 
ATOM   4298 H  HB3  . ALA A 1 299 ? -29.302 -5.419  53.842 1   35.311  ? 288 ALA A HB3  1 
ATOM   4299 N  N    . MET A 1 300 ? -27.254 -2.496  53.868 1   36.042  ? 289 MET A N    1 
ATOM   4300 C  CA   . MET A 1 300 ? -27.579 -1.076  53.679 1   34.602  ? 289 MET A CA   1 
ATOM   4301 C  C    . MET A 1 300 ? -26.949 -0.533  52.4   1   36.923  ? 289 MET A C    1 
ATOM   4302 O  O    . MET A 1 300 ? -27.537 0.367   51.787 1   37.886  ? 289 MET A O    1 
ATOM   4303 C  CB   . MET A 1 300 ? -27.255 -0.191  54.902 1   34.484  ? 289 MET A CB   1 
ATOM   4304 C  CG   . MET A 1 300 ? -28.027 -0.516  56.234 1   39.875  ? 289 MET A CG   1 
ATOM   4305 S  SD   . MET A 1 300 ? -27.699 0.801   57.44  1   45.944  ? 289 MET A SD   1 
ATOM   4306 C  CE   . MET A 1 300 ? -25.945 0.638   57.807 1   39.693  ? 289 MET A CE   1 
ATOM   4307 H  H    . MET A 1 300 ? -26.728 -2.758  54.568 1   36.579  ? 289 MET A H    1 
ATOM   4308 H  HA   . MET A 1 300 ? -28.559 -1.032  53.539 1   35.343  ? 289 MET A HA   1 
ATOM   4309 H  HB2  . MET A 1 300 ? -26.293 -0.258  55.078 1   35.694  ? 289 MET A HB2  1 
ATOM   4310 H  HB3  . MET A 1 300 ? -27.441 0.741   54.658 1   35.659  ? 289 MET A HB3  1 
ATOM   4311 H  HG2  . MET A 1 300 ? -28.988 -0.569  56.061 1   39.609  ? 289 MET A HG2  1 
ATOM   4312 H  HG3  . MET A 1 300 ? -27.728 -1.372  56.596 1   39.574  ? 289 MET A HG3  1 
ATOM   4313 H  HE1  . MET A 1 300 ? -25.705 1.254   58.524 1   41.158  ? 289 MET A HE1  1 
ATOM   4314 H  HE2  . MET A 1 300 ? -25.755 -0.276  58.086 1   41.158  ? 289 MET A HE2  1 
ATOM   4315 H  HE3  . MET A 1 300 ? -25.426 0.85    57.009 1   41.127  ? 289 MET A HE3  1 
ATOM   4316 N  N    . THR A 1 301 ? -25.737 -1.022  52.074 1   32.286  ? 290 THR A N    1 
ATOM   4317 C  CA   . THR A 1 301 ? -25.016 -0.593  50.891 1   38.041  ? 290 THR A CA   1 
ATOM   4318 C  C    . THR A 1 301 ? -25.804 -1.05   49.651 1   36.763  ? 290 THR A C    1 
ATOM   4319 O  O    . THR A 1 301 ? -26.004 -0.26   48.73  1   38.12   ? 290 THR A O    1 
ATOM   4320 C  CB   . THR A 1 301 ? -23.567 -1.123  50.866 1   39.782  ? 290 THR A CB   1 
ATOM   4321 O  OG1  . THR A 1 301 ? -22.972 -0.683  52.071 1   37.682  ? 290 THR A OG1  1 
ATOM   4322 C  CG2  . THR A 1 301 ? -22.733 -0.556  49.722 1   31.803  ? 290 THR A CG2  1 
ATOM   4323 H  H    . THR A 1 301 ? -25.347 -1.643  52.619 1   34.639  ? 290 THR A H    1 
ATOM   4324 H  HA   . THR A 1 301 ? -24.984 0.388   50.894 1   36.92   ? 290 THR A HA   1 
ATOM   4325 H  HB   . THR A 1 301 ? -23.563 -2.109  50.832 1   37.486  ? 290 THR A HB   1 
ATOM   4326 H  HG1  . THR A 1 301 ? -23.036 0.252   52.134 0   37.88   ? 290 THR A HG1  1 
ATOM   4327 H  HG21 . THR A 1 301 ? -21.799 -0.785  49.856 1   33.978  ? 290 THR A HG21 1 
ATOM   4328 H  HG22 . THR A 1 301 ? -22.828 0.412   49.699 1   33.977  ? 290 THR A HG22 1 
ATOM   4329 H  HG23 . THR A 1 301 ? -23.04  -0.93   48.879 1   33.987  ? 290 THR A HG23 1 
ATOM   4330 N  N    . GLU A 1 302 ? -26.177 -2.335  49.603 1   35.564  ? 291 GLU A N    1 
ATOM   4331 C  CA   . GLU A 1 302 ? -27.057 -2.912  48.591 1   40.761  ? 291 GLU A CA   1 
ATOM   4332 C  C    . GLU A 1 302 ? -28.296 -2.04   48.341 1   43.112  ? 291 GLU A C    1 
ATOM   4333 O  O    . GLU A 1 302 ? -28.6   -1.698  47.205 1   42.762  ? 291 GLU A O    1 
ATOM   4334 C  CB   . GLU A 1 302 ? -27.476 -4.33   49.013 1   42.539  ? 291 GLU A CB   1 
ATOM   4335 C  CG   . GLU A 1 302 ? -26.451 -5.362  48.52  1   51.327  ? 291 GLU A CG   1 
ATOM   4336 C  CD   . GLU A 1 302 ? -26.263 -6.747  49.186 1   72.12   ? 291 GLU A CD   1 
ATOM   4337 O  OE1  . GLU A 1 302 ? -27.142 -7.141  50.029 1   58.995  ? 291 GLU A OE1  1 
ATOM   4338 O  OE2  . GLU A 1 302 ? -25.167 -7.401  48.895 1   66      ? 291 GLU A OE2  1 
ATOM   4339 H  H    . GLU A 1 302 ? -25.848 -2.894  50.247 1   37.035  ? 291 GLU A H    1 
ATOM   4340 H  HA   . GLU A 1 302 ? -26.548 -2.975  47.743 1   40.535  ? 291 GLU A HA   1 
ATOM   4341 H  HB2  . GLU A 1 302 ? -27.549 -4.37   49.988 1   43.817  ? 291 GLU A HB2  1 
ATOM   4342 H  HB3  . GLU A 1 302 ? -28.357 -4.532  48.635 1   43.923  ? 291 GLU A HB3  1 
ATOM   4343 H  HG2  . GLU A 1 302 ? -26.643 -5.529  47.573 1   53.132  ? 291 GLU A HG2  1 
ATOM   4344 H  HG3  . GLU A 1 302 ? -25.573 -4.926  48.531 1   52.991  ? 291 GLU A HG3  1 
ATOM   4345 N  N    . GLN A 1 303 ? -29.008 -1.668  49.395 1   36.815  ? 292 GLN A N    1 
ATOM   4346 C  CA   . GLN A 1 303 ? -30.217 -0.9    49.244 1   43.589  ? 292 GLN A CA   1 
ATOM   4347 C  C    . GLN A 1 303 ? -29.893 0.447   48.636 1   47.496  ? 292 GLN A C    1 
ATOM   4348 O  O    . GLN A 1 303 ? -30.699 0.957   47.881 1   46.087  ? 292 GLN A O    1 
ATOM   4349 C  CB   . GLN A 1 303 ? -30.937 -0.557  50.543 1   44.47   ? 292 GLN A CB   1 
ATOM   4350 C  CG   . GLN A 1 303 ? -31.628 -1.742  51.203 1   48.504  ? 292 GLN A CG   1 
ATOM   4351 C  CD   . GLN A 1 303 ? -32.432 -1.313  52.427 1   61.964  ? 292 GLN A CD   1 
ATOM   4352 O  OE1  . GLN A 1 303 ? -32.245 -1.77   53.571 1   61.037  ? 292 GLN A OE1  1 
ATOM   4353 N  NE2  . GLN A 1 303 ? -33.367 -0.403  52.185 1   67.373  ? 292 GLN A NE2  1 
ATOM   4354 H  H    . GLN A 1 303 ? -28.733 -1.902  50.234 1   39.729  ? 292 GLN A H    1 
ATOM   4355 H  HA   . GLN A 1 303 ? -30.832 -1.389  48.641 1   43.012  ? 292 GLN A HA   1 
ATOM   4356 H  HB2  . GLN A 1 303 ? -30.285 -0.181  51.171 1   45.208  ? 292 GLN A HB2  1 
ATOM   4357 H  HB3  . GLN A 1 303 ? -31.604 0.136   50.358 1   45.38   ? 292 GLN A HB3  1 
ATOM   4358 H  HG2  . GLN A 1 303 ? -32.23  -2.17   50.557 1   50.28   ? 292 GLN A HG2  1 
ATOM   4359 H  HG3  . GLN A 1 303 ? -30.957 -2.403  51.474 1   50.231  ? 292 GLN A HG3  1 
ATOM   4360 H  HE21 . GLN A 1 303 ? -33.666 0.108   52.843 1   65.205  ? 292 GLN A HE21 1 
ATOM   4361 H  HE22 . GLN A 1 303 ? -33.695 -0.31   51.367 1   65.101  ? 292 GLN A HE22 1 
ATOM   4362 N  N    . VAL A 1 304 ? -28.744 1.053   48.937 1   42.035  ? 293 VAL A N    1 
ATOM   4363 C  CA   . VAL A 1 304 ? -28.605 2.413   48.409 1   34.777  ? 293 VAL A CA   1 
ATOM   4364 C  C    . VAL A 1 304 ? -28.002 2.314   47.009 1   38.287  ? 293 VAL A C    1 
ATOM   4365 O  O    . VAL A 1 304 ? -28.207 3.225   46.231 1   38.326  ? 293 VAL A O    1 
ATOM   4366 C  CB   . VAL A 1 304 ? -27.861 3.44    49.291 1   34.591  ? 293 VAL A CB   1 
ATOM   4367 C  CG1  . VAL A 1 304 ? -28.499 3.623   50.693 1   37.096  ? 293 VAL A CG1  1 
ATOM   4368 C  CG2  . VAL A 1 304 ? -26.418 2.965   49.555 1   39.22   ? 293 VAL A CG2  1 
ATOM   4369 H  H    . VAL A 1 304 ? -28.089 0.667   49.444 1   41.402  ? 293 VAL A H    1 
ATOM   4370 H  HA   . VAL A 1 304 ? -29.509 2.763   48.297 1   36.814  ? 293 VAL A HA   1 
ATOM   4371 H  HB   . VAL A 1 304 ? -27.846 4.303   48.815 1   35.882  ? 293 VAL A HB   1 
ATOM   4372 H  HG11 . VAL A 1 304 ? -28.577 2.758   51.129 1   36.366  ? 293 VAL A HG11 1 
ATOM   4373 H  HG12 . VAL A 1 304 ? -29.382 4.018   50.599 1   36.36   ? 293 VAL A HG12 1 
ATOM   4374 H  HG13 . VAL A 1 304 ? -27.94  4.207   51.232 1   36.38   ? 293 VAL A HG13 1 
ATOM   4375 H  HG21 . VAL A 1 304 ? -25.968 3.6     50.136 1   37.828  ? 293 VAL A HG21 1 
ATOM   4376 H  HG22 . VAL A 1 304 ? -25.936 2.901   48.714 1   37.826  ? 293 VAL A HG22 1 
ATOM   4377 H  HG23 . VAL A 1 304 ? -26.436 2.093   49.984 1   37.86   ? 293 VAL A HG23 1 
ATOM   4378 N  N    . GLN A 1 305 ? -27.188 1.29    46.731 1   36.803  ? 294 GLN A N    1 
ATOM   4379 C  CA   . GLN A 1 305 ? -26.706 1.017   45.385 1   44.538  ? 294 GLN A CA   1 
ATOM   4380 C  C    . GLN A 1 305 ? -27.92  0.78    44.484 1   44.817  ? 294 GLN A C    1 
ATOM   4381 O  O    . GLN A 1 305 ? -27.979 1.296   43.372 1   41.4    ? 294 GLN A O    1 
ATOM   4382 C  CB   . GLN A 1 305 ? -25.698 -0.13   45.233 1   44.94   ? 294 GLN A CB   1 
ATOM   4383 C  CG   . GLN A 1 305 ? -25.218 -0.398  43.805 1   54.514  ? 294 GLN A CG   1 
ATOM   4384 C  CD   . GLN A 1 305 ? -24.445 0.779   43.238 1   72.909  ? 294 GLN A CD   1 
ATOM   4385 O  OE1  . GLN A 1 305 ? -23.318 1.047   43.667 1   65.154  ? 294 GLN A OE1  1 
ATOM   4386 N  NE2  . GLN A 1 305 ? -25.02  1.538   42.312 1   60.438  ? 294 GLN A NE2  1 
ATOM   4387 H  H    . GLN A 1 305 ? -26.913 0.743   47.41  1   38.806  ? 294 GLN A H    1 
ATOM   4388 H  HA   . GLN A 1 305 ? -26.255 1.838   45.064 1   43.109  ? 294 GLN A HA   1 
ATOM   4389 H  HB2  . GLN A 1 305 ? -24.918 0.07    45.792 1   46.868  ? 294 GLN A HB2  1 
ATOM   4390 H  HB3  . GLN A 1 305 ? -26.107 -0.948  45.584 1   46.868  ? 294 GLN A HB3  1 
ATOM   4391 H  HG2  . GLN A 1 305 ? -24.639 -1.19   43.8   1   55.802  ? 294 GLN A HG2  1 
ATOM   4392 H  HG3  . GLN A 1 305 ? -25.989 -0.587  43.228 1   55.79   ? 294 GLN A HG3  1 
ATOM   4393 H  HE21 . GLN A 1 305 ? -24.554 2.183   41.918 1   64.01   ? 294 GLN A HE21 1 
ATOM   4394 H  HE22 . GLN A 1 305 ? -25.867 1.403   42.088 1   63.891  ? 294 GLN A HE22 1 
ATOM   4395 N  N    . GLN A 1 306 ? -28.882 -0.009  44.944 1   46.683  ? 295 GLN A N    1 
ATOM   4396 C  CA   . GLN A 1 306 ? -30.032 -0.314  44.091 1   50.517  ? 295 GLN A CA   1 
ATOM   4397 C  C    . GLN A 1 306 ? -30.841 0.943   43.791 1   47.459  ? 295 GLN A C    1 
ATOM   4398 O  O    . GLN A 1 306 ? -31.187 1.194   42.65  1   51.336  ? 295 GLN A O    1 
ATOM   4399 C  CB   . GLN A 1 306 ? -30.88  -1.38   44.741 1   46.581  ? 295 GLN A CB   1 
ATOM   4400 C  CG   . GLN A 1 306 ? -30.22  -2.734  44.564 1   56.618  ? 295 GLN A CG   1 
ATOM   4401 C  CD   . GLN A 1 306 ? -30.876 -3.745  45.472 1   61.999  ? 295 GLN A CD   1 
ATOM   4402 O  OE1  . GLN A 1 306 ? -32.06  -3.608  45.791 1   63.367  ? 295 GLN A OE1  1 
ATOM   4403 N  NE2  . GLN A 1 306 ? -30.093 -4.696  45.969 1   67.046  ? 295 GLN A NE2  1 
ATOM   4404 H  H    . GLN A 1 306 ? -28.832 -0.369  45.782 1   46.971  ? 295 GLN A H    1 
ATOM   4405 H  HA   . GLN A 1 306 ? -29.69  -0.674  43.233 1   48.45   ? 295 GLN A HA   1 
ATOM   4406 H  HB2  . GLN A 1 306 ? -30.983 -1.183  45.696 1   49.741  ? 295 GLN A HB2  1 
ATOM   4407 H  HB3  . GLN A 1 306 ? -31.769 -1.391  44.33  1   49.791  ? 295 GLN A HB3  1 
ATOM   4408 H  HG2  . GLN A 1 306 ? -30.305 -3.026  43.631 1   55.294  ? 295 GLN A HG2  1 
ATOM   4409 H  HG3  . GLN A 1 306 ? -29.265 -2.67   44.779 1   55.275  ? 295 GLN A HG3  1 
ATOM   4410 H  HE21 . GLN A 1 306 ? -30.333 -5.124  46.708 1   65.408  ? 295 GLN A HE21 1 
ATOM   4411 H  HE22 . GLN A 1 306 ? -29.332 -4.903  45.562 1   65.293  ? 295 GLN A HE22 1 
ATOM   4412 N  N    . ALA A 1 307 ? -30.991 1.803   44.793 1   42.789  ? 296 ALA A N    1 
ATOM   4413 C  CA   . ALA A 1 307 ? -31.681 3.074   44.625 1   43.939  ? 296 ALA A CA   1 
ATOM   4414 C  C    . ALA A 1 307 ? -30.996 3.917   43.585 1   47.742  ? 296 ALA A C    1 
ATOM   4415 O  O    . ALA A 1 307 ? -31.638 4.517   42.743 1   53.333  ? 296 ALA A O    1 
ATOM   4416 C  CB   . ALA A 1 307 ? -31.727 3.82    45.903 1   44.936  ? 296 ALA A CB   1 
ATOM   4417 H  H    . ALA A 1 307 ? -30.659 1.592   45.618 1   44.185  ? 296 ALA A H    1 
ATOM   4418 H  HA   . ALA A 1 307 ? -32.611 2.889   44.317 1   44.778  ? 296 ALA A HA   1 
ATOM   4419 H  HB1  . ALA A 1 307 ? -32.185 3.289   46.576 1   44.64   ? 296 ALA A HB1  1 
ATOM   4420 H  HB2  . ALA A 1 307 ? -30.822 4.009   46.204 1   44.653  ? 296 ALA A HB2  1 
ATOM   4421 H  HB3  . ALA A 1 307 ? -32.204 4.658   45.776 1   44.653  ? 296 ALA A HB3  1 
ATOM   4422 N  N    . ALA A 1 308 ? -29.669 3.942   43.675 1   48.678  ? 297 ALA A N    1 
ATOM   4423 C  CA   . ALA A 1 308 ? -28.866 4.706   42.757 1   48.482  ? 297 ALA A CA   1 
ATOM   4424 C  C    . ALA A 1 308 ? -29.02  4.169   41.331 1   43.975  ? 297 ALA A C    1 
ATOM   4425 O  O    . ALA A 1 308 ? -28.91  4.977   40.39  1   44.915  ? 297 ALA A O    1 
ATOM   4426 C  CB   . ALA A 1 308 ? -27.421 4.675   43.214 1   48.117  ? 297 ALA A CB   1 
ATOM   4427 H  H    . ALA A 1 308 ? -29.253 3.472   44.339 1   48.332  ? 297 ALA A H    1 
ATOM   4428 H  HA   . ALA A 1 308 ? -29.191 5.649   42.77  1   47.638  ? 297 ALA A HA   1 
ATOM   4429 H  HB1  . ALA A 1 308 ? -27.36  5.001   44.127 1   48.215  ? 297 ALA A HB1  1 
ATOM   4430 H  HB2  . ALA A 1 308 ? -27.085 3.764   43.175 1   48.183  ? 297 ALA A HB2  1 
ATOM   4431 H  HB3  . ALA A 1 308 ? -26.882 5.24    42.635 1   48.215  ? 297 ALA A HB3  1 
ATOM   4432 N  N    . ASP A 1 309 ? -29.13  2.824   41.195 1   41.408  ? 298 ASP A N    1 
ATOM   4433 C  CA   . ASP A 1 309 ? -29.378 2.16    39.907 1   50.368  ? 298 ASP A CA   1 
ATOM   4434 C  C    . ASP A 1 309 ? -30.692 2.699   39.309 1   49.812  ? 298 ASP A C    1 
ATOM   4435 O  O    . ASP A 1 309 ? -30.704 3.13    38.154 1   57.048  ? 298 ASP A O    1 
ATOM   4436 C  CB   . ASP A 1 309 ? -29.311 0.637   40.013 1   49.064  ? 298 ASP A CB   1 
ATOM   4437 C  CG   . ASP A 1 309 ? -27.903 0.041   40.108 1   63.089  ? 298 ASP A CG   1 
ATOM   4438 O  OD1  . ASP A 1 309 ? -26.925 0.773   39.828 1   60.886  ? 298 ASP A OD1  1 
ATOM   4439 O  OD2  . ASP A 1 309 ? -27.767 -1.16   40.427 1   58.248  ? 298 ASP A OD2  1 
ATOM   4440 H  H    . ASP A 1 309 ? -29.036 2.3     41.938 1   44.061  ? 298 ASP A H    1 
ATOM   4441 H  HA   . ASP A 1 309 ? -28.652 2.421   39.297 1   48.333  ? 298 ASP A HA   1 
ATOM   4442 H  HB2  . ASP A 1 309 ? -29.813 0.349   40.802 1   52.227  ? 298 ASP A HB2  1 
ATOM   4443 H  HB3  . ASP A 1 309 ? -29.748 0.251   39.225 1   52.265  ? 298 ASP A HB3  1 
ATOM   4444 N  N    . ARG A 1 310 ? -31.723 2.816   40.156 1   43.99   ? 299 ARG A N    1 
ATOM   4445 C  CA   . ARG A 1 310 ? -33.048 3.256   39.756 1   49.452  ? 299 ARG A CA   1 
ATOM   4446 C  C    . ARG A 1 310 ? -33.102 4.758   39.517 1   50.677  ? 299 ARG A C    1 
ATOM   4447 O  O    . ARG A 1 310 ? -33.855 5.159   38.682 1   52.124  ? 299 ARG A O    1 
ATOM   4448 C  CB   . ARG A 1 310 ? -34.155 2.873   40.736 1   46.499  ? 299 ARG A CB   1 
ATOM   4449 C  CG   . ARG A 1 310 ? -34.36  1.356   40.774 1   55.268  ? 299 ARG A CG   1 
ATOM   4450 C  CD   . ARG A 1 310 ? -35.493 0.863   41.703 1   61.003  ? 299 ARG A CD   1 
ATOM   4451 N  NE   . ARG A 1 310 ? -35.52  1.528   43.025 1   70.797  ? 299 ARG A NE   1 
ATOM   4452 C  CZ   . ARG A 1 310 ? -34.899 1.059   44.128 1   66.025  ? 299 ARG A CZ   1 
ATOM   4453 N  NH1  . ARG A 1 310 ? -34.257 -0.105  44.102 1   71.466  ? 299 ARG A NH1  1 
ATOM   4454 N  NH2  . ARG A 1 310 ? -34.861 1.767   45.243 1   64.293  ? 299 ARG A NH2  1 
ATOM   4455 H  H    . ARG A 1 310 ? -31.59  2.601   41.034 1   46.523  ? 299 ARG A H    1 
ATOM   4456 H  HA   . ARG A 1 310 ? -33.261 2.81    38.897 1   48.119  ? 299 ARG A HA   1 
ATOM   4457 H  HB2  . ARG A 1 310 ? -33.92  3.191   41.634 1   49.131  ? 299 ARG A HB2  1 
ATOM   4458 H  HB3  . ARG A 1 310 ? -34.994 3.306   40.468 1   49.063  ? 299 ARG A HB3  1 
ATOM   4459 H  HG2  . ARG A 1 310 ? -34.546 1.042   39.862 1   54.283  ? 299 ARG A HG2  1 
ATOM   4460 H  HG3  . ARG A 1 310 ? -33.519 0.934   41.056 1   54.317  ? 299 ARG A HG3  1 
ATOM   4461 H  HD2  . ARG A 1 310 ? -36.349 1.016   41.254 1   61.816  ? 299 ARG A HD2  1 
ATOM   4462 H  HD3  . ARG A 1 310 ? -35.396 -0.102  41.83  1   61.874  ? 299 ARG A HD3  1 
ATOM   4463 H  HE   . ARG A 1 310 ? -35.967 2.272   43.098 1   67.261  ? 299 ARG A HE   1 
ATOM   4464 H  HH11 . ARG A 1 310 ? -33.62  -0.242  43.505 1   69.494  ? 299 ARG A HH11 1 
ATOM   4465 H  HH12 . ARG A 1 310 ? -34.47  -0.737  44.683 1   69.686  ? 299 ARG A HH12 1 
ATOM   4466 H  HH21 . ARG A 1 310 ? -35.129 2.609   45.24  1   64.899  ? 299 ARG A HH21 1 
ATOM   4467 H  HH22 . ARG A 1 310 ? -34.566 1.395   45.989 1   64.906  ? 299 ARG A HH22 1 
ATOM   4468 N  N    . LEU A 1 311 ? -32.268 5.577   40.142 1   50.009  ? 300 LEU A N    1 
ATOM   4469 C  CA   . LEU A 1 311 ? -32.519 7.011   40.186 1   49.091  ? 300 LEU A CA   1 
ATOM   4470 C  C    . LEU A 1 311 ? -31.444 7.802   39.451 1   44.237  ? 300 LEU A C    1 
ATOM   4471 O  O    . LEU A 1 311 ? -31.748 8.872   38.954 1   49      ? 300 LEU A O    1 
ATOM   4472 C  CB   . LEU A 1 311 ? -32.722 7.578   41.605 1   46.779  ? 300 LEU A CB   1 
ATOM   4473 C  CG   . LEU A 1 311 ? -33.885 7.009   42.437 1   52.948  ? 300 LEU A CG   1 
ATOM   4474 C  CD1  . LEU A 1 311 ? -33.768 7.33    43.94  1   47.236  ? 300 LEU A CD1  1 
ATOM   4475 C  CD2  . LEU A 1 311 ? -35.263 7.501   41.974 1   51.833  ? 300 LEU A CD2  1 
ATOM   4476 H  H    . LEU A 1 311 ? -31.529 5.242   40.562 1   49.837  ? 300 LEU A H    1 
ATOM   4477 H  HA   . LEU A 1 311 ? -33.36  7.167   39.687 1   47.94   ? 300 LEU A HA   1 
ATOM   4478 H  HB2  . LEU A 1 311 ? -31.887 7.438   42.11  1   48.637  ? 300 LEU A HB2  1 
ATOM   4479 H  HB3  . LEU A 1 311 ? -32.848 8.552   41.528 1   48.617  ? 300 LEU A HB3  1 
ATOM   4480 H  HG   . LEU A 1 311 ? -33.872 6.022   42.34  1   50.47   ? 300 LEU A HG   1 
ATOM   4481 H  HD11 . LEU A 1 311 ? -32.959 6.926   44.296 1   48.844  ? 300 LEU A HD11 1 
ATOM   4482 H  HD12 . LEU A 1 311 ? -34.541 6.973   44.409 1   48.873  ? 300 LEU A HD12 1 
ATOM   4483 H  HD13 . LEU A 1 311 ? -33.731 8.293   44.065 1   48.844  ? 300 LEU A HD13 1 
ATOM   4484 H  HD21 . LEU A 1 311 ? -35.376 7.309   41.028 1   52.151  ? 300 LEU A HD21 1 
ATOM   4485 H  HD22 . LEU A 1 311 ? -35.331 8.46    42.118 1   52.151  ? 300 LEU A HD22 1 
ATOM   4486 H  HD23 . LEU A 1 311 ? -35.958 7.049   42.481 1   52.134  ? 300 LEU A HD23 1 
ATOM   4487 N  N    . CYS A 1 312 ? -30.176 7.405   39.451 1   47.764  ? 301 CYS A N    1 
ATOM   4488 C  CA   . CYS A 1 312 ? -29.144 8.318   38.934 1   39.865  ? 301 CYS A CA   1 
ATOM   4489 C  C    . CYS A 1 312 ? -28.061 7.56    38.2   1   44.756  ? 301 CYS A C    1 
ATOM   4490 O  O    . CYS A 1 312 ? -26.899 7.973   38.205 1   55.385  ? 301 CYS A O    1 
ATOM   4491 C  CB   . CYS A 1 312 ? -28.516 9.202   40.008 1   54.148  ? 301 CYS A CB   1 
ATOM   4492 S  SG   . CYS A 1 312 ? -28.316 8.435   41.65  1   51.049  ? 301 CYS A SG   1 
ATOM   4493 H  H    . CYS A 1 312 ? -29.936 6.587   39.781 1   45.208  ? 301 CYS A H    1 
ATOM   4494 H  HA   . CYS A 1 312 ? -29.579 8.924   38.281 1   44.666  ? 301 CYS A HA   1 
ATOM   4495 H  HB2  . CYS A 1 312 ? -27.631 9.499   39.7   1   49.702  ? 301 CYS A HB2  1 
ATOM   4496 H  HB3  . CYS A 1 312 ? -29.073 10.004  40.115 1   49.692  ? 301 CYS A HB3  1 
ATOM   4497 H  HG   . CYS A 1 312 ? -27.786 9.093   42.419 0   51.06   ? 301 CYS A HG   1 
ATOM   4498 N  N    . GLY A 1 313 ? -28.472 6.472   37.538 1   52.31   ? 302 GLY A N    1 
ATOM   4499 C  CA   . GLY A 1 313 ? -27.608 5.688   36.656 1   54.704  ? 302 GLY A CA   1 
ATOM   4500 C  C    . GLY A 1 313 ? -26.472 4.984   37.402 1   59.907  ? 302 GLY A C    1 
ATOM   4501 O  O    . GLY A 1 313 ? -25.388 4.822   36.83  1   46.199  ? 302 GLY A O    1 
ATOM   4502 H  H    . GLY A 1 313 ? -29.342 6.207   37.629 1   50.748  ? 302 GLY A H    1 
ATOM   4503 H  HA2  . GLY A 1 313 ? -28.157 5.014   36.191 1   55.233  ? 302 GLY A HA2  1 
ATOM   4504 H  HA3  . GLY A 1 313 ? -27.225 6.286   35.972 1   55.233  ? 302 GLY A HA3  1 
ATOM   4505 N  N    . GLY A 1 314 ? -26.764 4.605   38.666 1   49.637  ? 303 GLY A N    1 
ATOM   4506 C  CA   . GLY A 1 314 ? -25.848 3.921   39.583 1   58.445  ? 303 GLY A CA   1 
ATOM   4507 C  C    . GLY A 1 314 ? -24.8   4.799   40.309 1   51.433  ? 303 GLY A C    1 
ATOM   4508 O  O    . GLY A 1 314 ? -23.856 4.243   40.85  1   50.153  ? 303 GLY A O    1 
ATOM   4509 H  H    . GLY A 1 314 ? -27.606 4.782   38.974 1   53.751  ? 303 GLY A H    1 
ATOM   4510 H  HA2  . GLY A 1 314 ? -26.39  3.457   40.264 1   54.586  ? 303 GLY A HA2  1 
ATOM   4511 H  HA3  . GLY A 1 314 ? -25.371 3.225   39.073 1   54.627  ? 303 GLY A HA3  1 
ATOM   4512 N  N    . LYS A 1 315 ? -24.913 6.139   40.256 1   42.428  ? 304 LYS A N    1 
ATOM   4513 C  CA   . LYS A 1 315 ? -23.913 7.06    40.756 1   42.124  ? 304 LYS A CA   1 
ATOM   4514 C  C    . LYS A 1 315 ? -23.988 7.181   42.293 1   46.88   ? 304 LYS A C    1 
ATOM   4515 O  O    . LYS A 1 315 ? -24.914 7.753   42.875 1   38.796  ? 304 LYS A O    1 
ATOM   4516 C  CB   . LYS A 1 315 ? -24.128 8.416   40.092 1   42.101  ? 304 LYS A CB   1 
ATOM   4517 C  CG   . LYS A 1 315 ? -23.594 8.465   38.675 1   44.344  ? 304 LYS A CG   1 
ATOM   4518 C  CD   . LYS A 1 315 ? -23.841 9.876   38.127 1   53.234  ? 304 LYS A CD   1 
ATOM   4519 C  CE   . LYS A 1 315 ? -23.866 10.041  36.613 1   59.255  ? 304 LYS A CE   1 
ATOM   4520 N  NZ   . LYS A 1 315 ? -22.531 9.73    36.096 1   48.169  ? 304 LYS A NZ   1 
ATOM   4521 H  H    . LYS A 1 315 ? -25.672 6.491   39.887 1   44.428  ? 304 LYS A H    1 
ATOM   4522 H  HA   . LYS A 1 315 ? -23.018 6.719   40.5   1   43.016  ? 304 LYS A HA   1 
ATOM   4523 H  HB2  . LYS A 1 315 ? -25.087 8.622   40.078 1   42.745  ? 304 LYS A HB2  1 
ATOM   4524 H  HB3  . LYS A 1 315 ? -23.678 9.109   40.622 1   42.659  ? 304 LYS A HB3  1 
ATOM   4525 H  HG2  . LYS A 1 315 ? -22.632 8.268   38.678 1   45.654  ? 304 LYS A HG2  1 
ATOM   4526 H  HG3  . LYS A 1 315 ? -24.062 7.802   38.123 1   45.654  ? 304 LYS A HG3  1 
ATOM   4527 H  HD2  . LYS A 1 315 ? -24.698 10.197  38.484 1   52.189  ? 304 LYS A HD2  1 
ATOM   4528 H  HD3  . LYS A 1 315 ? -23.147 10.468  38.491 1   52.294  ? 304 LYS A HD3  1 
ATOM   4529 H  HE2  . LYS A 1 315 ? -24.518 9.434   36.218 1   55.08   ? 304 LYS A HE2  1 
ATOM   4530 H  HE3  . LYS A 1 315 ? -24.103 10.955  36.376 1   55.08   ? 304 LYS A HE3  1 
ATOM   4531 H  HZ1  . LYS A 1 315 ? -22.348 8.851   36.219 1   51.312  ? 304 LYS A HZ1  1 
ATOM   4532 H  HZ2  . LYS A 1 315 ? -21.908 10.228  36.526 1   51.354  ? 304 LYS A HZ2  1 
ATOM   4533 H  HZ3  . LYS A 1 315 ? -22.498 9.916   35.21  1   51.34   ? 304 LYS A HZ3  1 
ATOM   4534 N  N    . LEU A 1 316 ? -23.007 6.554   42.934 1   36.846  ? 305 LEU A N    1 
ATOM   4535 C  CA   . LEU A 1 316 ? -22.94  6.387   44.379 1   42.294  ? 305 LEU A CA   1 
ATOM   4536 C  C    . LEU A 1 316 ? -21.499 6.609   44.842 1   37.673  ? 305 LEU A C    1 
ATOM   4537 O  O    . LEU A 1 316 ? -20.588 5.947   44.356 1   37.394  ? 305 LEU A O    1 
ATOM   4538 C  CB   . LEU A 1 316 ? -23.441 4.986   44.718 1   42.139  ? 305 LEU A CB   1 
ATOM   4539 C  CG   . LEU A 1 316 ? -23.482 4.68    46.215 1   37.904  ? 305 LEU A CG   1 
ATOM   4540 C  CD1  . LEU A 1 316 ? -24.556 5.454   46.906 1   40.115  ? 305 LEU A CD1  1 
ATOM   4541 C  CD2  . LEU A 1 316 ? -23.652 3.193   46.422 1   43.847  ? 305 LEU A CD2  1 
ATOM   4542 H  H    . LEU A 1 316 ? -22.327 6.201   42.436 1   40.284  ? 305 LEU A H    1 
ATOM   4543 H  HA   . LEU A 1 316 ? -23.527 7.058   44.804 1   40.291  ? 305 LEU A HA   1 
ATOM   4544 H  HB2  . LEU A 1 316 ? -24.349 4.884   44.351 1   41.165  ? 305 LEU A HB2  1 
ATOM   4545 H  HB3  . LEU A 1 316 ? -22.851 4.331   44.278 1   41.191  ? 305 LEU A HB3  1 
ATOM   4546 H  HG   . LEU A 1 316 ? -22.612 4.945   46.611 1   40.131  ? 305 LEU A HG   1 
ATOM   4547 H  HD11 . LEU A 1 316 ? -24.334 6.4     46.897 1   39.46   ? 305 LEU A HD11 1 
ATOM   4548 H  HD12 . LEU A 1 316 ? -24.635 5.15    47.826 1   39.445  ? 305 LEU A HD12 1 
ATOM   4549 H  HD13 . LEU A 1 316 ? -25.402 5.317   46.447 1   39.454  ? 305 LEU A HD13 1 
ATOM   4550 H  HD21 . LEU A 1 316 ? -22.996 2.713   45.89  1   41.975  ? 305 LEU A HD21 1 
ATOM   4551 H  HD22 . LEU A 1 316 ? -24.546 2.928   46.15  1   41.993  ? 305 LEU A HD22 1 
ATOM   4552 H  HD23 . LEU A 1 316 ? -23.524 2.979   47.362 1   41.987  ? 305 LEU A HD23 1 
ATOM   4553 N  N    . VAL A 1 317 ? -21.313 7.589   45.733 1   42.372  ? 306 VAL A N    1 
ATOM   4554 C  CA   . VAL A 1 317 ? -20.073 7.776   46.461 1   33.288  ? 306 VAL A CA   1 
ATOM   4555 C  C    . VAL A 1 317 ? -20.293 7.597   47.963 1   35.774  ? 306 VAL A C    1 
ATOM   4556 O  O    . VAL A 1 317 ? -21.225 8.144   48.529 1   37.86   ? 306 VAL A O    1 
ATOM   4557 C  CB   . VAL A 1 317 ? -19.622 9.198   46.115 1   35.694  ? 306 VAL A CB   1 
ATOM   4558 C  CG1  . VAL A 1 317 ? -18.395 9.634   46.899 1   39.762  ? 306 VAL A CG1  1 
ATOM   4559 C  CG2  . VAL A 1 317 ? -19.287 9.347   44.637 1   38.917  ? 306 VAL A CG2  1 
ATOM   4560 H  H    . VAL A 1 317 ? -21.999 8.173   45.892 1   38.995  ? 306 VAL A H    1 
ATOM   4561 H  HA   . VAL A 1 317 ? -19.409 7.138   46.144 1   35.821  ? 306 VAL A HA   1 
ATOM   4562 H  HB   . VAL A 1 317 ? -20.366 9.808   46.332 1   36.574  ? 306 VAL A HB   1 
ATOM   4563 H  HG11 . VAL A 1 317 ? -17.724 8.931   46.868 1   38.51   ? 306 VAL A HG11 1 
ATOM   4564 H  HG12 . VAL A 1 317 ? -18.642 9.804   47.823 1   38.499  ? 306 VAL A HG12 1 
ATOM   4565 H  HG13 . VAL A 1 317 ? -18.031 10.446  46.509 1   38.509  ? 306 VAL A HG13 1 
ATOM   4566 H  HG21 . VAL A 1 317 ? -19.038 10.267  44.453 1   37.964  ? 306 VAL A HG21 1 
ATOM   4567 H  HG22 . VAL A 1 317 ? -20.063 9.111   44.101 1   37.971  ? 306 VAL A HG22 1 
ATOM   4568 H  HG23 . VAL A 1 317 ? -18.547 8.76    44.411 1   37.968  ? 306 VAL A HG23 1 
ATOM   4569 N  N    . MET A 1 318 ? -19.322 6.941   48.617 1   34.469  ? 307 MET A N    1 
ATOM   4570 C  CA   . MET A 1 318 ? -19.274 6.721   50.055 1   31.12   ? 307 MET A CA   1 
ATOM   4571 C  C    . MET A 1 318 ? -17.989 7.334   50.58  1   32.488  ? 307 MET A C    1 
ATOM   4572 O  O    . MET A 1 318 ? -16.926 7.228   49.96  1   37.041  ? 307 MET A O    1 
ATOM   4573 C  CB   . MET A 1 318 ? -19.358 5.216   50.384 1   33.793  ? 307 MET A CB   1 
ATOM   4574 C  CG   . MET A 1 318 ? -20.389 4.519   49.543 1   35.999  ? 307 MET A CG   1 
ATOM   4575 S  SD   . MET A 1 318 ? -20.812 2.827   49.978 1   42.435  ? 307 MET A SD   1 
ATOM   4576 C  CE   . MET A 1 318 ? -21.438 2.948   51.666 1   37.435  ? 307 MET A CE   1 
ATOM   4577 H  H    . MET A 1 318 ? -18.633 6.604   48.119 1   33.976  ? 307 MET A H    1 
ATOM   4578 H  HA   . MET A 1 318 ? -20.042 7.188   50.466 1   32.541  ? 307 MET A HA   1 
ATOM   4579 H  HB2  . MET A 1 318 ? -18.482 4.805   50.229 1   33.68   ? 307 MET A HB2  1 
ATOM   4580 H  HB3  . MET A 1 318 ? -19.583 5.109   51.332 1   33.712  ? 307 MET A HB3  1 
ATOM   4581 H  HG2  . MET A 1 318 ? -21.212 5.047   49.568 1   36.583  ? 307 MET A HG2  1 
ATOM   4582 H  HG3  . MET A 1 318 ? -20.079 4.517   48.616 1   36.574  ? 307 MET A HG3  1 
ATOM   4583 H  HE1  . MET A 1 318 ? -21.652 2.057   51.997 1   38.621  ? 307 MET A HE1  1 
ATOM   4584 H  HE2  . MET A 1 318 ? -20.758 3.352   52.235 1   38.58   ? 307 MET A HE2  1 
ATOM   4585 H  HE3  . MET A 1 318 ? -22.241 3.501   51.676 1   38.612  ? 307 MET A HE3  1 
ATOM   4586 N  N    . VAL A 1 319 ? -18.141 8.064   51.687 1   32.364  ? 308 VAL A N    1 
ATOM   4587 C  CA   . VAL A 1 319 ? -17.059 8.743   52.343 1   31.061  ? 308 VAL A CA   1 
ATOM   4588 C  C    . VAL A 1 319 ? -17.02  8.272   53.785 1   34.754  ? 308 VAL A C    1 
ATOM   4589 O  O    . VAL A 1 319 ? -17.999 8.389   54.489 1   28.792  ? 308 VAL A O    1 
ATOM   4590 C  CB   . VAL A 1 319 ? -17.263 10.264  52.337 1   38.703  ? 308 VAL A CB   1 
ATOM   4591 C  CG1  . VAL A 1 319 ? -16.072 10.958  52.959 1   39.523  ? 308 VAL A CG1  1 
ATOM   4592 C  CG2  . VAL A 1 319 ? -17.502 10.767  50.915 1   37.705  ? 308 VAL A CG2  1 
ATOM   4593 H  H    . VAL A 1 319 ? -18.977 8.137   52.051 1   32.103  ? 308 VAL A H    1 
ATOM   4594 H  HA   . VAL A 1 319 ? -16.216 8.524   51.901 1   33.334  ? 308 VAL A HA   1 
ATOM   4595 H  HB   . VAL A 1 319 ? -18.062 10.46   52.879 1   37.082  ? 308 VAL A HB   1 
ATOM   4596 H  HG11 . VAL A 1 319 ? -15.251 10.573  52.608 1   39.175  ? 308 VAL A HG11 1 
ATOM   4597 H  HG12 . VAL A 1 319 ? -16.096 10.844  53.923 1   39.245  ? 308 VAL A HG12 1 
ATOM   4598 H  HG13 . VAL A 1 319 ? -16.1   11.906  52.746 1   39.235  ? 308 VAL A HG13 1 
ATOM   4599 H  HG21 . VAL A 1 319 ? -17.462 11.738  50.901 1   38.025  ? 308 VAL A HG21 1 
ATOM   4600 H  HG22 . VAL A 1 319 ? -18.379 10.477  50.61  1   37.971  ? 308 VAL A HG22 1 
ATOM   4601 H  HG23 . VAL A 1 319 ? -16.82  10.407  50.323 1   37.997  ? 308 VAL A HG23 1 
ATOM   4602 N  N    . HIS A 1 320 ? -15.895 7.698   54.199 1   34.656  ? 309 HIS A N    1 
ATOM   4603 C  CA   . HIS A 1 320 ? -15.679 7.231   55.556 1   33.878  ? 309 HIS A CA   1 
ATOM   4604 C  C    . HIS A 1 320 ? -15.82  8.368   56.585 1   36.063  ? 309 HIS A C    1 
ATOM   4605 O  O    . HIS A 1 320 ? -15.289 9.495   56.454 1   36.581  ? 309 HIS A O    1 
ATOM   4606 C  CB   . HIS A 1 320 ? -14.255 6.661   55.632 1   35.287  ? 309 HIS A CB   1 
ATOM   4607 C  CG   . HIS A 1 320 ? -14.093 5.684   56.717 1   35.811  ? 309 HIS A CG   1 
ATOM   4608 N  ND1  . HIS A 1 320 ? -14.054 4.321   56.502 1   38.061  ? 309 HIS A ND1  1 
ATOM   4609 C  CD2  . HIS A 1 320 ? -13.906 5.868   58.027 1   38.12   ? 309 HIS A CD2  1 
ATOM   4610 C  CE1  . HIS A 1 320 ? -13.877 3.717   57.671 1   39.096  ? 309 HIS A CE1  1 
ATOM   4611 N  NE2  . HIS A 1 320 ? -13.825 4.625   58.618 1   34.814  ? 309 HIS A NE2  1 
ATOM   4612 H  H    . HIS A 1 320 ? -15.216 7.595   53.596 1   34.476  ? 309 HIS A H    1 
ATOM   4613 H  HA   . HIS A 1 320 ? -16.339 6.526   55.76  1   34.631  ? 309 HIS A HA   1 
ATOM   4614 H  HB2  . HIS A 1 320 ? -14.039 6.227   54.778 1   35.083  ? 309 HIS A HB2  1 
ATOM   4615 H  HB3  . HIS A 1 320 ? -13.622 7.4     55.768 1   35.093  ? 309 HIS A HB3  1 
ATOM   4616 H  HD1  . HIS A 1 320 ? -13.994 3.801   55.824 0   37.96   ? 309 HIS A HD1  1 
ATOM   4617 H  HD2  . HIS A 1 320 ? -13.898 6.69    58.477 1   36.978  ? 309 HIS A HD2  1 
ATOM   4618 H  HE1  . HIS A 1 320 ? -13.837 2.784   57.799 1   37.797  ? 309 HIS A HE1  1 
ATOM   4619 H  HE2  . HIS A 1 320 ? -13.741 4.434   59.557 0   34.34   ? 309 HIS A HE2  1 
ATOM   4620 N  N    . GLU A 1 321 ? -16.549 8.064   57.656 1   31.369  ? 310 GLU A N    1 
ATOM   4621 C  CA   . GLU A 1 321 ? -16.688 8.982   58.775 1   33.044  ? 310 GLU A CA   1 
ATOM   4622 C  C    . GLU A 1 321 ? -16.064 8.282   59.989 1   32.718  ? 310 GLU A C    1 
ATOM   4623 O  O    . GLU A 1 321 ? -14.852 8.131   60.03  1   34.048  ? 310 GLU A O    1 
ATOM   4624 C  CB   . GLU A 1 321 ? -18.177 9.379   58.818 1   36.06   ? 310 GLU A CB   1 
ATOM   4625 C  CG   . GLU A 1 321 ? -18.617 10.275  57.643 1   35.225  ? 310 GLU A CG   1 
ATOM   4626 C  CD   . GLU A 1 321 ? -18.083 11.73   57.591 1   50.389  ? 310 GLU A CD   1 
ATOM   4627 O  OE1  . GLU A 1 321 ? -17.631 12.267  58.683 1   43.863  ? 310 GLU A OE1  1 
ATOM   4628 O  OE2  . GLU A 1 321 ? -18.145 12.35   56.491 1   40.969  ? 310 GLU A OE2  1 
ATOM   4629 H  H    . GLU A 1 321 ? -16.975 7.256   57.696 1   32.831  ? 310 GLU A H    1 
ATOM   4630 H  HA   . GLU A 1 321 ? -16.158 9.796   58.583 1   33.271  ? 310 GLU A HA   1 
ATOM   4631 H  HB2  . GLU A 1 321 ? -18.721 8.564   58.807 1   35.14   ? 310 GLU A HB2  1 
ATOM   4632 H  HB3  . GLU A 1 321 ? -18.355 9.846   59.661 1   35.175  ? 310 GLU A HB3  1 
ATOM   4633 H  HG2  . GLU A 1 321 ? -18.361 9.833   56.806 1   38.371  ? 310 GLU A HG2  1 
ATOM   4634 H  HG3  . GLU A 1 321 ? -19.595 10.319  57.646 1   38.376  ? 310 GLU A HG3  1 
ATOM   4635 N  N    . GLY A 1 322 ? -16.901 7.774   60.883 1   30.939  ? 311 GLY A N    1 
ATOM   4636 C  CA   . GLY A 1 322 ? -16.53  7.242   62.175 1   30.224  ? 311 GLY A CA   1 
ATOM   4637 C  C    . GLY A 1 322 ? -16.468 5.701   62.193 1   29.682  ? 311 GLY A C    1 
ATOM   4638 O  O    . GLY A 1 322 ? -16.562 5.025   61.198 1   28.637  ? 311 GLY A O    1 
ATOM   4639 H  H    . GLY A 1 322 ? -17.787 7.749   60.662 1   31.286  ? 311 GLY A H    1 
ATOM   4640 H  HA2  . GLY A 1 322 ? -15.653 7.602   62.427 1   30.757  ? 311 GLY A HA2  1 
ATOM   4641 H  HA3  . GLY A 1 322 ? -17.184 7.55    62.846 1   30.39   ? 311 GLY A HA3  1 
ATOM   4642 N  N    . GLY A 1 323 ? -16.377 5.158   63.403 1   30.59   ? 312 GLY A N    1 
ATOM   4643 C  CA   . GLY A 1 323 ? -16.11  3.761   63.708 1   36.998  ? 312 GLY A CA   1 
ATOM   4644 C  C    . GLY A 1 323 ? -14.811 3.638   64.528 1   34.982  ? 312 GLY A C    1 
ATOM   4645 O  O    . GLY A 1 323 ? -13.774 3.946   63.982 1   33.644  ? 312 GLY A O    1 
ATOM   4646 H  H    . GLY A 1 323 ? -16.496 5.72    64.114 1   31.705  ? 312 GLY A H    1 
ATOM   4647 H  HA2  . GLY A 1 323 ? -16.864 3.385   64.216 1   34.849  ? 312 GLY A HA2  1 
ATOM   4648 H  HA3  . GLY A 1 323 ? -16.021 3.252   62.869 1   34.839  ? 312 GLY A HA3  1 
ATOM   4649 N  N    . TYR A 1 324 ? -14.916 3.158   65.784 1   35.844  ? 313 TYR A N    1 
ATOM   4650 C  CA   . TYR A 1 324 ? -13.856 3.13    66.78  1   36.34   ? 313 TYR A CA   1 
ATOM   4651 C  C    . TYR A 1 324 ? -13.496 1.678   67.153 1   34.212  ? 313 TYR A C    1 
ATOM   4652 O  O    . TYR A 1 324 ? -12.357 1.481   67.461 1   37.719  ? 313 TYR A O    1 
ATOM   4653 C  CB   . TYR A 1 324 ? -14.136 3.901   68.083 1   48.039  ? 313 TYR A CB   1 
ATOM   4654 C  CG   . TYR A 1 324 ? -12.938 4.096   69.053 1   53.489  ? 313 TYR A CG   1 
ATOM   4655 C  CD1  . TYR A 1 324 ? -12.219 5.317   69.1   1   75.344  ? 313 TYR A CD1  1 
ATOM   4656 C  CD2  . TYR A 1 324 ? -12.458 3.048   69.88  1   76.436  ? 313 TYR A CD2  1 
ATOM   4657 C  CE1  . TYR A 1 324 ? -11.112 5.501   69.931 1   71.07   ? 313 TYR A CE1  1 
ATOM   4658 C  CE2  . TYR A 1 324 ? -11.353 3.225   70.718 1   92.549  ? 313 TYR A CE2  1 
ATOM   4659 C  CZ   . TYR A 1 324 ? -10.682 4.452   70.739 1   99.871  ? 313 TYR A CZ   1 
ATOM   4660 O  OH   . TYR A 1 324 ? -9.588  4.659   71.535 1   110.352 ? 313 TYR A OH   1 
ATOM   4661 H  H    . TYR A 1 324 ? -15.731 2.83    66.034 1   35.668  ? 313 TYR A H    1 
ATOM   4662 H  HA   . TYR A 1 324 ? -13.051 3.538   66.365 1   37.701  ? 313 TYR A HA   1 
ATOM   4663 H  HB2  . TYR A 1 324 ? -14.49  4.786   67.844 1   46.223  ? 313 TYR A HB2  1 
ATOM   4664 H  HB3  . TYR A 1 324 ? -14.851 3.43    68.566 1   46.098  ? 313 TYR A HB3  1 
ATOM   4665 H  HD1  . TYR A 1 324 ? -12.497 6.032   68.551 1   68.964  ? 313 TYR A HD1  1 
ATOM   4666 H  HD2  . TYR A 1 324 ? -12.901 2.215   69.873 1   73.05   ? 313 TYR A HD2  1 
ATOM   4667 H  HE1  . TYR A 1 324 ? -10.66  6.324   69.947 1   77.89   ? 313 TYR A HE1  1 
ATOM   4668 H  HE2  . TYR A 1 324 ? -11.057 2.518   71.265 1   89.559  ? 313 TYR A HE2  1 
ATOM   4669 H  HH   . TYR A 1 324 ? -10.363 5.205   72.416 0   108.8   ? 313 TYR A HH   1 
ATOM   4670 N  N    . ALA A 1 325 ? -14.339 0.651   66.96  1   30.215  ? 314 ALA A N    1 
ATOM   4671 C  CA   . ALA A 1 325 ? -14.009 -0.773  67.2   1   30.321  ? 314 ALA A CA   1 
ATOM   4672 C  C    . ALA A 1 325 ? -12.865 -1.318  66.339 1   28.708  ? 314 ALA A C    1 
ATOM   4673 O  O    . ALA A 1 325 ? -13.025 -1.725  65.196 1   32.948  ? 314 ALA A O    1 
ATOM   4674 C  CB   . ALA A 1 325 ? -15.256 -1.614  67.042 1   33.581  ? 314 ALA A CB   1 
ATOM   4675 H  H    . ALA A 1 325 ? -15.181 0.844   66.664 1   31.236  ? 314 ALA A H    1 
ATOM   4676 H  HA   . ALA A 1 325 ? -13.717 -0.845  68.15  1   30.557  ? 314 ALA A HA   1 
ATOM   4677 H  HB1  . ALA A 1 325 ? -15.942 -1.298  67.652 1   32.58   ? 314 ALA A HB1  1 
ATOM   4678 H  HB2  . ALA A 1 325 ? -15.582 -1.546  66.129 1   32.58   ? 314 ALA A HB2  1 
ATOM   4679 H  HB3  . ALA A 1 325 ? -15.053 -2.543  67.24  1   32.581  ? 314 ALA A HB3  1 
ATOM   4680 N  N    . GLU A 1 326 ? -11.688 -1.447  66.934 1   28.767  ? 315 GLU A N    1 
ATOM   4681 C  CA   . GLU A 1 326 ? -10.455 -1.649  66.154 1   33.434  ? 315 GLU A CA   1 
ATOM   4682 C  C    . GLU A 1 326 ? -10.421 -3.015  65.488 1   33.307  ? 315 GLU A C    1 
ATOM   4683 O  O    . GLU A 1 326 ? -9.913  -3.222  64.398 1   38.1    ? 315 GLU A O    1 
ATOM   4684 C  CB   . GLU A 1 326 ? -9.279  -1.408  67.118 1   42.727  ? 315 GLU A CB   1 
ATOM   4685 C  CG   . GLU A 1 326 ? -7.915  -1.803  66.515 1   75.502  ? 315 GLU A CG   1 
ATOM   4686 C  CD   . GLU A 1 326 ? -6.53   -1.508  67.164 1   84.232  ? 315 GLU A CD   1 
ATOM   4687 O  OE1  . GLU A 1 326 ? -5.628  -2.41   67.227 1   72.658  ? 315 GLU A OE1  1 
ATOM   4688 O  OE2  . GLU A 1 326 ? -6.304  -0.318  67.513 1   70.5    ? 315 GLU A OE2  1 
ATOM   4689 H  H    . GLU A 1 326 ? -11.636 -1.414  67.846 1   29.93   ? 315 GLU A H    1 
ATOM   4690 H  HA   . GLU A 1 326 ? -10.421 -0.961  65.448 1   34.085  ? 315 GLU A HA   1 
ATOM   4691 H  HB2  . GLU A 1 326 ? -9.26   -0.46   67.365 1   46.07   ? 315 GLU A HB2  1 
ATOM   4692 H  HB3  . GLU A 1 326 ? -9.426  -1.928  67.936 1   45.969  ? 315 GLU A HB3  1 
ATOM   4693 H  HG2  . GLU A 1 326 ? -7.942  -2.772  66.368 1   67.456  ? 315 GLU A HG2  1 
ATOM   4694 H  HG3  . GLU A 1 326 ? -7.883  -1.416  65.614 1   67.664  ? 315 GLU A HG3  1 
ATOM   4695 N  N    . SER A 1 327 ? -10.992 -4.008  66.139 1   34.582  ? 316 SER A N    1 
ATOM   4696 C  CA   . SER A 1 327 ? -10.913 -5.335  65.563 1   32.829  ? 316 SER A CA   1 
ATOM   4697 C  C    . SER A 1 327 ? -12.157 -5.597  64.711 1   32.307  ? 316 SER A C    1 
ATOM   4698 O  O    . SER A 1 327 ? -12.136 -6.471  63.867 1   32.074  ? 316 SER A O    1 
ATOM   4699 C  CB   . SER A 1 327 ? -10.787 -6.323  66.707 1   29.828  ? 316 SER A CB   1 
ATOM   4700 O  OG   . SER A 1 327 ? -12.044 -6.403  67.365 1   35.53   ? 316 SER A OG   1 
ATOM   4701 H  H    . SER A 1 327 ? -11.423 -3.876  66.934 1   33.782  ? 316 SER A H    1 
ATOM   4702 H  HA   . SER A 1 327 ? -10.107 -5.397  64.992 1   32.529  ? 316 SER A HA   1 
ATOM   4703 H  HB2  . SER A 1 327 ? -10.536 -7.201  66.36  1   31.778  ? 316 SER A HB2  1 
ATOM   4704 H  HB3  . SER A 1 327 ? -10.102 -6.021  67.332 1   31.777  ? 316 SER A HB3  1 
ATOM   4705 H  HG   . SER A 1 327 ? -11.983 -6.962  68.011 0   35.3    ? 316 SER A HG   1 
ATOM   4706 N  N    . TYR A 1 328 ? -13.252 -4.823  64.876 1   31.787  ? 317 TYR A N    1 
ATOM   4707 C  CA   . TYR A 1 328 ? -14.488 -5.209  64.164 1   27.455  ? 317 TYR A CA   1 
ATOM   4708 C  C    . TYR A 1 328 ? -14.77  -4.341  62.933 1   34.186  ? 317 TYR A C    1 
ATOM   4709 O  O    . TYR A 1 328 ? -15.201 -4.851  61.932 1   32.533  ? 317 TYR A O    1 
ATOM   4710 C  CB   . TYR A 1 328 ? -15.703 -5.267  65.09  1   30.93   ? 317 TYR A CB   1 
ATOM   4711 C  CG   . TYR A 1 328 ? -16.87  -6.006  64.476 1   32.42   ? 317 TYR A CG   1 
ATOM   4712 C  CD1  . TYR A 1 328 ? -16.717 -7.245  63.901 1   33.596  ? 317 TYR A CD1  1 
ATOM   4713 C  CD2  . TYR A 1 328 ? -18.121 -5.425  64.383 1   33.983  ? 317 TYR A CD2  1 
ATOM   4714 C  CE1  . TYR A 1 328 ? -17.725 -7.842  63.173 1   33.57   ? 317 TYR A CE1  1 
ATOM   4715 C  CE2  . TYR A 1 328 ? -19.162 -6.047  63.72  1   34.09   ? 317 TYR A CE2  1 
ATOM   4716 C  CZ   . TYR A 1 328 ? -18.975 -7.275  63.131 1   36.451  ? 317 TYR A CZ   1 
ATOM   4717 O  OH   . TYR A 1 328 ? -19.995 -7.868  62.475 1   32.966  ? 317 TYR A OH   1 
ATOM   4718 H  H    . TYR A 1 328 ? -13.243 -4.082  65.411 1   30.942  ? 317 TYR A H    1 
ATOM   4719 H  HA   . TYR A 1 328 ? -14.344 -6.131  63.83  1   30.163  ? 317 TYR A HA   1 
ATOM   4720 H  HB2  . TYR A 1 328 ? -15.442 -5.716  65.925 1   30.438  ? 317 TYR A HB2  1 
ATOM   4721 H  HB3  . TYR A 1 328 ? -15.98  -4.349  65.306 1   30.469  ? 317 TYR A HB3  1 
ATOM   4722 H  HD1  . TYR A 1 328 ? -15.859 -7.639  63.89  1   33.258  ? 317 TYR A HD1  1 
ATOM   4723 H  HD2  . TYR A 1 328 ? -18.262 -4.571  64.758 1   33.555  ? 317 TYR A HD2  1 
ATOM   4724 H  HE1  . TYR A 1 328 ? -17.59  -8.695  62.808 1   34.225  ? 317 TYR A HE1  1 
ATOM   4725 H  HE2  . TYR A 1 328 ? -20.005 -5.63   63.674 1   34.534  ? 317 TYR A HE2  1 
ATOM   4726 H  HH   . TYR A 1 328 ? -20.423 -8.391  63.01  0   32.87   ? 317 TYR A HH   1 
ATOM   4727 N  N    . VAL A 1 329 ? -14.522 -3.022  62.981 1   31.411  ? 318 VAL A N    1 
ATOM   4728 C  CA   . VAL A 1 329 ? -14.744 -2.186  61.851 1   29.889  ? 318 VAL A CA   1 
ATOM   4729 C  C    . VAL A 1 329 ? -14.144 -2.77   60.588 1   32.338  ? 318 VAL A C    1 
ATOM   4730 O  O    . VAL A 1 329 ? -14.761 -2.586  59.559 1   29.037  ? 318 VAL A O    1 
ATOM   4731 C  CB   . VAL A 1 329 ? -14.225 -0.752  62.1   1   36.394  ? 318 VAL A CB   1 
ATOM   4732 C  CG1  . VAL A 1 329 ? -14.266 0.097   60.854 1   33.634  ? 318 VAL A CG1  1 
ATOM   4733 C  CG2  . VAL A 1 329 ? -15.019 -0.06   63.187 1   36.828  ? 318 VAL A CG2  1 
ATOM   4734 H  H    . VAL A 1 329 ? -14.198 -2.652  63.752 1   31.774  ? 318 VAL A H    1 
ATOM   4735 H  HA   . VAL A 1 329 ? -15.711 -2.129  61.718 1   31.732  ? 318 VAL A HA   1 
ATOM   4736 H  HB   . VAL A 1 329 ? -13.288 -0.823  62.397 1   34.62   ? 318 VAL A HB   1 
ATOM   4737 H  HG11 . VAL A 1 329 ? -15.104 -0.054  60.385 1   34.396  ? 318 VAL A HG11 1 
ATOM   4738 H  HG12 . VAL A 1 329 ? -13.523 -0.139  60.273 1   34.418  ? 318 VAL A HG12 1 
ATOM   4739 H  HG13 . VAL A 1 329 ? -14.198 1.036   61.097 1   34.449  ? 318 VAL A HG13 1 
ATOM   4740 H  HG21 . VAL A 1 329 ? -14.604 0.793   63.4   1   36.66   ? 318 VAL A HG21 1 
ATOM   4741 H  HG22 . VAL A 1 329 ? -15.039 -0.616  63.983 1   36.6    ? 318 VAL A HG22 1 
ATOM   4742 H  HG23 . VAL A 1 329 ? -15.928 0.092   62.878 1   36.672  ? 318 VAL A HG23 1 
ATOM   4743 N  N    . PRO A 1 330 ? -12.897 -3.307  60.515 1   29.547  ? 319 PRO A N    1 
ATOM   4744 C  CA   . PRO A 1 330 ? -12.429 -3.772  59.205 1   32.663  ? 319 PRO A CA   1 
ATOM   4745 C  C    . PRO A 1 330 ? -13.4   -4.74   58.513 1   32.524  ? 319 PRO A C    1 
ATOM   4746 O  O    . PRO A 1 330 ? -13.473 -4.788  57.29  1   32.821  ? 319 PRO A O    1 
ATOM   4747 C  CB   . PRO A 1 330 ? -11.093 -4.436  59.578 1   31.68   ? 319 PRO A CB   1 
ATOM   4748 C  CG   . PRO A 1 330 ? -10.63  -3.651  60.795 1   28.073  ? 319 PRO A CG   1 
ATOM   4749 C  CD   . PRO A 1 330 ? -11.933 -3.493  61.619 1   29.048  ? 319 PRO A CD   1 
ATOM   4750 H  HA   . PRO A 1 330 ? -12.261 -2.989  58.623 1   31.819  ? 319 PRO A HA   1 
ATOM   4751 H  HB2  . PRO A 1 330 ? -11.221 -5.388  59.8   1   31.047  ? 319 PRO A HB2  1 
ATOM   4752 H  HB3  . PRO A 1 330 ? -10.443 -4.363  58.842 1   31.051  ? 319 PRO A HB3  1 
ATOM   4753 H  HG2  . PRO A 1 330 ? -9.952  -4.147  61.3   1   29.084  ? 319 PRO A HG2  1 
ATOM   4754 H  HG3  . PRO A 1 330 ? -10.266 -2.778  60.537 1   29.072  ? 319 PRO A HG3  1 
ATOM   4755 H  HD2  . PRO A 1 330 ? -12.128 -4.301  62.142 1   28.991  ? 319 PRO A HD2  1 
ATOM   4756 H  HD3  . PRO A 1 330 ? -11.896 -2.707  62.208 1   28.989  ? 319 PRO A HD3  1 
ATOM   4757 N  N    . PHE A 1 331 ? -14.137 -5.557  59.281 1   30.841  ? 320 PHE A N    1 
ATOM   4758 C  CA   . PHE A 1 331 ? -15.014 -6.524  58.635 1   34.111  ? 320 PHE A CA   1 
ATOM   4759 C  C    . PHE A 1 331 ? -16.225 -5.807  58.042 1   31.446  ? 320 PHE A C    1 
ATOM   4760 O  O    . PHE A 1 331 ? -16.745 -6.205  56.995 1   31.79   ? 320 PHE A O    1 
ATOM   4761 C  CB   . PHE A 1 331 ? -15.411 -7.599  59.646 1   36.654  ? 320 PHE A CB   1 
ATOM   4762 C  CG   . PHE A 1 331 ? -14.26  -8.518  60.005 1   31.986  ? 320 PHE A CG   1 
ATOM   4763 C  CD1  . PHE A 1 331 ? -13.853 -9.509  59.133 1   33.103  ? 320 PHE A CD1  1 
ATOM   4764 C  CD2  . PHE A 1 331 ? -13.578 -8.377  61.196 1   29.38   ? 320 PHE A CD2  1 
ATOM   4765 C  CE1  . PHE A 1 331 ? -12.781 -10.301 59.436 1   33.98   ? 320 PHE A CE1  1 
ATOM   4766 C  CE2  . PHE A 1 331 ? -12.469 -9.153  61.486 1   31.963  ? 320 PHE A CE2  1 
ATOM   4767 C  CZ   . PHE A 1 331 ? -12.085 -10.127 60.601 1   34.999  ? 320 PHE A CZ   1 
ATOM   4768 H  H    . PHE A 1 331 ? -14.086 -5.525  60.192 1   31.983  ? 320 PHE A H    1 
ATOM   4769 H  HA   . PHE A 1 331 ? -14.512 -6.961  57.896 1   33.378  ? 320 PHE A HA   1 
ATOM   4770 H  HB2  . PHE A 1 331 ? -15.74  -7.161  60.462 1   34.869  ? 320 PHE A HB2  1 
ATOM   4771 H  HB3  . PHE A 1 331 ? -16.143 -8.134  59.267 1   34.919  ? 320 PHE A HB3  1 
ATOM   4772 H  HD1  . PHE A 1 331 ? -14.304 -9.623  58.311 1   33.053  ? 320 PHE A HD1  1 
ATOM   4773 H  HD2  . PHE A 1 331 ? -13.824 -7.683  61.787 1   30.693  ? 320 PHE A HD2  1 
ATOM   4774 H  HE1  . PHE A 1 331 ? -12.512 -10.971 58.829 1   33.959  ? 320 PHE A HE1  1 
ATOM   4775 H  HE2  . PHE A 1 331 ? -12.015 -9.047  62.307 1   32.049  ? 320 PHE A HE2  1 
ATOM   4776 H  HZ   . PHE A 1 331 ? -11.364 -10.698 60.81  1   33.975  ? 320 PHE A HZ   1 
ATOM   4777 N  N    . CYS A 1 332 ? -16.633 -4.731  58.721 1   30.534  ? 321 CYS A N    1 
ATOM   4778 C  CA   . CYS A 1 332 ? -17.788 -3.946  58.298 1   35.404  ? 321 CYS A CA   1 
ATOM   4779 C  C    . CYS A 1 332 ? -17.403 -3.187  57.03  1   39.298  ? 321 CYS A C    1 
ATOM   4780 O  O    . CYS A 1 332 ? -18.146 -3.149  56.081 1   30.884  ? 321 CYS A O    1 
ATOM   4781 C  CB   . CYS A 1 332 ? -18.275 -3.057  59.433 1   35.422  ? 321 CYS A CB   1 
ATOM   4782 S  SG   . CYS A 1 332 ? -18.801 -3.973  60.902 1   36.191  ? 321 CYS A SG   1 
ATOM   4783 H  H    . CYS A 1 332 ? -16.187 -4.481  59.478 1   31.824  ? 321 CYS A H    1 
ATOM   4784 H  HA   . CYS A 1 332 ? -18.517 -4.577  58.071 1   35.026  ? 321 CYS A HA   1 
ATOM   4785 H  HB2  . CYS A 1 332 ? -17.554 -2.44   59.691 1   35.562  ? 321 CYS A HB2  1 
ATOM   4786 H  HB3  . CYS A 1 332 ? -19.034 -2.519  59.115 1   35.561  ? 321 CYS A HB3  1 
ATOM   4787 H  HG   . CYS A 1 332 ? -19.106 -3.013  61.582 0   36.09   ? 321 CYS A HG   1 
ATOM   4788 N  N    . GLY A 1 333 ? -16.202 -2.623  57.009 1   30.721  ? 322 GLY A N    1 
ATOM   4789 C  CA   . GLY A 1 333 ? -15.698 -1.931  55.853 1   32.225  ? 322 GLY A CA   1 
ATOM   4790 C  C    . GLY A 1 333 ? -15.498 -2.858  54.662 1   32.757  ? 322 GLY A C    1 
ATOM   4791 O  O    . GLY A 1 333 ? -15.816 -2.497  53.552 1   33.002  ? 322 GLY A O    1 
ATOM   4792 H  H    . GLY A 1 333 ? -15.675 -2.666  57.755 1   32.933  ? 322 GLY A H    1 
ATOM   4793 H  HA2  . GLY A 1 333 ? -16.33  -1.217  55.608 1   32.016  ? 322 GLY A HA2  1 
ATOM   4794 H  HA3  . GLY A 1 333 ? -14.84  -1.508  56.085 1   32.02   ? 322 GLY A HA3  1 
ATOM   4795 N  N    . LEU A 1 334 ? -14.859 -4.002  54.862 1   30.807  ? 323 LEU A N    1 
ATOM   4796 C  CA   . LEU A 1 334 ? -14.697 -4.932  53.773 1   32.931  ? 323 LEU A CA   1 
ATOM   4797 C  C    . LEU A 1 334 ? -16.081 -5.272  53.226 1   35.09   ? 323 LEU A C    1 
ATOM   4798 O  O    . LEU A 1 334 ? -16.283 -5.338  52.012 1   32.694  ? 323 LEU A O    1 
ATOM   4799 C  CB   . LEU A 1 334 ? -14.019 -6.21   54.272 1   33.629  ? 323 LEU A CB   1 
ATOM   4800 C  CG   . LEU A 1 334 ? -13.802 -7.28   53.216 1   37.12   ? 323 LEU A CG   1 
ATOM   4801 C  CD1  . LEU A 1 334 ? -12.825 -6.749  52.143 1   36.122  ? 323 LEU A CD1  1 
ATOM   4802 C  CD2  . LEU A 1 334 ? -13.353 -8.542  53.908 1   37.754  ? 323 LEU A CD2  1 
ATOM   4803 H  H    . LEU A 1 334 ? -14.517 -4.206  55.684 1   31.745  ? 323 LEU A H    1 
ATOM   4804 H  HA   . LEU A 1 334 ? -14.149 -4.51   53.064 1   33.037  ? 323 LEU A HA   1 
ATOM   4805 H  HB2  . LEU A 1 334 ? -13.144 -5.966  54.654 1   34.256  ? 323 LEU A HB2  1 
ATOM   4806 H  HB3  . LEU A 1 334 ? -14.571 -6.59   54.994 1   34.277  ? 323 LEU A HB3  1 
ATOM   4807 H  HG   . LEU A 1 334 ? -14.671 -7.465  52.777 1   36.373  ? 323 LEU A HG   1 
ATOM   4808 H  HD11 . LEU A 1 334 ? -13.283 -6.107  51.575 1   36.36   ? 323 LEU A HD11 1 
ATOM   4809 H  HD12 . LEU A 1 334 ? -12.506 -7.489  51.601 1   36.392  ? 323 LEU A HD12 1 
ATOM   4810 H  HD13 . LEU A 1 334 ? -12.07  -6.317  52.576 1   36.368  ? 323 LEU A HD13 1 
ATOM   4811 H  HD21 . LEU A 1 334 ? -14.056 -8.856  54.501 1   37.532  ? 323 LEU A HD21 1 
ATOM   4812 H  HD22 . LEU A 1 334 ? -12.551 -8.361  54.426 1   37.522  ? 323 LEU A HD22 1 
ATOM   4813 H  HD23 . LEU A 1 334 ? -13.161 -9.226  53.244 1   37.55   ? 323 LEU A HD23 1 
ATOM   4814 N  N    . ALA A 1 335 ? -17.031 -5.556  54.106 1   30.624  ? 324 ALA A N    1 
ATOM   4815 C  CA   . ALA A 1 335 ? -18.398 -5.848  53.62  1   32.299  ? 324 ALA A CA   1 
ATOM   4816 C  C    . ALA A 1 335 ? -18.971 -4.76   52.71  1   34.933  ? 324 ALA A C    1 
ATOM   4817 O  O    . ALA A 1 335 ? -19.486 -5.023  51.619 1   38.376  ? 324 ALA A O    1 
ATOM   4818 C  CB   . ALA A 1 335 ? -19.306 -6.138  54.751 1   36.6    ? 324 ALA A CB   1 
ATOM   4819 H  H    . ALA A 1 335 ? -16.852 -5.581  55.002 1   32.041  ? 324 ALA A H    1 
ATOM   4820 H  HA   . ALA A 1 335 ? -18.334 -6.677  53.069 1   33.212  ? 324 ALA A HA   1 
ATOM   4821 H  HB1  . ALA A 1 335 ? -18.949 -6.875  55.276 1   35.231  ? 324 ALA A HB1  1 
ATOM   4822 H  HB2  . ALA A 1 335 ? -19.386 -5.352  55.316 1   35.212  ? 324 ALA A HB2  1 
ATOM   4823 H  HB3  . ALA A 1 335 ? -20.183 -6.381  54.412 1   35.219  ? 324 ALA A HB3  1 
ATOM   4824 N  N    . VAL A 1 336 ? -18.835 -3.507  53.105 1   32.432  ? 325 VAL A N    1 
ATOM   4825 C  CA   . VAL A 1 336 ? -19.287 -2.428  52.246 1   31.971  ? 325 VAL A CA   1 
ATOM   4826 C  C    . VAL A 1 336 ? -18.562 -2.477  50.922 1   30.149  ? 325 VAL A C    1 
ATOM   4827 O  O    . VAL A 1 336 ? -19.2   -2.282  49.905 1   38.188  ? 325 VAL A O    1 
ATOM   4828 C  CB   . VAL A 1 336 ? -19.101 -1.068  52.937 1   31.212  ? 325 VAL A CB   1 
ATOM   4829 C  CG1  . VAL A 1 336 ? -19.292 0.134   52.014 1   31.234  ? 325 VAL A CG1  1 
ATOM   4830 C  CG2  . VAL A 1 336 ? -20.047 -0.974  54.095 1   34.714  ? 325 VAL A CG2  1 
ATOM   4831 H  H    . VAL A 1 336 ? -18.455 -3.313  53.914 1   32.885  ? 325 VAL A H    1 
ATOM   4832 H  HA   . VAL A 1 336 ? -20.241 -2.556  52.077 1   31.684  ? 325 VAL A HA   1 
ATOM   4833 H  HB   . VAL A 1 336 ? -18.18  -1.04   53.289 1   31.999  ? 325 VAL A HB   1 
ATOM   4834 H  HG11 . VAL A 1 336 ? -20.074 -0.008  51.455 1   31.235  ? 325 VAL A HG11 1 
ATOM   4835 H  HG12 . VAL A 1 336 ? -18.507 0.241   51.451 1   31.231  ? 325 VAL A HG12 1 
ATOM   4836 H  HG13 . VAL A 1 336 ? -19.418 0.937   52.547 1   31.263  ? 325 VAL A HG13 1 
ATOM   4837 H  HG21 . VAL A 1 336 ? -19.957 -0.104  54.518 1   33.62   ? 325 VAL A HG21 1 
ATOM   4838 H  HG22 . VAL A 1 336 ? -19.842 -1.669  54.741 1   33.6    ? 325 VAL A HG22 1 
ATOM   4839 H  HG23 . VAL A 1 336 ? -20.959 -1.086  53.779 1   33.626  ? 325 VAL A HG23 1 
ATOM   4840 N  N    . MET A 1 337 ? -17.25  -2.658  50.925 1   31.591  ? 326 MET A N    1 
ATOM   4841 C  CA   . MET A 1 337 ? -16.501 -2.531  49.698 1   29.78   ? 326 MET A CA   1 
ATOM   4842 C  C    . MET A 1 337 ? -16.814 -3.719  48.792 1   32.99   ? 326 MET A C    1 
ATOM   4843 O  O    . MET A 1 337 ? -16.81  -3.598  47.565 1   36.504  ? 326 MET A O    1 
ATOM   4844 C  CB   . MET A 1 337 ? -14.978 -2.533  49.904 1   33.906  ? 326 MET A CB   1 
ATOM   4845 C  CG   . MET A 1 337 ? -14.367 -1.288  50.531 1   34.687  ? 326 MET A CG   1 
ATOM   4846 S  SD   . MET A 1 337 ? -14.944 0.184   49.627 1   38.247  ? 326 MET A SD   1 
ATOM   4847 C  CE   . MET A 1 337 ? -14.32  -0.354  48.01  1   35.505  ? 326 MET A CE   1 
ATOM   4848 H  H    . MET A 1 337 ? -16.81  -2.86   51.7   1   30.883  ? 326 MET A H    1 
ATOM   4849 H  HA   . MET A 1 337 ? -16.778 -1.698  49.241 1   31.477  ? 326 MET A HA   1 
ATOM   4850 H  HB2  . MET A 1 337 ? -14.754 -3.301  50.472 1   33.101  ? 326 MET A HB2  1 
ATOM   4851 H  HB3  . MET A 1 337 ? -14.551 -2.687  49.035 1   33.144  ? 326 MET A HB3  1 
ATOM   4852 H  HG2  . MET A 1 337 ? -14.634 -1.22   51.469 1   35.125  ? 326 MET A HG2  1 
ATOM   4853 H  HG3  . MET A 1 337 ? -13.391 -1.336  50.487 1   35.134  ? 326 MET A HG3  1 
ATOM   4854 H  HE1  . MET A 1 337 ? -14.158 0.426   47.449 1   36.144  ? 326 MET A HE1  1 
ATOM   4855 H  HE2  . MET A 1 337 ? -13.486 -0.845  48.13  1   36.112  ? 326 MET A HE2  1 
ATOM   4856 H  HE3  . MET A 1 337 ? -14.981 -0.929  47.581 1   36.117  ? 326 MET A HE3  1 
ATOM   4857 N  N    . GLU A 1 338 ? -17.108 -4.849  49.392 1   31.961  ? 327 GLU A N    1 
ATOM   4858 C  CA   . GLU A 1 338 ? -17.558 -6.02   48.646 1   34.086  ? 327 GLU A CA   1 
ATOM   4859 C  C    . GLU A 1 338 ? -18.919 -5.75   48.005 1   40.591  ? 327 GLU A C    1 
ATOM   4860 O  O    . GLU A 1 338 ? -19.123 -6.031  46.82  1   38.077  ? 327 GLU A O    1 
ATOM   4861 C  CB   . GLU A 1 338 ? -17.746 -7.259  49.514 1   30.821  ? 327 GLU A CB   1 
ATOM   4862 C  CG   . GLU A 1 338 ? -16.422 -7.886  49.956 1   33.552  ? 327 GLU A CG   1 
ATOM   4863 C  CD   . GLU A 1 338 ? -16.584 -9.108  50.868 1   42.084  ? 327 GLU A CD   1 
ATOM   4864 O  OE1  . GLU A 1 338 ? -17.355 -8.972  51.859 1   40.952  ? 327 GLU A OE1  1 
ATOM   4865 O  OE2  . GLU A 1 338 ? -15.89  -10.145 50.716 1   48.099  ? 327 GLU A OE2  1 
ATOM   4866 H  H    . GLU A 1 338 ? -17.019 -4.915  50.299 1   32.632  ? 327 GLU A H    1 
ATOM   4867 H  HA   . GLU A 1 338 ? -16.898 -6.215  47.933 1   34.195  ? 327 GLU A HA   1 
ATOM   4868 H  HB2  . GLU A 1 338 ? -18.267 -7.013  50.307 1   32.234  ? 327 GLU A HB2  1 
ATOM   4869 H  HB3  . GLU A 1 338 ? -18.26  -7.925  49.012 1   32.236  ? 327 GLU A HB3  1 
ATOM   4870 H  HG2  . GLU A 1 338 ? -15.915 -8.155  49.162 1   34.73   ? 327 GLU A HG2  1 
ATOM   4871 H  HG3  . GLU A 1 338 ? -15.89  -7.212  50.429 1   34.662  ? 327 GLU A HG3  1 
ATOM   4872 N  N    . ALA A 1 339 ? -19.844 -5.155  48.766 1   37.994  ? 328 ALA A N    1 
ATOM   4873 C  CA   . ALA A 1 339 ? -21.16  -4.922  48.184 1   40.056  ? 328 ALA A CA   1 
ATOM   4874 C  C    . ALA A 1 339 ? -21.076 -3.857  47.091 1   43.109  ? 328 ALA A C    1 
ATOM   4875 O  O    . ALA A 1 339 ? -21.785 -3.953  46.093 1   39.854  ? 328 ALA A O    1 
ATOM   4876 C  CB   . ALA A 1 339 ? -22.171 -4.522  49.223 1   37.599  ? 328 ALA A CB   1 
ATOM   4877 H  H    . ALA A 1 339 ? -19.669 -4.902  49.626 1   38.961  ? 328 ALA A H    1 
ATOM   4878 H  HA   . ALA A 1 339 ? -21.463 -5.772  47.76  1   39.71   ? 328 ALA A HA   1 
ATOM   4879 H  HB1  . ALA A 1 339 ? -22.251 -5.224  49.89  1   38.315  ? 328 ALA A HB1  1 
ATOM   4880 H  HB2  . ALA A 1 339 ? -21.888 -3.699  49.656 1   38.315  ? 328 ALA A HB2  1 
ATOM   4881 H  HB3  . ALA A 1 339 ? -23.036 -4.381  48.8   1   38.315  ? 328 ALA A HB3  1 
ATOM   4882 N  N    . LEU A 1 340 ? -20.214 -2.84   47.288 1   38.104  ? 329 LEU A N    1 
ATOM   4883 C  CA   . LEU A 1 340 ? -20.134 -1.719  46.366 1   36.515  ? 329 LEU A CA   1 
ATOM   4884 C  C    . LEU A 1 340 ? -19.449 -2.162  45.055 1   39.677  ? 329 LEU A C    1 
ATOM   4885 O  O    . LEU A 1 340 ? -19.798 -1.69   43.979 1   39.673  ? 329 LEU A O    1 
ATOM   4886 C  CB   . LEU A 1 340 ? -19.38  -0.634  47.119 1   34.187  ? 329 LEU A CB   1 
ATOM   4887 C  CG   . LEU A 1 340 ? -19.246 0.731   46.468 1   40.043  ? 329 LEU A CG   1 
ATOM   4888 C  CD1  . LEU A 1 340 ? -20.631 1.374   46.458 1   39.798  ? 329 LEU A CD1  1 
ATOM   4889 C  CD2  . LEU A 1 340 ? -18.266 1.6     47.23  1   39.512  ? 329 LEU A CD2  1 
ATOM   4890 H  H    . LEU A 1 340 ? -19.665 -2.85   48.018 1   38.788  ? 329 LEU A H    1 
ATOM   4891 H  HA   . LEU A 1 340 ? -21.053 -1.407  46.166 1   37.001  ? 329 LEU A HA   1 
ATOM   4892 H  HB2  . LEU A 1 340 ? -19.816 -0.514  47.994 1   36.08   ? 329 LEU A HB2  1 
ATOM   4893 H  HB3  . LEU A 1 340 ? -18.473 -0.972  47.305 1   36.042  ? 329 LEU A HB3  1 
ATOM   4894 H  HG   . LEU A 1 340 ? -18.929 0.617   45.535 1   38.749  ? 329 LEU A HG   1 
ATOM   4895 H  HD11 . LEU A 1 340 ? -21.205 0.9     45.833 1   39.819  ? 329 LEU A HD11 1 
ATOM   4896 H  HD12 . LEU A 1 340 ? -20.555 2.304   46.185 1   39.848  ? 329 LEU A HD12 1 
ATOM   4897 H  HD13 . LEU A 1 340 ? -21.018 1.33    47.348 1   39.807  ? 329 LEU A HD13 1 
ATOM   4898 H  HD21 . LEU A 1 340 ? -17.393 1.173   47.24  1   39.668  ? 329 LEU A HD21 1 
ATOM   4899 H  HD22 . LEU A 1 340 ? -18.578 1.718   48.143 1   39.668  ? 329 LEU A HD22 1 
ATOM   4900 H  HD23 . LEU A 1 340 ? -18.196 2.468   46.797 1   39.668  ? 329 LEU A HD23 1 
ATOM   4901 N  N    . SER A 1 341 ? -18.493 -3.1    45.135 1   40.472  ? 330 SER A N    1 
ATOM   4902 C  CA   . SER A 1 341 ? -17.781 -3.571  43.964 1   40.48   ? 330 SER A CA   1 
ATOM   4903 C  C    . SER A 1 341 ? -18.498 -4.727  43.278 1   42.033  ? 330 SER A C    1 
ATOM   4904 O  O    . SER A 1 341 ? -18.161 -5.064  42.166 1   44.629  ? 330 SER A O    1 
ATOM   4905 C  CB   . SER A 1 341 ? -16.374 -3.986  44.321 1   37.552  ? 330 SER A CB   1 
ATOM   4906 O  OG   . SER A 1 341 ? -16.346 -5.032  45.279 1   40.933  ? 330 SER A OG   1 
ATOM   4907 H  H    . SER A 1 341 ? -18.276 -3.45   45.95  1   40.246  ? 330 SER A H    1 
ATOM   4908 H  HA   . SER A 1 341 ? -17.725 -2.825  43.319 1   40.189  ? 330 SER A HA   1 
ATOM   4909 H  HB2  . SER A 1 341 ? -15.913 -4.28   43.512 1   39.004  ? 330 SER A HB2  1 
ATOM   4910 H  HB3  . SER A 1 341 ? -15.893 -3.214  44.675 1   38.991  ? 330 SER A HB3  1 
ATOM   4911 H  HG   . SER A 1 341 ? -15.529 -5.228  45.431 0   40.94   ? 330 SER A HG   1 
ATOM   4912 N  N    . GLY A 1 342 ? -19.376 -5.403  44.013 1   44.602  ? 331 GLY A N    1 
ATOM   4913 C  CA   . GLY A 1 342 ? -20.014 -6.627  43.574 1   42.271  ? 331 GLY A CA   1 
ATOM   4914 C  C    . GLY A 1 342 ? -19.078 -7.828  43.601 1   47.359  ? 331 GLY A C    1 
ATOM   4915 O  O    . GLY A 1 342 ? -19.372 -8.79   42.937 1   43.824  ? 331 GLY A O    1 
ATOM   4916 H  H    . GLY A 1 342 ? -19.591 -5.082  44.841 1   43.353  ? 331 GLY A H    1 
ATOM   4917 H  HA2  . GLY A 1 342 ? -20.789 -6.807  44.155 1   43.917  ? 331 GLY A HA2  1 
ATOM   4918 H  HA3  . GLY A 1 342 ? -20.352 -6.499  42.656 1   43.912  ? 331 GLY A HA3  1 
ATOM   4919 N  N    . ILE A 1 343 ? -17.984 -7.779  44.384 1   46.514  ? 332 ILE A N    1 
ATOM   4920 C  CA   . ILE A 1 343 ? -17.025 -8.859  44.481 1   41.723  ? 332 ILE A CA   1 
ATOM   4921 C  C    . ILE A 1 343 ? -17.063 -9.399  45.889 1   43.123  ? 332 ILE A C    1 
ATOM   4922 O  O    . ILE A 1 343 ? -16.833 -8.644  46.81  1   49.949  ? 332 ILE A O    1 
ATOM   4923 C  CB   . ILE A 1 343 ? -15.628 -8.348  44.109 1   42.978  ? 332 ILE A CB   1 
ATOM   4924 C  CG1  . ILE A 1 343 ? -15.629 -7.837  42.698 1   49.239  ? 332 ILE A CG1  1 
ATOM   4925 C  CG2  . ILE A 1 343 ? -14.546 -9.43   44.286 1   47.303  ? 332 ILE A CG2  1 
ATOM   4926 C  CD1  . ILE A 1 343 ? -14.421 -6.981  42.364 1   56.752  ? 332 ILE A CD1  1 
ATOM   4927 H  H    . ILE A 1 343 ? -17.84  -7.03   44.888 1   45.522  ? 332 ILE A H    1 
ATOM   4928 H  HA   . ILE A 1 343 ? -17.277 -9.567  43.859 1   43.157  ? 332 ILE A HA   1 
ATOM   4929 H  HB   . ILE A 1 343 ? -15.412 -7.6    44.701 1   44.7    ? 332 ILE A HB   1 
ATOM   4930 H  HG12 . ILE A 1 343 ? -15.654 -8.6    42.086 1   49.265  ? 332 ILE A HG12 1 
ATOM   4931 H  HG13 . ILE A 1 343 ? -16.438 -7.307  42.551 1   49.217  ? 332 ILE A HG13 1 
ATOM   4932 H  HG21 . ILE A 1 343 ? -13.691 -9.093  43.971 1   46.101  ? 332 ILE A HG21 1 
ATOM   4933 H  HG22 . ILE A 1 343 ? -14.789 -10.22  43.774 1   46.02   ? 332 ILE A HG22 1 
ATOM   4934 H  HG23 . ILE A 1 343 ? -14.469 -9.666  45.226 1   46.008  ? 332 ILE A HG23 1 
ATOM   4935 H  HD11 . ILE A 1 343 ? -14.283 -6.32   43.068 1   54.324  ? 332 ILE A HD11 1 
ATOM   4936 H  HD12 . ILE A 1 343 ? -14.573 -6.523  41.516 1   54.378  ? 332 ILE A HD12 1 
ATOM   4937 H  HD13 . ILE A 1 343 ? -13.628 -7.545  42.289 1   54.304  ? 332 ILE A HD13 1 
ATOM   4938 N  N    . ARG A 1 344 ? -17.276 -10.706 46.049 1   45.416  ? 333 ARG A N    1 
ATOM   4939 C  CA   . ARG A 1 344 ? -17.317 -11.325 47.364 1   43.24   ? 333 ARG A CA   1 
ATOM   4940 C  C    . ARG A 1 344 ? -15.999 -12.061 47.582 1   44.311  ? 333 ARG A C    1 
ATOM   4941 O  O    . ARG A 1 344 ? -15.64  -12.928 46.79  1   45.035  ? 333 ARG A O    1 
ATOM   4942 C  CB   . ARG A 1 344 ? -18.575 -12.204 47.443 1   52.409  ? 333 ARG A CB   1 
ATOM   4943 C  CG   . ARG A 1 344 ? -18.8   -12.846 48.811 1   54.857  ? 333 ARG A CG   1 
ATOM   4944 C  CD   . ARG A 1 344 ? -19.356 -11.819 49.836 1   54.675  ? 333 ARG A CD   1 
ATOM   4945 N  NE   . ARG A 1 344 ? -19.535 -12.344 51.208 1   51.364  ? 333 ARG A NE   1 
ATOM   4946 C  CZ   . ARG A 1 344 ? -18.562 -12.669 52.109 1   56.009  ? 333 ARG A CZ   1 
ATOM   4947 N  NH1  . ARG A 1 344 ? -17.256 -12.526 51.853 1   52.78   ? 333 ARG A NH1  1 
ATOM   4948 N  NH2  . ARG A 1 344 ? -18.882 -13.118 53.319 1   56.294  ? 333 ARG A NH2  1 
ATOM   4949 H  H    . ARG A 1 344 ? -17.4   -11.233 45.313 1   44.336  ? 333 ARG A H    1 
ATOM   4950 H  HA   . ARG A 1 344 ? -17.395 -10.61  48.045 1   45.456  ? 333 ARG A HA   1 
ATOM   4951 H  HB2  . ARG A 1 344 ? -19.357 -11.655 47.22  1   50.696  ? 333 ARG A HB2  1 
ATOM   4952 H  HB3  . ARG A 1 344 ? -18.507 -12.913 46.769 1   50.696  ? 333 ARG A HB3  1 
ATOM   4953 H  HG2  . ARG A 1 344 ? -19.436 -13.588 48.722 1   54.223  ? 333 ARG A HG2  1 
ATOM   4954 H  HG3  . ARG A 1 344 ? -17.952 -13.209 49.147 1   54.114  ? 333 ARG A HG3  1 
ATOM   4955 H  HD2  . ARG A 1 344 ? -18.747 -11.054 49.869 1   53.798  ? 333 ARG A HD2  1 
ATOM   4956 H  HD3  . ARG A 1 344 ? -20.218 -11.493 49.508 1   53.893  ? 333 ARG A HD3  1 
ATOM   4957 H  HE   . ARG A 1 344 ? -20.356 -12.461 51.476 1   53.234  ? 333 ARG A HE   1 
ATOM   4958 H  HH11 . ARG A 1 344 ? -16.981 -11.902 51.292 1   53.694  ? 333 ARG A HH11 1 
ATOM   4959 H  HH12 . ARG A 1 344 ? -16.67  -13.059 52.247 1   53.775  ? 333 ARG A HH12 1 
ATOM   4960 H  HH21 . ARG A 1 344 ? -19.685 -13.462 53.463 1   56.169  ? 333 ARG A HH21 1 
ATOM   4961 H  HH22 . ARG A 1 344 ? -18.292 -13.072 53.976 1   56.153  ? 333 ARG A HH22 1 
ATOM   4962 N  N    . THR A 1 345 ? -15.238 -11.741 48.631 1   41.045  ? 334 THR A N    1 
ATOM   4963 C  CA   . THR A 1 345 ? -13.981 -12.449 48.855 1   40.913  ? 334 THR A CA   1 
ATOM   4964 C  C    . THR A 1 345 ? -14.311 -13.728 49.625 1   38.461  ? 334 THR A C    1 
ATOM   4965 O  O    . THR A 1 345 ? -15.463 -14.002 49.91  1   40.28   ? 334 THR A O    1 
ATOM   4966 C  CB   . THR A 1 345 ? -13.005 -11.573 49.628 1   38.192  ? 334 THR A CB   1 
ATOM   4967 O  OG1  . THR A 1 345 ? -13.517 -11.448 50.971 1   33.546  ? 334 THR A OG1  1 
ATOM   4968 C  CG2  . THR A 1 345 ? -12.85  -10.194 49.011 1   37.951  ? 334 THR A CG2  1 
ATOM   4969 H  H    . THR A 1 345 ? -15.501 -11.09  49.215 1   41.728  ? 334 THR A H    1 
ATOM   4970 H  HA   . THR A 1 345 ? -13.584 -12.684 47.988 1   40.024  ? 334 THR A HA   1 
ATOM   4971 H  HB   . THR A 1 345 ? -12.118 -12.004 49.656 1   37.723  ? 334 THR A HB   1 
ATOM   4972 H  HG1  . THR A 1 345 ? -14.303 -11.088 50.956 0   33.41   ? 334 THR A HG1  1 
ATOM   4973 H  HG21 . THR A 1 345 ? -12.067 -9.757  49.386 1   38.038  ? 334 THR A HG21 1 
ATOM   4974 H  HG22 . THR A 1 345 ? -13.64  -9.661  49.201 1   38.064  ? 334 THR A HG22 1 
ATOM   4975 H  HG23 . THR A 1 345 ? -12.742 -10.279 48.048 1   38.034  ? 334 THR A HG23 1 
ATOM   4976 N  N    . GLU A 1 346 ? -13.289 -14.391 50.137 1   41.065  ? 335 GLU A N    1 
ATOM   4977 C  CA   . GLU A 1 346 ? -13.519 -15.579 50.969 1   46.877  ? 335 GLU A CA   1 
ATOM   4978 C  C    . GLU A 1 346 ? -13.619 -15.239 52.449 1   40.402  ? 335 GLU A C    1 
ATOM   4979 O  O    . GLU A 1 346 ? -13.555 -16.107 53.311 1   34.363  ? 335 GLU A O    1 
ATOM   4980 C  CB   . GLU A 1 346 ? -12.293 -16.494 50.822 1   52.1    ? 335 GLU A CB   1 
ATOM   4981 C  CG   . GLU A 1 346 ? -12.067 -17.031 49.399 1   66.394  ? 335 GLU A CG   1 
ATOM   4982 C  CD   . GLU A 1 346 ? -13.135 -18.064 49.002 1   89.947  ? 335 GLU A CD   1 
ATOM   4983 O  OE1  . GLU A 1 346 ? -13.103 -19.22  49.534 1   93.704  ? 335 GLU A OE1  1 
ATOM   4984 O  OE2  . GLU A 1 346 ? -14.047 -17.699 48.199 1   78.954  ? 335 GLU A OE2  1 
ATOM   4985 H  H    . GLU A 1 346 ? -12.432 -14.126 49.965 1   41.714  ? 335 GLU A H    1 
ATOM   4986 H  HA   . GLU A 1 346 ? -14.342 -16.041 50.67  1   45.392  ? 335 GLU A HA   1 
ATOM   4987 H  HB2  . GLU A 1 346 ? -11.495 -16.001 51.105 1   53.469  ? 335 GLU A HB2  1 
ATOM   4988 H  HB3  . GLU A 1 346 ? -12.397 -17.261 51.423 1   53.494  ? 335 GLU A HB3  1 
ATOM   4989 H  HG2  . GLU A 1 346 ? -12.091 -16.287 48.761 1   67.175  ? 335 GLU A HG2  1 
ATOM   4990 H  HG3  . GLU A 1 346 ? -11.183 -17.451 49.346 1   67.321  ? 335 GLU A HG3  1 
ATOM   4991 N  N    . VAL A 1 347 ? -13.581 -13.965 52.791 1   41.499  ? 336 VAL A N    1 
ATOM   4992 C  CA   . VAL A 1 347 ? -13.528 -13.621 54.205 1   35.791  ? 336 VAL A CA   1 
ATOM   4993 C  C    . VAL A 1 347 ? -14.909 -13.882 54.818 1   34.091  ? 336 VAL A C    1 
ATOM   4994 O  O    . VAL A 1 347 ? -15.952 -13.451 54.332 1   39.642  ? 336 VAL A O    1 
ATOM   4995 C  CB   . VAL A 1 347 ? -13.102 -12.161 54.426 1   34.764  ? 336 VAL A CB   1 
ATOM   4996 C  CG1  . VAL A 1 347 ? -13.209 -11.8   55.89  1   29.276  ? 336 VAL A CG1  1 
ATOM   4997 C  CG2  . VAL A 1 347 ? -11.684 -11.924 53.903 1   38.618  ? 336 VAL A CG2  1 
ATOM   4998 H  H    . VAL A 1 347 ? -13.587 -13.302 52.163 1   39.897  ? 336 VAL A H    1 
ATOM   4999 H  HA   . VAL A 1 347 ? -12.874 -14.201 54.641 1   36.348  ? 336 VAL A HA   1 
ATOM   5000 H  HB   . VAL A 1 347 ? -13.723 -11.59  53.916 1   34.505  ? 336 VAL A HB   1 
ATOM   5001 H  HG11 . VAL A 1 347 ? -12.887 -12.54  56.432 1   30.874  ? 336 VAL A HG11 1 
ATOM   5002 H  HG12 . VAL A 1 347 ? -14.137 -11.616 56.113 1   30.855  ? 336 VAL A HG12 1 
ATOM   5003 H  HG13 . VAL A 1 347 ? -12.672 -11.011 56.071 1   30.909  ? 336 VAL A HG13 1 
ATOM   5004 H  HG21 . VAL A 1 347 ? -11.341 -11.086 54.257 1   37.334  ? 336 VAL A HG21 1 
ATOM   5005 H  HG22 . VAL A 1 347 ? -11.699 -11.882 52.932 1   37.397  ? 336 VAL A HG22 1 
ATOM   5006 H  HG23 . VAL A 1 347 ? -11.108 -12.652 54.183 1   37.409  ? 336 VAL A HG23 1 
ATOM   5007 N  N    . GLN A 1 348 ? -14.87  -14.452 55.994 1   36.803  ? 337 GLN A N    1 
ATOM   5008 C  CA   . GLN A 1 348 ? -16.053 -14.66  56.79  1   44.582  ? 337 GLN A CA   1 
ATOM   5009 C  C    . GLN A 1 348 ? -15.812 -13.952 58.116 1   40.311  ? 337 GLN A C    1 
ATOM   5010 O  O    . GLN A 1 348 ? -14.775 -14.13  58.744 1   44.114  ? 337 GLN A O    1 
ATOM   5011 C  CB   . GLN A 1 348 ? -16.297 -16.176 56.902 1   60.399  ? 337 GLN A CB   1 
ATOM   5012 C  CG   . GLN A 1 348 ? -17.022 -16.744 55.677 1   72.311  ? 337 GLN A CG   1 
ATOM   5013 C  CD   . GLN A 1 348 ? -17.839 -17.958 56.056 1   102.191 ? 337 GLN A CD   1 
ATOM   5014 O  OE1  . GLN A 1 348 ? -19.065 -17.911 56.21  1   104.234 ? 337 GLN A OE1  1 
ATOM   5015 N  NE2  . GLN A 1 348 ? -17.141 -19.053 56.31  1   94.211  ? 337 GLN A NE2  1 
ATOM   5016 H  H    . GLN A 1 348 ? -14.066 -14.731 56.328 1   37.748  ? 337 GLN A H    1 
ATOM   5017 H  HA   . GLN A 1 348 ? -16.824 -14.238 56.334 1   44.634  ? 337 GLN A HA   1 
ATOM   5018 H  HB2  . GLN A 1 348 ? -15.435 -16.632 57.006 1   58.568  ? 337 GLN A HB2  1 
ATOM   5019 H  HB3  . GLN A 1 348 ? -16.83  -16.354 57.705 1   58.766  ? 337 GLN A HB3  1 
ATOM   5020 H  HG2  . GLN A 1 348 ? -17.615 -16.061 55.297 1   74.725  ? 337 GLN A HG2  1 
ATOM   5021 H  HG3  . GLN A 1 348 ? -16.366 -16.994 54.992 1   75.135  ? 337 GLN A HG3  1 
ATOM   5022 H  HE21 . GLN A 1 348 ? -17.557 -19.831 56.4   1   96.546  ? 337 GLN A HE21 1 
ATOM   5023 H  HE22 . GLN A 1 348 ? -16.258 -19.01  56.389 1   96.151  ? 337 GLN A HE22 1 
ATOM   5024 N  N    . ASP A 1 349 ? -16.782 -13.11  58.463 1   38.418  ? 338 ASP A N    1 
ATOM   5025 C  CA   . ASP A 1 349 ? -16.754 -12.256 59.625 1   37.292  ? 338 ASP A CA   1 
ATOM   5026 C  C    . ASP A 1 349 ? -16.782 -13.207 60.808 1   38.503  ? 338 ASP A C    1 
ATOM   5027 O  O    . ASP A 1 349 ? -17.782 -13.849 60.983 1   37.803  ? 338 ASP A O    1 
ATOM   5028 C  CB   . ASP A 1 349 ? -17.909 -11.249 59.506 1   32.648  ? 338 ASP A CB   1 
ATOM   5029 C  CG   . ASP A 1 349 ? -18.281 -10.5   60.785 1   36.505  ? 338 ASP A CG   1 
ATOM   5030 O  OD1  . ASP A 1 349 ? -17.539 -10.723 61.768 1   36.168  ? 338 ASP A OD1  1 
ATOM   5031 O  OD2  . ASP A 1 349 ? -19.291 -9.695  60.8   1   40.484  ? 338 ASP A OD2  1 
ATOM   5032 H  H    . ASP A 1 349 ? -17.522 -13.073 57.928 1   38.605  ? 338 ASP A H    1 
ATOM   5033 H  HA   . ASP A 1 349 ? -15.905 -11.761 59.626 1   36.836  ? 338 ASP A HA   1 
ATOM   5034 H  HB2  . ASP A 1 349 ? -17.674 -10.585 58.825 1   34.528  ? 338 ASP A HB2  1 
ATOM   5035 H  HB3  . ASP A 1 349 ? -18.711 -11.722 59.199 1   34.57   ? 338 ASP A HB3  1 
ATOM   5036 N  N    . PRO A 1 350 ? -15.756 -13.318 61.673 1   36.162  ? 339 PRO A N    1 
ATOM   5037 C  CA   . PRO A 1 350 ? -15.821 -14.286 62.768 1   34.784  ? 339 PRO A CA   1 
ATOM   5038 C  C    . PRO A 1 350 ? -16.798 -13.928 63.892 1   35.07   ? 339 PRO A C    1 
ATOM   5039 O  O    . PRO A 1 350 ? -16.901 -14.715 64.84  1   35.447  ? 339 PRO A O    1 
ATOM   5040 C  CB   . PRO A 1 350 ? -14.363 -14.314 63.336 1   36.581  ? 339 PRO A CB   1 
ATOM   5041 C  CG   . PRO A 1 350 ? -13.933 -12.848 63.082 1   34.225  ? 339 PRO A CG   1 
ATOM   5042 C  CD   . PRO A 1 350 ? -14.557 -12.455 61.742 1   38.472  ? 339 PRO A CD   1 
ATOM   5043 H  HA   . PRO A 1 350 ? -16.048 -15.176 62.398 1   35.444  ? 339 PRO A HA   1 
ATOM   5044 H  HB2  . PRO A 1 350 ? -14.352 -14.533 64.297 1   35.646  ? 339 PRO A HB2  1 
ATOM   5045 H  HB3  . PRO A 1 350 ? -13.796 -14.948 62.837 1   35.649  ? 339 PRO A HB3  1 
ATOM   5046 H  HG2  . PRO A 1 350 ? -14.259 -12.264 63.798 1   35.664  ? 339 PRO A HG2  1 
ATOM   5047 H  HG3  . PRO A 1 350 ? -12.957 -12.777 63.041 1   35.664  ? 339 PRO A HG3  1 
ATOM   5048 H  HD2  . PRO A 1 350 ? -14.803 -11.504 61.732 1   36.953  ? 339 PRO A HD2  1 
ATOM   5049 H  HD3  . PRO A 1 350 ? -13.943 -12.64  60.998 1   36.954  ? 339 PRO A HD3  1 
ATOM   5050 N  N    . LEU A 1 351 ? -17.411 -12.714 63.861 1   34.727  ? 340 LEU A N    1 
ATOM   5051 C  CA   . LEU A 1 351 ? -18.374 -12.313 64.896 1   34.672  ? 340 LEU A CA   1 
ATOM   5052 C  C    . LEU A 1 351 ? -19.82  -12.362 64.411 1   34.71   ? 340 LEU A C    1 
ATOM   5053 O  O    . LEU A 1 351 ? -20.707 -12.008 65.175 1   31.099  ? 340 LEU A O    1 
ATOM   5054 C  CB   . LEU A 1 351 ? -18.147 -10.932 65.518 1   34.516  ? 340 LEU A CB   1 
ATOM   5055 C  CG   . LEU A 1 351 ? -17.033 -10.796 66.541 1   40.505  ? 340 LEU A CG   1 
ATOM   5056 C  CD1  . LEU A 1 351 ? -16.837 -9.353  66.985 1   42.873  ? 340 LEU A CD1  1 
ATOM   5057 C  CD2  . LEU A 1 351 ? -17.371 -11.618 67.678 1   42.17   ? 340 LEU A CD2  1 
ATOM   5058 H  H    . LEU A 1 351 ? -17.214 -12.122 63.194 1   34.824  ? 340 LEU A H    1 
ATOM   5059 H  HA   . LEU A 1 351 ? -18.307 -12.983 65.621 1   34.749  ? 340 LEU A HA   1 
ATOM   5060 H  HB2  . LEU A 1 351 ? -17.968 -10.298 64.786 1   35.852  ? 340 LEU A HB2  1 
ATOM   5061 H  HB3  . LEU A 1 351 ? -18.987 -10.64  65.941 1   35.876  ? 340 LEU A HB3  1 
ATOM   5062 H  HG   . LEU A 1 351 ? -16.192 -11.129 66.139 1   40.051  ? 340 LEU A HG   1 
ATOM   5063 H  HD11 . LEU A 1 351 ? -16.623 -8.803  66.215 1   42.112  ? 340 LEU A HD11 1 
ATOM   5064 H  HD12 . LEU A 1 351 ? -16.109 -9.306  67.628 1   42.146  ? 340 LEU A HD12 1 
ATOM   5065 H  HD13 . LEU A 1 351 ? -17.654 -9.027  67.399 1   42.149  ? 340 LEU A HD13 1 
ATOM   5066 H  HD21 . LEU A 1 351 ? -17.232 -12.554 67.458 1   41.533  ? 340 LEU A HD21 1 
ATOM   5067 H  HD22 . LEU A 1 351 ? -18.302 -11.477 67.919 1   41.536  ? 340 LEU A HD22 1 
ATOM   5068 H  HD23 . LEU A 1 351 ? -16.805 -11.379 68.431 1   41.617  ? 340 LEU A HD23 1 
ATOM   5069 N  N    . LEU A 1 352 ? -20.039 -12.597 63.121 1   32.723  ? 341 LEU A N    1 
ATOM   5070 C  CA   . LEU A 1 352 ? -21.353 -12.372 62.535 1   37.527  ? 341 LEU A CA   1 
ATOM   5071 C  C    . LEU A 1 352 ? -22.412 -13.178 63.263 1   39.332  ? 341 LEU A C    1 
ATOM   5072 O  O    . LEU A 1 352 ? -23.435 -12.645 63.681 1   39.747  ? 341 LEU A O    1 
ATOM   5073 C  CB   . LEU A 1 352 ? -21.296 -12.694 61.044 1   36.385  ? 341 LEU A CB   1 
ATOM   5074 C  CG   . LEU A 1 352 ? -22.631 -12.774 60.312 1   46.402  ? 341 LEU A CG   1 
ATOM   5075 C  CD1  . LEU A 1 352 ? -23.265 -11.399 60.331 1   41.939  ? 341 LEU A CD1  1 
ATOM   5076 C  CD2  . LEU A 1 352 ? -22.422 -13.294 58.885 1   45.814  ? 341 LEU A CD2  1 
ATOM   5077 H  H    . LEU A 1 352 ? -19.363 -12.907 62.591 1   34.283  ? 341 LEU A H    1 
ATOM   5078 H  HA   . LEU A 1 352 ? -21.572 -11.411 62.644 1   36.689  ? 341 LEU A HA   1 
ATOM   5079 H  HB2  . LEU A 1 352 ? -20.742 -12.008 60.604 1   38.75   ? 341 LEU A HB2  1 
ATOM   5080 H  HB3  . LEU A 1 352 ? -20.833 -13.557 60.936 1   38.711  ? 341 LEU A HB3  1 
ATOM   5081 H  HG   . LEU A 1 352 ? -23.224 -13.406 60.794 1   43.406  ? 341 LEU A HG   1 
ATOM   5082 H  HD11 . LEU A 1 352 ? -23.532 -11.176 61.238 1   43.166  ? 341 LEU A HD11 1 
ATOM   5083 H  HD12 . LEU A 1 352 ? -24.048 -11.395 59.755 1   43.19   ? 341 LEU A HD12 1 
ATOM   5084 H  HD13 . LEU A 1 352 ? -22.626 -10.741 60.011 1   43.131  ? 341 LEU A HD13 1 
ATOM   5085 H  HD21 . LEU A 1 352 ? -22.028 -14.182 58.917 1   45.985  ? 341 LEU A HD21 1 
ATOM   5086 H  HD22 . LEU A 1 352 ? -21.828 -12.694 58.404 1   45.985  ? 341 LEU A HD22 1 
ATOM   5087 H  HD23 . LEU A 1 352 ? -23.278 -13.338 58.426 1   45.985  ? 341 LEU A HD23 1 
ATOM   5088 N  N    . GLU A 1 353 ? -22.132 -14.455 63.475 1   38.23   ? 342 GLU A N    1 
ATOM   5089 C  CA   . GLU A 1 353 ? -23.16  -15.281 64.034 1   43.112  ? 342 GLU A CA   1 
ATOM   5090 C  C    . GLU A 1 353 ? -23.421 -14.887 65.489 1   42.173  ? 342 GLU A C    1 
ATOM   5091 O  O    . GLU A 1 353 ? -24.564 -14.901 65.94  1   37.879  ? 342 GLU A O    1 
ATOM   5092 C  CB   . GLU A 1 353 ? -22.701 -16.729 63.862 1   48.791  ? 342 GLU A CB   1 
ATOM   5093 C  CG   . GLU A 1 353 ? -23.852 -17.662 64.197 1   68.058  ? 342 GLU A CG   1 
ATOM   5094 C  CD   . GLU A 1 353 ? -23.419 -19.091 64.436 1   91.88   ? 342 GLU A CD   1 
ATOM   5095 O  OE1  . GLU A 1 353 ? -22.458 -19.51  63.746 1   86.409  ? 342 GLU A OE1  1 
ATOM   5096 O  OE2  . GLU A 1 353 ? -24.049 -19.754 65.296 1   90.368  ? 342 GLU A OE2  1 
ATOM   5097 H  H    . GLU A 1 353 ? -21.313 -14.807 63.273 1   39.625  ? 342 GLU A H    1 
ATOM   5098 H  HA   . GLU A 1 353 ? -23.991 -15.147 63.513 1   42.847  ? 342 GLU A HA   1 
ATOM   5099 H  HB2  . GLU A 1 353 ? -22.407 -16.869 62.938 1   51.039  ? 342 GLU A HB2  1 
ATOM   5100 H  HB3  . GLU A 1 353 ? -21.939 -16.9   64.454 1   51.311  ? 342 GLU A HB3  1 
ATOM   5101 H  HG2  . GLU A 1 353 ? -24.311 -17.338 65     1   67.18   ? 342 GLU A HG2  1 
ATOM   5102 H  HG3  . GLU A 1 353 ? -24.499 -17.651 63.459 1   67.515  ? 342 GLU A HG3  1 
ATOM   5103 N  N    . PHE A 1 354 ? -22.343 -14.637 66.239 1   33.173  ? 343 PHE A N    1 
ATOM   5104 C  CA   . PHE A 1 354 ? -22.447 -14.125 67.592 1   31.894  ? 343 PHE A CA   1 
ATOM   5105 C  C    . PHE A 1 354 ? -23.31  -12.858 67.673 1   34.04   ? 343 PHE A C    1 
ATOM   5106 O  O    . PHE A 1 354 ? -24.261 -12.784 68.449 1   32.499  ? 343 PHE A O    1 
ATOM   5107 C  CB   . PHE A 1 354 ? -21.033 -13.911 68.098 1   34.188  ? 343 PHE A CB   1 
ATOM   5108 C  CG   . PHE A 1 354 ? -21.018 -13.382 69.525 1   36.013  ? 343 PHE A CG   1 
ATOM   5109 C  CD1  . PHE A 1 354 ? -21.017 -12.02  69.803 1   36.762  ? 343 PHE A CD1  1 
ATOM   5110 C  CD2  . PHE A 1 354 ? -21.007 -14.253 70.587 1   33.815  ? 343 PHE A CD2  1 
ATOM   5111 C  CE1  . PHE A 1 354 ? -20.999 -11.551 71.111 1   33.039  ? 343 PHE A CE1  1 
ATOM   5112 C  CE2  . PHE A 1 354 ? -21.046 -13.779 71.895 1   37.364  ? 343 PHE A CE2  1 
ATOM   5113 C  CZ   . PHE A 1 354 ? -21.014 -12.433 72.159 1   31.973  ? 343 PHE A CZ   1 
ATOM   5114 H  H    . PHE A 1 354 ? -21.512 -14.8   65.894 1   34.882  ? 343 PHE A H    1 
ATOM   5115 H  HA   . PHE A 1 354 ? -22.873 -14.826 68.153 1   32.941  ? 343 PHE A HA   1 
ATOM   5116 H  HB2  . PHE A 1 354 ? -20.55  -14.766 68.064 1   34.05   ? 343 PHE A HB2  1 
ATOM   5117 H  HB3  . PHE A 1 354 ? -20.578 -13.269 67.509 1   34.033  ? 343 PHE A HB3  1 
ATOM   5118 H  HD1  . PHE A 1 354 ? -21.005 -11.403 69.089 1   35.639  ? 343 PHE A HD1  1 
ATOM   5119 H  HD2  . PHE A 1 354 ? -21.037 -15.183 70.425 1   35.092  ? 343 PHE A HD2  1 
ATOM   5120 H  HE1  . PHE A 1 354 ? -20.999 -10.622 71.277 1   33.65   ? 343 PHE A HE1  1 
ATOM   5121 H  HE2  . PHE A 1 354 ? -21.031 -14.394 72.611 1   35.18   ? 343 PHE A HE2  1 
ATOM   5122 H  HZ   . PHE A 1 354 ? -21.013 -12.119 73.049 1   33.457  ? 343 PHE A HZ   1 
ATOM   5123 N  N    . ILE A 1 355 ? -23.094 -11.879 66.794 1   31.116  ? 344 ILE A N    1 
ATOM   5124 C  CA   . ILE A 1 355 ? -23.877 -10.649 66.898 1   33.863  ? 344 ILE A CA   1 
ATOM   5125 C  C    . ILE A 1 355 ? -25.336 -10.866 66.455 1   33.532  ? 344 ILE A C    1 
ATOM   5126 O  O    . ILE A 1 355 ? -26.241 -10.191 66.948 1   33.526  ? 344 ILE A O    1 
ATOM   5127 C  CB   . ILE A 1 355 ? -23.198 -9.524  66.109 1   27.463  ? 344 ILE A CB   1 
ATOM   5128 C  CG1  . ILE A 1 355 ? -21.855 -9.144  66.756 1   32.685  ? 344 ILE A CG1  1 
ATOM   5129 C  CG2  . ILE A 1 355 ? -24.073 -8.29   65.997 1   28.826  ? 344 ILE A CG2  1 
ATOM   5130 C  CD1  . ILE A 1 355 ? -20.989 -8.328  65.828 1   30.072  ? 344 ILE A CD1  1 
ATOM   5131 H  H    . ILE A 1 355 ? -22.466 -11.966 66.135 1   32.344  ? 344 ILE A H    1 
ATOM   5132 H  HA   . ILE A 1 355 ? -23.888 -10.382 67.838 1   31.998  ? 344 ILE A HA   1 
ATOM   5133 H  HB   . ILE A 1 355 ? -23.017 -9.853  65.206 1   29.777  ? 344 ILE A HB   1 
ATOM   5134 H  HG12 . ILE A 1 355 ? -22.027 -8.629  67.571 1   30.836  ? 344 ILE A HG12 1 
ATOM   5135 H  HG13 . ILE A 1 355 ? -21.376 -9.96   67.006 1   30.851  ? 344 ILE A HG13 1 
ATOM   5136 H  HG21 . ILE A 1 355 ? -23.547 -7.542  65.671 1   28.499  ? 344 ILE A HG21 1 
ATOM   5137 H  HG22 . ILE A 1 355 ? -24.436 -8.07   66.871 1   28.45   ? 344 ILE A HG22 1 
ATOM   5138 H  HG23 . ILE A 1 355 ? -24.802 -8.461  65.381 1   28.51   ? 344 ILE A HG23 1 
ATOM   5139 H  HD11 . ILE A 1 355 ? -20.986 -8.734  64.941 1   30.809  ? 344 ILE A HD11 1 
ATOM   5140 H  HD12 . ILE A 1 355 ? -20.077 -8.304  66.175 1   30.816  ? 344 ILE A HD12 1 
ATOM   5141 H  HD13 . ILE A 1 355 ? -21.334 -7.417  65.765 1   30.789  ? 344 ILE A HD13 1 
ATOM   5142 N  N    . GLN A 1 356 ? -25.566 -11.771 65.504 1   33.149  ? 345 GLN A N    1 
ATOM   5143 C  CA   . GLN A 1 356 ? -26.922 -12.133 65.085 1   39.073  ? 345 GLN A CA   1 
ATOM   5144 C  C    . GLN A 1 356 ? -27.739 -12.682 66.247 1   38.148  ? 345 GLN A C    1 
ATOM   5145 O  O    . GLN A 1 356 ? -28.883 -12.325 66.395 1   39.34   ? 345 GLN A O    1 
ATOM   5146 C  CB   . GLN A 1 356 ? -26.913 -13.205 64.007 1   39.14   ? 345 GLN A CB   1 
ATOM   5147 C  CG   . GLN A 1 356 ? -26.713 -12.57  62.642 1   46.327  ? 345 GLN A CG   1 
ATOM   5148 C  CD   . GLN A 1 356 ? -26.342 -13.578 61.57  1   46.287  ? 345 GLN A CD   1 
ATOM   5149 O  OE1  . GLN A 1 356 ? -25.903 -14.71  61.79  1   40.117  ? 345 GLN A OE1  1 
ATOM   5150 N  NE2  . GLN A 1 356 ? -26.559 -13.138 60.352 1   51.75   ? 345 GLN A NE2  1 
ATOM   5151 H  H    . GLN A 1 356 ? -24.857 -12.175 65.092 1   34.534  ? 345 GLN A H    1 
ATOM   5152 H  HA   . GLN A 1 356 ? -27.369 -11.321 64.735 1   37.712  ? 345 GLN A HA   1 
ATOM   5153 H  HB2  . GLN A 1 356 ? -26.19  -13.842 64.183 1   40.618  ? 345 GLN A HB2  1 
ATOM   5154 H  HB3  . GLN A 1 356 ? -27.763 -13.693 64.019 1   40.636  ? 345 GLN A HB3  1 
ATOM   5155 H  HG2  . GLN A 1 356 ? -27.539 -12.112 62.374 1   44.578  ? 345 GLN A HG2  1 
ATOM   5156 H  HG3  . GLN A 1 356 ? -26.004 -11.895 62.7   1   44.542  ? 345 GLN A HG3  1 
ATOM   5157 H  HE21 . GLN A 1 356 ? -26.895 -13.684 59.738 1   49.995  ? 345 GLN A HE21 1 
ATOM   5158 H  HE22 . GLN A 1 356 ? -26.37  -12.296 60.144 1   49.975  ? 345 GLN A HE22 1 
ATOM   5159 N  N    . GLN A 1 357 ? -27.103 -13.505 67.074 1   35.472  ? 346 GLN A N    1 
ATOM   5160 C  CA   . GLN A 1 357 ? -27.724 -14     68.283 1   37.413  ? 346 GLN A CA   1 
ATOM   5161 C  C    . GLN A 1 357 ? -28.005 -12.959 69.357 1   36.539  ? 346 GLN A C    1 
ATOM   5162 O  O    . GLN A 1 357 ? -28.877 -13.161 70.179 1   40.244  ? 346 GLN A O    1 
ATOM   5163 C  CB   . GLN A 1 357 ? -26.861 -15.122 68.833 1   41.955  ? 346 GLN A CB   1 
ATOM   5164 C  CG   . GLN A 1 357 ? -26.866 -16.42  68.034 1   48.301  ? 346 GLN A CG   1 
ATOM   5165 C  CD   . GLN A 1 357 ? -26.005 -17.444 68.759 1   59.357  ? 346 GLN A CD   1 
ATOM   5166 O  OE1  . GLN A 1 357 ? -24.797 -17.529 68.543 1   62.825  ? 346 GLN A OE1  1 
ATOM   5167 N  NE2  . GLN A 1 357 ? -26.575 -18.099 69.764 1   70.103  ? 346 GLN A NE2  1 
ATOM   5168 H  H    . GLN A 1 357 ? -26.253 -13.775 66.873 1   36.6    ? 346 GLN A H    1 
ATOM   5169 H  HA   . GLN A 1 357 ? -28.592 -14.404 68.026 1   37.675  ? 346 GLN A HA   1 
ATOM   5170 H  HB2  . GLN A 1 357 ? -25.939 -14.798 68.896 1   42.107  ? 346 GLN A HB2  1 
ATOM   5171 H  HB3  . GLN A 1 357 ? -27.162 -15.318 69.745 1   42.223  ? 346 GLN A HB3  1 
ATOM   5172 H  HG2  . GLN A 1 357 ? -27.783 -16.757 67.948 1   49.116  ? 346 GLN A HG2  1 
ATOM   5173 H  HG3  . GLN A 1 357 ? -26.509 -16.261 67.134 1   48.984  ? 346 GLN A HG3  1 
ATOM   5174 H  HE21 . GLN A 1 357 ? -26.13  -18.745 70.18  1   66.497  ? 346 GLN A HE21 1 
ATOM   5175 H  HE22 . GLN A 1 357 ? -27.399 -17.892 70.019 1   66.28   ? 346 GLN A HE22 1 
ATOM   5176 N  N    . GLN A 1 358 ? -27.338 -11.825 69.331 1   37.062  ? 347 GLN A N    1 
ATOM   5177 C  CA   . GLN A 1 358 ? -27.512 -10.821 70.355 1   35.047  ? 347 GLN A CA   1 
ATOM   5178 C  C    . GLN A 1 358 ? -28.651 -9.857  70     1   30.498  ? 347 GLN A C    1 
ATOM   5179 O  O    . GLN A 1 358 ? -28.937 -8.942  70.754 1   30.055  ? 347 GLN A O    1 
ATOM   5180 C  CB   . GLN A 1 358 ? -26.23  -9.949  70.449 1   34.117  ? 347 GLN A CB   1 
ATOM   5181 C  CG   . GLN A 1 358 ? -25.045 -10.711 71.02  1   39.3    ? 347 GLN A CG   1 
ATOM   5182 C  CD   . GLN A 1 358 ? -23.845 -9.813  71.204 1   38.08   ? 347 GLN A CD   1 
ATOM   5183 O  OE1  . GLN A 1 358 ? -23.488 -9.072  70.294 1   30.285  ? 347 GLN A OE1  1 
ATOM   5184 N  NE2  . GLN A 1 358 ? -23.43  -9.655  72.449 1   36.677  ? 347 GLN A NE2  1 
ATOM   5185 H  H    . GLN A 1 358 ? -26.741 -11.668 68.659 1   36.438  ? 347 GLN A H    1 
ATOM   5186 H  HA   . GLN A 1 358 ? -27.703 -11.26  71.218 1   34.43   ? 347 GLN A HA   1 
ATOM   5187 H  HB2  . GLN A 1 358 ? -26.001 -9.621  69.554 1   35.41   ? 347 GLN A HB2  1 
ATOM   5188 H  HB3  . GLN A 1 358 ? -26.411 -9.171  71.016 1   35.386  ? 347 GLN A HB3  1 
ATOM   5189 H  HG2  . GLN A 1 358 ? -25.291 -11.099 71.884 1   37.766  ? 347 GLN A HG2  1 
ATOM   5190 H  HG3  . GLN A 1 358 ? -24.807 -11.445 70.417 1   37.746  ? 347 GLN A HG3  1 
ATOM   5191 H  HE21 . GLN A 1 358 ? -23.297 -8.84   72.771 1   37.104  ? 347 GLN A HE21 1 
ATOM   5192 H  HE22 . GLN A 1 358 ? -23.286 -10.365 72.961 1   37.108  ? 347 GLN A HE22 1 
ATOM   5193 N  N    . GLN A 1 359 ? -29.153 -9.926  68.767 1   30.622  ? 348 GLN A N    1 
ATOM   5194 C  CA   . GLN A 1 359 ? -30.071 -8.915  68.283 1   32.233  ? 348 GLN A CA   1 
ATOM   5195 C  C    . GLN A 1 359 ? -31.325 -8.858  69.155 1   28.369  ? 348 GLN A C    1 
ATOM   5196 O  O    . GLN A 1 359 ? -31.7   -9.846  69.805 1   31.956  ? 348 GLN A O    1 
ATOM   5197 C  CB   . GLN A 1 359 ? -30.551 -9.269  66.874 1   34.88   ? 348 GLN A CB   1 
ATOM   5198 C  CG   . GLN A 1 359 ? -29.51  -9.123  65.768 1   32.095  ? 348 GLN A CG   1 
ATOM   5199 C  CD   . GLN A 1 359 ? -28.894 -7.742  65.738 1   31.684  ? 348 GLN A CD   1 
ATOM   5200 O  OE1  . GLN A 1 359 ? -29.515 -6.79   65.306 1   32.18   ? 348 GLN A OE1  1 
ATOM   5201 N  NE2  . GLN A 1 359 ? -27.602 -7.633  66.063 1   37.75   ? 348 GLN A NE2  1 
ATOM   5202 H  H    . GLN A 1 359 ? -28.92  -10.613 68.213 1   31.092  ? 348 GLN A H    1 
ATOM   5203 H  HA   . GLN A 1 359 ? -29.613 -8.041  68.292 1   31.624  ? 348 GLN A HA   1 
ATOM   5204 H  HB2  . GLN A 1 359 ? -30.87  -10.196 66.882 1   33.591  ? 348 GLN A HB2  1 
ATOM   5205 H  HB3  . GLN A 1 359 ? -31.318 -8.698  66.657 1   33.577  ? 348 GLN A HB3  1 
ATOM   5206 H  HG2  . GLN A 1 359 ? -28.8   -9.786  65.9   1   32.72   ? 348 GLN A HG2  1 
ATOM   5207 H  HG3  . GLN A 1 359 ? -29.93  -9.303  64.9   1   32.629  ? 348 GLN A HG3  1 
ATOM   5208 H  HE21 . GLN A 1 359 ? -27.12  -6.963  65.738 1   35.725  ? 348 GLN A HE21 1 
ATOM   5209 H  HE22 . GLN A 1 359 ? -27.229 -8.229  66.603 1   35.707  ? 348 GLN A HE22 1 
ATOM   5210 N  N    . PRO A 1 360 ? -31.893 -7.655  69.353 1   32.83   ? 349 PRO A N    1 
ATOM   5211 C  CA   . PRO A 1 360 ? -33.11  -7.46   70.175 1   43.522  ? 349 PRO A CA   1 
ATOM   5212 C  C    . PRO A 1 360 ? -34.248 -8.371  69.686 1   39.853  ? 349 PRO A C    1 
ATOM   5213 O  O    . PRO A 1 360 ? -34.363 -8.583  68.494 1   39.915  ? 349 PRO A O    1 
ATOM   5214 C  CB   . PRO A 1 360 ? -33.487 -5.971  69.967 1   38.936  ? 349 PRO A CB   1 
ATOM   5215 C  CG   . PRO A 1 360 ? -32.259 -5.327  69.42  1   32.715  ? 349 PRO A CG   1 
ATOM   5216 C  CD   . PRO A 1 360 ? -31.509 -6.427  68.629 1   31.351  ? 349 PRO A CD   1 
ATOM   5217 H  HA   . PRO A 1 360 ? -32.907 -7.633  71.129 1   39.781  ? 349 PRO A HA   1 
ATOM   5218 H  HB2  . PRO A 1 360 ? -34.238 -5.884  69.333 1   38.332  ? 349 PRO A HB2  1 
ATOM   5219 H  HB3  . PRO A 1 360 ? -33.749 -5.554  70.822 1   38.326  ? 349 PRO A HB3  1 
ATOM   5220 H  HG2  . PRO A 1 360 ? -32.495 -4.581  68.83  1   33.745  ? 349 PRO A HG2  1 
ATOM   5221 H  HG3  . PRO A 1 360 ? -31.698 -4.983  70.146 1   33.745  ? 349 PRO A HG3  1 
ATOM   5222 H  HD2  . PRO A 1 360 ? -31.805 -6.457  67.693 1   32.007  ? 349 PRO A HD2  1 
ATOM   5223 H  HD3  . PRO A 1 360 ? -30.538 -6.279  68.661 1   31.988  ? 349 PRO A HD3  1 
ATOM   5224 N  N    . ARG A 1 361 ? -34.98  -8.949  70.627 1   38.581  ? 350 ARG A N    1 
ATOM   5225 C  CA   . ARG A 1 361 ? -36.168 -9.758  70.42  1   42.425  ? 350 ARG A CA   1 
ATOM   5226 C  C    . ARG A 1 361 ? -37.313 -8.914  69.824 1   39.462  ? 350 ARG A C    1 
ATOM   5227 O  O    . ARG A 1 361 ? -37.26  -7.674  69.697 1   40.163  ? 350 ARG A O    1 
ATOM   5228 C  CB   . ARG A 1 361 ? -36.44  -10.362 71.809 1   40.163  ? 350 ARG A CB   1 
ATOM   5229 C  CG   . ARG A 1 361 ? -35.424 -11.42  72.193 1   40.42   ? 350 ARG A CG   1 
ATOM   5230 C  CD   . ARG A 1 361 ? -35.837 -12.366 73.316 1   42.427  ? 350 ARG A CD   1 
ATOM   5231 N  NE   . ARG A 1 361 ? -36.135 -11.554 74.523 1   43.545  ? 350 ARG A NE   1 
ATOM   5232 C  CZ   . ARG A 1 361 ? -36.767 -12.014 75.613 1   47.683  ? 350 ARG A CZ   1 
ATOM   5233 N  NH1  . ARG A 1 361 ? -37.199 -13.276 75.717 1   52.138  ? 350 ARG A NH1  1 
ATOM   5234 N  NH2  . ARG A 1 361 ? -36.921 -11.26  76.662 1   40.399  ? 350 ARG A NH2  1 
ATOM   5235 H  H    . ARG A 1 361 ? -34.709 -8.818  71.49  1   39.781  ? 350 ARG A H    1 
ATOM   5236 H  HA   . ARG A 1 361 ? -35.945 -10.485 69.785 1   40.696  ? 350 ARG A HA   1 
ATOM   5237 H  HB2  . ARG A 1 361 ? -36.431 -9.648  72.481 1   40.725  ? 350 ARG A HB2  1 
ATOM   5238 H  HB3  . ARG A 1 361 ? -37.335 -10.765 71.812 1   40.744  ? 350 ARG A HB3  1 
ATOM   5239 H  HG2  . ARG A 1 361 ? -35.215 -11.957 71.398 1   40.816  ? 350 ARG A HG2  1 
ATOM   5240 H  HG3  . ARG A 1 361 ? -34.591 -10.971 72.457 1   40.804  ? 350 ARG A HG3  1 
ATOM   5241 H  HD2  . ARG A 1 361 ? -36.632 -12.874 73.056 1   42.225  ? 350 ARG A HD2  1 
ATOM   5242 H  HD3  . ARG A 1 361 ? -35.113 -12.995 73.513 1   42.225  ? 350 ARG A HD3  1 
ATOM   5243 H  HE   . ARG A 1 361 ? -35.89  -10.719 74.525 1   44.112  ? 350 ARG A HE   1 
ATOM   5244 H  HH11 . ARG A 1 361 ? -36.643 -13.946 75.565 1   50.67   ? 350 ARG A HH11 1 
ATOM   5245 H  HH12 . ARG A 1 361 ? -38.041 -13.434 75.94  1   50.7    ? 350 ARG A HH12 1 
ATOM   5246 H  HH21 . ARG A 1 361 ? -36.451 -10.515 76.743 1   42.554  ? 350 ARG A HH21 1 
ATOM   5247 H  HH22 . ARG A 1 361 ? -37.495 -11.495 77.292 1   42.598  ? 350 ARG A HH22 1 
ATOM   5248 N  N    . ALA A 1 362 ? -38.41  -9.597  69.49  1   47.269  ? 351 ALA A N    1 
ATOM   5249 C  CA   . ALA A 1 362 ? -39.521 -9.036  68.696 1   43.688  ? 351 ALA A CA   1 
ATOM   5250 C  C    . ALA A 1 362 ? -40.243 -7.871  69.398 1   31.446  ? 351 ALA A C    1 
ATOM   5251 O  O    . ALA A 1 362 ? -40.646 -6.864  68.803 1   37.982  ? 351 ALA A O    1 
ATOM   5252 C  CB   . ALA A 1 362 ? -40.423 -10.211 68.432 1   44.55   ? 351 ALA A CB   1 
ATOM   5253 H  H    . ALA A 1 362 ? -38.478 -10.463 69.772 1   44.413  ? 351 ALA A H    1 
ATOM   5254 H  HA   . ALA A 1 362 ? -39.152 -8.702  67.831 1   41.91   ? 351 ALA A HA   1 
ATOM   5255 H  HB1  . ALA A 1 362 ? -39.916 -10.925 68.01  1   44.31   ? 351 ALA A HB1  1 
ATOM   5256 H  HB2  . ALA A 1 362 ? -40.795 -10.533 69.27  1   44.297  ? 351 ALA A HB2  1 
ATOM   5257 H  HB3  . ALA A 1 362 ? -41.146 -9.941  67.842 1   44.296  ? 351 ALA A HB3  1 
ATOM   5258 N  N    . THR A 1 363 ? -40.329 -7.936  70.73  1   32.674  ? 352 THR A N    1 
ATOM   5259 C  CA   . THR A 1 363 ? -40.934 -6.844  71.453 1   39.235  ? 352 THR A CA   1 
ATOM   5260 C  C    . THR A 1 363 ? -40.257 -5.525  71.07  1   44.53   ? 352 THR A C    1 
ATOM   5261 O  O    . THR A 1 363 ? -40.897 -4.568  70.665 1   37.992  ? 352 THR A O    1 
ATOM   5262 C  CB   . THR A 1 363 ? -40.832 -7.109  72.952 1   48.646  ? 352 THR A CB   1 
ATOM   5263 O  OG1  . THR A 1 363 ? -41.545 -8.306  73.187 1   39.463  ? 352 THR A OG1  1 
ATOM   5264 C  CG2  . THR A 1 363 ? -41.477 -5.993  73.756 1   48.242  ? 352 THR A CG2  1 
ATOM   5265 H  H    . THR A 1 363 ? -40.016 -8.664  71.186 1   33.967  ? 352 THR A H    1 
ATOM   5266 H  HA   . THR A 1 363 ? -41.883 -6.796  71.207 1   40.334  ? 352 THR A HA   1 
ATOM   5267 H  HB   . THR A 1 363 ? -39.89  -7.223  73.223 1   44.803  ? 352 THR A HB   1 
ATOM   5268 H  HG1  . THR A 1 363 ? -42.37  -8.202  72.945 0   39.37   ? 352 THR A HG1  1 
ATOM   5269 H  HG21 . THR A 1 363 ? -41.985 -6.375  74.491 1   48.263  ? 352 THR A HG21 1 
ATOM   5270 H  HG22 . THR A 1 363 ? -42.074 -5.481  73.184 1   48.21   ? 352 THR A HG22 1 
ATOM   5271 H  HG23 . THR A 1 363 ? -40.785 -5.413  74.111 1   48.323  ? 352 THR A HG23 1 
ATOM   5272 N  N    . PHE A 1 364 ? -38.92  -5.45   71.241 1   47.164  ? 353 PHE A N    1 
ATOM   5273 C  CA   . PHE A 1 364 ? -38.217 -4.209  70.998 1   34.846  ? 353 PHE A CA   1 
ATOM   5274 C  C    . PHE A 1 364 ? -38.333 -3.916  69.517 1   28.377  ? 353 PHE A C    1 
ATOM   5275 O  O    . PHE A 1 364 ? -38.506 -2.762  69.104 1   31.328  ? 353 PHE A O    1 
ATOM   5276 C  CB   . PHE A 1 364 ? -36.73  -4.318  71.415 1   41.688  ? 353 PHE A CB   1 
ATOM   5277 C  CG   . PHE A 1 364 ? -35.949 -3.08   71.026 1   34.52   ? 353 PHE A CG   1 
ATOM   5278 C  CD1  . PHE A 1 364 ? -35.465 -2.931  69.724 1   36.666  ? 353 PHE A CD1  1 
ATOM   5279 C  CD2  . PHE A 1 364 ? -35.772 -2.05   71.929 1   37.747  ? 353 PHE A CD2  1 
ATOM   5280 C  CE1  . PHE A 1 364 ? -34.795 -1.767  69.352 1   39.763  ? 353 PHE A CE1  1 
ATOM   5281 C  CE2  . PHE A 1 364 ? -35.074 -0.917  71.566 1   39.695  ? 353 PHE A CE2  1 
ATOM   5282 C  CZ   . PHE A 1 364 ? -34.654 -0.748  70.249 1   37.814  ? 353 PHE A CZ   1 
ATOM   5283 H  H    . PHE A 1 364 ? -38.45  -6.184  71.515 1   43.322  ? 353 PHE A H    1 
ATOM   5284 H  HA   . PHE A 1 364 ? -38.652 -3.479  71.514 1   36.798  ? 353 PHE A HA   1 
ATOM   5285 H  HB2  . PHE A 1 364 ? -36.681 -4.44   72.388 1   38.351  ? 353 PHE A HB2  1 
ATOM   5286 H  HB3  . PHE A 1 364 ? -36.333 -5.103  70.977 1   38.354  ? 353 PHE A HB3  1 
ATOM   5287 H  HD1  . PHE A 1 364 ? -35.609 -3.614  69.089 1   36.856  ? 353 PHE A HD1  1 
ATOM   5288 H  HD2  . PHE A 1 364 ? -36.096 -2.14   72.811 1   37.45   ? 353 PHE A HD2  1 
ATOM   5289 H  HE1  . PHE A 1 364 ? -34.473 -1.669  68.47  1   38.508  ? 353 PHE A HE1  1 
ATOM   5290 H  HE2  . PHE A 1 364 ? -34.967 -0.214  72.187 1   38.763  ? 353 PHE A HE2  1 
ATOM   5291 H  HZ   . PHE A 1 364 ? -34.156 0.017   70.012 1   38.665  ? 353 PHE A HZ   1 
ATOM   5292 N  N    . ALA A 1 365 ? -38.168 -4.969  68.713 1   31.082  ? 354 ALA A N    1 
ATOM   5293 C  CA   . ALA A 1 365 ? -38.1   -4.766  67.26  1   34.729  ? 354 ALA A CA   1 
ATOM   5294 C  C    . ALA A 1 365 ? -39.397 -4.139  66.743 1   36.254  ? 354 ALA A C    1 
ATOM   5295 O  O    . ALA A 1 365 ? -39.379 -3.192  65.914 1   36.74   ? 354 ALA A O    1 
ATOM   5296 C  CB   . ALA A 1 365 ? -37.658 -6.046  66.496 1   36.797  ? 354 ALA A CB   1 
ATOM   5297 H  H    . ALA A 1 365 ? -38.089 -5.814  69.054 1   31.296  ? 354 ALA A H    1 
ATOM   5298 H  HA   . ALA A 1 365 ? -37.387 -4.085  67.109 1   34.567  ? 354 ALA A HA   1 
ATOM   5299 H  HB1  . ALA A 1 365 ? -36.776 -6.319  66.799 1   36.188  ? 354 ALA A HB1  1 
ATOM   5300 H  HB2  . ALA A 1 365 ? -38.292 -6.763  66.666 1   36.188  ? 354 ALA A HB2  1 
ATOM   5301 H  HB3  . ALA A 1 365 ? -37.628 -5.864  65.542 1   36.188  ? 354 ALA A HB3  1 
ATOM   5302 N  N    . GLN A 1 366 ? -40.542 -4.647  67.257 1   38.902  ? 355 GLN A N    1 
ATOM   5303 C  CA   . GLN A 1 366 ? -41.844 -4.137  66.801 1   35.743  ? 355 GLN A CA   1 
ATOM   5304 C  C    . GLN A 1 366 ? -42.045 -2.704  67.272 1   34.076  ? 355 GLN A C    1 
ATOM   5305 O  O    . GLN A 1 366 ? -42.479 -1.863  66.515 1   34.307  ? 355 GLN A O    1 
ATOM   5306 C  CB   . GLN A 1 366 ? -43.034 -4.965  67.326 1   40.906  ? 355 GLN A CB   1 
ATOM   5307 C  CG   . GLN A 1 366 ? -44.395 -4.561  66.742 1   41.756  ? 355 GLN A CG   1 
ATOM   5308 C  CD   . GLN A 1 366 ? -44.458 -4.417  65.233 1   41.065  ? 355 GLN A CD   1 
ATOM   5309 O  OE1  . GLN A 1 366 ? -45.151 -3.568  64.69  1   51.989  ? 355 GLN A OE1  1 
ATOM   5310 N  NE2  . GLN A 1 366 ? -43.738 -5.254  64.531 1   44.74   ? 355 GLN A NE2  1 
ATOM   5311 H  H    . GLN A 1 366 ? -40.516 -5.311  67.884 1   37.47   ? 355 GLN A H    1 
ATOM   5312 H  HA   . GLN A 1 366 ? -41.848 -4.147  65.812 1   36.956  ? 355 GLN A HA   1 
ATOM   5313 H  HB2  . GLN A 1 366 ? -42.87  -5.909  67.121 1   39.853  ? 355 GLN A HB2  1 
ATOM   5314 H  HB3  . GLN A 1 366 ? -43.069 -4.877  68.301 1   39.826  ? 355 GLN A HB3  1 
ATOM   5315 H  HG2  . GLN A 1 366 ? -45.058 -5.235  67.001 1   41.396  ? 355 GLN A HG2  1 
ATOM   5316 H  HG3  . GLN A 1 366 ? -44.674 -3.711  67.143 1   41.366  ? 355 GLN A HG3  1 
ATOM   5317 H  HE21 . GLN A 1 366 ? -43.211 -4.951  63.888 1   43.621  ? 355 GLN A HE21 1 
ATOM   5318 H  HE22 . GLN A 1 366 ? -43.775 -6.118  64.719 1   43.586  ? 355 GLN A HE22 1 
ATOM   5319 N  N    . PHE A 1 367 ? -41.642 -2.432  68.522 1   30.967  ? 356 PHE A N    1 
ATOM   5320 C  CA   . PHE A 1 367 ? -41.673 -1.087  69.064 1   34.127  ? 356 PHE A CA   1 
ATOM   5321 C  C    . PHE A 1 367 ? -40.852 -0.122  68.233 1   37.659  ? 356 PHE A C    1 
ATOM   5322 O  O    . PHE A 1 367 ? -41.289 1.004   67.982 1   40.518  ? 356 PHE A O    1 
ATOM   5323 C  CB   . PHE A 1 367 ? -41.315 -1.226  70.545 1   39.995  ? 356 PHE A CB   1 
ATOM   5324 C  CG   . PHE A 1 367 ? -41.307 0.116   71.229 1   47.663  ? 356 PHE A CG   1 
ATOM   5325 C  CD1  . PHE A 1 367 ? -42.5   0.666   71.708 1   52.163  ? 356 PHE A CD1  1 
ATOM   5326 C  CD2  . PHE A 1 367 ? -40.107 0.809   71.415 1   55.327  ? 356 PHE A CD2  1 
ATOM   5327 C  CE1  . PHE A 1 367 ? -42.506 1.914   72.321 1   54.734  ? 356 PHE A CE1  1 
ATOM   5328 C  CE2  . PHE A 1 367 ? -40.118 2.061   72.027 1   61.072  ? 356 PHE A CE2  1 
ATOM   5329 C  CZ   . PHE A 1 367 ? -41.315 2.6     72.487 1   58.881  ? 356 PHE A CZ   1 
ATOM   5330 H  H    . PHE A 1 367 ? -41.346 -3.114  69.054 1   32.551  ? 356 PHE A H    1 
ATOM   5331 H  HA   . PHE A 1 367 ? -42.617 -0.777  69.02  1   35.149  ? 356 PHE A HA   1 
ATOM   5332 H  HB2  . PHE A 1 367 ? -41.975 -1.81   70.981 1   40.166  ? 356 PHE A HB2  1 
ATOM   5333 H  HB3  . PHE A 1 367 ? -40.426 -1.637  70.623 1   40.138  ? 356 PHE A HB3  1 
ATOM   5334 H  HD1  . PHE A 1 367 ? -43.312 0.201   71.583 1   51.712  ? 356 PHE A HD1  1 
ATOM   5335 H  HD2  . PHE A 1 367 ? -39.298 0.446   71.091 1   54.626  ? 356 PHE A HD2  1 
ATOM   5336 H  HE1  . PHE A 1 367 ? -43.315 2.281   72.641 1   55.015  ? 356 PHE A HE1  1 
ATOM   5337 H  HE2  . PHE A 1 367 ? -39.31  2.531   72.153 1   58.782  ? 356 PHE A HE2  1 
ATOM   5338 H  HZ   . PHE A 1 367 ? -41.314 3.426   72.924 1   58.198  ? 356 PHE A HZ   1 
ATOM   5339 N  N    . GLN A 1 368 ? -39.654 -0.536  67.787 1   38.884  ? 357 GLN A N    1 
ATOM   5340 C  CA   . GLN A 1 368 ? -38.863 0.416   67.019 1   34.712  ? 357 GLN A CA   1 
ATOM   5341 C  C    . GLN A 1 368 ? -39.45  0.606   65.605 1   29.376  ? 357 GLN A C    1 
ATOM   5342 O  O    . GLN A 1 368 ? -39.384 1.712   64.991 1   33.92   ? 357 GLN A O    1 
ATOM   5343 C  CB   . GLN A 1 368 ? -37.395 -0.062  66.982 1   36.863  ? 357 GLN A CB   1 
ATOM   5344 C  CG   . GLN A 1 368 ? -36.496 0.699   66.024 1   37.433  ? 357 GLN A CG   1 
ATOM   5345 C  CD   . GLN A 1 368 ? -36.113 2.084   66.495 1   41.867  ? 357 GLN A CD   1 
ATOM   5346 O  OE1  . GLN A 1 368 ? -35.053 2.31    67.078 1   40.85   ? 357 GLN A OE1  1 
ATOM   5347 N  NE2  . GLN A 1 368 ? -36.971 3.039   66.252 1   36.87   ? 357 GLN A NE2  1 
ATOM   5348 H  H    . GLN A 1 368 ? -39.337 -1.376  67.955 1   37.565  ? 357 GLN A H    1 
ATOM   5349 H  HA   . GLN A 1 368 ? -38.887 1.289   67.488 1   34.857  ? 357 GLN A HA   1 
ATOM   5350 H  HB2  . GLN A 1 368 ? -37.024 0.009   67.886 1   36.497  ? 357 GLN A HB2  1 
ATOM   5351 H  HB3  . GLN A 1 368 ? -37.385 -1.011  66.734 1   36.503  ? 357 GLN A HB3  1 
ATOM   5352 H  HG2  . GLN A 1 368 ? -35.672 0.188   65.9   1   38.151  ? 357 GLN A HG2  1 
ATOM   5353 H  HG3  . GLN A 1 368 ? -36.933 0.77    65.15  1   38.174  ? 357 GLN A HG3  1 
ATOM   5354 H  HE21 . GLN A 1 368 ? -36.783 3.872   66.49  1   38.347  ? 357 GLN A HE21 1 
ATOM   5355 H  HE22 . GLN A 1 368 ? -37.74  2.858   65.851 1   38.287  ? 357 GLN A HE22 1 
ATOM   5356 N  N    . ARG A 1 369 ? -39.895 -0.494  64.998 1   29.93   ? 358 ARG A N    1 
ATOM   5357 C  CA   . ARG A 1 369 ? -40.671 -0.44   63.737 1   39.825  ? 358 ARG A CA   1 
ATOM   5358 C  C    . ARG A 1 369 ? -41.856 0.532   63.803 1   36.665  ? 358 ARG A C    1 
ATOM   5359 O  O    . ARG A 1 369 ? -42.051 1.36    62.908 1   38.051  ? 358 ARG A O    1 
ATOM   5360 C  CB   . ARG A 1 369 ? -41.298 -1.785  63.342 1   48.927  ? 358 ARG A CB   1 
ATOM   5361 C  CG   . ARG A 1 369 ? -40.416 -2.644  62.43  1   45.676  ? 358 ARG A CG   1 
ATOM   5362 C  CD   . ARG A 1 369 ? -40.606 -4.102  62.716 1   49.483  ? 358 ARG A CD   1 
ATOM   5363 N  NE   . ARG A 1 369 ? -39.776 -4.964  61.878 1   49.996  ? 358 ARG A NE   1 
ATOM   5364 C  CZ   . ARG A 1 369 ? -39.934 -5.166  60.587 1   50.676  ? 358 ARG A CZ   1 
ATOM   5365 N  NH1  . ARG A 1 369 ? -41.015 -4.847  59.916 1   48.071  ? 358 ARG A NH1  1 
ATOM   5366 N  NH2  . ARG A 1 369 ? -38.985 -5.762  59.933 1   39.586  ? 358 ARG A NH2  1 
ATOM   5367 H  H    . ARG A 1 369 ? -39.711 -1.311  65.363 1   31.907  ? 358 ARG A H    1 
ATOM   5368 H  HA   . ARG A 1 369 ? -40.063 -0.146  63.012 1   38.63   ? 358 ARG A HA   1 
ATOM   5369 H  HB2  . ARG A 1 369 ? -41.494 -2.291  64.159 1   45.808  ? 358 ARG A HB2  1 
ATOM   5370 H  HB3  . ARG A 1 369 ? -42.15  -1.617  62.886 1   45.874  ? 358 ARG A HB3  1 
ATOM   5371 H  HG2  . ARG A 1 369 ? -40.646 -2.466  61.492 1   47.247  ? 358 ARG A HG2  1 
ATOM   5372 H  HG3  . ARG A 1 369 ? -39.473 -2.407  62.568 1   47.15   ? 358 ARG A HG3  1 
ATOM   5373 H  HD2  . ARG A 1 369 ? -40.395 -4.272  63.657 1   48.606  ? 358 ARG A HD2  1 
ATOM   5374 H  HD3  . ARG A 1 369 ? -41.546 -4.329  62.574 1   48.645  ? 358 ARG A HD3  1 
ATOM   5375 H  HE   . ARG A 1 369 ? -39.118 -5.383  62.266 1   49.854  ? 358 ARG A HE   1 
ATOM   5376 H  HH11 . ARG A 1 369 ? -41.809 -4.922  60.297 1   48.837  ? 358 ARG A HH11 1 
ATOM   5377 H  HH12 . ARG A 1 369 ? -40.945 -4.563  59.082 1   48.761  ? 358 ARG A HH12 1 
ATOM   5378 H  HH21 . ARG A 1 369 ? -38.631 -6.506  60.252 1   42.788  ? 358 ARG A HH21 1 
ATOM   5379 H  HH22 . ARG A 1 369 ? -38.698 -5.42   59.17  1   42.787  ? 358 ARG A HH22 1 
ATOM   5380 N  N    . GLN A 1 370 ? -42.548 0.541   64.933 1   41.787  ? 359 GLN A N    1 
ATOM   5381 C  CA   . GLN A 1 370 ? -43.695 1.426   65.073 1   47.454  ? 359 GLN A CA   1 
ATOM   5382 C  C    . GLN A 1 370 ? -43.223 2.859   65.143 1   46.692  ? 359 GLN A C    1 
ATOM   5383 O  O    . GLN A 1 370 ? -43.908 3.707   64.541 1   40.264  ? 359 GLN A O    1 
ATOM   5384 C  CB   . GLN A 1 370 ? -44.617 1.232   66.286 1   49.673  ? 359 GLN A CB   1 
ATOM   5385 C  CG   . GLN A 1 370 ? -45.819 0.334   65.992 1   73.317  ? 359 GLN A CG   1 
ATOM   5386 C  CD   . GLN A 1 370 ? -46.352 -0.247  67.282 1   86.46   ? 359 GLN A CD   1 
ATOM   5387 O  OE1  . GLN A 1 370 ? -46.291 -1.464  67.571 1   73.932  ? 359 GLN A OE1  1 
ATOM   5388 N  NE2  . GLN A 1 370 ? -46.791 0.702   68.101 1   72.617  ? 359 GLN A NE2  1 
ATOM   5389 H  H    . GLN A 1 370 ? -42.317 -0.01   65.625 1   41.493  ? 359 GLN A H    1 
ATOM   5390 H  HA   . GLN A 1 370 ? -44.254 1.328   64.26  1   46.513  ? 359 GLN A HA   1 
ATOM   5391 H  HB2  . GLN A 1 370 ? -44.095 0.839   67.017 1   53.905  ? 359 GLN A HB2  1 
ATOM   5392 H  HB3  . GLN A 1 370 ? -44.94  2.107   66.586 1   53.75   ? 359 GLN A HB3  1 
ATOM   5393 H  HG2  . GLN A 1 370 ? -46.523 0.855   65.551 1   69.681  ? 359 GLN A HG2  1 
ATOM   5394 H  HG3  . GLN A 1 370 ? -45.551 -0.393  65.39  1   69.676  ? 359 GLN A HG3  1 
ATOM   5395 H  HE21 . GLN A 1 370 ? -46.602 0.661   68.967 1   76.62   ? 359 GLN A HE21 1 
ATOM   5396 H  HE22 . GLN A 1 370 ? -47.273 1.376   67.783 1   76.596  ? 359 GLN A HE22 1 
ATOM   5397 N  N    . ALA A 1 371 ? -42.103 3.101   65.871 1   41.85   ? 360 ALA A N    1 
ATOM   5398 C  CA   . ALA A 1 371 ? -41.57  4.473   66     1   37.044  ? 360 ALA A CA   1 
ATOM   5399 C  C    . ALA A 1 371 ? -41.145 5.015   64.625 1   38.919  ? 360 ALA A C    1 
ATOM   5400 O  O    . ALA A 1 371 ? -41.233 6.199   64.323 1   38.708  ? 360 ALA A O    1 
ATOM   5401 C  CB   . ALA A 1 371 ? -40.432 4.531   67.004 1   46.445  ? 360 ALA A CB   1 
ATOM   5402 H  H    . ALA A 1 371 ? -41.672 2.415   66.293 1   41.811  ? 360 ALA A H    1 
ATOM   5403 H  HA   . ALA A 1 371 ? -42.31  5.051   66.333 1   40.126  ? 360 ALA A HA   1 
ATOM   5404 H  HB1  . ALA A 1 371 ? -40.752 4.245   67.877 1   43.439  ? 360 ALA A HB1  1 
ATOM   5405 H  HB2  . ALA A 1 371 ? -39.713 3.943   66.718 1   43.439  ? 360 ALA A HB2  1 
ATOM   5406 H  HB3  . ALA A 1 371 ? -40.097 5.441   67.067 1   43.439  ? 360 ALA A HB3  1 
ATOM   5407 N  N    . ILE A 1 372 ? -40.656 4.123   63.77  1   39.929  ? 361 ILE A N    1 
ATOM   5408 C  CA   . ILE A 1 372 ? -40.165 4.534   62.457 1   40.87   ? 361 ILE A CA   1 
ATOM   5409 C  C    . ILE A 1 372 ? -41.379 4.793   61.564 1   42.522  ? 361 ILE A C    1 
ATOM   5410 O  O    . ILE A 1 372 ? -41.322 5.668   60.727 1   41.688  ? 361 ILE A O    1 
ATOM   5411 C  CB   . ILE A 1 372 ? -39.276 3.428   61.861 1   34.638  ? 361 ILE A CB   1 
ATOM   5412 C  CG1  . ILE A 1 372 ? -37.901 3.299   62.58  1   42.815  ? 361 ILE A CG1  1 
ATOM   5413 C  CG2  . ILE A 1 372 ? -39.073 3.573   60.345 1   39.807  ? 361 ILE A CG2  1 
ATOM   5414 C  CD1  . ILE A 1 372 ? -37.167 1.999   62.282 1   35.476  ? 361 ILE A CD1  1 
ATOM   5415 H  H    . ILE A 1 372 ? -40.612 3.241   64.005 1   39.868  ? 361 ILE A H    1 
ATOM   5416 H  HA   . ILE A 1 372 ? -39.643 5.355   62.546 1   39.754  ? 361 ILE A HA   1 
ATOM   5417 H  HB   . ILE A 1 372 ? -39.746 2.583   62.004 1   38.144  ? 361 ILE A HB   1 
ATOM   5418 H  HG12 . ILE A 1 372 ? -37.334 4.049   62.308 1   39.102  ? 361 ILE A HG12 1 
ATOM   5419 H  HG13 . ILE A 1 372 ? -38.043 3.367   63.546 1   39.078  ? 361 ILE A HG13 1 
ATOM   5420 H  HG21 . ILE A 1 372 ? -38.434 2.911   60.036 1   38.215  ? 361 ILE A HG21 1 
ATOM   5421 H  HG22 . ILE A 1 372 ? -38.737 4.462   60.144 1   38.242  ? 361 ILE A HG22 1 
ATOM   5422 H  HG23 . ILE A 1 372 ? -39.919 3.437   59.886 1   38.246  ? 361 ILE A HG23 1 
ATOM   5423 H  HD11 . ILE A 1 372 ? -37.779 1.246   62.387 1   37.556  ? 361 ILE A HD11 1 
ATOM   5424 H  HD12 . ILE A 1 372 ? -36.421 1.897   62.903 1   37.513  ? 361 ILE A HD12 1 
ATOM   5425 H  HD13 . ILE A 1 372 ? -36.826 2.014   61.368 1   37.514  ? 361 ILE A HD13 1 
ATOM   5426 N  N    . ASP A 1 373 ? -42.425 3.957   61.677 1   50.494  ? 362 ASP A N    1 
ATOM   5427 C  CA   . ASP A 1 373 ? -43.71  4.203   61.018 1   47.466  ? 362 ASP A CA   1 
ATOM   5428 C  C    . ASP A 1 373 ? -44.21  5.62    61.346 1   41.243  ? 362 ASP A C    1 
ATOM   5429 O  O    . ASP A 1 373 ? -44.548 6.406   60.455 1   43.526  ? 362 ASP A O    1 
ATOM   5430 C  CB   . ASP A 1 373 ? -44.684 3.097   61.409 1   44.415  ? 362 ASP A CB   1 
ATOM   5431 C  CG   . ASP A 1 373 ? -44.455 1.772   60.694 1   40.29   ? 362 ASP A CG   1 
ATOM   5432 O  OD1  . ASP A 1 373 ? -43.656 1.82    59.728 1   46.449  ? 362 ASP A OD1  1 
ATOM   5433 O  OD2  . ASP A 1 373 ? -45.031 0.707   61.137 1   60.924  ? 362 ASP A OD2  1 
ATOM   5434 H  H    . ASP A 1 373 ? -42.331 3.196   62.175 1   47.631  ? 362 ASP A H    1 
ATOM   5435 H  HA   . ASP A 1 373 ? -43.567 4.15    60.046 1   46.219  ? 362 ASP A HA   1 
ATOM   5436 H  HB2  . ASP A 1 373 ? -44.626 2.937   62.372 1   44.083  ? 362 ASP A HB2  1 
ATOM   5437 H  HB3  . ASP A 1 373 ? -45.595 3.397   61.208 1   44.076  ? 362 ASP A HB3  1 
ATOM   5438 N  N    . ARG A 1 374 ? -44.181 5.984   62.632 1   43.745  ? 363 ARG A N    1 
ATOM   5439 C  CA   . ARG A 1 374 ? -44.683 7.293   62.99  1   49.354  ? 363 ARG A CA   1 
ATOM   5440 C  C    . ARG A 1 374 ? -43.854 8.393   62.357 1   44.609  ? 363 ARG A C    1 
ATOM   5441 O  O    . ARG A 1 374 ? -44.358 9.483   62.212 1   43.618  ? 363 ARG A O    1 
ATOM   5442 C  CB   . ARG A 1 374 ? -44.64  7.582   64.483 1   55.572  ? 363 ARG A CB   1 
ATOM   5443 C  CG   . ARG A 1 374 ? -45.669 6.806   65.287 1   66.375  ? 363 ARG A CG   1 
ATOM   5444 C  CD   . ARG A 1 374 ? -45.722 7.404   66.706 1   70.559  ? 363 ARG A CD   1 
ATOM   5445 N  NE   . ARG A 1 374 ? -44.536 7.085   67.522 1   84.348  ? 363 ARG A NE   1 
ATOM   5446 C  CZ   . ARG A 1 374 ? -44.292 5.943   68.212 1   78.791  ? 363 ARG A CZ   1 
ATOM   5447 N  NH1  . ARG A 1 374 ? -45.209 4.982   68.307 1   66.527  ? 363 ARG A NH1  1 
ATOM   5448 N  NH2  . ARG A 1 374 ? -43.131 5.776   68.834 1   66.049  ? 363 ARG A NH2  1 
ATOM   5449 H  H    . ARG A 1 374 ? -43.857 5.424   63.278 1   44.441  ? 363 ARG A H    1 
ATOM   5450 H  HA   . ARG A 1 374 ? -45.618 7.37    62.671 1   48.29   ? 363 ARG A HA   1 
ATOM   5451 H  HB2  . ARG A 1 374 ? -43.746 7.363   64.821 1   56.337  ? 363 ARG A HB2  1 
ATOM   5452 H  HB3  . ARG A 1 374 ? -44.787 8.541   64.625 1   56.351  ? 363 ARG A HB3  1 
ATOM   5453 H  HG2  . ARG A 1 374 ? -46.552 6.882   64.864 1   64.62   ? 363 ARG A HG2  1 
ATOM   5454 H  HG3  . ARG A 1 374 ? -45.412 5.86    65.337 1   64.62   ? 363 ARG A HG3  1 
ATOM   5455 H  HD2  . ARG A 1 374 ? -45.805 8.376   66.634 1   72.325  ? 363 ARG A HD2  1 
ATOM   5456 H  HD3  . ARG A 1 374 ? -46.52  7.077   67.162 1   72.341  ? 363 ARG A HD3  1 
ATOM   5457 H  HE   . ARG A 1 374 ? -43.921 7.699   67.57  1   79.437  ? 363 ARG A HE   1 
ATOM   5458 H  HH11 . ARG A 1 374 ? -45.732 4.799   67.617 1   70.085  ? 363 ARG A HH11 1 
ATOM   5459 H  HH12 . ARG A 1 374 ? -45.291 4.528   69.062 1   70.055  ? 363 ARG A HH12 1 
ATOM   5460 H  HH21 . ARG A 1 374 ? -42.548 6.44    68.867 1   69.91   ? 363 ARG A HH21 1 
ATOM   5461 H  HH22 . ARG A 1 374 ? -42.945 5       69.214 1   69.757  ? 363 ARG A HH22 1 
ATOM   5462 N  N    . LEU A 1 375 ? -42.534 8.169   62.188 1   50.232  ? 364 LEU A N    1 
ATOM   5463 C  CA   . LEU A 1 375 ? -41.642 9.191   61.667 1   39.692  ? 364 LEU A CA   1 
ATOM   5464 C  C    . LEU A 1 375 ? -41.971 9.35    60.19  1   37.564  ? 364 LEU A C    1 
ATOM   5465 O  O    . LEU A 1 375 ? -42.013 10.43   59.675 1   43.303  ? 364 LEU A O    1 
ATOM   5466 C  CB   . LEU A 1 375 ? -40.133 8.937   61.806 1   44.944  ? 364 LEU A CB   1 
ATOM   5467 C  CG   . LEU A 1 375 ? -39.547 9.087   63.21  1   50.716  ? 364 LEU A CG   1 
ATOM   5468 C  CD1  . LEU A 1 375 ? -38.12  8.656   63.266 1   50.216  ? 364 LEU A CD1  1 
ATOM   5469 C  CD2  . LEU A 1 375 ? -39.65  10.52   63.631 1   60.148  ? 364 LEU A CD2  1 
ATOM   5470 H  H    . LEU A 1 375 ? -42.182 7.358   62.419 1   46.249  ? 364 LEU A H    1 
ATOM   5471 H  HA   . LEU A 1 375 ? -41.863 10.044  62.119 1   42.258  ? 364 LEU A HA   1 
ATOM   5472 H  HB2  . LEU A 1 375 ? -39.947 8.022   61.49  1   44.923  ? 364 LEU A HB2  1 
ATOM   5473 H  HB3  . LEU A 1 375 ? -39.66  9.557   61.205 1   44.959  ? 364 LEU A HB3  1 
ATOM   5474 H  HG   . LEU A 1 375 ? -40.076 8.53    63.838 1   51.056  ? 364 LEU A HG   1 
ATOM   5475 H  HD11 . LEU A 1 375 ? -38.048 7.732   62.976 1   50.376  ? 364 LEU A HD11 1 
ATOM   5476 H  HD12 . LEU A 1 375 ? -37.792 8.735   64.177 1   50.409  ? 364 LEU A HD12 1 
ATOM   5477 H  HD13 . LEU A 1 375 ? -37.587 9.221   62.681 1   50.376  ? 364 LEU A HD13 1 
ATOM   5478 H  HD21 . LEU A 1 375 ? -40.577 10.737  63.825 1   56.856  ? 364 LEU A HD21 1 
ATOM   5479 H  HD22 . LEU A 1 375 ? -39.327 11.094  62.916 1   56.898  ? 364 LEU A HD22 1 
ATOM   5480 H  HD23 . LEU A 1 375 ? -39.113 10.664  64.428 1   56.961  ? 364 LEU A HD23 1 
ATOM   5481 N  N    . ALA A 1 376 ? -42.075 8.259   59.471 1   38.021  ? 365 ALA A N    1 
ATOM   5482 C  CA   . ALA A 1 376 ? -42.38  8.34    58.05  1   45.79   ? 365 ALA A CA   1 
ATOM   5483 C  C    . ALA A 1 376 ? -43.734 9.009   57.801 1   50.141  ? 365 ALA A C    1 
ATOM   5484 O  O    . ALA A 1 376 ? -43.925 9.627   56.77  1   44.583  ? 365 ALA A O    1 
ATOM   5485 C  CB   . ALA A 1 376 ? -42.381 6.933   57.473 1   43.107  ? 365 ALA A CB   1 
ATOM   5486 H  H    . ALA A 1 376 ? -41.952 7.44    59.857 1   39.652  ? 365 ALA A H    1 
ATOM   5487 H  HA   . ALA A 1 376 ? -41.671 8.88    57.604 1   44.363  ? 365 ALA A HA   1 
ATOM   5488 H  HB1  . ALA A 1 376 ? -41.599 6.449   57.787 1   43.818  ? 365 ALA A HB1  1 
ATOM   5489 H  HB2  . ALA A 1 376 ? -43.183 6.463   57.758 1   43.898  ? 365 ALA A HB2  1 
ATOM   5490 H  HB3  . ALA A 1 376 ? -42.363 6.978   56.503 1   43.872  ? 365 ALA A HB3  1 
ATOM   5491 N  N    . GLN A 1 377 ? -44.693 8.775   58.69  1   52.252  ? 366 GLN A N    1 
ATOM   5492 C  CA   . GLN A 1 377 ? -45.969 9.459   58.576 1   59.14   ? 366 GLN A CA   1 
ATOM   5493 C  C    . GLN A 1 377 ? -45.77  10.957  58.82  1   61.273  ? 366 GLN A C    1 
ATOM   5494 O  O    . GLN A 1 377 ? -46.241 11.767  58.05  1   54.827  ? 366 GLN A O    1 
ATOM   5495 C  CB   . GLN A 1 377 ? -46.969 8.8     59.518 1   66.272  ? 366 GLN A CB   1 
ATOM   5496 C  CG   . GLN A 1 377 ? -48.378 9.355   59.374 1   93.059  ? 366 GLN A CG   1 
ATOM   5497 C  CD   . GLN A 1 377 ? -49     9.553   60.737 1   107.253 ? 366 GLN A CD   1 
ATOM   5498 O  OE1  . GLN A 1 377 ? -49.246 8.583   61.468 1   104.122 ? 366 GLN A OE1  1 
ATOM   5499 N  NE2  . GLN A 1 377 ? -49.179 10.811  61.121 1   90.289  ? 366 GLN A NE2  1 
ATOM   5500 H  H    . GLN A 1 377 ? -44.56  8.181   59.372 1   53.103  ? 366 GLN A H    1 
ATOM   5501 H  HA   . GLN A 1 377 ? -46.301 9.338   57.649 1   59.165  ? 366 GLN A HA   1 
ATOM   5502 H  HB2  . GLN A 1 377 ? -46.985 7.837   59.338 1   69.851  ? 366 GLN A HB2  1 
ATOM   5503 H  HB3  . GLN A 1 377 ? -46.664 8.927   60.441 1   69.997  ? 366 GLN A HB3  1 
ATOM   5504 H  HG2  . GLN A 1 377 ? -48.354 10.211  58.895 1   88.642  ? 366 GLN A HG2  1 
ATOM   5505 H  HG3  . GLN A 1 377 ? -48.927 8.73    58.854 1   88.902  ? 366 GLN A HG3  1 
ATOM   5506 H  HE21 . GLN A 1 377 ? -49.822 11.008  61.7   1   95.191  ? 366 GLN A HE21 1 
ATOM   5507 H  HE22 . GLN A 1 377 ? -48.657 11.454  60.801 1   95.134  ? 366 GLN A HE22 1 
ATOM   5508 N  N    . GLN A 1 378 ? -45.006 11.343  59.843 1   62.542  ? 367 GLN A N    1 
ATOM   5509 C  CA   . GLN A 1 378 ? -44.702 12.743  60.083 1   51.564  ? 367 GLN A CA   1 
ATOM   5510 C  C    . GLN A 1 378 ? -43.99  13.39   58.903 1   49.497  ? 367 GLN A C    1 
ATOM   5511 O  O    . GLN A 1 378 ? -44.015 14.611  58.775 1   50.804  ? 367 GLN A O    1 
ATOM   5512 C  CB   . GLN A 1 378 ? -43.878 12.832  61.37  1   61.742  ? 367 GLN A CB   1 
ATOM   5513 C  CG   . GLN A 1 378 ? -43.182 14.166  61.657 1   64.415  ? 367 GLN A CG   1 
ATOM   5514 C  CD   . GLN A 1 378 ? -42.517 14.185  63.031 1   79.835  ? 367 GLN A CD   1 
ATOM   5515 O  OE1  . GLN A 1 378 ? -42.696 13.275  63.858 1   71.13   ? 367 GLN A OE1  1 
ATOM   5516 N  NE2  . GLN A 1 378 ? -41.762 15.241  63.324 1   68.89   ? 367 GLN A NE2  1 
ATOM   5517 H  H    . GLN A 1 378 ? -44.671 10.713  60.414 1   59.546  ? 367 GLN A H    1 
ATOM   5518 H  HA   . GLN A 1 378 ? -45.558 13.221  60.229 1   54.92   ? 367 GLN A HA   1 
ATOM   5519 H  HB2  . GLN A 1 378 ? -44.474 12.627  62.121 1   59.857  ? 367 GLN A HB2  1 
ATOM   5520 H  HB3  . GLN A 1 378 ? -43.196 12.13   61.343 1   59.745  ? 367 GLN A HB3  1 
ATOM   5521 H  HG2  . GLN A 1 378 ? -42.498 14.331  60.973 1   66.818  ? 367 GLN A HG2  1 
ATOM   5522 H  HG3  . GLN A 1 378 ? -43.838 14.893  61.608 1   66.969  ? 367 GLN A HG3  1 
ATOM   5523 H  HE21 . GLN A 1 378 ? -41.347 15.285  64.106 1   72.07   ? 367 GLN A HE21 1 
ATOM   5524 H  HE22 . GLN A 1 378 ? -41.674 15.9    62.736 1   72.032  ? 367 GLN A HE22 1 
ATOM   5525 N  N    . PHE A 1 379 ? -43.283 12.627  58.067 1   44.343  ? 368 PHE A N    1 
ATOM   5526 C  CA   . PHE A 1 379 ? -42.507 13.271  57.014 1   45.54   ? 368 PHE A CA   1 
ATOM   5527 C  C    . PHE A 1 379 ? -43.258 13.125  55.688 1   50.795  ? 368 PHE A C    1 
ATOM   5528 O  O    . PHE A 1 379 ? -42.695 13.442  54.647 1   42.315  ? 368 PHE A O    1 
ATOM   5529 C  CB   . PHE A 1 379 ? -41.047 12.746  56.88  1   49.144  ? 368 PHE A CB   1 
ATOM   5530 C  CG   . PHE A 1 379 ? -40.143 12.669  58.111 1   54.088  ? 368 PHE A CG   1 
ATOM   5531 C  CD1  . PHE A 1 379 ? -40.085 13.692  59.061 1   58.648  ? 368 PHE A CD1  1 
ATOM   5532 C  CD2  . PHE A 1 379 ? -39.343 11.546  58.345 1   53.249  ? 368 PHE A CD2  1 
ATOM   5533 C  CE1  . PHE A 1 379 ? -39.22  13.62   60.157 1   55.233  ? 368 PHE A CE1  1 
ATOM   5534 C  CE2  . PHE A 1 379 ? -38.478 11.484  59.436 1   49.059  ? 368 PHE A CE2  1 
ATOM   5535 C  CZ   . PHE A 1 379 ? -38.426 12.501  60.35  1   50.087  ? 368 PHE A CZ   1 
ATOM   5536 H  H    . PHE A 1 379 ? -43.256 11.719  58.159 1   46.075  ? 368 PHE A H    1 
ATOM   5537 H  HA   . PHE A 1 379 ? -42.454 14.241  57.223 1   46.907  ? 368 PHE A HA   1 
ATOM   5538 H  HB2  . PHE A 1 379 ? -41.095 11.846  56.487 1   49.424  ? 368 PHE A HB2  1 
ATOM   5539 H  HB3  . PHE A 1 379 ? -40.594 13.307  56.212 1   49.354  ? 368 PHE A HB3  1 
ATOM   5540 H  HD1  . PHE A 1 379 ? -40.608 14.467  58.934 1   56.621  ? 368 PHE A HD1  1 
ATOM   5541 H  HD2  . PHE A 1 379 ? -39.348 10.84   57.719 1   52.408  ? 368 PHE A HD2  1 
ATOM   5542 H  HE1  . PHE A 1 379 ? -39.198 14.325  60.782 1   54.602  ? 368 PHE A HE1  1 
ATOM   5543 H  HE2  . PHE A 1 379 ? -37.948 10.714  59.565 1   50.339  ? 368 PHE A HE2  1 
ATOM   5544 H  HZ   . PHE A 1 379 ? -37.86  12.441  61.102 1   50.947  ? 368 PHE A HZ   1 
ATOM   5545 N  N    . GLY A 1 380 ? -44.482 12.568  55.721 1   58.334  ? 369 GLY A N    1 
ATOM   5546 C  CA   . GLY A 1 380 ? -45.346 12.448  54.555 1   57.827  ? 369 GLY A CA   1 
ATOM   5547 C  C    . GLY A 1 380 ? -44.917 11.336  53.597 1   66.591  ? 369 GLY A C    1 
ATOM   5548 O  O    . GLY A 1 380 ? -45.021 11.455  52.379 1   55.562  ? 369 GLY A O    1 
ATOM   5549 H  H    . GLY A 1 380 ? -44.793 12.242  56.515 1   56.031  ? 369 GLY A H    1 
ATOM   5550 H  HA2  . GLY A 1 380 ? -46.267 12.274  54.861 1   59.77   ? 369 GLY A HA2  1 
ATOM   5551 H  HA3  . GLY A 1 380 ? -45.348 13.308  54.073 1   59.645  ? 369 GLY A HA3  1 
ATOM   5552 N  N    . LEU A 1 381 ? -44.463 10.21   54.138 1   68.628  ? 370 LEU A N    1 
ATOM   5553 C  CA   . LEU A 1 381 ? -43.941 9.152   53.288 1   63.432  ? 370 LEU A CA   1 
ATOM   5554 C  C    . LEU A 1 381 ? -44.725 7.87    53.526 1   63.746  ? 370 LEU A C    1 
ATOM   5555 O  O    . LEU A 1 381 ? -44.222 6.818   53.166 1   61.347  ? 370 LEU A O    1 
ATOM   5556 C  CB   . LEU A 1 381 ? -42.44  8.941   53.531 1   58.808  ? 370 LEU A CB   1 
ATOM   5557 C  CG   . LEU A 1 381 ? -41.554 10.161  53.249 1   59.463  ? 370 LEU A CG   1 
ATOM   5558 C  CD1  . LEU A 1 381 ? -40.203 9.979   53.898 1   61.636  ? 370 LEU A CD1  1 
ATOM   5559 C  CD2  . LEU A 1 381 ? -41.332 10.445  51.758 1   56.644  ? 370 LEU A CD2  1 
ATOM   5560 H  H    . LEU A 1 381 ? -44.48  10.091  55.044 1   66.873  ? 370 LEU A H    1 
ATOM   5561 H  HA   . LEU A 1 381 ? -44.074 9.417   52.344 1   63.552  ? 370 LEU A HA   1 
ATOM   5562 H  HB2  . LEU A 1 381 ? -42.314 8.674   54.471 1   59.996  ? 370 LEU A HB2  1 
ATOM   5563 H  HB3  . LEU A 1 381 ? -42.135 8.199   52.96  1   59.989  ? 370 LEU A HB3  1 
ATOM   5564 H  HG   . LEU A 1 381 ? -41.985 10.958  53.653 1   59.258  ? 370 LEU A HG   1 
ATOM   5565 H  HD11 . LEU A 1 381 ? -40.315 9.872   54.857 1   60.97   ? 370 LEU A HD11 1 
ATOM   5566 H  HD12 . LEU A 1 381 ? -39.65  10.76   53.724 1   60.958  ? 370 LEU A HD12 1 
ATOM   5567 H  HD13 . LEU A 1 381 ? -39.77  9.189   53.532 1   60.975  ? 370 LEU A HD13 1 
ATOM   5568 H  HD21 . LEU A 1 381 ? -42.17  10.725  51.352 1   57.611  ? 370 LEU A HD21 1 
ATOM   5569 H  HD22 . LEU A 1 381 ? -41.015 9.638   51.318 1   57.542  ? 370 LEU A HD22 1 
ATOM   5570 H  HD23 . LEU A 1 381 ? -40.67  11.149  51.656 1   57.751  ? 370 LEU A HD23 1 
ATOM   5571 N  N    . GLN A 1 382 ? -45.96  7.98    54.043 1   99.144  ? 371 GLN A N    1 
ATOM   5572 C  CA   . GLN A 1 382 ? -46.77  6.825   54.407 1   104.736 ? 371 GLN A CA   1 
ATOM   5573 C  C    . GLN A 1 382 ? -48.213 7.302   54.641 1   94.704  ? 371 GLN A C    1 
ATOM   5574 O  O    . GLN A 1 382 ? -48.476 7.755   55.782 1   99.347  ? 371 GLN A O    1 
ATOM   5575 C  CB   . GLN A 1 382 ? -46.175 6.13    55.64  1   108.492 ? 371 GLN A CB   1 
ATOM   5576 C  CG   . GLN A 1 382 ? -46.832 4.802   56.022 1   118.486 ? 371 GLN A CG   1 
ATOM   5577 C  CD   . GLN A 1 382 ? -46.097 4.022   57.103 1   111.181 ? 371 GLN A CD   1 
ATOM   5578 O  OE1  . GLN A 1 382 ? -45.077 3.358   56.856 1   93.474  ? 371 GLN A OE1  1 
ATOM   5579 N  NE2  . GLN A 1 382 ? -46.632 4.048   58.318 1   87.779  ? 371 GLN A NE2  1 
ATOM   5580 H  H    . GLN A 1 382 ? -46.315 8.813   54.166 1   89.65   ? 371 GLN A H    1 
ATOM   5581 H  HA   . GLN A 1 382 ? -46.766 6.189   53.647 1   101.861 ? 371 GLN A HA   1 
ATOM   5582 H  HB2  . GLN A 1 382 ? -45.223 5.969   55.476 1   109.152 ? 371 GLN A HB2  1 
ATOM   5583 H  HB3  . GLN A 1 382 ? -46.24  6.742   56.403 1   109.62  ? 371 GLN A HB3  1 
ATOM   5584 H  HG2  . GLN A 1 382 ? -47.747 4.975   56.331 1   114.038 ? 371 GLN A HG2  1 
ATOM   5585 H  HG3  . GLN A 1 382 ? -46.895 4.236   55.223 1   114.381 ? 371 GLN A HG3  1 
ATOM   5586 H  HE21 . GLN A 1 382 ? -46.467 3.387   58.887 1   94.48   ? 371 GLN A HE21 1 
ATOM   5587 H  HE22 . GLN A 1 382 ? -47.153 4.724   58.561 1   94.716  ? 371 GLN A HE22 1 
HETATM 5588 K  K    . K   B 2 .   ? -25.856 9.801   61.07  1   37.416  ? 401 K   A K    1 
HETATM 5589 K  K    . K   C 2 .   ? -31.209 20.485  52.774 1   63.741  ? 402 K   A K    1 
HETATM 5590 ZN ZN   . ZN  D 3 .   ? -19.74  8.748   64.502 1   33.742  ? 403 ZN  A ZN   1 
HETATM 5591 P  P    . PO4 E 4 .   ? 3.558   14.032  56.07  1   87.739  ? 404 PO4 A P    1 
HETATM 5592 O  O1   . PO4 E 4 .   ? 4.437   15.243  56.573 1   68.722  ? 404 PO4 A O1   1 
HETATM 5593 O  O2   . PO4 E 4 .   ? 3.33    14.149  54.543 1   76.772  ? 404 PO4 A O2   1 
HETATM 5594 O  O3   . PO4 E 4 .   ? 4.335   12.762  56.316 1   130.684 ? 404 PO4 A O3   1 
HETATM 5595 O  O4   . PO4 E 4 .   ? 2.178   13.92   56.827 1   67.564  ? 404 PO4 A O4   1 
HETATM 5596 O  O1   . TSN F 5 .   ? -19.267 10.514  64.286 1   40.576  ? 405 TSN A O1   1 
HETATM 5597 O  O2   . TSN F 5 .   ? -17.424 9.271   65.917 1   57.5    ? 405 TSN A O2   1 
HETATM 5598 O  O3   . TSN F 5 .   ? -15.552 10.836  72.693 1   58.915  ? 405 TSN A O3   1 
HETATM 5599 N  N1   . TSN F 5 .   ? -18.26  11.118  65.046 1   82.806  ? 405 TSN A N1   1 
HETATM 5600 N  N2   . TSN F 5 .   ? -16.091 15.09   77.556 1   64.907  ? 405 TSN A N2   1 
HETATM 5601 C  C1   . TSN F 5 .   ? -16.448 12.347  74.27  1   58.231  ? 405 TSN A C1   1 
HETATM 5602 C  C2   . TSN F 5 .   ? -15.242 12.553  74.938 1   48.179  ? 405 TSN A C2   1 
HETATM 5603 C  C3   . TSN F 5 .   ? -15.123 13.439  76     1   53.884  ? 405 TSN A C3   1 
HETATM 5604 C  C4   . TSN F 5 .   ? -16.215 14.198  76.492 1   49.268  ? 405 TSN A C4   1 
HETATM 5605 C  C5   . TSN F 5 .   ? -17.423 13.997  75.794 1   52.087  ? 405 TSN A C5   1 
HETATM 5606 C  C6   . TSN F 5 .   ? -17.525 13.106  74.729 1   54.965  ? 405 TSN A C6   1 
HETATM 5607 C  C7   . TSN F 5 .   ? -16.55  11.378  73.122 1   57.873  ? 405 TSN A C7   1 
HETATM 5608 C  C8   . TSN F 5 .   ? -17.896 10.93   72.524 1   51.091  ? 405 TSN A C8   1 
HETATM 5609 C  C9   . TSN F 5 .   ? -18.051 10.593  71.054 1   47.69   ? 405 TSN A C9   1 
HETATM 5610 C  C10  . TSN F 5 .   ? -17.776 11.36   69.869 1   44.973  ? 405 TSN A C10  1 
HETATM 5611 C  C11  . TSN F 5 .   ? -17.788 10.738  68.62  1   44.007  ? 405 TSN A C11  1 
HETATM 5612 C  C12  . TSN F 5 .   ? -17.575 11.214  67.311 1   49.102  ? 405 TSN A C12  1 
HETATM 5613 C  C13  . TSN F 5 .   ? -17.625 10.466  66.019 1   58.537  ? 405 TSN A C13  1 
HETATM 5614 C  C14  . TSN F 5 .   ? -18.205 9.676   73.334 1   57.515  ? 405 TSN A C14  1 
HETATM 5615 C  C15  . TSN F 5 .   ? -17.499 12.818  69.852 1   52.806  ? 405 TSN A C15  1 
HETATM 5616 C  C17  . TSN F 5 .   ? -14.79  15.355  78.167 1   53.995  ? 405 TSN A C17  1 
HETATM 5617 C  C16  . TSN F 5 .   ? -17.238 15.83   78.116 1   48.437  ? 405 TSN A C16  1 
HETATM 5618 H  HO1  . TSN F 5 .   ? -20.052 10.734  64.569 0   40.39   ? 405 TSN A HO1  1 
HETATM 5619 H  HN1  . TSN F 5 .   ? -18.025 11.921  64.843 1   63.417  ? 405 TSN A HN1  1 
HETATM 5620 H  H21  . TSN F 5 .   ? -14.482 12.067  74.67  1   51.793  ? 405 TSN A H21  1 
HETATM 5621 H  H31  . TSN F 5 .   ? -14.286 13.527  76.422 1   51.575  ? 405 TSN A H31  1 
HETATM 5622 H  H51  . TSN F 5 .   ? -18.187 14.473  76.063 1   52.169  ? 405 TSN A H51  1 
HETATM 5623 H  H61  . TSN F 5 .   ? -18.357 13.007  74.311 1   54.903  ? 405 TSN A H61  1 
HETATM 5624 H  H8   . TSN F 5 .   ? -18.575 11.619  72.742 1   52.768  ? 405 TSN A H8   1 
HETATM 5625 H  H9   . TSN F 5 .   ? -18.387 9.729   70.888 1   47.83   ? 405 TSN A H9   1 
HETATM 5626 H  H111 . TSN F 5 .   ? -17.974 9.814   68.652 1   45.423  ? 405 TSN A H111 1 
HETATM 5627 H  H121 . TSN F 5 .   ? -17.374 12.125  67.249 1   49.748  ? 405 TSN A H121 1 
HETATM 5628 H  H141 . TSN F 5 .   ? -19.041 9.288   73.025 1   55.245  ? 405 TSN A H141 1 
HETATM 5629 H  H142 . TSN F 5 .   ? -18.287 9.909   74.275 1   55.456  ? 405 TSN A H142 1 
HETATM 5630 H  H143 . TSN F 5 .   ? -17.488 9.031   73.222 1   55.324  ? 405 TSN A H143 1 
HETATM 5631 H  H151 . TSN F 5 .   ? -17.519 13.155  70.77  0   52.78   ? 405 TSN A H151 1 
HETATM 5632 H  H152 . TSN F 5 .   ? -18.147 13.272  69.323 0   52.78   ? 405 TSN A H152 1 
HETATM 5633 H  H153 . TSN F 5 .   ? -16.604 12.968  69.494 0   52.78   ? 405 TSN A H153 1 
HETATM 5634 H  H171 . TSN F 5 .   ? -14.116 14.802  77.714 0   53.42   ? 405 TSN A H171 1 
HETATM 5635 H  H172 . TSN F 5 .   ? -14.824 15.11   79.097 0   53.42   ? 405 TSN A H172 1 
HETATM 5636 H  H173 . TSN F 5 .   ? -14.577 16.278  78.056 0   53.42   ? 405 TSN A H173 1 
HETATM 5637 H  H161 . TSN F 5 .   ? -18.054 15.567  77.636 0   47.83   ? 405 TSN A H161 1 
HETATM 5638 H  H162 . TSN F 5 .   ? -17.091 16.768  78.009 0   47.83   ? 405 TSN A H162 1 
HETATM 5639 H  H163 . TSN F 5 .   ? -17.339 15.6    79.049 0   47.83   ? 405 TSN A H163 1 
HETATM 5640 C  C1   . GOL G 6 .   ? -13.157 16.663  69.738 1   104.818 ? 406 GOL A C1   1 
HETATM 5641 O  O1   . GOL G 6 .   ? -13.014 17.278  68.447 1   99.345  ? 406 GOL A O1   1 
HETATM 5642 C  C2   . GOL G 6 .   ? -14.607 16.386  70.135 1   109.72  ? 406 GOL A C2   1 
HETATM 5643 O  O2   . GOL G 6 .   ? -14.674 15.574  71.325 1   69.49   ? 406 GOL A O2   1 
HETATM 5644 C  C3   . GOL G 6 .   ? -15.425 17.675  70.249 1   109.355 ? 406 GOL A C3   1 
HETATM 5645 O  O3   . GOL G 6 .   ? -16.794 17.469  70.587 1   79.49   ? 406 GOL A O3   1 
HETATM 5646 H  H11  . GOL G 6 .   ? -12.75  17.248  70.418 1   104.215 ? 406 GOL A H11  1 
HETATM 5647 H  H12  . GOL G 6 .   ? -12.661 15.809  69.74  1   103.892 ? 406 GOL A H12  1 
HETATM 5648 H  HO1  . GOL G 6 .   ? -12.369 17.533  68.416 0   97.22   ? 406 GOL A HO1  1 
HETATM 5649 H  H2   . GOL G 6 .   ? -15.006 15.859  69.404 1   98.538  ? 406 GOL A H2   1 
HETATM 5650 H  HO2  . GOL G 6 .   ? -14.297 15.873  72.05  0   72.71   ? 406 GOL A HO2  1 
HETATM 5651 H  H31  . GOL G 6 .   ? -15.382 18.153  69.386 1   99.891  ? 406 GOL A H31  1 
HETATM 5652 H  H32  . GOL G 6 .   ? -15.021 18.248  70.925 1   101.748 ? 406 GOL A H32  1 
HETATM 5653 H  HO3  . GOL G 6 .   ? -17.304 17.532  71.408 0   92.89   ? 406 GOL A HO3  1 
HETATM 5654 C  C1   A GOL H 6 .   ? -13.522 6.695   65.669 0.5 55.177  ? 407 GOL A C1   1 
HETATM 5655 C  C1   B GOL H 6 .   ? -14.002 8.065   67.043 0.5 78.739  ? 407 GOL A C1   1 
HETATM 5656 O  O1   A GOL H 6 .   ? -12.91  6.532   64.388 0.5 59.047  ? 407 GOL A O1   1 
HETATM 5657 O  O1   B GOL H 6 .   ? -12.717 8.675   66.872 0.5 65.456  ? 407 GOL A O1   1 
HETATM 5658 C  C2   . GOL H 6 .   ? -14.665 7.714   65.724 1   65.478  ? 407 GOL A C2   1 
HETATM 5659 O  O2   . GOL H 6 .   ? -15.96  7.069   65.834 1   47.821  ? 407 GOL A O2   1 
HETATM 5660 C  C3   . GOL H 6 .   ? -14.71  8.893   64.74  1   68.359  ? 407 GOL A C3   1 
HETATM 5661 O  O3   . GOL H 6 .   ? -14.002 8.707   63.496 1   100.157 ? 407 GOL A O3   1 
HETATM 5662 H  H11  A GOL H 6 .   ? -12.826 6.973   66.314 0.5 58.174  ? 407 GOL A H11  1 
HETATM 5663 H  H11  B GOL H 6 .   ? -14.588 8.683   67.544 0.5 71.68   ? 407 GOL A H11  1 
HETATM 5664 H  H12  A GOL H 6 .   ? -13.868 5.822   65.964 0.5 57.786  ? 407 GOL A H12  1 
HETATM 5665 H  H12  B GOL H 6 .   ? -13.897 7.242   67.573 0.5 71.46   ? 407 GOL A H12  1 
HETATM 5666 H  HO1  A GOL H 6 .   ? -11.902 5.956   66.254 0   68.15   ? 407 GOL A HO1  1 
HETATM 5667 H  HO1  B GOL H 6 .   ? -12.064 7.949   67.859 0   84.76   ? 407 GOL A HO1  1 
HETATM 5668 H  H2   A GOL H 6 .   ? -14.538 8.152   66.6   0.5 60.259  ? 407 GOL A H2   1 
HETATM 5669 H  H2   B GOL H 6 .   ? -14.071 7.047   65.305 0.5 64.477  ? 407 GOL A H2   1 
HETATM 5670 H  HO2  . GOL H 6 .   ? -16.005 7.437   66.379 0   47.51   ? 407 GOL A HO2  1 
HETATM 5671 H  H31  . GOL H 6 .   ? -14.342 9.692   65.191 1   73.883  ? 407 GOL A H31  1 
HETATM 5672 H  H32  . GOL H 6 .   ? -15.652 9.082   64.527 1   73.775  ? 407 GOL A H32  1 
HETATM 5673 H  HO3  . GOL H 6 .   ? -14.034 9.485   62.851 0   93.03   ? 407 GOL A HO3  1 
HETATM 5674 O  O    . HOH I 7 .   ? -35.309 -7.688  59.476 1   45.844  ? 501 HOH A O    1 
HETATM 5675 O  O    . HOH I 7 .   ? 0.282   22.683  59.178 1   35.632  ? 502 HOH A O    1 
HETATM 5676 O  O    . HOH I 7 .   ? -37.906 13.634  49.763 1   48.537  ? 503 HOH A O    1 
HETATM 5677 O  O    . HOH I 7 .   ? -2.875  30.664  60.06  1   42.062  ? 504 HOH A O    1 
HETATM 5678 O  O    . HOH I 7 .   ? -9.567  21.503  43.739 1   53.498  ? 505 HOH A O    1 
HETATM 5679 O  O    . HOH I 7 .   ? -1.925  14.624  46.844 1   41.832  ? 506 HOH A O    1 
HETATM 5680 O  O    . HOH I 7 .   ? -33.453 -4.105  66.107 1   44.021  ? 507 HOH A O    1 
HETATM 5681 O  O    . HOH I 7 .   ? -12.152 -8.533  39.335 1   44.043  ? 508 HOH A O    1 
HETATM 5682 O  O    . HOH I 7 .   ? -28.273 -7.994  57.491 1   43.392  ? 509 HOH A O    1 
HETATM 5683 O  O    . HOH I 7 .   ? -5.03   23.335  50.398 1   46.499  ? 510 HOH A O    1 
HETATM 5684 O  O    . HOH I 7 .   ? -3.218  10.787  68.856 1   55.204  ? 511 HOH A O    1 
HETATM 5685 O  O    . HOH I 7 .   ? -4.345  -8.076  47.403 1   45.472  ? 512 HOH A O    1 
HETATM 5686 O  O    . HOH I 7 .   ? -21.207 -4.862  72.645 1   33.701  ? 513 HOH A O    1 
HETATM 5687 O  O    . HOH I 7 .   ? -24.365 -6.616  70.466 1   32.65   ? 514 HOH A O    1 
HETATM 5688 O  O    . HOH I 7 .   ? -37.06  -2.957  64.363 1   39.018  ? 515 HOH A O    1 
HETATM 5689 O  O    . HOH I 7 .   ? -22.429 3.26    61.591 1   29.907  ? 516 HOH A O    1 
HETATM 5690 O  O    . HOH I 7 .   ? 0.839   13.748  63.616 1   39.597  ? 517 HOH A O    1 
HETATM 5691 O  O    . HOH I 7 .   ? -39.913 -10.317 72.758 1   41.832  ? 518 HOH A O    1 
HETATM 5692 O  O    . HOH I 7 .   ? -29.959 15.614  58.961 1   38.67   ? 519 HOH A O    1 
HETATM 5693 O  O    . HOH I 7 .   ? -20.402 17.042  56.309 1   39.845  ? 520 HOH A O    1 
HETATM 5694 O  O    . HOH I 7 .   ? -34.616 7.554   73.289 1   34.21   ? 521 HOH A O    1 
HETATM 5695 O  O    . HOH I 7 .   ? -20.546 -10.194 56.468 1   42.39   ? 522 HOH A O    1 
HETATM 5696 O  O    . HOH I 7 .   ? -13.232 27.881  65.982 1   46.436  ? 523 HOH A O    1 
HETATM 5697 O  O    . HOH I 7 .   ? -11.771 16.946  58.97  1   30.086  ? 524 HOH A O    1 
HETATM 5698 O  O    . HOH I 7 .   ? -13.275 -4.111  67.91  1   32.847  ? 525 HOH A O    1 
HETATM 5699 O  O    . HOH I 7 .   ? -30.936 -11.848 71.389 1   41.528  ? 526 HOH A O    1 
HETATM 5700 O  O    . HOH I 7 .   ? -32.059 -7.083  64.561 1   33.285  ? 527 HOH A O    1 
HETATM 5701 O  O    . HOH I 7 .   ? -7.062  6.019   87.258 1   29.9    ? 528 HOH A O    1 
HETATM 5702 O  O    . HOH I 7 .   ? -15.532 12.436  55.962 1   42.869  ? 529 HOH A O    1 
HETATM 5703 O  O    . HOH I 7 .   ? -27.24  18.003  66.387 1   51.456  ? 530 HOH A O    1 
HETATM 5704 O  O    . HOH I 7 .   ? -10.826 16.824  56.557 1   32.941  ? 531 HOH A O    1 
HETATM 5705 O  O    . HOH I 7 .   ? -2.395  -2.224  53.48  1   40.783  ? 532 HOH A O    1 
HETATM 5706 O  O    . HOH I 7 .   ? -12.52  9.299   59.029 1   36.791  ? 533 HOH A O    1 
HETATM 5707 O  O    . HOH I 7 .   ? -19.655 18.874  57.896 1   39.685  ? 534 HOH A O    1 
HETATM 5708 O  O    . HOH I 7 .   ? -13.413 4.033   61.212 1   42.028  ? 535 HOH A O    1 
HETATM 5709 O  O    . HOH I 7 .   ? -15.876 23.476  47.684 1   39.843  ? 536 HOH A O    1 
HETATM 5710 O  O    . HOH I 7 .   ? -15.022 31.659  53.075 1   54.61   ? 537 HOH A O    1 
HETATM 5711 O  O    . HOH I 7 .   ? -32.280 12.927  72.765 1   30.46   ? 538 HOH A O    1 
HETATM 5712 O  O    . HOH I 7 .   ? -23.84  14.003  56.679 1   43.08   ? 539 HOH A O    1 
HETATM 5713 O  O    . HOH I 7 .   ? -6.694  7.554   53.265 1   30.989  ? 540 HOH A O    1 
HETATM 5714 O  O    . HOH I 7 .   ? -30.194 20.32   55.787 1   44.658  ? 541 HOH A O    1 
HETATM 5715 O  O    . HOH I 7 .   ? -27.032 21.118  62.629 1   41.453  ? 542 HOH A O    1 
HETATM 5716 O  O    . HOH I 7 .   ? -20.798 6.757   37.022 1   44.065  ? 543 HOH A O    1 
HETATM 5717 O  O    . HOH I 7 .   ? -0.128  -3.916  50.495 1   35.063  ? 544 HOH A O    1 
HETATM 5718 O  O    . HOH I 7 .   ? -34.037 -6.954  66.325 1   36.499  ? 545 HOH A O    1 
HETATM 5719 O  O    . HOH I 7 .   ? 0.993   17.456  57.296 1   43.453  ? 546 HOH A O    1 
HETATM 5720 O  O    . HOH I 7 .   ? -1.286  15.738  62.889 1   36.286  ? 547 HOH A O    1 
HETATM 5721 O  O    . HOH I 7 .   ? -32.858 3.072   73.832 1   40.705  ? 548 HOH A O    1 
HETATM 5722 O  O    . HOH I 7 .   ? -26.446 10.898  67.708 1   30.868  ? 549 HOH A O    1 
HETATM 5723 O  O    . HOH I 7 .   ? -8.379  7.921   85.879 1   30.271  ? 550 HOH A O    1 
HETATM 5724 O  O    . HOH I 7 .   ? -9.604  -6.769  62.816 1   32.436  ? 551 HOH A O    1 
HETATM 5725 O  O    . HOH I 7 .   ? -4.011  16.39   78.057 1   41.487  ? 552 HOH A O    1 
HETATM 5726 O  O    . HOH I 7 .   ? -36.188 15.679  60.386 1   40.363  ? 553 HOH A O    1 
HETATM 5727 O  O    . HOH I 7 .   ? -9.572  13.77   64.138 1   36.852  ? 554 HOH A O    1 
HETATM 5728 O  O    . HOH I 7 .   ? -9.069  16.888  44.772 1   45.452  ? 555 HOH A O    1 
HETATM 5729 O  O    . HOH I 7 .   ? -0.327  5.949   61.163 1   40.282  ? 556 HOH A O    1 
HETATM 5730 O  O    . HOH I 7 .   ? -15.871 17.629  43.779 1   39.923  ? 557 HOH A O    1 
HETATM 5731 O  O    . HOH I 7 .   ? -10.443 -13.967 49.725 1   41.544  ? 558 HOH A O    1 
HETATM 5732 O  O    . HOH I 7 .   ? -1.259  3.515   52.823 1   41.23   ? 559 HOH A O    1 
HETATM 5733 O  O    . HOH I 7 .   ? -2.557  -0.677  47.926 1   39.067  ? 560 HOH A O    1 
HETATM 5734 O  O    . HOH I 7 .   ? -2.627  6.362   47.655 1   36.018  ? 561 HOH A O    1 
HETATM 5735 O  O    . HOH I 7 .   ? -3.75   -2.847  64.392 1   47      ? 562 HOH A O    1 
HETATM 5736 O  O    . HOH I 7 .   ? -27.387 13.315  68.356 1   33.764  ? 563 HOH A O    1 
HETATM 5737 O  O    . HOH I 7 .   ? -28.255 26.295  54.099 1   42.496  ? 564 HOH A O    1 
HETATM 5738 O  O    . HOH I 7 .   ? -29.174 -9.972  62.023 1   39.333  ? 565 HOH A O    1 
HETATM 5739 O  O    . HOH I 7 .   ? -18.568 3.868   33.965 1   58.882  ? 566 HOH A O    1 
HETATM 5740 O  O    . HOH I 7 .   ? -20.095 -8.678  46.847 1   40.232  ? 567 HOH A O    1 
HETATM 5741 O  O    . HOH I 7 .   ? -22.753 1.12    68.24  1   31.359  ? 568 HOH A O    1 
HETATM 5742 O  O    . HOH I 7 .   ? -38.011 22.706  60.368 1   45.146  ? 569 HOH A O    1 
HETATM 5743 O  O    . HOH I 7 .   ? -47.828 5.352   67.304 1   51.791  ? 570 HOH A O    1 
HETATM 5744 O  O    . HOH I 7 .   ? -6.132  28.575  55.878 1   46.501  ? 571 HOH A O    1 
HETATM 5745 O  O    . HOH I 7 .   ? -20.914 25.802  44.366 1   45.245  ? 572 HOH A O    1 
HETATM 5746 O  O    . HOH I 7 .   ? -27.678 8.374   73.245 1   36.502  ? 573 HOH A O    1 
HETATM 5747 O  O    . HOH I 7 .   ? -33.356 0.165   47.273 1   44.468  ? 574 HOH A O    1 
HETATM 5748 O  O    . HOH I 7 .   ? -35.151 22.591  60.677 1   43.205  ? 575 HOH A O    1 
HETATM 5749 O  O    . HOH I 7 .   ? -0.436  14.701  68.489 1   43.822  ? 576 HOH A O    1 
HETATM 5750 O  O    . HOH I 7 .   ? -5.028  10.231  66.533 1   49.65   ? 577 HOH A O    1 
HETATM 5751 O  O    . HOH I 7 .   ? -37.522 -7.193  73.014 1   38.693  ? 578 HOH A O    1 
HETATM 5752 O  O    . HOH I 7 .   ? -31.794 -4.586  53.497 1   43.608  ? 579 HOH A O    1 
HETATM 5753 O  O    . HOH I 7 .   ? -21.37  -8.393  49.106 1   43.54   ? 580 HOH A O    1 
HETATM 5754 O  O    . HOH I 7 .   ? -2.107  -2.060  60.853 1   36.018  ? 581 HOH A O    1 
HETATM 5755 O  O    . HOH I 7 .   ? -19.687 -15.397 65.466 1   35.759  ? 582 HOH A O    1 
HETATM 5756 O  O    . HOH I 7 .   ? -17.786 -12.284 43.699 1   46.477  ? 583 HOH A O    1 
HETATM 5757 O  O    . HOH I 7 .   ? -32.959 21.442  54.24  1   41.178  ? 584 HOH A O    1 
HETATM 5758 O  O    . HOH I 7 .   ? -10.692 15.242  85.554 1   39.256  ? 585 HOH A O    1 
HETATM 5759 O  O    . HOH I 7 .   ? -13.418 7.823   76.627 1   37.946  ? 586 HOH A O    1 
HETATM 5760 O  O    . HOH I 7 .   ? -14.347 -2.935  70.305 1   29.602  ? 587 HOH A O    1 
HETATM 5761 O  O    . HOH I 7 .   ? -27.097 15.136  58.408 1   40.736  ? 588 HOH A O    1 
HETATM 5762 O  O    . HOH I 7 .   ? -30.424 -7.119  72.455 1   48.588  ? 589 HOH A O    1 
HETATM 5763 O  O    . HOH I 7 .   ? -16.748 -10.459 54.282 1   41.407  ? 590 HOH A O    1 
HETATM 5764 O  O    . HOH I 7 .   ? -33.737 17.057  69.664 1   46.573  ? 591 HOH A O    1 
HETATM 5765 O  O    . HOH I 7 .   ? -16.874 -9.084  56.556 1   38.811  ? 592 HOH A O    1 
HETATM 5766 O  O    . HOH I 7 .   ? -18.36  15.169  55.731 1   38.178  ? 593 HOH A O    1 
HETATM 5767 O  O    . HOH I 7 .   ? -11.232 12.568  40.218 1   46.791  ? 594 HOH A O    1 
HETATM 5768 O  O    . HOH I 7 .   ? -21.035 7.721   73.409 1   35.098  ? 595 HOH A O    1 
HETATM 5769 O  O    . HOH I 7 .   ? -5.593  0.609   40.764 1   41.183  ? 596 HOH A O    1 
HETATM 5770 O  O    . HOH I 7 .   ? -1.45   0.137   55.727 1   33.776  ? 597 HOH A O    1 
HETATM 5771 O  O    . HOH I 7 .   ? -36.853 17.438  67.178 1   43.709  ? 598 HOH A O    1 
HETATM 5772 O  O    . HOH I 7 .   ? -11.14  -0.524  69.709 1   44.319  ? 599 HOH A O    1 
HETATM 5773 O  O    . HOH I 7 .   ? -3.394  24.568  72.045 1   52.088  ? 600 HOH A O    1 
HETATM 5774 O  O    . HOH I 7 .   ? -0.633  6.38    49.643 1   35.559  ? 601 HOH A O    1 
HETATM 5775 O  O    . HOH I 7 .   ? -19.7   -15.852 62.448 1   40.554  ? 602 HOH A O    1 
HETATM 5776 O  O    . HOH I 7 .   ? -0.247  29.743  60.275 1   42.543  ? 603 HOH A O    1 
HETATM 5777 O  O    . HOH I 7 .   ? -32.698 5.663   73.04  1   34.911  ? 604 HOH A O    1 
HETATM 5778 O  O    . HOH I 7 .   ? -19.081 -12.698 56.364 1   42.35   ? 605 HOH A O    1 
HETATM 5779 O  O    . HOH I 7 .   ? -37.911 -12.688 69.4   1   42.252  ? 606 HOH A O    1 
HETATM 5780 O  O    . HOH I 7 .   ? -29.137 22.716  62.036 1   50.129  ? 607 HOH A O    1 
HETATM 5781 O  O    . HOH I 7 .   ? -13.533 35.451  58     1   44.057  ? 608 HOH A O    1 
HETATM 5782 O  O    . HOH I 7 .   ? -26.61  14.175  56.127 1   47.38   ? 609 HOH A O    1 
HETATM 5783 O  O    . HOH I 7 .   ? -14.922 7.306   76.643 1   41.358  ? 610 HOH A O    1 
HETATM 5784 O  O    . HOH I 7 .   ? -9.024  18.99   44.66  1   52.089  ? 611 HOH A O    1 
HETATM 5785 O  O    . HOH I 7 .   ? -23.633 6.065   73.65  1   36.667  ? 612 HOH A O    1 
HETATM 5786 O  O    . HOH I 7 .   ? -17.824 31.592  54.587 1   54.345  ? 613 HOH A O    1 
HETATM 5787 O  O    . HOH I 7 .   ? -19.634 30.598  52.775 1   51.928  ? 614 HOH A O    1 
HETATM 5788 O  O    . HOH I 7 .   ? -40.029 -12.641 71.48  1   41.979  ? 615 HOH A O    1 
HETATM 5789 O  O    . HOH I 7 .   ? -35.632 -6.919  57.191 1   51.972  ? 616 HOH A O    1 
HETATM 5790 O  O    . HOH I 7 .   ? -2.941  4.626   45.746 1   44.436  ? 617 HOH A O    1 
HETATM 5791 O  O    . HOH I 7 .   ? -2.996  31.47   56.988 1   48.556  ? 618 HOH A O    1 
HETATM 5792 O  O    . HOH I 7 .   ? -2.323  -3.182  46.064 1   56.253  ? 619 HOH A O    1 
# 
