data_9GLO
# 
_entry.id   9GLO 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GLO         pdb_00009glo 10.2210/pdb9glo/pdb 
WWPDB D_1292141259 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-05-07 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GLO 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB 'UFC1 wild type'   2Z6O unspecified 
PDB 'UFC1 Y110A&F121A' 7NVJ unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              reuvenw@ekmd.huji.ac.il 
_pdbx_contact_author.name_first         Reuven 
_pdbx_contact_author.name_last          Wiener 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-4219-550X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kumar, M.'    1 0000-0002-7083-5690 
'Banerjee, S.' 2 0009-0002-9409-6797 
'Wiener, R.'   3 0000-0002-4219-550X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                3912 
_citation.page_last                 3912 
_citation.title                     
'UFC1 reveals the multifactorial and plastic nature of oxyanion holes in E2 conjugating enzymes.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-58826-y 
_citation.pdbx_database_id_PubMed   40280917 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kumar, M.'       1 ?                   
primary 'Banerjee, S.'    2 ?                   
primary 'Cohen-Kfir, E.'  3 ?                   
primary 'Mitelberg, M.B.' 4 ?                   
primary 'Tiwari, S.'      5 ?                   
primary 'Isupov, M.N.'    6 0000-0001-6842-4289 
primary 'Dessau, M.'      7 0000-0002-1954-3625 
primary 'Wiener, R.'      8 0000-0002-4219-550X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Ubiquitin-fold modifier-conjugating enzyme 1' 19652.488 1   ? 'C116E, T106S' ? 
'This double mutant UFC1 is modified at T106 to Serine and C116 to glutamate' 
2 non-polymer syn GLYCEROL                                       92.094    3   ? ?              ? ? 
3 non-polymer syn 'SULFATE ION'                                  96.063    1   ? ?              ? ? 
4 water       nat water                                          18.015    118 ? ?              ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Ufm1-conjugating enzyme 1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GSMADEATRRVVSEIPVLKTNAGPRDRELWVQRLKEEYQSLIRYVENNKNADNDWFRLESNKEGTRWFGKCWYIHDLLKY
EFDIEFDIPITYPTTAPEIAVPELDGKSAKMYRGGKIELTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLIQKGV
IHHKEKCNQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GSMADEATRRVVSEIPVLKTNAGPRDRELWVQRLKEEYQSLIRYVENNKNADNDWFRLESNKEGTRWFGKCWYIHDLLKY
EFDIEFDIPITYPTTAPEIAVPELDGKSAKMYRGGKIELTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLIQKGV
IHHKEKCNQ
;
_entity_poly.pdbx_strand_id                 AAA 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 GLYCEROL      GOL 
3 'SULFATE ION' SO4 
4 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   SER n 
1 3   MET n 
1 4   ALA n 
1 5   ASP n 
1 6   GLU n 
1 7   ALA n 
1 8   THR n 
1 9   ARG n 
1 10  ARG n 
1 11  VAL n 
1 12  VAL n 
1 13  SER n 
1 14  GLU n 
1 15  ILE n 
1 16  PRO n 
1 17  VAL n 
1 18  LEU n 
1 19  LYS n 
1 20  THR n 
1 21  ASN n 
1 22  ALA n 
1 23  GLY n 
1 24  PRO n 
1 25  ARG n 
1 26  ASP n 
1 27  ARG n 
1 28  GLU n 
1 29  LEU n 
1 30  TRP n 
1 31  VAL n 
1 32  GLN n 
1 33  ARG n 
1 34  LEU n 
1 35  LYS n 
1 36  GLU n 
1 37  GLU n 
1 38  TYR n 
1 39  GLN n 
1 40  SER n 
1 41  LEU n 
1 42  ILE n 
1 43  ARG n 
1 44  TYR n 
1 45  VAL n 
1 46  GLU n 
1 47  ASN n 
1 48  ASN n 
1 49  LYS n 
1 50  ASN n 
1 51  ALA n 
1 52  ASP n 
1 53  ASN n 
1 54  ASP n 
1 55  TRP n 
1 56  PHE n 
1 57  ARG n 
1 58  LEU n 
1 59  GLU n 
1 60  SER n 
1 61  ASN n 
1 62  LYS n 
1 63  GLU n 
1 64  GLY n 
1 65  THR n 
1 66  ARG n 
1 67  TRP n 
1 68  PHE n 
1 69  GLY n 
1 70  LYS n 
1 71  CYS n 
1 72  TRP n 
1 73  TYR n 
1 74  ILE n 
1 75  HIS n 
1 76  ASP n 
1 77  LEU n 
1 78  LEU n 
1 79  LYS n 
1 80  TYR n 
1 81  GLU n 
1 82  PHE n 
1 83  ASP n 
1 84  ILE n 
1 85  GLU n 
1 86  PHE n 
1 87  ASP n 
1 88  ILE n 
1 89  PRO n 
1 90  ILE n 
1 91  THR n 
1 92  TYR n 
1 93  PRO n 
1 94  THR n 
1 95  THR n 
1 96  ALA n 
1 97  PRO n 
1 98  GLU n 
1 99  ILE n 
1 100 ALA n 
1 101 VAL n 
1 102 PRO n 
1 103 GLU n 
1 104 LEU n 
1 105 ASP n 
1 106 GLY n 
1 107 LYS n 
1 108 SER n 
1 109 ALA n 
1 110 LYS n 
1 111 MET n 
1 112 TYR n 
1 113 ARG n 
1 114 GLY n 
1 115 GLY n 
1 116 LYS n 
1 117 ILE n 
1 118 GLU n 
1 119 LEU n 
1 120 THR n 
1 121 ASP n 
1 122 HIS n 
1 123 PHE n 
1 124 LYS n 
1 125 PRO n 
1 126 LEU n 
1 127 TRP n 
1 128 ALA n 
1 129 ARG n 
1 130 ASN n 
1 131 VAL n 
1 132 PRO n 
1 133 LYS n 
1 134 PHE n 
1 135 GLY n 
1 136 LEU n 
1 137 ALA n 
1 138 HIS n 
1 139 LEU n 
1 140 MET n 
1 141 ALA n 
1 142 LEU n 
1 143 GLY n 
1 144 LEU n 
1 145 GLY n 
1 146 PRO n 
1 147 TRP n 
1 148 LEU n 
1 149 ALA n 
1 150 VAL n 
1 151 GLU n 
1 152 ILE n 
1 153 PRO n 
1 154 ASP n 
1 155 LEU n 
1 156 ILE n 
1 157 GLN n 
1 158 LYS n 
1 159 GLY n 
1 160 VAL n 
1 161 ILE n 
1 162 HIS n 
1 163 HIS n 
1 164 LYS n 
1 165 GLU n 
1 166 LYS n 
1 167 CYS n 
1 168 ASN n 
1 169 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   169 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'UFC1, CGI-126, HSPC155' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?                               'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ?                               'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?                               'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                               'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ?                               'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ?                               'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                               'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ?                               'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL        'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE       ?                               'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ?                               'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ?                               'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ?                               'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ?                               'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ?                               'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ?                               'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ?                               'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ?                               'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ?                               'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ?                               'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?                               'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ?                               'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ?                               'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -1  ?   ?   ?   AAA . n 
A 1 2   SER 2   0   0   SER SER AAA . n 
A 1 3   MET 3   1   1   MET MET AAA . n 
A 1 4   ALA 4   2   2   ALA ALA AAA . n 
A 1 5   ASP 5   3   3   ASP ASP AAA . n 
A 1 6   GLU 6   4   4   GLU GLU AAA . n 
A 1 7   ALA 7   5   5   ALA ALA AAA . n 
A 1 8   THR 8   6   6   THR THR AAA . n 
A 1 9   ARG 9   7   7   ARG ARG AAA . n 
A 1 10  ARG 10  8   8   ARG ARG AAA . n 
A 1 11  VAL 11  9   9   VAL VAL AAA . n 
A 1 12  VAL 12  10  10  VAL VAL AAA . n 
A 1 13  SER 13  11  11  SER SER AAA . n 
A 1 14  GLU 14  12  12  GLU GLU AAA . n 
A 1 15  ILE 15  13  13  ILE ILE AAA . n 
A 1 16  PRO 16  14  14  PRO PRO AAA . n 
A 1 17  VAL 17  15  15  VAL VAL AAA . n 
A 1 18  LEU 18  16  16  LEU LEU AAA . n 
A 1 19  LYS 19  17  17  LYS LYS AAA . n 
A 1 20  THR 20  18  18  THR THR AAA . n 
A 1 21  ASN 21  19  19  ASN ASN AAA . n 
A 1 22  ALA 22  20  20  ALA ALA AAA . n 
A 1 23  GLY 23  21  21  GLY GLY AAA . n 
A 1 24  PRO 24  22  22  PRO PRO AAA . n 
A 1 25  ARG 25  23  23  ARG ARG AAA . n 
A 1 26  ASP 26  24  24  ASP ASP AAA . n 
A 1 27  ARG 27  25  25  ARG ARG AAA . n 
A 1 28  GLU 28  26  26  GLU GLU AAA . n 
A 1 29  LEU 29  27  27  LEU LEU AAA . n 
A 1 30  TRP 30  28  28  TRP TRP AAA . n 
A 1 31  VAL 31  29  29  VAL VAL AAA . n 
A 1 32  GLN 32  30  30  GLN GLN AAA . n 
A 1 33  ARG 33  31  31  ARG ARG AAA . n 
A 1 34  LEU 34  32  32  LEU LEU AAA . n 
A 1 35  LYS 35  33  33  LYS LYS AAA . n 
A 1 36  GLU 36  34  34  GLU GLU AAA . n 
A 1 37  GLU 37  35  35  GLU GLU AAA . n 
A 1 38  TYR 38  36  36  TYR TYR AAA . n 
A 1 39  GLN 39  37  37  GLN GLN AAA . n 
A 1 40  SER 40  38  38  SER SER AAA . n 
A 1 41  LEU 41  39  39  LEU LEU AAA . n 
A 1 42  ILE 42  40  40  ILE ILE AAA . n 
A 1 43  ARG 43  41  41  ARG ARG AAA . n 
A 1 44  TYR 44  42  42  TYR TYR AAA . n 
A 1 45  VAL 45  43  43  VAL VAL AAA . n 
A 1 46  GLU 46  44  44  GLU GLU AAA . n 
A 1 47  ASN 47  45  45  ASN ASN AAA . n 
A 1 48  ASN 48  46  46  ASN ASN AAA . n 
A 1 49  LYS 49  47  47  LYS LYS AAA . n 
A 1 50  ASN 50  48  48  ASN ASN AAA . n 
A 1 51  ALA 51  49  49  ALA ALA AAA . n 
A 1 52  ASP 52  50  50  ASP ASP AAA . n 
A 1 53  ASN 53  51  51  ASN ASN AAA . n 
A 1 54  ASP 54  52  52  ASP ASP AAA . n 
A 1 55  TRP 55  53  53  TRP TRP AAA . n 
A 1 56  PHE 56  54  54  PHE PHE AAA . n 
A 1 57  ARG 57  55  55  ARG ARG AAA . n 
A 1 58  LEU 58  56  56  LEU LEU AAA . n 
A 1 59  GLU 59  57  57  GLU GLU AAA . n 
A 1 60  SER 60  58  58  SER SER AAA . n 
A 1 61  ASN 61  59  59  ASN ASN AAA . n 
A 1 62  LYS 62  60  60  LYS LYS AAA . n 
A 1 63  GLU 63  61  61  GLU GLU AAA . n 
A 1 64  GLY 64  62  62  GLY GLY AAA . n 
A 1 65  THR 65  63  63  THR THR AAA . n 
A 1 66  ARG 66  64  64  ARG ARG AAA . n 
A 1 67  TRP 67  65  65  TRP TRP AAA . n 
A 1 68  PHE 68  66  66  PHE PHE AAA . n 
A 1 69  GLY 69  67  67  GLY GLY AAA . n 
A 1 70  LYS 70  68  68  LYS LYS AAA . n 
A 1 71  CYS 71  69  69  CYS CYS AAA . n 
A 1 72  TRP 72  70  70  TRP TRP AAA . n 
A 1 73  TYR 73  71  71  TYR TYR AAA . n 
A 1 74  ILE 74  72  72  ILE ILE AAA . n 
A 1 75  HIS 75  73  73  HIS HIS AAA . n 
A 1 76  ASP 76  74  74  ASP ASP AAA . n 
A 1 77  LEU 77  75  75  LEU LEU AAA . n 
A 1 78  LEU 78  76  76  LEU LEU AAA . n 
A 1 79  LYS 79  77  77  LYS LYS AAA . n 
A 1 80  TYR 80  78  78  TYR TYR AAA . n 
A 1 81  GLU 81  79  79  GLU GLU AAA . n 
A 1 82  PHE 82  80  80  PHE PHE AAA . n 
A 1 83  ASP 83  81  81  ASP ASP AAA . n 
A 1 84  ILE 84  82  82  ILE ILE AAA . n 
A 1 85  GLU 85  83  83  GLU GLU AAA . n 
A 1 86  PHE 86  84  84  PHE PHE AAA . n 
A 1 87  ASP 87  85  85  ASP ASP AAA . n 
A 1 88  ILE 88  86  86  ILE ILE AAA . n 
A 1 89  PRO 89  87  87  PRO PRO AAA . n 
A 1 90  ILE 90  88  88  ILE ILE AAA . n 
A 1 91  THR 91  89  89  THR THR AAA . n 
A 1 92  TYR 92  90  90  TYR TYR AAA . n 
A 1 93  PRO 93  91  91  PRO PRO AAA . n 
A 1 94  THR 94  92  92  THR THR AAA . n 
A 1 95  THR 95  93  93  THR THR AAA . n 
A 1 96  ALA 96  94  94  ALA ALA AAA . n 
A 1 97  PRO 97  95  95  PRO PRO AAA . n 
A 1 98  GLU 98  96  96  GLU GLU AAA . n 
A 1 99  ILE 99  97  97  ILE ILE AAA . n 
A 1 100 ALA 100 98  98  ALA ALA AAA . n 
A 1 101 VAL 101 99  99  VAL VAL AAA . n 
A 1 102 PRO 102 100 100 PRO PRO AAA . n 
A 1 103 GLU 103 101 101 GLU GLU AAA . n 
A 1 104 LEU 104 102 102 LEU LEU AAA . n 
A 1 105 ASP 105 103 103 ASP ASP AAA . n 
A 1 106 GLY 106 104 104 GLY GLY AAA . n 
A 1 107 LYS 107 105 105 LYS LYS AAA . n 
A 1 108 SER 108 106 106 SER SER AAA . n 
A 1 109 ALA 109 107 107 ALA ALA AAA . n 
A 1 110 LYS 110 108 108 LYS LYS AAA . n 
A 1 111 MET 111 109 109 MET MET AAA . n 
A 1 112 TYR 112 110 110 TYR TYR AAA . n 
A 1 113 ARG 113 111 111 ARG ARG AAA . n 
A 1 114 GLY 114 112 112 GLY GLY AAA . n 
A 1 115 GLY 115 113 113 GLY GLY AAA . n 
A 1 116 LYS 116 114 114 LYS LYS AAA . n 
A 1 117 ILE 117 115 115 ILE ILE AAA . n 
A 1 118 GLU 118 116 116 GLU GLU AAA . n 
A 1 119 LEU 119 117 117 LEU LEU AAA . n 
A 1 120 THR 120 118 118 THR THR AAA . n 
A 1 121 ASP 121 119 119 ASP ASP AAA . n 
A 1 122 HIS 122 120 120 HIS HIS AAA . n 
A 1 123 PHE 123 121 121 PHE PHE AAA . n 
A 1 124 LYS 124 122 122 LYS LYS AAA . n 
A 1 125 PRO 125 123 123 PRO PRO AAA . n 
A 1 126 LEU 126 124 124 LEU LEU AAA . n 
A 1 127 TRP 127 125 125 TRP TRP AAA . n 
A 1 128 ALA 128 126 126 ALA ALA AAA . n 
A 1 129 ARG 129 127 127 ARG ARG AAA . n 
A 1 130 ASN 130 128 128 ASN ASN AAA . n 
A 1 131 VAL 131 129 129 VAL VAL AAA . n 
A 1 132 PRO 132 130 130 PRO PRO AAA . n 
A 1 133 LYS 133 131 131 LYS LYS AAA . n 
A 1 134 PHE 134 132 132 PHE PHE AAA . n 
A 1 135 GLY 135 133 133 GLY GLY AAA . n 
A 1 136 LEU 136 134 134 LEU LEU AAA . n 
A 1 137 ALA 137 135 135 ALA ALA AAA . n 
A 1 138 HIS 138 136 136 HIS HIS AAA . n 
A 1 139 LEU 139 137 137 LEU LEU AAA . n 
A 1 140 MET 140 138 138 MET MET AAA . n 
A 1 141 ALA 141 139 139 ALA ALA AAA . n 
A 1 142 LEU 142 140 140 LEU LEU AAA . n 
A 1 143 GLY 143 141 141 GLY GLY AAA . n 
A 1 144 LEU 144 142 142 LEU LEU AAA . n 
A 1 145 GLY 145 143 143 GLY GLY AAA . n 
A 1 146 PRO 146 144 144 PRO PRO AAA . n 
A 1 147 TRP 147 145 145 TRP TRP AAA . n 
A 1 148 LEU 148 146 146 LEU LEU AAA . n 
A 1 149 ALA 149 147 147 ALA ALA AAA . n 
A 1 150 VAL 150 148 148 VAL VAL AAA . n 
A 1 151 GLU 151 149 149 GLU GLU AAA . n 
A 1 152 ILE 152 150 150 ILE ILE AAA . n 
A 1 153 PRO 153 151 151 PRO PRO AAA . n 
A 1 154 ASP 154 152 152 ASP ASP AAA . n 
A 1 155 LEU 155 153 153 LEU LEU AAA . n 
A 1 156 ILE 156 154 154 ILE ILE AAA . n 
A 1 157 GLN 157 155 155 GLN GLN AAA . n 
A 1 158 LYS 158 156 156 LYS LYS AAA . n 
A 1 159 GLY 159 157 157 GLY GLY AAA . n 
A 1 160 VAL 160 158 158 VAL VAL AAA . n 
A 1 161 ILE 161 159 159 ILE ILE AAA . n 
A 1 162 HIS 162 160 160 HIS HIS AAA . n 
A 1 163 HIS 163 161 161 HIS HIS AAA . n 
A 1 164 LYS 164 162 ?   ?   ?   AAA . n 
A 1 165 GLU 165 163 ?   ?   ?   AAA . n 
A 1 166 LYS 166 164 ?   ?   ?   AAA . n 
A 1 167 CYS 167 165 ?   ?   ?   AAA . n 
A 1 168 ASN 168 166 ?   ?   ?   AAA . n 
A 1 169 GLN 169 167 ?   ?   ?   AAA . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 GOL 1   201 201 GOL GOL AAA . 
C 2 GOL 1   202 202 GOL GOL AAA . 
D 2 GOL 1   203 203 GOL GOL AAA . 
E 3 SO4 1   204 204 SO4 SO4 AAA . 
F 4 HOH 1   301 79  HOH HOH AAA . 
F 4 HOH 2   302 93  HOH HOH AAA . 
F 4 HOH 3   303 43  HOH HOH AAA . 
F 4 HOH 4   304 91  HOH HOH AAA . 
F 4 HOH 5   305 66  HOH HOH AAA . 
F 4 HOH 6   306 15  HOH HOH AAA . 
F 4 HOH 7   307 22  HOH HOH AAA . 
F 4 HOH 8   308 83  HOH HOH AAA . 
F 4 HOH 9   309 20  HOH HOH AAA . 
F 4 HOH 10  310 80  HOH HOH AAA . 
F 4 HOH 11  311 92  HOH HOH AAA . 
F 4 HOH 12  312 85  HOH HOH AAA . 
F 4 HOH 13  313 13  HOH HOH AAA . 
F 4 HOH 14  314 45  HOH HOH AAA . 
F 4 HOH 15  315 39  HOH HOH AAA . 
F 4 HOH 16  316 52  HOH HOH AAA . 
F 4 HOH 17  317 96  HOH HOH AAA . 
F 4 HOH 18  318 98  HOH HOH AAA . 
F 4 HOH 19  319 94  HOH HOH AAA . 
F 4 HOH 20  320 99  HOH HOH AAA . 
F 4 HOH 21  321 31  HOH HOH AAA . 
F 4 HOH 22  322 81  HOH HOH AAA . 
F 4 HOH 23  323 64  HOH HOH AAA . 
F 4 HOH 24  324 84  HOH HOH AAA . 
F 4 HOH 25  325 61  HOH HOH AAA . 
F 4 HOH 26  326 14  HOH HOH AAA . 
F 4 HOH 27  327 26  HOH HOH AAA . 
F 4 HOH 28  328 115 HOH HOH AAA . 
F 4 HOH 29  329 109 HOH HOH AAA . 
F 4 HOH 30  330 90  HOH HOH AAA . 
F 4 HOH 31  331 58  HOH HOH AAA . 
F 4 HOH 32  332 18  HOH HOH AAA . 
F 4 HOH 33  333 9   HOH HOH AAA . 
F 4 HOH 34  334 37  HOH HOH AAA . 
F 4 HOH 35  335 67  HOH HOH AAA . 
F 4 HOH 36  336 6   HOH HOH AAA . 
F 4 HOH 37  337 28  HOH HOH AAA . 
F 4 HOH 38  338 10  HOH HOH AAA . 
F 4 HOH 39  339 108 HOH HOH AAA . 
F 4 HOH 40  340 3   HOH HOH AAA . 
F 4 HOH 41  341 23  HOH HOH AAA . 
F 4 HOH 42  342 8   HOH HOH AAA . 
F 4 HOH 43  343 65  HOH HOH AAA . 
F 4 HOH 44  344 102 HOH HOH AAA . 
F 4 HOH 45  345 89  HOH HOH AAA . 
F 4 HOH 46  346 5   HOH HOH AAA . 
F 4 HOH 47  347 11  HOH HOH AAA . 
F 4 HOH 48  348 24  HOH HOH AAA . 
F 4 HOH 49  349 60  HOH HOH AAA . 
F 4 HOH 50  350 16  HOH HOH AAA . 
F 4 HOH 51  351 49  HOH HOH AAA . 
F 4 HOH 52  352 75  HOH HOH AAA . 
F 4 HOH 53  353 40  HOH HOH AAA . 
F 4 HOH 54  354 25  HOH HOH AAA . 
F 4 HOH 55  355 17  HOH HOH AAA . 
F 4 HOH 56  356 100 HOH HOH AAA . 
F 4 HOH 57  357 87  HOH HOH AAA . 
F 4 HOH 58  358 56  HOH HOH AAA . 
F 4 HOH 59  359 12  HOH HOH AAA . 
F 4 HOH 60  360 27  HOH HOH AAA . 
F 4 HOH 61  361 32  HOH HOH AAA . 
F 4 HOH 62  362 77  HOH HOH AAA . 
F 4 HOH 63  363 69  HOH HOH AAA . 
F 4 HOH 64  364 19  HOH HOH AAA . 
F 4 HOH 65  365 97  HOH HOH AAA . 
F 4 HOH 66  366 72  HOH HOH AAA . 
F 4 HOH 67  367 1   HOH HOH AAA . 
F 4 HOH 68  368 38  HOH HOH AAA . 
F 4 HOH 69  369 54  HOH HOH AAA . 
F 4 HOH 70  370 48  HOH HOH AAA . 
F 4 HOH 71  371 55  HOH HOH AAA . 
F 4 HOH 72  372 4   HOH HOH AAA . 
F 4 HOH 73  373 53  HOH HOH AAA . 
F 4 HOH 74  374 35  HOH HOH AAA . 
F 4 HOH 75  375 57  HOH HOH AAA . 
F 4 HOH 76  376 36  HOH HOH AAA . 
F 4 HOH 77  377 59  HOH HOH AAA . 
F 4 HOH 78  378 68  HOH HOH AAA . 
F 4 HOH 79  379 101 HOH HOH AAA . 
F 4 HOH 80  380 21  HOH HOH AAA . 
F 4 HOH 81  381 34  HOH HOH AAA . 
F 4 HOH 82  382 50  HOH HOH AAA . 
F 4 HOH 83  383 7   HOH HOH AAA . 
F 4 HOH 84  384 71  HOH HOH AAA . 
F 4 HOH 85  385 62  HOH HOH AAA . 
F 4 HOH 86  386 30  HOH HOH AAA . 
F 4 HOH 87  387 42  HOH HOH AAA . 
F 4 HOH 88  388 63  HOH HOH AAA . 
F 4 HOH 89  389 74  HOH HOH AAA . 
F 4 HOH 90  390 110 HOH HOH AAA . 
F 4 HOH 91  391 70  HOH HOH AAA . 
F 4 HOH 92  392 73  HOH HOH AAA . 
F 4 HOH 93  393 2   HOH HOH AAA . 
F 4 HOH 94  394 46  HOH HOH AAA . 
F 4 HOH 95  395 51  HOH HOH AAA . 
F 4 HOH 96  396 33  HOH HOH AAA . 
F 4 HOH 97  397 111 HOH HOH AAA . 
F 4 HOH 98  398 47  HOH HOH AAA . 
F 4 HOH 99  399 78  HOH HOH AAA . 
F 4 HOH 100 400 44  HOH HOH AAA . 
F 4 HOH 101 401 86  HOH HOH AAA . 
F 4 HOH 102 402 76  HOH HOH AAA . 
F 4 HOH 103 403 95  HOH HOH AAA . 
F 4 HOH 104 404 116 HOH HOH AAA . 
F 4 HOH 105 405 29  HOH HOH AAA . 
F 4 HOH 106 406 103 HOH HOH AAA . 
F 4 HOH 107 407 119 HOH HOH AAA . 
F 4 HOH 108 408 117 HOH HOH AAA . 
F 4 HOH 109 409 107 HOH HOH AAA . 
F 4 HOH 110 410 88  HOH HOH AAA . 
F 4 HOH 111 411 113 HOH HOH AAA . 
F 4 HOH 112 412 104 HOH HOH AAA . 
F 4 HOH 113 413 106 HOH HOH AAA . 
F 4 HOH 114 414 114 HOH HOH AAA . 
F 4 HOH 115 415 118 HOH HOH AAA . 
F 4 HOH 116 416 82  HOH HOH AAA . 
F 4 HOH 117 417 105 HOH HOH AAA . 
F 4 HOH 118 418 112 HOH HOH AAA . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 AAA ARG 25  ? NE  ? A ARG 27  NE  
2  1 Y 1 AAA ARG 25  ? CZ  ? A ARG 27  CZ  
3  1 Y 1 AAA ARG 25  ? NH1 ? A ARG 27  NH1 
4  1 Y 1 AAA ARG 25  ? NH2 ? A ARG 27  NH2 
5  1 Y 1 AAA LYS 60  ? CD  ? A LYS 62  CD  
6  1 Y 1 AAA LYS 60  ? CE  ? A LYS 62  CE  
7  1 Y 1 AAA LYS 60  ? NZ  ? A LYS 62  NZ  
8  1 Y 1 AAA GLU 61  ? OE2 ? A GLU 63  OE2 
9  1 Y 1 AAA ARG 64  ? CD  ? A ARG 66  CD  
10 1 Y 1 AAA ARG 64  ? NE  ? A ARG 66  NE  
11 1 Y 1 AAA ARG 64  ? CZ  ? A ARG 66  CZ  
12 1 Y 1 AAA ARG 64  ? NH1 ? A ARG 66  NH1 
13 1 Y 1 AAA ARG 64  ? NH2 ? A ARG 66  NH2 
14 1 Y 1 AAA LYS 77  ? NZ  ? A LYS 79  NZ  
15 1 Y 1 AAA ASP 85  ? OD1 ? A ASP 87  OD1 
16 1 Y 1 AAA GLN 155 ? NE2 ? A GLN 157 NE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0267           1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .                  2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .                  3 
? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot     ? ? ? 'Wincoot 0.9.6 EL' 4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GLO 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     46.802 
_cell.length_a_esd                 ? 
_cell.length_b                     46.802 
_cell.length_b_esd                 ? 
_cell.length_c                     144.376 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GLO 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                92 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 41 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GLO 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.01 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          38.85 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              5.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M Bis-Tris, pH 5.5, 2 M ammonium sulfate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     298 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-01-19 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.87313 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE ID23-2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.87313 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ID23-2 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          17.17 
_reflns.entry_id                                       9GLO 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.53 
_reflns.d_resolution_low                               39.27 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     25209 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.99 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          16.90 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.02536 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.53 
_reflns_shell.d_res_low                                     1.585 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           4.76 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2454 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               2.0 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.1641 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.963 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.193 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            -0.000 
_refine.aniso_B[2][2]                            0.193 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            -0.385 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               17.152 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.965 
_refine.correlation_coeff_Fo_to_Fc_free          0.950 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9GLO 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.530 
_refine.ls_d_res_low                             39.27 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     25209 
_refine.ls_number_reflns_R_free                  1250 
_refine.ls_number_reflns_R_work                  23959 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.996 
_refine.ls_percent_reflns_R_free                 4.959 
_refine.ls_R_factor_all                          0.178 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2077 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1768 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.078 
_refine.pdbx_overall_ESU_R_Free                  0.080 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             1.283 
_refine.overall_SU_ML                            0.048 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        1316 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         23 
_refine_hist.number_atoms_solvent             118 
_refine_hist.number_atoms_total               1457 
_refine_hist.d_res_high                       1.530 
_refine_hist.d_res_low                        39.27 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.013  0.013  1380 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.015  1290 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 2.027  1.642  1870 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 1.541  1.580  2979 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.257  5.000  163  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 29.441 22.254 71   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 12.385 15.000 228  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 11.133 15.000 8    ? r_dihedral_angle_4_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.107  0.200  171  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.012  0.020  1513 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  311  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.224  0.200  265  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.194  0.200  1144 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.178  0.200  659  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.088  0.200  560  ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.129  0.200  61   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.292  0.200  12   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.270  0.200  39   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.208  0.200  18   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 1.523  1.547  652  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 1.504  1.544  651  ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 2.215  2.318  815  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 2.219  2.321  816  ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 3.030  1.898  728  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 3.010  1.887  725  ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 4.241  2.703  1055 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 4.213  2.686  1050 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 5.226  18.992 1552 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.183  18.867 1543 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.530 1.570 . . 101 1719 100.0000 . . . . 0.205 . . . . . . . . . . . 0.253 
'X-RAY DIFFRACTION' 1.570 1.613 . . 78  1700 100.0000 . . . . 0.188 . . . . . . . . . . . 0.265 
'X-RAY DIFFRACTION' 1.613 1.659 . . 83  1642 100.0000 . . . . 0.197 . . . . . . . . . . . 0.259 
'X-RAY DIFFRACTION' 1.659 1.710 . . 77  1577 100.0000 . . . . 0.192 . . . . . . . . . . . 0.198 
'X-RAY DIFFRACTION' 1.710 1.766 . . 75  1567 100.0000 . . . . 0.185 . . . . . . . . . . . 0.206 
'X-RAY DIFFRACTION' 1.766 1.828 . . 73  1516 100.0000 . . . . 0.179 . . . . . . . . . . . 0.227 
'X-RAY DIFFRACTION' 1.828 1.897 . . 69  1468 100.0000 . . . . 0.171 . . . . . . . . . . . 0.220 
'X-RAY DIFFRACTION' 1.897 1.974 . . 76  1383 100.0000 . . . . 0.189 . . . . . . . . . . . 0.222 
'X-RAY DIFFRACTION' 1.974 2.062 . . 59  1358 100.0000 . . . . 0.178 . . . . . . . . . . . 0.167 
'X-RAY DIFFRACTION' 2.062 2.162 . . 70  1283 100.0000 . . . . 0.176 . . . . . . . . . . . 0.224 
'X-RAY DIFFRACTION' 2.162 2.279 . . 65  1236 100.0000 . . . . 0.165 . . . . . . . . . . . 0.162 
'X-RAY DIFFRACTION' 2.279 2.417 . . 48  1189 100.0000 . . . . 0.180 . . . . . . . . . . . 0.199 
'X-RAY DIFFRACTION' 2.417 2.583 . . 66  1104 99.9146  . . . . 0.164 . . . . . . . . . . . 0.216 
'X-RAY DIFFRACTION' 2.583 2.790 . . 58  1035 100.0000 . . . . 0.171 . . . . . . . . . . . 0.211 
'X-RAY DIFFRACTION' 2.790 3.055 . . 72  934  100.0000 . . . . 0.176 . . . . . . . . . . . 0.187 
'X-RAY DIFFRACTION' 3.055 3.413 . . 50  876  100.0000 . . . . 0.177 . . . . . . . . . . . 0.197 
'X-RAY DIFFRACTION' 3.413 3.937 . . 44  791  100.0000 . . . . 0.155 . . . . . . . . . . . 0.168 
'X-RAY DIFFRACTION' 3.937 4.813 . . 36  686  100.0000 . . . . 0.153 . . . . . . . . . . . 0.177 
'X-RAY DIFFRACTION' 4.813 6.767 . . 30  544  100.0000 . . . . 0.206 . . . . . . . . . . . 0.269 
# 
_struct.entry_id                     9GLO 
_struct.title                        'Crystal Structure of UFC1 C116E&T106S' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GLO 
_struct_keywords.text            
'UFM1 conjugating enzyme1, UBC core domain containing protein, Brain development, Infantile encephalopathy, LIGASE' 
_struct_keywords.pdbx_keywords   LIGASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    UFC1_HUMAN 
_struct_ref.pdbx_db_accession          Q9Y3C8 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MADEATRRVVSEIPVLKTNAGPRDRELWVQRLKEEYQSLIRYVENNKNADNDWFRLESNKEGTRWFGKCWYIHDLLKYEF
DIEFDIPITYPTTAPEIAVPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLIQKGVIQ
HKEKCNQ
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9GLO 
_struct_ref_seq.pdbx_strand_id                AAA 
_struct_ref_seq.seq_align_beg                 3 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 169 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q9Y3C8 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  167 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       167 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9GLO GLY AAA 1   ? UNP Q9Y3C8 ?   ?   'expression tag'      -1  1 
1 9GLO SER AAA 2   ? UNP Q9Y3C8 ?   ?   'expression tag'      0   2 
1 9GLO SER AAA 108 ? UNP Q9Y3C8 THR 106 'engineered mutation' 106 3 
1 9GLO GLU AAA 118 ? UNP Q9Y3C8 CYS 116 'engineered mutation' 116 4 
1 9GLO HIS AAA 162 ? UNP Q9Y3C8 GLN 160 conflict              160 5 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 SER A 2   ? SER A 13  ? SER AAA 0   SER AAA 11  1 ? 12 
HELX_P HELX_P2 AA2 ARG A 27  ? ALA A 51  ? ARG AAA 25  ALA AAA 49  1 ? 25 
HELX_P HELX_P3 AA3 VAL A 101 ? ASP A 105 ? VAL AAA 99  ASP AAA 103 5 ? 5  
HELX_P HELX_P4 AA4 ARG A 113 ? GLY A 115 ? ARG AAA 111 GLY AAA 113 5 ? 3  
HELX_P HELX_P5 AA5 HIS A 122 ? VAL A 131 ? HIS AAA 120 VAL AAA 129 1 ? 10 
HELX_P HELX_P6 AA6 GLY A 135 ? GLY A 143 ? GLY AAA 133 GLY AAA 141 1 ? 9  
HELX_P HELX_P7 AA7 GLY A 143 ? LYS A 158 ? GLY AAA 141 LYS AAA 156 1 ? 16 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TYR 92  A . ? TYR 90  AAA PRO 93  A ? PRO 91  AAA 1 4.68  
2 VAL 131 A . ? VAL 129 AAA PRO 132 A ? PRO 130 AAA 1 -1.70 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA2 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 56  ? SER A 60  ? PHE AAA 54  SER AAA 58  
AA1 2 ARG A 66  ? HIS A 75  ? ARG AAA 64  HIS AAA 73  
AA1 3 LEU A 78  ? ASP A 87  ? LEU AAA 76  ASP AAA 85  
AA2 1 MET A 111 ? TYR A 112 ? MET AAA 109 TYR AAA 110 
AA2 2 LYS A 116 ? ILE A 117 ? LYS AAA 114 ILE AAA 115 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLU A 59  ? N GLU AAA 57  O PHE A 68  ? O PHE AAA 66  
AA1 2 3 N TRP A 67  ? N TRP AAA 65  O PHE A 86  ? O PHE AAA 84  
AA2 1 2 N TYR A 112 ? N TYR AAA 110 O LYS A 116 ? O LYS AAA 114 
# 
_pdbx_entry_details.entry_id                   9GLO 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             NE 
_pdbx_validate_rmsd_angle.auth_asym_id_1             AAA 
_pdbx_validate_rmsd_angle.auth_comp_id_1             ARG 
_pdbx_validate_rmsd_angle.auth_seq_id_1              23 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CZ 
_pdbx_validate_rmsd_angle.auth_asym_id_2             AAA 
_pdbx_validate_rmsd_angle.auth_comp_id_2             ARG 
_pdbx_validate_rmsd_angle.auth_seq_id_2              23 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             NH2 
_pdbx_validate_rmsd_angle.auth_asym_id_3             AAA 
_pdbx_validate_rmsd_angle.auth_comp_id_3             ARG 
_pdbx_validate_rmsd_angle.auth_seq_id_3              23 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                117.26 
_pdbx_validate_rmsd_angle.angle_target_value         120.30 
_pdbx_validate_rmsd_angle.angle_deviation            -3.04 
_pdbx_validate_rmsd_angle.angle_standard_deviation   0.50 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ARG AAA 25 ? ? 57.21 -129.62 
2 1 LEU AAA 75 ? ? 69.01 -4.53   
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 AAA GLY -1  ? A GLY 1   
2 1 Y 1 AAA LYS 162 ? A LYS 164 
3 1 Y 1 AAA GLU 163 ? A GLU 165 
4 1 Y 1 AAA LYS 164 ? A LYS 166 
5 1 Y 1 AAA CYS 165 ? A CYS 167 
6 1 Y 1 AAA ASN 166 ? A ASN 168 
7 1 Y 1 AAA GLN 167 ? A GLN 169 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
GOL C1   C N N 137 
GOL O1   O N N 138 
GOL C2   C N N 139 
GOL O2   O N N 140 
GOL C3   C N N 141 
GOL O3   O N N 142 
GOL H11  H N N 143 
GOL H12  H N N 144 
GOL HO1  H N N 145 
GOL H2   H N N 146 
GOL HO2  H N N 147 
GOL H31  H N N 148 
GOL H32  H N N 149 
GOL HO3  H N N 150 
HIS N    N N N 151 
HIS CA   C N S 152 
HIS C    C N N 153 
HIS O    O N N 154 
HIS CB   C N N 155 
HIS CG   C Y N 156 
HIS ND1  N Y N 157 
HIS CD2  C Y N 158 
HIS CE1  C Y N 159 
HIS NE2  N Y N 160 
HIS OXT  O N N 161 
HIS H    H N N 162 
HIS H2   H N N 163 
HIS HA   H N N 164 
HIS HB2  H N N 165 
HIS HB3  H N N 166 
HIS HD1  H N N 167 
HIS HD2  H N N 168 
HIS HE1  H N N 169 
HIS HE2  H N N 170 
HIS HXT  H N N 171 
HOH O    O N N 172 
HOH H1   H N N 173 
HOH H2   H N N 174 
ILE N    N N N 175 
ILE CA   C N S 176 
ILE C    C N N 177 
ILE O    O N N 178 
ILE CB   C N S 179 
ILE CG1  C N N 180 
ILE CG2  C N N 181 
ILE CD1  C N N 182 
ILE OXT  O N N 183 
ILE H    H N N 184 
ILE H2   H N N 185 
ILE HA   H N N 186 
ILE HB   H N N 187 
ILE HG12 H N N 188 
ILE HG13 H N N 189 
ILE HG21 H N N 190 
ILE HG22 H N N 191 
ILE HG23 H N N 192 
ILE HD11 H N N 193 
ILE HD12 H N N 194 
ILE HD13 H N N 195 
ILE HXT  H N N 196 
LEU N    N N N 197 
LEU CA   C N S 198 
LEU C    C N N 199 
LEU O    O N N 200 
LEU CB   C N N 201 
LEU CG   C N N 202 
LEU CD1  C N N 203 
LEU CD2  C N N 204 
LEU OXT  O N N 205 
LEU H    H N N 206 
LEU H2   H N N 207 
LEU HA   H N N 208 
LEU HB2  H N N 209 
LEU HB3  H N N 210 
LEU HG   H N N 211 
LEU HD11 H N N 212 
LEU HD12 H N N 213 
LEU HD13 H N N 214 
LEU HD21 H N N 215 
LEU HD22 H N N 216 
LEU HD23 H N N 217 
LEU HXT  H N N 218 
LYS N    N N N 219 
LYS CA   C N S 220 
LYS C    C N N 221 
LYS O    O N N 222 
LYS CB   C N N 223 
LYS CG   C N N 224 
LYS CD   C N N 225 
LYS CE   C N N 226 
LYS NZ   N N N 227 
LYS OXT  O N N 228 
LYS H    H N N 229 
LYS H2   H N N 230 
LYS HA   H N N 231 
LYS HB2  H N N 232 
LYS HB3  H N N 233 
LYS HG2  H N N 234 
LYS HG3  H N N 235 
LYS HD2  H N N 236 
LYS HD3  H N N 237 
LYS HE2  H N N 238 
LYS HE3  H N N 239 
LYS HZ1  H N N 240 
LYS HZ2  H N N 241 
LYS HZ3  H N N 242 
LYS HXT  H N N 243 
MET N    N N N 244 
MET CA   C N S 245 
MET C    C N N 246 
MET O    O N N 247 
MET CB   C N N 248 
MET CG   C N N 249 
MET SD   S N N 250 
MET CE   C N N 251 
MET OXT  O N N 252 
MET H    H N N 253 
MET H2   H N N 254 
MET HA   H N N 255 
MET HB2  H N N 256 
MET HB3  H N N 257 
MET HG2  H N N 258 
MET HG3  H N N 259 
MET HE1  H N N 260 
MET HE2  H N N 261 
MET HE3  H N N 262 
MET HXT  H N N 263 
PHE N    N N N 264 
PHE CA   C N S 265 
PHE C    C N N 266 
PHE O    O N N 267 
PHE CB   C N N 268 
PHE CG   C Y N 269 
PHE CD1  C Y N 270 
PHE CD2  C Y N 271 
PHE CE1  C Y N 272 
PHE CE2  C Y N 273 
PHE CZ   C Y N 274 
PHE OXT  O N N 275 
PHE H    H N N 276 
PHE H2   H N N 277 
PHE HA   H N N 278 
PHE HB2  H N N 279 
PHE HB3  H N N 280 
PHE HD1  H N N 281 
PHE HD2  H N N 282 
PHE HE1  H N N 283 
PHE HE2  H N N 284 
PHE HZ   H N N 285 
PHE HXT  H N N 286 
PRO N    N N N 287 
PRO CA   C N S 288 
PRO C    C N N 289 
PRO O    O N N 290 
PRO CB   C N N 291 
PRO CG   C N N 292 
PRO CD   C N N 293 
PRO OXT  O N N 294 
PRO H    H N N 295 
PRO HA   H N N 296 
PRO HB2  H N N 297 
PRO HB3  H N N 298 
PRO HG2  H N N 299 
PRO HG3  H N N 300 
PRO HD2  H N N 301 
PRO HD3  H N N 302 
PRO HXT  H N N 303 
SER N    N N N 304 
SER CA   C N S 305 
SER C    C N N 306 
SER O    O N N 307 
SER CB   C N N 308 
SER OG   O N N 309 
SER OXT  O N N 310 
SER H    H N N 311 
SER H2   H N N 312 
SER HA   H N N 313 
SER HB2  H N N 314 
SER HB3  H N N 315 
SER HG   H N N 316 
SER HXT  H N N 317 
SO4 S    S N N 318 
SO4 O1   O N N 319 
SO4 O2   O N N 320 
SO4 O3   O N N 321 
SO4 O4   O N N 322 
THR N    N N N 323 
THR CA   C N S 324 
THR C    C N N 325 
THR O    O N N 326 
THR CB   C N R 327 
THR OG1  O N N 328 
THR CG2  C N N 329 
THR OXT  O N N 330 
THR H    H N N 331 
THR H2   H N N 332 
THR HA   H N N 333 
THR HB   H N N 334 
THR HG1  H N N 335 
THR HG21 H N N 336 
THR HG22 H N N 337 
THR HG23 H N N 338 
THR HXT  H N N 339 
TRP N    N N N 340 
TRP CA   C N S 341 
TRP C    C N N 342 
TRP O    O N N 343 
TRP CB   C N N 344 
TRP CG   C Y N 345 
TRP CD1  C Y N 346 
TRP CD2  C Y N 347 
TRP NE1  N Y N 348 
TRP CE2  C Y N 349 
TRP CE3  C Y N 350 
TRP CZ2  C Y N 351 
TRP CZ3  C Y N 352 
TRP CH2  C Y N 353 
TRP OXT  O N N 354 
TRP H    H N N 355 
TRP H2   H N N 356 
TRP HA   H N N 357 
TRP HB2  H N N 358 
TRP HB3  H N N 359 
TRP HD1  H N N 360 
TRP HE1  H N N 361 
TRP HE3  H N N 362 
TRP HZ2  H N N 363 
TRP HZ3  H N N 364 
TRP HH2  H N N 365 
TRP HXT  H N N 366 
TYR N    N N N 367 
TYR CA   C N S 368 
TYR C    C N N 369 
TYR O    O N N 370 
TYR CB   C N N 371 
TYR CG   C Y N 372 
TYR CD1  C Y N 373 
TYR CD2  C Y N 374 
TYR CE1  C Y N 375 
TYR CE2  C Y N 376 
TYR CZ   C Y N 377 
TYR OH   O N N 378 
TYR OXT  O N N 379 
TYR H    H N N 380 
TYR H2   H N N 381 
TYR HA   H N N 382 
TYR HB2  H N N 383 
TYR HB3  H N N 384 
TYR HD1  H N N 385 
TYR HD2  H N N 386 
TYR HE1  H N N 387 
TYR HE2  H N N 388 
TYR HH   H N N 389 
TYR HXT  H N N 390 
VAL N    N N N 391 
VAL CA   C N S 392 
VAL C    C N N 393 
VAL O    O N N 394 
VAL CB   C N N 395 
VAL CG1  C N N 396 
VAL CG2  C N N 397 
VAL OXT  O N N 398 
VAL H    H N N 399 
VAL H2   H N N 400 
VAL HA   H N N 401 
VAL HB   H N N 402 
VAL HG11 H N N 403 
VAL HG12 H N N 404 
VAL HG13 H N N 405 
VAL HG21 H N N 406 
VAL HG22 H N N 407 
VAL HG23 H N N 408 
VAL HXT  H N N 409 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
GOL C1  O1   sing N N 129 
GOL C1  C2   sing N N 130 
GOL C1  H11  sing N N 131 
GOL C1  H12  sing N N 132 
GOL O1  HO1  sing N N 133 
GOL C2  O2   sing N N 134 
GOL C2  C3   sing N N 135 
GOL C2  H2   sing N N 136 
GOL O2  HO2  sing N N 137 
GOL C3  O3   sing N N 138 
GOL C3  H31  sing N N 139 
GOL C3  H32  sing N N 140 
GOL O3  HO3  sing N N 141 
HIS N   CA   sing N N 142 
HIS N   H    sing N N 143 
HIS N   H2   sing N N 144 
HIS CA  C    sing N N 145 
HIS CA  CB   sing N N 146 
HIS CA  HA   sing N N 147 
HIS C   O    doub N N 148 
HIS C   OXT  sing N N 149 
HIS CB  CG   sing N N 150 
HIS CB  HB2  sing N N 151 
HIS CB  HB3  sing N N 152 
HIS CG  ND1  sing Y N 153 
HIS CG  CD2  doub Y N 154 
HIS ND1 CE1  doub Y N 155 
HIS ND1 HD1  sing N N 156 
HIS CD2 NE2  sing Y N 157 
HIS CD2 HD2  sing N N 158 
HIS CE1 NE2  sing Y N 159 
HIS CE1 HE1  sing N N 160 
HIS NE2 HE2  sing N N 161 
HIS OXT HXT  sing N N 162 
HOH O   H1   sing N N 163 
HOH O   H2   sing N N 164 
ILE N   CA   sing N N 165 
ILE N   H    sing N N 166 
ILE N   H2   sing N N 167 
ILE CA  C    sing N N 168 
ILE CA  CB   sing N N 169 
ILE CA  HA   sing N N 170 
ILE C   O    doub N N 171 
ILE C   OXT  sing N N 172 
ILE CB  CG1  sing N N 173 
ILE CB  CG2  sing N N 174 
ILE CB  HB   sing N N 175 
ILE CG1 CD1  sing N N 176 
ILE CG1 HG12 sing N N 177 
ILE CG1 HG13 sing N N 178 
ILE CG2 HG21 sing N N 179 
ILE CG2 HG22 sing N N 180 
ILE CG2 HG23 sing N N 181 
ILE CD1 HD11 sing N N 182 
ILE CD1 HD12 sing N N 183 
ILE CD1 HD13 sing N N 184 
ILE OXT HXT  sing N N 185 
LEU N   CA   sing N N 186 
LEU N   H    sing N N 187 
LEU N   H2   sing N N 188 
LEU CA  C    sing N N 189 
LEU CA  CB   sing N N 190 
LEU CA  HA   sing N N 191 
LEU C   O    doub N N 192 
LEU C   OXT  sing N N 193 
LEU CB  CG   sing N N 194 
LEU CB  HB2  sing N N 195 
LEU CB  HB3  sing N N 196 
LEU CG  CD1  sing N N 197 
LEU CG  CD2  sing N N 198 
LEU CG  HG   sing N N 199 
LEU CD1 HD11 sing N N 200 
LEU CD1 HD12 sing N N 201 
LEU CD1 HD13 sing N N 202 
LEU CD2 HD21 sing N N 203 
LEU CD2 HD22 sing N N 204 
LEU CD2 HD23 sing N N 205 
LEU OXT HXT  sing N N 206 
LYS N   CA   sing N N 207 
LYS N   H    sing N N 208 
LYS N   H2   sing N N 209 
LYS CA  C    sing N N 210 
LYS CA  CB   sing N N 211 
LYS CA  HA   sing N N 212 
LYS C   O    doub N N 213 
LYS C   OXT  sing N N 214 
LYS CB  CG   sing N N 215 
LYS CB  HB2  sing N N 216 
LYS CB  HB3  sing N N 217 
LYS CG  CD   sing N N 218 
LYS CG  HG2  sing N N 219 
LYS CG  HG3  sing N N 220 
LYS CD  CE   sing N N 221 
LYS CD  HD2  sing N N 222 
LYS CD  HD3  sing N N 223 
LYS CE  NZ   sing N N 224 
LYS CE  HE2  sing N N 225 
LYS CE  HE3  sing N N 226 
LYS NZ  HZ1  sing N N 227 
LYS NZ  HZ2  sing N N 228 
LYS NZ  HZ3  sing N N 229 
LYS OXT HXT  sing N N 230 
MET N   CA   sing N N 231 
MET N   H    sing N N 232 
MET N   H2   sing N N 233 
MET CA  C    sing N N 234 
MET CA  CB   sing N N 235 
MET CA  HA   sing N N 236 
MET C   O    doub N N 237 
MET C   OXT  sing N N 238 
MET CB  CG   sing N N 239 
MET CB  HB2  sing N N 240 
MET CB  HB3  sing N N 241 
MET CG  SD   sing N N 242 
MET CG  HG2  sing N N 243 
MET CG  HG3  sing N N 244 
MET SD  CE   sing N N 245 
MET CE  HE1  sing N N 246 
MET CE  HE2  sing N N 247 
MET CE  HE3  sing N N 248 
MET OXT HXT  sing N N 249 
PHE N   CA   sing N N 250 
PHE N   H    sing N N 251 
PHE N   H2   sing N N 252 
PHE CA  C    sing N N 253 
PHE CA  CB   sing N N 254 
PHE CA  HA   sing N N 255 
PHE C   O    doub N N 256 
PHE C   OXT  sing N N 257 
PHE CB  CG   sing N N 258 
PHE CB  HB2  sing N N 259 
PHE CB  HB3  sing N N 260 
PHE CG  CD1  doub Y N 261 
PHE CG  CD2  sing Y N 262 
PHE CD1 CE1  sing Y N 263 
PHE CD1 HD1  sing N N 264 
PHE CD2 CE2  doub Y N 265 
PHE CD2 HD2  sing N N 266 
PHE CE1 CZ   doub Y N 267 
PHE CE1 HE1  sing N N 268 
PHE CE2 CZ   sing Y N 269 
PHE CE2 HE2  sing N N 270 
PHE CZ  HZ   sing N N 271 
PHE OXT HXT  sing N N 272 
PRO N   CA   sing N N 273 
PRO N   CD   sing N N 274 
PRO N   H    sing N N 275 
PRO CA  C    sing N N 276 
PRO CA  CB   sing N N 277 
PRO CA  HA   sing N N 278 
PRO C   O    doub N N 279 
PRO C   OXT  sing N N 280 
PRO CB  CG   sing N N 281 
PRO CB  HB2  sing N N 282 
PRO CB  HB3  sing N N 283 
PRO CG  CD   sing N N 284 
PRO CG  HG2  sing N N 285 
PRO CG  HG3  sing N N 286 
PRO CD  HD2  sing N N 287 
PRO CD  HD3  sing N N 288 
PRO OXT HXT  sing N N 289 
SER N   CA   sing N N 290 
SER N   H    sing N N 291 
SER N   H2   sing N N 292 
SER CA  C    sing N N 293 
SER CA  CB   sing N N 294 
SER CA  HA   sing N N 295 
SER C   O    doub N N 296 
SER C   OXT  sing N N 297 
SER CB  OG   sing N N 298 
SER CB  HB2  sing N N 299 
SER CB  HB3  sing N N 300 
SER OG  HG   sing N N 301 
SER OXT HXT  sing N N 302 
SO4 S   O1   doub N N 303 
SO4 S   O2   doub N N 304 
SO4 S   O3   sing N N 305 
SO4 S   O4   sing N N 306 
THR N   CA   sing N N 307 
THR N   H    sing N N 308 
THR N   H2   sing N N 309 
THR CA  C    sing N N 310 
THR CA  CB   sing N N 311 
THR CA  HA   sing N N 312 
THR C   O    doub N N 313 
THR C   OXT  sing N N 314 
THR CB  OG1  sing N N 315 
THR CB  CG2  sing N N 316 
THR CB  HB   sing N N 317 
THR OG1 HG1  sing N N 318 
THR CG2 HG21 sing N N 319 
THR CG2 HG22 sing N N 320 
THR CG2 HG23 sing N N 321 
THR OXT HXT  sing N N 322 
TRP N   CA   sing N N 323 
TRP N   H    sing N N 324 
TRP N   H2   sing N N 325 
TRP CA  C    sing N N 326 
TRP CA  CB   sing N N 327 
TRP CA  HA   sing N N 328 
TRP C   O    doub N N 329 
TRP C   OXT  sing N N 330 
TRP CB  CG   sing N N 331 
TRP CB  HB2  sing N N 332 
TRP CB  HB3  sing N N 333 
TRP CG  CD1  doub Y N 334 
TRP CG  CD2  sing Y N 335 
TRP CD1 NE1  sing Y N 336 
TRP CD1 HD1  sing N N 337 
TRP CD2 CE2  doub Y N 338 
TRP CD2 CE3  sing Y N 339 
TRP NE1 CE2  sing Y N 340 
TRP NE1 HE1  sing N N 341 
TRP CE2 CZ2  sing Y N 342 
TRP CE3 CZ3  doub Y N 343 
TRP CE3 HE3  sing N N 344 
TRP CZ2 CH2  doub Y N 345 
TRP CZ2 HZ2  sing N N 346 
TRP CZ3 CH2  sing Y N 347 
TRP CZ3 HZ3  sing N N 348 
TRP CH2 HH2  sing N N 349 
TRP OXT HXT  sing N N 350 
TYR N   CA   sing N N 351 
TYR N   H    sing N N 352 
TYR N   H2   sing N N 353 
TYR CA  C    sing N N 354 
TYR CA  CB   sing N N 355 
TYR CA  HA   sing N N 356 
TYR C   O    doub N N 357 
TYR C   OXT  sing N N 358 
TYR CB  CG   sing N N 359 
TYR CB  HB2  sing N N 360 
TYR CB  HB3  sing N N 361 
TYR CG  CD1  doub Y N 362 
TYR CG  CD2  sing Y N 363 
TYR CD1 CE1  sing Y N 364 
TYR CD1 HD1  sing N N 365 
TYR CD2 CE2  doub Y N 366 
TYR CD2 HD2  sing N N 367 
TYR CE1 CZ   doub Y N 368 
TYR CE1 HE1  sing N N 369 
TYR CE2 CZ   sing Y N 370 
TYR CE2 HE2  sing N N 371 
TYR CZ  OH   sing N N 372 
TYR OH  HH   sing N N 373 
TYR OXT HXT  sing N N 374 
VAL N   CA   sing N N 375 
VAL N   H    sing N N 376 
VAL N   H2   sing N N 377 
VAL CA  C    sing N N 378 
VAL CA  CB   sing N N 379 
VAL CA  HA   sing N N 380 
VAL C   O    doub N N 381 
VAL C   OXT  sing N N 382 
VAL CB  CG1  sing N N 383 
VAL CB  CG2  sing N N 384 
VAL CB  HB   sing N N 385 
VAL CG1 HG11 sing N N 386 
VAL CG1 HG12 sing N N 387 
VAL CG1 HG13 sing N N 388 
VAL CG2 HG21 sing N N 389 
VAL CG2 HG22 sing N N 390 
VAL CG2 HG23 sing N N 391 
VAL OXT HXT  sing N N 392 
# 
_pdbx_audit_support.funding_organization   'Israel Science Foundation' 
_pdbx_audit_support.country                Israel 
_pdbx_audit_support.grant_number           491/2021 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   2Z6O 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9GLO 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.021367 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.021367 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006926 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.310  20.844 1.020 10.208 1.589 0.569  0.865 51.651 0.216   
H 1  1  0.493  10.511 0.323 26.126 0.140 3.142  0.041 57.800 0.003   
N 7  7  12.222 0.006  3.135 9.893  2.014 28.997 1.167 0.583  -11.538 
O 8  8  3.049  13.277 2.287 5.701  1.546 0.324  0.867 32.909 0.251   
S 16 16 6.905  1.468  5.203 22.215 1.438 0.254  1.586 56.172 1.018   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N   . SER A 1 2   ? 23.198  24.394 5.926  1.000 33.580 0 0   SER AAA N   1 ? 
ATOM   2    C CA  . SER A 1 2   ? 21.749  24.696 6.056  1.000 26.799 0 0   SER AAA CA  1 ? 
ATOM   3    C C   . SER A 1 2   ? 21.378  24.765 7.551  1.000 23.506 0 0   SER AAA C   1 ? 
ATOM   4    O O   . SER A 1 2   ? 21.509  23.756 8.299  1.000 22.028 0 0   SER AAA O   1 ? 
ATOM   5    C CB  . SER A 1 2   ? 20.916  23.678 5.342  1.000 30.430 0 0   SER AAA CB  1 ? 
ATOM   6    O OG  . SER A 1 2   ? 19.567  23.709 5.756  1.000 25.450 0 0   SER AAA OG  1 ? 
ATOM   7    N N   . MET A 1 3   ? 20.980  25.954 8.003  1.000 20.944 0 1   MET AAA N   1 ? 
ATOM   8    C CA  . MET A 1 3   ? 20.360  26.110 9.353  1.000 18.405 0 1   MET AAA CA  1 ? 
ATOM   9    C C   . MET A 1 3   ? 19.183  25.151 9.499  1.000 17.516 0 1   MET AAA C   1 ? 
ATOM   10   O O   . MET A 1 3   ? 19.028  24.606 10.620 1.000 15.752 0 1   MET AAA O   1 ? 
ATOM   11   C CB  . MET A 1 3   ? 19.809  27.527 9.556  1.000 20.151 0 1   MET AAA CB  1 ? 
ATOM   12   C CG  . MET A 1 3   ? 20.775  28.425 10.170 1.000 20.948 0 1   MET AAA CG  1 ? 
ATOM   13   S SD  . MET A 1 3   ? 19.901  29.910 10.899 1.000 19.462 0 1   MET AAA SD  1 ? 
ATOM   14   C CE  . MET A 1 3   ? 19.483  29.529 12.579 1.000 20.427 0 1   MET AAA CE  1 ? 
ATOM   15   N N   . ALA A 1 4   ? 18.258  25.050 8.539  1.000 17.982 0 2   ALA AAA N   1 ? 
ATOM   16   C CA  . ALA A 1 4   ? 17.075  24.174 8.656  1.000 17.753 0 2   ALA AAA CA  1 ? 
ATOM   17   C C   . ALA A 1 4   ? 17.565  22.740 8.883  1.000 16.977 0 2   ALA AAA C   1 ? 
ATOM   18   O O   . ALA A 1 4   ? 17.000  22.065 9.719  1.000 16.035 0 2   ALA AAA O   1 ? 
ATOM   19   C CB  . ALA A 1 4   ? 16.145  24.252 7.455  1.000 20.268 0 2   ALA AAA CB  1 ? 
ATOM   20   N N   . ASP A 1 5   ? 18.542  22.274 8.105  1.000 17.605 0 3   ASP AAA N   1 ? 
ATOM   21   C CA  . ASP A 1 5   ? 19.014  20.867 8.242  1.000 17.444 0 3   ASP AAA CA  1 ? 
ATOM   22   C C   . ASP A 1 5   ? 19.615  20.639 9.629  1.000 16.315 0 3   ASP AAA C   1 ? 
ATOM   23   O O   . ASP A 1 5   ? 19.279  19.644 10.272 1.000 16.489 0 3   ASP AAA O   1 ? 
ATOM   24   C CB  . ASP A 1 5   ? 20.038  20.502 7.169  1.000 21.784 0 3   ASP AAA CB  1 ? 
ATOM   25   C CG  . ASP A 1 5   ? 19.431  20.363 5.791  1.000 27.136 0 3   ASP AAA CG  1 ? 
ATOM   26   O OD1 . ASP A 1 5   ? 18.214  20.453 5.661  1.000 25.378 0 3   ASP AAA OD1 1 ? 
ATOM   27   O OD2 . ASP A 1 5   ? 20.206  20.218 4.877  1.000 33.569 0 3   ASP AAA OD2 1 ? 
ATOM   28   N N   . GLU A 1 6   ? 20.404  21.576 10.154 1.000 13.913 0 4   GLU AAA N   1 ? 
ATOM   29   C CA  . GLU A 1 6   ? 20.979  21.414 11.489 1.000 13.929 0 4   GLU AAA CA  1 ? 
ATOM   30   C C   . GLU A 1 6   ? 19.871  21.448 12.537 1.000 13.298 0 4   GLU AAA C   1 ? 
ATOM   31   O O   . GLU A 1 6   ? 19.955  20.699 13.555 1.000 12.405 0 4   GLU AAA O   1 ? 
ATOM   32   C CB  . GLU A 1 6   ? 22.057  22.449 11.757 1.000 15.986 0 4   GLU AAA CB  1 ? 
ATOM   33   C CG  . GLU A 1 6   ? 22.702  22.232 13.100 1.000 18.509 0 4   GLU AAA CG  1 ? 
ATOM   34   C CD  . GLU A 1 6   ? 23.525  20.953 13.295 1.000 21.831 0 4   GLU AAA CD  1 ? 
ATOM   35   O OE1 . GLU A 1 6   ? 23.772  20.280 12.284 1.000 23.656 0 4   GLU AAA OE1 1 ? 
ATOM   36   O OE2 . GLU A 1 6   ? 23.895  20.637 14.437 1.000 22.961 0 4   GLU AAA OE2 1 ? 
ATOM   37   N N   . ALA A 1 7   ? 18.920  22.392 12.420 1.000 12.845 0 5   ALA AAA N   1 ? 
ATOM   38   C CA  . ALA A 1 7   ? 17.868  22.463 13.434 1.000 12.117 0 5   ALA AAA CA  1 ? 
ATOM   39   C C   . ALA A 1 7   ? 17.072  21.147 13.461 1.000 12.726 0 5   ALA AAA C   1 ? 
ATOM   40   O O   . ALA A 1 7   ? 16.699  20.658 14.542 1.000 13.166 0 5   ALA AAA O   1 ? 
ATOM   41   C CB  . ALA A 1 7   ? 16.961  23.644 13.164 1.000 13.449 0 5   ALA AAA CB  1 ? 
ATOM   42   N N   . THR A 1 8   ? 16.772  20.596 12.297 1.000 12.747 0 6   THR AAA N   1 ? 
ATOM   43   C CA  . THR A 1 8   ? 16.043  19.319 12.247 1.000 12.482 0 6   THR AAA CA  1 ? 
ATOM   44   C C   . THR A 1 8   ? 16.872  18.220 12.930 1.000 12.999 0 6   THR AAA C   1 ? 
ATOM   45   O O   . THR A 1 8   ? 16.320  17.505 13.813 1.000 13.236 0 6   THR AAA O   1 ? 
ATOM   46   C CB  . THR A 1 8   ? 15.745  18.929 10.794 1.000 13.592 0 6   THR AAA CB  1 ? 
ATOM   47   O OG1 . THR A 1 8   ? 14.933  19.958 10.229 1.000 15.948 0 6   THR AAA OG1 1 ? 
ATOM   48   C CG2 . THR A 1 8   ? 14.982  17.635 10.689 1.000 14.799 0 6   THR AAA CG2 1 ? 
ATOM   49   N N   . ARG A 1 9   ? 18.143  18.102 12.595 1.000 13.051 0 7   ARG AAA N   1 ? 
ATOM   50   C CA  . ARG A 1 9   ? 19.007  17.051 13.196 1.000 14.088 0 7   ARG AAA CA  1 ? 
ATOM   51   C C   . ARG A 1 9   ? 19.056  17.229 14.719 1.000 12.945 0 7   ARG AAA C   1 ? 
ATOM   52   O O   . ARG A 1 9   ? 19.031  16.227 15.441 1.000 14.728 0 7   ARG AAA O   1 ? 
ATOM   53   C CB  . ARG A 1 9   ? 20.406  17.175 12.592 1.000 17.274 0 7   ARG AAA CB  1 ? 
ATOM   54   C CG  . ARG A 1 9   ? 21.323  15.981 12.718 1.000 25.732 0 7   ARG AAA CG  1 ? 
ATOM   55   C CD  . ARG A 1 9   ? 22.736  16.414 12.311 1.000 29.695 0 7   ARG AAA CD  1 ? 
ATOM   56   N NE  . ARG A 1 9   ? 23.288  17.380 13.256 1.000 32.301 0 7   ARG AAA NE  1 ? 
ATOM   57   C CZ  . ARG A 1 9   ? 23.799  17.097 14.445 1.000 34.813 0 7   ARG AAA CZ  1 ? 
ATOM   58   N NH1 . ARG A 1 9   ? 23.888  15.846 14.868 1.000 37.599 0 7   ARG AAA NH1 1 ? 
ATOM   59   N NH2 . ARG A 1 9   ? 24.217  18.081 15.222 1.000 33.872 0 7   ARG AAA NH2 1 ? 
ATOM   60   N N   . ARG A 1 10  ? 19.168  18.467 15.214 1.000 12.345 0 8   ARG AAA N   1 ? 
ATOM   61   C CA  . ARG A 1 10  ? 19.293  18.673 16.685 1.000 12.133 0 8   ARG AAA CA  1 ? 
ATOM   62   C C   . ARG A 1 10  ? 18.043  18.134 17.351 1.000 13.753 0 8   ARG AAA C   1 ? 
ATOM   63   O O   . ARG A 1 10  ? 18.179  17.551 18.430 1.000 15.801 0 8   ARG AAA O   1 ? 
ATOM   64   C CB  . ARG A 1 10  ? 19.539  20.142 17.012 1.000 13.240 0 8   ARG AAA CB  1 ? 
ATOM   65   C CG  . ARG A 1 10  ? 20.914  20.648 16.588 1.000 15.187 0 8   ARG AAA CG  1 ? 
ATOM   66   C CD  . ARG A 1 10  ? 21.958  20.366 17.650 1.000 16.972 0 8   ARG AAA CD  1 ? 
ATOM   67   N NE  . ARG A 1 10  ? 23.242  20.892 17.180 1.000 18.695 0 8   ARG AAA NE  1 ? 
ATOM   68   C CZ  . ARG A 1 10  ? 24.330  21.095 17.907 1.000 21.715 0 8   ARG AAA CZ  1 ? 
ATOM   69   N NH1 . ARG A 1 10  ? 24.332  20.770 19.184 1.000 21.761 0 8   ARG AAA NH1 1 ? 
ATOM   70   N NH2 . ARG A 1 10  ? 25.418  21.585 17.322 1.000 21.229 0 8   ARG AAA NH2 1 ? 
ATOM   71   N N   . VAL A 1 11  ? 16.868  18.377 16.766 1.000 11.495 0 9   VAL AAA N   1 ? 
ATOM   72   C CA  . VAL A 1 11  ? 15.610  17.993 17.417 1.000 13.843 0 9   VAL AAA CA  1 ? 
ATOM   73   C C   . VAL A 1 11  ? 15.411  16.474 17.323 1.000 13.437 0 9   VAL AAA C   1 ? 
ATOM   74   O O   . VAL A 1 11  ? 14.952  15.896 18.339 1.000 17.841 0 9   VAL AAA O   1 ? 
ATOM   75   C CB  . VAL A 1 11  ? 14.436  18.800 16.851 1.000 14.276 0 9   VAL AAA CB  1 ? 
ATOM   76   C CG1 . VAL A 1 11  ? 13.113  18.174 17.338 1.000 17.772 0 9   VAL AAA CG1 1 ? 
ATOM   77   C CG2 . VAL A 1 11  ? 14.521  20.268 17.209 1.000 15.195 0 9   VAL AAA CG2 1 ? 
ATOM   78   N N   . VAL A 1 12  ? 15.754  15.814 16.226 1.000 13.728 0 10  VAL AAA N   1 ? 
ATOM   79   C CA  . VAL A 1 12  ? 15.369  14.383 16.033 1.000 14.981 0 10  VAL AAA CA  1 ? 
ATOM   80   C C   . VAL A 1 12  ? 16.526  13.384 16.063 1.000 16.385 0 10  VAL AAA C   1 ? 
ATOM   81   O O   . VAL A 1 12  ? 16.244  12.231 15.901 1.000 16.530 0 10  VAL AAA O   1 ? 
ATOM   82   C CB  . VAL A 1 12  ? 14.557  14.201 14.744 1.000 17.088 0 10  VAL AAA CB  1 ? 
ATOM   83   C CG1 . VAL A 1 12  ? 13.360  15.129 14.757 1.000 18.093 0 10  VAL AAA CG1 1 ? 
ATOM   84   C CG2 . VAL A 1 12  ? 15.364  14.365 13.505 1.000 19.438 0 10  VAL AAA CG2 1 ? 
ATOM   85   N N   . SER A 1 13  ? 17.799  13.742 16.159 1.000 20.050 0 11  SER AAA N   1 ? 
ATOM   86   C CA  . SER A 1 13  ? 18.877  12.736 15.869 1.000 21.428 0 11  SER AAA CA  1 ? 
ATOM   87   C C   . SER A 1 13  ? 18.889  11.493 16.798 1.000 22.320 0 11  SER AAA C   1 ? 
ATOM   88   O O   . SER A 1 13  ? 19.525  10.512 16.356 1.000 26.519 0 11  SER AAA O   1 ? 
ATOM   89   C CB  . SER A 1 13  ? 20.251  13.401 15.823 1.000 22.024 0 11  SER AAA CB  1 ? 
ATOM   90   O OG  . SER A 1 13  ? 20.607  13.873 17.110 1.000 25.966 0 11  SER AAA OG  1 ? 
ATOM   91   N N   . GLU A 1 14  ? 18.376  11.533 18.052 1.000 18.347 0 12  GLU AAA N   1 ? 
ATOM   92   C CA  . GLU A 1 14  ? 18.331  10.381 18.973 1.000 17.059 0 12  GLU AAA CA  1 ? 
ATOM   93   C C   . GLU A 1 14  ? 16.986  9.634  18.882 1.000 14.757 0 12  GLU AAA C   1 ? 
ATOM   94   O O   . GLU A 1 14  ? 16.744  8.701  19.702 1.000 15.175 0 12  GLU AAA O   1 ? 
ATOM   95   C CB  . GLU A 1 14  ? 18.556  10.814 20.428 1.000 20.508 0 12  GLU AAA CB  1 ? 
ATOM   96   C CG  . GLU A 1 14  ? 19.838  11.611 20.582 1.000 27.435 0 12  GLU AAA CG  1 ? 
ATOM   97   C CD  . GLU A 1 14  ? 20.301  11.839 22.008 1.000 32.311 0 12  GLU AAA CD  1 ? 
ATOM   98   O OE1 . GLU A 1 14  ? 19.900  12.868 22.586 1.000 37.913 0 12  GLU AAA OE1 1 ? 
ATOM   99   O OE2 . GLU A 1 14  ? 21.087  10.993 22.511 1.000 42.132 0 12  GLU AAA OE2 1 ? 
ATOM   100  N N   . ILE A 1 15  ? 16.148  9.975  17.902 1.000 13.053 0 13  ILE AAA N   1 ? 
ATOM   101  C CA  . ILE A 1 15  ? 14.869  9.238  17.637 1.000 12.592 0 13  ILE AAA CA  1 ? 
ATOM   102  C C   . ILE A 1 15  ? 15.199  8.182  16.581 1.000 11.982 0 13  ILE AAA C   1 ? 
ATOM   103  O O   . ILE A 1 15  ? 15.743  8.482  15.522 1.000 12.756 0 13  ILE AAA O   1 ? 
ATOM   104  C CB  . ILE A 1 15  ? 13.729  10.168 17.178 1.000 12.695 0 13  ILE AAA CB  1 ? 
ATOM   105  C CG1 . ILE A 1 15  ? 13.483  11.272 18.209 1.000 13.430 0 13  ILE AAA CG1 1 ? 
ATOM   106  C CG2 . ILE A 1 15  ? 12.490  9.363  16.851 1.000 12.288 0 13  ILE AAA CG2 1 ? 
ATOM   107  C CD1 . ILE A 1 15  ? 12.428  12.302 17.790 1.000 14.275 0 13  ILE AAA CD1 1 ? 
ATOM   108  N N   . PRO A 1 16  ? 14.884  6.888  16.795 1.000 11.448 0 14  PRO AAA N   1 ? 
ATOM   109  C CA  . PRO A 1 16  ? 15.124  5.893  15.775 1.000 12.177 0 14  PRO AAA CA  1 ? 
ATOM   110  C C   . PRO A 1 16  ? 14.429  6.284  14.476 1.000 12.095 0 14  PRO AAA C   1 ? 
ATOM   111  O O   . PRO A 1 16  ? 13.259  6.670  14.455 1.000 11.094 0 14  PRO AAA O   1 ? 
ATOM   112  C CB  . PRO A 1 16  ? 14.577  4.599  16.407 1.000 11.339 0 14  PRO AAA CB  1 ? 
ATOM   113  C CG  . PRO A 1 16  ? 14.639  4.842  17.891 1.000 12.171 0 14  PRO AAA CG  1 ? 
ATOM   114  C CD  . PRO A 1 16  ? 14.345  6.301  18.036 1.000 11.684 0 14  PRO AAA CD  1 ? 
ATOM   115  N N   . VAL A 1 17  ? 15.151  6.121  13.363 1.000 12.393 0 15  VAL AAA N   1 ? 
ATOM   116  C CA  . VAL A 1 17  ? 14.606  6.388  12.017 1.000 13.209 0 15  VAL AAA CA  1 ? 
ATOM   117  C C   . VAL A 1 17  ? 13.698  5.210  11.609 1.000 11.370 0 15  VAL AAA C   1 ? 
ATOM   118  O O   . VAL A 1 17  ? 13.970  4.047  12.039 1.000 13.918 0 15  VAL AAA O   1 ? 
ATOM   119  C CB  . VAL A 1 17  ? 15.810  6.608  11.081 1.000 15.396 0 15  VAL AAA CB  1 ? 
ATOM   120  C CG1 . VAL A 1 17  ? 15.388  6.799  9.650  1.000 18.200 0 15  VAL AAA CG1 1 ? 
ATOM   121  C CG2 . VAL A 1 17  ? 16.657  7.784  11.568 1.000 16.338 0 15  VAL AAA CG2 1 ? 
ATOM   122  N N   . LEU A 1 18  ? 12.675  5.448  10.804 1.000 11.791 0 16  LEU AAA N   1 ? 
ATOM   123  C CA  . LEU A 1 18  ? 11.807  4.391  10.304 1.000 12.540 0 16  LEU AAA CA  1 ? 
ATOM   124  C C   . LEU A 1 18  ? 12.168  4.028  8.863  1.000 13.118 0 16  LEU AAA C   1 ? 
ATOM   125  O O   . LEU A 1 18  ? 13.012  4.697  8.269  1.000 14.411 0 16  LEU AAA O   1 ? 
ATOM   126  C CB  . LEU A 1 18  ? 10.356  4.840  10.448 1.000 13.300 0 16  LEU AAA CB  1 ? 
ATOM   127  C CG  . LEU A 1 18  ? 9.832   4.964  11.907 1.000 12.571 0 16  LEU AAA CG  1 ? 
ATOM   128  C CD1 . LEU A 1 18  ? 10.168  6.320  12.523 1.000 12.950 0 16  LEU AAA CD1 1 ? 
ATOM   129  C CD2 . LEU A 1 18  ? 8.335   4.795  11.956 1.000 13.693 0 16  LEU AAA CD2 1 ? 
ATOM   130  N N   . LYS A 1 19  ? 11.665  2.898  8.428  1.000 14.877 0 17  LYS AAA N   1 ? 
ATOM   131  C CA  . LYS A 1 19  ? 12.170  2.285  7.183  1.000 16.069 0 17  LYS AAA CA  1 ? 
ATOM   132  C C   . LYS A 1 19  ? 11.025  1.956  6.245  1.000 14.405 0 17  LYS AAA C   1 ? 
ATOM   133  O O   . LYS A 1 19  ? 11.148  2.219  5.009  1.000 15.514 0 17  LYS AAA O   1 ? 
ATOM   134  C CB  . LYS A 1 19  ? 12.883  0.975  7.507  1.000 20.127 0 17  LYS AAA CB  1 ? 
ATOM   135  C CG  . LYS A 1 19  ? 13.608  0.390  6.310  1.000 27.876 0 17  LYS AAA CG  1 ? 
ATOM   136  C CD  . LYS A 1 19  ? 13.397  -1.089 6.345  1.000 28.435 0 17  LYS AAA CD  1 ? 
ATOM   137  C CE  . LYS A 1 19  ? 13.023  -1.633 4.994  1.000 34.731 0 17  LYS AAA CE  1 ? 
ATOM   138  N NZ  . LYS A 1 19  ? 12.996  -3.093 5.082  1.000 33.389 0 17  LYS AAA NZ  1 ? 
ATOM   139  N N   . THR A 1 20  ? 9.942   1.357  6.721  1.000 13.451 0 18  THR AAA N   1 ? 
ATOM   140  C CA  . THR A 1 20  ? 9.013   0.683  5.796  1.000 13.532 0 18  THR AAA CA  1 ? 
ATOM   141  C C   . THR A 1 20  ? 8.048   1.685  5.155  1.000 13.749 0 18  THR AAA C   1 ? 
ATOM   142  O O   . THR A 1 20  ? 7.306   2.372  5.872  1.000 14.549 0 18  THR AAA O   1 ? 
ATOM   143  C CB  . THR A 1 20  ? 8.263   -0.464 6.483  1.000 14.298 0 18  THR AAA CB  1 ? 
ATOM   144  O OG1 . THR A 1 20  ? 9.260   -1.371 6.982  1.000 13.777 0 18  THR AAA OG1 1 ? 
ATOM   145  C CG2 . THR A 1 20  ? 7.287   -1.167 5.583  1.000 13.415 0 18  THR AAA CG2 1 ? 
ATOM   146  N N   . ASN A 1 21  ? 7.919   1.635  3.821  1.000 13.736 0 19  ASN AAA N   1 ? 
ATOM   147  C CA  . ASN A 1 21  ? 6.859   2.375  3.111  1.000 16.487 0 19  ASN AAA CA  1 ? 
ATOM   148  C C   . ASN A 1 21  ? 5.564   1.574  3.069  1.000 16.258 0 19  ASN AAA C   1 ? 
ATOM   149  O O   . ASN A 1 21  ? 5.318   0.739  2.123  1.000 19.923 0 19  ASN AAA O   1 ? 
ATOM   150  C CB  . ASN A 1 21  ? 7.242   2.585  1.643  1.000 18.708 0 19  ASN AAA CB  1 ? 
ATOM   151  C CG  . ASN A 1 21  ? 6.114   3.244  0.921  1.000 20.899 0 19  ASN AAA CG  1 ? 
ATOM   152  O OD1 . ASN A 1 21  ? 5.458   4.089  1.537  1.000 19.714 0 19  ASN AAA OD1 1 ? 
ATOM   153  N ND2 . ASN A 1 21  ? 5.933   2.879  -0.353 1.000 23.003 0 19  ASN AAA ND2 1 ? 
ATOM   154  N N   . ALA A 1 22  ? 4.758   1.701  4.110  1.000 12.198 0 20  ALA AAA N   1 ? 
ATOM   155  C CA  . ALA A 1 22  ? 3.480   0.994  4.170  1.000 12.342 0 20  ALA AAA CA  1 ? 
ATOM   156  C C   . ALA A 1 22  ? 2.461   1.813  4.956  1.000 13.000 0 20  ALA AAA C   1 ? 
ATOM   157  O O   . ALA A 1 22  ? 2.830   2.403  6.004  1.000 12.886 0 20  ALA AAA O   1 ? 
ATOM   158  C CB  . ALA A 1 22  ? 3.664   -0.350 4.827  1.000 13.746 0 20  ALA AAA CB  1 ? 
ATOM   159  N N   . GLY A 1 23  ? 1.222   1.763  4.528  1.000 12.900 0 21  GLY AAA N   1 ? 
ATOM   160  C CA  . GLY A 1 23  ? 0.089   2.315  5.257  1.000 12.658 0 21  GLY AAA CA  1 ? 
ATOM   161  C C   . GLY A 1 23  ? -0.891  1.258  5.720  1.000 13.136 0 21  GLY AAA C   1 ? 
ATOM   162  O O   . GLY A 1 23  ? -0.637  0.074  5.548  1.000 13.175 0 21  GLY AAA O   1 ? 
ATOM   163  N N   . PRO A 1 24  ? -2.032  1.691  6.288  1.000 13.243 0 22  PRO AAA N   1 ? 
ATOM   164  C CA  . PRO A 1 24  ? -3.003  0.810  6.944  1.000 15.483 0 22  PRO AAA CA  1 ? 
ATOM   165  C C   . PRO A 1 24  ? -3.589  -0.350 6.128  1.000 17.011 0 22  PRO AAA C   1 ? 
ATOM   166  O O   . PRO A 1 24  ? -3.982  -1.300 6.735  1.000 19.229 0 22  PRO AAA O   1 ? 
ATOM   167  C CB  . PRO A 1 24  ? -4.170  1.718  7.337  1.000 17.321 0 22  PRO AAA CB  1 ? 
ATOM   168  C CG  . PRO A 1 24  ? -3.597  3.080  7.353  1.000 16.762 0 22  PRO AAA CG  1 ? 
ATOM   169  C CD  . PRO A 1 24  ? -2.356  3.107  6.505  1.000 13.517 0 22  PRO AAA CD  1 ? 
ATOM   170  N N   . ARG A 1 25  ? -3.557  -0.277 4.817  1.000 17.380 0 23  ARG AAA N   1 ? 
ATOM   171  C CA  . ARG A 1 25  ? -4.146  -1.365 3.998  1.000 17.924 0 23  ARG AAA CA  1 ? 
ATOM   172  C C   . ARG A 1 25  ? -3.043  -2.361 3.634  1.000 19.068 0 23  ARG AAA C   1 ? 
ATOM   173  O O   . ARG A 1 25  ? -3.345  -3.334 2.916  1.000 20.276 0 23  ARG AAA O   1 ? 
ATOM   174  C CB  . ARG A 1 25  ? -4.822  -0.746 2.763  1.000 18.644 0 23  ARG AAA CB  1 ? 
ATOM   175  C CG  . ARG A 1 25  ? -6.026  0.125  3.114  1.000 23.678 0 23  ARG AAA CG  1 ? 
ATOM   176  C CD  . ARG A 1 25  ? -6.860  0.622  1.939  1.000 28.150 0 23  ARG AAA CD  1 ? 
ATOM   177  N NE  . ARG A 1 25  ? -6.026  0.654  0.773  1.000 34.710 0 23  ARG AAA NE  1 ? 
ATOM   178  C CZ  . ARG A 1 25  ? -6.355  1.149  -0.409 1.000 38.589 0 23  ARG AAA CZ  1 ? 
ATOM   179  N NH1 . ARG A 1 25  ? -7.548  1.700  -0.595 1.000 30.869 0 23  ARG AAA NH1 1 ? 
ATOM   180  N NH2 . ARG A 1 25  ? -5.428  1.116  -1.363 1.000 31.855 0 23  ARG AAA NH2 1 ? 
ATOM   181  N N   . ASP A 1 26  ? -1.784  -2.189 4.054  1.000 15.649 0 24  ASP AAA N   1 ? 
ATOM   182  C CA  . ASP A 1 26  ? -0.649  -2.960 3.487  1.000 15.638 0 24  ASP AAA CA  1 ? 
ATOM   183  C C   . ASP A 1 26  ? -0.282  -4.227 4.289  1.000 14.020 0 24  ASP AAA C   1 ? 
ATOM   184  O O   . ASP A 1 26  ? 0.828   -4.721 4.086  1.000 15.132 0 24  ASP AAA O   1 ? 
ATOM   185  C CB  . ASP A 1 26  ? 0.515   -2.018 3.210  1.000 15.247 0 24  ASP AAA CB  1 ? 
ATOM   186  C CG  . ASP A 1 26  ? 0.165   -0.993 2.176  1.000 20.085 0 24  ASP AAA CG  1 ? 
ATOM   187  O OD1 . ASP A 1 26  ? -0.675  -1.310 1.305  1.000 26.557 0 24  ASP AAA OD1 1 ? 
ATOM   188  O OD2 . ASP A 1 26  ? 0.686   0.091  2.237  1.000 17.160 0 24  ASP AAA OD2 1 ? 
ATOM   189  N N   . ARG A 1 27  ? -1.164  -4.763 5.117  1.000 16.579 0 25  ARG AAA N   1 ? 
ATOM   190  C CA  . ARG A 1 27  ? -1.051  -6.155 5.642  1.000 16.276 0 25  ARG AAA CA  1 ? 
ATOM   191  C C   . ARG A 1 27  ? 0.281   -6.326 6.361  1.000 15.800 0 25  ARG AAA C   1 ? 
ATOM   192  O O   . ARG A 1 27  ? 0.519   -5.578 7.356  1.000 15.697 0 25  ARG AAA O   1 ? 
ATOM   193  C CB  . ARG A 1 27  ? -1.218  -7.161 4.486  1.000 20.619 0 25  ARG AAA CB  1 ? 
ATOM   194  C CG  . ARG A 1 27  ? -2.499  -7.010 3.675  1.000 27.261 0 25  ARG AAA CG  1 ? 
ATOM   195  C CD  . ARG A 1 27  ? -3.750  -7.138 4.512  1.000 30.951 0 25  ARG AAA CD  1 ? 
ATOM   196  N N   . GLU A 1 28  ? 1.065   -7.364 6.055  1.000 16.159 0 26  GLU AAA N   1 ? 
ATOM   197  C CA  . GLU A 1 28  ? 2.271   -7.638 6.856  1.000 15.561 0 26  GLU AAA CA  1 ? 
ATOM   198  C C   . GLU A 1 28  ? 3.244   -6.465 6.827  1.000 14.536 0 26  GLU AAA C   1 ? 
ATOM   199  O O   . GLU A 1 28  ? 4.053   -6.326 7.815  1.000 13.580 0 26  GLU AAA O   1 ? 
ATOM   200  C CB  . GLU A 1 28  ? 2.966   -8.925 6.404  1.000 18.820 0 26  GLU AAA CB  1 ? 
ATOM   201  C CG  . GLU A 1 28  ? 3.529   -8.898 5.003  1.000 21.344 0 26  GLU AAA CG  1 ? 
ATOM   202  C CD  . GLU A 1 28  ? 2.575   -8.891 3.800  1.000 25.552 0 26  GLU AAA CD  1 ? 
ATOM   203  O OE1 . GLU A 1 28  ? 1.378   -9.121 3.956  1.000 23.371 0 26  GLU AAA OE1 1 ? 
ATOM   204  O OE2 . GLU A 1 28  ? 3.066   -8.626 2.716  1.000 29.949 0 26  GLU AAA OE2 1 ? 
ATOM   205  N N   . LEU A 1 29  ? 3.277   -5.662 5.755  1.000 13.391 0 27  LEU AAA N   1 ? 
ATOM   206  C CA  . LEU A 1 29  ? 4.188   -4.497 5.712  1.000 12.206 0 27  LEU AAA CA  1 ? 
ATOM   207  C C   . LEU A 1 29  ? 3.677   -3.440 6.717  1.000 12.564 0 27  LEU AAA C   1 ? 
ATOM   208  O O   . LEU A 1 29  ? 4.549   -2.741 7.255  1.000 11.888 0 27  LEU AAA O   1 ? 
ATOM   209  C CB  . LEU A 1 29  ? 4.313   -3.968 4.272  1.000 14.312 0 27  LEU AAA CB  1 ? 
ATOM   210  C CG  . LEU A 1 29  ? 4.998   -4.940 3.301  1.000 16.607 0 27  LEU AAA CG  1 ? 
ATOM   211  C CD1 . LEU A 1 29  ? 5.006   -4.373 1.906  1.000 17.703 0 27  LEU AAA CD1 1 ? 
ATOM   212  C CD2 . LEU A 1 29  ? 6.416   -5.276 3.697  1.000 20.219 0 27  LEU AAA CD2 1 ? 
ATOM   213  N N   . TRP A 1 30  ? 2.382   -3.272 6.864  1.000 13.477 0 28  TRP AAA N   1 ? 
ATOM   214  C CA  . TRP A 1 30  ? 1.815   -2.326 7.855  1.000 12.384 0 28  TRP AAA CA  1 ? 
ATOM   215  C C   . TRP A 1 30  ? 2.135   -2.791 9.274  1.000 12.417 0 28  TRP AAA C   1 ? 
ATOM   216  O O   . TRP A 1 30  ? 2.597   -1.975 10.104 1.000 12.179 0 28  TRP AAA O   1 ? 
ATOM   217  C CB  . TRP A 1 30  ? 0.311   -2.174 7.636  1.000 13.582 0 28  TRP AAA CB  1 ? 
ATOM   218  C CG  . TRP A 1 30  ? -0.340  -1.294 8.662  1.000 13.169 0 28  TRP AAA CG  1 ? 
ATOM   219  C CD1 . TRP A 1 30  ? -1.383  -1.633 9.478  1.000 14.369 0 28  TRP AAA CD1 1 ? 
ATOM   220  C CD2 . TRP A 1 30  ? 0.001   0.079  8.974  1.000 12.776 0 28  TRP AAA CD2 1 ? 
ATOM   221  N NE1 . TRP A 1 30  ? -1.752  -0.541 10.239 1.000 14.081 0 28  TRP AAA NE1 1 ? 
ATOM   222  C CE2 . TRP A 1 30  ? -0.896  0.499  9.973  1.000 13.586 0 28  TRP AAA CE2 1 ? 
ATOM   223  C CE3 . TRP A 1 30  ? 0.970   0.987  8.527  1.000 13.598 0 28  TRP AAA CE3 1 ? 
ATOM   224  C CZ2 . TRP A 1 30  ? -0.855  1.799  10.473 1.000 14.019 0 28  TRP AAA CZ2 1 ? 
ATOM   225  C CZ3 . TRP A 1 30  ? 1.011   2.267  9.040  1.000 14.164 0 28  TRP AAA CZ3 1 ? 
ATOM   226  C CH2 . TRP A 1 30  ? 0.139   2.638  10.059 1.000 14.153 0 28  TRP AAA CH2 1 ? 
ATOM   227  N N   . VAL A 1 31  ? 2.048   -4.112 9.555  1.000 12.393 0 29  VAL AAA N   1 ? 
ATOM   228  C CA  . VAL A 1 31  ? 2.437   -4.668 10.886 1.000 12.384 0 29  VAL AAA CA  1 ? 
ATOM   229  C C   . VAL A 1 31  ? 3.899   -4.313 11.144 1.000 11.025 0 29  VAL AAA C   1 ? 
ATOM   230  O O   . VAL A 1 31  ? 4.206   -3.912 12.305 1.000 12.883 0 29  VAL AAA O   1 ? 
ATOM   231  C CB  . VAL A 1 31  ? 2.169   -6.177 10.971 1.000 14.148 0 29  VAL AAA CB  1 ? 
ATOM   232  C CG1 . VAL A 1 31  ? 2.734   -6.791 12.256 1.000 15.893 0 29  VAL AAA CG1 1 ? 
ATOM   233  C CG2 . VAL A 1 31  ? 0.667   -6.400 10.862 1.000 15.496 0 29  VAL AAA CG2 1 ? 
ATOM   234  N N   . GLN A 1 32  ? 4.786   -4.456 10.142 1.000 10.721 0 30  GLN AAA N   1 ? 
ATOM   235  C CA  . GLN A 1 32  ? 6.207   -4.104 10.303 1.000 11.288 0 30  GLN AAA CA  1 ? 
ATOM   236  C C   . GLN A 1 32  ? 6.332   -2.603 10.557 1.000 11.446 0 30  GLN AAA C   1 ? 
ATOM   237  O O   . GLN A 1 32  ? 7.096   -2.206 11.417 1.000 12.009 0 30  GLN AAA O   1 ? 
ATOM   238  C CB  . GLN A 1 32  ? 7.014   -4.572 9.087  1.000 12.457 0 30  GLN AAA CB  1 ? 
ATOM   239  C CG  . GLN A 1 32  ? 8.468   -4.127 9.072  1.000 12.270 0 30  GLN AAA CG  1 ? 
ATOM   240  C CD  . GLN A 1 32  ? 9.277   -4.546 10.285 1.000 12.676 0 30  GLN AAA CD  1 ? 
ATOM   241  O OE1 . GLN A 1 32  ? 9.074   -5.676 10.779 1.000 13.951 0 30  GLN AAA OE1 1 ? 
ATOM   242  N NE2 . GLN A 1 32  ? 10.188  -3.687 10.689 1.000 12.974 0 30  GLN AAA NE2 1 ? 
ATOM   243  N N   . ARG A 1 33  ? 5.687   -1.772 9.753  1.000 10.755 0 31  ARG AAA N   1 ? 
ATOM   244  C CA  . ARG A 1 33  ? 5.760   -0.306 9.968  1.000 10.802 0 31  ARG AAA CA  1 ? 
ATOM   245  C C   . ARG A 1 33  ? 5.350   0.016  11.405 1.000 10.821 0 31  ARG AAA C   1 ? 
ATOM   246  O O   . ARG A 1 33  ? 6.006   0.921  12.012 1.000 10.829 0 31  ARG AAA O   1 ? 
ATOM   247  C CB  . ARG A 1 33  ? 4.893   0.423  8.958  1.000 11.414 0 31  ARG AAA CB  1 ? 
ATOM   248  C CG  . ARG A 1 33  ? 4.874   1.954  9.110  1.000 11.745 0 31  ARG AAA CG  1 ? 
ATOM   249  C CD  . ARG A 1 33  ? 6.210   2.571  8.940  1.000 11.966 0 31  ARG AAA CD  1 ? 
ATOM   250  N NE  . ARG A 1 33  ? 6.140   4.042  9.131  1.000 11.367 0 31  ARG AAA NE  1 ? 
ATOM   251  C CZ  . ARG A 1 33  ? 7.044   4.901  8.683  1.000 12.999 0 31  ARG AAA CZ  1 ? 
ATOM   252  N NH1 . ARG A 1 33  ? 7.935   4.562  7.758  1.000 14.409 0 31  ARG AAA NH1 1 ? 
ATOM   253  N NH2 . ARG A 1 33  ? 6.974   6.164  9.078  1.000 13.486 0 31  ARG AAA NH2 1 ? 
ATOM   254  N N   . LEU A 1 34  ? 4.290   -0.584 11.908 1.000 10.005 0 32  LEU AAA N   1 ? 
ATOM   255  C CA  . LEU A 1 34  ? 3.827   -0.324 13.318 1.000 11.055 0 32  LEU AAA CA  1 ? 
ATOM   256  C C   . LEU A 1 34  ? 4.893   -0.743 14.323 1.000 12.559 0 32  LEU AAA C   1 ? 
ATOM   257  O O   . LEU A 1 34  ? 5.047   -0.012 15.345 1.000 12.758 0 32  LEU AAA O   1 ? 
ATOM   258  C CB  . LEU A 1 34  ? 2.515   -1.032 13.598 1.000 12.675 0 32  LEU AAA CB  1 ? 
ATOM   259  C CG  . LEU A 1 34  ? 1.294   -0.376 12.970 1.000 15.322 0 32  LEU AAA CG  1 ? 
ATOM   260  C CD1 . LEU A 1 34  ? 0.089   -1.285 13.077 1.000 17.221 0 32  LEU AAA CD1 1 ? 
ATOM   261  C CD2 . LEU A 1 34  ? 0.992   0.994  13.587 1.000 15.661 0 32  LEU AAA CD2 1 ? 
ATOM   262  N N   . LYS A 1 35  ? 5.667   -1.815 14.092 1.000 12.158 0 33  LYS AAA N   1 ? 
ATOM   263  C CA  . LYS A 1 35  ? 6.791   -2.138 14.997 1.000 12.217 0 33  LYS AAA CA  1 ? 
ATOM   264  C C   . LYS A 1 35  ? 7.784   -0.966 15.022 1.000 11.927 0 33  LYS AAA C   1 ? 
ATOM   265  O O   . LYS A 1 35  ? 8.259   -0.601 16.086 1.000 13.266 0 33  LYS AAA O   1 ? 
ATOM   266  C CB  . LYS A 1 35  ? 7.512   -3.433 14.623 1.000 12.787 0 33  LYS AAA CB  1 ? 
ATOM   267  C CG  . LYS A 1 35  ? 6.575   -4.626 14.685 1.000 15.034 0 33  LYS AAA CG  1 ? 
ATOM   268  C CD  . LYS A 1 35  ? 7.268   -5.913 14.394 1.000 16.091 0 33  LYS AAA CD  1 ? 
ATOM   269  C CE  . LYS A 1 35  ? 6.272   -7.070 14.418 1.000 18.341 0 33  LYS AAA CE  1 ? 
ATOM   270  N NZ  . LYS A 1 35  ? 6.853   -8.315 13.893 1.000 21.672 0 33  LYS AAA NZ  1 ? 
ATOM   271  N N   . GLU A 1 36  ? 8.108   -0.431 13.876 1.000 11.295 0 34  GLU AAA N   1 ? 
ATOM   272  C CA  . GLU A 1 36  ? 9.020   0.719  13.749 1.000 10.741 0 34  GLU AAA CA  1 ? 
ATOM   273  C C   . GLU A 1 36  ? 8.414   1.921  14.469 1.000 10.340 0 34  GLU AAA C   1 ? 
ATOM   274  O O   . GLU A 1 36  ? 9.179   2.667  15.144 1.000 10.361 0 34  GLU AAA O   1 ? 
ATOM   275  C CB  . GLU A 1 36  ? 9.322   1.009  12.276 1.000 11.726 0 34  GLU AAA CB  1 ? 
ATOM   276  C CG  . GLU A 1 36  ? 10.066  -0.117 11.568 1.000 12.427 0 34  GLU AAA CG  1 ? 
ATOM   277  C CD  . GLU A 1 36  ? 10.034  -0.038 10.052 1.000 14.513 0 34  GLU AAA CD  1 ? 
ATOM   278  O OE1 . GLU A 1 36  ? 9.701   1.054  9.526  1.000 15.036 0 34  GLU AAA OE1 1 ? 
ATOM   279  O OE2 . GLU A 1 36  ? 10.291  -1.081 9.415  1.000 14.830 0 34  GLU AAA OE2 1 ? 
ATOM   280  N N   . GLU A 1 37  ? 7.139   2.175  14.324 1.000 10.496 0 35  GLU AAA N   1 ? 
ATOM   281  C CA  . GLU A 1 37  ? 6.473   3.332  14.960 1.000 10.390 0 35  GLU AAA CA  1 ? 
ATOM   282  C C   . GLU A 1 37  ? 6.570   3.244  16.480 1.000 10.768 0 35  GLU AAA C   1 ? 
ATOM   283  O O   . GLU A 1 37  ? 6.907   4.218  17.131 1.000 10.450 0 35  GLU AAA O   1 ? 
ATOM   284  C CB  . GLU A 1 37  ? 5.011   3.414  14.550 1.000 11.913 0 35  GLU AAA CB  1 ? 
ATOM   285  C CG  . GLU A 1 37  ? 4.772   3.758  13.078 1.000 11.058 0 35  GLU AAA CG  1 ? 
ATOM   286  C CD  . GLU A 1 37  ? 5.117   5.171  12.634 1.000 12.197 0 35  GLU AAA CD  1 ? 
ATOM   287  O OE1 . GLU A 1 37  ? 5.442   6.016  13.497 1.000 12.589 0 35  GLU AAA OE1 1 ? 
ATOM   288  O OE2 . GLU A 1 37  ? 5.115   5.423  11.379 1.000 12.774 0 35  GLU AAA OE2 1 ? 
ATOM   289  N N   . TYR A 1 38  ? 6.292   2.082  17.014 1.000 10.881 0 36  TYR AAA N   1 ? 
ATOM   290  C CA  . TYR A 1 38  ? 6.294   1.864  18.487 1.000 10.948 0 36  TYR AAA CA  1 ? 
ATOM   291  C C   . TYR A 1 38  ? 7.748   1.944  18.942 1.000 12.309 0 36  TYR AAA C   1 ? 
ATOM   292  O O   . TYR A 1 38  ? 7.941   2.549  20.034 1.000 12.124 0 36  TYR AAA O   1 ? 
ATOM   293  C CB  . TYR A 1 38  ? 5.563   0.550  18.874 1.000 10.827 0 36  TYR AAA CB  1 ? 
ATOM   294  C CG  . TYR A 1 38  ? 4.062   0.699  19.047 1.000 11.699 0 36  TYR AAA CG  1 ? 
ATOM   295  C CD1 . TYR A 1 38  ? 3.146   0.383  18.051 1.000 12.336 0 36  TYR AAA CD1 1 ? 
ATOM   296  C CD2 . TYR A 1 38  ? 3.549   1.206  20.219 1.000 13.084 0 36  TYR AAA CD2 1 ? 
ATOM   297  C CE1 . TYR A 1 38  ? 1.776   0.553  18.224 1.000 13.143 0 36  TYR AAA CE1 1 ? 
ATOM   298  C CE2 . TYR A 1 38  ? 2.182   1.310  20.430 1.000 12.316 0 36  TYR AAA CE2 1 ? 
ATOM   299  C CZ  . TYR A 1 38  ? 1.282   1.001  19.430 1.000 13.580 0 36  TYR AAA CZ  1 ? 
ATOM   300  O OH  . TYR A 1 38  ? -0.078  1.120  19.627 1.000 16.078 0 36  TYR AAA OH  1 ? 
ATOM   301  N N   . GLN A 1 39  ? 8.721   1.334  18.277 1.000 11.452 0 37  GLN AAA N   1 ? 
ATOM   302  C CA  . GLN A 1 39  ? 10.123  1.411  18.719 1.000 12.824 0 37  GLN AAA CA  1 ? 
ATOM   303  C C   . GLN A 1 39  ? 10.591  2.877  18.728 1.000 11.725 0 37  GLN AAA C   1 ? 
ATOM   304  O O   . GLN A 1 39  ? 11.244  3.291  19.678 1.000 12.490 0 37  GLN AAA O   1 ? 
ATOM   305  C CB  . GLN A 1 39  ? 11.002  0.417  17.969 1.000 16.378 0 37  GLN AAA CB  1 ? 
ATOM   306  C CG  . GLN A 1 39  ? 11.808  0.914  16.809 1.000 20.274 0 37  GLN AAA CG  1 ? 
ATOM   307  C CD  . GLN A 1 39  ? 12.667  -0.094 16.077 1.000 18.990 0 37  GLN AAA CD  1 ? 
ATOM   308  O OE1 . GLN A 1 39  ? 13.035  -1.201 16.557 1.000 20.450 0 37  GLN AAA OE1 1 ? 
ATOM   309  N NE2 . GLN A 1 39  ? 12.937  0.237  14.823 1.000 19.262 0 37  GLN AAA NE2 1 ? 
ATOM   310  N N   A SER A 1 40  ? 10.201  3.678  17.742 0.500 12.061 0 38  SER AAA N   1 ? 
ATOM   311  N N   B SER A 1 40  ? 10.196  3.684  17.751 0.500 10.735 0 38  SER AAA N   1 ? 
ATOM   312  C CA  A SER A 1 40  ? 10.622  5.096  17.643 0.500 12.205 0 38  SER AAA CA  1 ? 
ATOM   313  C CA  B SER A 1 40  ? 10.634  5.096  17.670 0.500 10.114 0 38  SER AAA CA  1 ? 
ATOM   314  C C   A SER A 1 40  ? 9.907   5.902  18.747 0.500 11.892 0 38  SER AAA C   1 ? 
ATOM   315  C C   B SER A 1 40  ? 9.908   5.903  18.764 0.500 10.658 0 38  SER AAA C   1 ? 
ATOM   316  O O   A SER A 1 40  ? 10.549  6.723  19.426 0.500 12.124 0 38  SER AAA O   1 ? 
ATOM   317  O O   B SER A 1 40  ? 10.532  6.745  19.434 0.500 10.872 0 38  SER AAA O   1 ? 
ATOM   318  C CB  A SER A 1 40  ? 10.362  5.628  16.250 0.500 12.612 0 38  SER AAA CB  1 ? 
ATOM   319  C CB  B SER A 1 40  ? 10.398  5.646  16.291 0.500 9.250  0 38  SER AAA CB  1 ? 
ATOM   320  O OG  A SER A 1 40  ? 10.806  6.972  16.116 0.500 15.119 0 38  SER AAA OG  1 ? 
ATOM   321  O OG  B SER A 1 40  ? 11.295  5.059  15.363 0.500 8.414  0 38  SER AAA OG  1 ? 
ATOM   322  N N   . LEU A 1 41  ? 8.598   5.698  18.926 1.000 11.319 0 39  LEU AAA N   1 ? 
ATOM   323  C CA  . LEU A 1 41  ? 7.848   6.411  19.966 1.000 11.187 0 39  LEU AAA CA  1 ? 
ATOM   324  C C   . LEU A 1 41  ? 8.393   6.113  21.346 1.000 12.035 0 39  LEU AAA C   1 ? 
ATOM   325  O O   . LEU A 1 41  ? 8.544   7.063  22.129 1.000 12.501 0 39  LEU AAA O   1 ? 
ATOM   326  C CB  . LEU A 1 41  ? 6.357   6.087  19.907 1.000 13.153 0 39  LEU AAA CB  1 ? 
ATOM   327  C CG  . LEU A 1 41  ? 5.557   6.824  18.852 1.000 14.757 0 39  LEU AAA CG  1 ? 
ATOM   328  C CD1 . LEU A 1 41  ? 4.221   6.148  18.658 1.000 16.124 0 39  LEU AAA CD1 1 ? 
ATOM   329  C CD2 . LEU A 1 41  ? 5.388   8.295  19.289 1.000 14.081 0 39  LEU AAA CD2 1 ? 
ATOM   330  N N   . ILE A 1 42  ? 8.641   4.846  21.704 1.000 11.270 0 40  ILE AAA N   1 ? 
ATOM   331  C CA  . ILE A 1 42  ? 9.004   4.586  23.122 1.000 11.458 0 40  ILE AAA CA  1 ? 
ATOM   332  C C   . ILE A 1 42  ? 10.416  5.125  23.342 1.000 12.218 0 40  ILE AAA C   1 ? 
ATOM   333  O O   . ILE A 1 42  ? 10.691  5.552  24.487 1.000 12.870 0 40  ILE AAA O   1 ? 
ATOM   334  C CB  . ILE A 1 42  ? 8.788   3.103  23.484 1.000 11.857 0 40  ILE AAA CB  1 ? 
ATOM   335  C CG1 . ILE A 1 42  ? 8.639   2.922  25.000 1.000 13.256 0 40  ILE AAA CG1 1 ? 
ATOM   336  C CG2 . ILE A 1 42  ? 9.825   2.201  22.881 1.000 13.576 0 40  ILE AAA CG2 1 ? 
ATOM   337  C CD1 . ILE A 1 42  ? 7.493   3.658  25.620 1.000 16.098 0 40  ILE AAA CD1 1 ? 
ATOM   338  N N   . ARG A 1 43  ? 11.319  5.057  22.376 1.000 12.850 0 41  ARG AAA N   1 ? 
ATOM   339  C CA  . ARG A 1 43  ? 12.681  5.636  22.579 1.000 13.042 0 41  ARG AAA CA  1 ? 
ATOM   340  C C   . ARG A 1 43  ? 12.539  7.161  22.816 1.000 13.062 0 41  ARG AAA C   1 ? 
ATOM   341  O O   . ARG A 1 43  ? 13.166  7.709  23.726 1.000 12.858 0 41  ARG AAA O   1 ? 
ATOM   342  C CB  . ARG A 1 43  ? 13.638  5.271  21.444 1.000 13.737 0 41  ARG AAA CB  1 ? 
ATOM   343  C CG  . ARG A 1 43  ? 14.977  5.994  21.548 1.000 14.393 0 41  ARG AAA CG  1 ? 
ATOM   344  C CD  . ARG A 1 43  ? 15.851  5.542  22.725 1.000 18.580 0 41  ARG AAA CD  1 ? 
ATOM   345  N NE  . ARG A 1 43  ? 16.992  6.485  22.824 1.000 21.560 0 41  ARG AAA NE  1 ? 
ATOM   346  C CZ  . ARG A 1 43  ? 18.169  6.468  22.150 1.000 27.220 0 41  ARG AAA CZ  1 ? 
ATOM   347  N NH1 . ARG A 1 43  ? 19.053  7.415  22.397 1.000 34.573 0 41  ARG AAA NH1 1 ? 
ATOM   348  N NH2 . ARG A 1 43  ? 18.536  5.449  21.386 1.000 26.099 0 41  ARG AAA NH2 1 ? 
ATOM   349  N N   . TYR A 1 44  ? 11.685  7.829  22.057 1.000 12.000 0 42  TYR AAA N   1 ? 
ATOM   350  C CA  . TYR A 1 44  ? 11.448  9.283  22.211 1.000 12.695 0 42  TYR AAA CA  1 ? 
ATOM   351  C C   . TYR A 1 44  ? 10.908  9.568  23.611 1.000 13.221 0 42  TYR AAA C   1 ? 
ATOM   352  O O   . TYR A 1 44  ? 11.412  10.450 24.289 1.000 12.289 0 42  TYR AAA O   1 ? 
ATOM   353  C CB  . TYR A 1 44  ? 10.583  9.774  21.047 1.000 11.268 0 42  TYR AAA CB  1 ? 
ATOM   354  C CG  . TYR A 1 44  ? 10.287  11.255 21.083 1.000 11.200 0 42  TYR AAA CG  1 ? 
ATOM   355  C CD1 . TYR A 1 44  ? 11.263  12.198 21.341 1.000 12.330 0 42  TYR AAA CD1 1 ? 
ATOM   356  C CD2 . TYR A 1 44  ? 9.023   11.735 20.836 1.000 11.508 0 42  TYR AAA CD2 1 ? 
ATOM   357  C CE1 . TYR A 1 44  ? 10.985  13.550 21.354 1.000 12.008 0 42  TYR AAA CE1 1 ? 
ATOM   358  C CE2 . TYR A 1 44  ? 8.712   13.073 20.876 1.000 12.390 0 42  TYR AAA CE2 1 ? 
ATOM   359  C CZ  . TYR A 1 44  ? 9.706   14.002 21.136 1.000 12.007 0 42  TYR AAA CZ  1 ? 
ATOM   360  O OH  . TYR A 1 44  ? 9.470   15.362 21.207 1.000 13.005 0 42  TYR AAA OH  1 ? 
ATOM   361  N N   . VAL A 1 45  ? 9.913   8.801  24.077 1.000 11.741 0 43  VAL AAA N   1 ? 
ATOM   362  C CA  . VAL A 1 45  ? 9.365   8.951  25.463 1.000 12.134 0 43  VAL AAA CA  1 ? 
ATOM   363  C C   . VAL A 1 45  ? 10.485  8.791  26.475 1.000 13.997 0 43  VAL AAA C   1 ? 
ATOM   364  O O   . VAL A 1 45  ? 10.535  9.636  27.422 1.000 14.808 0 43  VAL AAA O   1 ? 
ATOM   365  C CB  . VAL A 1 45  ? 8.189   7.995  25.687 1.000 12.403 0 43  VAL AAA CB  1 ? 
ATOM   366  C CG1 . VAL A 1 45  ? 7.802   8.031  27.172 1.000 13.436 0 43  VAL AAA CG1 1 ? 
ATOM   367  C CG2 . VAL A 1 45  ? 7.001   8.370  24.879 1.000 13.644 0 43  VAL AAA CG2 1 ? 
ATOM   368  N N   . GLU A 1 46  ? 11.300  7.769  26.344 1.000 13.212 0 44  GLU AAA N   1 ? 
ATOM   369  C CA  . GLU A 1 46  ? 12.364  7.500  27.345 1.000 14.882 0 44  GLU AAA CA  1 ? 
ATOM   370  C C   . GLU A 1 46  ? 13.386  8.644  27.332 1.000 14.697 0 44  GLU AAA C   1 ? 
ATOM   371  O O   . GLU A 1 46  ? 13.759  9.124  28.415 1.000 14.497 0 44  GLU AAA O   1 ? 
ATOM   372  C CB  . GLU A 1 46  ? 12.968  6.139  27.066 1.000 18.241 0 44  GLU AAA CB  1 ? 
ATOM   373  C CG  . GLU A 1 46  ? 11.963  5.030  27.401 1.000 22.481 0 44  GLU AAA CG  1 ? 
ATOM   374  C CD  . GLU A 1 46  ? 12.225  3.613  26.882 1.000 26.779 0 44  GLU AAA CD  1 ? 
ATOM   375  O OE1 . GLU A 1 46  ? 11.499  2.723  27.363 1.000 33.921 0 44  GLU AAA OE1 1 ? 
ATOM   376  O OE2 . GLU A 1 46  ? 13.090  3.409  25.962 1.000 32.622 0 44  GLU AAA OE2 1 ? 
ATOM   377  N N   . ASN A 1 47  ? 13.796  9.096  26.164 1.000 13.723 0 45  ASN AAA N   1 ? 
ATOM   378  C CA  . ASN A 1 47  ? 14.676  10.287 26.041 1.000 14.644 0 45  ASN AAA CA  1 ? 
ATOM   379  C C   . ASN A 1 47  ? 14.007  11.477 26.754 1.000 13.489 0 45  ASN AAA C   1 ? 
ATOM   380  O O   . ASN A 1 47  ? 14.667  12.308 27.463 1.000 13.712 0 45  ASN AAA O   1 ? 
ATOM   381  C CB  . ASN A 1 47  ? 14.953  10.607 24.578 1.000 14.689 0 45  ASN AAA CB  1 ? 
ATOM   382  C CG  . ASN A 1 47  ? 15.814  9.587  23.881 1.000 16.999 0 45  ASN AAA CG  1 ? 
ATOM   383  O OD1 . ASN A 1 47  ? 16.374  8.692  24.508 1.000 19.523 0 45  ASN AAA OD1 1 ? 
ATOM   384  N ND2 . ASN A 1 47  ? 15.847  9.724  22.568 1.000 17.953 0 45  ASN AAA ND2 1 ? 
ATOM   385  N N   . ASN A 1 48  ? 12.734  11.670 26.524 1.000 12.610 0 46  ASN AAA N   1 ? 
ATOM   386  C CA  . ASN A 1 48  ? 12.001  12.815 27.099 1.000 12.066 0 46  ASN AAA CA  1 ? 
ATOM   387  C C   . ASN A 1 48  ? 12.039  12.748 28.623 1.000 13.327 0 46  ASN AAA C   1 ? 
ATOM   388  O O   . ASN A 1 48  ? 12.214  13.792 29.300 1.000 14.358 0 46  ASN AAA O   1 ? 
ATOM   389  C CB  . ASN A 1 48  ? 10.556  12.881 26.599 1.000 13.047 0 46  ASN AAA CB  1 ? 
ATOM   390  C CG  . ASN A 1 48  ? 10.432  13.298 25.141 1.000 13.466 0 46  ASN AAA CG  1 ? 
ATOM   391  O OD1 . ASN A 1 48  ? 11.340  13.886 24.607 1.000 15.153 0 46  ASN AAA OD1 1 ? 
ATOM   392  N ND2 . ASN A 1 48  ? 9.276   13.033 24.576 1.000 13.030 0 46  ASN AAA ND2 1 ? 
ATOM   393  N N   . LYS A 1 49  ? 11.783  11.578 29.184 1.000 13.572 0 47  LYS AAA N   1 ? 
ATOM   394  C CA  . LYS A 1 49  ? 11.850  11.421 30.669 1.000 14.724 0 47  LYS AAA CA  1 ? 
ATOM   395  C C   . LYS A 1 49  ? 13.235  11.797 31.169 1.000 16.099 0 47  LYS AAA C   1 ? 
ATOM   396  O O   . LYS A 1 49  ? 13.320  12.446 32.243 1.000 17.846 0 47  LYS AAA O   1 ? 
ATOM   397  C CB  . LYS A 1 49  ? 11.521  9.975  31.018 1.000 16.599 0 47  LYS AAA CB  1 ? 
ATOM   398  C CG  . LYS A 1 49  ? 10.066  9.635  30.893 1.000 19.031 0 47  LYS AAA CG  1 ? 
ATOM   399  C CD  . LYS A 1 49  ? 9.842   8.133  31.142 1.000 24.830 0 47  LYS AAA CD  1 ? 
ATOM   400  C CE  . LYS A 1 49  ? 8.392   7.725  31.085 1.000 29.537 0 47  LYS AAA CE  1 ? 
ATOM   401  N NZ  . LYS A 1 49  ? 8.216   6.336  31.593 1.000 34.296 0 47  LYS AAA NZ  1 ? 
ATOM   402  N N   . ASN A 1 50  ? 14.301  11.337 30.520 1.000 16.834 0 48  ASN AAA N   1 ? 
ATOM   403  C CA  . ASN A 1 50  ? 15.688  11.629 30.938 1.000 18.719 0 48  ASN AAA CA  1 ? 
ATOM   404  C C   . ASN A 1 50  ? 15.931  13.138 30.867 1.000 18.452 0 48  ASN AAA C   1 ? 
ATOM   405  O O   . ASN A 1 50  ? 16.826  13.646 31.588 1.000 22.560 0 48  ASN AAA O   1 ? 
ATOM   406  C CB  . ASN A 1 50  ? 16.663  10.834 30.080 1.000 23.540 0 48  ASN AAA CB  1 ? 
ATOM   407  C CG  . ASN A 1 50  ? 16.633  9.380  30.475 1.000 31.122 0 48  ASN AAA CG  1 ? 
ATOM   408  O OD1 . ASN A 1 50  ? 16.348  9.065  31.631 1.000 42.623 0 48  ASN AAA OD1 1 ? 
ATOM   409  N ND2 . ASN A 1 50  ? 16.962  8.508  29.537 1.000 39.936 0 48  ASN AAA ND2 1 ? 
ATOM   410  N N   . ALA A 1 51  ? 15.214  13.867 30.010 1.000 16.055 0 49  ALA AAA N   1 ? 
ATOM   411  C CA  . ALA A 1 51  ? 15.386  15.332 29.825 1.000 15.227 0 49  ALA AAA CA  1 ? 
ATOM   412  C C   . ALA A 1 51  ? 14.399  16.146 30.669 1.000 15.243 0 49  ALA AAA C   1 ? 
ATOM   413  O O   . ALA A 1 51  ? 14.251  17.351 30.385 1.000 15.551 0 49  ALA AAA O   1 ? 
ATOM   414  C CB  . ALA A 1 51  ? 15.185  15.644 28.373 1.000 17.875 0 49  ALA AAA CB  1 ? 
ATOM   415  N N   . ASP A 1 52  ? 13.657  15.551 31.616 1.000 14.909 0 50  ASP AAA N   1 ? 
ATOM   416  C CA  . ASP A 1 52  ? 12.583  16.233 32.357 1.000 16.423 0 50  ASP AAA CA  1 ? 
ATOM   417  C C   . ASP A 1 52  ? 11.610  16.948 31.421 1.000 13.567 0 50  ASP AAA C   1 ? 
ATOM   418  O O   . ASP A 1 52  ? 11.036  18.022 31.736 1.000 15.269 0 50  ASP AAA O   1 ? 
ATOM   419  C CB  . ASP A 1 52  ? 13.176  17.189 33.405 1.000 16.698 0 50  ASP AAA CB  1 ? 
ATOM   420  C CG  . ASP A 1 52  ? 12.149  17.716 34.395 1.000 21.159 0 50  ASP AAA CG  1 ? 
ATOM   421  O OD1 . ASP A 1 52  ? 11.259  16.937 34.807 1.000 24.121 0 50  ASP AAA OD1 1 ? 
ATOM   422  O OD2 . ASP A 1 52  ? 12.190  18.924 34.698 1.000 23.704 0 50  ASP AAA OD2 1 ? 
ATOM   423  N N   . ASN A 1 53  ? 11.261  16.277 30.301 1.000 14.056 0 51  ASN AAA N   1 ? 
ATOM   424  C CA  . ASN A 1 53  ? 10.314  16.835 29.318 1.000 14.714 0 51  ASN AAA CA  1 ? 
ATOM   425  C C   . ASN A 1 53  ? 9.389   15.708 28.848 1.000 14.092 0 51  ASN AAA C   1 ? 
ATOM   426  O O   . ASN A 1 53  ? 9.121   15.599 27.633 1.000 12.908 0 51  ASN AAA O   1 ? 
ATOM   427  C CB  . ASN A 1 53  ? 11.009  17.505 28.137 1.000 13.682 0 51  ASN AAA CB  1 ? 
ATOM   428  C CG  . ASN A 1 53  ? 10.013  18.347 27.383 1.000 15.777 0 51  ASN AAA CG  1 ? 
ATOM   429  O OD1 . ASN A 1 53  ? 9.239   19.097 27.980 1.000 20.561 0 51  ASN AAA OD1 1 ? 
ATOM   430  N ND2 . ASN A 1 53  ? 10.004  18.281 26.074 1.000 13.902 0 51  ASN AAA ND2 1 ? 
ATOM   431  N N   . ASP A 1 54  ? 8.836   14.954 29.784 1.000 14.647 0 52  ASP AAA N   1 ? 
ATOM   432  C CA  . ASP A 1 54  ? 7.891   13.862 29.434 1.000 15.149 0 52  ASP AAA CA  1 ? 
ATOM   433  C C   . ASP A 1 54  ? 6.527   14.453 29.144 1.000 15.134 0 52  ASP AAA C   1 ? 
ATOM   434  O O   . ASP A 1 54  ? 5.711   14.553 30.016 1.000 18.879 0 52  ASP AAA O   1 ? 
ATOM   435  C CB  . ASP A 1 54  ? 7.929   12.788 30.524 1.000 15.249 0 52  ASP AAA CB  1 ? 
ATOM   436  C CG  . ASP A 1 54  ? 7.149   11.534 30.199 1.000 19.540 0 52  ASP AAA CG  1 ? 
ATOM   437  O OD1 . ASP A 1 54  ? 6.838   11.326 29.034 1.000 17.731 0 52  ASP AAA OD1 1 ? 
ATOM   438  O OD2 . ASP A 1 54  ? 6.843   10.787 31.183 1.000 20.425 0 52  ASP AAA OD2 1 ? 
ATOM   439  N N   . TRP A 1 55  ? 6.247   14.785 27.887 1.000 11.544 0 53  TRP AAA N   1 ? 
ATOM   440  C CA  . TRP A 1 55  ? 5.191   15.742 27.527 1.000 12.758 0 53  TRP AAA CA  1 ? 
ATOM   441  C C   . TRP A 1 55  ? 4.012   15.080 26.794 1.000 12.242 0 53  TRP AAA C   1 ? 
ATOM   442  O O   . TRP A 1 55  ? 3.082   15.769 26.486 1.000 13.154 0 53  TRP AAA O   1 ? 
ATOM   443  C CB  . TRP A 1 55  ? 5.779   16.905 26.707 1.000 11.529 0 53  TRP AAA CB  1 ? 
ATOM   444  C CG  . TRP A 1 55  ? 6.244   16.585 25.311 1.000 11.665 0 53  TRP AAA CG  1 ? 
ATOM   445  C CD1 . TRP A 1 55  ? 7.478   16.123 24.952 1.000 10.704 0 53  TRP AAA CD1 1 ? 
ATOM   446  C CD2 . TRP A 1 55  ? 5.498   16.725 24.091 1.000 11.825 0 53  TRP AAA CD2 1 ? 
ATOM   447  N NE1 . TRP A 1 55  ? 7.569   15.976 23.588 1.000 12.443 0 53  TRP AAA NE1 1 ? 
ATOM   448  C CE2 . TRP A 1 55  ? 6.373   16.367 23.059 1.000 10.213 0 53  TRP AAA CE2 1 ? 
ATOM   449  C CE3 . TRP A 1 55  ? 4.200   17.171 23.786 1.000 12.025 0 53  TRP AAA CE3 1 ? 
ATOM   450  C CZ2 . TRP A 1 55  ? 5.995   16.430 21.724 1.000 11.896 0 53  TRP AAA CZ2 1 ? 
ATOM   451  C CZ3 . TRP A 1 55  ? 3.829   17.221 22.467 1.000 12.029 0 53  TRP AAA CZ3 1 ? 
ATOM   452  C CH2 . TRP A 1 55  ? 4.697   16.818 21.467 1.000 12.565 0 53  TRP AAA CH2 1 ? 
ATOM   453  N N   . PHE A 1 56  ? 4.020   13.755 26.561 1.000 13.855 0 54  PHE AAA N   1 ? 
ATOM   454  C CA  . PHE A 1 56  ? 2.846   13.121 25.909 1.000 13.536 0 54  PHE AAA CA  1 ? 
ATOM   455  C C   . PHE A 1 56  ? 2.782   11.633 26.242 1.000 13.262 0 54  PHE AAA C   1 ? 
ATOM   456  O O   . PHE A 1 56  ? 3.820   11.003 26.518 1.000 14.537 0 54  PHE AAA O   1 ? 
ATOM   457  C CB  . PHE A 1 56  ? 2.879   13.349 24.383 1.000 13.184 0 54  PHE AAA CB  1 ? 
ATOM   458  C CG  . PHE A 1 56  ? 3.859   12.483 23.649 1.000 13.670 0 54  PHE AAA CG  1 ? 
ATOM   459  C CD1 . PHE A 1 56  ? 3.466   11.221 23.195 1.000 14.148 0 54  PHE AAA CD1 1 ? 
ATOM   460  C CD2 . PHE A 1 56  ? 5.190   12.845 23.487 1.000 14.116 0 54  PHE AAA CD2 1 ? 
ATOM   461  C CE1 . PHE A 1 56  ? 4.354   10.364 22.570 1.000 14.989 0 54  PHE AAA CE1 1 ? 
ATOM   462  C CE2 . PHE A 1 56  ? 6.077   11.946 22.917 1.000 15.694 0 54  PHE AAA CE2 1 ? 
ATOM   463  C CZ  . PHE A 1 56  ? 5.662   10.714 22.432 1.000 14.308 0 54  PHE AAA CZ  1 ? 
ATOM   464  N N   . ARG A 1 57  ? 1.577   11.082 26.063 1.000 13.934 0 55  ARG AAA N   1 ? 
ATOM   465  C CA  . ARG A 1 57  ? 1.316   9.605  25.987 1.000 16.493 0 55  ARG AAA CA  1 ? 
ATOM   466  C C   . ARG A 1 57  ? 0.461   9.365  24.733 1.000 16.149 0 55  ARG AAA C   1 ? 
ATOM   467  O O   . ARG A 1 57  ? -0.472  10.145 24.495 1.000 15.614 0 55  ARG AAA O   1 ? 
ATOM   468  C CB  . ARG A 1 57  ? 0.616   9.138  27.268 1.000 17.663 0 55  ARG AAA CB  1 ? 
ATOM   469  C CG  . ARG A 1 57  ? 1.563   9.043  28.459 1.000 19.052 0 55  ARG AAA CG  1 ? 
ATOM   470  C CD  . ARG A 1 57  ? 2.596   7.937  28.353 1.000 21.165 0 55  ARG AAA CD  1 ? 
ATOM   471  N NE  . ARG A 1 57  ? 3.435   7.855  29.553 1.000 24.174 0 55  ARG AAA NE  1 ? 
ATOM   472  C CZ  . ARG A 1 57  ? 4.507   8.621  29.706 1.000 25.863 0 55  ARG AAA CZ  1 ? 
ATOM   473  N NH1 . ARG A 1 57  ? 4.786   9.491  28.759 1.000 19.434 0 55  ARG AAA NH1 1 ? 
ATOM   474  N NH2 . ARG A 1 57  ? 5.267   8.555  30.797 1.000 25.403 0 55  ARG AAA NH2 1 ? 
ATOM   475  N N   . LEU A 1 58  ? 0.694   8.272  24.042 1.000 16.305 0 56  LEU AAA N   1 ? 
ATOM   476  C CA  . LEU A 1 58  ? -0.177  7.888  22.898 1.000 15.149 0 56  LEU AAA CA  1 ? 
ATOM   477  C C   . LEU A 1 58  ? -0.490  6.402  22.985 1.000 15.212 0 56  LEU AAA C   1 ? 
ATOM   478  O O   . LEU A 1 58  ? 0.390   5.625  23.391 1.000 16.555 0 56  LEU AAA O   1 ? 
ATOM   479  C CB  . LEU A 1 58  ? 0.502   8.194  21.577 1.000 16.043 0 56  LEU AAA CB  1 ? 
ATOM   480  C CG  . LEU A 1 58  ? 0.396   9.631  21.101 1.000 17.632 0 56  LEU AAA CG  1 ? 
ATOM   481  C CD1 . LEU A 1 58  ? 1.362   9.847  19.954 1.000 18.217 0 56  LEU AAA CD1 1 ? 
ATOM   482  C CD2 . LEU A 1 58  ? -1.050  9.965  20.703 1.000 16.161 0 56  LEU AAA CD2 1 ? 
ATOM   483  N N   . GLU A 1 59  ? -1.696  6.050  22.554 1.000 16.332 0 57  GLU AAA N   1 ? 
ATOM   484  C CA  . GLU A 1 59  ? -2.120  4.654  22.334 1.000 18.072 0 57  GLU AAA CA  1 ? 
ATOM   485  C C   . GLU A 1 59  ? -2.783  4.589  20.962 1.000 15.936 0 57  GLU AAA C   1 ? 
ATOM   486  O O   . GLU A 1 59  ? -3.208  5.631  20.428 1.000 15.560 0 57  GLU AAA O   1 ? 
ATOM   487  C CB  . GLU A 1 59  ? -2.996  4.159  23.469 1.000 20.349 0 57  GLU AAA CB  1 ? 
ATOM   488  C CG  . GLU A 1 59  ? -4.373  4.748  23.564 1.000 24.362 0 57  GLU AAA CG  1 ? 
ATOM   489  C CD  . GLU A 1 59  ? -5.007  4.098  24.791 1.000 28.420 0 57  GLU AAA CD  1 ? 
ATOM   490  O OE1 . GLU A 1 59  ? -5.461  2.930  24.687 1.000 29.552 0 57  GLU AAA OE1 1 ? 
ATOM   491  O OE2 . GLU A 1 59  ? -4.832  4.659  25.863 1.000 34.355 0 57  GLU AAA OE2 1 ? 
ATOM   492  N N   . SER A 1 60  ? -2.870  3.385  20.429 1.000 15.169 0 58  SER AAA N   1 ? 
ATOM   493  C CA  . SER A 1 60  ? -3.608  3.148  19.176 1.000 13.599 0 58  SER AAA CA  1 ? 
ATOM   494  C C   . SER A 1 60  ? -4.678  2.100  19.415 1.000 13.127 0 58  SER AAA C   1 ? 
ATOM   495  O O   . SER A 1 60  ? -4.631  1.307  20.386 1.000 14.003 0 58  SER AAA O   1 ? 
ATOM   496  C CB  . SER A 1 60  ? -2.719  2.756  18.030 1.000 14.348 0 58  SER AAA CB  1 ? 
ATOM   497  O OG  . SER A 1 60  ? -2.243  1.425  18.113 1.000 15.316 0 58  SER AAA OG  1 ? 
ATOM   498  N N   . ASN A 1 61  ? -5.556  2.049  18.444 1.000 13.174 0 59  ASN AAA N   1 ? 
ATOM   499  C CA  . ASN A 1 61  ? -6.499  0.922  18.333 1.000 13.846 0 59  ASN AAA CA  1 ? 
ATOM   500  C C   . ASN A 1 61  ? -5.736  -0.333 17.896 1.000 15.054 0 59  ASN AAA C   1 ? 
ATOM   501  O O   . ASN A 1 61  ? -4.516  -0.337 17.665 1.000 14.629 0 59  ASN AAA O   1 ? 
ATOM   502  C CB  . ASN A 1 61  ? -7.669  1.293  17.423 1.000 13.869 0 59  ASN AAA CB  1 ? 
ATOM   503  C CG  . ASN A 1 61  ? -7.268  1.536  15.981 1.000 14.755 0 59  ASN AAA CG  1 ? 
ATOM   504  O OD1 . ASN A 1 61  ? -6.075  1.559  15.605 1.000 13.604 0 59  ASN AAA OD1 1 ? 
ATOM   505  N ND2 . ASN A 1 61  ? -8.285  1.768  15.158 1.000 15.959 0 59  ASN AAA ND2 1 ? 
ATOM   506  N N   . LYS A 1 62  ? -6.429  -1.474 17.780 1.000 15.248 0 60  LYS AAA N   1 ? 
ATOM   507  C CA  . LYS A 1 62  ? -5.687  -2.735 17.519 1.000 17.471 0 60  LYS AAA CA  1 ? 
ATOM   508  C C   . LYS A 1 62  ? -4.958  -2.672 16.171 1.000 17.749 0 60  LYS AAA C   1 ? 
ATOM   509  O O   . LYS A 1 62  ? -3.782  -3.093 16.064 1.000 20.088 0 60  LYS AAA O   1 ? 
ATOM   510  C CB  . LYS A 1 62  ? -6.650  -3.933 17.515 1.000 20.039 0 60  LYS AAA CB  1 ? 
ATOM   511  C CG  . LYS A 1 62  ? -5.918  -5.257 17.298 1.000 25.680 0 60  LYS AAA CG  1 ? 
ATOM   512  N N   . GLU A 1 63  ? -5.575  -2.083 15.159 1.000 16.118 0 61  GLU AAA N   1 ? 
ATOM   513  C CA  . GLU A 1 63  ? -5.032  -2.087 13.790 1.000 17.788 0 61  GLU AAA CA  1 ? 
ATOM   514  C C   . GLU A 1 63  ? -4.015  -0.942 13.600 1.000 18.210 0 61  GLU AAA C   1 ? 
ATOM   515  O O   . GLU A 1 63  ? -3.362  -0.916 12.555 1.000 19.927 0 61  GLU AAA O   1 ? 
ATOM   516  C CB  . GLU A 1 63  ? -6.148  -1.993 12.757 1.000 20.367 0 61  GLU AAA CB  1 ? 
ATOM   517  C CG  . GLU A 1 63  ? -7.080  -3.187 12.766 1.000 21.973 0 61  GLU AAA CG  1 ? 
ATOM   518  C CD  . GLU A 1 63  ? -8.045  -3.279 11.589 1.000 32.850 0 61  GLU AAA CD  1 ? 
ATOM   519  O OE1 . GLU A 1 63  ? -8.894  -2.350 11.363 1.000 36.998 0 61  GLU AAA OE1 1 ? 
ATOM   520  N N   . GLY A 1 64  ? -3.863  -0.054 14.579 1.000 15.681 0 62  GLY AAA N   1 ? 
ATOM   521  C CA  . GLY A 1 64  ? -2.895  1.059  14.532 1.000 17.104 0 62  GLY AAA CA  1 ? 
ATOM   522  C C   . GLY A 1 64  ? -3.331  2.202  13.591 1.000 16.989 0 62  GLY AAA C   1 ? 
ATOM   523  O O   . GLY A 1 64  ? -2.405  2.962  13.152 1.000 17.181 0 62  GLY AAA O   1 ? 
ATOM   524  N N   . THR A 1 65  ? -4.621  2.318  13.269 1.000 16.719 0 63  THR AAA N   1 ? 
ATOM   525  C CA  . THR A 1 65  ? -5.204  3.307  12.334 1.000 17.182 0 63  THR AAA CA  1 ? 
ATOM   526  C C   . THR A 1 65  ? -5.771  4.529  13.038 1.000 16.435 0 63  THR AAA C   1 ? 
ATOM   527  O O   . THR A 1 65  ? -5.943  5.566  12.392 1.000 17.009 0 63  THR AAA O   1 ? 
ATOM   528  C CB  . THR A 1 65  ? -6.282  2.647  11.484 1.000 19.367 0 63  THR AAA CB  1 ? 
ATOM   529  O OG1 . THR A 1 65  ? -7.340  2.144  12.295 1.000 17.501 0 63  THR AAA OG1 1 ? 
ATOM   530  C CG2 . THR A 1 65  ? -5.673  1.533  10.659 1.000 21.005 0 63  THR AAA CG2 1 ? 
ATOM   531  N N   . ARG A 1 66  ? -6.060  4.403  14.314 1.000 13.765 0 64  ARG AAA N   1 ? 
ATOM   532  C CA  . ARG A 1 66  ? -6.547  5.517  15.139 1.000 14.427 0 64  ARG AAA CA  1 ? 
ATOM   533  C C   . ARG A 1 66  ? -5.676  5.629  16.375 1.000 12.872 0 64  ARG AAA C   1 ? 
ATOM   534  O O   . ARG A 1 66  ? -5.482  4.618  17.068 1.000 13.832 0 64  ARG AAA O   1 ? 
ATOM   535  C CB  . ARG A 1 66  ? -7.999  5.284  15.536 1.000 15.977 0 64  ARG AAA CB  1 ? 
ATOM   536  C CG  . ARG A 1 66  ? -8.913  5.114  14.338 1.000 21.010 0 64  ARG AAA CG  1 ? 
ATOM   537  N N   . TRP A 1 67  ? -5.115  6.823  16.586 1.000 11.853 0 65  TRP AAA N   1 ? 
ATOM   538  C CA  . TRP A 1 67  ? -4.238  7.136  17.728 1.000 12.732 0 65  TRP AAA CA  1 ? 
ATOM   539  C C   . TRP A 1 67  ? -4.890  8.174  18.619 1.000 13.136 0 65  TRP AAA C   1 ? 
ATOM   540  O O   . TRP A 1 67  ? -5.593  9.061  18.135 1.000 13.382 0 65  TRP AAA O   1 ? 
ATOM   541  C CB  . TRP A 1 67  ? -2.865  7.597  17.208 1.000 12.034 0 65  TRP AAA CB  1 ? 
ATOM   542  C CG  . TRP A 1 67  ? -2.109  6.517  16.524 1.000 11.715 0 65  TRP AAA CG  1 ? 
ATOM   543  C CD1 . TRP A 1 67  ? -2.369  5.995  15.285 1.000 12.814 0 65  TRP AAA CD1 1 ? 
ATOM   544  C CD2 . TRP A 1 67  ? -1.017  5.748  17.077 1.000 12.553 0 65  TRP AAA CD2 1 ? 
ATOM   545  N NE1 . TRP A 1 67  ? -1.479  4.974  15.039 1.000 13.493 0 65  TRP AAA NE1 1 ? 
ATOM   546  C CE2 . TRP A 1 67  ? -0.658  4.787  16.117 1.000 12.347 0 65  TRP AAA CE2 1 ? 
ATOM   547  C CE3 . TRP A 1 67  ? -0.364  5.762  18.312 1.000 14.367 0 65  TRP AAA CE3 1 ? 
ATOM   548  C CZ2 . TRP A 1 67  ? 0.398   3.897  16.317 1.000 13.607 0 65  TRP AAA CZ2 1 ? 
ATOM   549  C CZ3 . TRP A 1 67  ? 0.655   4.863  18.516 1.000 13.448 0 65  TRP AAA CZ3 1 ? 
ATOM   550  C CH2 . TRP A 1 67  ? 1.021   3.956  17.530 1.000 13.203 0 65  TRP AAA CH2 1 ? 
ATOM   551  N N   . PHE A 1 68  ? -4.662  8.079  19.928 1.000 13.842 0 66  PHE AAA N   1 ? 
ATOM   552  C CA  . PHE A 1 68  ? -5.239  9.015  20.897 1.000 14.543 0 66  PHE AAA CA  1 ? 
ATOM   553  C C   . PHE A 1 68  ? -4.411  8.979  22.171 1.000 15.275 0 66  PHE AAA C   1 ? 
ATOM   554  O O   . PHE A 1 68  ? -3.668  8.043  22.406 1.000 14.932 0 66  PHE AAA O   1 ? 
ATOM   555  C CB  . PHE A 1 68  ? -6.721  8.724  21.182 1.000 16.971 0 66  PHE AAA CB  1 ? 
ATOM   556  C CG  . PHE A 1 68  ? -6.990  7.356  21.724 1.000 20.703 0 66  PHE AAA CG  1 ? 
ATOM   557  C CD1 . PHE A 1 68  ? -7.135  7.156  23.083 1.000 25.590 0 66  PHE AAA CD1 1 ? 
ATOM   558  C CD2 . PHE A 1 68  ? -7.105  6.289  20.849 1.000 24.417 0 66  PHE AAA CD2 1 ? 
ATOM   559  C CE1 . PHE A 1 68  ? -7.474  5.897  23.566 1.000 31.409 0 66  PHE AAA CE1 1 ? 
ATOM   560  C CE2 . PHE A 1 68  ? -7.418  5.022  21.329 1.000 27.175 0 66  PHE AAA CE2 1 ? 
ATOM   561  C CZ  . PHE A 1 68  ? -7.581  4.833  22.686 1.000 28.467 0 66  PHE AAA CZ  1 ? 
ATOM   562  N N   . GLY A 1 69  ? -4.465  10.088 22.877 1.000 15.043 0 67  GLY AAA N   1 ? 
ATOM   563  C CA  . GLY A 1 69  ? -3.709  10.207 24.121 1.000 14.568 0 67  GLY AAA CA  1 ? 
ATOM   564  C C   . GLY A 1 69  ? -3.782  11.613 24.663 1.000 14.266 0 67  GLY AAA C   1 ? 
ATOM   565  O O   . GLY A 1 69  ? -4.843  12.262 24.574 1.000 14.937 0 67  GLY AAA O   1 ? 
ATOM   566  N N   . LYS A 1 70  ? -2.670  12.017 25.287 1.000 13.862 0 68  LYS AAA N   1 ? 
ATOM   567  C CA  . LYS A 1 70  ? -2.632  13.292 26.073 1.000 15.651 0 68  LYS AAA CA  1 ? 
ATOM   568  C C   . LYS A 1 70  ? -1.294  13.940 25.758 1.000 13.287 0 68  LYS AAA C   1 ? 
ATOM   569  O O   . LYS A 1 70  ? -0.273  13.260 25.620 1.000 14.787 0 68  LYS AAA O   1 ? 
ATOM   570  C CB  . LYS A 1 70  ? -2.782  13.004 27.571 1.000 18.349 0 68  LYS AAA CB  1 ? 
ATOM   571  C CG  . LYS A 1 70  ? -4.019  12.208 27.969 1.000 20.085 0 68  LYS AAA CG  1 ? 
ATOM   572  C CD  . LYS A 1 70  ? -4.165  11.968 29.475 1.000 25.839 0 68  LYS AAA CD  1 ? 
ATOM   573  C CE  . LYS A 1 70  ? -5.541  11.421 29.783 1.000 30.222 0 68  LYS AAA CE  1 ? 
ATOM   574  N NZ  . LYS A 1 70  ? -5.701  11.163 31.225 1.000 33.677 0 68  LYS AAA NZ  1 ? 
ATOM   575  N N   . CYS A 1 71  ? -1.295  15.260 25.781 1.000 14.222 0 69  CYS AAA N   1 ? 
ATOM   576  C CA  . CYS A 1 71  ? -0.043  16.028 25.872 1.000 14.171 0 69  CYS AAA CA  1 ? 
ATOM   577  C C   . CYS A 1 71  ? -0.141  16.938 27.095 1.000 15.552 0 69  CYS AAA C   1 ? 
ATOM   578  O O   . CYS A 1 71  ? -1.275  17.317 27.481 1.000 15.837 0 69  CYS AAA O   1 ? 
ATOM   579  C CB  . CYS A 1 71  ? 0.261   16.758 24.566 1.000 14.729 0 69  CYS AAA CB  1 ? 
ATOM   580  S SG  . CYS A 1 71  ? -0.851  18.107 24.129 1.000 16.388 0 69  CYS AAA SG  1 ? 
ATOM   581  N N   . TRP A 1 72  ? 1.011   17.378 27.569 1.000 15.704 0 70  TRP AAA N   1 ? 
ATOM   582  C CA  . TRP A 1 72  ? 1.088   18.330 28.704 1.000 18.457 0 70  TRP AAA CA  1 ? 
ATOM   583  C C   . TRP A 1 72  ? 2.004   19.469 28.283 1.000 17.334 0 70  TRP AAA C   1 ? 
ATOM   584  O O   . TRP A 1 72  ? 2.995   19.246 27.542 1.000 19.519 0 70  TRP AAA O   1 ? 
ATOM   585  C CB  . TRP A 1 72  ? 1.617   17.667 29.967 1.000 17.518 0 70  TRP AAA CB  1 ? 
ATOM   586  C CG  . TRP A 1 72  ? 0.733   16.600 30.517 1.000 20.494 0 70  TRP AAA CG  1 ? 
ATOM   587  C CD1 . TRP A 1 72  ? -0.274  16.773 31.417 1.000 21.264 0 70  TRP AAA CD1 1 ? 
ATOM   588  C CD2 . TRP A 1 72  ? 0.717   15.208 30.158 1.000 19.131 0 70  TRP AAA CD2 1 ? 
ATOM   589  N NE1 . TRP A 1 72  ? -0.880  15.573 31.689 1.000 20.828 0 70  TRP AAA NE1 1 ? 
ATOM   590  C CE2 . TRP A 1 72  ? -0.303  14.596 30.930 1.000 18.800 0 70  TRP AAA CE2 1 ? 
ATOM   591  C CE3 . TRP A 1 72  ? 1.502   14.398 29.332 1.000 20.455 0 70  TRP AAA CE3 1 ? 
ATOM   592  C CZ2 . TRP A 1 72  ? -0.582  13.231 30.845 1.000 21.339 0 70  TRP AAA CZ2 1 ? 
ATOM   593  C CZ3 . TRP A 1 72  ? 1.225   13.056 29.265 1.000 21.173 0 70  TRP AAA CZ3 1 ? 
ATOM   594  C CH2 . TRP A 1 72  ? 0.195   12.477 30.010 1.000 22.948 0 70  TRP AAA CH2 1 ? 
ATOM   595  N N   . TYR A 1 73  ? 1.659   20.664 28.704 1.000 15.242 0 71  TYR AAA N   1 ? 
ATOM   596  C CA  . TYR A 1 73  ? 2.463   21.881 28.445 1.000 13.993 0 71  TYR AAA CA  1 ? 
ATOM   597  C C   . TYR A 1 73  ? 2.654   22.627 29.767 1.000 15.406 0 71  TYR AAA C   1 ? 
ATOM   598  O O   . TYR A 1 73  ? 1.658   22.879 30.444 1.000 14.992 0 71  TYR AAA O   1 ? 
ATOM   599  C CB  . TYR A 1 73  ? 1.808   22.766 27.395 1.000 14.724 0 71  TYR AAA CB  1 ? 
ATOM   600  C CG  . TYR A 1 73  ? 2.703   23.894 26.964 1.000 15.468 0 71  TYR AAA CG  1 ? 
ATOM   601  C CD1 . TYR A 1 73  ? 3.714   23.672 26.047 1.000 16.021 0 71  TYR AAA CD1 1 ? 
ATOM   602  C CD2 . TYR A 1 73  ? 2.614   25.130 27.563 1.000 16.226 0 71  TYR AAA CD2 1 ? 
ATOM   603  C CE1 . TYR A 1 73  ? 4.606   24.670 25.734 1.000 17.953 0 71  TYR AAA CE1 1 ? 
ATOM   604  C CE2 . TYR A 1 73  ? 3.551   26.116 27.312 1.000 16.129 0 71  TYR AAA CE2 1 ? 
ATOM   605  C CZ  . TYR A 1 73  ? 4.534   25.895 26.364 1.000 16.938 0 71  TYR AAA CZ  1 ? 
ATOM   606  O OH  . TYR A 1 73  ? 5.435   26.901 26.042 1.000 17.606 0 71  TYR AAA OH  1 ? 
ATOM   607  N N   . ILE A 1 74  ? 3.880   23.024 30.070 1.000 14.312 0 72  ILE AAA N   1 ? 
ATOM   608  C CA  . ILE A 1 74  ? 4.193   23.753 31.336 1.000 15.794 0 72  ILE AAA CA  1 ? 
ATOM   609  C C   . ILE A 1 74  ? 4.336   25.222 30.978 1.000 14.146 0 72  ILE AAA C   1 ? 
ATOM   610  O O   . ILE A 1 74  ? 5.168   25.545 30.086 1.000 16.102 0 72  ILE AAA O   1 ? 
ATOM   611  C CB  . ILE A 1 74  ? 5.431   23.189 32.048 1.000 19.658 0 72  ILE AAA CB  1 ? 
ATOM   612  C CG1 . ILE A 1 74  ? 5.236   21.699 32.361 1.000 26.260 0 72  ILE AAA CG1 1 ? 
ATOM   613  C CG2 . ILE A 1 74  ? 5.686   23.999 33.325 1.000 21.262 0 72  ILE AAA CG2 1 ? 
ATOM   614  C CD1 . ILE A 1 74  ? 6.481   20.979 32.778 1.000 29.721 0 72  ILE AAA CD1 1 ? 
ATOM   615  N N   . HIS A 1 75  ? 3.583   26.092 31.658 1.000 13.212 0 73  HIS AAA N   1 ? 
ATOM   616  C CA  . HIS A 1 75  ? 3.741   27.547 31.490 1.000 13.223 0 73  HIS AAA CA  1 ? 
ATOM   617  C C   . HIS A 1 75  ? 3.765   28.187 32.895 1.000 14.052 0 73  HIS AAA C   1 ? 
ATOM   618  O O   . HIS A 1 75  ? 2.781   28.014 33.622 1.000 13.982 0 73  HIS AAA O   1 ? 
ATOM   619  C CB  . HIS A 1 75  ? 2.615   28.125 30.646 1.000 13.990 0 73  HIS AAA CB  1 ? 
ATOM   620  C CG  . HIS A 1 75  ? 2.867   29.534 30.258 1.000 16.584 0 73  HIS AAA CG  1 ? 
ATOM   621  N ND1 . HIS A 1 75  ? 2.119   30.587 30.760 1.000 20.877 0 73  HIS AAA ND1 1 ? 
ATOM   622  C CD2 . HIS A 1 75  ? 3.801   30.063 29.445 1.000 17.567 0 73  HIS AAA CD2 1 ? 
ATOM   623  C CE1 . HIS A 1 75  ? 2.580   31.710 30.227 1.000 19.943 0 73  HIS AAA CE1 1 ? 
ATOM   624  N NE2 . HIS A 1 75  ? 3.570   31.417 29.423 1.000 23.010 0 73  HIS AAA NE2 1 ? 
ATOM   625  N N   . ASP A 1 76  ? 4.802   28.954 33.190 1.000 14.265 0 74  ASP AAA N   1 ? 
ATOM   626  C CA  . ASP A 1 76  ? 4.925   29.601 34.527 1.000 13.686 0 74  ASP AAA CA  1 ? 
ATOM   627  C C   . ASP A 1 76  ? 4.761   28.525 35.605 1.000 14.003 0 74  ASP AAA C   1 ? 
ATOM   628  O O   . ASP A 1 76  ? 4.093   28.783 36.641 1.000 13.088 0 74  ASP AAA O   1 ? 
ATOM   629  C CB  . ASP A 1 76  ? 3.968   30.786 34.624 1.000 14.082 0 74  ASP AAA CB  1 ? 
ATOM   630  C CG  . ASP A 1 76  ? 4.176   31.925 33.626 1.000 16.374 0 74  ASP AAA CG  1 ? 
ATOM   631  O OD1 . ASP A 1 76  ? 5.264   31.973 33.017 1.000 17.982 0 74  ASP AAA OD1 1 ? 
ATOM   632  O OD2 . ASP A 1 76  ? 3.266   32.770 33.480 1.000 17.515 0 74  ASP AAA OD2 1 ? 
ATOM   633  N N   . LEU A 1 77  ? 5.367   27.342 35.418 1.000 14.515 0 75  LEU AAA N   1 ? 
ATOM   634  C CA  . LEU A 1 77  ? 5.394   26.177 36.314 1.000 14.146 0 75  LEU AAA CA  1 ? 
ATOM   635  C C   . LEU A 1 77  ? 4.037   25.450 36.468 1.000 14.929 0 75  LEU AAA C   1 ? 
ATOM   636  O O   . LEU A 1 77  ? 4.066   24.380 37.136 1.000 19.084 0 75  LEU AAA O   1 ? 
ATOM   637  C CB  . LEU A 1 77  ? 5.955   26.598 37.682 1.000 15.636 0 75  LEU AAA CB  1 ? 
ATOM   638  C CG  . LEU A 1 77  ? 7.443   26.919 37.694 1.000 15.245 0 75  LEU AAA CG  1 ? 
ATOM   639  C CD1 . LEU A 1 77  ? 7.825   27.348 39.095 1.000 15.540 0 75  LEU AAA CD1 1 ? 
ATOM   640  C CD2 . LEU A 1 77  ? 8.323   25.739 37.274 1.000 18.057 0 75  LEU AAA CD2 1 ? 
ATOM   641  N N   . LEU A 1 78  ? 2.958   25.944 35.890 1.000 13.810 0 76  LEU AAA N   1 ? 
ATOM   642  C CA  . LEU A 1 78  ? 1.658   25.228 35.900 1.000 15.374 0 76  LEU AAA CA  1 ? 
ATOM   643  C C   . LEU A 1 78  ? 1.631   24.254 34.720 1.000 13.907 0 76  LEU AAA C   1 ? 
ATOM   644  O O   . LEU A 1 78  ? 2.012   24.630 33.587 1.000 14.667 0 76  LEU AAA O   1 ? 
ATOM   645  C CB  . LEU A 1 78  ? 0.492   26.198 35.847 1.000 14.911 0 76  LEU AAA CB  1 ? 
ATOM   646  C CG  . LEU A 1 78  ? 0.337   27.042 37.116 1.000 15.384 0 76  LEU AAA CG  1 ? 
ATOM   647  C CD1 . LEU A 1 78  ? -0.727  28.097 36.916 1.000 15.696 0 76  LEU AAA CD1 1 ? 
ATOM   648  C CD2 . LEU A 1 78  ? 0.062   26.174 38.332 1.000 15.580 0 76  LEU AAA CD2 1 ? 
ATOM   649  N N   . LYS A 1 79  ? 1.110   23.063 34.986 1.000 15.961 0 77  LYS AAA N   1 ? 
ATOM   650  C CA  . LYS A 1 79  ? 1.030   22.000 33.938 1.000 17.577 0 77  LYS AAA CA  1 ? 
ATOM   651  C C   . LYS A 1 79  ? -0.376  21.944 33.354 1.000 18.804 0 77  LYS AAA C   1 ? 
ATOM   652  O O   . LYS A 1 79  ? -1.376  21.819 34.110 1.000 19.820 0 77  LYS AAA O   1 ? 
ATOM   653  C CB  . LYS A 1 79  ? 1.473   20.669 34.549 1.000 19.169 0 77  LYS AAA CB  1 ? 
ATOM   654  C CG  . LYS A 1 79  ? 1.515   19.515 33.547 1.000 22.043 0 77  LYS AAA CG  1 ? 
ATOM   655  C CD  . LYS A 1 79  ? 2.338   18.318 34.054 1.000 26.225 0 77  LYS AAA CD  1 ? 
ATOM   656  C CE  . LYS A 1 79  ? 1.806   17.750 35.342 1.000 34.513 0 77  LYS AAA CE  1 ? 
ATOM   657  N N   . TYR A 1 80  ? -0.496  22.074 32.038 1.000 15.489 0 78  TYR AAA N   1 ? 
ATOM   658  C CA  . TYR A 1 80  ? -1.774  22.057 31.306 1.000 16.854 0 78  TYR AAA CA  1 ? 
ATOM   659  C C   . TYR A 1 80  ? -1.866  20.755 30.516 1.000 16.922 0 78  TYR AAA C   1 ? 
ATOM   660  O O   . TYR A 1 80  ? -0.903  20.379 29.819 1.000 19.198 0 78  TYR AAA O   1 ? 
ATOM   661  C CB  . TYR A 1 80  ? -1.879  23.268 30.373 1.000 16.046 0 78  TYR AAA CB  1 ? 
ATOM   662  C CG  . TYR A 1 80  ? -1.871  24.591 31.088 1.000 15.744 0 78  TYR AAA CG  1 ? 
ATOM   663  C CD1 . TYR A 1 80  ? -3.043  25.282 31.267 1.000 16.170 0 78  TYR AAA CD1 1 ? 
ATOM   664  C CD2 . TYR A 1 80  ? -0.696  25.154 31.554 1.000 16.111 0 78  TYR AAA CD2 1 ? 
ATOM   665  C CE1 . TYR A 1 80  ? -3.080  26.487 31.954 1.000 17.689 0 78  TYR AAA CE1 1 ? 
ATOM   666  C CE2 . TYR A 1 80  ? -0.718  26.361 32.239 1.000 16.338 0 78  TYR AAA CE2 1 ? 
ATOM   667  C CZ  . TYR A 1 80  ? -1.898  27.047 32.411 1.000 17.778 0 78  TYR AAA CZ  1 ? 
ATOM   668  O OH  . TYR A 1 80  ? -1.976  28.270 33.050 1.000 18.271 0 78  TYR AAA OH  1 ? 
ATOM   669  N N   . GLU A 1 81  ? -2.997  20.080 30.594 1.000 16.888 0 79  GLU AAA N   1 ? 
ATOM   670  C CA  . GLU A 1 81  ? -3.187  18.813 29.829 1.000 16.680 0 79  GLU AAA CA  1 ? 
ATOM   671  C C   . GLU A 1 81  ? -4.215  19.035 28.720 1.000 15.520 0 79  GLU AAA C   1 ? 
ATOM   672  O O   . GLU A 1 81  ? -5.219  19.747 28.900 1.000 17.669 0 79  GLU AAA O   1 ? 
ATOM   673  C CB  . GLU A 1 81  ? -3.640  17.676 30.740 1.000 17.688 0 79  GLU AAA CB  1 ? 
ATOM   674  C CG  . GLU A 1 81  ? -3.837  16.313 30.068 1.000 18.916 0 79  GLU AAA CG  1 ? 
ATOM   675  C CD  . GLU A 1 81  ? -5.096  16.085 29.242 1.000 23.311 0 79  GLU AAA CD  1 ? 
ATOM   676  O OE1 . GLU A 1 81  ? -6.103  16.790 29.447 1.000 22.636 0 79  GLU AAA OE1 1 ? 
ATOM   677  O OE2 . GLU A 1 81  ? -5.031  15.192 28.338 1.000 24.151 0 79  GLU AAA OE2 1 ? 
ATOM   678  N N   . PHE A 1 82  ? -3.977  18.460 27.523 1.000 14.857 0 80  PHE AAA N   1 ? 
ATOM   679  C CA  . PHE A 1 82  ? -4.891  18.482 26.371 1.000 14.877 0 80  PHE AAA CA  1 ? 
ATOM   680  C C   . PHE A 1 82  ? -4.924  17.064 25.744 1.000 14.234 0 80  PHE AAA C   1 ? 
ATOM   681  O O   . PHE A 1 82  ? -3.923  16.432 25.480 1.000 15.600 0 80  PHE AAA O   1 ? 
ATOM   682  C CB  . PHE A 1 82  ? -4.511  19.508 25.311 1.000 14.980 0 80  PHE AAA CB  1 ? 
ATOM   683  C CG  . PHE A 1 82  ? -4.180  20.876 25.861 1.000 16.134 0 80  PHE AAA CG  1 ? 
ATOM   684  C CD1 . PHE A 1 82  ? -5.176  21.803 26.132 1.000 18.785 0 80  PHE AAA CD1 1 ? 
ATOM   685  C CD2 . PHE A 1 82  ? -2.863  21.193 26.164 1.000 16.952 0 80  PHE AAA CD2 1 ? 
ATOM   686  C CE1 . PHE A 1 82  ? -4.847  23.037 26.693 1.000 19.258 0 80  PHE AAA CE1 1 ? 
ATOM   687  C CE2 . PHE A 1 82  ? -2.544  22.434 26.700 1.000 16.386 0 80  PHE AAA CE2 1 ? 
ATOM   688  C CZ  . PHE A 1 82  ? -3.542  23.329 27.005 1.000 17.332 0 80  PHE AAA CZ  1 ? 
ATOM   689  N N   . ASP A 1 83  ? -6.160  16.575 25.564 1.000 15.789 0 81  ASP AAA N   1 ? 
ATOM   690  C CA  . ASP A 1 83  ? -6.402  15.309 24.850 1.000 16.783 0 81  ASP AAA CA  1 ? 
ATOM   691  C C   . ASP A 1 83  ? -6.060  15.538 23.375 1.000 14.739 0 81  ASP AAA C   1 ? 
ATOM   692  O O   . ASP A 1 83  ? -6.397  16.588 22.806 1.000 16.985 0 81  ASP AAA O   1 ? 
ATOM   693  C CB  . ASP A 1 83  ? -7.870  14.896 25.010 1.000 17.810 0 81  ASP AAA CB  1 ? 
ATOM   694  C CG  . ASP A 1 83  ? -8.198  14.415 26.421 1.000 21.107 0 81  ASP AAA CG  1 ? 
ATOM   695  O OD1 . ASP A 1 83  ? -7.319  14.319 27.243 1.000 22.643 0 81  ASP AAA OD1 1 ? 
ATOM   696  O OD2 . ASP A 1 83  ? -9.347  13.977 26.619 1.000 29.181 0 81  ASP AAA OD2 1 ? 
ATOM   697  N N   . ILE A 1 84  ? -5.440  14.559 22.734 1.000 13.158 0 82  ILE AAA N   1 ? 
ATOM   698  C CA  . ILE A 1 84  ? -5.088  14.624 21.290 1.000 13.890 0 82  ILE AAA CA  1 ? 
ATOM   699  C C   . ILE A 1 84  ? -5.581  13.337 20.598 1.000 13.720 0 82  ILE AAA C   1 ? 
ATOM   700  O O   . ILE A 1 84  ? -5.701  12.290 21.247 1.000 14.572 0 82  ILE AAA O   1 ? 
ATOM   701  C CB  . ILE A 1 84  ? -3.544  14.779 21.162 1.000 15.079 0 82  ILE AAA CB  1 ? 
ATOM   702  C CG1 . ILE A 1 84  ? -2.704  13.657 21.776 1.000 15.527 0 82  ILE AAA CG1 1 ? 
ATOM   703  C CG2 . ILE A 1 84  ? -3.101  16.156 21.682 1.000 16.540 0 82  ILE AAA CG2 1 ? 
ATOM   704  C CD1 . ILE A 1 84  ? -1.205  13.817 21.494 1.000 17.082 0 82  ILE AAA CD1 1 ? 
ATOM   705  N N   . GLU A 1 85  ? -5.751  13.405 19.286 1.000 13.787 0 83  GLU AAA N   1 ? 
ATOM   706  C CA  . GLU A 1 85  ? -6.194  12.219 18.499 1.000 14.223 0 83  GLU AAA CA  1 ? 
ATOM   707  C C   . GLU A 1 85  ? -5.857  12.469 17.036 1.000 15.788 0 83  GLU AAA C   1 ? 
ATOM   708  O O   . GLU A 1 85  ? -5.700  13.620 16.600 1.000 14.188 0 83  GLU AAA O   1 ? 
ATOM   709  C CB  . GLU A 1 85  ? -7.687  11.921 18.681 1.000 16.801 0 83  GLU AAA CB  1 ? 
ATOM   710  C CG  . GLU A 1 85  ? -8.578  13.052 18.237 1.000 19.210 0 83  GLU AAA CG  1 ? 
ATOM   711  C CD  . GLU A 1 85  ? -10.055 12.840 18.574 1.000 22.375 0 83  GLU AAA CD  1 ? 
ATOM   712  O OE1 . GLU A 1 85  ? -10.348 12.439 19.677 1.000 25.724 0 83  GLU AAA OE1 1 ? 
ATOM   713  O OE2 . GLU A 1 85  ? -10.871 13.107 17.713 1.000 31.373 0 83  GLU AAA OE2 1 ? 
ATOM   714  N N   . PHE A 1 86  ? -5.666  11.367 16.299 1.000 12.639 0 84  PHE AAA N   1 ? 
ATOM   715  C CA  . PHE A 1 86  ? -5.493  11.435 14.829 1.000 13.570 0 84  PHE AAA CA  1 ? 
ATOM   716  C C   . PHE A 1 86  ? -5.794  10.074 14.215 1.000 15.394 0 84  PHE AAA C   1 ? 
ATOM   717  O O   . PHE A 1 86  ? -5.587  9.038  14.833 1.000 15.404 0 84  PHE AAA O   1 ? 
ATOM   718  C CB  . PHE A 1 86  ? -4.143  12.019 14.410 1.000 13.737 0 84  PHE AAA CB  1 ? 
ATOM   719  C CG  . PHE A 1 86  ? -2.922  11.379 15.000 1.000 12.699 0 84  PHE AAA CG  1 ? 
ATOM   720  C CD1 . PHE A 1 86  ? -2.300  10.290 14.381 1.000 13.830 0 84  PHE AAA CD1 1 ? 
ATOM   721  C CD2 . PHE A 1 86  ? -2.410  11.793 16.228 1.000 14.004 0 84  PHE AAA CD2 1 ? 
ATOM   722  C CE1 . PHE A 1 86  ? -1.183  9.697  14.935 1.000 13.388 0 84  PHE AAA CE1 1 ? 
ATOM   723  C CE2 . PHE A 1 86  ? -1.306  11.197 16.775 1.000 13.183 0 84  PHE AAA CE2 1 ? 
ATOM   724  C CZ  . PHE A 1 86  ? -0.666  10.172 16.127 1.000 12.984 0 84  PHE AAA CZ  1 ? 
ATOM   725  N N   . ASP A 1 87  ? -6.188  10.139 12.962 1.000 15.709 0 85  ASP AAA N   1 ? 
ATOM   726  C CA  . ASP A 1 87  ? -6.347  8.950  12.078 1.000 17.345 0 85  ASP AAA CA  1 ? 
ATOM   727  C C   . ASP A 1 87  ? -5.105  8.888  11.207 1.000 16.343 0 85  ASP AAA C   1 ? 
ATOM   728  O O   . ASP A 1 87  ? -4.438  9.909  10.874 1.000 17.024 0 85  ASP AAA O   1 ? 
ATOM   729  C CB  . ASP A 1 87  ? -7.696  8.983  11.337 1.000 20.339 0 85  ASP AAA CB  1 ? 
ATOM   730  C CG  . ASP A 1 87  ? -8.847  9.300  12.296 1.000 27.267 0 85  ASP AAA CG  1 ? 
ATOM   731  O OD2 . ASP A 1 87  ? -10.007 8.898  12.048 1.000 43.278 0 85  ASP AAA OD2 1 ? 
ATOM   732  N N   . ILE A 1 88  ? -4.705  7.664  10.856 1.000 14.260 0 86  ILE AAA N   1 ? 
ATOM   733  C CA  . ILE A 1 88  ? -3.614  7.441  9.877  1.000 14.235 0 86  ILE AAA CA  1 ? 
ATOM   734  C C   . ILE A 1 88  ? -4.198  7.506  8.459  1.000 16.015 0 86  ILE AAA C   1 ? 
ATOM   735  O O   . ILE A 1 88  ? -4.989  6.650  8.128  1.000 16.447 0 86  ILE AAA O   1 ? 
ATOM   736  C CB  . ILE A 1 88  ? -2.873  6.101  10.103 1.000 13.691 0 86  ILE AAA CB  1 ? 
ATOM   737  C CG1 . ILE A 1 88  ? -2.305  6.001  11.533 1.000 13.781 0 86  ILE AAA CG1 1 ? 
ATOM   738  C CG2 . ILE A 1 88  ? -1.811  5.861  9.072  1.000 14.809 0 86  ILE AAA CG2 1 ? 
ATOM   739  C CD1 . ILE A 1 88  ? -1.255  7.053  11.885 1.000 13.591 0 86  ILE AAA CD1 1 ? 
ATOM   740  N N   . PRO A 1 89  ? -3.733  8.420  7.584  1.000 16.083 0 87  PRO AAA N   1 ? 
ATOM   741  C CA  . PRO A 1 89  ? -4.145  8.442  6.183  1.000 16.618 0 87  PRO AAA CA  1 ? 
ATOM   742  C C   . PRO A 1 89  ? -3.807  7.113  5.479  1.000 16.833 0 87  PRO AAA C   1 ? 
ATOM   743  O O   . PRO A 1 89  ? -2.784  6.491  5.724  1.000 16.670 0 87  PRO AAA O   1 ? 
ATOM   744  C CB  . PRO A 1 89  ? -3.300  9.575  5.606  1.000 17.823 0 87  PRO AAA CB  1 ? 
ATOM   745  C CG  . PRO A 1 89  ? -2.877  10.393 6.742  1.000 19.763 0 87  PRO AAA CG  1 ? 
ATOM   746  C CD  . PRO A 1 89  ? -2.703  9.434  7.896  1.000 17.287 0 87  PRO AAA CD  1 ? 
ATOM   747  N N   . ILE A 1 90  ? -4.609  6.751  4.485  1.000 17.898 0 88  ILE AAA N   1 ? 
ATOM   748  C CA  . ILE A 1 90  ? -4.331  5.537  3.682  1.000 19.272 0 88  ILE AAA CA  1 ? 
ATOM   749  C C   . ILE A 1 90  ? -2.969  5.640  3.007  1.000 15.893 0 88  ILE AAA C   1 ? 
ATOM   750  O O   . ILE A 1 90  ? -2.296  4.604  2.874  1.000 17.578 0 88  ILE AAA O   1 ? 
ATOM   751  C CB  . ILE A 1 90  ? -5.473  5.352  2.671  1.000 21.950 0 88  ILE AAA CB  1 ? 
ATOM   752  C CG1 . ILE A 1 90  ? -6.832  5.222  3.365  1.000 24.307 0 88  ILE AAA CG1 1 ? 
ATOM   753  C CG2 . ILE A 1 90  ? -5.156  4.185  1.757  1.000 22.677 0 88  ILE AAA CG2 1 ? 
ATOM   754  C CD1 . ILE A 1 90  ? -6.888  4.166  4.435  1.000 25.987 0 88  ILE AAA CD1 1 ? 
ATOM   755  N N   . THR A 1 91  ? -2.504  6.866  2.628  1.000 16.578 0 89  THR AAA N   1 ? 
ATOM   756  C CA  . THR A 1 91  ? -1.248  7.082  1.907  1.000 18.199 0 89  THR AAA CA  1 ? 
ATOM   757  C C   . THR A 1 91  ? -0.112  7.459  2.872  1.000 15.342 0 89  THR AAA C   1 ? 
ATOM   758  O O   . THR A 1 91  ? 0.960   7.816  2.417  1.000 16.403 0 89  THR AAA O   1 ? 
ATOM   759  C CB  . THR A 1 91  ? -1.405  8.173  0.850  1.000 21.072 0 89  THR AAA CB  1 ? 
ATOM   760  O OG1 . THR A 1 91  ? -1.995  9.266  1.542  1.000 22.573 0 89  THR AAA OG1 1 ? 
ATOM   761  C CG2 . THR A 1 91  ? -2.279  7.699  -0.300 1.000 22.827 0 89  THR AAA CG2 1 ? 
ATOM   762  N N   . TYR A 1 92  ? -0.326  7.260  4.188  1.000 14.355 0 90  TYR AAA N   1 ? 
ATOM   763  C CA  . TYR A 1 92  ? 0.801   7.270  5.128  1.000 14.246 0 90  TYR AAA CA  1 ? 
ATOM   764  C C   . TYR A 1 92  ? 1.814   6.207  4.714  1.000 14.328 0 90  TYR AAA C   1 ? 
ATOM   765  O O   . TYR A 1 92  ? 1.355   5.136  4.289  1.000 17.484 0 90  TYR AAA O   1 ? 
ATOM   766  C CB  . TYR A 1 92  ? 0.248   7.001  6.518  1.000 13.257 0 90  TYR AAA CB  1 ? 
ATOM   767  C CG  . TYR A 1 92  ? 1.230   7.159  7.658  1.000 13.054 0 90  TYR AAA CG  1 ? 
ATOM   768  C CD1 . TYR A 1 92  ? 1.565   8.415  8.117  1.000 12.652 0 90  TYR AAA CD1 1 ? 
ATOM   769  C CD2 . TYR A 1 92  ? 1.887   6.057  8.217  1.000 12.954 0 90  TYR AAA CD2 1 ? 
ATOM   770  C CE1 . TYR A 1 92  ? 2.448   8.598  9.164  1.000 12.437 0 90  TYR AAA CE1 1 ? 
ATOM   771  C CE2 . TYR A 1 92  ? 2.790   6.234  9.256  1.000 12.365 0 90  TYR AAA CE2 1 ? 
ATOM   772  C CZ  . TYR A 1 92  ? 3.105   7.504  9.702  1.000 13.178 0 90  TYR AAA CZ  1 ? 
ATOM   773  O OH  . TYR A 1 92  ? 4.020   7.682  10.710 1.000 12.246 0 90  TYR AAA OH  1 ? 
ATOM   774  N N   . PRO A 1 93  ? 3.149   6.357  4.888  1.000 15.037 0 91  PRO AAA N   1 ? 
ATOM   775  C CA  . PRO A 1 93  ? 3.776   7.491  5.572  1.000 14.167 0 91  PRO AAA CA  1 ? 
ATOM   776  C C   . PRO A 1 93  ? 4.181   8.658  4.674  1.000 15.867 0 91  PRO AAA C   1 ? 
ATOM   777  O O   . PRO A 1 93  ? 4.927   9.535  5.097  1.000 15.038 0 91  PRO AAA O   1 ? 
ATOM   778  C CB  . PRO A 1 93  ? 5.059   6.871  6.178  1.000 14.853 0 91  PRO AAA CB  1 ? 
ATOM   779  C CG  . PRO A 1 93  ? 5.450   5.856  5.114  1.000 16.850 0 91  PRO AAA CG  1 ? 
ATOM   780  C CD  . PRO A 1 93  ? 4.132   5.255  4.683  1.000 15.722 0 91  PRO AAA CD  1 ? 
ATOM   781  N N   . THR A 1 94  ? 3.836   8.618  3.388  1.000 16.103 0 92  THR AAA N   1 ? 
ATOM   782  C CA  . THR A 1 94  ? 4.224   9.704  2.462  1.000 17.081 0 92  THR AAA CA  1 ? 
ATOM   783  C C   . THR A 1 94  ? 3.390   10.924 2.838  1.000 16.501 0 92  THR AAA C   1 ? 
ATOM   784  O O   . THR A 1 94  ? 3.956   12.078 2.697  1.000 20.914 0 92  THR AAA O   1 ? 
ATOM   785  C CB  . THR A 1 94  ? 4.093   9.187  1.014  1.000 16.992 0 92  THR AAA CB  1 ? 
ATOM   786  O OG1 . THR A 1 94  ? 5.045   8.157  0.836  1.000 20.866 0 92  THR AAA OG1 1 ? 
ATOM   787  C CG2 . THR A 1 94  ? 4.439   10.226 -0.023 1.000 22.633 0 92  THR AAA CG2 1 ? 
ATOM   788  N N   . THR A 1 95  ? 2.147   10.747 3.257  1.000 15.638 0 93  THR AAA N   1 ? 
ATOM   789  C CA  . THR A 1 95  ? 1.253   11.821 3.731  1.000 16.177 0 93  THR AAA CA  1 ? 
ATOM   790  C C   . THR A 1 95  ? 1.408   11.897 5.256  1.000 19.079 0 93  THR AAA C   1 ? 
ATOM   791  O O   . THR A 1 95  ? 1.333   10.808 5.873  1.000 23.939 0 93  THR AAA O   1 ? 
ATOM   792  C CB  . THR A 1 95  ? -0.205  11.518 3.370  1.000 21.030 0 93  THR AAA CB  1 ? 
ATOM   793  O OG1 . THR A 1 95  ? -0.177  11.497 1.924  1.000 25.135 0 93  THR AAA OG1 1 ? 
ATOM   794  C CG2 . THR A 1 95  ? -1.210  12.504 3.905  1.000 25.478 0 93  THR AAA CG2 1 ? 
ATOM   795  N N   . ALA A 1 96  ? 1.453   13.066 5.857  1.000 16.080 0 94  ALA AAA N   1 ? 
ATOM   796  C CA  . ALA A 1 96  ? 1.518   13.191 7.330  1.000 15.863 0 94  ALA AAA CA  1 ? 
ATOM   797  C C   . ALA A 1 96  ? 0.115   13.168 7.931  1.000 16.833 0 94  ALA AAA C   1 ? 
ATOM   798  O O   . ALA A 1 96  ? -0.824  13.776 7.409  1.000 18.378 0 94  ALA AAA O   1 ? 
ATOM   799  C CB  . ALA A 1 96  ? 2.231   14.455 7.684  1.000 17.596 0 94  ALA AAA CB  1 ? 
ATOM   800  N N   . PRO A 1 97  ? -0.079  12.546 9.112  1.000 15.322 0 95  PRO AAA N   1 ? 
ATOM   801  C CA  . PRO A 1 97  ? -1.343  12.602 9.825  1.000 14.826 0 95  PRO AAA CA  1 ? 
ATOM   802  C C   . PRO A 1 97  ? -1.677  14.024 10.310 1.000 14.765 0 95  PRO AAA C   1 ? 
ATOM   803  O O   . PRO A 1 97  ? -0.699  14.798 10.494 1.000 15.275 0 95  PRO AAA O   1 ? 
ATOM   804  C CB  . PRO A 1 97  ? -1.176  11.613 10.999 1.000 15.299 0 95  PRO AAA CB  1 ? 
ATOM   805  C CG  . PRO A 1 97  ? 0.041   10.792 10.627 1.000 15.511 0 95  PRO AAA CG  1 ? 
ATOM   806  C CD  . PRO A 1 97  ? 0.916   11.686 9.787  1.000 15.605 0 95  PRO AAA CD  1 ? 
ATOM   807  N N   . GLU A 1 98  ? -2.965  14.294 10.502 1.000 15.928 0 96  GLU AAA N   1 ? 
ATOM   808  C CA  . GLU A 1 98  ? -3.500  15.599 10.980 1.000 15.967 0 96  GLU AAA CA  1 ? 
ATOM   809  C C   . GLU A 1 98  ? -3.860  15.464 12.464 1.000 14.955 0 96  GLU AAA C   1 ? 
ATOM   810  O O   . GLU A 1 98  ? -4.912  14.972 12.807 1.000 16.766 0 96  GLU AAA O   1 ? 
ATOM   811  C CB  . GLU A 1 98  ? -4.695  16.039 10.140 1.000 19.689 0 96  GLU AAA CB  1 ? 
ATOM   812  C CG  . GLU A 1 98  ? -4.314  16.267 8.690  1.000 22.117 0 96  GLU AAA CG  1 ? 
ATOM   813  C CD  . GLU A 1 98  ? -5.484  16.651 7.789  1.000 28.340 0 96  GLU AAA CD  1 ? 
ATOM   814  O OE1 . GLU A 1 98  ? -6.564  16.154 8.007  1.000 30.493 0 96  GLU AAA OE1 1 ? 
ATOM   815  O OE2 . GLU A 1 98  ? -5.288  17.466 6.864  1.000 42.344 0 96  GLU AAA OE2 1 ? 
ATOM   816  N N   . ILE A 1 99  ? -3.000  15.985 13.335 1.000 15.153 0 97  ILE AAA N   1 ? 
ATOM   817  C CA  . ILE A 1 99  ? -3.214  15.969 14.804 1.000 15.639 0 97  ILE AAA CA  1 ? 
ATOM   818  C C   . ILE A 1 99  ? -4.343  16.930 15.141 1.000 16.536 0 97  ILE AAA C   1 ? 
ATOM   819  O O   . ILE A 1 99  ? -4.328  18.067 14.657 1.000 17.531 0 97  ILE AAA O   1 ? 
ATOM   820  C CB  . ILE A 1 99  ? -1.942  16.325 15.569 1.000 16.941 0 97  ILE AAA CB  1 ? 
ATOM   821  C CG1 . ILE A 1 99  ? -0.874  15.257 15.378 1.000 16.420 0 97  ILE AAA CG1 1 ? 
ATOM   822  C CG2 . ILE A 1 99  ? -2.227  16.490 17.070 1.000 16.459 0 97  ILE AAA CG2 1 ? 
ATOM   823  C CD1 . ILE A 1 99  ? 0.476   15.582 15.958 1.000 16.878 0 97  ILE AAA CD1 1 ? 
ATOM   824  N N   . ALA A 1 100 ? -5.276  16.445 15.923 1.000 15.205 0 98  ALA AAA N   1 ? 
ATOM   825  C CA  . ALA A 1 100 ? -6.377  17.268 16.449 1.000 15.193 0 98  ALA AAA CA  1 ? 
ATOM   826  C C   . ALA A 1 100 ? -6.215  17.353 17.974 1.000 15.893 0 98  ALA AAA C   1 ? 
ATOM   827  O O   . ALA A 1 100 ? -5.871  16.391 18.657 1.000 15.793 0 98  ALA AAA O   1 ? 
ATOM   828  C CB  . ALA A 1 100 ? -7.706  16.676 16.033 1.000 17.607 0 98  ALA AAA CB  1 ? 
ATOM   829  N N   . VAL A 1 101 ? -6.525  18.558 18.448 1.000 15.138 0 99  VAL AAA N   1 ? 
ATOM   830  C CA  . VAL A 1 101 ? -6.658  18.845 19.906 1.000 15.794 0 99  VAL AAA CA  1 ? 
ATOM   831  C C   . VAL A 1 101 ? -8.078  19.327 20.122 1.000 16.858 0 99  VAL AAA C   1 ? 
ATOM   832  O O   . VAL A 1 101 ? -8.344  20.525 20.135 1.000 16.551 0 99  VAL AAA O   1 ? 
ATOM   833  C CB  . VAL A 1 101 ? -5.618  19.894 20.359 1.000 16.073 0 99  VAL AAA CB  1 ? 
ATOM   834  C CG1 . VAL A 1 101 ? -5.641  20.082 21.866 1.000 17.716 0 99  VAL AAA CG1 1 ? 
ATOM   835  C CG2 . VAL A 1 101 ? -4.216  19.529 19.919 1.000 16.487 0 99  VAL AAA CG2 1 ? 
ATOM   836  N N   . PRO A 1 102 ? -9.073  18.415 20.184 1.000 18.686 0 100 PRO AAA N   1 ? 
ATOM   837  C CA  . PRO A 1 102 ? -10.472 18.837 20.107 1.000 19.702 0 100 PRO AAA CA  1 ? 
ATOM   838  C C   . PRO A 1 102 ? -10.953 19.883 21.129 1.000 17.431 0 100 PRO AAA C   1 ? 
ATOM   839  O O   . PRO A 1 102 ? -11.822 20.652 20.739 1.000 19.674 0 100 PRO AAA O   1 ? 
ATOM   840  C CB  . PRO A 1 102 ? -11.233 17.507 20.309 1.000 23.264 0 100 PRO AAA CB  1 ? 
ATOM   841  C CG  . PRO A 1 102 ? -10.264 16.487 19.727 1.000 23.448 0 100 PRO AAA CG  1 ? 
ATOM   842  C CD  . PRO A 1 102 ? -8.904  16.948 20.237 1.000 21.522 0 100 PRO AAA CD  1 ? 
ATOM   843  N N   . GLU A 1 103 ? -10.403 19.893 22.339 1.000 17.173 0 101 GLU AAA N   1 ? 
ATOM   844  C CA  . GLU A 1 103 ? -10.888 20.889 23.326 1.000 18.985 0 101 GLU AAA CA  1 ? 
ATOM   845  C C   . GLU A 1 103 ? -10.458 22.300 22.924 1.000 18.267 0 101 GLU AAA C   1 ? 
ATOM   846  O O   . GLU A 1 103 ? -11.095 23.286 23.400 1.000 19.896 0 101 GLU AAA O   1 ? 
ATOM   847  C CB  . GLU A 1 103 ? -10.434 20.540 24.723 1.000 20.783 0 101 GLU AAA CB  1 ? 
ATOM   848  C CG  . GLU A 1 103 ? -8.986  20.758 25.035 1.000 24.532 0 101 GLU AAA CG  1 ? 
ATOM   849  C CD  . GLU A 1 103 ? -8.548  19.901 26.224 1.000 30.524 0 101 GLU AAA CD  1 ? 
ATOM   850  O OE1 . GLU A 1 103 ? -8.419  18.632 26.070 1.000 28.192 0 101 GLU AAA OE1 1 ? 
ATOM   851  O OE2 . GLU A 1 103 ? -8.464  20.469 27.346 1.000 38.483 0 101 GLU AAA OE2 1 ? 
ATOM   852  N N   . LEU A 1 104 ? -9.482  22.463 22.030 1.000 16.964 0 102 LEU AAA N   1 ? 
ATOM   853  C CA  . LEU A 1 104 ? -9.087  23.825 21.593 1.000 16.548 0 102 LEU AAA CA  1 ? 
ATOM   854  C C   . LEU A 1 104 ? -9.744  24.238 20.280 1.000 15.493 0 102 LEU AAA C   1 ? 
ATOM   855  O O   . LEU A 1 104 ? -9.460  25.299 19.809 1.000 15.908 0 102 LEU AAA O   1 ? 
ATOM   856  C CB  . LEU A 1 104 ? -7.559  23.874 21.475 1.000 16.016 0 102 LEU AAA CB  1 ? 
ATOM   857  C CG  . LEU A 1 104 ? -6.787  23.684 22.773 1.000 17.145 0 102 LEU AAA CG  1 ? 
ATOM   858  C CD1 . LEU A 1 104 ? -5.259  23.834 22.579 1.000 19.026 0 102 LEU AAA CD1 1 ? 
ATOM   859  C CD2 . LEU A 1 104 ? -7.284  24.636 23.855 1.000 18.409 0 102 LEU AAA CD2 1 ? 
ATOM   860  N N   . ASP A 1 105 ? -10.644 23.426 19.726 1.000 16.124 0 103 ASP AAA N   1 ? 
ATOM   861  C CA  . ASP A 1 105 ? -11.365 23.744 18.473 1.000 15.385 0 103 ASP AAA CA  1 ? 
ATOM   862  C C   . ASP A 1 105 ? -12.008 25.145 18.601 1.000 16.610 0 103 ASP AAA C   1 ? 
ATOM   863  O O   . ASP A 1 105 ? -12.624 25.393 19.658 1.000 19.153 0 103 ASP AAA O   1 ? 
ATOM   864  C CB  . ASP A 1 105 ? -12.421 22.657 18.248 1.000 16.352 0 103 ASP AAA CB  1 ? 
ATOM   865  C CG  . ASP A 1 105 ? -13.203 22.746 16.951 1.000 17.637 0 103 ASP AAA CG  1 ? 
ATOM   866  O OD1 . ASP A 1 105 ? -12.781 23.431 16.015 1.000 20.126 0 103 ASP AAA OD1 1 ? 
ATOM   867  O OD2 . ASP A 1 105 ? -14.344 22.164 16.920 1.000 20.951 0 103 ASP AAA OD2 1 ? 
ATOM   868  N N   . GLY A 1 106 ? -11.698 25.972 17.624 1.000 22.455 0 104 GLY AAA N   1 ? 
ATOM   869  C CA  . GLY A 1 106 ? -12.120 27.393 17.542 1.000 24.211 0 104 GLY AAA CA  1 ? 
ATOM   870  C C   . GLY A 1 106 ? -11.493 28.289 18.608 1.000 27.310 0 104 GLY AAA C   1 ? 
ATOM   871  O O   . GLY A 1 106 ? -12.023 29.414 18.886 1.000 28.293 0 104 GLY AAA O   1 ? 
ATOM   872  N N   . LYS A 1 107 ? -10.411 27.877 19.251 1.000 22.334 0 105 LYS AAA N   1 ? 
ATOM   873  C CA  . LYS A 1 107 ? -9.796  28.722 20.315 1.000 21.484 0 105 LYS AAA CA  1 ? 
ATOM   874  C C   . LYS A 1 107 ? -8.482  29.316 19.795 1.000 23.758 0 105 LYS AAA C   1 ? 
ATOM   875  O O   . LYS A 1 107 ? -8.130  30.378 20.258 1.000 25.561 0 105 LYS AAA O   1 ? 
ATOM   876  C CB  . LYS A 1 107 ? -9.617  27.944 21.611 1.000 23.007 0 105 LYS AAA CB  1 ? 
ATOM   877  C CG  . LYS A 1 107 ? -10.915 27.595 22.345 1.000 21.614 0 105 LYS AAA CG  1 ? 
ATOM   878  C CD  . LYS A 1 107 ? -10.770 27.047 23.726 1.000 24.811 0 105 LYS AAA CD  1 ? 
ATOM   879  C CE  . LYS A 1 107 ? -12.107 26.554 24.278 1.000 26.767 0 105 LYS AAA CE  1 ? 
ATOM   880  N NZ  . LYS A 1 107 ? -11.917 25.550 25.340 1.000 30.329 0 105 LYS AAA NZ  1 ? 
ATOM   881  N N   . SER A 1 108 ? -7.826  28.699 18.812 1.000 23.247 0 106 SER AAA N   1 ? 
ATOM   882  C CA  . SER A 1 108 ? -6.573  29.216 18.169 1.000 22.875 0 106 SER AAA CA  1 ? 
ATOM   883  C C   . SER A 1 108 ? -6.842  29.554 16.708 1.000 21.698 0 106 SER AAA C   1 ? 
ATOM   884  O O   . SER A 1 108 ? -7.487  28.762 16.096 1.000 24.192 0 106 SER AAA O   1 ? 
ATOM   885  C CB  . SER A 1 108 ? -5.449  28.193 18.264 1.000 23.700 0 106 SER AAA CB  1 ? 
ATOM   886  O OG  . SER A 1 108 ? -4.366  28.538 17.397 1.000 26.240 0 106 SER AAA OG  1 ? 
ATOM   887  N N   . ALA A 1 109 ? -6.309  30.635 16.111 1.000 24.155 0 107 ALA AAA N   1 ? 
ATOM   888  C CA  . ALA A 1 109 ? -6.406  30.907 14.654 1.000 24.738 0 107 ALA AAA CA  1 ? 
ATOM   889  C C   . ALA A 1 109 ? -5.567  29.892 13.854 1.000 21.852 0 107 ALA AAA C   1 ? 
ATOM   890  O O   . ALA A 1 109 ? -5.844  29.675 12.636 1.000 23.141 0 107 ALA AAA O   1 ? 
ATOM   891  C CB  . ALA A 1 109 ? -6.012  32.330 14.292 1.000 25.397 0 107 ALA AAA CB  1 ? 
ATOM   892  N N   . LYS A 1 110 ? -4.548  29.292 14.495 1.000 20.309 0 108 LYS AAA N   1 ? 
ATOM   893  C CA  . LYS A 1 110 ? -3.626  28.340 13.835 1.000 19.824 0 108 LYS AAA CA  1 ? 
ATOM   894  C C   . LYS A 1 110 ? -4.201  26.926 13.940 1.000 17.418 0 108 LYS AAA C   1 ? 
ATOM   895  O O   . LYS A 1 110 ? -3.500  25.983 14.414 1.000 16.013 0 108 LYS AAA O   1 ? 
ATOM   896  C CB  . LYS A 1 110 ? -2.219  28.423 14.432 1.000 22.992 0 108 LYS AAA CB  1 ? 
ATOM   897  C CG  . LYS A 1 110 ? -1.521  29.773 14.272 1.000 25.050 0 108 LYS AAA CG  1 ? 
ATOM   898  C CD  . LYS A 1 110 ? -1.680  30.345 12.871 1.000 29.434 0 108 LYS AAA CD  1 ? 
ATOM   899  C CE  . LYS A 1 110 ? -0.622  31.365 12.514 1.000 35.788 0 108 LYS AAA CE  1 ? 
ATOM   900  N NZ  . LYS A 1 110 ? -0.788  32.583 13.336 1.000 37.618 0 108 LYS AAA NZ  1 ? 
ATOM   901  N N   . MET A 1 111 ? -5.395  26.750 13.413 1.000 17.627 0 109 MET AAA N   1 ? 
ATOM   902  C CA  . MET A 1 111 ? -6.180  25.511 13.575 1.000 19.872 0 109 MET AAA CA  1 ? 
ATOM   903  C C   . MET A 1 111 ? -7.259  25.492 12.512 1.000 20.572 0 109 MET AAA C   1 ? 
ATOM   904  O O   . MET A 1 111 ? -7.669  26.567 12.062 1.000 22.731 0 109 MET AAA O   1 ? 
ATOM   905  C CB  . MET A 1 111 ? -6.790  25.537 14.974 1.000 21.846 0 109 MET AAA CB  1 ? 
ATOM   906  C CG  . MET A 1 111 ? -7.473  24.338 15.448 1.000 26.632 0 109 MET AAA CG  1 ? 
ATOM   907  S SD  . MET A 1 111 ? -7.697  24.688 17.232 1.000 31.064 0 109 MET AAA SD  1 ? 
ATOM   908  C CE  . MET A 1 111 ? -6.641  23.386 17.843 1.000 28.417 0 109 MET AAA CE  1 ? 
ATOM   909  N N   . TYR A 1 112 ? -7.741  24.312 12.187 1.000 18.585 0 110 TYR AAA N   1 ? 
ATOM   910  C CA  . TYR A 1 112 ? -8.827  24.104 11.209 1.000 19.337 0 110 TYR AAA CA  1 ? 
ATOM   911  C C   . TYR A 1 112 ? -10.033 23.646 12.015 1.000 20.507 0 110 TYR AAA C   1 ? 
ATOM   912  O O   . TYR A 1 112 ? -9.862  23.266 13.191 1.000 23.266 0 110 TYR AAA O   1 ? 
ATOM   913  C CB  . TYR A 1 112 ? -8.393  23.080 10.168 1.000 21.722 0 110 TYR AAA CB  1 ? 
ATOM   914  C CG  . TYR A 1 112 ? -7.203  23.502 9.342  1.000 27.931 0 110 TYR AAA CG  1 ? 
ATOM   915  C CD1 . TYR A 1 112 ? -7.328  24.514 8.408  1.000 30.551 0 110 TYR AAA CD1 1 ? 
ATOM   916  C CD2 . TYR A 1 112 ? -5.966  22.894 9.491  1.000 29.835 0 110 TYR AAA CD2 1 ? 
ATOM   917  C CE1 . TYR A 1 112 ? -6.256  24.915 7.629  1.000 36.101 0 110 TYR AAA CE1 1 ? 
ATOM   918  C CE2 . TYR A 1 112 ? -4.881  23.272 8.703  1.000 32.510 0 110 TYR AAA CE2 1 ? 
ATOM   919  C CZ  . TYR A 1 112 ? -5.030  24.296 7.785  1.000 36.409 0 110 TYR AAA CZ  1 ? 
ATOM   920  O OH  . TYR A 1 112 ? -3.993  24.717 6.993  1.000 48.410 0 110 TYR AAA OH  1 ? 
ATOM   921  N N   . ARG A 1 113 ? -11.172 23.536 11.350 1.000 21.937 0 111 ARG AAA N   1 ? 
ATOM   922  C CA  . ARG A 1 113 ? -12.379 22.968 12.013 1.000 23.640 0 111 ARG AAA CA  1 ? 
ATOM   923  C C   . ARG A 1 113 ? -12.091 21.569 12.560 1.000 25.379 0 111 ARG AAA C   1 ? 
ATOM   924  O O   . ARG A 1 113 ? -11.254 20.816 11.997 1.000 28.751 0 111 ARG AAA O   1 ? 
ATOM   925  C CB  . ARG A 1 113 ? -13.558 23.007 11.046 1.000 25.810 0 111 ARG AAA CB  1 ? 
ATOM   926  C CG  . ARG A 1 113 ? -14.069 24.419 10.817 1.000 26.832 0 111 ARG AAA CG  1 ? 
ATOM   927  C CD  . ARG A 1 113 ? -15.209 24.340 9.806  1.000 29.444 0 111 ARG AAA CD  1 ? 
ATOM   928  N NE  . ARG A 1 113 ? -15.828 25.640 9.597  1.000 29.913 0 111 ARG AAA NE  1 ? 
ATOM   929  C CZ  . ARG A 1 113 ? -15.423 26.549 8.712  1.000 34.861 0 111 ARG AAA CZ  1 ? 
ATOM   930  N NH1 . ARG A 1 113 ? -14.380 26.304 7.934  1.000 39.459 0 111 ARG AAA NH1 1 ? 
ATOM   931  N NH2 . ARG A 1 113 ? -16.081 27.696 8.593  1.000 32.208 0 111 ARG AAA NH2 1 ? 
ATOM   932  N N   . GLY A 1 114 ? -12.631 21.288 13.742 1.000 23.710 0 112 GLY AAA N   1 ? 
ATOM   933  C CA  . GLY A 1 114 ? -12.433 20.001 14.423 1.000 23.601 0 112 GLY AAA CA  1 ? 
ATOM   934  C C   . GLY A 1 114 ? -11.220 20.016 15.324 1.000 23.696 0 112 GLY AAA C   1 ? 
ATOM   935  O O   . GLY A 1 114 ? -10.883 18.968 15.891 1.000 29.232 0 112 GLY AAA O   1 ? 
ATOM   936  N N   . GLY A 1 115 ? -10.502 21.121 15.398 1.000 21.021 0 113 GLY AAA N   1 ? 
ATOM   937  C CA  . GLY A 1 115 ? -9.338  21.226 16.276 1.000 20.912 0 113 GLY AAA CA  1 ? 
ATOM   938  C C   . GLY A 1 115 ? -8.098  20.644 15.611 1.000 18.653 0 113 GLY AAA C   1 ? 
ATOM   939  O O   . GLY A 1 115 ? -7.141  20.360 16.320 1.000 18.065 0 113 GLY AAA O   1 ? 
ATOM   940  N N   . LYS A 1 116 ? -8.086  20.462 14.300 1.000 17.212 0 114 LYS AAA N   1 ? 
ATOM   941  C CA  . LYS A 1 116 ? -6.847  20.019 13.612 1.000 18.280 0 114 LYS AAA CA  1 ? 
ATOM   942  C C   . LYS A 1 116 ? -5.839  21.174 13.615 1.000 16.785 0 114 LYS AAA C   1 ? 
ATOM   943  O O   . LYS A 1 116 ? -6.138  22.225 13.103 1.000 18.133 0 114 LYS AAA O   1 ? 
ATOM   944  C CB  . LYS A 1 116 ? -7.151  19.573 12.193 1.000 20.956 0 114 LYS AAA CB  1 ? 
ATOM   945  C CG  . LYS A 1 116 ? -7.941  18.272 12.165 1.000 24.395 0 114 LYS AAA CG  1 ? 
ATOM   946  C CD  . LYS A 1 116 ? -8.073  17.669 10.789 1.000 29.160 0 114 LYS AAA CD  1 ? 
ATOM   947  C CE  . LYS A 1 116 ? -8.431  16.203 10.840 1.000 31.307 0 114 LYS AAA CE  1 ? 
ATOM   948  N NZ  . LYS A 1 116 ? -8.603  15.681 9.470  1.000 39.047 0 114 LYS AAA NZ  1 ? 
ATOM   949  N N   . ILE A 1 117 ? -4.657  20.951 14.141 1.000 15.739 0 115 ILE AAA N   1 ? 
ATOM   950  C CA  . ILE A 1 117 ? -3.636  22.024 14.246 1.000 14.479 0 115 ILE AAA CA  1 ? 
ATOM   951  C C   . ILE A 1 117 ? -3.111  22.371 12.842 1.000 15.578 0 115 ILE AAA C   1 ? 
ATOM   952  O O   . ILE A 1 117 ? -3.045  21.493 11.963 1.000 15.543 0 115 ILE AAA O   1 ? 
ATOM   953  C CB  . ILE A 1 117 ? -2.524  21.644 15.244 1.000 15.940 0 115 ILE AAA CB  1 ? 
ATOM   954  C CG1 . ILE A 1 117 ? -1.614  20.522 14.723 1.000 16.382 0 115 ILE AAA CG1 1 ? 
ATOM   955  C CG2 . ILE A 1 117 ? -3.091  21.284 16.603 1.000 17.008 0 115 ILE AAA CG2 1 ? 
ATOM   956  C CD1 . ILE A 1 117 ? -0.361  20.232 15.614 1.000 18.432 0 115 ILE AAA CD1 1 ? 
ATOM   957  N N   . GLU A 1 118 ? -2.804  23.653 12.620 1.000 15.616 0 116 GLU AAA N   1 ? 
ATOM   958  C CA  . GLU A 1 118 ? -2.220  24.186 11.389 1.000 17.502 0 116 GLU AAA CA  1 ? 
ATOM   959  C C   . GLU A 1 118 ? -0.779  24.458 11.724 1.000 19.888 0 116 GLU AAA C   1 ? 
ATOM   960  O O   . GLU A 1 118 ? -0.463  25.342 12.595 1.000 19.382 0 116 GLU AAA O   1 ? 
ATOM   961  C CB  . GLU A 1 118 ? -2.921  25.491 11.000 1.000 21.187 0 116 GLU AAA CB  1 ? 
ATOM   962  C CG  . GLU A 1 118 ? -2.404  26.033 9.696  1.000 24.497 0 116 GLU AAA CG  1 ? 
ATOM   963  C CD  . GLU A 1 118 ? -2.870  27.424 9.272  1.000 30.804 0 116 GLU AAA CD  1 ? 
ATOM   964  O OE1 . GLU A 1 118 ? -3.636  28.059 10.032 1.000 32.512 0 116 GLU AAA OE1 1 ? 
ATOM   965  O OE2 . GLU A 1 118 ? -2.455  27.858 8.182  1.000 36.429 0 116 GLU AAA OE2 1 ? 
ATOM   966  N N   . LEU A 1 119 ? 0.077   23.670 11.130 1.000 19.108 0 117 LEU AAA N   1 ? 
ATOM   967  C CA  . LEU A 1 119 ? 1.518   23.942 11.226 1.000 21.661 0 117 LEU AAA CA  1 ? 
ATOM   968  C C   . LEU A 1 119 ? 1.909   24.957 10.167 1.000 22.743 0 117 LEU AAA C   1 ? 
ATOM   969  O O   . LEU A 1 119 ? 1.125   25.280 9.264  1.000 22.844 0 117 LEU AAA O   1 ? 
ATOM   970  C CB  . LEU A 1 119 ? 2.234   22.622 11.015 1.000 19.432 0 117 LEU AAA CB  1 ? 
ATOM   971  C CG  . LEU A 1 119 ? 1.917   21.541 12.021 1.000 21.040 0 117 LEU AAA CG  1 ? 
ATOM   972  C CD1 . LEU A 1 119 ? 2.827   20.337 11.799 1.000 23.837 0 117 LEU AAA CD1 1 ? 
ATOM   973  C CD2 . LEU A 1 119 ? 2.067   22.086 13.447 1.000 21.737 0 117 LEU AAA CD2 1 ? 
ATOM   974  N N   . THR A 1 120 ? 3.136   25.441 10.242 1.000 22.675 0 118 THR AAA N   1 ? 
ATOM   975  C CA  . THR A 1 120 ? 3.681   26.322 9.207  1.000 20.772 0 118 THR AAA CA  1 ? 
ATOM   976  C C   . THR A 1 120 ? 3.925   25.538 7.914  1.000 18.567 0 118 THR AAA C   1 ? 
ATOM   977  O O   . THR A 1 120 ? 4.002   24.278 7.896  1.000 19.090 0 118 THR AAA O   1 ? 
ATOM   978  C CB  . THR A 1 120 ? 4.981   26.999 9.646  1.000 21.814 0 118 THR AAA CB  1 ? 
ATOM   979  O OG1 . THR A 1 120 ? 6.013   26.017 9.600  1.000 23.173 0 118 THR AAA OG1 1 ? 
ATOM   980  C CG2 . THR A 1 120 ? 4.865   27.603 11.029 1.000 23.929 0 118 THR AAA CG2 1 ? 
ATOM   981  N N   . ASP A 1 121 ? 4.078   26.292 6.839  1.000 17.410 0 119 ASP AAA N   1 ? 
ATOM   982  C CA  . ASP A 1 121 ? 4.295   25.704 5.498  1.000 17.977 0 119 ASP AAA CA  1 ? 
ATOM   983  C C   . ASP A 1 121 ? 5.633   25.034 5.370  1.000 19.138 0 119 ASP AAA C   1 ? 
ATOM   984  O O   . ASP A 1 121 ? 5.824   24.376 4.355  1.000 23.016 0 119 ASP AAA O   1 ? 
ATOM   985  C CB  . ASP A 1 121 ? 4.338   26.740 4.385  1.000 20.025 0 119 ASP AAA CB  1 ? 
ATOM   986  C CG  . ASP A 1 121 ? 2.992   27.082 3.843  1.000 24.692 0 119 ASP AAA CG  1 ? 
ATOM   987  O OD1 . ASP A 1 121 ? 2.000   26.435 4.248  1.000 23.614 0 119 ASP AAA OD1 1 ? 
ATOM   988  O OD2 . ASP A 1 121 ? 2.967   28.021 3.002  1.000 24.166 0 119 ASP AAA OD2 1 ? 
ATOM   989  N N   . HIS A 1 122 ? 6.571   25.243 6.277  1.000 15.617 0 120 HIS AAA N   1 ? 
ATOM   990  C CA  . HIS A 1 122 ? 7.850   24.527 6.218  1.000 16.169 0 120 HIS AAA CA  1 ? 
ATOM   991  C C   . HIS A 1 122 ? 7.731   23.063 6.673  1.000 16.615 0 120 HIS AAA C   1 ? 
ATOM   992  O O   . HIS A 1 122 ? 8.573   22.241 6.259  1.000 15.993 0 120 HIS AAA O   1 ? 
ATOM   993  C CB  . HIS A 1 122 ? 8.880   25.333 7.032  1.000 18.165 0 120 HIS AAA CB  1 ? 
ATOM   994  C CG  . HIS A 1 122 ? 9.425   26.492 6.267  1.000 22.817 0 120 HIS AAA CG  1 ? 
ATOM   995  N ND1 . HIS A 1 122 ? 8.759   27.725 6.178  1.000 28.147 0 120 HIS AAA ND1 1 ? 
ATOM   996  C CD2 . HIS A 1 122 ? 10.503  26.575 5.464  1.000 27.866 0 120 HIS AAA CD2 1 ? 
ATOM   997  C CE1 . HIS A 1 122 ? 9.454   28.516 5.387  1.000 30.928 0 120 HIS AAA CE1 1 ? 
ATOM   998  N NE2 . HIS A 1 122 ? 10.535  27.840 4.939  1.000 27.936 0 120 HIS AAA NE2 1 ? 
ATOM   999  N N   . PHE A 1 123 ? 6.739   22.728 7.489  1.000 16.061 0 121 PHE AAA N   1 ? 
ATOM   1000 C CA  . PHE A 1 123 ? 6.630   21.330 7.996  1.000 15.810 0 121 PHE AAA CA  1 ? 
ATOM   1001 C C   . PHE A 1 123 ? 6.401   20.328 6.852  1.000 14.227 0 121 PHE AAA C   1 ? 
ATOM   1002 O O   . PHE A 1 123 ? 7.077   19.275 6.821  1.000 13.715 0 121 PHE AAA O   1 ? 
ATOM   1003 C CB  . PHE A 1 123 ? 5.501   21.178 9.012  1.000 13.709 0 121 PHE AAA CB  1 ? 
ATOM   1004 C CG  . PHE A 1 123 ? 5.433   19.775 9.557  1.000 15.371 0 121 PHE AAA CG  1 ? 
ATOM   1005 C CD1 . PHE A 1 123 ? 6.236   19.373 10.626 1.000 16.046 0 121 PHE AAA CD1 1 ? 
ATOM   1006 C CD2 . PHE A 1 123 ? 4.624   18.822 8.985  1.000 14.353 0 121 PHE AAA CD2 1 ? 
ATOM   1007 C CE1 . PHE A 1 123 ? 6.166   18.070 11.093 1.000 15.885 0 121 PHE AAA CE1 1 ? 
ATOM   1008 C CE2 . PHE A 1 123 ? 4.575   17.524 9.449  1.000 15.252 0 121 PHE AAA CE2 1 ? 
ATOM   1009 C CZ  . PHE A 1 123 ? 5.372   17.142 10.488 1.000 15.971 0 121 PHE AAA CZ  1 ? 
ATOM   1010 N N   . LYS A 1 124 ? 5.471   20.633 5.955  1.000 15.676 0 122 LYS AAA N   1 ? 
ATOM   1011 C CA  . LYS A 1 124 ? 5.054   19.650 4.931  1.000 13.397 0 122 LYS AAA CA  1 ? 
ATOM   1012 C C   . LYS A 1 124 ? 6.226   19.326 4.019  1.000 13.321 0 122 LYS AAA C   1 ? 
ATOM   1013 O O   . LYS A 1 124 ? 6.503   18.120 3.815  1.000 11.795 0 122 LYS AAA O   1 ? 
ATOM   1014 C CB  . LYS A 1 124 ? 3.770   20.099 4.235  1.000 15.229 0 122 LYS AAA CB  1 ? 
ATOM   1015 C CG  . LYS A 1 124 ? 2.516   19.488 4.857  1.000 17.452 0 122 LYS AAA CG  1 ? 
ATOM   1016 C CD  . LYS A 1 124 ? 1.204   20.051 4.329  1.000 19.972 0 122 LYS AAA CD  1 ? 
ATOM   1017 C CE  . LYS A 1 124 ? -0.039  19.469 4.978  1.000 21.800 0 122 LYS AAA CE  1 ? 
ATOM   1018 N NZ  . LYS A 1 124 ? -1.286  20.060 4.473  1.000 23.753 0 122 LYS AAA NZ  1 ? 
ATOM   1019 N N   . PRO A 1 125 ? 6.993   20.283 3.434  1.000 12.505 0 123 PRO AAA N   1 ? 
ATOM   1020 C CA  . PRO A 1 125 ? 8.141   19.903 2.610  1.000 12.012 0 123 PRO AAA CA  1 ? 
ATOM   1021 C C   . PRO A 1 125 ? 9.250   19.181 3.401  1.000 12.233 0 123 PRO AAA C   1 ? 
ATOM   1022 O O   . PRO A 1 125 ? 9.925   18.347 2.870  1.000 13.939 0 123 PRO AAA O   1 ? 
ATOM   1023 C CB  . PRO A 1 125 ? 8.625   21.196 1.948  1.000 13.779 0 123 PRO AAA CB  1 ? 
ATOM   1024 C CG  . PRO A 1 125 ? 7.396   22.070 2.042  1.000 16.564 0 123 PRO AAA CG  1 ? 
ATOM   1025 C CD  . PRO A 1 125 ? 6.678   21.713 3.322  1.000 14.609 0 123 PRO AAA CD  1 ? 
ATOM   1026 N N   . LEU A 1 126 ? 9.372   19.490 4.692  1.000 11.602 0 124 LEU AAA N   1 ? 
ATOM   1027 C CA  . LEU A 1 126 ? 10.368  18.819 5.566  1.000 13.106 0 124 LEU AAA CA  1 ? 
ATOM   1028 C C   . LEU A 1 126 ? 9.945   17.355 5.689  1.000 11.877 0 124 LEU AAA C   1 ? 
ATOM   1029 O O   . LEU A 1 126 ? 10.802  16.463 5.479  1.000 13.025 0 124 LEU AAA O   1 ? 
ATOM   1030 C CB  . LEU A 1 126 ? 10.442  19.475 6.937  1.000 15.093 0 124 LEU AAA CB  1 ? 
ATOM   1031 C CG  . LEU A 1 126 ? 11.283  18.758 7.991  1.000 15.942 0 124 LEU AAA CG  1 ? 
ATOM   1032 C CD1 . LEU A 1 126 ? 12.750  18.671 7.567  1.000 20.038 0 124 LEU AAA CD1 1 ? 
ATOM   1033 C CD2 . LEU A 1 126 ? 11.118  19.458 9.342  1.000 18.671 0 124 LEU AAA CD2 1 ? 
ATOM   1034 N N   . TRP A 1 127 ? 8.689   17.076 5.991  1.000 11.567 0 125 TRP AAA N   1 ? 
ATOM   1035 C CA  . TRP A 1 127 ? 8.209   15.678 6.051  1.000 11.225 0 125 TRP AAA CA  1 ? 
ATOM   1036 C C   . TRP A 1 127 ? 8.448   15.037 4.678  1.000 12.232 0 125 TRP AAA C   1 ? 
ATOM   1037 O O   . TRP A 1 127 ? 9.026   13.928 4.615  1.000 12.510 0 125 TRP AAA O   1 ? 
ATOM   1038 C CB  . TRP A 1 127 ? 6.728   15.693 6.421  1.000 11.841 0 125 TRP AAA CB  1 ? 
ATOM   1039 C CG  . TRP A 1 127 ? 6.128   14.315 6.591  1.000 11.534 0 125 TRP AAA CG  1 ? 
ATOM   1040 C CD1 . TRP A 1 127 ? 5.653   13.522 5.603  1.000 13.226 0 125 TRP AAA CD1 1 ? 
ATOM   1041 C CD2 . TRP A 1 127 ? 6.042   13.535 7.795  1.000 10.597 0 125 TRP AAA CD2 1 ? 
ATOM   1042 N NE1 . TRP A 1 127 ? 5.224   12.334 6.086  1.000 12.930 0 125 TRP AAA NE1 1 ? 
ATOM   1043 C CE2 . TRP A 1 127 ? 5.426   12.311 7.438  1.000 11.405 0 125 TRP AAA CE2 1 ? 
ATOM   1044 C CE3 . TRP A 1 127 ? 6.353   13.766 9.144  1.000 11.163 0 125 TRP AAA CE3 1 ? 
ATOM   1045 C CZ2 . TRP A 1 127 ? 5.139   11.319 8.350  1.000 11.589 0 125 TRP AAA CZ2 1 ? 
ATOM   1046 C CZ3 . TRP A 1 127 ? 6.013   12.807 10.041 1.000 11.402 0 125 TRP AAA CZ3 1 ? 
ATOM   1047 C CH2 . TRP A 1 127 ? 5.484   11.579 9.656  1.000 11.478 0 125 TRP AAA CH2 1 ? 
ATOM   1048 N N   . ALA A 1 128 ? 8.022   15.681 3.587  1.000 12.500 0 126 ALA AAA N   1 ? 
ATOM   1049 C CA  . ALA A 1 128 ? 8.092   15.106 2.230  1.000 12.640 0 126 ALA AAA CA  1 ? 
ATOM   1050 C C   . ALA A 1 128 ? 9.535   14.689 1.909  1.000 13.620 0 126 ALA AAA C   1 ? 
ATOM   1051 O O   . ALA A 1 128 ? 9.723   13.588 1.347  1.000 15.487 0 126 ALA AAA O   1 ? 
ATOM   1052 C CB  . ALA A 1 128 ? 7.528   16.088 1.235  1.000 14.145 0 126 ALA AAA CB  1 ? 
ATOM   1053 N N   . ARG A 1 129 ? 10.495  15.578 2.175  1.000 14.271 0 127 ARG AAA N   1 ? 
ATOM   1054 C CA  . ARG A 1 129 ? 11.917  15.332 1.835  1.000 17.757 0 127 ARG AAA CA  1 ? 
ATOM   1055 C C   . ARG A 1 129 ? 12.446  14.123 2.609  1.000 18.339 0 127 ARG AAA C   1 ? 
ATOM   1056 O O   . ARG A 1 129 ? 13.492  13.570 2.211  1.000 22.585 0 127 ARG AAA O   1 ? 
ATOM   1057 C CB  . ARG A 1 129 ? 12.866  16.478 2.216  1.000 22.522 0 127 ARG AAA CB  1 ? 
ATOM   1058 C CG  . ARG A 1 129 ? 12.719  17.818 1.523  1.000 34.948 0 127 ARG AAA CG  1 ? 
ATOM   1059 C CD  . ARG A 1 129 ? 13.907  18.732 1.892  1.000 37.189 0 127 ARG AAA CD  1 ? 
ATOM   1060 N NE  . ARG A 1 129 ? 14.019  19.288 3.245  1.000 37.009 0 127 ARG AAA NE  1 ? 
ATOM   1061 C CZ  . ARG A 1 129 ? 13.345  20.354 3.705  1.000 36.720 0 127 ARG AAA CZ  1 ? 
ATOM   1062 N NH1 . ARG A 1 129 ? 12.444  20.957 2.956  1.000 34.685 0 127 ARG AAA NH1 1 ? 
ATOM   1063 N NH2 . ARG A 1 129 ? 13.558  20.808 4.932  1.000 41.198 0 127 ARG AAA NH2 1 ? 
ATOM   1064 N N   . ASN A 1 130 ? 11.867  13.806 3.765  1.000 14.192 0 128 ASN AAA N   1 ? 
ATOM   1065 C CA  . ASN A 1 130 ? 12.413  12.716 4.612  1.000 13.796 0 128 ASN AAA CA  1 ? 
ATOM   1066 C C   . ASN A 1 130 ? 11.652  11.392 4.462  1.000 15.507 0 128 ASN AAA C   1 ? 
ATOM   1067 O O   . ASN A 1 130 ? 12.139  10.397 5.119  1.000 17.091 0 128 ASN AAA O   1 ? 
ATOM   1068 C CB  . ASN A 1 130 ? 12.470  13.159 6.076  1.000 14.310 0 128 ASN AAA CB  1 ? 
ATOM   1069 C CG  . ASN A 1 130 ? 13.639  14.068 6.319  1.000 16.426 0 128 ASN AAA CG  1 ? 
ATOM   1070 O OD1 . ASN A 1 130 ? 14.800  13.648 6.409  1.000 18.534 0 128 ASN AAA OD1 1 ? 
ATOM   1071 N ND2 . ASN A 1 130 ? 13.408  15.351 6.312  1.000 16.740 0 128 ASN AAA ND2 1 ? 
ATOM   1072 N N   . VAL A 1 131 ? 10.594  11.289 3.650  1.000 15.089 0 129 VAL AAA N   1 ? 
ATOM   1073 C CA  . VAL A 1 131 ? 9.766   10.058 3.544  1.000 15.724 0 129 VAL AAA CA  1 ? 
ATOM   1074 C C   . VAL A 1 131 ? 10.685  8.913  3.127  1.000 18.354 0 129 VAL AAA C   1 ? 
ATOM   1075 O O   . VAL A 1 131 ? 11.506  9.128  2.205  1.000 19.082 0 129 VAL AAA O   1 ? 
ATOM   1076 C CB  . VAL A 1 131 ? 8.615   10.212 2.550  1.000 16.869 0 129 VAL AAA CB  1 ? 
ATOM   1077 C CG1 . VAL A 1 131 ? 7.944   8.884  2.222  1.000 19.152 0 129 VAL AAA CG1 1 ? 
ATOM   1078 C CG2 . VAL A 1 131 ? 7.592   11.223 3.054  1.000 15.896 0 129 VAL AAA CG2 1 ? 
ATOM   1079 N N   . PRO A 1 132 ? 10.616  7.688  3.722  1.000 15.955 0 130 PRO AAA N   1 ? 
ATOM   1080 C CA  . PRO A 1 132 ? 9.714   7.306  4.831  1.000 14.600 0 130 PRO AAA CA  1 ? 
ATOM   1081 C C   . PRO A 1 132 ? 10.319  7.262  6.236  1.000 14.336 0 130 PRO AAA C   1 ? 
ATOM   1082 O O   . PRO A 1 132 ? 9.845   6.508  7.100  1.000 14.603 0 130 PRO AAA O   1 ? 
ATOM   1083 C CB  . PRO A 1 132 ? 9.335   5.884  4.356  1.000 15.517 0 130 PRO AAA CB  1 ? 
ATOM   1084 C CG  . PRO A 1 132 ? 10.665  5.354  3.935  1.000 15.482 0 130 PRO AAA CG  1 ? 
ATOM   1085 C CD  . PRO A 1 132 ? 11.378  6.506  3.218  1.000 15.854 0 130 PRO AAA CD  1 ? 
ATOM   1086 N N   . LYS A 1 133 ? 11.400  8.015  6.404  1.000 12.052 0 131 LYS AAA N   1 ? 
ATOM   1087 C CA  . LYS A 1 133 ? 12.244  7.974  7.601  1.000 12.954 0 131 LYS AAA CA  1 ? 
ATOM   1088 C C   . LYS A 1 133 ? 11.488  8.541  8.799  1.000 11.978 0 131 LYS AAA C   1 ? 
ATOM   1089 O O   . LYS A 1 133 ? 11.770  8.073  9.918  1.000 14.167 0 131 LYS AAA O   1 ? 
ATOM   1090 C CB  . LYS A 1 133 ? 13.545  8.722  7.362  1.000 14.343 0 131 LYS AAA CB  1 ? 
ATOM   1091 C CG  . LYS A 1 133 ? 14.375  8.041  6.265  1.000 15.218 0 131 LYS AAA CG  1 ? 
ATOM   1092 C CD  . LYS A 1 133 ? 15.708  8.715  6.069  1.000 18.147 0 131 LYS AAA CD  1 ? 
ATOM   1093 C CE  . LYS A 1 133 ? 15.589  10.019 5.286  1.000 20.721 0 131 LYS AAA CE  1 ? 
ATOM   1094 N NZ  . LYS A 1 133 ? 16.929  10.544 4.885  1.000 19.992 0 131 LYS AAA NZ  1 ? 
ATOM   1095 N N   . PHE A 1 134 ? 10.678  9.583  8.632  1.000 11.672 0 132 PHE AAA N   1 ? 
ATOM   1096 C CA  . PHE A 1 134 ? 9.939   10.149 9.796  1.000 11.373 0 132 PHE AAA CA  1 ? 
ATOM   1097 C C   . PHE A 1 134 ? 8.657   9.350  10.016 1.000 9.448  0 132 PHE AAA C   1 ? 
ATOM   1098 O O   . PHE A 1 134 ? 7.977   8.892  9.125  1.000 11.082 0 132 PHE AAA O   1 ? 
ATOM   1099 C CB  . PHE A 1 134 ? 9.618   11.633 9.587  1.000 10.508 0 132 PHE AAA CB  1 ? 
ATOM   1100 C CG  . PHE A 1 134 ? 10.787  12.573 9.593  1.000 11.327 0 132 PHE AAA CG  1 ? 
ATOM   1101 C CD1 . PHE A 1 134 ? 12.083  12.148 9.866  1.000 13.356 0 132 PHE AAA CD1 1 ? 
ATOM   1102 C CD2 . PHE A 1 134 ? 10.566  13.930 9.360  1.000 13.869 0 132 PHE AAA CD2 1 ? 
ATOM   1103 C CE1 . PHE A 1 134 ? 13.137  13.043 9.905  1.000 15.155 0 132 PHE AAA CE1 1 ? 
ATOM   1104 C CE2 . PHE A 1 134 ? 11.632  14.802 9.427  1.000 14.561 0 132 PHE AAA CE2 1 ? 
ATOM   1105 C CZ  . PHE A 1 134 ? 12.895  14.364 9.673  1.000 14.134 0 132 PHE AAA CZ  1 ? 
ATOM   1106 N N   . GLY A 1 135 ? 8.303   9.247  11.318 1.000 10.384 0 133 GLY AAA N   1 ? 
ATOM   1107 C CA  . GLY A 1 135 ? 7.030   8.641  11.756 1.000 11.417 0 133 GLY AAA CA  1 ? 
ATOM   1108 C C   . GLY A 1 135 ? 6.335   9.469  12.818 1.000 10.210 0 133 GLY AAA C   1 ? 
ATOM   1109 O O   . GLY A 1 135 ? 6.600   10.722 12.940 1.000 10.404 0 133 GLY AAA O   1 ? 
ATOM   1110 N N   . LEU A 1 136 ? 5.525   8.813  13.649 1.000 9.614  0 134 LEU AAA N   1 ? 
ATOM   1111 C CA  . LEU A 1 136 ? 4.715   9.566  14.631 1.000 9.714  0 134 LEU AAA CA  1 ? 
ATOM   1112 C C   . LEU A 1 136 ? 5.590   10.258 15.692 1.000 9.823  0 134 LEU AAA C   1 ? 
ATOM   1113 O O   . LEU A 1 136 ? 5.251   11.379 16.103 1.000 10.686 0 134 LEU AAA O   1 ? 
ATOM   1114 C CB  . LEU A 1 136 ? 3.715   8.620  15.275 1.000 10.304 0 134 LEU AAA CB  1 ? 
ATOM   1115 C CG  . LEU A 1 136 ? 2.770   7.916  14.313 1.000 10.837 0 134 LEU AAA CG  1 ? 
ATOM   1116 C CD1 . LEU A 1 136 ? 1.753   7.094  15.051 1.000 12.418 0 134 LEU AAA CD1 1 ? 
ATOM   1117 C CD2 . LEU A 1 136 ? 2.082   8.912  13.393 1.000 11.547 0 134 LEU AAA CD2 1 ? 
ATOM   1118 N N   . ALA A 1 137 ? 6.700   9.678  16.074 1.000 10.185 0 135 ALA AAA N   1 ? 
ATOM   1119 C CA  . ALA A 1 137 ? 7.601   10.373 17.030 1.000 10.499 0 135 ALA AAA CA  1 ? 
ATOM   1120 C C   . ALA A 1 137 ? 8.064   11.706 16.437 1.000 10.695 0 135 ALA AAA C   1 ? 
ATOM   1121 O O   . ALA A 1 137 ? 8.134   12.705 17.172 1.000 10.581 0 135 ALA AAA O   1 ? 
ATOM   1122 C CB  . ALA A 1 137 ? 8.750   9.468  17.399 1.000 10.677 0 135 ALA AAA CB  1 ? 
ATOM   1123 N N   . HIS A 1 138 ? 8.424   11.717 15.163 1.000 10.240 0 136 HIS AAA N   1 ? 
ATOM   1124 C CA  . HIS A 1 138 ? 8.882   12.956 14.480 1.000 10.247 0 136 HIS AAA CA  1 ? 
ATOM   1125 C C   . HIS A 1 138 ? 7.732   13.946 14.335 1.000 9.901  0 136 HIS AAA C   1 ? 
ATOM   1126 O O   . HIS A 1 138 ? 7.951   15.164 14.432 1.000 10.848 0 136 HIS AAA O   1 ? 
ATOM   1127 C CB  . HIS A 1 138 ? 9.474   12.596 13.126 1.000 9.637  0 136 HIS AAA CB  1 ? 
ATOM   1128 C CG  . HIS A 1 138 ? 10.617  11.640 13.190 1.000 10.131 0 136 HIS AAA CG  1 ? 
ATOM   1129 N ND1 . HIS A 1 138 ? 10.427  10.265 13.250 1.000 12.470 0 136 HIS AAA ND1 1 ? 
ATOM   1130 C CD2 . HIS A 1 138 ? 11.948  11.855 13.309 1.000 11.197 0 136 HIS AAA CD2 1 ? 
ATOM   1131 C CE1 . HIS A 1 138 ? 11.626  9.691  13.382 1.000 12.179 0 136 HIS AAA CE1 1 ? 
ATOM   1132 N NE2 . HIS A 1 138 ? 12.582  10.634 13.371 1.000 12.652 0 136 HIS AAA NE2 1 ? 
ATOM   1133 N N   . LEU A 1 139 ? 6.525   13.473 14.051 1.000 9.745  0 137 LEU AAA N   1 ? 
ATOM   1134 C CA  . LEU A 1 139 ? 5.329   14.324 13.951 1.000 10.286 0 137 LEU AAA CA  1 ? 
ATOM   1135 C C   . LEU A 1 139 ? 5.147   15.040 15.286 1.000 10.254 0 137 LEU AAA C   1 ? 
ATOM   1136 O O   . LEU A 1 139 ? 4.815   16.263 15.297 1.000 11.613 0 137 LEU AAA O   1 ? 
ATOM   1137 C CB  . LEU A 1 139 ? 4.110   13.466 13.590 1.000 11.293 0 137 LEU AAA CB  1 ? 
ATOM   1138 C CG  . LEU A 1 139 ? 2.799   14.219 13.445 1.000 12.523 0 137 LEU AAA CG  1 ? 
ATOM   1139 C CD1 . LEU A 1 139 ? 2.823   15.079 12.186 1.000 15.908 0 137 LEU AAA CD1 1 ? 
ATOM   1140 C CD2 . LEU A 1 139 ? 1.618   13.269 13.414 1.000 13.736 0 137 LEU AAA CD2 1 ? 
ATOM   1141 N N   . MET A 1 140 ? 5.298   14.336 16.393 1.000 9.972  0 138 MET AAA N   1 ? 
ATOM   1142 C CA  . MET A 1 140 ? 5.172   14.973 17.701 1.000 9.806  0 138 MET AAA CA  1 ? 
ATOM   1143 C C   . MET A 1 140 ? 6.347   15.954 17.936 1.000 9.946  0 138 MET AAA C   1 ? 
ATOM   1144 O O   . MET A 1 140 ? 6.092   17.078 18.316 1.000 10.166 0 138 MET AAA O   1 ? 
ATOM   1145 C CB  . MET A 1 140 ? 5.173   13.899 18.779 1.000 10.765 0 138 MET AAA CB  1 ? 
ATOM   1146 C CG  . MET A 1 140 ? 3.950   12.957 18.729 1.000 11.760 0 138 MET AAA CG  1 ? 
ATOM   1147 S SD  . MET A 1 140 ? 2.369   13.777 19.049 1.000 12.276 0 138 MET AAA SD  1 ? 
ATOM   1148 C CE  . MET A 1 140 ? 2.433   13.820 20.822 1.000 12.643 0 138 MET AAA CE  1 ? 
ATOM   1149 N N   . ALA A 1 141 ? 7.577   15.515 17.727 1.000 9.693  0 139 ALA AAA N   1 ? 
ATOM   1150 C CA  . ALA A 1 141 ? 8.768   16.370 18.007 1.000 9.579  0 139 ALA AAA CA  1 ? 
ATOM   1151 C C   . ALA A 1 141 ? 8.793   17.646 17.144 1.000 10.744 0 139 ALA AAA C   1 ? 
ATOM   1152 O O   . ALA A 1 141 ? 9.231   18.714 17.654 1.000 11.795 0 139 ALA AAA O   1 ? 
ATOM   1153 C CB  . ALA A 1 141 ? 10.015  15.521 17.839 1.000 10.635 0 139 ALA AAA CB  1 ? 
ATOM   1154 N N   . LEU A 1 142 ? 8.510   17.534 15.857 1.000 10.049 0 140 LEU AAA N   1 ? 
ATOM   1155 C CA  . LEU A 1 142 ? 8.660   18.613 14.855 1.000 10.781 0 140 LEU AAA CA  1 ? 
ATOM   1156 C C   . LEU A 1 142 ? 7.329   19.330 14.569 1.000 11.410 0 140 LEU AAA C   1 ? 
ATOM   1157 O O   . LEU A 1 142 ? 7.399   20.434 13.944 1.000 13.740 0 140 LEU AAA O   1 ? 
ATOM   1158 C CB  . LEU A 1 142 ? 9.220   18.048 13.557 1.000 11.146 0 140 LEU AAA CB  1 ? 
ATOM   1159 C CG  . LEU A 1 142 ? 10.651  17.507 13.623 1.000 10.945 0 140 LEU AAA CG  1 ? 
ATOM   1160 C CD1 . LEU A 1 142 ? 10.978  16.669 12.372 1.000 12.248 0 140 LEU AAA CD1 1 ? 
ATOM   1161 C CD2 . LEU A 1 142 ? 11.662  18.646 13.808 1.000 13.165 0 140 LEU AAA CD2 1 ? 
ATOM   1162 N N   . GLY A 1 143 ? 6.187   18.724 14.885 1.000 10.212 0 141 GLY AAA N   1 ? 
ATOM   1163 C CA  . GLY A 1 143 ? 4.891   19.330 14.539 1.000 10.372 0 141 GLY AAA CA  1 ? 
ATOM   1164 C C   . GLY A 1 143 ? 4.188   19.830 15.777 1.000 11.877 0 141 GLY AAA C   1 ? 
ATOM   1165 O O   . GLY A 1 143 ? 4.115   21.065 16.003 1.000 13.508 0 141 GLY AAA O   1 ? 
ATOM   1166 N N   . LEU A 1 144 ? 3.668   18.915 16.605 1.000 11.181 0 142 LEU AAA N   1 ? 
ATOM   1167 C CA  . LEU A 1 144 ? 2.861   19.332 17.775 1.000 10.982 0 142 LEU AAA CA  1 ? 
ATOM   1168 C C   . LEU A 1 144 ? 3.726   20.085 18.775 1.000 11.868 0 142 LEU AAA C   1 ? 
ATOM   1169 O O   . LEU A 1 144 ? 3.231   21.073 19.367 1.000 11.419 0 142 LEU AAA O   1 ? 
ATOM   1170 C CB  . LEU A 1 144 ? 2.128   18.143 18.386 1.000 12.034 0 142 LEU AAA CB  1 ? 
ATOM   1171 C CG  . LEU A 1 144 ? 1.332   18.394 19.681 1.000 11.451 0 142 LEU AAA CG  1 ? 
ATOM   1172 C CD1 . LEU A 1 144 ? 0.172   19.347 19.417 1.000 12.069 0 142 LEU AAA CD1 1 ? 
ATOM   1173 C CD2 . LEU A 1 144 ? 0.788   17.079 20.260 1.000 12.112 0 142 LEU AAA CD2 1 ? 
ATOM   1174 N N   . GLY A 1 145 ? 4.934   19.634 19.062 1.000 11.080 0 143 GLY AAA N   1 ? 
ATOM   1175 C CA  . GLY A 1 145 ? 5.730   20.229 20.165 1.000 11.469 0 143 GLY AAA CA  1 ? 
ATOM   1176 C C   . GLY A 1 145 ? 5.946   21.726 19.949 1.000 12.031 0 143 GLY AAA C   1 ? 
ATOM   1177 O O   . GLY A 1 145 ? 5.610   22.509 20.840 1.000 13.674 0 143 GLY AAA O   1 ? 
ATOM   1178 N N   . PRO A 1 146 ? 6.446   22.185 18.779 1.000 12.190 0 144 PRO AAA N   1 ? 
ATOM   1179 C CA  . PRO A 1 146 ? 6.588   23.636 18.526 1.000 12.082 0 144 PRO AAA CA  1 ? 
ATOM   1180 C C   . PRO A 1 146 ? 5.260   24.353 18.403 1.000 12.846 0 144 PRO AAA C   1 ? 
ATOM   1181 O O   . PRO A 1 146 ? 5.222   25.550 18.684 1.000 14.562 0 144 PRO AAA O   1 ? 
ATOM   1182 C CB  . PRO A 1 146 ? 7.486   23.732 17.285 1.000 15.509 0 144 PRO AAA CB  1 ? 
ATOM   1183 C CG  . PRO A 1 146 ? 7.519   22.371 16.706 1.000 15.510 0 144 PRO AAA CG  1 ? 
ATOM   1184 C CD  . PRO A 1 146 ? 7.065   21.347 17.726 1.000 13.352 0 144 PRO AAA CD  1 ? 
ATOM   1185 N N   . TRP A 1 147 ? 4.203   23.705 17.960 1.000 10.951 0 145 TRP AAA N   1 ? 
ATOM   1186 C CA  . TRP A 1 147 ? 2.869   24.330 17.892 1.000 12.006 0 145 TRP AAA CA  1 ? 
ATOM   1187 C C   . TRP A 1 147 ? 2.441   24.695 19.311 1.000 11.167 0 145 TRP AAA C   1 ? 
ATOM   1188 O O   . TRP A 1 147 ? 2.029   25.847 19.542 1.000 12.644 0 145 TRP AAA O   1 ? 
ATOM   1189 C CB  . TRP A 1 147 ? 1.836   23.416 17.212 1.000 12.556 0 145 TRP AAA CB  1 ? 
ATOM   1190 C CG  . TRP A 1 147 ? 0.484   24.029 16.990 1.000 12.560 0 145 TRP AAA CG  1 ? 
ATOM   1191 C CD1 . TRP A 1 147 ? 0.049   24.699 15.882 1.000 12.903 0 145 TRP AAA CD1 1 ? 
ATOM   1192 C CD2 . TRP A 1 147 ? -0.630  23.974 17.885 1.000 13.553 0 145 TRP AAA CD2 1 ? 
ATOM   1193 N NE1 . TRP A 1 147 ? -1.252  25.104 16.055 1.000 14.496 0 145 TRP AAA NE1 1 ? 
ATOM   1194 C CE2 . TRP A 1 147 ? -1.689  24.711 17.286 1.000 12.752 0 145 TRP AAA CE2 1 ? 
ATOM   1195 C CE3 . TRP A 1 147 ? -0.817  23.482 19.181 1.000 14.273 0 145 TRP AAA CE3 1 ? 
ATOM   1196 C CZ2 . TRP A 1 147 ? -2.935  24.872 17.894 1.000 15.830 0 145 TRP AAA CZ2 1 ? 
ATOM   1197 C CZ3 . TRP A 1 147 ? -2.055  23.631 19.784 1.000 16.608 0 145 TRP AAA CZ3 1 ? 
ATOM   1198 C CH2 . TRP A 1 147 ? -3.083  24.349 19.151 1.000 16.829 0 145 TRP AAA CH2 1 ? 
ATOM   1199 N N   . LEU A 1 148 ? 2.547   23.791 20.255 1.000 11.215 0 146 LEU AAA N   1 ? 
ATOM   1200 C CA  . LEU A 1 148 ? 2.172   24.070 21.654 1.000 11.105 0 146 LEU AAA CA  1 ? 
ATOM   1201 C C   . LEU A 1 148 ? 2.994   25.250 22.203 1.000 12.508 0 146 LEU AAA C   1 ? 
ATOM   1202 O O   . LEU A 1 148 ? 2.419   26.087 22.910 1.000 13.556 0 146 LEU AAA O   1 ? 
ATOM   1203 C CB  . LEU A 1 148 ? 2.368   22.837 22.530 1.000 12.333 0 146 LEU AAA CB  1 ? 
ATOM   1204 C CG  . LEU A 1 148 ? 1.454   21.642 22.277 1.000 12.535 0 146 LEU AAA CG  1 ? 
ATOM   1205 C CD1 . LEU A 1 148 ? 1.978   20.461 23.048 1.000 12.226 0 146 LEU AAA CD1 1 ? 
ATOM   1206 C CD2 . LEU A 1 148 ? 0.012   21.937 22.614 1.000 12.653 0 146 LEU AAA CD2 1 ? 
ATOM   1207 N N   . ALA A 1 149 ? 4.298   25.270 21.915 1.000 12.099 0 147 ALA AAA N   1 ? 
ATOM   1208 C CA  . ALA A 1 149 ? 5.228   26.285 22.463 1.000 12.100 0 147 ALA AAA CA  1 ? 
ATOM   1209 C C   . ALA A 1 149 ? 4.904   27.690 21.962 1.000 13.016 0 147 ALA AAA C   1 ? 
ATOM   1210 O O   . ALA A 1 149 ? 5.439   28.666 22.559 1.000 12.840 0 147 ALA AAA O   1 ? 
ATOM   1211 C CB  . ALA A 1 149 ? 6.654   25.872 22.231 1.000 13.503 0 147 ALA AAA CB  1 ? 
ATOM   1212 N N   . VAL A 1 150 ? 4.141   27.820 20.885 1.000 11.433 0 148 VAL AAA N   1 ? 
ATOM   1213 C CA  . VAL A 1 150 ? 3.617   29.128 20.438 1.000 12.498 0 148 VAL AAA CA  1 ? 
ATOM   1214 C C   . VAL A 1 150 ? 2.200   29.321 20.969 1.000 14.071 0 148 VAL AAA C   1 ? 
ATOM   1215 O O   . VAL A 1 150 ? 1.878   30.394 21.586 1.000 15.811 0 148 VAL AAA O   1 ? 
ATOM   1216 C CB  . VAL A 1 150 ? 3.726   29.298 18.909 1.000 12.700 0 148 VAL AAA CB  1 ? 
ATOM   1217 C CG1 . VAL A 1 150 ? 3.026   30.566 18.484 1.000 12.992 0 148 VAL AAA CG1 1 ? 
ATOM   1218 C CG2 . VAL A 1 150 ? 5.157   29.305 18.422 1.000 13.803 0 148 VAL AAA CG2 1 ? 
ATOM   1219 N N   . GLU A 1 151 ? 1.298   28.391 20.680 1.000 12.669 0 149 GLU AAA N   1 ? 
ATOM   1220 C CA  . GLU A 1 151 ? -0.150  28.605 20.824 1.000 13.353 0 149 GLU AAA CA  1 ? 
ATOM   1221 C C   . GLU A 1 151 ? -0.547  28.561 22.301 1.000 13.969 0 149 GLU AAA C   1 ? 
ATOM   1222 O O   . GLU A 1 151 ? -1.425  29.362 22.671 1.000 15.496 0 149 GLU AAA O   1 ? 
ATOM   1223 C CB  . GLU A 1 151 ? -0.899  27.579 19.986 1.000 15.581 0 149 GLU AAA CB  1 ? 
ATOM   1224 C CG  . GLU A 1 151 ? -0.676  27.753 18.495 1.000 15.731 0 149 GLU AAA CG  1 ? 
ATOM   1225 C CD  . GLU A 1 151 ? -0.948  29.134 17.958 1.000 19.274 0 149 GLU AAA CD  1 ? 
ATOM   1226 O OE1 . GLU A 1 151 ? -2.039  29.671 18.301 1.000 22.692 0 149 GLU AAA OE1 1 ? 
ATOM   1227 O OE2 . GLU A 1 151 ? -0.105  29.664 17.187 1.000 22.340 0 149 GLU AAA OE2 1 ? 
ATOM   1228 N N   . ILE A 1 152 ? -0.035  27.658 23.116 1.000 13.510 0 150 ILE AAA N   1 ? 
ATOM   1229 C CA  . ILE A 1 152 ? -0.479  27.560 24.538 1.000 14.078 0 150 ILE AAA CA  1 ? 
ATOM   1230 C C   . ILE A 1 152 ? -0.116  28.840 25.303 1.000 15.149 0 150 ILE AAA C   1 ? 
ATOM   1231 O O   . ILE A 1 152 ? -1.011  29.363 25.985 1.000 15.018 0 150 ILE AAA O   1 ? 
ATOM   1232 C CB  . ILE A 1 152 ? -0.080  26.250 25.235 1.000 14.510 0 150 ILE AAA CB  1 ? 
ATOM   1233 C CG1 . ILE A 1 152 ? -0.503  25.021 24.411 1.000 14.582 0 150 ILE AAA CG1 1 ? 
ATOM   1234 C CG2 . ILE A 1 152 ? -0.679  26.222 26.640 1.000 15.085 0 150 ILE AAA CG2 1 ? 
ATOM   1235 C CD1 . ILE A 1 152 ? -1.963  25.006 23.984 1.000 14.906 0 150 ILE AAA CD1 1 ? 
ATOM   1236 N N   . PRO A 1 153 ? 1.118   29.379 25.249 1.000 14.856 0 151 PRO AAA N   1 ? 
ATOM   1237 C CA  . PRO A 1 153 ? 1.367   30.654 25.923 1.000 15.562 0 151 PRO AAA CA  1 ? 
ATOM   1238 C C   . PRO A 1 153 ? 0.430   31.744 25.406 1.000 16.005 0 151 PRO AAA C   1 ? 
ATOM   1239 O O   . PRO A 1 153 ? -0.012  32.587 26.248 1.000 17.245 0 151 PRO AAA O   1 ? 
ATOM   1240 C CB  . PRO A 1 153 ? 2.840   30.931 25.586 1.000 15.247 0 151 PRO AAA CB  1 ? 
ATOM   1241 C CG  . PRO A 1 153 ? 3.443   29.560 25.365 1.000 14.782 0 151 PRO AAA CG  1 ? 
ATOM   1242 C CD  . PRO A 1 153 ? 2.347   28.766 24.696 1.000 13.957 0 151 PRO AAA CD  1 ? 
ATOM   1243 N N   . ASP A 1 154 ? 0.170   31.823 24.106 1.000 15.155 0 152 ASP AAA N   1 ? 
ATOM   1244 C CA  . ASP A 1 154 ? -0.683  32.882 23.503 1.000 18.682 0 152 ASP AAA CA  1 ? 
ATOM   1245 C C   . ASP A 1 154 ? -2.091  32.787 24.100 1.000 21.967 0 152 ASP AAA C   1 ? 
ATOM   1246 O O   . ASP A 1 154 ? -2.661  33.821 24.543 1.000 21.185 0 152 ASP AAA O   1 ? 
ATOM   1247 C CB  . ASP A 1 154 ? -0.688  32.798 21.980 1.000 20.822 0 152 ASP AAA CB  1 ? 
ATOM   1248 C CG  . ASP A 1 154 ? -1.411  33.965 21.336 1.000 25.940 0 152 ASP AAA CG  1 ? 
ATOM   1249 O OD1 . ASP A 1 154 ? -1.134  35.101 21.742 1.000 29.121 0 152 ASP AAA OD1 1 ? 
ATOM   1250 O OD2 . ASP A 1 154 ? -2.207  33.737 20.430 1.000 26.992 0 152 ASP AAA OD2 1 ? 
ATOM   1251 N N   . LEU A 1 155 ? -2.650  31.590 24.146 1.000 17.437 0 153 LEU AAA N   1 ? 
ATOM   1252 C CA  . LEU A 1 155 ? -4.058  31.404 24.597 1.000 18.420 0 153 LEU AAA CA  1 ? 
ATOM   1253 C C   . LEU A 1 155 ? -4.159  31.662 26.095 1.000 17.664 0 153 LEU AAA C   1 ? 
ATOM   1254 O O   . LEU A 1 155 ? -5.190  32.176 26.542 1.000 18.918 0 153 LEU AAA O   1 ? 
ATOM   1255 C CB  . LEU A 1 155 ? -4.527  29.998 24.211 1.000 19.457 0 153 LEU AAA CB  1 ? 
ATOM   1256 C CG  . LEU A 1 155 ? -4.798  29.792 22.725 1.000 23.673 0 153 LEU AAA CG  1 ? 
ATOM   1257 C CD1 . LEU A 1 155 ? -5.200  28.350 22.456 1.000 23.413 0 153 LEU AAA CD1 1 ? 
ATOM   1258 C CD2 . LEU A 1 155 ? -5.835  30.750 22.225 1.000 28.754 0 153 LEU AAA CD2 1 ? 
ATOM   1259 N N   . ILE A 1 156 ? -3.157  31.328 26.874 1.000 16.609 0 154 ILE AAA N   1 ? 
ATOM   1260 C CA  . ILE A 1 156 ? -3.141  31.665 28.335 1.000 17.296 0 154 ILE AAA CA  1 ? 
ATOM   1261 C C   . ILE A 1 156 ? -3.088  33.195 28.487 1.000 19.610 0 154 ILE AAA C   1 ? 
ATOM   1262 O O   . ILE A 1 156 ? -3.944  33.766 29.226 1.000 20.061 0 154 ILE AAA O   1 ? 
ATOM   1263 C CB  . ILE A 1 156 ? -1.972  30.977 29.043 1.000 18.602 0 154 ILE AAA CB  1 ? 
ATOM   1264 C CG1 . ILE A 1 156 ? -2.191  29.468 29.089 1.000 15.765 0 154 ILE AAA CG1 1 ? 
ATOM   1265 C CG2 . ILE A 1 156 ? -1.756  31.540 30.432 1.000 17.933 0 154 ILE AAA CG2 1 ? 
ATOM   1266 C CD1 . ILE A 1 156 ? -1.002  28.677 29.474 1.000 16.604 0 154 ILE AAA CD1 1 ? 
ATOM   1267 N N   . GLN A 1 157 ? -2.215  33.870 27.757 1.000 21.019 0 155 GLN AAA N   1 ? 
ATOM   1268 C CA  . GLN A 1 157 ? -2.122  35.362 27.872 1.000 21.980 0 155 GLN AAA CA  1 ? 
ATOM   1269 C C   . GLN A 1 157 ? -3.469  35.996 27.500 1.000 23.010 0 155 GLN AAA C   1 ? 
ATOM   1270 O O   . GLN A 1 157 ? -3.849  37.016 28.108 1.000 24.499 0 155 GLN AAA O   1 ? 
ATOM   1271 C CB  . GLN A 1 157 ? -1.025  35.917 26.958 1.000 22.640 0 155 GLN AAA CB  1 ? 
ATOM   1272 C CG  . GLN A 1 157 ? -0.741  37.406 27.166 1.000 26.154 0 155 GLN AAA CG  1 ? 
ATOM   1273 C CD  . GLN A 1 157 ? -1.672  38.325 26.410 1.000 29.814 0 155 GLN AAA CD  1 ? 
ATOM   1274 O OE1 . GLN A 1 157 ? -2.023  38.104 25.252 1.000 31.517 0 155 GLN AAA OE1 1 ? 
ATOM   1275 N N   . LYS A 1 158 ? -4.146  35.499 26.482 1.000 20.588 0 156 LYS AAA N   1 ? 
ATOM   1276 C CA  . LYS A 1 158 ? -5.410  36.065 25.942 1.000 22.277 0 156 LYS AAA CA  1 ? 
ATOM   1277 C C   . LYS A 1 158 ? -6.616  35.706 26.830 1.000 24.079 0 156 LYS AAA C   1 ? 
ATOM   1278 O O   . LYS A 1 158 ? -7.710  36.225 26.526 1.000 25.335 0 156 LYS AAA O   1 ? 
ATOM   1279 C CB  . LYS A 1 158 ? -5.617  35.590 24.510 1.000 25.082 0 156 LYS AAA CB  1 ? 
ATOM   1280 C CG  . LYS A 1 158 ? -4.727  36.300 23.512 1.000 26.988 0 156 LYS AAA CG  1 ? 
ATOM   1281 C CD  . LYS A 1 158 ? -4.904  35.850 22.103 1.000 29.346 0 156 LYS AAA CD  1 ? 
ATOM   1282 C CE  . LYS A 1 158 ? -4.030  36.642 21.158 1.000 30.863 0 156 LYS AAA CE  1 ? 
ATOM   1283 N NZ  . LYS A 1 158 ? -3.881  35.921 19.874 1.000 36.477 0 156 LYS AAA NZ  1 ? 
ATOM   1284 N N   . GLY A 1 159 ? -6.423  34.926 27.891 1.000 22.686 0 157 GLY AAA N   1 ? 
ATOM   1285 C CA  . GLY A 1 159 ? -7.477  34.474 28.817 1.000 23.702 0 157 GLY AAA CA  1 ? 
ATOM   1286 C C   . GLY A 1 159 ? -8.416  33.455 28.169 1.000 27.061 0 157 GLY AAA C   1 ? 
ATOM   1287 O O   . GLY A 1 159 ? -9.505  33.273 28.703 1.000 27.545 0 157 GLY AAA O   1 ? 
ATOM   1288 N N   . VAL A 1 160 ? -7.990  32.745 27.124 1.000 24.531 0 158 VAL AAA N   1 ? 
ATOM   1289 C CA  . VAL A 1 160 ? -8.845  31.752 26.400 1.000 24.447 0 158 VAL AAA CA  1 ? 
ATOM   1290 C C   . VAL A 1 160 ? -8.774  30.402 27.121 1.000 25.718 0 158 VAL AAA C   1 ? 
ATOM   1291 O O   . VAL A 1 160 ? -9.795  29.661 27.107 1.000 31.200 0 158 VAL AAA O   1 ? 
ATOM   1292 C CB  . VAL A 1 160 ? -8.392  31.642 24.925 1.000 27.528 0 158 VAL AAA CB  1 ? 
ATOM   1293 C CG1 . VAL A 1 160 ? -9.123  30.545 24.157 1.000 29.673 0 158 VAL AAA CG1 1 ? 
ATOM   1294 C CG2 . VAL A 1 160 ? -8.546  32.946 24.195 1.000 27.474 0 158 VAL AAA CG2 1 ? 
ATOM   1295 N N   . ILE A 1 161 ? -7.629  30.037 27.679 1.000 21.833 0 159 ILE AAA N   1 ? 
ATOM   1296 C CA  . ILE A 1 161 ? -7.381  28.786 28.443 1.000 28.112 0 159 ILE AAA CA  1 ? 
ATOM   1297 C C   . ILE A 1 161 ? -7.148  29.192 29.898 1.000 27.268 0 159 ILE AAA C   1 ? 
ATOM   1298 O O   . ILE A 1 161 ? -6.428  30.189 30.123 1.000 27.702 0 159 ILE AAA O   1 ? 
ATOM   1299 C CB  . ILE A 1 161 ? -6.158  28.011 27.882 1.000 33.767 0 159 ILE AAA CB  1 ? 
ATOM   1300 C CG1 . ILE A 1 161 ? -5.522  27.072 28.903 1.000 37.560 0 159 ILE AAA CG1 1 ? 
ATOM   1301 C CG2 . ILE A 1 161 ? -5.120  28.959 27.337 1.000 42.647 0 159 ILE AAA CG2 1 ? 
ATOM   1302 C CD1 . ILE A 1 161 ? -4.220  26.480 28.455 1.000 43.616 0 159 ILE AAA CD1 1 ? 
ATOM   1303 N N   . HIS A 1 162 ? -7.679  28.396 30.817 1.000 25.984 0 160 HIS AAA N   1 ? 
ATOM   1304 C CA  . HIS A 1 162 ? -7.494  28.512 32.281 1.000 27.783 0 160 HIS AAA CA  1 ? 
ATOM   1305 C C   . HIS A 1 162 ? -6.934  27.192 32.800 1.000 27.240 0 160 HIS AAA C   1 ? 
ATOM   1306 O O   . HIS A 1 162 ? -7.153  26.172 32.154 1.000 29.355 0 160 HIS AAA O   1 ? 
ATOM   1307 C CB  . HIS A 1 162 ? -8.845  28.892 32.899 1.000 31.133 0 160 HIS AAA CB  1 ? 
ATOM   1308 C CG  . HIS A 1 162 ? -9.471  30.043 32.193 1.000 33.685 0 160 HIS AAA CG  1 ? 
ATOM   1309 N ND1 . HIS A 1 162 ? -9.058  31.339 32.419 1.000 38.770 0 160 HIS AAA ND1 1 ? 
ATOM   1310 C CD2 . HIS A 1 162 ? -10.396 30.101 31.209 1.000 37.525 0 160 HIS AAA CD2 1 ? 
ATOM   1311 C CE1 . HIS A 1 162 ? -9.747  32.156 31.650 1.000 38.504 0 160 HIS AAA CE1 1 ? 
ATOM   1312 N NE2 . HIS A 1 162 ? -10.580 31.419 30.901 1.000 42.082 0 160 HIS AAA NE2 1 ? 
ATOM   1313 N N   . HIS A 1 163 ? -6.236  27.202 33.934 1.000 25.025 0 161 HIS AAA N   1 ? 
ATOM   1314 C CA  . HIS A 1 163 ? -5.607  25.994 34.532 1.000 25.370 0 161 HIS AAA CA  1 ? 
ATOM   1315 C C   . HIS A 1 163 ? -6.647  25.174 35.304 1.000 29.556 0 161 HIS AAA C   1 ? 
ATOM   1316 O O   . HIS A 1 163 ? -7.289  25.878 36.066 1.000 34.152 0 161 HIS AAA O   1 ? 
ATOM   1317 C CB  . HIS A 1 163 ? -4.369  26.407 35.363 1.000 22.457 0 161 HIS AAA CB  1 ? 
ATOM   1318 C CG  . HIS A 1 163 ? -3.673  25.241 35.955 1.000 23.517 0 161 HIS AAA CG  1 ? 
ATOM   1319 N ND1 . HIS A 1 163 ? -2.875  24.347 35.229 1.000 22.373 0 161 HIS AAA ND1 1 ? 
ATOM   1320 C CD2 . HIS A 1 163 ? -3.727  24.761 37.203 1.000 20.079 0 161 HIS AAA CD2 1 ? 
ATOM   1321 C CE1 . HIS A 1 163 ? -2.448  23.417 36.042 1.000 20.424 0 161 HIS AAA CE1 1 ? 
ATOM   1322 N NE2 . HIS A 1 163 ? -2.987  23.634 37.238 1.000 25.026 0 161 HIS AAA NE2 1 ? 
HETATM 1323 C C1  . GOL B 2 .   ? 7.436   19.892 25.029 1.000 27.560 0 201 GOL AAA C1  1 ? 
HETATM 1324 O O1  . GOL B 2 .   ? 8.052   19.633 23.774 1.000 32.060 0 201 GOL AAA O1  1 ? 
HETATM 1325 C C2  . GOL B 2 .   ? 6.107   20.516 24.709 1.000 31.954 0 201 GOL AAA C2  1 ? 
HETATM 1326 O O2  . GOL B 2 .   ? 5.199   20.516 25.855 1.000 24.564 0 201 GOL AAA O2  1 ? 
HETATM 1327 C C3  . GOL B 2 .   ? 6.424   21.855 24.045 1.000 27.612 0 201 GOL AAA C3  1 ? 
HETATM 1328 O O3  . GOL B 2 .   ? 5.414   22.255 23.160 1.000 34.000 0 201 GOL AAA O3  1 ? 
HETATM 1329 C C1  . GOL C 2 .   ? 12.067  18.133 21.646 1.000 28.916 0 202 GOL AAA C1  1 ? 
HETATM 1330 O O1  . GOL C 2 .   ? 11.591  16.821 21.800 1.000 20.421 0 202 GOL AAA O1  1 ? 
HETATM 1331 C C2  . GOL C 2 .   ? 10.854  18.887 22.062 1.000 32.206 0 202 GOL AAA C2  1 ? 
HETATM 1332 O O2  . GOL C 2 .   ? 11.236  19.811 23.077 1.000 22.582 0 202 GOL AAA O2  1 ? 
HETATM 1333 C C3  . GOL C 2 .   ? 10.011  19.240 20.844 1.000 24.714 0 202 GOL AAA C3  1 ? 
HETATM 1334 O O3  . GOL C 2 .   ? 9.065   20.272 21.025 1.000 23.795 0 202 GOL AAA O3  1 ? 
HETATM 1335 C C1  . GOL D 2 .   ? 0.636   17.924 10.052 1.000 31.920 0 203 GOL AAA C1  1 ? 
HETATM 1336 O O1  . GOL D 2 .   ? 0.624   17.942 8.595  1.000 31.495 0 203 GOL AAA O1  1 ? 
HETATM 1337 C C2  . GOL D 2 .   ? -0.681  17.547 10.757 1.000 35.960 0 203 GOL AAA C2  1 ? 
HETATM 1338 O O2  . GOL D 2 .   ? -0.498  17.044 12.127 1.000 23.164 0 203 GOL AAA O2  1 ? 
HETATM 1339 C C3  . GOL D 2 .   ? -1.744  18.643 10.636 1.000 30.950 0 203 GOL AAA C3  1 ? 
HETATM 1340 O O3  . GOL D 2 .   ? -2.696  18.799 11.729 1.000 32.879 0 203 GOL AAA O3  1 ? 
HETATM 1341 S S   . SO4 E 3 .   ? -11.513 24.185 7.504  1.000 43.428 0 204 SO4 AAA S   1 ? 
HETATM 1342 O O1  . SO4 E 3 .   ? -10.751 24.873 6.483  1.000 45.388 0 204 SO4 AAA O1  1 ? 
HETATM 1343 O O2  . SO4 E 3 .   ? -11.257 24.841 8.762  1.000 34.525 0 204 SO4 AAA O2  1 ? 
HETATM 1344 O O3  . SO4 E 3 .   ? -12.923 24.249 7.183  1.000 44.821 0 204 SO4 AAA O3  1 ? 
HETATM 1345 O O4  . SO4 E 3 .   ? -11.141 22.810 7.588  1.000 37.795 0 204 SO4 AAA O4  1 ? 
HETATM 1346 O O   . HOH F 4 .   ? 6.914   5.769  1.507  1.000 25.554 0 301 HOH AAA O   1 ? 
HETATM 1347 O O   . HOH F 4 .   ? -9.799  6.603  12.659 1.000 47.593 0 302 HOH AAA O   1 ? 
HETATM 1348 O O   . HOH F 4 .   ? 15.308  4.151  26.425 1.000 24.807 0 303 HOH AAA O   1 ? 
HETATM 1349 O O   . HOH F 4 .   ? -10.823 7.150  10.554 1.000 39.204 0 304 HOH AAA O   1 ? 
HETATM 1350 O O   . HOH F 4 .   ? 11.305  0.246  27.003 1.000 39.081 0 305 HOH AAA O   1 ? 
HETATM 1351 O O   . HOH F 4 .   ? 20.193  9.424  14.174 1.000 21.950 0 306 HOH AAA O   1 ? 
HETATM 1352 O O   . HOH F 4 .   ? -9.457  -0.323 12.779 1.000 21.780 0 307 HOH AAA O   1 ? 
HETATM 1353 O O   . HOH F 4 .   ? 21.315  8.013  21.291 1.000 43.568 0 308 HOH AAA O   1 ? 
HETATM 1354 O O   . HOH F 4 .   ? 3.759   34.787 31.920 1.000 32.895 0 309 HOH AAA O   1 ? 
HETATM 1355 O O   . HOH F 4 .   ? -15.667 21.932 14.689 1.000 33.840 0 310 HOH AAA O   1 ? 
HETATM 1356 O O   . HOH F 4 .   ? -0.398  36.764 23.617 1.000 31.082 0 311 HOH AAA O   1 ? 
HETATM 1357 O O   . HOH F 4 .   ? 19.893  25.839 12.762 1.000 27.263 0 312 HOH AAA O   1 ? 
HETATM 1358 O O   . HOH F 4 .   ? 2.892   22.426 6.399  1.000 21.171 0 313 HOH AAA O   1 ? 
HETATM 1359 O O   . HOH F 4 .   ? 7.497   11.075 33.723 1.000 28.383 0 314 HOH AAA O   1 ? 
HETATM 1360 O O   . HOH F 4 .   ? 12.604  7.748  0.242  1.000 23.670 0 315 HOH AAA O   1 ? 
HETATM 1361 O O   . HOH F 4 .   ? -0.004  32.221 16.535 1.000 30.943 0 316 HOH AAA O   1 ? 
HETATM 1362 O O   . HOH F 4 .   ? 12.857  11.306 1.005  1.000 34.699 0 317 HOH AAA O   1 ? 
HETATM 1363 O O   . HOH F 4 .   ? 11.984  2.137  2.502  1.000 36.090 0 318 HOH AAA O   1 ? 
HETATM 1364 O O   . HOH F 4 .   ? 7.800   25.783 25.649 1.000 30.418 0 319 HOH AAA O   1 ? 
HETATM 1365 O O   . HOH F 4 .   ? -7.011  5.036  8.691  1.000 39.696 0 320 HOH AAA O   1 ? 
HETATM 1366 O O   . HOH F 4 .   ? -8.593  17.974 23.508 1.000 24.596 0 321 HOH AAA O   1 ? 
HETATM 1367 O O   . HOH F 4 .   ? 10.673  22.885 4.773  1.000 29.077 0 322 HOH AAA O   1 ? 
HETATM 1368 O O   . HOH F 4 .   ? 14.181  7.798  30.771 1.000 31.839 0 323 HOH AAA O   1 ? 
HETATM 1369 O O   . HOH F 4 .   ? 20.288  17.118 20.005 1.000 26.286 0 324 HOH AAA O   1 ? 
HETATM 1370 O O   . HOH F 4 .   ? -0.871  16.584 6.843  1.000 23.953 0 325 HOH AAA O   1 ? 
HETATM 1371 O O   . HOH F 4 .   ? -1.191  1.544  22.028 1.000 18.212 0 326 HOH AAA O   1 ? 
HETATM 1372 O O   . HOH F 4 .   ? 13.233  20.837 33.123 1.000 24.411 0 327 HOH AAA O   1 ? 
HETATM 1373 O O   . HOH F 4 .   ? 1.829   28.596 15.647 1.000 24.274 0 328 HOH AAA O   1 ? 
HETATM 1374 O O   . HOH F 4 .   ? 22.858  19.115 20.727 1.000 34.507 0 329 HOH AAA O   1 ? 
HETATM 1375 O O   . HOH F 4 .   ? -8.790  1.257  10.191 1.000 30.072 0 330 HOH AAA O   1 ? 
HETATM 1376 O O   . HOH F 4 .   ? -14.443 25.347 15.072 1.000 29.057 0 331 HOH AAA O   1 ? 
HETATM 1377 O O   . HOH F 4 .   ? 15.418  10.518 13.768 1.000 16.987 0 332 HOH AAA O   1 ? 
HETATM 1378 O O   . HOH F 4 .   ? 12.635  -2.464 18.928 1.000 18.133 0 333 HOH AAA O   1 ? 
HETATM 1379 O O   . HOH F 4 .   ? 15.122  4.489  6.565  1.000 20.278 0 334 HOH AAA O   1 ? 
HETATM 1380 O O   . HOH F 4 .   ? 23.286  19.448 9.737  1.000 31.653 0 335 HOH AAA O   1 ? 
HETATM 1381 O O   . HOH F 4 .   ? 10.225  -3.455 5.518  1.000 15.493 0 336 HOH AAA O   1 ? 
HETATM 1382 O O   . HOH F 4 .   ? 11.454  -6.736 11.590 1.000 16.152 0 337 HOH AAA O   1 ? 
HETATM 1383 O O   . HOH F 4 .   ? 7.367   -7.775 11.158 1.000 16.569 0 338 HOH AAA O   1 ? 
HETATM 1384 O O   . HOH F 4 .   ? -3.293  13.869 6.241  1.000 34.500 0 339 HOH AAA O   1 ? 
HETATM 1385 O O   . HOH F 4 .   ? -4.788  12.327 9.627  1.000 19.730 0 340 HOH AAA O   1 ? 
HETATM 1386 O O   . HOH F 4 .   ? -3.623  -4.004 6.415  1.000 20.534 0 341 HOH AAA O   1 ? 
HETATM 1387 O O   . HOH F 4 .   ? 7.068   6.772  15.584 1.000 12.619 0 342 HOH AAA O   1 ? 
HETATM 1388 O O   . HOH F 4 .   ? 18.297  10.796 7.267  1.000 40.169 0 343 HOH AAA O   1 ? 
HETATM 1389 O O   . HOH F 4 .   ? 23.460  21.811 8.133  1.000 35.291 0 344 HOH AAA O   1 ? 
HETATM 1390 O O   . HOH F 4 .   ? -5.168  32.446 17.861 1.000 45.396 0 345 HOH AAA O   1 ? 
HETATM 1391 O O   . HOH F 4 .   ? 0.434   29.564 33.459 1.000 17.850 0 346 HOH AAA O   1 ? 
HETATM 1392 O O   . HOH F 4 .   ? -2.571  1.857  3.059  1.000 19.955 0 347 HOH AAA O   1 ? 
HETATM 1393 O O   . HOH F 4 .   ? 12.088  2.825  13.933 1.000 16.555 0 348 HOH AAA O   1 ? 
HETATM 1394 O O   . HOH F 4 .   ? -5.595  32.610 31.182 1.000 30.318 0 349 HOH AAA O   1 ? 
HETATM 1395 O O   . HOH F 4 .   ? -6.734  13.023 12.057 1.000 19.892 0 350 HOH AAA O   1 ? 
HETATM 1396 O O   . HOH F 4 .   ? 3.330   21.755 37.647 1.000 31.875 0 351 HOH AAA O   1 ? 
HETATM 1397 O O   . HOH F 4 .   ? -13.586 31.132 17.367 1.000 38.464 0 352 HOH AAA O   1 ? 
HETATM 1398 O O   . HOH F 4 .   ? 14.031  13.717 23.945 1.000 20.467 0 353 HOH AAA O   1 ? 
HETATM 1399 O O   . HOH F 4 .   ? 0.556   2.878  23.766 1.000 19.166 0 354 HOH AAA O   1 ? 
HETATM 1400 O O   . HOH F 4 .   ? 5.144   -8.199 9.555  1.000 16.156 0 355 HOH AAA O   1 ? 
HETATM 1401 O O   . HOH F 4 .   ? 15.997  12.490 2.749  1.000 33.187 0 356 HOH AAA O   1 ? 
HETATM 1402 O O   . HOH F 4 .   ? 4.366   0.952  -1.615 1.000 38.354 0 357 HOH AAA O   1 ? 
HETATM 1403 O O   . HOH F 4 .   ? 13.619  22.138 11.370 1.000 29.505 0 358 HOH AAA O   1 ? 
HETATM 1404 O O   . HOH F 4 .   ? 6.964   11.951 26.316 1.000 15.544 0 359 HOH AAA O   1 ? 
HETATM 1405 O O   . HOH F 4 .   ? 5.753   28.373 28.395 1.000 24.117 0 360 HOH AAA O   1 ? 
HETATM 1406 O O   . HOH F 4 .   ? 17.426  12.655 27.140 1.000 23.522 0 361 HOH AAA O   1 ? 
HETATM 1407 O O   . HOH F 4 .   ? 3.100   28.906 7.081  1.000 34.350 0 362 HOH AAA O   1 ? 
HETATM 1408 O O   . HOH F 4 .   ? -3.065  -0.842 21.277 1.000 27.250 0 363 HOH AAA O   1 ? 
HETATM 1409 O O   . HOH F 4 .   ? 10.304  18.500 0.087  1.000 20.567 0 364 HOH AAA O   1 ? 
HETATM 1410 O O   . HOH F 4 .   ? -7.619  11.700 23.223 1.000 35.860 0 365 HOH AAA O   1 ? 
HETATM 1411 O O   . HOH F 4 .   ? 6.134   23.131 38.586 1.000 37.051 0 366 HOH AAA O   1 ? 
HETATM 1412 O O   . HOH F 4 .   ? 9.579   0.021  2.215  1.000 18.261 0 367 HOH AAA O   1 ? 
HETATM 1413 O O   . HOH F 4 .   ? 9.615   21.614 12.664 1.000 24.518 0 368 HOH AAA O   1 ? 
HETATM 1414 O O   . HOH F 4 .   ? -4.915  -1.818 9.345  1.000 26.568 0 369 HOH AAA O   1 ? 
HETATM 1415 O O   . HOH F 4 .   ? -6.668  1.240  22.346 1.000 25.983 0 370 HOH AAA O   1 ? 
HETATM 1416 O O   . HOH F 4 .   ? 16.695  13.365 19.399 1.000 28.455 0 371 HOH AAA O   1 ? 
HETATM 1417 O O   . HOH F 4 .   ? 7.568   9.464  6.377  1.000 14.117 0 372 HOH AAA O   1 ? 
HETATM 1418 O O   . HOH F 4 .   ? 0.643   32.063 34.324 1.000 34.525 0 373 HOH AAA O   1 ? 
HETATM 1419 O O   . HOH F 4 .   ? 0.994   23.945 5.203  1.000 23.423 0 374 HOH AAA O   1 ? 
HETATM 1420 O O   . HOH F 4 .   ? 9.529   22.059 23.513 1.000 29.288 0 375 HOH AAA O   1 ? 
HETATM 1421 O O   . HOH F 4 .   ? 7.472   26.843 33.553 1.000 26.493 0 376 HOH AAA O   1 ? 
HETATM 1422 O O   . HOH F 4 .   ? 3.772   -0.887 0.340  1.000 30.772 0 377 HOH AAA O   1 ? 
HETATM 1423 O O   . HOH F 4 .   ? -8.089  8.579  16.805 1.000 27.599 0 378 HOH AAA O   1 ? 
HETATM 1424 O O   . HOH F 4 .   ? -13.032 14.973 18.035 1.000 32.998 0 379 HOH AAA O   1 ? 
HETATM 1425 O O   . HOH F 4 .   ? 9.244   11.686 6.399  1.000 17.682 0 380 HOH AAA O   1 ? 
HETATM 1426 O O   . HOH F 4 .   ? -0.820  22.050 8.932  1.000 25.383 0 381 HOH AAA O   1 ? 
HETATM 1427 O O   . HOH F 4 .   ? 14.767  12.232 21.657 1.000 21.384 0 382 HOH AAA O   1 ? 
HETATM 1428 O O   . HOH F 4 .   ? 13.086  1.537  21.029 1.000 16.639 0 383 HOH AAA O   1 ? 
HETATM 1429 O O   . HOH F 4 .   ? 15.734  20.035 7.095  1.000 30.523 0 384 HOH AAA O   1 ? 
HETATM 1430 O O   . HOH F 4 .   ? 2.875   -4.175 14.864 1.000 26.230 0 385 HOH AAA O   1 ? 
HETATM 1431 O O   . HOH F 4 .   ? 6.093   22.161 28.409 1.000 22.453 0 386 HOH AAA O   1 ? 
HETATM 1432 O O   . HOH F 4 .   ? 7.392   28.925 31.867 1.000 22.381 0 387 HOH AAA O   1 ? 
HETATM 1433 O O   . HOH F 4 .   ? 18.314  17.302 8.804  1.000 27.636 0 388 HOH AAA O   1 ? 
HETATM 1434 O O   . HOH F 4 .   ? 10.907  13.230 33.711 1.000 30.115 0 389 HOH AAA O   1 ? 
HETATM 1435 O O   . HOH F 4 .   ? -5.603  29.817 35.113 1.000 42.233 0 390 HOH AAA O   1 ? 
HETATM 1436 O O   . HOH F 4 .   ? -6.730  8.704  3.904  1.000 28.735 0 391 HOH AAA O   1 ? 
HETATM 1437 O O   . HOH F 4 .   ? 1.419   -2.774 -0.208 1.000 29.754 0 392 HOH AAA O   1 ? 
HETATM 1438 O O   . HOH F 4 .   ? -8.491  -1.470 15.252 1.000 16.997 0 393 HOH AAA O   1 ? 
HETATM 1439 O O   . HOH F 4 .   ? 1.244   20.809 8.055  1.000 25.403 0 394 HOH AAA O   1 ? 
HETATM 1440 O O   . HOH F 4 .   ? -10.626 25.701 14.754 1.000 28.479 0 395 HOH AAA O   1 ? 
HETATM 1441 O O   . HOH F 4 .   ? 9.031   15.336 32.747 1.000 22.660 0 396 HOH AAA O   1 ? 
HETATM 1442 O O   . HOH F 4 .   ? -11.060 17.392 8.920  1.000 47.745 0 397 HOH AAA O   1 ? 
HETATM 1443 O O   . HOH F 4 .   ? 15.800  17.201 6.752  1.000 29.596 0 398 HOH AAA O   1 ? 
HETATM 1444 O O   . HOH F 4 .   ? 13.267  -1.631 9.877  1.000 28.454 0 399 HOH AAA O   1 ? 
HETATM 1445 O O   . HOH F 4 .   ? 0.545   15.721 4.529  1.000 21.884 0 400 HOH AAA O   1 ? 
HETATM 1446 O O   . HOH F 4 .   ? -2.131  -4.965 8.873  1.000 32.577 0 401 HOH AAA O   1 ? 
HETATM 1447 O O   . HOH F 4 .   ? -6.945  24.284 29.677 1.000 38.557 0 402 HOH AAA O   1 ? 
HETATM 1448 O O   . HOH F 4 .   ? 18.319  27.107 6.183  1.000 34.524 0 403 HOH AAA O   1 ? 
HETATM 1449 O O   . HOH F 4 .   ? 7.336   33.542 34.770 1.000 26.369 0 404 HOH AAA O   1 ? 
HETATM 1450 O O   . HOH F 4 .   ? 13.868  21.960 14.154 1.000 17.241 0 405 HOH AAA O   1 ? 
HETATM 1451 O O   . HOH F 4 .   ? 5.589   23.076 13.542 1.000 45.940 0 406 HOH AAA O   1 ? 
HETATM 1452 O O   . HOH F 4 .   ? 8.339   31.126 33.601 1.000 22.998 0 407 HOH AAA O   1 ? 
HETATM 1453 O O   . HOH F 4 .   ? -1.574  -4.550 13.693 1.000 38.013 0 408 HOH AAA O   1 ? 
HETATM 1454 O O   . HOH F 4 .   ? -7.393  -0.900 8.419  1.000 44.024 0 409 HOH AAA O   1 ? 
HETATM 1455 O O   . HOH F 4 .   ? -2.524  19.860 8.246  1.000 33.008 0 410 HOH AAA O   1 ? 
HETATM 1456 O O   . HOH F 4 .   ? 19.995  2.106  21.646 1.000 23.150 0 411 HOH AAA O   1 ? 
HETATM 1457 O O   . HOH F 4 .   ? 9.225   22.938 10.194 1.000 37.206 0 412 HOH AAA O   1 ? 
HETATM 1458 O O   . HOH F 4 .   ? -8.997  12.649 13.233 1.000 43.461 0 413 HOH AAA O   1 ? 
HETATM 1459 O O   . HOH F 4 .   ? 10.390  24.674 2.487  1.000 33.429 0 414 HOH AAA O   1 ? 
HETATM 1460 O O   . HOH F 4 .   ? 18.767  13.341 12.266 1.000 29.672 0 415 HOH AAA O   1 ? 
HETATM 1461 O O   . HOH F 4 .   ? 1.578   29.107 11.033 1.000 35.979 0 416 HOH AAA O   1 ? 
HETATM 1462 O O   . HOH F 4 .   ? 17.864  10.913 12.391 1.000 30.802 0 417 HOH AAA O   1 ? 
HETATM 1463 O O   . HOH F 4 .   ? 11.275  22.361 14.920 1.000 17.878 0 418 HOH AAA O   1 ? 
# 
