data_9GL0
# 
_entry.id   9GL0 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GL0         pdb_00009gl0 10.2210/pdb9gl0/pdb 
WWPDB D_1292141036 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2024-11-13 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.country'                 
2 2 'Structure model' '_citation.journal_abbrev'          
3 2 'Structure model' '_citation.journal_id_ISSN'         
4 2 'Structure model' '_citation.journal_volume'          
5 2 'Structure model' '_citation.page_first'              
6 2 'Structure model' '_citation.page_last'               
7 2 'Structure model' '_citation.pdbx_database_id_DOI'    
8 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
9 2 'Structure model' '_citation.title'                   
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GL0 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              michael.lammers@uni-greifswald.de 
_pdbx_contact_author.name_first         Michael 
_pdbx_contact_author.name_last          Lammers 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4168-4640 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Graf, L.G.'  1 0009-0007-7269-1743 
'Schulze, S.' 2 0000-0002-0122-5688 
'Palm, G.J.'  3 0000-0003-0329-0413 
'Lammers, M.' 4 0000-0003-4168-4640 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                9496 
_citation.page_last                 9496 
_citation.title                     'Distribution and diversity of classical deacylases in bacteria.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-53903-0 
_citation.pdbx_database_id_PubMed   39489725 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Graf, L.G.'        1  0009-0007-7269-1743 
primary 'Moreno-Yruela, C.' 2  0000-0003-2450-6519 
primary 'Qin, C.'           3  ?                   
primary 'Schulze, S.'       4  0000-0002-0122-5688 
primary 'Palm, G.J.'        5  0000-0003-0329-0413 
primary 'Schmoker, O.'      6  ?                   
primary 'Wang, N.'          7  0000-0001-7623-1858 
primary 'Hocking, D.M.'     8  0000-0002-3485-0586 
primary 'Jebeli, L.'        9  0000-0003-4240-9528 
primary 'Girbardt, B.'      10 ?                   
primary 'Berndt, L.'        11 ?                   
primary 'Dorre, B.'         12 ?                   
primary 'Weis, D.M.'        13 ?                   
primary 'Janetzky, M.'      14 ?                   
primary 'Albrecht, D.'      15 ?                   
primary 'Zuhlke, D.'        16 ?                   
primary 'Sievers, S.'       17 0000-0002-5457-2552 
primary 'Strugnell, R.A.'   18 0000-0003-0614-5641 
primary 'Olsen, C.A.'       19 0000-0002-2953-8942 
primary 'Hofmann, K.'       20 0000-0002-2289-9083 
primary 'Lammers, M.'       21 0000-0003-4168-4640 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Acetylpolyamine aminohydrolase' 50256.191 4  ? ? ? 'His6-tagged fusion-protein' 
2 non-polymer syn 'ZINC ION'                       65.409    4  ? ? ? ?                            
3 non-polymer syn 'POTASSIUM ION'                  39.098    2  ? ? ? ?                            
4 water       nat water                            18.015    18 ? ? ? ?                            
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAHHHHHHVGTMDMAKDKGFFKKAKMEKNKRLVTPYSEECAIQIPSEIDNEQMQRMPAGGEEDQYLRIKHMSALIKKYGD
LPVITTQETRLPYYWLDLFAAIDEGDTPKAHALFHLLPQDDIILRALRAVHSEDYLYQLIKYCIQAKHFGFKQLNADLVV
TPKTFEILIRDCATTLFNPAKAHFSFGLPSHHAYTQMGSGFCLINKTAMLMKQAELSSAQPPKFVIIGTDVNRDNGLCDI
LRHSFSHLSICHIDVFDSRVYPQQDFAYINNEFNSEGVDIGKNIHVWHHNNLNYYAVDLSLTSRKSVGVHPALLFALEQL
KESIREAKAKGQKIALYLPTGWDSHEDETAYCGKFVNGRMMGKTAAHQFRFNDGDLGYFYESIFTLYNENKDCVDTIYWG
LEGGYDRTMYERELKILLQVIEKQLLPKDSNSHSMSY
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAHHHHHHVGTMDMAKDKGFFKKAKMEKNKRLVTPYSEECAIQIPSEIDNEQMQRMPAGGEEDQYLRIKHMSALIKKYGD
LPVITTQETRLPYYWLDLFAAIDEGDTPKAHALFHLLPQDDIILRALRAVHSEDYLYQLIKYCIQAKHFGFKQLNADLVV
TPKTFEILIRDCATTLFNPAKAHFSFGLPSHHAYTQMGSGFCLINKTAMLMKQAELSSAQPPKFVIIGTDVNRDNGLCDI
LRHSFSHLSICHIDVFDSRVYPQQDFAYINNEFNSEGVDIGKNIHVWHHNNLNYYAVDLSLTSRKSVGVHPALLFALEQL
KESIREAKAKGQKIALYLPTGWDSHEDETAYCGKFVNGRMMGKTAAHQFRFNDGDLGYFYESIFTLYNENKDCVDTIYWG
LEGGYDRTMYERELKILLQVIEKQLLPKDSNSHSMSY
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'ZINC ION'      ZN  
3 'POTASSIUM ION' K   
4 water           HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   HIS n 
1 4   HIS n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   VAL n 
1 10  GLY n 
1 11  THR n 
1 12  MET n 
1 13  ASP n 
1 14  MET n 
1 15  ALA n 
1 16  LYS n 
1 17  ASP n 
1 18  LYS n 
1 19  GLY n 
1 20  PHE n 
1 21  PHE n 
1 22  LYS n 
1 23  LYS n 
1 24  ALA n 
1 25  LYS n 
1 26  MET n 
1 27  GLU n 
1 28  LYS n 
1 29  ASN n 
1 30  LYS n 
1 31  ARG n 
1 32  LEU n 
1 33  VAL n 
1 34  THR n 
1 35  PRO n 
1 36  TYR n 
1 37  SER n 
1 38  GLU n 
1 39  GLU n 
1 40  CYS n 
1 41  ALA n 
1 42  ILE n 
1 43  GLN n 
1 44  ILE n 
1 45  PRO n 
1 46  SER n 
1 47  GLU n 
1 48  ILE n 
1 49  ASP n 
1 50  ASN n 
1 51  GLU n 
1 52  GLN n 
1 53  MET n 
1 54  GLN n 
1 55  ARG n 
1 56  MET n 
1 57  PRO n 
1 58  ALA n 
1 59  GLY n 
1 60  GLY n 
1 61  GLU n 
1 62  GLU n 
1 63  ASP n 
1 64  GLN n 
1 65  TYR n 
1 66  LEU n 
1 67  ARG n 
1 68  ILE n 
1 69  LYS n 
1 70  HIS n 
1 71  MET n 
1 72  SER n 
1 73  ALA n 
1 74  LEU n 
1 75  ILE n 
1 76  LYS n 
1 77  LYS n 
1 78  TYR n 
1 79  GLY n 
1 80  ASP n 
1 81  LEU n 
1 82  PRO n 
1 83  VAL n 
1 84  ILE n 
1 85  THR n 
1 86  THR n 
1 87  GLN n 
1 88  GLU n 
1 89  THR n 
1 90  ARG n 
1 91  LEU n 
1 92  PRO n 
1 93  TYR n 
1 94  TYR n 
1 95  TRP n 
1 96  LEU n 
1 97  ASP n 
1 98  LEU n 
1 99  PHE n 
1 100 ALA n 
1 101 ALA n 
1 102 ILE n 
1 103 ASP n 
1 104 GLU n 
1 105 GLY n 
1 106 ASP n 
1 107 THR n 
1 108 PRO n 
1 109 LYS n 
1 110 ALA n 
1 111 HIS n 
1 112 ALA n 
1 113 LEU n 
1 114 PHE n 
1 115 HIS n 
1 116 LEU n 
1 117 LEU n 
1 118 PRO n 
1 119 GLN n 
1 120 ASP n 
1 121 ASP n 
1 122 ILE n 
1 123 ILE n 
1 124 LEU n 
1 125 ARG n 
1 126 ALA n 
1 127 LEU n 
1 128 ARG n 
1 129 ALA n 
1 130 VAL n 
1 131 HIS n 
1 132 SER n 
1 133 GLU n 
1 134 ASP n 
1 135 TYR n 
1 136 LEU n 
1 137 TYR n 
1 138 GLN n 
1 139 LEU n 
1 140 ILE n 
1 141 LYS n 
1 142 TYR n 
1 143 CYS n 
1 144 ILE n 
1 145 GLN n 
1 146 ALA n 
1 147 LYS n 
1 148 HIS n 
1 149 PHE n 
1 150 GLY n 
1 151 PHE n 
1 152 LYS n 
1 153 GLN n 
1 154 LEU n 
1 155 ASN n 
1 156 ALA n 
1 157 ASP n 
1 158 LEU n 
1 159 VAL n 
1 160 VAL n 
1 161 THR n 
1 162 PRO n 
1 163 LYS n 
1 164 THR n 
1 165 PHE n 
1 166 GLU n 
1 167 ILE n 
1 168 LEU n 
1 169 ILE n 
1 170 ARG n 
1 171 ASP n 
1 172 CYS n 
1 173 ALA n 
1 174 THR n 
1 175 THR n 
1 176 LEU n 
1 177 PHE n 
1 178 ASN n 
1 179 PRO n 
1 180 ALA n 
1 181 LYS n 
1 182 ALA n 
1 183 HIS n 
1 184 PHE n 
1 185 SER n 
1 186 PHE n 
1 187 GLY n 
1 188 LEU n 
1 189 PRO n 
1 190 SER n 
1 191 HIS n 
1 192 HIS n 
1 193 ALA n 
1 194 TYR n 
1 195 THR n 
1 196 GLN n 
1 197 MET n 
1 198 GLY n 
1 199 SER n 
1 200 GLY n 
1 201 PHE n 
1 202 CYS n 
1 203 LEU n 
1 204 ILE n 
1 205 ASN n 
1 206 LYS n 
1 207 THR n 
1 208 ALA n 
1 209 MET n 
1 210 LEU n 
1 211 MET n 
1 212 LYS n 
1 213 GLN n 
1 214 ALA n 
1 215 GLU n 
1 216 LEU n 
1 217 SER n 
1 218 SER n 
1 219 ALA n 
1 220 GLN n 
1 221 PRO n 
1 222 PRO n 
1 223 LYS n 
1 224 PHE n 
1 225 VAL n 
1 226 ILE n 
1 227 ILE n 
1 228 GLY n 
1 229 THR n 
1 230 ASP n 
1 231 VAL n 
1 232 ASN n 
1 233 ARG n 
1 234 ASP n 
1 235 ASN n 
1 236 GLY n 
1 237 LEU n 
1 238 CYS n 
1 239 ASP n 
1 240 ILE n 
1 241 LEU n 
1 242 ARG n 
1 243 HIS n 
1 244 SER n 
1 245 PHE n 
1 246 SER n 
1 247 HIS n 
1 248 LEU n 
1 249 SER n 
1 250 ILE n 
1 251 CYS n 
1 252 HIS n 
1 253 ILE n 
1 254 ASP n 
1 255 VAL n 
1 256 PHE n 
1 257 ASP n 
1 258 SER n 
1 259 ARG n 
1 260 VAL n 
1 261 TYR n 
1 262 PRO n 
1 263 GLN n 
1 264 GLN n 
1 265 ASP n 
1 266 PHE n 
1 267 ALA n 
1 268 TYR n 
1 269 ILE n 
1 270 ASN n 
1 271 ASN n 
1 272 GLU n 
1 273 PHE n 
1 274 ASN n 
1 275 SER n 
1 276 GLU n 
1 277 GLY n 
1 278 VAL n 
1 279 ASP n 
1 280 ILE n 
1 281 GLY n 
1 282 LYS n 
1 283 ASN n 
1 284 ILE n 
1 285 HIS n 
1 286 VAL n 
1 287 TRP n 
1 288 HIS n 
1 289 HIS n 
1 290 ASN n 
1 291 ASN n 
1 292 LEU n 
1 293 ASN n 
1 294 TYR n 
1 295 TYR n 
1 296 ALA n 
1 297 VAL n 
1 298 ASP n 
1 299 LEU n 
1 300 SER n 
1 301 LEU n 
1 302 THR n 
1 303 SER n 
1 304 ARG n 
1 305 LYS n 
1 306 SER n 
1 307 VAL n 
1 308 GLY n 
1 309 VAL n 
1 310 HIS n 
1 311 PRO n 
1 312 ALA n 
1 313 LEU n 
1 314 LEU n 
1 315 PHE n 
1 316 ALA n 
1 317 LEU n 
1 318 GLU n 
1 319 GLN n 
1 320 LEU n 
1 321 LYS n 
1 322 GLU n 
1 323 SER n 
1 324 ILE n 
1 325 ARG n 
1 326 GLU n 
1 327 ALA n 
1 328 LYS n 
1 329 ALA n 
1 330 LYS n 
1 331 GLY n 
1 332 GLN n 
1 333 LYS n 
1 334 ILE n 
1 335 ALA n 
1 336 LEU n 
1 337 TYR n 
1 338 LEU n 
1 339 PRO n 
1 340 THR n 
1 341 GLY n 
1 342 TRP n 
1 343 ASP n 
1 344 SER n 
1 345 HIS n 
1 346 GLU n 
1 347 ASP n 
1 348 GLU n 
1 349 THR n 
1 350 ALA n 
1 351 TYR n 
1 352 CYS n 
1 353 GLY n 
1 354 LYS n 
1 355 PHE n 
1 356 VAL n 
1 357 ASN n 
1 358 GLY n 
1 359 ARG n 
1 360 MET n 
1 361 MET n 
1 362 GLY n 
1 363 LYS n 
1 364 THR n 
1 365 ALA n 
1 366 ALA n 
1 367 HIS n 
1 368 GLN n 
1 369 PHE n 
1 370 ARG n 
1 371 PHE n 
1 372 ASN n 
1 373 ASP n 
1 374 GLY n 
1 375 ASP n 
1 376 LEU n 
1 377 GLY n 
1 378 TYR n 
1 379 PHE n 
1 380 TYR n 
1 381 GLU n 
1 382 SER n 
1 383 ILE n 
1 384 PHE n 
1 385 THR n 
1 386 LEU n 
1 387 TYR n 
1 388 ASN n 
1 389 GLU n 
1 390 ASN n 
1 391 LYS n 
1 392 ASP n 
1 393 CYS n 
1 394 VAL n 
1 395 ASP n 
1 396 THR n 
1 397 ILE n 
1 398 TYR n 
1 399 TRP n 
1 400 GLY n 
1 401 LEU n 
1 402 GLU n 
1 403 GLY n 
1 404 GLY n 
1 405 TYR n 
1 406 ASP n 
1 407 ARG n 
1 408 THR n 
1 409 MET n 
1 410 TYR n 
1 411 GLU n 
1 412 ARG n 
1 413 GLU n 
1 414 LEU n 
1 415 LYS n 
1 416 ILE n 
1 417 LEU n 
1 418 LEU n 
1 419 GLN n 
1 420 VAL n 
1 421 ILE n 
1 422 GLU n 
1 423 LYS n 
1 424 GLN n 
1 425 LEU n 
1 426 LEU n 
1 427 PRO n 
1 428 LYS n 
1 429 ASP n 
1 430 SER n 
1 431 ASN n 
1 432 SER n 
1 433 HIS n 
1 434 SER n 
1 435 MET n 
1 436 SER n 
1 437 TYR n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   437 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 C3928_11280 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    LG61 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Legionella pneumophila' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     446 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          Plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       'pET-45b(+)' 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
K   non-polymer         . 'POTASSIUM ION' ? 'K 1'            39.098  
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
ZN  non-polymer         . 'ZINC ION'      ? 'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -10 ?   ?   ?   A . n 
A 1 2   ALA 2   -9  ?   ?   ?   A . n 
A 1 3   HIS 3   -8  ?   ?   ?   A . n 
A 1 4   HIS 4   -7  ?   ?   ?   A . n 
A 1 5   HIS 5   -6  ?   ?   ?   A . n 
A 1 6   HIS 6   -5  ?   ?   ?   A . n 
A 1 7   HIS 7   -4  ?   ?   ?   A . n 
A 1 8   HIS 8   -3  ?   ?   ?   A . n 
A 1 9   VAL 9   -2  ?   ?   ?   A . n 
A 1 10  GLY 10  -1  ?   ?   ?   A . n 
A 1 11  THR 11  0   ?   ?   ?   A . n 
A 1 12  MET 12  1   ?   ?   ?   A . n 
A 1 13  ASP 13  2   ?   ?   ?   A . n 
A 1 14  MET 14  3   ?   ?   ?   A . n 
A 1 15  ALA 15  4   ?   ?   ?   A . n 
A 1 16  LYS 16  5   ?   ?   ?   A . n 
A 1 17  ASP 17  6   ?   ?   ?   A . n 
A 1 18  LYS 18  7   ?   ?   ?   A . n 
A 1 19  GLY 19  8   ?   ?   ?   A . n 
A 1 20  PHE 20  9   ?   ?   ?   A . n 
A 1 21  PHE 21  10  ?   ?   ?   A . n 
A 1 22  LYS 22  11  ?   ?   ?   A . n 
A 1 23  LYS 23  12  ?   ?   ?   A . n 
A 1 24  ALA 24  13  ?   ?   ?   A . n 
A 1 25  LYS 25  14  ?   ?   ?   A . n 
A 1 26  MET 26  15  ?   ?   ?   A . n 
A 1 27  GLU 27  16  ?   ?   ?   A . n 
A 1 28  LYS 28  17  ?   ?   ?   A . n 
A 1 29  ASN 29  18  ?   ?   ?   A . n 
A 1 30  LYS 30  19  ?   ?   ?   A . n 
A 1 31  ARG 31  20  ?   ?   ?   A . n 
A 1 32  LEU 32  21  ?   ?   ?   A . n 
A 1 33  VAL 33  22  ?   ?   ?   A . n 
A 1 34  THR 34  23  ?   ?   ?   A . n 
A 1 35  PRO 35  24  ?   ?   ?   A . n 
A 1 36  TYR 36  25  ?   ?   ?   A . n 
A 1 37  SER 37  26  26  SER SER A . n 
A 1 38  GLU 38  27  27  GLU GLU A . n 
A 1 39  GLU 39  28  28  GLU GLU A . n 
A 1 40  CYS 40  29  29  CYS CYS A . n 
A 1 41  ALA 41  30  30  ALA ALA A . n 
A 1 42  ILE 42  31  31  ILE ILE A . n 
A 1 43  GLN 43  32  32  GLN GLN A . n 
A 1 44  ILE 44  33  33  ILE ILE A . n 
A 1 45  PRO 45  34  34  PRO PRO A . n 
A 1 46  SER 46  35  35  SER SER A . n 
A 1 47  GLU 47  36  36  GLU GLU A . n 
A 1 48  ILE 48  37  37  ILE ILE A . n 
A 1 49  ASP 49  38  38  ASP ASP A . n 
A 1 50  ASN 50  39  39  ASN ASN A . n 
A 1 51  GLU 51  40  40  GLU GLU A . n 
A 1 52  GLN 52  41  41  GLN GLN A . n 
A 1 53  MET 53  42  42  MET MET A . n 
A 1 54  GLN 54  43  43  GLN GLN A . n 
A 1 55  ARG 55  44  44  ARG ARG A . n 
A 1 56  MET 56  45  45  MET MET A . n 
A 1 57  PRO 57  46  46  PRO PRO A . n 
A 1 58  ALA 58  47  47  ALA ALA A . n 
A 1 59  GLY 59  48  48  GLY GLY A . n 
A 1 60  GLY 60  49  49  GLY GLY A . n 
A 1 61  GLU 61  50  50  GLU GLU A . n 
A 1 62  GLU 62  51  51  GLU GLU A . n 
A 1 63  ASP 63  52  52  ASP ASP A . n 
A 1 64  GLN 64  53  53  GLN GLN A . n 
A 1 65  TYR 65  54  54  TYR TYR A . n 
A 1 66  LEU 66  55  55  LEU LEU A . n 
A 1 67  ARG 67  56  56  ARG ARG A . n 
A 1 68  ILE 68  57  57  ILE ILE A . n 
A 1 69  LYS 69  58  58  LYS LYS A . n 
A 1 70  HIS 70  59  59  HIS HIS A . n 
A 1 71  MET 71  60  60  MET MET A . n 
A 1 72  SER 72  61  61  SER SER A . n 
A 1 73  ALA 73  62  62  ALA ALA A . n 
A 1 74  LEU 74  63  63  LEU LEU A . n 
A 1 75  ILE 75  64  64  ILE ILE A . n 
A 1 76  LYS 76  65  65  LYS LYS A . n 
A 1 77  LYS 77  66  66  LYS LYS A . n 
A 1 78  TYR 78  67  67  TYR TYR A . n 
A 1 79  GLY 79  68  68  GLY GLY A . n 
A 1 80  ASP 80  69  69  ASP ASP A . n 
A 1 81  LEU 81  70  70  LEU LEU A . n 
A 1 82  PRO 82  71  71  PRO PRO A . n 
A 1 83  VAL 83  72  72  VAL VAL A . n 
A 1 84  ILE 84  73  73  ILE ILE A . n 
A 1 85  THR 85  74  74  THR THR A . n 
A 1 86  THR 86  75  75  THR THR A . n 
A 1 87  GLN 87  76  76  GLN GLN A . n 
A 1 88  GLU 88  77  77  GLU GLU A . n 
A 1 89  THR 89  78  78  THR THR A . n 
A 1 90  ARG 90  79  79  ARG ARG A . n 
A 1 91  LEU 91  80  80  LEU LEU A . n 
A 1 92  PRO 92  81  81  PRO PRO A . n 
A 1 93  TYR 93  82  82  TYR TYR A . n 
A 1 94  TYR 94  83  83  TYR TYR A . n 
A 1 95  TRP 95  84  84  TRP TRP A . n 
A 1 96  LEU 96  85  85  LEU LEU A . n 
A 1 97  ASP 97  86  86  ASP ASP A . n 
A 1 98  LEU 98  87  87  LEU LEU A . n 
A 1 99  PHE 99  88  88  PHE PHE A . n 
A 1 100 ALA 100 89  89  ALA ALA A . n 
A 1 101 ALA 101 90  90  ALA ALA A . n 
A 1 102 ILE 102 91  91  ILE ILE A . n 
A 1 103 ASP 103 92  92  ASP ASP A . n 
A 1 104 GLU 104 93  93  GLU GLU A . n 
A 1 105 GLY 105 94  94  GLY GLY A . n 
A 1 106 ASP 106 95  95  ASP ASP A . n 
A 1 107 THR 107 96  96  THR THR A . n 
A 1 108 PRO 108 97  97  PRO PRO A . n 
A 1 109 LYS 109 98  98  LYS LYS A . n 
A 1 110 ALA 110 99  99  ALA ALA A . n 
A 1 111 HIS 111 100 100 HIS HIS A . n 
A 1 112 ALA 112 101 101 ALA ALA A . n 
A 1 113 LEU 113 102 102 LEU LEU A . n 
A 1 114 PHE 114 103 103 PHE PHE A . n 
A 1 115 HIS 115 104 104 HIS HIS A . n 
A 1 116 LEU 116 105 105 LEU LEU A . n 
A 1 117 LEU 117 106 106 LEU LEU A . n 
A 1 118 PRO 118 107 107 PRO PRO A . n 
A 1 119 GLN 119 108 108 GLN GLN A . n 
A 1 120 ASP 120 109 109 ASP ASP A . n 
A 1 121 ASP 121 110 110 ASP ASP A . n 
A 1 122 ILE 122 111 111 ILE ILE A . n 
A 1 123 ILE 123 112 112 ILE ILE A . n 
A 1 124 LEU 124 113 113 LEU LEU A . n 
A 1 125 ARG 125 114 114 ARG ARG A . n 
A 1 126 ALA 126 115 115 ALA ALA A . n 
A 1 127 LEU 127 116 116 LEU LEU A . n 
A 1 128 ARG 128 117 117 ARG ARG A . n 
A 1 129 ALA 129 118 118 ALA ALA A . n 
A 1 130 VAL 130 119 119 VAL VAL A . n 
A 1 131 HIS 131 120 120 HIS HIS A . n 
A 1 132 SER 132 121 121 SER SER A . n 
A 1 133 GLU 133 122 122 GLU GLU A . n 
A 1 134 ASP 134 123 123 ASP ASP A . n 
A 1 135 TYR 135 124 124 TYR TYR A . n 
A 1 136 LEU 136 125 125 LEU LEU A . n 
A 1 137 TYR 137 126 126 TYR TYR A . n 
A 1 138 GLN 138 127 127 GLN GLN A . n 
A 1 139 LEU 139 128 128 LEU LEU A . n 
A 1 140 ILE 140 129 129 ILE ILE A . n 
A 1 141 LYS 141 130 130 LYS LYS A . n 
A 1 142 TYR 142 131 131 TYR TYR A . n 
A 1 143 CYS 143 132 132 CYS CYS A . n 
A 1 144 ILE 144 133 133 ILE ILE A . n 
A 1 145 GLN 145 134 134 GLN GLN A . n 
A 1 146 ALA 146 135 135 ALA ALA A . n 
A 1 147 LYS 147 136 136 LYS LYS A . n 
A 1 148 HIS 148 137 137 HIS HIS A . n 
A 1 149 PHE 149 138 138 PHE PHE A . n 
A 1 150 GLY 150 139 139 GLY GLY A . n 
A 1 151 PHE 151 140 140 PHE PHE A . n 
A 1 152 LYS 152 141 141 LYS LYS A . n 
A 1 153 GLN 153 142 142 GLN GLN A . n 
A 1 154 LEU 154 143 143 LEU LEU A . n 
A 1 155 ASN 155 144 144 ASN ASN A . n 
A 1 156 ALA 156 145 145 ALA ALA A . n 
A 1 157 ASP 157 146 146 ASP ASP A . n 
A 1 158 LEU 158 147 147 LEU LEU A . n 
A 1 159 VAL 159 148 148 VAL VAL A . n 
A 1 160 VAL 160 149 149 VAL VAL A . n 
A 1 161 THR 161 150 150 THR THR A . n 
A 1 162 PRO 162 151 151 PRO PRO A . n 
A 1 163 LYS 163 152 152 LYS LYS A . n 
A 1 164 THR 164 153 153 THR THR A . n 
A 1 165 PHE 165 154 154 PHE PHE A . n 
A 1 166 GLU 166 155 155 GLU GLU A . n 
A 1 167 ILE 167 156 156 ILE ILE A . n 
A 1 168 LEU 168 157 157 LEU LEU A . n 
A 1 169 ILE 169 158 158 ILE ILE A . n 
A 1 170 ARG 170 159 159 ARG ARG A . n 
A 1 171 ASP 171 160 160 ASP ASP A . n 
A 1 172 CYS 172 161 161 CYS CYS A . n 
A 1 173 ALA 173 162 162 ALA ALA A . n 
A 1 174 THR 174 163 163 THR THR A . n 
A 1 175 THR 175 164 164 THR THR A . n 
A 1 176 LEU 176 165 165 LEU LEU A . n 
A 1 177 PHE 177 166 166 PHE PHE A . n 
A 1 178 ASN 178 167 167 ASN ASN A . n 
A 1 179 PRO 179 168 168 PRO PRO A . n 
A 1 180 ALA 180 169 169 ALA ALA A . n 
A 1 181 LYS 181 170 170 LYS LYS A . n 
A 1 182 ALA 182 171 171 ALA ALA A . n 
A 1 183 HIS 183 172 172 HIS HIS A . n 
A 1 184 PHE 184 173 173 PHE PHE A . n 
A 1 185 SER 185 174 174 SER SER A . n 
A 1 186 PHE 186 175 175 PHE PHE A . n 
A 1 187 GLY 187 176 176 GLY GLY A . n 
A 1 188 LEU 188 177 177 LEU LEU A . n 
A 1 189 PRO 189 178 178 PRO PRO A . n 
A 1 190 SER 190 179 179 SER SER A . n 
A 1 191 HIS 191 180 180 HIS HIS A . n 
A 1 192 HIS 192 181 181 HIS HIS A . n 
A 1 193 ALA 193 182 182 ALA ALA A . n 
A 1 194 TYR 194 183 183 TYR TYR A . n 
A 1 195 THR 195 184 184 THR THR A . n 
A 1 196 GLN 196 185 185 GLN GLN A . n 
A 1 197 MET 197 186 186 MET MET A . n 
A 1 198 GLY 198 187 187 GLY GLY A . n 
A 1 199 SER 199 188 188 SER SER A . n 
A 1 200 GLY 200 189 189 GLY GLY A . n 
A 1 201 PHE 201 190 190 PHE PHE A . n 
A 1 202 CYS 202 191 191 CYS CYS A . n 
A 1 203 LEU 203 192 192 LEU LEU A . n 
A 1 204 ILE 204 193 193 ILE ILE A . n 
A 1 205 ASN 205 194 194 ASN ASN A . n 
A 1 206 LYS 206 195 195 LYS LYS A . n 
A 1 207 THR 207 196 196 THR THR A . n 
A 1 208 ALA 208 197 197 ALA ALA A . n 
A 1 209 MET 209 198 198 MET MET A . n 
A 1 210 LEU 210 199 199 LEU LEU A . n 
A 1 211 MET 211 200 200 MET MET A . n 
A 1 212 LYS 212 201 201 LYS LYS A . n 
A 1 213 GLN 213 202 202 GLN GLN A . n 
A 1 214 ALA 214 203 203 ALA ALA A . n 
A 1 215 GLU 215 204 204 GLU GLU A . n 
A 1 216 LEU 216 205 205 LEU LEU A . n 
A 1 217 SER 217 206 206 SER SER A . n 
A 1 218 SER 218 207 207 SER SER A . n 
A 1 219 ALA 219 208 208 ALA ALA A . n 
A 1 220 GLN 220 209 209 GLN GLN A . n 
A 1 221 PRO 221 210 210 PRO PRO A . n 
A 1 222 PRO 222 211 211 PRO PRO A . n 
A 1 223 LYS 223 212 212 LYS LYS A . n 
A 1 224 PHE 224 213 213 PHE PHE A . n 
A 1 225 VAL 225 214 214 VAL VAL A . n 
A 1 226 ILE 226 215 215 ILE ILE A . n 
A 1 227 ILE 227 216 216 ILE ILE A . n 
A 1 228 GLY 228 217 217 GLY GLY A . n 
A 1 229 THR 229 218 218 THR THR A . n 
A 1 230 ASP 230 219 219 ASP ASP A . n 
A 1 231 VAL 231 220 220 VAL VAL A . n 
A 1 232 ASN 232 221 221 ASN ASN A . n 
A 1 233 ARG 233 222 222 ARG ARG A . n 
A 1 234 ASP 234 223 223 ASP ASP A . n 
A 1 235 ASN 235 224 224 ASN ASN A . n 
A 1 236 GLY 236 225 225 GLY GLY A . n 
A 1 237 LEU 237 226 226 LEU LEU A . n 
A 1 238 CYS 238 227 227 CYS CYS A . n 
A 1 239 ASP 239 228 228 ASP ASP A . n 
A 1 240 ILE 240 229 229 ILE ILE A . n 
A 1 241 LEU 241 230 230 LEU LEU A . n 
A 1 242 ARG 242 231 231 ARG ARG A . n 
A 1 243 HIS 243 232 232 HIS HIS A . n 
A 1 244 SER 244 233 233 SER SER A . n 
A 1 245 PHE 245 234 234 PHE PHE A . n 
A 1 246 SER 246 235 235 SER SER A . n 
A 1 247 HIS 247 236 236 HIS HIS A . n 
A 1 248 LEU 248 237 237 LEU LEU A . n 
A 1 249 SER 249 238 238 SER SER A . n 
A 1 250 ILE 250 239 239 ILE ILE A . n 
A 1 251 CYS 251 240 240 CYS CYS A . n 
A 1 252 HIS 252 241 241 HIS HIS A . n 
A 1 253 ILE 253 242 242 ILE ILE A . n 
A 1 254 ASP 254 243 243 ASP ASP A . n 
A 1 255 VAL 255 244 244 VAL VAL A . n 
A 1 256 PHE 256 245 245 PHE PHE A . n 
A 1 257 ASP 257 246 246 ASP ASP A . n 
A 1 258 SER 258 247 247 SER SER A . n 
A 1 259 ARG 259 248 248 ARG ARG A . n 
A 1 260 VAL 260 249 249 VAL VAL A . n 
A 1 261 TYR 261 250 250 TYR TYR A . n 
A 1 262 PRO 262 251 251 PRO PRO A . n 
A 1 263 GLN 263 252 252 GLN GLN A . n 
A 1 264 GLN 264 253 253 GLN GLN A . n 
A 1 265 ASP 265 254 254 ASP ASP A . n 
A 1 266 PHE 266 255 255 PHE PHE A . n 
A 1 267 ALA 267 256 256 ALA ALA A . n 
A 1 268 TYR 268 257 257 TYR TYR A . n 
A 1 269 ILE 269 258 258 ILE ILE A . n 
A 1 270 ASN 270 259 259 ASN ASN A . n 
A 1 271 ASN 271 260 260 ASN ASN A . n 
A 1 272 GLU 272 261 261 GLU GLU A . n 
A 1 273 PHE 273 262 262 PHE PHE A . n 
A 1 274 ASN 274 263 263 ASN ASN A . n 
A 1 275 SER 275 264 264 SER SER A . n 
A 1 276 GLU 276 265 265 GLU GLU A . n 
A 1 277 GLY 277 266 266 GLY GLY A . n 
A 1 278 VAL 278 267 267 VAL VAL A . n 
A 1 279 ASP 279 268 268 ASP ASP A . n 
A 1 280 ILE 280 269 269 ILE ILE A . n 
A 1 281 GLY 281 270 270 GLY GLY A . n 
A 1 282 LYS 282 271 271 LYS LYS A . n 
A 1 283 ASN 283 272 272 ASN ASN A . n 
A 1 284 ILE 284 273 273 ILE ILE A . n 
A 1 285 HIS 285 274 274 HIS HIS A . n 
A 1 286 VAL 286 275 275 VAL VAL A . n 
A 1 287 TRP 287 276 276 TRP TRP A . n 
A 1 288 HIS 288 277 277 HIS HIS A . n 
A 1 289 HIS 289 278 278 HIS HIS A . n 
A 1 290 ASN 290 279 279 ASN ASN A . n 
A 1 291 ASN 291 280 280 ASN ASN A . n 
A 1 292 LEU 292 281 281 LEU LEU A . n 
A 1 293 ASN 293 282 282 ASN ASN A . n 
A 1 294 TYR 294 283 283 TYR TYR A . n 
A 1 295 TYR 295 284 284 TYR TYR A . n 
A 1 296 ALA 296 285 285 ALA ALA A . n 
A 1 297 VAL 297 286 286 VAL VAL A . n 
A 1 298 ASP 298 287 287 ASP ASP A . n 
A 1 299 LEU 299 288 288 LEU LEU A . n 
A 1 300 SER 300 289 289 SER SER A . n 
A 1 301 LEU 301 290 290 LEU LEU A . n 
A 1 302 THR 302 291 291 THR THR A . n 
A 1 303 SER 303 292 292 SER SER A . n 
A 1 304 ARG 304 293 293 ARG ARG A . n 
A 1 305 LYS 305 294 294 LYS LYS A . n 
A 1 306 SER 306 295 295 SER SER A . n 
A 1 307 VAL 307 296 296 VAL VAL A . n 
A 1 308 GLY 308 297 297 GLY GLY A . n 
A 1 309 VAL 309 298 298 VAL VAL A . n 
A 1 310 HIS 310 299 299 HIS HIS A . n 
A 1 311 PRO 311 300 300 PRO PRO A . n 
A 1 312 ALA 312 301 301 ALA ALA A . n 
A 1 313 LEU 313 302 302 LEU LEU A . n 
A 1 314 LEU 314 303 303 LEU LEU A . n 
A 1 315 PHE 315 304 304 PHE PHE A . n 
A 1 316 ALA 316 305 305 ALA ALA A . n 
A 1 317 LEU 317 306 306 LEU LEU A . n 
A 1 318 GLU 318 307 307 GLU GLU A . n 
A 1 319 GLN 319 308 308 GLN GLN A . n 
A 1 320 LEU 320 309 309 LEU LEU A . n 
A 1 321 LYS 321 310 310 LYS LYS A . n 
A 1 322 GLU 322 311 311 GLU GLU A . n 
A 1 323 SER 323 312 312 SER SER A . n 
A 1 324 ILE 324 313 313 ILE ILE A . n 
A 1 325 ARG 325 314 314 ARG ARG A . n 
A 1 326 GLU 326 315 315 GLU GLU A . n 
A 1 327 ALA 327 316 316 ALA ALA A . n 
A 1 328 LYS 328 317 317 LYS LYS A . n 
A 1 329 ALA 329 318 318 ALA ALA A . n 
A 1 330 LYS 330 319 319 LYS LYS A . n 
A 1 331 GLY 331 320 320 GLY GLY A . n 
A 1 332 GLN 332 321 321 GLN GLN A . n 
A 1 333 LYS 333 322 322 LYS LYS A . n 
A 1 334 ILE 334 323 323 ILE ILE A . n 
A 1 335 ALA 335 324 324 ALA ALA A . n 
A 1 336 LEU 336 325 325 LEU LEU A . n 
A 1 337 TYR 337 326 326 TYR TYR A . n 
A 1 338 LEU 338 327 327 LEU LEU A . n 
A 1 339 PRO 339 328 328 PRO PRO A . n 
A 1 340 THR 340 329 329 THR THR A . n 
A 1 341 GLY 341 330 330 GLY GLY A . n 
A 1 342 TRP 342 331 331 TRP TRP A . n 
A 1 343 ASP 343 332 332 ASP ASP A . n 
A 1 344 SER 344 333 333 SER SER A . n 
A 1 345 HIS 345 334 334 HIS HIS A . n 
A 1 346 GLU 346 335 335 GLU GLU A . n 
A 1 347 ASP 347 336 336 ASP ASP A . n 
A 1 348 GLU 348 337 337 GLU GLU A . n 
A 1 349 THR 349 338 338 THR THR A . n 
A 1 350 ALA 350 339 339 ALA ALA A . n 
A 1 351 TYR 351 340 340 TYR TYR A . n 
A 1 352 CYS 352 341 341 CYS CYS A . n 
A 1 353 GLY 353 342 342 GLY GLY A . n 
A 1 354 LYS 354 343 343 LYS LYS A . n 
A 1 355 PHE 355 344 344 PHE PHE A . n 
A 1 356 VAL 356 345 345 VAL VAL A . n 
A 1 357 ASN 357 346 346 ASN ASN A . n 
A 1 358 GLY 358 347 347 GLY GLY A . n 
A 1 359 ARG 359 348 348 ARG ARG A . n 
A 1 360 MET 360 349 349 MET MET A . n 
A 1 361 MET 361 350 350 MET MET A . n 
A 1 362 GLY 362 351 351 GLY GLY A . n 
A 1 363 LYS 363 352 352 LYS LYS A . n 
A 1 364 THR 364 353 353 THR THR A . n 
A 1 365 ALA 365 354 354 ALA ALA A . n 
A 1 366 ALA 366 355 355 ALA ALA A . n 
A 1 367 HIS 367 356 356 HIS HIS A . n 
A 1 368 GLN 368 357 357 GLN GLN A . n 
A 1 369 PHE 369 358 358 PHE PHE A . n 
A 1 370 ARG 370 359 359 ARG ARG A . n 
A 1 371 PHE 371 360 360 PHE PHE A . n 
A 1 372 ASN 372 361 361 ASN ASN A . n 
A 1 373 ASP 373 362 362 ASP ASP A . n 
A 1 374 GLY 374 363 363 GLY GLY A . n 
A 1 375 ASP 375 364 364 ASP ASP A . n 
A 1 376 LEU 376 365 365 LEU LEU A . n 
A 1 377 GLY 377 366 366 GLY GLY A . n 
A 1 378 TYR 378 367 367 TYR TYR A . n 
A 1 379 PHE 379 368 368 PHE PHE A . n 
A 1 380 TYR 380 369 369 TYR TYR A . n 
A 1 381 GLU 381 370 370 GLU GLU A . n 
A 1 382 SER 382 371 371 SER SER A . n 
A 1 383 ILE 383 372 372 ILE ILE A . n 
A 1 384 PHE 384 373 373 PHE PHE A . n 
A 1 385 THR 385 374 374 THR THR A . n 
A 1 386 LEU 386 375 375 LEU LEU A . n 
A 1 387 TYR 387 376 376 TYR TYR A . n 
A 1 388 ASN 388 377 377 ASN ASN A . n 
A 1 389 GLU 389 378 378 GLU GLU A . n 
A 1 390 ASN 390 379 379 ASN ASN A . n 
A 1 391 LYS 391 380 380 LYS LYS A . n 
A 1 392 ASP 392 381 381 ASP ASP A . n 
A 1 393 CYS 393 382 382 CYS CYS A . n 
A 1 394 VAL 394 383 383 VAL VAL A . n 
A 1 395 ASP 395 384 384 ASP ASP A . n 
A 1 396 THR 396 385 385 THR THR A . n 
A 1 397 ILE 397 386 386 ILE ILE A . n 
A 1 398 TYR 398 387 387 TYR TYR A . n 
A 1 399 TRP 399 388 388 TRP TRP A . n 
A 1 400 GLY 400 389 389 GLY GLY A . n 
A 1 401 LEU 401 390 390 LEU LEU A . n 
A 1 402 GLU 402 391 391 GLU GLU A . n 
A 1 403 GLY 403 392 392 GLY GLY A . n 
A 1 404 GLY 404 393 393 GLY GLY A . n 
A 1 405 TYR 405 394 394 TYR TYR A . n 
A 1 406 ASP 406 395 395 ASP ASP A . n 
A 1 407 ARG 407 396 396 ARG ARG A . n 
A 1 408 THR 408 397 397 THR THR A . n 
A 1 409 MET 409 398 398 MET MET A . n 
A 1 410 TYR 410 399 399 TYR TYR A . n 
A 1 411 GLU 411 400 400 GLU GLU A . n 
A 1 412 ARG 412 401 401 ARG ARG A . n 
A 1 413 GLU 413 402 402 GLU GLU A . n 
A 1 414 LEU 414 403 403 LEU LEU A . n 
A 1 415 LYS 415 404 404 LYS LYS A . n 
A 1 416 ILE 416 405 405 ILE ILE A . n 
A 1 417 LEU 417 406 406 LEU LEU A . n 
A 1 418 LEU 418 407 407 LEU LEU A . n 
A 1 419 GLN 419 408 408 GLN GLN A . n 
A 1 420 VAL 420 409 409 VAL VAL A . n 
A 1 421 ILE 421 410 410 ILE ILE A . n 
A 1 422 GLU 422 411 411 GLU GLU A . n 
A 1 423 LYS 423 412 412 LYS LYS A . n 
A 1 424 GLN 424 413 413 GLN GLN A . n 
A 1 425 LEU 425 414 414 LEU LEU A . n 
A 1 426 LEU 426 415 415 LEU LEU A . n 
A 1 427 PRO 427 416 416 PRO PRO A . n 
A 1 428 LYS 428 417 417 LYS LYS A . n 
A 1 429 ASP 429 418 418 ASP ASP A . n 
A 1 430 SER 430 419 ?   ?   ?   A . n 
A 1 431 ASN 431 420 ?   ?   ?   A . n 
A 1 432 SER 432 421 ?   ?   ?   A . n 
A 1 433 HIS 433 422 ?   ?   ?   A . n 
A 1 434 SER 434 423 ?   ?   ?   A . n 
A 1 435 MET 435 424 ?   ?   ?   A . n 
A 1 436 SER 436 425 ?   ?   ?   A . n 
A 1 437 TYR 437 426 ?   ?   ?   A . n 
B 1 1   MET 1   -10 ?   ?   ?   B . n 
B 1 2   ALA 2   -9  ?   ?   ?   B . n 
B 1 3   HIS 3   -8  ?   ?   ?   B . n 
B 1 4   HIS 4   -7  ?   ?   ?   B . n 
B 1 5   HIS 5   -6  ?   ?   ?   B . n 
B 1 6   HIS 6   -5  ?   ?   ?   B . n 
B 1 7   HIS 7   -4  ?   ?   ?   B . n 
B 1 8   HIS 8   -3  ?   ?   ?   B . n 
B 1 9   VAL 9   -2  ?   ?   ?   B . n 
B 1 10  GLY 10  -1  ?   ?   ?   B . n 
B 1 11  THR 11  0   ?   ?   ?   B . n 
B 1 12  MET 12  1   ?   ?   ?   B . n 
B 1 13  ASP 13  2   ?   ?   ?   B . n 
B 1 14  MET 14  3   ?   ?   ?   B . n 
B 1 15  ALA 15  4   ?   ?   ?   B . n 
B 1 16  LYS 16  5   ?   ?   ?   B . n 
B 1 17  ASP 17  6   ?   ?   ?   B . n 
B 1 18  LYS 18  7   ?   ?   ?   B . n 
B 1 19  GLY 19  8   ?   ?   ?   B . n 
B 1 20  PHE 20  9   ?   ?   ?   B . n 
B 1 21  PHE 21  10  ?   ?   ?   B . n 
B 1 22  LYS 22  11  ?   ?   ?   B . n 
B 1 23  LYS 23  12  ?   ?   ?   B . n 
B 1 24  ALA 24  13  ?   ?   ?   B . n 
B 1 25  LYS 25  14  ?   ?   ?   B . n 
B 1 26  MET 26  15  ?   ?   ?   B . n 
B 1 27  GLU 27  16  ?   ?   ?   B . n 
B 1 28  LYS 28  17  ?   ?   ?   B . n 
B 1 29  ASN 29  18  ?   ?   ?   B . n 
B 1 30  LYS 30  19  ?   ?   ?   B . n 
B 1 31  ARG 31  20  ?   ?   ?   B . n 
B 1 32  LEU 32  21  ?   ?   ?   B . n 
B 1 33  VAL 33  22  ?   ?   ?   B . n 
B 1 34  THR 34  23  ?   ?   ?   B . n 
B 1 35  PRO 35  24  ?   ?   ?   B . n 
B 1 36  TYR 36  25  ?   ?   ?   B . n 
B 1 37  SER 37  26  ?   ?   ?   B . n 
B 1 38  GLU 38  27  27  GLU GLU B . n 
B 1 39  GLU 39  28  28  GLU GLU B . n 
B 1 40  CYS 40  29  29  CYS CYS B . n 
B 1 41  ALA 41  30  30  ALA ALA B . n 
B 1 42  ILE 42  31  31  ILE ILE B . n 
B 1 43  GLN 43  32  32  GLN GLN B . n 
B 1 44  ILE 44  33  33  ILE ILE B . n 
B 1 45  PRO 45  34  34  PRO PRO B . n 
B 1 46  SER 46  35  35  SER SER B . n 
B 1 47  GLU 47  36  36  GLU GLU B . n 
B 1 48  ILE 48  37  37  ILE ILE B . n 
B 1 49  ASP 49  38  38  ASP ASP B . n 
B 1 50  ASN 50  39  39  ASN ASN B . n 
B 1 51  GLU 51  40  40  GLU GLU B . n 
B 1 52  GLN 52  41  41  GLN GLN B . n 
B 1 53  MET 53  42  42  MET MET B . n 
B 1 54  GLN 54  43  43  GLN GLN B . n 
B 1 55  ARG 55  44  44  ARG ARG B . n 
B 1 56  MET 56  45  45  MET MET B . n 
B 1 57  PRO 57  46  46  PRO PRO B . n 
B 1 58  ALA 58  47  47  ALA ALA B . n 
B 1 59  GLY 59  48  48  GLY GLY B . n 
B 1 60  GLY 60  49  49  GLY GLY B . n 
B 1 61  GLU 61  50  50  GLU GLU B . n 
B 1 62  GLU 62  51  51  GLU GLU B . n 
B 1 63  ASP 63  52  52  ASP ASP B . n 
B 1 64  GLN 64  53  53  GLN GLN B . n 
B 1 65  TYR 65  54  54  TYR TYR B . n 
B 1 66  LEU 66  55  55  LEU LEU B . n 
B 1 67  ARG 67  56  56  ARG ARG B . n 
B 1 68  ILE 68  57  57  ILE ILE B . n 
B 1 69  LYS 69  58  58  LYS LYS B . n 
B 1 70  HIS 70  59  59  HIS HIS B . n 
B 1 71  MET 71  60  60  MET MET B . n 
B 1 72  SER 72  61  61  SER SER B . n 
B 1 73  ALA 73  62  62  ALA ALA B . n 
B 1 74  LEU 74  63  63  LEU LEU B . n 
B 1 75  ILE 75  64  64  ILE ILE B . n 
B 1 76  LYS 76  65  65  LYS LYS B . n 
B 1 77  LYS 77  66  66  LYS LYS B . n 
B 1 78  TYR 78  67  67  TYR TYR B . n 
B 1 79  GLY 79  68  68  GLY GLY B . n 
B 1 80  ASP 80  69  69  ASP ASP B . n 
B 1 81  LEU 81  70  70  LEU LEU B . n 
B 1 82  PRO 82  71  71  PRO PRO B . n 
B 1 83  VAL 83  72  72  VAL VAL B . n 
B 1 84  ILE 84  73  73  ILE ILE B . n 
B 1 85  THR 85  74  74  THR THR B . n 
B 1 86  THR 86  75  75  THR THR B . n 
B 1 87  GLN 87  76  76  GLN GLN B . n 
B 1 88  GLU 88  77  77  GLU GLU B . n 
B 1 89  THR 89  78  78  THR THR B . n 
B 1 90  ARG 90  79  79  ARG ARG B . n 
B 1 91  LEU 91  80  80  LEU LEU B . n 
B 1 92  PRO 92  81  81  PRO PRO B . n 
B 1 93  TYR 93  82  82  TYR TYR B . n 
B 1 94  TYR 94  83  83  TYR TYR B . n 
B 1 95  TRP 95  84  84  TRP TRP B . n 
B 1 96  LEU 96  85  85  LEU LEU B . n 
B 1 97  ASP 97  86  86  ASP ASP B . n 
B 1 98  LEU 98  87  87  LEU LEU B . n 
B 1 99  PHE 99  88  88  PHE PHE B . n 
B 1 100 ALA 100 89  89  ALA ALA B . n 
B 1 101 ALA 101 90  90  ALA ALA B . n 
B 1 102 ILE 102 91  91  ILE ILE B . n 
B 1 103 ASP 103 92  92  ASP ASP B . n 
B 1 104 GLU 104 93  93  GLU GLU B . n 
B 1 105 GLY 105 94  94  GLY GLY B . n 
B 1 106 ASP 106 95  95  ASP ASP B . n 
B 1 107 THR 107 96  96  THR THR B . n 
B 1 108 PRO 108 97  97  PRO PRO B . n 
B 1 109 LYS 109 98  98  LYS LYS B . n 
B 1 110 ALA 110 99  99  ALA ALA B . n 
B 1 111 HIS 111 100 100 HIS HIS B . n 
B 1 112 ALA 112 101 101 ALA ALA B . n 
B 1 113 LEU 113 102 102 LEU LEU B . n 
B 1 114 PHE 114 103 103 PHE PHE B . n 
B 1 115 HIS 115 104 104 HIS HIS B . n 
B 1 116 LEU 116 105 105 LEU LEU B . n 
B 1 117 LEU 117 106 106 LEU LEU B . n 
B 1 118 PRO 118 107 107 PRO PRO B . n 
B 1 119 GLN 119 108 108 GLN GLN B . n 
B 1 120 ASP 120 109 109 ASP ASP B . n 
B 1 121 ASP 121 110 110 ASP ASP B . n 
B 1 122 ILE 122 111 111 ILE ILE B . n 
B 1 123 ILE 123 112 112 ILE ILE B . n 
B 1 124 LEU 124 113 113 LEU LEU B . n 
B 1 125 ARG 125 114 114 ARG ARG B . n 
B 1 126 ALA 126 115 115 ALA ALA B . n 
B 1 127 LEU 127 116 116 LEU LEU B . n 
B 1 128 ARG 128 117 117 ARG ARG B . n 
B 1 129 ALA 129 118 118 ALA ALA B . n 
B 1 130 VAL 130 119 119 VAL VAL B . n 
B 1 131 HIS 131 120 120 HIS HIS B . n 
B 1 132 SER 132 121 121 SER SER B . n 
B 1 133 GLU 133 122 122 GLU GLU B . n 
B 1 134 ASP 134 123 123 ASP ASP B . n 
B 1 135 TYR 135 124 124 TYR TYR B . n 
B 1 136 LEU 136 125 125 LEU LEU B . n 
B 1 137 TYR 137 126 126 TYR TYR B . n 
B 1 138 GLN 138 127 127 GLN GLN B . n 
B 1 139 LEU 139 128 128 LEU LEU B . n 
B 1 140 ILE 140 129 129 ILE ILE B . n 
B 1 141 LYS 141 130 130 LYS LYS B . n 
B 1 142 TYR 142 131 131 TYR TYR B . n 
B 1 143 CYS 143 132 132 CYS CYS B . n 
B 1 144 ILE 144 133 133 ILE ILE B . n 
B 1 145 GLN 145 134 134 GLN GLN B . n 
B 1 146 ALA 146 135 135 ALA ALA B . n 
B 1 147 LYS 147 136 136 LYS LYS B . n 
B 1 148 HIS 148 137 137 HIS HIS B . n 
B 1 149 PHE 149 138 138 PHE PHE B . n 
B 1 150 GLY 150 139 139 GLY GLY B . n 
B 1 151 PHE 151 140 140 PHE PHE B . n 
B 1 152 LYS 152 141 141 LYS LYS B . n 
B 1 153 GLN 153 142 142 GLN GLN B . n 
B 1 154 LEU 154 143 143 LEU LEU B . n 
B 1 155 ASN 155 144 144 ASN ASN B . n 
B 1 156 ALA 156 145 145 ALA ALA B . n 
B 1 157 ASP 157 146 146 ASP ASP B . n 
B 1 158 LEU 158 147 147 LEU LEU B . n 
B 1 159 VAL 159 148 148 VAL VAL B . n 
B 1 160 VAL 160 149 149 VAL VAL B . n 
B 1 161 THR 161 150 150 THR THR B . n 
B 1 162 PRO 162 151 151 PRO PRO B . n 
B 1 163 LYS 163 152 152 LYS LYS B . n 
B 1 164 THR 164 153 153 THR THR B . n 
B 1 165 PHE 165 154 154 PHE PHE B . n 
B 1 166 GLU 166 155 155 GLU GLU B . n 
B 1 167 ILE 167 156 156 ILE ILE B . n 
B 1 168 LEU 168 157 157 LEU LEU B . n 
B 1 169 ILE 169 158 158 ILE ILE B . n 
B 1 170 ARG 170 159 159 ARG ARG B . n 
B 1 171 ASP 171 160 160 ASP ASP B . n 
B 1 172 CYS 172 161 161 CYS CYS B . n 
B 1 173 ALA 173 162 162 ALA ALA B . n 
B 1 174 THR 174 163 163 THR THR B . n 
B 1 175 THR 175 164 164 THR THR B . n 
B 1 176 LEU 176 165 165 LEU LEU B . n 
B 1 177 PHE 177 166 166 PHE PHE B . n 
B 1 178 ASN 178 167 167 ASN ASN B . n 
B 1 179 PRO 179 168 168 PRO PRO B . n 
B 1 180 ALA 180 169 169 ALA ALA B . n 
B 1 181 LYS 181 170 170 LYS LYS B . n 
B 1 182 ALA 182 171 171 ALA ALA B . n 
B 1 183 HIS 183 172 172 HIS HIS B . n 
B 1 184 PHE 184 173 173 PHE PHE B . n 
B 1 185 SER 185 174 174 SER SER B . n 
B 1 186 PHE 186 175 175 PHE PHE B . n 
B 1 187 GLY 187 176 176 GLY GLY B . n 
B 1 188 LEU 188 177 177 LEU LEU B . n 
B 1 189 PRO 189 178 178 PRO PRO B . n 
B 1 190 SER 190 179 179 SER SER B . n 
B 1 191 HIS 191 180 180 HIS HIS B . n 
B 1 192 HIS 192 181 181 HIS HIS B . n 
B 1 193 ALA 193 182 182 ALA ALA B . n 
B 1 194 TYR 194 183 183 TYR TYR B . n 
B 1 195 THR 195 184 184 THR THR B . n 
B 1 196 GLN 196 185 185 GLN GLN B . n 
B 1 197 MET 197 186 186 MET MET B . n 
B 1 198 GLY 198 187 187 GLY GLY B . n 
B 1 199 SER 199 188 188 SER SER B . n 
B 1 200 GLY 200 189 189 GLY GLY B . n 
B 1 201 PHE 201 190 190 PHE PHE B . n 
B 1 202 CYS 202 191 191 CYS CYS B . n 
B 1 203 LEU 203 192 192 LEU LEU B . n 
B 1 204 ILE 204 193 193 ILE ILE B . n 
B 1 205 ASN 205 194 194 ASN ASN B . n 
B 1 206 LYS 206 195 195 LYS LYS B . n 
B 1 207 THR 207 196 196 THR THR B . n 
B 1 208 ALA 208 197 197 ALA ALA B . n 
B 1 209 MET 209 198 198 MET MET B . n 
B 1 210 LEU 210 199 199 LEU LEU B . n 
B 1 211 MET 211 200 200 MET MET B . n 
B 1 212 LYS 212 201 201 LYS LYS B . n 
B 1 213 GLN 213 202 202 GLN GLN B . n 
B 1 214 ALA 214 203 203 ALA ALA B . n 
B 1 215 GLU 215 204 204 GLU GLU B . n 
B 1 216 LEU 216 205 205 LEU LEU B . n 
B 1 217 SER 217 206 206 SER SER B . n 
B 1 218 SER 218 207 207 SER SER B . n 
B 1 219 ALA 219 208 208 ALA ALA B . n 
B 1 220 GLN 220 209 209 GLN GLN B . n 
B 1 221 PRO 221 210 210 PRO PRO B . n 
B 1 222 PRO 222 211 211 PRO PRO B . n 
B 1 223 LYS 223 212 212 LYS LYS B . n 
B 1 224 PHE 224 213 213 PHE PHE B . n 
B 1 225 VAL 225 214 214 VAL VAL B . n 
B 1 226 ILE 226 215 215 ILE ILE B . n 
B 1 227 ILE 227 216 216 ILE ILE B . n 
B 1 228 GLY 228 217 217 GLY GLY B . n 
B 1 229 THR 229 218 218 THR THR B . n 
B 1 230 ASP 230 219 219 ASP ASP B . n 
B 1 231 VAL 231 220 220 VAL VAL B . n 
B 1 232 ASN 232 221 221 ASN ASN B . n 
B 1 233 ARG 233 222 222 ARG ARG B . n 
B 1 234 ASP 234 223 223 ASP ASP B . n 
B 1 235 ASN 235 224 224 ASN ASN B . n 
B 1 236 GLY 236 225 225 GLY GLY B . n 
B 1 237 LEU 237 226 226 LEU LEU B . n 
B 1 238 CYS 238 227 227 CYS CYS B . n 
B 1 239 ASP 239 228 228 ASP ASP B . n 
B 1 240 ILE 240 229 229 ILE ILE B . n 
B 1 241 LEU 241 230 230 LEU LEU B . n 
B 1 242 ARG 242 231 231 ARG ARG B . n 
B 1 243 HIS 243 232 232 HIS HIS B . n 
B 1 244 SER 244 233 233 SER SER B . n 
B 1 245 PHE 245 234 234 PHE PHE B . n 
B 1 246 SER 246 235 235 SER SER B . n 
B 1 247 HIS 247 236 236 HIS HIS B . n 
B 1 248 LEU 248 237 237 LEU LEU B . n 
B 1 249 SER 249 238 238 SER SER B . n 
B 1 250 ILE 250 239 239 ILE ILE B . n 
B 1 251 CYS 251 240 240 CYS CYS B . n 
B 1 252 HIS 252 241 241 HIS HIS B . n 
B 1 253 ILE 253 242 242 ILE ILE B . n 
B 1 254 ASP 254 243 243 ASP ASP B . n 
B 1 255 VAL 255 244 244 VAL VAL B . n 
B 1 256 PHE 256 245 245 PHE PHE B . n 
B 1 257 ASP 257 246 246 ASP ASP B . n 
B 1 258 SER 258 247 247 SER SER B . n 
B 1 259 ARG 259 248 248 ARG ARG B . n 
B 1 260 VAL 260 249 249 VAL VAL B . n 
B 1 261 TYR 261 250 250 TYR TYR B . n 
B 1 262 PRO 262 251 251 PRO PRO B . n 
B 1 263 GLN 263 252 252 GLN GLN B . n 
B 1 264 GLN 264 253 253 GLN GLN B . n 
B 1 265 ASP 265 254 254 ASP ASP B . n 
B 1 266 PHE 266 255 255 PHE PHE B . n 
B 1 267 ALA 267 256 256 ALA ALA B . n 
B 1 268 TYR 268 257 257 TYR TYR B . n 
B 1 269 ILE 269 258 258 ILE ILE B . n 
B 1 270 ASN 270 259 259 ASN ASN B . n 
B 1 271 ASN 271 260 260 ASN ASN B . n 
B 1 272 GLU 272 261 261 GLU GLU B . n 
B 1 273 PHE 273 262 262 PHE PHE B . n 
B 1 274 ASN 274 263 263 ASN ASN B . n 
B 1 275 SER 275 264 264 SER SER B . n 
B 1 276 GLU 276 265 265 GLU GLU B . n 
B 1 277 GLY 277 266 266 GLY GLY B . n 
B 1 278 VAL 278 267 267 VAL VAL B . n 
B 1 279 ASP 279 268 268 ASP ASP B . n 
B 1 280 ILE 280 269 269 ILE ILE B . n 
B 1 281 GLY 281 270 270 GLY GLY B . n 
B 1 282 LYS 282 271 271 LYS LYS B . n 
B 1 283 ASN 283 272 272 ASN ASN B . n 
B 1 284 ILE 284 273 273 ILE ILE B . n 
B 1 285 HIS 285 274 274 HIS HIS B . n 
B 1 286 VAL 286 275 275 VAL VAL B . n 
B 1 287 TRP 287 276 276 TRP TRP B . n 
B 1 288 HIS 288 277 277 HIS HIS B . n 
B 1 289 HIS 289 278 278 HIS HIS B . n 
B 1 290 ASN 290 279 279 ASN ASN B . n 
B 1 291 ASN 291 280 280 ASN ASN B . n 
B 1 292 LEU 292 281 281 LEU LEU B . n 
B 1 293 ASN 293 282 282 ASN ASN B . n 
B 1 294 TYR 294 283 283 TYR TYR B . n 
B 1 295 TYR 295 284 284 TYR TYR B . n 
B 1 296 ALA 296 285 285 ALA ALA B . n 
B 1 297 VAL 297 286 286 VAL VAL B . n 
B 1 298 ASP 298 287 287 ASP ASP B . n 
B 1 299 LEU 299 288 288 LEU LEU B . n 
B 1 300 SER 300 289 289 SER SER B . n 
B 1 301 LEU 301 290 290 LEU LEU B . n 
B 1 302 THR 302 291 291 THR THR B . n 
B 1 303 SER 303 292 292 SER SER B . n 
B 1 304 ARG 304 293 293 ARG ARG B . n 
B 1 305 LYS 305 294 294 LYS LYS B . n 
B 1 306 SER 306 295 295 SER SER B . n 
B 1 307 VAL 307 296 296 VAL VAL B . n 
B 1 308 GLY 308 297 297 GLY GLY B . n 
B 1 309 VAL 309 298 298 VAL VAL B . n 
B 1 310 HIS 310 299 299 HIS HIS B . n 
B 1 311 PRO 311 300 300 PRO PRO B . n 
B 1 312 ALA 312 301 301 ALA ALA B . n 
B 1 313 LEU 313 302 302 LEU LEU B . n 
B 1 314 LEU 314 303 303 LEU LEU B . n 
B 1 315 PHE 315 304 304 PHE PHE B . n 
B 1 316 ALA 316 305 305 ALA ALA B . n 
B 1 317 LEU 317 306 306 LEU LEU B . n 
B 1 318 GLU 318 307 307 GLU GLU B . n 
B 1 319 GLN 319 308 308 GLN GLN B . n 
B 1 320 LEU 320 309 309 LEU LEU B . n 
B 1 321 LYS 321 310 310 LYS LYS B . n 
B 1 322 GLU 322 311 311 GLU GLU B . n 
B 1 323 SER 323 312 312 SER SER B . n 
B 1 324 ILE 324 313 313 ILE ILE B . n 
B 1 325 ARG 325 314 314 ARG ARG B . n 
B 1 326 GLU 326 315 315 GLU GLU B . n 
B 1 327 ALA 327 316 316 ALA ALA B . n 
B 1 328 LYS 328 317 317 LYS LYS B . n 
B 1 329 ALA 329 318 318 ALA ALA B . n 
B 1 330 LYS 330 319 319 LYS LYS B . n 
B 1 331 GLY 331 320 320 GLY GLY B . n 
B 1 332 GLN 332 321 321 GLN GLN B . n 
B 1 333 LYS 333 322 322 LYS LYS B . n 
B 1 334 ILE 334 323 323 ILE ILE B . n 
B 1 335 ALA 335 324 324 ALA ALA B . n 
B 1 336 LEU 336 325 325 LEU LEU B . n 
B 1 337 TYR 337 326 326 TYR TYR B . n 
B 1 338 LEU 338 327 327 LEU LEU B . n 
B 1 339 PRO 339 328 328 PRO PRO B . n 
B 1 340 THR 340 329 329 THR THR B . n 
B 1 341 GLY 341 330 330 GLY GLY B . n 
B 1 342 TRP 342 331 331 TRP TRP B . n 
B 1 343 ASP 343 332 332 ASP ASP B . n 
B 1 344 SER 344 333 333 SER SER B . n 
B 1 345 HIS 345 334 334 HIS HIS B . n 
B 1 346 GLU 346 335 335 GLU GLU B . n 
B 1 347 ASP 347 336 336 ASP ASP B . n 
B 1 348 GLU 348 337 337 GLU GLU B . n 
B 1 349 THR 349 338 338 THR THR B . n 
B 1 350 ALA 350 339 339 ALA ALA B . n 
B 1 351 TYR 351 340 340 TYR TYR B . n 
B 1 352 CYS 352 341 341 CYS CYS B . n 
B 1 353 GLY 353 342 342 GLY GLY B . n 
B 1 354 LYS 354 343 343 LYS LYS B . n 
B 1 355 PHE 355 344 344 PHE PHE B . n 
B 1 356 VAL 356 345 345 VAL VAL B . n 
B 1 357 ASN 357 346 346 ASN ASN B . n 
B 1 358 GLY 358 347 347 GLY GLY B . n 
B 1 359 ARG 359 348 348 ARG ARG B . n 
B 1 360 MET 360 349 349 MET MET B . n 
B 1 361 MET 361 350 350 MET MET B . n 
B 1 362 GLY 362 351 351 GLY GLY B . n 
B 1 363 LYS 363 352 352 LYS LYS B . n 
B 1 364 THR 364 353 353 THR THR B . n 
B 1 365 ALA 365 354 354 ALA ALA B . n 
B 1 366 ALA 366 355 355 ALA ALA B . n 
B 1 367 HIS 367 356 356 HIS HIS B . n 
B 1 368 GLN 368 357 357 GLN GLN B . n 
B 1 369 PHE 369 358 358 PHE PHE B . n 
B 1 370 ARG 370 359 359 ARG ARG B . n 
B 1 371 PHE 371 360 360 PHE PHE B . n 
B 1 372 ASN 372 361 361 ASN ASN B . n 
B 1 373 ASP 373 362 362 ASP ASP B . n 
B 1 374 GLY 374 363 363 GLY GLY B . n 
B 1 375 ASP 375 364 364 ASP ASP B . n 
B 1 376 LEU 376 365 365 LEU LEU B . n 
B 1 377 GLY 377 366 366 GLY GLY B . n 
B 1 378 TYR 378 367 367 TYR TYR B . n 
B 1 379 PHE 379 368 368 PHE PHE B . n 
B 1 380 TYR 380 369 369 TYR TYR B . n 
B 1 381 GLU 381 370 370 GLU GLU B . n 
B 1 382 SER 382 371 371 SER SER B . n 
B 1 383 ILE 383 372 372 ILE ILE B . n 
B 1 384 PHE 384 373 373 PHE PHE B . n 
B 1 385 THR 385 374 374 THR THR B . n 
B 1 386 LEU 386 375 375 LEU LEU B . n 
B 1 387 TYR 387 376 376 TYR TYR B . n 
B 1 388 ASN 388 377 377 ASN ASN B . n 
B 1 389 GLU 389 378 378 GLU GLU B . n 
B 1 390 ASN 390 379 379 ASN ASN B . n 
B 1 391 LYS 391 380 380 LYS LYS B . n 
B 1 392 ASP 392 381 381 ASP ASP B . n 
B 1 393 CYS 393 382 382 CYS CYS B . n 
B 1 394 VAL 394 383 383 VAL VAL B . n 
B 1 395 ASP 395 384 384 ASP ASP B . n 
B 1 396 THR 396 385 385 THR THR B . n 
B 1 397 ILE 397 386 386 ILE ILE B . n 
B 1 398 TYR 398 387 387 TYR TYR B . n 
B 1 399 TRP 399 388 388 TRP TRP B . n 
B 1 400 GLY 400 389 389 GLY GLY B . n 
B 1 401 LEU 401 390 390 LEU LEU B . n 
B 1 402 GLU 402 391 391 GLU GLU B . n 
B 1 403 GLY 403 392 392 GLY GLY B . n 
B 1 404 GLY 404 393 393 GLY GLY B . n 
B 1 405 TYR 405 394 394 TYR TYR B . n 
B 1 406 ASP 406 395 395 ASP ASP B . n 
B 1 407 ARG 407 396 396 ARG ARG B . n 
B 1 408 THR 408 397 397 THR THR B . n 
B 1 409 MET 409 398 398 MET MET B . n 
B 1 410 TYR 410 399 399 TYR TYR B . n 
B 1 411 GLU 411 400 400 GLU GLU B . n 
B 1 412 ARG 412 401 401 ARG ARG B . n 
B 1 413 GLU 413 402 402 GLU GLU B . n 
B 1 414 LEU 414 403 403 LEU LEU B . n 
B 1 415 LYS 415 404 404 LYS LYS B . n 
B 1 416 ILE 416 405 405 ILE ILE B . n 
B 1 417 LEU 417 406 406 LEU LEU B . n 
B 1 418 LEU 418 407 407 LEU LEU B . n 
B 1 419 GLN 419 408 408 GLN GLN B . n 
B 1 420 VAL 420 409 409 VAL VAL B . n 
B 1 421 ILE 421 410 410 ILE ILE B . n 
B 1 422 GLU 422 411 411 GLU GLU B . n 
B 1 423 LYS 423 412 412 LYS LYS B . n 
B 1 424 GLN 424 413 413 GLN GLN B . n 
B 1 425 LEU 425 414 414 LEU LEU B . n 
B 1 426 LEU 426 415 415 LEU LEU B . n 
B 1 427 PRO 427 416 416 PRO PRO B . n 
B 1 428 LYS 428 417 417 LYS LYS B . n 
B 1 429 ASP 429 418 418 ASP ASP B . n 
B 1 430 SER 430 419 ?   ?   ?   B . n 
B 1 431 ASN 431 420 ?   ?   ?   B . n 
B 1 432 SER 432 421 ?   ?   ?   B . n 
B 1 433 HIS 433 422 ?   ?   ?   B . n 
B 1 434 SER 434 423 ?   ?   ?   B . n 
B 1 435 MET 435 424 ?   ?   ?   B . n 
B 1 436 SER 436 425 ?   ?   ?   B . n 
B 1 437 TYR 437 426 ?   ?   ?   B . n 
C 1 1   MET 1   -10 ?   ?   ?   C . n 
C 1 2   ALA 2   -9  ?   ?   ?   C . n 
C 1 3   HIS 3   -8  ?   ?   ?   C . n 
C 1 4   HIS 4   -7  ?   ?   ?   C . n 
C 1 5   HIS 5   -6  ?   ?   ?   C . n 
C 1 6   HIS 6   -5  ?   ?   ?   C . n 
C 1 7   HIS 7   -4  ?   ?   ?   C . n 
C 1 8   HIS 8   -3  ?   ?   ?   C . n 
C 1 9   VAL 9   -2  ?   ?   ?   C . n 
C 1 10  GLY 10  -1  ?   ?   ?   C . n 
C 1 11  THR 11  0   ?   ?   ?   C . n 
C 1 12  MET 12  1   ?   ?   ?   C . n 
C 1 13  ASP 13  2   ?   ?   ?   C . n 
C 1 14  MET 14  3   ?   ?   ?   C . n 
C 1 15  ALA 15  4   ?   ?   ?   C . n 
C 1 16  LYS 16  5   ?   ?   ?   C . n 
C 1 17  ASP 17  6   ?   ?   ?   C . n 
C 1 18  LYS 18  7   ?   ?   ?   C . n 
C 1 19  GLY 19  8   ?   ?   ?   C . n 
C 1 20  PHE 20  9   ?   ?   ?   C . n 
C 1 21  PHE 21  10  ?   ?   ?   C . n 
C 1 22  LYS 22  11  ?   ?   ?   C . n 
C 1 23  LYS 23  12  ?   ?   ?   C . n 
C 1 24  ALA 24  13  ?   ?   ?   C . n 
C 1 25  LYS 25  14  ?   ?   ?   C . n 
C 1 26  MET 26  15  ?   ?   ?   C . n 
C 1 27  GLU 27  16  ?   ?   ?   C . n 
C 1 28  LYS 28  17  ?   ?   ?   C . n 
C 1 29  ASN 29  18  ?   ?   ?   C . n 
C 1 30  LYS 30  19  ?   ?   ?   C . n 
C 1 31  ARG 31  20  ?   ?   ?   C . n 
C 1 32  LEU 32  21  ?   ?   ?   C . n 
C 1 33  VAL 33  22  ?   ?   ?   C . n 
C 1 34  THR 34  23  ?   ?   ?   C . n 
C 1 35  PRO 35  24  ?   ?   ?   C . n 
C 1 36  TYR 36  25  ?   ?   ?   C . n 
C 1 37  SER 37  26  ?   ?   ?   C . n 
C 1 38  GLU 38  27  27  GLU GLU C . n 
C 1 39  GLU 39  28  28  GLU GLU C . n 
C 1 40  CYS 40  29  29  CYS CYS C . n 
C 1 41  ALA 41  30  30  ALA ALA C . n 
C 1 42  ILE 42  31  31  ILE ILE C . n 
C 1 43  GLN 43  32  32  GLN GLN C . n 
C 1 44  ILE 44  33  33  ILE ILE C . n 
C 1 45  PRO 45  34  34  PRO PRO C . n 
C 1 46  SER 46  35  35  SER SER C . n 
C 1 47  GLU 47  36  36  GLU GLU C . n 
C 1 48  ILE 48  37  37  ILE ILE C . n 
C 1 49  ASP 49  38  38  ASP ASP C . n 
C 1 50  ASN 50  39  39  ASN ASN C . n 
C 1 51  GLU 51  40  40  GLU GLU C . n 
C 1 52  GLN 52  41  41  GLN GLN C . n 
C 1 53  MET 53  42  42  MET MET C . n 
C 1 54  GLN 54  43  43  GLN GLN C . n 
C 1 55  ARG 55  44  44  ARG ARG C . n 
C 1 56  MET 56  45  45  MET MET C . n 
C 1 57  PRO 57  46  46  PRO PRO C . n 
C 1 58  ALA 58  47  47  ALA ALA C . n 
C 1 59  GLY 59  48  48  GLY GLY C . n 
C 1 60  GLY 60  49  49  GLY GLY C . n 
C 1 61  GLU 61  50  50  GLU GLU C . n 
C 1 62  GLU 62  51  51  GLU GLU C . n 
C 1 63  ASP 63  52  52  ASP ASP C . n 
C 1 64  GLN 64  53  53  GLN GLN C . n 
C 1 65  TYR 65  54  54  TYR TYR C . n 
C 1 66  LEU 66  55  55  LEU LEU C . n 
C 1 67  ARG 67  56  56  ARG ARG C . n 
C 1 68  ILE 68  57  57  ILE ILE C . n 
C 1 69  LYS 69  58  58  LYS LYS C . n 
C 1 70  HIS 70  59  59  HIS HIS C . n 
C 1 71  MET 71  60  60  MET MET C . n 
C 1 72  SER 72  61  61  SER SER C . n 
C 1 73  ALA 73  62  62  ALA ALA C . n 
C 1 74  LEU 74  63  63  LEU LEU C . n 
C 1 75  ILE 75  64  64  ILE ILE C . n 
C 1 76  LYS 76  65  65  LYS LYS C . n 
C 1 77  LYS 77  66  66  LYS LYS C . n 
C 1 78  TYR 78  67  67  TYR TYR C . n 
C 1 79  GLY 79  68  68  GLY GLY C . n 
C 1 80  ASP 80  69  69  ASP ASP C . n 
C 1 81  LEU 81  70  70  LEU LEU C . n 
C 1 82  PRO 82  71  71  PRO PRO C . n 
C 1 83  VAL 83  72  72  VAL VAL C . n 
C 1 84  ILE 84  73  73  ILE ILE C . n 
C 1 85  THR 85  74  74  THR THR C . n 
C 1 86  THR 86  75  75  THR THR C . n 
C 1 87  GLN 87  76  76  GLN GLN C . n 
C 1 88  GLU 88  77  77  GLU GLU C . n 
C 1 89  THR 89  78  78  THR THR C . n 
C 1 90  ARG 90  79  79  ARG ARG C . n 
C 1 91  LEU 91  80  80  LEU LEU C . n 
C 1 92  PRO 92  81  81  PRO PRO C . n 
C 1 93  TYR 93  82  82  TYR TYR C . n 
C 1 94  TYR 94  83  83  TYR TYR C . n 
C 1 95  TRP 95  84  84  TRP TRP C . n 
C 1 96  LEU 96  85  85  LEU LEU C . n 
C 1 97  ASP 97  86  86  ASP ASP C . n 
C 1 98  LEU 98  87  87  LEU LEU C . n 
C 1 99  PHE 99  88  88  PHE PHE C . n 
C 1 100 ALA 100 89  89  ALA ALA C . n 
C 1 101 ALA 101 90  90  ALA ALA C . n 
C 1 102 ILE 102 91  91  ILE ILE C . n 
C 1 103 ASP 103 92  92  ASP ASP C . n 
C 1 104 GLU 104 93  93  GLU GLU C . n 
C 1 105 GLY 105 94  94  GLY GLY C . n 
C 1 106 ASP 106 95  95  ASP ASP C . n 
C 1 107 THR 107 96  96  THR THR C . n 
C 1 108 PRO 108 97  97  PRO PRO C . n 
C 1 109 LYS 109 98  98  LYS LYS C . n 
C 1 110 ALA 110 99  99  ALA ALA C . n 
C 1 111 HIS 111 100 100 HIS HIS C . n 
C 1 112 ALA 112 101 101 ALA ALA C . n 
C 1 113 LEU 113 102 102 LEU LEU C . n 
C 1 114 PHE 114 103 103 PHE PHE C . n 
C 1 115 HIS 115 104 104 HIS HIS C . n 
C 1 116 LEU 116 105 105 LEU LEU C . n 
C 1 117 LEU 117 106 106 LEU LEU C . n 
C 1 118 PRO 118 107 107 PRO PRO C . n 
C 1 119 GLN 119 108 108 GLN GLN C . n 
C 1 120 ASP 120 109 109 ASP ASP C . n 
C 1 121 ASP 121 110 110 ASP ASP C . n 
C 1 122 ILE 122 111 111 ILE ILE C . n 
C 1 123 ILE 123 112 112 ILE ILE C . n 
C 1 124 LEU 124 113 113 LEU LEU C . n 
C 1 125 ARG 125 114 114 ARG ARG C . n 
C 1 126 ALA 126 115 115 ALA ALA C . n 
C 1 127 LEU 127 116 116 LEU LEU C . n 
C 1 128 ARG 128 117 117 ARG ARG C . n 
C 1 129 ALA 129 118 118 ALA ALA C . n 
C 1 130 VAL 130 119 119 VAL VAL C . n 
C 1 131 HIS 131 120 120 HIS HIS C . n 
C 1 132 SER 132 121 121 SER SER C . n 
C 1 133 GLU 133 122 122 GLU GLU C . n 
C 1 134 ASP 134 123 123 ASP ASP C . n 
C 1 135 TYR 135 124 124 TYR TYR C . n 
C 1 136 LEU 136 125 125 LEU LEU C . n 
C 1 137 TYR 137 126 126 TYR TYR C . n 
C 1 138 GLN 138 127 127 GLN GLN C . n 
C 1 139 LEU 139 128 128 LEU LEU C . n 
C 1 140 ILE 140 129 129 ILE ILE C . n 
C 1 141 LYS 141 130 130 LYS LYS C . n 
C 1 142 TYR 142 131 131 TYR TYR C . n 
C 1 143 CYS 143 132 132 CYS CYS C . n 
C 1 144 ILE 144 133 133 ILE ILE C . n 
C 1 145 GLN 145 134 134 GLN GLN C . n 
C 1 146 ALA 146 135 135 ALA ALA C . n 
C 1 147 LYS 147 136 136 LYS LYS C . n 
C 1 148 HIS 148 137 137 HIS HIS C . n 
C 1 149 PHE 149 138 138 PHE PHE C . n 
C 1 150 GLY 150 139 139 GLY GLY C . n 
C 1 151 PHE 151 140 140 PHE PHE C . n 
C 1 152 LYS 152 141 141 LYS LYS C . n 
C 1 153 GLN 153 142 142 GLN GLN C . n 
C 1 154 LEU 154 143 143 LEU LEU C . n 
C 1 155 ASN 155 144 144 ASN ASN C . n 
C 1 156 ALA 156 145 145 ALA ALA C . n 
C 1 157 ASP 157 146 146 ASP ASP C . n 
C 1 158 LEU 158 147 147 LEU LEU C . n 
C 1 159 VAL 159 148 148 VAL VAL C . n 
C 1 160 VAL 160 149 149 VAL VAL C . n 
C 1 161 THR 161 150 150 THR THR C . n 
C 1 162 PRO 162 151 151 PRO PRO C . n 
C 1 163 LYS 163 152 152 LYS LYS C . n 
C 1 164 THR 164 153 153 THR THR C . n 
C 1 165 PHE 165 154 154 PHE PHE C . n 
C 1 166 GLU 166 155 155 GLU GLU C . n 
C 1 167 ILE 167 156 156 ILE ILE C . n 
C 1 168 LEU 168 157 157 LEU LEU C . n 
C 1 169 ILE 169 158 158 ILE ILE C . n 
C 1 170 ARG 170 159 159 ARG ARG C . n 
C 1 171 ASP 171 160 160 ASP ASP C . n 
C 1 172 CYS 172 161 161 CYS CYS C . n 
C 1 173 ALA 173 162 162 ALA ALA C . n 
C 1 174 THR 174 163 163 THR THR C . n 
C 1 175 THR 175 164 164 THR THR C . n 
C 1 176 LEU 176 165 165 LEU LEU C . n 
C 1 177 PHE 177 166 166 PHE PHE C . n 
C 1 178 ASN 178 167 167 ASN ASN C . n 
C 1 179 PRO 179 168 168 PRO PRO C . n 
C 1 180 ALA 180 169 169 ALA ALA C . n 
C 1 181 LYS 181 170 170 LYS LYS C . n 
C 1 182 ALA 182 171 171 ALA ALA C . n 
C 1 183 HIS 183 172 172 HIS HIS C . n 
C 1 184 PHE 184 173 173 PHE PHE C . n 
C 1 185 SER 185 174 174 SER SER C . n 
C 1 186 PHE 186 175 175 PHE PHE C . n 
C 1 187 GLY 187 176 176 GLY GLY C . n 
C 1 188 LEU 188 177 177 LEU LEU C . n 
C 1 189 PRO 189 178 178 PRO PRO C . n 
C 1 190 SER 190 179 179 SER SER C . n 
C 1 191 HIS 191 180 180 HIS HIS C . n 
C 1 192 HIS 192 181 181 HIS HIS C . n 
C 1 193 ALA 193 182 182 ALA ALA C . n 
C 1 194 TYR 194 183 183 TYR TYR C . n 
C 1 195 THR 195 184 184 THR THR C . n 
C 1 196 GLN 196 185 185 GLN GLN C . n 
C 1 197 MET 197 186 186 MET MET C . n 
C 1 198 GLY 198 187 187 GLY GLY C . n 
C 1 199 SER 199 188 188 SER SER C . n 
C 1 200 GLY 200 189 189 GLY GLY C . n 
C 1 201 PHE 201 190 190 PHE PHE C . n 
C 1 202 CYS 202 191 191 CYS CYS C . n 
C 1 203 LEU 203 192 192 LEU LEU C . n 
C 1 204 ILE 204 193 193 ILE ILE C . n 
C 1 205 ASN 205 194 194 ASN ASN C . n 
C 1 206 LYS 206 195 195 LYS LYS C . n 
C 1 207 THR 207 196 196 THR THR C . n 
C 1 208 ALA 208 197 197 ALA ALA C . n 
C 1 209 MET 209 198 198 MET MET C . n 
C 1 210 LEU 210 199 199 LEU LEU C . n 
C 1 211 MET 211 200 200 MET MET C . n 
C 1 212 LYS 212 201 201 LYS LYS C . n 
C 1 213 GLN 213 202 202 GLN GLN C . n 
C 1 214 ALA 214 203 203 ALA ALA C . n 
C 1 215 GLU 215 204 204 GLU GLU C . n 
C 1 216 LEU 216 205 205 LEU LEU C . n 
C 1 217 SER 217 206 206 SER SER C . n 
C 1 218 SER 218 207 207 SER SER C . n 
C 1 219 ALA 219 208 208 ALA ALA C . n 
C 1 220 GLN 220 209 209 GLN GLN C . n 
C 1 221 PRO 221 210 210 PRO PRO C . n 
C 1 222 PRO 222 211 211 PRO PRO C . n 
C 1 223 LYS 223 212 212 LYS LYS C . n 
C 1 224 PHE 224 213 213 PHE PHE C . n 
C 1 225 VAL 225 214 214 VAL VAL C . n 
C 1 226 ILE 226 215 215 ILE ILE C . n 
C 1 227 ILE 227 216 216 ILE ILE C . n 
C 1 228 GLY 228 217 217 GLY GLY C . n 
C 1 229 THR 229 218 218 THR THR C . n 
C 1 230 ASP 230 219 219 ASP ASP C . n 
C 1 231 VAL 231 220 220 VAL VAL C . n 
C 1 232 ASN 232 221 221 ASN ASN C . n 
C 1 233 ARG 233 222 222 ARG ARG C . n 
C 1 234 ASP 234 223 223 ASP ASP C . n 
C 1 235 ASN 235 224 224 ASN ASN C . n 
C 1 236 GLY 236 225 225 GLY GLY C . n 
C 1 237 LEU 237 226 226 LEU LEU C . n 
C 1 238 CYS 238 227 227 CYS CYS C . n 
C 1 239 ASP 239 228 228 ASP ASP C . n 
C 1 240 ILE 240 229 229 ILE ILE C . n 
C 1 241 LEU 241 230 230 LEU LEU C . n 
C 1 242 ARG 242 231 231 ARG ARG C . n 
C 1 243 HIS 243 232 232 HIS HIS C . n 
C 1 244 SER 244 233 233 SER SER C . n 
C 1 245 PHE 245 234 234 PHE PHE C . n 
C 1 246 SER 246 235 235 SER SER C . n 
C 1 247 HIS 247 236 236 HIS HIS C . n 
C 1 248 LEU 248 237 237 LEU LEU C . n 
C 1 249 SER 249 238 238 SER SER C . n 
C 1 250 ILE 250 239 239 ILE ILE C . n 
C 1 251 CYS 251 240 240 CYS CYS C . n 
C 1 252 HIS 252 241 241 HIS HIS C . n 
C 1 253 ILE 253 242 242 ILE ILE C . n 
C 1 254 ASP 254 243 243 ASP ASP C . n 
C 1 255 VAL 255 244 244 VAL VAL C . n 
C 1 256 PHE 256 245 245 PHE PHE C . n 
C 1 257 ASP 257 246 246 ASP ASP C . n 
C 1 258 SER 258 247 247 SER SER C . n 
C 1 259 ARG 259 248 248 ARG ARG C . n 
C 1 260 VAL 260 249 249 VAL VAL C . n 
C 1 261 TYR 261 250 250 TYR TYR C . n 
C 1 262 PRO 262 251 251 PRO PRO C . n 
C 1 263 GLN 263 252 252 GLN GLN C . n 
C 1 264 GLN 264 253 253 GLN GLN C . n 
C 1 265 ASP 265 254 254 ASP ASP C . n 
C 1 266 PHE 266 255 255 PHE PHE C . n 
C 1 267 ALA 267 256 256 ALA ALA C . n 
C 1 268 TYR 268 257 257 TYR TYR C . n 
C 1 269 ILE 269 258 258 ILE ILE C . n 
C 1 270 ASN 270 259 259 ASN ASN C . n 
C 1 271 ASN 271 260 260 ASN ASN C . n 
C 1 272 GLU 272 261 261 GLU GLU C . n 
C 1 273 PHE 273 262 262 PHE PHE C . n 
C 1 274 ASN 274 263 263 ASN ASN C . n 
C 1 275 SER 275 264 264 SER SER C . n 
C 1 276 GLU 276 265 265 GLU GLU C . n 
C 1 277 GLY 277 266 266 GLY GLY C . n 
C 1 278 VAL 278 267 267 VAL VAL C . n 
C 1 279 ASP 279 268 268 ASP ASP C . n 
C 1 280 ILE 280 269 269 ILE ILE C . n 
C 1 281 GLY 281 270 270 GLY GLY C . n 
C 1 282 LYS 282 271 271 LYS LYS C . n 
C 1 283 ASN 283 272 272 ASN ASN C . n 
C 1 284 ILE 284 273 273 ILE ILE C . n 
C 1 285 HIS 285 274 274 HIS HIS C . n 
C 1 286 VAL 286 275 275 VAL VAL C . n 
C 1 287 TRP 287 276 276 TRP TRP C . n 
C 1 288 HIS 288 277 277 HIS HIS C . n 
C 1 289 HIS 289 278 278 HIS HIS C . n 
C 1 290 ASN 290 279 279 ASN ASN C . n 
C 1 291 ASN 291 280 280 ASN ASN C . n 
C 1 292 LEU 292 281 281 LEU LEU C . n 
C 1 293 ASN 293 282 282 ASN ASN C . n 
C 1 294 TYR 294 283 283 TYR TYR C . n 
C 1 295 TYR 295 284 284 TYR TYR C . n 
C 1 296 ALA 296 285 285 ALA ALA C . n 
C 1 297 VAL 297 286 286 VAL VAL C . n 
C 1 298 ASP 298 287 287 ASP ASP C . n 
C 1 299 LEU 299 288 288 LEU LEU C . n 
C 1 300 SER 300 289 289 SER SER C . n 
C 1 301 LEU 301 290 290 LEU LEU C . n 
C 1 302 THR 302 291 291 THR THR C . n 
C 1 303 SER 303 292 292 SER SER C . n 
C 1 304 ARG 304 293 293 ARG ARG C . n 
C 1 305 LYS 305 294 294 LYS LYS C . n 
C 1 306 SER 306 295 295 SER SER C . n 
C 1 307 VAL 307 296 296 VAL VAL C . n 
C 1 308 GLY 308 297 297 GLY GLY C . n 
C 1 309 VAL 309 298 298 VAL VAL C . n 
C 1 310 HIS 310 299 299 HIS HIS C . n 
C 1 311 PRO 311 300 300 PRO PRO C . n 
C 1 312 ALA 312 301 301 ALA ALA C . n 
C 1 313 LEU 313 302 302 LEU LEU C . n 
C 1 314 LEU 314 303 303 LEU LEU C . n 
C 1 315 PHE 315 304 304 PHE PHE C . n 
C 1 316 ALA 316 305 305 ALA ALA C . n 
C 1 317 LEU 317 306 306 LEU LEU C . n 
C 1 318 GLU 318 307 307 GLU GLU C . n 
C 1 319 GLN 319 308 308 GLN GLN C . n 
C 1 320 LEU 320 309 309 LEU LEU C . n 
C 1 321 LYS 321 310 310 LYS LYS C . n 
C 1 322 GLU 322 311 311 GLU GLU C . n 
C 1 323 SER 323 312 312 SER SER C . n 
C 1 324 ILE 324 313 313 ILE ILE C . n 
C 1 325 ARG 325 314 314 ARG ARG C . n 
C 1 326 GLU 326 315 315 GLU GLU C . n 
C 1 327 ALA 327 316 316 ALA ALA C . n 
C 1 328 LYS 328 317 317 LYS LYS C . n 
C 1 329 ALA 329 318 318 ALA ALA C . n 
C 1 330 LYS 330 319 319 LYS LYS C . n 
C 1 331 GLY 331 320 320 GLY GLY C . n 
C 1 332 GLN 332 321 321 GLN GLN C . n 
C 1 333 LYS 333 322 322 LYS LYS C . n 
C 1 334 ILE 334 323 323 ILE ILE C . n 
C 1 335 ALA 335 324 324 ALA ALA C . n 
C 1 336 LEU 336 325 325 LEU LEU C . n 
C 1 337 TYR 337 326 326 TYR TYR C . n 
C 1 338 LEU 338 327 327 LEU LEU C . n 
C 1 339 PRO 339 328 328 PRO PRO C . n 
C 1 340 THR 340 329 329 THR THR C . n 
C 1 341 GLY 341 330 330 GLY GLY C . n 
C 1 342 TRP 342 331 331 TRP TRP C . n 
C 1 343 ASP 343 332 332 ASP ASP C . n 
C 1 344 SER 344 333 333 SER SER C . n 
C 1 345 HIS 345 334 334 HIS HIS C . n 
C 1 346 GLU 346 335 335 GLU GLU C . n 
C 1 347 ASP 347 336 336 ASP ASP C . n 
C 1 348 GLU 348 337 337 GLU GLU C . n 
C 1 349 THR 349 338 338 THR THR C . n 
C 1 350 ALA 350 339 339 ALA ALA C . n 
C 1 351 TYR 351 340 340 TYR TYR C . n 
C 1 352 CYS 352 341 341 CYS CYS C . n 
C 1 353 GLY 353 342 342 GLY GLY C . n 
C 1 354 LYS 354 343 343 LYS LYS C . n 
C 1 355 PHE 355 344 344 PHE PHE C . n 
C 1 356 VAL 356 345 345 VAL VAL C . n 
C 1 357 ASN 357 346 346 ASN ASN C . n 
C 1 358 GLY 358 347 347 GLY GLY C . n 
C 1 359 ARG 359 348 348 ARG ARG C . n 
C 1 360 MET 360 349 349 MET MET C . n 
C 1 361 MET 361 350 350 MET MET C . n 
C 1 362 GLY 362 351 351 GLY GLY C . n 
C 1 363 LYS 363 352 352 LYS LYS C . n 
C 1 364 THR 364 353 353 THR THR C . n 
C 1 365 ALA 365 354 354 ALA ALA C . n 
C 1 366 ALA 366 355 355 ALA ALA C . n 
C 1 367 HIS 367 356 356 HIS HIS C . n 
C 1 368 GLN 368 357 357 GLN GLN C . n 
C 1 369 PHE 369 358 358 PHE PHE C . n 
C 1 370 ARG 370 359 359 ARG ARG C . n 
C 1 371 PHE 371 360 360 PHE PHE C . n 
C 1 372 ASN 372 361 361 ASN ASN C . n 
C 1 373 ASP 373 362 362 ASP ASP C . n 
C 1 374 GLY 374 363 363 GLY GLY C . n 
C 1 375 ASP 375 364 364 ASP ASP C . n 
C 1 376 LEU 376 365 365 LEU LEU C . n 
C 1 377 GLY 377 366 366 GLY GLY C . n 
C 1 378 TYR 378 367 367 TYR TYR C . n 
C 1 379 PHE 379 368 368 PHE PHE C . n 
C 1 380 TYR 380 369 369 TYR TYR C . n 
C 1 381 GLU 381 370 370 GLU GLU C . n 
C 1 382 SER 382 371 371 SER SER C . n 
C 1 383 ILE 383 372 372 ILE ILE C . n 
C 1 384 PHE 384 373 373 PHE PHE C . n 
C 1 385 THR 385 374 374 THR THR C . n 
C 1 386 LEU 386 375 375 LEU LEU C . n 
C 1 387 TYR 387 376 376 TYR TYR C . n 
C 1 388 ASN 388 377 377 ASN ASN C . n 
C 1 389 GLU 389 378 378 GLU GLU C . n 
C 1 390 ASN 390 379 379 ASN ASN C . n 
C 1 391 LYS 391 380 380 LYS LYS C . n 
C 1 392 ASP 392 381 381 ASP ASP C . n 
C 1 393 CYS 393 382 382 CYS CYS C . n 
C 1 394 VAL 394 383 383 VAL VAL C . n 
C 1 395 ASP 395 384 384 ASP ASP C . n 
C 1 396 THR 396 385 385 THR THR C . n 
C 1 397 ILE 397 386 386 ILE ILE C . n 
C 1 398 TYR 398 387 387 TYR TYR C . n 
C 1 399 TRP 399 388 388 TRP TRP C . n 
C 1 400 GLY 400 389 389 GLY GLY C . n 
C 1 401 LEU 401 390 390 LEU LEU C . n 
C 1 402 GLU 402 391 391 GLU GLU C . n 
C 1 403 GLY 403 392 392 GLY GLY C . n 
C 1 404 GLY 404 393 393 GLY GLY C . n 
C 1 405 TYR 405 394 394 TYR TYR C . n 
C 1 406 ASP 406 395 395 ASP ASP C . n 
C 1 407 ARG 407 396 396 ARG ARG C . n 
C 1 408 THR 408 397 397 THR THR C . n 
C 1 409 MET 409 398 398 MET MET C . n 
C 1 410 TYR 410 399 399 TYR TYR C . n 
C 1 411 GLU 411 400 400 GLU GLU C . n 
C 1 412 ARG 412 401 401 ARG ARG C . n 
C 1 413 GLU 413 402 402 GLU GLU C . n 
C 1 414 LEU 414 403 403 LEU LEU C . n 
C 1 415 LYS 415 404 404 LYS LYS C . n 
C 1 416 ILE 416 405 405 ILE ILE C . n 
C 1 417 LEU 417 406 406 LEU LEU C . n 
C 1 418 LEU 418 407 407 LEU LEU C . n 
C 1 419 GLN 419 408 408 GLN GLN C . n 
C 1 420 VAL 420 409 409 VAL VAL C . n 
C 1 421 ILE 421 410 410 ILE ILE C . n 
C 1 422 GLU 422 411 411 GLU GLU C . n 
C 1 423 LYS 423 412 412 LYS LYS C . n 
C 1 424 GLN 424 413 413 GLN GLN C . n 
C 1 425 LEU 425 414 414 LEU LEU C . n 
C 1 426 LEU 426 415 415 LEU LEU C . n 
C 1 427 PRO 427 416 416 PRO PRO C . n 
C 1 428 LYS 428 417 417 LYS LYS C . n 
C 1 429 ASP 429 418 418 ASP ALA C . n 
C 1 430 SER 430 419 ?   ?   ?   C . n 
C 1 431 ASN 431 420 ?   ?   ?   C . n 
C 1 432 SER 432 421 ?   ?   ?   C . n 
C 1 433 HIS 433 422 ?   ?   ?   C . n 
C 1 434 SER 434 423 ?   ?   ?   C . n 
C 1 435 MET 435 424 ?   ?   ?   C . n 
C 1 436 SER 436 425 ?   ?   ?   C . n 
C 1 437 TYR 437 426 ?   ?   ?   C . n 
D 1 1   MET 1   -10 ?   ?   ?   D . n 
D 1 2   ALA 2   -9  ?   ?   ?   D . n 
D 1 3   HIS 3   -8  ?   ?   ?   D . n 
D 1 4   HIS 4   -7  ?   ?   ?   D . n 
D 1 5   HIS 5   -6  ?   ?   ?   D . n 
D 1 6   HIS 6   -5  ?   ?   ?   D . n 
D 1 7   HIS 7   -4  ?   ?   ?   D . n 
D 1 8   HIS 8   -3  ?   ?   ?   D . n 
D 1 9   VAL 9   -2  ?   ?   ?   D . n 
D 1 10  GLY 10  -1  ?   ?   ?   D . n 
D 1 11  THR 11  0   ?   ?   ?   D . n 
D 1 12  MET 12  1   ?   ?   ?   D . n 
D 1 13  ASP 13  2   ?   ?   ?   D . n 
D 1 14  MET 14  3   ?   ?   ?   D . n 
D 1 15  ALA 15  4   ?   ?   ?   D . n 
D 1 16  LYS 16  5   ?   ?   ?   D . n 
D 1 17  ASP 17  6   ?   ?   ?   D . n 
D 1 18  LYS 18  7   ?   ?   ?   D . n 
D 1 19  GLY 19  8   ?   ?   ?   D . n 
D 1 20  PHE 20  9   ?   ?   ?   D . n 
D 1 21  PHE 21  10  ?   ?   ?   D . n 
D 1 22  LYS 22  11  ?   ?   ?   D . n 
D 1 23  LYS 23  12  ?   ?   ?   D . n 
D 1 24  ALA 24  13  ?   ?   ?   D . n 
D 1 25  LYS 25  14  ?   ?   ?   D . n 
D 1 26  MET 26  15  ?   ?   ?   D . n 
D 1 27  GLU 27  16  ?   ?   ?   D . n 
D 1 28  LYS 28  17  ?   ?   ?   D . n 
D 1 29  ASN 29  18  ?   ?   ?   D . n 
D 1 30  LYS 30  19  ?   ?   ?   D . n 
D 1 31  ARG 31  20  ?   ?   ?   D . n 
D 1 32  LEU 32  21  ?   ?   ?   D . n 
D 1 33  VAL 33  22  ?   ?   ?   D . n 
D 1 34  THR 34  23  ?   ?   ?   D . n 
D 1 35  PRO 35  24  ?   ?   ?   D . n 
D 1 36  TYR 36  25  ?   ?   ?   D . n 
D 1 37  SER 37  26  ?   ?   ?   D . n 
D 1 38  GLU 38  27  27  GLU GLU D . n 
D 1 39  GLU 39  28  28  GLU GLU D . n 
D 1 40  CYS 40  29  29  CYS CYS D . n 
D 1 41  ALA 41  30  30  ALA ALA D . n 
D 1 42  ILE 42  31  31  ILE ILE D . n 
D 1 43  GLN 43  32  32  GLN GLN D . n 
D 1 44  ILE 44  33  33  ILE ILE D . n 
D 1 45  PRO 45  34  34  PRO PRO D . n 
D 1 46  SER 46  35  35  SER SER D . n 
D 1 47  GLU 47  36  36  GLU GLU D . n 
D 1 48  ILE 48  37  37  ILE ILE D . n 
D 1 49  ASP 49  38  38  ASP ASP D . n 
D 1 50  ASN 50  39  39  ASN ASN D . n 
D 1 51  GLU 51  40  40  GLU GLU D . n 
D 1 52  GLN 52  41  41  GLN GLN D . n 
D 1 53  MET 53  42  42  MET MET D . n 
D 1 54  GLN 54  43  43  GLN GLN D . n 
D 1 55  ARG 55  44  44  ARG ARG D . n 
D 1 56  MET 56  45  45  MET MET D . n 
D 1 57  PRO 57  46  46  PRO PRO D . n 
D 1 58  ALA 58  47  47  ALA ALA D . n 
D 1 59  GLY 59  48  48  GLY GLY D . n 
D 1 60  GLY 60  49  49  GLY GLY D . n 
D 1 61  GLU 61  50  50  GLU GLU D . n 
D 1 62  GLU 62  51  51  GLU GLU D . n 
D 1 63  ASP 63  52  52  ASP ASP D . n 
D 1 64  GLN 64  53  53  GLN GLN D . n 
D 1 65  TYR 65  54  54  TYR TYR D . n 
D 1 66  LEU 66  55  55  LEU LEU D . n 
D 1 67  ARG 67  56  56  ARG ARG D . n 
D 1 68  ILE 68  57  57  ILE ILE D . n 
D 1 69  LYS 69  58  58  LYS LYS D . n 
D 1 70  HIS 70  59  59  HIS HIS D . n 
D 1 71  MET 71  60  60  MET MET D . n 
D 1 72  SER 72  61  61  SER SER D . n 
D 1 73  ALA 73  62  62  ALA ALA D . n 
D 1 74  LEU 74  63  63  LEU LEU D . n 
D 1 75  ILE 75  64  64  ILE ILE D . n 
D 1 76  LYS 76  65  65  LYS LYS D . n 
D 1 77  LYS 77  66  66  LYS LYS D . n 
D 1 78  TYR 78  67  67  TYR TYR D . n 
D 1 79  GLY 79  68  68  GLY GLY D . n 
D 1 80  ASP 80  69  69  ASP ASP D . n 
D 1 81  LEU 81  70  70  LEU LEU D . n 
D 1 82  PRO 82  71  71  PRO PRO D . n 
D 1 83  VAL 83  72  72  VAL VAL D . n 
D 1 84  ILE 84  73  73  ILE ILE D . n 
D 1 85  THR 85  74  74  THR THR D . n 
D 1 86  THR 86  75  75  THR THR D . n 
D 1 87  GLN 87  76  76  GLN GLN D . n 
D 1 88  GLU 88  77  77  GLU GLU D . n 
D 1 89  THR 89  78  78  THR THR D . n 
D 1 90  ARG 90  79  79  ARG ARG D . n 
D 1 91  LEU 91  80  80  LEU LEU D . n 
D 1 92  PRO 92  81  81  PRO PRO D . n 
D 1 93  TYR 93  82  82  TYR TYR D . n 
D 1 94  TYR 94  83  83  TYR TYR D . n 
D 1 95  TRP 95  84  84  TRP TRP D . n 
D 1 96  LEU 96  85  85  LEU LEU D . n 
D 1 97  ASP 97  86  86  ASP ASP D . n 
D 1 98  LEU 98  87  87  LEU LEU D . n 
D 1 99  PHE 99  88  88  PHE PHE D . n 
D 1 100 ALA 100 89  89  ALA ALA D . n 
D 1 101 ALA 101 90  90  ALA ALA D . n 
D 1 102 ILE 102 91  91  ILE ILE D . n 
D 1 103 ASP 103 92  92  ASP ASP D . n 
D 1 104 GLU 104 93  93  GLU GLU D . n 
D 1 105 GLY 105 94  94  GLY GLY D . n 
D 1 106 ASP 106 95  95  ASP ASP D . n 
D 1 107 THR 107 96  96  THR THR D . n 
D 1 108 PRO 108 97  97  PRO PRO D . n 
D 1 109 LYS 109 98  98  LYS LYS D . n 
D 1 110 ALA 110 99  99  ALA ALA D . n 
D 1 111 HIS 111 100 100 HIS HIS D . n 
D 1 112 ALA 112 101 101 ALA ALA D . n 
D 1 113 LEU 113 102 102 LEU LEU D . n 
D 1 114 PHE 114 103 103 PHE PHE D . n 
D 1 115 HIS 115 104 104 HIS HIS D . n 
D 1 116 LEU 116 105 105 LEU LEU D . n 
D 1 117 LEU 117 106 106 LEU LEU D . n 
D 1 118 PRO 118 107 107 PRO PRO D . n 
D 1 119 GLN 119 108 108 GLN GLN D . n 
D 1 120 ASP 120 109 109 ASP ASP D . n 
D 1 121 ASP 121 110 110 ASP ASP D . n 
D 1 122 ILE 122 111 111 ILE ILE D . n 
D 1 123 ILE 123 112 112 ILE ILE D . n 
D 1 124 LEU 124 113 113 LEU LEU D . n 
D 1 125 ARG 125 114 114 ARG ARG D . n 
D 1 126 ALA 126 115 115 ALA ALA D . n 
D 1 127 LEU 127 116 116 LEU LEU D . n 
D 1 128 ARG 128 117 117 ARG ARG D . n 
D 1 129 ALA 129 118 118 ALA ALA D . n 
D 1 130 VAL 130 119 119 VAL VAL D . n 
D 1 131 HIS 131 120 120 HIS HIS D . n 
D 1 132 SER 132 121 121 SER SER D . n 
D 1 133 GLU 133 122 122 GLU GLU D . n 
D 1 134 ASP 134 123 123 ASP ASP D . n 
D 1 135 TYR 135 124 124 TYR TYR D . n 
D 1 136 LEU 136 125 125 LEU LEU D . n 
D 1 137 TYR 137 126 126 TYR TYR D . n 
D 1 138 GLN 138 127 127 GLN GLN D . n 
D 1 139 LEU 139 128 128 LEU LEU D . n 
D 1 140 ILE 140 129 129 ILE ILE D . n 
D 1 141 LYS 141 130 130 LYS LYS D . n 
D 1 142 TYR 142 131 131 TYR TYR D . n 
D 1 143 CYS 143 132 132 CYS CYS D . n 
D 1 144 ILE 144 133 133 ILE ILE D . n 
D 1 145 GLN 145 134 134 GLN GLN D . n 
D 1 146 ALA 146 135 135 ALA ALA D . n 
D 1 147 LYS 147 136 136 LYS LYS D . n 
D 1 148 HIS 148 137 137 HIS HIS D . n 
D 1 149 PHE 149 138 138 PHE PHE D . n 
D 1 150 GLY 150 139 139 GLY GLY D . n 
D 1 151 PHE 151 140 140 PHE PHE D . n 
D 1 152 LYS 152 141 141 LYS LYS D . n 
D 1 153 GLN 153 142 142 GLN GLN D . n 
D 1 154 LEU 154 143 143 LEU LEU D . n 
D 1 155 ASN 155 144 144 ASN ASN D . n 
D 1 156 ALA 156 145 145 ALA ALA D . n 
D 1 157 ASP 157 146 146 ASP ASP D . n 
D 1 158 LEU 158 147 147 LEU LEU D . n 
D 1 159 VAL 159 148 148 VAL VAL D . n 
D 1 160 VAL 160 149 149 VAL VAL D . n 
D 1 161 THR 161 150 150 THR THR D . n 
D 1 162 PRO 162 151 151 PRO PRO D . n 
D 1 163 LYS 163 152 152 LYS LYS D . n 
D 1 164 THR 164 153 153 THR THR D . n 
D 1 165 PHE 165 154 154 PHE PHE D . n 
D 1 166 GLU 166 155 155 GLU GLU D . n 
D 1 167 ILE 167 156 156 ILE ILE D . n 
D 1 168 LEU 168 157 157 LEU LEU D . n 
D 1 169 ILE 169 158 158 ILE ILE D . n 
D 1 170 ARG 170 159 159 ARG ARG D . n 
D 1 171 ASP 171 160 160 ASP ASP D . n 
D 1 172 CYS 172 161 161 CYS CYS D . n 
D 1 173 ALA 173 162 162 ALA ALA D . n 
D 1 174 THR 174 163 163 THR THR D . n 
D 1 175 THR 175 164 164 THR THR D . n 
D 1 176 LEU 176 165 165 LEU LEU D . n 
D 1 177 PHE 177 166 166 PHE PHE D . n 
D 1 178 ASN 178 167 167 ASN ASN D . n 
D 1 179 PRO 179 168 168 PRO PRO D . n 
D 1 180 ALA 180 169 169 ALA ALA D . n 
D 1 181 LYS 181 170 170 LYS LYS D . n 
D 1 182 ALA 182 171 171 ALA ALA D . n 
D 1 183 HIS 183 172 172 HIS HIS D . n 
D 1 184 PHE 184 173 173 PHE PHE D . n 
D 1 185 SER 185 174 174 SER SER D . n 
D 1 186 PHE 186 175 175 PHE PHE D . n 
D 1 187 GLY 187 176 176 GLY GLY D . n 
D 1 188 LEU 188 177 177 LEU LEU D . n 
D 1 189 PRO 189 178 178 PRO PRO D . n 
D 1 190 SER 190 179 179 SER SER D . n 
D 1 191 HIS 191 180 180 HIS HIS D . n 
D 1 192 HIS 192 181 181 HIS HIS D . n 
D 1 193 ALA 193 182 182 ALA ALA D . n 
D 1 194 TYR 194 183 183 TYR TYR D . n 
D 1 195 THR 195 184 184 THR THR D . n 
D 1 196 GLN 196 185 185 GLN GLN D . n 
D 1 197 MET 197 186 186 MET MET D . n 
D 1 198 GLY 198 187 187 GLY GLY D . n 
D 1 199 SER 199 188 188 SER SER D . n 
D 1 200 GLY 200 189 189 GLY GLY D . n 
D 1 201 PHE 201 190 190 PHE PHE D . n 
D 1 202 CYS 202 191 191 CYS CYS D . n 
D 1 203 LEU 203 192 192 LEU LEU D . n 
D 1 204 ILE 204 193 193 ILE ILE D . n 
D 1 205 ASN 205 194 194 ASN ASN D . n 
D 1 206 LYS 206 195 195 LYS LYS D . n 
D 1 207 THR 207 196 196 THR THR D . n 
D 1 208 ALA 208 197 197 ALA ALA D . n 
D 1 209 MET 209 198 198 MET MET D . n 
D 1 210 LEU 210 199 199 LEU LEU D . n 
D 1 211 MET 211 200 200 MET MET D . n 
D 1 212 LYS 212 201 201 LYS LYS D . n 
D 1 213 GLN 213 202 202 GLN GLN D . n 
D 1 214 ALA 214 203 203 ALA ALA D . n 
D 1 215 GLU 215 204 204 GLU GLU D . n 
D 1 216 LEU 216 205 205 LEU LEU D . n 
D 1 217 SER 217 206 206 SER SER D . n 
D 1 218 SER 218 207 207 SER SER D . n 
D 1 219 ALA 219 208 208 ALA ALA D . n 
D 1 220 GLN 220 209 209 GLN GLN D . n 
D 1 221 PRO 221 210 210 PRO PRO D . n 
D 1 222 PRO 222 211 211 PRO PRO D . n 
D 1 223 LYS 223 212 212 LYS LYS D . n 
D 1 224 PHE 224 213 213 PHE PHE D . n 
D 1 225 VAL 225 214 214 VAL VAL D . n 
D 1 226 ILE 226 215 215 ILE ILE D . n 
D 1 227 ILE 227 216 216 ILE ILE D . n 
D 1 228 GLY 228 217 217 GLY GLY D . n 
D 1 229 THR 229 218 218 THR THR D . n 
D 1 230 ASP 230 219 219 ASP ASP D . n 
D 1 231 VAL 231 220 220 VAL VAL D . n 
D 1 232 ASN 232 221 221 ASN ASN D . n 
D 1 233 ARG 233 222 222 ARG ARG D . n 
D 1 234 ASP 234 223 223 ASP ASP D . n 
D 1 235 ASN 235 224 224 ASN ASN D . n 
D 1 236 GLY 236 225 225 GLY GLY D . n 
D 1 237 LEU 237 226 226 LEU LEU D . n 
D 1 238 CYS 238 227 227 CYS CYS D . n 
D 1 239 ASP 239 228 228 ASP ASP D . n 
D 1 240 ILE 240 229 229 ILE ILE D . n 
D 1 241 LEU 241 230 230 LEU LEU D . n 
D 1 242 ARG 242 231 231 ARG ARG D . n 
D 1 243 HIS 243 232 232 HIS HIS D . n 
D 1 244 SER 244 233 233 SER SER D . n 
D 1 245 PHE 245 234 234 PHE PHE D . n 
D 1 246 SER 246 235 235 SER SER D . n 
D 1 247 HIS 247 236 236 HIS HIS D . n 
D 1 248 LEU 248 237 237 LEU LEU D . n 
D 1 249 SER 249 238 238 SER SER D . n 
D 1 250 ILE 250 239 239 ILE ILE D . n 
D 1 251 CYS 251 240 240 CYS CYS D . n 
D 1 252 HIS 252 241 241 HIS HIS D . n 
D 1 253 ILE 253 242 242 ILE ILE D . n 
D 1 254 ASP 254 243 243 ASP ASP D . n 
D 1 255 VAL 255 244 244 VAL VAL D . n 
D 1 256 PHE 256 245 245 PHE PHE D . n 
D 1 257 ASP 257 246 246 ASP ASP D . n 
D 1 258 SER 258 247 247 SER SER D . n 
D 1 259 ARG 259 248 248 ARG ARG D . n 
D 1 260 VAL 260 249 249 VAL VAL D . n 
D 1 261 TYR 261 250 250 TYR TYR D . n 
D 1 262 PRO 262 251 251 PRO PRO D . n 
D 1 263 GLN 263 252 252 GLN GLN D . n 
D 1 264 GLN 264 253 253 GLN GLN D . n 
D 1 265 ASP 265 254 254 ASP ASP D . n 
D 1 266 PHE 266 255 255 PHE PHE D . n 
D 1 267 ALA 267 256 256 ALA ALA D . n 
D 1 268 TYR 268 257 257 TYR TYR D . n 
D 1 269 ILE 269 258 258 ILE ILE D . n 
D 1 270 ASN 270 259 259 ASN ASN D . n 
D 1 271 ASN 271 260 260 ASN ASN D . n 
D 1 272 GLU 272 261 261 GLU GLU D . n 
D 1 273 PHE 273 262 262 PHE PHE D . n 
D 1 274 ASN 274 263 263 ASN ASN D . n 
D 1 275 SER 275 264 264 SER SER D . n 
D 1 276 GLU 276 265 265 GLU GLU D . n 
D 1 277 GLY 277 266 266 GLY GLY D . n 
D 1 278 VAL 278 267 267 VAL VAL D . n 
D 1 279 ASP 279 268 268 ASP ASP D . n 
D 1 280 ILE 280 269 269 ILE ILE D . n 
D 1 281 GLY 281 270 270 GLY GLY D . n 
D 1 282 LYS 282 271 271 LYS LYS D . n 
D 1 283 ASN 283 272 272 ASN ASN D . n 
D 1 284 ILE 284 273 273 ILE ILE D . n 
D 1 285 HIS 285 274 274 HIS HIS D . n 
D 1 286 VAL 286 275 275 VAL VAL D . n 
D 1 287 TRP 287 276 276 TRP TRP D . n 
D 1 288 HIS 288 277 277 HIS HIS D . n 
D 1 289 HIS 289 278 278 HIS HIS D . n 
D 1 290 ASN 290 279 279 ASN ASN D . n 
D 1 291 ASN 291 280 280 ASN ASN D . n 
D 1 292 LEU 292 281 281 LEU LEU D . n 
D 1 293 ASN 293 282 282 ASN ASN D . n 
D 1 294 TYR 294 283 283 TYR TYR D . n 
D 1 295 TYR 295 284 284 TYR TYR D . n 
D 1 296 ALA 296 285 285 ALA ALA D . n 
D 1 297 VAL 297 286 286 VAL VAL D . n 
D 1 298 ASP 298 287 287 ASP ASP D . n 
D 1 299 LEU 299 288 288 LEU LEU D . n 
D 1 300 SER 300 289 289 SER SER D . n 
D 1 301 LEU 301 290 290 LEU LEU D . n 
D 1 302 THR 302 291 291 THR THR D . n 
D 1 303 SER 303 292 292 SER SER D . n 
D 1 304 ARG 304 293 293 ARG ARG D . n 
D 1 305 LYS 305 294 294 LYS LYS D . n 
D 1 306 SER 306 295 295 SER SER D . n 
D 1 307 VAL 307 296 296 VAL VAL D . n 
D 1 308 GLY 308 297 297 GLY GLY D . n 
D 1 309 VAL 309 298 298 VAL VAL D . n 
D 1 310 HIS 310 299 299 HIS HIS D . n 
D 1 311 PRO 311 300 300 PRO PRO D . n 
D 1 312 ALA 312 301 301 ALA ALA D . n 
D 1 313 LEU 313 302 302 LEU LEU D . n 
D 1 314 LEU 314 303 303 LEU LEU D . n 
D 1 315 PHE 315 304 304 PHE PHE D . n 
D 1 316 ALA 316 305 305 ALA ALA D . n 
D 1 317 LEU 317 306 306 LEU LEU D . n 
D 1 318 GLU 318 307 307 GLU GLU D . n 
D 1 319 GLN 319 308 308 GLN GLN D . n 
D 1 320 LEU 320 309 309 LEU LEU D . n 
D 1 321 LYS 321 310 310 LYS LYS D . n 
D 1 322 GLU 322 311 311 GLU GLU D . n 
D 1 323 SER 323 312 312 SER SER D . n 
D 1 324 ILE 324 313 313 ILE ILE D . n 
D 1 325 ARG 325 314 314 ARG ARG D . n 
D 1 326 GLU 326 315 315 GLU GLU D . n 
D 1 327 ALA 327 316 316 ALA ALA D . n 
D 1 328 LYS 328 317 317 LYS LYS D . n 
D 1 329 ALA 329 318 318 ALA ALA D . n 
D 1 330 LYS 330 319 319 LYS LYS D . n 
D 1 331 GLY 331 320 320 GLY GLY D . n 
D 1 332 GLN 332 321 321 GLN GLN D . n 
D 1 333 LYS 333 322 322 LYS LYS D . n 
D 1 334 ILE 334 323 323 ILE ILE D . n 
D 1 335 ALA 335 324 324 ALA ALA D . n 
D 1 336 LEU 336 325 325 LEU LEU D . n 
D 1 337 TYR 337 326 326 TYR TYR D . n 
D 1 338 LEU 338 327 327 LEU LEU D . n 
D 1 339 PRO 339 328 328 PRO PRO D . n 
D 1 340 THR 340 329 329 THR THR D . n 
D 1 341 GLY 341 330 330 GLY GLY D . n 
D 1 342 TRP 342 331 331 TRP TRP D . n 
D 1 343 ASP 343 332 332 ASP ASP D . n 
D 1 344 SER 344 333 333 SER SER D . n 
D 1 345 HIS 345 334 334 HIS HIS D . n 
D 1 346 GLU 346 335 335 GLU GLU D . n 
D 1 347 ASP 347 336 336 ASP ASP D . n 
D 1 348 GLU 348 337 337 GLU GLU D . n 
D 1 349 THR 349 338 338 THR THR D . n 
D 1 350 ALA 350 339 339 ALA ALA D . n 
D 1 351 TYR 351 340 340 TYR TYR D . n 
D 1 352 CYS 352 341 341 CYS CYS D . n 
D 1 353 GLY 353 342 342 GLY GLY D . n 
D 1 354 LYS 354 343 343 LYS LYS D . n 
D 1 355 PHE 355 344 344 PHE PHE D . n 
D 1 356 VAL 356 345 345 VAL VAL D . n 
D 1 357 ASN 357 346 346 ASN ASN D . n 
D 1 358 GLY 358 347 347 GLY GLY D . n 
D 1 359 ARG 359 348 348 ARG ARG D . n 
D 1 360 MET 360 349 349 MET MET D . n 
D 1 361 MET 361 350 350 MET MET D . n 
D 1 362 GLY 362 351 351 GLY GLY D . n 
D 1 363 LYS 363 352 352 LYS LYS D . n 
D 1 364 THR 364 353 353 THR THR D . n 
D 1 365 ALA 365 354 354 ALA ALA D . n 
D 1 366 ALA 366 355 355 ALA ALA D . n 
D 1 367 HIS 367 356 356 HIS HIS D . n 
D 1 368 GLN 368 357 357 GLN GLN D . n 
D 1 369 PHE 369 358 358 PHE PHE D . n 
D 1 370 ARG 370 359 359 ARG ARG D . n 
D 1 371 PHE 371 360 360 PHE PHE D . n 
D 1 372 ASN 372 361 361 ASN ASN D . n 
D 1 373 ASP 373 362 362 ASP ASP D . n 
D 1 374 GLY 374 363 363 GLY GLY D . n 
D 1 375 ASP 375 364 364 ASP ASP D . n 
D 1 376 LEU 376 365 365 LEU LEU D . n 
D 1 377 GLY 377 366 366 GLY GLY D . n 
D 1 378 TYR 378 367 367 TYR TYR D . n 
D 1 379 PHE 379 368 368 PHE PHE D . n 
D 1 380 TYR 380 369 369 TYR TYR D . n 
D 1 381 GLU 381 370 370 GLU GLU D . n 
D 1 382 SER 382 371 371 SER SER D . n 
D 1 383 ILE 383 372 372 ILE ILE D . n 
D 1 384 PHE 384 373 373 PHE PHE D . n 
D 1 385 THR 385 374 374 THR THR D . n 
D 1 386 LEU 386 375 375 LEU LEU D . n 
D 1 387 TYR 387 376 376 TYR TYR D . n 
D 1 388 ASN 388 377 377 ASN ASN D . n 
D 1 389 GLU 389 378 378 GLU GLU D . n 
D 1 390 ASN 390 379 379 ASN ASN D . n 
D 1 391 LYS 391 380 380 LYS LYS D . n 
D 1 392 ASP 392 381 381 ASP ASP D . n 
D 1 393 CYS 393 382 382 CYS CYS D . n 
D 1 394 VAL 394 383 383 VAL VAL D . n 
D 1 395 ASP 395 384 384 ASP ASP D . n 
D 1 396 THR 396 385 385 THR THR D . n 
D 1 397 ILE 397 386 386 ILE ILE D . n 
D 1 398 TYR 398 387 387 TYR TYR D . n 
D 1 399 TRP 399 388 388 TRP TRP D . n 
D 1 400 GLY 400 389 389 GLY GLY D . n 
D 1 401 LEU 401 390 390 LEU LEU D . n 
D 1 402 GLU 402 391 391 GLU GLU D . n 
D 1 403 GLY 403 392 392 GLY GLY D . n 
D 1 404 GLY 404 393 393 GLY GLY D . n 
D 1 405 TYR 405 394 394 TYR TYR D . n 
D 1 406 ASP 406 395 395 ASP ASP D . n 
D 1 407 ARG 407 396 396 ARG ARG D . n 
D 1 408 THR 408 397 397 THR THR D . n 
D 1 409 MET 409 398 398 MET MET D . n 
D 1 410 TYR 410 399 399 TYR TYR D . n 
D 1 411 GLU 411 400 400 GLU GLU D . n 
D 1 412 ARG 412 401 401 ARG ARG D . n 
D 1 413 GLU 413 402 402 GLU GLU D . n 
D 1 414 LEU 414 403 403 LEU LEU D . n 
D 1 415 LYS 415 404 404 LYS LYS D . n 
D 1 416 ILE 416 405 405 ILE ILE D . n 
D 1 417 LEU 417 406 406 LEU LEU D . n 
D 1 418 LEU 418 407 407 LEU LEU D . n 
D 1 419 GLN 419 408 408 GLN GLN D . n 
D 1 420 VAL 420 409 409 VAL VAL D . n 
D 1 421 ILE 421 410 410 ILE ILE D . n 
D 1 422 GLU 422 411 411 GLU GLU D . n 
D 1 423 LYS 423 412 412 LYS LYS D . n 
D 1 424 GLN 424 413 413 GLN GLN D . n 
D 1 425 LEU 425 414 414 LEU LEU D . n 
D 1 426 LEU 426 415 415 LEU LEU D . n 
D 1 427 PRO 427 416 416 PRO PRO D . n 
D 1 428 LYS 428 417 417 LYS LYS D . n 
D 1 429 ASP 429 418 ?   ?   ?   D . n 
D 1 430 SER 430 419 ?   ?   ?   D . n 
D 1 431 ASN 431 420 ?   ?   ?   D . n 
D 1 432 SER 432 421 ?   ?   ?   D . n 
D 1 433 HIS 433 422 ?   ?   ?   D . n 
D 1 434 SER 434 423 ?   ?   ?   D . n 
D 1 435 MET 435 424 ?   ?   ?   D . n 
D 1 436 SER 436 425 ?   ?   ?   D . n 
D 1 437 TYR 437 426 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        ZN 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   ZN 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 ZN  1 501 1  ZN  ZN  A . 
F 3 K   1 502 1  K   K   A . 
G 2 ZN  1 501 2  ZN  ZN  B . 
H 2 ZN  1 501 3  ZN  ZN  C . 
I 3 K   1 502 2  K   K   C . 
J 2 ZN  1 501 4  ZN  ZN  D . 
K 4 HOH 1 601 1  HOH HOH A . 
K 4 HOH 2 602 26 HOH HOH A . 
K 4 HOH 3 603 5  HOH HOH A . 
K 4 HOH 4 604 24 HOH HOH A . 
L 4 HOH 1 601 3  HOH HOH B . 
L 4 HOH 2 602 10 HOH HOH B . 
L 4 HOH 3 603 4  HOH HOH B . 
L 4 HOH 4 604 13 HOH HOH B . 
M 4 HOH 1 601 18 HOH HOH C . 
M 4 HOH 2 602 23 HOH HOH C . 
M 4 HOH 3 603 7  HOH HOH C . 
M 4 HOH 4 604 22 HOH HOH C . 
N 4 HOH 1 601 2  HOH HOH D . 
N 4 HOH 2 602 8  HOH HOH D . 
N 4 HOH 3 603 17 HOH HOH D . 
N 4 HOH 4 604 9  HOH HOH D . 
N 4 HOH 5 605 16 HOH HOH D . 
N 4 HOH 6 606 25 HOH HOH D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 C ASP 418 ? CG  ? C ASP 429 CG  
2 1 Y 1 C ASP 418 ? OD1 ? C ASP 429 OD1 
3 1 Y 1 C ASP 418 ? OD2 ? C ASP 429 OD2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0425                               1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? 'VERSION Jan 10, 2022  BUILT=20220820' 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? 'VERSION Jan 10, 2022  BUILT=20220820' 3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? v3.60.0                                4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GL0 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     109.121 
_cell.length_a_esd                 ? 
_cell.length_b                     109.121 
_cell.length_b_esd                 ? 
_cell.length_c                     400.511 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        32 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GL0 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                91 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 41 2 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GL0 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.98 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          58.79 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;0.1M calcium acetate
0.1M Na-HEPES pH 7.5,
18% (w/v) PEG8000
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-06-24 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.976300 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.976300 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   'P13 (MX1)' 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, EMBL c/o DESY' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9GL0 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.70 
_reflns.d_resolution_low                               45.96 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     66768 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     -3.0 
_reflns.percent_possible_obs                           98.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                24.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.38 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.161 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                0.158 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.70 
_reflns_shell.d_res_low                                     2.89 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.59 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             9462 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.673 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          87.3 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9GL0 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.7 
_refine.ls_d_res_low                             45.96 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     63975 
_refine.ls_number_reflns_R_free                  3279 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    94.56 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2441 
_refine.ls_R_factor_R_free                       0.316 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2403 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        12663 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         6 
_refine_hist.number_atoms_solvent             18 
_refine_hist.number_atoms_total               12687 
_refine_hist.d_res_high                       2.7 
_refine_hist.d_res_low                        45.96 
# 
_refine_ls_shell.R_factor_R_free                  0.6736 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.622 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.d_res_high                       2.70 
_refine_ls_shell.d_res_low                        2.74 
_refine_ls_shell.number_reflns_R_free             45 
_refine_ls_shell.number_reflns_R_work             ? 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                914 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.pdbx_total_number_of_bins_used   ? 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.percent_reflns_obs               33 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
# 
_struct.entry_id                     9GL0 
_struct.title                        'Crystal Structure of Acetylpolyamine aminohydrolase (ApaH) from Legionella pneumophila' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GL0 
_struct_keywords.text            'Deacetylase, Deacylase, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 2 ? 
H N N 2 ? 
I N N 3 ? 
J N N 2 ? 
K N N 4 ? 
L N N 4 ? 
M N N 4 ? 
N N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A2S6EWV0_LEGPN 
_struct_ref.pdbx_db_accession          A0A2S6EWV0 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MDMAKDKGFFKKAKMEKNKRLVTPYSEECAIQIPSEIDNEQMQRMPAGGEEDQYLRIKHMSALIKKYGDLPVITTQETRL
PYYWLDLFAAIDEGDTPKAHALFHLLPQDDIILRALRAVHSEDYLYQLIKYCIQAKHFGFKQLNADLVVTPKTFEILIRD
CATTLFNPAKAHFSFGLPSHHAYTQMGSGFCLINKTAMLMKQAELSSAQPPKFVIIGTDVNRDNGLCDILRHSFSHLSIC
HIDVFDSRVYPQQDFAYINNEFNSEGVDIGKNIHVWHHNNLNYYAVDLSLTSRKSVGVHPALLFALEQLKESIREAKAKG
QKIALYLPTGWDSHEDETAYCGKFVNGRMMGKTAAHQFRFNDGDLGYFYESIFTLYNENKDCVDTIYWGLEGGYDRTMYE
RELKILLQVIEKQLLPKDSNSHSMSY
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9GL0 A 12 ? 437 ? A0A2S6EWV0 1 ? 426 ? 1 426 
2 1 9GL0 B 12 ? 437 ? A0A2S6EWV0 1 ? 426 ? 1 426 
3 1 9GL0 C 12 ? 437 ? A0A2S6EWV0 1 ? 426 ? 1 426 
4 1 9GL0 D 12 ? 437 ? A0A2S6EWV0 1 ? 426 ? 1 426 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9GL0 MET A 1  ? UNP A0A2S6EWV0 ? ? 'initiating methionine' -10 1  
1 9GL0 ALA A 2  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -9  2  
1 9GL0 HIS A 3  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -8  3  
1 9GL0 HIS A 4  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -7  4  
1 9GL0 HIS A 5  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -6  5  
1 9GL0 HIS A 6  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -5  6  
1 9GL0 HIS A 7  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -4  7  
1 9GL0 HIS A 8  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -3  8  
1 9GL0 VAL A 9  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -2  9  
1 9GL0 GLY A 10 ? UNP A0A2S6EWV0 ? ? 'expression tag'        -1  10 
1 9GL0 THR A 11 ? UNP A0A2S6EWV0 ? ? 'expression tag'        0   11 
2 9GL0 MET B 1  ? UNP A0A2S6EWV0 ? ? 'initiating methionine' -10 12 
2 9GL0 ALA B 2  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -9  13 
2 9GL0 HIS B 3  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -8  14 
2 9GL0 HIS B 4  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -7  15 
2 9GL0 HIS B 5  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -6  16 
2 9GL0 HIS B 6  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -5  17 
2 9GL0 HIS B 7  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -4  18 
2 9GL0 HIS B 8  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -3  19 
2 9GL0 VAL B 9  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -2  20 
2 9GL0 GLY B 10 ? UNP A0A2S6EWV0 ? ? 'expression tag'        -1  21 
2 9GL0 THR B 11 ? UNP A0A2S6EWV0 ? ? 'expression tag'        0   22 
3 9GL0 MET C 1  ? UNP A0A2S6EWV0 ? ? 'initiating methionine' -10 23 
3 9GL0 ALA C 2  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -9  24 
3 9GL0 HIS C 3  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -8  25 
3 9GL0 HIS C 4  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -7  26 
3 9GL0 HIS C 5  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -6  27 
3 9GL0 HIS C 6  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -5  28 
3 9GL0 HIS C 7  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -4  29 
3 9GL0 HIS C 8  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -3  30 
3 9GL0 VAL C 9  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -2  31 
3 9GL0 GLY C 10 ? UNP A0A2S6EWV0 ? ? 'expression tag'        -1  32 
3 9GL0 THR C 11 ? UNP A0A2S6EWV0 ? ? 'expression tag'        0   33 
4 9GL0 MET D 1  ? UNP A0A2S6EWV0 ? ? 'initiating methionine' -10 34 
4 9GL0 ALA D 2  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -9  35 
4 9GL0 HIS D 3  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -8  36 
4 9GL0 HIS D 4  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -7  37 
4 9GL0 HIS D 5  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -6  38 
4 9GL0 HIS D 6  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -5  39 
4 9GL0 HIS D 7  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -4  40 
4 9GL0 HIS D 8  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -3  41 
4 9GL0 VAL D 9  ? UNP A0A2S6EWV0 ? ? 'expression tag'        -2  42 
4 9GL0 GLY D 10 ? UNP A0A2S6EWV0 ? ? 'expression tag'        -1  43 
4 9GL0 THR D 11 ? UNP A0A2S6EWV0 ? ? 'expression tag'        0   44 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
3 author_defined_assembly ? monomeric 1 
4 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,E,F,K 
2 1 B,G,L   
3 1 C,H,I,M 
4 1 D,J,N   
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 46  ? GLN A 52  ? SER A 35  GLN A 41  1 ? 7  
HELX_P HELX_P2  AA2 ASP A 63  ? TYR A 78  ? ASP A 52  TYR A 67  1 ? 16 
HELX_P HELX_P3  AA3 PRO A 92  ? GLY A 105 ? PRO A 81  GLY A 94  1 ? 14 
HELX_P HELX_P4  AA4 ASP A 106 ? LEU A 116 ? ASP A 95  LEU A 105 1 ? 11 
HELX_P HELX_P5  AA5 ASP A 121 ? HIS A 131 ? ASP A 110 HIS A 120 1 ? 11 
HELX_P HELX_P6  AA6 SER A 132 ? LYS A 147 ? SER A 121 LYS A 136 1 ? 16 
HELX_P HELX_P7  AA7 LYS A 163 ? PHE A 177 ? LYS A 152 PHE A 166 1 ? 15 
HELX_P HELX_P8  AA8 ASN A 205 ? SER A 218 ? ASN A 194 SER A 207 1 ? 14 
HELX_P HELX_P9  AA9 ASP A 234 ? PHE A 245 ? ASP A 223 PHE A 234 1 ? 12 
HELX_P HELX_P10 AB1 ASP A 265 ? ASN A 274 ? ASP A 254 ASN A 263 1 ? 10 
HELX_P HELX_P11 AB2 HIS A 310 ? GLY A 331 ? HIS A 299 GLY A 320 1 ? 22 
HELX_P HELX_P12 AB3 ALA A 350 ? LYS A 354 ? ALA A 339 LYS A 343 1 ? 5  
HELX_P HELX_P13 AB4 GLY A 362 ? ARG A 370 ? GLY A 351 ARG A 359 1 ? 9  
HELX_P HELX_P14 AB5 ASN A 372 ? ASN A 390 ? ASN A 361 ASN A 379 1 ? 19 
HELX_P HELX_P15 AB6 ASP A 406 ? LEU A 425 ? ASP A 395 LEU A 414 1 ? 20 
HELX_P HELX_P16 AB7 SER B 46  ? GLN B 52  ? SER B 35  GLN B 41  1 ? 7  
HELX_P HELX_P17 AB8 ASP B 63  ? TYR B 78  ? ASP B 52  TYR B 67  1 ? 16 
HELX_P HELX_P18 AB9 PRO B 92  ? GLY B 105 ? PRO B 81  GLY B 94  1 ? 14 
HELX_P HELX_P19 AC1 ASP B 106 ? LEU B 116 ? ASP B 95  LEU B 105 1 ? 11 
HELX_P HELX_P20 AC2 ASP B 121 ? HIS B 131 ? ASP B 110 HIS B 120 1 ? 11 
HELX_P HELX_P21 AC3 SER B 132 ? LYS B 147 ? SER B 121 LYS B 136 1 ? 16 
HELX_P HELX_P22 AC4 LYS B 163 ? PHE B 177 ? LYS B 152 PHE B 166 1 ? 15 
HELX_P HELX_P23 AC5 ASN B 205 ? SER B 217 ? ASN B 194 SER B 206 1 ? 13 
HELX_P HELX_P24 AC6 ASP B 234 ? PHE B 245 ? ASP B 223 PHE B 234 1 ? 12 
HELX_P HELX_P25 AC7 ASP B 265 ? ASN B 274 ? ASP B 254 ASN B 263 1 ? 10 
HELX_P HELX_P26 AC8 HIS B 310 ? ALA B 329 ? HIS B 299 ALA B 318 1 ? 20 
HELX_P HELX_P27 AC9 ALA B 350 ? LYS B 354 ? ALA B 339 LYS B 343 1 ? 5  
HELX_P HELX_P28 AD1 GLY B 362 ? ARG B 370 ? GLY B 351 ARG B 359 1 ? 9  
HELX_P HELX_P29 AD2 ASN B 372 ? ASN B 390 ? ASN B 361 ASN B 379 1 ? 19 
HELX_P HELX_P30 AD3 ASP B 406 ? LEU B 425 ? ASP B 395 LEU B 414 1 ? 20 
HELX_P HELX_P31 AD4 SER C 46  ? GLN C 52  ? SER C 35  GLN C 41  1 ? 7  
HELX_P HELX_P32 AD5 ASP C 63  ? TYR C 78  ? ASP C 52  TYR C 67  1 ? 16 
HELX_P HELX_P33 AD6 GLN C 87  ? THR C 89  ? GLN C 76  THR C 78  5 ? 3  
HELX_P HELX_P34 AD7 PRO C 92  ? GLU C 104 ? PRO C 81  GLU C 93  1 ? 13 
HELX_P HELX_P35 AD8 ASP C 106 ? HIS C 115 ? ASP C 95  HIS C 104 1 ? 10 
HELX_P HELX_P36 AD9 ASP C 121 ? HIS C 131 ? ASP C 110 HIS C 120 1 ? 11 
HELX_P HELX_P37 AE1 SER C 132 ? LYS C 147 ? SER C 121 LYS C 136 1 ? 16 
HELX_P HELX_P38 AE2 LYS C 163 ? ASN C 178 ? LYS C 152 ASN C 167 1 ? 16 
HELX_P HELX_P39 AE3 ASN C 205 ? LEU C 216 ? ASN C 194 LEU C 205 1 ? 12 
HELX_P HELX_P40 AE4 ASP C 234 ? PHE C 245 ? ASP C 223 PHE C 234 1 ? 12 
HELX_P HELX_P41 AE5 ASP C 265 ? ASN C 274 ? ASP C 254 ASN C 263 1 ? 10 
HELX_P HELX_P42 AE6 HIS C 310 ? LYS C 328 ? HIS C 299 LYS C 317 1 ? 19 
HELX_P HELX_P43 AE7 ALA C 350 ? LYS C 354 ? ALA C 339 LYS C 343 1 ? 5  
HELX_P HELX_P44 AE8 GLY C 362 ? ARG C 370 ? GLY C 351 ARG C 359 1 ? 9  
HELX_P HELX_P45 AE9 ASN C 372 ? ASN C 390 ? ASN C 361 ASN C 379 1 ? 19 
HELX_P HELX_P46 AF1 ASP C 406 ? LEU C 425 ? ASP C 395 LEU C 414 1 ? 20 
HELX_P HELX_P47 AF2 SER D 46  ? GLU D 51  ? SER D 35  GLU D 40  1 ? 6  
HELX_P HELX_P48 AF3 ASP D 63  ? TYR D 78  ? ASP D 52  TYR D 67  1 ? 16 
HELX_P HELX_P49 AF4 PRO D 92  ? GLY D 105 ? PRO D 81  GLY D 94  1 ? 14 
HELX_P HELX_P50 AF5 ASP D 106 ? HIS D 115 ? ASP D 95  HIS D 104 1 ? 10 
HELX_P HELX_P51 AF6 ASP D 121 ? HIS D 131 ? ASP D 110 HIS D 120 1 ? 11 
HELX_P HELX_P52 AF7 SER D 132 ? ALA D 146 ? SER D 121 ALA D 135 1 ? 15 
HELX_P HELX_P53 AF8 LYS D 163 ? PHE D 177 ? LYS D 152 PHE D 166 1 ? 15 
HELX_P HELX_P54 AF9 ASN D 205 ? SER D 217 ? ASN D 194 SER D 206 1 ? 13 
HELX_P HELX_P55 AG1 ASP D 234 ? PHE D 245 ? ASP D 223 PHE D 234 1 ? 12 
HELX_P HELX_P56 AG2 ASP D 265 ? PHE D 273 ? ASP D 254 PHE D 262 1 ? 9  
HELX_P HELX_P57 AG3 HIS D 310 ? LYS D 330 ? HIS D 299 LYS D 319 1 ? 21 
HELX_P HELX_P58 AG4 ALA D 350 ? LYS D 354 ? ALA D 339 LYS D 343 1 ? 5  
HELX_P HELX_P59 AG5 GLY D 362 ? ARG D 370 ? GLY D 351 ARG D 359 1 ? 9  
HELX_P HELX_P60 AG6 ASN D 372 ? ASN D 390 ? ASN D 361 ASN D 379 1 ? 19 
HELX_P HELX_P61 AG7 ASP D 406 ? LEU D 426 ? ASP D 395 LEU D 415 1 ? 21 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A GLY 228 O   ? ? ? 1_555 F K   . K  ? ? A GLY 217 A K   502 1_555 ? ? ? ? ? ? ? 2.820 ? ? 
metalc2  metalc ? ? A ASP 230 OD1 ? ? ? 1_555 E ZN  . ZN ? ? A ASP 219 A ZN  501 1_555 ? ? ? ? ? ? ? 1.978 ? ? 
metalc3  metalc ? ? A ASP 230 OD2 ? ? ? 1_555 E ZN  . ZN ? ? A ASP 219 A ZN  501 1_555 ? ? ? ? ? ? ? 2.338 ? ? 
metalc4  metalc ? ? A ASP 230 O   ? ? ? 1_555 F K   . K  ? ? A ASP 219 A K   502 1_555 ? ? ? ? ? ? ? 2.639 ? ? 
metalc5  metalc ? ? A ASN 232 OD1 ? ? ? 1_555 E ZN  . ZN ? ? A ASN 221 A ZN  501 1_555 ? ? ? ? ? ? ? 2.012 ? ? 
metalc6  metalc ? ? A ASN 232 O   ? ? ? 1_555 F K   . K  ? ? A ASN 221 A K   502 1_555 ? ? ? ? ? ? ? 3.058 ? ? 
metalc7  metalc ? ? A ASP 234 OD1 ? ? ? 1_555 F K   . K  ? ? A ASP 223 A K   502 1_555 ? ? ? ? ? ? ? 2.913 ? ? 
metalc8  metalc ? ? A ASP 254 OD1 ? ? ? 1_555 F K   . K  ? ? A ASP 243 A K   502 1_555 ? ? ? ? ? ? ? 2.765 ? ? 
metalc9  metalc ? ? A VAL 255 O   ? ? ? 1_555 F K   . K  ? ? A VAL 244 A K   502 1_555 ? ? ? ? ? ? ? 2.709 ? ? 
metalc10 metalc ? ? A ASP 343 OD2 ? ? ? 1_555 E ZN  . ZN ? ? A ASP 332 A ZN  501 1_555 ? ? ? ? ? ? ? 2.385 ? ? 
metalc11 metalc ? ? B ASP 230 OD1 ? ? ? 1_555 G ZN  . ZN ? ? B ASP 219 B ZN  501 1_555 ? ? ? ? ? ? ? 2.329 ? ? 
metalc12 metalc ? ? B ASP 230 OD2 ? ? ? 1_555 G ZN  . ZN ? ? B ASP 219 B ZN  501 1_555 ? ? ? ? ? ? ? 2.410 ? ? 
metalc13 metalc ? ? B ASN 232 OD1 ? ? ? 1_555 G ZN  . ZN ? ? B ASN 221 B ZN  501 1_555 ? ? ? ? ? ? ? 2.344 ? ? 
metalc14 metalc ? ? B ASP 343 OD2 ? ? ? 1_555 G ZN  . ZN ? ? B ASP 332 B ZN  501 1_555 ? ? ? ? ? ? ? 1.989 ? ? 
metalc15 metalc ? ? C GLY 228 O   ? ? ? 1_555 I K   . K  ? ? C GLY 217 C K   502 1_555 ? ? ? ? ? ? ? 2.929 ? ? 
metalc16 metalc ? ? C ASP 230 OD1 ? ? ? 1_555 H ZN  . ZN ? ? C ASP 219 C ZN  501 1_555 ? ? ? ? ? ? ? 2.295 ? ? 
metalc17 metalc ? ? C ASP 230 OD2 ? ? ? 1_555 H ZN  . ZN ? ? C ASP 219 C ZN  501 1_555 ? ? ? ? ? ? ? 2.637 ? ? 
metalc18 metalc ? ? C ASP 230 O   ? ? ? 1_555 I K   . K  ? ? C ASP 219 C K   502 1_555 ? ? ? ? ? ? ? 3.077 ? ? 
metalc19 metalc ? ? C ASN 232 OD1 ? ? ? 1_555 H ZN  . ZN ? ? C ASN 221 C ZN  501 1_555 ? ? ? ? ? ? ? 2.310 ? ? 
metalc20 metalc ? ? C ASN 232 O   ? ? ? 1_555 I K   . K  ? ? C ASN 221 C K   502 1_555 ? ? ? ? ? ? ? 3.094 ? ? 
metalc21 metalc ? ? C ASP 234 OD1 ? ? ? 1_555 I K   . K  ? ? C ASP 223 C K   502 1_555 ? ? ? ? ? ? ? 2.554 ? ? 
metalc22 metalc ? ? C ASP 234 OD2 ? ? ? 1_555 I K   . K  ? ? C ASP 223 C K   502 1_555 ? ? ? ? ? ? ? 3.495 ? ? 
metalc23 metalc ? ? C VAL 255 O   ? ? ? 1_555 I K   . K  ? ? C VAL 244 C K   502 1_555 ? ? ? ? ? ? ? 2.995 ? ? 
metalc24 metalc ? ? C ASP 343 OD2 ? ? ? 1_555 H ZN  . ZN ? ? C ASP 332 C ZN  501 1_555 ? ? ? ? ? ? ? 2.518 ? ? 
metalc25 metalc ? ? H ZN  .   ZN  ? ? ? 1_555 M HOH . O  ? ? C ZN  501 C HOH 601 1_555 ? ? ? ? ? ? ? 2.094 ? ? 
metalc26 metalc ? ? H ZN  .   ZN  ? ? ? 1_555 M HOH . O  ? ? C ZN  501 C HOH 604 1_555 ? ? ? ? ? ? ? 2.508 ? ? 
metalc27 metalc ? ? D ASP 230 OD1 ? ? ? 1_555 J ZN  . ZN ? ? D ASP 219 D ZN  501 1_555 ? ? ? ? ? ? ? 2.426 ? ? 
metalc28 metalc ? ? D ASP 230 OD2 ? ? ? 1_555 J ZN  . ZN ? ? D ASP 219 D ZN  501 1_555 ? ? ? ? ? ? ? 2.545 ? ? 
metalc29 metalc ? ? D ASN 232 OD1 ? ? ? 1_555 J ZN  . ZN ? ? D ASN 221 D ZN  501 1_555 ? ? ? ? ? ? ? 2.022 ? ? 
metalc30 metalc ? ? D ASP 343 OD2 ? ? ? 1_555 J ZN  . ZN ? ? D ASP 332 D ZN  501 1_555 ? ? ? ? ? ? ? 2.022 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O   ? A GLY 228 ? A GLY 217 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 O   ? A ASP 230 ? A ASP 219 ? 1_555 94.3  ? 
2  O   ? A GLY 228 ? A GLY 217 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 O   ? A ASN 232 ? A ASN 221 ? 1_555 161.2 ? 
3  O   ? A ASP 230 ? A ASP 219 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 O   ? A ASN 232 ? A ASN 221 ? 1_555 69.1  ? 
4  O   ? A GLY 228 ? A GLY 217 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 OD1 ? A ASP 234 ? A ASP 223 ? 1_555 102.5 ? 
5  O   ? A ASP 230 ? A ASP 219 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 OD1 ? A ASP 234 ? A ASP 223 ? 1_555 133.6 ? 
6  O   ? A ASN 232 ? A ASN 221 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 OD1 ? A ASP 234 ? A ASP 223 ? 1_555 84.2  ? 
7  O   ? A GLY 228 ? A GLY 217 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 OD1 ? A ASP 254 ? A ASP 243 ? 1_555 85.8  ? 
8  O   ? A ASP 230 ? A ASP 219 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 OD1 ? A ASP 254 ? A ASP 243 ? 1_555 148.3 ? 
9  O   ? A ASN 232 ? A ASN 221 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 OD1 ? A ASP 254 ? A ASP 243 ? 1_555 113.0 ? 
10 OD1 ? A ASP 234 ? A ASP 223 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 OD1 ? A ASP 254 ? A ASP 243 ? 1_555 76.6  ? 
11 O   ? A GLY 228 ? A GLY 217 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 O   ? A VAL 255 ? A VAL 244 ? 1_555 71.5  ? 
12 O   ? A ASP 230 ? A ASP 219 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 O   ? A VAL 255 ? A VAL 244 ? 1_555 65.8  ? 
13 O   ? A ASN 232 ? A ASN 221 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 O   ? A VAL 255 ? A VAL 244 ? 1_555 107.4 ? 
14 OD1 ? A ASP 234 ? A ASP 223 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 O   ? A VAL 255 ? A VAL 244 ? 1_555 160.6 ? 
15 OD1 ? A ASP 254 ? A ASP 243 ? 1_555 K  ? F K  . ? A K  502 ? 1_555 O   ? A VAL 255 ? A VAL 244 ? 1_555 84.4  ? 
16 OD1 ? A ASP 230 ? A ASP 219 ? 1_555 ZN ? E ZN . ? A ZN 501 ? 1_555 OD2 ? A ASP 230 ? A ASP 219 ? 1_555 60.8  ? 
17 OD1 ? A ASP 230 ? A ASP 219 ? 1_555 ZN ? E ZN . ? A ZN 501 ? 1_555 OD1 ? A ASN 232 ? A ASN 221 ? 1_555 91.7  ? 
18 OD2 ? A ASP 230 ? A ASP 219 ? 1_555 ZN ? E ZN . ? A ZN 501 ? 1_555 OD1 ? A ASN 232 ? A ASN 221 ? 1_555 152.5 ? 
19 OD1 ? A ASP 230 ? A ASP 219 ? 1_555 ZN ? E ZN . ? A ZN 501 ? 1_555 OD2 ? A ASP 343 ? A ASP 332 ? 1_555 109.6 ? 
20 OD2 ? A ASP 230 ? A ASP 219 ? 1_555 ZN ? E ZN . ? A ZN 501 ? 1_555 OD2 ? A ASP 343 ? A ASP 332 ? 1_555 111.0 ? 
21 OD1 ? A ASN 232 ? A ASN 221 ? 1_555 ZN ? E ZN . ? A ZN 501 ? 1_555 OD2 ? A ASP 343 ? A ASP 332 ? 1_555 76.7  ? 
22 OD1 ? B ASP 230 ? B ASP 219 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OD2 ? B ASP 230 ? B ASP 219 ? 1_555 55.7  ? 
23 OD1 ? B ASP 230 ? B ASP 219 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OD1 ? B ASN 232 ? B ASN 221 ? 1_555 78.2  ? 
24 OD2 ? B ASP 230 ? B ASP 219 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OD1 ? B ASN 232 ? B ASN 221 ? 1_555 133.1 ? 
25 OD1 ? B ASP 230 ? B ASP 219 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OD2 ? B ASP 343 ? B ASP 332 ? 1_555 96.4  ? 
26 OD2 ? B ASP 230 ? B ASP 219 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OD2 ? B ASP 343 ? B ASP 332 ? 1_555 81.8  ? 
27 OD1 ? B ASN 232 ? B ASN 221 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OD2 ? B ASP 343 ? B ASP 332 ? 1_555 96.6  ? 
28 O   ? C GLY 228 ? C GLY 217 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 O   ? C ASP 230 ? C ASP 219 ? 1_555 100.2 ? 
29 O   ? C GLY 228 ? C GLY 217 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 O   ? C ASN 232 ? C ASN 221 ? 1_555 164.3 ? 
30 O   ? C ASP 230 ? C ASP 219 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 O   ? C ASN 232 ? C ASN 221 ? 1_555 68.0  ? 
31 O   ? C GLY 228 ? C GLY 217 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 OD1 ? C ASP 234 ? C ASP 223 ? 1_555 97.4  ? 
32 O   ? C ASP 230 ? C ASP 219 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 OD1 ? C ASP 234 ? C ASP 223 ? 1_555 157.4 ? 
33 O   ? C ASN 232 ? C ASN 221 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 OD1 ? C ASP 234 ? C ASP 223 ? 1_555 91.9  ? 
34 O   ? C GLY 228 ? C GLY 217 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 OD2 ? C ASP 234 ? C ASP 223 ? 1_555 90.3  ? 
35 O   ? C ASP 230 ? C ASP 219 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 OD2 ? C ASP 234 ? C ASP 223 ? 1_555 153.8 ? 
36 O   ? C ASN 232 ? C ASN 221 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 OD2 ? C ASP 234 ? C ASP 223 ? 1_555 104.7 ? 
37 OD1 ? C ASP 234 ? C ASP 223 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 OD2 ? C ASP 234 ? C ASP 223 ? 1_555 38.7  ? 
38 O   ? C GLY 228 ? C GLY 217 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 O   ? C VAL 255 ? C VAL 244 ? 1_555 73.6  ? 
39 O   ? C ASP 230 ? C ASP 219 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 O   ? C VAL 255 ? C VAL 244 ? 1_555 56.5  ? 
40 O   ? C ASN 232 ? C ASN 221 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 O   ? C VAL 255 ? C VAL 244 ? 1_555 90.9  ? 
41 OD1 ? C ASP 234 ? C ASP 223 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 O   ? C VAL 255 ? C VAL 244 ? 1_555 116.5 ? 
42 OD2 ? C ASP 234 ? C ASP 223 ? 1_555 K  ? I K  . ? C K  502 ? 1_555 O   ? C VAL 255 ? C VAL 244 ? 1_555 149.4 ? 
43 OD1 ? C ASP 230 ? C ASP 219 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 OD2 ? C ASP 230 ? C ASP 219 ? 1_555 52.7  ? 
44 OD1 ? C ASP 230 ? C ASP 219 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 OD1 ? C ASN 232 ? C ASN 221 ? 1_555 72.1  ? 
45 OD2 ? C ASP 230 ? C ASP 219 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 OD1 ? C ASN 232 ? C ASN 221 ? 1_555 124.5 ? 
46 OD1 ? C ASP 230 ? C ASP 219 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 OD2 ? C ASP 343 ? C ASP 332 ? 1_555 81.1  ? 
47 OD2 ? C ASP 230 ? C ASP 219 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 OD2 ? C ASP 343 ? C ASP 332 ? 1_555 95.8  ? 
48 OD1 ? C ASN 232 ? C ASN 221 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 OD2 ? C ASP 343 ? C ASP 332 ? 1_555 68.0  ? 
49 OD1 ? C ASP 230 ? C ASP 219 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 O   ? M HOH .   ? C HOH 601 ? 1_555 135.2 ? 
50 OD2 ? C ASP 230 ? C ASP 219 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 O   ? M HOH .   ? C HOH 601 ? 1_555 171.3 ? 
51 OD1 ? C ASN 232 ? C ASN 221 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 O   ? M HOH .   ? C HOH 601 ? 1_555 63.1  ? 
52 OD2 ? C ASP 343 ? C ASP 332 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 O   ? M HOH .   ? C HOH 601 ? 1_555 83.1  ? 
53 OD1 ? C ASP 230 ? C ASP 219 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 O   ? M HOH .   ? C HOH 604 ? 1_555 131.5 ? 
54 OD2 ? C ASP 230 ? C ASP 219 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 O   ? M HOH .   ? C HOH 604 ? 1_555 127.5 ? 
55 OD1 ? C ASN 232 ? C ASN 221 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 O   ? M HOH .   ? C HOH 604 ? 1_555 91.6  ? 
56 OD2 ? C ASP 343 ? C ASP 332 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 O   ? M HOH .   ? C HOH 604 ? 1_555 135.3 ? 
57 O   ? M HOH .   ? C HOH 601 ? 1_555 ZN ? H ZN . ? C ZN 501 ? 1_555 O   ? M HOH .   ? C HOH 604 ? 1_555 52.3  ? 
58 OD1 ? D ASP 230 ? D ASP 219 ? 1_555 ZN ? J ZN . ? D ZN 501 ? 1_555 OD2 ? D ASP 230 ? D ASP 219 ? 1_555 52.8  ? 
59 OD1 ? D ASP 230 ? D ASP 219 ? 1_555 ZN ? J ZN . ? D ZN 501 ? 1_555 OD1 ? D ASN 232 ? D ASN 221 ? 1_555 77.5  ? 
60 OD2 ? D ASP 230 ? D ASP 219 ? 1_555 ZN ? J ZN . ? D ZN 501 ? 1_555 OD1 ? D ASN 232 ? D ASN 221 ? 1_555 129.8 ? 
61 OD1 ? D ASP 230 ? D ASP 219 ? 1_555 ZN ? J ZN . ? D ZN 501 ? 1_555 OD2 ? D ASP 343 ? D ASP 332 ? 1_555 98.4  ? 
62 OD2 ? D ASP 230 ? D ASP 219 ? 1_555 ZN ? J ZN . ? D ZN 501 ? 1_555 OD2 ? D ASP 343 ? D ASP 332 ? 1_555 83.2  ? 
63 OD1 ? D ASN 232 ? D ASN 221 ? 1_555 ZN ? J ZN . ? D ZN 501 ? 1_555 OD2 ? D ASP 343 ? D ASP 332 ? 1_555 99.6  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TYR 261 A . ? TYR 250 A PRO 262 A ? PRO 251 A 1 -1.11  
2 TYR 261 B . ? TYR 250 B PRO 262 B ? PRO 251 B 1 -6.42  
3 TYR 261 C . ? TYR 250 C PRO 262 C ? PRO 251 C 1 -11.02 
4 TYR 261 D . ? TYR 250 D PRO 262 D ? PRO 251 D 1 -3.50  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 10 ? 
AA2 ? 2  ? 
AA3 ? 2  ? 
AA4 ? 10 ? 
AA5 ? 2  ? 
AA6 ? 2  ? 
AA7 ? 10 ? 
AA8 ? 2  ? 
AA9 ? 2  ? 
AB1 ? 10 ? 
AB2 ? 2  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? parallel      
AA1 2 3  ? parallel      
AA1 3 4  ? parallel      
AA1 4 5  ? parallel      
AA1 5 6  ? parallel      
AA1 6 7  ? parallel      
AA1 7 8  ? parallel      
AA1 8 9  ? anti-parallel 
AA1 9 10 ? anti-parallel 
AA2 1 2  ? anti-parallel 
AA3 1 2  ? anti-parallel 
AA4 1 2  ? parallel      
AA4 2 3  ? parallel      
AA4 3 4  ? parallel      
AA4 4 5  ? parallel      
AA4 5 6  ? parallel      
AA4 6 7  ? parallel      
AA4 7 8  ? parallel      
AA4 8 9  ? anti-parallel 
AA4 9 10 ? anti-parallel 
AA5 1 2  ? anti-parallel 
AA6 1 2  ? anti-parallel 
AA7 1 2  ? parallel      
AA7 2 3  ? parallel      
AA7 3 4  ? parallel      
AA7 4 5  ? parallel      
AA7 5 6  ? parallel      
AA7 6 7  ? parallel      
AA7 7 8  ? parallel      
AA7 8 9  ? anti-parallel 
AA7 9 10 ? anti-parallel 
AA8 1 2  ? anti-parallel 
AA9 1 2  ? anti-parallel 
AB1 1 2  ? parallel      
AB1 2 3  ? parallel      
AB1 3 4  ? parallel      
AB1 4 5  ? parallel      
AB1 5 6  ? parallel      
AB1 6 7  ? parallel      
AB1 7 8  ? parallel      
AB1 8 9  ? anti-parallel 
AB1 9 10 ? anti-parallel 
AB2 1 2  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  VAL A 83  ? THR A 85  ? VAL A 72  THR A 74  
AA1 2  CYS A 40  ? ILE A 44  ? CYS A 29  ILE A 33  
AA1 3  ALA A 182 ? SER A 185 ? ALA A 171 SER A 174 
AA1 4  VAL A 394 ? LEU A 401 ? VAL A 383 LEU A 390 
AA1 5  ILE A 334 ? THR A 340 ? ILE A 323 THR A 329 
AA1 6  LYS A 223 ? GLY A 228 ? LYS A 212 GLY A 217 
AA1 7  ILE A 250 ? PHE A 256 ? ILE A 239 PHE A 245 
AA1 8  LEU A 292 ? ASP A 298 ? LEU A 281 ASP A 287 
AA1 9  ILE A 284 ? HIS A 289 ? ILE A 273 HIS A 278 
AA1 10 VAL A 278 ? ASP A 279 ? VAL A 267 ASP A 268 
AA2 1  LYS A 152 ? ASN A 155 ? LYS A 141 ASN A 144 
AA2 2  LEU A 158 ? VAL A 160 ? LEU A 147 VAL A 149 
AA3 1  PHE A 355 ? VAL A 356 ? PHE A 344 VAL A 345 
AA3 2  ARG A 359 ? MET A 360 ? ARG A 348 MET A 349 
AA4 1  VAL B 83  ? THR B 85  ? VAL B 72  THR B 74  
AA4 2  ALA B 41  ? ILE B 44  ? ALA B 30  ILE B 33  
AA4 3  ALA B 182 ? SER B 185 ? ALA B 171 SER B 174 
AA4 4  VAL B 394 ? LEU B 401 ? VAL B 383 LEU B 390 
AA4 5  ILE B 334 ? THR B 340 ? ILE B 323 THR B 329 
AA4 6  LYS B 223 ? GLY B 228 ? LYS B 212 GLY B 217 
AA4 7  ILE B 250 ? PHE B 256 ? ILE B 239 PHE B 245 
AA4 8  LEU B 292 ? ASP B 298 ? LEU B 281 ASP B 287 
AA4 9  ILE B 284 ? HIS B 289 ? ILE B 273 HIS B 278 
AA4 10 VAL B 278 ? ASP B 279 ? VAL B 267 ASP B 268 
AA5 1  LYS B 152 ? ASN B 155 ? LYS B 141 ASN B 144 
AA5 2  LEU B 158 ? VAL B 160 ? LEU B 147 VAL B 149 
AA6 1  PHE B 355 ? VAL B 356 ? PHE B 344 VAL B 345 
AA6 2  ARG B 359 ? MET B 360 ? ARG B 348 MET B 349 
AA7 1  VAL C 83  ? THR C 85  ? VAL C 72  THR C 74  
AA7 2  CYS C 40  ? ILE C 44  ? CYS C 29  ILE C 33  
AA7 3  ALA C 182 ? SER C 185 ? ALA C 171 SER C 174 
AA7 4  VAL C 394 ? LEU C 401 ? VAL C 383 LEU C 390 
AA7 5  ILE C 334 ? THR C 340 ? ILE C 323 THR C 329 
AA7 6  LYS C 223 ? GLY C 228 ? LYS C 212 GLY C 217 
AA7 7  ILE C 250 ? PHE C 256 ? ILE C 239 PHE C 245 
AA7 8  LEU C 292 ? ASP C 298 ? LEU C 281 ASP C 287 
AA7 9  ILE C 284 ? HIS C 289 ? ILE C 273 HIS C 278 
AA7 10 VAL C 278 ? GLY C 281 ? VAL C 267 GLY C 270 
AA8 1  LYS C 152 ? GLN C 153 ? LYS C 141 GLN C 142 
AA8 2  VAL C 159 ? VAL C 160 ? VAL C 148 VAL C 149 
AA9 1  PHE C 355 ? VAL C 356 ? PHE C 344 VAL C 345 
AA9 2  ARG C 359 ? MET C 360 ? ARG C 348 MET C 349 
AB1 1  VAL D 83  ? ILE D 84  ? VAL D 72  ILE D 73  
AB1 2  CYS D 40  ? GLN D 43  ? CYS D 29  GLN D 32  
AB1 3  ALA D 182 ? SER D 185 ? ALA D 171 SER D 174 
AB1 4  VAL D 394 ? LEU D 401 ? VAL D 383 LEU D 390 
AB1 5  ILE D 334 ? THR D 340 ? ILE D 323 THR D 329 
AB1 6  LYS D 223 ? GLY D 228 ? LYS D 212 GLY D 217 
AB1 7  ILE D 250 ? PHE D 256 ? ILE D 239 PHE D 245 
AB1 8  LEU D 292 ? ASP D 298 ? LEU D 281 ASP D 287 
AB1 9  ILE D 284 ? HIS D 289 ? ILE D 273 HIS D 278 
AB1 10 VAL D 278 ? GLY D 281 ? VAL D 267 GLY D 270 
AB2 1  PHE D 355 ? VAL D 356 ? PHE D 344 VAL D 345 
AB2 2  ARG D 359 ? MET D 360 ? ARG D 348 MET D 349 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  O ILE A 84  ? O ILE A 73  N ILE A 42  ? N ILE A 31  
AA1 2 3  N GLN A 43  ? N GLN A 32  O PHE A 184 ? O PHE A 173 
AA1 3 4  N HIS A 183 ? N HIS A 172 O TRP A 399 ? O TRP A 388 
AA1 4 5  O ASP A 395 ? O ASP A 384 N ILE A 334 ? N ILE A 323 
AA1 5 6  O TYR A 337 ? O TYR A 326 N ILE A 227 ? N ILE A 216 
AA1 6 7  N ILE A 226 ? N ILE A 215 O CYS A 251 ? O CYS A 240 
AA1 7 8  N ASP A 254 ? N ASP A 243 O TYR A 295 ? O TYR A 284 
AA1 8 9  O TYR A 294 ? O TYR A 283 N TRP A 287 ? N TRP A 276 
AA1 9 10 O VAL A 286 ? O VAL A 275 N VAL A 278 ? N VAL A 267 
AA2 1 2  N LEU A 154 ? N LEU A 143 O LEU A 158 ? O LEU A 147 
AA3 1 2  N VAL A 356 ? N VAL A 345 O ARG A 359 ? O ARG A 348 
AA4 1 2  O ILE B 84  ? O ILE B 73  N ILE B 42  ? N ILE B 31  
AA4 2 3  N GLN B 43  ? N GLN B 32  O PHE B 184 ? O PHE B 173 
AA4 3 4  N HIS B 183 ? N HIS B 172 O TRP B 399 ? O TRP B 388 
AA4 4 5  O TYR B 398 ? O TYR B 387 N LEU B 338 ? N LEU B 327 
AA4 5 6  O TYR B 337 ? O TYR B 326 N ILE B 227 ? N ILE B 216 
AA4 6 7  N ILE B 226 ? N ILE B 215 O CYS B 251 ? O CYS B 240 
AA4 7 8  N ILE B 250 ? N ILE B 239 O ASN B 293 ? O ASN B 282 
AA4 8 9  O ALA B 296 ? O ALA B 285 N HIS B 285 ? N HIS B 274 
AA4 9 10 O VAL B 286 ? O VAL B 275 N VAL B 278 ? N VAL B 267 
AA5 1 2  N LEU B 154 ? N LEU B 143 O LEU B 158 ? O LEU B 147 
AA6 1 2  N VAL B 356 ? N VAL B 345 O ARG B 359 ? O ARG B 348 
AA7 1 2  O ILE C 84  ? O ILE C 73  N ILE C 42  ? N ILE C 31  
AA7 2 3  N GLN C 43  ? N GLN C 32  O PHE C 184 ? O PHE C 173 
AA7 3 4  N HIS C 183 ? N HIS C 172 O TRP C 399 ? O TRP C 388 
AA7 4 5  O ASP C 395 ? O ASP C 384 N ILE C 334 ? N ILE C 323 
AA7 5 6  O ALA C 335 ? O ALA C 324 N LYS C 223 ? N LYS C 212 
AA7 6 7  N PHE C 224 ? N PHE C 213 O CYS C 251 ? O CYS C 240 
AA7 7 8  N ILE C 250 ? N ILE C 239 O ASN C 293 ? O ASN C 282 
AA7 8 9  O LEU C 292 ? O LEU C 281 N HIS C 289 ? N HIS C 278 
AA7 9 10 O ILE C 284 ? O ILE C 273 N GLY C 281 ? N GLY C 270 
AA8 1 2  N LYS C 152 ? N LYS C 141 O VAL C 160 ? O VAL C 149 
AA9 1 2  N VAL C 356 ? N VAL C 345 O ARG C 359 ? O ARG C 348 
AB1 1 2  O ILE D 84  ? O ILE D 73  N ILE D 42  ? N ILE D 31  
AB1 2 3  N GLN D 43  ? N GLN D 32  O PHE D 184 ? O PHE D 173 
AB1 3 4  N HIS D 183 ? N HIS D 172 O ILE D 397 ? O ILE D 386 
AB1 4 5  O GLY D 400 ? O GLY D 389 N LEU D 338 ? N LEU D 327 
AB1 5 6  O TYR D 337 ? O TYR D 326 N VAL D 225 ? N VAL D 214 
AB1 6 7  N ILE D 226 ? N ILE D 215 O ILE D 253 ? O ILE D 242 
AB1 7 8  N HIS D 252 ? N HIS D 241 O TYR D 295 ? O TYR D 284 
AB1 8 9  O ALA D 296 ? O ALA D 285 N HIS D 285 ? N HIS D 274 
AB1 9 10 O ILE D 284 ? O ILE D 273 N GLY D 281 ? N GLY D 270 
AB2 1 2  N VAL D 356 ? N VAL D 345 O ARG D 359 ? O ARG D 348 
# 
_pdbx_entry_details.entry_id                   9GL0 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   C HOH 601 ? ? O   C HOH 604 ? ? 2.06 
2 1 O   A GLN 202 ? ? OG  A SER 206 ? ? 2.08 
3 1 NH1 D ARG 293 ? ? O   D HIS 356 ? ? 2.14 
4 1 OE1 C GLU 311 ? ? NH1 C ARG 314 ? ? 2.17 
5 1 OE2 A GLU 370 ? ? NZ  A LYS 412 ? ? 2.18 
6 1 O   C VAL 119 ? ? OG1 C THR 184 ? ? 2.19 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CA 
_pdbx_validate_rmsd_bond.auth_asym_id_1            B 
_pdbx_validate_rmsd_bond.auth_comp_id_1            ASP 
_pdbx_validate_rmsd_bond.auth_seq_id_1             69 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            CB 
_pdbx_validate_rmsd_bond.auth_asym_id_2            B 
_pdbx_validate_rmsd_bond.auth_comp_id_2            ASP 
_pdbx_validate_rmsd_bond.auth_seq_id_2             69 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.687 
_pdbx_validate_rmsd_bond.bond_target_value         1.535 
_pdbx_validate_rmsd_bond.bond_deviation            0.152 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.022 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1   1 GLN A 41  ? ? -80.81  38.12   
2   1 ARG A 44  ? ? 69.99   -4.44   
3   1 TYR A 67  ? ? -59.93  90.07   
4   1 THR A 75  ? ? -66.24  0.64    
5   1 HIS A 137 ? ? -69.33  -71.61  
6   1 LEU A 143 ? ? -82.19  -73.56  
7   1 ALA A 162 ? ? -47.99  -70.83  
8   1 SER A 179 ? ? -144.11 -29.67  
9   1 GLN A 185 ? ? -140.42 -19.48  
10  1 PHE A 190 ? ? 67.12   -0.74   
11  1 ASN A 194 ? ? -107.23 77.93   
12  1 ASP A 223 ? ? -68.28  54.66   
13  1 LEU A 226 ? ? -36.65  -34.44  
14  1 SER A 247 ? ? -59.27  9.89    
15  1 VAL A 249 ? ? -97.30  -158.13 
16  1 GLN A 252 ? ? 56.91   15.25   
17  1 ASP A 254 ? ? -117.91 -165.22 
18  1 ASN A 263 ? ? 21.59   49.65   
19  1 LYS A 271 ? ? -64.10  62.54   
20  1 ASN A 279 ? ? 58.29   -102.65 
21  1 SER A 295 ? ? 54.08   -90.58  
22  1 SER A 295 ? ? 49.73   -90.58  
23  1 ASN A 346 ? ? 24.38   73.60   
24  1 ARG A 359 ? ? -110.76 -169.19 
25  1 ASN A 379 ? ? -140.25 47.33   
26  1 ASP A 384 ? ? -99.23  -84.21  
27  1 GLU A 391 ? ? -106.89 -97.72  
28  1 SER B 35  ? ? -59.91  174.57  
29  1 GLN B 41  ? ? -72.28  22.85   
30  1 ARG B 44  ? ? 67.77   -9.87   
31  1 ASP B 69  ? ? -119.09 75.25   
32  1 PRO B 71  ? ? -65.86  91.00   
33  1 THR B 75  ? ? -68.64  3.43    
34  1 ASP B 95  ? ? -69.75  93.36   
35  1 ASP B 110 ? ? -31.54  129.89  
36  1 LYS B 141 ? ? -160.79 106.30  
37  1 LEU B 143 ? ? -99.68  -65.87  
38  1 PHE B 166 ? ? -99.36  36.98   
39  1 PHE B 166 ? ? -99.36  37.65   
40  1 SER B 179 ? ? -132.64 -31.37  
41  1 GLN B 185 ? ? -151.05 16.53   
42  1 ALA B 208 ? ? -68.77  -77.99  
43  1 HIS B 232 ? ? -80.39  -72.48  
44  1 SER B 235 ? ? -56.29  -4.50   
45  1 ASN B 263 ? ? 32.77   54.65   
46  1 LYS B 271 ? ? -64.56  52.50   
47  1 ASN B 272 ? ? 52.60   75.96   
48  1 ILE B 273 ? ? -162.78 111.59  
49  1 ASN B 279 ? ? 58.41   -98.28  
50  1 SER B 295 ? ? 40.30   -64.83  
51  1 ASP B 332 ? ? -42.99  -17.09  
52  1 SER B 333 ? ? -79.78  23.98   
53  1 ASN B 379 ? ? -117.32 64.22   
54  1 GLU B 391 ? ? -82.74  -110.74 
55  1 LYS B 417 ? ? 53.63   -105.00 
56  1 CYS C 29  ? ? -174.48 140.62  
57  1 ARG C 44  ? ? 61.38   -13.29  
58  1 TYR C 67  ? ? -57.75  101.53  
59  1 PRO C 71  ? ? -68.81  80.47   
60  1 ALA C 101 ? ? -93.25  51.16   
61  1 LEU C 102 ? ? -163.38 -38.44  
62  1 PRO C 107 ? ? -38.82  131.35  
63  1 LEU C 143 ? ? -110.64 -102.42 
64  1 ASN C 144 ? ? -74.69  -167.49 
65  1 SER C 179 ? ? -154.22 -42.48  
66  1 HIS C 180 ? ? -59.32  -1.89   
67  1 PHE C 190 ? ? 72.99   -14.74  
68  1 LEU C 205 ? ? -87.75  33.49   
69  1 ASP C 219 ? ? -33.51  143.74  
70  1 PRO C 251 ? ? -96.64  58.61   
71  1 GLN C 252 ? ? 34.10   26.45   
72  1 LYS C 271 ? ? 29.65   32.61   
73  1 HIS C 278 ? ? -160.29 106.17  
74  1 ASN C 279 ? ? 54.99   -101.54 
75  1 LEU C 288 ? ? -56.29  -8.48   
76  1 LYS C 294 ? ? -103.90 74.37   
77  1 SER C 295 ? ? 59.20   -155.00 
78  1 ASN C 379 ? ? -72.31  36.80   
79  1 LEU C 390 ? ? -57.80  104.17  
80  1 GLU C 391 ? ? -92.09  -95.63  
81  1 ARG D 44  ? ? 84.44   -20.95  
82  1 TYR D 67  ? ? -49.03  93.27   
83  1 THR D 74  ? ? -95.30  -151.96 
84  1 GLU D 77  ? ? -161.62 -2.28   
85  1 ARG D 79  ? ? 58.04   105.01  
86  1 HIS D 104 ? ? -68.90  0.44    
87  1 GLU D 122 ? ? -32.17  -21.01  
88  1 LEU D 143 ? ? -73.34  -121.10 
89  1 ASN D 144 ? ? -68.09  -163.48 
90  1 SER D 179 ? ? -146.55 -45.20  
91  1 ALA D 208 ? ? -54.80  -91.27  
92  1 HIS D 232 ? ? -81.33  -75.32  
93  1 GLN D 252 ? ? 62.81   -3.08   
94  1 ASN D 263 ? ? -0.49   61.02   
95  1 LYS D 271 ? ? 25.18   43.29   
96  1 HIS D 278 ? ? -166.85 104.58  
97  1 ASN D 279 ? ? 61.08   -129.80 
98  1 SER D 292 ? ? -74.55  -133.70 
99  1 SER D 295 ? ? 56.60   -147.28 
100 1 GLU D 311 ? ? -61.00  -79.83  
101 1 SER D 312 ? ? -36.44  -19.68  
102 1 ASN D 346 ? ? 4.11    68.79   
103 1 ASN D 379 ? ? -100.01 49.15   
104 1 GLU D 391 ? ? -107.45 -102.53 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -10 ? A MET 1   
2   1 Y 1 A ALA -9  ? A ALA 2   
3   1 Y 1 A HIS -8  ? A HIS 3   
4   1 Y 1 A HIS -7  ? A HIS 4   
5   1 Y 1 A HIS -6  ? A HIS 5   
6   1 Y 1 A HIS -5  ? A HIS 6   
7   1 Y 1 A HIS -4  ? A HIS 7   
8   1 Y 1 A HIS -3  ? A HIS 8   
9   1 Y 1 A VAL -2  ? A VAL 9   
10  1 Y 1 A GLY -1  ? A GLY 10  
11  1 Y 1 A THR 0   ? A THR 11  
12  1 Y 1 A MET 1   ? A MET 12  
13  1 Y 1 A ASP 2   ? A ASP 13  
14  1 Y 1 A MET 3   ? A MET 14  
15  1 Y 1 A ALA 4   ? A ALA 15  
16  1 Y 1 A LYS 5   ? A LYS 16  
17  1 Y 1 A ASP 6   ? A ASP 17  
18  1 Y 1 A LYS 7   ? A LYS 18  
19  1 Y 1 A GLY 8   ? A GLY 19  
20  1 Y 1 A PHE 9   ? A PHE 20  
21  1 Y 1 A PHE 10  ? A PHE 21  
22  1 Y 1 A LYS 11  ? A LYS 22  
23  1 Y 1 A LYS 12  ? A LYS 23  
24  1 Y 1 A ALA 13  ? A ALA 24  
25  1 Y 1 A LYS 14  ? A LYS 25  
26  1 Y 1 A MET 15  ? A MET 26  
27  1 Y 1 A GLU 16  ? A GLU 27  
28  1 Y 1 A LYS 17  ? A LYS 28  
29  1 Y 1 A ASN 18  ? A ASN 29  
30  1 Y 1 A LYS 19  ? A LYS 30  
31  1 Y 1 A ARG 20  ? A ARG 31  
32  1 Y 1 A LEU 21  ? A LEU 32  
33  1 Y 1 A VAL 22  ? A VAL 33  
34  1 Y 1 A THR 23  ? A THR 34  
35  1 Y 1 A PRO 24  ? A PRO 35  
36  1 Y 1 A TYR 25  ? A TYR 36  
37  1 Y 1 A SER 419 ? A SER 430 
38  1 Y 1 A ASN 420 ? A ASN 431 
39  1 Y 1 A SER 421 ? A SER 432 
40  1 Y 1 A HIS 422 ? A HIS 433 
41  1 Y 1 A SER 423 ? A SER 434 
42  1 Y 1 A MET 424 ? A MET 435 
43  1 Y 1 A SER 425 ? A SER 436 
44  1 Y 1 A TYR 426 ? A TYR 437 
45  1 Y 1 B MET -10 ? B MET 1   
46  1 Y 1 B ALA -9  ? B ALA 2   
47  1 Y 1 B HIS -8  ? B HIS 3   
48  1 Y 1 B HIS -7  ? B HIS 4   
49  1 Y 1 B HIS -6  ? B HIS 5   
50  1 Y 1 B HIS -5  ? B HIS 6   
51  1 Y 1 B HIS -4  ? B HIS 7   
52  1 Y 1 B HIS -3  ? B HIS 8   
53  1 Y 1 B VAL -2  ? B VAL 9   
54  1 Y 1 B GLY -1  ? B GLY 10  
55  1 Y 1 B THR 0   ? B THR 11  
56  1 Y 1 B MET 1   ? B MET 12  
57  1 Y 1 B ASP 2   ? B ASP 13  
58  1 Y 1 B MET 3   ? B MET 14  
59  1 Y 1 B ALA 4   ? B ALA 15  
60  1 Y 1 B LYS 5   ? B LYS 16  
61  1 Y 1 B ASP 6   ? B ASP 17  
62  1 Y 1 B LYS 7   ? B LYS 18  
63  1 Y 1 B GLY 8   ? B GLY 19  
64  1 Y 1 B PHE 9   ? B PHE 20  
65  1 Y 1 B PHE 10  ? B PHE 21  
66  1 Y 1 B LYS 11  ? B LYS 22  
67  1 Y 1 B LYS 12  ? B LYS 23  
68  1 Y 1 B ALA 13  ? B ALA 24  
69  1 Y 1 B LYS 14  ? B LYS 25  
70  1 Y 1 B MET 15  ? B MET 26  
71  1 Y 1 B GLU 16  ? B GLU 27  
72  1 Y 1 B LYS 17  ? B LYS 28  
73  1 Y 1 B ASN 18  ? B ASN 29  
74  1 Y 1 B LYS 19  ? B LYS 30  
75  1 Y 1 B ARG 20  ? B ARG 31  
76  1 Y 1 B LEU 21  ? B LEU 32  
77  1 Y 1 B VAL 22  ? B VAL 33  
78  1 Y 1 B THR 23  ? B THR 34  
79  1 Y 1 B PRO 24  ? B PRO 35  
80  1 Y 1 B TYR 25  ? B TYR 36  
81  1 Y 1 B SER 26  ? B SER 37  
82  1 Y 1 B SER 419 ? B SER 430 
83  1 Y 1 B ASN 420 ? B ASN 431 
84  1 Y 1 B SER 421 ? B SER 432 
85  1 Y 1 B HIS 422 ? B HIS 433 
86  1 Y 1 B SER 423 ? B SER 434 
87  1 Y 1 B MET 424 ? B MET 435 
88  1 Y 1 B SER 425 ? B SER 436 
89  1 Y 1 B TYR 426 ? B TYR 437 
90  1 Y 1 C MET -10 ? C MET 1   
91  1 Y 1 C ALA -9  ? C ALA 2   
92  1 Y 1 C HIS -8  ? C HIS 3   
93  1 Y 1 C HIS -7  ? C HIS 4   
94  1 Y 1 C HIS -6  ? C HIS 5   
95  1 Y 1 C HIS -5  ? C HIS 6   
96  1 Y 1 C HIS -4  ? C HIS 7   
97  1 Y 1 C HIS -3  ? C HIS 8   
98  1 Y 1 C VAL -2  ? C VAL 9   
99  1 Y 1 C GLY -1  ? C GLY 10  
100 1 Y 1 C THR 0   ? C THR 11  
101 1 Y 1 C MET 1   ? C MET 12  
102 1 Y 1 C ASP 2   ? C ASP 13  
103 1 Y 1 C MET 3   ? C MET 14  
104 1 Y 1 C ALA 4   ? C ALA 15  
105 1 Y 1 C LYS 5   ? C LYS 16  
106 1 Y 1 C ASP 6   ? C ASP 17  
107 1 Y 1 C LYS 7   ? C LYS 18  
108 1 Y 1 C GLY 8   ? C GLY 19  
109 1 Y 1 C PHE 9   ? C PHE 20  
110 1 Y 1 C PHE 10  ? C PHE 21  
111 1 Y 1 C LYS 11  ? C LYS 22  
112 1 Y 1 C LYS 12  ? C LYS 23  
113 1 Y 1 C ALA 13  ? C ALA 24  
114 1 Y 1 C LYS 14  ? C LYS 25  
115 1 Y 1 C MET 15  ? C MET 26  
116 1 Y 1 C GLU 16  ? C GLU 27  
117 1 Y 1 C LYS 17  ? C LYS 28  
118 1 Y 1 C ASN 18  ? C ASN 29  
119 1 Y 1 C LYS 19  ? C LYS 30  
120 1 Y 1 C ARG 20  ? C ARG 31  
121 1 Y 1 C LEU 21  ? C LEU 32  
122 1 Y 1 C VAL 22  ? C VAL 33  
123 1 Y 1 C THR 23  ? C THR 34  
124 1 Y 1 C PRO 24  ? C PRO 35  
125 1 Y 1 C TYR 25  ? C TYR 36  
126 1 Y 1 C SER 26  ? C SER 37  
127 1 Y 1 C SER 419 ? C SER 430 
128 1 Y 1 C ASN 420 ? C ASN 431 
129 1 Y 1 C SER 421 ? C SER 432 
130 1 Y 1 C HIS 422 ? C HIS 433 
131 1 Y 1 C SER 423 ? C SER 434 
132 1 Y 1 C MET 424 ? C MET 435 
133 1 Y 1 C SER 425 ? C SER 436 
134 1 Y 1 C TYR 426 ? C TYR 437 
135 1 Y 1 D MET -10 ? D MET 1   
136 1 Y 1 D ALA -9  ? D ALA 2   
137 1 Y 1 D HIS -8  ? D HIS 3   
138 1 Y 1 D HIS -7  ? D HIS 4   
139 1 Y 1 D HIS -6  ? D HIS 5   
140 1 Y 1 D HIS -5  ? D HIS 6   
141 1 Y 1 D HIS -4  ? D HIS 7   
142 1 Y 1 D HIS -3  ? D HIS 8   
143 1 Y 1 D VAL -2  ? D VAL 9   
144 1 Y 1 D GLY -1  ? D GLY 10  
145 1 Y 1 D THR 0   ? D THR 11  
146 1 Y 1 D MET 1   ? D MET 12  
147 1 Y 1 D ASP 2   ? D ASP 13  
148 1 Y 1 D MET 3   ? D MET 14  
149 1 Y 1 D ALA 4   ? D ALA 15  
150 1 Y 1 D LYS 5   ? D LYS 16  
151 1 Y 1 D ASP 6   ? D ASP 17  
152 1 Y 1 D LYS 7   ? D LYS 18  
153 1 Y 1 D GLY 8   ? D GLY 19  
154 1 Y 1 D PHE 9   ? D PHE 20  
155 1 Y 1 D PHE 10  ? D PHE 21  
156 1 Y 1 D LYS 11  ? D LYS 22  
157 1 Y 1 D LYS 12  ? D LYS 23  
158 1 Y 1 D ALA 13  ? D ALA 24  
159 1 Y 1 D LYS 14  ? D LYS 25  
160 1 Y 1 D MET 15  ? D MET 26  
161 1 Y 1 D GLU 16  ? D GLU 27  
162 1 Y 1 D LYS 17  ? D LYS 28  
163 1 Y 1 D ASN 18  ? D ASN 29  
164 1 Y 1 D LYS 19  ? D LYS 30  
165 1 Y 1 D ARG 20  ? D ARG 31  
166 1 Y 1 D LEU 21  ? D LEU 32  
167 1 Y 1 D VAL 22  ? D VAL 33  
168 1 Y 1 D THR 23  ? D THR 34  
169 1 Y 1 D PRO 24  ? D PRO 35  
170 1 Y 1 D TYR 25  ? D TYR 36  
171 1 Y 1 D SER 26  ? D SER 37  
172 1 Y 1 D ASP 418 ? D ASP 429 
173 1 Y 1 D SER 419 ? D SER 430 
174 1 Y 1 D ASN 420 ? D ASN 431 
175 1 Y 1 D SER 421 ? D SER 432 
176 1 Y 1 D HIS 422 ? D HIS 433 
177 1 Y 1 D SER 423 ? D SER 434 
178 1 Y 1 D MET 424 ? D MET 435 
179 1 Y 1 D SER 425 ? D SER 436 
180 1 Y 1 D TYR 426 ? D TYR 437 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
HOH O    O  N N 158 
HOH H1   H  N N 159 
HOH H2   H  N N 160 
ILE N    N  N N 161 
ILE CA   C  N S 162 
ILE C    C  N N 163 
ILE O    O  N N 164 
ILE CB   C  N S 165 
ILE CG1  C  N N 166 
ILE CG2  C  N N 167 
ILE CD1  C  N N 168 
ILE OXT  O  N N 169 
ILE H    H  N N 170 
ILE H2   H  N N 171 
ILE HA   H  N N 172 
ILE HB   H  N N 173 
ILE HG12 H  N N 174 
ILE HG13 H  N N 175 
ILE HG21 H  N N 176 
ILE HG22 H  N N 177 
ILE HG23 H  N N 178 
ILE HD11 H  N N 179 
ILE HD12 H  N N 180 
ILE HD13 H  N N 181 
ILE HXT  H  N N 182 
K   K    K  N N 183 
LEU N    N  N N 184 
LEU CA   C  N S 185 
LEU C    C  N N 186 
LEU O    O  N N 187 
LEU CB   C  N N 188 
LEU CG   C  N N 189 
LEU CD1  C  N N 190 
LEU CD2  C  N N 191 
LEU OXT  O  N N 192 
LEU H    H  N N 193 
LEU H2   H  N N 194 
LEU HA   H  N N 195 
LEU HB2  H  N N 196 
LEU HB3  H  N N 197 
LEU HG   H  N N 198 
LEU HD11 H  N N 199 
LEU HD12 H  N N 200 
LEU HD13 H  N N 201 
LEU HD21 H  N N 202 
LEU HD22 H  N N 203 
LEU HD23 H  N N 204 
LEU HXT  H  N N 205 
LYS N    N  N N 206 
LYS CA   C  N S 207 
LYS C    C  N N 208 
LYS O    O  N N 209 
LYS CB   C  N N 210 
LYS CG   C  N N 211 
LYS CD   C  N N 212 
LYS CE   C  N N 213 
LYS NZ   N  N N 214 
LYS OXT  O  N N 215 
LYS H    H  N N 216 
LYS H2   H  N N 217 
LYS HA   H  N N 218 
LYS HB2  H  N N 219 
LYS HB3  H  N N 220 
LYS HG2  H  N N 221 
LYS HG3  H  N N 222 
LYS HD2  H  N N 223 
LYS HD3  H  N N 224 
LYS HE2  H  N N 225 
LYS HE3  H  N N 226 
LYS HZ1  H  N N 227 
LYS HZ2  H  N N 228 
LYS HZ3  H  N N 229 
LYS HXT  H  N N 230 
MET N    N  N N 231 
MET CA   C  N S 232 
MET C    C  N N 233 
MET O    O  N N 234 
MET CB   C  N N 235 
MET CG   C  N N 236 
MET SD   S  N N 237 
MET CE   C  N N 238 
MET OXT  O  N N 239 
MET H    H  N N 240 
MET H2   H  N N 241 
MET HA   H  N N 242 
MET HB2  H  N N 243 
MET HB3  H  N N 244 
MET HG2  H  N N 245 
MET HG3  H  N N 246 
MET HE1  H  N N 247 
MET HE2  H  N N 248 
MET HE3  H  N N 249 
MET HXT  H  N N 250 
PHE N    N  N N 251 
PHE CA   C  N S 252 
PHE C    C  N N 253 
PHE O    O  N N 254 
PHE CB   C  N N 255 
PHE CG   C  Y N 256 
PHE CD1  C  Y N 257 
PHE CD2  C  Y N 258 
PHE CE1  C  Y N 259 
PHE CE2  C  Y N 260 
PHE CZ   C  Y N 261 
PHE OXT  O  N N 262 
PHE H    H  N N 263 
PHE H2   H  N N 264 
PHE HA   H  N N 265 
PHE HB2  H  N N 266 
PHE HB3  H  N N 267 
PHE HD1  H  N N 268 
PHE HD2  H  N N 269 
PHE HE1  H  N N 270 
PHE HE2  H  N N 271 
PHE HZ   H  N N 272 
PHE HXT  H  N N 273 
PRO N    N  N N 274 
PRO CA   C  N S 275 
PRO C    C  N N 276 
PRO O    O  N N 277 
PRO CB   C  N N 278 
PRO CG   C  N N 279 
PRO CD   C  N N 280 
PRO OXT  O  N N 281 
PRO H    H  N N 282 
PRO HA   H  N N 283 
PRO HB2  H  N N 284 
PRO HB3  H  N N 285 
PRO HG2  H  N N 286 
PRO HG3  H  N N 287 
PRO HD2  H  N N 288 
PRO HD3  H  N N 289 
PRO HXT  H  N N 290 
SER N    N  N N 291 
SER CA   C  N S 292 
SER C    C  N N 293 
SER O    O  N N 294 
SER CB   C  N N 295 
SER OG   O  N N 296 
SER OXT  O  N N 297 
SER H    H  N N 298 
SER H2   H  N N 299 
SER HA   H  N N 300 
SER HB2  H  N N 301 
SER HB3  H  N N 302 
SER HG   H  N N 303 
SER HXT  H  N N 304 
THR N    N  N N 305 
THR CA   C  N S 306 
THR C    C  N N 307 
THR O    O  N N 308 
THR CB   C  N R 309 
THR OG1  O  N N 310 
THR CG2  C  N N 311 
THR OXT  O  N N 312 
THR H    H  N N 313 
THR H2   H  N N 314 
THR HA   H  N N 315 
THR HB   H  N N 316 
THR HG1  H  N N 317 
THR HG21 H  N N 318 
THR HG22 H  N N 319 
THR HG23 H  N N 320 
THR HXT  H  N N 321 
TRP N    N  N N 322 
TRP CA   C  N S 323 
TRP C    C  N N 324 
TRP O    O  N N 325 
TRP CB   C  N N 326 
TRP CG   C  Y N 327 
TRP CD1  C  Y N 328 
TRP CD2  C  Y N 329 
TRP NE1  N  Y N 330 
TRP CE2  C  Y N 331 
TRP CE3  C  Y N 332 
TRP CZ2  C  Y N 333 
TRP CZ3  C  Y N 334 
TRP CH2  C  Y N 335 
TRP OXT  O  N N 336 
TRP H    H  N N 337 
TRP H2   H  N N 338 
TRP HA   H  N N 339 
TRP HB2  H  N N 340 
TRP HB3  H  N N 341 
TRP HD1  H  N N 342 
TRP HE1  H  N N 343 
TRP HE3  H  N N 344 
TRP HZ2  H  N N 345 
TRP HZ3  H  N N 346 
TRP HH2  H  N N 347 
TRP HXT  H  N N 348 
TYR N    N  N N 349 
TYR CA   C  N S 350 
TYR C    C  N N 351 
TYR O    O  N N 352 
TYR CB   C  N N 353 
TYR CG   C  Y N 354 
TYR CD1  C  Y N 355 
TYR CD2  C  Y N 356 
TYR CE1  C  Y N 357 
TYR CE2  C  Y N 358 
TYR CZ   C  Y N 359 
TYR OH   O  N N 360 
TYR OXT  O  N N 361 
TYR H    H  N N 362 
TYR H2   H  N N 363 
TYR HA   H  N N 364 
TYR HB2  H  N N 365 
TYR HB3  H  N N 366 
TYR HD1  H  N N 367 
TYR HD2  H  N N 368 
TYR HE1  H  N N 369 
TYR HE2  H  N N 370 
TYR HH   H  N N 371 
TYR HXT  H  N N 372 
VAL N    N  N N 373 
VAL CA   C  N S 374 
VAL C    C  N N 375 
VAL O    O  N N 376 
VAL CB   C  N N 377 
VAL CG1  C  N N 378 
VAL CG2  C  N N 379 
VAL OXT  O  N N 380 
VAL H    H  N N 381 
VAL H2   H  N N 382 
VAL HA   H  N N 383 
VAL HB   H  N N 384 
VAL HG11 H  N N 385 
VAL HG12 H  N N 386 
VAL HG13 H  N N 387 
VAL HG21 H  N N 388 
VAL HG22 H  N N 389 
VAL HG23 H  N N 390 
VAL HXT  H  N N 391 
ZN  ZN   ZN N N 392 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'German Research Foundation (DFG)' Germany LA2984/6-1 1 
'German Research Foundation (DFG)' Germany LA2984/8-1 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   AF-A0A2S6EWV0-F1 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9GL0 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009164 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009164 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.002497 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
K  
N  
O  
S  
ZN 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.fract_x 
_atom_site.fract_y 
_atom_site.fract_z 
ATOM   1     N  N   . SER A 1 37  ? -15.821 -8.119  -1.314  1    122.96 ? 26  SER A N   1 -0.145 -0.074 -0.003 
ATOM   2     C  CA  . SER A 1 37  ? -17.28  -8.128  -1.284  1    133.06 ? 26  SER A CA  1 -0.158 -0.074 -0.003 
ATOM   3     C  C   . SER A 1 37  ? -17.839 -7.213  -2.37   1    143.86 ? 26  SER A C   1 -0.163 -0.066 -0.006 
ATOM   4     O  O   . SER A 1 37  ? -17.528 -6.015  -2.381  1    142.57 ? 26  SER A O   1 -0.161 -0.055 -0.006 
ATOM   5     C  CB  . SER A 1 37  ? -17.813 -7.68   0.09    1    143.44 ? 26  SER A CB  1 -0.163 -0.07  0.0    
ATOM   6     O  OG  . SER A 1 37  ? -17.322 -8.476  1.172   1    149.03 ? 26  SER A OG  1 -0.159 -0.078 0.003  
ATOM   7     N  N   . GLU A 1 38  ? -18.638 -7.786  -3.29   1    147.97 ? 27  GLU A N   1 -0.171 -0.071 -0.008 
ATOM   8     C  CA  . GLU A 1 38  ? -19.472 -7.034  -4.23   1    136.76 ? 27  GLU A CA  1 -0.178 -0.064 -0.011 
ATOM   9     C  C   . GLU A 1 38  ? -20.712 -6.423  -3.572  1    136.99 ? 27  GLU A C   1 -0.19  -0.059 -0.009 
ATOM   10    O  O   . GLU A 1 38  ? -21.414 -5.642  -4.227  1    132.89 ? 27  GLU A O   1 -0.196 -0.052 -0.011 
ATOM   11    C  CB  . GLU A 1 38  ? -19.936 -7.93   -5.397  1    131.36 ? 27  GLU A CB  1 -0.183 -0.073 -0.013 
ATOM   12    C  CG  . GLU A 1 38  ? -18.932 -8.131  -6.532  1    145.26 ? 27  GLU A CG  1 -0.173 -0.075 -0.016 
ATOM   13    C  CD  . GLU A 1 38  ? -19.573 -8.602  -7.857  1    145.25 ? 27  GLU A CD  1 -0.179 -0.079 -0.02  
ATOM   14    O  OE1 . GLU A 1 38  ? -20.783 -8.351  -8.086  1    144.65 ? 27  GLU A OE1 1 -0.19  -0.077 -0.02  
ATOM   15    O  OE2 . GLU A 1 38  ? -18.853 -9.222  -8.675  1    138    ? 27  GLU A OE2 1 -0.173 -0.085 -0.022 
ATOM   16    N  N   . GLU A 1 39  ? -21     -6.757  -2.3    1    130.23 ? 28  GLU A N   1 -0.192 -0.062 -0.006 
ATOM   17    C  CA  . GLU A 1 39  ? -22.257 -6.365  -1.665  1    125.69 ? 28  GLU A CA  1 -0.204 -0.058 -0.004 
ATOM   18    C  C   . GLU A 1 39  ? -22.229 -4.928  -1.143  1    120.8  ? 28  GLU A C   1 -0.204 -0.045 -0.003 
ATOM   19    O  O   . GLU A 1 39  ? -23.285 -4.312  -0.954  1    114.34 ? 28  GLU A O   1 -0.213 -0.04  -0.002 
ATOM   20    C  CB  . GLU A 1 39  ? -22.581 -7.34   -0.529  1    130.1  ? 28  GLU A CB  1 -0.207 -0.067 -0.001 
ATOM   21    C  CG  . GLU A 1 39  ? -24.07  -7.51   -0.223  1    131.47 ? 28  GLU A CG  1 -0.221 -0.069 -0.001 
ATOM   22    C  CD  . GLU A 1 39  ? -24.658 -6.344  0.571   1    137.05 ? 28  GLU A CD  1 -0.226 -0.058 0.001  
ATOM   23    O  OE1 . GLU A 1 39  ? -23.902 -5.704  1.341   1    134.4  ? 28  GLU A OE1 1 -0.219 -0.052 0.003  
ATOM   24    O  OE2 . GLU A 1 39  ? -25.873 -6.065  0.42    1    138    ? 28  GLU A OE2 1 -0.237 -0.056 0.001  
ATOM   25    N  N   . CYS A 1 40  ? -21.049 -4.374  -0.901  1    119.2  ? 29  CYS A N   1 -0.193 -0.04  -0.002 
ATOM   26    C  CA  . CYS A 1 40  ? -20.959 -2.988  -0.469  1    113.57 ? 29  CYS A CA  1 -0.192 -0.027 -0.001 
ATOM   27    C  C   . CYS A 1 40  ? -19.553 -2.49   -0.761  1    110.81 ? 29  CYS A C   1 -0.179 -0.023 -0.002 
ATOM   28    O  O   . CYS A 1 40  ? -18.591 -3.263  -0.719  1    115.09 ? 29  CYS A O   1 -0.17  -0.03  -0.002 
ATOM   29    C  CB  . CYS A 1 40  ? -21.301 -2.86   1.02    1    114.98 ? 29  CYS A CB  1 -0.195 -0.026 0.003  
ATOM   30    S  SG  . CYS A 1 40  ? -20.663 -1.392  1.881   1    112.52 ? 29  CYS A SG  1 -0.189 -0.013 0.005  
ATOM   31    N  N   . ALA A 1 41  ? -19.441 -1.199  -1.069  1    100.66 ? 30  ALA A N   1 -0.178 -0.011 -0.003 
ATOM   32    C  CA  . ALA A 1 41  ? -18.131 -0.602  -1.283  1    101.68 ? 30  ALA A CA  1 -0.166 -0.006 -0.003 
ATOM   33    C  C   . ALA A 1 41  ? -18.106 0.822   -0.736  1    99.98  ? 30  ALA A C   1 -0.166 0.008  -0.002 
ATOM   34    O  O   . ALA A 1 41  ? -19.146 1.431   -0.468  1    95.38  ? 30  ALA A O   1 -0.175 0.013  -0.001 
ATOM   35    C  CB  . ALA A 1 41  ? -17.741 -0.619  -2.762  1    98.39  ? 30  ALA A CB  1 -0.163 -0.006 -0.007 
ATOM   36    N  N   . ILE A 1 42  ? -16.89  1.337   -0.551  1    99.45  ? 31  ILE A N   1 -0.155 0.012  -0.001 
ATOM   37    C  CA  . ILE A 1 42  ? -16.652 2.7     -0.084  1    98.16  ? 31  ILE A CA  1 -0.153 0.025  -0.0   
ATOM   38    C  C   . ILE A 1 42  ? -15.582 3.318   -0.976  1    97.99  ? 31  ILE A C   1 -0.143 0.03   -0.002 
ATOM   39    O  O   . ILE A 1 42  ? -14.461 2.8     -1.059  1    99.61  ? 31  ILE A O   1 -0.133 0.026  -0.003 
ATOM   40    C  CB  . ILE A 1 42  ? -16.235 2.747   1.395   1    98.28  ? 31  ILE A CB  1 -0.149 0.025  0.003  
ATOM   41    C  CG1 . ILE A 1 42  ? -17.292 2.027   2.236   1    98.85  ? 31  ILE A CG1 1 -0.158 0.019  0.006  
ATOM   42    C  CG2 . ILE A 1 42  ? -16.039 4.197   1.859   1    89.4   ? 31  ILE A CG2 1 -0.147 0.038  0.005  
ATOM   43    C  CD1 . ILE A 1 42  ? -17.356 2.473   3.658   1    101.49 ? 31  ILE A CD1 1 -0.159 0.023  0.009  
ATOM   44    N  N   . GLN A 1 43  ? -15.919 4.422   -1.635  1    91.92  ? 32  GLN A N   1 -0.146 0.041  -0.004 
ATOM   45    C  CA  . GLN A 1 43  ? -15.13  4.936   -2.746  1    100.15 ? 32  GLN A CA  1 -0.139 0.045  -0.007 
ATOM   46    C  C   . GLN A 1 43  ? -14.431 6.225   -2.339  1    96.13  ? 32  GLN A C   1 -0.132 0.057  -0.006 
ATOM   47    O  O   . GLN A 1 43  ? -15.076 7.169   -1.865  1    90.37  ? 32  GLN A O   1 -0.138 0.066  -0.005 
ATOM   48    C  CB  . GLN A 1 43  ? -16.024 5.146   -3.98   1    97.4   ? 32  GLN A CB  1 -0.147 0.047  -0.01  
ATOM   49    C  CG  . GLN A 1 43  ? -15.495 6.07    -5.058  1    97.15  ? 32  GLN A CG  1 -0.142 0.056  -0.013 
ATOM   50    C  CD  . GLN A 1 43  ? -16.234 5.876   -6.407  1    107.66 ? 32  GLN A CD  1 -0.149 0.054  -0.016 
ATOM   51    O  OE1 . GLN A 1 43  ? -16.902 4.851   -6.631  1    103.87 ? 32  GLN A OE1 1 -0.155 0.044  -0.017 
ATOM   52    N  NE2 . GLN A 1 43  ? -16.092 6.851   -7.311  1    99.12  ? 32  GLN A NE2 1 -0.147 0.063  -0.018 
ATOM   53    N  N   . ILE A 1 44  ? -13.112 6.246   -2.509  1    91.18  ? 33  ILE A N   1 -0.12  0.057  -0.006 
ATOM   54    C  CA  . ILE A 1 44  ? -12.33  7.467   -2.341  1    93.79  ? 33  ILE A CA  1 -0.113 0.068  -0.006 
ATOM   55    C  C   . ILE A 1 44  ? -11.518 7.697   -3.606  1    96.8   ? 33  ILE A C   1 -0.106 0.071  -0.009 
ATOM   56    O  O   . ILE A 1 44  ? -11.21  6.75    -4.349  1    97.84  ? 33  ILE A O   1 -0.103 0.062  -0.011 
ATOM   57    C  CB  . ILE A 1 44  ? -11.392 7.38    -1.119  1    96.63  ? 33  ILE A CB  1 -0.104 0.068  -0.003 
ATOM   58    C  CG1 . ILE A 1 44  ? -10.627 6.061   -1.149  1    95.49  ? 33  ILE A CG1 1 -0.097 0.056  -0.003 
ATOM   59    C  CG2 . ILE A 1 44  ? -12.173 7.546   0.166   1    105.08 ? 33  ILE A CG2 1 -0.112 0.069  0.0    
ATOM   60    C  CD1 . ILE A 1 44  ? -9.253  6.163   -0.561  1    102.51 ? 33  ILE A CD1 1 -0.085 0.056  -0.001 
ATOM   61    N  N   . PRO A 1 45  ? -11.129 8.94    -3.868  1    91.98  ? 34  PRO A N   1 -0.102 0.082  -0.01  
ATOM   62    C  CA  . PRO A 1 45  ? -10.154 9.181   -4.933  1    94.84  ? 34  PRO A CA  1 -0.093 0.084  -0.012 
ATOM   63    C  C   . PRO A 1 45  ? -8.81   8.578   -4.578  1    96.91  ? 34  PRO A C   1 -0.081 0.079  -0.011 
ATOM   64    O  O   . PRO A 1 45  ? -8.452  8.433   -3.405  1    104.31 ? 34  PRO A O   1 -0.077 0.077  -0.009 
ATOM   65    C  CB  . PRO A 1 45  ? -10.067 10.71   -5.008  1    97.13  ? 34  PRO A CB  1 -0.092 0.098  -0.013 
ATOM   66    C  CG  . PRO A 1 45  ? -11.276 11.202  -4.268  1    102.17 ? 34  PRO A CG  1 -0.103 0.103  -0.011 
ATOM   67    C  CD  . PRO A 1 45  ? -11.566 10.188  -3.227  1    88.85  ? 34  PRO A CD  1 -0.106 0.093  -0.008 
ATOM   68    N  N   . SER A 1 46  ? -8.067  8.219   -5.616  1    103.82 ? 35  SER A N   1 -0.074 0.075  -0.014 
ATOM   69    C  CA  . SER A 1 46  ? -6.69   7.78    -5.469  1    105.51 ? 35  SER A CA  1 -0.061 0.071  -0.014 
ATOM   70    C  C   . SER A 1 46  ? -5.805  8.945   -5.028  1    98.96  ? 35  SER A C   1 -0.053 0.082  -0.013 
ATOM   71    O  O   . SER A 1 46  ? -6.252  10.089  -4.891  1    95.01  ? 35  SER A O   1 -0.057 0.092  -0.012 
ATOM   72    C  CB  . SER A 1 46  ? -6.19   7.203   -6.791  1    113.44 ? 35  SER A CB  1 -0.057 0.066  -0.017 
ATOM   73    O  OG  . SER A 1 46  ? -6.425  8.104   -7.867  1    105.32 ? 35  SER A OG  1 -0.059 0.074  -0.02  
ATOM   74    N  N   . GLU A 1 47  ? -4.516  8.659   -4.832  1    99.99  ? 36  GLU A N   1 -0.041 0.079  -0.012 
ATOM   75    C  CA  . GLU A 1 47  ? -3.582  9.72    -4.454  1    109.65 ? 36  GLU A CA  1 -0.033 0.089  -0.011 
ATOM   76    C  C   . GLU A 1 47  ? -3.567  10.835  -5.502  1    107.85 ? 36  GLU A C   1 -0.033 0.099  -0.014 
ATOM   77    O  O   . GLU A 1 47  ? -3.866  11.995  -5.187  1    98.7   ? 36  GLU A O   1 -0.035 0.11   -0.013 
ATOM   78    C  CB  . GLU A 1 47  ? -2.181  9.14    -4.226  1    114.36 ? 36  GLU A CB  1 -0.02  0.084  -0.011 
ATOM   79    C  CG  . GLU A 1 47  ? -1.315  9.941   -3.252  1    123.64 ? 36  GLU A CG  1 -0.012 0.091  -0.008 
ATOM   80    C  CD  . GLU A 1 47  ? -0.607  9.064   -2.202  1    145.43 ? 36  GLU A CD  1 -0.006 0.083  -0.005 
ATOM   81    O  OE1 . GLU A 1 47  ? -1.278  8.199   -1.592  1    149.38 ? 36  GLU A OE1 1 -0.012 0.075  -0.004 
ATOM   82    O  OE2 . GLU A 1 47  ? 0.618   9.245   -1.977  1    148.36 ? 36  GLU A OE2 1 0.006  0.085  -0.005 
ATOM   83    N  N   . ILE A 1 48  ? -3.268  10.485  -6.771  1    110.34 ? 37  ILE A N   1 -0.03  0.096  -0.017 
ATOM   84    C  CA  . ILE A 1 48  ? -3.206  11.482  -7.854  1    112.08 ? 37  ILE A CA  1 -0.029 0.105  -0.02  
ATOM   85    C  C   . ILE A 1 48  ? -4.534  12.217  -8.002  1    106.79 ? 37  ILE A C   1 -0.042 0.112  -0.02  
ATOM   86    O  O   . ILE A 1 48  ? -4.571  13.45   -8.117  1    98.73  ? 37  ILE A O   1 -0.042 0.123  -0.02  
ATOM   87    C  CB  . ILE A 1 48  ? -2.81   10.839  -9.201  1    116.06 ? 37  ILE A CB  1 -0.026 0.099  -0.023 
ATOM   88    C  CG1 . ILE A 1 48  ? -3.525  9.493   -9.424  1    120.71 ? 37  ILE A CG1 1 -0.032 0.087  -0.024 
ATOM   89    C  CG2 . ILE A 1 48  ? -1.307  10.803  -9.384  1    114.64 ? 37  ILE A CG2 1 -0.012 0.099  -0.023 
ATOM   90    C  CD1 . ILE A 1 48  ? -4.944  9.642   -10.105 1    113.75 ? 37  ILE A CD1 1 -0.045 0.088  -0.025 
ATOM   91    N  N   . ASP A 1 49  ? -5.643  11.472  -8.053  1    101.51 ? 38  ASP A N   1 -0.052 0.105  -0.02  
ATOM   92    C  CA  . ASP A 1 49  ? -6.936  12.114  -8.256  1    99.96  ? 38  ASP A CA  1 -0.064 0.111  -0.021 
ATOM   93    C  C   . ASP A 1 49  ? -7.227  13.149  -7.169  1    102.42 ? 38  ASP A C   1 -0.066 0.12   -0.018 
ATOM   94    O  O   . ASP A 1 49  ? -7.541  14.306  -7.478  1    101.38 ? 38  ASP A O   1 -0.069 0.131  -0.019 
ATOM   95    C  CB  . ASP A 1 49  ? -8.042  11.065  -8.356  1    101.35 ? 38  ASP A CB  1 -0.074 0.101  -0.021 
ATOM   96    C  CG  . ASP A 1 49  ? -8.188  10.491  -9.771  1    112    ? 38  ASP A CG  1 -0.075 0.096  -0.024 
ATOM   97    O  OD1 . ASP A 1 49  ? -7.575  11.029  -10.731 1    108.77 ? 38  ASP A OD1 1 -0.069 0.101  -0.027 
ATOM   98    O  OD2 . ASP A 1 49  ? -8.911  9.49    -9.931  1    115.75 ? 38  ASP A OD2 1 -0.082 0.087  -0.025 
ATOM   99    N  N   . ASN A 1 50  ? -7.114  12.761  -5.89   1    104.97 ? 39  ASN A N   1 -0.065 0.117  -0.015 
ATOM   100   C  CA  . ASN A 1 50  ? -7.265  13.725  -4.797  1    99.17  ? 39  ASN A CA  1 -0.067 0.126  -0.012 
ATOM   101   C  C   . ASN A 1 50  ? -6.269  14.878  -4.915  1    96.23  ? 39  ASN A C   1 -0.057 0.136  -0.012 
ATOM   102   O  O   . ASN A 1 50  ? -6.634  16.043  -4.715  1    96.27  ? 39  ASN A O   1 -0.061 0.147  -0.012 
ATOM   103   C  CB  . ASN A 1 50  ? -7.117  13.023  -3.451  1    99.12  ? 39  ASN A CB  1 -0.065 0.119  -0.009 
ATOM   104   C  CG  . ASN A 1 50  ? -7.097  13.994  -2.286  1    99.79  ? 39  ASN A CG  1 -0.065 0.128  -0.006 
ATOM   105   O  OD1 . ASN A 1 50  ? -6.308  13.853  -1.336  1    98.15  ? 39  ASN A OD1 1 -0.058 0.127  -0.003 
ATOM   106   N  ND2 . ASN A 1 50  ? -7.95   15.008  -2.365  1    99.56  ? 39  ASN A ND2 1 -0.073 0.138  -0.006 
ATOM   107   N  N   . GLU A 1 51  ? -5.006  14.581  -5.241  1    93.49  ? 40  GLU A N   1 -0.046 0.134  -0.013 
ATOM   108   C  CA  . GLU A 1 51  ? -4.011  15.649  -5.367  1    98.78  ? 40  GLU A CA  1 -0.037 0.143  -0.013 
ATOM   109   C  C   . GLU A 1 51  ? -4.427  16.711  -6.386  1    104.24 ? 40  GLU A C   1 -0.041 0.153  -0.016 
ATOM   110   O  O   . GLU A 1 51  ? -4.16   17.901  -6.182  1    98.51  ? 40  GLU A O   1 -0.038 0.164  -0.015 
ATOM   111   C  CB  . GLU A 1 51  ? -2.641  15.075  -5.73   1    105.56 ? 40  GLU A CB  1 -0.024 0.138  -0.014 
ATOM   112   C  CG  . GLU A 1 51  ? -2.016  14.296  -4.587  1    115.34 ? 40  GLU A CG  1 -0.018 0.131  -0.011 
ATOM   113   C  CD  . GLU A 1 51  ? -0.528  13.966  -4.77   1    127.6  ? 40  GLU A CD  1 -0.005 0.128  -0.012 
ATOM   114   O  OE1 . GLU A 1 51  ? -0.072  12.99   -4.112  1    129.62 ? 40  GLU A OE1 1 -0.001 0.119  -0.01  
ATOM   115   O  OE2 . GLU A 1 51  ? 0.181   14.677  -5.526  1    122.78 ? 40  GLU A OE2 1 0.002  0.135  -0.014 
ATOM   116   N  N   . GLN A 1 52  ? -5.072  16.312  -7.493  1    106.13 ? 41  GLN A N   1 -0.046 0.149  -0.019 
ATOM   117   C  CA  . GLN A 1 52  ? -5.441  17.31   -8.492  1    106.47 ? 41  GLN A CA  1 -0.05  0.159  -0.021 
ATOM   118   C  C   . GLN A 1 52  ? -6.719  18.053  -8.107  1    104.12 ? 41  GLN A C   1 -0.062 0.165  -0.02  
ATOM   119   O  O   . GLN A 1 52  ? -7.553  18.351  -8.975  1    95.16  ? 41  GLN A O   1 -0.069 0.168  -0.022 
ATOM   120   C  CB  . GLN A 1 52  ? -5.647  16.725  -9.894  1    111.55 ? 41  GLN A CB  1 -0.052 0.153  -0.025 
ATOM   121   C  CG  . GLN A 1 52  ? -4.857  15.505  -10.298 1    112.62 ? 41  GLN A CG  1 -0.045 0.142  -0.026 
ATOM   122   C  CD  . GLN A 1 52  ? -3.374  15.761  -10.376 1    117.79 ? 41  GLN A CD  1 -0.031 0.144  -0.026 
ATOM   123   O  OE1 . GLN A 1 52  ? -2.928  16.824  -10.808 1    110.42 ? 41  GLN A OE1 1 -0.027 0.154  -0.027 
ATOM   124   N  NE2 . GLN A 1 52  ? -2.586  14.777  -9.936  1    123.64 ? 41  GLN A NE2 1 -0.024 0.135  -0.025 
ATOM   125   N  N   . MET A 1 53  ? -6.903  18.354  -6.812  1    104.59 ? 42  MET A N   1 -0.063 0.168  -0.017 
ATOM   126   C  CA  . MET A 1 53  ? -8.077  19.103  -6.375  1    101.36 ? 42  MET A CA  1 -0.074 0.175  -0.016 
ATOM   127   C  C   . MET A 1 53  ? -7.703  20.339  -5.574  1    104.41 ? 42  MET A C   1 -0.071 0.186  -0.014 
ATOM   128   O  O   . MET A 1 53  ? -8.588  20.96   -4.972  1    103.65 ? 42  MET A O   1 -0.079 0.192  -0.012 
ATOM   129   C  CB  . MET A 1 53  ? -9.025  18.208  -5.572  1    94.92  ? 42  MET A CB  1 -0.083 0.167  -0.014 
ATOM   130   C  CG  . MET A 1 53  ? -9.2    16.807  -6.132  1    94.7   ? 42  MET A CG  1 -0.084 0.154  -0.015 
ATOM   131   S  SD  . MET A 1 53  ? -10.561 15.812  -5.449  1    97.58  ? 42  MET A SD  1 -0.097 0.145  -0.014 
ATOM   132   C  CE  . MET A 1 53  ? -10.51  16.365  -3.763  1    104.35 ? 42  MET A CE  1 -0.096 0.15   -0.009 
ATOM   133   N  N   . GLN A 1 54  ? -6.425  20.722  -5.558  1    105.23 ? 43  GLN A N   1 -0.059 0.19   -0.014 
ATOM   134   C  CA  . GLN A 1 54  ? -6.024  21.906  -4.803  1    107.44 ? 43  GLN A CA  1 -0.055 0.201  -0.012 
ATOM   135   C  C   . GLN A 1 54  ? -6.638  23.165  -5.414  1    107.64 ? 43  GLN A C   1 -0.061 0.212  -0.014 
ATOM   136   O  O   . GLN A 1 54  ? -6.972  23.218  -6.599  1    115.13 ? 43  GLN A O   1 -0.064 0.213  -0.016 
ATOM   137   C  CB  . GLN A 1 54  ? -4.497  22.031  -4.777  1    106.57 ? 43  GLN A CB  1 -0.041 0.202  -0.012 
ATOM   138   C  CG  . GLN A 1 54  ? -3.781  20.695  -4.845  1    108.66 ? 43  GLN A CG  1 -0.035 0.19   -0.012 
ATOM   139   C  CD  . GLN A 1 54  ? -2.297  20.813  -4.574  1    114.69 ? 43  GLN A CD  1 -0.021 0.191  -0.011 
ATOM   140   O  OE1 . GLN A 1 54  ? -1.851  21.712  -3.852  1    120.74 ? 43  GLN A OE1 1 -0.017 0.199  -0.01  
ATOM   141   N  NE2 . GLN A 1 54  ? -1.52   19.903  -5.152  1    117.34 ? 43  GLN A NE2 1 -0.014 0.182  -0.013 
ATOM   142   N  N   . ARG A 1 55  ? -6.782  24.183  -4.578  1    103.19 ? 44  ARG A N   1 -0.062 0.222  -0.011 
ATOM   143   C  CA  . ARG A 1 55  ? -7.378  25.467  -4.949  1    108.07 ? 44  ARG A CA  1 -0.068 0.233  -0.012 
ATOM   144   C  C   . ARG A 1 55  ? -8.886  25.363  -5.2    1    108.9  ? 44  ARG A C   1 -0.081 0.232  -0.013 
ATOM   145   O  O   . ARG A 1 55  ? -9.568  26.382  -5.394  1    104.16 ? 44  ARG A O   1 -0.088 0.242  -0.013 
ATOM   146   C  CB  . ARG A 1 55  ? -6.692  26.06   -6.168  1    113.19 ? 44  ARG A CB  1 -0.061 0.239  -0.015 
ATOM   147   C  CG  . ARG A 1 55  ? -5.203  26.244  -5.997  1    118    ? 44  ARG A CG  1 -0.048 0.241  -0.015 
ATOM   148   C  CD  . ARG A 1 55  ? -4.786  27.7    -6.152  1    122.79 ? 44  ARG A CD  1 -0.044 0.254  -0.015 
ATOM   149   N  NE  . ARG A 1 55  ? -3.335  27.828  -6.053  1    133.72 ? 44  ARG A NE  1 -0.031 0.255  -0.015 
ATOM   150   C  CZ  . ARG A 1 55  ? -2.669  28.977  -6.055  1    137.23 ? 44  ARG A CZ  1 -0.024 0.266  -0.015 
ATOM   151   N  NH1 . ARG A 1 55  ? -3.292  30.138  -6.199  1    133.47 ? 44  ARG A NH1 1 -0.03  0.276  -0.015 
ATOM   152   N  NH2 . ARG A 1 55  ? -1.345  28.961  -5.902  1    136.64 ? 44  ARG A NH2 1 -0.012 0.265  -0.015 
ATOM   153   N  N   . MET A 1 56  ? -9.417  24.133  -5.14   1    104.6  ? 45  MET A N   1 -0.086 0.221  -0.013 
ATOM   154   C  CA  . MET A 1 56  ? -10.83  23.954  -5.402  1    107.24 ? 45  MET A CA  1 -0.099 0.22   -0.013 
ATOM   155   C  C   . MET A 1 56  ? -11.656 24.373  -4.163  1    104.11 ? 45  MET A C   1 -0.107 0.223  -0.01  
ATOM   156   O  O   . MET A 1 56  ? -11.525 23.74   -3.141  1    111.97 ? 45  MET A O   1 -0.106 0.218  -0.008 
ATOM   157   C  CB  . MET A 1 56  ? -11.141 22.512  -5.774  1    106.34 ? 45  MET A CB  1 -0.102 0.206  -0.014 
ATOM   158   C  CG  . MET A 1 56  ? -10.547 22.107  -7.131  1    103.45 ? 45  MET A CG  1 -0.097 0.203  -0.018 
ATOM   159   S  SD  . MET A 1 56  ? -11.452 20.718  -7.843  1    104.31 ? 45  MET A SD  1 -0.105 0.19   -0.02  
ATOM   160   C  CE  . MET A 1 56  ? -13.1   21.427  -7.7    1    114.9  ? 45  MET A CE  1 -0.12  0.196  -0.019 
ATOM   161   N  N   . PRO A 1 57  ? -12.491 25.399  -4.226  1    99.46  ? 46  PRO A N   1 -0.114 0.233  -0.011 
ATOM   162   C  CA  . PRO A 1 57  ? -13.058 26.001  -3.032  1    112.52 ? 46  PRO A CA  1 -0.12  0.238  -0.008 
ATOM   163   C  C   . PRO A 1 57  ? -14.006 25.077  -2.32   1    114.91 ? 46  PRO A C   1 -0.128 0.23   -0.006 
ATOM   164   O  O   . PRO A 1 57  ? -14.745 24.29   -2.91   1    111.47 ? 46  PRO A O   1 -0.135 0.223  -0.007 
ATOM   165   C  CB  . PRO A 1 57  ? -13.771 27.229  -3.575  1    105.9  ? 46  PRO A CB  1 -0.126 0.25   -0.009 
ATOM   166   C  CG  . PRO A 1 57  ? -14.28  26.762  -4.812  1    109.89 ? 46  PRO A CG  1 -0.131 0.245  -0.012 
ATOM   167   C  CD  . PRO A 1 57  ? -13.158 25.947  -5.418  1    115.1  ? 46  PRO A CD  1 -0.121 0.238  -0.014 
ATOM   168   N  N   . ALA A 1 58  ? -13.981 25.199  -0.966  1    104.58 ? 47  ALA A N   1 -0.128 0.231  -0.002 
ATOM   169   C  CA  . ALA A 1 58  ? -15.01  24.66   -0.068  1    107.65 ? 47  ALA A CA  1 -0.138 0.226  -0.0   
ATOM   170   C  C   . ALA A 1 58  ? -15.496 25.77   0.858   1    113.86 ? 47  ALA A C   1 -0.142 0.236  0.002  
ATOM   171   O  O   . ALA A 1 58  ? -14.783 26.744  1.134   1    116.17 ? 47  ALA A O   1 -0.135 0.245  0.003  
ATOM   172   C  CB  . ALA A 1 58  ? -14.462 23.487  0.757   1    107.25 ? 47  ALA A CB  1 -0.133 0.215  0.002  
ATOM   173   N  N   . GLY A 1 59  ? -16.728 25.606  1.341   1    111.39 ? 48  GLY A N   1 -0.153 0.235  0.003  
ATOM   174   C  CA  . GLY A 1 59  ? -17.382 26.588  2.221   1    112.73 ? 48  GLY A CA  1 -0.159 0.244  0.006  
ATOM   175   C  C   . GLY A 1 59  ? -16.766 26.583  3.593   1    115.1  ? 48  GLY A C   1 -0.154 0.244  0.009  
ATOM   176   O  O   . GLY A 1 59  ? -17.262 27.22   4.526   1    114.41 ? 48  GLY A O   1 -0.158 0.249  0.011  
ATOM   177   N  N   . GLY A 1 60  ? -15.672 25.831  3.717   1    115.16 ? 49  GLY A N   1 -0.144 0.237  0.009  
ATOM   178   C  CA  . GLY A 1 60  ? -14.854 25.843  4.887   1    109.73 ? 49  GLY A CA  1 -0.136 0.237  0.012  
ATOM   179   C  C   . GLY A 1 60  ? -13.523 26.543  4.658   1    115.88 ? 49  GLY A C   1 -0.124 0.243  0.012  
ATOM   180   O  O   . GLY A 1 60  ? -13.321 27.256  3.668   1    122.56 ? 49  GLY A O   1 -0.122 0.25   0.009  
ATOM   181   N  N   . GLU A 1 61  ? -12.608 26.315  5.583   1    113.69 ? 50  GLU A N   1 -0.116 0.241  0.014  
ATOM   182   C  CA  . GLU A 1 61  ? -11.316 26.961  5.67    1    117.69 ? 50  GLU A CA  1 -0.104 0.247  0.014  
ATOM   183   C  C   . GLU A 1 61  ? -10.237 26.243  4.869   1    117.69 ? 50  GLU A C   1 -0.094 0.24   0.012  
ATOM   184   O  O   . GLU A 1 61  ? -9.189  26.84   4.564   1    118.59 ? 50  GLU A O   1 -0.084 0.246  0.011  
ATOM   185   C  CB  . GLU A 1 61  ? -10.916 27.03   7.151   1    118.69 ? 50  GLU A CB  1 -0.1   0.248  0.018  
ATOM   186   C  CG  . GLU A 1 61  ? -10.678 25.637  7.821   1    125.34 ? 50  GLU A CG  1 -0.098 0.235  0.02   
ATOM   187   C  CD  . GLU A 1 61  ? -11.923 24.722  7.942   1    134.48 ? 50  GLU A CD  1 -0.109 0.227  0.02   
ATOM   188   O  OE1 . GLU A 1 61  ? -11.899 23.774  8.795   1    131.11 ? 50  GLU A OE1 1 -0.109 0.218  0.022  
ATOM   189   O  OE2 . GLU A 1 61  ? -12.905 24.938  7.192   1    128.87 ? 50  GLU A OE2 1 -0.118 0.229  0.018  
ATOM   190   N  N   . GLU A 1 62  ? -10.462 24.983  4.536   1    114.71 ? 51  GLU A N   1 -0.096 0.229  0.011  
ATOM   191   C  CA  . GLU A 1 62  ? -9.548  24.165  3.757   1    113.67 ? 51  GLU A CA  1 -0.087 0.221  0.009  
ATOM   192   C  C   . GLU A 1 62  ? -10.105 23.984  2.35    1    111.47 ? 51  GLU A C   1 -0.093 0.22   0.006  
ATOM   193   O  O   . GLU A 1 62  ? -11.326 23.993  2.15    1    106.27 ? 51  GLU A O   1 -0.104 0.22   0.005  
ATOM   194   C  CB  . GLU A 1 62  ? -9.366  22.804  4.427   1    108.47 ? 51  GLU A CB  1 -0.086 0.209  0.011  
ATOM   195   C  CG  . GLU A 1 62  ? -10.629 22.386  5.174   1    111.2  ? 51  GLU A CG  1 -0.097 0.205  0.013  
ATOM   196   C  CD  . GLU A 1 62  ? -10.68  20.902  5.501   1    109.32 ? 51  GLU A CD  1 -0.098 0.192  0.014  
ATOM   197   O  OE1 . GLU A 1 62  ? -9.601  20.262  5.631   1    101.12 ? 51  GLU A OE1 1 -0.088 0.186  0.014  
ATOM   198   O  OE2 . GLU A 1 62  ? -11.817 20.38   5.615   1    106.52 ? 51  GLU A OE2 1 -0.108 0.187  0.014  
ATOM   199   N  N   . ASP A 1 63  ? -9.207  23.826  1.372   1    107    ? 52  ASP A N   1 -0.084 0.218  0.003  
ATOM   200   C  CA  . ASP A 1 63  ? -9.661  23.521  0.02    1    107.8  ? 52  ASP A CA  1 -0.089 0.216  0.0    
ATOM   201   C  C   . ASP A 1 63  ? -10.205 22.097  -0.029  1    103.92 ? 52  ASP A C   1 -0.094 0.202  -0.0   
ATOM   202   O  O   . ASP A 1 63  ? -10.052 21.307  0.908   1    107.09 ? 52  ASP A O   1 -0.092 0.195  0.002  
ATOM   203   C  CB  . ASP A 1 63  ? -8.535  23.715  -1.015  1    109.28 ? 52  ASP A CB  1 -0.078 0.217  -0.003 
ATOM   204   C  CG  . ASP A 1 63  ? -7.304  22.819  -0.762  1    110.56 ? 52  ASP A CG  1 -0.067 0.209  -0.002 
ATOM   205   O  OD1 . ASP A 1 63  ? -7.439  21.729  -0.156  1    107.07 ? 52  ASP A OD1 1 -0.068 0.199  -0.0   
ATOM   206   O  OD2 . ASP A 1 63  ? -6.182  23.222  -1.172  1    105.21 ? 52  ASP A OD2 1 -0.057 0.213  -0.003 
ATOM   207   N  N   . GLN A 1 64  ? -10.848 21.768  -1.144  1    101.51 ? 53  GLN A N   1 -0.099 0.199  -0.003 
ATOM   208   C  CA  . GLN A 1 64  ? -11.398 20.43   -1.287  1    100.3  ? 53  GLN A CA  1 -0.104 0.187  -0.003 
ATOM   209   C  C   . GLN A 1 64  ? -10.315 19.36   -1.262  1    102.47 ? 53  GLN A C   1 -0.095 0.177  -0.003 
ATOM   210   O  O   . GLN A 1 64  ? -10.615 18.207  -0.923  1    100.57 ? 53  GLN A O   1 -0.097 0.167  -0.002 
ATOM   211   C  CB  . GLN A 1 64  ? -12.217 20.344  -2.569  1    96.81  ? 53  GLN A CB  1 -0.112 0.186  -0.006 
ATOM   212   C  CG  . GLN A 1 64  ? -13.535 21.08   -2.473  1    98.2   ? 53  GLN A CG  1 -0.124 0.193  -0.006 
ATOM   213   C  CD  . GLN A 1 64  ? -14.614 20.173  -1.945  1    98.51  ? 53  GLN A CD  1 -0.134 0.185  -0.005 
ATOM   214   O  OE1 . GLN A 1 64  ? -14.405 18.967  -1.875  1    99.39  ? 53  GLN A OE1 1 -0.132 0.174  -0.005 
ATOM   215   N  NE2 . GLN A 1 64  ? -15.773 20.735  -1.574  1    94.98  ? 53  GLN A NE2 1 -0.145 0.19   -0.004 
ATOM   216   N  N   . TYR A 1 65  ? -9.066  19.713  -1.586  1    101.24 ? 54  TYR A N   1 -0.083 0.181  -0.004 
ATOM   217   C  CA  . TYR A 1 65  ? -7.983  18.73   -1.543  1    106.56 ? 54  TYR A CA  1 -0.073 0.172  -0.004 
ATOM   218   C  C   . TYR A 1 65  ? -7.743  18.225  -0.12   1    103.76 ? 54  TYR A C   1 -0.071 0.167  -0.0   
ATOM   219   O  O   . TYR A 1 65  ? -7.822  17.019  0.146   1    99.67  ? 54  TYR A O   1 -0.072 0.156  0.0    
ATOM   220   C  CB  . TYR A 1 65  ? -6.697  19.324  -2.123  1    106.21 ? 54  TYR A CB  1 -0.061 0.177  -0.005 
ATOM   221   C  CG  . TYR A 1 65  ? -5.42   18.607  -1.677  1    109.54 ? 54  TYR A CG  1 -0.05  0.171  -0.004 
ATOM   222   C  CD1 . TYR A 1 65  ? -5.209  17.251  -1.96   1    103.89 ? 54  TYR A CD1 1 -0.048 0.158  -0.005 
ATOM   223   C  CD2 . TYR A 1 65  ? -4.423  19.29   -0.985  1    108.01 ? 54  TYR A CD2 1 -0.041 0.177  -0.002 
ATOM   224   C  CE1 . TYR A 1 65  ? -4.037  16.597  -1.56   1    97.89  ? 54  TYR A CE1 1 -0.037 0.152  -0.004 
ATOM   225   C  CE2 . TYR A 1 65  ? -3.253  18.65   -0.586  1    106.87 ? 54  TYR A CE2 1 -0.03  0.171  -0.001 
ATOM   226   C  CZ  . TYR A 1 65  ? -3.061  17.305  -0.881  1    106.01 ? 54  TYR A CZ  1 -0.028 0.159  -0.002 
ATOM   227   O  OH  . TYR A 1 65  ? -1.895  16.672  -0.481  1    108.2  ? 54  TYR A OH  1 -0.017 0.153  -0.001 
ATOM   228   N  N   . LEU A 1 66  ? -7.416  19.135  0.802   1    103.39 ? 55  LEU A N   1 -0.068 0.175  0.002  
ATOM   229   C  CA  . LEU A 1 66  ? -7.273  18.756  2.205   1    101.06 ? 55  LEU A CA  1 -0.067 0.172  0.006  
ATOM   230   C  C   . LEU A 1 66  ? -8.533  18.073  2.722   1    98.31  ? 55  LEU A C   1 -0.078 0.166  0.007  
ATOM   231   O  O   . LEU A 1 66  ? -8.467  16.991  3.32    1    93.57  ? 55  LEU A O   1 -0.078 0.156  0.008  
ATOM   232   C  CB  . LEU A 1 66  ? -6.95   19.988  3.049   1    99.62  ? 55  LEU A CB  1 -0.064 0.183  0.008  
ATOM   233   C  CG  . LEU A 1 66  ? -5.485  20.182  3.431   1    102.67 ? 55  LEU A CG  1 -0.05  0.185  0.009  
ATOM   234   C  CD1 . LEU A 1 66  ? -4.628  20.532  2.222   1    102.16 ? 55  LEU A CD1 1 -0.042 0.188  0.006  
ATOM   235   C  CD2 . LEU A 1 66  ? -5.364  21.25   4.528   1    114.31 ? 55  LEU A CD2 1 -0.049 0.195  0.011  
ATOM   236   N  N   . ARG A 1 67  ? -9.696  18.685  2.481   1    95.15  ? 56  ARG A N   1 -0.089 0.171  0.006  
ATOM   237   C  CA  . ARG A 1 67  ? -10.949 18.141  2.999   1    95.17  ? 56  ARG A CA  1 -0.1   0.166  0.007  
ATOM   238   C  C   . ARG A 1 67  ? -11.137 16.672  2.616   1    96.33  ? 56  ARG A C   1 -0.102 0.153  0.007  
ATOM   239   O  O   . ARG A 1 67  ? -11.369 15.824  3.481   1    99.69  ? 56  ARG A O   1 -0.104 0.145  0.009  
ATOM   240   C  CB  . ARG A 1 67  ? -12.115 18.987  2.497   1    93.1   ? 56  ARG A CB  1 -0.111 0.174  0.006  
ATOM   241   C  CG  . ARG A 1 67  ? -13.487 18.44   2.832   1    91.9   ? 56  ARG A CG  1 -0.124 0.169  0.007  
ATOM   242   C  CD  . ARG A 1 67  ? -14.561 19.194  2.029   1    94.9   ? 56  ARG A CD  1 -0.133 0.176  0.005  
ATOM   243   N  NE  . ARG A 1 67  ? -15.91  18.796  2.411   1    97.47  ? 56  ARG A NE  1 -0.146 0.172  0.006  
ATOM   244   C  CZ  . ARG A 1 67  ? -16.75  18.14   1.619   1    101.48 ? 56  ARG A CZ  1 -0.153 0.166  0.004  
ATOM   245   N  NH1 . ARG A 1 67  ? -16.449 17.882  0.348   1    103.16 ? 56  ARG A NH1 1 -0.151 0.164  0.001  
ATOM   246   N  NH2 . ARG A 1 67  ? -17.929 17.746  2.109   1    94.71  ? 56  ARG A NH2 1 -0.164 0.163  0.005  
ATOM   247   N  N   . ILE A 1 68  ? -11.026 16.35   1.325   1    100.08 ? 57  ILE A N   1 -0.101 0.15   0.003  
ATOM   248   C  CA  . ILE A 1 68  ? -11.265 14.974  0.894   1    92.99  ? 57  ILE A CA  1 -0.103 0.137  0.002  
ATOM   249   C  C   . ILE A 1 68  ? -10.117 14.076  1.325   1    87.71  ? 57  ILE A C   1 -0.093 0.129  0.003  
ATOM   250   O  O   . ILE A 1 68  ? -10.336 12.913  1.681   1    86.46  ? 57  ILE A O   1 -0.095 0.118  0.004  
ATOM   251   C  CB  . ILE A 1 68  ? -11.507 14.925  -0.637  1    98.9   ? 57  ILE A CB  1 -0.105 0.137  -0.002 
ATOM   252   C  CG1 . ILE A 1 68  ? -12.999 14.956  -0.972  1    92.81  ? 57  ILE A CG1 1 -0.119 0.137  -0.002 
ATOM   253   C  CG2 . ILE A 1 68  ? -10.938 13.666  -1.26   1    97.58  ? 57  ILE A CG2 1 -0.1   0.125  -0.003 
ATOM   254   C  CD1 . ILE A 1 68  ? -13.681 16.251  -0.665  1    97.98  ? 57  ILE A CD1 1 -0.125 0.149  -0.002 
ATOM   255   N  N   . LYS A 1 69  ? -8.888  14.595  1.327   1    89.73  ? 58  LYS A N   1 -0.081 0.134  0.003  
ATOM   256   C  CA  . LYS A 1 69  ? -7.737  13.82   1.799   1    96.67  ? 58  LYS A CA  1 -0.071 0.127  0.004  
ATOM   257   C  C   . LYS A 1 69  ? -7.898  13.39   3.259   1    101.61 ? 58  LYS A C   1 -0.072 0.123  0.008  
ATOM   258   O  O   . LYS A 1 69  ? -7.6    12.242  3.62    1    98.75  ? 58  LYS A O   1 -0.07  0.112  0.009  
ATOM   259   C  CB  . LYS A 1 69  ? -6.46   14.642  1.645   1    93.48  ? 58  LYS A CB  1 -0.059 0.134  0.004  
ATOM   260   C  CG  . LYS A 1 69  ? -5.215  13.947  2.139   1    82.73  ? 58  LYS A CG  1 -0.048 0.128  0.005  
ATOM   261   C  CD  . LYS A 1 69  ? -4.127  14.964  2.384   1    83.91  ? 58  LYS A CD  1 -0.038 0.137  0.006  
ATOM   262   C  CE  . LYS A 1 69  ? -2.836  14.53   1.734   1    99.06  ? 58  LYS A CE  1 -0.026 0.133  0.004  
ATOM   263   N  NZ  . LYS A 1 69  ? -1.635  14.788  2.585   1    107.9  ? 58  LYS A NZ  1 -0.015 0.136  0.006  
ATOM   264   N  N   . HIS A 1 70  ? -8.328  14.315  4.123   1    94.49  ? 59  HIS A N   1 -0.076 0.131  0.01   
ATOM   265   C  CA  . HIS A 1 70  ? -8.547  13.972  5.52    1    98.57  ? 59  HIS A CA  1 -0.078 0.128  0.014  
ATOM   266   C  C   . HIS A 1 70  ? -9.537  12.816  5.651   1    101.19 ? 59  HIS A C   1 -0.087 0.117  0.014  
ATOM   267   O  O   . HIS A 1 70  ? -9.291  11.85   6.386   1    109.14 ? 59  HIS A O   1 -0.085 0.109  0.016  
ATOM   268   C  CB  . HIS A 1 70  ? -9.035  15.206  6.292   1    101.24 ? 59  HIS A CB  1 -0.083 0.139  0.016  
ATOM   269   C  CG  . HIS A 1 70  ? -7.993  16.271  6.474   1    99.98  ? 59  HIS A CG  1 -0.073 0.149  0.016  
ATOM   270   N  ND1 . HIS A 1 70  ? -6.637  16.011  6.446   1    100.71 ? 59  HIS A ND1 1 -0.061 0.147  0.016  
ATOM   271   C  CD2 . HIS A 1 70  ? -8.111  17.605  6.682   1    98.18  ? 59  HIS A CD2 1 -0.074 0.161  0.017  
ATOM   272   C  CE1 . HIS A 1 70  ? -5.966  17.134  6.639   1    99.57  ? 59  HIS A CE1 1 -0.055 0.157  0.017  
ATOM   273   N  NE2 . HIS A 1 70  ? -6.836  18.118  6.78    1    100.6  ? 59  HIS A NE2 1 -0.063 0.166  0.017  
ATOM   274   N  N   . MET A 1 71  ? -10.667 12.894  4.942   1    95.2   ? 60  MET A N   1 -0.098 0.118  0.012  
ATOM   275   C  CA  . MET A 1 71  ? -11.654 11.822  5.035   1    96.37  ? 60  MET A CA  1 -0.107 0.108  0.013  
ATOM   276   C  C   . MET A 1 71  ? -11.075 10.496  4.55    1    103.62 ? 60  MET A C   1 -0.101 0.096  0.011  
ATOM   277   O  O   . MET A 1 71  ? -11.346 9.44    5.139   1    105.07 ? 60  MET A O   1 -0.104 0.087  0.013  
ATOM   278   C  CB  . MET A 1 71  ? -12.909 12.187  4.242   1    87.18  ? 60  MET A CB  1 -0.118 0.112  0.011  
ATOM   279   C  CG  . MET A 1 71  ? -13.413 13.593  4.51    1    87.56  ? 60  MET A CG  1 -0.123 0.125  0.011  
ATOM   280   S  SD  . MET A 1 71  ? -15.159 13.674  4.105   1    95.45  ? 60  MET A SD  1 -0.139 0.125  0.01   
ATOM   281   C  CE  . MET A 1 71  ? -15.57  15.383  4.493   1    78.64  ? 60  MET A CE  1 -0.143 0.141  0.011  
ATOM   282   N  N   . SER A 1 72  ? -10.253 10.535  3.493   1    100.52 ? 61  SER A N   1 -0.094 0.097  0.009  
ATOM   283   C  CA  . SER A 1 72  ? -9.71   9.311   2.912   1    100.8  ? 61  SER A CA  1 -0.089 0.085  0.007  
ATOM   284   C  C   . SER A 1 72  ? -8.695  8.648   3.841   1    105.58 ? 61  SER A C   1 -0.08  0.079  0.01   
ATOM   285   O  O   . SER A 1 72  ? -8.721  7.423   4.03    1    105.23 ? 61  SER A O   1 -0.08  0.068  0.01   
ATOM   286   C  CB  . SER A 1 72  ? -9.09   9.638   1.563   1    100.99 ? 61  SER A CB  1 -0.083 0.088  0.004  
ATOM   287   O  OG  . SER A 1 72  ? -9.54   10.914  1.144   1    97.25  ? 61  SER A OG  1 -0.087 0.1    0.003  
ATOM   288   N  N   . ALA A 1 73  ? -7.805  9.439   4.445   1    109.5  ? 62  ALA A N   1 -0.072 0.087  0.011  
ATOM   289   C  CA  . ALA A 1 73  ? -6.877  8.882   5.432   1    106.2  ? 62  ALA A CA  1 -0.063 0.081  0.014  
ATOM   290   C  C   . ALA A 1 73  ? -7.628  8.18    6.558   1    107.91 ? 62  ALA A C   1 -0.07  0.075  0.016  
ATOM   291   O  O   . ALA A 1 73  ? -7.262  7.069   6.958   1    110.6  ? 62  ALA A O   1 -0.067 0.065  0.017  
ATOM   292   C  CB  . ALA A 1 73  ? -5.973  9.983   5.989   1    96.59  ? 62  ALA A CB  1 -0.055 0.091  0.015  
ATOM   293   N  N   . LEU A 1 74  ? -8.699  8.799   7.064   1    104.89 ? 63  LEU A N   1 -0.08  0.081  0.018  
ATOM   294   C  CA  . LEU A 1 74  ? -9.499  8.162   8.104   1    99.35  ? 63  LEU A CA  1 -0.087 0.075  0.02   
ATOM   295   C  C   . LEU A 1 74  ? -10.094 6.843   7.62    1    107.04 ? 63  LEU A C   1 -0.093 0.063  0.019  
ATOM   296   O  O   . LEU A 1 74  ? -10.025 5.828   8.325   1    108.3  ? 63  LEU A O   1 -0.092 0.053  0.021  
ATOM   297   C  CB  . LEU A 1 74  ? -10.604 9.108   8.574   1    98.26  ? 63  LEU A CB  1 -0.097 0.083  0.021  
ATOM   298   C  CG  . LEU A 1 74  ? -11.257 8.75    9.916   1    105.53 ? 63  LEU A CG  1 -0.103 0.08   0.025  
ATOM   299   C  CD1 . LEU A 1 74  ? -10.198 8.706   11.028  1    108.92 ? 63  LEU A CD1 1 -0.093 0.08   0.028  
ATOM   300   C  CD2 . LEU A 1 74  ? -12.389 9.719   10.286  1    101.04 ? 63  LEU A CD2 1 -0.114 0.089  0.026  
ATOM   301   N  N   . ILE A 1 75  ? -10.687 6.843   6.415   1    104.17 ? 64  ILE A N   1 -0.098 0.063  0.016  
ATOM   302   C  CA  . ILE A 1 75  ? -11.375 5.661   5.896   1    99.63  ? 64  ILE A CA  1 -0.104 0.052  0.015  
ATOM   303   C  C   . ILE A 1 75  ? -10.392 4.519   5.675   1    104.64 ? 64  ILE A C   1 -0.095 0.041  0.014  
ATOM   304   O  O   . ILE A 1 75  ? -10.72  3.345   5.889   1    103.49 ? 64  ILE A O   1 -0.098 0.031  0.015  
ATOM   305   C  CB  . ILE A 1 75  ? -12.128 6.012   4.6     1    106.14 ? 64  ILE A CB  1 -0.111 0.055  0.011  
ATOM   306   C  CG1 . ILE A 1 75  ? -13.383 6.823   4.889   1    104.05 ? 64  ILE A CG1 1 -0.123 0.063  0.012  
ATOM   307   C  CG2 . ILE A 1 75  ? -12.49  4.762   3.796   1    103.77 ? 64  ILE A CG2 1 -0.114 0.044  0.009  
ATOM   308   C  CD1 . ILE A 1 75  ? -14.024 7.322   3.587   1    101.74 ? 64  ILE A CD1 1 -0.129 0.067  0.009  
ATOM   309   N  N   . LYS A 1 76  ? -9.173  4.841   5.236   1    103.71 ? 65  LYS A N   1 -0.084 0.044  0.013  
ATOM   310   C  CA  . LYS A 1 76  ? -8.168  3.8     5.062   1    105.79 ? 65  LYS A CA  1 -0.075 0.035  0.013  
ATOM   311   C  C   . LYS A 1 76  ? -7.725  3.227   6.401   1    112.25 ? 65  LYS A C   1 -0.071 0.03   0.016  
ATOM   312   O  O   . LYS A 1 76  ? -7.445  2.027   6.498   1    115.76 ? 65  LYS A O   1 -0.068 0.019  0.016  
ATOM   313   C  CB  . LYS A 1 76  ? -6.97   4.349   4.285   1    109.42 ? 65  LYS A CB  1 -0.064 0.04   0.011  
ATOM   314   C  CG  . LYS A 1 76  ? -7.311  4.791   2.856   1    109.83 ? 65  LYS A CG  1 -0.067 0.044  0.007  
ATOM   315   C  CD  . LYS A 1 76  ? -6.066  5.05    2.014   1    106.71 ? 65  LYS A CD  1 -0.056 0.046  0.005  
ATOM   316   C  CE  . LYS A 1 76  ? -5.379  6.366   2.373   1    111.94 ? 65  LYS A CE  1 -0.049 0.058  0.006  
ATOM   317   N  NZ  . LYS A 1 76  ? -6.037  7.567   1.763   1    110.24 ? 65  LYS A NZ  1 -0.055 0.069  0.004  
ATOM   318   N  N   . LYS A 1 77  ? -7.693  4.062   7.447   1    116    ? 66  LYS A N   1 -0.07  0.037  0.019  
ATOM   319   C  CA  . LYS A 1 77  ? -7.153  3.675   8.75    1    121.8  ? 66  LYS A CA  1 -0.066 0.034  0.022  
ATOM   320   C  C   . LYS A 1 77  ? -8.155  2.866   9.574   1    123.91 ? 66  LYS A C   1 -0.075 0.026  0.024  
ATOM   321   O  O   . LYS A 1 77  ? -7.757  1.956   10.311  1    128.15 ? 66  LYS A O   1 -0.071 0.018  0.026  
ATOM   322   C  CB  . LYS A 1 77  ? -6.7    4.932   9.509   1    120.52 ? 66  LYS A CB  1 -0.061 0.045  0.024  
ATOM   323   C  CG  . LYS A 1 77  ? -6.62   4.801   11.03   1    125.99 ? 66  LYS A CG  1 -0.061 0.044  0.028  
ATOM   324   C  CD  . LYS A 1 77  ? -5.373  4.026   11.495  1    135.38 ? 66  LYS A CD  1 -0.049 0.037  0.029  
ATOM   325   C  CE  . LYS A 1 77  ? -5.169  4.106   13.022  1    129.82 ? 66  LYS A CE  1 -0.047 0.038  0.033  
ATOM   326   N  NZ  . LYS A 1 77  ? -3.845  3.542   13.462  1    120.99 ? 66  LYS A NZ  1 -0.035 0.032  0.034  
ATOM   327   N  N   . TYR A 1 78  ? -9.45   3.183   9.475   1    120.75 ? 67  TYR A N   1 -0.087 0.029  0.024  
ATOM   328   C  CA  . TYR A 1 78  ? -10.502 2.387   10.107  1    119.36 ? 67  TYR A CA  1 -0.096 0.022  0.025  
ATOM   329   C  C   . TYR A 1 78  ? -10.461 0.962   9.558   1    124.66 ? 67  TYR A C   1 -0.096 0.009  0.024  
ATOM   330   O  O   . TYR A 1 78  ? -11.102 0.664   8.548   1    126.22 ? 67  TYR A O   1 -0.102 0.006  0.021  
ATOM   331   C  CB  . TYR A 1 78  ? -11.873 3.045   9.872   1    112.65 ? 67  TYR A CB  1 -0.109 0.028  0.025  
ATOM   332   C  CG  . TYR A 1 78  ? -13.07  2.462   10.619  1    112.26 ? 67  TYR A CG  1 -0.12  0.023  0.027  
ATOM   333   C  CD1 . TYR A 1 78  ? -13.346 1.098   10.609  1    117.7  ? 67  TYR A CD1 1 -0.122 0.01   0.026  
ATOM   334   C  CD2 . TYR A 1 78  ? -13.939 3.294   11.32   1    111.13 ? 67  TYR A CD2 1 -0.128 0.03   0.028  
ATOM   335   C  CE1 . TYR A 1 78  ? -14.448 0.568   11.287  1    121.19 ? 67  TYR A CE1 1 -0.132 0.005  0.028  
ATOM   336   C  CE2 . TYR A 1 78  ? -15.048 2.778   12.004  1    113.4  ? 67  TYR A CE2 1 -0.138 0.025  0.03   
ATOM   337   C  CZ  . TYR A 1 78  ? -15.3   1.41    11.986  1    119.75 ? 67  TYR A CZ  1 -0.14  0.013  0.03   
ATOM   338   O  OH  . TYR A 1 78  ? -16.392 0.877   12.661  1    114.62 ? 67  TYR A OH  1 -0.15  0.008  0.032  
ATOM   339   N  N   . GLY A 1 79  ? -9.69   0.088   10.208  1    132.12 ? 68  GLY A N   1 -0.089 0.001  0.025  
ATOM   340   C  CA  . GLY A 1 79  ? -9.618  -1.337  9.914   1    132.38 ? 68  GLY A CA  1 -0.088 -0.012 0.025  
ATOM   341   C  C   . GLY A 1 79  ? -9.827  -1.845  8.494   1    125.44 ? 68  GLY A C   1 -0.09  -0.017 0.021  
ATOM   342   O  O   . GLY A 1 79  ? -9.025  -1.572  7.596   1    121.45 ? 68  GLY A O   1 -0.083 -0.014 0.019  
ATOM   343   N  N   . ASP A 1 80  ? -10.906 -2.605  8.297   1    123.27 ? 69  ASP A N   1 -0.1   -0.024 0.021  
ATOM   344   C  CA  . ASP A 1 80  ? -11.187 -3.352  7.07    1    118.99 ? 69  ASP A CA  1 -0.103 -0.031 0.018  
ATOM   345   C  C   . ASP A 1 80  ? -12.587 -3.001  6.589   1    122.09 ? 69  ASP A C   1 -0.115 -0.028 0.016  
ATOM   346   O  O   . ASP A 1 80  ? -13.554 -3.65   6.998   1    129.64 ? 69  ASP A O   1 -0.124 -0.033 0.017  
ATOM   347   C  CB  . ASP A 1 80  ? -11.094 -4.852  7.298   1    123.82 ? 69  ASP A CB  1 -0.102 -0.044 0.018  
ATOM   348   C  CG  . ASP A 1 80  ? -9.753  -5.285  7.809   1    141.66 ? 69  ASP A CG  1 -0.089 -0.048 0.019  
ATOM   349   O  OD1 . ASP A 1 80  ? -8.739  -4.911  7.174   1    139.99 ? 69  ASP A OD1 1 -0.08  -0.045 0.018  
ATOM   350   O  OD2 . ASP A 1 80  ? -9.718  -5.988  8.85    1    145.45 ? 69  ASP A OD2 1 -0.089 -0.055 0.022  
ATOM   351   N  N   . LEU A 1 81  ? -12.703 -1.993  5.731   1    118.01 ? 70  LEU A N   1 -0.116 -0.018 0.014  
ATOM   352   C  CA  . LEU A 1 81  ? -13.931 -1.806  4.976   1    113.67 ? 70  LEU A CA  1 -0.128 -0.017 0.012  
ATOM   353   C  C   . LEU A 1 81  ? -13.676 -2.076  3.501   1    107.89 ? 70  LEU A C   1 -0.125 -0.019 0.009  
ATOM   354   O  O   . LEU A 1 81  ? -12.541 -1.956  3.025   1    103.26 ? 70  LEU A O   1 -0.115 -0.018 0.008  
ATOM   355   C  CB  . LEU A 1 81  ? -14.494 -0.388  5.143   1    113.18 ? 70  LEU A CB  1 -0.133 -0.004 0.013  
ATOM   356   C  CG  . LEU A 1 81  ? -14.471 0.297   6.506   1    115.42 ? 70  LEU A CG  1 -0.133 0.003  0.016  
ATOM   357   C  CD1 . LEU A 1 81  ? -13.214 1.137   6.577   1    108.26 ? 70  LEU A CD1 1 -0.121 0.01   0.016  
ATOM   358   C  CD2 . LEU A 1 81  ? -15.723 1.15    6.708   1    113.49 ? 70  LEU A CD2 1 -0.144 0.011  0.017  
ATOM   359   N  N   . PRO A 1 82  ? -14.704 -2.463  2.751   1    108.33 ? 71  PRO A N   1 -0.135 -0.023 0.007  
ATOM   360   C  CA  . PRO A 1 82  ? -14.536 -2.691  1.309   1    108.96 ? 71  PRO A CA  1 -0.133 -0.025 0.003  
ATOM   361   C  C   . PRO A 1 82  ? -14.315 -1.4    0.535   1    107.57 ? 71  PRO A C   1 -0.131 -0.013 0.001  
ATOM   362   O  O   . PRO A 1 82  ? -15.277 -0.777  0.074   1    105    ? 71  PRO A O   1 -0.14  -0.007 0.0    
ATOM   363   C  CB  . PRO A 1 82  ? -15.862 -3.351  0.91    1    109.89 ? 71  PRO A CB  1 -0.145 -0.031 0.002  
ATOM   364   C  CG  . PRO A 1 82  ? -16.849 -2.818  1.919   1    110.26 ? 71  PRO A CG  1 -0.154 -0.026 0.005  
ATOM   365   C  CD  . PRO A 1 82  ? -16.079 -2.733  3.203   1    110.03 ? 71  PRO A CD  1 -0.147 -0.025 0.008  
ATOM   366   N  N   . VAL A 1 83  ? -13.065 -0.985  0.369   1    107.27 ? 72  VAL A N   1 -0.12  -0.009 0.001  
ATOM   367   C  CA  . VAL A 1 83  ? -12.747 0.36    -0.096  1    107.82 ? 72  VAL A CA  1 -0.117 0.003  -0.0   
ATOM   368   C  C   . VAL A 1 83  ? -12.119 0.265   -1.485  1    104.97 ? 72  VAL A C   1 -0.111 0.002  -0.004 
ATOM   369   O  O   . VAL A 1 83  ? -11.155 -0.485  -1.688  1    105.7  ? 72  VAL A O   1 -0.102 -0.004 -0.004 
ATOM   370   C  CB  . VAL A 1 83  ? -11.844 1.093   0.921   1    106.12 ? 72  VAL A CB  1 -0.109 0.01   0.002  
ATOM   371   C  CG1 . VAL A 1 83  ? -10.643 0.231   1.328   1    105.41 ? 72  VAL A CG1 1 -0.098 0.002  0.003  
ATOM   372   C  CG2 . VAL A 1 83  ? -11.394 2.457   0.397   1    106.6  ? 72  VAL A CG2 1 -0.104 0.023  0.001  
ATOM   373   N  N   . ILE A 1 84  ? -12.689 1.003   -2.447  1    102.54 ? 73  ILE A N   1 -0.116 0.009  -0.006 
ATOM   374   C  CA  . ILE A 1 84  ? -12.273 0.98    -3.847  1    103.59 ? 73  ILE A CA  1 -0.112 0.009  -0.01  
ATOM   375   C  C   . ILE A 1 84  ? -11.732 2.349   -4.221  1    106.41 ? 73  ILE A C   1 -0.108 0.022  -0.011 
ATOM   376   O  O   . ILE A 1 84  ? -12.145 3.377   -3.67   1    109.67 ? 73  ILE A O   1 -0.111 0.031  -0.009 
ATOM   377   C  CB  . ILE A 1 84  ? -13.42  0.584   -4.8    1    94     ? 73  ILE A CB  1 -0.123 0.005  -0.012 
ATOM   378   C  CG1 . ILE A 1 84  ? -14.534 1.631   -4.77   1    90.32  ? 73  ILE A CG1 1 -0.133 0.015  -0.012 
ATOM   379   C  CG2 . ILE A 1 84  ? -13.962 -0.768  -4.412  1    96.15  ? 73  ILE A CG2 1 -0.128 -0.007 -0.011 
ATOM   380   C  CD1 . ILE A 1 84  ? -15.702 1.307   -5.681  1    95.75  ? 73  ILE A CD1 1 -0.144 0.012  -0.014 
ATOM   381   N  N   . THR A 1 85  ? -10.813 2.361   -5.177  1    101.3  ? 74  THR A N   1 -0.099 0.022  -0.013 
ATOM   382   C  CA  . THR A 1 85  ? -10.016 3.546   -5.445  1    107.98 ? 74  THR A CA  1 -0.092 0.032  -0.014 
ATOM   383   C  C   . THR A 1 85  ? -10.106 3.919   -6.921  1    114.9  ? 74  THR A C   1 -0.093 0.036  -0.017 
ATOM   384   O  O   . THR A 1 85  ? -9.983  3.057   -7.798  1    117.83 ? 74  THR A O   1 -0.091 0.028  -0.019 
ATOM   385   C  CB  . THR A 1 85  ? -8.569  3.291   -5.033  1    111.75 ? 74  THR A CB  1 -0.079 0.03   -0.013 
ATOM   386   O  OG1 . THR A 1 85  ? -7.734  4.326   -5.563  1    120.68 ? 74  THR A OG1 1 -0.071 0.04   -0.014 
ATOM   387   C  CG2 . THR A 1 85  ? -8.109  1.912   -5.561  1    116.68 ? 74  THR A CG2 1 -0.074 0.018  -0.014 
ATOM   388   N  N   . THR A 1 86  ? -10.3   5.207   -7.2    1    109.24 ? 75  THR A N   1 -0.094 0.048  -0.018 
ATOM   389   C  CA  . THR A 1 86  ? -10.488 5.623   -8.584  1    111.71 ? 75  THR A CA  1 -0.096 0.052  -0.021 
ATOM   390   C  C   . THR A 1 86  ? -9.249  5.425   -9.452  1    118.89 ? 75  THR A C   1 -0.085 0.05   -0.024 
ATOM   391   O  O   . THR A 1 86  ? -9.3    5.76    -10.644 1    117.21 ? 75  THR A O   1 -0.085 0.053  -0.027 
ATOM   392   C  CB  . THR A 1 86  ? -10.918 7.087   -8.644  1    105.16 ? 75  THR A CB  1 -0.1   0.065  -0.022 
ATOM   393   O  OG1 . THR A 1 86  ? -9.939  7.896   -7.98   1    101.48 ? 75  THR A OG1 1 -0.091 0.072  -0.02  
ATOM   394   C  CG2 . THR A 1 86  ? -12.292 7.276   -8.001  1    100.08 ? 75  THR A CG2 1 -0.113 0.067  -0.02  
ATOM   395   N  N   . GLN A 1 87  ? -8.145  4.901   -8.916  1    119.06 ? 76  GLN A N   1 -0.075 0.045  -0.022 
ATOM   396   C  CA  . GLN A 1 87  ? -6.997  4.644   -9.775  1    123.55 ? 76  GLN A CA  1 -0.064 0.043  -0.024 
ATOM   397   C  C   . GLN A 1 87  ? -7.069  3.296   -10.47  1    124.76 ? 76  GLN A C   1 -0.065 0.03   -0.026 
ATOM   398   O  O   . GLN A 1 87  ? -6.508  3.148   -11.561 1    133.89 ? 76  GLN A O   1 -0.06  0.029  -0.029 
ATOM   399   C  CB  . GLN A 1 87  ? -5.687  4.721   -8.991  1    126.38 ? 76  GLN A CB  1 -0.052 0.043  -0.022 
ATOM   400   C  CG  . GLN A 1 87  ? -5.292  3.436   -8.28   1    127.82 ? 76  GLN A CG  1 -0.048 0.031  -0.021 
ATOM   401   C  CD  . GLN A 1 87  ? -3.78   3.248   -8.228  1    133.96 ? 76  GLN A CD  1 -0.035 0.03   -0.021 
ATOM   402   O  OE1 . GLN A 1 87  ? -3.03   4.189   -7.944  1    132.19 ? 76  GLN A OE1 1 -0.028 0.038  -0.02  
ATOM   403   N  NE2 . GLN A 1 87  ? -3.326  2.031   -8.519  1    133.53 ? 76  GLN A NE2 1 -0.03  0.019  -0.021 
ATOM   404   N  N   . GLU A 1 88  ? -7.754  2.314   -9.884  1    122.09 ? 77  GLU A N   1 -0.071 0.021  -0.025 
ATOM   405   C  CA  . GLU A 1 88  ? -7.681  0.964   -10.431 1    125.77 ? 77  GLU A CA  1 -0.07  0.009  -0.026 
ATOM   406   C  C   . GLU A 1 88  ? -8.571  0.776   -11.654 1    126.18 ? 77  GLU A C   1 -0.079 0.007  -0.029 
ATOM   407   O  O   . GLU A 1 88  ? -8.268  -0.068  -12.506 1    131.71 ? 77  GLU A O   1 -0.076 -0.001 -0.031 
ATOM   408   C  CB  . GLU A 1 88  ? -8.048  -0.058  -9.358  1    129.39 ? 77  GLU A CB  1 -0.074 -0.001 -0.023 
ATOM   409   C  CG  . GLU A 1 88  ? -9.389  0.198   -8.687  1    130.27 ? 77  GLU A CG  1 -0.086 0.002  -0.022 
ATOM   410   C  CD  . GLU A 1 88  ? -10.564 -0.412  -9.44   1    131.64 ? 77  GLU A CD  1 -0.097 -0.004 -0.024 
ATOM   411   O  OE1 . GLU A 1 88  ? -10.338 -1.069  -10.479 1    131.91 ? 77  GLU A OE1 1 -0.095 -0.01  -0.026 
ATOM   412   O  OE2 . GLU A 1 88  ? -11.718 -0.245  -8.983  1    130    ? 77  GLU A OE2 1 -0.107 -0.002 -0.022 
ATOM   413   N  N   . THR A 1 89  ? -9.673  1.523   -11.746 1    125.58 ? 78  THR A N   1 -0.089 0.014  -0.029 
ATOM   414   C  CA  . THR A 1 89  ? -10.576 1.416   -12.889 1    124.47 ? 78  THR A CA  1 -0.097 0.013  -0.032 
ATOM   415   C  C   . THR A 1 89  ? -9.972  2.104   -14.108 1    120.82 ? 78  THR A C   1 -0.091 0.019  -0.035 
ATOM   416   O  O   . THR A 1 89  ? -9.702  3.314   -14.092 1    112.1  ? 78  THR A O   1 -0.089 0.03   -0.035 
ATOM   417   C  CB  . THR A 1 89  ? -11.934 2.028   -12.561 1    120.14 ? 78  THR A CB  1 -0.109 0.019  -0.031 
ATOM   418   O  OG1 . THR A 1 89  ? -11.733 3.296   -11.931 1    120.68 ? 78  THR A OG1 1 -0.108 0.03   -0.03  
ATOM   419   C  CG2 . THR A 1 89  ? -12.717 1.126   -11.635 1    118.5  ? 78  THR A CG2 1 -0.117 0.01   -0.029 
ATOM   420   N  N   . ARG A 1 90  ? -9.76   1.336   -15.165 1    114.4  ? 79  ARG A N   1 -0.089 0.012  -0.038 
ATOM   421   C  CA  . ARG A 1 90  ? -9.221  1.876   -16.397 1    126.77 ? 79  ARG A CA  1 -0.085 0.017  -0.041 
ATOM   422   C  C   . ARG A 1 90  ? -10.378 2.107   -17.368 1    121.2  ? 79  ARG A C   1 -0.095 0.019  -0.043 
ATOM   423   O  O   . ARG A 1 90  ? -11.263 1.252   -17.505 1    117.54 ? 79  ARG A O   1 -0.103 0.011  -0.044 
ATOM   424   C  CB  . ARG A 1 90  ? -8.152  0.931   -16.956 1    133.5  ? 79  ARG A CB  1 -0.075 0.009  -0.042 
ATOM   425   C  CG  . ARG A 1 90  ? -7.25   0.327   -15.838 1    132.9  ? 79  ARG A CG  1 -0.066 0.003  -0.04  
ATOM   426   C  CD  . ARG A 1 90  ? -5.741  0.595   -16.049 1    142.4  ? 79  ARG A CD  1 -0.053 0.005  -0.04  
ATOM   427   N  NE  . ARG A 1 90  ? -4.901  -0.524  -15.622 1    144.34 ? 79  ARG A NE  1 -0.045 -0.005 -0.039 
ATOM   428   C  CZ  . ARG A 1 90  ? -3.572  -0.522  -15.632 1    139.04 ? 79  ARG A CZ  1 -0.033 -0.005 -0.039 
ATOM   429   N  NH1 . ARG A 1 90  ? -2.884  0.552   -15.989 1    129.65 ? 79  ARG A NH1 1 -0.026 0.005  -0.04  
ATOM   430   N  NH2 . ARG A 1 90  ? -2.915  -1.624  -15.271 1    133.36 ? 79  ARG A NH2 1 -0.027 -0.015 -0.038 
ATOM   431   N  N   . LEU A 1 91  ? -10.409 3.285   -17.977 1    108.97 ? 80  LEU A N   1 -0.095 0.03   -0.045 
ATOM   432   C  CA  . LEU A 1 91  ? -11.458 3.631   -18.92  1    117.59 ? 80  LEU A CA  1 -0.105 0.033  -0.047 
ATOM   433   C  C   . LEU A 1 91  ? -11.177 3.02    -20.293 1    116.42 ? 80  LEU A C   1 -0.102 0.028  -0.051 
ATOM   434   O  O   . LEU A 1 91  ? -10.076 2.522   -20.562 1    115.62 ? 80  LEU A O   1 -0.092 0.023  -0.051 
ATOM   435   C  CB  . LEU A 1 91  ? -11.577 5.149   -19.04  1    117.31 ? 80  LEU A CB  1 -0.106 0.047  -0.048 
ATOM   436   C  CG  . LEU A 1 91  ? -11.878 5.997   -17.828 1    103.6  ? 80  LEU A CG  1 -0.109 0.055  -0.045 
ATOM   437   C  CD1 . LEU A 1 91  ? -12.848 5.223   -17.006 1    101.48 ? 80  LEU A CD1 1 -0.118 0.048  -0.042 
ATOM   438   C  CD2 . LEU A 1 91  ? -10.586 6.25    -17.126 1    109.45 ? 80  LEU A CD2 1 -0.097 0.057  -0.043 
ATOM   439   N  N   . PRO A 1 92  ? -12.158 3.047   -21.2   1    108.87 ? 81  PRO A N   1 -0.111 0.028  -0.053 
ATOM   440   C  CA  . PRO A 1 92  ? -11.866 2.65    -22.572 1    110.66 ? 81  PRO A CA  1 -0.109 0.024  -0.056 
ATOM   441   C  C   . PRO A 1 92  ? -10.869 3.632   -23.171 1    114.93 ? 81  PRO A C   1 -0.1   0.033  -0.058 
ATOM   442   O  O   . PRO A 1 92  ? -10.639 4.724   -22.638 1    111.25 ? 81  PRO A O   1 -0.097 0.043  -0.057 
ATOM   443   C  CB  . PRO A 1 92  ? -13.234 2.72    -23.27  1    112.04 ? 81  PRO A CB  1 -0.121 0.025  -0.058 
ATOM   444   C  CG  . PRO A 1 92  ? -14.233 2.759   -22.178 1    108.88 ? 81  PRO A CG  1 -0.13  0.025  -0.055 
ATOM   445   C  CD  . PRO A 1 92  ? -13.565 3.451   -21.052 1    110.03 ? 81  PRO A CD  1 -0.124 0.032  -0.053 
ATOM   446   N  N   . TYR A 1 93  ? -10.246 3.202   -24.275 1    116.1  ? 82  TYR A N   1 -0.094 0.029  -0.061 
ATOM   447   C  CA  . TYR A 1 93  ? -9.212  4.003   -24.925 1    115.32 ? 82  TYR A CA  1 -0.084 0.037  -0.062 
ATOM   448   C  C   . TYR A 1 93  ? -9.699  5.428   -25.222 1    115.58 ? 82  TYR A C   1 -0.089 0.05   -0.063 
ATOM   449   O  O   . TYR A 1 93  ? -9.059  6.404   -24.811 1    111.67 ? 82  TYR A O   1 -0.083 0.059  -0.062 
ATOM   450   C  CB  . TYR A 1 93  ? -8.713  3.293   -26.2   1    116.18 ? 82  TYR A CB  1 -0.08  0.03   -0.065 
ATOM   451   C  CG  . TYR A 1 93  ? -9.582  3.429   -27.438 1    120.7  ? 82  TYR A CG  1 -0.088 0.031  -0.069 
ATOM   452   C  CD1 . TYR A 1 93  ? -10.669 2.577   -27.654 1    120.36 ? 82  TYR A CD1 1 -0.098 0.024  -0.069 
ATOM   453   C  CD2 . TYR A 1 93  ? -9.293  4.388   -28.414 1    124.48 ? 82  TYR A CD2 1 -0.085 0.04   -0.071 
ATOM   454   C  CE1 . TYR A 1 93  ? -11.458 2.689   -28.803 1    119.31 ? 82  TYR A CE1 1 -0.105 0.025  -0.072 
ATOM   455   C  CE2 . TYR A 1 93  ? -10.077 4.508   -29.567 1    122.59 ? 82  TYR A CE2 1 -0.092 0.041  -0.074 
ATOM   456   C  CZ  . TYR A 1 93  ? -11.159 3.658   -29.753 1    121.41 ? 82  TYR A CZ  1 -0.102 0.034  -0.074 
ATOM   457   O  OH  . TYR A 1 93  ? -11.931 3.787   -30.891 1    125.05 ? 82  TYR A OH  1 -0.109 0.035  -0.077 
ATOM   458   N  N   . TYR A 1 94  ? -10.854 5.568   -25.897 1    113.38 ? 83  TYR A N   1 -0.099 0.051  -0.065 
ATOM   459   C  CA  . TYR A 1 94  ? -11.295 6.891   -26.34  1    110.3  ? 83  TYR A CA  1 -0.104 0.063  -0.066 
ATOM   460   C  C   . TYR A 1 94  ? -11.434 7.883   -25.179 1    113.56 ? 83  TYR A C   1 -0.105 0.072  -0.063 
ATOM   461   O  O   . TYR A 1 94  ? -11.15  9.075   -25.352 1    114.82 ? 83  TYR A O   1 -0.102 0.083  -0.063 
ATOM   462   C  CB  . TYR A 1 94  ? -12.603 6.788   -27.14  1    105.36 ? 83  TYR A CB  1 -0.115 0.062  -0.068 
ATOM   463   C  CG  . TYR A 1 94  ? -13.664 5.886   -26.559 1    104.58 ? 83  TYR A CG  1 -0.125 0.054  -0.066 
ATOM   464   C  CD1 . TYR A 1 94  ? -13.677 4.526   -26.829 1    104.15 ? 83  TYR A CD1 1 -0.125 0.041  -0.067 
ATOM   465   C  CD2 . TYR A 1 94  ? -14.664 6.4     -25.748 1    105.8  ? 83  TYR A CD2 1 -0.134 0.059  -0.064 
ATOM   466   C  CE1 . TYR A 1 94  ? -14.654 3.688   -26.286 1    107.04 ? 83  TYR A CE1 1 -0.134 0.034  -0.066 
ATOM   467   C  CE2 . TYR A 1 94  ? -15.645 5.575   -25.193 1    107.59 ? 83  TYR A CE2 1 -0.143 0.051  -0.063 
ATOM   468   C  CZ  . TYR A 1 94  ? -15.638 4.22    -25.465 1    109.24 ? 83  TYR A CZ  1 -0.143 0.039  -0.064 
ATOM   469   O  OH  . TYR A 1 94  ? -16.618 3.416   -24.907 1    105.5  ? 83  TYR A OH  1 -0.152 0.031  -0.062 
ATOM   470   N  N   . TRP A 1 95  ? -11.847 7.426   -23.988 1    110.74 ? 84  TRP A N   1 -0.109 0.068  -0.06  
ATOM   471   C  CA  . TRP A 1 95  ? -11.794 8.314   -22.823 1    110.04 ? 84  TRP A CA  1 -0.108 0.076  -0.057 
ATOM   472   C  C   . TRP A 1 95  ? -10.352 8.702   -22.494 1    110.89 ? 84  TRP A C   1 -0.095 0.08   -0.056 
ATOM   473   O  O   . TRP A 1 95  ? -10.063 9.891   -22.283 1    110.66 ? 84  TRP A O   1 -0.092 0.091  -0.056 
ATOM   474   C  CB  . TRP A 1 95  ? -12.478 7.675   -21.604 1    101.62 ? 84  TRP A CB  1 -0.114 0.07   -0.054 
ATOM   475   C  CG  . TRP A 1 95  ? -13.963 7.786   -21.649 1    93.84  ? 84  TRP A CG  1 -0.128 0.071  -0.054 
ATOM   476   C  CD1 . TRP A 1 95  ? -14.867 6.765   -21.813 1    94.95  ? 84  TRP A CD1 1 -0.136 0.062  -0.054 
ATOM   477   C  CD2 . TRP A 1 95  ? -14.725 8.99    -21.578 1    87.03  ? 84  TRP A CD2 1 -0.135 0.082  -0.054 
ATOM   478   N  NE1 . TRP A 1 95  ? -16.146 7.266   -21.836 1    90.23  ? 84  TRP A NE1 1 -0.148 0.067  -0.055 
ATOM   479   C  CE2 . TRP A 1 95  ? -16.088 8.628   -21.693 1    90.78  ? 84  TRP A CE2 1 -0.147 0.079  -0.054 
ATOM   480   C  CE3 . TRP A 1 95  ? -14.392 10.337  -21.424 1    87.17  ? 84  TRP A CE3 1 -0.132 0.095  -0.053 
ATOM   481   C  CZ2 . TRP A 1 95  ? -17.113 9.568   -21.648 1    89.02  ? 84  TRP A CZ2 1 -0.157 0.088  -0.054 
ATOM   482   C  CZ3 . TRP A 1 95  ? -15.412 11.273  -21.384 1    83.7   ? 84  TRP A CZ3 1 -0.141 0.103  -0.053 
ATOM   483   C  CH2 . TRP A 1 95  ? -16.755 10.883  -21.495 1    88.4   ? 84  TRP A CH2 1 -0.154 0.1    -0.054 
ATOM   484   N  N   . LEU A 1 96  ? -9.431  7.728   -22.46  1    108.68 ? 85  LEU A N   1 -0.086 0.071  -0.056 
ATOM   485   C  CA  . LEU A 1 96  ? -8.032  8.048   -22.168 1    110.01 ? 85  LEU A CA  1 -0.074 0.074  -0.055 
ATOM   486   C  C   . LEU A 1 96  ? -7.452  9.032   -23.191 1    110.56 ? 85  LEU A C   1 -0.068 0.083  -0.058 
ATOM   487   O  O   . LEU A 1 96  ? -6.545  9.81    -22.86  1    102.18 ? 85  LEU A O   1 -0.06  0.09   -0.057 
ATOM   488   C  CB  . LEU A 1 96  ? -7.185  6.762   -22.105 1    112.79 ? 85  LEU A CB  1 -0.066 0.062  -0.055 
ATOM   489   C  CG  . LEU A 1 96  ? -7.143  5.833   -20.873 1    104.23 ? 85  LEU A CG  1 -0.065 0.053  -0.052 
ATOM   490   C  CD1 . LEU A 1 96  ? -8.516  5.549   -20.356 1    116.88 ? 85  LEU A CD1 1 -0.078 0.051  -0.051 
ATOM   491   C  CD2 . LEU A 1 96  ? -6.454  4.492   -21.167 1    104.34 ? 85  LEU A CD2 1 -0.059 0.041  -0.053 
ATOM   492   N  N   . ASP A 1 97  ? -7.978  9.04    -24.43  1    116.02 ? 86  ASP A N   1 -0.073 0.083  -0.061 
ATOM   493   C  CA  . ASP A 1 97  ? -7.453  9.949   -25.454 1    110.72 ? 86  ASP A CA  1 -0.068 0.091  -0.064 
ATOM   494   C  C   . ASP A 1 97  ? -8.05   11.352  -25.352 1    106.73 ? 86  ASP A C   1 -0.074 0.104  -0.063 
ATOM   495   O  O   . ASP A 1 97  ? -7.331  12.342  -25.537 1    103.45 ? 86  ASP A O   1 -0.067 0.113  -0.064 
ATOM   496   C  CB  . ASP A 1 97  ? -7.681  9.362   -26.844 1    113.11 ? 86  ASP A CB  1 -0.07  0.086  -0.067 
ATOM   497   C  CG  . ASP A 1 97  ? -6.957  8.045   -27.046 1    123.52 ? 86  ASP A CG  1 -0.064 0.074  -0.068 
ATOM   498   O  OD1 . ASP A 1 97  ? -7.624  6.982   -26.984 1    124.47 ? 86  ASP A OD1 1 -0.07  0.064  -0.067 
ATOM   499   O  OD2 . ASP A 1 97  ? -5.717  8.092   -27.27  1    123.23 ? 86  ASP A OD2 1 -0.052 0.074  -0.068 
ATOM   500   N  N   . LEU A 1 98  ? -9.353  11.467  -25.052 1    104.75 ? 87  LEU A N   1 -0.086 0.105  -0.063 
ATOM   501   C  CA  . LEU A 1 98  ? -9.912  12.784  -24.736 1    100.46 ? 87  LEU A CA  1 -0.091 0.117  -0.062 
ATOM   502   C  C   . LEU A 1 98  ? -9.155  13.425  -23.584 1    108.64 ? 87  LEU A C   1 -0.084 0.123  -0.059 
ATOM   503   O  O   . LEU A 1 98  ? -8.759  14.595  -23.666 1    103.17 ? 87  LEU A O   1 -0.08  0.134  -0.059 
ATOM   504   C  CB  . LEU A 1 98  ? -11.403 12.691  -24.405 1    99.52  ? 87  LEU A CB  1 -0.104 0.116  -0.061 
ATOM   505   C  CG  . LEU A 1 98  ? -11.943 13.975  -23.753 1    96.21  ? 87  LEU A CG  1 -0.109 0.128  -0.059 
ATOM   506   C  CD1 . LEU A 1 98  ? -11.69  15.222  -24.586 1    94.79  ? 87  LEU A CD1 1 -0.107 0.139  -0.061 
ATOM   507   C  CD2 . LEU A 1 98  ? -13.418 13.847  -23.447 1    95.76  ? 87  LEU A CD2 1 -0.123 0.127  -0.059 
ATOM   508   N  N   . PHE A 1 99  ? -8.943  12.663  -22.496 1    111.61 ? 88  PHE A N   1 -0.082 0.116  -0.056 
ATOM   509   C  CA  . PHE A 1 99  ? -8.081  13.117  -21.403 1    107.19 ? 88  PHE A CA  1 -0.074 0.12   -0.053 
ATOM   510   C  C   . PHE A 1 99  ? -6.743  13.641  -21.936 1    109.68 ? 88  PHE A C   1 -0.062 0.125  -0.055 
ATOM   511   O  O   . PHE A 1 99  ? -6.378  14.803  -21.709 1    105.55 ? 88  PHE A O   1 -0.058 0.136  -0.054 
ATOM   512   C  CB  . PHE A 1 99  ? -7.844  11.974  -20.412 1    107.89 ? 88  PHE A CB  1 -0.072 0.11   -0.051 
ATOM   513   C  CG  . PHE A 1 99  ? -9.1    11.462  -19.73  1    108.73 ? 88  PHE A CG  1 -0.083 0.105  -0.049 
ATOM   514   C  CD1 . PHE A 1 99  ? -10.24  12.251  -19.645 1    102.75 ? 88  PHE A CD1 1 -0.094 0.112  -0.049 
ATOM   515   C  CD2 . PHE A 1 99  ? -9.127  10.188  -19.154 1    105.45 ? 88  PHE A CD2 1 -0.084 0.093  -0.048 
ATOM   516   C  CE1 . PHE A 1 99  ? -11.382 11.783  -19.016 1    101.62 ? 88  PHE A CE1 1 -0.104 0.108  -0.047 
ATOM   517   C  CE2 . PHE A 1 99  ? -10.263 9.715   -18.527 1    104.95 ? 88  PHE A CE2 1 -0.094 0.089  -0.046 
ATOM   518   C  CZ  . PHE A 1 99  ? -11.394 10.517  -18.456 1    104.53 ? 88  PHE A CZ  1 -0.104 0.096  -0.046 
ATOM   519   N  N   . ALA A 1 100 ? -6.019  12.788  -22.679 1    111.75 ? 89  ALA A N   1 -0.055 0.117  -0.057 
ATOM   520   C  CA  . ALA A 1 100 ? -4.675  13.123  -23.15  1    111.24 ? 89  ALA A CA  1 -0.043 0.12   -0.058 
ATOM   521   C  C   . ALA A 1 100 ? -4.67   14.431  -23.935 1    117.47 ? 89  ALA A C   1 -0.043 0.132  -0.06  
ATOM   522   O  O   . ALA A 1 100 ? -3.843  15.319  -23.682 1    114.05 ? 89  ALA A O   1 -0.035 0.14   -0.059 
ATOM   523   C  CB  . ALA A 1 100 ? -4.118  11.972  -23.99  1    97.88  ? 89  ALA A CB  1 -0.038 0.11   -0.06  
ATOM   524   N  N   . ALA A 1 101 ? -5.623  14.58   -24.869 1    113.9  ? 90  ALA A N   1 -0.052 0.134  -0.062 
ATOM   525   C  CA  . ALA A 1 101 ? -5.794  15.833  -25.601 1    106.94 ? 90  ALA A CA  1 -0.053 0.145  -0.064 
ATOM   526   C  C   . ALA A 1 101 ? -5.951  17.045  -24.676 1    116.24 ? 90  ALA A C   1 -0.055 0.156  -0.062 
ATOM   527   O  O   . ALA A 1 101 ? -5.39   18.116  -24.951 1    113.46 ? 90  ALA A O   1 -0.049 0.166  -0.062 
ATOM   528   C  CB  . ALA A 1 101 ? -7.002  15.723  -26.522 1    107.33 ? 90  ALA A CB  1 -0.064 0.144  -0.066 
ATOM   529   N  N   . ILE A 1 102 ? -6.73   16.905  -23.589 1    119.04 ? 91  ILE A N   1 -0.062 0.155  -0.059 
ATOM   530   C  CA  . ILE A 1 102 ? -6.911  18.001  -22.632 1    116.5  ? 91  ILE A CA  1 -0.063 0.165  -0.057 
ATOM   531   C  C   . ILE A 1 102 ? -5.576  18.416  -22.033 1    114.58 ? 91  ILE A C   1 -0.051 0.169  -0.055 
ATOM   532   O  O   . ILE A 1 102 ? -5.364  19.592  -21.708 1    113.41 ? 91  ILE A O   1 -0.049 0.18   -0.054 
ATOM   533   C  CB  . ILE A 1 102 ? -7.909  17.604  -21.521 1    111.85 ? 91  ILE A CB  1 -0.072 0.161  -0.054 
ATOM   534   C  CG1 . ILE A 1 102 ? -9.269  17.259  -22.131 1    108.2  ? 91  ILE A CG1 1 -0.085 0.158  -0.055 
ATOM   535   C  CG2 . ILE A 1 102 ? -8.068  18.734  -20.508 1    108.65 ? 91  ILE A CG2 1 -0.074 0.172  -0.051 
ATOM   536   C  CD1 . ILE A 1 102 ? -10.295 16.802  -21.137 1    104.27 ? 91  ILE A CD1 1 -0.094 0.154  -0.053 
ATOM   537   N  N   . ASP A 1 103 ? -4.646  17.475  -21.906 1    113.57 ? 92  ASP A N   1 -0.043 0.16   -0.055 
ATOM   538   C  CA  . ASP A 1 103 ? -3.409  17.788  -21.215 1    121.16 ? 92  ASP A CA  1 -0.031 0.163  -0.053 
ATOM   539   C  C   . ASP A 1 103 ? -2.457  18.61   -22.082 1    124.06 ? 92  ASP A C   1 -0.023 0.171  -0.055 
ATOM   540   O  O   . ASP A 1 103 ? -1.748  19.482  -21.562 1    122.64 ? 92  ASP A O   1 -0.016 0.179  -0.054 
ATOM   541   C  CB  . ASP A 1 103 ? -2.741  16.498  -20.734 1    122.58 ? 92  ASP A CB  1 -0.025 0.151  -0.052 
ATOM   542   C  CG  . ASP A 1 103 ? -3.624  15.68   -19.784 1    126.06 ? 92  ASP A CG  1 -0.033 0.144  -0.049 
ATOM   543   O  OD1 . ASP A 1 103 ? -3.08   14.755  -19.147 1    131.08 ? 92  ASP A OD1 1 -0.028 0.135  -0.048 
ATOM   544   O  OD2 . ASP A 1 103 ? -4.856  15.94   -19.697 1    128.25 ? 92  ASP A OD2 1 -0.045 0.146  -0.049 
ATOM   545   N  N   . GLU A 1 104 ? -2.42   18.366  -23.399 1    119.45 ? 93  GLU A N   1 -0.022 0.168  -0.058 
ATOM   546   C  CA  . GLU A 1 104 ? -1.495  19.127  -24.232 1    124.41 ? 93  GLU A CA  1 -0.014 0.175  -0.061 
ATOM   547   C  C   . GLU A 1 104 ? -2.056  20.476  -24.688 1    124.57 ? 93  GLU A C   1 -0.019 0.188  -0.062 
ATOM   548   O  O   . GLU A 1 104 ? -1.314  21.274  -25.278 1    123.88 ? 93  GLU A O   1 -0.012 0.195  -0.063 
ATOM   549   C  CB  . GLU A 1 104 ? -1.05   18.303  -25.449 1    124.09 ? 93  GLU A CB  1 -0.01  0.168  -0.064 
ATOM   550   C  CG  . GLU A 1 104 ? -2.159  17.821  -26.362 1    125.75 ? 93  GLU A CG  1 -0.02  0.163  -0.066 
ATOM   551   C  CD  . GLU A 1 104 ? -2.219  16.31   -26.41  1    128.98 ? 93  GLU A CD  1 -0.02  0.149  -0.066 
ATOM   552   O  OE1 . GLU A 1 104 ? -1.849  15.704  -25.37  1    131.6  ? 93  GLU A OE1 1 -0.017 0.144  -0.063 
ATOM   553   O  OE2 . GLU A 1 104 ? -2.614  15.744  -27.469 1    115.06 ? 93  GLU A OE2 1 -0.024 0.144  -0.069 
ATOM   554   N  N   . GLY A 1 105 ? -3.329  20.765  -24.428 1    123.3  ? 94  GLY A N   1 -0.031 0.19   -0.061 
ATOM   555   C  CA  . GLY A 1 105 ? -3.867  22.089  -24.675 1    122.26 ? 94  GLY A CA  1 -0.035 0.202  -0.062 
ATOM   556   C  C   . GLY A 1 105 ? -4.639  22.273  -25.967 1    117.8  ? 94  GLY A C   1 -0.043 0.204  -0.065 
ATOM   557   O  O   . GLY A 1 105 ? -5.161  23.37   -26.202 1    117.3  ? 94  GLY A O   1 -0.047 0.214  -0.065 
ATOM   558   N  N   . ASP A 1 106 ? -4.736  21.25   -26.81  1    108.95 ? 95  ASP A N   1 -0.043 0.195  -0.067 
ATOM   559   C  CA  . ASP A 1 106 ? -5.527  21.405  -28.022 1    119.85 ? 95  ASP A CA  1 -0.051 0.196  -0.07  
ATOM   560   C  C   . ASP A 1 106 ? -7.007  21.476  -27.666 1    112.79 ? 95  ASP A C   1 -0.064 0.197  -0.069 
ATOM   561   O  O   . ASP A 1 106 ? -7.667  20.44   -27.542 1    110.16 ? 95  ASP A O   1 -0.07  0.187  -0.069 
ATOM   562   C  CB  . ASP A 1 106 ? -5.252  20.259  -29.008 1    120.38 ? 95  ASP A CB  1 -0.048 0.186  -0.072 
ATOM   563   C  CG  . ASP A 1 106 ? -4.251  20.638  -30.103 1    126.81 ? 95  ASP A CG  1 -0.039 0.189  -0.075 
ATOM   564   O  OD1 . ASP A 1 106 ? -3.58   21.697  -29.995 1    128.49 ? 95  ASP A OD1 1 -0.033 0.199  -0.075 
ATOM   565   O  OD2 . ASP A 1 106 ? -4.134  19.865  -31.083 1    128.81 ? 95  ASP A OD2 1 -0.038 0.182  -0.078 
ATOM   566   N  N   . THR A 1 107 ? -7.537  22.688  -27.482 1    110.94 ? 96  THR A N   1 -0.069 0.208  -0.069 
ATOM   567   C  CA  . THR A 1 107 ? -8.973  22.817  -27.238 1    113.05 ? 96  THR A CA  1 -0.082 0.209  -0.068 
ATOM   568   C  C   . THR A 1 107 ? -9.815  22.346  -28.422 1    113.05 ? 96  THR A C   1 -0.09  0.205  -0.071 
ATOM   569   O  O   . THR A 1 107 ? -10.834 21.672  -28.185 1    108.68 ? 96  THR A O   1 -0.099 0.199  -0.07  
ATOM   570   C  CB  . THR A 1 107 ? -9.325  24.263  -26.844 1    114    ? 96  THR A CB  1 -0.085 0.222  -0.067 
ATOM   571   O  OG1 . THR A 1 107 ? -8.516  24.675  -25.734 1    120.39 ? 96  THR A OG1 1 -0.078 0.226  -0.064 
ATOM   572   C  CG2 . THR A 1 107 ? -10.79  24.366  -26.427 1    112.05 ? 96  THR A CG2 1 -0.099 0.223  -0.066 
ATOM   573   N  N   . PRO A 1 108 ? -9.466  22.63   -29.686 1    112.78 ? 97  PRO A N   1 -0.087 0.207  -0.074 
ATOM   574   C  CA  . PRO A 1 108 ? -10.235 22.025  -30.793 1    108.07 ? 97  PRO A CA  1 -0.094 0.202  -0.077 
ATOM   575   C  C   . PRO A 1 108 ? -10.066 20.514  -30.918 1    105.61 ? 97  PRO A C   1 -0.092 0.188  -0.077 
ATOM   576   O  O   . PRO A 1 108 ? -11.02  19.839  -31.33  1    103.75 ? 97  PRO A O   1 -0.101 0.182  -0.078 
ATOM   577   C  CB  . PRO A 1 108 ? -9.709  22.755  -32.038 1    116.25 ? 97  PRO A CB  1 -0.089 0.209  -0.08  
ATOM   578   C  CG  . PRO A 1 108 ? -9.13   24.032  -31.518 1    124.85 ? 97  PRO A CG  1 -0.084 0.22   -0.079 
ATOM   579   C  CD  . PRO A 1 108 ? -8.567  23.698  -30.161 1    111.7  ? 97  PRO A CD  1 -0.079 0.217  -0.075 
ATOM   580   N  N   . LYS A 1 109 ? -8.894  19.954  -30.591 1    104.05 ? 98  LYS A N   1 -0.082 0.183  -0.076 
ATOM   581   C  CA  . LYS A 1 109 ? -8.753  18.496  -30.616 1    106.83 ? 98  LYS A CA  1 -0.08  0.169  -0.076 
ATOM   582   C  C   . LYS A 1 109 ? -9.599  17.83   -29.54  1    105.45 ? 98  LYS A C   1 -0.088 0.163  -0.074 
ATOM   583   O  O   . LYS A 1 109 ? -10.224 16.787  -29.784 1    95.9   ? 98  LYS A O   1 -0.094 0.154  -0.074 
ATOM   584   C  CB  . LYS A 1 109 ? -7.294  18.089  -30.437 1    109.17 ? 98  LYS A CB  1 -0.067 0.166  -0.076 
ATOM   585   C  CG  . LYS A 1 109 ? -7.104  16.59   -30.243 1    105.82 ? 98  LYS A CG  1 -0.065 0.152  -0.076 
ATOM   586   C  CD  . LYS A 1 109 ? -5.64   16.24   -30.085 1    112.06 ? 98  LYS A CD  1 -0.052 0.149  -0.075 
ATOM   587   C  CE  . LYS A 1 109 ? -5.402  14.76   -30.342 1    116.59 ? 98  LYS A CE  1 -0.05  0.135  -0.076 
ATOM   588   N  NZ  . LYS A 1 109 ? -3.945  14.484  -30.552 1    128.36 ? 98  LYS A NZ  1 -0.036 0.133  -0.076 
ATOM   589   N  N   . ALA A 1 110 ? -9.583  18.39   -28.325 1    111.57 ? 99  ALA A N   1 -0.088 0.169  -0.071 
ATOM   590   C  CA  . ALA A 1 110 ? -10.44  17.879  -27.262 1    109.69 ? 99  ALA A CA  1 -0.096 0.164  -0.068 
ATOM   591   C  C   . ALA A 1 110 ? -11.902 18.053  -27.639 1    108.21 ? 99  ALA A C   1 -0.109 0.165  -0.069 
ATOM   592   O  O   . ALA A 1 110 ? -12.692 17.1    -27.571 1    108.16 ? 99  ALA A O   1 -0.116 0.157  -0.069 
ATOM   593   C  CB  . ALA A 1 110 ? -10.129 18.584  -25.938 1    107.51 ? 99  ALA A CB  1 -0.093 0.17   -0.065 
ATOM   594   N  N   . HIS A 1 111 ? -12.27  19.261  -28.074 1    100.62 ? 100 HIS A N   1 -0.112 0.177  -0.07  
ATOM   595   C  CA  . HIS A 1 111 ? -13.652 19.516  -28.448 1    104.23 ? 100 HIS A CA  1 -0.125 0.179  -0.071 
ATOM   596   C  C   . HIS A 1 111 ? -14.133 18.507  -29.484 1    105.3  ? 100 HIS A C   1 -0.13  0.17   -0.074 
ATOM   597   O  O   . HIS A 1 111 ? -15.237 17.957  -29.373 1    101.42 ? 100 HIS A O   1 -0.14  0.165  -0.073 
ATOM   598   C  CB  . HIS A 1 111 ? -13.783 20.95   -28.954 1    108.34 ? 100 HIS A CB  1 -0.126 0.192  -0.072 
ATOM   599   C  CG  . HIS A 1 111 ? -14.103 21.941  -27.875 1    109.69 ? 100 HIS A CG  1 -0.129 0.201  -0.07  
ATOM   600   N  ND1 . HIS A 1 111 ? -14.345 23.275  -28.131 1    115.43 ? 100 HIS A ND1 1 -0.131 0.213  -0.07  
ATOM   601   C  CD2 . HIS A 1 111 ? -14.254 21.785  -26.539 1    111.85 ? 100 HIS A CD2 1 -0.131 0.2    -0.066 
ATOM   602   C  CE1 . HIS A 1 111 ? -14.623 23.898  -27     1    115.45 ? 100 HIS A CE1 1 -0.134 0.219  -0.067 
ATOM   603   N  NE2 . HIS A 1 111 ? -14.579 23.015  -26.02  1    116.08 ? 100 HIS A NE2 1 -0.134 0.211  -0.065 
ATOM   604   N  N   . ALA A 1 112 ? -13.287 18.21   -30.47  1    110.08 ? 101 ALA A N   1 -0.122 0.167  -0.076 
ATOM   605   C  CA  . ALA A 1 112 ? -13.659 17.258  -31.51  1    107.84 ? 101 ALA A CA  1 -0.125 0.158  -0.079 
ATOM   606   C  C   . ALA A 1 112 ? -13.667 15.836  -30.972 1    107.85 ? 101 ALA A C   1 -0.125 0.145  -0.077 
ATOM   607   O  O   . ALA A 1 112 ? -14.63  15.082  -31.185 1    101.35 ? 101 ALA A O   1 -0.134 0.138  -0.078 
ATOM   608   C  CB  . ALA A 1 112 ? -12.69  17.381  -32.677 1    104.81 ? 101 ALA A CB  1 -0.116 0.159  -0.082 
ATOM   609   N  N   . LEU A 1 113 ? -12.592 15.456  -30.265 1    107.65 ? 102 LEU A N   1 -0.115 0.142  -0.076 
ATOM   610   C  CA  . LEU A 1 113 ? -12.434 14.083  -29.8   1    102.61 ? 102 LEU A CA  1 -0.114 0.129  -0.074 
ATOM   611   C  C   . LEU A 1 113 ? -13.615 13.668  -28.938 1    105.27 ? 102 LEU A C   1 -0.125 0.125  -0.072 
ATOM   612   O  O   . LEU A 1 113 ? -14.12  12.54   -29.057 1    102.04 ? 102 LEU A O   1 -0.129 0.115  -0.073 
ATOM   613   C  CB  . LEU A 1 113 ? -11.118 13.953  -29.033 1    98.35  ? 102 LEU A CB  1 -0.102 0.128  -0.072 
ATOM   614   C  CG  . LEU A 1 113 ? -9.978  13.227  -29.743 1    106.47 ? 102 LEU A CG  1 -0.091 0.121  -0.074 
ATOM   615   C  CD1 . LEU A 1 113 ? -8.649  13.361  -28.998 1    98.73  ? 102 LEU A CD1 1 -0.079 0.122  -0.072 
ATOM   616   C  CD2 . LEU A 1 113 ? -10.355 11.764  -29.886 1    108.57 ? 102 LEU A CD2 1 -0.095 0.108  -0.075 
ATOM   617   N  N   . PHE A 1 114 ? -14.084 14.592  -28.087 1    103.52 ? 103 PHE A N   1 -0.129 0.134  -0.07  
ATOM   618   C  CA  . PHE A 1 114 ? -15.236 14.345  -27.228 1    99.73  ? 103 PHE A CA  1 -0.14  0.131  -0.068 
ATOM   619   C  C   . PHE A 1 114 ? -16.519 14.237  -28.053 1    96.58  ? 103 PHE A C   1 -0.151 0.13   -0.07  
ATOM   620   O  O   . PHE A 1 114 ? -17.299 13.293  -27.877 1    93.16  ? 103 PHE A O   1 -0.159 0.122  -0.07  
ATOM   621   C  CB  . PHE A 1 114 ? -15.334 15.446  -26.145 1    98.99  ? 103 PHE A CB  1 -0.141 0.142  -0.065 
ATOM   622   C  CG  . PHE A 1 114 ? -16.711 15.583  -25.54  1    96.36  ? 103 PHE A CG  1 -0.153 0.143  -0.064 
ATOM   623   C  CD1 . PHE A 1 114 ? -17.239 14.569  -24.75  1    98.59  ? 103 PHE A CD1 1 -0.158 0.134  -0.062 
ATOM   624   C  CD2 . PHE A 1 114 ? -17.492 16.705  -25.792 1    94.47  ? 103 PHE A CD2 1 -0.16  0.153  -0.064 
ATOM   625   C  CE1 . PHE A 1 114 ? -18.515 14.665  -24.238 1    99.08  ? 103 PHE A CE1 1 -0.17  0.134  -0.061 
ATOM   626   C  CE2 . PHE A 1 114 ? -18.78  16.807  -25.278 1    90.19  ? 103 PHE A CE2 1 -0.172 0.154  -0.063 
ATOM   627   C  CZ  . PHE A 1 114 ? -19.292 15.789  -24.517 1    96.1   ? 103 PHE A CZ  1 -0.177 0.145  -0.061 
ATOM   628   N  N   . HIS A 1 115 ? -16.739 15.173  -28.987 1    102.1  ? 104 HIS A N   1 -0.153 0.139  -0.072 
ATOM   629   C  CA  . HIS A 1 115 ? -17.913 15.103  -29.865 1    108.04 ? 104 HIS A CA  1 -0.164 0.138  -0.075 
ATOM   630   C  C   . HIS A 1 115 ? -18.08  13.725  -30.503 1    105.92 ? 104 HIS A C   1 -0.166 0.126  -0.076 
ATOM   631   O  O   . HIS A 1 115 ? -19.21  13.238  -30.662 1    100.49 ? 104 HIS A O   1 -0.176 0.121  -0.077 
ATOM   632   C  CB  . HIS A 1 115 ? -17.827 16.163  -30.965 1    109.98 ? 104 HIS A CB  1 -0.163 0.148  -0.077 
ATOM   633   C  CG  . HIS A 1 115 ? -19.067 16.258  -31.803 1    113.53 ? 104 HIS A CG  1 -0.175 0.149  -0.079 
ATOM   634   N  ND1 . HIS A 1 115 ? -19.426 15.29   -32.718 1    118.05 ? 104 HIS A ND1 1 -0.178 0.14   -0.082 
ATOM   635   C  CD2 . HIS A 1 115 ? -20.032 17.208  -31.864 1    116.67 ? 104 HIS A CD2 1 -0.184 0.158  -0.08  
ATOM   636   C  CE1 . HIS A 1 115 ? -20.558 15.639  -33.306 1    114.41 ? 104 HIS A CE1 1 -0.188 0.143  -0.083 
ATOM   637   N  NE2 . HIS A 1 115 ? -20.947 16.798  -32.804 1    118.01 ? 104 HIS A NE2 1 -0.192 0.154  -0.082 
ATOM   638   N  N   . LEU A 1 116 ? -16.965 13.08   -30.863 1    101.58 ? 105 LEU A N   1 -0.155 0.12   -0.077 
ATOM   639   C  CA  . LEU A 1 116 ? -16.962 11.803  -31.565 1    103.44 ? 105 LEU A CA  1 -0.155 0.108  -0.079 
ATOM   640   C  C   . LEU A 1 116 ? -16.924 10.575  -30.64  1    108.26 ? 105 LEU A C   1 -0.155 0.097  -0.077 
ATOM   641   O  O   . LEU A 1 116 ? -16.759 9.451   -31.134 1    111.04 ? 105 LEU A O   1 -0.154 0.087  -0.078 
ATOM   642   C  CB  . LEU A 1 116 ? -15.774 11.748  -32.529 1    106.09 ? 105 LEU A CB  1 -0.145 0.108  -0.081 
ATOM   643   C  CG  . LEU A 1 116 ? -15.597 12.824  -33.606 1    111.77 ? 105 LEU A CG  1 -0.143 0.118  -0.084 
ATOM   644   C  CD1 . LEU A 1 116 ? -14.294 12.548  -34.346 1    108.28 ? 105 LEU A CD1 1 -0.131 0.115  -0.086 
ATOM   645   C  CD2 . LEU A 1 116 ? -16.789 12.9    -34.578 1    98.91  ? 105 LEU A CD2 1 -0.154 0.118  -0.086 
ATOM   646   N  N   . LEU A 1 117 ? -17.074 10.743  -29.33  1    103.71 ? 106 LEU A N   1 -0.156 0.098  -0.073 
ATOM   647   C  CA  . LEU A 1 117 ? -17.145 9.572   -28.469 1    100.98 ? 106 LEU A CA  1 -0.157 0.088  -0.071 
ATOM   648   C  C   . LEU A 1 117 ? -18.391 8.741   -28.783 1    96.89  ? 106 LEU A C   1 -0.169 0.08   -0.072 
ATOM   649   O  O   . LEU A 1 117 ? -19.427 9.285   -29.176 1    100.26 ? 106 LEU A O   1 -0.178 0.085  -0.073 
ATOM   650   C  CB  . LEU A 1 117 ? -17.168 9.983   -27.004 1    103.91 ? 106 LEU A CB  1 -0.157 0.091  -0.067 
ATOM   651   C  CG  . LEU A 1 117 ? -15.964 10.74   -26.466 1    105.41 ? 106 LEU A CG  1 -0.146 0.098  -0.066 
ATOM   652   C  CD1 . LEU A 1 117 ? -16.061 10.857  -24.952 1    96.37  ? 106 LEU A CD1 1 -0.147 0.099  -0.062 
ATOM   653   C  CD2 . LEU A 1 117 ? -14.675 10.045  -26.895 1    108.36 ? 106 LEU A CD2 1 -0.134 0.092  -0.067 
ATOM   654   N  N   . PRO A 1 118 ? -18.319 7.424   -28.6   1    95.23  ? 107 PRO A N   1 -0.168 0.068  -0.071 
ATOM   655   C  CA  . PRO A 1 118 ? -19.486 6.566   -28.867 1    102.49 ? 107 PRO A CA  1 -0.179 0.06   -0.072 
ATOM   656   C  C   . PRO A 1 118 ? -20.703 6.962   -28.038 1    107.99 ? 107 PRO A C   1 -0.19  0.064  -0.07  
ATOM   657   O  O   . PRO A 1 118 ? -20.649 7.023   -26.809 1    110.53 ? 107 PRO A O   1 -0.189 0.064  -0.067 
ATOM   658   C  CB  . PRO A 1 118 ? -18.994 5.163   -28.49  1    101.54 ? 107 PRO A CB  1 -0.174 0.047  -0.071 
ATOM   659   C  CG  . PRO A 1 118 ? -17.521 5.241   -28.496 1    101.63 ? 107 PRO A CG  1 -0.161 0.048  -0.071 
ATOM   660   C  CD  . PRO A 1 118 ? -17.131 6.655   -28.202 1    102.91 ? 107 PRO A CD  1 -0.157 0.061  -0.07  
ATOM   661   N  N   . GLN A 1 119 ? -21.82  7.19    -28.733 1    113.59 ? 108 GLN A N   1 -0.2   0.066  -0.072 
ATOM   662   C  CA  . GLN A 1 119 ? -23.088 7.568   -28.116 1    116.74 ? 108 GLN A CA  1 -0.212 0.069  -0.07  
ATOM   663   C  C   . GLN A 1 119 ? -23.644 6.509   -27.166 1    115.62 ? 108 GLN A C   1 -0.217 0.06   -0.068 
ATOM   664   O  O   . GLN A 1 119 ? -24.661 6.77    -26.508 1    115    ? 108 GLN A O   1 -0.226 0.062  -0.066 
ATOM   665   C  CB  . GLN A 1 119 ? -24.128 7.844   -29.209 1    118.04 ? 108 GLN A CB  1 -0.221 0.072  -0.073 
ATOM   666   C  CG  . GLN A 1 119 ? -24.887 6.586   -29.637 1    126.24 ? 108 GLN A CG  1 -0.228 0.06   -0.074 
ATOM   667   C  CD  . GLN A 1 119 ? -25.697 6.775   -30.913 1    138.61 ? 108 GLN A CD  1 -0.235 0.062  -0.077 
ATOM   668   O  OE1 . GLN A 1 119 ? -26.161 5.8     -31.524 1    139.81 ? 108 GLN A OE1 1 -0.24  0.053  -0.079 
ATOM   669   N  NE2 . GLN A 1 119 ? -25.871 8.033   -31.324 1    137.52 ? 108 GLN A NE2 1 -0.237 0.074  -0.078 
ATOM   670   N  N   . ASP A 1 120 ? -23.032 5.326   -27.088 1    112.63 ? 109 ASP A N   1 -0.211 0.049  -0.068 
ATOM   671   C  CA  . ASP A 1 120 ? -23.544 4.239   -26.257 1    116.76 ? 109 ASP A CA  1 -0.216 0.039  -0.066 
ATOM   672   C  C   . ASP A 1 120 ? -22.552 3.772   -25.202 1    111.53 ? 109 ASP A C   1 -0.207 0.035  -0.063 
ATOM   673   O  O   . ASP A 1 120 ? -22.805 2.745   -24.563 1    108.47 ? 109 ASP A O   1 -0.209 0.025  -0.061 
ATOM   674   C  CB  . ASP A 1 120 ? -23.935 3.043   -27.128 1    126.64 ? 109 ASP A CB  1 -0.219 0.028  -0.068 
ATOM   675   C  CG  . ASP A 1 120 ? -22.781 2.564   -27.999 1    121.88 ? 109 ASP A CG  1 -0.209 0.023  -0.07  
ATOM   676   O  OD1 . ASP A 1 120 ? -22.17  3.429   -28.656 1    127.28 ? 109 ASP A OD1 1 -0.203 0.031  -0.072 
ATOM   677   O  OD2 . ASP A 1 120 ? -22.468 1.346   -28.01  1    114.54 ? 109 ASP A OD2 1 -0.206 0.012  -0.07  
ATOM   678   N  N   . ASP A 1 121 ? -21.412 4.456   -25.053 1    111.76 ? 110 ASP A N   1 -0.196 0.041  -0.063 
ATOM   679   C  CA  . ASP A 1 121 ? -20.501 4.201   -23.942 1    106.86 ? 110 ASP A CA  1 -0.188 0.038  -0.06  
ATOM   680   C  C   . ASP A 1 121 ? -21.222 4.478   -22.619 1    110.03 ? 110 ASP A C   1 -0.194 0.041  -0.056 
ATOM   681   O  O   . ASP A 1 121 ? -22.015 5.419   -22.513 1    109.26 ? 110 ASP A O   1 -0.202 0.05   -0.056 
ATOM   682   C  CB  . ASP A 1 121 ? -19.24  5.07    -24.106 1    100.54 ? 110 ASP A CB  1 -0.176 0.046  -0.06  
ATOM   683   C  CG  . ASP A 1 121 ? -18.469 5.283   -22.787 1    112.18 ? 110 ASP A CG  1 -0.169 0.048  -0.057 
ATOM   684   O  OD1 . ASP A 1 121 ? -17.663 4.391   -22.411 1    114.04 ? 110 ASP A OD1 1 -0.162 0.04   -0.056 
ATOM   685   O  OD2 . ASP A 1 121 ? -18.651 6.352   -22.133 1    102.5  ? 110 ASP A OD2 1 -0.171 0.058  -0.055 
ATOM   686   N  N   . ILE A 1 122 ? -20.966 3.63    -21.615 1    105.63 ? 111 ILE A N   1 -0.192 0.033  -0.054 
ATOM   687   C  CA  . ILE A 1 122 ? -21.741 3.675   -20.371 1    110.14 ? 111 ILE A CA  1 -0.199 0.034  -0.051 
ATOM   688   C  C   . ILE A 1 122 ? -21.669 5.058   -19.721 1    101.96 ? 111 ILE A C   1 -0.199 0.046  -0.049 
ATOM   689   O  O   . ILE A 1 122 ? -22.7   5.646   -19.36  1    96.6   ? 111 ILE A O   1 -0.208 0.052  -0.048 
ATOM   690   C  CB  . ILE A 1 122 ? -21.268 2.574   -19.402 1    112.37 ? 111 ILE A CB  1 -0.195 0.024  -0.048 
ATOM   691   C  CG1 . ILE A 1 122 ? -21.021 1.253   -20.156 1    114.52 ? 111 ILE A CG1 1 -0.193 0.011  -0.05  
ATOM   692   C  CG2 . ILE A 1 122 ? -22.288 2.382   -18.294 1    106.89 ? 111 ILE A CG2 1 -0.204 0.022  -0.046 
ATOM   693   C  CD1 . ILE A 1 122 ? -22.237 0.358   -20.283 1    106.08 ? 111 ILE A CD1 1 -0.204 0.003  -0.051 
ATOM   694   N  N   . ILE A 1 123 ? -20.451 5.593   -19.563 1    98.08  ? 112 ILE A N   1 -0.187 0.051  -0.049 
ATOM   695   C  CA  . ILE A 1 123 ? -20.268 6.926   -18.975 1    97.48  ? 112 ILE A CA  1 -0.186 0.063  -0.047 
ATOM   696   C  C   . ILE A 1 123 ? -21.053 7.971   -19.758 1    101.56 ? 112 ILE A C   1 -0.193 0.073  -0.049 
ATOM   697   O  O   . ILE A 1 123 ? -21.866 8.719   -19.202 1    96.67  ? 112 ILE A O   1 -0.2   0.08   -0.048 
ATOM   698   C  CB  . ILE A 1 123 ? -18.778 7.323   -18.941 1    94.63  ? 112 ILE A CB  1 -0.172 0.067  -0.047 
ATOM   699   C  CG1 . ILE A 1 123 ? -17.888 6.302   -18.217 1    97.41  ? 112 ILE A CG1 1 -0.164 0.058  -0.045 
ATOM   700   C  CG2 . ILE A 1 123 ? -18.64  8.738   -18.365 1    84.96  ? 112 ILE A CG2 1 -0.171 0.08   -0.046 
ATOM   701   C  CD1 . ILE A 1 123 ? -16.37  6.552   -18.425 1    87.87  ? 112 ILE A CD1 1 -0.15  0.06   -0.046 
ATOM   702   N  N   . LEU A 1 124 ? -20.767 8.079   -21.06  1    103.38 ? 113 LEU A N   1 -0.19  0.074  -0.053 
ATOM   703   C  CA  . LEU A 1 124 ? -21.176 9.258   -21.817 1    99.86  ? 113 LEU A CA  1 -0.194 0.085  -0.054 
ATOM   704   C  C   . LEU A 1 124 ? -22.689 9.328   -21.956 1    100.78 ? 113 LEU A C   1 -0.208 0.085  -0.055 
ATOM   705   O  O   . LEU A 1 124 ? -23.289 10.401  -21.804 1    95.7   ? 113 LEU A O   1 -0.213 0.095  -0.054 
ATOM   706   C  CB  . LEU A 1 124 ? -20.508 9.258   -23.187 1    98.62  ? 113 LEU A CB  1 -0.188 0.085  -0.058 
ATOM   707   C  CG  . LEU A 1 124 ? -21.108 10.249  -24.175 1    102.25 ? 113 LEU A CG  1 -0.193 0.094  -0.06  
ATOM   708   C  CD1 . LEU A 1 124 ? -19.993 10.852  -24.987 1    101.67 ? 113 LEU A CD1 1 -0.183 0.099  -0.062 
ATOM   709   C  CD2 . LEU A 1 124 ? -22.108 9.558   -25.096 1    104.61 ? 113 LEU A CD2 1 -0.203 0.088  -0.063 
ATOM   710   N  N   . ARG A 1 125 ? -23.313 8.199   -22.286 1    105.25 ? 114 ARG A N   1 -0.214 0.075  -0.056 
ATOM   711   C  CA  . ARG A 1 125 ? -24.764 8.16    -22.398 1    102.94 ? 114 ARG A CA  1 -0.227 0.075  -0.056 
ATOM   712   C  C   . ARG A 1 125 ? -25.411 8.73    -21.139 1    101.46 ? 114 ARG A C   1 -0.233 0.08   -0.053 
ATOM   713   O  O   . ARG A 1 125 ? -26.312 9.574   -21.218 1    102.89 ? 114 ARG A O   1 -0.241 0.088  -0.053 
ATOM   714   C  CB  . ARG A 1 125 ? -25.2   6.722   -22.687 1    99.75  ? 114 ARG A CB  1 -0.231 0.062  -0.057 
ATOM   715   C  CG  . ARG A 1 125 ? -26.541 6.32    -22.165 1    98.05  ? 114 ARG A CG  1 -0.243 0.058  -0.055 
ATOM   716   C  CD  . ARG A 1 125 ? -26.746 4.835   -22.406 1    103.27 ? 114 ARG A CD  1 -0.245 0.044  -0.056 
ATOM   717   N  NE  . ARG A 1 125 ? -25.907 3.957   -21.596 1    97.8   ? 114 ARG A NE  1 -0.237 0.036  -0.054 
ATOM   718   C  CZ  . ARG A 1 125 ? -26.252 2.728   -21.23  1    104.59 ? 114 ARG A CZ  1 -0.241 0.025  -0.053 
ATOM   719   N  NH1 . ARG A 1 125 ? -27.433 2.219   -21.536 1    103.78 ? 114 ARG A NH1 1 -0.251 0.02   -0.054 
ATOM   720   N  NH2 . ARG A 1 125 ? -25.396 1.995   -20.523 1    114.81 ? 114 ARG A NH2 1 -0.233 0.018  -0.051 
ATOM   721   N  N   . ALA A 1 126 ? -24.911 8.331   -19.966 1    103.01 ? 115 ALA A N   1 -0.228 0.076  -0.05  
ATOM   722   C  CA  . ALA A 1 126 ? -25.418 8.891   -18.713 1    100.16 ? 115 ALA A CA  1 -0.233 0.081  -0.047 
ATOM   723   C  C   . ALA A 1 126 ? -24.976 10.344  -18.532 1    95.54  ? 115 ALA A C   1 -0.229 0.095  -0.046 
ATOM   724   O  O   . ALA A 1 126 ? -25.775 11.197  -18.127 1    93.17  ? 115 ALA A O   1 -0.236 0.103  -0.045 
ATOM   725   C  CB  . ALA A 1 126 ? -24.956 8.03    -17.54  1    88.3   ? 115 ALA A CB  1 -0.229 0.074  -0.044 
ATOM   726   N  N   . LEU A 1 127 ? -23.716 10.646  -18.858 1    92.29  ? 116 LEU A N   1 -0.217 0.098  -0.047 
ATOM   727   C  CA  . LEU A 1 127 ? -23.201 12.004  -18.703 1    87.79  ? 116 LEU A CA  1 -0.213 0.11   -0.047 
ATOM   728   C  C   . LEU A 1 127 ? -24.05  13.017  -19.478 1    95.88  ? 116 LEU A C   1 -0.22  0.119  -0.049 
ATOM   729   O  O   . LEU A 1 127 ? -24.508 14.02   -18.918 1    97.13  ? 116 LEU A O   1 -0.225 0.128  -0.047 
ATOM   730   C  CB  . LEU A 1 127 ? -21.732 12.036  -19.146 1    86.34  ? 116 LEU A CB  1 -0.199 0.11   -0.048 
ATOM   731   C  CG  . LEU A 1 127 ? -20.857 13.281  -19.015 1    84.84  ? 116 LEU A CG  1 -0.191 0.122  -0.047 
ATOM   732   C  CD1 . LEU A 1 127 ? -21.144 14.192  -20.113 1    87.62  ? 116 LEU A CD1 1 -0.194 0.13   -0.05  
ATOM   733   C  CD2 . LEU A 1 127 ? -21.102 14.009  -17.695 1    94.5   ? 116 LEU A CD2 1 -0.193 0.128  -0.044 
ATOM   734   N  N   . ARG A 1 128 ? -24.287 12.768  -20.767 1    100.11 ? 117 ARG A N   1 -0.223 0.117  -0.052 
ATOM   735   C  CA  . ARG A 1 128 ? -25.025 13.732  -21.573 1    102.15 ? 117 ARG A CA  1 -0.229 0.126  -0.054 
ATOM   736   C  C   . ARG A 1 128 ? -26.533 13.54   -21.492 1    99.31  ? 117 ARG A C   1 -0.243 0.124  -0.054 
ATOM   737   O  O   . ARG A 1 128 ? -27.276 14.331  -22.089 1    99.1   ? 117 ARG A O   1 -0.25  0.131  -0.055 
ATOM   738   C  CB  . ARG A 1 128 ? -24.57  13.716  -23.049 1    100.87 ? 117 ARG A CB  1 -0.225 0.126  -0.058 
ATOM   739   C  CG  . ARG A 1 128 ? -24.653 15.136  -23.651 1    106.34 ? 117 ARG A CG  1 -0.226 0.139  -0.059 
ATOM   740   C  CD  . ARG A 1 128 ? -24.003 15.383  -25.026 1    108.76 ? 117 ARG A CD  1 -0.22  0.141  -0.062 
ATOM   741   N  NE  . ARG A 1 128 ? -25.001 15.385  -26.087 1    122.76 ? 117 ARG A NE  1 -0.229 0.141  -0.065 
ATOM   742   C  CZ  . ARG A 1 128 ? -26.026 16.231  -26.168 1    129.15 ? 117 ARG A CZ  1 -0.239 0.149  -0.065 
ATOM   743   N  NH1 . ARG A 1 128 ? -26.206 17.203  -25.277 1    126.75 ? 117 ARG A NH1 1 -0.24  0.158  -0.063 
ATOM   744   N  NH2 . ARG A 1 128 ? -26.907 16.094  -27.163 1    139.17 ? 117 ARG A NH2 1 -0.247 0.147  -0.068 
ATOM   745   N  N   . ALA A 1 129 ? -27.004 12.52   -20.773 1    97.04  ? 118 ALA A N   1 -0.247 0.115  -0.052 
ATOM   746   C  CA  . ALA A 1 129 ? -28.41  12.484  -20.393 1    98.94  ? 118 ALA A CA  1 -0.26  0.114  -0.051 
ATOM   747   C  C   . ALA A 1 129 ? -28.757 13.566  -19.38  1    98.13  ? 118 ALA A C   1 -0.264 0.124  -0.048 
ATOM   748   O  O   . ALA A 1 129 ? -29.934 13.918  -19.253 1    98.37  ? 118 ALA A O   1 -0.274 0.128  -0.048 
ATOM   749   C  CB  . ALA A 1 129 ? -28.785 11.124  -19.808 1    101.86 ? 118 ALA A CB  1 -0.264 0.102  -0.049 
ATOM   750   N  N   . VAL A 1 130 ? -27.776 14.098  -18.648 1    95.85  ? 119 VAL A N   1 -0.255 0.129  -0.047 
ATOM   751   C  CA  . VAL A 1 130 ? -28.063 15.146  -17.678 1    99.01  ? 119 VAL A CA  1 -0.257 0.139  -0.044 
ATOM   752   C  C   . VAL A 1 130 ? -27.326 16.447  -17.953 1    96.34  ? 119 VAL A C   1 -0.25  0.151  -0.045 
ATOM   753   O  O   . VAL A 1 130 ? -27.694 17.479  -17.366 1    98.5   ? 119 VAL A O   1 -0.254 0.16   -0.043 
ATOM   754   C  CB  . VAL A 1 130 ? -27.781 14.682  -16.232 1    97.6   ? 119 VAL A CB  1 -0.255 0.135  -0.041 
ATOM   755   C  CG1 . VAL A 1 130 ? -28.308 13.259  -15.993 1    90.51  ? 119 VAL A CG1 1 -0.259 0.122  -0.04  
ATOM   756   C  CG2 . VAL A 1 130 ? -26.304 14.813  -15.916 1    95.6   ? 119 VAL A CG2 1 -0.241 0.136  -0.04  
ATOM   757   N  N   . HIS A 1 131 ? -26.318 16.477  -18.812 1    96.11  ? 120 HIS A N   1 -0.241 0.151  -0.047 
ATOM   758   C  CA  . HIS A 1 131 ? -25.565 17.702  -19.032 1    98.83  ? 120 HIS A CA  1 -0.234 0.162  -0.048 
ATOM   759   C  C   . HIS A 1 131 ? -25.547 18.105  -20.496 1    107.89 ? 120 HIS A C   1 -0.234 0.166  -0.051 
ATOM   760   O  O   . HIS A 1 131 ? -25.253 17.283  -21.371 1    110.23 ? 120 HIS A O   1 -0.231 0.158  -0.053 
ATOM   761   C  CB  . HIS A 1 131 ? -24.163 17.554  -18.487 1    98.09  ? 120 HIS A CB  1 -0.221 0.161  -0.046 
ATOM   762   C  CG  . HIS A 1 131 ? -24.115 17.706  -17.009 1    105.5  ? 120 HIS A CG  1 -0.221 0.162  -0.042 
ATOM   763   N  ND1 . HIS A 1 131 ? -24.488 18.874  -16.378 1    101.52 ? 120 HIS A ND1 1 -0.224 0.173  -0.041 
ATOM   764   C  CD2 . HIS A 1 131 ? -23.799 16.828  -16.03  1    97.71  ? 120 HIS A CD2 1 -0.218 0.154  -0.04  
ATOM   765   C  CE1 . HIS A 1 131 ? -24.375 18.716  -15.072 1    92.98  ? 120 HIS A CE1 1 -0.223 0.172  -0.038 
ATOM   766   N  NE2 . HIS A 1 131 ? -23.971 17.48   -14.835 1    91.9   ? 120 HIS A NE2 1 -0.22  0.16   -0.037 
ATOM   767   N  N   . SER A 1 132 ? -25.856 19.381  -20.747 1    107.97 ? 121 SER A N   1 -0.237 0.178  -0.052 
ATOM   768   C  CA  . SER A 1 132 ? -25.891 19.917  -22.097 1    103.7  ? 121 SER A CA  1 -0.237 0.183  -0.055 
ATOM   769   C  C   . SER A 1 132 ? -24.511 19.837  -22.737 1    108.18 ? 121 SER A C   1 -0.225 0.182  -0.057 
ATOM   770   O  O   . SER A 1 132 ? -23.478 19.983  -22.065 1    101.59 ? 121 SER A O   1 -0.215 0.183  -0.055 
ATOM   771   C  CB  . SER A 1 132 ? -26.398 21.366  -22.075 1    101.69 ? 121 SER A CB  1 -0.242 0.196  -0.055 
ATOM   772   O  OG  . SER A 1 132 ? -25.338 22.316  -22.049 1    98.14  ? 121 SER A OG  1 -0.232 0.205  -0.055 
ATOM   773   N  N   . GLU A 1 133 ? -24.507 19.587  -24.05  1    109.02 ? 122 GLU A N   1 -0.225 0.179  -0.06  
ATOM   774   C  CA  . GLU A 1 133 ? -23.252 19.532  -24.792 1    111.92 ? 122 GLU A CA  1 -0.213 0.179  -0.062 
ATOM   775   C  C   . GLU A 1 133 ? -22.522 20.868  -24.747 1    107.61 ? 122 GLU A C   1 -0.206 0.191  -0.062 
ATOM   776   O  O   . GLU A 1 133 ? -21.287 20.903  -24.73  1    106.38 ? 122 GLU A O   1 -0.195 0.192  -0.062 
ATOM   777   C  CB  . GLU A 1 133 ? -23.507 19.108  -26.242 1    117.23 ? 122 GLU A CB  1 -0.215 0.175  -0.066 
ATOM   778   C  CG  . GLU A 1 133 ? -22.217 18.796  -27.013 1    117.7  ? 122 GLU A CG  1 -0.204 0.172  -0.067 
ATOM   779   C  CD  . GLU A 1 133 ? -22.439 18.378  -28.465 1    128.92 ? 122 GLU A CD  1 -0.206 0.168  -0.071 
ATOM   780   O  OE1 . GLU A 1 133 ? -23.089 17.334  -28.711 1    131.91 ? 122 GLU A OE1 1 -0.212 0.159  -0.072 
ATOM   781   O  OE2 . GLU A 1 133 ? -21.957 19.094  -29.374 1    137.57 ? 122 GLU A OE2 1 -0.201 0.175  -0.073 
ATOM   782   N  N   . ASP A 1 134 ? -23.256 21.977  -24.714 1    104.36 ? 123 ASP A N   1 -0.213 0.201  -0.062 
ATOM   783   C  CA  . ASP A 1 134 ? -22.59  23.267  -24.589 1    109.68 ? 123 ASP A CA  1 -0.207 0.213  -0.061 
ATOM   784   C  C   . ASP A 1 134 ? -21.9   23.415  -23.237 1    111.4  ? 123 ASP A C   1 -0.201 0.215  -0.058 
ATOM   785   O  O   . ASP A 1 134 ? -20.784 23.945  -23.157 1    109.71 ? 123 ASP A O   1 -0.19  0.219  -0.058 
ATOM   786   C  CB  . ASP A 1 134 ? -23.592 24.393  -24.825 1    118.4  ? 123 ASP A CB  1 -0.216 0.224  -0.062 
ATOM   787   C  CG  . ASP A 1 134 ? -23.452 24.995  -26.212 1    126.74 ? 123 ASP A CG  1 -0.215 0.229  -0.065 
ATOM   788   O  OD1 . ASP A 1 134 ? -22.32  25.433  -26.52  1    125.35 ? 123 ASP A OD1 1 -0.205 0.233  -0.066 
ATOM   789   O  OD2 . ASP A 1 134 ? -24.441 24.999  -26.996 1    125.85 ? 123 ASP A OD2 1 -0.224 0.229  -0.067 
ATOM   790   N  N   . TYR A 1 135 ? -22.534 22.952  -22.157 1    107.69 ? 124 TYR A N   1 -0.207 0.21   -0.055 
ATOM   791   C  CA  . TYR A 1 135 ? -21.861 23.04   -20.864 1    112.08 ? 124 TYR A CA  1 -0.2   0.211  -0.052 
ATOM   792   C  C   . TYR A 1 135 ? -20.561 22.24   -20.885 1    110.31 ? 124 TYR A C   1 -0.188 0.204  -0.052 
ATOM   793   O  O   . TYR A 1 135 ? -19.508 22.739  -20.46  1    106.07 ? 124 TYR A O   1 -0.179 0.208  -0.051 
ATOM   794   C  CB  . TYR A 1 135 ? -22.792 22.575  -19.734 1    105.6  ? 124 TYR A CB  1 -0.209 0.207  -0.049 
ATOM   795   C  CG  . TYR A 1 135 ? -22.166 22.618  -18.36  1    107.14 ? 124 TYR A CG  1 -0.203 0.207  -0.046 
ATOM   796   C  CD1 . TYR A 1 135 ? -21.53  23.77   -17.895 1    111.77 ? 124 TYR A CD1 1 -0.197 0.218  -0.045 
ATOM   797   C  CD2 . TYR A 1 135 ? -22.218 21.512  -17.509 1    110.25 ? 124 TYR A CD2 1 -0.204 0.197  -0.044 
ATOM   798   C  CE1 . TYR A 1 135 ? -20.944 23.813  -16.621 1    100.43 ? 124 TYR A CE1 1 -0.192 0.218  -0.041 
ATOM   799   C  CE2 . TYR A 1 135 ? -21.637 21.553  -16.232 1    102.91 ? 124 TYR A CE2 1 -0.198 0.198  -0.041 
ATOM   800   C  CZ  . TYR A 1 135 ? -21.004 22.703  -15.812 1    99.26  ? 124 TYR A CZ  1 -0.192 0.208  -0.039 
ATOM   801   O  OH  . TYR A 1 135 ? -20.441 22.744  -14.567 1    110.89 ? 124 TYR A OH  1 -0.187 0.208  -0.036 
ATOM   802   N  N   . LEU A 1 136 ? -20.602 21.021  -21.433 1    102.34 ? 125 LEU A N   1 -0.189 0.193  -0.054 
ATOM   803   C  CA  . LEU A 1 136 ? -19.409 20.185  -21.407 1    101.69 ? 125 LEU A CA  1 -0.178 0.185  -0.053 
ATOM   804   C  C   . LEU A 1 136 ? -18.307 20.76   -22.277 1    107.74 ? 125 LEU A C   1 -0.168 0.19   -0.056 
ATOM   805   O  O   . LEU A 1 136 ? -17.121 20.548  -21.999 1    106.18 ? 125 LEU A O   1 -0.157 0.188  -0.055 
ATOM   806   C  CB  . LEU A 1 136 ? -19.724 18.782  -21.88  1    104.11 ? 125 LEU A CB  1 -0.181 0.172  -0.055 
ATOM   807   C  CG  . LEU A 1 136 ? -20.277 17.711  -20.957 1    107.06 ? 125 LEU A CG  1 -0.186 0.162  -0.052 
ATOM   808   C  CD1 . LEU A 1 136 ? -21.223 18.262  -19.911 1    108.66 ? 125 LEU A CD1 1 -0.194 0.167  -0.05  
ATOM   809   C  CD2 . LEU A 1 136 ? -20.998 16.76   -21.874 1    106.98 ? 125 LEU A CD2 1 -0.192 0.154  -0.055 
ATOM   810   N  N   . TYR A 1 137 ? -18.678 21.436  -23.363 1    112.49 ? 126 TYR A N   1 -0.171 0.196  -0.058 
ATOM   811   C  CA  . TYR A 1 137 ? -17.682 22.129  -24.165 1    114.76 ? 126 TYR A CA  1 -0.162 0.203  -0.06  
ATOM   812   C  C   . TYR A 1 137 ? -17.053 23.254  -23.363 1    106.64 ? 126 TYR A C   1 -0.156 0.213  -0.058 
ATOM   813   O  O   . TYR A 1 137 ? -15.824 23.356  -23.271 1    102.29 ? 126 TYR A O   1 -0.145 0.214  -0.058 
ATOM   814   C  CB  . TYR A 1 137 ? -18.316 22.678  -25.449 1    113.79 ? 126 TYR A CB  1 -0.168 0.208  -0.064 
ATOM   815   C  CG  . TYR A 1 137 ? -18.271 21.728  -26.614 1    113.61 ? 126 TYR A CG  1 -0.167 0.199  -0.066 
ATOM   816   C  CD1 . TYR A 1 137 ? -17.138 21.602  -27.368 1    112.8  ? 126 TYR A CD1 1 -0.157 0.198  -0.068 
ATOM   817   C  CD2 . TYR A 1 137 ? -19.377 20.97   -26.971 1    119.96 ? 126 TYR A CD2 1 -0.178 0.192  -0.067 
ATOM   818   C  CE1 . TYR A 1 137 ? -17.08  20.741  -28.45  1    121.53 ? 126 TYR A CE1 1 -0.157 0.19   -0.071 
ATOM   819   C  CE2 . TYR A 1 137 ? -19.34  20.098  -28.05  1    119.75 ? 126 TYR A CE2 1 -0.177 0.184  -0.07  
ATOM   820   C  CZ  . TYR A 1 137 ? -18.184 19.988  -28.791 1    123.45 ? 126 TYR A CZ  1 -0.167 0.183  -0.072 
ATOM   821   O  OH  . TYR A 1 137 ? -18.118 19.131  -29.877 1    120.21 ? 126 TYR A OH  1 -0.166 0.175  -0.075 
ATOM   822   N  N   . GLN A 1 138 ? -17.896 24.111  -22.782 1    103.79 ? 127 GLN A N   1 -0.164 0.221  -0.057 
ATOM   823   C  CA  . GLN A 1 138 ? -17.411 25.233  -21.999 1    105.89 ? 127 GLN A CA  1 -0.16  0.231  -0.055 
ATOM   824   C  C   . GLN A 1 138 ? -16.5   24.744  -20.88  1    106.46 ? 127 GLN A C   1 -0.151 0.227  -0.052 
ATOM   825   O  O   . GLN A 1 138 ? -15.53  25.42   -20.514 1    101.59 ? 127 GLN A O   1 -0.142 0.233  -0.051 
ATOM   826   C  CB  . GLN A 1 138 ? -18.627 25.999  -21.475 1    102.53 ? 127 GLN A CB  1 -0.171 0.238  -0.054 
ATOM   827   C  CG  . GLN A 1 138 ? -18.378 27.359  -20.851 1    111.88 ? 127 GLN A CG  1 -0.168 0.251  -0.052 
ATOM   828   C  CD  . GLN A 1 138 ? -19.596 27.832  -20.032 1    130.56 ? 127 GLN A CD  1 -0.18  0.255  -0.05  
ATOM   829   O  OE1 . GLN A 1 138 ? -19.475 28.201  -18.843 1    128.05 ? 127 GLN A OE1 1 -0.178 0.258  -0.047 
ATOM   830   N  NE2 . GLN A 1 138 ? -20.778 27.801  -20.661 1    126.74 ? 127 GLN A NE2 1 -0.19  0.255  -0.052 
ATOM   831   N  N   . LEU A 1 139 ? -16.744 23.526  -20.399 1    104.69 ? 128 LEU A N   1 -0.153 0.216  -0.051 
ATOM   832   C  CA  . LEU A 1 139 ? -16.011 22.975  -19.26  1    108.06 ? 128 LEU A CA  1 -0.147 0.211  -0.048 
ATOM   833   C  C   . LEU A 1 139 ? -14.628 22.463  -19.655 1    105.19 ? 128 LEU A C   1 -0.134 0.206  -0.049 
ATOM   834   O  O   . LEU A 1 139 ? -13.614 22.927  -19.13  1    110.6  ? 128 LEU A O   1 -0.125 0.21   -0.048 
ATOM   835   C  CB  . LEU A 1 139 ? -16.86  21.871  -18.629 1    110.14 ? 128 LEU A CB  1 -0.155 0.2    -0.047 
ATOM   836   C  CG  . LEU A 1 139 ? -16.304 20.887  -17.633 1    100.18 ? 128 LEU A CG  1 -0.149 0.191  -0.044 
ATOM   837   C  CD1 . LEU A 1 139 ? -15.543 21.629  -16.59  1    107.88 ? 128 LEU A CD1 1 -0.142 0.198  -0.041 
ATOM   838   C  CD2 . LEU A 1 139 ? -17.528 20.227  -17.06  1    97.69  ? 128 LEU A CD2 1 -0.161 0.185  -0.043 
ATOM   839   N  N   . ILE A 1 140 ? -14.581 21.471  -20.544 1    107.7  ? 129 ILE A N   1 -0.134 0.197  -0.051 
ATOM   840   C  CA  . ILE A 1 140 ? -13.36  21.075  -21.243 1    107.21 ? 129 ILE A CA  1 -0.122 0.193  -0.053 
ATOM   841   C  C   . ILE A 1 140 ? -12.564 22.32   -21.605 1    107.76 ? 129 ILE A C   1 -0.115 0.205  -0.054 
ATOM   842   O  O   . ILE A 1 140 ? -11.344 22.375  -21.412 1    106.35 ? 129 ILE A O   1 -0.104 0.205  -0.053 
ATOM   843   C  CB  . ILE A 1 140 ? -13.699 20.252  -22.499 1    102.51 ? 129 ILE A CB  1 -0.126 0.186  -0.056 
ATOM   844   C  CG1 . ILE A 1 140 ? -14.211 18.875  -22.081 1    103.38 ? 129 ILE A CG1 1 -0.13  0.173  -0.055 
ATOM   845   C  CG2 . ILE A 1 140 ? -12.492 20.15   -23.442 1    104.66 ? 129 ILE A CG2 1 -0.114 0.185  -0.059 
ATOM   846   C  CD1 . ILE A 1 140 ? -14.797 18.035  -23.191 1    95.15  ? 129 ILE A CD1 1 -0.136 0.165  -0.058 
ATOM   847   N  N   . LYS A 1 141 ? -13.265 23.334  -22.117 1    110.15 ? 130 LYS A N   1 -0.122 0.214  -0.055 
ATOM   848   C  CA  . LYS A 1 141 ? -12.61  24.583  -22.486 1    113.92 ? 130 LYS A CA  1 -0.116 0.225  -0.056 
ATOM   849   C  C   . LYS A 1 141 ? -11.941 25.221  -21.285 1    109.31 ? 130 LYS A C   1 -0.109 0.231  -0.053 
ATOM   850   O  O   . LYS A 1 141 ? -10.808 25.711  -21.38  1    110.86 ? 130 LYS A O   1 -0.099 0.236  -0.053 
ATOM   851   C  CB  . LYS A 1 141 ? -13.627 25.546  -23.108 1    116.9  ? 130 LYS A CB  1 -0.125 0.234  -0.058 
ATOM   852   C  CG  . LYS A 1 141 ? -13.148 26.988  -23.205 1    118.57 ? 130 LYS A CG  1 -0.12  0.247  -0.058 
ATOM   853   C  CD  . LYS A 1 141 ? -14.303 27.925  -23.551 1    118.43 ? 130 LYS A CD  1 -0.131 0.256  -0.059 
ATOM   854   C  CE  . LYS A 1 141 ? -13.83  29.372  -23.588 1    120.46 ? 130 LYS A CE  1 -0.127 0.269  -0.059 
ATOM   855   N  NZ  . LYS A 1 141 ? -14.998 30.287  -23.599 1    117.58 ? 130 LYS A NZ  1 -0.137 0.278  -0.059 
ATOM   856   N  N   . TYR A 1 142 ? -12.628 25.217  -20.142 1    113.58 ? 131 TYR A N   1 -0.116 0.231  -0.05  
ATOM   857   C  CA  . TYR A 1 142 ? -12.088 25.845  -18.942 1    110.09 ? 131 TYR A CA  1 -0.111 0.237  -0.047 
ATOM   858   C  C   . TYR A 1 142 ? -10.911 25.061  -18.38  1    107.72 ? 131 TYR A C   1 -0.1   0.23   -0.046 
ATOM   859   O  O   . TYR A 1 142 ? -9.925  25.658  -17.937 1    110.33 ? 131 TYR A O   1 -0.091 0.235  -0.045 
ATOM   860   C  CB  . TYR A 1 142 ? -13.196 26.008  -17.905 1    101.4  ? 131 TYR A CB  1 -0.121 0.238  -0.045 
ATOM   861   C  CG  . TYR A 1 142 ? -14.082 27.182  -18.218 1    105.55 ? 131 TYR A CG  1 -0.129 0.249  -0.045 
ATOM   862   C  CD1 . TYR A 1 142 ? -13.554 28.312  -18.834 1    112.31 ? 131 TYR A CD1 1 -0.124 0.259  -0.047 
ATOM   863   C  CD2 . TYR A 1 142 ? -15.441 27.163  -17.921 1    106.81 ? 131 TYR A CD2 1 -0.142 0.249  -0.045 
ATOM   864   C  CE1 . TYR A 1 142 ? -14.351 29.403  -19.139 1    118    ? 131 TYR A CE1 1 -0.132 0.269  -0.048 
ATOM   865   C  CE2 . TYR A 1 142 ? -16.252 28.257  -18.217 1    112.23 ? 131 TYR A CE2 1 -0.149 0.259  -0.045 
ATOM   866   C  CZ  . TYR A 1 142 ? -15.699 29.371  -18.83  1    117.59 ? 131 TYR A CZ  1 -0.144 0.269  -0.047 
ATOM   867   O  OH  . TYR A 1 142 ? -16.483 30.464  -19.133 1    126.88 ? 131 TYR A OH  1 -0.151 0.279  -0.048 
ATOM   868   N  N   . CYS A 1 143 ? -10.982 23.726  -18.407 1    106.04 ? 132 CYS A N   1 -0.101 0.217  -0.046 
ATOM   869   C  CA  . CYS A 1 143 ? -9.885  22.917  -17.881 1    107.95 ? 132 CYS A CA  1 -0.091 0.21   -0.045 
ATOM   870   C  C   . CYS A 1 143 ? -8.581  23.244  -18.591 1    112.92 ? 132 CYS A C   1 -0.079 0.213  -0.046 
ATOM   871   O  O   . CYS A 1 143 ? -7.541  23.434  -17.948 1    113.3  ? 132 CYS A O   1 -0.069 0.215  -0.045 
ATOM   872   C  CB  . CYS A 1 143 ? -10.202 21.427  -18.016 1    112.05 ? 132 CYS A CB  1 -0.093 0.196  -0.045 
ATOM   873   S  SG  . CYS A 1 143 ? -11.322 20.73   -16.738 1    106.11 ? 132 CYS A SG  1 -0.104 0.19   -0.042 
ATOM   874   N  N   . ILE A 1 144 ? -8.628  23.317  -19.926 1    116.19 ? 133 ILE A N   1 -0.079 0.214  -0.05  
ATOM   875   C  CA  . ILE A 1 144 ? -7.446  23.647  -20.717 1    112.09 ? 133 ILE A CA  1 -0.068 0.217  -0.052 
ATOM   876   C  C   . ILE A 1 144 ? -7.064  25.105  -20.51  1    108.76 ? 133 ILE A C   1 -0.065 0.23   -0.051 
ATOM   877   O  O   . ILE A 1 144 ? -5.894  25.431  -20.278 1    108.75 ? 133 ILE A O   1 -0.054 0.233  -0.051 
ATOM   878   C  CB  . ILE A 1 144 ? -7.702  23.33   -22.203 1    117.35 ? 133 ILE A CB  1 -0.071 0.214  -0.055 
ATOM   879   C  CG1 . ILE A 1 144 ? -7.887  21.823  -22.404 1    116.59 ? 133 ILE A CG1 1 -0.072 0.2    -0.056 
ATOM   880   C  CG2 . ILE A 1 144 ? -6.577  23.861  -23.085 1    115.66 ? 133 ILE A CG2 1 -0.06  0.219  -0.058 
ATOM   881   C  CD1 . ILE A 1 144 ? -8.087  21.4    -23.857 1    114.54 ? 133 ILE A CD1 1 -0.074 0.196  -0.06  
ATOM   882   N  N   . GLN A 1 145 ? -8.051  26.003  -20.585 1    109.61 ? 134 GLN A N   1 -0.074 0.238  -0.051 
ATOM   883   C  CA  . GLN A 1 145 ? -7.818  27.414  -20.308 1    111.9  ? 134 GLN A CA  1 -0.072 0.251  -0.051 
ATOM   884   C  C   . GLN A 1 145 ? -7.243  27.619  -18.918 1    113.82 ? 134 GLN A C   1 -0.066 0.253  -0.047 
ATOM   885   O  O   . GLN A 1 145 ? -6.633  28.659  -18.652 1    117.8  ? 134 GLN A O   1 -0.061 0.263  -0.047 
ATOM   886   C  CB  . GLN A 1 145 ? -9.128  28.189  -20.475 1    113.68 ? 134 GLN A CB  1 -0.084 0.258  -0.051 
ATOM   887   C  CG  . GLN A 1 145 ? -9.009  29.703  -20.522 1    117.6  ? 134 GLN A CG  1 -0.083 0.272  -0.051 
ATOM   888   C  CD  . GLN A 1 145 ? -10.31  30.35   -20.976 1    123.77 ? 134 GLN A CD  1 -0.094 0.278  -0.052 
ATOM   889   O  OE1 . GLN A 1 145 ? -11.008 29.818  -21.85  1    123.35 ? 134 GLN A OE1 1 -0.101 0.273  -0.055 
ATOM   890   N  NE2 . GLN A 1 145 ? -10.655 31.492  -20.374 1    123.11 ? 134 GLN A NE2 1 -0.098 0.289  -0.051 
ATOM   891   N  N   . ALA A 1 146 ? -7.402  26.632  -18.033 1    116.52 ? 135 ALA A N   1 -0.068 0.244  -0.045 
ATOM   892   C  CA  . ALA A 1 146 ? -6.878  26.717  -16.676 1    114.98 ? 135 ALA A CA  1 -0.063 0.245  -0.042 
ATOM   893   C  C   . ALA A 1 146 ? -5.4    26.359  -16.593 1    116.81 ? 135 ALA A C   1 -0.049 0.242  -0.041 
ATOM   894   O  O   . ALA A 1 146 ? -4.706  26.82   -15.679 1    118.41 ? 135 ALA A O   1 -0.043 0.246  -0.039 
ATOM   895   C  CB  . ALA A 1 146 ? -7.674  25.791  -15.759 1    113.76 ? 135 ALA A CB  1 -0.07  0.236  -0.039 
ATOM   896   N  N   . LYS A 1 147 ? -4.9    25.551  -17.529 1    115.22 ? 136 LYS A N   1 -0.045 0.234  -0.044 
ATOM   897   C  CA  . LYS A 1 147 ? -3.562  24.984  -17.396 1    116.68 ? 136 LYS A CA  1 -0.033 0.229  -0.043 
ATOM   898   C  C   . LYS A 1 147 ? -2.464  26.039  -17.3   1    120.62 ? 136 LYS A C   1 -0.023 0.239  -0.043 
ATOM   899   O  O   . LYS A 1 147 ? -1.328  25.701  -16.948 1    123.03 ? 136 LYS A O   1 -0.012 0.236  -0.042 
ATOM   900   C  CB  . LYS A 1 147 ? -3.289  24.039  -18.563 1    112.89 ? 136 LYS A CB  1 -0.03  0.22   -0.046 
ATOM   901   C  CG  . LYS A 1 147 ? -2.065  23.163  -18.373 1    117.92 ? 136 LYS A CG  1 -0.019 0.212  -0.046 
ATOM   902   C  CD  . LYS A 1 147 ? -1.977  22.113  -19.448 1    119.9  ? 136 LYS A CD  1 -0.018 0.203  -0.049 
ATOM   903   C  CE  . LYS A 1 147 ? -2.216  22.725  -20.808 1    119.88 ? 136 LYS A CE  1 -0.02  0.208  -0.052 
ATOM   904   N  NZ  . LYS A 1 147 ? -2.227  21.676  -21.85  1    120.58 ? 136 LYS A NZ  1 -0.02  0.199  -0.055 
ATOM   905   N  N   . HIS A 1 148 ? -2.762  27.302  -17.575 1    123.95 ? 137 HIS A N   1 -0.025 0.25   -0.044 
ATOM   906   C  CA  . HIS A 1 148 ? -1.729  28.316  -17.439 1    128.98 ? 137 HIS A CA  1 -0.016 0.259  -0.044 
ATOM   907   C  C   . HIS A 1 148 ? -1.387  28.519  -15.97  1    128.52 ? 137 HIS A C   1 -0.013 0.261  -0.04  
ATOM   908   O  O   . HIS A 1 148 ? -0.314  28.116  -15.509 1    126.58 ? 137 HIS A O   1 -0.003 0.258  -0.039 
ATOM   909   C  CB  . HIS A 1 148 ? -2.174  29.634  -18.071 1    134.36 ? 137 HIS A CB  1 -0.02  0.272  -0.045 
ATOM   910   C  CG  . HIS A 1 148 ? -1.036  30.545  -18.419 1    143.85 ? 137 HIS A CG  1 -0.009 0.28   -0.046 
ATOM   911   N  ND1 . HIS A 1 148 ? 0.228   30.392  -17.888 1    143.33 ? 137 HIS A ND1 1 0.002  0.279  -0.045 
ATOM   912   C  CD2 . HIS A 1 148 ? -0.968  31.608  -19.256 1    148.65 ? 137 HIS A CD2 1 -0.009 0.29   -0.048 
ATOM   913   C  CE1 . HIS A 1 148 ? 1.024   31.327  -18.376 1    146.69 ? 137 HIS A CE1 1 0.009  0.287  -0.046 
ATOM   914   N  NE2 . HIS A 1 148 ? 0.323   32.078  -19.208 1    152.27 ? 137 HIS A NE2 1 0.003  0.294  -0.048 
ATOM   915   N  N   . PHE A 1 149 ? -2.299  29.135  -15.231 1    127.52 ? 138 PHE A N   1 -0.021 0.267  -0.038 
ATOM   916   C  CA  . PHE A 1 149 ? -2.095  29.436  -13.822 1    130.47 ? 138 PHE A CA  1 -0.019 0.27   -0.035 
ATOM   917   C  C   . PHE A 1 149 ? -2.317  28.234  -12.906 1    125.53 ? 138 PHE A C   1 -0.021 0.259  -0.032 
ATOM   918   O  O   . PHE A 1 149 ? -2.358  28.418  -11.69  1    126.02 ? 138 PHE A O   1 -0.022 0.26   -0.029 
ATOM   919   C  CB  . PHE A 1 149 ? -3.019  30.583  -13.396 1    131.21 ? 138 PHE A CB  1 -0.028 0.28   -0.033 
ATOM   920   C  CG  . PHE A 1 149 ? -2.475  31.952  -13.713 1    138.37 ? 138 PHE A CG  1 -0.023 0.293  -0.034 
ATOM   921   C  CD1 . PHE A 1 149 ? -1.461  32.115  -14.647 1    129.94 ? 138 PHE A CD1 1 -0.013 0.294  -0.037 
ATOM   922   C  CD2 . PHE A 1 149 ? -2.961  33.076  -13.051 1    141.17 ? 138 PHE A CD2 1 -0.027 0.303  -0.033 
ATOM   923   C  CE1 . PHE A 1 149 ? -0.958  33.369  -14.92  1    132.9  ? 138 PHE A CE1 1 -0.009 0.306  -0.037 
ATOM   924   C  CE2 . PHE A 1 149 ? -2.457  34.337  -13.323 1    137.21 ? 138 PHE A CE2 1 -0.023 0.315  -0.033 
ATOM   925   C  CZ  . PHE A 1 149 ? -1.455  34.482  -14.257 1    135.48 ? 138 PHE A CZ  1 -0.013 0.316  -0.036 
ATOM   926   N  N   . GLY A 1 150 ? -2.458  27.022  -13.442 1    126.58 ? 139 GLY A N   1 -0.023 0.248  -0.034 
ATOM   927   C  CA  . GLY A 1 150 ? -2.806  25.871  -12.632 1    120.39 ? 139 GLY A CA  1 -0.026 0.237  -0.032 
ATOM   928   C  C   . GLY A 1 150 ? -4.231  25.852  -12.117 1    118.85 ? 139 GLY A C   1 -0.039 0.237  -0.03  
ATOM   929   O  O   . GLY A 1 150 ? -4.632  24.859  -11.492 1    111.44 ? 139 GLY A O   1 -0.042 0.228  -0.029 
ATOM   930   N  N   . PHE A 1 151 ? -5.009  26.905  -12.367 1    115.18 ? 140 PHE A N   1 -0.046 0.247  -0.031 
ATOM   931   C  CA  . PHE A 1 151 ? -6.37   27.024  -11.868 1    118.26 ? 140 PHE A CA  1 -0.058 0.248  -0.03  
ATOM   932   C  C   . PHE A 1 151 ? -7.049  28.165  -12.609 1    114.62 ? 140 PHE A C   1 -0.065 0.258  -0.031 
ATOM   933   O  O   . PHE A 1 151 ? -6.422  29.196  -12.867 1    118.49 ? 140 PHE A O   1 -0.059 0.268  -0.032 
ATOM   934   C  CB  . PHE A 1 151 ? -6.397  27.265  -10.339 1    119.22 ? 140 PHE A CB  1 -0.059 0.25   -0.026 
ATOM   935   C  CG  . PHE A 1 151 ? -6.244  28.721  -9.929  1    120.18 ? 140 PHE A CG  1 -0.057 0.263  -0.025 
ATOM   936   C  CD1 . PHE A 1 151 ? -4.993  29.319  -9.868  1    121.38 ? 140 PHE A CD1 1 -0.046 0.269  -0.025 
ATOM   937   C  CD2 . PHE A 1 151 ? -7.357  29.483  -9.596  1    122.45 ? 140 PHE A CD2 1 -0.067 0.27   -0.024 
ATOM   938   C  CE1 . PHE A 1 151 ? -4.857  30.651  -9.497  1    122.85 ? 140 PHE A CE1 1 -0.045 0.281  -0.024 
ATOM   939   C  CE2 . PHE A 1 151 ? -7.226  30.817  -9.217  1    123.71 ? 140 PHE A CE2 1 -0.066 0.282  -0.023 
ATOM   940   C  CZ  . PHE A 1 151 ? -5.974  31.398  -9.169  1    124.37 ? 140 PHE A CZ  1 -0.055 0.288  -0.023 
ATOM   941   N  N   . LYS A 1 152 ? -8.32   27.972  -12.956 1    110.22 ? 141 LYS A N   1 -0.076 0.256  -0.032 
ATOM   942   C  CA  . LYS A 1 152 ? -9.123  28.988  -13.626 1    114.62 ? 141 LYS A CA  1 -0.084 0.266  -0.034 
ATOM   943   C  C   . LYS A 1 152 ? -10.351 29.246  -12.768 1    107.55 ? 141 LYS A C   1 -0.095 0.268  -0.032 
ATOM   944   O  O   . LYS A 1 152 ? -11.185 28.351  -12.581 1    103.5  ? 141 LYS A O   1 -0.103 0.26   -0.031 
ATOM   945   C  CB  . LYS A 1 152 ? -9.512  28.548  -15.052 1    114.96 ? 141 LYS A CB  1 -0.087 0.262  -0.038 
ATOM   946   C  CG  . LYS A 1 152 ? -10.514 29.441  -15.836 1    112.02 ? 141 LYS A CG  1 -0.096 0.27   -0.04  
ATOM   947   C  CD  . LYS A 1 152 ? -9.895  30.733  -16.384 1    115.82 ? 141 LYS A CD  1 -0.091 0.282  -0.041 
ATOM   948   C  CE  . LYS A 1 152 ? -10.949 31.609  -17.062 1    118.09 ? 141 LYS A CE  1 -0.1   0.29   -0.043 
ATOM   949   N  NZ  . LYS A 1 152 ? -10.512 33.042  -17.154 1    127.03 ? 141 LYS A NZ  1 -0.096 0.303  -0.043 
ATOM   950   N  N   . GLN A 1 153 ? -10.449 30.461  -12.241 1    106.58 ? 142 GLN A N   1 -0.096 0.279  -0.031 
ATOM   951   C  CA  . GLN A 1 153 ? -11.57  30.836  -11.387 1    117.15 ? 142 GLN A CA  1 -0.106 0.283  -0.028 
ATOM   952   C  C   . GLN A 1 153 ? -12.738 31.259  -12.274 1    112.59 ? 142 GLN A C   1 -0.117 0.286  -0.031 
ATOM   953   O  O   . GLN A 1 153 ? -12.613 32.219  -13.038 1    115.05 ? 142 GLN A O   1 -0.116 0.295  -0.033 
ATOM   954   C  CB  . GLN A 1 153 ? -11.161 31.965  -10.428 1    122.57 ? 142 GLN A CB  1 -0.102 0.293  -0.026 
ATOM   955   C  CG  . GLN A 1 153 ? -11.716 31.877  -8.979  1    114.16 ? 142 GLN A CG  1 -0.107 0.292  -0.022 
ATOM   956   C  CD  . GLN A 1 153 ? -13.177 32.312  -8.875  1    124.52 ? 142 GLN A CD  1 -0.121 0.296  -0.022 
ATOM   957   O  OE1 . GLN A 1 153 ? -13.913 32.308  -9.866  1    131.65 ? 142 GLN A OE1 1 -0.128 0.296  -0.025 
ATOM   958   N  NE2 . GLN A 1 153 ? -13.599 32.698  -7.678  1    123.55 ? 142 GLN A NE2 1 -0.125 0.3    -0.019 
ATOM   959   N  N   . LEU A 1 154 ? -13.863 30.539  -12.185 1    112.71 ? 143 LEU A N   1 -0.127 0.28   -0.03  
ATOM   960   C  CA  . LEU A 1 154 ? -15.076 30.96   -12.885 1    117.39 ? 143 LEU A CA  1 -0.138 0.284  -0.032 
ATOM   961   C  C   . LEU A 1 154 ? -15.822 32.023  -12.081 1    122.75 ? 143 LEU A C   1 -0.145 0.293  -0.03  
ATOM   962   O  O   . LEU A 1 154 ? -15.812 33.206  -12.438 1    128.13 ? 143 LEU A O   1 -0.145 0.304  -0.031 
ATOM   963   C  CB  . LEU A 1 154 ? -15.987 29.756  -13.181 1    111.42 ? 143 LEU A CB  1 -0.147 0.273  -0.033 
ATOM   964   C  CG  . LEU A 1 154 ? -15.357 28.564  -13.917 1    103.66 ? 143 LEU A CG  1 -0.141 0.262  -0.035 
ATOM   965   C  CD1 . LEU A 1 154 ? -16.382 27.486  -14.318 1    87.1   ? 143 LEU A CD1 1 -0.15  0.252  -0.036 
ATOM   966   C  CD2 . LEU A 1 154 ? -14.563 29.035  -15.113 1    107.39 ? 143 LEU A CD2 1 -0.133 0.266  -0.038 
ATOM   967   N  N   . ASN A 1 155 ? -16.477 31.62   -10.986 1    123.15 ? 144 ASN A N   1 -0.151 0.29   -0.027 
ATOM   968   C  CA  . ASN A 1 155 ? -17.071 32.563  -10.038 1    126.54 ? 144 ASN A CA  1 -0.156 0.298  -0.025 
ATOM   969   C  C   . ASN A 1 155 ? -16.663 32.154  -8.627  1    128.23 ? 144 ASN A C   1 -0.153 0.295  -0.022 
ATOM   970   O  O   . ASN A 1 155 ? -15.945 31.167  -8.426  1    128.4  ? 144 ASN A O   1 -0.146 0.286  -0.021 
ATOM   971   C  CB  . ASN A 1 155 ? -18.606 32.676  -10.204 1    131.34 ? 144 ASN A CB  1 -0.171 0.299  -0.025 
ATOM   972   C  CG  . ASN A 1 155 ? -19.396 31.543  -9.513  1    130.61 ? 144 ASN A CG  1 -0.178 0.289  -0.024 
ATOM   973   O  OD1 . ASN A 1 155 ? -19.151 31.195  -8.366  1    133.86 ? 144 ASN A OD1 1 -0.176 0.286  -0.021 
ATOM   974   N  ND2 . ASN A 1 155 ? -20.378 31.001  -10.22  1    136.47 ? 144 ASN A ND2 1 -0.187 0.284  -0.026 
ATOM   975   N  N   . ALA A 1 156 ? -17.171 32.901  -7.641  1    127.91 ? 145 ALA A N   1 -0.157 0.302  -0.019 
ATOM   976   C  CA  . ALA A 1 156 ? -16.722 32.769  -6.255  1    127.7  ? 145 ALA A CA  1 -0.153 0.3    -0.016 
ATOM   977   C  C   . ALA A 1 156 ? -16.641 31.323  -5.766  1    128.04 ? 145 ALA A C   1 -0.153 0.287  -0.014 
ATOM   978   O  O   . ALA A 1 156 ? -15.839 31.014  -4.877  1    124.5  ? 145 ALA A O   1 -0.145 0.284  -0.012 
ATOM   979   C  CB  . ALA A 1 156 ? -17.659 33.569  -5.345  1    128.7  ? 145 ALA A CB  1 -0.162 0.308  -0.013 
ATOM   980   N  N   . ASP A 1 157 ? -17.459 30.423  -6.323  1    128.99 ? 146 ASP A N   1 -0.16  0.279  -0.016 
ATOM   981   C  CA  . ASP A 1 157 ? -17.585 29.065  -5.801  1    123.49 ? 146 ASP A CA  1 -0.161 0.266  -0.014 
ATOM   982   C  C   . ASP A 1 157 ? -17.12  27.989  -6.768  1    117.77 ? 146 ASP A C   1 -0.157 0.256  -0.017 
ATOM   983   O  O   . ASP A 1 157 ? -17.381 26.806  -6.524  1    114.53 ? 146 ASP A O   1 -0.159 0.246  -0.016 
ATOM   984   C  CB  . ASP A 1 157 ? -19.035 28.754  -5.423  1    123.27 ? 146 ASP A CB  1 -0.174 0.264  -0.014 
ATOM   985   C  CG  . ASP A 1 157 ? -19.636 29.785  -4.501  1    133.33 ? 146 ASP A CG  1 -0.18  0.273  -0.011 
ATOM   986   O  OD1 . ASP A 1 157 ? -20.815 30.152  -4.725  1    140.65 ? 146 ASP A OD1 1 -0.191 0.276  -0.012 
ATOM   987   O  OD2 . ASP A 1 157 ? -18.934 30.227  -3.562  1    134.05 ? 146 ASP A OD2 1 -0.174 0.277  -0.009 
ATOM   988   N  N   . LEU A 1 158 ? -16.473 28.347  -7.866  1    117.19 ? 147 LEU A N   1 -0.151 0.26   -0.02  
ATOM   989   C  CA  . LEU A 1 158 ? -16.186 27.369  -8.91   1    117.66 ? 147 LEU A CA  1 -0.148 0.251  -0.022 
ATOM   990   C  C   . LEU A 1 158 ? -14.768 27.574  -9.408  1    115.94 ? 147 LEU A C   1 -0.135 0.253  -0.023 
ATOM   991   O  O   . LEU A 1 158 ? -14.494 28.556  -10.107 1    114.79 ? 147 LEU A O   1 -0.133 0.262  -0.025 
ATOM   992   C  CB  . LEU A 1 158 ? -17.168 27.492  -10.069 1    114.58 ? 147 LEU A CB  1 -0.157 0.252  -0.025 
ATOM   993   C  CG  . LEU A 1 158 ? -18.485 26.725  -10.027 1    113.43 ? 147 LEU A CG  1 -0.169 0.245  -0.025 
ATOM   994   C  CD1 . LEU A 1 158 ? -19.176 26.863  -11.392 1    106.48 ? 147 LEU A CD1 1 -0.176 0.246  -0.028 
ATOM   995   C  CD2 . LEU A 1 158 ? -18.264 25.26   -9.663  1    102.15 ? 147 LEU A CD2 1 -0.167 0.231  -0.024 
ATOM   996   N  N   . VAL A 1 159 ? -13.884 26.642  -9.085  1    112.78 ? 148 VAL A N   1 -0.127 0.244  -0.023 
ATOM   997   C  CA  . VAL A 1 159 ? -12.546 26.65   -9.655  1    110.08 ? 148 VAL A CA  1 -0.115 0.244  -0.024 
ATOM   998   C  C   . VAL A 1 159 ? -12.288 25.318  -10.35  1    106.3  ? 148 VAL A C   1 -0.113 0.232  -0.026 
ATOM   999   O  O   . VAL A 1 159 ? -12.848 24.278  -9.986  1    103.08 ? 148 VAL A O   1 -0.118 0.222  -0.025 
ATOM   1000  C  CB  . VAL A 1 159 ? -11.488 26.951  -8.576  1    106.03 ? 148 VAL A CB  1 -0.105 0.247  -0.021 
ATOM   1001  C  CG1 . VAL A 1 159 ? -10.115 27.1    -9.205  1    106.66 ? 148 VAL A CG1 1 -0.093 0.248  -0.023 
ATOM   1002  C  CG2 . VAL A 1 159 ? -11.876 28.219  -7.843  1    107.02 ? 148 VAL A CG2 1 -0.109 0.259  -0.02  
ATOM   1003  N  N   . VAL A 1 160 ? -11.46  25.356  -11.385 1    105.21 ? 149 VAL A N   1 -0.105 0.232  -0.028 
ATOM   1004  C  CA  . VAL A 1 160 ? -11.099 24.152  -12.113 1    103.31 ? 149 VAL A CA  1 -0.102 0.221  -0.03  
ATOM   1005  C  C   . VAL A 1 160 ? -9.598  24.137  -12.318 1    103.52 ? 149 VAL A C   1 -0.088 0.221  -0.031 
ATOM   1006  O  O   . VAL A 1 160 ? -8.972  25.181  -12.516 1    106.48 ? 149 VAL A O   1 -0.082 0.231  -0.031 
ATOM   1007  C  CB  . VAL A 1 160 ? -11.829 24.061  -13.466 1    99.07  ? 149 VAL A CB  1 -0.108 0.22   -0.034 
ATOM   1008  C  CG1 . VAL A 1 160 ? -13.232 23.507  -13.275 1    91.7   ? 149 VAL A CG1 1 -0.121 0.215  -0.033 
ATOM   1009  C  CG2 . VAL A 1 160 ? -11.885 25.429  -14.086 1    107.14 ? 149 VAL A CG2 1 -0.109 0.233  -0.035 
ATOM   1010  N  N   . THR A 1 161 ? -9.031  22.954  -12.256 1    102.01 ? 150 THR A N   1 -0.083 0.21   -0.031 
ATOM   1011  C  CA  . THR A 1 161 ? -7.66   22.645  -12.592 1    107.62 ? 150 THR A CA  1 -0.07  0.208  -0.031 
ATOM   1012  C  C   . THR A 1 161 ? -7.621  21.92   -13.943 1    109.51 ? 150 THR A C   1 -0.07  0.201  -0.035 
ATOM   1013  O  O   . THR A 1 161 ? -8.66   21.471  -14.439 1    104.1  ? 150 THR A O   1 -0.079 0.197  -0.036 
ATOM   1014  C  CB  . THR A 1 161 ? -7.062  21.773  -11.478 1    105.83 ? 150 THR A CB  1 -0.065 0.2    -0.029 
ATOM   1015  O  OG1 . THR A 1 161 ? -6.24   20.733  -12.033 1    104.6  ? 150 THR A OG1 1 -0.057 0.19   -0.03  
ATOM   1016  C  CG2 . THR A 1 161 ? -8.19   21.146  -10.649 1    102.66 ? 150 THR A CG2 1 -0.075 0.194  -0.027 
ATOM   1017  N  N   . PRO A 1 162 ? -6.448  21.843  -14.598 1    107.73 ? 151 PRO A N   1 -0.059 0.2    -0.036 
ATOM   1018  C  CA  . PRO A 1 162 ? -6.36   21.07   -15.853 1    108.43 ? 151 PRO A CA  1 -0.058 0.193  -0.04  
ATOM   1019  C  C   . PRO A 1 162 ? -7.024  19.709  -15.788 1    106.96 ? 151 PRO A C   1 -0.064 0.181  -0.039 
ATOM   1020  O  O   . PRO A 1 162 ? -7.657  19.268  -16.756 1    112.81 ? 151 PRO A O   1 -0.07  0.177  -0.042 
ATOM   1021  C  CB  . PRO A 1 162 ? -4.846  20.932  -16.059 1    110.18 ? 151 PRO A CB  1 -0.044 0.192  -0.04  
ATOM   1022  C  CG  . PRO A 1 162 ? -4.272  22.148  -15.456 1    109.91 ? 151 PRO A CG  1 -0.039 0.203  -0.039 
ATOM   1023  C  CD  . PRO A 1 162 ? -5.212  22.613  -14.353 1    109.72 ? 151 PRO A CD  1 -0.048 0.207  -0.036 
ATOM   1024  N  N   . LYS A 1 163 ? -6.889  19.024  -14.664 1    108.47 ? 152 LYS A N   1 -0.063 0.174  -0.037 
ATOM   1025  C  CA  . LYS A 1 163 ? -7.323  17.643  -14.564 1    107.18 ? 152 LYS A CA  1 -0.067 0.162  -0.036 
ATOM   1026  C  C   . LYS A 1 163 ? -8.7    17.497  -13.913 1    99.52  ? 152 LYS A C   1 -0.08  0.16   -0.035 
ATOM   1027  O  O   . LYS A 1 163 ? -9.117  16.365  -13.641 1    93.79  ? 152 LYS A O   1 -0.084 0.15   -0.034 
ATOM   1028  C  CB  . LYS A 1 163 ? -6.265  16.824  -13.815 1    104.23 ? 152 LYS A CB  1 -0.057 0.154  -0.034 
ATOM   1029  C  CG  . LYS A 1 163 ? -4.86   16.863  -14.471 1    101.05 ? 152 LYS A CG  1 -0.045 0.155  -0.036 
ATOM   1030  C  CD  . LYS A 1 163 ? -3.98   18.088  -14.017 1    112.68 ? 152 LYS A CD  1 -0.036 0.166  -0.035 
ATOM   1031  C  CE  . LYS A 1 163 ? -3.994  18.324  -12.465 1    116.4  ? 152 LYS A CE  1 -0.037 0.168  -0.031 
ATOM   1032  N  NZ  . LYS A 1 163 ? -3.436  19.638  -11.921 1    105.73 ? 152 LYS A NZ  1 -0.031 0.18   -0.03  
ATOM   1033  N  N   . THR A 1 164 ? -9.425  18.605  -13.695 1    92.57  ? 153 THR A N   1 -0.086 0.17   -0.034 
ATOM   1034  C  CA  . THR A 1 164 ? -10.778 18.529  -13.145 1    89.86  ? 153 THR A CA  1 -0.099 0.17   -0.033 
ATOM   1035  C  C   . THR A 1 164 ? -11.63  17.555  -13.936 1    95.42  ? 153 THR A C   1 -0.107 0.161  -0.035 
ATOM   1036  O  O   . THR A 1 164 ? -12.302 16.681  -13.367 1    90.61  ? 153 THR A O   1 -0.113 0.153  -0.033 
ATOM   1037  C  CB  . THR A 1 164 ? -11.433 19.909  -13.167 1    92.4   ? 153 THR A CB  1 -0.105 0.182  -0.033 
ATOM   1038  O  OG1 . THR A 1 164 ? -10.565 20.876  -12.567 1    105.01 ? 153 THR A OG1 1 -0.097 0.191  -0.031 
ATOM   1039  C  CG2 . THR A 1 164 ? -12.721 19.889  -12.419 1    83.64  ? 153 THR A CG2 1 -0.117 0.182  -0.031 
ATOM   1040  N  N   . PHE A 1 165 ? -11.595 17.691  -15.265 1    104.92 ? 154 PHE A N   1 -0.106 0.162  -0.038 
ATOM   1041  C  CA  . PHE A 1 165 ? -12.406 16.842  -16.117 1    93.63  ? 154 PHE A CA  1 -0.114 0.154  -0.04  
ATOM   1042  C  C   . PHE A 1 165 ? -12.008 15.379  -15.978 1    96.04  ? 154 PHE A C   1 -0.11  0.141  -0.04  
ATOM   1043  O  O   . PHE A 1 165 ? -12.875 14.511  -15.827 1    94.55  ? 154 PHE A O   1 -0.118 0.133  -0.04  
ATOM   1044  C  CB  . PHE A 1 165 ? -12.317 17.288  -17.574 1    97.11  ? 154 PHE A CB  1 -0.113 0.158  -0.044 
ATOM   1045  C  CG  . PHE A 1 165 ? -13.389 16.676  -18.431 1    97.38  ? 154 PHE A CG  1 -0.123 0.153  -0.046 
ATOM   1046  C  CD1 . PHE A 1 165 ? -14.647 17.253  -18.497 1    96.06  ? 154 PHE A CD1 1 -0.134 0.158  -0.046 
ATOM   1047  C  CD2 . PHE A 1 165 ? -13.166 15.486  -19.106 1    91.5   ? 154 PHE A CD2 1 -0.121 0.142  -0.048 
ATOM   1048  C  CE1 . PHE A 1 165 ? -15.646 16.677  -19.252 1    85.38  ? 154 PHE A CE1 1 -0.143 0.153  -0.048 
ATOM   1049  C  CE2 . PHE A 1 165 ? -14.166 14.902  -19.847 1    90.13  ? 154 PHE A CE2 1 -0.13  0.137  -0.05  
ATOM   1050  C  CZ  . PHE A 1 165 ? -15.404 15.499  -19.918 1    89.51  ? 154 PHE A CZ  1 -0.141 0.142  -0.05  
ATOM   1051  N  N   . GLU A 1 166 ? -10.696 15.08   -16.01  1    96.12  ? 155 GLU A N   1 -0.098 0.138  -0.04  
ATOM   1052  C  CA  . GLU A 1 166 ? -10.281 13.681  -15.887 1    96.53  ? 155 GLU A CA  1 -0.094 0.125  -0.04  
ATOM   1053  C  C   . GLU A 1 166 ? -10.829 13.058  -14.613 1    101.45 ? 155 GLU A C   1 -0.099 0.12   -0.036 
ATOM   1054  O  O   . GLU A 1 166 ? -11.251 11.896  -14.615 1    98.41  ? 155 GLU A O   1 -0.103 0.109  -0.036 
ATOM   1055  C  CB  . GLU A 1 166 ? -8.755  13.519  -15.933 1    96.82  ? 155 GLU A CB  1 -0.08  0.124  -0.04  
ATOM   1056  C  CG  . GLU A 1 166 ? -8.379  12.133  -16.511 1    105.24 ? 155 GLU A CG  1 -0.077 0.111  -0.041 
ATOM   1057  C  CD  . GLU A 1 166 ? -6.911  11.686  -16.362 1    111.11 ? 155 GLU A CD  1 -0.063 0.107  -0.041 
ATOM   1058  O  OE1 . GLU A 1 166 ? -5.985  12.534  -16.439 1    109.32 ? 155 GLU A OE1 1 -0.055 0.115  -0.041 
ATOM   1059  O  OE2 . GLU A 1 166 ? -6.692  10.452  -16.198 1    105.15 ? 155 GLU A OE2 1 -0.061 0.096  -0.04  
ATOM   1060  N  N   . ILE A 1 167 ? -10.861 13.831  -13.518 1    100.33 ? 156 ILE A N   1 -0.1   0.127  -0.034 
ATOM   1061  C  CA  . ILE A 1 167 ? -11.228 13.28   -12.218 1    94.68  ? 156 ILE A CA  1 -0.103 0.122  -0.031 
ATOM   1062  C  C   . ILE A 1 167 ? -12.735 13.15   -12.093 1    97.99  ? 156 ILE A C   1 -0.117 0.121  -0.03  
ATOM   1063  O  O   . ILE A 1 167 ? -13.24  12.122  -11.62  1    97.17  ? 156 ILE A O   1 -0.121 0.111  -0.029 
ATOM   1064  C  CB  . ILE A 1 167 ? -10.672 14.152  -11.091 1    100.44 ? 156 ILE A CB  1 -0.098 0.13   -0.028 
ATOM   1065  C  CG1 . ILE A 1 167 ? -9.177  14.368  -11.246 1    100.45 ? 156 ILE A CG1 1 -0.084 0.132  -0.028 
ATOM   1066  C  CG2 . ILE A 1 167 ? -10.975 13.524  -9.749  1    100.5  ? 156 ILE A CG2 1 -0.101 0.124  -0.024 
ATOM   1067  C  CD1 . ILE A 1 167 ? -8.697  15.453  -10.303 1    101.53 ? 156 ILE A CD1 1 -0.08  0.142  -0.026 
ATOM   1068  N  N   . LEU A 1 168 ? -13.469 14.215  -12.465 1    94.9   ? 157 LEU A N   1 -0.123 0.13   -0.031 
ATOM   1069  C  CA  . LEU A 1 168 ? -14.928 14.154  -12.467 1    90.88  ? 157 LEU A CA  1 -0.137 0.13   -0.031 
ATOM   1070  C  C   . LEU A 1 168 ? -15.402 12.898  -13.175 1    98.53  ? 157 LEU A C   1 -0.141 0.118  -0.033 
ATOM   1071  O  O   . LEU A 1 168 ? -16.35  12.254  -12.724 1    98.14  ? 157 LEU A O   1 -0.15  0.112  -0.032 
ATOM   1072  C  CB  . LEU A 1 168 ? -15.531 15.38   -13.153 1    86.29  ? 157 LEU A CB  1 -0.142 0.141  -0.033 
ATOM   1073  C  CG  . LEU A 1 168 ? -15.911 16.631  -12.384 1    84.52  ? 157 LEU A CG  1 -0.146 0.152  -0.031 
ATOM   1074  C  CD1 . LEU A 1 168 ? -16.764 16.278  -11.215 1    81.91  ? 157 LEU A CD1 1 -0.154 0.149  -0.028 
ATOM   1075  C  CD2 . LEU A 1 168 ? -14.685 17.312  -11.945 1    92.83  ? 157 LEU A CD2 1 -0.135 0.159  -0.03  
ATOM   1076  N  N   . ILE A 1 169 ? -14.731 12.519  -14.266 1    94.71  ? 158 ILE A N   1 -0.135 0.115  -0.036 
ATOM   1077  C  CA  . ILE A 1 169 ? -15.126 11.353  -15.05  1    99.13  ? 158 ILE A CA  1 -0.139 0.104  -0.038 
ATOM   1078  C  C   . ILE A 1 169 ? -14.529 10.071  -14.477 1    96.01  ? 158 ILE A C   1 -0.133 0.092  -0.036 
ATOM   1079  O  O   . ILE A 1 169 ? -15.212 9.043   -14.404 1    96.49  ? 158 ILE A O   1 -0.139 0.083  -0.036 
ATOM   1080  C  CB  . ILE A 1 169 ? -14.737 11.561  -16.541 1    105.61 ? 158 ILE A CB  1 -0.135 0.106  -0.041 
ATOM   1081  C  CG1 . ILE A 1 169 ? -15.598 12.649  -17.189 1    94.7   ? 158 ILE A CG1 1 -0.143 0.116  -0.043 
ATOM   1082  C  CG2 . ILE A 1 169 ? -14.869 10.265  -17.374 1    92.38  ? 158 ILE A CG2 1 -0.136 0.094  -0.043 
ATOM   1083  C  CD1 . ILE A 1 169 ? -16.9   12.123  -17.755 1    93.1   ? 158 ILE A CD1 1 -0.155 0.111  -0.044 
ATOM   1084  N  N   . ARG A 1 170 ? -13.253 10.095  -14.065 1    94.91  ? 159 ARG A N   1 -0.121 0.093  -0.035 
ATOM   1085  C  CA  . ARG A 1 170 ? -12.687 8.9     -13.441 1    101.18 ? 159 ARG A CA  1 -0.116 0.082  -0.034 
ATOM   1086  C  C   . ARG A 1 170 ? -13.439 8.536   -12.165 1    102.34 ? 159 ARG A C   1 -0.123 0.078  -0.03  
ATOM   1087  O  O   . ARG A 1 170 ? -13.629 7.352   -11.875 1    101.29 ? 159 ARG A O   1 -0.125 0.067  -0.03  
ATOM   1088  C  CB  . ARG A 1 170 ? -11.186 9.084   -13.18  1    99.81  ? 159 ARG A CB  1 -0.103 0.083  -0.033 
ATOM   1089  C  CG  . ARG A 1 170 ? -10.365 8.901   -14.459 1    103.68 ? 159 ARG A CG  1 -0.095 0.082  -0.036 
ATOM   1090  C  CD  . ARG A 1 170 ? -8.861  8.892   -14.232 1    106.05 ? 159 ARG A CD  1 -0.081 0.081  -0.036 
ATOM   1091  N  NE  . ARG A 1 170 ? -8.135  8.175   -15.28  1    105.18 ? 159 ARG A NE  1 -0.075 0.075  -0.038 
ATOM   1092  C  CZ  . ARG A 1 170 ? -7.897  6.865   -15.264 1    112.61 ? 159 ARG A CZ  1 -0.072 0.063  -0.038 
ATOM   1093  N  NH1 . ARG A 1 170 ? -8.381  6.082   -14.3   1    108.14 ? 159 ARG A NH1 1 -0.077 0.056  -0.036 
ATOM   1094  N  NH2 . ARG A 1 170 ? -7.163  6.323   -16.244 1    108.41 ? 159 ARG A NH2 1 -0.066 0.058  -0.041 
ATOM   1095  N  N   . ASP A 1 171 ? -13.921 9.532   -11.42  1    102.98 ? 160 ASP A N   1 -0.128 0.087  -0.029 
ATOM   1096  C  CA  . ASP A 1 171 ? -14.881 9.273   -10.347 1    104.66 ? 160 ASP A CA  1 -0.136 0.085  -0.026 
ATOM   1097  C  C   . ASP A 1 171 ? -16.126 8.565   -10.889 1    104.71 ? 160 ASP A C   1 -0.148 0.078  -0.027 
ATOM   1098  O  O   . ASP A 1 171 ? -16.438 7.433   -10.49  1    102.1  ? 160 ASP A O   1 -0.151 0.068  -0.026 
ATOM   1099  C  CB  . ASP A 1 171 ? -15.241 10.606  -9.666  1    106.37 ? 160 ASP A CB  1 -0.14  0.097  -0.024 
ATOM   1100  C  CG  . ASP A 1 171 ? -16.191 10.458  -8.461  1    109.14 ? 160 ASP A CG  1 -0.148 0.096  -0.021 
ATOM   1101  O  OD1 . ASP A 1 171 ? -17.005 9.508   -8.407  1    110.84 ? 160 ASP A OD1 1 -0.156 0.087  -0.021 
ATOM   1102  O  OD2 . ASP A 1 171 ? -16.141 11.34   -7.566  1    105.91 ? 160 ASP A OD2 1 -0.148 0.104  -0.019 
ATOM   1103  N  N   . CYS A 1 172 ? -16.851 9.232   -11.806 1    106.53 ? 161 CYS A N   1 -0.154 0.085  -0.029 
ATOM   1104  C  CA  . CYS A 1 172 ? -18.113 8.702   -12.326 1    104.19 ? 161 CYS A CA  1 -0.166 0.08   -0.031 
ATOM   1105  C  C   . CYS A 1 172 ? -17.933 7.312   -12.92  1    99.96  ? 161 CYS A C   1 -0.164 0.067  -0.032 
ATOM   1106  O  O   . CYS A 1 172 ? -18.82  6.454   -12.801 1    93.83  ? 161 CYS A O   1 -0.172 0.059  -0.032 
ATOM   1107  C  CB  . CYS A 1 172 ? -18.69  9.651   -13.375 1    99.31  ? 161 CYS A CB  1 -0.171 0.088  -0.033 
ATOM   1108  S  SG  . CYS A 1 172 ? -19.082 11.342  -12.755 1    112.52 ? 161 CYS A SG  1 -0.175 0.104  -0.032 
ATOM   1109  N  N   . ALA A 1 173 ? -16.789 7.074   -13.553 1    98.66  ? 162 ALA A N   1 -0.154 0.065  -0.034 
ATOM   1110  C  CA  . ALA A 1 173 ? -16.441 5.74    -14.011 1    102.76 ? 162 ALA A CA  1 -0.151 0.053  -0.035 
ATOM   1111  C  C   . ALA A 1 173 ? -16.661 4.711   -12.905 1    104.28 ? 162 ALA A C   1 -0.153 0.043  -0.032 
ATOM   1112  O  O   . ALA A 1 173 ? -17.624 3.933   -12.965 1    96.51  ? 162 ALA A O   1 -0.162 0.036  -0.032 
ATOM   1113  C  CB  . ALA A 1 173 ? -14.989 5.702   -14.477 1    98.92  ? 162 ALA A CB  1 -0.137 0.052  -0.036 
ATOM   1114  N  N   . THR A 1 174 ? -15.8   4.753   -11.872 1    106.72 ? 163 THR A N   1 -0.145 0.044  -0.03  
ATOM   1115  C  CA  . THR A 1 174 ? -15.696 3.647   -10.925 1    103.02 ? 163 THR A CA  1 -0.144 0.033  -0.027 
ATOM   1116  C  C   . THR A 1 174 ? -17.043 3.31    -10.298 1    100.84 ? 163 THR A C   1 -0.156 0.03   -0.026 
ATOM   1117  O  O   . THR A 1 174 ? -17.4   2.131   -10.179 1    101.37 ? 163 THR A O   1 -0.159 0.02   -0.025 
ATOM   1118  C  CB  . THR A 1 174 ? -14.666 3.969   -9.845  1    107.93 ? 163 THR A CB  1 -0.134 0.036  -0.025 
ATOM   1119  O  OG1 . THR A 1 174 ? -15.316 4.578   -8.722  1    110.47 ? 163 THR A OG1 1 -0.14  0.042  -0.022 
ATOM   1120  C  CG2 . THR A 1 174 ? -13.608 4.899   -10.399 1    101.07 ? 163 THR A CG2 1 -0.125 0.045  -0.026 
ATOM   1121  N  N   . THR A 1 175 ? -17.825 4.324   -9.928  1    93.45  ? 164 THR A N   1 -0.163 0.04   -0.025 
ATOM   1122  C  CA  . THR A 1 175 ? -19.169 4.058   -9.423  1    96.41  ? 164 THR A CA  1 -0.176 0.037  -0.024 
ATOM   1123  C  C   . THR A 1 175 ? -20.018 3.326   -10.454 1    100.98 ? 164 THR A C   1 -0.183 0.03   -0.026 
ATOM   1124  O  O   . THR A 1 175 ? -20.701 2.347   -10.126 1    94.93  ? 164 THR A O   1 -0.19  0.022  -0.025 
ATOM   1125  C  CB  . THR A 1 175 ? -19.851 5.355   -9.013  1    101.04 ? 164 THR A CB  1 -0.182 0.049  -0.023 
ATOM   1126  O  OG1 . THR A 1 175 ? -19.087 5.991   -7.978  1    105.88 ? 164 THR A OG1 1 -0.175 0.055  -0.02  
ATOM   1127  C  CG2 . THR A 1 175 ? -21.247 5.046   -8.496  1    98.31  ? 164 THR A CG2 1 -0.195 0.046  -0.021 
ATOM   1128  N  N   . LEU A 1 176 ? -20.009 3.815   -11.709 1    109.66 ? 165 LEU A N   1 -0.183 0.035  -0.029 
ATOM   1129  C  CA  . LEU A 1 176 ? -20.778 3.193   -12.784 1    95.27  ? 165 LEU A CA  1 -0.19  0.029  -0.032 
ATOM   1130  C  C   . LEU A 1 176 ? -20.282 1.781   -13.079 1    97.27  ? 165 LEU A C   1 -0.186 0.016  -0.033 
ATOM   1131  O  O   . LEU A 1 176 ? -21.087 0.852   -13.211 1    91.24  ? 165 LEU A O   1 -0.193 0.008  -0.033 
ATOM   1132  C  CB  . LEU A 1 176 ? -20.706 4.064   -14.031 1    99.42  ? 165 LEU A CB  1 -0.19  0.037  -0.035 
ATOM   1133  C  CG  . LEU A 1 176 ? -21.616 5.294   -14.094 1    103.54 ? 165 LEU A CG  1 -0.198 0.049  -0.035 
ATOM   1134  C  CD1 . LEU A 1 176 ? -21.271 6.156   -15.307 1    100.71 ? 165 LEU A CD1 1 -0.195 0.056  -0.038 
ATOM   1135  C  CD2 . LEU A 1 176 ? -23.067 4.87    -14.164 1    101.92 ? 165 LEU A CD2 1 -0.211 0.045  -0.035 
ATOM   1136  N  N   . PHE A 1 177 ? -18.961 1.591   -13.151 1    100.68 ? 166 PHE A N   1 -0.174 0.015  -0.033 
ATOM   1137  C  CA  . PHE A 1 177 ? -18.357 0.308   -13.504 1    107.09 ? 166 PHE A CA  1 -0.168 0.003  -0.034 
ATOM   1138  C  C   . PHE A 1 177 ? -18.231 -0.673  -12.311 1    115.94 ? 166 PHE A C   1 -0.167 -0.006 -0.031 
ATOM   1139  O  O   . PHE A 1 177 ? -17.436 -1.62   -12.407 1    119.9  ? 166 PHE A O   1 -0.16  -0.015 -0.031 
ATOM   1140  C  CB  . PHE A 1 177 ? -16.964 0.521   -14.117 1    105.81 ? 166 PHE A CB  1 -0.155 0.005  -0.035 
ATOM   1141  C  CG  . PHE A 1 177 ? -16.95  1.331   -15.386 1    105.78 ? 166 PHE A CG  1 -0.155 0.012  -0.038 
ATOM   1142  C  CD1 . PHE A 1 177 ? -18.097 1.496   -16.156 1    108.26 ? 166 PHE A CD1 1 -0.166 0.014  -0.04  
ATOM   1143  C  CD2 . PHE A 1 177 ? -15.769 1.919   -15.817 1    112.6  ? 166 PHE A CD2 1 -0.145 0.018  -0.039 
ATOM   1144  C  CE1 . PHE A 1 177 ? -18.069 2.244   -17.337 1    108.86 ? 166 PHE A CE1 1 -0.166 0.021  -0.043 
ATOM   1145  C  CE2 . PHE A 1 177 ? -15.724 2.665   -17.007 1    116.87 ? 166 PHE A CE2 1 -0.144 0.024  -0.042 
ATOM   1146  C  CZ  . PHE A 1 177 ? -16.876 2.829   -17.764 1    111.52 ? 166 PHE A CZ  1 -0.155 0.026  -0.044 
ATOM   1147  N  N   . ASN A 1 178 ? -18.956 -0.501  -11.202 1    118.11 ? 167 ASN A N   1 -0.174 -0.005 -0.028 
ATOM   1148  C  CA  . ASN A 1 178 ? -18.805 -1.427  -10.081 1    122.4  ? 167 ASN A CA  1 -0.172 -0.013 -0.025 
ATOM   1149  C  C   . ASN A 1 178 ? -20.159 -1.878  -9.545  1    126.99 ? 167 ASN A C   1 -0.185 -0.017 -0.024 
ATOM   1150  O  O   . ASN A 1 178 ? -21.056 -1.041  -9.325  1    121.21 ? 167 ASN A O   1 -0.193 -0.01  -0.023 
ATOM   1151  C  CB  . ASN A 1 178 ? -17.963 -0.812  -8.963  1    117.25 ? 167 ASN A CB  1 -0.165 -0.007 -0.022 
ATOM   1152  C  CG  . ASN A 1 178 ? -16.462 -1.023  -9.186  1    125.98 ? 167 ASN A CG  1 -0.151 -0.009 -0.023 
ATOM   1153  O  OD1 . ASN A 1 178 ? -15.928 -0.763  -10.284 1    113.91 ? 167 ASN A OD1 1 -0.146 -0.007 -0.026 
ATOM   1154  N  ND2 . ASN A 1 178 ? -15.775 -1.513  -8.143  1    130.09 ? 167 ASN A ND2 1 -0.145 -0.014 -0.02  
ATOM   1155  N  N   . PRO A 1 179 ? -20.352 -3.205  -9.332  1    135.1  ? 168 PRO A N   1 -0.187 -0.029 -0.023 
ATOM   1156  C  CA  . PRO A 1 179 ? -21.659 -3.771  -8.918  1    134.11 ? 168 PRO A CA  1 -0.198 -0.035 -0.022 
ATOM   1157  C  C   . PRO A 1 179 ? -21.808 -3.883  -7.404  1    135.32 ? 168 PRO A C   1 -0.2   -0.036 -0.018 
ATOM   1158  O  O   . PRO A 1 179 ? -21.906 -4.985  -6.834  1    137.1  ? 168 PRO A O   1 -0.201 -0.046 -0.017 
ATOM   1159  C  CB  . PRO A 1 179 ? -21.643 -5.147  -9.593  1    134.8  ? 168 PRO A CB  1 -0.198 -0.047 -0.024 
ATOM   1160  C  CG  . PRO A 1 179 ? -20.178 -5.555  -9.546  1    133.71 ? 168 PRO A CG  1 -0.185 -0.051 -0.024 
ATOM   1161  C  CD  . PRO A 1 179 ? -19.367 -4.266  -9.641  1    131.31 ? 168 PRO A CD  1 -0.177 -0.039 -0.024 
ATOM   1162  N  N   . ALA A 1 180 ? -21.818 -2.737  -6.723  1    130.07 ? 169 ALA A N   1 -0.2   -0.025 -0.017 
ATOM   1163  C  CA  . ALA A 1 180 ? -22.016 -2.692  -5.279  1    121.49 ? 169 ALA A CA  1 -0.202 -0.025 -0.013 
ATOM   1164  C  C   . ALA A 1 180 ? -23.455 -2.287  -4.992  1    117.27 ? 169 ALA A C   1 -0.215 -0.021 -0.012 
ATOM   1165  O  O   . ALA A 1 180 ? -23.896 -1.214  -5.423  1    119.81 ? 169 ALA A O   1 -0.219 -0.011 -0.014 
ATOM   1166  C  CB  . ALA A 1 180 ? -21.045 -1.716  -4.621  1    121.92 ? 169 ALA A CB  1 -0.193 -0.016 -0.012 
ATOM   1167  N  N   . LYS A 1 181 ? -24.19  -3.145  -4.281  1    109.89 ? 170 LYS A N   1 -0.222 -0.029 -0.011 
ATOM   1168  C  CA  . LYS A 1 181 ? -25.586 -2.828  -4.003  1    113.93 ? 170 LYS A CA  1 -0.234 -0.026 -0.01  
ATOM   1169  C  C   . LYS A 1 181 ? -25.727 -1.644  -3.049  1    114.06 ? 170 LYS A C   1 -0.236 -0.015 -0.008 
ATOM   1170  O  O   . LYS A 1 181 ? -26.764 -0.974  -3.063  1    110.97 ? 170 LYS A O   1 -0.245 -0.009 -0.008 
ATOM   1171  C  CB  . LYS A 1 181 ? -26.315 -4.065  -3.452  1    115.65 ? 170 LYS A CB  1 -0.241 -0.037 -0.009 
ATOM   1172  C  CG  . LYS A 1 181 ? -26.952 -4.972  -4.52   1    117.12 ? 170 LYS A CG  1 -0.247 -0.046 -0.011 
ATOM   1173  C  CD  . LYS A 1 181 ? -28.492 -4.943  -4.475  1    123.46 ? 170 LYS A CD  1 -0.261 -0.045 -0.011 
ATOM   1174  C  CE  . LYS A 1 181 ? -29.028 -5.561  -3.155  1    133.59 ? 170 LYS A CE  1 -0.266 -0.051 -0.008 
ATOM   1175  N  NZ  . LYS A 1 181 ? -30.52  -5.462  -2.914  1    127.43 ? 170 LYS A NZ  1 -0.28  -0.05  -0.007 
ATOM   1176  N  N   . ALA A 1 182 ? -24.704 -1.362  -2.241  1    119.47 ? 171 ALA A N   1 -0.226 -0.012 -0.006 
ATOM   1177  C  CA  . ALA A 1 182 ? -24.702 -0.251  -1.287  1    110.66 ? 171 ALA A CA  1 -0.226 -0.002 -0.003 
ATOM   1178  C  C   . ALA A 1 182 ? -23.39  0.51    -1.474  1    109.34 ? 171 ALA A C   1 -0.214 0.005  -0.004 
ATOM   1179  O  O   . ALA A 1 182 ? -22.342 0.072   -0.984  1    106.96 ? 171 ALA A O   1 -0.205 0.001  -0.002 
ATOM   1180  C  CB  . ALA A 1 182 ? -24.856 -0.756  0.139   1    106.6  ? 171 ALA A CB  1 -0.228 -0.007 0.0    
ATOM   1181  N  N   . HIS A 1 183 ? -23.453 1.636   -2.193  1    106.64 ? 172 HIS A N   1 -0.215 0.015  -0.005 
ATOM   1182  C  CA  . HIS A 1 183 ? -22.275 2.403   -2.584  1    103.96 ? 172 HIS A CA  1 -0.204 0.022  -0.006 
ATOM   1183  C  C   . HIS A 1 183 ? -22.172 3.664   -1.729  1    102.96 ? 172 HIS A C   1 -0.203 0.034  -0.004 
ATOM   1184  O  O   . HIS A 1 183 ? -23.096 4.485   -1.704  1    102.58 ? 172 HIS A O   1 -0.212 0.041  -0.004 
ATOM   1185  C  CB  . HIS A 1 183 ? -22.356 2.779   -4.06   1    103.09 ? 172 HIS A CB  1 -0.205 0.025  -0.01  
ATOM   1186  C  CG  . HIS A 1 183 ? -21.056 2.688   -4.801  1    111.81 ? 172 HIS A CG  1 -0.193 0.025  -0.012 
ATOM   1187  N  ND1 . HIS A 1 183 ? -20.685 1.565   -5.514  1    115.97 ? 172 HIS A ND1 1 -0.19  0.014  -0.014 
ATOM   1188  C  CD2 . HIS A 1 183 ? -20.069 3.599   -4.998  1    110.84 ? 172 HIS A CD2 1 -0.184 0.033  -0.012 
ATOM   1189  C  CE1 . HIS A 1 183 ? -19.516 1.778   -6.095  1    111.97 ? 172 HIS A CE1 1 -0.179 0.016  -0.015 
ATOM   1190  N  NE2 . HIS A 1 183 ? -19.122 3.005   -5.801  1    112.2  ? 172 HIS A NE2 1 -0.175 0.028  -0.014 
ATOM   1191  N  N   . PHE A 1 184 ? -21.058 3.817   -1.027  1    98.09  ? 173 PHE A N   1 -0.193 0.035  -0.003 
ATOM   1192  C  CA  . PHE A 1 184 ? -20.729 5.056   -0.345  1    96.48  ? 173 PHE A CA  1 -0.19  0.046  -0.001 
ATOM   1193  C  C   . PHE A 1 184 ? -19.501 5.618   -1.04   1    95     ? 173 PHE A C   1 -0.179 0.051  -0.003 
ATOM   1194  O  O   . PHE A 1 184 ? -18.448 4.973   -1.063  1    93.37  ? 173 PHE A O   1 -0.169 0.046  -0.003 
ATOM   1195  C  CB  . PHE A 1 184 ? -20.468 4.819   1.141   1    95.35  ? 173 PHE A CB  1 -0.188 0.044  0.003  
ATOM   1196  C  CG  . PHE A 1 184 ? -21.58  4.09    1.841   1    98.87  ? 173 PHE A CG  1 -0.198 0.037  0.005  
ATOM   1197  C  CD1 . PHE A 1 184 ? -21.648 2.702   1.814   1    99.5   ? 173 PHE A CD1 1 -0.198 0.025  0.005  
ATOM   1198  C  CD2 . PHE A 1 184 ? -22.554 4.789   2.538   1    98.63  ? 173 PHE A CD2 1 -0.207 0.044  0.006  
ATOM   1199  C  CE1 . PHE A 1 184 ? -22.673 2.027   2.454   1    99.28  ? 173 PHE A CE1 1 -0.208 0.019  0.006  
ATOM   1200  C  CE2 . PHE A 1 184 ? -23.577 4.123   3.181   1    100.12 ? 173 PHE A CE2 1 -0.216 0.038  0.008  
ATOM   1201  C  CZ  . PHE A 1 184 ? -23.639 2.739   3.14    1    100.97 ? 173 PHE A CZ  1 -0.217 0.025  0.008  
ATOM   1202  N  N   . SER A 1 185 ? -19.635 6.788   -1.643  1    90.35  ? 174 SER A N   1 -0.18  0.062  -0.004 
ATOM   1203  C  CA  . SER A 1 185 ? -18.534 7.335   -2.412  1    99.36  ? 174 SER A CA  1 -0.17  0.067  -0.006 
ATOM   1204  C  C   . SER A 1 185 ? -18.198 8.726   -1.905  1    95.52  ? 174 SER A C   1 -0.167 0.08   -0.005 
ATOM   1205  O  O   . SER A 1 185 ? -19.093 9.542   -1.649  1    91.83  ? 174 SER A O   1 -0.175 0.087  -0.004 
ATOM   1206  C  CB  . SER A 1 185 ? -18.855 7.364   -3.928  1    98.14  ? 174 SER A CB  1 -0.173 0.067  -0.01  
ATOM   1207  O  OG  . SER A 1 185 ? -19.482 8.576   -4.298  1    103.45 ? 174 SER A OG  1 -0.179 0.079  -0.011 
ATOM   1208  N  N   . PHE A 1 186 ? -16.898 8.984   -1.769  1    90.94  ? 175 PHE A N   1 -0.155 0.082  -0.004 
ATOM   1209  C  CA  . PHE A 1 186 ? -16.386 10.245  -1.241  1    96.46  ? 175 PHE A CA  1 -0.15  0.094  -0.003 
ATOM   1210  C  C   . PHE A 1 186 ? -15.611 10.952  -2.338  1    95.27  ? 175 PHE A C   1 -0.143 0.1    -0.006 
ATOM   1211  O  O   . PHE A 1 186 ? -14.484 10.568  -2.664  1    99.13  ? 175 PHE A O   1 -0.133 0.097  -0.007 
ATOM   1212  C  CB  . PHE A 1 186 ? -15.524 10.002  -0.003  1    97.59  ? 175 PHE A CB  1 -0.142 0.092  -0.0   
ATOM   1213  C  CG  . PHE A 1 186 ? -16.298 9.467   1.139   1    88.75  ? 175 PHE A CG  1 -0.149 0.087  0.003  
ATOM   1214  C  CD1 . PHE A 1 186 ? -16.523 8.108   1.253   1    91.89  ? 175 PHE A CD1 1 -0.151 0.074  0.003  
ATOM   1215  C  CD2 . PHE A 1 186 ? -16.861 10.325  2.061   1    93.05  ? 175 PHE A CD2 1 -0.155 0.095  0.005  
ATOM   1216  C  CE1 . PHE A 1 186 ? -17.27  7.605   2.289   1    94.24  ? 175 PHE A CE1 1 -0.158 0.07   0.006  
ATOM   1217  C  CE2 . PHE A 1 186 ? -17.607 9.839   3.114   1    92.88  ? 175 PHE A CE2 1 -0.161 0.09   0.008  
ATOM   1218  C  CZ  . PHE A 1 186 ? -17.813 8.476   3.229   1    95.41  ? 175 PHE A CZ  1 -0.163 0.078  0.008  
ATOM   1219  N  N   . GLY A 1 187 ? -16.217 11.991  -2.907  1    96.78  ? 176 GLY A N   1 -0.149 0.11   -0.007 
ATOM   1220  C  CA  . GLY A 1 187 ? -15.596 12.737  -3.98   1    95.56  ? 176 GLY A CA  1 -0.143 0.117  -0.01  
ATOM   1221  C  C   . GLY A 1 187 ? -15.962 14.205  -3.9    1    97.61  ? 176 GLY A C   1 -0.146 0.13   -0.01  
ATOM   1222  O  O   . GLY A 1 187 ? -16.2   14.714  -2.8    1    103.59 ? 176 GLY A O   1 -0.148 0.135  -0.007 
ATOM   1223  N  N   . LEU A 1 188 ? -15.991 14.888  -5.06   1    87.23  ? 177 LEU A N   1 -0.147 0.136  -0.013 
ATOM   1224  C  CA  . LEU A 1 188 ? -16.423 16.276  -5.173  1    80.5   ? 177 LEU A CA  1 -0.151 0.149  -0.013 
ATOM   1225  C  C   . LEU A 1 188 ? -17.946 16.326  -5.273  1    84.31  ? 177 LEU A C   1 -0.164 0.15   -0.013 
ATOM   1226  O  O   . LEU A 1 188 ? -18.58  15.327  -5.6    1    88.24  ? 177 LEU A O   1 -0.17  0.14   -0.014 
ATOM   1227  C  CB  . LEU A 1 188 ? -15.764 16.911  -6.374  1    86.33  ? 177 LEU A CB  1 -0.144 0.155  -0.016 
ATOM   1228  C  CG  . LEU A 1 188 ? -14.372 17.456  -6.112  1    88.7   ? 177 LEU A CG  1 -0.132 0.16   -0.015 
ATOM   1229  C  CD1 . LEU A 1 188 ? -13.631 17.656  -7.439  1    96.51  ? 177 LEU A CD1 1 -0.125 0.162  -0.019 
ATOM   1230  C  CD2 . LEU A 1 188 ? -14.532 18.776  -5.369  1    90.17  ? 177 LEU A CD2 1 -0.133 0.172  -0.013 
ATOM   1231  N  N   . PRO A 1 189 ? -18.566 17.452  -4.936  1    88.56  ? 178 PRO A N   1 -0.17  0.16   -0.012 
ATOM   1232  C  CA  . PRO A 1 189 ? -20.015 17.442  -4.714  1    94.43  ? 178 PRO A CA  1 -0.183 0.16   -0.012 
ATOM   1233  C  C   . PRO A 1 189 ? -20.789 17.674  -6.012  1    94.93  ? 178 PRO A C   1 -0.191 0.162  -0.015 
ATOM   1234  O  O   . PRO A 1 189 ? -20.223 18.022  -7.049  1    90.64  ? 178 PRO A O   1 -0.185 0.165  -0.018 
ATOM   1235  C  CB  . PRO A 1 189 ? -20.22  18.599  -3.718  1    78.86  ? 178 PRO A CB  1 -0.185 0.17   -0.009 
ATOM   1236  C  CG  . PRO A 1 189 ? -19.164 19.585  -4.108  1    87.88  ? 178 PRO A CG  1 -0.176 0.179  -0.01  
ATOM   1237  C  CD  . PRO A 1 189 ? -17.999 18.799  -4.715  1    86.12  ? 178 PRO A CD  1 -0.165 0.172  -0.012 
ATOM   1238  N  N   . SER A 1 190 ? -22.12  17.513  -5.918  1    94.69  ? 179 SER A N   1 -0.203 0.16   -0.015 
ATOM   1239  C  CA  . SER A 1 190 ? -22.933 17.409  -7.121  1    90.53  ? 179 SER A CA  1 -0.21  0.16   -0.018 
ATOM   1240  C  C   . SER A 1 190 ? -24.317 18.052  -7.053  1    95.4   ? 179 SER A C   1 -0.223 0.165  -0.018 
ATOM   1241  O  O   . SER A 1 190 ? -24.825 18.46   -8.103  1    102.48 ? 179 SER A O   1 -0.227 0.169  -0.02  
ATOM   1242  C  CB  . SER A 1 190 ? -23.098 15.931  -7.5    1    96.49  ? 179 SER A CB  1 -0.212 0.146  -0.019 
ATOM   1243  O  OG  . SER A 1 190 ? -24.215 15.36   -6.832  1    105.16 ? 179 SER A OG  1 -0.222 0.141  -0.017 
ATOM   1244  N  N   . HIS A 1 191 ? -24.977 18.137  -5.901  1    92.83  ? 180 HIS A N   1 -0.229 0.166  -0.015 
ATOM   1245  C  CA  . HIS A 1 191 ? -26.395 18.489  -5.932  1    91.59  ? 180 HIS A CA  1 -0.242 0.169  -0.015 
ATOM   1246  C  C   . HIS A 1 191 ? -26.665 19.945  -6.323  1    92.52  ? 180 HIS A C   1 -0.244 0.183  -0.016 
ATOM   1247  O  O   . HIS A 1 191 ? -27.835 20.321  -6.44   1    92.78  ? 180 HIS A O   1 -0.255 0.186  -0.016 
ATOM   1248  C  CB  . HIS A 1 191 ? -27.042 18.197  -4.575  1    95.9   ? 180 HIS A CB  1 -0.248 0.167  -0.011 
ATOM   1249  C  CG  . HIS A 1 191 ? -26.654 19.165  -3.506  1    100.27 ? 180 HIS A CG  1 -0.244 0.176  -0.009 
ATOM   1250  N  ND1 . HIS A 1 191 ? -27.52  19.557  -2.508  1    95.87  ? 180 HIS A ND1 1 -0.252 0.179  -0.006 
ATOM   1251  C  CD2 . HIS A 1 191 ? -25.499 19.837  -3.288  1    96.21  ? 180 HIS A CD2 1 -0.234 0.182  -0.008 
ATOM   1252  C  CE1 . HIS A 1 191 ? -26.913 20.423  -1.717  1    96.11  ? 180 HIS A CE1 1 -0.247 0.187  -0.004 
ATOM   1253  N  NE2 . HIS A 1 191 ? -25.685 20.612  -2.168  1    96.19  ? 180 HIS A NE2 1 -0.235 0.189  -0.005 
ATOM   1254  N  N   . HIS A 1 192 ? -25.636 20.779  -6.523  1    93.53  ? 181 HIS A N   1 -0.235 0.19   -0.016 
ATOM   1255  C  CA  . HIS A 1 192 ? -25.838 22.124  -7.056  1    90.79  ? 181 HIS A CA  1 -0.237 0.203  -0.018 
ATOM   1256  C  C   . HIS A 1 192 ? -25.588 22.201  -8.552  1    107.04 ? 181 HIS A C   1 -0.234 0.203  -0.021 
ATOM   1257  O  O   . HIS A 1 192 ? -26.085 23.132  -9.205  1    107.18 ? 181 HIS A O   1 -0.239 0.212  -0.023 
ATOM   1258  C  CB  . HIS A 1 192 ? -24.922 23.137  -6.366  1    102.89 ? 181 HIS A CB  1 -0.228 0.212  -0.016 
ATOM   1259  C  CG  . HIS A 1 192 ? -25.222 23.356  -4.908  1    107.43 ? 181 HIS A CG  1 -0.231 0.214  -0.012 
ATOM   1260  N  ND1 . HIS A 1 192 ? -26.504 23.342  -4.392  1    102.9  ? 181 HIS A ND1 1 -0.243 0.214  -0.011 
ATOM   1261  C  CD2 . HIS A 1 192 ? -24.4   23.606  -3.861  1    93.51  ? 181 HIS A CD2 1 -0.224 0.216  -0.01  
ATOM   1262  C  CE1 . HIS A 1 192 ? -26.46  23.578  -3.096  1    93.42  ? 181 HIS A CE1 1 -0.242 0.216  -0.008 
ATOM   1263  N  NE2 . HIS A 1 192 ? -25.196 23.744  -2.749  1    100.65 ? 181 HIS A NE2 1 -0.231 0.218  -0.007 
ATOM   1264  N  N   . ALA A 1 193 ? -24.826 21.256  -9.104  1    107.41 ? 182 ALA A N   1 -0.228 0.195  -0.023 
ATOM   1265  C  CA  . ALA A 1 193 ? -24.622 21.202  -10.543 1    98.63  ? 182 ALA A CA  1 -0.226 0.194  -0.026 
ATOM   1266  C  C   . ALA A 1 193 ? -25.961 21.222  -11.262 1    99.4   ? 182 ALA A C   1 -0.238 0.194  -0.028 
ATOM   1267  O  O   . ALA A 1 193 ? -26.894 20.494  -10.899 1    94.88  ? 182 ALA A O   1 -0.246 0.188  -0.027 
ATOM   1268  C  CB  . ALA A 1 193 ? -23.832 19.95   -10.923 1    95.96  ? 182 ALA A CB  1 -0.218 0.183  -0.027 
ATOM   1269  N  N   . TYR A 1 194 ? -26.055 22.096  -12.257 1    105.87 ? 183 TYR A N   1 -0.239 0.202  -0.031 
ATOM   1270  C  CA  . TYR A 1 194 ? -27.199 22.218  -13.144 1    98.19  ? 183 TYR A CA  1 -0.249 0.204  -0.033 
ATOM   1271  C  C   . TYR A 1 194 ? -26.922 21.485  -14.45  1    105.55 ? 183 TYR A C   1 -0.247 0.197  -0.036 
ATOM   1272  O  O   . TYR A 1 194 ? -25.768 21.264  -14.835 1    104.25 ? 183 TYR A O   1 -0.236 0.195  -0.037 
ATOM   1273  C  CB  . TYR A 1 194 ? -27.503 23.69   -13.433 1    95.86  ? 183 TYR A CB  1 -0.252 0.217  -0.034 
ATOM   1274  C  CG  . TYR A 1 194 ? -28.284 24.391  -12.364 1    96.5   ? 183 TYR A CG  1 -0.259 0.224  -0.031 
ATOM   1275  C  CD1 . TYR A 1 194 ? -29.66  24.222  -12.26  1    99.98  ? 183 TYR A CD1 1 -0.272 0.222  -0.031 
ATOM   1276  C  CD2 . TYR A 1 194 ? -27.65  25.226  -11.445 1    106.97 ? 183 TYR A CD2 1 -0.253 0.231  -0.029 
ATOM   1277  C  CE1 . TYR A 1 194 ? -30.387 24.86   -11.267 1    97.72  ? 183 TYR A CE1 1 -0.278 0.228  -0.028 
ATOM   1278  C  CE2 . TYR A 1 194 ? -28.371 25.87   -10.44  1    96.58  ? 183 TYR A CE2 1 -0.26  0.237  -0.026 
ATOM   1279  C  CZ  . TYR A 1 194 ? -29.735 25.682  -10.37  1    96.55  ? 183 TYR A CZ  1 -0.272 0.235  -0.026 
ATOM   1280  O  OH  . TYR A 1 194 ? -30.462 26.318  -9.404  1    103.19 ? 183 TYR A OH  1 -0.279 0.241  -0.023 
ATOM   1281  N  N   . THR A 1 195 ? -28.005 21.132  -15.151 1    108.62 ? 184 THR A N   1 -0.257 0.194  -0.038 
ATOM   1282  C  CA  . THR A 1 195 ? -27.881 20.479  -16.453 1    106.51 ? 184 THR A CA  1 -0.256 0.188  -0.041 
ATOM   1283  C  C   . THR A 1 195 ? -27.062 21.296  -17.449 1    104.71 ? 184 THR A C   1 -0.248 0.195  -0.044 
ATOM   1284  O  O   . THR A 1 195 ? -26.662 20.758  -18.486 1    102.93 ? 184 THR A O   1 -0.244 0.19   -0.046 
ATOM   1285  C  CB  . THR A 1 195 ? -29.271 20.2    -17.046 1    104.24 ? 184 THR A CB  1 -0.268 0.185  -0.043 
ATOM   1286  O  OG1 . THR A 1 195 ? -29.168 20.173  -18.475 1    109.1  ? 184 THR A OG1 1 -0.267 0.185  -0.046 
ATOM   1287  C  CG2 . THR A 1 195 ? -30.276 21.279  -16.626 1    102.46 ? 184 THR A CG2 1 -0.277 0.195  -0.042 
ATOM   1288  N  N   . GLN A 1 196 ? -26.762 22.556  -17.129 1    106.28 ? 185 GLN A N   1 -0.245 0.207  -0.043 
ATOM   1289  C  CA  . GLN A 1 196 ? -26.284 23.538  -18.096 1    102.54 ? 185 GLN A CA  1 -0.241 0.216  -0.045 
ATOM   1290  C  C   . GLN A 1 196 ? -25.191 24.451  -17.571 1    107.44 ? 185 GLN A C   1 -0.231 0.224  -0.044 
ATOM   1291  O  O   . GLN A 1 196 ? -24.509 25.089  -18.385 1    103.25 ? 185 GLN A O   1 -0.225 0.23   -0.046 
ATOM   1292  C  CB  . GLN A 1 196 ? -27.455 24.397  -18.532 1    97.02  ? 185 GLN A CB  1 -0.252 0.224  -0.046 
ATOM   1293  C  CG  . GLN A 1 196 ? -28.509 24.403  -17.44  1    102.18 ? 185 GLN A CG  1 -0.261 0.224  -0.044 
ATOM   1294  C  CD  . GLN A 1 196 ? -29.7   25.223  -17.814 1    106.1  ? 185 GLN A CD  1 -0.272 0.231  -0.044 
ATOM   1295  O  OE1 . GLN A 1 196 ? -29.556 26.295  -18.383 1    107.39 ? 185 GLN A OE1 1 -0.271 0.241  -0.046 
ATOM   1296  N  NE2 . GLN A 1 196 ? -30.891 24.728  -17.507 1    110.14 ? 185 GLN A NE2 1 -0.283 0.227  -0.044 
ATOM   1297  N  N   . MET A 1 197 ? -25.032 24.579  -16.252 1    102.65 ? 186 MET A N   1 -0.229 0.225  -0.041 
ATOM   1298  C  CA  . MET A 1 197 ? -23.933 25.324  -15.653 1    103.99 ? 186 MET A CA  1 -0.219 0.232  -0.039 
ATOM   1299  C  C   . MET A 1 197 ? -23.497 24.615  -14.378 1    107.25 ? 186 MET A C   1 -0.215 0.226  -0.036 
ATOM   1300  O  O   . MET A 1 197 ? -24.119 23.645  -13.931 1    104.03 ? 186 MET A O   1 -0.221 0.217  -0.035 
ATOM   1301  C  CB  . MET A 1 197 ? -24.322 26.774  -15.35  1    100.6  ? 186 MET A CB  1 -0.223 0.245  -0.038 
ATOM   1302  C  CG  . MET A 1 197 ? -25.752 26.918  -14.841 1    111.43 ? 186 MET A CG  1 -0.236 0.247  -0.037 
ATOM   1303  S  SD  . MET A 1 197 ? -26.024 28.37   -13.787 1    117.7  ? 186 MET A SD  1 -0.238 0.26   -0.034 
ATOM   1304  C  CE  . MET A 1 197 ? -25.067 29.557  -14.725 1    116.5  ? 186 MET A CE  1 -0.23  0.271  -0.037 
ATOM   1305  N  N   . GLY A 1 198 ? -22.41  25.106  -13.798 1    104.64 ? 187 GLY A N   1 -0.205 0.23   -0.034 
ATOM   1306  C  CA  . GLY A 1 198 ? -21.987 24.684  -12.481 1    104.81 ? 187 GLY A CA  1 -0.201 0.226  -0.031 
ATOM   1307  C  C   . GLY A 1 198 ? -22.319 25.739  -11.439 1    103.13 ? 187 GLY A C   1 -0.205 0.236  -0.029 
ATOM   1308  O  O   . GLY A 1 198 ? -22.369 26.933  -11.732 1    98.99  ? 187 GLY A O   1 -0.205 0.247  -0.029 
ATOM   1309  N  N   . SER A 1 199 ? -22.538 25.294  -10.206 1    106.48 ? 188 SER A N   1 -0.207 0.232  -0.025 
ATOM   1310  C  CA  . SER A 1 199 ? -22.736 26.253  -9.132  1    105.57 ? 188 SER A CA  1 -0.208 0.241  -0.023 
ATOM   1311  C  C   . SER A 1 199 ? -22.272 25.657  -7.817  1    104.59 ? 188 SER A C   1 -0.204 0.235  -0.02  
ATOM   1312  O  O   . SER A 1 199 ? -22.303 24.435  -7.621  1    100.37 ? 188 SER A O   1 -0.204 0.224  -0.019 
ATOM   1313  C  CB  . SER A 1 199 ? -24.197 26.689  -9.018  1    102.41 ? 188 SER A CB  1 -0.222 0.245  -0.023 
ATOM   1314  O  OG  . SER A 1 199 ? -25.003 25.611  -8.589  1    104.04 ? 188 SER A OG  1 -0.229 0.235  -0.021 
ATOM   1315  N  N   . GLY A 1 200 ? -21.831 26.549  -6.924  1    111.23 ? 189 GLY A N   1 -0.2   0.243  -0.017 
ATOM   1316  C  CA  . GLY A 1 200 ? -21.538 26.222  -5.543  1    108.23 ? 189 GLY A CA  1 -0.197 0.24   -0.014 
ATOM   1317  C  C   . GLY A 1 200 ? -20.785 24.927  -5.321  1    105.22 ? 189 GLY A C   1 -0.19  0.228  -0.013 
ATOM   1318  O  O   . GLY A 1 200 ? -21.355 23.948  -4.821  1    103.95 ? 189 GLY A O   1 -0.196 0.219  -0.012 
ATOM   1319  N  N   . PHE A 1 201 ? -19.505 24.92   -5.691  1    102.51 ? 190 PHE A N   1 -0.179 0.228  -0.014 
ATOM   1320  C  CA  . PHE A 1 201 ? -18.566 23.811  -5.55   1    102.67 ? 190 PHE A CA  1 -0.17  0.218  -0.014 
ATOM   1321  C  C   . PHE A 1 201 ? -18.905 22.604  -6.433  1    100.95 ? 190 PHE A C   1 -0.173 0.207  -0.016 
ATOM   1322  O  O   . PHE A 1 201 ? -18.152 21.624  -6.411  1    103.18 ? 190 PHE A O   1 -0.166 0.198  -0.016 
ATOM   1323  C  CB  . PHE A 1 201 ? -18.431 23.322  -4.093  1    106.49 ? 190 PHE A CB  1 -0.169 0.214  -0.01  
ATOM   1324  C  CG  . PHE A 1 201 ? -18.528 24.421  -3.044  1    110.64 ? 190 PHE A CG  1 -0.17  0.224  -0.008 
ATOM   1325  C  CD1 . PHE A 1 201 ? -17.578 25.433  -2.975  1    113.07 ? 190 PHE A CD1 1 -0.161 0.233  -0.007 
ATOM   1326  C  CD2 . PHE A 1 201 ? -19.553 24.414  -2.105  1    105.71 ? 190 PHE A CD2 1 -0.179 0.224  -0.005 
ATOM   1327  C  CE1 . PHE A 1 201 ? -17.665 26.431  -2      1    111.63 ? 190 PHE A CE1 1 -0.162 0.242  -0.005 
ATOM   1328  C  CE2 . PHE A 1 201 ? -19.642 25.411  -1.137  1    107.52 ? 190 PHE A CE2 1 -0.18  0.233  -0.003 
ATOM   1329  C  CZ  . PHE A 1 201 ? -18.698 26.42   -1.088  1    105.47 ? 190 PHE A CZ  1 -0.171 0.242  -0.003 
ATOM   1330  N  N   . CYS A 1 202 ? -19.983 22.636  -7.217  1    99.86  ? 191 CYS A N   1 -0.183 0.207  -0.018 
ATOM   1331  C  CA  . CYS A 1 202 ? -20.408 21.484  -8.016  1    105.27 ? 191 CYS A CA  1 -0.187 0.197  -0.02  
ATOM   1332  C  C   . CYS A 1 202 ? -20.187 21.71   -9.512  1    98.04  ? 191 CYS A C   1 -0.185 0.199  -0.024 
ATOM   1333  O  O   . CYS A 1 202 ? -20.455 22.799  -10.032 1    99.19  ? 191 CYS A O   1 -0.187 0.209  -0.025 
ATOM   1334  C  CB  . CYS A 1 202 ? -21.881 21.169  -7.752  1    102.68 ? 191 CYS A CB  1 -0.201 0.194  -0.019 
ATOM   1335  S  SG  . CYS A 1 202 ? -22.174 20.601  -6.083  1    100.16 ? 191 CYS A SG  1 -0.203 0.189  -0.015 
ATOM   1336  N  N   . LEU A 1 203 ? -19.702 20.678  -10.201 1    94.85  ? 192 LEU A N   1 -0.181 0.189  -0.025 
ATOM   1337  C  CA  . LEU A 1 203 ? -19.369 20.768  -11.631 1    97.05  ? 192 LEU A CA  1 -0.178 0.19   -0.029 
ATOM   1338  C  C   . LEU A 1 203 ? -20.248 19.895  -12.518 1    91.63  ? 192 LEU A C   1 -0.186 0.182  -0.031 
ATOM   1339  O  O   . LEU A 1 203 ? -20.638 20.322  -13.601 1    96.64  ? 192 LEU A O   1 -0.189 0.186  -0.034 
ATOM   1340  C  CB  . LEU A 1 203 ? -17.892 20.39   -11.875 1    82.94  ? 192 LEU A CB  1 -0.164 0.187  -0.03  
ATOM   1341  C  CG  . LEU A 1 203 ? -16.839 21.453  -11.56  1    74.07  ? 192 LEU A CG  1 -0.154 0.197  -0.029 
ATOM   1342  C  CD1 . LEU A 1 203 ? -17.315 22.797  -12.071 1    80.92  ? 192 LEU A CD1 1 -0.159 0.209  -0.03  
ATOM   1343  C  CD2 . LEU A 1 203 ? -16.572 21.54   -10.069 1    111.17 ? 192 LEU A CD2 1 -0.152 0.197  -0.025 
ATOM   1344  N  N   . ILE A 1 204 ? -20.564 18.673  -12.083 1    88.12  ? 193 ILE A N   1 -0.188 0.171  -0.03  
ATOM   1345  C  CA  . ILE A 1 204 ? -21.534 17.813  -12.744 1    85.05  ? 193 ILE A CA  1 -0.197 0.163  -0.032 
ATOM   1346  C  C   . ILE A 1 204 ? -22.35  17.093  -11.681 1    91.79  ? 193 ILE A C   1 -0.205 0.157  -0.029 
ATOM   1347  O  O   . ILE A 1 204 ? -21.995 17.07   -10.5   1    98.38  ? 193 ILE A O   1 -0.202 0.156  -0.026 
ATOM   1348  C  CB  . ILE A 1 204 ? -20.853 16.803  -13.666 1    90.72  ? 193 ILE A CB  1 -0.191 0.154  -0.034 
ATOM   1349  C  CG1 . ILE A 1 204 ? -19.674 16.211  -12.928 1    83.9   ? 193 ILE A CG1 1 -0.18  0.149  -0.032 
ATOM   1350  C  CG2 . ILE A 1 204 ? -20.417 17.473  -15.002 1    93.18  ? 193 ILE A CG2 1 -0.187 0.16   -0.037 
ATOM   1351  C  CD1 . ILE A 1 204 ? -18.994 15.099  -13.651 1    86.14  ? 193 ILE A CD1 1 -0.174 0.138  -0.034 
ATOM   1352  N  N   . ASN A 1 205 ? -23.468 16.519  -12.102 1    90.62  ? 194 ASN A N   1 -0.215 0.151  -0.03  
ATOM   1353  C  CA  . ASN A 1 205 ? -24.456 15.975  -11.177 1    88.62  ? 194 ASN A CA  1 -0.224 0.146  -0.028 
ATOM   1354  C  C   . ASN A 1 205 ? -24.367 14.459  -11.255 1    90.85  ? 194 ASN A C   1 -0.223 0.133  -0.028 
ATOM   1355  O  O   . ASN A 1 205 ? -25.198 13.794  -11.88  1    90.69  ? 194 ASN A O   1 -0.231 0.126  -0.03  
ATOM   1356  C  CB  . ASN A 1 205 ? -25.833 16.464  -11.489 1    89.32  ? 194 ASN A CB  1 -0.237 0.151  -0.029 
ATOM   1357  C  CG  . ASN A 1 205 ? -26.712 16.531  -10.263 1    101.07 ? 194 ASN A CG  1 -0.245 0.151  -0.026 
ATOM   1358  O  OD1 . ASN A 1 205 ? -26.91  15.535  -9.561  1    104.71 ? 194 ASN A OD1 1 -0.247 0.142  -0.024 
ATOM   1359  N  ND2 . ASN A 1 205 ? -27.234 17.723  -9.979  1    102.28 ? 194 ASN A ND2 1 -0.25  0.162  -0.025 
ATOM   1360  N  N   . LYS A 1 206 ? -23.338 13.919  -10.589 1    95.01  ? 195 LYS A N   1 -0.214 0.128  -0.026 
ATOM   1361  C  CA  . LYS A 1 206 ? -23.084 12.48   -10.565 1    94.46  ? 195 LYS A CA  1 -0.212 0.114  -0.026 
ATOM   1362  C  C   . LYS A 1 206 ? -24.291 11.688  -10.073 1    92.81  ? 195 LYS A C   1 -0.223 0.107  -0.025 
ATOM   1363  O  O   . LYS A 1 206 ? -24.453 10.513  -10.434 1    89.05  ? 195 LYS A O   1 -0.224 0.096  -0.026 
ATOM   1364  C  CB  . LYS A 1 206 ? -21.862 12.184  -9.684  1    86.17  ? 195 LYS A CB  1 -0.2   0.112  -0.024 
ATOM   1365  C  CG  . LYS A 1 206 ? -21.477 10.728  -9.657  1    90.24  ? 195 LYS A CG  1 -0.197 0.098  -0.024 
ATOM   1366  C  CD  . LYS A 1 206 ? -20.282 10.498  -8.776  1    97.12  ? 195 LYS A CD  1 -0.186 0.096  -0.022 
ATOM   1367  C  CE  . LYS A 1 206 ? -20.241 9.052   -8.338  1    100.06 ? 195 LYS A CE  1 -0.185 0.083  -0.021 
ATOM   1368  N  NZ  . LYS A 1 206 ? -19.292 8.85    -7.23   1    101.55 ? 195 LYS A NZ  1 -0.177 0.081  -0.018 
ATOM   1369  N  N   . THR A 1 207 ? -25.157 12.301  -9.265  1    92.15  ? 196 THR A N   1 -0.231 0.113  -0.023 
ATOM   1370  C  CA  . THR A 1 207 ? -26.325 11.567  -8.794  1    96.65  ? 196 THR A CA  1 -0.241 0.106  -0.022 
ATOM   1371  C  C   . THR A 1 207 ? -27.298 11.284  -9.927  1    96.48  ? 196 THR A C   1 -0.25  0.103  -0.025 
ATOM   1372  O  O   . THR A 1 207 ? -27.815 10.165  -10.046 1    99.74  ? 196 THR A O   1 -0.255 0.093  -0.025 
ATOM   1373  C  CB  . THR A 1 207 ? -27.044 12.324  -7.693  1    96.51  ? 196 THR A CB  1 -0.248 0.113  -0.019 
ATOM   1374  O  OG1 . THR A 1 207 ? -26.117 12.703  -6.675  1    102.22 ? 196 THR A OG1 1 -0.239 0.116  -0.017 
ATOM   1375  C  CG2 . THR A 1 207 ? -28.103 11.429  -7.1    1    95.18  ? 196 THR A CG2 1 -0.258 0.105  -0.018 
ATOM   1376  N  N   . ALA A 1 208 ? -27.588 12.299  -10.751 1    100.23 ? 197 ALA A N   1 -0.253 0.113  -0.027 
ATOM   1377  C  CA  . ALA A 1 208 ? -28.563 12.126  -11.828 1    95.82  ? 197 ALA A CA  1 -0.262 0.111  -0.03  
ATOM   1378  C  C   . ALA A 1 208 ? -28.071 11.095  -12.845 1    93.44  ? 197 ALA A C   1 -0.257 0.102  -0.032 
ATOM   1379  O  O   . ALA A 1 208 ? -28.813 10.184  -13.235 1    91.35  ? 197 ALA A O   1 -0.264 0.093  -0.033 
ATOM   1380  C  CB  . ALA A 1 208 ? -28.86  13.479  -12.479 1    81.82  ? 197 ALA A CB  1 -0.264 0.124  -0.031 
ATOM   1381  N  N   . MET A 1 209 ? -26.803 11.192  -13.245 1    89.19  ? 198 MET A N   1 -0.246 0.103  -0.033 
ATOM   1382  C  CA  . MET A 1 209 ? -26.236 10.173  -14.117 1    89.6   ? 198 MET A CA  1 -0.24  0.093  -0.035 
ATOM   1383  C  C   . MET A 1 209 ? -26.38  8.782   -13.521 1    89.94  ? 198 MET A C   1 -0.242 0.08   -0.034 
ATOM   1384  O  O   . MET A 1 209 ? -26.695 7.825   -14.233 1    92.26  ? 198 MET A O   1 -0.245 0.072  -0.036 
ATOM   1385  C  CB  . MET A 1 209 ? -24.773 10.477  -14.38  1    87.11  ? 198 MET A CB  1 -0.227 0.096  -0.036 
ATOM   1386  C  CG  . MET A 1 209 ? -24.5   11.936  -14.643 1    90.65  ? 198 MET A CG  1 -0.225 0.109  -0.037 
ATOM   1387  S  SD  . MET A 1 209 ? -22.765 12.083  -15.21  1    91.67  ? 198 MET A SD  1 -0.209 0.111  -0.038 
ATOM   1388  C  CE  . MET A 1 209 ? -21.91  11.164  -13.891 1    109.9  ? 198 MET A CE  1 -0.201 0.102  -0.035 
ATOM   1389  N  N   . LEU A 1 210 ? -26.163 8.648   -12.211 1    101.46 ? 199 LEU A N   1 -0.24  0.079  -0.03  
ATOM   1390  C  CA  . LEU A 1 210 ? -26.314 7.338   -11.591 1    95.41  ? 199 LEU A CA  1 -0.241 0.067  -0.029 
ATOM   1391  C  C   . LEU A 1 210 ? -27.75  6.855   -11.695 1    97.32  ? 199 LEU A C   1 -0.254 0.063  -0.029 
ATOM   1392  O  O   . LEU A 1 210 ? -27.988 5.652   -11.869 1    95.54  ? 199 LEU A O   1 -0.256 0.052  -0.03  
ATOM   1393  C  CB  . LEU A 1 210 ? -25.866 7.389   -10.143 1    95.04  ? 199 LEU A CB  1 -0.237 0.068  -0.025 
ATOM   1394  C  CG  . LEU A 1 210 ? -24.366 7.451   -9.862  1    95.44  ? 199 LEU A CG  1 -0.223 0.068  -0.025 
ATOM   1395  C  CD1 . LEU A 1 210 ? -24.182 6.935   -8.445  1    99.2   ? 199 LEU A CD1 1 -0.222 0.064  -0.021 
ATOM   1396  C  CD2 . LEU A 1 210 ? -23.549 6.637   -10.837 1    89.57  ? 199 LEU A CD2 1 -0.216 0.061  -0.027 
ATOM   1397  N  N   . MET A 1 211 ? -28.716 7.782   -11.619 1    99.7   ? 200 MET A N   1 -0.263 0.071  -0.029 
ATOM   1398  C  CA  . MET A 1 211 ? -30.106 7.441   -11.909 1    102.43 ? 200 MET A CA  1 -0.276 0.068  -0.03  
ATOM   1399  C  C   . MET A 1 211 ? -30.292 7.085   -13.374 1    103.61 ? 200 MET A C   1 -0.278 0.065  -0.033 
ATOM   1400  O  O   . MET A 1 211 ? -31.156 6.263   -13.704 1    107.47 ? 200 MET A O   1 -0.286 0.057  -0.034 
ATOM   1401  C  CB  . MET A 1 211 ? -31.049 8.597   -11.551 1    100.96 ? 200 MET A CB  1 -0.285 0.079  -0.029 
ATOM   1402  C  CG  . MET A 1 211 ? -31.542 8.588   -10.128 1    100.6  ? 200 MET A CG  1 -0.289 0.079  -0.025 
ATOM   1403  S  SD  . MET A 1 211 ? -31.951 10.179  -9.445  1    96.3   ? 200 MET A SD  1 -0.293 0.093  -0.024 
ATOM   1404  C  CE  . MET A 1 211 ? -33.554 10.429  -10.165 1    85.27  ? 200 MET A CE  1 -0.307 0.096  -0.025 
ATOM   1405  N  N   . LYS A 1 212 ? -29.533 7.715   -14.268 1    98.95  ? 201 LYS A N   1 -0.271 0.071  -0.036 
ATOM   1406  C  CA  . LYS A 1 212 ? -29.667 7.369   -15.677 1    105.28 ? 201 LYS A CA  1 -0.272 0.068  -0.039 
ATOM   1407  C  C   . LYS A 1 212 ? -29.328 5.9     -15.883 1    105.59 ? 201 LYS A C   1 -0.269 0.054  -0.04  
ATOM   1408  O  O   . LYS A 1 212 ? -30.164 5.115   -16.348 1    107.19 ? 201 LYS A O   1 -0.276 0.047  -0.041 
ATOM   1409  C  CB  . LYS A 1 212 ? -28.784 8.27    -16.549 1    103.41 ? 201 LYS A CB  1 -0.264 0.076  -0.041 
ATOM   1410  C  CG  . LYS A 1 212 ? -29.085 8.169   -18.036 1    106.35 ? 201 LYS A CG  1 -0.267 0.075  -0.045 
ATOM   1411  C  CD  . LYS A 1 212 ? -30.532 8.552   -18.287 1    107.16 ? 201 LYS A CD  1 -0.28  0.078  -0.046 
ATOM   1412  C  CE  . LYS A 1 212 ? -31.021 8.068   -19.625 1    104.53 ? 201 LYS A CE  1 -0.284 0.074  -0.049 
ATOM   1413  N  NZ  . LYS A 1 212 ? -32.459 8.436   -19.729 1    112.17 ? 201 LYS A NZ  1 -0.297 0.077  -0.049 
ATOM   1414  N  N   . GLN A 1 213 ? -28.123 5.498   -15.461 1    100.63 ? 202 GLN A N   1 -0.258 0.05   -0.039 
ATOM   1415  C  CA  . GLN A 1 213 ? -27.685 4.121   -15.64  1    101.41 ? 202 GLN A CA  1 -0.254 0.038  -0.039 
ATOM   1416  C  C   . GLN A 1 213 ? -28.598 3.127   -14.939 1    104.01 ? 202 GLN A C   1 -0.262 0.029  -0.037 
ATOM   1417  O  O   . GLN A 1 213 ? -28.478 1.927   -15.187 1    105.08 ? 202 GLN A O   1 -0.261 0.018  -0.038 
ATOM   1418  C  CB  . GLN A 1 213 ? -26.236 3.965   -15.16  1    92.17  ? 202 GLN A CB  1 -0.24  0.036  -0.038 
ATOM   1419  C  CG  . GLN A 1 213 ? -25.517 2.689   -15.628 1    97.39  ? 202 GLN A CG  1 -0.234 0.025  -0.039 
ATOM   1420  C  CD  . GLN A 1 213 ? -25.593 2.435   -17.153 1    115.53 ? 202 GLN A CD  1 -0.235 0.022  -0.043 
ATOM   1421  O  OE1 . GLN A 1 213 ? -25.677 1.276   -17.573 1    121.71 ? 202 GLN A OE1 1 -0.235 0.012  -0.044 
ATOM   1422  N  NE2 . GLN A 1 213 ? -25.539 3.505   -17.983 1    101.85 ? 202 GLN A NE2 1 -0.234 0.032  -0.045 
ATOM   1423  N  N   . ALA A 1 214 ? -29.522 3.588   -14.099 1    103.05 ? 203 ALA A N   1 -0.271 0.033  -0.035 
ATOM   1424  C  CA  . ALA A 1 214 ? -30.478 2.691   -13.466 1    106.24 ? 203 ALA A CA  1 -0.279 0.025  -0.034 
ATOM   1425  C  C   . ALA A 1 214 ? -31.743 2.528   -14.296 1    104.4  ? 203 ALA A C   1 -0.291 0.023  -0.036 
ATOM   1426  O  O   . ALA A 1 214 ? -32.289 1.424   -14.383 1    107.9  ? 203 ALA A O   1 -0.296 0.013  -0.036 
ATOM   1427  C  CB  . ALA A 1 214 ? -30.827 3.198   -12.061 1    108.58 ? 203 ALA A CB  1 -0.283 0.029  -0.03  
ATOM   1428  N  N   . GLU A 1 215 ? -32.224 3.614   -14.902 1    106.47 ? 204 GLU A N   1 -0.295 0.033  -0.037 
ATOM   1429  C  CA  . GLU A 1 215 ? -33.348 3.512   -15.828 1    115.16 ? 204 GLU A CA  1 -0.306 0.032  -0.04  
ATOM   1430  C  C   . GLU A 1 215 ? -33.019 2.586   -17.003 1    118.27 ? 204 GLU A C   1 -0.303 0.024  -0.042 
ATOM   1431  O  O   . GLU A 1 215 ? -33.875 1.808   -17.447 1    120.29 ? 204 GLU A O   1 -0.31  0.017  -0.044 
ATOM   1432  C  CB  . GLU A 1 215 ? -33.73  4.91    -16.319 1    114.27 ? 204 GLU A CB  1 -0.309 0.045  -0.041 
ATOM   1433  C  CG  . GLU A 1 215 ? -34.91  4.958   -17.283 1    121.88 ? 204 GLU A CG  1 -0.32  0.045  -0.043 
ATOM   1434  C  CD  . GLU A 1 215 ? -34.892 6.208   -18.159 1    122.26 ? 204 GLU A CD  1 -0.32  0.057  -0.045 
ATOM   1435  O  OE1 . GLU A 1 215 ? -33.801 6.807   -18.312 1    118.1  ? 204 GLU A OE1 1 -0.31  0.062  -0.046 
ATOM   1436  O  OE2 . GLU A 1 215 ? -35.965 6.59    -18.69  1    126.18 ? 204 GLU A OE2 1 -0.33  0.06   -0.047 
ATOM   1437  N  N   . LEU A 1 216 ? -31.774 2.631   -17.499 1    111.95 ? 205 LEU A N   1 -0.291 0.024  -0.044 
ATOM   1438  C  CA  . LEU A 1 216 ? -31.376 1.87    -18.682 1    112.04 ? 205 LEU A CA  1 -0.288 0.017  -0.047 
ATOM   1439  C  C   . LEU A 1 216 ? -30.854 0.47    -18.37  1    115.7  ? 205 LEU A C   1 -0.283 0.004  -0.046 
ATOM   1440  O  O   . LEU A 1 216 ? -30.997 -0.424  -19.211 1    129.54 ? 205 LEU A O   1 -0.284 -0.004 -0.048 
ATOM   1441  C  CB  . LEU A 1 216 ? -30.31  2.633   -19.476 1    106.95 ? 205 LEU A CB  1 -0.278 0.024  -0.049 
ATOM   1442  C  CG  . LEU A 1 216 ? -30.533 4.137   -19.65  1    106.52 ? 205 LEU A CG  1 -0.28  0.038  -0.049 
ATOM   1443  C  CD1 . LEU A 1 216 ? -29.481 4.676   -20.545 1    93.54  ? 205 LEU A CD1 1 -0.27  0.043  -0.051 
ATOM   1444  C  CD2 . LEU A 1 216 ? -31.92  4.478   -20.184 1    105.24 ? 205 LEU A CD2 1 -0.293 0.041  -0.05  
ATOM   1445  N  N   . SER A 1 217 ? -30.228 0.252   -17.208 1    114.52 ? 206 SER A N   1 -0.277 0.002  -0.043 
ATOM   1446  C  CA  . SER A 1 217 ? -29.738 -1.079  -16.851 1    116.6  ? 206 SER A CA  1 -0.273 -0.01  -0.042 
ATOM   1447  C  C   . SER A 1 217 ? -30.855 -2.023  -16.453 1    122.72 ? 206 SER A C   1 -0.283 -0.019 -0.041 
ATOM   1448  O  O   . SER A 1 217 ? -30.665 -3.242  -16.493 1    121.08 ? 206 SER A O   1 -0.281 -0.03  -0.041 
ATOM   1449  C  CB  . SER A 1 217 ? -28.76  -1.025  -15.675 1    119.48 ? 206 SER A CB  1 -0.264 -0.009 -0.039 
ATOM   1450  O  OG  . SER A 1 217 ? -27.836 0.043   -15.788 1    119.83 ? 206 SER A OG  1 -0.255 0.0    -0.039 
ATOM   1451  N  N   . SER A 1 218 ? -31.986 -1.485  -16.019 1    128.61 ? 207 SER A N   1 -0.293 -0.014 -0.04  
ATOM   1452  C  CA  . SER A 1 218 ? -33.117 -2.286  -15.586 1    131.29 ? 207 SER A CA  1 -0.303 -0.021 -0.039 
ATOM   1453  C  C   . SER A 1 218 ? -34.078 -2.5    -16.754 1    130.32 ? 207 SER A C   1 -0.312 -0.023 -0.042 
ATOM   1454  O  O   . SER A 1 218 ? -34.127 -1.706  -17.703 1    124.66 ? 207 SER A O   1 -0.313 -0.016 -0.044 
ATOM   1455  C  CB  . SER A 1 218 ? -33.831 -1.61   -14.408 1    122.53 ? 207 SER A CB  1 -0.31  -0.015 -0.036 
ATOM   1456  O  OG  . SER A 1 218 ? -34.937 -2.37   -13.949 1    125.05 ? 207 SER A OG  1 -0.32  -0.022 -0.035 
ATOM   1457  N  N   . ALA A 1 219 ? -34.827 -3.603  -16.682 1    130.46 ? 208 ALA A N   1 -0.319 -0.033 -0.042 
ATOM   1458  C  CA  . ALA A 1 219 ? -35.858 -3.884  -17.675 1    133.48 ? 208 ALA A CA  1 -0.329 -0.036 -0.044 
ATOM   1459  C  C   . ALA A 1 219 ? -37     -2.878  -17.576 1    136.74 ? 208 ALA A C   1 -0.339 -0.026 -0.044 
ATOM   1460  O  O   . ALA A 1 219 ? -37.34  -2.196  -18.554 1    141.58 ? 208 ALA A O   1 -0.342 -0.02  -0.046 
ATOM   1461  C  CB  . ALA A 1 219 ? -36.374 -5.311  -17.489 1    135.8  ? 208 ALA A CB  1 -0.333 -0.049 -0.044 
ATOM   1462  N  N   . GLN A 1 220 ? -37.622 -2.795  -16.4   1    132.46 ? 209 GLN A N   1 -0.345 -0.026 -0.041 
ATOM   1463  C  CA  . GLN A 1 220 ? -38.614 -1.786  -16.076 1    134.22 ? 209 GLN A CA  1 -0.354 -0.016 -0.04  
ATOM   1464  C  C   . GLN A 1 220 ? -38.005 -0.787  -15.106 1    132.71 ? 209 GLN A C   1 -0.348 -0.007 -0.038 
ATOM   1465  O  O   . GLN A 1 220 ? -37.393 -1.201  -14.11  1    128.6  ? 209 GLN A O   1 -0.343 -0.011 -0.035 
ATOM   1466  C  CB  . GLN A 1 220 ? -39.859 -2.431  -15.453 1    139.72 ? 209 GLN A CB  1 -0.365 -0.022 -0.039 
ATOM   1467  C  CG  . GLN A 1 220 ? -40.47  -3.554  -16.283 1    130.3  ? 209 GLN A CG  1 -0.371 -0.033 -0.041 
ATOM   1468  C  CD  . GLN A 1 220 ? -41.674 -3.1    -17.091 1    133.72 ? 209 GLN A CD  1 -0.382 -0.028 -0.043 
ATOM   1469  O  OE1 . GLN A 1 220 ? -41.767 -1.935  -17.503 1    127.92 ? 209 GLN A OE1 1 -0.383 -0.018 -0.044 
ATOM   1470  N  NE2 . GLN A 1 220 ? -42.61  -4.023  -17.321 1    134.97 ? 209 GLN A NE2 1 -0.39  -0.037 -0.043 
ATOM   1471  N  N   . PRO A 1 221 ? -38.138 0.513   -15.363 1    133.22 ? 210 PRO A N   1 -0.35  0.005  -0.038 
ATOM   1472  C  CA  . PRO A 1 221 ? -37.481 1.526   -14.519 1    131.26 ? 210 PRO A CA  1 -0.343 0.014  -0.036 
ATOM   1473  C  C   . PRO A 1 221 ? -37.783 1.32    -13.046 1    124.48 ? 210 PRO A C   1 -0.346 0.012  -0.033 
ATOM   1474  O  O   . PRO A 1 221 ? -38.932 1.048   -12.665 1    123.95 ? 210 PRO A O   1 -0.357 0.01   -0.032 
ATOM   1475  C  CB  . PRO A 1 221 ? -38.077 2.844   -15.034 1    133.93 ? 210 PRO A CB  1 -0.349 0.026  -0.038 
ATOM   1476  C  CG  . PRO A 1 221 ? -38.321 2.565   -16.496 1    133.97 ? 210 PRO A CG  1 -0.351 0.024  -0.041 
ATOM   1477  C  CD  . PRO A 1 221 ? -38.779 1.117   -16.548 1    134.97 ? 210 PRO A CD  1 -0.355 0.01   -0.041 
ATOM   1478  N  N   . PRO A 1 222 ? -36.769 1.414   -12.189 1    120.1  ? 211 PRO A N   1 -0.337 0.013  -0.03  
ATOM   1479  C  CA  . PRO A 1 222 ? -37.01  1.284   -10.753 1    118.42 ? 211 PRO A CA  1 -0.339 0.012  -0.027 
ATOM   1480  C  C   . PRO A 1 222 ? -37.716 2.513   -10.202 1    115.46 ? 211 PRO A C   1 -0.346 0.023  -0.025 
ATOM   1481  O  O   . PRO A 1 222 ? -37.615 3.616   -10.753 1    110.36 ? 211 PRO A O   1 -0.345 0.033  -0.027 
ATOM   1482  C  CB  . PRO A 1 222 ? -35.6   1.144   -10.169 1    113.02 ? 211 PRO A CB  1 -0.326 0.01   -0.025 
ATOM   1483  C  CG  . PRO A 1 222 ? -34.74  1.884   -11.123 1    111.4  ? 211 PRO A CG  1 -0.318 0.017  -0.028 
ATOM   1484  C  CD  . PRO A 1 222 ? -35.342 1.629   -12.486 1    118.36 ? 211 PRO A CD  1 -0.324 0.015  -0.031 
ATOM   1485  N  N   . LYS A 1 223 ? -38.451 2.301   -9.105  1    116.15 ? 212 LYS A N   1 -0.352 0.021  -0.023 
ATOM   1486  C  CA  . LYS A 1 223 ? -39.103 3.395   -8.399  1    114.23 ? 212 LYS A CA  1 -0.358 0.031  -0.021 
ATOM   1487  C  C   . LYS A 1 223 ? -38.041 4.156   -7.61   1    108.59 ? 212 LYS A C   1 -0.349 0.038  -0.019 
ATOM   1488  O  O   . LYS A 1 223 ? -37.379 3.586   -6.738  1    108.71 ? 212 LYS A O   1 -0.343 0.033  -0.017 
ATOM   1489  C  CB  . LYS A 1 223 ? -40.219 2.869   -7.491  1    106.75 ? 212 LYS A CB  1 -0.369 0.026  -0.019 
ATOM   1490  C  CG  . LYS A 1 223 ? -41.151 3.956   -6.938  1    112.3  ? 212 LYS A CG  1 -0.377 0.036  -0.017 
ATOM   1491  C  CD  . LYS A 1 223 ? -42.16  3.355   -5.935  1    138.01 ? 212 LYS A CD  1 -0.386 0.031  -0.015 
ATOM   1492  C  CE  . LYS A 1 223 ? -43.033 4.407   -5.222  1    141.06 ? 212 LYS A CE  1 -0.394 0.04   -0.013 
ATOM   1493  N  NZ  . LYS A 1 223 ? -42.371 5.106   -4.07   1    130.4  ? 212 LYS A NZ  1 -0.388 0.047  -0.01  
ATOM   1494  N  N   . PHE A 1 224 ? -37.843 5.423   -7.961  1    108.66 ? 213 PHE A N   1 -0.347 0.05   -0.02  
ATOM   1495  C  CA  . PHE A 1 224 ? -36.756 6.214   -7.411  1    103.21 ? 213 PHE A CA  1 -0.337 0.057  -0.019 
ATOM   1496  C  C   . PHE A 1 224 ? -37.203 6.951   -6.159  1    109.46 ? 213 PHE A C   1 -0.341 0.064  -0.015 
ATOM   1497  O  O   . PHE A 1 224 ? -38.357 7.379   -6.036  1    107.17 ? 213 PHE A O   1 -0.352 0.068  -0.015 
ATOM   1498  C  CB  . PHE A 1 224 ? -36.226 7.215   -8.438  1    103.88 ? 213 PHE A CB  1 -0.332 0.066  -0.021 
ATOM   1499  C  CG  . PHE A 1 224 ? -35.413 6.584   -9.522  1    108.43 ? 213 PHE A CG  1 -0.325 0.06   -0.024 
ATOM   1500  C  CD1 . PHE A 1 224 ? -34.085 6.252   -9.31   1    107.92 ? 213 PHE A CD1 1 -0.312 0.057  -0.023 
ATOM   1501  C  CD2 . PHE A 1 224 ? -35.976 6.303   -10.746 1    106.82 ? 213 PHE A CD2 1 -0.33  0.058  -0.027 
ATOM   1502  C  CE1 . PHE A 1 224 ? -33.342 5.657   -10.304 1    104.48 ? 213 PHE A CE1 1 -0.306 0.052  -0.026 
ATOM   1503  C  CE2 . PHE A 1 224 ? -35.236 5.719   -11.729 1    105.13 ? 213 PHE A CE2 1 -0.323 0.052  -0.029 
ATOM   1504  C  CZ  . PHE A 1 224 ? -33.919 5.4     -11.512 1    104.65 ? 213 PHE A CZ  1 -0.311 0.049  -0.029 
ATOM   1505  N  N   . VAL A 1 225 ? -36.264 7.08    -5.225  1    112.17 ? 214 VAL A N   1 -0.332 0.065  -0.013 
ATOM   1506  C  CA  . VAL A 1 225 ? -36.437 7.819   -3.986  1    102.62 ? 214 VAL A CA  1 -0.334 0.072  -0.01  
ATOM   1507  C  C   . VAL A 1 225 ? -35.105 8.466   -3.637  1    100.66 ? 214 VAL A C   1 -0.322 0.078  -0.009 
ATOM   1508  O  O   . VAL A 1 225 ? -34.071 7.794   -3.599  1    101.02 ? 214 VAL A O   1 -0.312 0.071  -0.009 
ATOM   1509  C  CB  . VAL A 1 225 ? -36.94  6.898   -2.855  1    109.93 ? 214 VAL A CB  1 -0.339 0.063  -0.007 
ATOM   1510  C  CG1 . VAL A 1 225 ? -36.6   7.491   -1.476  1    101.76 ? 214 VAL A CG1 1 -0.335 0.069  -0.004 
ATOM   1511  C  CG2 . VAL A 1 225 ? -38.444 6.669   -3.008  1    112.2  ? 214 VAL A CG2 1 -0.352 0.061  -0.008 
ATOM   1512  N  N   . ILE A 1 226 ? -35.12  9.773   -3.404  1    99.12  ? 215 ILE A N   1 -0.322 0.09   -0.008 
ATOM   1513  C  CA  . ILE A 1 226 ? -33.927 10.5    -2.994  1    103.77 ? 215 ILE A CA  1 -0.311 0.096  -0.007 
ATOM   1514  C  C   . ILE A 1 226 ? -34.196 11.193  -1.657  1    106.86 ? 215 ILE A C   1 -0.313 0.103  -0.004 
ATOM   1515  O  O   . ILE A 1 226 ? -35.299 11.693  -1.418  1    109.74 ? 215 ILE A O   1 -0.323 0.107  -0.004 
ATOM   1516  C  CB  . ILE A 1 226 ? -33.498 11.507  -4.078  1    102.15 ? 215 ILE A CB  1 -0.307 0.105  -0.01  
ATOM   1517  C  CG1 . ILE A 1 226 ? -33.67  10.89   -5.465  1    103.92 ? 215 ILE A CG1 1 -0.309 0.1    -0.014 
ATOM   1518  C  CG2 . ILE A 1 226 ? -32.04  11.886  -3.911  1    102.93 ? 215 ILE A CG2 1 -0.294 0.109  -0.01  
ATOM   1519  C  CD1 . ILE A 1 226 ? -33.053 11.707  -6.584  1    100.35 ? 215 ILE A CD1 1 -0.303 0.107  -0.016 
ATOM   1520  N  N   . ILE A 1 227 ? -33.198 11.191  -0.773  1    103.59 ? 216 ILE A N   1 -0.304 0.103  -0.002 
ATOM   1521  C  CA  . ILE A 1 227 ? -33.233 11.95   0.476   1    98.37  ? 216 ILE A CA  1 -0.305 0.11   0.001  
ATOM   1522  C  C   . ILE A 1 227 ? -31.905 12.684  0.591   1    98.62  ? 216 ILE A C   1 -0.292 0.116  0.001  
ATOM   1523  O  O   . ILE A 1 227 ? -30.867 12.052  0.829   1    100.37 ? 216 ILE A O   1 -0.283 0.11   0.002  
ATOM   1524  C  CB  . ILE A 1 227 ? -33.447 11.063  1.714   1    98.34  ? 216 ILE A CB  1 -0.307 0.101  0.004  
ATOM   1525  C  CG1 . ILE A 1 227 ? -34.642 10.125  1.544   1    103.15 ? 216 ILE A CG1 1 -0.317 0.093  0.004  
ATOM   1526  C  CG2 . ILE A 1 227 ? -33.655 11.937  2.944   1    100.92 ? 216 ILE A CG2 1 -0.308 0.109  0.007  
ATOM   1527  C  CD1 . ILE A 1 227 ? -34.906 9.247   2.758   1    90.37  ? 216 ILE A CD1 1 -0.32  0.085  0.007  
ATOM   1528  N  N   . GLY A 1 228 ? -31.933 14.009  0.454   1    98.49  ? 217 GLY A N   1 -0.293 0.128  0.001  
ATOM   1529  C  CA  . GLY A 1 228 ? -30.71  14.8    0.503   1    99.73  ? 217 GLY A CA  1 -0.281 0.136  0.001  
ATOM   1530  C  C   . GLY A 1 228 ? -30.629 15.689  1.728   1    97.81  ? 217 GLY A C   1 -0.281 0.144  0.004  
ATOM   1531  O  O   . GLY A 1 228 ? -31.325 16.707  1.819   1    94.66  ? 217 GLY A O   1 -0.287 0.153  0.005  
ATOM   1532  N  N   . THR A 1 229 ? -29.787 15.319  2.69    1    105.28 ? 218 THR A N   1 -0.273 0.14   0.007  
ATOM   1533  C  CA  . THR A 1 229 ? -29.811 15.96   4       1    101.28 ? 218 THR A CA  1 -0.273 0.146  0.01   
ATOM   1534  C  C   . THR A 1 229 ? -28.798 17.091  4.139   1    99.08  ? 218 THR A C   1 -0.264 0.157  0.01   
ATOM   1535  O  O   . THR A 1 229 ? -28.769 17.738  5.19    1    100.4  ? 218 THR A O   1 -0.264 0.163  0.013  
ATOM   1536  C  CB  . THR A 1 229 ? -29.57  14.928  5.096   1    90.36  ? 218 THR A CB  1 -0.271 0.137  0.013  
ATOM   1537  O  OG1 . THR A 1 229 ? -28.171 14.906  5.409   1    95.25  ? 218 THR A OG1 1 -0.258 0.137  0.014  
ATOM   1538  C  CG2 . THR A 1 229 ? -30.005 13.539  4.63    1    88.31  ? 218 THR A CG2 1 -0.275 0.124  0.012  
ATOM   1539  N  N   . ASP A 1 230 ? -27.959 17.326  3.124   1    94.16  ? 219 ASP A N   1 -0.256 0.159  0.008  
ATOM   1540  C  CA  . ASP A 1 230 ? -27.118 18.517  3.07    1    90.59  ? 219 ASP A CA  1 -0.249 0.17   0.008  
ATOM   1541  C  C   . ASP A 1 230 ? -27.973 19.754  3.315   1    94.1   ? 219 ASP A C   1 -0.256 0.181  0.008  
ATOM   1542  O  O   . ASP A 1 230 ? -29.077 19.875  2.788   1    99.34  ? 219 ASP A O   1 -0.266 0.182  0.007  
ATOM   1543  C  CB  . ASP A 1 230 ? -26.424 18.574  1.704   1    95.04  ? 219 ASP A CB  1 -0.242 0.17   0.004  
ATOM   1544  C  CG  . ASP A 1 230 ? -25.515 19.788  1.515   1    93.38  ? 219 ASP A CG  1 -0.234 0.181  0.004  
ATOM   1545  O  OD1 . ASP A 1 230 ? -25.971 20.93   1.74    1    92.62  ? 219 ASP A OD1 1 -0.238 0.192  0.004  
ATOM   1546  O  OD2 . ASP A 1 230 ? -24.352 19.591  1.068   1    94.35  ? 219 ASP A OD2 1 -0.223 0.18   0.003  
ATOM   1547  N  N   . VAL A 1 231 ? -27.468 20.672  4.143   1    96.53  ? 220 VAL A N   1 -0.252 0.189  0.01   
ATOM   1548  C  CA  . VAL A 1 231 ? -28.313 21.764  4.618   1    97.42  ? 220 VAL A CA  1 -0.259 0.199  0.012  
ATOM   1549  C  C   . VAL A 1 231 ? -28.672 22.749  3.503   1    89.9   ? 220 VAL A C   1 -0.263 0.208  0.009  
ATOM   1550  O  O   . VAL A 1 231 ? -29.721 23.398  3.586   1    89.12  ? 220 VAL A O   1 -0.272 0.214  0.009  
ATOM   1551  C  CB  . VAL A 1 231 ? -27.642 22.434  5.849   1    92.07  ? 220 VAL A CB  1 -0.253 0.206  0.015  
ATOM   1552  C  CG1 . VAL A 1 231 ? -26.281 23.14   5.49    1    95.43  ? 220 VAL A CG1 1 -0.241 0.212  0.014  
ATOM   1553  C  CG2 . VAL A 1 231 ? -28.673 23.286  6.667   1    80.31  ? 220 VAL A CG2 1 -0.263 0.213  0.017  
ATOM   1554  N  N   . ASN A 1 232 ? -27.851 22.864  2.461   1    91.55  ? 221 ASN A N   1 -0.255 0.21   0.006  
ATOM   1555  C  CA  . ASN A 1 232 ? -28.179 23.657  1.276   1    103.37 ? 221 ASN A CA  1 -0.258 0.217  0.003  
ATOM   1556  C  C   . ASN A 1 232 ? -29.061 22.875  0.293   1    96.91  ? 221 ASN A C   1 -0.266 0.21   0.001  
ATOM   1557  O  O   . ASN A 1 232 ? -28.879 21.672  0.089   1    94.75  ? 221 ASN A O   1 -0.265 0.199  0.0    
ATOM   1558  C  CB  . ASN A 1 232 ? -26.901 24.106  0.562   1    102.06 ? 221 ASN A CB  1 -0.247 0.221  0.001  
ATOM   1559  C  CG  . ASN A 1 232 ? -25.804 24.491  1.531   1    101.95 ? 221 ASN A CG  1 -0.236 0.224  0.004  
ATOM   1560  O  OD1 . ASN A 1 232 ? -25.086 23.634  2.054   1    99.69  ? 221 ASN A OD1 1 -0.23  0.217  0.005  
ATOM   1561  N  ND2 . ASN A 1 232 ? -25.658 25.785  1.767   1    104.32 ? 221 ASN A ND2 1 -0.235 0.236  0.004  
ATOM   1562  N  N   . ARG A 1 233 ? -30.001 23.587  -0.338  1    96.91  ? 222 ARG A N   1 -0.275 0.216  -0.001 
ATOM   1563  C  CA  . ARG A 1 233 ? -31.028 22.947  -1.161  1    95.62  ? 222 ARG A CA  1 -0.284 0.21   -0.003 
ATOM   1564  C  C   . ARG A 1 233 ? -30.434 22.253  -2.38   1    99.44  ? 222 ARG A C   1 -0.279 0.204  -0.006 
ATOM   1565  O  O   . ARG A 1 233 ? -29.536 22.783  -3.048  1    99.68  ? 222 ARG A O   1 -0.271 0.209  -0.008 
ATOM   1566  C  CB  . ARG A 1 233 ? -32.057 23.975  -1.634  1    91.39  ? 222 ARG A CB  1 -0.294 0.22   -0.004 
ATOM   1567  C  CG  . ARG A 1 233 ? -33.067 23.372  -2.583  1    96.73  ? 222 ARG A CG  1 -0.303 0.214  -0.006 
ATOM   1568  C  CD  . ARG A 1 233 ? -34.27  24.256  -2.84   1    97.86  ? 222 ARG A CD  1 -0.314 0.222  -0.007 
ATOM   1569  N  NE  . ARG A 1 233 ? -35.024 23.75   -3.984  1    105.32 ? 222 ARG A NE  1 -0.321 0.218  -0.01  
ATOM   1570  C  CZ  . ARG A 1 233 ? -35.065 24.332  -5.18   1    105.72 ? 222 ARG A CZ  1 -0.321 0.223  -0.013 
ATOM   1571  N  NH1 . ARG A 1 233 ? -34.441 25.48   -5.416  1    101.51 ? 222 ARG A NH1 1 -0.316 0.234  -0.014 
ATOM   1572  N  NH2 . ARG A 1 233 ? -35.788 23.773  -6.152  1    101.88 ? 222 ARG A NH2 1 -0.328 0.218  -0.015 
ATOM   1573  N  N   . ASP A 1 234 ? -30.964 21.065  -2.691  1    95.18  ? 223 ASP A N   1 -0.284 0.193  -0.007 
ATOM   1574  C  CA  . ASP A 1 234 ? -30.62  20.379  -3.938  1    98.11  ? 223 ASP A CA  1 -0.281 0.187  -0.01  
ATOM   1575  C  C   . ASP A 1 234 ? -31.176 21.129  -5.154  1    100.29 ? 223 ASP A C   1 -0.286 0.194  -0.013 
ATOM   1576  O  O   . ASP A 1 234 ? -31.898 20.54   -5.971  1    95.96  ? 223 ASP A O   1 -0.292 0.188  -0.015 
ATOM   1577  C  CB  . ASP A 1 234 ? -31.168 18.945  -3.96   1    98.51  ? 223 ASP A CB  1 -0.286 0.174  -0.01  
ATOM   1578  C  CG  . ASP A 1 234 ? -30.907 18.182  -2.681  1    99.71  ? 223 ASP A CG  1 -0.283 0.167  -0.007 
ATOM   1579  O  OD1 . ASP A 1 234 ? -29.868 18.428  -2.042  1    109.74 ? 223 ASP A OD1 1 -0.274 0.169  -0.005 
ATOM   1580  O  OD2 . ASP A 1 234 ? -31.74  17.322  -2.313  1    95.8   ? 223 ASP A OD2 1 -0.291 0.159  -0.006 
ATOM   1581  N  N   . ASN A 1 235 ? -30.854 22.421  -5.29   1    99.58  ? 224 ASN A N   1 -0.283 0.205  -0.013 
ATOM   1582  C  CA  . ASN A 1 235 ? -31.471 23.214  -6.345  1    94.84  ? 224 ASN A CA  1 -0.288 0.213  -0.016 
ATOM   1583  C  C   . ASN A 1 235 ? -31.148 22.635  -7.72   1    98.71  ? 224 ASN A C   1 -0.285 0.207  -0.019 
ATOM   1584  O  O   . ASN A 1 235 ? -32.048 22.466  -8.551  1    99.42  ? 224 ASN A O   1 -0.294 0.206  -0.021 
ATOM   1585  C  CB  . ASN A 1 235 ? -31.038 24.682  -6.224  1    93.41  ? 224 ASN A CB  1 -0.284 0.226  -0.016 
ATOM   1586  C  CG  . ASN A 1 235 ? -29.524 24.881  -6.365  1    97.66  ? 224 ASN A CG  1 -0.271 0.228  -0.016 
ATOM   1587  O  OD1 . ASN A 1 235 ? -28.739 23.92   -6.317  1    98.01  ? 224 ASN A OD1 1 -0.263 0.219  -0.016 
ATOM   1588  N  ND2 . ASN A 1 235 ? -29.109 26.143  -6.542  1    94.2   ? 224 ASN A ND2 1 -0.267 0.24   -0.016 
ATOM   1589  N  N   . GLY A 1 236 ? -29.883 22.268  -7.949  1    96.27  ? 225 GLY A N   1 -0.274 0.204  -0.02  
ATOM   1590  C  CA  . GLY A 1 236 ? -29.416 21.776  -9.231  1    93.61  ? 225 GLY A CA  1 -0.27  0.2    -0.023 
ATOM   1591  C  C   . GLY A 1 236 ? -30.078 20.479  -9.636  1    94.32  ? 225 GLY A C   1 -0.276 0.188  -0.024 
ATOM   1592  O  O   . GLY A 1 236 ? -30.95  20.478  -10.502 1    98.88  ? 225 GLY A O   1 -0.284 0.188  -0.026 
ATOM   1593  N  N   . LEU A 1 237 ? -29.689 19.376  -9.001  1    99.49  ? 226 LEU A N   1 -0.272 0.178  -0.022 
ATOM   1594  C  CA  . LEU A 1 237 ? -30.323 18.067  -9.158  1    100.27 ? 226 LEU A CA  1 -0.278 0.166  -0.023 
ATOM   1595  C  C   . LEU A 1 237 ? -31.84  18.151  -9.326  1    101.51 ? 226 LEU A C   1 -0.292 0.166  -0.023 
ATOM   1596  O  O   . LEU A 1 237 ? -32.433 17.347  -10.059 1    103.13 ? 226 LEU A O   1 -0.297 0.159  -0.025 
ATOM   1597  C  CB  . LEU A 1 237 ? -29.987 17.184  -7.954  1    97.48  ? 226 LEU A CB  1 -0.275 0.157  -0.02  
ATOM   1598  C  CG  . LEU A 1 237 ? -30.446 15.73   -7.94   1    97.53  ? 226 LEU A CG  1 -0.279 0.144  -0.02  
ATOM   1599  C  CD1 . LEU A 1 237 ? -29.314 14.899  -7.425  1    100.53 ? 226 LEU A CD1 1 -0.269 0.137  -0.019 
ATOM   1600  C  CD2 . LEU A 1 237 ? -31.652 15.562  -7.036  1    97.61  ? 226 LEU A CD2 1 -0.29  0.143  -0.018 
ATOM   1601  N  N   . CYS A 1 238 ? -32.48  19.117  -8.66   1    101.13 ? 227 CYS A N   1 -0.298 0.175  -0.022 
ATOM   1602  C  CA  . CYS A 1 238 ? -33.92  19.284  -8.832  1    103.97 ? 227 CYS A CA  1 -0.311 0.177  -0.022 
ATOM   1603  C  C   . CYS A 1 238 ? -34.264 19.758  -10.248 1    102.25 ? 227 CYS A C   1 -0.314 0.181  -0.026 
ATOM   1604  O  O   . CYS A 1 238 ? -35.187 19.23   -10.881 1    99.09  ? 227 CYS A O   1 -0.322 0.176  -0.027 
ATOM   1605  C  CB  . CYS A 1 238 ? -34.471 20.255  -7.793  1    98.78  ? 227 CYS A CB  1 -0.316 0.186  -0.019 
ATOM   1606  S  SG  . CYS A 1 238 ? -36.279 20.307  -7.783  1    101.05 ? 227 CYS A SG  1 -0.332 0.186  -0.019 
ATOM   1607  N  N   . ASP A 1 239 ? -33.557 20.775  -10.749 1    99.07  ? 228 ASP A N   1 -0.308 0.19   -0.027 
ATOM   1608  C  CA  . ASP A 1 239 ? -33.831 21.251  -12.097 1    101.57 ? 228 ASP A CA  1 -0.31  0.195  -0.03  
ATOM   1609  C  C   . ASP A 1 239 ? -33.682 20.122  -13.106 1    102.49 ? 228 ASP A C   1 -0.309 0.184  -0.033 
ATOM   1610  O  O   . ASP A 1 239 ? -34.552 19.935  -13.96  1    105.75 ? 228 ASP A O   1 -0.317 0.183  -0.035 
ATOM   1611  C  CB  . ASP A 1 239 ? -32.912 22.42   -12.454 1    103.84 ? 228 ASP A CB  1 -0.302 0.205  -0.031 
ATOM   1612  C  CG  . ASP A 1 239 ? -33.255 23.047  -13.807 1    112.2  ? 228 ASP A CG  1 -0.305 0.211  -0.034 
ATOM   1613  O  OD1 . ASP A 1 239 ? -34.254 23.804  -13.838 1    111.85 ? 228 ASP A OD1 1 -0.314 0.218  -0.035 
ATOM   1614  O  OD2 . ASP A 1 239 ? -32.531 22.792  -14.819 1    104.75 ? 228 ASP A OD2 1 -0.298 0.209  -0.037 
ATOM   1615  N  N   . ILE A 1 240 ? -32.616 19.323  -12.989 1    95.07  ? 229 ILE A N   1 -0.299 0.177  -0.032 
ATOM   1616  C  CA  . ILE A 1 240 ? -32.41  18.22   -13.925 1    95.61  ? 229 ILE A CA  1 -0.297 0.167  -0.035 
ATOM   1617  C  C   . ILE A 1 240 ? -33.522 17.186  -13.832 1    100.46 ? 229 ILE A C   1 -0.307 0.157  -0.035 
ATOM   1618  O  O   . ILE A 1 240 ? -33.797 16.482  -14.81  1    100.17 ? 229 ILE A O   1 -0.31  0.151  -0.037 
ATOM   1619  C  CB  . ILE A 1 240 ? -31.039 17.563  -13.699 1    92.53  ? 229 ILE A CB  1 -0.284 0.161  -0.034 
ATOM   1620  C  CG1 . ILE A 1 240 ? -29.95  18.62   -13.634 1    93.32  ? 229 ILE A CG1 1 -0.274 0.171  -0.034 
ATOM   1621  C  CG2 . ILE A 1 240 ? -30.731 16.556  -14.821 1    97.59  ? 229 ILE A CG2 1 -0.282 0.152  -0.037 
ATOM   1622  C  CD1 . ILE A 1 240 ? -28.655 18.086  -13.054 1    98.33  ? 229 ILE A CD1 1 -0.263 0.166  -0.033 
ATOM   1623  N  N   . LEU A 1 241 ? -34.175 17.054  -12.671 1    103.15 ? 230 LEU A N   1 -0.313 0.156  -0.032 
ATOM   1624  C  CA  . LEU A 1 241 ? -35.235 16.048  -12.592 1    104.6  ? 230 LEU A CA  1 -0.323 0.147  -0.031 
ATOM   1625  C  C   . LEU A 1 241 ? -36.562 16.569  -13.131 1    107.06 ? 230 LEU A C   1 -0.335 0.152  -0.033 
ATOM   1626  O  O   . LEU A 1 241 ? -37.301 15.826  -13.786 1    115.89 ? 230 LEU A O   1 -0.342 0.145  -0.034 
ATOM   1627  C  CB  . LEU A 1 241 ? -35.41  15.541  -11.166 1    98.23  ? 230 LEU A CB  1 -0.325 0.142  -0.028 
ATOM   1628  C  CG  . LEU A 1 241 ? -34.27  14.686  -10.616 1    97.21  ? 230 LEU A CG  1 -0.314 0.135  -0.027 
ATOM   1629  C  CD1 . LEU A 1 241 ? -34.806 13.736  -9.571  1    104.82 ? 230 LEU A CD1 1 -0.319 0.126  -0.024 
ATOM   1630  C  CD2 . LEU A 1 241 ? -33.567 13.927  -11.701 1    98.72  ? 230 LEU A CD2 1 -0.308 0.128  -0.029 
ATOM   1631  N  N   . ARG A 1 242 ? -36.89  17.834  -12.874 1    100    ? 231 ARG A N   1 -0.338 0.163  -0.032 
ATOM   1632  C  CA  . ARG A 1 242 ? -38.027 18.445  -13.556 1    103.7  ? 231 ARG A CA  1 -0.348 0.169  -0.034 
ATOM   1633  C  C   . ARG A 1 242 ? -37.846 18.389  -15.08  1    114.13 ? 231 ARG A C   1 -0.347 0.169  -0.038 
ATOM   1634  O  O   . ARG A 1 242 ? -38.746 17.967  -15.819 1    110.84 ? 231 ARG A O   1 -0.355 0.165  -0.039 
ATOM   1635  C  CB  . ARG A 1 242 ? -38.18  19.887  -13.068 1    100.36 ? 231 ARG A CB  1 -0.35  0.182  -0.033 
ATOM   1636  C  CG  . ARG A 1 242 ? -39.612 20.372  -12.893 1    103.69 ? 231 ARG A CG  1 -0.363 0.187  -0.032 
ATOM   1637  C  CD  . ARG A 1 242 ? -39.652 21.875  -12.564 1    105.94 ? 231 ARG A CD  1 -0.363 0.2    -0.031 
ATOM   1638  N  NE  . ARG A 1 242 ? -39.263 22.718  -13.692 1    109.11 ? 231 ARG A NE  1 -0.36  0.208  -0.034 
ATOM   1639  C  CZ  . ARG A 1 242 ? -38.031 23.164  -13.912 1    110.8  ? 231 ARG A CZ  1 -0.349 0.212  -0.035 
ATOM   1640  N  NH1 . ARG A 1 242 ? -37.027 22.858  -13.105 1    111.06 ? 231 ARG A NH1 1 -0.339 0.209  -0.033 
ATOM   1641  N  NH2 . ARG A 1 242 ? -37.801 23.934  -14.972 1    117.4  ? 231 ARG A NH2 1 -0.346 0.219  -0.037 
ATOM   1642  N  N   . HIS A 1 243 ? -36.664 18.775  -15.562 1    110.89 ? 232 HIS A N   1 -0.336 0.172  -0.039 
ATOM   1643  C  CA  . HIS A 1 243 ? -36.442 18.917  -16.993 1    108.52 ? 232 HIS A CA  1 -0.334 0.173  -0.042 
ATOM   1644  C  C   . HIS A 1 243 ? -36.45  17.57   -17.698 1    111.55 ? 232 HIS A C   1 -0.334 0.161  -0.044 
ATOM   1645  O  O   . HIS A 1 243 ? -37.292 17.313  -18.562 1    115.18 ? 232 HIS A O   1 -0.342 0.159  -0.046 
ATOM   1646  C  CB  . HIS A 1 243 ? -35.127 19.654  -17.241 1    106    ? 232 HIS A CB  1 -0.322 0.18   -0.043 
ATOM   1647  C  CG  . HIS A 1 243 ? -35.322 21.113  -17.489 1    117.57 ? 232 HIS A CG  1 -0.324 0.193  -0.044 
ATOM   1648  N  ND1 . HIS A 1 243 ? -35.109 22.07   -16.519 1    116.58 ? 232 HIS A ND1 1 -0.322 0.202  -0.041 
ATOM   1649  C  CD2 . HIS A 1 243 ? -35.766 21.777  -18.585 1    127.03 ? 232 HIS A CD2 1 -0.328 0.2    -0.046 
ATOM   1650  C  CE1 . HIS A 1 243 ? -35.391 23.264  -17.015 1    120.41 ? 232 HIS A CE1 1 -0.324 0.213  -0.042 
ATOM   1651  N  NE2 . HIS A 1 243 ? -35.793 23.114  -18.266 1    126.62 ? 232 HIS A NE2 1 -0.328 0.212  -0.046 
ATOM   1652  N  N   . SER A 1 244 ? -35.529 16.692  -17.335 1    109.65 ? 233 SER A N   1 -0.326 0.153  -0.043 
ATOM   1653  C  CA  . SER A 1 244 ? -35.238 15.543  -18.166 1    108.34 ? 233 SER A CA  1 -0.323 0.142  -0.045 
ATOM   1654  C  C   . SER A 1 244 ? -35.767 14.214  -17.637 1    111.4  ? 233 SER A C   1 -0.328 0.13   -0.044 
ATOM   1655  O  O   . SER A 1 244 ? -35.729 13.228  -18.377 1    120.18 ? 233 SER A O   1 -0.327 0.121  -0.046 
ATOM   1656  C  CB  . SER A 1 244 ? -33.722 15.442  -18.382 1    105.97 ? 233 SER A CB  1 -0.309 0.142  -0.046 
ATOM   1657  O  OG  . SER A 1 244 ? -33.244 16.605  -19.032 1    105.19 ? 233 SER A OG  1 -0.305 0.152  -0.048 
ATOM   1658  N  N   . PHE A 1 245 ? -36.27  14.143  -16.403 1    106.95 ? 234 PHE A N   1 -0.332 0.13   -0.041 
ATOM   1659  C  CA  . PHE A 1 245 ? -36.643 12.852  -15.833 1    102.57 ? 234 PHE A CA  1 -0.336 0.118  -0.04  
ATOM   1660  C  C   . PHE A 1 245 ? -38.069 12.809  -15.294 1    105.32 ? 234 PHE A C   1 -0.349 0.117  -0.038 
ATOM   1661  O  O   . PHE A 1 245 ? -38.452 11.803  -14.682 1    104.93 ? 234 PHE A O   1 -0.352 0.108  -0.037 
ATOM   1662  C  CB  . PHE A 1 245 ? -35.699 12.458  -14.697 1    103.5  ? 234 PHE A CB  1 -0.327 0.114  -0.037 
ATOM   1663  C  CG  . PHE A 1 245 ? -34.264 12.271  -15.096 1    101.85 ? 234 PHE A CG  1 -0.314 0.112  -0.038 
ATOM   1664  C  CD1 . PHE A 1 245 ? -33.518 13.313  -15.628 1    104.68 ? 234 PHE A CD1 1 -0.307 0.122  -0.039 
ATOM   1665  C  CD2 . PHE A 1 245 ? -33.633 11.071  -14.844 1    96.87  ? 234 PHE A CD2 1 -0.308 0.101  -0.037 
ATOM   1666  C  CE1 . PHE A 1 245 ? -32.182 13.147  -15.958 1    99.71  ? 234 PHE A CE1 1 -0.295 0.12   -0.04  
ATOM   1667  C  CE2 . PHE A 1 245 ? -32.297 10.897  -15.162 1    99.66  ? 234 PHE A CE2 1 -0.296 0.1    -0.038 
ATOM   1668  C  CZ  . PHE A 1 245 ? -31.571 11.936  -15.724 1    96.94  ? 234 PHE A CZ  1 -0.289 0.109  -0.039 
ATOM   1669  N  N   . SER A 1 246 ? -38.866 13.86   -15.496 1    104.99 ? 235 SER A N   1 -0.356 0.127  -0.039 
ATOM   1670  C  CA  . SER A 1 246 ? -40.185 13.969  -14.881 1    102.8  ? 235 SER A CA  1 -0.368 0.128  -0.037 
ATOM   1671  C  C   . SER A 1 246 ? -41.08  12.762  -15.136 1    105.69 ? 235 SER A C   1 -0.376 0.117  -0.038 
ATOM   1672  O  O   . SER A 1 246 ? -42.091 12.578  -14.454 1    104.48 ? 235 SER A O   1 -0.386 0.115  -0.036 
ATOM   1673  C  CB  . SER A 1 246 ? -40.882 15.238  -15.376 1    106.95 ? 235 SER A CB  1 -0.375 0.14   -0.038 
ATOM   1674  O  OG  . SER A 1 246 ? -40.293 15.689  -16.589 1    116.79 ? 235 SER A OG  1 -0.369 0.144  -0.041 
ATOM   1675  N  N   . HIS A 1 247 ? -40.707 11.932  -16.114 1    112.89 ? 236 HIS A N   1 -0.373 0.109  -0.04  
ATOM   1676  C  CA  . HIS A 1 247 ? -41.509 10.785  -16.524 1    113.35 ? 236 HIS A CA  1 -0.38  0.099  -0.041 
ATOM   1677  C  C   . HIS A 1 247 ? -41.206 9.55    -15.701 1    107.73 ? 236 HIS A C   1 -0.378 0.088  -0.039 
ATOM   1678  O  O   . HIS A 1 247 ? -42.091 8.704   -15.515 1    101.68 ? 236 HIS A O   1 -0.386 0.08   -0.039 
ATOM   1679  C  CB  . HIS A 1 247 ? -41.303 10.486  -18.019 1    116.75 ? 236 HIS A CB  1 -0.379 0.096  -0.045 
ATOM   1680  C  CG  . HIS A 1 247 ? -39.864 10.473  -18.472 1    124.29 ? 236 HIS A CG  1 -0.365 0.096  -0.046 
ATOM   1681  N  ND1 . HIS A 1 247 ? -38.987 11.515  -18.248 1    120.52 ? 236 HIS A ND1 1 -0.357 0.106  -0.046 
ATOM   1682  C  CD2 . HIS A 1 247 ? -39.171 9.558   -19.197 1    131.71 ? 236 HIS A CD2 1 -0.359 0.088  -0.048 
ATOM   1683  C  CE1 . HIS A 1 247 ? -37.815 11.232  -18.789 1    121.22 ? 236 HIS A CE1 1 -0.347 0.103  -0.047 
ATOM   1684  N  NE2 . HIS A 1 247 ? -37.899 10.051  -19.372 1    126.71 ? 236 HIS A NE2 1 -0.347 0.092  -0.048 
ATOM   1685  N  N   . LEU A 1 248 ? -39.979 9.441   -15.195 1    113.47 ? 237 LEU A N   1 -0.366 0.087  -0.038 
ATOM   1686  C  CA  . LEU A 1 248 ? -39.652 8.41    -14.22  1    110.81 ? 237 LEU A CA  1 -0.363 0.077  -0.036 
ATOM   1687  C  C   . LEU A 1 248 ? -40.403 8.651   -12.921 1    103.66 ? 237 LEU A C   1 -0.37  0.079  -0.032 
ATOM   1688  O  O   . LEU A 1 248 ? -40.889 9.75    -12.642 1    104.51 ? 237 LEU A O   1 -0.375 0.089  -0.032 
ATOM   1689  C  CB  . LEU A 1 248 ? -38.152 8.383   -13.922 1    106.42 ? 237 LEU A CB  1 -0.35  0.077  -0.035 
ATOM   1690  C  CG  . LEU A 1 248 ? -37.201 8.076   -15.08  1    111.7  ? 237 LEU A CG  1 -0.341 0.074  -0.038 
ATOM   1691  C  CD1 . LEU A 1 248 ? -36.837 9.344   -15.811 1    115.16 ? 237 LEU A CD1 1 -0.338 0.086  -0.039 
ATOM   1692  C  CD2 . LEU A 1 248 ? -35.944 7.368   -14.621 1    112.09 ? 237 LEU A CD2 1 -0.329 0.068  -0.037 
ATOM   1693  N  N   . SER A 1 249 ? -40.477 7.61    -12.104 1    108.21 ? 238 SER A N   1 -0.371 0.07   -0.03  
ATOM   1694  C  CA  . SER A 1 249 ? -41.136 7.705   -10.8   1    109.21 ? 238 SER A CA  1 -0.377 0.071  -0.027 
ATOM   1695  C  C   . SER A 1 249 ? -40.088 8.049   -9.749  1    99.7   ? 238 SER A C   1 -0.367 0.074  -0.024 
ATOM   1696  O  O   . SER A 1 249 ? -39.24  7.215   -9.419  1    94.75  ? 238 SER A O   1 -0.36  0.066  -0.024 
ATOM   1697  C  CB  . SER A 1 249 ? -41.855 6.408   -10.452 1    95.75  ? 238 SER A CB  1 -0.384 0.059  -0.026 
ATOM   1698  O  OG  . SER A 1 249 ? -42.981 6.705   -9.655  1    109.51 ? 238 SER A OG  1 -0.394 0.061  -0.024 
ATOM   1699  N  N   . ILE A 1 250 ? -40.116 9.285   -9.255  1    99.52  ? 239 ILE A N   1 -0.368 0.085  -0.023 
ATOM   1700  C  CA  . ILE A 1 250 ? -39.135 9.749   -8.278  1    108.99 ? 239 ILE A CA  1 -0.359 0.089  -0.021 
ATOM   1701  C  C   . ILE A 1 250 ? -39.85  10.422  -7.111  1    107.32 ? 239 ILE A C   1 -0.365 0.096  -0.018 
ATOM   1702  O  O   . ILE A 1 250 ? -40.577 11.405  -7.303  1    109.18 ? 239 ILE A O   1 -0.372 0.105  -0.018 
ATOM   1703  C  CB  . ILE A 1 250 ? -38.116 10.723  -8.888  1    108.03 ? 239 ILE A CB  1 -0.349 0.098  -0.022 
ATOM   1704  C  CG1 . ILE A 1 250 ? -37.61  10.224  -10.229 1    99.15  ? 239 ILE A CG1 1 -0.345 0.094  -0.026 
ATOM   1705  C  CG2 . ILE A 1 250 ? -36.942 10.951  -7.935  1    108.13 ? 239 ILE A CG2 1 -0.339 0.1    -0.02  
ATOM   1706  C  CD1 . ILE A 1 250 ? -38.191 11.054  -11.377 1    110.21 ? 239 ILE A CD1 1 -0.35  0.101  -0.028 
ATOM   1707  N  N   . CYS A 1 251 ? -39.61  9.925   -5.906  1    108.67 ? 240 CYS A N   1 -0.363 0.091  -0.015 
ATOM   1708  C  CA  . CYS A 1 251 ? -39.971 10.622  -4.686  1    107.91 ? 240 CYS A CA  1 -0.366 0.097  -0.012 
ATOM   1709  C  C   . CYS A 1 251 ? -38.693 11.269  -4.165  1    108.26 ? 240 CYS A C   1 -0.355 0.103  -0.01  
ATOM   1710  O  O   . CYS A 1 251 ? -37.718 10.573  -3.857  1    103.06 ? 240 CYS A O   1 -0.346 0.097  -0.01  
ATOM   1711  C  CB  . CYS A 1 251 ? -40.586 9.655   -3.67   1    108.42 ? 240 CYS A CB  1 -0.372 0.088  -0.009 
ATOM   1712  S  SG  . CYS A 1 251 ? -41.218 10.412  -2.122  1    139.42 ? 240 CYS A SG  1 -0.378 0.095  -0.005 
ATOM   1713  N  N   . HIS A 1 252 ? -38.672 12.597  -4.13   1    108.74 ? 241 HIS A N   1 -0.354 0.115  -0.01  
ATOM   1714  C  CA  . HIS A 1 252 ? -37.468 13.355  -3.791  1    106.01 ? 241 HIS A CA  1 -0.343 0.122  -0.009 
ATOM   1715  C  C   . HIS A 1 252 ? -37.741 14.219  -2.561  1    108.42 ? 241 HIS A C   1 -0.346 0.13   -0.006 
ATOM   1716  O  O   . HIS A 1 252 ? -38.338 15.296  -2.679  1    107.15 ? 241 HIS A O   1 -0.351 0.14   -0.007 
ATOM   1717  C  CB  . HIS A 1 252 ? -37.038 14.205  -4.975  1    105.67 ? 241 HIS A CB  1 -0.339 0.13   -0.012 
ATOM   1718  C  CG  . HIS A 1 252 ? -35.817 15.03   -4.721  1    104.71 ? 241 HIS A CG  1 -0.328 0.138  -0.012 
ATOM   1719  N  ND1 . HIS A 1 252 ? -35.511 16.15   -5.463  1    110.51 ? 241 HIS A ND1 1 -0.325 0.148  -0.014 
ATOM   1720  C  CD2 . HIS A 1 252 ? -34.818 14.892  -3.821  1    105.11 ? 241 HIS A CD2 1 -0.319 0.136  -0.01  
ATOM   1721  C  CE1 . HIS A 1 252 ? -34.382 16.675  -5.023  1    104.54 ? 241 HIS A CE1 1 -0.315 0.153  -0.013 
ATOM   1722  N  NE2 . HIS A 1 252 ? -33.941 15.931  -4.026  1    102.67 ? 241 HIS A NE2 1 -0.311 0.146  -0.01  
ATOM   1723  N  N   . ILE A 1 253 ? -37.299 13.752  -1.391  1    113.89 ? 242 ILE A N   1 -0.342 0.126  -0.003 
ATOM   1724  C  CA  . ILE A 1 253 ? -37.405 14.502  -0.136  1    110.12 ? 242 ILE A CA  1 -0.343 0.133  -0.0   
ATOM   1725  C  C   . ILE A 1 253 ? -36.13  15.318  0.04    1    103.25 ? 242 ILE A C   1 -0.331 0.14   0.0    
ATOM   1726  O  O   . ILE A 1 253 ? -35.042 14.759  0.227   1    96.55  ? 242 ILE A O   1 -0.321 0.135  0.001  
ATOM   1727  C  CB  . ILE A 1 253 ? -37.63  13.585  1.068   1    100.34 ? 242 ILE A CB  1 -0.345 0.124  0.003  
ATOM   1728  C  CG1 . ILE A 1 253 ? -39.02  12.96   1.026   1    104.21 ? 242 ILE A CG1 1 -0.358 0.119  0.003  
ATOM   1729  C  CG2 . ILE A 1 253 ? -37.507 14.378  2.329   1    110.01 ? 242 ILE A CG2 1 -0.344 0.132  0.006  
ATOM   1730  C  CD1 . ILE A 1 253 ? -39.03  11.571  0.467   1    109.01 ? 242 ILE A CD1 1 -0.358 0.106  0.001  
ATOM   1731  N  N   . ASP A 1 254 ? -36.269 16.641  -0.024  1    101.45 ? 243 ASP A N   1 -0.332 0.153  -0.0   
ATOM   1732  C  CA  . ASP A 1 254 ? -35.138 17.562  -0.048  1    101.24 ? 243 ASP A CA  1 -0.322 0.161  -0.0   
ATOM   1733  C  C   . ASP A 1 254 ? -35.182 18.373  1.237   1    103.86 ? 243 ASP A C   1 -0.322 0.168  0.003  
ATOM   1734  O  O   . ASP A 1 254 ? -36.072 19.212  1.423   1    101.35 ? 243 ASP A O   1 -0.331 0.176  0.004  
ATOM   1735  C  CB  . ASP A 1 254 ? -35.164 18.473  -1.274  1    101.27 ? 243 ASP A CB  1 -0.322 0.169  -0.003 
ATOM   1736  C  CG  . ASP A 1 254 ? -33.916 19.362  -1.373  1    102.25 ? 243 ASP A CG  1 -0.311 0.177  -0.003 
ATOM   1737  O  OD1 . ASP A 1 254 ? -32.983 19.157  -0.567  1    100.36 ? 243 ASP A OD1 1 -0.302 0.176  -0.001 
ATOM   1738  O  OD2 . ASP A 1 254 ? -33.859 20.264  -2.248  1    103.31 ? 243 ASP A OD2 1 -0.31  0.186  -0.006 
ATOM   1739  N  N   . VAL A 1 255 ? -34.207 18.121  2.101   1    101.78 ? 244 VAL A N   1 -0.313 0.166  0.005  
ATOM   1740  C  CA  . VAL A 1 255 ? -34.112 18.723  3.416   1    99.6   ? 244 VAL A CA  1 -0.313 0.172  0.009  
ATOM   1741  C  C   . VAL A 1 255 ? -33.125 19.878  3.327   1    100.48 ? 244 VAL A C   1 -0.304 0.182  0.008  
ATOM   1742  O  O   . VAL A 1 255 ? -31.97  19.673  2.932   1    103.44 ? 244 VAL A O   1 -0.293 0.18   0.007  
ATOM   1743  C  CB  . VAL A 1 255 ? -33.661 17.681  4.449   1    104.71 ? 244 VAL A CB  1 -0.308 0.162  0.011  
ATOM   1744  C  CG1 . VAL A 1 255 ? -33.273 18.346  5.787   1    103.88 ? 244 VAL A CG1 1 -0.305 0.168  0.014  
ATOM   1745  C  CG2 . VAL A 1 255 ? -34.739 16.592  4.608   1    96.19  ? 244 VAL A CG2 1 -0.318 0.152  0.012  
ATOM   1746  N  N   . PHE A 1 256 ? -33.564 21.089  3.684   1    97.52  ? 245 PHE A N   1 -0.308 0.193  0.009  
ATOM   1747  C  CA  . PHE A 1 256 ? -32.674 22.245  3.647   1    96.69  ? 245 PHE A CA  1 -0.299 0.204  0.009  
ATOM   1748  C  C   . PHE A 1 256 ? -33.244 23.386  4.482   1    99.46  ? 245 PHE A C   1 -0.305 0.214  0.011  
ATOM   1749  O  O   . PHE A 1 256 ? -34.396 23.361  4.924   1    99.09  ? 245 PHE A O   1 -0.315 0.214  0.012  
ATOM   1750  C  CB  . PHE A 1 256 ? -32.439 22.717  2.211   1    98.96  ? 245 PHE A CB  1 -0.297 0.208  0.006  
ATOM   1751  C  CG  . PHE A 1 256 ? -33.645 23.337  1.585   1    97.73  ? 245 PHE A CG  1 -0.308 0.214  0.004  
ATOM   1752  C  CD1 . PHE A 1 256 ? -34.594 22.545  0.942   1    96.9   ? 245 PHE A CD1 1 -0.317 0.207  0.002  
ATOM   1753  C  CD2 . PHE A 1 256 ? -33.832 24.713  1.633   1    93.75  ? 245 PHE A CD2 1 -0.31  0.226  0.004  
ATOM   1754  C  CE1 . PHE A 1 256 ? -35.707 23.113  0.367   1    92.55  ? 245 PHE A CE1 1 -0.327 0.212  0.001  
ATOM   1755  C  CE2 . PHE A 1 256 ? -34.946 25.29   1.055   1    96.83  ? 245 PHE A CE2 1 -0.32  0.232  0.003  
ATOM   1756  C  CZ  . PHE A 1 256 ? -35.884 24.49   0.423   1    97.57  ? 245 PHE A CZ  1 -0.329 0.224  0.001  
ATOM   1757  N  N   . ASP A 1 257 ? -32.415 24.41   4.666   1    95.62  ? 246 ASP A N   1 -0.297 0.224  0.012  
ATOM   1758  C  CA  . ASP A 1 257 ? -32.791 25.631  5.369   1    96.15  ? 246 ASP A CA  1 -0.301 0.235  0.013  
ATOM   1759  C  C   . ASP A 1 257 ? -32.863 26.772  4.356   1    98.83  ? 246 ASP A C   1 -0.301 0.245  0.011  
ATOM   1760  O  O   . ASP A 1 257 ? -31.824 27.259  3.887   1    96.53  ? 246 ASP A O   1 -0.292 0.25   0.01   
ATOM   1761  C  CB  . ASP A 1 257 ? -31.778 25.925  6.477   1    99.4   ? 246 ASP A CB  1 -0.291 0.238  0.016  
ATOM   1762  C  CG  . ASP A 1 257 ? -32.205 27.078  7.394   1    100.67 ? 246 ASP A CG  1 -0.295 0.248  0.018  
ATOM   1763  O  OD1 . ASP A 1 257 ? -33.193 27.782  7.072   1    97.07  ? 246 ASP A OD1 1 -0.304 0.255  0.018  
ATOM   1764  O  OD2 . ASP A 1 257 ? -31.547 27.273  8.447   1    108.14 ? 246 ASP A OD2 1 -0.289 0.25   0.021  
ATOM   1765  N  N   . SER A 1 258 ? -34.088 27.24   4.064   1    93.37  ? 247 SER A N   1 -0.312 0.25   0.01   
ATOM   1766  C  CA  . SER A 1 258 ? -34.304 28.379  3.161   1    93.27  ? 247 SER A CA  1 -0.314 0.26   0.008  
ATOM   1767  C  C   . SER A 1 258 ? -33.617 29.688  3.622   1    101.61 ? 247 SER A C   1 -0.308 0.272  0.009  
ATOM   1768  O  O   . SER A 1 258 ? -33.879 30.764  3.054   1    98.87  ? 247 SER A O   1 -0.31  0.282  0.008  
ATOM   1769  C  CB  . SER A 1 258 ? -35.803 28.631  2.983   1    95.67  ? 247 SER A CB  1 -0.328 0.262  0.007  
ATOM   1770  O  OG  . SER A 1 258 ? -36.346 29.387  4.043   1    91.43  ? 247 SER A OG  1 -0.333 0.269  0.01   
ATOM   1771  N  N   . ARG A 1 259 ? -32.754 29.649  4.635   1    105.8  ? 248 ARG A N   1 -0.3   0.272  0.012  
ATOM   1772  C  CA  . ARG A 1 259 ? -32.134 30.844  5.184   1    103.08 ? 248 ARG A CA  1 -0.294 0.283  0.013  
ATOM   1773  C  C   . ARG A 1 259 ? -30.661 30.971  4.846   1    105.17 ? 248 ARG A C   1 -0.281 0.284  0.012  
ATOM   1774  O  O   . ARG A 1 259 ? -30.134 32.087  4.878   1    113.8  ? 248 ARG A O   1 -0.276 0.294  0.012  
ATOM   1775  C  CB  . ARG A 1 259 ? -32.289 30.865  6.709   1    108.81 ? 248 ARG A CB  1 -0.296 0.283  0.017  
ATOM   1776  C  CG  . ARG A 1 259 ? -33.417 31.725  7.261   1    110.29 ? 248 ARG A CG  1 -0.306 0.291  0.018  
ATOM   1777  C  CD  . ARG A 1 259 ? -34.589 30.881  7.744   1    108.89 ? 248 ARG A CD  1 -0.317 0.283  0.019  
ATOM   1778  N  NE  . ARG A 1 259 ? -34.169 29.672  8.447   1    116.92 ? 248 ARG A NE  1 -0.313 0.272  0.021  
ATOM   1779  C  CZ  . ARG A 1 259 ? -33.767 29.641  9.711   1    111.37 ? 248 ARG A CZ  1 -0.309 0.272  0.024  
ATOM   1780  N  NH1 . ARG A 1 259 ? -33.609 30.749  10.408  1    110.62 ? 248 ARG A NH1 1 -0.308 0.282  0.026  
ATOM   1781  N  NH2 . ARG A 1 259 ? -33.517 28.466  10.286  1    106.54 ? 248 ARG A NH2 1 -0.307 0.261  0.026  
ATOM   1782  N  N   . VAL A 1 260 ? -29.978 29.863  4.563   1    101.95 ? 249 VAL A N   1 -0.275 0.274  0.011  
ATOM   1783  C  CA  . VAL A 1 260 ? -28.599 29.933  4.094   1    110.12 ? 249 VAL A CA  1 -0.262 0.274  0.01   
ATOM   1784  C  C   . VAL A 1 260 ? -28.598 29.834  2.586   1    109.26 ? 249 VAL A C   1 -0.262 0.273  0.006  
ATOM   1785  O  O   . VAL A 1 260 ? -29.619 30.078  1.937   1    112.18 ? 249 VAL A O   1 -0.271 0.276  0.005  
ATOM   1786  C  CB  . VAL A 1 260 ? -27.725 28.817  4.678   1    108.11 ? 249 VAL A CB  1 -0.254 0.264  0.012  
ATOM   1787  C  CG1 . VAL A 1 260 ? -27.363 29.141  6.111   1    115.17 ? 249 VAL A CG1 1 -0.251 0.267  0.015  
ATOM   1788  C  CG2 . VAL A 1 260 ? -28.437 27.467  4.533   1    97.3   ? 249 VAL A CG2 1 -0.261 0.252  0.011  
ATOM   1789  N  N   . TYR A 1 261 ? -27.464 29.435  2.031   1    112.16 ? 250 TYR A N   1 -0.252 0.27   0.005  
ATOM   1790  C  CA  . TYR A 1 261 ? -27.36  29.229  0.591   1    110.82 ? 250 TYR A CA  1 -0.251 0.268  0.001  
ATOM   1791  C  C   . TYR A 1 261 ? -28.333 28.139  0.138   1    105.38 ? 250 TYR A C   1 -0.26  0.258  0.0    
ATOM   1792  O  O   . TYR A 1 261 ? -28.392 27.066  0.757   1    102.72 ? 250 TYR A O   1 -0.26  0.248  0.002  
ATOM   1793  C  CB  . TYR A 1 261 ? -25.92  28.856  0.244   1    110.62 ? 250 TYR A CB  1 -0.238 0.264  0.001  
ATOM   1794  C  CG  . TYR A 1 261 ? -25.628 28.729  -1.219  1    114.32 ? 250 TYR A CG  1 -0.235 0.263  -0.003 
ATOM   1795  C  CD1 . TYR A 1 261 ? -25.81  27.517  -1.879  1    109.68 ? 250 TYR A CD1 1 -0.237 0.252  -0.005 
ATOM   1796  C  CD2 . TYR A 1 261 ? -25.153 29.813  -1.949  1    117.52 ? 250 TYR A CD2 1 -0.231 0.273  -0.005 
ATOM   1797  C  CE1 . TYR A 1 261 ? -25.542 27.39   -3.213  1    104.48 ? 250 TYR A CE1 1 -0.234 0.251  -0.008 
ATOM   1798  C  CE2 . TYR A 1 261 ? -24.882 29.69   -3.305  1    106.41 ? 250 TYR A CE2 1 -0.228 0.272  -0.008 
ATOM   1799  C  CZ  . TYR A 1 261 ? -25.075 28.475  -3.925  1    105.98 ? 250 TYR A CZ  1 -0.23  0.261  -0.01  
ATOM   1800  O  OH  . TYR A 1 261 ? -24.803 28.322  -5.274  1    120.38 ? 250 TYR A OH  1 -0.227 0.26   -0.013 
ATOM   1801  N  N   . PRO A 1 262 ? -29.106 28.367  -0.927  1    107.78 ? 251 PRO A N   1 -0.267 0.26   -0.002 
ATOM   1802  C  CA  . PRO A 1 262 ? -29.161 29.578  -1.735  1    106.13 ? 251 PRO A CA  1 -0.267 0.271  -0.004 
ATOM   1803  C  C   . PRO A 1 262 ? -30.474 30.337  -1.566  1    102.58 ? 251 PRO A C   1 -0.279 0.278  -0.004 
ATOM   1804  O  O   . PRO A 1 262 ? -31.131 30.663  -2.534  1    100.74 ? 251 PRO A O   1 -0.285 0.281  -0.006 
ATOM   1805  C  CB  . PRO A 1 262 ? -28.996 29.017  -3.147  1    101.65 ? 251 PRO A CB  1 -0.266 0.266  -0.008 
ATOM   1806  C  CG  . PRO A 1 262 ? -29.807 27.735  -3.091  1    97.68  ? 251 PRO A CG  1 -0.273 0.254  -0.008 
ATOM   1807  C  CD  . PRO A 1 262 ? -29.712 27.236  -1.655  1    108.62 ? 251 PRO A CD  1 -0.272 0.25   -0.004 
ATOM   1808  N  N   . GLN A 1 263 ? -30.908 30.592  -0.336  1    108.87 ? 252 GLN A N   1 -0.283 0.28   -0.001 
ATOM   1809  C  CA  . GLN A 1 263 ? -31.983 31.539  -0.028  1    103.43 ? 252 GLN A CA  1 -0.293 0.289  -0.0   
ATOM   1810  C  C   . GLN A 1 263 ? -33.299 31.23   -0.742  1    103.33 ? 252 GLN A C   1 -0.305 0.286  -0.002 
ATOM   1811  O  O   . GLN A 1 263 ? -34.188 32.089  -0.791  1    103.08 ? 252 GLN A O   1 -0.313 0.294  -0.002 
ATOM   1812  C  CB  . GLN A 1 263 ? -31.548 32.972  -0.354  1    105.02 ? 252 GLN A CB  1 -0.289 0.302  -0.001 
ATOM   1813  C  CG  . GLN A 1 263 ? -30.177 33.349  0.201   1    108.75 ? 252 GLN A CG  1 -0.277 0.306  0.001  
ATOM   1814  C  CD  . GLN A 1 263 ? -30.205 33.589  1.689   1    112.63 ? 252 GLN A CD  1 -0.277 0.308  0.004  
ATOM   1815  O  OE1 . GLN A 1 263 ? -31.273 33.79   2.265   1    120.09 ? 252 GLN A OE1 1 -0.287 0.31   0.006  
ATOM   1816  N  NE2 . GLN A 1 263 ? -29.034 33.558  2.33    1    112.45 ? 252 GLN A NE2 1 -0.266 0.308  0.006  
ATOM   1817  N  N   . GLN A 1 264 ? -33.476 30.033  -1.3    1    103.55 ? 253 GLN A N   1 -0.307 0.275  -0.003 
ATOM   1818  C  CA  . GLN A 1 264 ? -34.685 29.72   -2.051  1    105.88 ? 253 GLN A CA  1 -0.318 0.272  -0.005 
ATOM   1819  C  C   . GLN A 1 264 ? -35.7   29.022  -1.155  1    105.77 ? 253 GLN A C   1 -0.327 0.266  -0.003 
ATOM   1820  O  O   . GLN A 1 264 ? -35.376 28.03   -0.493  1    103.6  ? 253 GLN A O   1 -0.324 0.257  -0.001 
ATOM   1821  C  CB  . GLN A 1 264 ? -34.355 28.855  -3.271  1    104.25 ? 253 GLN A CB  1 -0.315 0.264  -0.008 
ATOM   1822  C  CG  . GLN A 1 264 ? -33.587 29.611  -4.34   1    104.18 ? 253 GLN A CG  1 -0.308 0.271  -0.011 
ATOM   1823  C  CD  . GLN A 1 264 ? -32.715 28.708  -5.188  1    105.89 ? 253 GLN A CD  1 -0.3   0.263  -0.013 
ATOM   1824  O  OE1 . GLN A 1 264 ? -32.844 27.48   -5.142  1    103.73 ? 253 GLN A OE1 1 -0.301 0.252  -0.013 
ATOM   1825  N  NE2 . GLN A 1 264 ? -31.808 29.311  -5.963  1    103.14 ? 253 GLN A NE2 1 -0.291 0.269  -0.015 
ATOM   1826  N  N   . ASP A 1 265 ? -36.922 29.55   -1.13   1    107.54 ? 254 ASP A N   1 -0.338 0.271  -0.003 
ATOM   1827  C  CA  . ASP A 1 265 ? -38.005 29.033  -0.301  1    106.02 ? 254 ASP A CA  1 -0.348 0.266  -0.001 
ATOM   1828  C  C   . ASP A 1 265 ? -39.159 28.551  -1.188  1    108.97 ? 254 ASP A C   1 -0.359 0.262  -0.003 
ATOM   1829  O  O   . ASP A 1 265 ? -39.005 28.372  -2.399  1    110.87 ? 254 ASP A O   1 -0.357 0.26   -0.006 
ATOM   1830  C  CB  . ASP A 1 265 ? -38.463 30.09   0.713   1    109.92 ? 254 ASP A CB  1 -0.352 0.276  0.002  
ATOM   1831  C  CG  . ASP A 1 265 ? -39.136 31.301  0.062   1    115.84 ? 254 ASP A CG  1 -0.359 0.287  0.0    
ATOM   1832  O  OD1 . ASP A 1 265 ? -38.441 32.08   -0.638  1    115.4  ? 254 ASP A OD1 1 -0.352 0.294  -0.002 
ATOM   1833  O  OD2 . ASP A 1 265 ? -40.366 31.477  0.274   1    116.67 ? 254 ASP A OD2 1 -0.37  0.288  0.001  
ATOM   1834  N  N   . PHE A 1 266 ? -40.326 28.341  -0.568  1    108.14 ? 255 PHE A N   1 -0.37  0.26   -0.001 
ATOM   1835  C  CA  . PHE A 1 266 ? -41.465 27.774  -1.285  1    108.97 ? 255 PHE A CA  1 -0.38  0.255  -0.003 
ATOM   1836  C  C   . PHE A 1 266 ? -41.951 28.699  -2.396  1    107.39 ? 255 PHE A C   1 -0.384 0.263  -0.006 
ATOM   1837  O  O   . PHE A 1 266 ? -42.353 28.23   -3.467  1    110.23 ? 255 PHE A O   1 -0.388 0.259  -0.009 
ATOM   1838  C  CB  . PHE A 1 266 ? -42.607 27.468  -0.318  1    112.63 ? 255 PHE A CB  1 -0.39  0.252  -0.001 
ATOM   1839  C  CG  . PHE A 1 266 ? -42.226 26.556  0.809   1    117.77 ? 255 PHE A CG  1 -0.387 0.243  0.002  
ATOM   1840  C  CD1 . PHE A 1 266 ? -41.944 25.221  0.58    1    115.04 ? 255 PHE A CD1 1 -0.384 0.231  0.001  
ATOM   1841  C  CD2 . PHE A 1 266 ? -42.172 27.032  2.105   1    120.82 ? 255 PHE A CD2 1 -0.386 0.248  0.005  
ATOM   1842  C  CE1 . PHE A 1 266 ? -41.603 24.387  1.621   1    117.75 ? 255 PHE A CE1 1 -0.381 0.223  0.004  
ATOM   1843  C  CE2 . PHE A 1 266 ? -41.834 26.204  3.136   1    116.08 ? 255 PHE A CE2 1 -0.383 0.24   0.008  
ATOM   1844  C  CZ  . PHE A 1 266 ? -41.553 24.877  2.895   1    113.75 ? 255 PHE A CZ  1 -0.381 0.228  0.007  
ATOM   1845  N  N   . ALA A 1 267 ? -41.942 30.012  -2.159  1    103.99 ? 256 ALA A N   1 -0.384 0.275  -0.005 
ATOM   1846  C  CA  . ALA A 1 267 ? -42.31  30.94   -3.224  1    104.43 ? 256 ALA A CA  1 -0.388 0.284  -0.008 
ATOM   1847  C  C   . ALA A 1 267 ? -41.389 30.778  -4.425  1    112.02 ? 256 ALA A C   1 -0.379 0.282  -0.011 
ATOM   1848  O  O   . ALA A 1 267 ? -41.841 30.837  -5.575  1    114.46 ? 256 ALA A O   1 -0.383 0.283  -0.014 
ATOM   1849  C  CB  . ALA A 1 267 ? -42.276 32.38   -2.722  1    99.61  ? 256 ALA A CB  1 -0.387 0.297  -0.007 
ATOM   1850  N  N   . TYR A 1 268 ? -40.094 30.553  -4.174  1    110.53 ? 257 TYR A N   1 -0.367 0.28   -0.01  
ATOM   1851  C  CA  . TYR A 1 268 ? -39.143 30.369  -5.268  1    108.35 ? 257 TYR A CA  1 -0.359 0.278  -0.013 
ATOM   1852  C  C   . TYR A 1 268 ? -39.419 29.082  -6.032  1    105.58 ? 257 TYR A C   1 -0.361 0.267  -0.015 
ATOM   1853  O  O   . TYR A 1 268 ? -39.281 29.047  -7.255  1    109.02 ? 257 TYR A O   1 -0.36  0.266  -0.018 
ATOM   1854  C  CB  . TYR A 1 268 ? -37.72  30.371  -4.718  1    108.85 ? 257 TYR A CB  1 -0.346 0.278  -0.012 
ATOM   1855  C  CG  . TYR A 1 268 ? -36.624 30.456  -5.752  1    105.97 ? 257 TYR A CG  1 -0.336 0.279  -0.014 
ATOM   1856  C  CD1 . TYR A 1 268 ? -36.258 29.345  -6.5    1    106.1  ? 257 TYR A CD1 1 -0.332 0.269  -0.016 
ATOM   1857  C  CD2 . TYR A 1 268 ? -35.925 31.644  -5.95   1    106.8  ? 257 TYR A CD2 1 -0.329 0.29   -0.015 
ATOM   1858  C  CE1 . TYR A 1 268 ? -35.238 29.417  -7.434  1    107.6  ? 257 TYR A CE1 1 -0.323 0.27   -0.019 
ATOM   1859  C  CE2 . TYR A 1 268 ? -34.898 31.73   -6.885  1    106.47 ? 257 TYR A CE2 1 -0.32  0.291  -0.017 
ATOM   1860  C  CZ  . TYR A 1 268 ? -34.559 30.612  -7.617  1    107.02 ? 257 TYR A CZ  1 -0.317 0.281  -0.019 
ATOM   1861  O  OH  . TYR A 1 268 ? -33.542 30.679  -8.539  1    109.12 ? 257 TYR A OH  1 -0.307 0.281  -0.021 
ATOM   1862  N  N   . ILE A 1 269 ? -39.797 28.013  -5.33   1    107.84 ? 258 ILE A N   1 -0.365 0.257  -0.013 
ATOM   1863  C  CA  . ILE A 1 269 ? -40.155 26.769  -6.008  1    104.54 ? 258 ILE A CA  1 -0.368 0.245  -0.015 
ATOM   1864  C  C   . ILE A 1 269 ? -41.41  26.958  -6.836  1    105.86 ? 258 ILE A C   1 -0.379 0.247  -0.017 
ATOM   1865  O  O   . ILE A 1 269 ? -41.543 26.378  -7.917  1    116.27 ? 258 ILE A O   1 -0.381 0.242  -0.02  
ATOM   1866  C  CB  . ILE A 1 269 ? -40.356 25.613  -5.011  1    114.87 ? 258 ILE A CB  1 -0.37  0.235  -0.013 
ATOM   1867  C  CG1 . ILE A 1 269 ? -39.294 25.614  -3.904  1    110.8  ? 258 ILE A CG1 1 -0.36  0.235  -0.01  
ATOM   1868  C  CG2 . ILE A 1 269 ? -40.44  24.269  -5.777  1    107.92 ? 258 ILE A CG2 1 -0.371 0.222  -0.014 
ATOM   1869  C  CD1 . ILE A 1 269 ? -37.934 25.159  -4.348  1    109.65 ? 258 ILE A CD1 1 -0.348 0.231  -0.011 
ATOM   1870  N  N   . ASN A 1 270 ? -42.381 27.712  -6.315  1    103.94 ? 259 ASN A N   1 -0.388 0.254  -0.016 
ATOM   1871  C  CA  . ASN A 1 270 ? -43.597 27.964  -7.081  1    107.21 ? 259 ASN A CA  1 -0.4   0.256  -0.018 
ATOM   1872  C  C   . ASN A 1 270 ? -43.265 28.515  -8.464  1    108.3  ? 259 ASN A C   1 -0.396 0.261  -0.021 
ATOM   1873  O  O   . ASN A 1 270 ? -43.723 27.989  -9.482  1    103.8  ? 259 ASN A O   1 -0.401 0.256  -0.024 
ATOM   1874  C  CB  . ASN A 1 270 ? -44.504 28.925  -6.32   1    110.41 ? 259 ASN A CB  1 -0.408 0.265  -0.016 
ATOM   1875  C  CG  . ASN A 1 270 ? -45.14  28.288  -5.113  1    105.52 ? 259 ASN A CG  1 -0.414 0.259  -0.013 
ATOM   1876  O  OD1 . ASN A 1 270 ? -45.056 27.073  -4.913  1    99.86  ? 259 ASN A OD1 1 -0.413 0.248  -0.012 
ATOM   1877  N  ND2 . ASN A 1 270 ? -45.802 29.106  -4.304  1    104.67 ? 259 ASN A ND2 1 -0.42  0.267  -0.011 
ATOM   1878  N  N   . ASN A 1 271 ? -42.441 29.564  -8.517  1    105.86 ? 260 ASN A N   1 -0.389 0.271  -0.021 
ATOM   1879  C  CA  . ASN A 1 271 ? -42.003 30.084  -9.802  1    104.67 ? 260 ASN A CA  1 -0.385 0.276  -0.024 
ATOM   1880  C  C   . ASN A 1 271 ? -41.225 29.042  -10.606 1    109.29 ? 260 ASN A C   1 -0.378 0.266  -0.026 
ATOM   1881  O  O   . ASN A 1 271 ? -41.228 29.089  -11.844 1    119.17 ? 260 ASN A O   1 -0.378 0.267  -0.03  
ATOM   1882  C  CB  . ASN A 1 271 ? -41.156 31.335  -9.597  1    103.69 ? 260 ASN A CB  1 -0.377 0.287  -0.024 
ATOM   1883  C  CG  . ASN A 1 271 ? -41.138 32.237  -10.828 1    117.65 ? 260 ASN A CG  1 -0.377 0.295  -0.027 
ATOM   1884  O  OD1 . ASN A 1 271 ? -40.695 31.846  -11.931 1    117.06 ? 260 ASN A OD1 1 -0.373 0.292  -0.03  
ATOM   1885  N  ND2 . ASN A 1 271 ? -41.63  33.457  -10.649 1    113.75 ? 260 ASN A ND2 1 -0.382 0.307  -0.027 
ATOM   1886  N  N   . GLU A 1 272 ? -40.564 28.096  -9.938  1    103.13 ? 261 GLU A N   1 -0.372 0.257  -0.025 
ATOM   1887  C  CA  . GLU A 1 272 ? -39.793 27.077  -10.647 1    102.19 ? 261 GLU A CA  1 -0.365 0.248  -0.027 
ATOM   1888  C  C   . GLU A 1 272 ? -40.699 26.063  -11.34  1    107.55 ? 261 GLU A C   1 -0.373 0.239  -0.028 
ATOM   1889  O  O   . GLU A 1 272 ? -40.505 25.743  -12.519 1    111.47 ? 261 GLU A O   1 -0.371 0.236  -0.031 
ATOM   1890  C  CB  . GLU A 1 272 ? -38.855 26.361  -9.683  1    102.24 ? 261 GLU A CB  1 -0.356 0.242  -0.024 
ATOM   1891  C  CG  . GLU A 1 272 ? -37.441 26.866  -9.675  1    105.32 ? 261 GLU A CG  1 -0.343 0.246  -0.024 
ATOM   1892  C  CD  . GLU A 1 272 ? -36.503 25.865  -9.017  1    109.13 ? 261 GLU A CD  1 -0.335 0.237  -0.023 
ATOM   1893  O  OE1 . GLU A 1 272 ? -36.961 24.728  -8.752  1    107.76 ? 261 GLU A OE1 1 -0.339 0.227  -0.022 
ATOM   1894  O  OE2 . GLU A 1 272 ? -35.321 26.203  -8.763  1    109.95 ? 261 GLU A OE2 1 -0.324 0.24   -0.022 
ATOM   1895  N  N   . PHE A 1 273 ? -41.667 25.511  -10.616 1    108.46 ? 262 PHE A N   1 -0.382 0.234  -0.027 
ATOM   1896  C  CA  . PHE A 1 273 ? -42.572 24.521  -11.185 1    112.35 ? 262 PHE A CA  1 -0.39  0.225  -0.028 
ATOM   1897  C  C   . PHE A 1 273 ? -43.777 25.161  -11.863 1    108.55 ? 262 PHE A C   1 -0.401 0.231  -0.03  
ATOM   1898  O  O   . PHE A 1 273 ? -44.68  24.442  -12.31  1    101.32 ? 262 PHE A O   1 -0.409 0.224  -0.031 
ATOM   1899  C  CB  . PHE A 1 273 ? -43.05  23.557  -10.093 1    109.83 ? 262 PHE A CB  1 -0.395 0.216  -0.025 
ATOM   1900  C  CG  . PHE A 1 273 ? -42.054 22.479  -9.733  1    107.93 ? 262 PHE A CG  1 -0.385 0.206  -0.024 
ATOM   1901  C  CD1 . PHE A 1 273 ? -40.9   22.782  -9.016  1    107.78 ? 262 PHE A CD1 1 -0.375 0.209  -0.023 
ATOM   1902  C  CD2 . PHE A 1 273 ? -42.297 21.148  -10.08  1    109.35 ? 262 PHE A CD2 1 -0.388 0.194  -0.025 
ATOM   1903  C  CE1 . PHE A 1 273 ? -39.99  21.78   -8.662  1    108.58 ? 262 PHE A CE1 1 -0.366 0.2    -0.022 
ATOM   1904  C  CE2 . PHE A 1 273 ? -41.394 20.135  -9.739  1    103.75 ? 262 PHE A CE2 1 -0.379 0.185  -0.024 
ATOM   1905  C  CZ  . PHE A 1 273 ? -40.238 20.455  -9.03   1    108.77 ? 262 PHE A CZ  1 -0.369 0.187  -0.023 
ATOM   1906  N  N   . ASN A 1 274 ? -43.783 26.492  -11.963 1    110.86 ? 263 ASN A N   1 -0.401 0.243  -0.03  
ATOM   1907  C  CA  . ASN A 1 274 ? -44.956 27.335  -12.194 1    112.5  ? 263 ASN A CA  1 -0.412 0.251  -0.03  
ATOM   1908  C  C   . ASN A 1 274 ? -46.25  26.626  -11.798 1    109.78 ? 263 ASN A C   1 -0.424 0.244  -0.029 
ATOM   1909  O  O   . ASN A 1 274 ? -47.22  26.585  -12.567 1    110.65 ? 263 ASN A O   1 -0.433 0.244  -0.031 
ATOM   1910  C  CB  . ASN A 1 274 ? -44.951 27.853  -13.636 1    100.93 ? 263 ASN A CB  1 -0.412 0.255  -0.034 
ATOM   1911  C  CG  . ASN A 1 274 ? -43.809 28.867  -13.875 1    105.81 ? 263 ASN A CG  1 -0.401 0.265  -0.035 
ATOM   1912  O  OD1 . ASN A 1 274 ? -43.949 30.067  -13.602 1    102.88 ? 263 ASN A OD1 1 -0.403 0.276  -0.034 
ATOM   1913  N  ND2 . ASN A 1 274 ? -42.665 28.371  -14.351 1    104.65 ? 263 ASN A ND2 1 -0.391 0.26   -0.036 
ATOM   1914  N  N   . SER A 1 275 ? -46.235 26.071  -10.576 1    106.94 ? 264 SER A N   1 -0.424 0.239  -0.026 
ATOM   1915  C  CA  . SER A 1 275 ? -47.393 25.535  -9.863  1    113.81 ? 264 SER A CA  1 -0.434 0.234  -0.025 
ATOM   1916  C  C   . SER A 1 275 ? -47.276 25.93   -8.392  1    110.34 ? 264 SER A C   1 -0.433 0.238  -0.021 
ATOM   1917  O  O   . SER A 1 275 ? -46.303 26.567  -7.97   1    107.37 ? 264 SER A O   1 -0.424 0.243  -0.02  
ATOM   1918  C  CB  . SER A 1 275 ? -47.492 24.011  -10.003 1    113.55 ? 264 SER A CB  1 -0.435 0.22   -0.025 
ATOM   1919  O  OG  . SER A 1 275 ? -46.881 23.361  -8.898  1    109.78 ? 264 SER A OG  1 -0.43  0.214  -0.022 
ATOM   1920  N  N   . GLU A 1 276 ? -48.264 25.541  -7.59   1    110.82 ? 265 GLU A N   1 -0.442 0.234  -0.019 
ATOM   1921  C  CA  . GLU A 1 276 ? -48.273 25.892  -6.169  1    112.56 ? 265 GLU A CA  1 -0.442 0.237  -0.015 
ATOM   1922  C  C   . GLU A 1 276 ? -48.229 24.62   -5.324  1    111.59 ? 265 GLU A C   1 -0.442 0.226  -0.013 
ATOM   1923  O  O   . GLU A 1 276 ? -49.211 23.869  -5.26   1    109.16 ? 265 GLU A O   1 -0.451 0.219  -0.013 
ATOM   1924  C  CB  . GLU A 1 276 ? -49.489 26.75   -5.827  1    111.23 ? 265 GLU A CB  1 -0.454 0.245  -0.015 
ATOM   1925  C  CG  . GLU A 1 276 ? -49.093 28.079  -5.187  1    123.12 ? 265 GLU A CG  1 -0.45  0.257  -0.013 
ATOM   1926  C  CD  . GLU A 1 276 ? -50.27  28.847  -4.589  1    138.07 ? 265 GLU A CD  1 -0.461 0.264  -0.011 
ATOM   1927  O  OE1 . GLU A 1 276 ? -51.143 29.297  -5.377  1    136.99 ? 265 GLU A OE1 1 -0.469 0.268  -0.013 
ATOM   1928  O  OE2 . GLU A 1 276 ? -50.308 29.001  -3.333  1    129.5  ? 265 GLU A OE2 1 -0.461 0.266  -0.008 
ATOM   1929  N  N   . GLY A 1 277 ? -47.097 24.398  -4.661  1    106.77 ? 266 GLY A N   1 -0.432 0.224  -0.012 
ATOM   1930  C  CA  . GLY A 1 277 ? -46.898 23.182  -3.894  1    117.3  ? 266 GLY A CA  1 -0.43  0.212  -0.01  
ATOM   1931  C  C   . GLY A 1 277 ? -47.746 23.132  -2.629  1    122.06 ? 266 GLY A C   1 -0.438 0.212  -0.007 
ATOM   1932  O  O   . GLY A 1 277 ? -47.563 23.956  -1.714  1    113.5  ? 266 GLY A O   1 -0.436 0.22   -0.004 
ATOM   1933  N  N   . VAL A 1 278 ? -48.636 22.139  -2.546  1    122.93 ? 267 VAL A N   1 -0.446 0.203  -0.006 
ATOM   1934  C  CA  . VAL A 1 278 ? -49.592 22.018  -1.45   1    118.03 ? 267 VAL A CA  1 -0.454 0.202  -0.004 
ATOM   1935  C  C   . VAL A 1 278 ? -48.881 21.661  -0.145  1    125.77 ? 267 VAL A C   1 -0.448 0.199  -0.0   
ATOM   1936  O  O   . VAL A 1 278 ? -47.902 20.9    -0.14   1    125.64 ? 267 VAL A O   1 -0.439 0.192  -0.0   
ATOM   1937  C  CB  . VAL A 1 278 ? -50.651 20.964  -1.812  1    111.45 ? 267 VAL A CB  1 -0.464 0.192  -0.005 
ATOM   1938  C  CG1 . VAL A 1 278 ? -51.463 21.441  -2.987  1    123.43 ? 267 VAL A CG1 1 -0.472 0.196  -0.007 
ATOM   1939  C  CG2 . VAL A 1 278 ? -49.986 19.628  -2.151  1    105.34 ? 267 VAL A CG2 1 -0.458 0.18   -0.005 
ATOM   1940  N  N   . ASP A 1 279 ? -49.384 22.207  0.976   1    125.65 ? 268 ASP A N   1 -0.453 0.204  0.002  
ATOM   1941  C  CA  . ASP A 1 279 ? -48.832 21.924  2.301   1    124.65 ? 268 ASP A CA  1 -0.448 0.201  0.006  
ATOM   1942  C  C   . ASP A 1 279 ? -49.275 20.535  2.763   1    123.58 ? 268 ASP A C   1 -0.452 0.188  0.007  
ATOM   1943  O  O   . ASP A 1 279 ? -50.474 20.272  2.891   1    123.11 ? 268 ASP A O   1 -0.463 0.186  0.007  
ATOM   1944  C  CB  . ASP A 1 279 ? -49.286 23.003  3.291   1    128.06 ? 268 ASP A CB  1 -0.452 0.211  0.008  
ATOM   1945  C  CG  . ASP A 1 279 ? -48.636 22.867  4.685   1    137.03 ? 268 ASP A CG  1 -0.446 0.21   0.012  
ATOM   1946  O  OD1 . ASP A 1 279 ? -48.362 21.729  5.124   1    137.04 ? 268 ASP A OD1 1 -0.443 0.199  0.013  
ATOM   1947  O  OD2 . ASP A 1 279 ? -48.405 23.905  5.359   1    138.47 ? 268 ASP A OD2 1 -0.444 0.219  0.013  
ATOM   1948  N  N   . ILE A 1 280 ? -48.309 19.645  3.018   1    123.78 ? 269 ILE A N   1 -0.443 0.18   0.008  
ATOM   1949  C  CA  . ILE A 1 280 ? -48.614 18.273  3.425   1    127.84 ? 269 ILE A CA  1 -0.446 0.167  0.009  
ATOM   1950  C  C   . ILE A 1 280 ? -48.497 18.057  4.929   1    132.36 ? 269 ILE A C   1 -0.444 0.165  0.012  
ATOM   1951  O  O   . ILE A 1 280 ? -49.029 17.059  5.441   1    134.92 ? 269 ILE A O   1 -0.449 0.156  0.014  
ATOM   1952  C  CB  . ILE A 1 280 ? -47.711 17.254  2.696   1    130.46 ? 269 ILE A CB  1 -0.437 0.158  0.007  
ATOM   1953  C  CG1 . ILE A 1 280 ? -46.256 17.346  3.194   1    124.67 ? 269 ILE A CG1 1 -0.424 0.159  0.008  
ATOM   1954  C  CG2 . ILE A 1 280 ? -47.841 17.398  1.183   1    117.54 ? 269 ILE A CG2 1 -0.438 0.159  0.003  
ATOM   1955  C  CD1 . ILE A 1 280 ? -45.88  16.21   4.116   1    123.88 ? 269 ILE A CD1 1 -0.42  0.149  0.01   
ATOM   1956  N  N   . GLY A 1 281 ? -47.816 18.946  5.645   1    131.52 ? 270 GLY A N   1 -0.438 0.174  0.014  
ATOM   1957  C  CA  . GLY A 1 281 ? -47.597 18.762  7.058   1    120.36 ? 270 GLY A CA  1 -0.436 0.172  0.018  
ATOM   1958  C  C   . GLY A 1 281 ? -46.86  19.935  7.657   1    127.24 ? 270 GLY A C   1 -0.429 0.183  0.019  
ATOM   1959  O  O   . GLY A 1 281 ? -47.246 21.095  7.451   1    125.15 ? 270 GLY A O   1 -0.433 0.193  0.019  
ATOM   1960  N  N   . LYS A 1 282 ? -45.773 19.635  8.375   1    132.55 ? 271 LYS A N   1 -0.419 0.18   0.021  
ATOM   1961  C  CA  . LYS A 1 282 ? -45.074 20.572  9.254   1    129.21 ? 271 LYS A CA  1 -0.413 0.189  0.023  
ATOM   1962  C  C   . LYS A 1 282 ? -44.461 21.745  8.493   1    125.67 ? 271 LYS A C   1 -0.407 0.199  0.021  
ATOM   1963  O  O   . LYS A 1 282 ? -43.241 21.961  8.534   1    119.41 ? 271 LYS A O   1 -0.396 0.201  0.021  
ATOM   1964  C  CB  . LYS A 1 282 ? -44.001 19.828  10.051  1    123.58 ? 271 LYS A CB  1 -0.403 0.182  0.025  
ATOM   1965  C  CG  . LYS A 1 282 ? -44.558 18.968  11.181  1    122.11 ? 271 LYS A CG  1 -0.408 0.174  0.028  
ATOM   1966  C  CD  . LYS A 1 282 ? -44.973 17.588  10.72   1    119.45 ? 271 LYS A CD  1 -0.412 0.161  0.027  
ATOM   1967  C  CE  . LYS A 1 282 ? -45.393 16.732  11.904  1    131.16 ? 271 LYS A CE  1 -0.416 0.153  0.03   
ATOM   1968  N  NZ  . LYS A 1 282 ? -45.759 15.341  11.511  1    130.62 ? 271 LYS A NZ  1 -0.419 0.141  0.029  
ATOM   1969  N  N   . ASN A 1 283 ? -45.331 22.535  7.856   1    128.35 ? 272 ASN A N   1 -0.415 0.207  0.02   
ATOM   1970  C  CA  . ASN A 1 283 ? -44.953 23.517  6.849   1    129.67 ? 272 ASN A CA  1 -0.412 0.216  0.017  
ATOM   1971  C  C   . ASN A 1 283 ? -43.887 22.906  5.949   1    131.32 ? 272 ASN A C   1 -0.402 0.21   0.015  
ATOM   1972  O  O   . ASN A 1 283 ? -42.7   23.262  6.007   1    125.92 ? 272 ASN A O   1 -0.391 0.213  0.015  
ATOM   1973  C  CB  . ASN A 1 283 ? -44.5   24.817  7.499   1    126.24 ? 272 ASN A CB  1 -0.408 0.227  0.019  
ATOM   1974  C  CG  . ASN A 1 283 ? -45.438 25.256  8.601   1    133.25 ? 272 ASN A CG  1 -0.416 0.231  0.021  
ATOM   1975  O  OD1 . ASN A 1 283 ? -45.002 25.729  9.655   1    131.4  ? 272 ASN A OD1 1 -0.412 0.236  0.024  
ATOM   1976  N  ND2 . ASN A 1 283 ? -46.741 25.067  8.38    1    134.44 ? 272 ASN A ND2 1 -0.428 0.23   0.021  
ATOM   1977  N  N   . ILE A 1 284 ? -44.32  21.92   5.171   1    127.09 ? 273 ILE A N   1 -0.406 0.201  0.013  
ATOM   1978  C  CA  . ILE A 1 284 ? -43.533 21.316  4.113   1    122.32 ? 273 ILE A CA  1 -0.399 0.195  0.01   
ATOM   1979  C  C   . ILE A 1 284 ? -44.463 21.075  2.939   1    123.18 ? 273 ILE A C   1 -0.407 0.193  0.007  
ATOM   1980  O  O   . ILE A 1 284 ? -45.488 20.399  3.085   1    120.68 ? 273 ILE A O   1 -0.417 0.187  0.008  
ATOM   1981  C  CB  . ILE A 1 284 ? -42.872 19.987  4.526   1    122.02 ? 273 ILE A CB  1 -0.393 0.183  0.011  
ATOM   1982  C  CG1 . ILE A 1 284 ? -42.423 19.257  3.251   1    121.04 ? 273 ILE A CG1 1 -0.389 0.176  0.008  
ATOM   1983  C  CG2 . ILE A 1 284 ? -43.824 19.126  5.355   1    121.22 ? 273 ILE A CG2 1 -0.402 0.175  0.013  
ATOM   1984  C  CD1 . ILE A 1 284 ? -41.66  17.993  3.481   1    119.08 ? 273 ILE A CD1 1 -0.382 0.165  0.009  
ATOM   1985  N  N   . HIS A 1 285 ? -44.094 21.598  1.777   1    123.3  ? 274 HIS A N   1 -0.404 0.198  0.004  
ATOM   1986  C  CA  . HIS A 1 285 ? -44.924 21.526  0.589   1    119.81 ? 274 HIS A CA  1 -0.412 0.197  0.001  
ATOM   1987  C  C   . HIS A 1 285 ? -44.398 20.451  -0.355  1    115.64 ? 274 HIS A C   1 -0.407 0.187  -0.001 
ATOM   1988  O  O   . HIS A 1 285 ? -43.22  20.079  -0.322  1    110.12 ? 274 HIS A O   1 -0.396 0.184  -0.001 
ATOM   1989  C  CB  . HIS A 1 285 ? -44.982 22.891  -0.111  1    119.41 ? 274 HIS A CB  1 -0.412 0.21   -0.0   
ATOM   1990  C  CG  . HIS A 1 285 ? -45.515 23.992  0.764   1    130.02 ? 274 HIS A CG  1 -0.417 0.22   0.002  
ATOM   1991  N  ND1 . HIS A 1 285 ? -45.693 23.846  2.128   1    126.94 ? 274 HIS A ND1 1 -0.419 0.219  0.005  
ATOM   1992  C  CD2 . HIS A 1 285 ? -45.908 25.255  0.469   1    132.34 ? 274 HIS A CD2 1 -0.421 0.231  0.001  
ATOM   1993  C  CE1 . HIS A 1 285 ? -46.169 24.968  2.633   1    125.24 ? 274 HIS A CE1 1 -0.423 0.229  0.007  
ATOM   1994  N  NE2 . HIS A 1 285 ? -46.31  25.84   1.649   1    132.03 ? 274 HIS A NE2 1 -0.424 0.237  0.004  
ATOM   1995  N  N   . VAL A 1 286 ? -45.299 19.927  -1.183  1    114.69 ? 275 VAL A N   1 -0.415 0.183  -0.003 
ATOM   1996  C  CA  . VAL A 1 286 ? -44.927 18.981  -2.225  1    117.35 ? 275 VAL A CA  1 -0.412 0.174  -0.006 
ATOM   1997  C  C   . VAL A 1 286 ? -45.367 19.543  -3.571  1    112.23 ? 275 VAL A C   1 -0.416 0.179  -0.009 
ATOM   1998  O  O   . VAL A 1 286 ? -46.433 20.157  -3.683  1    114.25 ? 275 VAL A O   1 -0.426 0.185  -0.009 
ATOM   1999  C  CB  . VAL A 1 286 ? -45.521 17.575  -1.976  1    113.81 ? 275 VAL A CB  1 -0.417 0.161  -0.005 
ATOM   2000  C  CG1 . VAL A 1 286 ? -47.005 17.51   -2.352  1    114.89 ? 275 VAL A CG1 1 -0.431 0.16   -0.006 
ATOM   2001  C  CG2 . VAL A 1 286 ? -44.715 16.515  -2.73   1    110.95 ? 275 VAL A CG2 1 -0.41  0.151  -0.007 
ATOM   2002  N  N   . TRP A 1 287 ? -44.524 19.368  -4.58   1    112.47 ? 276 TRP A N   1 -0.408 0.177  -0.011 
ATOM   2003  C  CA  . TRP A 1 287 ? -44.88  19.675  -5.961  1    115.39 ? 276 TRP A CA  1 -0.411 0.18   -0.015 
ATOM   2004  C  C   . TRP A 1 287 ? -44.898 18.379  -6.754  1    113.25 ? 276 TRP A C   1 -0.411 0.168  -0.017 
ATOM   2005  O  O   . TRP A 1 287 ? -44.091 17.476  -6.501  1    110.45 ? 276 TRP A O   1 -0.404 0.16   -0.016 
ATOM   2006  C  CB  . TRP A 1 287 ? -43.905 20.685  -6.617  1    106.59 ? 276 TRP A CB  1 -0.402 0.19   -0.017 
ATOM   2007  C  CG  . TRP A 1 287 ? -43.886 22.05   -5.947  1    115    ? 276 TRP A CG  1 -0.402 0.202  -0.015 
ATOM   2008  C  CD1 . TRP A 1 287 ? -44.46  23.207  -6.405  1    113.97 ? 276 TRP A CD1 1 -0.407 0.213  -0.016 
ATOM   2009  C  CD2 . TRP A 1 287 ? -43.275 22.382  -4.688  1    117.72 ? 276 TRP A CD2 1 -0.397 0.205  -0.012 
ATOM   2010  N  NE1 . TRP A 1 287 ? -44.231 24.238  -5.51   1    112.69 ? 276 TRP A NE1 1 -0.405 0.222  -0.014 
ATOM   2011  C  CE2 . TRP A 1 287 ? -43.506 23.756  -4.454  1    111.72 ? 276 TRP A CE2 1 -0.399 0.218  -0.011 
ATOM   2012  C  CE3 . TRP A 1 287 ? -42.544 21.652  -3.743  1    110.09 ? 276 TRP A CE3 1 -0.39  0.198  -0.009 
ATOM   2013  C  CZ2 . TRP A 1 287 ? -43.032 24.405  -3.323  1    111.73 ? 276 TRP A CZ2 1 -0.394 0.224  -0.008 
ATOM   2014  C  CZ3 . TRP A 1 287 ? -42.072 22.3    -2.632  1    112.27 ? 276 TRP A CZ3 1 -0.386 0.204  -0.007 
ATOM   2015  C  CH2 . TRP A 1 287 ? -42.319 23.663  -2.426  1    115.66 ? 276 TRP A CH2 1 -0.388 0.217  -0.006 
ATOM   2016  N  N   . HIS A 1 288 ? -45.844 18.283  -7.689  1    120.08 ? 277 HIS A N   1 -0.42  0.168  -0.019 
ATOM   2017  C  CA  . HIS A 1 288 ? -45.892 17.205  -8.669  1    116.36 ? 277 HIS A CA  1 -0.421 0.158  -0.022 
ATOM   2018  C  C   . HIS A 1 288 ? -45.73  17.803  -10.055 1    107.75 ? 277 HIS A C   1 -0.419 0.163  -0.025 
ATOM   2019  O  O   . HIS A 1 288 ? -46.297 18.858  -10.353 1    108.68 ? 277 HIS A O   1 -0.424 0.173  -0.026 
ATOM   2020  C  CB  . HIS A 1 288 ? -47.204 16.417  -8.602  1    114.37 ? 277 HIS A CB  1 -0.433 0.15   -0.021 
ATOM   2021  C  CG  . HIS A 1 288 ? -47.681 16.163  -7.207  1    122.44 ? 277 HIS A CG  1 -0.437 0.148  -0.018 
ATOM   2022  N  ND1 . HIS A 1 288 ? -47.448 14.978  -6.543  1    123.62 ? 277 HIS A ND1 1 -0.435 0.137  -0.016 
ATOM   2023  C  CD2 . HIS A 1 288 ? -48.374 16.948  -6.346  1    115.83 ? 277 HIS A CD2 1 -0.443 0.155  -0.016 
ATOM   2024  C  CE1 . HIS A 1 288 ? -47.982 15.04   -5.336  1    118.65 ? 277 HIS A CE1 1 -0.44  0.138  -0.013 
ATOM   2025  N  NE2 . HIS A 1 288 ? -48.553 16.224  -5.193  1    118.33 ? 277 HIS A NE2 1 -0.445 0.149  -0.013 
ATOM   2026  N  N   . HIS A 1 289 ? -44.927 17.134  -10.882 1    113.44 ? 278 HIS A N   1 -0.412 0.157  -0.027 
ATOM   2027  C  CA  . HIS A 1 289 ? -44.794 17.453  -12.305 1    113.91 ? 278 HIS A CA  1 -0.41  0.16   -0.031 
ATOM   2028  C  C   . HIS A 1 289 ? -44.683 16.115  -13.027 1    110.46 ? 278 HIS A C   1 -0.409 0.148  -0.033 
ATOM   2029  O  O   . HIS A 1 289 ? -43.636 15.46   -12.971 1    108.04 ? 278 HIS A O   1 -0.4   0.142  -0.032 
ATOM   2030  C  CB  . HIS A 1 289 ? -43.59  18.346  -12.579 1    107.25 ? 278 HIS A CB  1 -0.399 0.168  -0.031 
ATOM   2031  C  CG  . HIS A 1 289 ? -43.41  18.689  -14.017 1    113.31 ? 278 HIS A CG  1 -0.398 0.171  -0.035 
ATOM   2032  N  ND1 . HIS A 1 289 ? -42.33  18.253  -14.753 1    119.11 ? 278 HIS A ND1 1 -0.388 0.167  -0.037 
ATOM   2033  C  CD2 . HIS A 1 289 ? -44.176 19.419  -14.864 1    122.58 ? 278 HIS A CD2 1 -0.405 0.178  -0.037 
ATOM   2034  C  CE1 . HIS A 1 289 ? -42.438 18.701  -15.993 1    120.49 ? 278 HIS A CE1 1 -0.389 0.171  -0.04  
ATOM   2035  N  NE2 . HIS A 1 289 ? -43.548 19.413  -16.086 1    119.11 ? 278 HIS A NE2 1 -0.399 0.178  -0.04  
ATOM   2036  N  N   . ASN A 1 290 ? -45.778 15.708  -13.679 1    110.14 ? 279 ASN A N   1 -0.42  0.144  -0.034 
ATOM   2037  C  CA  . ASN A 1 290 ? -45.9   14.394  -14.307 1    109.73 ? 279 ASN A CA  1 -0.421 0.132  -0.036 
ATOM   2038  C  C   . ASN A 1 290 ? -45.702 13.264  -13.3   1    108.78 ? 279 ASN A C   1 -0.419 0.122  -0.033 
ATOM   2039  O  O   . ASN A 1 290 ? -46.615 12.964  -12.522 1    118.14 ? 279 ASN A O   1 -0.427 0.119  -0.031 
ATOM   2040  C  CB  . ASN A 1 290 ? -44.927 14.276  -15.484 1    113.47 ? 279 ASN A CB  1 -0.412 0.131  -0.039 
ATOM   2041  C  CG  . ASN A 1 290 ? -45.373 15.1    -16.691 1    115.23 ? 279 ASN A CG  1 -0.416 0.138  -0.042 
ATOM   2042  O  OD1 . ASN A 1 290 ? -46.494 14.937  -17.205 1    115.79 ? 279 ASN A OD1 1 -0.426 0.137  -0.043 
ATOM   2043  N  ND2 . ASN A 1 290 ? -44.502 16.004  -17.139 1    116.52 ? 279 ASN A ND2 1 -0.408 0.147  -0.043 
ATOM   2044  N  N   . ASN A 1 291 ? -44.536 12.622  -13.286 1    102.14 ? 280 ASN A N   1 -0.408 0.116  -0.033 
ATOM   2045  C  CA  . ASN A 1 291 ? -44.329 11.499  -12.376 1    112.02 ? 280 ASN A CA  1 -0.406 0.105  -0.031 
ATOM   2046  C  C   . ASN A 1 291 ? -43.29  11.768  -11.278 1    111.09 ? 280 ASN A C   1 -0.397 0.108  -0.028 
ATOM   2047  O  O   . ASN A 1 291 ? -42.878 10.83   -10.579 1    102.73 ? 280 ASN A O   1 -0.393 0.099  -0.026 
ATOM   2048  C  CB  . ASN A 1 291 ? -43.957 10.252  -13.176 1    110.5  ? 280 ASN A CB  1 -0.403 0.094  -0.033 
ATOM   2049  C  CG  . ASN A 1 291 ? -45.171 9.553   -13.755 1    117.06 ? 280 ASN A CG  1 -0.414 0.088  -0.034 
ATOM   2050  O  OD1 . ASN A 1 291 ? -46.3   9.775   -13.298 1    118.05 ? 280 ASN A OD1 1 -0.424 0.09   -0.033 
ATOM   2051  N  ND2 . ASN A 1 291 ? -44.95  8.697   -14.762 1    119.1  ? 280 ASN A ND2 1 -0.412 0.08   -0.037 
ATOM   2052  N  N   . LEU A 1 292 ? -42.874 13.02   -11.098 1    110.13 ? 281 LEU A N   1 -0.393 0.119  -0.028 
ATOM   2053  C  CA  . LEU A 1 292 ? -41.863 13.4    -10.12  1    110.8  ? 281 LEU A CA  1 -0.384 0.123  -0.025 
ATOM   2054  C  C   . LEU A 1 292 ? -42.52  14.143  -8.962  1    110.3  ? 281 LEU A C   1 -0.39  0.13   -0.022 
ATOM   2055  O  O   . LEU A 1 292 ? -43.293 15.082  -9.174  1    110.94 ? 281 LEU A O   1 -0.397 0.138  -0.023 
ATOM   2056  C  CB  . LEU A 1 292 ? -40.784 14.277  -10.761 1    109.74 ? 281 LEU A CB  1 -0.374 0.131  -0.027 
ATOM   2057  C  CG  . LEU A 1 292 ? -40.054 15.283  -9.87   1    107.16 ? 281 LEU A CG  1 -0.367 0.14   -0.025 
ATOM   2058  C  CD1 . LEU A 1 292 ? -39.237 14.553  -8.829  1    105.14 ? 281 LEU A CD1 1 -0.36  0.133  -0.022 
ATOM   2059  C  CD2 . LEU A 1 292 ? -39.164 16.165  -10.731 1    105.85 ? 281 LEU A CD2 1 -0.359 0.148  -0.027 
ATOM   2060  N  N   . ASN A 1 293 ? -42.208 13.723  -7.744  1    110.6  ? 282 ASN A N   1 -0.387 0.126  -0.019 
ATOM   2061  C  CA  . ASN A 1 293 ? -42.725 14.358  -6.543  1    111.86 ? 282 ASN A CA  1 -0.392 0.132  -0.016 
ATOM   2062  C  C   . ASN A 1 293 ? -41.564 14.946  -5.756  1    106.47 ? 282 ASN A C   1 -0.381 0.137  -0.014 
ATOM   2063  O  O   . ASN A 1 293 ? -40.6   14.239  -5.434  1    103.43 ? 282 ASN A O   1 -0.372 0.13   -0.014 
ATOM   2064  C  CB  . ASN A 1 293 ? -43.513 13.358  -5.69   1    112.64 ? 282 ASN A CB  1 -0.399 0.122  -0.014 
ATOM   2065  C  CG  . ASN A 1 293 ? -44.878 13.035  -6.276  1    119.06 ? 282 ASN A CG  1 -0.411 0.119  -0.016 
ATOM   2066  O  OD1 . ASN A 1 293 ? -45.141 13.274  -7.471  1    109.21 ? 282 ASN A OD1 1 -0.414 0.122  -0.019 
ATOM   2067  N  ND2 . ASN A 1 293 ? -45.767 12.498  -5.43   1    119.79 ? 282 ASN A ND2 1 -0.419 0.115  -0.014 
ATOM   2068  N  N   . TYR A 1 294 ? -41.659 16.24   -5.454  1    105.39 ? 283 TYR A N   1 -0.382 0.149  -0.014 
ATOM   2069  C  CA  . TYR A 1 294 ? -40.603 16.978  -4.765  1    109.28 ? 283 TYR A CA  1 -0.372 0.156  -0.012 
ATOM   2070  C  C   . TYR A 1 294 ? -41.142 17.534  -3.451  1    107.71 ? 283 TYR A C   1 -0.377 0.161  -0.009 
ATOM   2071  O  O   . TYR A 1 294 ? -41.991 18.435  -3.458  1    105.52 ? 283 TYR A O   1 -0.385 0.169  -0.009 
ATOM   2072  C  CB  . TYR A 1 294 ? -40.071 18.095  -5.656  1    106.43 ? 283 TYR A CB  1 -0.367 0.166  -0.014 
ATOM   2073  C  CG  . TYR A 1 294 ? -38.939 18.893  -5.058  1    105.51 ? 283 TYR A CG  1 -0.357 0.173  -0.013 
ATOM   2074  C  CD1 . TYR A 1 294 ? -37.708 18.307  -4.806  1    105.57 ? 283 TYR A CD1 1 -0.346 0.168  -0.012 
ATOM   2075  C  CD2 . TYR A 1 294 ? -39.096 20.243  -4.769  1    102.08 ? 283 TYR A CD2 1 -0.358 0.186  -0.012 
ATOM   2076  C  CE1 . TYR A 1 294 ? -36.665 19.039  -4.279  1    103.9  ? 283 TYR A CE1 1 -0.336 0.174  -0.011 
ATOM   2077  C  CE2 . TYR A 1 294 ? -38.062 20.986  -4.247  1    101.3  ? 283 TYR A CE2 1 -0.349 0.192  -0.011 
ATOM   2078  C  CZ  . TYR A 1 294 ? -36.845 20.381  -3.999  1    101.86 ? 283 TYR A CZ  1 -0.338 0.187  -0.01  
ATOM   2079  O  OH  . TYR A 1 294 ? -35.809 21.122  -3.471  1    95.66  ? 283 TYR A OH  1 -0.328 0.194  -0.009 
ATOM   2080  N  N   . TYR A 1 295 ? -40.632 17.008  -2.332  1    112.72 ? 284 TYR A N   1 -0.372 0.156  -0.006 
ATOM   2081  C  CA  . TYR A 1 295 ? -40.981 17.457  -0.984  1    107.43 ? 284 TYR A CA  1 -0.376 0.16   -0.002 
ATOM   2082  C  C   . TYR A 1 295 ? -39.889 18.375  -0.45   1    102.56 ? 284 TYR A C   1 -0.366 0.168  -0.001 
ATOM   2083  O  O   . TYR A 1 295 ? -38.716 17.995  -0.438  1    102.91 ? 284 TYR A O   1 -0.355 0.165  -0.001 
ATOM   2084  C  CB  . TYR A 1 295 ? -41.141 16.264  -0.045  1    103.76 ? 284 TYR A CB  1 -0.377 0.149  -0.0   
ATOM   2085  C  CG  . TYR A 1 295 ? -42.252 15.31   -0.412  1    111.47 ? 284 TYR A CG  1 -0.387 0.14   -0.001 
ATOM   2086  C  CD1 . TYR A 1 295 ? -42.124 14.401  -1.476  1    111.35 ? 284 TYR A CD1 1 -0.386 0.132  -0.004 
ATOM   2087  C  CD2 . TYR A 1 295 ? -43.427 15.298  0.321   1    112.65 ? 284 TYR A CD2 1 -0.398 0.14   0.001  
ATOM   2088  C  CE1 . TYR A 1 295 ? -43.156 13.522  -1.787  1    108.05 ? 284 TYR A CE1 1 -0.395 0.124  -0.004 
ATOM   2089  C  CE2 . TYR A 1 295 ? -44.45  14.427  0.019   1    115.65 ? 284 TYR A CE2 1 -0.407 0.132  0.0    
ATOM   2090  C  CZ  . TYR A 1 295 ? -44.316 13.549  -1.029  1    111.76 ? 284 TYR A CZ  1 -0.406 0.124  -0.003 
ATOM   2091  O  OH  . TYR A 1 295 ? -45.366 12.711  -1.288  1    111.7  ? 284 TYR A OH  1 -0.416 0.116  -0.003 
ATOM   2092  N  N   . ALA A 1 296 ? -40.274 19.565  0.01    1    103.31 ? 285 ALA A N   1 -0.369 0.179  0.0    
ATOM   2093  C  CA  . ALA A 1 296 ? -39.328 20.539  0.565   1    107.19 ? 285 ALA A CA  1 -0.36  0.188  0.001  
ATOM   2094  C  C   . ALA A 1 296 ? -39.47  20.621  2.091   1    111.66 ? 285 ALA A C   1 -0.362 0.189  0.005  
ATOM   2095  O  O   . ALA A 1 296 ? -40.315 21.365  2.604   1    115.86 ? 285 ALA A O   1 -0.369 0.196  0.007  
ATOM   2096  C  CB  . ALA A 1 296 ? -39.536 21.905  -0.08   1    103.38 ? 285 ALA A CB  1 -0.362 0.201  -0.0   
ATOM   2097  N  N   . VAL A 1 297 ? -38.625 19.874  2.814   1    106.88 ? 286 VAL A N   1 -0.354 0.182  0.007  
ATOM   2098  C  CA  . VAL A 1 297 ? -38.521 19.948  4.275   1    103.69 ? 286 VAL A CA  1 -0.353 0.183  0.011  
ATOM   2099  C  C   . VAL A 1 297 ? -37.698 21.165  4.687   1    105.91 ? 286 VAL A C   1 -0.345 0.194  0.012  
ATOM   2100  O  O   . VAL A 1 297 ? -36.465 21.085  4.784   1    105.17 ? 286 VAL A O   1 -0.334 0.193  0.012  
ATOM   2101  C  CB  . VAL A 1 297 ? -37.878 18.672  4.852   1    103.51 ? 286 VAL A CB  1 -0.347 0.171  0.012  
ATOM   2102  C  CG1 . VAL A 1 297 ? -37.644 18.816  6.366   1    107.74 ? 286 VAL A CG1 1 -0.345 0.172  0.016  
ATOM   2103  C  CG2 . VAL A 1 297 ? -38.702 17.436  4.518   1    99.18  ? 286 VAL A CG2 1 -0.355 0.16   0.011  
ATOM   2104  N  N   . ASP A 1 298 ? -38.353 22.297  4.95    1    107.28 ? 287 ASP A N   1 -0.351 0.204  0.012  
ATOM   2105  C  CA  . ASP A 1 298 ? -37.62  23.514  5.293   1    109.95 ? 287 ASP A CA  1 -0.345 0.215  0.013  
ATOM   2106  C  C   . ASP A 1 298 ? -37.325 23.541  6.783   1    105.56 ? 287 ASP A C   1 -0.342 0.216  0.017  
ATOM   2107  O  O   . ASP A 1 298 ? -38.247 23.559  7.601   1    111.76 ? 287 ASP A O   1 -0.351 0.216  0.019  
ATOM   2108  C  CB  . ASP A 1 298 ? -38.376 24.778  4.908   1    110.88 ? 287 ASP A CB  1 -0.352 0.227  0.012  
ATOM   2109  C  CG  . ASP A 1 298 ? -37.491 26.026  4.982   1    108.22 ? 287 ASP A CG  1 -0.344 0.239  0.012  
ATOM   2110  O  OD1 . ASP A 1 298 ? -36.357 25.942  5.517   1    102.34 ? 287 ASP A OD1 1 -0.333 0.238  0.014  
ATOM   2111  O  OD2 . ASP A 1 298 ? -37.922 27.085  4.474   1    110.5  ? 287 ASP A OD2 1 -0.348 0.248  0.011  
ATOM   2112  N  N   . LEU A 1 299 ? -36.041 23.605  7.129   1    104.77 ? 288 LEU A N   1 -0.33  0.216  0.018  
ATOM   2113  C  CA  . LEU A 1 299 ? -35.644 23.512  8.53    1    106.54 ? 288 LEU A CA  1 -0.327 0.215  0.021  
ATOM   2114  C  C   . LEU A 1 299 ? -36.039 24.741  9.348   1    108.84 ? 288 LEU A C   1 -0.33  0.227  0.023  
ATOM   2115  O  O   . LEU A 1 299 ? -36.152 24.632  10.572  1    114.04 ? 288 LEU A O   1 -0.331 0.226  0.026  
ATOM   2116  C  CB  . LEU A 1 299 ? -34.134 23.252  8.634   1    98.37  ? 288 LEU A CB  1 -0.313 0.213  0.022  
ATOM   2117  C  CG  . LEU A 1 299 ? -33.665 21.95   7.975   1    96.62  ? 288 LEU A CG  1 -0.309 0.201  0.02   
ATOM   2118  C  CD1 . LEU A 1 299 ? -32.265 21.539  8.392   1    87.15  ? 288 LEU A CD1 1 -0.296 0.197  0.021  
ATOM   2119  C  CD2 . LEU A 1 299 ? -34.672 20.84   8.259   1    105.73 ? 288 LEU A CD2 1 -0.318 0.191  0.021  
ATOM   2120  N  N   . SER A 1 300 ? -36.264 25.896  8.722   1    104.98 ? 289 SER A N   1 -0.332 0.237  0.022  
ATOM   2121  C  CA  . SER A 1 300 ? -36.821 27.018  9.469   1    106.2  ? 289 SER A CA  1 -0.337 0.248  0.024  
ATOM   2122  C  C   . SER A 1 300 ? -38.223 26.696  9.972   1    109.47 ? 289 SER A C   1 -0.35  0.245  0.025  
ATOM   2123  O  O   . SER A 1 300 ? -38.51  26.819  11.166  1    115.62 ? 289 SER A O   1 -0.353 0.246  0.028  
ATOM   2124  C  CB  . SER A 1 300 ? -36.855 28.267  8.599   1    108.61 ? 289 SER A CB  1 -0.338 0.259  0.021  
ATOM   2125  O  OG  . SER A 1 300 ? -37.917 28.181  7.66    1    115.21 ? 289 SER A OG  1 -0.347 0.258  0.019  
ATOM   2126  N  N   . LEU A 1 301 ? -39.118 26.275  9.077   1    108.09 ? 290 LEU A N   1 -0.358 0.241  0.023  
ATOM   2127  C  CA  . LEU A 1 301 ? -40.49  26.028  9.505   1    112.95 ? 290 LEU A CA  1 -0.371 0.239  0.024  
ATOM   2128  C  C   . LEU A 1 301 ? -40.605 24.755  10.336  1    114    ? 290 LEU A C   1 -0.372 0.227  0.026  
ATOM   2129  O  O   . LEU A 1 301 ? -41.521 24.636  11.159  1    114.07 ? 290 LEU A O   1 -0.381 0.226  0.028  
ATOM   2130  C  CB  . LEU A 1 301 ? -41.424 25.956  8.299   1    116.95 ? 290 LEU A CB  1 -0.38  0.238  0.021  
ATOM   2131  C  CG  . LEU A 1 301 ? -41.561 27.13   7.322   1    112.17 ? 290 LEU A CG  1 -0.381 0.249  0.018  
ATOM   2132  C  CD1 . LEU A 1 301 ? -41.499 28.488  8.009   1    101.36 ? 290 LEU A CD1 1 -0.38  0.261  0.02   
ATOM   2133  C  CD2 . LEU A 1 301 ? -40.524 27.021  6.234   1    112.87 ? 290 LEU A CD2 1 -0.371 0.248  0.016  
ATOM   2134  N  N   . THR A 1 302 ? -39.693 23.806  10.151  1    111.3  ? 291 THR A N   1 -0.364 0.218  0.025  
ATOM   2135  C  CA  . THR A 1 302 ? -39.701 22.552  10.901  1    113.45 ? 291 THR A CA  1 -0.364 0.207  0.027  
ATOM   2136  C  C   . THR A 1 302 ? -38.641 22.634  12      1    120.24 ? 291 THR A C   1 -0.354 0.207  0.03   
ATOM   2137  O  O   . THR A 1 302 ? -37.44  22.484  11.746  1    116.8  ? 291 THR A O   1 -0.343 0.206  0.029  
ATOM   2138  C  CB  . THR A 1 302 ? -39.477 21.362  9.967   1    117.39 ? 291 THR A CB  1 -0.362 0.196  0.025  
ATOM   2139  O  OG1 . THR A 1 302 ? -40.642 21.168  9.14    1    108.89 ? 291 THR A OG1 1 -0.372 0.194  0.023  
ATOM   2140  C  CG2 . THR A 1 302 ? -39.17  20.078  10.773  1    111.18 ? 291 THR A CG2 1 -0.359 0.184  0.027  
ATOM   2141  N  N   . SER A 1 303 ? -39.1   22.892  13.224  1    123.22 ? 292 SER A N   1 -0.358 0.21   0.033  
ATOM   2142  C  CA  . SER A 1 303 ? -38.287 22.905  14.43   1    116.8  ? 292 SER A CA  1 -0.351 0.21   0.036  
ATOM   2143  C  C   . SER A 1 303 ? -38.645 21.686  15.275  1    120.93 ? 292 SER A C   1 -0.354 0.199  0.038  
ATOM   2144  O  O   . SER A 1 303 ? -39.667 21.027  15.049  1    118.64 ? 292 SER A O   1 -0.364 0.193  0.038  
ATOM   2145  C  CB  . SER A 1 303 ? -38.511 24.209  15.204  1    124.06 ? 292 SER A CB  1 -0.353 0.222  0.038  
ATOM   2146  O  OG  . SER A 1 303 ? -38.599 25.32   14.313  1    115.56 ? 292 SER A OG  1 -0.354 0.232  0.036  
ATOM   2147  N  N   . ARG A 1 304 ? -37.797 21.376  16.257  1    121.69 ? 293 ARG A N   1 -0.346 0.196  0.041  
ATOM   2148  C  CA  . ARG A 1 304 ? -37.885 20.082  16.919  1    117.82 ? 293 ARG A CA  1 -0.347 0.184  0.042  
ATOM   2149  C  C   . ARG A 1 304 ? -38.599 20.17   18.262  1    120.95 ? 293 ARG A C   1 -0.354 0.185  0.046  
ATOM   2150  O  O   . ARG A 1 304 ? -38.539 21.186  18.96   1    124.58 ? 293 ARG A O   1 -0.353 0.194  0.047  
ATOM   2151  C  CB  . ARG A 1 304 ? -36.502 19.458  17.094  1    113.01 ? 293 ARG A CB  1 -0.335 0.178  0.043  
ATOM   2152  C  CG  . ARG A 1 304 ? -35.54  20.227  17.949  1    120.69 ? 293 ARG A CG  1 -0.326 0.185  0.045  
ATOM   2153  C  CD  . ARG A 1 304 ? -34.683 19.23   18.707  1    121.37 ? 293 ARG A CD  1 -0.318 0.176  0.047  
ATOM   2154  N  NE  . ARG A 1 304 ? -34.198 18.172  17.829  1    117.22 ? 293 ARG A NE  1 -0.313 0.167  0.045  
ATOM   2155  C  CZ  . ARG A 1 304 ? -32.94  18.069  17.426  1    113.61 ? 293 ARG A CZ  1 -0.302 0.166  0.044  
ATOM   2156  N  NH1 . ARG A 1 304 ? -32.014 18.921  17.844  1    116.41 ? 293 ARG A NH1 1 -0.293 0.173  0.045  
ATOM   2157  N  NH2 . ARG A 1 304 ? -32.6   17.086  16.594  1    100.88 ? 293 ARG A NH2 1 -0.299 0.157  0.041  
ATOM   2158  N  N   A LYS A 1 305 ? -39.293 19.088  18.62   0.37 121.44 ? 294 LYS A N   1 -0.36  0.175  0.046  
ATOM   2159  N  N   B LYS A 1 305 ? -39.251 19.064  18.62   0.63 121.57 ? 294 LYS A N   1 -0.36  0.175  0.046  
ATOM   2160  C  CA  A LYS A 1 305 ? -40.147 19.05   19.812  0.37 117.86 ? 294 LYS A CA  1 -0.368 0.175  0.049  
ATOM   2161  C  CA  B LYS A 1 305 ? -40.112 18.946  19.796  0.63 116.24 ? 294 LYS A CA  1 -0.368 0.174  0.049  
ATOM   2162  C  C   A LYS A 1 305 ? -39.354 18.435  20.959  0.37 119.4  ? 294 LYS A C   1 -0.361 0.169  0.052  
ATOM   2163  C  C   B LYS A 1 305 ? -39.276 18.389  20.936  0.63 118.68 ? 294 LYS A C   1 -0.36  0.169  0.052  
ATOM   2164  O  O   A LYS A 1 305 ? -39.393 17.226  21.191  0.37 118.44 ? 294 LYS A O   1 -0.361 0.158  0.053  
ATOM   2165  O  O   B LYS A 1 305 ? -39.188 17.174  21.135  0.63 118.41 ? 294 LYS A O   1 -0.359 0.157  0.053  
ATOM   2166  C  CB  A LYS A 1 305 ? -41.431 18.272  19.547  0.37 115.81 ? 294 LYS A CB  1 -0.38  0.167  0.049  
ATOM   2167  C  CB  B LYS A 1 305 ? -41.306 18.052  19.468  0.63 115.79 ? 294 LYS A CB  1 -0.379 0.165  0.049  
ATOM   2168  C  CG  A LYS A 1 305 ? -42.487 18.425  20.633  0.37 116.77 ? 294 LYS A CG  1 -0.389 0.169  0.052  
ATOM   2169  C  CG  B LYS A 1 305 ? -42.109 17.526  20.636  0.63 116.56 ? 294 LYS A CG  1 -0.386 0.161  0.052  
ATOM   2170  C  CD  A LYS A 1 305 ? -43.09  19.826  20.634  0.37 115.78 ? 294 LYS A CD  1 -0.395 0.182  0.052  
ATOM   2171  C  CD  B LYS A 1 305 ? -42.61  16.119  20.327  0.63 114.86 ? 294 LYS A CD  1 -0.39  0.148  0.051  
ATOM   2172  C  CE  A LYS A 1 305 ? -43.821 20.121  19.324  0.37 111.34 ? 294 LYS A CE  1 -0.402 0.184  0.048  
ATOM   2173  C  CE  B LYS A 1 305 ? -43.306 16.047  18.969  0.63 104.51 ? 294 LYS A CE  1 -0.397 0.147  0.047  
ATOM   2174  N  NZ  A LYS A 1 305 ? -44.985 19.216  19.11   0.37 105.4  ? 294 LYS A NZ  1 -0.412 0.176  0.048  
ATOM   2175  N  NZ  B LYS A 1 305 ? -44.421 17.032  18.8    0.63 97.08  ? 294 LYS A NZ  1 -0.407 0.156  0.047  
ATOM   2176  N  N   . SER A 1 306 ? -38.63  19.293  21.68   1    122.38 ? 295 SER A N   1 -0.354 0.177  0.054  
ATOM   2177  C  CA  . SER A 1 306 ? -37.893 18.935  22.892  1    122.38 ? 295 SER A CA  1 -0.347 0.174  0.057  
ATOM   2178  C  C   . SER A 1 306 ? -36.933 17.766  22.69   1    122.17 ? 295 SER A C   1 -0.338 0.163  0.057  
ATOM   2179  O  O   . SER A 1 306 ? -35.77  17.971  22.329  1    128.69 ? 295 SER A O   1 -0.328 0.165  0.056  
ATOM   2180  C  CB  . SER A 1 306 ? -38.866 18.621  24.036  1    120.8  ? 295 SER A CB  1 -0.356 0.171  0.06   
ATOM   2181  O  OG  . SER A 1 306 ? -38.164 18.228  25.205  1    120.93 ? 295 SER A OG  1 -0.35  0.167  0.063  
ATOM   2182  N  N   . VAL A 1 307 ? -37.411 16.546  22.921  1    117.29 ? 296 VAL A N   1 -0.343 0.152  0.057  
ATOM   2183  C  CA  . VAL A 1 307 ? -36.589 15.349  22.819  1    115.96 ? 296 VAL A CA  1 -0.335 0.141  0.057  
ATOM   2184  C  C   . VAL A 1 307 ? -37.104 14.495  21.678  1    119.72 ? 296 VAL A C   1 -0.34  0.133  0.054  
ATOM   2185  O  O   . VAL A 1 307 ? -38.246 14.629  21.222  1    122.47 ? 296 VAL A O   1 -0.35  0.134  0.053  
ATOM   2186  C  CB  . VAL A 1 307 ? -36.577 14.543  24.13   1    117.95 ? 296 VAL A CB  1 -0.335 0.133  0.06   
ATOM   2187  C  CG1 . VAL A 1 307 ? -35.607 15.17   25.122  1    117.07 ? 296 VAL A CG1 1 -0.326 0.139  0.063  
ATOM   2188  C  CG2 . VAL A 1 307 ? -37.982 14.479  24.702  1    119.69 ? 296 VAL A CG2 1 -0.348 0.133  0.062  
ATOM   2189  N  N   . GLY A 1 308 ? -36.251 13.587  21.227  1    115.35 ? 297 GLY A N   1 -0.332 0.125  0.053  
ATOM   2190  C  CA  . GLY A 1 308 ? -36.584 12.761  20.09   1    112.68 ? 297 GLY A CA  1 -0.335 0.117  0.05   
ATOM   2191  C  C   . GLY A 1 308 ? -35.876 13.221  18.828  1    109.01 ? 297 GLY A C   1 -0.329 0.121  0.047  
ATOM   2192  O  O   . GLY A 1 308 ? -35.394 14.355  18.72   1    108.19 ? 297 GLY A O   1 -0.324 0.132  0.047  
ATOM   2193  N  N   . VAL A 1 309 ? -35.795 12.297  17.863  1    108.65 ? 298 VAL A N   1 -0.328 0.113  0.045  
ATOM   2194  C  CA  . VAL A 1 309 ? -35.156 12.591  16.588  1    100.16 ? 298 VAL A CA  1 -0.322 0.115  0.041  
ATOM   2195  C  C   . VAL A 1 309 ? -35.867 13.755  15.921  1    97.48  ? 298 VAL A C   1 -0.329 0.126  0.04   
ATOM   2196  O  O   . VAL A 1 309 ? -37.105 13.83   15.908  1    96.27  ? 298 VAL A O   1 -0.34  0.127  0.04   
ATOM   2197  C  CB  . VAL A 1 309 ? -35.161 11.339  15.692  1    104.59 ? 298 VAL A CB  1 -0.322 0.104  0.039  
ATOM   2198  C  CG1 . VAL A 1 309 ? -34.616 11.652  14.323  1    105.35 ? 298 VAL A CG1 1 -0.317 0.107  0.036  
ATOM   2199  C  CG2 . VAL A 1 309 ? -34.333 10.236  16.326  1    107.64 ? 298 VAL A CG2 1 -0.315 0.094  0.041  
ATOM   2200  N  N   . HIS A 1 310 ? -35.073 14.694  15.388  1    102.63 ? 299 HIS A N   1 -0.321 0.135  0.038  
ATOM   2201  C  CA  . HIS A 1 310 ? -35.517 15.867  14.63   1    104.14 ? 299 HIS A CA  1 -0.325 0.145  0.037  
ATOM   2202  C  C   . HIS A 1 310 ? -36.657 15.543  13.667  1    103.04 ? 299 HIS A C   1 -0.336 0.142  0.034  
ATOM   2203  O  O   . HIS A 1 310 ? -36.568 14.563  12.909  1    98.89  ? 299 HIS A O   1 -0.335 0.133  0.032  
ATOM   2204  C  CB  . HIS A 1 310 ? -34.339 16.456  13.853  1    98.49  ? 299 HIS A CB  1 -0.315 0.151  0.035  
ATOM   2205  C  CG  . HIS A 1 310 ? -34.558 17.864  13.407  1    100.75 ? 299 HIS A CG  1 -0.317 0.164  0.033  
ATOM   2206  N  ND1 . HIS A 1 310 ? -35.556 18.219  12.529  1    105.43 ? 299 HIS A ND1 1 -0.326 0.167  0.031  
ATOM   2207  C  CD2 . HIS A 1 310 ? -33.903 19.009  13.711  1    104.09 ? 299 HIS A CD2 1 -0.311 0.174  0.034  
ATOM   2208  C  CE1 . HIS A 1 310 ? -35.518 19.522  12.321  1    108.02 ? 299 HIS A CE1 1 -0.325 0.179  0.031  
ATOM   2209  N  NE2 . HIS A 1 310 ? -34.519 20.026  13.022  1    102.65 ? 299 HIS A NE2 1 -0.316 0.184  0.033  
ATOM   2210  N  N   . PRO A 1 311 ? -37.73  16.346  13.65   1    104.71 ? 300 PRO A N   1 -0.346 0.15   0.034  
ATOM   2211  C  CA  . PRO A 1 311 ? -38.891 16.014  12.795  1    106.71 ? 300 PRO A CA  1 -0.356 0.147  0.032  
ATOM   2212  C  C   . PRO A 1 311 ? -38.566 15.946  11.315  1    107.99 ? 300 PRO A C   1 -0.353 0.146  0.028  
ATOM   2213  O  O   . PRO A 1 311 ? -39.28  15.257  10.573  1    108.56 ? 300 PRO A O   1 -0.36  0.14   0.026  
ATOM   2214  C  CB  . PRO A 1 311 ? -39.887 17.148  13.091  1    106.91 ? 300 PRO A CB  1 -0.366 0.157  0.033  
ATOM   2215  C  CG  . PRO A 1 311 ? -39.428 17.759  14.38   1    111.24 ? 300 PRO A CG  1 -0.361 0.163  0.036  
ATOM   2216  C  CD  . PRO A 1 311 ? -37.937 17.597  14.397  1    106.44 ? 300 PRO A CD  1 -0.348 0.161  0.036  
ATOM   2217  N  N   . ALA A 1 312 ? -37.515 16.641  10.865  1    107.8  ? 301 ALA A N   1 -0.344 0.153  0.027  
ATOM   2218  C  CA  . ALA A 1 312 ? -37.146 16.625  9.449   1    109.28 ? 301 ALA A CA  1 -0.34  0.152  0.024  
ATOM   2219  C  C   . ALA A 1 312 ? -36.796 15.219  8.977   1    105.88 ? 301 ALA A C   1 -0.337 0.139  0.022  
ATOM   2220  O  O   . ALA A 1 312 ? -37.263 14.777  7.921   1    106.68 ? 301 ALA A O   1 -0.341 0.135  0.02   
ATOM   2221  C  CB  . ALA A 1 312 ? -35.975 17.574  9.201   1    108.68 ? 301 ALA A CB  1 -0.33  0.161  0.023  
ATOM   2222  N  N   . LEU A 1 313 ? -35.957 14.502  9.735   1    101.32 ? 302 LEU A N   1 -0.33  0.133  0.024  
ATOM   2223  C  CA  . LEU A 1 313 ? -35.597 13.144  9.352   1    99.26  ? 302 LEU A CA  1 -0.326 0.12   0.023  
ATOM   2224  C  C   . LEU A 1 313 ? -36.63  12.108  9.762   1    103.09 ? 302 LEU A C   1 -0.336 0.111  0.024  
ATOM   2225  O  O   . LEU A 1 313 ? -36.525 10.957  9.331   1    106.04 ? 302 LEU A O   1 -0.335 0.1    0.023  
ATOM   2226  C  CB  . LEU A 1 313 ? -34.259 12.735  9.948   1    90.91  ? 302 LEU A CB  1 -0.314 0.117  0.025  
ATOM   2227  C  CG  . LEU A 1 313 ? -33.16  13.766  9.881   1    99.79  ? 302 LEU A CG  1 -0.304 0.126  0.025  
ATOM   2228  C  CD1 . LEU A 1 313 ? -33.163 14.483  11.193  1    110.05 ? 302 LEU A CD1 1 -0.304 0.133  0.028  
ATOM   2229  C  CD2 . LEU A 1 313 ? -31.847 13.058  9.694   1    109.86 ? 302 LEU A CD2 1 -0.292 0.12   0.024  
ATOM   2230  N  N   . LEU A 1 314 ? -37.599 12.459  10.605  1    106.3  ? 303 LEU A N   1 -0.345 0.114  0.026  
ATOM   2231  C  CA  . LEU A 1 314 ? -38.68  11.517  10.865  1    105.87 ? 303 LEU A CA  1 -0.354 0.106  0.027  
ATOM   2232  C  C   . LEU A 1 314 ? -39.61  11.446  9.664   1    107.96 ? 303 LEU A C   1 -0.363 0.105  0.024  
ATOM   2233  O  O   . LEU A 1 314 ? -40.08  10.362  9.294   1    110.66 ? 303 LEU A O   1 -0.367 0.095  0.023  
ATOM   2234  C  CB  . LEU A 1 314 ? -39.436 11.906  12.14   1    111.61 ? 303 LEU A CB  1 -0.361 0.109  0.03   
ATOM   2235  C  CG  . LEU A 1 314 ? -38.764 11.754  13.525  1    107.16 ? 303 LEU A CG  1 -0.355 0.108  0.034  
ATOM   2236  C  CD1 . LEU A 1 314 ? -39.728 12.189  14.634  1    108.17 ? 303 LEU A CD1 1 -0.364 0.112  0.037  
ATOM   2237  C  CD2 . LEU A 1 314 ? -38.248 10.345  13.808  1    98.77  ? 303 LEU A CD2 1 -0.351 0.095  0.034  
ATOM   2238  N  N   . PHE A 1 315 ? -39.853 12.59   9.017   1    107.49 ? 304 PHE A N   1 -0.365 0.115  0.023  
ATOM   2239  C  CA  . PHE A 1 315 ? -40.629 12.586  7.78    1    111.34 ? 304 PHE A CA  1 -0.372 0.115  0.019  
ATOM   2240  C  C   . PHE A 1 315 ? -39.869 11.896  6.654   1    109.29 ? 304 PHE A C   1 -0.365 0.109  0.017  
ATOM   2241  O  O   . PHE A 1 315 ? -40.464 11.15   5.868   1    109.26 ? 304 PHE A O   1 -0.371 0.102  0.015  
ATOM   2242  C  CB  . PHE A 1 315 ? -40.997 14.014  7.377   1    110.36 ? 304 PHE A CB  1 -0.376 0.128  0.018  
ATOM   2243  C  CG  . PHE A 1 315 ? -41.628 14.105  6.034   1    107.02 ? 304 PHE A CG  1 -0.381 0.129  0.015  
ATOM   2244  C  CD1 . PHE A 1 315 ? -42.951 13.748  5.854   1    110.69 ? 304 PHE A CD1 1 -0.394 0.126  0.015  
ATOM   2245  C  CD2 . PHE A 1 315 ? -40.893 14.526  4.94    1    112.59 ? 304 PHE A CD2 1 -0.375 0.133  0.012  
ATOM   2246  C  CE1 . PHE A 1 315 ? -43.534 13.814  4.6     1    117.02 ? 304 PHE A CE1 1 -0.399 0.127  0.011  
ATOM   2247  C  CE2 . PHE A 1 315 ? -41.471 14.589  3.677   1    110.42 ? 304 PHE A CE2 1 -0.38  0.134  0.009  
ATOM   2248  C  CZ  . PHE A 1 315 ? -42.795 14.246  3.511   1    110.4  ? 304 PHE A CZ  1 -0.392 0.131  0.009  
ATOM   2249  N  N   . ALA A 1 316 ? -38.556 12.138  6.562   1    103.7  ? 305 ALA A N   1 -0.353 0.111  0.016  
ATOM   2250  C  CA  . ALA A 1 316 ? -37.729 11.425  5.596   1    101.69 ? 305 ALA A CA  1 -0.346 0.105  0.014  
ATOM   2251  C  C   . ALA A 1 316 ? -37.931 9.919   5.696   1    107.32 ? 305 ALA A C   1 -0.348 0.091  0.014  
ATOM   2252  O  O   . ALA A 1 316 ? -37.981 9.225   4.675   1    104.12 ? 305 ALA A O   1 -0.348 0.085  0.012  
ATOM   2253  C  CB  . ALA A 1 316 ? -36.257 11.777  5.806   1    100.63 ? 305 ALA A CB  1 -0.332 0.108  0.014  
ATOM   2254  N  N   . LEU A 1 317 ? -38.072 9.399   6.92    1    111.55 ? 306 LEU A N   1 -0.349 0.086  0.017  
ATOM   2255  C  CA  . LEU A 1 317 ? -38.237 7.966   7.148   1    109.84 ? 306 LEU A CA  1 -0.35  0.073  0.018  
ATOM   2256  C  C   . LEU A 1 317 ? -39.684 7.496   7.012   1    112.91 ? 306 LEU A C   1 -0.364 0.069  0.018  
ATOM   2257  O  O   . LEU A 1 317 ? -39.923 6.388   6.521   1    108.74 ? 306 LEU A O   1 -0.366 0.059  0.016  
ATOM   2258  C  CB  . LEU A 1 317 ? -37.702 7.592   8.528   1    106.4  ? 306 LEU A CB  1 -0.346 0.07   0.021  
ATOM   2259  C  CG  . LEU A 1 317 ? -36.204 7.842   8.69    1    107.36 ? 306 LEU A CG  1 -0.332 0.072  0.022  
ATOM   2260  C  CD1 . LEU A 1 317 ? -35.681 7.202   9.953   1    110.34 ? 306 LEU A CD1 1 -0.327 0.066  0.025  
ATOM   2261  C  CD2 . LEU A 1 317 ? -35.459 7.321   7.504   1    106.93 ? 306 LEU A CD2 1 -0.325 0.067  0.019  
ATOM   2262  N  N   . GLU A 1 318 ? -40.657 8.301   7.456   1    114.05 ? 307 GLU A N   1 -0.373 0.076  0.019  
ATOM   2263  C  CA  . GLU A 1 318 ? -42.06  8.008   7.157   1    115.66 ? 307 GLU A CA  1 -0.385 0.073  0.018  
ATOM   2264  C  C   . GLU A 1 318 ? -42.294 7.848   5.647   1    117.12 ? 307 GLU A C   1 -0.388 0.072  0.014  
ATOM   2265  O  O   . GLU A 1 318 ? -43.089 7.004   5.219   1    115.86 ? 307 GLU A O   1 -0.395 0.064  0.013  
ATOM   2266  C  CB  . GLU A 1 318 ? -42.957 9.117   7.737   1    109.2  ? 307 GLU A CB  1 -0.394 0.084  0.019  
ATOM   2267  C  CG  . GLU A 1 318 ? -43.705 8.759   9.013   1    122.91 ? 307 GLU A CG  1 -0.401 0.08   0.023  
ATOM   2268  C  CD  . GLU A 1 318 ? -43.745 9.91    10.048  1    134.6  ? 307 GLU A CD  1 -0.401 0.091  0.025  
ATOM   2269  O  OE1 . GLU A 1 318 ? -43.645 11.085  9.619   1    135.63 ? 307 GLU A OE1 1 -0.4   0.102  0.024  
ATOM   2270  O  OE2 . GLU A 1 318 ? -43.877 9.641   11.279  1    117.21 ? 307 GLU A OE2 1 -0.402 0.088  0.028  
ATOM   2271  N  N   . GLN A 1 319 ? -41.603 8.649   4.822   1    113.13 ? 308 GLN A N   1 -0.381 0.079  0.012  
ATOM   2272  C  CA  . GLN A 1 319 ? -41.813 8.599   3.372   1    120.54 ? 308 GLN A CA  1 -0.383 0.079  0.008  
ATOM   2273  C  C   . GLN A 1 319 ? -41.021 7.483   2.692   1    118.76 ? 308 GLN A C   1 -0.376 0.069  0.007  
ATOM   2274  O  O   . GLN A 1 319 ? -41.462 6.96    1.658   1    119.41 ? 308 GLN A O   1 -0.38  0.064  0.004  
ATOM   2275  C  CB  . GLN A 1 319 ? -41.465 9.949   2.738   1    115.92 ? 308 GLN A CB  1 -0.38  0.091  0.007  
ATOM   2276  C  CG  . GLN A 1 319 ? -42.629 10.919  2.745   1    117.27 ? 308 GLN A CG  1 -0.391 0.1    0.007  
ATOM   2277  C  CD  . GLN A 1 319 ? -43.837 10.359  2.016   1    126.13 ? 308 GLN A CD  1 -0.402 0.095  0.005  
ATOM   2278  O  OE1 . GLN A 1 319 ? -43.783 10.079  0.806   1    126.2  ? 308 GLN A OE1 1 -0.401 0.092  0.002  
ATOM   2279  N  NE2 . GLN A 1 319 ? -44.931 10.17   2.754   1    127.24 ? 308 GLN A NE2 1 -0.412 0.093  0.007  
ATOM   2280  N  N   . LEU A 1 320 ? -39.854 7.124   3.235   1    115.85 ? 309 LEU A N   1 -0.365 0.065  0.008  
ATOM   2281  C  CA  . LEU A 1 320 ? -39.117 5.955   2.777   1    110.54 ? 309 LEU A CA  1 -0.358 0.055  0.007  
ATOM   2282  C  C   . LEU A 1 320 ? -39.659 4.678   3.393   1    108.68 ? 309 LEU A C   1 -0.363 0.043  0.008  
ATOM   2283  O  O   . LEU A 1 320 ? -39.449 3.6     2.836   1    108.04 ? 309 LEU A O   1 -0.362 0.033  0.007  
ATOM   2284  C  CB  . LEU A 1 320 ? -37.624 6.127   3.091   1    107.99 ? 309 LEU A CB  1 -0.345 0.056  0.008  
ATOM   2285  C  CG  . LEU A 1 320 ? -36.489 5.104   2.921   1    98.9   ? 309 LEU A CG  1 -0.334 0.047  0.007  
ATOM   2286  C  CD1 . LEU A 1 320 ? -36.464 4.044   4.008   1    113.61 ? 309 LEU A CD1 1 -0.334 0.037  0.01   
ATOM   2287  C  CD2 . LEU A 1 320 ? -36.484 4.452   1.579   1    103.4  ? 309 LEU A CD2 1 -0.334 0.041  0.004  
ATOM   2288  N  N   . LYS A 1 321 ? -40.339 4.772   4.539   1    120.01 ? 310 LYS A N   1 -0.37  0.044  0.011  
ATOM   2289  C  CA  . LYS A 1 321 ? -41.077 3.616   5.033   1    121.68 ? 310 LYS A CA  1 -0.376 0.033  0.013  
ATOM   2290  C  C   . LYS A 1 321 ? -42.248 3.337   4.117   1    119.32 ? 310 LYS A C   1 -0.387 0.031  0.01   
ATOM   2291  O  O   . LYS A 1 321 ? -42.581 2.177   3.857   1    121.06 ? 310 LYS A O   1 -0.39  0.02   0.01   
ATOM   2292  C  CB  . LYS A 1 321 ? -41.568 3.827   6.472   1    116.69 ? 310 LYS A CB  1 -0.381 0.035  0.016  
ATOM   2293  C  CG  . LYS A 1 321 ? -42.173 2.564   7.13    1    124.68 ? 310 LYS A CG  1 -0.386 0.023  0.018  
ATOM   2294  C  CD  . LYS A 1 321 ? -42.992 2.883   8.406   1    128.15 ? 310 LYS A CD  1 -0.394 0.026  0.021  
ATOM   2295  C  CE  . LYS A 1 321 ? -44.509 2.892   8.135   1    129.67 ? 310 LYS A CE  1 -0.408 0.027  0.02   
ATOM   2296  N  NZ  . LYS A 1 321 ? -45.185 1.576   8.401   1    127.88 ? 310 LYS A NZ  1 -0.414 0.014  0.021  
ATOM   2297  N  N   . GLU A 1 322 ? -42.854 4.392   3.581   1    121.1  ? 311 GLU A N   1 -0.393 0.04   0.009  
ATOM   2298  C  CA  . GLU A 1 322 ? -43.994 4.184   2.715   1    127.61 ? 311 GLU A CA  1 -0.403 0.038  0.007  
ATOM   2299  C  C   . GLU A 1 322 ? -43.578 3.79    1.298   1    130.93 ? 311 GLU A C   1 -0.399 0.035  0.003  
ATOM   2300  O  O   . GLU A 1 322 ? -44.062 2.781   0.768   1    131.63 ? 311 GLU A O   1 -0.404 0.025  0.002  
ATOM   2301  C  CB  . GLU A 1 322 ? -44.9   5.427   2.695   1    127.27 ? 311 GLU A CB  1 -0.411 0.05   0.007  
ATOM   2302  C  CG  . GLU A 1 322 ? -46.14  5.272   1.809   1    137.15 ? 311 GLU A CG  1 -0.423 0.048  0.005  
ATOM   2303  C  CD  . GLU A 1 322 ? -46.972 4.044   2.154   1    143.58 ? 311 GLU A CD  1 -0.43  0.037  0.005  
ATOM   2304  O  OE1 . GLU A 1 322 ? -48.154 4.213   2.531   1    150.63 ? 311 GLU A OE1 1 -0.441 0.039  0.006  
ATOM   2305  O  OE2 . GLU A 1 322 ? -46.456 2.91    2.034   1    146.29 ? 311 GLU A OE2 1 -0.426 0.027  0.005  
ATOM   2306  N  N   . SER A 1 323 ? -42.68  4.564   0.671   1    125.03 ? 312 SER A N   1 -0.391 0.042  0.002  
ATOM   2307  C  CA  . SER A 1 323 ? -42.228 4.239   -0.68   1    123.96 ? 312 SER A CA  1 -0.387 0.039  -0.002 
ATOM   2308  C  C   . SER A 1 323 ? -41.816 2.777   -0.81   1    124.47 ? 312 SER A C   1 -0.383 0.025  -0.002 
ATOM   2309  O  O   . SER A 1 323 ? -42.017 2.179   -1.869  1    136.2  ? 312 SER A O   1 -0.385 0.02   -0.005 
ATOM   2310  C  CB  . SER A 1 323 ? -41.085 5.167   -1.102  1    127.12 ? 312 SER A CB  1 -0.377 0.047  -0.003 
ATOM   2311  O  OG  . SER A 1 323 ? -41.597 6.417   -1.547  1    130.9  ? 312 SER A OG  1 -0.381 0.059  -0.004 
ATOM   2312  N  N   . ILE A 1 324 ? -41.296 2.168   0.257   1    122.7  ? 313 ILE A N   1 -0.378 0.02   0.001  
ATOM   2313  C  CA  . ILE A 1 324 ? -41.008 0.732   0.227   1    127.85 ? 313 ILE A CA  1 -0.376 0.007  0.001  
ATOM   2314  C  C   . ILE A 1 324 ? -42.304 -0.073  0.112   1    134.27 ? 313 ILE A C   1 -0.388 -0.001 0.0    
ATOM   2315  O  O   . ILE A 1 324 ? -42.414 -0.976  -0.729  1    136.83 ? 313 ILE A O   1 -0.389 -0.009 -0.002 
ATOM   2316  C  CB  . ILE A 1 324 ? -40.189 0.303   1.465   1    123.81 ? 313 ILE A CB  1 -0.368 0.003  0.004  
ATOM   2317  C  CG1 . ILE A 1 324 ? -38.68  0.444   1.244   1    116.74 ? 313 ILE A CG1 1 -0.354 0.004  0.003  
ATOM   2318  C  CG2 . ILE A 1 324 ? -40.408 -1.163  1.774   1    120.85 ? 313 ILE A CG2 1 -0.37  -0.011 0.004  
ATOM   2319  C  CD1 . ILE A 1 324 ? -38.236 1.729   0.619   1    119.1  ? 313 ILE A CD1 1 -0.35  0.016  0.002  
ATOM   2320  N  N   . ARG A 1 325 ? -43.301 0.236   0.96    1    131.56 ? 314 ARG A N   1 -0.397 0.002  0.002  
ATOM   2321  C  CA  . ARG A 1 325 ? -44.567 -0.504  0.941   1    132.81 ? 314 ARG A CA  1 -0.408 -0.005 0.002  
ATOM   2322  C  C   . ARG A 1 325 ? -45.282 -0.354  -0.401  1    139.65 ? 314 ARG A C   1 -0.415 -0.003 -0.001 
ATOM   2323  O  O   . ARG A 1 325 ? -45.863 -1.321  -0.911  1    140.93 ? 314 ARG A O   1 -0.42  -0.012 -0.002 
ATOM   2324  C  CB  . ARG A 1 325 ? -45.474 -0.038  2.09    1    136.24 ? 314 ARG A CB  1 -0.417 -0.0   0.005  
ATOM   2325  C  CG  . ARG A 1 325 ? -46.875 -0.704  2.176   1    138.92 ? 314 ARG A CG  1 -0.43  -0.006 0.005  
ATOM   2326  C  CD  . ARG A 1 325 ? -47.884 0.084   3.062   1    134.47 ? 314 ARG A CD  1 -0.439 0.001  0.008  
ATOM   2327  N  NE  . ARG A 1 325 ? -48.444 1.263   2.399   1    143.49 ? 314 ARG A NE  1 -0.444 0.012  0.006  
ATOM   2328  C  CZ  . ARG A 1 325 ? -49.741 1.504   2.224   1    144.15 ? 314 ARG A CZ  1 -0.456 0.014  0.006  
ATOM   2329  N  NH1 . ARG A 1 325 ? -50.669 0.683   2.69    1    141.59 ? 314 ARG A NH1 1 -0.464 0.006  0.007  
ATOM   2330  N  NH2 . ARG A 1 325 ? -50.115 2.605   1.574   1    142.95 ? 314 ARG A NH2 1 -0.459 0.024  0.004  
ATOM   2331  N  N   . GLU A 1 326 ? -45.256 0.848   -0.989  1    138.82 ? 315 GLU A N   1 -0.415 0.008  -0.002 
ATOM   2332  C  CA  . GLU A 1 326 ? -45.889 1.036   -2.293  1    136.95 ? 315 GLU A CA  1 -0.421 0.009  -0.006 
ATOM   2333  C  C   . GLU A 1 326 ? -45.264 0.123   -3.334  1    138.94 ? 315 GLU A C   1 -0.415 0.001  -0.008 
ATOM   2334  O  O   . GLU A 1 326 ? -45.973 -0.568  -4.073  1    141.77 ? 315 GLU A O   1 -0.421 -0.005 -0.01  
ATOM   2335  C  CB  . GLU A 1 326 ? -45.79  2.495   -2.744  1    138.3  ? 315 GLU A CB  1 -0.42  0.023  -0.007 
ATOM   2336  C  CG  . GLU A 1 326 ? -46.508 3.504   -1.849  1    140.46 ? 315 GLU A CG  1 -0.426 0.032  -0.005 
ATOM   2337  C  CD  . GLU A 1 326 ? -47.828 2.978   -1.276  1    147.98 ? 315 GLU A CD  1 -0.438 0.027  -0.003 
ATOM   2338  O  OE1 . GLU A 1 326 ? -47.785 2.215   -0.281  1    148.03 ? 315 GLU A OE1 1 -0.438 0.02   -0.001 
ATOM   2339  O  OE2 . GLU A 1 326 ? -48.91  3.324   -1.813  1    147.2  ? 315 GLU A OE2 1 -0.448 0.03   -0.005 
ATOM   2340  N  N   . ALA A 1 327 ? -43.932 0.09    -3.391  1    137.7  ? 316 ALA A N   1 -0.403 0.001  -0.008 
ATOM   2341  C  CA  . ALA A 1 327 ? -43.243 -0.722  -4.382  1    137.09 ? 316 ALA A CA  1 -0.396 -0.007 -0.011 
ATOM   2342  C  C   . ALA A 1 327 ? -43.266 -2.222  -4.073  1    138.56 ? 316 ALA A C   1 -0.396 -0.02  -0.01  
ATOM   2343  O  O   . ALA A 1 327 ? -43.107 -3.02   -5.007  1    138.14 ? 316 ALA A O   1 -0.395 -0.028 -0.013 
ATOM   2344  C  CB  . ALA A 1 327 ? -41.802 -0.228  -4.538  1    130.28 ? 316 ALA A CB  1 -0.383 -0.002 -0.011 
ATOM   2345  N  N   . LYS A 1 328 ? -43.453 -2.629  -2.805  1    141.03 ? 317 LYS A N   1 -0.398 -0.024 -0.007 
ATOM   2346  C  CA  . LYS A 1 328 ? -43.644 -4.047  -2.485  1    145.76 ? 317 LYS A CA  1 -0.4   -0.037 -0.006 
ATOM   2347  C  C   . LYS A 1 328 ? -44.927 -4.524  -3.156  1    147.73 ? 317 LYS A C   1 -0.412 -0.041 -0.008 
ATOM   2348  O  O   . LYS A 1 328 ? -44.891 -5.265  -4.137  1    146.3  ? 317 LYS A O   1 -0.411 -0.048 -0.01  
ATOM   2349  C  CB  . LYS A 1 328 ? -43.685 -4.295  -0.964  1    145.14 ? 317 LYS A CB  1 -0.4   -0.039 -0.002 
ATOM   2350  C  CG  . LYS A 1 328 ? -43.852 -5.795  -0.566  1    153.45 ? 317 LYS A CG  1 -0.402 -0.053 -0.001 
ATOM   2351  C  CD  . LYS A 1 328 ? -45.353 -6.197  -0.497  1    153.66 ? 317 LYS A CD  1 -0.416 -0.057 -0.001 
ATOM   2352  C  CE  . LYS A 1 328 ? -45.633 -7.643  -0.182  1    153.75 ? 317 LYS A CE  1 -0.418 -0.07  -0.0   
ATOM   2353  N  NZ  . LYS A 1 328 ? -47.052 -7.859  -0.627  1    147.47 ? 317 LYS A NZ  1 -0.431 -0.072 -0.002 
ATOM   2354  N  N   . ALA A 1 329 ? -46.074 -4.035  -2.671  1    147.07 ? 318 ALA A N   1 -0.422 -0.037 -0.007 
ATOM   2355  C  CA  . ALA A 1 329 ? -47.359 -4.562  -3.113  1    147.29 ? 318 ALA A CA  1 -0.434 -0.042 -0.008 
ATOM   2356  C  C   . ALA A 1 329 ? -47.665 -4.275  -4.588  1    145.26 ? 318 ALA A C   1 -0.437 -0.039 -0.011 
ATOM   2357  O  O   . ALA A 1 329 ? -48.635 -4.835  -5.118  1    143.31 ? 318 ALA A O   1 -0.446 -0.044 -0.013 
ATOM   2358  C  CB  . ALA A 1 329 ? -48.45  -4.002  -2.201  1    147.01 ? 318 ALA A CB  1 -0.444 -0.037 -0.005 
ATOM   2359  N  N   . LYS A 1 330 ? -46.884 -3.408  -5.247  1    146.21 ? 319 LYS A N   1 -0.43  -0.031 -0.013 
ATOM   2360  C  CA  . LYS A 1 330 ? -46.896 -3.218  -6.697  1    141.65 ? 319 LYS A CA  1 -0.43  -0.029 -0.017 
ATOM   2361  C  C   . LYS A 1 330 ? -45.834 -4.049  -7.417  1    142.48 ? 319 LYS A C   1 -0.42  -0.037 -0.019 
ATOM   2362  O  O   . LYS A 1 330 ? -45.896 -4.182  -8.649  1    144.77 ? 319 LYS A O   1 -0.421 -0.038 -0.022 
ATOM   2363  C  CB  . LYS A 1 330 ? -46.707 -1.73   -7.036  1    138.63 ? 319 LYS A CB  1 -0.428 -0.016 -0.018 
ATOM   2364  C  CG  . LYS A 1 330 ? -47.929 -0.893  -6.727  1    139.46 ? 319 LYS A CG  1 -0.439 -0.008 -0.017 
ATOM   2365  C  CD  . LYS A 1 330 ? -49.067 -1.322  -7.632  1    147.45 ? 319 LYS A CD  1 -0.45  -0.012 -0.019 
ATOM   2366  C  CE  . LYS A 1 330 ? -50.392 -0.702  -7.215  1    154.88 ? 319 LYS A CE  1 -0.462 -0.006 -0.018 
ATOM   2367  N  NZ  . LYS A 1 330 ? -51.509 -1.112  -8.128  1    151.19 ? 319 LYS A NZ  1 -0.472 -0.01  -0.02  
ATOM   2368  N  N   . GLY A 1 331 ? -44.861 -4.603  -6.689  1    138.3  ? 320 GLY A N   1 -0.411 -0.042 -0.017 
ATOM   2369  C  CA  . GLY A 1 331 ? -43.869 -5.494  -7.25   1    134.53 ? 320 GLY A CA  1 -0.402 -0.05  -0.018 
ATOM   2370  C  C   . GLY A 1 331 ? -42.581 -4.846  -7.733  1    132.91 ? 320 GLY A C   1 -0.39  -0.044 -0.019 
ATOM   2371  O  O   . GLY A 1 331 ? -41.554 -5.53   -7.797  1    131.78 ? 320 GLY A O   1 -0.381 -0.051 -0.019 
ATOM   2372  N  N   . GLN A 1 332 ? -42.601 -3.552  -8.073  1    126.21 ? 321 GLN A N   1 -0.39  -0.033 -0.02  
ATOM   2373  C  CA  . GLN A 1 332 ? -41.421 -2.89   -8.62   1    120.35 ? 321 GLN A CA  1 -0.38  -0.026 -0.022 
ATOM   2374  C  C   . GLN A 1 332 ? -40.303 -2.801  -7.58   1    125.65 ? 321 GLN A C   1 -0.369 -0.026 -0.019 
ATOM   2375  O  O   . GLN A 1 332 ? -40.5   -3.043  -6.383  1    128.54 ? 321 GLN A O   1 -0.371 -0.028 -0.016 
ATOM   2376  C  CB  . GLN A 1 332 ? -41.772 -1.496  -9.127  1    119.47 ? 321 GLN A CB  1 -0.383 -0.014 -0.023 
ATOM   2377  C  CG  . GLN A 1 332 ? -42.322 -0.569  -8.081  1    125.73 ? 321 GLN A CG  1 -0.388 -0.005 -0.02  
ATOM   2378  C  CD  . GLN A 1 332 ? -43.794 -0.248  -8.301  1    134.76 ? 321 GLN A CD  1 -0.401 -0.002 -0.021 
ATOM   2379  O  OE1 . GLN A 1 332 ? -44.438 -0.813  -9.186  1    132.75 ? 321 GLN A OE1 1 -0.407 -0.007 -0.023 
ATOM   2380  N  NE2 . GLN A 1 332 ? -44.332 0.67    -7.494  1    137.51 ? 321 GLN A NE2 1 -0.406 0.006  -0.019 
ATOM   2381  N  N   . LYS A 1 333 ? -39.105 -2.464  -8.056  1    122.36 ? 322 LYS A N   1 -0.358 -0.023 -0.02  
ATOM   2382  C  CA  . LYS A 1 333 ? -37.943 -2.293  -7.193  1    118.33 ? 322 LYS A CA  1 -0.348 -0.021 -0.018 
ATOM   2383  C  C   . LYS A 1 333 ? -37.734 -0.812  -6.878  1    118.01 ? 322 LYS A C   1 -0.346 -0.007 -0.017 
ATOM   2384  O  O   . LYS A 1 333 ? -38.402 0.068   -7.435  1    116.29 ? 322 LYS A O   1 -0.352 0.001  -0.019 
ATOM   2385  C  CB  . LYS A 1 333 ? -36.676 -2.883  -7.831  1    117.74 ? 322 LYS A CB  1 -0.336 -0.026 -0.02  
ATOM   2386  C  CG  . LYS A 1 333 ? -36.746 -4.359  -8.203  1    118.47 ? 322 LYS A CG  1 -0.337 -0.04  -0.02  
ATOM   2387  C  CD  . LYS A 1 333 ? -37.393 -5.195  -7.12   1    111.81 ? 322 LYS A CD  1 -0.343 -0.048 -0.018 
ATOM   2388  C  CE  . LYS A 1 333 ? -36.854 -6.612  -7.137  1    111.96 ? 322 LYS A CE  1 -0.338 -0.061 -0.018 
ATOM   2389  N  NZ  . LYS A 1 333 ? -35.372 -6.636  -6.909  1    116.32 ? 322 LYS A NZ  1 -0.324 -0.061 -0.017 
ATOM   2390  N  N   . ILE A 1 334 ? -36.791 -0.545  -5.968  1    118.6  ? 323 ILE A N   1 -0.337 -0.005 -0.015 
ATOM   2391  C  CA  . ILE A 1 334 ? -36.494 0.81    -5.507  1    114    ? 323 ILE A CA  1 -0.334 0.007  -0.014 
ATOM   2392  C  C   . ILE A 1 334 ? -34.988 1.024   -5.492  1    110.03 ? 323 ILE A C   1 -0.321 0.009  -0.014 
ATOM   2393  O  O   . ILE A 1 334 ? -34.241 0.179   -4.992  1    112.05 ? 323 ILE A O   1 -0.314 0.002  -0.012 
ATOM   2394  C  CB  . ILE A 1 334 ? -37.082 1.083   -4.11   1    114.34 ? 323 ILE A CB  1 -0.34  0.01   -0.01  
ATOM   2395  C  CG1 . ILE A 1 334 ? -38.594 1.263   -4.215  1    115.84 ? 323 ILE A CG1 1 -0.354 0.012  -0.011 
ATOM   2396  C  CG2 . ILE A 1 334 ? -36.422 2.305   -3.471  1    111.43 ? 323 ILE A CG2 1 -0.334 0.021  -0.009 
ATOM   2397  C  CD1 . ILE A 1 334 ? -39.196 2.03    -3.076  1    122.55 ? 323 ILE A CD1 1 -0.359 0.019  -0.008 
ATOM   2398  N  N   . ALA A 1 335 ? -34.544 2.148   -6.041  1    104.41 ? 324 ALA A N   1 -0.317 0.02   -0.015 
ATOM   2399  C  CA  . ALA A 1 335 ? -33.172 2.607   -5.9    1    105.64 ? 324 ALA A CA  1 -0.304 0.024  -0.015 
ATOM   2400  C  C   . ALA A 1 335 ? -33.181 3.852   -5.027  1    110.91 ? 324 ALA A C   1 -0.304 0.035  -0.013 
ATOM   2401  O  O   . ALA A 1 335 ? -33.968 4.774   -5.27   1    108.65 ? 324 ALA A O   1 -0.311 0.044  -0.013 
ATOM   2402  C  CB  . ALA A 1 335 ? -32.529 2.905   -7.252  1    103.9  ? 324 ALA A CB  1 -0.298 0.027  -0.018 
ATOM   2403  N  N   . LEU A 1 336 ? -32.303 3.868   -4.021  1    113.45 ? 325 LEU A N   1 -0.296 0.035  -0.01  
ATOM   2404  C  CA  . LEU A 1 336 ? -32.337 4.807   -2.903  1    100.34 ? 325 LEU A CA  1 -0.296 0.044  -0.007 
ATOM   2405  C  C   . LEU A 1 336 ? -31.068 5.65    -2.947  1    99.42  ? 325 LEU A C   1 -0.285 0.052  -0.007 
ATOM   2406  O  O   . LEU A 1 336 ? -29.959 5.105   -2.892  1    101.74 ? 325 LEU A O   1 -0.275 0.047  -0.007 
ATOM   2407  C  CB  . LEU A 1 336 ? -32.449 4.033   -1.588  1    96.61  ? 325 LEU A CB  1 -0.297 0.037  -0.004 
ATOM   2408  C  CG  . LEU A 1 336 ? -32.443 4.746   -0.231  1    108.25 ? 325 LEU A CG  1 -0.297 0.043  -0.001 
ATOM   2409  C  CD1 . LEU A 1 336 ? -31.019 4.982   0.3     1    104.46 ? 325 LEU A CD1 1 -0.284 0.046  0.001  
ATOM   2410  C  CD2 . LEU A 1 336 ? -33.25  6.049   -0.278  1    104.38 ? 325 LEU A CD2 1 -0.305 0.055  -0.001 
ATOM   2411  N  N   . TYR A 1 337 ? -31.223 6.969   -3.063  1    95.27  ? 326 TYR A N   1 -0.286 0.064  -0.008 
ATOM   2412  C  CA  . TYR A 1 337 ? -30.089 7.86    -3.302  1    97.26  ? 326 TYR A CA  1 -0.276 0.072  -0.008 
ATOM   2413  C  C   . TYR A 1 337 ? -29.994 8.87    -2.174  1    101.8  ? 326 TYR A C   1 -0.275 0.081  -0.005 
ATOM   2414  O  O   . TYR A 1 337 ? -30.927 9.65    -1.951  1    100.39 ? 326 TYR A O   1 -0.283 0.088  -0.005 
ATOM   2415  C  CB  . TYR A 1 337 ? -30.204 8.577   -4.645  1    99.72  ? 326 TYR A CB  1 -0.277 0.079  -0.012 
ATOM   2416  C  CG  . TYR A 1 337 ? -30.04  7.643   -5.824  1    104.86 ? 326 TYR A CG  1 -0.275 0.07   -0.015 
ATOM   2417  C  CD1 . TYR A 1 337 ? -31.058 6.761   -6.186  1    99.76  ? 326 TYR A CD1 1 -0.285 0.062  -0.015 
ATOM   2418  C  CD2 . TYR A 1 337 ? -28.86  7.636   -6.571  1    105.36 ? 326 TYR A CD2 1 -0.264 0.07   -0.016 
ATOM   2419  C  CE1 . TYR A 1 337 ? -30.905 5.901   -7.243  1    106.81 ? 326 TYR A CE1 1 -0.283 0.054  -0.018 
ATOM   2420  C  CE2 . TYR A 1 337 ? -28.697 6.782   -7.646  1    100.95 ? 326 TYR A CE2 1 -0.263 0.062  -0.019 
ATOM   2421  C  CZ  . TYR A 1 337 ? -29.723 5.912   -7.979  1    107.72 ? 326 TYR A CZ  1 -0.272 0.054  -0.02  
ATOM   2422  O  OH  . TYR A 1 337 ? -29.579 5.046   -9.044  1    104.43 ? 326 TYR A OH  1 -0.271 0.046  -0.023 
ATOM   2423  N  N   . LEU A 1 338 ? -28.859 8.852   -1.477  1    101.31 ? 327 LEU A N   1 -0.264 0.081  -0.004 
ATOM   2424  C  CA  . LEU A 1 338 ? -28.574 9.714   -0.339  1    97.05  ? 327 LEU A CA  1 -0.262 0.089  -0.001 
ATOM   2425  C  C   . LEU A 1 338 ? -27.474 10.689  -0.732  1    95.99  ? 327 LEU A C   1 -0.252 0.098  -0.002 
ATOM   2426  O  O   . LEU A 1 338 ? -26.279 10.375  -0.599  1    93.42  ? 327 LEU A O   1 -0.241 0.095  -0.001 
ATOM   2427  C  CB  . LEU A 1 338 ? -28.165 8.872   0.87    1    94.6   ? 327 LEU A CB  1 -0.258 0.081  0.002  
ATOM   2428  C  CG  . LEU A 1 338 ? -29.278 7.902   1.26    1    94.49  ? 327 LEU A CG  1 -0.268 0.072  0.003  
ATOM   2429  C  CD1 . LEU A 1 338 ? -28.899 7.109   2.495   1    95.7   ? 327 LEU A CD1 1 -0.265 0.065  0.006  
ATOM   2430  C  CD2 . LEU A 1 338 ? -30.612 8.648   1.442   1    94.12  ? 327 LEU A CD2 1 -0.281 0.079  0.004  
ATOM   2431  N  N   . PRO A 1 339 ? -27.823 11.867  -1.281  1    94.51  ? 328 PRO A N   1 -0.255 0.109  -0.003 
ATOM   2432  C  CA  . PRO A 1 339 ? -26.826 12.93   -1.457  1    96.43  ? 328 PRO A CA  1 -0.246 0.118  -0.004 
ATOM   2433  C  C   . PRO A 1 339 ? -26.75  13.738  -0.18   1    96.36  ? 328 PRO A C   1 -0.245 0.126  -0.0   
ATOM   2434  O  O   . PRO A 1 339 ? -27.488 14.714  0.027   1    92.79  ? 328 PRO A O   1 -0.252 0.135  0.0    
ATOM   2435  C  CB  . PRO A 1 339 ? -27.361 13.738  -2.645  1    96.69  ? 328 PRO A CB  1 -0.251 0.126  -0.007 
ATOM   2436  C  CG  . PRO A 1 339 ? -28.85  13.545  -2.579  1    102.55 ? 328 PRO A CG  1 -0.264 0.124  -0.006 
ATOM   2437  C  CD  . PRO A 1 339 ? -29.134 12.243  -1.834  1    100.4  ? 328 PRO A CD  1 -0.267 0.112  -0.005 
ATOM   2438  N  N   . THR A 1 340 ? -25.84  13.292  0.684   1    97.73  ? 329 THR A N   1 -0.237 0.122  0.002  
ATOM   2439  C  CA  . THR A 1 340 ? -25.776 13.696  2.078   1    98.41  ? 329 THR A CA  1 -0.236 0.126  0.005  
ATOM   2440  C  C   . THR A 1 340 ? -24.665 14.707  2.288   1    94.55  ? 329 THR A C   1 -0.226 0.135  0.006  
ATOM   2441  O  O   . THR A 1 340 ? -23.53  14.51   1.831   1    88.81  ? 329 THR A O   1 -0.216 0.133  0.005  
ATOM   2442  C  CB  . THR A 1 340 ? -25.546 12.484  2.983   1    96.79  ? 329 THR A CB  1 -0.234 0.114  0.007  
ATOM   2443  O  OG1 . THR A 1 340 ? -26.229 11.358  2.425   1    101.59 ? 329 THR A OG1 1 -0.24  0.104  0.006  
ATOM   2444  C  CG2 . THR A 1 340 ? -26.089 12.759  4.374   1    101.5  ? 329 THR A CG2 1 -0.239 0.117  0.011  
ATOM   2445  N  N   . GLY A 1 341 ? -25.019 15.798  2.959   1    95.93  ? 330 GLY A N   1 -0.229 0.145  0.007  
ATOM   2446  C  CA  . GLY A 1 341 ? -24.043 16.727  3.49    1    94.52  ? 330 GLY A CA  1 -0.22  0.153  0.009  
ATOM   2447  C  C   . GLY A 1 341 ? -24.118 16.731  5.005   1    99.16  ? 330 GLY A C   1 -0.221 0.153  0.012  
ATOM   2448  O  O   . GLY A 1 341 ? -25.149 16.394  5.6     1    93     ? 330 GLY A O   1 -0.23  0.15   0.014  
ATOM   2449  N  N   . TRP A 1 342 ? -23.005 17.102  5.622   1    99.21  ? 331 TRP A N   1 -0.211 0.157  0.014  
ATOM   2450  C  CA  . TRP A 1 342 ? -22.925 17.224  7.059   1    88.81  ? 331 TRP A CA  1 -0.21  0.158  0.018  
ATOM   2451  C  C   . TRP A 1 342 ? -22.948 18.667  7.533   1    94.51  ? 331 TRP A C   1 -0.21  0.171  0.019  
ATOM   2452  O  O   . TRP A 1 342 ? -23.028 18.895  8.744   1    104.86 ? 331 TRP A O   1 -0.211 0.173  0.022  
ATOM   2453  C  CB  . TRP A 1 342 ? -21.673 16.509  7.57    1    85.36  ? 331 TRP A CB  1 -0.199 0.151  0.019  
ATOM   2454  C  CG  . TRP A 1 342 ? -21.88  15.018  7.605   1    92.49  ? 331 TRP A CG  1 -0.201 0.138  0.019  
ATOM   2455  C  CD1 . TRP A 1 342 ? -23.027 14.362  7.969   1    96.6   ? 331 TRP A CD1 1 -0.211 0.132  0.02   
ATOM   2456  C  CD2 . TRP A 1 342 ? -20.939 14      7.242   1    87.98  ? 331 TRP A CD2 1 -0.192 0.128  0.018  
ATOM   2457  N  NE1 . TRP A 1 342 ? -22.851 13.001  7.875   1    91.99  ? 331 TRP A NE1 1 -0.209 0.119  0.02   
ATOM   2458  C  CE2 . TRP A 1 342 ? -21.578 12.752  7.432   1    90.04  ? 331 TRP A CE2 1 -0.198 0.117  0.019  
ATOM   2459  C  CE3 . TRP A 1 342 ? -19.621 14.017  6.792   1    83.02  ? 331 TRP A CE3 1 -0.18  0.128  0.017  
ATOM   2460  C  CZ2 . TRP A 1 342 ? -20.944 11.544  7.178   1    86.04  ? 331 TRP A CZ2 1 -0.192 0.106  0.018  
ATOM   2461  C  CZ3 . TRP A 1 342 ? -18.997 12.817  6.549   1    84.47  ? 331 TRP A CZ3 1 -0.174 0.117  0.016  
ATOM   2462  C  CH2 . TRP A 1 342 ? -19.657 11.599  6.744   1    81.93  ? 331 TRP A CH2 1 -0.18  0.106  0.017  
ATOM   2463  N  N   . ASP A 1 343 ? -22.92  19.646  6.63    1    92.12  ? 332 ASP A N   1 -0.21  0.18   0.017  
ATOM   2464  C  CA  . ASP A 1 343 ? -23.053 21.017  7.101   1    95.02  ? 332 ASP A CA  1 -0.211 0.193  0.018  
ATOM   2465  C  C   . ASP A 1 343 ? -24.399 21.254  7.763   1    96.81  ? 332 ASP A C   1 -0.224 0.195  0.019  
ATOM   2466  O  O   . ASP A 1 343 ? -24.57  22.284  8.425   1    101.85 ? 332 ASP A O   1 -0.225 0.204  0.021  
ATOM   2467  C  CB  . ASP A 1 343 ? -22.828 22.032  5.972   1    100.46 ? 332 ASP A CB  1 -0.209 0.202  0.015  
ATOM   2468  C  CG  . ASP A 1 343 ? -23.538 21.653  4.679   1    105.85 ? 332 ASP A CG  1 -0.216 0.198  0.012  
ATOM   2469  O  OD1 . ASP A 1 343 ? -24.367 20.714  4.71    1    100.53 ? 332 ASP A OD1 1 -0.223 0.19   0.012  
ATOM   2470  O  OD2 . ASP A 1 343 ? -23.277 22.311  3.636   1    108.54 ? 332 ASP A OD2 1 -0.213 0.204  0.009  
ATOM   2471  N  N   . SER A 1 344 ? -25.336 20.318  7.636   1    91.8   ? 333 SER A N   1 -0.232 0.186  0.019  
ATOM   2472  C  CA  . SER A 1 344 ? -26.591 20.384  8.37    1    95.01  ? 333 SER A CA  1 -0.244 0.187  0.021  
ATOM   2473  C  C   . SER A 1 344 ? -26.446 19.998  9.837   1    102.9  ? 333 SER A C   1 -0.242 0.183  0.025  
ATOM   2474  O  O   . SER A 1 344 ? -27.451 19.976  10.556  1    99.14  ? 333 SER A O   1 -0.252 0.183  0.026  
ATOM   2475  C  CB  . SER A 1 344 ? -27.635 19.49   7.715   1    92.44  ? 333 SER A CB  1 -0.253 0.179  0.019  
ATOM   2476  O  OG  . SER A 1 344 ? -27.02  18.313  7.238   1    96.56  ? 333 SER A OG  1 -0.248 0.168  0.018  
ATOM   2477  N  N   . HIS A 1 345 ? -25.239 19.689  10.3    1    102.52 ? 334 HIS A N   1 -0.231 0.18   0.026  
ATOM   2478  C  CA  . HIS A 1 345 ? -25.033 19.402  11.712  1    104.03 ? 334 HIS A CA  1 -0.229 0.178  0.029  
ATOM   2479  C  C   . HIS A 1 345 ? -25.044 20.69   12.531  1    106.27 ? 334 HIS A C   1 -0.23  0.19   0.031  
ATOM   2480  O  O   . HIS A 1 345 ? -24.724 21.774  12.024  1    104.86 ? 334 HIS A O   1 -0.227 0.2    0.03   
ATOM   2481  C  CB  . HIS A 1 345 ? -23.713 18.669  11.923  1    101.19 ? 334 HIS A CB  1 -0.217 0.171  0.03   
ATOM   2482  C  CG  . HIS A 1 345 ? -23.67  17.869  13.182  1    105.54 ? 334 HIS A CG  1 -0.217 0.164  0.033  
ATOM   2483  N  ND1 . HIS A 1 345 ? -23.339 18.42   14.402  1    104.64 ? 334 HIS A ND1 1 -0.214 0.169  0.036  
ATOM   2484  C  CD2 . HIS A 1 345 ? -23.925 16.56   13.415  1    104.65 ? 334 HIS A CD2 1 -0.219 0.152  0.033  
ATOM   2485  C  CE1 . HIS A 1 345 ? -23.371 17.48   15.329  1    103.39 ? 334 HIS A CE1 1 -0.214 0.16   0.038  
ATOM   2486  N  NE2 . HIS A 1 345 ? -23.73  16.344  14.761  1    103.28 ? 334 HIS A NE2 1 -0.217 0.15   0.037  
ATOM   2487  N  N   . GLU A 1 346 ? -25.427 20.569  13.813  1    103.55 ? 335 GLU A N   1 -0.233 0.188  0.034  
ATOM   2488  C  CA  . GLU A 1 346 ? -25.385 21.739  14.684  1    102.56 ? 335 GLU A CA  1 -0.233 0.199  0.037  
ATOM   2489  C  C   . GLU A 1 346 ? -23.949 22.187  14.91   1    103.31 ? 335 GLU A C   1 -0.219 0.203  0.037  
ATOM   2490  O  O   . GLU A 1 346 ? -23.691 23.379  15.128  1    101.51 ? 335 GLU A O   1 -0.217 0.214  0.038  
ATOM   2491  C  CB  . GLU A 1 346 ? -26.082 21.429  16.009  1    109.77 ? 335 GLU A CB  1 -0.239 0.196  0.04   
ATOM   2492  C  CG  . GLU A 1 346 ? -25.431 20.281  16.795  1    113.1  ? 335 GLU A CG  1 -0.233 0.186  0.042  
ATOM   2493  C  CD  . GLU A 1 346 ? -26.186 19.876  18.058  1    114.09 ? 335 GLU A CD  1 -0.24  0.182  0.045  
ATOM   2494  O  OE1 . GLU A 1 346 ? -27.288 20.418  18.326  1    120.56 ? 335 GLU A OE1 1 -0.25  0.187  0.046  
ATOM   2495  O  OE2 . GLU A 1 346 ? -25.662 18.998  18.781  1    114.01 ? 335 GLU A OE2 1 -0.235 0.174  0.047  
ATOM   2496  N  N   . ASP A 1 347 ? -23.008 21.248  14.814  1    101.93 ? 336 ASP A N   1 -0.211 0.195  0.037  
ATOM   2497  C  CA  . ASP A 1 347 ? -21.594 21.464  15.062  1    103.2  ? 336 ASP A CA  1 -0.198 0.197  0.038  
ATOM   2498  C  C   . ASP A 1 347 ? -20.837 21.928  13.817  1    108.1  ? 336 ASP A C   1 -0.191 0.201  0.034  
ATOM   2499  O  O   . ASP A 1 347 ? -19.606 21.798  13.776  1    110.55 ? 336 ASP A O   1 -0.18  0.2    0.034  
ATOM   2500  C  CB  . ASP A 1 347 ? -20.958 20.166  15.584  1    105.81 ? 336 ASP A CB  1 -0.192 0.185  0.039  
ATOM   2501  C  CG  . ASP A 1 347 ? -21.168 19.938  17.09   1    112.05 ? 336 ASP A CG  1 -0.194 0.183  0.043  
ATOM   2502  O  OD1 . ASP A 1 347 ? -20.181 19.527  17.744  1    113.34 ? 336 ASP A OD1 1 -0.185 0.179  0.044  
ATOM   2503  O  OD2 . ASP A 1 347 ? -22.285 20.144  17.626  1    111.83 ? 336 ASP A OD2 1 -0.204 0.185  0.044  
ATOM   2504  N  N   . GLU A 1 348 ? -21.536 22.413  12.788  1    108.02 ? 337 GLU A N   1 -0.197 0.205  0.032  
ATOM   2505  C  CA  . GLU A 1 348 ? -20.889 22.946  11.588  1    105.73 ? 337 GLU A CA  1 -0.191 0.21   0.029  
ATOM   2506  C  C   . GLU A 1 348 ? -20.534 24.41   11.816  1    101.25 ? 337 GLU A C   1 -0.188 0.224  0.03   
ATOM   2507  O  O   . GLU A 1 348 ? -21.357 25.185  12.307  1    102.08 ? 337 GLU A O   1 -0.196 0.231  0.031  
ATOM   2508  C  CB  . GLU A 1 348 ? -21.788 22.806  10.351  1    106.24 ? 337 GLU A CB  1 -0.2   0.209  0.026  
ATOM   2509  C  CG  . GLU A 1 348 ? -21.286 23.527  9.096   1    99.56  ? 337 GLU A CG  1 -0.195 0.216  0.023  
ATOM   2510  C  CD  . GLU A 1 348 ? -19.998 22.928  8.555   1    100.84 ? 337 GLU A CD  1 -0.183 0.21   0.021  
ATOM   2511  O  OE1 . GLU A 1 348 ? -20.071 21.891  7.861   1    105.15 ? 337 GLU A OE1 1 -0.184 0.201  0.02   
ATOM   2512  O  OE2 . GLU A 1 348 ? -18.91  23.483  8.822   1    99.32  ? 337 GLU A OE2 1 -0.173 0.215  0.022  
ATOM   2513  N  N   . THR A 1 349 ? -19.315 24.782  11.458  1    102.29 ? 338 THR A N   1 -0.177 0.227  0.029  
ATOM   2514  C  CA  . THR A 1 349 ? -18.855 26.153  11.584  1    101.35 ? 338 THR A CA  1 -0.173 0.24   0.029  
ATOM   2515  C  C   . THR A 1 349 ? -18.74  26.865  10.241  1    111.81 ? 338 THR A C   1 -0.172 0.246  0.026  
ATOM   2516  O  O   . THR A 1 349 ? -18.349 28.036  10.216  1    116.89 ? 338 THR A O   1 -0.168 0.257  0.026  
ATOM   2517  C  CB  . THR A 1 349 ? -17.511 26.162  12.324  1    101.24 ? 338 THR A CB  1 -0.16  0.24   0.031  
ATOM   2518  O  OG1 . THR A 1 349 ? -16.42  26.21   11.395  1    108.73 ? 338 THR A OG1 1 -0.15  0.24   0.028  
ATOM   2519  C  CG2 . THR A 1 349 ? -17.394 24.888  13.154  1    98.31  ? 338 THR A CG2 1 -0.159 0.228  0.033  
ATOM   2520  N  N   . ALA A 1 350 ? -19.084 26.195  9.133   1    106.28 ? 339 ALA A N   1 -0.175 0.24   0.023  
ATOM   2521  C  CA  . ALA A 1 350 ? -18.982 26.79   7.804   1    109.16 ? 339 ALA A CA  1 -0.174 0.246  0.019  
ATOM   2522  C  C   . ALA A 1 350 ? -20.064 27.834  7.565   1    109.63 ? 339 ALA A C   1 -0.184 0.255  0.019  
ATOM   2523  O  O   . ALA A 1 350 ? -21.229 27.648  7.926   1    108.52 ? 339 ALA A O   1 -0.195 0.253  0.02   
ATOM   2524  C  CB  . ALA A 1 350 ? -19.085 25.716  6.72    1    116.37 ? 339 ALA A CB  1 -0.175 0.236  0.017  
ATOM   2525  N  N   . TYR A 1 351 ? -19.667 28.924  6.905   1    112.29 ? 340 TYR A N   1 -0.18  0.265  0.017  
ATOM   2526  C  CA  . TYR A 1 351 ? -20.574 30.042  6.662   1    114.97 ? 340 TYR A CA  1 -0.189 0.275  0.017  
ATOM   2527  C  C   . TYR A 1 351 ? -21.844 29.592  5.939   1    114.01 ? 340 TYR A C   1 -0.2   0.271  0.015  
ATOM   2528  O  O   . TYR A 1 351 ? -22.95  30.043  6.267   1    110.79 ? 340 TYR A O   1 -0.21  0.275  0.016  
ATOM   2529  C  CB  . TYR A 1 351 ? -19.82  31.125  5.87    1    107.9  ? 340 TYR A CB  1 -0.182 0.285  0.015  
ATOM   2530  C  CG  . TYR A 1 351 ? -20.586 32.417  5.628   1    120.42 ? 340 TYR A CG  1 -0.189 0.297  0.014  
ATOM   2531  C  CD1 . TYR A 1 351 ? -20.103 33.65   6.07    1    127.06 ? 340 TYR A CD1 1 -0.184 0.308  0.015  
ATOM   2532  C  CD2 . TYR A 1 351 ? -21.794 32.404  4.939   1    124.11 ? 340 TYR A CD2 1 -0.2   0.297  0.012  
ATOM   2533  C  CE1 . TYR A 1 351 ? -20.83  34.835  5.835   1    129.81 ? 340 TYR A CE1 1 -0.191 0.319  0.015  
ATOM   2534  C  CE2 . TYR A 1 351 ? -22.516 33.551  4.71    1    129.5  ? 340 TYR A CE2 1 -0.206 0.307  0.012  
ATOM   2535  C  CZ  . TYR A 1 351 ? -22.045 34.764  5.144   1    133.42 ? 340 TYR A CZ  1 -0.202 0.319  0.013  
ATOM   2536  O  OH  . TYR A 1 351 ? -22.822 35.869  4.866   1    134.57 ? 340 TYR A OH  1 -0.209 0.329  0.012  
ATOM   2537  N  N   . CYS A 1 352 ? -21.716 28.682  4.973   1    117.48 ? 341 CYS A N   1 -0.199 0.263  0.012  
ATOM   2538  C  CA  . CYS A 1 352 ? -22.871 28.318  4.159   1    115.1  ? 341 CYS A CA  1 -0.21  0.26   0.01   
ATOM   2539  C  C   . CYS A 1 352 ? -23.888 27.456  4.911   1    114.01 ? 341 CYS A C   1 -0.219 0.252  0.012  
ATOM   2540  O  O   . CYS A 1 352 ? -24.97  27.199  4.378   1    111.58 ? 341 CYS A O   1 -0.229 0.249  0.011  
ATOM   2541  C  CB  . CYS A 1 352 ? -22.406 27.621  2.871   1    119.63 ? 341 CYS A CB  1 -0.205 0.253  0.007  
ATOM   2542  S  SG  . CYS A 1 352 ? -21.452 26.066  3.037   1    137.05 ? 341 CYS A SG  1 -0.197 0.239  0.008  
ATOM   2543  N  N   . GLY A 1 353 ? -23.589 27.032  6.136   1    114.48 ? 342 GLY A N   1 -0.216 0.248  0.015  
ATOM   2544  C  CA  . GLY A 1 353 ? -24.571 26.304  6.916   1    115.67 ? 342 GLY A CA  1 -0.225 0.241  0.017  
ATOM   2545  C  C   . GLY A 1 353 ? -25.062 27.004  8.177   1    113.34 ? 342 GLY A C   1 -0.23  0.247  0.02   
ATOM   2546  O  O   . GLY A 1 353 ? -26.02  26.545  8.816   1    104.36 ? 342 GLY A O   1 -0.238 0.243  0.022  
ATOM   2547  N  N   . LYS A 1 354 ? -24.437 28.129  8.547   1    113.29 ? 343 LYS A N   1 -0.224 0.258  0.021  
ATOM   2548  C  CA  . LYS A 1 354 ? -24.643 28.711  9.865   1    115.57 ? 343 LYS A CA  1 -0.226 0.263  0.025  
ATOM   2549  C  C   . LYS A 1 354 ? -24.869 30.218  9.901   1    116.41 ? 343 LYS A C   1 -0.228 0.277  0.025  
ATOM   2550  O  O   . LYS A 1 354 ? -25.371 30.705  10.919  1    125.02 ? 343 LYS A O   1 -0.233 0.281  0.027  
ATOM   2551  C  CB  . LYS A 1 354 ? -23.454 28.375  10.777  1    116.84 ? 343 LYS A CB  1 -0.215 0.26   0.027  
ATOM   2552  C  CG  . LYS A 1 354 ? -23.327 26.897  11.036  1    113.11 ? 343 LYS A CG  1 -0.214 0.246  0.028  
ATOM   2553  C  CD  . LYS A 1 354 ? -24.511 26.386  11.853  1    115.38 ? 343 LYS A CD  1 -0.225 0.242  0.03   
ATOM   2554  C  CE  . LYS A 1 354 ? -24.442 26.854  13.311  1    116.2  ? 343 LYS A CE  1 -0.224 0.246  0.033  
ATOM   2555  N  NZ  . LYS A 1 354 ? -23.45  26.075  14.121  1    111.4  ? 343 LYS A NZ  1 -0.215 0.239  0.035  
ATOM   2556  N  N   . PHE A 1 355 ? -24.504 30.967  8.868   1    115.23 ? 344 PHE A N   1 -0.225 0.284  0.022  
ATOM   2557  C  CA  . PHE A 1 355 ? -24.775 32.407  8.836   1    118.18 ? 344 PHE A CA  1 -0.227 0.297  0.022  
ATOM   2558  C  C   . PHE A 1 355 ? -26.231 32.59   8.421   1    122.19 ? 344 PHE A C   1 -0.24  0.299  0.021  
ATOM   2559  O  O   . PHE A 1 355 ? -26.589 32.448  7.246   1    125.21 ? 344 PHE A O   1 -0.244 0.297  0.018  
ATOM   2560  C  CB  . PHE A 1 355 ? -23.808 33.106  7.887   1    122.63 ? 344 PHE A CB  1 -0.218 0.303  0.02   
ATOM   2561  C  CG  . PHE A 1 355 ? -24.035 34.589  7.75    1    125.93 ? 344 PHE A CG  1 -0.22  0.317  0.019  
ATOM   2562  C  CD1 . PHE A 1 355 ? -25.085 35.09   6.977   1    127.8  ? 344 PHE A CD1 1 -0.23  0.322  0.017  
ATOM   2563  C  CD2 . PHE A 1 355 ? -23.169 35.486  8.365   1    129.12 ? 344 PHE A CD2 1 -0.212 0.325  0.021  
ATOM   2564  C  CE1 . PHE A 1 355 ? -25.29  36.465  6.84    1    129.33 ? 344 PHE A CE1 1 -0.232 0.334  0.017  
ATOM   2565  C  CE2 . PHE A 1 355 ? -23.356 36.861  8.236   1    132.23 ? 344 PHE A CE2 1 -0.214 0.338  0.021  
ATOM   2566  C  CZ  . PHE A 1 355 ? -24.416 37.353  7.468   1    132.6  ? 344 PHE A CZ  1 -0.224 0.342  0.019  
ATOM   2567  N  N   . VAL A 1 356 ? -27.081 32.904  9.392   1    118.11 ? 345 VAL A N   1 -0.248 0.302  0.023  
ATOM   2568  C  CA  . VAL A 1 356 ? -28.519 32.986  9.192   1    116.47 ? 345 VAL A CA  1 -0.261 0.302  0.023  
ATOM   2569  C  C   . VAL A 1 356 ? -28.959 34.413  9.494   1    121.43 ? 345 VAL A C   1 -0.265 0.315  0.024  
ATOM   2570  O  O   . VAL A 1 356 ? -28.608 34.967  10.542  1    125.98 ? 345 VAL A O   1 -0.262 0.32   0.026  
ATOM   2571  C  CB  . VAL A 1 356 ? -29.259 31.966  10.075  1    115.44 ? 345 VAL A CB  1 -0.268 0.293  0.025  
ATOM   2572  C  CG1 . VAL A 1 356 ? -30.677 31.783  9.607   1    114.07 ? 345 VAL A CG1 1 -0.281 0.291  0.024  
ATOM   2573  C  CG2 . VAL A 1 356 ? -28.517 30.638  10.057  1    115.54 ? 345 VAL A CG2 1 -0.261 0.281  0.025  
ATOM   2574  N  N   . ASN A 1 357 ? -29.724 34.998  8.562   1    127.25 ? 346 ASN A N   1 -0.272 0.321  0.021  
ATOM   2575  C  CA  . ASN A 1 357 ? -30.113 36.41   8.484   1    125.77 ? 346 ASN A CA  1 -0.276 0.334  0.021  
ATOM   2576  C  C   . ASN A 1 357 ? -29.154 37.365  9.198   1    129.49 ? 346 ASN A C   1 -0.267 0.342  0.023  
ATOM   2577  O  O   . ASN A 1 357 ? -29.458 37.887  10.28   1    130.67 ? 346 ASN A O   1 -0.27  0.347  0.026  
ATOM   2578  C  CB  . ASN A 1 357 ? -31.56  36.595  8.981   1    123.76 ? 346 ASN A CB  1 -0.289 0.335  0.022  
ATOM   2579  C  CG  . ASN A 1 357 ? -31.811 36.001  10.369  1    127.88 ? 346 ASN A CG  1 -0.292 0.33   0.026  
ATOM   2580  O  OD1 . ASN A 1 357 ? -30.935 35.978  11.231  1    131.47 ? 346 ASN A OD1 1 -0.283 0.33   0.028  
ATOM   2581  N  ND2 . ASN A 1 357 ? -33.04  35.536  10.589  1    127.67 ? 346 ASN A ND2 1 -0.303 0.326  0.026  
ATOM   2582  N  N   . GLY A 1 358 ? -27.98  37.589  8.599   1    124.79 ? 347 GLY A N   1 -0.256 0.344  0.021  
ATOM   2583  C  CA  . GLY A 1 358 ? -27.085 38.649  9.014   1    127.01 ? 347 GLY A CA  1 -0.248 0.354  0.023  
ATOM   2584  C  C   . GLY A 1 358 ? -26.114 38.323  10.138  1    129.47 ? 347 GLY A C   1 -0.239 0.351  0.025  
ATOM   2585  O  O   . GLY A 1 358 ? -25.163 39.087  10.341  1    129.32 ? 347 GLY A O   1 -0.231 0.358  0.026  
ATOM   2586  N  N   . ARG A 1 359 ? -26.326 37.238  10.89   1    127.64 ? 348 ARG A N   1 -0.241 0.341  0.027  
ATOM   2587  C  CA  . ARG A 1 359 ? -25.39  36.882  11.956  1    130.51 ? 348 ARG A CA  1 -0.233 0.338  0.03   
ATOM   2588  C  C   . ARG A 1 359 ? -25.268 35.369  12.066  1    126.81 ? 348 ARG A C   1 -0.232 0.324  0.03   
ATOM   2589  O  O   . ARG A 1 359 ? -26.14  34.617  11.62   1    124.57 ? 348 ARG A O   1 -0.24  0.317  0.029  
ATOM   2590  C  CB  . ARG A 1 359 ? -25.797 37.469  13.321  1    133.59 ? 348 ARG A CB  1 -0.236 0.343  0.033  
ATOM   2591  C  CG  . ARG A 1 359 ? -26.647 36.531  14.182  1    131.83 ? 348 ARG A CG  1 -0.244 0.335  0.035  
ATOM   2592  C  CD  . ARG A 1 359 ? -26.8   37.02   15.629  1    138.26 ? 348 ARG A CD  1 -0.246 0.339  0.039  
ATOM   2593  N  NE  . ARG A 1 359 ? -27.401 38.347  15.724  1    143.25 ? 348 ARG A NE  1 -0.251 0.351  0.039  
ATOM   2594  C  CZ  . ARG A 1 359 ? -26.778 39.429  16.174  1    142.64 ? 348 ARG A CZ  1 -0.245 0.361  0.04   
ATOM   2595  N  NH1 . ARG A 1 359 ? -25.537 39.373  16.635  1    136.49 ? 348 ARG A NH1 1 -0.234 0.361  0.042  
ATOM   2596  N  NH2 . ARG A 1 359 ? -27.417 40.598  16.166  1    143.05 ? 348 ARG A NH2 1 -0.251 0.372  0.04   
ATOM   2597  N  N   . MET A 1 360 ? -24.166 34.934  12.682  1    125.84 ? 349 MET A N   1 -0.221 0.32   0.032  
ATOM   2598  C  CA  . MET A 1 360 ? -23.884 33.512  12.844  1    121.01 ? 349 MET A CA  1 -0.219 0.307  0.032  
ATOM   2599  C  C   . MET A 1 360 ? -24.801 32.912  13.899  1    117.88 ? 349 MET A C   1 -0.227 0.302  0.035  
ATOM   2600  O  O   . MET A 1 360 ? -24.804 33.347  15.052  1    119.59 ? 349 MET A O   1 -0.227 0.306  0.038  
ATOM   2601  C  CB  . MET A 1 360 ? -22.422 33.299  13.224  1    122.07 ? 349 MET A CB  1 -0.205 0.305  0.033  
ATOM   2602  C  CG  . MET A 1 360 ? -21.443 33.431  12.06   1    119.94 ? 349 MET A CG  1 -0.197 0.306  0.03   
ATOM   2603  S  SD  . MET A 1 360 ? -21.698 32.185  10.777  1    125.95 ? 349 MET A SD  1 -0.199 0.295  0.027  
ATOM   2604  C  CE  . MET A 1 360 ? -20.747 30.808  11.408  1    116.38 ? 349 MET A CE  1 -0.19  0.282  0.028  
ATOM   2605  N  N   . MET A 1 361 ? -25.576 31.916  13.495  1    116.39 ? 350 MET A N   1 -0.234 0.292  0.034  
ATOM   2606  C  CA  . MET A 1 361 ? -26.487 31.23   14.394  1    118.79 ? 350 MET A CA  1 -0.243 0.286  0.036  
ATOM   2607  C  C   . MET A 1 361 ? -25.727 30.63   15.578  1    119.19 ? 350 MET A C   1 -0.236 0.281  0.039  
ATOM   2608  O  O   . MET A 1 361 ? -24.568 30.214  15.457  1    112.76 ? 350 MET A O   1 -0.225 0.277  0.039  
ATOM   2609  C  CB  . MET A 1 361 ? -27.244 30.163  13.601  1    118.18 ? 350 MET A CB  1 -0.25  0.276  0.034  
ATOM   2610  C  CG  . MET A 1 361 ? -27.856 29.039  14.398  1    120.24 ? 350 MET A CG  1 -0.255 0.266  0.036  
ATOM   2611  S  SD  . MET A 1 361 ? -28.334 27.713  13.276  1    123.9  ? 350 MET A SD  1 -0.26  0.254  0.033  
ATOM   2612  C  CE  . MET A 1 361 ? -29.878 28.365  12.647  1    119.43 ? 350 MET A CE  1 -0.274 0.26   0.032  
ATOM   2613  N  N   . GLY A 1 362 ? -26.391 30.609  16.741  1    123.63 ? 351 GLY A N   1 -0.242 0.281  0.042  
ATOM   2614  C  CA  . GLY A 1 362 ? -25.781 30.223  17.995  1    116.66 ? 351 GLY A CA  1 -0.236 0.277  0.045  
ATOM   2615  C  C   . GLY A 1 362 ? -26.324 28.912  18.551  1    116.49 ? 351 GLY A C   1 -0.241 0.265  0.046  
ATOM   2616  O  O   . GLY A 1 362 ? -27.322 28.366  18.084  1    119.32 ? 351 GLY A O   1 -0.25  0.26   0.045  
ATOM   2617  N  N   . LYS A 1 363 ? -25.654 28.441  19.613  1    120    ? 352 LYS A N   1 -0.235 0.261  0.049  
ATOM   2618  C  CA  . LYS A 1 363 ? -25.845 27.079  20.121  1    115.42 ? 352 LYS A CA  1 -0.237 0.248  0.05   
ATOM   2619  C  C   . LYS A 1 363 ? -27.296 26.788  20.514  1    110.42 ? 352 LYS A C   1 -0.25  0.245  0.051  
ATOM   2620  O  O   . LYS A 1 363 ? -27.734 25.635  20.45   1    110.9  ? 352 LYS A O   1 -0.254 0.235  0.051  
ATOM   2621  C  CB  . LYS A 1 363 ? -24.886 26.842  21.296  1    110.41 ? 352 LYS A CB  1 -0.228 0.246  0.053  
ATOM   2622  C  CG  . LYS A 1 363 ? -25.156 25.595  22.157  1    126.68 ? 352 LYS A CG  1 -0.231 0.235  0.055  
ATOM   2623  C  CD  . LYS A 1 363 ? -25.142 24.283  21.362  1    132.57 ? 352 LYS A CD  1 -0.23  0.223  0.053  
ATOM   2624  C  CE  . LYS A 1 363 ? -25.956 23.184  22.078  1    131.22 ? 352 LYS A CE  1 -0.238 0.212  0.055  
ATOM   2625  N  NZ  . LYS A 1 363 ? -26.71  22.317  21.101  1    126.43 ? 352 LYS A NZ  1 -0.245 0.205  0.053  
ATOM   2626  N  N   . THR A 1 364 ? -28.068 27.797  20.905  1    110.38 ? 353 THR A N   1 -0.257 0.255  0.052  
ATOM   2627  C  CA  . THR A 1 364 ? -29.469 27.53   21.213  1    115.03 ? 353 THR A CA  1 -0.27  0.252  0.053  
ATOM   2628  C  C   . THR A 1 364 ? -30.247 27.259  19.936  1    115.04 ? 353 THR A C   1 -0.277 0.25   0.05   
ATOM   2629  O  O   . THR A 1 364 ? -30.895 26.215  19.793  1    116.1  ? 353 THR A O   1 -0.283 0.24   0.049  
ATOM   2630  C  CB  . THR A 1 364 ? -30.087 28.702  21.986  1    122.74 ? 353 THR A CB  1 -0.276 0.263  0.055  
ATOM   2631  O  OG1 . THR A 1 364 ? -29.331 28.94   23.186  1    126.64 ? 353 THR A OG1 1 -0.269 0.265  0.058  
ATOM   2632  C  CG2 . THR A 1 364 ? -31.561 28.402  22.351  1    111.35 ? 353 THR A CG2 1 -0.289 0.26   0.056  
ATOM   2633  N  N   . ALA A 1 365 ? -30.18  28.194  18.989  1    114.29 ? 354 ALA A N   1 -0.277 0.258  0.047  
ATOM   2634  C  CA  . ALA A 1 365 ? -30.868 28.011  17.721  1    116.69 ? 354 ALA A CA  1 -0.283 0.257  0.044  
ATOM   2635  C  C   . ALA A 1 365 ? -30.313 26.808  16.957  1    116.57 ? 354 ALA A C   1 -0.278 0.246  0.042  
ATOM   2636  O  O   . ALA A 1 365 ? -31.075 26.035  16.363  1    114.01 ? 354 ALA A O   1 -0.285 0.239  0.041  
ATOM   2637  C  CB  . ALA A 1 365 ? -30.757 29.295  16.904  1    124.26 ? 354 ALA A CB  1 -0.282 0.268  0.042  
ATOM   2638  N  N   . ALA A 1 366 ? -28.988 26.618  16.989  1    112.09 ? 355 ALA A N   1 -0.266 0.244  0.042  
ATOM   2639  C  CA  . ALA A 1 366 ? -28.37  25.514  16.263  1    108.57 ? 355 ALA A CA  1 -0.26  0.234  0.041  
ATOM   2640  C  C   . ALA A 1 366 ? -28.933 24.166  16.687  1    109.75 ? 355 ALA A C   1 -0.265 0.221  0.042  
ATOM   2641  O  O   . ALA A 1 366 ? -29.054 23.26   15.862  1    114.19 ? 355 ALA A O   1 -0.266 0.213  0.04   
ATOM   2642  C  CB  . ALA A 1 366 ? -26.854 25.538  16.45   1    110.46 ? 355 ALA A CB  1 -0.246 0.234  0.041  
ATOM   2643  N  N   . HIS A 1 367 ? -29.294 24.001  17.95   1    115.71 ? 356 HIS A N   1 -0.268 0.22   0.045  
ATOM   2644  C  CA  . HIS A 1 367 ? -29.846 22.715  18.35   1    119.08 ? 356 HIS A CA  1 -0.274 0.208  0.046  
ATOM   2645  C  C   . HIS A 1 367 ? -31.311 22.569  17.98   1    119.12 ? 356 HIS A C   1 -0.287 0.207  0.045  
ATOM   2646  O  O   . HIS A 1 367 ? -31.817 21.442  17.921  1    117.46 ? 356 HIS A O   1 -0.292 0.196  0.045  
ATOM   2647  C  CB  . HIS A 1 367 ? -29.682 22.493  19.85   1    121.87 ? 356 HIS A CB  1 -0.272 0.206  0.05   
ATOM   2648  C  CG  . HIS A 1 367 ? -30.198 21.169  20.315  1    126.44 ? 356 HIS A CG  1 -0.277 0.194  0.051  
ATOM   2649  N  ND1 . HIS A 1 367 ? -31.515 20.967  20.679  1    128.14 ? 356 HIS A ND1 1 -0.289 0.192  0.052  
ATOM   2650  C  CD2 . HIS A 1 367 ? -29.58  19.973  20.461  1    127.03 ? 356 HIS A CD2 1 -0.271 0.183  0.051  
ATOM   2651  C  CE1 . HIS A 1 367 ? -31.681 19.708  21.046  1    128.68 ? 356 HIS A CE1 1 -0.29  0.181  0.053  
ATOM   2652  N  NE2 . HIS A 1 367 ? -30.523 19.083  20.923  1    135.75 ? 356 HIS A NE2 1 -0.28  0.175  0.052  
ATOM   2653  N  N   . GLN A 1 368 ? -32.007 23.672  17.734  1    119.91 ? 357 GLN A N   1 -0.293 0.217  0.044  
ATOM   2654  C  CA  . GLN A 1 368 ? -33.41  23.588  17.357  1    121.88 ? 357 GLN A CA  1 -0.306 0.216  0.043  
ATOM   2655  C  C   . GLN A 1 368 ? -33.632 23.485  15.858  1    115.34 ? 357 GLN A C   1 -0.308 0.215  0.04   
ATOM   2656  O  O   . GLN A 1 368 ? -34.755 23.165  15.452  1    115.63 ? 357 GLN A O   1 -0.318 0.212  0.039  
ATOM   2657  C  CB  . GLN A 1 368 ? -34.191 24.794  17.9    1    121.93 ? 357 GLN A CB  1 -0.313 0.227  0.045  
ATOM   2658  C  CG  . GLN A 1 368 ? -34.5   24.725  19.384  1    123.65 ? 357 GLN A CG  1 -0.316 0.227  0.048  
ATOM   2659  C  CD  . GLN A 1 368 ? -34.881 23.328  19.829  1    130.23 ? 357 GLN A CD  1 -0.32  0.214  0.05   
ATOM   2660  O  OE1 . GLN A 1 368 ? -34.007 22.504  20.141  1    131.24 ? 357 GLN A OE1 1 -0.312 0.206  0.05   
ATOM   2661  N  NE2 . GLN A 1 368 ? -36.19  23.041  19.86   1    126.89 ? 357 GLN A NE2 1 -0.332 0.211  0.05   
ATOM   2662  N  N   . PHE A 1 369 ? -32.598 23.75   15.033  1    112.33 ? 358 PHE A N   1 -0.299 0.218  0.038  
ATOM   2663  C  CA  . PHE A 1 369 ? -32.71  23.783  13.572  1    112.7  ? 358 PHE A CA  1 -0.3   0.218  0.034  
ATOM   2664  C  C   . PHE A 1 369 ? -31.79  22.809  12.844  1    107.21 ? 358 PHE A C   1 -0.291 0.209  0.032  
ATOM   2665  O  O   . PHE A 1 369 ? -32.069 22.478  11.691  1    102.09 ? 358 PHE A O   1 -0.294 0.206  0.029  
ATOM   2666  C  CB  . PHE A 1 369 ? -32.422 25.194  13.027  1    107.65 ? 358 PHE A CB  1 -0.297 0.231  0.033  
ATOM   2667  C  CG  . PHE A 1 369 ? -33.387 26.249  13.503  1    112.25 ? 358 PHE A CG  1 -0.306 0.241  0.034  
ATOM   2668  C  CD1 . PHE A 1 369 ? -34.76  26.044  13.431  1    110.16 ? 358 PHE A CD1 1 -0.319 0.239  0.034  
ATOM   2669  C  CD2 . PHE A 1 369 ? -32.915 27.443  14.035  1    112.83 ? 358 PHE A CD2 1 -0.302 0.251  0.035  
ATOM   2670  C  CE1 . PHE A 1 369 ? -35.642 27.012  13.872  1    106.71 ? 358 PHE A CE1 1 -0.327 0.248  0.035  
ATOM   2671  C  CE2 . PHE A 1 369 ? -33.788 28.41   14.476  1    110.2  ? 358 PHE A CE2 1 -0.31  0.26   0.036  
ATOM   2672  C  CZ  . PHE A 1 369 ? -35.156 28.194  14.391  1    111.46 ? 358 PHE A CZ  1 -0.322 0.258  0.036  
ATOM   2673  N  N   . ARG A 1 370 ? -30.718 22.347  13.471  1    106.99 ? 359 ARG A N   1 -0.282 0.205  0.034  
ATOM   2674  C  CA  . ARG A 1 370 ? -29.773 21.43   12.861  1    99.21  ? 359 ARG A CA  1 -0.273 0.196  0.032  
ATOM   2675  C  C   . ARG A 1 370 ? -29.861 20.049  13.517  1    102.14 ? 359 ARG A C   1 -0.274 0.184  0.034  
ATOM   2676  O  O   . ARG A 1 370 ? -30.768 19.759  14.309  1    107.97 ? 359 ARG A O   1 -0.282 0.181  0.036  
ATOM   2677  C  CB  . ARG A 1 370 ? -28.374 22.021  12.961  1    100.33 ? 359 ARG A CB  1 -0.26  0.202  0.032  
ATOM   2678  C  CG  . ARG A 1 370 ? -28.238 23.373  12.272  1    104.3  ? 359 ARG A CG  1 -0.259 0.214  0.031  
ATOM   2679  C  CD  . ARG A 1 370 ? -28.114 23.224  10.766  1    92.24  ? 359 ARG A CD  1 -0.258 0.213  0.027  
ATOM   2680  N  NE  . ARG A 1 370 ? -28.006 24.512  10.095  1    96.24  ? 359 ARG A NE  1 -0.257 0.225  0.025  
ATOM   2681  C  CZ  . ARG A 1 370 ? -29.043 25.274  9.767   1    93.54  ? 359 ARG A CZ  1 -0.266 0.232  0.024  
ATOM   2682  N  NH1 . ARG A 1 370 ? -30.28  24.934  10.094  1    86.14  ? 359 ARG A NH1 1 -0.277 0.228  0.025  
ATOM   2683  N  NH2 . ARG A 1 370 ? -28.834 26.4    9.087   1    96.37  ? 359 ARG A NH2 1 -0.264 0.242  0.023  
ATOM   2684  N  N   . PHE A 1 371 ? -28.899 19.193  13.2    1    99.56  ? 360 PHE A N   1 -0.265 0.176  0.033  
ATOM   2685  C  CA  . PHE A 1 371 ? -28.937 17.796  13.596  1    98.1   ? 360 PHE A CA  1 -0.265 0.163  0.034  
ATOM   2686  C  C   . PHE A 1 371 ? -27.752 17.488  14.499  1    98.21  ? 360 PHE A C   1 -0.254 0.16   0.036  
ATOM   2687  O  O   . PHE A 1 371 ? -26.699 18.127  14.401  1    98.5   ? 360 PHE A O   1 -0.245 0.166  0.036  
ATOM   2688  C  CB  . PHE A 1 371 ? -28.897 16.86   12.358  1    106.79 ? 360 PHE A CB  1 -0.265 0.155  0.031  
ATOM   2689  C  CG  . PHE A 1 371 ? -30.041 17.056  11.392  1    100.91 ? 360 PHE A CG  1 -0.275 0.156  0.028  
ATOM   2690  C  CD1 . PHE A 1 371 ? -31.267 17.542  11.825  1    103.26 ? 360 PHE A CD1 1 -0.287 0.161  0.03   
ATOM   2691  C  CD2 . PHE A 1 371 ? -29.882 16.757  10.05   1    100.86 ? 360 PHE A CD2 1 -0.274 0.154  0.025  
ATOM   2692  C  CE1 . PHE A 1 371 ? -32.313 17.728  10.934  1    102.92 ? 360 PHE A CE1 1 -0.296 0.162  0.027  
ATOM   2693  C  CE2 . PHE A 1 371 ? -30.925 16.934  9.152   1    100.98 ? 360 PHE A CE2 1 -0.283 0.155  0.023  
ATOM   2694  C  CZ  . PHE A 1 371 ? -32.143 17.414  9.595   1    103.83 ? 360 PHE A CZ  1 -0.295 0.16   0.024  
ATOM   2695  N  N   . ASN A 1 372 ? -27.926 16.491  15.369  1    97.17  ? 361 ASN A N   1 -0.256 0.151  0.038  
ATOM   2696  C  CA  . ASN A 1 372 ? -26.852 16.026  16.241  1    99.72  ? 361 ASN A CA  1 -0.246 0.147  0.041  
ATOM   2697  C  C   . ASN A 1 372 ? -26.702 14.527  16.059  1    96.17  ? 361 ASN A C   1 -0.245 0.133  0.04   
ATOM   2698  O  O   . ASN A 1 372 ? -27.606 13.856  15.556  1    98.21  ? 361 ASN A O   1 -0.253 0.127  0.039  
ATOM   2699  C  CB  . ASN A 1 372 ? -27.082 16.379  17.741  1    93.65  ? 361 ASN A CB  1 -0.248 0.15   0.044  
ATOM   2700  C  CG  . ASN A 1 372 ? -28.292 15.663  18.378  1    97.25  ? 361 ASN A CG  1 -0.259 0.144  0.046  
ATOM   2701  O  OD1 . ASN A 1 372 ? -28.96  14.821  17.786  1    92.1   ? 361 ASN A OD1 1 -0.265 0.136  0.044  
ATOM   2702  N  ND2 . ASN A 1 372 ? -28.538 15.991  19.638  1    120.88 ? 361 ASN A ND2 1 -0.262 0.147  0.049  
ATOM   2703  N  N   . ASP A 1 373 ? -25.538 14.02   16.488  1    93.95  ? 362 ASP A N   1 -0.234 0.128  0.041  
ATOM   2704  C  CA  . ASP A 1 373 ? -25.203 12.605  16.311  1    95.51  ? 362 ASP A CA  1 -0.231 0.116  0.041  
ATOM   2705  C  C   . ASP A 1 373 ? -26.346 11.696  16.732  1    98.72  ? 362 ASP A C   1 -0.241 0.107  0.042  
ATOM   2706  O  O   . ASP A 1 373 ? -26.493 10.582  16.203  1    92.11  ? 362 ASP A O   1 -0.243 0.097  0.04   
ATOM   2707  C  CB  . ASP A 1 373 ? -23.94  12.281  17.097  1    93.92  ? 362 ASP A CB  1 -0.219 0.113  0.043  
ATOM   2708  C  CG  . ASP A 1 373 ? -22.861 13.322  16.894  1    100.37 ? 362 ASP A CG  1 -0.21  0.122  0.042  
ATOM   2709  O  OD1 . ASP A 1 373 ? -23.127 14.287  16.14   1    100.6  ? 362 ASP A OD1 1 -0.212 0.131  0.04   
ATOM   2710  O  OD2 . ASP A 1 373 ? -21.765 13.192  17.486  1    102.94 ? 362 ASP A OD2 1 -0.199 0.121  0.044  
ATOM   2711  N  N   . GLY A 1 374 ? -27.177 12.155  17.668  1    100.64 ? 363 GLY A N   1 -0.249 0.111  0.044  
ATOM   2712  C  CA  . GLY A 1 374 ? -28.358 11.396  18.024  1    102.62 ? 363 GLY A CA  1 -0.26  0.104  0.045  
ATOM   2713  C  C   . GLY A 1 374 ? -29.275 11.195  16.84   1    94.36  ? 363 GLY A C   1 -0.268 0.103  0.042  
ATOM   2714  O  O   . GLY A 1 374 ? -29.644 10.064  16.51   1    92.54  ? 363 GLY A O   1 -0.272 0.092  0.041  
ATOM   2715  N  N   . ASP A 1 375 ? -29.632 12.298  16.172  1    97.82  ? 364 ASP A N   1 -0.272 0.113  0.04   
ATOM   2716  C  CA  . ASP A 1 375 ? -30.465 12.232  14.971  1    101.32 ? 364 ASP A CA  1 -0.279 0.112  0.037  
ATOM   2717  C  C   . ASP A 1 375 ? -29.813 11.376  13.886  1    101.37 ? 364 ASP A C   1 -0.273 0.104  0.035  
ATOM   2718  O  O   . ASP A 1 375 ? -30.431 10.443  13.351  1    99.41  ? 364 ASP A O   1 -0.279 0.096  0.033  
ATOM   2719  C  CB  . ASP A 1 375 ? -30.713 13.635  14.418  1    100.86 ? 364 ASP A CB  1 -0.281 0.125  0.036  
ATOM   2720  C  CG  . ASP A 1 375 ? -31.193 14.622  15.457  1    97.75  ? 364 ASP A CG  1 -0.286 0.134  0.039  
ATOM   2721  O  OD1 . ASP A 1 375 ? -32.246 14.382  16.102  1    99.67  ? 364 ASP A OD1 1 -0.296 0.132  0.04   
ATOM   2722  O  OD2 . ASP A 1 375 ? -30.519 15.671  15.574  1    94.32  ? 364 ASP A OD2 1 -0.28  0.144  0.039  
ATOM   2723  N  N   . LEU A 1 376 ? -28.569 11.699  13.527  1    98.26  ? 365 LEU A N   1 -0.262 0.107  0.034  
ATOM   2724  C  CA  . LEU A 1 376 ? -27.931 11.041  12.392  1    98.86  ? 365 LEU A CA  1 -0.256 0.101  0.031  
ATOM   2725  C  C   . LEU A 1 376 ? -27.822 9.541   12.61   1    99.78  ? 365 LEU A C   1 -0.255 0.087  0.031  
ATOM   2726  O  O   . LEU A 1 376 ? -28.245 8.746   11.761  1    101.74 ? 365 LEU A O   1 -0.259 0.08   0.029  
ATOM   2727  C  CB  . LEU A 1 376 ? -26.552 11.645  12.15   1    100.46 ? 365 LEU A CB  1 -0.243 0.107  0.03   
ATOM   2728  C  CG  . LEU A 1 376 ? -26.525 13.108  11.711  1    100.39 ? 365 LEU A CG  1 -0.243 0.12   0.029  
ATOM   2729  C  CD1 . LEU A 1 376 ? -25.209 13.357  10.998  1    96.98  ? 365 LEU A CD1 1 -0.231 0.122  0.027  
ATOM   2730  C  CD2 . LEU A 1 376 ? -27.724 13.446  10.833  1    96.87  ? 365 LEU A CD2 1 -0.254 0.123  0.027  
ATOM   2731  N  N   . GLY A 1 377 ? -27.239 9.137   13.744  1    105.04 ? 366 GLY A N   1 -0.25  0.084  0.034  
ATOM   2732  C  CA  . GLY A 1 377 ? -27.09  7.724   14.046  1    98.14  ? 366 GLY A CA  1 -0.248 0.071  0.035  
ATOM   2733  C  C   . GLY A 1 377 ? -28.395 6.96    13.993  1    97.35  ? 366 GLY A C   1 -0.26  0.064  0.035  
ATOM   2734  O  O   . GLY A 1 377 ? -28.417 5.799   13.583  1    104.1  ? 366 GLY A O   1 -0.26  0.053  0.034  
ATOM   2735  N  N   . TYR A 1 378 ? -29.497 7.588   14.405  1    96.04  ? 367 TYR A N   1 -0.27  0.07   0.036  
ATOM   2736  C  CA  . TYR A 1 378 ? -30.791 6.931   14.273  1    99.97  ? 367 TYR A CA  1 -0.282 0.064  0.036  
ATOM   2737  C  C   . TYR A 1 378 ? -31.149 6.76    12.807  1    104.5  ? 367 TYR A C   1 -0.285 0.062  0.032  
ATOM   2738  O  O   . TYR A 1 378 ? -31.484 5.653   12.368  1    106.45 ? 367 TYR A O   1 -0.289 0.052  0.031  
ATOM   2739  C  CB  . TYR A 1 378 ? -31.867 7.734   14.995  1    101.97 ? 367 TYR A CB  1 -0.292 0.071  0.037  
ATOM   2740  C  CG  . TYR A 1 378 ? -33.201 7.035   15.054  1    104.78 ? 367 TYR A CG  1 -0.304 0.064  0.038  
ATOM   2741  C  CD1 . TYR A 1 378 ? -34.072 7.056   13.966  1    107.57 ? 367 TYR A CD1 1 -0.312 0.065  0.035  
ATOM   2742  C  CD2 . TYR A 1 378 ? -33.591 6.349   16.193  1    107.92 ? 367 TYR A CD2 1 -0.308 0.058  0.04   
ATOM   2743  C  CE1 . TYR A 1 378 ? -35.298 6.416   14.02   1    110.6  ? 367 TYR A CE1 1 -0.323 0.059  0.035  
ATOM   2744  C  CE2 . TYR A 1 378 ? -34.813 5.707   16.258  1    111.34 ? 367 TYR A CE2 1 -0.319 0.052  0.041  
ATOM   2745  C  CZ  . TYR A 1 378 ? -35.665 5.745   15.17   1    106.87 ? 367 TYR A CZ  1 -0.327 0.053  0.038  
ATOM   2746  O  OH  . TYR A 1 378 ? -36.887 5.11    15.231  1    110.36 ? 367 TYR A OH  1 -0.338 0.047  0.038  
ATOM   2747  N  N   . PHE A 1 379 ? -31.074 7.855   12.041  1    106.05 ? 368 PHE A N   1 -0.285 0.072  0.03   
ATOM   2748  C  CA  . PHE A 1 379 ? -31.385 7.857   10.612  1    104.27 ? 368 PHE A CA  1 -0.288 0.072  0.026  
ATOM   2749  C  C   . PHE A 1 379 ? -30.651 6.733   9.886   1    103.3  ? 368 PHE A C   1 -0.281 0.062  0.025  
ATOM   2750  O  O   . PHE A 1 379 ? -31.274 5.792   9.376   1    101.8  ? 368 PHE A O   1 -0.287 0.053  0.023  
ATOM   2751  C  CB  . PHE A 1 379 ? -31.018 9.235   10.048  1    107.96 ? 368 PHE A CB  1 -0.284 0.085  0.025  
ATOM   2752  C  CG  . PHE A 1 379 ? -31.364 9.451   8.592   1    102.67 ? 368 PHE A CG  1 -0.287 0.087  0.021  
ATOM   2753  C  CD1 . PHE A 1 379 ? -32.636 9.855   8.218   1    99.61  ? 368 PHE A CD1 1 -0.299 0.09   0.021  
ATOM   2754  C  CD2 . PHE A 1 379 ? -30.386 9.326   7.613   1    101.78 ? 368 PHE A CD2 1 -0.278 0.085  0.019  
ATOM   2755  C  CE1 . PHE A 1 379 ? -32.936 10.09   6.886   1    103.46 ? 368 PHE A CE1 1 -0.302 0.092  0.017  
ATOM   2756  C  CE2 . PHE A 1 379 ? -30.677 9.559   6.275   1    104.44 ? 368 PHE A CE2 1 -0.281 0.088  0.016  
ATOM   2757  C  CZ  . PHE A 1 379 ? -31.953 9.938   5.91    1    104.54 ? 368 PHE A CZ  1 -0.293 0.091  0.015  
ATOM   2758  N  N   . TYR A 1 380 ? -29.315 6.797   9.868   1    101.12 ? 369 TYR A N   1 -0.269 0.062  0.025  
ATOM   2759  C  CA  . TYR A 1 380 ? -28.537 5.781   9.169   1    102.99 ? 369 TYR A CA  1 -0.262 0.053  0.023  
ATOM   2760  C  C   . TYR A 1 380 ? -28.897 4.377   9.64    1    106.47 ? 369 TYR A C   1 -0.265 0.04   0.024  
ATOM   2761  O  O   . TYR A 1 380 ? -29.03  3.462   8.821   1    107.76 ? 369 TYR A O   1 -0.266 0.032  0.022  
ATOM   2762  C  CB  . TYR A 1 380 ? -27.04  6.038   9.348   1    103.25 ? 369 TYR A CB  1 -0.248 0.055  0.023  
ATOM   2763  C  CG  . TYR A 1 380 ? -26.549 7.267   8.624   1    107.01 ? 369 TYR A CG  1 -0.243 0.067  0.022  
ATOM   2764  C  CD1 . TYR A 1 380 ? -26.687 7.388   7.231   1    105.22 ? 369 TYR A CD1 1 -0.245 0.068  0.018  
ATOM   2765  C  CD2 . TYR A 1 380 ? -25.938 8.306   9.324   1    99.03  ? 369 TYR A CD2 1 -0.238 0.076  0.023  
ATOM   2766  C  CE1 . TYR A 1 380 ? -26.238 8.526   6.55    1    105.2  ? 369 TYR A CE1 1 -0.24  0.078  0.016  
ATOM   2767  C  CE2 . TYR A 1 380 ? -25.482 9.437   8.67    1    104.87 ? 369 TYR A CE2 1 -0.234 0.086  0.022  
ATOM   2768  C  CZ  . TYR A 1 380 ? -25.632 9.548   7.276   1    111.53 ? 369 TYR A CZ  1 -0.235 0.087  0.018  
ATOM   2769  O  OH  . TYR A 1 380 ? -25.182 10.678  6.614   1    101.26 ? 369 TYR A OH  1 -0.231 0.098  0.017  
ATOM   2770  N  N   . GLU A 1 381 ? -29.072 4.188   10.954  1    104.1  ? 370 GLU A N   1 -0.266 0.038  0.027  
ATOM   2771  C  CA  . GLU A 1 381 ? -29.43  2.868   11.468  1    101.29 ? 370 GLU A CA  1 -0.27  0.026  0.029  
ATOM   2772  C  C   . GLU A 1 381 ? -30.796 2.425   10.96   1    102.16 ? 370 GLU A C   1 -0.282 0.022  0.027  
ATOM   2773  O  O   . GLU A 1 381 ? -31.004 1.241   10.665  1    105.04 ? 370 GLU A O   1 -0.284 0.011  0.027  
ATOM   2774  C  CB  . GLU A 1 381 ? -29.416 2.869   12.996  1    106.91 ? 370 GLU A CB  1 -0.27  0.026  0.032  
ATOM   2775  C  CG  . GLU A 1 381 ? -28.631 1.713   13.634  1    110.61 ? 370 GLU A CG  1 -0.262 0.016  0.034  
ATOM   2776  C  CD  . GLU A 1 381 ? -29.43  0.414   13.73   1    113.74 ? 370 GLU A CD  1 -0.27  0.004  0.034  
ATOM   2777  O  OE1 . GLU A 1 381 ? -30.685 0.435   13.6    1    111.67 ? 370 GLU A OE1 1 -0.281 0.004  0.034  
ATOM   2778  O  OE2 . GLU A 1 381 ? -28.783 -0.635  13.959  1    117.12 ? 370 GLU A OE2 1 -0.264 -0.006 0.035  
ATOM   2779  N  N   . SER A 1 382 ? -31.743 3.356   10.856  1    98.13  ? 371 SER A N   1 -0.291 0.031  0.027  
ATOM   2780  C  CA  . SER A 1 382 ? -33.074 3.014   10.367  1    98.97  ? 371 SER A CA  1 -0.303 0.028  0.026  
ATOM   2781  C  C   . SER A 1 382 ? -33.04  2.687   8.882   1    111.78 ? 371 SER A C   1 -0.303 0.025  0.022  
ATOM   2782  O  O   . SER A 1 382 ? -33.615 1.682   8.447   1    115.53 ? 371 SER A O   1 -0.308 0.015  0.021  
ATOM   2783  C  CB  . SER A 1 382 ? -34.042 4.165   10.625  1    105.17 ? 371 SER A CB  1 -0.312 0.038  0.027  
ATOM   2784  O  OG  . SER A 1 382 ? -33.939 4.684   11.948  1    105.05 ? 371 SER A OG  1 -0.311 0.043  0.03   
ATOM   2785  N  N   . ILE A 1 383 ? -32.371 3.539   8.089   1    108.39 ? 372 ILE A N   1 -0.297 0.032  0.02   
ATOM   2786  C  CA  . ILE A 1 383 ? -32.246 3.338   6.644   1    103.23 ? 372 ILE A CA  1 -0.296 0.031  0.017  
ATOM   2787  C  C   . ILE A 1 383 ? -31.777 1.921   6.344   1    105.03 ? 372 ILE A C   1 -0.291 0.018  0.016  
ATOM   2788  O  O   . ILE A 1 383 ? -32.419 1.172   5.599   1    106.05 ? 372 ILE A O   1 -0.297 0.011  0.014  
ATOM   2789  C  CB  . ILE A 1 383 ? -31.288 4.377   6.037   1    103.66 ? 372 ILE A CB  1 -0.287 0.04   0.015  
ATOM   2790  C  CG1 . ILE A 1 383 ? -31.926 5.767   6.049   1    100.68 ? 372 ILE A CG1 1 -0.293 0.053  0.015  
ATOM   2791  C  CG2 . ILE A 1 383 ? -30.874 3.983   4.629   1    99.82  ? 372 ILE A CG2 1 -0.283 0.037  0.012  
ATOM   2792  C  CD1 . ILE A 1 383 ? -33.184 5.842   5.22    1    103.43 ? 372 ILE A CD1 1 -0.304 0.054  0.013  
ATOM   2793  N  N   . PHE A 1 384 ? -30.657 1.526   6.951   1    104.87 ? 373 PHE A N   1 -0.281 0.014  0.017  
ATOM   2794  C  CA  . PHE A 1 384 ? -30.088 0.213   6.666   1    110.26 ? 373 PHE A CA  1 -0.276 0.002  0.017  
ATOM   2795  C  C   . PHE A 1 384 ? -30.984 -0.912  7.173   1    114.09 ? 373 PHE A C   1 -0.284 -0.008 0.018  
ATOM   2796  O  O   . PHE A 1 384 ? -31.014 -1.991  6.571   1    118.19 ? 373 PHE A O   1 -0.284 -0.018 0.016  
ATOM   2797  C  CB  . PHE A 1 384 ? -28.683 0.109   7.26    1    106.22 ? 373 PHE A CB  1 -0.263 0.001  0.018  
ATOM   2798  C  CG  . PHE A 1 384 ? -27.723 1.131   6.711   1    104.32 ? 373 PHE A CG  1 -0.254 0.01   0.017  
ATOM   2799  C  CD1 . PHE A 1 384 ? -28.005 1.811   5.543   1    103.36 ? 373 PHE A CD1 1 -0.257 0.017  0.014  
ATOM   2800  C  CD2 . PHE A 1 384 ? -26.546 1.422   7.369   1    107.6  ? 373 PHE A CD2 1 -0.243 0.013  0.018  
ATOM   2801  C  CE1 . PHE A 1 384 ? -27.13  2.759   5.032   1    102.6  ? 373 PHE A CE1 1 -0.249 0.025  0.013  
ATOM   2802  C  CE2 . PHE A 1 384 ? -25.666 2.373   6.863   1    108.5  ? 373 PHE A CE2 1 -0.235 0.022  0.017  
ATOM   2803  C  CZ  . PHE A 1 384 ? -25.965 3.042   5.688   1    104.76 ? 373 PHE A CZ  1 -0.238 0.028  0.014  
ATOM   2804  N  N   . THR A 1 385 ? -31.733 -0.677  8.252   1    108.79 ? 374 THR A N   1 -0.291 -0.006 0.021  
ATOM   2805  C  CA  . THR A 1 385 ? -32.704 -1.668  8.706   1    112.72 ? 374 THR A CA  1 -0.3   -0.015 0.022  
ATOM   2806  C  C   . THR A 1 385 ? -33.801 -1.883  7.657   1    110.7  ? 374 THR A C   1 -0.31  -0.017 0.019  
ATOM   2807  O  O   . THR A 1 385 ? -34.076 -3.024  7.267   1    115.03 ? 374 THR A O   1 -0.312 -0.028 0.018  
ATOM   2808  C  CB  . THR A 1 385 ? -33.287 -1.258  10.074  1    116.75 ? 374 THR A CB  1 -0.305 -0.012 0.025  
ATOM   2809  O  OG1 . THR A 1 385 ? -32.328 -1.516  11.117  1    110.36 ? 374 THR A OG1 1 -0.296 -0.014 0.028  
ATOM   2810  C  CG2 . THR A 1 385 ? -34.577 -2.028  10.384  1    116.95 ? 374 THR A CG2 1 -0.317 -0.019 0.026  
ATOM   2811  N  N   . LEU A 1 386 ? -34.431 -0.801  7.171   1    107.21 ? 375 LEU A N   1 -0.316 -0.007 0.018  
ATOM   2812  C  CA  . LEU A 1 386 ? -35.393 -0.938  6.071   1    113.35 ? 375 LEU A CA  1 -0.324 -0.009 0.015  
ATOM   2813  C  C   . LEU A 1 386 ? -34.789 -1.709  4.895   1    116.51 ? 375 LEU A C   1 -0.319 -0.016 0.012  
ATOM   2814  O  O   . LEU A 1 386 ? -35.455 -2.569  4.294   1    111.56 ? 375 LEU A O   1 -0.325 -0.024 0.011  
ATOM   2815  C  CB  . LEU A 1 386 ? -35.888 0.438   5.6     1    103.56 ? 375 LEU A CB  1 -0.329 0.004  0.014  
ATOM   2816  C  CG  . LEU A 1 386 ? -37.004 1.186   6.337   1    102.63 ? 375 LEU A CG  1 -0.339 0.011  0.016  
ATOM   2817  C  CD1 . LEU A 1 386 ? -38.165 0.269   6.687   1    106.21 ? 375 LEU A CD1 1 -0.35  0.002  0.017  
ATOM   2818  C  CD2 . LEU A 1 386 ? -36.461 1.827   7.588   1    116.15 ? 375 LEU A CD2 1 -0.334 0.017  0.019  
ATOM   2819  N  N   . TYR A 1 387 ? -33.528 -1.415  4.556   1    113.61 ? 376 TYR A N   1 -0.307 -0.013 0.011  
ATOM   2820  C  CA  . TYR A 1 387 ? -32.837 -2.138  3.492   1    115.94 ? 376 TYR A CA  1 -0.301 -0.02  0.009  
ATOM   2821  C  C   . TYR A 1 387 ? -32.752 -3.62   3.828   1    115.74 ? 376 TYR A C   1 -0.3   -0.033 0.01   
ATOM   2822  O  O   . TYR A 1 387 ? -33.35  -4.463  3.147   1    118.71 ? 376 TYR A O   1 -0.306 -0.041 0.008  
ATOM   2823  C  CB  . TYR A 1 387 ? -31.444 -1.527  3.278   1    118.52 ? 376 TYR A CB  1 -0.288 -0.014 0.008  
ATOM   2824  C  CG  . TYR A 1 387 ? -30.548 -2.186  2.24    1    116.23 ? 376 TYR A CG  1 -0.28  -0.02  0.006  
ATOM   2825  C  CD1 . TYR A 1 387 ? -31.07  -2.812  1.115   1    122.06 ? 376 TYR A CD1 1 -0.285 -0.026 0.003  
ATOM   2826  C  CD2 . TYR A 1 387 ? -29.17  -2.184  2.399   1    117.28 ? 376 TYR A CD2 1 -0.267 -0.02  0.006  
ATOM   2827  C  CE1 . TYR A 1 387 ? -30.236 -3.414  0.166   1    123.13 ? 376 TYR A CE1 1 -0.277 -0.031 0.0    
ATOM   2828  C  CE2 . TYR A 1 387 ? -28.334 -2.784  1.466   1    120.16 ? 376 TYR A CE2 1 -0.26  -0.026 0.004  
ATOM   2829  C  CZ  . TYR A 1 387 ? -28.867 -3.394  0.355   1    122.92 ? 376 TYR A CZ  1 -0.265 -0.031 0.001  
ATOM   2830  O  OH  . TYR A 1 387 ? -28.016 -3.986  -0.555  1    123.53 ? 376 TYR A OH  1 -0.257 -0.037 -0.001 
ATOM   2831  N  N   . ASN A 1 388 ? -32.044 -3.947  4.912   1    114.48 ? 377 ASN A N   1 -0.294 -0.036 0.012  
ATOM   2832  C  CA  . ASN A 1 388 ? -31.82  -5.341  5.281   1    115.72 ? 377 ASN A CA  1 -0.292 -0.049 0.013  
ATOM   2833  C  C   . ASN A 1 388 ? -33.121 -6.127  5.391   1    115.62 ? 377 ASN A C   1 -0.304 -0.056 0.013  
ATOM   2834  O  O   . ASN A 1 388 ? -33.18  -7.296  4.994   1    117.55 ? 377 ASN A O   1 -0.304 -0.067 0.012  
ATOM   2835  C  CB  . ASN A 1 388 ? -31.047 -5.408  6.594   1    119.96 ? 377 ASN A CB  1 -0.285 -0.05  0.016  
ATOM   2836  C  CG  . ASN A 1 388 ? -29.561 -5.206  6.401   1    120.07 ? 377 ASN A CG  1 -0.271 -0.048 0.016  
ATOM   2837  O  OD1 . ASN A 1 388 ? -29.032 -5.436  5.311   1    104.55 ? 377 ASN A OD1 1 -0.266 -0.05  0.013  
ATOM   2838  N  ND2 . ASN A 1 388 ? -28.87  -4.792  7.475   1    122.43 ? 377 ASN A ND2 1 -0.265 -0.044 0.019  
ATOM   2839  N  N   . GLU A 1 389 ? -34.177 -5.504  5.923   1    115.07 ? 378 GLU A N   1 -0.313 -0.05  0.015  
ATOM   2840  C  CA  . GLU A 1 389 ? -35.465 -6.18   6.038   1    118.51 ? 378 GLU A CA  1 -0.325 -0.057 0.015  
ATOM   2841  C  C   . GLU A 1 389 ? -36.251 -6.199  4.726   1    122.52 ? 378 GLU A C   1 -0.332 -0.057 0.012  
ATOM   2842  O  O   . GLU A 1 389 ? -37.26  -6.913  4.634   1    121.99 ? 378 GLU A O   1 -0.341 -0.063 0.012  
ATOM   2843  C  CB  . GLU A 1 389 ? -36.301 -5.539  7.161   1    111.08 ? 378 GLU A CB  1 -0.333 -0.051 0.018  
ATOM   2844  C  CG  . GLU A 1 389 ? -35.615 -5.639  8.534   1    120.68 ? 378 GLU A CG  1 -0.326 -0.052 0.021  
ATOM   2845  C  CD  . GLU A 1 389 ? -36.532 -5.368  9.732   1    123.77 ? 378 GLU A CD  1 -0.335 -0.049 0.024  
ATOM   2846  O  OE1 . GLU A 1 389 ? -37.492 -4.577  9.616   1    124.79 ? 378 GLU A OE1 1 -0.344 -0.042 0.024  
ATOM   2847  O  OE2 . GLU A 1 389 ? -36.278 -5.954  10.804  1    124.14 ? 378 GLU A OE2 1 -0.332 -0.055 0.027  
ATOM   2848  N  N   . ASN A 1 390 ? -35.812 -5.471  3.7     1    113.47 ? 379 ASN A N   1 -0.328 -0.05  0.009  
ATOM   2849  C  CA  . ASN A 1 390 ? -36.533 -5.462  2.436   1    118.89 ? 379 ASN A CA  1 -0.335 -0.05  0.006  
ATOM   2850  C  C   . ASN A 1 390 ? -35.566 -5.474  1.252   1    124.82 ? 379 ASN A C   1 -0.326 -0.05  0.003  
ATOM   2851  O  O   . ASN A 1 390 ? -35.717 -4.725  0.284   1    117.89 ? 379 ASN A O   1 -0.327 -0.043 0.001  
ATOM   2852  C  CB  . ASN A 1 390 ? -37.471 -4.266  2.385   1    120.29 ? 379 ASN A CB  1 -0.343 -0.039 0.006  
ATOM   2853  C  CG  . ASN A 1 390 ? -38.565 -4.351  3.417   1    114.61 ? 379 ASN A CG  1 -0.353 -0.04  0.009  
ATOM   2854  O  OD1 . ASN A 1 390 ? -39.349 -5.304  3.433   1    114.78 ? 379 ASN A OD1 1 -0.361 -0.049 0.009  
ATOM   2855  N  ND2 . ASN A 1 390 ? -38.619 -3.361  4.299   1    108.8  ? 379 ASN A ND2 1 -0.354 -0.031 0.011  
ATOM   2856  N  N   . LYS A 1 391 ? -34.573 -6.369  1.309   1    123.45 ? 380 LYS A N   1 -0.317 -0.058 0.003  
ATOM   2857  C  CA  . LYS A 1 391 ? -33.681 -6.572  0.173   1    121.19 ? 380 LYS A CA  1 -0.309 -0.06  0.0    
ATOM   2858  C  C   . LYS A 1 391 ? -34.398 -7.158  -1.043  1    126.74 ? 380 LYS A C   1 -0.315 -0.066 -0.003 
ATOM   2859  O  O   . LYS A 1 391 ? -33.804 -7.211  -2.131  1    122.66 ? 380 LYS A O   1 -0.31  -0.066 -0.005 
ATOM   2860  C  CB  . LYS A 1 391 ? -32.514 -7.469  0.584   1    116.63 ? 380 LYS A CB  1 -0.298 -0.068 0.001  
ATOM   2861  C  CG  . LYS A 1 391 ? -31.482 -6.774  1.448   1    116.91 ? 380 LYS A CG  1 -0.289 -0.062 0.004  
ATOM   2862  C  CD  . LYS A 1 391 ? -30.129 -7.482  1.36    1    124.59 ? 380 LYS A CD  1 -0.276 -0.069 0.003  
ATOM   2863  C  CE  . LYS A 1 391 ? -29.035 -6.744  2.145   1    119.32 ? 380 LYS A CE  1 -0.266 -0.062 0.005  
ATOM   2864  N  NZ  . LYS A 1 391 ? -27.719 -7.463  2.132   1    114.2  ? 380 LYS A NZ  1 -0.254 -0.068 0.005  
ATOM   2865  N  N   . ASP A 1 392 ? -35.653 -7.597  -0.883  1    128.8  ? 381 ASP A N   1 -0.327 -0.07  -0.002 
ATOM   2866  C  CA  . ASP A 1 392 ? -36.482 -8.023  -2.006  1    126.93 ? 381 ASP A CA  1 -0.334 -0.074 -0.005 
ATOM   2867  C  C   . ASP A 1 392 ? -37.098 -6.849  -2.754  1    123.31 ? 381 ASP A C   1 -0.34  -0.063 -0.007 
ATOM   2868  O  O   . ASP A 1 392 ? -37.49  -7.006  -3.911  1    120.29 ? 381 ASP A O   1 -0.344 -0.064 -0.01  
ATOM   2869  C  CB  . ASP A 1 392 ? -37.606 -8.955  -1.523  1    132.66 ? 381 ASP A CB  1 -0.345 -0.082 -0.004 
ATOM   2870  C  CG  . ASP A 1 392 ? -38.511 -8.307  -0.462  1    131.41 ? 381 ASP A CG  1 -0.353 -0.076 -0.001 
ATOM   2871  O  OD1 . ASP A 1 392 ? -37.977 -7.709  0.502   1    127.8  ? 381 ASP A OD1 1 -0.348 -0.071 0.001  
ATOM   2872  O  OD2 . ASP A 1 392 ? -39.758 -8.403  -0.595  1    128.47 ? 381 ASP A OD2 1 -0.364 -0.077 -0.001 
ATOM   2873  N  N   . CYS A 1 393 ? -37.19  -5.683  -2.119  1    129.95 ? 382 CYS A N   1 -0.341 -0.052 -0.005 
ATOM   2874  C  CA  . CYS A 1 393 ? -37.812 -4.505  -2.712  1    124.42 ? 382 CYS A CA  1 -0.347 -0.041 -0.007 
ATOM   2875  C  C   . CYS A 1 393 ? -36.813 -3.37   -2.896  1    119.2  ? 382 CYS A C   1 -0.337 -0.031 -0.007 
ATOM   2876  O  O   . CYS A 1 393 ? -36.626 -2.891  -4.017  1    115.09 ? 382 CYS A O   1 -0.336 -0.026 -0.01  
ATOM   2877  C  CB  . CYS A 1 393 ? -38.993 -4.075  -1.832  1    127.56 ? 382 CYS A CB  1 -0.357 -0.037 -0.005 
ATOM   2878  S  SG  . CYS A 1 393 ? -39.653 -2.458  -2.242  1    142.56 ? 382 CYS A SG  1 -0.363 -0.023 -0.006 
ATOM   2879  N  N   . VAL A 1 394 ? -36.163 -2.919  -1.818  1    127.78 ? 383 VAL A N   1 -0.331 -0.027 -0.005 
ATOM   2880  C  CA  . VAL A 1 394 ? -35.051 -1.988  -1.959  1    125.08 ? 383 VAL A CA  1 -0.321 -0.018 -0.005 
ATOM   2881  C  C   . VAL A 1 394 ? -33.955 -2.654  -2.772  1    121.38 ? 383 VAL A C   1 -0.311 -0.024 -0.007 
ATOM   2882  O  O   . VAL A 1 394 ? -33.503 -3.762  -2.454  1    123.18 ? 383 VAL A O   1 -0.307 -0.034 -0.006 
ATOM   2883  C  CB  . VAL A 1 394 ? -34.525 -1.546  -0.581  1    116.04 ? 383 VAL A CB  1 -0.316 -0.014 -0.001 
ATOM   2884  C  CG1 . VAL A 1 394 ? -33.141 -0.934  -0.735  1    118.24 ? 383 VAL A CG1 1 -0.304 -0.009 -0.002 
ATOM   2885  C  CG2 . VAL A 1 394 ? -35.466 -0.551  0.062   1    112.42 ? 383 VAL A CG2 1 -0.325 -0.005 0.0    
ATOM   2886  N  N   . ASP A 1 395 ? -33.522 -1.992  -3.836  1    118.12 ? 384 ASP A N   1 -0.307 -0.018 -0.01  
ATOM   2887  C  CA  . ASP A 1 395 ? -32.476 -2.61   -4.636  1    125.89 ? 384 ASP A CA  1 -0.298 -0.024 -0.012 
ATOM   2888  C  C   . ASP A 1 395 ? -31.097 -2.052  -4.31   1    126.38 ? 384 ASP A C   1 -0.285 -0.019 -0.011 
ATOM   2889  O  O   . ASP A 1 395 ? -30.362 -2.643  -3.519  1    128.49 ? 384 ASP A O   1 -0.278 -0.024 -0.009 
ATOM   2890  C  CB  . ASP A 1 395 ? -32.771 -2.459  -6.122  1    128.16 ? 384 ASP A CB  1 -0.3   -0.023 -0.015 
ATOM   2891  C  CG  . ASP A 1 395 ? -32.212 -3.606  -6.915  1    131.72 ? 384 ASP A CG  1 -0.295 -0.033 -0.017 
ATOM   2892  O  OD1 . ASP A 1 395 ? -31.123 -4.093  -6.509  1    131.52 ? 384 ASP A OD1 1 -0.285 -0.038 -0.016 
ATOM   2893  O  OD2 . ASP A 1 395 ? -32.869 -4.035  -7.895  1    127.29 ? 384 ASP A OD2 1 -0.301 -0.037 -0.02  
ATOM   2894  N  N   . THR A 1 396 ? -30.725 -0.932  -4.914  1    123.6  ? 385 THR A N   1 -0.282 -0.009 -0.012 
ATOM   2895  C  CA  . THR A 1 396 ? -29.434 -0.324  -4.644  1    116.95 ? 385 THR A CA  1 -0.27  -0.003 -0.012 
ATOM   2896  C  C   . THR A 1 396 ? -29.577 0.824   -3.653  1    110.3  ? 385 THR A C   1 -0.271 0.008  -0.009 
ATOM   2897  O  O   . THR A 1 396 ? -30.635 1.448   -3.544  1    107.85 ? 385 THR A O   1 -0.281 0.013  -0.009 
ATOM   2898  C  CB  . THR A 1 396 ? -28.787 0.176   -5.94   1    120.29 ? 385 THR A CB  1 -0.264 0.002  -0.015 
ATOM   2899  O  OG1 . THR A 1 396 ? -29.745 0.935   -6.698  1    123.43 ? 385 THR A OG1 1 -0.273 0.009  -0.017 
ATOM   2900  C  CG2 . THR A 1 396 ? -28.296 -1.011  -6.773  1    117.74 ? 385 THR A CG2 1 -0.259 -0.009 -0.017 
ATOM   2901  N  N   . ILE A 1 397 ? -28.501 1.067   -2.903  1    113.77 ? 386 ILE A N   1 -0.261 0.01   -0.007 
ATOM   2902  C  CA  . ILE A 1 397 ? -28.327 2.262   -2.083  1    106.32 ? 386 ILE A CA  1 -0.26  0.021  -0.005 
ATOM   2903  C  C   . ILE A 1 397 ? -27.074 2.979   -2.575  1    103.84 ? 386 ILE A C   1 -0.248 0.027  -0.006 
ATOM   2904  O  O   . ILE A 1 397 ? -26.016 2.354   -2.738  1    104.22 ? 386 ILE A O   1 -0.238 0.022  -0.007 
ATOM   2905  C  CB  . ILE A 1 397 ? -28.208 1.924   -0.581  1    104.91 ? 386 ILE A CB  1 -0.259 0.018  -0.001 
ATOM   2906  C  CG1 . ILE A 1 397 ? -29.588 1.654   0.022   1    110.82 ? 386 ILE A CG1 1 -0.271 0.015  0.0    
ATOM   2907  C  CG2 . ILE A 1 397 ? -27.491 3.05    0.18    1    102    ? 386 ILE A CG2 1 -0.252 0.028  0.0    
ATOM   2908  C  CD1 . ILE A 1 397 ? -29.624 1.723   1.555   1    108.9  ? 386 ILE A CD1 1 -0.271 0.016  0.004  
ATOM   2909  N  N   . TYR A 1 398 ? -27.192 4.277   -2.84   1    94.15  ? 387 TYR A N   1 -0.249 0.039  -0.007 
ATOM   2910  C  CA  . TYR A 1 398 ? -26.024 5.082   -3.165  1    95.38  ? 387 TYR A CA  1 -0.238 0.047  -0.008 
ATOM   2911  C  C   . TYR A 1 398 ? -26.016 6.31    -2.282  1    100.88 ? 387 TYR A C   1 -0.238 0.058  -0.006 
ATOM   2912  O  O   . TYR A 1 398 ? -26.941 7.127   -2.35   1    101.63 ? 387 TYR A O   1 -0.247 0.065  -0.006 
ATOM   2913  C  CB  . TYR A 1 398 ? -25.994 5.505   -4.62   1    98.06  ? 387 TYR A CB  1 -0.238 0.05   -0.012 
ATOM   2914  C  CG  . TYR A 1 398 ? -24.906 6.522   -4.907  1    97.47  ? 387 TYR A CG  1 -0.228 0.06   -0.012 
ATOM   2915  C  CD1 . TYR A 1 398 ? -23.588 6.117   -5.141  1    95.19  ? 387 TYR A CD1 1 -0.216 0.056  -0.013 
ATOM   2916  C  CD2 . TYR A 1 398 ? -25.193 7.886   -4.946  1    98.56  ? 387 TYR A CD2 1 -0.231 0.072  -0.012 
ATOM   2917  C  CE1 . TYR A 1 398 ? -22.584 7.041   -5.422  1    94.27  ? 387 TYR A CE1 1 -0.207 0.065  -0.014 
ATOM   2918  C  CE2 . TYR A 1 398 ? -24.201 8.821   -5.22   1    102.01 ? 387 TYR A CE2 1 -0.222 0.081  -0.013 
ATOM   2919  C  CZ  . TYR A 1 398 ? -22.898 8.392   -5.467  1    100.43 ? 387 TYR A CZ  1 -0.21  0.077  -0.014 
ATOM   2920  O  OH  . TYR A 1 398 ? -21.912 9.319   -5.751  1    97.72  ? 387 TYR A OH  1 -0.201 0.085  -0.014 
ATOM   2921  N  N   . TRP A 1 399 ? -24.966 6.43    -1.472  1    103.82 ? 388 TRP A N   1 -0.229 0.059  -0.004 
ATOM   2922  C  CA  . TRP A 1 399 ? -24.706 7.562   -0.598  1    98.08  ? 388 TRP A CA  1 -0.226 0.069  -0.001 
ATOM   2923  C  C   . TRP A 1 399 ? -23.515 8.302   -1.186  1    98.05  ? 388 TRP A C   1 -0.215 0.076  -0.003 
ATOM   2924  O  O   . TRP A 1 399 ? -22.518 7.67    -1.58   1    92.7   ? 388 TRP A O   1 -0.206 0.07   -0.004 
ATOM   2925  C  CB  . TRP A 1 399 ? -24.434 7.06    0.825   1    102.23 ? 388 TRP A CB  1 -0.224 0.065  0.002  
ATOM   2926  C  CG  . TRP A 1 399 ? -24.123 8.069   1.916   1    102.16 ? 388 TRP A CG  1 -0.221 0.074  0.005  
ATOM   2927  C  CD1 . TRP A 1 399 ? -24.933 8.412   2.969   1    99     ? 388 TRP A CD1 1 -0.228 0.077  0.007  
ATOM   2928  C  CD2 . TRP A 1 399 ? -22.906 8.807   2.096   1    97.15  ? 388 TRP A CD2 1 -0.21  0.081  0.005  
ATOM   2929  N  NE1 . TRP A 1 399 ? -24.307 9.338   3.769   1    98.1   ? 388 TRP A NE1 1 -0.223 0.086  0.009  
ATOM   2930  C  CE2 . TRP A 1 399 ? -23.061 9.593   3.257   1    98.76  ? 388 TRP A CE2 1 -0.211 0.088  0.008  
ATOM   2931  C  CE3 . TRP A 1 399 ? -21.703 8.886   1.386   1    93.2   ? 388 TRP A CE3 1 -0.199 0.081  0.003  
ATOM   2932  C  CZ2 . TRP A 1 399 ? -22.054 10.443  3.721   1    98.18  ? 388 TRP A CZ2 1 -0.202 0.096  0.009  
ATOM   2933  C  CZ3 . TRP A 1 399 ? -20.71  9.734   1.845   1    93.11  ? 388 TRP A CZ3 1 -0.19  0.089  0.005  
ATOM   2934  C  CH2 . TRP A 1 399 ? -20.888 10.5    2.998   1    93.71  ? 388 TRP A CH2 1 -0.191 0.096  0.007  
ATOM   2935  N  N   . GLY A 1 400 ? -23.641 9.617   -1.294  1    97.25  ? 389 GLY A N   1 -0.217 0.088  -0.003 
ATOM   2936  C  CA  . GLY A 1 400 ? -22.607 10.443  -1.913  1    94.65  ? 389 GLY A CA  1 -0.207 0.096  -0.005 
ATOM   2937  C  C   . GLY A 1 400 ? -22.388 11.726  -1.141  1    94.02  ? 389 GLY A C   1 -0.205 0.107  -0.003 
ATOM   2938  O  O   . GLY A 1 400 ? -23.326 12.408  -0.764  1    96.68  ? 389 GLY A O   1 -0.214 0.114  -0.002 
ATOM   2939  N  N   . LEU A 1 401 ? -21.105 12.052  -0.938  1    89.6   ? 390 LEU A N   1 -0.193 0.11   -0.002 
ATOM   2940  C  CA  . LEU A 1 401 ? -20.69  13.158  -0.071  1    94.81  ? 390 LEU A CA  1 -0.19  0.121  -0.0   
ATOM   2941  C  C   . LEU A 1 401 ? -20.966 14.523  -0.698  1    96.01  ? 390 LEU A C   1 -0.192 0.133  -0.002 
ATOM   2942  O  O   . LEU A 1 401 ? -20.374 14.863  -1.725  1    99.38  ? 390 LEU A O   1 -0.187 0.136  -0.004 
ATOM   2943  C  CB  . LEU A 1 401 ? -19.202 13.013  0.223   1    99.15  ? 390 LEU A CB  1 -0.176 0.119  0.001  
ATOM   2944  C  CG  . LEU A 1 401 ? -18.567 14.205  0.927   1    100.9  ? 390 LEU A CG  1 -0.17  0.13   0.002  
ATOM   2945  C  CD1 . LEU A 1 401 ? -17.718 13.66   2.005   1    96.76  ? 390 LEU A CD1 1 -0.162 0.125  0.005  
ATOM   2946  C  CD2 . LEU A 1 401 ? -17.731 15.032  -0.052  1    107    ? 390 LEU A CD2 1 -0.162 0.138  -0.0   
ATOM   2947  N  N   . GLU A 1 402 ? -21.791 15.349  -0.035  1    96.01  ? 391 GLU A N   1 -0.2   0.141  -0.0   
ATOM   2948  C  CA  . GLU A 1 402 ? -22.07  16.694  -0.526  1    89.78  ? 391 GLU A CA  1 -0.202 0.153  -0.001 
ATOM   2949  C  C   . GLU A 1 402 ? -21.364 17.68   0.34    1    90.03  ? 391 GLU A C   1 -0.196 0.162  0.001  
ATOM   2950  O  O   . GLU A 1 402 ? -20.149 17.93   0.155   1    93.13  ? 391 GLU A O   1 -0.185 0.164  0.0    
ATOM   2951  C  CB  . GLU A 1 402 ? -23.592 16.881  -0.661  1    91.45  ? 391 GLU A CB  1 -0.216 0.155  -0.002 
ATOM   2952  C  CG  . GLU A 1 402 ? -24.205 15.947  -1.73   1    95.76  ? 391 GLU A CG  1 -0.222 0.146  -0.004 
ATOM   2953  C  CD  . GLU A 1 402 ? -23.678 16.223  -3.163  1    104    ? 391 GLU A CD  1 -0.217 0.149  -0.008 
ATOM   2954  O  OE1 . GLU A 1 402 ? -24.208 17.141  -3.845  1    101.18 ? 391 GLU A OE1 1 -0.222 0.157  -0.01  
ATOM   2955  O  OE2 . GLU A 1 402 ? -22.726 15.52   -3.598  1    103.26 ? 391 GLU A OE2 1 -0.208 0.142  -0.009 
ATOM   2956  N  N   . GLY A 1 403 ? -22.014 18.308  1.334   1    102.16 ? 392 GLY A N   1 -0.202 0.168  0.003  
ATOM   2957  C  CA  . GLY A 1 403 ? -21.376 19.245  2.235   1    103.79 ? 392 GLY A CA  1 -0.196 0.176  0.006  
ATOM   2958  C  C   . GLY A 1 403 ? -20.919 18.636  3.562   1    99.15  ? 392 GLY A C   1 -0.192 0.171  0.009  
ATOM   2959  O  O   . GLY A 1 403 ? -20.869 17.419  3.751   1    94.31  ? 392 GLY A O   1 -0.191 0.16   0.009  
ATOM   2960  N  N   . GLY A 1 404 ? -20.609 19.527  4.511   1    102.81 ? 393 GLY A N   1 -0.189 0.179  0.011  
ATOM   2961  C  CA  . GLY A 1 404 ? -19.951 19.186  5.768   1    96.2   ? 393 GLY A CA  1 -0.183 0.176  0.014  
ATOM   2962  C  C   . GLY A 1 404 ? -18.488 19.585  5.757   1    94.41  ? 393 GLY A C   1 -0.169 0.179  0.014  
ATOM   2963  O  O   . GLY A 1 404 ? -17.659 18.869  5.176   1    91.83  ? 393 GLY A O   1 -0.162 0.173  0.013  
ATOM   2964  N  N   . TYR A 1 405 ? -18.148 20.72   6.401   1    96.25  ? 394 TYR A N   1 -0.166 0.19   0.016  
ATOM   2965  C  CA  . TYR A 1 405 ? -16.877 21.4    6.158   1    102.82 ? 394 TYR A CA  1 -0.155 0.196  0.015  
ATOM   2966  C  C   . TYR A 1 405 ? -15.925 21.506  7.367   1    102.47 ? 394 TYR A C   1 -0.146 0.197  0.018  
ATOM   2967  O  O   . TYR A 1 405 ? -14.709 21.511  7.16    1    105.28 ? 394 TYR A O   1 -0.135 0.197  0.018  
ATOM   2968  C  CB  . TYR A 1 405 ? -17.159 22.796  5.553   1    98.85  ? 394 TYR A CB  1 -0.157 0.209  0.014  
ATOM   2969  C  CG  . TYR A 1 405 ? -17.786 22.662  4.174   1    111.79 ? 394 TYR A CG  1 -0.163 0.208  0.01   
ATOM   2970  C  CD1 . TYR A 1 405 ? -19.088 22.175  4.019   1    113.33 ? 394 TYR A CD1 1 -0.175 0.203  0.01   
ATOM   2971  C  CD2 . TYR A 1 405 ? -17.067 22.971  3.019   1    111.23 ? 394 TYR A CD2 1 -0.156 0.211  0.008  
ATOM   2972  C  CE1 . TYR A 1 405 ? -19.65  22.003  2.754   1    109.79 ? 394 TYR A CE1 1 -0.18  0.202  0.007  
ATOM   2973  C  CE2 . TYR A 1 405 ? -17.633 22.804  1.767   1    101.86 ? 394 TYR A CE2 1 -0.162 0.209  0.004  
ATOM   2974  C  CZ  . TYR A 1 405 ? -18.931 22.319  1.64    1    104.99 ? 394 TYR A CZ  1 -0.173 0.205  0.004  
ATOM   2975  O  OH  . TYR A 1 405 ? -19.553 22.129  0.411   1    110.53 ? 394 TYR A OH  1 -0.179 0.203  0.001  
ATOM   2976  N  N   . ASP A 1 406 ? -16.411 21.56   8.603   1    95.8   ? 395 ASP A N   1 -0.15  0.198  0.021  
ATOM   2977  C  CA  . ASP A 1 406 ? -15.509 21.709  9.753   1    103.51 ? 395 ASP A CA  1 -0.142 0.199  0.024  
ATOM   2978  C  C   . ASP A 1 406 ? -14.771 20.397  10.058  1    100.06 ? 395 ASP A C   1 -0.135 0.187  0.025  
ATOM   2979  O  O   . ASP A 1 406 ? -15.402 19.345  10.211  1    98.64  ? 395 ASP A O   1 -0.141 0.177  0.025  
ATOM   2980  C  CB  . ASP A 1 406 ? -16.304 22.171  10.98   1    108.79 ? 395 ASP A CB  1 -0.149 0.203  0.027  
ATOM   2981  C  CG  . ASP A 1 406 ? -15.418 22.483  12.187  1    109.12 ? 395 ASP A CG  1 -0.141 0.206  0.03   
ATOM   2982  O  OD1 . ASP A 1 406 ? -14.791 23.579  12.197  1    111.54 ? 395 ASP A OD1 1 -0.136 0.216  0.03   
ATOM   2983  O  OD2 . ASP A 1 406 ? -15.381 21.65   13.13   1    98.14  ? 395 ASP A OD2 1 -0.141 0.198  0.033  
ATOM   2984  N  N   . ARG A 1 407 ? -13.436 20.47   10.192  1    95.63  ? 396 ARG A N   1 -0.123 0.188  0.025  
ATOM   2985  C  CA  . ARG A 1 407 ? -12.612 19.254  10.192  1    95.48  ? 396 ARG A CA  1 -0.116 0.176  0.025  
ATOM   2986  C  C   . ARG A 1 407 ? -12.955 18.32   11.355  1    98.09  ? 396 ARG A C   1 -0.119 0.168  0.028  
ATOM   2987  O  O   . ARG A 1 407 ? -13.167 17.116  11.155  1    91.87  ? 396 ARG A O   1 -0.121 0.157  0.028  
ATOM   2988  C  CB  . ARG A 1 407 ? -11.124 19.616  10.212  1    97.99  ? 396 ARG A CB  1 -0.102 0.18   0.025  
ATOM   2989  C  CG  . ARG A 1 407 ? -10.198 18.534  10.792  1    92.63  ? 396 ARG A CG  1 -0.093 0.17   0.027  
ATOM   2990  C  CD  . ARG A 1 407 ? -9.818  17.515  9.759   1    93.89  ? 396 ARG A CD  1 -0.09  0.161  0.024  
ATOM   2991  N  NE  . ARG A 1 407 ? -8.542  16.851  10.009  1    95.33  ? 396 ARG A NE  1 -0.078 0.154  0.025  
ATOM   2992  C  CZ  . ARG A 1 407 ? -7.348  17.418  9.856   1    97.11  ? 396 ARG A CZ  1 -0.067 0.16   0.025  
ATOM   2993  N  NH1 . ARG A 1 407 ? -7.222  18.715  9.605   1    91.81  ? 396 ARG A NH1 1 -0.066 0.172  0.024  
ATOM   2994  N  NH2 . ARG A 1 407 ? -6.252  16.665  9.964   1    92.85  ? 396 ARG A NH2 1 -0.057 0.153  0.025  
ATOM   2995  N  N   . THR A 1 408 ? -12.997 18.841  12.586  1    105.38 ? 397 THR A N   1 -0.119 0.173  0.031  
ATOM   2996  C  CA  . THR A 1 408 ? -13.262 17.932  13.695  1    102.22 ? 397 THR A CA  1 -0.122 0.164  0.034  
ATOM   2997  C  C   . THR A 1 408 ? -14.714 17.483  13.729  1    99.91  ? 397 THR A C   1 -0.135 0.16   0.034  
ATOM   2998  O  O   . THR A 1 408 ? -14.996 16.394  14.248  1    102.15 ? 397 THR A O   1 -0.137 0.15   0.036  
ATOM   2999  C  CB  . THR A 1 408 ? -12.876 18.545  15.047  1    100.09 ? 397 THR A CB  1 -0.118 0.17   0.038  
ATOM   3000  O  OG1 . THR A 1 408 ? -13.591 19.772  15.247  1    106.59 ? 397 THR A OG1 1 -0.125 0.181  0.038  
ATOM   3001  C  CG2 . THR A 1 408 ? -11.357 18.792  15.122  1    91.18  ? 397 THR A CG2 1 -0.104 0.172  0.038  
ATOM   3002  N  N   . MET A 1 409 ? -15.638 18.272  13.174  1    94.87  ? 398 MET A N   1 -0.143 0.167  0.033  
ATOM   3003  C  CA  . MET A 1 409 ? -17.017 17.803  13.066  1    95.35  ? 398 MET A CA  1 -0.156 0.163  0.033  
ATOM   3004  C  C   . MET A 1 409 ? -17.126 16.653  12.057  1    99.61  ? 398 MET A C   1 -0.157 0.153  0.03   
ATOM   3005  O  O   . MET A 1 409 ? -17.571 15.547  12.394  1    97.08  ? 398 MET A O   1 -0.161 0.142  0.031  
ATOM   3006  C  CB  . MET A 1 409 ? -17.953 18.961  12.703  1    89.95  ? 398 MET A CB  1 -0.165 0.174  0.032  
ATOM   3007  C  CG  . MET A 1 409 ? -19.443 18.588  12.728  1    99.18  ? 398 MET A CG  1 -0.178 0.17   0.032  
ATOM   3008  S  SD  . MET A 1 409 ? -20.045 17.709  11.245  1    96.9   ? 398 MET A SD  1 -0.184 0.162  0.028  
ATOM   3009  C  CE  . MET A 1 409 ? -19.962 19.03   10.027  1    95.23  ? 398 MET A CE  1 -0.183 0.174  0.025  
ATOM   3010  N  N   . TYR A 1 410 ? -16.699 16.877  10.814  1    99.73  ? 399 TYR A N   1 -0.153 0.155  0.027  
ATOM   3011  C  CA  . TYR A 1 410 ? -16.918 15.823  9.83    1    102.22 ? 399 TYR A CA  1 -0.155 0.145  0.025  
ATOM   3012  C  C   . TYR A 1 410 ? -16.085 14.57   10.105  1    100.56 ? 399 TYR A C   1 -0.147 0.134  0.025  
ATOM   3013  O  O   . TYR A 1 410 ? -16.465 13.479  9.653   1    95.8   ? 399 TYR A O   1 -0.151 0.124  0.024  
ATOM   3014  C  CB  . TYR A 1 410 ? -16.687 16.338  8.399   1    86.58  ? 399 TYR A CB  1 -0.153 0.15   0.021  
ATOM   3015  C  CG  . TYR A 1 410 ? -15.276 16.724  7.989   1    88.3   ? 399 TYR A CG  1 -0.14  0.153  0.02   
ATOM   3016  C  CD1 . TYR A 1 410 ? -14.267 15.773  7.88    1    83.94  ? 399 TYR A CD1 1 -0.131 0.145  0.02   
ATOM   3017  C  CD2 . TYR A 1 410 ? -14.979 18.032  7.622   1    92.19  ? 399 TYR A CD2 1 -0.137 0.165  0.019  
ATOM   3018  C  CE1 . TYR A 1 410 ? -12.985 16.125  7.473   1    86.95  ? 399 TYR A CE1 1 -0.119 0.148  0.019  
ATOM   3019  C  CE2 . TYR A 1 410 ? -13.71  18.389  7.204   1    93.01  ? 399 TYR A CE2 1 -0.126 0.169  0.018  
ATOM   3020  C  CZ  . TYR A 1 410 ? -12.712 17.433  7.135   1    90.97  ? 399 TYR A CZ  1 -0.116 0.16   0.018  
ATOM   3021  O  OH  . TYR A 1 410 ? -11.442 17.783  6.714   1    92.74  ? 399 TYR A OH  1 -0.105 0.163  0.017  
ATOM   3022  N  N   . GLU A 1 411 ? -14.975 14.677  10.845  1    98.21  ? 400 GLU A N   1 -0.137 0.135  0.027  
ATOM   3023  C  CA  . GLU A 1 411 ? -14.263 13.445  11.164  1    93.89  ? 400 GLU A CA  1 -0.131 0.123  0.028  
ATOM   3024  C  C   . GLU A 1 411 ? -15.047 12.621  12.17   1    95.73  ? 400 GLU A C   1 -0.138 0.116  0.03   
ATOM   3025  O  O   . GLU A 1 411 ? -15.067 11.389  12.075  1    93.19  ? 400 GLU A O   1 -0.138 0.104  0.03   
ATOM   3026  C  CB  . GLU A 1 411 ? -12.857 13.747  11.661  1    89.64  ? 400 GLU A CB  1 -0.118 0.126  0.029  
ATOM   3027  C  CG  . GLU A 1 411 ? -11.987 14.336  10.591  1    94.92  ? 400 GLU A CG  1 -0.11  0.131  0.026  
ATOM   3028  C  CD  . GLU A 1 411 ? -10.501 14.274  10.901  1    104.35 ? 400 GLU A CD  1 -0.096 0.131  0.027  
ATOM   3029  O  OE1 . GLU A 1 411 ? -10.122 14.442  12.091  1    108.82 ? 400 GLU A OE1 1 -0.093 0.132  0.03   
ATOM   3030  O  OE2 . GLU A 1 411 ? -9.71   14.054  9.942   1    105.13 ? 400 GLU A OE2 1 -0.089 0.129  0.025  
ATOM   3031  N  N   . ARG A 1 412 ? -15.74  13.279  13.106  1    95.56  ? 401 ARG A N   1 -0.144 0.122  0.033  
ATOM   3032  C  CA  . ARG A 1 412 ? -16.572 12.531  14.045  1    103.18 ? 401 ARG A CA  1 -0.152 0.115  0.035  
ATOM   3033  C  C   . ARG A 1 412 ? -17.794 11.947  13.354  1    100.21 ? 401 ARG A C   1 -0.163 0.109  0.033  
ATOM   3034  O  O   . ARG A 1 412 ? -18.158 10.787  13.599  1    99.65  ? 401 ARG A O   1 -0.166 0.099  0.034  
ATOM   3035  C  CB  . ARG A 1 412 ? -17.014 13.404  15.227  1    98.45  ? 401 ARG A CB  1 -0.156 0.123  0.038  
ATOM   3036  C  CG  . ARG A 1 412 ? -18.024 12.682  16.155  1    105.66 ? 401 ARG A CG  1 -0.165 0.116  0.04   
ATOM   3037  C  CD  . ARG A 1 412 ? -18.336 13.416  17.509  1    102.75 ? 401 ARG A CD  1 -0.168 0.123  0.044  
ATOM   3038  N  NE  . ARG A 1 412 ? -19.232 14.571  17.401  1    93.1   ? 401 ARG A NE  1 -0.176 0.134  0.043  
ATOM   3039  C  CZ  . ARG A 1 412 ? -18.828 15.82   17.195  1    99.5   ? 401 ARG A CZ  1 -0.173 0.145  0.043  
ATOM   3040  N  NH1 . ARG A 1 412 ? -17.543 16.132  17.122  1    97.88  ? 401 ARG A NH1 1 -0.161 0.148  0.043  
ATOM   3041  N  NH2 . ARG A 1 412 ? -19.735 16.779  17.033  1    99.98  ? 401 ARG A NH2 1 -0.181 0.154  0.043  
ATOM   3042  N  N   . GLU A 1 413 ? -18.464 12.74   12.509  1    101.87 ? 402 GLU A N   1 -0.169 0.117  0.031  
ATOM   3043  C  CA  . GLU A 1 413 ? -19.648 12.214  11.835  1    97.42  ? 402 GLU A CA  1 -0.18  0.112  0.03   
ATOM   3044  C  C   . GLU A 1 413 ? -19.296 11.029  10.965  1    91.62  ? 402 GLU A C   1 -0.177 0.101  0.027  
ATOM   3045  O  O   . GLU A 1 413 ? -20.068 10.066  10.881  1    88.59  ? 402 GLU A O   1 -0.184 0.092  0.027  
ATOM   3046  C  CB  . GLU A 1 413 ? -20.349 13.288  10.999  1    93.79  ? 402 GLU A CB  1 -0.186 0.122  0.027  
ATOM   3047  C  CG  . GLU A 1 413 ? -20.963 14.466  11.769  1    102.21 ? 402 GLU A CG  1 -0.192 0.133  0.029  
ATOM   3048  C  CD  . GLU A 1 413 ? -21.499 14.098  13.138  1    102.76 ? 402 GLU A CD  1 -0.197 0.129  0.033  
ATOM   3049  O  OE1 . GLU A 1 413 ? -21.326 14.921  14.089  1    101.56 ? 402 GLU A OE1 1 -0.195 0.137  0.035  
ATOM   3050  O  OE2 . GLU A 1 413 ? -22.1   12.996  13.234  1    104.84 ? 402 GLU A OE2 1 -0.203 0.119  0.033  
ATOM   3051  N  N   . LEU A 1 414 ? -18.114 11.067  10.325  1    90.88  ? 403 LEU A N   1 -0.166 0.101  0.026  
ATOM   3052  C  CA  . LEU A 1 414 ? -17.694 9.955   9.468   1    92.89  ? 403 LEU A CA  1 -0.162 0.091  0.024  
ATOM   3053  C  C   . LEU A 1 414 ? -17.514 8.673   10.271  1    98     ? 403 LEU A C   1 -0.161 0.079  0.026  
ATOM   3054  O  O   . LEU A 1 414 ? -17.924 7.587   9.832   1    92.83  ? 403 LEU A O   1 -0.164 0.07   0.025  
ATOM   3055  C  CB  . LEU A 1 414 ? -16.388 10.276  8.745   1    94.25  ? 403 LEU A CB  1 -0.15  0.094  0.022  
ATOM   3056  C  CG  . LEU A 1 414 ? -16.113 9.302   7.591   1    91.21  ? 403 LEU A CG  1 -0.148 0.085  0.019  
ATOM   3057  C  CD1 . LEU A 1 414 ? -17.319 9.317   6.691   1    93.04  ? 403 LEU A CD1 1 -0.159 0.085  0.017  
ATOM   3058  C  CD2 . LEU A 1 414 ? -14.832 9.607   6.828   1    89.77  ? 403 LEU A CD2 1 -0.136 0.088  0.017  
ATOM   3059  N  N   . LYS A 1 415 ? -16.845 8.784   11.437  1    102.01 ? 404 LYS A N   1 -0.154 0.08   0.029  
ATOM   3060  C  CA  . LYS A 1 415 ? -16.637 7.636   12.315  1    92.66  ? 404 LYS A CA  1 -0.152 0.07   0.031  
ATOM   3061  C  C   . LYS A 1 415 ? -17.97  7.013   12.692  1    93.95  ? 404 LYS A C   1 -0.165 0.064  0.032  
ATOM   3062  O  O   . LYS A 1 415 ? -18.11  5.784   12.669  1    94.69  ? 404 LYS A O   1 -0.166 0.053  0.032  
ATOM   3063  C  CB  . LYS A 1 415 ? -15.834 8.055   13.56   1    97.02  ? 404 LYS A CB  1 -0.145 0.074  0.034  
ATOM   3064  C  CG  . LYS A 1 415 ? -15.338 6.891   14.438  1    105.62 ? 404 LYS A CG  1 -0.141 0.063  0.036  
ATOM   3065  C  CD  . LYS A 1 415 ? -14.347 7.353   15.509  1    109.91 ? 404 LYS A CD  1 -0.131 0.067  0.039  
ATOM   3066  C  CE  . LYS A 1 415 ? -14.055 6.237   16.523  1    117.7  ? 404 LYS A CE  1 -0.129 0.057  0.041  
ATOM   3067  N  NZ  . LYS A 1 415 ? -12.893 6.528   17.413  1    110.74 ? 404 LYS A NZ  1 -0.118 0.06   0.043  
ATOM   3068  N  N   . ILE A 1 416 ? -18.972 7.848   13.001  1    90.03  ? 405 ILE A N   1 -0.174 0.072  0.032  
ATOM   3069  C  CA  . ILE A 1 416 ? -20.338 7.352   13.16   1    92.09  ? 405 ILE A CA  1 -0.186 0.067  0.033  
ATOM   3070  C  C   . ILE A 1 416 ? -20.761 6.581   11.914  1    97.88  ? 405 ILE A C   1 -0.19  0.06   0.03   
ATOM   3071  O  O   . ILE A 1 416 ? -21.149 5.409   11.988  1    96.01  ? 405 ILE A O   1 -0.194 0.05   0.03   
ATOM   3072  C  CB  . ILE A 1 416 ? -21.32  8.502   13.443  1    93.5   ? 405 ILE A CB  1 -0.195 0.078  0.034  
ATOM   3073  C  CG1 . ILE A 1 416 ? -21.135 9.073   14.846  1    98.53  ? 405 ILE A CG1 1 -0.194 0.083  0.037  
ATOM   3074  C  CG2 . ILE A 1 416 ? -22.788 8.02    13.234  1    85.35  ? 405 ILE A CG2 1 -0.209 0.073  0.033  
ATOM   3075  C  CD1 . ILE A 1 416 ? -22.115 10.17   15.111  1    100.13 ? 405 ILE A CD1 1 -0.203 0.093  0.038  
ATOM   3076  N  N   . LEU A 1 417 ? -20.702 7.246   10.747  1    100.47 ? 406 LEU A N   1 -0.19  0.066  0.027  
ATOM   3077  C  CA  . LEU A 1 417 ? -21.15  6.634   9.499   1    96.38  ? 406 LEU A CA  1 -0.194 0.061  0.024  
ATOM   3078  C  C   . LEU A 1 417 ? -20.425 5.313   9.227   1    100.21 ? 406 LEU A C   1 -0.187 0.049  0.023  
ATOM   3079  O  O   . LEU A 1 417 ? -21.065 4.322   8.857   1    102.99 ? 406 LEU A O   1 -0.193 0.04   0.022  
ATOM   3080  C  CB  . LEU A 1 417 ? -20.962 7.614   8.33    1    100.29 ? 406 LEU A CB  1 -0.192 0.07   0.021  
ATOM   3081  C  CG  . LEU A 1 417 ? -21.712 7.397   6.996   1    99.31  ? 406 LEU A CG  1 -0.199 0.068  0.017  
ATOM   3082  C  CD1 . LEU A 1 417 ? -21.053 6.311   6.164   1    98.85  ? 406 LEU A CD1 1 -0.193 0.058  0.015  
ATOM   3083  C  CD2 . LEU A 1 417 ? -23.205 7.101   7.203   1    97.2   ? 406 LEU A CD2 1 -0.213 0.065  0.018  
ATOM   3084  N  N   . LEU A 1 418 ? -19.097 5.271   9.409   1    95.65  ? 407 LEU A N   1 -0.175 0.048  0.023  
ATOM   3085  C  CA  . LEU A 1 418 ? -18.373 4.025   9.151   1    99.02  ? 407 LEU A CA  1 -0.168 0.037  0.023  
ATOM   3086  C  C   . LEU A 1 418 ? -18.783 2.924   10.124  1    106.11 ? 407 LEU A C   1 -0.172 0.027  0.025  
ATOM   3087  O  O   . LEU A 1 418 ? -18.838 1.748   9.739   1    106.86 ? 407 LEU A O   1 -0.173 0.016  0.024  
ATOM   3088  C  CB  . LEU A 1 418 ? -16.864 4.25    9.218   1    101.75 ? 407 LEU A CB  1 -0.155 0.039  0.023  
ATOM   3089  C  CG  . LEU A 1 418 ? -16.197 4.604   7.901   1    100.54 ? 407 LEU A CG  1 -0.148 0.042  0.02   
ATOM   3090  C  CD1 . LEU A 1 418 ? -16.585 6.003   7.531   1    99.02  ? 407 LEU A CD1 1 -0.152 0.055  0.019  
ATOM   3091  C  CD2 . LEU A 1 418 ? -14.681 4.385   8.015   1    106.12 ? 407 LEU A CD2 1 -0.135 0.04   0.02   
ATOM   3092  N  N   . GLN A 1 419 ? -19.083 3.289   11.385  1    100.96 ? 408 GLN A N   1 -0.175 0.03   0.028  
ATOM   3093  C  CA  . GLN A 1 419 ? -19.454 2.301   12.398  1    97.92  ? 408 GLN A CA  1 -0.178 0.021  0.031  
ATOM   3094  C  C   . GLN A 1 419 ? -20.824 1.687   12.124  1    95.91  ? 408 GLN A C   1 -0.191 0.015  0.03   
ATOM   3095  O  O   . GLN A 1 419 ? -21.009 0.479   12.31   1    98.85  ? 408 GLN A O   1 -0.193 0.004  0.031  
ATOM   3096  C  CB  . GLN A 1 419 ? -19.445 2.938   13.79   1    106.91 ? 408 GLN A CB  1 -0.178 0.027  0.034  
ATOM   3097  C  CG  . GLN A 1 419 ? -18.094 2.997   14.477  1    106.39 ? 408 GLN A CG  1 -0.166 0.027  0.036  
ATOM   3098  C  CD  . GLN A 1 419 ? -18.088 4.001   15.607  1    100.9  ? 408 GLN A CD  1 -0.166 0.037  0.039  
ATOM   3099  O  OE1 . GLN A 1 419 ? -19.101 4.647   15.872  1    96.99  ? 408 GLN A OE1 1 -0.175 0.043  0.04   
ATOM   3100  N  NE2 . GLN A 1 419 ? -16.944 4.145   16.273  1    100.74 ? 408 GLN A NE2 1 -0.155 0.038  0.041  
ATOM   3101  N  N   . VAL A 1 420 ? -21.809 2.499   11.723  1    96.88  ? 409 VAL A N   1 -0.2   0.023  0.029  
ATOM   3102  C  CA  . VAL A 1 420 ? -23.12  1.953   11.351  1    99.49  ? 409 VAL A CA  1 -0.212 0.018  0.028  
ATOM   3103  C  C   . VAL A 1 420 ? -23.015 1.037   10.121  1    103.25 ? 409 VAL A C   1 -0.211 0.01   0.025  
ATOM   3104  O  O   . VAL A 1 420 ? -23.723 0.025   10.027  1    97.79  ? 409 VAL A O   1 -0.217 0.0    0.025  
ATOM   3105  C  CB  . VAL A 1 420 ? -24.135 3.09    11.134  1    94.63  ? 409 VAL A CB  1 -0.221 0.028  0.028  
ATOM   3106  C  CG1 . VAL A 1 420 ? -25.251 2.629   10.241  1    106.71 ? 409 VAL A CG1 1 -0.231 0.024  0.026  
ATOM   3107  C  CG2 . VAL A 1 420 ? -24.736 3.524   12.418  1    95.02  ? 409 VAL A CG2 1 -0.227 0.032  0.031  
ATOM   3108  N  N   . ILE A 1 421 ? -22.129 1.362   9.165   1    96.61  ? 410 ILE A N   1 -0.203 0.012  0.023  
ATOM   3109  C  CA  . ILE A 1 421 ? -21.944 0.478   8.013   1    100.97 ? 410 ILE A CA  1 -0.201 0.004  0.02   
ATOM   3110  C  C   . ILE A 1 421 ? -21.269 -0.819  8.439   1    100.98 ? 410 ILE A C   1 -0.195 -0.008 0.021  
ATOM   3111  O  O   . ILE A 1 421 ? -21.679 -1.915  8.034   1    102.32 ? 410 ILE A O   1 -0.199 -0.018 0.02   
ATOM   3112  C  CB  . ILE A 1 421 ? -21.127 1.16    6.899   1    106.73 ? 410 ILE A CB  1 -0.194 0.011  0.017  
ATOM   3113  C  CG1 . ILE A 1 421 ? -21.676 2.52    6.501   1    104.85 ? 410 ILE A CG1 1 -0.199 0.023  0.016  
ATOM   3114  C  CG2 . ILE A 1 421 ? -21.096 0.291   5.635   1    96.55  ? 410 ILE A CG2 1 -0.193 0.003  0.014  
ATOM   3115  C  CD1 . ILE A 1 421 ? -20.914 3.059   5.304   1    101.77 ? 410 ILE A CD1 1 -0.192 0.028  0.013  
ATOM   3116  N  N   . GLU A 1 422 ? -20.182 -0.706  9.212   1    99.04  ? 411 GLU A N   1 -0.185 -0.006 0.023  
ATOM   3117  C  CA  . GLU A 1 422 ? -19.474 -1.889  9.701   1    107.35 ? 411 GLU A CA  1 -0.178 -0.017 0.024  
ATOM   3118  C  C   . GLU A 1 422 ? -20.418 -2.854  10.421  1    105.73 ? 411 GLU A C   1 -0.187 -0.026 0.026  
ATOM   3119  O  O   . GLU A 1 422 ? -20.158 -4.064  10.481  1    108.09 ? 411 GLU A O   1 -0.185 -0.037 0.026  
ATOM   3120  C  CB  . GLU A 1 422 ? -18.333 -1.458  10.636  1    108.71 ? 411 GLU A CB  1 -0.168 -0.013 0.027  
ATOM   3121  C  CG  . GLU A 1 422 ? -17.236 -2.504  10.867  1    112.71 ? 411 GLU A CG  1 -0.158 -0.023 0.027  
ATOM   3122  C  CD  . GLU A 1 422 ? -16.77  -2.559  12.326  1    119.56 ? 411 GLU A CD  1 -0.154 -0.023 0.031  
ATOM   3123  O  OE1 . GLU A 1 422 ? -17.226 -1.719  13.136  1    120.49 ? 411 GLU A OE1 1 -0.158 -0.016 0.033  
ATOM   3124  O  OE2 . GLU A 1 422 ? -15.957 -3.452  12.667  1    115.98 ? 411 GLU A OE2 1 -0.146 -0.032 0.032  
ATOM   3125  N  N   . LYS A 1 423 ? -21.528 -2.345  10.946  1    100.51 ? 412 LYS A N   1 -0.197 -0.021 0.027  
ATOM   3126  C  CA  . LYS A 1 423 ? -22.427 -3.16   11.741  1    104.09 ? 412 LYS A CA  1 -0.206 -0.029 0.029  
ATOM   3127  C  C   . LYS A 1 423 ? -23.575 -3.707  10.9    1    104.58 ? 412 LYS A C   1 -0.216 -0.034 0.027  
ATOM   3128  O  O   . LYS A 1 423 ? -23.866 -4.904  10.954  1    108.43 ? 412 LYS A O   1 -0.219 -0.045 0.027  
ATOM   3129  C  CB  . LYS A 1 423 ? -22.945 -2.333  12.923  1    99.74  ? 412 LYS A CB  1 -0.21  -0.021 0.032  
ATOM   3130  C  CG  . LYS A 1 423 ? -24.1   -2.944  13.654  1    96.34  ? 412 LYS A CG  1 -0.221 -0.027 0.034  
ATOM   3131  C  CD  . LYS A 1 423 ? -24.514 -2.031  14.775  1    107.71 ? 412 LYS A CD  1 -0.225 -0.019 0.037  
ATOM   3132  C  CE  . LYS A 1 423 ? -25.403 -0.92   14.26   1    106.67 ? 412 LYS A CE  1 -0.233 -0.008 0.036  
ATOM   3133  N  NZ  . LYS A 1 423 ? -26.761 -1.447  13.956  1    109.56 ? 412 LYS A NZ  1 -0.245 -0.013 0.035  
ATOM   3134  N  N   . GLN A 1 424 ? -24.208 -2.857  10.092  1    106.74 ? 413 GLN A N   1 -0.222 -0.026 0.025  
ATOM   3135  C  CA  . GLN A 1 424 ? -25.38  -3.27   9.326   1    111.68 ? 413 GLN A CA  1 -0.233 -0.03  0.023  
ATOM   3136  C  C   . GLN A 1 424 ? -25.041 -3.886  7.964   1    112.53 ? 413 GLN A C   1 -0.229 -0.036 0.02   
ATOM   3137  O  O   . GLN A 1 424 ? -25.603 -4.925  7.602   1    115.77 ? 413 GLN A O   1 -0.235 -0.045 0.019  
ATOM   3138  C  CB  . GLN A 1 424 ? -26.325 -2.078  9.137   1    110.25 ? 413 GLN A CB  1 -0.241 -0.019 0.023  
ATOM   3139  C  CG  . GLN A 1 424 ? -27.003 -1.612  10.409  1    109.62 ? 413 GLN A CG  1 -0.247 -0.015 0.026  
ATOM   3140  C  CD  . GLN A 1 424 ? -28.202 -2.481  10.776  1    121.33 ? 413 GLN A CD  1 -0.258 -0.023 0.027  
ATOM   3141  O  OE1 . GLN A 1 424 ? -28.397 -3.562  10.203  1    127.85 ? 413 GLN A OE1 1 -0.26  -0.033 0.025  
ATOM   3142  N  NE2 . GLN A 1 424 ? -29.022 -2.007  11.722  1    115.1  ? 413 GLN A NE2 1 -0.266 -0.018 0.029  
ATOM   3143  N  N   . LEU A 1 425 ? -24.143 -3.271  7.19    1    109.77 ? 414 LEU A N   1 -0.221 -0.03  0.018  
ATOM   3144  C  CA  . LEU A 1 425 ? -23.991 -3.617  5.777   1    118.31 ? 414 LEU A CA  1 -0.22  -0.033 0.014  
ATOM   3145  C  C   . LEU A 1 425 ? -22.749 -4.442  5.482   1    116.63 ? 414 LEU A C   1 -0.208 -0.041 0.014  
ATOM   3146  O  O   . LEU A 1 425 ? -22.412 -4.627  4.311   1    116.43 ? 414 LEU A O   1 -0.205 -0.042 0.011  
ATOM   3147  C  CB  . LEU A 1 425 ? -23.979 -2.356  4.906   1    105.77 ? 414 LEU A CB  1 -0.22  -0.022 0.012  
ATOM   3148  C  CG  . LEU A 1 425 ? -25.206 -1.483  5.161   1    108.83 ? 414 LEU A CG  1 -0.231 -0.014 0.013  
ATOM   3149  C  CD1 . LEU A 1 425 ? -25.087 -0.162  4.447   1    109.52 ? 414 LEU A CD1 1 -0.23  -0.001 0.011  
ATOM   3150  C  CD2 . LEU A 1 425 ? -26.481 -2.219  4.763   1    108.54 ? 414 LEU A CD2 1 -0.243 -0.02  0.012  
ATOM   3151  N  N   . LEU A 1 426 ? -22.063 -4.938  6.502   1    113.77 ? 415 LEU A N   1 -0.202 -0.045 0.016  
ATOM   3152  C  CA  . LEU A 1 426 ? -20.898 -5.758  6.25    1    117.82 ? 415 LEU A CA  1 -0.192 -0.053 0.016  
ATOM   3153  C  C   . LEU A 1 426 ? -21.036 -7.098  6.957   1    129.65 ? 415 LEU A C   1 -0.193 -0.065 0.017  
ATOM   3154  O  O   . LEU A 1 426 ? -21.527 -7.154  8.094   1    131.52 ? 415 LEU A O   1 -0.197 -0.066 0.02   
ATOM   3155  C  CB  . LEU A 1 426 ? -19.615 -5.067  6.727   1    110.07 ? 415 LEU A CB  1 -0.18  -0.046 0.017  
ATOM   3156  C  CG  . LEU A 1 426 ? -18.914 -4.147  5.74    1    110.07 ? 415 LEU A CG  1 -0.173 -0.038 0.014  
ATOM   3157  C  CD1 . LEU A 1 426 ? -19.771 -2.951  5.413   1    111.33 ? 415 LEU A CD1 1 -0.181 -0.027 0.014  
ATOM   3158  C  CD2 . LEU A 1 426 ? -17.58  -3.705  6.294   1    108.28 ? 415 LEU A CD2 1 -0.161 -0.034 0.016  
ATOM   3159  N  N   . PRO A 1 427 ? -20.611 -8.191  6.323   1    135.2  ? 416 PRO A N   1 -0.189 -0.075 0.016  
ATOM   3160  C  CA  . PRO A 1 427 ? -20.585 -9.474  7.033   1    141.35 ? 416 PRO A CA  1 -0.189 -0.087 0.018  
ATOM   3161  C  C   . PRO A 1 427 ? -19.561 -9.419  8.157   1    145.12 ? 416 PRO A C   1 -0.179 -0.086 0.02   
ATOM   3162  O  O   . PRO A 1 427 ? -18.501 -8.802  8.028   1    144.4  ? 416 PRO A O   1 -0.17  -0.081 0.02   
ATOM   3163  C  CB  . PRO A 1 427 ? -20.205 -10.491 5.946   1    141.98 ? 416 PRO A CB  1 -0.185 -0.096 0.015  
ATOM   3164  C  CG  . PRO A 1 427 ? -19.747 -9.696  4.755   1    135.17 ? 416 PRO A CG  1 -0.181 -0.089 0.012  
ATOM   3165  C  CD  . PRO A 1 427 ? -19.876 -8.232  5.047   1    132.62 ? 416 PRO A CD  1 -0.182 -0.075 0.013  
ATOM   3166  N  N   . LYS A 1 428 ? -19.905 -10.041 9.279   1    151.72 ? 417 LYS A N   1 -0.182 -0.092 0.023  
ATOM   3167  C  CA  . LYS A 1 428 ? -19.165 -9.804  10.508  1    153.91 ? 417 LYS A CA  1 -0.176 -0.09  0.026  
ATOM   3168  C  C   . LYS A 1 428 ? -17.928 -10.696 10.586  1    157.99 ? 417 LYS A C   1 -0.164 -0.098 0.026  
ATOM   3169  O  O   . LYS A 1 428 ? -17.901 -11.811 10.055  1    158.51 ? 417 LYS A O   1 -0.164 -0.108 0.025  
ATOM   3170  C  CB  . LYS A 1 428 ? -20.071 -10.033 11.719  1    152.08 ? 417 LYS A CB  1 -0.184 -0.092 0.029  
ATOM   3171  C  CG  . LYS A 1 428 ? -19.478 -9.583  13.056  1    154.68 ? 417 LYS A CG  1 -0.178 -0.088 0.033  
ATOM   3172  C  CD  . LYS A 1 428 ? -19.097 -8.099  13.062  1    150    ? 417 LYS A CD  1 -0.175 -0.074 0.033  
ATOM   3173  C  CE  . LYS A 1 428 ? -20.315 -7.174  13.064  1    141.34 ? 417 LYS A CE  1 -0.186 -0.066 0.033  
ATOM   3174  N  NZ  . LYS A 1 428 ? -19.938 -5.767  13.423  1    127.09 ? 417 LYS A NZ  1 -0.183 -0.053 0.034  
ATOM   3175  N  N   . ASP A 1 429 ? -16.889 -10.18  11.245  1    159.9  ? 418 ASP A N   1 -0.155 -0.093 0.028  
ATOM   3176  C  CA  . ASP A 1 429 ? -15.656 -10.934 11.464  1    162.28 ? 418 ASP A CA  1 -0.143 -0.1   0.029  
ATOM   3177  C  C   . ASP A 1 429 ? -15.42  -11.218 12.96   1    160.77 ? 418 ASP A C   1 -0.141 -0.103 0.032  
ATOM   3178  O  O   . ASP A 1 429 ? -15.167 -10.317 13.767  1    155.07 ? 418 ASP A O   1 -0.139 -0.095 0.034  
ATOM   3179  C  CB  . ASP A 1 429 ? -14.45  -10.195 10.854  1    164.33 ? 418 ASP A CB  1 -0.132 -0.093 0.027  
ATOM   3180  C  CG  . ASP A 1 429 ? -14.143 -8.87   11.551  1    170.9  ? 418 ASP A CG  1 -0.13  -0.081 0.029  
ATOM   3181  O  OD1 . ASP A 1 429 ? -15.034 -7.99   11.601  1    167.91 ? 418 ASP A OD1 1 -0.138 -0.073 0.029  
ATOM   3182  O  OD2 . ASP A 1 429 ? -13.011 -8.721  12.069  1    170.94 ? 418 ASP A OD2 1 -0.119 -0.08  0.03   
ATOM   3183  N  N   . GLU B 1 38  ? -36.033 46.612  28.7    1    137.26 ? 27  GLU B N   1 -0.33  0.427  0.072  
ATOM   3184  C  CA  . GLU B 1 38  ? -35.277 47.548  29.526  1    136.71 ? 27  GLU B CA  1 -0.323 0.436  0.074  
ATOM   3185  C  C   . GLU B 1 38  ? -34.03  48.069  28.788  1    131.74 ? 27  GLU B C   1 -0.312 0.441  0.072  
ATOM   3186  O  O   . GLU B 1 38  ? -33.361 48.978  29.266  1    128.51 ? 27  GLU B O   1 -0.306 0.449  0.073  
ATOM   3187  C  CB  . GLU B 1 38  ? -34.88  46.89   30.866  1    140.9  ? 27  GLU B CB  1 -0.32  0.43   0.077  
ATOM   3188  C  CG  . GLU B 1 38  ? -33.572 46.08   30.848  1    142.16 ? 27  GLU B CG  1 -0.308 0.422  0.077  
ATOM   3189  C  CD  . GLU B 1 38  ? -33.778 44.58   30.633  1    144.74 ? 27  GLU B CD  1 -0.31  0.409  0.076  
ATOM   3190  O  OE1 . GLU B 1 38  ? -34.945 44.123  30.621  1    145.07 ? 27  GLU B OE1 1 -0.32  0.404  0.076  
ATOM   3191  O  OE2 . GLU B 1 38  ? -32.764 43.858  30.485  1    140.22 ? 27  GLU B OE2 1 -0.3   0.402  0.076  
ATOM   3192  N  N   . GLU B 1 39  ? -33.731 47.508  27.611  1    129.36 ? 28  GLU B N   1 -0.309 0.435  0.069  
ATOM   3193  C  CA  . GLU B 1 39  ? -32.523 47.905  26.888  1    131    ? 28  GLU B CA  1 -0.298 0.439  0.067  
ATOM   3194  C  C   . GLU B 1 39  ? -32.599 49.356  26.405  1    128.03 ? 28  GLU B C   1 -0.299 0.452  0.066  
ATOM   3195  O  O   . GLU B 1 39  ? -31.6   50.084  26.457  1    123.89 ? 28  GLU B O   1 -0.29  0.459  0.066  
ATOM   3196  C  CB  . GLU B 1 39  ? -32.281 46.958  25.705  1    138.15 ? 28  GLU B CB  1 -0.296 0.43   0.064  
ATOM   3197  C  CG  . GLU B 1 39  ? -30.813 46.84   25.231  1    136.84 ? 28  GLU B CG  1 -0.282 0.429  0.063  
ATOM   3198  C  CD  . GLU B 1 39  ? -30.309 48.064  24.464  1    134.74 ? 28  GLU B CD  1 -0.278 0.44   0.061  
ATOM   3199  O  OE1 . GLU B 1 39  ? -31.146 48.876  24.009  1    133.81 ? 28  GLU B OE1 1 -0.285 0.448  0.06   
ATOM   3200  O  OE2 . GLU B 1 39  ? -29.071 48.212  24.317  1    130.98 ? 28  GLU B OE2 1 -0.266 0.442  0.061  
ATOM   3201  N  N   . CYS B 1 40  ? -33.758 49.794  25.906  1    122.72 ? 29  CYS B N   1 -0.309 0.456  0.065  
ATOM   3202  C  CA  . CYS B 1 40  ? -33.915 51.162  25.436  1    115.53 ? 29  CYS B CA  1 -0.311 0.469  0.064  
ATOM   3203  C  C   . CYS B 1 40  ? -35.231 51.757  25.93   1    113.32 ? 29  CYS B C   1 -0.323 0.474  0.065  
ATOM   3204  O  O   . CYS B 1 40  ? -36.194 51.035  26.209  1    114.13 ? 29  CYS B O   1 -0.332 0.468  0.065  
ATOM   3205  C  CB  . CYS B 1 40  ? -33.845 51.227  23.907  1    121.44 ? 29  CYS B CB  1 -0.31  0.469  0.06   
ATOM   3206  S  SG  . CYS B 1 40  ? -33.837 52.913  23.236  1    116.48 ? 29  CYS B SG  1 -0.31  0.485  0.058  
ATOM   3207  N  N   . ALA B 1 41  ? -35.262 53.087  26.046  1    105.64 ? 30  ALA B N   1 -0.323 0.486  0.065  
ATOM   3208  C  CA  . ALA B 1 41  ? -36.479 53.784  26.439  1    106.24 ? 30  ALA B CA  1 -0.334 0.493  0.066  
ATOM   3209  C  C   . ALA B 1 41  ? -36.497 55.193  25.855  1    103.7  ? 30  ALA B C   1 -0.334 0.506  0.065  
ATOM   3210  O  O   . ALA B 1 41  ? -35.449 55.812  25.644  1    96     ? 30  ALA B O   1 -0.325 0.511  0.064  
ATOM   3211  C  CB  . ALA B 1 41  ? -36.624 53.855  27.965  1    109.65 ? 30  ALA B CB  1 -0.336 0.494  0.07   
ATOM   3212  N  N   . ILE B 1 42  ? -37.708 55.697  25.608  1    102.44 ? 31  ILE B N   1 -0.346 0.51   0.064  
ATOM   3213  C  CA  . ILE B 1 42  ? -37.94  57.086  25.219  1    101.28 ? 31  ILE B CA  1 -0.348 0.523  0.063  
ATOM   3214  C  C   . ILE B 1 42  ? -39.037 57.653  26.115  1    110.42 ? 31  ILE B C   1 -0.358 0.528  0.065  
ATOM   3215  O  O   . ILE B 1 42  ? -40.167 57.145  26.119  1    109.33 ? 31  ILE B O   1 -0.368 0.524  0.065  
ATOM   3216  C  CB  . ILE B 1 42  ? -38.316 57.219  23.741  1    101.11 ? 31  ILE B CB  1 -0.351 0.524  0.059  
ATOM   3217  C  CG1 . ILE B 1 42  ? -37.053 57.19   22.901  1    108.82 ? 31  ILE B CG1 1 -0.34  0.524  0.057  
ATOM   3218  C  CG2 . ILE B 1 42  ? -39.072 58.514  23.477  1    101.01 ? 31  ILE B CG2 1 -0.358 0.536  0.059  
ATOM   3219  C  CD1 . ILE B 1 42  ? -37.26  56.583  21.555  1    102.19 ? 31  ILE B CD1 1 -0.341 0.519  0.054  
ATOM   3220  N  N   . GLN B 1 43  ? -38.71  58.716  26.853  1    108.47 ? 32  GLN B N   1 -0.355 0.538  0.067  
ATOM   3221  C  CA  . GLN B 1 43  ? -39.518 59.24   27.951  1    106.58 ? 32  GLN B CA  1 -0.362 0.543  0.07   
ATOM   3222  C  C   . GLN B 1 43  ? -40.194 60.544  27.536  1    103.83 ? 32  GLN B C   1 -0.368 0.555  0.069  
ATOM   3223  O  O   . GLN B 1 43  ? -39.515 61.49   27.111  1    101.56 ? 32  GLN B O   1 -0.362 0.564  0.068  
ATOM   3224  C  CB  . GLN B 1 43  ? -38.625 59.457  29.18   1    105.01 ? 32  GLN B CB  1 -0.354 0.545  0.073  
ATOM   3225  C  CG  . GLN B 1 43  ? -39.304 60.049  30.413  1    111.25 ? 32  GLN B CG  1 -0.36  0.55   0.076  
ATOM   3226  C  CD  . GLN B 1 43  ? -38.373 60.136  31.638  1    108.17 ? 32  GLN B CD  1 -0.352 0.551  0.079  
ATOM   3227  O  OE1 . GLN B 1 43  ? -37.444 59.333  31.801  1    103.69 ? 32  GLN B OE1 1 -0.343 0.544  0.079  
ATOM   3228  N  NE2 . GLN B 1 43  ? -38.625 61.117  32.495  1    101.44 ? 32  GLN B NE2 1 -0.354 0.56   0.081  
ATOM   3229  N  N   . ILE B 1 44  ? -41.521 60.595  27.657  1    97.64  ? 33  ILE B N   1 -0.381 0.555  0.069  
ATOM   3230  C  CA  . ILE B 1 44  ? -42.283 61.811  27.375  1    99.32  ? 33  ILE B CA  1 -0.387 0.566  0.068  
ATOM   3231  C  C   . ILE B 1 44  ? -43.125 62.174  28.596  1    101.65 ? 33  ILE B C   1 -0.395 0.57   0.071  
ATOM   3232  O  O   . ILE B 1 44  ? -43.546 61.28   29.344  1    107    ? 33  ILE B O   1 -0.399 0.562  0.073  
ATOM   3233  C  CB  . ILE B 1 44  ? -43.151 61.642  26.114  1    101.87 ? 33  ILE B CB  1 -0.395 0.565  0.065  
ATOM   3234  C  CG1 . ILE B 1 44  ? -44.164 60.507  26.277  1    101.72 ? 33  ILE B CG1 1 -0.405 0.554  0.066  
ATOM   3235  C  CG2 . ILE B 1 44  ? -42.282 61.336  24.921  1    105    ? 33  ILE B CG2 1 -0.387 0.562  0.062  
ATOM   3236  C  CD1 . ILE B 1 44  ? -45.612 61.032  26.474  1    106.52 ? 33  ILE B CD1 1 -0.418 0.559  0.066  
ATOM   3237  N  N   . PRO B 1 45  ? -43.362 63.456  28.863  1    95.55  ? 34  PRO B N   1 -0.397 0.582  0.072  
ATOM   3238  C  CA  . PRO B 1 45  ? -44.202 63.813  30.005  1    100.15 ? 34  PRO B CA  1 -0.405 0.585  0.075  
ATOM   3239  C  C   . PRO B 1 45  ? -45.621 63.367  29.744  1    104.64 ? 34  PRO B C   1 -0.418 0.581  0.074  
ATOM   3240  O  O   . PRO B 1 45  ? -46.119 63.449  28.62   1    107.92 ? 34  PRO B O   1 -0.423 0.581  0.071  
ATOM   3241  C  CB  . PRO B 1 45  ? -44.092 65.341  30.072  1    99.89  ? 34  PRO B CB  1 -0.404 0.599  0.075  
ATOM   3242  C  CG  . PRO B 1 45  ? -43.798 65.728  28.699  1    104.52 ? 34  PRO B CG  1 -0.401 0.602  0.072  
ATOM   3243  C  CD  . PRO B 1 45  ? -42.933 64.647  28.118  1    96.11  ? 34  PRO B CD  1 -0.393 0.592  0.07   
ATOM   3244  N  N   . SER B 1 46  ? -46.253 62.846  30.792  1    112.33 ? 35  SER B N   1 -0.424 0.576  0.077  
ATOM   3245  C  CA  . SER B 1 46  ? -47.652 62.447  30.741  1    115.96 ? 35  SER B CA  1 -0.437 0.572  0.077  
ATOM   3246  C  C   . SER B 1 46  ? -48.561 63.622  30.4    1    113.72 ? 35  SER B C   1 -0.445 0.583  0.076  
ATOM   3247  O  O   . SER B 1 46  ? -48.133 64.78   30.316  1    109.09 ? 35  SER B O   1 -0.441 0.594  0.076  
ATOM   3248  C  CB  . SER B 1 46  ? -48.073 61.813  32.074  1    120.45 ? 35  SER B CB  1 -0.441 0.566  0.08   
ATOM   3249  O  OG  . SER B 1 46  ? -48.012 62.726  33.16   1    117.78 ? 35  SER B OG  1 -0.44  0.575  0.083  
ATOM   3250  N  N   . GLU B 1 47  ? -49.836 63.328  30.223  1    116.99 ? 36  GLU B N   1 -0.457 0.58   0.075  
ATOM   3251  C  CA  . GLU B 1 47  ? -50.745 64.349  29.732  1    118.92 ? 36  GLU B CA  1 -0.465 0.59   0.074  
ATOM   3252  C  C   . GLU B 1 47  ? -51.032 65.402  30.796  1    116.07 ? 36  GLU B C   1 -0.468 0.599  0.077  
ATOM   3253  O  O   . GLU B 1 47  ? -51.031 66.604  30.498  1    110.02 ? 36  GLU B O   1 -0.468 0.61   0.076  
ATOM   3254  C  CB  . GLU B 1 47  ? -52.022 63.673  29.241  1    125.92 ? 36  GLU B CB  1 -0.477 0.584  0.073  
ATOM   3255  C  CG  . GLU B 1 47  ? -51.773 62.649  28.119  1    134.68 ? 36  GLU B CG  1 -0.474 0.574  0.07   
ATOM   3256  C  CD  . GLU B 1 47  ? -51.126 61.322  28.578  1    148.24 ? 36  GLU B CD  1 -0.469 0.562  0.071  
ATOM   3257  O  OE1 . GLU B 1 47  ? -51.321 60.312  27.85   1    163.55 ? 36  GLU B OE1 1 -0.47  0.553  0.07   
ATOM   3258  O  OE2 . GLU B 1 47  ? -50.42  61.287  29.618  1    159.02 ? 36  GLU B OE2 1 -0.462 0.562  0.074  
ATOM   3259  N  N   . ILE B 1 48  ? -51.295 64.967  32.039  1    116.96 ? 37  ILE B N   1 -0.47  0.595  0.08   
ATOM   3260  C  CA  . ILE B 1 48  ? -51.387 65.896  33.168  1    113.78 ? 37  ILE B CA  1 -0.471 0.604  0.083  
ATOM   3261  C  C   . ILE B 1 48  ? -50.114 66.729  33.284  1    112.11 ? 37  ILE B C   1 -0.459 0.612  0.083  
ATOM   3262  O  O   . ILE B 1 48  ? -50.166 67.961  33.355  1    107.72 ? 37  ILE B O   1 -0.46  0.623  0.083  
ATOM   3263  C  CB  . ILE B 1 48  ? -51.679 65.136  34.478  1    116.54 ? 37  ILE B CB  1 -0.474 0.597  0.086  
ATOM   3264  C  CG1 . ILE B 1 48  ? -50.492 64.251  34.935  1    121.99 ? 37  ILE B CG1 1 -0.463 0.589  0.087  
ATOM   3265  C  CG2 . ILE B 1 48  ? -52.921 64.318  34.306  1    119.19 ? 37  ILE B CG2 1 -0.485 0.589  0.086  
ATOM   3266  C  CD1 . ILE B 1 48  ? -49.731 64.77   36.222  1    113.56 ? 37  ILE B CD1 1 -0.456 0.594  0.09   
ATOM   3267  N  N   . ASP B 1 49  ? -48.953 66.072  33.301  1    107.59 ? 38  ASP B N   1 -0.449 0.605  0.083  
ATOM   3268  C  CA  . ASP B 1 49  ? -47.682 66.779  33.378  1    106    ? 38  ASP B CA  1 -0.437 0.612  0.083  
ATOM   3269  C  C   . ASP B 1 49  ? -47.534 67.838  32.277  1    111.01 ? 38  ASP B C   1 -0.436 0.622  0.081  
ATOM   3270  O  O   . ASP B 1 49  ? -47.342 69.024  32.576  1    108.85 ? 38  ASP B O   1 -0.434 0.633  0.081  
ATOM   3271  C  CB  . ASP B 1 49  ? -46.548 65.768  33.33   1    110.09 ? 38  ASP B CB  1 -0.427 0.603  0.083  
ATOM   3272  C  CG  . ASP B 1 49  ? -46.28  65.134  34.672  1    108.2  ? 38  ASP B CG  1 -0.424 0.597  0.087  
ATOM   3273  O  OD1 . ASP B 1 49  ? -46.205 65.871  35.656  1    113.49 ? 38  ASP B OD1 1 -0.423 0.604  0.089  
ATOM   3274  O  OD2 . ASP B 1 49  ? -46.145 63.903  34.768  1    113.81 ? 38  ASP B OD2 1 -0.423 0.586  0.087  
ATOM   3275  N  N   . ASN B 1 50  ? -47.559 67.422  30.992  1    110.57 ? 39  ASN B N   1 -0.436 0.618  0.077  
ATOM   3276  C  CA  . ASN B 1 50  ? -47.473 68.383  29.888  1    104.53 ? 39  ASN B CA  1 -0.435 0.627  0.075  
ATOM   3277  C  C   . ASN B 1 50  ? -48.525 69.48   30.029  1    102.44 ? 39  ASN B C   1 -0.445 0.637  0.075  
ATOM   3278  O  O   . ASN B 1 50  ? -48.214 70.665  29.865  1    102.6  ? 39  ASN B O   1 -0.442 0.648  0.075  
ATOM   3279  C  CB  . ASN B 1 50  ? -47.599 67.651  28.543  1    112.42 ? 39  ASN B CB  1 -0.436 0.62   0.071  
ATOM   3280  C  CG  . ASN B 1 50  ? -47.728 68.605  27.323  1    108.43 ? 39  ASN B CG  1 -0.437 0.629  0.068  
ATOM   3281  O  OD1 . ASN B 1 50  ? -48.593 68.412  26.451  1    102.31 ? 39  ASN B OD1 1 -0.445 0.627  0.066  
ATOM   3282  N  ND2 . ASN B 1 50  ? -46.871 69.62   27.263  1    105.46 ? 39  ASN B ND2 1 -0.43  0.638  0.068  
ATOM   3283  N  N   . GLU B 1 51  ? -49.771 69.106  30.364  1    101.59 ? 40  GLU B N   1 -0.456 0.633  0.076  
ATOM   3284  C  CA  . GLU B 1 51  ? -50.821 70.107  30.568  1    111.4  ? 40  GLU B CA  1 -0.466 0.642  0.076  
ATOM   3285  C  C   . GLU B 1 51  ? -50.377 71.204  31.538  1    115.21 ? 40  GLU B C   1 -0.462 0.653  0.079  
ATOM   3286  O  O   . GLU B 1 51  ? -50.555 72.398  31.259  1    112.61 ? 40  GLU B O   1 -0.463 0.663  0.078  
ATOM   3287  C  CB  . GLU B 1 51  ? -52.12  69.454  31.069  1    114.6  ? 40  GLU B CB  1 -0.478 0.636  0.078  
ATOM   3288  C  CG  . GLU B 1 51  ? -53.085 68.989  29.967  1    115.88 ? 40  GLU B CG  1 -0.486 0.632  0.075  
ATOM   3289  C  CD  . GLU B 1 51  ? -54.561 69.155  30.341  1    125.6  ? 40  GLU B CD  1 -0.5   0.634  0.076  
ATOM   3290  O  OE1 . GLU B 1 51  ? -54.86  70.04   31.176  1    132.77 ? 40  GLU B OE1 1 -0.503 0.642  0.078  
ATOM   3291  O  OE2 . GLU B 1 51  ? -55.417 68.407  29.8    1    123.4  ? 40  GLU B OE2 1 -0.508 0.627  0.074  
ATOM   3292  N  N   . GLN B 1 52  ? -49.757 70.826  32.662  1    111.14 ? 41  GLN B N   1 -0.456 0.649  0.082  
ATOM   3293  C  CA  . GLN B 1 52  ? -49.34  71.811  33.656  1    112.95 ? 41  GLN B CA  1 -0.452 0.658  0.084  
ATOM   3294  C  C   . GLN B 1 52  ? -48.142 72.649  33.209  1    111.85 ? 41  GLN B C   1 -0.441 0.666  0.083  
ATOM   3295  O  O   . GLN B 1 52  ? -47.429 73.211  34.049  1    108.48 ? 41  GLN B O   1 -0.435 0.671  0.085  
ATOM   3296  C  CB  . GLN B 1 52  ? -48.991 71.138  34.998  1    119.42 ? 41  GLN B CB  1 -0.449 0.652  0.087  
ATOM   3297  C  CG  . GLN B 1 52  ? -49.935 70.046  35.52   1    116.12 ? 41  GLN B CG  1 -0.458 0.642  0.089  
ATOM   3298  C  CD  . GLN B 1 52  ? -51.306 70.541  35.983  1    118.8  ? 41  GLN B CD  1 -0.47  0.646  0.09   
ATOM   3299  O  OE1 . GLN B 1 52  ? -51.773 71.623  35.605  1    114.31 ? 41  GLN B OE1 1 -0.474 0.656  0.089  
ATOM   3300  N  NE2 . GLN B 1 52  ? -51.964 69.726  36.808  1    121.63 ? 41  GLN B NE2 1 -0.476 0.639  0.092  
ATOM   3301  N  N   . MET B 1 53  ? -47.906 72.759  31.9    1    115.08 ? 42  MET B N   1 -0.439 0.667  0.08   
ATOM   3302  C  CA  . MET B 1 53  ? -46.706 73.424  31.407  1    112.55 ? 42  MET B CA  1 -0.428 0.673  0.078  
ATOM   3303  C  C   . MET B 1 53  ? -47.021 74.67   30.581  1    115.54 ? 42  MET B C   1 -0.431 0.684  0.076  
ATOM   3304  O  O   . MET B 1 53  ? -46.139 75.184  29.882  1    119.07 ? 42  MET B O   1 -0.423 0.689  0.075  
ATOM   3305  C  CB  . MET B 1 53  ? -45.857 72.438  30.609  1    112.19 ? 42  MET B CB  1 -0.42  0.664  0.076  
ATOM   3306  C  CG  . MET B 1 53  ? -45.463 71.182  31.373  1    109.27 ? 42  MET B CG  1 -0.417 0.652  0.078  
ATOM   3307  S  SD  . MET B 1 53  ? -44.463 70.159  30.262  1    114.8  ? 42  MET B SD  1 -0.407 0.643  0.076  
ATOM   3308  C  CE  . MET B 1 53  ? -43.309 71.391  29.632  1    111.67 ? 42  MET B CE  1 -0.397 0.654  0.074  
ATOM   3309  N  N   . GLN B 1 54  ? -48.245 75.19   30.673  1    113.44 ? 43  GLN B N   1 -0.442 0.689  0.077  
ATOM   3310  C  CA  . GLN B 1 54  ? -48.594 76.395  29.933  1    115.75 ? 43  GLN B CA  1 -0.445 0.7    0.075  
ATOM   3311  C  C   . GLN B 1 54  ? -47.857 77.615  30.493  1    113.81 ? 43  GLN B C   1 -0.439 0.711  0.076  
ATOM   3312  O  O   . GLN B 1 54  ? -47.4   77.632  31.637  1    119.08 ? 43  GLN B O   1 -0.434 0.711  0.079  
ATOM   3313  C  CB  . GLN B 1 54  ? -50.101 76.618  29.977  1    114.43 ? 43  GLN B CB  1 -0.459 0.702  0.075  
ATOM   3314  C  CG  . GLN B 1 54  ? -50.866 75.316  29.908  1    117.63 ? 43  GLN B CG  1 -0.466 0.69   0.075  
ATOM   3315  C  CD  . GLN B 1 54  ? -52.357 75.53   29.771  1    128.36 ? 43  GLN B CD  1 -0.48  0.692  0.074  
ATOM   3316  O  OE1 . GLN B 1 54  ? -52.867 75.75   28.666  1    120.51 ? 43  GLN B OE1 1 -0.484 0.694  0.072  
ATOM   3317  N  NE2 . GLN B 1 54  ? -53.071 75.469  30.9    1    140.54 ? 43  GLN B NE2 1 -0.486 0.692  0.077  
ATOM   3318  N  N   . ARG B 1 55  ? -47.706 78.629  29.64   1    113.28 ? 44  ARG B N   1 -0.437 0.721  0.074  
ATOM   3319  C  CA  . ARG B 1 55  ? -47.11  79.915  29.999  1    116.9  ? 44  ARG B CA  1 -0.432 0.732  0.075  
ATOM   3320  C  C   . ARG B 1 55  ? -45.617 79.821  30.315  1    114.42 ? 44  ARG B C   1 -0.418 0.731  0.076  
ATOM   3321  O  O   . ARG B 1 55  ? -44.935 80.845  30.421  1    112.4  ? 44  ARG B O   1 -0.412 0.741  0.076  
ATOM   3322  C  CB  . ARG B 1 55  ? -47.877 80.542  31.166  1    118.58 ? 44  ARG B CB  1 -0.439 0.738  0.078  
ATOM   3323  C  CG  . ARG B 1 55  ? -49.376 80.51   30.951  1    123.6  ? 44  ARG B CG  1 -0.452 0.738  0.077  
ATOM   3324  C  CD  . ARG B 1 55  ? -50.123 81.417  31.9    1    128.75 ? 44  ARG B CD  1 -0.459 0.746  0.08   
ATOM   3325  N  NE  . ARG B 1 55  ? -49.934 82.835  31.608  1    134.96 ? 44  ARG B NE  1 -0.458 0.759  0.079  
ATOM   3326  C  CZ  . ARG B 1 55  ? -50.603 83.509  30.68   1    144.98 ? 44  ARG B CZ  1 -0.464 0.765  0.077  
ATOM   3327  N  NH1 . ARG B 1 55  ? -51.467 82.907  29.872  1    149.89 ? 44  ARG B NH1 1 -0.472 0.76   0.075  
ATOM   3328  N  NH2 . ARG B 1 55  ? -50.398 84.819  30.554  1    144.2  ? 44  ARG B NH2 1 -0.462 0.777  0.076  
ATOM   3329  N  N   . MET B 1 56  ? -45.089 78.616  30.429  1    111.06 ? 45  MET B N   1 -0.413 0.72   0.076  
ATOM   3330  C  CA  . MET B 1 56  ? -43.651 78.47   30.602  1    111.99 ? 45  MET B CA  1 -0.4   0.719  0.076  
ATOM   3331  C  C   . MET B 1 56  ? -42.929 78.881  29.323  1    111.72 ? 45  MET B C   1 -0.393 0.723  0.073  
ATOM   3332  O  O   . MET B 1 56  ? -43.206 78.329  28.257  1    111.98 ? 45  MET B O   1 -0.396 0.718  0.071  
ATOM   3333  C  CB  . MET B 1 56  ? -43.312 77.041  30.952  1    114.57 ? 45  MET B CB  1 -0.397 0.706  0.077  
ATOM   3334  C  CG  . MET B 1 56  ? -44.175 76.459  32.036  1    115.2  ? 45  MET B CG  1 -0.405 0.701  0.08   
ATOM   3335  S  SD  . MET B 1 56  ? -43.174 75.254  32.899  1    115.43 ? 45  MET B SD  1 -0.396 0.69   0.082  
ATOM   3336  C  CE  . MET B 1 56  ? -41.7   76.25   33.178  1    116.43 ? 45  MET B CE  1 -0.382 0.699  0.083  
ATOM   3337  N  N   . PRO B 1 57  ? -41.964 79.791  29.398  1    112.74 ? 46  PRO B N   1 -0.385 0.731  0.073  
ATOM   3338  C  CA  . PRO B 1 57  ? -41.437 80.423  28.187  1    116.76 ? 46  PRO B CA  1 -0.38  0.737  0.07   
ATOM   3339  C  C   . PRO B 1 57  ? -40.523 79.489  27.4    1    116.36 ? 46  PRO B C   1 -0.371 0.728  0.068  
ATOM   3340  O  O   . PRO B 1 57  ? -39.943 78.538  27.926  1    112.55 ? 46  PRO B O   1 -0.366 0.72   0.07   
ATOM   3341  C  CB  . PRO B 1 57  ? -40.655 81.616  28.739  1    116.52 ? 46  PRO B CB  1 -0.373 0.748  0.072  
ATOM   3342  C  CG  . PRO B 1 57  ? -40.109 81.092  30.04   1    121.55 ? 46  PRO B CG  1 -0.368 0.743  0.075  
ATOM   3343  C  CD  . PRO B 1 57  ? -41.148 80.113  30.581  1    121.83 ? 46  PRO B CD  1 -0.377 0.734  0.076  
ATOM   3344  N  N   . ALA B 1 58  ? -40.41  79.79   26.104  1    114.25 ? 47  ALA B N   1 -0.37  0.731  0.065  
ATOM   3345  C  CA  . ALA B 1 58  ? -39.533 79.051  25.207  1    114.28 ? 47  ALA B CA  1 -0.362 0.724  0.063  
ATOM   3346  C  C   . ALA B 1 58  ? -38.953 80.017  24.183  1    113.68 ? 47  ALA B C   1 -0.357 0.733  0.06   
ATOM   3347  O  O   . ALA B 1 58  ? -39.409 81.156  24.045  1    117.53 ? 47  ALA B O   1 -0.361 0.744  0.06   
ATOM   3348  C  CB  . ALA B 1 58  ? -40.272 77.893  24.523  1    111.12 ? 47  ALA B CB  1 -0.369 0.714  0.061  
ATOM   3349  N  N   . GLY B 1 59  ? -37.925 79.553  23.464  1    108.23 ? 48  GLY B N   1 -0.348 0.729  0.059  
ATOM   3350  C  CA  . GLY B 1 59  ? -37.252 80.421  22.513  1    112.74 ? 48  GLY B CA  1 -0.341 0.737  0.056  
ATOM   3351  C  C   . GLY B 1 59  ? -38.122 80.803  21.331  1    121.12 ? 48  GLY B C   1 -0.349 0.74   0.053  
ATOM   3352  O  O   . GLY B 1 59  ? -37.955 81.884  20.752  1    122.92 ? 48  GLY B O   1 -0.348 0.75   0.052  
ATOM   3353  N  N   . GLY B 1 60  ? -39.053 79.927  20.948  1    122.32 ? 49  GLY B N   1 -0.358 0.732  0.052  
ATOM   3354  C  CA  . GLY B 1 60  ? -39.962 80.206  19.861  1    122.69 ? 49  GLY B CA  1 -0.366 0.735  0.05   
ATOM   3355  C  C   . GLY B 1 60  ? -41.233 80.862  20.353  1    125.05 ? 49  GLY B C   1 -0.378 0.741  0.051  
ATOM   3356  O  O   . GLY B 1 60  ? -41.405 81.143  21.54   1    126.48 ? 49  GLY B O   1 -0.379 0.744  0.054  
ATOM   3357  N  N   . GLU B 1 61  ? -42.146 81.095  19.409  1    128.93 ? 50  GLU B N   1 -0.386 0.743  0.048  
ATOM   3358  C  CA  . GLU B 1 61  ? -43.405 81.768  19.7    1    132.12 ? 50  GLU B CA  1 -0.398 0.749  0.049  
ATOM   3359  C  C   . GLU B 1 61  ? -44.455 80.836  20.326  1    127.89 ? 50  GLU B C   1 -0.407 0.741  0.051  
ATOM   3360  O  O   . GLU B 1 61  ? -45.644 81.181  20.348  1    126.19 ? 50  GLU B O   1 -0.418 0.744  0.051  
ATOM   3361  C  CB  . GLU B 1 61  ? -43.939 82.431  18.426  1    139.61 ? 50  GLU B CB  1 -0.403 0.755  0.046  
ATOM   3362  C  CG  . GLU B 1 61  ? -42.897 83.335  17.745  1    147.54 ? 50  GLU B CG  1 -0.393 0.764  0.044  
ATOM   3363  C  CD  . GLU B 1 61  ? -43.469 84.184  16.61   1    155.7  ? 50  GLU B CD  1 -0.398 0.771  0.041  
ATOM   3364  O  OE1 . GLU B 1 61  ? -44.71  84.303  16.515  1    156.31 ? 50  GLU B OE1 1 -0.41  0.773  0.041  
ATOM   3365  O  OE2 . GLU B 1 61  ? -42.675 84.739  15.815  1    154.3  ? 50  GLU B OE2 1 -0.391 0.777  0.039  
ATOM   3366  N  N   . GLU B 1 62  ? -44.032 79.68   20.84   1    125.47 ? 51  GLU B N   1 -0.404 0.73   0.052  
ATOM   3367  C  CA  . GLU B 1 62  ? -44.866 78.787  21.634  1    119.76 ? 51  GLU B CA  1 -0.411 0.722  0.054  
ATOM   3368  C  C   . GLU B 1 62  ? -44.508 78.878  23.108  1    122.15 ? 51  GLU B C   1 -0.408 0.723  0.058  
ATOM   3369  O  O   . GLU B 1 62  ? -43.419 79.321  23.486  1    123.85 ? 51  GLU B O   1 -0.398 0.727  0.059  
ATOM   3370  C  CB  . GLU B 1 62  ? -44.684 77.326  21.231  1    118.13 ? 51  GLU B CB  1 -0.409 0.709  0.053  
ATOM   3371  C  CG  . GLU B 1 62  ? -44.917 76.936  19.809  1    112.47 ? 51  GLU B CG  1 -0.412 0.705  0.049  
ATOM   3372  C  CD  . GLU B 1 62  ? -44.353 75.554  19.568  1    109.27 ? 51  GLU B CD  1 -0.406 0.692  0.049  
ATOM   3373  O  OE1 . GLU B 1 62  ? -43.128 75.384  19.769  1    108.65 ? 51  GLU B OE1 1 -0.395 0.691  0.049  
ATOM   3374  O  OE2 . GLU B 1 62  ? -45.131 74.633  19.235  1    107.75 ? 51  GLU B OE2 1 -0.414 0.684  0.048  
ATOM   3375  N  N   . ASP B 1 63  ? -45.422 78.392  23.94   1    117.87 ? 52  ASP B N   1 -0.416 0.718  0.06   
ATOM   3376  C  CA  . ASP B 1 63  ? -45.049 78.042  25.3    1    115.3  ? 52  ASP B CA  1 -0.413 0.715  0.063  
ATOM   3377  C  C   . ASP B 1 63  ? -44.505 76.619  25.308  1    110.95 ? 52  ASP B C   1 -0.408 0.702  0.063  
ATOM   3378  O  O   . ASP B 1 63  ? -44.756 75.835  24.396  1    112.83 ? 52  ASP B O   1 -0.41  0.695  0.061  
ATOM   3379  C  CB  . ASP B 1 63  ? -46.237 78.173  26.259  1    118.04 ? 52  ASP B CB  1 -0.424 0.716  0.066  
ATOM   3380  C  CG  . ASP B 1 63  ? -47.442 77.34   25.834  1    120.65 ? 52  ASP B CG  1 -0.435 0.709  0.065  
ATOM   3381  O  OD1 . ASP B 1 63  ? -47.262 76.149  25.484  1    117.26 ? 52  ASP B OD1 1 -0.433 0.698  0.064  
ATOM   3382  O  OD2 . ASP B 1 63  ? -48.577 77.876  25.868  1    121.7  ? 52  ASP B OD2 1 -0.445 0.714  0.065  
ATOM   3383  N  N   . GLN B 1 64  ? -43.768 76.279  26.363  1    117.26 ? 53  GLN B N   1 -0.401 0.699  0.066  
ATOM   3384  C  CA  . GLN B 1 64  ? -43.216 74.932  26.452  1    111.77 ? 53  GLN B CA  1 -0.396 0.687  0.066  
ATOM   3385  C  C   . GLN B 1 64  ? -44.295 73.861  26.406  1    113.23 ? 53  GLN B C   1 -0.406 0.677  0.066  
ATOM   3386  O  O   . GLN B 1 64  ? -43.982 72.708  26.096  1    111.46 ? 53  GLN B O   1 -0.403 0.666  0.065  
ATOM   3387  C  CB  . GLN B 1 64  ? -42.373 74.776  27.718  1    103.51 ? 53  GLN B CB  1 -0.388 0.685  0.069  
ATOM   3388  C  CG  . GLN B 1 64  ? -41.025 75.491  27.641  1    107.11 ? 53  GLN B CG  1 -0.376 0.692  0.069  
ATOM   3389  C  CD  . GLN B 1 64  ? -39.949 74.642  26.989  1    103.2  ? 53  GLN B CD  1 -0.366 0.684  0.067  
ATOM   3390  O  OE1 . GLN B 1 64  ? -40.168 73.457  26.725  1    108    ? 53  GLN B OE1 1 -0.368 0.673  0.067  
ATOM   3391  N  NE2 . GLN B 1 64  ? -38.777 75.239  26.729  1    93.59  ? 53  GLN B NE2 1 -0.355 0.69   0.067  
ATOM   3392  N  N   . TYR B 1 65  ? -45.558 74.211  26.673  1    115.22 ? 54  TYR B N   1 -0.417 0.68   0.067  
ATOM   3393  C  CA  . TYR B 1 65  ? -46.62  73.207  26.655  1    114.96 ? 54  TYR B CA  1 -0.427 0.671  0.067  
ATOM   3394  C  C   . TYR B 1 65  ? -46.862 72.685  25.245  1    107.03 ? 54  TYR B C   1 -0.429 0.666  0.063  
ATOM   3395  O  O   . TYR B 1 65  ? -46.797 71.476  25.01   1    106.36 ? 54  TYR B O   1 -0.429 0.655  0.062  
ATOM   3396  C  CB  . TYR B 1 65  ? -47.913 73.764  27.262  1    115.41 ? 54  TYR B CB  1 -0.439 0.676  0.068  
ATOM   3397  C  CG  . TYR B 1 65  ? -49.2   73.12   26.752  1    112.77 ? 54  TYR B CG  1 -0.451 0.67   0.067  
ATOM   3398  C  CD1 . TYR B 1 65  ? -49.486 71.764  26.98   1    103.33 ? 54  TYR B CD1 1 -0.453 0.658  0.067  
ATOM   3399  C  CD2 . TYR B 1 65  ? -50.145 73.883  26.069  1    113.89 ? 54  TYR B CD2 1 -0.46  0.677  0.065  
ATOM   3400  C  CE1 . TYR B 1 65  ? -50.683 71.19   26.521  1    105.93 ? 54  TYR B CE1 1 -0.464 0.652  0.066  
ATOM   3401  C  CE2 . TYR B 1 65  ? -51.335 73.325  25.6    1    114.77 ? 54  TYR B CE2 1 -0.47  0.672  0.064  
ATOM   3402  C  CZ  . TYR B 1 65  ? -51.607 71.984  25.822  1    113.86 ? 54  TYR B CZ  1 -0.473 0.66   0.064  
ATOM   3403  O  OH  . TYR B 1 65  ? -52.803 71.468  25.335  1    102.83 ? 54  TYR B OH  1 -0.484 0.655  0.063  
ATOM   3404  N  N   . LEU B 1 66  ? -47.16  73.584  24.297  1    108.6  ? 55  LEU B N   1 -0.432 0.674  0.061  
ATOM   3405  C  CA  . LEU B 1 66  ? -47.307 73.183  22.891  1    111.29 ? 55  LEU B CA  1 -0.434 0.671  0.057  
ATOM   3406  C  C   . LEU B 1 66  ? -46.047 72.488  22.379  1    104.23 ? 55  LEU B C   1 -0.422 0.664  0.056  
ATOM   3407  O  O   . LEU B 1 66  ? -46.101 71.357  21.877  1    96.01  ? 55  LEU B O   1 -0.422 0.654  0.055  
ATOM   3408  C  CB  . LEU B 1 66  ? -47.619 74.406  22.023  1    110.97 ? 55  LEU B CB  1 -0.436 0.682  0.055  
ATOM   3409  C  CG  . LEU B 1 66  ? -49.063 74.77   21.663  1    116.1  ? 55  LEU B CG  1 -0.45  0.685  0.054  
ATOM   3410  C  CD1 . LEU B 1 66  ? -49.959 74.939  22.885  1    110.06 ? 55  LEU B CD1 1 -0.458 0.687  0.057  
ATOM   3411  C  CD2 . LEU B 1 66  ? -49.085 76.038  20.812  1    122.07 ? 55  LEU B CD2 1 -0.45  0.697  0.052  
ATOM   3412  N  N   . ARG B 1 67  ? -44.897 73.159  22.523  1    103.15 ? 56  ARG B N   1 -0.411 0.67   0.056  
ATOM   3413  C  CA  . ARG B 1 67  ? -43.62  72.643  22.044  1    100.77 ? 56  ARG B CA  1 -0.4   0.666  0.055  
ATOM   3414  C  C   . ARG B 1 67  ? -43.344 71.222  22.523  1    102.11 ? 56  ARG B C   1 -0.397 0.653  0.056  
ATOM   3415  O  O   . ARG B 1 67  ? -42.746 70.428  21.792  1    111.83 ? 56  ARG B O   1 -0.392 0.645  0.054  
ATOM   3416  C  CB  . ARG B 1 67  ? -42.5   73.573  22.491  1    98.59  ? 56  ARG B CB  1 -0.389 0.674  0.056  
ATOM   3417  C  CG  . ARG B 1 67  ? -41.125 72.994  22.341  1    97.56  ? 56  ARG B CG  1 -0.377 0.669  0.056  
ATOM   3418  C  CD  . ARG B 1 67  ? -40.141 73.769  23.185  1    101.68 ? 56  ARG B CD  1 -0.368 0.676  0.058  
ATOM   3419  N  NE  . ARG B 1 67  ? -38.777 73.526  22.745  1    101.07 ? 56  ARG B NE  1 -0.355 0.674  0.057  
ATOM   3420  C  CZ  . ARG B 1 67  ? -37.934 72.692  23.336  1    100.19 ? 56  ARG B CZ  1 -0.348 0.666  0.058  
ATOM   3421  N  NH1 . ARG B 1 67  ? -38.271 72.03   24.435  1    103.19 ? 56  ARG B NH1 1 -0.351 0.66   0.061  
ATOM   3422  N  NH2 . ARG B 1 67  ? -36.719 72.533  22.821  1    91.25  ? 56  ARG B NH2 1 -0.336 0.665  0.057  
ATOM   3423  N  N   . ILE B 1 68  ? -43.748 70.88   23.737  1    104.95 ? 57  ILE B N   1 -0.401 0.65   0.059  
ATOM   3424  C  CA  . ILE B 1 68  ? -43.536 69.52   24.211  1    101.62 ? 57  ILE B CA  1 -0.399 0.637  0.06   
ATOM   3425  C  C   . ILE B 1 68  ? -44.633 68.608  23.69   1    98.13  ? 57  ILE B C   1 -0.409 0.629  0.059  
ATOM   3426  O  O   . ILE B 1 68  ? -44.363 67.481  23.259  1    95.64  ? 57  ILE B O   1 -0.407 0.618  0.058  
ATOM   3427  C  CB  . ILE B 1 68  ? -43.469 69.504  25.751  1    100.49 ? 57  ILE B CB  1 -0.398 0.637  0.064  
ATOM   3428  C  CG1 . ILE B 1 68  ? -42.075 69.895  26.262  1    96.25  ? 57  ILE B CG1 1 -0.386 0.641  0.066  
ATOM   3429  C  CG2 . ILE B 1 68  ? -43.888 68.154  26.284  1    93.84  ? 57  ILE B CG2 1 -0.402 0.625  0.066  
ATOM   3430  C  CD1 . ILE B 1 68  ? -41.063 68.831  26.042  1    99.45  ? 57  ILE B CD1 1 -0.376 0.631  0.065  
ATOM   3431  N  N   . LYS B 1 69  ? -45.882 69.091  23.74   1    101.81 ? 58  LYS B N   1 -0.42  0.633  0.059  
ATOM   3432  C  CA  . LYS B 1 69  ? -47.043 68.33   23.282  1    102.95 ? 58  LYS B CA  1 -0.431 0.626  0.058  
ATOM   3433  C  C   . LYS B 1 69  ? -46.886 67.894  21.835  1    102.14 ? 58  LYS B C   1 -0.43  0.622  0.055  
ATOM   3434  O  O   . LYS B 1 69  ? -47.251 66.767  21.471  1    93.29  ? 58  LYS B O   1 -0.433 0.612  0.054  
ATOM   3435  C  CB  . LYS B 1 69  ? -48.305 69.178  23.436  1    102.9  ? 58  LYS B CB  1 -0.443 0.634  0.059  
ATOM   3436  C  CG  . LYS B 1 69  ? -49.496 68.735  22.614  1    100.35 ? 58  LYS B CG  1 -0.454 0.63   0.056  
ATOM   3437  C  CD  . LYS B 1 69  ? -50.673 69.665  22.878  1    103.48 ? 58  LYS B CD  1 -0.464 0.638  0.057  
ATOM   3438  C  CE  . LYS B 1 69  ? -51.939 69.136  22.227  1    115.03 ? 58  LYS B CE  1 -0.476 0.634  0.055  
ATOM   3439  N  NZ  . LYS B 1 69  ? -53.144 69.908  22.638  1    119.39 ? 58  LYS B NZ  1 -0.487 0.641  0.057  
ATOM   3440  N  N   . HIS B 1 70  ? -46.331 68.775  21.002  1    102.59 ? 59  HIS B N   1 -0.425 0.63   0.052  
ATOM   3441  C  CA  . HIS B 1 70  ? -46.166 68.458  19.59   1    104.77 ? 59  HIS B CA  1 -0.423 0.627  0.049  
ATOM   3442  C  C   . HIS B 1 70  ? -45.173 67.322  19.391  1    104.51 ? 59  HIS B C   1 -0.414 0.617  0.048  
ATOM   3443  O  O   . HIS B 1 70  ? -45.484 66.33   18.716  1    113.68 ? 59  HIS B O   1 -0.417 0.608  0.047  
ATOM   3444  C  CB  . HIS B 1 70  ? -45.749 69.707  18.818  1    103.82 ? 59  HIS B CB  1 -0.419 0.639  0.047  
ATOM   3445  C  CG  . HIS B 1 70  ? -46.871 70.671  18.61   1    104.13 ? 59  HIS B CG  1 -0.43  0.648  0.046  
ATOM   3446  N  ND1 . HIS B 1 70  ? -46.671 72.018  18.395  1    106.67 ? 59  HIS B ND1 1 -0.428 0.66   0.046  
ATOM   3447  C  CD2 . HIS B 1 70  ? -48.213 70.48   18.599  1    101.44 ? 59  HIS B CD2 1 -0.442 0.646  0.046  
ATOM   3448  C  CE1 . HIS B 1 70  ? -47.843 72.616  18.259  1    111.69 ? 59  HIS B CE1 1 -0.438 0.665  0.046  
ATOM   3449  N  NE2 . HIS B 1 70  ? -48.794 71.705  18.375  1    108.54 ? 59  HIS B NE2 1 -0.447 0.657  0.046  
ATOM   3450  N  N   . MET B 1 71  ? -43.973 67.438  19.962  1    93.96  ? 60  MET B N   1 -0.403 0.618  0.05   
ATOM   3451  C  CA  . MET B 1 71  ? -43.042 66.332  19.802  1    96.2   ? 60  MET B CA  1 -0.394 0.608  0.049  
ATOM   3452  C  C   . MET B 1 71  ? -43.516 65.079  20.528  1    101    ? 60  MET B C   1 -0.399 0.596  0.051  
ATOM   3453  O  O   . MET B 1 71  ? -42.966 63.992  20.295  1    98     ? 60  MET B O   1 -0.394 0.586  0.051  
ATOM   3454  C  CB  . MET B 1 71  ? -41.658 66.746  20.282  1    94.19  ? 60  MET B CB  1 -0.382 0.612  0.051  
ATOM   3455  C  CG  . MET B 1 71  ? -41.253 68.164  19.917  1    97.58  ? 60  MET B CG  1 -0.378 0.625  0.05   
ATOM   3456  S  SD  . MET B 1 71  ? -39.662 68.538  20.707  1    107.19 ? 60  MET B SD  1 -0.363 0.628  0.052  
ATOM   3457  C  CE  . MET B 1 71  ? -39.788 67.522  22.164  1    89.68  ? 60  MET B CE  1 -0.365 0.619  0.055  
ATOM   3458  N  N   . SER B 1 72  ? -44.548 65.197  21.366  1    100.93 ? 61  SER B N   1 -0.408 0.597  0.053  
ATOM   3459  C  CA  . SER B 1 72  ? -45.038 64.042  22.104  1    103.44 ? 61  SER B CA  1 -0.413 0.587  0.055  
ATOM   3460  C  C   . SER B 1 72  ? -45.978 63.203  21.252  1    107.49 ? 61  SER B C   1 -0.421 0.579  0.053  
ATOM   3461  O  O   . SER B 1 72  ? -45.816 61.981  21.164  1    108.45 ? 61  SER B O   1 -0.42  0.568  0.053  
ATOM   3462  C  CB  . SER B 1 72  ? -45.718 64.498  23.389  1    106.41 ? 61  SER B CB  1 -0.419 0.591  0.058  
ATOM   3463  O  OG  . SER B 1 72  ? -44.74  64.956  24.309  1    105.59 ? 61  SER B OG  1 -0.41  0.595  0.061  
ATOM   3464  N  N   . ALA B 1 73  ? -46.95  63.846  20.593  1    111    ? 62  ALA B N   1 -0.43  0.585  0.051  
ATOM   3465  C  CA  . ALA B 1 73  ? -47.812 63.124  19.658  1    105.43 ? 62  ALA B CA  1 -0.438 0.578  0.049  
ATOM   3466  C  C   . ALA B 1 73  ? -47.018 62.553  18.491  1    106.11 ? 62  ALA B C   1 -0.431 0.573  0.046  
ATOM   3467  O  O   . ALA B 1 73  ? -47.348 61.474  17.99   1    108.43 ? 62  ALA B O   1 -0.434 0.563  0.045  
ATOM   3468  C  CB  . ALA B 1 73  ? -48.922 64.034  19.143  1    99.28  ? 62  ALA B CB  1 -0.448 0.587  0.048  
ATOM   3469  N  N   . LEU B 1 74  ? -45.971 63.252  18.051  1    103.44 ? 63  LEU B N   1 -0.421 0.58   0.045  
ATOM   3470  C  CA  . LEU B 1 74  ? -45.102 62.707  17.011  1    100.18 ? 63  LEU B CA  1 -0.413 0.575  0.042  
ATOM   3471  C  C   . LEU B 1 74  ? -44.455 61.395  17.458  1    103.42 ? 63  LEU B C   1 -0.407 0.563  0.044  
ATOM   3472  O  O   . LEU B 1 74  ? -44.473 60.4    16.722  1    101.97 ? 63  LEU B O   1 -0.408 0.554  0.042  
ATOM   3473  C  CB  . LEU B 1 74  ? -44.037 63.741  16.637  1    100.82 ? 63  LEU B CB  1 -0.404 0.584  0.042  
ATOM   3474  C  CG  . LEU B 1 74  ? -43.38  63.684  15.25   1    109.15 ? 63  LEU B CG  1 -0.398 0.584  0.038  
ATOM   3475  C  CD1 . LEU B 1 74  ? -42.848 65.073  14.872  1    109.99 ? 63  LEU B CD1 1 -0.393 0.596  0.037  
ATOM   3476  C  CD2 . LEU B 1 74  ? -42.263 62.628  15.155  1    100.36 ? 63  LEU B CD2 1 -0.387 0.574  0.038  
ATOM   3477  N  N   . ILE B 1 75  ? -43.891 61.377  18.675  1    108.29 ? 64  ILE B N   1 -0.402 0.562  0.047  
ATOM   3478  C  CA  . ILE B 1 75  ? -43.23  60.187  19.219  1    102.33 ? 64  ILE B CA  1 -0.396 0.552  0.048  
ATOM   3479  C  C   . ILE B 1 75  ? -44.236 59.069  19.459  1    101    ? 64  ILE B C   1 -0.405 0.541  0.049  
ATOM   3480  O  O   . ILE B 1 75  ? -43.916 57.881  19.305  1    94.68  ? 64  ILE B O   1 -0.402 0.53   0.048  
ATOM   3481  C  CB  . ILE B 1 75  ? -42.49  60.535  20.524  1    101.51 ? 64  ILE B CB  1 -0.389 0.555  0.051  
ATOM   3482  C  CG1 . ILE B 1 75  ? -41.255 61.392  20.275  1    105.61 ? 64  ILE B CG1 1 -0.378 0.563  0.051  
ATOM   3483  C  CG2 . ILE B 1 75  ? -42.05  59.281  21.247  1    102.23 ? 64  ILE B CG2 1 -0.385 0.543  0.053  
ATOM   3484  C  CD1 . ILE B 1 75  ? -40.334 61.435  21.498  1    99.4   ? 64  ILE B CD1 1 -0.37  0.563  0.054  
ATOM   3485  N  N   . LYS B 1 76  ? -45.448 59.424  19.891  1    103.45 ? 65  LYS B N   1 -0.416 0.545  0.05   
ATOM   3486  C  CA  . LYS B 1 76  ? -46.48  58.417  20.11   1    106.95 ? 65  LYS B CA  1 -0.426 0.535  0.05   
ATOM   3487  C  C   . LYS B 1 76  ? -46.901 57.795  18.789  1    110.58 ? 65  LYS B C   1 -0.43  0.53   0.047  
ATOM   3488  O  O   . LYS B 1 76  ? -46.942 56.565  18.651  1    109.89 ? 65  LYS B O   1 -0.43  0.518  0.047  
ATOM   3489  C  CB  . LYS B 1 76  ? -47.686 59.036  20.827  1    108.06 ? 65  LYS B CB  1 -0.437 0.541  0.052  
ATOM   3490  C  CG  . LYS B 1 76  ? -47.44  59.39   22.289  1    105.9  ? 65  LYS B CG  1 -0.435 0.544  0.056  
ATOM   3491  C  CD  . LYS B 1 76  ? -48.689 59.954  22.974  1    109.69 ? 65  LYS B CD  1 -0.446 0.549  0.057  
ATOM   3492  C  CE  . LYS B 1 76  ? -48.386 61.278  23.703  1    114.49 ? 65  LYS B CE  1 -0.443 0.562  0.059  
ATOM   3493  N  NZ  . LYS B 1 76  ? -49.53  61.792  24.537  1    122.32 ? 65  LYS B NZ  1 -0.454 0.566  0.061  
ATOM   3494  N  N   . LYS B 1 77  ? -47.183 58.647  17.793  1    115.47 ? 66  LYS B N   1 -0.432 0.537  0.044  
ATOM   3495  C  CA  . LYS B 1 77  ? -47.668 58.19   16.493  1    108.1  ? 66  LYS B CA  1 -0.437 0.533  0.041  
ATOM   3496  C  C   . LYS B 1 77  ? -46.641 57.316  15.787  1    109.88 ? 66  LYS B C   1 -0.427 0.525  0.039  
ATOM   3497  O  O   . LYS B 1 77  ? -46.99  56.269  15.23   1    119.94 ? 66  LYS B O   1 -0.431 0.516  0.038  
ATOM   3498  C  CB  . LYS B 1 77  ? -48.041 59.399  15.628  1    108.92 ? 66  LYS B CB  1 -0.44  0.544  0.039  
ATOM   3499  C  CG  . LYS B 1 77  ? -49.391 60.025  15.999  1    116.94 ? 66  LYS B CG  1 -0.453 0.55   0.04   
ATOM   3500  C  CD  . LYS B 1 77  ? -49.622 61.39   15.337  1    118.61 ? 66  LYS B CD  1 -0.455 0.563  0.038  
ATOM   3501  C  CE  . LYS B 1 77  ? -50.896 62.047  15.882  1    119.12 ? 66  LYS B CE  1 -0.466 0.569  0.04   
ATOM   3502  N  NZ  . LYS B 1 77  ? -50.997 63.488  15.501  1    120.41 ? 66  LYS B NZ  1 -0.467 0.582  0.039  
ATOM   3503  N  N   . TYR B 1 78  ? -45.375 57.729  15.788  1    104.31 ? 67  TYR B N   1 -0.416 0.529  0.039  
ATOM   3504  C  CA  . TYR B 1 78  ? -44.312 56.906  15.223  1    105.21 ? 67  TYR B CA  1 -0.406 0.521  0.038  
ATOM   3505  C  C   . TYR B 1 78  ? -44.333 55.499  15.824  1    108.17 ? 67  TYR B C   1 -0.406 0.509  0.04   
ATOM   3506  O  O   . TYR B 1 78  ? -44.574 55.318  17.02   1    116.47 ? 67  TYR B O   1 -0.408 0.507  0.042  
ATOM   3507  C  CB  . TYR B 1 78  ? -42.964 57.585  15.473  1    101.85 ? 67  TYR B CB  1 -0.394 0.528  0.039  
ATOM   3508  C  CG  . TYR B 1 78  ? -41.775 57.03   14.724  1    105.57 ? 67  TYR B CG  1 -0.383 0.523  0.037  
ATOM   3509  C  CD1 . TYR B 1 78  ? -41.092 57.808  13.793  1    102.48 ? 67  TYR B CD1 1 -0.377 0.53   0.034  
ATOM   3510  C  CD2 . TYR B 1 78  ? -41.302 55.739  14.985  1    105.48 ? 67  TYR B CD2 1 -0.378 0.511  0.037  
ATOM   3511  C  CE1 . TYR B 1 78  ? -39.984 57.316  13.114  1    105.19 ? 67  TYR B CE1 1 -0.366 0.525  0.033  
ATOM   3512  C  CE2 . TYR B 1 78  ? -40.195 55.229  14.302  1    111.12 ? 67  TYR B CE2 1 -0.368 0.506  0.036  
ATOM   3513  C  CZ  . TYR B 1 78  ? -39.537 56.02   13.37   1    113.07 ? 67  TYR B CZ  1 -0.362 0.513  0.033  
ATOM   3514  O  OH  . TYR B 1 78  ? -38.434 55.52   12.693  1    111.41 ? 67  TYR B OH  1 -0.352 0.509  0.032  
ATOM   3515  N  N   . GLY B 1 79  ? -44.144 54.505  14.956  1    114.07 ? 68  GLY B N   1 -0.405 0.499  0.037  
ATOM   3516  C  CA  . GLY B 1 79  ? -43.939 53.086  15.236  1    120.03 ? 68  GLY B CA  1 -0.403 0.486  0.038  
ATOM   3517  C  C   . GLY B 1 79  ? -44.127 52.45   16.608  1    119.32 ? 68  GLY B C   1 -0.404 0.481  0.041  
ATOM   3518  O  O   . GLY B 1 79  ? -45.095 52.75   17.312  1    108.82 ? 68  GLY B O   1 -0.413 0.483  0.043  
ATOM   3519  N  N   . ASP B 1 80  ? -43.301 51.456  16.968  1    121.3  ? 69  ASP B N   1 -0.397 0.472  0.042  
ATOM   3520  C  CA  . ASP B 1 80  ? -43.459 50.827  18.293  1    124.08 ? 69  ASP B CA  1 -0.398 0.466  0.046  
ATOM   3521  C  C   . ASP B 1 80  ? -42.14  51.072  19.03   1    128.14 ? 69  ASP B C   1 -0.386 0.468  0.048  
ATOM   3522  O  O   . ASP B 1 80  ? -41.362 50.129  19.198  1    132.54 ? 69  ASP B O   1 -0.379 0.459  0.048  
ATOM   3523  C  CB  . ASP B 1 80  ? -43.875 49.193  18.33   1    132.47 ? 69  ASP B CB  1 -0.402 0.451  0.046  
ATOM   3524  C  CG  . ASP B 1 80  ? -42.993 48.272  17.487  1    141.15 ? 69  ASP B CG  1 -0.394 0.442  0.044  
ATOM   3525  O  OD1 . ASP B 1 80  ? -43.527 47.228  17.081  1    146.21 ? 69  ASP B OD1 1 -0.399 0.433  0.043  
ATOM   3526  O  OD2 . ASP B 1 80  ? -41.79  48.583  17.222  1    143.88 ? 69  ASP B OD2 1 -0.383 0.445  0.043  
ATOM   3527  N  N   . LEU B 1 81  ? -41.917 52.309  19.506  1    123.52 ? 70  LEU B N   1 -0.384 0.479  0.049  
ATOM   3528  C  CA  . LEU B 1 81  ? -40.696 52.612  20.251  1    117.8  ? 70  LEU B CA  1 -0.373 0.482  0.051  
ATOM   3529  C  C   . LEU B 1 81  ? -40.922 52.443  21.744  1    114.13 ? 70  LEU B C   1 -0.375 0.481  0.054  
ATOM   3530  O  O   . LEU B 1 81  ? -42.043 52.619  22.229  1    114.89 ? 70  LEU B O   1 -0.385 0.482  0.056  
ATOM   3531  C  CB  . LEU B 1 81  ? -40.201 54.033  19.973  1    118.05 ? 70  LEU B CB  1 -0.368 0.495  0.05   
ATOM   3532  C  CG  . LEU B 1 81  ? -40.281 54.541  18.529  1    112.53 ? 70  LEU B CG  1 -0.369 0.5    0.046  
ATOM   3533  C  CD1 . LEU B 1 81  ? -41.624 55.204  18.259  1    107.81 ? 70  LEU B CD1 1 -0.381 0.506  0.046  
ATOM   3534  C  CD2 . LEU B 1 81  ? -39.162 55.507  18.211  1    105.67 ? 70  LEU B CD2 1 -0.359 0.509  0.045  
ATOM   3535  N  N   . PRO B 1 82  ? -39.898 52.043  22.47   1    116.74 ? 71  PRO B N   1 -0.366 0.477  0.056  
ATOM   3536  C  CA  . PRO B 1 82  ? -40.076 51.817  23.904  1    107.72 ? 71  PRO B CA  1 -0.367 0.475  0.06   
ATOM   3537  C  C   . PRO B 1 82  ? -40.383 53.12   24.615  1    110.4  ? 71  PRO B C   1 -0.37  0.487  0.061  
ATOM   3538  O  O   . PRO B 1 82  ? -39.471 53.833  25.05   1    109.84 ? 71  PRO B O   1 -0.362 0.493  0.063  
ATOM   3539  C  CB  . PRO B 1 82  ? -38.727 51.223  24.334  1    110.71 ? 71  PRO B CB  1 -0.355 0.469  0.061  
ATOM   3540  C  CG  . PRO B 1 82  ? -37.75  51.772  23.358  1    111.21 ? 71  PRO B CG  1 -0.346 0.474  0.058  
ATOM   3541  C  CD  . PRO B 1 82  ? -38.497 51.858  22.048  1    117.45 ? 71  PRO B CD  1 -0.353 0.475  0.055  
ATOM   3542  N  N   . VAL B 1 83  ? -41.666 53.446  24.742  1    107.74 ? 72  VAL B N   1 -0.382 0.49   0.062  
ATOM   3543  C  CA  . VAL B 1 83  ? -42.09  54.708  25.335  1    107.44 ? 72  VAL B CA  1 -0.386 0.501  0.063  
ATOM   3544  C  C   . VAL B 1 83  ? -42.477 54.47   26.789  1    115    ? 72  VAL B C   1 -0.389 0.499  0.067  
ATOM   3545  O  O   . VAL B 1 83  ? -43.275 53.569  27.094  1    117.8  ? 72  VAL B O   1 -0.397 0.491  0.068  
ATOM   3546  C  CB  . VAL B 1 83  ? -43.239 55.347  24.53   1    114.36 ? 72  VAL B CB  1 -0.396 0.507  0.061  
ATOM   3547  C  CG1 . VAL B 1 83  ? -44.502 54.48   24.563  1    120.32 ? 72  VAL B CG1 1 -0.408 0.499  0.061  
ATOM   3548  C  CG2 . VAL B 1 83  ? -43.525 56.767  25.017  1    107.8  ? 72  VAL B CG2 1 -0.399 0.52   0.062  
ATOM   3549  N  N   . ILE B 1 84  ? -41.869 55.249  27.689  1    118.44 ? 73  ILE B N   1 -0.384 0.506  0.069  
ATOM   3550  C  CA  . ILE B 1 84  ? -42.215 55.303  29.105  1    103.04 ? 73  ILE B CA  1 -0.387 0.507  0.073  
ATOM   3551  C  C   . ILE B 1 84  ? -42.758 56.695  29.385  1    104.32 ? 73  ILE B C   1 -0.392 0.52   0.073  
ATOM   3552  O  O   . ILE B 1 84  ? -42.308 57.677  28.786  1    107.91 ? 73  ILE B O   1 -0.388 0.529  0.072  
ATOM   3553  C  CB  . ILE B 1 84  ? -41.001 54.993  30.007  1    102.57 ? 73  ILE B CB  1 -0.376 0.504  0.075  
ATOM   3554  C  CG1 . ILE B 1 84  ? -39.949 56.1    29.932  1    101.73 ? 73  ILE B CG1 1 -0.366 0.514  0.075  
ATOM   3555  C  CG2 . ILE B 1 84  ? -40.353 53.69   29.604  1    102.22 ? 73  ILE B CG2 1 -0.37  0.492  0.074  
ATOM   3556  C  CD1 . ILE B 1 84  ? -38.8   55.906  30.937  1    110.28 ? 73  ILE B CD1 1 -0.356 0.512  0.077  
ATOM   3557  N  N   . THR B 1 85  ? -43.741 56.785  30.261  1    108.33 ? 74  THR B N   1 -0.401 0.52   0.076  
ATOM   3558  C  CA  . THR B 1 85  ? -44.305 58.079  30.606  1    115.94 ? 74  THR B CA  1 -0.406 0.532  0.076  
ATOM   3559  C  C   . THR B 1 85  ? -44.208 58.341  32.111  1    120.16 ? 74  THR B C   1 -0.405 0.535  0.08   
ATOM   3560  O  O   . THR B 1 85  ? -44.216 57.414  32.931  1    118.85 ? 74  THR B O   1 -0.405 0.526  0.082  
ATOM   3561  C  CB  . THR B 1 85  ? -45.756 58.177  30.14   1    118.16 ? 74  THR B CB  1 -0.419 0.533  0.075  
ATOM   3562  O  OG1 . THR B 1 85  ? -46.184 59.544  30.207  1    122.23 ? 74  THR B OG1 1 -0.423 0.546  0.075  
ATOM   3563  C  CG2 . THR B 1 85  ? -46.668 57.304  31.021  1    119.54 ? 74  THR B CG2 1 -0.428 0.525  0.077  
ATOM   3564  N  N   . THR B 1 86  ? -44.122 59.625  32.477  1    118.26 ? 75  THR B N   1 -0.404 0.546  0.081  
ATOM   3565  C  CA  . THR B 1 86  ? -44.086 60.011  33.888  1    117.9  ? 75  THR B CA  1 -0.404 0.55   0.085  
ATOM   3566  C  C   . THR B 1 86  ? -45.4   59.765  34.616  1    117.74 ? 75  THR B C   1 -0.416 0.548  0.086  
ATOM   3567  O  O   . THR B 1 86  ? -45.514 60.142  35.782  1    118.32 ? 75  THR B O   1 -0.417 0.551  0.089  
ATOM   3568  C  CB  . THR B 1 86  ? -43.716 61.487  34.029  1    112.79 ? 75  THR B CB  1 -0.401 0.563  0.085  
ATOM   3569  O  OG1 . THR B 1 86  ? -44.718 62.286  33.385  1    109.06 ? 75  THR B OG1 1 -0.41  0.571  0.083  
ATOM   3570  C  CG2 . THR B 1 86  ? -42.361 61.753  33.392  1    115.41 ? 75  THR B CG2 1 -0.388 0.566  0.083  
ATOM   3571  N  N   . GLN B 1 87  ? -46.4   59.182  33.962  1    120.55 ? 76  GLN B N   1 -0.425 0.542  0.085  
ATOM   3572  C  CA  . GLN B 1 87  ? -47.59  58.766  34.699  1    123.32 ? 76  GLN B CA  1 -0.436 0.539  0.087  
ATOM   3573  C  C   . GLN B 1 87  ? -47.384 57.408  35.35   1    128.34 ? 76  GLN B C   1 -0.434 0.526  0.088  
ATOM   3574  O  O   . GLN B 1 87  ? -47.916 57.164  36.439  1    128.11 ? 76  GLN B O   1 -0.439 0.524  0.091  
ATOM   3575  C  CB  . GLN B 1 87  ? -48.799 58.731  33.766  1    125.4  ? 76  GLN B CB  1 -0.447 0.538  0.084  
ATOM   3576  C  CG  . GLN B 1 87  ? -50.136 58.448  34.444  1    130.17 ? 76  GLN B CG  1 -0.459 0.536  0.086  
ATOM   3577  C  CD  . GLN B 1 87  ? -51.318 58.706  33.509  1    140.5  ? 76  GLN B CD  1 -0.47  0.538  0.084  
ATOM   3578  O  OE1 . GLN B 1 87  ? -51.884 57.774  32.927  1    138.82 ? 76  GLN B OE1 1 -0.475 0.529  0.082  
ATOM   3579  N  NE2 . GLN B 1 87  ? -51.686 59.981  33.351  1    137.78 ? 76  GLN B NE2 1 -0.474 0.55   0.083  
ATOM   3580  N  N   . GLU B 1 88  ? -46.589 56.531  34.718  1    126.85 ? 77  GLU B N   1 -0.427 0.518  0.087  
ATOM   3581  C  CA  . GLU B 1 88  ? -46.469 55.164  35.217  1    129.9  ? 77  GLU B CA  1 -0.426 0.506  0.088  
ATOM   3582  C  C   . GLU B 1 88  ? -45.75  55.093  36.565  1    126.4  ? 77  GLU B C   1 -0.419 0.505  0.091  
ATOM   3583  O  O   . GLU B 1 88  ? -46.063 54.207  37.367  1    125.43 ? 77  GLU B O   1 -0.422 0.497  0.093  
ATOM   3584  C  CB  . GLU B 1 88  ? -45.758 54.274  34.19   1    124.72 ? 77  GLU B CB  1 -0.419 0.497  0.085  
ATOM   3585  C  CG  . GLU B 1 88  ? -44.279 54.604  33.971  1    126.79 ? 77  GLU B CG  1 -0.406 0.5    0.085  
ATOM   3586  C  CD  . GLU B 1 88  ? -43.323 53.749  34.804  1    138.79 ? 77  GLU B CD  1 -0.397 0.493  0.087  
ATOM   3587  O  OE1 . GLU B 1 88  ? -42.131 53.656  34.406  1    143.38 ? 77  GLU B OE1 1 -0.386 0.492  0.086  
ATOM   3588  O  OE2 . GLU B 1 88  ? -43.749 53.175  35.84   1    138.12 ? 77  GLU B OE2 1 -0.401 0.487  0.089  
ATOM   3589  N  N   . THR B 1 89  ? -44.794 55.991  36.839  1    127.22 ? 78  THR B N   1 -0.41  0.513  0.092  
ATOM   3590  C  CA  . THR B 1 89  ? -43.941 55.876  38.031  1    127.86 ? 78  THR B CA  1 -0.403 0.512  0.095  
ATOM   3591  C  C   . THR B 1 89  ? -44.621 56.533  39.227  1    124.22 ? 78  THR B C   1 -0.409 0.518  0.098  
ATOM   3592  O  O   . THR B 1 89  ? -44.586 57.76   39.373  1    121.22 ? 78  THR B O   1 -0.409 0.529  0.098  
ATOM   3593  C  CB  . THR B 1 89  ? -42.564 56.51   37.819  1    127.02 ? 78  THR B CB  1 -0.39  0.518  0.094  
ATOM   3594  O  OG1 . THR B 1 89  ? -42.254 56.624  36.419  1    118.64 ? 78  THR B OG1 1 -0.387 0.519  0.091  
ATOM   3595  C  CG2 . THR B 1 89  ? -41.49  55.678  38.533  1    119.86 ? 78  THR B CG2 1 -0.38  0.51   0.096  
ATOM   3596  N  N   . ARG B 1 90  ? -45.218 55.728  40.106  1    121.54 ? 79  ARG B N   1 -0.414 0.511  0.1    
ATOM   3597  C  CA  . ARG B 1 90  ? -45.723 56.289  41.35   1    124.62 ? 79  ARG B CA  1 -0.419 0.516  0.103  
ATOM   3598  C  C   . ARG B 1 90  ? -44.538 56.531  42.28   1    120.68 ? 79  ARG B C   1 -0.408 0.518  0.106  
ATOM   3599  O  O   . ARG B 1 90  ? -43.625 55.703  42.369  1    115.53 ? 79  ARG B O   1 -0.4   0.51   0.106  
ATOM   3600  C  CB  . ARG B 1 90  ? -46.765 55.385  42.011  1    127.03 ? 79  ARG B CB  1 -0.429 0.508  0.105  
ATOM   3601  C  CG  . ARG B 1 90  ? -47.514 56.11   43.155  1    132.11 ? 79  ARG B CG  1 -0.435 0.514  0.108  
ATOM   3602  C  CD  . ARG B 1 90  ? -48.339 55.197  44.089  1    129.27 ? 79  ARG B CD  1 -0.443 0.506  0.11   
ATOM   3603  N  NE  . ARG B 1 90  ? -47.531 54.183  44.761  1    127.77 ? 79  ARG B NE  1 -0.436 0.497  0.112  
ATOM   3604  C  CZ  . ARG B 1 90  ? -47.798 52.881  44.759  1    132.42 ? 79  ARG B CZ  1 -0.438 0.485  0.112  
ATOM   3605  N  NH1 . ARG B 1 90  ? -48.893 52.398  44.189  1    132.72 ? 79  ARG B NH1 1 -0.448 0.48   0.11   
ATOM   3606  N  NH2 . ARG B 1 90  ? -46.945 52.041  45.345  1    128.9  ? 79  ARG B NH2 1 -0.43  0.477  0.113  
ATOM   3607  N  N   . LEU B 1 91  ? -44.543 57.68   42.937  1    117.38 ? 80  LEU B N   1 -0.408 0.529  0.107  
ATOM   3608  C  CA  . LEU B 1 91  ? -43.473 58.129  43.814  1    119.96 ? 80  LEU B CA  1 -0.398 0.533  0.109  
ATOM   3609  C  C   . LEU B 1 91  ? -43.672 57.636  45.26   1    116.68 ? 80  LEU B C   1 -0.4   0.528  0.113  
ATOM   3610  O  O   . LEU B 1 91  ? -44.797 57.322  45.67   1    110.43 ? 80  LEU B O   1 -0.411 0.525  0.114  
ATOM   3611  C  CB  . LEU B 1 91  ? -43.398 59.655  43.79   1    117.51 ? 80  LEU B CB  1 -0.398 0.547  0.109  
ATOM   3612  C  CG  . LEU B 1 91  ? -42.646 60.376  42.676  1    108.29 ? 80  LEU B CG  1 -0.391 0.553  0.107  
ATOM   3613  C  CD1 . LEU B 1 91  ? -41.226 59.892  42.674  1    105.73 ? 80  LEU B CD1 1 -0.378 0.549  0.107  
ATOM   3614  C  CD2 . LEU B 1 91  ? -43.285 60.13   41.348  1    116.84 ? 80  LEU B CD2 1 -0.397 0.551  0.103  
ATOM   3615  N  N   . PRO B 1 92  ? -42.584 57.549  46.046  1    117.05 ? 81  PRO B N   1 -0.39  0.527  0.115  
ATOM   3616  C  CA  . PRO B 1 92  ? -42.713 57.217  47.474  1    116.33 ? 81  PRO B CA  1 -0.391 0.524  0.119  
ATOM   3617  C  C   . PRO B 1 92  ? -43.66  58.158  48.202  1    115.07 ? 81  PRO B C   1 -0.4   0.533  0.12   
ATOM   3618  O  O   . PRO B 1 92  ? -43.792 59.336  47.852  1    113.72 ? 81  PRO B O   1 -0.401 0.544  0.119  
ATOM   3619  C  CB  . PRO B 1 92  ? -41.28  57.359  48.005  1    107.19 ? 81  PRO B CB  1 -0.378 0.526  0.12   
ATOM   3620  C  CG  . PRO B 1 92  ? -40.424 57.086  46.848  1    110.73 ? 81  PRO B CG  1 -0.37  0.523  0.117  
ATOM   3621  C  CD  . PRO B 1 92  ? -41.175 57.549  45.613  1    118.21 ? 81  PRO B CD  1 -0.377 0.527  0.114  
ATOM   3622  N  N   . TYR B 1 93  ? -44.323 57.598  49.224  1    114.63 ? 82  TYR B N   1 -0.406 0.528  0.123  
ATOM   3623  C  CA  . TYR B 1 93  ? -45.335 58.283  50.028  1    119.45 ? 82  TYR B CA  1 -0.415 0.534  0.125  
ATOM   3624  C  C   . TYR B 1 93  ? -45.003 59.751  50.296  1    116.64 ? 82  TYR B C   1 -0.412 0.548  0.126  
ATOM   3625  O  O   . TYR B 1 93  ? -45.751 60.648  49.89   1    115.32 ? 82  TYR B O   1 -0.419 0.556  0.125  
ATOM   3626  C  CB  . TYR B 1 93  ? -45.516 57.524  51.352  1    125.51 ? 82  TYR B CB  1 -0.417 0.527  0.128  
ATOM   3627  C  CG  . TYR B 1 93  ? -46.535 58.112  52.317  1    134.81 ? 82  TYR B CG  1 -0.426 0.533  0.131  
ATOM   3628  C  CD1 . TYR B 1 93  ? -46.205 59.163  53.172  1    133.42 ? 82  TYR B CD1 1 -0.423 0.542  0.133  
ATOM   3629  C  CD2 . TYR B 1 93  ? -47.827 57.584  52.396  1    140.33 ? 82  TYR B CD2 1 -0.438 0.528  0.131  
ATOM   3630  C  CE1 . TYR B 1 93  ? -47.143 59.692  54.07   1    146.13 ? 82  TYR B CE1 1 -0.432 0.547  0.135  
ATOM   3631  C  CE2 . TYR B 1 93  ? -48.77  58.1    53.292  1    148.47 ? 82  TYR B CE2 1 -0.447 0.532  0.133  
ATOM   3632  C  CZ  . TYR B 1 93  ? -48.425 59.153  54.125  1    152.61 ? 82  TYR B CZ  1 -0.444 0.542  0.135  
ATOM   3633  O  OH  . TYR B 1 93  ? -49.357 59.665  55.011  1    152.03 ? 82  TYR B OH  1 -0.452 0.547  0.137  
ATOM   3634  N  N   . TYR B 1 94  ? -43.872 60.007  50.97   1    112.47 ? 83  TYR B N   1 -0.402 0.55   0.127  
ATOM   3635  C  CA  . TYR B 1 94  ? -43.563 61.359  51.434  1    112.63 ? 83  TYR B CA  1 -0.399 0.562  0.128  
ATOM   3636  C  C   . TYR B 1 94  ? -43.461 62.358  50.283  1    117.84 ? 83  TYR B C   1 -0.398 0.571  0.126  
ATOM   3637  O  O   . TYR B 1 94  ? -43.916 63.504  50.414  1    120.53 ? 83  TYR B O   1 -0.402 0.582  0.126  
ATOM   3638  C  CB  . TYR B 1 94  ? -42.276 61.367  52.266  1    103.07 ? 83  TYR B CB  1 -0.387 0.562  0.13   
ATOM   3639  C  CG  . TYR B 1 94  ? -41.163 60.483  51.748  1    102.31 ? 83  TYR B CG  1 -0.377 0.554  0.129  
ATOM   3640  C  CD1 . TYR B 1 94  ? -41.157 59.125  52.009  1    99.86  ? 83  TYR B CD1 1 -0.377 0.542  0.13   
ATOM   3641  C  CD2 . TYR B 1 94  ? -40.102 61.012  51.013  1    107.22 ? 83  TYR B CD2 1 -0.368 0.559  0.127  
ATOM   3642  C  CE1 . TYR B 1 94  ? -40.144 58.307  51.537  1    99.05  ? 83  TYR B CE1 1 -0.368 0.534  0.129  
ATOM   3643  C  CE2 . TYR B 1 94  ? -39.075 60.192  50.537  1    102.81 ? 83  TYR B CE2 1 -0.358 0.552  0.126  
ATOM   3644  C  CZ  . TYR B 1 94  ? -39.107 58.84   50.809  1    97.86  ? 83  TYR B CZ  1 -0.358 0.539  0.127  
ATOM   3645  O  OH  . TYR B 1 94  ? -38.108 58.012  50.367  1    96.75  ? 83  TYR B OH  1 -0.349 0.532  0.126  
ATOM   3646  N  N   . TRP B 1 95  ? -42.861 61.963  49.149  1    113.65 ? 84  TRP B N   1 -0.393 0.568  0.123  
ATOM   3647  C  CA  . TRP B 1 95  ? -42.834 62.878  48.009  1    107.35 ? 84  TRP B CA  1 -0.393 0.576  0.12   
ATOM   3648  C  C   . TRP B 1 95  ? -44.238 63.319  47.619  1    107.68 ? 84  TRP B C   1 -0.405 0.58   0.119  
ATOM   3649  O  O   . TRP B 1 95  ? -44.438 64.471  47.215  1    107.78 ? 84  TRP B O   1 -0.407 0.591  0.118  
ATOM   3650  C  CB  . TRP B 1 95  ? -42.14  62.237  46.806  1    110.84 ? 84  TRP B CB  1 -0.386 0.57   0.117  
ATOM   3651  C  CG  . TRP B 1 95  ? -40.638 62.338  46.823  1    104.46 ? 84  TRP B CG  1 -0.372 0.571  0.117  
ATOM   3652  C  CD1 . TRP B 1 95  ? -39.745 61.302  46.95   1    99.83  ? 84  TRP B CD1 1 -0.364 0.562  0.117  
ATOM   3653  C  CD2 . TRP B 1 95  ? -39.852 63.533  46.699  1    96.28  ? 84  TRP B CD2 1 -0.365 0.582  0.117  
ATOM   3654  N  NE1 . TRP B 1 95  ? -38.458 61.786  46.917  1    94.76  ? 84  TRP B NE1 1 -0.352 0.566  0.117  
ATOM   3655  C  CE2 . TRP B 1 95  ? -38.494 63.148  46.765  1    92.82  ? 84  TRP B CE2 1 -0.353 0.579  0.117  
ATOM   3656  C  CE3 . TRP B 1 95  ? -40.164 64.889  46.536  1    92.88  ? 84  TRP B CE3 1 -0.368 0.595  0.116  
ATOM   3657  C  CZ2 . TRP B 1 95  ? -37.453 64.068  46.678  1    87.89  ? 84  TRP B CZ2 1 -0.343 0.587  0.117  
ATOM   3658  C  CZ3 . TRP B 1 95  ? -39.131 65.799  46.445  1    88.56  ? 84  TRP B CZ3 1 -0.359 0.603  0.116  
ATOM   3659  C  CH2 . TRP B 1 95  ? -37.793 65.385  46.52   1    90.75  ? 84  TRP B CH2 1 -0.346 0.599  0.116  
ATOM   3660  N  N   . LEU B 1 96  ? -45.226 62.429  47.753  1    104.41 ? 85  LEU B N   1 -0.414 0.572  0.119  
ATOM   3661  C  CA  . LEU B 1 96  ? -46.593 62.808  47.412  1    109.62 ? 85  LEU B CA  1 -0.427 0.576  0.118  
ATOM   3662  C  C   . LEU B 1 96  ? -47.161 63.827  48.403  1    112.94 ? 85  LEU B C   1 -0.432 0.585  0.121  
ATOM   3663  O  O   . LEU B 1 96  ? -47.895 64.735  47.996  1    110.33 ? 85  LEU B O   1 -0.439 0.593  0.12   
ATOM   3664  C  CB  . LEU B 1 96  ? -47.484 61.563  47.315  1    113.8  ? 85  LEU B CB  1 -0.435 0.564  0.118  
ATOM   3665  C  CG  . LEU B 1 96  ? -47.446 60.742  46.005  1    113.34 ? 85  LEU B CG  1 -0.435 0.557  0.115  
ATOM   3666  C  CD1 . LEU B 1 96  ? -46.08  60.131  45.75   1    112.42 ? 85  LEU B CD1 1 -0.422 0.551  0.114  
ATOM   3667  C  CD2 . LEU B 1 96  ? -48.518 59.646  45.964  1    109.53 ? 85  LEU B CD2 1 -0.445 0.547  0.115  
ATOM   3668  N  N   . ASP B 1 97  ? -46.822 63.713  49.705  1    115.48 ? 86  ASP B N   1 -0.429 0.584  0.124  
ATOM   3669  C  CA  . ASP B 1 97  ? -47.299 64.69   50.696  1    109.66 ? 86  ASP B CA  1 -0.433 0.593  0.127  
ATOM   3670  C  C   . ASP B 1 97  ? -46.591 66.036  50.574  1    110.49 ? 86  ASP B C   1 -0.427 0.605  0.126  
ATOM   3671  O  O   . ASP B 1 97  ? -47.206 67.079  50.824  1    108.58 ? 86  ASP B O   1 -0.433 0.615  0.127  
ATOM   3672  C  CB  . ASP B 1 97  ? -47.119 64.17   52.119  1    116.2  ? 86  ASP B CB  1 -0.432 0.588  0.13   
ATOM   3673  C  CG  . ASP B 1 97  ? -47.616 62.749  52.301  1    126.6  ? 86  ASP B CG  1 -0.436 0.575  0.131  
ATOM   3674  O  OD1 . ASP B 1 97  ? -46.829 61.816  52.035  1    124.98 ? 86  ASP B OD1 1 -0.429 0.566  0.13   
ATOM   3675  O  OD2 . ASP B 1 97  ? -48.779 62.561  52.726  1    129.6  ? 86  ASP B OD2 1 -0.447 0.573  0.132  
ATOM   3676  N  N   . LEU B 1 98  ? -45.298 66.04   50.226  1    109.29 ? 87  LEU B N   1 -0.415 0.605  0.125  
ATOM   3677  C  CA  . LEU B 1 98  ? -44.677 67.283  49.778  1    102.71 ? 87  LEU B CA  1 -0.409 0.617  0.124  
ATOM   3678  C  C   . LEU B 1 98  ? -45.476 67.881  48.629  1    111.18 ? 87  LEU B C   1 -0.417 0.622  0.121  
ATOM   3679  O  O   . LEU B 1 98  ? -45.966 69.01   48.735  1    106.96 ? 87  LEU B O   1 -0.421 0.632  0.122  
ATOM   3680  C  CB  . LEU B 1 98  ? -43.218 67.043  49.384  1    98.98  ? 87  LEU B CB  1 -0.396 0.614  0.123  
ATOM   3681  C  CG  . LEU B 1 98  ? -42.442 68.195  48.729  1    99.41  ? 87  LEU B CG  1 -0.389 0.625  0.122  
ATOM   3682  C  CD1 . LEU B 1 98  ? -42.832 69.569  49.256  1    97.08  ? 87  LEU B CD1 1 -0.393 0.638  0.123  
ATOM   3683  C  CD2 . LEU B 1 98  ? -40.92  67.976  48.861  1    97.68  ? 87  LEU B CD2 1 -0.375 0.623  0.122  
ATOM   3684  N  N   . PHE B 1 99  ? -45.644 67.118  47.533  1    111.83 ? 88  PHE B N   1 -0.418 0.615  0.119  
ATOM   3685  C  CA  . PHE B 1 99  ? -46.558 67.516  46.463  1    112.06 ? 88  PHE B CA  1 -0.427 0.619  0.116  
ATOM   3686  C  C   . PHE B 1 99  ? -47.923 67.911  47.024  1    114.09 ? 88  PHE B C   1 -0.439 0.622  0.117  
ATOM   3687  O  O   . PHE B 1 99  ? -48.458 68.985  46.711  1    110.07 ? 88  PHE B O   1 -0.444 0.632  0.117  
ATOM   3688  C  CB  . PHE B 1 99  ? -46.731 66.38   45.443  1    114.11 ? 88  PHE B CB  1 -0.428 0.608  0.113  
ATOM   3689  C  CG  . PHE B 1 99  ? -45.451 65.925  44.779  1    115.08 ? 88  PHE B CG  1 -0.417 0.604  0.112  
ATOM   3690  C  CD1 . PHE B 1 99  ? -44.414 66.813  44.545  1    110.22 ? 88  PHE B CD1 1 -0.407 0.612  0.111  
ATOM   3691  C  CD2 . PHE B 1 99  ? -45.3   64.6    44.373  1    113.58 ? 88  PHE B CD2 1 -0.415 0.592  0.111  
ATOM   3692  C  CE1 . PHE B 1 99  ? -43.25  66.386  43.94   1    105.51 ? 88  PHE B CE1 1 -0.396 0.608  0.11   
ATOM   3693  C  CE2 . PHE B 1 99  ? -44.129 64.166  43.776  1    108.93 ? 88  PHE B CE2 1 -0.404 0.588  0.109  
ATOM   3694  C  CZ  . PHE B 1 99  ? -43.109 65.064  43.558  1    104.7  ? 88  PHE B CZ  1 -0.395 0.596  0.109  
ATOM   3695  N  N   . ALA B 1 100 ? -48.505 67.039  47.855  1    113.45 ? 89  ALA B N   1 -0.445 0.614  0.119  
ATOM   3696  C  CA  . ALA B 1 100 ? -49.802 67.344  48.453  1    115.95 ? 89  ALA B CA  1 -0.456 0.617  0.121  
ATOM   3697  C  C   . ALA B 1 100 ? -49.772 68.696  49.15   1    119.95 ? 89  ALA B C   1 -0.456 0.63   0.123  
ATOM   3698  O  O   . ALA B 1 100 ? -50.632 69.542  48.9    1    119.5  ? 89  ALA B O   1 -0.464 0.637  0.122  
ATOM   3699  C  CB  . ALA B 1 100 ? -50.227 66.246  49.429  1    111.69 ? 89  ALA B CB  1 -0.46  0.607  0.123  
ATOM   3700  N  N   . ALA B 1 101 ? -48.753 68.933  49.989  1    116.45 ? 90  ALA B N   1 -0.447 0.632  0.125  
ATOM   3701  C  CA  . ALA B 1 101 ? -48.644 70.202  50.71   1    112.92 ? 90  ALA B CA  1 -0.446 0.643  0.127  
ATOM   3702  C  C   . ALA B 1 101 ? -48.56  71.395  49.761  1    119.48 ? 90  ALA B C   1 -0.445 0.654  0.124  
ATOM   3703  O  O   . ALA B 1 101 ? -49.194 72.434  49.996  1    116.94 ? 90  ALA B O   1 -0.451 0.664  0.125  
ATOM   3704  C  CB  . ALA B 1 101 ? -47.429 70.175  51.629  1    108.8  ? 90  ALA B CB  1 -0.435 0.643  0.129  
ATOM   3705  N  N   . ILE B 1 102 ? -47.772 71.28   48.686  1    121.06 ? 91  ILE B N   1 -0.438 0.653  0.122  
ATOM   3706  C  CA  . ILE B 1 102 ? -47.695 72.38   47.731  1    117.15 ? 91  ILE B CA  1 -0.437 0.663  0.119  
ATOM   3707  C  C   . ILE B 1 102 ? -49.046 72.595  47.06   1    118.23 ? 91  ILE B C   1 -0.449 0.665  0.117  
ATOM   3708  O  O   . ILE B 1 102 ? -49.345 73.705  46.606  1    119.59 ? 91  ILE B O   1 -0.452 0.675  0.116  
ATOM   3709  C  CB  . ILE B 1 102 ? -46.576 72.136  46.692  1    110.14 ? 91  ILE B CB  1 -0.427 0.661  0.117  
ATOM   3710  C  CG1 . ILE B 1 102 ? -45.326 71.56   47.338  1    107.14 ? 91  ILE B CG1 1 -0.415 0.656  0.118  
ATOM   3711  C  CG2 . ILE B 1 102 ? -46.175 73.429  46.035  1    110.41 ? 91  ILE B CG2 1 -0.423 0.673  0.115  
ATOM   3712  C  CD1 . ILE B 1 102 ? -44.396 70.972  46.337  1    106.71 ? 91  ILE B CD1 1 -0.407 0.65   0.116  
ATOM   3713  N  N   . ASP B 1 103 ? -49.898 71.568  47.04   1    116.25 ? 92  ASP B N   1 -0.457 0.656  0.117  
ATOM   3714  C  CA  . ASP B 1 103 ? -51.162 71.679  46.319  1    122.14 ? 92  ASP B CA  1 -0.469 0.657  0.116  
ATOM   3715  C  C   . ASP B 1 103 ? -52.146 72.636  46.994  1    123.54 ? 92  ASP B C   1 -0.478 0.666  0.117  
ATOM   3716  O  O   . ASP B 1 103 ? -52.882 73.34   46.292  1    122.86 ? 92  ASP B O   1 -0.485 0.672  0.116  
ATOM   3717  C  CB  . ASP B 1 103 ? -51.797 70.298  46.129  1    124.94 ? 92  ASP B CB  1 -0.475 0.644  0.115  
ATOM   3718  C  CG  . ASP B 1 103 ? -51.256 69.568  44.905  1    130.51 ? 92  ASP B CG  1 -0.47  0.638  0.112  
ATOM   3719  O  OD1 . ASP B 1 103 ? -50.201 69.987  44.373  1    131.95 ? 92  ASP B OD1 1 -0.46  0.641  0.111  
ATOM   3720  O  OD2 . ASP B 1 103 ? -51.895 68.582  44.466  1    135.33 ? 92  ASP B OD2 1 -0.476 0.628  0.111  
ATOM   3721  N  N   . GLU B 1 104 ? -52.191 72.705  48.328  1    125.18 ? 93  GLU B N   1 -0.478 0.666  0.121  
ATOM   3722  C  CA  . GLU B 1 104 ? -53.149 73.616  48.961  1    130.09 ? 93  GLU B CA  1 -0.487 0.675  0.122  
ATOM   3723  C  C   . GLU B 1 104 ? -52.514 74.811  49.677  1    124.46 ? 93  GLU B C   1 -0.481 0.686  0.124  
ATOM   3724  O  O   . GLU B 1 104 ? -53.221 75.528  50.391  1    122.56 ? 93  GLU B O   1 -0.488 0.692  0.126  
ATOM   3725  C  CB  . GLU B 1 104 ? -54.087 72.861  49.918  1    131.13 ? 93  GLU B CB  1 -0.496 0.668  0.125  
ATOM   3726  C  CG  . GLU B 1 104 ? -53.489 72.401  51.225  1    128    ? 93  GLU B CG  1 -0.49  0.663  0.128  
ATOM   3727  C  CD  . GLU B 1 104 ? -52.556 71.238  51.028  1    132.99 ? 93  GLU B CD  1 -0.482 0.653  0.127  
ATOM   3728  O  OE1 . GLU B 1 104 ? -51.728 71.326  50.098  1    125.51 ? 93  GLU B OE1 1 -0.474 0.654  0.125  
ATOM   3729  O  OE2 . GLU B 1 104 ? -52.656 70.243  51.79   1    135.44 ? 93  GLU B OE2 1 -0.483 0.644  0.129  
ATOM   3730  N  N   . GLY B 1 105 ? -51.221 75.073  49.493  1    121.1  ? 94  GLY B N   1 -0.469 0.688  0.124  
ATOM   3731  C  CA  . GLY B 1 105 ? -50.708 76.412  49.706  1    117.83 ? 94  GLY B CA  1 -0.465 0.7    0.124  
ATOM   3732  C  C   . GLY B 1 105 ? -49.983 76.664  51.005  1    120.38 ? 94  GLY B C   1 -0.458 0.703  0.127  
ATOM   3733  O  O   . GLY B 1 105 ? -49.418 77.753  51.174  1    121.65 ? 94  GLY B O   1 -0.453 0.713  0.128  
ATOM   3734  N  N   . ASP B 1 106 ? -49.986 75.71   51.934  1    122.28 ? 95  ASP B N   1 -0.458 0.694  0.13   
ATOM   3735  C  CA  . ASP B 1 106 ? -49.229 75.867  53.171  1    120.38 ? 95  ASP B CA  1 -0.451 0.695  0.133  
ATOM   3736  C  C   . ASP B 1 106 ? -47.731 75.8    52.887  1    112.32 ? 95  ASP B C   1 -0.437 0.695  0.132  
ATOM   3737  O  O   . ASP B 1 106 ? -47.142 74.713  52.847  1    106.89 ? 95  ASP B O   1 -0.432 0.685  0.132  
ATOM   3738  C  CB  . ASP B 1 106 ? -49.638 74.801  54.195  1    119.31 ? 95  ASP B CB  1 -0.455 0.685  0.135  
ATOM   3739  C  CG  . ASP B 1 106 ? -50.972 75.101  54.862  1    130.26 ? 95  ASP B CG  1 -0.467 0.688  0.137  
ATOM   3740  O  OD1 . ASP B 1 106 ? -51.824 75.785  54.234  1    124.96 ? 95  ASP B OD1 1 -0.475 0.695  0.135  
ATOM   3741  O  OD2 . ASP B 1 106 ? -51.158 74.655  56.024  1    132.82 ? 95  ASP B OD2 1 -0.469 0.684  0.14   
ATOM   3742  N  N   . THR B 1 107 ? -47.11  76.962  52.681  1    107.61 ? 96  THR B N   1 -0.432 0.705  0.132  
ATOM   3743  C  CA  . THR B 1 107 ? -45.679 76.995  52.379  1    107.58 ? 96  THR B CA  1 -0.419 0.706  0.131  
ATOM   3744  C  C   . THR B 1 107 ? -44.827 76.402  53.496  1    111.5  ? 96  THR B C   1 -0.411 0.7    0.134  
ATOM   3745  O  O   . THR B 1 107 ? -43.915 75.61   53.194  1    104.85 ? 96  THR B O   1 -0.402 0.693  0.133  
ATOM   3746  C  CB  . THR B 1 107 ? -45.254 78.426  52.029  1    112.47 ? 96  THR B CB  1 -0.415 0.719  0.13   
ATOM   3747  O  OG1 . THR B 1 107 ? -46.2   79.007  51.124  1    113.09 ? 96  THR B OG1 1 -0.423 0.724  0.128  
ATOM   3748  C  CG2 . THR B 1 107 ? -43.877 78.434  51.347  1    109.36 ? 96  THR B CG2 1 -0.402 0.719  0.128  
ATOM   3749  N  N   . PRO B 1 108 ? -45.064 76.704  54.81   1    116.89 ? 97  PRO B N   1 -0.413 0.703  0.137  
ATOM   3750  C  CA  . PRO B 1 108 ? -44.205 76.114  55.855  1    105.73 ? 97  PRO B CA  1 -0.405 0.698  0.139  
ATOM   3751  C  C   . PRO B 1 108 ? -44.53  74.65   56.1    1    106.38 ? 97  PRO B C   1 -0.408 0.684  0.14   
ATOM   3752  O  O   . PRO B 1 108 ? -43.655 73.887  56.519  1    107.97 ? 97  PRO B O   1 -0.4   0.677  0.141  
ATOM   3753  C  CB  . PRO B 1 108 ? -44.499 76.98   57.083  1    106.97 ? 97  PRO B CB  1 -0.408 0.705  0.143  
ATOM   3754  C  CG  . PRO B 1 108 ? -45.316 78.142  56.583  1    107.26 ? 97  PRO B CG  1 -0.415 0.716  0.141  
ATOM   3755  C  CD  . PRO B 1 108 ? -46.061 77.606  55.417  1    110.79 ? 97  PRO B CD  1 -0.422 0.711  0.138  
ATOM   3756  N  N   . LYS B 1 109 ? -45.791 74.259  55.87   1    102.35 ? 98  LYS B N   1 -0.42  0.681  0.139  
ATOM   3757  C  CA  . LYS B 1 109 ? -46.105 72.831  55.806  1    108.65 ? 98  LYS B CA  1 -0.423 0.667  0.139  
ATOM   3758  C  C   . LYS B 1 109 ? -45.263 72.146  54.74   1    105.44 ? 98  LYS B C   1 -0.415 0.661  0.137  
ATOM   3759  O  O   . LYS B 1 109 ? -44.835 70.999  54.908  1    98.77  ? 98  LYS B O   1 -0.411 0.651  0.137  
ATOM   3760  C  CB  . LYS B 1 109 ? -47.598 72.63   55.525  1    111.23 ? 98  LYS B CB  1 -0.436 0.666  0.139  
ATOM   3761  C  CG  . LYS B 1 109 ? -48.117 71.187  55.54   1    109.11 ? 98  LYS B CG  1 -0.441 0.652  0.139  
ATOM   3762  C  CD  . LYS B 1 109 ? -49.645 71.187  55.345  1    116.05 ? 98  LYS B CD  1 -0.455 0.652  0.138  
ATOM   3763  C  CE  . LYS B 1 109 ? -50.279 69.829  55.653  1    122.72 ? 98  LYS B CE  1 -0.461 0.64   0.139  
ATOM   3764  N  NZ  . LYS B 1 109 ? -51.649 69.962  56.263  1    130.81 ? 98  LYS B NZ  1 -0.473 0.641  0.14   
ATOM   3765  N  N   . ALA B 1 110 ? -45.005 72.841  53.634  1    112.56 ? 99  ALA B N   1 -0.412 0.668  0.134  
ATOM   3766  C  CA  . ALA B 1 110 ? -44.173 72.253  52.595  1    114.19 ? 99  ALA B CA  1 -0.405 0.662  0.131  
ATOM   3767  C  C   . ALA B 1 110 ? -42.702 72.39   52.954  1    110.57 ? 99  ALA B C   1 -0.391 0.663  0.132  
ATOM   3768  O  O   . ALA B 1 110 ? -41.96  71.398  52.943  1    112.03 ? 99  ALA B O   1 -0.385 0.654  0.132  
ATOM   3769  C  CB  . ALA B 1 110 ? -44.478 72.898  51.24   1    104.3  ? 99  ALA B CB  1 -0.408 0.668  0.128  
ATOM   3770  N  N   . HIS B 1 111 ? -42.278 73.613  53.289  1    100.61 ? 100 HIS B N   1 -0.387 0.675  0.133  
ATOM   3771  C  CA  . HIS B 1 111 ? -40.884 73.848  53.635  1    103.2  ? 100 HIS B CA  1 -0.375 0.677  0.134  
ATOM   3772  C  C   . HIS B 1 111 ? -40.382 72.796  54.602  1    108.83 ? 100 HIS B C   1 -0.37  0.667  0.136  
ATOM   3773  O  O   . HIS B 1 111 ? -39.351 72.152  54.361  1    102.44 ? 100 HIS B O   1 -0.361 0.661  0.136  
ATOM   3774  C  CB  . HIS B 1 111 ? -40.74  75.233  54.246  1    111.94 ? 100 HIS B CB  1 -0.373 0.689  0.135  
ATOM   3775  C  CG  . HIS B 1 111 ? -40.292 76.272  53.282  1    111.07 ? 100 HIS B CG  1 -0.369 0.699  0.133  
ATOM   3776  N  ND1 . HIS B 1 111 ? -39.318 76.038  52.345  1    117.15 ? 100 HIS B ND1 1 -0.36  0.697  0.131  
ATOM   3777  C  CD2 . HIS B 1 111 ? -40.679 77.557  53.116  1    112.67 ? 100 HIS B CD2 1 -0.373 0.711  0.133  
ATOM   3778  C  CE1 . HIS B 1 111 ? -39.131 77.135  51.633  1    120.64 ? 100 HIS B CE1 1 -0.359 0.707  0.129  
ATOM   3779  N  NE2 . HIS B 1 111 ? -39.94  78.073  52.085  1    119.1  ? 100 HIS B NE2 1 -0.366 0.715  0.13   
ATOM   3780  N  N   . ALA B 1 112 ? -41.132 72.59   55.693  1    114.26 ? 101 ALA B N   1 -0.377 0.665  0.139  
ATOM   3781  C  CA  . ALA B 1 112 ? -40.792 71.594  56.708  1    114.23 ? 101 ALA B CA  1 -0.374 0.656  0.142  
ATOM   3782  C  C   . ALA B 1 112 ? -40.774 70.183  56.128  1    113.98 ? 101 ALA B C   1 -0.374 0.643  0.14   
ATOM   3783  O  O   . ALA B 1 112 ? -39.889 69.375  56.45   1    108.14 ? 101 ALA B O   1 -0.366 0.636  0.141  
ATOM   3784  C  CB  . ALA B 1 112 ? -41.794 71.667  57.865  1    106.16 ? 101 ALA B CB  1 -0.383 0.657  0.144  
ATOM   3785  N  N   . LEU B 1 113 ? -41.775 69.859  55.298  1    108.38 ? 102 LEU B N   1 -0.383 0.64   0.138  
ATOM   3786  C  CA  . LEU B 1 113 ? -41.861 68.52   54.724  1    106.87 ? 102 LEU B CA  1 -0.384 0.628  0.137  
ATOM   3787  C  C   . LEU B 1 113 ? -40.644 68.211  53.863  1    109.11 ? 102 LEU B C   1 -0.372 0.625  0.134  
ATOM   3788  O  O   . LEU B 1 113 ? -39.997 67.167  54.032  1    106.29 ? 102 LEU B O   1 -0.367 0.616  0.135  
ATOM   3789  C  CB  . LEU B 1 113 ? -43.149 68.383  53.914  1    102.36 ? 102 LEU B CB  1 -0.395 0.627  0.135  
ATOM   3790  C  CG  . LEU B 1 113 ? -44.372 68.05   54.769  1    109.11 ? 102 LEU B CG  1 -0.407 0.624  0.137  
ATOM   3791  C  CD1 . LEU B 1 113 ? -45.446 67.321  53.966  1    103.58 ? 102 LEU B CD1 1 -0.416 0.617  0.135  
ATOM   3792  C  CD2 . LEU B 1 113 ? -43.977 67.256  56.028  1    108.94 ? 102 LEU B CD2 1 -0.403 0.616  0.14   
ATOM   3793  N  N   . PHE B 1 114 ? -40.321 69.115  52.926  1    101.64 ? 103 PHE B N   1 -0.37  0.633  0.132  
ATOM   3794  C  CA  . PHE B 1 114 ? -39.112 68.948  52.13   1    105.3  ? 103 PHE B CA  1 -0.358 0.632  0.13   
ATOM   3795  C  C   . PHE B 1 114 ? -37.899 68.721  53.029  1    105.18 ? 103 PHE B C   1 -0.347 0.63   0.132  
ATOM   3796  O  O   . PHE B 1 114 ? -37.156 67.745  52.853  1    104.1  ? 103 PHE B O   1 -0.341 0.621  0.132  
ATOM   3797  C  CB  . PHE B 1 114 ? -38.879 70.156  51.202  1    104.67 ? 103 PHE B CB  1 -0.356 0.643  0.128  
ATOM   3798  C  CG  . PHE B 1 114 ? -37.601 70.057  50.437  1    93.74  ? 103 PHE B CG  1 -0.345 0.642  0.126  
ATOM   3799  C  CD1 . PHE B 1 114 ? -37.546 69.306  49.263  1    109.32 ? 103 PHE B CD1 1 -0.344 0.635  0.123  
ATOM   3800  C  CD2 . PHE B 1 114 ? -36.444 70.634  50.924  1    87.93  ? 103 PHE B CD2 1 -0.334 0.647  0.127  
ATOM   3801  C  CE1 . PHE B 1 114 ? -36.349 69.164  48.557  1    109.55 ? 103 PHE B CE1 1 -0.333 0.634  0.121  
ATOM   3802  C  CE2 . PHE B 1 114 ? -35.253 70.499  50.267  1    102.89 ? 103 PHE B CE2 1 -0.323 0.646  0.126  
ATOM   3803  C  CZ  . PHE B 1 114 ? -35.194 69.768  49.06   1    119.95 ? 103 PHE B CZ  1 -0.323 0.639  0.122  
ATOM   3804  N  N   . HIS B 1 115 ? -37.692 69.613  54.011  1    108.4  ? 104 HIS B N   1 -0.345 0.638  0.135  
ATOM   3805  C  CA  . HIS B 1 115 ? -36.539 69.495  54.905  1    108.35 ? 104 HIS B CA  1 -0.335 0.637  0.137  
ATOM   3806  C  C   . HIS B 1 115 ? -36.462 68.105  55.521  1    106.79 ? 104 HIS B C   1 -0.334 0.624  0.139  
ATOM   3807  O  O   . HIS B 1 115 ? -35.39  67.482  55.55   1    100.4  ? 104 HIS B O   1 -0.324 0.618  0.139  
ATOM   3808  C  CB  . HIS B 1 115 ? -36.601 70.55   56.011  1    107.48 ? 104 HIS B CB  1 -0.335 0.647  0.14   
ATOM   3809  C  CG  . HIS B 1 115 ? -35.426 70.507  56.941  1    110.9  ? 104 HIS B CG  1 -0.325 0.646  0.142  
ATOM   3810  N  ND1 . HIS B 1 115 ? -35.404 69.728  58.081  1    116.79 ? 104 HIS B ND1 1 -0.324 0.639  0.145  
ATOM   3811  C  CD2 . HIS B 1 115 ? -34.229 71.136  56.893  1    106.8  ? 104 HIS B CD2 1 -0.314 0.652  0.142  
ATOM   3812  C  CE1 . HIS B 1 115 ? -34.243 69.88   58.693  1    115.09 ? 104 HIS B CE1 1 -0.314 0.64   0.147  
ATOM   3813  N  NE2 . HIS B 1 115 ? -33.511 70.728  57.99   1    112.42 ? 104 HIS B NE2 1 -0.307 0.648  0.145  
ATOM   3814  N  N   . LEU B 1 116 ? -37.602 67.593  55.981  1    105.16 ? 105 LEU B N   1 -0.345 0.619  0.14   
ATOM   3815  C  CA  . LEU B 1 116 ? -37.678 66.313  56.664  1    107.06 ? 105 LEU B CA  1 -0.345 0.608  0.141  
ATOM   3816  C  C   . LEU B 1 116 ? -37.653 65.106  55.723  1    105.55 ? 105 LEU B C   1 -0.345 0.597  0.139  
ATOM   3817  O  O   . LEU B 1 116 ? -37.714 63.97   56.213  1    105.78 ? 105 LEU B O   1 -0.346 0.586  0.14   
ATOM   3818  C  CB  . LEU B 1 116 ? -38.944 66.278  57.536  1    111.32 ? 105 LEU B CB  1 -0.357 0.607  0.144  
ATOM   3819  C  CG  . LEU B 1 116 ? -38.825 66.602  59.04   1    103.22 ? 105 LEU B CG  1 -0.356 0.61   0.147  
ATOM   3820  C  CD1 . LEU B 1 116 ? -37.389 66.935  59.465  1    94.28  ? 105 LEU B CD1 1 -0.343 0.613  0.148  
ATOM   3821  C  CD2 . LEU B 1 116 ? -39.787 67.718  59.439  1    103.82 ? 105 LEU B CD2 1 -0.365 0.621  0.148  
ATOM   3822  N  N   . LEU B 1 117 ? -37.558 65.297  54.405  1    107.79 ? 106 LEU B N   1 -0.344 0.598  0.136  
ATOM   3823  C  CA  . LEU B 1 117 ? -37.47  64.142  53.515  1    104.52 ? 106 LEU B CA  1 -0.343 0.588  0.134  
ATOM   3824  C  C   . LEU B 1 117 ? -36.16  63.389  53.757  1    101.37 ? 106 LEU B C   1 -0.331 0.581  0.134  
ATOM   3825  O  O   . LEU B 1 117 ? -35.125 64.004  54.037  1    104.2  ? 106 LEU B O   1 -0.322 0.587  0.135  
ATOM   3826  C  CB  . LEU B 1 117 ? -37.561 64.557  52.047  1    106.06 ? 106 LEU B CB  1 -0.344 0.592  0.13   
ATOM   3827  C  CG  . LEU B 1 117 ? -38.812 65.233  51.493  1    104.14 ? 106 LEU B CG  1 -0.356 0.598  0.129  
ATOM   3828  C  CD1 . LEU B 1 117 ? -38.815 65.103  49.964  1    102.41 ? 106 LEU B CD1 1 -0.356 0.597  0.125  
ATOM   3829  C  CD2 . LEU B 1 117 ? -40.087 64.674  52.162  1    108.64 ? 106 LEU B CD2 1 -0.367 0.593  0.13   
ATOM   3830  N  N   . PRO B 1 118 ? -36.177 62.061  53.673  1    96.74  ? 107 PRO B N   1 -0.332 0.569  0.134  
ATOM   3831  C  CA  . PRO B 1 118 ? -34.992 61.28   54.055  1    100.24 ? 107 PRO B CA  1 -0.321 0.562  0.135  
ATOM   3832  C  C   . PRO B 1 118 ? -33.796 61.625  53.188  1    109.52 ? 107 PRO B C   1 -0.31  0.565  0.133  
ATOM   3833  O  O   . PRO B 1 118 ? -33.887 61.694  51.961  1    111.21 ? 107 PRO B O   1 -0.311 0.565  0.13   
ATOM   3834  C  CB  . PRO B 1 118 ? -35.433 59.823  53.848  1    97.66  ? 107 PRO B CB  1 -0.325 0.548  0.134  
ATOM   3835  C  CG  . PRO B 1 118 ? -36.93  59.871  53.847  1    100.23 ? 107 PRO B CG  1 -0.338 0.549  0.134  
ATOM   3836  C  CD  . PRO B 1 118 ? -37.319 61.21   53.308  1    102.49 ? 107 PRO B CD  1 -0.342 0.561  0.133  
ATOM   3837  N  N   . GLN B 1 119 ? -32.656 61.835  53.849  1    108.42 ? 108 GLN B N   1 -0.299 0.567  0.134  
ATOM   3838  C  CA  . GLN B 1 119 ? -31.428 62.136  53.127  1    116.11 ? 108 GLN B CA  1 -0.288 0.569  0.133  
ATOM   3839  C  C   . GLN B 1 119 ? -30.995 61      52.206  1    112.96 ? 108 GLN B C   1 -0.284 0.559  0.13   
ATOM   3840  O  O   . GLN B 1 119 ? -30.031 61.17   51.449  1    107.04 ? 108 GLN B O   1 -0.275 0.561  0.128  
ATOM   3841  C  CB  . GLN B 1 119 ? -30.322 62.471  54.124  1    114.95 ? 108 GLN B CB  1 -0.278 0.572  0.135  
ATOM   3842  C  CG  . GLN B 1 119 ? -30.438 63.884  54.661  1    117.4  ? 108 GLN B CG  1 -0.279 0.585  0.136  
ATOM   3843  C  CD  . GLN B 1 119 ? -29.328 64.227  55.63   1    124.62 ? 108 GLN B CD  1 -0.269 0.589  0.139  
ATOM   3844  O  OE1 . GLN B 1 119 ? -28.155 63.92   55.388  1    124.41 ? 108 GLN B OE1 1 -0.258 0.586  0.138  
ATOM   3845  N  NE2 . GLN B 1 119 ? -29.692 64.861  56.744  1    130.1  ? 108 GLN B NE2 1 -0.272 0.594  0.142  
ATOM   3846  N  N   . ASP B 1 120 ? -31.689 59.864  52.233  1    111.65 ? 109 ASP B N   1 -0.29  0.549  0.13   
ATOM   3847  C  CA  . ASP B 1 120 ? -31.319 58.685  51.469  1    106.24 ? 109 ASP B CA  1 -0.287 0.538  0.129  
ATOM   3848  C  C   . ASP B 1 120 ? -32.065 58.581  50.151  1    118.19 ? 109 ASP B C   1 -0.294 0.537  0.125  
ATOM   3849  O  O   . ASP B 1 120 ? -31.454 58.172  49.151  1    125.72 ? 109 ASP B O   1 -0.288 0.533  0.123  
ATOM   3850  C  CB  . ASP B 1 120 ? -31.587 57.424  52.286  1    122.43 ? 109 ASP B CB  1 -0.289 0.526  0.131  
ATOM   3851  C  CG  . ASP B 1 120 ? -30.983 56.165  51.663  1    140.26 ? 109 ASP B CG  1 -0.284 0.515  0.129  
ATOM   3852  O  OD1 . ASP B 1 120 ? -30.297 55.417  52.396  1    147.82 ? 109 ASP B OD1 1 -0.278 0.508  0.131  
ATOM   3853  O  OD2 . ASP B 1 120 ? -31.189 55.914  50.455  1    144.91 ? 109 ASP B OD2 1 -0.286 0.512  0.126  
ATOM   3854  N  N   . ASP B 1 121 ? -33.375 58.891  50.141  1    110.68 ? 110 ASP B N   1 -0.306 0.54   0.125  
ATOM   3855  C  CA  . ASP B 1 121 ? -34.243 58.821  48.959  1    112.29 ? 110 ASP B CA  1 -0.314 0.539  0.122  
ATOM   3856  C  C   . ASP B 1 121 ? -33.465 59.12   47.681  1    110.31 ? 110 ASP B C   1 -0.307 0.542  0.119  
ATOM   3857  O  O   . ASP B 1 121 ? -32.762 60.135  47.594  1    106.76 ? 110 ASP B O   1 -0.3   0.551  0.119  
ATOM   3858  C  CB  . ASP B 1 121 ? -35.43  59.781  49.1    1    109.52 ? 110 ASP B CB  1 -0.325 0.548  0.123  
ATOM   3859  C  CG  . ASP B 1 121 ? -36.188 59.979  47.793  1    107.71 ? 110 ASP B CG  1 -0.332 0.55   0.119  
ATOM   3860  O  OD1 . ASP B 1 121 ? -37.359 59.5    47.697  1    107.83 ? 110 ASP B OD1 1 -0.342 0.545  0.119  
ATOM   3861  O  OD2 . ASP B 1 121 ? -35.605 60.628  46.89   1    105.19 ? 110 ASP B OD2 1 -0.326 0.556  0.117  
ATOM   3862  N  N   . ILE B 1 122 ? -33.62  58.232  46.689  1    111.31 ? 111 ILE B N   1 -0.308 0.534  0.117  
ATOM   3863  C  CA  . ILE B 1 122 ? -32.825 58.271  45.459  1    111.22 ? 111 ILE B CA  1 -0.301 0.534  0.114  
ATOM   3864  C  C   . ILE B 1 122 ? -32.858 59.659  44.829  1    107.72 ? 111 ILE B C   1 -0.301 0.547  0.112  
ATOM   3865  O  O   . ILE B 1 122 ? -31.809 60.241  44.522  1    106.14 ? 111 ILE B O   1 -0.292 0.552  0.111  
ATOM   3866  C  CB  . ILE B 1 122 ? -33.32  57.194  44.477  1    108.96 ? 111 ILE B CB  1 -0.305 0.524  0.111  
ATOM   3867  C  CG1 . ILE B 1 122 ? -32.912 55.807  44.961  1    109.84 ? 111 ILE B CG1 1 -0.302 0.511  0.112  
ATOM   3868  C  CG2 . ILE B 1 122 ? -32.757 57.437  43.084  1    112.64 ? 111 ILE B CG2 1 -0.3   0.526  0.108  
ATOM   3869  C  CD1 . ILE B 1 122 ? -31.446 55.547  44.807  1    112.61 ? 111 ILE B CD1 1 -0.288 0.509  0.112  
ATOM   3870  N  N   . ILE B 1 123 ? -34.068 60.204  44.62   1    103.63 ? 112 ILE B N   1 -0.312 0.552  0.111  
ATOM   3871  C  CA  . ILE B 1 123 ? -34.256 61.569  44.126  1    103.26 ? 112 ILE B CA  1 -0.314 0.564  0.11   
ATOM   3872  C  C   . ILE B 1 123 ? -33.46  62.565  44.961  1    106.45 ? 112 ILE B C   1 -0.307 0.573  0.112  
ATOM   3873  O  O   . ILE B 1 123 ? -32.521 63.198  44.464  1    107.67 ? 112 ILE B O   1 -0.298 0.579  0.111  
ATOM   3874  C  CB  . ILE B 1 123 ? -35.732 62.02   44.148  1    95.5   ? 112 ILE B CB  1 -0.327 0.568  0.11   
ATOM   3875  C  CG1 . ILE B 1 123 ? -36.667 61.069  43.422  1    88.65  ? 112 ILE B CG1 1 -0.336 0.56   0.108  
ATOM   3876  C  CG2 . ILE B 1 123 ? -35.844 63.44   43.597  1    94.42  ? 112 ILE B CG2 1 -0.328 0.581  0.109  
ATOM   3877  C  CD1 . ILE B 1 123 ? -38.019 61.701  43.165  1    90.76  ? 112 ILE B CD1 1 -0.348 0.565  0.108  
ATOM   3878  N  N   . LEU B 1 124 ? -33.871 62.746  46.223  1    102.12 ? 113 LEU B N   1 -0.31  0.575  0.115  
ATOM   3879  C  CA  . LEU B 1 124 ? -33.409 63.898  46.986  1    102.18 ? 113 LEU B CA  1 -0.306 0.586  0.117  
ATOM   3880  C  C   . LEU B 1 124 ? -31.889 63.946  47.055  1    101.92 ? 113 LEU B C   1 -0.292 0.586  0.117  
ATOM   3881  O  O   . LEU B 1 124 ? -31.277 64.987  46.787  1    98.16  ? 113 LEU B O   1 -0.287 0.596  0.117  
ATOM   3882  C  CB  . LEU B 1 124 ? -34.012 63.878  48.389  1    107.04 ? 113 LEU B CB  1 -0.312 0.585  0.121  
ATOM   3883  C  CG  . LEU B 1 124 ? -33.683 65.094  49.264  1    106.5  ? 113 LEU B CG  1 -0.309 0.597  0.123  
ATOM   3884  C  CD1 . LEU B 1 124 ? -34.897 65.42   50.074  1    109.16 ? 113 LEU B CD1 1 -0.32  0.6    0.125  
ATOM   3885  C  CD2 . LEU B 1 124 ? -32.47  64.864  50.186  1    98.61  ? 113 LEU B CD2 1 -0.298 0.594  0.125  
ATOM   3886  N  N   . ARG B 1 125 ? -31.26  62.823  47.405  1    104.53 ? 114 ARG B N   1 -0.286 0.576  0.118  
ATOM   3887  C  CA  . ARG B 1 125 ? -29.812 62.816  47.55   1    105.06 ? 114 ARG B CA  1 -0.273 0.576  0.119  
ATOM   3888  C  C   . ARG B 1 125 ? -29.114 63.302  46.286  1    106.02 ? 114 ARG B C   1 -0.267 0.58   0.116  
ATOM   3889  O  O   . ARG B 1 125 ? -27.981 63.781  46.371  1    112.61 ? 114 ARG B O   1 -0.256 0.584  0.116  
ATOM   3890  C  CB  . ARG B 1 125 ? -29.321 61.417  47.937  1    105.69 ? 114 ARG B CB  1 -0.269 0.563  0.12   
ATOM   3891  C  CG  . ARG B 1 125 ? -28.81  60.584  46.767  1    111.37 ? 114 ARG B CG  1 -0.264 0.555  0.117  
ATOM   3892  C  CD  . ARG B 1 125 ? -28.961 59.1    47.052  1    115.39 ? 114 ARG B CD  1 -0.265 0.542  0.117  
ATOM   3893  N  NE  . ARG B 1 125 ? -28.101 58.283  46.203  1    116.54 ? 114 ARG B NE  1 -0.258 0.534  0.115  
ATOM   3894  C  CZ  . ARG B 1 125 ? -28.147 56.959  46.131  1    118.25 ? 114 ARG B CZ  1 -0.258 0.522  0.115  
ATOM   3895  N  NH1 . ARG B 1 125 ? -29.045 56.26   46.806  1    124.35 ? 114 ARG B NH1 1 -0.266 0.516  0.117  
ATOM   3896  N  NH2 . ARG B 1 125 ? -27.267 56.317  45.364  1    119.52 ? 114 ARG B NH2 1 -0.25  0.516  0.113  
ATOM   3897  N  N   . ALA B 1 126 ? -29.77  63.218  45.123  1    107.47 ? 115 ALA B N   1 -0.273 0.579  0.113  
ATOM   3898  C  CA  . ALA B 1 126 ? -29.256 63.81   43.886  1    103.97 ? 115 ALA B CA  1 -0.268 0.585  0.11   
ATOM   3899  C  C   . ALA B 1 126 ? -29.74  65.248  43.695  1    98.86  ? 115 ALA B C   1 -0.273 0.598  0.109  
ATOM   3900  O  O   . ALA B 1 126 ? -28.937 66.144  43.395  1    95.57  ? 115 ALA B O   1 -0.265 0.606  0.108  
ATOM   3901  C  CB  . ALA B 1 126 ? -29.664 62.952  42.679  1    97.49  ? 115 ALA B CB  1 -0.272 0.577  0.107  
ATOM   3902  N  N   . LEU B 1 127 ? -31.055 65.462  43.855  1    95.38  ? 116 LEU B N   1 -0.285 0.6    0.109  
ATOM   3903  C  CA  . LEU B 1 127 ? -31.636 66.804  43.835  1    95.38  ? 116 LEU B CA  1 -0.29  0.612  0.109  
ATOM   3904  C  C   . LEU B 1 127 ? -30.807 67.768  44.672  1    99.9   ? 116 LEU B C   1 -0.282 0.621  0.112  
ATOM   3905  O  O   . LEU B 1 127 ? -30.475 68.871  44.223  1    103.17 ? 116 LEU B O   1 -0.279 0.631  0.11   
ATOM   3906  C  CB  . LEU B 1 127 ? -33.09  66.734  44.336  1    90.94  ? 116 LEU B CB  1 -0.303 0.612  0.111  
ATOM   3907  C  CG  . LEU B 1 127 ? -34.061 67.921  44.345  1    76.31  ? 116 LEU B CG  1 -0.312 0.622  0.111  
ATOM   3908  C  CD1 . LEU B 1 127 ? -33.964 68.619  45.622  1    107.21 ? 116 LEU B CD1 1 -0.311 0.629  0.114  
ATOM   3909  C  CD2 . LEU B 1 127 ? -33.72  68.894  43.238  1    100.88 ? 116 LEU B CD2 1 -0.309 0.631  0.108  
ATOM   3910  N  N   . ARG B 1 128 ? -30.387 67.325  45.857  1    103.24 ? 117 ARG B N   1 -0.278 0.617  0.114  
ATOM   3911  C  CA  . ARG B 1 128 ? -29.7   68.164  46.828  1    103.83 ? 117 ARG B CA  1 -0.272 0.625  0.117  
ATOM   3912  C  C   . ARG B 1 128 ? -28.192 68.207  46.66   1    101.92 ? 117 ARG B C   1 -0.258 0.625  0.117  
ATOM   3913  O  O   . ARG B 1 128 ? -27.552 69.078  47.258  1    104.8  ? 117 ARG B O   1 -0.252 0.633  0.118  
ATOM   3914  C  CB  . ARG B 1 128 ? -30.018 67.688  48.23   1    105.61 ? 117 ARG B CB  1 -0.275 0.62   0.12   
ATOM   3915  C  CG  . ARG B 1 128 ? -31.244 68.344  48.788  1    111.7  ? 117 ARG B CG  1 -0.286 0.626  0.122  
ATOM   3916  C  CD  . ARG B 1 128 ? -30.87  69.092  50.032  1    120.75 ? 117 ARG B CD  1 -0.283 0.633  0.125  
ATOM   3917  N  NE  . ARG B 1 128 ? -30.031 70.247  49.747  1    121.18 ? 117 ARG B NE  1 -0.275 0.644  0.124  
ATOM   3918  C  CZ  . ARG B 1 128 ? -29.031 70.646  50.519  1    125.28 ? 117 ARG B CZ  1 -0.266 0.647  0.126  
ATOM   3919  N  NH1 . ARG B 1 128 ? -28.693 69.984  51.611  1    125.74 ? 117 ARG B NH1 1 -0.263 0.641  0.129  
ATOM   3920  N  NH2 . ARG B 1 128 ? -28.353 71.742  50.191  1    127.42 ? 117 ARG B NH2 1 -0.26  0.657  0.125  
ATOM   3921  N  N   . ALA B 1 129 ? -27.61  67.289  45.894  1    100.21 ? 118 ALA B N   1 -0.253 0.617  0.115  
ATOM   3922  C  CA  . ALA B 1 129 ? -26.199 67.374  45.541  1    100.53 ? 118 ALA B CA  1 -0.24  0.617  0.114  
ATOM   3923  C  C   . ALA B 1 129 ? -25.932 68.28   44.336  1    106.14 ? 118 ALA B C   1 -0.238 0.626  0.111  
ATOM   3924  O  O   . ALA B 1 129 ? -24.761 68.568  44.049  1    103.94 ? 118 ALA B O   1 -0.227 0.628  0.11   
ATOM   3925  C  CB  . ALA B 1 129 ? -25.636 65.98   45.26   1    98.95  ? 118 ALA B CB  1 -0.235 0.605  0.113  
ATOM   3926  N  N   . VAL B 1 130 ? -26.953 68.742  43.613  1    92.67  ? 119 VAL B N   1 -0.247 0.63   0.109  
ATOM   3927  C  CA  . VAL B 1 130 ? -26.692 69.762  42.611  1    98.17  ? 119 VAL B CA  1 -0.245 0.639  0.106  
ATOM   3928  C  C   . VAL B 1 130 ? -27.361 71.093  42.917  1    99.79  ? 119 VAL B C   1 -0.251 0.652  0.107  
ATOM   3929  O  O   . VAL B 1 130 ? -26.854 72.132  42.457  1    103.54 ? 119 VAL B O   1 -0.246 0.661  0.106  
ATOM   3930  C  CB  . VAL B 1 130 ? -27.046 69.277  41.18   1    103.94 ? 119 VAL B CB  1 -0.248 0.635  0.103  
ATOM   3931  C  CG1 . VAL B 1 130 ? -26.552 67.839  40.967  1    94.28  ? 119 VAL B CG1 1 -0.243 0.622  0.102  
ATOM   3932  C  CG2 . VAL B 1 130 ? -28.539 69.45   40.83   1    100.98 ? 119 VAL B CG2 1 -0.262 0.636  0.102  
ATOM   3933  N  N   . HIS B 1 131 ? -28.428 71.142  43.712  1    98.72  ? 120 HIS B N   1 -0.261 0.652  0.109  
ATOM   3934  C  CA  . HIS B 1 131 ? -29.015 72.415  44.113  1    104.86 ? 120 HIS B CA  1 -0.266 0.664  0.11   
ATOM   3935  C  C   . HIS B 1 131 ? -29.019 72.607  45.622  1    108.52 ? 120 HIS B C   1 -0.266 0.665  0.114  
ATOM   3936  O  O   . HIS B 1 131 ? -29.201 71.656  46.389  1    109.29 ? 120 HIS B O   1 -0.268 0.657  0.116  
ATOM   3937  C  CB  . HIS B 1 131 ? -30.426 72.551  43.604  1    107.9  ? 120 HIS B CB  1 -0.279 0.665  0.109  
ATOM   3938  C  CG  . HIS B 1 131 ? -30.503 72.548  42.117  1    106.53 ? 120 HIS B CG  1 -0.28  0.665  0.105  
ATOM   3939  N  ND1 . HIS B 1 131 ? -29.952 73.55   41.346  1    106.35 ? 120 HIS B ND1 1 -0.274 0.674  0.103  
ATOM   3940  C  CD2 . HIS B 1 131 ? -31.043 71.657  41.258  1    99.21  ? 120 HIS B CD2 1 -0.284 0.657  0.103  
ATOM   3941  C  CE1 . HIS B 1 131 ? -30.162 73.28   40.073  1    98.37  ? 120 HIS B CE1 1 -0.276 0.672  0.1    
ATOM   3942  N  NE2 . HIS B 1 131 ? -30.815 72.136  39.993  1    100.03 ? 120 HIS B NE2 1 -0.282 0.661  0.1    
ATOM   3943  N  N   . SER B 1 132 ? -28.854 73.869  46.033  1    118.4  ? 121 SER B N   1 -0.264 0.677  0.115  
ATOM   3944  C  CA  . SER B 1 132 ? -28.761 74.241  47.445  1    115.57 ? 121 SER B CA  1 -0.264 0.68   0.118  
ATOM   3945  C  C   . SER B 1 132 ? -30.141 74.354  48.08   1    114.03 ? 121 SER B C   1 -0.276 0.681  0.12   
ATOM   3946  O  O   . SER B 1 132 ? -31.101 74.794  47.439  1    113    ? 121 SER B O   1 -0.285 0.685  0.118  
ATOM   3947  C  CB  . SER B 1 132 ? -28.045 75.586  47.603  1    115.09 ? 121 SER B CB  1 -0.257 0.693  0.119  
ATOM   3948  O  OG  . SER B 1 132 ? -28.923 76.671  47.311  1    108.74 ? 121 SER B OG  1 -0.265 0.703  0.118  
ATOM   3949  N  N   . GLU B 1 133 ? -30.222 73.972  49.362  1    118.3  ? 122 GLU B N   1 -0.277 0.678  0.123  
ATOM   3950  C  CA  . GLU B 1 133 ? -31.442 74.149  50.141  1    116.98 ? 122 GLU B CA  1 -0.288 0.68   0.125  
ATOM   3951  C  C   . GLU B 1 133 ? -32.129 75.473  49.836  1    113.68 ? 122 GLU B C   1 -0.294 0.692  0.124  
ATOM   3952  O  O   . GLU B 1 133 ? -33.324 75.508  49.52   1    105.53 ? 122 GLU B O   1 -0.305 0.692  0.124  
ATOM   3953  C  CB  . GLU B 1 133 ? -31.115 74.076  51.63   1    126.73 ? 122 GLU B CB  1 -0.285 0.679  0.129  
ATOM   3954  C  CG  . GLU B 1 133 ? -30.868 72.686  52.149  1    140.44 ? 122 GLU B CG  1 -0.283 0.666  0.13   
ATOM   3955  C  CD  . GLU B 1 133 ? -32.146 71.889  52.421  1    138.14 ? 122 GLU B CD  1 -0.295 0.659  0.131  
ATOM   3956  O  OE1 . GLU B 1 133 ? -33.007 72.381  53.252  1    120.74 ? 122 GLU B OE1 1 -0.302 0.663  0.133  
ATOM   3957  O  OE2 . GLU B 1 133 ? -32.255 70.786  51.825  1    131.03 ? 122 GLU B OE2 1 -0.296 0.649  0.129  
ATOM   3958  N  N   . ASP B 1 134 ? -31.37  76.574  49.91   1    114.38 ? 123 ASP B N   1 -0.287 0.702  0.125  
ATOM   3959  C  CA  . ASP B 1 134 ? -31.957 77.901  49.745  1    115.55 ? 123 ASP B CA  1 -0.293 0.714  0.124  
ATOM   3960  C  C   . ASP B 1 134 ? -32.713 77.996  48.431  1    115.01 ? 123 ASP B C   1 -0.3   0.715  0.121  
ATOM   3961  O  O   . ASP B 1 134 ? -33.85  78.482  48.391  1    111.75 ? 123 ASP B O   1 -0.31  0.719  0.121  
ATOM   3962  C  CB  . ASP B 1 134 ? -30.868 78.978  49.825  1    125.86 ? 123 ASP B CB  1 -0.283 0.724  0.124  
ATOM   3963  C  CG  . ASP B 1 134 ? -30.661 79.512  51.258  1    130.12 ? 123 ASP B CG  1 -0.281 0.729  0.128  
ATOM   3964  O  OD1 . ASP B 1 134 ? -31.43  79.112  52.164  1    126.91 ? 123 ASP B OD1 1 -0.288 0.725  0.13   
ATOM   3965  O  OD2 . ASP B 1 134 ? -29.729 80.336  51.475  1    127.6  ? 123 ASP B OD2 1 -0.272 0.736  0.129  
ATOM   3966  N  N   . TYR B 1 135 ? -32.108 77.497  47.348  1    115.83 ? 124 TYR B N   1 -0.294 0.71   0.118  
ATOM   3967  C  CA  . TYR B 1 135 ? -32.769 77.528  46.047  1    111.39 ? 124 TYR B CA  1 -0.3   0.71   0.115  
ATOM   3968  C  C   . TYR B 1 135 ? -34.063 76.718  46.076  1    107.21 ? 124 TYR B C   1 -0.312 0.703  0.115  
ATOM   3969  O  O   . TYR B 1 135 ? -35.151 77.258  45.85   1    105.33 ? 124 TYR B O   1 -0.322 0.708  0.114  
ATOM   3970  C  CB  . TYR B 1 135 ? -31.811 77.023  44.955  1    109.34 ? 124 TYR B CB  1 -0.292 0.706  0.112  
ATOM   3971  C  CG  . TYR B 1 135 ? -32.392 77.083  43.547  1    113.03 ? 124 TYR B CG  1 -0.297 0.706  0.109  
ATOM   3972  C  CD1 . TYR B 1 135 ? -33.414 77.983  43.22   1    113.71 ? 124 TYR B CD1 1 -0.306 0.715  0.108  
ATOM   3973  C  CD2 . TYR B 1 135 ? -31.935 76.229  42.549  1    111.11 ? 124 TYR B CD2 1 -0.293 0.699  0.106  
ATOM   3974  C  CE1 . TYR B 1 135 ? -33.955 78.024  41.945  1    105.49 ? 124 TYR B CE1 1 -0.311 0.715  0.105  
ATOM   3975  C  CE2 . TYR B 1 135 ? -32.473 76.273  41.267  1    109.48 ? 124 TYR B CE2 1 -0.298 0.699  0.103  
ATOM   3976  C  CZ  . TYR B 1 135 ? -33.48  77.171  40.985  1    105.84 ? 124 TYR B CZ  1 -0.307 0.707  0.102  
ATOM   3977  O  OH  . TYR B 1 135 ? -34.01  77.218  39.725  1    116.32 ? 124 TYR B OH  1 -0.312 0.708  0.099  
ATOM   3978  N  N   . LEU B 1 136 ? -33.966 75.42   46.375  1    100.7  ? 125 LEU B N   1 -0.311 0.691  0.116  
ATOM   3979  C  CA  . LEU B 1 136 ? -35.162 74.585  46.433  1    97.46  ? 125 LEU B CA  1 -0.322 0.684  0.116  
ATOM   3980  C  C   . LEU B 1 136 ? -36.19  75.158  47.393  1    105.65 ? 125 LEU B C   1 -0.332 0.689  0.118  
ATOM   3981  O  O   . LEU B 1 136 ? -37.394 75.136  47.109  1    93.52  ? 125 LEU B O   1 -0.343 0.689  0.118  
ATOM   3982  C  CB  . LEU B 1 136 ? -34.776 73.172  46.843  1    99.42  ? 125 LEU B CB  1 -0.319 0.671  0.117  
ATOM   3983  C  CG  . LEU B 1 136 ? -33.512 72.775  46.092  1    107.85 ? 125 LEU B CG  1 -0.307 0.667  0.115  
ATOM   3984  C  CD1 . LEU B 1 136 ? -32.806 71.631  46.782  1    112.43 ? 125 LEU B CD1 1 -0.301 0.656  0.117  
ATOM   3985  C  CD2 . LEU B 1 136 ? -33.867 72.415  44.666  1    105.31 ? 125 LEU B CD2 1 -0.31  0.664  0.112  
ATOM   3986  N  N   . TYR B 1 137 ? -35.727 75.662  48.549  1    118.24 ? 126 TYR B N   1 -0.327 0.693  0.121  
ATOM   3987  C  CA  . TYR B 1 137 ? -36.62  76.331  49.49   1    110.2  ? 126 TYR B CA  1 -0.336 0.7    0.124  
ATOM   3988  C  C   . TYR B 1 137 ? -37.348 77.49   48.807  1    112.42 ? 126 TYR B C   1 -0.342 0.71   0.122  
ATOM   3989  O  O   . TYR B 1 137 ? -38.576 77.605  48.893  1    108.38 ? 126 TYR B O   1 -0.354 0.711  0.122  
ATOM   3990  C  CB  . TYR B 1 137 ? -35.833 76.816  50.71   1    111.84 ? 126 TYR B CB  1 -0.328 0.704  0.127  
ATOM   3991  C  CG  . TYR B 1 137 ? -36.031 76.012  52.002  1    124.37 ? 126 TYR B CG  1 -0.33  0.697  0.13   
ATOM   3992  C  CD1 . TYR B 1 137 ? -35.82  74.633  52.035  1    124.6  ? 126 TYR B CD1 1 -0.328 0.684  0.13   
ATOM   3993  C  CD2 . TYR B 1 137 ? -36.402 76.634  53.194  1    113.59 ? 126 TYR B CD2 1 -0.334 0.702  0.133  
ATOM   3994  C  CE1 . TYR B 1 137 ? -35.983 73.898  53.208  1    112.05 ? 126 TYR B CE1 1 -0.33  0.677  0.133  
ATOM   3995  C  CE2 . TYR B 1 137 ? -36.575 75.897  54.351  1    115.67 ? 126 TYR B CE2 1 -0.335 0.696  0.136  
ATOM   3996  C  CZ  . TYR B 1 137 ? -36.362 74.523  54.357  1    116.85 ? 126 TYR B CZ  1 -0.333 0.683  0.136  
ATOM   3997  O  OH  . TYR B 1 137 ? -36.519 73.755  55.506  1    116.63 ? 126 TYR B OH  1 -0.335 0.676  0.139  
ATOM   3998  N  N   . GLN B 1 138 ? -36.611 78.342  48.09   1    109.45 ? 127 GLN B N   1 -0.336 0.718  0.12   
ATOM   3999  C  CA  . GLN B 1 138 ? -37.265 79.455  47.411  1    109.7  ? 127 GLN B CA  1 -0.342 0.728  0.118  
ATOM   4000  C  C   . GLN B 1 138 ? -38.078 78.994  46.202  1    111.95 ? 127 GLN B C   1 -0.349 0.724  0.115  
ATOM   4001  O  O   . GLN B 1 138 ? -39.01  79.696  45.786  1    109.09 ? 127 GLN B O   1 -0.357 0.73   0.114  
ATOM   4002  C  CB  . GLN B 1 138 ? -36.227 80.503  46.993  1    112.18 ? 127 GLN B CB  1 -0.332 0.738  0.117  
ATOM   4003  C  CG  . GLN B 1 138 ? -35.694 80.329  45.582  1    119.51 ? 127 GLN B CG  1 -0.327 0.736  0.114  
ATOM   4004  C  CD  . GLN B 1 138 ? -34.727 81.424  45.163  1    125.33 ? 127 GLN B CD  1 -0.318 0.746  0.113  
ATOM   4005  O  OE1 . GLN B 1 138 ? -34.932 82.093  44.133  1    123.82 ? 127 GLN B OE1 1 -0.32  0.752  0.11   
ATOM   4006  N  NE2 . GLN B 1 138 ? -33.652 81.605  45.947  1    121.27 ? 127 GLN B NE2 1 -0.308 0.748  0.115  
ATOM   4007  N  N   . LEU B 1 139 ? -37.752 77.83   45.631  1    111.02 ? 128 LEU B N   1 -0.346 0.713  0.114  
ATOM   4008  C  CA  . LEU B 1 139 ? -38.492 77.328  44.474  1    105.86 ? 128 LEU B CA  1 -0.353 0.709  0.111  
ATOM   4009  C  C   . LEU B 1 139 ? -39.899 76.907  44.875  1    105    ? 128 LEU B C   1 -0.366 0.705  0.112  
ATOM   4010  O  O   . LEU B 1 139 ? -40.888 77.363  44.287  1    103.44 ? 128 LEU B O   1 -0.375 0.709  0.111  
ATOM   4011  C  CB  . LEU B 1 139 ? -37.732 76.161  43.847  1    106.83 ? 128 LEU B CB  1 -0.346 0.698  0.109  
ATOM   4012  C  CG  . LEU B 1 139 ? -38.122 75.546  42.507  1    103.03 ? 128 LEU B CG  1 -0.349 0.692  0.106  
ATOM   4013  C  CD1 . LEU B 1 139 ? -38.253 76.618  41.42   1    98.74  ? 128 LEU B CD1 1 -0.351 0.702  0.103  
ATOM   4014  C  CD2 . LEU B 1 139 ? -37.04  74.549  42.161  1    100.01 ? 128 LEU B CD2 1 -0.339 0.683  0.105  
ATOM   4015  N  N   . ILE B 1 140 ? -40     76.045  45.895  1    109.85 ? 129 ILE B N   1 -0.367 0.697  0.115  
ATOM   4016  C  CA  . ILE B 1 140 ? -41.297 75.653  46.444  1    105.56 ? 129 ILE B CA  1 -0.378 0.693  0.116  
ATOM   4017  C  C   . ILE B 1 140 ? -42.065 76.869  46.931  1    106.29 ? 129 ILE B C   1 -0.385 0.704  0.117  
ATOM   4018  O  O   . ILE B 1 140 ? -43.302 76.858  46.981  1    106.97 ? 129 ILE B O   1 -0.397 0.704  0.117  
ATOM   4019  C  CB  . ILE B 1 140 ? -41.108 74.626  47.57   1    101.38 ? 129 ILE B CB  1 -0.377 0.684  0.119  
ATOM   4020  C  CG1 . ILE B 1 140 ? -40.115 73.547  47.14   1    98.89  ? 129 ILE B CG1 1 -0.368 0.674  0.118  
ATOM   4021  C  CG2 . ILE B 1 140 ? -42.453 74.01   47.954  1    105.15 ? 129 ILE B CG2 1 -0.389 0.678  0.12   
ATOM   4022  C  CD1 . ILE B 1 140 ? -39.752 72.586  48.261  1    107.79 ? 129 ILE B CD1 1 -0.364 0.665  0.12   
ATOM   4023  N  N   . LYS B 1 141 ? -41.355 77.933  47.302  1    107.86 ? 130 LYS B N   1 -0.379 0.714  0.118  
ATOM   4024  C  CA  . LYS B 1 141 ? -42.02  79.189  47.614  1    111.01 ? 130 LYS B CA  1 -0.385 0.726  0.119  
ATOM   4025  C  C   . LYS B 1 141 ? -42.685 79.758  46.369  1    112.69 ? 130 LYS B C   1 -0.391 0.731  0.116  
ATOM   4026  O  O   . LYS B 1 141 ? -43.871 80.112  46.386  1    110.61 ? 130 LYS B O   1 -0.402 0.734  0.116  
ATOM   4027  C  CB  . LYS B 1 141 ? -41.007 80.175  48.199  1    116.87 ? 130 LYS B CB  1 -0.376 0.735  0.12   
ATOM   4028  C  CG  . LYS B 1 141 ? -41.624 81.407  48.849  1    123.21 ? 130 LYS B CG  1 -0.381 0.746  0.122  
ATOM   4029  C  CD  . LYS B 1 141 ? -40.579 82.491  49.102  1    122.38 ? 130 LYS B CD  1 -0.372 0.756  0.123  
ATOM   4030  C  CE  . LYS B 1 141 ? -41.214 83.764  49.665  1    127.65 ? 130 LYS B CE  1 -0.378 0.768  0.124  
ATOM   4031  N  NZ  . LYS B 1 141 ? -40.354 84.942  49.342  1    127.25 ? 130 LYS B NZ  1 -0.37  0.778  0.123  
ATOM   4032  N  N   . TYR B 1 142 ? -41.929 79.815  45.263  1    115.95 ? 131 TYR B N   1 -0.384 0.731  0.113  
ATOM   4033  C  CA  . TYR B 1 142 ? -42.428 80.401  44.025  1    108.43 ? 131 TYR B CA  1 -0.389 0.737  0.11   
ATOM   4034  C  C   . TYR B 1 142 ? -43.594 79.618  43.457  1    107.01 ? 131 TYR B C   1 -0.4   0.73   0.109  
ATOM   4035  O  O   . TYR B 1 142 ? -44.471 80.203  42.812  1    108.34 ? 131 TYR B O   1 -0.408 0.735  0.107  
ATOM   4036  C  CB  . TYR B 1 142 ? -41.319 80.467  42.991  1    105.19 ? 131 TYR B CB  1 -0.379 0.737  0.107  
ATOM   4037  C  CG  . TYR B 1 142 ? -40.335 81.578  43.205  1    113.47 ? 131 TYR B CG  1 -0.37  0.748  0.108  
ATOM   4038  C  CD1 . TYR B 1 142 ? -39.036 81.457  42.737  1    115.42 ? 131 TYR B CD1 1 -0.358 0.746  0.107  
ATOM   4039  C  CD2 . TYR B 1 142 ? -40.69  82.747  43.882  1    122.43 ? 131 TYR B CD2 1 -0.373 0.758  0.11   
ATOM   4040  C  CE1 . TYR B 1 142 ? -38.108 82.463  42.918  1    120.36 ? 131 TYR B CE1 1 -0.349 0.756  0.107  
ATOM   4041  C  CE2 . TYR B 1 142 ? -39.751 83.778  44.077  1    127.32 ? 131 TYR B CE2 1 -0.364 0.768  0.11   
ATOM   4042  C  CZ  . TYR B 1 142 ? -38.46  83.624  43.577  1    124.43 ? 131 TYR B CZ  1 -0.352 0.766  0.109  
ATOM   4043  O  OH  . TYR B 1 142 ? -37.495 84.602  43.724  1    124.59 ? 131 TYR B OH  1 -0.344 0.775  0.109  
ATOM   4044  N  N   . CYS B 1 143 ? -43.613 78.297  43.668  1    104.41 ? 132 CYS B N   1 -0.4   0.718  0.109  
ATOM   4045  C  CA  . CYS B 1 143 ? -44.714 77.486  43.161  1    109.11 ? 132 CYS B CA  1 -0.41  0.71   0.108  
ATOM   4046  C  C   . CYS B 1 143 ? -46.017 77.841  43.859  1    114.36 ? 132 CYS B C   1 -0.422 0.713  0.11   
ATOM   4047  O  O   . CYS B 1 143 ? -47.064 77.978  43.206  1    112    ? 132 CYS B O   1 -0.431 0.715  0.108  
ATOM   4048  C  CB  . CYS B 1 143 ? -44.405 76.005  43.347  1    111.64 ? 132 CYS B CB  1 -0.407 0.697  0.108  
ATOM   4049  S  SG  . CYS B 1 143 ? -43.449 75.284  41.995  1    115.6  ? 132 CYS B SG  1 -0.398 0.69   0.105  
ATOM   4050  N  N   . ILE B 1 144 ? -45.966 77.999  45.183  1    112.84 ? 133 ILE B N   1 -0.421 0.715  0.113  
ATOM   4051  C  CA  . ILE B 1 144 ? -47.173 78.302  45.936  1    111.63 ? 133 ILE B CA  1 -0.432 0.718  0.115  
ATOM   4052  C  C   . ILE B 1 144 ? -47.588 79.752  45.731  1    108.65 ? 133 ILE B C   1 -0.436 0.731  0.114  
ATOM   4053  O  O   . ILE B 1 144 ? -48.786 80.05   45.671  1    114.8  ? 133 ILE B O   1 -0.447 0.734  0.114  
ATOM   4054  C  CB  . ILE B 1 144 ? -46.964 77.941  47.421  1    116.27 ? 133 ILE B CB  1 -0.43  0.714  0.118  
ATOM   4055  C  CG1 . ILE B 1 144 ? -47.001 76.419  47.582  1    116.81 ? 133 ILE B CG1 1 -0.431 0.7    0.119  
ATOM   4056  C  CG2 . ILE B 1 144 ? -48.024 78.59   48.308  1    118.13 ? 133 ILE B CG2 1 -0.44  0.72   0.121  
ATOM   4057  C  CD1 . ILE B 1 144 ? -46.335 75.893  48.832  1    111.66 ? 133 ILE B CD1 1 -0.425 0.695  0.122  
ATOM   4058  N  N   . GLN B 1 145 ? -46.63  80.673  45.583  1    103.54 ? 134 GLN B N   1 -0.427 0.739  0.114  
ATOM   4059  C  CA  . GLN B 1 145 ? -46.995 82.022  45.154  1    110.42 ? 134 GLN B CA  1 -0.431 0.752  0.113  
ATOM   4060  C  C   . GLN B 1 145 ? -47.736 82.025  43.822  1    116.84 ? 134 GLN B C   1 -0.437 0.752  0.109  
ATOM   4061  O  O   . GLN B 1 145 ? -48.495 82.961  43.551  1    115.65 ? 134 GLN B O   1 -0.444 0.76   0.109  
ATOM   4062  C  CB  . GLN B 1 145 ? -45.763 82.909  45.021  1    108.53 ? 134 GLN B CB  1 -0.419 0.76   0.112  
ATOM   4063  C  CG  . GLN B 1 145 ? -44.984 83.088  46.3    1    114.71 ? 134 GLN B CG  1 -0.412 0.761  0.116  
ATOM   4064  C  CD  . GLN B 1 145 ? -44.033 84.266  46.234  1    120.31 ? 134 GLN B CD  1 -0.404 0.772  0.115  
ATOM   4065  O  OE1 . GLN B 1 145 ? -44.33  85.271  45.589  1    120.09 ? 134 GLN B OE1 1 -0.406 0.781  0.114  
ATOM   4066  N  NE2 . GLN B 1 145 ? -42.879 84.148  46.892  1    120.37 ? 134 GLN B NE2 1 -0.393 0.771  0.117  
ATOM   4067  N  N   . ALA B 1 146 ? -47.532 80.999  42.989  1    118.59 ? 135 ALA B N   1 -0.436 0.742  0.107  
ATOM   4068  C  CA  . ALA B 1 146 ? -48.135 80.955  41.665  1    118.55 ? 135 ALA B CA  1 -0.441 0.742  0.104  
ATOM   4069  C  C   . ALA B 1 146 ? -49.621 80.616  41.694  1    122.55 ? 135 ALA B C   1 -0.455 0.739  0.104  
ATOM   4070  O  O   . ALA B 1 146 ? -50.342 80.99   40.76   1    118.42 ? 135 ALA B O   1 -0.461 0.742  0.102  
ATOM   4071  C  CB  . ALA B 1 146 ? -47.394 79.942  40.796  1    116.14 ? 135 ALA B CB  1 -0.434 0.733  0.102  
ATOM   4072  N  N   . LYS B 1 147 ? -50.098 79.945  42.749  1    121.66 ? 136 LYS B N   1 -0.459 0.733  0.107  
ATOM   4073  C  CA  . LYS B 1 147 ? -51.448 79.391  42.757  1    119.73 ? 136 LYS B CA  1 -0.471 0.728  0.107  
ATOM   4074  C  C   . LYS B 1 147 ? -52.536 80.454  42.702  1    122.37 ? 136 LYS B C   1 -0.481 0.737  0.107  
ATOM   4075  O  O   . LYS B 1 147 ? -53.696 80.118  42.43   1    116.14 ? 136 LYS B O   1 -0.492 0.734  0.106  
ATOM   4076  C  CB  . LYS B 1 147 ? -51.637 78.523  43.989  1    119.02 ? 136 LYS B CB  1 -0.473 0.72   0.11   
ATOM   4077  C  CG  . LYS B 1 147 ? -52.897 77.68   43.975  1    127.62 ? 136 LYS B CG  1 -0.485 0.712  0.11   
ATOM   4078  C  CD  . LYS B 1 147 ? -52.943 76.819  45.213  1    122.82 ? 136 LYS B CD  1 -0.485 0.704  0.113  
ATOM   4079  C  CE  . LYS B 1 147 ? -51.666 76.03   45.279  1    122.14 ? 136 LYS B CE  1 -0.473 0.697  0.113  
ATOM   4080  N  NZ  . LYS B 1 147 ? -51.44  75.496  46.62   1    122.11 ? 136 LYS B NZ  1 -0.471 0.692  0.116  
ATOM   4081  N  N   . HIS B 1 148 ? -52.192 81.722  42.937  1    127.44 ? 137 HIS B N   1 -0.478 0.749  0.107  
ATOM   4082  C  CA  . HIS B 1 148 ? -53.19  82.782  42.829  1    135.29 ? 137 HIS B CA  1 -0.487 0.759  0.107  
ATOM   4083  C  C   . HIS B 1 148 ? -53.533 83.058  41.368  1    136.85 ? 137 HIS B C   1 -0.491 0.761  0.103  
ATOM   4084  O  O   . HIS B 1 148 ? -54.71  83.177  41.004  1    138.12 ? 137 HIS B O   1 -0.501 0.762  0.102  
ATOM   4085  C  CB  . HIS B 1 148 ? -52.693 84.054  43.524  1    138.95 ? 137 HIS B CB  1 -0.483 0.77   0.109  
ATOM   4086  C  CG  . HIS B 1 148 ? -53.681 85.186  43.506  1    147.78 ? 137 HIS B CG  1 -0.492 0.781  0.109  
ATOM   4087  N  ND1 . HIS B 1 148 ? -55.016 85.012  43.203  1    147.99 ? 137 HIS B ND1 1 -0.504 0.779  0.108  
ATOM   4088  C  CD2 . HIS B 1 148 ? -53.522 86.51   43.748  1    152.13 ? 137 HIS B CD2 1 -0.49  0.793  0.109  
ATOM   4089  C  CE1 . HIS B 1 148 ? -55.635 86.178  43.257  1    150.98 ? 137 HIS B CE1 1 -0.51  0.79   0.108  
ATOM   4090  N  NE2 . HIS B 1 148 ? -54.752 87.104  43.586  1    155.64 ? 137 HIS B NE2 1 -0.502 0.798  0.109  
ATOM   4091  N  N   . PHE B 1 149 ? -52.523 83.159  40.513  1    133.24 ? 138 PHE B N   1 -0.481 0.762  0.101  
ATOM   4092  C  CA  . PHE B 1 149 ? -52.762 83.435  39.108  1    134.6  ? 138 PHE B CA  1 -0.484 0.765  0.098  
ATOM   4093  C  C   . PHE B 1 149 ? -52.546 82.225  38.213  1    130.86 ? 138 PHE B C   1 -0.482 0.754  0.095  
ATOM   4094  O  O   . PHE B 1 149 ? -52.765 82.325  37.004  1    140.25 ? 138 PHE B O   1 -0.484 0.754  0.092  
ATOM   4095  C  CB  . PHE B 1 149 ? -51.876 84.597  38.646  1    137.35 ? 138 PHE B CB  1 -0.475 0.775  0.096  
ATOM   4096  C  CG  . PHE B 1 149 ? -52.511 85.946  38.83   1    144.13 ? 138 PHE B CG  1 -0.481 0.788  0.097  
ATOM   4097  C  CD1 . PHE B 1 149 ? -52.98  86.338  40.075  1    136.24 ? 138 PHE B CD1 1 -0.486 0.791  0.1    
ATOM   4098  C  CD2 . PHE B 1 149 ? -52.644 86.823  37.752  1    150.38 ? 138 PHE B CD2 1 -0.482 0.796  0.094  
ATOM   4099  C  CE1 . PHE B 1 149 ? -53.57  87.58   40.25   1    143.56 ? 138 PHE B CE1 1 -0.491 0.803  0.1    
ATOM   4100  C  CE2 . PHE B 1 149 ? -53.234 88.074  37.917  1    146.1  ? 138 PHE B CE2 1 -0.488 0.807  0.095  
ATOM   4101  C  CZ  . PHE B 1 149 ? -53.697 88.452  39.166  1    151.99 ? 138 PHE B CZ  1 -0.492 0.811  0.098  
ATOM   4102  N  N   . GLY B 1 150 ? -52.147 81.081  38.769  1    128.11 ? 139 GLY B N   1 -0.478 0.743  0.097  
ATOM   4103  C  CA  . GLY B 1 150 ? -51.743 79.941  37.975  1    124.29 ? 139 GLY B CA  1 -0.474 0.733  0.095  
ATOM   4104  C  C   . GLY B 1 150 ? -50.33  80.009  37.432  1    127.7  ? 139 GLY B C   1 -0.461 0.733  0.093  
ATOM   4105  O  O   . GLY B 1 150 ? -49.739 78.959  37.146  1    125.73 ? 139 GLY B O   1 -0.456 0.724  0.093  
ATOM   4106  N  N   . PHE B 1 151 ? -49.765 81.207  37.281  1    127.83 ? 140 PHE B N   1 -0.456 0.744  0.093  
ATOM   4107  C  CA  . PHE B 1 151 ? -48.403 81.373  36.796  1    127.7  ? 140 PHE B CA  1 -0.444 0.746  0.092  
ATOM   4108  C  C   . PHE B 1 151 ? -47.736 82.491  37.584  1    125.93 ? 140 PHE B C   1 -0.437 0.756  0.094  
ATOM   4109  O  O   . PHE B 1 151 ? -48.404 83.318  38.208  1    130.79 ? 140 PHE B O   1 -0.444 0.764  0.095  
ATOM   4110  C  CB  . PHE B 1 151 ? -48.373 81.655  35.281  1    129.08 ? 140 PHE B CB  1 -0.443 0.748  0.088  
ATOM   4111  C  CG  . PHE B 1 151 ? -48.595 83.099  34.91   1    130.47 ? 140 PHE B CG  1 -0.445 0.762  0.087  
ATOM   4112  C  CD1 . PHE B 1 151 ? -49.877 83.617  34.792  1    130.24 ? 140 PHE B CD1 1 -0.457 0.766  0.087  
ATOM   4113  C  CD2 . PHE B 1 151 ? -47.515 83.93   34.642  1    132.02 ? 140 PHE B CD2 1 -0.435 0.769  0.086  
ATOM   4114  C  CE1 . PHE B 1 151 ? -50.073 84.946  34.43   1    134.4  ? 140 PHE B CE1 1 -0.459 0.778  0.086  
ATOM   4115  C  CE2 . PHE B 1 151 ? -47.705 85.254  34.279  1    134.58 ? 140 PHE B CE2 1 -0.437 0.781  0.086  
ATOM   4116  C  CZ  . PHE B 1 151 ? -48.984 85.764  34.172  1    132.44 ? 140 PHE B CZ  1 -0.449 0.786  0.085  
ATOM   4117  N  N   . LYS B 1 152 ? -46.399 82.51   37.549  1    122.3  ? 141 LYS B N   1 -0.425 0.756  0.094  
ATOM   4118  C  CA  . LYS B 1 152 ? -45.631 83.403  38.419  1    119.29 ? 141 LYS B CA  1 -0.418 0.764  0.096  
ATOM   4119  C  C   . LYS B 1 152 ? -44.229 83.543  37.822  1    116.84 ? 141 LYS B C   1 -0.405 0.766  0.094  
ATOM   4120  O  O   . LYS B 1 152 ? -43.422 82.612  37.896  1    111.28 ? 141 LYS B O   1 -0.398 0.757  0.095  
ATOM   4121  C  CB  . LYS B 1 152 ? -45.607 82.863  39.843  1    122.71 ? 141 LYS B CB  1 -0.418 0.759  0.099  
ATOM   4122  C  CG  . LYS B 1 152 ? -44.588 83.486  40.816  1    126.03 ? 141 LYS B CG  1 -0.409 0.765  0.102  
ATOM   4123  C  CD  . LYS B 1 152 ? -44.686 85.005  40.893  1    124.33 ? 141 LYS B CD  1 -0.41  0.779  0.102  
ATOM   4124  C  CE  . LYS B 1 152 ? -44.012 85.519  42.149  1    120.5  ? 141 LYS B CE  1 -0.403 0.784  0.105  
ATOM   4125  N  NZ  . LYS B 1 152 ? -44.933 85.377  43.321  1    126.51 ? 141 LYS B NZ  1 -0.412 0.782  0.108  
ATOM   4126  N  N   . GLN B 1 153 ? -43.962 84.701  37.232  1    122.13 ? 142 GLN B N   1 -0.403 0.776  0.093  
ATOM   4127  C  CA  . GLN B 1 153 ? -42.728 84.908  36.485  1    128.3  ? 142 GLN B CA  1 -0.392 0.778  0.091  
ATOM   4128  C  C   . GLN B 1 153 ? -41.604 85.325  37.423  1    121.93 ? 142 GLN B C   1 -0.381 0.782  0.093  
ATOM   4129  O  O   . GLN B 1 153 ? -41.822 86.095  38.355  1    120.45 ? 142 GLN B O   1 -0.383 0.789  0.096  
ATOM   4130  C  CB  . GLN B 1 153 ? -42.954 85.972  35.395  1    130.64 ? 142 GLN B CB  1 -0.394 0.788  0.088  
ATOM   4131  C  CG  . GLN B 1 153 ? -41.729 86.357  34.541  1    131.6  ? 142 GLN B CG  1 -0.382 0.791  0.086  
ATOM   4132  C  CD  . GLN B 1 153 ? -40.929 87.557  35.094  1    137.73 ? 142 GLN B CD  1 -0.375 0.802  0.088  
ATOM   4133  O  OE1 . GLN B 1 153 ? -40.862 87.786  36.318  1    135.85 ? 142 GLN B OE1 1 -0.374 0.804  0.091  
ATOM   4134  N  NE2 . GLN B 1 153 ? -40.331 88.334  34.182  1    127.91 ? 142 GLN B NE2 1 -0.37  0.81   0.085  
ATOM   4135  N  N   . LEU B 1 154 ? -40.395 84.825  37.162  1    122.25 ? 143 LEU B N   1 -0.37  0.777  0.093  
ATOM   4136  C  CA  . LEU B 1 154 ? -39.211 85.275  37.893  1    123.96 ? 143 LEU B CA  1 -0.359 0.781  0.095  
ATOM   4137  C  C   . LEU B 1 154 ? -38.431 86.298  37.072  1    129.54 ? 143 LEU B C   1 -0.352 0.791  0.093  
ATOM   4138  O  O   . LEU B 1 154 ? -38.305 87.463  37.471  1    126.22 ? 143 LEU B O   1 -0.351 0.802  0.094  
ATOM   4139  C  CB  . LEU B 1 154 ? -38.28  84.11   38.242  1    123.39 ? 143 LEU B CB  1 -0.351 0.771  0.095  
ATOM   4140  C  CG  . LEU B 1 154 ? -38.807 82.833  38.898  1    118.37 ? 143 LEU B CG  1 -0.356 0.759  0.097  
ATOM   4141  C  CD1 . LEU B 1 154 ? -37.676 82.088  39.592  1    107.93 ? 143 LEU B CD1 1 -0.345 0.752  0.099  
ATOM   4142  C  CD2 . LEU B 1 154 ? -39.917 83.135  39.847  1    114.28 ? 143 LEU B CD2 1 -0.366 0.762  0.099  
ATOM   4143  N  N   . ASN B 1 155 ? -37.879 85.836  35.946  1    131.13 ? 144 ASN B N   1 -0.347 0.787  0.09   
ATOM   4144  C  CA  . ASN B 1 155 ? -37.191 86.61   34.916  1    128.5  ? 144 ASN B CA  1 -0.341 0.794  0.087  
ATOM   4145  C  C   . ASN B 1 155 ? -37.966 86.481  33.615  1    130.05 ? 144 ASN B C   1 -0.348 0.793  0.084  
ATOM   4146  O  O   . ASN B 1 155 ? -38.953 85.746  33.525  1    130.72 ? 144 ASN B O   1 -0.357 0.786  0.084  
ATOM   4147  C  CB  . ASN B 1 155 ? -35.755 86.114  34.715  1    130.16 ? 144 ASN B CB  1 -0.328 0.789  0.087  
ATOM   4148  C  CG  . ASN B 1 155 ? -34.711 87.074  35.273  1    138.71 ? 144 ASN B CG  1 -0.318 0.798  0.088  
ATOM   4149  O  OD1 . ASN B 1 155 ? -34.882 88.3    35.214  1    145.08 ? 144 ASN B OD1 1 -0.32  0.809  0.088  
ATOM   4150  N  ND2 . ASN B 1 155 ? -33.609 86.519  35.797  1    119.96 ? 144 ASN B ND2 1 -0.308 0.793  0.089  
ATOM   4151  N  N   . ALA B 1 156 ? -37.495 87.183  32.585  1    132.57 ? 145 ALA B N   1 -0.344 0.799  0.081  
ATOM   4152  C  CA  . ALA B 1 156 ? -38.113 87.045  31.267  1    132    ? 145 ALA B CA  1 -0.349 0.798  0.078  
ATOM   4153  C  C   . ALA B 1 156 ? -38.114 85.598  30.796  1    131.23 ? 145 ALA B C   1 -0.349 0.784  0.077  
ATOM   4154  O  O   . ALA B 1 156 ? -39     85.182  30.039  1    126.16 ? 145 ALA B O   1 -0.357 0.781  0.075  
ATOM   4155  C  CB  . ALA B 1 156 ? -37.379 87.913  30.248  1    131.28 ? 145 ALA B CB  1 -0.343 0.806  0.076  
ATOM   4156  N  N   . ASP B 1 157 ? -37.135 84.815  31.246  1    131.74 ? 146 ASP B N   1 -0.34  0.777  0.078  
ATOM   4157  C  CA  . ASP B 1 157 ? -36.904 83.465  30.758  1    127.98 ? 146 ASP B CA  1 -0.338 0.765  0.077  
ATOM   4158  C  C   . ASP B 1 157 ? -37.185 82.425  31.828  1    122.89 ? 146 ASP B C   1 -0.341 0.755  0.079  
ATOM   4159  O  O   . ASP B 1 157 ? -36.597 81.342  31.809  1    121.5  ? 146 ASP B O   1 -0.335 0.745  0.079  
ATOM   4160  C  CB  . ASP B 1 157 ? -35.463 83.328  30.261  1    129.06 ? 146 ASP B CB  1 -0.325 0.764  0.076  
ATOM   4161  C  CG  . ASP B 1 157 ? -35.031 84.493  29.389  1    132.97 ? 146 ASP B CG  1 -0.321 0.774  0.073  
ATOM   4162  O  OD1 . ASP B 1 157 ? -35.776 84.839  28.439  1    133.85 ? 146 ASP B OD1 1 -0.328 0.777  0.071  
ATOM   4163  O  OD2 . ASP B 1 157 ? -33.95  85.068  29.665  1    131.61 ? 146 ASP B OD2 1 -0.311 0.78   0.074  
ATOM   4164  N  N   . LEU B 1 158 ? -38.076 82.748  32.766  1    122.61 ? 147 LEU B N   1 -0.349 0.758  0.082  
ATOM   4165  C  CA  . LEU B 1 158 ? -38.318 81.883  33.927  1    120.09 ? 147 LEU B CA  1 -0.351 0.75   0.085  
ATOM   4166  C  C   . LEU B 1 158 ? -39.749 82.101  34.394  1    122.54 ? 147 LEU B C   1 -0.364 0.752  0.086  
ATOM   4167  O  O   . LEU B 1 158 ? -40.093 83.208  34.819  1    125.01 ? 147 LEU B O   1 -0.367 0.763  0.087  
ATOM   4168  C  CB  . LEU B 1 158 ? -37.344 82.195  35.05   1    120.79 ? 147 LEU B CB  1 -0.342 0.753  0.088  
ATOM   4169  C  CG  . LEU B 1 158 ? -35.985 81.506  35.099  1    118.08 ? 147 LEU B CG  1 -0.33  0.747  0.088  
ATOM   4170  C  CD1 . LEU B 1 158 ? -35.273 81.895  36.385  1    111.09 ? 147 LEU B CD1 1 -0.323 0.75   0.091  
ATOM   4171  C  CD2 . LEU B 1 158 ? -36.13  79.995  34.979  1    109.25 ? 147 LEU B CD2 1 -0.331 0.733  0.087  
ATOM   4172  N  N   . VAL B 1 159 ? -40.567 81.058  34.33   1    120.89 ? 148 VAL B N   1 -0.372 0.743  0.086  
ATOM   4173  C  CA  . VAL B 1 159 ? -41.932 81.102  34.835  1    116.59 ? 148 VAL B CA  1 -0.384 0.743  0.087  
ATOM   4174  C  C   . VAL B 1 159 ? -42.19  79.817  35.615  1    114.5  ? 148 VAL B C   1 -0.387 0.731  0.089  
ATOM   4175  O  O   . VAL B 1 159 ? -41.582 78.777  35.336  1    118.15 ? 148 VAL B O   1 -0.381 0.722  0.088  
ATOM   4176  C  CB  . VAL B 1 159 ? -42.957 81.288  33.688  1    109.39 ? 148 VAL B CB  1 -0.394 0.745  0.084  
ATOM   4177  C  CG1 . VAL B 1 159 ? -44.359 81.483  34.233  1    114.69 ? 148 VAL B CG1 1 -0.407 0.747  0.085  
ATOM   4178  C  CG2 . VAL B 1 159 ? -42.58  82.48   32.838  1    110.33 ? 148 VAL B CG2 1 -0.39  0.756  0.082  
ATOM   4179  N  N   . VAL B 1 160 ? -43.074 79.887  36.613  1    108.79 ? 149 VAL B N   1 -0.395 0.732  0.091  
ATOM   4180  C  CA  . VAL B 1 160 ? -43.47  78.69   37.338  1    105.3  ? 149 VAL B CA  1 -0.398 0.721  0.093  
ATOM   4181  C  C   . VAL B 1 160 ? -44.987 78.61   37.387  1    104.97 ? 149 VAL B C   1 -0.412 0.72   0.093  
ATOM   4182  O  O   . VAL B 1 160 ? -45.702 79.584  37.149  1    109.31 ? 149 VAL B O   1 -0.419 0.729  0.093  
ATOM   4183  C  CB  . VAL B 1 160 ? -42.878 78.622  38.762  1    105.38 ? 149 VAL B CB  1 -0.393 0.721  0.097  
ATOM   4184  C  CG1 . VAL B 1 160 ? -41.452 78.079  38.73   1    106.6  ? 149 VAL B CG1 1 -0.38  0.716  0.097  
ATOM   4185  C  CG2 . VAL B 1 160 ? -42.89  79.977  39.404  1    107.73 ? 149 VAL B CG2 1 -0.393 0.733  0.098  
ATOM   4186  N  N   . THR B 1 161 ? -45.465 77.41   37.667  1    101.39 ? 150 THR B N   1 -0.417 0.709  0.094  
ATOM   4187  C  CA  . THR B 1 161 ? -46.868 77.09   37.873  1    109.54 ? 150 THR B CA  1 -0.43  0.706  0.095  
ATOM   4188  C  C   . THR B 1 161 ? -46.975 76.201  39.099  1    108.23 ? 150 THR B C   1 -0.43  0.698  0.098  
ATOM   4189  O  O   . THR B 1 161 ? -46.007 75.526  39.467  1    107.3  ? 150 THR B O   1 -0.422 0.692  0.099  
ATOM   4190  C  CB  . THR B 1 161 ? -47.466 76.38   36.642  1    109.62 ? 150 THR B CB  1 -0.435 0.7    0.091  
ATOM   4191  O  OG1 . THR B 1 161 ? -48.13  75.171  37.048  1    107.97 ? 150 THR B OG1 1 -0.441 0.689  0.093  
ATOM   4192  C  CG2 . THR B 1 161 ? -46.377 76.042  35.627  1    112.97 ? 150 THR B CG2 1 -0.425 0.697  0.089  
ATOM   4193  N  N   . PRO B 1 162 ? -48.135 76.18   39.756  1    104.15 ? 151 PRO B N   1 -0.441 0.698  0.099  
ATOM   4194  C  CA  . PRO B 1 162 ? -48.293 75.362  40.984  1    107.62 ? 151 PRO B CA  1 -0.443 0.691  0.102  
ATOM   4195  C  C   . PRO B 1 162 ? -47.687 73.972  40.913  1    106.82 ? 151 PRO B C   1 -0.437 0.678  0.102  
ATOM   4196  O  O   . PRO B 1 162 ? -47.075 73.537  41.891  1    117.7  ? 151 PRO B O   1 -0.431 0.674  0.105  
ATOM   4197  C  CB  . PRO B 1 162 ? -49.818 75.31   41.153  1    108.88 ? 151 PRO B CB  1 -0.457 0.69   0.103  
ATOM   4198  C  CG  . PRO B 1 162 ? -50.27  76.624  40.609  1    114.8  ? 151 PRO B CG  1 -0.461 0.702  0.101  
ATOM   4199  C  CD  . PRO B 1 162 ? -49.351 76.967  39.459  1    107.61 ? 151 PRO B CD  1 -0.452 0.705  0.099  
ATOM   4200  N  N   . LYS B 1 163 ? -47.79  73.277  39.793  1    107.01 ? 152 LYS B N   1 -0.438 0.672  0.099  
ATOM   4201  C  CA  . LYS B 1 163 ? -47.288 71.915  39.689  1    108.65 ? 152 LYS B CA  1 -0.433 0.659  0.099  
ATOM   4202  C  C   . LYS B 1 163 ? -45.903 71.806  39.057  1    103.42 ? 152 LYS B C   1 -0.421 0.658  0.098  
ATOM   4203  O  O   . LYS B 1 163 ? -45.439 70.678  38.836  1    99.66  ? 152 LYS B O   1 -0.416 0.648  0.097  
ATOM   4204  C  CB  . LYS B 1 163 ? -48.281 71.056  38.909  1    114.08 ? 152 LYS B CB  1 -0.442 0.651  0.097  
ATOM   4205  C  CG  . LYS B 1 163 ? -49.566 70.761  39.66   1    113.88 ? 152 LYS B CG  1 -0.454 0.648  0.099  
ATOM   4206  C  CD  . LYS B 1 163 ? -49.355 69.78   40.809  1    121.43 ? 152 LYS B CD  1 -0.452 0.639  0.102  
ATOM   4207  C  CE  . LYS B 1 163 ? -50.689 69.232  41.345  1    125.55 ? 152 LYS B CE  1 -0.465 0.634  0.103  
ATOM   4208  N  NZ  . LYS B 1 163 ? -50.629 67.753  41.493  1    119.57 ? 152 LYS B NZ  1 -0.464 0.621  0.104  
ATOM   4209  N  N   . THR B 1 164 ? -45.225 72.933  38.785  1    94.18  ? 153 THR B N   1 -0.414 0.668  0.097  
ATOM   4210  C  CA  . THR B 1 164 ? -43.876 72.886  38.217  1    89.99  ? 153 THR B CA  1 -0.402 0.668  0.095  
ATOM   4211  C  C   . THR B 1 164 ? -42.977 71.947  38.989  1    102.07 ? 153 THR B C   1 -0.394 0.659  0.097  
ATOM   4212  O  O   . THR B 1 164 ? -42.262 71.126  38.399  1    103.09 ? 153 THR B O   1 -0.387 0.652  0.096  
ATOM   4213  C  CB  . THR B 1 164 ? -43.21  74.258  38.225  1    93.98  ? 153 THR B CB  1 -0.396 0.681  0.095  
ATOM   4214  O  OG1 . THR B 1 164 ? -43.977 75.196  37.464  1    102.29 ? 153 THR B OG1 1 -0.403 0.689  0.094  
ATOM   4215  C  CG2 . THR B 1 164 ? -41.787 74.137  37.657  1    87.39  ? 153 THR B CG2 1 -0.383 0.679  0.094  
ATOM   4216  N  N   . PHE B 1 165 ? -42.97  72.103  40.321  1    103.94 ? 154 PHE B N   1 -0.394 0.661  0.101  
ATOM   4217  C  CA  . PHE B 1 165 ? -42.095 71.309  41.173  1    98.53  ? 154 PHE B CA  1 -0.386 0.653  0.103  
ATOM   4218  C  C   . PHE B 1 165 ? -42.457 69.829  41.095  1    102.1  ? 154 PHE B C   1 -0.389 0.64   0.103  
ATOM   4219  O  O   . PHE B 1 165 ? -41.57  68.977  40.956  1    100.96 ? 154 PHE B O   1 -0.381 0.632  0.102  
ATOM   4220  C  CB  . PHE B 1 165 ? -42.147 71.819  42.626  1    102.69 ? 154 PHE B CB  1 -0.386 0.658  0.106  
ATOM   4221  C  CG  . PHE B 1 165 ? -41.101 71.19   43.529  1    100.47 ? 154 PHE B CG  1 -0.377 0.652  0.109  
ATOM   4222  C  CD1 . PHE B 1 165 ? -39.814 71.716  43.601  1    100.11 ? 154 PHE B CD1 1 -0.365 0.657  0.109  
ATOM   4223  C  CD2 . PHE B 1 165 ? -41.395 70.06   44.277  1    98.05  ? 154 PHE B CD2 1 -0.379 0.642  0.111  
ATOM   4224  C  CE1 . PHE B 1 165 ? -38.84  71.131  44.411  1    91.48  ? 154 PHE B CE1 1 -0.356 0.652  0.111  
ATOM   4225  C  CE2 . PHE B 1 165 ? -40.423 69.472  45.081  1    97.18  ? 154 PHE B CE2 1 -0.37  0.637  0.113  
ATOM   4226  C  CZ  . PHE B 1 165 ? -39.146 70.01   45.141  1    92.66  ? 154 PHE B CZ  1 -0.359 0.642  0.113  
ATOM   4227  N  N   . GLU B 1 166 ? -43.754 69.499  41.19   1    104.13 ? 155 GLU B N   1 -0.401 0.637  0.103  
ATOM   4228  C  CA  . GLU B 1 166 ? -44.168 68.099  41.067  1    108.62 ? 155 GLU B CA  1 -0.405 0.624  0.103  
ATOM   4229  C  C   . GLU B 1 166 ? -43.847 67.563  39.685  1    105.58 ? 155 GLU B C   1 -0.402 0.619  0.099  
ATOM   4230  O  O   . GLU B 1 166 ? -43.315 66.452  39.548  1    104.02 ? 155 GLU B O   1 -0.397 0.609  0.099  
ATOM   4231  C  CB  . GLU B 1 166 ? -45.663 67.942  41.357  1    115.14 ? 155 GLU B CB  1 -0.418 0.623  0.103  
ATOM   4232  C  CG  . GLU B 1 166 ? -46.297 66.721  40.704  1    116.28 ? 155 GLU B CG  1 -0.424 0.611  0.102  
ATOM   4233  C  CD  . GLU B 1 166 ? -47.521 66.233  41.475  1    120.88 ? 155 GLU B CD  1 -0.435 0.607  0.104  
ATOM   4234  O  OE1 . GLU B 1 166 ? -47.755 64.993  41.441  1    125.76 ? 155 GLU B OE1 1 -0.438 0.596  0.103  
ATOM   4235  O  OE2 . GLU B 1 166 ? -48.231 67.049  42.098  1    120.57 ? 155 GLU B OE2 1 -0.442 0.614  0.105  
ATOM   4236  N  N   . ILE B 1 167 ? -44.141 68.359  38.655  1    106.18 ? 156 ILE B N   1 -0.405 0.626  0.097  
ATOM   4237  C  CA  . ILE B 1 167 ? -43.834 67.969  37.281  1    102.32 ? 156 ILE B CA  1 -0.402 0.623  0.093  
ATOM   4238  C  C   . ILE B 1 167 ? -42.336 67.73   37.127  1    99.72  ? 156 ILE B C   1 -0.388 0.621  0.093  
ATOM   4239  O  O   . ILE B 1 167 ? -41.904 66.665  36.667  1    100.54 ? 156 ILE B O   1 -0.384 0.611  0.092  
ATOM   4240  C  CB  . ILE B 1 167 ? -44.349 69.037  36.297  1    98.61  ? 156 ILE B CB  1 -0.406 0.633  0.091  
ATOM   4241  C  CG1 . ILE B 1 167 ? -45.808 68.787  35.869  1    103.1  ? 156 ILE B CG1 1 -0.42  0.63   0.09   
ATOM   4242  C  CG2 . ILE B 1 167 ? -43.504 69.049  35.048  1    102.91 ? 156 ILE B CG2 1 -0.399 0.633  0.088  
ATOM   4243  C  CD1 . ILE B 1 167 ? -46.837 68.432  36.968  1    111.13 ? 156 ILE B CD1 1 -0.429 0.627  0.092  
ATOM   4244  N  N   . LEU B 1 168 ? -41.519 68.705  37.541  1    94.93  ? 157 LEU B N   1 -0.38  0.63   0.094  
ATOM   4245  C  CA  . LEU B 1 168 ? -40.07  68.56   37.428  1    96.38  ? 157 LEU B CA  1 -0.367 0.628  0.093  
ATOM   4246  C  C   . LEU B 1 168 ? -39.559 67.35   38.21   1    104.48 ? 157 LEU B C   1 -0.363 0.617  0.095  
ATOM   4247  O  O   . LEU B 1 168 ? -38.649 66.646  37.754  1    101.95 ? 157 LEU B O   1 -0.354 0.611  0.094  
ATOM   4248  C  CB  . LEU B 1 168 ? -39.378 69.839  37.901  1    90.41  ? 157 LEU B CB  1 -0.361 0.64   0.095  
ATOM   4249  C  CG  . LEU B 1 168 ? -39.073 70.796  36.765  1    95.11  ? 157 LEU B CG  1 -0.358 0.649  0.092  
ATOM   4250  C  CD1 . LEU B 1 168 ? -38.33  72.022  37.224  1    91.54  ? 157 LEU B CD1 1 -0.351 0.66   0.093  
ATOM   4251  C  CD2 . LEU B 1 168 ? -38.269 70.042  35.701  1    107.59 ? 157 LEU B CD2 1 -0.351 0.642  0.089  
ATOM   4252  N  N   . ILE B 1 169 ? -40.133 67.091  39.392  1    105.03 ? 158 ILE B N   1 -0.368 0.615  0.098  
ATOM   4253  C  CA  . ILE B 1 169 ? -39.659 65.976  40.206  1    104.54 ? 158 ILE B CA  1 -0.363 0.605  0.1    
ATOM   4254  C  C   . ILE B 1 169 ? -40.08  64.653  39.58   1    104.33 ? 158 ILE B C   1 -0.367 0.592  0.099  
ATOM   4255  O  O   . ILE B 1 169 ? -39.273 63.719  39.472  1    106.06 ? 158 ILE B O   1 -0.36  0.584  0.099  
ATOM   4256  C  CB  . ILE B 1 169 ? -40.142 66.101  41.668  1    107.33 ? 158 ILE B CB  1 -0.368 0.606  0.104  
ATOM   4257  C  CG1 . ILE B 1 169 ? -39.277 67.094  42.443  1    94.02  ? 158 ILE B CG1 1 -0.36  0.615  0.106  
ATOM   4258  C  CG2 . ILE B 1 169 ? -40.026 64.746  42.395  1    102.22 ? 158 ILE B CG2 1 -0.367 0.593  0.106  
ATOM   4259  C  CD1 . ILE B 1 169 ? -38.006 66.435  43.015  1    89.39  ? 158 ILE B CD1 1 -0.348 0.609  0.107  
ATOM   4260  N  N   . ARG B 1 170 ? -41.343 64.556  39.139  1    103.95 ? 159 ARG B N   1 -0.379 0.592  0.098  
ATOM   4261  C  CA  . ARG B 1 170 ? -41.793 63.322  38.494  1    106.48 ? 159 ARG B CA  1 -0.383 0.58   0.096  
ATOM   4262  C  C   . ARG B 1 170 ? -40.963 63.007  37.255  1    109.09 ? 159 ARG B C   1 -0.375 0.577  0.093  
ATOM   4263  O  O   . ARG B 1 170 ? -40.763 61.831  36.927  1    112.46 ? 159 ARG B O   1 -0.374 0.567  0.092  
ATOM   4264  C  CB  . ARG B 1 170 ? -43.275 63.41   38.132  1    106.51 ? 159 ARG B CB  1 -0.397 0.581  0.095  
ATOM   4265  C  CG  . ARG B 1 170 ? -44.212 63.363  39.318  1    112.27 ? 159 ARG B CG  1 -0.405 0.581  0.098  
ATOM   4266  C  CD  . ARG B 1 170 ? -45.668 63.29   38.871  1    116.83 ? 159 ARG B CD  1 -0.419 0.58   0.097  
ATOM   4267  N  NE  . ARG B 1 170 ? -46.576 63.112  40.002  1    119.38 ? 159 ARG B NE  1 -0.427 0.578  0.1    
ATOM   4268  C  CZ  . ARG B 1 170 ? -46.892 61.939  40.537  1    113.51 ? 159 ARG B CZ  1 -0.43  0.568  0.101  
ATOM   4269  N  NH1 . ARG B 1 170 ? -46.36  60.809  40.095  1    110.4  ? 159 ARG B NH1 1 -0.425 0.557  0.1    
ATOM   4270  N  NH2 . ARG B 1 170 ? -47.767 61.897  41.539  1    117    ? 159 ARG B NH2 1 -0.438 0.567  0.104  
ATOM   4271  N  N   . ASP B 1 171 ? -40.47  64.038  36.56   1    107.91 ? 160 ASP B N   1 -0.371 0.587  0.091  
ATOM   4272  C  CA  . ASP B 1 171 ? -39.539 63.817  35.457  1    109.43 ? 160 ASP B CA  1 -0.362 0.585  0.089  
ATOM   4273  C  C   . ASP B 1 171 ? -38.266 63.125  35.948  1    110.49 ? 160 ASP B C   1 -0.351 0.578  0.09   
ATOM   4274  O  O   . ASP B 1 171 ? -37.923 62.032  35.478  1    110.19 ? 160 ASP B O   1 -0.348 0.568  0.089  
ATOM   4275  C  CB  . ASP B 1 171 ? -39.212 65.151  34.769  1    109.43 ? 160 ASP B CB  1 -0.359 0.597  0.087  
ATOM   4276  C  CG  . ASP B 1 171 ? -38.257 64.998  33.575  1    114.43 ? 160 ASP B CG  1 -0.351 0.596  0.084  
ATOM   4277  O  OD1 . ASP B 1 171 ? -38.018 63.857  33.117  1    118.5  ? 160 ASP B OD1 1 -0.348 0.585  0.083  
ATOM   4278  O  OD2 . ASP B 1 171 ? -37.737 66.032  33.089  1    114.47 ? 160 ASP B OD2 1 -0.346 0.605  0.083  
ATOM   4279  N  N   . CYS B 1 172 ? -37.557 63.745  36.909  1    110.54 ? 161 CYS B N   1 -0.344 0.584  0.092  
ATOM   4280  C  CA  . CYS B 1 172 ? -36.305 63.174  37.418  1    109.66 ? 161 CYS B CA  1 -0.333 0.579  0.093  
ATOM   4281  C  C   . CYS B 1 172 ? -36.517 61.776  37.987  1    102.91 ? 161 CYS B C   1 -0.335 0.566  0.095  
ATOM   4282  O  O   . CYS B 1 172 ? -35.631 60.916  37.89   1    94.72  ? 161 CYS B O   1 -0.327 0.558  0.095  
ATOM   4283  C  CB  . CYS B 1 172 ? -35.692 64.095  38.486  1    106.15 ? 161 CYS B CB  1 -0.327 0.587  0.096  
ATOM   4284  S  SG  . CYS B 1 172 ? -35.288 65.814  37.927  1    110.33 ? 161 CYS B SG  1 -0.323 0.603  0.095  
ATOM   4285  N  N   . ALA B 1 173 ? -37.693 61.522  38.555  1    100.52 ? 162 ALA B N   1 -0.345 0.564  0.096  
ATOM   4286  C  CA  . ALA B 1 173 ? -37.971 60.205  39.106  1    105.64 ? 162 ALA B CA  1 -0.348 0.552  0.098  
ATOM   4287  C  C   . ALA B 1 173 ? -38.02  59.145  38.012  1    106.23 ? 162 ALA B C   1 -0.348 0.542  0.095  
ATOM   4288  O  O   . ALA B 1 173 ? -37.355 58.106  38.117  1    101.31 ? 162 ALA B O   1 -0.342 0.532  0.095  
ATOM   4289  C  CB  . ALA B 1 173 ? -39.286 60.239  39.87   1    106.81 ? 162 ALA B CB  1 -0.36  0.552  0.1    
ATOM   4290  N  N   . THR B 1 174 ? -38.821 59.397  36.97   1    108.25 ? 163 THR B N   1 -0.356 0.544  0.092  
ATOM   4291  C  CA  . THR B 1 174 ? -39.057 58.43   35.897  1    108.18 ? 163 THR B CA  1 -0.358 0.535  0.09   
ATOM   4292  C  C   . THR B 1 174 ? -37.753 57.953  35.254  1    102.87 ? 163 THR B C   1 -0.346 0.531  0.088  
ATOM   4293  O  O   . THR B 1 174 ? -37.559 56.75   35.033  1    100.75 ? 163 THR B O   1 -0.344 0.52   0.087  
ATOM   4294  C  CB  . THR B 1 174 ? -39.984 59.056  34.854  1    114.35 ? 163 THR B CB  1 -0.366 0.541  0.087  
ATOM   4295  O  OG1 . THR B 1 174 ? -41.236 59.401  35.475  1    112.28 ? 163 THR B OG1 1 -0.378 0.544  0.089  
ATOM   4296  C  CG2 . THR B 1 174 ? -40.21  58.1    33.643  1    110.18 ? 163 THR B CG2 1 -0.368 0.532  0.084  
ATOM   4297  N  N   . THR B 1 175 ? -36.847 58.883  34.942  1    95.53  ? 164 THR B N   1 -0.338 0.54   0.087  
ATOM   4298  C  CA  . THR B 1 175 ? -35.521 58.484  34.487  1    97.14  ? 164 THR B CA  1 -0.326 0.536  0.086  
ATOM   4299  C  C   . THR B 1 175 ? -34.809 57.643  35.539  1    107.68 ? 164 THR B C   1 -0.319 0.528  0.089  
ATOM   4300  O  O   . THR B 1 175 ? -34.129 56.662  35.206  1    111.59 ? 164 THR B O   1 -0.313 0.519  0.088  
ATOM   4301  C  CB  . THR B 1 175 ? -34.683 59.719  34.134  1    100.84 ? 164 THR B CB  1 -0.318 0.547  0.085  
ATOM   4302  O  OG1 . THR B 1 175 ? -35.34  60.487  33.11   1    105.45 ? 164 THR B OG1 1 -0.324 0.554  0.083  
ATOM   4303  C  CG2 . THR B 1 175 ? -33.313 59.302  33.632  1    100.03 ? 164 THR B CG2 1 -0.305 0.543  0.084  
ATOM   4304  N  N   . LEU B 1 176 ? -34.979 57.992  36.823  1    109.98 ? 165 LEU B N   1 -0.321 0.531  0.092  
ATOM   4305  C  CA  . LEU B 1 176 ? -34.215 57.378  37.903  1    102.05 ? 165 LEU B CA  1 -0.314 0.526  0.095  
ATOM   4306  C  C   . LEU B 1 176 ? -34.799 56.053  38.389  1    107.11 ? 165 LEU B C   1 -0.319 0.514  0.096  
ATOM   4307  O  O   . LEU B 1 176 ? -34.057 55.226  38.934  1    107.49 ? 165 LEU B O   1 -0.312 0.506  0.097  
ATOM   4308  C  CB  . LEU B 1 176 ? -34.111 58.36   39.066  1    107.69 ? 165 LEU B CB  1 -0.313 0.535  0.098  
ATOM   4309  C  CG  . LEU B 1 176 ? -33.05  59.463  39.045  1    98.84  ? 165 LEU B CG  1 -0.303 0.545  0.097  
ATOM   4310  C  CD1 . LEU B 1 176 ? -33.274 60.391  40.21   1    104.19 ? 165 LEU B CD1 1 -0.305 0.553  0.1    
ATOM   4311  C  CD2 . LEU B 1 176 ? -31.679 58.865  39.148  1    96.6   ? 165 LEU B CD2 1 -0.29  0.539  0.098  
ATOM   4312  N  N   . PHE B 1 177 ? -36.102 55.832  38.225  1    107.8  ? 166 PHE B N   1 -0.331 0.512  0.095  
ATOM   4313  C  CA  . PHE B 1 177 ? -36.731 54.553  38.562  1    113.47 ? 166 PHE B CA  1 -0.337 0.5    0.096  
ATOM   4314  C  C   . PHE B 1 177 ? -36.939 53.673  37.319  1    122.1  ? 166 PHE B C   1 -0.339 0.492  0.093  
ATOM   4315  O  O   . PHE B 1 177 ? -37.95  52.968  37.191  1    123.26 ? 166 PHE B O   1 -0.348 0.485  0.093  
ATOM   4316  C  CB  . PHE B 1 177 ? -38.057 54.79   39.286  1    114.77 ? 166 PHE B CB  1 -0.349 0.502  0.098  
ATOM   4317  C  CG  . PHE B 1 177 ? -37.961 55.731  40.462  1    114.57 ? 166 PHE B CG  1 -0.348 0.511  0.101  
ATOM   4318  C  CD1 . PHE B 1 177 ? -36.78  55.873  41.174  1    112.77 ? 166 PHE B CD1 1 -0.337 0.512  0.103  
ATOM   4319  C  CD2 . PHE B 1 177 ? -39.063 56.472  40.854  1    114.41 ? 166 PHE B CD2 1 -0.358 0.518  0.102  
ATOM   4320  C  CE1 . PHE B 1 177 ? -36.698 56.738  42.243  1    110.89 ? 166 PHE B CE1 1 -0.336 0.52   0.105  
ATOM   4321  C  CE2 . PHE B 1 177 ? -38.99  57.336  41.927  1    114.98 ? 166 PHE B CE2 1 -0.357 0.525  0.105  
ATOM   4322  C  CZ  . PHE B 1 177 ? -37.807 57.471  42.621  1    113.67 ? 166 PHE B CZ  1 -0.346 0.527  0.106  
ATOM   4323  N  N   A ASN B 1 178 ? -35.992 53.706  36.382  0.57 119.14 ? 167 ASN B N   1 -0.33  0.492  0.091  
ATOM   4324  N  N   B ASN B 1 178 ? -35.989 53.687  36.378  0.43 119.09 ? 167 ASN B N   1 -0.33  0.492  0.091  
ATOM   4325  C  CA  A ASN B 1 178 ? -36.054 52.854  35.225  0.57 121.61 ? 167 ASN B CA  1 -0.33  0.484  0.088  
ATOM   4326  C  CA  B ASN B 1 178 ? -36.089 52.851  35.184  0.43 121.61 ? 167 ASN B CA  1 -0.331 0.484  0.088  
ATOM   4327  C  C   A ASN B 1 178 ? -34.635 52.436  34.865  0.57 125.57 ? 167 ASN B C   1 -0.317 0.481  0.087  
ATOM   4328  C  C   B ASN B 1 178 ? -34.703 52.444  34.692  0.43 125.59 ? 167 ASN B C   1 -0.318 0.481  0.087  
ATOM   4329  O  O   A ASN B 1 178 ? -33.755 53.314  34.742  0.57 123.23 ? 167 ASN B O   1 -0.309 0.489  0.087  
ATOM   4330  O  O   B ASN B 1 178 ? -33.912 53.303  34.279  0.43 123.58 ? 167 ASN B O   1 -0.311 0.488  0.086  
ATOM   4331  C  CB  A ASN B 1 178 ? -36.729 53.546  34.038  0.57 121.03 ? 167 ASN B CB  1 -0.337 0.491  0.085  
ATOM   4332  C  CB  B ASN B 1 178 ? -36.855 53.585  34.079  0.43 121.34 ? 167 ASN B CB  1 -0.338 0.491  0.085  
ATOM   4333  C  CG  A ASN B 1 178 ? -36.06  53.225  32.713  0.57 121.05 ? 167 ASN B CG  1 -0.33  0.488  0.082  
ATOM   4334  C  CG  B ASN B 1 178 ? -38.365 53.501  34.254  0.43 120.75 ? 167 ASN B CG  1 -0.352 0.49   0.086  
ATOM   4335  O  OD1 A ASN B 1 178 ? -35.052 53.839  32.365  0.57 119.31 ? 167 ASN B OD1 1 -0.321 0.493  0.081  
ATOM   4336  O  OD1 B ASN B 1 178 ? -38.948 54.21   35.078  0.43 116.49 ? 167 ASN B OD1 1 -0.357 0.497  0.088  
ATOM   4337  N  ND2 A ASN B 1 178 ? -36.619 52.27   31.965  0.57 119.03 ? 167 ASN B ND2 1 -0.336 0.479  0.08   
ATOM   4338  N  ND2 B ASN B 1 178 ? -39.007 52.637  33.467  0.43 119.54 ? 167 ASN B ND2 1 -0.357 0.482  0.084  
ATOM   4339  N  N   . PRO B 1 179 ? -34.372 51.135  34.705  1    132.46 ? 168 PRO B N   1 -0.315 0.469  0.087  
ATOM   4340  C  CA  . PRO B 1 179 ? -33.04  50.663  34.249  1    132.02 ? 168 PRO B CA  1 -0.303 0.464  0.086  
ATOM   4341  C  C   . PRO B 1 179 ? -32.975 50.493  32.734  1    134.05 ? 168 PRO B C   1 -0.302 0.463  0.082  
ATOM   4342  O  O   . PRO B 1 179 ? -32.947 49.365  32.206  1    137.11 ? 168 PRO B O   1 -0.302 0.452  0.08   
ATOM   4343  C  CB  . PRO B 1 179 ? -32.906 49.327  34.98   1    134.9  ? 168 PRO B CB  1 -0.302 0.452  0.087  
ATOM   4344  C  CG  . PRO B 1 179 ? -34.333 48.784  34.944  1    139.53 ? 168 PRO B CG  1 -0.315 0.447  0.087  
ATOM   4345  C  CD  . PRO B 1 179 ? -35.254 50.006  35.064  1    130.54 ? 168 PRO B CD  1 -0.323 0.458  0.088  
ATOM   4346  N  N   . ALA B 1 180 ? -32.959 51.618  32.01   1    128.47 ? 169 ALA B N   1 -0.302 0.473  0.08   
ATOM   4347  C  CA  . ALA B 1 180 ? -32.814 51.619  30.555  1    124.93 ? 169 ALA B CA  1 -0.301 0.473  0.076  
ATOM   4348  C  C   . ALA B 1 180 ? -31.415 52.096  30.19   1    120.03 ? 169 ALA B C   1 -0.288 0.477  0.075  
ATOM   4349  O  O   . ALA B 1 180 ? -31.025 53.216  30.548  1    114.75 ? 169 ALA B O   1 -0.284 0.488  0.076  
ATOM   4350  C  CB  . ALA B 1 180 ? -33.871 52.492  29.884  1    120.94 ? 169 ALA B CB  1 -0.31  0.481  0.075  
ATOM   4351  N  N   . LYS B 1 181 ? -30.674 51.253  29.457  1    117.02 ? 170 LYS B N   1 -0.281 0.47   0.074  
ATOM   4352  C  CA  . LYS B 1 181 ? -29.262 51.501  29.17   1    119.17 ? 170 LYS B CA  1 -0.268 0.472  0.073  
ATOM   4353  C  C   . LYS B 1 181 ? -29.03  52.654  28.201  1    116.26 ? 170 LYS B C   1 -0.266 0.483  0.07   
ATOM   4354  O  O   . LYS B 1 181 ? -27.888 53.115  28.072  1    112.71 ? 170 LYS B O   1 -0.256 0.487  0.07   
ATOM   4355  C  CB  . LYS B 1 181 ? -28.605 50.237  28.61   1    119.5  ? 170 LYS B CB  1 -0.262 0.46   0.071  
ATOM   4356  C  CG  . LYS B 1 181 ? -28.224 49.222  29.665  1    122.19 ? 170 LYS B CG  1 -0.259 0.451  0.074  
ATOM   4357  C  CD  . LYS B 1 181 ? -27.312 48.138  29.107  1    130.47 ? 170 LYS B CD  1 -0.25  0.441  0.073  
ATOM   4358  C  CE  . LYS B 1 181 ? -25.834 48.505  29.252  1    133.05 ? 170 LYS B CE  1 -0.237 0.445  0.073  
ATOM   4359  N  NZ  . LYS B 1 181 ? -25.236 49.076  27.999  1    132.11 ? 170 LYS B NZ  1 -0.231 0.45   0.07   
ATOM   4360  N  N   . ALA B 1 182 ? -30.073 53.124  27.52   1    115.65 ? 171 ALA B N   1 -0.276 0.487  0.069  
ATOM   4361  C  CA  . ALA B 1 182 ? -29.945 54.199  26.538  1    105.6  ? 171 ALA B CA  1 -0.274 0.497  0.066  
ATOM   4362  C  C   . ALA B 1 182 ? -31.234 55.007  26.613  1    104.48 ? 171 ALA B C   1 -0.286 0.504  0.066  
ATOM   4363  O  O   . ALA B 1 182 ? -32.302 54.517  26.229  1    107.94 ? 171 ALA B O   1 -0.296 0.5    0.065  
ATOM   4364  C  CB  . ALA B 1 182 ? -29.704 53.629  25.149  1    98.71  ? 171 ALA B CB  1 -0.272 0.491  0.063  
ATOM   4365  N  N   . HIS B 1 183 ? -31.142 56.229  27.128  1    102.02 ? 172 HIS B N   1 -0.285 0.515  0.068  
ATOM   4366  C  CA  . HIS B 1 183 ? -32.3   56.958  27.644  1    105.15 ? 172 HIS B CA  1 -0.296 0.522  0.069  
ATOM   4367  C  C   . HIS B 1 183 ? -32.46  58.265  26.878  1    105.17 ? 172 HIS B C   1 -0.297 0.534  0.067  
ATOM   4368  O  O   . HIS B 1 183 ? -31.616 59.163  26.995  1    105.34 ? 172 HIS B O   1 -0.29  0.542  0.067  
ATOM   4369  C  CB  . HIS B 1 183 ? -32.123 57.226  29.138  1    108.85 ? 172 HIS B CB  1 -0.294 0.524  0.073  
ATOM   4370  C  CG  . HIS B 1 183 ? -33.339 56.96   29.972  1    111.54 ? 172 HIS B CG  1 -0.306 0.522  0.075  
ATOM   4371  N  ND1 . HIS B 1 183 ? -34.406 57.833  30.044  1    111.29 ? 172 HIS B ND1 1 -0.315 0.53   0.075  
ATOM   4372  C  CD2 . HIS B 1 183 ? -33.629 55.943  30.819  1    113.2  ? 172 HIS B CD2 1 -0.308 0.513  0.077  
ATOM   4373  C  CE1 . HIS B 1 183 ? -35.312 57.355  30.881  1    109.08 ? 172 HIS B CE1 1 -0.324 0.526  0.077  
ATOM   4374  N  NE2 . HIS B 1 183 ? -34.866 56.207  31.363  1    113.89 ? 172 HIS B NE2 1 -0.32  0.515  0.078  
ATOM   4375  N  N   . PHE B 1 184 ? -33.544 58.378  26.111  1    102.32 ? 173 PHE B N   1 -0.307 0.535  0.065  
ATOM   4376  C  CA  . PHE B 1 184 ? -33.904 59.609  25.41   1    106.21 ? 173 PHE B CA  1 -0.311 0.546  0.063  
ATOM   4377  C  C   . PHE B 1 184 ? -35.152 60.164  26.093  1    105.66 ? 173 PHE B C   1 -0.322 0.551  0.065  
ATOM   4378  O  O   . PHE B 1 184 ? -36.23  59.571  25.987  1    109.7  ? 173 PHE B O   1 -0.332 0.546  0.065  
ATOM   4379  C  CB  . PHE B 1 184 ? -34.154 59.347  23.918  1    99.48  ? 173 PHE B CB  1 -0.313 0.544  0.06   
ATOM   4380  C  CG  . PHE B 1 184 ? -33.038 58.594  23.237  1    98.82  ? 173 PHE B CG  1 -0.303 0.537  0.058  
ATOM   4381  C  CD1 . PHE B 1 184 ? -32.959 57.21   23.324  1    99.81  ? 173 PHE B CD1 1 -0.302 0.524  0.058  
ATOM   4382  C  CD2 . PHE B 1 184 ? -32.073 59.266  22.507  1    99.51  ? 173 PHE B CD2 1 -0.294 0.543  0.056  
ATOM   4383  C  CE1 . PHE B 1 184 ? -31.931 56.508  22.712  1    94.24  ? 173 PHE B CE1 1 -0.293 0.518  0.057  
ATOM   4384  C  CE2 . PHE B 1 184 ? -31.04  58.575  21.885  1    97.86  ? 173 PHE B CE2 1 -0.284 0.537  0.055  
ATOM   4385  C  CZ  . PHE B 1 184 ? -30.966 57.192  21.995  1    95.83  ? 173 PHE B CZ  1 -0.284 0.524  0.055  
ATOM   4386  N  N   . SER B 1 185 ? -35.017 61.284  26.801  1    97.59  ? 174 SER B N   1 -0.321 0.562  0.067  
ATOM   4387  C  CA  . SER B 1 185 ? -36.15  61.866  27.514  1    103.73 ? 174 SER B CA  1 -0.331 0.567  0.069  
ATOM   4388  C  C   . SER B 1 185 ? -36.435 63.28   27.022  1    101.52 ? 174 SER B C   1 -0.334 0.58   0.067  
ATOM   4389  O  O   . SER B 1 185 ? -35.506 64.051  26.738  1    98.74  ? 174 SER B O   1 -0.325 0.587  0.067  
ATOM   4390  C  CB  . SER B 1 185 ? -35.906 61.893  29.023  1    103.04 ? 174 SER B CB  1 -0.329 0.567  0.072  
ATOM   4391  O  OG  . SER B 1 185 ? -34.856 62.787  29.335  1    108.75 ? 174 SER B OG  1 -0.319 0.575  0.073  
ATOM   4392  N  N   . PHE B 1 186 ? -37.722 63.623  26.965  1    96.71  ? 175 PHE B N   1 -0.346 0.583  0.067  
ATOM   4393  C  CA  . PHE B 1 186 ? -38.19  64.884  26.408  1    99.4   ? 175 PHE B CA  1 -0.35  0.595  0.066  
ATOM   4394  C  C   . PHE B 1 186 ? -39.001 65.647  27.45   1    95.71  ? 175 PHE B C   1 -0.357 0.602  0.069  
ATOM   4395  O  O   . PHE B 1 186 ? -40.085 65.206  27.851  1    87.63  ? 175 PHE B O   1 -0.367 0.598  0.07   
ATOM   4396  C  CB  . PHE B 1 186 ? -39.034 64.642  25.147  1    98.15  ? 175 PHE B CB  1 -0.358 0.592  0.063  
ATOM   4397  C  CG  . PHE B 1 186 ? -38.281 63.975  24.046  1    97.45  ? 175 PHE B CG  1 -0.351 0.586  0.06   
ATOM   4398  C  CD1 . PHE B 1 186 ? -38.046 62.606  24.064  1    102.21 ? 175 PHE B CD1 1 -0.349 0.574  0.06   
ATOM   4399  C  CD2 . PHE B 1 186 ? -37.783 64.721  22.994  1    102.33 ? 175 PHE B CD2 1 -0.346 0.593  0.057  
ATOM   4400  C  CE1 . PHE B 1 186 ? -37.326 61.995  23.044  1    104.12 ? 175 PHE B CE1 1 -0.342 0.568  0.058  
ATOM   4401  C  CE2 . PHE B 1 186 ? -37.074 64.121  21.971  1    100.64 ? 175 PHE B CE2 1 -0.34  0.588  0.055  
ATOM   4402  C  CZ  . PHE B 1 186 ? -36.844 62.758  21.995  1    101.94 ? 175 PHE B CZ  1 -0.338 0.575  0.055  
ATOM   4403  N  N   . GLY B 1 187 ? -38.496 66.814  27.856  1    89.85  ? 176 GLY B N   1 -0.353 0.612  0.07   
ATOM   4404  C  CA  . GLY B 1 187 ? -39.218 67.651  28.798  1    90.96  ? 176 GLY B CA  1 -0.359 0.62   0.072  
ATOM   4405  C  C   . GLY B 1 187 ? -38.595 69.015  28.989  1    100.54 ? 176 GLY B C   1 -0.354 0.632  0.072  
ATOM   4406  O  O   . GLY B 1 187 ? -38.012 69.567  28.039  1    102.15 ? 176 GLY B O   1 -0.348 0.638  0.07   
ATOM   4407  N  N   . LEU B 1 188 ? -38.69  69.605  30.24   1    93.64  ? 177 LEU B N   1 -0.355 0.638  0.076  
ATOM   4408  C  CA  . LEU B 1 188 ? -38.189 70.96   30.401  1    88.46  ? 177 LEU B CA  1 -0.35  0.65   0.076  
ATOM   4409  C  C   . LEU B 1 188 ? -36.668 70.935  30.509  1    89.53  ? 177 LEU B C   1 -0.336 0.65   0.076  
ATOM   4410  O  O   . LEU B 1 188 ? -36.098 69.935  30.943  1    88.38  ? 177 LEU B O   1 -0.331 0.641  0.077  
ATOM   4411  C  CB  . LEU B 1 188 ? -38.804 71.598  31.618  1    93.06  ? 177 LEU B CB  1 -0.356 0.656  0.079  
ATOM   4412  C  CG  . LEU B 1 188 ? -40.311 71.724  31.459  1    96.96  ? 177 LEU B CG  1 -0.369 0.657  0.079  
ATOM   4413  C  CD1 . LEU B 1 188 ? -41.008 71.271  32.723  1    105.13 ? 177 LEU B CD1 1 -0.376 0.653  0.082  
ATOM   4414  C  CD2 . LEU B 1 188 ? -40.616 73.171  31.168  1    105.79 ? 177 LEU B CD2 1 -0.372 0.671  0.078  
ATOM   4415  N  N   . PRO B 1 189 ? -35.979 71.987  30.067  1    91.69  ? 178 PRO B N   1 -0.33  0.66   0.075  
ATOM   4416  C  CA  . PRO B 1 189 ? -34.526 71.893  29.893  1    97.71  ? 178 PRO B CA  1 -0.316 0.659  0.075  
ATOM   4417  C  C   . PRO B 1 189 ? -33.779 72.046  31.22   1    99.76  ? 178 PRO B C   1 -0.31  0.66   0.078  
ATOM   4418  O  O   . PRO B 1 189 ? -34.341 72.376  32.266  1    98.9   ? 178 PRO B O   1 -0.315 0.663  0.081  
ATOM   4419  C  CB  . PRO B 1 189 ? -34.197 73.041  28.923  1    90.66  ? 178 PRO B CB  1 -0.313 0.669  0.072  
ATOM   4420  C  CG  . PRO B 1 189 ? -35.507 73.702  28.609  1    96.18  ? 178 PRO B CG  1 -0.325 0.675  0.071  
ATOM   4421  C  CD  . PRO B 1 189 ? -36.459 73.326  29.705  1    90.14  ? 178 PRO B CD  1 -0.334 0.672  0.074  
ATOM   4422  N  N   . SER B 1 190 ? -32.464 71.824  31.144  1    98.79  ? 179 SER B N   1 -0.298 0.658  0.078  
ATOM   4423  C  CA  . SER B 1 190 ? -31.638 71.736  32.341  1    94.33  ? 179 SER B CA  1 -0.29  0.657  0.081  
ATOM   4424  C  C   . SER B 1 190 ? -30.352 72.551  32.295  1    99.45  ? 179 SER B C   1 -0.278 0.665  0.081  
ATOM   4425  O  O   . SER B 1 190 ? -29.918 73.03   33.355  1    103.98 ? 179 SER B O   1 -0.274 0.669  0.083  
ATOM   4426  C  CB  . SER B 1 190 ? -31.3   70.278  32.631  1    96.51  ? 179 SER B CB  1 -0.287 0.644  0.081  
ATOM   4427  O  OG  . SER B 1 190 ? -30.177 69.883  31.858  1    104.08 ? 179 SER B OG  1 -0.277 0.64   0.08   
ATOM   4428  N  N   . HIS B 1 191 ? -29.722 72.754  31.147  1    97.89  ? 180 HIS B N   1 -0.272 0.667  0.078  
ATOM   4429  C  CA  . HIS B 1 191 ? -28.314 73.135  31.178  1    102.27 ? 180 HIS B CA  1 -0.259 0.67   0.078  
ATOM   4430  C  C   . HIS B 1 191 ? -28.047 74.602  31.573  1    100.02 ? 180 HIS B C   1 -0.257 0.684  0.079  
ATOM   4431  O  O   . HIS B 1 191 ? -26.873 74.977  31.706  1    98.78  ? 180 HIS B O   1 -0.246 0.687  0.079  
ATOM   4432  C  CB  . HIS B 1 191 ? -27.636 72.783  29.824  1    102.83 ? 180 HIS B CB  1 -0.253 0.667  0.074  
ATOM   4433  C  CG  . HIS B 1 191 ? -28.02  73.661  28.674  1    101.05 ? 180 HIS B CG  1 -0.257 0.675  0.072  
ATOM   4434  N  ND1 . HIS B 1 191 ? -27.089 74.192  27.804  1    96.21  ? 180 HIS B ND1 1 -0.248 0.68   0.069  
ATOM   4435  C  CD2 . HIS B 1 191 ? -29.23  74.087  28.238  1    99.46  ? 180 HIS B CD2 1 -0.268 0.679  0.071  
ATOM   4436  C  CE1 . HIS B 1 191 ? -27.709 74.922  26.895  1    94.48  ? 180 HIS B CE1 1 -0.254 0.687  0.067  
ATOM   4437  N  NE2 . HIS B 1 191 ? -29.009 74.875  27.136  1    94.6   ? 180 HIS B NE2 1 -0.266 0.686  0.068  
ATOM   4438  N  N   . HIS B 1 192 ? -29.067 75.436  31.811  1    96.19  ? 181 HIS B N   1 -0.266 0.691  0.079  
ATOM   4439  C  CA  . HIS B 1 192 ? -28.816 76.781  32.326  1    94.78  ? 181 HIS B CA  1 -0.264 0.704  0.081  
ATOM   4440  C  C   . HIS B 1 192 ? -29.113 76.91   33.81   1    104    ? 181 HIS B C   1 -0.267 0.705  0.084  
ATOM   4441  O  O   . HIS B 1 192 ? -28.781 77.944  34.405  1    102.05 ? 181 HIS B O   1 -0.264 0.714  0.086  
ATOM   4442  C  CB  . HIS B 1 192 ? -29.642 77.832  31.578  1    103.54 ? 181 HIS B CB  1 -0.272 0.713  0.079  
ATOM   4443  C  CG  . HIS B 1 192 ? -29.296 77.968  30.126  1    108.35 ? 181 HIS B CG  1 -0.268 0.715  0.075  
ATOM   4444  N  ND1 . HIS B 1 192 ? -28.003 78.149  29.681  1    104.2  ? 181 HIS B ND1 1 -0.257 0.716  0.074  
ATOM   4445  C  CD2 . HIS B 1 192 ? -30.079 77.959  29.019  1    97.79  ? 181 HIS B CD2 1 -0.276 0.714  0.072  
ATOM   4446  C  CE1 . HIS B 1 192 ? -28.002 78.236  28.364  1    95.8   ? 181 HIS B CE1 1 -0.257 0.717  0.071  
ATOM   4447  N  NE2 . HIS B 1 192 ? -29.248 78.122  27.938  1    98.57  ? 181 HIS B NE2 1 -0.268 0.716  0.07   
ATOM   4448  N  N   . ALA B 1 193 ? -29.755 75.906  34.41   1    108.49 ? 182 ALA B N   1 -0.273 0.696  0.086  
ATOM   4449  C  CA  . ALA B 1 193 ? -29.96  75.9    35.852  1    94.93  ? 182 ALA B CA  1 -0.275 0.696  0.09   
ATOM   4450  C  C   . ALA B 1 193 ? -28.613 75.853  36.55   1    93.49  ? 182 ALA B C   1 -0.262 0.695  0.091  
ATOM   4451  O  O   . ALA B 1 193 ? -27.752 75.031  36.22   1    90.1   ? 182 ALA B O   1 -0.254 0.688  0.09   
ATOM   4452  C  CB  . ALA B 1 193 ? -30.823 74.709  36.266  1    90.95  ? 182 ALA B CB  1 -0.282 0.685  0.091  
ATOM   4453  N  N   . TYR B 1 194 ? -28.425 76.765  37.492  1    100.9  ? 183 TYR B N   1 -0.26  0.703  0.094  
ATOM   4454  C  CA  . TYR B 1 194 ? -27.227 76.821  38.315  1    100.93 ? 183 TYR B CA  1 -0.25  0.704  0.096  
ATOM   4455  C  C   . TYR B 1 194 ? -27.454 76.092  39.635  1    103.07 ? 183 TYR B C   1 -0.252 0.697  0.099  
ATOM   4456  O  O   . TYR B 1 194 ? -28.586 75.77   40.017  1    98.46  ? 183 TYR B O   1 -0.262 0.694  0.1    
ATOM   4457  C  CB  . TYR B 1 194 ? -26.833 78.27   38.596  1    102.45 ? 183 TYR B CB  1 -0.246 0.717  0.096  
ATOM   4458  C  CG  . TYR B 1 194 ? -26.135 78.985  37.475  1    96.74  ? 183 TYR B CG  1 -0.24  0.724  0.094  
ATOM   4459  C  CD1 . TYR B 1 194 ? -26.856 79.74   36.559  1    98.9   ? 183 TYR B CD1 1 -0.246 0.731  0.091  
ATOM   4460  C  CD2 . TYR B 1 194 ? -24.746 78.935  37.352  1    98.02  ? 183 TYR B CD2 1 -0.227 0.723  0.093  
ATOM   4461  C  CE1 . TYR B 1 194 ? -26.214 80.411  35.527  1    99.54  ? 183 TYR B CE1 1 -0.24  0.737  0.089  
ATOM   4462  C  CE2 . TYR B 1 194 ? -24.096 79.597  36.343  1    100.94 ? 183 TYR B CE2 1 -0.221 0.729  0.091  
ATOM   4463  C  CZ  . TYR B 1 194 ? -24.832 80.335  35.429  1    102.59 ? 183 TYR B CZ  1 -0.228 0.736  0.088  
ATOM   4464  O  OH  . TYR B 1 194 ? -24.181 81.004  34.426  1    100.42 ? 183 TYR B OH  1 -0.222 0.742  0.086  
ATOM   4465  N  N   . THR B 1 195 ? -26.345 75.88   40.354  1    107.25 ? 184 THR B N   1 -0.241 0.695  0.101  
ATOM   4466  C  CA  . THR B 1 195 ? -26.348 75.226  41.665  1    106.18 ? 184 THR B CA  1 -0.241 0.689  0.104  
ATOM   4467  C  C   . THR B 1 195 ? -27.345 75.843  42.644  1    105.79 ? 184 THR B C   1 -0.251 0.695  0.106  
ATOM   4468  O  O   . THR B 1 195 ? -27.72  75.195  43.629  1    107.7  ? 184 THR B O   1 -0.254 0.689  0.109  
ATOM   4469  C  CB  . THR B 1 195 ? -24.937 75.307  42.277  1    110.79 ? 184 THR B CB  1 -0.229 0.69   0.106  
ATOM   4470  O  OG1 . THR B 1 195 ? -23.945 75.368  41.231  1    114.04 ? 184 THR B OG1 1 -0.219 0.691  0.103  
ATOM   4471  C  CG2 . THR B 1 195 ? -24.654 74.123  43.22   1    107.23 ? 184 THR B CG2 1 -0.226 0.679  0.108  
ATOM   4472  N  N   . GLN B 1 196 ? -27.774 77.092  42.397  1    107.12 ? 185 GLN B N   1 -0.255 0.706  0.106  
ATOM   4473  C  CA  . GLN B 1 196 ? -28.57  77.834  43.37   1    106.44 ? 185 GLN B CA  1 -0.262 0.713  0.108  
ATOM   4474  C  C   . GLN B 1 196 ? -29.513 78.845  42.718  1    111.27 ? 185 GLN B C   1 -0.27  0.723  0.107  
ATOM   4475  O  O   . GLN B 1 196 ? -30.013 79.738  43.415  1    107.71 ? 185 GLN B O   1 -0.275 0.731  0.108  
ATOM   4476  C  CB  . GLN B 1 196 ? -27.65  78.593  44.336  1    108.28 ? 185 GLN B CB  1 -0.253 0.72   0.111  
ATOM   4477  C  CG  . GLN B 1 196 ? -26.829 79.712  43.682  1    108.95 ? 185 GLN B CG  1 -0.246 0.73   0.109  
ATOM   4478  C  CD  . GLN B 1 196 ? -25.648 79.218  42.836  1    109.71 ? 185 GLN B CD  1 -0.235 0.726  0.107  
ATOM   4479  O  OE1 . GLN B 1 196 ? -25.824 78.543  41.812  1    109.66 ? 185 GLN B OE1 1 -0.237 0.72   0.104  
ATOM   4480  N  NE2 . GLN B 1 196 ? -24.436 79.58   43.253  1    104.25 ? 185 GLN B NE2 1 -0.224 0.729  0.108  
ATOM   4481  N  N   . MET B 1 197 ? -29.773 78.728  41.411  1    105.77 ? 186 MET B N   1 -0.273 0.721  0.103  
ATOM   4482  C  CA  . MET B 1 197 ? -30.488 79.757  40.668  1    103.62 ? 186 MET B CA  1 -0.279 0.731  0.102  
ATOM   4483  C  C   . MET B 1 197 ? -30.972 79.175  39.344  1    107.43 ? 186 MET B C   1 -0.284 0.726  0.098  
ATOM   4484  O  O   . MET B 1 197 ? -30.303 78.326  38.741  1    104.68 ? 186 MET B O   1 -0.278 0.718  0.097  
ATOM   4485  C  CB  . MET B 1 197 ? -29.574 80.968  40.44   1    99.33  ? 186 MET B CB  1 -0.271 0.742  0.101  
ATOM   4486  C  CG  . MET B 1 197 ? -30.203 82.149  39.702  1    97.22  ? 186 MET B CG  1 -0.277 0.753  0.099  
ATOM   4487  S  SD  . MET B 1 197 ? -29.001 83.504  39.462  1    113.13 ? 186 MET B SD  1 -0.266 0.765  0.099  
ATOM   4488  C  CE  . MET B 1 197 ? -27.748 82.765  38.382  1    98.37  ? 186 MET B CE  1 -0.254 0.758  0.096  
ATOM   4489  N  N   . GLY B 1 198 ? -32.136 79.637  38.898  1    101.23 ? 187 GLY B N   1 -0.294 0.73   0.097  
ATOM   4490  C  CA  . GLY B 1 198 ? -32.671 79.241  37.608  1    102.97 ? 187 GLY B CA  1 -0.299 0.726  0.094  
ATOM   4491  C  C   . GLY B 1 198 ? -32.377 80.292  36.549  1    106.8  ? 187 GLY B C   1 -0.297 0.736  0.091  
ATOM   4492  O  O   . GLY B 1 198 ? -32.208 81.471  36.855  1    106.51 ? 187 GLY B O   1 -0.295 0.747  0.092  
ATOM   4493  N  N   . SER B 1 199 ? -32.308 79.865  35.291  1    103.49 ? 188 SER B N   1 -0.296 0.732  0.088  
ATOM   4494  C  CA  . SER B 1 199 ? -32.075 80.828  34.223  1    104.78 ? 188 SER B CA  1 -0.294 0.741  0.085  
ATOM   4495  C  C   . SER B 1 199 ? -32.433 80.215  32.88   1    110.32 ? 188 SER B C   1 -0.297 0.735  0.082  
ATOM   4496  O  O   . SER B 1 199 ? -32.302 79.001  32.675  1    105.67 ? 188 SER B O   1 -0.296 0.724  0.082  
ATOM   4497  C  CB  . SER B 1 199 ? -30.62  81.314  34.186  1    100.89 ? 188 SER B CB  1 -0.281 0.745  0.085  
ATOM   4498  O  OG  . SER B 1 199 ? -29.73  80.236  33.96   1    97.07  ? 188 SER B OG  1 -0.272 0.735  0.085  
ATOM   4499  N  N   . GLY B 1 200 ? -32.879 81.083  31.97   1    112.83 ? 189 GLY B N   1 -0.301 0.743  0.08   
ATOM   4500  C  CA  . GLY B 1 200 ? -33.069 80.721  30.584  1    110.05 ? 189 GLY B CA  1 -0.303 0.74   0.076  
ATOM   4501  C  C   . GLY B 1 200 ? -33.857 79.447  30.389  1    107.9  ? 189 GLY B C   1 -0.31  0.728  0.076  
ATOM   4502  O  O   . GLY B 1 200 ? -33.358 78.479  29.792  1    103.73 ? 189 GLY B O   1 -0.306 0.719  0.074  
ATOM   4503  N  N   . PHE B 1 201 ? -35.09  79.448  30.898  1    101.99 ? 190 PHE B N   1 -0.322 0.728  0.077  
ATOM   4504  C  CA  . PHE B 1 201 ? -36.052 78.359  30.789  1    105.99 ? 190 PHE B CA  1 -0.33  0.718  0.077  
ATOM   4505  C  C   . PHE B 1 201 ? -35.672 77.145  31.634  1    105.05 ? 190 PHE B C   1 -0.327 0.707  0.079  
ATOM   4506  O  O   . PHE B 1 201 ? -36.411 76.151  31.624  1    103.48 ? 190 PHE B O   1 -0.334 0.698  0.079  
ATOM   4507  C  CB  . PHE B 1 201 ? -36.259 77.895  29.332  1    109.56 ? 190 PHE B CB  1 -0.332 0.714  0.073  
ATOM   4508  C  CG  . PHE B 1 201 ? -36.257 79.018  28.31   1    111.25 ? 190 PHE B CG  1 -0.332 0.724  0.071  
ATOM   4509  C  CD1 . PHE B 1 201 ? -37.267 79.97   28.298  1    113    ? 190 PHE B CD1 1 -0.342 0.733  0.071  
ATOM   4510  C  CD2 . PHE B 1 201 ? -35.258 79.099  27.345  1    107.96 ? 190 PHE B CD2 1 -0.323 0.725  0.068  
ATOM   4511  C  CE1 . PHE B 1 201 ? -37.276 80.991  27.356  1    113.49 ? 190 PHE B CE1 1 -0.342 0.742  0.068  
ATOM   4512  C  CE2 . PHE B 1 201 ? -35.262 80.119  26.398  1    108.44 ? 190 PHE B CE2 1 -0.323 0.734  0.066  
ATOM   4513  C  CZ  . PHE B 1 201 ? -36.27  81.064  26.403  1    112.54 ? 190 PHE B CZ  1 -0.332 0.743  0.066  
ATOM   4514  N  N   . CYS B 1 202 ? -34.557 77.182  32.361  1    103.44 ? 191 CYS B N   1 -0.317 0.707  0.081  
ATOM   4515  C  CA  . CYS B 1 202 ? -34.076 76.048  33.145  1    104.38 ? 191 CYS B CA  1 -0.312 0.697  0.083  
ATOM   4516  C  C   . CYS B 1 202 ? -34.314 76.286  34.629  1    104.55 ? 191 CYS B C   1 -0.314 0.699  0.086  
ATOM   4517  O  O   . CYS B 1 202 ? -33.993 77.362  35.147  1    107.04 ? 191 CYS B O   1 -0.312 0.709  0.088  
ATOM   4518  C  CB  . CYS B 1 202 ? -32.59  75.814  32.889  1    103.35 ? 191 CYS B CB  1 -0.299 0.695  0.082  
ATOM   4519  S  SG  . CYS B 1 202 ? -32.297 74.929  31.367  1    102.37 ? 191 CYS B SG  1 -0.296 0.687  0.078  
ATOM   4520  N  N   . LEU B 1 203 ? -34.851 75.277  35.315  1    102.77 ? 192 LEU B N   1 -0.319 0.69   0.088  
ATOM   4521  C  CA  . LEU B 1 203 ? -35.208 75.389  36.731  1    102.96 ? 192 LEU B CA  1 -0.323 0.691  0.092  
ATOM   4522  C  C   . LEU B 1 203 ? -34.404 74.478  37.643  1    102.13 ? 192 LEU B C   1 -0.315 0.683  0.094  
ATOM   4523  O  O   . LEU B 1 203 ? -34.015 74.894  38.742  1    104.86 ? 192 LEU B O   1 -0.312 0.686  0.097  
ATOM   4524  C  CB  . LEU B 1 203 ? -36.697 75.1    36.92   1    90.89  ? 192 LEU B CB  1 -0.336 0.688  0.092  
ATOM   4525  C  CG  . LEU B 1 203 ? -37.519 76.319  36.544  1    94.28  ? 192 LEU B CG  1 -0.344 0.699  0.091  
ATOM   4526  C  CD1 . LEU B 1 203 ? -38.965 76.028  36.84   1    97.01  ? 192 LEU B CD1 1 -0.357 0.697  0.092  
ATOM   4527  C  CD2 . LEU B 1 203 ? -37.017 77.541  37.317  1    98.56  ? 192 LEU B CD2 1 -0.339 0.711  0.093  
ATOM   4528  N  N   . ILE B 1 204 ? -34.179 73.231  37.239  1    95.95  ? 193 ILE B N   1 -0.313 0.671  0.093  
ATOM   4529  C  CA  . ILE B 1 204 ? -33.249 72.345  37.922  1    96.25  ? 193 ILE B CA  1 -0.305 0.663  0.095  
ATOM   4530  C  C   . ILE B 1 204 ? -32.436 71.641  36.857  1    94.14  ? 193 ILE B C   1 -0.297 0.657  0.092  
ATOM   4531  O  O   . ILE B 1 204 ? -32.862 71.49   35.712  1    102.89 ? 193 ILE B O   1 -0.301 0.655  0.089  
ATOM   4532  C  CB  . ILE B 1 204 ? -33.929 71.307  38.841  1    100.58 ? 193 ILE B CB  1 -0.311 0.653  0.097  
ATOM   4533  C  CG1 . ILE B 1 204 ? -35.016 70.563  38.064  1    98.51  ? 193 ILE B CG1 1 -0.321 0.647  0.095  
ATOM   4534  C  CG2 . ILE B 1 204 ? -34.417 71.967  40.171  1    97.45  ? 193 ILE B CG2 1 -0.315 0.66   0.1    
ATOM   4535  C  CD1 . ILE B 1 204 ? -35.838 69.635  38.879  1    98.44  ? 193 ILE B CD1 1 -0.328 0.638  0.097  
ATOM   4536  N  N   . ASN B 1 205 ? -31.25  71.211  37.242  1    93.57  ? 194 ASN B N   1 -0.286 0.653  0.093  
ATOM   4537  C  CA  . ASN B 1 205 ? -30.3   70.681  36.287  1    93.72  ? 194 ASN B CA  1 -0.278 0.648  0.091  
ATOM   4538  C  C   . ASN B 1 205 ? -30.374 69.157  36.359  1    93.96  ? 194 ASN B C   1 -0.278 0.634  0.091  
ATOM   4539  O  O   . ASN B 1 205 ? -29.586 68.486  37.032  1    89.75  ? 194 ASN B O   1 -0.271 0.628  0.092  
ATOM   4540  C  CB  . ASN B 1 205 ? -28.917 71.238  36.576  1    95.2   ? 194 ASN B CB  1 -0.265 0.653  0.091  
ATOM   4541  C  CG  . ASN B 1 205 ? -27.915 70.853  35.534  1    103.03 ? 194 ASN B CG  1 -0.256 0.649  0.089  
ATOM   4542  O  OD1 . ASN B 1 205 ? -27.507 71.674  34.705  1    105.77 ? 194 ASN B OD1 1 -0.252 0.657  0.087  
ATOM   4543  N  ND2 . ASN B 1 205 ? -27.501 69.599  35.569  1    104.24 ? 194 ASN B ND2 1 -0.252 0.638  0.089  
ATOM   4544  N  N   . LYS B 1 206 ? -31.359 68.612  35.635  1    94.86  ? 195 LYS B N   1 -0.287 0.629  0.089  
ATOM   4545  C  CA  . LYS B 1 206 ? -31.601 67.172  35.614  1    93.65  ? 195 LYS B CA  1 -0.29  0.616  0.089  
ATOM   4546  C  C   . LYS B 1 206 ? -30.413 66.369  35.087  1    93.04  ? 195 LYS B C   1 -0.279 0.608  0.088  
ATOM   4547  O  O   . LYS B 1 206 ? -30.336 65.164  35.343  1    91.52  ? 195 LYS B O   1 -0.278 0.597  0.088  
ATOM   4548  C  CB  . LYS B 1 206 ? -32.848 66.856  34.773  1    86.64  ? 195 LYS B CB  1 -0.301 0.613  0.087  
ATOM   4549  C  CG  . LYS B 1 206 ? -33.224 65.385  34.782  1    83.49  ? 195 LYS B CG  1 -0.304 0.599  0.087  
ATOM   4550  C  CD  . LYS B 1 206 ? -34.324 65.081  33.799  1    100.07 ? 195 LYS B CD  1 -0.315 0.596  0.084  
ATOM   4551  C  CE  . LYS B 1 206 ? -34.452 63.576  33.643  1    106.23 ? 195 LYS B CE  1 -0.316 0.583  0.084  
ATOM   4552  N  NZ  . LYS B 1 206 ? -35.14  63.198  32.389  1    100.39 ? 195 LYS B NZ  1 -0.322 0.579  0.081  
ATOM   4553  N  N   . THR B 1 207 ? -29.483 66.983  34.358  1    92.33  ? 196 THR B N   1 -0.27  0.614  0.086  
ATOM   4554  C  CA  . THR B 1 207 ? -28.363 66.178  33.886  1    97.95  ? 196 THR B CA  1 -0.26  0.606  0.085  
ATOM   4555  C  C   . THR B 1 207 ? -27.412 65.84   35.026  1    96.04  ? 196 THR B C   1 -0.251 0.603  0.087  
ATOM   4556  O  O   . THR B 1 207 ? -27.012 64.681  35.183  1    96.73  ? 196 THR B O   1 -0.248 0.593  0.088  
ATOM   4557  C  CB  . THR B 1 207 ? -27.613 66.877  32.753  1    103.06 ? 196 THR B CB  1 -0.253 0.613  0.082  
ATOM   4558  O  OG1 . THR B 1 207 ? -28.54  67.304  31.749  1    94.51  ? 196 THR B OG1 1 -0.262 0.617  0.079  
ATOM   4559  C  CG2 . THR B 1 207 ? -26.637 65.909  32.132  1    94.29  ? 196 THR B CG2 1 -0.244 0.604  0.08   
ATOM   4560  N  N   . ALA B 1 208 ? -27.065 66.828  35.849  1    103.01 ? 197 ALA B N   1 -0.248 0.612  0.09   
ATOM   4561  C  CA  . ALA B 1 208 ? -26.12  66.593  36.94   1    99.73  ? 197 ALA B CA  1 -0.239 0.61   0.092  
ATOM   4562  C  C   . ALA B 1 208 ? -26.687 65.632  37.984  1    98.46  ? 197 ALA B C   1 -0.245 0.601  0.095  
ATOM   4563  O  O   . ALA B 1 208 ? -25.957 64.779  38.505  1    95.54  ? 197 ALA B O   1 -0.238 0.594  0.096  
ATOM   4564  C  CB  . ALA B 1 208 ? -25.723 67.927  37.57   1    86.45  ? 197 ALA B CB  1 -0.236 0.622  0.094  
ATOM   4565  N  N   . MET B 1 209 ? -27.982 65.743  38.302  1    97.6   ? 198 MET B N   1 -0.256 0.602  0.096  
ATOM   4566  C  CA  . MET B 1 209 ? -28.573 64.781  39.233  1    98.32  ? 198 MET B CA  1 -0.262 0.594  0.098  
ATOM   4567  C  C   . MET B 1 209 ? -28.417 63.368  38.694  1    99.18  ? 198 MET B C   1 -0.26  0.581  0.097  
ATOM   4568  O  O   . MET B 1 209 ? -27.97  62.464  39.408  1    100.26 ? 198 MET B O   1 -0.256 0.572  0.098  
ATOM   4569  C  CB  . MET B 1 209 ? -30.047 65.098  39.488  1    92.91  ? 198 MET B CB  1 -0.275 0.597  0.099  
ATOM   4570  C  CG  . MET B 1 209 ? -30.293 66.405  40.187  1    88.44  ? 198 MET B CG  1 -0.278 0.609  0.1    
ATOM   4571  S  SD  . MET B 1 209 ? -32.042 66.83   40.091  1    95.54  ? 198 MET B SD  1 -0.294 0.612  0.1    
ATOM   4572  C  CE  . MET B 1 209 ? -32.84  65.275  40.525  1    85.08  ? 198 MET B CE  1 -0.301 0.598  0.101  
ATOM   4573  N  N   . LEU B 1 210 ? -28.759 63.174  37.419  1    101.29 ? 199 LEU B N   1 -0.264 0.579  0.093  
ATOM   4574  C  CA  . LEU B 1 210 ? -28.503 61.905  36.745  1    101.23 ? 199 LEU B CA  1 -0.261 0.567  0.092  
ATOM   4575  C  C   . LEU B 1 210 ? -27.057 61.457  36.948  1    102.1  ? 199 LEU B C   1 -0.248 0.563  0.092  
ATOM   4576  O  O   . LEU B 1 210 ? -26.791 60.289  37.264  1    99.09  ? 199 LEU B O   1 -0.246 0.552  0.093  
ATOM   4577  C  CB  . LEU B 1 210 ? -28.834 62.049  35.254  1    105.91 ? 199 LEU B CB  1 -0.264 0.569  0.088  
ATOM   4578  C  CG  . LEU B 1 210 ? -30.166 61.489  34.738  1    105.11 ? 199 LEU B CG  1 -0.276 0.563  0.087  
ATOM   4579  C  CD1 . LEU B 1 210 ? -30.086 59.976  34.765  1    116.27 ? 199 LEU B CD1 1 -0.276 0.55   0.087  
ATOM   4580  C  CD2 . LEU B 1 210 ? -31.365 61.97   35.546  1    93.78  ? 199 LEU B CD2 1 -0.287 0.568  0.089  
ATOM   4581  N  N   . MET B 1 211 ? -26.108 62.388  36.792  1    104.06 ? 200 MET B N   1 -0.239 0.572  0.092  
ATOM   4582  C  CA  . MET B 1 211 ? -24.698 62.066  37.004  1    106.31 ? 200 MET B CA  1 -0.226 0.569  0.092  
ATOM   4583  C  C   . MET B 1 211 ? -24.403 61.747  38.464  1    105.36 ? 200 MET B C   1 -0.224 0.566  0.096  
ATOM   4584  O  O   . MET B 1 211 ? -23.457 61.006  38.763  1    104.61 ? 200 MET B O   1 -0.215 0.559  0.097  
ATOM   4585  C  CB  . MET B 1 211 ? -23.818 63.224  36.537  1    108.56 ? 200 MET B CB  1 -0.218 0.579  0.091  
ATOM   4586  C  CG  . MET B 1 211 ? -24.068 63.688  35.115  1    103.27 ? 200 MET B CG  1 -0.221 0.584  0.088  
ATOM   4587  S  SD  . MET B 1 211 ? -22.844 64.946  34.708  1    104.9  ? 200 MET B SD  1 -0.209 0.595  0.087  
ATOM   4588  C  CE  . MET B 1 211 ? -21.332 64.223  35.367  1    98.56  ? 200 MET B CE  1 -0.195 0.589  0.088  
ATOM   4589  N  N   . LYS B 1 212 ? -25.186 62.3    39.389  1    105.68 ? 201 LYS B N   1 -0.231 0.571  0.098  
ATOM   4590  C  CA  . LYS B 1 212 ? -24.988 61.953  40.792  1    111.05 ? 201 LYS B CA  1 -0.229 0.568  0.102  
ATOM   4591  C  C   . LYS B 1 212 ? -25.31  60.482  41.023  1    110.46 ? 201 LYS B C   1 -0.232 0.554  0.102  
ATOM   4592  O  O   . LYS B 1 212 ? -24.489 59.735  41.569  1    112.2  ? 201 LYS B O   1 -0.224 0.547  0.104  
ATOM   4593  C  CB  . LYS B 1 212 ? -25.831 62.867  41.692  1    107.45 ? 201 LYS B CB  1 -0.237 0.576  0.104  
ATOM   4594  C  CG  . LYS B 1 212 ? -25.738 62.57   43.163  1    102.63 ? 201 LYS B CG  1 -0.236 0.573  0.108  
ATOM   4595  C  CD  . LYS B 1 212 ? -24.298 62.376  43.596  1    109.14 ? 201 LYS B CD  1 -0.223 0.572  0.109  
ATOM   4596  C  CE  . LYS B 1 212 ? -23.549 63.694  43.622  1    113.66 ? 201 LYS B CE  1 -0.216 0.584  0.109  
ATOM   4597  N  NZ  . LYS B 1 212 ? -22.488 63.706  44.692  1    119.83 ? 201 LYS B NZ  1 -0.206 0.584  0.112  
ATOM   4598  N  N   . GLN B 1 213 ? -26.483 60.041  40.56   1    108.2  ? 202 GLN B N   1 -0.243 0.55   0.101  
ATOM   4599  C  CA  . GLN B 1 213 ? -26.889 58.647  40.682  1    109.1  ? 202 GLN B CA  1 -0.246 0.537  0.102  
ATOM   4600  C  C   . GLN B 1 213 ? -25.929 57.685  39.989  1    111.64 ? 202 GLN B C   1 -0.238 0.529  0.1    
ATOM   4601  O  O   . GLN B 1 213 ? -25.986 56.481  40.257  1    115.3  ? 202 GLN B O   1 -0.238 0.518  0.101  
ATOM   4602  C  CB  . GLN B 1 213 ? -28.308 58.482  40.126  1    102.57 ? 202 GLN B CB  1 -0.259 0.536  0.1    
ATOM   4603  C  CG  . GLN B 1 213 ? -28.97  57.174  40.474  1    102.2  ? 202 GLN B CG  1 -0.265 0.524  0.101  
ATOM   4604  C  CD  . GLN B 1 213 ? -28.816 56.842  41.934  1    115.72 ? 202 GLN B CD  1 -0.264 0.521  0.105  
ATOM   4605  O  OE1 . GLN B 1 213 ? -28.95  57.711  42.806  1    117.37 ? 202 GLN B OE1 1 -0.265 0.529  0.107  
ATOM   4606  N  NE2 . GLN B 1 213 ? -28.51  55.581  42.216  1    118.7  ? 202 GLN B NE2 1 -0.261 0.509  0.105  
ATOM   4607  N  N   . ALA B 1 214 ? -25.045 58.175  39.121  1    109.92 ? 203 ALA B N   1 -0.23  0.533  0.098  
ATOM   4608  C  CA  . ALA B 1 214 ? -24.088 57.29   38.471  1    113.4  ? 203 ALA B CA  1 -0.221 0.525  0.096  
ATOM   4609  C  C   . ALA B 1 214 ? -22.852 57.041  39.33   1    118.1  ? 203 ALA B C   1 -0.209 0.523  0.098  
ATOM   4610  O  O   . ALA B 1 214 ? -22.314 55.928  39.326  1    123.72 ? 203 ALA B O   1 -0.204 0.513  0.098  
ATOM   4611  C  CB  . ALA B 1 214 ? -23.676 57.863  37.112  1    113.51 ? 203 ALA B CB  1 -0.217 0.53   0.093  
ATOM   4612  N  N   . GLU B 1 215 ? -22.389 58.056  40.071  1    118.28 ? 204 GLU B N   1 -0.205 0.532  0.1    
ATOM   4613  C  CA  . GLU B 1 215 ? -21.185 57.91   40.886  1    118.78 ? 204 GLU B CA  1 -0.194 0.531  0.102  
ATOM   4614  C  C   . GLU B 1 215 ? -21.431 57.125  42.175  1    121.53 ? 204 GLU B C   1 -0.196 0.524  0.105  
ATOM   4615  O  O   . GLU B 1 215 ? -20.465 56.704  42.825  1    125.07 ? 204 GLU B O   1 -0.188 0.52   0.107  
ATOM   4616  C  CB  . GLU B 1 215 ? -20.596 59.288  41.222  1    117.27 ? 204 GLU B CB  1 -0.189 0.543  0.103  
ATOM   4617  C  CG  . GLU B 1 215 ? -20.997 59.775  42.618  1    117.79 ? 204 GLU B CG  1 -0.192 0.548  0.106  
ATOM   4618  C  CD  . GLU B 1 215 ? -20.32  61.064  43.063  1    121.8  ? 204 GLU B CD  1 -0.186 0.56   0.108  
ATOM   4619  O  OE1 . GLU B 1 215 ? -21.038 61.977  43.524  1    125.32 ? 204 GLU B OE1 1 -0.193 0.568  0.109  
ATOM   4620  O  OE2 . GLU B 1 215 ? -19.077 61.16   42.98   1    121.5  ? 204 GLU B OE2 1 -0.175 0.56   0.107  
ATOM   4621  N  N   . LEU B 1 216 ? -22.69  56.895  42.552  1    119.78 ? 205 LEU B N   1 -0.208 0.521  0.106  
ATOM   4622  C  CA  . LEU B 1 216 ? -23.011 56.106  43.734  1    113.37 ? 205 LEU B CA  1 -0.211 0.514  0.109  
ATOM   4623  C  C   . LEU B 1 216 ? -23.358 54.657  43.403  1    120.6  ? 205 LEU B C   1 -0.214 0.501  0.108  
ATOM   4624  O  O   . LEU B 1 216 ? -22.844 53.743  44.055  1    125.13 ? 205 LEU B O   1 -0.209 0.493  0.11   
ATOM   4625  C  CB  . LEU B 1 216 ? -24.163 56.762  44.506  1    106.51 ? 205 LEU B CB  1 -0.221 0.52   0.111  
ATOM   4626  C  CG  . LEU B 1 216 ? -23.986 58.255  44.833  1    102.33 ? 205 LEU B CG  1 -0.22  0.534  0.112  
ATOM   4627  C  CD1 . LEU B 1 216 ? -25.102 58.793  45.705  1    91.32  ? 205 LEU B CD1 1 -0.23  0.539  0.114  
ATOM   4628  C  CD2 . LEU B 1 216 ? -22.647 58.526  45.479  1    97.74  ? 205 LEU B CD2 1 -0.208 0.536  0.114  
ATOM   4629  N  N   . SER B 1 217 ? -24.17  54.416  42.361  1    119.89 ? 206 SER B N   1 -0.221 0.499  0.106  
ATOM   4630  C  CA  . SER B 1 217 ? -24.722 53.094  42.051  1    120.8  ? 206 SER B CA  1 -0.227 0.487  0.105  
ATOM   4631  C  C   . SER B 1 217 ? -23.696 52.094  41.531  1    123.75 ? 206 SER B C   1 -0.217 0.477  0.104  
ATOM   4632  O  O   . SER B 1 217 ? -24.089 50.973  41.177  1    119.15 ? 206 SER B O   1 -0.221 0.467  0.103  
ATOM   4633  C  CB  . SER B 1 217 ? -25.842 53.22   41.021  1    120.88 ? 206 SER B CB  1 -0.237 0.488  0.102  
ATOM   4634  O  OG  . SER B 1 217 ? -26.73  54.262  41.373  1    123.75 ? 206 SER B OG  1 -0.245 0.497  0.103  
ATOM   4635  N  N   . SER B 1 218 ? -22.418 52.449  41.469  1    126.72 ? 207 SER B N   1 -0.205 0.481  0.104  
ATOM   4636  C  CA  . SER B 1 218 ? -21.378 51.565  40.973  1    128.67 ? 207 SER B CA  1 -0.196 0.473  0.102  
ATOM   4637  C  C   . SER B 1 218 ? -20.368 51.256  42.08   1    133.69 ? 207 SER B C   1 -0.187 0.47   0.105  
ATOM   4638  O  O   . SER B 1 218 ? -20.381 51.853  43.166  1    126.88 ? 207 SER B O   1 -0.187 0.475  0.108  
ATOM   4639  C  CB  . SER B 1 218 ? -20.679 52.186  39.749  1    126.17 ? 207 SER B CB  1 -0.19  0.478  0.099  
ATOM   4640  O  OG  . SER B 1 218 ? -19.472 51.506  39.437  1    128.96 ? 207 SER B OG  1 -0.178 0.472  0.098  
ATOM   4641  N  N   . ALA B 1 219 ? -19.489 50.289  41.79   1    136.27 ? 208 ALA B N   1 -0.179 0.461  0.104  
ATOM   4642  C  CA  . ALA B 1 219 ? -18.337 50.009  42.64   1    137.32 ? 208 ALA B CA  1 -0.168 0.458  0.106  
ATOM   4643  C  C   . ALA B 1 219 ? -17.353 51.171  42.553  1    134.83 ? 208 ALA B C   1 -0.159 0.469  0.106  
ATOM   4644  O  O   . ALA B 1 219 ? -17.295 52.018  43.456  1    121.34 ? 208 ALA B O   1 -0.158 0.477  0.109  
ATOM   4645  C  CB  . ALA B 1 219 ? -17.666 48.691  42.231  1    135.67 ? 208 ALA B CB  1 -0.162 0.446  0.105  
ATOM   4646  N  N   . GLN B 1 220 ? -16.579 51.218  41.451  1    136.53 ? 209 GLN B N   1 -0.152 0.469  0.103  
ATOM   4647  C  CA  . GLN B 1 220 ? -15.799 52.382  41.062  1    135.38 ? 209 GLN B CA  1 -0.145 0.48   0.103  
ATOM   4648  C  C   . GLN B 1 220 ? -16.701 53.408  40.375  1    130.4  ? 209 GLN B C   1 -0.153 0.489  0.101  
ATOM   4649  O  O   . GLN B 1 220 ? -17.722 53.047  39.784  1    125.32 ? 209 GLN B O   1 -0.162 0.486  0.099  
ATOM   4650  C  CB  . GLN B 1 220 ? -14.672 51.974  40.113  1    138.14 ? 209 GLN B CB  1 -0.134 0.476  0.1    
ATOM   4651  C  CG  . GLN B 1 220 ? -13.416 51.467  40.812  1    144.18 ? 209 GLN B CG  1 -0.123 0.472  0.102  
ATOM   4652  C  CD  . GLN B 1 220 ? -12.568 52.598  41.382  1    148.29 ? 209 GLN B CD  1 -0.115 0.482  0.103  
ATOM   4653  O  OE1 . GLN B 1 220 ? -12.311 52.654  42.587  1    145.03 ? 209 GLN B OE1 1 -0.113 0.483  0.106  
ATOM   4654  N  NE2 . GLN B 1 220 ? -12.125 53.505  40.511  1    148.88 ? 209 GLN B NE2 1 -0.111 0.49   0.101  
ATOM   4655  N  N   . PRO B 1 221 ? -16.363 54.693  40.451  1    132.44 ? 210 PRO B N   1 -0.15  0.501  0.101  
ATOM   4656  C  CA  . PRO B 1 221 ? -17.096 55.695  39.667  1    131.05 ? 210 PRO B CA  1 -0.157 0.51   0.099  
ATOM   4657  C  C   . PRO B 1 221 ? -16.73  55.59   38.198  1    128.43 ? 210 PRO B C   1 -0.153 0.509  0.095  
ATOM   4658  O  O   . PRO B 1 221 ? -15.553 55.396  37.851  1    124.12 ? 210 PRO B O   1 -0.143 0.508  0.095  
ATOM   4659  C  CB  . PRO B 1 221 ? -16.63  57.029  40.271  1    126.96 ? 210 PRO B CB  1 -0.152 0.523  0.101  
ATOM   4660  C  CG  . PRO B 1 221 ? -15.256 56.733  40.762  1    133.31 ? 210 PRO B CG  1 -0.14  0.52   0.102  
ATOM   4661  C  CD  . PRO B 1 221 ? -15.322 55.313  41.292  1    133.88 ? 210 PRO B CD  1 -0.14  0.507  0.103  
ATOM   4662  N  N   . PRO B 1 222 ? -17.707 55.687  37.3    1    124.36 ? 211 PRO B N   1 -0.162 0.51   0.093  
ATOM   4663  C  CA  . PRO B 1 222 ? -17.391 55.627  35.873  1    121.08 ? 211 PRO B CA  1 -0.159 0.51   0.09   
ATOM   4664  C  C   . PRO B 1 222 ? -16.685 56.898  35.434  1    117.94 ? 211 PRO B C   1 -0.153 0.521  0.088  
ATOM   4665  O  O   . PRO B 1 222 ? -16.657 57.905  36.146  1    114.44 ? 211 PRO B O   1 -0.153 0.531  0.09   
ATOM   4666  C  CB  . PRO B 1 222 ? -18.764 55.485  35.205  1    118.51 ? 211 PRO B CB  1 -0.172 0.508  0.088  
ATOM   4667  C  CG  . PRO B 1 222 ? -19.704 56.154  36.15   1    117.34 ? 211 PRO B CG  1 -0.181 0.515  0.09   
ATOM   4668  C  CD  . PRO B 1 222 ? -19.147 55.904  37.54   1    123.14 ? 211 PRO B CD  1 -0.175 0.512  0.094  
ATOM   4669  N  N   . LYS B 1 223 ? -16.073 56.828  34.255  1    120.67 ? 212 LYS B N   1 -0.147 0.521  0.086  
ATOM   4670  C  CA  . LYS B 1 223 ? -15.574 58.031  33.608  1    116.29 ? 212 LYS B CA  1 -0.143 0.532  0.084  
ATOM   4671  C  C   . LYS B 1 223 ? -16.735 58.718  32.899  1    115.1  ? 212 LYS B C   1 -0.153 0.538  0.082  
ATOM   4672  O  O   . LYS B 1 223 ? -17.647 58.057  32.394  1    118.41 ? 212 LYS B O   1 -0.162 0.532  0.081  
ATOM   4673  C  CB  . LYS B 1 223 ? -14.448 57.699  32.627  1    111.42 ? 212 LYS B CB  1 -0.132 0.529  0.081  
ATOM   4674  C  CG  . LYS B 1 223 ? -13.931 58.936  31.903  1    122.29 ? 212 LYS B CG  1 -0.128 0.54   0.08   
ATOM   4675  C  CD  . LYS B 1 223 ? -12.608 58.704  31.187  1    131.75 ? 212 LYS B CD  1 -0.116 0.538  0.078  
ATOM   4676  C  CE  . LYS B 1 223 ? -12.042 60.023  30.648  1    131.91 ? 212 LYS B CE  1 -0.11  0.55   0.077  
ATOM   4677  N  NZ  . LYS B 1 223 ? -12.209 60.175  29.168  1    129.86 ? 212 LYS B NZ  1 -0.112 0.551  0.073  
ATOM   4678  N  N   . PHE B 1 224 ? -16.725 60.046  32.89   1    111.34 ? 213 PHE B N   1 -0.153 0.55   0.082  
ATOM   4679  C  CA  . PHE B 1 224 ? -17.836 60.812  32.344  1    113.43 ? 213 PHE B CA  1 -0.163 0.557  0.081  
ATOM   4680  C  C   . PHE B 1 224 ? -17.428 61.562  31.075  1    111.16 ? 213 PHE B C   1 -0.16  0.564  0.078  
ATOM   4681  O  O   . PHE B 1 224 ? -16.324 62.113  30.988  1    108.41 ? 213 PHE B O   1 -0.15  0.569  0.077  
ATOM   4682  C  CB  . PHE B 1 224 ? -18.375 61.79   33.392  1    109.08 ? 213 PHE B CB  1 -0.168 0.566  0.083  
ATOM   4683  C  CG  . PHE B 1 224 ? -19.101 61.124  34.526  1    112.05 ? 213 PHE B CG  1 -0.175 0.56   0.086  
ATOM   4684  C  CD1 . PHE B 1 224 ? -18.409 60.629  35.617  1    116.31 ? 213 PHE B CD1 1 -0.169 0.556  0.089  
ATOM   4685  C  CD2 . PHE B 1 224 ? -20.483 61.003  34.509  1    112.62 ? 213 PHE B CD2 1 -0.188 0.559  0.086  
ATOM   4686  C  CE1 . PHE B 1 224 ? -19.079 60.023  36.66   1    112.43 ? 213 PHE B CE1 1 -0.175 0.55   0.092  
ATOM   4687  C  CE2 . PHE B 1 224 ? -21.16  60.401  35.548  1    103.58 ? 213 PHE B CE2 1 -0.194 0.554  0.089  
ATOM   4688  C  CZ  . PHE B 1 224 ? -20.455 59.909  36.622  1    111.95 ? 213 PHE B CZ  1 -0.187 0.549  0.091  
ATOM   4689  N  N   . VAL B 1 225 ? -18.324 61.563  30.085  1    110.74 ? 214 VAL B N   1 -0.168 0.564  0.075  
ATOM   4690  C  CA  . VAL B 1 225 ? -18.191 62.377  28.878  1    113.94 ? 214 VAL B CA  1 -0.167 0.572  0.072  
ATOM   4691  C  C   . VAL B 1 225 ? -19.537 63.049  28.624  1    108.89 ? 214 VAL B C   1 -0.179 0.578  0.071  
ATOM   4692  O  O   . VAL B 1 225 ? -20.576 62.377  28.583  1    106.9  ? 214 VAL B O   1 -0.189 0.572  0.071  
ATOM   4693  C  CB  . VAL B 1 225 ? -17.757 61.558  27.633  1    112.71 ? 214 VAL B CB  1 -0.163 0.564  0.069  
ATOM   4694  C  CG1 . VAL B 1 225 ? -17.609 62.462  26.414  1    105.73 ? 214 VAL B CG1 1 -0.161 0.572  0.066  
ATOM   4695  C  CG2 . VAL B 1 225 ? -16.447 60.824  27.867  1    114.82 ? 214 VAL B CG2 1 -0.151 0.557  0.07   
ATOM   4696  N  N   . ILE B 1 226 ? -19.514 64.365  28.449  1    104.18 ? 215 ILE B N   1 -0.179 0.59   0.071  
ATOM   4697  C  CA  . ILE B 1 226 ? -20.699 65.145  28.119  1    102.37 ? 215 ILE B CA  1 -0.19  0.597  0.07   
ATOM   4698  C  C   . ILE B 1 226 ? -20.434 65.842  26.792  1    103.86 ? 215 ILE B C   1 -0.187 0.603  0.067  
ATOM   4699  O  O   . ILE B 1 226 ? -19.343 66.387  26.582  1    106.8  ? 215 ILE B O   1 -0.177 0.608  0.066  
ATOM   4700  C  CB  . ILE B 1 226 ? -21.026 66.144  29.247  1    101.68 ? 215 ILE B CB  1 -0.193 0.606  0.073  
ATOM   4701  C  CG1 . ILE B 1 226 ? -21.458 65.371  30.483  1    104.03 ? 215 ILE B CG1 1 -0.197 0.599  0.076  
ATOM   4702  C  CG2 . ILE B 1 226 ? -22.157 67.085  28.88   1    99.5   ? 215 ILE B CG2 1 -0.203 0.615  0.072  
ATOM   4703  C  CD1 . ILE B 1 226 ? -21.23  66.112  31.784  1    107.58 ? 215 ILE B CD1 1 -0.195 0.606  0.079  
ATOM   4704  N  N   . ILE B 1 227 ? -21.403 65.78   25.88   1    103.34 ? 216 ILE B N   1 -0.196 0.603  0.065  
ATOM   4705  C  CA  . ILE B 1 227 ? -21.38  66.541  24.633  1    97.86  ? 216 ILE B CA  1 -0.196 0.61   0.062  
ATOM   4706  C  C   . ILE B 1 227 ? -22.706 67.281  24.571  1    97.55  ? 216 ILE B C   1 -0.208 0.617  0.061  
ATOM   4707  O  O   . ILE B 1 227 ? -23.758 66.652  24.394  1    102.26 ? 216 ILE B O   1 -0.218 0.611  0.061  
ATOM   4708  C  CB  . ILE B 1 227 ? -21.203 65.659  23.384  1    102    ? 216 ILE B CB  1 -0.194 0.602  0.058  
ATOM   4709  C  CG1 . ILE B 1 227 ? -19.993 64.731  23.494  1    103.99 ? 216 ILE B CG1 1 -0.183 0.593  0.059  
ATOM   4710  C  CG2 . ILE B 1 227 ? -21.065 66.529  22.111  1    99.31  ? 216 ILE B CG2 1 -0.193 0.61   0.055  
ATOM   4711  C  CD1 . ILE B 1 227 ? -19.698 63.985  22.173  1    101.2  ? 216 ILE B CD1 1 -0.181 0.586  0.055  
ATOM   4712  N  N   . GLY B 1 228 ? -22.667 68.605  24.698  1    93.98  ? 217 GLY B N   1 -0.208 0.629  0.062  
ATOM   4713  C  CA  . GLY B 1 228 ? -23.906 69.366  24.728  1    100.26 ? 217 GLY B CA  1 -0.219 0.636  0.062  
ATOM   4714  C  C   . GLY B 1 228 ? -24.099 70.271  23.529  1    99.55  ? 217 GLY B C   1 -0.221 0.644  0.059  
ATOM   4715  O  O   . GLY B 1 228 ? -23.491 71.346  23.468  1    97.28  ? 217 GLY B O   1 -0.215 0.654  0.059  
ATOM   4716  N  N   . THR B 1 229 ? -24.962 69.885  22.584  1    103.34 ? 218 THR B N   1 -0.229 0.64   0.056  
ATOM   4717  C  CA  . THR B 1 229 ? -24.946 70.518  21.264  1    102.72 ? 218 THR B CA  1 -0.229 0.646  0.053  
ATOM   4718  C  C   . THR B 1 229 ? -25.981 71.635  21.078  1    100.72 ? 218 THR B C   1 -0.238 0.656  0.053  
ATOM   4719  O  O   . THR B 1 229 ? -26.041 72.216  19.99   1    102.08 ? 218 THR B O   1 -0.239 0.662  0.05   
ATOM   4720  C  CB  . THR B 1 229 ? -25.086 69.45   20.151  1    96.18  ? 218 THR B CB  1 -0.23  0.636  0.05   
ATOM   4721  O  OG1 . THR B 1 229 ? -26.431 68.957  20.057  1    99.74  ? 218 THR B OG1 1 -0.242 0.632  0.05   
ATOM   4722  C  CG2 . THR B 1 229 ? -24.147 68.27   20.403  1    94.39  ? 218 THR B CG2 1 -0.221 0.626  0.051  
ATOM   4723  N  N   . ASP B 1 230 ? -26.777 71.967  22.1    1    95.22  ? 219 ASP B N   1 -0.245 0.66   0.055  
ATOM   4724  C  CA  . ASP B 1 230 ? -27.551 73.212  22.103  1    95.51  ? 219 ASP B CA  1 -0.252 0.671  0.055  
ATOM   4725  C  C   . ASP B 1 230 ? -26.659 74.389  21.707  1    98.3   ? 219 ASP B C   1 -0.244 0.682  0.054  
ATOM   4726  O  O   . ASP B 1 230 ? -25.487 74.45   22.085  1    105.52 ? 219 ASP B O   1 -0.234 0.682  0.055  
ATOM   4727  C  CB  . ASP B 1 230 ? -28.141 73.406  23.509  1    97.18  ? 219 ASP B CB  1 -0.258 0.673  0.059  
ATOM   4728  C  CG  . ASP B 1 230 ? -29.125 74.57   23.616  1    93.51  ? 219 ASP B CG  1 -0.267 0.683  0.059  
ATOM   4729  O  OD1 . ASP B 1 230 ? -28.684 75.75   23.616  1    88.56  ? 219 ASP B OD1 1 -0.263 0.694  0.059  
ATOM   4730  O  OD2 . ASP B 1 230 ? -30.34  74.285  23.761  1    88.9   ? 219 ASP B OD2 1 -0.278 0.681  0.059  
ATOM   4731  N  N   . VAL B 1 231 ? -27.194 75.33   20.931  1    94.82  ? 220 VAL B N   1 -0.249 0.69   0.052  
ATOM   4732  C  CA  . VAL B 1 231 ? -26.312 76.409  20.5    1    99.91  ? 220 VAL B CA  1 -0.241 0.7    0.051  
ATOM   4733  C  C   . VAL B 1 231 ? -25.961 77.367  21.635  1    100.32 ? 220 VAL B C   1 -0.238 0.709  0.054  
ATOM   4734  O  O   . VAL B 1 231 ? -24.949 78.077  21.548  1    99.28  ? 220 VAL B O   1 -0.229 0.716  0.054  
ATOM   4735  C  CB  . VAL B 1 231 ? -26.91  77.184  19.327  1    98.11  ? 220 VAL B CB  1 -0.247 0.707  0.048  
ATOM   4736  C  CG1 . VAL B 1 231 ? -28.105 78.102  19.846  1    100.33 ? 220 VAL B CG1 1 -0.258 0.716  0.05   
ATOM   4737  C  CG2 . VAL B 1 231 ? -25.702 77.831  18.481  1    101.45 ? 220 VAL B CG2 1 -0.236 0.713  0.046  
ATOM   4738  N  N   . ASN B 1 232 ? -26.76  77.417  22.694  1    102.35 ? 221 ASN B N   1 -0.245 0.709  0.057  
ATOM   4739  C  CA  . ASN B 1 232 ? -26.392 78.177  23.879  1    102.88 ? 221 ASN B CA  1 -0.242 0.716  0.06   
ATOM   4740  C  C   . ASN B 1 232 ? -25.494 77.337  24.789  1    98.62  ? 221 ASN B C   1 -0.234 0.709  0.062  
ATOM   4741  O  O   . ASN B 1 232 ? -25.533 76.102  24.765  1    98.07  ? 221 ASN B O   1 -0.234 0.697  0.062  
ATOM   4742  C  CB  . ASN B 1 232 ? -27.657 78.647  24.587  1    100.75 ? 221 ASN B CB  1 -0.253 0.721  0.061  
ATOM   4743  C  CG  . ASN B 1 232 ? -28.668 79.232  23.601  1    104.8  ? 221 ASN B CG  1 -0.263 0.726  0.059  
ATOM   4744  O  OD1 . ASN B 1 232 ? -29.544 78.522  23.099  1    101.27 ? 221 ASN B OD1 1 -0.271 0.72   0.058  
ATOM   4745  N  ND2 . ASN B 1 232 ? -28.511 80.519  23.278  1    104.59 ? 221 ASN B ND2 1 -0.261 0.738  0.058  
ATOM   4746  N  N   . ARG B 1 233 ? -24.646 78.024  25.556  1    100.78 ? 222 ARG B N   1 -0.226 0.715  0.064  
ATOM   4747  C  CA  . ARG B 1 233 ? -23.62  77.366  26.359  1    97.03  ? 222 ARG B CA  1 -0.216 0.709  0.066  
ATOM   4748  C  C   . ARG B 1 233 ? -24.232 76.61   27.529  1    94.44  ? 222 ARG B C   1 -0.222 0.702  0.069  
ATOM   4749  O  O   . ARG B 1 233 ? -25.265 77.006  28.069  1    98.42  ? 222 ARG B O   1 -0.232 0.706  0.07   
ATOM   4750  C  CB  . ARG B 1 233 ? -22.631 78.397  26.891  1    93.05  ? 222 ARG B CB  1 -0.207 0.718  0.067  
ATOM   4751  C  CG  . ARG B 1 233 ? -21.484 77.796  27.659  1    97.96  ? 222 ARG B CG  1 -0.197 0.713  0.069  
ATOM   4752  C  CD  . ARG B 1 233 ? -20.709 78.859  28.404  1    101.32 ? 222 ARG B CD  1 -0.19  0.723  0.071  
ATOM   4753  N  NE  . ARG B 1 233 ? -19.867 78.282  29.446  1    104.84 ? 222 ARG B NE  1 -0.182 0.717  0.074  
ATOM   4754  C  CZ  . ARG B 1 233 ? -19.539 78.91   30.568  1    104.99 ? 222 ARG B CZ  1 -0.179 0.723  0.076  
ATOM   4755  N  NH1 . ARG B 1 233 ? -19.998 80.123  30.841  1    101.05 ? 222 ARG B NH1 1 -0.183 0.734  0.077  
ATOM   4756  N  NH2 . ARG B 1 233 ? -18.731 78.306  31.44   1    102.95 ? 222 ARG B NH2 1 -0.172 0.718  0.078  
ATOM   4757  N  N   . ASP B 1 234 ? -23.587 75.509  27.928  1    92.28  ? 223 ASP B N   1 -0.216 0.692  0.07   
ATOM   4758  C  CA  . ASP B 1 234 ? -23.95  74.834  29.184  1    102.33 ? 223 ASP B CA  1 -0.219 0.686  0.073  
ATOM   4759  C  C   . ASP B 1 234 ? -23.324 75.547  30.391  1    104.19 ? 223 ASP B C   1 -0.214 0.692  0.076  
ATOM   4760  O  O   . ASP B 1 234 ? -22.554 74.972  31.167  1    101.28 ? 223 ASP B O   1 -0.207 0.687  0.078  
ATOM   4761  C  CB  . ASP B 1 234 ? -23.53  73.37   29.179  1    99.49  ? 223 ASP B CB  1 -0.216 0.672  0.073  
ATOM   4762  C  CG  . ASP B 1 234 ? -23.74  72.711  27.865  1    105.62 ? 223 ASP B CG  1 -0.218 0.666  0.07   
ATOM   4763  O  OD1 . ASP B 1 234 ? -24.522 73.263  27.059  1    110.41 ? 223 ASP B OD1 1 -0.225 0.671  0.068  
ATOM   4764  O  OD2 . ASP B 1 234 ? -23.114 71.647  27.637  1    106.77 ? 223 ASP B OD2 1 -0.212 0.657  0.069  
ATOM   4765  N  N   . ASN B 1 235 ? -23.66  76.835  30.543  1    100.02 ? 224 ASN B N   1 -0.217 0.704  0.076  
ATOM   4766  C  CA  . ASN B 1 235 ? -23.06  77.594  31.628  1    95.74  ? 224 ASN B CA  1 -0.211 0.711  0.079  
ATOM   4767  C  C   . ASN B 1 235 ? -23.539 77.062  32.969  1    99.85  ? 224 ASN B C   1 -0.216 0.706  0.082  
ATOM   4768  O  O   . ASN B 1 235 ? -22.729 76.856  33.876  1    99.94  ? 224 ASN B O   1 -0.208 0.704  0.085  
ATOM   4769  C  CB  . ASN B 1 235 ? -23.353 79.088  31.465  1    94.52  ? 224 ASN B CB  1 -0.214 0.725  0.079  
ATOM   4770  C  CG  . ASN B 1 235 ? -24.832 79.398  31.374  1    96.5   ? 224 ASN B CG  1 -0.228 0.728  0.078  
ATOM   4771  O  OD1 . ASN B 1 235 ? -25.665 78.491  31.31   1    98.27  ? 224 ASN B OD1 1 -0.235 0.719  0.078  
ATOM   4772  N  ND2 . ASN B 1 235 ? -25.169 80.689  31.354  1    92.7   ? 224 ASN B ND2 1 -0.231 0.739  0.078  
ATOM   4773  N  N   . GLY B 1 236 ? -24.839 76.778  33.093  1    99.84  ? 225 GLY B N   1 -0.228 0.704  0.083  
ATOM   4774  C  CA  . GLY B 1 236 ? -25.361 76.305  34.364  1    101.18 ? 225 GLY B CA  1 -0.232 0.699  0.086  
ATOM   4775  C  C   . GLY B 1 236 ? -24.786 74.959  34.761  1    101.93 ? 225 GLY B C   1 -0.227 0.687  0.087  
ATOM   4776  O  O   . GLY B 1 236 ? -24.263 74.788  35.864  1    99.23  ? 225 GLY B O   1 -0.222 0.685  0.09   
ATOM   4777  N  N   . LEU B 1 237 ? -24.854 73.987  33.851  1    105.52 ? 226 LEU B N   1 -0.228 0.678  0.085  
ATOM   4778  C  CA  . LEU B 1 237 ? -24.288 72.675  34.128  1    104.91 ? 226 LEU B CA  1 -0.223 0.666  0.085  
ATOM   4779  C  C   . LEU B 1 237 ? -22.788 72.739  34.404  1    101.51 ? 226 LEU B C   1 -0.209 0.667  0.086  
ATOM   4780  O  O   . LEU B 1 237 ? -22.257 71.851  35.079  1    97.83  ? 226 LEU B O   1 -0.204 0.658  0.088  
ATOM   4781  C  CB  . LEU B 1 237 ? -24.575 71.736  32.958  1    100.49 ? 226 LEU B CB  1 -0.225 0.657  0.082  
ATOM   4782  C  CG  . LEU B 1 237 ? -24.148 70.286  33.184  1    107.02 ? 226 LEU B CG  1 -0.221 0.644  0.083  
ATOM   4783  C  CD1 . LEU B 1 237 ? -25.341 69.417  33.453  1    102.95 ? 226 LEU B CD1 1 -0.232 0.636  0.084  
ATOM   4784  C  CD2 . LEU B 1 237 ? -23.372 69.774  31.984  1    105.18 ? 226 LEU B CD2 1 -0.214 0.639  0.08   
ATOM   4785  N  N   . CYS B 1 238 ? -22.099 73.77   33.909  1    101.18 ? 227 CYS B N   1 -0.203 0.676  0.085  
ATOM   4786  C  CA  . CYS B 1 238 ? -20.652 73.848  34.08   1    105.51 ? 227 CYS B CA  1 -0.189 0.677  0.085  
ATOM   4787  C  C   . CYS B 1 238 ? -20.281 74.394  35.457  1    109.67 ? 227 CYS B C   1 -0.186 0.682  0.089  
ATOM   4788  O  O   . CYS B 1 238 ? -19.309 73.937  36.073  1    110.66 ? 227 CYS B O   1 -0.177 0.678  0.09   
ATOM   4789  C  CB  . CYS B 1 238 ? -20.038 74.705  32.966  1    105.39 ? 227 CYS B CB  1 -0.184 0.685  0.082  
ATOM   4790  S  SG  . CYS B 1 238 ? -18.222 74.704  32.914  1    107.07 ? 227 CYS B SG  1 -0.167 0.685  0.082  
ATOM   4791  N  N   . ASP B 1 239 ? -21.032 75.376  35.957  1    106.65 ? 228 ASP B N   1 -0.193 0.691  0.09   
ATOM   4792  C  CA  . ASP B 1 239 ? -20.826 75.79   37.33   1    99.52  ? 228 ASP B CA  1 -0.191 0.695  0.093  
ATOM   4793  C  C   . ASP B 1 239 ? -21.021 74.596  38.254  1    108.11 ? 228 ASP B C   1 -0.193 0.684  0.096  
ATOM   4794  O  O   . ASP B 1 239 ? -20.115 74.226  39.012  1    112.21 ? 228 ASP B O   1 -0.184 0.68   0.097  
ATOM   4795  C  CB  . ASP B 1 239 ? -21.775 76.937  37.692  1    101.81 ? 228 ASP B CB  1 -0.2   0.705  0.094  
ATOM   4796  C  CG  . ASP B 1 239 ? -21.362 77.659  38.994  1    120.15 ? 228 ASP B CG  1 -0.196 0.712  0.097  
ATOM   4797  O  OD1 . ASP B 1 239 ? -20.4   78.466  38.915  1    116.45 ? 228 ASP B OD1 1 -0.187 0.719  0.097  
ATOM   4798  O  OD2 . ASP B 1 239 ? -21.982 77.423  40.084  1    112.04 ? 228 ASP B OD2 1 -0.201 0.71   0.1    
ATOM   4799  N  N   . ILE B 1 240 ? -22.176 73.93   38.139  1    103.6  ? 229 ILE B N   1 -0.203 0.678  0.095  
ATOM   4800  C  CA  . ILE B 1 240 ? -22.52  72.827  39.034  1    96.08  ? 229 ILE B CA  1 -0.206 0.667  0.097  
ATOM   4801  C  C   . ILE B 1 240 ? -21.476 71.723  38.968  1    101.61 ? 229 ILE B C   1 -0.197 0.657  0.097  
ATOM   4802  O  O   . ILE B 1 240 ? -21.175 71.08   39.979  1    101.59 ? 229 ILE B O   1 -0.194 0.651  0.1    
ATOM   4803  C  CB  . ILE B 1 240 ? -23.92  72.287  38.703  1    88.93  ? 229 ILE B CB  1 -0.219 0.662  0.097  
ATOM   4804  C  CG1 . ILE B 1 240 ? -24.963 73.377  38.904  1    91.26  ? 229 ILE B CG1 1 -0.229 0.672  0.097  
ATOM   4805  C  CG2 . ILE B 1 240 ? -24.22  71.031  39.513  1    86.32  ? 229 ILE B CG2 1 -0.222 0.651  0.099  
ATOM   4806  C  CD1 . ILE B 1 240 ? -26.37  72.893  38.699  1    95.17  ? 229 ILE B CD1 1 -0.242 0.668  0.097  
ATOM   4807  N  N   . LEU B 1 241 ? -20.915 71.468  37.778  1    104.79 ? 230 LEU B N   1 -0.192 0.655  0.094  
ATOM   4808  C  CA  . LEU B 1 241 ? -19.896 70.426  37.668  1    105.5  ? 230 LEU B CA  1 -0.182 0.645  0.094  
ATOM   4809  C  C   . LEU B 1 241 ? -18.594 70.877  38.316  1    109.97 ? 230 LEU B C   1 -0.17  0.65   0.096  
ATOM   4810  O  O   . LEU B 1 241 ? -17.986 70.125  39.091  1    113.05 ? 230 LEU B O   1 -0.165 0.643  0.098  
ATOM   4811  C  CB  . LEU B 1 241 ? -19.662 70.032  36.204  1    103.97 ? 230 LEU B CB  1 -0.18  0.642  0.09   
ATOM   4812  C  CG  . LEU B 1 241 ? -20.635 69.063  35.52   1    102.19 ? 230 LEU B CG  1 -0.189 0.633  0.089  
ATOM   4813  C  CD1 . LEU B 1 241 ? -20.213 68.839  34.09   1    111.88 ? 230 LEU B CD1 1 -0.185 0.631  0.085  
ATOM   4814  C  CD2 . LEU B 1 241 ? -20.677 67.737  36.222  1    105.06 ? 230 LEU B CD2 1 -0.189 0.621  0.09   
ATOM   4815  N  N   . ARG B 1 242 ? -18.171 72.114  38.046  1    106.14 ? 231 ARG B N   1 -0.167 0.661  0.095  
ATOM   4816  C  CA  . ARG B 1 242 ? -16.915 72.6    38.608  1    111.94 ? 231 ARG B CA  1 -0.155 0.665  0.096  
ATOM   4817  C  C   . ARG B 1 242 ? -16.969 72.69   40.136  1    117.03 ? 231 ARG B C   1 -0.156 0.666  0.1    
ATOM   4818  O  O   . ARG B 1 242 ? -15.939 72.537  40.808  1    113.23 ? 231 ARG B O   1 -0.146 0.665  0.102  
ATOM   4819  C  CB  . ARG B 1 242 ? -16.581 73.956  38.003  1    106.79 ? 231 ARG B CB  1 -0.152 0.678  0.095  
ATOM   4820  C  CG  . ARG B 1 242 ? -15.191 74.435  38.306  1    109.23 ? 231 ARG B CG  1 -0.139 0.682  0.096  
ATOM   4821  C  CD  . ARG B 1 242 ? -14.991 75.804  37.73   1    114.86 ? 231 ARG B CD  1 -0.137 0.695  0.094  
ATOM   4822  N  NE  . ARG B 1 242 ? -16.213 76.589  37.844  1    117.39 ? 231 ARG B NE  1 -0.149 0.702  0.094  
ATOM   4823  C  CZ  . ARG B 1 242 ? -16.518 77.323  38.901  1    109.5  ? 231 ARG B CZ  1 -0.151 0.709  0.097  
ATOM   4824  N  NH1 . ARG B 1 242 ? -15.693 77.417  39.925  1    102.91 ? 231 ARG B NH1 1 -0.144 0.709  0.1    
ATOM   4825  N  NH2 . ARG B 1 242 ? -17.677 77.974  38.928  1    110.35 ? 231 ARG B NH2 1 -0.162 0.715  0.097  
ATOM   4826  N  N   . HIS B 1 243 ? -18.158 72.928  40.696  1    115.29 ? 232 HIS B N   1 -0.166 0.668  0.102  
ATOM   4827  C  CA  . HIS B 1 243 ? -18.3   73.11   42.141  1    114.52 ? 232 HIS B CA  1 -0.168 0.67   0.105  
ATOM   4828  C  C   . HIS B 1 243 ? -18.323 71.77   42.861  1    113.82 ? 232 HIS B C   1 -0.168 0.658  0.107  
ATOM   4829  O  O   . HIS B 1 243 ? -17.351 71.375  43.512  1    111.26 ? 232 HIS B O   1 -0.159 0.654  0.109  
ATOM   4830  C  CB  . HIS B 1 243 ? -19.573 73.908  42.448  1    109.62 ? 232 HIS B CB  1 -0.179 0.677  0.106  
ATOM   4831  C  CG  . HIS B 1 243 ? -19.341 75.379  42.467  1    117.78 ? 232 HIS B CG  1 -0.177 0.691  0.106  
ATOM   4832  N  ND1 . HIS B 1 243 ? -20.176 76.266  43.11   1    126.77 ? 232 HIS B ND1 1 -0.185 0.699  0.108  
ATOM   4833  C  CD2 . HIS B 1 243 ? -18.335 76.118  41.942  1    121.94 ? 232 HIS B CD2 1 -0.168 0.698  0.105  
ATOM   4834  C  CE1 . HIS B 1 243 ? -19.696 77.491  42.974  1    128.81 ? 232 HIS B CE1 1 -0.18  0.71   0.107  
ATOM   4835  N  NE2 . HIS B 1 243 ? -18.582 77.43   42.267  1    126.47 ? 232 HIS B NE2 1 -0.17  0.71   0.106  
ATOM   4836  N  N   . SER B 1 244 ? -19.427 71.054  42.714  1    111.44 ? 233 SER B N   1 -0.178 0.651  0.107  
ATOM   4837  C  CA  . SER B 1 244 ? -19.724 69.876  43.498  1    105.7  ? 233 SER B CA  1 -0.181 0.64   0.109  
ATOM   4838  C  C   . SER B 1 244 ? -19.114 68.593  42.927  1    109.68 ? 233 SER B C   1 -0.175 0.629  0.107  
ATOM   4839  O  O   . SER B 1 244 ? -18.93  67.63   43.681  1    116.78 ? 233 SER B O   1 -0.173 0.62   0.109  
ATOM   4840  C  CB  . SER B 1 244 ? -21.254 69.765  43.626  1    107.65 ? 233 SER B CB  1 -0.195 0.639  0.109  
ATOM   4841  O  OG  . SER B 1 244 ? -21.898 71.033  43.422  1    99.39  ? 233 SER B OG  1 -0.201 0.651  0.108  
ATOM   4842  N  N   . PHE B 1 245 ? -18.747 68.565  41.638  1    112.54 ? 234 PHE B N   1 -0.172 0.628  0.104  
ATOM   4843  C  CA  . PHE B 1 245 ? -18.371 67.324  40.963  1    107.91 ? 234 PHE B CA  1 -0.168 0.617  0.102  
ATOM   4844  C  C   . PHE B 1 245 ? -16.937 67.291  40.436  1    109.49 ? 234 PHE B C   1 -0.155 0.617  0.101  
ATOM   4845  O  O   . PHE B 1 245 ? -16.508 66.244  39.937  1    110.71 ? 234 PHE B O   1 -0.151 0.607  0.1    
ATOM   4846  C  CB  . PHE B 1 245 ? -19.325 67.049  39.791  1    105.41 ? 234 PHE B CB  1 -0.177 0.614  0.099  
ATOM   4847  C  CG  . PHE B 1 245 ? -20.765 66.861  40.193  1    105.2  ? 234 PHE B CG  1 -0.19  0.613  0.1    
ATOM   4848  C  CD1 . PHE B 1 245 ? -21.413 65.666  39.922  1    103.79 ? 234 PHE B CD1 1 -0.196 0.602  0.1    
ATOM   4849  C  CD2 . PHE B 1 245 ? -21.483 67.884  40.811  1    106.7  ? 234 PHE B CD2 1 -0.197 0.622  0.102  
ATOM   4850  C  CE1 . PHE B 1 245 ? -22.752 65.474  40.274  1    107.42 ? 234 PHE B CE1 1 -0.209 0.6    0.101  
ATOM   4851  C  CE2 . PHE B 1 245 ? -22.819 67.707  41.175  1    103.61 ? 234 PHE B CE2 1 -0.209 0.62   0.103  
ATOM   4852  C  CZ  . PHE B 1 245 ? -23.458 66.497  40.905  1    102.73 ? 234 PHE B CZ  1 -0.215 0.609  0.102  
ATOM   4853  N  N   . SER B 1 246 ? -16.176 68.383  40.557  1    111.62 ? 235 SER B N   1 -0.148 0.627  0.101  
ATOM   4854  C  CA  . SER B 1 246 ? -14.862 68.512  39.925  1    109.2  ? 235 SER B CA  1 -0.136 0.628  0.1    
ATOM   4855  C  C   . SER B 1 246 ? -13.871 67.41   40.294  1    108.43 ? 235 SER B C   1 -0.127 0.618  0.101  
ATOM   4856  O  O   . SER B 1 246 ? -12.768 67.388  39.742  1    111.53 ? 235 SER B O   1 -0.117 0.618  0.099  
ATOM   4857  C  CB  . SER B 1 246 ? -14.249 69.874  40.266  1    108.14 ? 235 SER B CB  1 -0.131 0.64   0.101  
ATOM   4858  O  OG  . SER B 1 246 ? -14.3   70.131  41.652  1    118.75 ? 235 SER B OG  1 -0.131 0.643  0.104  
ATOM   4859  N  N   . HIS B 1 247 ? -14.208 66.497  41.193  1    112.75 ? 236 HIS B N   1 -0.13  0.609  0.103  
ATOM   4860  C  CA  . HIS B 1 247 ? -13.262 65.439  41.509  1    115.94 ? 236 HIS B CA  1 -0.122 0.6    0.104  
ATOM   4861  C  C   . HIS B 1 247 ? -13.541 64.151  40.755  1    114.28 ? 236 HIS B C   1 -0.124 0.588  0.102  
ATOM   4862  O  O   . HIS B 1 247 ? -12.646 63.302  40.667  1    113.2  ? 236 HIS B O   1 -0.116 0.58   0.102  
ATOM   4863  C  CB  . HIS B 1 247 ? -13.229 65.161  43.022  1    119.65 ? 236 HIS B CB  1 -0.121 0.597  0.107  
ATOM   4864  C  CG  . HIS B 1 247 ? -12.293 66.06   43.787  1    126.45 ? 236 HIS B CG  1 -0.113 0.605  0.109  
ATOM   4865  N  ND1 . HIS B 1 247 ? -12.733 67.139  44.528  1    124.65 ? 236 HIS B ND1 1 -0.117 0.615  0.111  
ATOM   4866  C  CD2 . HIS B 1 247 ? -10.943 66.035  43.929  1    125.65 ? 236 HIS B CD2 1 -0.1   0.605  0.11   
ATOM   4867  C  CE1 . HIS B 1 247 ? -11.697 67.742  45.088  1    123.63 ? 236 HIS B CE1 1 -0.107 0.621  0.113  
ATOM   4868  N  NE2 . HIS B 1 247 ? -10.599 67.092  44.741  1    122.62 ? 236 HIS B NE2 1 -0.097 0.615  0.112  
ATOM   4869  N  N   . LEU B 1 248 ? -14.748 63.99   40.209  1    117.31 ? 237 LEU B N   1 -0.135 0.586  0.1    
ATOM   4870  C  CA  . LEU B 1 248 ? -15.02  62.958  39.21   1    117.37 ? 237 LEU B CA  1 -0.138 0.577  0.098  
ATOM   4871  C  C   . LEU B 1 248 ? -14.181 63.204  37.961  1    116.77 ? 237 LEU B C   1 -0.13  0.579  0.095  
ATOM   4872  O  O   . LEU B 1 248 ? -13.588 64.267  37.779  1    119.57 ? 237 LEU B O   1 -0.125 0.589  0.094  
ATOM   4873  C  CB  . LEU B 1 248 ? -16.503 62.938  38.836  1    111.52 ? 237 LEU B CB  1 -0.151 0.577  0.097  
ATOM   4874  C  CG  . LEU B 1 248 ? -17.419 62.612  40.017  1    117.03 ? 237 LEU B CG  1 -0.16  0.574  0.1    
ATOM   4875  C  CD1 . LEU B 1 248 ? -18.872 62.664  39.596  1    114.6  ? 237 LEU B CD1 1 -0.173 0.574  0.099  
ATOM   4876  C  CD2 . LEU B 1 248 ? -17.069 61.247  40.61   1    114.89 ? 237 LEU B CD2 1 -0.156 0.561  0.101  
ATOM   4877  N  N   . SER B 1 249 ? -14.127 62.217  37.082  1    114.74 ? 238 SER B N   1 -0.129 0.57   0.093  
ATOM   4878  C  CA  . SER B 1 249 ? -13.454 62.414  35.809  1    113.92 ? 238 SER B CA  1 -0.123 0.572  0.089  
ATOM   4879  C  C   . SER B 1 249 ? -14.52  62.733  34.768  1    111.51 ? 238 SER B C   1 -0.133 0.575  0.087  
ATOM   4880  O  O   . SER B 1 249 ? -15.387 61.898  34.485  1    110.02 ? 238 SER B O   1 -0.141 0.567  0.086  
ATOM   4881  C  CB  . SER B 1 249 ? -12.622 61.201  35.414  1    118.01 ? 238 SER B CB  1 -0.116 0.561  0.088  
ATOM   4882  O  OG  . SER B 1 249 ? -11.617 61.588  34.487  1    126.58 ? 238 SER B OG  1 -0.106 0.564  0.086  
ATOM   4883  N  N   . ILE B 1 250 ? -14.485 63.959  34.242  1    108.72 ? 239 ILE B N   1 -0.133 0.586  0.085  
ATOM   4884  C  CA  . ILE B 1 250 ? -15.483 64.437  33.294  1    112.55 ? 239 ILE B CA  1 -0.142 0.591  0.083  
ATOM   4885  C  C   . ILE B 1 250 ? -14.786 65.146  32.136  1    112.86 ? 239 ILE B C   1 -0.136 0.597  0.08   
ATOM   4886  O  O   . ILE B 1 250 ? -14.049 66.114  32.361  1    112    ? 239 ILE B O   1 -0.129 0.606  0.081  
ATOM   4887  C  CB  . ILE B 1 250 ? -16.484 65.392  33.964  1    110.53 ? 239 ILE B CB  1 -0.151 0.599  0.085  
ATOM   4888  C  CG1 . ILE B 1 250 ? -16.917 64.848  35.314  1    106    ? 239 ILE B CG1 1 -0.155 0.594  0.088  
ATOM   4889  C  CG2 . ILE B 1 250 ? -17.699 65.62   33.094  1    110.9  ? 239 ILE B CG2 1 -0.162 0.601  0.083  
ATOM   4890  C  CD1 . ILE B 1 250 ? -16.267 65.611  36.474  1    115.98 ? 239 ILE B CD1 1 -0.149 0.601  0.091  
ATOM   4891  N  N   . CYS B 1 251 ? -15.009 64.658  30.901  1    113.18 ? 240 CYS B N   1 -0.138 0.593  0.077  
ATOM   4892  C  CA  . CYS B 1 251 ? -14.816 65.446  29.681  1    108.77 ? 240 CYS B CA  1 -0.136 0.6    0.074  
ATOM   4893  C  C   . CYS B 1 251 ? -16.123 66.168  29.382  1    103.72 ? 240 CYS B C   1 -0.148 0.606  0.073  
ATOM   4894  O  O   . CYS B 1 251 ? -17.181 65.534  29.287  1    102.69 ? 240 CYS B O   1 -0.157 0.601  0.073  
ATOM   4895  C  CB  . CYS B 1 251 ? -14.427 64.575  28.483  1    113.4  ? 240 CYS B CB  1 -0.132 0.592  0.071  
ATOM   4896  S  SG  . CYS B 1 251 ? -12.649 64.29   28.228  1    142.03 ? 240 CYS B SG  1 -0.116 0.589  0.07   
ATOM   4897  N  N   . HIS B 1 252 ? -16.061 67.486  29.247  1    99.69  ? 241 HIS B N   1 -0.147 0.618  0.073  
ATOM   4898  C  CA  . HIS B 1 252 ? -17.254 68.279  28.96   1    101.21 ? 241 HIS B CA  1 -0.158 0.626  0.072  
ATOM   4899  C  C   . HIS B 1 252 ? -16.994 69.066  27.677  1    111.56 ? 241 HIS B C   1 -0.156 0.633  0.069  
ATOM   4900  O  O   . HIS B 1 252 ? -16.621 70.243  27.712  1    112.1  ? 241 HIS B O   1 -0.152 0.644  0.069  
ATOM   4901  C  CB  . HIS B 1 252 ? -17.578 69.162  30.098  1    104.34 ? 241 HIS B CB  1 -0.161 0.634  0.075  
ATOM   4902  C  CG  . HIS B 1 252 ? -18.894 69.856  29.963  1    107.19 ? 241 HIS B CG  1 -0.173 0.64   0.075  
ATOM   4903  N  ND1 . HIS B 1 252 ? -19.738 69.643  28.894  1    105.28 ? 241 HIS B ND1 1 -0.181 0.638  0.072  
ATOM   4904  C  CD2 . HIS B 1 252 ? -19.512 70.762  30.759  1    109.49 ? 241 HIS B CD2 1 -0.179 0.648  0.077  
ATOM   4905  C  CE1 . HIS B 1 252 ? -20.816 70.396  29.032  1    106.47 ? 241 HIS B CE1 1 -0.191 0.645  0.072  
ATOM   4906  N  NE2 . HIS B 1 252 ? -20.706 71.082  30.158  1    111.41 ? 241 HIS B NE2 1 -0.19  0.651  0.075  
ATOM   4907  N  N   . ILE B 1 253 ? -17.163 68.396  26.536  1    111    ? 242 ILE B N   1 -0.157 0.627  0.066  
ATOM   4908  C  CA  . ILE B 1 253 ? -17.179 69.066  25.236  1    108.01 ? 242 ILE B CA  1 -0.157 0.633  0.063  
ATOM   4909  C  C   . ILE B 1 253 ? -18.483 69.859  25.151  1    104.08 ? 242 ILE B C   1 -0.169 0.64   0.063  
ATOM   4910  O  O   . ILE B 1 253 ? -19.572 69.28   25.049  1    97.68  ? 242 ILE B O   1 -0.179 0.635  0.063  
ATOM   4911  C  CB  . ILE B 1 253 ? -17.053 68.068  24.075  1    105.26 ? 242 ILE B CB  1 -0.156 0.624  0.06   
ATOM   4912  C  CG1 . ILE B 1 253 ? -15.662 67.427  24.019  1    107.06 ? 242 ILE B CG1 1 -0.144 0.618  0.06   
ATOM   4913  C  CG2 . ILE B 1 253 ? -17.324 68.745  22.774  1    103.19 ? 242 ILE B CG2 1 -0.159 0.63   0.057  
ATOM   4914  C  CD1 . ILE B 1 253 ? -15.494 66.224  24.943  1    109.79 ? 242 ILE B CD1 1 -0.142 0.607  0.062  
ATOM   4915  N  N   . ASP B 1 254 ? -18.381 71.185  25.223  1    101.8  ? 243 ASP B N   1 -0.168 0.652  0.063  
ATOM   4916  C  CA  . ASP B 1 254 ? -19.544 72.061  25.142  1    105.55 ? 243 ASP B CA  1 -0.179 0.66   0.063  
ATOM   4917  C  C   . ASP B 1 254 ? -19.487 72.831  23.819  1    105.84 ? 243 ASP B C   1 -0.179 0.667  0.059  
ATOM   4918  O  O   . ASP B 1 254 ? -18.661 73.733  23.648  1    104.77 ? 243 ASP B O   1 -0.171 0.676  0.059  
ATOM   4919  C  CB  . ASP B 1 254 ? -19.607 73.01   26.337  1    98.86  ? 243 ASP B CB  1 -0.18  0.669  0.066  
ATOM   4920  C  CG  . ASP B 1 254 ? -20.919 73.779  26.388  1    101.75 ? 243 ASP B CG  1 -0.192 0.676  0.066  
ATOM   4921  O  OD1 . ASP B 1 254 ? -21.777 73.575  25.486  1    105.22 ? 243 ASP B OD1 1 -0.2   0.674  0.064  
ATOM   4922  O  OD2 . ASP B 1 254 ? -21.098 74.589  27.323  1    96.52  ? 243 ASP B OD2 1 -0.193 0.684  0.068  
ATOM   4923  N  N   . VAL B 1 255 ? -20.356 72.464  22.884  1    105.11 ? 244 VAL B N   1 -0.187 0.664  0.057  
ATOM   4924  C  CA  . VAL B 1 255 ? -20.483 73.17   21.613  1    105.52 ? 244 VAL B CA  1 -0.188 0.671  0.054  
ATOM   4925  C  C   . VAL B 1 255 ? -21.471 74.317  21.801  1    105.99 ? 244 VAL B C   1 -0.197 0.681  0.054  
ATOM   4926  O  O   . VAL B 1 255 ? -22.563 74.115  22.351  1    108.9  ? 244 VAL B O   1 -0.207 0.679  0.056  
ATOM   4927  C  CB  . VAL B 1 255 ? -20.954 72.213  20.503  1    106.14 ? 244 VAL B CB  1 -0.192 0.662  0.051  
ATOM   4928  C  CG1 . VAL B 1 255 ? -20.744 72.832  19.118  1    105.35 ? 244 VAL B CG1 1 -0.19  0.667  0.048  
ATOM   4929  C  CG2 . VAL B 1 255 ? -20.247 70.865  20.615  1    104    ? 244 VAL B CG2 1 -0.186 0.649  0.051  
ATOM   4930  N  N   . PHE B 1 256 ? -21.102 75.52   21.351  1    97.83  ? 245 PHE B N   1 -0.193 0.692  0.053  
ATOM   4931  C  CA  . PHE B 1 256 ? -22.05  76.63   21.403  1    96.42  ? 245 PHE B CA  1 -0.202 0.702  0.053  
ATOM   4932  C  C   . PHE B 1 256 ? -21.524 77.819  20.601  1    98.03  ? 245 PHE B C   1 -0.197 0.713  0.051  
ATOM   4933  O  O   . PHE B 1 256 ? -20.334 77.914  20.285  1    94.38  ? 245 PHE B O   1 -0.186 0.714  0.051  
ATOM   4934  C  CB  . PHE B 1 256 ? -22.331 77.054  22.849  1    99.46  ? 245 PHE B CB  1 -0.205 0.706  0.057  
ATOM   4935  C  CG  . PHE B 1 256 ? -21.2   77.8    23.484  1    98.06  ? 245 PHE B CG  1 -0.194 0.713  0.059  
ATOM   4936  C  CD1 . PHE B 1 256 ? -20.198 77.126  24.173  1    96.66  ? 245 PHE B CD1 1 -0.185 0.707  0.06   
ATOM   4937  C  CD2 . PHE B 1 256 ? -21.134 79.18   23.386  1    97.41  ? 245 PHE B CD2 1 -0.194 0.726  0.058  
ATOM   4938  C  CE1 . PHE B 1 256 ? -19.151 77.82   24.75   1    96.37  ? 245 PHE B CE1 1 -0.176 0.713  0.062  
ATOM   4939  C  CE2 . PHE B 1 256 ? -20.092 79.88   23.948  1    100.01 ? 245 PHE B CE2 1 -0.184 0.732  0.06   
ATOM   4940  C  CZ  . PHE B 1 256 ? -19.1   79.203  24.638  1    103.18 ? 245 PHE B CZ  1 -0.175 0.726  0.062  
ATOM   4941  N  N   . ASP B 1 257 ? -22.435 78.743  20.304  1    96.49  ? 246 ASP B N   1 -0.206 0.722  0.051  
ATOM   4942  C  CA  . ASP B 1 257 ? -22.105 80.007  19.66   1    97.81  ? 246 ASP B CA  1 -0.203 0.733  0.049  
ATOM   4943  C  C   . ASP B 1 257 ? -22.03  81.107  20.716  1    102.3  ? 246 ASP B C   1 -0.202 0.743  0.052  
ATOM   4944  O  O   . ASP B 1 257 ? -23.023 81.392  21.398  1    95.55  ? 246 ASP B O   1 -0.211 0.746  0.053  
ATOM   4945  C  CB  . ASP B 1 257 ? -23.148 80.363  18.6    1    102.27 ? 246 ASP B CB  1 -0.212 0.736  0.046  
ATOM   4946  C  CG  . ASP B 1 257 ? -22.721 81.532  17.723  1    103.72 ? 246 ASP B CG  1 -0.208 0.747  0.044  
ATOM   4947  O  OD1 . ASP B 1 257 ? -21.773 82.261  18.12   1    97.36  ? 246 ASP B OD1 1 -0.2   0.754  0.045  
ATOM   4948  O  OD2 . ASP B 1 257 ? -23.335 81.713  16.634  1    105.64 ? 246 ASP B OD2 1 -0.214 0.749  0.042  
ATOM   4949  N  N   . SER B 1 258 ? -20.875 81.765  20.797  1    104.98 ? 247 SER B N   1 -0.191 0.749  0.052  
ATOM   4950  C  CA  . SER B 1 258 ? -20.623 82.785  21.807  1    102.73 ? 247 SER B CA  1 -0.189 0.759  0.054  
ATOM   4951  C  C   . SER B 1 258 ? -21.33  84.108  21.545  1    108.03 ? 247 SER B C   1 -0.195 0.771  0.054  
ATOM   4952  O  O   . SER B 1 258 ? -21.198 85.018  22.372  1    111.78 ? 247 SER B O   1 -0.194 0.779  0.056  
ATOM   4953  C  CB  . SER B 1 258 ? -19.121 83.061  21.927  1    103.35 ? 247 SER B CB  1 -0.175 0.761  0.055  
ATOM   4954  O  OG  . SER B 1 258 ? -18.672 83.875  20.851  1    101.11 ? 247 SER B OG  1 -0.171 0.769  0.052  
ATOM   4955  N  N   . ARG B 1 259 ? -22.049 84.272  20.436  1    106.98 ? 248 ARG B N   1 -0.202 0.772  0.051  
ATOM   4956  C  CA  . ARG B 1 259 ? -22.706 85.543  20.166  1    105.66 ? 248 ARG B CA  1 -0.208 0.784  0.05   
ATOM   4957  C  C   . ARG B 1 259 ? -24.215 85.482  20.322  1    108.55 ? 248 ARG B C   1 -0.222 0.783  0.051  
ATOM   4958  O  O   . ARG B 1 259 ? -24.901 86.448  19.972  1    113.83 ? 248 ARG B O   1 -0.228 0.792  0.05   
ATOM   4959  C  CB  . ARG B 1 259 ? -22.364 86.045  18.772  1    108.37 ? 248 ARG B CB  1 -0.205 0.789  0.047  
ATOM   4960  C  CG  . ARG B 1 259 ? -20.938 86.489  18.598  1    114.17 ? 248 ARG B CG  1 -0.192 0.793  0.046  
ATOM   4961  C  CD  . ARG B 1 259 ? -20.084 85.357  18.086  1    113.14 ? 248 ARG B CD  1 -0.184 0.782  0.045  
ATOM   4962  N  NE  . ARG B 1 259 ? -20.818 84.458  17.202  1    115.5  ? 248 ARG B NE  1 -0.191 0.774  0.043  
ATOM   4963  C  CZ  . ARG B 1 259 ? -21.021 84.668  15.908  1    110.16 ? 248 ARG B CZ  1 -0.193 0.776  0.04   
ATOM   4964  N  NH1 . ARG B 1 259 ? -20.68  85.809  15.339  1    116.18 ? 248 ARG B NH1 1 -0.19  0.786  0.038  
ATOM   4965  N  NH2 . ARG B 1 259 ? -21.564 83.702  15.168  1    100.54 ? 248 ARG B NH2 1 -0.198 0.767  0.038  
ATOM   4966  N  N   . VAL B 1 260 ? -24.755 84.375  20.817  1    106.45 ? 249 VAL B N   1 -0.227 0.773  0.052  
ATOM   4967  C  CA  . VAL B 1 260 ? -26.149 84.361  21.242  1    113.48 ? 249 VAL B CA  1 -0.24  0.773  0.053  
ATOM   4968  C  C   . VAL B 1 260 ? -26.154 84.188  22.75   1    111.81 ? 249 VAL B C   1 -0.24  0.772  0.057  
ATOM   4969  O  O   . VAL B 1 260 ? -25.092 84.211  23.383  1    110.99 ? 249 VAL B O   1 -0.23  0.772  0.058  
ATOM   4970  C  CB  . VAL B 1 260 ? -26.951 83.256  20.542  1    110.56 ? 249 VAL B CB  1 -0.247 0.763  0.051  
ATOM   4971  C  CG1 . VAL B 1 260 ? -27.37  83.741  19.19   1    114.94 ? 249 VAL B CG1 1 -0.251 0.767  0.048  
ATOM   4972  C  CG2 . VAL B 1 260 ? -26.115 81.971  20.443  1    105    ? 249 VAL B CG2 1 -0.239 0.751  0.051  
ATOM   4973  N  N   . TYR B 1 261 ? -27.329 84.03   23.333  1    110.31 ? 250 TYR B N   1 -0.25  0.77   0.058  
ATOM   4974  C  CA  . TYR B 1 261 ? -27.407 83.767  24.76   1    113.85 ? 250 TYR B CA  1 -0.251 0.768  0.062  
ATOM   4975  C  C   . TYR B 1 261 ? -26.506 82.581  25.116  1    112.43 ? 250 TYR B C   1 -0.243 0.757  0.063  
ATOM   4976  O  O   . TYR B 1 261 ? -26.379 81.634  24.326  1    111.19 ? 250 TYR B O   1 -0.242 0.748  0.061  
ATOM   4977  C  CB  . TYR B 1 261 ? -28.86  83.486  25.148  1    116.07 ? 250 TYR B CB  1 -0.264 0.765  0.063  
ATOM   4978  C  CG  . TYR B 1 261 ? -29.133 83.325  26.618  1    113.57 ? 250 TYR B CG  1 -0.267 0.764  0.066  
ATOM   4979  C  CD1 . TYR B 1 261 ? -28.811 82.145  27.282  1    109.16 ? 250 TYR B CD1 1 -0.264 0.753  0.068  
ATOM   4980  C  CD2 . TYR B 1 261 ? -29.761 84.334  27.337  1    116.73 ? 250 TYR B CD2 1 -0.273 0.773  0.068  
ATOM   4981  C  CE1 . TYR B 1 261 ? -29.075 81.991  28.631  1    113.98 ? 250 TYR B CE1 1 -0.266 0.751  0.071  
ATOM   4982  C  CE2 . TYR B 1 261 ? -30.035 84.188  28.691  1    117.16 ? 250 TYR B CE2 1 -0.275 0.772  0.072  
ATOM   4983  C  CZ  . TYR B 1 261 ? -29.692 83.014  29.334  1    114.59 ? 250 TYR B CZ  1 -0.272 0.761  0.073  
ATOM   4984  O  OH  . TYR B 1 261 ? -29.967 82.851  30.674  1    110.31 ? 250 TYR B OH  1 -0.275 0.759  0.077  
ATOM   4985  N  N   . PRO B 1 262 ? -25.811 82.628  26.251  1    107.86 ? 251 PRO B N   1 -0.237 0.757  0.066  
ATOM   4986  C  CA  . PRO B 1 262 ? -25.69  83.758  27.183  1    109.09 ? 251 PRO B CA  1 -0.235 0.768  0.068  
ATOM   4987  C  C   . PRO B 1 262 ? -24.506 84.68   26.895  1    108.27 ? 251 PRO B C   1 -0.225 0.776  0.067  
ATOM   4988  O  O   . PRO B 1 262 ? -24.014 85.311  27.815  1    108.67 ? 251 PRO B O   1 -0.22  0.782  0.069  
ATOM   4989  C  CB  . PRO B 1 262 ? -25.516 83.052  28.533  1    108.16 ? 251 PRO B CB  1 -0.234 0.761  0.071  
ATOM   4990  C  CG  . PRO B 1 262 ? -24.703 81.838  28.191  1    107.03 ? 251 PRO B CG  1 -0.226 0.75   0.07   
ATOM   4991  C  CD  . PRO B 1 262 ? -25.194 81.41   26.802  1    111.45 ? 251 PRO B CD  1 -0.231 0.746  0.067  
ATOM   4992  N  N   . GLN B 1 263 ? -23.992 84.783  25.663  1    114.24 ? 252 GLN B N   1 -0.22  0.777  0.064  
ATOM   4993  C  CA  . GLN B 1 263 ? -23.015 85.807  25.272  1    109.2  ? 252 GLN B CA  1 -0.211 0.786  0.063  
ATOM   4994  C  C   . GLN B 1 263 ? -21.652 85.635  25.942  1    103.83 ? 252 GLN B C   1 -0.198 0.785  0.065  
ATOM   4995  O  O   . GLN B 1 263 ? -20.855 86.581  25.985  1    94.18  ? 252 GLN B O   1 -0.191 0.793  0.065  
ATOM   4996  C  CB  . GLN B 1 263 ? -23.554 87.21   25.557  1    106.78 ? 252 GLN B CB  1 -0.216 0.799  0.064  
ATOM   4997  C  CG  . GLN B 1 263 ? -24.967 87.433  25.046  1    110.27 ? 252 GLN B CG  1 -0.229 0.801  0.063  
ATOM   4998  C  CD  . GLN B 1 263 ? -24.957 87.852  23.619  1    112.43 ? 252 GLN B CD  1 -0.229 0.805  0.059  
ATOM   4999  O  OE1 . GLN B 1 263 ? -24.015 88.509  23.179  1    111.14 ? 252 GLN B OE1 1 -0.22  0.811  0.058  
ATOM   5000  N  NE2 . GLN B 1 263 ? -25.987 87.464  22.866  1    118.98 ? 252 GLN B NE2 1 -0.238 0.802  0.057  
ATOM   5001  N  N   . GLN B 1 264 ? -21.328 84.44   26.413  1    97.7   ? 253 GLN B N   1 -0.195 0.774  0.066  
ATOM   5002  C  CA  . GLN B 1 264 ? -20.136 84.224  27.216  1    100.12 ? 253 GLN B CA  1 -0.185 0.772  0.068  
ATOM   5003  C  C   . GLN B 1 264 ? -19.053 83.558  26.378  1    97.94  ? 253 GLN B C   1 -0.175 0.766  0.066  
ATOM   5004  O  O   . GLN B 1 264 ? -19.233 82.421  25.924  1    99.46  ? 253 GLN B O   1 -0.176 0.755  0.065  
ATOM   5005  C  CB  . GLN B 1 264 ? -20.487 83.367  28.433  1    111.87 ? 253 GLN B CB  1 -0.188 0.764  0.071  
ATOM   5006  C  CG  . GLN B 1 264 ? -21.562 83.979  29.328  1    108.53 ? 253 GLN B CG  1 -0.198 0.77   0.073  
ATOM   5007  C  CD  . GLN B 1 264 ? -22.137 82.978  30.303  1    108.66 ? 253 GLN B CD  1 -0.203 0.76   0.076  
ATOM   5008  O  OE1 . GLN B 1 264 ? -21.633 81.859  30.423  1    108.1  ? 253 GLN B OE1 1 -0.198 0.75   0.076  
ATOM   5009  N  NE2 . GLN B 1 264 ? -23.191 83.375  31.014  1    109.27 ? 253 GLN B NE2 1 -0.213 0.764  0.077  
ATOM   5010  N  N   . ASP B 1 265 ? -17.917 84.247  26.205  1    99.39  ? 254 ASP B N   1 -0.164 0.772  0.065  
ATOM   5011  C  CA  . ASP B 1 265 ? -16.837 83.763  25.341  1    104.14 ? 254 ASP B CA  1 -0.154 0.768  0.063  
ATOM   5012  C  C   . ASP B 1 265 ? -15.726 83.092  26.159  1    106.13 ? 254 ASP B C   1 -0.144 0.761  0.065  
ATOM   5013  O  O   . ASP B 1 265 ? -15.93  82.713  27.321  1    111.88 ? 254 ASP B O   1 -0.146 0.758  0.068  
ATOM   5014  C  CB  . ASP B 1 265 ? -16.305 84.911  24.464  1    104.76 ? 254 ASP B CB  1 -0.149 0.778  0.061  
ATOM   5015  C  CG  . ASP B 1 265 ? -15.44  85.927  25.219  1    106.86 ? 254 ASP B CG  1 -0.141 0.787  0.063  
ATOM   5016  O  OD1 . ASP B 1 265 ? -15.032 85.71   26.375  1    110.19 ? 254 ASP B OD1 1 -0.138 0.785  0.066  
ATOM   5017  O  OD2 . ASP B 1 265 ? -15.157 86.983  24.624  1    113.57 ? 254 ASP B OD2 1 -0.139 0.797  0.061  
ATOM   5018  N  N   . PHE B 1 266 ? -14.533 82.962  25.562  1    104.22 ? 255 PHE B N   1 -0.133 0.76   0.064  
ATOM   5019  C  CA  . PHE B 1 266 ? -13.439 82.272  26.245  1    106.7  ? 255 PHE B CA  1 -0.123 0.754  0.066  
ATOM   5020  C  C   . PHE B 1 266 ? -12.923 83.084  27.426  1    106.25 ? 255 PHE B C   1 -0.118 0.761  0.068  
ATOM   5021  O  O   . PHE B 1 266 ? -12.672 82.53   28.498  1    111.43 ? 255 PHE B O   1 -0.116 0.756  0.071  
ATOM   5022  C  CB  . PHE B 1 266 ? -12.292 81.962  25.278  1    109.06 ? 255 PHE B CB  1 -0.113 0.751  0.063  
ATOM   5023  C  CG  . PHE B 1 266 ? -12.613 80.899  24.254  1    110.52 ? 255 PHE B CG  1 -0.116 0.741  0.061  
ATOM   5024  C  CD1 . PHE B 1 266 ? -13.786 80.167  24.326  1    108.98 ? 255 PHE B CD1 1 -0.126 0.735  0.061  
ATOM   5025  C  CD2 . PHE B 1 266 ? -11.728 80.637  23.218  1    116.43 ? 255 PHE B CD2 1 -0.107 0.739  0.058  
ATOM   5026  C  CE1 . PHE B 1 266 ? -14.076 79.194  23.389  1    111.31 ? 255 PHE B CE1 1 -0.129 0.726  0.058  
ATOM   5027  C  CE2 . PHE B 1 266 ? -12.006 79.669  22.271  1    119.43 ? 255 PHE B CE2 1 -0.11  0.73   0.056  
ATOM   5028  C  CZ  . PHE B 1 266 ? -13.183 78.944  22.356  1    120.86 ? 255 PHE B CZ  1 -0.121 0.723  0.056  
ATOM   5029  N  N   . ALA B 1 267 ? -12.753 84.396  27.25   1    106.11 ? 256 ALA B N   1 -0.117 0.773  0.068  
ATOM   5030  C  CA  . ALA B 1 267 ? -12.374 85.248  28.372  1    99.58  ? 256 ALA B CA  1 -0.113 0.781  0.071  
ATOM   5031  C  C   . ALA B 1 267 ? -13.386 85.155  29.507  1    106.73 ? 256 ALA B C   1 -0.123 0.78   0.074  
ATOM   5032  O  O   . ALA B 1 267 ? -13.005 85.099  30.686  1    114.41 ? 256 ALA B O   1 -0.119 0.78   0.077  
ATOM   5033  C  CB  . ALA B 1 267 ? -12.229 86.7    27.919  1    96.66  ? 256 ALA B CB  1 -0.112 0.795  0.07   
ATOM   5034  N  N   . TYR B 1 268 ? -14.682 85.153  29.179  1    102.01 ? 257 TYR B N   1 -0.135 0.78   0.073  
ATOM   5035  C  CA  . TYR B 1 268 ? -15.684 85.056  30.231  1    108.11 ? 257 TYR B CA  1 -0.144 0.779  0.075  
ATOM   5036  C  C   . TYR B 1 268 ? -15.499 83.771  31.025  1    114.12 ? 257 TYR B C   1 -0.142 0.768  0.077  
ATOM   5037  O  O   . TYR B 1 268 ? -15.609 83.768  32.26   1    111.47 ? 257 TYR B O   1 -0.143 0.768  0.081  
ATOM   5038  C  CB  . TYR B 1 268 ? -17.098 85.134  29.654  1    103.99 ? 257 TYR B CB  1 -0.157 0.78   0.074  
ATOM   5039  C  CG  . TYR B 1 268 ? -18.167 84.994  30.716  1    109.21 ? 257 TYR B CG  1 -0.166 0.779  0.077  
ATOM   5040  C  CD1 . TYR B 1 268 ? -18.616 83.74   31.111  1    112.46 ? 257 TYR B CD1 1 -0.171 0.767  0.078  
ATOM   5041  C  CD2 . TYR B 1 268 ? -18.705 86.112  31.347  1    109.62 ? 257 TYR B CD2 1 -0.171 0.789  0.078  
ATOM   5042  C  CE1 . TYR B 1 268 ? -19.568 83.599  32.093  1    115.39 ? 257 TYR B CE1 1 -0.179 0.766  0.08   
ATOM   5043  C  CE2 . TYR B 1 268 ? -19.673 85.982  32.33   1    108.27 ? 257 TYR B CE2 1 -0.18  0.788  0.081  
ATOM   5044  C  CZ  . TYR B 1 268 ? -20.103 84.717  32.695  1    113.71 ? 257 TYR B CZ  1 -0.184 0.776  0.082  
ATOM   5045  O  OH  . TYR B 1 268 ? -21.068 84.551  33.667  1    114.15 ? 257 TYR B OH  1 -0.193 0.775  0.084  
ATOM   5046  N  N   . ILE B 1 269 ? -15.211 82.671  30.331  1    110.96 ? 258 ILE B N   1 -0.139 0.758  0.076  
ATOM   5047  C  CA  . ILE B 1 269 ? -14.943 81.415  31.013  1    107.59 ? 258 ILE B CA  1 -0.137 0.746  0.077  
ATOM   5048  C  C   . ILE B 1 269 ? -13.658 81.501  31.818  1    109.04 ? 258 ILE B C   1 -0.125 0.747  0.079  
ATOM   5049  O  O   . ILE B 1 269 ? -13.521 80.828  32.843  1    116.92 ? 258 ILE B O   1 -0.124 0.741  0.082  
ATOM   5050  C  CB  . ILE B 1 269 ? -14.912 80.269  29.989  1    109.41 ? 258 ILE B CB  1 -0.137 0.736  0.075  
ATOM   5051  C  CG1 . ILE B 1 269 ? -16.286 80.145  29.314  1    104.33 ? 258 ILE B CG1 1 -0.149 0.734  0.073  
ATOM   5052  C  CG2 . ILE B 1 269 ? -14.492 78.955  30.641  1    106.12 ? 258 ILE B CG2 1 -0.133 0.724  0.077  
ATOM   5053  C  CD1 . ILE B 1 269 ? -16.259 79.353  28.03   1    104.76 ? 258 ILE B CD1 1 -0.149 0.727  0.07   
ATOM   5054  N  N   . ASN B 1 270 ? -12.712 82.349  31.405  1    107.07 ? 259 ASN B N   1 -0.116 0.755  0.078  
ATOM   5055  C  CA  . ASN B 1 270 ? -11.438 82.42   32.114  1    109.2  ? 259 ASN B CA  1 -0.105 0.755  0.08   
ATOM   5056  C  C   . ASN B 1 270 ? -11.624 82.89   33.55   1    115.19 ? 259 ASN B C   1 -0.107 0.76   0.084  
ATOM   5057  O  O   . ASN B 1 270 ? -11.356 82.145  34.501  1    112.65 ? 259 ASN B O   1 -0.104 0.753  0.086  
ATOM   5058  C  CB  . ASN B 1 270 ? -10.462 83.327  31.373  1    108.47 ? 259 ASN B CB  1 -0.096 0.764  0.078  
ATOM   5059  C  CG  . ASN B 1 270 ? -9.624  82.56   30.377  1    118.64 ? 259 ASN B CG  1 -0.088 0.757  0.076  
ATOM   5060  O  OD1 . ASN B 1 270 ? -9.659  81.328  30.355  1    119.75 ? 259 ASN B OD1 1 -0.089 0.745  0.076  
ATOM   5061  N  ND2 . ASN B 1 270 ? -8.858  83.276  29.55   1    114.06 ? 259 ASN B ND2 1 -0.081 0.763  0.074  
ATOM   5062  N  N   . ASN B 1 271 ? -12.09  84.124  33.734  1    115.05 ? 260 ASN B N   1 -0.111 0.771  0.084  
ATOM   5063  C  CA  . ASN B 1 271 ? -12.196 84.631  35.096  1    114.68 ? 260 ASN B CA  1 -0.112 0.776  0.088  
ATOM   5064  C  C   . ASN B 1 271 ? -13.359 83.998  35.861  1    117.02 ? 260 ASN B C   1 -0.122 0.77   0.09   
ATOM   5065  O  O   . ASN B 1 271 ? -13.618 84.391  37.016  1    119.22 ? 260 ASN B O   1 -0.125 0.773  0.092  
ATOM   5066  C  CB  . ASN B 1 271 ? -12.286 86.162  35.077  1    109.93 ? 260 ASN B CB  1 -0.113 0.79   0.088  
ATOM   5067  C  CG  . ASN B 1 271 ? -13.706 86.67   35.073  1    119.46 ? 260 ASN B CG  1 -0.126 0.794  0.088  
ATOM   5068  O  OD1 . ASN B 1 271 ? -14.604 86.066  34.477  1    123.7  ? 260 ASN B OD1 1 -0.134 0.789  0.086  
ATOM   5069  N  ND2 . ASN B 1 271 ? -13.92  87.802  35.73   1    118.74 ? 260 ASN B ND2 1 -0.128 0.805  0.089  
ATOM   5070  N  N   . GLU B 1 272 ? -14.042 83.025  35.248  1    108.02 ? 261 GLU B N   1 -0.129 0.761  0.088  
ATOM   5071  C  CA  . GLU B 1 272 ? -14.977 82.143  35.932  1    111.45 ? 261 GLU B CA  1 -0.137 0.753  0.09   
ATOM   5072  C  C   . GLU B 1 272 ? -14.266 80.937  36.564  1    115.65 ? 261 GLU B C   1 -0.131 0.742  0.091  
ATOM   5073  O  O   . GLU B 1 272 ? -14.532 80.586  37.723  1    113.78 ? 261 GLU B O   1 -0.133 0.739  0.094  
ATOM   5074  C  CB  . GLU B 1 272 ? -16.081 81.718  34.957  1    108.27 ? 261 GLU B CB  1 -0.147 0.749  0.087  
ATOM   5075  C  CG  . GLU B 1 272 ? -16.295 80.227  34.789  1    111.49 ? 261 GLU B CG  1 -0.149 0.735  0.087  
ATOM   5076  C  CD  . GLU B 1 272 ? -17.717 79.891  34.36   1    114.89 ? 261 GLU B CD  1 -0.162 0.732  0.086  
ATOM   5077  O  OE1 . GLU B 1 272 ? -18.435 80.807  33.892  1    109.35 ? 261 GLU B OE1 1 -0.169 0.741  0.085  
ATOM   5078  O  OE2 . GLU B 1 272 ? -18.125 78.715  34.518  1    120.28 ? 261 GLU B OE2 1 -0.166 0.721  0.086  
ATOM   5079  N  N   . PHE B 1 273 ? -13.35  80.304  35.827  1    115.17 ? 262 PHE B N   1 -0.122 0.736  0.089  
ATOM   5080  C  CA  . PHE B 1 273 ? -12.443 79.306  36.39   1    116.89 ? 262 PHE B CA  1 -0.114 0.727  0.091  
ATOM   5081  C  C   . PHE B 1 273 ? -11.295 79.932  37.171  1    116.62 ? 262 PHE B C   1 -0.104 0.733  0.093  
ATOM   5082  O  O   . PHE B 1 273 ? -10.451 79.194  37.699  1    110.13 ? 262 PHE B O   1 -0.096 0.726  0.094  
ATOM   5083  C  CB  . PHE B 1 273 ? -11.85  78.43   35.278  1    113.44 ? 262 PHE B CB  1 -0.109 0.719  0.088  
ATOM   5084  C  CG  . PHE B 1 273 ? -12.772 77.358  34.773  1    112.89 ? 262 PHE B CG  1 -0.117 0.709  0.087  
ATOM   5085  C  CD1 . PHE B 1 273 ? -13.784 77.661  33.876  1    116.46 ? 262 PHE B CD1 1 -0.126 0.712  0.085  
ATOM   5086  C  CD2 . PHE B 1 273 ? -12.602 76.038  35.158  1    109.94 ? 262 PHE B CD2 1 -0.115 0.697  0.088  
ATOM   5087  C  CE1 . PHE B 1 273 ? -14.626 76.669  33.386  1    115.6  ? 262 PHE B CE1 1 -0.134 0.703  0.083  
ATOM   5088  C  CE2 . PHE B 1 273 ? -13.444 75.04   34.671  1    113.44 ? 262 PHE B CE2 1 -0.123 0.688  0.087  
ATOM   5089  C  CZ  . PHE B 1 273 ? -14.457 75.359  33.782  1    113.49 ? 262 PHE B CZ  1 -0.132 0.691  0.084  
ATOM   5090  N  N   . ASN B 1 274 ? -11.258 81.267  37.251  1    119.16 ? 263 ASN B N   1 -0.103 0.745  0.093  
ATOM   5091  C  CA  . ASN B 1 274 ? -10.077 82.041  37.623  1    117.87 ? 263 ASN B CA  1 -0.092 0.752  0.094  
ATOM   5092  C  C   . ASN B 1 274 ? -8.813  81.334  37.132  1    117.52 ? 263 ASN B C   1 -0.081 0.745  0.093  
ATOM   5093  O  O   . ASN B 1 274 ? -7.894  81.046  37.908  1    112.7  ? 263 ASN B O   1 -0.072 0.743  0.095  
ATOM   5094  C  CB  . ASN B 1 274 ? -10.084 82.317  39.128  1    112.38 ? 263 ASN B CB  1 -0.092 0.754  0.098  
ATOM   5095  C  CG  . ASN B 1 274 ? -11.111 83.391  39.512  1    119.46 ? 263 ASN B CG  1 -0.102 0.764  0.099  
ATOM   5096  O  OD1 . ASN B 1 274 ? -11.434 84.284  38.706  1    110.99 ? 263 ASN B OD1 1 -0.105 0.772  0.097  
ATOM   5097  N  ND2 . ASN B 1 274 ? -11.625 83.313  40.742  1    119.4  ? 263 ASN B ND2 1 -0.107 0.763  0.102  
ATOM   5098  N  N   . SER B 1 275 ? -8.785  81.05   35.825  1    116.52 ? 264 SER B N   1 -0.081 0.743  0.089  
ATOM   5099  C  CA  . SER B 1 275 ? -7.681  80.391  35.131  1    120.52 ? 264 SER B CA  1 -0.07  0.737  0.088  
ATOM   5100  C  C   . SER B 1 275 ? -7.892  80.501  33.622  1    123.06 ? 264 SER B C   1 -0.072 0.738  0.084  
ATOM   5101  O  O   . SER B 1 275 ? -9.009  80.728  33.149  1    123.62 ? 264 SER B O   1 -0.083 0.74   0.083  
ATOM   5102  C  CB  . SER B 1 275 ? -7.555  78.925  35.535  1    121.51 ? 264 SER B CB  1 -0.069 0.723  0.089  
ATOM   5103  O  OG  . SER B 1 275 ? -6.593  78.287  34.715  1    119.86 ? 264 SER B OG  1 -0.06  0.717  0.087  
ATOM   5104  N  N   . GLU B 1 276 ? -6.809  80.308  32.869  1    123.3  ? 265 GLU B N   1 -0.062 0.736  0.082  
ATOM   5105  C  CA  . GLU B 1 276 ? -6.788  80.59   31.435  1    124.62 ? 265 GLU B CA  1 -0.062 0.739  0.078  
ATOM   5106  C  C   . GLU B 1 276 ? -6.645  79.294  30.648  1    123.46 ? 265 GLU B C   1 -0.061 0.727  0.077  
ATOM   5107  O  O   . GLU B 1 276 ? -5.617  78.618  30.745  1    122.54 ? 265 GLU B O   1 -0.051 0.72   0.077  
ATOM   5108  C  CB  . GLU B 1 276 ? -5.649  81.548  31.092  1    128.14 ? 265 GLU B CB  1 -0.052 0.747  0.078  
ATOM   5109  C  CG  . GLU B 1 276 ? -5.333  82.506  32.233  1    139.68 ? 265 GLU B CG  1 -0.049 0.756  0.08   
ATOM   5110  C  CD  . GLU B 1 276 ? -4.33   83.591  31.857  1    154.38 ? 265 GLU B CD  1 -0.04  0.766  0.08   
ATOM   5111  O  OE1 . GLU B 1 276 ? -3.798  84.246  32.798  1    152.44 ? 265 GLU B OE1 1 -0.035 0.772  0.082  
ATOM   5112  O  OE2 . GLU B 1 276 ? -4.082  83.789  30.639  1    145.19 ? 265 GLU B OE2 1 -0.037 0.768  0.076  
ATOM   5113  N  N   . GLY B 1 277 ? -7.656  78.975  29.838  1    124.64 ? 266 GLY B N   1 -0.07  0.724  0.074  
ATOM   5114  C  CA  . GLY B 1 277 ? -7.643  77.724  29.092  1    125.61 ? 266 GLY B CA  1 -0.07  0.712  0.073  
ATOM   5115  C  C   . GLY B 1 277 ? -6.777  77.782  27.842  1    127.47 ? 266 GLY B C   1 -0.062 0.713  0.07   
ATOM   5116  O  O   . GLY B 1 277 ? -6.587  78.834  27.234  1    127.93 ? 266 GLY B O   1 -0.06  0.722  0.068  
ATOM   5117  N  N   . VAL B 1 278 ? -6.254  76.611  27.446  1    126.46 ? 267 VAL B N   1 -0.057 0.702  0.069  
ATOM   5118  C  CA  . VAL B 1 278 ? -5.31   76.512  26.334  1    125.46 ? 267 VAL B CA  1 -0.049 0.701  0.066  
ATOM   5119  C  C   . VAL B 1 278 ? -6.045  76.212  25.036  1    128.45 ? 267 VAL B C   1 -0.055 0.698  0.063  
ATOM   5120  O  O   . VAL B 1 278 ? -6.937  75.354  24.99   1    127.01 ? 267 VAL B O   1 -0.064 0.691  0.062  
ATOM   5121  C  CB  . VAL B 1 278 ? -4.24   75.441  26.617  1    122.4  ? 267 VAL B CB  1 -0.039 0.691  0.066  
ATOM   5122  C  CG1 . VAL B 1 278 ? -3.159  76.009  27.501  1    125.79 ? 267 VAL B CG1 1 -0.029 0.697  0.069  
ATOM   5123  C  CG2 . VAL B 1 278 ? -4.867  74.221  27.266  1    120.8  ? 267 VAL B CG2 1 -0.045 0.68   0.068  
ATOM   5124  N  N   . ASP B 1 279 ? -5.666  76.935  23.971  1    130.44 ? 268 ASP B N   1 -0.052 0.705  0.06   
ATOM   5125  C  CA  . ASP B 1 279 ? -6.081  76.602  22.612  1    128.54 ? 268 ASP B CA  1 -0.056 0.702  0.056  
ATOM   5126  C  C   . ASP B 1 279 ? -5.495  75.245  22.241  1    131.44 ? 268 ASP B C   1 -0.05  0.69   0.056  
ATOM   5127  O  O   . ASP B 1 279 ? -4.271  75.077  22.241  1    134.51 ? 268 ASP B O   1 -0.039 0.688  0.056  
ATOM   5128  C  CB  . ASP B 1 279 ? -5.608  77.69   21.636  1    133.14 ? 268 ASP B CB  1 -0.051 0.712  0.054  
ATOM   5129  C  CG  . ASP B 1 279 ? -6.038  77.437  20.158  1    136.37 ? 268 ASP B CG  1 -0.055 0.71   0.05   
ATOM   5130  O  OD1 . ASP B 1 279 ? -6.645  76.385  19.852  1    132.56 ? 268 ASP B OD1 1 -0.061 0.7    0.05   
ATOM   5131  O  OD2 . ASP B 1 279 ? -5.77   78.312  19.291  1    131.92 ? 268 ASP B OD2 1 -0.053 0.718  0.048  
ATOM   5132  N  N   . ILE B 1 280 ? -6.355  74.27   21.946  1    129.96 ? 269 ILE B N   1 -0.058 0.681  0.055  
ATOM   5133  C  CA  . ILE B 1 280 ? -5.888  72.947  21.538  1    133.91 ? 269 ILE B CA  1 -0.054 0.668  0.054  
ATOM   5134  C  C   . ILE B 1 280 ? -6.032  72.697  20.044  1    132.76 ? 269 ILE B C   1 -0.055 0.666  0.05   
ATOM   5135  O  O   . ILE B 1 280 ? -5.407  71.751  19.532  1    132.05 ? 269 ILE B O   1 -0.05  0.658  0.049  
ATOM   5136  C  CB  . ILE B 1 280 ? -6.579  71.815  22.334  1    130.07 ? 269 ILE B CB  1 -0.06  0.658  0.056  
ATOM   5137  C  CG1 . ILE B 1 280 ? -8.102  71.967  22.326  1    129.86 ? 269 ILE B CG1 1 -0.074 0.66   0.056  
ATOM   5138  C  CG2 . ILE B 1 280 ? -6.042  71.758  23.751  1    122.7  ? 269 ILE B CG2 1 -0.055 0.658  0.059  
ATOM   5139  C  CD1 . ILE B 1 280 ? -8.795  71.311  21.15   1    120.31 ? 269 ILE B CD1 1 -0.081 0.654  0.053  
ATOM   5140  N  N   . GLY B 1 281 ? -6.822  73.504  19.329  1    135.13 ? 270 GLY B N   1 -0.063 0.674  0.048  
ATOM   5141  C  CA  . GLY B 1 281 ? -6.995  73.337  17.896  1    127.56 ? 270 GLY B CA  1 -0.064 0.672  0.045  
ATOM   5142  C  C   . GLY B 1 281 ? -7.824  74.425  17.25   1    123.13 ? 270 GLY B C   1 -0.072 0.682  0.043  
ATOM   5143  O  O   . GLY B 1 281 ? -7.496  75.613  17.339  1    124.81 ? 270 GLY B O   1 -0.069 0.693  0.043  
ATOM   5144  N  N   . LYS B 1 282 ? -8.931  74.02   16.624  1    125.91 ? 271 LYS B N   1 -0.082 0.678  0.042  
ATOM   5145  C  CA  . LYS B 1 282 ? -9.748  74.865  15.753  1    127.25 ? 271 LYS B CA  1 -0.089 0.686  0.039  
ATOM   5146  C  C   . LYS B 1 282 ? -10.408 76.037  16.488  1    122.45 ? 271 LYS B C   1 -0.095 0.697  0.041  
ATOM   5147  O  O   . LYS B 1 282 ? -11.624 76.26   16.365  1    111.11 ? 271 LYS B O   1 -0.107 0.699  0.041  
ATOM   5148  C  CB  . LYS B 1 282 ? -10.799 73.985  15.055  1    127.2  ? 271 LYS B CB  1 -0.099 0.678  0.038  
ATOM   5149  C  CG  . LYS B 1 282 ? -10.217 72.715  14.376  1    123.01 ? 271 LYS B CG  1 -0.094 0.666  0.036  
ATOM   5150  C  CD  . LYS B 1 282 ? -11.325 71.785  13.837  1    125.61 ? 271 LYS B CD  1 -0.104 0.658  0.035  
ATOM   5151  C  CE  . LYS B 1 282 ? -10.884 70.308  13.789  1    124.34 ? 271 LYS B CE  1 -0.1   0.644  0.034  
ATOM   5152  N  NZ  . LYS B 1 282 ? -12.032 69.332  13.653  1    109.28 ? 271 LYS B NZ  1 -0.11  0.635  0.034  
ATOM   5153  N  N   . ASN B 1 283 ? -9.592  76.814  17.212  1    126.34 ? 272 ASN B N   1 -0.088 0.704  0.043  
ATOM   5154  C  CA  . ASN B 1 283 ? -10.038 77.869  18.127  1    125.57 ? 272 ASN B CA  1 -0.092 0.714  0.045  
ATOM   5155  C  C   . ASN B 1 283 ? -11.067 77.317  19.116  1    129.49 ? 272 ASN B C   1 -0.101 0.709  0.048  
ATOM   5156  O  O   . ASN B 1 283 ? -12.281 77.538  19.038  1    129.55 ? 272 ASN B O   1 -0.113 0.711  0.048  
ATOM   5157  C  CB  . ASN B 1 283 ? -10.566 79.067  17.346  1    123.99 ? 272 ASN B CB  1 -0.097 0.725  0.043  
ATOM   5158  C  CG  . ASN B 1 283 ? -9.538  79.606  16.396  1    131.99 ? 272 ASN B CG  1 -0.087 0.73   0.041  
ATOM   5159  O  OD1 . ASN B 1 283 ? -8.331  79.409  16.607  1    131.88 ? 272 ASN B OD1 1 -0.076 0.728  0.041  
ATOM   5160  N  ND2 . ASN B 1 283 ? -9.993  80.271  15.331  1    126.43 ? 272 ASN B ND2 1 -0.092 0.736  0.038  
ATOM   5161  N  N   . ILE B 1 284 ? -10.516 76.584  20.07   1    124.67 ? 273 ILE B N   1 -0.096 0.702  0.05   
ATOM   5162  C  CA  . ILE B 1 284 ? -11.303 75.662  20.869  1    123.43 ? 273 ILE B CA  1 -0.104 0.693  0.052  
ATOM   5163  C  C   . ILE B 1 284 ? -10.456 75.35   22.096  1    123.34 ? 273 ILE B C   1 -0.096 0.691  0.055  
ATOM   5164  O  O   . ILE B 1 284 ? -9.381  74.746  21.989  1    123.9  ? 273 ILE B O   1 -0.086 0.685  0.055  
ATOM   5165  C  CB  . ILE B 1 284 ? -11.688 74.428  20.014  1    120.19 ? 273 ILE B CB  1 -0.107 0.682  0.05   
ATOM   5166  C  CG1 . ILE B 1 284 ? -12.375 73.306  20.808  1    124.44 ? 273 ILE B CG1 1 -0.113 0.672  0.052  
ATOM   5167  C  CG2 . ILE B 1 284 ? -10.484 73.866  19.325  1    124.09 ? 273 ILE B CG2 1 -0.096 0.677  0.048  
ATOM   5168  C  CD1 . ILE B 1 284 ? -12.836 72.085  19.921  1    116.44 ? 273 ILE B CD1 1 -0.118 0.661  0.05   
ATOM   5169  N  N   . HIS B 1 285 ? -10.904 75.821  23.258  1    121.4  ? 274 HIS B N   1 -0.1   0.695  0.058  
ATOM   5170  C  CA  . HIS B 1 285 ? -10.092 75.877  24.465  1    119.48 ? 274 HIS B CA  1 -0.092 0.695  0.061  
ATOM   5171  C  C   . HIS B 1 285 ? -10.572 74.865  25.495  1    118.36 ? 274 HIS B C   1 -0.097 0.686  0.064  
ATOM   5172  O  O   . HIS B 1 285 ? -11.723 74.415  25.475  1    116.91 ? 274 HIS B O   1 -0.107 0.682  0.064  
ATOM   5173  C  CB  . HIS B 1 285 ? -10.121 77.282  25.084  1    120.54 ? 274 HIS B CB  1 -0.093 0.708  0.063  
ATOM   5174  C  CG  . HIS B 1 285 ? -9.298  78.292  24.345  1    127.59 ? 274 HIS B CG  1 -0.085 0.717  0.061  
ATOM   5175  N  ND1 . HIS B 1 285 ? -9.243  78.349  22.965  1    126.1  ? 274 HIS B ND1 1 -0.085 0.718  0.057  
ATOM   5176  C  CD2 . HIS B 1 285 ? -8.502  79.293  24.796  1    127.33 ? 274 HIS B CD2 1 -0.078 0.727  0.062  
ATOM   5177  C  CE1 . HIS B 1 285 ? -8.445  79.338  22.599  1    123.84 ? 274 HIS B CE1 1 -0.077 0.727  0.056  
ATOM   5178  N  NE2 . HIS B 1 285 ? -7.979  79.923  23.69   1    134.12 ? 274 HIS B NE2 1 -0.073 0.732  0.059  
ATOM   5179  N  N   . VAL B 1 286 ? -9.669  74.532  26.414  1    118.52 ? 275 VAL B N   1 -0.089 0.683  0.066  
ATOM   5180  C  CA  . VAL B 1 286 ? -9.943  73.588  27.49   1    115.92 ? 275 VAL B CA  1 -0.091 0.674  0.069  
ATOM   5181  C  C   . VAL B 1 286 ? -9.426  74.168  28.798  1    118.87 ? 275 VAL B C   1 -0.086 0.68   0.072  
ATOM   5182  O  O   . VAL B 1 286 ? -8.325  74.729  28.848  1    117.37 ? 275 VAL B O   1 -0.076 0.685  0.072  
ATOM   5183  C  CB  . VAL B 1 286 ? -9.305  72.214  27.209  1    111.9  ? 275 VAL B CB  1 -0.085 0.662  0.068  
ATOM   5184  C  CG1 . VAL B 1 286 ? -7.863  72.388  26.823  1    117.95 ? 275 VAL B CG1 1 -0.072 0.663  0.067  
ATOM   5185  C  CG2 . VAL B 1 286 ? -9.417  71.315  28.42   1    118.38 ? 275 VAL B CG2 1 -0.086 0.654  0.071  
ATOM   5186  N  N   . TRP B 1 287 ? -10.225 74.033  29.855  1    114.44 ? 276 TRP B N   1 -0.094 0.678  0.075  
ATOM   5187  C  CA  . TRP B 1 287 ? -9.829  74.399  31.206  1    118.38 ? 276 TRP B CA  1 -0.09  0.682  0.078  
ATOM   5188  C  C   . TRP B 1 287 ? -9.731  73.145  32.07   1    120.96 ? 276 TRP B C   1 -0.089 0.67   0.08   
ATOM   5189  O  O   . TRP B 1 287 ? -10.427 72.152  31.826  1    123.8  ? 276 TRP B O   1 -0.096 0.661  0.079  
ATOM   5190  C  CB  . TRP B 1 287 ? -10.824 75.384  31.825  1    114.19 ? 276 TRP B CB  1 -0.099 0.691  0.079  
ATOM   5191  C  CG  . TRP B 1 287 ? -10.836 76.716  31.154  1    115.67 ? 276 TRP B CG  1 -0.099 0.703  0.078  
ATOM   5192  C  CD1 . TRP B 1 287 ? -10.265 77.87   31.61   1    117.44 ? 276 TRP B CD1 1 -0.094 0.714  0.079  
ATOM   5193  C  CD2 . TRP B 1 287 ? -11.438 77.037  29.896  1    119.18 ? 276 TRP B CD2 1 -0.105 0.706  0.075  
ATOM   5194  N  NE1 . TRP B 1 287 ? -10.487 78.893  30.72   1    117.62 ? 276 TRP B NE1 1 -0.096 0.723  0.077  
ATOM   5195  C  CE2 . TRP B 1 287 ? -11.203 78.405  29.658  1    117.42 ? 276 TRP B CE2 1 -0.103 0.719  0.074  
ATOM   5196  C  CE3 . TRP B 1 287 ? -12.158 76.301  28.95   1    112.13 ? 276 TRP B CE3 1 -0.111 0.699  0.072  
ATOM   5197  C  CZ2 . TRP B 1 287 ? -11.659 79.046  28.521  1    112.55 ? 276 TRP B CZ2 1 -0.107 0.724  0.071  
ATOM   5198  C  CZ3 . TRP B 1 287 ? -12.607 76.939  27.829  1    112.28 ? 276 TRP B CZ3 1 -0.116 0.705  0.069  
ATOM   5199  C  CH2 . TRP B 1 287 ? -12.358 78.299  27.619  1    113.91 ? 276 TRP B CH2 1 -0.113 0.718  0.069  
ATOM   5200  N  N   . HIS B 1 288 ? -8.856  73.193  33.08   1    115.53 ? 277 HIS B N   1 -0.081 0.671  0.083  
ATOM   5201  C  CA  . HIS B 1 288 ? -8.638  72.069  33.989  1    116.54 ? 277 HIS B CA  1 -0.079 0.66   0.085  
ATOM   5202  C  C   . HIS B 1 288 ? -8.816  72.518  35.433  1    109.18 ? 277 HIS B C   1 -0.081 0.665  0.088  
ATOM   5203  O  O   . HIS B 1 288 ? -8.141  73.444  35.892  1    104.7  ? 277 HIS B O   1 -0.075 0.673  0.09   
ATOM   5204  C  CB  . HIS B 1 288 ? -7.253  71.455  33.785  1    116.22 ? 277 HIS B CB  1 -0.066 0.655  0.084  
ATOM   5205  C  CG  . HIS B 1 288 ? -7.134  70.681  32.514  1    121.03 ? 277 HIS B CG  1 -0.065 0.648  0.081  
ATOM   5206  N  ND1 . HIS B 1 288 ? -6.164  70.938  31.565  1    126.64 ? 277 HIS B ND1 1 -0.056 0.65   0.079  
ATOM   5207  C  CD2 . HIS B 1 288 ? -7.881  69.665  32.022  1    126.03 ? 277 HIS B CD2 1 -0.072 0.638  0.08   
ATOM   5208  C  CE1 . HIS B 1 288 ? -6.319  70.113  30.544  1    127.38 ? 277 HIS B CE1 1 -0.058 0.643  0.076  
ATOM   5209  N  NE2 . HIS B 1 288 ? -7.353  69.33   30.794  1    133.93 ? 277 HIS B NE2 1 -0.067 0.635  0.077  
ATOM   5210  N  N   . HIS B 1 289 ? -9.746  71.874  36.135  1    107.67 ? 278 HIS B N   1 -0.089 0.659  0.09   
ATOM   5211  C  CA  . HIS B 1 289 ? -9.963  72.062  37.564  1    110.32 ? 278 HIS B CA  1 -0.091 0.66   0.094  
ATOM   5212  C  C   . HIS B 1 289 ? -10.03  70.671  38.174  1    108.84 ? 278 HIS B C   1 -0.092 0.648  0.095  
ATOM   5213  O  O   . HIS B 1 289 ? -11.036 69.971  38.008  1    106.4  ? 278 HIS B O   1 -0.101 0.641  0.095  
ATOM   5214  C  CB  . HIS B 1 289 ? -11.234 72.861  37.853  1    104.62 ? 278 HIS B CB  1 -0.103 0.668  0.095  
ATOM   5215  C  CG  . HIS B 1 289 ? -11.453 73.122  39.311  1    117.87 ? 278 HIS B CG  1 -0.105 0.67   0.098  
ATOM   5216  N  ND1 . HIS B 1 289 ? -12.665 73.535  39.822  1    122.78 ? 278 HIS B ND1 1 -0.116 0.674  0.099  
ATOM   5217  C  CD2 . HIS B 1 289 ? -10.614 73.02   40.371  1    120.15 ? 278 HIS B CD2 1 -0.097 0.669  0.101  
ATOM   5218  C  CE1 . HIS B 1 289 ? -12.563 73.676  41.133  1    122.91 ? 278 HIS B CE1 1 -0.115 0.675  0.103  
ATOM   5219  N  NE2 . HIS B 1 289 ? -11.328 73.371  41.491  1    120.66 ? 278 HIS B NE2 1 -0.104 0.672  0.104  
ATOM   5220  N  N   . ASN B 1 290 ? -8.95   70.264  38.852  1    105.76 ? 279 ASN B N   1 -0.082 0.644  0.097  
ATOM   5221  C  CA  . ASN B 1 290 ? -8.808  68.928  39.433  1    112.78 ? 279 ASN B CA  1 -0.081 0.632  0.098  
ATOM   5222  C  C   . ASN B 1 290 ? -8.929  67.843  38.38   1    108.34 ? 279 ASN B C   1 -0.082 0.622  0.096  
ATOM   5223  O  O   . ASN B 1 290 ? -7.963  67.52   37.682  1    115.84 ? 279 ASN B O   1 -0.073 0.619  0.094  
ATOM   5224  C  CB  . ASN B 1 290 ? -9.858  68.65   40.52   1    117.6  ? 279 ASN B CB  1 -0.09  0.629  0.101  
ATOM   5225  C  CG  . ASN B 1 290 ? -9.811  69.641  41.633  1    112.88 ? 279 ASN B CG  1 -0.09  0.638  0.104  
ATOM   5226  O  OD1 . ASN B 1 290 ? -8.739  70.097  42.016  1    115.49 ? 279 ASN B OD1 1 -0.08  0.642  0.105  
ATOM   5227  N  ND2 . ASN B 1 290 ? -10.98  69.999  42.161  1    113.77 ? 279 ASN B ND2 1 -0.101 0.641  0.105  
ATOM   5228  N  N   . ASN B 1 291 ? -10.113 67.26   38.274  1    103.2  ? 280 ASN B N   1 -0.093 0.616  0.096  
ATOM   5229  C  CA  . ASN B 1 291 ? -10.314 66.138  37.381  1    114.75 ? 280 ASN B CA  1 -0.095 0.606  0.093  
ATOM   5230  C  C   . ASN B 1 291 ? -11.36  66.409  36.305  1    116.05 ? 280 ASN B C   1 -0.104 0.609  0.091  
ATOM   5231  O  O   . ASN B 1 291 ? -11.679 65.502  35.522  1    114.04 ? 280 ASN B O   1 -0.107 0.6    0.089  
ATOM   5232  C  CB  . ASN B 1 291 ? -10.677 64.895  38.207  1    114.52 ? 280 ASN B CB  1 -0.098 0.595  0.095  
ATOM   5233  C  CG  . ASN B 1 291 ? -9.452  64.149  38.694  1    113.25 ? 280 ASN B CG  1 -0.087 0.588  0.097  
ATOM   5234  O  OD1 . ASN B 1 291 ? -8.319  64.615  38.533  1    117.89 ? 280 ASN B OD1 1 -0.076 0.592  0.096  
ATOM   5235  N  ND2 . ASN B 1 291 ? -9.671  62.971  39.277  1    106.01 ? 280 ASN B ND2 1 -0.089 0.577  0.098  
ATOM   5236  N  N   . LEU B 1 292 ? -11.878 67.638  36.23   1    115.95 ? 281 LEU B N   1 -0.109 0.62   0.09   
ATOM   5237  C  CA  . LEU B 1 292 ? -12.862 68.037  35.231  1    113.11 ? 281 LEU B CA  1 -0.118 0.624  0.088  
ATOM   5238  C  C   . LEU B 1 292 ? -12.173 68.713  34.054  1    111.87 ? 281 LEU B C   1 -0.112 0.63   0.085  
ATOM   5239  O  O   . LEU B 1 292 ? -11.399 69.66   34.234  1    109.66 ? 281 LEU B O   1 -0.104 0.638  0.085  
ATOM   5240  C  CB  . LEU B 1 292 ? -13.888 68.986  35.847  1    109.85 ? 281 LEU B CB  1 -0.127 0.632  0.09   
ATOM   5241  C  CG  . LEU B 1 292 ? -14.715 69.83   34.878  1    107.02 ? 281 LEU B CG  1 -0.135 0.64   0.087  
ATOM   5242  C  CD1 . LEU B 1 292 ? -15.562 68.934  33.982  1    110.23 ? 281 LEU B CD1 1 -0.143 0.632  0.085  
ATOM   5243  C  CD2 . LEU B 1 292 ? -15.59  70.791  35.664  1    110.08 ? 281 LEU B CD2 1 -0.143 0.649  0.089  
ATOM   5244  N  N   . ASN B 1 293 ? -12.467 68.237  32.85   1    112.18 ? 282 ASN B N   1 -0.114 0.625  0.082  
ATOM   5245  C  CA  . ASN B 1 293 ? -11.945 68.838  31.624  1    112.25 ? 282 ASN B CA  1 -0.109 0.631  0.079  
ATOM   5246  C  C   . ASN B 1 293 ? -13.096 69.489  30.869  1    108.42 ? 282 ASN B C   1 -0.12  0.637  0.077  
ATOM   5247  O  O   . ASN B 1 293 ? -14.004 68.799  30.389  1    111.99 ? 282 ASN B O   1 -0.128 0.63   0.076  
ATOM   5248  C  CB  . ASN B 1 293 ? -11.243 67.789  30.771  1    116.45 ? 282 ASN B CB  1 -0.103 0.621  0.077  
ATOM   5249  C  CG  . ASN B 1 293 ? -9.978  67.284  31.409  1    115.34 ? 282 ASN B CG  1 -0.091 0.617  0.078  
ATOM   5250  O  OD1 . ASN B 1 293 ? -9.746  67.497  32.596  1    112.74 ? 282 ASN B OD1 1 -0.089 0.619  0.081  
ATOM   5251  N  ND2 . ASN B 1 293 ? -9.139  66.625  30.621  1    125.28 ? 282 ASN B ND2 1 -0.084 0.611  0.076  
ATOM   5252  N  N   . TYR B 1 294 ? -13.054 70.812  30.748  1    101.16 ? 283 TYR B N   1 -0.12  0.649  0.077  
ATOM   5253  C  CA  . TYR B 1 294 ? -14.101 71.556  30.056  1    111.04 ? 283 TYR B CA  1 -0.129 0.656  0.075  
ATOM   5254  C  C   . TYR B 1 294 ? -13.586 72.028  28.695  1    113.59 ? 283 TYR B C   1 -0.125 0.66   0.072  
ATOM   5255  O  O   . TYR B 1 294 ? -12.714 72.904  28.629  1    110.73 ? 283 TYR B O   1 -0.117 0.668  0.071  
ATOM   5256  C  CB  . TYR B 1 294 ? -14.566 72.736  30.898  1    104.58 ? 283 TYR B CB  1 -0.133 0.667  0.077  
ATOM   5257  C  CG  . TYR B 1 294 ? -15.672 73.548  30.266  1    103.15 ? 283 TYR B CG  1 -0.144 0.674  0.076  
ATOM   5258  C  CD1 . TYR B 1 294 ? -16.955 73.036  30.151  1    101.74 ? 283 TYR B CD1 1 -0.155 0.669  0.075  
ATOM   5259  C  CD2 . TYR B 1 294 ? -15.433 74.837  29.798  1    101.38 ? 283 TYR B CD2 1 -0.141 0.686  0.074  
ATOM   5260  C  CE1 . TYR B 1 294 ? -17.974 73.791  29.592  1    105.04 ? 283 TYR B CE1 1 -0.165 0.676  0.074  
ATOM   5261  C  CE2 . TYR B 1 294 ? -16.444 75.6    29.243  1    101.09 ? 283 TYR B CE2 1 -0.151 0.693  0.073  
ATOM   5262  C  CZ  . TYR B 1 294 ? -17.716 75.076  29.137  1    101.23 ? 283 TYR B CZ  1 -0.162 0.688  0.073  
ATOM   5263  O  OH  . TYR B 1 294 ? -18.728 75.838  28.577  1    95.56  ? 283 TYR B OH  1 -0.172 0.695  0.071  
ATOM   5264  N  N   . TYR B 1 295 ? -14.136 71.45   27.617  1    108.31 ? 284 TYR B N   1 -0.13  0.655  0.069  
ATOM   5265  C  CA  . TYR B 1 295 ? -13.872 71.905  26.253  1    108.78 ? 284 TYR B CA  1 -0.127 0.659  0.066  
ATOM   5266  C  C   . TYR B 1 295 ? -14.96  72.88   25.817  1    102.74 ? 284 TYR B C   1 -0.137 0.668  0.064  
ATOM   5267  O  O   . TYR B 1 295 ? -16.154 72.552  25.865  1    99.9   ? 284 TYR B O   1 -0.148 0.665  0.065  
ATOM   5268  C  CB  . TYR B 1 295 ? -13.805 70.734  25.276  1    104.98 ? 284 TYR B CB  1 -0.127 0.648  0.063  
ATOM   5269  C  CG  . TYR B 1 295 ? -12.704 69.76   25.585  1    109.74 ? 284 TYR B CG  1 -0.116 0.639  0.064  
ATOM   5270  C  CD1 . TYR B 1 295 ? -11.408 69.979  25.137  1    108.12 ? 284 TYR B CD1 1 -0.105 0.641  0.063  
ATOM   5271  C  CD2 . TYR B 1 295 ? -12.959 68.619  26.339  1    114.36 ? 284 TYR B CD2 1 -0.119 0.629  0.066  
ATOM   5272  C  CE1 . TYR B 1 295 ? -10.395 69.08   25.426  1    113.96 ? 284 TYR B CE1 1 -0.095 0.633  0.063  
ATOM   5273  C  CE2 . TYR B 1 295 ? -11.957 67.718  26.631  1    117.22 ? 284 TYR B CE2 1 -0.11  0.621  0.066  
ATOM   5274  C  CZ  . TYR B 1 295 ? -10.677 67.954  26.176  1    118.17 ? 284 TYR B CZ  1 -0.098 0.623  0.065  
ATOM   5275  O  OH  . TYR B 1 295 ? -9.679  67.059  26.471  1    124.48 ? 284 TYR B OH  1 -0.089 0.615  0.066  
ATOM   5276  N  N   . ALA B 1 296 ? -14.546 74.071  25.386  1    101.06 ? 285 ALA B N   1 -0.133 0.679  0.063  
ATOM   5277  C  CA  . ALA B 1 296 ? -15.448 75.041  24.776  1    110.92 ? 285 ALA B CA  1 -0.142 0.688  0.062  
ATOM   5278  C  C   . ALA B 1 296 ? -15.243 75.05   23.252  1    107.57 ? 285 ALA B C   1 -0.14  0.688  0.058  
ATOM   5279  O  O   . ALA B 1 296 ? -14.243 75.581  22.753  1    102.68 ? 285 ALA B O   1 -0.131 0.693  0.057  
ATOM   5280  C  CB  . ALA B 1 296 ? -15.239 76.427  25.382  1    105.34 ? 285 ALA B CB  1 -0.14  0.7    0.063  
ATOM   5281  N  N   . VAL B 1 297 ? -16.192 74.448  22.529  1    101.03 ? 286 VAL B N   1 -0.148 0.682  0.056  
ATOM   5282  C  CA  . VAL B 1 297 ? -16.267 74.501  21.07   1    103.52 ? 286 VAL B CA  1 -0.149 0.683  0.053  
ATOM   5283  C  C   . VAL B 1 297 ? -17.061 75.744  20.676  1    100.32 ? 286 VAL B C   1 -0.156 0.694  0.052  
ATOM   5284  O  O   . VAL B 1 297 ? -18.288 75.778  20.817  1    100.67 ? 286 VAL B O   1 -0.168 0.694  0.052  
ATOM   5285  C  CB  . VAL B 1 297 ? -16.934 73.244  20.499  1    102.66 ? 286 VAL B CB  1 -0.155 0.671  0.051  
ATOM   5286  C  CG1 . VAL B 1 297 ? -17.052 73.362  19.016  1    105.12 ? 286 VAL B CG1 1 -0.156 0.672  0.047  
ATOM   5287  C  CG2 . VAL B 1 297 ? -16.184 71.983  20.885  1    101.75 ? 286 VAL B CG2 1 -0.148 0.66   0.052  
ATOM   5288  N  N   . ASP B 1 298 ? -16.379 76.764  20.158  1    101.12 ? 287 ASP B N   1 -0.15  0.703  0.05   
ATOM   5289  C  CA  . ASP B 1 298 ? -17.056 78.008  19.784  1    105.29 ? 287 ASP B CA  1 -0.156 0.715  0.049  
ATOM   5290  C  C   . ASP B 1 298 ? -17.332 78.03   18.286  1    102.67 ? 287 ASP B C   1 -0.159 0.715  0.046  
ATOM   5291  O  O   . ASP B 1 298 ? -16.414 78.201  17.481  1    102.29 ? 287 ASP B O   1 -0.15  0.717  0.044  
ATOM   5292  C  CB  . ASP B 1 298 ? -16.264 79.244  20.179  1    106.86 ? 287 ASP B CB  1 -0.149 0.726  0.05   
ATOM   5293  C  CG  . ASP B 1 298 ? -17.153 80.488  20.262  1    107.96 ? 287 ASP B CG  1 -0.157 0.738  0.051  
ATOM   5294  O  OD1 . ASP B 1 298 ? -18.251 80.502  19.637  1    101.52 ? 287 ASP B OD1 1 -0.167 0.738  0.049  
ATOM   5295  O  OD2 . ASP B 1 298 ? -16.749 81.444  20.964  1    108.69 ? 287 ASP B OD2 1 -0.153 0.746  0.052  
ATOM   5296  N  N   . LEU B 1 299 ? -18.614 77.917  17.931  1    98.74  ? 288 LEU B N   1 -0.171 0.714  0.045  
ATOM   5297  C  CA  . LEU B 1 299 ? -19.023 77.903  16.534  1    102.02 ? 288 LEU B CA  1 -0.174 0.714  0.041  
ATOM   5298  C  C   . LEU B 1 299 ? -18.477 79.098  15.765  1    108.97 ? 288 LEU B C   1 -0.169 0.725  0.039  
ATOM   5299  O  O   . LEU B 1 299 ? -18.009 78.949  14.629  1    119.6  ? 288 LEU B O   1 -0.165 0.723  0.037  
ATOM   5300  C  CB  . LEU B 1 299 ? -20.548 77.865  16.437  1    96.8   ? 288 LEU B CB  1 -0.188 0.714  0.041  
ATOM   5301  C  CG  . LEU B 1 299 ? -21.147 76.638  17.121  1    95.48  ? 288 LEU B CG  1 -0.194 0.702  0.043  
ATOM   5302  C  CD1 . LEU B 1 299 ? -22.66  76.665  17.099  1    93.8   ? 288 LEU B CD1 1 -0.208 0.703  0.043  
ATOM   5303  C  CD2 . LEU B 1 299 ? -20.626 75.379  16.467  1    100.94 ? 288 LEU B CD2 1 -0.189 0.691  0.041  
ATOM   5304  N  N   . SER B 1 300 ? -18.515 80.291  16.358  1    103.05 ? 289 SER B N   1 -0.17  0.736  0.041  
ATOM   5305  C  CA  . SER B 1 300 ? -18.11  81.467  15.599  1    109.31 ? 289 SER B CA  1 -0.166 0.747  0.039  
ATOM   5306  C  C   . SER B 1 300 ? -16.622 81.479  15.286  1    112.18 ? 289 SER B C   1 -0.152 0.747  0.038  
ATOM   5307  O  O   . SER B 1 300 ? -16.193 82.246  14.418  1    121.95 ? 289 SER B O   1 -0.148 0.754  0.036  
ATOM   5308  C  CB  . SER B 1 300 ? -18.463 82.741  16.346  1    110.52 ? 289 SER B CB  1 -0.169 0.758  0.041  
ATOM   5309  O  OG  . SER B 1 300 ? -17.678 82.883  17.514  1    108.83 ? 289 SER B OG  1 -0.162 0.76   0.044  
ATOM   5310  N  N   . LEU B 1 301 ? -15.827 80.668  15.973  1    108.95 ? 290 LEU B N   1 -0.145 0.739  0.04   
ATOM   5311  C  CA  . LEU B 1 301 ? -14.422 80.527  15.632  1    113.93 ? 290 LEU B CA  1 -0.132 0.738  0.039  
ATOM   5312  C  C   . LEU B 1 301 ? -14.128 79.245  14.863  1    117.45 ? 290 LEU B C   1 -0.129 0.726  0.037  
ATOM   5313  O  O   . LEU B 1 301 ? -13.043 79.123  14.286  1    116.53 ? 290 LEU B O   1 -0.12  0.725  0.036  
ATOM   5314  C  CB  . LEU B 1 301 ? -13.573 80.576  16.903  1    116.28 ? 290 LEU B CB  1 -0.124 0.738  0.042  
ATOM   5315  C  CG  . LEU B 1 301 ? -13.563 81.914  17.66   1    115.31 ? 290 LEU B CG  1 -0.124 0.751  0.044  
ATOM   5316  C  CD1 . LEU B 1 301 ? -13.395 83.082  16.69   1    119.44 ? 290 LEU B CD1 1 -0.123 0.761  0.042  
ATOM   5317  C  CD2 . LEU B 1 301 ? -14.796 82.101  18.539  1    117.6  ? 290 LEU B CD2 1 -0.136 0.752  0.046  
ATOM   5318  N  N   . THR B 1 302 ? -15.069 78.302  14.843  1    117.28 ? 291 THR B N   1 -0.138 0.718  0.037  
ATOM   5319  C  CA  . THR B 1 302 ? -14.978 77.03   14.125  1    116.93 ? 291 THR B CA  1 -0.137 0.706  0.035  
ATOM   5320  C  C   . THR B 1 302 ? -15.954 77.139  12.953  1    121.28 ? 291 THR B C   1 -0.146 0.707  0.032  
ATOM   5321  O  O   . THR B 1 302 ? -17.126 76.764  13.053  1    119.22 ? 291 THR B O   1 -0.157 0.703  0.033  
ATOM   5322  C  CB  . THR B 1 302 ? -15.295 75.826  15.048  1    121.39 ? 291 THR B CB  1 -0.14  0.695  0.038  
ATOM   5323  O  OG1 . THR B 1 302 ? -14.289 75.708  16.081  1    106.99 ? 291 THR B OG1 1 -0.131 0.694  0.04   
ATOM   5324  C  CG2 . THR B 1 302 ? -15.359 74.524  14.246  1    121.17 ? 291 THR B CG2 1 -0.141 0.683  0.036  
ATOM   5325  N  N   . SER B 1 303 ? -15.456 77.695  11.855  1    128.49 ? 292 SER B N   1 -0.142 0.712  0.03   
ATOM   5326  C  CA  . SER B 1 303 ? -16.243 77.925  10.653  1    126.15 ? 292 SER B CA  1 -0.149 0.714  0.027  
ATOM   5327  C  C   . SER B 1 303 ? -16.022 76.774  9.678   1    129.28 ? 292 SER B C   1 -0.147 0.704  0.024  
ATOM   5328  O  O   . SER B 1 303 ? -14.877 76.385  9.417   1    126.87 ? 292 SER B O   1 -0.136 0.7    0.024  
ATOM   5329  C  CB  . SER B 1 303 ? -15.853 79.261  10.014  1    129.03 ? 292 SER B CB  1 -0.145 0.726  0.025  
ATOM   5330  O  OG  . SER B 1 303 ? -15.791 80.296  10.992  1    124.5  ? 292 SER B OG  1 -0.145 0.736  0.027  
ATOM   5331  N  N   . ARG B 1 304 ? -17.121 76.252  9.131   1    130.23 ? 293 ARG B N   1 -0.157 0.699  0.023  
ATOM   5332  C  CA  . ARG B 1 304 ? -17.105 74.981  8.423   1    127.13 ? 293 ARG B CA  1 -0.157 0.687  0.021  
ATOM   5333  C  C   . ARG B 1 304 ? -16.249 75.06   7.159   1    124.64 ? 293 ARG B C   1 -0.149 0.688  0.018  
ATOM   5334  O  O   . ARG B 1 304 ? -16.007 76.134  6.612   1    124.25 ? 293 ARG B O   1 -0.147 0.698  0.017  
ATOM   5335  C  CB  . ARG B 1 304 ? -18.53  74.557  8.073   1    122.63 ? 293 ARG B CB  1 -0.17  0.683  0.02   
ATOM   5336  C  CG  . ARG B 1 304 ? -18.66  73.081  7.797   1    122.64 ? 293 ARG B CG  1 -0.171 0.67   0.019  
ATOM   5337  C  CD  . ARG B 1 304 ? -19.67  72.815  6.7     1    126.49 ? 293 ARG B CD  1 -0.18  0.667  0.017  
ATOM   5338  N  NE  . ARG B 1 304 ? -21.023 73.202  7.086   1    122.76 ? 293 ARG B NE  1 -0.193 0.671  0.018  
ATOM   5339  C  CZ  . ARG B 1 304 ? -21.822 72.476  7.858   1    119.64 ? 293 ARG B CZ  1 -0.2   0.664  0.02   
ATOM   5340  N  NH1 . ARG B 1 304 ? -21.412 71.344  8.416   1    110.94 ? 293 ARG B NH1 1 -0.196 0.654  0.021  
ATOM   5341  N  NH2 . ARG B 1 304 ? -23.067 72.894  8.075   1    117.86 ? 293 ARG B NH2 1 -0.211 0.668  0.02   
ATOM   5342  N  N   . LYS B 1 305 ? -15.787 73.894  6.7     1    126.39 ? 294 LYS B N   1 -0.145 0.677  0.017  
ATOM   5343  C  CA  . LYS B 1 305 ? -14.919 73.789  5.52    1    134.76 ? 294 LYS B CA  1 -0.137 0.676  0.014  
ATOM   5344  C  C   . LYS B 1 305 ? -15.728 73.285  4.32    1    135.31 ? 294 LYS B C   1 -0.144 0.672  0.011  
ATOM   5345  O  O   . LYS B 1 305 ? -15.767 72.094  4.006   1    129.34 ? 294 LYS B O   1 -0.144 0.661  0.01   
ATOM   5346  C  CB  . LYS B 1 305 ? -13.724 72.882  5.826   1    136.42 ? 294 LYS B CB  1 -0.126 0.668  0.015  
ATOM   5347  C  CG  . LYS B 1 305 ? -12.938 72.402  4.603   1    130.73 ? 294 LYS B CG  1 -0.119 0.664  0.011  
ATOM   5348  C  CD  . LYS B 1 305 ? -11.445 72.429  4.863   1    137.4  ? 294 LYS B CD  1 -0.105 0.664  0.012  
ATOM   5349  C  CE  . LYS B 1 305 ? -11.052 71.595  6.074   1    128.72 ? 294 LYS B CE  1 -0.101 0.656  0.015  
ATOM   5350  N  NZ  . LYS B 1 305 ? -9.603  71.774  6.387   1    126.69 ? 294 LYS B NZ  1 -0.088 0.658  0.016  
ATOM   5351  N  N   . SER B 1 306 ? -16.382 74.234  3.639   1    137.02 ? 295 SER B N   1 -0.15  0.68   0.009  
ATOM   5352  C  CA  . SER B 1 306 ? -17.153 74.028  2.406   1    142.99 ? 295 SER B CA  1 -0.157 0.678  0.006  
ATOM   5353  C  C   . SER B 1 306 ? -17.993 72.747  2.374   1    146.21 ? 295 SER B C   1 -0.165 0.667  0.006  
ATOM   5354  O  O   . SER B 1 306 ? -19.227 72.813  2.307   1    150.22 ? 295 SER B O   1 -0.176 0.667  0.006  
ATOM   5355  C  CB  . SER B 1 306 ? -16.219 74.051  1.189   1    147.47 ? 295 SER B CB  1 -0.149 0.679  0.003  
ATOM   5356  O  OG  . SER B 1 306 ? -15.815 72.743  0.804   1    144.75 ? 295 SER B OG  1 -0.145 0.667  0.002  
ATOM   5357  N  N   . VAL B 1 307 ? -17.334 71.583  2.395   1    140.51 ? 296 VAL B N   1 -0.159 0.656  0.006  
ATOM   5358  C  CA  . VAL B 1 307 ? -17.989 70.292  2.238   1    133.12 ? 296 VAL B CA  1 -0.165 0.644  0.006  
ATOM   5359  C  C   . VAL B 1 307 ? -17.569 69.391  3.394   1    130.11 ? 296 VAL B C   1 -0.161 0.636  0.008  
ATOM   5360  O  O   . VAL B 1 307 ? -16.453 69.495  3.915   1    130.57 ? 296 VAL B O   1 -0.151 0.637  0.01   
ATOM   5361  C  CB  . VAL B 1 307 ? -17.636 69.665  0.864   1    131.03 ? 296 VAL B CB  1 -0.162 0.638  0.002  
ATOM   5362  C  CG1 . VAL B 1 307 ? -16.329 68.884  0.94    1    127.1  ? 296 VAL B CG1 1 -0.15  0.631  0.002  
ATOM   5363  C  CG2 . VAL B 1 307 ? -18.782 68.813  0.325   1    124.16 ? 296 VAL B CG2 1 -0.172 0.631  0.001  
ATOM   5364  N  N   . GLY B 1 308 ? -18.478 68.519  3.82    1    124.73 ? 297 GLY B N   1 -0.169 0.628  0.01   
ATOM   5365  C  CA  . GLY B 1 308 ? -18.192 67.589  4.896   1    122.22 ? 297 GLY B CA  1 -0.167 0.619  0.012  
ATOM   5366  C  C   . GLY B 1 308 ? -18.814 68.013  6.22    1    119.41 ? 297 GLY B C   1 -0.172 0.623  0.016  
ATOM   5367  O  O   . GLY B 1 308 ? -19.29  69.136  6.402   1    121.64 ? 297 GLY B O   1 -0.177 0.634  0.016  
ATOM   5368  N  N   . VAL B 1 309 ? -18.811 67.063  7.16    1    115.59 ? 298 VAL B N   1 -0.172 0.615  0.018  
ATOM   5369  C  CA  . VAL B 1 309 ? -19.407 67.298  8.473   1    113.81 ? 298 VAL B CA  1 -0.178 0.617  0.021  
ATOM   5370  C  C   . VAL B 1 309 ? -18.722 68.486  9.165   1    111.38 ? 298 VAL B C   1 -0.172 0.628  0.023  
ATOM   5371  O  O   . VAL B 1 309 ? -17.523 68.739  8.975   1    112.54 ? 298 VAL B O   1 -0.161 0.63   0.022  
ATOM   5372  C  CB  . VAL B 1 309 ? -19.311 66.015  9.321   1    115.92 ? 298 VAL B CB  1 -0.177 0.605  0.023  
ATOM   5373  C  CG1 . VAL B 1 309 ? -19.703 66.264  10.771  1    110.04 ? 298 VAL B CG1 1 -0.181 0.607  0.027  
ATOM   5374  C  CG2 . VAL B 1 309 ? -20.185 64.92   8.726   1    111.83 ? 298 VAL B CG2 1 -0.185 0.595  0.022  
ATOM   5375  N  N   . HIS B 1 310 ? -19.509 69.233  9.95    1    112.12 ? 299 HIS B N   1 -0.179 0.634  0.025  
ATOM   5376  C  CA  . HIS B 1 310 ? -19.019 70.403  10.678  1    113.17 ? 299 HIS B CA  1 -0.174 0.645  0.027  
ATOM   5377  C  C   . HIS B 1 310 ? -17.799 70.053  11.53   1    109.09 ? 299 HIS B C   1 -0.163 0.642  0.029  
ATOM   5378  O  O   . HIS B 1 310 ? -17.826 69.047  12.253  1    109.7  ? 299 HIS B O   1 -0.163 0.633  0.031  
ATOM   5379  C  CB  . HIS B 1 310 ? -20.114 70.963  11.589  1    104.36 ? 299 HIS B CB  1 -0.184 0.65   0.029  
ATOM   5380  C  CG  . HIS B 1 310 ? -19.956 72.42   11.884  1    103.64 ? 299 HIS B CG  1 -0.183 0.664  0.03   
ATOM   5381  N  ND1 . HIS B 1 310 ? -18.859 72.93   12.542  1    105.87 ? 299 HIS B ND1 1 -0.173 0.668  0.031  
ATOM   5382  C  CD2 . HIS B 1 310 ? -20.747 73.48   11.594  1    104.13 ? 299 HIS B CD2 1 -0.19  0.673  0.029  
ATOM   5383  C  CE1 . HIS B 1 310 ? -18.98  74.242  12.645  1    111.4  ? 299 HIS B CE1 1 -0.174 0.68   0.032  
ATOM   5384  N  NE2 . HIS B 1 310 ? -20.12  74.6    12.08   1    105.91 ? 299 HIS B NE2 1 -0.184 0.684  0.03   
ATOM   5385  N  N   . PRO B 1 311 ? -16.731 70.863  11.5    1    105.95 ? 300 PRO B N   1 -0.153 0.649  0.029  
ATOM   5386  C  CA  . PRO B 1 311 ? -15.545 70.526  12.31   1    110.58 ? 300 PRO B CA  1 -0.142 0.646  0.031  
ATOM   5387  C  C   . PRO B 1 311 ? -15.854 70.389  13.787  1    112.26 ? 300 PRO B C   1 -0.145 0.645  0.034  
ATOM   5388  O  O   . PRO B 1 311 ? -15.14  69.665  14.491  1    114.25 ? 300 PRO B O   1 -0.139 0.638  0.036  
ATOM   5389  C  CB  . PRO B 1 311 ? -14.587 71.696  12.043  1    110.8  ? 300 PRO B CB  1 -0.134 0.657  0.03   
ATOM   5390  C  CG  . PRO B 1 311 ? -15.033 72.274  10.751  1    116.91 ? 300 PRO B CG  1 -0.138 0.662  0.027  
ATOM   5391  C  CD  . PRO B 1 311 ? -16.521 72.077  10.693  1    113.39 ? 300 PRO B CD  1 -0.151 0.661  0.027  
ATOM   5392  N  N   . ALA B 1 312 ? -16.911 71.054  14.266  1    110.46 ? 301 ALA B N   1 -0.155 0.651  0.036  
ATOM   5393  C  CA  . ALA B 1 312 ? -17.263 71.016  15.682  1    106.52 ? 301 ALA B CA  1 -0.158 0.651  0.039  
ATOM   5394  C  C   . ALA B 1 312 ? -17.726 69.624  16.106  1    107.88 ? 301 ALA B C   1 -0.162 0.638  0.04   
ATOM   5395  O  O   . ALA B 1 312 ? -17.271 69.099  17.132  1    109.01 ? 301 ALA B O   1 -0.158 0.633  0.043  
ATOM   5396  C  CB  . ALA B 1 312 ? -18.342 72.057  15.977  1    103.52 ? 301 ALA B CB  1 -0.168 0.66   0.04   
ATOM   5397  N  N   . LEU B 1 313 ? -18.633 69.009  15.33   1    100.93 ? 302 LEU B N   1 -0.171 0.632  0.038  
ATOM   5398  C  CA  . LEU B 1 313 ? -19.11  67.667  15.664  1    95.56  ? 302 LEU B CA  1 -0.175 0.62   0.039  
ATOM   5399  C  C   . LEU B 1 313 ? -18.089 66.582  15.352  1    103.19 ? 302 LEU B C   1 -0.166 0.61   0.038  
ATOM   5400  O  O   . LEU B 1 313 ? -18.163 65.503  15.943  1    103.88 ? 302 LEU B O   1 -0.166 0.6    0.04   
ATOM   5401  C  CB  . LEU B 1 313 ? -20.408 67.356  14.933  1    85.54  ? 302 LEU B CB  1 -0.187 0.617  0.037  
ATOM   5402  C  CG  . LEU B 1 313 ? -21.45  68.442  15.141  1    97.42  ? 302 LEU B CG  1 -0.197 0.627  0.038  
ATOM   5403  C  CD1 . LEU B 1 313 ? -22.574 68.347  14.109  1    93.19  ? 302 LEU B CD1 1 -0.207 0.626  0.035  
ATOM   5404  C  CD2 . LEU B 1 313 ? -21.998 68.375  16.583  1    105.34 ? 302 LEU B CD2 1 -0.202 0.627  0.041  
ATOM   5405  N  N   . LEU B 1 314 ? -17.149 66.827  14.432  1    107.22 ? 303 LEU B N   1 -0.157 0.612  0.036  
ATOM   5406  C  CA  . LEU B 1 314 ? -16.06  65.872  14.252  1    109.27 ? 303 LEU B CA  1 -0.147 0.604  0.036  
ATOM   5407  C  C   . LEU B 1 314 ? -15.194 65.802  15.508  1    113.39 ? 303 LEU B C   1 -0.139 0.603  0.039  
ATOM   5408  O  O   . LEU B 1 314 ? -14.823 64.71   15.955  1    112.43 ? 303 LEU B O   1 -0.136 0.593  0.04   
ATOM   5409  C  CB  . LEU B 1 314 ? -15.217 66.24   13.025  1    113.13 ? 303 LEU B CB  1 -0.139 0.607  0.033  
ATOM   5410  C  CG  . LEU B 1 314 ? -15.733 66.053  11.578  1    112.32 ? 303 LEU B CG  1 -0.144 0.605  0.029  
ATOM   5411  C  CD1 . LEU B 1 314 ? -14.544 66.098  10.624  1    113.22 ? 303 LEU B CD1 1 -0.133 0.606  0.027  
ATOM   5412  C  CD2 . LEU B 1 314 ? -16.549 64.777  11.35   1    105.55 ? 303 LEU B CD2 1 -0.152 0.594  0.028  
ATOM   5413  N  N   . PHE B 1 315 ? -14.896 66.963  16.105  1    114    ? 304 PHE B N   1 -0.137 0.614  0.04   
ATOM   5414  C  CA  . PHE B 1 315 ? -14.065 67.016  17.304  1    113.11 ? 304 PHE B CA  1 -0.129 0.614  0.043  
ATOM   5415  C  C   . PHE B 1 315 ? -14.757 66.36   18.489  1    112.93 ? 304 PHE B C   1 -0.135 0.608  0.046  
ATOM   5416  O  O   . PHE B 1 315 ? -14.119 65.636  19.265  1    111.9  ? 304 PHE B O   1 -0.129 0.601  0.048  
ATOM   5417  C  CB  . PHE B 1 315 ? -13.718 68.465  17.645  1    113.41 ? 304 PHE B CB  1 -0.126 0.627  0.044  
ATOM   5418  C  CG  . PHE B 1 315 ? -12.979 68.619  18.952  1    111.3  ? 304 PHE B CG  1 -0.119 0.629  0.047  
ATOM   5419  C  CD1 . PHE B 1 315 ? -11.596 68.516  18.992  1    111.79 ? 304 PHE B CD1 1 -0.106 0.628  0.047  
ATOM   5420  C  CD2 . PHE B 1 315 ? -13.667 68.861  20.133  1    112.26 ? 304 PHE B CD2 1 -0.125 0.631  0.05   
ATOM   5421  C  CE1 . PHE B 1 315 ? -10.91  68.656  20.169  1    116.04 ? 304 PHE B CE1 1 -0.1   0.629  0.05   
ATOM   5422  C  CE2 . PHE B 1 315 ? -12.985 69.001  21.33   1    114.8  ? 304 PHE B CE2 1 -0.119 0.632  0.053  
ATOM   5423  C  CZ  . PHE B 1 315 ? -11.602 68.901  21.347  1    117.52 ? 304 PHE B CZ  1 -0.106 0.631  0.053  
ATOM   5424  N  N   . ALA B 1 316 ? -16.05  66.644  18.674  1    106.88 ? 305 ALA B N   1 -0.147 0.611  0.047  
ATOM   5425  C  CA  . ALA B 1 316 ? -16.834 65.927  19.668  1    101.68 ? 305 ALA B CA  1 -0.154 0.604  0.049  
ATOM   5426  C  C   . ALA B 1 316 ? -16.647 64.419  19.532  1    110.76 ? 305 ALA B C   1 -0.153 0.59   0.049  
ATOM   5427  O  O   . ALA B 1 316 ? -16.605 63.698  20.543  1    102.5  ? 305 ALA B O   1 -0.152 0.584  0.051  
ATOM   5428  C  CB  . ALA B 1 316 ? -18.306 66.31   19.53   1    98.94  ? 305 ALA B CB  1 -0.168 0.608  0.049  
ATOM   5429  N  N   . LEU B 1 317 ? -16.487 63.934  18.29   1    114.53 ? 306 LEU B N   1 -0.151 0.586  0.046  
ATOM   5430  C  CA  . LEU B 1 317 ? -16.316 62.506  18.031  1    112.35 ? 306 LEU B CA  1 -0.15  0.573  0.045  
ATOM   5431  C  C   . LEU B 1 317 ? -14.877 62.045  18.269  1    116.51 ? 306 LEU B C   1 -0.136 0.569  0.046  
ATOM   5432  O  O   . LEU B 1 317 ? -14.652 61.054  18.975  1    117.54 ? 306 LEU B O   1 -0.134 0.56   0.047  
ATOM   5433  C  CB  . LEU B 1 317 ? -16.762 62.181  16.612  1    109.01 ? 306 LEU B CB  1 -0.154 0.57   0.041  
ATOM   5434  C  CG  . LEU B 1 317 ? -18.265 62.36   16.403  1    110.97 ? 306 LEU B CG  1 -0.167 0.571  0.041  
ATOM   5435  C  CD1 . LEU B 1 317 ? -18.682 62.005  14.983  1    111.39 ? 306 LEU B CD1 1 -0.171 0.568  0.037  
ATOM   5436  C  CD2 . LEU B 1 317 ? -19.031 61.531  17.404  1    110.67 ? 306 LEU B CD2 1 -0.174 0.564  0.043  
ATOM   5437  N  N   . GLU B 1 318 ? -13.888 62.742  17.685  1    116.07 ? 307 GLU B N   1 -0.127 0.575  0.044  
ATOM   5438  C  CA  . GLU B 1 318 ? -12.49  62.452  18.009  1    117.62 ? 307 GLU B CA  1 -0.114 0.572  0.045  
ATOM   5439  C  C   . GLU B 1 318 ? -12.279 62.374  19.515  1    119.43 ? 307 GLU B C   1 -0.113 0.572  0.049  
ATOM   5440  O  O   . GLU B 1 318 ? -11.47  61.568  19.985  1    120.33 ? 307 GLU B O   1 -0.105 0.564  0.05   
ATOM   5441  C  CB  . GLU B 1 318 ? -11.552 63.517  17.423  1    115.41 ? 307 GLU B CB  1 -0.106 0.582  0.044  
ATOM   5442  C  CG  . GLU B 1 318 ? -11.905 63.967  16.016  1    125.33 ? 307 GLU B CG  1 -0.109 0.586  0.04   
ATOM   5443  C  CD  . GLU B 1 318 ? -10.874 64.903  15.407  1    135.79 ? 307 GLU B CD  1 -0.1   0.595  0.038  
ATOM   5444  O  OE1 . GLU B 1 318 ? -10.004 65.373  16.175  1    149.67 ? 307 GLU B OE1 1 -0.092 0.599  0.04   
ATOM   5445  O  OE2 . GLU B 1 318 ? -10.926 65.164  14.177  1    116.91 ? 307 GLU B OE2 1 -0.1   0.597  0.035  
ATOM   5446  N  N   . GLN B 1 319 ? -13.009 63.194  20.286  1    117.18 ? 308 GLN B N   1 -0.119 0.579  0.051  
ATOM   5447  C  CA  . GLN B 1 319 ? -12.877 63.204  21.738  1    114.33 ? 308 GLN B CA  1 -0.118 0.579  0.054  
ATOM   5448  C  C   . GLN B 1 319 ? -13.545 61.997  22.374  1    118.53 ? 308 GLN B C   1 -0.124 0.568  0.056  
ATOM   5449  O  O   . GLN B 1 319 ? -12.947 61.332  23.229  1    124.35 ? 308 GLN B O   1 -0.119 0.562  0.058  
ATOM   5450  C  CB  . GLN B 1 319 ? -13.453 64.493  22.32   1    108.65 ? 308 GLN B CB  1 -0.123 0.591  0.056  
ATOM   5451  C  CG  . GLN B 1 319 ? -12.456 65.621  22.291  1    112.1  ? 308 GLN B CG  1 -0.114 0.601  0.056  
ATOM   5452  C  CD  . GLN B 1 319 ? -11.039 65.116  22.478  1    115.87 ? 308 GLN B CD  1 -0.101 0.597  0.056  
ATOM   5453  O  OE1 . GLN B 1 319 ? -10.655 64.678  23.568  1    116.45 ? 308 GLN B OE1 1 -0.098 0.593  0.059  
ATOM   5454  N  NE2 . GLN B 1 319 ? -10.256 65.153  21.406  1    111.84 ? 308 GLN B NE2 1 -0.094 0.597  0.053  
ATOM   5455  N  N   . LEU B 1 320 ? -14.79  61.706  21.989  1    113.27 ? 309 LEU B N   1 -0.136 0.565  0.055  
ATOM   5456  C  CA  . LEU B 1 320 ? -15.455 60.531  22.548  1    113.93 ? 309 LEU B CA  1 -0.142 0.555  0.056  
ATOM   5457  C  C   . LEU B 1 320 ? -14.851 59.242  22.003  1    120.29 ? 309 LEU B C   1 -0.136 0.543  0.055  
ATOM   5458  O  O   . LEU B 1 320 ? -14.839 58.223  22.702  1    119.16 ? 309 LEU B O   1 -0.136 0.534  0.057  
ATOM   5459  C  CB  . LEU B 1 320 ? -16.957 60.595  22.283  1    107.55 ? 309 LEU B CB  1 -0.155 0.555  0.056  
ATOM   5460  C  CG  . LEU B 1 320 ? -17.775 59.3    22.219  1    105.95 ? 309 LEU B CG  1 -0.163 0.543  0.055  
ATOM   5461  C  CD1 . LEU B 1 320 ? -17.912 58.62   23.541  1    101.91 ? 309 LEU B CD1 1 -0.164 0.537  0.059  
ATOM   5462  C  CD2 . LEU B 1 320 ? -19.148 59.593  21.651  1    114.67 ? 309 LEU B CD2 1 -0.175 0.546  0.054  
ATOM   5463  N  N   . LYS B 1 321 ? -14.337 59.265  20.769  1    124.61 ? 310 LYS B N   1 -0.131 0.543  0.052  
ATOM   5464  C  CA  . LYS B 1 321 ? -13.524 58.15   20.294  1    124.74 ? 310 LYS B CA  1 -0.124 0.533  0.051  
ATOM   5465  C  C   . LYS B 1 321 ? -12.312 57.962  21.199  1    126.7  ? 310 LYS B C   1 -0.113 0.531  0.053  
ATOM   5466  O  O   . LYS B 1 321 ? -12.019 56.847  21.649  1    129.63 ? 310 LYS B O   1 -0.11  0.521  0.054  
ATOM   5467  C  CB  . LYS B 1 321 ? -13.101 58.386  18.838  1    125.7  ? 310 LYS B CB  1 -0.12  0.535  0.047  
ATOM   5468  C  CG  . LYS B 1 321 ? -12.41  57.2    18.144  1    130.49 ? 310 LYS B CG  1 -0.114 0.524  0.045  
ATOM   5469  C  CD  . LYS B 1 321 ? -12.097 57.484  16.661  1    129.82 ? 310 LYS B CD  1 -0.111 0.527  0.042  
ATOM   5470  C  CE  . LYS B 1 321 ? -11.141 58.676  16.487  1    134.49 ? 310 LYS B CE  1 -0.102 0.538  0.041  
ATOM   5471  N  NZ  . LYS B 1 321 ? -10.81  58.964  15.048  1    137.72 ? 310 LYS B NZ  1 -0.099 0.54   0.038  
ATOM   5472  N  N   . GLU B 1 322 ? -11.626 59.057  21.527  1    128.75 ? 311 GLU B N   1 -0.107 0.541  0.054  
ATOM   5473  C  CA  . GLU B 1 322 ? -10.456 58.955  22.384  1    132.17 ? 311 GLU B CA  1 -0.096 0.54   0.056  
ATOM   5474  C  C   . GLU B 1 322 ? -10.835 58.57   23.81   1    134.27 ? 311 GLU B C   1 -0.099 0.537  0.059  
ATOM   5475  O  O   . GLU B 1 322 ? -10.215 57.683  24.405  1    137.28 ? 311 GLU B O   1 -0.094 0.529  0.061  
ATOM   5476  C  CB  . GLU B 1 322 ? -9.661  60.266  22.351  1    129.49 ? 311 GLU B CB  1 -0.089 0.552  0.056  
ATOM   5477  C  CG  . GLU B 1 322 ? -8.354  60.242  23.126  1    138.73 ? 311 GLU B CG  1 -0.077 0.552  0.058  
ATOM   5478  C  CD  . GLU B 1 322 ? -7.322  59.234  22.6    1    148.26 ? 311 GLU B CD  1 -0.067 0.543  0.056  
ATOM   5479  O  OE1 . GLU B 1 322 ? -6.14   59.377  23.001  1    154.9  ? 311 GLU B OE1 1 -0.056 0.544  0.057  
ATOM   5480  O  OE2 . GLU B 1 322 ? -7.664  58.309  21.817  1    144.09 ? 311 GLU B OE2 1 -0.07  0.534  0.054  
ATOM   5481  N  N   . SER B 1 323 ? -11.865 59.211  24.371  1    131.03 ? 312 SER B N   1 -0.109 0.543  0.061  
ATOM   5482  C  CA  . SER B 1 323 ? -12.277 58.88   25.734  1    130.4  ? 312 SER B CA  1 -0.113 0.54   0.064  
ATOM   5483  C  C   . SER B 1 323 ? -12.65  57.409  25.881  1    131.14 ? 312 SER B C   1 -0.116 0.526  0.065  
ATOM   5484  O  O   . SER B 1 323 ? -12.552 56.857  26.981  1    136.71 ? 312 SER B O   1 -0.115 0.521  0.067  
ATOM   5485  C  CB  . SER B 1 323 ? -13.447 59.768  26.171  1    130.9  ? 312 SER B CB  1 -0.123 0.548  0.065  
ATOM   5486  O  OG  . SER B 1 323 ? -12.988 61.042  26.608  1    135.7  ? 312 SER B OG  1 -0.119 0.559  0.066  
ATOM   5487  N  N   . ILE B 1 324 ? -13.061 56.751  24.793  1    131.45 ? 313 ILE B N   1 -0.12  0.52   0.062  
ATOM   5488  C  CA  . ILE B 1 324 ? -13.454 55.346  24.877  1    133.18 ? 313 ILE B CA  1 -0.123 0.507  0.062  
ATOM   5489  C  C   . ILE B 1 324 ? -12.229 54.439  24.89   1    138.82 ? 313 ILE B C   1 -0.112 0.499  0.062  
ATOM   5490  O  O   . ILE B 1 324 ? -12.101 53.565  25.76   1    136.04 ? 313 ILE B O   1 -0.111 0.491  0.064  
ATOM   5491  C  CB  . ILE B 1 324 ? -14.42  54.987  23.729  1    128.24 ? 313 ILE B CB  1 -0.132 0.504  0.059  
ATOM   5492  C  CG1 . ILE B 1 324 ? -15.842 55.434  24.087  1    124.56 ? 313 ILE B CG1 1 -0.145 0.508  0.06   
ATOM   5493  C  CG2 . ILE B 1 324 ? -14.368 53.492  23.415  1    125.51 ? 313 ILE B CG2 1 -0.132 0.49   0.058  
ATOM   5494  C  CD1 . ILE B 1 324 ? -16.94  54.83   23.23   1    111.01 ? 313 ILE B CD1 1 -0.155 0.502  0.058  
ATOM   5495  N  N   . ARG B 1 325 ? -11.321 54.624  23.919  1    137.64 ? 314 ARG B N   1 -0.104 0.501  0.06   
ATOM   5496  C  CA  . ARG B 1 325 ? -10.08  53.846  23.896  1    139.45 ? 314 ARG B CA  1 -0.092 0.493  0.06   
ATOM   5497  C  C   . ARG B 1 325 ? -9.307  53.991  25.203  1    145.36 ? 314 ARG B C   1 -0.085 0.495  0.063  
ATOM   5498  O  O   . ARG B 1 325 ? -8.68   53.032  25.67   1    147.02 ? 314 ARG B O   1 -0.08  0.486  0.064  
ATOM   5499  C  CB  . ARG B 1 325 ? -9.204  54.273  22.717  1    143.25 ? 314 ARG B CB  1 -0.084 0.497  0.057  
ATOM   5500  C  CG  . ARG B 1 325 ? -7.885  53.496  22.592  1    145.31 ? 314 ARG B CG  1 -0.072 0.49   0.056  
ATOM   5501  C  CD  . ARG B 1 325 ? -6.914  54.175  21.619  1    145.39 ? 314 ARG B CD  1 -0.063 0.496  0.054  
ATOM   5502  N  NE  . ARG B 1 325 ? -6.38   55.427  22.154  1    150.72 ? 314 ARG B NE  1 -0.058 0.508  0.055  
ATOM   5503  C  CZ  . ARG B 1 325 ? -5.194  55.557  22.74   1    149.68 ? 314 ARG B CZ  1 -0.048 0.509  0.057  
ATOM   5504  N  NH1 . ARG B 1 325 ? -4.363  54.534  22.855  1    146.26 ? 314 ARG B NH1 1 -0.04  0.5    0.057  
ATOM   5505  N  NH2 . ARG B 1 325 ? -4.833  56.746  23.221  1    144.94 ? 314 ARG B NH2 1 -0.044 0.52   0.058  
ATOM   5506  N  N   . GLU B 1 326 ? -9.334  55.185  25.808  1    143.62 ? 315 GLU B N   1 -0.086 0.506  0.064  
ATOM   5507  C  CA  . GLU B 1 326 ? -8.656  55.371  27.083  1    139.56 ? 315 GLU B CA  1 -0.079 0.507  0.068  
ATOM   5508  C  C   . GLU B 1 326 ? -9.315  54.552  28.183  1    140.8  ? 315 GLU B C   1 -0.085 0.5    0.07   
ATOM   5509  O  O   . GLU B 1 326 ? -8.623  54.045  29.07   1    142.87 ? 315 GLU B O   1 -0.079 0.495  0.073  
ATOM   5510  C  CB  . GLU B 1 326 ? -8.634  56.853  27.458  1    145.61 ? 315 GLU B CB  1 -0.079 0.521  0.069  
ATOM   5511  C  CG  . GLU B 1 326 ? -7.985  57.756  26.408  1    146.19 ? 315 GLU B CG  1 -0.073 0.529  0.066  
ATOM   5512  C  CD  . GLU B 1 326 ? -6.473  57.813  26.514  1    154.68 ? 315 GLU B CD  1 -0.059 0.53   0.066  
ATOM   5513  O  OE1 . GLU B 1 326 ? -5.884  56.946  27.198  1    159.57 ? 315 GLU B OE1 1 -0.054 0.522  0.068  
ATOM   5514  O  OE2 . GLU B 1 326 ? -5.875  58.739  25.92   1    155.18 ? 315 GLU B OE2 1 -0.054 0.538  0.065  
ATOM   5515  N  N   . ALA B 1 327 ? -10.639 54.392  28.134  1    142.22 ? 316 ALA B N   1 -0.097 0.498  0.07   
ATOM   5516  C  CA  . ALA B 1 327 ? -11.327 53.588  29.139  1    140.47 ? 316 ALA B CA  1 -0.104 0.491  0.073  
ATOM   5517  C  C   . ALA B 1 327 ? -11.245 52.095  28.835  1    142.16 ? 316 ALA B C   1 -0.103 0.477  0.072  
ATOM   5518  O  O   . ALA B 1 327 ? -11.292 51.279  29.762  1    137.45 ? 316 ALA B O   1 -0.103 0.47   0.074  
ATOM   5519  C  CB  . ALA B 1 327 ? -12.788 54.032  29.252  1    135.83 ? 316 ALA B CB  1 -0.117 0.495  0.073  
ATOM   5520  N  N   . LYS B 1 328 ? -11.12  51.72   27.554  1    142.98 ? 317 LYS B N   1 -0.102 0.474  0.069  
ATOM   5521  C  CA  . LYS B 1 328 ? -11.004 50.309  27.193  1    142.21 ? 317 LYS B CA  1 -0.101 0.461  0.068  
ATOM   5522  C  C   . LYS B 1 328 ? -9.712  49.693  27.706  1    146.2  ? 317 LYS B C   1 -0.089 0.455  0.069  
ATOM   5523  O  O   . LYS B 1 328 ? -9.7    48.517  28.093  1    147.76 ? 317 LYS B O   1 -0.089 0.445  0.07   
ATOM   5524  C  CB  . LYS B 1 328 ? -11.088 50.147  25.676  1    146.02 ? 317 LYS B CB  1 -0.102 0.46   0.064  
ATOM   5525  C  CG  . LYS B 1 328 ? -11.132 48.702  25.18   1    148.1  ? 317 LYS B CG  1 -0.102 0.446  0.063  
ATOM   5526  C  CD  . LYS B 1 328 ? -11.104 48.674  23.66   1    147.5  ? 317 LYS B CD  1 -0.102 0.446  0.059  
ATOM   5527  C  CE  . LYS B 1 328 ? -9.945  49.52   23.133  1    147.03 ? 317 LYS B CE  1 -0.091 0.454  0.058  
ATOM   5528  N  NZ  . LYS B 1 328 ? -10.024 49.792  21.67   1    154.11 ? 317 LYS B NZ  1 -0.092 0.456  0.054  
ATOM   5529  N  N   . ALA B 1 329 ? -8.62   50.461  27.71   1    147.59 ? 318 ALA B N   1 -0.079 0.462  0.069  
ATOM   5530  C  CA  . ALA B 1 329 ? -7.324  49.971  28.162  1    145.92 ? 318 ALA B CA  1 -0.067 0.458  0.07   
ATOM   5531  C  C   . ALA B 1 329 ? -7.168  49.992  29.674  1    138.7  ? 318 ALA B C   1 -0.066 0.458  0.074  
ATOM   5532  O  O   . ALA B 1 329 ? -6.221  49.383  30.183  1    136.7  ? 318 ALA B O   1 -0.057 0.453  0.075  
ATOM   5533  C  CB  . ALA B 1 329 ? -6.197  50.787  27.521  1    149.19 ? 318 ALA B CB  1 -0.057 0.465  0.069  
ATOM   5534  N  N   . LYS B 1 330 ? -8.059  50.668  30.399  1    137.15 ? 319 LYS B N   1 -0.074 0.464  0.076  
ATOM   5535  C  CA  . LYS B 1 330 ? -8.043  50.655  31.857  1    141.19 ? 319 LYS B CA  1 -0.074 0.464  0.08   
ATOM   5536  C  C   . LYS B 1 330 ? -9.157  49.815  32.459  1    138.48 ? 319 LYS B C   1 -0.084 0.457  0.081  
ATOM   5537  O  O   . LYS B 1 330 ? -9.228  49.703  33.689  1    137.89 ? 319 LYS B O   1 -0.085 0.455  0.084  
ATOM   5538  C  CB  . LYS B 1 330 ? -8.147  52.077  32.426  1    139.02 ? 319 LYS B CB  1 -0.075 0.477  0.081  
ATOM   5539  C  CG  . LYS B 1 330 ? -7.304  53.117  31.736  1    137.82 ? 319 LYS B CG  1 -0.067 0.487  0.079  
ATOM   5540  C  CD  . LYS B 1 330 ? -6.094  53.482  32.555  1    133.66 ? 319 LYS B CD  1 -0.056 0.49   0.081  
ATOM   5541  C  CE  . LYS B 1 330 ? -5.469  54.757  32.025  1    137.99 ? 319 LYS B CE  1 -0.05  0.502  0.08   
ATOM   5542  N  NZ  . LYS B 1 330 ? -4.181  55.068  32.708  1    132.57 ? 319 LYS B NZ  1 -0.038 0.505  0.082  
ATOM   5543  N  N   . GLY B 1 331 ? -10.036 49.238  31.642  1    133.69 ? 320 GLY B N   1 -0.092 0.451  0.079  
ATOM   5544  C  CA  . GLY B 1 331 ? -11.133 48.454  32.175  1    130.91 ? 320 GLY B CA  1 -0.102 0.444  0.08   
ATOM   5545  C  C   . GLY B 1 331 ? -12.202 49.233  32.914  1    132.64 ? 320 GLY B C   1 -0.112 0.451  0.082  
ATOM   5546  O  O   . GLY B 1 331 ? -13.04  48.616  33.583  1    127.27 ? 320 GLY B O   1 -0.12  0.446  0.084  
ATOM   5547  N  N   . GLN B 1 332 ? -12.204 50.566  32.823  1    134.76 ? 321 GLN B N   1 -0.112 0.463  0.082  
ATOM   5548  C  CA  . GLN B 1 332 ? -13.259 51.387  33.407  1    131.47 ? 321 GLN B CA  1 -0.122 0.471  0.083  
ATOM   5549  C  C   . GLN B 1 332 ? -14.413 51.568  32.427  1    130.9  ? 321 GLN B C   1 -0.132 0.473  0.081  
ATOM   5550  O  O   . GLN B 1 332 ? -14.226 51.567  31.205  1    131.68 ? 321 GLN B O   1 -0.13  0.473  0.078  
ATOM   5551  C  CB  . GLN B 1 332 ? -12.734 52.766  33.817  1    132.13 ? 321 GLN B CB  1 -0.117 0.484  0.084  
ATOM   5552  C  CG  . GLN B 1 332 ? -11.254 53.004  33.564  1    133.38 ? 321 GLN B CG  1 -0.103 0.486  0.084  
ATOM   5553  C  CD  . GLN B 1 332 ? -10.69  54.115  34.448  1    140.56 ? 321 GLN B CD  1 -0.098 0.496  0.086  
ATOM   5554  O  OE1 . GLN B 1 332 ? -11.381 54.637  35.33   1    140.57 ? 321 GLN B OE1 1 -0.104 0.501  0.088  
ATOM   5555  N  NE2 . GLN B 1 332 ? -9.428  54.474  34.22   1    133.84 ? 321 GLN B NE2 1 -0.086 0.499  0.085  
ATOM   5556  N  N   . LYS B 1 333 ? -15.615 51.739  32.973  1    124.95 ? 322 LYS B N   1 -0.143 0.474  0.082  
ATOM   5557  C  CA  . LYS B 1 333 ? -16.765 52.026  32.133  1    117.99 ? 322 LYS B CA  1 -0.154 0.477  0.08   
ATOM   5558  C  C   . LYS B 1 333 ? -16.949 53.538  31.981  1    118.97 ? 322 LYS B C   1 -0.155 0.491  0.08   
ATOM   5559  O  O   . LYS B 1 333 ? -16.207 54.349  32.543  1    120.2  ? 322 LYS B O   1 -0.149 0.498  0.081  
ATOM   5560  C  CB  . LYS B 1 333 ? -18.017 51.345  32.689  1    118.49 ? 322 LYS B CB  1 -0.165 0.471  0.082  
ATOM   5561  C  CG  . LYS B 1 333 ? -17.99  49.827  32.545  1    119.36 ? 322 LYS B CG  1 -0.165 0.457  0.081  
ATOM   5562  C  CD  . LYS B 1 333 ? -19.284 49.196  33.037  1    125.1  ? 322 LYS B CD  1 -0.177 0.451  0.082  
ATOM   5563  C  CE  . LYS B 1 333 ? -19.322 47.703  32.749  1    122.81 ? 322 LYS B CE  1 -0.177 0.437  0.082  
ATOM   5564  N  NZ  . LYS B 1 333 ? -19.538 47.417  31.302  1    125.25 ? 322 LYS B NZ  1 -0.179 0.435  0.078  
ATOM   5565  N  N   . ILE B 1 334 ? -17.943 53.922  31.182  1    121.68 ? 323 ILE B N   1 -0.164 0.494  0.078  
ATOM   5566  C  CA  . ILE B 1 334 ? -18.177 55.307  30.785  1    118.75 ? 323 ILE B CA  1 -0.167 0.507  0.077  
ATOM   5567  C  C   . ILE B 1 334 ? -19.681 55.533  30.746  1    115.79 ? 323 ILE B C   1 -0.18  0.509  0.077  
ATOM   5568  O  O   . ILE B 1 334 ? -20.44  54.645  30.349  1    120.63 ? 323 ILE B O   1 -0.187 0.501  0.076  
ATOM   5569  C  CB  . ILE B 1 334 ? -17.531 55.63   29.408  1    114.46 ? 323 ILE B CB  1 -0.161 0.51   0.073  
ATOM   5570  C  CG1 . ILE B 1 334 ? -16.011 55.805  29.544  1    121.37 ? 323 ILE B CG1 1 -0.147 0.511  0.074  
ATOM   5571  C  CG2 . ILE B 1 334 ? -18.162 56.861  28.759  1    108.41 ? 323 ILE B CG2 1 -0.166 0.521  0.072  
ATOM   5572  C  CD1 . ILE B 1 334 ? -15.354 56.581  28.421  1    117.54 ? 323 ILE B CD1 1 -0.141 0.519  0.071  
ATOM   5573  N  N   . ALA B 1 335 ? -20.119 56.71   31.174  1    111.21 ? 324 ALA B N   1 -0.184 0.52   0.078  
ATOM   5574  C  CA  . ALA B 1 335 ? -21.496 57.135  30.967  1    112.88 ? 324 ALA B CA  1 -0.197 0.524  0.077  
ATOM   5575  C  C   . ALA B 1 335 ? -21.479 58.373  30.084  1    113.26 ? 324 ALA B C   1 -0.197 0.535  0.075  
ATOM   5576  O  O   . ALA B 1 335 ? -20.698 59.301  30.324  1    115.81 ? 324 ALA B O   1 -0.19  0.543  0.076  
ATOM   5577  C  CB  . ALA B 1 335 ? -22.207 57.405  32.295  1    112.17 ? 324 ALA B CB  1 -0.204 0.526  0.081  
ATOM   5578  N  N   . LEU B 1 336 ? -22.317 58.372  29.051  1    111.29 ? 325 LEU B N   1 -0.205 0.535  0.073  
ATOM   5579  C  CA  . LEU B 1 336 ? -22.337 59.428  28.045  1    105.57 ? 325 LEU B CA  1 -0.205 0.545  0.07   
ATOM   5580  C  C   . LEU B 1 336 ? -23.608 60.248  28.213  1    103.9  ? 325 LEU B C   1 -0.216 0.552  0.07   
ATOM   5581  O  O   . LEU B 1 336 ? -24.706 59.687  28.325  1    102.6  ? 325 LEU B O   1 -0.226 0.547  0.071  
ATOM   5582  C  CB  . LEU B 1 336 ? -22.249 58.831  26.637  1    104.18 ? 325 LEU B CB  1 -0.204 0.539  0.067  
ATOM   5583  C  CG  . LEU B 1 336 ? -22.289 59.731  25.398  1    105    ? 325 LEU B CG  1 -0.204 0.547  0.063  
ATOM   5584  C  CD1 . LEU B 1 336 ? -21.504 61.007  25.612  1    110.19 ? 325 LEU B CD1 1 -0.197 0.559  0.064  
ATOM   5585  C  CD2 . LEU B 1 336 ? -21.692 58.972  24.236  1    112.75 ? 325 LEU B CD2 1 -0.199 0.54   0.061  
ATOM   5586  N  N   . TYR B 1 337 ? -23.454 61.573  28.235  1    100.23 ? 326 TYR B N   1 -0.215 0.564  0.07   
ATOM   5587  C  CA  . TYR B 1 337 ? -24.565 62.484  28.471  1    102.88 ? 326 TYR B CA  1 -0.225 0.573  0.071  
ATOM   5588  C  C   . TYR B 1 337 ? -24.66  63.492  27.334  1    106.61 ? 326 TYR B C   1 -0.226 0.582  0.068  
ATOM   5589  O  O   . TYR B 1 337 ? -23.689 64.196  27.035  1    103.75 ? 326 TYR B O   1 -0.217 0.588  0.068  
ATOM   5590  C  CB  . TYR B 1 337 ? -24.411 63.192  29.82   1    97.77  ? 326 TYR B CB  1 -0.224 0.579  0.074  
ATOM   5591  C  CG  . TYR B 1 337 ? -24.535 62.217  30.976  1    103.38 ? 326 TYR B CG  1 -0.225 0.57   0.077  
ATOM   5592  C  CD1 . TYR B 1 337 ? -23.46  61.411  31.363  1    98.3   ? 326 TYR B CD1 1 -0.215 0.563  0.078  
ATOM   5593  C  CD2 . TYR B 1 337 ? -25.742 62.079  31.661  1    102.4  ? 326 TYR B CD2 1 -0.236 0.569  0.079  
ATOM   5594  C  CE1 . TYR B 1 337 ? -23.587 60.509  32.399  1    104.77 ? 326 TYR B CE1 1 -0.216 0.555  0.081  
ATOM   5595  C  CE2 . TYR B 1 337 ? -25.879 61.186  32.706  1    103.42 ? 326 TYR B CE2 1 -0.237 0.561  0.082  
ATOM   5596  C  CZ  . TYR B 1 337 ? -24.805 60.397  33.075  1    108.72 ? 326 TYR B CZ  1 -0.227 0.553  0.083  
ATOM   5597  O  OH  . TYR B 1 337 ? -24.961 59.501  34.122  1    104.69 ? 326 TYR B OH  1 -0.229 0.545  0.085  
ATOM   5598  N  N   . LEU B 1 338 ? -25.836 63.552  26.702  1    102    ? 327 LEU B N   1 -0.237 0.582  0.067  
ATOM   5599  C  CA  . LEU B 1 338 ? -26.095 64.462  25.592  1    99.63  ? 327 LEU B CA  1 -0.239 0.591  0.064  
ATOM   5600  C  C   . LEU B 1 338 ? -27.15  65.479  26.01   1    96.37  ? 327 LEU B C   1 -0.249 0.6    0.065  
ATOM   5601  O  O   . LEU B 1 338 ? -28.359 65.244  25.854  1    92.63  ? 327 LEU B O   1 -0.26  0.598  0.065  
ATOM   5602  C  CB  . LEU B 1 338 ? -26.522 63.687  24.354  1    100.33 ? 327 LEU B CB  1 -0.243 0.584  0.061  
ATOM   5603  C  CG  . LEU B 1 338 ? -25.699 62.429  24.074  1    99.76  ? 327 LEU B CG  1 -0.236 0.572  0.06   
ATOM   5604  C  CD1 . LEU B 1 338 ? -26.342 61.703  22.907  1    98.75  ? 327 LEU B CD1 1 -0.241 0.565  0.057  
ATOM   5605  C  CD2 . LEU B 1 338 ? -24.216 62.736  23.815  1    94.63  ? 327 LEU B CD2 1 -0.222 0.575  0.059  
ATOM   5606  N  N   . PRO B 1 339 ? -26.74  66.62   26.568  1    97.96  ? 328 PRO B N   1 -0.245 0.611  0.066  
ATOM   5607  C  CA  . PRO B 1 339 ? -27.702 67.703  26.803  1    100.44 ? 328 PRO B CA  1 -0.254 0.62   0.067  
ATOM   5608  C  C   . PRO B 1 339 ? -27.804 68.49   25.515  1    99.78  ? 328 PRO B C   1 -0.255 0.628  0.064  
ATOM   5609  O  O   . PRO B 1 339 ? -27.024 69.408  25.226  1    99.64  ? 328 PRO B O   1 -0.248 0.636  0.063  
ATOM   5610  C  CB  . PRO B 1 339 ? -27.097 68.495  27.972  1    95.06  ? 328 PRO B CB  1 -0.248 0.628  0.07   
ATOM   5611  C  CG  . PRO B 1 339 ? -25.626 68.204  27.91   1    107.75 ? 328 PRO B CG  1 -0.235 0.625  0.07   
ATOM   5612  C  CD  . PRO B 1 339 ? -25.396 66.951  27.068  1    106.45 ? 328 PRO B CD  1 -0.233 0.614  0.068  
ATOM   5613  N  N   . THR B 1 340 ? -28.778 68.077  24.717  1    101.26 ? 329 THR B N   1 -0.264 0.624  0.062  
ATOM   5614  C  CA  . THR B 1 340 ? -28.794 68.32   23.285  1    99.74  ? 329 THR B CA  1 -0.264 0.626  0.058  
ATOM   5615  C  C   . THR B 1 340 ? -29.904 69.288  22.92   1    98.41  ? 329 THR B C   1 -0.274 0.635  0.057  
ATOM   5616  O  O   . THR B 1 340 ? -31.06  69.11   23.335  1    88.9   ? 329 THR B O   1 -0.285 0.633  0.058  
ATOM   5617  C  CB  . THR B 1 340 ? -28.959 66.997  22.541  1    99.43  ? 329 THR B CB  1 -0.265 0.614  0.056  
ATOM   5618  O  OG1 . THR B 1 340 ? -27.836 66.162  22.864  1    100.39 ? 329 THR B OG1 1 -0.255 0.606  0.057  
ATOM   5619  C  CG2 . THR B 1 340 ? -29.048 67.213  21.017  1    102.6  ? 329 THR B CG2 1 -0.266 0.616  0.052  
ATOM   5620  N  N   . GLY B 1 341 ? -29.528 70.323  22.165  1    97.24  ? 330 GLY B N   1 -0.271 0.644  0.055  
ATOM   5621  C  CA  . GLY B 1 341 ? -30.466 71.24   21.552  1    98.96  ? 330 GLY B CA  1 -0.279 0.653  0.054  
ATOM   5622  C  C   . GLY B 1 341 ? -30.446 71.197  20.03   1    103.73 ? 330 GLY B C   1 -0.279 0.652  0.05   
ATOM   5623  O  O   . GLY B 1 341 ? -29.453 70.797  19.397  1    99.09  ? 330 GLY B O   1 -0.27  0.649  0.048  
ATOM   5624  N  N   . TRP B 1 342 ? -31.557 71.612  19.426  1    103.54 ? 331 TRP B N   1 -0.289 0.656  0.049  
ATOM   5625  C  CA  . TRP B 1 342 ? -31.627 71.738  17.982  1    100.64 ? 331 TRP B CA  1 -0.29  0.657  0.045  
ATOM   5626  C  C   . TRP B 1 342 ? -31.54  73.179  17.509  1    102.5  ? 331 TRP B C   1 -0.289 0.671  0.044  
ATOM   5627  O  O   . TRP B 1 342 ? -31.167 73.41   16.348  1    112.09 ? 331 TRP B O   1 -0.286 0.673  0.041  
ATOM   5628  C  CB  . TRP B 1 342 ? -32.903 71.065  17.463  1    99.06  ? 331 TRP B CB  1 -0.302 0.651  0.044  
ATOM   5629  C  CG  . TRP B 1 342 ? -32.736 69.56   17.419  1    102.38 ? 331 TRP B CG  1 -0.3   0.637  0.043  
ATOM   5630  C  CD1 . TRP B 1 342 ? -31.623 68.861  16.997  1    98.91  ? 331 TRP B CD1 1 -0.29  0.631  0.042  
ATOM   5631  C  CD2 . TRP B 1 342 ? -33.688 68.575  17.845  1    96.42  ? 331 TRP B CD2 1 -0.309 0.628  0.045  
ATOM   5632  N  NE1 . TRP B 1 342 ? -31.837 67.506  17.126  1    96.95  ? 331 TRP B NE1 1 -0.292 0.619  0.043  
ATOM   5633  C  CE2 . TRP B 1 342 ? -33.095 67.303  17.638  1    97.57  ? 331 TRP B CE2 1 -0.303 0.617  0.044  
ATOM   5634  C  CE3 . TRP B 1 342 ? -34.983 68.641  18.368  1    91.42  ? 331 TRP B CE3 1 -0.321 0.629  0.046  
ATOM   5635  C  CZ2 . TRP B 1 342 ? -33.76  66.113  17.941  1    97.28  ? 331 TRP B CZ2 1 -0.309 0.606  0.045  
ATOM   5636  C  CZ3 . TRP B 1 342 ? -35.64  67.457  18.67   1    91.86  ? 331 TRP B CZ3 1 -0.327 0.618  0.047  
ATOM   5637  C  CH2 . TRP B 1 342 ? -35.028 66.21   18.458  1    95.58  ? 331 TRP B CH2 1 -0.321 0.607  0.046  
ATOM   5638  N  N   . ASP B 1 343 ? -31.818 74.144  18.387  1    96.22  ? 332 ASP B N   1 -0.292 0.679  0.046  
ATOM   5639  C  CA  . ASP B 1 343 ? -31.533 75.558  18.147  1    98.85  ? 332 ASP B CA  1 -0.289 0.692  0.045  
ATOM   5640  C  C   . ASP B 1 343 ? -30.165 75.806  17.521  1    100.78 ? 332 ASP B C   1 -0.276 0.695  0.044  
ATOM   5641  O  O   . ASP B 1 343 ? -29.935 76.873  16.948  1    111.37 ? 332 ASP B O   1 -0.274 0.704  0.042  
ATOM   5642  C  CB  . ASP B 1 343 ? -31.664 76.371  19.446  1    107.79 ? 332 ASP B CB  1 -0.29  0.7    0.049  
ATOM   5643  C  CG  . ASP B 1 343 ? -30.854 75.816  20.628  1    105.71 ? 332 ASP B CG  1 -0.283 0.695  0.052  
ATOM   5644  O  OD1 . ASP B 1 343 ? -29.811 75.117  20.468  1    101.44 ? 332 ASP B OD1 1 -0.273 0.688  0.051  
ATOM   5645  O  OD2 . ASP B 1 343 ? -31.288 76.143  21.751  1    110.11 ? 332 ASP B OD2 1 -0.287 0.698  0.054  
ATOM   5646  N  N   . SER B 1 344 ? -29.27  74.822  17.584  1    91.26  ? 333 SER B N   1 -0.268 0.686  0.044  
ATOM   5647  C  CA  . SER B 1 344 ? -27.975 74.868  16.925  1    97.69  ? 333 SER B CA  1 -0.256 0.686  0.042  
ATOM   5648  C  C   . SER B 1 344 ? -28.045 74.538  15.436  1    111.17 ? 333 SER B C   1 -0.257 0.683  0.039  
ATOM   5649  O  O   . SER B 1 344 ? -27.025 74.107  14.882  1    109.71 ? 333 SER B O   1 -0.248 0.679  0.037  
ATOM   5650  C  CB  . SER B 1 344 ? -27.026 73.896  17.609  1    99.98  ? 333 SER B CB  1 -0.248 0.677  0.044  
ATOM   5651  O  OG  . SER B 1 344 ? -27.613 72.602  17.67   1    100.15 ? 333 SER B OG  1 -0.253 0.665  0.044  
ATOM   5652  N  N   . HIS B 1 345 ? -29.192 74.721  14.788  1    107.69 ? 334 HIS B N   1 -0.268 0.685  0.037  
ATOM   5653  C  CA  . HIS B 1 345 ? -29.432 74.314  13.411  1    110.77 ? 334 HIS B CA  1 -0.27  0.681  0.033  
ATOM   5654  C  C   . HIS B 1 345 ? -29.509 75.533  12.495  1    114.73 ? 334 HIS B C   1 -0.27  0.692  0.031  
ATOM   5655  O  O   . HIS B 1 345 ? -29.836 76.643  12.929  1    119.29 ? 334 HIS B O   1 -0.273 0.702  0.032  
ATOM   5656  C  CB  . HIS B 1 345 ? -30.736 73.51   13.325  1    113.97 ? 334 HIS B CB  1 -0.282 0.674  0.033  
ATOM   5657  C  CG  . HIS B 1 345 ? -30.879 72.676  12.09   1    107.21 ? 334 HIS B CG  1 -0.283 0.666  0.03   
ATOM   5658  N  ND1 . HIS B 1 345 ? -31.692 73.043  11.04   1    108.2  ? 334 HIS B ND1 1 -0.29  0.669  0.028  
ATOM   5659  C  CD2 . HIS B 1 345 ? -30.356 71.472  11.762  1    104.36 ? 334 HIS B CD2 1 -0.278 0.655  0.029  
ATOM   5660  C  CE1 . HIS B 1 345 ? -31.64  72.113  10.104  1    111.88 ? 334 HIS B CE1 1 -0.29  0.661  0.025  
ATOM   5661  N  NE2 . HIS B 1 345 ? -30.835 71.149  10.515  1    110.26 ? 334 HIS B NE2 1 -0.283 0.652  0.026  
ATOM   5662  N  N   . GLU B 1 346 ? -29.215 75.324  11.207  1    108.09 ? 335 GLU B N   1 -0.268 0.69   0.028  
ATOM   5663  C  CA  . GLU B 1 346 ? -29.35  76.426  10.267  1    107.94 ? 335 GLU B CA  1 -0.269 0.7    0.026  
ATOM   5664  C  C   . GLU B 1 346 ? -30.812 76.814  10.047  1    110.46 ? 335 GLU B C   1 -0.282 0.704  0.025  
ATOM   5665  O  O   . GLU B 1 346 ? -31.081 77.945  9.628   1    109.12 ? 335 GLU B O   1 -0.285 0.714  0.024  
ATOM   5666  C  CB  . GLU B 1 346 ? -28.693 76.057  8.945   1    113.53 ? 335 GLU B CB  1 -0.263 0.697  0.022  
ATOM   5667  C  CG  . GLU B 1 346 ? -29.178 74.715  8.435   1    114.79 ? 335 GLU B CG  1 -0.267 0.685  0.021  
ATOM   5668  C  CD  . GLU B 1 346 ? -28.485 74.24   7.166   1    111.32 ? 335 GLU B CD  1 -0.261 0.68   0.018  
ATOM   5669  O  OE1 . GLU B 1 346 ? -27.333 74.662  6.887   1    115.83 ? 335 GLU B OE1 1 -0.25  0.684  0.017  
ATOM   5670  O  OE2 . GLU B 1 346 ? -29.116 73.422  6.454   1    106.47 ? 335 GLU B OE2 1 -0.267 0.673  0.016  
ATOM   5671  N  N   . ASP B 1 347 ? -31.758 75.918  10.34   1    108.36 ? 336 ASP B N   1 -0.291 0.696  0.026  
ATOM   5672  C  CA  . ASP B 1 347 ? -33.174 76.188  10.134  1    108.46 ? 336 ASP B CA  1 -0.304 0.698  0.025  
ATOM   5673  C  C   . ASP B 1 347 ? -33.919 76.615  11.395  1    115.44 ? 336 ASP B C   1 -0.311 0.702  0.028  
ATOM   5674  O  O   . ASP B 1 347 ? -35.158 76.697  11.356  1    108.11 ? 336 ASP B O   1 -0.322 0.703  0.028  
ATOM   5675  C  CB  . ASP B 1 347 ? -33.885 74.966  9.562   1    113.14 ? 336 ASP B CB  1 -0.311 0.687  0.024  
ATOM   5676  C  CG  . ASP B 1 347 ? -33.256 74.463  8.292   1    115.68 ? 336 ASP B CG  1 -0.305 0.682  0.021  
ATOM   5677  O  OD1 . ASP B 1 347 ? -33.697 73.388  7.822   1    117.56 ? 336 ASP B OD1 1 -0.309 0.673  0.02   
ATOM   5678  O  OD2 . ASP B 1 347 ? -32.32  75.116  7.777   1    119.63 ? 336 ASP B OD2 1 -0.296 0.688  0.019  
ATOM   5679  N  N   . GLU B 1 348 ? -33.214 76.831  12.513  1    117.79 ? 337 GLU B N   1 -0.304 0.704  0.031  
ATOM   5680  C  CA  . GLU B 1 348 ? -33.811 77.472  13.677  1    111.96 ? 337 GLU B CA  1 -0.31  0.71   0.034  
ATOM   5681  C  C   . GLU B 1 348 ? -34.147 78.92   13.337  1    113.86 ? 337 GLU B C   1 -0.313 0.723  0.033  
ATOM   5682  O  O   . GLU B 1 348 ? -33.437 79.579  12.572  1    112.28 ? 337 GLU B O   1 -0.306 0.729  0.031  
ATOM   5683  C  CB  . GLU B 1 348 ? -32.861 77.404  14.885  1    112.51 ? 337 GLU B CB  1 -0.301 0.709  0.037  
ATOM   5684  C  CG  . GLU B 1 348 ? -33.408 77.964  16.222  1    110.19 ? 337 GLU B CG  1 -0.306 0.714  0.041  
ATOM   5685  C  CD  . GLU B 1 348 ? -34.661 77.24   16.731  1    110.62 ? 337 GLU B CD  1 -0.318 0.708  0.042  
ATOM   5686  O  OE1 . GLU B 1 348 ? -35.782 77.594  16.291  1    111.18 ? 337 GLU B OE1 1 -0.328 0.711  0.041  
ATOM   5687  O  OE2 . GLU B 1 348 ? -34.527 76.318  17.572  1    106.48 ? 337 GLU B OE2 1 -0.316 0.699  0.044  
ATOM   5688  N  N   . THR B 1 349 ? -35.266 79.402  13.876  1    117.46 ? 338 THR B N   1 -0.323 0.728  0.035  
ATOM   5689  C  CA  . THR B 1 349 ? -35.7   80.778  13.679  1    116.8  ? 338 THR B CA  1 -0.327 0.74   0.034  
ATOM   5690  C  C   . THR B 1 349 ? -35.728 81.554  14.99   1    117.17 ? 338 THR B C   1 -0.327 0.747  0.037  
ATOM   5691  O  O   . THR B 1 349 ? -36.149 82.719  14.997  1    117.25 ? 338 THR B O   1 -0.331 0.758  0.037  
ATOM   5692  C  CB  . THR B 1 349 ? -37.079 80.803  13.008  1    114.61 ? 338 THR B CB  1 -0.34  0.74   0.032  
ATOM   5693  O  OG1 . THR B 1 349 ? -38.124 80.788  13.994  1    109.4  ? 338 THR B OG1 1 -0.349 0.74   0.035  
ATOM   5694  C  CG2 . THR B 1 349 ? -37.225 79.59   12.089  1    110.58 ? 338 THR B CG2 1 -0.341 0.729  0.03   
ATOM   5695  N  N   . ALA B 1 350 ? -35.263 80.941  16.085  1    119.04 ? 339 ALA B N   1 -0.323 0.742  0.04   
ATOM   5696  C  CA  . ALA B 1 350 ? -35.375 81.493  17.43   1    114.48 ? 339 ALA B CA  1 -0.324 0.747  0.044  
ATOM   5697  C  C   . ALA B 1 350 ? -34.372 82.617  17.658  1    114.95 ? 339 ALA B C   1 -0.315 0.757  0.044  
ATOM   5698  O  O   . ALA B 1 350 ? -33.175 82.455  17.394  1    115.54 ? 339 ALA B O   1 -0.304 0.756  0.043  
ATOM   5699  C  CB  . ALA B 1 350 ? -35.149 80.392  18.461  1    109.4  ? 339 ALA B CB  1 -0.322 0.737  0.046  
ATOM   5700  N  N   . TYR B 1 351 ? -34.864 83.751  18.169  1    118.05 ? 340 TYR B N   1 -0.319 0.768  0.045  
ATOM   5701  C  CA  . TYR B 1 351 ? -33.99  84.882  18.479  1    123.72 ? 340 TYR B CA  1 -0.311 0.778  0.046  
ATOM   5702  C  C   . TYR B 1 351 ? -32.744 84.448  19.259  1    120.95 ? 340 TYR B C   1 -0.3   0.774  0.048  
ATOM   5703  O  O   . TYR B 1 351 ? -31.641 84.933  18.98   1    121.12 ? 340 TYR B O   1 -0.29  0.778  0.047  
ATOM   5704  C  CB  . TYR B 1 351 ? -34.796 85.939  19.252  1    125.1  ? 340 TYR B CB  1 -0.319 0.788  0.048  
ATOM   5705  C  CG  . TYR B 1 351 ? -34.119 87.278  19.551  1    130.84 ? 340 TYR B CG  1 -0.313 0.8    0.049  
ATOM   5706  C  CD1 . TYR B 1 351 ? -32.954 87.333  20.324  1    128.83 ? 340 TYR B CD1 1 -0.302 0.8    0.051  
ATOM   5707  C  CD2 . TYR B 1 351 ? -34.684 88.487  19.124  1    135.28 ? 340 TYR B CD2 1 -0.318 0.811  0.048  
ATOM   5708  C  CE1 . TYR B 1 351 ? -32.342 88.55   20.63   1    130.63 ? 340 TYR B CE1 1 -0.296 0.811  0.052  
ATOM   5709  C  CE2 . TYR B 1 351 ? -34.078 89.721  19.437  1    134.96 ? 340 TYR B CE2 1 -0.312 0.822  0.049  
ATOM   5710  C  CZ  . TYR B 1 351 ? -32.903 89.741  20.193  1    134.36 ? 340 TYR B CZ  1 -0.302 0.822  0.05   
ATOM   5711  O  OH  . TYR B 1 351 ? -32.282 90.94   20.51   1    129.95 ? 340 TYR B OH  1 -0.296 0.833  0.051  
ATOM   5712  N  N   . CYS B 1 352 ? -32.882 83.511  20.202  1    119.2  ? 341 CYS B N   1 -0.301 0.765  0.05   
ATOM   5713  C  CA  . CYS B 1 352 ? -31.751 83.054  21.009  1    119.72 ? 341 CYS B CA  1 -0.291 0.761  0.052  
ATOM   5714  C  C   . CYS B 1 352 ? -30.803 82.112  20.263  1    116.29 ? 341 CYS B C   1 -0.282 0.752  0.051  
ATOM   5715  O  O   . CYS B 1 352 ? -29.782 81.713  20.833  1    113.37 ? 341 CYS B O   1 -0.273 0.749  0.052  
ATOM   5716  C  CB  . CYS B 1 352 ? -32.251 82.383  22.309  1    121.54 ? 341 CYS B CB  1 -0.296 0.755  0.056  
ATOM   5717  S  SG  . CYS B 1 352 ? -33.208 80.803  22.166  1    127.35 ? 341 CYS B SG  1 -0.304 0.74   0.055  
ATOM   5718  N  N   . GLY B 1 353 ? -31.087 81.758  19.008  1    116.83 ? 342 GLY B N   1 -0.285 0.749  0.047  
ATOM   5719  C  CA  . GLY B 1 353 ? -30.199 80.873  18.277  1    109.66 ? 342 GLY B CA  1 -0.277 0.741  0.046  
ATOM   5720  C  C   . GLY B 1 353 ? -29.709 81.419  16.948  1    116.69 ? 342 GLY B C   1 -0.272 0.746  0.042  
ATOM   5721  O  O   . GLY B 1 353 ? -28.794 80.855  16.334  1    116.82 ? 342 GLY B O   1 -0.264 0.741  0.041  
ATOM   5722  N  N   . LYS B 1 354 ? -30.31  82.514  16.478  1    119.22 ? 343 LYS B N   1 -0.278 0.756  0.041  
ATOM   5723  C  CA  . LYS B 1 354 ? -29.992 83.019  15.15   1    117.9  ? 343 LYS B CA  1 -0.275 0.761  0.038  
ATOM   5724  C  C   . LYS B 1 354 ? -29.876 84.534  15.079  1    118.38 ? 343 LYS B C   1 -0.274 0.775  0.038  
ATOM   5725  O  O   . LYS B 1 354 ? -29.521 85.049  14.015  1    119.51 ? 343 LYS B O   1 -0.271 0.779  0.035  
ATOM   5726  C  CB  . LYS B 1 354 ? -31.037 82.535  14.127  1    111.43 ? 343 LYS B CB  1 -0.284 0.756  0.035  
ATOM   5727  C  CG  . LYS B 1 354 ? -30.891 81.065  13.738  1    114.9  ? 343 LYS B CG  1 -0.283 0.743  0.034  
ATOM   5728  C  CD  . LYS B 1 354 ? -30.517 80.879  12.26   1    116.64 ? 343 LYS B CD  1 -0.28  0.741  0.031  
ATOM   5729  C  CE  . LYS B 1 354 ? -31.555 81.501  11.297  1    118.03 ? 343 LYS B CE  1 -0.289 0.747  0.028  
ATOM   5730  N  NZ  . LYS B 1 354 ? -31.48  80.948  9.888   1    125.33 ? 343 LYS B NZ  1 -0.288 0.742  0.025  
ATOM   5731  N  N   . PHE B 1 355 ? -30.154 85.264  16.161  1    117.71 ? 344 PHE B N   1 -0.276 0.781  0.04   
ATOM   5732  C  CA  . PHE B 1 355 ? -29.961 86.714  16.2    1    119.8  ? 344 PHE B CA  1 -0.275 0.795  0.04   
ATOM   5733  C  C   . PHE B 1 355 ? -28.538 86.991  16.672  1    118.38 ? 344 PHE B C   1 -0.262 0.797  0.042  
ATOM   5734  O  O   . PHE B 1 355 ? -28.253 86.978  17.873  1    119.01 ? 344 PHE B O   1 -0.259 0.797  0.045  
ATOM   5735  C  CB  . PHE B 1 355 ? -30.991 87.383  17.104  1    124.41 ? 344 PHE B CB  1 -0.284 0.801  0.043  
ATOM   5736  C  CG  . PHE B 1 355 ? -30.927 88.888  17.083  1    129.29 ? 344 PHE B CG  1 -0.283 0.815  0.043  
ATOM   5737  C  CD1 . PHE B 1 355 ? -31.542 89.601  16.06   1    126.88 ? 344 PHE B CD1 1 -0.289 0.821  0.04   
ATOM   5738  C  CD2 . PHE B 1 355 ? -30.247 89.593  18.08   1    129.35 ? 344 PHE B CD2 1 -0.277 0.821  0.045  
ATOM   5739  C  CE1 . PHE B 1 355 ? -31.488 90.983  16.025  1    125.3  ? 344 PHE B CE1 1 -0.289 0.834  0.04   
ATOM   5740  C  CE2 . PHE B 1 355 ? -30.187 90.985  18.059  1    126.72 ? 344 PHE B CE2 1 -0.277 0.834  0.045  
ATOM   5741  C  CZ  . PHE B 1 355 ? -30.811 91.68   17.027  1    131.91 ? 344 PHE B CZ  1 -0.282 0.84   0.043  
ATOM   5742  N  N   . VAL B 1 356 ? -27.647 87.253  15.721  1    115.63 ? 345 VAL B N   1 -0.253 0.8    0.039  
ATOM   5743  C  CA  . VAL B 1 356 ? -26.224 87.438  15.968  1    111.11 ? 345 VAL B CA  1 -0.24  0.801  0.04   
ATOM   5744  C  C   . VAL B 1 356 ? -25.852 88.86   15.57   1    120    ? 345 VAL B C   1 -0.237 0.814  0.039  
ATOM   5745  O  O   . VAL B 1 356 ? -26.345 89.373  14.557  1    126.22 ? 345 VAL B O   1 -0.241 0.819  0.036  
ATOM   5746  C  CB  . VAL B 1 356 ? -25.39  86.41   15.168  1    106.25 ? 345 VAL B CB  1 -0.233 0.792  0.038  
ATOM   5747  C  CG1 . VAL B 1 356 ? -24.002 86.264  15.738  1    99.42  ? 345 VAL B CG1 1 -0.22  0.791  0.039  
ATOM   5748  C  CG2 . VAL B 1 356 ? -26.114 85.063  15.069  1    105.16 ? 345 VAL B CG2 1 -0.239 0.78   0.038  
ATOM   5749  N  N   . ASN B 1 357 ? -25.002 89.508  16.375  1    124.09 ? 346 ASN B N   1 -0.229 0.82   0.041  
ATOM   5750  C  CA  . ASN B 1 357 ? -24.398 90.799  16.014  1    124.51 ? 346 ASN B CA  1 -0.224 0.832  0.04   
ATOM   5751  C  C   . ASN B 1 357 ? -25.461 91.886  15.761  1    130.47 ? 346 ASN B C   1 -0.233 0.842  0.039  
ATOM   5752  O  O   . ASN B 1 357 ? -25.289 92.766  14.907  1    130.03 ? 346 ASN B O   1 -0.232 0.85   0.037  
ATOM   5753  C  CB  . ASN B 1 357 ? -23.469 90.608  14.801  1    124.79 ? 346 ASN B CB  1 -0.215 0.83   0.037  
ATOM   5754  C  CG  . ASN B 1 357 ? -22.698 91.871  14.411  1    136.72 ? 346 ASN B CG  1 -0.208 0.842  0.036  
ATOM   5755  O  OD1 . ASN B 1 357 ? -22.626 92.84   15.169  1    136.12 ? 346 ASN B OD1 1 -0.207 0.851  0.038  
ATOM   5756  N  ND2 . ASN B 1 357 ? -22.121 91.859  13.205  1    143.12 ? 346 ASN B ND2 1 -0.203 0.842  0.033  
ATOM   5757  N  N   . GLY B 1 358 ? -26.574 91.836  16.492  1    126.16 ? 347 GLY B N   1 -0.244 0.842  0.041  
ATOM   5758  C  CA  . GLY B 1 358 ? -27.668 92.783  16.279  1    122.71 ? 347 GLY B CA  1 -0.254 0.85   0.041  
ATOM   5759  C  C   . GLY B 1 358 ? -28.352 92.732  14.922  1    134.04 ? 347 GLY B C   1 -0.26  0.85   0.037  
ATOM   5760  O  O   . GLY B 1 358 ? -28.762 93.781  14.401  1    131.88 ? 347 GLY B O   1 -0.264 0.859  0.036  
ATOM   5761  N  N   . ARG B 1 359 ? -28.495 91.536  14.338  1    131.64 ? 348 ARG B N   1 -0.261 0.839  0.036  
ATOM   5762  C  CA  . ARG B 1 359 ? -29.202 91.338  13.075  1    126.89 ? 348 ARG B CA  1 -0.268 0.837  0.033  
ATOM   5763  C  C   . ARG B 1 359 ? -29.469 89.848  12.897  1    129.03 ? 348 ARG B C   1 -0.27  0.823  0.032  
ATOM   5764  O  O   . ARG B 1 359 ? -28.603 89.028  13.207  1    127.44 ? 348 ARG B O   1 -0.262 0.816  0.033  
ATOM   5765  C  CB  . ARG B 1 359 ? -28.395 91.878  11.886  1    130.45 ? 348 ARG B CB  1 -0.26  0.842  0.03   
ATOM   5766  C  CG  . ARG B 1 359 ? -29.068 91.692  10.515  1    138.96 ? 348 ARG B CG  1 -0.266 0.84   0.026  
ATOM   5767  C  CD  . ARG B 1 359 ? -28.36  92.487  9.407   1    136.18 ? 348 ARG B CD  1 -0.26  0.848  0.023  
ATOM   5768  N  NE  . ARG B 1 359 ? -27.024 91.977  9.111   1    137.87 ? 348 ARG B NE  1 -0.248 0.843  0.023  
ATOM   5769  C  CZ  . ARG B 1 359 ? -26.081 92.66   8.471   1    142.04 ? 348 ARG B CZ  1 -0.239 0.849  0.021  
ATOM   5770  N  NH1 . ARG B 1 359 ? -26.284 93.902  8.06    1    142.3  ? 348 ARG B NH1 1 -0.241 0.861  0.02   
ATOM   5771  N  NH2 . ARG B 1 359 ? -24.901 92.084  8.242   1    133.99 ? 348 ARG B NH2 1 -0.228 0.844  0.021  
ATOM   5772  N  N   . MET B 1 360 ? -30.664 89.502  12.403  1    125.24 ? 349 MET B N   1 -0.281 0.82   0.031  
ATOM   5773  C  CA  . MET B 1 360 ? -31.001 88.097  12.194  1    119.65 ? 349 MET B CA  1 -0.284 0.807  0.03   
ATOM   5774  C  C   . MET B 1 360 ? -30.112 87.497  11.109  1    118.17 ? 349 MET B C   1 -0.276 0.802  0.028  
ATOM   5775  O  O   . MET B 1 360 ? -30.012 88.035  10.004  1    121.82 ? 349 MET B O   1 -0.275 0.807  0.025  
ATOM   5776  C  CB  . MET B 1 360 ? -32.475 87.942  11.824  1    118.46 ? 349 MET B CB  1 -0.298 0.806  0.03   
ATOM   5777  C  CG  . MET B 1 360 ? -33.431 87.984  13.014  1    125.01 ? 349 MET B CG  1 -0.306 0.806  0.032  
ATOM   5778  S  SD  . MET B 1 360 ? -33.048 86.777  14.319  1    129.06 ? 349 MET B SD  1 -0.303 0.795  0.036  
ATOM   5779  C  CE  . MET B 1 360 ? -34.671 86.116  14.721  1    118.45 ? 349 MET B CE  1 -0.318 0.789  0.037  
ATOM   5780  N  N   . MET B 1 361 ? -29.455 86.39   11.435  1    114.31 ? 350 MET B N   1 -0.27  0.792  0.029  
ATOM   5781  C  CA  . MET B 1 361 ? -28.537 85.729  10.518  1    112.77 ? 350 MET B CA  1 -0.262 0.786  0.026  
ATOM   5782  C  C   . MET B 1 361 ? -29.302 85.041  9.385   1    117.12 ? 350 MET B C   1 -0.269 0.779  0.023  
ATOM   5783  O  O   . MET B 1 361 ? -30.416 84.541  9.567   1    111.92 ? 350 MET B O   1 -0.279 0.775  0.024  
ATOM   5784  C  CB  . MET B 1 361 ? -27.674 84.731  11.302  1    112.88 ? 350 MET B CB  1 -0.254 0.776  0.028  
ATOM   5785  C  CG  . MET B 1 361 ? -27.027 83.604  10.524  1    116.27 ? 350 MET B CG  1 -0.248 0.766  0.026  
ATOM   5786  S  SD  . MET B 1 361 ? -25.653 82.817  11.416  1    121.07 ? 350 MET B SD  1 -0.235 0.759  0.029  
ATOM   5787  C  CE  . MET B 1 361 ? -26.52  81.85   12.658  1    114.85 ? 350 MET B CE  1 -0.243 0.75   0.032  
ATOM   5788  N  N   . GLY B 1 362 ? -28.693 85.045  8.193   1    122.19 ? 351 GLY B N   1 -0.263 0.779  0.02   
ATOM   5789  C  CA  . GLY B 1 362 ? -29.298 84.504  6.998   1    123.88 ? 351 GLY B CA  1 -0.268 0.774  0.017  
ATOM   5790  C  C   . GLY B 1 362 ? -28.674 83.19   6.556   1    124.25 ? 351 GLY B C   1 -0.263 0.762  0.016  
ATOM   5791  O  O   . GLY B 1 362 ? -27.854 82.594  7.259   1    120.46 ? 351 GLY B O   1 -0.255 0.757  0.018  
ATOM   5792  N  N   . LYS B 1 363 ? -29.073 82.745  5.349   1    122.5  ? 352 LYS B N   1 -0.266 0.758  0.013  
ATOM   5793  C  CA  . LYS B 1 363 ? -28.668 81.418  4.878   1    119.01 ? 352 LYS B CA  1 -0.263 0.746  0.012  
ATOM   5794  C  C   . LYS B 1 363 ? -27.158 81.326  4.714   1    117.2  ? 352 LYS B C   1 -0.249 0.745  0.012  
ATOM   5795  O  O   . LYS B 1 363 ? -26.547 80.306  5.057   1    118.43 ? 352 LYS B O   1 -0.243 0.736  0.013  
ATOM   5796  C  CB  . LYS B 1 363 ? -29.357 81.074  3.555   1    116.86 ? 352 LYS B CB  1 -0.269 0.743  0.009  
ATOM   5797  C  CG  . LYS B 1 363 ? -29.517 79.546  3.278   1    123.77 ? 352 LYS B CG  1 -0.27  0.729  0.008  
ATOM   5798  C  CD  . LYS B 1 363 ? -28.216 78.809  2.84    1    128.1  ? 352 LYS B CD  1 -0.259 0.722  0.007  
ATOM   5799  C  CE  . LYS B 1 363 ? -28.196 77.35   3.365   1    129.43 ? 352 LYS B CE  1 -0.258 0.709  0.008  
ATOM   5800  N  NZ  . LYS B 1 363 ? -26.868 76.654  3.292   1    126.69 ? 352 LYS B NZ  1 -0.246 0.702  0.008  
ATOM   5801  N  N   . THR B 1 364 ? -26.538 82.375  4.186   1    118.92 ? 353 THR B N   1 -0.243 0.755  0.01   
ATOM   5802  C  CA  . THR B 1 364 ? -25.119 82.287  3.877   1    123.76 ? 353 THR B CA  1 -0.23  0.754  0.01   
ATOM   5803  C  C   . THR B 1 364 ? -24.306 82.074  5.144   1    119.25 ? 353 THR B C   1 -0.223 0.752  0.013  
ATOM   5804  O  O   . THR B 1 364 ? -23.523 81.122  5.237   1    120.64 ? 353 THR B O   1 -0.216 0.743  0.013  
ATOM   5805  C  CB  . THR B 1 364 ? -24.669 83.536  3.124   1    125.61 ? 353 THR B CB  1 -0.226 0.766  0.008  
ATOM   5806  O  OG1 . THR B 1 364 ? -25.56  83.747  2.02    1    123.04 ? 353 THR B OG1 1 -0.234 0.767  0.005  
ATOM   5807  C  CG2 . THR B 1 364 ? -23.237 83.347  2.595   1    116.05 ? 353 THR B CG2 1 -0.213 0.764  0.006  
ATOM   5808  N  N   . ALA B 1 365 ? -24.511 82.926  6.149   1    119.72 ? 354 ALA B N   1 -0.225 0.76   0.015  
ATOM   5809  C  CA  . ALA B 1 365 ? -23.846 82.715  7.43    1    121.51 ? 354 ALA B CA  1 -0.219 0.758  0.019  
ATOM   5810  C  C   . ALA B 1 365 ? -24.295 81.411  8.089   1    115.27 ? 354 ALA B C   1 -0.223 0.746  0.02   
ATOM   5811  O  O   . ALA B 1 365 ? -23.468 80.677  8.644   1    116.06 ? 354 ALA B O   1 -0.215 0.739  0.022  
ATOM   5812  C  CB  . ALA B 1 365 ? -24.102 83.903  8.359   1    123.52 ? 354 ALA B CB  1 -0.221 0.769  0.021  
ATOM   5813  N  N   . ALA B 1 366 ? -25.595 81.099  8.021   1    110.04 ? 355 ALA B N   1 -0.235 0.743  0.02   
ATOM   5814  C  CA  . ALA B 1 366 ? -26.131 79.965  8.77    1    112.75 ? 355 ALA B CA  1 -0.239 0.733  0.022  
ATOM   5815  C  C   . ALA B 1 366 ? -25.411 78.665  8.428   1    116.37 ? 355 ALA B C   1 -0.233 0.721  0.021  
ATOM   5816  O  O   . ALA B 1 366 ? -25.126 77.858  9.321   1    119.04 ? 355 ALA B O   1 -0.23  0.714  0.023  
ATOM   5817  C  CB  . ALA B 1 366 ? -27.636 79.82   8.529   1    112.72 ? 355 ALA B CB  1 -0.253 0.731  0.021  
ATOM   5818  N  N   . HIS B 1 367 ? -25.095 78.442  7.15    1    116.17 ? 356 HIS B N   1 -0.23  0.719  0.018  
ATOM   5819  C  CA  . HIS B 1 367 ? -24.46  77.179  6.785   1    121.28 ? 356 HIS B CA  1 -0.224 0.707  0.017  
ATOM   5820  C  C   . HIS B 1 367 ? -23.04  77.092  7.317   1    122.53 ? 356 HIS B C   1 -0.211 0.706  0.018  
ATOM   5821  O  O   . HIS B 1 367 ? -22.543 75.989  7.578   1    123.78 ? 356 HIS B O   1 -0.207 0.696  0.019  
ATOM   5822  C  CB  . HIS B 1 367 ? -24.449 76.992  5.268   1    131.88 ? 356 HIS B CB  1 -0.224 0.706  0.013  
ATOM   5823  C  CG  . HIS B 1 367 ? -23.794 75.718  4.812   1    135.35 ? 356 HIS B CG  1 -0.218 0.694  0.012  
ATOM   5824  N  ND1 . HIS B 1 367 ? -22.433 75.501  4.9     1    138.29 ? 356 HIS B ND1 1 -0.206 0.692  0.012  
ATOM   5825  C  CD2 . HIS B 1 367 ? -24.314 74.603  4.245   1    137.84 ? 356 HIS B CD2 1 -0.223 0.684  0.011  
ATOM   5826  C  CE1 . HIS B 1 367 ? -22.145 74.306  4.414   1    139.77 ? 356 HIS B CE1 1 -0.203 0.681  0.011  
ATOM   5827  N  NE2 . HIS B 1 367 ? -23.269 73.741  4.009   1    141.95 ? 356 HIS B NE2 1 -0.213 0.676  0.01   
ATOM   5828  N  N   . GLN B 1 368 ? -22.361 78.226  7.459   1    121.66 ? 357 GLN B N   1 -0.205 0.717  0.019  
ATOM   5829  C  CA  . GLN B 1 368 ? -21.004 78.159  7.976   1    124.15 ? 357 GLN B CA  1 -0.192 0.716  0.02   
ATOM   5830  C  C   . GLN B 1 368 ? -20.967 78.003  9.479   1    118.43 ? 357 GLN B C   1 -0.192 0.715  0.024  
ATOM   5831  O  O   . GLN B 1 368 ? -19.986 77.46   9.994   1    125.16 ? 357 GLN B O   1 -0.183 0.71   0.025  
ATOM   5832  C  CB  . GLN B 1 368 ? -20.201 79.394  7.567   1    121.52 ? 357 GLN B CB  1 -0.185 0.728  0.019  
ATOM   5833  C  CG  . GLN B 1 368 ? -19.941 79.463  6.076   1    131.18 ? 357 GLN B CG  1 -0.183 0.728  0.015  
ATOM   5834  C  CD  . GLN B 1 368 ? -19.932 78.083  5.412   1    137.76 ? 357 GLN B CD  1 -0.183 0.716  0.014  
ATOM   5835  O  OE1 . GLN B 1 368 ? -20.971 77.602  4.943   1    138.96 ? 357 GLN B OE1 1 -0.192 0.711  0.012  
ATOM   5836  N  NE2 . GLN B 1 368 ? -18.758 77.444  5.365   1    139.53 ? 357 GLN B NE2 1 -0.172 0.71   0.013  
ATOM   5837  N  N   . PHE B 1 369 ? -22.024 78.435  10.182  1    115.8  ? 358 PHE B N   1 -0.202 0.719  0.025  
ATOM   5838  C  CA  . PHE B 1 369 ? -22.014 78.57   11.638  1    115.54 ? 358 PHE B CA  1 -0.202 0.72   0.029  
ATOM   5839  C  C   . PHE B 1 369 ? -23.002 77.672  12.374  1    108.74 ? 358 PHE B C   1 -0.211 0.712  0.031  
ATOM   5840  O  O   . PHE B 1 369 ? -23.062 77.733  13.602  1    107.24 ? 358 PHE B O   1 -0.211 0.712  0.034  
ATOM   5841  C  CB  . PHE B 1 369 ? -22.299 80.024  12.034  1    110.65 ? 358 PHE B CB  1 -0.204 0.733  0.03   
ATOM   5842  C  CG  . PHE B 1 369 ? -21.188 80.967  11.7    1    111.03 ? 358 PHE B CG  1 -0.194 0.742  0.029  
ATOM   5843  C  CD1 . PHE B 1 369 ? -19.864 80.589  11.902  1    107.46 ? 358 PHE B CD1 1 -0.182 0.739  0.03   
ATOM   5844  C  CD2 . PHE B 1 369 ? -21.461 82.226  11.176  1    109.42 ? 358 PHE B CD2 1 -0.197 0.754  0.028  
ATOM   5845  C  CE1 . PHE B 1 369 ? -18.835 81.449  11.602  1    109.14 ? 358 PHE B CE1 1 -0.173 0.746  0.029  
ATOM   5846  C  CE2 . PHE B 1 369 ? -20.436 83.092  10.869  1    108.2  ? 358 PHE B CE2 1 -0.187 0.761  0.027  
ATOM   5847  C  CZ  . PHE B 1 369 ? -19.118 82.704  11.083  1    110.45 ? 358 PHE B CZ  1 -0.175 0.758  0.028  
ATOM   5848  N  N   . ARG B 1 370 ? -23.796 76.868  11.67   1    108.43 ? 359 ARG B N   1 -0.218 0.704  0.029  
ATOM   5849  C  CA  . ARG B 1 370 ? -24.765 76.001  12.323  1    100.88 ? 359 ARG B CA  1 -0.227 0.696  0.031  
ATOM   5850  C  C   . ARG B 1 370 ? -24.717 74.598  11.737  1    101.82 ? 359 ARG B C   1 -0.227 0.684  0.029  
ATOM   5851  O  O   . ARG B 1 370 ? -23.763 74.258  11.027  1    107.51 ? 359 ARG B O   1 -0.218 0.681  0.028  
ATOM   5852  C  CB  . ARG B 1 370 ? -26.178 76.573  12.209  1    103.51 ? 359 ARG B CB  1 -0.24  0.702  0.03   
ATOM   5853  C  CG  . ARG B 1 370 ? -26.372 77.906  12.927  1    104.18 ? 359 ARG B CG  1 -0.242 0.714  0.032  
ATOM   5854  C  CD  . ARG B 1 370 ? -26.744 77.707  14.379  1    105.66 ? 359 ARG B CD  1 -0.245 0.712  0.036  
ATOM   5855  N  NE  . ARG B 1 370 ? -26.92  78.977  15.066  1    102.65 ? 359 ARG B NE  1 -0.247 0.724  0.038  
ATOM   5856  C  CZ  . ARG B 1 370 ? -25.914 79.753  15.447  1    104.62 ? 359 ARG B CZ  1 -0.237 0.731  0.039  
ATOM   5857  N  NH1 . ARG B 1 370 ? -24.654 79.421  15.207  1    99.79  ? 359 ARG B NH1 1 -0.226 0.728  0.038  
ATOM   5858  N  NH2 . ARG B 1 370 ? -26.178 80.887  16.092  1    106.86 ? 359 ARG B NH2 1 -0.24  0.741  0.04   
ATOM   5859  N  N   . PHE B 1 371 ? -25.72  73.787  12.032  1    97.26  ? 360 PHE B N   1 -0.236 0.676  0.03   
ATOM   5860  C  CA  . PHE B 1 371 ? -25.73  72.389  11.641  1    98.1   ? 360 PHE B CA  1 -0.236 0.663  0.029  
ATOM   5861  C  C   . PHE B 1 371 ? -26.931 72.11   10.748  1    99.52  ? 360 PHE B C   1 -0.247 0.661  0.027  
ATOM   5862  O  O   . PHE B 1 371 ? -27.943 72.817  10.799  1    99.37  ? 360 PHE B O   1 -0.256 0.667  0.027  
ATOM   5863  C  CB  . PHE B 1 371 ? -25.78  71.438  12.87   1    100.81 ? 360 PHE B CB  1 -0.236 0.655  0.032  
ATOM   5864  C  CG  . PHE B 1 371 ? -24.632 71.604  13.842  1    97.26  ? 360 PHE B CG  1 -0.226 0.656  0.035  
ATOM   5865  C  CD1 . PHE B 1 371 ? -23.335 71.807  13.39   1    96.66  ? 360 PHE B CD1 1 -0.214 0.658  0.033  
ATOM   5866  C  CD2 . PHE B 1 371 ? -24.867 71.571  15.218  1    105.42 ? 360 PHE B CD2 1 -0.228 0.656  0.038  
ATOM   5867  C  CE1 . PHE B 1 371 ? -22.291 71.969  14.283  1    100.9  ? 360 PHE B CE1 1 -0.204 0.66   0.036  
ATOM   5868  C  CE2 . PHE B 1 371 ? -23.833 71.727  16.129  1    102.45 ? 360 PHE B CE2 1 -0.218 0.657  0.04   
ATOM   5869  C  CZ  . PHE B 1 371 ? -22.537 71.926  15.659  1    107.19 ? 360 PHE B CZ  1 -0.207 0.659  0.039  
ATOM   5870  N  N   . ASN B 1 372 ? -26.804 71.066  9.932   1    98.35  ? 361 ASN B N   1 -0.246 0.651  0.025  
ATOM   5871  C  CA  . ASN B 1 372 ? -27.865 70.613  9.046   1    107.75 ? 361 ASN B CA  1 -0.255 0.647  0.023  
ATOM   5872  C  C   . ASN B 1 372 ? -28.089 69.125  9.27    1    103.13 ? 361 ASN B C   1 -0.257 0.633  0.023  
ATOM   5873  O  O   . ASN B 1 372 ? -27.331 68.462  9.987   1    100.95 ? 361 ASN B O   1 -0.25  0.627  0.025  
ATOM   5874  C  CB  . ASN B 1 372 ? -27.555 70.897  7.55    1    98.97  ? 361 ASN B CB  1 -0.253 0.65   0.019  
ATOM   5875  C  CG  . ASN B 1 372 ? -26.403 70.052  7.001   1    95.62  ? 361 ASN B CG  1 -0.242 0.642  0.017  
ATOM   5876  O  OD1 . ASN B 1 372 ? -25.971 69.092  7.606   1    101.64 ? 361 ASN B OD1 1 -0.238 0.633  0.019  
ATOM   5877  N  ND2 . ASN B 1 372 ? -25.912 70.419  5.849   1    109.13 ? 361 ASN B ND2 1 -0.237 0.645  0.015  
ATOM   5878  N  N   . ASP B 1 373 ? -29.105 68.587  8.585   1    102.9  ? 362 ASP B N   1 -0.267 0.629  0.021  
ATOM   5879  C  CA  . ASP B 1 373 ? -29.441 67.181  8.767   1    100.51 ? 362 ASP B CA  1 -0.27  0.616  0.022  
ATOM   5880  C  C   . ASP B 1 373 ? -28.286 66.272  8.397   1    101.11 ? 362 ASP B C   1 -0.259 0.607  0.021  
ATOM   5881  O  O   . ASP B 1 373 ? -28.192 65.157  8.924   1    98.04  ? 362 ASP B O   1 -0.258 0.597  0.022  
ATOM   5882  C  CB  . ASP B 1 373 ? -30.685 66.847  7.963   1    99.18  ? 362 ASP B CB  1 -0.281 0.613  0.02   
ATOM   5883  C  CG  . ASP B 1 373 ? -31.832 67.754  8.313   1    106.65 ? 362 ASP B CG  1 -0.292 0.621  0.021  
ATOM   5884  O  OD1 . ASP B 1 373 ? -31.572 68.751  9.026   1    105.71 ? 362 ASP B OD1 1 -0.289 0.63   0.023  
ATOM   5885  O  OD2 . ASP B 1 373 ? -32.979 67.485  7.891   1    108.35 ? 362 ASP B OD2 1 -0.302 0.618  0.02   
ATOM   5886  N  N   . GLY B 1 374 ? -27.383 66.74   7.539   1    105.1  ? 363 GLY B N   1 -0.251 0.612  0.019  
ATOM   5887  C  CA  . GLY B 1 374 ? -26.204 65.947  7.242   1    108.65 ? 363 GLY B CA  1 -0.24  0.604  0.018  
ATOM   5888  C  C   . GLY B 1 374 ? -25.343 65.747  8.47    1    100.59 ? 363 GLY B C   1 -0.232 0.603  0.021  
ATOM   5889  O  O   . GLY B 1 374 ? -24.975 64.62   8.812   1    101.73 ? 363 GLY B O   1 -0.229 0.592  0.022  
ATOM   5890  N  N   . ASP B 1 375 ? -25.035 66.842  9.166   1    101.87 ? 364 ASP B N   1 -0.229 0.613  0.023  
ATOM   5891  C  CA  . ASP B 1 375 ? -24.227 66.748  10.382  1    105.76 ? 364 ASP B CA  1 -0.222 0.612  0.026  
ATOM   5892  C  C   . ASP B 1 375 ? -24.943 65.938  11.47   1    102.02 ? 364 ASP B C   1 -0.229 0.604  0.029  
ATOM   5893  O  O   . ASP B 1 375 ? -24.371 65      12.045  1    98.63  ? 364 ASP B O   1 -0.223 0.596  0.03   
ATOM   5894  C  CB  . ASP B 1 375 ? -23.901 68.148  10.916  1    104.66 ? 364 ASP B CB  1 -0.219 0.625  0.027  
ATOM   5895  C  CG  . ASP B 1 375 ? -23.558 69.173  9.828   1    101.63 ? 364 ASP B CG  1 -0.216 0.634  0.025  
ATOM   5896  O  OD1 . ASP B 1 375 ? -22.485 69.056  9.182   1    104.85 ? 364 ASP B OD1 1 -0.206 0.633  0.023  
ATOM   5897  O  OD2 . ASP B 1 375 ? -24.347 70.139  9.684   1    94.3   ? 364 ASP B OD2 1 -0.223 0.643  0.024  
ATOM   5898  N  N   . LEU B 1 376 ? -26.186 66.322  11.792  1    100.16 ? 365 LEU B N   1 -0.24  0.608  0.029  
ATOM   5899  C  CA  . LEU B 1 376 ? -26.948 65.66   12.85   1    97.94  ? 365 LEU B CA  1 -0.247 0.602  0.032  
ATOM   5900  C  C   . LEU B 1 376 ? -27.041 64.161  12.599  1    103.51 ? 365 LEU B C   1 -0.248 0.588  0.031  
ATOM   5901  O  O   . LEU B 1 376 ? -26.779 63.353  13.5    1    100.92 ? 365 LEU B O   1 -0.245 0.581  0.034  
ATOM   5902  C  CB  . LEU B 1 376 ? -28.354 66.27   12.952  1    99.77  ? 365 LEU B CB  1 -0.26  0.607  0.032  
ATOM   5903  C  CG  . LEU B 1 376 ? -28.643 67.563  13.732  1    95.76  ? 365 LEU B CG  1 -0.262 0.619  0.034  
ATOM   5904  C  CD1 . LEU B 1 376 ? -28.882 67.219  15.176  1    111.57 ? 365 LEU B CD1 1 -0.265 0.616  0.038  
ATOM   5905  C  CD2 . LEU B 1 376 ? -27.513 68.564  13.649  1    87.65  ? 365 LEU B CD2 1 -0.252 0.628  0.034  
ATOM   5906  N  N   . GLY B 1 377 ? -27.408 63.771  11.369  1    105.33 ? 366 GLY B N   1 -0.251 0.584  0.028  
ATOM   5907  C  CA  . GLY B 1 377 ? -27.547 62.357  11.052  1    89.81  ? 366 GLY B CA  1 -0.252 0.571  0.028  
ATOM   5908  C  C   . GLY B 1 377 ? -26.24  61.602  11.189  1    96.13  ? 366 GLY B C   1 -0.24  0.565  0.028  
ATOM   5909  O  O   . GLY B 1 377 ? -26.216 60.469  11.67   1    98.29  ? 366 GLY B O   1 -0.24  0.554  0.029  
ATOM   5910  N  N   . TYR B 1 378 ? -25.131 62.221  10.775  1    100.62 ? 367 TYR B N   1 -0.23  0.57   0.027  
ATOM   5911  C  CA  . TYR B 1 378 ? -23.838 61.549  10.863  1    102.72 ? 367 TYR B CA  1 -0.218 0.564  0.027  
ATOM   5912  C  C   . TYR B 1 378 ? -23.332 61.509  12.3    1    105.46 ? 367 TYR B C   1 -0.214 0.564  0.031  
ATOM   5913  O  O   . TYR B 1 378 ? -22.584 60.593  12.666  1    102.64 ? 367 TYR B O   1 -0.207 0.555  0.032  
ATOM   5914  C  CB  . TYR B 1 378 ? -22.827 62.243  9.945   1    101.36 ? 367 TYR B CB  1 -0.209 0.57   0.025  
ATOM   5915  C  CG  . TYR B 1 378 ? -21.465 61.591  9.914   1    108.9  ? 367 TYR B CG  1 -0.197 0.564  0.025  
ATOM   5916  C  CD1 . TYR B 1 378 ? -21.188 60.562  9.027   1    109.71 ? 367 TYR B CD1 1 -0.194 0.555  0.023  
ATOM   5917  C  CD2 . TYR B 1 378 ? -20.451 62.006  10.772  1    115.12 ? 367 TYR B CD2 1 -0.187 0.568  0.027  
ATOM   5918  C  CE1 . TYR B 1 378 ? -19.936 59.96   8.992   1    114.55 ? 367 TYR B CE1 1 -0.183 0.549  0.022  
ATOM   5919  C  CE2 . TYR B 1 378 ? -19.194 61.407  10.75   1    118.46 ? 367 TYR B CE2 1 -0.176 0.563  0.027  
ATOM   5920  C  CZ  . TYR B 1 378 ? -18.942 60.384  9.853   1    118.82 ? 367 TYR B CZ  1 -0.174 0.553  0.025  
ATOM   5921  O  OH  . TYR B 1 378 ? -17.702 59.785  9.816   1    118    ? 367 TYR B OH  1 -0.162 0.548  0.025  
ATOM   5922  N  N   . PHE B 1 379 ? -23.73  62.491  13.12   1    105.18 ? 368 PHE B N   1 -0.217 0.573  0.033  
ATOM   5923  C  CA  . PHE B 1 379 ? -23.303 62.547  14.519  1    108.97 ? 368 PHE B CA  1 -0.214 0.573  0.036  
ATOM   5924  C  C   . PHE B 1 379 ? -23.945 61.425  15.33   1    105.91 ? 368 PHE B C   1 -0.219 0.563  0.038  
ATOM   5925  O  O   . PHE B 1 379 ? -23.243 60.601  15.931  1    103.73 ? 368 PHE B O   1 -0.213 0.555  0.04   
ATOM   5926  C  CB  . PHE B 1 379 ? -23.643 63.931  15.097  1    109.22 ? 368 PHE B CB  1 -0.217 0.586  0.038  
ATOM   5927  C  CG  . PHE B 1 379 ? -23.325 64.119  16.574  1    109.28 ? 368 PHE B CG  1 -0.214 0.588  0.041  
ATOM   5928  C  CD1 . PHE B 1 379 ? -22.021 64.334  17.008  1    107.66 ? 368 PHE B CD1 1 -0.202 0.59   0.042  
ATOM   5929  C  CD2 . PHE B 1 379 ? -24.351 64.168  17.516  1    107.73 ? 368 PHE B CD2 1 -0.223 0.588  0.044  
ATOM   5930  C  CE1 . PHE B 1 379 ? -21.747 64.54   18.357  1    97.2   ? 368 PHE B CE1 1 -0.199 0.591  0.046  
ATOM   5931  C  CE2 . PHE B 1 379 ? -24.077 64.382  18.862  1    97.93  ? 368 PHE B CE2 1 -0.221 0.59   0.047  
ATOM   5932  C  CZ  . PHE B 1 379 ? -22.78  64.57   19.273  1    97.22  ? 368 PHE B CZ  1 -0.209 0.592  0.048  
ATOM   5933  N  N   . TYR B 1 380 ? -25.283 61.368  15.342  1    103.71 ? 369 TYR B N   1 -0.232 0.562  0.038  
ATOM   5934  C  CA  . TYR B 1 380 ? -25.958 60.32   16.098  1    107.47 ? 369 TYR B CA  1 -0.238 0.553  0.04   
ATOM   5935  C  C   . TYR B 1 380 ? -25.593 58.945  15.557  1    110.16 ? 369 TYR B C   1 -0.235 0.54   0.039  
ATOM   5936  O  O   . TYR B 1 380 ? -25.443 57.99   16.328  1    113.25 ? 369 TYR B O   1 -0.233 0.531  0.041  
ATOM   5937  C  CB  . TYR B 1 380 ? -27.479 60.508  16.082  1    107.11 ? 369 TYR B CB  1 -0.252 0.555  0.04   
ATOM   5938  C  CG  . TYR B 1 380 ? -27.977 61.794  16.713  1    109.08 ? 369 TYR B CG  1 -0.256 0.566  0.042  
ATOM   5939  C  CD1 . TYR B 1 380 ? -27.934 61.996  18.09   1    111.45 ? 369 TYR B CD1 1 -0.256 0.568  0.045  
ATOM   5940  C  CD2 . TYR B 1 380 ? -28.499 62.801  15.926  1    112.26 ? 369 TYR B CD2 1 -0.261 0.576  0.04   
ATOM   5941  C  CE1 . TYR B 1 380 ? -28.397 63.197  18.655  1    114.26 ? 369 TYR B CE1 1 -0.26  0.579  0.047  
ATOM   5942  C  CE2 . TYR B 1 380 ? -28.962 63.985  16.474  1    112.46 ? 369 TYR B CE2 1 -0.265 0.586  0.041  
ATOM   5943  C  CZ  . TYR B 1 380 ? -28.916 64.185  17.825  1    109.69 ? 369 TYR B CZ  1 -0.265 0.588  0.045  
ATOM   5944  O  OH  . TYR B 1 380 ? -29.394 65.39   18.305  1    110.39 ? 369 TYR B OH  1 -0.269 0.599  0.046  
ATOM   5945  N  N   . GLU B 1 381 ? -25.411 58.835  14.237  1    107.45 ? 370 GLU B N   1 -0.233 0.539  0.036  
ATOM   5946  C  CA  . GLU B 1 381 ? -25.071 57.55   13.64   1    103.17 ? 370 GLU B CA  1 -0.23  0.527  0.034  
ATOM   5947  C  C   . GLU B 1 381 ? -23.683 57.079  14.066  1    101.33 ? 370 GLU B C   1 -0.217 0.523  0.035  
ATOM   5948  O  O   . GLU B 1 381 ? -23.492 55.904  14.401  1    105.64 ? 370 GLU B O   1 -0.215 0.512  0.036  
ATOM   5949  C  CB  . GLU B 1 381 ? -25.172 57.634  12.116  1    108.5  ? 370 GLU B CB  1 -0.231 0.528  0.03   
ATOM   5950  C  CG  . GLU B 1 381 ? -24.636 56.397  11.362  1    111    ? 370 GLU B CG  1 -0.226 0.517  0.028  
ATOM   5951  C  CD  . GLU B 1 381 ? -25.338 55.121  11.812  1    115.79 ? 370 GLU B CD  1 -0.232 0.505  0.029  
ATOM   5952  O  OE1 . GLU B 1 381 ? -24.637 54.144  12.186  1    119.96 ? 370 GLU B OE1 1 -0.226 0.496  0.03   
ATOM   5953  O  OE2 . GLU B 1 381 ? -26.584 55.105  11.822  1    120.58 ? 370 GLU B OE2 1 -0.244 0.505  0.03   
ATOM   5954  N  N   . SER B 1 382 ? -22.689 57.971  14.022  1    97.99  ? 371 SER B N   1 -0.208 0.531  0.035  
ATOM   5955  C  CA  . SER B 1 382 ? -21.379 57.64   14.573  1    103.11 ? 371 SER B CA  1 -0.196 0.528  0.036  
ATOM   5956  C  C   . SER B 1 382 ? -21.485 57.261  16.057  1    110.63 ? 371 SER B C   1 -0.197 0.525  0.04   
ATOM   5957  O  O   . SER B 1 382 ? -20.93  56.244  16.495  1    107.2  ? 371 SER B O   1 -0.192 0.515  0.041  
ATOM   5958  C  CB  . SER B 1 382 ? -20.427 58.818  14.376  1    108.55 ? 371 SER B CB  1 -0.187 0.539  0.036  
ATOM   5959  O  OG  . SER B 1 382 ? -20.321 59.197  13.003  1    107.51 ? 371 SER B OG  1 -0.186 0.542  0.032  
ATOM   5960  N  N   . ILE B 1 383 ? -22.232 58.052  16.84   1    108.49 ? 372 ILE B N   1 -0.204 0.532  0.042  
ATOM   5961  C  CA  . ILE B 1 383 ? -22.234 57.885  18.297  1    108.88 ? 372 ILE B CA  1 -0.204 0.53   0.046  
ATOM   5962  C  C   . ILE B 1 383 ? -22.774 56.514  18.689  1    107.52 ? 372 ILE B C   1 -0.209 0.518  0.047  
ATOM   5963  O  O   . ILE B 1 383 ? -22.142 55.782  19.464  1    105.52 ? 372 ILE B O   1 -0.203 0.511  0.049  
ATOM   5964  C  CB  . ILE B 1 383 ? -23.026 59.018  18.976  1    107.2  ? 372 ILE B CB  1 -0.211 0.541  0.047  
ATOM   5965  C  CG1 . ILE B 1 383 ? -22.107 60.196  19.281  1    105.35 ? 372 ILE B CG1 1 -0.203 0.552  0.048  
ATOM   5966  C  CG2 . ILE B 1 383 ? -23.684 58.541  20.272  1    103.57 ? 372 ILE B CG2 1 -0.217 0.536  0.051  
ATOM   5967  C  CD1 . ILE B 1 383 ? -22.834 61.321  19.949  1    112.06 ? 372 ILE B CD1 1 -0.209 0.562  0.05   
ATOM   5968  N  N   . PHE B 1 384 ? -23.95  56.14   18.165  1    104.2  ? 373 PHE B N   1 -0.219 0.514  0.045  
ATOM   5969  C  CA  . PHE B 1 384 ? -24.506 54.837  18.52   1    108.17 ? 373 PHE B CA  1 -0.225 0.503  0.046  
ATOM   5970  C  C   . PHE B 1 384 ? -23.657 53.688  17.977  1    112.38 ? 373 PHE B C   1 -0.217 0.492  0.045  
ATOM   5971  O  O   . PHE B 1 384 ? -23.77  52.556  18.466  1    113.4  ? 373 PHE B O   1 -0.218 0.482  0.046  
ATOM   5972  C  CB  . PHE B 1 384 ? -25.944 54.676  18.019  1    106.46 ? 373 PHE B CB  1 -0.238 0.501  0.045  
ATOM   5973  C  CG  . PHE B 1 384 ? -26.902 55.734  18.502  1    103.35 ? 373 PHE B CG  1 -0.247 0.511  0.046  
ATOM   5974  C  CD1 . PHE B 1 384 ? -26.571 56.61   19.513  1    105.84 ? 373 PHE B CD1 1 -0.244 0.519  0.049  
ATOM   5975  C  CD2 . PHE B 1 384 ? -28.152 55.845  17.917  1    108.57 ? 373 PHE B CD2 1 -0.258 0.512  0.045  
ATOM   5976  C  CE1 . PHE B 1 384 ? -27.474 57.58   19.933  1    108.22 ? 373 PHE B CE1 1 -0.252 0.528  0.05   
ATOM   5977  C  CE2 . PHE B 1 384 ? -29.054 56.802  18.322  1    104.8  ? 373 PHE B CE2 1 -0.266 0.521  0.046  
ATOM   5978  C  CZ  . PHE B 1 384 ? -28.715 57.672  19.338  1    108.07 ? 373 PHE B CZ  1 -0.263 0.529  0.048  
ATOM   5979  N  N   . THR B 1 385 ? -22.808 53.948  16.98   1    110.2  ? 374 THR B N   1 -0.209 0.494  0.042  
ATOM   5980  C  CA  . THR B 1 385 ? -21.9   52.903  16.518  1    115.22 ? 374 THR B CA  1 -0.201 0.485  0.041  
ATOM   5981  C  C   . THR B 1 385 ? -20.814 52.641  17.554  1    112.42 ? 374 THR B C   1 -0.191 0.482  0.044  
ATOM   5982  O  O   . THR B 1 385 ? -20.582 51.488  17.942  1    113.4  ? 374 THR B O   1 -0.189 0.472  0.045  
ATOM   5983  C  CB  . THR B 1 385 ? -21.29  53.268  15.156  1    112.92 ? 374 THR B CB  1 -0.195 0.488  0.038  
ATOM   5984  O  OG1 . THR B 1 385 ? -22.267 53.079  14.12   1    109.28 ? 374 THR B OG1 1 -0.204 0.486  0.035  
ATOM   5985  C  CG2 . THR B 1 385 ? -20.061 52.406  14.867  1    108.39 ? 374 THR B CG2 1 -0.184 0.48   0.037  
ATOM   5986  N  N   . LEU B 1 386 ? -20.153 53.706  18.031  1    110.51 ? 375 LEU B N   1 -0.185 0.492  0.045  
ATOM   5987  C  CA  . LEU B 1 386 ? -19.237 53.576  19.164  1    110.48 ? 375 LEU B CA  1 -0.176 0.491  0.048  
ATOM   5988  C  C   . LEU B 1 386 ? -19.882 52.766  20.282  1    111.35 ? 375 LEU B C   1 -0.182 0.484  0.051  
ATOM   5989  O  O   . LEU B 1 386 ? -19.233 51.914  20.905  1    106.94 ? 375 LEU B O   1 -0.176 0.476  0.052  
ATOM   5990  C  CB  . LEU B 1 386 ? -18.828 54.962  19.68   1    102.92 ? 375 LEU B CB  1 -0.173 0.504  0.049  
ATOM   5991  C  CG  . LEU B 1 386 ? -17.779 55.851  18.999  1    106.08 ? 375 LEU B CG  1 -0.163 0.512  0.047  
ATOM   5992  C  CD1 . LEU B 1 386 ? -16.463 55.104  18.838  1    113.58 ? 375 LEU B CD1 1 -0.151 0.505  0.047  
ATOM   5993  C  CD2 . LEU B 1 386 ? -18.252 56.423  17.669  1    110.33 ? 375 LEU B CD2 1 -0.167 0.517  0.044  
ATOM   5994  N  N   . TYR B 1 387 ? -21.181 52.987  20.503  1    106.36 ? 376 TYR B N   1 -0.194 0.486  0.051  
ATOM   5995  C  CA  . TYR B 1 387 ? -21.913 52.305  21.564  1    111.29 ? 376 TYR B CA  1 -0.201 0.479  0.054  
ATOM   5996  C  C   . TYR B 1 387 ? -21.982 50.804  21.316  1    111.19 ? 376 TYR B C   1 -0.201 0.466  0.053  
ATOM   5997  O  O   . TYR B 1 387 ? -21.453 50.01   22.101  1    116.65 ? 376 TYR B O   1 -0.197 0.458  0.055  
ATOM   5998  C  CB  . TYR B 1 387 ? -23.312 52.913  21.684  1    113.02 ? 376 TYR B CB  1 -0.214 0.485  0.054  
ATOM   5999  C  CG  . TYR B 1 387 ? -24.216 52.271  22.711  1    116.48 ? 376 TYR B CG  1 -0.222 0.479  0.057  
ATOM   6000  C  CD1 . TYR B 1 387 ? -23.75  51.924  23.982  1    118.72 ? 376 TYR B CD1 1 -0.218 0.476  0.06   
ATOM   6001  C  CD2 . TYR B 1 387 ? -25.553 52.05   22.424  1    115.86 ? 376 TYR B CD2 1 -0.234 0.477  0.056  
ATOM   6002  C  CE1 . TYR B 1 387 ? -24.598 51.343  24.924  1    116.95 ? 376 TYR B CE1 1 -0.225 0.471  0.062  
ATOM   6003  C  CE2 . TYR B 1 387 ? -26.4   51.481  23.351  1    118.76 ? 376 TYR B CE2 1 -0.242 0.472  0.058  
ATOM   6004  C  CZ  . TYR B 1 387 ? -25.927 51.129  24.59   1    118.22 ? 376 TYR B CZ  1 -0.238 0.469  0.061  
ATOM   6005  O  OH  . TYR B 1 387 ? -26.806 50.554  25.47   1    122.7  ? 376 TYR B OH  1 -0.246 0.463  0.064  
ATOM   6006  N  N   . ASN B 1 388 ? -22.622 50.393  20.221  1    115.88 ? 377 ASN B N   1 -0.207 0.462  0.05   
ATOM   6007  C  CA  . ASN B 1 388 ? -22.793 48.965  19.972  1    115.13 ? 377 ASN B CA  1 -0.209 0.449  0.05   
ATOM   6008  C  C   . ASN B 1 388 ? -21.456 48.265  19.79   1    107.35 ? 377 ASN B C   1 -0.197 0.442  0.049  
ATOM   6009  O  O   . ASN B 1 388 ? -21.311 47.093  20.156  1    101.08 ? 377 ASN B O   1 -0.195 0.432  0.05   
ATOM   6010  C  CB  . ASN B 1 388 ? -23.684 48.743  18.75   1    109.3  ? 377 ASN B CB  1 -0.217 0.447  0.047  
ATOM   6011  C  CG  . ASN B 1 388 ? -25.116 49.21   18.979  1    116.61 ? 377 ASN B CG  1 -0.23  0.451  0.047  
ATOM   6012  O  OD1 . ASN B 1 388 ? -25.698 49.006  20.059  1    113.37 ? 377 ASN B OD1 1 -0.236 0.449  0.05   
ATOM   6013  N  ND2 . ASN B 1 388 ? -25.695 49.842  17.956  1    116.16 ? 377 ASN B ND2 1 -0.235 0.457  0.045  
ATOM   6014  N  N   . GLU B 1 389 ? -20.461 48.968  19.263  1    110.51 ? 378 GLU B N   1 -0.188 0.449  0.048  
ATOM   6015  C  CA  . GLU B 1 389 ? -19.175 48.324  19.042  1    119.32 ? 378 GLU B CA  1 -0.176 0.443  0.048  
ATOM   6016  C  C   . GLU B 1 389 ? -18.423 48.129  20.349  1    116.38 ? 378 GLU B C   1 -0.169 0.441  0.051  
ATOM   6017  O  O   . GLU B 1 389 ? -17.769 47.095  20.544  1    116.45 ? 378 GLU B O   1 -0.163 0.432  0.051  
ATOM   6018  C  CB  . GLU B 1 389 ? -18.338 49.13   18.051  1    116.34 ? 378 GLU B CB  1 -0.168 0.45   0.045  
ATOM   6019  C  CG  . GLU B 1 389 ? -18.819 49.018  16.631  1    119.97 ? 378 GLU B CG  1 -0.172 0.449  0.042  
ATOM   6020  C  CD  . GLU B 1 389 ? -17.87  49.692  15.661  1    129.41 ? 378 GLU B CD  1 -0.164 0.455  0.039  
ATOM   6021  O  OE1 . GLU B 1 389 ? -16.806 50.171  16.117  1    127.07 ? 378 GLU B OE1 1 -0.154 0.46   0.04   
ATOM   6022  O  OE2 . GLU B 1 389 ? -18.186 49.741  14.45   1    127.82 ? 378 GLU B OE2 1 -0.167 0.456  0.036  
ATOM   6023  N  N   . ASN B 1 390 ? -18.495 49.114  21.25   1    115.72 ? 379 ASN B N   1 -0.169 0.45   0.053  
ATOM   6024  C  CA  . ASN B 1 390 ? -17.893 48.99   22.575  1    117.61 ? 379 ASN B CA  1 -0.164 0.449  0.056  
ATOM   6025  C  C   . ASN B 1 390 ? -18.939 49.056  23.679  1    116.42 ? 379 ASN B C   1 -0.174 0.45   0.059  
ATOM   6026  O  O   . ASN B 1 390 ? -18.932 49.987  24.493  1    115.39 ? 379 ASN B O   1 -0.173 0.458  0.061  
ATOM   6027  C  CB  . ASN B 1 390 ? -16.858 50.085  22.807  1    118.02 ? 379 ASN B CB  1 -0.154 0.459  0.057  
ATOM   6028  C  CG  . ASN B 1 390 ? -15.847 50.146  21.725  1    120.59 ? 379 ASN B CG  1 -0.145 0.46   0.054  
ATOM   6029  O  OD1 . ASN B 1 390 ? -15.788 51.119  20.975  1    122.26 ? 379 ASN B OD1 1 -0.145 0.468  0.052  
ATOM   6030  N  ND2 . ASN B 1 390 ? -15.043 49.096  21.612  1    129.57 ? 379 ASN B ND2 1 -0.138 0.45   0.054  
ATOM   6031  N  N   . LYS B 1 391 ? -19.844 48.084  23.725  1    109.84 ? 380 LYS B N   1 -0.182 0.441  0.059  
ATOM   6032  C  CA  . LYS B 1 391 ? -20.687 48.004  24.906  1    116.33 ? 380 LYS B CA  1 -0.19  0.44   0.062  
ATOM   6033  C  C   . LYS B 1 391 ? -19.905 47.562  26.148  1    123.5  ? 380 LYS B C   1 -0.182 0.436  0.065  
ATOM   6034  O  O   . LYS B 1 391 ? -20.483 47.495  27.244  1    119    ? 380 LYS B O   1 -0.188 0.435  0.068  
ATOM   6035  C  CB  . LYS B 1 391 ? -21.856 47.06   24.636  1    110.6  ? 380 LYS B CB  1 -0.2   0.431  0.062  
ATOM   6036  C  CG  . LYS B 1 391 ? -22.913 47.633  23.729  1    110.75 ? 380 LYS B CG  1 -0.21  0.437  0.059  
ATOM   6037  C  CD  . LYS B 1 391 ? -24.221 46.887  23.925  1    117.18 ? 380 LYS B CD  1 -0.222 0.43   0.06   
ATOM   6038  C  CE  . LYS B 1 391 ? -25.369 47.527  23.153  1    117.77 ? 380 LYS B CE  1 -0.232 0.436  0.058  
ATOM   6039  N  NZ  . LYS B 1 391 ? -26.697 47.068  23.67   1    120.55 ? 380 LYS B NZ  1 -0.245 0.431  0.059  
ATOM   6040  N  N   . ASP B 1 392 ? -18.607 47.26   25.992  1    123.95 ? 381 ASP B N   1 -0.171 0.433  0.065  
ATOM   6041  C  CA  . ASP B 1 392 ? -17.752 46.907  27.12   1    125.17 ? 381 ASP B CA  1 -0.163 0.43   0.068  
ATOM   6042  C  C   . ASP B 1 392 ? -17.268 48.138  27.877  1    123.25 ? 381 ASP B C   1 -0.158 0.441  0.07   
ATOM   6043  O  O   . ASP B 1 392 ? -16.96  48.04   29.069  1    111.16 ? 381 ASP B O   1 -0.155 0.44   0.073  
ATOM   6044  C  CB  . ASP B 1 392 ? -16.554 46.06   26.646  1    127.7  ? 381 ASP B CB  1 -0.152 0.422  0.067  
ATOM   6045  C  CG  . ASP B 1 392 ? -15.938 46.556  25.325  1    129.6  ? 381 ASP B CG  1 -0.146 0.427  0.063  
ATOM   6046  O  OD1 . ASP B 1 392 ? -16.671 46.641  24.311  1    127.37 ? 381 ASP B OD1 1 -0.153 0.427  0.061  
ATOM   6047  O  OD2 . ASP B 1 392 ? -14.709 46.837  25.295  1    131.42 ? 381 ASP B OD2 1 -0.135 0.429  0.063  
ATOM   6048  N  N   . CYS B 1 393 ? -17.189 49.291  27.208  1    124.48 ? 382 CYS B N   1 -0.158 0.452  0.068  
ATOM   6049  C  CA  . CYS B 1 393 ? -16.83  50.552  27.851  1    122.52 ? 382 CYS B CA  1 -0.154 0.463  0.07   
ATOM   6050  C  C   . CYS B 1 393 ? -18.026 51.429  28.146  1    114.17 ? 382 CYS B C   1 -0.165 0.471  0.07   
ATOM   6051  O  O   . CYS B 1 393 ? -18.073 52.064  29.19   1    116.79 ? 382 CYS B O   1 -0.166 0.477  0.073  
ATOM   6052  C  CB  . CYS B 1 393 ? -15.873 51.37   26.982  1    127.99 ? 382 CYS B CB  1 -0.145 0.471  0.067  
ATOM   6053  S  SG  . CYS B 1 393 ? -14.317 50.602  26.598  1    141.93 ? 382 CYS B SG  1 -0.131 0.464  0.066  
ATOM   6054  N  N   . VAL B 1 394 ? -18.968 51.535  27.214  1    118.39 ? 383 VAL B N   1 -0.174 0.472  0.068  
ATOM   6055  C  CA  . VAL B 1 394 ? -20.1   52.432  27.395  1    116.57 ? 383 VAL B CA  1 -0.184 0.48   0.068  
ATOM   6056  C  C   . VAL B 1 394 ? -21.088 51.715  28.304  1    117.04 ? 383 VAL B C   1 -0.193 0.474  0.071  
ATOM   6057  O  O   . VAL B 1 394 ? -21.746 50.753  27.908  1    119.57 ? 383 VAL B O   1 -0.199 0.465  0.07   
ATOM   6058  C  CB  . VAL B 1 394 ? -20.742 52.849  26.073  1    122.8  ? 383 VAL B CB  1 -0.19  0.484  0.065  
ATOM   6059  C  CG1 . VAL B 1 394 ? -22.056 53.565  26.353  1    125.13 ? 383 VAL B CG1 1 -0.202 0.491  0.066  
ATOM   6060  C  CG2 . VAL B 1 394 ? -19.808 53.75   25.272  1    112.13 ? 383 VAL B CG2 1 -0.182 0.493  0.063  
ATOM   6061  N  N   . ASP B 1 395 ? -21.146 52.162  29.549  1    122.87 ? 384 ASP B N   1 -0.194 0.478  0.074  
ATOM   6062  C  CA  . ASP B 1 395 ? -22.171 51.701  30.468  1    125.43 ? 384 ASP B CA  1 -0.203 0.474  0.076  
ATOM   6063  C  C   . ASP B 1 395 ? -23.549 52.108  29.96   1    124.53 ? 384 ASP B C   1 -0.216 0.478  0.075  
ATOM   6064  O  O   . ASP B 1 395 ? -24.413 51.262  29.697  1    121.71 ? 384 ASP B O   1 -0.224 0.47   0.074  
ATOM   6065  C  CB  . ASP B 1 395 ? -21.879 52.295  31.857  1    126.83 ? 384 ASP B CB  1 -0.201 0.479  0.08   
ATOM   6066  C  CG  . ASP B 1 395 ? -22.61  51.594  32.978  1    133.59 ? 384 ASP B CG  1 -0.207 0.473  0.082  
ATOM   6067  O  OD1 . ASP B 1 395 ? -23.479 50.738  32.688  1    136.55 ? 384 ASP B OD1 1 -0.215 0.465  0.082  
ATOM   6068  O  OD2 . ASP B 1 395 ? -22.305 51.905  34.155  1    132.72 ? 384 ASP B OD2 1 -0.204 0.476  0.085  
ATOM   6069  N  N   . THR B 1 396 ? -23.754 53.416  29.789  1    122.86 ? 385 THR B N   1 -0.218 0.49   0.074  
ATOM   6070  C  CA  . THR B 1 396 ? -25.064 53.992  29.522  1    118.35 ? 385 THR B CA  1 -0.23  0.495  0.074  
ATOM   6071  C  C   . THR B 1 396 ? -24.915 55.174  28.576  1    109.64 ? 385 THR B C   1 -0.228 0.506  0.071  
ATOM   6072  O  O   . THR B 1 396 ? -23.835 55.753  28.429  1    106.15 ? 385 THR B O   1 -0.218 0.511  0.071  
ATOM   6073  C  CB  . THR B 1 396 ? -25.768 54.493  30.813  1    119.22 ? 385 THR B CB  1 -0.236 0.499  0.077  
ATOM   6074  O  OG1 . THR B 1 396 ? -25.337 55.832  31.117  1    116.8  ? 385 THR B OG1 1 -0.232 0.512  0.078  
ATOM   6075  C  CG2 . THR B 1 396 ? -25.462 53.61   32.013  1    120.11 ? 385 THR B CG2 1 -0.233 0.491  0.08   
ATOM   6076  N  N   . ILE B 1 397 ? -26.036 55.554  27.971  1    107.25 ? 386 ILE B N   1 -0.239 0.509  0.07   
ATOM   6077  C  CA  . ILE B 1 397 ? -26.15  56.798  27.217  1    106.86 ? 386 ILE B CA  1 -0.24  0.521  0.068  
ATOM   6078  C  C   . ILE B 1 397 ? -27.425 57.505  27.655  1    104.09 ? 386 ILE B C   1 -0.251 0.527  0.069  
ATOM   6079  O  O   . ILE B 1 397 ? -28.498 56.889  27.708  1    102.48 ? 386 ILE B O   1 -0.261 0.521  0.069  
ATOM   6080  C  CB  . ILE B 1 397 ? -26.166 56.557  25.693  1    107.95 ? 386 ILE B CB  1 -0.24  0.518  0.064  
ATOM   6081  C  CG1 . ILE B 1 397 ? -24.843 55.945  25.237  1    110.75 ? 386 ILE B CG1 1 -0.228 0.513  0.063  
ATOM   6082  C  CG2 . ILE B 1 397 ? -26.395 57.857  24.932  1    103.09 ? 386 ILE B CG2 1 -0.242 0.53   0.062  
ATOM   6083  C  CD1 . ILE B 1 397 ? -24.946 55.224  23.925  1    119.54 ? 386 ILE B CD1 1 -0.229 0.506  0.06   
ATOM   6084  N  N   . TYR B 1 398 ? -27.311 58.792  27.959  1    98.52  ? 387 TYR B N   1 -0.25  0.539  0.07   
ATOM   6085  C  CA  . TYR B 1 398 ? -28.469 59.606  28.281  1    98.91  ? 387 TYR B CA  1 -0.261 0.546  0.071  
ATOM   6086  C  C   . TYR B 1 398 ? -28.514 60.827  27.382  1    103.59 ? 387 TYR B C   1 -0.261 0.557  0.068  
ATOM   6087  O  O   . TYR B 1 398 ? -27.502 61.512  27.193  1    103.24 ? 387 TYR B O   1 -0.252 0.564  0.068  
ATOM   6088  C  CB  . TYR B 1 398 ? -28.461 60.068  29.723  1    101.59 ? 387 TYR B CB  1 -0.261 0.55   0.074  
ATOM   6089  C  CG  . TYR B 1 398 ? -29.602 61.011  30.029  1    101.54 ? 387 TYR B CG  1 -0.271 0.559  0.075  
ATOM   6090  C  CD1 . TYR B 1 398 ? -30.899 60.532  30.196  1    101.26 ? 387 TYR B CD1 1 -0.283 0.555  0.075  
ATOM   6091  C  CD2 . TYR B 1 398 ? -29.388 62.378  30.142  1    104.17 ? 387 TYR B CD2 1 -0.269 0.572  0.075  
ATOM   6092  C  CE1 . TYR B 1 398 ? -31.951 61.385  30.479  1    101.39 ? 387 TYR B CE1 1 -0.293 0.563  0.076  
ATOM   6093  C  CE2 . TYR B 1 398 ? -30.433 63.243  30.423  1    105.92 ? 387 TYR B CE2 1 -0.279 0.58   0.076  
ATOM   6094  C  CZ  . TYR B 1 398 ? -31.71  62.742  30.596  1    105.83 ? 387 TYR B CZ  1 -0.291 0.575  0.076  
ATOM   6095  O  OH  . TYR B 1 398 ? -32.741 63.607  30.891  1    104.74 ? 387 TYR B OH  1 -0.3   0.583  0.077  
ATOM   6096  N  N   . TRP B 1 399 ? -29.712 61.105  26.867  1    104.63 ? 388 TRP B N   1 -0.272 0.56   0.067  
ATOM   6097  C  CA  . TRP B 1 399 ? -29.973 62.165  25.905  1    103.38 ? 388 TRP B CA  1 -0.275 0.57   0.065  
ATOM   6098  C  C   . TRP B 1 399 ? -31.136 62.989  26.441  1    102.73 ? 388 TRP B C   1 -0.285 0.577  0.066  
ATOM   6099  O  O   . TRP B 1 399 ? -32.171 62.433  26.834  1    99.97  ? 388 TRP B O   1 -0.295 0.572  0.067  
ATOM   6100  C  CB  . TRP B 1 399 ? -30.29  61.566  24.528  1    100.48 ? 388 TRP B CB  1 -0.278 0.564  0.061  
ATOM   6101  C  CG  . TRP B 1 399 ? -30.539 62.529  23.386  1    105.43 ? 388 TRP B CG  1 -0.28  0.573  0.058  
ATOM   6102  C  CD1 . TRP B 1 399 ? -29.671 62.85   22.365  1    105.82 ? 388 TRP B CD1 1 -0.272 0.576  0.056  
ATOM   6103  C  CD2 . TRP B 1 399 ? -31.756 63.242  23.109  1    105.42 ? 388 TRP B CD2 1 -0.291 0.58   0.058  
ATOM   6104  N  NE1 . TRP B 1 399 ? -30.271 63.734  21.484  1    102.78 ? 388 TRP B NE1 1 -0.277 0.584  0.054  
ATOM   6105  C  CE2 . TRP B 1 399 ? -31.546 63.991  21.918  1    104.92 ? 388 TRP B CE2 1 -0.289 0.586  0.055  
ATOM   6106  C  CE3 . TRP B 1 399 ? -32.999 63.327  23.751  1    98.94  ? 388 TRP B CE3 1 -0.302 0.58   0.059  
ATOM   6107  C  CZ2 . TRP B 1 399 ? -32.532 64.812  21.37   1    100.41 ? 388 TRP B CZ2 1 -0.298 0.594  0.053  
ATOM   6108  C  CZ3 . TRP B 1 399 ? -33.977 64.149  23.204  1    98.6   ? 388 TRP B CZ3 1 -0.311 0.588  0.058  
ATOM   6109  C  CH2 . TRP B 1 399 ? -33.738 64.879  22.028  1    100.59 ? 388 TRP B CH2 1 -0.309 0.595  0.055  
ATOM   6110  N  N   . GLY B 1 400 ? -30.955 64.307  26.488  1    96.75  ? 389 GLY B N   1 -0.284 0.589  0.066  
ATOM   6111  C  CA  . GLY B 1 400 ? -31.964 65.152  27.077  1    95.16  ? 389 GLY B CA  1 -0.293 0.597  0.068  
ATOM   6112  C  C   . GLY B 1 400 ? -32.272 66.388  26.27   1    91.18  ? 389 GLY B C   1 -0.296 0.608  0.066  
ATOM   6113  O  O   . GLY B 1 400 ? -31.37  67.07   25.769  1    95.84  ? 389 GLY B O   1 -0.287 0.615  0.064  
ATOM   6114  N  N   . LEU B 1 401 ? -33.553 66.712  26.193  1    88.69  ? 390 LEU B N   1 -0.307 0.611  0.065  
ATOM   6115  C  CA  . LEU B 1 401 ? -34.076 67.778  25.343  1    95.42  ? 390 LEU B CA  1 -0.312 0.621  0.063  
ATOM   6116  C  C   . LEU B 1 401 ? -33.796 69.153  25.938  1    94.3   ? 390 LEU B C   1 -0.31  0.634  0.065  
ATOM   6117  O  O   . LEU B 1 401 ? -34.566 69.647  26.764  1    97.75  ? 390 LEU B O   1 -0.317 0.638  0.067  
ATOM   6118  C  CB  . LEU B 1 401 ? -35.572 67.571  25.183  1    101.4  ? 390 LEU B CB  1 -0.326 0.619  0.063  
ATOM   6119  C  CG  . LEU B 1 401 ? -36.466 68.175  24.1    1    104.84 ? 390 LEU B CG  1 -0.334 0.625  0.06   
ATOM   6120  C  CD1 . LEU B 1 401 ? -37.874 67.764  24.51   1    101.04 ? 390 LEU B CD1 1 -0.347 0.621  0.061  
ATOM   6121  C  CD2 . LEU B 1 401 ? -36.343 69.686  23.958  1    103.06 ? 390 LEU B CD2 1 -0.333 0.639  0.06   
ATOM   6122  N  N   . GLU B 1 402 ? -32.751 69.824  25.455  1    94.43  ? 391 GLU B N   1 -0.3   0.64   0.064  
ATOM   6123  C  CA  . GLU B 1 402 ? -32.547 71.222  25.822  1    94.39  ? 391 GLU B CA  1 -0.298 0.653  0.064  
ATOM   6124  C  C   . GLU B 1 402 ? -33.385 72.185  24.962  1    100.01 ? 391 GLU B C   1 -0.306 0.662  0.062  
ATOM   6125  O  O   . GLU B 1 402 ? -34.613 72.23   25.11   1    101.77 ? 391 GLU B O   1 -0.317 0.662  0.063  
ATOM   6126  C  CB  . GLU B 1 402 ? -31.055 71.546  25.762  1    93.22  ? 391 GLU B CB  1 -0.285 0.656  0.064  
ATOM   6127  C  CG  . GLU B 1 402 ? -30.203 70.624  26.649  1    97.33  ? 391 GLU B CG  1 -0.277 0.647  0.067  
ATOM   6128  C  CD  . GLU B 1 402 ? -30.591 70.658  28.17   1    107.77 ? 391 GLU B CD  1 -0.28  0.648  0.07   
ATOM   6129  O  OE1 . GLU B 1 402 ? -30.327 69.648  28.896  1    101.17 ? 391 GLU B OE1 1 -0.278 0.638  0.072  
ATOM   6130  O  OE2 . GLU B 1 402 ? -31.147 71.685  28.649  1    102.17 ? 391 GLU B OE2 1 -0.285 0.657  0.072  
ATOM   6131  N  N   . GLY B 1 403 ? -32.749 72.979  24.089  1    98.55  ? 392 GLY B N   1 -0.3   0.669  0.06   
ATOM   6132  C  CA  . GLY B 1 403 ? -33.457 73.913  23.228  1    102.74 ? 392 GLY B CA  1 -0.307 0.677  0.058  
ATOM   6133  C  C   . GLY B 1 403 ? -33.892 73.3    21.894  1    109.11 ? 392 GLY B C   1 -0.311 0.672  0.055  
ATOM   6134  O  O   . GLY B 1 403 ? -33.791 72.093  21.659  1    104.43 ? 392 GLY B O   1 -0.31  0.661  0.054  
ATOM   6135  N  N   . GLY B 1 404 ? -34.396 74.173  21.003  1    108.69 ? 393 GLY B N   1 -0.315 0.68   0.052  
ATOM   6136  C  CA  . GLY B 1 404 ? -34.845 73.79   19.663  1    106.48 ? 393 GLY B CA  1 -0.319 0.676  0.049  
ATOM   6137  C  C   . GLY B 1 404 ? -36.322 74.052  19.4    1    103.81 ? 393 GLY B C   1 -0.333 0.679  0.048  
ATOM   6138  O  O   . GLY B 1 404 ? -37.168 73.212  19.723  1    96.85  ? 393 GLY B O   1 -0.341 0.671  0.049  
ATOM   6139  N  N   . TYR B 1 405 ? -36.653 75.187  18.772  1    104.83 ? 394 TYR B N   1 -0.336 0.689  0.047  
ATOM   6140  C  CA  . TYR B 1 405 ? -37.967 75.78   18.971  1    107.93 ? 394 TYR B CA  1 -0.348 0.694  0.047  
ATOM   6141  C  C   . TYR B 1 405 ? -38.835 75.936  17.716  1    106.26 ? 394 TYR B C   1 -0.356 0.696  0.044  
ATOM   6142  O  O   . TYR B 1 405 ? -40.062 75.977  17.855  1    106.06 ? 394 TYR B O   1 -0.367 0.696  0.045  
ATOM   6143  C  CB  . TYR B 1 405 ? -37.807 77.14   19.682  1    106.7  ? 394 TYR B CB  1 -0.346 0.707  0.049  
ATOM   6144  C  CG  . TYR B 1 405 ? -36.986 77.042  20.984  1    114.27 ? 394 TYR B CG  1 -0.339 0.706  0.052  
ATOM   6145  C  CD1 . TYR B 1 405 ? -37.571 76.596  22.172  1    110.61 ? 394 TYR B CD1 1 -0.344 0.702  0.055  
ATOM   6146  C  CD2 . TYR B 1 405 ? -35.625 77.384  21.019  1    114.13 ? 394 TYR B CD2 1 -0.326 0.709  0.052  
ATOM   6147  C  CE1 . TYR B 1 405 ? -36.836 76.499  23.348  1    109.68 ? 394 TYR B CE1 1 -0.338 0.701  0.058  
ATOM   6148  C  CE2 . TYR B 1 405 ? -34.876 77.29   22.205  1    110.23 ? 394 TYR B CE2 1 -0.32  0.708  0.055  
ATOM   6149  C  CZ  . TYR B 1 405 ? -35.491 76.84   23.361  1    112.78 ? 394 TYR B CZ  1 -0.325 0.704  0.058  
ATOM   6150  O  OH  . TYR B 1 405 ? -34.775 76.726  24.543  1    114.07 ? 394 TYR B OH  1 -0.319 0.703  0.061  
ATOM   6151  N  N   . ASP B 1 406 ? -38.268 75.995  16.51   1    106.47 ? 395 ASP B N   1 -0.351 0.696  0.041  
ATOM   6152  C  CA  . ASP B 1 406 ? -39.083 76.203  15.306  1    110.53 ? 395 ASP B CA  1 -0.358 0.698  0.038  
ATOM   6153  C  C   . ASP B 1 406 ? -39.774 74.903  14.876  1    105.74 ? 395 ASP B C   1 -0.364 0.686  0.037  
ATOM   6154  O  O   . ASP B 1 406 ? -39.097 73.919  14.548  1    103.98 ? 395 ASP B O   1 -0.358 0.677  0.036  
ATOM   6155  C  CB  . ASP B 1 406 ? -38.225 76.747  14.166  1    109.34 ? 395 ASP B CB  1 -0.35  0.703  0.035  
ATOM   6156  C  CG  . ASP B 1 406 ? -38.969 76.764  12.849  1    111.78 ? 395 ASP B CG  1 -0.357 0.703  0.032  
ATOM   6157  O  OD1 . ASP B 1 406 ? -39.791 77.691  12.662  1    114.62 ? 395 ASP B OD1 1 -0.365 0.712  0.032  
ATOM   6158  O  OD2 . ASP B 1 406 ? -38.746 75.847  12.017  1    109.33 ? 395 ASP B OD2 1 -0.355 0.695  0.03   
ATOM   6159  N  N   . ARG B 1 407 ? -41.117 74.918  14.819  1    100.88 ? 396 ARG B N   1 -0.377 0.687  0.037  
ATOM   6160  C  CA  . ARG B 1 407 ? -41.884 73.668  14.798  1    99.76  ? 396 ARG B CA  1 -0.384 0.675  0.037  
ATOM   6161  C  C   . ARG B 1 407 ? -41.504 72.771  13.63   1    104.59 ? 396 ARG B C   1 -0.38  0.667  0.034  
ATOM   6162  O  O   . ARG B 1 407 ? -41.139 71.605  13.827  1    102.58 ? 396 ARG B O   1 -0.377 0.656  0.035  
ATOM   6163  C  CB  . ARG B 1 407 ? -43.384 73.923  14.761  1    99.81  ? 396 ARG B CB  1 -0.398 0.677  0.037  
ATOM   6164  C  CG  . ARG B 1 407 ? -44.145 72.612  14.61   1    93.91  ? 396 ARG B CG  1 -0.405 0.665  0.036  
ATOM   6165  C  CD  . ARG B 1 407 ? -45.594 72.738  15.022  1    102.68 ? 396 ARG B CD  1 -0.418 0.667  0.038  
ATOM   6166  N  NE  . ARG B 1 407 ? -46.263 71.443  15.028  1    104.83 ? 396 ARG B NE  1 -0.424 0.655  0.038  
ATOM   6167  C  CZ  . ARG B 1 407 ? -47.576 71.283  15.136  1    108.34 ? 396 ARG B CZ  1 -0.436 0.653  0.038  
ATOM   6168  N  NH1 . ARG B 1 407 ? -48.388 72.32   15.274  1    105.3  ? 396 ARG B NH1 1 -0.443 0.663  0.038  
ATOM   6169  N  NH2 . ARG B 1 407 ? -48.089 70.054  15.093  1    107.43 ? 396 ARG B NH2 1 -0.441 0.642  0.038  
ATOM   6170  N  N   . THR B 1 408 ? -41.625 73.274  12.398  1    108.3  ? 397 THR B N   1 -0.381 0.671  0.031  
ATOM   6171  C  CA  . THR B 1 408 ? -41.379 72.399  11.257  1    104.05 ? 397 THR B CA  1 -0.379 0.663  0.028  
ATOM   6172  C  C   . THR B 1 408 ? -39.964 71.838  11.308  1    102.99 ? 397 THR B C   1 -0.366 0.658  0.028  
ATOM   6173  O  O   . THR B 1 408 ? -39.746 70.665  10.985  1    106.18 ? 397 THR B O   1 -0.364 0.648  0.027  
ATOM   6174  C  CB  . THR B 1 408 ? -41.626 73.137  9.944   1    106.34 ? 397 THR B CB  1 -0.381 0.67   0.025  
ATOM   6175  O  OG1 . THR B 1 408 ? -40.612 74.131  9.758   1    110.98 ? 397 THR B OG1 1 -0.372 0.679  0.024  
ATOM   6176  C  CG2 . THR B 1 408 ? -43.009 73.794  9.955   1    105.47 ? 397 THR B CG2 1 -0.394 0.676  0.025  
ATOM   6177  N  N   . MET B 1 409 ? -39     72.642  11.766  1    99.29  ? 398 MET B N   1 -0.357 0.666  0.029  
ATOM   6178  C  CA  . MET B 1 409 ? -37.636 72.141  11.899  1    96.83  ? 398 MET B CA  1 -0.345 0.661  0.03   
ATOM   6179  C  C   . MET B 1 409 ? -37.548 71.057  12.975  1    101.89 ? 398 MET B C   1 -0.344 0.651  0.032  
ATOM   6180  O  O   . MET B 1 409 ? -36.969 69.986  12.745  1    97.44  ? 398 MET B O   1 -0.339 0.641  0.032  
ATOM   6181  C  CB  . MET B 1 409 ? -36.678 73.301  12.184  1    91.73  ? 398 MET B CB  1 -0.336 0.672  0.03   
ATOM   6182  C  CG  . MET B 1 409 ? -35.213 72.887  12.331  1    100.93 ? 398 MET B CG  1 -0.323 0.668  0.031  
ATOM   6183  S  SD  . MET B 1 409 ? -34.811 72.114  13.942  1    116.61 ? 398 MET B SD  1 -0.319 0.661  0.035  
ATOM   6184  C  CE  . MET B 1 409 ? -33.898 73.405  14.804  1    104.48 ? 398 MET B CE  1 -0.311 0.673  0.037  
ATOM   6185  N  N   . TYR B 1 410 ? -38.116 71.304  14.161  1    103.28 ? 399 TYR B N   1 -0.349 0.653  0.035  
ATOM   6186  C  CA  . TYR B 1 410 ? -37.913 70.338  15.235  1    102.04 ? 399 TYR B CA  1 -0.347 0.645  0.038  
ATOM   6187  C  C   . TYR B 1 410 ? -38.779 69.09   15.078  1    101.97 ? 399 TYR B C   1 -0.355 0.633  0.038  
ATOM   6188  O  O   . TYR B 1 410 ? -38.436 68.042  15.644  1    96.68  ? 399 TYR B O   1 -0.352 0.624  0.039  
ATOM   6189  C  CB  . TYR B 1 410 ? -38.115 70.991  16.618  1    96.63  ? 399 TYR B CB  1 -0.349 0.651  0.041  
ATOM   6190  C  CG  . TYR B 1 410 ? -39.524 71.362  17.084  1    97     ? 399 TYR B CG  1 -0.362 0.654  0.043  
ATOM   6191  C  CD1 . TYR B 1 410 ? -40.511 70.4    17.247  1    93.39  ? 399 TYR B CD1 1 -0.371 0.645  0.043  
ATOM   6192  C  CD2 . TYR B 1 410 ? -39.83  72.671  17.451  1    97.21  ? 399 TYR B CD2 1 -0.365 0.666  0.044  
ATOM   6193  C  CE1 . TYR B 1 410 ? -41.777 70.733  17.695  1    97.28  ? 399 TYR B CE1 1 -0.383 0.648  0.044  
ATOM   6194  C  CE2 . TYR B 1 410 ? -41.094 73.012  17.914  1    96.34  ? 399 TYR B CE2 1 -0.377 0.669  0.045  
ATOM   6195  C  CZ  . TYR B 1 410 ? -42.065 72.036  18.032  1    97.92  ? 399 TYR B CZ  1 -0.385 0.66   0.045  
ATOM   6196  O  OH  . TYR B 1 410 ? -43.326 72.359  18.495  1    98.02  ? 399 TYR B OH  1 -0.397 0.663  0.046  
ATOM   6197  N  N   . GLU B 1 411 ? -39.882 69.171  14.324  1    104.47 ? 400 GLU B N   1 -0.365 0.634  0.036  
ATOM   6198  C  CA  . GLU B 1 411 ? -40.612 67.955  13.985  1    102.16 ? 400 GLU B CA  1 -0.372 0.623  0.035  
ATOM   6199  C  C   . GLU B 1 411 ? -39.803 67.102  13.022  1    103.82 ? 400 GLU B C   1 -0.365 0.615  0.033  
ATOM   6200  O  O   . GLU B 1 411 ? -39.822 65.868  13.114  1    102.25 ? 400 GLU B O   1 -0.365 0.604  0.033  
ATOM   6201  C  CB  . GLU B 1 411 ? -41.98  68.294  13.389  1    96.29  ? 400 GLU B CB  1 -0.385 0.626  0.033  
ATOM   6202  C  CG  . GLU B 1 411 ? -42.845 69.148  14.282  1    104.8  ? 400 GLU B CG  1 -0.393 0.634  0.036  
ATOM   6203  C  CD  . GLU B 1 411 ? -44.311 68.751  14.268  1    113.3  ? 400 GLU B CD  1 -0.406 0.63   0.036  
ATOM   6204  O  OE1 . GLU B 1 411 ? -44.874 68.65   13.148  1    111.46 ? 400 GLU B OE1 1 -0.411 0.629  0.033  
ATOM   6205  O  OE2 . GLU B 1 411 ? -44.895 68.544  15.377  1    108.51 ? 400 GLU B OE2 1 -0.411 0.628  0.038  
ATOM   6206  N  N   . ARG B 1 412 ? -39.057 67.743  12.119  1    98.24  ? 401 ARG B N   1 -0.358 0.621  0.03   
ATOM   6207  C  CA  . ARG B 1 412 ? -38.26  66.988  11.161  1    103.73 ? 401 ARG B CA  1 -0.351 0.614  0.028  
ATOM   6208  C  C   . ARG B 1 412 ? -37.021 66.376  11.817  1    102.83 ? 401 ARG B C   1 -0.339 0.608  0.03   
ATOM   6209  O  O   . ARG B 1 412 ? -36.725 65.197  11.606  1    107.5  ? 401 ARG B O   1 -0.337 0.597  0.029  
ATOM   6210  C  CB  . ARG B 1 412 ? -37.872 67.877  9.973   1    100    ? 401 ARG B CB  1 -0.347 0.622  0.025  
ATOM   6211  C  CG  . ARG B 1 412 ? -36.995 67.172  8.953   1    105.06 ? 401 ARG B CG  1 -0.339 0.616  0.022  
ATOM   6212  C  CD  . ARG B 1 412 ? -36.827 67.971  7.665   1    111.34 ? 401 ARG B CD  1 -0.337 0.623  0.019  
ATOM   6213  N  NE  . ARG B 1 412 ? -35.613 68.776  7.676   1    105.57 ? 401 ARG B NE  1 -0.326 0.63   0.019  
ATOM   6214  C  CZ  . ARG B 1 412 ? -35.593 70.093  7.823   1    107.12 ? 401 ARG B CZ  1 -0.326 0.642  0.02   
ATOM   6215  N  NH1 . ARG B 1 412 ? -36.711 70.792  7.951   1    97.22  ? 401 ARG B NH1 1 -0.336 0.649  0.02   
ATOM   6216  N  NH2 . ARG B 1 412 ? -34.423 70.725  7.838   1    108.89 ? 401 ARG B NH2 1 -0.315 0.648  0.02   
ATOM   6217  N  N   . GLU B 1 413 ? -36.284 67.155  12.615  1    98.5   ? 402 GLU B N   1 -0.333 0.615  0.031  
ATOM   6218  C  CA  . GLU B 1 413 ? -35.078 66.614  13.239  1    102.81 ? 402 GLU B CA  1 -0.321 0.61   0.033  
ATOM   6219  C  C   . GLU B 1 413 ? -35.392 65.447  14.165  1    100.83 ? 402 GLU B C   1 -0.324 0.6    0.035  
ATOM   6220  O  O   . GLU B 1 413 ? -34.601 64.501  14.269  1    98.9   ? 402 GLU B O   1 -0.317 0.591  0.036  
ATOM   6221  C  CB  . GLU B 1 413 ? -34.341 67.704  14.013  1    104.53 ? 402 GLU B CB  1 -0.315 0.62   0.035  
ATOM   6222  C  CG  . GLU B 1 413 ? -33.994 68.905  13.166  1    110.93 ? 402 GLU B CG  1 -0.312 0.631  0.033  
ATOM   6223  C  CD  . GLU B 1 413 ? -32.91  68.624  12.115  1    116.08 ? 402 GLU B CD  1 -0.302 0.629  0.03   
ATOM   6224  O  OE1 . GLU B 1 413 ? -32.576 69.566  11.349  1    110.36 ? 402 GLU B OE1 1 -0.299 0.638  0.028  
ATOM   6225  O  OE2 . GLU B 1 413 ? -32.384 67.481  12.071  1    118.02 ? 402 GLU B OE2 1 -0.297 0.618  0.03   
ATOM   6226  N  N   . LEU B 1 414 ? -36.517 65.515  14.883  1    100.63 ? 403 LEU B N   1 -0.335 0.6    0.037  
ATOM   6227  C  CA  . LEU B 1 414 ? -36.904 64.397  15.734  1    99.64  ? 403 LEU B CA  1 -0.338 0.59   0.039  
ATOM   6228  C  C   . LEU B 1 414 ? -37.082 63.127  14.909  1    103.35 ? 403 LEU B C   1 -0.34  0.579  0.037  
ATOM   6229  O  O   . LEU B 1 414 ? -36.601 62.05   15.297  1    97.84  ? 403 LEU B O   1 -0.335 0.569  0.038  
ATOM   6230  C  CB  . LEU B 1 414 ? -38.186 64.729  16.503  1    97.59  ? 403 LEU B CB  1 -0.35  0.593  0.041  
ATOM   6231  C  CG  . LEU B 1 414 ? -38.566 63.695  17.575  1    103.1  ? 403 LEU B CG  1 -0.353 0.584  0.044  
ATOM   6232  C  CD1 . LEU B 1 414 ? -37.344 63.328  18.41   1    103.17 ? 403 LEU B CD1 1 -0.342 0.58   0.046  
ATOM   6233  C  CD2 . LEU B 1 414 ? -39.697 64.192  18.478  1    99.57  ? 403 LEU B CD2 1 -0.364 0.588  0.046  
ATOM   6234  N  N   . LYS B 1 415 ? -37.75  63.242  13.749  1    104.09 ? 404 LYS B N   1 -0.346 0.58   0.034  
ATOM   6235  C  CA  . LYS B 1 415 ? -37.987 62.068  12.913  1    97.15  ? 404 LYS B CA  1 -0.348 0.569  0.032  
ATOM   6236  C  C   . LYS B 1 415 ? -36.664 61.47   12.452  1    95.59  ? 404 LYS B C   1 -0.336 0.563  0.031  
ATOM   6237  O  O   . LYS B 1 415 ? -36.526 60.243  12.372  1    93.49  ? 404 LYS B O   1 -0.335 0.552  0.031  
ATOM   6238  C  CB  . LYS B 1 415 ? -38.886 62.445  11.735  1    102.65 ? 404 LYS B CB  1 -0.356 0.572  0.029  
ATOM   6239  C  CG  . LYS B 1 415 ? -39.636 61.293  11.058  1    112.46 ? 404 LYS B CG  1 -0.363 0.562  0.028  
ATOM   6240  C  CD  . LYS B 1 415 ? -40.211 61.726  9.672   1    109.4  ? 404 LYS B CD  1 -0.368 0.566  0.024  
ATOM   6241  C  CE  . LYS B 1 415 ? -40.678 60.516  8.835   1    119.97 ? 404 LYS B CE  1 -0.373 0.555  0.022  
ATOM   6242  N  NZ  . LYS B 1 415 ? -41.686 60.826  7.763   1    117.71 ? 404 LYS B NZ  1 -0.382 0.557  0.019  
ATOM   6243  N  N   . ILE B 1 416 ? -35.673 62.327  12.18   1    95.95  ? 405 ILE B N   1 -0.327 0.571  0.03   
ATOM   6244  C  CA  . ILE B 1 416 ? -34.298 61.875  11.96   1    93.58  ? 405 ILE B CA  1 -0.314 0.567  0.03   
ATOM   6245  C  C   . ILE B 1 416 ? -33.81  61.083  13.164  1    101.6  ? 405 ILE B C   1 -0.31  0.56   0.033  
ATOM   6246  O  O   . ILE B 1 416 ? -33.358 59.936  13.039  1    100.43 ? 405 ILE B O   1 -0.306 0.549  0.033  
ATOM   6247  C  CB  . ILE B 1 416 ? -33.372 63.075  11.688  1    95.64  ? 405 ILE B CB  1 -0.306 0.578  0.029  
ATOM   6248  C  CG1 . ILE B 1 416 ? -33.628 63.668  10.3    1    96.31  ? 405 ILE B CG1 1 -0.308 0.583  0.026  
ATOM   6249  C  CG2 . ILE B 1 416 ? -31.901 62.701  11.914  1    89.08  ? 405 ILE B CG2 1 -0.292 0.575  0.03   
ATOM   6250  C  CD1 . ILE B 1 416 ? -32.518 64.55   9.825   1    100.58 ? 405 ILE B CD1 1 -0.298 0.592  0.025  
ATOM   6251  N  N   . LEU B 1 417 ? -33.89  61.703  14.352  1    103.96 ? 406 LEU B N   1 -0.311 0.565  0.036  
ATOM   6252  C  CA  . LEU B 1 417 ? -33.401 61.075  15.573  1    98.19  ? 406 LEU B CA  1 -0.306 0.56   0.039  
ATOM   6253  C  C   . LEU B 1 417 ? -34.112 59.754  15.82   1    101.32 ? 406 LEU B C   1 -0.313 0.548  0.039  
ATOM   6254  O  O   . LEU B 1 417 ? -33.484 58.751  16.178  1    103.91 ? 406 LEU B O   1 -0.307 0.538  0.04   
ATOM   6255  C  CB  . LEU B 1 417 ? -33.584 62.026  16.764  1    101.05 ? 406 LEU B CB  1 -0.308 0.568  0.042  
ATOM   6256  C  CG  . LEU B 1 417 ? -32.744 61.805  18.034  1    101.07 ? 406 LEU B CG  1 -0.3   0.566  0.045  
ATOM   6257  C  CD1 . LEU B 1 417 ? -33.232 60.603  18.826  1    99.94  ? 406 LEU B CD1 1 -0.305 0.555  0.047  
ATOM   6258  C  CD2 . LEU B 1 417 ? -31.26  61.671  17.698  1    94.44  ? 406 LEU B CD2 1 -0.286 0.565  0.044  
ATOM   6259  N  N   . LEU B 1 418 ? -35.431 59.733  15.63   1    97.07  ? 407 LEU B N   1 -0.325 0.547  0.039  
ATOM   6260  C  CA  . LEU B 1 418 ? -36.174 58.511  15.897  1    101.27 ? 407 LEU B CA  1 -0.332 0.536  0.04   
ATOM   6261  C  C   . LEU B 1 418 ? -35.757 57.399  14.951  1    105.35 ? 407 LEU B C   1 -0.328 0.526  0.037  
ATOM   6262  O  O   . LEU B 1 418 ? -35.602 56.243  15.372  1    105.2  ? 407 LEU B O   1 -0.326 0.515  0.038  
ATOM   6263  C  CB  . LEU B 1 418 ? -37.668 58.777  15.781  1    103.04 ? 407 LEU B CB  1 -0.345 0.539  0.039  
ATOM   6264  C  CG  . LEU B 1 418 ? -38.194 59.58   16.952  1    102.4  ? 407 LEU B CG  1 -0.35  0.546  0.042  
ATOM   6265  C  CD1 . LEU B 1 418 ? -39.692 59.72   16.835  1    100.07 ? 407 LEU B CD1 1 -0.364 0.547  0.042  
ATOM   6266  C  CD2 . LEU B 1 418 ? -37.784 58.844  18.215  1    101.48 ? 407 LEU B CD2 1 -0.346 0.539  0.045  
ATOM   6267  N  N   . GLN B 1 419 ? -35.572 57.734  13.668  1    102.41 ? 408 GLN B N   1 -0.326 0.529  0.034  
ATOM   6268  C  CA  . GLN B 1 419 ? -35.177 56.743  12.675  1    97.5   ? 408 GLN B CA  1 -0.322 0.52   0.032  
ATOM   6269  C  C   . GLN B 1 419 ? -33.841 56.105  13.044  1    97.56  ? 408 GLN B C   1 -0.31  0.514  0.033  
ATOM   6270  O  O   . GLN B 1 419 ? -33.734 54.875  13.141  1    96.96  ? 408 GLN B O   1 -0.309 0.503  0.033  
ATOM   6271  C  CB  . GLN B 1 419 ? -35.118 57.392  11.287  1    104.92 ? 408 GLN B CB  1 -0.322 0.526  0.028  
ATOM   6272  C  CG  . GLN B 1 419 ? -36.485 57.566  10.61   1    103.37 ? 408 GLN B CG  1 -0.334 0.528  0.026  
ATOM   6273  C  CD  . GLN B 1 419 ? -36.49  58.599  9.484   1    94.27  ? 408 GLN B CD  1 -0.334 0.537  0.024  
ATOM   6274  O  OE1 . GLN B 1 419 ? -35.466 59.22   9.177   1    88.33  ? 408 GLN B OE1 1 -0.325 0.543  0.023  
ATOM   6275  N  NE2 . GLN B 1 419 ? -37.66  58.799  8.879   1    90.82  ? 408 GLN B NE2 1 -0.345 0.539  0.022  
ATOM   6276  N  N   . VAL B 1 420 ? -32.814 56.93   13.285  1    97.81  ? 409 VAL B N   1 -0.301 0.522  0.033  
ATOM   6277  C  CA  . VAL B 1 420 ? -31.517 56.402  13.717  1    102.13 ? 409 VAL B CA  1 -0.289 0.517  0.034  
ATOM   6278  C  C   . VAL B 1 420 ? -31.658 55.539  14.975  1    107.49 ? 409 VAL B C   1 -0.29  0.509  0.037  
ATOM   6279  O  O   . VAL B 1 420 ? -30.951 54.53   15.123  1    105.58 ? 409 VAL B O   1 -0.284 0.5    0.038  
ATOM   6280  C  CB  . VAL B 1 420 ? -30.512 57.557  13.913  1    99.43  ? 409 VAL B CB  1 -0.28  0.527  0.035  
ATOM   6281  C  CG1 . VAL B 1 420 ? -29.344 57.114  14.766  1    106.78 ? 409 VAL B CG1 1 -0.269 0.523  0.037  
ATOM   6282  C  CG2 . VAL B 1 420 ? -29.993 58.031  12.571  1    104.11 ? 409 VAL B CG2 1 -0.275 0.532  0.031  
ATOM   6283  N  N   . ILE B 1 421 ? -32.581 55.899  15.884  1    103.16 ? 410 ILE B N   1 -0.299 0.512  0.04   
ATOM   6284  C  CA  . ILE B 1 421 ? -32.852 55.068  17.059  1    106.09 ? 410 ILE B CA  1 -0.301 0.505  0.043  
ATOM   6285  C  C   . ILE B 1 421 ? -33.436 53.721  16.644  1    106.27 ? 410 ILE B C   1 -0.306 0.492  0.042  
ATOM   6286  O  O   . ILE B 1 421 ? -32.927 52.659  17.032  1    108.75 ? 410 ILE B O   1 -0.302 0.483  0.043  
ATOM   6287  C  CB  . ILE B 1 421 ? -33.782 55.806  18.042  1    110.7  ? 410 ILE B CB  1 -0.31  0.511  0.045  
ATOM   6288  C  CG1 . ILE B 1 421 ? -32.997 56.736  18.951  1    101.78 ? 410 ILE B CG1 1 -0.302 0.52   0.047  
ATOM   6289  C  CG2 . ILE B 1 421 ? -34.54  54.835  18.945  1    100.28 ? 410 ILE B CG2 1 -0.317 0.503  0.047  
ATOM   6290  C  CD1 . ILE B 1 421 ? -33.892 57.404  19.96   1    101.36 ? 410 ILE B CD1 1 -0.311 0.526  0.05   
ATOM   6291  N  N   . GLU B 1 422 ? -34.535 53.745  15.873  1    102.49 ? 411 GLU B N   1 -0.316 0.493  0.04   
ATOM   6292  C  CA  . GLU B 1 422 ? -35.158 52.504  15.416  1    106.54 ? 411 GLU B CA  1 -0.322 0.481  0.038  
ATOM   6293  C  C   . GLU B 1 422 ? -34.15  51.628  14.677  1    108.94 ? 411 GLU B C   1 -0.313 0.473  0.037  
ATOM   6294  O  O   . GLU B 1 422 ? -34.216 50.389  14.748  1    104.35 ? 411 GLU B O   1 -0.314 0.462  0.037  
ATOM   6295  C  CB  . GLU B 1 422 ? -36.367 52.835  14.53   1    103.49 ? 411 GLU B CB  1 -0.333 0.484  0.036  
ATOM   6296  C  CG  . GLU B 1 422 ? -37.27  51.652  14.174  1    112.25 ? 411 GLU B CG  1 -0.342 0.473  0.035  
ATOM   6297  C  CD  . GLU B 1 422 ? -38.113 51.909  12.914  1    122.04 ? 411 GLU B CD  1 -0.349 0.476  0.032  
ATOM   6298  O  OE1 . GLU B 1 422 ? -38.324 53.098  12.57   1    118.07 ? 411 GLU B OE1 1 -0.351 0.487  0.031  
ATOM   6299  O  OE2 . GLU B 1 422 ? -38.551 50.924  12.262  1    118.66 ? 411 GLU B OE2 1 -0.353 0.467  0.031  
ATOM   6300  N  N   . LYS B 1 423 ? -33.174 52.255  14.017  1    102.55 ? 412 LYS B N   1 -0.304 0.479  0.035  
ATOM   6301  C  CA  . LYS B 1 423 ? -32.199 51.493  13.253  1    104.71 ? 412 LYS B CA  1 -0.295 0.472  0.033  
ATOM   6302  C  C   . LYS B 1 423 ? -31.137 50.868  14.147  1    105.54 ? 412 LYS B C   1 -0.285 0.466  0.035  
ATOM   6303  O  O   . LYS B 1 423 ? -30.753 49.713  13.94   1    106.71 ? 412 LYS B O   1 -0.282 0.456  0.035  
ATOM   6304  C  CB  . LYS B 1 423 ? -31.549 52.395  12.219  1    103.93 ? 412 LYS B CB  1 -0.289 0.48   0.031  
ATOM   6305  C  CG  . LYS B 1 423 ? -30.716 51.648  11.234  1    106    ? 412 LYS B CG  1 -0.281 0.473  0.028  
ATOM   6306  C  CD  . LYS B 1 423 ? -30.001 52.639  10.349  1    112.32 ? 412 LYS B CD  1 -0.275 0.482  0.026  
ATOM   6307  C  CE  . LYS B 1 423 ? -29.011 53.496  11.103  1    108.65 ? 412 LYS B CE  1 -0.266 0.49   0.028  
ATOM   6308  N  NZ  . LYS B 1 423 ? -27.598 53.004  10.911  1    104.21 ? 412 LYS B NZ  1 -0.253 0.486  0.027  
ATOM   6309  N  N   . GLN B 1 424 ? -30.646 51.607  15.142  1    108.68 ? 413 GLN B N   1 -0.281 0.473  0.038  
ATOM   6310  C  CA  . GLN B 1 424 ? -29.458 51.19   15.88   1    116.46 ? 413 GLN B CA  1 -0.27  0.469  0.04   
ATOM   6311  C  C   . GLN B 1 424 ? -29.729 50.614  17.272  1    113.07 ? 413 GLN B C   1 -0.272 0.464  0.043  
ATOM   6312  O  O   . GLN B 1 424 ? -28.888 49.865  17.782  1    110.79 ? 413 GLN B O   1 -0.265 0.457  0.044  
ATOM   6313  C  CB  . GLN B 1 424 ? -28.492 52.374  16.016  1    114.98 ? 413 GLN B CB  1 -0.261 0.48   0.04   
ATOM   6314  C  CG  . GLN B 1 424 ? -27.026 51.98   16.004  1    115.27 ? 413 GLN B CG  1 -0.248 0.476  0.04   
ATOM   6315  C  CD  . GLN B 1 424 ? -26.477 52.038  14.612  1    114.75 ? 413 GLN B CD  1 -0.243 0.477  0.036  
ATOM   6316  O  OE1 . GLN B 1 424 ? -27.202 52.407  13.695  1    113.73 ? 413 GLN B OE1 1 -0.249 0.48   0.034  
ATOM   6317  N  NE2 . GLN B 1 424 ? -25.199 51.682  14.432  1    110.94 ? 413 GLN B NE2 1 -0.231 0.474  0.036  
ATOM   6318  N  N   . LEU B 1 425 ? -30.861 50.938  17.911  1    113.55 ? 414 LEU B N   1 -0.283 0.467  0.045  
ATOM   6319  C  CA  . LEU B 1 425 ? -31.076 50.543  19.302  1    121.18 ? 414 LEU B CA  1 -0.285 0.463  0.048  
ATOM   6320  C  C   . LEU B 1 425 ? -32.378 49.772  19.503  1    121.54 ? 414 LEU B C   1 -0.297 0.456  0.049  
ATOM   6321  O  O   . LEU B 1 425 ? -32.834 49.63   20.641  1    122.37 ? 414 LEU B O   1 -0.301 0.455  0.052  
ATOM   6322  C  CB  . LEU B 1 425 ? -31.044 51.77   20.22   1    115.97 ? 414 LEU B CB  1 -0.284 0.474  0.05   
ATOM   6323  C  CG  . LEU B 1 425 ? -29.889 52.739  19.95   1    111.49 ? 414 LEU B CG  1 -0.274 0.483  0.05   
ATOM   6324  C  CD1 . LEU B 1 425 ? -30.324 54.154  20.239  1    110.05 ? 414 LEU B CD1 1 -0.278 0.496  0.051  
ATOM   6325  C  CD2 . LEU B 1 425 ? -28.663 52.373  20.76   1    104.18 ? 414 LEU B CD2 1 -0.263 0.48   0.052  
ATOM   6326  N  N   . LEU B 1 426 ? -32.986 49.268  18.43   1    123.09 ? 415 LEU B N   1 -0.302 0.451  0.046  
ATOM   6327  C  CA  . LEU B 1 426 ? -34.222 48.498  18.52   1    130.87 ? 415 LEU B CA  1 -0.314 0.444  0.046  
ATOM   6328  C  C   . LEU B 1 426 ? -34.059 47.193  17.746  1    137.59 ? 415 LEU B C   1 -0.312 0.432  0.044  
ATOM   6329  O  O   . LEU B 1 426 ? -33.568 47.206  16.599  1    135.25 ? 415 LEU B O   1 -0.308 0.433  0.041  
ATOM   6330  C  CB  . LEU B 1 426 ? -35.421 49.297  17.982  1    127.32 ? 415 LEU B CB  1 -0.325 0.452  0.045  
ATOM   6331  C  CG  . LEU B 1 426 ? -36.148 50.252  18.93   1    119.43 ? 415 LEU B CG  1 -0.331 0.461  0.047  
ATOM   6332  C  CD1 . LEU B 1 426 ? -36.469 49.548  20.237  1    124.21 ? 415 LEU B CD1 1 -0.334 0.454  0.051  
ATOM   6333  C  CD2 . LEU B 1 426 ? -35.333 51.494  19.173  1    114.22 ? 415 LEU B CD2 1 -0.324 0.472  0.048  
ATOM   6334  N  N   . PRO B 1 427 ? -34.443 46.054  18.327  1    144.92 ? 416 PRO B N   1 -0.316 0.422  0.046  
ATOM   6335  C  CA  . PRO B 1 427 ? -34.189 44.765  17.667  1    149.8  ? 416 PRO B CA  1 -0.313 0.41   0.044  
ATOM   6336  C  C   . PRO B 1 427 ? -35.21  44.414  16.587  1    149.55 ? 416 PRO B C   1 -0.323 0.407  0.041  
ATOM   6337  O  O   . PRO B 1 427 ? -36.4   44.731  16.691  1    145.21 ? 416 PRO B O   1 -0.334 0.41   0.042  
ATOM   6338  C  CB  . PRO B 1 427 ? -34.244 43.76   18.832  1    149.1  ? 416 PRO B CB  1 -0.314 0.401  0.047  
ATOM   6339  C  CG  . PRO B 1 427 ? -34.055 44.6    20.093  1    142.42 ? 416 PRO B CG  1 -0.312 0.409  0.05   
ATOM   6340  C  CD  . PRO B 1 427 ? -34.753 45.886  19.759  1    137.8  ? 416 PRO B CD  1 -0.318 0.421  0.049  
ATOM   6341  N  N   . LYS B 1 428 ? -34.711 43.754  15.533  1    154.52 ? 417 LYS B N   1 -0.318 0.401  0.039  
ATOM   6342  C  CA  . LYS B 1 428 ? -35.507 43.144  14.465  1    159.35 ? 417 LYS B CA  1 -0.325 0.395  0.036  
ATOM   6343  C  C   . LYS B 1 428 ? -36.491 44.116  13.812  1    157.15 ? 417 LYS B C   1 -0.334 0.404  0.034  
ATOM   6344  O  O   . LYS B 1 428 ? -36.09  44.965  13.008  1    152.29 ? 417 LYS B O   1 -0.331 0.412  0.032  
ATOM   6345  C  CB  . LYS B 1 428 ? -36.26  41.92   15.003  1    160.19 ? 417 LYS B CB  1 -0.332 0.384  0.037  
ATOM   6346  C  CG  . LYS B 1 428 ? -36.673 40.916  13.928  1    158.01 ? 417 LYS B CG  1 -0.336 0.375  0.035  
ATOM   6347  C  CD  . LYS B 1 428 ? -37.748 39.962  14.436  1    158.49 ? 417 LYS B CD  1 -0.346 0.366  0.036  
ATOM   6348  C  CE  . LYS B 1 428 ? -37.336 39.291  15.74   1    164.13 ? 417 LYS B CE  1 -0.342 0.36   0.039  
ATOM   6349  N  NZ  . LYS B 1 428 ? -36.054 38.536  15.615  1    164.05 ? 417 LYS B NZ  1 -0.33  0.353  0.039  
ATOM   6350  N  N   . ASP B 1 429 ? -37.778 43.98   14.133  1    157.08 ? 418 ASP B N   1 -0.346 0.403  0.035  
ATOM   6351  C  CA  . ASP B 1 429 ? -38.821 44.857  13.599  1    152.6  ? 418 ASP B CA  1 -0.356 0.411  0.034  
ATOM   6352  C  C   . ASP B 1 429 ? -39.604 45.554  14.717  1    153.75 ? 418 ASP B C   1 -0.363 0.417  0.037  
ATOM   6353  O  O   . ASP B 1 429 ? -39.11  45.727  15.834  1    151.01 ? 418 ASP B O   1 -0.358 0.419  0.04   
ATOM   6354  C  CB  . ASP B 1 429 ? -39.787 44.065  12.713  1    154.17 ? 418 ASP B CB  1 -0.365 0.404  0.032  
ATOM   6355  C  CG  . ASP B 1 429 ? -40.829 44.953  12.038  1    157.8  ? 418 ASP B CG  1 -0.374 0.412  0.03   
ATOM   6356  O  OD1 . ASP B 1 429 ? -40.506 46.114  11.698  1    154.76 ? 418 ASP B OD1 1 -0.371 0.423  0.029  
ATOM   6357  O  OD2 . ASP B 1 429 ? -41.978 44.489  11.856  1    156.08 ? 418 ASP B OD2 1 -0.385 0.408  0.03   
ATOM   6358  N  N   . GLU C 1 38  ? -10.526 8.315   36.94   1    119.45 ? 27  GLU C N   1 -0.096 0.076  0.092  
ATOM   6359  C  CA  . GLU C 1 38  ? -11.361 9.149   37.814  1    125.24 ? 27  GLU C CA  1 -0.104 0.084  0.094  
ATOM   6360  C  C   . GLU C 1 38  ? -12.53  9.755   37.013  1    119.5  ? 27  GLU C C   1 -0.115 0.089  0.092  
ATOM   6361  O  O   . GLU C 1 38  ? -13.637 9.952   37.551  1    108.86 ? 27  GLU C O   1 -0.125 0.091  0.094  
ATOM   6362  C  CB  . GLU C 1 38  ? -10.499 10.242  38.484  1    123.21 ? 27  GLU C CB  1 -0.096 0.094  0.096  
ATOM   6363  C  CG  . GLU C 1 38  ? -11.256 11.434  39.079  1    120.2  ? 27  GLU C CG  1 -0.103 0.105  0.098  
ATOM   6364  C  CD  . GLU C 1 38  ? -11.809 11.16   40.465  1    128.92 ? 27  GLU C CD  1 -0.108 0.102  0.101  
ATOM   6365  O  OE1 . GLU C 1 38  ? -11.106 10.506  41.268  1    135.06 ? 27  GLU C OE1 1 -0.102 0.096  0.103  
ATOM   6366  O  OE2 . GLU C 1 38  ? -12.948 11.6    40.751  1    123.84 ? 27  GLU C OE2 1 -0.119 0.106  0.102  
ATOM   6367  N  N   . GLU C 1 39  ? -12.264 10.014  35.719  1    123.32 ? 28  GLU C N   1 -0.112 0.092  0.089  
ATOM   6368  C  CA  . GLU C 1 39  ? -13.267 10.566  34.799  1    116.38 ? 28  GLU C CA  1 -0.122 0.097  0.087  
ATOM   6369  C  C   . GLU C 1 39  ? -14.311 9.528   34.405  1    107.14 ? 28  GLU C C   1 -0.131 0.087  0.086  
ATOM   6370  O  O   . GLU C 1 39  ? -15.487 9.857   34.206  1    101.99 ? 28  GLU C O   1 -0.142 0.09   0.085  
ATOM   6371  C  CB  . GLU C 1 39  ? -12.585 11.092  33.54   1    112.74 ? 28  GLU C CB  1 -0.115 0.102  0.084  
ATOM   6372  C  CG  . GLU C 1 39  ? -11.862 12.403  33.704  1    126.92 ? 28  GLU C CG  1 -0.109 0.114  0.084  
ATOM   6373  C  CD  . GLU C 1 39  ? -12.796 13.529  34.118  1    135.7  ? 28  GLU C CD  1 -0.117 0.124  0.085  
ATOM   6374  O  OE1 . GLU C 1 39  ? -12.81  13.876  35.324  1    133.03 ? 28  GLU C OE1 1 -0.117 0.127  0.088  
ATOM   6375  O  OE2 . GLU C 1 39  ? -13.517 14.062  33.244  1    139.2  ? 28  GLU C OE2 1 -0.124 0.129  0.083  
ATOM   6376  N  N   . CYS C 1 40  ? -13.891 8.276   34.285  1    104.85 ? 29  CYS C N   1 -0.127 0.076  0.086  
ATOM   6377  C  CA  . CYS C 1 40  ? -14.719 7.191   33.787  1    107.41 ? 29  CYS C CA  1 -0.135 0.066  0.084  
ATOM   6378  C  C   . CYS C 1 40  ? -13.919 5.909   33.936  1    113.44 ? 29  CYS C C   1 -0.128 0.054  0.085  
ATOM   6379  O  O   . CYS C 1 40  ? -12.707 5.908   33.695  1    120.36 ? 29  CYS C O   1 -0.116 0.054  0.084  
ATOM   6380  C  CB  . CYS C 1 40  ? -15.092 7.427   32.313  1    118.57 ? 29  CYS C CB  1 -0.138 0.068  0.081  
ATOM   6381  S  SG  . CYS C 1 40  ? -15.704 5.997   31.394  1    111.47 ? 29  CYS C SG  1 -0.144 0.055  0.078  
ATOM   6382  N  N   . ALA C 1 41  ? -14.586 4.828   34.327  1    103.87 ? 30  ALA C N   1 -0.134 0.044  0.086  
ATOM   6383  C  CA  . ALA C 1 41  ? -13.913 3.541   34.305  1    105.6  ? 30  ALA C CA  1 -0.128 0.032  0.086  
ATOM   6384  C  C   . ALA C 1 41  ? -14.925 2.452   33.982  1    102.32 ? 30  ALA C C   1 -0.137 0.022  0.085  
ATOM   6385  O  O   . ALA C 1 41  ? -16.065 2.487   34.453  1    102.14 ? 30  ALA C O   1 -0.147 0.023  0.086  
ATOM   6386  C  CB  . ALA C 1 41  ? -13.189 3.26    35.627  1    100.93 ? 30  ALA C CB  1 -0.121 0.03   0.089  
ATOM   6387  N  N   . ILE C 1 42  ? -14.523 1.52    33.129  1    104.87 ? 31  ILE C N   1 -0.133 0.014  0.083  
ATOM   6388  C  CA  . ILE C 1 42  ? -15.311 0.319   32.891  1    107.33 ? 31  ILE C CA  1 -0.14  0.003  0.082  
ATOM   6389  C  C   . ILE C 1 42  ? -14.836 -0.728  33.891  1    100.84 ? 31  ILE C C   1 -0.136 -0.007 0.085  
ATOM   6390  O  O   . ILE C 1 42  ? -13.645 -1.056  33.957  1    100.11 ? 31  ILE C O   1 -0.125 -0.01  0.085  
ATOM   6391  C  CB  . ILE C 1 42  ? -15.191 -0.178  31.435  1    98.97  ? 31  ILE C CB  1 -0.139 -0.002 0.078  
ATOM   6392  C  CG1 . ILE C 1 42  ? -16.101 0.626   30.495  1    94.18  ? 31  ILE C CG1 1 -0.148 0.006  0.076  
ATOM   6393  C  CG2 . ILE C 1 42  ? -15.619 -1.624  31.325  1    91.89  ? 31  ILE C CG2 1 -0.143 -0.015 0.078  
ATOM   6394  C  CD1 . ILE C 1 42  ? -15.502 1.92    29.997  1    94.43  ? 31  ILE C CD1 1 -0.142 0.018  0.075  
ATOM   6395  N  N   . GLN C 1 43  ? -15.754 -1.239  34.689  1    92.09  ? 32  GLN C N   1 -0.144 -0.011 0.087  
ATOM   6396  C  CA  . GLN C 1 43  ? -15.412 -2.263  35.661  1    103.14 ? 32  GLN C CA  1 -0.141 -0.021 0.089  
ATOM   6397  C  C   . GLN C 1 43  ? -15.783 -3.633  35.117  1    99.74  ? 32  GLN C C   1 -0.145 -0.033 0.088  
ATOM   6398  O  O   . GLN C 1 43  ? -16.925 -3.857  34.696  1    101.36 ? 32  GLN C O   1 -0.155 -0.035 0.087  
ATOM   6399  C  CB  . GLN C 1 43  ? -16.12  -2.013  36.991  1    107.85 ? 32  GLN C CB  1 -0.148 -0.018 0.092  
ATOM   6400  C  CG  . GLN C 1 43  ? -15.76  -2.991  38.073  1    103.34 ? 32  GLN C CG  1 -0.144 -0.027 0.095  
ATOM   6401  C  CD  . GLN C 1 43  ? -16.51  -2.698  39.341  1    111.22 ? 32  GLN C CD  1 -0.151 -0.025 0.098  
ATOM   6402  O  OE1 . GLN C 1 43  ? -16.627 -1.536  39.747  1    113.44 ? 32  GLN C OE1 1 -0.152 -0.014 0.099  
ATOM   6403  N  NE2 . GLN C 1 43  ? -17.043 -3.743  39.975  1    111.95 ? 32  GLN C NE2 1 -0.156 -0.034 0.1    
ATOM   6404  N  N   . ILE C 1 44  ? -14.828 -4.55   35.139  1    98.47  ? 33  ILE C N   1 -0.136 -0.042 0.088  
ATOM   6405  C  CA  . ILE C 1 44  ? -15.123 -5.92   34.739  1    101.19 ? 33  ILE C CA  1 -0.139 -0.054 0.087  
ATOM   6406  C  C   . ILE C 1 44  ? -14.65  -6.835  35.862  1    97.11  ? 33  ILE C C   1 -0.134 -0.063 0.09   
ATOM   6407  O  O   . ILE C 1 44  ? -13.716 -6.478  36.594  1    96.72  ? 33  ILE C O   1 -0.126 -0.059 0.091  
ATOM   6408  C  CB  . ILE C 1 44  ? -14.47  -6.263  33.386  1    94.46  ? 33  ILE C CB  1 -0.133 -0.057 0.083  
ATOM   6409  C  CG1 . ILE C 1 44  ? -12.965 -6.053  33.434  1    92.86  ? 33  ILE C CG1 1 -0.119 -0.055 0.083  
ATOM   6410  C  CG2 . ILE C 1 44  ? -14.995 -5.363  32.328  1    95.36  ? 33  ILE C CG2 1 -0.137 -0.049 0.081  
ATOM   6411  C  CD1 . ILE C 1 44  ? -12.267 -6.706  32.309  1    89.34  ? 33  ILE C CD1 1 -0.112 -0.061 0.081  
ATOM   6412  N  N   . PRO C 1 45  ? -15.273 -7.995  36.058  1    91.93  ? 34  PRO C N   1 -0.14  -0.073 0.09   
ATOM   6413  C  CA  . PRO C 1 45  ? -14.713 -8.976  36.991  1    96.82  ? 34  PRO C CA  1 -0.135 -0.082 0.092  
ATOM   6414  C  C   . PRO C 1 45  ? -13.367 -9.45   36.488  1    99.94  ? 34  PRO C C   1 -0.122 -0.087 0.091  
ATOM   6415  O  O   . PRO C 1 45  ? -13.116 -9.497  35.281  1    107.73 ? 34  PRO C O   1 -0.12  -0.087 0.088  
ATOM   6416  C  CB  . PRO C 1 45  ? -15.731 -10.122 36.977  1    96.35  ? 34  PRO C CB  1 -0.144 -0.093 0.092  
ATOM   6417  C  CG  . PRO C 1 45  ? -16.914 -9.595  36.227  1    100.71 ? 34  PRO C CG  1 -0.155 -0.088 0.09   
ATOM   6418  C  CD  . PRO C 1 45  ? -16.433 -8.52   35.33   1    94.52  ? 34  PRO C CD  1 -0.151 -0.078 0.088  
ATOM   6419  N  N   . SER C 1 46  ? -12.494 -9.805  37.417  1    101.38 ? 35  SER C N   1 -0.114 -0.09  0.093  
ATOM   6420  C  CA  . SER C 1 46  ? -11.239 -10.401 36.997  1    107.66 ? 35  SER C CA  1 -0.103 -0.095 0.092  
ATOM   6421  C  C   . SER C 1 46  ? -11.477 -11.827 36.506  1    107.84 ? 35  SER C C   1 -0.105 -0.108 0.091  
ATOM   6422  O  O   . SER C 1 46  ? -12.561 -12.401 36.683  1    103.11 ? 35  SER C O   1 -0.115 -0.114 0.092  
ATOM   6423  C  CB  . SER C 1 46  ? -10.239 -10.407 38.141  1    107.49 ? 35  SER C CB  1 -0.094 -0.095 0.095  
ATOM   6424  O  OG  . SER C 1 46  ? -10.773 -11.113 39.24   1    105.81 ? 35  SER C OG  1 -0.099 -0.102 0.098  
ATOM   6425  N  N   . GLU C 1 47  ? -10.441 -12.4   35.883  1    109.14 ? 36  GLU C N   1 -0.096 -0.114 0.09   
ATOM   6426  C  CA  . GLU C 1 47  ? -10.534 -13.773 35.394  1    112.63 ? 36  GLU C CA  1 -0.097 -0.126 0.088  
ATOM   6427  C  C   . GLU C 1 47  ? -10.89  -14.722 36.534  1    112.55 ? 36  GLU C C   1 -0.1   -0.135 0.091  
ATOM   6428  O  O   . GLU C 1 47  ? -11.913 -15.417 36.487  1    108.04 ? 36  GLU C O   1 -0.109 -0.141 0.091  
ATOM   6429  C  CB  . GLU C 1 47  ? -9.219  -14.189 34.718  1    119.55 ? 36  GLU C CB  1 -0.084 -0.13  0.087  
ATOM   6430  C  CG  . GLU C 1 47  ? -9.317  -15.46  33.849  1    126.1  ? 36  GLU C CG  1 -0.085 -0.142 0.085  
ATOM   6431  C  CD  . GLU C 1 47  ? -7.957  -15.964 33.322  1    137.74 ? 36  GLU C CD  1 -0.073 -0.146 0.083  
ATOM   6432  O  OE1 . GLU C 1 47  ? -6.916  -15.3   33.564  1    137.31 ? 36  GLU C OE1 1 -0.063 -0.14  0.084  
ATOM   6433  O  OE2 . GLU C 1 47  ? -7.935  -17.037 32.664  1    137.12 ? 36  GLU C OE2 1 -0.073 -0.156 0.082  
ATOM   6434  N  N   . ILE C 1 48  ? -10.074 -14.72  37.595  1    108.89 ? 37  ILE C N   1 -0.092 -0.135 0.094  
ATOM   6435  C  CA  . ILE C 1 48  ? -10.277 -15.643 38.711  1    106.09 ? 37  ILE C CA  1 -0.094 -0.143 0.097  
ATOM   6436  C  C   . ILE C 1 48  ? -11.626 -15.396 39.383  1    101.95 ? 37  ILE C C   1 -0.107 -0.141 0.098  
ATOM   6437  O  O   . ILE C 1 48  ? -12.327 -16.338 39.781  1    96.22  ? 37  ILE C O   1 -0.113 -0.15  0.099  
ATOM   6438  C  CB  . ILE C 1 48  ? -9.108  -15.518 39.708  1    109.02 ? 37  ILE C CB  1 -0.083 -0.142 0.099  
ATOM   6439  C  CG1 . ILE C 1 48  ? -9.396  -16.317 40.972  1    92.64  ? 37  ILE C CG1 1 -0.086 -0.15  0.102  
ATOM   6440  C  CG2 . ILE C 1 48  ? -8.805  -14.04  40.019  1    112.78 ? 37  ILE C CG2 1 -0.081 -0.129 0.1    
ATOM   6441  C  CD1 . ILE C 1 48  ? -9.372  -17.797 40.74   1    91.98  ? 37  ILE C CD1 1 -0.086 -0.163 0.102  
ATOM   6442  N  N   . ASP C 1 49  ? -12.015 -14.13  39.518  1    98.31  ? 38  ASP C N   1 -0.11  -0.129 0.099  
ATOM   6443  C  CA  . ASP C 1 49  ? -13.33  -13.814 40.061  1    98.35  ? 38  ASP C CA  1 -0.122 -0.127 0.1    
ATOM   6444  C  C   . ASP C 1 49  ? -14.428 -14.379 39.172  1    100.4  ? 38  ASP C C   1 -0.132 -0.132 0.098  
ATOM   6445  O  O   . ASP C 1 49  ? -15.293 -15.133 39.631  1    94.16  ? 38  ASP C O   1 -0.14  -0.139 0.099  
ATOM   6446  C  CB  . ASP C 1 49  ? -13.482 -12.299 40.202  1    102.75 ? 38  ASP C CB  1 -0.124 -0.113 0.1    
ATOM   6447  C  CG  . ASP C 1 49  ? -13.107 -11.78  41.583  1    102.08 ? 38  ASP C CG  1 -0.12  -0.108 0.104  
ATOM   6448  O  OD1 . ASP C 1 49  ? -12.016 -12.127 42.125  1    93.55  ? 38  ASP C OD1 1 -0.11  -0.111 0.105  
ATOM   6449  O  OD2 . ASP C 1 49  ? -13.927 -10.991 42.102  1    101.98 ? 38  ASP C OD2 1 -0.128 -0.101 0.105  
ATOM   6450  N  N   . ASN C 1 50  ? -14.392 -14.013 37.878  1    109.9  ? 39  ASN C N   1 -0.132 -0.128 0.095  
ATOM   6451  C  CA  . ASN C 1 50  ? -15.357 -14.508 36.905  1    106.14 ? 39  ASN C CA  1 -0.141 -0.133 0.092  
ATOM   6452  C  C   . ASN C 1 50  ? -15.399 -16.029 36.856  1    105.63 ? 39  ASN C C   1 -0.141 -0.147 0.092  
ATOM   6453  O  O   . ASN C 1 50  ? -16.471 -16.607 36.657  1    106.66 ? 39  ASN C O   1 -0.151 -0.152 0.092  
ATOM   6454  C  CB  . ASN C 1 50  ? -15.043 -13.944 35.513  1    107.91 ? 39  ASN C CB  1 -0.138 -0.128 0.089  
ATOM   6455  C  CG  . ASN C 1 50  ? -15.916 -14.559 34.423  1    107.28 ? 39  ASN C CG  1 -0.146 -0.133 0.086  
ATOM   6456  O  OD1 . ASN C 1 50  ? -15.422 -15.017 33.388  1    105.25 ? 39  ASN C OD1 1 -0.141 -0.138 0.083  
ATOM   6457  N  ND2 . ASN C 1 50  ? -17.221 -14.609 34.678  1    108.11 ? 39  ASN C ND2 1 -0.158 -0.134 0.087  
ATOM   6458  N  N   . GLU C 1 51  ? -14.262 -16.695 37.079  1    107.02 ? 40  GLU C N   1 -0.131 -0.153 0.093  
ATOM   6459  C  CA  . GLU C 1 51  ? -14.229 -18.155 37.027  1    109.73 ? 40  GLU C CA  1 -0.13  -0.166 0.092  
ATOM   6460  C  C   . GLU C 1 51  ? -14.999 -18.831 38.171  1    110.59 ? 40  GLU C C   1 -0.137 -0.173 0.095  
ATOM   6461  O  O   . GLU C 1 51  ? -15.34  -20.014 38.041  1    113.14 ? 40  GLU C O   1 -0.141 -0.183 0.095  
ATOM   6462  C  CB  . GLU C 1 51  ? -12.765 -18.637 36.947  1    112.28 ? 40  GLU C CB  1 -0.117 -0.171 0.092  
ATOM   6463  C  CG  . GLU C 1 51  ? -12.169 -18.284 35.564  1    116.21 ? 40  GLU C CG  1 -0.112 -0.168 0.089  
ATOM   6464  C  CD  . GLU C 1 51  ? -10.969 -19.108 35.118  1    124.34 ? 40  GLU C CD  1 -0.101 -0.175 0.088  
ATOM   6465  O  OE1 . GLU C 1 51  ? -10.765 -20.222 35.644  1    127.77 ? 40  GLU C OE1 1 -0.099 -0.185 0.089  
ATOM   6466  O  OE2 . GLU C 1 51  ? -10.242 -18.633 34.209  1    124.92 ? 40  GLU C OE2 1 -0.094 -0.171 0.085  
ATOM   6467  N  N   . GLN C 1 52  ? -15.351 -18.126 39.25   1    107.38 ? 41  GLN C N   1 -0.141 -0.166 0.098  
ATOM   6468  C  CA  . GLN C 1 52  ? -16.226 -18.728 40.246  1    106.24 ? 41  GLN C CA  1 -0.149 -0.172 0.1    
ATOM   6469  C  C   . GLN C 1 52  ? -17.705 -18.476 39.966  1    106.06 ? 41  GLN C C   1 -0.162 -0.169 0.1    
ATOM   6470  O  O   . GLN C 1 52  ? -18.528 -18.591 40.884  1    102.27 ? 41  GLN C O   1 -0.17  -0.17  0.102  
ATOM   6471  C  CB  . GLN C 1 52  ? -15.897 -18.231 41.658  1    103.95 ? 41  GLN C CB  1 -0.146 -0.167 0.104  
ATOM   6472  C  CG  . GLN C 1 52  ? -14.457 -17.897 41.916  1    104.24 ? 41  GLN C CG  1 -0.132 -0.164 0.105  
ATOM   6473  C  CD  . GLN C 1 52  ? -13.552 -19.067 41.646  1    109.24 ? 41  GLN C CD  1 -0.124 -0.175 0.104  
ATOM   6474  O  OE1 . GLN C 1 52  ? -13.861 -20.205 42.004  1    110.31 ? 41  GLN C OE1 1 -0.127 -0.185 0.105  
ATOM   6475  N  NE2 . GLN C 1 52  ? -12.432 -18.801 40.986  1    113.19 ? 41  GLN C NE2 1 -0.114 -0.172 0.102  
ATOM   6476  N  N   . MET C 1 53  ? -18.073 -18.145 38.731  1    103.9  ? 42  MET C N   1 -0.166 -0.166 0.097  
ATOM   6477  C  CA  . MET C 1 53  ? -19.457 -17.785 38.45   1    103.94 ? 42  MET C CA  1 -0.178 -0.163 0.096  
ATOM   6478  C  C   . MET C 1 53  ? -20.204 -18.875 37.692  1    103.23 ? 42  MET C C   1 -0.185 -0.173 0.094  
ATOM   6479  O  O   . MET C 1 53  ? -21.353 -18.652 37.285  1    103.05 ? 42  MET C O   1 -0.196 -0.171 0.093  
ATOM   6480  C  CB  . MET C 1 53  ? -19.513 -16.448 37.703  1    99.81  ? 42  MET C CB  1 -0.179 -0.151 0.094  
ATOM   6481  C  CG  . MET C 1 53  ? -18.822 -15.304 38.472  1    112.24 ? 42  MET C CG  1 -0.172 -0.14  0.096  
ATOM   6482  S  SD  . MET C 1 53  ? -18.931 -13.672 37.687  1    112.06 ? 42  MET C SD  1 -0.173 -0.125 0.094  
ATOM   6483  C  CE  . MET C 1 53  ? -20.381 -13.921 36.69   1    105.55 ? 42  MET C CE  1 -0.187 -0.128 0.092  
ATOM   6484  N  N   . GLN C 1 54  ? -19.603 -20.055 37.524  1    100.58 ? 43  GLN C N   1 -0.18  -0.184 0.094  
ATOM   6485  C  CA  . GLN C 1 54  ? -20.288 -21.14  36.835  1    101.74 ? 43  GLN C CA  1 -0.186 -0.194 0.092  
ATOM   6486  C  C   . GLN C 1 54  ? -21.549 -21.552 37.584  1    102.57 ? 43  GLN C C   1 -0.197 -0.198 0.094  
ATOM   6487  O  O   . GLN C 1 54  ? -21.74  -21.243 38.758  1    108.44 ? 43  GLN C O   1 -0.199 -0.195 0.097  
ATOM   6488  C  CB  . GLN C 1 54  ? -19.388 -22.357 36.694  1    103.67 ? 43  GLN C CB  1 -0.178 -0.205 0.092  
ATOM   6489  C  CG  . GLN C 1 54  ? -18.109 -22.08  35.984  1    108.48 ? 43  GLN C CG  1 -0.166 -0.202 0.09   
ATOM   6490  C  CD  . GLN C 1 54  ? -17.463 -23.347 35.496  1    111.94 ? 43  GLN C CD  1 -0.16  -0.214 0.089  
ATOM   6491  O  OE1 . GLN C 1 54  ? -17.479 -24.378 36.181  1    103.37 ? 43  GLN C OE1 1 -0.16  -0.223 0.09   
ATOM   6492  N  NE2 . GLN C 1 54  ? -16.91  -23.293 34.282  1    116.92 ? 43  GLN C NE2 1 -0.155 -0.213 0.086  
ATOM   6493  N  N   . ARG C 1 55  ? -22.421 -22.265 36.877  1    104.43 ? 44  ARG C N   1 -0.205 -0.204 0.092  
ATOM   6494  C  CA  . ARG C 1 55  ? -23.683 -22.77  37.412  1    100.21 ? 44  ARG C CA  1 -0.217 -0.209 0.093  
ATOM   6495  C  C   . ARG C 1 55  ? -24.613 -21.651 37.872  1    99.54  ? 44  ARG C C   1 -0.226 -0.198 0.095  
ATOM   6496  O  O   . ARG C 1 55  ? -25.803 -21.895 38.093  1    104.78 ? 44  ARG C O   1 -0.236 -0.201 0.095  
ATOM   6497  C  CB  . ARG C 1 55  ? -23.43  -23.747 38.561  1    108.3  ? 44  ARG C CB  1 -0.215 -0.218 0.096  
ATOM   6498  C  CG  . ARG C 1 55  ? -22.197 -24.639 38.389  1    113.66 ? 44  ARG C CG  1 -0.203 -0.226 0.096  
ATOM   6499  C  CD  . ARG C 1 55  ? -22.477 -25.868 37.528  1    114.61 ? 44  ARG C CD  1 -0.206 -0.237 0.094  
ATOM   6500  N  NE  . ARG C 1 55  ? -21.291 -26.715 37.431  1    120.35 ? 44  ARG C NE  1 -0.195 -0.245 0.093  
ATOM   6501  C  CZ  . ARG C 1 55  ? -20.796 -27.202 36.298  1    122.09 ? 44  ARG C CZ  1 -0.191 -0.249 0.091  
ATOM   6502  N  NH1 . ARG C 1 55  ? -21.41  -27.024 35.137  1    110.96 ? 44  ARG C NH1 1 -0.196 -0.248 0.088  
ATOM   6503  N  NH2 . ARG C 1 55  ? -19.661 -27.899 36.334  1    123.79 ? 44  ARG C NH2 1 -0.18  -0.256 0.091  
ATOM   6504  N  N   . MET C 1 56  ? -24.104 -20.431 37.996  1    97.08  ? 45  MET C N   1 -0.221 -0.187 0.095  
ATOM   6505  C  CA  . MET C 1 56  ? -24.916 -19.312 38.467  1    104.27 ? 45  MET C CA  1 -0.228 -0.177 0.096  
ATOM   6506  C  C   . MET C 1 56  ? -25.926 -18.919 37.4    1    104.02 ? 45  MET C C   1 -0.238 -0.173 0.093  
ATOM   6507  O  O   . MET C 1 56  ? -25.533 -18.313 36.396  1    100.98 ? 45  MET C O   1 -0.234 -0.168 0.091  
ATOM   6508  C  CB  . MET C 1 56  ? -24.03  -18.116 38.83   1    104.9  ? 45  MET C CB  1 -0.22  -0.166 0.097  
ATOM   6509  C  CG  . MET C 1 56  ? -23.065 -18.381 39.993  1    110.82 ? 45  MET C CG  1 -0.211 -0.168 0.1    
ATOM   6510  S  SD  . MET C 1 56  ? -22.685 -16.948 41.047  1    115.87 ? 45  MET C SD  1 -0.208 -0.155 0.102  
ATOM   6511  C  CE  . MET C 1 56  ? -24.336 -16.309 41.376  1    101.46 ? 45  MET C CE  1 -0.223 -0.149 0.103  
ATOM   6512  N  N   . PRO C 1 57  ? -27.223 -19.168 37.601  1    103.44 ? 46  PRO C N   1 -0.249 -0.176 0.094  
ATOM   6513  C  CA  . PRO C 1 57  ? -28.163 -19.176 36.475  1    104.32 ? 46  PRO C CA  1 -0.258 -0.176 0.091  
ATOM   6514  C  C   . PRO C 1 57  ? -28.279 -17.81  35.809  1    112.24 ? 46  PRO C C   1 -0.259 -0.163 0.089  
ATOM   6515  O  O   . PRO C 1 57  ? -28.221 -16.77  36.474  1    112.62 ? 46  PRO C O   1 -0.259 -0.154 0.091  
ATOM   6516  C  CB  . PRO C 1 57  ? -29.48  -19.592 37.13   1    98.9   ? 46  PRO C CB  1 -0.27  -0.18  0.093  
ATOM   6517  C  CG  . PRO C 1 57  ? -29.378 -19.006 38.5    1    108.64 ? 46  PRO C CG  1 -0.269 -0.174 0.096  
ATOM   6518  C  CD  . PRO C 1 57  ? -27.923 -19.127 38.894  1    103.88 ? 46  PRO C CD  1 -0.256 -0.175 0.097  
ATOM   6519  N  N   . ALA C 1 58  ? -28.456 -17.821 34.476  1    105.11 ? 47  ALA C N   1 -0.261 -0.163 0.086  
ATOM   6520  C  CA  . ALA C 1 58  ? -28.578 -16.577 33.739  1    103.54 ? 47  ALA C CA  1 -0.262 -0.152 0.084  
ATOM   6521  C  C   . ALA C 1 58  ? -29.872 -16.42  32.95   1    107.02 ? 47  ALA C C   1 -0.274 -0.15  0.082  
ATOM   6522  O  O   . ALA C 1 58  ? -30.187 -15.295 32.561  1    108.46 ? 47  ALA C O   1 -0.277 -0.14  0.081  
ATOM   6523  C  CB  . ALA C 1 58  ? -27.386 -16.395 32.787  1    103.8  ? 47  ALA C CB  1 -0.251 -0.15  0.082  
ATOM   6524  N  N   . GLY C 1 59  ? -30.66  -17.474 32.744  1    101.44 ? 48  GLY C N   1 -0.281 -0.16  0.082  
ATOM   6525  C  CA  . GLY C 1 59  ? -31.92  -17.296 32.031  1    115.17 ? 48  GLY C CA  1 -0.293 -0.159 0.08   
ATOM   6526  C  C   . GLY C 1 59  ? -31.851 -17.273 30.504  1    114.58 ? 48  GLY C C   1 -0.292 -0.158 0.076  
ATOM   6527  O  O   . GLY C 1 59  ? -32.904 -17.366 29.848  1    107.81 ? 48  GLY C O   1 -0.302 -0.159 0.075  
ATOM   6528  N  N   . GLY C 1 60  ? -30.667 -17.117 29.913  1    109.64 ? 49  GLY C N   1 -0.281 -0.157 0.075  
ATOM   6529  C  CA  . GLY C 1 60  ? -30.438 -17.475 28.529  1    108.44 ? 49  GLY C CA  1 -0.279 -0.16  0.071  
ATOM   6530  C  C   . GLY C 1 60  ? -29.938 -18.903 28.429  1    111.88 ? 49  GLY C C   1 -0.274 -0.173 0.071  
ATOM   6531  O  O   . GLY C 1 60  ? -30.157 -19.73  29.32   1    108.78 ? 49  GLY C O   1 -0.276 -0.181 0.073  
ATOM   6532  N  N   . GLU C 1 61  ? -29.236 -19.193 27.328  1    104.41 ? 50  GLU C N   1 -0.268 -0.176 0.068  
ATOM   6533  C  CA  . GLU C 1 61  ? -28.638 -20.517 27.19   1    108.21 ? 50  GLU C CA  1 -0.262 -0.188 0.068  
ATOM   6534  C  C   . GLU C 1 61  ? -27.288 -20.642 27.901  1    112.58 ? 50  GLU C C   1 -0.25  -0.189 0.07   
ATOM   6535  O  O   . GLU C 1 61  ? -26.831 -21.768 28.132  1    115.23 ? 50  GLU C O   1 -0.246 -0.199 0.07   
ATOM   6536  C  CB  . GLU C 1 61  ? -28.523 -20.889 25.709  1    111.21 ? 50  GLU C CB  1 -0.261 -0.191 0.064  
ATOM   6537  C  CG  . GLU C 1 61  ? -29.899 -20.951 25.032  1    119.61 ? 50  GLU C CG  1 -0.274 -0.192 0.063  
ATOM   6538  C  CD  . GLU C 1 61  ? -29.903 -21.662 23.677  1    124.11 ? 50  GLU C CD  1 -0.274 -0.199 0.059  
ATOM   6539  O  OE1 . GLU C 1 61  ? -28.927 -21.508 22.901  1    120.1  ? 50  GLU C OE1 1 -0.265 -0.197 0.057  
ATOM   6540  O  OE2 . GLU C 1 61  ? -30.899 -22.376 23.394  1    123.6  ? 50  GLU C OE2 1 -0.283 -0.205 0.058  
ATOM   6541  N  N   . GLU C 1 62  ? -26.643 -19.532 28.265  1    106.81 ? 51  GLU C N   1 -0.244 -0.179 0.071  
ATOM   6542  C  CA  . GLU C 1 62  ? -25.435 -19.575 29.077  1    101    ? 51  GLU C CA  1 -0.233 -0.179 0.073  
ATOM   6543  C  C   . GLU C 1 62  ? -25.801 -19.307 30.518  1    103.72 ? 51  GLU C C   1 -0.236 -0.177 0.076  
ATOM   6544  O  O   . GLU C 1 62  ? -26.853 -18.733 30.809  1    103.11 ? 51  GLU C O   1 -0.246 -0.172 0.077  
ATOM   6545  C  CB  . GLU C 1 62  ? -24.402 -18.528 28.66   1    101.36 ? 51  GLU C CB  1 -0.224 -0.17  0.072  
ATOM   6546  C  CG  . GLU C 1 62  ? -24.118 -18.398 27.196  1    107.6  ? 51  GLU C CG  1 -0.221 -0.169 0.068  
ATOM   6547  C  CD  . GLU C 1 62  ? -23.586 -17.014 26.839  1    106.27 ? 51  GLU C CD  1 -0.216 -0.156 0.067  
ATOM   6548  O  OE1 . GLU C 1 62  ? -22.583 -16.941 26.08   1    104.46 ? 51  GLU C OE1 1 -0.207 -0.155 0.065  
ATOM   6549  O  OE2 . GLU C 1 62  ? -24.178 -16.009 27.321  1    101.44 ? 51  GLU C OE2 1 -0.222 -0.147 0.068  
ATOM   6550  N  N   . ASP C 1 63  ? -24.897 -19.702 31.417  1    103.43 ? 52  ASP C N   1 -0.228 -0.181 0.078  
ATOM   6551  C  CA  . ASP C 1 63  ? -24.962 -19.309 32.818  1    97.48  ? 52  ASP C CA  1 -0.229 -0.177 0.082  
ATOM   6552  C  C   . ASP C 1 63  ? -24.307 -17.935 32.957  1    101.02 ? 52  ASP C C   1 -0.223 -0.164 0.082  
ATOM   6553  O  O   . ASP C 1 63  ? -23.991 -17.273 31.964  1    104.83 ? 52  ASP C O   1 -0.22  -0.158 0.08   
ATOM   6554  C  CB  . ASP C 1 63  ? -24.322 -20.379 33.703  1    97.11  ? 52  ASP C CB  1 -0.223 -0.187 0.084  
ATOM   6555  C  CG  . ASP C 1 63  ? -22.859 -20.642 33.364  1    98.5   ? 52  ASP C CG  1 -0.209 -0.189 0.083  
ATOM   6556  O  OD1 . ASP C 1 63  ? -22.158 -19.714 32.911  1    99.14  ? 52  ASP C OD1 1 -0.203 -0.181 0.082  
ATOM   6557  O  OD2 . ASP C 1 63  ? -22.405 -21.795 33.552  1    96.17  ? 52  ASP C OD2 1 -0.205 -0.2   0.084  
ATOM   6558  N  N   . GLN C 1 64  ? -24.082 -17.481 34.188  1    103.13 ? 53  GLN C N   1 -0.221 -0.16  0.085  
ATOM   6559  C  CA  . GLN C 1 64  ? -23.486 -16.161 34.353  1    101.43 ? 53  GLN C CA  1 -0.215 -0.148 0.086  
ATOM   6560  C  C   . GLN C 1 64  ? -21.997 -16.169 34.042  1    97.68  ? 53  GLN C C   1 -0.202 -0.148 0.085  
ATOM   6561  O  O   . GLN C 1 64  ? -21.461 -15.144 33.614  1    100.78 ? 53  GLN C O   1 -0.197 -0.139 0.084  
ATOM   6562  C  CB  . GLN C 1 64  ? -23.737 -15.622 35.768  1    98.78  ? 53  GLN C CB  1 -0.218 -0.143 0.089  
ATOM   6563  C  CG  . GLN C 1 64  ? -25.155 -15.087 36.009  1    98.31  ? 53  GLN C CG  1 -0.231 -0.138 0.09   
ATOM   6564  C  CD  . GLN C 1 64  ? -25.453 -13.775 35.271  1    101.84 ? 53  GLN C CD  1 -0.233 -0.126 0.088  
ATOM   6565  O  OE1 . GLN C 1 64  ? -24.558 -13.136 34.687  1    97.23  ? 53  GLN C OE1 1 -0.225 -0.12  0.087  
ATOM   6566  N  NE2 . GLN C 1 64  ? -26.724 -13.364 35.305  1    97.58  ? 53  GLN C NE2 1 -0.245 -0.122 0.088  
ATOM   6567  N  N   . TYR C 1 65  ? -21.312 -17.3   34.222  1    94.18  ? 54  TYR C N   1 -0.195 -0.159 0.085  
ATOM   6568  C  CA  . TYR C 1 65  ? -19.875 -17.318 33.964  1    98.72  ? 54  TYR C CA  1 -0.182 -0.159 0.085  
ATOM   6569  C  C   . TYR C 1 65  ? -19.582 -17.05  32.493  1    103.38 ? 54  TYR C C   1 -0.179 -0.156 0.081  
ATOM   6570  O  O   . TYR C 1 65  ? -18.81  -16.145 32.161  1    101.15 ? 54  TYR C O   1 -0.172 -0.148 0.08   
ATOM   6571  C  CB  . TYR C 1 65  ? -19.264 -18.649 34.404  1    101.03 ? 54  TYR C CB  1 -0.177 -0.171 0.086  
ATOM   6572  C  CG  . TYR C 1 65  ? -17.92  -18.954 33.765  1    104.26 ? 54  TYR C CG  1 -0.164 -0.174 0.084  
ATOM   6573  C  CD1 . TYR C 1 65  ? -16.779 -18.257 34.134  1    101.88 ? 54  TYR C CD1 1 -0.154 -0.167 0.085  
ATOM   6574  C  CD2 . TYR C 1 65  ? -17.797 -19.941 32.789  1    109.85 ? 54  TYR C CD2 1 -0.163 -0.183 0.082  
ATOM   6575  C  CE1 . TYR C 1 65  ? -15.551 -18.534 33.56   1    106.41 ? 54  TYR C CE1 1 -0.143 -0.17  0.084  
ATOM   6576  C  CE2 . TYR C 1 65  ? -16.573 -20.226 32.208  1    112.63 ? 54  TYR C CE2 1 -0.152 -0.185 0.08   
ATOM   6577  C  CZ  . TYR C 1 65  ? -15.449 -19.519 32.595  1    111.83 ? 54  TYR C CZ  1 -0.142 -0.179 0.081  
ATOM   6578  O  OH  . TYR C 1 65  ? -14.225 -19.802 32.01   1    107.32 ? 54  TYR C OH  1 -0.13  -0.181 0.08   
ATOM   6579  N  N   . LEU C 1 66  ? -20.208 -17.814 31.596  1    97.98  ? 55  LEU C N   1 -0.185 -0.163 0.079  
ATOM   6580  C  CA  . LEU C 1 66  ? -20.007 -17.594 30.165  1    102.09 ? 55  LEU C CA  1 -0.183 -0.161 0.075  
ATOM   6581  C  C   . LEU C 1 66  ? -20.448 -16.194 29.747  1    98.94  ? 55  LEU C C   1 -0.187 -0.148 0.074  
ATOM   6582  O  O   . LEU C 1 66  ? -19.706 -15.464 29.073  1    89.93  ? 55  LEU C O   1 -0.181 -0.142 0.073  
ATOM   6583  C  CB  . LEU C 1 66  ? -20.767 -18.652 29.365  1    98.57  ? 55  LEU C CB  1 -0.19  -0.171 0.073  
ATOM   6584  C  CG  . LEU C 1 66  ? -20.201 -20.064 29.431  1    97.43  ? 55  LEU C CG  1 -0.185 -0.184 0.073  
ATOM   6585  C  CD1 . LEU C 1 66  ? -20.88  -20.876 28.392  1    100.48 ? 55  LEU C CD1 1 -0.191 -0.191 0.071  
ATOM   6586  C  CD2 . LEU C 1 66  ? -18.667 -20.058 29.278  1    102.12 ? 55  LEU C CD2 1 -0.171 -0.184 0.073  
ATOM   6587  N  N   . ARG C 1 67  ? -21.664 -15.812 30.131  1    97.53  ? 56  ARG C N   1 -0.199 -0.145 0.075  
ATOM   6588  C  CA  . ARG C 1 67  ? -22.198 -14.511 29.756  1    95.57  ? 56  ARG C CA  1 -0.203 -0.133 0.074  
ATOM   6589  C  C   . ARG C 1 67  ? -21.251 -13.386 30.155  1    97.84  ? 56  ARG C C   1 -0.195 -0.123 0.075  
ATOM   6590  O  O   . ARG C 1 67  ? -20.768 -12.641 29.296  1    98.87  ? 56  ARG C O   1 -0.19  -0.116 0.073  
ATOM   6591  C  CB  . ARG C 1 67  ? -23.572 -14.346 30.39   1    97.26  ? 56  ARG C CB  1 -0.216 -0.131 0.076  
ATOM   6592  C  CG  . ARG C 1 67  ? -24.018 -12.941 30.654  1    98.83  ? 56  ARG C CG  1 -0.22  -0.119 0.077  
ATOM   6593  C  CD  . ARG C 1 67  ? -25.499 -13.001 30.894  1    103.04 ? 56  ARG C CD  1 -0.234 -0.119 0.077  
ATOM   6594  N  NE  . ARG C 1 67  ? -25.967 -12.054 31.89   1    103.82 ? 56  ARG C NE  1 -0.238 -0.11  0.08   
ATOM   6595  C  CZ  . ARG C 1 67  ? -26.389 -10.834 31.597  1    107.43 ? 56  ARG C CZ  1 -0.242 -0.099 0.079  
ATOM   6596  N  NH1 . ARG C 1 67  ? -26.334 -10.368 30.363  1    110.43 ? 56  ARG C NH1 1 -0.241 -0.095 0.076  
ATOM   6597  N  NH2 . ARG C 1 67  ? -26.89  -10.07  32.563  1    114.31 ? 56  ARG C NH2 1 -0.246 -0.092 0.081  
ATOM   6598  N  N   . ILE C 1 68  ? -20.941 -13.272 31.455  1    98.74  ? 57  ILE C N   1 -0.192 -0.122 0.079  
ATOM   6599  C  CA  . ILE C 1 68  ? -20.008 -12.24  31.921  1    99.12  ? 57  ILE C CA  1 -0.183 -0.112 0.08   
ATOM   6600  C  C   . ILE C 1 68  ? -18.661 -12.378 31.213  1    96.42  ? 57  ILE C C   1 -0.171 -0.113 0.078  
ATOM   6601  O  O   . ILE C 1 68  ? -18.125 -11.399 30.676  1    93.03  ? 57  ILE C O   1 -0.166 -0.104 0.077  
ATOM   6602  C  CB  . ILE C 1 68  ? -19.854 -12.283 33.461  1    100.85 ? 57  ILE C CB  1 -0.182 -0.113 0.084  
ATOM   6603  C  CG1 . ILE C 1 68  ? -21.022 -11.582 34.164  1    92.46  ? 57  ILE C CG1 1 -0.193 -0.106 0.085  
ATOM   6604  C  CG2 . ILE C 1 68  ? -18.564 -11.585 33.919  1    91.07  ? 57  ILE C CG2 1 -0.17  -0.106 0.085  
ATOM   6605  C  CD1 . ILE C 1 68  ? -20.881 -10.079 34.177  1    92.94  ? 57  ILE C CD1 1 -0.191 -0.092 0.085  
ATOM   6606  N  N   . LYS C 1 69  ? -18.102 -13.597 31.191  1    98.74  ? 58  LYS C N   1 -0.166 -0.125 0.078  
ATOM   6607  C  CA  . LYS C 1 69  ? -16.811 -13.83  30.537  1    98.33  ? 58  LYS C CA  1 -0.154 -0.127 0.076  
ATOM   6608  C  C   . LYS C 1 69  ? -16.765 -13.224 29.147  1    98.44  ? 58  LYS C C   1 -0.154 -0.121 0.073  
ATOM   6609  O  O   . LYS C 1 69  ? -15.818 -12.502 28.81   1    100.83 ? 58  LYS C O   1 -0.145 -0.115 0.072  
ATOM   6610  C  CB  . LYS C 1 69  ? -16.512 -15.321 30.441  1    98.68  ? 58  LYS C CB  1 -0.151 -0.14  0.076  
ATOM   6611  C  CG  . LYS C 1 69  ? -15.206 -15.657 29.742  1    87.81  ? 58  LYS C CG  1 -0.139 -0.143 0.074  
ATOM   6612  C  CD  . LYS C 1 69  ? -15.218 -17.136 29.364  1    95.1   ? 58  LYS C CD  1 -0.139 -0.157 0.073  
ATOM   6613  C  CE  . LYS C 1 69  ? -13.881 -17.628 28.82   1    98.78  ? 58  LYS C CE  1 -0.127 -0.162 0.072  
ATOM   6614  N  NZ  . LYS C 1 69  ? -13.993 -18.95  28.096  1    103.1  ? 58  LYS C NZ  1 -0.128 -0.174 0.07   
ATOM   6615  N  N   . HIS C 1 70  ? -17.78  -13.508 28.32   1    98.8   ? 59  HIS C N   1 -0.163 -0.124 0.071  
ATOM   6616  C  CA  . HIS C 1 70  ? -17.765 -13.005 26.943  1    100.13 ? 59  HIS C CA  1 -0.163 -0.119 0.067  
ATOM   6617  C  C   . HIS C 1 70  ? -17.697 -11.487 26.921  1    97.99  ? 59  HIS C C   1 -0.162 -0.105 0.067  
ATOM   6618  O  O   . HIS C 1 70  ? -16.731 -10.909 26.409  1    100.86 ? 59  HIS C O   1 -0.153 -0.1   0.066  
ATOM   6619  C  CB  . HIS C 1 70  ? -18.976 -13.515 26.152  1    93.69  ? 59  HIS C CB  1 -0.174 -0.124 0.065  
ATOM   6620  C  CG  . HIS C 1 70  ? -18.94  -14.991 25.903  1    96.93  ? 59  HIS C CG  1 -0.174 -0.137 0.065  
ATOM   6621  N  ND1 . HIS C 1 70  ? -20.078 -15.771 25.868  1    97.47  ? 59  HIS C ND1 1 -0.184 -0.145 0.065  
ATOM   6622  C  CD2 . HIS C 1 70  ? -17.896 -15.836 25.713  1    95.55  ? 59  HIS C CD2 1 -0.164 -0.145 0.064  
ATOM   6623  C  CE1 . HIS C 1 70  ? -19.736 -17.033 25.669  1    99.53  ? 59  HIS C CE1 1 -0.181 -0.156 0.064  
ATOM   6624  N  NE2 . HIS C 1 70  ? -18.42  -17.098 25.563  1    100.78 ? 59  HIS C NE2 1 -0.169 -0.157 0.064  
ATOM   6625  N  N   . MET C 1 71  ? -18.699 -10.822 27.501  1    91.91  ? 60  MET C N   1 -0.171 -0.099 0.069  
ATOM   6626  C  CA  . MET C 1 71  ? -18.72  -9.367  27.448  1    90.99  ? 60  MET C CA  1 -0.172 -0.086 0.069  
ATOM   6627  C  C   . MET C 1 71  ? -17.405 -8.768  27.946  1    97.38  ? 60  MET C C   1 -0.16  -0.08  0.07   
ATOM   6628  O  O   . MET C 1 71  ? -16.921 -7.776  27.385  1    97.21  ? 60  MET C O   1 -0.155 -0.071 0.068  
ATOM   6629  C  CB  . MET C 1 71  ? -19.911 -8.839  28.234  1    91.15  ? 60  MET C CB  1 -0.182 -0.081 0.07   
ATOM   6630  C  CG  . MET C 1 71  ? -21.181 -9.614  27.973  1    92.77  ? 60  MET C CG  1 -0.194 -0.088 0.07   
ATOM   6631  S  SD  . MET C 1 71  ? -22.593 -8.872  28.802  1    98.29  ? 60  MET C SD  1 -0.207 -0.081 0.072  
ATOM   6632  C  CE  . MET C 1 71  ? -21.771 -8.068  30.162  1    97.15  ? 60  MET C CE  1 -0.2   -0.074 0.075  
ATOM   6633  N  N   . SER C 1 72  ? -16.781 -9.387  28.959  1    96.7   ? 61  SER C N   1 -0.154 -0.086 0.072  
ATOM   6634  C  CA  . SER C 1 72  ? -15.473 -8.91   29.414  1    101.98 ? 61  SER C CA  1 -0.142 -0.082 0.073  
ATOM   6635  C  C   . SER C 1 72  ? -14.423 -9.032  28.315  1    101.76 ? 61  SER C C   1 -0.132 -0.083 0.071  
ATOM   6636  O  O   . SER C 1 72  ? -13.614 -8.117  28.11   1    100.71 ? 61  SER C O   1 -0.125 -0.074 0.07   
ATOM   6637  C  CB  . SER C 1 72  ? -15.004 -9.684  30.65   1    100.66 ? 61  SER C CB  1 -0.137 -0.089 0.077  
ATOM   6638  O  OG  . SER C 1 72  ? -15.947 -9.654  31.702  1    100.79 ? 61  SER C OG  1 -0.146 -0.088 0.079  
ATOM   6639  N  N   . ALA C 1 73  ? -14.407 -10.161 27.606  1    99.97  ? 62  ALA C N   1 -0.132 -0.093 0.069  
ATOM   6640  C  CA  . ALA C 1 73  ? -13.397 -10.368 26.577  1    102.57 ? 62  ALA C CA  1 -0.123 -0.095 0.066  
ATOM   6641  C  C   . ALA C 1 73  ? -13.527 -9.367  25.43   1    107.47 ? 62  ALA C C   1 -0.124 -0.086 0.063  
ATOM   6642  O  O   . ALA C 1 73  ? -12.541 -9.101  24.728  1    108.24 ? 62  ALA C O   1 -0.115 -0.083 0.062  
ATOM   6643  C  CB  . ALA C 1 73  ? -13.477 -11.808 26.07   1    95.46  ? 62  ALA C CB  1 -0.124 -0.108 0.065  
ATOM   6644  N  N   . LEU C 1 74  ? -14.71  -8.787  25.247  1    106.36 ? 63  LEU C N   1 -0.135 -0.081 0.063  
ATOM   6645  C  CA  . LEU C 1 74  ? -14.907 -7.752  24.24   1    98.79  ? 63  LEU C CA  1 -0.137 -0.071 0.061  
ATOM   6646  C  C   . LEU C 1 74  ? -14.502 -6.385  24.768  1    105.55 ? 63  LEU C C   1 -0.133 -0.059 0.062  
ATOM   6647  O  O   . LEU C 1 74  ? -13.779 -5.653  24.089  1    112.35 ? 63  LEU C O   1 -0.126 -0.052 0.06   
ATOM   6648  C  CB  . LEU C 1 74  ? -16.362 -7.741  23.791  1    97.07  ? 63  LEU C CB  1 -0.15  -0.071 0.059  
ATOM   6649  C  CG  . LEU C 1 74  ? -16.819 -6.707  22.785  1    103.02 ? 63  LEU C CG  1 -0.154 -0.061 0.057  
ATOM   6650  C  CD1 . LEU C 1 74  ? -15.759 -6.477  21.682  1    116.43 ? 63  LEU C CD1 1 -0.144 -0.059 0.054  
ATOM   6651  C  CD2 . LEU C 1 74  ? -18.133 -7.229  22.207  1    107.87 ? 63  LEU C CD2 1 -0.166 -0.066 0.055  
ATOM   6652  N  N   . ILE C 1 75  ? -14.973 -6.017  25.97   1    103.74 ? 64  ILE C N   1 -0.137 -0.055 0.065  
ATOM   6653  C  CA  . ILE C 1 75  ? -14.507 -4.792  26.626  1    103.58 ? 64  ILE C CA  1 -0.133 -0.044 0.066  
ATOM   6654  C  C   . ILE C 1 75  ? -12.984 -4.703  26.563  1    103.44 ? 64  ILE C C   1 -0.119 -0.043 0.066  
ATOM   6655  O  O   . ILE C 1 75  ? -12.419 -3.631  26.316  1    105.36 ? 64  ILE C O   1 -0.114 -0.033 0.066  
ATOM   6656  C  CB  . ILE C 1 75  ? -15.03  -4.725  28.082  1    101.13 ? 64  ILE C CB  1 -0.138 -0.043 0.07   
ATOM   6657  C  CG1 . ILE C 1 75  ? -16.44  -4.122  28.127  1    98.01  ? 64  ILE C CG1 1 -0.151 -0.038 0.07   
ATOM   6658  C  CG2 . ILE C 1 75  ? -14.1   -3.907  28.973  1    87.81  ? 64  ILE C CG2 1 -0.129 -0.036 0.072  
ATOM   6659  C  CD1 . ILE C 1 75  ? -17.335 -4.722  29.169  1    92.58  ? 64  ILE C CD1 1 -0.159 -0.043 0.073  
ATOM   6660  N  N   . LYS C 1 76  ? -12.3   -5.837  26.747  1    101.43 ? 65  LYS C N   1 -0.113 -0.053 0.067  
ATOM   6661  C  CA  . LYS C 1 76  ? -10.84  -5.845  26.718  1    103.01 ? 65  LYS C CA  1 -0.099 -0.054 0.067  
ATOM   6662  C  C   . LYS C 1 76  ? -10.317 -5.654  25.303  1    113.84 ? 65  LYS C C   1 -0.095 -0.052 0.063  
ATOM   6663  O  O   . LYS C 1 76  ? -9.376  -4.881  25.083  1    118.4  ? 65  LYS C O   1 -0.086 -0.045 0.063  
ATOM   6664  C  CB  . LYS C 1 76  ? -10.308 -7.153  27.314  1    111.23 ? 65  LYS C CB  1 -0.094 -0.066 0.068  
ATOM   6665  C  CG  . LYS C 1 76  ? -10.607 -7.339  28.809  1    104.42 ? 65  LYS C CG  1 -0.097 -0.067 0.072  
ATOM   6666  C  CD  . LYS C 1 76  ? -10.635 -8.807  29.231  1    102.46 ? 65  LYS C CD  1 -0.097 -0.081 0.073  
ATOM   6667  C  CE  . LYS C 1 76  ? -9.23   -9.415  29.286  1    112.59 ? 65  LYS C CE  1 -0.085 -0.086 0.073  
ATOM   6668  N  NZ  . LYS C 1 76  ? -9.109  -10.611 30.208  1    103.39 ? 65  LYS C NZ  1 -0.083 -0.097 0.075  
ATOM   6669  N  N   . LYS C 1 77  ? -10.909 -6.356  24.332  1    119.44 ? 66  LYS C N   1 -0.1   -0.058 0.061  
ATOM   6670  C  CA  . LYS C 1 77  ? -10.498 -6.215  22.937  1    112.61 ? 66  LYS C CA  1 -0.096 -0.057 0.057  
ATOM   6671  C  C   . LYS C 1 77  ? -10.632 -4.769  22.468  1    116.27 ? 66  LYS C C   1 -0.097 -0.044 0.056  
ATOM   6672  O  O   . LYS C 1 77  ? -9.708  -4.211  21.866  1    119.92 ? 66  LYS C O   1 -0.089 -0.039 0.055  
ATOM   6673  C  CB  . LYS C 1 77  ? -11.329 -7.158  22.062  1    113.16 ? 66  LYS C CB  1 -0.104 -0.066 0.055  
ATOM   6674  C  CG  . LYS C 1 77  ? -10.948 -7.171  20.592  1    122.52 ? 66  LYS C CG  1 -0.1   -0.066 0.051  
ATOM   6675  C  CD  . LYS C 1 77  ? -9.496  -7.621  20.391  1    125.48 ? 66  LYS C CD  1 -0.087 -0.07  0.051  
ATOM   6676  C  CE  . LYS C 1 77  ? -8.992  -7.276  18.997  1    120.72 ? 66  LYS C CE  1 -0.082 -0.067 0.047  
ATOM   6677  N  NZ  . LYS C 1 77  ? -9.092  -5.807  18.699  1    119.54 ? 66  LYS C NZ  1 -0.083 -0.053 0.047  
ATOM   6678  N  N   . TYR C 1 78  ? -11.77  -4.136  22.77   1    116.73 ? 67  TYR C N   1 -0.108 -0.038 0.057  
ATOM   6679  C  CA  . TYR C 1 78  ? -12.092 -2.799  22.28   1    117.33 ? 67  TYR C CA  1 -0.111 -0.026 0.056  
ATOM   6680  C  C   . TYR C 1 78  ? -11.023 -1.799  22.698  1    119.48 ? 67  TYR C C   1 -0.101 -0.016 0.057  
ATOM   6681  O  O   . TYR C 1 78  ? -10.998 -1.35   23.851  1    118.94 ? 67  TYR C O   1 -0.101 -0.012 0.06   
ATOM   6682  C  CB  . TYR C 1 78  ? -13.476 -2.356  22.783  1    108.87 ? 67  TYR C CB  1 -0.123 -0.022 0.057  
ATOM   6683  C  CG  . TYR C 1 78  ? -14.058 -1.147  22.076  1    108.64 ? 67  TYR C CG  1 -0.129 -0.011 0.055  
ATOM   6684  C  CD1 . TYR C 1 78  ? -13.476 0.108   22.216  1    112.73 ? 67  TYR C CD1 1 -0.123 0.001  0.055  
ATOM   6685  C  CD2 . TYR C 1 78  ? -15.203 -1.257  21.287  1    106.28 ? 67  TYR C CD2 1 -0.139 -0.012 0.053  
ATOM   6686  C  CE1 . TYR C 1 78  ? -13.996 1.224   21.58   1    115.89 ? 67  TYR C CE1 1 -0.128 0.011  0.054  
ATOM   6687  C  CE2 . TYR C 1 78  ? -15.748 -0.141  20.647  1    107.34 ? 67  TYR C CE2 1 -0.144 -0.001 0.052  
ATOM   6688  C  CZ  . TYR C 1 78  ? -15.134 1.107   20.794  1    115.71 ? 67  TYR C CZ  1 -0.139 0.01   0.052  
ATOM   6689  O  OH  . TYR C 1 78  ? -15.649 2.241   20.168  1    110.99 ? 67  TYR C OH  1 -0.143 0.021  0.05   
ATOM   6690  N  N   . GLY C 1 79  ? -10.142 -1.464  21.751  1    125.93 ? 68  GLY C N   1 -0.093 -0.013 0.054  
ATOM   6691  C  CA  . GLY C 1 79  ? -9.11   -0.45   21.896  1    133.69 ? 68  GLY C CA  1 -0.083 -0.004 0.055  
ATOM   6692  C  C   . GLY C 1 79  ? -8.606  -0.197  23.304  1    130.54 ? 68  GLY C C   1 -0.079 -0.002 0.058  
ATOM   6693  O  O   . GLY C 1 79  ? -8.281  -1.138  24.036  1    127.76 ? 68  GLY C O   1 -0.076 -0.01  0.06   
ATOM   6694  N  N   . ASP C 1 80  ? -8.546  1.07    23.696  1    128.75 ? 69  ASP C N   1 -0.078 0.01   0.059  
ATOM   6695  C  CA  . ASP C 1 80  ? -8.078  1.456   25.024  1    129.36 ? 69  ASP C CA  1 -0.074 0.013  0.062  
ATOM   6696  C  C   . ASP C 1 80  ? -9.241  2.113   25.756  1    126.57 ? 69  ASP C C   1 -0.085 0.019  0.064  
ATOM   6697  O  O   . ASP C 1 80  ? -9.534  3.298   25.557  1    123.41 ? 69  ASP C O   1 -0.087 0.03   0.064  
ATOM   6698  C  CB  . ASP C 1 80  ? -6.875  2.384   24.936  1    134.44 ? 69  ASP C CB  1 -0.063 0.022  0.062  
ATOM   6699  C  CG  . ASP C 1 80  ? -7.127  3.573   24.036  1    144.23 ? 69  ASP C CG  1 -0.065 0.033  0.06   
ATOM   6700  O  OD1 . ASP C 1 80  ? -7.963  3.446   23.107  1    140.15 ? 69  ASP C OD1 1 -0.073 0.032  0.058  
ATOM   6701  O  OD2 . ASP C 1 80  ? -6.497  4.63    24.269  1    149.1  ? 69  ASP C OD2 1 -0.06  0.042  0.061  
ATOM   6702  N  N   . LEU C 1 81  ? -9.903  1.335   26.587  1    122.75 ? 70  LEU C N   1 -0.091 0.012  0.066  
ATOM   6703  C  CA  . LEU C 1 81  ? -10.909 1.855   27.479  1    119.31 ? 70  LEU C CA  1 -0.1   0.017  0.069  
ATOM   6704  C  C   . LEU C 1 81  ? -10.378 1.87    28.91   1    112.46 ? 70  LEU C C   1 -0.095 0.017  0.072  
ATOM   6705  O  O   . LEU C 1 81  ? -9.508  1.068   29.264  1    112.58 ? 70  LEU C O   1 -0.087 0.01   0.073  
ATOM   6706  C  CB  . LEU C 1 81  ? -12.177 0.999   27.387  1    120.41 ? 70  LEU C CB  1 -0.112 0.009  0.068  
ATOM   6707  C  CG  . LEU C 1 81  ? -12.882 1.091   26.033  1    106.19 ? 70  LEU C CG  1 -0.118 0.01   0.065  
ATOM   6708  C  CD1 . LEU C 1 81  ? -13.94  0.004   25.896  1    103.97 ? 70  LEU C CD1 1 -0.128 0.0    0.065  
ATOM   6709  C  CD2 . LEU C 1 81  ? -13.5   2.47    25.912  1    100.45 ? 70  LEU C CD2 1 -0.124 0.023  0.065  
ATOM   6710  N  N   . PRO C 1 82  ? -10.833 2.794   29.737  1    112.57 ? 71  PRO C N   1 -0.099 0.026  0.074  
ATOM   6711  C  CA  . PRO C 1 82  ? -10.393 2.802   31.146  1    111.05 ? 71  PRO C CA  1 -0.095 0.026  0.078  
ATOM   6712  C  C   . PRO C 1 82  ? -10.936 1.611   31.942  1    107.87 ? 71  PRO C C   1 -0.1   0.015  0.08   
ATOM   6713  O  O   . PRO C 1 82  ? -11.923 1.73    32.681  1    99.3   ? 71  PRO C O   1 -0.109 0.016  0.082  
ATOM   6714  C  CB  . PRO C 1 82  ? -10.932 4.142   31.675  1    106.42 ? 71  PRO C CB  1 -0.1   0.038  0.079  
ATOM   6715  C  CG  . PRO C 1 82  ? -12.07  4.494   30.754  1    116.57 ? 71  PRO C CG  1 -0.111 0.041  0.077  
ATOM   6716  C  CD  . PRO C 1 82  ? -11.667 3.957   29.391  1    111.63 ? 71  PRO C CD  1 -0.107 0.036  0.073  
ATOM   6717  N  N   . VAL C 1 83  ? -10.29  0.45    31.798  1    111    ? 72  VAL C N   1 -0.094 0.004  0.079  
ATOM   6718  C  CA  . VAL C 1 83  ? -10.814 -0.824  32.294  1    110.74 ? 72  VAL C CA  1 -0.099 -0.008 0.081  
ATOM   6719  C  C   . VAL C 1 83  ? -10.145 -1.166  33.62   1    107.81 ? 72  VAL C C   1 -0.093 -0.011 0.084  
ATOM   6720  O  O   . VAL C 1 83  ? -8.91   -1.203  33.714  1    107    ? 72  VAL C O   1 -0.082 -0.011 0.084  
ATOM   6721  C  CB  . VAL C 1 83  ? -10.615 -1.952  31.26   1    109.01 ? 72  VAL C CB  1 -0.097 -0.018 0.078  
ATOM   6722  C  CG1 . VAL C 1 83  ? -9.189  -1.938  30.701  1    113.22 ? 72  VAL C CG1 1 -0.084 -0.018 0.077  
ATOM   6723  C  CG2 . VAL C 1 83  ? -10.941 -3.325  31.875  1    98.16  ? 72  VAL C CG2 1 -0.1   -0.03  0.08   
ATOM   6724  N  N   . ILE C 1 84  ? -10.965 -1.427  34.644  1    109.49 ? 73  ILE C N   1 -0.1   -0.013 0.086  
ATOM   6725  C  CA  . ILE C 1 84  ? -10.505 -1.76   35.992  1    108.59 ? 73  ILE C CA  1 -0.096 -0.016 0.09   
ATOM   6726  C  C   . ILE C 1 84  ? -11.13  -3.09   36.404  1    104.36 ? 73  ILE C C   1 -0.102 -0.028 0.091  
ATOM   6727  O  O   . ILE C 1 84  ? -12.308 -3.35   36.122  1    104.99 ? 73  ILE C O   1 -0.113 -0.031 0.09   
ATOM   6728  C  CB  . ILE C 1 84  ? -10.857 -0.642  36.996  1    103.64 ? 73  ILE C CB  1 -0.099 -0.006 0.092  
ATOM   6729  C  CG1 . ILE C 1 84  ? -12.34  -0.697  37.378  1    105.92 ? 73  ILE C CG1 1 -0.113 -0.006 0.093  
ATOM   6730  C  CG2 . ILE C 1 84  ? -10.571 0.715   36.364  1    101.44 ? 73  ILE C CG2 1 -0.097 0.007  0.091  
ATOM   6731  C  CD1 . ILE C 1 84  ? -12.711 0.063   38.644  1    107.96 ? 73  ILE C CD1 1 -0.116 0.001  0.096  
ATOM   6732  N  N   . THR C 1 85  ? -10.337 -3.951  37.03   1    100.85 ? 74  THR C N   1 -0.095 -0.036 0.092  
ATOM   6733  C  CA  . THR C 1 85  ? -10.848 -5.259  37.409  1    106.1  ? 74  THR C CA  1 -0.099 -0.048 0.093  
ATOM   6734  C  C   . THR C 1 85  ? -11.052 -5.313  38.914  1    109.85 ? 74  THR C C   1 -0.101 -0.049 0.097  
ATOM   6735  O  O   . THR C 1 85  ? -10.496 -4.512  39.667  1    115.18 ? 74  THR C O   1 -0.096 -0.041 0.099  
ATOM   6736  C  CB  . THR C 1 85  ? -9.914  -6.396  36.957  1    106.8  ? 74  THR C CB  1 -0.091 -0.059 0.092  
ATOM   6737  O  OG1 . THR C 1 85  ? -8.687  -6.354  37.7    1    111.85 ? 74  THR C OG1 1 -0.08  -0.058 0.094  
ATOM   6738  C  CG2 . THR C 1 85  ? -9.618  -6.282  35.459  1    100.37 ? 74  THR C CG2 1 -0.088 -0.058 0.089  
ATOM   6739  N  N   . THR C 1 86  ? -11.887 -6.254  39.348  1    107.69 ? 75  THR C N   1 -0.109 -0.057 0.098  
ATOM   6740  C  CA  . THR C 1 86  ? -12.015 -6.492  40.777  1    107.7  ? 75  THR C CA  1 -0.11  -0.059 0.102  
ATOM   6741  C  C   . THR C 1 86  ? -10.728 -7.036  41.381  1    112.89 ? 75  THR C C   1 -0.098 -0.064 0.103  
ATOM   6742  O  O   . THR C 1 86  ? -10.506 -6.866  42.583  1    118.34 ? 75  THR C O   1 -0.096 -0.063 0.106  
ATOM   6743  C  CB  . THR C 1 86  ? -13.168 -7.452  41.049  1    104.68 ? 75  THR C CB  1 -0.121 -0.068 0.102  
ATOM   6744  O  OG1 . THR C 1 86  ? -13.087 -8.571  40.152  1    99.29  ? 75  THR C OG1 1 -0.12  -0.079 0.1    
ATOM   6745  C  CG2 . THR C 1 86  ? -14.506 -6.729  40.886  1    105.61 ? 75  THR C CG2 1 -0.133 -0.062 0.102  
ATOM   6746  N  N   . GLN C 1 87  ? -9.867  -7.66   40.572  1    109.43 ? 76  GLN C N   1 -0.09  -0.07  0.101  
ATOM   6747  C  CA  . GLN C 1 87  ? -8.624  -8.227  41.092  1    118.19 ? 76  GLN C CA  1 -0.079 -0.075 0.103  
ATOM   6748  C  C   . GLN C 1 87  ? -7.735  -7.177  41.743  1    122.05 ? 76  GLN C C   1 -0.071 -0.066 0.104  
ATOM   6749  O  O   . GLN C 1 87  ? -6.979  -7.496  42.669  1    124.44 ? 76  GLN C O   1 -0.064 -0.069 0.107  
ATOM   6750  C  CB  . GLN C 1 87  ? -7.857  -8.928  39.971  1    120.53 ? 76  GLN C CB  1 -0.072 -0.082 0.1    
ATOM   6751  C  CG  . GLN C 1 87  ? -6.763  -9.877  40.437  1    119.27 ? 76  GLN C CG  1 -0.062 -0.091 0.101  
ATOM   6752  C  CD  . GLN C 1 87  ? -5.386  -9.277  40.277  1    127.98 ? 76  GLN C CD  1 -0.049 -0.085 0.101  
ATOM   6753  O  OE1 . GLN C 1 87  ? -5.231  -8.168  39.75   1    126.55 ? 76  GLN C OE1 1 -0.048 -0.075 0.099  
ATOM   6754  N  NE2 . GLN C 1 87  ? -4.371  -10.007 40.729  1    135.62 ? 76  GLN C NE2 1 -0.04  -0.092 0.102  
ATOM   6755  N  N   . GLU C 1 88  ? -7.8    -5.926  41.279  1    121.02 ? 77  GLU C N   1 -0.071 -0.054 0.103  
ATOM   6756  C  CA  . GLU C 1 88  ? -6.907  -4.901  41.815  1    126.17 ? 77  GLU C CA  1 -0.063 -0.045 0.104  
ATOM   6757  C  C   . GLU C 1 88  ? -7.348  -4.416  43.19   1    129.06 ? 77  GLU C C   1 -0.067 -0.04  0.108  
ATOM   6758  O  O   . GLU C 1 88  ? -6.504  -4.039  44.014  1    129.72 ? 77  GLU C O   1 -0.06  -0.037 0.11   
ATOM   6759  C  CB  . GLU C 1 88  ? -6.823  -3.714  40.855  1    128.42 ? 77  GLU C CB  1 -0.063 -0.034 0.102  
ATOM   6760  C  CG  . GLU C 1 88  ? -8.08   -2.821  40.817  1    131.17 ? 77  GLU C CG  1 -0.074 -0.026 0.102  
ATOM   6761  C  CD  . GLU C 1 88  ? -8.151  -1.817  41.978  1    137.64 ? 77  GLU C CD  1 -0.075 -0.017 0.105  
ATOM   6762  O  OE1 . GLU C 1 88  ? -7.072  -1.421  42.488  1    139.1  ? 77  GLU C OE1 1 -0.065 -0.013 0.106  
ATOM   6763  O  OE2 . GLU C 1 88  ? -9.281  -1.453  42.395  1    135.09 ? 77  GLU C OE2 1 -0.085 -0.013 0.106  
ATOM   6764  N  N   . THR C 1 89  ? -8.658  -4.387  43.446  1    127    ? 78  THR C N   1 -0.079 -0.04  0.108  
ATOM   6765  C  CA  . THR C 1 89  ? -9.184  -3.719  44.631  1    128.43 ? 78  THR C CA  1 -0.084 -0.034 0.111  
ATOM   6766  C  C   . THR C 1 89  ? -8.671  -4.373  45.904  1    126.2  ? 78  THR C C   1 -0.079 -0.04  0.115  
ATOM   6767  O  O   . THR C 1 89  ? -9.015  -5.519  46.21   1    125.98 ? 78  THR C O   1 -0.083 -0.051 0.115  
ATOM   6768  C  CB  . THR C 1 89  ? -10.712 -3.713  44.61   1    126.14 ? 78  THR C CB  1 -0.098 -0.034 0.111  
ATOM   6769  O  OG1 . THR C 1 89  ? -11.162 -3.276  43.314  1    121.23 ? 78  THR C OG1 1 -0.102 -0.03  0.108  
ATOM   6770  C  CG2 . THR C 1 89  ? -11.252 -2.79   45.716  1    114.83 ? 78  THR C CG2 1 -0.103 -0.026 0.114  
ATOM   6771  N  N   . ARG C 1 90  ? -7.813  -3.657  46.622  1    127.83 ? 79  ARG C N   1 -0.072 -0.034 0.116  
ATOM   6772  C  CA  . ARG C 1 90  ? -7.342  -4.136  47.91   1    131.93 ? 79  ARG C CA  1 -0.067 -0.038 0.12   
ATOM   6773  C  C   . ARG C 1 90  ? -8.503  -4.165  48.898  1    133.03 ? 79  ARG C C   1 -0.078 -0.038 0.122  
ATOM   6774  O  O   . ARG C 1 90  ? -9.453  -3.38   48.799  1    134.67 ? 79  ARG C O   1 -0.087 -0.031 0.122  
ATOM   6775  C  CB  . ARG C 1 90  ? -6.214  -3.238  48.418  1    130.96 ? 79  ARG C CB  1 -0.057 -0.03  0.121  
ATOM   6776  C  CG  . ARG C 1 90  ? -6.646  -1.797  48.7    1    136.89 ? 79  ARG C CG  1 -0.061 -0.016 0.122  
ATOM   6777  C  CD  . ARG C 1 90  ? -7.332  -1.675  50.077  1    146.6  ? 79  ARG C CD  1 -0.067 -0.015 0.125  
ATOM   6778  N  NE  . ARG C 1 90  ? -7.975  -0.383  50.282  1    154.01 ? 79  ARG C NE  1 -0.073 -0.004 0.126  
ATOM   6779  C  CZ  . ARG C 1 90  ? -7.534  0.543   51.123  1    157.58 ? 79  ARG C CZ  1 -0.069 0.005  0.128  
ATOM   6780  N  NH1 . ARG C 1 90  ? -6.477  0.328   51.893  1    156.56 ? 79  ARG C NH1 1 -0.059 0.003  0.13   
ATOM   6781  N  NH2 . ARG C 1 90  ? -8.169  1.709   51.196  1    157.95 ? 79  ARG C NH2 1 -0.075 0.016  0.128  
ATOM   6782  N  N   . LEU C 1 91  ? -8.425  -5.064  49.868  1    125.82 ? 80  LEU C N   1 -0.077 -0.046 0.125  
ATOM   6783  C  CA  . LEU C 1 91  ? -9.425  -5.076  50.92   1    120.56 ? 80  LEU C CA  1 -0.086 -0.047 0.127  
ATOM   6784  C  C   . LEU C 1 91  ? -8.697  -5.167  52.249  1    121.37 ? 80  LEU C C   1 -0.08  -0.047 0.13   
ATOM   6785  O  O   . LEU C 1 91  ? -7.6    -5.733  52.315  1    122.91 ? 80  LEU C O   1 -0.07  -0.053 0.131  
ATOM   6786  C  CB  . LEU C 1 91  ? -10.42  -6.24   50.75   1    118.11 ? 80  LEU C CB  1 -0.095 -0.057 0.127  
ATOM   6787  C  CG  . LEU C 1 91  ? -11.463 -6.177  49.623  1    113.61 ? 80  LEU C CG  1 -0.105 -0.057 0.124  
ATOM   6788  C  CD1 . LEU C 1 91  ? -12.327 -7.413  49.613  1    103    ? 80  LEU C CD1 1 -0.113 -0.068 0.124  
ATOM   6789  C  CD2 . LEU C 1 91  ? -12.336 -4.977  49.833  1    116.26 ? 80  LEU C CD2 1 -0.113 -0.046 0.124  
ATOM   6790  N  N   . PRO C 1 92  ? -9.254  -4.58   53.309  1    124.43 ? 81  PRO C N   1 -0.085 -0.042 0.133  
ATOM   6791  C  CA  . PRO C 1 92  ? -8.594  -4.64   54.623  1    112.2  ? 81  PRO C CA  1 -0.079 -0.043 0.136  
ATOM   6792  C  C   . PRO C 1 92  ? -8.609  -6.047  55.204  1    112.25 ? 81  PRO C C   1 -0.079 -0.055 0.138  
ATOM   6793  O  O   . PRO C 1 92  ? -9.481  -6.864  54.9    1    111.26 ? 81  PRO C O   1 -0.087 -0.063 0.137  
ATOM   6794  C  CB  . PRO C 1 92  ? -9.424  -3.677  55.482  1    113.96 ? 81  PRO C CB  1 -0.086 -0.034 0.139  
ATOM   6795  C  CG  . PRO C 1 92  ? -10.77  -3.623  54.813  1    113.17 ? 81  PRO C CG  1 -0.099 -0.033 0.137  
ATOM   6796  C  CD  . PRO C 1 92  ? -10.478 -3.75   53.334  1    120.1  ? 81  PRO C CD  1 -0.096 -0.034 0.133  
ATOM   6797  N  N   . TYR C 1 93  ? -7.645  -6.296  56.103  1    116.92 ? 82  TYR C N   1 -0.07  -0.058 0.14   
ATOM   6798  C  CA  . TYR C 1 93  ? -7.335  -7.654  56.56   1    114.46 ? 82  TYR C CA  1 -0.067 -0.07  0.141  
ATOM   6799  C  C   . TYR C 1 93  ? -8.559  -8.423  57.042  1    110.83 ? 82  TYR C C   1 -0.078 -0.077 0.142  
ATOM   6800  O  O   . TYR C 1 93  ? -8.575  -9.658  56.987  1    108.28 ? 82  TYR C O   1 -0.079 -0.089 0.142  
ATOM   6801  C  CB  . TYR C 1 93  ? -6.27   -7.628  57.675  1    115.4  ? 82  TYR C CB  1 -0.057 -0.07  0.144  
ATOM   6802  C  CG  . TYR C 1 93  ? -6.576  -6.751  58.89   1    122.09 ? 82  TYR C CG  1 -0.06  -0.062 0.147  
ATOM   6803  C  CD1 . TYR C 1 93  ? -7.746  -6.914  59.632  1    124.94 ? 82  TYR C CD1 1 -0.071 -0.063 0.149  
ATOM   6804  C  CD2 . TYR C 1 93  ? -5.671  -5.782  59.32   1    126.68 ? 82  TYR C CD2 1 -0.052 -0.053 0.148  
ATOM   6805  C  CE1 . TYR C 1 93  ? -8.027  -6.119  60.743  1    127.79 ? 82  TYR C CE1 1 -0.074 -0.056 0.152  
ATOM   6806  C  CE2 . TYR C 1 93  ? -5.942  -4.983  60.438  1    127.91 ? 82  TYR C CE2 1 -0.054 -0.046 0.151  
ATOM   6807  C  CZ  . TYR C 1 93  ? -7.124  -5.161  61.14   1    128.84 ? 82  TYR C CZ  1 -0.065 -0.047 0.153  
ATOM   6808  O  OH  . TYR C 1 93  ? -7.419  -4.388  62.239  1    130.19 ? 82  TYR C OH  1 -0.068 -0.04  0.155  
ATOM   6809  N  N   . TYR C 1 94  ? -9.588  -7.728  57.52   1    109.19 ? 83  TYR C N   1 -0.088 -0.071 0.144  
ATOM   6810  C  CA  . TYR C 1 94  ? -10.704 -8.42   58.145  1    115.06 ? 83  TYR C CA  1 -0.098 -0.077 0.145  
ATOM   6811  C  C   . TYR C 1 94  ? -11.753 -8.883  57.138  1    112.64 ? 83  TYR C C   1 -0.108 -0.081 0.143  
ATOM   6812  O  O   . TYR C 1 94  ? -12.544 -9.777  57.456  1    117.39 ? 83  TYR C O   1 -0.115 -0.09  0.143  
ATOM   6813  C  CB  . TYR C 1 94  ? -11.321 -7.538  59.25   1    114.56 ? 83  TYR C CB  1 -0.104 -0.069 0.148  
ATOM   6814  C  CG  . TYR C 1 94  ? -11.608 -6.106  58.846  1    116.76 ? 83  TYR C CG  1 -0.106 -0.056 0.147  
ATOM   6815  C  CD1 . TYR C 1 94  ? -10.617 -5.112  58.888  1    112.64 ? 83  TYR C CD1 1 -0.097 -0.047 0.147  
ATOM   6816  C  CD2 . TYR C 1 94  ? -12.881 -5.741  58.424  1    118.97 ? 83  TYR C CD2 1 -0.118 -0.053 0.146  
ATOM   6817  C  CE1 . TYR C 1 94  ? -10.898 -3.79   58.519  1    110.65 ? 83  TYR C CE1 1 -0.1   -0.035 0.146  
ATOM   6818  C  CE2 . TYR C 1 94  ? -13.173 -4.437  58.037  1    120.27 ? 83  TYR C CE2 1 -0.121 -0.041 0.145  
ATOM   6819  C  CZ  . TYR C 1 94  ? -12.188 -3.46   58.089  1    117.53 ? 83  TYR C CZ  1 -0.112 -0.032 0.145  
ATOM   6820  O  OH  . TYR C 1 94  ? -12.526 -2.173  57.699  1    111.75 ? 83  TYR C OH  1 -0.115 -0.02  0.144  
ATOM   6821  N  N   . TRP C 1 95  ? -11.774 -8.312  55.931  1    113.2  ? 84  TRP C N   1 -0.108 -0.076 0.14   
ATOM   6822  C  CA  . TRP C 1 95  ? -12.483 -8.958  54.829  1    105.58 ? 84  TRP C CA  1 -0.114 -0.082 0.137  
ATOM   6823  C  C   . TRP C 1 95  ? -11.695 -10.147 54.297  1    106.04 ? 84  TRP C C   1 -0.107 -0.093 0.136  
ATOM   6824  O  O   . TRP C 1 95  ? -12.278 -11.191 53.992  1    109.79 ? 84  TRP C O   1 -0.113 -0.103 0.135  
ATOM   6825  C  CB  . TRP C 1 95  ? -12.755 -7.962  53.707  1    94.49  ? 84  TRP C CB  1 -0.117 -0.073 0.134  
ATOM   6826  C  CG  . TRP C 1 95  ? -13.893 -7.058  53.976  1    93.03  ? 84  TRP C CG  1 -0.127 -0.065 0.135  
ATOM   6827  C  CD1 . TRP C 1 95  ? -13.832 -5.717  54.259  1    99.54  ? 84  TRP C CD1 1 -0.127 -0.052 0.135  
ATOM   6828  C  CD2 . TRP C 1 95  ? -15.278 -7.412  54.004  1    85.87  ? 84  TRP C CD2 1 -0.14  -0.068 0.135  
ATOM   6829  N  NE1 . TRP C 1 95  ? -15.099 -5.217  54.463  1    95.2   ? 84  TRP C NE1 1 -0.138 -0.048 0.136  
ATOM   6830  C  CE2 . TRP C 1 95  ? -16.005 -6.235  54.309  1    89.46  ? 84  TRP C CE2 1 -0.147 -0.057 0.136  
ATOM   6831  C  CE3 . TRP C 1 95  ? -15.974 -8.605  53.817  1    84.4   ? 84  TRP C CE3 1 -0.146 -0.079 0.134  
ATOM   6832  C  CZ2 . TRP C 1 95  ? -17.399 -6.217  54.411  1    86.7   ? 84  TRP C CZ2 1 -0.159 -0.057 0.136  
ATOM   6833  C  CZ3 . TRP C 1 95  ? -17.368 -8.586  53.92   1    85.53  ? 84  TRP C CZ3 1 -0.159 -0.079 0.135  
ATOM   6834  C  CH2 . TRP C 1 95  ? -18.062 -7.397  54.2    1    82.07  ? 84  TRP C CH2 1 -0.166 -0.068 0.135  
ATOM   6835  N  N   . LEU C 1 96  ? -10.375 -10.009 54.178  1    103.87 ? 85  LEU C N   1 -0.095 -0.092 0.135  
ATOM   6836  C  CA  . LEU C 1 96  ? -9.542  -11.142 53.786  1    104.44 ? 85  LEU C CA  1 -0.087 -0.102 0.134  
ATOM   6837  C  C   . LEU C 1 96  ? -9.613  -12.271 54.815  1    111.39 ? 85  LEU C C   1 -0.088 -0.112 0.137  
ATOM   6838  O  O   . LEU C 1 96  ? -9.557  -13.452 54.452  1    110.26 ? 85  LEU C O   1 -0.088 -0.123 0.136  
ATOM   6839  C  CB  . LEU C 1 96  ? -8.094  -10.689 53.598  1    105.99 ? 85  LEU C CB  1 -0.074 -0.098 0.134  
ATOM   6840  C  CG  . LEU C 1 96  ? -7.679  -9.876  52.371  1    111.97 ? 85  LEU C CG  1 -0.07  -0.091 0.131  
ATOM   6841  C  CD1 . LEU C 1 96  ? -8.644  -8.759  52.084  1    113.1  ? 85  LEU C CD1 1 -0.079 -0.08  0.13   
ATOM   6842  C  CD2 . LEU C 1 96  ? -6.288  -9.304  52.56   1    114.69 ? 85  LEU C CD2 1 -0.058 -0.085 0.131  
ATOM   6843  N  N   . ASP C 1 97  ? -9.701  -11.928 56.109  1    114.33 ? 86  ASP C N   1 -0.089 -0.109 0.14   
ATOM   6844  C  CA  . ASP C 1 97  ? -9.952  -12.947 57.127  1    116.37 ? 86  ASP C CA  1 -0.091 -0.119 0.143  
ATOM   6845  C  C   . ASP C 1 97  ? -11.275 -13.659 56.856  1    112.74 ? 86  ASP C C   1 -0.103 -0.125 0.142  
ATOM   6846  O  O   . ASP C 1 97  ? -11.317 -14.89  56.731  1    109.29 ? 86  ASP C O   1 -0.104 -0.136 0.142  
ATOM   6847  C  CB  . ASP C 1 97  ? -9.952  -12.319 58.536  1    114.06 ? 86  ASP C CB  1 -0.091 -0.113 0.146  
ATOM   6848  C  CG  . ASP C 1 97  ? -8.542  -11.998 59.047  1    122.3  ? 86  ASP C CG  1 -0.078 -0.11  0.147  
ATOM   6849  O  OD1 . ASP C 1 97  ? -7.577  -12.217 58.278  1    127.77 ? 86  ASP C OD1 1 -0.069 -0.112 0.146  
ATOM   6850  O  OD2 . ASP C 1 97  ? -8.399  -11.528 60.209  1    119.49 ? 86  ASP C OD2 1 -0.077 -0.106 0.15   
ATOM   6851  N  N   . LEU C 1 98  ? -12.361 -12.885 56.728  1    109.71 ? 87  LEU C N   1 -0.113 -0.118 0.142  
ATOM   6852  C  CA  . LEU C 1 98  ? -13.698 -13.469 56.662  1    100.82 ? 87  LEU C CA  1 -0.126 -0.123 0.141  
ATOM   6853  C  C   . LEU C 1 98  ? -13.819 -14.404 55.482  1    105.22 ? 87  LEU C C   1 -0.127 -0.132 0.139  
ATOM   6854  O  O   . LEU C 1 98  ? -14.31  -15.531 55.618  1    100.68 ? 87  LEU C O   1 -0.131 -0.142 0.139  
ATOM   6855  C  CB  . LEU C 1 98  ? -14.743 -12.367 56.57   1    100.85 ? 87  LEU C CB  1 -0.135 -0.113 0.141  
ATOM   6856  C  CG  . LEU C 1 98  ? -16.175 -12.794 56.281  1    100.12 ? 87  LEU C CG  1 -0.148 -0.117 0.141  
ATOM   6857  C  CD1 . LEU C 1 98  ? -16.609 -13.937 57.162  1    105.88 ? 87  LEU C CD1 1 -0.152 -0.128 0.143  
ATOM   6858  C  CD2 . LEU C 1 98  ? -17.067 -11.6   56.527  1    104.58 ? 87  LEU C CD2 1 -0.156 -0.106 0.141  
ATOM   6859  N  N   . PHE C 1 99  ? -13.395 -13.931 54.304  1    115.61 ? 88  PHE C N   1 -0.123 -0.128 0.136  
ATOM   6860  C  CA  . PHE C 1 99  ? -13.197 -14.771 53.13   1    106.77 ? 88  PHE C CA  1 -0.121 -0.135 0.133  
ATOM   6861  C  C   . PHE C 1 99  ? -12.492 -16.069 53.507  1    111.42 ? 88  PHE C C   1 -0.114 -0.147 0.134  
ATOM   6862  O  O   . PHE C 1 99  ? -13.069 -17.158 53.401  1    113.89 ? 88  PHE C O   1 -0.12  -0.157 0.133  
ATOM   6863  C  CB  . PHE C 1 99  ? -12.377 -14.015 52.082  1    98.82  ? 88  PHE C CB  1 -0.113 -0.128 0.13   
ATOM   6864  C  CG  . PHE C 1 99  ? -13.043 -12.778 51.561  1    98.89  ? 88  PHE C CG  1 -0.12  -0.117 0.129  
ATOM   6865  C  CD1 . PHE C 1 99  ? -14.398 -12.546 51.775  1    94.75  ? 88  PHE C CD1 1 -0.132 -0.115 0.129  
ATOM   6866  C  CD2 . PHE C 1 99  ? -12.312 -11.842 50.837  1    98.31  ? 88  PHE C CD2 1 -0.113 -0.109 0.127  
ATOM   6867  C  CE1 . PHE C 1 99  ? -15.011 -11.394 51.268  1    95.04  ? 88  PHE C CE1 1 -0.138 -0.104 0.128  
ATOM   6868  C  CE2 . PHE C 1 99  ? -12.914 -10.698 50.333  1    96.3   ? 88  PHE C CE2 1 -0.118 -0.098 0.126  
ATOM   6869  C  CZ  . PHE C 1 99  ? -14.265 -10.472 50.547  1    91.14  ? 88  PHE C CZ  1 -0.131 -0.096 0.126  
ATOM   6870  N  N   . ALA C 1 100 ? -11.244 -15.953 53.988  1    107.69 ? 89  ALA C N   1 -0.103 -0.146 0.135  
ATOM   6871  C  CA  . ALA C 1 100 ? -10.426 -17.13  54.26   1    101.35 ? 89  ALA C CA  1 -0.096 -0.157 0.135  
ATOM   6872  C  C   . ALA C 1 100 ? -11.137 -18.125 55.157  1    108.14 ? 89  ALA C C   1 -0.102 -0.166 0.138  
ATOM   6873  O  O   . ALA C 1 100 ? -10.85  -19.323 55.085  1    106.07 ? 89  ALA C O   1 -0.099 -0.177 0.138  
ATOM   6874  C  CB  . ALA C 1 100 ? -9.099  -16.718 54.886  1    99     ? 89  ALA C CB  1 -0.083 -0.153 0.137  
ATOM   6875  N  N   . ALA C 1 101 ? -12.082 -17.651 55.987  1    109.35 ? 90  ALA C N   1 -0.111 -0.162 0.14   
ATOM   6876  C  CA  . ALA C 1 101 ? -12.873 -18.531 56.852  1    110.34 ? 90  ALA C CA  1 -0.118 -0.17  0.142  
ATOM   6877  C  C   . ALA C 1 101 ? -14.087 -19.124 56.135  1    112.65 ? 90  ALA C C   1 -0.129 -0.175 0.14   
ATOM   6878  O  O   . ALA C 1 101 ? -14.543 -20.212 56.508  1    114.67 ? 90  ALA C O   1 -0.133 -0.185 0.141  
ATOM   6879  C  CB  . ALA C 1 101 ? -13.33  -17.777 58.105  1    108.78 ? 90  ALA C CB  1 -0.122 -0.163 0.145  
ATOM   6880  N  N   . ILE C 1 102 ? -14.645 -18.429 55.139  1    110.97 ? 91  ILE C N   1 -0.134 -0.169 0.138  
ATOM   6881  C  CA  . ILE C 1 102 ? -15.622 -19.071 54.263  1    114.23 ? 91  ILE C CA  1 -0.143 -0.175 0.135  
ATOM   6882  C  C   . ILE C 1 102 ? -14.951 -20.081 53.339  1    108.04 ? 91  ILE C C   1 -0.137 -0.184 0.133  
ATOM   6883  O  O   . ILE C 1 102 ? -15.624 -20.945 52.772  1    106.4  ? 91  ILE C O   1 -0.143 -0.192 0.132  
ATOM   6884  C  CB  . ILE C 1 102 ? -16.383 -18.02  53.433  1    113.37 ? 91  ILE C CB  1 -0.15  -0.165 0.133  
ATOM   6885  C  CG1 . ILE C 1 102 ? -16.741 -16.816 54.307  1    110.57 ? 91  ILE C CG1 1 -0.153 -0.154 0.136  
ATOM   6886  C  CG2 . ILE C 1 102 ? -17.647 -18.63  52.84   1    109.67 ? 91  ILE C CG2 1 -0.162 -0.171 0.132  
ATOM   6887  C  CD1 . ILE C 1 102 ? -17.389 -15.691 53.536  1    109.11 ? 91  ILE C CD1 1 -0.159 -0.144 0.134  
ATOM   6888  N  N   . ASP C 1 103 ? -13.627 -20.002 53.191  1    107.26 ? 92  ASP C N   1 -0.125 -0.183 0.133  
ATOM   6889  C  CA  . ASP C 1 103 ? -12.918 -20.91  52.297  1    107.99 ? 92  ASP C CA  1 -0.118 -0.192 0.131  
ATOM   6890  C  C   . ASP C 1 103 ? -12.909 -22.346 52.833  1    111.63 ? 92  ASP C C   1 -0.118 -0.205 0.132  
ATOM   6891  O  O   . ASP C 1 103 ? -13.338 -23.272 52.135  1    116.68 ? 92  ASP C O   1 -0.122 -0.213 0.13   
ATOM   6892  C  CB  . ASP C 1 103 ? -11.495 -20.389 52.046  1    107.37 ? 92  ASP C CB  1 -0.105 -0.187 0.13   
ATOM   6893  C  CG  . ASP C 1 103 ? -11.445 -19.164 51.083  1    120.24 ? 92  ASP C CG  1 -0.105 -0.176 0.128  
ATOM   6894  O  OD1 . ASP C 1 103 ? -10.396 -18.984 50.411  1    120.01 ? 92  ASP C OD1 1 -0.095 -0.174 0.126  
ATOM   6895  O  OD2 . ASP C 1 103 ? -12.44  -18.389 50.982  1    123.88 ? 92  ASP C OD2 1 -0.114 -0.169 0.127  
ATOM   6896  N  N   . GLU C 1 104 ? -12.44  -22.558 54.071  1    120.78 ? 93  GLU C N   1 -0.114 -0.207 0.135  
ATOM   6897  C  CA  . GLU C 1 104 ? -12.256 -23.907 54.601  1    116.89 ? 93  GLU C CA  1 -0.112 -0.219 0.136  
ATOM   6898  C  C   . GLU C 1 104 ? -13.491 -24.447 55.324  1    111.67 ? 93  GLU C C   1 -0.124 -0.224 0.138  
ATOM   6899  O  O   . GLU C 1 104 ? -13.382 -25.435 56.062  1    108.27 ? 93  GLU C O   1 -0.123 -0.233 0.14   
ATOM   6900  C  CB  . GLU C 1 104 ? -11.023 -23.968 55.52   1    106.5  ? 93  GLU C CB  1 -0.101 -0.22  0.139  
ATOM   6901  C  CG  . GLU C 1 104 ? -11.149 -23.336 56.891  1    117.78 ? 93  GLU C CG  1 -0.102 -0.214 0.142  
ATOM   6902  C  CD  . GLU C 1 104 ? -11.283 -21.819 56.849  1    122.37 ? 93  GLU C CD  1 -0.103 -0.2   0.142  
ATOM   6903  O  OE1 . GLU C 1 104 ? -12.085 -21.346 56.011  1    112.96 ? 93  GLU C OE1 1 -0.111 -0.196 0.14   
ATOM   6904  O  OE2 . GLU C 1 104 ? -10.601 -21.113 57.655  1    118.39 ? 93  GLU C OE2 1 -0.097 -0.193 0.144  
ATOM   6905  N  N   . GLY C 1 105 ? -14.666 -23.866 55.085  1    113.99 ? 94  GLY C N   1 -0.134 -0.219 0.138  
ATOM   6906  C  CA  . GLY C 1 105 ? -15.893 -24.443 55.602  1    113.04 ? 94  GLY C CA  1 -0.146 -0.224 0.139  
ATOM   6907  C  C   . GLY C 1 105 ? -16.005 -24.369 57.105  1    116.77 ? 94  GLY C C   1 -0.147 -0.223 0.143  
ATOM   6908  O  O   . GLY C 1 105 ? -16.658 -25.221 57.72   1    120.83 ? 94  GLY C O   1 -0.153 -0.231 0.144  
ATOM   6909  N  N   . ASP C 1 106 ? -15.365 -23.366 57.712  1    115.37 ? 95  ASP C N   1 -0.141 -0.214 0.144  
ATOM   6910  C  CA  . ASP C 1 106 ? -15.456 -23.105 59.146  1    109.19 ? 95  ASP C CA  1 -0.142 -0.212 0.148  
ATOM   6911  C  C   . ASP C 1 106 ? -16.61  -22.137 59.398  1    104.79 ? 95  ASP C C   1 -0.152 -0.203 0.148  
ATOM   6912  O  O   . ASP C 1 106 ? -16.438 -20.922 59.524  1    103.09 ? 95  ASP C O   1 -0.151 -0.192 0.149  
ATOM   6913  C  CB  . ASP C 1 106 ? -14.134 -22.554 59.664  1    114.29 ? 95  ASP C CB  1 -0.13  -0.207 0.149  
ATOM   6914  C  CG  . ASP C 1 106 ? -13.879 -22.912 61.131  1    119.46 ? 95  ASP C CG  1 -0.127 -0.21  0.153  
ATOM   6915  O  OD1 . ASP C 1 106 ? -14.799 -22.749 61.983  1    108.8  ? 95  ASP C OD1 1 -0.136 -0.208 0.155  
ATOM   6916  O  OD2 . ASP C 1 106 ? -12.748 -23.371 61.419  1    122.12 ? 95  ASP C OD2 1 -0.117 -0.214 0.153  
ATOM   6917  N  N   . THR C 1 107 ? -17.814 -22.706 59.482  1    102.12 ? 96  THR C N   1 -0.163 -0.208 0.149  
ATOM   6918  C  CA  . THR C 1 107 ? -19.018 -21.897 59.676  1    108.37 ? 96  THR C CA  1 -0.174 -0.201 0.149  
ATOM   6919  C  C   . THR C 1 107 ? -18.955 -20.997 60.914  1    114.64 ? 96  THR C C   1 -0.174 -0.192 0.152  
ATOM   6920  O  O   . THR C 1 107 ? -19.107 -19.768 60.77   1    111.49 ? 96  THR C O   1 -0.175 -0.181 0.152  
ATOM   6921  C  CB  . THR C 1 107 ? -20.235 -22.827 59.694  1    108.41 ? 96  THR C CB  1 -0.185 -0.209 0.149  
ATOM   6922  O  OG1 . THR C 1 107 ? -20.009 -23.927 58.794  1    98.64  ? 96  THR C OG1 1 -0.183 -0.219 0.147  
ATOM   6923  C  CG2 . THR C 1 107 ? -21.515 -22.072 59.319  1    104.69 ? 96  THR C CG2 1 -0.197 -0.202 0.148  
ATOM   6924  N  N   . PRO C 1 108 ? -18.73  -21.512 62.139  1    116.04 ? 97  PRO C N   1 -0.172 -0.197 0.155  
ATOM   6925  C  CA  . PRO C 1 108 ? -18.722 -20.598 63.298  1    108.54 ? 97  PRO C CA  1 -0.172 -0.189 0.158  
ATOM   6926  C  C   . PRO C 1 108 ? -17.577 -19.6   63.277  1    107.82 ? 97  PRO C C   1 -0.161 -0.18  0.158  
ATOM   6927  O  O   . PRO C 1 108 ? -17.77  -18.45  63.693  1    110.7  ? 97  PRO C O   1 -0.163 -0.169 0.159  
ATOM   6928  C  CB  . PRO C 1 108 ? -18.624 -21.556 64.485  1    106.85 ? 97  PRO C CB  1 -0.171 -0.198 0.161  
ATOM   6929  C  CG  . PRO C 1 108 ? -17.856 -22.7   63.945  1    106.78 ? 97  PRO C CG  1 -0.164 -0.208 0.16   
ATOM   6930  C  CD  . PRO C 1 108 ? -18.383 -22.886 62.556  1    110.05 ? 97  PRO C CD  1 -0.168 -0.21  0.156  
ATOM   6931  N  N   . LYS C 1 109 ? -16.388 -19.998 62.803  1    103.4  ? 98  LYS C N   1 -0.15  -0.183 0.157  
ATOM   6932  C  CA  . LYS C 1 109 ? -15.276 -19.053 62.726  1    99.95  ? 98  LYS C CA  1 -0.14  -0.175 0.157  
ATOM   6933  C  C   . LYS C 1 109 ? -15.606 -17.883 61.811  1    105.09 ? 98  LYS C C   1 -0.143 -0.164 0.154  
ATOM   6934  O  O   . LYS C 1 109 ? -15.311 -16.724 62.133  1    102.49 ? 98  LYS C O   1 -0.14  -0.153 0.155  
ATOM   6935  C  CB  . LYS C 1 109 ? -14.018 -19.761 62.245  1    92.61  ? 98  LYS C CB  1 -0.128 -0.181 0.155  
ATOM   6936  C  CG  . LYS C 1 109 ? -12.833 -18.859 61.986  1    90.82  ? 98  LYS C CG  1 -0.118 -0.173 0.155  
ATOM   6937  C  CD  . LYS C 1 109 ? -11.607 -19.727 61.796  1    90.59  ? 98  LYS C CD  1 -0.106 -0.181 0.154  
ATOM   6938  C  CE  . LYS C 1 109 ? -10.52  -19.034 61.028  1    92.15  ? 98  LYS C CE  1 -0.096 -0.174 0.152  
ATOM   6939  N  NZ  . LYS C 1 109 ? -9.616  -18.18  61.826  1    90.68  ? 98  LYS C NZ  1 -0.088 -0.167 0.154  
ATOM   6940  N  N   . ALA C 1 110 ? -16.217 -18.167 60.659  1    110.42 ? 99  ALA C N   1 -0.149 -0.166 0.151  
ATOM   6941  C  CA  . ALA C 1 110 ? -16.58  -17.088 59.75   1    109.38 ? 99  ALA C CA  1 -0.152 -0.157 0.149  
ATOM   6942  C  C   . ALA C 1 110 ? -17.769 -16.309 60.29   1    109.4  ? 99  ALA C C   1 -0.163 -0.149 0.151  
ATOM   6943  O  O   . ALA C 1 110 ? -17.839 -15.079 60.151  1    112.39 ? 99  ALA C O   1 -0.163 -0.138 0.15   
ATOM   6944  C  CB  . ALA C 1 110 ? -16.882 -17.656 58.364  1    112.79 ? 99  ALA C CB  1 -0.155 -0.162 0.146  
ATOM   6945  N  N   . HIS C 1 111 ? -18.719 -17.013 60.898  1    103.33 ? 100 HIS C N   1 -0.172 -0.156 0.152  
ATOM   6946  C  CA  . HIS C 1 111 ? -19.806 -16.344 61.591  1    109.57 ? 100 HIS C CA  1 -0.182 -0.15  0.154  
ATOM   6947  C  C   . HIS C 1 111 ? -19.26  -15.367 62.622  1    111.46 ? 100 HIS C C   1 -0.177 -0.141 0.156  
ATOM   6948  O  O   . HIS C 1 111 ? -19.733 -14.228 62.736  1    109.86 ? 100 HIS C O   1 -0.181 -0.13  0.157  
ATOM   6949  C  CB  . HIS C 1 111 ? -20.684 -17.408 62.239  1    114.83 ? 100 HIS C CB  1 -0.19  -0.16  0.155  
ATOM   6950  C  CG  . HIS C 1 111 ? -21.779 -16.869 63.1    1    113.9  ? 100 HIS C CG  1 -0.2   -0.155 0.158  
ATOM   6951  N  ND1 . HIS C 1 111 ? -22.394 -17.639 64.062  1    114.46 ? 100 HIS C ND1 1 -0.205 -0.162 0.16   
ATOM   6952  C  CD2 . HIS C 1 111 ? -22.388 -15.66  63.132  1    111.09 ? 100 HIS C CD2 1 -0.205 -0.144 0.158  
ATOM   6953  C  CE1 . HIS C 1 111 ? -23.325 -16.921 64.666  1    120.36 ? 100 HIS C CE1 1 -0.214 -0.155 0.161  
ATOM   6954  N  NE2 . HIS C 1 111 ? -23.344 -15.717 64.12   1    119.04 ? 100 HIS C NE2 1 -0.214 -0.144 0.16   
ATOM   6955  N  N   . ALA C 1 112 ? -18.234 -15.783 63.355  1    109.72 ? 101 ALA C N   1 -0.167 -0.145 0.158  
ATOM   6956  C  CA  . ALA C 1 112 ? -17.636 -14.961 64.404  1    110.04 ? 101 ALA C CA  1 -0.162 -0.137 0.161  
ATOM   6957  C  C   . ALA C 1 112 ? -16.46  -14.157 63.876  1    108.32 ? 101 ALA C C   1 -0.151 -0.13  0.159  
ATOM   6958  O  O   . ALA C 1 112 ? -15.371 -14.165 64.437  1    116.73 ? 101 ALA C O   1 -0.141 -0.13  0.161  
ATOM   6959  C  CB  . ALA C 1 112 ? -17.21  -15.844 65.571  1    114.19 ? 101 ALA C CB  1 -0.158 -0.145 0.164  
ATOM   6960  N  N   . LEU C 1 113 ? -16.689 -13.453 62.78   1    108.66 ? 102 LEU C N   1 -0.153 -0.123 0.157  
ATOM   6961  C  CA  . LEU C 1 113 ? -15.66  -12.724 62.043  1    107.15 ? 102 LEU C CA  1 -0.144 -0.117 0.155  
ATOM   6962  C  C   . LEU C 1 113 ? -16.434 -11.767 61.16   1    106.65 ? 102 LEU C C   1 -0.151 -0.108 0.153  
ATOM   6963  O  O   . LEU C 1 113 ? -16.039 -10.615 60.939  1    103.47 ? 102 LEU C O   1 -0.147 -0.097 0.152  
ATOM   6964  C  CB  . LEU C 1 113 ? -14.782 -13.66  61.211  1    97.96  ? 102 LEU C CB  1 -0.135 -0.125 0.153  
ATOM   6965  C  CG  . LEU C 1 113 ? -13.461 -14.135 61.793  1    98.58  ? 102 LEU C CG  1 -0.123 -0.13  0.154  
ATOM   6966  C  CD1 . LEU C 1 113 ? -12.69  -14.986 60.782  1    103.22 ? 102 LEU C CD1 1 -0.116 -0.137 0.152  
ATOM   6967  C  CD2 . LEU C 1 113 ? -12.649 -12.931 62.214  1    103.27 ? 102 LEU C CD2 1 -0.116 -0.119 0.155  
ATOM   6968  N  N   . PHE C 1 114 ? -17.555 -12.272 60.644  1    104.23 ? 103 PHE C N   1 -0.161 -0.112 0.151  
ATOM   6969  C  CA  . PHE C 1 114 ? -18.64  -11.392 60.25   1    107.47 ? 103 PHE C CA  1 -0.171 -0.104 0.15   
ATOM   6970  C  C   . PHE C 1 114 ? -18.95  -10.411 61.366  1    106.23 ? 103 PHE C C   1 -0.174 -0.095 0.153  
ATOM   6971  O  O   . PHE C 1 114 ? -18.978 -9.197  61.145  1    103.17 ? 103 PHE C O   1 -0.174 -0.084 0.153  
ATOM   6972  C  CB  . PHE C 1 114 ? -19.875 -12.226 59.909  1    109.16 ? 103 PHE C CB  1 -0.182 -0.112 0.15   
ATOM   6973  C  CG  . PHE C 1 114 ? -21.047 -11.415 59.439  1    113.7  ? 103 PHE C CG  1 -0.193 -0.105 0.148  
ATOM   6974  C  CD1 . PHE C 1 114 ? -22.334 -11.93  59.553  1    114.46 ? 103 PHE C CD1 1 -0.205 -0.109 0.149  
ATOM   6975  C  CD2 . PHE C 1 114 ? -20.867 -10.153 58.855  1    112.84 ? 103 PHE C CD2 1 -0.191 -0.093 0.147  
ATOM   6976  C  CE1 . PHE C 1 114 ? -23.442 -11.206 59.114  1    119.86 ? 103 PHE C CE1 1 -0.215 -0.103 0.148  
ATOM   6977  C  CE2 . PHE C 1 114 ? -21.959 -9.41   58.42   1    118.77 ? 103 PHE C CE2 1 -0.201 -0.086 0.146  
ATOM   6978  C  CZ  . PHE C 1 114 ? -23.256 -9.938  58.549  1    126.3  ? 103 PHE C CZ  1 -0.213 -0.091 0.146  
ATOM   6979  N  N   . HIS C 1 115 ? -19.163 -10.922 62.588  1    113.94 ? 104 HIS C N   1 -0.176 -0.1   0.156  
ATOM   6980  C  CA  . HIS C 1 115 ? -19.532 -10.047 63.694  1    108.96 ? 104 HIS C CA  1 -0.179 -0.092 0.159  
ATOM   6981  C  C   . HIS C 1 115 ? -18.344 -9.292  64.271  1    105.12 ? 104 HIS C C   1 -0.168 -0.085 0.16   
ATOM   6982  O  O   . HIS C 1 115 ? -18.559 -8.302  64.979  1    106.26 ? 104 HIS C O   1 -0.17  -0.076 0.162  
ATOM   6983  C  CB  . HIS C 1 115 ? -20.269 -10.838 64.775  1    105.74 ? 104 HIS C CB  1 -0.186 -0.099 0.162  
ATOM   6984  C  CG  . HIS C 1 115 ? -21.642 -11.271 64.353  1    113.72 ? 104 HIS C CG  1 -0.198 -0.103 0.161  
ATOM   6985  N  ND1 . HIS C 1 115 ? -21.899 -12.521 63.827  1    116.5  ? 104 HIS C ND1 1 -0.201 -0.115 0.159  
ATOM   6986  C  CD2 . HIS C 1 115 ? -22.828 -10.612 64.343  1    112.92 ? 104 HIS C CD2 1 -0.209 -0.097 0.161  
ATOM   6987  C  CE1 . HIS C 1 115 ? -23.182 -12.619 63.528  1    111.37 ? 104 HIS C CE1 1 -0.212 -0.116 0.159  
ATOM   6988  N  NE2 . HIS C 1 115 ? -23.77  -11.476 63.833  1    112.48 ? 104 HIS C NE2 1 -0.218 -0.105 0.159  
ATOM   6989  N  N   . LEU C 1 116 ? -17.109 -9.702  63.955  1    102.61 ? 105 LEU C N   1 -0.157 -0.089 0.16   
ATOM   6990  C  CA  . LEU C 1 116 ? -15.922 -8.872  64.168  1    105.7  ? 105 LEU C CA  1 -0.146 -0.081 0.16   
ATOM   6991  C  C   . LEU C 1 116 ? -15.755 -7.744  63.134  1    109.07 ? 105 LEU C C   1 -0.144 -0.071 0.158  
ATOM   6992  O  O   . LEU C 1 116 ? -14.695 -7.105  63.123  1    110.24 ? 105 LEU C O   1 -0.135 -0.065 0.158  
ATOM   6993  C  CB  . LEU C 1 116 ? -14.649 -9.716  64.121  1    105.61 ? 105 LEU C CB  1 -0.134 -0.089 0.16   
ATOM   6994  C  CG  . LEU C 1 116 ? -14.212 -10.69  65.201  1    102.8  ? 105 LEU C CG  1 -0.13  -0.098 0.163  
ATOM   6995  C  CD1 . LEU C 1 116 ? -12.673 -10.733 65.206  1    87.25  ? 105 LEU C CD1 1 -0.116 -0.098 0.163  
ATOM   6996  C  CD2 . LEU C 1 116 ? -14.806 -10.326 66.559  1    105.92 ? 105 LEU C CD2 1 -0.136 -0.095 0.166  
ATOM   6997  N  N   . LEU C 1 117 ? -16.739 -7.481  62.244  1    104.07 ? 106 LEU C N   1 -0.153 -0.069 0.155  
ATOM   6998  C  CA  . LEU C 1 117 ? -16.389 -6.493  61.222  1    106.26 ? 106 LEU C CA  1 -0.15  -0.06  0.153  
ATOM   6999  C  C   . LEU C 1 117 ? -16.747 -5.089  61.685  1    101.08 ? 106 LEU C C   1 -0.153 -0.047 0.154  
ATOM   7000  O  O   . LEU C 1 117 ? -17.899 -4.85   62.078  1    95.9   ? 106 LEU C O   1 -0.164 -0.044 0.155  
ATOM   7001  C  CB  . LEU C 1 117 ? -17.107 -6.767  59.91   1    109.89 ? 106 LEU C CB  1 -0.157 -0.062 0.15   
ATOM   7002  C  CG  . LEU C 1 117 ? -16.886 -8.058  59.128  1    105.58 ? 106 LEU C CG  1 -0.155 -0.074 0.148  
ATOM   7003  C  CD1 . LEU C 1 117 ? -17.896 -8.111  57.994  1    95.85  ? 106 LEU C CD1 1 -0.164 -0.074 0.145  
ATOM   7004  C  CD2 . LEU C 1 117 ? -15.456 -8.189  58.607  1    102.22 ? 106 LEU C CD2 1 -0.142 -0.075 0.146  
ATOM   7005  N  N   . PRO C 1 118 ? -15.793 -4.138  61.596  1    103.83 ? 107 PRO C N   1 -0.145 -0.038 0.154  
ATOM   7006  C  CA  . PRO C 1 118 ? -16.067 -2.739  61.98   1    106.25 ? 107 PRO C CA  1 -0.147 -0.025 0.155  
ATOM   7007  C  C   . PRO C 1 118 ? -17.447 -2.221  61.59   1    107.8  ? 107 PRO C C   1 -0.16  -0.02  0.154  
ATOM   7008  O  O   . PRO C 1 118 ? -17.887 -2.401  60.456  1    114.6  ? 107 PRO C O   1 -0.164 -0.022 0.151  
ATOM   7009  C  CB  . PRO C 1 118 ? -14.958 -1.965  61.25   1    106.55 ? 107 PRO C CB  1 -0.137 -0.018 0.153  
ATOM   7010  C  CG  . PRO C 1 118 ? -13.779 -2.951  61.195  1    99.63  ? 107 PRO C CG  1 -0.126 -0.027 0.153  
ATOM   7011  C  CD  . PRO C 1 118 ? -14.376 -4.355  61.229  1    103.51 ? 107 PRO C CD  1 -0.132 -0.04  0.153  
ATOM   7012  N  N   . GLN C 1 119 ? -18.141 -1.599  62.544  1    117.75 ? 108 GLN C N   1 -0.166 -0.015 0.156  
ATOM   7013  C  CA  . GLN C 1 119 ? -19.412 -0.939  62.27   1    115.65 ? 108 GLN C CA  1 -0.178 -0.009 0.155  
ATOM   7014  C  C   . GLN C 1 119 ? -19.279 0.137   61.199  1    127.31 ? 108 GLN C C   1 -0.177 0.001  0.153  
ATOM   7015  O  O   . GLN C 1 119 ? -20.268 0.452   60.525  1    122.95 ? 108 GLN C O   1 -0.186 0.004  0.151  
ATOM   7016  C  CB  . GLN C 1 119 ? -19.961 -0.326  63.565  1    126.86 ? 108 GLN C CB  1 -0.183 -0.003 0.159  
ATOM   7017  C  CG  . GLN C 1 119 ? -18.879 0.341   64.451  1    131.33 ? 108 GLN C CG  1 -0.173 0.003  0.161  
ATOM   7018  C  CD  . GLN C 1 119 ? -19.405 0.827   65.808  1    132.63 ? 108 GLN C CD  1 -0.178 0.008  0.164  
ATOM   7019  O  OE1 . GLN C 1 119 ? -19.65  2.026   66.005  1    122.58 ? 108 GLN C OE1 1 -0.18  0.019  0.165  
ATOM   7020  N  NE2 . GLN C 1 119 ? -19.567 -0.103  66.753  1    133.2  ? 108 GLN C NE2 1 -0.179 -0.001 0.167  
ATOM   7021  N  N   . ASP C 1 120 ? -18.082 0.705   61.016  1    129.97 ? 109 ASP C N   1 -0.166 0.006  0.152  
ATOM   7022  C  CA  . ASP C 1 120 ? -17.908 1.848   60.129  1    127.32 ? 109 ASP C CA  1 -0.164 0.017  0.15   
ATOM   7023  C  C   . ASP C 1 120 ? -17.367 1.48    58.753  1    121.94 ? 109 ASP C C   1 -0.159 0.014  0.147  
ATOM   7024  O  O   . ASP C 1 120 ? -17.278 2.366   57.896  1    123.61 ? 109 ASP C O   1 -0.158 0.022  0.145  
ATOM   7025  C  CB  . ASP C 1 120 ? -17.005 2.925   60.785  1    136.93 ? 109 ASP C CB  1 -0.156 0.027  0.152  
ATOM   7026  C  CG  . ASP C 1 120 ? -15.508 2.555   60.81   1    143.73 ? 109 ASP C CG  1 -0.142 0.023  0.152  
ATOM   7027  O  OD1 . ASP C 1 120 ? -14.944 2.403   61.925  1    137.17 ? 109 ASP C OD1 1 -0.137 0.022  0.155  
ATOM   7028  O  OD2 . ASP C 1 120 ? -14.907 2.423   59.701  1    152.78 ? 109 ASP C OD2 1 -0.137 0.022  0.149  
ATOM   7029  N  N   . ASP C 1 121 ? -16.997 0.212   58.516  1    121.99 ? 110 ASP C N   1 -0.156 0.002  0.146  
ATOM   7030  C  CA  . ASP C 1 121 ? -16.545 -0.216  57.187  1    118.26 ? 110 ASP C CA  1 -0.152 -0.002 0.143  
ATOM   7031  C  C   . ASP C 1 121 ? -17.596 0.119   56.131  1    110.78 ? 110 ASP C C   1 -0.161 0.001  0.14   
ATOM   7032  O  O   . ASP C 1 121 ? -18.754 -0.31   56.233  1    106.39 ? 110 ASP C O   1 -0.172 -0.003 0.14   
ATOM   7033  C  CB  . ASP C 1 121 ? -16.234 -1.715  57.178  1    112.04 ? 110 ASP C CB  1 -0.149 -0.016 0.143  
ATOM   7034  C  CG  . ASP C 1 121 ? -15.879 -2.241  55.776  1    115.39 ? 110 ASP C CG  1 -0.146 -0.021 0.139  
ATOM   7035  O  OD1 . ASP C 1 121 ? -14.8   -1.872  55.25   1    118.06 ? 110 ASP C OD1 1 -0.136 -0.017 0.138  
ATOM   7036  O  OD2 . ASP C 1 121 ? -16.68  -3.029  55.208  1    106.03 ? 110 ASP C OD2 1 -0.153 -0.028 0.138  
ATOM   7037  N  N   . ILE C 1 122 ? -17.178 0.898   55.122  1    115.59 ? 111 ILE C N   1 -0.157 0.008  0.138  
ATOM   7038  C  CA  . ILE C 1 122 ? -18.103 1.385   54.089  1    117.21 ? 111 ILE C CA  1 -0.166 0.013  0.135  
ATOM   7039  C  C   . ILE C 1 122 ? -18.859 0.224   53.449  1    111.46 ? 111 ILE C C   1 -0.173 0.002  0.133  
ATOM   7040  O  O   . ILE C 1 122 ? -20.098 0.241   53.373  1    106.47 ? 111 ILE C O   1 -0.184 0.002  0.133  
ATOM   7041  C  CB  . ILE C 1 122 ? -17.351 2.202   53.022  1    112.03 ? 111 ILE C CB  1 -0.159 0.02   0.132  
ATOM   7042  C  CG1 . ILE C 1 122 ? -15.994 1.572   52.708  1    114.96 ? 111 ILE C CG1 1 -0.147 0.014  0.132  
ATOM   7043  C  CG2 . ILE C 1 122 ? -17.153 3.626   53.45   1    105.41 ? 111 ILE C CG2 1 -0.157 0.033  0.133  
ATOM   7044  C  CD1 . ILE C 1 122 ? -15.117 2.454   51.811  1    116.38 ? 111 ILE C CD1 1 -0.139 0.022  0.129  
ATOM   7045  N  N   . ILE C 1 123 ? -18.116 -0.792  52.973  1    106.8  ? 112 ILE C N   1 -0.166 -0.007 0.132  
ATOM   7046  C  CA  . ILE C 1 123 ? -18.725 -1.979  52.358  1    106.01 ? 112 ILE C CA  1 -0.172 -0.018 0.131  
ATOM   7047  C  C   . ILE C 1 123 ? -19.88  -2.502  53.215  1    107.41 ? 112 ILE C C   1 -0.182 -0.023 0.133  
ATOM   7048  O  O   . ILE C 1 123 ? -20.979 -2.771  52.702  1    97.34  ? 112 ILE C O   1 -0.192 -0.025 0.132  
ATOM   7049  C  CB  . ILE C 1 123 ? -17.665 -3.076  52.111  1    102.33 ? 112 ILE C CB  1 -0.162 -0.028 0.13   
ATOM   7050  C  CG1 . ILE C 1 123 ? -16.504 -2.574  51.256  1    100.75 ? 112 ILE C CG1 1 -0.151 -0.024 0.128  
ATOM   7051  C  CG2 . ILE C 1 123 ? -18.268 -4.278  51.431  1    96.51  ? 112 ILE C CG2 1 -0.167 -0.039 0.128  
ATOM   7052  C  CD1 . ILE C 1 123 ? -15.372 -2.046  52.092  1    113.16 ? 112 ILE C CD1 1 -0.141 -0.019 0.13   
ATOM   7053  N  N   . LEU C 1 124 ? -19.655 -2.639  54.543  1    109.22 ? 113 LEU C N   1 -0.18  -0.024 0.136  
ATOM   7054  C  CA  . LEU C 1 124 ? -20.683 -3.155  55.453  1    102.54 ? 113 LEU C CA  1 -0.19  -0.029 0.138  
ATOM   7055  C  C   . LEU C 1 124 ? -21.696 -2.087  55.847  1    103.99 ? 113 LEU C C   1 -0.199 -0.019 0.139  
ATOM   7056  O  O   . LEU C 1 124 ? -22.89  -2.387  56.011  1    101.16 ? 113 LEU C O   1 -0.21  -0.022 0.14   
ATOM   7057  C  CB  . LEU C 1 124 ? -20.046 -3.723  56.715  1    102.51 ? 113 LEU C CB  1 -0.184 -0.034 0.142  
ATOM   7058  C  CG  . LEU C 1 124 ? -20.806 -4.832  57.449  1    102.18 ? 113 LEU C CG  1 -0.191 -0.044 0.143  
ATOM   7059  C  CD1 . LEU C 1 124 ? -19.833 -5.462  58.407  1    95.83  ? 113 LEU C CD1 1 -0.182 -0.05  0.146  
ATOM   7060  C  CD2 . LEU C 1 124 ? -22.053 -4.308  58.17   1    97.23  ? 113 LEU C CD2 1 -0.202 -0.039 0.145  
ATOM   7061  N  N   . ARG C 1 125 ? -21.229 -0.859  56.074  1    103.83 ? 114 ARG C N   1 -0.195 -0.008 0.14   
ATOM   7062  C  CA  . ARG C 1 125 ? -22.151 0.24    56.321  1    103.25 ? 114 ARG C CA  1 -0.203 0.002  0.141  
ATOM   7063  C  C   . ARG C 1 125 ? -23.268 0.243   55.285  1    108.5  ? 114 ARG C C   1 -0.213 0.002  0.138  
ATOM   7064  O  O   . ARG C 1 125 ? -24.452 0.19    55.639  1    103.21 ? 114 ARG C O   1 -0.224 0.002  0.139  
ATOM   7065  C  CB  . ARG C 1 125 ? -21.397 1.569   56.322  1    109.47 ? 114 ARG C CB  1 -0.196 0.014  0.141  
ATOM   7066  C  CG  . ARG C 1 125 ? -22.272 2.788   56.609  1    112.17 ? 114 ARG C CG  1 -0.204 0.026  0.141  
ATOM   7067  C  CD  . ARG C 1 125 ? -21.427 3.9     57.209  1    120.83 ? 114 ARG C CD  1 -0.196 0.036  0.143  
ATOM   7068  N  NE  . ARG C 1 125 ? -20.231 4.166   56.412  1    123.41 ? 114 ARG C NE  1 -0.185 0.038  0.141  
ATOM   7069  C  CZ  . ARG C 1 125 ? -20.023 5.278   55.713  1    132.44 ? 114 ARG C CZ  1 -0.183 0.048  0.139  
ATOM   7070  N  NH1 . ARG C 1 125 ? -20.901 6.267   55.695  1    136.13 ? 114 ARG C NH1 1 -0.192 0.057  0.139  
ATOM   7071  N  NH2 . ARG C 1 125 ? -18.898 5.411   55.023  1    130.76 ? 114 ARG C NH2 1 -0.173 0.05   0.137  
ATOM   7072  N  N   . ALA C 1 126 ? -22.902 0.238   53.988  1    112.42 ? 115 ALA C N   1 -0.21  0.002  0.135  
ATOM   7073  C  CA  . ALA C 1 126 ? -23.907 0.272   52.919  1    108.03 ? 115 ALA C CA  1 -0.219 0.002  0.132  
ATOM   7074  C  C   . ALA C 1 126 ? -24.608 -1.075  52.761  1    103.21 ? 115 ALA C C   1 -0.226 -0.01  0.132  
ATOM   7075  O  O   . ALA C 1 126 ? -25.825 -1.126  52.525  1    101.6  ? 115 ALA C O   1 -0.237 -0.01  0.131  
ATOM   7076  C  CB  . ALA C 1 126 ? -23.266 0.699   51.6    1    97.45  ? 115 ALA C CB  1 -0.213 0.006  0.129  
ATOM   7077  N  N   . LEU C 1 127 ? -23.859 -2.17   52.884  1    97.48  ? 116 LEU C N   1 -0.219 -0.02  0.132  
ATOM   7078  C  CA  . LEU C 1 127 ? -24.438 -3.509  52.889  1    103.79 ? 116 LEU C CA  1 -0.224 -0.032 0.132  
ATOM   7079  C  C   . LEU C 1 127 ? -25.608 -3.624  53.875  1    110.4  ? 116 LEU C C   1 -0.235 -0.033 0.135  
ATOM   7080  O  O   . LEU C 1 127 ? -26.767 -3.751  53.459  1    106.85 ? 116 LEU C O   1 -0.245 -0.034 0.133  
ATOM   7081  C  CB  . LEU C 1 127 ? -23.345 -4.527  53.22   1    102.07 ? 116 LEU C CB  1 -0.214 -0.041 0.133  
ATOM   7082  C  CG  . LEU C 1 127 ? -23.389 -5.956  52.694  1    105.78 ? 116 LEU C CG  1 -0.214 -0.055 0.132  
ATOM   7083  C  CD1 . LEU C 1 127 ? -23.919 -6.005  51.263  1    105.97 ? 116 LEU C CD1 1 -0.219 -0.055 0.128  
ATOM   7084  C  CD2 . LEU C 1 127 ? -21.976 -6.515  52.771  1    100.57 ? 116 LEU C CD2 1 -0.201 -0.06  0.132  
ATOM   7085  N  N   . ARG C 1 128 ? -25.316 -3.553  55.184  1    113.81 ? 117 ARG C N   1 -0.232 -0.033 0.138  
ATOM   7086  C  CA  . ARG C 1 128 ? -26.344 -3.668  56.222  1    112.24 ? 117 ARG C CA  1 -0.241 -0.034 0.14   
ATOM   7087  C  C   . ARG C 1 128 ? -27.435 -2.607  56.093  1    110.55 ? 117 ARG C C   1 -0.251 -0.024 0.14   
ATOM   7088  O  O   . ARG C 1 128 ? -28.552 -2.811  56.592  1    104.23 ? 117 ARG C O   1 -0.262 -0.026 0.141  
ATOM   7089  C  CB  . ARG C 1 128 ? -25.688 -3.594  57.609  1    109.35 ? 117 ARG C CB  1 -0.235 -0.033 0.144  
ATOM   7090  C  CG  . ARG C 1 128 ? -25.505 -4.955  58.31   1    107.24 ? 117 ARG C CG  1 -0.234 -0.045 0.146  
ATOM   7091  C  CD  . ARG C 1 128 ? -26.856 -5.548  58.7    1    113.79 ? 117 ARG C CD  1 -0.246 -0.051 0.147  
ATOM   7092  N  NE  . ARG C 1 128 ? -27.699 -4.55   59.355  1    120.12 ? 117 ARG C NE  1 -0.254 -0.042 0.148  
ATOM   7093  C  CZ  . ARG C 1 128 ? -29.025 -4.606  59.434  1    121.07 ? 117 ARG C CZ  1 -0.266 -0.042 0.148  
ATOM   7094  N  NH1 . ARG C 1 128 ? -29.71  -5.615  58.916  1    122.26 ? 117 ARG C NH1 1 -0.272 -0.051 0.147  
ATOM   7095  N  NH2 . ARG C 1 128 ? -29.682 -3.615  60.037  1    109.02 ? 117 ARG C NH2 1 -0.272 -0.033 0.15   
ATOM   7096  N  N   . ALA C 1 129 ? -27.14  -1.491  55.416  1    113.04 ? 118 ALA C N   1 -0.249 -0.014 0.138  
ATOM   7097  C  CA  . ALA C 1 129 ? -28.144 -0.459  55.18   1    113.54 ? 118 ALA C CA  1 -0.258 -0.004 0.138  
ATOM   7098  C  C   . ALA C 1 129 ? -29.237 -0.926  54.227  1    109.69 ? 118 ALA C C   1 -0.268 -0.008 0.135  
ATOM   7099  O  O   . ALA C 1 129 ? -30.374 -0.444  54.312  1    105.57 ? 118 ALA C O   1 -0.278 -0.004 0.136  
ATOM   7100  C  CB  . ALA C 1 129 ? -27.484 0.8     54.624  1    112.18 ? 118 ALA C CB  1 -0.252 0.007  0.136  
ATOM   7101  N  N   . VAL C 1 130 ? -28.922 -1.842  53.31   1    109.95 ? 119 VAL C N   1 -0.265 -0.017 0.133  
ATOM   7102  C  CA  . VAL C 1 130 ? -29.903 -2.309  52.35   1    113.28 ? 119 VAL C CA  1 -0.274 -0.021 0.131  
ATOM   7103  C  C   . VAL C 1 130 ? -30.371 -3.737  52.615  1    110.51 ? 119 VAL C C   1 -0.278 -0.034 0.131  
ATOM   7104  O  O   . VAL C 1 130 ? -31.482 -4.084  52.216  1    109.47 ? 119 VAL C O   1 -0.289 -0.037 0.13   
ATOM   7105  C  CB  . VAL C 1 130 ? -29.403 -2.168  50.896  1    106.6  ? 119 VAL C CB  1 -0.269 -0.02  0.127  
ATOM   7106  C  CG1 . VAL C 1 130 ? -28.965 -0.742  50.621  1    105.29 ? 119 VAL C CG1 1 -0.265 -0.007 0.126  
ATOM   7107  C  CG2 . VAL C 1 130 ? -28.289 -3.152  50.615  1    106.5  ? 119 VAL C CG2 1 -0.259 -0.029 0.126  
ATOM   7108  N  N   . HIS C 1 131 ? -29.566 -4.58   53.261  1    113.04 ? 120 HIS C N   1 -0.271 -0.042 0.133  
ATOM   7109  C  CA  . HIS C 1 131 ? -29.927 -5.98   53.472  1    118.14 ? 120 HIS C CA  1 -0.274 -0.055 0.134  
ATOM   7110  C  C   . HIS C 1 131 ? -29.894 -6.329  54.957  1    117.62 ? 120 HIS C C   1 -0.274 -0.058 0.137  
ATOM   7111  O  O   . HIS C 1 131 ? -29.02  -5.862  55.703  1    115.53 ? 120 HIS C O   1 -0.266 -0.054 0.139  
ATOM   7112  C  CB  . HIS C 1 131 ? -28.99  -6.948  52.709  1    119.27 ? 120 HIS C CB  1 -0.266 -0.064 0.132  
ATOM   7113  C  CG  . HIS C 1 131 ? -29.08  -6.854  51.217  1    114.08 ? 120 HIS C CG  1 -0.266 -0.063 0.128  
ATOM   7114  N  ND1 . HIS C 1 131 ? -30.196 -7.243  50.507  1    113.97 ? 120 HIS C ND1 1 -0.277 -0.066 0.126  
ATOM   7115  C  CD2 . HIS C 1 131 ? -28.169 -6.456  50.296  1    114.1  ? 120 HIS C CD2 1 -0.258 -0.059 0.126  
ATOM   7116  C  CE1 . HIS C 1 131 ? -29.977 -7.063  49.215  1    113.69 ? 120 HIS C CE1 1 -0.275 -0.065 0.123  
ATOM   7117  N  NE2 . HIS C 1 131 ? -28.755 -6.583  49.061  1    111.33 ? 120 HIS C NE2 1 -0.264 -0.06  0.122  
ATOM   7118  N  N   . SER C 1 132 ? -30.839 -7.171  55.38   1    119.36 ? 121 SER C N   1 -0.283 -0.066 0.138  
ATOM   7119  C  CA  . SER C 1 132 ? -30.923 -7.559  56.785  1    120.78 ? 121 SER C CA  1 -0.283 -0.069 0.142  
ATOM   7120  C  C   . SER C 1 132 ? -29.862 -8.6    57.094  1    120.34 ? 121 SER C C   1 -0.274 -0.079 0.143  
ATOM   7121  O  O   . SER C 1 132 ? -29.581 -9.49   56.283  1    117.43 ? 121 SER C O   1 -0.271 -0.087 0.141  
ATOM   7122  C  CB  . SER C 1 132 ? -32.318 -8.093  57.147  1    119.88 ? 121 SER C CB  1 -0.296 -0.074 0.143  
ATOM   7123  O  OG  . SER C 1 132 ? -32.519 -9.449  56.766  1    116.01 ? 121 SER C OG  1 -0.298 -0.087 0.142  
ATOM   7124  N  N   . GLU C 1 133 ? -29.265 -8.472  58.274  1    120.54 ? 122 GLU C N   1 -0.268 -0.078 0.145  
ATOM   7125  C  CA  . GLU C 1 133 ? -28.122 -9.305  58.621  1    115.58 ? 122 GLU C CA  1 -0.258 -0.085 0.146  
ATOM   7126  C  C   . GLU C 1 133 ? -28.499 -10.781 58.669  1    111.67 ? 122 GLU C C   1 -0.261 -0.099 0.146  
ATOM   7127  O  O   . GLU C 1 133 ? -27.637 -11.647 58.487  1    105.13 ? 122 GLU C O   1 -0.253 -0.107 0.146  
ATOM   7128  C  CB  . GLU C 1 133 ? -27.554 -8.823  59.96   1    122.78 ? 122 GLU C CB  1 -0.253 -0.081 0.15   
ATOM   7129  C  CG  . GLU C 1 133 ? -28.183 -9.466  61.241  1    130.42 ? 122 GLU C CG  1 -0.258 -0.087 0.153  
ATOM   7130  C  CD  . GLU C 1 133 ? -29.736 -9.285  61.412  1    138.61 ? 122 GLU C CD  1 -0.273 -0.085 0.153  
ATOM   7131  O  OE1 . GLU C 1 133 ? -30.244 -9.547  62.553  1    128.33 ? 122 GLU C OE1 1 -0.277 -0.087 0.156  
ATOM   7132  O  OE2 . GLU C 1 133 ? -30.444 -8.917  60.426  1    130.54 ? 122 GLU C OE2 1 -0.279 -0.082 0.151  
ATOM   7133  N  N   . ASP C 1 134 ? -29.777 -11.084 58.923  1    113.48 ? 123 ASP C N   1 -0.273 -0.102 0.147  
ATOM   7134  C  CA  . ASP C 1 134 ? -30.267 -12.446 58.763  1    114.81 ? 123 ASP C CA  1 -0.277 -0.114 0.147  
ATOM   7135  C  C   . ASP C 1 134 ? -29.982 -12.946 57.353  1    119.64 ? 123 ASP C C   1 -0.275 -0.119 0.143  
ATOM   7136  O  O   . ASP C 1 134 ? -29.197 -13.882 57.155  1    115.39 ? 123 ASP C O   1 -0.268 -0.127 0.143  
ATOM   7137  C  CB  . ASP C 1 134 ? -31.769 -12.502 59.064  1    120.29 ? 123 ASP C CB  1 -0.291 -0.115 0.147  
ATOM   7138  C  CG  . ASP C 1 134 ? -32.072 -12.665 60.552  1    135.08 ? 123 ASP C CG  1 -0.294 -0.116 0.151  
ATOM   7139  O  OD1 . ASP C 1 134 ? -31.888 -11.692 61.325  1    136.85 ? 123 ASP C OD1 1 -0.292 -0.107 0.153  
ATOM   7140  O  OD2 . ASP C 1 134 ? -32.507 -13.772 60.945  1    136.6  ? 123 ASP C OD2 1 -0.298 -0.126 0.152  
ATOM   7141  N  N   . TYR C 1 135 ? -30.589 -12.295 56.354  1    120.63 ? 124 TYR C N   1 -0.28  -0.113 0.141  
ATOM   7142  C  CA  . TYR C 1 135 ? -30.335 -12.657 54.966  1    113.68 ? 124 TYR C CA  1 -0.278 -0.116 0.137  
ATOM   7143  C  C   . TYR C 1 135 ? -28.834 -12.705 54.672  1    112.3  ? 124 TYR C C   1 -0.264 -0.116 0.137  
ATOM   7144  O  O   . TYR C 1 135 ? -28.34  -13.67  54.08   1    109.95 ? 124 TYR C O   1 -0.26  -0.125 0.135  
ATOM   7145  C  CB  . TYR C 1 135 ? -31.052 -11.683 54.019  1    122.6  ? 124 TYR C CB  1 -0.285 -0.107 0.135  
ATOM   7146  C  CG  . TYR C 1 135 ? -30.824 -12.014 52.543  1    126.66 ? 124 TYR C CG  1 -0.282 -0.11  0.131  
ATOM   7147  C  CD1 . TYR C 1 135 ? -31.646 -12.919 51.874  1    125.72 ? 124 TYR C CD1 1 -0.29  -0.118 0.13   
ATOM   7148  C  CD2 . TYR C 1 135 ? -29.766 -11.443 51.836  1    117.4  ? 124 TYR C CD2 1 -0.273 -0.105 0.129  
ATOM   7149  C  CE1 . TYR C 1 135 ? -31.424 -13.233 50.556  1    122.8  ? 124 TYR C CE1 1 -0.288 -0.121 0.126  
ATOM   7150  C  CE2 . TYR C 1 135 ? -29.534 -11.757 50.53   1    114.04 ? 124 TYR C CE2 1 -0.271 -0.108 0.126  
ATOM   7151  C  CZ  . TYR C 1 135 ? -30.365 -12.646 49.895  1    123.35 ? 124 TYR C CZ  1 -0.278 -0.116 0.125  
ATOM   7152  O  OH  . TYR C 1 135 ? -30.136 -12.938 48.576  1    129.74 ? 124 TYR C OH  1 -0.276 -0.119 0.121  
ATOM   7153  N  N   . LEU C 1 136 ? -28.086 -11.681 55.097  1    106.33 ? 125 LEU C N   1 -0.257 -0.107 0.138  
ATOM   7154  C  CA  . LEU C 1 136 ? -26.635 -11.69  54.888  1    102.77 ? 125 LEU C CA  1 -0.244 -0.107 0.137  
ATOM   7155  C  C   . LEU C 1 136 ? -25.989 -12.97  55.416  1    108.41 ? 125 LEU C C   1 -0.238 -0.119 0.138  
ATOM   7156  O  O   . LEU C 1 136 ? -25.319 -13.687 54.671  1    103.41 ? 125 LEU C O   1 -0.232 -0.125 0.137  
ATOM   7157  C  CB  . LEU C 1 136 ? -25.975 -10.491 55.557  1    110.52 ? 125 LEU C CB  1 -0.238 -0.096 0.139  
ATOM   7158  C  CG  . LEU C 1 136 ? -25.812 -9.138  54.879  1    116.56 ? 125 LEU C CG  1 -0.237 -0.084 0.137  
ATOM   7159  C  CD1 . LEU C 1 136 ? -27.002 -8.255  55.169  1    116.94 ? 125 LEU C CD1 1 -0.247 -0.076 0.138  
ATOM   7160  C  CD2 . LEU C 1 136 ? -24.537 -8.458  55.367  1    111.93 ? 125 LEU C CD2 1 -0.225 -0.078 0.138  
ATOM   7161  N  N   . TYR C 1 137 ? -26.132 -13.252 56.719  1    115.11 ? 126 TYR C N   1 -0.239 -0.121 0.142  
ATOM   7162  C  CA  . TYR C 1 137 ? -25.419 -14.407 57.259  1    108.46 ? 126 TYR C CA  1 -0.233 -0.132 0.143  
ATOM   7163  C  C   . TYR C 1 137 ? -25.906 -15.703 56.614  1    106.39 ? 126 TYR C C   1 -0.237 -0.144 0.141  
ATOM   7164  O  O   . TYR C 1 137 ? -25.105 -16.614 56.352  1    101.15 ? 126 TYR C O   1 -0.23  -0.152 0.141  
ATOM   7165  C  CB  . TYR C 1 137 ? -25.532 -14.483 58.786  1    109.86 ? 126 TYR C CB  1 -0.234 -0.133 0.147  
ATOM   7166  C  CG  . TYR C 1 137 ? -24.926 -15.775 59.323  1    110.12 ? 126 TYR C CG  1 -0.228 -0.145 0.148  
ATOM   7167  C  CD1 . TYR C 1 137 ? -23.568 -16.043 59.148  1    106.24 ? 126 TYR C CD1 1 -0.216 -0.147 0.148  
ATOM   7168  C  CD2 . TYR C 1 137 ? -25.708 -16.747 59.949  1    105.7  ? 126 TYR C CD2 1 -0.236 -0.153 0.15   
ATOM   7169  C  CE1 . TYR C 1 137 ? -22.993 -17.232 59.598  1    99.19  ? 126 TYR C CE1 1 -0.211 -0.158 0.149  
ATOM   7170  C  CE2 . TYR C 1 137 ? -25.136 -17.954 60.409  1    110.52 ? 126 TYR C CE2 1 -0.23  -0.165 0.151  
ATOM   7171  C  CZ  . TYR C 1 137 ? -23.777 -18.186 60.223  1    106.95 ? 126 TYR C CZ  1 -0.218 -0.167 0.15   
ATOM   7172  O  OH  . TYR C 1 137 ? -23.195 -19.365 60.655  1    106.9  ? 126 TYR C OH  1 -0.213 -0.177 0.151  
ATOM   7173  N  N   . GLN C 1 138 ? -27.211 -15.781 56.307  1    108.88 ? 127 GLN C N   1 -0.249 -0.145 0.141  
ATOM   7174  C  CA  . GLN C 1 138 ? -27.761 -16.944 55.606  1    113.38 ? 127 GLN C CA  1 -0.254 -0.155 0.139  
ATOM   7175  C  C   . GLN C 1 138 ? -26.966 -17.257 54.338  1    114.49 ? 127 GLN C C   1 -0.247 -0.158 0.136  
ATOM   7176  O  O   . GLN C 1 138 ? -26.897 -18.418 53.906  1    117.05 ? 127 GLN C O   1 -0.246 -0.169 0.135  
ATOM   7177  C  CB  . GLN C 1 138 ? -29.242 -16.698 55.274  1    111.78 ? 127 GLN C CB  1 -0.268 -0.153 0.138  
ATOM   7178  C  CG  . GLN C 1 138 ? -30.023 -17.908 54.745  1    119.31 ? 127 GLN C CG  1 -0.275 -0.164 0.137  
ATOM   7179  C  CD  . GLN C 1 138 ? -31.509 -17.597 54.476  1    129.06 ? 127 GLN C CD  1 -0.289 -0.161 0.136  
ATOM   7180  O  OE1 . GLN C 1 138 ? -32.083 -16.663 55.06   1    126.6  ? 127 GLN C OE1 1 -0.294 -0.153 0.137  
ATOM   7181  N  NE2 . GLN C 1 138 ? -32.131 -18.383 53.586  1    119.25 ? 127 GLN C NE2 1 -0.294 -0.168 0.134  
ATOM   7182  N  N   . LEU C 1 139 ? -26.323 -16.237 53.762  1    108.13 ? 128 LEU C N   1 -0.241 -0.149 0.134  
ATOM   7183  C  CA  . LEU C 1 139 ? -25.525 -16.391 52.555  1    108.28 ? 128 LEU C CA  1 -0.234 -0.15  0.131  
ATOM   7184  C  C   . LEU C 1 139 ? -24.152 -17.002 52.833  1    111.22 ? 128 LEU C C   1 -0.221 -0.156 0.132  
ATOM   7185  O  O   . LEU C 1 139 ? -23.728 -17.918 52.12   1    110.74 ? 128 LEU C O   1 -0.217 -0.164 0.13   
ATOM   7186  C  CB  . LEU C 1 139 ? -25.369 -15.031 51.893  1    109.82 ? 128 LEU C CB  1 -0.232 -0.138 0.13   
ATOM   7187  C  CG  . LEU C 1 139 ? -25.137 -14.93  50.406  1    109.02 ? 128 LEU C CG  1 -0.23  -0.137 0.126  
ATOM   7188  C  CD1 . LEU C 1 139 ? -25.908 -13.705 49.963  1    102.42 ? 128 LEU C CD1 1 -0.237 -0.126 0.125  
ATOM   7189  C  CD2 . LEU C 1 139 ? -23.641 -14.79  50.192  1    112.64 ? 128 LEU C CD2 1 -0.217 -0.136 0.125  
ATOM   7190  N  N   . ILE C 1 140 ? -23.429 -16.489 53.841  1    113.86 ? 129 ILE C N   1 -0.215 -0.151 0.134  
ATOM   7191  C  CA  . ILE C 1 140 ? -22.1   -17.015 54.163  1    110.14 ? 129 ILE C CA  1 -0.203 -0.156 0.135  
ATOM   7192  C  C   . ILE C 1 140 ? -22.19  -18.503 54.459  1    112.23 ? 129 ILE C C   1 -0.203 -0.17  0.136  
ATOM   7193  O  O   . ILE C 1 140 ? -21.289 -19.286 54.123  1    108.74 ? 129 ILE C O   1 -0.195 -0.177 0.135  
ATOM   7194  C  CB  . ILE C 1 140 ? -21.478 -16.239 55.34   1    105.47 ? 129 ILE C CB  1 -0.197 -0.149 0.138  
ATOM   7195  C  CG1 . ILE C 1 140 ? -21.31  -14.768 54.988  1    105.32 ? 129 ILE C CG1 1 -0.195 -0.135 0.137  
ATOM   7196  C  CG2 . ILE C 1 140 ? -20.122 -16.8   55.709  1    109.73 ? 129 ILE C CG2 1 -0.184 -0.154 0.139  
ATOM   7197  C  CD1 . ILE C 1 140 ? -22.43  -13.846 55.565  1    106.93 ? 129 ILE C CD1 1 -0.206 -0.127 0.139  
ATOM   7198  N  N   . LYS C 1 141 ? -23.292 -18.91  55.086  1    115.39 ? 130 LYS C N   1 -0.213 -0.173 0.138  
ATOM   7199  C  CA  . LYS C 1 141 ? -23.581 -20.322 55.308  1    120.02 ? 130 LYS C CA  1 -0.216 -0.186 0.138  
ATOM   7200  C  C   . LYS C 1 141 ? -23.676 -21.083 53.98   1    112.77 ? 130 LYS C C   1 -0.217 -0.193 0.135  
ATOM   7201  O  O   . LYS C 1 141 ? -22.957 -22.067 53.757  1    109.03 ? 130 LYS C O   1 -0.21  -0.202 0.134  
ATOM   7202  C  CB  . LYS C 1 141 ? -24.88  -20.439 56.119  1    117.45 ? 130 LYS C CB  1 -0.228 -0.187 0.14   
ATOM   7203  C  CG  . LYS C 1 141 ? -24.863 -21.372 57.314  1    113.39 ? 130 LYS C CG  1 -0.228 -0.196 0.143  
ATOM   7204  C  CD  . LYS C 1 141 ? -26.105 -21.122 58.183  1    123.23 ? 130 LYS C CD  1 -0.239 -0.194 0.145  
ATOM   7205  C  CE  . LYS C 1 141 ? -26.463 -22.327 59.075  1    135.82 ? 130 LYS C CE  1 -0.243 -0.205 0.147  
ATOM   7206  N  NZ  . LYS C 1 141 ? -25.473 -22.639 60.163  1    128.74 ? 130 LYS C NZ  1 -0.233 -0.207 0.15   
ATOM   7207  N  N   . TYR C 1 142 ? -24.548 -20.628 53.072  1    111.2  ? 131 TYR C N   1 -0.225 -0.189 0.133  
ATOM   7208  C  CA  . TYR C 1 142 ? -24.752 -21.354 51.818  1    113.5  ? 131 TYR C CA  1 -0.227 -0.196 0.129  
ATOM   7209  C  C   . TYR C 1 142 ? -23.451 -21.527 51.034  1    106.15 ? 131 TYR C C   1 -0.215 -0.197 0.127  
ATOM   7210  O  O   . TYR C 1 142 ? -23.226 -22.582 50.429  1    102    ? 131 TYR C O   1 -0.213 -0.207 0.126  
ATOM   7211  C  CB  . TYR C 1 142 ? -25.806 -20.65  50.971  1    109.51 ? 131 TYR C CB  1 -0.236 -0.189 0.127  
ATOM   7212  C  CG  . TYR C 1 142 ? -27.196 -20.839 51.511  1    114.26 ? 131 TYR C CG  1 -0.249 -0.191 0.129  
ATOM   7213  C  CD1 . TYR C 1 142 ? -27.583 -22.058 52.049  1    118.28 ? 131 TYR C CD1 1 -0.253 -0.202 0.13   
ATOM   7214  C  CD2 . TYR C 1 142 ? -28.12  -19.8   51.499  1    114.84 ? 131 TYR C CD2 1 -0.258 -0.181 0.129  
ATOM   7215  C  CE1 . TYR C 1 142 ? -28.851 -22.244 52.551  1    125.93 ? 131 TYR C CE1 1 -0.264 -0.204 0.131  
ATOM   7216  C  CE2 . TYR C 1 142 ? -29.395 -19.973 52.004  1    119.86 ? 131 TYR C CE2 1 -0.269 -0.183 0.13   
ATOM   7217  C  CZ  . TYR C 1 142 ? -29.756 -21.198 52.529  1    127.94 ? 131 TYR C CZ  1 -0.273 -0.194 0.131  
ATOM   7218  O  OH  . TYR C 1 142 ? -31.027 -21.371 53.035  1    132.35 ? 131 TYR C OH  1 -0.284 -0.196 0.132  
ATOM   7219  N  N   . CYS C 1 143 ? -22.58  -20.51  51.043  1    105.45 ? 132 CYS C N   1 -0.207 -0.188 0.127  
ATOM   7220  C  CA  . CYS C 1 143 ? -21.281 -20.633 50.381  1    105.51 ? 132 CYS C CA  1 -0.195 -0.189 0.126  
ATOM   7221  C  C   . CYS C 1 143 ? -20.444 -21.726 51.028  1    106.51 ? 132 CYS C C   1 -0.187 -0.199 0.127  
ATOM   7222  O  O   . CYS C 1 143 ? -19.823 -22.544 50.339  1    108.58 ? 132 CYS C O   1 -0.182 -0.207 0.126  
ATOM   7223  C  CB  . CYS C 1 143 ? -20.52  -19.305 50.421  1    104.72 ? 132 CYS C CB  1 -0.188 -0.177 0.126  
ATOM   7224  S  SG  . CYS C 1 143 ? -21.408 -17.878 49.761  1    108.85 ? 132 CYS C SG  1 -0.196 -0.164 0.124  
ATOM   7225  N  N   . ILE C 1 144 ? -20.397 -21.735 52.358  1    110.15 ? 133 ILE C N   1 -0.187 -0.199 0.131  
ATOM   7226  C  CA  . ILE C 1 144 ? -19.733 -22.822 53.065  1    109.06 ? 133 ILE C CA  1 -0.181 -0.209 0.132  
ATOM   7227  C  C   . ILE C 1 144 ? -20.379 -24.147 52.687  1    99.84  ? 133 ILE C C   1 -0.187 -0.221 0.132  
ATOM   7228  O  O   . ILE C 1 144 ? -19.701 -25.112 52.313  1    97.27  ? 133 ILE C O   1 -0.181 -0.23  0.131  
ATOM   7229  C  CB  . ILE C 1 144 ? -19.759 -22.558 54.588  1    111.36 ? 133 ILE C CB  1 -0.181 -0.207 0.136  
ATOM   7230  C  CG1 . ILE C 1 144 ? -18.837 -21.37  54.917  1    110.05 ? 133 ILE C CG1 1 -0.173 -0.196 0.137  
ATOM   7231  C  CG2 . ILE C 1 144 ? -19.381 -23.818 55.411  1    100.43 ? 133 ILE C CG2 1 -0.178 -0.218 0.138  
ATOM   7232  C  CD1 . ILE C 1 144 ? -18.947 -20.851 56.323  1    115.46 ? 133 ILE C CD1 1 -0.174 -0.191 0.141  
ATOM   7233  N  N   . GLN C 1 145 ? -21.711 -24.184 52.715  1    94.93  ? 134 GLN C N   1 -0.199 -0.222 0.132  
ATOM   7234  C  CA  . GLN C 1 145 ? -22.413 -25.428 52.444  1    105.05 ? 134 GLN C CA  1 -0.205 -0.233 0.131  
ATOM   7235  C  C   . GLN C 1 145 ? -22.261 -25.845 50.985  1    111.56 ? 134 GLN C C   1 -0.204 -0.237 0.127  
ATOM   7236  O  O   . GLN C 1 145 ? -22.201 -27.047 50.686  1    109.35 ? 134 GLN C O   1 -0.203 -0.248 0.127  
ATOM   7237  C  CB  . GLN C 1 145 ? -23.876 -25.266 52.845  1    108.73 ? 134 GLN C CB  1 -0.219 -0.232 0.132  
ATOM   7238  C  CG  . GLN C 1 145 ? -24.792 -26.336 52.304  1    126.97 ? 134 GLN C CG  1 -0.227 -0.241 0.131  
ATOM   7239  C  CD  . GLN C 1 145 ? -26.227 -26.148 52.76   1    136.07 ? 134 GLN C CD  1 -0.24  -0.24  0.132  
ATOM   7240  O  OE1 . GLN C 1 145 ? -27.169 -26.562 52.06   1    140.78 ? 134 GLN C OE1 1 -0.249 -0.243 0.13   
ATOM   7241  N  NE2 . GLN C 1 145 ? -26.408 -25.522 53.934  1    128.33 ? 134 GLN C NE2 1 -0.242 -0.234 0.135  
ATOM   7242  N  N   . ALA C 1 146 ? -22.173 -24.865 50.076  1    106.29 ? 135 ALA C N   1 -0.203 -0.228 0.125  
ATOM   7243  C  CA  . ALA C 1 146 ? -21.942 -25.144 48.661  1    105.66 ? 135 ALA C CA  1 -0.201 -0.23  0.121  
ATOM   7244  C  C   . ALA C 1 146 ? -20.667 -25.945 48.422  1    107.36 ? 135 ALA C C   1 -0.189 -0.238 0.121  
ATOM   7245  O  O   . ALA C 1 146 ? -20.607 -26.732 47.479  1    110.6  ? 135 ALA C O   1 -0.189 -0.245 0.119  
ATOM   7246  C  CB  . ALA C 1 146 ? -21.875 -23.833 47.884  1    107.78 ? 135 ALA C CB  1 -0.2   -0.218 0.12   
ATOM   7247  N  N   . LYS C 1 147 ? -19.641 -25.756 49.255  1    112.22 ? 136 LYS C N   1 -0.18  -0.236 0.123  
ATOM   7248  C  CA  . LYS C 1 147 ? -18.34  -26.383 49.019  1    114.73 ? 136 LYS C CA  1 -0.168 -0.242 0.122  
ATOM   7249  C  C   . LYS C 1 147 ? -18.439 -27.892 48.785  1    112.36 ? 136 LYS C C   1 -0.169 -0.256 0.122  
ATOM   7250  O  O   . LYS C 1 147 ? -17.587 -28.466 48.1    1    109.87 ? 136 LYS C O   1 -0.161 -0.261 0.12   
ATOM   7251  C  CB  . LYS C 1 147 ? -17.409 -26.078 50.212  1    118.44 ? 136 LYS C CB  1 -0.16  -0.239 0.125  
ATOM   7252  C  CG  . LYS C 1 147 ? -15.939 -26.491 50.042  1    116.47 ? 136 LYS C CG  1 -0.146 -0.243 0.125  
ATOM   7253  C  CD  . LYS C 1 147 ? -15.405 -26.093 48.668  1    126.18 ? 136 LYS C CD  1 -0.141 -0.239 0.122  
ATOM   7254  C  CE  . LYS C 1 147 ? -14.045 -26.739 48.382  1    129.32 ? 136 LYS C CE  1 -0.129 -0.245 0.121  
ATOM   7255  N  NZ  . LYS C 1 147 ? -13.595 -26.513 46.977  1    102.51 ? 136 LYS C NZ  1 -0.125 -0.243 0.117  
ATOM   7256  N  N   . HIS C 1 148 ? -19.464 -28.553 49.334  1    118.25 ? 137 HIS C N   1 -0.178 -0.262 0.123  
ATOM   7257  C  CA  . HIS C 1 148 ? -19.511 -30.015 49.274  1    119.89 ? 137 HIS C CA  1 -0.179 -0.275 0.123  
ATOM   7258  C  C   . HIS C 1 148 ? -19.738 -30.499 47.853  1    118.81 ? 137 HIS C C   1 -0.181 -0.279 0.119  
ATOM   7259  O  O   . HIS C 1 148 ? -18.999 -31.353 47.353  1    126.4  ? 137 HIS C O   1 -0.174 -0.287 0.118  
ATOM   7260  C  CB  . HIS C 1 148 ? -20.596 -30.568 50.206  1    130.04 ? 137 HIS C CB  1 -0.189 -0.28  0.125  
ATOM   7261  C  CG  . HIS C 1 148 ? -20.755 -32.065 50.14   1    132.94 ? 137 HIS C CG  1 -0.19  -0.294 0.125  
ATOM   7262  N  ND1 . HIS C 1 148 ? -19.724 -32.914 49.786  1    127.09 ? 137 HIS C ND1 1 -0.181 -0.302 0.124  
ATOM   7263  C  CD2 . HIS C 1 148 ? -21.828 -32.861 50.386  1    131.12 ? 137 HIS C CD2 1 -0.2   -0.301 0.126  
ATOM   7264  C  CE1 . HIS C 1 148 ? -20.155 -34.165 49.812  1    126.62 ? 137 HIS C CE1 1 -0.185 -0.313 0.124  
ATOM   7265  N  NE2 . HIS C 1 148 ? -21.429 -34.16  50.169  1    127.23 ? 137 HIS C NE2 1 -0.196 -0.313 0.125  
ATOM   7266  N  N   . PHE C 1 149 ? -20.76  -29.969 47.182  1    121.02 ? 138 PHE C N   1 -0.19  -0.275 0.118  
ATOM   7267  C  CA  . PHE C 1 149 ? -21.078 -30.36  45.817  1    111.39 ? 138 PHE C CA  1 -0.193 -0.278 0.114  
ATOM   7268  C  C   . PHE C 1 149 ? -20.849 -29.235 44.81   1    110.77 ? 138 PHE C C   1 -0.191 -0.268 0.112  
ATOM   7269  O  O   . PHE C 1 149 ? -21.48  -29.225 43.751  1    119.42 ? 138 PHE C O   1 -0.197 -0.268 0.109  
ATOM   7270  C  CB  . PHE C 1 149 ? -22.525 -30.84  45.739  1    113.38 ? 138 PHE C CB  1 -0.206 -0.283 0.114  
ATOM   7271  C  CG  . PHE C 1 149 ? -22.739 -32.228 46.259  1    118.98 ? 138 PHE C CG  1 -0.208 -0.295 0.115  
ATOM   7272  C  CD1 . PHE C 1 149 ? -21.879 -33.251 45.891  1    117.03 ? 138 PHE C CD1 1 -0.201 -0.305 0.115  
ATOM   7273  C  CD2 . PHE C 1 149 ? -23.797 -32.512 47.117  1    121.2  ? 138 PHE C CD2 1 -0.218 -0.298 0.118  
ATOM   7274  C  CE1 . PHE C 1 149 ? -22.071 -34.539 46.361  1    115.55 ? 138 PHE C CE1 1 -0.202 -0.317 0.116  
ATOM   7275  C  CE2 . PHE C 1 149 ? -23.998 -33.804 47.597  1    118.21 ? 138 PHE C CE2 1 -0.22  -0.31  0.119  
ATOM   7276  C  CZ  . PHE C 1 149 ? -23.131 -34.819 47.215  1    119.57 ? 138 PHE C CZ  1 -0.212 -0.319 0.118  
ATOM   7277  N  N   . GLY C 1 150 ? -19.99  -28.272 45.122  1    103.44 ? 139 GLY C N   1 -0.183 -0.259 0.113  
ATOM   7278  C  CA  . GLY C 1 150 ? -19.715 -27.183 44.204  1    101.38 ? 139 GLY C CA  1 -0.181 -0.249 0.11   
ATOM   7279  C  C   . GLY C 1 150 ? -20.715 -26.042 44.141  1    102.67 ? 139 GLY C C   1 -0.19  -0.239 0.11   
ATOM   7280  O  O   . GLY C 1 150 ? -20.323 -24.917 43.812  1    104.95 ? 139 GLY C O   1 -0.186 -0.228 0.109  
ATOM   7281  N  N   . PHE C 1 151 ? -21.996 -26.297 44.428  1    102.31 ? 140 PHE C N   1 -0.202 -0.241 0.111  
ATOM   7282  C  CA  . PHE C 1 151 ? -23.013 -25.248 44.407  1    102.6  ? 140 PHE C CA  1 -0.211 -0.231 0.111  
ATOM   7283  C  C   . PHE C 1 151 ? -24.269 -25.734 45.12   1    103.93 ? 140 PHE C C   1 -0.222 -0.236 0.113  
ATOM   7284  O  O   . PHE C 1 151 ? -24.62  -26.913 45.039  1    107.36 ? 140 PHE C O   1 -0.226 -0.247 0.112  
ATOM   7285  C  CB  . PHE C 1 151 ? -23.352 -24.81  42.967  1    110.27 ? 140 PHE C CB  1 -0.214 -0.227 0.107  
ATOM   7286  C  CG  . PHE C 1 151 ? -23.582 -25.958 42.005  1    108.03 ? 140 PHE C CG  1 -0.216 -0.238 0.105  
ATOM   7287  C  CD1 . PHE C 1 151 ? -22.501 -26.614 41.409  1    109.16 ? 140 PHE C CD1 1 -0.206 -0.244 0.103  
ATOM   7288  C  CD2 . PHE C 1 151 ? -24.872 -26.377 41.691  1    104.78 ? 140 PHE C CD2 1 -0.228 -0.242 0.104  
ATOM   7289  C  CE1 . PHE C 1 151 ? -22.695 -27.682 40.536  1    109.58 ? 140 PHE C CE1 1 -0.208 -0.254 0.101  
ATOM   7290  C  CE2 . PHE C 1 151 ? -25.08  -27.441 40.811  1    109.23 ? 140 PHE C CE2 1 -0.23  -0.251 0.102  
ATOM   7291  C  CZ  . PHE C 1 151 ? -23.986 -28.095 40.234  1    110.47 ? 140 PHE C CZ  1 -0.22  -0.257 0.1    
ATOM   7292  N  N   . LYS C 1 152 ? -24.936 -24.816 45.813  1    104.92 ? 141 LYS C N   1 -0.229 -0.227 0.114  
ATOM   7293  C  CA  . LYS C 1 152 ? -26.185 -25.062 46.521  1    108.52 ? 141 LYS C CA  1 -0.24  -0.23  0.116  
ATOM   7294  C  C   . LYS C 1 152 ? -27.225 -24.098 45.965  1    112.55 ? 141 LYS C C   1 -0.249 -0.221 0.115  
ATOM   7295  O  O   . LYS C 1 152 ? -26.884 -23.01  45.492  1    114.56 ? 141 LYS C O   1 -0.246 -0.211 0.114  
ATOM   7296  C  CB  . LYS C 1 152 ? -25.983 -24.874 48.065  1    122.36 ? 141 LYS C CB  1 -0.238 -0.228 0.12   
ATOM   7297  C  CG  . LYS C 1 152 ? -27.112 -25.293 49.076  1    120.29 ? 141 LYS C CG  1 -0.248 -0.232 0.123  
ATOM   7298  C  CD  . LYS C 1 152 ? -27.58  -26.772 49.008  1    126.5  ? 141 LYS C CD  1 -0.253 -0.245 0.122  
ATOM   7299  C  CE  . LYS C 1 152 ? -26.468 -27.804 48.744  1    127.02 ? 141 LYS C CE  1 -0.243 -0.255 0.122  
ATOM   7300  N  NZ  . LYS C 1 152 ? -27.025 -29.054 48.088  1    116.12 ? 141 LYS C NZ  1 -0.248 -0.266 0.12   
ATOM   7301  N  N   . GLN C 1 153 ? -28.491 -24.503 45.987  1    113.72 ? 142 GLN C N   1 -0.261 -0.225 0.115  
ATOM   7302  C  CA  . GLN C 1 153 ? -29.567 -23.703 45.422  1    117.59 ? 142 GLN C CA  1 -0.271 -0.217 0.113  
ATOM   7303  C  C   . GLN C 1 153 ? -30.373 -23.009 46.516  1    117.77 ? 142 GLN C C   1 -0.278 -0.211 0.116  
ATOM   7304  O  O   . GLN C 1 153 ? -30.426 -23.476 47.651  1    127.88 ? 142 GLN C O   1 -0.279 -0.215 0.119  
ATOM   7305  C  CB  . GLN C 1 153 ? -30.482 -24.577 44.577  1    125.43 ? 142 GLN C CB  1 -0.279 -0.225 0.111  
ATOM   7306  C  CG  . GLN C 1 153 ? -31.389 -23.814 43.648  1    125.64 ? 142 GLN C CG  1 -0.288 -0.218 0.109  
ATOM   7307  C  CD  . GLN C 1 153 ? -32.099 -24.751 42.72   1    122.88 ? 142 GLN C CD  1 -0.294 -0.227 0.107  
ATOM   7308  O  OE1 . GLN C 1 153 ? -31.698 -25.909 42.586  1    118.25 ? 142 GLN C OE1 1 -0.29  -0.237 0.106  
ATOM   7309  N  NE2 . GLN C 1 153 ? -33.167 -24.275 42.084  1    125.22 ? 142 GLN C NE2 1 -0.304 -0.222 0.105  
ATOM   7310  N  N   . LEU C 1 154 ? -31.014 -21.882 46.168  1    116.99 ? 143 LEU C N   1 -0.284 -0.201 0.115  
ATOM   7311  C  CA  . LEU C 1 154 ? -31.725 -21.053 47.134  1    114.73 ? 143 LEU C CA  1 -0.291 -0.193 0.118  
ATOM   7312  C  C   . LEU C 1 154 ? -33.226 -21.172 46.853  1    125.2  ? 143 LEU C C   1 -0.304 -0.194 0.117  
ATOM   7313  O  O   . LEU C 1 154 ? -33.846 -22.167 47.261  1    132.75 ? 143 LEU C O   1 -0.31  -0.203 0.118  
ATOM   7314  C  CB  . LEU C 1 154 ? -31.272 -19.6   47.047  1    113.74 ? 143 LEU C CB  1 -0.287 -0.18  0.117  
ATOM   7315  C  CG  . LEU C 1 154 ? -30.121 -19.121 47.909  1    113.42 ? 143 LEU C CG  1 -0.276 -0.175 0.12   
ATOM   7316  C  CD1 . LEU C 1 154 ? -30.688 -18.724 49.237  1    120.43 ? 143 LEU C CD1 1 -0.281 -0.172 0.123  
ATOM   7317  C  CD2 . LEU C 1 154 ? -29.08  -20.211 48.056  1    113.35 ? 143 LEU C CD2 1 -0.266 -0.185 0.12   
ATOM   7318  N  N   . ASN C 1 155 ? -33.84  -20.188 46.216  1    132.08 ? 144 ASN C N   1 -0.31  -0.185 0.115  
ATOM   7319  C  CA  . ASN C 1 155 ? -35.128 -20.389 45.553  1    137.71 ? 144 ASN C CA  1 -0.322 -0.187 0.114  
ATOM   7320  C  C   . ASN C 1 155 ? -34.886 -21.172 44.266  1    127.38 ? 144 ASN C C   1 -0.32  -0.194 0.111  
ATOM   7321  O  O   . ASN C 1 155 ? -33.806 -21.721 44.03   1    125.07 ? 144 ASN C O   1 -0.31  -0.199 0.11   
ATOM   7322  C  CB  . ASN C 1 155 ? -35.816 -19.051 45.286  1    137.63 ? 144 ASN C CB  1 -0.328 -0.175 0.113  
ATOM   7323  C  CG  . ASN C 1 155 ? -36.289 -18.367 46.563  1    133.01 ? 144 ASN C CG  1 -0.333 -0.168 0.116  
ATOM   7324  O  OD1 . ASN C 1 155 ? -36.009 -18.843 47.674  1    130.18 ? 144 ASN C OD1 1 -0.33  -0.173 0.119  
ATOM   7325  N  ND2 . ASN C 1 155 ? -37     -17.249 46.413  1    122.1  ? 144 ASN C ND2 1 -0.339 -0.158 0.116  
ATOM   7326  N  N   . ALA C 1 156 ? -35.902 -21.223 43.41   1    130.84 ? 145 ALA C N   1 -0.329 -0.194 0.108  
ATOM   7327  C  CA  . ALA C 1 156 ? -35.73  -21.917 42.138  1    135.03 ? 145 ALA C CA  1 -0.327 -0.201 0.105  
ATOM   7328  C  C   . ALA C 1 156 ? -34.82  -21.165 41.168  1    133.5  ? 145 ALA C C   1 -0.319 -0.194 0.103  
ATOM   7329  O  O   . ALA C 1 156 ? -34.417 -21.747 40.151  1    133.9  ? 145 ALA C O   1 -0.315 -0.199 0.1    
ATOM   7330  C  CB  . ALA C 1 156 ? -37.092 -22.172 41.484  1    131.69 ? 145 ALA C CB  1 -0.34  -0.203 0.104  
ATOM   7331  N  N   . ASP C 1 157 ? -34.469 -19.903 41.46   1    134.56 ? 146 ASP C N   1 -0.316 -0.182 0.104  
ATOM   7332  C  CA  . ASP C 1 157 ? -33.728 -19.063 40.52   1    128.95 ? 146 ASP C CA  1 -0.309 -0.175 0.101  
ATOM   7333  C  C   . ASP C 1 157 ? -32.446 -18.476 41.108  1    123.64 ? 146 ASP C C   1 -0.297 -0.169 0.103  
ATOM   7334  O  O   . ASP C 1 157 ? -31.913 -17.515 40.546  1    111.47 ? 146 ASP C O   1 -0.292 -0.161 0.101  
ATOM   7335  C  CB  . ASP C 1 157 ? -34.605 -17.916 40.004  1    131.4  ? 146 ASP C CB  1 -0.317 -0.164 0.1    
ATOM   7336  C  CG  . ASP C 1 157 ? -35.911 -18.401 39.378  1    142.97 ? 146 ASP C CG  1 -0.329 -0.169 0.098  
ATOM   7337  O  OD1 . ASP C 1 157 ? -36.818 -18.8   40.152  1    146.91 ? 146 ASP C OD1 1 -0.337 -0.172 0.1    
ATOM   7338  O  OD2 . ASP C 1 157 ? -36.035 -18.367 38.124  1    137.39 ? 146 ASP C OD2 1 -0.33  -0.168 0.095  
ATOM   7339  N  N   . LEU C 1 158 ? -31.946 -19.011 42.23   1    124.93 ? 147 LEU C N   1 -0.293 -0.174 0.105  
ATOM   7340  C  CA  . LEU C 1 158 ? -30.682 -18.575 42.819  1    109.7  ? 147 LEU C CA  1 -0.281 -0.17  0.107  
ATOM   7341  C  C   . LEU C 1 158 ? -29.781 -19.777 43.041  1    105.57 ? 147 LEU C C   1 -0.273 -0.181 0.107  
ATOM   7342  O  O   . LEU C 1 158 ? -30.25  -20.857 43.405  1    113.04 ? 147 LEU C O   1 -0.277 -0.191 0.108  
ATOM   7343  C  CB  . LEU C 1 158 ? -30.904 -17.857 44.136  1    113.59 ? 147 LEU C CB  1 -0.283 -0.164 0.11   
ATOM   7344  C  CG  . LEU C 1 158 ? -30.856 -16.339 44.237  1    111.13 ? 147 LEU C CG  1 -0.283 -0.15  0.11   
ATOM   7345  C  CD1 . LEU C 1 158 ? -31.66  -15.677 43.16   1    111.97 ? 147 LEU C CD1 1 -0.29  -0.144 0.108  
ATOM   7346  C  CD2 . LEU C 1 158 ? -31.381 -15.949 45.603  1    106.62 ? 147 LEU C CD2 1 -0.288 -0.146 0.114  
ATOM   7347  N  N   . VAL C 1 159 ? -28.492 -19.59  42.79   1    94.32  ? 148 VAL C N   1 -0.261 -0.18  0.107  
ATOM   7348  C  CA  . VAL C 1 159 ? -27.478 -20.628 42.957  1    100.18 ? 148 VAL C CA  1 -0.252 -0.189 0.107  
ATOM   7349  C  C   . VAL C 1 159 ? -26.24  -19.909 43.459  1    104.72 ? 148 VAL C C   1 -0.24  -0.182 0.109  
ATOM   7350  O  O   . VAL C 1 159 ? -25.964 -18.78  43.039  1    102.38 ? 148 VAL C O   1 -0.238 -0.172 0.107  
ATOM   7351  C  CB  . VAL C 1 159 ? -27.164 -21.399 41.644  1    110.21 ? 148 VAL C CB  1 -0.249 -0.196 0.104  
ATOM   7352  C  CG1 . VAL C 1 159 ? -26.176 -22.546 41.898  1    109.14 ? 148 VAL C CG1 1 -0.24  -0.207 0.105  
ATOM   7353  C  CG2 . VAL C 1 159 ? -28.437 -21.933 40.955  1    110.62 ? 148 VAL C CG2 1 -0.261 -0.201 0.102  
ATOM   7354  N  N   . VAL C 1 160 ? -25.51  -20.538 44.372  1    107.17 ? 149 VAL C N   1 -0.234 -0.188 0.111  
ATOM   7355  C  CA  . VAL C 1 160 ? -24.377 -19.891 45.02   1    103.2  ? 149 VAL C CA  1 -0.223 -0.182 0.112  
ATOM   7356  C  C   . VAL C 1 160 ? -23.224 -20.881 45.086  1    103.33 ? 149 VAL C C   1 -0.213 -0.191 0.113  
ATOM   7357  O  O   . VAL C 1 160 ? -23.425 -22.052 45.42   1    103.75 ? 149 VAL C O   1 -0.215 -0.202 0.113  
ATOM   7358  C  CB  . VAL C 1 160 ? -24.755 -19.377 46.422  1    104.27 ? 149 VAL C CB  1 -0.227 -0.178 0.116  
ATOM   7359  C  CG1 . VAL C 1 160 ? -25.496 -20.45  47.174  1    109.26 ? 149 VAL C CG1 1 -0.234 -0.187 0.118  
ATOM   7360  C  CG2 . VAL C 1 160 ? -23.523 -18.973 47.193  1    104.07 ? 149 VAL C CG2 1 -0.216 -0.174 0.118  
ATOM   7361  N  N   . THR C 1 161 ? -22.029 -20.418 44.741  1    103.76 ? 150 THR C N   1 -0.202 -0.187 0.112  
ATOM   7362  C  CA  . THR C 1 161 ? -20.799 -21.196 44.785  1    103.18 ? 150 THR C CA  1 -0.191 -0.194 0.112  
ATOM   7363  C  C   . THR C 1 161 ? -19.996 -20.851 46.044  1    107.61 ? 150 THR C C   1 -0.183 -0.191 0.115  
ATOM   7364  O  O   . THR C 1 161 ? -20.35  -19.935 46.799  1    102.08 ? 150 THR C O   1 -0.186 -0.183 0.117  
ATOM   7365  C  CB  . THR C 1 161 ? -19.981 -20.939 43.51   1    102.48 ? 150 THR C CB  1 -0.183 -0.192 0.109  
ATOM   7366  O  OG1 . THR C 1 161 ? -19.113 -19.813 43.689  1    97.99  ? 150 THR C OG1 1 -0.175 -0.182 0.109  
ATOM   7367  C  CG2 . THR C 1 161 ? -20.914 -20.656 42.328  1    108.31 ? 150 THR C CG2 1 -0.192 -0.189 0.106  
ATOM   7368  N  N   . PRO C 1 162 ? -18.921 -21.598 46.333  1    105.21 ? 151 PRO C N   1 -0.173 -0.198 0.116  
ATOM   7369  C  CA  . PRO C 1 162 ? -18.134 -21.276 47.533  1    101.35 ? 151 PRO C CA  1 -0.166 -0.195 0.119  
ATOM   7370  C  C   . PRO C 1 162 ? -17.557 -19.867 47.563  1    99.41  ? 151 PRO C C   1 -0.161 -0.182 0.119  
ATOM   7371  O  O   . PRO C 1 162 ? -17.388 -19.313 48.657  1    104.77 ? 151 PRO C O   1 -0.159 -0.177 0.121  
ATOM   7372  C  CB  . PRO C 1 162 ? -17.036 -22.347 47.513  1    100.24 ? 151 PRO C CB  1 -0.156 -0.205 0.119  
ATOM   7373  C  CG  . PRO C 1 162 ? -17.739 -23.524 46.988  1    103.19 ? 151 PRO C CG  1 -0.163 -0.216 0.117  
ATOM   7374  C  CD  . PRO C 1 162 ? -18.623 -22.967 45.869  1    106.32 ? 151 PRO C CD  1 -0.171 -0.21  0.115  
ATOM   7375  N  N   . LYS C 1 163 ? -17.255 -19.255 46.424  1    89.85  ? 152 LYS C N   1 -0.158 -0.176 0.116  
ATOM   7376  C  CA  . LYS C 1 163 ? -16.671 -17.923 46.458  1    90.61  ? 152 LYS C CA  1 -0.153 -0.164 0.116  
ATOM   7377  C  C   . LYS C 1 163 ? -17.67  -16.831 46.126  1    92.73  ? 152 LYS C C   1 -0.162 -0.154 0.115  
ATOM   7378  O  O   . LYS C 1 163 ? -17.253 -15.691 45.878  1    90.01  ? 152 LYS C O   1 -0.158 -0.144 0.115  
ATOM   7379  C  CB  . LYS C 1 163 ? -15.484 -17.826 45.515  1    90.24  ? 152 LYS C CB  1 -0.142 -0.163 0.114  
ATOM   7380  C  CG  . LYS C 1 163 ? -14.618 -19.071 45.492  1    99.84  ? 152 LYS C CG  1 -0.134 -0.175 0.114  
ATOM   7381  C  CD  . LYS C 1 163 ? -13.809 -19.218 46.746  1    107.57 ? 152 LYS C CD  1 -0.127 -0.176 0.117  
ATOM   7382  C  CE  . LYS C 1 163 ? -12.91  -18.024 46.923  1    110.98 ? 152 LYS C CE  1 -0.118 -0.165 0.117  
ATOM   7383  N  NZ  . LYS C 1 163 ? -12.374 -17.548 45.611  1    121.18 ? 152 LYS C NZ  1 -0.113 -0.161 0.114  
ATOM   7384  N  N   . THR C 1 164 ? -18.973 -17.135 46.148  1    91.03  ? 153 THR C N   1 -0.174 -0.157 0.115  
ATOM   7385  C  CA  . THR C 1 164 ? -19.956 -16.15  45.703  1    93.15  ? 153 THR C CA  1 -0.183 -0.148 0.114  
ATOM   7386  C  C   . THR C 1 164 ? -19.911 -14.906 46.573  1    95.25  ? 153 THR C C   1 -0.182 -0.137 0.116  
ATOM   7387  O  O   . THR C 1 164 ? -19.9   -13.774 46.067  1    93.82  ? 153 THR C O   1 -0.182 -0.126 0.115  
ATOM   7388  C  CB  . THR C 1 164 ? -21.362 -16.749 45.697  1    96.34  ? 153 THR C CB  1 -0.196 -0.153 0.114  
ATOM   7389  O  OG1 . THR C 1 164 ? -21.532 -17.578 44.528  1    103.39 ? 153 THR C OG1 1 -0.197 -0.161 0.111  
ATOM   7390  C  CG2 . THR C 1 164 ? -22.398 -15.636 45.686  1    86.84  ? 153 THR C CG2 1 -0.205 -0.143 0.114  
ATOM   7391  N  N   . PHE C 1 165 ? -19.864 -15.103 47.891  1    104.47 ? 154 PHE C N   1 -0.182 -0.138 0.12   
ATOM   7392  C  CA  . PHE C 1 165 ? -19.767 -13.99  48.83   1    99.05  ? 154 PHE C CA  1 -0.181 -0.128 0.122  
ATOM   7393  C  C   . PHE C 1 165 ? -18.545 -13.126 48.543  1    97.07  ? 154 PHE C C   1 -0.17  -0.12  0.121  
ATOM   7394  O  O   . PHE C 1 165 ? -18.663 -11.916 48.298  1    93.38  ? 154 PHE C O   1 -0.171 -0.109 0.121  
ATOM   7395  C  CB  . PHE C 1 165 ? -19.71  -14.533 50.248  1    97.77  ? 154 PHE C CB  1 -0.181 -0.133 0.125  
ATOM   7396  C  CG  . PHE C 1 165 ? -19.755 -13.467 51.301  1    104.43 ? 154 PHE C CG  1 -0.181 -0.123 0.128  
ATOM   7397  C  CD1 . PHE C 1 165 ? -20.974 -12.987 51.761  1    101.28 ? 154 PHE C CD1 1 -0.192 -0.119 0.129  
ATOM   7398  C  CD2 . PHE C 1 165 ? -18.586 -12.939 51.828  1    98.11  ? 154 PHE C CD2 1 -0.17  -0.119 0.129  
ATOM   7399  C  CE1 . PHE C 1 165 ? -21.022 -12.013 52.718  1    95.11  ? 154 PHE C CE1 1 -0.193 -0.11  0.132  
ATOM   7400  C  CE2 . PHE C 1 165 ? -18.638 -11.962 52.788  1    99.57  ? 154 PHE C CE2 1 -0.171 -0.11  0.132  
ATOM   7401  C  CZ  . PHE C 1 165 ? -19.855 -11.501 53.236  1    98.05  ? 154 PHE C CZ  1 -0.182 -0.105 0.133  
ATOM   7402  N  N   . GLU C 1 166 ? -17.356 -13.735 48.584  1    93.97  ? 155 GLU C N   1 -0.159 -0.126 0.121  
ATOM   7403  C  CA  . GLU C 1 166 ? -16.128 -13.01  48.278  1    88.97  ? 155 GLU C CA  1 -0.148 -0.119 0.121  
ATOM   7404  C  C   . GLU C 1 166 ? -16.273 -12.212 46.99   1    100.32 ? 155 GLU C C   1 -0.149 -0.112 0.117  
ATOM   7405  O  O   . GLU C 1 166 ? -15.991 -11.007 46.957  1    100.73 ? 155 GLU C O   1 -0.147 -0.101 0.117  
ATOM   7406  C  CB  . GLU C 1 166 ? -14.969 -13.994 48.188  1    85.62  ? 155 GLU C CB  1 -0.137 -0.128 0.12   
ATOM   7407  C  CG  . GLU C 1 166 ? -13.629 -13.353 47.928  1    93.89  ? 155 GLU C CG  1 -0.125 -0.122 0.12   
ATOM   7408  C  CD  . GLU C 1 166 ? -12.493 -14.372 47.919  1    103.02 ? 155 GLU C CD  1 -0.114 -0.132 0.12   
ATOM   7409  O  OE1 . GLU C 1 166 ? -12.696 -15.486 48.462  1    108.71 ? 155 GLU C OE1 1 -0.116 -0.142 0.121  
ATOM   7410  O  OE2 . GLU C 1 166 ? -11.401 -14.063 47.385  1    104.53 ? 155 GLU C OE2 1 -0.104 -0.129 0.118  
ATOM   7411  N  N   . ILE C 1 167 ? -16.761 -12.862 45.927  1    98.47  ? 156 ILE C N   1 -0.154 -0.118 0.115  
ATOM   7412  C  CA  . ILE C 1 167 ? -16.941 -12.185 44.643  1    97.75  ? 156 ILE C CA  1 -0.155 -0.112 0.111  
ATOM   7413  C  C   . ILE C 1 167 ? -17.852 -10.975 44.799  1    102.09 ? 156 ILE C C   1 -0.164 -0.101 0.112  
ATOM   7414  O  O   . ILE C 1 167 ? -17.517 -9.86   44.37   1    105.62 ? 156 ILE C O   1 -0.161 -0.09  0.111  
ATOM   7415  C  CB  . ILE C 1 167 ? -17.503 -13.17  43.601  1    99.64  ? 156 ILE C CB  1 -0.16  -0.121 0.109  
ATOM   7416  C  CG1 . ILE C 1 167 ? -16.435 -14.151 43.157  1    94.04  ? 156 ILE C CG1 1 -0.151 -0.13  0.108  
ATOM   7417  C  CG2 . ILE C 1 167 ? -18.071 -12.444 42.385  1    94.7   ? 156 ILE C CG2 1 -0.166 -0.114 0.106  
ATOM   7418  C  CD1 . ILE C 1 167 ? -17.03  -15.216 42.324  1    93.88  ? 156 ILE C CD1 1 -0.156 -0.139 0.106  
ATOM   7419  N  N   . LEU C 1 168 ? -19.032 -11.186 45.392  1    99.89  ? 157 LEU C N   1 -0.174 -0.103 0.113  
ATOM   7420  C  CA  . LEU C 1 168 ? -19.981 -10.094 45.58   1    100.53 ? 157 LEU C CA  1 -0.183 -0.093 0.114  
ATOM   7421  C  C   . LEU C 1 168 ? -19.347 -8.932  46.331  1    103.18 ? 157 LEU C C   1 -0.177 -0.082 0.116  
ATOM   7422  O  O   . LEU C 1 168 ? -19.537 -7.762  45.958  1    95.41  ? 157 LEU C O   1 -0.179 -0.071 0.115  
ATOM   7423  C  CB  . LEU C 1 168 ? -21.219 -10.61  46.312  1    97.49  ? 157 LEU C CB  1 -0.194 -0.097 0.116  
ATOM   7424  C  CG  . LEU C 1 168 ? -22.179 -11.254 45.316  1    100.66 ? 157 LEU C CG  1 -0.203 -0.103 0.113  
ATOM   7425  C  CD1 . LEU C 1 168 ? -23.431 -11.774 45.993  1    95.78  ? 157 LEU C CD1 1 -0.215 -0.108 0.115  
ATOM   7426  C  CD2 . LEU C 1 168 ? -22.507 -10.229 44.214  1    97.78  ? 157 LEU C CD2 1 -0.206 -0.094 0.11   
ATOM   7427  N  N   . ILE C 1 169 ? -18.564 -9.235  47.376  1    98.97  ? 158 ILE C N   1 -0.17  -0.085 0.118  
ATOM   7428  C  CA  . ILE C 1 169 ? -17.925 -8.178  48.154  1    101.52 ? 158 ILE C CA  1 -0.164 -0.075 0.12   
ATOM   7429  C  C   . ILE C 1 169 ? -16.807 -7.522  47.351  1    107.07 ? 158 ILE C C   1 -0.154 -0.069 0.118  
ATOM   7430  O  O   . ILE C 1 169 ? -16.59  -6.307  47.451  1    109.43 ? 158 ILE C O   1 -0.152 -0.058 0.118  
ATOM   7431  C  CB  . ILE C 1 169 ? -17.423 -8.713  49.509  1    102.83 ? 158 ILE C CB  1 -0.16  -0.08  0.124  
ATOM   7432  C  CG1 . ILE C 1 169 ? -18.598 -8.867  50.474  1    95.62  ? 158 ILE C CG1 1 -0.17  -0.081 0.126  
ATOM   7433  C  CG2 . ILE C 1 169 ? -16.361 -7.785  50.126  1    95.44  ? 158 ILE C CG2 1 -0.15  -0.071 0.125  
ATOM   7434  C  CD1 . ILE C 1 169 ? -19.583 -7.712  50.379  1    89.56  ? 158 ILE C CD1 1 -0.179 -0.071 0.126  
ATOM   7435  N  N   . ARG C 1 170 ? -16.082 -8.305  46.541  1    102.52 ? 159 ARG C N   1 -0.147 -0.076 0.116  
ATOM   7436  C  CA  . ARG C 1 170 ? -15.017 -7.696  45.752  1    100.63 ? 159 ARG C CA  1 -0.138 -0.071 0.114  
ATOM   7437  C  C   . ARG C 1 170 ? -15.595 -6.735  44.729  1    101.95 ? 159 ARG C C   1 -0.143 -0.062 0.112  
ATOM   7438  O  O   . ARG C 1 170 ? -15.086 -5.618  44.582  1    101.91 ? 159 ARG C O   1 -0.138 -0.051 0.111  
ATOM   7439  C  CB  . ARG C 1 170 ? -14.14  -8.767  45.101  1    98.98  ? 159 ARG C CB  1 -0.13  -0.08  0.113  
ATOM   7440  C  CG  . ARG C 1 170 ? -13.082 -9.318  46.07   1    103.28 ? 159 ARG C CG  1 -0.12  -0.085 0.115  
ATOM   7441  C  CD  . ARG C 1 170 ? -12.054 -10.236 45.413  1    104.3  ? 159 ARG C CD  1 -0.11  -0.094 0.113  
ATOM   7442  N  NE  . ARG C 1 170 ? -10.698 -9.964  45.885  1    107.74 ? 159 ARG C NE  1 -0.098 -0.091 0.115  
ATOM   7443  C  CZ  . ARG C 1 170 ? -10.106 -10.594 46.892  1    111.29 ? 159 ARG C CZ  1 -0.093 -0.097 0.117  
ATOM   7444  N  NH1 . ARG C 1 170 ? -10.715 -11.568 47.551  1    108.56 ? 159 ARG C NH1 1 -0.098 -0.106 0.119  
ATOM   7445  N  NH2 . ARG C 1 170 ? -8.87   -10.239 47.248  1    113.12 ? 159 ARG C NH2 1 -0.081 -0.094 0.118  
ATOM   7446  N  N   . ASP C 1 171 ? -16.689 -7.131  44.05   1    110.99 ? 160 ASP C N   1 -0.153 -0.065 0.11   
ATOM   7447  C  CA  . ASP C 1 171 ? -17.337 -6.251  43.07   1    109.32 ? 160 ASP C CA  1 -0.159 -0.057 0.108  
ATOM   7448  C  C   . ASP C 1 171 ? -17.814 -4.965  43.733  1    111.37 ? 160 ASP C C   1 -0.163 -0.045 0.109  
ATOM   7449  O  O   . ASP C 1 171 ? -17.658 -3.874  43.166  1    109.99 ? 160 ASP C O   1 -0.162 -0.036 0.108  
ATOM   7450  C  CB  . ASP C 1 171 ? -18.511 -6.974  42.382  1    101.94 ? 160 ASP C CB  1 -0.17  -0.064 0.106  
ATOM   7451  C  CG  . ASP C 1 171 ? -19.078 -6.207  41.148  1    121.95 ? 160 ASP C CG  1 -0.175 -0.057 0.103  
ATOM   7452  O  OD1 . ASP C 1 171 ? -19.285 -4.973  41.22   1    119.77 ? 160 ASP C OD1 1 -0.177 -0.046 0.103  
ATOM   7453  O  OD2 . ASP C 1 171 ? -19.33  -6.845  40.089  1    119.24 ? 160 ASP C OD2 1 -0.177 -0.063 0.1    
ATOM   7454  N  N   . CYS C 1 172 ? -18.376 -5.076  44.95   1    105.6  ? 161 CYS C N   1 -0.168 -0.047 0.112  
ATOM   7455  C  CA  . CYS C 1 172 ? -18.894 -3.901  45.647  1    104.32 ? 161 CYS C CA  1 -0.173 -0.036 0.114  
ATOM   7456  C  C   . CYS C 1 172 ? -17.772 -2.983  46.107  1    105.97 ? 161 CYS C C   1 -0.163 -0.027 0.115  
ATOM   7457  O  O   . CYS C 1 172 ? -17.911 -1.754  46.077  1    104.37 ? 161 CYS C O   1 -0.164 -0.016 0.115  
ATOM   7458  C  CB  . CYS C 1 172 ? -19.732 -4.325  46.846  1    108.11 ? 161 CYS C CB  1 -0.181 -0.04  0.117  
ATOM   7459  S  SG  . CYS C 1 172 ? -21.351 -4.941  46.44   1    115.51 ? 161 CYS C SG  1 -0.196 -0.045 0.116  
ATOM   7460  N  N   . ALA C 1 173 ? -16.66  -3.56   46.557  1    103.49 ? 162 ALA C N   1 -0.153 -0.033 0.116  
ATOM   7461  C  CA  . ALA C 1 173 ? -15.54  -2.738  46.989  1    105.94 ? 162 ALA C CA  1 -0.142 -0.025 0.117  
ATOM   7462  C  C   . ALA C 1 173 ? -14.882 -2.029  45.815  1    109.65 ? 162 ALA C C   1 -0.136 -0.019 0.114  
ATOM   7463  O  O   . ALA C 1 173 ? -14.441 -0.883  45.949  1    110.39 ? 162 ALA C O   1 -0.132 -0.008 0.115  
ATOM   7464  C  CB  . ALA C 1 173 ? -14.527 -3.6    47.729  1    109.57 ? 162 ALA C CB  1 -0.133 -0.033 0.119  
ATOM   7465  N  N   . THR C 1 174 ? -14.791 -2.703  44.661  1    115.6  ? 163 THR C N   1 -0.136 -0.025 0.112  
ATOM   7466  C  CA  . THR C 1 174 ? -14.213 -2.088  43.467  1    112.35 ? 163 THR C CA  1 -0.13  -0.019 0.109  
ATOM   7467  C  C   . THR C 1 174 ? -14.967 -0.819  43.088  1    110.75 ? 163 THR C C   1 -0.137 -0.008 0.108  
ATOM   7468  O  O   . THR C 1 174 ? -14.358 0.217   42.8    1    112.27 ? 163 THR C O   1 -0.132 0.002  0.107  
ATOM   7469  C  CB  . THR C 1 174 ? -14.224 -3.089  42.312  1    110.56 ? 163 THR C CB  1 -0.13  -0.028 0.106  
ATOM   7470  O  OG1 . THR C 1 174 ? -13.775 -4.362  42.782  1    114.04 ? 163 THR C OG1 1 -0.126 -0.04  0.107  
ATOM   7471  C  CG2 . THR C 1 174 ? -13.298 -2.638  41.191  1    113.69 ? 163 THR C CG2 1 -0.122 -0.024 0.103  
ATOM   7472  N  N   . THR C 1 175 ? -16.3   -0.875  43.115  1    109.94 ? 164 THR C N   1 -0.149 -0.008 0.108  
ATOM   7473  C  CA  . THR C 1 175 ? -17.118 0.27    42.74   1    114.03 ? 164 THR C CA  1 -0.157 0.002  0.107  
ATOM   7474  C  C   . THR C 1 175 ? -17.27  1.295   43.866  1    115.43 ? 164 THR C C   1 -0.158 0.012  0.11   
ATOM   7475  O  O   . THR C 1 175 ? -17.682 2.432   43.594  1    117.86 ? 164 THR C O   1 -0.162 0.022  0.109  
ATOM   7476  C  CB  . THR C 1 175 ? -18.493 -0.216  42.273  1    115.21 ? 164 THR C CB  1 -0.169 -0.002 0.106  
ATOM   7477  O  OG1 . THR C 1 175 ? -18.321 -1.387  41.466  1    114.51 ? 164 THR C OG1 1 -0.168 -0.013 0.104  
ATOM   7478  C  CG2 . THR C 1 175 ? -19.186 0.855   41.432  1    111.25 ? 164 THR C CG2 1 -0.176 0.008  0.103  
ATOM   7479  N  N   . LEU C 1 176 ? -16.94  0.937   45.116  1    116.68 ? 165 LEU C N   1 -0.155 0.009  0.113  
ATOM   7480  C  CA  . LEU C 1 176 ? -17.032 1.887   46.226  1    112.98 ? 165 LEU C CA  1 -0.156 0.017  0.115  
ATOM   7481  C  C   . LEU C 1 176 ? -15.709 2.598   46.493  1    110.53 ? 165 LEU C C   1 -0.144 0.024  0.116  
ATOM   7482  O  O   . LEU C 1 176 ? -15.697 3.82    46.68   1    104.37 ? 165 LEU C O   1 -0.144 0.035  0.117  
ATOM   7483  C  CB  . LEU C 1 176 ? -17.516 1.177   47.497  1    107.94 ? 165 LEU C CB  1 -0.161 0.011  0.119  
ATOM   7484  C  CG  . LEU C 1 176 ? -19.039 1.006   47.63   1    107.31 ? 165 LEU C CG  1 -0.174 0.009  0.119  
ATOM   7485  C  CD1 . LEU C 1 176 ? -19.392 -0.054  48.656  1    108.06 ? 165 LEU C CD1 1 -0.178 -0.0   0.121  
ATOM   7486  C  CD2 . LEU C 1 176 ? -19.713 2.319   47.985  1    101.09 ? 165 LEU C CD2 1 -0.181 0.021  0.12   
ATOM   7487  N  N   . PHE C 1 177 ? -14.595 1.855   46.487  1    113.17 ? 166 PHE C N   1 -0.134 0.017  0.116  
ATOM   7488  C  CA  . PHE C 1 177 ? -13.254 2.404   46.689  1    113.74 ? 166 PHE C CA  1 -0.121 0.022  0.117  
ATOM   7489  C  C   . PHE C 1 177 ? -12.776 3.26    45.527  1    122.97 ? 166 PHE C C   1 -0.117 0.03   0.114  
ATOM   7490  O  O   . PHE C 1 177 ? -11.762 3.954   45.673  1    122.31 ? 166 PHE C O   1 -0.108 0.036  0.114  
ATOM   7491  C  CB  . PHE C 1 177 ? -12.209 1.301   46.866  1    116.86 ? 166 PHE C CB  1 -0.112 0.012  0.117  
ATOM   7492  C  CG  . PHE C 1 177 ? -12.365 0.484   48.103  1    115.14 ? 166 PHE C CG  1 -0.113 0.004  0.12   
ATOM   7493  C  CD1 . PHE C 1 177 ? -13.495 0.575   48.887  1    112.25 ? 166 PHE C CD1 1 -0.124 0.005  0.122  
ATOM   7494  C  CD2 . PHE C 1 177 ? -11.352 -0.383  48.482  1    121.63 ? 166 PHE C CD2 1 -0.104 -0.004 0.121  
ATOM   7495  C  CE1 . PHE C 1 177 ? -13.613 -0.181  50.006  1    116.32 ? 166 PHE C CE1 1 -0.125 -0.002 0.125  
ATOM   7496  C  CE2 . PHE C 1 177 ? -11.463 -1.146  49.608  1    122.86 ? 166 PHE C CE2 1 -0.105 -0.011 0.124  
ATOM   7497  C  CZ  . PHE C 1 177 ? -12.593 -1.049  50.373  1    121.75 ? 166 PHE C CZ  1 -0.115 -0.01  0.126  
ATOM   7498  N  N   . ASN C 1 178 ? -13.429 3.175   44.369  1    124.54 ? 167 ASN C N   1 -0.123 0.029  0.111  
ATOM   7499  C  CA  . ASN C 1 178 ? -13.037 3.977   43.22   1    124.57 ? 167 ASN C CA  1 -0.119 0.036  0.108  
ATOM   7500  C  C   . ASN C 1 178 ? -14.08  5.055   42.986  1    131.81 ? 167 ASN C C   1 -0.129 0.046  0.107  
ATOM   7501  O  O   . ASN C 1 178 ? -15.223 4.735   42.612  1    129.77 ? 167 ASN C O   1 -0.14  0.043  0.106  
ATOM   7502  C  CB  . ASN C 1 178 ? -12.87  3.109   41.969  1    122.59 ? 167 ASN C CB  1 -0.118 0.028  0.105  
ATOM   7503  C  CG  . ASN C 1 178 ? -13.147 3.881   40.665  1    128.52 ? 167 ASN C CG  1 -0.12  0.036  0.102  
ATOM   7504  O  OD1 . ASN C 1 178 ? -12.229 4.222   39.916  1    130.15 ? 167 ASN C OD1 1 -0.112 0.039  0.1    
ATOM   7505  N  ND2 . ASN C 1 178 ? -14.425 4.144   40.392  1    120.99 ? 167 ASN C ND2 1 -0.132 0.038  0.101  
ATOM   7506  N  N   . PRO C 1 179 ? -13.746 6.335   43.196  1    139.55 ? 168 PRO C N   1 -0.126 0.058  0.108  
ATOM   7507  C  CA  . PRO C 1 179 ? -14.559 7.418   42.61   1    141.29 ? 168 PRO C CA  1 -0.133 0.068  0.106  
ATOM   7508  C  C   . PRO C 1 179 ? -14.374 7.564   41.099  1    123.73 ? 168 PRO C C   1 -0.132 0.069  0.103  
ATOM   7509  O  O   . PRO C 1 179 ? -13.378 8.145   40.656  1    126    ? 168 PRO C O   1 -0.123 0.075  0.102  
ATOM   7510  C  CB  . PRO C 1 179 ? -14.066 8.672   43.355  1    138.55 ? 168 PRO C CB  1 -0.129 0.079  0.108  
ATOM   7511  C  CG  . PRO C 1 179 ? -12.684 8.301   43.874  1    131.54 ? 168 PRO C CG  1 -0.116 0.076  0.11   
ATOM   7512  C  CD  . PRO C 1 179 ? -12.771 6.832   44.187  1    126.59 ? 168 PRO C CD  1 -0.117 0.063  0.11   
ATOM   7513  N  N   . ALA C 1 180 ? -15.306 7.046   40.298  1    120.92 ? 169 ALA C N   1 -0.14  0.065  0.101  
ATOM   7514  C  CA  . ALA C 1 180 ? -15.362 7.341   38.864  1    117.52 ? 169 ALA C CA  1 -0.141 0.067  0.097  
ATOM   7515  C  C   . ALA C 1 180 ? -16.686 8.029   38.569  1    106.65 ? 169 ALA C C   1 -0.153 0.074  0.096  
ATOM   7516  O  O   . ALA C 1 180 ? -17.754 7.454   38.821  1    100.44 ? 169 ALA C O   1 -0.163 0.068  0.097  
ATOM   7517  C  CB  . ALA C 1 180 ? -15.217 6.084   38.002  1    105.74 ? 169 ALA C CB  1 -0.139 0.056  0.095  
ATOM   7518  N  N   . LYS C 1 181 ? -16.607 9.262   38.048  1    101.67 ? 170 LYS C N   1 -0.152 0.085  0.095  
ATOM   7519  C  CA  . LYS C 1 181 ? -17.811 10.043  37.77   1    105.17 ? 170 LYS C CA  1 -0.163 0.092  0.094  
ATOM   7520  C  C   . LYS C 1 181 ? -18.805 9.236   36.935  1    109.66 ? 170 LYS C C   1 -0.172 0.085  0.092  
ATOM   7521  O  O   . LYS C 1 181 ? -19.959 9.033   37.337  1    107.38 ? 170 LYS C O   1 -0.183 0.083  0.093  
ATOM   7522  C  CB  . LYS C 1 181 ? -17.434 11.346  37.056  1    107.93 ? 170 LYS C CB  1 -0.16  0.104  0.093  
ATOM   7523  C  CG  . LYS C 1 181 ? -16.611 12.337  37.875  1    109.57 ? 170 LYS C CG  1 -0.152 0.113  0.095  
ATOM   7524  C  CD  . LYS C 1 181 ? -17.51  13.104  38.857  1    123.77 ? 170 LYS C CD  1 -0.16  0.12   0.097  
ATOM   7525  C  CE  . LYS C 1 181 ? -18.094 14.396  38.235  1    129.57 ? 170 LYS C CE  1 -0.166 0.132  0.095  
ATOM   7526  N  NZ  . LYS C 1 181 ? -19.407 14.835  38.847  1    121.88 ? 170 LYS C NZ  1 -0.178 0.136  0.097  
ATOM   7527  N  N   . ALA C 1 182 ? -18.357 8.746   35.774  1    108.5  ? 171 ALA C N   1 -0.168 0.08   0.089  
ATOM   7528  C  CA  . ALA C 1 182 ? -19.124 7.817   34.953  1    103.91 ? 171 ALA C CA  1 -0.175 0.072  0.087  
ATOM   7529  C  C   . ALA C 1 182 ? -18.56  6.417   35.163  1    98.83  ? 171 ALA C C   1 -0.17  0.059  0.088  
ATOM   7530  O  O   . ALA C 1 182 ? -17.401 6.151   34.819  1    96.32  ? 171 ALA C O   1 -0.159 0.056  0.087  
ATOM   7531  C  CB  . ALA C 1 182 ? -19.071 8.211   33.477  1    105.42 ? 171 ALA C CB  1 -0.175 0.075  0.084  
ATOM   7532  N  N   . HIS C 1 183 ? -19.376 5.528   35.728  1    98.82  ? 172 HIS C N   1 -0.178 0.051  0.089  
ATOM   7533  C  CA  . HIS C 1 183 ? -18.921 4.212   36.161  1    102.97 ? 172 HIS C CA  1 -0.173 0.039  0.09   
ATOM   7534  C  C   . HIS C 1 183 ? -19.809 3.147   35.537  1    101.65 ? 172 HIS C C   1 -0.182 0.029  0.089  
ATOM   7535  O  O   . HIS C 1 183 ? -21.019 3.104   35.798  1    102.43 ? 172 HIS C O   1 -0.193 0.028  0.089  
ATOM   7536  C  CB  . HIS C 1 183 ? -18.932 4.094   37.695  1    109.06 ? 172 HIS C CB  1 -0.173 0.038  0.094  
ATOM   7537  C  CG  . HIS C 1 183 ? -18.023 3.025   38.217  1    108.14 ? 172 HIS C CG  1 -0.165 0.028  0.095  
ATOM   7538  N  ND1 . HIS C 1 183 ? -16.794 3.302   38.774  1    115.96 ? 172 HIS C ND1 1 -0.154 0.03   0.097  
ATOM   7539  C  CD2 . HIS C 1 183 ? -18.148 1.676   38.235  1    110.12 ? 172 HIS C CD2 1 -0.166 0.015  0.095  
ATOM   7540  C  CE1 . HIS C 1 183 ? -16.208 2.171   39.132  1    117.18 ? 172 HIS C CE1 1 -0.149 0.02   0.098  
ATOM   7541  N  NE2 . HIS C 1 183 ? -17.008 1.17    38.817  1    114.08 ? 172 HIS C NE2 1 -0.156 0.011  0.097  
ATOM   7542  N  N   . PHE C 1 184 ? -19.204 2.285   34.73   1    104.3  ? 173 PHE C N   1 -0.176 0.021  0.087  
ATOM   7543  C  CA  . PHE C 1 184 ? -19.896 1.217   34.016  1    101.92 ? 173 PHE C CA  1 -0.182 0.011  0.085  
ATOM   7544  C  C   . PHE C 1 184 ? -19.332 -0.092  34.553  1    98.32  ? 173 PHE C C   1 -0.177 -0.001 0.086  
ATOM   7545  O  O   . PHE C 1 184 ? -18.143 -0.385  34.366  1    94.98  ? 173 PHE C O   1 -0.166 -0.004 0.086  
ATOM   7546  C  CB  . PHE C 1 184 ? -19.698 1.374   32.503  1    95.39  ? 173 PHE C CB  1 -0.181 0.013  0.081  
ATOM   7547  C  CG  . PHE C 1 184 ? -20.192 2.695   31.981  1    92.39  ? 173 PHE C CG  1 -0.185 0.025  0.08   
ATOM   7548  C  CD1 . PHE C 1 184 ? -19.439 3.855   32.162  1    91.8   ? 173 PHE C CD1 1 -0.178 0.035  0.08   
ATOM   7549  C  CD2 . PHE C 1 184 ? -21.425 2.791   31.352  1    94.05  ? 173 PHE C CD2 1 -0.196 0.026  0.078  
ATOM   7550  C  CE1 . PHE C 1 184 ? -19.902 5.083   31.723  1    88.56  ? 173 PHE C CE1 1 -0.182 0.047  0.079  
ATOM   7551  C  CE2 . PHE C 1 184 ? -21.896 4.017   30.898  1    92.21  ? 173 PHE C CE2 1 -0.201 0.037  0.077  
ATOM   7552  C  CZ  . PHE C 1 184 ? -21.131 5.164   31.087  1    94     ? 173 PHE C CZ  1 -0.194 0.047  0.078  
ATOM   7553  N  N   . SER C 1 185 ? -20.153 -0.851  35.269  1    93.68  ? 174 SER C N   1 -0.185 -0.008 0.088  
ATOM   7554  C  CA  . SER C 1 185 ? -19.676 -2.092  35.859  1    103.9  ? 174 SER C CA  1 -0.18  -0.019 0.09   
ATOM   7555  C  C   . SER C 1 185 ? -20.499 -3.258  35.34   1    98.92  ? 174 SER C C   1 -0.188 -0.03  0.088  
ATOM   7556  O  O   . SER C 1 185 ? -21.733 -3.189  35.274  1    96.72  ? 174 SER C O   1 -0.199 -0.029 0.088  
ATOM   7557  C  CB  . SER C 1 185 ? -19.703 -2.058  37.402  1    104.05 ? 174 SER C CB  1 -0.181 -0.019 0.093  
ATOM   7558  O  OG  . SER C 1 185 ? -21.03  -2.035  37.895  1    111.42 ? 174 SER C OG  1 -0.193 -0.019 0.095  
ATOM   7559  N  N   . PHE C 1 186 ? -19.788 -4.326  34.99   1    96.85  ? 175 PHE C N   1 -0.181 -0.04  0.087  
ATOM   7560  C  CA  . PHE C 1 186 ? -20.338 -5.527  34.377  1    98.85  ? 175 PHE C CA  1 -0.186 -0.051 0.086  
ATOM   7561  C  C   . PHE C 1 186 ? -20.171 -6.668  35.376  1    96.66  ? 175 PHE C C   1 -0.185 -0.061 0.088  
ATOM   7562  O  O   . PHE C 1 186 ? -19.146 -7.35   35.398  1    94.86  ? 175 PHE C O   1 -0.175 -0.067 0.088  
ATOM   7563  C  CB  . PHE C 1 186 ? -19.626 -5.813  33.058  1    97.85  ? 175 PHE C CB  1 -0.18  -0.053 0.083  
ATOM   7564  C  CG  . PHE C 1 186 ? -19.877 -4.771  32.016  1    95.25  ? 175 PHE C CG  1 -0.182 -0.044 0.08   
ATOM   7565  C  CD1 . PHE C 1 186 ? -19.165 -3.589  32.011  1    93.76  ? 175 PHE C CD1 1 -0.176 -0.033 0.08   
ATOM   7566  C  CD2 . PHE C 1 186 ? -20.863 -4.964  31.062  1    97.03  ? 175 PHE C CD2 1 -0.191 -0.045 0.078  
ATOM   7567  C  CE1 . PHE C 1 186 ? -19.433 -2.622  31.063  1    100.95 ? 175 PHE C CE1 1 -0.178 -0.024 0.078  
ATOM   7568  C  CE2 . PHE C 1 186 ? -21.129 -4.023  30.115  1    97.98  ? 175 PHE C CE2 1 -0.194 -0.037 0.075  
ATOM   7569  C  CZ  . PHE C 1 186 ? -20.416 -2.846  30.105  1    105.48 ? 175 PHE C CZ  1 -0.187 -0.026 0.075  
ATOM   7570  N  N   . GLY C 1 187 ? -21.183 -6.86   36.213  1    86.56  ? 176 GLY C N   1 -0.194 -0.063 0.09   
ATOM   7571  C  CA  . GLY C 1 187 ? -21.172 -8      37.104  1    92.88  ? 176 GLY C CA  1 -0.194 -0.073 0.093  
ATOM   7572  C  C   . GLY C 1 187 ? -22.507 -8.717  37.143  1    98.53  ? 176 GLY C C   1 -0.206 -0.08  0.093  
ATOM   7573  O  O   . GLY C 1 187 ? -23.279 -8.652  36.175  1    98.01  ? 176 GLY C O   1 -0.213 -0.079 0.09   
ATOM   7574  N  N   . LEU C 1 188 ? -22.792 -9.392  38.263  1    93.24  ? 177 LEU C N   1 -0.209 -0.086 0.096  
ATOM   7575  C  CA  . LEU C 1 188 ? -24.032 -10.134 38.393  1    83.59  ? 177 LEU C CA  1 -0.22  -0.093 0.096  
ATOM   7576  C  C   . LEU C 1 188 ? -25.149 -9.164  38.748  1    81.44  ? 177 LEU C C   1 -0.23  -0.084 0.097  
ATOM   7577  O  O   . LEU C 1 188 ? -24.881 -8.034  39.145  1    81.72  ? 177 LEU C O   1 -0.228 -0.074 0.098  
ATOM   7578  C  CB  . LEU C 1 188 ? -23.858 -11.224 39.434  1    94.82  ? 177 LEU C CB  1 -0.219 -0.103 0.098  
ATOM   7579  C  CG  . LEU C 1 188 ? -22.508 -11.935 39.276  1    105.74 ? 177 LEU C CG  1 -0.206 -0.109 0.098  
ATOM   7580  C  CD1 . LEU C 1 188 ? -21.448 -11.311 40.207  1    103.85 ? 177 LEU C CD1 1 -0.197 -0.104 0.1    
ATOM   7581  C  CD2 . LEU C 1 188 ? -22.613 -13.455 39.477  1    108.91 ? 177 LEU C CD2 1 -0.207 -0.123 0.099  
ATOM   7582  N  N   . PRO C 1 189 ? -26.402 -9.533  38.54   1    79.79  ? 178 PRO C N   1 -0.242 -0.087 0.096  
ATOM   7583  C  CA  . PRO C 1 189 ? -27.469 -8.528  38.566  1    87.67  ? 178 PRO C CA  1 -0.252 -0.078 0.096  
ATOM   7584  C  C   . PRO C 1 189 ? -27.871 -8.218  40.007  1    99.44  ? 178 PRO C C   1 -0.255 -0.075 0.1    
ATOM   7585  O  O   . PRO C 1 189 ? -27.288 -8.726  40.961  1    104.43 ? 178 PRO C O   1 -0.25  -0.08  0.102  
ATOM   7586  C  CB  . PRO C 1 189 ? -28.588 -9.183  37.755  1    90.43  ? 178 PRO C CB  1 -0.262 -0.084 0.094  
ATOM   7587  C  CG  . PRO C 1 189 ? -28.385 -10.641 37.953  1    89.18  ? 178 PRO C CG  1 -0.26  -0.098 0.095  
ATOM   7588  C  CD  . PRO C 1 189 ? -26.905 -10.874 38.187  1    77.27  ? 178 PRO C CD  1 -0.247 -0.1   0.095  
ATOM   7589  N  N   . SER C 1 190 ? -28.873 -7.346  40.16   1    103.05 ? 179 SER C N   1 -0.265 -0.067 0.1    
ATOM   7590  C  CA  . SER C 1 190 ? -29.171 -6.785  41.473  1    97.42  ? 179 SER C CA  1 -0.267 -0.062 0.104  
ATOM   7591  C  C   . SER C 1 190 ? -30.622 -6.344  41.627  1    100.71 ? 179 SER C C   1 -0.281 -0.058 0.104  
ATOM   7592  O  O   . SER C 1 190 ? -31.24  -6.593  42.664  1    107.14 ? 179 SER C O   1 -0.286 -0.06  0.107  
ATOM   7593  C  CB  . SER C 1 190 ? -28.257 -5.594  41.745  1    99.21  ? 179 SER C CB  1 -0.259 -0.051 0.104  
ATOM   7594  O  OG  . SER C 1 190 ? -28.766 -4.448  41.083  1    105.56 ? 179 SER C OG  1 -0.264 -0.041 0.103  
ATOM   7595  N  N   . HIS C 1 191 ? -31.183 -5.696  40.61   1    103.68 ? 180 HIS C N   1 -0.286 -0.052 0.101  
ATOM   7596  C  CA  . HIS C 1 191 ? -32.45  -4.981  40.754  1    104.04 ? 180 HIS C CA  1 -0.297 -0.046 0.102  
ATOM   7597  C  C   . HIS C 1 191 ? -33.611 -5.875  41.196  1    105.17 ? 180 HIS C C   1 -0.308 -0.054 0.103  
ATOM   7598  O  O   . HIS C 1 191 ? -34.728 -5.391  41.41   1    104.5  ? 180 HIS C O   1 -0.318 -0.049 0.103  
ATOM   7599  C  CB  . HIS C 1 191 ? -32.794 -4.248  39.441  1    112.61 ? 180 HIS C CB  1 -0.301 -0.039 0.098  
ATOM   7600  C  CG  . HIS C 1 191 ? -33.306 -5.13   38.339  1    109.23 ? 180 HIS C CG  1 -0.305 -0.047 0.096  
ATOM   7601  N  ND1 . HIS C 1 191 ? -34.36  -4.765  37.526  1    105.97 ? 180 HIS C ND1 1 -0.315 -0.044 0.094  
ATOM   7602  C  CD2 . HIS C 1 191 ? -32.91  -6.355  37.915  1    108.02 ? 180 HIS C CD2 1 -0.302 -0.058 0.095  
ATOM   7603  C  CE1 . HIS C 1 191 ? -34.591 -5.73   36.649  1    111.31 ? 180 HIS C CE1 1 -0.317 -0.053 0.092  
ATOM   7604  N  NE2 . HIS C 1 191 ? -33.724 -6.706  36.86   1    106.82 ? 180 HIS C NE2 1 -0.309 -0.061 0.092  
ATOM   7605  N  N   . HIS C 1 192 ? -33.359 -7.173  41.358  1    105.59 ? 181 HIS C N   1 -0.306 -0.066 0.103  
ATOM   7606  C  CA  . HIS C 1 192 ? -34.331 -8.071  41.969  1    111.67 ? 181 HIS C CA  1 -0.315 -0.074 0.105  
ATOM   7607  C  C   . HIS C 1 192 ? -34.064 -8.352  43.452  1    112.02 ? 181 HIS C C   1 -0.312 -0.077 0.108  
ATOM   7608  O  O   . HIS C 1 192 ? -35.012 -8.625  44.196  1    113.06 ? 181 HIS C O   1 -0.321 -0.079 0.11   
ATOM   7609  C  CB  . HIS C 1 192 ? -34.377 -9.392  41.194  1    107.52 ? 181 HIS C CB  1 -0.315 -0.086 0.103  
ATOM   7610  C  CG  . HIS C 1 192 ? -35.137 -9.319  39.906  1    114.09 ? 181 HIS C CG  1 -0.322 -0.085 0.1    
ATOM   7611  N  ND1 . HIS C 1 192 ? -36.146 -8.403  39.683  1    117.03 ? 181 HIS C ND1 1 -0.331 -0.077 0.099  
ATOM   7612  C  CD2 . HIS C 1 192 ? -35.041 -10.055 38.769  1    114.32 ? 181 HIS C CD2 1 -0.321 -0.092 0.097  
ATOM   7613  C  CE1 . HIS C 1 192 ? -36.637 -8.577  38.465  1    112.69 ? 181 HIS C CE1 1 -0.336 -0.079 0.096  
ATOM   7614  N  NE2 . HIS C 1 192 ? -35.984 -9.573  37.889  1    111.49 ? 181 HIS C NE2 1 -0.33  -0.088 0.095  
ATOM   7615  N  N   . ALA C 1 193 ? -32.813 -8.279  43.907  1    108.94 ? 182 ALA C N   1 -0.301 -0.076 0.11   
ATOM   7616  C  CA  . ALA C 1 193 ? -32.492 -8.57   45.301  1    109.87 ? 182 ALA C CA  1 -0.298 -0.079 0.113  
ATOM   7617  C  C   . ALA C 1 193 ? -33.223 -7.633  46.264  1    114.37 ? 182 ALA C C   1 -0.304 -0.07  0.116  
ATOM   7618  O  O   . ALA C 1 193 ? -33.141 -6.406  46.139  1    111.19 ? 182 ALA C O   1 -0.304 -0.059 0.115  
ATOM   7619  C  CB  . ALA C 1 193 ? -30.983 -8.469  45.515  1    104.81 ? 182 ALA C CB  1 -0.284 -0.078 0.114  
ATOM   7620  N  N   . TYR C 1 194 ? -33.936 -8.226  47.228  1    118.16 ? 183 TYR C N   1 -0.311 -0.075 0.118  
ATOM   7621  C  CA  . TYR C 1 194 ? -34.595 -7.525  48.322  1    112.27 ? 183 TYR C CA  1 -0.317 -0.069 0.121  
ATOM   7622  C  C   . TYR C 1 194 ? -33.677 -7.415  49.549  1    117.52 ? 183 TYR C C   1 -0.309 -0.068 0.124  
ATOM   7623  O  O   . TYR C 1 194 ? -32.687 -8.142  49.677  1    117.97 ? 183 TYR C O   1 -0.3   -0.075 0.124  
ATOM   7624  C  CB  . TYR C 1 194 ? -35.878 -8.256  48.715  1    111.49 ? 183 TYR C CB  1 -0.329 -0.076 0.122  
ATOM   7625  C  CG  . TYR C 1 194 ? -37.048 -8.115  47.769  1    113.71 ? 183 TYR C CG  1 -0.34  -0.074 0.119  
ATOM   7626  C  CD1 . TYR C 1 194 ? -37.847 -6.976  47.793  1    113.79 ? 183 TYR C CD1 1 -0.347 -0.064 0.119  
ATOM   7627  C  CD2 . TYR C 1 194 ? -37.39  -9.138  46.887  1    115.59 ? 183 TYR C CD2 1 -0.343 -0.084 0.117  
ATOM   7628  C  CE1 . TYR C 1 194 ? -38.931 -6.843  46.952  1    111.79 ? 183 TYR C CE1 1 -0.357 -0.063 0.117  
ATOM   7629  C  CE2 . TYR C 1 194 ? -38.481 -9.01   46.038  1    110.56 ? 183 TYR C CE2 1 -0.353 -0.083 0.115  
ATOM   7630  C  CZ  . TYR C 1 194 ? -39.242 -7.857  46.081  1    111.14 ? 183 TYR C CZ  1 -0.36  -0.072 0.115  
ATOM   7631  O  OH  . TYR C 1 194 ? -40.326 -7.707  45.261  1    114.25 ? 183 TYR C OH  1 -0.37  -0.071 0.113  
ATOM   7632  N  N   . THR C 1 195 ? -34.033 -6.491  50.463  1    119.66 ? 184 THR C N   1 -0.312 -0.059 0.126  
ATOM   7633  C  CA  . THR C 1 195 ? -33.365 -6.414  51.765  1    118.06 ? 184 THR C CA  1 -0.306 -0.059 0.129  
ATOM   7634  C  C   . THR C 1 195 ? -33.306 -7.756  52.449  1    120.3  ? 184 THR C C   1 -0.305 -0.071 0.131  
ATOM   7635  O  O   . THR C 1 195 ? -32.266 -8.143  52.994  1    121.16 ? 184 THR C O   1 -0.296 -0.075 0.132  
ATOM   7636  C  CB  . THR C 1 195 ? -34.061 -5.444  52.702  1    111.8  ? 184 THR C CB  1 -0.312 -0.05  0.132  
ATOM   7637  O  OG1 . THR C 1 195 ? -33.671 -4.145  52.312  1    106.61 ? 184 THR C OG1 1 -0.309 -0.038 0.131  
ATOM   7638  C  CG2 . THR C 1 195 ? -33.465 -5.559  54.056  1    118.84 ? 184 THR C CG2 1 -0.307 -0.051 0.135  
ATOM   7639  N  N   . GLN C 1 196 ? -34.417 -8.475  52.445  1    119.53 ? 185 GLN C N   1 -0.315 -0.078 0.131  
ATOM   7640  C  CA  . GLN C 1 196 ? -34.543 -9.677  53.235  1    124.27 ? 185 GLN C CA  1 -0.317 -0.089 0.133  
ATOM   7641  C  C   . GLN C 1 196 ? -34.674 -10.955 52.413  1    125.48 ? 185 GLN C C   1 -0.318 -0.1   0.131  
ATOM   7642  O  O   . GLN C 1 196 ? -34.518 -12.036 52.982  1    124.55 ? 185 GLN C O   1 -0.316 -0.11  0.132  
ATOM   7643  C  CB  . GLN C 1 196 ? -35.74  -9.524  54.193  1    135.5  ? 185 GLN C CB  1 -0.328 -0.087 0.135  
ATOM   7644  C  CG  . GLN C 1 196 ? -37.07  -9.029  53.535  1    141.16 ? 185 GLN C CG  1 -0.34  -0.083 0.134  
ATOM   7645  C  CD  . GLN C 1 196 ? -37.111 -7.53   53.176  1    136.35 ? 185 GLN C CD  1 -0.34  -0.069 0.133  
ATOM   7646  O  OE1 . GLN C 1 196 ? -36.626 -7.118  52.099  1    125.01 ? 185 GLN C OE1 1 -0.336 -0.065 0.13   
ATOM   7647  N  NE2 . GLN C 1 196 ? -37.748 -6.724  54.041  1    128.74 ? 185 GLN C NE2 1 -0.346 -0.062 0.135  
ATOM   7648  N  N   . MET C 1 197 ? -34.916 -10.867 51.098  1    131.51 ? 186 MET C N   1 -0.32  -0.1   0.128  
ATOM   7649  C  CA  . MET C 1 197 ? -35.072 -12.026 50.217  1    129.73 ? 186 MET C CA  1 -0.321 -0.11  0.125  
ATOM   7650  C  C   . MET C 1 197 ? -34.23  -11.824 48.958  1    125.11 ? 186 MET C C   1 -0.314 -0.108 0.122  
ATOM   7651  O  O   . MET C 1 197 ? -34.06  -10.698 48.481  1    118.55 ? 186 MET C O   1 -0.312 -0.098 0.121  
ATOM   7652  C  CB  . MET C 1 197 ? -36.569 -12.253 49.82   1    133.82 ? 186 MET C CB  1 -0.335 -0.112 0.124  
ATOM   7653  C  CG  . MET C 1 197 ? -37.576 -12.31  51.003  1    137.84 ? 186 MET C CG  1 -0.344 -0.113 0.127  
ATOM   7654  S  SD  . MET C 1 197 ? -39.163 -11.491 50.646  1    154.93 ? 186 MET C SD  1 -0.359 -0.105 0.126  
ATOM   7655  C  CE  . MET C 1 197 ? -40.327 -12.431 51.641  1    132.19 ? 186 MET C CE  1 -0.37  -0.114 0.129  
ATOM   7656  N  N   . GLY C 1 198 ? -33.692 -12.915 48.419  1    126.42 ? 187 GLY C N   1 -0.309 -0.118 0.121  
ATOM   7657  C  CA  . GLY C 1 198 ? -32.984 -12.827 47.148  1    119.82 ? 187 GLY C CA  1 -0.302 -0.118 0.118  
ATOM   7658  C  C   . GLY C 1 198 ? -33.767 -13.423 45.988  1    118.57 ? 187 GLY C C   1 -0.309 -0.123 0.115  
ATOM   7659  O  O   . GLY C 1 198 ? -34.036 -14.631 45.96   1    116.46 ? 187 GLY C O   1 -0.312 -0.134 0.115  
ATOM   7660  N  N   . SER C 1 199 ? -34.149 -12.602 45.016  1    116.9  ? 188 SER C N   1 -0.313 -0.115 0.112  
ATOM   7661  C  CA  . SER C 1 199 ? -35.074 -13.053 43.99   1    116.78 ? 188 SER C CA  1 -0.321 -0.12  0.11   
ATOM   7662  C  C   . SER C 1 199 ? -34.458 -12.94  42.599  1    119.26 ? 188 SER C C   1 -0.316 -0.119 0.106  
ATOM   7663  O  O   . SER C 1 199 ? -33.595 -12.089 42.342  1    112.78 ? 188 SER C O   1 -0.308 -0.111 0.106  
ATOM   7664  C  CB  . SER C 1 199 ? -36.393 -12.266 44.046  1    116.7  ? 188 SER C CB  1 -0.334 -0.112 0.11   
ATOM   7665  O  OG  . SER C 1 199 ? -36.24  -10.953 43.53   1    120.54 ? 188 SER C OG  1 -0.332 -0.1   0.109  
ATOM   7666  N  N   . GLY C 1 200 ? -34.918 -13.835 41.717  1    114.62 ? 189 GLY C N   1 -0.32  -0.127 0.104  
ATOM   7667  C  CA  . GLY C 1 200 ? -34.54  -13.919 40.323  1    109.85 ? 189 GLY C CA  1 -0.317 -0.128 0.101  
ATOM   7668  C  C   . GLY C 1 200 ? -33.134 -13.51  39.944  1    109.79 ? 189 GLY C C   1 -0.304 -0.124 0.1    
ATOM   7669  O  O   . GLY C 1 200 ? -32.911 -12.366 39.538  1    114.31 ? 189 GLY C O   1 -0.302 -0.113 0.099  
ATOM   7670  N  N   . PHE C 1 201 ? -32.185 -14.438 40.054  1    105.51 ? 190 PHE C N   1 -0.295 -0.132 0.1    
ATOM   7671  C  CA  . PHE C 1 201 ? -30.852 -14.277 39.475  1    104.86 ? 190 PHE C CA  1 -0.283 -0.131 0.099  
ATOM   7672  C  C   . PHE C 1 201 ? -29.988 -13.273 40.23   1    101.92 ? 190 PHE C C   1 -0.275 -0.122 0.1    
ATOM   7673  O  O   . PHE C 1 201 ? -28.77  -13.252 40.033  1    97.42  ? 190 PHE C O   1 -0.264 -0.121 0.1    
ATOM   7674  C  CB  . PHE C 1 201 ? -30.931 -13.845 38.003  1    121.49 ? 190 PHE C CB  1 -0.283 -0.127 0.095  
ATOM   7675  C  CG  . PHE C 1 201 ? -31.69  -14.795 37.101  1    119.84 ? 190 PHE C CG  1 -0.29  -0.136 0.093  
ATOM   7676  C  CD1 . PHE C 1 201 ? -33.017 -15.129 37.335  1    126.17 ? 190 PHE C CD1 1 -0.303 -0.139 0.093  
ATOM   7677  C  CD2 . PHE C 1 201 ? -31.095 -15.302 35.991  1    114.25 ? 190 PHE C CD2 1 -0.285 -0.14  0.09   
ATOM   7678  C  CE1 . PHE C 1 201 ? -33.709 -15.977 36.504  1    125.17 ? 190 PHE C CE1 1 -0.309 -0.146 0.091  
ATOM   7679  C  CE2 . PHE C 1 201 ? -31.795 -16.142 35.172  1    123.8  ? 190 PHE C CE2 1 -0.291 -0.148 0.088  
ATOM   7680  C  CZ  . PHE C 1 201 ? -33.099 -16.478 35.419  1    124.84 ? 190 PHE C CZ  1 -0.303 -0.151 0.088  
ATOM   7681  N  N   . CYS C 1 202 ? -30.596 -12.457 41.097  1    108.49 ? 191 CYS C N   1 -0.28  -0.114 0.103  
ATOM   7682  C  CA  . CYS C 1 202 ? -29.916 -11.416 41.868  1    108.85 ? 191 CYS C CA  1 -0.274 -0.105 0.105  
ATOM   7683  C  C   . CYS C 1 202 ? -29.75  -11.817 43.332  1    111.8  ? 191 CYS C C   1 -0.273 -0.108 0.108  
ATOM   7684  O  O   . CYS C 1 202 ? -30.664 -12.388 43.941  1    114.48 ? 191 CYS C O   1 -0.281 -0.114 0.11   
ATOM   7685  C  CB  . CYS C 1 202 ? -30.69  -10.099 41.808  1    110.37 ? 191 CYS C CB  1 -0.281 -0.093 0.104  
ATOM   7686  S  SG  . CYS C 1 202 ? -30.971 -9.494  40.123  1    106.84 ? 191 CYS C SG  1 -0.284 -0.087 0.1    
ATOM   7687  N  N   . LEU C 1 203 ? -28.591 -11.482 43.902  1    108.35 ? 192 LEU C N   1 -0.262 -0.105 0.11   
ATOM   7688  C  CA  . LEU C 1 203 ? -28.233 -11.845 45.268  1    102.59 ? 192 LEU C CA  1 -0.259 -0.109 0.113  
ATOM   7689  C  C   . LEU C 1 203 ? -28.22  -10.659 46.22   1    106.44 ? 192 LEU C C   1 -0.259 -0.098 0.115  
ATOM   7690  O  O   . LEU C 1 203 ? -28.881 -10.704 47.26   1    115.18 ? 192 LEU C O   1 -0.265 -0.098 0.118  
ATOM   7691  C  CB  . LEU C 1 203 ? -26.867 -12.535 45.282  1    97.24  ? 192 LEU C CB  1 -0.246 -0.115 0.113  
ATOM   7692  C  CG  . LEU C 1 203 ? -26.911 -13.953 44.732  1    93.34  ? 192 LEU C CG  1 -0.247 -0.128 0.112  
ATOM   7693  C  CD1 . LEU C 1 203 ? -25.563 -14.621 44.88   1    83.01  ? 192 LEU C CD1 1 -0.234 -0.134 0.112  
ATOM   7694  C  CD2 . LEU C 1 203 ? -27.986 -14.733 45.449  1    97.78  ? 192 LEU C CD2 1 -0.256 -0.135 0.113  
ATOM   7695  N  N   . ILE C 1 204 ? -27.47  -9.603  45.914  1    102.06 ? 193 ILE C N   1 -0.252 -0.088 0.115  
ATOM   7696  C  CA  . ILE C 1 204 ? -27.505 -8.371  46.69   1    103.78 ? 193 ILE C CA  1 -0.252 -0.077 0.117  
ATOM   7697  C  C   . ILE C 1 204 ? -27.795 -7.208  45.753  1    107.67 ? 193 ILE C C   1 -0.255 -0.066 0.114  
ATOM   7698  O  O   . ILE C 1 204 ? -27.333 -7.187  44.607  1    112.23 ? 193 ILE C O   1 -0.25  -0.066 0.111  
ATOM   7699  C  CB  . ILE C 1 204 ? -26.195 -8.136  47.467  1    106.87 ? 193 ILE C CB  1 -0.24  -0.075 0.119  
ATOM   7700  C  CG1 . ILE C 1 204 ? -25.018 -8.042  46.519  1    94.76  ? 193 ILE C CG1 1 -0.229 -0.074 0.116  
ATOM   7701  C  CG2 . ILE C 1 204 ? -25.966 -9.249  48.492  1    108.28 ? 193 ILE C CG2 1 -0.238 -0.085 0.121  
ATOM   7702  C  CD1 . ILE C 1 204 ? -23.672 -8.074  47.199  1    97.93  ? 193 ILE C CD1 1 -0.217 -0.074 0.118  
ATOM   7703  N  N   . ASN C 1 205 ? -28.589 -6.252  46.231  1    111.15 ? 194 ASN C N   1 -0.262 -0.057 0.115  
ATOM   7704  C  CA  . ASN C 1 205 ? -28.973 -5.095  45.426  1    105.89 ? 194 ASN C CA  1 -0.266 -0.047 0.113  
ATOM   7705  C  C   . ASN C 1 205 ? -27.873 -4.055  45.55   1    108.12 ? 194 ASN C C   1 -0.255 -0.037 0.114  
ATOM   7706  O  O   . ASN C 1 205 ? -27.825 -3.286  46.518  1    106.2  ? 194 ASN C O   1 -0.255 -0.03  0.116  
ATOM   7707  C  CB  . ASN C 1 205 ? -30.316 -4.547  45.874  1    107.24 ? 194 ASN C CB  1 -0.278 -0.042 0.115  
ATOM   7708  C  CG  . ASN C 1 205 ? -30.837 -3.481  44.95   1    107.18 ? 194 ASN C CG  1 -0.283 -0.032 0.112  
ATOM   7709  O  OD1 . ASN C 1 205 ? -30.127 -2.532  44.617  1    108.89 ? 194 ASN C OD1 1 -0.276 -0.023 0.111  
ATOM   7710  N  ND2 . ASN C 1 205 ? -32.084 -3.63   44.522  1    105.37 ? 194 ASN C ND2 1 -0.294 -0.033 0.111  
ATOM   7711  N  N   . LYS C 1 206 ? -27     -4.028  44.54   1    109.77 ? 195 LYS C N   1 -0.247 -0.037 0.111  
ATOM   7712  C  CA  . LYS C 1 206 ? -25.756 -3.273  44.609  1    104.1  ? 195 LYS C CA  1 -0.236 -0.03  0.111  
ATOM   7713  C  C   . LYS C 1 206 ? -25.984 -1.778  44.418  1    101.37 ? 195 LYS C C   1 -0.238 -0.016 0.111  
ATOM   7714  O  O   . LYS C 1 206 ? -25.341 -0.955  45.082  1    97.31  ? 195 LYS C O   1 -0.232 -0.009 0.113  
ATOM   7715  C  CB  . LYS C 1 206 ? -24.781 -3.809  43.568  1    93.1   ? 195 LYS C CB  1 -0.227 -0.035 0.109  
ATOM   7716  C  CG  . LYS C 1 206 ? -23.447 -3.092  43.592  1    91.78  ? 195 LYS C CG  1 -0.215 -0.028 0.109  
ATOM   7717  C  CD  . LYS C 1 206 ? -23.027 -2.872  42.147  1    106.27 ? 195 LYS C CD  1 -0.211 -0.026 0.105  
ATOM   7718  C  CE  . LYS C 1 206 ? -21.659 -2.188  41.855  1    108.04 ? 195 LYS C CE  1 -0.198 -0.02  0.105  
ATOM   7719  N  NZ  . LYS C 1 206 ? -21.301 -2.226  40.381  1    104.07 ? 195 LYS C NZ  1 -0.195 -0.02  0.101  
ATOM   7720  N  N   . THR C 1 207 ? -26.887 -1.403  43.515  1    109.71 ? 196 THR C N   1 -0.246 -0.013 0.109  
ATOM   7721  C  CA  . THR C 1 207 ? -27.135 0.018   43.3    1    110.5  ? 196 THR C CA  1 -0.249 0.0    0.108  
ATOM   7722  C  C   . THR C 1 207 ? -27.768 0.665   44.531  1    105.26 ? 196 THR C C   1 -0.254 0.006  0.111  
ATOM   7723  O  O   . THR C 1 207 ? -27.526 1.848   44.801  1    105.5  ? 196 THR C O   1 -0.252 0.017  0.112  
ATOM   7724  C  CB  . THR C 1 207 ? -27.998 0.206   42.052  1    99.44  ? 196 THR C CB  1 -0.257 0.002  0.105  
ATOM   7725  O  OG1 . THR C 1 207 ? -29.1   1.069   42.358  1    108.23 ? 196 THR C OG1 1 -0.267 0.01   0.106  
ATOM   7726  C  CG2 . THR C 1 207 ? -28.516 -1.146  41.551  1    93.08  ? 196 THR C CG2 1 -0.261 -0.011 0.104  
ATOM   7727  N  N   . ALA C 1 208 ? -28.546 -0.098  45.304  1    105.23 ? 197 ALA C N   1 -0.262 -0.001 0.113  
ATOM   7728  C  CA  . ALA C 1 208 ? -29.097 0.429   46.555  1    109.94 ? 197 ALA C CA  1 -0.267 0.004  0.116  
ATOM   7729  C  C   . ALA C 1 208 ? -27.991 0.748   47.563  1    105.25 ? 197 ALA C C   1 -0.257 0.007  0.119  
ATOM   7730  O  O   . ALA C 1 208 ? -28.06  1.755   48.275  1    109.45 ? 197 ALA C O   1 -0.257 0.016  0.121  
ATOM   7731  C  CB  . ALA C 1 208 ? -30.102 -0.564  47.143  1    109.28 ? 197 ALA C CB  1 -0.276 -0.005 0.118  
ATOM   7732  N  N   . MET C 1 209 ? -26.965 -0.098  47.641  1    99.87  ? 198 MET C N   1 -0.247 -0.001 0.119  
ATOM   7733  C  CA  . MET C 1 209 ? -25.777 0.254   48.412  1    99.62  ? 198 MET C CA  1 -0.236 0.002  0.121  
ATOM   7734  C  C   . MET C 1 209 ? -25.109 1.511   47.866  1    107.25 ? 198 MET C C   1 -0.23  0.014  0.12   
ATOM   7735  O  O   . MET C 1 209 ? -24.876 2.471   48.609  1    111.38 ? 198 MET C O   1 -0.228 0.023  0.121  
ATOM   7736  C  CB  . MET C 1 209 ? -24.797 -0.912  48.411  1    94.66  ? 198 MET C CB  1 -0.227 -0.008 0.121  
ATOM   7737  C  CG  . MET C 1 209 ? -25.461 -2.227  48.699  1    95.63  ? 198 MET C CG  1 -0.233 -0.02  0.122  
ATOM   7738  S  SD  . MET C 1 209 ? -24.246 -3.552  48.768  1    108.38 ? 198 MET C SD  1 -0.222 -0.033 0.122  
ATOM   7739  C  CE  . MET C 1 209 ? -22.785 -2.68   49.324  1    93.97  ? 198 MET C CE  1 -0.209 -0.025 0.123  
ATOM   7740  N  N   . LEU C 1 210 ? -24.798 1.525   46.559  1    109.9  ? 199 LEU C N   1 -0.227 0.014  0.116  
ATOM   7741  C  CA  . LEU C 1 210 ? -24.12  2.676   45.954  1    109.68 ? 199 LEU C CA  1 -0.221 0.025  0.115  
ATOM   7742  C  C   . LEU C 1 210 ? -24.894 3.973   46.171  1    109.57 ? 199 LEU C C   1 -0.228 0.036  0.115  
ATOM   7743  O  O   . LEU C 1 210 ? -24.282 5.039   46.318  1    109.64 ? 199 LEU C O   1 -0.223 0.046  0.116  
ATOM   7744  C  CB  . LEU C 1 210 ? -23.885 2.435   44.458  1    106.65 ? 199 LEU C CB  1 -0.219 0.022  0.111  
ATOM   7745  C  CG  . LEU C 1 210 ? -22.479 1.984   44.026  1    103.19 ? 199 LEU C CG  1 -0.206 0.018  0.11   
ATOM   7746  C  CD1 . LEU C 1 210 ? -21.4   2.995   44.5    1    95.9   ? 199 LEU C CD1 1 -0.196 0.027  0.111  
ATOM   7747  C  CD2 . LEU C 1 210 ? -22.171 0.533   44.469  1    100.42 ? 199 LEU C CD2 1 -0.203 0.005  0.111  
ATOM   7748  N  N   . MET C 1 211 ? -26.227 3.907   46.223  1    107.53 ? 200 MET C N   1 -0.24  0.036  0.115  
ATOM   7749  C  CA  . MET C 1 211 ? -27.006 5.082   46.601  1    111.3  ? 200 MET C CA  1 -0.247 0.047  0.116  
ATOM   7750  C  C   . MET C 1 211 ? -26.876 5.384   48.096  1    117.51 ? 200 MET C C   1 -0.246 0.049  0.12   
ATOM   7751  O  O   . MET C 1 211 ? -26.717 6.546   48.489  1    117.62 ? 200 MET C O   1 -0.245 0.06   0.121  
ATOM   7752  C  CB  . MET C 1 211 ? -28.471 4.885   46.223  1    111.38 ? 200 MET C CB  1 -0.261 0.045  0.115  
ATOM   7753  C  CG  . MET C 1 211 ? -28.734 4.866   44.739  1    110.66 ? 200 MET C CG  1 -0.263 0.045  0.112  
ATOM   7754  S  SD  . MET C 1 211 ? -30.421 4.319   44.428  1    122.79 ? 200 MET C SD  1 -0.279 0.04   0.111  
ATOM   7755  C  CE  . MET C 1 211 ? -31.241 4.985   45.87   1    115.22 ? 200 MET C CE  1 -0.286 0.046  0.115  
ATOM   7756  N  N   . LYS C 1 212 ? -26.958 4.354   48.949  1    111.36 ? 201 LYS C N   1 -0.247 0.04   0.122  
ATOM   7757  C  CA  . LYS C 1 212 ? -26.789 4.587   50.382  1    118.28 ? 201 LYS C CA  1 -0.245 0.042  0.126  
ATOM   7758  C  C   . LYS C 1 212 ? -25.479 5.319   50.658  1    118.46 ? 201 LYS C C   1 -0.233 0.049  0.126  
ATOM   7759  O  O   . LYS C 1 212 ? -25.452 6.279   51.441  1    119.23 ? 201 LYS C O   1 -0.233 0.058  0.128  
ATOM   7760  C  CB  . LYS C 1 212 ? -26.869 3.263   51.159  1    120.34 ? 201 LYS C CB  1 -0.246 0.03   0.128  
ATOM   7761  C  CG  . LYS C 1 212 ? -26.114 3.193   52.521  1    115.66 ? 201 LYS C CG  1 -0.239 0.029  0.131  
ATOM   7762  C  CD  . LYS C 1 212 ? -26.49  4.267   53.553  1    114.98 ? 201 LYS C CD  1 -0.243 0.039  0.134  
ATOM   7763  C  CE  . LYS C 1 212 ? -27.989 4.417   53.766  1    123.2  ? 201 LYS C CE  1 -0.256 0.04   0.134  
ATOM   7764  N  NZ  . LYS C 1 212 ? -28.265 5.378   54.887  1    123.53 ? 201 LYS C NZ  1 -0.259 0.049  0.137  
ATOM   7765  N  N   . GLN C 1 213 ? -24.392 4.905   50.004  1    113.37 ? 202 GLN C N   1 -0.224 0.045  0.125  
ATOM   7766  C  CA  . GLN C 1 213 ? -23.156 5.661   50.113  1    114.42 ? 202 GLN C CA  1 -0.212 0.052  0.125  
ATOM   7767  C  C   . GLN C 1 213 ? -23.339 7.091   49.625  1    122.01 ? 202 GLN C C   1 -0.214 0.065  0.124  
ATOM   7768  O  O   . GLN C 1 213 ? -22.867 8.034   50.27   1    124.61 ? 202 GLN C O   1 -0.21  0.074  0.126  
ATOM   7769  C  CB  . GLN C 1 213 ? -22.035 4.98    49.335  1    117.15 ? 202 GLN C CB  1 -0.202 0.046  0.123  
ATOM   7770  C  CG  . GLN C 1 213 ? -20.875 4.602   50.21   1    118.21 ? 202 GLN C CG  1 -0.191 0.042  0.125  
ATOM   7771  C  CD  . GLN C 1 213 ? -20.096 5.799   50.697  1    126.85 ? 202 GLN C CD  1 -0.184 0.053  0.127  
ATOM   7772  O  OE1 . GLN C 1 213 ? -20.454 6.943   50.418  1    129.18 ? 202 GLN C OE1 1 -0.187 0.064  0.126  
ATOM   7773  N  NE2 . GLN C 1 213 ? -19.014 5.542   51.433  1    131.07 ? 202 GLN C NE2 1 -0.174 0.051  0.128  
ATOM   7774  N  N   . ALA C 1 214 ? -24.047 7.28    48.505  1    119.03 ? 203 ALA C N   1 -0.22  0.067  0.121  
ATOM   7775  C  CA  . ALA C 1 214 ? -24.195 8.622   47.946  1    121.93 ? 203 ALA C CA  1 -0.222 0.079  0.12   
ATOM   7776  C  C   . ALA C 1 214 ? -24.739 9.616   48.972  1    123.41 ? 203 ALA C C   1 -0.227 0.088  0.122  
ATOM   7777  O  O   . ALA C 1 214 ? -24.347 10.79   48.961  1    125.73 ? 203 ALA C O   1 -0.223 0.099  0.122  
ATOM   7778  C  CB  . ALA C 1 214 ? -25.087 8.583   46.7    1    115.87 ? 203 ALA C CB  1 -0.23  0.079  0.117  
ATOM   7779  N  N   . GLU C 1 215 ? -25.608 9.167   49.887  1    121.6  ? 204 GLU C N   1 -0.235 0.084  0.125  
ATOM   7780  C  CA  . GLU C 1 215 ? -26.109 10.066  50.932  1    127.55 ? 204 GLU C CA  1 -0.239 0.092  0.127  
ATOM   7781  C  C   . GLU C 1 215 ? -25.03  10.38   51.974  1    125.03 ? 204 GLU C C   1 -0.229 0.095  0.13   
ATOM   7782  O  O   . GLU C 1 215 ? -24.874 11.533  52.39   1    124.9  ? 204 GLU C O   1 -0.228 0.106  0.131  
ATOM   7783  C  CB  . GLU C 1 215 ? -27.347 9.463   51.604  1    122.87 ? 204 GLU C CB  1 -0.251 0.087  0.129  
ATOM   7784  C  CG  . GLU C 1 215 ? -27.671 10.12   52.933  1    129.6  ? 204 GLU C CG  1 -0.254 0.093  0.132  
ATOM   7785  C  CD  . GLU C 1 215 ? -29.069 9.807   53.467  1    140.65 ? 204 GLU C CD  1 -0.266 0.09   0.133  
ATOM   7786  O  OE1 . GLU C 1 215 ? -29.521 8.643   53.347  1    138.72 ? 204 GLU C OE1 1 -0.271 0.079  0.133  
ATOM   7787  O  OE2 . GLU C 1 215 ? -29.711 10.739  54.021  1    142.83 ? 204 GLU C OE2 1 -0.272 0.098  0.135  
ATOM   7788  N  N   . LEU C 1 216 ? -24.258 9.375   52.39   1    122.5  ? 205 LEU C N   1 -0.222 0.086  0.131  
ATOM   7789  C  CA  . LEU C 1 216 ? -23.285 9.524   53.466  1    122.32 ? 205 LEU C CA  1 -0.213 0.087  0.133  
ATOM   7790  C  C   . LEU C 1 216 ? -21.922 10.003  52.974  1    126.42 ? 205 LEU C C   1 -0.201 0.092  0.132  
ATOM   7791  O  O   . LEU C 1 216 ? -20.89  9.621   53.557  1    129.31 ? 205 LEU C O   1 -0.191 0.088  0.134  
ATOM   7792  C  CB  . LEU C 1 216 ? -23.122 8.201   54.222  1    110.31 ? 205 LEU C CB  1 -0.212 0.075  0.135  
ATOM   7793  C  CG  . LEU C 1 216 ? -24.193 7.579   55.125  1    108.13 ? 205 LEU C CG  1 -0.222 0.069  0.138  
ATOM   7794  C  CD1 . LEU C 1 216 ? -25.63  7.636   54.599  1    105.59 ? 205 LEU C CD1 1 -0.235 0.07   0.136  
ATOM   7795  C  CD2 . LEU C 1 216 ? -23.789 6.134   55.339  1    114.58 ? 205 LEU C CD2 1 -0.218 0.056  0.138  
ATOM   7796  N  N   . SER C 1 217 ? -21.883 10.841  51.931  1    126.19 ? 206 SER C N   1 -0.201 0.099  0.13   
ATOM   7797  C  CA  . SER C 1 217 ? -20.62  11.266  51.319  1    134.07 ? 206 SER C CA  1 -0.189 0.103  0.128  
ATOM   7798  C  C   . SER C 1 217 ? -20.569 12.741  50.957  1    138.06 ? 206 SER C C   1 -0.188 0.117  0.127  
ATOM   7799  O  O   . SER C 1 217 ? -19.461 13.281  50.817  1    135.79 ? 206 SER C O   1 -0.178 0.122  0.127  
ATOM   7800  C  CB  . SER C 1 217 ? -20.329 10.459  50.046  1    137.22 ? 206 SER C CB  1 -0.186 0.096  0.125  
ATOM   7801  O  OG  . SER C 1 217 ? -20.775 9.124   50.154  1    134.96 ? 206 SER C OG  1 -0.19  0.084  0.125  
ATOM   7802  N  N   . SER C 1 218 ? -21.693 13.409  50.751  1    141.63 ? 207 SER C N   1 -0.199 0.123  0.127  
ATOM   7803  C  CA  . SER C 1 218 ? -21.72  14.79   50.309  1    147.69 ? 207 SER C CA  1 -0.199 0.136  0.126  
ATOM   7804  C  C   . SER C 1 218 ? -22.225 15.7    51.425  1    151.89 ? 207 SER C C   1 -0.204 0.144  0.128  
ATOM   7805  O  O   . SER C 1 218 ? -22.896 15.256  52.366  1    147.38 ? 207 SER C O   1 -0.21  0.14   0.131  
ATOM   7806  C  CB  . SER C 1 218 ? -22.598 14.938  49.056  1    145.52 ? 207 SER C CB  1 -0.207 0.137  0.122  
ATOM   7807  O  OG  . SER C 1 218 ? -23.824 14.238  49.218  1    144.18 ? 207 SER C OG  1 -0.218 0.13   0.123  
ATOM   7808  N  N   . ALA C 1 219 ? -21.88  16.99   51.31   1    154.13 ? 208 ALA C N   1 -0.201 0.156  0.128  
ATOM   7809  C  CA  . ALA C 1 219 ? -22.342 17.975  52.282  1    150.01 ? 208 ALA C CA  1 -0.205 0.165  0.131  
ATOM   7810  C  C   . ALA C 1 219 ? -23.863 17.966  52.37   1    152.06 ? 208 ALA C C   1 -0.219 0.165  0.131  
ATOM   7811  O  O   . ALA C 1 219 ? -24.433 17.88   53.467  1    147.09 ? 208 ALA C O   1 -0.224 0.164  0.133  
ATOM   7812  C  CB  . ALA C 1 219 ? -21.816 19.366  51.913  1    142.85 ? 208 ALA C CB  1 -0.2   0.177  0.13   
ATOM   7813  N  N   . GLN C 1 220 ? -24.537 18.036  51.215  1    145.54 ? 209 GLN C N   1 -0.225 0.165  0.128  
ATOM   7814  C  CA  . GLN C 1 220 ? -25.973 17.853  51.109  1    141.95 ? 209 GLN C CA  1 -0.238 0.164  0.128  
ATOM   7815  C  C   . GLN C 1 220 ? -26.262 16.615  50.269  1    140.58 ? 209 GLN C C   1 -0.241 0.152  0.126  
ATOM   7816  O  O   . GLN C 1 220 ? -25.519 16.331  49.326  1    143.75 ? 209 GLN C O   1 -0.234 0.15   0.123  
ATOM   7817  C  CB  . GLN C 1 220 ? -26.652 19.079  50.476  1    138.99 ? 209 GLN C CB  1 -0.244 0.175  0.126  
ATOM   7818  C  CG  . GLN C 1 220 ? -26.004 20.413  50.858  1    148.73 ? 209 GLN C CG  1 -0.238 0.187  0.127  
ATOM   7819  C  CD  . GLN C 1 220 ? -27.017 21.52   51.153  1    150.31 ? 209 GLN C CD  1 -0.248 0.197  0.128  
ATOM   7820  O  OE1 . GLN C 1 220 ? -28.208 21.256  51.342  1    148.3  ? 209 GLN C OE1 1 -0.259 0.195  0.128  
ATOM   7821  N  NE2 . GLN C 1 220 ? -26.541 22.768  51.198  1    142.46 ? 209 GLN C NE2 1 -0.243 0.209  0.128  
ATOM   7822  N  N   . PRO C 1 221 ? -27.298 15.851  50.596  1    142.12 ? 210 PRO C N   1 -0.25  0.145  0.126  
ATOM   7823  C  CA  . PRO C 1 221 ? -27.588 14.618  49.836  1    140.31 ? 210 PRO C CA  1 -0.253 0.134  0.124  
ATOM   7824  C  C   . PRO C 1 221 ? -28.139 14.926  48.451  1    135.74 ? 210 PRO C C   1 -0.258 0.137  0.121  
ATOM   7825  O  O   . PRO C 1 221 ? -29.103 15.696  48.298  1    130.48 ? 210 PRO C O   1 -0.267 0.144  0.121  
ATOM   7826  C  CB  . PRO C 1 221 ? -28.626 13.896  50.712  1    139.82 ? 210 PRO C CB  1 -0.262 0.127  0.127  
ATOM   7827  C  CG  . PRO C 1 221 ? -28.455 14.484  52.082  1    135.39 ? 210 PRO C CG  1 -0.261 0.133  0.13   
ATOM   7828  C  CD  . PRO C 1 221 ? -28.07  15.921  51.848  1    138.83 ? 210 PRO C CD  1 -0.257 0.146  0.129  
ATOM   7829  N  N   . PRO C 1 222 ? -27.567 14.32   47.414  1    131.84 ? 211 PRO C N   1 -0.253 0.131  0.118  
ATOM   7830  C  CA  . PRO C 1 222 ? -27.93  14.695  46.047  1    133.15 ? 211 PRO C CA  1 -0.256 0.135  0.115  
ATOM   7831  C  C   . PRO C 1 222 ? -29.297 14.157  45.652  1    131.39 ? 211 PRO C C   1 -0.268 0.13   0.114  
ATOM   7832  O  O   . PRO C 1 222 ? -29.832 13.228  46.262  1    128.05 ? 211 PRO C O   1 -0.273 0.121  0.116  
ATOM   7833  C  CB  . PRO C 1 222 ? -26.816 14.059  45.208  1    130.43 ? 211 PRO C CB  1 -0.246 0.129  0.113  
ATOM   7834  C  CG  . PRO C 1 222 ? -26.406 12.855  46.016  1    123.72 ? 211 PRO C CG  1 -0.242 0.118  0.115  
ATOM   7835  C  CD  . PRO C 1 222 ? -26.562 13.241  47.449  1    131.13 ? 211 PRO C CD  1 -0.243 0.121  0.118  
ATOM   7836  N  N   . LYS C 1 223 ? -29.871 14.784  44.62   1    128.59 ? 212 LYS C N   1 -0.274 0.135  0.111  
ATOM   7837  C  CA  . LYS C 1 223 ? -31.049 14.229  43.965  1    126.89 ? 212 LYS C CA  1 -0.285 0.13   0.11   
ATOM   7838  C  C   . LYS C 1 223 ? -30.684 12.918  43.284  1    129.38 ? 212 LYS C C   1 -0.281 0.118  0.108  
ATOM   7839  O  O   . LYS C 1 223 ? -29.64  12.805  42.631  1    128.29 ? 212 LYS C O   1 -0.272 0.117  0.106  
ATOM   7840  C  CB  . LYS C 1 223 ? -31.609 15.213  42.931  1    122.59 ? 212 LYS C CB  1 -0.29  0.139  0.107  
ATOM   7841  C  CG  . LYS C 1 223 ? -32.814 16.015  43.397  1    131.16 ? 212 LYS C CG  1 -0.301 0.147  0.108  
ATOM   7842  C  CD  . LYS C 1 223 ? -32.499 16.825  44.66   1    136.91 ? 212 LYS C CD  1 -0.298 0.154  0.112  
ATOM   7843  C  CE  . LYS C 1 223 ? -33.635 17.776  45.028  1    132.36 ? 212 LYS C CE  1 -0.308 0.163  0.112  
ATOM   7844  N  NZ  . LYS C 1 223 ? -33.11  19.087  45.495  1    125.24 ? 212 LYS C NZ  1 -0.303 0.175  0.114  
ATOM   7845  N  N   . PHE C 1 224 ? -31.538 11.914  43.446  1    128.09 ? 213 PHE C N   1 -0.289 0.109  0.108  
ATOM   7846  C  CA  . PHE C 1 224 ? -31.313 10.614  42.835  1    123.05 ? 213 PHE C CA  1 -0.287 0.097  0.107  
ATOM   7847  C  C   . PHE C 1 224 ? -32.303 10.447  41.704  1    121.65 ? 213 PHE C C   1 -0.296 0.096  0.104  
ATOM   7848  O  O   . PHE C 1 224 ? -33.517 10.558  41.915  1    120.34 ? 213 PHE C O   1 -0.307 0.097  0.105  
ATOM   7849  C  CB  . PHE C 1 224 ? -31.454 9.475   43.839  1    120.74 ? 213 PHE C CB  1 -0.288 0.087  0.109  
ATOM   7850  C  CG  . PHE C 1 224 ? -30.387 9.46    44.874  1    125.04 ? 213 PHE C CG  1 -0.278 0.087  0.112  
ATOM   7851  C  CD1 . PHE C 1 224 ? -30.491 10.253  46.004  1    123.99 ? 213 PHE C CD1 1 -0.279 0.094  0.115  
ATOM   7852  C  CD2 . PHE C 1 224 ? -29.27  8.657   44.724  1    123.54 ? 213 PHE C CD2 1 -0.268 0.079  0.112  
ATOM   7853  C  CE1 . PHE C 1 224 ? -29.495 10.249  46.963  1    119.75 ? 213 PHE C CE1 1 -0.27  0.094  0.117  
ATOM   7854  C  CE2 . PHE C 1 224 ? -28.276 8.642   45.692  1    119.78 ? 213 PHE C CE2 1 -0.259 0.079  0.114  
ATOM   7855  C  CZ  . PHE C 1 224 ? -28.388 9.444   46.805  1    116.61 ? 213 PHE C CZ  1 -0.26  0.087  0.117  
ATOM   7856  N  N   . VAL C 1 225 ? -31.777 10.216  40.506  1    120.79 ? 214 VAL C N   1 -0.291 0.094  0.101  
ATOM   7857  C  CA  . VAL C 1 225 ? -32.563 9.853   39.338  1    114.75 ? 214 VAL C CA  1 -0.298 0.09   0.098  
ATOM   7858  C  C   . VAL C 1 225 ? -32.108 8.466   38.916  1    112.42 ? 214 VAL C C   1 -0.294 0.078  0.097  
ATOM   7859  O  O   . VAL C 1 225 ? -30.909 8.222   38.731  1    110.92 ? 214 VAL C O   1 -0.283 0.075  0.097  
ATOM   7860  C  CB  . VAL C 1 225 ? -32.408 10.878  38.201  1    109.83 ? 214 VAL C CB  1 -0.297 0.1    0.095  
ATOM   7861  C  CG1 . VAL C 1 225 ? -33.097 10.384  36.918  1    116.16 ? 214 VAL C CG1 1 -0.303 0.095  0.092  
ATOM   7862  C  CG2 . VAL C 1 225 ? -32.985 12.205  38.626  1    110.46 ? 214 VAL C CG2 1 -0.302 0.112  0.096  
ATOM   7863  N  N   . ILE C 1 226 ? -33.066 7.558   38.779  1    110.92 ? 215 ILE C N   1 -0.303 0.069  0.097  
ATOM   7864  C  CA  . ILE C 1 226 ? -32.796 6.158   38.498  1    112.62 ? 215 ILE C CA  1 -0.301 0.056  0.096  
ATOM   7865  C  C   . ILE C 1 226 ? -33.628 5.713   37.292  1    110.55 ? 215 ILE C C   1 -0.308 0.052  0.093  
ATOM   7866  O  O   . ILE C 1 226 ? -34.854 5.562   37.394  1    107.64 ? 215 ILE C O   1 -0.319 0.051  0.093  
ATOM   7867  C  CB  . ILE C 1 226 ? -33.092 5.291   39.721  1    116.8  ? 215 ILE C CB  1 -0.303 0.048  0.099  
ATOM   7868  C  CG1 . ILE C 1 226 ? -32.273 5.788   40.915  1    118.45 ? 215 ILE C CG1 1 -0.296 0.053  0.102  
ATOM   7869  C  CG2 . ILE C 1 226 ? -32.799 3.869   39.424  1    110.89 ? 215 ILE C CG2 1 -0.301 0.035  0.098  
ATOM   7870  C  CD1 . ILE C 1 226 ? -33.068 6.749   41.818  1    125.33 ? 215 ILE C CD1 1 -0.303 0.062  0.104  
ATOM   7871  N  N   . ILE C 1 227 ? -32.971 5.492   36.156  1    111.07 ? 216 ILE C N   1 -0.302 0.05   0.09   
ATOM   7872  C  CA  . ILE C 1 227 ? -33.637 4.952   34.976  1    111.86 ? 216 ILE C CA  1 -0.308 0.045  0.087  
ATOM   7873  C  C   . ILE C 1 227 ? -33.155 3.524   34.79   1    108.4  ? 216 ILE C C   1 -0.304 0.032  0.087  
ATOM   7874  O  O   . ILE C 1 227 ? -31.951 3.282   34.635  1    107.93 ? 216 ILE C O   1 -0.293 0.03   0.086  
ATOM   7875  C  CB  . ILE C 1 227 ? -33.381 5.799   33.721  1    107.36 ? 216 ILE C CB  1 -0.306 0.053  0.084  
ATOM   7876  C  CG1 . ILE C 1 227 ? -33.646 7.275   34.02   1    108.47 ? 216 ILE C CG1 1 -0.308 0.067  0.085  
ATOM   7877  C  CG2 . ILE C 1 227 ? -34.283 5.332   32.614  1    105.06 ? 216 ILE C CG2 1 -0.314 0.049  0.081  
ATOM   7878  C  CD1 . ILE C 1 227 ? -33.85  8.144   32.809  1    105.02 ? 216 ILE C CD1 1 -0.31  0.075  0.082  
ATOM   7879  N  N   . GLY C 1 228 ? -34.088 2.577   34.832  1    103.59 ? 217 GLY C N   1 -0.312 0.024  0.087  
ATOM   7880  C  CA  . GLY C 1 228 ? -33.729 1.176   34.768  1    108.01 ? 217 GLY C CA  1 -0.309 0.011  0.087  
ATOM   7881  C  C   . GLY C 1 228 ? -34.513 0.508   33.673  1    106.57 ? 217 GLY C C   1 -0.316 0.005  0.084  
ATOM   7882  O  O   . GLY C 1 228 ? -35.748 0.536   33.689  1    105.76 ? 217 GLY C O   1 -0.328 0.005  0.084  
ATOM   7883  N  N   . THR C 1 229 ? -33.799 -0.099  32.72   1    111.75 ? 218 THR C N   1 -0.31  -0.001 0.082  
ATOM   7884  C  CA  . THR C 1 229 ? -34.347 -0.422  31.408  1    107.97 ? 218 THR C CA  1 -0.315 -0.004 0.078  
ATOM   7885  C  C   . THR C 1 229 ? -34.439 -1.909  31.101  1    105.63 ? 218 THR C C   1 -0.316 -0.017 0.078  
ATOM   7886  O  O   . THR C 1 229 ? -35.002 -2.262  30.059  1    108.35 ? 218 THR C O   1 -0.321 -0.021 0.075  
ATOM   7887  C  CB  . THR C 1 229 ? -33.502 0.25    30.321  1    101.36 ? 218 THR C CB  1 -0.307 0.002  0.076  
ATOM   7888  O  OG1 . THR C 1 229 ? -32.132 0.258   30.756  1    102.42 ? 218 THR C OG1 1 -0.294 0.002  0.077  
ATOM   7889  C  CG2 . THR C 1 229 ? -34.003 1.678   30.076  1    94.54  ? 218 THR C CG2 1 -0.312 0.015  0.075  
ATOM   7890  N  N   . ASP C 1 230 ? -33.885 -2.78   31.949  1    104.99 ? 219 ASP C N   1 -0.311 -0.025 0.08   
ATOM   7891  C  CA  . ASP C 1 230 ? -34.182 -4.206  31.978  1    104.25 ? 219 ASP C CA  1 -0.313 -0.039 0.08   
ATOM   7892  C  C   . ASP C 1 230 ? -35.645 -4.463  31.602  1    105.02 ? 219 ASP C C   1 -0.327 -0.041 0.079  
ATOM   7893  O  O   . ASP C 1 230 ? -36.522 -3.655  31.935  1    105.61 ? 219 ASP C O   1 -0.335 -0.033 0.08   
ATOM   7894  C  CB  . ASP C 1 230 ? -33.855 -4.736  33.383  1    106.94 ? 219 ASP C CB  1 -0.31  -0.043 0.083  
ATOM   7895  C  CG  . ASP C 1 230 ? -33.711 -6.247  33.447  1    106.03 ? 219 ASP C CG  1 -0.309 -0.057 0.084  
ATOM   7896  O  OD1 . ASP C 1 230 ? -34.743 -6.951  33.387  1    103.98 ? 219 ASP C OD1 1 -0.318 -0.064 0.083  
ATOM   7897  O  OD2 . ASP C 1 230 ? -32.554 -6.72   33.583  1    102.26 ? 219 ASP C OD2 1 -0.298 -0.062 0.084  
ATOM   7898  N  N   . VAL C 1 231 ? -35.944 -5.549  30.886  1    100.4  ? 220 VAL C N   1 -0.329 -0.051 0.077  
ATOM   7899  C  CA  . VAL C 1 231 ? -37.333 -5.728  30.475  1    105.15 ? 220 VAL C CA  1 -0.342 -0.052 0.076  
ATOM   7900  C  C   . VAL C 1 231 ? -38.198 -6.111  31.67   1    104.8  ? 220 VAL C C   1 -0.35  -0.056 0.079  
ATOM   7901  O  O   . VAL C 1 231 ? -39.41  -5.849  31.672  1    102.04 ? 220 VAL C O   1 -0.361 -0.054 0.079  
ATOM   7902  C  CB  . VAL C 1 231 ? -37.457 -6.745  29.309  1    105.44 ? 220 VAL C CB  1 -0.343 -0.062 0.073  
ATOM   7903  C  CG1 . VAL C 1 231 ? -37.174 -8.183  29.743  1    105.2  ? 220 VAL C CG1 1 -0.341 -0.075 0.074  
ATOM   7904  C  CG2 . VAL C 1 231 ? -38.82  -6.633  28.631  1    100.79 ? 220 VAL C CG2 1 -0.356 -0.061 0.071  
ATOM   7905  N  N   . ASN C 1 232 ? -37.591 -6.679  32.708  1    109.74 ? 221 ASN C N   1 -0.344 -0.061 0.082  
ATOM   7906  C  CA  . ASN C 1 232 ? -38.271 -7.045  33.941  1    114.02 ? 221 ASN C CA  1 -0.351 -0.065 0.085  
ATOM   7907  C  C   . ASN C 1 232 ? -38.269 -5.888  34.943  1    109.06 ? 221 ASN C C   1 -0.351 -0.054 0.087  
ATOM   7908  O  O   . ASN C 1 232 ? -37.346 -5.067  34.972  1    106.12 ? 221 ASN C O   1 -0.342 -0.046 0.087  
ATOM   7909  C  CB  . ASN C 1 232 ? -37.593 -8.274  34.543  1    114.22 ? 221 ASN C CB  1 -0.345 -0.076 0.086  
ATOM   7910  C  CG  . ASN C 1 232 ? -37.195 -9.28   33.484  1    108.3  ? 221 ASN C CG  1 -0.341 -0.085 0.084  
ATOM   7911  O  OD1 . ASN C 1 232 ? -36.054 -9.296  33.03   1    104.52 ? 221 ASN C OD1 1 -0.33  -0.085 0.082  
ATOM   7912  N  ND2 . ASN C 1 232 ? -38.147 -10.109 33.067  1    108.77 ? 221 ASN C ND2 1 -0.35  -0.093 0.083  
ATOM   7913  N  N   . ARG C 1 233 ? -39.319 -5.831  35.765  1    107.48 ? 222 ARG C N   1 -0.36  -0.053 0.089  
ATOM   7914  C  CA  . ARG C 1 233 ? -39.464 -4.757  36.745  1    112.93 ? 222 ARG C CA  1 -0.362 -0.044 0.092  
ATOM   7915  C  C   . ARG C 1 233 ? -38.319 -4.751  37.762  1    111.84 ? 222 ARG C C   1 -0.351 -0.044 0.094  
ATOM   7916  O  O   . ARG C 1 233 ? -37.724 -5.788  38.075  1    110.3  ? 222 ARG C O   1 -0.346 -0.053 0.095  
ATOM   7917  C  CB  . ARG C 1 233 ? -40.813 -4.895  37.455  1    115.13 ? 222 ARG C CB  1 -0.374 -0.045 0.094  
ATOM   7918  C  CG  . ARG C 1 233 ? -40.963 -4.063  38.706  1    116.42 ? 222 ARG C CG  1 -0.375 -0.037 0.097  
ATOM   7919  C  CD  . ARG C 1 233 ? -42.298 -3.331  38.795  1    119.35 ? 222 ARG C CD  1 -0.388 -0.031 0.097  
ATOM   7920  N  NE  . ARG C 1 233 ? -42.491 -2.815  40.147  1    123.13 ? 222 ARG C NE  1 -0.389 -0.026 0.1    
ATOM   7921  C  CZ  . ARG C 1 233 ? -43.058 -3.498  41.136  1    126.86 ? 222 ARG C CZ  1 -0.395 -0.032 0.103  
ATOM   7922  N  NH1 . ARG C 1 233 ? -43.593 -4.693  40.932  1    126.78 ? 222 ARG C NH1 1 -0.399 -0.043 0.102  
ATOM   7923  N  NH2 . ARG C 1 233 ? -43.079 -2.971  42.363  1    124.81 ? 222 ARG C NH2 1 -0.395 -0.027 0.106  
ATOM   7924  N  N   . ASP C 1 234 ? -37.995 -3.554  38.269  1    112.19 ? 223 ASP C N   1 -0.348 -0.033 0.096  
ATOM   7925  C  CA  . ASP C 1 234 ? -37.048 -3.403  39.387  1    116.09 ? 223 ASP C CA  1 -0.34  -0.031 0.098  
ATOM   7926  C  C   . ASP C 1 234 ? -37.788 -3.514  40.725  1    113.65 ? 223 ASP C C   1 -0.346 -0.032 0.102  
ATOM   7927  O  O   . ASP C 1 234 ? -37.912 -2.547  41.48   1    116.44 ? 223 ASP C O   1 -0.347 -0.023 0.104  
ATOM   7928  C  CB  . ASP C 1 234 ? -36.311 -2.066  39.306  1    116.69 ? 223 ASP C CB  1 -0.333 -0.019 0.098  
ATOM   7929  C  CG  . ASP C 1 234 ? -35.899 -1.695  37.907  1    111.5  ? 223 ASP C CG  1 -0.329 -0.016 0.095  
ATOM   7930  O  OD1 . ASP C 1 234 ? -36.793 -1.608  37.057  1    116.34 ? 223 ASP C OD1 1 -0.337 -0.015 0.093  
ATOM   7931  O  OD2 . ASP C 1 234 ? -34.692 -1.462  37.664  1    104    ? 223 ASP C OD2 1 -0.318 -0.013 0.094  
ATOM   7932  N  N   . ASN C 1 235 ? -38.287 -4.722  41.021  1    111.58 ? 224 ASN C N   1 -0.351 -0.043 0.102  
ATOM   7933  C  CA  . ASN C 1 235 ? -39.099 -4.895  42.227  1    115.92 ? 224 ASN C CA  1 -0.358 -0.045 0.105  
ATOM   7934  C  C   . ASN C 1 235 ? -38.238 -4.801  43.482  1    114.25 ? 224 ASN C C   1 -0.35  -0.044 0.109  
ATOM   7935  O  O   . ASN C 1 235 ? -38.5   -3.975  44.363  1    110.41 ? 224 ASN C O   1 -0.353 -0.036 0.111  
ATOM   7936  C  CB  . ASN C 1 235 ? -39.868 -6.22   42.184  1    113.83 ? 224 ASN C CB  1 -0.365 -0.057 0.105  
ATOM   7937  C  CG  . ASN C 1 235 ? -38.984 -7.413  41.847  1    118.24 ? 224 ASN C CG  1 -0.357 -0.068 0.104  
ATOM   7938  O  OD1 . ASN C 1 235 ? -37.788 -7.261  41.576  1    118.11 ? 224 ASN C OD1 1 -0.346 -0.067 0.104  
ATOM   7939  N  ND2 . ASN C 1 235 ? -39.57  -8.611  41.864  1    117.69 ? 224 ASN C ND2 1 -0.363 -0.079 0.105  
ATOM   7940  N  N   . GLY C 1 236 ? -37.199 -5.628  43.57   1    111.93 ? 225 GLY C N   1 -0.341 -0.052 0.109  
ATOM   7941  C  CA  . GLY C 1 236 ? -36.182 -5.499  44.589  1    108.26 ? 225 GLY C CA  1 -0.332 -0.05  0.111  
ATOM   7942  C  C   . GLY C 1 236 ? -35.821 -4.074  44.954  1    110.91 ? 225 GLY C C   1 -0.328 -0.037 0.112  
ATOM   7943  O  O   . GLY C 1 236 ? -36.061 -3.651  46.085  1    119.76 ? 225 GLY C O   1 -0.33  -0.033 0.115  
ATOM   7944  N  N   . LEU C 1 237 ? -35.252 -3.318  44.015  1    112.42 ? 226 LEU C N   1 -0.323 -0.03  0.11   
ATOM   7945  C  CA  . LEU C 1 237 ? -34.846 -1.957  44.337  1    112.78 ? 226 LEU C CA  1 -0.319 -0.018 0.111  
ATOM   7946  C  C   . LEU C 1 237 ? -36.044 -1.108  44.741  1    116.32 ? 226 LEU C C   1 -0.33  -0.01  0.112  
ATOM   7947  O  O   . LEU C 1 237 ? -35.934 -0.271  45.646  1    120.62 ? 226 LEU C O   1 -0.329 -0.002 0.114  
ATOM   7948  C  CB  . LEU C 1 237 ? -34.111 -1.324  43.157  1    114.77 ? 226 LEU C CB  1 -0.313 -0.012 0.108  
ATOM   7949  C  CG  . LEU C 1 237 ? -33.592 0.09    43.417  1    118.27 ? 226 LEU C CG  1 -0.308 0.001  0.108  
ATOM   7950  C  CD1 . LEU C 1 237 ? -32.071 0.155   43.31   1    113.04 ? 226 LEU C CD1 1 -0.294 0.001  0.108  
ATOM   7951  C  CD2 . LEU C 1 237 ? -34.245 1.072   42.457  1    120.35 ? 226 LEU C CD2 1 -0.314 0.01   0.106  
ATOM   7952  N  N   . CYS C 1 238 ? -37.204 -1.333  44.109  1    115.35 ? 227 CYS C N   1 -0.341 -0.012 0.11   
ATOM   7953  C  CA  . CYS C 1 238 ? -38.395 -0.545  44.435  1    118.87 ? 227 CYS C CA  1 -0.352 -0.005 0.111  
ATOM   7954  C  C   . CYS C 1 238 ? -38.769 -0.681  45.907  1    118.44 ? 227 CYS C C   1 -0.355 -0.006 0.115  
ATOM   7955  O  O   . CYS C 1 238 ? -39.21  0.289   46.536  1    119.38 ? 227 CYS C O   1 -0.359 0.003  0.116  
ATOM   7956  C  CB  . CYS C 1 238 ? -39.576 -0.968  43.552  1    117.53 ? 227 CYS C CB  1 -0.363 -0.009 0.109  
ATOM   7957  S  SG  . CYS C 1 238 ? -41.078 0.072   43.691  1    120.29 ? 227 CYS C SG  1 -0.376 0.001  0.109  
ATOM   7958  N  N   . ASP C 1 239 ? -38.599 -1.88   46.471  1    114.82 ? 228 ASP C N   1 -0.354 -0.017 0.116  
ATOM   7959  C  CA  . ASP C 1 239 ? -38.969 -2.124  47.857  1    117.37 ? 228 ASP C CA  1 -0.357 -0.019 0.119  
ATOM   7960  C  C   . ASP C 1 239 ? -37.929 -1.549  48.814  1    116.4  ? 228 ASP C C   1 -0.348 -0.014 0.122  
ATOM   7961  O  O   . ASP C 1 239 ? -38.272 -0.785  49.722  1    115.88 ? 228 ASP C O   1 -0.351 -0.007 0.124  
ATOM   7962  C  CB  . ASP C 1 239 ? -39.162 -3.624  48.086  1    115.46 ? 228 ASP C CB  1 -0.359 -0.033 0.12   
ATOM   7963  C  CG  . ASP C 1 239 ? -39.552 -3.952  49.519  1    124.95 ? 228 ASP C CG  1 -0.362 -0.036 0.124  
ATOM   7964  O  OD1 . ASP C 1 239 ? -40.512 -3.328  50.032  1    128.44 ? 228 ASP C OD1 1 -0.371 -0.03  0.125  
ATOM   7965  O  OD2 . ASP C 1 239 ? -38.904 -4.835  50.13   1    123    ? 228 ASP C OD2 1 -0.357 -0.044 0.125  
ATOM   7966  N  N   . ILE C 1 240 ? -36.653 -1.897  48.611  1    109.65 ? 229 ILE C N   1 -0.336 -0.017 0.121  
ATOM   7967  C  CA  . ILE C 1 240 ? -35.582 -1.347  49.437  1    108.68 ? 229 ILE C CA  1 -0.326 -0.012 0.123  
ATOM   7968  C  C   . ILE C 1 240 ? -35.639 0.169   49.462  1    115.57 ? 229 ILE C C   1 -0.327 0.002  0.123  
ATOM   7969  O  O   . ILE C 1 240 ? -35.246 0.794   50.453  1    121.27 ? 229 ILE C O   1 -0.323 0.007  0.126  
ATOM   7970  C  CB  . ILE C 1 240 ? -34.203 -1.832  48.948  1    110.99 ? 229 ILE C CB  1 -0.313 -0.017 0.122  
ATOM   7971  C  CG1 . ILE C 1 240 ? -34.215 -3.329  48.666  1    113.78 ? 229 ILE C CG1 1 -0.314 -0.031 0.122  
ATOM   7972  C  CG2 . ILE C 1 240 ? -33.101 -1.496  49.962  1    105.67 ? 229 ILE C CG2 1 -0.303 -0.014 0.125  
ATOM   7973  C  CD1 . ILE C 1 240 ? -33.111 -3.735  47.715  1    114.64 ? 229 ILE C CD1 1 -0.303 -0.034 0.119  
ATOM   7974  N  N   . LEU C 1 241 ? -36.124 0.795   48.389  1    114.82 ? 230 LEU C N   1 -0.331 0.007  0.121  
ATOM   7975  C  CA  . LEU C 1 241 ? -36.284 2.245   48.426  1    121.05 ? 230 LEU C CA  1 -0.333 0.021  0.121  
ATOM   7976  C  C   . LEU C 1 241 ? -37.481 2.64    49.287  1    125.54 ? 230 LEU C C   1 -0.343 0.024  0.123  
ATOM   7977  O  O   . LEU C 1 241 ? -37.359 3.473   50.2    1    124.95 ? 230 LEU C O   1 -0.342 0.032  0.125  
ATOM   7978  C  CB  . LEU C 1 241 ? -36.419 2.809   47.01   1    117.63 ? 230 LEU C CB  1 -0.334 0.026  0.117  
ATOM   7979  C  CG  . LEU C 1 241 ? -35.202 2.743   46.071  1    120.76 ? 230 LEU C CG  1 -0.323 0.025  0.115  
ATOM   7980  C  CD1 . LEU C 1 241 ? -35.186 3.959   45.17   1    121.88 ? 230 LEU C CD1 1 -0.322 0.036  0.113  
ATOM   7981  C  CD2 . LEU C 1 241 ? -33.864 2.596   46.798  1    117.61 ? 230 LEU C CD2 1 -0.31  0.024  0.117  
ATOM   7982  N  N   . ARG C 1 242 ? -38.638 2.021   49.033  1    121.2  ? 231 ARG C N   1 -0.354 0.019  0.122  
ATOM   7983  C  CA  . ARG C 1 242 ? -39.86  2.388   49.741  1    121.96 ? 231 ARG C CA  1 -0.365 0.022  0.124  
ATOM   7984  C  C   . ARG C 1 242 ? -39.728 2.227   51.256  1    130.63 ? 231 ARG C C   1 -0.364 0.02   0.128  
ATOM   7985  O  O   . ARG C 1 242 ? -40.373 2.966   52.015  1    130.6  ? 231 ARG C O   1 -0.37  0.027  0.13   
ATOM   7986  C  CB  . ARG C 1 242 ? -41.01  1.542   49.219  1    121.36 ? 231 ARG C CB  1 -0.376 0.014  0.123  
ATOM   7987  C  CG  . ARG C 1 242 ? -42.363 2.156   49.401  1    126.01 ? 231 ARG C CG  1 -0.388 0.02   0.123  
ATOM   7988  C  CD  . ARG C 1 242 ? -43.412 1.13    49.05   1    130.93 ? 231 ARG C CD  1 -0.398 0.01   0.122  
ATOM   7989  N  NE  . ARG C 1 242 ? -43.151 -0.126  49.738  1    133.74 ? 231 ARG C NE  1 -0.395 -0.001 0.124  
ATOM   7990  C  CZ  . ARG C 1 242 ? -43.924 -0.635  50.687  1    142.63 ? 231 ARG C CZ  1 -0.403 -0.006 0.127  
ATOM   7991  N  NH1 . ARG C 1 242 ? -45.063 -0.053  51.039  1    146.09 ? 231 ARG C NH1 1 -0.413 -0.0   0.127  
ATOM   7992  N  NH2 . ARG C 1 242 ? -43.552 -1.763  51.291  1    139.72 ? 231 ARG C NH2 1 -0.399 -0.016 0.128  
ATOM   7993  N  N   . HIS C 1 243 ? -38.903 1.281   51.717  1    129.89 ? 232 HIS C N   1 -0.357 0.012  0.129  
ATOM   7994  C  CA  . HIS C 1 243 ? -38.746 1.047   53.154  1    124.33 ? 232 HIS C CA  1 -0.355 0.01   0.133  
ATOM   7995  C  C   . HIS C 1 243 ? -37.747 2.005   53.773  1    127.03 ? 232 HIS C C   1 -0.346 0.018  0.134  
ATOM   7996  O  O   . HIS C 1 243 ? -38.07  2.733   54.718  1    133.97 ? 232 HIS C O   1 -0.349 0.025  0.137  
ATOM   7997  C  CB  . HIS C 1 243 ? -38.29  -0.389  53.419  1    121.56 ? 232 HIS C CB  1 -0.351 -0.004 0.133  
ATOM   7998  C  CG  . HIS C 1 243 ? -39.393 -1.395  53.366  1    133.28 ? 232 HIS C CG  1 -0.361 -0.013 0.133  
ATOM   7999  N  ND1 . HIS C 1 243 ? -40.726 -1.036  53.382  1    136.45 ? 232 HIS C ND1 1 -0.373 -0.009 0.133  
ATOM   8000  C  CD2 . HIS C 1 243 ? -39.366 -2.747  53.286  1    132.55 ? 232 HIS C CD2 1 -0.361 -0.025 0.133  
ATOM   8001  C  CE1 . HIS C 1 243 ? -41.472 -2.125  53.325  1    139.76 ? 232 HIS C CE1 1 -0.38  -0.019 0.133  
ATOM   8002  N  NE2 . HIS C 1 243 ? -40.672 -3.176  53.26   1    138.19 ? 232 HIS C NE2 1 -0.373 -0.029 0.133  
ATOM   8003  N  N   . SER C 1 244 ? -36.516 2.004   53.259  1    123.95 ? 233 SER C N   1 -0.335 0.018  0.133  
ATOM   8004  C  CA  . SER C 1 244 ? -35.381 2.549   53.983  1    124.27 ? 233 SER C CA  1 -0.324 0.023  0.135  
ATOM   8005  C  C   . SER C 1 244 ? -34.779 3.795   53.356  1    120.71 ? 233 SER C C   1 -0.319 0.035  0.133  
ATOM   8006  O  O   . SER C 1 244 ? -33.916 4.422   53.982  1    123.1  ? 233 SER C O   1 -0.311 0.041  0.135  
ATOM   8007  C  CB  . SER C 1 244 ? -34.28  1.481   54.125  1    124.07 ? 233 SER C CB  1 -0.314 0.014  0.135  
ATOM   8008  O  OG  . SER C 1 244 ? -34.816 0.231   54.537  1    123.81 ? 233 SER C OG  1 -0.319 0.002  0.136  
ATOM   8009  N  N   . PHE C 1 245 ? -35.189 4.172   52.151  1    124.1  ? 234 PHE C N   1 -0.322 0.038  0.13   
ATOM   8010  C  CA  . PHE C 1 245 ? -34.592 5.309   51.474  1    122.98 ? 234 PHE C CA  1 -0.317 0.049  0.129  
ATOM   8011  C  C   . PHE C 1 245 ? -35.571 6.44    51.192  1    123.23 ? 234 PHE C C   1 -0.326 0.059  0.128  
ATOM   8012  O  O   . PHE C 1 245 ? -35.124 7.548   50.867  1    120.88 ? 234 PHE C O   1 -0.322 0.069  0.127  
ATOM   8013  C  CB  . PHE C 1 245 ? -33.944 4.859   50.154  1    117.56 ? 234 PHE C CB  1 -0.311 0.045  0.125  
ATOM   8014  C  CG  . PHE C 1 245 ? -32.707 4.012   50.33   1    116.95 ? 234 PHE C CG  1 -0.3   0.037  0.126  
ATOM   8015  C  CD1 . PHE C 1 245 ? -32.798 2.709   50.805  1    117.88 ? 234 PHE C CD1 1 -0.301 0.025  0.127  
ATOM   8016  C  CD2 . PHE C 1 245 ? -31.452 4.511   49.997  1    113.93 ? 234 PHE C CD2 1 -0.288 0.041  0.125  
ATOM   8017  C  CE1 . PHE C 1 245 ? -31.66  1.919   50.961  1    113.19 ? 234 PHE C CE1 1 -0.29  0.018  0.127  
ATOM   8018  C  CE2 . PHE C 1 245 ? -30.308 3.729   50.149  1    110.52 ? 234 PHE C CE2 1 -0.278 0.034  0.125  
ATOM   8019  C  CZ  . PHE C 1 245 ? -30.414 2.432   50.634  1    109.7  ? 234 PHE C CZ  1 -0.279 0.022  0.126  
ATOM   8020  N  N   . SER C 1 246 ? -36.882 6.207   51.354  1    124.47 ? 235 SER C N   1 -0.338 0.057  0.128  
ATOM   8021  C  CA  . SER C 1 246 ? -37.907 7.157   50.917  1    123.14 ? 235 SER C CA  1 -0.347 0.066  0.127  
ATOM   8022  C  C   . SER C 1 246 ? -37.725 8.557   51.496  1    124.57 ? 235 SER C C   1 -0.346 0.078  0.129  
ATOM   8023  O  O   . SER C 1 246 ? -38.347 9.498   50.99   1    122.8  ? 235 SER C O   1 -0.351 0.087  0.127  
ATOM   8024  C  CB  . SER C 1 246 ? -39.308 6.625   51.261  1    124.01 ? 235 SER C CB  1 -0.36  0.061  0.128  
ATOM   8025  O  OG  . SER C 1 246 ? -39.412 6.203   52.607  1    120.91 ? 235 SER C OG  1 -0.361 0.057  0.131  
ATOM   8026  N  N   . HIS C 1 247 ? -36.893 8.722   52.533  1    127.99 ? 236 HIS C N   1 -0.338 0.08   0.131  
ATOM   8027  C  CA  . HIS C 1 247 ? -36.585 10.062  53.028  1    127.66 ? 236 HIS C CA  1 -0.335 0.092  0.132  
ATOM   8028  C  C   . HIS C 1 247 ? -35.688 10.835  52.067  1    124.53 ? 236 HIS C C   1 -0.327 0.099  0.13   
ATOM   8029  O  O   . HIS C 1 247 ? -35.717 12.072  52.062  1    121.54 ? 236 HIS C O   1 -0.327 0.111  0.13   
ATOM   8030  C  CB  . HIS C 1 247 ? -35.95  9.99    54.43   1    131.61 ? 236 HIS C CB  1 -0.329 0.092  0.136  
ATOM   8031  C  CG  . HIS C 1 247 ? -34.615 9.299   54.486  1    130.08 ? 236 HIS C CG  1 -0.317 0.085  0.136  
ATOM   8032  N  ND1 . HIS C 1 247 ? -34.464 7.941   54.293  1    127.87 ? 236 HIS C ND1 1 -0.316 0.073  0.136  
ATOM   8033  C  CD2 . HIS C 1 247 ? -33.377 9.777   54.771  1    127.72 ? 236 HIS C CD2 1 -0.306 0.09   0.137  
ATOM   8034  C  CE1 . HIS C 1 247 ? -33.187 7.618   54.428  1    128.49 ? 236 HIS C CE1 1 -0.304 0.07   0.136  
ATOM   8035  N  NE2 . HIS C 1 247 ? -32.506 8.714   54.716  1    124.02 ? 236 HIS C NE2 1 -0.298 0.08   0.137  
ATOM   8036  N  N   . LEU C 1 248 ? -34.917 10.14   51.241  1    124.2  ? 237 LEU C N   1 -0.32  0.093  0.128  
ATOM   8037  C  CA  . LEU C 1 248 ? -34.08  10.798  50.25   1    125.98 ? 237 LEU C CA  1 -0.312 0.099  0.125  
ATOM   8038  C  C   . LEU C 1 248 ? -34.9   11.209  49.026  1    126.46 ? 237 LEU C C   1 -0.32  0.103  0.122  
ATOM   8039  O  O   . LEU C 1 248 ? -35.82  10.5    48.603  1    123    ? 237 LEU C O   1 -0.328 0.096  0.121  
ATOM   8040  C  CB  . LEU C 1 248 ? -32.94  9.865   49.848  1    122.33 ? 237 LEU C CB  1 -0.302 0.09   0.124  
ATOM   8041  C  CG  . LEU C 1 248 ? -31.765 9.796   50.819  1    116.51 ? 237 LEU C CG  1 -0.291 0.09   0.127  
ATOM   8042  C  CD1 . LEU C 1 248 ? -30.858 8.628   50.503  1    112.93 ? 237 LEU C CD1 1 -0.283 0.079  0.126  
ATOM   8043  C  CD2 . LEU C 1 248 ? -30.993 11.092  50.737  1    123.38 ? 237 LEU C CD2 1 -0.284 0.102  0.127  
ATOM   8044  N  N   . SER C 1 249 ? -34.574 12.372  48.464  1    123.8  ? 238 SER C N   1 -0.317 0.113  0.121  
ATOM   8045  C  CA  . SER C 1 249 ? -35.254 12.833  47.257  1    127.48 ? 238 SER C CA  1 -0.323 0.118  0.118  
ATOM   8046  C  C   . SER C 1 249 ? -34.864 11.936  46.088  1    130.74 ? 238 SER C C   1 -0.319 0.109  0.115  
ATOM   8047  O  O   . SER C 1 249 ? -33.678 11.825  45.754  1    132.83 ? 238 SER C O   1 -0.309 0.108  0.114  
ATOM   8048  C  CB  . SER C 1 249 ? -34.901 14.293  46.973  1    132.66 ? 238 SER C CB  1 -0.32  0.131  0.117  
ATOM   8049  O  OG  . SER C 1 249 ? -33.539 14.565  47.275  1    137.09 ? 238 SER C OG  1 -0.307 0.133  0.118  
ATOM   8050  N  N   . ILE C 1 250 ? -35.852 11.283  45.474  1    127.26 ? 239 ILE C N   1 -0.329 0.103  0.114  
ATOM   8051  C  CA  . ILE C 1 250 ? -35.588 10.225  44.498  1    123.76 ? 239 ILE C CA  1 -0.326 0.094  0.111  
ATOM   8052  C  C   . ILE C 1 250 ? -36.681 10.222  43.445  1    126.05 ? 239 ILE C C   1 -0.336 0.094  0.108  
ATOM   8053  O  O   . ILE C 1 250 ? -37.871 10.142  43.766  1    121.36 ? 239 ILE C O   1 -0.347 0.093  0.109  
ATOM   8054  C  CB  . ILE C 1 250 ? -35.496 8.833   45.159  1    123.17 ? 239 ILE C CB  1 -0.325 0.081  0.113  
ATOM   8055  C  CG1 . ILE C 1 250 ? -34.095 8.579   45.707  1    127.84 ? 239 ILE C CG1 1 -0.312 0.079  0.114  
ATOM   8056  C  CG2 . ILE C 1 250 ? -35.854 7.745   44.185  1    117.77 ? 239 ILE C CG2 1 -0.329 0.071  0.11   
ATOM   8057  C  CD1 . ILE C 1 250 ? -33.868 7.154   46.098  1    130.8  ? 239 ILE C CD1 1 -0.31  0.066  0.115  
ATOM   8058  N  N   . CYS C 1 251 ? -36.26  10.296  42.186  1    120.8  ? 240 CYS C N   1 -0.332 0.094  0.105  
ATOM   8059  C  CA  . CYS C 1 251 ? -37.1   10.022  41.032  1    116.19 ? 240 CYS C CA  1 -0.34  0.092  0.102  
ATOM   8060  C  C   . CYS C 1 251 ? -36.684 8.659   40.488  1    116.1  ? 240 CYS C C   1 -0.336 0.079  0.101  
ATOM   8061  O  O   . CYS C 1 251 ? -35.503 8.435   40.207  1    117.68 ? 240 CYS C O   1 -0.325 0.077  0.1    
ATOM   8062  C  CB  . CYS C 1 251 ? -36.932 11.12   39.984  1    125.92 ? 240 CYS C CB  1 -0.338 0.102  0.1    
ATOM   8063  S  SG  . CYS C 1 251 ? -38.343 11.438  38.904  1    142.45 ? 240 CYS C SG  1 -0.351 0.105  0.097  
ATOM   8064  N  N   . HIS C 1 252 ? -37.644 7.749   40.353  1    114.96 ? 241 HIS C N   1 -0.345 0.071  0.101  
ATOM   8065  C  CA  . HIS C 1 252 ? -37.361 6.364   39.987  1    115.62 ? 241 HIS C CA  1 -0.342 0.058  0.1    
ATOM   8066  C  C   . HIS C 1 252 ? -38.244 5.975   38.801  1    118.44 ? 241 HIS C C   1 -0.35  0.055  0.097  
ATOM   8067  O  O   . HIS C 1 252 ? -39.463 5.809   38.952  1    112.82 ? 241 HIS C O   1 -0.362 0.053  0.097  
ATOM   8068  C  CB  . HIS C 1 252 ? -37.58  5.443   41.189  1    114.84 ? 241 HIS C CB  1 -0.344 0.05   0.103  
ATOM   8069  C  CG  . HIS C 1 252 ? -37.248 4.008   40.933  1    120.83 ? 241 HIS C CG  1 -0.341 0.037  0.102  
ATOM   8070  N  ND1 . HIS C 1 252 ? -36.427 3.603   39.903  1    126.36 ? 241 HIS C ND1 1 -0.334 0.033  0.1    
ATOM   8071  C  CD2 . HIS C 1 252 ? -37.634 2.878   41.572  1    124.2  ? 241 HIS C CD2 1 -0.345 0.026  0.104  
ATOM   8072  C  CE1 . HIS C 1 252 ? -36.327 2.284   39.914  1    126.52 ? 241 HIS C CE1 1 -0.333 0.021  0.1    
ATOM   8073  N  NE2 . HIS C 1 252 ? -37.052 1.818   40.918  1    123.92 ? 241 HIS C NE2 1 -0.34  0.017  0.102  
ATOM   8074  N  N   . ILE C 1 253 ? -37.623 5.835   37.622  1    117.69 ? 242 ILE C N   1 -0.345 0.053  0.094  
ATOM   8075  C  CA  . ILE C 1 253 ? -38.312 5.575   36.356  1    111.88 ? 242 ILE C CA  1 -0.351 0.051  0.091  
ATOM   8076  C  C   . ILE C 1 253 ? -38.07  4.115   35.991  1    108.25 ? 242 ILE C C   1 -0.349 0.038  0.09   
ATOM   8077  O  O   . ILE C 1 253 ? -36.951 3.732   35.618  1    107.52 ? 242 ILE C O   1 -0.339 0.034  0.089  
ATOM   8078  C  CB  . ILE C 1 253 ? -37.834 6.527   35.248  1    110.52 ? 242 ILE C CB  1 -0.347 0.06   0.088  
ATOM   8079  C  CG1 . ILE C 1 253 ? -38.452 7.917   35.427  1    108.6  ? 242 ILE C CG1 1 -0.352 0.073  0.088  
ATOM   8080  C  CG2 . ILE C 1 253 ? -38.151 5.981   33.852  1    118.12 ? 242 ILE C CG2 1 -0.35  0.055  0.085  
ATOM   8081  C  CD1 . ILE C 1 253 ? -37.676 8.818   36.368  1    118.11 ? 242 ILE C CD1 1 -0.345 0.081  0.091  
ATOM   8082  N  N   . ASP C 1 254 ? -39.119 3.294   36.101  1    104.36 ? 243 ASP C N   1 -0.358 0.03   0.09   
ATOM   8083  C  CA  . ASP C 1 254 ? -39.02  1.845   35.938  1    107.73 ? 243 ASP C CA  1 -0.358 0.017  0.09   
ATOM   8084  C  C   . ASP C 1 254 ? -39.74  1.444   34.656  1    116.57 ? 243 ASP C C   1 -0.364 0.013  0.087  
ATOM   8085  O  O   . ASP C 1 254 ? -40.971 1.538   34.556  1    116.29 ? 243 ASP C O   1 -0.375 0.014  0.086  
ATOM   8086  C  CB  . ASP C 1 254 ? -39.591 1.108   37.149  1    115.49 ? 243 ASP C CB  1 -0.363 0.01   0.093  
ATOM   8087  C  CG  . ASP C 1 254 ? -39.375 -0.414  37.09   1    113.97 ? 243 ASP C CG  1 -0.361 -0.004 0.093  
ATOM   8088  O  OD1 . ASP C 1 254 ? -39.377 -1.004  35.989  1    119.91 ? 243 ASP C OD1 1 -0.361 -0.009 0.09   
ATOM   8089  O  OD2 . ASP C 1 254 ? -39.203 -1.034  38.159  1    114.33 ? 243 ASP C OD2 1 -0.359 -0.009 0.095  
ATOM   8090  N  N   . VAL C 1 255 ? -38.967 0.968   33.694  1    115.81 ? 244 VAL C N   1 -0.357 0.009  0.084  
ATOM   8091  C  CA  . VAL C 1 255 ? -39.46  0.556   32.394  1    111.42 ? 244 VAL C CA  1 -0.362 0.005  0.081  
ATOM   8092  C  C   . VAL C 1 255 ? -39.444 -0.964  32.396  1    112.44 ? 244 VAL C C   1 -0.361 -0.009 0.081  
ATOM   8093  O  O   . VAL C 1 255 ? -38.391 -1.576  32.613  1    114.55 ? 244 VAL C O   1 -0.352 -0.014 0.081  
ATOM   8094  C  CB  . VAL C 1 255 ? -38.588 1.151   31.277  1    109.27 ? 244 VAL C CB  1 -0.354 0.011  0.078  
ATOM   8095  C  CG1 . VAL C 1 255 ? -39.059 0.703   29.917  1    108.89 ? 244 VAL C CG1 1 -0.358 0.006  0.075  
ATOM   8096  C  CG2 . VAL C 1 255 ? -38.601 2.661   31.4    1    103.34 ? 244 VAL C CG2 1 -0.354 0.024  0.078  
ATOM   8097  N  N   . PHE C 1 256 ? -40.61  -1.576  32.213  1    107.99 ? 245 PHE C N   1 -0.372 -0.014 0.08   
ATOM   8098  C  CA  . PHE C 1 256 ? -40.71  -3.024  32.348  1    109.97 ? 245 PHE C CA  1 -0.373 -0.028 0.081  
ATOM   8099  C  C   . PHE C 1 256 ? -41.963 -3.481  31.628  1    107.21 ? 245 PHE C C   1 -0.385 -0.032 0.079  
ATOM   8100  O  O   . PHE C 1 256 ? -42.876 -2.689  31.383  1    110.43 ? 245 PHE C O   1 -0.393 -0.025 0.078  
ATOM   8101  C  CB  . PHE C 1 256 ? -40.749 -3.464  33.824  1    116.16 ? 245 PHE C CB  1 -0.373 -0.032 0.084  
ATOM   8102  C  CG  . PHE C 1 256 ? -42.06  -3.166  34.522  1    110.69 ? 245 PHE C CG  1 -0.385 -0.029 0.086  
ATOM   8103  C  CD1 . PHE C 1 256 ? -43.099 -4.081  34.483  1    111.67 ? 245 PHE C CD1 1 -0.395 -0.037 0.086  
ATOM   8104  C  CD2 . PHE C 1 256 ? -42.26  -1.967  35.209  1    112.72 ? 245 PHE C CD2 1 -0.387 -0.018 0.088  
ATOM   8105  C  CE1 . PHE C 1 256 ? -44.311 -3.815  35.112  1    118.53 ? 245 PHE C CE1 1 -0.406 -0.035 0.088  
ATOM   8106  C  CE2 . PHE C 1 256 ? -43.481 -1.694  35.849  1    115.13 ? 245 PHE C CE2 1 -0.398 -0.016 0.09   
ATOM   8107  C  CZ  . PHE C 1 256 ? -44.502 -2.624  35.798  1    116.76 ? 245 PHE C CZ  1 -0.408 -0.024 0.089  
ATOM   8108  N  N   . ASP C 1 257 ? -41.994 -4.765  31.297  1    107.26 ? 246 ASP C N   1 -0.385 -0.044 0.078  
ATOM   8109  C  CA  . ASP C 1 257 ? -43.149 -5.386  30.654  1    115    ? 246 ASP C CA  1 -0.395 -0.049 0.077  
ATOM   8110  C  C   . ASP C 1 257 ? -43.941 -6.16   31.711  1    113.14 ? 246 ASP C C   1 -0.403 -0.056 0.079  
ATOM   8111  O  O   . ASP C 1 257 ? -43.477 -7.185  32.223  1    109.62 ? 246 ASP C O   1 -0.398 -0.066 0.08   
ATOM   8112  C  CB  . ASP C 1 257 ? -42.701 -6.285  29.499  1    113.16 ? 246 ASP C CB  1 -0.391 -0.058 0.074  
ATOM   8113  C  CG  . ASP C 1 257 ? -43.841 -6.68   28.56   1    116.17 ? 246 ASP C CG  1 -0.402 -0.061 0.071  
ATOM   8114  O  OD1 . ASP C 1 257 ? -44.894 -7.134  29.053  1    113.03 ? 246 ASP C OD1 1 -0.411 -0.065 0.073  
ATOM   8115  O  OD2 . ASP C 1 257 ? -43.679 -6.556  27.317  1    125.99 ? 246 ASP C OD2 1 -0.4   -0.06  0.068  
ATOM   8116  N  N   . SER C 1 258 ? -45.153 -5.679  32.01   1    109.16 ? 247 SER C N   1 -0.414 -0.052 0.08   
ATOM   8117  C  CA  . SER C 1 258 ? -46.046 -6.278  32.996  1    115.39 ? 247 SER C CA  1 -0.422 -0.058 0.082  
ATOM   8118  C  C   . SER C 1 258 ? -46.518 -7.684  32.63   1    117.23 ? 247 SER C C   1 -0.426 -0.07  0.081  
ATOM   8119  O  O   . SER C 1 258 ? -47.268 -8.28   33.411  1    124.14 ? 247 SER C O   1 -0.433 -0.076 0.083  
ATOM   8120  C  CB  . SER C 1 258 ? -47.265 -5.376  33.21   1    118.51 ? 247 SER C CB  1 -0.433 -0.049 0.083  
ATOM   8121  O  OG  . SER C 1 258 ? -48.135 -5.415  32.094  1    116.86 ? 247 SER C OG  1 -0.441 -0.05  0.08   
ATOM   8122  N  N   . ARG C 1 259 ? -46.117 -8.236  31.487  1    116.79 ? 248 ARG C N   1 -0.423 -0.075 0.079  
ATOM   8123  C  CA  . ARG C 1 259 ? -46.55  -9.57   31.099  1    115.74 ? 248 ARG C CA  1 -0.427 -0.088 0.078  
ATOM   8124  C  C   . ARG C 1 259 ? -45.442 -10.604 31.192  1    116.16 ? 248 ARG C C   1 -0.416 -0.097 0.078  
ATOM   8125  O  O   . ARG C 1 259 ? -45.736 -11.804 31.163  1    115.7  ? 248 ARG C O   1 -0.419 -0.108 0.078  
ATOM   8126  C  CB  . ARG C 1 259 ? -47.124 -9.551  29.674  1    119.88 ? 248 ARG C CB  1 -0.432 -0.088 0.074  
ATOM   8127  C  CG  . ARG C 1 259 ? -47.847 -8.247  29.367  1    121.14 ? 248 ARG C CG  1 -0.438 -0.076 0.073  
ATOM   8128  C  CD  . ARG C 1 259 ? -48.812 -8.277  28.182  1    120.09 ? 248 ARG C CD  1 -0.447 -0.076 0.07   
ATOM   8129  N  NE  . ARG C 1 259 ? -48.182 -8.572  26.901  1    124.88 ? 248 ARG C NE  1 -0.442 -0.079 0.067  
ATOM   8130  C  CZ  . ARG C 1 259 ? -47.241 -7.846  26.305  1    125.85 ? 248 ARG C CZ  1 -0.433 -0.072 0.066  
ATOM   8131  N  NH1 . ARG C 1 259 ? -46.723 -6.767  26.87   1    124.63 ? 248 ARG C NH1 1 -0.428 -0.062 0.067  
ATOM   8132  N  NH2 . ARG C 1 259 ? -46.802 -8.217  25.109  1    125.93 ? 248 ARG C NH2 1 -0.429 -0.075 0.063  
ATOM   8133  N  N   . VAL C 1 260 ? -44.187 -10.171 31.307  1    115.28 ? 249 VAL C N   1 -0.405 -0.093 0.078  
ATOM   8134  C  CA  . VAL C 1 260 ? -43.082 -11.078 31.591  1    118.24 ? 249 VAL C CA  1 -0.395 -0.102 0.079  
ATOM   8135  C  C   . VAL C 1 260 ? -42.697 -10.894 33.053  1    118.84 ? 249 VAL C C   1 -0.391 -0.1   0.083  
ATOM   8136  O  O   . VAL C 1 260 ? -43.318 -10.106 33.775  1    114.31 ? 249 VAL C O   1 -0.397 -0.093 0.084  
ATOM   8137  C  CB  . VAL C 1 260 ? -41.885 -10.837 30.648  1    110.56 ? 249 VAL C CB  1 -0.384 -0.099 0.077  
ATOM   8138  C  CG1 . VAL C 1 260 ? -42.345 -10.859 29.192  1    120.42 ? 249 VAL C CG1 1 -0.388 -0.1   0.073  
ATOM   8139  C  CG2 . VAL C 1 260 ? -41.193 -9.529  30.985  1    107.11 ? 249 VAL C CG2 1 -0.377 -0.087 0.077  
ATOM   8140  N  N   . TYR C 1 261 ? -41.678 -11.622 33.491  1    114.39 ? 250 TYR C N   1 -0.382 -0.107 0.084  
ATOM   8141  C  CA  . TYR C 1 261 ? -41.268 -11.625 34.886  1    114.61 ? 250 TYR C CA  1 -0.378 -0.107 0.087  
ATOM   8142  C  C   . TYR C 1 261 ? -41.097 -10.194 35.405  1    121.39 ? 250 TYR C C   1 -0.377 -0.093 0.088  
ATOM   8143  O  O   . TYR C 1 261 ? -40.662 -9.311  34.648  1    117.63 ? 250 TYR C O   1 -0.373 -0.085 0.087  
ATOM   8144  C  CB  . TYR C 1 261 ? -39.962 -12.403 35.017  1    116.62 ? 250 TYR C CB  1 -0.366 -0.114 0.087  
ATOM   8145  C  CG  . TYR C 1 261 ? -39.511 -12.684 36.424  1    115.6  ? 250 TYR C CG  1 -0.362 -0.116 0.091  
ATOM   8146  C  CD1 . TYR C 1 261 ? -38.767 -11.75  37.132  1    114.66 ? 250 TYR C CD1 1 -0.355 -0.108 0.093  
ATOM   8147  C  CD2 . TYR C 1 261 ? -39.8   -13.899 37.031  1    116.26 ? 250 TYR C CD2 1 -0.365 -0.127 0.092  
ATOM   8148  C  CE1 . TYR C 1 261 ? -38.334 -12.01  38.413  1    120.33 ? 250 TYR C CE1 1 -0.351 -0.11  0.096  
ATOM   8149  C  CE2 . TYR C 1 261 ? -39.371 -14.177 38.313  1    118.2  ? 250 TYR C CE2 1 -0.361 -0.13  0.096  
ATOM   8150  C  CZ  . TYR C 1 261 ? -38.638 -13.225 39.008  1    123.08 ? 250 TYR C CZ  1 -0.354 -0.121 0.097  
ATOM   8151  O  OH  . TYR C 1 261 ? -38.2   -13.476 40.297  1    115.22 ? 250 TYR C OH  1 -0.35  -0.123 0.101  
ATOM   8152  N  N   . PRO C 1 262 ? -41.479 -9.908  36.681  1    124.04 ? 251 PRO C N   1 -0.38  -0.091 0.092  
ATOM   8153  C  CA  . PRO C 1 262 ? -42.259 -10.739 37.621  1    117.87 ? 251 PRO C CA  1 -0.387 -0.098 0.094  
ATOM   8154  C  C   . PRO C 1 262 ? -43.757 -10.404 37.646  1    117.21 ? 251 PRO C C   1 -0.401 -0.095 0.094  
ATOM   8155  O  O   . PRO C 1 262 ? -44.282 -10.029 38.676  1    120.23 ? 251 PRO C O   1 -0.406 -0.092 0.097  
ATOM   8156  C  CB  . PRO C 1 262 ? -41.598 -10.416 38.96   1    115.26 ? 251 PRO C CB  1 -0.381 -0.095 0.097  
ATOM   8157  C  CG  . PRO C 1 262 ? -41.311 -8.949  38.837  1    116.84 ? 251 PRO C CG  1 -0.379 -0.082 0.097  
ATOM   8158  C  CD  . PRO C 1 262 ? -40.878 -8.759  37.387  1    119.54 ? 251 PRO C CD  1 -0.375 -0.08  0.093  
ATOM   8159  N  N   . GLN C 1 263 ? -44.44  -10.504 36.505  1    124.16 ? 252 GLN C N   1 -0.407 -0.096 0.091  
ATOM   8160  C  CA  . GLN C 1 263 ? -45.894 -10.407 36.339  1    124.01 ? 252 GLN C CA  1 -0.421 -0.095 0.091  
ATOM   8161  C  C   . GLN C 1 263 ? -46.616 -9.443  37.274  1    121.72 ? 252 GLN C C   1 -0.427 -0.087 0.093  
ATOM   8162  O  O   . GLN C 1 263 ? -47.812 -9.615  37.533  1    123.81 ? 252 GLN C O   1 -0.438 -0.088 0.094  
ATOM   8163  C  CB  . GLN C 1 263 ? -46.511 -11.802 36.473  1    129.03 ? 252 GLN C CB  1 -0.426 -0.108 0.091  
ATOM   8164  C  CG  . GLN C 1 263 ? -46.568 -12.609 35.149  1    123.37 ? 252 GLN C CG  1 -0.427 -0.116 0.088  
ATOM   8165  C  CD  . GLN C 1 263 ? -45.199 -13.086 34.678  1    130.48 ? 252 GLN C CD  1 -0.414 -0.12  0.087  
ATOM   8166  O  OE1 . GLN C 1 263 ? -44.155 -12.648 35.194  1    131.55 ? 252 GLN C OE1 1 -0.405 -0.116 0.088  
ATOM   8167  N  NE2 . GLN C 1 263 ? -45.194 -13.999 33.692  1    123.57 ? 252 GLN C NE2 1 -0.414 -0.128 0.084  
ATOM   8168  N  N   . GLN C 1 264 ? -45.925 -8.416  37.756  1    121.66 ? 253 GLN C N   1 -0.421 -0.077 0.094  
ATOM   8169  C  CA  . GLN C 1 264 ? -46.527 -7.438  38.66   1    123.99 ? 253 GLN C CA  1 -0.426 -0.068 0.097  
ATOM   8170  C  C   . GLN C 1 264 ? -47.053 -6.265  37.831  1    125.32 ? 253 GLN C C   1 -0.431 -0.057 0.094  
ATOM   8171  O  O   . GLN C 1 264 ? -46.305 -5.344  37.483  1    126.51 ? 253 GLN C O   1 -0.424 -0.049 0.094  
ATOM   8172  C  CB  . GLN C 1 264 ? -45.523 -7.012  39.727  1    120.09 ? 253 GLN C CB  1 -0.417 -0.064 0.099  
ATOM   8173  C  CG  . GLN C 1 264 ? -45.342 -8.081  40.808  1    120.61 ? 253 GLN C CG  1 -0.416 -0.074 0.102  
ATOM   8174  C  CD  . GLN C 1 264 ? -43.902 -8.262  41.29   1    123.25 ? 253 GLN C CD  1 -0.402 -0.076 0.103  
ATOM   8175  O  OE1 . GLN C 1 264 ? -43.113 -7.313  41.327  1    125.27 ? 253 GLN C OE1 1 -0.395 -0.067 0.103  
ATOM   8176  N  NE2 . GLN C 1 264 ? -43.56  -9.493  41.671  1    119.29 ? 253 GLN C NE2 1 -0.399 -0.087 0.104  
ATOM   8177  N  N   . ASP C 1 265 ? -48.348 -6.31   37.516  1    120.48 ? 254 ASP C N   1 -0.443 -0.058 0.094  
ATOM   8178  C  CA  . ASP C 1 265 ? -49.026 -5.242  36.799  1    118.37 ? 254 ASP C CA  1 -0.449 -0.048 0.092  
ATOM   8179  C  C   . ASP C 1 265 ? -49.411 -4.104  37.749  1    119.8  ? 254 ASP C C   1 -0.453 -0.038 0.094  
ATOM   8180  O  O   . ASP C 1 265 ? -49.185 -4.158  38.962  1    123.23 ? 254 ASP C O   1 -0.451 -0.038 0.097  
ATOM   8181  C  CB  . ASP C 1 265 ? -50.252 -5.786  36.076  1    119.1  ? 254 ASP C CB  1 -0.461 -0.053 0.09   
ATOM   8182  C  CG  . ASP C 1 265 ? -51.443 -5.894  36.977  1    122.38 ? 254 ASP C CG  1 -0.471 -0.054 0.092  
ATOM   8183  O  OD1 . ASP C 1 265 ? -51.24  -6.313  38.133  1    130.95 ? 254 ASP C OD1 1 -0.47  -0.058 0.095  
ATOM   8184  O  OD2 . ASP C 1 265 ? -52.566 -5.55   36.554  1    119.9  ? 254 ASP C OD2 1 -0.482 -0.051 0.091  
ATOM   8185  N  N   . PHE C 1 266 ? -50.019 -3.061  37.183  1    125.12 ? 255 PHE C N   1 -0.458 -0.028 0.093  
ATOM   8186  C  CA  . PHE C 1 266 ? -50.311 -1.85   37.948  1    130.55 ? 255 PHE C CA  1 -0.461 -0.017 0.095  
ATOM   8187  C  C   . PHE C 1 266 ? -51.09  -2.131  39.224  1    126.61 ? 255 PHE C C   1 -0.468 -0.02  0.098  
ATOM   8188  O  O   . PHE C 1 266 ? -50.946 -1.397  40.21   1    124.91 ? 255 PHE C O   1 -0.467 -0.013 0.1    
ATOM   8189  C  CB  . PHE C 1 266 ? -51.085 -0.848  37.083  1    130.68 ? 255 PHE C CB  1 -0.468 -0.008 0.093  
ATOM   8190  C  CG  . PHE C 1 266 ? -50.225 -0.122  36.11   1    130.18 ? 255 PHE C CG  1 -0.46  -0.001 0.09   
ATOM   8191  C  CD1 . PHE C 1 266 ? -49.487 0.977   36.512  1    132.72 ? 255 PHE C CD1 1 -0.454 0.009  0.091  
ATOM   8192  C  CD2 . PHE C 1 266 ? -50.124 -0.549  34.8    1    125.36 ? 255 PHE C CD2 1 -0.459 -0.005 0.087  
ATOM   8193  C  CE1 . PHE C 1 266 ? -48.668 1.651   35.619  1    131.68 ? 255 PHE C CE1 1 -0.446 0.015  0.089  
ATOM   8194  C  CE2 . PHE C 1 266 ? -49.309 0.126   33.903  1    128.49 ? 255 PHE C CE2 1 -0.452 0.001  0.085  
ATOM   8195  C  CZ  . PHE C 1 266 ? -48.582 1.23    34.315  1    125.53 ? 255 PHE C CZ  1 -0.445 0.011  0.086  
ATOM   8196  N  N   . ALA C 1 267 ? -51.916 -3.184  39.222  1    125.55 ? 256 ALA C N   1 -0.476 -0.029 0.098  
ATOM   8197  C  CA  . ALA C 1 267 ? -52.661 -3.561  40.419  1    128.13 ? 256 ALA C CA  1 -0.483 -0.033 0.101  
ATOM   8198  C  C   . ALA C 1 267 ? -51.716 -3.868  41.58   1    127.53 ? 256 ALA C C   1 -0.474 -0.035 0.104  
ATOM   8199  O  O   . ALA C 1 267 ? -51.806 -3.258  42.649  1    124.59 ? 256 ALA C O   1 -0.475 -0.03  0.106  
ATOM   8200  C  CB  . ALA C 1 267 ? -53.56  -4.762  40.115  1    118.69 ? 256 ALA C CB  1 -0.491 -0.044 0.1    
ATOM   8201  N  N   . TYR C 1 268 ? -50.785 -4.8    41.368  1    126.47 ? 257 TYR C N   1 -0.465 -0.044 0.103  
ATOM   8202  C  CA  . TYR C 1 268 ? -49.875 -5.242  42.42   1    122.71 ? 257 TYR C CA  1 -0.457 -0.048 0.106  
ATOM   8203  C  C   . TYR C 1 268 ? -49.146 -4.074  43.084  1    127.59 ? 257 TYR C C   1 -0.45  -0.037 0.108  
ATOM   8204  O  O   . TYR C 1 268 ? -48.943 -4.085  44.304  1    132.35 ? 257 TYR C O   1 -0.449 -0.037 0.111  
ATOM   8205  C  CB  . TYR C 1 268 ? -48.885 -6.246  41.827  1    123.22 ? 257 TYR C CB  1 -0.448 -0.057 0.104  
ATOM   8206  C  CG  . TYR C 1 268 ? -47.925 -6.929  42.786  1    123.28 ? 257 TYR C CG  1 -0.439 -0.063 0.107  
ATOM   8207  C  CD1 . TYR C 1 268 ? -46.805 -6.263  43.281  1    124.67 ? 257 TYR C CD1 1 -0.429 -0.057 0.108  
ATOM   8208  C  CD2 . TYR C 1 268 ? -48.097 -8.262  43.138  1    119.63 ? 257 TYR C CD2 1 -0.441 -0.076 0.108  
ATOM   8209  C  CE1 . TYR C 1 268 ? -45.903 -6.895  44.122  1    122.02 ? 257 TYR C CE1 1 -0.421 -0.063 0.11   
ATOM   8210  C  CE2 . TYR C 1 268 ? -47.198 -8.902  43.984  1    121.6  ? 257 TYR C CE2 1 -0.433 -0.082 0.11   
ATOM   8211  C  CZ  . TYR C 1 268 ? -46.106 -8.209  44.473  1    122.04 ? 257 TYR C CZ  1 -0.423 -0.075 0.111  
ATOM   8212  O  OH  . TYR C 1 268 ? -45.208 -8.826  45.312  1    124.44 ? 257 TYR C OH  1 -0.414 -0.081 0.113  
ATOM   8213  N  N   . ILE C 1 269 ? -48.735 -3.059  42.316  1    128.92 ? 258 ILE C N   1 -0.447 -0.028 0.106  
ATOM   8214  C  CA  . ILE C 1 269 ? -47.987 -1.966  42.945  1    132.16 ? 258 ILE C CA  1 -0.44  -0.018 0.107  
ATOM   8215  C  C   . ILE C 1 269 ? -48.894 -1.129  43.846  1    134.7  ? 258 ILE C C   1 -0.448 -0.01  0.109  
ATOM   8216  O  O   . ILE C 1 269 ? -48.406 -0.454  44.762  1    133.26 ? 258 ILE C O   1 -0.444 -0.004 0.112  
ATOM   8217  C  CB  . ILE C 1 269 ? -47.269 -1.078  41.901  1    128.49 ? 258 ILE C CB  1 -0.433 -0.01  0.105  
ATOM   8218  C  CG1 . ILE C 1 269 ? -46.535 -1.924  40.857  1    123.94 ? 258 ILE C CG1 1 -0.426 -0.018 0.102  
ATOM   8219  C  CG2 . ILE C 1 269 ? -46.219 -0.198  42.57   1    126.99 ? 258 ILE C CG2 1 -0.424 -0.002 0.106  
ATOM   8220  C  CD1 . ILE C 1 269 ? -47.175 -1.919  39.487  1    120.35 ? 258 ILE C CD1 1 -0.432 -0.018 0.099  
ATOM   8221  N  N   . ASN C 1 270 ? -50.211 -1.172  43.62   1    134.46 ? 259 ASN C N   1 -0.46  -0.011 0.109  
ATOM   8222  C  CA  . ASN C 1 270 ? -51.14  -0.482  44.514  1    137.83 ? 259 ASN C CA  1 -0.469 -0.004 0.111  
ATOM   8223  C  C   . ASN C 1 270 ? -51.12  -1.098  45.915  1    133.99 ? 259 ASN C C   1 -0.468 -0.01  0.115  
ATOM   8224  O  O   . ASN C 1 270 ? -50.794 -0.416  46.895  1    133.62 ? 259 ASN C O   1 -0.465 -0.004 0.117  
ATOM   8225  C  CB  . ASN C 1 270 ? -52.559 -0.493  43.924  1    138.74 ? 259 ASN C CB  1 -0.482 -0.005 0.11   
ATOM   8226  C  CG  . ASN C 1 270 ? -52.733 0.483   42.741  1    132.09 ? 259 ASN C CG  1 -0.483 0.004  0.107  
ATOM   8227  O  OD1 . ASN C 1 270 ? -52.22  1.606   42.747  1    129.05 ? 259 ASN C OD1 1 -0.479 0.015  0.107  
ATOM   8228  N  ND2 . ASN C 1 270 ? -53.481 0.051   41.733  1    132.28 ? 259 ASN C ND2 1 -0.49  0.0    0.104  
ATOM   8229  N  N   . ASN C 1 271 ? -51.442 -2.398  46.034  1    129.08 ? 260 ASN C N   1 -0.471 -0.022 0.115  
ATOM   8230  C  CA  . ASN C 1 271 ? -51.483 -3.017  47.36   1    142.77 ? 260 ASN C CA  1 -0.472 -0.028 0.118  
ATOM   8231  C  C   . ASN C 1 271 ? -50.116 -3.066  48.038  1    139.83 ? 260 ASN C C   1 -0.459 -0.028 0.12   
ATOM   8232  O  O   . ASN C 1 271 ? -50.051 -3.207  49.266  1    143.59 ? 260 ASN C O   1 -0.459 -0.029 0.123  
ATOM   8233  C  CB  . ASN C 1 271 ? -52.067 -4.438  47.304  1    143.54 ? 260 ASN C CB  1 -0.477 -0.041 0.118  
ATOM   8234  C  CG  . ASN C 1 271 ? -52.388 -5.005  48.711  1    147.06 ? 260 ASN C CG  1 -0.48  -0.046 0.122  
ATOM   8235  O  OD1 . ASN C 1 271 ? -52.648 -4.252  49.662  1    140.54 ? 260 ASN C OD1 1 -0.482 -0.039 0.124  
ATOM   8236  N  ND2 . ASN C 1 271 ? -52.364 -6.332  48.835  1    146.7  ? 260 ASN C ND2 1 -0.48  -0.058 0.122  
ATOM   8237  N  N   . GLU C 1 272 ? -49.027 -2.957  47.281  1    137.25 ? 261 GLU C N   1 -0.449 -0.027 0.118  
ATOM   8238  C  CA  . GLU C 1 272 ? -47.707 -2.928  47.896  1    137.67 ? 261 GLU C CA  1 -0.437 -0.027 0.12   
ATOM   8239  C  C   . GLU C 1 272 ? -47.225 -1.508  48.163  1    134.87 ? 261 GLU C C   1 -0.433 -0.014 0.12   
ATOM   8240  O  O   . GLU C 1 272 ? -46.247 -1.322  48.896  1    131.79 ? 261 GLU C O   1 -0.424 -0.012 0.122  
ATOM   8241  C  CB  . GLU C 1 272 ? -46.702 -3.686  47.014  1    135.78 ? 261 GLU C CB  1 -0.428 -0.034 0.117  
ATOM   8242  C  CG  . GLU C 1 272 ? -47.187 -5.087  46.587  1    134.26 ? 261 GLU C CG  1 -0.432 -0.047 0.116  
ATOM   8243  C  CD  . GLU C 1 272 ? -46.909 -6.207  47.603  1    137.9  ? 261 GLU C CD  1 -0.43  -0.057 0.119  
ATOM   8244  O  OE1 . GLU C 1 272 ? -45.742 -6.355  48.032  1    140.03 ? 261 GLU C OE1 1 -0.419 -0.058 0.12   
ATOM   8245  O  OE2 . GLU C 1 272 ? -47.853 -6.954  47.96   1    133.93 ? 261 GLU C OE2 1 -0.439 -0.064 0.12   
ATOM   8246  N  N   . PHE C 1 273 ? -47.887 -0.509  47.586  1    137.17 ? 262 PHE C N   1 -0.439 -0.005 0.119  
ATOM   8247  C  CA  . PHE C 1 273 ? -47.642 0.893   47.893  1    137.62 ? 262 PHE C CA  1 -0.437 0.008  0.12   
ATOM   8248  C  C   . PHE C 1 273 ? -48.817 1.516   48.617  1    135.83 ? 262 PHE C C   1 -0.447 0.014  0.121  
ATOM   8249  O  O   . PHE C 1 273 ? -48.753 2.701   48.968  1    135.45 ? 262 PHE C O   1 -0.447 0.025  0.122  
ATOM   8250  C  CB  . PHE C 1 273 ? -47.338 1.689   46.61   1    138.03 ? 262 PHE C CB  1 -0.434 0.015  0.116  
ATOM   8251  C  CG  . PHE C 1 273 ? -45.875 1.757   46.275  1    132.92 ? 262 PHE C CG  1 -0.42  0.016  0.116  
ATOM   8252  C  CD1 . PHE C 1 273 ? -45.164 0.596   46.012  1    136.53 ? 262 PHE C CD1 1 -0.414 0.005  0.115  
ATOM   8253  C  CD2 . PHE C 1 273 ? -45.207 2.974   46.245  1    127.31 ? 262 PHE C CD2 1 -0.414 0.027  0.115  
ATOM   8254  C  CE1 . PHE C 1 273 ? -43.81  0.645   45.722  1    138.08 ? 262 PHE C CE1 1 -0.401 0.006  0.114  
ATOM   8255  C  CE2 . PHE C 1 273 ? -43.855 3.034   45.956  1    126.98 ? 262 PHE C CE2 1 -0.402 0.028  0.115  
ATOM   8256  C  CZ  . PHE C 1 273 ? -43.153 1.869   45.694  1    132.66 ? 262 PHE C CZ  1 -0.395 0.017  0.114  
ATOM   8257  N  N   . ASN C 1 274 ? -49.895 0.749   48.813  1    138.43 ? 263 ASN C N   1 -0.457 0.007  0.122  
ATOM   8258  C  CA  . ASN C 1 274 ? -51.063 1.151   49.609  1    144.96 ? 263 ASN C CA  1 -0.468 0.011  0.124  
ATOM   8259  C  C   . ASN C 1 274 ? -51.561 2.541   49.222  1    143.68 ? 263 ASN C C   1 -0.473 0.023  0.123  
ATOM   8260  O  O   . ASN C 1 274 ? -52.039 3.307   50.066  1    147.5  ? 263 ASN C O   1 -0.477 0.03   0.125  
ATOM   8261  C  CB  . ASN C 1 274 ? -50.767 1.062   51.114  1    136.91 ? 263 ASN C CB  1 -0.465 0.01   0.128  
ATOM   8262  C  CG  . ASN C 1 274 ? -50.469 -0.366  51.563  1    137.65 ? 263 ASN C CG  1 -0.463 -0.003 0.129  
ATOM   8263  O  OD1 . ASN C 1 274 ? -51.35  -1.232  51.534  1    138.14 ? 263 ASN C OD1 1 -0.471 -0.011 0.129  
ATOM   8264  N  ND2 . ASN C 1 274 ? -49.22  -0.621  51.965  1    131.41 ? 263 ASN C ND2 1 -0.451 -0.006 0.13   
ATOM   8265  N  N   . SER C 1 275 ? -51.439 2.868   47.936  1    134.68 ? 264 SER C N   1 -0.471 0.026  0.12   
ATOM   8266  C  CA  . SER C 1 275 ? -51.986 4.089   47.369  1    138.97 ? 264 SER C CA  1 -0.476 0.037  0.118  
ATOM   8267  C  C   . SER C 1 275 ? -52.283 3.814   45.904  1    134.65 ? 264 SER C C   1 -0.479 0.035  0.115  
ATOM   8268  O  O   . SER C 1 275 ? -51.701 2.905   45.31   1    137.29 ? 264 SER C O   1 -0.474 0.027  0.113  
ATOM   8269  C  CB  . SER C 1 275 ? -51.022 5.273   47.524  1    138.97 ? 264 SER C CB  1 -0.468 0.048  0.119  
ATOM   8270  O  OG  . SER C 1 275 ? -50.039 5.269   46.505  1    130.33 ? 264 SER C OG  1 -0.459 0.048  0.116  
ATOM   8271  N  N   . GLU C 1 276 ? -53.216 4.571   45.33   1    129.19 ? 265 GLU C N   1 -0.488 0.042  0.113  
ATOM   8272  C  CA  . GLU C 1 276 ? -53.618 4.365   43.938  1    136.89 ? 265 GLU C CA  1 -0.491 0.04   0.11   
ATOM   8273  C  C   . GLU C 1 276 ? -52.829 5.325   43.057  1    141.9  ? 265 GLU C C   1 -0.484 0.049  0.108  
ATOM   8274  O  O   . GLU C 1 276 ? -53.003 6.546   43.147  1    148.05 ? 265 GLU C O   1 -0.486 0.06   0.108  
ATOM   8275  C  CB  . GLU C 1 276 ? -55.12  4.563   43.754  1    136.42 ? 265 GLU C CB  1 -0.505 0.042  0.109  
ATOM   8276  C  CG  . GLU C 1 276 ? -55.921 3.277   43.816  1    139.19 ? 265 GLU C CG  1 -0.512 0.03   0.109  
ATOM   8277  C  CD  . GLU C 1 276 ? -57.383 3.473   43.448  1    148.84 ? 265 GLU C CD  1 -0.526 0.032  0.108  
ATOM   8278  O  OE1 . GLU C 1 276 ? -57.677 4.275   42.531  1    143.72 ? 265 GLU C OE1 1 -0.529 0.039  0.106  
ATOM   8279  O  OE2 . GLU C 1 276 ? -58.239 2.818   44.084  1    153.41 ? 265 GLU C OE2 1 -0.534 0.026  0.11   
ATOM   8280  N  N   . GLY C 1 277 ? -51.963 4.777   42.208  1    134.48 ? 266 GLY C N   1 -0.476 0.044  0.105  
ATOM   8281  C  CA  . GLY C 1 277 ? -51.136 5.623   41.368  1    135.62 ? 266 GLY C CA  1 -0.469 0.052  0.103  
ATOM   8282  C  C   . GLY C 1 277 ? -51.973 6.446   40.408  1    138.86 ? 266 GLY C C   1 -0.476 0.059  0.101  
ATOM   8283  O  O   . GLY C 1 277 ? -53.012 6.004   39.911  1    139.53 ? 266 GLY C O   1 -0.486 0.055  0.1    
ATOM   8284  N  N   . VAL C 1 278 ? -51.516 7.665   40.154  1    140.31 ? 267 VAL C N   1 -0.472 0.07   0.1    
ATOM   8285  C  CA  . VAL C 1 278 ? -52.205 8.569   39.238  1    141.14 ? 267 VAL C CA  1 -0.478 0.079  0.098  
ATOM   8286  C  C   . VAL C 1 278 ? -51.65  8.352   37.835  1    139.15 ? 267 VAL C C   1 -0.473 0.077  0.094  
ATOM   8287  O  O   . VAL C 1 278 ? -50.436 8.194   37.653  1    138.51 ? 267 VAL C O   1 -0.462 0.075  0.094  
ATOM   8288  C  CB  . VAL C 1 278 ? -52.064 10.035  39.71   1    141.2  ? 267 VAL C CB  1 -0.477 0.092  0.099  
ATOM   8289  C  CG1 . VAL C 1 278 ? -52.308 10.129  41.226  1    142.55 ? 267 VAL C CG1 1 -0.479 0.093  0.103  
ATOM   8290  C  CG2 . VAL C 1 278 ? -50.705 10.621  39.369  1    132.34 ? 267 VAL C CG2 1 -0.465 0.097  0.098  
ATOM   8291  N  N   . ASP C 1 279 ? -52.544 8.28    36.842  1    141.82 ? 268 ASP C N   1 -0.482 0.076  0.092  
ATOM   8292  C  CA  . ASP C 1 279 ? -52.147 8.122   35.438  1    140.06 ? 268 ASP C CA  1 -0.478 0.074  0.088  
ATOM   8293  C  C   . ASP C 1 279 ? -51.782 9.496   34.895  1    138.39 ? 268 ASP C C   1 -0.475 0.087  0.087  
ATOM   8294  O  O   . ASP C 1 279 ? -52.659 10.29   34.547  1    139.41 ? 268 ASP C O   1 -0.483 0.094  0.086  
ATOM   8295  C  CB  . ASP C 1 279 ? -53.265 7.481   34.614  1    141.32 ? 268 ASP C CB  1 -0.488 0.069  0.086  
ATOM   8296  C  CG  . ASP C 1 279 ? -52.937 7.401   33.099  1    146.66 ? 268 ASP C CG  1 -0.485 0.068  0.083  
ATOM   8297  O  OD1 . ASP C 1 279 ? -52.745 8.455   32.447  1    142.93 ? 268 ASP C OD1 1 -0.483 0.077  0.081  
ATOM   8298  O  OD2 . ASP C 1 279 ? -52.882 6.272   32.55   1    145.7  ? 268 ASP C OD2 1 -0.485 0.057  0.081  
ATOM   8299  N  N   . ILE C 1 280 ? -50.483 9.79    34.827  1    137.08 ? 269 ILE C N   1 -0.463 0.09   0.087  
ATOM   8300  C  CA  . ILE C 1 280 ? -50.068 11.079  34.288  1    143.95 ? 269 ILE C CA  1 -0.459 0.102  0.086  
ATOM   8301  C  C   . ILE C 1 280 ? -50.401 11.149  32.803  1    149.9  ? 269 ILE C C   1 -0.462 0.102  0.082  
ATOM   8302  O  O   . ILE C 1 280 ? -50.841 12.19   32.295  1    154.5  ? 269 ILE C O   1 -0.466 0.112  0.081  
ATOM   8303  C  CB  . ILE C 1 280 ? -48.571 11.329  34.573  1    143.33 ? 269 ILE C CB  1 -0.445 0.104  0.086  
ATOM   8304  C  CG1 . ILE C 1 280 ? -48.025 12.489  33.725  1    144.43 ? 269 ILE C CG1 1 -0.44  0.114  0.084  
ATOM   8305  C  CG2 . ILE C 1 280 ? -47.749 10.057  34.391  1    135.18 ? 269 ILE C CG2 1 -0.438 0.092  0.086  
ATOM   8306  C  CD1 . ILE C 1 280 ? -48.626 13.845  34.058  1    141.14 ? 269 ILE C CD1 1 -0.446 0.127  0.085  
ATOM   8307  N  N   . GLY C 1 281 ? -50.251 10.033  32.101  1    147.98 ? 270 GLY C N   1 -0.461 0.092  0.08   
ATOM   8308  C  CA  . GLY C 1 281 ? -50.609 9.976   30.697  1    145.43 ? 270 GLY C CA  1 -0.464 0.091  0.077  
ATOM   8309  C  C   . GLY C 1 281 ? -50.294 8.612   30.127  1    147.67 ? 270 GLY C C   1 -0.461 0.079  0.075  
ATOM   8310  O  O   . GLY C 1 281 ? -49.793 7.721   30.824  1    146.43 ? 270 GLY C O   1 -0.456 0.071  0.077  
ATOM   8311  N  N   . LYS C 1 282 ? -50.64  8.456   28.845  1    153.2  ? 271 LYS C N   1 -0.464 0.077  0.072  
ATOM   8312  C  CA  . LYS C 1 282 ? -50.281 7.316   27.998  1    149.97 ? 271 LYS C CA  1 -0.461 0.067  0.07   
ATOM   8313  C  C   . LYS C 1 282 ? -50.102 5.993   28.749  1    150.25 ? 271 LYS C C   1 -0.459 0.055  0.072  
ATOM   8314  O  O   . LYS C 1 282 ? -49.287 5.153   28.345  1    145.38 ? 271 LYS C O   1 -0.452 0.047  0.071  
ATOM   8315  C  CB  . LYS C 1 282 ? -49.002 7.641   27.225  1    145.39 ? 271 LYS C CB  1 -0.449 0.07   0.068  
ATOM   8316  C  CG  . LYS C 1 282 ? -48.535 9.1     27.324  1    151.09 ? 271 LYS C CG  1 -0.445 0.083  0.068  
ATOM   8317  C  CD  . LYS C 1 282 ? -49.401 10.11   26.53   1    157.1  ? 271 LYS C CD  1 -0.453 0.093  0.066  
ATOM   8318  C  CE  . LYS C 1 282 ? -48.865 11.529  26.75   1    155.61 ? 271 LYS C CE  1 -0.448 0.106  0.067  
ATOM   8319  N  NZ  . LYS C 1 282 ? -49.946 12.536  26.961  1    153.42 ? 271 LYS C NZ  1 -0.458 0.115  0.067  
ATOM   8320  N  N   . ASN C 1 283 ? -50.878 5.803   29.831  1    149.38 ? 272 ASN C N   1 -0.466 0.053  0.074  
ATOM   8321  C  CA  . ASN C 1 283 ? -50.869 4.583   30.645  1    140.97 ? 272 ASN C CA  1 -0.466 0.042  0.077  
ATOM   8322  C  C   . ASN C 1 283 ? -49.495 4.366   31.27   1    139.7  ? 272 ASN C C   1 -0.454 0.04   0.078  
ATOM   8323  O  O   . ASN C 1 283 ? -48.873 3.309   31.116  1    134.96 ? 272 ASN C O   1 -0.448 0.03   0.078  
ATOM   8324  C  CB  . ASN C 1 283 ? -51.321 3.375   29.822  1    147.34 ? 272 ASN C CB  1 -0.47  0.031  0.074  
ATOM   8325  C  CG  . ASN C 1 283 ? -52.452 3.719   28.845  1    155.13 ? 272 ASN C CG  1 -0.481 0.034  0.072  
ATOM   8326  O  OD1 . ASN C 1 283 ? -53.309 4.564   29.142  1    159.62 ? 272 ASN C OD1 1 -0.489 0.042  0.073  
ATOM   8327  N  ND2 . ASN C 1 283 ? -52.444 3.082   27.667  1    140.93 ? 272 ASN C ND2 1 -0.481 0.028  0.069  
ATOM   8328  N  N   . ILE C 1 284 ? -49.006 5.411   31.938  1    140.69 ? 273 ILE C N   1 -0.449 0.05   0.08   
ATOM   8329  C  CA  . ILE C 1 284 ? -47.891 5.352   32.873  1    133.22 ? 273 ILE C CA  1 -0.439 0.049  0.082  
ATOM   8330  C  C   . ILE C 1 284 ? -48.362 5.977   34.171  1    132.13 ? 273 ILE C C   1 -0.443 0.055  0.085  
ATOM   8331  O  O   . ILE C 1 284 ? -48.673 7.173   34.206  1    131.46 ? 273 ILE C O   1 -0.446 0.066  0.085  
ATOM   8332  C  CB  . ILE C 1 284 ? -46.638 6.096   32.374  1    135.7  ? 273 ILE C CB  1 -0.427 0.056  0.081  
ATOM   8333  C  CG1 . ILE C 1 284 ? -46.246 5.686   30.943  1    128.48 ? 273 ILE C CG1 1 -0.424 0.052  0.077  
ATOM   8334  C  CG2 . ILE C 1 284 ? -45.511 5.932   33.4    1    127.09 ? 273 ILE C CG2 1 -0.417 0.054  0.083  
ATOM   8335  C  CD1 . ILE C 1 284 ? -46.732 6.692   29.887  1    133.85 ? 273 ILE C CD1 1 -0.428 0.061  0.075  
ATOM   8336  N  N   . HIS C 1 285 ? -48.414 5.183   35.231  1    134.97 ? 274 HIS C N   1 -0.444 0.047  0.088  
ATOM   8337  C  CA  . HIS C 1 285 ? -48.87  5.668   36.522  1    129.49 ? 274 HIS C CA  1 -0.448 0.052  0.091  
ATOM   8338  C  C   . HIS C 1 285 ? -47.675 5.909   37.435  1    125.56 ? 274 HIS C C   1 -0.437 0.054  0.093  
ATOM   8339  O  O   . HIS C 1 285 ? -46.637 5.254   37.316  1    122    ? 274 HIS C O   1 -0.427 0.048  0.093  
ATOM   8340  C  CB  . HIS C 1 285 ? -49.856 4.679   37.147  1    131.34 ? 274 HIS C CB  1 -0.457 0.043  0.093  
ATOM   8341  C  CG  . HIS C 1 285 ? -51.016 4.348   36.256  1    137.54 ? 274 HIS C CG  1 -0.468 0.04   0.091  
ATOM   8342  N  ND1 . HIS C 1 285 ? -50.868 3.687   35.053  1    136.79 ? 274 HIS C ND1 1 -0.466 0.034  0.088  
ATOM   8343  C  CD2 . HIS C 1 285 ? -52.341 4.601   36.383  1    141.37 ? 274 HIS C CD2 1 -0.48  0.042  0.091  
ATOM   8344  C  CE1 . HIS C 1 285 ? -52.05  3.539   34.483  1    138.38 ? 274 HIS C CE1 1 -0.477 0.032  0.086  
ATOM   8345  N  NE2 . HIS C 1 285 ? -52.962 4.086   35.269  1    145.84 ? 274 HIS C NE2 1 -0.485 0.037  0.088  
ATOM   8346  N  N   . VAL C 1 286 ? -47.813 6.891   38.326  1    129.7  ? 275 VAL C N   1 -0.438 0.063  0.096  
ATOM   8347  C  CA  . VAL C 1 286 ? -46.759 7.258   39.264  1    126.12 ? 275 VAL C CA  1 -0.429 0.067  0.098  
ATOM   8348  C  C   . VAL C 1 286 ? -47.281 7.048   40.68   1    129.59 ? 275 VAL C C   1 -0.433 0.065  0.102  
ATOM   8349  O  O   . VAL C 1 286 ? -48.477 7.227   40.939  1    133.5  ? 275 VAL C O   1 -0.444 0.066  0.102  
ATOM   8350  C  CB  . VAL C 1 286 ? -46.288 8.715   39.048  1    118.14 ? 275 VAL C CB  1 -0.424 0.08   0.097  
ATOM   8351  C  CG1 . VAL C 1 286 ? -47.402 9.696   39.335  1    119.39 ? 275 VAL C CG1 1 -0.434 0.089  0.098  
ATOM   8352  C  CG2 . VAL C 1 286 ? -45.084 9.021   39.909  1    124.13 ? 275 VAL C CG2 1 -0.413 0.083  0.1    
ATOM   8353  N  N   . TRP C 1 287 ? -46.389 6.639   41.586  1    129.82 ? 276 TRP C N   1 -0.425 0.061  0.104  
ATOM   8354  C  CA  . TRP C 1 287 ? -46.707 6.454   43.001  1    129.46 ? 276 TRP C CA  1 -0.428 0.059  0.107  
ATOM   8355  C  C   . TRP C 1 287 ? -45.767 7.296   43.854  1    128.24 ? 276 TRP C C   1 -0.419 0.067  0.109  
ATOM   8356  O  O   . TRP C 1 287 ? -44.582 7.434   43.533  1    130.53 ? 276 TRP C O   1 -0.409 0.068  0.109  
ATOM   8357  C  CB  . TRP C 1 287 ? -46.601 4.98    43.413  1    125.27 ? 276 TRP C CB  1 -0.427 0.046  0.108  
ATOM   8358  C  CG  . TRP C 1 287 ? -47.799 4.155   43.049  1    129.37 ? 276 TRP C CG  1 -0.438 0.038  0.107  
ATOM   8359  C  CD1 . TRP C 1 287 ? -48.974 4.095   43.728  1    134.25 ? 276 TRP C CD1 1 -0.449 0.038  0.109  
ATOM   8360  C  CD2 . TRP C 1 287 ? -47.938 3.267   41.929  1    131.61 ? 276 TRP C CD2 1 -0.439 0.03   0.105  
ATOM   8361  N  NE1 . TRP C 1 287 ? -49.839 3.226   43.109  1    133.62 ? 276 TRP C NE1 1 -0.457 0.03   0.108  
ATOM   8362  C  CE2 . TRP C 1 287 ? -49.23  2.707   42      1    132.72 ? 276 TRP C CE2 1 -0.451 0.025  0.105  
ATOM   8363  C  CE3 . TRP C 1 287 ? -47.101 2.894   40.873  1    129.63 ? 276 TRP C CE3 1 -0.432 0.027  0.102  
ATOM   8364  C  CZ2 . TRP C 1 287 ? -49.703 1.793   41.064  1    133.02 ? 276 TRP C CZ2 1 -0.455 0.016  0.103  
ATOM   8365  C  CZ3 . TRP C 1 287 ? -47.574 1.984   39.942  1    128.85 ? 276 TRP C CZ3 1 -0.436 0.018  0.1    
ATOM   8366  C  CH2 . TRP C 1 287 ? -48.863 1.445   40.045  1    130.4  ? 276 TRP C CH2 1 -0.448 0.013  0.1    
ATOM   8367  N  N   . HIS C 1 288 ? -46.293 7.854   44.944  1    129.76 ? 277 HIS C N   1 -0.424 0.072  0.112  
ATOM   8368  C  CA  . HIS C 1 288 ? -45.543 8.778   45.787  1    130.55 ? 277 HIS C CA  1 -0.417 0.08   0.114  
ATOM   8369  C  C   . HIS C 1 288 ? -45.48  8.279   47.227  1    132.27 ? 277 HIS C C   1 -0.417 0.076  0.118  
ATOM   8370  O  O   . HIS C 1 288 ? -46.456 7.732   47.753  1    126.76 ? 277 HIS C O   1 -0.426 0.071  0.119  
ATOM   8371  C  CB  . HIS C 1 288 ? -46.159 10.175  45.759  1    127.89 ? 277 HIS C CB  1 -0.423 0.093  0.114  
ATOM   8372  C  CG  . HIS C 1 288 ? -46.306 10.74   44.384  1    131.1  ? 277 HIS C CG  1 -0.424 0.098  0.111  
ATOM   8373  N  ND1 . HIS C 1 288 ? -45.27  11.366  43.723  1    136.19 ? 277 HIS C ND1 1 -0.415 0.104  0.109  
ATOM   8374  C  CD2 . HIS C 1 288 ? -47.368 10.777  43.544  1    131.12 ? 277 HIS C CD2 1 -0.434 0.099  0.109  
ATOM   8375  C  CE1 . HIS C 1 288 ? -45.687 11.763  42.532  1    137.67 ? 277 HIS C CE1 1 -0.419 0.108  0.106  
ATOM   8376  N  NE2 . HIS C 1 288 ? -46.955 11.418  42.399  1    139.15 ? 277 HIS C NE2 1 -0.43  0.105  0.106  
ATOM   8377  N  N   . HIS C 1 289 ? -44.328 8.496   47.862  1    126.53 ? 278 HIS C N   1 -0.406 0.078  0.12   
ATOM   8378  C  CA  . HIS C 1 289 ? -44.082 8.006   49.212  1    125.4  ? 278 HIS C CA  1 -0.404 0.073  0.123  
ATOM   8379  C  C   . HIS C 1 289 ? -42.935 8.828   49.778  1    129.47 ? 278 HIS C C   1 -0.393 0.081  0.124  
ATOM   8380  O  O   . HIS C 1 289 ? -41.781 8.629   49.383  1    126.89 ? 278 HIS C O   1 -0.383 0.079  0.123  
ATOM   8381  C  CB  . HIS C 1 289 ? -43.745 6.521   49.197  1    126.4  ? 278 HIS C CB  1 -0.401 0.06   0.123  
ATOM   8382  C  CG  . HIS C 1 289 ? -43.749 5.874   50.553  1    135.87 ? 278 HIS C CG  1 -0.401 0.054  0.126  
ATOM   8383  N  ND1 . HIS C 1 289 ? -44.864 5.252   51.076  1    132.4  ? 278 HIS C ND1 1 -0.411 0.048  0.128  
ATOM   8384  C  CD2 . HIS C 1 289 ? -42.769 5.73    51.478  1    129.28 ? 278 HIS C CD2 1 -0.392 0.053  0.129  
ATOM   8385  C  CE1 . HIS C 1 289 ? -44.569 4.755   52.264  1    133.75 ? 278 HIS C CE1 1 -0.408 0.044  0.13   
ATOM   8386  N  NE2 . HIS C 1 289 ? -43.305 5.03    52.531  1    127.49 ? 278 HIS C NE2 1 -0.397 0.046  0.131  
ATOM   8387  N  N   . ASN C 1 290 ? -43.256 9.74    50.697  1    133.61 ? 279 ASN C N   1 -0.396 0.089  0.127  
ATOM   8388  C  CA  . ASN C 1 290 ? -42.276 10.636  51.306  1    135.2  ? 279 ASN C CA  1 -0.387 0.097  0.128  
ATOM   8389  C  C   . ASN C 1 290 ? -41.508 11.415  50.242  1    124.05 ? 279 ASN C C   1 -0.38  0.105  0.125  
ATOM   8390  O  O   . ASN C 1 290 ? -42.019 12.402  49.699  1    119.87 ? 279 ASN C O   1 -0.385 0.114  0.124  
ATOM   8391  C  CB  . ASN C 1 290 ? -41.311 9.86    52.22   1    134.68 ? 279 ASN C CB  1 -0.379 0.09   0.13   
ATOM   8392  C  CG  . ASN C 1 290 ? -41.618 10.059  53.703  1    131.47 ? 279 ASN C CG  1 -0.381 0.092  0.134  
ATOM   8393  O  OD1 . ASN C 1 290 ? -42.742 10.419  54.066  1    127.06 ? 279 ASN C OD1 1 -0.392 0.095  0.135  
ATOM   8394  N  ND2 . ASN C 1 290 ? -40.615 9.838   54.564  1    132.43 ? 279 ASN C ND2 1 -0.372 0.09   0.136  
ATOM   8395  N  N   . ASN C 1 291 ? -40.281 10.995  49.943  1    120.46 ? 280 ASN C N   1 -0.369 0.101  0.125  
ATOM   8396  C  CA  . ASN C 1 291 ? -39.477 11.689  48.945  1    127.9  ? 280 ASN C CA  1 -0.362 0.107  0.122  
ATOM   8397  C  C   . ASN C 1 291 ? -39.068 10.792  47.782  1    128.26 ? 280 ASN C C   1 -0.358 0.099  0.119  
ATOM   8398  O  O   . ASN C 1 291 ? -38.28  11.226  46.935  1    130.81 ? 280 ASN C O   1 -0.351 0.103  0.117  
ATOM   8399  C  CB  . ASN C 1 291 ? -38.241 12.317  49.597  1    129.19 ? 280 ASN C CB  1 -0.35  0.113  0.124  
ATOM   8400  C  CG  . ASN C 1 291 ? -38.598 13.431  50.575  1    129.13 ? 280 ASN C CG  1 -0.354 0.123  0.126  
ATOM   8401  O  OD1 . ASN C 1 291 ? -39.674 14.037  50.485  1    124.48 ? 280 ASN C OD1 1 -0.364 0.129  0.126  
ATOM   8402  N  ND2 . ASN C 1 291 ? -37.692 13.711  51.51   1    123.55 ? 280 ASN C ND2 1 -0.345 0.126  0.129  
ATOM   8403  N  N   . LEU C 1 292 ? -39.594 9.565   47.71   1    128.18 ? 281 LEU C N   1 -0.363 0.088  0.119  
ATOM   8404  C  CA  . LEU C 1 292 ? -39.374 8.661   46.585  1    122.73 ? 281 LEU C CA  1 -0.361 0.079  0.116  
ATOM   8405  C  C   . LEU C 1 292 ? -40.592 8.696   45.665  1    125.48 ? 281 LEU C C   1 -0.372 0.08   0.114  
ATOM   8406  O  O   . LEU C 1 292 ? -41.699 8.325   46.072  1    122.07 ? 281 LEU C O   1 -0.382 0.076  0.115  
ATOM   8407  C  CB  . LEU C 1 292 ? -39.108 7.232   47.069  1    121.69 ? 281 LEU C CB  1 -0.358 0.066  0.118  
ATOM   8408  C  CG  . LEU C 1 292 ? -39.566 6.043   46.21   1    119.8  ? 281 LEU C CG  1 -0.363 0.055  0.115  
ATOM   8409  C  CD1 . LEU C 1 292 ? -38.726 5.899   44.947  1    123.5  ? 281 LEU C CD1 1 -0.355 0.054  0.112  
ATOM   8410  C  CD2 . LEU C 1 292 ? -39.541 4.75    47.017  1    123.31 ? 281 LEU C CD2 1 -0.362 0.044  0.117  
ATOM   8411  N  N   . ASN C 1 293 ? -40.383 9.155   44.432  1    128.68 ? 282 ASN C N   1 -0.37  0.084  0.111  
ATOM   8412  C  CA  . ASN C 1 293 ? -41.382 9.073   43.377  1    119.58 ? 282 ASN C CA  1 -0.379 0.083  0.108  
ATOM   8413  C  C   . ASN C 1 293 ? -41.051 7.874   42.509  1    117.32 ? 282 ASN C C   1 -0.376 0.072  0.106  
ATOM   8414  O  O   . ASN C 1 293 ? -39.883 7.63    42.201  1    118.8  ? 282 ASN C O   1 -0.365 0.07   0.105  
ATOM   8415  C  CB  . ASN C 1 293 ? -41.403 10.345  42.541  1    117    ? 282 ASN C CB  1 -0.379 0.095  0.106  
ATOM   8416  C  CG  . ASN C 1 293 ? -41.309 11.589  43.393  1    120.84 ? 282 ASN C CG  1 -0.379 0.106  0.108  
ATOM   8417  O  OD1 . ASN C 1 293 ? -40.219 12.116  43.633  1    120.56 ? 282 ASN C OD1 1 -0.369 0.111  0.109  
ATOM   8418  N  ND2 . ASN C 1 293 ? -42.45  12.059  43.873  1    121.12 ? 282 ASN C ND2 1 -0.389 0.111  0.11   
ATOM   8419  N  N   . TYR C 1 294 ? -42.071 7.105   42.148  1    116.7  ? 283 TYR C N   1 -0.386 0.065  0.105  
ATOM   8420  C  CA  . TYR C 1 294 ? -41.87  5.854   41.43   1    118.86 ? 283 TYR C CA  1 -0.384 0.054  0.103  
ATOM   8421  C  C   . TYR C 1 294 ? -42.828 5.811   40.247  1    124.21 ? 283 TYR C C   1 -0.392 0.053  0.1    
ATOM   8422  O  O   . TYR C 1 294 ? -44.037 5.608   40.428  1    120.63 ? 283 TYR C O   1 -0.404 0.051  0.101  
ATOM   8423  C  CB  . TYR C 1 294 ? -42.073 4.648   42.346  1    116.61 ? 283 TYR C CB  1 -0.386 0.043  0.106  
ATOM   8424  C  CG  . TYR C 1 294 ? -41.998 3.326   41.623  1    120.99 ? 283 TYR C CG  1 -0.385 0.03   0.104  
ATOM   8425  C  CD1 . TYR C 1 294 ? -40.773 2.732   41.354  1    121.75 ? 283 TYR C CD1 1 -0.374 0.025  0.103  
ATOM   8426  C  CD2 . TYR C 1 294 ? -43.153 2.674   41.194  1    124.7  ? 283 TYR C CD2 1 -0.395 0.025  0.103  
ATOM   8427  C  CE1 . TYR C 1 294 ? -40.692 1.518   40.678  1    117.2  ? 283 TYR C CE1 1 -0.373 0.014  0.102  
ATOM   8428  C  CE2 . TYR C 1 294 ? -43.084 1.459   40.519  1    122.21 ? 283 TYR C CE2 1 -0.395 0.013  0.101  
ATOM   8429  C  CZ  . TYR C 1 294 ? -41.848 0.885   40.27   1    117.1  ? 283 TYR C CZ  1 -0.384 0.008  0.101  
ATOM   8430  O  OH  . TYR C 1 294 ? -41.765 -0.318  39.612  1    111.08 ? 283 TYR C OH  1 -0.383 -0.003 0.099  
ATOM   8431  N  N   . TYR C 1 295 ? -42.278 6.006   39.041  1    120.3  ? 284 TYR C N   1 -0.387 0.055  0.097  
ATOM   8432  C  CA  . TYR C 1 295 ? -43.04  5.92    37.802  1    117.62 ? 284 TYR C CA  1 -0.394 0.054  0.094  
ATOM   8433  C  C   . TYR C 1 295 ? -42.91  4.527   37.204  1    117.56 ? 284 TYR C C   1 -0.393 0.041  0.093  
ATOM   8434  O  O   . TYR C 1 295 ? -41.808 3.977   37.109  1    114.65 ? 284 TYR C O   1 -0.383 0.036  0.093  
ATOM   8435  C  CB  . TYR C 1 295 ? -42.55  6.93    36.774  1    116.85 ? 284 TYR C CB  1 -0.39  0.064  0.092  
ATOM   8436  C  CG  . TYR C 1 295 ? -42.504 8.378   37.188  1    116.16 ? 284 TYR C CG  1 -0.39  0.077  0.093  
ATOM   8437  C  CD1 . TYR C 1 295 ? -41.432 8.879   37.904  1    117.55 ? 284 TYR C CD1 1 -0.38  0.081  0.095  
ATOM   8438  C  CD2 . TYR C 1 295 ? -43.496 9.265   36.792  1    116.98 ? 284 TYR C CD2 1 -0.399 0.085  0.092  
ATOM   8439  C  CE1 . TYR C 1 295 ? -41.371 10.216  38.249  1    120.58 ? 284 TYR C CE1 1 -0.379 0.094  0.096  
ATOM   8440  C  CE2 . TYR C 1 295 ? -43.442 10.602  37.135  1    112.63 ? 284 TYR C CE2 1 -0.398 0.097  0.093  
ATOM   8441  C  CZ  . TYR C 1 295 ? -42.378 11.074  37.857  1    114.93 ? 284 TYR C CZ  1 -0.388 0.101  0.095  
ATOM   8442  O  OH  . TYR C 1 295 ? -42.322 12.405  38.195  1    117.35 ? 284 TYR C OH  1 -0.388 0.114  0.095  
ATOM   8443  N  N   . ALA C 1 296 ? -44.035 3.974   36.766  1    120.03 ? 285 ALA C N   1 -0.404 0.036  0.092  
ATOM   8444  C  CA  . ALA C 1 296 ? -44.087 2.617   36.224  1    119.83 ? 285 ALA C CA  1 -0.404 0.024  0.09   
ATOM   8445  C  C   . ALA C 1 296 ? -44.436 2.709   34.742  1    116.48 ? 285 ALA C C   1 -0.407 0.025  0.087  
ATOM   8446  O  O   . ALA C 1 296 ? -45.599 2.897   34.369  1    117.65 ? 285 ALA C O   1 -0.418 0.027  0.086  
ATOM   8447  C  CB  . ALA C 1 296 ? -45.082 1.753   36.996  1    126.21 ? 285 ALA C CB  1 -0.413 0.016  0.092  
ATOM   8448  N  N   . VAL C 1 297 ? -43.407 2.58    33.911  1    114.6  ? 286 VAL C N   1 -0.398 0.024  0.085  
ATOM   8449  C  CA  . VAL C 1 297 ? -43.532 2.63    32.46   1    116.85 ? 286 VAL C CA  1 -0.399 0.024  0.081  
ATOM   8450  C  C   . VAL C 1 297 ? -43.776 1.204   31.972  1    113.32 ? 286 VAL C C   1 -0.401 0.011  0.08   
ATOM   8451  O  O   . VAL C 1 297 ? -42.87  0.364   32.007  1    111.51 ? 286 VAL C O   1 -0.393 0.003  0.08   
ATOM   8452  C  CB  . VAL C 1 297 ? -42.275 3.241   31.828  1    111.4  ? 286 VAL C CB  1 -0.387 0.03   0.079  
ATOM   8453  C  CG1 . VAL C 1 297 ? -42.181 2.856   30.385  1    117.82 ? 286 VAL C CG1 1 -0.387 0.026  0.076  
ATOM   8454  C  CG2 . VAL C 1 297 ? -42.27  4.76    31.97   1    103.1  ? 286 VAL C CG2 1 -0.387 0.044  0.08   
ATOM   8455  N  N   . ASP C 1 298 ? -45.005 0.91    31.535  1    111.19 ? 287 ASP C N   1 -0.412 0.008  0.079  
ATOM   8456  C  CA  . ASP C 1 298 ? -45.386 -0.443  31.139  1    118.85 ? 287 ASP C CA  1 -0.416 -0.004 0.078  
ATOM   8457  C  C   . ASP C 1 298 ? -45.222 -0.608  29.629  1    119.76 ? 287 ASP C C   1 -0.414 -0.006 0.074  
ATOM   8458  O  O   . ASP C 1 298 ? -46.073 -0.159  28.854  1    121.32 ? 287 ASP C O   1 -0.422 -0.001 0.072  
ATOM   8459  C  CB  . ASP C 1 298 ? -46.821 -0.758  31.554  1    122.52 ? 287 ASP C CB  1 -0.429 -0.007 0.079  
ATOM   8460  C  CG  . ASP C 1 298 ? -47.139 -2.245  31.477  1    123.31 ? 287 ASP C CG  1 -0.432 -0.021 0.079  
ATOM   8461  O  OD1 . ASP C 1 298 ? -46.202 -3.034  31.225  1    121.31 ? 287 ASP C OD1 1 -0.423 -0.028 0.078  
ATOM   8462  O  OD2 . ASP C 1 298 ? -48.314 -2.628  31.666  1    124.8  ? 287 ASP C OD2 1 -0.443 -0.024 0.079  
ATOM   8463  N  N   . LEU C 1 299 ? -44.149 -1.288  29.22   1    117.61 ? 288 LEU C N   1 -0.405 -0.012 0.073  
ATOM   8464  C  CA  . LEU C 1 299 ? -43.922 -1.542  27.801  1    118.75 ? 288 LEU C CA  1 -0.403 -0.014 0.069  
ATOM   8465  C  C   . LEU C 1 299 ? -45.096 -2.262  27.148  1    121.12 ? 288 LEU C C   1 -0.413 -0.021 0.068  
ATOM   8466  O  O   . LEU C 1 299 ? -45.122 -2.383  25.922  1    126.68 ? 288 LEU C O   1 -0.414 -0.022 0.065  
ATOM   8467  C  CB  . LEU C 1 299 ? -42.627 -2.341  27.594  1    110.44 ? 288 LEU C CB  1 -0.391 -0.021 0.069  
ATOM   8468  C  CG  . LEU C 1 299 ? -41.237 -1.737  27.786  1    103.88 ? 288 LEU C CG  1 -0.378 -0.016 0.069  
ATOM   8469  C  CD1 . LEU C 1 299 ? -40.573 -2.377  28.978  1    112.67 ? 288 LEU C CD1 1 -0.372 -0.022 0.072  
ATOM   8470  C  CD2 . LEU C 1 299 ? -40.409 -1.856  26.468  1    119.9  ? 288 LEU C CD2 1 -0.37  -0.017 0.066  
ATOM   8471  N  N   . SER C 1 300 ? -46.079 -2.724  27.924  1    122.72 ? 289 SER C N   1 -0.422 -0.025 0.07   
ATOM   8472  C  CA  . SER C 1 300 ? -47.244 -3.378  27.342  1    123.41 ? 289 SER C CA  1 -0.433 -0.031 0.068  
ATOM   8473  C  C   . SER C 1 300 ? -48.232 -2.379  26.766  1    124.77 ? 289 SER C C   1 -0.442 -0.022 0.067  
ATOM   8474  O  O   . SER C 1 300 ? -48.927 -2.687  25.789  1    123.21 ? 289 SER C O   1 -0.448 -0.025 0.064  
ATOM   8475  C  CB  . SER C 1 300 ? -47.962 -4.23   28.39   1    124.87 ? 289 SER C CB  1 -0.44  -0.039 0.071  
ATOM   8476  O  OG  . SER C 1 300 ? -47.187 -5.353  28.76   1    122.99 ? 289 SER C OG  1 -0.432 -0.049 0.072  
ATOM   8477  N  N   . LEU C 1 301 ? -48.333 -1.199  27.37   1    125.76 ? 290 LEU C N   1 -0.443 -0.011 0.068  
ATOM   8478  C  CA  . LEU C 1 301 ? -49.272 -0.18   26.933  1    125.46 ? 290 LEU C CA  1 -0.452 -0.002 0.067  
ATOM   8479  C  C   . LEU C 1 301 ? -48.553 0.964   26.235  1    128.38 ? 290 LEU C C   1 -0.445 0.009  0.066  
ATOM   8480  O  O   . LEU C 1 301 ? -48.849 1.283   25.077  1    135.11 ? 290 LEU C O   1 -0.448 0.012  0.063  
ATOM   8481  C  CB  . LEU C 1 301 ? -50.067 0.331   28.146  1    135.4  ? 290 LEU C CB  1 -0.459 0.003  0.07   
ATOM   8482  C  CG  . LEU C 1 301 ? -50.366 -0.698  29.254  1    129.57 ? 290 LEU C CG  1 -0.462 -0.006 0.073  
ATOM   8483  C  CD1 . LEU C 1 301 ? -50.915 -0.009  30.488  1    118.28 ? 290 LEU C CD1 1 -0.467 -0.0   0.076  
ATOM   8484  C  CD2 . LEU C 1 301 ? -51.324 -1.796  28.782  1    121.76 ? 290 LEU C CD2 1 -0.47  -0.016 0.072  
ATOM   8485  N  N   . THR C 1 302 ? -47.575 1.568   26.906  1    129.44 ? 291 THR C N   1 -0.436 0.014  0.067  
ATOM   8486  C  CA  . THR C 1 302 ? -46.796 2.674   26.341  1    132.36 ? 291 THR C CA  1 -0.429 0.025  0.066  
ATOM   8487  C  C   . THR C 1 302 ? -45.906 2.111   25.229  1    127.52 ? 291 THR C C   1 -0.421 0.019  0.063  
ATOM   8488  O  O   . THR C 1 302 ? -44.714 1.867   25.401  1    126.02 ? 291 THR C O   1 -0.41  0.017  0.063  
ATOM   8489  C  CB  . THR C 1 302 ? -45.989 3.35    27.455  1    123.68 ? 291 THR C CB  1 -0.421 0.031  0.069  
ATOM   8490  O  OG1 . THR C 1 302 ? -46.857 3.627   28.556  1    128.11 ? 291 THR C OG1 1 -0.429 0.033  0.071  
ATOM   8491  C  CG2 . THR C 1 302 ? -45.368 4.663   26.987  1    117.69 ? 291 THR C CG2 1 -0.416 0.043  0.067  
ATOM   8492  N  N   . SER C 1 303 ? -46.516 1.9     24.055  1    128.51 ? 292 SER C N   1 -0.426 0.017  0.06   
ATOM   8493  C  CA  . SER C 1 303 ? -45.85  1.204   22.953  1    133.04 ? 292 SER C CA  1 -0.42  0.011  0.057  
ATOM   8494  C  C   . SER C 1 303 ? -45.553 2.141   21.783  1    130.38 ? 292 SER C C   1 -0.417 0.02   0.054  
ATOM   8495  O  O   . SER C 1 303 ? -46.067 3.261   21.686  1    130.4  ? 292 SER C O   1 -0.422 0.03   0.054  
ATOM   8496  C  CB  . SER C 1 303 ? -46.685 0.001   22.488  1    132.68 ? 292 SER C CB  1 -0.428 0.0    0.056  
ATOM   8497  O  OG  . SER C 1 303 ? -48.074 0.282   22.503  1    137.31 ? 292 SER C OG  1 -0.441 0.003  0.056  
ATOM   8498  N  N   . ARG C 1 304 ? -44.7   1.647   20.888  1    127.27 ? 293 ARG C N   1 -0.41  0.015  0.052  
ATOM   8499  C  CA  . ARG C 1 304 ? -44.159 2.465   19.807  1    132.24 ? 293 ARG C CA  1 -0.405 0.023  0.049  
ATOM   8500  C  C   . ARG C 1 304 ? -45.252 2.975   18.869  1    131.2  ? 293 ARG C C   1 -0.415 0.027  0.047  
ATOM   8501  O  O   . ARG C 1 304 ? -46.112 2.211   18.421  1    128.82 ? 293 ARG C O   1 -0.423 0.02   0.046  
ATOM   8502  C  CB  . ARG C 1 304 ? -43.124 1.661   19.023  1    128.46 ? 293 ARG C CB  1 -0.395 0.015  0.047  
ATOM   8503  C  CG  . ARG C 1 304 ? -42.889 2.18    17.628  1    132.84 ? 293 ARG C CG  1 -0.393 0.02   0.044  
ATOM   8504  C  CD  . ARG C 1 304 ? -41.648 1.572   16.998  1    136.78 ? 293 ARG C CD  1 -0.382 0.014  0.042  
ATOM   8505  N  NE  . ARG C 1 304 ? -40.424 1.978   17.686  1    131.38 ? 293 ARG C NE  1 -0.37  0.018  0.044  
ATOM   8506  C  CZ  . ARG C 1 304 ? -39.575 1.142   18.267  1    121.06 ? 293 ARG C CZ  1 -0.363 0.01   0.046  
ATOM   8507  N  NH1 . ARG C 1 304 ? -39.797 -0.162  18.292  1    121.95 ? 293 ARG C NH1 1 -0.365 -0.001 0.046  
ATOM   8508  N  NH2 . ARG C 1 304 ? -38.465 1.624   18.816  1    117.48 ? 293 ARG C NH2 1 -0.352 0.015  0.047  
ATOM   8509  N  N   . LYS C 1 305 ? -45.207 4.277   18.573  1    132.5  ? 294 LYS C N   1 -0.414 0.039  0.046  
ATOM   8510  C  CA  . LYS C 1 305 ? -46.13  4.906   17.624  1    136.47 ? 294 LYS C CA  1 -0.423 0.045  0.044  
ATOM   8511  C  C   . LYS C 1 305 ? -45.415 5.166   16.299  1    132.36 ? 294 LYS C C   1 -0.416 0.047  0.041  
ATOM   8512  O  O   . LYS C 1 305 ? -45.062 6.296   15.947  1    126.59 ? 294 LYS C O   1 -0.413 0.058  0.04   
ATOM   8513  C  CB  . LYS C 1 305 ? -46.703 6.195   18.213  1    137.39 ? 294 LYS C CB  1 -0.428 0.057  0.045  
ATOM   8514  C  CG  . LYS C 1 305 ? -47.519 5.99    19.478  1    135.43 ? 294 LYS C CG  1 -0.435 0.055  0.049  
ATOM   8515  C  CD  . LYS C 1 305 ? -48.547 4.869   19.297  1    141.01 ? 294 LYS C CD  1 -0.445 0.045  0.048  
ATOM   8516  C  CE  . LYS C 1 305 ? -49.515 5.133   18.131  1    139.73 ? 294 LYS C CE  1 -0.454 0.047  0.045  
ATOM   8517  N  NZ  . LYS C 1 305 ? -50.243 3.89    17.729  1    135.16 ? 294 LYS C NZ  1 -0.46  0.036  0.044  
ATOM   8518  N  N   . SER C 1 306 ? -45.211 4.076   15.566  1    130.68 ? 295 SER C N   1 -0.414 0.037  0.039  
ATOM   8519  C  CA  . SER C 1 306 ? -44.546 4.057   14.255  1    135.5  ? 295 SER C CA  1 -0.408 0.037  0.036  
ATOM   8520  C  C   . SER C 1 306 ? -43.129 4.615   14.413  1    134.37 ? 295 SER C C   1 -0.395 0.042  0.036  
ATOM   8521  O  O   . SER C 1 306 ? -42.549 4.568   15.508  1    131.75 ? 295 SER C O   1 -0.39  0.042  0.039  
ATOM   8522  C  CB  . SER C 1 306 ? -45.398 4.784   13.213  1    138.99 ? 295 SER C CB  1 -0.416 0.044  0.033  
ATOM   8523  O  OG  . SER C 1 306 ? -44.799 6.012   12.812  1    136.73 ? 295 SER C OG  1 -0.411 0.055  0.032  
ATOM   8524  N  N   . VAL C 1 307 ? -42.592 5.144   13.309  1    129.36 ? 296 VAL C N   1 -0.39  0.047  0.033  
ATOM   8525  C  CA  . VAL C 1 307 ? -41.214 5.614   13.263  1    125.8  ? 296 VAL C CA  1 -0.378 0.051  0.033  
ATOM   8526  C  C   . VAL C 1 307 ? -40.949 6.656   14.355  1    122.53 ? 296 VAL C C   1 -0.375 0.061  0.036  
ATOM   8527  O  O   . VAL C 1 307 ? -41.827 7.446   14.732  1    118.12 ? 296 VAL C O   1 -0.383 0.068  0.037  
ATOM   8528  C  CB  . VAL C 1 307 ? -40.928 6.175   11.859  1    124.67 ? 296 VAL C CB  1 -0.375 0.057  0.03   
ATOM   8529  C  CG1 . VAL C 1 307 ? -41.945 7.235   11.508  1    120.39 ? 296 VAL C CG1 1 -0.384 0.066  0.029  
ATOM   8530  C  CG2 . VAL C 1 307 ? -39.517 6.721   11.761  1    123.14 ? 296 VAL C CG2 1 -0.362 0.062  0.029  
ATOM   8531  N  N   . GLY C 1 308 ? -39.725 6.64    14.874  1    116.45 ? 297 GLY C N   1 -0.364 0.061  0.037  
ATOM   8532  C  CA  . GLY C 1 308 ? -39.349 7.515   15.96   1    113.98 ? 297 GLY C CA  1 -0.361 0.069  0.04   
ATOM   8533  C  C   . GLY C 1 308 ? -38.866 6.712   17.147  1    115.86 ? 297 GLY C C   1 -0.356 0.062  0.043  
ATOM   8534  O  O   . GLY C 1 308 ? -39.205 5.529   17.284  1    120.57 ? 297 GLY C O   1 -0.359 0.051  0.043  
ATOM   8535  N  N   . VAL C 1 309 ? -38.062 7.339   18.009  1    116.3  ? 298 VAL C N   1 -0.349 0.067  0.045  
ATOM   8536  C  CA  . VAL C 1 309 ? -37.561 6.643   19.187  1    113.5  ? 298 VAL C CA  1 -0.344 0.061  0.048  
ATOM   8537  C  C   . VAL C 1 309 ? -38.731 6.198   20.054  1    109.4  ? 298 VAL C C   1 -0.355 0.057  0.05   
ATOM   8538  O  O   . VAL C 1 309 ? -39.728 6.916   20.202  1    109.4  ? 298 VAL C O   1 -0.364 0.063  0.05   
ATOM   8539  C  CB  . VAL C 1 309 ? -36.581 7.55    19.945  1    107.81 ? 298 VAL C CB  1 -0.335 0.069  0.05   
ATOM   8540  C  CG1 . VAL C 1 309 ? -36.511 7.153   21.391  1    104.72 ? 298 VAL C CG1 1 -0.335 0.066  0.053  
ATOM   8541  C  CG2 . VAL C 1 309 ? -35.21  7.462   19.295  1    105.28 ? 298 VAL C CG2 1 -0.323 0.068  0.048  
ATOM   8542  N  N   . HIS C 1 310 ? -38.618 4.984   20.597  1    112.48 ? 299 HIS C N   1 -0.354 0.046  0.051  
ATOM   8543  C  CA  . HIS C 1 310 ? -39.682 4.34    21.366  1    115.71 ? 299 HIS C CA  1 -0.364 0.04   0.053  
ATOM   8544  C  C   . HIS C 1 310 ? -40.182 5.242   22.501  1    113.53 ? 299 HIS C C   1 -0.368 0.048  0.056  
ATOM   8545  O  O   . HIS C 1 310 ? -39.367 5.76    23.283  1    112.95 ? 299 HIS C O   1 -0.361 0.053  0.058  
ATOM   8546  C  CB  . HIS C 1 310 ? -39.166 3.014   21.941  1    116.19 ? 299 HIS C CB  1 -0.359 0.028  0.055  
ATOM   8547  C  CG  . HIS C 1 310 ? -40.211 2.198   22.64   1    115.45 ? 299 HIS C CG  1 -0.368 0.02   0.057  
ATOM   8548  N  ND1 . HIS C 1 310 ? -40.811 2.601   23.813  1    111.5  ? 299 HIS C ND1 1 -0.374 0.024  0.059  
ATOM   8549  C  CD2 . HIS C 1 310 ? -40.757 0.996   22.336  1    120.12 ? 299 HIS C CD2 1 -0.374 0.009  0.056  
ATOM   8550  C  CE1 . HIS C 1 310 ? -41.689 1.692   24.196  1    113.72 ? 299 HIS C CE1 1 -0.382 0.016  0.06   
ATOM   8551  N  NE2 . HIS C 1 310 ? -41.671 0.703   23.322  1    118.28 ? 299 HIS C NE2 1 -0.382 0.006  0.058  
ATOM   8552  N  N   . PRO C 1 311 ? -41.505 5.398   22.663  1    113.38 ? 300 PRO C N   1 -0.38  0.049  0.057  
ATOM   8553  C  CA  . PRO C 1 311 ? -42.034 6.392   23.623  1    111.84 ? 300 PRO C CA  1 -0.385 0.059  0.059  
ATOM   8554  C  C   . PRO C 1 311 ? -41.554 6.209   25.057  1    112.64 ? 300 PRO C C   1 -0.381 0.057  0.063  
ATOM   8555  O  O   . PRO C 1 311 ? -41.437 7.201   25.788  1    113.95 ? 300 PRO C O   1 -0.38  0.066  0.064  
ATOM   8556  C  CB  . PRO C 1 311 ? -43.56  6.204   23.517  1    111.11 ? 300 PRO C CB  1 -0.399 0.057  0.059  
ATOM   8557  C  CG  . PRO C 1 311 ? -43.792 5.514   22.204  1    114.75 ? 300 PRO C CG  1 -0.401 0.051  0.055  
ATOM   8558  C  CD  . PRO C 1 311 ? -42.575 4.671   21.955  1    115.3  ? 300 PRO C CD  1 -0.39  0.043  0.055  
ATOM   8559  N  N   . ALA C 1 312 ? -41.274 4.975   25.486  1    113.31 ? 301 ALA C N   1 -0.378 0.046  0.064  
ATOM   8560  C  CA  . ALA C 1 312 ? -40.781 4.738   26.842  1    107.78 ? 301 ALA C CA  1 -0.374 0.043  0.067  
ATOM   8561  C  C   . ALA C 1 312 ? -39.417 5.38    27.065  1    109.81 ? 301 ALA C C   1 -0.361 0.049  0.068  
ATOM   8562  O  O   . ALA C 1 312 ? -39.172 5.99    28.113  1    105.1  ? 301 ALA C O   1 -0.359 0.055  0.07   
ATOM   8563  C  CB  . ALA C 1 312 ? -40.705 3.236   27.112  1    104.94 ? 301 ALA C CB  1 -0.373 0.03   0.068  
ATOM   8564  N  N   . LEU C 1 313 ? -38.509 5.243   26.097  1    112.94 ? 302 LEU C N   1 -0.353 0.048  0.065  
ATOM   8565  C  CA  . LEU C 1 313 ? -37.191 5.858   26.241  1    111.65 ? 302 LEU C CA  1 -0.341 0.054  0.066  
ATOM   8566  C  C   . LEU C 1 313 ? -37.223 7.362   26.012  1    114.04 ? 302 LEU C C   1 -0.341 0.067  0.065  
ATOM   8567  O  O   . LEU C 1 313 ? -36.373 8.076   26.562  1    112.53 ? 302 LEU C O   1 -0.333 0.074  0.066  
ATOM   8568  C  CB  . LEU C 1 313 ? -36.184 5.215   25.288  1    103.45 ? 302 LEU C CB  1 -0.332 0.048  0.063  
ATOM   8569  C  CG  . LEU C 1 313 ? -36.15  3.693   25.387  1    108.35 ? 302 LEU C CG  1 -0.331 0.034  0.063  
ATOM   8570  C  CD1 . LEU C 1 313 ? -34.954 3.109   24.648  1    109.98 ? 302 LEU C CD1 1 -0.32  0.028  0.062  
ATOM   8571  C  CD2 . LEU C 1 313 ? -36.153 3.279   26.852  1    108.02 ? 302 LEU C CD2 1 -0.331 0.03   0.067  
ATOM   8572  N  N   . LEU C 1 314 ? -38.158 7.856   25.193  1    111.31 ? 303 LEU C N   1 -0.35  0.072  0.063  
ATOM   8573  C  CA  . LEU C 1 314 ? -38.39  9.294   25.149  1    112.94 ? 303 LEU C CA  1 -0.352 0.085  0.063  
ATOM   8574  C  C   . LEU C 1 314 ? -38.667 9.789   26.564  1    113.96 ? 303 LEU C C   1 -0.354 0.09   0.066  
ATOM   8575  O  O   . LEU C 1 314 ? -37.807 10.471  27.128  1    116.27 ? 303 LEU C O   1 -0.346 0.096  0.068  
ATOM   8576  C  CB  . LEU C 1 314 ? -39.509 9.624   24.158  1    113.32 ? 303 LEU C CB  1 -0.362 0.088  0.06   
ATOM   8577  C  CG  . LEU C 1 314 ? -38.975 9.583   22.711  1    116.78 ? 303 LEU C CG  1 -0.357 0.088  0.057  
ATOM   8578  C  CD1 . LEU C 1 314 ? -40.03  9.974   21.655  1    111.78 ? 303 LEU C CD1 1 -0.367 0.091  0.054  
ATOM   8579  C  CD2 . LEU C 1 314 ? -37.678 10.419  22.529  1    108.29 ? 303 LEU C CD2 1 -0.345 0.095  0.056  
ATOM   8580  N  N   . PHE C 1 315 ? -39.799 9.383   27.168  1    116.02 ? 304 PHE C N   1 -0.365 0.086  0.068  
ATOM   8581  C  CA  . PHE C 1 315 ? -40.236 9.708   28.548  1    113.45 ? 304 PHE C CA  1 -0.369 0.089  0.071  
ATOM   8582  C  C   . PHE C 1 315 ? -39.077 9.844   29.536  1    113.07 ? 304 PHE C C   1 -0.358 0.09   0.074  
ATOM   8583  O  O   . PHE C 1 315 ? -38.949 10.879  30.205  1    108.72 ? 304 PHE C O   1 -0.357 0.1    0.075  
ATOM   8584  C  CB  . PHE C 1 315 ? -41.208 8.627   29.04   1    111.61 ? 304 PHE C CB  1 -0.378 0.079  0.073  
ATOM   8585  C  CG  . PHE C 1 315 ? -41.832 8.872   30.437  1    122.67 ? 304 PHE C CG  1 -0.383 0.081  0.076  
ATOM   8586  C  CD1 . PHE C 1 315 ? -42.875 8.052   30.867  1    124.7  ? 304 PHE C CD1 1 -0.393 0.074  0.077  
ATOM   8587  C  CD2 . PHE C 1 315 ? -41.412 9.883   31.307  1    121.92 ? 304 PHE C CD2 1 -0.38  0.091  0.078  
ATOM   8588  C  CE1 . PHE C 1 315 ? -43.473 8.233   32.138  1    126.07 ? 304 PHE C CE1 1 -0.398 0.075  0.08   
ATOM   8589  C  CE2 . PHE C 1 315 ? -42.009 10.055  32.564  1    115.54 ? 304 PHE C CE2 1 -0.385 0.092  0.081  
ATOM   8590  C  CZ  . PHE C 1 315 ? -43.035 9.235   32.976  1    116.35 ? 304 PHE C CZ  1 -0.394 0.085  0.082  
ATOM   8591  N  N   . ALA C 1 316 ? -38.268 8.791   29.661  1    112.19 ? 305 ALA C N   1 -0.351 0.081  0.074  
ATOM   8592  C  CA  . ALA C 1 316 ? -37.106 8.857   30.538  1    111.22 ? 305 ALA C CA  1 -0.34  0.081  0.076  
ATOM   8593  C  C   . ALA C 1 316 ? -36.312 10.135  30.3    1    115.15 ? 305 ALA C C   1 -0.333 0.093  0.076  
ATOM   8594  O  O   . ALA C 1 316 ? -35.947 10.839  31.252  1    118.6  ? 305 ALA C O   1 -0.329 0.099  0.078  
ATOM   8595  C  CB  . ALA C 1 316 ? -36.221 7.621   30.329  1    106.41 ? 305 ALA C CB  1 -0.332 0.07   0.076  
ATOM   8596  N  N   . LEU C 1 317 ? -36.088 10.488  29.028  1    112.53 ? 306 LEU C N   1 -0.331 0.096  0.072  
ATOM   8597  C  CA  . LEU C 1 317 ? -35.117 11.531  28.715  1    109.65 ? 306 LEU C CA  1 -0.322 0.106  0.072  
ATOM   8598  C  C   . LEU C 1 317 ? -35.631 12.927  29.073  1    117.34 ? 306 LEU C C   1 -0.327 0.118  0.073  
ATOM   8599  O  O   . LEU C 1 317 ? -34.907 13.708  29.703  1    122.14 ? 306 LEU C O   1 -0.32  0.126  0.074  
ATOM   8600  C  CB  . LEU C 1 317 ? -34.704 11.453  27.251  1    112.16 ? 306 LEU C CB  1 -0.318 0.105  0.068  
ATOM   8601  C  CG  . LEU C 1 317 ? -33.917 10.191  26.898  1    110.21 ? 306 LEU C CG  1 -0.311 0.093  0.067  
ATOM   8602  C  CD1 . LEU C 1 317 ? -33.831 9.994   25.377  1    111.5  ? 306 LEU C CD1 1 -0.31  0.092  0.063  
ATOM   8603  C  CD2 . LEU C 1 317 ? -32.535 10.261  27.5    1    102.56 ? 306 LEU C CD2 1 -0.298 0.094  0.069  
ATOM   8604  N  N   . GLU C 1 318 ? -36.869 13.284  28.685  1    116.07 ? 307 GLU C N   1 -0.338 0.122  0.072  
ATOM   8605  C  CA  . GLU C 1 318 ? -37.331 14.608  29.11   1    121.1  ? 307 GLU C CA  1 -0.342 0.134  0.073  
ATOM   8606  C  C   . GLU C 1 318 ? -37.711 14.642  30.58   1    121.97 ? 307 GLU C C   1 -0.346 0.134  0.076  
ATOM   8607  O  O   . GLU C 1 318 ? -37.864 15.739  31.131  1    123.64 ? 307 GLU C O   1 -0.347 0.144  0.078  
ATOM   8608  C  CB  . GLU C 1 318 ? -38.501 15.155  28.272  1    121.24 ? 307 GLU C CB  1 -0.353 0.139  0.071  
ATOM   8609  C  CG  . GLU C 1 318 ? -39.85  14.504  28.456  1    118.7  ? 307 GLU C CG  1 -0.365 0.133  0.071  
ATOM   8610  C  CD  . GLU C 1 318 ? -39.952 13.223  27.672  1    123.15 ? 307 GLU C CD  1 -0.366 0.121  0.069  
ATOM   8611  O  OE1 . GLU C 1 318 ? -39.036 12.401  27.839  1    124.97 ? 307 GLU C OE1 1 -0.358 0.114  0.07   
ATOM   8612  O  OE2 . GLU C 1 318 ? -40.907 13.047  26.891  1    119.03 ? 307 GLU C OE2 1 -0.375 0.12   0.067  
ATOM   8613  N  N   . GLN C 1 319 ? -37.822 13.49   31.243  1    119.07 ? 308 GLN C N   1 -0.347 0.124  0.078  
ATOM   8614  C  CA  . GLN C 1 319 ? -37.889 13.521  32.7    1    120.72 ? 308 GLN C CA  1 -0.347 0.124  0.082  
ATOM   8615  C  C   . GLN C 1 319 ? -36.543 13.891  33.292  1    118.33 ? 308 GLN C C   1 -0.335 0.127  0.083  
ATOM   8616  O  O   . GLN C 1 319 ? -36.454 14.787  34.139  1    123.72 ? 308 GLN C O   1 -0.334 0.136  0.085  
ATOM   8617  C  CB  . GLN C 1 319 ? -38.349 12.183  33.262  1    121.25 ? 308 GLN C CB  1 -0.351 0.112  0.083  
ATOM   8618  C  CG  . GLN C 1 319 ? -39.823 12.135  33.575  1    122.05 ? 308 GLN C CG  1 -0.365 0.111  0.084  
ATOM   8619  C  CD  . GLN C 1 319 ? -40.258 13.157  34.605  1    132.22 ? 308 GLN C CD  1 -0.369 0.121  0.086  
ATOM   8620  O  OE1 . GLN C 1 319 ? -41.397 13.634  34.572  1    136.3  ? 308 GLN C OE1 1 -0.379 0.125  0.086  
ATOM   8621  N  NE2 . GLN C 1 319 ? -39.364 13.486  35.54   1    135.4  ? 308 GLN C NE2 1 -0.361 0.124  0.089  
ATOM   8622  N  N   . LEU C 1 320 ? -35.488 13.185  32.876  1    113.63 ? 309 LEU C N   1 -0.325 0.121  0.082  
ATOM   8623  C  CA  . LEU C 1 320 ? -34.139 13.551  33.292  1    114.63 ? 309 LEU C CA  1 -0.313 0.124  0.083  
ATOM   8624  C  C   . LEU C 1 320 ? -33.835 14.995  32.913  1    119.53 ? 309 LEU C C   1 -0.31  0.137  0.082  
ATOM   8625  O  O   . LEU C 1 320 ? -33.245 15.738  33.702  1    111.97 ? 309 LEU C O   1 -0.305 0.144  0.084  
ATOM   8626  C  CB  . LEU C 1 320 ? -33.128 12.596  32.661  1    116.14 ? 309 LEU C CB  1 -0.304 0.115  0.082  
ATOM   8627  C  CG  . LEU C 1 320 ? -31.849 12.206  33.407  1    122.03 ? 309 LEU C CG  1 -0.292 0.112  0.083  
ATOM   8628  C  CD1 . LEU C 1 320 ? -31.063 11.249  32.507  1    125.32 ? 309 LEU C CD1 1 -0.285 0.103  0.081  
ATOM   8629  C  CD2 . LEU C 1 320 ? -31     13.402  33.829  1    114.29 ? 309 LEU C CD2 1 -0.284 0.123  0.084  
ATOM   8630  N  N   . LYS C 1 321 ? -34.261 15.417  31.713  1    124.95 ? 310 LYS C N   1 -0.314 0.141  0.079  
ATOM   8631  C  CA  . LYS C 1 321 ? -34.12  16.818  31.311  1    123.8  ? 310 LYS C CA  1 -0.313 0.154  0.078  
ATOM   8632  C  C   . LYS C 1 321 ? -34.825 17.739  32.307  1    123.92 ? 310 LYS C C   1 -0.319 0.163  0.081  
ATOM   8633  O  O   . LYS C 1 321 ? -34.282 18.781  32.697  1    122.33 ? 310 LYS C O   1 -0.314 0.172  0.082  
ATOM   8634  C  CB  . LYS C 1 321 ? -34.654 17.009  29.878  1    117.19 ? 310 LYS C CB  1 -0.318 0.156  0.075  
ATOM   8635  C  CG  . LYS C 1 321 ? -34.478 18.42   29.286  1    115.58 ? 310 LYS C CG  1 -0.316 0.169  0.073  
ATOM   8636  C  CD  . LYS C 1 321 ? -34.067 18.392  27.804  1    117.51 ? 310 LYS C CD  1 -0.312 0.169  0.069  
ATOM   8637  C  CE  . LYS C 1 321 ? -35.268 18.332  26.835  1    118.81 ? 310 LYS C CE  1 -0.323 0.168  0.067  
ATOM   8638  N  NZ  . LYS C 1 321 ? -35.695 19.66   26.259  1    99.37  ? 310 LYS C NZ  1 -0.327 0.18   0.066  
ATOM   8639  N  N   . GLU C 1 322 ? -36.012 17.344  32.768  1    124.92 ? 311 GLU C N   1 -0.33  0.159  0.082  
ATOM   8640  C  CA  . GLU C 1 322 ? -36.701 18.108  33.807  1    129.1  ? 311 GLU C CA  1 -0.336 0.166  0.084  
ATOM   8641  C  C   . GLU C 1 322 ? -35.926 18.094  35.121  1    129.39 ? 311 GLU C C   1 -0.329 0.166  0.088  
ATOM   8642  O  O   . GLU C 1 322 ? -35.69  19.145  35.732  1    131.34 ? 311 GLU C O   1 -0.327 0.175  0.089  
ATOM   8643  C  CB  . GLU C 1 322 ? -38.107 17.545  34.019  1    126.42 ? 311 GLU C CB  1 -0.349 0.161  0.085  
ATOM   8644  C  CG  . GLU C 1 322 ? -39.162 18.599  34.289  1    130.12 ? 311 GLU C CG  1 -0.359 0.17   0.086  
ATOM   8645  C  CD  . GLU C 1 322 ? -39.034 19.826  33.37   1    144.11 ? 311 GLU C CD  1 -0.358 0.182  0.083  
ATOM   8646  O  OE1 . GLU C 1 322 ? -39.129 20.971  33.88   1    138.6  ? 311 GLU C OE1 1 -0.359 0.192  0.085  
ATOM   8647  O  OE2 . GLU C 1 322 ? -38.848 19.636  32.13   1    143.31 ? 311 GLU C OE2 1 -0.356 0.18   0.08   
ATOM   8648  N  N   . SER C 1 323 ? -35.531 16.904  35.577  1    124.33 ? 312 SER C N   1 -0.326 0.155  0.089  
ATOM   8649  C  CA  . SER C 1 323 ? -34.892 16.781  36.883  1    123.04 ? 312 SER C CA  1 -0.32  0.154  0.092  
ATOM   8650  C  C   . SER C 1 323 ? -33.597 17.588  36.984  1    126.83 ? 312 SER C C   1 -0.308 0.161  0.092  
ATOM   8651  O  O   . SER C 1 323 ? -33.234 18.018  38.085  1    129.52 ? 312 SER C O   1 -0.305 0.165  0.095  
ATOM   8652  C  CB  . SER C 1 323 ? -34.619 15.314  37.194  1    117.9  ? 312 SER C CB  1 -0.317 0.14   0.093  
ATOM   8653  O  OG  . SER C 1 323 ? -34.301 15.17   38.56   1    130.81 ? 312 SER C OG  1 -0.314 0.139  0.096  
ATOM   8654  N  N   . ILE C 1 324 ? -32.884 17.801  35.866  1    123.35 ? 313 ILE C N   1 -0.301 0.163  0.09   
ATOM   8655  C  CA  . ILE C 1 324 ? -31.669 18.615  35.934  1    119.48 ? 313 ILE C CA  1 -0.29  0.171  0.09   
ATOM   8656  C  C   . ILE C 1 324 ? -31.995 20.092  35.801  1    121.1  ? 313 ILE C C   1 -0.293 0.184  0.089  
ATOM   8657  O  O   . ILE C 1 324 ? -31.221 20.944  36.254  1    121.29 ? 313 ILE C O   1 -0.286 0.192  0.091  
ATOM   8658  C  CB  . ILE C 1 324 ? -30.628 18.242  34.863  1    121.86 ? 313 ILE C CB  1 -0.281 0.167  0.087  
ATOM   8659  C  CG1 . ILE C 1 324 ? -30.612 16.759  34.535  1    120.57 ? 313 ILE C CG1 1 -0.281 0.154  0.086  
ATOM   8660  C  CG2 . ILE C 1 324 ? -29.234 18.642  35.32   1    118.84 ? 313 ILE C CG2 1 -0.268 0.171  0.088  
ATOM   8661  C  CD1 . ILE C 1 324 ? -29.935 16.491  33.199  1    122    ? 313 ILE C CD1 1 -0.274 0.151  0.083  
ATOM   8662  N  N   . ARG C 1 325 ? -33.105 20.427  35.145  1    124.94 ? 314 ARG C N   1 -0.303 0.187  0.088  
ATOM   8663  C  CA  . ARG C 1 325 ? -33.431 21.832  34.951  1    132.19 ? 314 ARG C CA  1 -0.306 0.2    0.087  
ATOM   8664  C  C   . ARG C 1 325 ? -33.951 22.465  36.233  1    132.13 ? 314 ARG C C   1 -0.311 0.206  0.09   
ATOM   8665  O  O   . ARG C 1 325 ? -33.884 23.69   36.382  1    136.03 ? 314 ARG C O   1 -0.311 0.217  0.091  
ATOM   8666  C  CB  . ARG C 1 325 ? -34.447 21.992  33.815  1    132.63 ? 314 ARG C CB  1 -0.316 0.202  0.084  
ATOM   8667  C  CG  . ARG C 1 325 ? -34.332 23.32   33.071  1    130.61 ? 314 ARG C CG  1 -0.315 0.214  0.083  
ATOM   8668  C  CD  . ARG C 1 325 ? -35.704 23.905  32.756  1    136.45 ? 314 ARG C CD  1 -0.327 0.219  0.082  
ATOM   8669  N  NE  . ARG C 1 325 ? -36.383 24.412  33.947  1    144.06 ? 314 ARG C NE  1 -0.333 0.224  0.085  
ATOM   8670  C  CZ  . ARG C 1 325 ? -37.307 23.748  34.631  1    137.02 ? 314 ARG C CZ  1 -0.342 0.218  0.086  
ATOM   8671  N  NH1 . ARG C 1 325 ? -37.678 22.526  34.286  1    134.42 ? 314 ARG C NH1 1 -0.345 0.206  0.086  
ATOM   8672  N  NH2 . ARG C 1 325 ? -37.876 24.33   35.681  1    136.79 ? 314 ARG C NH2 1 -0.347 0.223  0.089  
ATOM   8673  N  N   . GLU C 1 326 ? -34.451 21.651  37.164  1    134.81 ? 315 GLU C N   1 -0.316 0.198  0.093  
ATOM   8674  C  CA  . GLU C 1 326 ? -34.791 22.104  38.508  1    130.66 ? 315 GLU C CA  1 -0.319 0.203  0.096  
ATOM   8675  C  C   . GLU C 1 326 ? -33.626 21.955  39.47   1    126.9  ? 315 GLU C C   1 -0.308 0.201  0.099  
ATOM   8676  O  O   . GLU C 1 326 ? -33.482 22.765  40.389  1    128.64 ? 315 GLU C O   1 -0.307 0.209  0.101  
ATOM   8677  C  CB  . GLU C 1 326 ? -35.998 21.32   39.019  1    127.03 ? 315 GLU C CB  1 -0.33  0.195  0.097  
ATOM   8678  C  CG  . GLU C 1 326 ? -36.948 21.003  37.873  1    133.85 ? 315 GLU C CG  1 -0.339 0.192  0.095  
ATOM   8679  C  CD  . GLU C 1 326 ? -38.179 20.225  38.287  1    144.12 ? 315 GLU C CD  1 -0.35  0.185  0.096  
ATOM   8680  O  OE1 . GLU C 1 326 ? -39.138 20.172  37.47   1    137.82 ? 315 GLU C OE1 1 -0.359 0.185  0.094  
ATOM   8681  O  OE2 . GLU C 1 326 ? -38.188 19.677  39.419  1    146.1  ? 315 GLU C OE2 1 -0.35  0.18   0.098  
ATOM   8682  N  N   . ALA C 1 327 ? -32.779 20.949  39.258  1    127.09 ? 316 ALA C N   1 -0.3   0.192  0.098  
ATOM   8683  C  CA  . ALA C 1 327 ? -31.646 20.714  40.142  1    127    ? 316 ALA C CA  1 -0.29  0.19   0.1    
ATOM   8684  C  C   . ALA C 1 327 ? -30.498 21.686  39.903  1    125.75 ? 316 ALA C C   1 -0.279 0.199  0.1    
ATOM   8685  O  O   . ALA C 1 327 ? -29.706 21.929  40.818  1    127.02 ? 316 ALA C O   1 -0.272 0.201  0.102  
ATOM   8686  C  CB  . ALA C 1 327 ? -31.15  19.279  39.98   1    126.7  ? 316 ALA C CB  1 -0.285 0.177  0.1    
ATOM   8687  N  N   . LYS C 1 328 ? -30.354 22.225  38.693  1    129.09 ? 317 LYS C N   1 -0.278 0.204  0.097  
ATOM   8688  C  CA  . LYS C 1 328 ? -29.348 23.265  38.506  1    131.45 ? 317 LYS C CA  1 -0.269 0.213  0.096  
ATOM   8689  C  C   . LYS C 1 328 ? -29.874 24.613  38.984  1    126.48 ? 317 LYS C C   1 -0.274 0.226  0.097  
ATOM   8690  O  O   . LYS C 1 328 ? -29.102 25.435  39.503  1    120.31 ? 317 LYS C O   1 -0.267 0.233  0.099  
ATOM   8691  C  CB  . LYS C 1 328 ? -28.881 23.322  37.033  1    129.7  ? 317 LYS C CB  1 -0.265 0.214  0.092  
ATOM   8692  C  CG  . LYS C 1 328 ? -29.754 24.121  36.05   1    122.79 ? 317 LYS C CG  1 -0.273 0.221  0.09   
ATOM   8693  C  CD  . LYS C 1 328 ? -29.012 24.344  34.719  1    135.3  ? 317 LYS C CD  1 -0.266 0.223  0.087  
ATOM   8694  C  CE  . LYS C 1 328 ? -29.826 25.165  33.688  1    135.06 ? 317 LYS C CE  1 -0.273 0.231  0.084  
ATOM   8695  N  NZ  . LYS C 1 328 ? -30.941 24.407  33.023  1    130.88 ? 317 LYS C NZ  1 -0.284 0.224  0.082  
ATOM   8696  N  N   . ALA C 1 329 ? -31.188 24.825  38.86   1    122    ? 318 ALA C N   1 -0.286 0.227  0.097  
ATOM   8697  C  CA  . ALA C 1 329 ? -31.803 26.062  39.317  1    123.41 ? 318 ALA C CA  1 -0.291 0.239  0.098  
ATOM   8698  C  C   . ALA C 1 329 ? -31.527 26.299  40.804  1    128.28 ? 318 ALA C C   1 -0.289 0.241  0.102  
ATOM   8699  O  O   . ALA C 1 329 ? -30.876 27.285  41.175  1    127.84 ? 318 ALA C O   1 -0.283 0.25   0.103  
ATOM   8700  C  CB  . ALA C 1 329 ? -33.301 26.026  39.012  1    121.87 ? 318 ALA C CB  1 -0.305 0.239  0.097  
ATOM   8701  N  N   . LYS C 1 330 ? -31.982 25.386  41.675  1    123.67 ? 319 LYS C N   1 -0.293 0.233  0.104  
ATOM   8702  C  CA  . LYS C 1 330 ? -31.748 25.511  43.112  1    123.69 ? 319 LYS C CA  1 -0.291 0.234  0.108  
ATOM   8703  C  C   . LYS C 1 330 ? -30.404 24.926  43.57   1    124.18 ? 319 LYS C C   1 -0.279 0.228  0.109  
ATOM   8704  O  O   . LYS C 1 330 ? -30.257 24.593  44.75   1    121.87 ? 319 LYS C O   1 -0.277 0.225  0.112  
ATOM   8705  C  CB  . LYS C 1 330 ? -32.896 24.882  43.906  1    121.12 ? 319 LYS C CB  1 -0.301 0.228  0.11   
ATOM   8706  C  CG  . LYS C 1 330 ? -33.628 23.75   43.227  1    123.72 ? 319 LYS C CG  1 -0.308 0.218  0.108  
ATOM   8707  C  CD  . LYS C 1 330 ? -34.866 23.344  44.035  1    126.55 ? 319 LYS C CD  1 -0.32  0.214  0.11   
ATOM   8708  C  CE  . LYS C 1 330 ? -34.743 21.931  44.632  1    129.96 ? 319 LYS C CE  1 -0.318 0.201  0.111  
ATOM   8709  N  NZ  . LYS C 1 330 ? -35.861 21.558  45.574  1    114.73 ? 319 LYS C NZ  1 -0.329 0.198  0.114  
ATOM   8710  N  N   . GLY C 1 331 ? -29.434 24.798  42.669  1    124.95 ? 320 GLY C N   1 -0.27  0.227  0.107  
ATOM   8711  C  CA  . GLY C 1 331 ? -28.035 24.609  43.046  1    125.97 ? 320 GLY C CA  1 -0.257 0.226  0.107  
ATOM   8712  C  C   . GLY C 1 331 ? -27.674 23.39   43.873  1    126.43 ? 320 GLY C C   1 -0.254 0.214  0.11   
ATOM   8713  O  O   . GLY C 1 331 ? -26.821 23.49   44.767  1    124.04 ? 320 GLY C O   1 -0.246 0.215  0.112  
ATOM   8714  N  N   . GLN C 1 332 ? -28.285 22.237  43.595  1    125.93 ? 321 GLN C N   1 -0.259 0.204  0.109  
ATOM   8715  C  CA  . GLN C 1 332 ? -27.828 20.954  44.131  1    129.4  ? 321 GLN C CA  1 -0.255 0.192  0.11   
ATOM   8716  C  C   . GLN C 1 332 ? -27.531 19.996  42.971  1    124.37 ? 321 GLN C C   1 -0.252 0.183  0.107  
ATOM   8717  O  O   . GLN C 1 332 ? -27.517 20.387  41.802  1    126.39 ? 321 GLN C O   1 -0.252 0.187  0.104  
ATOM   8718  C  CB  . GLN C 1 332 ? -28.829 20.34   45.119  1    127.51 ? 321 GLN C CB  1 -0.264 0.186  0.113  
ATOM   8719  C  CG  . GLN C 1 332 ? -30.181 20.019  44.538  1    125.88 ? 321 GLN C CG  1 -0.277 0.183  0.111  
ATOM   8720  C  CD  . GLN C 1 332 ? -31.007 21.266  44.365  1    128.87 ? 321 GLN C CD  1 -0.284 0.195  0.111  
ATOM   8721  O  OE1 . GLN C 1 332 ? -30.891 21.965  43.362  1    129.99 ? 321 GLN C OE1 1 -0.283 0.201  0.108  
ATOM   8722  N  NE2 . GLN C 1 332 ? -31.821 21.574  45.363  1    128.08 ? 321 GLN C NE2 1 -0.292 0.198  0.113  
ATOM   8723  N  N   . LYS C 1 333 ? -27.268 18.735  43.311  1    122.01 ? 322 LYS C N   1 -0.25  0.172  0.108  
ATOM   8724  C  CA  . LYS C 1 333 ? -26.612 17.812  42.403  1    116.64 ? 322 LYS C CA  1 -0.244 0.163  0.106  
ATOM   8725  C  C   . LYS C 1 333 ? -27.471 16.579  42.19   1    122.57 ? 322 LYS C C   1 -0.252 0.152  0.105  
ATOM   8726  O  O   . LYS C 1 333 ? -28.252 16.187  43.065  1    119.83 ? 322 LYS C O   1 -0.259 0.148  0.108  
ATOM   8727  C  CB  . LYS C 1 333 ? -25.235 17.375  42.929  1    119.6  ? 322 LYS C CB  1 -0.231 0.159  0.107  
ATOM   8728  C  CG  . LYS C 1 333 ? -24.538 18.385  43.825  1    129.07 ? 322 LYS C CG  1 -0.225 0.168  0.109  
ATOM   8729  C  CD  . LYS C 1 333 ? -24.339 19.736  43.139  1    118.23 ? 322 LYS C CD  1 -0.223 0.181  0.108  
ATOM   8730  C  CE  . LYS C 1 333 ? -23.382 19.638  42.015  1    109.44 ? 322 LYS C CE  1 -0.214 0.18   0.105  
ATOM   8731  N  NZ  . LYS C 1 333 ? -22.026 19.31   42.489  1    106.62 ? 322 LYS C NZ  1 -0.202 0.177  0.106  
ATOM   8732  N  N   . ILE C 1 334 ? -27.306 15.965  41.012  1    123.6  ? 323 ILE C N   1 -0.25  0.146  0.102  
ATOM   8733  C  CA  . ILE C 1 334 ? -27.98  14.722  40.656  1    115.72 ? 323 ILE C CA  1 -0.256 0.135  0.102  
ATOM   8734  C  C   . ILE C 1 334 ? -26.952 13.603  40.619  1    112.27 ? 323 ILE C C   1 -0.247 0.125  0.101  
ATOM   8735  O  O   . ILE C 1 334 ? -25.829 13.784  40.137  1    108.79 ? 323 ILE C O   1 -0.237 0.126  0.1    
ATOM   8736  C  CB  . ILE C 1 334 ? -28.736 14.834  39.317  1    112.27 ? 323 ILE C CB  1 -0.263 0.136  0.098  
ATOM   8737  C  CG1 . ILE C 1 334 ? -29.746 15.983  39.385  1    110.92 ? 323 ILE C CG1 1 -0.273 0.146  0.098  
ATOM   8738  C  CG2 . ILE C 1 334 ? -29.439 13.522  38.988  1    111.37 ? 323 ILE C CG2 1 -0.27  0.124  0.097  
ATOM   8739  C  CD1 . ILE C 1 334 ? -30.948 15.826  38.483  1    110.12 ? 323 ILE C CD1 1 -0.284 0.145  0.096  
ATOM   8740  N  N   . ALA C 1 335 ? -27.313 12.473  41.209  1    119.48 ? 324 ALA C N   1 -0.25  0.114  0.103  
ATOM   8741  C  CA  . ALA C 1 335 ? -26.624 11.206  41.016  1    120.41 ? 324 ALA C CA  1 -0.244 0.103  0.102  
ATOM   8742  C  C   . ALA C 1 335 ? -27.576 10.314  40.231  1    120.42 ? 324 ALA C C   1 -0.253 0.095  0.1    
ATOM   8743  O  O   . ALA C 1 335 ? -28.766 10.225  40.565  1    115.07 ? 324 ALA C O   1 -0.264 0.094  0.101  
ATOM   8744  C  CB  . ALA C 1 335 ? -26.226 10.566  42.35   1    114.58 ? 324 ALA C CB  1 -0.24  0.097  0.106  
ATOM   8745  N  N   . LEU C 1 336 ? -27.059 9.68    39.18   1    116.08 ? 325 LEU C N   1 -0.248 0.089  0.098  
ATOM   8746  C  CA  . LEU C 1 336 ? -27.874 9.102   38.119  1    115.94 ? 325 LEU C CA  1 -0.255 0.083  0.095  
ATOM   8747  C  C   . LEU C 1 336 ? -27.522 7.626   38.004  1    114.87 ? 325 LEU C C   1 -0.252 0.07   0.095  
ATOM   8748  O  O   . LEU C 1 336 ? -26.341 7.27    37.895  1    114.42 ? 325 LEU C O   1 -0.241 0.067  0.095  
ATOM   8749  C  CB  . LEU C 1 336 ? -27.646 9.881   36.807  1    118.18 ? 325 LEU C CB  1 -0.253 0.091  0.092  
ATOM   8750  C  CG  . LEU C 1 336 ? -28.322 9.671   35.442  1    111.7  ? 325 LEU C CG  1 -0.26  0.089  0.088  
ATOM   8751  C  CD1 . LEU C 1 336 ? -27.528 8.673   34.649  1    108.94 ? 325 LEU C CD1 1 -0.252 0.079  0.087  
ATOM   8752  C  CD2 . LEU C 1 336 ? -29.797 9.269   35.553  1    109.84 ? 325 LEU C CD2 1 -0.273 0.085  0.089  
ATOM   8753  N  N   . TYR C 1 337 ? -28.537 6.764   38.094  1    109.28 ? 326 TYR C N   1 -0.262 0.062  0.095  
ATOM   8754  C  CA  . TYR C 1 337 ? -28.309 5.334   38.269  1    110.57 ? 326 TYR C CA  1 -0.259 0.049  0.096  
ATOM   8755  C  C   . TYR C 1 337 ? -29.056 4.554   37.197  1    107.54 ? 326 TYR C C   1 -0.266 0.042  0.093  
ATOM   8756  O  O   . TYR C 1 337 ? -30.285 4.655   37.095  1    107.87 ? 326 TYR C O   1 -0.278 0.043  0.093  
ATOM   8757  C  CB  . TYR C 1 337 ? -28.724 4.892   39.682  1    113.32 ? 326 TYR C CB  1 -0.263 0.045  0.099  
ATOM   8758  C  CG  . TYR C 1 337 ? -27.741 5.351   40.736  1    107.53 ? 326 TYR C CG  1 -0.254 0.049  0.102  
ATOM   8759  C  CD1 . TYR C 1 337 ? -27.903 6.571   41.383  1    111.53 ? 326 TYR C CD1 1 -0.256 0.06   0.103  
ATOM   8760  C  CD2 . TYR C 1 337 ? -26.628 4.583   41.05   1    104.84 ? 326 TYR C CD2 1 -0.244 0.042  0.102  
ATOM   8761  C  CE1 . TYR C 1 337 ? -26.994 7.006   42.338  1    114.11 ? 326 TYR C CE1 1 -0.247 0.064  0.106  
ATOM   8762  C  CE2 . TYR C 1 337 ? -25.713 5.004   41.998  1    110.1  ? 326 TYR C CE2 1 -0.236 0.046  0.105  
ATOM   8763  C  CZ  . TYR C 1 337 ? -25.9   6.215   42.64   1    112.31 ? 326 TYR C CZ  1 -0.237 0.057  0.106  
ATOM   8764  O  OH  . TYR C 1 337 ? -24.981 6.632   43.572  1    105.21 ? 326 TYR C OH  1 -0.229 0.061  0.109  
ATOM   8765  N  N   . LEU C 1 338 ? -28.308 3.776   36.401  1    107.7  ? 327 LEU C N   1 -0.259 0.035  0.091  
ATOM   8766  C  CA  . LEU C 1 338 ? -28.861 2.939   35.335  1    107.83 ? 327 LEU C CA  1 -0.264 0.027  0.088  
ATOM   8767  C  C   . LEU C 1 338 ? -28.712 1.456   35.656  1    110.03 ? 327 LEU C C   1 -0.263 0.013  0.089  
ATOM   8768  O  O   . LEU C 1 338 ? -27.668 0.849   35.356  1    105.45 ? 327 LEU C O   1 -0.254 0.008  0.088  
ATOM   8769  C  CB  . LEU C 1 338 ? -28.201 3.249   33.993  1    103.96 ? 327 LEU C CB  1 -0.258 0.03   0.085  
ATOM   8770  C  CG  . LEU C 1 338 ? -28.291 4.647   33.381  1    105.62 ? 327 LEU C CG  1 -0.259 0.043  0.083  
ATOM   8771  C  CD1 . LEU C 1 338 ? -29.648 5.304   33.662  1    103.38 ? 327 LEU C CD1 1 -0.272 0.049  0.084  
ATOM   8772  C  CD2 . LEU C 1 338 ? -27.113 5.472   33.875  1    106.9  ? 327 LEU C CD2 1 -0.248 0.05   0.085  
ATOM   8773  N  N   . PRO C 1 339 ? -29.734 0.821   36.268  1    108.62 ? 328 PRO C N   1 -0.272 0.008  0.091  
ATOM   8774  C  CA  . PRO C 1 339 ? -29.827 -0.644  36.233  1    106.12 ? 328 PRO C CA  1 -0.273 -0.006 0.09   
ATOM   8775  C  C   . PRO C 1 339 ? -30.267 -1.096  34.848  1    110.95 ? 328 PRO C C   1 -0.277 -0.01  0.087  
ATOM   8776  O  O   . PRO C 1 339 ? -31.441 -1.429  34.618  1    107.76 ? 328 PRO C O   1 -0.288 -0.013 0.086  
ATOM   8777  C  CB  . PRO C 1 339 ? -30.885 -0.965  37.299  1    101.58 ? 328 PRO C CB  1 -0.283 -0.009 0.093  
ATOM   8778  C  CG  . PRO C 1 339 ? -31.38  0.362   37.808  1    100.93 ? 328 PRO C CG  1 -0.288 0.003  0.094  
ATOM   8779  C  CD  . PRO C 1 339 ? -30.899 1.439   36.915  1    103.28 ? 328 PRO C CD  1 -0.283 0.013  0.092  
ATOM   8780  N  N   . THR C 1 340 ? -29.326 -1.076  33.905  1    108.62 ? 329 THR C N   1 -0.269 -0.01  0.085  
ATOM   8781  C  CA  . THR C 1 340 ? -29.622 -1.276  32.493  1    105.47 ? 329 THR C CA  1 -0.271 -0.012 0.081  
ATOM   8782  C  C   . THR C 1 340 ? -29.636 -2.761  32.154  1    104.19 ? 329 THR C C   1 -0.272 -0.025 0.08   
ATOM   8783  O  O   . THR C 1 340 ? -28.698 -3.49   32.497  1    99.67  ? 329 THR C O   1 -0.263 -0.032 0.081  
ATOM   8784  C  CB  . THR C 1 340 ? -28.592 -0.545  31.637  1    104.65 ? 329 THR C CB  1 -0.262 -0.005 0.079  
ATOM   8785  O  OG1 . THR C 1 340 ? -28.987 0.822   31.488  1    105.88 ? 329 THR C OG1 1 -0.266 0.008  0.079  
ATOM   8786  C  CG2 . THR C 1 340 ? -28.456 -1.199  30.274  1    102.96 ? 329 THR C CG2 1 -0.261 -0.011 0.076  
ATOM   8787  N  N   . GLY C 1 341 ? -30.695 -3.201  31.483  1    105.38 ? 330 GLY C N   1 -0.281 -0.029 0.079  
ATOM   8788  C  CA  . GLY C 1 341 ? -30.773 -4.555  30.971  1    108.49 ? 330 GLY C CA  1 -0.282 -0.042 0.077  
ATOM   8789  C  C   . GLY C 1 341 ? -30.965 -4.527  29.467  1    103.74 ? 330 GLY C C   1 -0.284 -0.041 0.074  
ATOM   8790  O  O   . GLY C 1 341 ? -31.602 -3.622  28.927  1    112.09 ? 330 GLY C O   1 -0.29  -0.033 0.072  
ATOM   8791  N  N   . TRP C 1 342 ? -30.398 -5.513  28.784  1    99.53  ? 331 TRP C N   1 -0.279 -0.051 0.072  
ATOM   8792  C  CA  . TRP C 1 342 ? -30.569 -5.575  27.337  1    106.66 ? 331 TRP C CA  1 -0.28  -0.051 0.068  
ATOM   8793  C  C   . TRP C 1 342 ? -31.602 -6.602  26.906  1    105.45 ? 331 TRP C C   1 -0.29  -0.061 0.067  
ATOM   8794  O  O   . TRP C 1 342 ? -31.825 -6.771  25.705  1    103.92 ? 331 TRP C O   1 -0.292 -0.062 0.064  
ATOM   8795  C  CB  . TRP C 1 342 ? -29.234 -5.846  26.649  1    97.42  ? 331 TRP C CB  1 -0.268 -0.054 0.067  
ATOM   8796  C  CG  . TRP C 1 342 ? -28.403 -4.613  26.576  1    102.64 ? 331 TRP C CG  1 -0.26  -0.042 0.066  
ATOM   8797  C  CD1 . TRP C 1 342 ? -28.842 -3.343  26.301  1    102.9  ? 331 TRP C CD1 1 -0.264 -0.031 0.066  
ATOM   8798  C  CD2 . TRP C 1 342 ? -26.993 -4.51   26.823  1    96.97  ? 331 TRP C CD2 1 -0.247 -0.041 0.067  
ATOM   8799  N  NE1 . TRP C 1 342 ? -27.782 -2.461  26.344  1    102.32 ? 331 TRP C NE1 1 -0.255 -0.023 0.066  
ATOM   8800  C  CE2 . TRP C 1 342 ? -26.638 -3.152  26.658  1    95.49  ? 331 TRP C CE2 1 -0.244 -0.029 0.067  
ATOM   8801  C  CE3 . TRP C 1 342 ? -25.996 -5.435  27.154  1    87.42  ? 331 TRP C CE3 1 -0.238 -0.05  0.068  
ATOM   8802  C  CZ2 . TRP C 1 342 ? -25.331 -2.7    26.808  1    91.49  ? 331 TRP C CZ2 1 -0.232 -0.025 0.067  
ATOM   8803  C  CZ3 . TRP C 1 342 ? -24.7   -4.985  27.307  1    84.97  ? 331 TRP C CZ3 1 -0.226 -0.046 0.068  
ATOM   8804  C  CH2 . TRP C 1 342 ? -24.378 -3.63   27.128  1    89.3   ? 331 TRP C CH2 1 -0.223 -0.033 0.068  
ATOM   8805  N  N   . ASP C 1 343 ? -32.243 -7.279  27.854  1    107.16 ? 332 ASP C N   1 -0.295 -0.067 0.07   
ATOM   8806  C  CA  . ASP C 1 343 ? -33.353 -8.163  27.541  1    101.91 ? 332 ASP C CA  1 -0.306 -0.075 0.069  
ATOM   8807  C  C   . ASP C 1 343 ? -34.613 -7.404  27.188  1    99.91  ? 332 ASP C C   1 -0.317 -0.068 0.068  
ATOM   8808  O  O   . ASP C 1 343 ? -35.65  -8.036  26.984  1    106.2  ? 332 ASP C O   1 -0.327 -0.074 0.067  
ATOM   8809  C  CB  . ASP C 1 343 ? -33.624 -9.116  28.713  1    112.32 ? 332 ASP C CB  1 -0.308 -0.084 0.072  
ATOM   8810  C  CG  . ASP C 1 343 ? -33.648 -8.407  30.072  1    109.86 ? 332 ASP C CG  1 -0.308 -0.077 0.075  
ATOM   8811  O  OD1 . ASP C 1 343 ? -33.011 -7.336  30.215  1    109.38 ? 332 ASP C OD1 1 -0.303 -0.067 0.075  
ATOM   8812  O  OD2 . ASP C 1 343 ? -34.303 -8.934  30.999  1    109.22 ? 332 ASP C OD2 1 -0.314 -0.082 0.077  
ATOM   8813  N  N   . SER C 1 344 ? -34.558 -6.078  27.131  1    98.1   ? 333 SER C N   1 -0.317 -0.056 0.068  
ATOM   8814  C  CA  . SER C 1 344 ? -35.643 -5.267  26.606  1    102.11 ? 333 SER C CA  1 -0.327 -0.048 0.066  
ATOM   8815  C  C   . SER C 1 344 ? -35.511 -5.042  25.111  1    108.96 ? 333 SER C C   1 -0.325 -0.046 0.063  
ATOM   8816  O  O   . SER C 1 344 ? -36.191 -4.167  24.566  1    112.23 ? 333 SER C O   1 -0.332 -0.038 0.061  
ATOM   8817  C  CB  . SER C 1 344 ? -35.698 -3.92   27.331  1    104.23 ? 333 SER C CB  1 -0.327 -0.036 0.068  
ATOM   8818  O  OG  . SER C 1 344 ? -34.421 -3.297  27.373  1    102.25 ? 333 SER C OG  1 -0.315 -0.03  0.068  
ATOM   8819  N  N   . HIS C 1 345 ? -34.648 -5.807  24.446  1    106.25 ? 334 HIS C N   1 -0.318 -0.053 0.061  
ATOM   8820  C  CA  . HIS C 1 345 ? -34.383 -5.691  23.022  1    106.4  ? 334 HIS C CA  1 -0.315 -0.052 0.057  
ATOM   8821  C  C   . HIS C 1 345 ? -35.267 -6.656  22.243  1    110.99 ? 334 HIS C C   1 -0.323 -0.061 0.056  
ATOM   8822  O  O   . HIS C 1 345 ? -35.612 -7.739  22.731  1    111.86 ? 334 HIS C O   1 -0.326 -0.071 0.057  
ATOM   8823  C  CB  . HIS C 1 345 ? -32.911 -5.998  22.743  1    109.75 ? 334 HIS C CB  1 -0.302 -0.055 0.057  
ATOM   8824  C  CG  . HIS C 1 345 ? -32.365 -5.345  21.509  1    111.14 ? 334 HIS C CG  1 -0.297 -0.049 0.054  
ATOM   8825  N  ND1 . HIS C 1 345 ? -33.154 -4.981  20.439  1    113.39 ? 334 HIS C ND1 1 -0.304 -0.046 0.051  
ATOM   8826  C  CD2 . HIS C 1 345 ? -31.102 -4.987  21.183  1    106.64 ? 334 HIS C CD2 1 -0.285 -0.046 0.053  
ATOM   8827  C  CE1 . HIS C 1 345 ? -32.399 -4.429  19.505  1    110.63 ? 334 HIS C CE1 1 -0.297 -0.041 0.049  
ATOM   8828  N  NE2 . HIS C 1 345 ? -31.15  -4.417  19.935  1    107.58 ? 334 HIS C NE2 1 -0.285 -0.04  0.05   
ATOM   8829  N  N   . GLU C 1 346 ? -35.627 -6.248  21.018  1    111.93 ? 335 GLU C N   1 -0.326 -0.057 0.052  
ATOM   8830  C  CA  . GLU C 1 346 ? -36.46  -7.089  20.159  1    110.19 ? 335 GLU C CA  1 -0.334 -0.065 0.05   
ATOM   8831  C  C   . GLU C 1 346 ? -35.721 -8.35   19.733  1    111.61 ? 335 GLU C C   1 -0.327 -0.077 0.049  
ATOM   8832  O  O   . GLU C 1 346 ? -36.352 -9.378  19.472  1    112.59 ? 335 GLU C O   1 -0.333 -0.086 0.049  
ATOM   8833  C  CB  . GLU C 1 346 ? -36.926 -6.29   18.933  1    108.84 ? 335 GLU C CB  1 -0.338 -0.058 0.047  
ATOM   8834  C  CG  . GLU C 1 346 ? -35.791 -5.566  18.212  1    113.82 ? 335 GLU C CG  1 -0.328 -0.051 0.045  
ATOM   8835  C  CD  . GLU C 1 346 ? -36.199 -4.824  16.931  1    115.48 ? 335 GLU C CD  1 -0.332 -0.044 0.042  
ATOM   8836  O  OE1 . GLU C 1 346 ? -37.357 -4.338  16.822  1    115.66 ? 335 GLU C OE1 1 -0.342 -0.04  0.042  
ATOM   8837  O  OE2 . GLU C 1 346 ? -35.323 -4.722  16.035  1    107.35 ? 335 GLU C OE2 1 -0.324 -0.043 0.04   
ATOM   8838  N  N   . ASP C 1 347 ? -34.388 -8.302  19.673  1    109.29 ? 336 ASP C N   1 -0.315 -0.076 0.049  
ATOM   8839  C  CA  . ASP C 1 347 ? -33.612 -9.491  19.348  1    107.71 ? 336 ASP C CA  1 -0.308 -0.087 0.048  
ATOM   8840  C  C   . ASP C 1 347 ? -33.374 -10.399 20.553  1    117.56 ? 336 ASP C C   1 -0.306 -0.095 0.051  
ATOM   8841  O  O   . ASP C 1 347 ? -32.73  -11.446 20.39   1    120.05 ? 336 ASP C O   1 -0.3   -0.105 0.051  
ATOM   8842  C  CB  . ASP C 1 347 ? -32.266 -9.1    18.736  1    109.38 ? 336 ASP C CB  1 -0.296 -0.083 0.047  
ATOM   8843  C  CG  . ASP C 1 347 ? -32.407 -8.149  17.558  1    113.66 ? 336 ASP C CG  1 -0.297 -0.075 0.044  
ATOM   8844  O  OD1 . ASP C 1 347 ? -33.469 -8.161  16.892  1    118.31 ? 336 ASP C OD1 1 -0.307 -0.075 0.042  
ATOM   8845  O  OD2 . ASP C 1 347 ? -31.448 -7.385  17.301  1    107.43 ? 336 ASP C OD2 1 -0.288 -0.068 0.043  
ATOM   8846  N  N   . GLU C 1 348 ? -33.869 -10.041 21.743  1    111.4  ? 337 GLU C N   1 -0.31  -0.092 0.054  
ATOM   8847  C  CA  . GLU C 1 348 ? -33.759 -10.934 22.89   1    110.32 ? 337 GLU C CA  1 -0.309 -0.1   0.057  
ATOM   8848  C  C   . GLU C 1 348 ? -34.548 -12.217 22.651  1    114.35 ? 337 GLU C C   1 -0.317 -0.112 0.057  
ATOM   8849  O  O   . GLU C 1 348 ? -35.724 -12.176 22.269  1    113.18 ? 337 GLU C O   1 -0.327 -0.112 0.056  
ATOM   8850  C  CB  . GLU C 1 348 ? -34.264 -10.258 24.167  1    114.61 ? 337 GLU C CB  1 -0.314 -0.094 0.06   
ATOM   8851  C  CG  . GLU C 1 348 ? -34.162 -11.149 25.426  1    108.46 ? 337 GLU C CG  1 -0.313 -0.102 0.063  
ATOM   8852  C  CD  . GLU C 1 348 ? -32.723 -11.522 25.744  1    107.78 ? 337 GLU C CD  1 -0.3   -0.106 0.064  
ATOM   8853  O  OE1 . GLU C 1 348 ? -32.007 -10.675 26.314  1    105.09 ? 337 GLU C OE1 1 -0.293 -0.098 0.066  
ATOM   8854  O  OE2 . GLU C 1 348 ? -32.293 -12.647 25.401  1    110.86 ? 337 GLU C OE2 1 -0.296 -0.116 0.063  
ATOM   8855  N  N   . THR C 1 349 ? -33.898 -13.358 22.904  1    113.59 ? 338 THR C N   1 -0.311 -0.122 0.057  
ATOM   8856  C  CA  . THR C 1 349 ? -34.533 -14.669 22.836  1    115.73 ? 338 THR C CA  1 -0.316 -0.134 0.057  
ATOM   8857  C  C   . THR C 1 349 ? -34.844 -15.258 24.204  1    120.68 ? 338 THR C C   1 -0.319 -0.14  0.06   
ATOM   8858  O  O   . THR C 1 349 ? -35.458 -16.333 24.268  1    119.06 ? 338 THR C O   1 -0.325 -0.15  0.061  
ATOM   8859  C  CB  . THR C 1 349 ? -33.634 -15.66  22.101  1    117.87 ? 338 THR C CB  1 -0.308 -0.144 0.055  
ATOM   8860  O  OG1 . THR C 1 349 ? -32.72  -16.251 23.041  1    117.64 ? 338 THR C OG1 1 -0.3   -0.149 0.058  
ATOM   8861  C  CG2 . THR C 1 349 ? -32.863 -14.951 21.023  1    111.82 ? 338 THR C CG2 1 -0.301 -0.137 0.052  
ATOM   8862  N  N   . ALA C 1 350 ? -34.412 -14.601 25.284  1    121.1  ? 339 ALA C N   1 -0.315 -0.134 0.063  
ATOM   8863  C  CA  . ALA C 1 350 ? -34.591 -15.137 26.626  1    115.43 ? 339 ALA C CA  1 -0.317 -0.139 0.066  
ATOM   8864  C  C   . ALA C 1 350 ? -36.069 -15.341 26.925  1    120.8  ? 339 ALA C C   1 -0.331 -0.141 0.067  
ATOM   8865  O  O   . ALA C 1 350 ? -36.912 -14.508 26.577  1    115.82 ? 339 ALA C O   1 -0.338 -0.133 0.066  
ATOM   8866  C  CB  . ALA C 1 350 ? -33.969 -14.199 27.66   1    112.72 ? 339 ALA C CB  1 -0.311 -0.13  0.069  
ATOM   8867  N  N   . TYR C 1 351 ? -36.375 -16.466 27.576  1    124.7  ? 340 TYR C N   1 -0.333 -0.151 0.069  
ATOM   8868  C  CA  . TYR C 1 351 ? -37.765 -16.786 27.885  1    124.39 ? 340 TYR C CA  1 -0.346 -0.154 0.07   
ATOM   8869  C  C   . TYR C 1 351 ? -38.38  -15.744 28.815  1    120.52 ? 340 TYR C C   1 -0.352 -0.144 0.072  
ATOM   8870  O  O   . TYR C 1 351 ? -39.528 -15.324 28.623  1    119.96 ? 340 TYR C O   1 -0.362 -0.14  0.071  
ATOM   8871  C  CB  . TYR C 1 351 ? -37.829 -18.191 28.482  1    122.22 ? 340 TYR C CB  1 -0.347 -0.167 0.071  
ATOM   8872  C  CG  . TYR C 1 351 ? -39.153 -18.611 29.095  1    134.89 ? 340 TYR C CG  1 -0.359 -0.171 0.073  
ATOM   8873  C  CD1 . TYR C 1 351 ? -39.477 -18.259 30.41   1    137.27 ? 340 TYR C CD1 1 -0.362 -0.167 0.076  
ATOM   8874  C  CD2 . TYR C 1 351 ? -40.055 -19.402 28.387  1    134.77 ? 340 TYR C CD2 1 -0.367 -0.178 0.071  
ATOM   8875  C  CE1 . TYR C 1 351 ? -40.673 -18.647 30.989  1    137.54 ? 340 TYR C CE1 1 -0.373 -0.171 0.077  
ATOM   8876  C  CE2 . TYR C 1 351 ? -41.257 -19.801 28.962  1    139.88 ? 340 TYR C CE2 1 -0.378 -0.181 0.072  
ATOM   8877  C  CZ  . TYR C 1 351 ? -41.56  -19.419 30.267  1    139.07 ? 340 TYR C CZ  1 -0.381 -0.178 0.076  
ATOM   8878  O  OH  . TYR C 1 351 ? -42.75  -19.802 30.849  1    137.46 ? 340 TYR C OH  1 -0.392 -0.181 0.077  
ATOM   8879  N  N   . CYS C 1 352 ? -37.624 -15.299 29.818  1    125.9  ? 341 CYS C N   1 -0.345 -0.14  0.074  
ATOM   8880  C  CA  . CYS C 1 352 ? -38.111 -14.25  30.711  1    126.22 ? 341 CYS C CA  1 -0.349 -0.131 0.077  
ATOM   8881  C  C   . CYS C 1 352 ? -38.169 -12.889 30.025  1    123.02 ? 341 CYS C C   1 -0.35  -0.118 0.075  
ATOM   8882  O  O   . CYS C 1 352 ? -38.617 -11.91  30.64   1    115.53 ? 341 CYS C O   1 -0.354 -0.109 0.077  
ATOM   8883  C  CB  . CYS C 1 352 ? -37.232 -14.17  31.964  1    115.75 ? 341 CYS C CB  1 -0.341 -0.13  0.08   
ATOM   8884  S  SG  . CYS C 1 352 ? -35.571 -13.463 31.658  1    120.31 ? 341 CYS C SG  1 -0.326 -0.123 0.079  
ATOM   8885  N  N   . GLY C 1 353 ? -37.725 -12.803 28.776  1    121.77 ? 342 GLY C N   1 -0.346 -0.117 0.072  
ATOM   8886  C  CA  . GLY C 1 353 ? -37.849 -11.57  28.033  1    122.92 ? 342 GLY C CA  1 -0.347 -0.106 0.07   
ATOM   8887  C  C   . GLY C 1 353 ? -39.04  -11.552 27.095  1    123.69 ? 342 GLY C C   1 -0.358 -0.106 0.068  
ATOM   8888  O  O   . GLY C 1 353 ? -39.824 -10.594 27.104  1    119.94 ? 342 GLY C O   1 -0.365 -0.097 0.068  
ATOM   8889  N  N   . LYS C 1 354 ? -39.2   -12.608 26.292  1    126.05 ? 343 LYS C N   1 -0.359 -0.116 0.066  
ATOM   8890  C  CA  . LYS C 1 354 ? -40.136 -12.581 25.169  1    129.26 ? 343 LYS C CA  1 -0.368 -0.115 0.063  
ATOM   8891  C  C   . LYS C 1 354 ? -41.424 -13.359 25.405  1    130.03 ? 343 LYS C C   1 -0.38  -0.122 0.063  
ATOM   8892  O  O   . LYS C 1 354 ? -42.469 -12.951 24.889  1    130.92 ? 343 LYS C O   1 -0.389 -0.119 0.062  
ATOM   8893  C  CB  . LYS C 1 354 ? -39.466 -13.123 23.9    1    122.62 ? 343 LYS C CB  1 -0.362 -0.12  0.06   
ATOM   8894  C  CG  . LYS C 1 354 ? -38.839 -12.062 23.025  1    116.66 ? 343 LYS C CG  1 -0.356 -0.111 0.057  
ATOM   8895  C  CD  . LYS C 1 354 ? -38.763 -12.575 21.609  1    128.29 ? 343 LYS C CD  1 -0.355 -0.115 0.054  
ATOM   8896  C  CE  . LYS C 1 354 ? -38.345 -11.511 20.611  1    125.01 ? 343 LYS C CE  1 -0.351 -0.105 0.051  
ATOM   8897  N  NZ  . LYS C 1 354 ? -38.182 -12.131 19.253  1    120.48 ? 343 LYS C NZ  1 -0.35  -0.111 0.048  
ATOM   8898  N  N   . PHE C 1 355 ? -41.388 -14.468 26.146  1    130.07 ? 344 PHE C N   1 -0.379 -0.133 0.065  
ATOM   8899  C  CA  . PHE C 1 355 ? -42.565 -15.319 26.284  1    135.12 ? 344 PHE C CA  1 -0.39  -0.14  0.066  
ATOM   8900  C  C   . PHE C 1 355 ? -43.713 -14.577 26.958  1    136.36 ? 344 PHE C C   1 -0.401 -0.134 0.067  
ATOM   8901  O  O   . PHE C 1 355 ? -43.677 -14.312 28.165  1    133.13 ? 344 PHE C O   1 -0.4   -0.131 0.07   
ATOM   8902  C  CB  . PHE C 1 355 ? -42.228 -16.592 27.063  1    137.24 ? 344 PHE C CB  1 -0.387 -0.152 0.068  
ATOM   8903  C  CG  . PHE C 1 355 ? -43.432 -17.426 27.4    1    138.92 ? 344 PHE C CG  1 -0.398 -0.16  0.068  
ATOM   8904  C  CD1 . PHE C 1 355 ? -44.238 -17.947 26.397  1    142.08 ? 344 PHE C CD1 1 -0.405 -0.164 0.066  
ATOM   8905  C  CD2 . PHE C 1 355 ? -43.768 -17.678 28.714  1    140.39 ? 344 PHE C CD2 1 -0.401 -0.162 0.072  
ATOM   8906  C  CE1 . PHE C 1 355 ? -45.35  -18.705 26.706  1    139.36 ? 344 PHE C CE1 1 -0.416 -0.171 0.067  
ATOM   8907  C  CE2 . PHE C 1 355 ? -44.873 -18.442 29.027  1    145.32 ? 344 PHE C CE2 1 -0.411 -0.169 0.072  
ATOM   8908  C  CZ  . PHE C 1 355 ? -45.67  -18.949 28.017  1    144.58 ? 344 PHE C CZ  1 -0.419 -0.174 0.07   
ATOM   8909  N  N   . VAL C 1 356 ? -44.746 -14.249 26.182  1    135.83 ? 345 VAL C N   1 -0.41  -0.131 0.065  
ATOM   8910  C  CA  . VAL C 1 356 ? -45.885 -13.479 26.665  1    136.84 ? 345 VAL C CA  1 -0.42  -0.124 0.067  
ATOM   8911  C  C   . VAL C 1 356 ? -47.177 -14.205 26.316  1    144.55 ? 345 VAL C C   1 -0.432 -0.13  0.066  
ATOM   8912  O  O   . VAL C 1 356 ? -47.357 -14.648 25.174  1    145.26 ? 345 VAL C O   1 -0.434 -0.134 0.063  
ATOM   8913  C  CB  . VAL C 1 356 ? -45.92  -12.063 26.066  1    132.52 ? 345 VAL C CB  1 -0.421 -0.111 0.065  
ATOM   8914  C  CG1 . VAL C 1 356 ? -47.097 -11.336 26.627  1    126.5  ? 345 VAL C CG1 1 -0.432 -0.104 0.066  
ATOM   8915  C  CG2 . VAL C 1 356 ? -44.642 -11.314 26.356  1    132.16 ? 345 VAL C CG2 1 -0.409 -0.104 0.066  
ATOM   8916  N  N   . ASN C 1 357 ? -48.08  -14.305 27.301  1    145.15 ? 346 ASN C N   1 -0.441 -0.131 0.068  
ATOM   8917  C  CA  . ASN C 1 357 ? -49.481 -14.704 27.089  1    145.64 ? 346 ASN C CA  1 -0.453 -0.135 0.068  
ATOM   8918  C  C   . ASN C 1 357 ? -49.607 -16.005 26.297  1    148    ? 346 ASN C C   1 -0.455 -0.147 0.066  
ATOM   8919  O  O   . ASN C 1 357 ? -50.582 -16.209 25.566  1    151.65 ? 346 ASN C O   1 -0.464 -0.149 0.064  
ATOM   8920  C  CB  . ASN C 1 357 ? -50.284 -13.581 26.414  1    139.48 ? 346 ASN C CB  1 -0.461 -0.124 0.066  
ATOM   8921  C  CG  . ASN C 1 357 ? -50.65  -12.454 27.38   1    141.6  ? 346 ASN C CG  1 -0.464 -0.114 0.068  
ATOM   8922  O  OD1 . ASN C 1 357 ? -50.501 -11.268 27.066  1    130.61 ? 346 ASN C OD1 1 -0.463 -0.103 0.068  
ATOM   8923  N  ND2 . ASN C 1 357 ? -51.128 -12.827 28.568  1    146.94 ? 346 ASN C ND2 1 -0.469 -0.118 0.071  
ATOM   8924  N  N   . GLY C 1 358 ? -48.62  -16.894 26.429  1    145.8  ? 347 GLY C N   1 -0.446 -0.155 0.066  
ATOM   8925  C  CA  . GLY C 1 358 ? -48.715 -18.236 25.892  1    148.35 ? 347 GLY C CA  1 -0.446 -0.167 0.065  
ATOM   8926  C  C   . GLY C 1 358 ? -47.79  -18.564 24.735  1    151.64 ? 347 GLY C C   1 -0.438 -0.17  0.062  
ATOM   8927  O  O   . GLY C 1 358 ? -47.711 -19.741 24.364  1    155.01 ? 347 GLY C O   1 -0.437 -0.181 0.061  
ATOM   8928  N  N   . ARG C 1 359 ? -47.085 -17.592 24.15   1    149.37 ? 348 ARG C N   1 -0.431 -0.161 0.06   
ATOM   8929  C  CA  . ARG C 1 359 ? -46.158 -17.9   23.064  1    147.11 ? 348 ARG C CA  1 -0.423 -0.164 0.058  
ATOM   8930  C  C   . ARG C 1 359 ? -44.967 -16.953 23.102  1    140.63 ? 348 ARG C C   1 -0.412 -0.155 0.058  
ATOM   8931  O  O   . ARG C 1 359 ? -45.021 -15.874 23.7    1    137.43 ? 348 ARG C O   1 -0.413 -0.145 0.059  
ATOM   8932  C  CB  . ARG C 1 359 ? -46.826 -17.846 21.672  1    147.36 ? 348 ARG C CB  1 -0.429 -0.164 0.054  
ATOM   8933  C  CG  . ARG C 1 359 ? -47.808 -16.699 21.42   1    152.06 ? 348 ARG C CG  1 -0.438 -0.153 0.053  
ATOM   8934  C  CD  . ARG C 1 359 ? -49.185 -17.039 21.991  1    161.43 ? 348 ARG C CD  1 -0.451 -0.156 0.055  
ATOM   8935  N  NE  . ARG C 1 359 ? -50.297 -16.395 21.301  1    171.06 ? 348 ARG C NE  1 -0.461 -0.15  0.053  
ATOM   8936  C  CZ  . ARG C 1 359 ? -51.575 -16.652 21.555  1    173.84 ? 348 ARG C CZ  1 -0.473 -0.153 0.054  
ATOM   8937  N  NH1 . ARG C 1 359 ? -51.933 -17.529 22.482  1    172.66 ? 348 ARG C NH1 1 -0.476 -0.161 0.056  
ATOM   8938  N  NH2 . ARG C 1 359 ? -52.517 -16.015 20.862  1    168.28 ? 348 ARG C NH2 1 -0.481 -0.147 0.052  
ATOM   8939  N  N   . MET C 1 360 ? -43.878 -17.384 22.465  1    138.65 ? 349 MET C N   1 -0.402 -0.159 0.056  
ATOM   8940  C  CA  . MET C 1 360 ? -42.741 -16.503 22.255  1    133.85 ? 349 MET C CA  1 -0.392 -0.151 0.056  
ATOM   8941  C  C   . MET C 1 360 ? -43.145 -15.395 21.29   1    132.84 ? 349 MET C C   1 -0.395 -0.141 0.053  
ATOM   8942  O  O   . MET C 1 360 ? -43.72  -15.658 20.23   1    133.96 ? 349 MET C O   1 -0.401 -0.143 0.051  
ATOM   8943  C  CB  . MET C 1 360 ? -41.546 -17.288 21.712  1    130.82 ? 349 MET C CB  1 -0.381 -0.158 0.054  
ATOM   8944  C  CG  . MET C 1 360 ? -40.223 -16.973 22.404  1    130.18 ? 349 MET C CG  1 -0.369 -0.156 0.056  
ATOM   8945  S  SD  . MET C 1 360 ? -40.214 -17.454 24.149  1    137.83 ? 349 MET C SD  1 -0.369 -0.16  0.06   
ATOM   8946  C  CE  . MET C 1 360 ? -39.651 -19.158 24.064  1    130.43 ? 349 MET C CE  1 -0.363 -0.176 0.06   
ATOM   8947  N  N   . MET C 1 361 ? -42.864 -14.152 21.673  1    130.32 ? 350 MET C N   1 -0.393 -0.13  0.054  
ATOM   8948  C  CA  . MET C 1 361 ? -43.343 -12.995 20.924  1    128.67 ? 350 MET C CA  1 -0.397 -0.119 0.052  
ATOM   8949  C  C   . MET C 1 361 ? -42.732 -12.945 19.525  1    131.78 ? 350 MET C C   1 -0.392 -0.119 0.049  
ATOM   8950  O  O   . MET C 1 361 ? -41.518 -13.096 19.353  1    131.32 ? 350 MET C O   1 -0.38  -0.12  0.048  
ATOM   8951  C  CB  . MET C 1 361 ? -43.009 -11.728 21.7    1    126.01 ? 350 MET C CB  1 -0.394 -0.107 0.054  
ATOM   8952  C  CG  . MET C 1 361 ? -43.679 -10.479 21.195  1    127.22 ? 350 MET C CG  1 -0.4   -0.096 0.053  
ATOM   8953  S  SD  . MET C 1 361 ? -43.067 -9.052  22.122  1    135.47 ? 350 MET C SD  1 -0.395 -0.083 0.055  
ATOM   8954  C  CE  . MET C 1 361 ? -44.33  -8.831  23.364  1    127.39 ? 350 MET C CE  1 -0.406 -0.081 0.058  
ATOM   8955  N  N   . GLY C 1 362 ? -43.585 -12.713 18.517  1    131.56 ? 351 GLY C N   1 -0.399 -0.117 0.046  
ATOM   8956  C  CA  . GLY C 1 362 ? -43.151 -12.747 17.136  1    125.35 ? 351 GLY C CA  1 -0.395 -0.117 0.043  
ATOM   8957  C  C   . GLY C 1 362 ? -42.404 -11.497 16.706  1    126.39 ? 351 GLY C C   1 -0.389 -0.105 0.042  
ATOM   8958  O  O   . GLY C 1 362 ? -42.384 -10.483 17.402  1    127.09 ? 351 GLY C O   1 -0.388 -0.096 0.043  
ATOM   8959  N  N   . LYS C 1 363 ? -41.785 -11.595 15.524  1    127.01 ? 352 LYS C N   1 -0.383 -0.106 0.039  
ATOM   8960  C  CA  . LYS C 1 363 ? -40.999 -10.521 14.92   1    130.14 ? 352 LYS C CA  1 -0.376 -0.096 0.037  
ATOM   8961  C  C   . LYS C 1 363 ? -41.688 -9.161  15      1    130.48 ? 352 LYS C C   1 -0.382 -0.084 0.037  
ATOM   8962  O  O   . LYS C 1 363 ? -41.195 -8.24   15.662  1    123.77 ? 352 LYS C O   1 -0.378 -0.076 0.039  
ATOM   8963  C  CB  . LYS C 1 363 ? -40.692 -10.839 13.443  1    126.1  ? 352 LYS C CB  1 -0.373 -0.099 0.034  
ATOM   8964  C  CG  . LYS C 1 363 ? -39.516 -11.786 13.194  1    122.11 ? 352 LYS C CG  1 -0.362 -0.108 0.033  
ATOM   8965  C  CD  . LYS C 1 363 ? -38.179 -11.218 13.694  1    120.57 ? 352 LYS C CD  1 -0.35  -0.103 0.034  
ATOM   8966  C  CE  . LYS C 1 363 ? -37.901 -9.794  13.191  1    127.81 ? 352 LYS C CE  1 -0.347 -0.09  0.033  
ATOM   8967  N  NZ  . LYS C 1 363 ? -37.96  -9.64   11.704  1    125.19 ? 352 LYS C NZ  1 -0.348 -0.088 0.029  
ATOM   8968  N  N   . THR C 1 364 ? -42.824 -9.021  14.311  1    135.71 ? 353 THR C N   1 -0.392 -0.083 0.036  
ATOM   8969  C  CA  . THR C 1 364 ? -43.471 -7.718  14.207  1    133.77 ? 353 THR C CA  1 -0.398 -0.071 0.035  
ATOM   8970  C  C   . THR C 1 364 ? -44.048 -7.263  15.537  1    130.41 ? 353 THR C C   1 -0.404 -0.067 0.039  
ATOM   8971  O  O   . THR C 1 364 ? -44.173 -6.056  15.767  1    136.02 ? 353 THR C O   1 -0.405 -0.055 0.039  
ATOM   8972  C  CB  . THR C 1 364 ? -44.577 -7.753  13.155  1    136.66 ? 353 THR C CB  1 -0.409 -0.071 0.033  
ATOM   8973  O  OG1 . THR C 1 364 ? -45.763 -8.3    13.749  1    136.7  ? 353 THR C OG1 1 -0.419 -0.076 0.034  
ATOM   8974  C  CG2 . THR C 1 364 ? -44.15  -8.609  11.95   1    124.06 ? 353 THR C CG2 1 -0.405 -0.079 0.03   
ATOM   8975  N  N   . ALA C 1 365 ? -44.427 -8.203  16.409  1    131.24 ? 354 ALA C N   1 -0.407 -0.075 0.041  
ATOM   8976  C  CA  . ALA C 1 365 ? -44.862 -7.853  17.762  1    131.02 ? 354 ALA C CA  1 -0.411 -0.072 0.044  
ATOM   8977  C  C   . ALA C 1 365 ? -43.71  -7.279  18.58   1    124.85 ? 354 ALA C C   1 -0.401 -0.067 0.046  
ATOM   8978  O  O   . ALA C 1 365 ? -43.782 -6.147  19.073  1    121.49 ? 354 ALA C O   1 -0.401 -0.056 0.048  
ATOM   8979  C  CB  . ALA C 1 365 ? -45.45  -9.08   18.463  1    129.83 ? 354 ALA C CB  1 -0.417 -0.083 0.046  
ATOM   8980  N  N   . ALA C 1 366 ? -42.628 -8.057  18.725  1    125.69 ? 355 ALA C N   1 -0.391 -0.074 0.047  
ATOM   8981  C  CA  . ALA C 1 366 ? -41.447 -7.618  19.464  1    123    ? 355 ALA C CA  1 -0.38  -0.07  0.049  
ATOM   8982  C  C   . ALA C 1 366 ? -40.824 -6.353  18.889  1    122.01 ? 355 ALA C C   1 -0.374 -0.058 0.047  
ATOM   8983  O  O   . ALA C 1 366 ? -40.032 -5.704  19.575  1    119.88 ? 355 ALA C O   1 -0.367 -0.052 0.049  
ATOM   8984  C  CB  . ALA C 1 366 ? -40.401 -8.737  19.5    1    118.35 ? 355 ALA C CB  1 -0.37  -0.08  0.049  
ATOM   8985  N  N   . HIS C 1 367 ? -41.139 -5.996  17.646  1    131.42 ? 356 HIS C N   1 -0.377 -0.055 0.044  
ATOM   8986  C  CA  . HIS C 1 367 ? -40.697 -4.712  17.12   1    131.55 ? 356 HIS C CA  1 -0.373 -0.043 0.043  
ATOM   8987  C  C   . HIS C 1 367 ? -41.369 -3.552  17.839  1    131.98 ? 356 HIS C C   1 -0.379 -0.033 0.045  
ATOM   8988  O  O   . HIS C 1 367 ? -40.82  -2.443  17.855  1    132.27 ? 356 HIS C O   1 -0.374 -0.022 0.045  
ATOM   8989  C  CB  . HIS C 1 367 ? -40.983 -4.625  15.615  1    131.4  ? 356 HIS C CB  1 -0.376 -0.042 0.039  
ATOM   8990  C  CG  . HIS C 1 367 ? -40.643 -3.297  15.008  1    137.42 ? 356 HIS C CG  1 -0.372 -0.03  0.037  
ATOM   8991  N  ND1 . HIS C 1 367 ? -41.126 -2.099  15.497  1    133.49 ? 356 HIS C ND1 1 -0.377 -0.019 0.039  
ATOM   8992  C  CD2 . HIS C 1 367 ? -39.874 -2.98   13.94   1    148.55 ? 356 HIS C CD2 1 -0.365 -0.027 0.035  
ATOM   8993  C  CE1 . HIS C 1 367 ? -40.658 -1.103  14.77   1    135.43 ? 356 HIS C CE1 1 -0.373 -0.01  0.037  
ATOM   8994  N  NE2 . HIS C 1 367 ? -39.9   -1.611  13.814  1    151.73 ? 356 HIS C NE2 1 -0.366 -0.015 0.034  
ATOM   8995  N  N   . GLN C 1 368 ? -42.553 -3.77   18.404  1    128.27 ? 357 GLN C N   1 -0.39  -0.035 0.046  
ATOM   8996  C  CA  . GLN C 1 368 ? -43.35  -2.674  18.931  1    129.7  ? 357 GLN C CA  1 -0.397 -0.025 0.047  
ATOM   8997  C  C   . GLN C 1 368 ? -43.192 -2.481  20.436  1    126.94 ? 357 GLN C C   1 -0.396 -0.023 0.051  
ATOM   8998  O  O   . GLN C 1 368 ? -43.123 -1.336  20.902  1    126.19 ? 357 GLN C O   1 -0.395 -0.012 0.052  
ATOM   8999  C  CB  . GLN C 1 368 ? -44.827 -2.891  18.592  1    129.43 ? 357 GLN C CB  1 -0.411 -0.026 0.046  
ATOM   9000  C  CG  . GLN C 1 368 ? -45.77  -2.172  19.543  1    131.78 ? 357 GLN C CG  1 -0.419 -0.02  0.049  
ATOM   9001  C  CD  . GLN C 1 368 ? -47.125 -1.906  18.934  1    135.02 ? 357 GLN C CD  1 -0.432 -0.017 0.047  
ATOM   9002  O  OE1 . GLN C 1 368 ? -47.319 -2.06   17.72   1    126.09 ? 357 GLN C OE1 1 -0.434 -0.019 0.044  
ATOM   9003  N  NE2 . GLN C 1 368 ? -48.08  -1.497  19.776  1    131.54 ? 357 GLN C NE2 1 -0.441 -0.014 0.049  
ATOM   9004  N  N   . PHE C 1 369 ? -43.129 -3.566  21.209  1    126.05 ? 358 PHE C N   1 -0.395 -0.033 0.053  
ATOM   9005  C  CA  . PHE C 1 369 ? -43.012 -3.479  22.656  1    119.98 ? 358 PHE C CA  1 -0.394 -0.032 0.057  
ATOM   9006  C  C   . PHE C 1 369 ? -41.575 -3.656  23.146  1    117.61 ? 358 PHE C C   1 -0.381 -0.034 0.058  
ATOM   9007  O  O   . PHE C 1 369 ? -41.354 -3.754  24.353  1    117.56 ? 358 PHE C O   1 -0.379 -0.034 0.061  
ATOM   9008  C  CB  . PHE C 1 369 ? -43.933 -4.506  23.316  1    119.78 ? 358 PHE C CB  1 -0.403 -0.041 0.058  
ATOM   9009  C  CG  . PHE C 1 369 ? -45.309 -4.552  22.714  1    122.18 ? 358 PHE C CG  1 -0.415 -0.042 0.057  
ATOM   9010  C  CD1 . PHE C 1 369 ? -46.246 -3.576  23.012  1    118.84 ? 358 PHE C CD1 1 -0.424 -0.033 0.057  
ATOM   9011  C  CD2 . PHE C 1 369 ? -45.661 -5.573  21.836  1    127.98 ? 358 PHE C CD2 1 -0.418 -0.051 0.055  
ATOM   9012  C  CE1 . PHE C 1 369 ? -47.516 -3.618  22.442  1    125.04 ? 358 PHE C CE1 1 -0.435 -0.033 0.056  
ATOM   9013  C  CE2 . PHE C 1 369 ? -46.929 -5.622  21.261  1    125.26 ? 358 PHE C CE2 1 -0.43  -0.052 0.053  
ATOM   9014  C  CZ  . PHE C 1 369 ? -47.856 -4.644  21.565  1    125.71 ? 358 PHE C CZ  1 -0.439 -0.043 0.054  
ATOM   9015  N  N   . ARG C 1 370 ? -40.594 -3.705  22.244  1    118.1  ? 359 ARG C N   1 -0.372 -0.034 0.056  
ATOM   9016  C  CA  . ARG C 1 370 ? -39.191 -3.713  22.645  1    110.25 ? 359 ARG C CA  1 -0.359 -0.034 0.057  
ATOM   9017  C  C   . ARG C 1 370 ? -38.425 -2.592  21.959  1    106.66 ? 359 ARG C C   1 -0.352 -0.024 0.055  
ATOM   9018  O  O   . ARG C 1 370 ? -39.013 -1.732  21.291  1    108.79 ? 359 ARG C O   1 -0.358 -0.016 0.053  
ATOM   9019  C  CB  . ARG C 1 370 ? -38.537 -5.053  22.327  1    109.79 ? 359 ARG C CB  1 -0.353 -0.046 0.056  
ATOM   9020  C  CG  . ARG C 1 370 ? -39.143 -6.218  23.064  1    115.15 ? 359 ARG C CG  1 -0.359 -0.057 0.058  
ATOM   9021  C  CD  . ARG C 1 370 ? -38.71  -6.262  24.518  1    107.35 ? 359 ARG C CD  1 -0.355 -0.057 0.061  
ATOM   9022  N  NE  . ARG C 1 370 ? -39.374 -7.346  25.23   1    112.25 ? 359 ARG C NE  1 -0.361 -0.067 0.063  
ATOM   9023  C  CZ  . ARG C 1 370 ? -40.638 -7.311  25.64   1    118.68 ? 359 ARG C CZ  1 -0.372 -0.067 0.064  
ATOM   9024  N  NH1 . ARG C 1 370 ? -41.432 -6.29   25.359  1    114.53 ? 359 ARG C NH1 1 -0.38  -0.058 0.063  
ATOM   9025  N  NH2 . ARG C 1 370 ? -41.113 -8.319  26.365  1    122.98 ? 359 ARG C NH2 1 -0.377 -0.076 0.066  
ATOM   9026  N  N   . PHE C 1 371 ? -37.109 -2.607  22.112  1    101.84 ? 360 PHE C N   1 -0.34  -0.024 0.055  
ATOM   9027  C  CA  . PHE C 1 371 ? -36.245 -1.549  21.621  1    108.78 ? 360 PHE C CA  1 -0.332 -0.014 0.054  
ATOM   9028  C  C   . PHE C 1 371 ? -35.375 -2.072  20.485  1    106.89 ? 360 PHE C C   1 -0.324 -0.019 0.051  
ATOM   9029  O  O   . PHE C 1 371 ? -35.221 -3.281  20.304  1    109.04 ? 360 PHE C O   1 -0.323 -0.03  0.051  
ATOM   9030  C  CB  . PHE C 1 371 ? -35.361 -1.013  22.759  1    109.58 ? 360 PHE C CB  1 -0.324 -0.009 0.057  
ATOM   9031  C  CG  . PHE C 1 371 ? -36.128 -0.55   23.954  1    101.22 ? 360 PHE C CG  1 -0.331 -0.005 0.06   
ATOM   9032  C  CD1 . PHE C 1 371 ? -37.321 0.129   23.801  1    105.7  ? 360 PHE C CD1 1 -0.342 0.001  0.059  
ATOM   9033  C  CD2 . PHE C 1 371 ? -35.666 -0.812  25.232  1    108.39 ? 360 PHE C CD2 1 -0.327 -0.007 0.063  
ATOM   9034  C  CE1 . PHE C 1 371 ? -38.039 0.552   24.899  1    113.42 ? 360 PHE C CE1 1 -0.349 0.005  0.062  
ATOM   9035  C  CE2 . PHE C 1 371 ? -36.379 -0.393  26.349  1    105.48 ? 360 PHE C CE2 1 -0.333 -0.004 0.066  
ATOM   9036  C  CZ  . PHE C 1 371 ? -37.569 0.288   26.185  1    107.6  ? 360 PHE C CZ  1 -0.344 0.003  0.065  
ATOM   9037  N  N   . ASN C 1 372 ? -34.791 -1.149  19.727  1    97.82  ? 361 ASN C N   1 -0.319 -0.011 0.049  
ATOM   9038  C  CA  . ASN C 1 372 ? -33.787 -1.509  18.74   1    105.4  ? 361 ASN C CA  1 -0.31  -0.014 0.047  
ATOM   9039  C  C   . ASN C 1 372 ? -32.576 -0.603  18.91   1    104.04 ? 361 ASN C C   1 -0.299 -0.006 0.047  
ATOM   9040  O  O   . ASN C 1 372 ? -32.63  0.418   19.601  1    100.03 ? 361 ASN C O   1 -0.299 0.004  0.049  
ATOM   9041  C  CB  . ASN C 1 372 ? -34.337 -1.429  17.298  1    108.7  ? 361 ASN C CB  1 -0.315 -0.013 0.043  
ATOM   9042  C  CG  . ASN C 1 372 ? -34.886 -0.048  16.952  1    103.58 ? 361 ASN C CG  1 -0.32  -0.0   0.042  
ATOM   9043  O  OD1 . ASN C 1 372 ? -34.144 0.933   16.902  1    103.11 ? 361 ASN C OD1 1 -0.313 0.009  0.042  
ATOM   9044  N  ND2 . ASN C 1 372 ? -36.192 0.031   16.724  1    102.63 ? 361 ASN C ND2 1 -0.332 0.0    0.042  
ATOM   9045  N  N   . ASP C 1 373 ? -31.479 -0.999  18.244  1    106.22 ? 362 ASP C N   1 -0.288 -0.009 0.046  
ATOM   9046  C  CA  . ASP C 1 373 ? -30.237 -0.224  18.241  1    107.03 ? 362 ASP C CA  1 -0.277 -0.002 0.046  
ATOM   9047  C  C   . ASP C 1 373 ? -30.478 1.267   18.036  1    106.59 ? 362 ASP C C   1 -0.279 0.012  0.045  
ATOM   9048  O  O   . ASP C 1 373 ? -29.74  2.096   18.584  1    108.57 ? 362 ASP C O   1 -0.273 0.019  0.046  
ATOM   9049  C  CB  . ASP C 1 373 ? -29.297 -0.737  17.147  1    106.66 ? 362 ASP C CB  1 -0.268 -0.007 0.043  
ATOM   9050  C  CG  . ASP C 1 373 ? -29.009 -2.226  17.269  1    107.65 ? 362 ASP C CG  1 -0.266 -0.02  0.043  
ATOM   9051  O  OD1 . ASP C 1 373 ? -29.411 -2.825  18.292  1    110.74 ? 362 ASP C OD1 1 -0.27  -0.026 0.046  
ATOM   9052  O  OD2 . ASP C 1 373 ? -28.375 -2.799  16.35   1    104.19 ? 362 ASP C OD2 1 -0.26  -0.026 0.041  
ATOM   9053  N  N   . GLY C 1 374 ? -31.495 1.629   17.253  1    103.02 ? 363 GLY C N   1 -0.289 0.015  0.043  
ATOM   9054  C  CA  . GLY C 1 374 ? -31.842 3.034   17.115  1    106.41 ? 363 GLY C CA  1 -0.292 0.028  0.043  
ATOM   9055  C  C   . GLY C 1 374 ? -32.203 3.683   18.438  1    107.24 ? 363 GLY C C   1 -0.295 0.034  0.046  
ATOM   9056  O  O   . GLY C 1 374 ? -31.675 4.743   18.79   1    108.32 ? 363 GLY C O   1 -0.29  0.043  0.047  
ATOM   9057  N  N   . ASP C 1 375 ? -33.104 3.051   19.197  1    107.1  ? 364 ASP C N   1 -0.303 0.028  0.048  
ATOM   9058  C  CA  . ASP C 1 375 ? -33.535 3.621   20.475  1    112.86 ? 364 ASP C CA  1 -0.307 0.033  0.051  
ATOM   9059  C  C   . ASP C 1 375 ? -32.382 3.698   21.476  1    106.58 ? 364 ASP C C   1 -0.297 0.034  0.054  
ATOM   9060  O  O   . ASP C 1 375 ? -32.087 4.766   22.027  1    102.31 ? 364 ASP C O   1 -0.294 0.044  0.055  
ATOM   9061  C  CB  . ASP C 1 375 ? -34.691 2.808   21.063  1    111.38 ? 364 ASP C CB  1 -0.318 0.026  0.053  
ATOM   9062  C  CG  . ASP C 1 375 ? -35.704 2.384   20.02   1    113.39 ? 364 ASP C CG  1 -0.327 0.022  0.05   
ATOM   9063  O  OD1 . ASP C 1 375 ? -35.564 1.248   19.51   1    113.27 ? 364 ASP C OD1 1 -0.326 0.011  0.049  
ATOM   9064  O  OD2 . ASP C 1 375 ? -36.632 3.181   19.718  1    116.58 ? 364 ASP C OD2 1 -0.336 0.029  0.049  
ATOM   9065  N  N   . LEU C 1 376 ? -31.719 2.563   21.728  1    103.05 ? 365 LEU C N   1 -0.291 0.023  0.054  
ATOM   9066  C  CA  . LEU C 1 376 ? -30.627 2.561   22.698  1    99.41  ? 365 LEU C CA  1 -0.281 0.023  0.057  
ATOM   9067  C  C   . LEU C 1 376 ? -29.5   3.481   22.255  1    102.42 ? 365 LEU C C   1 -0.27  0.032  0.056  
ATOM   9068  O  O   . LEU C 1 376 ? -28.949 4.228   23.074  1    103.19 ? 365 LEU C O   1 -0.265 0.039  0.058  
ATOM   9069  C  CB  . LEU C 1 376 ? -30.096 1.146   22.915  1    94.93  ? 365 LEU C CB  1 -0.276 0.011  0.057  
ATOM   9070  C  CG  . LEU C 1 376 ? -31.102 -0.001  23.076  1    91.95  ? 365 LEU C CG  1 -0.285 -0.0   0.058  
ATOM   9071  C  CD1 . LEU C 1 376 ? -30.366 -1.238  23.577  1    84.69  ? 365 LEU C CD1 1 -0.278 -0.011 0.059  
ATOM   9072  C  CD2 . LEU C 1 376 ? -32.326 0.327   23.947  1    85.29  ? 365 LEU C CD2 1 -0.296 0.003  0.06   
ATOM   9073  N  N   . GLY C 1 377 ? -29.142 3.438   20.965  1    106.28 ? 366 GLY C N   1 -0.267 0.032  0.052  
ATOM   9074  C  CA  . GLY C 1 377 ? -28.173 4.388   20.439  1    102.78 ? 366 GLY C CA  1 -0.258 0.04   0.051  
ATOM   9075  C  C   . GLY C 1 377 ? -28.514 5.815   20.81   1    107.89 ? 366 GLY C C   1 -0.261 0.053  0.052  
ATOM   9076  O  O   . GLY C 1 377 ? -27.703 6.527   21.411  1    106.41 ? 366 GLY C O   1 -0.254 0.06   0.053  
ATOM   9077  N  N   . TYR C 1 378 ? -29.741 6.243   20.493  1    109.79 ? 367 TYR C N   1 -0.273 0.057  0.051  
ATOM   9078  C  CA  . TYR C 1 378 ? -30.179 7.596   20.834  1    106.74 ? 367 TYR C CA  1 -0.277 0.07   0.052  
ATOM   9079  C  C   . TYR C 1 378 ? -30.052 7.854   22.329  1    106.06 ? 367 TYR C C   1 -0.275 0.072  0.056  
ATOM   9080  O  O   . TYR C 1 378 ? -29.475 8.864   22.754  1    107.85 ? 367 TYR C O   1 -0.27  0.081  0.057  
ATOM   9081  C  CB  . TYR C 1 378 ? -31.624 7.805   20.381  1    102.8  ? 367 TYR C CB  1 -0.29  0.072  0.051  
ATOM   9082  C  CG  . TYR C 1 378 ? -32.021 9.249   20.33   1    100.34 ? 367 TYR C CG  1 -0.293 0.085  0.051  
ATOM   9083  C  CD1 . TYR C 1 378 ? -31.233 10.17   19.658  1    104.74 ? 367 TYR C CD1 1 -0.286 0.093  0.049  
ATOM   9084  C  CD2 . TYR C 1 378 ? -33.182 9.695   20.938  1    100.42 ? 367 TYR C CD2 1 -0.304 0.089  0.052  
ATOM   9085  C  CE1 . TYR C 1 378 ? -31.585 11.504  19.591  1    109.48 ? 367 TYR C CE1 1 -0.289 0.105  0.049  
ATOM   9086  C  CE2 . TYR C 1 378 ? -33.548 11.032  20.886  1    107.52 ? 367 TYR C CE2 1 -0.307 0.101  0.052  
ATOM   9087  C  CZ  . TYR C 1 378 ? -32.744 11.936  20.208  1    112.4  ? 367 TYR C CZ  1 -0.3   0.109  0.05   
ATOM   9088  O  OH  . TYR C 1 378 ? -33.097 13.274  20.142  1    114    ? 367 TYR C OH  1 -0.303 0.122  0.05   
ATOM   9089  N  N   . PHE C 1 379 ? -30.591 6.942   23.137  1    107.62 ? 368 PHE C N   1 -0.28  0.064  0.058  
ATOM   9090  C  CA  . PHE C 1 379 ? -30.594 7.003   24.595  1    103.76 ? 368 PHE C CA  1 -0.28  0.064  0.061  
ATOM   9091  C  C   . PHE C 1 379 ? -29.227 7.382   25.154  1    101.67 ? 368 PHE C C   1 -0.268 0.068  0.063  
ATOM   9092  O  O   . PHE C 1 379 ? -29.049 8.479   25.699  1    97.91  ? 368 PHE C O   1 -0.266 0.078  0.064  
ATOM   9093  C  CB  . PHE C 1 379 ? -31.028 5.645   25.13   1    101.58 ? 368 PHE C CB  1 -0.284 0.052  0.063  
ATOM   9094  C  CG  . PHE C 1 379 ? -31.562 5.675   26.518  1    111.61 ? 368 PHE C CG  1 -0.289 0.052  0.066  
ATOM   9095  C  CD1 . PHE C 1 379 ? -32.912 5.88    26.74   1    110.72 ? 368 PHE C CD1 1 -0.302 0.054  0.067  
ATOM   9096  C  CD2 . PHE C 1 379 ? -30.714 5.466   27.609  1    109.19 ? 368 PHE C CD2 1 -0.281 0.05   0.069  
ATOM   9097  C  CE1 . PHE C 1 379 ? -33.402 5.891   28.025  1    110.38 ? 368 PHE C CE1 1 -0.306 0.054  0.07   
ATOM   9098  C  CE2 . PHE C 1 379 ? -31.193 5.484   28.886  1    102.47 ? 368 PHE C CE2 1 -0.286 0.05   0.072  
ATOM   9099  C  CZ  . PHE C 1 379 ? -32.541 5.693   29.102  1    110.94 ? 368 PHE C CZ  1 -0.298 0.052  0.073  
ATOM   9100  N  N   . TYR C 1 380 ? -28.253 6.478   24.976  1    101.74 ? 369 TYR C N   1 -0.259 0.059  0.062  
ATOM   9101  C  CA  . TYR C 1 380 ? -26.9   6.705   25.479  1    103.03 ? 369 TYR C CA  1 -0.247 0.061  0.064  
ATOM   9102  C  C   . TYR C 1 380 ? -26.313 8       24.934  1    105.25 ? 369 TYR C C   1 -0.241 0.073  0.062  
ATOM   9103  O  O   . TYR C 1 380 ? -25.726 8.782   25.693  1    104.64 ? 369 TYR C O   1 -0.236 0.08   0.064  
ATOM   9104  C  CB  . TYR C 1 380 ? -26.008 5.501   25.147  1    103.47 ? 369 TYR C CB  1 -0.238 0.05   0.063  
ATOM   9105  C  CG  . TYR C 1 380 ? -26.486 4.244   25.854  1    105.93 ? 369 TYR C CG  1 -0.243 0.039  0.065  
ATOM   9106  C  CD1 . TYR C 1 380 ? -27.036 4.335   27.126  1    102.88 ? 369 TYR C CD1 1 -0.248 0.04   0.068  
ATOM   9107  C  CD2 . TYR C 1 380 ? -26.441 2.987   25.236  1    102.79 ? 369 TYR C CD2 1 -0.242 0.027  0.063  
ATOM   9108  C  CE1 . TYR C 1 380 ? -27.508 3.232   27.776  1    107.86 ? 369 TYR C CE1 1 -0.252 0.03   0.069  
ATOM   9109  C  CE2 . TYR C 1 380 ? -26.908 1.862   25.879  1    101.35 ? 369 TYR C CE2 1 -0.247 0.017  0.065  
ATOM   9110  C  CZ  . TYR C 1 380 ? -27.442 1.994   27.161  1    114.43 ? 369 TYR C CZ  1 -0.251 0.018  0.068  
ATOM   9111  O  OH  . TYR C 1 380 ? -27.922 0.891   27.841  1    115.15 ? 369 TYR C OH  1 -0.256 0.008  0.07   
ATOM   9112  N  N   . GLU C 1 381 ? -26.49  8.264   23.63   1    106.5  ? 370 GLU C N   1 -0.243 0.076  0.059  
ATOM   9113  C  CA  . GLU C 1 381 ? -26.077 9.552   23.077  1    106.44 ? 370 GLU C CA  1 -0.239 0.088  0.058  
ATOM   9114  C  C   . GLU C 1 381 ? -26.761 10.704  23.804  1    102.63 ? 370 GLU C C   1 -0.245 0.098  0.059  
ATOM   9115  O  O   . GLU C 1 381 ? -26.108 11.69   24.172  1    101.08 ? 370 GLU C O   1 -0.239 0.107  0.06   
ATOM   9116  C  CB  . GLU C 1 381 ? -26.375 9.61    21.576  1    101.26 ? 370 GLU C CB  1 -0.242 0.088  0.054  
ATOM   9117  C  CG  . GLU C 1 381 ? -25.188 9.249   20.691  1    107.03 ? 370 GLU C CG  1 -0.231 0.085  0.052  
ATOM   9118  C  CD  . GLU C 1 381 ? -24.168 10.379  20.588  1    114.67 ? 370 GLU C CD  1 -0.221 0.095  0.051  
ATOM   9119  O  OE1 . GLU C 1 381 ? -24.379 11.424  21.26   1    106.42 ? 370 GLU C OE1 1 -0.223 0.105  0.053  
ATOM   9120  O  OE2 . GLU C 1 381 ? -23.169 10.222  19.824  1    117.66 ? 370 GLU C OE2 1 -0.212 0.094  0.049  
ATOM   9121  N  N   . SER C 1 382 ? -28.068 10.583  24.048  1    100.17 ? 371 SER C N   1 -0.257 0.097  0.06   
ATOM   9122  C  CA  . SER C 1 382 ? -28.811 11.66   24.696  1    102.95 ? 371 SER C CA  1 -0.264 0.107  0.062  
ATOM   9123  C  C   . SER C 1 382 ? -28.362 11.842  26.145  1    105.32 ? 371 SER C C   1 -0.26  0.109  0.065  
ATOM   9124  O  O   . SER C 1 382 ? -27.907 12.929  26.533  1    104.91 ? 371 SER C O   1 -0.256 0.118  0.066  
ATOM   9125  C  CB  . SER C 1 382 ? -30.316 11.38   24.619  1    103.55 ? 371 SER C CB  1 -0.278 0.104  0.061  
ATOM   9126  O  OG  . SER C 1 382 ? -30.721 11.018  23.303  1    99.88  ? 371 SER C OG  1 -0.282 0.101  0.058  
ATOM   9127  N  N   . ILE C 1 383 ? -28.492 10.783  26.958  1    106.86 ? 372 ILE C N   1 -0.261 0.099  0.067  
ATOM   9128  C  CA  . ILE C 1 383 ? -28.052 10.722  28.357  1    104.91 ? 372 ILE C CA  1 -0.257 0.098  0.071  
ATOM   9129  C  C   . ILE C 1 383 ? -26.741 11.469  28.545  1    106.58 ? 372 ILE C C   1 -0.245 0.105  0.071  
ATOM   9130  O  O   . ILE C 1 383 ? -26.64  12.399  29.356  1    103.78 ? 372 ILE C O   1 -0.244 0.114  0.073  
ATOM   9131  C  CB  . ILE C 1 383 ? -27.858 9.263   28.826  1    98.4   ? 372 ILE C CB  1 -0.255 0.085  0.072  
ATOM   9132  C  CG1 . ILE C 1 383 ? -29.177 8.481   28.863  1    93.27  ? 372 ILE C CG1 1 -0.267 0.078  0.072  
ATOM   9133  C  CG2 . ILE C 1 383 ? -27.118 9.239   30.138  1    96.74  ? 372 ILE C CG2 1 -0.249 0.085  0.075  
ATOM   9134  C  CD1 . ILE C 1 383 ? -30.15  8.957   29.864  1    100.47 ? 372 ILE C CD1 1 -0.276 0.082  0.075  
ATOM   9135  N  N   . PHE C 1 384 ? -25.729 11.05   27.782  1    104.43 ? 373 PHE C N   1 -0.236 0.101  0.069  
ATOM   9136  C  CA  . PHE C 1 384 ? -24.376 11.538  27.976  1    104.82 ? 373 PHE C CA  1 -0.223 0.106  0.07   
ATOM   9137  C  C   . PHE C 1 384 ? -24.214 12.975  27.51   1    106.18 ? 373 PHE C C   1 -0.222 0.119  0.069  
ATOM   9138  O  O   . PHE C 1 384 ? -23.285 13.662  27.952  1    109.01 ? 373 PHE C O   1 -0.213 0.125  0.07   
ATOM   9139  C  CB  . PHE C 1 384 ? -23.39  10.619  27.246  1    106.38 ? 373 PHE C CB  1 -0.214 0.097  0.068  
ATOM   9140  C  CG  . PHE C 1 384 ? -23.324 9.212   27.806  1    109.91 ? 373 PHE C CG  1 -0.214 0.084  0.069  
ATOM   9141  C  CD1 . PHE C 1 384 ? -23.841 8.916   29.059  1    107.71 ? 373 PHE C CD1 1 -0.218 0.082  0.073  
ATOM   9142  C  CD2 . PHE C 1 384 ? -22.726 8.188   27.081  1    105.92 ? 373 PHE C CD2 1 -0.208 0.075  0.068  
ATOM   9143  C  CE1 . PHE C 1 384 ? -23.776 7.627   29.559  1    108.01 ? 373 PHE C CE1 1 -0.218 0.07   0.074  
ATOM   9144  C  CE2 . PHE C 1 384 ? -22.655 6.899   27.586  1    101.51 ? 373 PHE C CE2 1 -0.208 0.063  0.069  
ATOM   9145  C  CZ  . PHE C 1 384 ? -23.184 6.618   28.817  1    104.31 ? 373 PHE C CZ  1 -0.212 0.061  0.072  
ATOM   9146  N  N   . THR C 1 385 ? -25.09  13.452  26.629  1    105.6  ? 374 THR C N   1 -0.23  0.123  0.066  
ATOM   9147  C  CA  . THR C 1 385 ? -25.045 14.861  26.256  1    107.76 ? 374 THR C CA  1 -0.23  0.136  0.066  
ATOM   9148  C  C   . THR C 1 385 ? -25.523 15.726  27.413  1    108.95 ? 374 THR C C   1 -0.234 0.144  0.068  
ATOM   9149  O  O   . THR C 1 385 ? -24.818 16.648  27.853  1    109.47 ? 374 THR C O   1 -0.227 0.153  0.07   
ATOM   9150  C  CB  . THR C 1 385 ? -25.886 15.107  25      1    107.56 ? 374 THR C CB  1 -0.237 0.138  0.062  
ATOM   9151  O  OG1 . THR C 1 385 ? -25.325 14.371  23.903  1    106.01 ? 374 THR C OG1 1 -0.232 0.132  0.06   
ATOM   9152  C  CG2 . THR C 1 385 ? -25.929 16.603  24.659  1    98.53  ? 374 THR C CG2 1 -0.238 0.152  0.062  
ATOM   9153  N  N   . LEU C 1 386 ? -26.718 15.429  27.93   1    112.38 ? 375 LEU C N   1 -0.245 0.141  0.07   
ATOM   9154  C  CA  . LEU C 1 386 ? -27.204 16.077  29.137  1    104.93 ? 375 LEU C CA  1 -0.249 0.147  0.073  
ATOM   9155  C  C   . LEU C 1 386 ? -26.09  16.049  30.169  1    110.84 ? 375 LEU C C   1 -0.239 0.147  0.075  
ATOM   9156  O  O   . LEU C 1 386 ? -25.813 17.062  30.816  1    120.17 ? 375 LEU C O   1 -0.237 0.156  0.077  
ATOM   9157  C  CB  . LEU C 1 386 ? -28.459 15.386  29.677  1    97.4   ? 375 LEU C CB  1 -0.261 0.141  0.074  
ATOM   9158  C  CG  . LEU C 1 386 ? -29.708 15.433  28.8    1    101.87 ? 375 LEU C CG  1 -0.272 0.141  0.072  
ATOM   9159  C  CD1 . LEU C 1 386 ? -30.977 15.278  29.611  1    111.86 ? 375 LEU C CD1 1 -0.284 0.14   0.074  
ATOM   9160  C  CD2 . LEU C 1 386 ? -29.746 16.734  28.027  1    119.8  ? 375 LEU C CD2 1 -0.273 0.153  0.07   
ATOM   9161  N  N   . TYR C 1 387 ? -25.406 14.91   30.288  1    105.39 ? 376 TYR C N   1 -0.233 0.137  0.076  
ATOM   9162  C  CA  . TYR C 1 387 ? -24.318 14.84   31.256  1    110.46 ? 376 TYR C CA  1 -0.223 0.136  0.078  
ATOM   9163  C  C   . TYR C 1 387 ? -23.179 15.775  30.88   1    113.16 ? 376 TYR C C   1 -0.212 0.145  0.077  
ATOM   9164  O  O   . TYR C 1 387 ? -22.579 16.41   31.759  1    113.86 ? 376 TYR C O   1 -0.207 0.15   0.079  
ATOM   9165  C  CB  . TYR C 1 387 ? -23.792 13.413  31.403  1    106.78 ? 376 TYR C CB  1 -0.218 0.123  0.078  
ATOM   9166  C  CG  . TYR C 1 387 ? -22.54  13.386  32.23   1    105.59 ? 376 TYR C CG  1 -0.207 0.123  0.08   
ATOM   9167  C  CD1 . TYR C 1 387 ? -22.518 13.951  33.497  1    112.32 ? 376 TYR C CD1 1 -0.206 0.128  0.084  
ATOM   9168  C  CD2 . TYR C 1 387 ? -21.374 12.82   31.745  1    109.18 ? 376 TYR C CD2 1 -0.196 0.117  0.079  
ATOM   9169  C  CE1 . TYR C 1 387 ? -21.372 13.938  34.264  1    112.72 ? 376 TYR C CE1 1 -0.196 0.128  0.086  
ATOM   9170  C  CE2 . TYR C 1 387 ? -20.216 12.805  32.505  1    114.22 ? 376 TYR C CE2 1 -0.185 0.117  0.081  
ATOM   9171  C  CZ  . TYR C 1 387 ? -20.221 13.365  33.762  1    117.24 ? 376 TYR C CZ  1 -0.185 0.122  0.084  
ATOM   9172  O  OH  . TYR C 1 387 ? -19.067 13.346  34.516  1    120.01 ? 376 TYR C OH  1 -0.175 0.122  0.086  
ATOM   9173  N  N   . ASN C 1 388 ? -22.87  15.89   29.585  1    107.17 ? 377 ASN C N   1 -0.21  0.146  0.074  
ATOM   9174  C  CA  . ASN C 1 388 ? -21.649 16.598  29.228  1    105.09 ? 377 ASN C CA  1 -0.198 0.152  0.073  
ATOM   9175  C  C   . ASN C 1 388 ? -21.8   18.104  29.402  1    107.6  ? 377 ASN C C   1 -0.2   0.166  0.073  
ATOM   9176  O  O   . ASN C 1 388 ? -20.792 18.806  29.594  1    102.89 ? 377 ASN C O   1 -0.191 0.172  0.074  
ATOM   9177  C  CB  . ASN C 1 388 ? -21.213 16.203  27.825  1    103.77 ? 377 ASN C CB  1 -0.194 0.148  0.069  
ATOM   9178  C  CG  . ASN C 1 388 ? -20.098 15.157  27.86   1    108.61 ? 377 ASN C CG  1 -0.184 0.139  0.07   
ATOM   9179  O  OD1 . ASN C 1 388 ? -19.225 15.233  28.719  1    114.32 ? 377 ASN C OD1 1 -0.176 0.14   0.072  
ATOM   9180  N  ND2 . ASN C 1 388 ? -20.134 14.175  26.959  1    108.16 ? 377 ASN C ND2 1 -0.185 0.13   0.067  
ATOM   9181  N  N   . GLU C 1 389 ? -23.03  18.628  29.343  1    107.02 ? 378 GLU C N   1 -0.211 0.171  0.073  
ATOM   9182  C  CA  . GLU C 1 389 ? -23.279 19.973  29.884  1    118.84 ? 378 GLU C CA  1 -0.213 0.183  0.075  
ATOM   9183  C  C   . GLU C 1 389 ? -23.385 19.963  31.399  1    123.91 ? 378 GLU C C   1 -0.214 0.183  0.078  
ATOM   9184  O  O   . GLU C 1 389 ? -22.541 20.503  32.107  1    127.22 ? 378 GLU C O   1 -0.207 0.188  0.08   
ATOM   9185  C  CB  . GLU C 1 389 ? -24.546 20.574  29.265  1    123.09 ? 378 GLU C CB  1 -0.225 0.189  0.073  
ATOM   9186  C  CG  . GLU C 1 389 ? -24.711 22.063  29.536  1    132.81 ? 378 GLU C CG  1 -0.226 0.202  0.074  
ATOM   9187  C  CD  . GLU C 1 389 ? -25.015 22.397  30.983  1    138.16 ? 378 GLU C CD  1 -0.229 0.205  0.077  
ATOM   9188  O  OE1 . GLU C 1 389 ? -24.343 23.33   31.447  1    139.01 ? 378 GLU C OE1 1 -0.223 0.214  0.079  
ATOM   9189  O  OE2 . GLU C 1 389 ? -25.929 21.803  31.625  1    134.45 ? 378 GLU C OE2 1 -0.238 0.2    0.079  
ATOM   9190  N  N   . ASN C 1 390 ? -24.331 19.242  31.918  1    117.12 ? 379 ASN C N   1 -0.223 0.176  0.08   
ATOM   9191  C  CA  . ASN C 1 390 ? -24.67  19.383  33.336  1    127.74 ? 379 ASN C CA  1 -0.226 0.178  0.083  
ATOM   9192  C  C   . ASN C 1 390 ? -23.654 18.81   34.304  1    128.02 ? 379 ASN C C   1 -0.217 0.172  0.086  
ATOM   9193  O  O   . ASN C 1 390 ? -24.059 18.281  35.355  1    127.79 ? 379 ASN C O   1 -0.22  0.168  0.088  
ATOM   9194  C  CB  . ASN C 1 390 ? -26.021 18.71   33.51   1    129.72 ? 379 ASN C CB  1 -0.238 0.171  0.084  
ATOM   9195  C  CG  . ASN C 1 390 ? -27.11  19.348  32.671  1    122.61 ? 379 ASN C CG  1 -0.248 0.177  0.082  
ATOM   9196  O  OD1 . ASN C 1 390 ? -27.722 18.695  31.834  1    121.46 ? 379 ASN C OD1 1 -0.254 0.171  0.079  
ATOM   9197  N  ND2 . ASN C 1 390 ? -27.386 20.624  32.915  1    120.52 ? 379 ASN C ND2 1 -0.251 0.189  0.082  
ATOM   9198  N  N   . LYS C 1 391 ? -22.334 18.904  34.035  1    121.61 ? 380 LYS C N   1 -0.205 0.173  0.085  
ATOM   9199  C  CA  . LYS C 1 391 ? -21.304 18.569  35.015  1    127.94 ? 380 LYS C CA  1 -0.195 0.17   0.087  
ATOM   9200  C  C   . LYS C 1 391 ? -21.379 19.458  36.252  1    130.94 ? 380 LYS C C   1 -0.196 0.178  0.091  
ATOM   9201  O  O   . LYS C 1 391 ? -20.936 19.047  37.337  1    135.49 ? 380 LYS C O   1 -0.192 0.175  0.093  
ATOM   9202  C  CB  . LYS C 1 391 ? -19.956 18.674  34.319  1    118.81 ? 380 LYS C CB  1 -0.183 0.171  0.086  
ATOM   9203  C  CG  . LYS C 1 391 ? -19.842 17.697  33.178  1    116.32 ? 380 LYS C CG  1 -0.182 0.162  0.083  
ATOM   9204  C  CD  . LYS C 1 391 ? -18.398 17.516  32.791  1    120.89 ? 380 LYS C CD  1 -0.169 0.161  0.082  
ATOM   9205  C  CE  . LYS C 1 391 ? -18.114 16.083  32.385  1    118.54 ? 380 LYS C CE  1 -0.166 0.147  0.081  
ATOM   9206  N  NZ  . LYS C 1 391 ? -17.663 16.009  30.958  1    124.82 ? 380 LYS C NZ  1 -0.162 0.147  0.077  
ATOM   9207  N  N   . ASP C 1 392 ? -21.926 20.669  36.108  1    129.97 ? 381 ASP C N   1 -0.201 0.189  0.09   
ATOM   9208  C  CA  . ASP C 1 392 ? -22.207 21.518  37.259  1    130.24 ? 381 ASP C CA  1 -0.204 0.197  0.093  
ATOM   9209  C  C   . ASP C 1 392 ? -23.296 20.932  38.141  1    130.16 ? 381 ASP C C   1 -0.213 0.192  0.095  
ATOM   9210  O  O   . ASP C 1 392 ? -23.28  21.146  39.356  1    127.25 ? 381 ASP C O   1 -0.213 0.194  0.098  
ATOM   9211  C  CB  . ASP C 1 392 ? -22.628 22.91   36.782  1    135.62 ? 381 ASP C CB  1 -0.207 0.21   0.092  
ATOM   9212  C  CG  . ASP C 1 392 ? -23.774 22.861  35.779  1    139.14 ? 381 ASP C CG  1 -0.218 0.21   0.089  
ATOM   9213  O  OD1 . ASP C 1 392 ? -24.909 22.506  36.196  1    137.94 ? 381 ASP C OD1 1 -0.228 0.206  0.09   
ATOM   9214  O  OD2 . ASP C 1 392 ? -23.539 23.174  34.581  1    134.84 ? 381 ASP C OD2 1 -0.216 0.212  0.086  
ATOM   9215  N  N   . CYS C 1 393 ? -24.261 20.22   37.551  1    132.61 ? 382 CYS C N   1 -0.222 0.185  0.094  
ATOM   9216  C  CA  . CYS C 1 393 ? -25.352 19.615  38.311  1    128.15 ? 382 CYS C CA  1 -0.232 0.18   0.096  
ATOM   9217  C  C   . CYS C 1 393 ? -25.197 18.107  38.48   1    122.72 ? 382 CYS C C   1 -0.231 0.166  0.096  
ATOM   9218  O  O   . CYS C 1 393 ? -25.284 17.604  39.601  1    126.44 ? 382 CYS C O   1 -0.232 0.161  0.099  
ATOM   9219  C  CB  . CYS C 1 393 ? -26.71  19.911  37.658  1    129.16 ? 382 CYS C CB  1 -0.245 0.182  0.094  
ATOM   9220  S  SG  . CYS C 1 393 ? -28.084 19.019  38.482  1    125.47 ? 382 CYS C SG  1 -0.257 0.174  0.096  
ATOM   9221  N  N   . VAL C 1 394 ? -24.989 17.364  37.398  1    123.89 ? 383 VAL C N   1 -0.229 0.159  0.093  
ATOM   9222  C  CA  . VAL C 1 394 ? -24.949 15.911  37.521  1    121.26 ? 383 VAL C CA  1 -0.229 0.146  0.094  
ATOM   9223  C  C   . VAL C 1 394 ? -23.652 15.513  38.226  1    122.32 ? 383 VAL C C   1 -0.217 0.142  0.095  
ATOM   9224  O  O   . VAL C 1 394 ? -22.55  15.757  37.723  1    117.08 ? 383 VAL C O   1 -0.207 0.144  0.094  
ATOM   9225  C  CB  . VAL C 1 394 ? -25.092 15.221  36.165  1    117.33 ? 383 VAL C CB  1 -0.23  0.139  0.09   
ATOM   9226  C  CG1 . VAL C 1 394 ? -24.594 13.782  36.249  1    114.53 ? 383 VAL C CG1 1 -0.225 0.126  0.091  
ATOM   9227  C  CG2 . VAL C 1 394 ? -26.55  15.261  35.728  1    116.8  ? 383 VAL C CG2 1 -0.243 0.14   0.089  
ATOM   9228  N  N   . ASP C 1 395 ? -23.796 14.914  39.413  1    121.4  ? 384 ASP C N   1 -0.218 0.137  0.098  
ATOM   9229  C  CA  . ASP C 1 395 ? -22.647 14.438  40.173  1    120.01 ? 384 ASP C CA  1 -0.208 0.132  0.1    
ATOM   9230  C  C   . ASP C 1 395 ? -22.062 13.175  39.545  1    113.69 ? 384 ASP C C   1 -0.202 0.121  0.099  
ATOM   9231  O  O   . ASP C 1 395 ? -20.889 13.14   39.162  1    102.82 ? 384 ASP C O   1 -0.191 0.12   0.098  
ATOM   9232  C  CB  . ASP C 1 395 ? -23.083 14.173  41.625  1    130.01 ? 384 ASP C CB  1 -0.212 0.13   0.104  
ATOM   9233  C  CG  . ASP C 1 395 ? -22.092 14.726  42.661  1    137.43 ? 384 ASP C CG  1 -0.202 0.135  0.107  
ATOM   9234  O  OD1 . ASP C 1 395 ? -21.154 15.456  42.256  1    135.55 ? 384 ASP C OD1 1 -0.194 0.142  0.106  
ATOM   9235  O  OD2 . ASP C 1 395 ? -22.264 14.427  43.879  1    128.84 ? 384 ASP C OD2 1 -0.204 0.132  0.11   
ATOM   9236  N  N   . THR C 1 396 ? -22.883 12.126  39.44   1    116.72 ? 385 THR C N   1 -0.21  0.111  0.098  
ATOM   9237  C  CA  . THR C 1 396 ? -22.438 10.775  39.132  1    114.64 ? 385 THR C CA  1 -0.206 0.099  0.098  
ATOM   9238  C  C   . THR C 1 396 ? -23.364 10.134  38.105  1    112.44 ? 385 THR C C   1 -0.214 0.093  0.095  
ATOM   9239  O  O   . THR C 1 396 ? -24.576 10.375  38.093  1    113.49 ? 385 THR C O   1 -0.225 0.095  0.095  
ATOM   9240  C  CB  . THR C 1 396 ? -22.416 9.871   40.402  1    123.9  ? 385 THR C CB  1 -0.205 0.09   0.101  
ATOM   9241  O  OG1 . THR C 1 396 ? -23.762 9.539   40.791  1    125.58 ? 385 THR C OG1 1 -0.218 0.087  0.102  
ATOM   9242  C  CG2 . THR C 1 396 ? -21.735 10.562  41.587  1    124.29 ? 385 THR C CG2 1 -0.199 0.097  0.104  
ATOM   9243  N  N   . ILE C 1 397 ? -22.779 9.305   37.245  1    108.31 ? 386 ILE C N   1 -0.209 0.085  0.093  
ATOM   9244  C  CA  . ILE C 1 397 ? -23.518 8.31    36.48   1    110.07 ? 386 ILE C CA  1 -0.216 0.076  0.091  
ATOM   9245  C  C   . ILE C 1 397 ? -22.95  6.955   36.845  1    103.77 ? 386 ILE C C   1 -0.21  0.064  0.092  
ATOM   9246  O  O   . ILE C 1 397 ? -21.725 6.766   36.887  1    99.94  ? 386 ILE C O   1 -0.199 0.062  0.092  
ATOM   9247  C  CB  . ILE C 1 397 ? -23.45  8.539   34.956  1    112.56 ? 386 ILE C CB  1 -0.215 0.078  0.087  
ATOM   9248  C  CG1 . ILE C 1 397 ? -24.29  9.746   34.578  1    111.14 ? 386 ILE C CG1 1 -0.223 0.089  0.086  
ATOM   9249  C  CG2 . ILE C 1 397 ? -23.988 7.334   34.189  1    104.09 ? 386 ILE C CG2 1 -0.22  0.067  0.085  
ATOM   9250  C  CD1 . ILE C 1 397 ? -23.489 10.818  33.967  1    111.99 ? 386 ILE C CD1 1 -0.215 0.099  0.085  
ATOM   9251  N  N   . TYR C 1 398 ? -23.839 6.03    37.132  1    94.79  ? 387 TYR C N   1 -0.218 0.055  0.093  
ATOM   9252  C  CA  . TYR C 1 398 ? -23.429 4.677   37.412  1    93.6   ? 387 TYR C CA  1 -0.215 0.043  0.093  
ATOM   9253  C  C   . TYR C 1 398 ? -24.326 3.728   36.646  1    100.44 ? 387 TYR C C   1 -0.223 0.034  0.091  
ATOM   9254  O  O   . TYR C 1 398 ? -25.556 3.848   36.693  1    100.53 ? 387 TYR C O   1 -0.234 0.035  0.092  
ATOM   9255  C  CB  . TYR C 1 398 ? -23.503 4.356   38.869  1    104.92 ? 387 TYR C CB  1 -0.215 0.04   0.097  
ATOM   9256  C  CG  . TYR C 1 398 ? -23.557 2.862   39.063  1    98.97  ? 387 TYR C CG  1 -0.216 0.026  0.098  
ATOM   9257  C  CD1 . TYR C 1 398 ? -22.403 2.07    39.08   1    94.78  ? 387 TYR C CD1 1 -0.205 0.019  0.098  
ATOM   9258  C  CD2 . TYR C 1 398 ? -24.772 2.243   39.196  1    97.05  ? 387 TYR C CD2 1 -0.227 0.021  0.098  
ATOM   9259  C  CE1 . TYR C 1 398 ? -22.484 0.661   39.249  1    88.83  ? 387 TYR C CE1 1 -0.206 0.006  0.098  
ATOM   9260  C  CE2 . TYR C 1 398 ? -24.88  0.884   39.346  1    97.57  ? 387 TYR C CE2 1 -0.228 0.008  0.098  
ATOM   9261  C  CZ  . TYR C 1 398 ? -23.722 0.065   39.385  1    95.04  ? 387 TYR C CZ  1 -0.217 0.001  0.098  
ATOM   9262  O  OH  . TYR C 1 398 ? -23.73  -1.319  39.552  1    91.59  ? 387 TYR C OH  1 -0.217 -0.012 0.099  
ATOM   9263  N  N   . TRP C 1 399 ? -23.696 2.737   36.019  1    102.05 ? 388 TRP C N   1 -0.217 0.025  0.09   
ATOM   9264  C  CA  . TRP C 1 399 ? -24.352 1.832   35.078  1    102.92 ? 388 TRP C CA  1 -0.223 0.017  0.088  
ATOM   9265  C  C   . TRP C 1 399 ? -24.118 0.392   35.524  1    100.87 ? 388 TRP C C   1 -0.221 0.004  0.089  
ATOM   9266  O  O   . TRP C 1 399 ? -22.968 -0.026  35.734  1    95.18  ? 388 TRP C O   1 -0.21  -0.0   0.089  
ATOM   9267  C  CB  . TRP C 1 399 ? -23.807 2.082   33.663  1    100.05 ? 388 TRP C CB  1 -0.218 0.019  0.084  
ATOM   9268  C  CG  . TRP C 1 399 ? -24.474 1.361   32.492  1    102.77 ? 388 TRP C CG  1 -0.224 0.012  0.081  
ATOM   9269  C  CD1 . TRP C 1 399 ? -25.42  1.871   31.625  1    106.06 ? 388 TRP C CD1 1 -0.233 0.017  0.079  
ATOM   9270  C  CD2 . TRP C 1 399 ? -24.182 0.038   32.02   1    101.86 ? 388 TRP C CD2 1 -0.222 0.0    0.08   
ATOM   9271  N  NE1 . TRP C 1 399 ? -25.748 0.932   30.664  1    104.55 ? 388 TRP C NE1 1 -0.236 0.009  0.077  
ATOM   9272  C  CE2 . TRP C 1 399 ? -25.004 -0.199  30.883  1    105.53 ? 388 TRP C CE2 1 -0.229 -0.002 0.077  
ATOM   9273  C  CE3 . TRP C 1 399 ? -23.314 -0.969  32.446  1    94.95  ? 388 TRP C CE3 1 -0.214 -0.009 0.081  
ATOM   9274  C  CZ2 . TRP C 1 399 ? -24.982 -1.407  30.184  1    97.04  ? 388 TRP C CZ2 1 -0.229 -0.013 0.075  
ATOM   9275  C  CZ3 . TRP C 1 399 ? -23.295 -2.168  31.743  1    97.62  ? 388 TRP C CZ3 1 -0.213 -0.02  0.079  
ATOM   9276  C  CH2 . TRP C 1 399 ? -24.124 -2.374  30.625  1    93.99  ? 388 TRP C CH2 1 -0.221 -0.022 0.076  
ATOM   9277  N  N   . GLY C 1 400 ? -25.205 -0.366  35.665  1    95.69  ? 389 GLY C N   1 -0.231 -0.003 0.089  
ATOM   9278  C  CA  . GLY C 1 400 ? -25.076 -1.728  36.126  1    94.58  ? 389 GLY C CA  1 -0.23  -0.016 0.09   
ATOM   9279  C  C   . GLY C 1 400 ? -25.656 -2.756  35.189  1    91.41  ? 389 GLY C C   1 -0.235 -0.025 0.088  
ATOM   9280  O  O   . GLY C 1 400 ? -26.853 -2.741  34.886  1    91.2   ? 389 GLY C O   1 -0.246 -0.025 0.087  
ATOM   9281  N  N   . LEU C 1 401 ? -24.794 -3.654  34.725  1    92.01  ? 390 LEU C N   1 -0.227 -0.033 0.087  
ATOM   9282  C  CA  . LEU C 1 401 ? -25.203 -4.784  33.903  1    96.83  ? 390 LEU C CA  1 -0.231 -0.044 0.085  
ATOM   9283  C  C   . LEU C 1 401 ? -26.232 -5.612  34.66   1    99.55  ? 390 LEU C C   1 -0.24  -0.051 0.087  
ATOM   9284  O  O   . LEU C 1 401 ? -25.895 -6.357  35.588  1    100.13 ? 390 LEU C O   1 -0.237 -0.058 0.089  
ATOM   9285  C  CB  . LEU C 1 401 ? -23.978 -5.627  33.515  1    97.8   ? 390 LEU C CB  1 -0.22  -0.052 0.084  
ATOM   9286  C  CG  . LEU C 1 401 ? -24.069 -6.872  32.626  1    97.26  ? 390 LEU C CG  1 -0.221 -0.063 0.081  
ATOM   9287  C  CD1 . LEU C 1 401 ? -24.475 -8.121  33.423  1    106.95 ? 390 LEU C CD1 1 -0.224 -0.074 0.083  
ATOM   9288  C  CD2 . LEU C 1 401 ? -25.006 -6.638  31.442  1    96.85  ? 390 LEU C CD2 1 -0.229 -0.061 0.079  
ATOM   9289  N  N   . GLU C 1 402 ? -27.489 -5.476  34.271  1    102.21 ? 391 GLU C N   1 -0.252 -0.05  0.086  
ATOM   9290  C  CA  . GLU C 1 402 ? -28.582 -6.224  34.873  1    101.38 ? 391 GLU C CA  1 -0.262 -0.057 0.087  
ATOM   9291  C  C   . GLU C 1 402 ? -28.819 -7.518  34.086  1    106.89 ? 391 GLU C C   1 -0.264 -0.069 0.085  
ATOM   9292  O  O   . GLU C 1 402 ? -28.129 -8.524  34.315  1    107.94 ? 391 GLU C O   1 -0.258 -0.078 0.086  
ATOM   9293  C  CB  . GLU C 1 402 ? -29.822 -5.329  34.907  1    101.8  ? 391 GLU C CB  1 -0.273 -0.049 0.087  
ATOM   9294  C  CG  . GLU C 1 402 ? -30.574 -5.226  36.225  1    108.52 ? 391 GLU C CG  1 -0.28  -0.048 0.09   
ATOM   9295  C  CD  . GLU C 1 402 ? -29.706 -4.989  37.478  1    113.78 ? 391 GLU C CD  1 -0.272 -0.046 0.094  
ATOM   9296  O  OE1 . GLU C 1 402 ? -29.973 -5.659  38.509  1    108.82 ? 391 GLU C OE1 1 -0.275 -0.052 0.096  
ATOM   9297  O  OE2 . GLU C 1 402 ? -28.792 -4.123  37.456  1    117.12 ? 391 GLU C OE2 1 -0.264 -0.038 0.094  
ATOM   9298  N  N   . GLY C 1 403 ? -29.772 -7.499  33.146  1    104.24 ? 392 GLY C N   1 -0.273 -0.069 0.083  
ATOM   9299  C  CA  . GLY C 1 403 ? -30.067 -8.652  32.312  1    107.94 ? 392 GLY C CA  1 -0.276 -0.079 0.081  
ATOM   9300  C  C   . GLY C 1 403 ? -29.79  -8.468  30.826  1    110.41 ? 392 GLY C C   1 -0.273 -0.078 0.077  
ATOM   9301  O  O   . GLY C 1 403 ? -29.106 -7.512  30.425  1    108.57 ? 392 GLY C O   1 -0.267 -0.069 0.076  
ATOM   9302  N  N   . GLY C 1 404 ? -30.319 -9.36   29.993  1    110.08 ? 393 GLY C N   1 -0.278 -0.086 0.075  
ATOM   9303  C  CA  . GLY C 1 404 ? -30.042 -9.341  28.562  1    108.49 ? 393 GLY C CA  1 -0.275 -0.086 0.071  
ATOM   9304  C  C   . GLY C 1 404 ? -29.156 -10.502 28.156  1    108.77 ? 393 GLY C C   1 -0.267 -0.096 0.07   
ATOM   9305  O  O   . GLY C 1 404 ? -27.965 -10.502 28.48   1    109.15 ? 393 GLY C O   1 -0.256 -0.096 0.071  
ATOM   9306  N  N   . TYR C 1 405 ? -29.7   -11.491 27.446  1    106.76 ? 394 TYR C N   1 -0.272 -0.105 0.069  
ATOM   9307  C  CA  . TYR C 1 405 ? -29.002 -12.767 27.575  1    107.39 ? 394 TYR C CA  1 -0.266 -0.117 0.069  
ATOM   9308  C  C   . TYR C 1 405 ? -28.573 -13.402 26.261  1    107.89 ? 394 TYR C C   1 -0.262 -0.123 0.066  
ATOM   9309  O  O   . TYR C 1 405 ? -27.486 -13.99  26.217  1    106.13 ? 394 TYR C O   1 -0.252 -0.128 0.065  
ATOM   9310  C  CB  . TYR C 1 405 ? -29.887 -13.729 28.408  1    110.02 ? 394 TYR C CB  1 -0.274 -0.126 0.071  
ATOM   9311  C  CG  . TYR C 1 405 ? -30.218 -13.154 29.778  1    107.13 ? 394 TYR C CG  1 -0.277 -0.121 0.074  
ATOM   9312  C  CD1 . TYR C 1 405 ? -29.238 -13.069 30.766  1    110.3  ? 394 TYR C CD1 1 -0.268 -0.12  0.077  
ATOM   9313  C  CD2 . TYR C 1 405 ? -31.49  -12.661 30.066  1    104.44 ? 394 TYR C CD2 1 -0.289 -0.116 0.075  
ATOM   9314  C  CE1 . TYR C 1 405 ? -29.513 -12.53  32.025  1    111.51 ? 394 TYR C CE1 1 -0.27  -0.115 0.08   
ATOM   9315  C  CE2 . TYR C 1 405 ? -31.788 -12.124 31.319  1    115.02 ? 394 TYR C CE2 1 -0.291 -0.111 0.078  
ATOM   9316  C  CZ  . TYR C 1 405 ? -30.792 -12.062 32.306  1    117.91 ? 394 TYR C CZ  1 -0.282 -0.111 0.081  
ATOM   9317  O  OH  . TYR C 1 405 ? -31.061 -11.524 33.566  1    110.66 ? 394 TYR C OH  1 -0.285 -0.106 0.084  
ATOM   9318  N  N   . ASP C 1 406 ? -29.375 -13.301 25.195  1    105.65 ? 395 ASP C N   1 -0.269 -0.122 0.063  
ATOM   9319  C  CA  . ASP C 1 406 ? -28.947 -13.819 23.891  1    105.42 ? 395 ASP C CA  1 -0.265 -0.127 0.06   
ATOM   9320  C  C   . ASP C 1 406 ? -27.627 -13.186 23.463  1    100.54 ? 395 ASP C C   1 -0.253 -0.121 0.059  
ATOM   9321  O  O   . ASP C 1 406 ? -27.465 -11.966 23.533  1    103.93 ? 395 ASP C O   1 -0.252 -0.11  0.059  
ATOM   9322  C  CB  . ASP C 1 406 ? -30.005 -13.544 22.824  1    110.24 ? 395 ASP C CB  1 -0.275 -0.124 0.057  
ATOM   9323  C  CG  . ASP C 1 406 ? -29.637 -14.158 21.492  1    108.03 ? 395 ASP C CG  1 -0.272 -0.13  0.054  
ATOM   9324  O  OD1 . ASP C 1 406 ? -29.734 -15.402 21.396  1    105.99 ? 395 ASP C OD1 1 -0.272 -0.141 0.053  
ATOM   9325  O  OD2 . ASP C 1 406 ? -29.23  -13.417 20.56   1    108.24 ? 395 ASP C OD2 1 -0.268 -0.123 0.051  
ATOM   9326  N  N   . ARG C 1 407 ? -26.691 -14.006 22.984  1    93.56  ? 396 ARG C N   1 -0.245 -0.128 0.057  
ATOM   9327  C  CA  . ARG C 1 407 ? -25.313 -13.531 22.885  1    93.98  ? 396 ARG C CA  1 -0.232 -0.124 0.057  
ATOM   9328  C  C   . ARG C 1 407 ? -25.111 -12.527 21.753  1    101.07 ? 396 ARG C C   1 -0.23  -0.115 0.054  
ATOM   9329  O  O   . ARG C 1 407 ? -24.695 -11.387 21.993  1    102.56 ? 396 ARG C O   1 -0.226 -0.104 0.055  
ATOM   9330  C  CB  . ARG C 1 407 ? -24.34  -14.686 22.722  1    91.57  ? 396 ARG C CB  1 -0.223 -0.135 0.057  
ATOM   9331  C  CG  . ARG C 1 407 ? -22.973 -14.169 22.32   1    86.74  ? 396 ARG C CG  1 -0.211 -0.13  0.056  
ATOM   9332  C  CD  . ARG C 1 407 ? -21.935 -15.221 22.496  1    92.67  ? 396 ARG C CD  1 -0.201 -0.139 0.056  
ATOM   9333  N  NE  . ARG C 1 407 ? -20.621 -14.725 22.13   1    90.84  ? 396 ARG C NE  1 -0.189 -0.135 0.055  
ATOM   9334  C  CZ  . ARG C 1 407 ? -19.502 -15.429 22.24   1    98.65  ? 396 ARG C CZ  1 -0.179 -0.141 0.056  
ATOM   9335  N  NH1 . ARG C 1 407 ? -19.501 -16.662 22.729  1    92.07  ? 396 ARG C NH1 1 -0.179 -0.153 0.057  
ATOM   9336  N  NH2 . ARG C 1 407 ? -18.356 -14.89  21.834  1    103.96 ? 396 ARG C NH2 1 -0.168 -0.136 0.055  
ATOM   9337  N  N   . THR C 1 408 ? -25.349 -12.934 20.501  1    106.86 ? 397 THR C N   1 -0.232 -0.119 0.051  
ATOM   9338  C  CA  . THR C 1 408 ? -25.053 -12.023 19.394  1    104.4  ? 397 THR C CA  1 -0.23  -0.11  0.048  
ATOM   9339  C  C   . THR C 1 408 ? -25.839 -10.722 19.488  1    101.58 ? 397 THR C C   1 -0.237 -0.098 0.049  
ATOM   9340  O  O   . THR C 1 408 ? -25.5   -9.762  18.781  1    98.6   ? 397 THR C O   1 -0.234 -0.089 0.047  
ATOM   9341  C  CB  . THR C 1 408 ? -25.327 -12.7   18.056  1    103.6  ? 397 THR C CB  1 -0.232 -0.116 0.045  
ATOM   9342  O  OG1 . THR C 1 408 ? -26.637 -13.278 18.095  1    109.96 ? 397 THR C OG1 1 -0.244 -0.122 0.045  
ATOM   9343  C  CG2 . THR C 1 408 ? -24.273 -13.787 17.781  1    101.1  ? 397 THR C CG2 1 -0.222 -0.126 0.044  
ATOM   9344  N  N   . MET C 1 409 ? -26.862 -10.676 20.352  1    99.77  ? 398 MET C N   1 -0.246 -0.098 0.051  
ATOM   9345  C  CA  . MET C 1 409 ? -27.563 -9.45   20.716  1    98.8   ? 398 MET C CA  1 -0.253 -0.087 0.052  
ATOM   9346  C  C   . MET C 1 409 ? -26.739 -8.59   21.671  1    102.16 ? 398 MET C C   1 -0.245 -0.079 0.054  
ATOM   9347  O  O   . MET C 1 409 ? -26.555 -7.388  21.446  1    99.05  ? 398 MET C O   1 -0.243 -0.068 0.054  
ATOM   9348  C  CB  . MET C 1 409 ? -28.905 -9.801  21.362  1    100.28 ? 398 MET C CB  1 -0.265 -0.09  0.053  
ATOM   9349  C  CG  . MET C 1 409 ? -29.88  -8.646  21.509  1    103.65 ? 398 MET C CG  1 -0.274 -0.079 0.054  
ATOM   9350  S  SD  . MET C 1 409 ? -29.548 -7.633  22.943  1    106.87 ? 398 MET C SD  1 -0.271 -0.07  0.057  
ATOM   9351  C  CE  . MET C 1 409 ? -29.29  -8.885  24.217  1    105.61 ? 398 MET C CE  1 -0.268 -0.081 0.06   
ATOM   9352  N  N   . TYR C 1 410 ? -26.264 -9.18   22.77   1    108.73 ? 399 TYR C N   1 -0.241 -0.084 0.057  
ATOM   9353  C  CA  . TYR C 1 410 ? -25.591 -8.37   23.776  1    105.28 ? 399 TYR C CA  1 -0.235 -0.077 0.059  
ATOM   9354  C  C   . TYR C 1 410 ? -24.162 -8.018  23.365  1    103.45 ? 399 TYR C C   1 -0.221 -0.073 0.058  
ATOM   9355  O  O   . TYR C 1 410 ? -23.72  -6.885  23.618  1    98.78  ? 399 TYR C O   1 -0.217 -0.063 0.059  
ATOM   9356  C  CB  . TYR C 1 410 ? -25.66  -9.055  25.151  1    98.69  ? 399 TYR C CB  1 -0.235 -0.083 0.063  
ATOM   9357  C  CG  . TYR C 1 410 ? -24.865 -10.34  25.373  1    99.4   ? 399 TYR C CG  1 -0.228 -0.095 0.063  
ATOM   9358  C  CD1 . TYR C 1 410 ? -23.474 -10.37  25.257  1    95.17  ? 399 TYR C CD1 1 -0.215 -0.095 0.063  
ATOM   9359  C  CD2 . TYR C 1 410 ? -25.5   -11.498 25.817  1    103.38 ? 399 TYR C CD2 1 -0.234 -0.105 0.064  
ATOM   9360  C  CE1 . TYR C 1 410 ? -22.748 -11.533 25.505  1    95.22  ? 399 TYR C CE1 1 -0.208 -0.106 0.064  
ATOM   9361  C  CE2 . TYR C 1 410 ? -24.776 -12.672 26.083  1    98.07  ? 399 TYR C CE2 1 -0.227 -0.116 0.065  
ATOM   9362  C  CZ  . TYR C 1 410 ? -23.399 -12.676 25.916  1    96.36  ? 399 TYR C CZ  1 -0.214 -0.116 0.065  
ATOM   9363  O  OH  . TYR C 1 410 ? -22.654 -13.811 26.148  1    94.21  ? 399 TYR C OH  1 -0.208 -0.127 0.065  
ATOM   9364  N  N   . GLU C 1 411 ? -23.438 -8.935  22.704  1    104.67 ? 400 GLU C N   1 -0.215 -0.082 0.057  
ATOM   9365  C  CA  . GLU C 1 411 ? -22.13  -8.583  22.146  1    101.8  ? 400 GLU C CA  1 -0.203 -0.079 0.055  
ATOM   9366  C  C   . GLU C 1 411 ? -22.243 -7.371  21.243  1    97.45  ? 400 GLU C C   1 -0.204 -0.068 0.053  
ATOM   9367  O  O   . GLU C 1 411 ? -21.426 -6.449  21.311  1    97.46  ? 400 GLU C O   1 -0.196 -0.059 0.053  
ATOM   9368  C  CB  . GLU C 1 411 ? -21.538 -9.767  21.392  1    94.58  ? 400 GLU C CB  1 -0.197 -0.09  0.053  
ATOM   9369  C  CG  . GLU C 1 411 ? -21.177 -10.953 22.247  1    96.96  ? 400 GLU C CG  1 -0.194 -0.1   0.056  
ATOM   9370  C  CD  . GLU C 1 411 ? -19.857 -11.53  21.842  1    103.28 ? 400 GLU C CD  1 -0.182 -0.106 0.055  
ATOM   9371  O  OE1 . GLU C 1 411 ? -19.415 -11.246 20.707  1    116.24 ? 400 GLU C OE1 1 -0.178 -0.103 0.052  
ATOM   9372  O  OE2 . GLU C 1 411 ? -19.243 -12.246 22.651  1    98.92  ? 400 GLU C OE2 1 -0.176 -0.112 0.057  
ATOM   9373  N  N   . ARG C 1 412 ? -23.285 -7.343  20.408  1    102.86 ? 401 ARG C N   1 -0.213 -0.067 0.051  
ATOM   9374  C  CA  . ARG C 1 412 ? -23.594 -6.172  19.556  1    104.89 ? 401 ARG C CA  1 -0.216 -0.057 0.049  
ATOM   9375  C  C   . ARG C 1 412 ? -23.84  -4.899  20.368  1    102.38 ? 401 ARG C C   1 -0.218 -0.045 0.051  
ATOM   9376  O  O   . ARG C 1 412 ? -23.17  -3.859  20.172  1    99.12  ? 401 ARG C O   1 -0.212 -0.035 0.05   
ATOM   9377  C  CB  . ARG C 1 412 ? -24.829 -6.452  18.682  1    101.34 ? 401 ARG C CB  1 -0.228 -0.059 0.047  
ATOM   9378  C  CG  . ARG C 1 412 ? -25.142 -5.313  17.746  1    107.89 ? 401 ARG C CG  1 -0.23  -0.049 0.044  
ATOM   9379  C  CD  . ARG C 1 412 ? -25.918 -5.73   16.479  1    103.46 ? 401 ARG C CD  1 -0.238 -0.053 0.041  
ATOM   9380  N  NE  . ARG C 1 412 ? -26.888 -6.796  16.706  1    103.94 ? 401 ARG C NE  1 -0.246 -0.062 0.042  
ATOM   9381  C  CZ  . ARG C 1 412 ? -28.184 -6.609  16.927  1    99.92  ? 401 ARG C CZ  1 -0.258 -0.061 0.042  
ATOM   9382  N  NH1 . ARG C 1 412 ? -28.715 -5.394  16.95   1    95.81  ? 401 ARG C NH1 1 -0.263 -0.049 0.042  
ATOM   9383  N  NH2 . ARG C 1 412 ? -28.965 -7.672  17.131  1    89.8   ? 401 ARG C NH2 1 -0.265 -0.07  0.043  
ATOM   9384  N  N   . GLU C 1 413 ? -24.898 -4.924  21.181  1    104.58 ? 402 GLU C N   1 -0.228 -0.045 0.053  
ATOM   9385  C  CA  . GLU C 1 413 ? -25.239 -3.796  22.065  1    103.13 ? 402 GLU C CA  1 -0.231 -0.035 0.055  
ATOM   9386  C  C   . GLU C 1 413 ? -24.035 -3.263  22.828  1    99.15  ? 402 GLU C C   1 -0.22  -0.03  0.057  
ATOM   9387  O  O   . GLU C 1 413 ? -23.866 -2.039  22.973  1    95.61  ? 402 GLU C O   1 -0.219 -0.019 0.057  
ATOM   9388  C  CB  . GLU C 1 413 ? -26.294 -4.206  23.085  1    101.02 ? 402 GLU C CB  1 -0.241 -0.039 0.058  
ATOM   9389  C  CG  . GLU C 1 413 ? -27.651 -4.634  22.552  1    106.95 ? 402 GLU C CG  1 -0.253 -0.042 0.056  
ATOM   9390  C  CD  . GLU C 1 413 ? -27.992 -4.049  21.22   1    108.57 ? 402 GLU C CD  1 -0.257 -0.037 0.053  
ATOM   9391  O  OE1 . GLU C 1 413 ? -28.373 -4.844  20.329  1    106.64 ? 402 GLU C OE1 1 -0.26  -0.044 0.051  
ATOM   9392  O  OE2 . GLU C 1 413 ? -27.911 -2.801  21.095  1    111.7  ? 402 GLU C OE2 1 -0.256 -0.026 0.053  
ATOM   9393  N  N   . LEU C 1 414 ? -23.253 -4.171  23.425  1    93.86  ? 403 LEU C N   1 -0.213 -0.038 0.058  
ATOM   9394  C  CA  . LEU C 1 414 ? -22.043 -3.744  24.118  1    98.07  ? 403 LEU C CA  1 -0.202 -0.034 0.06   
ATOM   9395  C  C   . LEU C 1 414 ? -21.201 -2.831  23.225  1    100.93 ? 403 LEU C C   1 -0.194 -0.026 0.058  
ATOM   9396  O  O   . LEU C 1 414 ? -20.736 -1.768  23.662  1    99.72  ? 403 LEU C O   1 -0.19  -0.016 0.059  
ATOM   9397  C  CB  . LEU C 1 414 ? -21.232 -4.947  24.548  1    96.33  ? 403 LEU C CB  1 -0.195 -0.045 0.061  
ATOM   9398  C  CG  . LEU C 1 414 ? -20.171 -4.498  25.546  1    93.07  ? 403 LEU C CG  1 -0.185 -0.041 0.064  
ATOM   9399  C  CD1 . LEU C 1 414 ? -20.93  -3.97   26.738  1    97.55  ? 403 LEU C CD1 1 -0.192 -0.036 0.067  
ATOM   9400  C  CD2 . LEU C 1 414 ? -19.233 -5.638  25.92   1    88.75  ? 403 LEU C CD2 1 -0.176 -0.052 0.065  
ATOM   9401  N  N   . LYS C 1 415 ? -21.004 -3.236  21.957  1    99.05  ? 404 LYS C N   1 -0.192 -0.03  0.055  
ATOM   9402  C  CA  . LYS C 1 415 ? -20.224 -2.409  21.044  1    99.64  ? 404 LYS C CA  1 -0.185 -0.022 0.053  
ATOM   9403  C  C   . LYS C 1 415 ? -20.904 -1.068  20.765  1    97.31  ? 404 LYS C C   1 -0.192 -0.01  0.052  
ATOM   9404  O  O   . LYS C 1 415 ? -20.23  -0.031  20.733  1    98.26  ? 404 LYS C O   1 -0.185 -0.0   0.052  
ATOM   9405  C  CB  . LYS C 1 415 ? -19.94  -3.148  19.739  1    97.04  ? 404 LYS C CB  1 -0.183 -0.029 0.049  
ATOM   9406  C  CG  . LYS C 1 415 ? -18.481 -3.028  19.31   1    102.36 ? 404 LYS C CG  1 -0.169 -0.028 0.048  
ATOM   9407  C  CD  . LYS C 1 415 ? -18.291 -3.213  17.795  1    110.87 ? 404 LYS C CD  1 -0.168 -0.029 0.044  
ATOM   9408  C  CE  . LYS C 1 415 ? -16.821 -3.515  17.501  1    118.83 ? 404 LYS C CE  1 -0.154 -0.032 0.044  
ATOM   9409  N  NZ  . LYS C 1 415 ? -16.365 -3.33   16.095  1    107.51 ? 404 LYS C NZ  1 -0.15  -0.031 0.04   
ATOM   9410  N  N   . ILE C 1 416 ? -22.218 -1.04   20.559  1    95.15  ? 405 ILE C N   1 -0.204 -0.01  0.051  
ATOM   9411  C  CA  . ILE C 1 416 ? -22.851 0.258   20.331  1    97.34  ? 405 ILE C CA  1 -0.209 0.002  0.051  
ATOM   9412  C  C   . ILE C 1 416 ? -22.641 1.178   21.543  1    98.83  ? 405 ILE C C   1 -0.207 0.011  0.054  
ATOM   9413  O  O   . ILE C 1 416 ? -22.473 2.401   21.395  1    98.48  ? 405 ILE C O   1 -0.206 0.022  0.053  
ATOM   9414  C  CB  . ILE C 1 416 ? -24.346 0.079   19.975  1    95.3   ? 405 ILE C CB  1 -0.223 0.001  0.05   
ATOM   9415  C  CG1 . ILE C 1 416 ? -24.566 -0.738  18.653  1    97.64  ? 405 ILE C CG1 1 -0.225 -0.007 0.047  
ATOM   9416  C  CG2 . ILE C 1 416 ? -25.05  1.471   20.05   1    98.86  ? 405 ILE C CG2 1 -0.23  0.013  0.05   
ATOM   9417  C  CD1 . ILE C 1 416 ? -25.658 -1.96   18.634  1    100.65 ? 405 ILE C CD1 1 -0.235 -0.018 0.047  
ATOM   9418  N  N   . LEU C 1 417 ? -22.669 0.61    22.761  1    101.8  ? 406 LEU C N   1 -0.208 0.006  0.057  
ATOM   9419  C  CA  . LEU C 1 417 ? -22.511 1.414   23.983  1    98.89  ? 406 LEU C CA  1 -0.206 0.013  0.06   
ATOM   9420  C  C   . LEU C 1 417 ? -21.056 1.845   24.175  1    97.13  ? 406 LEU C C   1 -0.193 0.017  0.06   
ATOM   9421  O  O   . LEU C 1 417 ? -20.781 3.032   24.397  1    98.43  ? 406 LEU C O   1 -0.19  0.028  0.061  
ATOM   9422  C  CB  . LEU C 1 417 ? -23.046 0.648   25.212  1    97.72  ? 406 LEU C CB  1 -0.211 0.006  0.063  
ATOM   9423  C  CG  . LEU C 1 417 ? -22.899 1.159   26.654  1    97.05  ? 406 LEU C CG  1 -0.21  0.011  0.067  
ATOM   9424  C  CD1 . LEU C 1 417 ? -21.456 0.902   27.229  1    97.66  ? 406 LEU C CD1 1 -0.197 0.008  0.068  
ATOM   9425  C  CD2 . LEU C 1 417 ? -23.402 2.631   26.762  1    94.13  ? 406 LEU C CD2 1 -0.214 0.024  0.067  
ATOM   9426  N  N   . LEU C 1 418 ? -20.103 0.909   24.036  1    95.09  ? 407 LEU C N   1 -0.184 0.008  0.06   
ATOM   9427  C  CA  . LEU C 1 418 ? -18.687 1.278   24.129  1    97.96  ? 407 LEU C CA  1 -0.171 0.012  0.06   
ATOM   9428  C  C   . LEU C 1 418 ? -18.314 2.355   23.115  1    100.7  ? 407 LEU C C   1 -0.168 0.022  0.058  
ATOM   9429  O  O   . LEU C 1 418 ? -17.435 3.189   23.385  1    94.82  ? 407 LEU C O   1 -0.16  0.029  0.058  
ATOM   9430  C  CB  . LEU C 1 418 ? -17.786 0.063   23.919  1    93.78  ? 407 LEU C CB  1 -0.163 0.001  0.06   
ATOM   9431  C  CG  . LEU C 1 418 ? -17.995 -1.1    24.867  1    95.92  ? 407 LEU C CG  1 -0.165 -0.01  0.062  
ATOM   9432  C  CD1 . LEU C 1 418 ? -16.877 -2.094  24.745  1    94.24  ? 407 LEU C CD1 1 -0.155 -0.019 0.062  
ATOM   9433  C  CD2 . LEU C 1 418 ? -18.077 -0.543  26.262  1    100.14 ? 407 LEU C CD2 1 -0.166 -0.005 0.066  
ATOM   9434  N  N   . GLN C 1 419 ? -18.948 2.328   21.936  1    105.06 ? 408 GLN C N   1 -0.174 0.021  0.055  
ATOM   9435  C  CA  . GLN C 1 419 ? -18.733 3.372   20.944  1    100.86 ? 408 GLN C CA  1 -0.172 0.031  0.052  
ATOM   9436  C  C   . GLN C 1 419 ? -19.267 4.708   21.447  1    101.77 ? 408 GLN C C   1 -0.177 0.043  0.054  
ATOM   9437  O  O   . GLN C 1 419 ? -18.554 5.717   21.419  1    104.85 ? 408 GLN C O   1 -0.17  0.052  0.053  
ATOM   9438  C  CB  . GLN C 1 419 ? -19.371 2.966   19.61   1    104.46 ? 408 GLN C CB  1 -0.178 0.027  0.049  
ATOM   9439  C  CG  . GLN C 1 419 ? -18.455 2.031   18.804  1    107.15 ? 408 GLN C CG  1 -0.169 0.019  0.047  
ATOM   9440  C  CD  . GLN C 1 419 ? -19.079 1.425   17.553  1    107.57 ? 408 GLN C CD  1 -0.175 0.013  0.044  
ATOM   9441  O  OE1 . GLN C 1 419 ? -20.22  1.736   17.179  1    106.93 ? 408 GLN C OE1 1 -0.185 0.016  0.043  
ATOM   9442  N  NE2 . GLN C 1 419 ? -18.316 0.543   16.896  1    106.45 ? 408 GLN C NE2 1 -0.168 0.005  0.042  
ATOM   9443  N  N   . VAL C 1 420 ? -20.502 4.726   21.961  1    99.52  ? 409 VAL C N   1 -0.188 0.043  0.055  
ATOM   9444  C  CA  . VAL C 1 420 ? -21.035 5.961   22.537  1    100.52 ? 409 VAL C CA  1 -0.193 0.055  0.056  
ATOM   9445  C  C   . VAL C 1 420 ? -20.13  6.472   23.652  1    103.38 ? 409 VAL C C   1 -0.184 0.059  0.059  
ATOM   9446  O  O   . VAL C 1 420 ? -19.996 7.689   23.845  1    102.91 ? 409 VAL C O   1 -0.183 0.07   0.06   
ATOM   9447  C  CB  . VAL C 1 420 ? -22.479 5.763   23.049  1    102.49 ? 409 VAL C CB  1 -0.206 0.053  0.058  
ATOM   9448  C  CG1 . VAL C 1 420 ? -23.029 7.076   23.654  1    104.1  ? 409 VAL C CG1 1 -0.211 0.065  0.059  
ATOM   9449  C  CG2 . VAL C 1 420 ? -23.387 5.26    21.94   1    95.4   ? 409 VAL C CG2 1 -0.214 0.048  0.055  
ATOM   9450  N  N   . ILE C 1 421 ? -19.49  5.571   24.397  1    99.12  ? 410 ILE C N   1 -0.179 0.051  0.061  
ATOM   9451  C  CA  . ILE C 1 421 ? -18.637 6.016   25.495  1    107.33 ? 410 ILE C CA  1 -0.171 0.055  0.064  
ATOM   9452  C  C   . ILE C 1 421 ? -17.387 6.694   24.944  1    106.36 ? 410 ILE C C   1 -0.159 0.061  0.062  
ATOM   9453  O  O   . ILE C 1 421 ? -17.095 7.854   25.262  1    108.95 ? 410 ILE C O   1 -0.157 0.072  0.063  
ATOM   9454  C  CB  . ILE C 1 421 ? -18.296 4.849   26.448  1    109.06 ? 410 ILE C CB  1 -0.168 0.044  0.066  
ATOM   9455  C  CG1 . ILE C 1 421 ? -19.529 4.423   27.261  1    97.34  ? 410 ILE C CG1 1 -0.179 0.041  0.068  
ATOM   9456  C  CG2 . ILE C 1 421 ? -17.163 5.233   27.42   1    105.68 ? 410 ILE C CG2 1 -0.157 0.048  0.068  
ATOM   9457  C  CD1 . ILE C 1 421 ? -19.195 3.548   28.454  1    98.94  ? 410 ILE C CD1 1 -0.176 0.033  0.071  
ATOM   9458  N  N   . GLU C 1 422 ? -16.65  5.996   24.082  1    106.62 ? 411 GLU C N   1 -0.153 0.055  0.06   
ATOM   9459  C  CA  . GLU C 1 422 ? -15.436 6.591   23.53   1    112.11 ? 411 GLU C CA  1 -0.141 0.06   0.059  
ATOM   9460  C  C   . GLU C 1 422 ? -15.738 7.916   22.83   1    112.13 ? 411 GLU C C   1 -0.144 0.073  0.057  
ATOM   9461  O  O   . GLU C 1 422 ? -14.975 8.883   22.957  1    112.37 ? 411 GLU C O   1 -0.137 0.081  0.057  
ATOM   9462  C  CB  . GLU C 1 422 ? -14.759 5.609   22.582  1    110.69 ? 411 GLU C CB  1 -0.135 0.051  0.056  
ATOM   9463  C  CG  . GLU C 1 422 ? -13.657 6.246   21.77   1    119.41 ? 411 GLU C CG  1 -0.125 0.057  0.054  
ATOM   9464  C  CD  . GLU C 1 422 ? -13.042 5.283   20.787  1    126.11 ? 411 GLU C CD  1 -0.12  0.048  0.052  
ATOM   9465  O  OE1 . GLU C 1 422 ? -13.056 4.066   21.081  1    121.98 ? 411 GLU C OE1 1 -0.12  0.037  0.053  
ATOM   9466  O  OE2 . GLU C 1 422 ? -12.558 5.742   19.724  1    132.45 ? 411 GLU C OE2 1 -0.115 0.053  0.049  
ATOM   9467  N  N   . LYS C 1 423 ? -16.861 7.986   22.111  1    109.35 ? 412 LYS C N   1 -0.155 0.073  0.055  
ATOM   9468  C  CA  . LYS C 1 423 ? -17.31  9.239   21.51   1    106.59 ? 412 LYS C CA  1 -0.159 0.085  0.054  
ATOM   9469  C  C   . LYS C 1 423 ? -17.439 10.332  22.57   1    106.73 ? 412 LYS C C   1 -0.16  0.095  0.056  
ATOM   9470  O  O   . LYS C 1 423 ? -16.725 11.342  22.542  1    99.84  ? 412 LYS C O   1 -0.153 0.104  0.056  
ATOM   9471  C  CB  . LYS C 1 423 ? -18.651 9.003   20.794  1    104.65 ? 412 LYS C CB  1 -0.171 0.083  0.052  
ATOM   9472  C  CG  . LYS C 1 423 ? -18.968 9.869   19.559  1    112.84 ? 412 LYS C CG  1 -0.174 0.09   0.049  
ATOM   9473  C  CD  . LYS C 1 423 ? -18.613 9.155   18.224  1    122.17 ? 412 LYS C CD  1 -0.171 0.084  0.046  
ATOM   9474  C  CE  . LYS C 1 423 ? -19.319 7.793   18.046  1    109.88 ? 412 LYS C CE  1 -0.177 0.071  0.045  
ATOM   9475  N  NZ  . LYS C 1 423 ? -18.532 6.916   17.123  1    101.29 ? 412 LYS C NZ  1 -0.17  0.063  0.043  
ATOM   9476  N  N   . GLN C 1 424 ? -18.303 10.102  23.559  1    111.91 ? 413 GLN C N   1 -0.168 0.093  0.059  
ATOM   9477  C  CA  . GLN C 1 424 ? -18.833 11.139  24.437  1    115    ? 413 GLN C CA  1 -0.173 0.102  0.061  
ATOM   9478  C  C   . GLN C 1 424 ? -17.986 11.403  25.683  1    111.13 ? 413 GLN C C   1 -0.165 0.104  0.064  
ATOM   9479  O  O   . GLN C 1 424 ? -17.678 12.56   25.997  1    110.28 ? 413 GLN C O   1 -0.162 0.115  0.065  
ATOM   9480  C  CB  . GLN C 1 424 ? -20.251 10.756  24.864  1    112.64 ? 413 GLN C CB  1 -0.186 0.099  0.062  
ATOM   9481  C  CG  . GLN C 1 424 ? -21.186 11.932  24.999  1    113.68 ? 413 GLN C CG  1 -0.194 0.109  0.062  
ATOM   9482  C  CD  . GLN C 1 424 ? -21.995 12.126  23.749  1    110.67 ? 413 GLN C CD  1 -0.202 0.111  0.059  
ATOM   9483  O  OE1 . GLN C 1 424 ? -21.689 11.527  22.723  1    113.56 ? 413 GLN C OE1 1 -0.199 0.106  0.057  
ATOM   9484  N  NE2 . GLN C 1 424 ? -23.044 12.944  23.823  1    106.77 ? 413 GLN C NE2 1 -0.211 0.119  0.059  
ATOM   9485  N  N   . LEU C 1 425 ? -17.631 10.353  26.42   1    115.11 ? 414 LEU C N   1 -0.162 0.095  0.066  
ATOM   9486  C  CA  . LEU C 1 425 ? -17.115 10.497  27.78   1    115.49 ? 414 LEU C CA  1 -0.157 0.096  0.069  
ATOM   9487  C  C   . LEU C 1 425 ? -15.609 10.339  27.873  1    117.24 ? 414 LEU C C   1 -0.143 0.095  0.07   
ATOM   9488  O  O   . LEU C 1 425 ? -14.992 10.887  28.792  1    119.65 ? 414 LEU C O   1 -0.137 0.1    0.072  
ATOM   9489  C  CB  . LEU C 1 425 ? -17.774 9.47    28.709  1    103.18 ? 414 LEU C CB  1 -0.163 0.087  0.072  
ATOM   9490  C  CG  . LEU C 1 425 ? -19.174 9.694   29.286  1    99.69  ? 414 LEU C CG  1 -0.176 0.089  0.073  
ATOM   9491  C  CD1 . LEU C 1 425 ? -20.142 10.205  28.282  1    108.31 ? 414 LEU C CD1 1 -0.185 0.094  0.071  
ATOM   9492  C  CD2 . LEU C 1 425 ? -19.692 8.386   29.84   1    110.14 ? 414 LEU C CD2 1 -0.18  0.077  0.075  
ATOM   9493  N  N   . LEU C 1 426 ? -15.015 9.616   26.962  1    120.21 ? 415 LEU C N   1 -0.138 0.088  0.067  
ATOM   9494  C  CA  . LEU C 1 426 ? -13.578 9.429   27.03   1    126.88 ? 415 LEU C CA  1 -0.124 0.086  0.067  
ATOM   9495  C  C   . LEU C 1 426 ? -12.841 10.665  26.516  1    133.55 ? 415 LEU C C   1 -0.118 0.098  0.066  
ATOM   9496  O  O   . LEU C 1 426 ? -13.297 11.31   25.563  1    123    ? 415 LEU C O   1 -0.122 0.104  0.064  
ATOM   9497  C  CB  . LEU C 1 426 ? -13.159 8.213   26.222  1    124.31 ? 415 LEU C CB  1 -0.121 0.075  0.065  
ATOM   9498  C  CG  . LEU C 1 426 ? -12.792 7.002   27.073  1    123.84 ? 415 LEU C CG  1 -0.117 0.064  0.068  
ATOM   9499  C  CD1 . LEU C 1 426 ? -13.877 6.704   28.088  1    116.88 ? 415 LEU C CD1 1 -0.127 0.061  0.07   
ATOM   9500  C  CD2 . LEU C 1 426 ? -12.563 5.81    26.163  1    123.6  ? 415 LEU C CD2 1 -0.115 0.053  0.065  
ATOM   9501  N  N   . PRO C 1 427 ? -11.707 11.008  27.137  1    143.43 ? 416 PRO C N   1 -0.107 0.101  0.068  
ATOM   9502  C  CA  . PRO C 1 427 ? -10.949 12.191  26.715  1    141.84 ? 416 PRO C CA  1 -0.1   0.112  0.067  
ATOM   9503  C  C   . PRO C 1 427 ? -10.616 12.162  25.227  1    141.81 ? 416 PRO C C   1 -0.097 0.111  0.063  
ATOM   9504  O  O   . PRO C 1 427 ? -10.478 11.1    24.613  1    138.07 ? 416 PRO C O   1 -0.096 0.102  0.061  
ATOM   9505  C  CB  . PRO C 1 427 ? -9.683  12.127  27.578  1    133.62 ? 416 PRO C CB  1 -0.089 0.111  0.069  
ATOM   9506  C  CG  . PRO C 1 427 ? -10.118 11.409  28.808  1    136.38 ? 416 PRO C CG  1 -0.093 0.105  0.072  
ATOM   9507  C  CD  . PRO C 1 427 ? -11.165 10.417  28.38   1    137.12 ? 416 PRO C CD  1 -0.102 0.095  0.071  
ATOM   9508  N  N   . LYS C 1 428 ? -10.494 13.359  24.662  1    143.96 ? 417 LYS C N   1 -0.096 0.122  0.062  
ATOM   9509  C  CA  . LYS C 1 428 ? -10.277 13.552  23.234  1    143.99 ? 417 LYS C CA  1 -0.094 0.124  0.058  
ATOM   9510  C  C   . LYS C 1 428 ? -8.801  13.326  22.914  1    147.19 ? 417 LYS C C   1 -0.081 0.122  0.057  
ATOM   9511  O  O   . LYS C 1 428 ? -7.942  14.108  23.339  1    148.89 ? 417 LYS C O   1 -0.073 0.129  0.058  
ATOM   9512  C  CB  . LYS C 1 428 ? -10.735 14.956  22.849  1    141.92 ? 417 LYS C CB  1 -0.098 0.137  0.057  
ATOM   9513  C  CG  . LYS C 1 428 ? -12.112 15.34   23.418  1    141.55 ? 417 LYS C CG  1 -0.111 0.141  0.058  
ATOM   9514  C  CD  . LYS C 1 428 ? -13.249 14.806  22.537  1    141.01 ? 417 LYS C CD  1 -0.121 0.136  0.056  
ATOM   9515  C  CE  . LYS C 1 428 ? -14.621 15.177  23.087  1    135.19 ? 417 LYS C CE  1 -0.134 0.139  0.058  
ATOM   9516  N  NZ  . LYS C 1 428 ? -14.9   14.489  24.382  1    138.03 ? 417 LYS C NZ  1 -0.137 0.133  0.061  
ATOM   9517  N  N   . ASP C 1 429 ? -8.503  12.253  22.174  1    146.24 ? 418 ASP C N   1 -0.078 0.112  0.055  
ATOM   9518  C  CA  . ASP C 1 429 ? -7.129  11.939  21.769  1    143.47 ? 418 ASP C CA  1 -0.065 0.109  0.054  
ATOM   9519  C  C   . ASP C 1 429 ? -6.954  12.024  20.244  1    140.52 ? 418 ASP C C   1 -0.064 0.11   0.051  
ATOM   9520  O  O   . ASP C 1 429 ? -7.575  11.275  19.482  1    133.6  ? 418 ASP C O   1 -0.069 0.103  0.049  
ATOM   9521  C  CB  . ASP C 1 429 ? -6.724  10.553  22.281  1    129.05 ? 418 ASP C CB  1 -0.062 0.097  0.056  
ATOM   9522  N  N   . GLU D 1 38  ? -45.007 63.652  -10.539 1    129.81 ? 27  GLU D N   1 -0.412 0.583  -0.026 
ATOM   9523  C  CA  . GLU D 1 38  ? -44.213 63.531  -11.767 1    137.22 ? 27  GLU D CA  1 -0.405 0.582  -0.029 
ATOM   9524  C  C   . GLU D 1 38  ? -42.766 64.015  -11.549 1    133.01 ? 27  GLU D C   1 -0.392 0.587  -0.029 
ATOM   9525  O  O   . GLU D 1 38  ? -41.881 63.766  -12.376 1    121.22 ? 27  GLU D O   1 -0.384 0.584  -0.031 
ATOM   9526  C  CB  . GLU D 1 38  ? -44.874 64.313  -12.921 1    136.13 ? 27  GLU D CB  1 -0.411 0.589  -0.032 
ATOM   9527  C  CG  . GLU D 1 38  ? -44.148 64.219  -14.266 1    140.52 ? 27  GLU D CG  1 -0.405 0.589  -0.036 
ATOM   9528  C  CD  . GLU D 1 38  ? -44.481 65.373  -15.218 1    153.93 ? 27  GLU D CD  1 -0.408 0.599  -0.038 
ATOM   9529  O  OE1 . GLU D 1 38  ? -45.416 66.145  -14.9   1    159.11 ? 27  GLU D OE1 1 -0.416 0.606  -0.037 
ATOM   9530  O  OE2 . GLU D 1 38  ? -43.808 65.507  -16.277 1    139.91 ? 27  GLU D OE2 1 -0.401 0.6    -0.041 
ATOM   9531  N  N   . GLU D 1 39  ? -42.526 64.699  -10.422 1    132.98 ? 28  GLU D N   1 -0.39  0.593  -0.026 
ATOM   9532  C  CA  . GLU D 1 39  ? -41.193 65.205  -10.099 1    128.38 ? 28  GLU D CA  1 -0.377 0.598  -0.025 
ATOM   9533  C  C   . GLU D 1 39  ? -40.302 64.15   -9.436  1    118.96 ? 28  GLU D C   1 -0.369 0.588  -0.024 
ATOM   9534  O  O   . GLU D 1 39  ? -39.077 64.32   -9.38   1    112.33 ? 28  GLU D O   1 -0.358 0.589  -0.023 
ATOM   9535  C  CB  . GLU D 1 39  ? -41.341 66.46   -9.226  1    129.37 ? 28  GLU D CB  1 -0.379 0.609  -0.023 
ATOM   9536  C  CG  . GLU D 1 39  ? -40.046 67.059  -8.683  1    132.68 ? 28  GLU D CG  1 -0.367 0.615  -0.022 
ATOM   9537  C  CD  . GLU D 1 39  ? -39.811 66.689  -7.214  1    145.39 ? 28  GLU D CD  1 -0.365 0.611  -0.018 
ATOM   9538  O  OE1 . GLU D 1 39  ? -38.637 66.485  -6.818  1    140.76 ? 28  GLU D OE1 1 -0.354 0.609  -0.017 
ATOM   9539  O  OE2 . GLU D 1 39  ? -40.808 66.603  -6.454  1    150.66 ? 28  GLU D OE2 1 -0.374 0.61   -0.016 
ATOM   9540  N  N   . CYS D 1 40  ? -40.873 63.045  -8.976  1    115.43 ? 29  CYS D N   1 -0.375 0.578  -0.022 
ATOM   9541  C  CA  . CYS D 1 40  ? -40.072 61.937  -8.487  1    118.03 ? 29  CYS D CA  1 -0.367 0.568  -0.021 
ATOM   9542  C  C   . CYS D 1 40  ? -40.879 60.661  -8.636  1    121.92 ? 29  CYS D C   1 -0.375 0.556  -0.022 
ATOM   9543  O  O   . CYS D 1 40  ? -42.088 60.659  -8.389  1    122.84 ? 29  CYS D O   1 -0.386 0.556  -0.021 
ATOM   9544  C  CB  . CYS D 1 40  ? -39.666 62.131  -7.022  1    126.52 ? 29  CYS D CB  1 -0.364 0.569  -0.018 
ATOM   9545  S  SG  . CYS D 1 40  ? -38.817 60.708  -6.296  1    118.4  ? 29  CYS D SG  1 -0.356 0.556  -0.016 
ATOM   9546  N  N   . ALA D 1 41  ? -40.203 59.586  -9.045  1    120.64 ? 30  ALA D N   1 -0.368 0.546  -0.023 
ATOM   9547  C  CA  . ALA D 1 41  ? -40.83  58.28   -9.199  1    118.71 ? 30  ALA D CA  1 -0.374 0.534  -0.023 
ATOM   9548  C  C   . ALA D 1 41  ? -39.823 57.19   -8.834  1    114    ? 30  ALA D C   1 -0.365 0.524  -0.022 
ATOM   9549  O  O   . ALA D 1 41  ? -38.627 57.308  -9.135  1    111.32 ? 30  ALA D O   1 -0.354 0.525  -0.023 
ATOM   9550  C  CB  . ALA D 1 41  ? -41.35  58.078  -10.632 1    110.24 ? 30  ALA D CB  1 -0.379 0.532  -0.027 
ATOM   9551  N  N   . ILE D 1 42  ? -40.304 56.132  -8.184  1    104.15 ? 31  ILE D N   1 -0.369 0.514  -0.02  
ATOM   9552  C  CA  . ILE D 1 42  ? -39.464 54.982  -7.863  1    106.11 ? 31  ILE D CA  1 -0.362 0.504  -0.02  
ATOM   9553  C  C   . ILE D 1 42  ? -39.925 53.809  -8.716  1    104.42 ? 31  ILE D C   1 -0.366 0.493  -0.022 
ATOM   9554  O  O   . ILE D 1 42  ? -41.088 53.391  -8.644  1    100.45 ? 31  ILE D O   1 -0.377 0.489  -0.022 
ATOM   9555  C  CB  . ILE D 1 42  ? -39.49  54.645  -6.362  1    109.75 ? 31  ILE D CB  1 -0.362 0.501  -0.016 
ATOM   9556  C  CG1 . ILE D 1 42  ? -39     55.853  -5.556  1    102.21 ? 31  ILE D CG1 1 -0.357 0.512  -0.014 
ATOM   9557  C  CG2 . ILE D 1 42  ? -38.629 53.41   -6.052  1    100.44 ? 31  ILE D CG2 1 -0.354 0.489  -0.015 
ATOM   9558  C  CD1 . ILE D 1 42  ? -38.362 55.498  -4.267  1    95.36  ? 31  ILE D CD1 1 -0.352 0.509  -0.011 
ATOM   9559  N  N   . GLN D 1 43  ? -39.003 53.285  -9.525  1    106.35 ? 32  GLN D N   1 -0.357 0.488  -0.024 
ATOM   9560  C  CA  . GLN D 1 43  ? -39.31  52.296  -10.553 1    110.94 ? 32  GLN D CA  1 -0.36  0.479  -0.026 
ATOM   9561  C  C   . GLN D 1 43  ? -38.893 50.915  -10.07  1    107.59 ? 32  GLN D C   1 -0.356 0.467  -0.025 
ATOM   9562  O  O   . GLN D 1 43  ? -37.72  50.69   -9.748  1    106.88 ? 32  GLN D O   1 -0.346 0.465  -0.024 
ATOM   9563  C  CB  . GLN D 1 43  ? -38.606 52.625  -11.873 1    106.66 ? 32  GLN D CB  1 -0.354 0.482  -0.03  
ATOM   9564  C  CG  . GLN D 1 43  ? -38.629 51.486  -12.894 1    109.51 ? 32  GLN D CG  1 -0.354 0.472  -0.032 
ATOM   9565  C  CD  . GLN D 1 43  ? -38.155 51.909  -14.298 1    114.58 ? 32  GLN D CD  1 -0.35  0.476  -0.036 
ATOM   9566  O  OE1 . GLN D 1 43  ? -38.347 53.058  -14.726 1    113.11 ? 32  GLN D OE1 1 -0.351 0.486  -0.037 
ATOM   9567  N  NE2 . GLN D 1 43  ? -37.533 50.973  -15.016 1    107.93 ? 32  GLN D NE2 1 -0.344 0.467  -0.037 
ATOM   9568  N  N   . ILE D 1 44  ? -39.847 49.992  -10.045 1    106.53 ? 33  ILE D N   1 -0.365 0.458  -0.025 
ATOM   9569  C  CA  . ILE D 1 44  ? -39.558 48.614  -9.671  1    107.2  ? 33  ILE D CA  1 -0.363 0.446  -0.024 
ATOM   9570  C  C   . ILE D 1 44  ? -39.988 47.7    -10.812 1    102.97 ? 33  ILE D C   1 -0.366 0.437  -0.027 
ATOM   9571  O  O   . ILE D 1 44  ? -40.872 48.07   -11.599 1    98.74  ? 33  ILE D O   1 -0.375 0.441  -0.029 
ATOM   9572  C  CB  . ILE D 1 44  ? -40.256 48.236  -8.363  1    102.72 ? 33  ILE D CB  1 -0.369 0.442  -0.021 
ATOM   9573  C  CG1 . ILE D 1 44  ? -41.75  48.56   -8.452  1    100.89 ? 33  ILE D CG1 1 -0.383 0.445  -0.021 
ATOM   9574  C  CG2 . ILE D 1 44  ? -39.64  48.976  -7.206  1    106.02 ? 33  ILE D CG2 1 -0.363 0.449  -0.018 
ATOM   9575  C  CD1 . ILE D 1 44  ? -42.606 47.76   -7.498  1    93.79  ? 33  ILE D CD1 1 -0.39  0.438  -0.019 
ATOM   9576  N  N   . PRO D 1 45  ? -39.397 46.517  -10.945 1    97.03  ? 34  PRO D N   1 -0.361 0.426  -0.027 
ATOM   9577  C  CA  . PRO D 1 45  ? -39.948 45.527  -11.873 1    98.86  ? 34  PRO D CA  1 -0.366 0.417  -0.03  
ATOM   9578  C  C   . PRO D 1 45  ? -41.348 45.128  -11.448 1    100.68 ? 34  PRO D C   1 -0.379 0.414  -0.029 
ATOM   9579  O  O   . PRO D 1 45  ? -41.665 45.072  -10.258 1    105.84 ? 34  PRO D O   1 -0.382 0.413  -0.026 
ATOM   9580  C  CB  . PRO D 1 45  ? -38.978 44.342  -11.754 1    98.96  ? 34  PRO D CB  1 -0.357 0.406  -0.029 
ATOM   9581  C  CG  . PRO D 1 45  ? -37.759 44.902  -11.063 1    98.61  ? 34  PRO D CG  1 -0.346 0.411  -0.028 
ATOM   9582  C  CD  . PRO D 1 45  ? -38.247 45.996  -10.196 1    98.08  ? 34  PRO D CD  1 -0.351 0.422  -0.025 
ATOM   9583  N  N   . SER D 1 46  ? -42.19  44.847  -12.432 1    104.1  ? 35  SER D N   1 -0.387 0.411  -0.031 
ATOM   9584  C  CA  . SER D 1 46  ? -43.526 44.363  -12.13  1    106.93 ? 35  SER D CA  1 -0.399 0.407  -0.03  
ATOM   9585  C  C   . SER D 1 46  ? -43.431 42.983  -11.486 1    102.01 ? 35  SER D C   1 -0.398 0.394  -0.029 
ATOM   9586  O  O   . SER D 1 46  ? -42.348 42.409  -11.332 1    94.99  ? 35  SER D O   1 -0.388 0.389  -0.028 
ATOM   9587  C  CB  . SER D 1 46  ? -44.383 44.329  -13.395 1    110.61 ? 35  SER D CB  1 -0.407 0.406  -0.033 
ATOM   9588  O  OG  . SER D 1 46  ? -44.029 43.248  -14.244 1    109.93 ? 35  SER D OG  1 -0.403 0.396  -0.036 
ATOM   9589  N  N   . GLU D 1 47  ? -44.582 42.444  -11.099 1    105.79 ? 36  GLU D N   1 -0.409 0.389  -0.028 
ATOM   9590  C  CA  . GLU D 1 47  ? -44.6   41.107  -10.523 1    108.97 ? 36  GLU D CA  1 -0.409 0.377  -0.026 
ATOM   9591  C  C   . GLU D 1 47  ? -44.052 40.102  -11.528 1    108.13 ? 36  GLU D C   1 -0.404 0.368  -0.029 
ATOM   9592  O  O   . GLU D 1 47  ? -42.956 39.567  -11.332 1    104.3  ? 36  GLU D O   1 -0.394 0.363  -0.028 
ATOM   9593  C  CB  . GLU D 1 47  ? -46.012 40.727  -10.082 1    120.23 ? 36  GLU D CB  1 -0.422 0.373  -0.025 
ATOM   9594  C  CG  . GLU D 1 47  ? -46.054 39.583  -9.074  1    122.01 ? 36  GLU D CG  1 -0.422 0.363  -0.023 
ATOM   9595  C  CD  . GLU D 1 47  ? -46.931 39.901  -7.873  1    136.25 ? 36  GLU D CD  1 -0.43  0.366  -0.02  
ATOM   9596  O  OE1 . GLU D 1 47  ? -47.217 41.099  -7.649  1    139.03 ? 36  GLU D OE1 1 -0.433 0.377  -0.019 
ATOM   9597  O  OE2 . GLU D 1 47  ? -47.334 38.961  -7.15   1    142.49 ? 36  GLU D OE2 1 -0.434 0.357  -0.018 
ATOM   9598  N  N   . ILE D 1 48  ? -44.788 39.879  -12.624 1    108.49 ? 37  ILE D N   1 -0.41  0.365  -0.032 
ATOM   9599  C  CA  . ILE D 1 48  ? -44.381 38.903  -13.637 1    104.32 ? 37  ILE D CA  1 -0.407 0.357  -0.034 
ATOM   9600  C  C   . ILE D 1 48  ? -42.99  39.217  -14.188 1    98.53  ? 37  ILE D C   1 -0.394 0.359  -0.035 
ATOM   9601  O  O   . ILE D 1 48  ? -42.211 38.309  -14.502 1    96.4   ? 37  ILE D O   1 -0.387 0.351  -0.036 
ATOM   9602  C  CB  . ILE D 1 48  ? -45.44  38.832  -14.76  1    103.17 ? 37  ILE D CB  1 -0.416 0.356  -0.037 
ATOM   9603  C  CG1 . ILE D 1 48  ? -45.132 37.7    -15.751 1    101.31 ? 37  ILE D CG1 1 -0.414 0.345  -0.039 
ATOM   9604  C  CG2 . ILE D 1 48  ? -45.584 40.189  -15.469 1    101.91 ? 37  ILE D CG2 1 -0.418 0.368  -0.039 
ATOM   9605  C  CD1 . ILE D 1 48  ? -45.576 36.306  -15.293 1    97.84  ? 37  ILE D CD1 1 -0.418 0.333  -0.038 
ATOM   9606  N  N   . ASP D 1 49  ? -42.656 40.507  -14.31  1    92.44  ? 38  ASP D N   1 -0.391 0.371  -0.036 
ATOM   9607  C  CA  . ASP D 1 49  ? -41.341 40.875  -14.823 1    93.86  ? 38  ASP D CA  1 -0.379 0.375  -0.037 
ATOM   9608  C  C   . ASP D 1 49  ? -40.239 40.338  -13.924 1    94.89  ? 38  ASP D C   1 -0.369 0.37   -0.035 
ATOM   9609  O  O   . ASP D 1 49  ? -39.267 39.738  -14.396 1    91.32  ? 38  ASP D O   1 -0.36  0.364  -0.036 
ATOM   9610  C  CB  . ASP D 1 49  ? -41.237 42.394  -14.954 1    101.19 ? 38  ASP D CB  1 -0.378 0.389  -0.037 
ATOM   9611  C  CG  . ASP D 1 49  ? -41.612 42.91   -16.35  1    106.68 ? 38  ASP D CG  1 -0.381 0.393  -0.041 
ATOM   9612  O  OD1 . ASP D 1 49  ? -42.675 42.516  -16.904 1    103.71 ? 38  ASP D OD1 1 -0.391 0.39   -0.042 
ATOM   9613  O  OD2 . ASP D 1 49  ? -40.832 43.737  -16.875 1    103.06 ? 38  ASP D OD2 1 -0.374 0.401  -0.042 
ATOM   9614  N  N   . ASN D 1 50  ? -40.377 40.558  -12.61  1    105.36 ? 39  ASN D N   1 -0.37  0.372  -0.031 
ATOM   9615  C  CA  . ASN D 1 50  ? -39.434 40.019  -11.636 1    100.41 ? 39  ASN D CA  1 -0.361 0.367  -0.029 
ATOM   9616  C  C   . ASN D 1 50  ? -39.454 38.496  -11.634 1    99.64  ? 39  ASN D C   1 -0.362 0.353  -0.029 
ATOM   9617  O  O   . ASN D 1 50  ? -38.433 37.866  -11.338 1    99.01  ? 39  ASN D O   1 -0.352 0.347  -0.028 
ATOM   9618  C  CB  . ASN D 1 50  ? -39.757 40.601  -10.247 1    105.9  ? 39  ASN D CB  1 -0.364 0.372  -0.026 
ATOM   9619  C  CG  . ASN D 1 50  ? -38.978 39.934  -9.094  1    102.95 ? 39  ASN D CG  1 -0.357 0.366  -0.023 
ATOM   9620  O  OD1 . ASN D 1 50  ? -39.578 39.494  -8.105  1    101.05 ? 39  ASN D OD1 1 -0.363 0.362  -0.02  
ATOM   9621  N  ND2 . ASN D 1 50  ? -37.65  39.876  -9.212  1    98.72  ? 39  ASN D ND2 1 -0.345 0.365  -0.023 
ATOM   9622  N  N   . GLU D 1 51  ? -40.589 37.889  -12.001 1    102.26 ? 40  GLU D N   1 -0.372 0.347  -0.03  
ATOM   9623  C  CA  . GLU D 1 51  ? -40.707 36.435  -12.036 1    104.8  ? 40  GLU D CA  1 -0.373 0.334  -0.03  
ATOM   9624  C  C   . GLU D 1 51  ? -39.83  35.79   -13.114 1    103.4  ? 40  GLU D C   1 -0.365 0.328  -0.033 
ATOM   9625  O  O   . GLU D 1 51  ? -39.651 34.566  -13.088 1    104.11 ? 40  GLU D O   1 -0.363 0.317  -0.033 
ATOM   9626  C  CB  . GLU D 1 51  ? -42.174 36.017  -12.244 1    107.18 ? 40  GLU D CB  1 -0.386 0.33   -0.031 
ATOM   9627  C  CG  . GLU D 1 51  ? -43.153 36.605  -11.241 1    106.68 ? 40  GLU D CG  1 -0.395 0.335  -0.028 
ATOM   9628  C  CD  . GLU D 1 51  ? -43.807 35.57   -10.341 1    122.98 ? 40  GLU D CD  1 -0.401 0.326  -0.026 
ATOM   9629  O  OE1 . GLU D 1 51  ? -43.769 34.379  -10.721 1    120.44 ? 40  GLU D OE1 1 -0.401 0.315  -0.027 
ATOM   9630  O  OE2 . GLU D 1 51  ? -44.354 35.95   -9.259  1    125.53 ? 40  GLU D OE2 1 -0.406 0.329  -0.023 
ATOM   9631  N  N   . GLN D 1 52  ? -39.263 36.559  -14.047 1    101.23 ? 41  GLN D N   1 -0.36  0.335  -0.035 
ATOM   9632  C  CA  . GLN D 1 52  ? -38.436 35.967  -15.092 1    101.93 ? 41  GLN D CA  1 -0.352 0.33   -0.038 
ATOM   9633  C  C   . GLN D 1 52  ? -36.941 36.168  -14.843 1    97.19  ? 41  GLN D C   1 -0.339 0.331  -0.037 
ATOM   9634  O  O   . GLN D 1 52  ? -36.143 36.091  -15.783 1    95.03  ? 41  GLN D O   1 -0.331 0.331  -0.039 
ATOM   9635  C  CB  . GLN D 1 52  ? -38.81  36.509  -16.482 1    93.98  ? 41  GLN D CB  1 -0.356 0.335  -0.041 
ATOM   9636  C  CG  . GLN D 1 52  ? -40.293 36.614  -16.815 1    89.36  ? 41  GLN D CG  1 -0.369 0.336  -0.042 
ATOM   9637  C  CD  . GLN D 1 52  ? -41.046 35.344  -16.499 1    100.97 ? 41  GLN D CD  1 -0.376 0.324  -0.041 
ATOM   9638  O  OE1 . GLN D 1 52  ? -40.554 34.236  -16.736 1    101.6  ? 41  GLN D OE1 1 -0.372 0.314  -0.042 
ATOM   9639  N  NE2 . GLN D 1 52  ? -42.24  35.494  -15.92  1    106.18 ? 41  GLN D NE2 1 -0.387 0.325  -0.04  
ATOM   9640  N  N   . MET D 1 53  ? -36.532 36.395  -13.601 1    99.13  ? 42  MET D N   1 -0.335 0.334  -0.034 
ATOM   9641  C  CA  . MET D 1 53  ? -35.131 36.681  -13.327 1    98.68  ? 42  MET D CA  1 -0.322 0.336  -0.033 
ATOM   9642  C  C   . MET D 1 53  ? -34.415 35.544  -12.596 1    98.7   ? 42  MET D C   1 -0.315 0.326  -0.031 
ATOM   9643  O  O   . MET D 1 53  ? -33.211 35.663  -12.325 1    98.24  ? 42  MET D O   1 -0.304 0.327  -0.031 
ATOM   9644  C  CB  . MET D 1 53  ? -35.027 38.01   -12.56  1    92.79  ? 42  MET D CB  1 -0.321 0.348  -0.031 
ATOM   9645  C  CG  . MET D 1 53  ? -36.023 39.075  -13.111 1    102.91 ? 42  MET D CG  1 -0.33  0.358  -0.033 
ATOM   9646  S  SD  . MET D 1 53  ? -36.001 40.724  -12.351 1    106.97 ? 42  MET D SD  1 -0.33  0.373  -0.031 
ATOM   9647  C  CE  . MET D 1 53  ? -34.342 41.123  -12.776 1    88.96  ? 42  MET D CE  1 -0.315 0.377  -0.032 
ATOM   9648  N  N   . GLN D 1 54  ? -35.105 34.432  -12.305 1    94.19  ? 43  GLN D N   1 -0.322 0.316  -0.031 
ATOM   9649  C  CA  . GLN D 1 54  ? -34.446 33.257  -11.742 1    93.2   ? 43  GLN D CA  1 -0.316 0.305  -0.029 
ATOM   9650  C  C   . GLN D 1 54  ? -33.249 32.843  -12.58  1    100.1  ? 43  GLN D C   1 -0.305 0.301  -0.031 
ATOM   9651  O  O   . GLN D 1 54  ? -33.309 32.831  -13.811 1    99.29  ? 43  GLN D O   1 -0.305 0.301  -0.034 
ATOM   9652  C  CB  . GLN D 1 54  ? -35.411 32.084  -11.665 1    97.37  ? 43  GLN D CB  1 -0.325 0.294  -0.029 
ATOM   9653  C  CG  . GLN D 1 54  ? -36.201 31.989  -10.392 1    109.78 ? 43  GLN D CG  1 -0.332 0.293  -0.026 
ATOM   9654  C  CD  . GLN D 1 54  ? -37.523 31.284  -10.616 1    115.1  ? 43  GLN D CD  1 -0.344 0.287  -0.027 
ATOM   9655  O  OE1 . GLN D 1 54  ? -38.215 30.898  -9.662  1    105.52 ? 43  GLN D OE1 1 -0.35  0.283  -0.024 
ATOM   9656  N  NE2 . GLN D 1 54  ? -37.894 31.126  -11.9   1    118.57 ? 43  GLN D NE2 1 -0.347 0.285  -0.03  
ATOM   9657  N  N   . ARG D 1 55  ? -32.168 32.486  -11.892 1    101.08 ? 44  ARG D N   1 -0.295 0.298  -0.03  
ATOM   9658  C  CA  . ARG D 1 55  ? -30.961 31.895  -12.473 1    100    ? 44  ARG D CA  1 -0.284 0.292  -0.031 
ATOM   9659  C  C   . ARG D 1 55  ? -30.045 32.983  -12.989 1    96.68  ? 44  ARG D C   1 -0.275 0.302  -0.032 
ATOM   9660  O  O   . ARG D 1 55  ? -28.839 32.752  -13.142 1    97.11  ? 44  ARG D O   1 -0.264 0.3    -0.033 
ATOM   9661  C  CB  . ARG D 1 55  ? -31.273 30.881  -13.581 1    98.78  ? 44  ARG D CB  1 -0.287 0.283  -0.034 
ATOM   9662  C  CG  . ARG D 1 55  ? -31.526 29.479  -13.05  1    106.22 ? 44  ARG D CG  1 -0.289 0.27   -0.033 
ATOM   9663  C  CD  . ARG D 1 55  ? -32.435 29.548  -11.825 1    113.76 ? 44  ARG D CD  1 -0.297 0.271  -0.03  
ATOM   9664  N  NE  . ARG D 1 55  ? -32.379 28.402  -10.925 1    121.87 ? 44  ARG D NE  1 -0.297 0.26   -0.027 
ATOM   9665  C  CZ  . ARG D 1 55  ? -33.262 27.41   -10.926 1    123.93 ? 44  ARG D CZ  1 -0.305 0.251  -0.027 
ATOM   9666  N  NH1 . ARG D 1 55  ? -34.187 27.31   -11.878 1    114.69 ? 44  ARG D NH1 1 -0.313 0.25   -0.03  
ATOM   9667  N  NH2 . ARG D 1 55  ? -33.225 26.505  -9.943  1    115.25 ? 44  ARG D NH2 1 -0.304 0.243  -0.025 
ATOM   9668  N  N   . MET D 1 56  ? -30.604 34.173  -13.244 1    94.05  ? 45  MET D N   1 -0.28  0.313  -0.033 
ATOM   9669  C  CA  . MET D 1 56  ? -29.77  35.32   -13.572 1    99.71  ? 45  MET D CA  1 -0.273 0.324  -0.034 
ATOM   9670  C  C   . MET D 1 56  ? -28.804 35.565  -12.42  1    104.75 ? 45  MET D C   1 -0.264 0.326  -0.031 
ATOM   9671  O  O   . MET D 1 56  ? -29.231 35.981  -11.34  1    97.66  ? 45  MET D O   1 -0.268 0.33   -0.028 
ATOM   9672  C  CB  . MET D 1 56  ? -30.619 36.563  -13.823 1    97.03  ? 45  MET D CB  1 -0.281 0.335  -0.035 
ATOM   9673  C  CG  . MET D 1 56  ? -31.702 36.373  -14.863 1    105.47 ? 45  MET D CG  1 -0.291 0.333  -0.037 
ATOM   9674  S  SD  . MET D 1 56  ? -31.967 37.849  -15.872 1    108.95 ? 45  MET D SD  1 -0.293 0.347  -0.04  
ATOM   9675  C  CE  . MET D 1 56  ? -30.293 38.109  -16.465 1    106.55 ? 45  MET D CE  1 -0.278 0.349  -0.041 
ATOM   9676  N  N   . PRO D 1 57  ? -27.502 35.354  -12.612 1    105.07 ? 46  PRO D N   1 -0.252 0.324  -0.031 
ATOM   9677  C  CA  . PRO D 1 57  ? -26.588 35.35   -11.473 1    100.7  ? 46  PRO D CA  1 -0.244 0.324  -0.029 
ATOM   9678  C  C   . PRO D 1 57  ? -26.481 36.726  -10.849 1    107.89 ? 46  PRO D C   1 -0.243 0.337  -0.027 
ATOM   9679  O  O   . PRO D 1 57  ? -26.577 37.753  -11.531 1    107.39 ? 46  PRO D O   1 -0.244 0.346  -0.029 
ATOM   9680  C  CB  . PRO D 1 57  ? -25.256 34.937  -12.098 1    100.81 ? 46  PRO D CB  1 -0.231 0.32   -0.03  
ATOM   9681  C  CG  . PRO D 1 57  ? -25.302 35.603  -13.408 1    106.3  ? 46  PRO D CG  1 -0.232 0.326  -0.033 
ATOM   9682  C  CD  . PRO D 1 57  ? -26.758 35.492  -13.875 1    105.08 ? 46  PRO D CD  1 -0.245 0.325  -0.035 
ATOM   9683  N  N   . ALA D 1 58  ? -26.275 36.726  -9.536  1    104.98 ? 47  ALA D N   1 -0.241 0.337  -0.024 
ATOM   9684  C  CA  . ALA D 1 58  ? -25.96  37.917  -8.779  1    99.81  ? 47  ALA D CA  1 -0.238 0.347  -0.022 
ATOM   9685  C  C   . ALA D 1 58  ? -24.714 37.589  -7.969  1    104.15 ? 47  ALA D C   1 -0.226 0.344  -0.02  
ATOM   9686  O  O   . ALA D 1 58  ? -24.221 36.472  -8.042  1    103.15 ? 47  ALA D O   1 -0.222 0.334  -0.02  
ATOM   9687  C  CB  . ALA D 1 58  ? -27.139 38.32   -7.876  1    101.93 ? 47  ALA D CB  1 -0.249 0.351  -0.02  
ATOM   9688  N  N   . GLY D 1 59  ? -24.191 38.558  -7.204  1    106.16 ? 48  GLY D N   1 -0.222 0.353  -0.018 
ATOM   9689  C  CA  . GLY D 1 59  ? -22.981 38.317  -6.4    1    109.37 ? 48  GLY D CA  1 -0.211 0.351  -0.016 
ATOM   9690  C  C   . GLY D 1 59  ? -23.133 37.756  -4.966  1    107.44 ? 48  GLY D C   1 -0.212 0.346  -0.012 
ATOM   9691  O  O   . GLY D 1 59  ? -22.136 37.397  -4.323  1    100.74 ? 48  GLY D O   1 -0.203 0.343  -0.011 
ATOM   9692  N  N   . GLY D 1 60  ? -24.357 37.672  -4.456  1    107.52 ? 49  GLY D N   1 -0.223 0.345  -0.011 
ATOM   9693  C  CA  . GLY D 1 60  ? -24.608 37.254  -3.099  1    106.89 ? 49  GLY D CA  1 -0.226 0.341  -0.008 
ATOM   9694  C  C   . GLY D 1 60  ? -24.901 35.776  -2.988  1    103.52 ? 49  GLY D C   1 -0.228 0.328  -0.007 
ATOM   9695  O  O   . GLY D 1 60  ? -24.518 34.972  -3.841  1    94.75  ? 49  GLY D O   1 -0.225 0.32   -0.01  
ATOM   9696  N  N   . GLU D 1 61  ? -25.556 35.407  -1.891  1    111.72 ? 50  GLU D N   1 -0.234 0.324  -0.005 
ATOM   9697  C  CA  . GLU D 1 61  ? -26.042 34.05   -1.728  1    110.67 ? 50  GLU D CA  1 -0.239 0.312  -0.004 
ATOM   9698  C  C   . GLU D 1 61  ? -27.277 33.773  -2.563  1    108.71 ? 50  GLU D C   1 -0.25  0.31   -0.006 
ATOM   9699  O  O   . GLU D 1 61  ? -27.784 32.648  -2.524  1    113.33 ? 50  GLU D O   1 -0.255 0.299  -0.006 
ATOM   9700  C  CB  . GLU D 1 61  ? -26.362 33.77   -0.253  1    103.62 ? 50  GLU D CB  1 -0.242 0.309  -0.001 
ATOM   9701  C  CG  . GLU D 1 61  ? -25.267 32.961  0.448   1    115.78 ? 50  GLU D CG  1 -0.232 0.302  0.001  
ATOM   9702  C  CD  . GLU D 1 61  ? -25.406 32.875  1.997   1    126.52 ? 50  GLU D CD  1 -0.233 0.301  0.005  
ATOM   9703  O  OE1 . GLU D 1 61  ? -26.541 32.909  2.537   1    119.04 ? 50  GLU D OE1 1 -0.243 0.302  0.006  
ATOM   9704  O  OE2 . GLU D 1 61  ? -24.362 32.756  2.674   1    122.69 ? 50  GLU D OE2 1 -0.223 0.3    0.007  
ATOM   9705  N  N   . GLU D 1 62  ? -27.793 34.769  -3.279  1    101.84 ? 51  GLU D N   1 -0.255 0.319  -0.008 
ATOM   9706  C  CA  . GLU D 1 62  ? -29.095 34.656  -3.918  1    106.59 ? 51  GLU D CA  1 -0.267 0.318  -0.01  
ATOM   9707  C  C   . GLU D 1 62  ? -28.974 35.29   -5.286  1    103.68 ? 51  GLU D C   1 -0.266 0.323  -0.013 
ATOM   9708  O  O   . GLU D 1 62  ? -28.1   36.128  -5.509  1    107.58 ? 51  GLU D O   1 -0.258 0.331  -0.014 
ATOM   9709  C  CB  . GLU D 1 62  ? -30.211 35.335  -3.093  1    102.93 ? 51  GLU D CB  1 -0.277 0.324  -0.008 
ATOM   9710  C  CG  . GLU D 1 62  ? -29.955 36.832  -2.793  1    106.12 ? 51  GLU D CG  1 -0.275 0.338  -0.007 
ATOM   9711  C  CD  . GLU D 1 62  ? -31.024 37.48   -1.89   1    104.19 ? 51  GLU D CD  1 -0.284 0.343  -0.005 
ATOM   9712  O  OE1 . GLU D 1 62  ? -31.061 38.742  -1.833  1    97.95  ? 51  GLU D OE1 1 -0.285 0.355  -0.005 
ATOM   9713  O  OE2 . GLU D 1 62  ? -31.811 36.734  -1.245  1    103.33 ? 51  GLU D OE2 1 -0.292 0.337  -0.003 
ATOM   9714  N  N   . ASP D 1 63  ? -29.855 34.885  -6.198  1    99.64  ? 52  ASP D N   1 -0.274 0.32   -0.015 
ATOM   9715  C  CA  . ASP D 1 63  ? -29.766 35.332  -7.585  1    97.36  ? 52  ASP D CA  1 -0.273 0.324  -0.019 
ATOM   9716  C  C   . ASP D 1 63  ? -30.456 36.688  -7.729  1    98.75  ? 52  ASP D C   1 -0.279 0.336  -0.019 
ATOM   9717  O  O   . ASP D 1 63  ? -30.835 37.319  -6.738  1    105.14 ? 52  ASP D O   1 -0.283 0.342  -0.017 
ATOM   9718  C  CB  . ASP D 1 63  ? -30.35  34.273  -8.514  1    96.84  ? 52  ASP D CB  1 -0.278 0.314  -0.021 
ATOM   9719  C  CG  . ASP D 1 63  ? -31.823 33.984  -8.245  1    101.75 ? 52  ASP D CG  1 -0.292 0.311  -0.021 
ATOM   9720  O  OD1 . ASP D 1 63  ? -32.592 34.916  -7.912  1    101.55 ? 52  ASP D OD1 1 -0.299 0.32   -0.02  
ATOM   9721  O  OD2 . ASP D 1 63  ? -32.226 32.81   -8.399  1    103.02 ? 52  ASP D OD2 1 -0.295 0.301  -0.021 
ATOM   9722  N  N   . GLN D 1 64  ? -30.657 37.144  -8.971  1    97.02  ? 53  GLN D N   1 -0.281 0.34   -0.022 
ATOM   9723  C  CA  . GLN D 1 64  ? -31.283 38.448  -9.177  1    95.85  ? 53  GLN D CA  1 -0.287 0.352  -0.023 
ATOM   9724  C  C   . GLN D 1 64  ? -32.764 38.41   -8.851  1    95.74  ? 53  GLN D C   1 -0.3   0.352  -0.022 
ATOM   9725  O  O   . GLN D 1 64  ? -33.316 39.403  -8.36   1    97.4   ? 53  GLN D O   1 -0.305 0.361  -0.021 
ATOM   9726  C  CB  . GLN D 1 64  ? -31.089 38.946  -10.607 1    95.33  ? 53  GLN D CB  1 -0.285 0.357  -0.026 
ATOM   9727  C  CG  . GLN D 1 64  ? -29.674 39.316  -10.969 1    91.8   ? 53  GLN D CG  1 -0.272 0.36   -0.027 
ATOM   9728  C  CD  . GLN D 1 64  ? -29.13  40.487  -10.168 1    100.01 ? 53  GLN D CD  1 -0.267 0.371  -0.025 
ATOM   9729  O  OE1 . GLN D 1 64  ? -29.817 41.082  -9.314  1    95.37  ? 53  GLN D OE1 1 -0.273 0.376  -0.023 
ATOM   9730  N  NE2 . GLN D 1 64  ? -27.874 40.829  -10.443 1    99.76  ? 53  GLN D NE2 1 -0.255 0.374  -0.026 
ATOM   9731  N  N   . TYR D 1 65  ? -33.428 37.28   -9.111  1    92.27  ? 54  TYR D N   1 -0.306 0.342  -0.023 
ATOM   9732  C  CA  . TYR D 1 65  ? -34.858 37.198  -8.831  1    99.35  ? 54  TYR D CA  1 -0.319 0.341  -0.022 
ATOM   9733  C  C   . TYR D 1 65  ? -35.162 37.494  -7.363  1    98.76  ? 54  TYR D C   1 -0.322 0.344  -0.018 
ATOM   9734  O  O   . TYR D 1 65  ? -36.008 38.337  -7.053  1    95.47  ? 54  TYR D O   1 -0.33  0.351  -0.018 
ATOM   9735  C  CB  . TYR D 1 65  ? -35.42  35.827  -9.197  1    97.53  ? 54  TYR D CB  1 -0.325 0.328  -0.023 
ATOM   9736  C  CG  . TYR D 1 65  ? -36.723 35.539  -8.468  1    101.55 ? 54  TYR D CG  1 -0.337 0.326  -0.021 
ATOM   9737  C  CD1 . TYR D 1 65  ? -37.893 36.216  -8.799  1    100.72 ? 54  TYR D CD1 1 -0.347 0.332  -0.022 
ATOM   9738  C  CD2 . TYR D 1 65  ? -36.773 34.615  -7.431  1    108.04 ? 54  TYR D CD2 1 -0.337 0.317  -0.019 
ATOM   9739  C  CE1 . TYR D 1 65  ? -39.076 35.966  -8.139  1    100.32 ? 54  TYR D CE1 1 -0.358 0.33   -0.02  
ATOM   9740  C  CE2 . TYR D 1 65  ? -37.954 34.36   -6.757  1    107.89 ? 54  TYR D CE2 1 -0.348 0.315  -0.017 
ATOM   9741  C  CZ  . TYR D 1 65  ? -39.107 35.04   -7.123  1    107.66 ? 54  TYR D CZ  1 -0.358 0.321  -0.018 
ATOM   9742  O  OH  . TYR D 1 65  ? -40.3   34.803  -6.471  1    107.78 ? 54  TYR D OH  1 -0.369 0.319  -0.016 
ATOM   9743  N  N   . LEU D 1 66  ? -34.505 36.77   -6.449  1    98.67  ? 55  LEU D N   1 -0.316 0.337  -0.016 
ATOM   9744  C  CA  . LEU D 1 66  ? -34.733 36.97   -5.022  1    99.97  ? 55  LEU D CA  1 -0.318 0.339  -0.013 
ATOM   9745  C  C   . LEU D 1 66  ? -34.302 38.365  -4.594  1    97.86  ? 55  LEU D C   1 -0.314 0.352  -0.011 
ATOM   9746  O  O   . LEU D 1 66  ? -35.096 39.143  -4.045  1    88.72  ? 55  LEU D O   1 -0.322 0.359  -0.01  
ATOM   9747  C  CB  . LEU D 1 66  ? -33.977 35.914  -4.213  1    96.06  ? 55  LEU D CB  1 -0.311 0.329  -0.011 
ATOM   9748  C  CG  . LEU D 1 66  ? -34.571 34.509  -4.18   1    99.65  ? 55  LEU D CG  1 -0.317 0.316  -0.01  
ATOM   9749  C  CD1 . LEU D 1 66  ? -33.579 33.564  -3.538  1    100.75 ? 55  LEU D CD1 1 -0.308 0.308  -0.009 
ATOM   9750  C  CD2 . LEU D 1 66  ? -35.881 34.501  -3.408  1    100.2  ? 55  LEU D CD2 1 -0.329 0.316  -0.009 
ATOM   9751  N  N   . ARG D 1 67  ? -33.036 38.699  -4.861  1    96.93  ? 56  ARG D N   1 -0.303 0.355  -0.012 
ATOM   9752  C  CA  . ARG D 1 67  ? -32.481 39.985  -4.462  1    92.47  ? 56  ARG D CA  1 -0.298 0.366  -0.011 
ATOM   9753  C  C   . ARG D 1 67  ? -33.367 41.142  -4.906  1    95.18  ? 56  ARG D C   1 -0.306 0.377  -0.012 
ATOM   9754  O  O   . ARG D 1 67  ? -33.658 42.043  -4.121  1    97.69  ? 56  ARG D O   1 -0.308 0.385  -0.01  
ATOM   9755  C  CB  . ARG D 1 67  ? -31.069 40.124  -5.023  1    90.95  ? 56  ARG D CB  1 -0.285 0.368  -0.013 
ATOM   9756  C  CG  . ARG D 1 67  ? -30.573 41.533  -5.133  1    90.43  ? 56  ARG D CG  1 -0.28  0.381  -0.013 
ATOM   9757  C  CD  . ARG D 1 67  ? -29.529 41.561  -6.197  1    100.01 ? 56  ARG D CD  1 -0.271 0.381  -0.015 
ATOM   9758  N  NE  . ARG D 1 67  ? -29.252 42.911  -6.661  1    109.49 ? 56  ARG D NE  1 -0.268 0.393  -0.017 
ATOM   9759  C  CZ  . ARG D 1 67  ? -28.255 43.648  -6.196  1    110.52 ? 56  ARG D CZ  1 -0.259 0.4    -0.015 
ATOM   9760  N  NH1 . ARG D 1 67  ? -27.451 43.191  -5.251  1    107.82 ? 56  ARG D NH1 1 -0.252 0.396  -0.013 
ATOM   9761  N  NH2 . ARG D 1 67  ? -28.056 44.868  -6.693  1    106.5  ? 56  ARG D NH2 1 -0.257 0.411  -0.017 
ATOM   9762  N  N   . ILE D 1 68  ? -33.824 41.136  -6.159  1    101.84 ? 57  ILE D N   1 -0.31  0.377  -0.015 
ATOM   9763  C  CA  . ILE D 1 68  ? -34.67  42.241  -6.609  1    100.54 ? 57  ILE D CA  1 -0.318 0.387  -0.017 
ATOM   9764  C  C   . ILE D 1 68  ? -36.066 42.128  -6.004  1    94.56  ? 57  ILE D C   1 -0.331 0.386  -0.015 
ATOM   9765  O  O   . ILE D 1 68  ? -36.657 43.136  -5.599  1    91.32  ? 57  ILE D O   1 -0.336 0.395  -0.014 
ATOM   9766  C  CB  . ILE D 1 68  ? -34.702 42.322  -8.153  1    96.72  ? 57  ILE D CB  1 -0.318 0.388  -0.02  
ATOM   9767  C  CG1 . ILE D 1 68  ? -33.474 43.08   -8.647  1    92.73  ? 57  ILE D CG1 1 -0.307 0.395  -0.022 
ATOM   9768  C  CG2 . ILE D 1 68  ? -35.977 42.997  -8.654  1    87.48  ? 57  ILE D CG2 1 -0.33  0.394  -0.022 
ATOM   9769  C  CD1 . ILE D 1 68  ? -33.688 43.783  -9.93   1    94.94  ? 57  ILE D CD1 1 -0.309 0.401  -0.025 
ATOM   9770  N  N   . LYS D 1 69  ? -36.615 40.908  -5.934  1    96.83  ? 58  LYS D N   1 -0.336 0.375  -0.015 
ATOM   9771  C  CA  . LYS D 1 69  ? -37.938 40.708  -5.344  1    98.05  ? 58  LYS D CA  1 -0.348 0.373  -0.013 
ATOM   9772  C  C   . LYS D 1 69  ? -38.007 41.345  -3.971  1    101.4  ? 58  LYS D C   1 -0.348 0.379  -0.01  
ATOM   9773  O  O   . LYS D 1 69  ? -38.917 42.134  -3.681  1    100.79 ? 58  LYS D O   1 -0.357 0.386  -0.009 
ATOM   9774  C  CB  . LYS D 1 69  ? -38.259 39.213  -5.239  1    98.62  ? 58  LYS D CB  1 -0.351 0.359  -0.013 
ATOM   9775  C  CG  . LYS D 1 69  ? -39.588 38.866  -4.561  1    92.19  ? 58  LYS D CG  1 -0.363 0.356  -0.011 
ATOM   9776  C  CD  . LYS D 1 69  ? -39.655 37.36   -4.278  1    93.97  ? 58  LYS D CD  1 -0.363 0.342  -0.011 
ATOM   9777  C  CE  . LYS D 1 69  ? -40.961 36.935  -3.617  1    94.74  ? 58  LYS D CE  1 -0.375 0.338  -0.009 
ATOM   9778  N  NZ  . LYS D 1 69  ? -41.054 35.441  -3.486  1    94.16  ? 58  LYS D NZ  1 -0.376 0.325  -0.009 
ATOM   9779  N  N   . HIS D 1 70  ? -37.021 41.02   -3.125  1    102.42 ? 59  HIS D N   1 -0.339 0.376  -0.008 
ATOM   9780  C  CA  . HIS D 1 70  ? -36.912 41.581  -1.781  1    93.5   ? 59  HIS D CA  1 -0.338 0.381  -0.004 
ATOM   9781  C  C   . HIS D 1 70  ? -36.951 43.108  -1.791  1    95.29  ? 59  HIS D C   1 -0.339 0.395  -0.004 
ATOM   9782  O  O   . HIS D 1 70  ? -37.81  43.714  -1.138  1    100.7  ? 59  HIS D O   1 -0.346 0.401  -0.003 
ATOM   9783  C  CB  . HIS D 1 70  ? -35.628 41.074  -1.109  1    91.65  ? 59  HIS D CB  1 -0.326 0.376  -0.003 
ATOM   9784  C  CG  . HIS D 1 70  ? -35.61  39.593  -0.873  1    96.98  ? 59  HIS D CG  1 -0.326 0.363  -0.002 
ATOM   9785  N  ND1 . HIS D 1 70  ? -36.758 38.854  -0.671  1    97.78  ? 59  HIS D ND1 1 -0.337 0.356  -0.002 
ATOM   9786  C  CD2 . HIS D 1 70  ? -34.582 38.71   -0.825  1    94.68  ? 59  HIS D CD2 1 -0.317 0.355  -0.002 
ATOM   9787  C  CE1 . HIS D 1 70  ? -36.439 37.581  -0.503  1    97.63  ? 59  HIS D CE1 1 -0.334 0.344  -0.001 
ATOM   9788  N  NE2 . HIS D 1 70  ? -35.125 37.465  -0.593  1    99.14  ? 59  HIS D NE2 1 -0.322 0.343  -0.001 
ATOM   9789  N  N   . MET D 1 71  ? -36.025 43.753  -2.507  1    86.16  ? 60  MET D N   1 -0.33  0.401  -0.006 
ATOM   9790  C  CA  . MET D 1 71  ? -35.979 45.211  -2.451  1    89.04  ? 60  MET D CA  1 -0.33  0.414  -0.006 
ATOM   9791  C  C   . MET D 1 71  ? -37.283 45.831  -2.956  1    99.97  ? 60  MET D C   1 -0.342 0.42   -0.007 
ATOM   9792  O  O   . MET D 1 71  ? -37.743 46.842  -2.411  1    105.68 ? 60  MET D O   1 -0.346 0.429  -0.006 
ATOM   9793  C  CB  . MET D 1 71  ? -34.775 45.739  -3.224  1    85.58  ? 60  MET D CB  1 -0.319 0.419  -0.008 
ATOM   9794  C  CG  . MET D 1 71  ? -33.517 44.946  -2.995  1    90.3   ? 60  MET D CG  1 -0.307 0.412  -0.007 
ATOM   9795  S  SD  . MET D 1 71  ? -32.066 45.715  -3.717  1    93     ? 60  MET D SD  1 -0.294 0.419  -0.009 
ATOM   9796  C  CE  . MET D 1 71  ? -32.817 46.706  -5.027  1    94.43  ? 60  MET D CE  1 -0.301 0.428  -0.013 
ATOM   9797  N  N   . SER D 1 72  ? -37.93  45.209  -3.948  1    98.07  ? 61  SER D N   1 -0.348 0.414  -0.01  
ATOM   9798  C  CA  . SER D 1 72  ? -39.238 45.695  -4.391  1    102.07 ? 61  SER D CA  1 -0.36  0.419  -0.011 
ATOM   9799  C  C   . SER D 1 72  ? -40.25  45.669  -3.249  1    100.26 ? 61  SER D C   1 -0.369 0.419  -0.008 
ATOM   9800  O  O   . SER D 1 72  ? -40.968 46.647  -3.015  1    99.71  ? 61  SER D O   1 -0.375 0.427  -0.008 
ATOM   9801  C  CB  . SER D 1 72  ? -39.753 44.857  -5.564  1    99.76  ? 61  SER D CB  1 -0.364 0.411  -0.014 
ATOM   9802  O  OG  . SER D 1 72  ? -38.709 44.541  -6.466  1    102.12 ? 61  SER D OG  1 -0.355 0.408  -0.016 
ATOM   9803  N  N   . ALA D 1 73  ? -40.311 44.549  -2.52   1    100.2  ? 62  ALA D N   1 -0.369 0.408  -0.006 
ATOM   9804  C  CA  . ALA D 1 73  ? -41.301 44.374  -1.459  1    104.65 ? 62  ALA D CA  1 -0.378 0.407  -0.004 
ATOM   9805  C  C   . ALA D 1 73  ? -41.101 45.353  -0.302  1    107.09 ? 62  ALA D C   1 -0.377 0.416  -0.001 
ATOM   9806  O  O   . ALA D 1 73  ? -42.074 45.751  0.348   1    107.6  ? 62  ALA D O   1 -0.386 0.419  0.001  
ATOM   9807  C  CB  . ALA D 1 73  ? -41.259 42.933  -0.949  1    97.92  ? 62  ALA D CB  1 -0.378 0.393  -0.002 
ATOM   9808  N  N   . LEU D 1 74  ? -39.86  45.745  -0.018  1    101.86 ? 63  LEU D N   1 -0.365 0.419  -0.0   
ATOM   9809  C  CA  . LEU D 1 74  ? -39.644 46.817  0.945   1    95.82  ? 63  LEU D CA  1 -0.363 0.429  0.002  
ATOM   9810  C  C   . LEU D 1 74  ? -40.083 48.164  0.376   1    104.23 ? 63  LEU D C   1 -0.367 0.441  0.001  
ATOM   9811  O  O   . LEU D 1 74  ? -40.746 48.947  1.065   1    109.4  ? 63  LEU D O   1 -0.373 0.449  0.003  
ATOM   9812  C  CB  . LEU D 1 74  ? -38.176 46.854  1.365   1    99.24  ? 63  LEU D CB  1 -0.35  0.429  0.003  
ATOM   9813  C  CG  . LEU D 1 74  ? -37.796 48.003  2.294   1    93.36  ? 63  LEU D CG  1 -0.346 0.44   0.006  
ATOM   9814  C  CD1 . LEU D 1 74  ? -38.7   48.011  3.523   1    107.89 ? 63  LEU D CD1 1 -0.355 0.44   0.009  
ATOM   9815  C  CD2 . LEU D 1 74  ? -36.324 47.896  2.663   1    93.63  ? 63  LEU D CD2 1 -0.333 0.439  0.007  
ATOM   9816  N  N   . ILE D 1 75  ? -39.712 48.462  -0.879  1    103.1  ? 64  ILE D N   1 -0.364 0.444  -0.002 
ATOM   9817  C  CA  . ILE D 1 75  ? -40.136 49.72   -1.499  1    103.14 ? 64  ILE D CA  1 -0.368 0.456  -0.004 
ATOM   9818  C  C   . ILE D 1 75  ? -41.654 49.85   -1.47   1    107.73 ? 64  ILE D C   1 -0.382 0.457  -0.004 
ATOM   9819  O  O   . ILE D 1 75  ? -42.197 50.907  -1.123  1    107.75 ? 64  ILE D O   1 -0.387 0.467  -0.003 
ATOM   9820  C  CB  . ILE D 1 75  ? -39.592 49.833  -2.937  1    104.56 ? 64  ILE D CB  1 -0.363 0.457  -0.007 
ATOM   9821  C  CG1 . ILE D 1 75  ? -38.091 50.125  -2.927  1    102.01 ? 64  ILE D CG1 1 -0.349 0.459  -0.007 
ATOM   9822  C  CG2 . ILE D 1 75  ? -40.317 50.945  -3.686  1    106.07 ? 64  ILE D CG2 1 -0.369 0.467  -0.009 
ATOM   9823  C  CD1 . ILE D 1 75  ? -37.35  49.607  -4.112  1    94.26  ? 64  ILE D CD1 1 -0.342 0.455  -0.01  
ATOM   9824  N  N   . LYS D 1 76  ? -42.364 48.776  -1.828  1    112.63 ? 65  LYS D N   1 -0.388 0.447  -0.005 
ATOM   9825  C  CA  . LYS D 1 76  ? -43.817 48.864  -1.905  1    118.08 ? 65  LYS D CA  1 -0.402 0.448  -0.005 
ATOM   9826  C  C   . LYS D 1 76  ? -44.421 49.037  -0.53   1    114.57 ? 65  LYS D C   1 -0.407 0.449  -0.001 
ATOM   9827  O  O   . LYS D 1 76  ? -45.479 49.658  -0.392  1    121.38 ? 65  LYS D O   1 -0.417 0.455  -0.001 
ATOM   9828  C  CB  . LYS D 1 76  ? -44.408 47.628  -2.594  1    127.21 ? 65  LYS D CB  1 -0.407 0.436  -0.006 
ATOM   9829  C  CG  . LYS D 1 76  ? -45.926 47.716  -2.852  1    137.51 ? 65  LYS D CG  1 -0.421 0.437  -0.007 
ATOM   9830  C  CD  . LYS D 1 76  ? -46.353 49.123  -3.32   1    139.47 ? 65  LYS D CD  1 -0.425 0.45   -0.008 
ATOM   9831  C  CE  . LYS D 1 76  ? -47.772 49.157  -3.897  1    141.71 ? 65  LYS D CE  1 -0.438 0.45   -0.01  
ATOM   9832  N  NZ  . LYS D 1 76  ? -47.777 49.232  -5.403  1    138.14 ? 65  LYS D NZ  1 -0.438 0.451  -0.013 
ATOM   9833  N  N   . LYS D 1 77  ? -43.753 48.515  0.495   1    118.76 ? 66  LYS D N   1 -0.401 0.445  0.001  
ATOM   9834  C  CA  . LYS D 1 77  ? -44.253 48.642  1.858   1    110.45 ? 66  LYS D CA  1 -0.406 0.446  0.005  
ATOM   9835  C  C   . LYS D 1 77  ? -44.185 50.092  2.324   1    113.37 ? 66  LYS D C   1 -0.405 0.459  0.006  
ATOM   9836  O  O   . LYS D 1 77  ? -45.195 50.659  2.756   1    118.69 ? 66  LYS D O   1 -0.414 0.464  0.007  
ATOM   9837  C  CB  . LYS D 1 77  ? -43.455 47.722  2.785   1    107.31 ? 66  LYS D CB  1 -0.398 0.437  0.007  
ATOM   9838  C  CG  . LYS D 1 77  ? -44.063 47.529  4.15    1    124.3  ? 66  LYS D CG  1 -0.404 0.436  0.01   
ATOM   9839  C  CD  . LYS D 1 77  ? -44.496 46.085  4.38    1    123.51 ? 66  LYS D CD  1 -0.408 0.422  0.011  
ATOM   9840  C  CE  . LYS D 1 77  ? -45.509 46.023  5.51    1    118.77 ? 66  LYS D CE  1 -0.417 0.422  0.014  
ATOM   9841  N  NZ  . LYS D 1 77  ? -45.052 46.86   6.664   1    119.82 ? 66  LYS D NZ  1 -0.413 0.429  0.017  
ATOM   9842  N  N   . TYR D 1 78  ? -43.005 50.715  2.209   1    111.51 ? 67  TYR D N   1 -0.394 0.465  0.006  
ATOM   9843  C  CA  . TYR D 1 78  ? -42.769 52.063  2.717   1    113.39 ? 67  TYR D CA  1 -0.392 0.477  0.007  
ATOM   9844  C  C   . TYR D 1 78  ? -43.869 53.015  2.268   1    117.95 ? 67  TYR D C   1 -0.402 0.486  0.006  
ATOM   9845  O  O   . TYR D 1 78  ? -43.81  53.574  1.168   1    119.88 ? 67  TYR D O   1 -0.401 0.491  0.003  
ATOM   9846  C  CB  . TYR D 1 78  ? -41.394 52.585  2.279   1    107.12 ? 67  TYR D CB  1 -0.379 0.482  0.006  
ATOM   9847  C  CG  . TYR D 1 78  ? -40.892 53.76   3.106   1    115.81 ? 67  TYR D CG  1 -0.375 0.493  0.008  
ATOM   9848  C  CD1 . TYR D 1 78  ? -41.547 54.991  3.071   1    121.89 ? 67  TYR D CD1 1 -0.381 0.504  0.008  
ATOM   9849  C  CD2 . TYR D 1 78  ? -39.769 53.641  3.926   1    114.94 ? 67  TYR D CD2 1 -0.364 0.492  0.01   
ATOM   9850  C  CE1 . TYR D 1 78  ? -41.106 56.077  3.83    1    123.08 ? 67  TYR D CE1 1 -0.377 0.514  0.01   
ATOM   9851  C  CE2 . TYR D 1 78  ? -39.314 54.725  4.692   1    121.18 ? 67  TYR D CE2 1 -0.36  0.502  0.012  
ATOM   9852  C  CZ  . TYR D 1 78  ? -39.988 55.947  4.638   1    125.19 ? 67  TYR D CZ  1 -0.366 0.513  0.012  
ATOM   9853  O  OH  . TYR D 1 78  ? -39.554 57.035  5.385   1    121.86 ? 67  TYR D OH  1 -0.362 0.523  0.013  
ATOM   9854  N  N   . GLY D 1 79  ? -44.888 53.167  3.119   1    128.23 ? 68  GLY D N   1 -0.411 0.487  0.008  
ATOM   9855  C  CA  . GLY D 1 79  ? -45.958 54.14   2.974   1    137.69 ? 68  GLY D CA  1 -0.421 0.496  0.007  
ATOM   9856  C  C   . GLY D 1 79  ? -46.336 54.579  1.571   1    129.72 ? 68  GLY D C   1 -0.425 0.5    0.004  
ATOM   9857  O  O   . GLY D 1 79  ? -46.705 53.758  0.728   1    123.75 ? 68  GLY D O   1 -0.428 0.493  0.002  
ATOM   9858  N  N   . ASP D 1 80  ? -46.244 55.878  1.311   1    125.96 ? 69  ASP D N   1 -0.424 0.512  0.003  
ATOM   9859  C  CA  . ASP D 1 80  ? -46.74  56.462  0.075   1    128.35 ? 69  ASP D CA  1 -0.428 0.517  0.0    
ATOM   9860  C  C   . ASP D 1 80  ? -45.551 57.016  -0.707  1    130.97 ? 69  ASP D C   1 -0.417 0.523  -0.002 
ATOM   9861  O  O   . ASP D 1 80  ? -45.052 58.105  -0.414  1    133.61 ? 69  ASP D O   1 -0.413 0.532  -0.001 
ATOM   9862  C  CB  . ASP D 1 80  ? -47.79  57.529  0.374   1    137.31 ? 69  ASP D CB  1 -0.438 0.527  0.001  
ATOM   9863  C  CG  . ASP D 1 80  ? -49.212 57.045  0.087   1    144.21 ? 69  ASP D CG  1 -0.451 0.523  0.0    
ATOM   9864  O  OD1 . ASP D 1 80  ? -49.442 55.812  0.116   1    136.86 ? 69  ASP D OD1 1 -0.453 0.511  0.0    
ATOM   9865  O  OD2 . ASP D 1 80  ? -50.09  57.897  -0.194  1    149.45 ? 69  ASP D OD2 1 -0.459 0.531  -0.0   
ATOM   9866  N  N   . LEU D 1 81  ? -45.103 56.251  -1.692  1    127.58 ? 70  LEU D N   1 -0.413 0.515  -0.004 
ATOM   9867  C  CA  . LEU D 1 81  ? -44.034 56.615  -2.605  1    120.89 ? 70  LEU D CA  1 -0.404 0.519  -0.007 
ATOM   9868  C  C   . LEU D 1 81  ? -44.574 56.598  -4.026  1    123.9  ? 70  LEU D C   1 -0.408 0.519  -0.01  
ATOM   9869  O  O   . LEU D 1 81  ? -45.561 55.91   -4.32   1    124.25 ? 70  LEU D O   1 -0.418 0.512  -0.011 
ATOM   9870  C  CB  . LEU D 1 81  ? -42.855 55.636  -2.483  1    120.62 ? 70  LEU D CB  1 -0.393 0.51   -0.006 
ATOM   9871  C  CG  . LEU D 1 81  ? -42.329 55.304  -1.077  1    120    ? 70  LEU D CG  1 -0.388 0.507  -0.003 
ATOM   9872  C  CD1 . LEU D 1 81  ? -41.37  54.111  -1.079  1    109.84 ? 70  LEU D CD1 1 -0.379 0.496  -0.003 
ATOM   9873  C  CD2 . LEU D 1 81  ? -41.653 56.517  -0.475  1    114.94 ? 70  LEU D CD2 1 -0.382 0.518  -0.001 
ATOM   9874  N  N   . PRO D 1 82  ? -43.966 57.361  -4.938  1    119.8  ? 71  PRO D N   1 -0.403 0.526  -0.012 
ATOM   9875  C  CA  . PRO D 1 82  ? -44.306 57.225  -6.36   1    112.96 ? 71  PRO D CA  1 -0.406 0.524  -0.016 
ATOM   9876  C  C   . PRO D 1 82  ? -43.712 55.957  -6.964  1    110.38 ? 71  PRO D C   1 -0.401 0.513  -0.017 
ATOM   9877  O  O   . PRO D 1 82  ? -42.682 55.993  -7.653  1    101.55 ? 71  PRO D O   1 -0.391 0.513  -0.019 
ATOM   9878  C  CB  . PRO D 1 82  ? -43.701 58.488  -6.978  1    110.74 ? 71  PRO D CB  1 -0.4   0.536  -0.017 
ATOM   9879  C  CG  . PRO D 1 82  ? -42.551 58.808  -6.081  1    117    ? 71  PRO D CG  1 -0.39  0.539  -0.015 
ATOM   9880  C  CD  . PRO D 1 82  ? -42.981 58.426  -4.696  1    115.95 ? 71  PRO D CD  1 -0.394 0.535  -0.012 
ATOM   9881  N  N   . VAL D 1 83  ? -44.348 54.822  -6.682  1    114.27 ? 72  VAL D N   1 -0.406 0.502  -0.017 
ATOM   9882  C  CA  . VAL D 1 83  ? -43.874 53.522  -7.147  1    115.67 ? 72  VAL D CA  1 -0.402 0.49   -0.018 
ATOM   9883  C  C   . VAL D 1 83  ? -44.486 53.238  -8.513  1    108.35 ? 72  VAL D C   1 -0.408 0.488  -0.021 
ATOM   9884  O  O   . VAL D 1 83  ? -45.713 53.24   -8.668  1    104.76 ? 72  VAL D O   1 -0.419 0.488  -0.022 
ATOM   9885  C  CB  . VAL D 1 83  ? -44.21  52.404  -6.146  1    118.09 ? 72  VAL D CB  1 -0.405 0.48   -0.015 
ATOM   9886  C  CG1 . VAL D 1 83  ? -45.672 52.494  -5.678  1    122.69 ? 72  VAL D CG1 1 -0.419 0.481  -0.014 
ATOM   9887  C  CG2 . VAL D 1 83  ? -43.932 51.038  -6.781  1    112.57 ? 72  VAL D CG2 1 -0.403 0.468  -0.017 
ATOM   9888  N  N   . ILE D 1 84  ? -43.633 53.003  -9.508  1    110.02 ? 73  ILE D N   1 -0.4   0.486  -0.024 
ATOM   9889  C  CA  . ILE D 1 84  ? -44.078 52.707  -10.867 1    111.29 ? 73  ILE D CA  1 -0.404 0.483  -0.027 
ATOM   9890  C  C   . ILE D 1 84  ? -43.4   51.421  -11.321 1    105.2  ? 73  ILE D C   1 -0.398 0.471  -0.028 
ATOM   9891  O  O   . ILE D 1 84  ? -42.18  51.272  -11.184 1    106.49 ? 73  ILE D O   1 -0.387 0.47   -0.028 
ATOM   9892  C  CB  . ILE D 1 84  ? -43.793 53.876  -11.833 1    109.32 ? 73  ILE D CB  1 -0.401 0.494  -0.03  
ATOM   9893  C  CG1 . ILE D 1 84  ? -42.291 54.145  -11.97  1    109.17 ? 73  ILE D CG1 1 -0.388 0.496  -0.03  
ATOM   9894  C  CG2 . ILE D 1 84  ? -44.492 55.153  -11.339 1    109.91 ? 73  ILE D CG2 1 -0.408 0.505  -0.028 
ATOM   9895  C  CD1 . ILE D 1 84  ? -41.848 54.446  -13.399 1    110.14 ? 73  ILE D CD1 1 -0.384 0.499  -0.033 
ATOM   9896  N  N   . THR D 1 85  ? -44.193 50.475  -11.826 1    101.33 ? 74  THR D N   1 -0.405 0.463  -0.03  
ATOM   9897  C  CA  . THR D 1 85  ? -43.65  49.17   -12.205 1    110.15 ? 74  THR D CA  1 -0.4   0.451  -0.03  
ATOM   9898  C  C   . THR D 1 85  ? -43.286 49.055  -13.697 1    114.06 ? 74  THR D C   1 -0.397 0.45   -0.034 
ATOM   9899  O  O   . THR D 1 85  ? -42.912 50.043  -14.343 1    110.31 ? 74  THR D O   1 -0.393 0.459  -0.036 
ATOM   9900  C  CB  . THR D 1 85  ? -44.647 48.081  -11.801 1    107.75 ? 74  THR D CB  1 -0.409 0.441  -0.029 
ATOM   9901  O  OG1 . THR D 1 85  ? -45.883 48.286  -12.491 1    117.54 ? 74  THR D OG1 1 -0.42  0.442  -0.031 
ATOM   9902  C  CG2 . THR D 1 85  ? -44.932 48.166  -10.324 1    109.63 ? 74  THR D CG2 1 -0.412 0.441  -0.026 
ATOM   9903  N  N   . THR D 1 86  ? -43.339 47.846  -14.254 1    112.33 ? 75  THR D N   1 -0.397 0.438  -0.036 
ATOM   9904  C  CA  . THR D 1 86  ? -43.067 47.668  -15.676 1    111.33 ? 75  THR D CA  1 -0.395 0.437  -0.039 
ATOM   9905  C  C   . THR D 1 86  ? -44.175 46.859  -16.332 1    116.92 ? 75  THR D C   1 -0.405 0.429  -0.041 
ATOM   9906  O  O   . THR D 1 86  ? -43.914 46.069  -17.242 1    124.84 ? 75  THR D O   1 -0.402 0.422  -0.043 
ATOM   9907  C  CB  . THR D 1 86  ? -41.708 47.004  -15.914 1    106.82 ? 75  THR D CB  1 -0.382 0.431  -0.04  
ATOM   9908  O  OG1 . THR D 1 86  ? -41.514 45.928  -14.989 1    101.68 ? 75  THR D OG1 1 -0.38  0.421  -0.037 
ATOM   9909  C  CG2 . THR D 1 86  ? -40.58  48.004  -15.777 1    105.04 ? 75  THR D CG2 1 -0.372 0.44   -0.039 
ATOM   9910  N  N   . GLN D 1 87  ? -45.417 47.039  -15.876 1    116.43 ? 76  GLN D N   1 -0.416 0.431  -0.04  
ATOM   9911  C  CA  . GLN D 1 87  ? -46.564 46.331  -16.437 1    125.29 ? 76  GLN D CA  1 -0.427 0.425  -0.041 
ATOM   9912  C  C   . GLN D 1 87  ? -47.603 47.296  -16.989 1    131.17 ? 76  GLN D C   1 -0.436 0.433  -0.042 
ATOM   9913  O  O   . GLN D 1 87  ? -48.786 46.947  -17.087 1    132.19 ? 76  GLN D O   1 -0.447 0.43   -0.043 
ATOM   9914  C  CB  . GLN D 1 87  ? -47.201 45.419  -15.389 1    123.27 ? 76  GLN D CB  1 -0.433 0.416  -0.038 
ATOM   9915  C  CG  . GLN D 1 87  ? -47.711 46.184  -14.194 1    127.53 ? 76  GLN D CG  1 -0.437 0.423  -0.035 
ATOM   9916  C  CD  . GLN D 1 87  ? -49.23  46.24   -14.122 1    132.95 ? 76  GLN D CD  1 -0.451 0.424  -0.035 
ATOM   9917  O  OE1 . GLN D 1 87  ? -49.905 45.202  -14.132 1    129.26 ? 76  GLN D OE1 1 -0.457 0.414  -0.035 
ATOM   9918  N  NE2 . GLN D 1 87  ? -49.778 47.456  -14.038 1    130.03 ? 76  GLN D NE2 1 -0.456 0.435  -0.035 
ATOM   9919  N  N   . GLU D 1 88  ? -47.169 48.486  -17.399 1    132.31 ? 77  GLU D N   1 -0.432 0.444  -0.043 
ATOM   9920  C  CA  . GLU D 1 88  ? -48.085 49.578  -17.68  1    130.53 ? 77  GLU D CA  1 -0.441 0.454  -0.044 
ATOM   9921  C  C   . GLU D 1 88  ? -47.409 50.642  -18.541 1    130.4  ? 77  GLU D C   1 -0.434 0.464  -0.046 
ATOM   9922  O  O   . GLU D 1 88  ? -48.026 51.646  -18.905 1    135.37 ? 77  GLU D O   1 -0.44  0.473  -0.047 
ATOM   9923  C  CB  . GLU D 1 88  ? -48.529 50.201  -16.367 1    131.2  ? 77  GLU D CB  1 -0.445 0.46   -0.041 
ATOM   9924  C  CG  . GLU D 1 88  ? -47.442 51.131  -15.797 1    130.92 ? 77  GLU D CG  1 -0.435 0.469  -0.039 
ATOM   9925  C  CD  . GLU D 1 88  ? -46.216 50.394  -15.226 1    131.51 ? 77  GLU D CD  1 -0.424 0.462  -0.038 
ATOM   9926  O  OE1 . GLU D 1 88  ? -45.68  50.849  -14.181 1    131.58 ? 77  GLU D OE1 1 -0.419 0.466  -0.035 
ATOM   9927  O  OE2 . GLU D 1 88  ? -45.787 49.371  -15.814 1    130.25 ? 77  GLU D OE2 1 -0.42  0.452  -0.039 
ATOM   9928  N  N   . THR D 1 89  ? -46.125 50.437  -18.847 1    129.63 ? 78  THR D N   1 -0.423 0.462  -0.047 
ATOM   9929  C  CA  . THR D 1 89  ? -45.35  51.385  -19.642 1    130.22 ? 78  THR D CA  1 -0.416 0.471  -0.049 
ATOM   9930  C  C   . THR D 1 89  ? -45.93  51.618  -21.041 1    135.62 ? 78  THR D C   1 -0.421 0.473  -0.053 
ATOM   9931  O  O   . THR D 1 89  ? -45.546 52.596  -21.693 1    139.51 ? 78  THR D O   1 -0.417 0.482  -0.054 
ATOM   9932  C  CB  . THR D 1 89  ? -43.909 50.871  -19.697 1    127.18 ? 78  THR D CB  1 -0.402 0.466  -0.049 
ATOM   9933  O  OG1 . THR D 1 89  ? -43.389 50.787  -18.357 1    123.11 ? 78  THR D OG1 1 -0.398 0.465  -0.046 
ATOM   9934  C  CG2 . THR D 1 89  ? -43.021 51.779  -20.532 1    115.07 ? 78  THR D CG2 1 -0.394 0.475  -0.051 
ATOM   9935  N  N   . ARG D 1 90  ? -46.865 50.777  -21.495 1    132.87 ? 79  ARG D N   1 -0.429 0.465  -0.054 
ATOM   9936  C  CA  . ARG D 1 90  ? -47.529 50.877  -22.797 1    132.24 ? 79  ARG D CA  1 -0.436 0.466  -0.057 
ATOM   9937  C  C   . ARG D 1 90  ? -46.522 50.841  -23.952 1    132.62 ? 79  ARG D C   1 -0.426 0.466  -0.06  
ATOM   9938  O  O   . ARG D 1 90  ? -45.796 51.808  -24.224 1    130.15 ? 79  ARG D O   1 -0.42  0.475  -0.06  
ATOM   9939  C  CB  . ARG D 1 90  ? -48.467 52.111  -22.854 1    131.21 ? 79  ARG D CB  1 -0.444 0.478  -0.057 
ATOM   9940  C  CG  . ARG D 1 90  ? -47.895 53.502  -23.224 1    130.05 ? 79  ARG D CG  1 -0.439 0.49   -0.058 
ATOM   9941  C  CD  . ARG D 1 90  ? -48.774 54.237  -24.253 1    140.35 ? 79  ARG D CD  1 -0.447 0.497  -0.061 
ATOM   9942  N  NE  . ARG D 1 90  ? -48.824 53.565  -25.552 1    142.62 ? 79  ARG D NE  1 -0.447 0.491  -0.064 
ATOM   9943  C  CZ  . ARG D 1 90  ? -48.045 53.858  -26.588 1    135.95 ? 79  ARG D CZ  1 -0.44  0.494  -0.066 
ATOM   9944  N  NH1 . ARG D 1 90  ? -47.147 54.829  -26.528 1    135.61 ? 79  ARG D NH1 1 -0.432 0.502  -0.066 
ATOM   9945  N  NH2 . ARG D 1 90  ? -48.169 53.157  -27.713 1    135.91 ? 79  ARG D NH2 1 -0.441 0.487  -0.069 
ATOM   9946  N  N   . LEU D 1 91  ? -46.461 49.703  -24.637 1    129.69 ? 80  LEU D N   1 -0.426 0.455  -0.062 
ATOM   9947  C  CA  . LEU D 1 91  ? -45.49  49.579  -25.705 1    124.23 ? 80  LEU D CA  1 -0.417 0.454  -0.064 
ATOM   9948  C  C   . LEU D 1 91  ? -46.188 49.581  -27.065 1    124.15 ? 80  LEU D C   1 -0.423 0.454  -0.068 
ATOM   9949  O  O   . LEU D 1 91  ? -47.317 49.101  -27.198 1    121.47 ? 80  LEU D O   1 -0.434 0.45   -0.068 
ATOM   9950  C  CB  . LEU D 1 91  ? -44.661 48.297  -25.541 1    123.64 ? 80  LEU D CB  1 -0.409 0.443  -0.064 
ATOM   9951  C  CG  . LEU D 1 91  ? -43.128 48.422  -25.586 1    116.39 ? 80  LEU D CG  1 -0.395 0.444  -0.064 
ATOM   9952  C  CD1 . LEU D 1 91  ? -42.678 49.788  -25.112 1    120.48 ? 80  LEU D CD1 1 -0.391 0.456  -0.063 
ATOM   9953  C  CD2 . LEU D 1 91  ? -42.444 47.328  -24.763 1    109.14 ? 80  LEU D CD2 1 -0.389 0.434  -0.062 
ATOM   9954  N  N   . PRO D 1 92  ? -45.554 50.144  -28.091 1    126.99 ? 81  PRO D N   1 -0.417 0.46   -0.07  
ATOM   9955  C  CA  . PRO D 1 92  ? -46.157 50.113  -29.42  1    122.98 ? 81  PRO D CA  1 -0.423 0.459  -0.073 
ATOM   9956  C  C   . PRO D 1 92  ? -46.289 48.685  -29.933 1    123.25 ? 81  PRO D C   1 -0.424 0.446  -0.075 
ATOM   9957  O  O   . PRO D 1 92  ? -45.568 47.777  -29.512 1    120.72 ? 81  PRO D O   1 -0.418 0.438  -0.074 
ATOM   9958  C  CB  . PRO D 1 92  ? -45.176 50.929  -30.264 1    125.2  ? 81  PRO D CB  1 -0.414 0.467  -0.076 
ATOM   9959  C  CG  . PRO D 1 92  ? -43.872 50.82   -29.547 1    115.29 ? 81  PRO D CG  1 -0.402 0.466  -0.074 
ATOM   9960  C  CD  . PRO D 1 92  ? -44.258 50.843  -28.098 1    127.16 ? 81  PRO D CD  1 -0.406 0.466  -0.07  
ATOM   9961  N  N   . TYR D 1 93  ? -47.232 48.508  -30.874 1    126.48 ? 82  TYR D N   1 -0.433 0.445  -0.077 
ATOM   9962  C  CA  . TYR D 1 93  ? -47.605 47.179  -31.362 1    123.32 ? 82  TYR D CA  1 -0.436 0.432  -0.078 
ATOM   9963  C  C   . TYR D 1 93  ? -46.393 46.39   -31.847 1    119.5  ? 82  TYR D C   1 -0.425 0.425  -0.08  
ATOM   9964  O  O   . TYR D 1 93  ? -46.318 45.17   -31.653 1    113.73 ? 82  TYR D O   1 -0.424 0.414  -0.079 
ATOM   9965  C  CB  . TYR D 1 93  ? -48.663 47.302  -32.478 1    127.63 ? 82  TYR D CB  1 -0.446 0.433  -0.081 
ATOM   9966  C  CG  . TYR D 1 93  ? -48.174 47.759  -33.866 1    126.53 ? 82  TYR D CG  1 -0.441 0.438  -0.085 
ATOM   9967  C  CD1 . TYR D 1 93  ? -47.724 46.835  -34.809 1    125.41 ? 82  TYR D CD1 1 -0.437 0.429  -0.087 
ATOM   9968  C  CD2 . TYR D 1 93  ? -48.208 49.107  -34.242 1    126.81 ? 82  TYR D CD2 1 -0.442 0.45   -0.085 
ATOM   9969  C  CE1 . TYR D 1 93  ? -47.293 47.242  -36.081 1    134.93 ? 82  TYR D CE1 1 -0.433 0.433  -0.09  
ATOM   9970  C  CE2 . TYR D 1 93  ? -47.78  49.525  -35.517 1    128.24 ? 82  TYR D CE2 1 -0.438 0.454  -0.089 
ATOM   9971  C  CZ  . TYR D 1 93  ? -47.323 48.588  -36.43  1    135.15 ? 82  TYR D CZ  1 -0.434 0.445  -0.091 
ATOM   9972  O  OH  . TYR D 1 93  ? -46.894 48.985  -37.687 1    127.42 ? 82  TYR D OH  1 -0.43  0.449  -0.094 
ATOM   9973  N  N   . TYR D 1 94  ? -45.43  47.064  -32.471 1    119.57 ? 83  TYR D N   1 -0.416 0.431  -0.081 
ATOM   9974  C  CA  . TYR D 1 94  ? -44.326 46.336  -33.078 1    120.5  ? 83  TYR D CA  1 -0.406 0.425  -0.083 
ATOM   9975  C  C   . TYR D 1 94  ? -43.295 45.898  -32.042 1    116.74 ? 83  TYR D C   1 -0.397 0.421  -0.08  
ATOM   9976  O  O   . TYR D 1 94  ? -42.6   44.897  -32.249 1    118.44 ? 83  TYR D O   1 -0.39  0.411  -0.081 
ATOM   9977  C  CB  . TYR D 1 94  ? -43.687 47.188  -34.175 1    116.09 ? 83  TYR D CB  1 -0.4   0.432  -0.085 
ATOM   9978  C  CG  . TYR D 1 94  ? -43.256 48.546  -33.704 1    117.8  ? 83  TYR D CG  1 -0.396 0.445  -0.084 
ATOM   9979  C  CD1 . TYR D 1 94  ? -44.17  49.594  -33.588 1    118.28 ? 83  TYR D CD1 1 -0.405 0.454  -0.084 
ATOM   9980  C  CD2 . TYR D 1 94  ? -41.937 48.783  -33.366 1    116.41 ? 83  TYR D CD2 1 -0.384 0.447  -0.083 
ATOM   9981  C  CE1 . TYR D 1 94  ? -43.772 50.852  -33.154 1    115.41 ? 83  TYR D CE1 1 -0.401 0.466  -0.083 
ATOM   9982  C  CE2 . TYR D 1 94  ? -41.531 50.032  -32.915 1    120.08 ? 83  TYR D CE2 1 -0.381 0.459  -0.082 
ATOM   9983  C  CZ  . TYR D 1 94  ? -42.446 51.066  -32.813 1    118.99 ? 83  TYR D CZ  1 -0.389 0.468  -0.082 
ATOM   9984  O  OH  . TYR D 1 94  ? -42.013 52.301  -32.367 1    114.34 ? 83  TYR D OH  1 -0.385 0.479  -0.081 
ATOM   9985  N  N   . TRP D 1 95  ? -43.182 46.607  -30.921 1    117.95 ? 84  TRP D N   1 -0.396 0.427  -0.077 
ATOM   9986  C  CA  . TRP D 1 95  ? -42.334 46.098  -29.848 1    112.9  ? 84  TRP D CA  1 -0.388 0.422  -0.075 
ATOM   9987  C  C   . TRP D 1 95  ? -42.929 44.826  -29.246 1    111.62 ? 84  TRP D C   1 -0.393 0.411  -0.073 
ATOM   9988  O  O   . TRP D 1 95  ? -42.238 43.805  -29.136 1    107.32 ? 84  TRP D O   1 -0.387 0.401  -0.073 
ATOM   9989  C  CB  . TRP D 1 95  ? -42.1   47.182  -28.789 1    103.43 ? 84  TRP D CB  1 -0.386 0.432  -0.072 
ATOM   9990  C  CG  . TRP D 1 95  ? -40.766 47.85   -28.983 1    96.72  ? 84  TRP D CG  1 -0.374 0.439  -0.072 
ATOM   9991  C  CD1 . TRP D 1 95  ? -40.524 49.159  -29.329 1    95.99  ? 84  TRP D CD1 1 -0.371 0.45   -0.073 
ATOM   9992  C  CD2 . TRP D 1 95  ? -39.49  47.217  -28.89  1    87.45  ? 84  TRP D CD2 1 -0.362 0.433  -0.072 
ATOM   9993  N  NE1 . TRP D 1 95  ? -39.166 49.373  -29.441 1    91.18  ? 84  TRP D NE1 1 -0.359 0.452  -0.074 
ATOM   9994  C  CE2 . TRP D 1 95  ? -38.509 48.199  -29.177 1    89.04  ? 84  TRP D CE2 1 -0.353 0.442  -0.073 
ATOM   9995  C  CE3 . TRP D 1 95  ? -39.079 45.915  -28.592 1    84.82  ? 84  TRP D CE3 1 -0.358 0.421  -0.071 
ATOM   9996  C  CZ2 . TRP D 1 95  ? -37.141 47.915  -29.161 1    87.14  ? 84  TRP D CZ2 1 -0.34  0.439  -0.073 
ATOM   9997  C  CZ3 . TRP D 1 95  ? -37.723 45.632  -28.587 1    88.23  ? 84  TRP D CZ3 1 -0.346 0.418  -0.071 
ATOM   9998  C  CH2 . TRP D 1 95  ? -36.766 46.632  -28.862 1    84.83  ? 84  TRP D CH2 1 -0.337 0.427  -0.072 
ATOM   9999  N  N   . LEU D 1 96  ? -44.223 44.86   -28.887 1    110.93 ? 85  LEU D N   1 -0.405 0.411  -0.072 
ATOM   10000 C  CA  . LEU D 1 96  ? -44.927 43.635  -28.503 1    108.54 ? 85  LEU D CA  1 -0.412 0.4    -0.071 
ATOM   10001 C  C   . LEU D 1 96  ? -44.732 42.527  -29.528 1    114.63 ? 85  LEU D C   1 -0.41  0.39   -0.074 
ATOM   10002 O  O   . LEU D 1 96  ? -44.54  41.362  -29.157 1    112.78 ? 85  LEU D O   1 -0.408 0.379  -0.073 
ATOM   10003 C  CB  . LEU D 1 96  ? -46.422 43.895  -28.331 1    105.36 ? 85  LEU D CB  1 -0.425 0.402  -0.071 
ATOM   10004 C  CG  . LEU D 1 96  ? -46.899 44.568  -27.057 1    114.59 ? 85  LEU D CG  1 -0.43  0.408  -0.068 
ATOM   10005 C  CD1 . LEU D 1 96  ? -47.095 46.045  -27.33  1    110.51 ? 85  LEU D CD1 1 -0.432 0.422  -0.068 
ATOM   10006 C  CD2 . LEU D 1 96  ? -48.179 43.893  -26.553 1    114.27 ? 85  LEU D CD2 1 -0.442 0.402  -0.066 
ATOM   10007 N  N   . ASP D 1 97  ? -44.804 42.871  -30.825 1    117.72 ? 86  ASP D N   1 -0.411 0.393  -0.077 
ATOM   10008 C  CA  . ASP D 1 97  ? -44.673 41.874  -31.887 1    111.87 ? 86  ASP D CA  1 -0.409 0.384  -0.08  
ATOM   10009 C  C   . ASP D 1 97  ? -43.359 41.112  -31.772 1    110.97 ? 86  ASP D C   1 -0.397 0.377  -0.079 
ATOM   10010 O  O   . ASP D 1 97  ? -43.34  39.874  -31.734 1    104.13 ? 86  ASP D O   1 -0.397 0.365  -0.079 
ATOM   10011 C  CB  . ASP D 1 97  ? -44.757 42.55   -33.26  1    120.41 ? 86  ASP D CB  1 -0.41  0.39   -0.083 
ATOM   10012 C  CG  . ASP D 1 97  ? -46.184 42.848  -33.693 1    126.13 ? 86  ASP D CG  1 -0.423 0.393  -0.084 
ATOM   10013 O  OD1 . ASP D 1 97  ? -47.113 42.621  -32.867 1    121.62 ? 86  ASP D OD1 1 -0.432 0.391  -0.082 
ATOM   10014 O  OD2 . ASP D 1 97  ? -46.36  43.303  -34.86  1    114.76 ? 86  ASP D OD2 1 -0.425 0.397  -0.087 
ATOM   10015 N  N   . LEU D 1 98  ? -42.243 41.851  -31.741 1    113.77 ? 87  LEU D N   1 -0.387 0.384  -0.079 
ATOM   10016 C  CA  . LEU D 1 98  ? -40.924 41.236  -31.646 1    109.39 ? 87  LEU D CA  1 -0.375 0.378  -0.079 
ATOM   10017 C  C   . LEU D 1 98  ? -40.829 40.314  -30.443 1    110.88 ? 87  LEU D C   1 -0.374 0.369  -0.076 
ATOM   10018 O  O   . LEU D 1 98  ? -40.251 39.224  -30.537 1    107.64 ? 87  LEU D O   1 -0.369 0.359  -0.076 
ATOM   10019 C  CB  . LEU D 1 98  ? -39.846 42.313  -31.563 1    107.05 ? 87  LEU D CB  1 -0.365 0.388  -0.079 
ATOM   10020 C  CG  . LEU D 1 98  ? -38.466 41.731  -31.282 1    104.02 ? 87  LEU D CG  1 -0.353 0.382  -0.078 
ATOM   10021 C  CD1 . LEU D 1 98  ? -38.106 40.753  -32.395 1    109.78 ? 87  LEU D CD1 1 -0.349 0.373  -0.081 
ATOM   10022 C  CD2 . LEU D 1 98  ? -37.437 42.845  -31.167 1    103.21 ? 87  LEU D CD2 1 -0.343 0.393  -0.078 
ATOM   10023 N  N   . PHE D 1 99  ? -41.376 40.744  -29.296 1    114.58 ? 88  PHE D N   1 -0.379 0.373  -0.073 
ATOM   10024 C  CA  . PHE D 1 99  ? -41.447 39.892  -28.111 1    110.8  ? 88  PHE D CA  1 -0.38  0.366  -0.07  
ATOM   10025 C  C   . PHE D 1 99  ? -42.122 38.58   -28.482 1    111.15 ? 88  PHE D C   1 -0.386 0.354  -0.071 
ATOM   10026 O  O   . PHE D 1 99  ? -41.464 37.535  -28.502 1    112.3  ? 88  PHE D O   1 -0.38  0.344  -0.071 
ATOM   10027 C  CB  . PHE D 1 99  ? -42.209 40.564  -26.959 1    106.04 ? 88  PHE D CB  1 -0.387 0.372  -0.067 
ATOM   10028 C  CG  . PHE D 1 99  ? -41.532 41.784  -26.404 1    101.48 ? 88  PHE D CG  1 -0.381 0.383  -0.066 
ATOM   10029 C  CD1 . PHE D 1 99  ? -40.163 41.953  -26.529 1    97.11  ? 88  PHE D CD1 1 -0.368 0.384  -0.066 
ATOM   10030 C  CD2 . PHE D 1 99  ? -42.271 42.767  -25.763 1    101.43 ? 88  PHE D CD2 1 -0.387 0.392  -0.064 
ATOM   10031 C  CE1 . PHE D 1 99  ? -39.543 43.091  -26.016 1    100.54 ? 88  PHE D CE1 1 -0.362 0.395  -0.065 
ATOM   10032 C  CE2 . PHE D 1 99  ? -41.661 43.898  -25.249 1    102.08 ? 88  PHE D CE2 1 -0.382 0.402  -0.063 
ATOM   10033 C  CZ  . PHE D 1 99  ? -40.297 44.063  -25.373 1    97.81  ? 88  PHE D CZ  1 -0.369 0.404  -0.063 
ATOM   10034 N  N   . ALA D 1 100 ? -43.417 38.636  -28.829 1    109.24 ? 89  ALA D N   1 -0.398 0.354  -0.072 
ATOM   10035 C  CA  . ALA D 1 100 ? -44.18  37.42   -29.107 1    105.28 ? 89  ALA D CA  1 -0.405 0.343  -0.073 
ATOM   10036 C  C   . ALA D 1 100 ? -43.456 36.484  -30.061 1    108.89 ? 89  ALA D C   1 -0.398 0.334  -0.075 
ATOM   10037 O  O   . ALA D 1 100 ? -43.657 35.266  -29.999 1    100.79 ? 89  ALA D O   1 -0.4   0.323  -0.075 
ATOM   10038 C  CB  . ALA D 1 100 ? -45.552 37.775  -29.669 1    102.51 ? 89  ALA D CB  1 -0.417 0.346  -0.074 
ATOM   10039 N  N   . ALA D 1 101 ? -42.609 37.038  -30.939 1    111.95 ? 90  ALA D N   1 -0.39  0.339  -0.077 
ATOM   10040 C  CA  . ALA D 1 101 ? -41.792 36.228  -31.838 1    111.23 ? 90  ALA D CA  1 -0.383 0.332  -0.079 
ATOM   10041 C  C   . ALA D 1 101 ? -40.727 35.442  -31.076 1    109.71 ? 90  ALA D C   1 -0.373 0.325  -0.078 
ATOM   10042 O  O   . ALA D 1 101 ? -40.406 34.304  -31.44  1    109.08 ? 90  ALA D O   1 -0.37  0.314  -0.078 
ATOM   10043 C  CB  . ALA D 1 101 ? -41.148 37.12   -32.898 1    111.64 ? 90  ALA D CB  1 -0.377 0.34   -0.082 
ATOM   10044 N  N   . ILE D 1 102 ? -40.153 36.035  -30.028 1    110.62 ? 91  ILE D N   1 -0.368 0.33   -0.075 
ATOM   10045 C  CA  . ILE D 1 102 ? -39.2   35.304  -29.201 1    113.52 ? 91  ILE D CA  1 -0.359 0.324  -0.073 
ATOM   10046 C  C   . ILE D 1 102 ? -39.889 34.174  -28.438 1    114.12 ? 91  ILE D C   1 -0.366 0.313  -0.071 
ATOM   10047 O  O   . ILE D 1 102 ? -39.258 33.162  -28.112 1    113.06 ? 91  ILE D O   1 -0.36  0.304  -0.07  
ATOM   10048 C  CB  . ILE D 1 102 ? -38.491 36.307  -28.275 1    104.17 ? 91  ILE D CB  1 -0.353 0.333  -0.071 
ATOM   10049 C  CG1 . ILE D 1 102 ? -38.195 37.587  -29.069 1    105.81 ? 91  ILE D CG1 1 -0.35  0.344  -0.073 
ATOM   10050 C  CG2 . ILE D 1 102 ? -37.212 35.725  -27.733 1    101.1  ? 91  ILE D CG2 1 -0.341 0.327  -0.069 
ATOM   10051 C  CD1 . ILE D 1 102 ? -37.206 38.53   -28.433 1    101.96 ? 91  ILE D CD1 1 -0.341 0.353  -0.071 
ATOM   10052 N  N   . ASP D 1 103 ? -41.201 34.297  -28.23  1    115.3  ? 92  ASP D N   1 -0.378 0.314  -0.07  
ATOM   10053 C  CA  . ASP D 1 103 ? -41.966 33.322  -27.46  1    112.06 ? 92  ASP D CA  1 -0.385 0.305  -0.069 
ATOM   10054 C  C   . ASP D 1 103 ? -42.155 32.001  -28.212 1    111.18 ? 92  ASP D C   1 -0.386 0.293  -0.07  
ATOM   10055 O  O   . ASP D 1 103 ? -41.969 30.933  -27.623 1    115.66 ? 92  ASP D O   1 -0.385 0.283  -0.069 
ATOM   10056 C  CB  . ASP D 1 103 ? -43.313 33.938  -27.069 1    117.03 ? 92  ASP D CB  1 -0.397 0.311  -0.068 
ATOM   10057 C  CG  . ASP D 1 103 ? -43.168 35.116  -26.105 1    115.15 ? 92  ASP D CG  1 -0.396 0.322  -0.065 
ATOM   10058 O  OD1 . ASP D 1 103 ? -43.166 34.873  -24.88  1    129.57 ? 92  ASP D OD1 1 -0.396 0.32   -0.062 
ATOM   10059 O  OD2 . ASP D 1 103 ? -43.039 36.273  -26.547 1    121.55 ? 92  ASP D OD2 1 -0.394 0.332  -0.066 
ATOM   10060 N  N   . GLU D 1 104 ? -42.521 32.028  -29.505 1    119.61 ? 93  GLU D N   1 -0.39  0.294  -0.074 
ATOM   10061 C  CA  . GLU D 1 104 ? -42.692 30.742  -30.204 1    122.42 ? 93  GLU D CA  1 -0.391 0.282  -0.075 
ATOM   10062 C  C   . GLU D 1 104 ? -41.379 30      -30.43  1    120.1  ? 93  GLU D C   1 -0.379 0.275  -0.076 
ATOM   10063 O  O   . GLU D 1 104 ? -41.417 28.83   -30.83  1    114.95 ? 93  GLU D O   1 -0.38  0.264  -0.077 
ATOM   10064 C  CB  . GLU D 1 104 ? -43.352 30.864  -31.595 1    110.84 ? 93  GLU D CB  1 -0.397 0.283  -0.079 
ATOM   10065 C  CG  . GLU D 1 104 ? -44.524 31.815  -31.759 1    114.87 ? 93  GLU D CG  1 -0.408 0.292  -0.079 
ATOM   10066 C  CD  . GLU D 1 104 ? -44.027 33.199  -32.086 1    124.29 ? 93  GLU D CD  1 -0.403 0.304  -0.08  
ATOM   10067 O  OE1 . GLU D 1 104 ? -42.89  33.469  -31.635 1    119.25 ? 93  GLU D OE1 1 -0.393 0.307  -0.079 
ATOM   10068 O  OE2 . GLU D 1 104 ? -44.727 33.984  -32.79  1    120.86 ? 93  GLU D OE2 1 -0.41  0.311  -0.082 
ATOM   10069 N  N   . GLY D 1 105 ? -40.234 30.64   -30.192 1    120.84 ? 94  GLY D N   1 -0.369 0.281  -0.075 
ATOM   10070 C  CA  . GLY D 1 105 ? -38.964 30.069  -30.585 1    117.88 ? 94  GLY D CA  1 -0.357 0.276  -0.076 
ATOM   10071 C  C   . GLY D 1 105 ? -38.609 30.288  -32.034 1    117.9  ? 94  GLY D C   1 -0.354 0.278  -0.08  
ATOM   10072 O  O   . GLY D 1 105 ? -37.694 29.626  -32.539 1    121.45 ? 94  GLY D O   1 -0.345 0.271  -0.081 
ATOM   10073 N  N   . ASP D 1 106 ? -39.293 31.21   -32.716 1    113.72 ? 95  ASP D N   1 -0.36  0.286  -0.082 
ATOM   10074 C  CA  . ASP D 1 106 ? -39.115 31.403  -34.154 1    120.6  ? 95  ASP D CA  1 -0.358 0.288  -0.085 
ATOM   10075 C  C   . ASP D 1 106 ? -38     32.415  -34.395 1    118.25 ? 95  ASP D C   1 -0.348 0.297  -0.086 
ATOM   10076 O  O   . ASP D 1 106 ? -38.228 33.609  -34.601 1    115.46 ? 95  ASP D O   1 -0.35  0.308  -0.086 
ATOM   10077 C  CB  . ASP D 1 106 ? -40.419 31.841  -34.806 1    120.37 ? 95  ASP D CB  1 -0.37  0.292  -0.087 
ATOM   10078 C  CG  . ASP D 1 106 ? -40.485 31.444  -36.253 1    120.47 ? 95  ASP D CG  1 -0.371 0.288  -0.091 
ATOM   10079 O  OD1 . ASP D 1 106 ? -39.457 31.604  -36.948 1    120.96 ? 95  ASP D OD1 1 -0.362 0.29   -0.092 
ATOM   10080 O  OD2 . ASP D 1 106 ? -41.543 30.936  -36.683 1    124.03 ? 95  ASP D OD2 1 -0.381 0.284  -0.092 
ATOM   10081 N  N   . THR D 1 107 ? -36.771 31.903  -34.391 1    119.87 ? 96  THR D N   1 -0.337 0.292  -0.086 
ATOM   10082 C  CA  . THR D 1 107 ? -35.591 32.741  -34.606 1    120.13 ? 96  THR D CA  1 -0.326 0.3    -0.086 
ATOM   10083 C  C   . THR D 1 107 ? -35.661 33.579  -35.877 1    115.61 ? 96  THR D C   1 -0.327 0.308  -0.09  
ATOM   10084 O  O   . THR D 1 107 ? -35.415 34.793  -35.792 1    112.99 ? 96  THR D O   1 -0.325 0.319  -0.089 
ATOM   10085 C  CB  . THR D 1 107 ? -34.332 31.861  -34.597 1    121.82 ? 96  THR D CB  1 -0.315 0.292  -0.086 
ATOM   10086 O  OG1 . THR D 1 107 ? -34.405 30.931  -33.508 1    110.17 ? 96  THR D OG1 1 -0.315 0.283  -0.084 
ATOM   10087 C  CG2 . THR D 1 107 ? -33.077 32.718  -34.471 1    113.42 ? 96  THR D CG2 1 -0.303 0.3    -0.086 
ATOM   10088 N  N   . PRO D 1 108 ? -35.991 33.027  -37.061 1    122.7  ? 97  PRO D N   1 -0.33  0.303  -0.093 
ATOM   10089 C  CA  . PRO D 1 108 ? -36.028 33.881  -38.272 1    115.57 ? 97  PRO D CA  1 -0.33  0.31   -0.096 
ATOM   10090 C  C   . PRO D 1 108 ? -37.194 34.858  -38.306 1    112.21 ? 97  PRO D C   1 -0.341 0.319  -0.096 
ATOM   10091 O  O   . PRO D 1 108 ? -37.027 35.978  -38.806 1    112.56 ? 97  PRO D O   1 -0.339 0.33   -0.097 
ATOM   10092 C  CB  . PRO D 1 108 ? -36.122 32.869  -39.423 1    108.38 ? 97  PRO D CB  1 -0.331 0.301  -0.098 
ATOM   10093 C  CG  . PRO D 1 108 ? -35.785 31.55   -38.838 1    120.43 ? 97  PRO D CG  1 -0.328 0.289  -0.097 
ATOM   10094 C  CD  . PRO D 1 108 ? -36.226 31.612  -37.399 1    124.02 ? 97  PRO D CD  1 -0.332 0.29   -0.093 
ATOM   10095 N  N   . LYS D 1 109 ? -38.38  34.458  -37.829 1    112.97 ? 98  LYS D N   1 -0.352 0.316  -0.094 
ATOM   10096 C  CA  . LYS D 1 109 ? -39.48  35.409  -37.658 1    110.67 ? 98  LYS D CA  1 -0.362 0.324  -0.094 
ATOM   10097 C  C   . LYS D 1 109 ? -39.109 36.519  -36.682 1    114.87 ? 98  LYS D C   1 -0.358 0.335  -0.092 
ATOM   10098 O  O   . LYS D 1 109 ? -39.47  37.687  -36.884 1    109.73 ? 98  LYS D O   1 -0.362 0.345  -0.092 
ATOM   10099 C  CB  . LYS D 1 109 ? -40.734 34.687  -37.168 1    107.95 ? 98  LYS D CB  1 -0.373 0.318  -0.093 
ATOM   10100 C  CG  . LYS D 1 109 ? -41.819 35.607  -36.664 1    100.74 ? 98  LYS D CG  1 -0.383 0.326  -0.092 
ATOM   10101 C  CD  . LYS D 1 109 ? -42.764 34.819  -35.803 1    113.65 ? 98  LYS D CD  1 -0.392 0.319  -0.089 
ATOM   10102 C  CE  . LYS D 1 109 ? -43.938 34.299  -36.603 1    116.92 ? 98  LYS D CE  1 -0.403 0.314  -0.091 
ATOM   10103 N  NZ  . LYS D 1 109 ? -45.119 35.219  -36.496 1    106.81 ? 98  LYS D NZ  1 -0.413 0.323  -0.091 
ATOM   10104 N  N   . ALA D 1 110 ? -38.392 36.169  -35.603 1    115.61 ? 99  ALA D N   1 -0.352 0.331  -0.089 
ATOM   10105 C  CA  . ALA D 1 110 ? -37.944 37.171  -34.646 1    110.1  ? 99  ALA D CA  1 -0.348 0.341  -0.087 
ATOM   10106 C  C   . ALA D 1 110 ? -36.754 37.957  -35.182 1    111.69 ? 99  ALA D C   1 -0.337 0.348  -0.088 
ATOM   10107 O  O   . ALA D 1 110 ? -36.631 39.157  -34.911 1    114.8  ? 99  ALA D O   1 -0.336 0.359  -0.087 
ATOM   10108 C  CB  . ALA D 1 110 ? -37.61  36.509  -33.309 1    117.08 ? 99  ALA D CB  1 -0.345 0.335  -0.083 
ATOM   10109 N  N   . HIS D 1 111 ? -35.866 37.298  -35.935 1    111.21 ? 100 HIS D N   1 -0.329 0.342  -0.09  
ATOM   10110 C  CA  . HIS D 1 111 ? -34.818 38.024  -36.646 1    112.74 ? 100 HIS D CA  1 -0.319 0.348  -0.091 
ATOM   10111 C  C   . HIS D 1 111 ? -35.413 39.095  -37.55  1    111.91 ? 100 HIS D C   1 -0.325 0.358  -0.094 
ATOM   10112 O  O   . HIS D 1 111 ? -34.881 40.21   -37.645 1    110.34 ? 100 HIS D O   1 -0.32  0.368  -0.094 
ATOM   10113 C  CB  . HIS D 1 111 ? -33.965 37.052  -37.466 1    113.58 ? 100 HIS D CB  1 -0.311 0.34   -0.094 
ATOM   10114 C  CG  . HIS D 1 111 ? -32.884 37.712  -38.269 1    115.91 ? 100 HIS D CG  1 -0.301 0.346  -0.096 
ATOM   10115 N  ND1 . HIS D 1 111 ? -31.748 38.241  -37.695 1    111.95 ? 100 HIS D ND1 1 -0.291 0.35   -0.094 
ATOM   10116 C  CD2 . HIS D 1 111 ? -32.77  37.93   -39.603 1    122.58 ? 100 HIS D CD2 1 -0.3   0.348  -0.099 
ATOM   10117 C  CE1 . HIS D 1 111 ? -30.98  38.755  -38.638 1    117.1  ? 100 HIS D CE1 1 -0.284 0.355  -0.096 
ATOM   10118 N  NE2 . HIS D 1 111 ? -31.578 38.583  -39.804 1    125.72 ? 100 HIS D NE2 1 -0.289 0.354  -0.099 
ATOM   10119 N  N   . ALA D 1 112 ? -36.528 38.777  -38.215 1    114.27 ? 101 ALA D N   1 -0.335 0.355  -0.095 
ATOM   10120 C  CA  . ALA D 1 112 ? -37.101 39.682  -39.206 1    114.21 ? 101 ALA D CA  1 -0.34  0.364  -0.098 
ATOM   10121 C  C   . ALA D 1 112 ? -37.847 40.831  -38.542 1    111.77 ? 101 ALA D C   1 -0.347 0.374  -0.096 
ATOM   10122 O  O   . ALA D 1 112 ? -37.674 41.996  -38.92  1    107.04 ? 101 ALA D O   1 -0.345 0.385  -0.097 
ATOM   10123 C  CB  . ALA D 1 112 ? -38.033 38.914  -40.147 1    109.42 ? 101 ALA D CB  1 -0.349 0.357  -0.1   
ATOM   10124 N  N   . LEU D 1 113 ? -38.691 40.507  -37.554 1    113.37 ? 102 LEU D N   1 -0.355 0.371  -0.094 
ATOM   10125 C  CA  . LEU D 1 113 ? -39.427 41.527  -36.812 1    108.29 ? 102 LEU D CA  1 -0.361 0.381  -0.092 
ATOM   10126 C  C   . LEU D 1 113 ? -38.478 42.51   -36.134 1    104.46 ? 102 LEU D C   1 -0.353 0.39   -0.09  
ATOM   10127 O  O   . LEU D 1 113 ? -38.789 43.702  -36.002 1    95.31  ? 102 LEU D O   1 -0.355 0.4    -0.09  
ATOM   10128 C  CB  . LEU D 1 113 ? -40.331 40.838  -35.795 1    104.11 ? 102 LEU D CB  1 -0.37  0.374  -0.089 
ATOM   10129 C  CG  . LEU D 1 113 ? -41.691 40.401  -36.327 1    103.17 ? 102 LEU D CG  1 -0.382 0.37   -0.091 
ATOM   10130 C  CD1 . LEU D 1 113 ? -42.163 39.085  -35.715 1    101.1  ? 102 LEU D CD1 1 -0.386 0.358  -0.089 
ATOM   10131 C  CD2 . LEU D 1 113 ? -42.68  41.516  -36.025 1    112.25 ? 102 LEU D CD2 1 -0.391 0.38   -0.09  
ATOM   10132 N  N   . PHE D 1 114 ? -37.307 42.032  -35.724 1    105.96 ? 103 PHE D N   1 -0.342 0.385  -0.089 
ATOM   10133 C  CA  . PHE D 1 114 ? -36.315 42.925  -35.151 1    109.39 ? 103 PHE D CA  1 -0.333 0.393  -0.088 
ATOM   10134 C  C   . PHE D 1 114 ? -35.834 43.919  -36.199 1    109.59 ? 103 PHE D C   1 -0.328 0.402  -0.09  
ATOM   10135 O  O   . PHE D 1 114 ? -35.798 45.127  -35.951 1    112.19 ? 103 PHE D O   1 -0.328 0.414  -0.09  
ATOM   10136 C  CB  . PHE D 1 114 ? -35.167 42.103  -34.552 1    109.17 ? 103 PHE D CB  1 -0.322 0.386  -0.086 
ATOM   10137 C  CG  . PHE D 1 114 ? -33.946 42.907  -34.231 1    112.49 ? 103 PHE D CG  1 -0.311 0.393  -0.085 
ATOM   10138 C  CD1 . PHE D 1 114 ? -33.973 43.883  -33.241 1    114.14 ? 103 PHE D CD1 1 -0.311 0.402  -0.083 
ATOM   10139 C  CD2 . PHE D 1 114 ? -32.763 42.68   -34.921 1    113.46 ? 103 PHE D CD2 1 -0.3   0.391  -0.087 
ATOM   10140 C  CE1 . PHE D 1 114 ? -32.84  44.622  -32.957 1    118.93 ? 103 PHE D CE1 1 -0.301 0.409  -0.082 
ATOM   10141 C  CE2 . PHE D 1 114 ? -31.627 43.413  -34.649 1    113.07 ? 103 PHE D CE2 1 -0.29  0.398  -0.087 
ATOM   10142 C  CZ  . PHE D 1 114 ? -31.662 44.384  -33.672 1    121.07 ? 103 PHE D CZ  1 -0.29  0.407  -0.084 
ATOM   10143 N  N   . HIS D 1 115 ? -35.526 43.434  -37.407 1    116.3  ? 104 HIS D N   1 -0.326 0.398  -0.093 
ATOM   10144 C  CA  . HIS D 1 115 ? -35.168 44.322  -38.515 1    115.51 ? 104 HIS D CA  1 -0.322 0.406  -0.096 
ATOM   10145 C  C   . HIS D 1 115 ? -36.343 45.157  -39.016 1    112.89 ? 104 HIS D C   1 -0.333 0.414  -0.097 
ATOM   10146 O  O   . HIS D 1 115 ? -36.156 45.943  -39.953 1    116.9  ? 104 HIS D O   1 -0.331 0.421  -0.1   
ATOM   10147 C  CB  . HIS D 1 115 ? -34.573 43.508  -39.671 1    111.19 ? 104 HIS D CB  1 -0.317 0.399  -0.099 
ATOM   10148 C  CG  . HIS D 1 115 ? -33.23  42.92   -39.359 1    118.06 ? 104 HIS D CG  1 -0.305 0.393  -0.098 
ATOM   10149 N  ND1 . HIS D 1 115 ? -32.273 43.601  -38.634 1    117.4  ? 104 HIS D ND1 1 -0.296 0.4    -0.096 
ATOM   10150 C  CD2 . HIS D 1 115 ? -32.688 41.714  -39.655 1    118.76 ? 104 HIS D CD2 1 -0.3   0.382  -0.099 
ATOM   10151 C  CE1 . HIS D 1 115 ? -31.198 42.844  -38.506 1    113.83 ? 104 HIS D CE1 1 -0.286 0.393  -0.096 
ATOM   10152 N  NE2 . HIS D 1 115 ? -31.423 41.694  -39.115 1    113.68 ? 104 HIS D NE2 1 -0.288 0.382  -0.098 
ATOM   10153 N  N   . LEU D 1 116 ? -37.531 45.011  -38.416 1    112.26 ? 105 LEU D N   1 -0.344 0.412  -0.096 
ATOM   10154 C  CA  . LEU D 1 116 ? -38.727 45.77   -38.77  1    111.09 ? 105 LEU D CA  1 -0.355 0.419  -0.097 
ATOM   10155 C  C   . LEU D 1 116 ? -38.977 46.98   -37.875 1    112.36 ? 105 LEU D C   1 -0.357 0.431  -0.095 
ATOM   10156 O  O   . LEU D 1 116 ? -39.867 47.778  -38.196 1    111.52 ? 105 LEU D O   1 -0.365 0.438  -0.095 
ATOM   10157 C  CB  . LEU D 1 116 ? -39.977 44.873  -38.713 1    110.9  ? 105 LEU D CB  1 -0.366 0.411  -0.097 
ATOM   10158 C  CG  . LEU D 1 116 ? -40.501 44.207  -39.984 1    111.53 ? 105 LEU D CG  1 -0.371 0.405  -0.1   
ATOM   10159 C  CD1 . LEU D 1 116 ? -42.017 43.919  -39.894 1    101.26 ? 105 LEU D CD1 1 -0.385 0.402  -0.1   
ATOM   10160 C  CD2 . LEU D 1 116 ? -40.161 45.074  -41.176 1    110.63 ? 105 LEU D CD2 1 -0.368 0.413  -0.103 
ATOM   10161 N  N   . LEU D 1 117 ? -38.253 47.126  -36.761 1    113.11 ? 106 LEU D N   1 -0.351 0.432  -0.092 
ATOM   10162 C  CA  . LEU D 1 117 ? -38.549 48.21   -35.82  1    113.53 ? 106 LEU D CA  1 -0.353 0.442  -0.089 
ATOM   10163 C  C   . LEU D 1 117 ? -38.207 49.556  -36.447 1    113.46 ? 106 LEU D C   1 -0.35  0.454  -0.091 
ATOM   10164 O  O   . LEU D 1 117 ? -37.125 49.7    -37.038 1    112.41 ? 106 LEU D O   1 -0.34  0.455  -0.092 
ATOM   10165 C  CB  . LEU D 1 117 ? -37.768 48.045  -34.518 1    110.88 ? 106 LEU D CB  1 -0.346 0.44   -0.086 
ATOM   10166 C  CG  . LEU D 1 117 ? -37.536 46.666  -33.894 1    115.79 ? 106 LEU D CG  1 -0.344 0.428  -0.085 
ATOM   10167 C  CD1 . LEU D 1 117 ? -36.64  46.76   -32.637 1    111.28 ? 106 LEU D CD1 1 -0.336 0.429  -0.081 
ATOM   10168 C  CD2 . LEU D 1 117 ? -38.867 45.964  -33.586 1    116.47 ? 106 LEU D CD2 1 -0.356 0.421  -0.084 
ATOM   10169 N  N   . PRO D 1 118 ? -39.103 50.563  -36.353 1    110.52 ? 107 PRO D N   1 -0.358 0.463  -0.091 
ATOM   10170 C  CA  . PRO D 1 118 ? -38.772 51.904  -36.859 1    110.71 ? 107 PRO D CA  1 -0.355 0.476  -0.092 
ATOM   10171 C  C   . PRO D 1 118 ? -37.373 52.325  -36.455 1    112.04 ? 107 PRO D C   1 -0.342 0.48   -0.091 
ATOM   10172 O  O   . PRO D 1 118 ? -36.964 52.085  -35.323 1    119.7  ? 107 PRO D O   1 -0.339 0.477  -0.088 
ATOM   10173 C  CB  . PRO D 1 118 ? -39.848 52.786  -36.221 1    108.91 ? 107 PRO D CB  1 -0.365 0.484  -0.09  
ATOM   10174 C  CG  . PRO D 1 118 ? -41.047 51.861  -36.094 1    98.88  ? 107 PRO D CG  1 -0.376 0.475  -0.09  
ATOM   10175 C  CD  . PRO D 1 118 ? -40.509 50.461  -35.921 1    104.35 ? 107 PRO D CD  1 -0.371 0.462  -0.09  
ATOM   10176 N  N   . GLN D 1 119 ? -36.606 52.889  -37.383 1    121.17 ? 108 GLN D N   1 -0.335 0.485  -0.093 
ATOM   10177 C  CA  . GLN D 1 119 ? -35.253 53.321  -37.052 1    128.26 ? 108 GLN D CA  1 -0.323 0.489  -0.093 
ATOM   10178 C  C   . GLN D 1 119 ? -35.257 54.429  -36.008 1    132.27 ? 108 GLN D C   1 -0.323 0.499  -0.09  
ATOM   10179 O  O   . GLN D 1 119 ? -34.237 54.651  -35.335 1    127.04 ? 108 GLN D O   1 -0.314 0.501  -0.088 
ATOM   10180 C  CB  . GLN D 1 119 ? -34.535 53.784  -38.323 1    132.8  ? 108 GLN D CB  1 -0.316 0.493  -0.096 
ATOM   10181 C  CG  . GLN D 1 119 ? -33.643 52.721  -38.956 1    135.73 ? 108 GLN D CG  1 -0.308 0.483  -0.097 
ATOM   10182 C  CD  . GLN D 1 119 ? -32.365 52.468  -38.154 1    144.79 ? 108 GLN D CD  1 -0.297 0.481  -0.095 
ATOM   10183 O  OE1 . GLN D 1 119 ? -31.318 53.052  -38.451 1    148.96 ? 108 GLN D OE1 1 -0.287 0.486  -0.096 
ATOM   10184 N  NE2 . GLN D 1 119 ? -32.443 51.592  -37.139 1    131.5  ? 108 GLN D NE2 1 -0.297 0.473  -0.093 
ATOM   10185 N  N   . ASP D 1 120 ? -36.401 55.088  -35.835 1    132.75 ? 109 ASP D N   1 -0.334 0.505  -0.089 
ATOM   10186 C  CA  . ASP D 1 120 ? -36.557 56.267  -34.996 1    132.8  ? 109 ASP D CA  1 -0.335 0.516  -0.087 
ATOM   10187 C  C   . ASP D 1 120 ? -37.217 55.986  -33.646 1    124.21 ? 109 ASP D C   1 -0.341 0.513  -0.084 
ATOM   10188 O  O   . ASP D 1 120 ? -37.346 56.921  -32.848 1    120.28 ? 109 ASP D O   1 -0.342 0.522  -0.082 
ATOM   10189 C  CB  . ASP D 1 120 ? -37.384 57.312  -35.756 1    135.95 ? 109 ASP D CB  1 -0.343 0.525  -0.089 
ATOM   10190 C  CG  . ASP D 1 120 ? -38.777 56.794  -36.116 1    138.46 ? 109 ASP D CG  1 -0.355 0.52   -0.09  
ATOM   10191 O  OD1 . ASP D 1 120 ? -39.658 56.819  -35.218 1    143.58 ? 109 ASP D OD1 1 -0.363 0.521  -0.088 
ATOM   10192 O  OD2 . ASP D 1 120 ? -38.982 56.338  -37.272 1    129.43 ? 109 ASP D OD2 1 -0.357 0.516  -0.093 
ATOM   10193 N  N   . ASP D 1 121 ? -37.667 54.744  -33.39  1    122.54 ? 110 ASP D N   1 -0.345 0.502  -0.083 
ATOM   10194 C  CA  . ASP D 1 121 ? -38.233 54.375  -32.09  1    122.09 ? 110 ASP D CA  1 -0.35  0.498  -0.08  
ATOM   10195 C  C   . ASP D 1 121 ? -37.249 54.693  -30.973 1    115.1  ? 110 ASP D C   1 -0.341 0.501  -0.077 
ATOM   10196 O  O   . ASP D 1 121 ? -36.08  54.29   -31.022 1    110.79 ? 110 ASP D O   1 -0.331 0.498  -0.077 
ATOM   10197 C  CB  . ASP D 1 121 ? -38.605 52.883  -32.051 1    115.4  ? 110 ASP D CB  1 -0.354 0.485  -0.08  
ATOM   10198 C  CG  . ASP D 1 121 ? -38.86  52.358  -30.609 1    118.55 ? 110 ASP D CG  1 -0.356 0.48   -0.076 
ATOM   10199 O  OD1 . ASP D 1 121 ? -39.889 52.745  -29.985 1    116    ? 110 ASP D OD1 1 -0.366 0.483  -0.075 
ATOM   10200 O  OD2 . ASP D 1 121 ? -38.033 51.539  -30.116 1    108.77 ? 110 ASP D OD2 1 -0.349 0.472  -0.075 
ATOM   10201 N  N   . ILE D 1 122 ? -37.745 55.414  -29.96  1    114.67 ? 111 ILE D N   1 -0.346 0.508  -0.075 
ATOM   10202 C  CA  . ILE D 1 122 ? -36.867 55.999  -28.948 1    120.79 ? 111 ILE D CA  1 -0.338 0.513  -0.072 
ATOM   10203 C  C   . ILE D 1 122 ? -36.157 54.911  -28.137 1    115.94 ? 111 ILE D C   1 -0.331 0.503  -0.07  
ATOM   10204 O  O   . ILE D 1 122 ? -34.952 55.024  -27.856 1    115.43 ? 111 ILE D O   1 -0.32  0.504  -0.07  
ATOM   10205 C  CB  . ILE D 1 122 ? -37.651 56.987  -28.057 1    114.17 ? 111 ILE D CB  1 -0.345 0.522  -0.07  
ATOM   10206 C  CG1 . ILE D 1 122 ? -36.67  57.86   -27.279 1    117.91 ? 111 ILE D CG1 1 -0.336 0.53   -0.068 
ATOM   10207 C  CG2 . ILE D 1 122 ? -38.64  56.268  -27.145 1    95.43  ? 111 ILE D CG2 1 -0.354 0.516  -0.068 
ATOM   10208 C  CD1 . ILE D 1 122 ? -35.434 58.211  -28.102 1    120.08 ? 111 ILE D CD1 1 -0.325 0.533  -0.07  
ATOM   10209 N  N   . ILE D 1 123 ? -36.873 53.84   -27.774 1    108.15 ? 112 ILE D N   1 -0.338 0.493  -0.069 
ATOM   10210 C  CA  . ILE D 1 123 ? -36.23  52.659  -27.193 1    107.62 ? 112 ILE D CA  1 -0.332 0.483  -0.068 
ATOM   10211 C  C   . ILE D 1 123 ? -35.046 52.227  -28.055 1    110.92 ? 112 ILE D C   1 -0.321 0.479  -0.07  
ATOM   10212 O  O   . ILE D 1 123 ? -33.903 52.157  -27.589 1    108.96 ? 112 ILE D O   1 -0.311 0.478  -0.069 
ATOM   10213 C  CB  . ILE D 1 123 ? -37.248 51.517  -27.032 1    104.75 ? 112 ILE D CB  1 -0.341 0.472  -0.067 
ATOM   10214 C  CG1 . ILE D 1 123 ? -38.601 52.083  -26.602 1    107.03 ? 112 ILE D CG1 1 -0.354 0.477  -0.066 
ATOM   10215 C  CG2 . ILE D 1 123 ? -36.749 50.461  -26.052 1    96.45  ? 112 ILE D CG2 1 -0.337 0.462  -0.065 
ATOM   10216 C  CD1 . ILE D 1 123 ? -39.65  51.031  -26.364 1    100.97 ? 112 ILE D CD1 1 -0.363 0.468  -0.066 
ATOM   10217 N  N   . LEU D 1 124 ? -35.302 51.969  -29.346 1    115.22 ? 113 LEU D N   1 -0.324 0.476  -0.073 
ATOM   10218 C  CA  . LEU D 1 124 ? -34.261 51.41   -30.205 1    113.3  ? 113 LEU D CA  1 -0.314 0.471  -0.075 
ATOM   10219 C  C   . LEU D 1 124 ? -33.234 52.46   -30.615 1    114    ? 113 LEU D C   1 -0.305 0.481  -0.076 
ATOM   10220 O  O   . LEU D 1 124 ? -32.036 52.154  -30.714 1    112.59 ? 113 LEU D O   1 -0.294 0.478  -0.077 
ATOM   10221 C  CB  . LEU D 1 124 ? -34.886 50.762  -31.438 1    109.42 ? 113 LEU D CB  1 -0.32  0.465  -0.078 
ATOM   10222 C  CG  . LEU D 1 124 ? -33.96  50.377  -32.603 1    117.38 ? 113 LEU D CG  1 -0.311 0.462  -0.081 
ATOM   10223 C  CD1 . LEU D 1 124 ? -32.756 49.526  -32.154 1    113.24 ? 113 LEU D CD1 1 -0.3   0.454  -0.08  
ATOM   10224 C  CD2 . LEU D 1 124 ? -34.785 49.654  -33.666 1    116.02 ? 113 LEU D CD2 1 -0.319 0.455  -0.084 
ATOM   10225 N  N   . ARG D 1 125 ? -33.677 53.692  -30.886 1    112.35 ? 114 ARG D N   1 -0.309 0.492  -0.077 
ATOM   10226 C  CA  . ARG D 1 125 ? -32.726 54.747  -31.219 1    109.56 ? 114 ARG D CA  1 -0.3   0.502  -0.078 
ATOM   10227 C  C   . ARG D 1 125 ? -31.626 54.818  -30.171 1    113.96 ? 114 ARG D C   1 -0.29  0.502  -0.075 
ATOM   10228 O  O   . ARG D 1 125 ? -30.434 54.789  -30.5   1    107.73 ? 114 ARG D O   1 -0.279 0.502  -0.076 
ATOM   10229 C  CB  . ARG D 1 125 ? -33.434 56.093  -31.344 1    110.68 ? 114 ARG D CB  1 -0.306 0.514  -0.078 
ATOM   10230 C  CG  . ARG D 1 125 ? -32.472 57.232  -31.626 1    110.03 ? 114 ARG D CG  1 -0.298 0.524  -0.079 
ATOM   10231 C  CD  . ARG D 1 125 ? -33.234 58.477  -31.998 1    126.38 ? 114 ARG D CD  1 -0.305 0.536  -0.08  
ATOM   10232 N  NE  . ARG D 1 125 ? -33.734 59.211  -30.84  1    131.52 ? 114 ARG D NE  1 -0.309 0.543  -0.077 
ATOM   10233 C  CZ  . ARG D 1 125 ? -34.752 60.062  -30.887 1    134.28 ? 114 ARG D CZ  1 -0.318 0.55   -0.077 
ATOM   10234 N  NH1 . ARG D 1 125 ? -35.47  60.225  -31.993 1    139.5  ? 114 ARG D NH1 1 -0.325 0.552  -0.08  
ATOM   10235 N  NH2 . ARG D 1 125 ? -35.061 60.768  -29.803 1    127.29 ? 114 ARG D NH2 1 -0.321 0.557  -0.074 
ATOM   10236 N  N   . ALA D 1 126 ? -32.015 54.863  -28.891 1    116.06 ? 115 ALA D N   1 -0.293 0.503  -0.072 
ATOM   10237 C  CA  . ALA D 1 126 ? -31.026 54.867  -27.816 1    116.24 ? 115 ALA D CA  1 -0.284 0.503  -0.069 
ATOM   10238 C  C   . ALA D 1 126 ? -30.324 53.518  -27.709 1    112.18 ? 115 ALA D C   1 -0.278 0.49   -0.069 
ATOM   10239 O  O   . ALA D 1 126 ? -29.101 53.455  -27.513 1    109.43 ? 115 ALA D O   1 -0.267 0.49   -0.069 
ATOM   10240 C  CB  . ALA D 1 126 ? -31.694 55.238  -26.488 1    111.08 ? 115 ALA D CB  1 -0.29  0.506  -0.066 
ATOM   10241 N  N   . LEU D 1 127 ? -31.085 52.429  -27.832 1    108.5  ? 116 LEU D N   1 -0.285 0.48   -0.069 
ATOM   10242 C  CA  . LEU D 1 127 ? -30.511 51.091  -27.738 1    108.88 ? 116 LEU D CA  1 -0.28  0.468  -0.069 
ATOM   10243 C  C   . LEU D 1 127 ? -29.321 50.938  -28.677 1    116.16 ? 116 LEU D C   1 -0.269 0.467  -0.072 
ATOM   10244 O  O   . LEU D 1 127 ? -28.221 50.552  -28.256 1    108.83 ? 116 LEU D O   1 -0.259 0.463  -0.071 
ATOM   10245 C  CB  . LEU D 1 127 ? -31.594 50.059  -28.052 1    111.53 ? 116 LEU D CB  1 -0.29  0.459  -0.07  
ATOM   10246 C  CG  . LEU D 1 127 ? -31.327 48.59   -27.745 1    116.45 ? 116 LEU D CG  1 -0.287 0.445  -0.069 
ATOM   10247 C  CD1 . LEU D 1 127 ? -30.426 48.44   -26.524 1    106.57 ? 116 LEU D CD1 1 -0.279 0.444  -0.066 
ATOM   10248 C  CD2 . LEU D 1 127 ? -32.665 47.895  -27.525 1    109.43 ? 116 LEU D CD2 1 -0.299 0.439  -0.069 
ATOM   10249 N  N   . ARG D 1 128 ? -29.526 51.289  -29.959 1    124.19 ? 117 ARG D N   1 -0.271 0.47   -0.075 
ATOM   10250 C  CA  . ARG D 1 128 ? -28.51  51.12   -30.999 1    119.11 ? 117 ARG D CA  1 -0.261 0.468  -0.077 
ATOM   10251 C  C   . ARG D 1 128 ? -27.348 52.097  -30.848 1    118.82 ? 117 ARG D C   1 -0.251 0.477  -0.077 
ATOM   10252 O  O   . ARG D 1 128 ? -26.226 51.793  -31.277 1    113.95 ? 117 ARG D O   1 -0.24  0.475  -0.078 
ATOM   10253 C  CB  . ARG D 1 128 ? -29.152 51.274  -32.375 1    109.86 ? 117 ARG D CB  1 -0.267 0.47   -0.081 
ATOM   10254 C  CG  . ARG D 1 128 ? -29.322 49.96   -33.108 1    116.41 ? 117 ARG D CG  1 -0.269 0.458  -0.083 
ATOM   10255 C  CD  . ARG D 1 128 ? -27.975 49.237  -33.251 1    122.49 ? 117 ARG D CD  1 -0.256 0.451  -0.083 
ATOM   10256 N  NE  . ARG D 1 128 ? -27.03  49.933  -34.122 1    125.58 ? 117 ARG D NE  1 -0.248 0.458  -0.085 
ATOM   10257 C  CZ  . ARG D 1 128 ? -25.725 50.03   -33.893 1    126.81 ? 117 ARG D CZ  1 -0.236 0.458  -0.085 
ATOM   10258 N  NH1 . ARG D 1 128 ? -25.168 49.503  -32.816 1    127.77 ? 117 ARG D NH1 1 -0.231 0.454  -0.082 
ATOM   10259 N  NH2 . ARG D 1 128 ? -24.962 50.695  -34.756 1    127.36 ? 117 ARG D NH2 1 -0.229 0.465  -0.087 
ATOM   10260 N  N   . ALA D 1 129 ? -27.586 53.264  -30.249 1    120.4  ? 118 ALA D N   1 -0.253 0.488  -0.076 
ATOM   10261 C  CA  . ALA D 1 129 ? -26.495 54.195  -30.002 1    120.07 ? 118 ALA D CA  1 -0.243 0.497  -0.075 
ATOM   10262 C  C   . ALA D 1 129 ? -25.509 53.693  -28.948 1    120.29 ? 118 ALA D C   1 -0.234 0.492  -0.072 
ATOM   10263 O  O   . ALA D 1 129 ? -24.452 54.311  -28.776 1    125.01 ? 118 ALA D O   1 -0.224 0.498  -0.072 
ATOM   10264 C  CB  . ALA D 1 129 ? -27.058 55.558  -29.588 1    116.46 ? 118 ALA D CB  1 -0.248 0.509  -0.074 
ATOM   10265 N  N   . VAL D 1 130 ? -25.805 52.584  -28.26  1    113.4  ? 119 VAL D N   1 -0.236 0.482  -0.071 
ATOM   10266 C  CA  . VAL D 1 130 ? -24.97  52.09   -27.175 1    113.34 ? 119 VAL D CA  1 -0.229 0.477  -0.068 
ATOM   10267 C  C   . VAL D 1 130 ? -24.377 50.719  -27.48  1    112.33 ? 119 VAL D C   1 -0.223 0.465  -0.069 
ATOM   10268 O  O   . VAL D 1 130 ? -23.191 50.481  -27.209 1    107.64 ? 119 VAL D O   1 -0.213 0.463  -0.068 
ATOM   10269 C  CB  . VAL D 1 130 ? -25.76  52.068  -25.846 1    113.91 ? 119 VAL D CB  1 -0.236 0.477  -0.065 
ATOM   10270 C  CG1 . VAL D 1 130 ? -25.114 51.136  -24.824 1    107.82 ? 119 VAL D CG1 1 -0.23  0.469  -0.062 
ATOM   10271 C  CG2 . VAL D 1 130 ? -25.867 53.483  -25.303 1    110.46 ? 119 VAL D CG2 1 -0.237 0.49   -0.063 
ATOM   10272 N  N   . HIS D 1 131 ? -25.172 49.807  -28.059 1    114.56 ? 120 HIS D N   1 -0.231 0.456  -0.07  
ATOM   10273 C  CA  . HIS D 1 131 ? -24.74  48.444  -28.358 1    119.37 ? 120 HIS D CA  1 -0.227 0.444  -0.071 
ATOM   10274 C  C   . HIS D 1 131 ? -24.832 48.131  -29.851 1    122.94 ? 120 HIS D C   1 -0.228 0.441  -0.075 
ATOM   10275 O  O   . HIS D 1 131 ? -25.669 48.683  -30.58  1    120.76 ? 120 HIS D O   1 -0.235 0.446  -0.076 
ATOM   10276 C  CB  . HIS D 1 131 ? -25.56  47.416  -27.549 1    119.06 ? 120 HIS D CB  1 -0.234 0.435  -0.069 
ATOM   10277 C  CG  . HIS D 1 131 ? -25.367 47.544  -26.075 1    116.7  ? 120 HIS D CG  1 -0.232 0.436  -0.065 
ATOM   10278 N  ND1 . HIS D 1 131 ? -24.153 47.301  -25.462 1    114.46 ? 120 HIS D ND1 1 -0.221 0.433  -0.064 
ATOM   10279 C  CD2 . HIS D 1 131 ? -26.212 47.94   -25.096 1    110.47 ? 120 HIS D CD2 1 -0.24  0.439  -0.063 
ATOM   10280 C  CE1 . HIS D 1 131 ? -24.267 47.525  -24.167 1    112.94 ? 120 HIS D CE1 1 -0.222 0.436  -0.06  
ATOM   10281 N  NE2 . HIS D 1 131 ? -25.505 47.916  -23.917 1    113.19 ? 120 HIS D NE2 1 -0.234 0.439  -0.06  
ATOM   10282 N  N   . SER D 1 132 ? -23.963 47.22   -30.296 1    125.45 ? 121 SER D N   1 -0.22  0.433  -0.076 
ATOM   10283 C  CA  . SER D 1 132 ? -23.865 46.89   -31.714 1    122.57 ? 121 SER D CA  1 -0.219 0.43   -0.079 
ATOM   10284 C  C   . SER D 1 132 ? -24.923 45.868  -32.106 1    121.17 ? 121 SER D C   1 -0.228 0.42   -0.08  
ATOM   10285 O  O   . SER D 1 132 ? -25.044 44.804  -31.487 1    117.95 ? 121 SER D O   1 -0.23  0.411  -0.079 
ATOM   10286 C  CB  . SER D 1 132 ? -22.459 46.38   -32.059 1    120.96 ? 121 SER D CB  1 -0.206 0.425  -0.08  
ATOM   10287 O  OG  . SER D 1 132 ? -22.228 45.044  -31.632 1    113.63 ? 121 SER D OG  1 -0.204 0.413  -0.079 
ATOM   10288 N  N   . GLU D 1 133 ? -25.681 46.204  -33.15  1    129.97 ? 122 GLU D N   1 -0.235 0.423  -0.083 
ATOM   10289 C  CA  . GLU D 1 133 ? -26.712 45.38   -33.794 1    128.72 ? 122 GLU D CA  1 -0.245 0.416  -0.084 
ATOM   10290 C  C   . GLU D 1 133 ? -26.461 43.874  -33.783 1    124.64 ? 122 GLU D C   1 -0.242 0.402  -0.084 
ATOM   10291 O  O   . GLU D 1 133 ? -27.406 43.097  -33.947 1    122.24 ? 122 GLU D O   1 -0.251 0.395  -0.085 
ATOM   10292 C  CB  . GLU D 1 133 ? -26.915 45.853  -35.244 1    120.1  ? 122 GLU D CB  1 -0.247 0.42   -0.088 
ATOM   10293 C  CG  . GLU D 1 133 ? -25.69  45.699  -36.177 1    134.78 ? 122 GLU D CG  1 -0.235 0.419  -0.09  
ATOM   10294 C  CD  . GLU D 1 133 ? -24.416 46.377  -35.652 1    134.38 ? 122 GLU D CD  1 -0.224 0.425  -0.089 
ATOM   10295 O  OE1 . GLU D 1 133 ? -24.533 47.464  -35.038 1    132.92 ? 122 GLU D OE1 1 -0.225 0.435  -0.087 
ATOM   10296 O  OE2 . GLU D 1 133 ? -23.307 45.81   -35.831 1    131.89 ? 122 GLU D OE2 1 -0.214 0.42   -0.089 
ATOM   10297 N  N   . ASP D 1 134 ? -25.207 43.444  -33.607 1    125.19 ? 123 ASP D N   1 -0.231 0.398  -0.084 
ATOM   10298 C  CA  . ASP D 1 134 ? -24.941 42.022  -33.394 1    122.25 ? 123 ASP D CA  1 -0.229 0.385  -0.083 
ATOM   10299 C  C   . ASP D 1 134 ? -25.226 41.607  -31.957 1    117.87 ? 123 ASP D C   1 -0.231 0.381  -0.08  
ATOM   10300 O  O   . ASP D 1 134 ? -25.845 40.558  -31.735 1    113.57 ? 123 ASP D O   1 -0.237 0.372  -0.079 
ATOM   10301 C  CB  . ASP D 1 134 ? -23.501 41.68   -33.77  1    125.36 ? 123 ASP D CB  1 -0.215 0.382  -0.084 
ATOM   10302 C  CG  . ASP D 1 134 ? -23.269 41.722  -35.273 1    134.9  ? 123 ASP D CG  1 -0.213 0.382  -0.088 
ATOM   10303 O  OD1 . ASP D 1 134 ? -22.95  42.817  -35.794 1    134.85 ? 123 ASP D OD1 1 -0.21  0.392  -0.089 
ATOM   10304 O  OD2 . ASP D 1 134 ? -23.42  40.664  -35.929 1    134.3  ? 123 ASP D OD2 1 -0.215 0.373  -0.09  
ATOM   10305 N  N   . TYR D 1 135 ? -24.779 42.401  -30.972 1    120.92 ? 124 TYR D N   1 -0.227 0.389  -0.077 
ATOM   10306 C  CA  . TYR D 1 135 ? -25.105 42.095  -29.579 1    112.12 ? 124 TYR D CA  1 -0.23  0.386  -0.074 
ATOM   10307 C  C   . TYR D 1 135 ? -26.607 41.92   -29.403 1    107.28 ? 124 TYR D C   1 -0.244 0.384  -0.073 
ATOM   10308 O  O   . TYR D 1 135 ? -27.066 40.905  -28.866 1    101.76 ? 124 TYR D O   1 -0.248 0.375  -0.072 
ATOM   10309 C  CB  . TYR D 1 135 ? -24.591 43.188  -28.632 1    120.37 ? 124 TYR D CB  1 -0.225 0.396  -0.071 
ATOM   10310 C  CG  . TYR D 1 135 ? -24.345 42.63   -27.24  1    119.04 ? 124 TYR D CG  1 -0.223 0.391  -0.068 
ATOM   10311 C  CD1 . TYR D 1 135 ? -25.395 42.397  -26.357 1    112.16 ? 124 TYR D CD1 1 -0.233 0.389  -0.066 
ATOM   10312 C  CD2 . TYR D 1 135 ? -23.071 42.288  -26.839 1    118.13 ? 124 TYR D CD2 1 -0.211 0.388  -0.067 
ATOM   10313 C  CE1 . TYR D 1 135 ? -25.179 41.852  -25.114 1    116.58 ? 124 TYR D CE1 1 -0.231 0.384  -0.063 
ATOM   10314 C  CE2 . TYR D 1 135 ? -22.834 41.735  -25.617 1    122.73 ? 124 TYR D CE2 1 -0.209 0.382  -0.064 
ATOM   10315 C  CZ  . TYR D 1 135 ? -23.885 41.521  -24.739 1    129.28 ? 124 TYR D CZ  1 -0.219 0.381  -0.062 
ATOM   10316 O  OH  . TYR D 1 135 ? -23.643 40.975  -23.488 1    127.86 ? 124 TYR D OH  1 -0.217 0.376  -0.059 
ATOM   10317 N  N   . LEU D 1 136 ? -27.385 42.905  -29.873 1    105.87 ? 125 LEU D N   1 -0.251 0.393  -0.075 
ATOM   10318 C  CA  . LEU D 1 136 ? -28.84  42.856  -29.773 1    98.47  ? 125 LEU D CA  1 -0.264 0.393  -0.074 
ATOM   10319 C  C   . LEU D 1 136 ? -29.39  41.551  -30.33  1    106.29 ? 125 LEU D C   1 -0.269 0.381  -0.076 
ATOM   10320 O  O   . LEU D 1 136 ? -30.17  40.861  -29.663 1    99.92  ? 125 LEU D O   1 -0.276 0.374  -0.074 
ATOM   10321 C  CB  . LEU D 1 136 ? -29.466 44.052  -30.495 1    99.59  ? 125 LEU D CB  1 -0.27  0.404  -0.076 
ATOM   10322 C  CG  . LEU D 1 136 ? -29.177 45.465  -29.99  1    112.83 ? 125 LEU D CG  1 -0.267 0.417  -0.075 
ATOM   10323 C  CD1 . LEU D 1 136 ? -27.764 45.945  -30.38  1    114.45 ? 125 LEU D CD1 1 -0.254 0.421  -0.076 
ATOM   10324 C  CD2 . LEU D 1 136 ? -30.29  46.43   -30.452 1    107.12 ? 125 LEU D CD2 1 -0.278 0.425  -0.076 
ATOM   10325 N  N   . TYR D 1 137 ? -28.972 41.172  -31.547 1    110.72 ? 126 TYR D N   1 -0.266 0.377  -0.079 
ATOM   10326 C  CA  . TYR D 1 137 ? -29.511 39.94   -32.112 1    108.36 ? 126 TYR D CA  1 -0.27  0.366  -0.08  
ATOM   10327 C  C   . TYR D 1 137 ? -28.924 38.706  -31.429 1    106.91 ? 126 TYR D C   1 -0.265 0.355  -0.078 
ATOM   10328 O  O   . TYR D 1 137 ? -29.613 37.684  -31.305 1    106.31 ? 126 TYR D O   1 -0.271 0.345  -0.078 
ATOM   10329 C  CB  . TYR D 1 137 ? -29.3   39.885  -33.635 1    117.56 ? 126 TYR D CB  1 -0.269 0.366  -0.084 
ATOM   10330 C  CG  . TYR D 1 137 ? -29.895 38.625  -34.238 1    113.44 ? 126 TYR D CG  1 -0.274 0.354  -0.085 
ATOM   10331 C  CD1 . TYR D 1 137 ? -31.263 38.365  -34.126 1    110.87 ? 126 TYR D CD1 1 -0.286 0.352  -0.085 
ATOM   10332 C  CD2 . TYR D 1 137 ? -29.094 37.675  -34.867 1    109.29 ? 126 TYR D CD2 1 -0.267 0.345  -0.087 
ATOM   10333 C  CE1 . TYR D 1 137 ? -31.825 37.204  -34.635 1    108.9  ? 126 TYR D CE1 1 -0.292 0.341  -0.086 
ATOM   10334 C  CE2 . TYR D 1 137 ? -29.65  36.504  -35.39  1    115.46 ? 126 TYR D CE2 1 -0.272 0.335  -0.088 
ATOM   10335 C  CZ  . TYR D 1 137 ? -31.017 36.278  -35.265 1    115.73 ? 126 TYR D CZ  1 -0.284 0.332  -0.088 
ATOM   10336 O  OH  . TYR D 1 137 ? -31.586 35.13   -35.761 1    115.56 ? 126 TYR D OH  1 -0.289 0.322  -0.089 
ATOM   10337 N  N   . GLN D 1 138 ? -27.669 38.777  -30.974 1    105.36 ? 127 GLN D N   1 -0.254 0.355  -0.077 
ATOM   10338 C  CA  . GLN D 1 138 ? -27.126 37.707  -30.14  1    110.91 ? 127 GLN D CA  1 -0.249 0.346  -0.075 
ATOM   10339 C  C   . GLN D 1 138 ? -28.042 37.418  -28.956 1    111.96 ? 127 GLN D C   1 -0.257 0.343  -0.072 
ATOM   10340 O  O   . GLN D 1 138 ? -28.334 36.254  -28.651 1    112.83 ? 127 GLN D O   1 -0.26  0.332  -0.072 
ATOM   10341 C  CB  . GLN D 1 138 ? -25.726 38.071  -29.64  1    113.7  ? 127 GLN D CB  1 -0.236 0.349  -0.074 
ATOM   10342 C  CG  . GLN D 1 138 ? -24.597 37.776  -30.602 1    119.19 ? 127 GLN D CG  1 -0.225 0.346  -0.076 
ATOM   10343 C  CD  . GLN D 1 138 ? -23.418 37.084  -29.923 1    130.48 ? 127 GLN D CD  1 -0.215 0.34   -0.075 
ATOM   10344 O  OE1 . GLN D 1 138 ? -23.572 36.42   -28.887 1    124.89 ? 127 GLN D OE1 1 -0.216 0.334  -0.072 
ATOM   10345 N  NE2 . GLN D 1 138 ? -22.232 37.236  -30.51  1    135.8  ? 127 GLN D NE2 1 -0.204 0.341  -0.076 
ATOM   10346 N  N   . LEU D 1 139 ? -28.505 38.475  -28.272 1    107.98 ? 128 LEU D N   1 -0.261 0.353  -0.071 
ATOM   10347 C  CA  . LEU D 1 139 ? -29.392 38.289  -27.126 1    112.58 ? 128 LEU D CA  1 -0.269 0.351  -0.068 
ATOM   10348 C  C   . LEU D 1 139 ? -30.706 37.65   -27.553 1    111.17 ? 128 LEU D C   1 -0.281 0.345  -0.069 
ATOM   10349 O  O   . LEU D 1 139 ? -31.204 36.741  -26.878 1    108.99 ? 128 LEU D O   1 -0.286 0.337  -0.067 
ATOM   10350 C  CB  . LEU D 1 139 ? -29.657 39.624  -26.414 1    106.23 ? 128 LEU D CB  1 -0.272 0.363  -0.066 
ATOM   10351 C  CG  . LEU D 1 139 ? -28.873 40.004  -25.155 1    102.18 ? 128 LEU D CG  1 -0.265 0.367  -0.063 
ATOM   10352 C  CD1 . LEU D 1 139 ? -27.375 39.671  -25.24  1    100.85 ? 128 LEU D CD1 1 -0.251 0.364  -0.063 
ATOM   10353 C  CD2 . LEU D 1 139 ? -29.074 41.485  -24.901 1    106.14 ? 128 LEU D CD2 1 -0.266 0.38   -0.062 
ATOM   10354 N  N   . ILE D 1 140 ? -31.28  38.111  -28.674 1    107.62 ? 129 ILE D N   1 -0.287 0.349  -0.072 
ATOM   10355 C  CA  . ILE D 1 140 ? -32.573 37.591  -29.114 1    106.67 ? 129 ILE D CA  1 -0.299 0.344  -0.073 
ATOM   10356 C  C   . ILE D 1 140 ? -32.451 36.116  -29.45  1    107.2  ? 129 ILE D C   1 -0.297 0.331  -0.074 
ATOM   10357 O  O   . ILE D 1 140 ? -33.318 35.302  -29.104 1    102.48 ? 129 ILE D O   1 -0.305 0.324  -0.073 
ATOM   10358 C  CB  . ILE D 1 140 ? -33.099 38.4    -30.313 1    103.36 ? 129 ILE D CB  1 -0.303 0.352  -0.076 
ATOM   10359 C  CG1 . ILE D 1 140 ? -33.119 39.894  -29.988 1    102.69 ? 129 ILE D CG1 1 -0.304 0.366  -0.075 
ATOM   10360 C  CG2 . ILE D 1 140 ? -34.479 37.91   -30.723 1    102.68 ? 129 ILE D CG2 1 -0.316 0.347  -0.077 
ATOM   10361 C  CD1 . ILE D 1 140 ? -33.956 40.732  -30.948 1    95.04  ? 129 ILE D CD1 1 -0.311 0.373  -0.077 
ATOM   10362 N  N   . LYS D 1 141 ? -31.361 35.755  -30.122 1    112.23 ? 130 LYS D N   1 -0.287 0.328  -0.075 
ATOM   10363 C  CA  . LYS D 1 141 ? -31.079 34.359  -30.432 1    117.74 ? 130 LYS D CA  1 -0.285 0.315  -0.076 
ATOM   10364 C  C   . LYS D 1 141 ? -30.842 33.558  -29.151 1    114.41 ? 130 LYS D C   1 -0.283 0.308  -0.073 
ATOM   10365 O  O   . LYS D 1 141 ? -31.404 32.465  -28.978 1    110.51 ? 130 LYS D O   1 -0.288 0.298  -0.072 
ATOM   10366 C  CB  . LYS D 1 141 ? -29.87  34.298  -31.38  1    113.95 ? 130 LYS D CB  1 -0.274 0.314  -0.078 
ATOM   10367 C  CG  . LYS D 1 141 ? -29.641 33      -32.109 1    114.52 ? 130 LYS D CG  1 -0.272 0.302  -0.08  
ATOM   10368 C  CD  . LYS D 1 141 ? -28.555 33.19   -33.178 1    117.95 ? 130 LYS D CD  1 -0.262 0.304  -0.083 
ATOM   10369 C  CE  . LYS D 1 141 ? -28.514 31.997  -34.139 1    122.49 ? 130 LYS D CE  1 -0.261 0.293  -0.085 
ATOM   10370 N  NZ  . LYS D 1 141 ? -29.761 31.851  -34.974 1    120.38 ? 130 LYS D NZ  1 -0.273 0.292  -0.087 
ATOM   10371 N  N   . TYR D 1 142 ? -30.048 34.11   -28.222 1    115.01 ? 131 TYR D N   1 -0.275 0.313  -0.07  
ATOM   10372 C  CA  . TYR D 1 142 ? -29.744 33.398  -26.984 1    109.6  ? 131 TYR D CA  1 -0.273 0.306  -0.067 
ATOM   10373 C  C   . TYR D 1 142 ? -30.995 33.193  -26.141 1    103.18 ? 131 TYR D C   1 -0.284 0.304  -0.065 
ATOM   10374 O  O   . TYR D 1 142 ? -31.227 32.09   -25.636 1    106    ? 131 TYR D O   1 -0.286 0.294  -0.064 
ATOM   10375 C  CB  . TYR D 1 142 ? -28.663 34.143  -26.203 1    108    ? 131 TYR D CB  1 -0.263 0.313  -0.065 
ATOM   10376 C  CG  . TYR D 1 142 ? -27.248 33.786  -26.628 1    117.95 ? 131 TYR D CG  1 -0.25  0.31   -0.066 
ATOM   10377 C  CD1 . TYR D 1 142 ? -26.939 32.508  -27.097 1    116.76 ? 131 TYR D CD1 1 -0.247 0.298  -0.068 
ATOM   10378 C  CD2 . TYR D 1 142 ? -26.218 34.728  -26.56  1    117.05 ? 131 TYR D CD2 1 -0.24  0.318  -0.066 
ATOM   10379 C  CE1 . TYR D 1 142 ? -25.65  32.174  -27.475 1    116.24 ? 131 TYR D CE1 1 -0.235 0.295  -0.069 
ATOM   10380 C  CE2 . TYR D 1 142 ? -24.922 34.402  -26.939 1    116.67 ? 131 TYR D CE2 1 -0.228 0.315  -0.067 
ATOM   10381 C  CZ  . TYR D 1 142 ? -24.646 33.126  -27.395 1    122.79 ? 131 TYR D CZ  1 -0.226 0.304  -0.068 
ATOM   10382 O  OH  . TYR D 1 142 ? -23.359 32.8    -27.774 1    130.61 ? 131 TYR D OH  1 -0.214 0.301  -0.069 
ATOM   10383 N  N   . CYS D 1 143 ? -31.825 34.232  -26.002 1    102.26 ? 132 CYS D N   1 -0.292 0.314  -0.065 
ATOM   10384 C  CA  . CYS D 1 143 ? -33.091 34.101  -25.277 1    99.45  ? 132 CYS D CA  1 -0.303 0.313  -0.063 
ATOM   10385 C  C   . CYS D 1 143 ? -33.91  32.93   -25.789 1    102.32 ? 132 CYS D C   1 -0.311 0.302  -0.064 
ATOM   10386 O  O   . CYS D 1 143 ? -34.527 32.199  -25.007 1    98.85  ? 132 CYS D O   1 -0.316 0.295  -0.062 
ATOM   10387 C  CB  . CYS D 1 143 ? -33.909 35.384  -25.4   1    102.67 ? 132 CYS D CB  1 -0.311 0.324  -0.063 
ATOM   10388 S  SG  . CYS D 1 143 ? -33.199 36.819  -24.55  1    121.03 ? 132 CYS D SG  1 -0.304 0.337  -0.061 
ATOM   10389 N  N   . ILE D 1 144 ? -33.934 32.75   -27.11  1    113.39 ? 133 ILE D N   1 -0.311 0.3    -0.068 
ATOM   10390 C  CA  . ILE D 1 144 ? -34.727 31.692  -27.718 1    106.64 ? 133 ILE D CA  1 -0.318 0.29   -0.069 
ATOM   10391 C  C   . ILE D 1 144 ? -34.126 30.334  -27.388 1    101.11 ? 133 ILE D C   1 -0.313 0.278  -0.068 
ATOM   10392 O  O   . ILE D 1 144 ? -34.835 29.394  -27.012 1    95.25  ? 133 ILE D O   1 -0.319 0.269  -0.067 
ATOM   10393 C  CB  . ILE D 1 144 ? -34.827 31.942  -29.235 1    108.25 ? 133 ILE D CB  1 -0.319 0.293  -0.073 
ATOM   10394 C  CG1 . ILE D 1 144 ? -35.559 33.267  -29.479 1    106.77 ? 133 ILE D CG1 1 -0.326 0.305  -0.074 
ATOM   10395 C  CG2 . ILE D 1 144 ? -35.492 30.763  -29.969 1    107.62 ? 133 ILE D CG2 1 -0.325 0.282  -0.075 
ATOM   10396 C  CD1 . ILE D 1 144 ? -35.6   33.733  -30.927 1    116.89 ? 133 ILE D CD1 1 -0.326 0.309  -0.077 
ATOM   10397 N  N   . GLN D 1 145 ? -32.801 30.231  -27.504 1    104.26 ? 134 GLN D N   1 -0.301 0.277  -0.069 
ATOM   10398 C  CA  . GLN D 1 145 ? -32.115 28.977  -27.224 1    107.5  ? 134 GLN D CA  1 -0.294 0.266  -0.068 
ATOM   10399 C  C   . GLN D 1 145 ? -32.454 28.498  -25.828 1    108.03 ? 134 GLN D C   1 -0.297 0.261  -0.064 
ATOM   10400 O  O   . GLN D 1 145 ? -32.769 27.319  -25.613 1    104.77 ? 134 GLN D O   1 -0.3   0.25   -0.064 
ATOM   10401 C  CB  . GLN D 1 145 ? -30.61  29.19   -27.397 1    116.44 ? 134 GLN D CB  1 -0.281 0.268  -0.068 
ATOM   10402 C  CG  . GLN D 1 145 ? -29.747 27.945  -27.344 1    128.04 ? 134 GLN D CG  1 -0.273 0.256  -0.068 
ATOM   10403 C  CD  . GLN D 1 145 ? -28.338 28.221  -27.852 1    136.75 ? 134 GLN D CD  1 -0.26  0.259  -0.07  
ATOM   10404 O  OE1 . GLN D 1 145 ? -27.361 27.637  -27.36  1    135.96 ? 134 GLN D OE1 1 -0.251 0.253  -0.068 
ATOM   10405 N  NE2 . GLN D 1 145 ? -28.226 29.124  -28.841 1    127.47 ? 134 GLN D NE2 1 -0.259 0.267  -0.072 
ATOM   10406 N  N   . ALA D 1 146 ? -32.474 29.44   -24.885 1    110.06 ? 135 ALA D N   1 -0.298 0.27   -0.062 
ATOM   10407 C  CA  . ALA D 1 146 ? -32.716 29.189  -23.48  1    104.68 ? 135 ALA D CA  1 -0.3   0.267  -0.059 
ATOM   10408 C  C   . ALA D 1 146 ? -34.082 28.57   -23.198 1    108.93 ? 135 ALA D C   1 -0.312 0.262  -0.058 
ATOM   10409 O  O   . ALA D 1 146 ? -34.289 28.062  -22.089 1    111.48 ? 135 ALA D O   1 -0.314 0.257  -0.055 
ATOM   10410 C  CB  . ALA D 1 146 ? -32.553 30.508  -22.724 1    104.46 ? 135 ALA D CB  1 -0.298 0.28   -0.057 
ATOM   10411 N  N   . LYS D 1 147 ? -35.009 28.568  -24.159 1    109.76 ? 136 LYS D N   1 -0.321 0.262  -0.06  
ATOM   10412 C  CA  . LYS D 1 147 ? -36.332 28.009  -23.888 1    113.75 ? 136 LYS D CA  1 -0.333 0.257  -0.06  
ATOM   10413 C  C   . LYS D 1 147 ? -36.266 26.519  -23.55  1    113.06 ? 136 LYS D C   1 -0.332 0.243  -0.059 
ATOM   10414 O  O   . LYS D 1 147 ? -36.98  26.051  -22.657 1    108.42 ? 136 LYS D O   1 -0.339 0.239  -0.057 
ATOM   10415 C  CB  . LYS D 1 147 ? -37.261 28.249  -25.079 1    110.42 ? 136 LYS D CB  1 -0.341 0.259  -0.063 
ATOM   10416 C  CG  . LYS D 1 147 ? -38.733 28.368  -24.697 1    113.07 ? 136 LYS D CG  1 -0.355 0.26   -0.062 
ATOM   10417 C  CD  . LYS D 1 147 ? -39.349 29.63   -25.307 1    112.84 ? 136 LYS D CD  1 -0.361 0.272  -0.063 
ATOM   10418 C  CE  . LYS D 1 147 ? -40.832 29.749  -24.961 1    116.36 ? 136 LYS D CE  1 -0.374 0.273  -0.062 
ATOM   10419 N  NZ  . LYS D 1 147 ? -41.683 28.751  -25.696 1    116.51 ? 136 LYS D NZ  1 -0.382 0.263  -0.064 
ATOM   10420 N  N   . HIS D 1 148 ? -35.411 25.76   -24.248 1    114.94 ? 137 HIS D N   1 -0.325 0.236  -0.061 
ATOM   10421 C  CA  . HIS D 1 148 ? -35.361 24.308  -24.059 1    117.11 ? 137 HIS D CA  1 -0.324 0.223  -0.06  
ATOM   10422 C  C   . HIS D 1 148 ? -35.155 23.936  -22.592 1    119.82 ? 137 HIS D C   1 -0.322 0.219  -0.056 
ATOM   10423 O  O   . HIS D 1 148 ? -35.878 23.093  -22.043 1    122.33 ? 137 HIS D O   1 -0.329 0.212  -0.055 
ATOM   10424 C  CB  . HIS D 1 148 ? -34.247 23.707  -24.926 1    117.17 ? 137 HIS D CB  1 -0.314 0.217  -0.062 
ATOM   10425 C  CG  . HIS D 1 148 ? -34.207 22.205  -24.926 1    122.08 ? 137 HIS D CG  1 -0.313 0.203  -0.062 
ATOM   10426 N  ND1 . HIS D 1 148 ? -35.26  21.427  -24.491 1    125.9  ? 137 HIS D ND1 1 -0.323 0.196  -0.061 
ATOM   10427 C  CD2 . HIS D 1 148 ? -33.239 21.34   -25.317 1    120.93 ? 137 HIS D CD2 1 -0.305 0.196  -0.063 
ATOM   10428 C  CE1 . HIS D 1 148 ? -34.938 20.149  -24.603 1    128.18 ? 137 HIS D CE1 1 -0.32  0.185  -0.061 
ATOM   10429 N  NE2 . HIS D 1 148 ? -33.718 20.069  -25.104 1    122.42 ? 137 HIS D NE2 1 -0.309 0.184  -0.063 
ATOM   10430 N  N   . PHE D 1 149 ? -34.186 24.573  -21.932 1    117.57 ? 138 PHE D N   1 -0.313 0.225  -0.055 
ATOM   10431 C  CA  . PHE D 1 149 ? -33.745 24.142  -20.611 1    113.86 ? 138 PHE D CA  1 -0.309 0.221  -0.051 
ATOM   10432 C  C   . PHE D 1 149 ? -33.846 25.227  -19.544 1    114.11 ? 138 PHE D C   1 -0.31  0.231  -0.049 
ATOM   10433 O  O   . PHE D 1 149 ? -33.267 25.068  -18.465 1    113.91 ? 138 PHE D O   1 -0.305 0.23   -0.046 
ATOM   10434 C  CB  . PHE D 1 149 ? -32.31  23.616  -20.692 1    110.56 ? 138 PHE D CB  1 -0.296 0.216  -0.052 
ATOM   10435 C  CG  . PHE D 1 149 ? -32.216 22.187  -21.139 1    116.99 ? 138 PHE D CG  1 -0.295 0.203  -0.053 
ATOM   10436 C  CD1 . PHE D 1 149 ? -33.243 21.299  -20.858 1    116.18 ? 138 PHE D CD1 1 -0.305 0.195  -0.052 
ATOM   10437 C  CD2 . PHE D 1 149 ? -31.11  21.729  -21.847 1    120.47 ? 138 PHE D CD2 1 -0.285 0.199  -0.055 
ATOM   10438 C  CE1 . PHE D 1 149 ? -33.169 19.98   -21.27  1    116.79 ? 138 PHE D CE1 1 -0.304 0.183  -0.053 
ATOM   10439 C  CE2 . PHE D 1 149 ? -31.025 20.405  -22.258 1    115.56 ? 138 PHE D CE2 1 -0.284 0.187  -0.056 
ATOM   10440 C  CZ  . PHE D 1 149 ? -32.057 19.531  -21.964 1    117.45 ? 138 PHE D CZ  1 -0.294 0.179  -0.055 
ATOM   10441 N  N   . GLY D 1 150 ? -34.559 26.317  -19.804 1    109.08 ? 139 GLY D N   1 -0.317 0.241  -0.049 
ATOM   10442 C  CA  . GLY D 1 150 ? -34.679 27.383  -18.833 1    92.49  ? 139 GLY D CA  1 -0.318 0.251  -0.047 
ATOM   10443 C  C   . GLY D 1 150 ? -33.682 28.52   -18.961 1    99.08  ? 139 GLY D C   1 -0.309 0.261  -0.047 
ATOM   10444 O  O   . GLY D 1 150 ? -34.069 29.675  -18.779 1    100.2  ? 139 GLY D O   1 -0.312 0.272  -0.047 
ATOM   10445 N  N   . PHE D 1 151 ? -32.406 28.242  -19.248 1    101.7  ? 140 PHE D N   1 -0.297 0.259  -0.048 
ATOM   10446 C  CA  . PHE D 1 151 ? -31.424 29.321  -19.354 1    102.06 ? 140 PHE D CA  1 -0.288 0.269  -0.048 
ATOM   10447 C  C   . PHE D 1 151 ? -30.234 28.896  -20.212 1    108.38 ? 140 PHE D C   1 -0.277 0.265  -0.05  
ATOM   10448 O  O   . PHE D 1 151 ? -30.063 27.723  -20.55  1    113.1  ? 140 PHE D O   1 -0.276 0.254  -0.051 
ATOM   10449 C  CB  . PHE D 1 151 ? -30.964 29.826  -17.971 1    105.39 ? 140 PHE D CB  1 -0.284 0.273  -0.045 
ATOM   10450 C  CG  . PHE D 1 151 ? -30.729 28.739  -16.93  1    107.93 ? 140 PHE D CG  1 -0.282 0.263  -0.042 
ATOM   10451 C  CD1 . PHE D 1 151 ? -31.787 28.007  -16.388 1    107.79 ? 140 PHE D CD1 1 -0.291 0.257  -0.041 
ATOM   10452 C  CD2 . PHE D 1 151 ? -29.446 28.502  -16.434 1    111.2  ? 140 PHE D CD2 1 -0.27  0.261  -0.041 
ATOM   10453 C  CE1 . PHE D 1 151 ? -31.574 27.021  -15.411 1    108.78 ? 140 PHE D CE1 1 -0.289 0.248  -0.038 
ATOM   10454 C  CE2 . PHE D 1 151 ? -29.225 27.522  -15.449 1    109.56 ? 140 PHE D CE2 1 -0.268 0.252  -0.039 
ATOM   10455 C  CZ  . PHE D 1 151 ? -30.29  26.783  -14.943 1    108.27 ? 140 PHE D CZ  1 -0.278 0.245  -0.037 
ATOM   10456 N  N   . LYS D 1 152 ? -29.438 29.891  -20.6   1    107.68 ? 141 LYS D N   1 -0.27  0.274  -0.051 
ATOM   10457 C  CA  . LYS D 1 152 ? -28.238 29.722  -21.406 1    104.84 ? 141 LYS D CA  1 -0.259 0.272  -0.053 
ATOM   10458 C  C   . LYS D 1 152 ? -27.22  30.713  -20.865 1    112.04 ? 141 LYS D C   1 -0.249 0.281  -0.052 
ATOM   10459 O  O   . LYS D 1 152 ? -27.588 31.836  -20.511 1    111.33 ? 141 LYS D O   1 -0.253 0.292  -0.051 
ATOM   10460 C  CB  . LYS D 1 152 ? -28.548 29.969  -22.9   1    117.42 ? 141 LYS D CB  1 -0.262 0.275  -0.057 
ATOM   10461 C  CG  . LYS D 1 152 ? -27.409 29.759  -23.936 1    116.96 ? 141 LYS D CG  1 -0.251 0.273  -0.06  
ATOM   10462 C  CD  . LYS D 1 152 ? -26.875 28.319  -24.005 1    124.61 ? 141 LYS D CD  1 -0.246 0.26   -0.06  
ATOM   10463 C  CE  . LYS D 1 152 ? -27.966 27.277  -24.269 1    126.61 ? 141 LYS D CE  1 -0.256 0.25   -0.061 
ATOM   10464 N  NZ  . LYS D 1 152 ? -27.789 26.05   -23.392 1    135.3  ? 141 LYS D NZ  1 -0.255 0.239  -0.058 
ATOM   10465 N  N   . GLN D 1 153 ? -25.955 30.299  -20.765 1    112.68 ? 142 GLN D N   1 -0.238 0.278  -0.052 
ATOM   10466 C  CA  . GLN D 1 153 ? -24.909 31.096  -20.123 1    112.84 ? 142 GLN D CA  1 -0.228 0.285  -0.05  
ATOM   10467 C  C   . GLN D 1 153 ? -23.891 31.578  -21.15  1    117.27 ? 142 GLN D C   1 -0.219 0.289  -0.053 
ATOM   10468 O  O   . GLN D 1 153 ? -23.261 30.755  -21.819 1    127.79 ? 142 GLN D O   1 -0.213 0.282  -0.054 
ATOM   10469 C  CB  . GLN D 1 153 ? -24.204 30.276  -19.047 1    121.67 ? 142 GLN D CB  1 -0.222 0.277  -0.048 
ATOM   10470 C  CG  . GLN D 1 153 ? -22.8   30.766  -18.683 1    125.61 ? 142 GLN D CG  1 -0.209 0.282  -0.047 
ATOM   10471 C  CD  . GLN D 1 153 ? -22.258 30.057  -17.448 1    126.28 ? 142 GLN D CD  1 -0.204 0.275  -0.044 
ATOM   10472 O  OE1 . GLN D 1 153 ? -22.913 29.163  -16.907 1    121.89 ? 142 GLN D OE1 1 -0.21  0.267  -0.042 
ATOM   10473 N  NE2 . GLN D 1 153 ? -21.066 30.456  -16.992 1    130.26 ? 142 GLN D NE2 1 -0.193 0.279  -0.042 
ATOM   10474 N  N   . LEU D 1 154 ? -23.698 32.902  -21.244 1    114.22 ? 143 LEU D N   1 -0.217 0.302  -0.053 
ATOM   10475 C  CA  . LEU D 1 154 ? -22.708 33.47   -22.162 1    115.77 ? 143 LEU D CA  1 -0.208 0.307  -0.055 
ATOM   10476 C  C   . LEU D 1 154 ? -21.303 33.221  -21.621 1    123.22 ? 143 LEU D C   1 -0.195 0.304  -0.054 
ATOM   10477 O  O   . LEU D 1 154 ? -20.923 32.066  -21.405 1    129.75 ? 143 LEU D O   1 -0.192 0.294  -0.053 
ATOM   10478 C  CB  . LEU D 1 154 ? -22.922 34.972  -22.384 1    115.3  ? 143 LEU D CB  1 -0.21  0.32   -0.056 
ATOM   10479 C  CG  . LEU D 1 154 ? -24.3   35.592  -22.662 1    104.33 ? 143 LEU D CG  1 -0.223 0.326  -0.057 
ATOM   10480 C  CD1 . LEU D 1 154 ? -24.141 36.901  -23.454 1    99.45  ? 143 LEU D CD1 1 -0.221 0.338  -0.059 
ATOM   10481 C  CD2 . LEU D 1 154 ? -25.3   34.639  -23.312 1    105.1  ? 143 LEU D CD2 1 -0.232 0.317  -0.058 
ATOM   10482 N  N   . ASN D 1 155 ? -20.519 34.275  -21.377 1    125    ? 144 ASN D N   1 -0.188 0.314  -0.053 
ATOM   10483 C  CA  . ASN D 1 155 ? -19.254 34.058  -20.676 1    133.49 ? 144 ASN D CA  1 -0.176 0.312  -0.052 
ATOM   10484 C  C   . ASN D 1 155 ? -19.534 33.642  -19.226 1    124.34 ? 144 ASN D C   1 -0.179 0.308  -0.048 
ATOM   10485 O  O   . ASN D 1 155 ? -20.662 33.248  -18.905 1    118.59 ? 144 ASN D O   1 -0.189 0.305  -0.047 
ATOM   10486 C  CB  . ASN D 1 155 ? -18.335 35.296  -20.772 1    137.79 ? 144 ASN D CB  1 -0.168 0.323  -0.052 
ATOM   10487 C  CG  . ASN D 1 155 ? -18.848 36.517  -19.981 1    136.12 ? 144 ASN D CG  1 -0.173 0.335  -0.05  
ATOM   10488 O  OD1 . ASN D 1 155 ? -19.237 36.423  -18.798 1    129.37 ? 144 ASN D OD1 1 -0.176 0.334  -0.047 
ATOM   10489 N  ND2 . ASN D 1 155 ? -18.819 37.682  -20.638 1    130.95 ? 144 ASN D ND2 1 -0.172 0.345  -0.052 
ATOM   10490 N  N   . ALA D 1 156 ? -18.53  33.726  -18.345 1    124.52 ? 145 ALA D N   1 -0.17  0.309  -0.046 
ATOM   10491 C  CA  . ALA D 1 156 ? -18.655 33.118  -17.018 1    127.82 ? 145 ALA D CA  1 -0.171 0.303  -0.042 
ATOM   10492 C  C   . ALA D 1 156 ? -19.797 33.737  -16.213 1    122.7  ? 145 ALA D C   1 -0.181 0.309  -0.04  
ATOM   10493 O  O   . ALA D 1 156 ? -20.617 33.016  -15.634 1    109.87 ? 145 ALA D O   1 -0.189 0.303  -0.039 
ATOM   10494 C  CB  . ALA D 1 156 ? -17.336 33.229  -16.25  1    126.52 ? 145 ALA D CB  1 -0.159 0.305  -0.041 
ATOM   10495 N  N   . ASP D 1 157 ? -19.879 35.076  -16.191 1    126.66 ? 146 ASP D N   1 -0.182 0.321  -0.04  
ATOM   10496 C  CA  . ASP D 1 157 ? -20.765 35.812  -15.289 1    121.96 ? 146 ASP D CA  1 -0.19  0.328  -0.038 
ATOM   10497 C  C   . ASP D 1 157 ? -22.031 36.336  -15.976 1    119.7  ? 146 ASP D C   1 -0.202 0.333  -0.04  
ATOM   10498 O  O   . ASP D 1 157 ? -22.586 37.349  -15.546 1    114.11 ? 146 ASP D O   1 -0.207 0.342  -0.039 
ATOM   10499 C  CB  . ASP D 1 157 ? -20.025 36.99   -14.637 1    124.47 ? 146 ASP D CB  1 -0.184 0.339  -0.037 
ATOM   10500 C  CG  . ASP D 1 157 ? -18.698 36.588  -13.973 1    132.49 ? 146 ASP D CG  1 -0.171 0.335  -0.035 
ATOM   10501 O  OD1 . ASP D 1 157 ? -17.706 36.359  -14.71  1    134.84 ? 146 ASP D OD1 1 -0.162 0.333  -0.037 
ATOM   10502 O  OD2 . ASP D 1 157 ? -18.639 36.528  -12.716 1    130.67 ? 146 ASP D OD2 1 -0.171 0.335  -0.032 
ATOM   10503 N  N   . LEU D 1 158 ? -22.503 35.688  -17.042 1    125.62 ? 147 LEU D N   1 -0.206 0.327  -0.043 
ATOM   10504 C  CA  . LEU D 1 158 ? -23.757 36.079  -17.683 1    120.27 ? 147 LEU D CA  1 -0.218 0.331  -0.044 
ATOM   10505 C  C   . LEU D 1 158 ? -24.651 34.864  -17.83  1    112.97 ? 147 LEU D C   1 -0.226 0.319  -0.045 
ATOM   10506 O  O   . LEU D 1 158 ? -24.187 33.775  -18.187 1    118.5  ? 147 LEU D O   1 -0.222 0.31   -0.045 
ATOM   10507 C  CB  . LEU D 1 158 ? -23.555 36.725  -19.077 1    109.14 ? 147 LEU D CB  1 -0.216 0.337  -0.048 
ATOM   10508 C  CG  . LEU D 1 158 ? -22.955 38.127  -19.141 1    113.22 ? 147 LEU D CG  1 -0.21  0.349  -0.048 
ATOM   10509 C  CD1 . LEU D 1 158 ? -22.989 38.642  -20.558 1    117.04 ? 147 LEU D CD1 1 -0.211 0.354  -0.051 
ATOM   10510 C  CD2 . LEU D 1 158 ? -23.686 39.081  -18.235 1    110.38 ? 147 LEU D CD2 1 -0.217 0.358  -0.046 
ATOM   10511 N  N   . VAL D 1 159 ? -25.93  35.057  -17.528 1    102.54 ? 148 VAL D N   1 -0.238 0.321  -0.044 
ATOM   10512 C  CA  . VAL D 1 159 ? -26.969 34.068  -17.779 1    101.15 ? 148 VAL D CA  1 -0.247 0.312  -0.044 
ATOM   10513 C  C   . VAL D 1 159 ? -28.191 34.815  -18.273 1    106.03 ? 148 VAL D C   1 -0.258 0.319  -0.046 
ATOM   10514 O  O   . VAL D 1 159 ? -28.549 35.86   -17.721 1    100.66 ? 148 VAL D O   1 -0.262 0.329  -0.044 
ATOM   10515 C  CB  . VAL D 1 159 ? -27.334 33.246  -16.532 1    104.06 ? 148 VAL D CB  1 -0.25  0.305  -0.041 
ATOM   10516 C  CG1 . VAL D 1 159 ? -28.436 32.239  -16.869 1    101.21 ? 148 VAL D CG1 1 -0.261 0.295  -0.042 
ATOM   10517 C  CG2 . VAL D 1 159 ? -26.104 32.559  -15.949 1    108.07 ? 148 VAL D CG2 1 -0.239 0.298  -0.04  
ATOM   10518 N  N   . VAL D 1 160 ? -28.828 34.269  -19.318 1    112.21 ? 149 VAL D N   1 -0.264 0.314  -0.048 
ATOM   10519 C  CA  . VAL D 1 160 ? -30.017 34.843  -19.934 1    103.17 ? 149 VAL D CA  1 -0.275 0.319  -0.05  
ATOM   10520 C  C   . VAL D 1 160 ? -31.125 33.793  -19.93  1    100.69 ? 149 VAL D C   1 -0.285 0.31   -0.05  
ATOM   10521 O  O   . VAL D 1 160 ? -30.871 32.584  -19.976 1    102.44 ? 149 VAL D O   1 -0.283 0.299  -0.05  
ATOM   10522 C  CB  . VAL D 1 160 ? -29.712 35.362  -21.363 1    104    ? 149 VAL D CB  1 -0.272 0.324  -0.053 
ATOM   10523 C  CG1 . VAL D 1 160 ? -28.934 34.327  -22.141 1    106.46 ? 149 VAL D CG1 1 -0.265 0.315  -0.055 
ATOM   10524 C  CG2 . VAL D 1 160 ? -30.983 35.734  -22.108 1    99.24  ? 149 VAL D CG2 1 -0.284 0.327  -0.055 
ATOM   10525 N  N   . THR D 1 161 ? -32.368 34.27   -19.802 1    96.52  ? 150 THR D N   1 -0.297 0.314  -0.049 
ATOM   10526 C  CA  . THR D 1 161 ? -33.569 33.445  -19.75  1    98.66  ? 150 THR D CA  1 -0.308 0.306  -0.049 
ATOM   10527 C  C   . THR D 1 161 ? -34.404 33.739  -20.989 1    101.43 ? 150 THR D C   1 -0.315 0.309  -0.052 
ATOM   10528 O  O   . THR D 1 161 ? -34.034 34.617  -21.787 1    103.18 ? 150 THR D O   1 -0.312 0.317  -0.054 
ATOM   10529 C  CB  . THR D 1 161 ? -34.389 33.726  -18.478 1    103.67 ? 150 THR D CB  1 -0.315 0.309  -0.046 
ATOM   10530 O  OG1 . THR D 1 161 ? -35.107 34.958  -18.63  1    100.1  ? 150 THR D OG1 1 -0.322 0.32   -0.047 
ATOM   10531 C  CG2 . THR D 1 161 ? -33.508 33.781  -17.221 1    98.09  ? 150 THR D CG2 1 -0.307 0.31   -0.043 
ATOM   10532 N  N   . PRO D 1 162 ? -35.534 33.048  -21.191 1    100.35 ? 151 PRO D N   1 -0.326 0.303  -0.053 
ATOM   10533 C  CA  . PRO D 1 162 ? -36.352 33.346  -22.39  1    100.76 ? 151 PRO D CA  1 -0.333 0.306  -0.056 
ATOM   10534 C  C   . PRO D 1 162 ? -37.026 34.714  -22.384 1    96.13  ? 151 PRO D C   1 -0.339 0.318  -0.056 
ATOM   10535 O  O   . PRO D 1 162 ? -37.144 35.334  -23.446 1    96.79  ? 151 PRO D O   1 -0.34  0.324  -0.059 
ATOM   10536 C  CB  . PRO D 1 162 ? -37.38  32.209  -22.396 1    105.24 ? 151 PRO D CB  1 -0.343 0.295  -0.056 
ATOM   10537 C  CG  . PRO D 1 162 ? -36.719 31.102  -21.639 1    104.16 ? 151 PRO D CG  1 -0.336 0.285  -0.054 
ATOM   10538 C  CD  . PRO D 1 162 ? -35.91  31.759  -20.582 1    98.21  ? 151 PRO D CD  1 -0.329 0.291  -0.051 
ATOM   10539 N  N   . LYS D 1 163 ? -37.5   35.204  -21.24  1    102.7  ? 152 LYS D N   1 -0.344 0.323  -0.053 
ATOM   10540 C  CA  . LYS D 1 163 ? -38.144 36.513  -21.219 1    93.99  ? 152 LYS D CA  1 -0.35  0.335  -0.053 
ATOM   10541 C  C   . LYS D 1 163 ? -37.178 37.636  -20.909 1    90.82  ? 152 LYS D C   1 -0.341 0.345  -0.052 
ATOM   10542 O  O   . LYS D 1 163 ? -37.617 38.777  -20.733 1    88.02  ? 152 LYS D O   1 -0.345 0.355  -0.052 
ATOM   10543 C  CB  . LYS D 1 163 ? -39.296 36.555  -20.22  1    91.54  ? 152 LYS D CB  1 -0.36  0.335  -0.05  
ATOM   10544 C  CG  . LYS D 1 163 ? -40.547 35.795  -20.624 1    93.66  ? 152 LYS D CG  1 -0.372 0.328  -0.051 
ATOM   10545 C  CD  . LYS D 1 163 ? -41.228 36.409  -21.817 1    101.41 ? 152 LYS D CD  1 -0.378 0.334  -0.054 
ATOM   10546 C  CE  . LYS D 1 163 ? -42.667 35.894  -21.994 1    111.98 ? 152 LYS D CE  1 -0.391 0.329  -0.055 
ATOM   10547 N  NZ  . LYS D 1 163 ? -43.43  36.602  -23.094 1    108.25 ? 152 LYS D NZ  1 -0.398 0.335  -0.058 
ATOM   10548 N  N   . THR D 1 164 ? -35.873 37.356  -20.886 1    92.62  ? 153 THR D N   1 -0.329 0.342  -0.052 
ATOM   10549 C  CA  . THR D 1 164 ? -34.895 38.385  -20.538 1    95.08  ? 153 THR D CA  1 -0.32  0.352  -0.051 
ATOM   10550 C  C   . THR D 1 164 ? -34.986 39.584  -21.478 1    89.63  ? 153 THR D C   1 -0.321 0.363  -0.054 
ATOM   10551 O  O   . THR D 1 164 ? -35.224 40.716  -21.035 1    84.32  ? 153 THR D O   1 -0.323 0.373  -0.053 
ATOM   10552 C  CB  . THR D 1 164 ? -33.488 37.795  -20.552 1    102.66 ? 153 THR D CB  1 -0.307 0.346  -0.051 
ATOM   10553 O  OG1 . THR D 1 164 ? -33.344 36.825  -19.493 1    98.65  ? 153 THR D OG1 1 -0.306 0.337  -0.049 
ATOM   10554 C  CG2 . THR D 1 164 ? -32.463 38.916  -20.41  1    98.54  ? 153 THR D CG2 1 -0.297 0.357  -0.051 
ATOM   10555 N  N   . PHE D 1 165 ? -34.816 39.35   -22.786 1    102.39 ? 154 PHE D N   1 -0.319 0.361  -0.057 
ATOM   10556 C  CA  . PHE D 1 165 ? -34.891 40.445  -23.762 1    96.34  ? 154 PHE D CA  1 -0.32  0.371  -0.059 
ATOM   10557 C  C   . PHE D 1 165 ? -36.154 41.286  -23.585 1    95.88  ? 154 PHE D C   1 -0.331 0.378  -0.059 
ATOM   10558 O  O   . PHE D 1 165 ? -36.086 42.522  -23.613 1    91.49  ? 154 PHE D O   1 -0.331 0.39   -0.059 
ATOM   10559 C  CB  . PHE D 1 165 ? -34.817 39.919  -25.197 1    97.95  ? 154 PHE D CB  1 -0.319 0.366  -0.063 
ATOM   10560 C  CG  . PHE D 1 165 ? -34.735 41.023  -26.222 1    100.09 ? 154 PHE D CG  1 -0.318 0.376  -0.065 
ATOM   10561 C  CD1 . PHE D 1 165 ? -33.506 41.554  -26.586 1    96.63  ? 154 PHE D CD1 1 -0.307 0.381  -0.066 
ATOM   10562 C  CD2 . PHE D 1 165 ? -35.886 41.568  -26.774 1    87.59  ? 154 PHE D CD2 1 -0.329 0.381  -0.067 
ATOM   10563 C  CE1 . PHE D 1 165 ? -33.43  42.581  -27.482 1    81.98  ? 154 PHE D CE1 1 -0.306 0.39   -0.069 
ATOM   10564 C  CE2 . PHE D 1 165 ? -35.807 42.602  -27.661 1    85.71  ? 154 PHE D CE2 1 -0.328 0.39   -0.069 
ATOM   10565 C  CZ  . PHE D 1 165 ? -34.584 43.104  -28.019 1    85.33  ? 154 PHE D CZ  1 -0.317 0.395  -0.07  
ATOM   10566 N  N   . GLU D 1 166 ? -37.317 40.644  -23.403 1    97.49  ? 155 GLU D N   1 -0.342 0.372  -0.058 
ATOM   10567 C  CA  . GLU D 1 166 ? -38.52  41.414  -23.097 1    92.74  ? 155 GLU D CA  1 -0.353 0.38   -0.058 
ATOM   10568 C  C   . GLU D 1 166 ? -38.264 42.372  -21.953 1    97.49  ? 155 GLU D C   1 -0.351 0.388  -0.055 
ATOM   10569 O  O   . GLU D 1 166 ? -38.473 43.586  -22.077 1    100.46 ? 155 GLU D O   1 -0.353 0.399  -0.055 
ATOM   10570 C  CB  . GLU D 1 166 ? -39.691 40.505  -22.737 1    87.91  ? 155 GLU D CB  1 -0.364 0.371  -0.057 
ATOM   10571 C  CG  . GLU D 1 166 ? -40.971 41.303  -22.567 1    94.45  ? 155 GLU D CG  1 -0.375 0.379  -0.056 
ATOM   10572 C  CD  . GLU D 1 166 ? -42.212 40.469  -22.801 1    101.56 ? 155 GLU D CD  1 -0.387 0.371  -0.057 
ATOM   10573 O  OE1 . GLU D 1 166 ? -43.309 41.063  -22.978 1    102.65 ? 155 GLU D OE1 1 -0.397 0.376  -0.057 
ATOM   10574 O  OE2 . GLU D 1 166 ? -42.088 39.226  -22.816 1    97.8   ? 155 GLU D OE2 1 -0.386 0.359  -0.057 
ATOM   10575 N  N   . ILE D 1 167 ? -37.744 41.836  -20.851 1    97.15  ? 156 ILE D N   1 -0.346 0.383  -0.052 
ATOM   10576 C  CA  . ILE D 1 167 ? -37.737 42.545  -19.577 1    93.56  ? 156 ILE D CA  1 -0.346 0.39   -0.049 
ATOM   10577 C  C   . ILE D 1 167 ? -36.892 43.809  -19.657 1    98.84  ? 156 ILE D C   1 -0.338 0.401  -0.049 
ATOM   10578 O  O   . ILE D 1 167 ? -37.312 44.882  -19.204 1    106.68 ? 156 ILE D O   1 -0.342 0.411  -0.048 
ATOM   10579 C  CB  . ILE D 1 167 ? -37.241 41.6    -18.475 1    94.71  ? 156 ILE D CB  1 -0.341 0.381  -0.046 
ATOM   10580 C  CG1 . ILE D 1 167 ? -38.35  40.629  -18.097 1    90.68  ? 156 ILE D CG1 1 -0.351 0.372  -0.045 
ATOM   10581 C  CG2 . ILE D 1 167 ? -36.665 42.366  -17.301 1    91.68  ? 156 ILE D CG2 1 -0.336 0.388  -0.043 
ATOM   10582 C  CD1 . ILE D 1 167 ? -37.803 39.474  -17.355 1    90.53  ? 156 ILE D CD1 1 -0.346 0.362  -0.043 
ATOM   10583 N  N   . LEU D 1 168 ? -35.681 43.704  -20.22  1    91.67  ? 157 LEU D N   1 -0.327 0.401  -0.05  
ATOM   10584 C  CA  . LEU D 1 168 ? -34.836 44.889  -20.301 1    93.29  ? 157 LEU D CA  1 -0.319 0.411  -0.051 
ATOM   10585 C  C   . LEU D 1 168 ? -35.469 45.967  -21.18  1    103.08 ? 157 LEU D C   1 -0.325 0.421  -0.053 
ATOM   10586 O  O   . LEU D 1 168 ? -35.319 47.162  -20.886 1    102.33 ? 157 LEU D O   1 -0.324 0.432  -0.052 
ATOM   10587 C  CB  . LEU D 1 168 ? -33.445 44.522  -20.815 1    96.63  ? 157 LEU D CB  1 -0.306 0.408  -0.052 
ATOM   10588 C  CG  . LEU D 1 168 ? -32.742 43.277  -20.273 1    96.22  ? 157 LEU D CG  1 -0.3   0.397  -0.051 
ATOM   10589 C  CD1 . LEU D 1 168 ? -32.794 42.148  -21.293 1    91.7   ? 157 LEU D CD1 1 -0.301 0.386  -0.053 
ATOM   10590 C  CD2 . LEU D 1 168 ? -31.297 43.607  -19.87  1    99.66  ? 157 LEU D CD2 1 -0.287 0.4    -0.05  
ATOM   10591 N  N   . ILE D 1 169 ? -36.207 45.578  -22.234 1    95.21  ? 158 ILE D N   1 -0.332 0.418  -0.056 
ATOM   10592 C  CA  . ILE D 1 169 ? -36.882 46.579  -23.059 1    97.31  ? 158 ILE D CA  1 -0.338 0.427  -0.058 
ATOM   10593 C  C   . ILE D 1 169 ? -38.007 47.247  -22.279 1    101.42 ? 158 ILE D C   1 -0.348 0.433  -0.056 
ATOM   10594 O  O   . ILE D 1 169 ? -38.188 48.47   -22.355 1    102.79 ? 158 ILE D O   1 -0.35  0.444  -0.056 
ATOM   10595 C  CB  . ILE D 1 169 ? -37.399 45.967  -24.376 1    101.23 ? 158 ILE D CB  1 -0.343 0.421  -0.061 
ATOM   10596 C  CG1 . ILE D 1 169 ? -36.238 45.732  -25.35  1    93.85  ? 158 ILE D CG1 1 -0.332 0.419  -0.063 
ATOM   10597 C  CG2 . ILE D 1 169 ? -38.47  46.872  -25.007 1    93.46  ? 158 ILE D CG2 1 -0.353 0.43   -0.062 
ATOM   10598 C  CD1 . ILE D 1 169 ? -35.319 46.939  -25.491 1    88.49  ? 158 ILE D CD1 1 -0.324 0.43   -0.064 
ATOM   10599 N  N   . ARG D 1 170 ? -38.784 46.464  -21.522 1    102.73 ? 159 ARG D N   1 -0.355 0.426  -0.054 
ATOM   10600 C  CA  . ARG D 1 170 ? -39.821 47.062  -20.682 1    105.5  ? 159 ARG D CA  1 -0.365 0.431  -0.052 
ATOM   10601 C  C   . ARG D 1 170 ? -39.216 47.948  -19.596 1    106.74 ? 159 ARG D C   1 -0.359 0.439  -0.049 
ATOM   10602 O  O   . ARG D 1 170 ? -39.732 49.039  -19.321 1    108.69 ? 159 ARG D O   1 -0.364 0.449  -0.048 
ATOM   10603 C  CB  . ARG D 1 170 ? -40.71  45.977  -20.068 1    102.92 ? 159 ARG D CB  1 -0.373 0.421  -0.05  
ATOM   10604 C  CG  . ARG D 1 170 ? -41.663 45.33   -21.072 1    106.74 ? 159 ARG D CG  1 -0.382 0.415  -0.053 
ATOM   10605 C  CD  . ARG D 1 170 ? -42.849 44.656  -20.397 1    107.2  ? 159 ARG D CD  1 -0.393 0.409  -0.051 
ATOM   10606 N  NE  . ARG D 1 170 ? -43.662 43.893  -21.339 1    116.08 ? 159 ARG D NE  1 -0.4   0.402  -0.053 
ATOM   10607 C  CZ  . ARG D 1 170 ? -44.8   44.319  -21.881 1    116.24 ? 159 ARG D CZ  1 -0.411 0.406  -0.055 
ATOM   10608 N  NH1 . ARG D 1 170 ? -45.283 45.524  -21.616 1    121.66 ? 159 ARG D NH1 1 -0.415 0.417  -0.054 
ATOM   10609 N  NH2 . ARG D 1 170 ? -45.478 43.51   -22.694 1    107.47 ? 159 ARG D NH2 1 -0.417 0.399  -0.057 
ATOM   10610 N  N   . ASP D 1 171 ? -38.123 47.505  -18.969 1    110.69 ? 160 ASP D N   1 -0.349 0.435  -0.047 
ATOM   10611 C  CA  . ASP D 1 171 ? -37.443 48.346  -17.984 1    109.62 ? 160 ASP D CA  1 -0.343 0.443  -0.045 
ATOM   10612 C  C   . ASP D 1 171 ? -36.903 49.611  -18.648 1    110.11 ? 160 ASP D C   1 -0.338 0.455  -0.047 
ATOM   10613 O  O   . ASP D 1 171 ? -37.085 50.723  -18.137 1    112.04 ? 160 ASP D O   1 -0.34  0.465  -0.045 
ATOM   10614 C  CB  . ASP D 1 171 ? -36.324 47.549  -17.293 1    103.88 ? 160 ASP D CB  1 -0.333 0.436  -0.043 
ATOM   10615 C  CG  . ASP D 1 171 ? -35.556 48.365  -16.226 1    121.31 ? 160 ASP D CG  1 -0.326 0.443  -0.041 
ATOM   10616 O  OD1 . ASP D 1 171 ? -36.154 49.252  -15.559 1    120.05 ? 160 ASP D OD1 1 -0.331 0.451  -0.039 
ATOM   10617 O  OD2 . ASP D 1 171 ? -34.338 48.1    -16.045 1    122.23 ? 160 ASP D OD2 1 -0.315 0.441  -0.04  
ATOM   10618 N  N   . CYS D 1 172 ? -36.275 49.464  -19.819 1    107.03 ? 161 CYS D N   1 -0.332 0.453  -0.049 
ATOM   10619 C  CA  . CYS D 1 172 ? -35.745 50.632  -20.516 1    110.03 ? 161 CYS D CA  1 -0.328 0.464  -0.051 
ATOM   10620 C  C   . CYS D 1 172 ? -36.866 51.538  -21.017 1    111.11 ? 161 CYS D C   1 -0.338 0.472  -0.052 
ATOM   10621 O  O   . CYS D 1 172 ? -36.767 52.768  -20.923 1    108.45 ? 161 CYS D O   1 -0.337 0.484  -0.052 
ATOM   10622 C  CB  . CYS D 1 172 ? -34.851 50.192  -21.673 1    111.04 ? 161 CYS D CB  1 -0.319 0.46   -0.054 
ATOM   10623 S  SG  . CYS D 1 172 ? -33.209 49.645  -21.17  1    126.04 ? 161 CYS D SG  1 -0.304 0.455  -0.053 
ATOM   10624 N  N   . ALA D 1 173 ? -37.945 50.947  -21.538 1    107.1  ? 162 ALA D N   1 -0.348 0.467  -0.054 
ATOM   10625 C  CA  . ALA D 1 173 ? -39.092 51.746  -21.953 1    109.7  ? 162 ALA D CA  1 -0.358 0.474  -0.055 
ATOM   10626 C  C   . ALA D 1 173 ? -39.693 52.516  -20.778 1    111.26 ? 162 ALA D C   1 -0.364 0.481  -0.052 
ATOM   10627 O  O   . ALA D 1 173 ? -40.075 53.684  -20.926 1    107.76 ? 162 ALA D O   1 -0.367 0.492  -0.052 
ATOM   10628 C  CB  . ALA D 1 173 ? -40.149 50.854  -22.61  1    107.53 ? 162 ALA D CB  1 -0.368 0.466  -0.056 
ATOM   10629 N  N   . THR D 1 174 ? -39.77  51.885  -19.599 1    118.27 ? 163 THR D N   1 -0.364 0.475  -0.049 
ATOM   10630 C  CA  . THR D 1 174 ? -40.418 52.52   -18.45  1    112.68 ? 163 THR D CA  1 -0.37  0.481  -0.046 
ATOM   10631 C  C   . THR D 1 174 ? -39.712 53.811  -18.055 1    111.48 ? 163 THR D C   1 -0.364 0.493  -0.045 
ATOM   10632 O  O   . THR D 1 174 ? -40.345 54.867  -17.93  1    111.77 ? 163 THR D O   1 -0.37  0.503  -0.045 
ATOM   10633 C  CB  . THR D 1 174 ? -40.469 51.552  -17.278 1    106.09 ? 163 THR D CB  1 -0.371 0.472  -0.043 
ATOM   10634 O  OG1 . THR D 1 174 ? -41.28  50.43   -17.634 1    107.12 ? 163 THR D OG1 1 -0.378 0.462  -0.044 
ATOM   10635 C  CG2 . THR D 1 174 ? -41.085 52.229  -16.089 1    114.33 ? 163 THR D CG2 1 -0.377 0.479  -0.04  
ATOM   10636 N  N   . THR D 1 175 ? -38.392 53.752  -17.889 1    109.95 ? 164 THR D N   1 -0.352 0.493  -0.045 
ATOM   10637 C  CA  . THR D 1 175 ? -37.624 54.949  -17.575 1    116.47 ? 164 THR D CA  1 -0.345 0.504  -0.044 
ATOM   10638 C  C   . THR D 1 175 ? -37.597 55.949  -18.742 1    117.04 ? 164 THR D C   1 -0.345 0.513  -0.047 
ATOM   10639 O  O   . THR D 1 175 ? -37.332 57.137  -18.517 1    120.75 ? 164 THR D O   1 -0.342 0.524  -0.046 
ATOM   10640 C  CB  . THR D 1 175 ? -36.206 54.532  -17.14  1    113.73 ? 164 THR D CB  1 -0.332 0.5    -0.043 
ATOM   10641 O  OG1 . THR D 1 175 ? -36.294 53.525  -16.121 1    102.62 ? 164 THR D OG1 1 -0.333 0.491  -0.04  
ATOM   10642 C  CG2 . THR D 1 175 ? -35.41  55.719  -16.601 1    108    ? 164 THR D CG2 1 -0.325 0.511  -0.041 
ATOM   10643 N  N   . LEU D 1 176 ? -37.897 55.517  -19.973 1    115.19 ? 165 LEU D N   1 -0.347 0.509  -0.05  
ATOM   10644 C  CA  . LEU D 1 176 ? -37.937 56.445  -21.105 1    119.8  ? 165 LEU D CA  1 -0.348 0.517  -0.053 
ATOM   10645 C  C   . LEU D 1 176 ? -39.301 57.125  -21.278 1    118.03 ? 165 LEU D C   1 -0.36  0.524  -0.053 
ATOM   10646 O  O   . LEU D 1 176 ? -39.356 58.323  -21.589 1    109.86 ? 165 LEU D O   1 -0.361 0.534  -0.054 
ATOM   10647 C  CB  . LEU D 1 176 ? -37.546 55.722  -22.402 1    115.31 ? 165 LEU D CB  1 -0.344 0.511  -0.056 
ATOM   10648 C  CG  . LEU D 1 176 ? -36.072 55.322  -22.566 1    115.82 ? 165 LEU D CG  1 -0.331 0.507  -0.056 
ATOM   10649 C  CD1 . LEU D 1 176 ? -35.847 54.461  -23.819 1    110.04 ? 165 LEU D CD1 1 -0.329 0.499  -0.059 
ATOM   10650 C  CD2 . LEU D 1 176 ? -35.154 56.545  -22.567 1    109.53 ? 165 LEU D CD2 1 -0.322 0.518  -0.056 
ATOM   10651 N  N   . PHE D 1 177 ? -40.401 56.388  -21.08  1    118.98 ? 166 PHE D N   1 -0.37  0.517  -0.053 
ATOM   10652 C  CA  . PHE D 1 177 ? -41.758 56.926  -21.185 1    121.06 ? 166 PHE D CA  1 -0.383 0.522  -0.053 
ATOM   10653 C  C   . PHE D 1 177 ? -42.29  57.459  -19.846 1    127.52 ? 166 PHE D C   1 -0.388 0.527  -0.05  
ATOM   10654 O  O   . PHE D 1 177 ? -43.504 57.667  -19.702 1    124.35 ? 166 PHE D O   1 -0.399 0.528  -0.049 
ATOM   10655 C  CB  . PHE D 1 177 ? -42.744 55.871  -21.716 1    120.07 ? 166 PHE D CB  1 -0.392 0.512  -0.054 
ATOM   10656 C  CG  . PHE D 1 177 ? -42.317 55.167  -22.978 1    113.6  ? 166 PHE D CG  1 -0.388 0.506  -0.057 
ATOM   10657 C  CD1 . PHE D 1 177 ? -41.235 55.596  -23.727 1    111.98 ? 166 PHE D CD1 1 -0.378 0.509  -0.059 
ATOM   10658 C  CD2 . PHE D 1 177 ? -43.031 54.059  -23.415 1    118.82 ? 166 PHE D CD2 1 -0.394 0.495  -0.058 
ATOM   10659 C  CE1 . PHE D 1 177 ? -40.864 54.922  -24.87  1    113.86 ? 166 PHE D CE1 1 -0.374 0.503  -0.062 
ATOM   10660 C  CE2 . PHE D 1 177 ? -42.67  53.382  -24.563 1    117.52 ? 166 PHE D CE2 1 -0.391 0.489  -0.061 
ATOM   10661 C  CZ  . PHE D 1 177 ? -41.584 53.816  -25.293 1    117.75 ? 166 PHE D CZ  1 -0.381 0.493  -0.063 
ATOM   10662 N  N   . ASN D 1 178 ? -41.428 57.643  -18.857 1    124.38 ? 167 ASN D N   1 -0.38  0.528  -0.047 
ATOM   10663 C  CA  . ASN D 1 178 ? -41.776 58.424  -17.675 1    128.39 ? 167 ASN D CA  1 -0.383 0.535  -0.044 
ATOM   10664 C  C   . ASN D 1 178 ? -40.773 59.564  -17.543 1    134.18 ? 167 ASN D C   1 -0.374 0.546  -0.044 
ATOM   10665 O  O   . ASN D 1 178 ? -39.6   59.323  -17.188 1    128.66 ? 167 ASN D O   1 -0.363 0.544  -0.043 
ATOM   10666 C  CB  . ASN D 1 178 ? -41.795 57.559  -16.416 1    132.18 ? 167 ASN D CB  1 -0.383 0.527  -0.041 
ATOM   10667 C  CG  . ASN D 1 178 ? -41.589 58.374  -15.136 1    131.98 ? 167 ASN D CG  1 -0.381 0.535  -0.038 
ATOM   10668 O  OD1 . ASN D 1 178 ? -40.474 58.807  -14.848 1    126.35 ? 167 ASN D OD1 1 -0.371 0.539  -0.037 
ATOM   10669 N  ND2 . ASN D 1 178 ? -42.662 58.571  -14.362 1    127.82 ? 167 ASN D ND2 1 -0.391 0.537  -0.036 
ATOM   10670 N  N   . PRO D 1 179 ? -41.159 60.804  -17.863 1    142.82 ? 168 PRO D N   1 -0.377 0.557  -0.045 
ATOM   10671 C  CA  . PRO D 1 179 ? -40.304 61.96   -17.492 1    143.34 ? 168 PRO D CA  1 -0.369 0.568  -0.044 
ATOM   10672 C  C   . PRO D 1 179 ? -40.486 62.4    -16.036 1    135.45 ? 168 PRO D C   1 -0.371 0.572  -0.04  
ATOM   10673 O  O   . PRO D 1 179 ? -41.255 63.313  -15.71  1    136.42 ? 168 PRO D O   1 -0.378 0.58   -0.039 
ATOM   10674 C  CB  . PRO D 1 179 ? -40.743 63.041  -18.487 1    144.2  ? 168 PRO D CB  1 -0.373 0.578  -0.046 
ATOM   10675 C  CG  . PRO D 1 179 ? -42.144 62.662  -18.929 1    142.76 ? 168 PRO D CG  1 -0.386 0.574  -0.047 
ATOM   10676 C  CD  . PRO D 1 179 ? -42.212 61.156  -18.843 1    138.95 ? 168 PRO D CD  1 -0.387 0.56   -0.047 
ATOM   10677 N  N   . ALA D 1 180 ? -39.76  61.738  -15.125 1    129.36 ? 169 ALA D N   1 -0.364 0.566  -0.038 
ATOM   10678 C  CA  . ALA D 1 180 ? -39.712 62.124  -13.713 1    126    ? 169 ALA D CA  1 -0.364 0.569  -0.034 
ATOM   10679 C  C   . ALA D 1 180 ? -38.333 62.683  -13.386 1    117.09 ? 169 ALA D C   1 -0.351 0.574  -0.033 
ATOM   10680 O  O   . ALA D 1 180 ? -37.32  61.998  -13.579 1    109.86 ? 169 ALA D O   1 -0.342 0.568  -0.034 
ATOM   10681 C  CB  . ALA D 1 180 ? -40.041 60.957  -12.782 1    120.16 ? 169 ALA D CB  1 -0.367 0.559  -0.032 
ATOM   10682 N  N   . LYS D 1 181 ? -38.308 63.914  -12.865 1    113.34 ? 170 LYS D N   1 -0.351 0.586  -0.032 
ATOM   10683 C  CA  . LYS D 1 181 ? -37.056 64.649  -12.717 1    111.95 ? 170 LYS D CA  1 -0.34  0.592  -0.032 
ATOM   10684 C  C   . LYS D 1 181 ? -36.071 63.896  -11.826 1    115.3  ? 170 LYS D C   1 -0.331 0.586  -0.03  
ATOM   10685 O  O   . LYS D 1 181 ? -34.886 63.778  -12.153 1    113.63 ? 170 LYS D O   1 -0.32  0.584  -0.03  
ATOM   10686 C  CB  . LYS D 1 181 ? -37.343 66.044  -12.163 1    116.22 ? 170 LYS D CB  1 -0.342 0.605  -0.03  
ATOM   10687 C  CG  . LYS D 1 181 ? -38.453 66.783  -12.899 1    118.91 ? 170 LYS D CG  1 -0.352 0.612  -0.032 
ATOM   10688 C  CD  . LYS D 1 181 ? -38.767 68.121  -12.239 1    127.48 ? 170 LYS D CD  1 -0.355 0.624  -0.031 
ATOM   10689 C  CE  . LYS D 1 181 ? -37.536 69.027  -12.202 1    132.85 ? 170 LYS D CE  1 -0.344 0.633  -0.03  
ATOM   10690 N  NZ  . LYS D 1 181 ? -37.644 70.097  -11.159 1    122.32 ? 170 LYS D NZ  1 -0.345 0.642  -0.028 
ATOM   10691 N  N   . ALA D 1 182 ? -36.55  63.378  -10.694 1    116.85 ? 171 ALA D N   1 -0.335 0.581  -0.027 
ATOM   10692 C  CA  . ALA D 1 182 ? -35.759 62.526  -9.815  1    114.14 ? 171 ALA D CA  1 -0.328 0.573  -0.025 
ATOM   10693 C  C   . ALA D 1 182 ? -36.229 61.086  -9.993  1    111.04 ? 171 ALA D C   1 -0.332 0.56   -0.025 
ATOM   10694 O  O   . ALA D 1 182 ? -37.386 60.759  -9.694  1    109.54 ? 171 ALA D O   1 -0.343 0.557  -0.024 
ATOM   10695 C  CB  . ALA D 1 182 ? -35.891 62.973  -8.358  1    117.9  ? 171 ALA D CB  1 -0.329 0.577  -0.021 
ATOM   10696 N  N   . HIS D 1 183 ? -35.33  60.23   -10.475 1    105.75 ? 172 HIS D N   1 -0.324 0.552  -0.026 
ATOM   10697 C  CA  . HIS D 1 183 ? -35.692 58.901  -10.961 1    107.78 ? 172 HIS D CA  1 -0.327 0.54   -0.027 
ATOM   10698 C  C   . HIS D 1 183 ? -34.849 57.845  -10.263 1    101.64 ? 172 HIS D C   1 -0.319 0.53   -0.026 
ATOM   10699 O  O   . HIS D 1 183 ? -33.63  57.79   -10.468 1    99.8   ? 172 HIS D O   1 -0.308 0.53   -0.026 
ATOM   10700 C  CB  . HIS D 1 183 ? -35.493 58.81   -12.479 1    117.88 ? 172 HIS D CB  1 -0.325 0.539  -0.031 
ATOM   10701 C  CG  . HIS D 1 183 ? -36.547 58.011  -13.176 1    112.8  ? 172 HIS D CG  1 -0.335 0.532  -0.033 
ATOM   10702 N  ND1 . HIS D 1 183 ? -36.68  56.648  -13.01  1    108.48 ? 172 HIS D ND1 1 -0.336 0.519  -0.032 
ATOM   10703 C  CD2 . HIS D 1 183 ? -37.529 58.387  -14.029 1    120.14 ? 172 HIS D CD2 1 -0.344 0.535  -0.035 
ATOM   10704 C  CE1 . HIS D 1 183 ? -37.7   56.217  -13.733 1    114.56 ? 172 HIS D CE1 1 -0.345 0.515  -0.034 
ATOM   10705 N  NE2 . HIS D 1 183 ? -38.229 57.252  -14.363 1    122.3  ? 172 HIS D NE2 1 -0.35  0.525  -0.036 
ATOM   10706 N  N   . PHE D 1 184 ? -35.498 56.998  -9.468  1    99.38  ? 173 PHE D N   1 -0.325 0.522  -0.024 
ATOM   10707 C  CA  . PHE D 1 184 ? -34.83  55.9    -8.782  1    102.13 ? 173 PHE D CA  1 -0.319 0.512  -0.022 
ATOM   10708 C  C   . PHE D 1 184 ? -35.393 54.609  -9.346  1    102.08 ? 173 PHE D C   1 -0.324 0.5    -0.023 
ATOM   10709 O  O   . PHE D 1 184 ? -36.609 54.381  -9.291  1    97.28  ? 173 PHE D O   1 -0.335 0.498  -0.023 
ATOM   10710 C  CB  . PHE D 1 184 ? -35.029 55.987  -7.264  1    101.88 ? 173 PHE D CB  1 -0.321 0.513  -0.018 
ATOM   10711 C  CG  . PHE D 1 184 ? -34.468 57.244  -6.665  1    98.93  ? 173 PHE D CG  1 -0.316 0.525  -0.017 
ATOM   10712 C  CD1 . PHE D 1 184 ? -35.222 58.411  -6.65   1    96.71  ? 173 PHE D CD1 1 -0.323 0.535  -0.017 
ATOM   10713 C  CD2 . PHE D 1 184 ? -33.17  57.273  -6.158  1    98.92  ? 173 PHE D CD2 1 -0.304 0.525  -0.015 
ATOM   10714 C  CE1 . PHE D 1 184 ? -34.7   59.578  -6.13   1    100.13 ? 173 PHE D CE1 1 -0.318 0.546  -0.015 
ATOM   10715 C  CE2 . PHE D 1 184 ? -32.641 58.439  -5.628  1    97.08  ? 173 PHE D CE2 1 -0.299 0.536  -0.014 
ATOM   10716 C  CZ  . PHE D 1 184 ? -33.41  59.59   -5.608  1    96.8   ? 173 PHE D CZ  1 -0.306 0.546  -0.014 
ATOM   10717 N  N   . SER D 1 185 ? -34.514 53.78   -9.908  1    103.04 ? 174 SER D N   1 -0.316 0.493  -0.025 
ATOM   10718 C  CA  . SER D 1 185 ? -34.931 52.6    -10.656 1    107.18 ? 174 SER D CA  1 -0.32  0.482  -0.027 
ATOM   10719 C  C   . SER D 1 185 ? -34.178 51.373  -10.157 1    96.48  ? 174 SER D C   1 -0.313 0.471  -0.025 
ATOM   10720 O  O   . SER D 1 185 ? -32.958 51.423  -9.949  1    93.44  ? 174 SER D O   1 -0.302 0.471  -0.025 
ATOM   10721 C  CB  . SER D 1 185 ? -34.726 52.825  -12.168 1    104.11 ? 174 SER D CB  1 -0.318 0.484  -0.03  
ATOM   10722 O  OG  . SER D 1 185 ? -34.581 51.598  -12.854 1    108.64 ? 174 SER D OG  1 -0.317 0.473  -0.032 
ATOM   10723 N  N   . PHE D 1 186 ? -34.917 50.28   -9.96   1    91.04  ? 175 PHE D N   1 -0.32  0.461  -0.025 
ATOM   10724 C  CA  . PHE D 1 186 ? -34.397 49.046  -9.372  1    98.79  ? 175 PHE D CA  1 -0.315 0.449  -0.023 
ATOM   10725 C  C   . PHE D 1 186 ? -34.566 47.942  -10.403 1    96.8   ? 175 PHE D C   1 -0.317 0.439  -0.026 
ATOM   10726 O  O   . PHE D 1 186 ? -35.653 47.375  -10.54  1    95.13  ? 175 PHE D O   1 -0.327 0.434  -0.026 
ATOM   10727 C  CB  . PHE D 1 186 ? -35.104 48.712  -8.044  1    97.02  ? 175 PHE D CB  1 -0.322 0.446  -0.02  
ATOM   10728 C  CG  . PHE D 1 186 ? -34.849 49.734  -6.986  1    95.01  ? 175 PHE D CG  1 -0.319 0.456  -0.017 
ATOM   10729 C  CD1 . PHE D 1 186 ? -35.649 50.857  -6.885  1    98.9   ? 175 PHE D CD1 1 -0.327 0.466  -0.017 
ATOM   10730 C  CD2 . PHE D 1 186 ? -33.744 49.637  -6.164  1    91.85  ? 175 PHE D CD2 1 -0.309 0.455  -0.015 
ATOM   10731 C  CE1 . PHE D 1 186 ? -35.369 51.845  -5.952  1    97.41  ? 175 PHE D CE1 1 -0.324 0.475  -0.015 
ATOM   10732 C  CE2 . PHE D 1 186 ? -33.464 50.606  -5.235  1    91.43  ? 175 PHE D CE2 1 -0.307 0.464  -0.013 
ATOM   10733 C  CZ  . PHE D 1 186 ? -34.279 51.712  -5.128  1    99.24  ? 175 PHE D CZ  1 -0.314 0.474  -0.013 
ATOM   10734 N  N   . GLY D 1 187 ? -33.493 47.653  -11.131 1    90.74  ? 176 GLY D N   1 -0.307 0.437  -0.028 
ATOM   10735 C  CA  . GLY D 1 187 ? -33.522 46.549  -12.062 1    100.76 ? 176 GLY D CA  1 -0.307 0.427  -0.03  
ATOM   10736 C  C   . GLY D 1 187 ? -32.203 45.812  -12.143 1    103.43 ? 176 GLY D C   1 -0.295 0.42   -0.03  
ATOM   10737 O  O   . GLY D 1 187 ? -31.412 45.824  -11.184 1    91.36  ? 176 GLY D O   1 -0.288 0.42   -0.028 
ATOM   10738 N  N   . LEU D 1 188 ? -31.956 45.144  -13.319 1    96.64  ? 177 LEU D N   1 -0.293 0.414  -0.033 
ATOM   10739 C  CA  . LEU D 1 188 ? -30.697 44.442  -13.467 1    90.09  ? 177 LEU D CA  1 -0.281 0.407  -0.034 
ATOM   10740 C  C   . LEU D 1 188 ? -29.579 45.449  -13.71  1    88.65  ? 177 LEU D C   1 -0.271 0.417  -0.034 
ATOM   10741 O  O   . LEU D 1 188 ? -29.83  46.549  -14.209 1    89.7   ? 177 LEU D O   1 -0.273 0.427  -0.035 
ATOM   10742 C  CB  . LEU D 1 188 ? -30.759 43.464  -14.624 1    96.59  ? 177 LEU D CB  1 -0.282 0.398  -0.037 
ATOM   10743 C  CG  . LEU D 1 188 ? -31.93  42.52   -14.468 1    97.24  ? 177 LEU D CG  1 -0.293 0.39   -0.036 
ATOM   10744 C  CD1 . LEU D 1 188 ? -33.108 43.029  -15.287 1    105.86 ? 177 LEU D CD1 1 -0.303 0.394  -0.038 
ATOM   10745 C  CD2 . LEU D 1 188 ? -31.57  41.083  -14.844 1    97.73  ? 177 LEU D CD2 1 -0.289 0.376  -0.037 
ATOM   10746 N  N   . PRO D 1 189 ? -28.332 45.094  -13.382 1    82.2   ? 178 PRO D N   1 -0.26  0.413  -0.033 
ATOM   10747 C  CA  . PRO D 1 189 ? -27.262 46.107  -13.433 1    90.92  ? 178 PRO D CA  1 -0.25  0.423  -0.034 
ATOM   10748 C  C   . PRO D 1 189 ? -26.859 46.502  -14.85  1    100.19 ? 178 PRO D C   1 -0.246 0.426  -0.037 
ATOM   10749 O  O   . PRO D 1 189 ? -27.437 46.041  -15.845 1    98.46  ? 178 PRO D O   1 -0.251 0.422  -0.04  
ATOM   10750 C  CB  . PRO D 1 189 ? -26.11  45.446  -12.667 1    90.46  ? 178 PRO D CB  1 -0.239 0.416  -0.032 
ATOM   10751 C  CG  . PRO D 1 189 ? -26.364 43.981  -12.753 1    87     ? 178 PRO D CG  1 -0.242 0.403  -0.032 
ATOM   10752 C  CD  . PRO D 1 189 ? -27.852 43.789  -12.888 1    80.01  ? 178 PRO D CD  1 -0.255 0.401  -0.032 
ATOM   10753 N  N   . SER D 1 190 ? -25.882 47.392  -14.95  1    101.09 ? 179 SER D N   1 -0.237 0.434  -0.037 
ATOM   10754 C  CA  . SER D 1 190 ? -25.595 48.016  -16.228 1    98.07  ? 179 SER D CA  1 -0.235 0.44   -0.041 
ATOM   10755 C  C   . SER D 1 190 ? -24.114 48.302  -16.378 1    104.85 ? 179 SER D C   1 -0.221 0.443  -0.041 
ATOM   10756 O  O   . SER D 1 190 ? -23.538 48.03   -17.437 1    111.12 ? 179 SER D O   1 -0.216 0.44   -0.044 
ATOM   10757 C  CB  . SER D 1 190 ? -26.367 49.33   -16.399 1    97     ? 179 SER D CB  1 -0.242 0.452  -0.041 
ATOM   10758 O  OG  . SER D 1 190 ? -25.653 50.441  -15.865 1    99.4   ? 179 SER D OG  1 -0.235 0.462  -0.04  
ATOM   10759 N  N   . HIS D 1 191 ? -23.493 48.851  -15.336 1    101.23 ? 180 HIS D N   1 -0.215 0.448  -0.038 
ATOM   10760 C  CA  . HIS D 1 191 ? -22.182 49.484  -15.486 1    104.72 ? 180 HIS D CA  1 -0.203 0.453  -0.039 
ATOM   10761 C  C   . HIS D 1 191 ? -21.078 48.508  -15.937 1    106    ? 180 HIS D C   1 -0.193 0.445  -0.04  
ATOM   10762 O  O   . HIS D 1 191 ? -19.934 48.943  -16.107 1    105.35 ? 180 HIS D O   1 -0.183 0.449  -0.04  
ATOM   10763 C  CB  . HIS D 1 191 ? -21.815 50.2    -14.166 1    109.24 ? 180 HIS D CB  1 -0.2   0.46   -0.035 
ATOM   10764 C  CG  . HIS D 1 191 ? -21.34  49.287  -13.075 1    103.06 ? 180 HIS D CG  1 -0.196 0.452  -0.033 
ATOM   10765 N  ND1 . HIS D 1 191 ? -20.217 49.554  -12.319 1    98     ? 180 HIS D ND1 1 -0.185 0.454  -0.031 
ATOM   10766 C  CD2 . HIS D 1 191 ? -21.808 48.093  -12.642 1    100.51 ? 180 HIS D CD2 1 -0.2   0.441  -0.032 
ATOM   10767 C  CE1 . HIS D 1 191 ? -20.015 48.562  -11.47  1    102.85 ? 180 HIS D CE1 1 -0.183 0.445  -0.029 
ATOM   10768 N  NE2 . HIS D 1 191 ? -20.969 47.665  -11.642 1    100.52 ? 180 HIS D NE2 1 -0.192 0.437  -0.029 
ATOM   10769 N  N   . HIS D 1 192 ? -21.378 47.219  -16.139 1    106.29 ? 181 HIS D N   1 -0.196 0.433  -0.04  
ATOM   10770 C  CA  . HIS D 1 192 ? -20.402 46.256  -16.642 1    111.02 ? 181 HIS D CA  1 -0.187 0.424  -0.042 
ATOM   10771 C  C   . HIS D 1 192 ? -20.628 45.85   -18.1   1    114.69 ? 181 HIS D C   1 -0.189 0.42   -0.045 
ATOM   10772 O  O   . HIS D 1 192 ? -19.723 45.269  -18.716 1    113.52 ? 181 HIS D O   1 -0.181 0.415  -0.047 
ATOM   10773 C  CB  . HIS D 1 192 ? -20.394 44.985  -15.78  1    109.87 ? 181 HIS D CB  1 -0.187 0.412  -0.039 
ATOM   10774 C  CG  . HIS D 1 192 ? -19.571 45.086  -14.533 1    113.07 ? 181 HIS D CG  1 -0.179 0.413  -0.036 
ATOM   10775 N  ND1 . HIS D 1 192 ? -18.565 46.016  -14.38  1    113.66 ? 181 HIS D ND1 1 -0.17  0.422  -0.036 
ATOM   10776 C  CD2 . HIS D 1 192 ? -19.594 44.361  -13.383 1    112.18 ? 181 HIS D CD2 1 -0.18  0.407  -0.033 
ATOM   10777 C  CE1 . HIS D 1 192 ? -18.009 45.867  -13.188 1    111.75 ? 181 HIS D CE1 1 -0.165 0.42   -0.033 
ATOM   10778 N  NE2 . HIS D 1 192 ? -18.613 44.869  -12.563 1    110.54 ? 181 HIS D NE2 1 -0.171 0.411  -0.031 
ATOM   10779 N  N   . ALA D 1 193 ? -21.795 46.138  -18.669 1    111.72 ? 182 ALA D N   1 -0.2   0.423  -0.047 
ATOM   10780 C  CA  . ALA D 1 193 ? -22.034 45.819  -20.072 1    112.17 ? 182 ALA D CA  1 -0.202 0.42   -0.05  
ATOM   10781 C  C   . ALA D 1 193 ? -21.211 46.736  -20.976 1    112.74 ? 182 ALA D C   1 -0.194 0.428  -0.052 
ATOM   10782 O  O   . ALA D 1 193 ? -21.398 47.96   -20.969 1    104.13 ? 182 ALA D O   1 -0.196 0.44   -0.052 
ATOM   10783 C  CB  . ALA D 1 193 ? -23.522 45.936  -20.394 1    105.72 ? 182 ALA D CB  1 -0.216 0.421  -0.051 
ATOM   10784 N  N   . TYR D 1 194 ? -20.291 46.139  -21.741 1    118.97 ? 183 TYR D N   1 -0.186 0.423  -0.054 
ATOM   10785 C  CA  . TYR D 1 194 ? -19.63  46.791  -22.869 1    116.15 ? 183 TYR D CA  1 -0.18  0.429  -0.057 
ATOM   10786 C  C   . TYR D 1 194 ? -20.528 46.784  -24.112 1    112.38 ? 183 TYR D C   1 -0.188 0.429  -0.06  
ATOM   10787 O  O   . TYR D 1 194 ? -21.504 46.034  -24.216 1    110.45 ? 183 TYR D O   1 -0.197 0.422  -0.06  
ATOM   10788 C  CB  . TYR D 1 194 ? -18.332 46.082  -23.235 1    114.51 ? 183 TYR D CB  1 -0.168 0.422  -0.058 
ATOM   10789 C  CG  . TYR D 1 194 ? -17.169 46.209  -22.302 1    110.51 ? 183 TYR D CG  1 -0.157 0.423  -0.056 
ATOM   10790 C  CD1 . TYR D 1 194 ? -16.308 47.284  -22.403 1    112.16 ? 183 TYR D CD1 1 -0.149 0.433  -0.056 
ATOM   10791 C  CD2 . TYR D 1 194 ? -16.869 45.208  -21.39  1    115.62 ? 183 TYR D CD2 1 -0.155 0.414  -0.053 
ATOM   10792 C  CE1 . TYR D 1 194 ? -15.207 47.394  -21.59  1    114.96 ? 183 TYR D CE1 1 -0.139 0.434  -0.054 
ATOM   10793 C  CE2 . TYR D 1 194 ? -15.762 45.305  -20.567 1    116.15 ? 183 TYR D CE2 1 -0.144 0.415  -0.051 
ATOM   10794 C  CZ  . TYR D 1 194 ? -14.935 46.406  -20.675 1    114.6  ? 183 TYR D CZ  1 -0.137 0.425  -0.052 
ATOM   10795 O  OH  . TYR D 1 194 ? -13.828 46.529  -19.871 1    119.56 ? 183 TYR D OH  1 -0.127 0.426  -0.05  
ATOM   10796 N  N   . THR D 1 195 ? -20.14  47.595  -25.096 1    114.35 ? 184 THR D N   1 -0.185 0.436  -0.063 
ATOM   10797 C  CA  . THR D 1 195 ? -20.927 47.706  -26.324 1    120.26 ? 184 THR D CA  1 -0.192 0.437  -0.066 
ATOM   10798 C  C   . THR D 1 195 ? -20.866 46.434  -27.184 1    117.37 ? 184 THR D C   1 -0.191 0.426  -0.068 
ATOM   10799 O  O   . THR D 1 195 ? -21.815 46.146  -27.923 1    109.71 ? 184 THR D O   1 -0.2   0.423  -0.07  
ATOM   10800 C  CB  . THR D 1 195 ? -20.454 48.93   -27.117 1    114.6  ? 184 THR D CB  1 -0.187 0.448  -0.068 
ATOM   10801 O  OG1 . THR D 1 195 ? -21.411 49.23   -28.131 1    115.57 ? 184 THR D OG1 1 -0.196 0.451  -0.07  
ATOM   10802 C  CG2 . THR D 1 195 ? -19.088 48.681  -27.755 1    113.07 ? 184 THR D CG2 1 -0.175 0.446  -0.069 
ATOM   10803 N  N   . GLN D 1 196 ? -19.786 45.65   -27.086 1    121.17 ? 185 GLN D N   1 -0.181 0.418  -0.068 
ATOM   10804 C  CA  . GLN D 1 196 ? -19.635 44.411  -27.846 1    120.92 ? 185 GLN D CA  1 -0.18  0.407  -0.07  
ATOM   10805 C  C   . GLN D 1 196 ? -19.787 43.139  -27.012 1    123.32 ? 185 GLN D C   1 -0.181 0.395  -0.067 
ATOM   10806 O  O   . GLN D 1 196 ? -20.278 42.14   -27.529 1    125.67 ? 185 GLN D O   1 -0.186 0.386  -0.069 
ATOM   10807 C  CB  . GLN D 1 196 ? -18.275 44.394  -28.567 1    127.54 ? 185 GLN D CB  1 -0.167 0.407  -0.071 
ATOM   10808 C  CG  . GLN D 1 196 ? -17.964 43.098  -29.352 1    132.4  ? 185 GLN D CG  1 -0.165 0.395  -0.073 
ATOM   10809 C  CD  . GLN D 1 196 ? -17.713 43.307  -30.859 1    139.7  ? 185 GLN D CD  1 -0.162 0.397  -0.077 
ATOM   10810 O  OE1 . GLN D 1 196 ? -18.08  44.34   -31.442 1    132.14 ? 185 GLN D OE1 1 -0.166 0.406  -0.079 
ATOM   10811 N  NE2 . GLN D 1 196 ? -17.091 42.309  -31.49  1    138.26 ? 185 GLN D NE2 1 -0.157 0.388  -0.079 
ATOM   10812 N  N   A MET D 1 197 ? -19.338 43.143  -25.763 0.45 121.39 ? 186 MET D N   1 -0.177 0.395  -0.064 
ATOM   10813 N  N   B MET D 1 197 ? -19.406 43.125  -25.733 0.55 121.22 ? 186 MET D N   1 -0.178 0.395  -0.064 
ATOM   10814 C  CA  A MET D 1 197 ? -19.605 42.057  -24.839 0.45 122.08 ? 186 MET D CA  1 -0.18  0.385  -0.062 
ATOM   10815 C  CA  B MET D 1 197 ? -19.689 41.949  -24.914 0.55 122.1  ? 186 MET D CA  1 -0.18  0.384  -0.062 
ATOM   10816 C  C   A MET D 1 197 ? -20.321 42.623  -23.623 0.45 120.98 ? 186 MET D C   1 -0.186 0.391  -0.059 
ATOM   10817 C  C   B MET D 1 197 ? -20.035 42.344  -23.486 0.55 121.3  ? 186 MET D C   1 -0.184 0.388  -0.059 
ATOM   10818 O  O   A MET D 1 197 ? -20.151 43.79   -23.275 0.45 118.85 ? 186 MET D O   1 -0.185 0.401  -0.058 
ATOM   10819 O  O   B MET D 1 197 ? -19.291 43.09   -22.84  0.55 120.28 ? 186 MET D O   1 -0.177 0.395  -0.057 
ATOM   10820 C  CB  A MET D 1 197 ? -18.314 41.324  -24.401 0.45 122.53 ? 186 MET D CB  1 -0.168 0.379  -0.061 
ATOM   10821 C  CB  B MET D 1 197 ? -18.525 40.945  -24.909 0.55 123.23 ? 186 MET D CB  1 -0.17  0.375  -0.062 
ATOM   10822 C  CG  A MET D 1 197 ? -17.335 42.137  -23.546 0.45 117.43 ? 186 MET D CG  1 -0.159 0.386  -0.059 
ATOM   10823 C  CG  B MET D 1 197 ? -18.841 39.631  -24.162 0.55 119.2  ? 186 MET D CG  1 -0.173 0.363  -0.06  
ATOM   10824 S  SD  A MET D 1 197 ? -16.144 41.077  -22.691 0.45 112.82 ? 186 MET D SD  1 -0.148 0.376  -0.057 
ATOM   10825 S  SD  B MET D 1 197 ? -20.471 38.93   -24.547 0.55 107.78 ? 186 MET D SD  1 -0.188 0.357  -0.061 
ATOM   10826 C  CE  A MET D 1 197 ? -14.884 42.265  -22.223 0.45 112.03 ? 186 MET D CE  1 -0.136 0.387  -0.055 
ATOM   10827 C  CE  B MET D 1 197 ? -20.393 37.403  -23.603 0.55 114.99 ? 186 MET D CE  1 -0.187 0.343  -0.059 
ATOM   10828 N  N   . GLY D 1 198 ? -21.156 41.812  -22.995 1    122.01 ? 187 GLY D N   1 -0.194 0.383  -0.057 
ATOM   10829 C  CA  . GLY D 1 198 ? -21.579 42.064  -21.64  1    116.68 ? 187 GLY D CA  1 -0.198 0.385  -0.054 
ATOM   10830 C  C   . GLY D 1 198 ? -20.734 41.266  -20.667 1    122.67 ? 187 GLY D C   1 -0.19  0.378  -0.052 
ATOM   10831 O  O   . GLY D 1 198 ? -20.206 40.202  -20.994 1    123.92 ? 187 GLY D O   1 -0.185 0.368  -0.052 
ATOM   10832 N  N   . SER D 1 199 ? -20.593 41.79   -19.455 1    121.5  ? 188 SER D N   1 -0.189 0.383  -0.049 
ATOM   10833 C  CA  . SER D 1 199 ? -19.752 41.14   -18.469 1    119.98 ? 188 SER D CA  1 -0.181 0.377  -0.046 
ATOM   10834 C  C   . SER D 1 199 ? -20.377 41.335  -17.103 1    118.52 ? 188 SER D C   1 -0.187 0.379  -0.043 
ATOM   10835 O  O   . SER D 1 199 ? -21.299 42.141  -16.933 1    113.02 ? 188 SER D O   1 -0.195 0.386  -0.042 
ATOM   10836 C  CB  . SER D 1 199 ? -18.328 41.696  -18.509 1    122.4  ? 188 SER D CB  1 -0.168 0.382  -0.046 
ATOM   10837 O  OG  . SER D 1 199 ? -18.328 43.094  -18.261 1    121.14 ? 188 SER D OG  1 -0.168 0.395  -0.046 
ATOM   10838 N  N   . GLY D 1 200 ? -19.856 40.57   -16.132 1    123.22 ? 189 GLY D N   1 -0.182 0.372  -0.04  
ATOM   10839 C  CA  . GLY D 1 200 ? -20.172 40.687  -14.718 1    115.23 ? 189 GLY D CA  1 -0.185 0.373  -0.037 
ATOM   10840 C  C   . GLY D 1 200 ? -21.6   41.076  -14.411 1    110.56 ? 189 GLY D C   1 -0.198 0.376  -0.036 
ATOM   10841 O  O   . GLY D 1 200 ? -21.878 42.203  -13.99  1    108.37 ? 189 GLY D O   1 -0.2   0.387  -0.035 
ATOM   10842 N  N   . PHE D 1 201 ? -22.519 40.142  -14.622 1    110.22 ? 190 PHE D N   1 -0.206 0.368  -0.037 
ATOM   10843 C  CA  . PHE D 1 201 ? -23.927 40.244  -14.277 1    105.71 ? 190 PHE D CA  1 -0.219 0.369  -0.036 
ATOM   10844 C  C   . PHE D 1 201 ? -24.694 41.277  -15.105 1    106.61 ? 190 PHE D C   1 -0.226 0.378  -0.038 
ATOM   10845 O  O   . PHE D 1 201 ? -25.9   41.42   -14.89  1    105    ? 190 PHE D O   1 -0.237 0.38   -0.037 
ATOM   10846 C  CB  . PHE D 1 201 ? -24.141 40.571  -12.794 1    113.83 ? 190 PHE D CB  1 -0.221 0.372  -0.032 
ATOM   10847 C  CG  . PHE D 1 201 ? -23.258 39.79   -11.836 1    118.77 ? 190 PHE D CG  1 -0.213 0.365  -0.03  
ATOM   10848 C  CD1 . PHE D 1 201 ? -22.016 40.311  -11.415 1    123.73 ? 190 PHE D CD1 1 -0.202 0.369  -0.029 
ATOM   10849 C  CD2 . PHE D 1 201 ? -23.706 38.561  -11.301 1    113.47 ? 190 PHE D CD2 1 -0.217 0.353  -0.028 
ATOM   10850 C  CE1 . PHE D 1 201 ? -21.22  39.614  -10.518 1    109.85 ? 190 PHE D CE1 1 -0.194 0.363  -0.026 
ATOM   10851 C  CE2 . PHE D 1 201 ? -22.926 37.826  -10.407 1    121.68 ? 190 PHE D CE2 1 -0.21  0.347  -0.026 
ATOM   10852 C  CZ  . PHE D 1 201 ? -21.666 38.38   -9.99   1    114.36 ? 190 PHE D CZ  1 -0.199 0.352  -0.025 
ATOM   10853 N  N   . CYS D 1 202 ? -24.066 41.974  -16.055 1    109.24 ? 191 CYS D N   1 -0.221 0.385  -0.04  
ATOM   10854 C  CA  . CYS D 1 202 ? -24.698 43.069  -16.786 1    110.65 ? 191 CYS D CA  1 -0.226 0.395  -0.042 
ATOM   10855 C  C   . CYS D 1 202 ? -24.84  42.702  -18.248 1    112.89 ? 191 CYS D C   1 -0.228 0.391  -0.046 
ATOM   10856 O  O   . CYS D 1 202 ? -23.849 42.336  -18.888 1    117.55 ? 191 CYS D O   1 -0.219 0.388  -0.047 
ATOM   10857 C  CB  . CYS D 1 202 ? -23.884 44.355  -16.71  1    113.62 ? 191 CYS D CB  1 -0.219 0.406  -0.042 
ATOM   10858 S  SG  . CYS D 1 202 ? -23.542 44.938  -15.043 1    104.8  ? 191 CYS D SG  1 -0.216 0.412  -0.038 
ATOM   10859 N  N   . LEU D 1 203 ? -26.058 42.825  -18.774 1    109.93 ? 192 LEU D N   1 -0.239 0.392  -0.047 
ATOM   10860 C  CA  . LEU D 1 203 ? -26.358 42.513  -20.165 1    108.1  ? 192 LEU D CA  1 -0.242 0.39   -0.05  
ATOM   10861 C  C   . LEU D 1 203 ? -26.317 43.746  -21.061 1    111.24 ? 192 LEU D C   1 -0.241 0.401  -0.053 
ATOM   10862 O  O   . LEU D 1 203 ? -25.589 43.76   -22.056 1    116.43 ? 192 LEU D O   1 -0.235 0.401  -0.055 
ATOM   10863 C  CB  . LEU D 1 203 ? -27.721 41.818  -20.265 1    103.18 ? 192 LEU D CB  1 -0.254 0.383  -0.051 
ATOM   10864 C  CG  . LEU D 1 203 ? -27.751 40.421  -19.641 1    104.18 ? 192 LEU D CG  1 -0.254 0.37   -0.049 
ATOM   10865 C  CD1 . LEU D 1 203 ? -29.118 39.78   -19.754 1    100.93 ? 192 LEU D CD1 1 -0.267 0.365  -0.049 
ATOM   10866 C  CD2 . LEU D 1 203 ? -26.693 39.516  -20.264 1    101.88 ? 192 LEU D CD2 1 -0.245 0.362  -0.051 
ATOM   10867 N  N   . ILE D 1 204 ? -27.084 44.79   -20.737 1    110.26 ? 193 ILE D N   1 -0.248 0.41   -0.052 
ATOM   10868 C  CA  . ILE D 1 204 ? -26.997 46.067  -21.434 1    106.28 ? 193 ILE D CA  1 -0.247 0.422  -0.054 
ATOM   10869 C  C   . ILE D 1 204 ? -26.727 47.187  -20.433 1    112.68 ? 193 ILE D C   1 -0.245 0.432  -0.051 
ATOM   10870 O  O   . ILE D 1 204 ? -26.955 47.055  -19.226 1    112.46 ? 193 ILE D O   1 -0.247 0.431  -0.048 
ATOM   10871 C  CB  . ILE D 1 204 ? -28.263 46.387  -22.253 1    108.18 ? 193 ILE D CB  1 -0.259 0.425  -0.056 
ATOM   10872 C  CG1 . ILE D 1 204 ? -29.521 46.089  -21.447 1    103.05 ? 193 ILE D CG1 1 -0.271 0.422  -0.054 
ATOM   10873 C  CG2 . ILE D 1 204 ? -28.259 45.624  -23.581 1    110.16 ? 193 ILE D CG2 1 -0.259 0.418  -0.059 
ATOM   10874 C  CD1 . ILE D 1 204 ? -30.788 46.307  -22.235 1    100.64 ? 193 ILE D CD1 1 -0.282 0.424  -0.056 
ATOM   10875 N  N   . ASN D 1 205 ? -26.232 48.307  -20.957 1    112.57 ? 194 ASN D N   1 -0.24  0.443  -0.052 
ATOM   10876 C  CA  . ASN D 1 205 ? -25.786 49.448  -20.158 1    106.48 ? 194 ASN D CA  1 -0.236 0.453  -0.05  
ATOM   10877 C  C   . ASN D 1 205 ? -26.853 50.534  -20.269 1    107.72 ? 194 ASN D C   1 -0.246 0.463  -0.051 
ATOM   10878 O  O   . ASN D 1 205 ? -26.761 51.428  -21.116 1    103.85 ? 194 ASN D O   1 -0.245 0.471  -0.053 
ATOM   10879 C  CB  . ASN D 1 205 ? -24.428 49.933  -20.645 1    107.34 ? 194 ASN D CB  1 -0.224 0.458  -0.052 
ATOM   10880 C  CG  . ASN D 1 205 ? -23.794 50.938  -19.713 1    107.41 ? 194 ASN D CG  1 -0.218 0.467  -0.049 
ATOM   10881 O  OD1 . ASN D 1 205 ? -24.455 51.846  -19.208 1    108.28 ? 194 ASN D OD1 1 -0.224 0.475  -0.048 
ATOM   10882 N  ND2 . ASN D 1 205 ? -22.5   50.782  -19.477 1    106.75 ? 194 ASN D ND2 1 -0.206 0.465  -0.049 
ATOM   10883 N  N   . LYS D 1 206 ? -27.865 50.447  -19.39  1    107.74 ? 195 LYS D N   1 -0.255 0.462  -0.048 
ATOM   10884 C  CA  . LYS D 1 206 ? -29.042 51.311  -19.472 1    104.88 ? 195 LYS D CA  1 -0.266 0.47   -0.049 
ATOM   10885 C  C   . LYS D 1 206 ? -28.712 52.77   -19.176 1    103.01 ? 195 LYS D C   1 -0.263 0.484  -0.048 
ATOM   10886 O  O   . LYS D 1 206 ? -29.411 53.667  -19.664 1    100.92 ? 195 LYS D O   1 -0.27  0.492  -0.049 
ATOM   10887 C  CB  . LYS D 1 206 ? -30.129 50.793  -18.527 1    99.87  ? 195 LYS D CB  1 -0.276 0.465  -0.046 
ATOM   10888 C  CG  . LYS D 1 206 ? -31.344 51.696  -18.387 1    105.44 ? 195 LYS D CG  1 -0.287 0.474  -0.046 
ATOM   10889 C  CD  . LYS D 1 206 ? -32.172 51.333  -17.166 1    107.53 ? 195 LYS D CD  1 -0.295 0.47   -0.043 
ATOM   10890 C  CE  . LYS D 1 206 ? -33.062 52.493  -16.725 1    109.11 ? 195 LYS D CE  1 -0.303 0.481  -0.042 
ATOM   10891 N  NZ  . LYS D 1 206 ? -33.668 52.235  -15.378 1    106.66 ? 195 LYS D NZ  1 -0.309 0.479  -0.038 
ATOM   10892 N  N   . THR D 1 207 ? -27.651 53.027  -18.409 1    109.37 ? 196 THR D N   1 -0.253 0.486  -0.046 
ATOM   10893 C  CA  . THR D 1 207 ? -27.236 54.4    -18.13  1    112.35 ? 196 THR D CA  1 -0.25  0.499  -0.045 
ATOM   10894 C  C   . THR D 1 207 ? -26.887 55.132  -19.417 1    107.79 ? 196 THR D C   1 -0.246 0.505  -0.048 
ATOM   10895 O  O   . THR D 1 207 ? -27.413 56.216  -19.7   1    104.56 ? 196 THR D O   1 -0.251 0.515  -0.049 
ATOM   10896 C  CB  . THR D 1 207 ? -26.028 54.415  -17.191 1    103.88 ? 196 THR D CB  1 -0.239 0.499  -0.043 
ATOM   10897 O  OG1 . THR D 1 207 ? -26.197 53.428  -16.172 1    100.47 ? 196 THR D OG1 1 -0.24  0.49   -0.04  
ATOM   10898 C  CG2 . THR D 1 207 ? -25.842 55.794  -16.575 1    95.87  ? 196 THR D CG2 1 -0.237 0.511  -0.041 
ATOM   10899 N  N   . ALA D 1 208 ? -25.974 54.543  -20.197 1    107.49 ? 197 ALA D N   1 -0.238 0.5    -0.05  
ATOM   10900 C  CA  . ALA D 1 208 ? -25.539 55.139  -21.456 1    112.88 ? 197 ALA D CA  1 -0.234 0.505  -0.054 
ATOM   10901 C  C   . ALA D 1 208 ? -26.711 55.446  -22.381 1    108.42 ? 197 ALA D C   1 -0.245 0.508  -0.056 
ATOM   10902 O  O   . ALA D 1 208 ? -26.722 56.481  -23.052 1    109.06 ? 197 ALA D O   1 -0.245 0.518  -0.058 
ATOM   10903 C  CB  . ALA D 1 208 ? -24.532 54.214  -22.142 1    111.14 ? 197 ALA D CB  1 -0.225 0.497  -0.055 
ATOM   10904 N  N   . MET D 1 209 ? -27.715 54.565  -22.426 1    103.17 ? 198 MET D N   1 -0.254 0.5    -0.056 
ATOM   10905 C  CA  . MET D 1 209 ? -28.907 54.869  -23.216 1    109.83 ? 198 MET D CA  1 -0.265 0.503  -0.058 
ATOM   10906 C  C   . MET D 1 209 ? -29.632 56.095  -22.67  1    116.09 ? 198 MET D C   1 -0.272 0.514  -0.057 
ATOM   10907 O  O   . MET D 1 209 ? -29.903 57.048  -23.409 1    121.6  ? 198 MET D O   1 -0.274 0.523  -0.058 
ATOM   10908 C  CB  . MET D 1 209 ? -29.85  53.673  -23.244 1    108.07 ? 198 MET D CB  1 -0.274 0.492  -0.058 
ATOM   10909 C  CG  . MET D 1 209 ? -29.183 52.337  -23.372 1    107.31 ? 198 MET D CG  1 -0.267 0.48   -0.058 
ATOM   10910 S  SD  . MET D 1 209 ? -30.341 51.146  -24.092 1    121.28 ? 198 MET D SD  1 -0.278 0.469  -0.06  
ATOM   10911 C  CE  . MET D 1 209 ? -31.982 51.786  -23.706 1    109.03 ? 198 MET D CE  1 -0.293 0.475  -0.059 
ATOM   10912 N  N   . LEU D 1 210 ? -29.963 56.08   -21.371 1    115.76 ? 199 LEU D N   1 -0.275 0.514  -0.053 
ATOM   10913 C  CA  . LEU D 1 210 ? -30.593 57.237  -20.743 1    115.36 ? 199 LEU D CA  1 -0.28  0.525  -0.052 
ATOM   10914 C  C   . LEU D 1 210 ? -29.818 58.524  -21.011 1    116.53 ? 199 LEU D C   1 -0.273 0.536  -0.052 
ATOM   10915 O  O   . LEU D 1 210 ? -30.419 59.601  -21.108 1    116.63 ? 199 LEU D O   1 -0.279 0.546  -0.053 
ATOM   10916 C  CB  . LEU D 1 210 ? -30.722 57      -19.236 1    113.85 ? 199 LEU D CB  1 -0.282 0.522  -0.048 
ATOM   10917 C  CG  . LEU D 1 210 ? -32.098 56.637  -18.652 1    114.99 ? 199 LEU D CG  1 -0.294 0.519  -0.047 
ATOM   10918 C  CD1 . LEU D 1 210 ? -33.148 57.727  -18.928 1    112.53 ? 199 LEU D CD1 1 -0.304 0.529  -0.047 
ATOM   10919 C  CD2 . LEU D 1 210 ? -32.584 55.286  -19.147 1    117.74 ? 199 LEU D CD2 1 -0.299 0.507  -0.048 
ATOM   10920 N  N   . MET D 1 211 ? -28.489 58.432  -21.14  1    115.07 ? 200 MET D N   1 -0.261 0.535  -0.053 
ATOM   10921 C  CA  . MET D 1 211 ? -27.666 59.596  -21.451 1    117.7  ? 200 MET D CA  1 -0.254 0.546  -0.054 
ATOM   10922 C  C   . MET D 1 211 ? -27.81  60.009  -22.909 1    117.91 ? 200 MET D C   1 -0.255 0.55   -0.057 
ATOM   10923 O  O   . MET D 1 211 ? -28.059 61.183  -23.205 1    116    ? 200 MET D O   1 -0.257 0.561  -0.058 
ATOM   10924 C  CB  . MET D 1 211 ? -26.193 59.314  -21.136 1    121.77 ? 200 MET D CB  1 -0.24  0.544  -0.053 
ATOM   10925 C  CG  . MET D 1 211 ? -25.81  59.414  -19.663 1    113.17 ? 200 MET D CG  1 -0.237 0.544  -0.049 
ATOM   10926 S  SD  . MET D 1 211 ? -24.115 58.877  -19.438 1    128.05 ? 200 MET D SD  1 -0.221 0.54   -0.049 
ATOM   10927 C  CE  . MET D 1 211 ? -23.329 60.175  -20.383 1    123    ? 200 MET D CE  1 -0.214 0.551  -0.051 
ATOM   10928 N  N   . LYS D 1 212 ? -27.619 59.062  -23.835 1    121.61 ? 201 LYS D N   1 -0.253 0.541  -0.06  
ATOM   10929 C  CA  . LYS D 1 212 ? -27.787 59.376  -25.251 1    121.42 ? 201 LYS D CA  1 -0.255 0.544  -0.063 
ATOM   10930 C  C   . LYS D 1 212 ? -29.187 59.905  -25.527 1    122.62 ? 201 LYS D C   1 -0.267 0.549  -0.064 
ATOM   10931 O  O   . LYS D 1 212 ? -29.357 60.877  -26.271 1    127.99 ? 201 LYS D O   1 -0.269 0.558  -0.066 
ATOM   10932 C  CB  . LYS D 1 212 ? -27.495 58.148  -26.116 1    116.56 ? 201 LYS D CB  1 -0.252 0.533  -0.065 
ATOM   10933 C  CG  . LYS D 1 212 ? -27.639 58.385  -27.638 1    128.77 ? 201 LYS D CG  1 -0.253 0.535  -0.069 
ATOM   10934 C  CD  . LYS D 1 212 ? -26.976 59.69   -28.115 1    129.45 ? 201 LYS D CD  1 -0.247 0.547  -0.07  
ATOM   10935 C  CE  . LYS D 1 212 ? -26.114 59.49   -29.354 1    119.87 ? 201 LYS D CE  1 -0.239 0.545  -0.073 
ATOM   10936 N  NZ  . LYS D 1 212 ? -24.713 59.075  -29.003 1    114.61 ? 201 LYS D NZ  1 -0.226 0.541  -0.072 
ATOM   10937 N  N   . GLN D 1 213 ? -30.203 59.287  -24.929 1    116.68 ? 202 GLN D N   1 -0.277 0.543  -0.062 
ATOM   10938 C  CA  . GLN D 1 213 ? -31.543 59.841  -25.04  1    117.25 ? 202 GLN D CA  1 -0.289 0.548  -0.063 
ATOM   10939 C  C   . GLN D 1 213 ? -31.621 61.236  -24.434 1    123.91 ? 202 GLN D C   1 -0.29  0.561  -0.061 
ATOM   10940 O  O   . GLN D 1 213 ? -32.409 62.072  -24.896 1    126.86 ? 202 GLN D O   1 -0.297 0.569  -0.062 
ATOM   10941 C  CB  . GLN D 1 213 ? -32.543 58.897  -24.379 1    118.21 ? 202 GLN D CB  1 -0.298 0.54   -0.061 
ATOM   10942 C  CG  . GLN D 1 213 ? -33.79  59.552  -23.83  1    122.37 ? 202 GLN D CG  1 -0.31  0.546  -0.059 
ATOM   10943 C  CD  . GLN D 1 213 ? -34.665 60.142  -24.902 1    119.24 ? 202 GLN D CD  1 -0.318 0.551  -0.062 
ATOM   10944 O  OE1 . GLN D 1 213 ? -34.303 60.166  -26.072 1    123.63 ? 202 GLN D OE1 1 -0.314 0.551  -0.065 
ATOM   10945 N  NE2 . GLN D 1 213 ? -35.83  60.633  -24.503 1    123.35 ? 202 GLN D NE2 1 -0.328 0.556  -0.061 
ATOM   10946 N  N   . ALA D 1 214 ? -30.784 61.522  -23.431 1    122.08 ? 203 ALA D N   1 -0.282 0.564  -0.059 
ATOM   10947 C  CA  . ALA D 1 214 ? -30.864 62.813  -22.756 1    123.18 ? 203 ALA D CA  1 -0.283 0.576  -0.057 
ATOM   10948 C  C   . ALA D 1 214 ? -30.395 63.947  -23.655 1    126.27 ? 203 ALA D C   1 -0.279 0.586  -0.059 
ATOM   10949 O  O   . ALA D 1 214 ? -30.976 65.04   -23.62  1    129.4  ? 203 ALA D O   1 -0.284 0.596  -0.059 
ATOM   10950 C  CB  . ALA D 1 214 ? -30.06  62.79   -21.454 1    124.66 ? 203 ALA D CB  1 -0.275 0.575  -0.054 
ATOM   10951 N  N   . GLU D 1 215 ? -29.335 63.726  -24.449 1    129.06 ? 204 GLU D N   1 -0.269 0.584  -0.061 
ATOM   10952 C  CA  . GLU D 1 215 ? -28.969 64.725  -25.459 1    134.46 ? 204 GLU D CA  1 -0.265 0.593  -0.064 
ATOM   10953 C  C   . GLU D 1 215 ? -30.048 64.85   -26.519 1    134.22 ? 204 GLU D C   1 -0.275 0.594  -0.066 
ATOM   10954 O  O   . GLU D 1 215 ? -30.22  65.92   -27.11  1    137.98 ? 204 GLU D O   1 -0.277 0.604  -0.068 
ATOM   10955 C  CB  . GLU D 1 215 ? -27.626 64.392  -26.14  1    126.28 ? 204 GLU D CB  1 -0.253 0.59   -0.065 
ATOM   10956 C  CG  . GLU D 1 215 ? -27.654 63.234  -27.174 1    129.48 ? 204 GLU D CG  1 -0.253 0.579  -0.068 
ATOM   10957 C  CD  . GLU D 1 215 ? -28.255 63.601  -28.56  1    140.97 ? 204 GLU D CD  1 -0.259 0.583  -0.071 
ATOM   10958 O  OE1 . GLU D 1 215 ? -28.263 64.811  -28.9   1    147.09 ? 204 GLU D OE1 1 -0.259 0.594  -0.072 
ATOM   10959 O  OE2 . GLU D 1 215 ? -28.723 62.682  -29.295 1    132.22 ? 204 GLU D OE2 1 -0.263 0.574  -0.073 
ATOM   10960 N  N   . LEU D 1 216 ? -30.794 63.772  -26.751 1    132.95 ? 205 LEU D N   1 -0.282 0.584  -0.067 
ATOM   10961 C  CA  . LEU D 1 216 ? -31.649 63.679  -27.924 1    134.03 ? 205 LEU D CA  1 -0.29  0.584  -0.07  
ATOM   10962 C  C   . LEU D 1 216 ? -32.877 64.581  -27.846 1    135.22 ? 205 LEU D C   1 -0.301 0.592  -0.07  
ATOM   10963 O  O   . LEU D 1 216 ? -33.467 64.888  -28.891 1    131.08 ? 205 LEU D O   1 -0.307 0.595  -0.072 
ATOM   10964 C  CB  . LEU D 1 216 ? -32.071 62.222  -28.104 1    137.45 ? 205 LEU D CB  1 -0.294 0.57   -0.07  
ATOM   10965 C  CG  . LEU D 1 216 ? -31.998 61.565  -29.486 1    132.37 ? 205 LEU D CG  1 -0.293 0.564  -0.074 
ATOM   10966 C  CD1 . LEU D 1 216 ? -31.84  62.607  -30.55  1    130.12 ? 205 LEU D CD1 1 -0.292 0.574  -0.076 
ATOM   10967 C  CD2 . LEU D 1 216 ? -30.91  60.486  -29.585 1    127.51 ? 205 LEU D CD2 1 -0.283 0.554  -0.074 
ATOM   10968 N  N   . SER D 1 217 ? -33.281 64.999  -26.639 1    130.71 ? 206 SER D N   1 -0.305 0.596  -0.067 
ATOM   10969 C  CA  . SER D 1 217 ? -34.469 65.821  -26.438 1    133.71 ? 206 SER D CA  1 -0.316 0.603  -0.066 
ATOM   10970 C  C   . SER D 1 217 ? -34.156 67.197  -25.867 1    135.57 ? 206 SER D C   1 -0.313 0.616  -0.065 
ATOM   10971 O  O   . SER D 1 217 ? -35.086 67.971  -25.603 1    134.27 ? 206 SER D O   1 -0.322 0.623  -0.064 
ATOM   10972 C  CB  . SER D 1 217 ? -35.461 65.103  -25.511 1    138.19 ? 206 SER D CB  1 -0.325 0.597  -0.064 
ATOM   10973 O  OG  . SER D 1 217 ? -35.736 63.8    -25.996 1    139.98 ? 206 SER D OG  1 -0.327 0.585  -0.065 
ATOM   10974 N  N   . SER D 1 218 ? -32.884 67.528  -25.677 1    138.15 ? 207 SER D N   1 -0.301 0.619  -0.064 
ATOM   10975 C  CA  . SER D 1 218 ? -32.478 68.736  -24.972 1    148.16 ? 207 SER D CA  1 -0.298 0.63   -0.062 
ATOM   10976 C  C   . SER D 1 218 ? -31.942 69.763  -25.963 1    146.16 ? 207 SER D C   1 -0.293 0.639  -0.065 
ATOM   10977 O  O   . SER D 1 218 ? -31.301 69.404  -26.959 1    144.01 ? 207 SER D O   1 -0.287 0.636  -0.067 
ATOM   10978 C  CB  . SER D 1 218 ? -31.424 68.409  -23.897 1    145.4  ? 207 SER D CB  1 -0.288 0.627  -0.06  
ATOM   10979 O  OG  . SER D 1 218 ? -30.877 69.574  -23.293 1    144.22 ? 207 SER D OG  1 -0.283 0.638  -0.058 
ATOM   10980 N  N   . ALA D 1 219 ? -32.226 71.041  -25.681 1    145.11 ? 208 ALA D N   1 -0.295 0.651  -0.064 
ATOM   10981 C  CA  . ALA D 1 219 ? -31.787 72.163  -26.505 1    147.84 ? 208 ALA D CA  1 -0.291 0.661  -0.066 
ATOM   10982 C  C   . ALA D 1 219 ? -30.275 72.134  -26.695 1    149.59 ? 208 ALA D C   1 -0.277 0.661  -0.067 
ATOM   10983 O  O   . ALA D 1 219 ? -29.77  71.526  -27.647 1    149.88 ? 208 ALA D O   1 -0.273 0.655  -0.069 
ATOM   10984 C  CB  . ALA D 1 219 ? -32.231 73.484  -25.875 1    141.1  ? 208 ALA D CB  1 -0.295 0.673  -0.065 
ATOM   10985 N  N   . GLN D 1 220 ? -29.545 72.803  -25.816 1    146.11 ? 209 GLN D N   1 -0.271 0.667  -0.064 
ATOM   10986 C  CA  . GLN D 1 220 ? -28.122 72.527  -25.68  1    151.47 ? 209 GLN D CA  1 -0.258 0.665  -0.064 
ATOM   10987 C  C   . GLN D 1 220 ? -27.968 71.268  -24.832 1    148.4  ? 209 GLN D C   1 -0.256 0.653  -0.062 
ATOM   10988 O  O   . GLN D 1 220 ? -28.472 71.234  -23.702 1    146.46 ? 209 GLN D O   1 -0.261 0.653  -0.059 
ATOM   10989 C  CB  . GLN D 1 220 ? -27.388 73.714  -25.042 1    155.97 ? 209 GLN D CB  1 -0.251 0.676  -0.063 
ATOM   10990 C  CG  . GLN D 1 220 ? -25.848 73.58   -24.911 1    150.3  ? 209 GLN D CG  1 -0.237 0.674  -0.062 
ATOM   10991 C  CD  . GLN D 1 220 ? -25.087 73.783  -26.232 1    150.62 ? 209 GLN D CD  1 -0.23  0.676  -0.065 
ATOM   10992 O  OE1 . GLN D 1 220 ? -25.628 73.561  -27.323 1    146.57 ? 209 GLN D OE1 1 -0.235 0.674  -0.068 
ATOM   10993 N  NE2 . GLN D 1 220 ? -23.824 74.206  -26.129 1    134.56 ? 209 GLN D NE2 1 -0.218 0.68   -0.065 
ATOM   10994 N  N   . PRO D 1 221 ? -27.335 70.214  -25.343 1    145.09 ? 210 PRO D N   1 -0.251 0.643  -0.063 
ATOM   10995 C  CA  . PRO D 1 221 ? -27.218 68.96   -24.585 1    142.39 ? 210 PRO D CA  1 -0.249 0.632  -0.061 
ATOM   10996 C  C   . PRO D 1 221 ? -26.691 69.202  -23.181 1    140.7  ? 210 PRO D C   1 -0.245 0.634  -0.058 
ATOM   10997 O  O   . PRO D 1 221 ? -25.697 69.923  -22.987 1    134.72 ? 210 PRO D O   1 -0.235 0.641  -0.057 
ATOM   10998 C  CB  . PRO D 1 221 ? -26.232 68.138  -25.426 1    136.14 ? 210 PRO D CB  1 -0.24  0.624  -0.063 
ATOM   10999 C  CG  . PRO D 1 221 ? -26.486 68.614  -26.817 1    145.35 ? 210 PRO D CG  1 -0.243 0.629  -0.067 
ATOM   11000 C  CD  . PRO D 1 221 ? -26.795 70.088  -26.708 1    145.41 ? 210 PRO D CD  1 -0.246 0.642  -0.067 
ATOM   11001 N  N   . PRO D 1 222 ? -27.337 68.616  -22.172 1    134.71 ? 211 PRO D N   1 -0.251 0.629  -0.055 
ATOM   11002 C  CA  . PRO D 1 222 ? -27.042 68.997  -20.793 1    135.47 ? 211 PRO D CA  1 -0.248 0.632  -0.052 
ATOM   11003 C  C   . PRO D 1 222 ? -25.662 68.523  -20.375 1    134.12 ? 211 PRO D C   1 -0.235 0.628  -0.051 
ATOM   11004 O  O   . PRO D 1 222 ? -25.127 67.543  -20.905 1    132.37 ? 211 PRO D O   1 -0.23  0.619  -0.052 
ATOM   11005 C  CB  . PRO D 1 222 ? -28.143 68.297  -19.993 1    132.63 ? 211 PRO D CB  1 -0.258 0.626  -0.05  
ATOM   11006 C  CG  . PRO D 1 222 ? -28.461 67.089  -20.809 1    131.31 ? 211 PRO D CG  1 -0.261 0.615  -0.052 
ATOM   11007 C  CD  . PRO D 1 222 ? -28.28  67.485  -22.242 1    133.36 ? 211 PRO D CD  1 -0.259 0.618  -0.056 
ATOM   11008 N  N   . LYS D 1 223 ? -25.072 69.265  -19.437 1    126.45 ? 212 LYS D N   1 -0.23  0.635  -0.049 
ATOM   11009 C  CA  . LYS D 1 223 ? -23.769 68.905  -18.901 1    125.32 ? 212 LYS D CA  1 -0.218 0.631  -0.047 
ATOM   11010 C  C   . LYS D 1 223 ? -23.916 67.644  -18.063 1    133.86 ? 212 LYS D C   1 -0.219 0.62   -0.045 
ATOM   11011 O  O   . LYS D 1 223 ? -24.706 67.625  -17.109 1    136.01 ? 212 LYS D O   1 -0.226 0.62   -0.043 
ATOM   11012 C  CB  . LYS D 1 223 ? -23.2   70.043  -18.06  1    128.79 ? 212 LYS D CB  1 -0.213 0.642  -0.045 
ATOM   11013 C  CG  . LYS D 1 223 ? -21.855 69.688  -17.453 1    129.62 ? 212 LYS D CG  1 -0.2   0.639  -0.044 
ATOM   11014 C  CD  . LYS D 1 223 ? -20.824 69.669  -18.556 1    136.98 ? 212 LYS D CD  1 -0.191 0.638  -0.046 
ATOM   11015 C  CE  . LYS D 1 223 ? -20.855 71.001  -19.336 1    135.54 ? 212 LYS D CE  1 -0.191 0.651  -0.048 
ATOM   11016 N  NZ  . LYS D 1 223 ? -20.107 70.974  -20.634 1    135.18 ? 212 LYS D NZ  1 -0.184 0.65   -0.052 
ATOM   11017 N  N   . PHE D 1 224 ? -23.18  66.587  -18.42  1    131.41 ? 213 PHE D N   1 -0.212 0.61   -0.046 
ATOM   11018 C  CA  . PHE D 1 224 ? -23.359 65.268  -17.815 1    129.17 ? 213 PHE D CA  1 -0.214 0.598  -0.044 
ATOM   11019 C  C   . PHE D 1 224 ? -22.393 65.105  -16.647 1    126.26 ? 213 PHE D C   1 -0.205 0.597  -0.042 
ATOM   11020 O  O   . PHE D 1 224 ? -21.192 65.343  -16.794 1    128.64 ? 213 PHE D O   1 -0.194 0.599  -0.042 
ATOM   11021 C  CB  . PHE D 1 224 ? -23.164 64.14   -18.841 1    131.94 ? 213 PHE D CB  1 -0.212 0.588  -0.047 
ATOM   11022 C  CG  . PHE D 1 224 ? -24.392 63.884  -19.708 1    136.16 ? 213 PHE D CG  1 -0.224 0.585  -0.049 
ATOM   11023 C  CD1 . PHE D 1 224 ? -24.57  64.553  -20.91  1    129.01 ? 213 PHE D CD1 1 -0.225 0.592  -0.052 
ATOM   11024 C  CD2 . PHE D 1 224 ? -25.405 63.017  -19.247 1    135.98 ? 213 PHE D CD2 1 -0.233 0.577  -0.048 
ATOM   11025 C  CE1 . PHE D 1 224 ? -25.7   64.361  -21.669 1    126.54 ? 213 PHE D CE1 1 -0.236 0.59   -0.054 
ATOM   11026 C  CE2 . PHE D 1 224 ? -26.536 62.804  -20.038 1    134.06 ? 213 PHE D CE2 1 -0.243 0.576  -0.05  
ATOM   11027 C  CZ  . PHE D 1 224 ? -26.682 63.481  -21.238 1    125.04 ? 213 PHE D CZ  1 -0.245 0.582  -0.053 
ATOM   11028 N  N   . VAL D 1 225 ? -22.919 64.712  -15.488 1    124.3  ? 214 VAL D N   1 -0.21  0.593  -0.039 
ATOM   11029 C  CA  . VAL D 1 225 ? -22.11  64.374  -14.323 1    119.97 ? 214 VAL D CA  1 -0.203 0.59   -0.036 
ATOM   11030 C  C   . VAL D 1 225 ? -22.509 62.977  -13.867 1    115.13 ? 214 VAL D C   1 -0.206 0.577  -0.035 
ATOM   11031 O  O   . VAL D 1 225 ? -23.701 62.69   -13.693 1    108.43 ? 214 VAL D O   1 -0.217 0.574  -0.034 
ATOM   11032 C  CB  . VAL D 1 225 ? -22.273 65.402  -13.181 1    123.64 ? 214 VAL D CB  1 -0.204 0.599  -0.033 
ATOM   11033 C  CG1 . VAL D 1 225 ? -21.919 64.784  -11.828 1    116.75 ? 214 VAL D CG1 1 -0.201 0.594  -0.03  
ATOM   11034 C  CG2 . VAL D 1 225 ? -21.384 66.621  -13.435 1    125.2  ? 214 VAL D CG2 1 -0.196 0.611  -0.034 
ATOM   11035 N  N   . ILE D 1 226 ? -21.513 62.113  -13.685 1    116.47 ? 215 ILE D N   1 -0.197 0.569  -0.034 
ATOM   11036 C  CA  . ILE D 1 226 ? -21.721 60.707  -13.361 1    116.1  ? 215 ILE D CA  1 -0.199 0.556  -0.033 
ATOM   11037 C  C   . ILE D 1 226 ? -20.933 60.366  -12.1   1    116.13 ? 215 ILE D C   1 -0.192 0.553  -0.03  
ATOM   11038 O  O   . ILE D 1 226 ? -19.697 60.45   -12.092 1    114.75 ? 215 ILE D O   1 -0.181 0.554  -0.03  
ATOM   11039 C  CB  . ILE D 1 226 ? -21.297 59.788  -14.518 1    116.02 ? 215 ILE D CB  1 -0.195 0.548  -0.036 
ATOM   11040 C  CG1 . ILE D 1 226 ? -21.958 60.216  -15.809 1    115.99 ? 215 ILE D CG1 1 -0.201 0.552  -0.039 
ATOM   11041 C  CG2 . ILE D 1 226 ? -21.695 58.353  -14.235 1    115.44 ? 215 ILE D CG2 1 -0.199 0.535  -0.036 
ATOM   11042 C  CD1 . ILE D 1 226 ? -21.645 59.272  -16.941 1    127    ? 215 ILE D CD1 1 -0.198 0.543  -0.042 
ATOM   11043 N  N   . ILE D 1 227 ? -21.641 59.979  -11.045 1    113.45 ? 216 ILE D N   1 -0.198 0.55   -0.028 
ATOM   11044 C  CA  . ILE D 1 227 ? -21.034 59.404  -9.848  1    113.24 ? 216 ILE D CA  1 -0.193 0.544  -0.025 
ATOM   11045 C  C   . ILE D 1 227 ? -21.533 57.973  -9.746  1    110.36 ? 216 ILE D C   1 -0.197 0.531  -0.024 
ATOM   11046 O  O   . ILE D 1 227 ? -22.745 57.728  -9.784  1    108.75 ? 216 ILE D O   1 -0.208 0.529  -0.024 
ATOM   11047 C  CB  . ILE D 1 227 ? -21.366 60.21   -8.583  1    110.19 ? 216 ILE D CB  1 -0.196 0.552  -0.021 
ATOM   11048 C  CG1 . ILE D 1 227 ? -20.399 61.38   -8.417  1    109.6  ? 216 ILE D CG1 1 -0.187 0.562  -0.021 
ATOM   11049 C  CG2 . ILE D 1 227 ? -21.34  59.314  -7.353  1    110.07 ? 216 ILE D CG2 1 -0.196 0.544  -0.018 
ATOM   11050 C  CD1 . ILE D 1 227 ? -20.865 62.393  -7.408  1    109.69 ? 216 ILE D CD1 1 -0.191 0.572  -0.018 
ATOM   11051 N  N   . GLY D 1 228 ? -20.601 57.032  -9.634  1    108.58 ? 217 GLY D N   1 -0.189 0.523  -0.024 
ATOM   11052 C  CA  . GLY D 1 228 ? -20.948 55.625  -9.601  1    110.08 ? 217 GLY D CA  1 -0.192 0.51   -0.024 
ATOM   11053 C  C   . GLY D 1 228 ? -20.136 54.902  -8.552  1    111.14 ? 217 GLY D C   1 -0.185 0.503  -0.021 
ATOM   11054 O  O   . GLY D 1 228 ? -18.916 54.742  -8.7    1    110.3  ? 217 GLY D O   1 -0.173 0.502  -0.022 
ATOM   11055 N  N   . THR D 1 229 ? -20.815 54.449  -7.497  1    114.63 ? 218 THR D N   1 -0.191 0.499  -0.019 
ATOM   11056 C  CA  . THR D 1 229 ? -20.176 54.108  -6.229  1    109.85 ? 218 THR D CA  1 -0.185 0.496  -0.016 
ATOM   11057 C  C   . THR D 1 229 ? -20.051 52.61   -5.969  1    107.26 ? 218 THR D C   1 -0.184 0.482  -0.015 
ATOM   11058 O  O   . THR D 1 229 ? -19.448 52.236  -4.958  1    108.26 ? 218 THR D O   1 -0.178 0.479  -0.012 
ATOM   11059 C  CB  . THR D 1 229 ? -20.95  54.754  -5.078  1    104.46 ? 218 THR D CB  1 -0.192 0.502  -0.013 
ATOM   11060 O  OG1 . THR D 1 229 ? -22.325 54.35   -5.148  1    106.68 ? 218 THR D OG1 1 -0.205 0.498  -0.013 
ATOM   11061 C  CG2 . THR D 1 229 ? -20.868 56.264  -5.191  1    101.1  ? 218 THR D CG2 1 -0.191 0.516  -0.013 
ATOM   11062 N  N   . ASP D 1 230 ? -20.62  51.756  -6.829  1    103.9  ? 219 ASP D N   1 -0.189 0.474  -0.017 
ATOM   11063 C  CA  . ASP D 1 230 ? -20.343 50.322  -6.823  1    102.38 ? 219 ASP D CA  1 -0.186 0.461  -0.017 
ATOM   11064 C  C   . ASP D 1 230 ? -18.853 50.065  -6.587  1    105.16 ? 219 ASP D C   1 -0.173 0.459  -0.016 
ATOM   11065 O  O   . ASP D 1 230 ? -17.996 50.778  -7.116  1    110.61 ? 219 ASP D O   1 -0.165 0.465  -0.018 
ATOM   11066 C  CB  . ASP D 1 230 ? -20.805 49.734  -8.166  1    105.97 ? 219 ASP D CB  1 -0.191 0.456  -0.02  
ATOM   11067 C  CG  . ASP D 1 230 ? -20.771 48.208  -8.216  1    105.33 ? 219 ASP D CG  1 -0.19  0.442  -0.021 
ATOM   11068 O  OD1 . ASP D 1 230 ? -19.67  47.628  -8.394  1    98.58  ? 219 ASP D OD1 1 -0.18  0.436  -0.021 
ATOM   11069 O  OD2 . ASP D 1 230 ? -21.864 47.597  -8.112  1    104.4  ? 219 ASP D OD2 1 -0.2   0.436  -0.02  
ATOM   11070 N  N   . VAL D 1 231 ? -18.544 49.06   -5.762  1    98.32  ? 220 VAL D N   1 -0.17  0.45   -0.014 
ATOM   11071 C  CA  . VAL D 1 231 ? -17.152 48.815  -5.386  1    102.07 ? 220 VAL D CA  1 -0.157 0.447  -0.013 
ATOM   11072 C  C   . VAL D 1 231 ? -16.314 48.449  -6.604  1    99.57  ? 220 VAL D C   1 -0.15  0.444  -0.016 
ATOM   11073 O  O   . VAL D 1 231 ? -15.117 48.759  -6.666  1    97.29  ? 220 VAL D O   1 -0.139 0.447  -0.017 
ATOM   11074 C  CB  . VAL D 1 231 ? -17.09  47.729  -4.281  1    106.6  ? 220 VAL D CB  1 -0.157 0.437  -0.011 
ATOM   11075 C  CG1 . VAL D 1 231 ? -17.805 46.45   -4.716  1    103.8  ? 220 VAL D CG1 1 -0.163 0.426  -0.012 
ATOM   11076 C  CG2 . VAL D 1 231 ? -15.644 47.453  -3.833  1    106.06 ? 220 VAL D CG2 1 -0.143 0.435  -0.01  
ATOM   11077 N  N   . ASN D 1 232 ? -16.93  47.804  -7.593  1    108.82 ? 221 ASN D N   1 -0.155 0.438  -0.019 
ATOM   11078 C  CA  . ASN D 1 232 ? -16.255 47.404  -8.825  1    113.02 ? 221 ASN D CA  1 -0.149 0.434  -0.022 
ATOM   11079 C  C   . ASN D 1 232 ? -16.213 48.552  -9.836  1    109.31 ? 221 ASN D C   1 -0.149 0.445  -0.025 
ATOM   11080 O  O   . ASN D 1 232 ? -17.157 49.347  -9.931  1    109.14 ? 221 ASN D O   1 -0.157 0.452  -0.025 
ATOM   11081 C  CB  . ASN D 1 232 ? -16.979 46.2    -9.424  1    109.94 ? 221 ASN D CB  1 -0.156 0.423  -0.024 
ATOM   11082 C  CG  . ASN D 1 232 ? -17.4   45.202  -8.364  1    105.8  ? 221 ASN D CG  1 -0.159 0.414  -0.021 
ATOM   11083 O  OD1 . ASN D 1 232 ? -18.585 45.067  -8.061  1    102.79 ? 221 ASN D OD1 1 -0.17  0.413  -0.02  
ATOM   11084 N  ND2 . ASN D 1 232 ? -16.425 44.504  -7.786  1    105.68 ? 221 ASN D ND2 1 -0.151 0.408  -0.019 
ATOM   11085 N  N   . ARG D 1 233 ? -15.103 48.638  -10.583 1    107.3  ? 222 ARG D N   1 -0.138 0.446  -0.026 
ATOM   11086 C  CA  . ARG D 1 233 ? -14.929 49.684  -11.592 1    109.55 ? 222 ARG D CA  1 -0.137 0.455  -0.029 
ATOM   11087 C  C   . ARG D 1 233 ? -16.113 49.717  -12.551 1    104.13 ? 222 ARG D C   1 -0.148 0.456  -0.031 
ATOM   11088 O  O   . ARG D 1 233 ? -16.687 48.678  -12.884 1    105.37 ? 222 ARG D O   1 -0.153 0.446  -0.032 
ATOM   11089 C  CB  . ARG D 1 233 ? -13.615 49.458  -12.359 1    105.69 ? 222 ARG D CB  1 -0.125 0.453  -0.031 
ATOM   11090 C  CG  . ARG D 1 233 ? -13.538 50.133  -13.724 1    115.19 ? 222 ARG D CG  1 -0.124 0.459  -0.034 
ATOM   11091 C  CD  . ARG D 1 233 ? -12.083 50.387  -14.209 1    122.43 ? 222 ARG D CD  1 -0.111 0.462  -0.035 
ATOM   11092 N  NE  . ARG D 1 233 ? -11.957 50.318  -15.666 1    117.51 ? 222 ARG D NE  1 -0.11  0.461  -0.039 
ATOM   11093 C  CZ  . ARG D 1 233 ? -12.106 51.348  -16.491 1    123.09 ? 222 ARG D CZ  1 -0.111 0.471  -0.041 
ATOM   11094 N  NH1 . ARG D 1 233 ? -12.295 52.574  -16.037 1    123.77 ? 222 ARG D NH1 1 -0.113 0.482  -0.04  
ATOM   11095 N  NH2 . ARG D 1 233 ? -12.072 51.141  -17.806 1    123.28 ? 222 ARG D NH2 1 -0.111 0.469  -0.044 
ATOM   11096 N  N   . ASP D 1 234 ? -16.508 50.923  -12.966 1    104.89 ? 223 ASP D N   1 -0.151 0.467  -0.032 
ATOM   11097 C  CA  . ASP D 1 234 ? -17.49  51.075  -14.051 1    113.14 ? 223 ASP D CA  1 -0.16  0.468  -0.035 
ATOM   11098 C  C   . ASP D 1 234 ? -16.787 50.947  -15.407 1    110.2  ? 223 ASP D C   1 -0.154 0.467  -0.038 
ATOM   11099 O  O   . ASP D 1 234 ? -16.577 51.921  -16.133 1    111.84 ? 223 ASP D O   1 -0.152 0.476  -0.04  
ATOM   11100 C  CB  . ASP D 1 234 ? -18.213 52.413  -13.97  1    113.2  ? 223 ASP D CB  1 -0.167 0.48   -0.035 
ATOM   11101 C  CG  . ASP D 1 234 ? -18.569 52.818  -12.558 1    115.32 ? 223 ASP D CG  1 -0.17  0.484  -0.031 
ATOM   11102 O  OD1 . ASP D 1 234 ? -18.86  51.946  -11.697 1    112.56 ? 223 ASP D OD1 1 -0.173 0.476  -0.029 
ATOM   11103 O  OD2 . ASP D 1 234 ? -18.567 54.047  -12.33  1    116.63 ? 223 ASP D OD2 1 -0.17  0.495  -0.031 
ATOM   11104 N  N   . ASN D 1 235 ? -16.417 49.713  -15.756 1    110.76 ? 224 ASN D N   1 -0.15  0.456  -0.039 
ATOM   11105 C  CA  . ASN D 1 235 ? -15.634 49.522  -16.975 1    113.35 ? 224 ASN D CA  1 -0.143 0.454  -0.042 
ATOM   11106 C  C   . ASN D 1 235 ? -16.526 49.538  -18.214 1    111.62 ? 224 ASN D C   1 -0.151 0.454  -0.045 
ATOM   11107 O  O   . ASN D 1 235 ? -16.228 50.226  -19.195 1    106.83 ? 224 ASN D O   1 -0.149 0.46   -0.048 
ATOM   11108 C  CB  . ASN D 1 235 ? -14.814 48.227  -16.883 1    106.89 ? 224 ASN D CB  1 -0.136 0.442  -0.042 
ATOM   11109 C  CG  . ASN D 1 235 ? -15.677 46.996  -16.648 1    112.38 ? 224 ASN D CG  1 -0.144 0.431  -0.042 
ATOM   11110 O  OD1 . ASN D 1 235 ? -16.837 47.094  -16.233 1    112.86 ? 224 ASN D OD1 1 -0.154 0.432  -0.041 
ATOM   11111 N  ND2 . ASN D 1 235 ? -15.109 45.822  -16.91  1    114.43 ? 224 ASN D ND2 1 -0.138 0.42   -0.042 
ATOM   11112 N  N   . GLY D 1 236 ? -17.642 48.81   -18.169 1    110.61 ? 225 GLY D N   1 -0.162 0.447  -0.045 
ATOM   11113 C  CA  . GLY D 1 236 ? -18.571 48.818  -19.289 1    111.54 ? 225 GLY D CA  1 -0.17  0.447  -0.048 
ATOM   11114 C  C   . GLY D 1 236 ? -18.994 50.214  -19.701 1    112.29 ? 225 GLY D C   1 -0.174 0.46   -0.049 
ATOM   11115 O  O   . GLY D 1 236 ? -18.98  50.553  -20.881 1    116.09 ? 225 GLY D O   1 -0.174 0.463  -0.052 
ATOM   11116 N  N   . LEU D 1 237 ? -19.385 51.048  -18.736 1    114.94 ? 226 LEU D N   1 -0.178 0.468  -0.047 
ATOM   11117 C  CA  . LEU D 1 237 ? -19.843 52.388  -19.096 1    115.85 ? 226 LEU D CA  1 -0.182 0.48   -0.048 
ATOM   11118 C  C   . LEU D 1 237 ? -18.683 53.268  -19.53  1    116.23 ? 226 LEU D C   1 -0.171 0.488  -0.049 
ATOM   11119 O  O   . LEU D 1 237 ? -18.82  54.058  -20.473 1    116.34 ? 226 LEU D O   1 -0.172 0.495  -0.051 
ATOM   11120 C  CB  . LEU D 1 237 ? -20.591 53.046  -17.933 1    114.53 ? 226 LEU D CB  1 -0.189 0.486  -0.045 
ATOM   11121 C  CG  . LEU D 1 237 ? -21.16  54.441  -18.229 1    114.67 ? 226 LEU D CG  1 -0.194 0.499  -0.046 
ATOM   11122 C  CD1 . LEU D 1 237 ? -22.449 54.357  -19.042 1    111.17 ? 226 LEU D CD1 1 -0.206 0.498  -0.048 
ATOM   11123 C  CD2 . LEU D 1 237 ? -21.379 55.229  -16.942 1    118.6  ? 226 LEU D CD2 1 -0.196 0.506  -0.042 
ATOM   11124 N  N   . CYS D 1 238 ? -17.533 53.144  -18.856 1    111.2  ? 227 CYS D N   1 -0.161 0.487  -0.047 
ATOM   11125 C  CA  . CYS D 1 238 ? -16.363 53.927  -19.239 1    113.51 ? 227 CYS D CA  1 -0.15  0.494  -0.048 
ATOM   11126 C  C   . CYS D 1 238 ? -16.025 53.723  -20.713 1    118.44 ? 227 CYS D C   1 -0.147 0.492  -0.052 
ATOM   11127 O  O   . CYS D 1 238 ? -15.63  54.672  -21.402 1    118.8  ? 227 CYS D O   1 -0.143 0.501  -0.053 
ATOM   11128 C  CB  . CYS D 1 238 ? -15.176 53.549  -18.355 1    112.98 ? 227 CYS D CB  1 -0.139 0.491  -0.046 
ATOM   11129 S  SG  . CYS D 1 238 ? -13.687 54.551  -18.587 1    119.77 ? 227 CYS D SG  1 -0.125 0.5    -0.046 
ATOM   11130 N  N   . ASP D 1 239 ? -16.21  52.497  -21.218 1    117.46 ? 228 ASP D N   1 -0.149 0.481  -0.053 
ATOM   11131 C  CA  . ASP D 1 239 ? -15.844 52.168  -22.595 1    112.41 ? 228 ASP D CA  1 -0.145 0.478  -0.056 
ATOM   11132 C  C   . ASP D 1 239 ? -16.792 52.828  -23.592 1    112.08 ? 228 ASP D C   1 -0.154 0.484  -0.059 
ATOM   11133 O  O   . ASP D 1 239 ? -16.358 53.593  -24.458 1    114.53 ? 228 ASP D O   1 -0.15  0.491  -0.061 
ATOM   11134 C  CB  . ASP D 1 239 ? -15.834 50.651  -22.769 1    112.8  ? 228 ASP D CB  1 -0.145 0.464  -0.057 
ATOM   11135 C  CG  . ASP D 1 239 ? -14.972 50.196  -23.933 1    123.09 ? 228 ASP D CG  1 -0.137 0.46   -0.06  
ATOM   11136 O  OD1 . ASP D 1 239 ? -13.82  50.671  -24.044 1    123.86 ? 228 ASP D OD1 1 -0.127 0.464  -0.06  
ATOM   11137 O  OD2 . ASP D 1 239 ? -15.447 49.351  -24.729 1    125.44 ? 228 ASP D OD2 1 -0.142 0.452  -0.062 
ATOM   11138 N  N   . ILE D 1 240 ? -18.095 52.548  -23.478 1    105.86 ? 229 ILE D N   1 -0.166 0.482  -0.059 
ATOM   11139 C  CA  . ILE D 1 240 ? -19.106 53.172  -24.331 1    104.22 ? 229 ILE D CA  1 -0.175 0.487  -0.061 
ATOM   11140 C  C   . ILE D 1 240 ? -18.975 54.687  -24.371 1    114.92 ? 229 ILE D C   1 -0.174 0.501  -0.061 
ATOM   11141 O  O   . ILE D 1 240 ? -19.351 55.322  -25.366 1    115.95 ? 229 ILE D O   1 -0.177 0.507  -0.063 
ATOM   11142 C  CB  . ILE D 1 240 ? -20.515 52.77   -23.862 1    105.32 ? 229 ILE D CB  1 -0.188 0.484  -0.06  
ATOM   11143 C  CG1 . ILE D 1 240 ? -20.577 51.289  -23.532 1    106.26 ? 229 ILE D CG1 1 -0.189 0.47   -0.059 
ATOM   11144 C  CG2 . ILE D 1 240 ? -21.556 53.103  -24.919 1    113.35 ? 229 ILE D CG2 1 -0.198 0.487  -0.062 
ATOM   11145 C  CD1 . ILE D 1 240 ? -21.904 50.932  -22.931 1    110.26 ? 229 ILE D CD1 1 -0.201 0.467  -0.057 
ATOM   11146 N  N   . LEU D 1 241 ? -18.477 55.303  -23.295 1    117.71 ? 230 LEU D N   1 -0.169 0.507  -0.058 
ATOM   11147 C  CA  . LEU D 1 241 ? -18.319 56.752  -23.332 1    120.37 ? 230 LEU D CA  1 -0.168 0.52   -0.058 
ATOM   11148 C  C   . LEU D 1 241 ? -17.009 57.136  -24.008 1    124.07 ? 230 LEU D C   1 -0.156 0.524  -0.06  
ATOM   11149 O  O   . LEU D 1 241 ? -16.953 58.126  -24.751 1    126.16 ? 230 LEU D O   1 -0.155 0.533  -0.062 
ATOM   11150 C  CB  . LEU D 1 241 ? -18.398 57.341  -21.923 1    118.8  ? 230 LEU D CB  1 -0.169 0.525  -0.055 
ATOM   11151 C  CG  . LEU D 1 241 ? -19.589 56.985  -21.023 1    123.04 ? 230 LEU D CG  1 -0.18  0.522  -0.052 
ATOM   11152 C  CD1 . LEU D 1 241 ? -19.752 58.019  -19.913 1    125.96 ? 230 LEU D CD1 1 -0.181 0.532  -0.05  
ATOM   11153 C  CD2 . LEU D 1 241 ? -20.887 56.824  -21.804 1    118.69 ? 230 LEU D CD2 1 -0.191 0.521  -0.054 
ATOM   11154 N  N   . ARG D 1 242 ? -15.962 56.341  -23.775 1    120.57 ? 231 ARG D N   1 -0.146 0.516  -0.059 
ATOM   11155 C  CA  . ARG D 1 242 ? -14.68  56.541  -24.444 1    124    ? 231 ARG D CA  1 -0.135 0.518  -0.061 
ATOM   11156 C  C   . ARG D 1 242 ? -14.859 56.728  -25.951 1    128.92 ? 231 ARG D C   1 -0.136 0.52   -0.065 
ATOM   11157 O  O   . ARG D 1 242 ? -14.325 57.676  -26.537 1    136.85 ? 231 ARG D O   1 -0.131 0.529  -0.066 
ATOM   11158 C  CB  . ARG D 1 242 ? -13.762 55.352  -24.149 1    124.96 ? 231 ARG D CB  1 -0.126 0.507  -0.06  
ATOM   11159 C  CG  . ARG D 1 242 ? -12.305 55.698  -24.007 1    125.69 ? 231 ARG D CG  1 -0.113 0.51   -0.06  
ATOM   11160 C  CD  . ARG D 1 242 ? -11.423 54.521  -24.394 1    130.15 ? 231 ARG D CD  1 -0.105 0.5    -0.061 
ATOM   11161 N  NE  . ARG D 1 242 ? -10.031 54.943  -24.461 1    137.36 ? 231 ARG D NE  1 -0.092 0.504  -0.061 
ATOM   11162 C  CZ  . ARG D 1 242 ? -9.536  55.729  -25.411 1    140.15 ? 231 ARG D CZ  1 -0.087 0.511  -0.063 
ATOM   11163 N  NH1 . ARG D 1 242 ? -10.285 56.16   -26.412 1    142.26 ? 231 ARG D NH1 1 -0.094 0.515  -0.066 
ATOM   11164 N  NH2 . ARG D 1 242 ? -8.261  56.097  -25.352 1    139.51 ? 231 ARG D NH2 1 -0.076 0.514  -0.063 
ATOM   11165 N  N   . HIS D 1 243 ? -15.63  55.846  -26.594 1    125.48 ? 232 HIS D N   1 -0.143 0.512  -0.066 
ATOM   11166 C  CA  . HIS D 1 243 ? -15.789 55.889  -28.044 1    128.92 ? 232 HIS D CA  1 -0.145 0.512  -0.07  
ATOM   11167 C  C   . HIS D 1 243 ? -16.817 56.925  -28.483 1    125.39 ? 232 HIS D C   1 -0.154 0.522  -0.071 
ATOM   11168 O  O   . HIS D 1 243 ? -16.474 58.019  -28.95  1    116.82 ? 232 HIS D O   1 -0.151 0.532  -0.072 
ATOM   11169 C  CB  . HIS D 1 243 ? -16.216 54.517  -28.589 1    125.62 ? 232 HIS D CB  1 -0.149 0.5    -0.071 
ATOM   11170 C  CG  . HIS D 1 243 ? -15.213 53.432  -28.348 1    134.46 ? 232 HIS D CG  1 -0.139 0.49   -0.071 
ATOM   11171 N  ND1 . HIS D 1 243 ? -15.567 52.105  -28.212 1    135.54 ? 232 HIS D ND1 1 -0.143 0.477  -0.07  
ATOM   11172 C  CD2 . HIS D 1 243 ? -13.865 53.478  -28.218 1    133.83 ? 232 HIS D CD2 1 -0.127 0.49   -0.07  
ATOM   11173 C  CE1 . HIS D 1 243 ? -14.479 51.381  -28.009 1    137.35 ? 232 HIS D CE1 1 -0.133 0.471  -0.07  
ATOM   11174 N  NE2 . HIS D 1 243 ? -13.434 52.19   -28.008 1    137.46 ? 232 HIS D NE2 1 -0.123 0.478  -0.07  
ATOM   11175 N  N   . SER D 1 244 ? -18.086 56.578  -28.285 1    127.19 ? 233 SER D N   1 -0.166 0.518  -0.071 
ATOM   11176 C  CA  . SER D 1 244 ? -19.221 57.164  -28.979 1    123.91 ? 233 SER D CA  1 -0.176 0.524  -0.072 
ATOM   11177 C  C   . SER D 1 244 ? -19.931 58.252  -28.169 1    124.87 ? 233 SER D C   1 -0.183 0.534  -0.07  
ATOM   11178 O  O   . SER D 1 244 ? -21.074 58.611  -28.494 1    117.68 ? 233 SER D O   1 -0.193 0.537  -0.071 
ATOM   11179 C  CB  . SER D 1 244 ? -20.202 56.05   -29.339 1    121.54 ? 233 SER D CB  1 -0.185 0.514  -0.073 
ATOM   11180 O  OG  . SER D 1 244 ? -19.59  54.785  -29.113 1    115.44 ? 233 SER D OG  1 -0.18  0.502  -0.073 
ATOM   11181 N  N   . PHE D 1 245 ? -19.299 58.764  -27.111 1    128.88 ? 234 PHE D N   1 -0.177 0.539  -0.068 
ATOM   11182 C  CA  . PHE D 1 245 ? -19.912 59.831  -26.323 1    126.04 ? 234 PHE D CA  1 -0.182 0.548  -0.066 
ATOM   11183 C  C   . PHE D 1 245 ? -18.967 60.976  -25.973 1    126.17 ? 234 PHE D C   1 -0.174 0.559  -0.065 
ATOM   11184 O  O   . PHE D 1 245 ? -19.456 62.024  -25.535 1    122.74 ? 234 PHE D O   1 -0.178 0.568  -0.064 
ATOM   11185 C  CB  . PHE D 1 245 ? -20.515 59.263  -25.025 1    123.64 ? 234 PHE D CB  1 -0.188 0.543  -0.062 
ATOM   11186 C  CG  . PHE D 1 245 ? -21.819 58.524  -25.219 1    122.89 ? 234 PHE D CG  1 -0.2   0.536  -0.063 
ATOM   11187 C  CD1 . PHE D 1 245 ? -21.832 57.207  -25.649 1    121.43 ? 234 PHE D CD1 1 -0.2   0.524  -0.064 
ATOM   11188 C  CD2 . PHE D 1 245 ? -23.034 59.141  -24.944 1    123.34 ? 234 PHE D CD2 1 -0.211 0.542  -0.062 
ATOM   11189 C  CE1 . PHE D 1 245 ? -23.033 56.522  -25.82  1    121.47 ? 234 PHE D CE1 1 -0.211 0.518  -0.064 
ATOM   11190 C  CE2 . PHE D 1 245 ? -24.236 58.46   -25.112 1    118.36 ? 234 PHE D CE2 1 -0.222 0.536  -0.063 
ATOM   11191 C  CZ  . PHE D 1 245 ? -24.234 57.151  -25.55  1    116.61 ? 234 PHE D CZ  1 -0.222 0.524  -0.064 
ATOM   11192 N  N   . SER D 1 246 ? -17.647 60.836  -26.175 1    128.03 ? 235 SER D N   1 -0.162 0.558  -0.065 
ATOM   11193 C  CA  . SER D 1 246 ? -16.678 61.865  -25.795 1    126.16 ? 235 SER D CA  1 -0.153 0.567  -0.064 
ATOM   11194 C  C   . SER D 1 246 ? -16.903 63.194  -26.5   1    126.51 ? 235 SER D C   1 -0.155 0.579  -0.066 
ATOM   11195 O  O   . SER D 1 246 ? -16.299 64.198  -26.099 1    125.03 ? 235 SER D O   1 -0.149 0.588  -0.065 
ATOM   11196 C  CB  . SER D 1 246 ? -15.245 61.383  -26.063 1    125.67 ? 235 SER D CB  1 -0.14  0.563  -0.065 
ATOM   11197 O  OG  . SER D 1 246 ? -15.033 61.084  -27.424 1    123.06 ? 235 SER D OG  1 -0.138 0.56   -0.068 
ATOM   11198 N  N   . HIS D 1 247 ? -17.746 63.225  -27.537 1    127.88 ? 236 HIS D N   1 -0.163 0.579  -0.069 
ATOM   11199 C  CA  . HIS D 1 247 ? -18.165 64.505  -28.096 1    129.57 ? 236 HIS D CA  1 -0.166 0.591  -0.07  
ATOM   11200 C  C   . HIS D 1 247 ? -19.09  65.241  -27.129 1    127.4  ? 236 HIS D C   1 -0.175 0.598  -0.068 
ATOM   11201 O  O   . HIS D 1 247 ? -18.987 66.463  -26.973 1    128.32 ? 236 HIS D O   1 -0.174 0.609  -0.067 
ATOM   11202 C  CB  . HIS D 1 247 ? -18.824 64.297  -29.467 1    132.24 ? 236 HIS D CB  1 -0.173 0.589  -0.074 
ATOM   11203 C  CG  . HIS D 1 247 ? -20.245 63.821  -29.405 1    130.13 ? 236 HIS D CG  1 -0.186 0.585  -0.073 
ATOM   11204 N  ND1 . HIS D 1 247 ? -21.298 64.563  -29.898 1    127.59 ? 236 HIS D ND1 1 -0.195 0.592  -0.075 
ATOM   11205 C  CD2 . HIS D 1 247 ? -20.785 62.678  -28.918 1    129.22 ? 236 HIS D CD2 1 -0.19  0.574  -0.072 
ATOM   11206 C  CE1 . HIS D 1 247 ? -22.427 63.903  -29.71  1    125.7  ? 236 HIS D CE1 1 -0.206 0.586  -0.074 
ATOM   11207 N  NE2 . HIS D 1 247 ? -22.144 62.756  -29.117 1    128.89 ? 236 HIS D NE2 1 -0.203 0.575  -0.073 
ATOM   11208 N  N   . LEU D 1 248 ? -19.985 64.515  -26.459 1    127.97 ? 237 LEU D N   1 -0.183 0.591  -0.066 
ATOM   11209 C  CA  . LEU D 1 248 ? -20.706 65.088  -25.328 1    127.34 ? 237 LEU D CA  1 -0.19  0.596  -0.063 
ATOM   11210 C  C   . LEU D 1 248 ? -19.733 65.44   -24.206 1    124.96 ? 237 LEU D C   1 -0.181 0.6    -0.06  
ATOM   11211 O  O   . LEU D 1 248 ? -18.648 64.861  -24.087 1    125.94 ? 237 LEU D O   1 -0.171 0.594  -0.06  
ATOM   11212 C  CB  . LEU D 1 248 ? -21.765 64.107  -24.824 1    121.98 ? 237 LEU D CB  1 -0.199 0.587  -0.062 
ATOM   11213 C  CG  . LEU D 1 248 ? -23.019 63.948  -25.68  1    123.13 ? 237 LEU D CG  1 -0.211 0.586  -0.064 
ATOM   11214 C  CD1 . LEU D 1 248 ? -23.795 62.699  -25.29  1    123.35 ? 237 LEU D CD1 1 -0.218 0.575  -0.063 
ATOM   11215 C  CD2 . LEU D 1 248 ? -23.901 65.184  -25.56  1    118.32 ? 237 LEU D CD2 1 -0.219 0.597  -0.064 
ATOM   11216 N  N   . SER D 1 249 ? -20.123 66.406  -23.376 1    125.29 ? 238 SER D N   1 -0.184 0.609  -0.058 
ATOM   11217 C  CA  . SER D 1 249 ? -19.291 66.864  -22.264 1    130.86 ? 238 SER D CA  1 -0.177 0.613  -0.056 
ATOM   11218 C  C   . SER D 1 249 ? -19.755 66.198  -20.968 1    133.71 ? 238 SER D C   1 -0.181 0.607  -0.052 
ATOM   11219 O  O   . SER D 1 249 ? -20.935 66.277  -20.6   1    131.85 ? 238 SER D O   1 -0.192 0.607  -0.051 
ATOM   11220 C  CB  . SER D 1 249 ? -19.319 68.382  -22.135 1    131.21 ? 238 SER D CB  1 -0.177 0.627  -0.055 
ATOM   11221 O  OG  . SER D 1 249 ? -18.517 68.796  -21.037 1    123.96 ? 238 SER D OG  1 -0.17  0.63   -0.053 
ATOM   11222 N  N   . ILE D 1 250 ? -18.819 65.545  -20.28  1    132.13 ? 239 ILE D N   1 -0.172 0.601  -0.051 
ATOM   11223 C  CA  . ILE D 1 250 ? -19.129 64.595  -19.219 1    124.34 ? 239 ILE D CA  1 -0.175 0.592  -0.048 
ATOM   11224 C  C   . ILE D 1 250 ? -18.053 64.686  -18.143 1    128.09 ? 239 ILE D C   1 -0.165 0.593  -0.045 
ATOM   11225 O  O   . ILE D 1 250 ? -16.864 64.508  -18.436 1    122.68 ? 239 ILE D O   1 -0.155 0.591  -0.046 
ATOM   11226 C  CB  . ILE D 1 250 ? -19.211 63.147  -19.745 1    127.41 ? 239 ILE D CB  1 -0.176 0.579  -0.049 
ATOM   11227 C  CG1 . ILE D 1 250 ? -20.289 62.976  -20.817 1    129.47 ? 239 ILE D CG1 1 -0.186 0.577  -0.052 
ATOM   11228 C  CG2 . ILE D 1 250 ? -19.469 62.176  -18.617 1    126.36 ? 239 ILE D CG2 1 -0.178 0.57   -0.046 
ATOM   11229 C  CD1 . ILE D 1 250 ? -20.191 61.644  -21.534 1    127.74 ? 239 ILE D CD1 1 -0.185 0.565  -0.054 
ATOM   11230 N  N   . CYS D 1 251 ? -18.47  64.969  -16.91  1    131.52 ? 240 CYS D N   1 -0.169 0.595  -0.042 
ATOM   11231 C  CA  . CYS D 1 251 ? -17.691 64.659  -15.719 1    117.36 ? 240 CYS D CA  1 -0.162 0.593  -0.039 
ATOM   11232 C  C   . CYS D 1 251 ? -18.118 63.265  -15.267 1    116.17 ? 240 CYS D C   1 -0.166 0.58   -0.038 
ATOM   11233 O  O   . CYS D 1 251 ? -19.317 62.961  -15.243 1    115.36 ? 240 CYS D O   1 -0.177 0.577  -0.038 
ATOM   11234 C  CB  . CYS D 1 251 ? -17.937 65.714  -14.633 1    127.55 ? 240 CYS D CB  1 -0.164 0.602  -0.037 
ATOM   11235 S  SG  . CYS D 1 251 ? -16.923 65.683  -13.078 1    139.64 ? 240 CYS D SG  1 -0.155 0.602  -0.033 
ATOM   11236 N  N   . HIS D 1 252 ? -17.145 62.406  -14.962 1    115.79 ? 241 HIS D N   1 -0.157 0.572  -0.037 
ATOM   11237 C  CA  . HIS D 1 252 ? -17.421 61.017  -14.59  1    118.95 ? 241 HIS D CA  1 -0.16  0.559  -0.036 
ATOM   11238 C  C   . HIS D 1 252 ? -16.507 60.613  -13.436 1    121.66 ? 241 HIS D C   1 -0.151 0.555  -0.034 
ATOM   11239 O  O   . HIS D 1 252 ? -15.301 60.424  -13.634 1    121.66 ? 241 HIS D O   1 -0.14  0.554  -0.034 
ATOM   11240 C  CB  . HIS D 1 252 ? -17.237 60.088  -15.792 1    114.85 ? 241 HIS D CB  1 -0.158 0.551  -0.039 
ATOM   11241 C  CG  . HIS D 1 252 ? -17.472 58.64   -15.486 1    119.05 ? 241 HIS D CG  1 -0.16  0.537  -0.039 
ATOM   11242 N  ND1 . HIS D 1 252 ? -17.073 57.629  -16.333 1    120.27 ? 241 HIS D ND1 1 -0.156 0.528  -0.041 
ATOM   11243 C  CD2 . HIS D 1 252 ? -18.063 58.031  -14.428 1    123.49 ? 241 HIS D CD2 1 -0.166 0.532  -0.036 
ATOM   11244 C  CE1 . HIS D 1 252 ? -17.406 56.461  -15.811 1    119.47 ? 241 HIS D CE1 1 -0.16  0.517  -0.039 
ATOM   11245 N  NE2 . HIS D 1 252 ? -18.006 56.676  -14.654 1    120.79 ? 241 HIS D NE2 1 -0.165 0.519  -0.037 
ATOM   11246 N  N   . ILE D 1 253 ? -17.078 60.463  -12.241 1    119.12 ? 242 ILE D N   1 -0.157 0.554  -0.031 
ATOM   11247 C  CA  . ILE D 1 253 ? -16.34  60.049  -11.048 1    120.73 ? 242 ILE D CA  1 -0.15  0.55   -0.028 
ATOM   11248 C  C   . ILE D 1 253 ? -16.668 58.579  -10.811 1    115.24 ? 242 ILE D C   1 -0.153 0.537  -0.027 
ATOM   11249 O  O   . ILE D 1 253 ? -17.74  58.242  -10.294 1    111.63 ? 242 ILE D O   1 -0.163 0.534  -0.026 
ATOM   11250 C  CB  . ILE D 1 253 ? -16.687 60.907  -9.821  1    120.67 ? 242 ILE D CB  1 -0.153 0.558  -0.025 
ATOM   11251 C  CG1 . ILE D 1 253 ? -16.402 62.392  -10.078 1    120.11 ? 242 ILE D CG1 1 -0.15  0.572  -0.025 
ATOM   11252 C  CG2 . ILE D 1 253 ? -15.898 60.446  -8.587  1    115.87 ? 242 ILE D CG2 1 -0.146 0.554  -0.021 
ATOM   11253 C  CD1 . ILE D 1 253 ? -17.567 63.155  -10.664 1    120.02 ? 242 ILE D CD1 1 -0.161 0.579  -0.027 
ATOM   11254 N  N   . ASP D 1 254 ? -15.758 57.689  -11.198 1    111.3  ? 243 ASP D N   1 -0.144 0.529  -0.028 
ATOM   11255 C  CA  . ASP D 1 254 ? -15.901 56.274  -10.893 1    111.47 ? 243 ASP D CA  1 -0.146 0.516  -0.027 
ATOM   11256 C  C   . ASP D 1 254 ? -15.075 55.955  -9.657  1    112.48 ? 243 ASP D C   1 -0.138 0.513  -0.024 
ATOM   11257 O  O   . ASP D 1 254 ? -13.892 56.307  -9.575  1    110.71 ? 243 ASP D O   1 -0.127 0.516  -0.024 
ATOM   11258 C  CB  . ASP D 1 254 ? -15.481 55.379  -12.067 1    115.67 ? 243 ASP D CB  1 -0.142 0.508  -0.03  
ATOM   11259 C  CG  . ASP D 1 254 ? -15.63  53.876  -11.752 1    113.24 ? 243 ASP D CG  1 -0.143 0.494  -0.029 
ATOM   11260 O  OD1 . ASP D 1 254 ? -16.09  53.528  -10.638 1    122.07 ? 243 ASP D OD1 1 -0.147 0.491  -0.027 
ATOM   11261 O  OD2 . ASP D 1 254 ? -15.299 53.034  -12.609 1    106.41 ? 243 ASP D OD2 1 -0.14  0.486  -0.031 
ATOM   11262 N  N   . VAL D 1 255 ? -15.705 55.267  -8.711  1    114.21 ? 244 VAL D N   1 -0.144 0.506  -0.022 
ATOM   11263 C  CA  . VAL D 1 255 ? -15.125 54.944  -7.416  1    112.07 ? 244 VAL D CA  1 -0.139 0.504  -0.019 
ATOM   11264 C  C   . VAL D 1 255 ? -15.05  53.426  -7.324  1    110.67 ? 244 VAL D C   1 -0.138 0.49   -0.018 
ATOM   11265 O  O   . VAL D 1 255 ? -16.043 52.742  -7.601  1    112.97 ? 244 VAL D O   1 -0.147 0.483  -0.019 
ATOM   11266 C  CB  . VAL D 1 255 ? -15.985 55.547  -6.287  1    104.09 ? 244 VAL D CB  1 -0.146 0.509  -0.016 
ATOM   11267 C  CG1 . VAL D 1 255 ? -15.475 55.136  -4.976  1    107.31 ? 244 VAL D CG1 1 -0.142 0.505  -0.012 
ATOM   11268 C  CG2 . VAL D 1 255 ? -15.978 57.054  -6.397  1    98.41  ? 244 VAL D CG2 1 -0.146 0.523  -0.016 
ATOM   11269 N  N   . PHE D 1 256 ? -13.877 52.897  -6.987  1    103.99 ? 245 PHE D N   1 -0.127 0.485  -0.017 
ATOM   11270 C  CA  . PHE D 1 256 ? -13.733 51.448  -7.115  1    110.41 ? 245 PHE D CA  1 -0.126 0.471  -0.018 
ATOM   11271 C  C   . PHE D 1 256 ? -12.448 51.004  -6.432  1    110.35 ? 245 PHE D C   1 -0.114 0.467  -0.016 
ATOM   11272 O  O   . PHE D 1 256 ? -11.505 51.785  -6.274  1    112.7  ? 245 PHE D O   1 -0.105 0.475  -0.016 
ATOM   11273 C  CB  . PHE D 1 256 ? -13.763 50.996  -8.601  1    111.77 ? 245 PHE D CB  1 -0.126 0.467  -0.021 
ATOM   11274 C  CG  . PHE D 1 256 ? -12.483 51.283  -9.385  1    111.46 ? 245 PHE D CG  1 -0.114 0.47   -0.023 
ATOM   11275 C  CD1 . PHE D 1 256 ? -11.433 50.369  -9.37   1    117.17 ? 245 PHE D CD1 1 -0.105 0.462  -0.023 
ATOM   11276 C  CD2 . PHE D 1 256 ? -12.338 52.447  -10.145 1    105.81 ? 245 PHE D CD2 1 -0.113 0.481  -0.025 
ATOM   11277 C  CE1 . PHE D 1 256 ? -10.263 50.611  -10.067 1    118.93 ? 245 PHE D CE1 1 -0.094 0.464  -0.025 
ATOM   11278 C  CE2 . PHE D 1 256 ? -11.159 52.693  -10.841 1    108.64 ? 245 PHE D CE2 1 -0.102 0.483  -0.027 
ATOM   11279 C  CZ  . PHE D 1 256 ? -10.126 51.77   -10.803 1    115.29 ? 245 PHE D CZ  1 -0.093 0.474  -0.027 
ATOM   11280 N  N   . ASP D 1 257 ? -12.426 49.736  -6.044  1    108.79 ? 246 ASP D N   1 -0.114 0.456  -0.015 
ATOM   11281 C  CA  . ASP D 1 257 ? -11.248 49.104  -5.466  1    117.73 ? 246 ASP D CA  1 -0.103 0.45   -0.014 
ATOM   11282 C  C   . ASP D 1 257 ? -10.582 48.244  -6.537  1    118.58 ? 246 ASP D C   1 -0.097 0.442  -0.016 
ATOM   11283 O  O   . ASP D 1 257 ? -11.152 47.238  -6.978  1    114.98 ? 246 ASP D O   1 -0.102 0.433  -0.017 
ATOM   11284 C  CB  . ASP D 1 257 ? -11.633 48.259  -4.246  1    117.59 ? 246 ASP D CB  1 -0.107 0.442  -0.011 
ATOM   11285 C  CG  . ASP D 1 257 ? -10.443 47.917  -3.349  1    121.77 ? 246 ASP D CG  1 -0.096 0.439  -0.008 
ATOM   11286 O  OD1 . ASP D 1 257 ? -9.283  48.033  -3.8    1    121.69 ? 246 ASP D OD1 1 -0.085 0.44   -0.009 
ATOM   11287 O  OD2 . ASP D 1 257 ? -10.672 47.521  -2.181  1    128.71 ? 246 ASP D OD2 1 -0.098 0.435  -0.005 
ATOM   11288 N  N   . SER D 1 258 ? -9.368  48.632  -6.937  1    123.13 ? 247 SER D N   1 -0.086 0.446  -0.017 
ATOM   11289 C  CA  . SER D 1 258 ? -8.653  47.936  -8.004  1    123.87 ? 247 SER D CA  1 -0.079 0.439  -0.02  
ATOM   11290 C  C   . SER D 1 258 ? -8.18   46.544  -7.602  1    124.34 ? 247 SER D C   1 -0.075 0.427  -0.019 
ATOM   11291 O  O   . SER D 1 258 ? -7.711  45.798  -8.471  1    130.53 ? 247 SER D O   1 -0.071 0.42   -0.021 
ATOM   11292 C  CB  . SER D 1 258 ? -7.449  48.76   -8.46   1    119.98 ? 247 SER D CB  1 -0.068 0.447  -0.021 
ATOM   11293 O  OG  . SER D 1 258 ? -6.42   48.727  -7.477  1    123.71 ? 247 SER D OG  1 -0.059 0.447  -0.019 
ATOM   11294 N  N   . ARG D 1 259 ? -8.272  46.18   -6.324  1    121.73 ? 248 ARG D N   1 -0.076 0.423  -0.016 
ATOM   11295 C  CA  . ARG D 1 259 ? -7.883  44.845  -5.889  1    126.04 ? 248 ARG D CA  1 -0.072 0.411  -0.015 
ATOM   11296 C  C   . ARG D 1 259 ? -8.965  43.808  -6.157  1    124.29 ? 248 ARG D C   1 -0.082 0.401  -0.015 
ATOM   11297 O  O   . ARG D 1 259 ? -8.675  42.605  -6.122  1    125    ? 248 ARG D O   1 -0.079 0.39   -0.015 
ATOM   11298 C  CB  . ARG D 1 259 ? -7.537  44.839  -4.388  1    127.43 ? 248 ARG D CB  1 -0.069 0.411  -0.011 
ATOM   11299 C  CG  . ARG D 1 259 ? -6.877  46.116  -3.877  1    123.52 ? 248 ARG D CG  1 -0.063 0.423  -0.01  
ATOM   11300 C  CD  . ARG D 1 259 ? -6.09   45.917  -2.574  1    135.02 ? 248 ARG D CD  1 -0.056 0.421  -0.006 
ATOM   11301 N  NE  . ARG D 1 259 ? -6.906  45.655  -1.391  1    134.74 ? 248 ARG D NE  1 -0.063 0.418  -0.003 
ATOM   11302 C  CZ  . ARG D 1 259 ? -7.761  46.518  -0.852  1    135.25 ? 248 ARG D CZ  1 -0.071 0.426  -0.002 
ATOM   11303 N  NH1 . ARG D 1 259 ? -8.048  47.669  -1.435  1    134.57 ? 248 ARG D NH1 1 -0.074 0.437  -0.004 
ATOM   11304 N  NH2 . ARG D 1 259 ? -8.35   46.216  0.3     1    131.05 ? 248 ARG D NH2 1 -0.077 0.424  0.001  
ATOM   11305 N  N   . VAL D 1 260 ? -10.201 44.245  -6.407  1    120.75 ? 249 VAL D N   1 -0.093 0.405  -0.016 
ATOM   11306 C  CA  . VAL D 1 260 ? -11.318 43.333  -6.619  1    123.24 ? 249 VAL D CA  1 -0.104 0.397  -0.017 
ATOM   11307 C  C   . VAL D 1 260 ? -11.809 43.511  -8.047  1    120.76 ? 249 VAL D C   1 -0.108 0.399  -0.02  
ATOM   11308 O  O   . VAL D 1 260 ? -11.313 44.376  -8.776  1    120.32 ? 249 VAL D O   1 -0.104 0.407  -0.022 
ATOM   11309 C  CB  . VAL D 1 260 ? -12.438 43.571  -5.587  1    119    ? 249 VAL D CB  1 -0.114 0.399  -0.014 
ATOM   11310 C  CG1 . VAL D 1 260 ? -11.833 43.692  -4.195  1    128.26 ? 249 VAL D CG1 1 -0.108 0.4    -0.01  
ATOM   11311 C  CG2 . VAL D 1 260 ? -13.257 44.81   -5.925  1    113.3  ? 249 VAL D CG2 1 -0.121 0.411  -0.015 
ATOM   11312 N  N   . TYR D 1 261 ? -12.774 42.692  -8.449  1    120.56 ? 250 TYR D N   1 -0.117 0.391  -0.021 
ATOM   11313 C  CA  . TYR D 1 261 ? -13.237 42.66   -9.83   1    121.22 ? 250 TYR D CA  1 -0.121 0.391  -0.025 
ATOM   11314 C  C   . TYR D 1 261 ? -13.569 44.072  -10.313 1    121.8  ? 250 TYR D C   1 -0.124 0.404  -0.026 
ATOM   11315 O  O   . TYR D 1 261 ? -14.044 44.901  -9.52   1    118.5  ? 250 TYR D O   1 -0.129 0.411  -0.024 
ATOM   11316 C  CB  . TYR D 1 261 ? -14.467 41.754  -9.93   1    119.12 ? 250 TYR D CB  1 -0.133 0.383  -0.025 
ATOM   11317 C  CG  . TYR D 1 261 ? -15.018 41.538  -11.31  1    114.34 ? 250 TYR D CG  1 -0.138 0.381  -0.028 
ATOM   11318 C  CD1 . TYR D 1 261 ? -15.938 42.421  -11.86  1    112.53 ? 250 TYR D CD1 1 -0.146 0.389  -0.03  
ATOM   11319 C  CD2 . TYR D 1 261 ? -14.642 40.428  -12.051 1    122.18 ? 250 TYR D CD2 1 -0.134 0.37   -0.03  
ATOM   11320 C  CE1 . TYR D 1 261 ? -16.459 42.208  -13.124 1    120.25 ? 250 TYR D CE1 1 -0.151 0.387  -0.033 
ATOM   11321 C  CE2 . TYR D 1 261 ? -15.153 40.197  -13.321 1    121.56 ? 250 TYR D CE2 1 -0.139 0.368  -0.033 
ATOM   11322 C  CZ  . TYR D 1 261 ? -16.063 41.089  -13.858 1    122.62 ? 250 TYR D CZ  1 -0.147 0.377  -0.035 
ATOM   11323 O  OH  . TYR D 1 261 ? -16.573 40.86   -15.121 1    116.51 ? 250 TYR D OH  1 -0.152 0.374  -0.038 
ATOM   11324 N  N   . PRO D 1 262 ? -13.287 44.405  -11.587 1    121.91 ? 251 PRO D N   1 -0.122 0.407  -0.029 
ATOM   11325 C  CA  . PRO D 1 262 ? -12.614 43.595  -12.614 1    119.88 ? 251 PRO D CA  1 -0.116 0.4    -0.031 
ATOM   11326 C  C   . PRO D 1 262 ? -11.085 43.622  -12.559 1    119.89 ? 251 PRO D C   1 -0.102 0.4    -0.031 
ATOM   11327 O  O   . PRO D 1 262 ? -10.451 43.498  -13.589 1    122.09 ? 251 PRO D O   1 -0.096 0.399  -0.034 
ATOM   11328 C  CB  . PRO D 1 262 ? -13.102 44.246  -13.911 1    116.93 ? 251 PRO D CB  1 -0.12  0.405  -0.035 
ATOM   11329 C  CG  . PRO D 1 262 ? -13.16  45.7    -13.544 1    115.64 ? 251 PRO D CG  1 -0.121 0.419  -0.034 
ATOM   11330 C  CD  . PRO D 1 262 ? -13.722 45.702  -12.139 1    118.76 ? 251 PRO D CD  1 -0.126 0.419  -0.03  
ATOM   11331 N  N   . GLN D 1 263 ? -10.447 43.813  -11.4   1    124.59 ? 252 GLN D N   1 -0.096 0.402  -0.028 
ATOM   11332 C  CA  . GLN D 1 263 ? -8.995  43.764  -11.229 1    123.71 ? 252 GLN D CA  1 -0.082 0.401  -0.028 
ATOM   11333 C  C   . GLN D 1 263 ? -8.254  44.838  -12.021 1    124.14 ? 252 GLN D C   1 -0.076 0.411  -0.03  
ATOM   11334 O  O   . GLN D 1 263 ? -7.02   44.917  -11.918 1    125.21 ? 252 GLN D O   1 -0.064 0.412  -0.03  
ATOM   11335 C  CB  . GLN D 1 263 ? -8.421  42.391  -11.614 1    129.22 ? 252 GLN D CB  1 -0.077 0.388  -0.029 
ATOM   11336 C  CG  . GLN D 1 263 ? -9.097  41.202  -10.931 1    126.83 ? 252 GLN D CG  1 -0.083 0.378  -0.027 
ATOM   11337 C  CD  . GLN D 1 263 ? -8.576  40.971  -9.522  1    129.57 ? 252 GLN D CD  1 -0.079 0.375  -0.024 
ATOM   11338 O  OE1 . GLN D 1 263 ? -7.941  41.85   -8.932  1    132.35 ? 252 GLN D OE1 1 -0.073 0.384  -0.022 
ATOM   11339 N  NE2 . GLN D 1 263 ? -8.834  39.783  -8.978  1    129.74 ? 252 GLN D NE2 1 -0.081 0.365  -0.022 
ATOM   11340 N  N   . GLN D 1 264 ? -8.942  45.656  -12.818 1    122.93 ? 253 GLN D N   1 -0.082 0.418  -0.032 
ATOM   11341 C  CA  . GLN D 1 264 ? -8.3    46.698  -13.618 1    122.55 ? 253 GLN D CA  1 -0.076 0.428  -0.034 
ATOM   11342 C  C   . GLN D 1 264 ? -7.907  47.85   -12.703 1    123.58 ? 253 GLN D C   1 -0.072 0.439  -0.032 
ATOM   11343 O  O   . GLN D 1 264 ? -8.775  48.513  -12.123 1    122.43 ? 253 GLN D O   1 -0.08  0.445  -0.03  
ATOM   11344 C  CB  . GLN D 1 264 ? -9.235  47.191  -14.715 1    116.29 ? 253 GLN D CB  1 -0.085 0.432  -0.037 
ATOM   11345 C  CG  . GLN D 1 264 ? -10.008 46.093  -15.389 1    119.04 ? 253 GLN D CG  1 -0.092 0.422  -0.038 
ATOM   11346 C  CD  . GLN D 1 264 ? -11.2   46.624  -16.155 1    122.87 ? 253 GLN D CD  1 -0.103 0.427  -0.04  
ATOM   11347 O  OE1 . GLN D 1 264 ? -11.572 47.793  -16.013 1    122.7  ? 253 GLN D OE1 1 -0.106 0.438  -0.04  
ATOM   11348 N  NE2 . GLN D 1 264 ? -11.81  45.769  -16.974 1    120.27 ? 253 GLN D NE2 1 -0.108 0.419  -0.042 
ATOM   11349 N  N   . ASP D 1 265 ? -6.603  48.098  -12.575 1    122.5  ? 254 ASP D N   1 -0.061 0.441  -0.031 
ATOM   11350 C  CA  . ASP D 1 265 ? -6.107  49.17   -11.731 1    124.04 ? 254 ASP D CA  1 -0.056 0.451  -0.029 
ATOM   11351 C  C   . ASP D 1 265 ? -5.859  50.415  -12.584 1    127.29 ? 254 ASP D C   1 -0.054 0.462  -0.031 
ATOM   11352 O  O   . ASP D 1 265 ? -6.402  50.541  -13.689 1    131.63 ? 254 ASP D O   1 -0.059 0.463  -0.034 
ATOM   11353 C  CB  . ASP D 1 265 ? -4.857  48.707  -10.965 1    124.41 ? 254 ASP D CB  1 -0.045 0.446  -0.027 
ATOM   11354 C  CG  . ASP D 1 265 ? -3.638  48.552  -11.855 1    125.93 ? 254 ASP D CG  1 -0.033 0.445  -0.03  
ATOM   11355 O  OD1 . ASP D 1 265 ? -3.074  49.579  -12.291 1    123.85 ? 254 ASP D OD1 1 -0.028 0.454  -0.031 
ATOM   11356 O  OD2 . ASP D 1 265 ? -3.232  47.399  -12.096 1    128.1  ? 254 ASP D OD2 1 -0.03  0.434  -0.03  
ATOM   11357 N  N   . PHE D 1 266 ? -5.038  51.342  -12.075 1    126.01 ? 255 PHE D N   1 -0.046 0.471  -0.03  
ATOM   11358 C  CA  . PHE D 1 266 ? -4.75   52.573  -12.809 1    132.63 ? 255 PHE D CA  1 -0.044 0.482  -0.032 
ATOM   11359 C  C   . PHE D 1 266 ? -4.027  52.284  -14.12  1    136.42 ? 255 PHE D C   1 -0.037 0.479  -0.035 
ATOM   11360 O  O   . PHE D 1 266 ? -4.291  52.932  -15.143 1    136.65 ? 255 PHE D O   1 -0.039 0.485  -0.038 
ATOM   11361 C  CB  . PHE D 1 266 ? -3.908  53.515  -11.948 1    135.37 ? 255 PHE D CB  1 -0.036 0.49   -0.03  
ATOM   11362 C  CG  . PHE D 1 266 ? -4.674  54.208  -10.856 1    134.88 ? 255 PHE D CG  1 -0.043 0.497  -0.027 
ATOM   11363 C  CD1 . PHE D 1 266 ? -5.791  54.984  -11.15  1    133.29 ? 255 PHE D CD1 1 -0.053 0.504  -0.028 
ATOM   11364 C  CD2 . PHE D 1 266 ? -4.255  54.11   -9.536  1    134.39 ? 255 PHE D CD2 1 -0.039 0.496  -0.024 
ATOM   11365 C  CE1 . PHE D 1 266 ? -6.484  55.639  -10.141 1    136.42 ? 255 PHE D CE1 1 -0.059 0.51   -0.025 
ATOM   11366 C  CE2 . PHE D 1 266 ? -4.945  54.762  -8.518  1    134.62 ? 255 PHE D CE2 1 -0.045 0.502  -0.021 
ATOM   11367 C  CZ  . PHE D 1 266 ? -6.059  55.529  -8.819  1    133.79 ? 255 PHE D CZ  1 -0.056 0.509  -0.022 
ATOM   11368 N  N   . ALA D 1 267 ? -3.106  51.313  -14.105 1    137.1  ? 256 ALA D N   1 -0.028 0.47   -0.035 
ATOM   11369 C  CA  . ALA D 1 267 ? -2.299  51.02   -15.289 1    134.37 ? 256 ALA D CA  1 -0.021 0.468  -0.038 
ATOM   11370 C  C   . ALA D 1 267 ? -3.166  50.568  -16.457 1    129.89 ? 256 ALA D C   1 -0.029 0.463  -0.041 
ATOM   11371 O  O   . ALA D 1 267 ? -3.053  51.101  -17.561 1    131.39 ? 256 ALA D O   1 -0.028 0.468  -0.044 
ATOM   11372 C  CB  . ALA D 1 267 ? -1.248  49.964  -14.955 1    129.73 ? 256 ALA D CB  1 -0.011 0.458  -0.037 
ATOM   11373 N  N   . TYR D 1 268 ? -4.033  49.575  -16.231 1    129.72 ? 257 TYR D N   1 -0.037 0.454  -0.041 
ATOM   11374 C  CA  . TYR D 1 268 ? -4.951  49.133  -17.275 1    127.32 ? 257 TYR D CA  1 -0.045 0.45   -0.043 
ATOM   11375 C  C   . TYR D 1 268 ? -5.709  50.305  -17.881 1    132.41 ? 257 TYR D C   1 -0.052 0.461  -0.045 
ATOM   11376 O  O   . TYR D 1 268 ? -6.009  50.301  -19.082 1    134.87 ? 257 TYR D O   1 -0.055 0.461  -0.048 
ATOM   11377 C  CB  . TYR D 1 268 ? -5.932  48.103  -16.705 1    126.22 ? 257 TYR D CB  1 -0.054 0.441  -0.042 
ATOM   11378 C  CG  . TYR D 1 268 ? -6.903  47.482  -17.703 1    124.82 ? 257 TYR D CG  1 -0.063 0.435  -0.044 
ATOM   11379 C  CD1 . TYR D 1 268 ? -8.018  48.186  -18.165 1    125.29 ? 257 TYR D CD1 1 -0.073 0.442  -0.045 
ATOM   11380 C  CD2 . TYR D 1 268 ? -6.729  46.178  -18.141 1    121.76 ? 257 TYR D CD2 1 -0.062 0.423  -0.045 
ATOM   11381 C  CE1 . TYR D 1 268 ? -8.912  47.618  -19.052 1    122.68 ? 257 TYR D CE1 1 -0.082 0.436  -0.048 
ATOM   11382 C  CE2 . TYR D 1 268 ? -7.62   45.6    -19.022 1    123.67 ? 257 TYR D CE2 1 -0.07  0.418  -0.047 
ATOM   11383 C  CZ  . TYR D 1 268 ? -8.709  46.324  -19.478 1    127.07 ? 257 TYR D CZ  1 -0.08  0.425  -0.049 
ATOM   11384 O  OH  . TYR D 1 268 ? -9.594  45.747  -20.365 1    133.85 ? 257 TYR D OH  1 -0.088 0.419  -0.051 
ATOM   11385 N  N   . ILE D 1 269 ? -6.021  51.322  -17.074 1    134.38 ? 258 ILE D N   1 -0.055 0.47   -0.043 
ATOM   11386 C  CA  . ILE D 1 269 ? -6.712  52.48   -17.619 1    134.67 ? 258 ILE D CA  1 -0.062 0.481  -0.044 
ATOM   11387 C  C   . ILE D 1 269 ? -5.783  53.299  -18.497 1    138.85 ? 258 ILE D C   1 -0.053 0.488  -0.046 
ATOM   11388 O  O   . ILE D 1 269 ? -6.253  54.024  -19.383 1    139.72 ? 258 ILE D O   1 -0.057 0.495  -0.048 
ATOM   11389 C  CB  . ILE D 1 269 ? -7.318  53.343  -16.499 1    132.94 ? 258 ILE D CB  1 -0.067 0.489  -0.041 
ATOM   11390 C  CG1 . ILE D 1 269 ? -7.998  52.438  -15.457 1    128.93 ? 258 ILE D CG1 1 -0.073 0.481  -0.039 
ATOM   11391 C  CG2 . ILE D 1 269 ? -8.301  54.356  -17.093 1    126.85 ? 258 ILE D CG2 1 -0.076 0.498  -0.043 
ATOM   11392 C  CD1 . ILE D 1 269 ? -8.84   53.162  -14.441 1    122.12 ? 258 ILE D CD1 1 -0.081 0.487  -0.036 
ATOM   11393 N  N   . ASN D 1 270 ? -4.468  53.178  -18.298 1    140.75 ? 259 ASN D N   1 -0.041 0.487  -0.046 
ATOM   11394 C  CA  . ASN D 1 270 ? -3.527  53.915  -19.136 1    143.48 ? 259 ASN D CA  1 -0.032 0.494  -0.048 
ATOM   11395 C  C   . ASN D 1 270 ? -3.563  53.416  -20.583 1    143.29 ? 259 ASN D C   1 -0.033 0.49   -0.051 
ATOM   11396 O  O   . ASN D 1 270 ? -3.917  54.172  -21.494 1    141.34 ? 259 ASN D O   1 -0.036 0.496  -0.054 
ATOM   11397 C  CB  . ASN D 1 270 ? -2.116  53.838  -18.543 1    144.18 ? 259 ASN D CB  1 -0.019 0.493  -0.046 
ATOM   11398 C  CG  . ASN D 1 270 ? -1.981  54.617  -17.234 1    142.9  ? 259 ASN D CG  1 -0.018 0.501  -0.043 
ATOM   11399 O  OD1 . ASN D 1 270 ? -1.366  55.684  -17.19  1    145.12 ? 259 ASN D OD1 1 -0.013 0.51   -0.043 
ATOM   11400 N  ND2 . ASN D 1 270 ? -2.568  54.089  -16.168 1    139.02 ? 259 ASN D ND2 1 -0.024 0.496  -0.04  
ATOM   11401 N  N   . ASN D 1 271 ? -3.231  52.137  -20.818 1    139.81 ? 260 ASN D N   1 -0.03  0.478  -0.052 
ATOM   11402 C  CA  . ASN D 1 271 ? -3.177  51.662  -22.201 1    145.84 ? 260 ASN D CA  1 -0.029 0.473  -0.055 
ATOM   11403 C  C   . ASN D 1 271 ? -4.54   51.701  -22.882 1    143.85 ? 260 ASN D C   1 -0.042 0.474  -0.057 
ATOM   11404 O  O   . ASN D 1 271 ? -4.612  51.804  -24.113 1    146.86 ? 260 ASN D O   1 -0.042 0.475  -0.06  
ATOM   11405 C  CB  . ASN D 1 271 ? -2.614  50.242  -22.299 1    145.85 ? 260 ASN D CB  1 -0.024 0.46   -0.056 
ATOM   11406 C  CG  . ASN D 1 271 ? -2.601  49.727  -23.748 1    150.38 ? 260 ASN D CG  1 -0.024 0.456  -0.059 
ATOM   11407 O  OD1 . ASN D 1 271 ? -3.486  48.967  -24.16  1    146.96 ? 260 ASN D OD1 1 -0.032 0.449  -0.06  
ATOM   11408 N  ND2 . ASN D 1 271 ? -1.621  50.18   -24.533 1    144.43 ? 260 ASN D ND2 1 -0.015 0.46   -0.061 
ATOM   11409 N  N   . GLU D 1 272 ? -5.63   51.607  -22.121 1    142.46 ? 261 GLU D N   1 -0.052 0.473  -0.055 
ATOM   11410 C  CA  . GLU D 1 272 ? -6.938  51.7    -22.757 1    141.92 ? 261 GLU D CA  1 -0.064 0.474  -0.057 
ATOM   11411 C  C   . GLU D 1 272 ? -7.359  53.143  -23.016 1    139.84 ? 261 GLU D C   1 -0.067 0.487  -0.057 
ATOM   11412 O  O   . GLU D 1 272 ? -8.305  53.369  -23.778 1    134.38 ? 261 GLU D O   1 -0.076 0.489  -0.059 
ATOM   11413 C  CB  . GLU D 1 272 ? -7.994  50.964  -21.921 1    140.81 ? 261 GLU D CB  1 -0.073 0.467  -0.055 
ATOM   11414 C  CG  . GLU D 1 272 ? -7.741  49.447  -21.759 1    139.7  ? 261 GLU D CG  1 -0.071 0.453  -0.054 
ATOM   11415 C  CD  . GLU D 1 272 ? -7.567  48.671  -23.087 1    149.16 ? 261 GLU D CD  1 -0.069 0.446  -0.058 
ATOM   11416 O  OE1 . GLU D 1 272 ? -7.821  49.22   -24.189 1    148.32 ? 261 GLU D OE1 1 -0.072 0.451  -0.06  
ATOM   11417 O  OE2 . GLU D 1 272 ? -7.172  47.485  -23.017 1    148.87 ? 261 GLU D OE2 1 -0.066 0.435  -0.057 
ATOM   11418 N  N   . PHE D 1 273 ? -6.679  54.113  -22.406 1    143.29 ? 262 PHE D N   1 -0.061 0.496  -0.056 
ATOM   11419 C  CA  . PHE D 1 273 ? -6.81   55.523  -22.745 1    142.47 ? 262 PHE D CA  1 -0.062 0.509  -0.057 
ATOM   11420 C  C   . PHE D 1 273 ? -5.581  56.033  -23.494 1    141.05 ? 262 PHE D C   1 -0.051 0.513  -0.059 
ATOM   11421 O  O   . PHE D 1 273 ? -5.479  57.244  -23.739 1    137.22 ? 262 PHE D O   1 -0.05  0.525  -0.059 
ATOM   11422 C  CB  . PHE D 1 273 ? -7.043  56.363  -21.473 1    142.27 ? 262 PHE D CB  1 -0.065 0.517  -0.054 
ATOM   11423 C  CG  . PHE D 1 273 ? -8.516  56.59   -21.116 1    138.12 ? 262 PHE D CG  1 -0.078 0.519  -0.053 
ATOM   11424 C  CD1 . PHE D 1 273 ? -9.264  55.603  -20.482 1    135.73 ? 262 PHE D CD1 1 -0.085 0.51   -0.051 
ATOM   11425 C  CD2 . PHE D 1 273 ? -9.13   57.816  -21.377 1    134.01 ? 262 PHE D CD2 1 -0.084 0.53   -0.053 
ATOM   11426 C  CE1 . PHE D 1 273 ? -10.604 55.825  -20.147 1    132.44 ? 262 PHE D CE1 1 -0.097 0.512  -0.05  
ATOM   11427 C  CE2 . PHE D 1 273 ? -10.468 58.042  -21.041 1    128.1  ? 262 PHE D CE2 1 -0.096 0.532  -0.053 
ATOM   11428 C  CZ  . PHE D 1 273 ? -11.203 57.047  -20.432 1    126.63 ? 262 PHE D CZ  1 -0.103 0.523  -0.051 
ATOM   11429 N  N   . ASN D 1 274 ? -4.692  55.116  -23.928 1    145.55 ? 263 ASN D N   1 -0.043 0.505  -0.06  
ATOM   11430 C  CA  . ASN D 1 274 ? -3.252  55.316  -24.159 1    147.2  ? 263 ASN D CA  1 -0.03  0.507  -0.06  
ATOM   11431 C  C   . ASN D 1 274 ? -2.81   56.744  -23.86  1    145.42 ? 263 ASN D C   1 -0.026 0.52   -0.06  
ATOM   11432 O  O   . ASN D 1 274 ? -2.32   57.47   -24.732 1    146.98 ? 263 ASN D O   1 -0.021 0.527  -0.062 
ATOM   11433 C  CB  . ASN D 1 274 ? -2.804  54.875  -25.574 1    147.18 ? 263 ASN D CB  1 -0.026 0.503  -0.064 
ATOM   11434 C  CG  . ASN D 1 274 ? -3.795  55.223  -26.678 1    144.88 ? 263 ASN D CG  1 -0.035 0.506  -0.067 
ATOM   11435 O  OD1 . ASN D 1 274 ? -4.959  54.82   -26.645 1    148.31 ? 263 ASN D OD1 1 -0.045 0.502  -0.067 
ATOM   11436 N  ND2 . ASN D 1 274 ? -3.314  55.942  -27.689 1    132.09 ? 263 ASN D ND2 1 -0.03  0.513  -0.069 
ATOM   11437 N  N   . SER D 1 275 ? -2.997  57.138  -22.606 1    141.84 ? 264 SER D N   1 -0.027 0.524  -0.056 
ATOM   11438 C  CA  . SER D 1 275 ? -2.558  58.42   -22.091 1    144.12 ? 264 SER D CA  1 -0.023 0.535  -0.055 
ATOM   11439 C  C   . SER D 1 275 ? -2.317  58.228  -20.606 1    144.27 ? 264 SER D C   1 -0.021 0.534  -0.051 
ATOM   11440 O  O   . SER D 1 275 ? -3.026  57.455  -19.958 1    145.78 ? 264 SER D O   1 -0.028 0.527  -0.05  
ATOM   11441 C  CB  . SER D 1 275 ? -3.598  59.52   -22.33  1    144.22 ? 264 SER D CB  1 -0.033 0.545  -0.056 
ATOM   11442 O  OG  . SER D 1 275 ? -4.412  59.706  -21.185 1    138.33 ? 264 SER D OG  1 -0.04  0.547  -0.053 
ATOM   11443 N  N   . GLU D 1 276 ? -1.301  58.895  -20.077 1    143.87 ? 265 GLU D N   1 -0.012 0.54   -0.05  
ATOM   11444 C  CA  . GLU D 1 276 ? -1.075  58.845  -18.644 1    146.43 ? 265 GLU D CA  1 -0.01  0.539  -0.047 
ATOM   11445 C  C   . GLU D 1 276 ? -1.956  59.891  -17.975 1    150.69 ? 265 GLU D C   1 -0.018 0.549  -0.045 
ATOM   11446 O  O   . GLU D 1 276 ? -2.069  61.025  -18.458 1    151.01 ? 265 GLU D O   1 -0.019 0.559  -0.046 
ATOM   11447 C  CB  . GLU D 1 276 ? 0.4     59.06   -18.302 1    145.02 ? 265 GLU D CB  1 0.004  0.541  -0.046 
ATOM   11448 C  CG  . GLU D 1 276 ? 1.234   57.793  -18.483 1    145    ? 265 GLU D CG  1 0.011  0.53   -0.046 
ATOM   11449 C  CD  . GLU D 1 276 ? 2.619   57.878  -17.867 1    149.32 ? 265 GLU D CD  1 0.024  0.53   -0.045 
ATOM   11450 O  OE1 . GLU D 1 276 ? 2.738   58.333  -16.705 1    152.6  ? 265 GLU D OE1 1 0.025  0.535  -0.042 
ATOM   11451 O  OE2 . GLU D 1 276 ? 3.586   57.475  -18.551 1    147.2  ? 265 GLU D OE2 1 0.033  0.527  -0.046 
ATOM   11452 N  N   . GLY D 1 277 ? -2.618  59.486  -16.894 1    147.55 ? 266 GLY D N   1 -0.024 0.545  -0.042 
ATOM   11453 C  CA  . GLY D 1 277 ? -3.42   60.416  -16.135 1    144.29 ? 266 GLY D CA  1 -0.031 0.554  -0.04  
ATOM   11454 C  C   . GLY D 1 277 ? -2.559  61.255  -15.213 1    143.12 ? 266 GLY D C   1 -0.023 0.561  -0.038 
ATOM   11455 O  O   . GLY D 1 277 ? -1.457  60.863  -14.827 1    143.92 ? 266 GLY D O   1 -0.013 0.558  -0.037 
ATOM   11456 N  N   . VAL D 1 278 ? -3.06   62.434  -14.878 1    141.42 ? 267 VAL D N   1 -0.028 0.572  -0.037 
ATOM   11457 C  CA  . VAL D 1 278 ? -2.388  63.306  -13.927 1    144.48 ? 267 VAL D CA  1 -0.022 0.58   -0.035 
ATOM   11458 C  C   . VAL D 1 278 ? -3.059  63.124  -12.571 1    147.5  ? 267 VAL D C   1 -0.028 0.578  -0.031 
ATOM   11459 O  O   . VAL D 1 278 ? -4.285  62.959  -12.484 1    148.11 ? 267 VAL D O   1 -0.039 0.577  -0.031 
ATOM   11460 C  CB  . VAL D 1 278 ? -2.405  64.776  -14.401 1    144.72 ? 267 VAL D CB  1 -0.022 0.594  -0.036 
ATOM   11461 C  CG1 . VAL D 1 278 ? -3.72   65.484  -14.046 1    142.68 ? 267 VAL D CG1 1 -0.034 0.6    -0.035 
ATOM   11462 C  CG2 . VAL D 1 278 ? -1.181  65.529  -13.865 1    143.44 ? 267 VAL D CG2 1 -0.011 0.601  -0.035 
ATOM   11463 N  N   . ASP D 1 279 ? -2.252  63.083  -11.513 1    144.88 ? 268 ASP D N   1 -0.021 0.578  -0.029 
ATOM   11464 C  CA  . ASP D 1 279 ? -2.77   62.883  -10.159 1    143.17 ? 268 ASP D CA  1 -0.025 0.576  -0.025 
ATOM   11465 C  C   . ASP D 1 279 ? -3.151  64.249  -9.615  1    145.5  ? 268 ASP D C   1 -0.029 0.589  -0.024 
ATOM   11466 O  O   . ASP D 1 279 ? -2.318  64.964  -9.062  1    151.84 ? 268 ASP D O   1 -0.021 0.595  -0.023 
ATOM   11467 C  CB  . ASP D 1 279 ? -1.727  62.199  -9.273  1    142.06 ? 268 ASP D CB  1 -0.016 0.57   -0.023 
ATOM   11468 C  CG  . ASP D 1 279 ? -2.159  62.094  -7.796  1    146.65 ? 268 ASP D CG  1 -0.02  0.569  -0.019 
ATOM   11469 O  OD1 . ASP D 1 279 ? -2.344  63.137  -7.124  1    145.57 ? 268 ASP D OD1 1 -0.021 0.579  -0.018 
ATOM   11470 O  OD2 . ASP D 1 279 ? -2.305  60.956  -7.293  1    144.74 ? 268 ASP D OD2 1 -0.021 0.559  -0.018 
ATOM   11471 N  N   . ILE D 1 280 ? -4.425  64.638  -9.76   1    143.25 ? 269 ILE D N   1 -0.041 0.592  -0.024 
ATOM   11472 C  CA  . ILE D 1 280 ? -4.783  65.942  -9.206  1    150.77 ? 269 ILE D CA  1 -0.044 0.604  -0.023 
ATOM   11473 C  C   . ILE D 1 280 ? -4.882  65.871  -7.68   1    145.87 ? 269 ILE D C   1 -0.045 0.604  -0.019 
ATOM   11474 O  O   . ILE D 1 280 ? -4.78   66.907  -7.006  1    148.57 ? 269 ILE D O   1 -0.044 0.613  -0.017 
ATOM   11475 C  CB  . ILE D 1 280 ? -6.05   66.529  -9.892  1    147.61 ? 269 ILE D CB  1 -0.055 0.61   -0.025 
ATOM   11476 C  CG1 . ILE D 1 280 ? -6.645  67.721  -9.111  1    143.89 ? 269 ILE D CG1 1 -0.061 0.621  -0.023 
ATOM   11477 C  CG2 . ILE D 1 280 ? -7.082  65.451  -10.24  1    133.98 ? 269 ILE D CG2 1 -0.065 0.6    -0.026 
ATOM   11478 C  CD1 . ILE D 1 280 ? -5.817  68.987  -9.195  1    139.33 ? 269 ILE D CD1 1 -0.053 0.632  -0.023 
ATOM   11479 N  N   . GLY D 1 281 ? -4.99   64.676  -7.099  1    143.83 ? 270 GLY D N   1 -0.046 0.593  -0.018 
ATOM   11480 C  CA  . GLY D 1 281 ? -4.937  64.624  -5.646  1    142.48 ? 270 GLY D CA  1 -0.045 0.592  -0.014 
ATOM   11481 C  C   . GLY D 1 281 ? -4.915  63.225  -5.07   1    143.04 ? 270 GLY D C   1 -0.045 0.579  -0.013 
ATOM   11482 O  O   . GLY D 1 281 ? -5.167  62.231  -5.759  1    146.53 ? 270 GLY D O   1 -0.047 0.57   -0.014 
ATOM   11483 N  N   . LYS D 1 282 ? -4.561  63.176  -3.782  1    142.61 ? 271 LYS D N   1 -0.042 0.579  -0.009 
ATOM   11484 C  CA  . LYS D 1 282 ? -4.753  62.051  -2.864  1    142.1  ? 271 LYS D CA  1 -0.044 0.569  -0.007 
ATOM   11485 C  C   . LYS D 1 282 ? -4.848  60.673  -3.531  1    143.04 ? 271 LYS D C   1 -0.044 0.556  -0.009 
ATOM   11486 O  O   . LYS D 1 282 ? -5.704  59.857  -3.156  1    137.49 ? 271 LYS D O   1 -0.052 0.549  -0.008 
ATOM   11487 C  CB  . LYS D 1 282 ? -6.007  62.316  -2.019  1    135.42 ? 271 LYS D CB  1 -0.055 0.571  -0.005 
ATOM   11488 C  CG  . LYS D 1 282 ? -6.62   63.737  -2.169  1    138.87 ? 271 LYS D CG  1 -0.061 0.584  -0.005 
ATOM   11489 C  CD  . LYS D 1 282 ? -5.715  64.898  -1.646  1    149.12 ? 271 LYS D CD  1 -0.052 0.595  -0.004 
ATOM   11490 C  CE  . LYS D 1 282 ? -6.406  66.272  -1.806  1    145.79 ? 271 LYS D CE  1 -0.059 0.607  -0.005 
ATOM   11491 N  NZ  . LYS D 1 282 ? -5.444  67.43   -1.848  1    139.69 ? 271 LYS D NZ  1 -0.05  0.618  -0.005 
ATOM   11492 N  N   . ASN D 1 283 ? -3.965  60.417  -4.516  1    143.91 ? 272 ASN D N   1 -0.036 0.554  -0.011 
ATOM   11493 C  CA  . ASN D 1 283 ? -3.836  59.128  -5.217  1    139.14 ? 272 ASN D CA  1 -0.035 0.542  -0.013 
ATOM   11494 C  C   . ASN D 1 283 ? -5.062  58.813  -6.078  1    139.77 ? 272 ASN D C   1 -0.046 0.539  -0.015 
ATOM   11495 O  O   . ASN D 1 283 ? -5.497  57.664  -6.173  1    139.28 ? 272 ASN D O   1 -0.05  0.528  -0.015 
ATOM   11496 C  CB  . ASN D 1 283 ? -3.544  57.991  -4.234  1    142.73 ? 272 ASN D CB  1 -0.032 0.531  -0.011 
ATOM   11497 C  CG  . ASN D 1 283 ? -2.344  58.289  -3.351  1    146.26 ? 272 ASN D CG  1 -0.021 0.534  -0.008 
ATOM   11498 O  OD1 . ASN D 1 283 ? -1.672  59.307  -3.531  1    145.63 ? 272 ASN D OD1 1 -0.015 0.543  -0.009 
ATOM   11499 N  ND2 . ASN D 1 283 ? -2.078  57.412  -2.382  1    143.55 ? 272 ASN D ND2 1 -0.019 0.526  -0.006 
ATOM   11500 N  N   . ILE D 1 284 ? -5.629  59.845  -6.692  1    136.11 ? 273 ILE D N   1 -0.052 0.548  -0.017 
ATOM   11501 C  CA  . ILE D 1 284 ? -6.641  59.711  -7.728  1    131.79 ? 273 ILE D CA  1 -0.061 0.547  -0.019 
ATOM   11502 C  C   . ILE D 1 284 ? -6.031  60.257  -9      1    142.99 ? 273 ILE D C   1 -0.055 0.552  -0.022 
ATOM   11503 O  O   . ILE D 1 284 ? -5.089  61.056  -8.945  1    146.3  ? 273 ILE D O   1 -0.047 0.56   -0.022 
ATOM   11504 C  CB  . ILE D 1 284 ? -7.934  60.468  -7.383  1    133.38 ? 273 ILE D CB  1 -0.073 0.554  -0.018 
ATOM   11505 C  CG1 . ILE D 1 284 ? -7.656  61.96   -7.315  1    136.79 ? 273 ILE D CG1 1 -0.07  0.568  -0.018 
ATOM   11506 C  CG2 . ILE D 1 284 ? -8.489  59.996  -6.07   1    136.02 ? 273 ILE D CG2 1 -0.078 0.55   -0.015 
ATOM   11507 C  CD1 . ILE D 1 284 ? -8.082  62.636  -8.586  1    139.55 ? 273 ILE D CD1 1 -0.074 0.574  -0.021 
ATOM   11508 N  N   . HIS D 1 285 ? -6.544  59.811  -10.144 1    141.41 ? 274 HIS D N   1 -0.06  0.548  -0.025 
ATOM   11509 C  CA  . HIS D 1 285 ? -6.003  60.191  -11.439 1    129.58 ? 274 HIS D CA  1 -0.055 0.552  -0.029 
ATOM   11510 C  C   . HIS D 1 285 ? -7.165  60.548  -12.344 1    131.74 ? 274 HIS D C   1 -0.066 0.555  -0.031 
ATOM   11511 O  O   . HIS D 1 285 ? -8.163  59.818  -12.393 1    125.98 ? 274 HIS D O   1 -0.075 0.548  -0.031 
ATOM   11512 C  CB  . HIS D 1 285 ? -5.153  59.071  -12.063 1    130.64 ? 274 HIS D CB  1 -0.047 0.541  -0.03  
ATOM   11513 C  CG  . HIS D 1 285 ? -4.072  58.561  -11.159 1    139.62 ? 274 HIS D CG  1 -0.037 0.537  -0.028 
ATOM   11514 N  ND1 . HIS D 1 285 ? -3.788  57.219  -11.017 1    141.23 ? 274 HIS D ND1 1 -0.035 0.524  -0.028 
ATOM   11515 C  CD2 . HIS D 1 285 ? -3.22   59.212  -10.329 1    139.9  ? 274 HIS D CD2 1 -0.03  0.543  -0.026 
ATOM   11516 C  CE1 . HIS D 1 285 ? -2.812  57.065  -10.138 1    137.62 ? 274 HIS D CE1 1 -0.026 0.523  -0.025 
ATOM   11517 N  NE2 . HIS D 1 285 ? -2.45   58.259  -9.704  1    136.26 ? 274 HIS D NE2 1 -0.022 0.534  -0.024 
ATOM   11518 N  N   . VAL D 1 286 ? -7.045  61.697  -13.024 1    134.9  ? 275 VAL D N   1 -0.065 0.565  -0.033 
ATOM   11519 C  CA  . VAL D 1 286 ? -7.996  62.129  -14.039 1    123.88 ? 275 VAL D CA  1 -0.073 0.569  -0.035 
ATOM   11520 C  C   . VAL D 1 286 ? -7.47   61.685  -15.392 1    132.25 ? 275 VAL D C   1 -0.068 0.565  -0.038 
ATOM   11521 O  O   . VAL D 1 286 ? -6.259  61.604  -15.628 1    134.9  ? 275 VAL D O   1 -0.057 0.565  -0.039 
ATOM   11522 C  CB  . VAL D 1 286 ? -8.24   63.655  -14.001 1    119.71 ? 275 VAL D CB  1 -0.076 0.583  -0.035 
ATOM   11523 C  CG1 . VAL D 1 286 ? -7.045  64.429  -14.555 1    123.48 ? 275 VAL D CG1 1 -0.065 0.59   -0.036 
ATOM   11524 C  CG2 . VAL D 1 286 ? -9.517  64.006  -14.754 1    117.77 ? 275 VAL D CG2 1 -0.087 0.587  -0.037 
ATOM   11525 N  N   . TRP D 1 287 ? -8.396  61.371  -16.289 1    130.23 ? 276 TRP D N   1 -0.077 0.562  -0.041 
ATOM   11526 C  CA  . TRP D 1 287 ? -8.058  60.978  -17.647 1    128.43 ? 276 TRP D CA  1 -0.074 0.559  -0.044 
ATOM   11527 C  C   . TRP D 1 287 ? -8.912  61.799  -18.597 1    129.9  ? 276 TRP D C   1 -0.082 0.566  -0.046 
ATOM   11528 O  O   . TRP D 1 287 ? -10.144 61.791  -18.495 1    126.74 ? 276 TRP D O   1 -0.093 0.566  -0.046 
ATOM   11529 C  CB  . TRP D 1 287 ? -8.274  59.478  -17.846 1    128.94 ? 276 TRP D CB  1 -0.076 0.545  -0.045 
ATOM   11530 C  CG  . TRP D 1 287 ? -7.025  58.682  -17.649 1    131.21 ? 276 TRP D CG  1 -0.064 0.538  -0.044 
ATOM   11531 C  CD1 . TRP D 1 287 ? -5.938  58.667  -18.463 1    137.68 ? 276 TRP D CD1 1 -0.054 0.538  -0.046 
ATOM   11532 C  CD2 . TRP D 1 287 ? -6.732  57.782  -16.575 1    133.13 ? 276 TRP D CD2 1 -0.062 0.53   -0.041 
ATOM   11533 N  NE1 . TRP D 1 287 ? -4.981  57.817  -17.968 1    137.64 ? 276 TRP D NE1 1 -0.046 0.53   -0.045 
ATOM   11534 C  CE2 . TRP D 1 287 ? -5.443  57.258  -16.81  1    133.79 ? 276 TRP D CE2 1 -0.05  0.525  -0.042 
ATOM   11535 C  CE3 . TRP D 1 287 ? -7.428  57.374  -15.435 1    133.04 ? 276 TRP D CE3 1 -0.068 0.526  -0.039 
ATOM   11536 C  CZ2 . TRP D 1 287 ? -4.837  56.345  -15.955 1    135.31 ? 276 TRP D CZ2 1 -0.044 0.516  -0.04  
ATOM   11537 C  CZ3 . TRP D 1 287 ? -6.826  56.461  -14.581 1    135.68 ? 276 TRP D CZ3 1 -0.063 0.517  -0.036 
ATOM   11538 C  CH2 . TRP D 1 287 ? -5.541  55.956  -14.848 1    138.56 ? 276 TRP D CH2 1 -0.051 0.513  -0.037 
ATOM   11539 N  N   . HIS D 1 288 ? -8.261  62.528  -19.498 1    135.4  ? 277 HIS D N   1 -0.076 0.573  -0.049 
ATOM   11540 C  CA  . HIS D 1 288 ? -8.96   63.397  -20.431 1    134.41 ? 277 HIS D CA  1 -0.082 0.581  -0.051 
ATOM   11541 C  C   . HIS D 1 288 ? -9.062  62.73   -21.796 1    134.92 ? 277 HIS D C   1 -0.083 0.575  -0.054 
ATOM   11542 O  O   . HIS D 1 288 ? -8.196  61.942  -22.187 1    134.57 ? 277 HIS D O   1 -0.075 0.568  -0.055 
ATOM   11543 C  CB  . HIS D 1 288 ? -8.262  64.752  -20.565 1    130.12 ? 277 HIS D CB  1 -0.076 0.593  -0.051 
ATOM   11544 C  CG  . HIS D 1 288 ? -8.052  65.453  -19.26  1    139    ? 277 HIS D CG  1 -0.074 0.6    -0.048 
ATOM   11545 N  ND1 . HIS D 1 288 ? -9.085  66.016  -18.541 1    135.16 ? 277 HIS D ND1 1 -0.083 0.605  -0.046 
ATOM   11546 C  CD2 . HIS D 1 288 ? -6.925  65.681  -18.543 1    137.66 ? 277 HIS D CD2 1 -0.063 0.602  -0.046 
ATOM   11547 C  CE1 . HIS D 1 288 ? -8.604  66.567  -17.44  1    132.46 ? 277 HIS D CE1 1 -0.079 0.61   -0.044 
ATOM   11548 N  NE2 . HIS D 1 288 ? -7.296  66.376  -17.417 1    136.98 ? 277 HIS D NE2 1 -0.067 0.608  -0.043 
ATOM   11549 N  N   . HIS D 1 289 ? -10.151 63.046  -22.498 1    134.18 ? 278 HIS D N   1 -0.093 0.578  -0.056 
ATOM   11550 C  CA  . HIS D 1 289 ? -10.394 62.645  -23.876 1    130.27 ? 278 HIS D CA  1 -0.095 0.574  -0.06  
ATOM   11551 C  C   . HIS D 1 289 ? -11.562 63.47   -24.395 1    129.73 ? 278 HIS D C   1 -0.106 0.582  -0.061 
ATOM   11552 O  O   . HIS D 1 289 ? -12.716 63.207  -24.038 1    129.35 ? 278 HIS D O   1 -0.117 0.579  -0.06  
ATOM   11553 C  CB  . HIS D 1 289 ? -10.692 61.143  -23.985 1    130.69 ? 278 HIS D CB  1 -0.098 0.56   -0.06  
ATOM   11554 C  CG  . HIS D 1 289 ? -10.935 60.652  -25.386 1    138.53 ? 278 HIS D CG  1 -0.1   0.556  -0.063 
ATOM   11555 N  ND1 . HIS D 1 289 ? -11.438 61.45   -26.394 1    138.42 ? 278 HIS D ND1 1 -0.105 0.563  -0.066 
ATOM   11556 C  CD2 . HIS D 1 289 ? -10.748 59.429  -25.941 1    138.05 ? 278 HIS D CD2 1 -0.098 0.545  -0.065 
ATOM   11557 C  CE1 . HIS D 1 289 ? -11.551 60.744  -27.505 1    135.5  ? 278 HIS D CE1 1 -0.106 0.557  -0.069 
ATOM   11558 N  NE2 . HIS D 1 289 ? -11.137 59.514  -27.259 1    136.41 ? 278 HIS D NE2 1 -0.102 0.545  -0.068 
ATOM   11559 N  N   . ASN D 1 290 ? -11.271 64.465  -25.228 1    129.21 ? 279 ASN D N   1 -0.103 0.591  -0.063 
ATOM   11560 C  CA  . ASN D 1 290 ? -12.299 65.289  -25.871 1    132.04 ? 279 ASN D CA  1 -0.113 0.598  -0.065 
ATOM   11561 C  C   . ASN D 1 290 ? -13.076 65.979  -24.754 1    130.07 ? 279 ASN D C   1 -0.12  0.605  -0.062 
ATOM   11562 O  O   . ASN D 1 290 ? -12.449 66.562  -23.852 1    135.05 ? 279 ASN D O   1 -0.114 0.61   -0.06  
ATOM   11563 C  CB  . ASN D 1 290 ? -13.139 64.432  -26.823 1    135.86 ? 279 ASN D CB  1 -0.12  0.59   -0.067 
ATOM   11564 C  CG  . ASN D 1 290 ? -12.607 64.434  -28.256 1    133.35 ? 279 ASN D CG  1 -0.116 0.59   -0.071 
ATOM   11565 O  OD1 . ASN D 1 290 ? -11.399 64.515  -28.485 1    133.48 ? 279 ASN D OD1 1 -0.104 0.591  -0.071 
ATOM   11566 N  ND2 . ASN D 1 290 ? -13.517 64.35   -29.226 1    130.46 ? 279 ASN D ND2 1 -0.124 0.59   -0.073 
ATOM   11567 N  N   . ASN D 1 291 ? -14.405 65.922  -24.753 1    127.01 ? 280 ASN D N   1 -0.132 0.604  -0.062 
ATOM   11568 C  CA  . ASN D 1 291 ? -15.209 66.592  -23.741 1    135.07 ? 280 ASN D CA  1 -0.139 0.61   -0.059 
ATOM   11569 C  C   . ASN D 1 291 ? -15.564 65.695  -22.559 1    130.66 ? 280 ASN D C   1 -0.143 0.602  -0.056 
ATOM   11570 O  O   . ASN D 1 291 ? -16.157 66.18   -21.587 1    126.77 ? 280 ASN D O   1 -0.148 0.606  -0.054 
ATOM   11571 C  CB  . ASN D 1 291 ? -16.467 67.146  -24.401 1    130.66 ? 280 ASN D CB  1 -0.151 0.615  -0.061 
ATOM   11572 C  CG  . ASN D 1 291 ? -16.155 67.853  -25.688 1    128.81 ? 280 ASN D CG  1 -0.148 0.622  -0.064 
ATOM   11573 O  OD1 . ASN D 1 291 ? -15.072 68.426  -25.843 1    126.41 ? 280 ASN D OD1 1 -0.138 0.627  -0.065 
ATOM   11574 N  ND2 . ASN D 1 291 ? -17.086 67.806  -26.632 1    129.19 ? 280 ASN D ND2 1 -0.157 0.621  -0.066 
ATOM   11575 N  N   . LEU D 1 292 ? -15.219 64.41   -22.625 1    130.42 ? 281 LEU D N   1 -0.139 0.59   -0.056 
ATOM   11576 C  CA  . LEU D 1 292 ? -15.307 63.521  -21.476 1    128.44 ? 281 LEU D CA  1 -0.14  0.582  -0.054 
ATOM   11577 C  C   . LEU D 1 292 ? -14.092 63.71   -20.575 1    129.06 ? 281 LEU D C   1 -0.129 0.584  -0.051 
ATOM   11578 O  O   . LEU D 1 292 ? -12.97  63.912  -21.053 1    125.75 ? 281 LEU D O   1 -0.119 0.586  -0.053 
ATOM   11579 C  CB  . LEU D 1 292 ? -15.399 62.059  -21.932 1    125.46 ? 281 LEU D CB  1 -0.141 0.569  -0.055 
ATOM   11580 C  CG  . LEU D 1 292 ? -14.897 60.948  -21     1    122.34 ? 281 LEU D CG  1 -0.137 0.559  -0.052 
ATOM   11581 C  CD1 . LEU D 1 292 ? -15.832 60.816  -19.818 1    124.91 ? 281 LEU D CD1 1 -0.145 0.557  -0.049 
ATOM   11582 C  CD2 . LEU D 1 292 ? -14.756 59.612  -21.714 1    122.11 ? 281 LEU D CD2 1 -0.135 0.546  -0.054 
ATOM   11583 N  N   . ASN D 1 293 ? -14.329 63.656  -19.264 1    128.77 ? 282 ASN D N   1 -0.131 0.583  -0.048 
ATOM   11584 C  CA  . ASN D 1 293 ? -13.267 63.672  -18.268 1    125.89 ? 282 ASN D CA  1 -0.122 0.583  -0.046 
ATOM   11585 C  C   . ASN D 1 293 ? -13.552 62.565  -17.272 1    122.87 ? 282 ASN D C   1 -0.124 0.573  -0.043 
ATOM   11586 O  O   . ASN D 1 293 ? -14.597 62.577  -16.615 1    122.92 ? 282 ASN D O   1 -0.134 0.573  -0.041 
ATOM   11587 C  CB  . ASN D 1 293 ? -13.186 65.027  -17.569 1    126.43 ? 282 ASN D CB  1 -0.121 0.596  -0.044 
ATOM   11588 C  CG  . ASN D 1 293 ? -12.972 66.163  -18.542 1    129.98 ? 282 ASN D CG  1 -0.119 0.606  -0.046 
ATOM   11589 O  OD1 . ASN D 1 293 ? -11.835 66.466  -18.926 1    131.03 ? 282 ASN D OD1 1 -0.108 0.609  -0.047 
ATOM   11590 N  ND2 . ASN D 1 293 ? -14.068 66.796  -18.961 1    126.88 ? 282 ASN D ND2 1 -0.129 0.612  -0.047 
ATOM   11591 N  N   . TYR D 1 294 ? -12.634 61.61   -17.165 1    124.29 ? 283 TYR D N   1 -0.116 0.565  -0.043 
ATOM   11592 C  CA  . TYR D 1 294 ? -12.828 60.408  -16.36  1    123.35 ? 283 TYR D CA  1 -0.118 0.554  -0.041 
ATOM   11593 C  C   . TYR D 1 294 ? -11.894 60.452  -15.153 1    123.36 ? 283 TYR D C   1 -0.109 0.554  -0.038 
ATOM   11594 O  O   . TYR D 1 294 ? -10.669 60.347  -15.304 1    121.49 ? 283 TYR D O   1 -0.098 0.553  -0.038 
ATOM   11595 C  CB  . TYR D 1 294 ? -12.586 59.157  -17.204 1    121.51 ? 283 TYR D CB  1 -0.115 0.542  -0.043 
ATOM   11596 C  CG  . TYR D 1 294 ? -12.752 57.865  -16.447 1    120.38 ? 283 TYR D CG  1 -0.117 0.53   -0.041 
ATOM   11597 C  CD1 . TYR D 1 294 ? -14.003 57.28   -16.303 1    120.03 ? 283 TYR D CD1 1 -0.128 0.525  -0.041 
ATOM   11598 C  CD2 . TYR D 1 294 ? -11.657 57.232  -15.862 1    122.77 ? 283 TYR D CD2 1 -0.107 0.524  -0.04  
ATOM   11599 C  CE1 . TYR D 1 294 ? -14.163 56.093  -15.59  1    120.43 ? 283 TYR D CE1 1 -0.13  0.514  -0.039 
ATOM   11600 C  CE2 . TYR D 1 294 ? -11.805 56.047  -15.15  1    121.3  ? 283 TYR D CE2 1 -0.108 0.514  -0.038 
ATOM   11601 C  CZ  . TYR D 1 294 ? -13.059 55.481  -15.019 1    118.09 ? 283 TYR D CZ  1 -0.12  0.508  -0.037 
ATOM   11602 O  OH  . TYR D 1 294 ? -13.206 54.302  -14.323 1    112.8  ? 283 TYR D OH  1 -0.121 0.498  -0.036 
ATOM   11603 N  N   . TYR D 1 295 ? -12.482 60.595  -13.957 1    124.71 ? 284 TYR D N   1 -0.114 0.555  -0.035 
ATOM   11604 C  CA  . TYR D 1 295 ? -11.762 60.604  -12.685 1    120.02 ? 284 TYR D CA  1 -0.108 0.555  -0.032 
ATOM   11605 C  C   . TYR D 1 295 ? -11.802 59.211  -12.061 1    117.83 ? 284 TYR D C   1 -0.108 0.543  -0.03  
ATOM   11606 O  O   . TYR D 1 295 ? -12.887 58.674  -11.805 1    115.81 ? 284 TYR D O   1 -0.118 0.538  -0.029 
ATOM   11607 C  CB  . TYR D 1 295 ? -12.376 61.601  -11.706 1    115.12 ? 284 TYR D CB  1 -0.113 0.565  -0.029 
ATOM   11608 C  CG  . TYR D 1 295 ? -12.415 63.05   -12.135 1    116.42 ? 284 TYR D CG  1 -0.114 0.578  -0.03  
ATOM   11609 C  CD1 . TYR D 1 295 ? -13.513 63.561  -12.813 1    113.88 ? 284 TYR D CD1 1 -0.124 0.582  -0.032 
ATOM   11610 C  CD2 . TYR D 1 295 ? -11.378 63.925  -11.802 1    118.68 ? 284 TYR D CD2 1 -0.104 0.586  -0.029 
ATOM   11611 C  CE1 . TYR D 1 295 ? -13.567 64.891  -13.18  1    114.82 ? 284 TYR D CE1 1 -0.124 0.595  -0.033 
ATOM   11612 C  CE2 . TYR D 1 295 ? -11.423 65.264  -12.167 1    112.11 ? 284 TYR D CE2 1 -0.105 0.598  -0.03  
ATOM   11613 C  CZ  . TYR D 1 295 ? -12.522 65.737  -12.855 1    116.04 ? 284 TYR D CZ  1 -0.115 0.602  -0.032 
ATOM   11614 O  OH  . TYR D 1 295 ? -12.583 67.06   -13.228 1    124.63 ? 284 TYR D OH  1 -0.115 0.615  -0.033 
ATOM   11615 N  N   . ALA D 1 296 ? -10.634 58.648  -11.779 1    116.3  ? 285 ALA D N   1 -0.097 0.537  -0.029 
ATOM   11616 C  CA  . ALA D 1 296 ? -10.538 57.341  -11.14  1    121.43 ? 285 ALA D CA  1 -0.097 0.525  -0.028 
ATOM   11617 C  C   . ALA D 1 296 ? -10.294 57.534  -9.641  1    121.69 ? 285 ALA D C   1 -0.094 0.527  -0.024 
ATOM   11618 O  O   . ALA D 1 296 ? -9.255  58.069  -9.238  1    124.08 ? 285 ALA D O   1 -0.085 0.532  -0.023 
ATOM   11619 C  CB  . ALA D 1 296 ? -9.432  56.507  -11.782 1    125.31 ? 285 ALA D CB  1 -0.086 0.518  -0.029 
ATOM   11620 N  N   . VAL D 1 297 ? -11.249 57.097  -8.816  1    115.63 ? 286 VAL D N   1 -0.103 0.523  -0.022 
ATOM   11621 C  CA  . VAL D 1 297 ? -11.158 57.21   -7.36   1    120.39 ? 286 VAL D CA  1 -0.102 0.524  -0.018 
ATOM   11622 C  C   . VAL D 1 297 ? -10.964 55.803  -6.804  1    113.51 ? 286 VAL D C   1 -0.1   0.511  -0.017 
ATOM   11623 O  O   . VAL D 1 297 ? -11.924 55.034  -6.65   1    107.97 ? 286 VAL D O   1 -0.109 0.504  -0.017 
ATOM   11624 C  CB  . VAL D 1 297 ? -12.39  57.893  -6.751  1    117.59 ? 286 VAL D CB  1 -0.114 0.531  -0.017 
ATOM   11625 C  CG1 . VAL D 1 297 ? -12.243 57.961  -5.236  1    113.51 ? 286 VAL D CG1 1 -0.112 0.531  -0.013 
ATOM   11626 C  CG2 . VAL D 1 297 ? -12.596 59.294  -7.348  1    114.16 ? 286 VAL D CG2 1 -0.115 0.543  -0.018 
ATOM   11627 N  N   . ASP D 1 298 ? -9.722  55.461  -6.483  1    110.48 ? 287 ASP D N   1 -0.089 0.508  -0.016 
ATOM   11628 C  CA  . ASP D 1 298 ? -9.381  54.105  -6.081  1    116.91 ? 287 ASP D CA  1 -0.086 0.496  -0.015 
ATOM   11629 C  C   . ASP D 1 298 ? -9.416  53.976  -4.554  1    125.43 ? 287 ASP D C   1 -0.086 0.495  -0.011 
ATOM   11630 O  O   . ASP D 1 298 ? -8.652  54.646  -3.843  1    125.4  ? 287 ASP D O   1 -0.079 0.501  -0.01  
ATOM   11631 C  CB  . ASP D 1 298 ? -8.014  53.73   -6.651  1    121.54 ? 287 ASP D CB  1 -0.073 0.492  -0.017 
ATOM   11632 C  CG  . ASP D 1 298 ? -7.543  52.365  -6.191  1    125.68 ? 287 ASP D CG  1 -0.069 0.48   -0.015 
ATOM   11633 O  OD1 . ASP D 1 298 ? -7.124  52.246  -5.024  1    129.71 ? 287 ASP D OD1 1 -0.065 0.479  -0.013 
ATOM   11634 O  OD2 . ASP D 1 298 ? -7.601  51.41   -6.987  1    124.89 ? 287 ASP D OD2 1 -0.07  0.471  -0.017 
ATOM   11635 N  N   . LEU D 1 299 ? -10.295 53.1    -4.052  1    119.47 ? 288 LEU D N   1 -0.094 0.487  -0.01  
ATOM   11636 C  CA  . LEU D 1 299 ? -10.451 52.936  -2.611  1    114.84 ? 288 LEU D CA  1 -0.096 0.485  -0.007 
ATOM   11637 C  C   . LEU D 1 299 ? -9.2    52.354  -1.962  1    121.9  ? 288 LEU D C   1 -0.084 0.48   -0.005 
ATOM   11638 O  O   . LEU D 1 299 ? -8.893  52.695  -0.813  1    136.36 ? 288 LEU D O   1 -0.081 0.483  -0.002 
ATOM   11639 C  CB  . LEU D 1 299 ? -11.661 52.051  -2.293  1    113.21 ? 288 LEU D CB  1 -0.107 0.477  -0.006 
ATOM   11640 C  CG  . LEU D 1 299 ? -13.071 52.636  -2.34   1    110.69 ? 288 LEU D CG  1 -0.12  0.482  -0.006 
ATOM   11641 C  CD1 . LEU D 1 299 ? -13.425 52.865  -3.77   1    113.05 ? 288 LEU D CD1 1 -0.123 0.484  -0.009 
ATOM   11642 C  CD2 . LEU D 1 299 ? -14.088 51.712  -1.644  1    112.2  ? 288 LEU D CD2 1 -0.129 0.474  -0.004 
ATOM   11643 N  N   . SER D 1 300 ? -8.47   51.477  -2.654  1    120.7  ? 289 SER D N   1 -0.078 0.472  -0.007 
ATOM   11644 C  CA  . SER D 1 300 ? -7.242  50.942  -2.071  1    122.19 ? 289 SER D CA  1 -0.066 0.467  -0.005 
ATOM   11645 C  C   . SER D 1 300 ? -6.22   52.037  -1.807  1    123.03 ? 289 SER D C   1 -0.057 0.477  -0.005 
ATOM   11646 O  O   . SER D 1 300 ? -5.344  51.864  -0.95   1    123.61 ? 289 SER D O   1 -0.049 0.475  -0.002 
ATOM   11647 C  CB  . SER D 1 300 ? -6.63   49.855  -2.97   1    125.7  ? 289 SER D CB  1 -0.061 0.457  -0.007 
ATOM   11648 O  OG  . SER D 1 300 ? -6.403  50.302  -4.299  1    132.28 ? 289 SER D OG  1 -0.059 0.461  -0.011 
ATOM   11649 N  N   . LEU D 1 301 ? -6.339  53.174  -2.485  1    121.24 ? 290 LEU D N   1 -0.058 0.487  -0.006 
ATOM   11650 C  CA  . LEU D 1 301 ? -5.39   54.262  -2.329  1    127.89 ? 290 LEU D CA  1 -0.049 0.497  -0.006 
ATOM   11651 C  C   . LEU D 1 301 ? -5.983  55.5    -1.667  1    129.17 ? 290 LEU D C   1 -0.055 0.509  -0.004 
ATOM   11652 O  O   . LEU D 1 301 ? -5.241  56.451  -1.406  1    131.48 ? 290 LEU D O   1 -0.048 0.517  -0.004 
ATOM   11653 C  CB  . LEU D 1 301 ? -4.795  54.636  -3.693  1    132.77 ? 290 LEU D CB  1 -0.044 0.501  -0.009 
ATOM   11654 C  CG  . LEU D 1 301 ? -3.56   53.849  -4.142  1    132.11 ? 290 LEU D CG  1 -0.033 0.493  -0.01  
ATOM   11655 C  CD1 . LEU D 1 301 ? -3.93   52.452  -4.627  1    128.62 ? 290 LEU D CD1 1 -0.036 0.481  -0.012 
ATOM   11656 C  CD2 . LEU D 1 301 ? -2.812  54.62   -5.221  1    135.97 ? 290 LEU D CD2 1 -0.026 0.501  -0.013 
ATOM   11657 N  N   . THR D 1 302 ? -7.301  55.519  -1.378  1    130.35 ? 291 THR D N   1 -0.067 0.509  -0.003 
ATOM   11658 C  CA  . THR D 1 302 ? -7.988  56.693  -0.805  1    131.88 ? 291 THR D CA  1 -0.073 0.52   -0.002 
ATOM   11659 C  C   . THR D 1 302 ? -8.993  56.194  0.245   1    126.06 ? 291 THR D C   1 -0.082 0.515  0.001  
ATOM   11660 O  O   . THR D 1 302 ? -10.212 56.263  0.077   1    120.61 ? 291 THR D O   1 -0.094 0.516  0.0    
ATOM   11661 C  CB  . THR D 1 302 ? -8.661  57.534  -1.901  1    126.64 ? 291 THR D CB  1 -0.079 0.527  -0.005 
ATOM   11662 O  OG1 . THR D 1 302 ? -7.714  57.807  -2.941  1    123.5  ? 291 THR D OG1 1 -0.071 0.53   -0.007 
ATOM   11663 C  CG2 . THR D 1 302 ? -9.143  58.874  -1.352  1    128.8  ? 291 THR D CG2 1 -0.084 0.54   -0.003 
ATOM   11664 N  N   . SER D 1 303 ? -8.46   55.683  1.362   1    129.48 ? 292 SER D N   1 -0.078 0.51   0.003  
ATOM   11665 C  CA  . SER D 1 303 ? -9.239  55.044  2.43    1    135.29 ? 292 SER D CA  1 -0.085 0.504  0.006  
ATOM   11666 C  C   . SER D 1 303 ? -10.031 56.017  3.316   1    133.21 ? 292 SER D C   1 -0.092 0.513  0.008  
ATOM   11667 O  O   . SER D 1 303 ? -10.729 56.895  2.816   1    136.27 ? 292 SER D O   1 -0.098 0.521  0.007  
ATOM   11668 C  CB  . SER D 1 303 ? -8.302  54.203  3.299   1    135.5  ? 292 SER D CB  1 -0.076 0.497  0.008  
ATOM   11669 O  OG  . SER D 1 303 ? -7.45   55.022  4.098   1    137    ? 292 SER D OG  1 -0.068 0.504  0.01   
ATOM   11670 N  N   . ARG D 1 304 ? -9.977  55.862  4.639   1    133.01 ? 293 ARG D N   1 -0.091 0.512  0.012  
ATOM   11671 C  CA  . ARG D 1 304 ? -10.674 56.783  5.522   1    128.46 ? 293 ARG D CA  1 -0.098 0.52   0.014  
ATOM   11672 C  C   . ARG D 1 304 ? -9.63   57.396  6.423   1    133.87 ? 293 ARG D C   1 -0.088 0.526  0.016  
ATOM   11673 O  O   . ARG D 1 304 ? -8.66   56.733  6.794   1    131.42 ? 293 ARG D O   1 -0.079 0.52   0.017  
ATOM   11674 C  CB  . ARG D 1 304 ? -11.769 56.126  6.393   1    120.93 ? 293 ARG D CB  1 -0.108 0.514  0.016  
ATOM   11675 C  CG  . ARG D 1 304 ? -12.61  57.179  7.165   1    125.82 ? 293 ARG D CG  1 -0.116 0.524  0.018  
ATOM   11676 C  CD  . ARG D 1 304 ? -13.654 56.591  8.084   1    129.19 ? 293 ARG D CD  1 -0.125 0.519  0.02   
ATOM   11677 N  NE  . ARG D 1 304 ? -14.903 56.376  7.371   1    121.8  ? 293 ARG D NE  1 -0.137 0.517  0.018  
ATOM   11678 C  CZ  . ARG D 1 304 ? -15.213 55.242  6.763   1    119.07 ? 293 ARG D CZ  1 -0.139 0.506  0.017  
ATOM   11679 N  NH1 . ARG D 1 304 ? -14.364 54.229  6.724   1    122.79 ? 293 ARG D NH1 1 -0.132 0.497  0.017  
ATOM   11680 N  NH2 . ARG D 1 304 ? -16.408 55.116  6.194   1    115.12 ? 293 ARG D NH2 1 -0.15  0.505  0.015  
ATOM   11681 N  N   . LYS D 1 305 ? -9.858  58.669  6.764   1    139.09 ? 294 LYS D N   1 -0.09  0.538  0.017  
ATOM   11682 C  CA  . LYS D 1 305 ? -8.955  59.554  7.515   1    140.73 ? 294 LYS D CA  1 -0.082 0.546  0.019  
ATOM   11683 C  C   . LYS D 1 305 ? -9.528  59.888  8.902   1    136.76 ? 294 LYS D C   1 -0.087 0.549  0.022  
ATOM   11684 O  O   . LYS D 1 305 ? -10.146 60.943  9.074   1    136.59 ? 294 LYS D O   1 -0.093 0.558  0.023  
ATOM   11685 C  CB  . LYS D 1 305 ? -8.738  60.859  6.702   1    141.49 ? 294 LYS D CB  1 -0.08  0.558  0.017  
ATOM   11686 C  CG  . LYS D 1 305 ? -7.532  60.912  5.764   1    140.77 ? 294 LYS D CG  1 -0.069 0.558  0.014  
ATOM   11687 C  CD  . LYS D 1 305 ? -7.219  59.565  5.129   1    138.12 ? 294 LYS D CD  1 -0.066 0.546  0.013  
ATOM   11688 C  CE  . LYS D 1 305 ? -8.144  59.182  3.972   1    132.47 ? 294 LYS D CE  1 -0.075 0.542  0.01   
ATOM   11689 N  NZ  . LYS D 1 305 ? -7.819  57.789  3.564   1    131.27 ? 294 LYS D NZ  1 -0.072 0.53   0.009  
ATOM   11690 N  N   . SER D 1 306 ? -9.287  59.037  9.896   1    134.79 ? 295 SER D N   1 -0.085 0.541  0.025  
ATOM   11691 C  CA  . SER D 1 306 ? -9.83   59.226  11.259  1    141.25 ? 295 SER D CA  1 -0.09  0.543  0.028  
ATOM   11692 C  C   . SER D 1 306 ? -11.356 59.324  11.149  1    137.25 ? 295 SER D C   1 -0.104 0.544  0.028  
ATOM   11693 O  O   . SER D 1 306 ? -11.964 58.697  10.271  1    140.96 ? 295 SER D O   1 -0.11  0.538  0.026  
ATOM   11694 C  CB  . SER D 1 306 ? -9.173  60.422  11.955  1    140.86 ? 295 SER D CB  1 -0.084 0.554  0.03   
ATOM   11695 O  OG  . SER D 1 306 ? -9.726  61.648  11.497  1    139.41 ? 295 SER D OG  1 -0.089 0.565  0.029  
ATOM   11696 N  N   . VAL D 1 307 ? -11.985 60.112  12.024  1    131.58 ? 296 VAL D N   1 -0.11  0.551  0.03   
ATOM   11697 C  CA  . VAL D 1 307 ? -13.429 60.31   11.987  1    129.44 ? 296 VAL D CA  1 -0.123 0.553  0.03   
ATOM   11698 C  C   . VAL D 1 307 ? -13.775 61.307  10.88   1    127.15 ? 296 VAL D C   1 -0.126 0.562  0.027  
ATOM   11699 O  O   . VAL D 1 307 ? -12.977 62.189  10.529  1    124.85 ? 296 VAL D O   1 -0.119 0.57   0.026  
ATOM   11700 C  CB  . VAL D 1 307 ? -13.923 60.768  13.378  1    127.67 ? 296 VAL D CB  1 -0.128 0.557  0.033  
ATOM   11701 C  CG1 . VAL D 1 307 ? -13.514 62.196  13.638  1    123.58 ? 296 VAL D CG1 1 -0.124 0.57   0.034  
ATOM   11702 C  CG2 . VAL D 1 307 ? -15.431 60.579  13.538  1    120.12 ? 296 VAL D CG2 1 -0.141 0.555  0.034  
ATOM   11703 N  N   . GLY D 1 308 ? -14.961 61.146  10.292  1    121.35 ? 297 GLY D N   1 -0.137 0.56   0.026  
ATOM   11704 C  CA  . GLY D 1 308 ? -15.366 61.986  9.181   1    118.8  ? 297 GLY D CA  1 -0.141 0.568  0.023  
ATOM   11705 C  C   . GLY D 1 308 ? -15.814 61.194  7.968   1    121.86 ? 297 GLY D C   1 -0.145 0.561  0.02   
ATOM   11706 O  O   . GLY D 1 308 ? -15.473 60.012  7.832   1    124.54 ? 297 GLY D O   1 -0.142 0.55   0.02   
ATOM   11707 N  N   . VAL D 1 309 ? -16.576 61.836  7.076   1    121.91 ? 298 VAL D N   1 -0.152 0.567  0.018  
ATOM   11708 C  CA  . VAL D 1 309 ? -17.123 61.151  5.906   1    116.07 ? 298 VAL D CA  1 -0.157 0.56   0.015  
ATOM   11709 C  C   . VAL D 1 309 ? -16.006 60.788  4.94    1    112.72 ? 298 VAL D C   1 -0.147 0.557  0.012  
ATOM   11710 O  O   . VAL D 1 309 ? -15.113 61.6    4.661   1    112.99 ? 298 VAL D O   1 -0.138 0.565  0.012  
ATOM   11711 C  CB  . VAL D 1 309 ? -18.194 62.018  5.225   1    113.69 ? 298 VAL D CB  1 -0.167 0.568  0.013  
ATOM   11712 C  CG1 . VAL D 1 309 ? -18.263 61.72   3.763   1    111.26 ? 298 VAL D CG1 1 -0.167 0.566  0.009  
ATOM   11713 C  CG2 . VAL D 1 309 ? -19.549 61.744  5.853   1    118.97 ? 298 VAL D CG2 1 -0.179 0.566  0.015  
ATOM   11714 N  N   . HIS D 1 310 ? -16.069 59.559  4.425   1    115.62 ? 299 HIS D N   1 -0.147 0.546  0.011  
ATOM   11715 C  CA  . HIS D 1 310 ? -15.032 58.979  3.579   1    113.43 ? 299 HIS D CA  1 -0.138 0.54   0.009  
ATOM   11716 C  C   . HIS D 1 310 ? -14.631 59.94   2.459   1    112.29 ? 299 HIS D C   1 -0.134 0.549  0.006  
ATOM   11717 O  O   . HIS D 1 310 ? -15.506 60.442  1.734   1    114.51 ? 299 HIS D O   1 -0.142 0.554  0.004  
ATOM   11718 C  CB  . HIS D 1 310 ? -15.56  57.671  2.992   1    112.62 ? 299 HIS D CB  1 -0.143 0.529  0.007  
ATOM   11719 C  CG  . HIS D 1 310 ? -14.499 56.719  2.537   1    114.6  ? 299 HIS D CG  1 -0.133 0.52   0.006  
ATOM   11720 N  ND1 . HIS D 1 310 ? -13.741 56.93   1.405   1    119.22 ? 299 HIS D ND1 1 -0.126 0.522  0.004  
ATOM   11721 C  CD2 . HIS D 1 310 ? -14.11  55.521  3.034   1    112.25 ? 299 HIS D CD2 1 -0.129 0.509  0.008  
ATOM   11722 C  CE1 . HIS D 1 310 ? -12.916 55.913  1.236   1    121.14 ? 299 HIS D CE1 1 -0.118 0.512  0.003  
ATOM   11723 N  NE2 . HIS D 1 310 ? -13.112 55.047  2.216   1    115.72 ? 299 HIS D NE2 1 -0.12  0.504  0.006  
ATOM   11724 N  N   . PRO D 1 311 ? -13.332 60.213  2.277   1    112.63 ? 300 PRO D N   1 -0.122 0.552  0.006  
ATOM   11725 C  CA  . PRO D 1 311 ? -12.918 61.243  1.303   1    115.6  ? 300 PRO D CA  1 -0.118 0.561  0.003  
ATOM   11726 C  C   . PRO D 1 311 ? -13.15  60.856  -0.15   1    113.65 ? 300 PRO D C   1 -0.121 0.558  -0.0   
ATOM   11727 O  O   . PRO D 1 311 ? -13.074 61.738  -1.015  1    110.82 ? 300 PRO D O   1 -0.12  0.566  -0.003 
ATOM   11728 C  CB  . PRO D 1 311 ? -11.422 61.424  1.595   1    114.17 ? 300 PRO D CB  1 -0.105 0.563  0.004  
ATOM   11729 C  CG  . PRO D 1 311 ? -10.996 60.115  2.185   1    114.25 ? 300 PRO D CG  1 -0.101 0.551  0.005  
ATOM   11730 C  CD  . PRO D 1 311 ? -12.182 59.601  2.965   1    113.7  ? 300 PRO D CD  1 -0.112 0.546  0.007  
ATOM   11731 N  N   . ALA D 1 312 ? -13.392 59.573  -0.439  1    112.76 ? 301 ALA D N   1 -0.123 0.546  -0.001 
ATOM   11732 C  CA  . ALA D 1 312 ? -13.915 59.177  -1.741  1    109.5  ? 301 ALA D CA  1 -0.128 0.542  -0.004 
ATOM   11733 C  C   . ALA D 1 312 ? -15.215 59.902  -2.052  1    113.07 ? 301 ALA D C   1 -0.139 0.549  -0.005 
ATOM   11734 O  O   . ALA D 1 312 ? -15.429 60.349  -3.186  1    113.77 ? 301 ALA D O   1 -0.141 0.553  -0.008 
ATOM   11735 C  CB  . ALA D 1 312 ? -14.137 57.666  -1.772  1    110.69 ? 301 ALA D CB  1 -0.13  0.528  -0.004 
ATOM   11736 N  N   . LEU D 1 313 ? -16.091 60.031  -1.051  1    114.09 ? 302 LEU D N   1 -0.147 0.55   -0.003 
ATOM   11737 C  CA  . LEU D 1 313 ? -17.382 60.696  -1.195  1    114.43 ? 302 LEU D CA  1 -0.159 0.556  -0.003 
ATOM   11738 C  C   . LEU D 1 313 ? -17.296 62.209  -1.013  1    117.95 ? 302 LEU D C   1 -0.159 0.57   -0.003 
ATOM   11739 O  O   . LEU D 1 313 ? -18.186 62.929  -1.489  1    115.87 ? 302 LEU D O   1 -0.167 0.577  -0.004 
ATOM   11740 C  CB  . LEU D 1 313 ? -18.393 60.122  -0.19   1    111.01 ? 302 LEU D CB  1 -0.169 0.551  -0.0   
ATOM   11741 C  CG  . LEU D 1 313 ? -18.399 58.6    -0.031  1    110.04 ? 302 LEU D CG  1 -0.169 0.537  -0.0   
ATOM   11742 C  CD1 . LEU D 1 313 ? -19.61  58.129  0.737   1    105    ? 302 LEU D CD1 1 -0.18  0.533  0.002  
ATOM   11743 C  CD2 . LEU D 1 313 ? -18.357 57.925  -1.399  1    116.74 ? 302 LEU D CD2 1 -0.168 0.531  -0.003 
ATOM   11744 N  N   . LEU D 1 314 ? -16.26  62.704  -0.327  1    118.63 ? 303 LEU D N   1 -0.149 0.575  -0.001 
ATOM   11745 C  CA  . LEU D 1 314 ? -16.039 64.147  -0.248  1    121.11 ? 303 LEU D CA  1 -0.147 0.588  -0.001 
ATOM   11746 C  C   . LEU D 1 314 ? -15.614 64.716  -1.6    1    119.88 ? 303 LEU D C   1 -0.143 0.593  -0.004 
ATOM   11747 O  O   . LEU D 1 314 ? -16.205 65.691  -2.08   1    121.58 ? 303 LEU D O   1 -0.149 0.602  -0.005 
ATOM   11748 C  CB  . LEU D 1 314 ? -15     64.454  0.835   1    122.58 ? 303 LEU D CB  1 -0.137 0.591  0.002  
ATOM   11749 C  CG  . LEU D 1 314 ? -15.471 64.185  2.264   1    115.95 ? 303 LEU D CG  1 -0.142 0.588  0.006  
ATOM   11750 C  CD1 . LEU D 1 314 ? -14.482 64.738  3.289   1    117.76 ? 303 LEU D CD1 1 -0.133 0.593  0.008  
ATOM   11751 C  CD2 . LEU D 1 314 ? -16.855 64.779  2.467   1    117.32 ? 303 LEU D CD2 1 -0.154 0.594  0.006  
ATOM   11752 N  N   . PHE D 1 315 ? -14.569 64.135  -2.207  1    120.97 ? 304 PHE D N   1 -0.134 0.588  -0.006 
ATOM   11753 C  CA  . PHE D 1 315 ? -14.221 64.331  -3.616  1    116.98 ? 304 PHE D CA  1 -0.13  0.59   -0.009 
ATOM   11754 C  C   . PHE D 1 315 ? -15.477 64.359  -4.481  1    114.31 ? 304 PHE D C   1 -0.142 0.59   -0.011 
ATOM   11755 O  O   . PHE D 1 315 ? -15.747 65.344  -5.181  1    113.47 ? 304 PHE D O   1 -0.144 0.599  -0.013 
ATOM   11756 C  CB  . PHE D 1 315 ? -13.261 63.204  -4.03   1    113.53 ? 304 PHE D CB  1 -0.122 0.579  -0.01  
ATOM   11757 C  CG  . PHE D 1 315 ? -12.637 63.325  -5.416  1    124.95 ? 304 PHE D CG  1 -0.116 0.58   -0.014 
ATOM   11758 C  CD1 . PHE D 1 315 ? -13.195 64.089  -6.457  1    129.8  ? 304 PHE D CD1 1 -0.121 0.587  -0.016 
ATOM   11759 C  CD2 . PHE D 1 315 ? -11.486 62.601  -5.688  1    130.17 ? 304 PHE D CD2 1 -0.105 0.574  -0.014 
ATOM   11760 C  CE1 . PHE D 1 315 ? -12.608 64.137  -7.735  1    122.85 ? 304 PHE D CE1 1 -0.116 0.588  -0.019 
ATOM   11761 C  CE2 . PHE D 1 315 ? -10.907 62.649  -6.949  1    136.69 ? 304 PHE D CE2 1 -0.1   0.574  -0.017 
ATOM   11762 C  CZ  . PHE D 1 315 ? -11.465 63.424  -7.976  1    125.7  ? 304 PHE D CZ  1 -0.105 0.581  -0.02  
ATOM   11763 N  N   . ALA D 1 316 ? -16.271 63.289  -4.418  1    110.2  ? 305 ALA D N   1 -0.149 0.58   -0.011 
ATOM   11764 C  CA  . ALA D 1 316 ? -17.468 63.209  -5.249  1    109.92 ? 305 ALA D CA  1 -0.16  0.579  -0.013 
ATOM   11765 C  C   . ALA D 1 316 ? -18.363 64.42   -5.034  1    108.03 ? 305 ALA D C   1 -0.168 0.59   -0.013 
ATOM   11766 O  O   . ALA D 1 316 ? -18.81  65.059  -5.988  1    115.83 ? 305 ALA D O   1 -0.172 0.596  -0.015 
ATOM   11767 C  CB  . ALA D 1 316 ? -18.231 61.915  -4.964  1    104.3  ? 305 ALA D CB  1 -0.167 0.567  -0.012 
ATOM   11768 N  N   . LEU D 1 317 ? -18.616 64.767  -3.781  1    118.09 ? 306 LEU D N   1 -0.171 0.594  -0.009 
ATOM   11769 C  CA  . LEU D 1 317 ? -19.444 65.936  -3.521  1    118.13 ? 306 LEU D CA  1 -0.178 0.604  -0.009 
ATOM   11770 C  C   . LEU D 1 317 ? -18.739 67.215  -3.949  1    119.02 ? 306 LEU D C   1 -0.172 0.616  -0.01  
ATOM   11771 O  O   . LEU D 1 317 ? -19.371 68.104  -4.529  1    117.71 ? 306 LEU D O   1 -0.178 0.624  -0.011 
ATOM   11772 C  CB  . LEU D 1 317 ? -19.828 65.978  -2.05   1    111.95 ? 306 LEU D CB  1 -0.182 0.605  -0.005 
ATOM   11773 C  CG  . LEU D 1 317 ? -20.846 64.885  -1.752  1    111.93 ? 306 LEU D CG  1 -0.191 0.595  -0.004 
ATOM   11774 C  CD1 . LEU D 1 317 ? -20.972 64.641  -0.241  1    115.23 ? 306 LEU D CD1 1 -0.192 0.592  -0.001 
ATOM   11775 C  CD2 . LEU D 1 317 ? -22.18  65.271  -2.378  1    104.92 ? 306 LEU D CD2 1 -0.203 0.598  -0.006 
ATOM   11776 N  N   . GLU D 1 318 ? -17.429 67.313  -3.696  1    119    ? 307 GLU D N   1 -0.16  0.617  -0.009 
ATOM   11777 C  CA  . GLU D 1 318 ? -16.666 68.479  -4.132  1    117.74 ? 307 GLU D CA  1 -0.153 0.628  -0.01  
ATOM   11778 C  C   . GLU D 1 318 ? -16.797 68.693  -5.637  1    125.36 ? 307 GLU D C   1 -0.154 0.63   -0.014 
ATOM   11779 O  O   . GLU D 1 318 ? -17.135 69.798  -6.086  1    125.44 ? 307 GLU D O   1 -0.157 0.64   -0.015 
ATOM   11780 C  CB  . GLU D 1 318 ? -15.2   68.329  -3.727  1    115.47 ? 307 GLU D CB  1 -0.139 0.626  -0.009 
ATOM   11781 C  CG  . GLU D 1 318 ? -14.985 68.535  -2.24   1    122.47 ? 307 GLU D CG  1 -0.137 0.628  -0.006 
ATOM   11782 C  CD  . GLU D 1 318 ? -13.591 68.143  -1.756  1    133.67 ? 307 GLU D CD  1 -0.125 0.624  -0.004 
ATOM   11783 O  OE1 . GLU D 1 318 ? -12.92  67.339  -2.446  1    133.23 ? 307 GLU D OE1 1 -0.118 0.617  -0.006 
ATOM   11784 O  OE2 . GLU D 1 318 ? -13.172 68.644  -0.679  1    135.35 ? 307 GLU D OE2 1 -0.121 0.629  -0.002 
ATOM   11785 N  N   . GLN D 1 319 ? -16.541 67.652  -6.439  1    123.51 ? 308 GLN D N   1 -0.152 0.62   -0.016 
ATOM   11786 C  CA  . GLN D 1 319 ? -16.692 67.781  -7.886  1    120.91 ? 308 GLN D CA  1 -0.153 0.621  -0.02  
ATOM   11787 C  C   . GLN D 1 319 ? -18.089 68.25   -8.244  1    118.26 ? 308 GLN D C   1 -0.166 0.625  -0.021 
ATOM   11788 O  O   . GLN D 1 319 ? -18.267 69.253  -8.938  1    124.35 ? 308 GLN D O   1 -0.167 0.635  -0.022 
ATOM   11789 C  CB  . GLN D 1 319 ? -16.411 66.455  -8.598  1    123.23 ? 308 GLN D CB  1 -0.15  0.609  -0.021 
ATOM   11790 C  CG  . GLN D 1 319 ? -14.965 66.061  -8.759  1    126.91 ? 308 GLN D CG  1 -0.137 0.605  -0.022 
ATOM   11791 C  CD  . GLN D 1 319 ? -14.017 67.232  -8.787  1    129.26 ? 308 GLN D CD  1 -0.128 0.616  -0.022 
ATOM   11792 O  OE1 . GLN D 1 319 ? -14.074 68.092  -9.686  1    127.88 ? 308 GLN D OE1 1 -0.129 0.624  -0.024 
ATOM   11793 N  NE2 . GLN D 1 319 ? -13.117 67.276  -7.8    1    125.95 ? 308 GLN D NE2 1 -0.12  0.617  -0.019 
ATOM   11794 N  N   . LEU D 1 320 ? -19.099 67.515  -7.774  1    113.83 ? 309 LEU D N   1 -0.175 0.619  -0.019 
ATOM   11795 C  CA  . LEU D 1 320 ? -20.484 67.87   -8.064  1    113.16 ? 309 LEU D CA  1 -0.188 0.622  -0.02  
ATOM   11796 C  C   . LEU D 1 320 ? -20.806 69.272  -7.563  1    122.9  ? 309 LEU D C   1 -0.191 0.635  -0.019 
ATOM   11797 O  O   . LEU D 1 320 ? -21.392 70.08   -8.295  1    117.31 ? 309 LEU D O   1 -0.196 0.642  -0.021 
ATOM   11798 C  CB  . LEU D 1 320 ? -21.418 66.838  -7.439  1    112.25 ? 309 LEU D CB  1 -0.196 0.613  -0.019 
ATOM   11799 C  CG  . LEU D 1 320 ? -22.893 67.142  -7.651  1    113.82 ? 309 LEU D CG  1 -0.21  0.615  -0.019 
ATOM   11800 C  CD1 . LEU D 1 320 ? -23.193 67.203  -9.155  1    109.76 ? 309 LEU D CD1 1 -0.213 0.616  -0.023 
ATOM   11801 C  CD2 . LEU D 1 320 ? -23.752 66.102  -6.912  1    100.32 ? 309 LEU D CD2 1 -0.218 0.606  -0.017 
ATOM   11802 N  N   . LYS D 1 321 ? -20.424 69.575  -6.306  1    128.93 ? 310 LYS D N   1 -0.187 0.638  -0.016 
ATOM   11803 C  CA  . LYS D 1 321 ? -20.536 70.934  -5.767  1    124.36 ? 310 LYS D CA  1 -0.188 0.65   -0.014 
ATOM   11804 C  C   . LYS D 1 321 ? -19.935 71.935  -6.743  1    132.41 ? 310 LYS D C   1 -0.183 0.659  -0.017 
ATOM   11805 O  O   . LYS D 1 321 ? -20.537 72.981  -7.021  1    136.81 ? 310 LYS D O   1 -0.188 0.669  -0.018 
ATOM   11806 C  CB  . LYS D 1 321 ? -19.848 71.035  -4.398  1    120.95 ? 310 LYS D CB  1 -0.182 0.651  -0.011 
ATOM   11807 C  CG  . LYS D 1 321 ? -19.917 72.392  -3.647  1    125.68 ? 310 LYS D CG  1 -0.183 0.663  -0.009 
ATOM   11808 C  CD  . LYS D 1 321 ? -19.686 72.157  -2.119  1    137.15 ? 310 LYS D CD  1 -0.18  0.661  -0.005 
ATOM   11809 C  CE  . LYS D 1 321 ? -19.07  73.338  -1.354  1    133.03 ? 310 LYS D CE  1 -0.175 0.672  -0.003 
ATOM   11810 N  NZ  . LYS D 1 321 ? -20.031 74.443  -1.131  1    131.13 ? 310 LYS D NZ  1 -0.184 0.682  -0.003 
ATOM   11811 N  N   . GLU D 1 322 ? -18.763 71.616  -7.299  1    127.83 ? 311 GLU D N   1 -0.172 0.656  -0.018 
ATOM   11812 C  CA  . GLU D 1 322 ? -18.2   72.426  -8.366  1    129.36 ? 311 GLU D CA  1 -0.167 0.664  -0.021 
ATOM   11813 C  C   . GLU D 1 322 ? -19.153 72.427  -9.56   1    132.29 ? 311 GLU D C   1 -0.176 0.664  -0.024 
ATOM   11814 O  O   . GLU D 1 322 ? -19.934 73.376  -9.712  1    133.57 ? 311 GLU D O   1 -0.183 0.672  -0.024 
ATOM   11815 C  CB  . GLU D 1 322 ? -16.802 71.921  -8.751  1    129.08 ? 311 GLU D CB  1 -0.154 0.659  -0.022 
ATOM   11816 C  CG  . GLU D 1 322 ? -16.15  72.613  -9.917  1    131.69 ? 311 GLU D CG  1 -0.148 0.665  -0.025 
ATOM   11817 C  CD  . GLU D 1 322 ? -16.332 74.109  -9.877  1    144.44 ? 311 GLU D CD  1 -0.15  0.679  -0.025 
ATOM   11818 O  OE1 . GLU D 1 322 ? -17.422 74.54   -10.315 1    144.91 ? 311 GLU D OE1 1 -0.16  0.683  -0.026 
ATOM   11819 O  OE2 . GLU D 1 322 ? -15.401 74.839  -9.439  1    144.15 ? 311 GLU D OE2 1 -0.141 0.686  -0.024 
ATOM   11820 N  N   . SER D 1 323 ? -19.135 71.361  -10.373 1    129.65 ? 312 SER D N   1 -0.175 0.654  -0.026 
ATOM   11821 C  CA  . SER D 1 323 ? -19.813 71.297  -11.673 1    128.23 ? 312 SER D CA  1 -0.182 0.653  -0.029 
ATOM   11822 C  C   . SER D 1 323 ? -21.157 72.017  -11.737 1    129.93 ? 312 SER D C   1 -0.194 0.66   -0.029 
ATOM   11823 O  O   . SER D 1 323 ? -21.624 72.349  -12.831 1    131.74 ? 312 SER D O   1 -0.198 0.663  -0.032 
ATOM   11824 C  CB  . SER D 1 323 ? -20.023 69.842  -12.107 1    123.01 ? 312 SER D CB  1 -0.183 0.64   -0.03  
ATOM   11825 O  OG  . SER D 1 323 ? -19.305 69.563  -13.299 1    126.2  ? 312 SER D OG  1 -0.177 0.637  -0.033 
ATOM   11826 N  N   . ILE D 1 324 ? -21.785 72.278  -10.586 1    131.52 ? 313 ILE D N   1 -0.2   0.662  -0.026 
ATOM   11827 C  CA  . ILE D 1 324 ? -23.096 72.916  -10.61  1    131.79 ? 313 ILE D CA  1 -0.212 0.668  -0.026 
ATOM   11828 C  C   . ILE D 1 324 ? -22.977 74.433  -10.754 1    134.61 ? 313 ILE D C   1 -0.211 0.682  -0.027 
ATOM   11829 O  O   . ILE D 1 324 ? -23.758 75.053  -11.49  1    139.31 ? 313 ILE D O   1 -0.218 0.688  -0.029 
ATOM   11830 C  CB  . ILE D 1 324 ? -23.915 72.507  -9.376  1    120.66 ? 313 ILE D CB  1 -0.219 0.664  -0.023 
ATOM   11831 C  CG1 . ILE D 1 324 ? -24.196 71.009  -9.444  1    119.71 ? 313 ILE D CG1 1 -0.222 0.651  -0.024 
ATOM   11832 C  CG2 . ILE D 1 324 ? -25.238 73.267  -9.334  1    113.34 ? 313 ILE D CG2 1 -0.231 0.671  -0.023 
ATOM   11833 C  CD1 . ILE D 1 324 ? -24.614 70.407  -8.13   1    128.95 ? 313 ILE D CD1 1 -0.226 0.645  -0.02  
ATOM   11834 N  N   . ARG D 1 325 ? -22.001 75.064  -10.092 1    129.51 ? 314 ARG D N   1 -0.202 0.688  -0.025 
ATOM   11835 C  CA  . ARG D 1 325 ? -21.857 76.505  -10.286 1    133.1  ? 314 ARG D CA  1 -0.2   0.701  -0.026 
ATOM   11836 C  C   . ARG D 1 325 ? -21.37  76.827  -11.693 1    139.39 ? 314 ARG D C   1 -0.196 0.704  -0.029 
ATOM   11837 O  O   . ARG D 1 325 ? -21.639 77.922  -12.204 1    140.81 ? 314 ARG D O   1 -0.198 0.714  -0.03  
ATOM   11838 C  CB  . ARG D 1 325 ? -20.93  77.116  -9.231  1    138.92 ? 314 ARG D CB  1 -0.192 0.707  -0.023 
ATOM   11839 C  CG  . ARG D 1 325 ? -19.502 76.613  -9.221  1    140.15 ? 314 ARG D CG  1 -0.179 0.702  -0.023 
ATOM   11840 C  CD  . ARG D 1 325 ? -18.648 77.227  -10.328 1    144.14 ? 314 ARG D CD  1 -0.171 0.708  -0.026 
ATOM   11841 N  NE  . ARG D 1 325 ? -18.307 78.631  -10.143 1    148.28 ? 314 ARG D NE  1 -0.168 0.721  -0.025 
ATOM   11842 C  CZ  . ARG D 1 325 ? -17.271 79.06   -9.437  1    150.77 ? 314 ARG D CZ  1 -0.158 0.725  -0.024 
ATOM   11843 N  NH1 . ARG D 1 325 ? -16.52  78.227  -8.733  1    151.9  ? 314 ARG D NH1 1 -0.151 0.717  -0.022 
ATOM   11844 N  NH2 . ARG D 1 325 ? -16.98  80.359  -9.436  1    153.75 ? 314 ARG D NH2 1 -0.156 0.736  -0.024 
ATOM   11845 N  N   . GLU D 1 326 ? -20.64  75.899  -12.319 1    140.64 ? 315 GLU D N   1 -0.189 0.696  -0.031 
ATOM   11846 C  CA  . GLU D 1 326 ? -20.287 76.053  -13.726 1    135.44 ? 315 GLU D CA  1 -0.186 0.697  -0.034 
ATOM   11847 C  C   . GLU D 1 326 ? -21.533 76.288  -14.566 1    133.62 ? 315 GLU D C   1 -0.197 0.699  -0.036 
ATOM   11848 O  O   . GLU D 1 326 ? -21.686 77.342  -15.194 1    136.04 ? 315 GLU D O   1 -0.199 0.709  -0.038 
ATOM   11849 C  CB  . GLU D 1 326 ? -19.536 74.815  -14.223 1    133.06 ? 315 GLU D CB  1 -0.179 0.686  -0.036 
ATOM   11850 C  CG  . GLU D 1 326 ? -18.238 74.512  -13.488 1    141.56 ? 315 GLU D CG  1 -0.167 0.683  -0.034 
ATOM   11851 C  CD  . GLU D 1 326 ? -17.086 75.416  -13.901 1    149.41 ? 315 GLU D CD  1 -0.157 0.691  -0.035 
ATOM   11852 O  OE1 . GLU D 1 326 ? -17.318 76.625  -14.132 1    147.04 ? 315 GLU D OE1 1 -0.159 0.702  -0.035 
ATOM   11853 O  OE2 . GLU D 1 326 ? -15.943 74.909  -14     1    152.48 ? 315 GLU D OE2 1 -0.146 0.686  -0.035 
ATOM   11854 N  N   . ALA D 1 327 ? -22.456 75.324  -14.556 1    131.15 ? 316 ALA D N   1 -0.206 0.69   -0.036 
ATOM   11855 C  CA  . ALA D 1 327 ? -23.615 75.399  -15.438 1    136.08 ? 316 ALA D CA  1 -0.216 0.691  -0.039 
ATOM   11856 C  C   . ALA D 1 327 ? -24.592 76.494  -15.024 1    139.84 ? 316 ALA D C   1 -0.225 0.701  -0.038 
ATOM   11857 O  O   . ALA D 1 327 ? -25.342 76.998  -15.874 1    136.24 ? 316 ALA D O   1 -0.232 0.706  -0.04  
ATOM   11858 C  CB  . ALA D 1 327 ? -24.325 74.048  -15.485 1    136.09 ? 316 ALA D CB  1 -0.223 0.679  -0.039 
ATOM   11859 N  N   . LYS D 1 328 ? -24.612 76.868  -13.734 1    138.84 ? 317 LYS D N   1 -0.226 0.704  -0.034 
ATOM   11860 C  CA  . LYS D 1 328 ? -25.508 77.937  -13.287 1    137.39 ? 317 LYS D CA  1 -0.234 0.714  -0.033 
ATOM   11861 C  C   . LYS D 1 328 ? -25.058 79.289  -13.839 1    134.88 ? 317 LYS D C   1 -0.23  0.727  -0.035 
ATOM   11862 O  O   . LYS D 1 328 ? -25.889 80.138  -14.189 1    128.79 ? 317 LYS D O   1 -0.237 0.734  -0.035 
ATOM   11863 C  CB  . LYS D 1 328 ? -25.576 77.96   -11.755 1    133.7  ? 317 LYS D CB  1 -0.234 0.714  -0.029 
ATOM   11864 C  CG  . LYS D 1 328 ? -26.909 78.431  -11.147 1    134.44 ? 317 LYS D CG  1 -0.247 0.719  -0.028 
ATOM   11865 C  CD  . LYS D 1 328 ? -26.787 78.611  -9.618  1    136.34 ? 317 LYS D CD  1 -0.245 0.72   -0.024 
ATOM   11866 C  CE  . LYS D 1 328 ? -28.139 78.788  -8.913  1    129.66 ? 317 LYS D CE  1 -0.258 0.722  -0.022 
ATOM   11867 N  NZ  . LYS D 1 328 ? -28.827 80.082  -9.232  1    130.3  ? 317 LYS D NZ  1 -0.264 0.734  -0.023 
ATOM   11868 N  N   . ALA D 1 329 ? -23.742 79.497  -13.942 1    132.2  ? 318 ALA D N   1 -0.218 0.729  -0.035 
ATOM   11869 C  CA  . ALA D 1 329 ? -23.197 80.706  -14.539 1    134.57 ? 318 ALA D CA  1 -0.213 0.74   -0.036 
ATOM   11870 C  C   . ALA D 1 329 ? -23.074 80.627  -16.057 1    138.52 ? 318 ALA D C   1 -0.211 0.739  -0.04  
ATOM   11871 O  O   . ALA D 1 329 ? -23.079 81.673  -16.715 1    141.53 ? 318 ALA D O   1 -0.211 0.748  -0.042 
ATOM   11872 C  CB  . ALA D 1 329 ? -21.824 81.018  -13.936 1    134.82 ? 318 ALA D CB  1 -0.2   0.742  -0.035 
ATOM   11873 N  N   . LYS D 1 330 ? -22.96  79.432  -16.634 1    137.52 ? 319 LYS D N   1 -0.21  0.728  -0.042 
ATOM   11874 C  CA  . LYS D 1 330 ? -22.893 79.297  -18.086 1    137.26 ? 319 LYS D CA  1 -0.21  0.727  -0.045 
ATOM   11875 C  C   . LYS D 1 330 ? -24.257 79.104  -18.732 1    139.02 ? 319 LYS D C   1 -0.222 0.725  -0.047 
ATOM   11876 O  O   . LYS D 1 330 ? -24.317 78.878  -19.945 1    141.99 ? 319 LYS D O   1 -0.223 0.723  -0.05  
ATOM   11877 C  CB  . LYS D 1 330 ? -21.989 78.125  -18.492 1    136.28 ? 319 LYS D CB  1 -0.202 0.716  -0.046 
ATOM   11878 C  CG  . LYS D 1 330 ? -20.516 78.23   -18.096 1    137.94 ? 319 LYS D CG  1 -0.188 0.717  -0.045 
ATOM   11879 C  CD  . LYS D 1 330 ? -19.998 79.661  -18.122 1    136.98 ? 319 LYS D CD  1 -0.183 0.73   -0.045 
ATOM   11880 C  CE  . LYS D 1 330 ? -19.632 80.122  -16.708 1    140.79 ? 319 LYS D CE  1 -0.18  0.734  -0.042 
ATOM   11881 N  NZ  . LYS D 1 330 ? -19.081 81.507  -16.65  1    142.56 ? 319 LYS D NZ  1 -0.175 0.747  -0.042 
ATOM   11882 N  N   . GLY D 1 331 ? -25.345 79.179  -17.965 1    138.2  ? 320 GLY D N   1 -0.232 0.726  -0.045 
ATOM   11883 C  CA  . GLY D 1 331 ? -26.677 79.018  -18.533 1    140.18 ? 320 GLY D CA  1 -0.244 0.724  -0.046 
ATOM   11884 C  C   . GLY D 1 331 ? -26.926 77.668  -19.17  1    144.8  ? 320 GLY D C   1 -0.247 0.712  -0.048 
ATOM   11885 O  O   . GLY D 1 331 ? -27.644 77.583  -20.176 1    145.26 ? 320 GLY D O   1 -0.253 0.711  -0.05  
ATOM   11886 N  N   . GLN D 1 332 ? -26.339 76.606  -18.62  1    146.69 ? 321 GLN D N   1 -0.241 0.702  -0.046 
ATOM   11887 C  CA  . GLN D 1 332 ? -26.533 75.241  -19.087 1    145.02 ? 321 GLN D CA  1 -0.243 0.69   -0.048 
ATOM   11888 C  C   . GLN D 1 332 ? -27.234 74.423  -18.008 1    144.79 ? 321 GLN D C   1 -0.25  0.682  -0.045 
ATOM   11889 O  O   . GLN D 1 332 ? -27.274 74.805  -16.833 1    142.56 ? 321 GLN D O   1 -0.25  0.686  -0.042 
ATOM   11890 C  CB  . GLN D 1 332 ? -25.194 74.582  -19.445 1    140.42 ? 321 GLN D CB  1 -0.231 0.683  -0.049 
ATOM   11891 C  CG  . GLN D 1 332 ? -24.123 75.565  -19.866 1    142    ? 321 GLN D CG  1 -0.221 0.692  -0.05  
ATOM   11892 C  CD  . GLN D 1 332 ? -22.721 75.041  -19.616 1    142.95 ? 321 GLN D CD  1 -0.208 0.688  -0.049 
ATOM   11893 O  OE1 . GLN D 1 332 ? -22.498 74.214  -18.73  1    130.33 ? 321 GLN D OE1 1 -0.206 0.68   -0.047 
ATOM   11894 N  NE2 . GLN D 1 332 ? -21.765 75.521  -20.405 1    149.24 ? 321 GLN D NE2 1 -0.199 0.692  -0.051 
ATOM   11895 N  N   . LYS D 1 333 ? -27.786 73.285  -18.416 1    142.26 ? 322 LYS D N   1 -0.255 0.672  -0.046 
ATOM   11896 C  CA  . LYS D 1 333 ? -28.409 72.354  -17.489 1    135.76 ? 322 LYS D CA  1 -0.26  0.663  -0.044 
ATOM   11897 C  C   . LYS D 1 333 ? -27.428 71.246  -17.111 1    135.06 ? 322 LYS D C   1 -0.251 0.653  -0.043 
ATOM   11898 O  O   . LYS D 1 333 ? -26.459 70.968  -17.825 1    134.72 ? 322 LYS D O   1 -0.242 0.65   -0.045 
ATOM   11899 C  CB  . LYS D 1 333 ? -29.685 71.756  -18.096 1    137.01 ? 322 LYS D CB  1 -0.272 0.658  -0.045 
ATOM   11900 C  CG  . LYS D 1 333 ? -30.79  72.77   -18.378 1    138.59 ? 322 LYS D CG  1 -0.282 0.667  -0.046 
ATOM   11901 C  CD  . LYS D 1 333 ? -31.244 73.473  -17.106 1    137.82 ? 322 LYS D CD  1 -0.286 0.673  -0.043 
ATOM   11902 C  CE  . LYS D 1 333 ? -32.395 74.429  -17.381 1    139.52 ? 322 LYS D CE  1 -0.297 0.682  -0.043 
ATOM   11903 N  NZ  . LYS D 1 333 ? -32.889 75.065  -16.128 1    141.33 ? 322 LYS D NZ  1 -0.301 0.688  -0.04  
ATOM   11904 N  N   . ILE D 1 334 ? -27.68  70.628  -15.956 1    136    ? 323 ILE D N   1 -0.254 0.647  -0.04  
ATOM   11905 C  CA  . ILE D 1 334 ? -26.945 69.45   -15.509 1    131.18 ? 323 ILE D CA  1 -0.247 0.636  -0.039 
ATOM   11906 C  C   . ILE D 1 334 ? -27.907 68.272  -15.462 1    127.91 ? 323 ILE D C   1 -0.256 0.626  -0.039 
ATOM   11907 O  O   . ILE D 1 334 ? -29.002 68.379  -14.893 1    127.2  ? 323 ILE D O   1 -0.266 0.627  -0.037 
ATOM   11908 C  CB  . ILE D 1 334 ? -26.276 69.654  -14.134 1    131.26 ? 323 ILE D CB  1 -0.241 0.638  -0.035 
ATOM   11909 C  CG1 . ILE D 1 334 ? -25.166 70.709  -14.226 1    131.76 ? 323 ILE D CG1 1 -0.231 0.648  -0.036 
ATOM   11910 C  CG2 . ILE D 1 334 ? -25.73  68.319  -13.599 1    123.19 ? 323 ILE D CG2 1 -0.236 0.626  -0.034 
ATOM   11911 C  CD1 . ILE D 1 334 ? -23.958 70.422  -13.352 1    121.94 ? 323 ILE D CD1 1 -0.22  0.645  -0.033 
ATOM   11912 N  N   . ALA D 1 335 ? -27.51  67.17   -16.089 1    124.21 ? 324 ALA D N   1 -0.252 0.616  -0.04  
ATOM   11913 C  CA  . ALA D 1 335 ? -28.132 65.872  -15.893 1    121.54 ? 324 ALA D CA  1 -0.258 0.604  -0.04  
ATOM   11914 C  C   . ALA D 1 335 ? -27.133 65.015  -15.129 1    123.97 ? 324 ALA D C   1 -0.249 0.596  -0.038 
ATOM   11915 O  O   . ALA D 1 335 ? -26.014 64.791  -15.607 1    123.35 ? 324 ALA D O   1 -0.238 0.594  -0.039 
ATOM   11916 C  CB  . ALA D 1 335 ? -28.518 65.221  -17.222 1    120.49 ? 324 ALA D CB  1 -0.261 0.598  -0.043 
ATOM   11917 N  N   . LEU D 1 336 ? -27.526 64.58   -13.931 1    121.69 ? 325 LEU D N   1 -0.252 0.592  -0.035 
ATOM   11918 C  CA  . LEU D 1 336 ? -26.708 63.757  -13.05  1    114.19 ? 325 LEU D CA  1 -0.245 0.584  -0.033 
ATOM   11919 C  C   . LEU D 1 336 ? -27.157 62.306  -13.16  1    112.91 ? 325 LEU D C   1 -0.249 0.571  -0.033 
ATOM   11920 O  O   . LEU D 1 336 ? -28.358 62.02   -13.217 1    116    ? 325 LEU D O   1 -0.26  0.568  -0.033 
ATOM   11921 C  CB  . LEU D 1 336 ? -26.834 64.239  -11.598 1    114    ? 325 LEU D CB  1 -0.246 0.589  -0.029 
ATOM   11922 C  CG  . LEU D 1 336 ? -26.234 63.485  -10.399 1    105.79 ? 325 LEU D CG  1 -0.24  0.582  -0.026 
ATOM   11923 C  CD1 . LEU D 1 336 ? -24.856 62.905  -10.673 1    110.64 ? 325 LEU D CD1 1 -0.228 0.576  -0.027 
ATOM   11924 C  CD2 . LEU D 1 336 ? -26.127 64.445  -9.244  1    105.28 ? 325 LEU D CD2 1 -0.239 0.591  -0.023 
ATOM   11925 N  N   . TYR D 1 337 ? -26.198 61.391  -13.194 1    104.61 ? 326 TYR D N   1 -0.24  0.563  -0.033 
ATOM   11926 C  CA  . TYR D 1 337 ? -26.526 59.976  -13.255 1    109.07 ? 326 TYR D CA  1 -0.243 0.55   -0.033 
ATOM   11927 C  C   . TYR D 1 337 ? -25.772 59.274  -12.141 1    110.42 ? 326 TYR D C   1 -0.236 0.543  -0.03  
ATOM   11928 O  O   . TYR D 1 337 ? -24.576 59.524  -11.943 1    110.88 ? 326 TYR D O   1 -0.225 0.545  -0.03  
ATOM   11929 C  CB  . TYR D 1 337 ? -26.213 59.381  -14.649 1    110    ? 326 TYR D CB  1 -0.24  0.544  -0.037 
ATOM   11930 C  CG  . TYR D 1 337 ? -27.191 59.885  -15.7   1    113.08 ? 326 TYR D CG  1 -0.249 0.549  -0.039 
ATOM   11931 C  CD1 . TYR D 1 337 ? -26.95  61.072  -16.391 1    114.17 ? 326 TYR D CD1 1 -0.247 0.56   -0.041 
ATOM   11932 C  CD2 . TYR D 1 337 ? -28.379 59.203  -15.968 1    112.6  ? 326 TYR D CD2 1 -0.26  0.543  -0.04  
ATOM   11933 C  CE1 . TYR D 1 337 ? -27.851 61.557  -17.325 1    116.21 ? 326 TYR D CE1 1 -0.255 0.564  -0.043 
ATOM   11934 C  CE2 . TYR D 1 337 ? -29.287 59.686  -16.917 1    115.79 ? 326 TYR D CE2 1 -0.268 0.547  -0.042 
ATOM   11935 C  CZ  . TYR D 1 337 ? -29.012 60.857  -17.582 1    116.23 ? 326 TYR D CZ  1 -0.266 0.558  -0.044 
ATOM   11936 O  OH  . TYR D 1 337 ? -29.917 61.314  -18.497 1    116.25 ? 326 TYR D OH  1 -0.274 0.562  -0.046 
ATOM   11937 N  N   . LEU D 1 338 ? -26.49  58.433  -11.384 1    106.03 ? 327 LEU D N   1 -0.243 0.535  -0.028 
ATOM   11938 C  CA  . LEU D 1 338 ? -25.945 57.705  -10.238 1    104.47 ? 327 LEU D CA  1 -0.238 0.529  -0.026 
ATOM   11939 C  C   . LEU D 1 338 ? -26.123 56.209  -10.474 1    104.62 ? 327 LEU D C   1 -0.239 0.515  -0.026 
ATOM   11940 O  O   . LEU D 1 338 ? -27.185 55.638  -10.173 1    101.96 ? 327 LEU D O   1 -0.249 0.51   -0.025 
ATOM   11941 C  CB  . LEU D 1 338 ? -26.614 58.153  -8.936  1    99.75  ? 327 LEU D CB  1 -0.244 0.533  -0.022 
ATOM   11942 C  CG  . LEU D 1 338 ? -26.269 59.563  -8.452  1    96.08  ? 327 LEU D CG  1 -0.241 0.546  -0.021 
ATOM   11943 C  CD1 . LEU D 1 338 ? -26.512 59.683  -6.932  1    110.65 ? 327 LEU D CD1 1 -0.243 0.547  -0.017 
ATOM   11944 C  CD2 . LEU D 1 338 ? -24.84  59.926  -8.828  1    98.3   ? 327 LEU D CD2 1 -0.228 0.549  -0.022 
ATOM   11945 N  N   . PRO D 1 339 ? -25.117 55.537  -11.053 1    106.15 ? 328 PRO D N   1 -0.23  0.509  -0.028 
ATOM   11946 C  CA  . PRO D 1 339 ? -25.133 54.071  -11.079 1    108.02 ? 328 PRO D CA  1 -0.23  0.496  -0.028 
ATOM   11947 C  C   . PRO D 1 339 ? -24.523 53.537  -9.788  1    107.46 ? 328 PRO D C   1 -0.225 0.491  -0.024 
ATOM   11948 O  O   . PRO D 1 339 ? -23.314 53.284  -9.673  1    105.65 ? 328 PRO D O   1 -0.214 0.488  -0.024 
ATOM   11949 C  CB  . PRO D 1 339 ? -24.294 53.732  -12.32  1    104.52 ? 328 PRO D CB  1 -0.223 0.492  -0.031 
ATOM   11950 C  CG  . PRO D 1 339 ? -23.314 54.871  -12.404 1    103.43 ? 328 PRO D CG  1 -0.214 0.503  -0.031 
ATOM   11951 C  CD  . PRO D 1 339 ? -24.036 56.095  -11.884 1    106.78 ? 328 PRO D CD  1 -0.22  0.514  -0.03  
ATOM   11952 N  N   . THR D 1 340 ? -25.364 53.406  -8.777  1    106.28 ? 329 THR D N   1 -0.232 0.489  -0.022 
ATOM   11953 C  CA  . THR D 1 340 ? -24.892 53.194  -7.425  1    103.09 ? 329 THR D CA  1 -0.228 0.487  -0.019 
ATOM   11954 C  C   . THR D 1 340 ? -24.969 51.717  -7.068  1    97.24  ? 329 THR D C   1 -0.229 0.474  -0.018 
ATOM   11955 O  O   . THR D 1 340 ? -25.998 51.072  -7.286  1    88.71  ? 329 THR D O   1 -0.238 0.468  -0.018 
ATOM   11956 C  CB  . THR D 1 340 ? -25.695 54.042  -6.443  1    101.88 ? 329 THR D CB  1 -0.235 0.495  -0.016 
ATOM   11957 O  OG1 . THR D 1 340 ? -25.221 55.396  -6.515  1    101.96 ? 329 THR D OG1 1 -0.231 0.508  -0.016 
ATOM   11958 C  CG2 . THR D 1 340 ? -25.512 53.535  -5.045  1    104.57 ? 329 THR D CG2 1 -0.234 0.491  -0.013 
ATOM   11959 N  N   . GLY D 1 341 ? -23.87  51.186  -6.535  1    103.32 ? 330 GLY D N   1 -0.219 0.469  -0.016 
ATOM   11960 C  CA  . GLY D 1 341 ? -23.849 49.87   -5.933  1    107.89 ? 330 GLY D CA  1 -0.219 0.457  -0.015 
ATOM   11961 C  C   . GLY D 1 341 ? -23.655 49.971  -4.428  1    107.89 ? 330 GLY D C   1 -0.217 0.458  -0.011 
ATOM   11962 O  O   . GLY D 1 341 ? -22.956 50.86   -3.935  1    108.65 ? 330 GLY D O   1 -0.21  0.466  -0.01  
ATOM   11963 N  N   . TRP D 1 342 ? -24.286 49.056  -3.688  1    101.5  ? 331 TRP D N   1 -0.223 0.45   -0.009 
ATOM   11964 C  CA  . TRP D 1 342 ? -24.088 49.012  -2.242  1    109.95 ? 331 TRP D CA  1 -0.221 0.449  -0.006 
ATOM   11965 C  C   . TRP D 1 342 ? -23.008 48.033  -1.823  1    110.33 ? 331 TRP D C   1 -0.211 0.44   -0.005 
ATOM   11966 O  O   . TRP D 1 342 ? -22.647 48.005  -0.637  1    98.79  ? 331 TRP D O   1 -0.208 0.44   -0.002 
ATOM   11967 C  CB  . TRP D 1 342 ? -25.404 48.686  -1.517  1    100.91 ? 331 TRP D CB  1 -0.233 0.446  -0.004 
ATOM   11968 C  CG  . TRP D 1 342 ? -26.14  49.967  -1.339  1    106.76 ? 331 TRP D CG  1 -0.24  0.458  -0.003 
ATOM   11969 C  CD1 . TRP D 1 342 ? -25.585 51.154  -0.94   1    113.22 ? 331 TRP D CD1 1 -0.234 0.469  -0.002 
ATOM   11970 C  CD2 . TRP D 1 342 ? -27.514 50.256  -1.647  1    100.89 ? 331 TRP D CD2 1 -0.252 0.461  -0.004 
ATOM   11971 N  NE1 . TRP D 1 342 ? -26.536 52.151  -0.94   1    114.38 ? 331 TRP D NE1 1 -0.243 0.478  -0.002 
ATOM   11972 C  CE2 . TRP D 1 342 ? -27.727 51.63   -1.367  1    103.37 ? 331 TRP D CE2 1 -0.254 0.473  -0.003 
ATOM   11973 C  CE3 . TRP D 1 342 ? -28.592 49.489  -2.109  1    85.67  ? 331 TRP D CE3 1 -0.262 0.454  -0.005 
ATOM   11974 C  CZ2 . TRP D 1 342 ? -28.965 52.246  -1.539  1    99.96  ? 331 TRP D CZ2 1 -0.265 0.479  -0.004 
ATOM   11975 C  CZ3 . TRP D 1 342 ? -29.821 50.106  -2.275  1    81.55  ? 331 TRP D CZ3 1 -0.273 0.459  -0.006 
ATOM   11976 C  CH2 . TRP D 1 342 ? -29.999 51.469  -1.992  1    90.67  ? 331 TRP D CH2 1 -0.275 0.472  -0.005 
ATOM   11977 N  N   . ASP D 1 343 ? -22.475 47.254  -2.775  1    107.96 ? 332 ASP D N   1 -0.206 0.433  -0.007 
ATOM   11978 C  CA  . ASP D 1 343 ? -21.42  46.293  -2.495  1    107.29 ? 332 ASP D CA  1 -0.196 0.424  -0.006 
ATOM   11979 C  C   . ASP D 1 343 ? -20.125 46.959  -2.06   1    104.83 ? 332 ASP D C   1 -0.184 0.43   -0.005 
ATOM   11980 O  O   . ASP D 1 343 ? -19.193 46.247  -1.675  1    105.7  ? 332 ASP D O   1 -0.176 0.424  -0.004 
ATOM   11981 C  CB  . ASP D 1 343 ? -21.167 45.386  -3.714  1    108.24 ? 332 ASP D CB  1 -0.194 0.416  -0.009 
ATOM   11982 C  CG  . ASP D 1 343 ? -21.019 46.158  -5.032  1    111.14 ? 332 ASP D CG  1 -0.193 0.423  -0.013 
ATOM   11983 O  OD1 . ASP D 1 343 ? -20.985 47.41   -5.017  1    110.9  ? 332 ASP D OD1 1 -0.192 0.434  -0.013 
ATOM   11984 O  OD2 . ASP D 1 343 ? -20.928 45.496  -6.096  1    113.41 ? 332 ASP D OD2 1 -0.192 0.417  -0.015 
ATOM   11985 N  N   . SER D 1 344 ? -20.042 48.294  -2.116  1    101.7  ? 333 SER D N   1 -0.184 0.443  -0.005 
ATOM   11986 C  CA  . SER D 1 344 ? -18.927 49.047  -1.554  1    105.15 ? 333 SER D CA  1 -0.173 0.449  -0.004 
ATOM   11987 C  C   . SER D 1 344 ? -19.098 49.35   -0.056  1    108.81 ? 333 SER D C   1 -0.175 0.452  -0.0   
ATOM   11988 O  O   . SER D 1 344 ? -18.412 50.241  0.459   1    106.2  ? 333 SER D O   1 -0.169 0.46   0.001  
ATOM   11989 C  CB  . SER D 1 344 ? -18.723 50.355  -2.324  1    98.29  ? 333 SER D CB  1 -0.172 0.461  -0.006 
ATOM   11990 O  OG  . SER D 1 344 ? -19.938 51.075  -2.471  1    95.1   ? 333 SER D OG  1 -0.183 0.468  -0.006 
ATOM   11991 N  N   . HIS D 1 345 ? -19.967 48.635  0.652   1    104.15 ? 334 HIS D N   1 -0.183 0.446  0.002  
ATOM   11992 C  CA  . HIS D 1 345 ? -20.25  48.911  2.054   1    109.18 ? 334 HIS D CA  1 -0.186 0.448  0.005  
ATOM   11993 C  C   . HIS D 1 345 ? -19.532 47.918  2.967   1    113.12 ? 334 HIS D C   1 -0.179 0.439  0.007  
ATOM   11994 O  O   . HIS D 1 345 ? -19.353 46.744  2.623   1    115.21 ? 334 HIS D O   1 -0.177 0.428  0.007  
ATOM   11995 C  CB  . HIS D 1 345 ? -21.758 48.874  2.324   1    107.99 ? 334 HIS D CB  1 -0.199 0.448  0.006  
ATOM   11996 C  CG  . HIS D 1 345 ? -22.13  49.327  3.696   1    112.01 ? 334 HIS D CG  1 -0.203 0.452  0.009  
ATOM   11997 N  ND1 . HIS D 1 345 ? -22.998 48.63   4.506   1    117.8  ? 334 HIS D ND1 1 -0.211 0.446  0.011  
ATOM   11998 C  CD2 . HIS D 1 345 ? -21.72  50.395  4.419   1    113.18 ? 334 HIS D CD2 1 -0.199 0.462  0.011  
ATOM   11999 C  CE1 . HIS D 1 345 ? -23.113 49.254  5.666   1    111.62 ? 334 HIS D CE1 1 -0.212 0.451  0.014  
ATOM   12000 N  NE2 . HIS D 1 345 ? -22.352 50.331  5.635   1    108.41 ? 334 HIS D NE2 1 -0.205 0.461  0.014  
ATOM   12001 N  N   . GLU D 1 346 ? -19.139 48.399  4.153   1    113.98 ? 335 GLU D N   1 -0.175 0.444  0.01   
ATOM   12002 C  CA  . GLU D 1 346 ? -18.288 47.609  5.043   1    113.19 ? 335 GLU D CA  1 -0.168 0.436  0.013  
ATOM   12003 C  C   . GLU D 1 346 ? -18.977 46.347  5.533   1    111.51 ? 335 GLU D C   1 -0.174 0.425  0.014  
ATOM   12004 O  O   . GLU D 1 346 ? -18.302 45.362  5.839   1    113.5  ? 335 GLU D O   1 -0.168 0.416  0.015  
ATOM   12005 C  CB  . GLU D 1 346 ? -17.858 48.447  6.238   1    112.85 ? 335 GLU D CB  1 -0.164 0.444  0.016  
ATOM   12006 C  CG  . GLU D 1 346 ? -19.016 48.869  7.087   1    111.65 ? 335 GLU D CG  1 -0.174 0.448  0.018  
ATOM   12007 C  CD  . GLU D 1 346 ? -18.583 49.664  8.28    1    116.39 ? 335 GLU D CD  1 -0.17  0.455  0.021  
ATOM   12008 O  OE1 . GLU D 1 346 ? -17.601 50.437  8.151   1    110.85 ? 335 GLU D OE1 1 -0.161 0.462  0.02   
ATOM   12009 O  OE2 . GLU D 1 346 ? -19.226 49.493  9.344   1    123.09 ? 335 GLU D OE2 1 -0.176 0.454  0.023  
ATOM   12010 N  N   . ASP D 1 347 ? -20.303 46.351  5.626   1    111.25 ? 336 ASP D N   1 -0.186 0.425  0.014  
ATOM   12011 C  CA  . ASP D 1 347 ? -21.049 45.158  6.004   1    114.88 ? 336 ASP D CA  1 -0.193 0.414  0.015  
ATOM   12012 C  C   . ASP D 1 347 ? -21.378 44.245  4.82    1    115.7  ? 336 ASP D C   1 -0.196 0.405  0.012  
ATOM   12013 O  O   . ASP D 1 347 ? -22.109 43.26   5.003   1    112.15 ? 336 ASP D O   1 -0.203 0.396  0.012  
ATOM   12014 C  CB  . ASP D 1 347 ? -22.336 45.552  6.729   1    110.25 ? 336 ASP D CB  1 -0.205 0.417  0.017  
ATOM   12015 C  CG  . ASP D 1 347 ? -22.067 46.24   8.04    1    120.3  ? 336 ASP D CG  1 -0.202 0.424  0.02   
ATOM   12016 O  OD1 . ASP D 1 347 ? -21.187 45.756  8.801   1    124.82 ? 336 ASP D OD1 1 -0.194 0.419  0.022  
ATOM   12017 O  OD2 . ASP D 1 347 ? -22.724 47.272  8.302   1    119.67 ? 336 ASP D OD2 1 -0.208 0.433  0.021  
ATOM   12018 N  N   . GLU D 1 348 ? -20.868 44.55   3.621   1    110.22 ? 337 GLU D N   1 -0.191 0.408  0.009  
ATOM   12019 C  CA  . GLU D 1 348 ? -21.042 43.657  2.478   1    115.31 ? 337 GLU D CA  1 -0.193 0.4    0.006  
ATOM   12020 C  C   . GLU D 1 348 ? -20.308 42.341  2.71    1    117.57 ? 337 GLU D C   1 -0.186 0.388  0.007  
ATOM   12021 O  O   . GLU D 1 348 ? -19.192 42.317  3.239   1    116.39 ? 337 GLU D O   1 -0.176 0.388  0.008  
ATOM   12022 C  CB  . GLU D 1 348 ? -20.533 44.313  1.187   1    114.94 ? 337 GLU D CB  1 -0.188 0.406  0.003  
ATOM   12023 C  CG  . GLU D 1 348 ? -20.514 43.386  -0.029  1    106.11 ? 337 GLU D CG  1 -0.188 0.398  -0.0   
ATOM   12024 C  CD  . GLU D 1 348 ? -21.898 42.869  -0.372  1    108.88 ? 337 GLU D CD  1 -0.201 0.393  -0.001 
ATOM   12025 O  OE1 . GLU D 1 348 ? -22.653 43.607  -1.046  1    107.67 ? 337 GLU D OE1 1 -0.208 0.4    -0.003 
ATOM   12026 O  OE2 . GLU D 1 348 ? -22.239 41.736  0.045   1    107.46 ? 337 GLU D OE2 1 -0.204 0.382  0.0    
ATOM   12027 N  N   . THR D 1 349 ? -20.945 41.24   2.3     1    117.11 ? 338 THR D N   1 -0.192 0.378  0.006  
ATOM   12028 C  CA  . THR D 1 349 ? -20.411 39.899  2.488   1    116.27 ? 338 THR D CA  1 -0.187 0.366  0.006  
ATOM   12029 C  C   . THR D 1 349 ? -20.115 39.175  1.18    1    119.18 ? 338 THR D C   1 -0.184 0.359  0.003  
ATOM   12030 O  O   . THR D 1 349 ? -19.694 38.009  1.219   1    115.08 ? 338 THR D O   1 -0.18  0.348  0.003  
ATOM   12031 C  CB  . THR D 1 349 ? -21.391 39.062  3.319   1    117.26 ? 338 THR D CB  1 -0.196 0.358  0.008  
ATOM   12032 O  OG1 . THR D 1 349 ? -22.426 38.559  2.465   1    124.02 ? 338 THR D OG1 1 -0.206 0.353  0.006  
ATOM   12033 C  CG2 . THR D 1 349 ? -22.023 39.922  4.389   1    115.61 ? 338 THR D CG2 1 -0.202 0.366  0.011  
ATOM   12034 N  N   . ALA D 1 350 ? -20.319 39.826  0.033   1    116.59 ? 339 ALA D N   1 -0.186 0.365  0.0    
ATOM   12035 C  CA  . ALA D 1 350 ? -20.079 39.191  -1.257  1    117.67 ? 339 ALA D CA  1 -0.184 0.359  -0.003 
ATOM   12036 C  C   . ALA D 1 350 ? -18.589 39.071  -1.542  1    119.46 ? 339 ALA D C   1 -0.17  0.358  -0.004 
ATOM   12037 O  O   . ALA D 1 350 ? -17.783 39.912  -1.136  1    118.12 ? 339 ALA D O   1 -0.163 0.366  -0.003 
ATOM   12038 C  CB  . ALA D 1 350 ? -20.746 39.981  -2.391  1    112.14 ? 339 ALA D CB  1 -0.19  0.366  -0.006 
ATOM   12039 N  N   . TYR D 1 351 ? -18.24  38.017  -2.283  1    127.14 ? 340 TYR D N   1 -0.167 0.348  -0.006 
ATOM   12040 C  CA  . TYR D 1 351 ? -16.859 37.797  -2.704  1    128.4  ? 340 TYR D CA  1 -0.154 0.346  -0.007 
ATOM   12041 C  C   . TYR D 1 351 ? -16.313 38.99   -3.485  1    122.15 ? 340 TYR D C   1 -0.149 0.357  -0.009 
ATOM   12042 O  O   . TYR D 1 351 ? -15.201 39.465  -3.227  1    116.05 ? 340 TYR D O   1 -0.139 0.362  -0.008 
ATOM   12043 C  CB  . TYR D 1 351 ? -16.783 36.528  -3.559  1    132.44 ? 340 TYR D CB  1 -0.154 0.335  -0.009 
ATOM   12044 C  CG  . TYR D 1 351 ? -15.382 36.12   -3.969  1    134.24 ? 340 TYR D CG  1 -0.141 0.331  -0.01  
ATOM   12045 C  CD1 . TYR D 1 351 ? -14.508 35.57   -3.038  1    135.76 ? 340 TYR D CD1 1 -0.133 0.326  -0.008 
ATOM   12046 C  CD2 . TYR D 1 351 ? -14.939 36.265  -5.282  1    128.13 ? 340 TYR D CD2 1 -0.137 0.332  -0.013 
ATOM   12047 C  CE1 . TYR D 1 351 ? -13.227 35.185  -3.396  1    137.66 ? 340 TYR D CE1 1 -0.121 0.322  -0.008 
ATOM   12048 C  CE2 . TYR D 1 351 ? -13.648 35.884  -5.647  1    129.86 ? 340 TYR D CE2 1 -0.125 0.329  -0.014 
ATOM   12049 C  CZ  . TYR D 1 351 ? -12.798 35.343  -4.692  1    133.05 ? 340 TYR D CZ  1 -0.117 0.324  -0.012 
ATOM   12050 O  OH  . TYR D 1 351 ? -11.515 34.952  -5.004  1    129.14 ? 340 TYR D OH  1 -0.106 0.32   -0.012 
ATOM   12051 N  N   . CYS D 1 352 ? -17.087 39.485  -4.451  1    124    ? 341 CYS D N   1 -0.157 0.362  -0.011 
ATOM   12052 C  CA  . CYS D 1 352 ? -16.613 40.461  -5.426  1    123.16 ? 341 CYS D CA  1 -0.152 0.371  -0.014 
ATOM   12053 C  C   . CYS D 1 352 ? -16.528 41.87   -4.869  1    121.55 ? 341 CYS D C   1 -0.151 0.384  -0.012 
ATOM   12054 O  O   . CYS D 1 352 ? -16.386 42.821  -5.646  1    117.78 ? 341 CYS D O   1 -0.15  0.392  -0.014 
ATOM   12055 C  CB  . CYS D 1 352 ? -17.514 40.424  -6.654  1    112.3  ? 341 CYS D CB  1 -0.161 0.37   -0.017 
ATOM   12056 S  SG  . CYS D 1 352 ? -17.689 38.732  -7.257  1    138.32 ? 341 CYS D SG  1 -0.162 0.355  -0.018 
ATOM   12057 N  N   . GLY D 1 353 ? -16.608 42.019  -3.547  1    124.54 ? 342 GLY D N   1 -0.152 0.385  -0.009 
ATOM   12058 C  CA  . GLY D 1 353 ? -16.368 43.299  -2.906  1    123.57 ? 342 GLY D CA  1 -0.15  0.397  -0.007 
ATOM   12059 C  C   . GLY D 1 353 ? -15.348 43.196  -1.791  1    118.13 ? 342 GLY D C   1 -0.141 0.396  -0.004 
ATOM   12060 O  O   . GLY D 1 353 ? -14.46  44.047  -1.668  1    113.28 ? 342 GLY D O   1 -0.133 0.404  -0.004 
ATOM   12061 N  N   . LYS D 1 354 ? -15.447 42.133  -0.994  1    122.93 ? 343 LYS D N   1 -0.142 0.386  -0.002 
ATOM   12062 C  CA  . LYS D 1 354 ? -14.674 42.004  0.238   1    127.35 ? 343 LYS D CA  1 -0.134 0.385  0.001  
ATOM   12063 C  C   . LYS D 1 354 ? -13.385 41.217  0.086   1    131.24 ? 343 LYS D C   1 -0.123 0.378  0.0    
ATOM   12064 O  O   . LYS D 1 354 ? -12.455 41.437  0.865   1    137.66 ? 343 LYS D O   1 -0.114 0.38   0.002  
ATOM   12065 C  CB  . LYS D 1 354 ? -15.517 41.342  1.33    1    114.83 ? 343 LYS D CB  1 -0.142 0.379  0.003  
ATOM   12066 C  CG  . LYS D 1 354 ? -16.377 42.319  2.07    1    115.84 ? 343 LYS D CG  1 -0.15  0.388  0.005  
ATOM   12067 C  CD  . LYS D 1 354 ? -15.526 43.233  2.928   1    129.51 ? 343 LYS D CD  1 -0.142 0.396  0.007  
ATOM   12068 C  CE  . LYS D 1 354 ? -16.136 43.406  4.32    1    122.37 ? 343 LYS D CE  1 -0.148 0.398  0.011  
ATOM   12069 N  NZ  . LYS D 1 354 ? -17.519 43.956  4.224   1    116.25 ? 343 LYS D NZ  1 -0.161 0.403  0.011  
ATOM   12070 N  N   . PHE D 1 355 ? -13.298 40.302  -0.874  1    130.75 ? 344 PHE D N   1 -0.122 0.369  -0.002 
ATOM   12071 C  CA  . PHE D 1 355 ? -12.109 39.468  -1.011  1    133.3  ? 344 PHE D CA  1 -0.111 0.362  -0.003 
ATOM   12072 C  C   . PHE D 1 355 ? -11.009 40.274  -1.689  1    136.37 ? 344 PHE D C   1 -0.101 0.369  -0.004 
ATOM   12073 O  O   . PHE D 1 355 ? -11.059 40.514  -2.901  1    131.41 ? 344 PHE D O   1 -0.101 0.371  -0.007 
ATOM   12074 C  CB  . PHE D 1 355 ? -12.426 38.202  -1.8    1    137.02 ? 344 PHE D CB  1 -0.114 0.35   -0.004 
ATOM   12075 C  CG  . PHE D 1 355 ? -11.243 37.301  -1.987  1    139.4  ? 344 PHE D CG  1 -0.103 0.342  -0.005 
ATOM   12076 C  CD1 . PHE D 1 355 ? -10.887 36.394  -1.001  1    139.18 ? 344 PHE D CD1 1 -0.1   0.334  -0.002 
ATOM   12077 C  CD2 . PHE D 1 355 ? -10.483 37.363  -3.151  1    138.1  ? 344 PHE D CD2 1 -0.096 0.342  -0.008 
ATOM   12078 C  CE1 . PHE D 1 355 ? -9.791  35.564  -1.172  1    143.43 ? 344 PHE D CE1 1 -0.09  0.326  -0.003 
ATOM   12079 C  CE2 . PHE D 1 355 ? -9.388  36.538  -3.331  1    135.74 ? 344 PHE D CE2 1 -0.086 0.335  -0.008 
ATOM   12080 C  CZ  . PHE D 1 355 ? -9.042  35.636  -2.348  1    140.08 ? 344 PHE D CZ  1 -0.083 0.327  -0.006 
ATOM   12081 N  N   . VAL D 1 356 ? -10.012 40.685  -0.907  1    138.15 ? 345 VAL D N   1 -0.092 0.373  -0.002 
ATOM   12082 C  CA  . VAL D 1 356 ? -8.884  41.464  -1.4    1    141.44 ? 345 VAL D CA  1 -0.081 0.38   -0.003 
ATOM   12083 C  C   . VAL D 1 356 ? -7.602  40.693  -1.126  1    146.47 ? 345 VAL D C   1 -0.07  0.373  -0.003 
ATOM   12084 O  O   . VAL D 1 356 ? -7.519  39.908  -0.17   1    144.25 ? 345 VAL D O   1 -0.069 0.366  -0.0   
ATOM   12085 C  CB  . VAL D 1 356 ? -8.83   42.874  -0.774  1    139.25 ? 345 VAL D CB  1 -0.081 0.393  -0.002 
ATOM   12086 C  CG1 . VAL D 1 356 ? -10.193 43.549  -0.876  1    136.76 ? 345 VAL D CG1 1 -0.093 0.399  -0.002 
ATOM   12087 C  CG2 . VAL D 1 356 ? -8.359  42.807  0.677   1    144.71 ? 345 VAL D CG2 1 -0.077 0.392  0.002  
ATOM   12088 N  N   . ASN D 1 357 ? -6.589  40.958  -1.966  1    153.51 ? 346 ASN D N   1 -0.06  0.375  -0.005 
ATOM   12089 C  CA  . ASN D 1 357 ? -5.348  40.194  -2.131  1    155.34 ? 346 ASN D CA  1 -0.049 0.368  -0.005 
ATOM   12090 C  C   . ASN D 1 357 ? -5.282  38.914  -1.298  1    154.44 ? 346 ASN D C   1 -0.048 0.357  -0.003 
ATOM   12091 O  O   . ASN D 1 357 ? -4.503  38.814  -0.343  1    154.12 ? 346 ASN D O   1 -0.041 0.356  -0.001 
ATOM   12092 C  CB  . ASN D 1 357 ? -4.129  41.085  -1.839  1    156.31 ? 346 ASN D CB  1 -0.038 0.377  -0.005 
ATOM   12093 C  CG  . ASN D 1 357 ? -4.211  41.784  -0.491  1    156.37 ? 346 ASN D CG  1 -0.039 0.383  -0.001 
ATOM   12094 O  OD1 . ASN D 1 357 ? -5.251  42.328  -0.119  1    155.18 ? 346 ASN D OD1 1 -0.048 0.388  -0.0   
ATOM   12095 N  ND2 . ASN D 1 357 ? -3.103  41.776  0.248   1    163.17 ? 346 ASN D ND2 1 -0.028 0.383  0.001  
ATOM   12096 N  N   . GLY D 1 358 ? -6.112  37.933  -1.655  1    151.05 ? 347 GLY D N   1 -0.056 0.348  -0.004 
ATOM   12097 C  CA  . GLY D 1 358 ? -6.074  36.623  -1.041  1    146.73 ? 347 GLY D CA  1 -0.056 0.336  -0.003 
ATOM   12098 C  C   . GLY D 1 358 ? -6.849  36.462  0.25    1    144.03 ? 347 GLY D C   1 -0.063 0.334  0.001  
ATOM   12099 O  O   . GLY D 1 358 ? -6.911  35.341  0.769   1    145.91 ? 347 GLY D O   1 -0.063 0.324  0.002  
ATOM   12100 N  N   . ARG D 1 359 ? -7.453  37.524  0.784   1    143.03 ? 348 ARG D N   1 -0.068 0.344  0.002  
ATOM   12101 C  CA  . ARG D 1 359 ? -8.043  37.469  2.118   1    146.05 ? 348 ARG D CA  1 -0.074 0.343  0.005  
ATOM   12102 C  C   . ARG D 1 359 ? -9.426  38.101  2.126   1    140.1  ? 348 ARG D C   1 -0.086 0.349  0.005  
ATOM   12103 O  O   . ARG D 1 359 ? -9.601  39.209  1.61    1    140.6  ? 348 ARG D O   1 -0.088 0.359  0.004  
ATOM   12104 C  CB  . ARG D 1 359 ? -7.149  38.189  3.138   1    148.27 ? 348 ARG D CB  1 -0.066 0.35   0.008  
ATOM   12105 C  CG  . ARG D 1 359 ? -5.771  37.574  3.334   1    149.78 ? 348 ARG D CG  1 -0.053 0.344  0.008  
ATOM   12106 C  CD  . ARG D 1 359 ? -5.863  36.264  4.091   1    147.09 ? 348 ARG D CD  1 -0.054 0.332  0.01   
ATOM   12107 N  NE  . ARG D 1 359 ? -4.839  36.169  5.124   1    153.46 ? 348 ARG D NE  1 -0.044 0.331  0.013  
ATOM   12108 C  CZ  . ARG D 1 359 ? -4.666  35.113  5.906   1    156.46 ? 348 ARG D CZ  1 -0.043 0.322  0.015  
ATOM   12109 N  NH1 . ARG D 1 359 ? -5.415  34.029  5.778   1    149.23 ? 348 ARG D NH1 1 -0.05  0.312  0.014  
ATOM   12110 N  NH2 . ARG D 1 359 ? -3.721  35.147  6.843   1    161.4  ? 348 ARG D NH2 1 -0.034 0.322  0.017  
ATOM   12111 N  N   . MET D 1 360 ? -10.401 37.409  2.725   1    131.96 ? 349 MET D N   1 -0.095 0.343  0.007  
ATOM   12112 C  CA  . MET D 1 360 ? -11.677 38.052  3.011   1    127.38 ? 349 MET D CA  1 -0.107 0.349  0.008  
ATOM   12113 C  C   . MET D 1 360 ? -11.426 39.207  3.969   1    132.06 ? 349 MET D C   1 -0.105 0.359  0.01   
ATOM   12114 O  O   . MET D 1 360 ? -11.04  38.983  5.121   1    142.65 ? 349 MET D O   1 -0.101 0.357  0.013  
ATOM   12115 C  CB  . MET D 1 360 ? -12.688 37.063  3.596   1    125.6  ? 349 MET D CB  1 -0.116 0.34   0.009  
ATOM   12116 C  CG  . MET D 1 360 ? -13.422 36.192  2.569   1    139.71 ? 349 MET D CG  1 -0.123 0.332  0.006  
ATOM   12117 S  SD  . MET D 1 360 ? -14.244 37.086  1.199   1    146.2  ? 349 MET D SD  1 -0.131 0.34   0.003  
ATOM   12118 C  CE  . MET D 1 360 ? -15.861 36.299  1.176   1    129.88 ? 349 MET D CE  1 -0.145 0.333  0.003  
ATOM   12119 N  N   . MET D 1 361 ? -11.631 40.439  3.506   1    126.62 ? 350 MET D N   1 -0.107 0.371  0.009  
ATOM   12120 C  CA  . MET D 1 361 ? -11.252 41.625  4.275   1    130.13 ? 350 MET D CA  1 -0.103 0.381  0.011  
ATOM   12121 C  C   . MET D 1 361 ? -11.905 41.653  5.66    1    132.7  ? 350 MET D C   1 -0.109 0.382  0.014  
ATOM   12122 O  O   . MET D 1 361 ? -13.126 41.518  5.795   1    133.21 ? 350 MET D O   1 -0.12  0.38   0.014  
ATOM   12123 C  CB  . MET D 1 361 ? -11.634 42.867  3.48    1    125.35 ? 350 MET D CB  1 -0.107 0.393  0.009  
ATOM   12124 C  CG  . MET D 1 361 ? -11.205 44.189  4.06    1    125.09 ? 350 MET D CG  1 -0.103 0.405  0.01   
ATOM   12125 S  SD  . MET D 1 361 ? -12.06  45.546  3.211   1    135.91 ? 350 MET D SD  1 -0.111 0.417  0.008  
ATOM   12126 C  CE  . MET D 1 361 ? -11.113 45.736  1.708   1    129.86 ? 350 MET D CE  1 -0.102 0.419  0.004  
ATOM   12127 N  N   . GLY D 1 362 ? -11.077 41.845  6.702   1    130.37 ? 351 GLY D N   1 -0.102 0.383  0.017  
ATOM   12128 C  CA  . GLY D 1 362 ? -11.582 41.874  8.06    1    130.25 ? 351 GLY D CA  1 -0.106 0.384  0.02   
ATOM   12129 C  C   . GLY D 1 362 ? -12.339 43.15   8.396   1    129.35 ? 351 GLY D C   1 -0.113 0.395  0.021  
ATOM   12130 O  O   . GLY D 1 362 ? -12.253 44.159  7.692   1    129.78 ? 351 GLY D O   1 -0.112 0.405  0.019  
ATOM   12131 N  N   . LYS D 1 363 ? -13.093 43.093  9.503   1    129.12 ? 352 LYS D N   1 -0.12  0.395  0.024  
ATOM   12132 C  CA  . LYS D 1 363 ? -13.918 44.235  9.911   1    131.01 ? 352 LYS D CA  1 -0.128 0.405  0.025  
ATOM   12133 C  C   . LYS D 1 363 ? -13.075 45.488  10.101  1    129.74 ? 352 LYS D C   1 -0.12  0.417  0.025  
ATOM   12134 O  O   . LYS D 1 363 ? -13.506 46.599  9.763   1    128.5  ? 352 LYS D O   1 -0.124 0.427  0.024  
ATOM   12135 C  CB  . LYS D 1 363 ? -14.683 43.914  11.203  1    123.41 ? 352 LYS D CB  1 -0.135 0.402  0.028  
ATOM   12136 C  CG  . LYS D 1 363 ? -16.059 43.262  11.007  1    131.06 ? 352 LYS D CG  1 -0.147 0.396  0.027  
ATOM   12137 C  CD  . LYS D 1 363 ? -17.2   44.088  11.628  1    132.46 ? 352 LYS D CD  1 -0.158 0.404  0.029  
ATOM   12138 C  CE  . LYS D 1 363 ? -17.546 45.317  10.775  1    139.05 ? 352 LYS D CE  1 -0.161 0.415  0.027  
ATOM   12139 N  NZ  . LYS D 1 363 ? -18.599 46.187  11.392  1    137.02 ? 352 LYS D NZ  1 -0.17  0.423  0.028  
ATOM   12140 N  N   . THR D 1 364 ? -11.864 45.327  10.628  1    133.26 ? 353 THR D N   1 -0.109 0.415  0.027  
ATOM   12141 C  CA  . THR D 1 364 ? -11.023 46.483  10.912  1    134.15 ? 353 THR D CA  1 -0.101 0.426  0.027  
ATOM   12142 C  C   . THR D 1 364 ? -10.539 47.138  9.621   1    131.08 ? 353 THR D C   1 -0.097 0.432  0.024  
ATOM   12143 O  O   . THR D 1 364 ? -10.503 48.372  9.524   1    130.03 ? 353 THR D O   1 -0.096 0.443  0.024  
ATOM   12144 C  CB  . THR D 1 364 ? -9.858  46.056  11.821  1    136.96 ? 353 THR D CB  1 -0.09  0.422  0.03   
ATOM   12145 O  OG1 . THR D 1 364 ? -9.531  47.118  12.731  1    128.51 ? 353 THR D OG1 1 -0.087 0.432  0.032  
ATOM   12146 C  CG2 . THR D 1 364 ? -8.602  45.632  11.012  1    133.03 ? 353 THR D CG2 1 -0.079 0.418  0.027  
ATOM   12147 N  N   . ALA D 1 365 ? -10.208 46.33   8.604   1    132.71 ? 354 ALA D N   1 -0.094 0.425  0.021  
ATOM   12148 C  CA  . ALA D 1 365 ? -9.777  46.876  7.321   1    128.23 ? 354 ALA D CA  1 -0.09  0.43   0.018  
ATOM   12149 C  C   . ALA D 1 365 ? -10.955 47.448  6.552   1    125.41 ? 354 ALA D C   1 -0.1   0.435  0.016  
ATOM   12150 O  O   . ALA D 1 365 ? -10.84  48.51   5.933   1    124.45 ? 354 ALA D O   1 -0.099 0.445  0.015  
ATOM   12151 C  CB  . ALA D 1 365 ? -9.079  45.797  6.494   1    125.78 ? 354 ALA D CB  1 -0.083 0.42   0.016  
ATOM   12152 N  N   . ALA D 1 366 ? -12.102 46.763  6.602   1    127.37 ? 355 ALA D N   1 -0.111 0.429  0.016  
ATOM   12153 C  CA  . ALA D 1 366 ? -13.277 47.206  5.855   1    126.24 ? 355 ALA D CA  1 -0.122 0.433  0.015  
ATOM   12154 C  C   . ALA D 1 366 ? -13.795 48.548  6.36    1    125.31 ? 355 ALA D C   1 -0.126 0.445  0.016  
ATOM   12155 O  O   . ALA D 1 366 ? -14.265 49.368  5.565   1    121.45 ? 355 ALA D O   1 -0.131 0.452  0.014  
ATOM   12156 C  CB  . ALA D 1 366 ? -14.372 46.141  5.917   1    126.27 ? 355 ALA D CB  1 -0.132 0.423  0.015  
ATOM   12157 N  N   . HIS D 1 367 ? -13.727 48.797  7.674   1    130.96 ? 356 HIS D N   1 -0.126 0.447  0.019  
ATOM   12158 C  CA  . HIS D 1 367 ? -14.072 50.124  8.175   1    128.76 ? 356 HIS D CA  1 -0.129 0.459  0.02   
ATOM   12159 C  C   . HIS D 1 367 ? -13.246 51.203  7.493   1    126.6  ? 356 HIS D C   1 -0.121 0.469  0.019  
ATOM   12160 O  O   . HIS D 1 367 ? -13.646 52.371  7.494   1    127.66 ? 356 HIS D O   1 -0.125 0.48   0.019  
ATOM   12161 C  CB  . HIS D 1 367 ? -13.871 50.2    9.695   1    129.23 ? 356 HIS D CB  1 -0.127 0.46   0.024  
ATOM   12162 C  CG  . HIS D 1 367 ? -14.123 51.561  10.285  1    136.52 ? 356 HIS D CG  1 -0.129 0.473  0.026  
ATOM   12163 N  ND1 . HIS D 1 367 ? -13.627 52.727  9.735   1    132.24 ? 356 HIS D ND1 1 -0.125 0.483  0.024  
ATOM   12164 C  CD2 . HIS D 1 367 ? -14.791 51.935  11.404  1    146.44 ? 356 HIS D CD2 1 -0.136 0.476  0.028  
ATOM   12165 C  CE1 . HIS D 1 367 ? -13.995 53.757  10.473  1    136.59 ? 356 HIS D CE1 1 -0.128 0.493  0.026  
ATOM   12166 N  NE2 . HIS D 1 367 ? -14.697 53.305  11.497  1    147    ? 356 HIS D NE2 1 -0.135 0.488  0.029  
ATOM   12167 N  N   . GLN D 1 368 ? -12.099 50.851  6.931   1    122.39 ? 357 GLN D N   1 -0.111 0.466  0.017  
ATOM   12168 C  CA  . GLN D 1 368 ? -11.259 51.86   6.311   1    124.07 ? 357 GLN D CA  1 -0.103 0.475  0.016  
ATOM   12169 C  C   . GLN D 1 368 ? -11.483 51.948  4.802   1    126.57 ? 357 GLN D C   1 -0.105 0.476  0.012  
ATOM   12170 O  O   . GLN D 1 368 ? -11.711 53.039  4.271   1    127.33 ? 357 GLN D O   1 -0.107 0.486  0.011  
ATOM   12171 C  CB  . GLN D 1 368 ? -9.795  51.559  6.616   1    125.17 ? 357 GLN D CB  1 -0.09  0.472  0.017  
ATOM   12172 C  CG  . GLN D 1 368 ? -8.864  52.664  6.223   1    126.33 ? 357 GLN D CG  1 -0.081 0.483  0.016  
ATOM   12173 C  CD  . GLN D 1 368 ? -7.461  52.441  6.733   1    129.82 ? 357 GLN D CD  1 -0.068 0.481  0.017  
ATOM   12174 O  OE1 . GLN D 1 368 ? -7.258  52.174  7.915   1    133.11 ? 357 GLN D OE1 1 -0.067 0.478  0.02   
ATOM   12175 N  NE2 . GLN D 1 368 ? -6.48   52.541  5.843   1    136.48 ? 357 GLN D NE2 1 -0.059 0.481  0.015  
ATOM   12176 N  N   . PHE D 1 369 ? -11.441 50.818  4.099   1    127.36 ? 358 PHE D N   1 -0.105 0.466  0.01   
ATOM   12177 C  CA  . PHE D 1 369 ? -11.529 50.819  2.644   1    123.86 ? 358 PHE D CA  1 -0.106 0.466  0.007  
ATOM   12178 C  C   . PHE D 1 369 ? -12.956 50.729  2.124   1    118.95 ? 358 PHE D C   1 -0.119 0.465  0.005  
ATOM   12179 O  O   . PHE D 1 369 ? -13.145 50.752  0.912   1    123.01 ? 358 PHE D O   1 -0.12  0.465  0.002  
ATOM   12180 C  CB  . PHE D 1 369 ? -10.694 49.674  2.069   1    123.8  ? 358 PHE D CB  1 -0.098 0.455  0.005  
ATOM   12181 C  CG  . PHE D 1 369 ? -9.272  49.696  2.528   1    128.87 ? 358 PHE D CG  1 -0.085 0.455  0.006  
ATOM   12182 C  CD1 . PHE D 1 369 ? -8.338  50.491  1.883   1    125.4  ? 358 PHE D CD1 1 -0.076 0.463  0.005  
ATOM   12183 C  CD2 . PHE D 1 369 ? -8.873  48.948  3.634   1    131.21 ? 358 PHE D CD2 1 -0.081 0.449  0.009  
ATOM   12184 C  CE1 . PHE D 1 369 ? -7.026  50.526  2.322   1    129.19 ? 358 PHE D CE1 1 -0.064 0.463  0.006  
ATOM   12185 C  CE2 . PHE D 1 369 ? -7.564  48.978  4.08    1    128.97 ? 358 PHE D CE2 1 -0.069 0.449  0.01   
ATOM   12186 C  CZ  . PHE D 1 369 ? -6.637  49.769  3.422   1    128.69 ? 358 PHE D CZ  1 -0.061 0.456  0.009  
ATOM   12187 N  N   . ARG D 1 370 ? -13.956 50.639  2.989   1    117.11 ? 359 ARG D N   1 -0.128 0.464  0.007  
ATOM   12188 C  CA  . ARG D 1 370 ? -15.354 50.648  2.577   1    113.35 ? 359 ARG D CA  1 -0.141 0.464  0.006  
ATOM   12189 C  C   . ARG D 1 370 ? -16.072 51.849  3.198   1    109.4  ? 359 ARG D C   1 -0.147 0.475  0.008  
ATOM   12190 O  O   . ARG D 1 370 ? -15.449 52.744  3.777   1    110.22 ? 359 ARG D O   1 -0.142 0.483  0.009  
ATOM   12191 C  CB  . ARG D 1 370 ? -16.035 49.336  2.957   1    116.72 ? 359 ARG D CB  1 -0.147 0.452  0.007  
ATOM   12192 C  CG  . ARG D 1 370 ? -15.582 48.139  2.142   1    120.75 ? 359 ARG D CG  1 -0.143 0.441  0.005  
ATOM   12193 C  CD  . ARG D 1 370 ? -15.946 48.281  0.679   1    104.97 ? 359 ARG D CD  1 -0.146 0.442  0.002  
ATOM   12194 N  NE  . ARG D 1 370 ? -14.746 48.489  -0.12   1    118.99 ? 359 ARG D NE  1 -0.135 0.444  -0.0   
ATOM   12195 C  CZ  . ARG D 1 370 ? -13.854 47.545  -0.396  1    119.53 ? 359 ARG D CZ  1 -0.127 0.436  -0.001 
ATOM   12196 N  NH1 . ARG D 1 370 ? -13.999 46.306  0.05    1    126.28 ? 359 ARG D NH1 1 -0.128 0.424  0.0    
ATOM   12197 N  NH2 . ARG D 1 370 ? -12.783 47.854  -1.122  1    110.45 ? 359 ARG D NH2 1 -0.117 0.439  -0.003 
ATOM   12198 N  N   . PHE D 1 371 ? -17.395 51.861  3.062   1    103.88 ? 360 PHE D N   1 -0.159 0.475  0.008  
ATOM   12199 C  CA  . PHE D 1 371 ? -18.257 52.934  3.537   1    106.33 ? 360 PHE D CA  1 -0.167 0.485  0.009  
ATOM   12200 C  C   . PHE D 1 371 ? -19.079 52.443  4.729   1    108.83 ? 360 PHE D C   1 -0.175 0.481  0.012  
ATOM   12201 O  O   . PHE D 1 371 ? -19.126 51.248  5.021   1    112.07 ? 360 PHE D O   1 -0.175 0.47   0.013  
ATOM   12202 C  CB  . PHE D 1 371 ? -19.177 53.428  2.407   1    105.27 ? 360 PHE D CB  1 -0.176 0.49   0.006  
ATOM   12203 C  CG  . PHE D 1 371 ? -18.45  53.89   1.173   1    102.33 ? 360 PHE D CG  1 -0.169 0.494  0.003  
ATOM   12204 C  CD1 . PHE D 1 371 ? -17.359 54.739  1.259   1    102.13 ? 360 PHE D CD1 1 -0.159 0.502  0.003  
ATOM   12205 C  CD2 . PHE D 1 371 ? -18.865 53.456  -0.086  1    113.42 ? 360 PHE D CD2 1 -0.173 0.49   -0.0   
ATOM   12206 C  CE1 . PHE D 1 371 ? -16.689 55.155  0.114   1    111.29 ? 360 PHE D CE1 1 -0.153 0.505  0.0    
ATOM   12207 C  CE2 . PHE D 1 371 ? -18.205 53.863  -1.252  1    108.26 ? 360 PHE D CE2 1 -0.167 0.494  -0.003 
ATOM   12208 C  CZ  . PHE D 1 371 ? -17.112 54.713  -1.152  1    114.26 ? 360 PHE D CZ  1 -0.157 0.501  -0.003 
ATOM   12209 N  N   . ASN D 1 372 ? -19.728 53.375  5.432   1    99.57  ? 361 ASN D N   1 -0.181 0.489  0.014  
ATOM   12210 C  CA  . ASN D 1 372 ? -20.668 53.033  6.494   1    105.53 ? 361 ASN D CA  1 -0.189 0.486  0.016  
ATOM   12211 C  C   . ASN D 1 372 ? -21.938 53.858  6.32    1    105.95 ? 361 ASN D C   1 -0.201 0.494  0.016  
ATOM   12212 O  O   . ASN D 1 372 ? -21.981 54.794  5.515   1    105.13 ? 361 ASN D O   1 -0.201 0.502  0.014  
ATOM   12213 C  CB  . ASN D 1 372 ? -20.065 53.254  7.9     1    107.05 ? 361 ASN D CB  1 -0.184 0.488  0.02   
ATOM   12214 C  CG  . ASN D 1 372 ? -19.789 54.731  8.207   1    102.3  ? 361 ASN D CG  1 -0.181 0.502  0.02   
ATOM   12215 O  OD1 . ASN D 1 372 ? -20.711 55.537  8.32    1    100.75 ? 361 ASN D OD1 1 -0.19  0.509  0.021  
ATOM   12216 N  ND2 . ASN D 1 372 ? -18.512 55.082  8.348   1    100.97 ? 361 ASN D ND2 1 -0.17  0.505  0.021  
ATOM   12217 N  N   . ASP D 1 373 ? -22.973 53.526  7.112   1    104.36 ? 362 ASP D N   1 -0.211 0.491  0.018  
ATOM   12218 C  CA  . ASP D 1 373 ? -24.266 54.203  6.982   1    103.08 ? 362 ASP D CA  1 -0.222 0.497  0.017  
ATOM   12219 C  C   . ASP D 1 373 ? -24.162 55.704  7.192   1    105.77 ? 362 ASP D C   1 -0.221 0.51   0.018  
ATOM   12220 O  O   . ASP D 1 373 ? -25.028 56.444  6.714   1    106.7  ? 362 ASP D O   1 -0.229 0.517  0.017  
ATOM   12221 C  CB  . ASP D 1 373 ? -25.295 53.647  7.967   1    105.77 ? 362 ASP D CB  1 -0.232 0.492  0.02   
ATOM   12222 C  CG  . ASP D 1 373 ? -25.55  52.165  7.782   1    111.34 ? 362 ASP D CG  1 -0.234 0.478  0.019  
ATOM   12223 O  OD1 . ASP D 1 373 ? -24.817 51.543  6.988   1    119.5  ? 362 ASP D OD1 1 -0.227 0.472  0.017  
ATOM   12224 O  OD2 . ASP D 1 373 ? -26.481 51.621  8.428   1    109.82 ? 362 ASP D OD2 1 -0.243 0.473  0.021  
ATOM   12225 N  N   . GLY D 1 374 ? -23.134 56.17   7.901   1    107.71 ? 363 GLY D N   1 -0.212 0.515  0.02   
ATOM   12226 C  CA  . GLY D 1 374 ? -22.947 57.604  8.05    1    109.04 ? 363 GLY D CA  1 -0.21  0.528  0.02   
ATOM   12227 C  C   . GLY D 1 374 ? -22.523 58.269  6.752   1    107.69 ? 363 GLY D C   1 -0.206 0.534  0.017  
ATOM   12228 O  O   . GLY D 1 374 ? -23.065 59.313  6.376   1    108.51 ? 363 GLY D O   1 -0.211 0.544  0.016  
ATOM   12229 N  N   . ASP D 1 375 ? -21.541 57.681  6.056   1    104.97 ? 364 ASP D N   1 -0.197 0.529  0.015  
ATOM   12230 C  CA  . ASP D 1 375 ? -21.121 58.224  4.763   1    112.06 ? 364 ASP D CA  1 -0.194 0.534  0.012  
ATOM   12231 C  C   . ASP D 1 375 ? -22.308 58.349  3.815   1    111.12 ? 364 ASP D C   1 -0.204 0.535  0.01   
ATOM   12232 O  O   . ASP D 1 375 ? -22.67  59.451  3.378   1    111.08 ? 364 ASP D O   1 -0.208 0.545  0.008  
ATOM   12233 C  CB  . ASP D 1 375 ? -20.067 57.333  4.092   1    110.11 ? 364 ASP D CB  1 -0.184 0.525  0.01   
ATOM   12234 C  CG  . ASP D 1 375 ? -18.986 56.856  5.023   1    107.61 ? 364 ASP D CG  1 -0.174 0.521  0.013  
ATOM   12235 O  OD1 . ASP D 1 375 ? -18.077 57.656  5.319   1    111.04 ? 364 ASP D OD1 1 -0.166 0.528  0.013  
ATOM   12236 O  OD2 . ASP D 1 375 ? -19.042 55.674  5.437   1    107.43 ? 364 ASP D OD2 1 -0.175 0.51   0.014  
ATOM   12237 N  N   . LEU D 1 376 ? -22.911 57.209  3.473   1    107.43 ? 365 LEU D N   1 -0.21  0.524  0.009  
ATOM   12238 C  CA  . LEU D 1 376 ? -24.016 57.19   2.525   1    104.21 ? 365 LEU D CA  1 -0.22  0.524  0.006  
ATOM   12239 C  C   . LEU D 1 376 ? -25.138 58.117  2.955   1    108.36 ? 365 LEU D C   1 -0.23  0.533  0.007  
ATOM   12240 O  O   . LEU D 1 376 ? -25.756 58.774  2.11    1    109.25 ? 365 LEU D O   1 -0.236 0.539  0.005  
ATOM   12241 C  CB  . LEU D 1 376 ? -24.549 55.774  2.378   1    99.02  ? 365 LEU D CB  1 -0.225 0.511  0.006  
ATOM   12242 C  CG  . LEU D 1 376 ? -24.048 54.916  1.229   1    104.83 ? 365 LEU D CG  1 -0.22  0.503  0.003  
ATOM   12243 C  CD1 . LEU D 1 376 ? -22.538 54.61   1.325   1    96.72  ? 365 LEU D CD1 1 -0.207 0.5    0.003  
ATOM   12244 C  CD2 . LEU D 1 376 ? -24.903 53.67   1.255   1    102.52 ? 365 LEU D CD2 1 -0.228 0.492  0.003  
ATOM   12245 N  N   . GLY D 1 377 ? -25.44  58.157  4.261   1    109.03 ? 366 GLY D N   1 -0.233 0.533  0.011  
ATOM   12246 C  CA  . GLY D 1 377 ? -26.408 59.098  4.791   1    101.24 ? 366 GLY D CA  1 -0.242 0.542  0.012  
ATOM   12247 C  C   . GLY D 1 377 ? -26.036 60.504  4.371   1    106.95 ? 366 GLY D C   1 -0.239 0.554  0.011  
ATOM   12248 O  O   . GLY D 1 377 ? -26.812 61.199  3.704   1    106.37 ? 366 GLY D O   1 -0.246 0.561  0.009  
ATOM   12249 N  N   . TYR D 1 378 ? -24.813 60.911  4.717   1    109.13 ? 367 TYR D N   1 -0.227 0.558  0.012  
ATOM   12250 C  CA  . TYR D 1 378 ? -24.36  62.258  4.393   1    109.88 ? 367 TYR D CA  1 -0.223 0.571  0.011  
ATOM   12251 C  C   . TYR D 1 378 ? -24.299 62.469  2.89    1    111.44 ? 367 TYR D C   1 -0.223 0.572  0.007  
ATOM   12252 O  O   . TYR D 1 378 ? -24.58  63.565  2.394   1    112.74 ? 367 TYR D O   1 -0.225 0.583  0.006  
ATOM   12253 C  CB  . TYR D 1 378 ? -22.996 62.515  5.023   1    110.9  ? 367 TYR D CB  1 -0.211 0.573  0.013  
ATOM   12254 C  CG  . TYR D 1 378 ? -22.572 63.946  4.906   1    111.96 ? 367 TYR D CG  1 -0.207 0.586  0.012  
ATOM   12255 C  CD1 . TYR D 1 378 ? -23.219 64.937  5.632   1    111.55 ? 367 TYR D CD1 1 -0.213 0.595  0.014  
ATOM   12256 C  CD2 . TYR D 1 378 ? -21.533 64.311  4.066   1    111.51 ? 367 TYR D CD2 1 -0.197 0.589  0.01   
ATOM   12257 C  CE1 . TYR D 1 378 ? -22.84  66.264  5.527   1    117.18 ? 367 TYR D CE1 1 -0.209 0.607  0.014  
ATOM   12258 C  CE2 . TYR D 1 378 ? -21.145 65.635  3.95    1    118.2  ? 367 TYR D CE2 1 -0.194 0.601  0.01   
ATOM   12259 C  CZ  . TYR D 1 378 ? -21.801 66.609  4.681   1    121.83 ? 367 TYR D CZ  1 -0.2   0.61   0.012  
ATOM   12260 O  OH  . TYR D 1 378 ? -21.408 67.927  4.562   1    126.35 ? 367 TYR D OH  1 -0.196 0.622  0.011  
ATOM   12261 N  N   . PHE D 1 379 ? -23.938 61.422  2.151   1    113.04 ? 368 PHE D N   1 -0.219 0.563  0.005  
ATOM   12262 C  CA  . PHE D 1 379 ? -23.863 61.507  0.698   1    108.75 ? 368 PHE D CA  1 -0.219 0.564  0.002  
ATOM   12263 C  C   . PHE D 1 379 ? -25.217 61.884  0.105   1    110.37 ? 368 PHE D C   1 -0.231 0.567  0.0    
ATOM   12264 O  O   . PHE D 1 379 ? -25.366 62.951  -0.505  1    113.37 ? 368 PHE D O   1 -0.232 0.577  -0.001 
ATOM   12265 C  CB  . PHE D 1 379 ? -23.355 60.17   0.157   1    109.61 ? 368 PHE D CB  1 -0.214 0.551  0.0    
ATOM   12266 C  CG  . PHE D 1 379 ? -23.172 60.128  -1.34   1    117.84 ? 368 PHE D CG  1 -0.212 0.551  -0.003 
ATOM   12267 C  CD1 . PHE D 1 379 ? -22.148 60.834  -1.955  1    113.03 ? 368 PHE D CD1 1 -0.203 0.557  -0.005 
ATOM   12268 C  CD2 . PHE D 1 379 ? -24     59.329  -2.121  1    111.72 ? 368 PHE D CD2 1 -0.22  0.544  -0.005 
ATOM   12269 C  CE1 . PHE D 1 379 ? -21.981 60.771  -3.309  1    109.88 ? 368 PHE D CE1 1 -0.201 0.557  -0.008 
ATOM   12270 C  CE2 . PHE D 1 379 ? -23.832 59.26   -3.471  1    113.12 ? 368 PHE D CE2 1 -0.218 0.543  -0.009 
ATOM   12271 C  CZ  . PHE D 1 379 ? -22.822 59.98   -4.071  1    116.86 ? 368 PHE D CZ  1 -0.209 0.55   -0.01  
ATOM   12272 N  N   . TYR D 1 380 ? -26.229 61.036  0.312   1    105.92 ? 369 TYR D N   1 -0.24  0.559  0.001  
ATOM   12273 C  CA  . TYR D 1 380 ? -27.544 61.282  -0.272  1    104.89 ? 369 TYR D CA  1 -0.252 0.562  -0.001 
ATOM   12274 C  C   . TYR D 1 380 ? -28.172 62.558  0.27    1    109.88 ? 369 TYR D C   1 -0.258 0.573  0.001  
ATOM   12275 O  O   . TYR D 1 380 ? -28.853 63.281  -0.469  1    107.01 ? 369 TYR D O   1 -0.264 0.58   -0.001 
ATOM   12276 C  CB  . TYR D 1 380 ? -28.449 60.078  -0.03   1    102.84 ? 369 TYR D CB  1 -0.261 0.551  -0.0   
ATOM   12277 C  CG  . TYR D 1 380 ? -28.008 58.911  -0.861  1    109.18 ? 369 TYR D CG  1 -0.257 0.54   -0.002 
ATOM   12278 C  CD1 . TYR D 1 380 ? -28.067 58.99   -2.247  1    113.67 ? 369 TYR D CD1 1 -0.257 0.541  -0.006 
ATOM   12279 C  CD2 . TYR D 1 380 ? -27.496 57.749  -0.281  1    105.11 ? 369 TYR D CD2 1 -0.252 0.529  -0.001 
ATOM   12280 C  CE1 . TYR D 1 380 ? -27.651 57.951  -3.045  1    113.25 ? 369 TYR D CE1 1 -0.253 0.531  -0.008 
ATOM   12281 C  CE2 . TYR D 1 380 ? -27.074 56.687  -1.069  1    109.46 ? 369 TYR D CE2 1 -0.248 0.519  -0.003 
ATOM   12282 C  CZ  . TYR D 1 380 ? -27.155 56.806  -2.463  1    116.64 ? 369 TYR D CZ  1 -0.249 0.521  -0.006 
ATOM   12283 O  OH  . TYR D 1 380 ? -26.754 55.801  -3.311  1    115.01 ? 369 TYR D OH  1 -0.245 0.511  -0.008 
ATOM   12284 N  N   . GLU D 1 381 ? -27.961 62.853  1.558   1    110.66 ? 370 GLU D N   1 -0.256 0.576  0.004  
ATOM   12285 C  CA  . GLU D 1 381 ? -28.431 64.123  2.1     1    108.4  ? 370 GLU D CA  1 -0.261 0.588  0.005  
ATOM   12286 C  C   . GLU D 1 381 ? -27.747 65.288  1.398   1    110.26 ? 370 GLU D C   1 -0.254 0.598  0.003  
ATOM   12287 O  O   . GLU D 1 381 ? -28.408 66.229  0.939   1    108.77 ? 370 GLU D O   1 -0.26  0.607  0.002  
ATOM   12288 C  CB  . GLU D 1 381 ? -28.184 64.184  3.607   1    114.24 ? 370 GLU D CB  1 -0.258 0.588  0.009  
ATOM   12289 C  CG  . GLU D 1 381 ? -29.451 64.195  4.474   1    114.86 ? 370 GLU D CG  1 -0.27  0.588  0.011  
ATOM   12290 C  CD  . GLU D 1 381 ? -30.283 65.447  4.275   1    114.08 ? 370 GLU D CD  1 -0.278 0.6    0.011  
ATOM   12291 O  OE1 . GLU D 1 381 ? -29.689 66.521  4.012   1    113.37 ? 370 GLU D OE1 1 -0.272 0.61   0.01   
ATOM   12292 O  OE2 . GLU D 1 381 ? -31.531 65.351  4.382   1    114.49 ? 370 GLU D OE2 1 -0.289 0.599  0.011  
ATOM   12293 N  N   . SER D 1 382 ? -26.417 65.226  1.285   1    109.18 ? 371 SER D N   1 -0.242 0.598  0.003  
ATOM   12294 C  CA  . SER D 1 382 ? -25.667 66.285  0.617   1    109.73 ? 371 SER D CA  1 -0.235 0.607  0.002  
ATOM   12295 C  C   . SER D 1 382 ? -26.169 66.485  -0.8    1    112.1  ? 371 SER D C   1 -0.24  0.609  -0.002 
ATOM   12296 O  O   . SER D 1 382 ? -26.566 67.591  -1.182  1    115.47 ? 371 SER D O   1 -0.243 0.619  -0.003 
ATOM   12297 C  CB  . SER D 1 382 ? -24.174 65.957  0.6     1    111.36 ? 371 SER D CB  1 -0.222 0.604  0.001  
ATOM   12298 O  OG  . SER D 1 382 ? -23.689 65.628  1.895   1    112.31 ? 371 SER D OG  1 -0.217 0.601  0.005  
ATOM   12299 N  N   . ILE D 1 383 ? -26.181 65.4    -1.584  1    115.3  ? 372 ILE D N   1 -0.24  0.599  -0.004 
ATOM   12300 C  CA  . ILE D 1 383 ? -26.53  65.462  -3.007  1    111.68 ? 372 ILE D CA  1 -0.243 0.6    -0.008 
ATOM   12301 C  C   . ILE D 1 383 ? -27.863 66.17   -3.207  1    110.96 ? 372 ILE D C   1 -0.255 0.606  -0.008 
ATOM   12302 O  O   . ILE D 1 383 ? -27.955 67.168  -3.931  1    114.3  ? 372 ILE D O   1 -0.256 0.616  -0.01  
ATOM   12303 C  CB  . ILE D 1 383 ? -26.556 64.047  -3.609  1    109.01 ? 372 ILE D CB  1 -0.243 0.587  -0.009 
ATOM   12304 C  CG1 . ILE D 1 383 ? -25.128 63.537  -3.811  1    107.82 ? 372 ILE D CG1 1 -0.23  0.582  -0.01  
ATOM   12305 C  CG2 . ILE D 1 383 ? -27.376 64.016  -4.899  1    105.79 ? 372 ILE D CG2 1 -0.251 0.587  -0.012 
ATOM   12306 C  CD1 . ILE D 1 383 ? -25.022 62.428  -4.829  1    111.9  ? 372 ILE D CD1 1 -0.229 0.572  -0.012 
ATOM   12307 N  N   . PHE D 1 384 ? -28.914 65.67   -2.552  1    108.84 ? 373 PHE D N   1 -0.265 0.602  -0.006 
ATOM   12308 C  CA  . PHE D 1 384 ? -30.25  66.214  -2.761  1    108.9  ? 373 PHE D CA  1 -0.277 0.607  -0.007 
ATOM   12309 C  C   . PHE D 1 384 ? -30.38  67.654  -2.296  1    111.88 ? 373 PHE D C   1 -0.278 0.62   -0.006 
ATOM   12310 O  O   . PHE D 1 384 ? -31.277 68.359  -2.768  1    118.5  ? 373 PHE D O   1 -0.287 0.626  -0.007 
ATOM   12311 C  CB  . PHE D 1 384 ? -31.295 65.354  -2.057  1    110.95 ? 373 PHE D CB  1 -0.287 0.599  -0.005 
ATOM   12312 C  CG  . PHE D 1 384 ? -31.42  63.974  -2.628  1    117.47 ? 373 PHE D CG  1 -0.288 0.586  -0.007 
ATOM   12313 C  CD1 . PHE D 1 384 ? -30.864 63.669  -3.863  1    114.08 ? 373 PHE D CD1 1 -0.283 0.583  -0.01  
ATOM   12314 C  CD2 . PHE D 1 384 ? -32.089 62.975  -1.935  1    117.21 ? 373 PHE D CD2 1 -0.294 0.577  -0.005 
ATOM   12315 C  CE1 . PHE D 1 384 ? -30.971 62.402  -4.396  1    109.05 ? 373 PHE D CE1 1 -0.284 0.572  -0.011 
ATOM   12316 C  CE2 . PHE D 1 384 ? -32.199 61.695  -2.476  1    118.05 ? 373 PHE D CE2 1 -0.295 0.565  -0.006 
ATOM   12317 C  CZ  . PHE D 1 384 ? -31.631 61.416  -3.709  1    107.34 ? 373 PHE D CZ  1 -0.29  0.563  -0.009 
ATOM   12318 N  N   . THR D 1 385 ? -29.524 68.109  -1.382  1    110.87 ? 374 THR D N   1 -0.271 0.624  -0.003 
ATOM   12319 C  CA  . THR D 1 385 ? -29.529 69.527  -1.039  1    114.32 ? 374 THR D CA  1 -0.271 0.637  -0.003 
ATOM   12320 C  C   . THR D 1 385 ? -29.009 70.348  -2.207  1    111.41 ? 374 THR D C   1 -0.266 0.645  -0.006 
ATOM   12321 O  O   . THR D 1 385 ? -29.637 71.33   -2.62   1    114.27 ? 374 THR D O   1 -0.272 0.654  -0.007 
ATOM   12322 C  CB  . THR D 1 385 ? -28.701 69.78   0.225   1    110.48 ? 374 THR D CB  1 -0.263 0.639  0.001  
ATOM   12323 O  OG1 . THR D 1 385 ? -29.396 69.256  1.365   1    105.82 ? 374 THR D OG1 1 -0.269 0.635  0.003  
ATOM   12324 C  CG2 . THR D 1 385 ? -28.439 71.273  0.405   1    101.52 ? 374 THR D CG2 1 -0.261 0.653  0.001  
ATOM   12325 N  N   . LEU D 1 386 ? -27.879 69.929  -2.783  1    111.97 ? 375 LEU D N   1 -0.255 0.641  -0.007 
ATOM   12326 C  CA  . LEU D 1 386 ? -27.416 70.525  -4.036  1    117.69 ? 375 LEU D CA  1 -0.251 0.646  -0.01  
ATOM   12327 C  C   . LEU D 1 386 ? -28.519 70.513  -5.095  1    114.38 ? 375 LEU D C   1 -0.261 0.646  -0.013 
ATOM   12328 O  O   . LEU D 1 386 ? -28.709 71.501  -5.818  1    115.46 ? 375 LEU D O   1 -0.263 0.655  -0.015 
ATOM   12329 C  CB  . LEU D 1 386 ? -26.168 69.79   -4.54   1    111.15 ? 375 LEU D CB  1 -0.24  0.64   -0.011 
ATOM   12330 C  CG  . LEU D 1 386 ? -24.82  70.148  -3.898  1    102.61 ? 375 LEU D CG  1 -0.227 0.643  -0.01  
ATOM   12331 C  CD1 . LEU D 1 386 ? -24.786 69.759  -2.46   1    122.39 ? 375 LEU D CD1 1 -0.227 0.639  -0.006 
ATOM   12332 C  CD2 . LEU D 1 386 ? -23.664 69.488  -4.599  1    113.25 ? 375 LEU D CD2 1 -0.217 0.637  -0.011 
ATOM   12333 N  N   . TYR D 1 387 ? -29.275 69.413  -5.184  1    106.19 ? 376 TYR D N   1 -0.268 0.636  -0.013 
ATOM   12334 C  CA  . TYR D 1 387 ? -30.372 69.364  -6.143  1    116.1  ? 376 TYR D CA  1 -0.278 0.636  -0.015 
ATOM   12335 C  C   . TYR D 1 387 ? -31.434 70.409  -5.814  1    119.57 ? 376 TYR D C   1 -0.288 0.645  -0.015 
ATOM   12336 O  O   . TYR D 1 387 ? -31.841 71.188  -6.688  1    121.51 ? 376 TYR D O   1 -0.292 0.652  -0.017 
ATOM   12337 C  CB  . TYR D 1 387 ? -30.975 67.955  -6.197  1    113.34 ? 376 TYR D CB  1 -0.284 0.623  -0.015 
ATOM   12338 C  CG  . TYR D 1 387 ? -32.288 67.88   -6.958  1    113.32 ? 376 TYR D CG  1 -0.296 0.622  -0.017 
ATOM   12339 C  CD1 . TYR D 1 387 ? -32.409 68.386  -8.239  1    110.2  ? 376 TYR D CD1 1 -0.297 0.627  -0.021 
ATOM   12340 C  CD2 . TYR D 1 387 ? -33.406 67.306  -6.38   1    118.33 ? 376 TYR D CD2 1 -0.306 0.617  -0.016 
ATOM   12341 C  CE1 . TYR D 1 387 ? -33.623 68.32   -8.925  1    121.51 ? 376 TYR D CE1 1 -0.308 0.626  -0.022 
ATOM   12342 C  CE2 . TYR D 1 387 ? -34.62  67.236  -7.053  1    119.97 ? 376 TYR D CE2 1 -0.317 0.616  -0.018 
ATOM   12343 C  CZ  . TYR D 1 387 ? -34.73  67.741  -8.321  1    123.65 ? 376 TYR D CZ  1 -0.318 0.621  -0.021 
ATOM   12344 O  OH  . TYR D 1 387 ? -35.956 67.642  -8.961  1    120.81 ? 376 TYR D OH  1 -0.33  0.62   -0.022 
ATOM   12345 N  N   . ASN D 1 388 ? -31.876 70.466  -4.554  1    114.32 ? 377 ASN D N   1 -0.292 0.646  -0.011 
ATOM   12346 C  CA  . ASN D 1 388 ? -33.026 71.308  -4.23   1    117.06 ? 377 ASN D CA  1 -0.303 0.653  -0.011 
ATOM   12347 C  C   . ASN D 1 388 ? -32.702 72.797  -4.324  1    120.21 ? 377 ASN D C   1 -0.3   0.667  -0.011 
ATOM   12348 O  O   . ASN D 1 388 ? -33.574 73.588  -4.709  1    118.2  ? 377 ASN D O   1 -0.308 0.674  -0.012 
ATOM   12349 C  CB  . ASN D 1 388 ? -33.563 70.959  -2.845  1    118.01 ? 377 ASN D CB  1 -0.308 0.65   -0.007 
ATOM   12350 C  CG  . ASN D 1 388 ? -34.496 69.755  -2.862  1    116.71 ? 377 ASN D CG  1 -0.316 0.639  -0.007 
ATOM   12351 O  OD1 . ASN D 1 388 ? -35.348 69.62   -3.744  1    108.6  ? 377 ASN D OD1 1 -0.324 0.638  -0.009 
ATOM   12352 N  ND2 . ASN D 1 388 ? -34.345 68.878  -1.871  1    119.39 ? 377 ASN D ND2 1 -0.315 0.631  -0.005 
ATOM   12353 N  N   . GLU D 1 389 ? -31.464 73.194  -3.995  1    119.65 ? 378 GLU D N   1 -0.288 0.671  -0.01  
ATOM   12354 C  CA  . GLU D 1 389 ? -31.056 74.593  -4.148  1    126.31 ? 378 GLU D CA  1 -0.285 0.684  -0.01  
ATOM   12355 C  C   . GLU D 1 389 ? -30.92  74.99   -5.624  1    120.31 ? 378 GLU D C   1 -0.283 0.687  -0.014 
ATOM   12356 O  O   . GLU D 1 389 ? -31.398 76.054  -6.042  1    112.82 ? 378 GLU D O   1 -0.288 0.697  -0.015 
ATOM   12357 C  CB  . GLU D 1 389 ? -29.733 74.853  -3.412  1    123.74 ? 378 GLU D CB  1 -0.272 0.686  -0.009 
ATOM   12358 C  CG  . GLU D 1 389 ? -29.589 74.25   -2.011  1    123.98 ? 378 GLU D CG  1 -0.271 0.68   -0.005 
ATOM   12359 C  CD  . GLU D 1 389 ? -30.333 75.015  -0.92   1    137.75 ? 378 GLU D CD  1 -0.278 0.687  -0.002 
ATOM   12360 O  OE1 . GLU D 1 389 ? -31.255 75.799  -1.253  1    142.89 ? 378 GLU D OE1 1 -0.286 0.695  -0.003 
ATOM   12361 O  OE2 . GLU D 1 389 ? -29.991 74.824  0.273   1    126.17 ? 378 GLU D OE2 1 -0.275 0.686  0.001  
ATOM   12362 N  N   . ASN D 1 390 ? -30.255 74.164  -6.423  1    117.97 ? 379 ASN D N   1 -0.277 0.68   -0.016 
ATOM   12363 C  CA  . ASN D 1 390 ? -30.013 74.506  -7.829  1    130.66 ? 379 ASN D CA  1 -0.275 0.683  -0.02  
ATOM   12364 C  C   . ASN D 1 390 ? -30.995 73.809  -8.769  1    126.26 ? 379 ASN D C   1 -0.284 0.676  -0.022 
ATOM   12365 O  O   . ASN D 1 390 ? -30.586 73.209  -9.763  1    125.32 ? 379 ASN D O   1 -0.28  0.671  -0.024 
ATOM   12366 C  CB  . ASN D 1 390 ? -28.57  74.181  -8.21   1    130    ? 379 ASN D CB  1 -0.262 0.68   -0.02  
ATOM   12367 C  CG  . ASN D 1 390 ? -27.553 74.87   -7.311  1    128.65 ? 379 ASN D CG  1 -0.252 0.686  -0.018 
ATOM   12368 O  OD1 . ASN D 1 390 ? -26.977 75.9    -7.675  1    131.44 ? 379 ASN D OD1 1 -0.247 0.696  -0.019 
ATOM   12369 N  ND2 . ASN D 1 390 ? -27.328 74.301  -6.133  1    118.46 ? 379 ASN D ND2 1 -0.25  0.681  -0.015 
ATOM   12370 N  N   . LYS D 1 391 ? -32.302 73.871  -8.486  1    123.85 ? 380 LYS D N   1 -0.296 0.677  -0.021 
ATOM   12371 C  CA  . LYS D 1 391 ? -33.267 73.272  -9.403  1    123.35 ? 380 LYS D CA  1 -0.305 0.671  -0.023 
ATOM   12372 C  C   . LYS D 1 391 ? -33.419 74.086  -10.68  1    132.91 ? 380 LYS D C   1 -0.306 0.679  -0.027 
ATOM   12373 O  O   . LYS D 1 391 ? -33.868 73.547  -11.698 1    130.29 ? 380 LYS D O   1 -0.31  0.674  -0.029 
ATOM   12374 C  CB  . LYS D 1 391 ? -34.625 73.101  -8.725  1    115.57 ? 380 LYS D CB  1 -0.317 0.67   -0.022 
ATOM   12375 C  CG  . LYS D 1 391 ? -34.858 71.697  -8.174  1    118.65 ? 380 LYS D CG  1 -0.319 0.657  -0.02  
ATOM   12376 C  CD  . LYS D 1 391 ? -36.262 71.558  -7.627  1    118.47 ? 380 LYS D CD  1 -0.332 0.656  -0.019 
ATOM   12377 C  CE  . LYS D 1 391 ? -36.45  72.526  -6.458  1    135.83 ? 380 LYS D CE  1 -0.334 0.665  -0.016 
ATOM   12378 N  NZ  . LYS D 1 391 ? -37.84  72.569  -5.921  1    141.95 ? 380 LYS D NZ  1 -0.347 0.665  -0.015 
ATOM   12379 N  N   . ASP D 1 392 ? -33.055 75.371  -10.644 1    137.9  ? 381 ASP D N   1 -0.303 0.691  -0.027 
ATOM   12380 C  CA  . ASP D 1 392 ? -32.949 76.148  -11.874 1    135.45 ? 381 ASP D CA  1 -0.302 0.698  -0.03  
ATOM   12381 C  C   . ASP D 1 392 ? -31.835 75.622  -12.775 1    134.65 ? 381 ASP D C   1 -0.292 0.693  -0.032 
ATOM   12382 O  O   . ASP D 1 392 ? -31.97  75.664  -14.005 1    141.74 ? 381 ASP D O   1 -0.293 0.693  -0.035 
ATOM   12383 C  CB  . ASP D 1 392 ? -32.729 77.631  -11.546 1    142.53 ? 381 ASP D CB  1 -0.3   0.711  -0.029 
ATOM   12384 C  CG  . ASP D 1 392 ? -31.708 77.851  -10.426 1    139.13 ? 381 ASP D CG  1 -0.291 0.713  -0.026 
ATOM   12385 O  OD1 . ASP D 1 392 ? -30.486 77.795  -10.716 1    138.14 ? 381 ASP D OD1 1 -0.279 0.713  -0.027 
ATOM   12386 O  OD2 . ASP D 1 392 ? -32.133 78.084  -9.265  1    131.41 ? 381 ASP D OD2 1 -0.294 0.716  -0.023 
ATOM   12387 N  N   . CYS D 1 393 ? -30.745 75.108  -12.199 1    132.31 ? 382 CYS D N   1 -0.282 0.688  -0.03  
ATOM   12388 C  CA  . CYS D 1 393 ? -29.635 74.575  -12.987 1    134.72 ? 382 CYS D CA  1 -0.272 0.683  -0.032 
ATOM   12389 C  C   . CYS D 1 393 ? -29.665 73.053  -13.135 1    135.06 ? 382 CYS D C   1 -0.272 0.669  -0.033 
ATOM   12390 O  O   . CYS D 1 393 ? -29.544 72.544  -14.255 1    135.95 ? 382 CYS D O   1 -0.271 0.665  -0.036 
ATOM   12391 C  CB  . CYS D 1 393 ? -28.287 74.998  -12.386 1    131.33 ? 382 CYS D CB  1 -0.259 0.687  -0.031 
ATOM   12392 S  SG  . CYS D 1 393 ? -26.886 74.004  -13.028 1    124.46 ? 382 CYS D SG  1 -0.246 0.678  -0.033 
ATOM   12393 N  N   . VAL D 1 394 ? -29.808 72.302  -12.04  1    134.65 ? 383 VAL D N   1 -0.273 0.663  -0.03  
ATOM   12394 C  CA  . VAL D 1 394 ? -29.798 70.842  -12.13  1    131.52 ? 383 VAL D CA  1 -0.273 0.649  -0.03  
ATOM   12395 C  C   . VAL D 1 394 ? -31.132 70.359  -12.674 1    132.33 ? 383 VAL D C   1 -0.285 0.645  -0.032 
ATOM   12396 O  O   . VAL D 1 394 ? -32.2   70.644  -12.11  1    128.35 ? 383 VAL D O   1 -0.295 0.647  -0.03  
ATOM   12397 C  CB  . VAL D 1 394 ? -29.493 70.204  -10.767 1    128.74 ? 383 VAL D CB  1 -0.27  0.643  -0.027 
ATOM   12398 C  CG1 . VAL D 1 394 ? -30.031 68.78   -10.739 1    127.61 ? 383 VAL D CG1 1 -0.275 0.63   -0.027 
ATOM   12399 C  CG2 . VAL D 1 394 ? -27.992 70.202  -10.509 1    127.8  ? 383 VAL D CG2 1 -0.257 0.643  -0.026 
ATOM   12400 N  N   . ASP D 1 395 ? -31.071 69.6    -13.766 1    128.73 ? 384 ASP D N   1 -0.285 0.638  -0.034 
ATOM   12401 C  CA  . ASP D 1 395 ? -32.245 69.231  -14.539 1    129.9  ? 384 ASP D CA  1 -0.295 0.634  -0.036 
ATOM   12402 C  C   . ASP D 1 395 ? -32.805 67.868  -14.153 1    124.93 ? 384 ASP D C   1 -0.301 0.622  -0.035 
ATOM   12403 O  O   . ASP D 1 395 ? -34.011 67.736  -13.903 1    117.26 ? 384 ASP D O   1 -0.312 0.621  -0.035 
ATOM   12404 C  CB  . ASP D 1 395 ? -31.889 69.268  -16.035 1    129.28 ? 384 ASP D CB  1 -0.292 0.635  -0.04  
ATOM   12405 C  CG  . ASP D 1 395 ? -33.114 69.365  -16.934 1    134.19 ? 384 ASP D CG  1 -0.303 0.636  -0.042 
ATOM   12406 O  OD1 . ASP D 1 395 ? -34.044 70.129  -16.585 1    132.19 ? 384 ASP D OD1 1 -0.312 0.643  -0.041 
ATOM   12407 O  OD2 . ASP D 1 395 ? -33.138 68.696  -17.997 1    136.61 ? 384 ASP D OD2 1 -0.304 0.63   -0.045 
ATOM   12408 N  N   . THR D 1 396 ? -31.953 66.841  -14.109 1    122.62 ? 385 THR D N   1 -0.293 0.613  -0.035 
ATOM   12409 C  CA  . THR D 1 396 ? -32.393 65.455  -13.999 1    117.78 ? 385 THR D CA  1 -0.297 0.6    -0.035 
ATOM   12410 C  C   . THR D 1 396 ? -31.447 64.693  -13.09  1    111.95 ? 385 THR D C   1 -0.288 0.593  -0.033 
ATOM   12411 O  O   . THR D 1 396 ? -30.24  64.949  -13.072 1    108.5  ? 385 THR D O   1 -0.277 0.595  -0.033 
ATOM   12412 C  CB  . THR D 1 396 ? -32.451 64.728  -15.376 1    123.77 ? 385 THR D CB  1 -0.297 0.593  -0.038 
ATOM   12413 O  OG1 . THR D 1 396 ? -31.128 64.38   -15.822 1    125.35 ? 385 THR D OG1 1 -0.285 0.59   -0.04  
ATOM   12414 C  CG2 . THR D 1 396 ? -33.104 65.584  -16.434 1    120.7  ? 385 THR D CG2 1 -0.303 0.601  -0.041 
ATOM   12415 N  N   . ILE D 1 397 ? -32.012 63.741  -12.347 1    117.08 ? 386 ILE D N   1 -0.293 0.584  -0.031 
ATOM   12416 C  CA  . ILE D 1 397 ? -31.261 62.831  -11.475 1    114.91 ? 386 ILE D CA  1 -0.286 0.576  -0.029 
ATOM   12417 C  C   . ILE D 1 397 ? -31.811 61.423  -11.695 1    109.77 ? 386 ILE D C   1 -0.292 0.563  -0.029 
ATOM   12418 O  O   . ILE D 1 397 ? -32.953 61.13   -11.312 1    109.91 ? 386 ILE D O   1 -0.302 0.56   -0.028 
ATOM   12419 C  CB  . ILE D 1 397 ? -31.336 63.244  -9.995  1    109.14 ? 386 ILE D CB  1 -0.287 0.58   -0.025 
ATOM   12420 C  CG1 . ILE D 1 397 ? -30.25  64.272  -9.687  1    108.15 ? 386 ILE D CG1 1 -0.277 0.589  -0.024 
ATOM   12421 C  CG2 . ILE D 1 397 ? -31.165 62.052  -9.054  1    106.98 ? 386 ILE D CG2 1 -0.286 0.569  -0.023 
ATOM   12422 C  CD1 . ILE D 1 397 ? -30.335 64.835  -8.288  1    114.78 ? 386 ILE D CD1 1 -0.278 0.594  -0.021 
ATOM   12423 N  N   . TYR D 1 398 ? -31.024 60.572  -12.35  1    99.17  ? 387 TYR D N   1 -0.284 0.555  -0.031 
ATOM   12424 C  CA  . TYR D 1 398 ? -31.335 59.159  -12.482 1    101.12 ? 387 TYR D CA  1 -0.287 0.542  -0.031 
ATOM   12425 C  C   . TYR D 1 398 ? -30.383 58.369  -11.607 1    100.13 ? 387 TYR D C   1 -0.278 0.535  -0.029 
ATOM   12426 O  O   . TYR D 1 398 ? -29.174 58.627  -11.593 1    98.07  ? 387 TYR D O   1 -0.267 0.537  -0.029 
ATOM   12427 C  CB  . TYR D 1 398 ? -31.22  58.648  -13.933 1    110.28 ? 387 TYR D CB  1 -0.286 0.537  -0.035 
ATOM   12428 C  CG  . TYR D 1 398 ? -31.174 57.124  -14.03  1    100.26 ? 387 TYR D CG  1 -0.286 0.523  -0.035 
ATOM   12429 C  CD1 . TYR D 1 398 ? -32.348 56.372  -14.033 1    97.46  ? 387 TYR D CD1 1 -0.296 0.517  -0.035 
ATOM   12430 C  CD2 . TYR D 1 398 ? -29.956 56.438  -14.079 1    96.04  ? 387 TYR D CD2 1 -0.275 0.517  -0.035 
ATOM   12431 C  CE1 . TYR D 1 398 ? -32.314 54.981  -14.096 1    96.1   ? 387 TYR D CE1 1 -0.296 0.504  -0.035 
ATOM   12432 C  CE2 . TYR D 1 398 ? -29.91  55.045  -14.131 1    93.41  ? 387 TYR D CE2 1 -0.274 0.504  -0.035 
ATOM   12433 C  CZ  . TYR D 1 398 ? -31.093 54.322  -14.15  1    95.37  ? 387 TYR D CZ  1 -0.285 0.498  -0.035 
ATOM   12434 O  OH  . TYR D 1 398 ? -31.061 52.941  -14.224 1    96.29  ? 387 TYR D OH  1 -0.285 0.485  -0.036 
ATOM   12435 N  N   . TRP D 1 399 ? -30.939 57.373  -10.926 1    100.19 ? 388 TRP D N   1 -0.284 0.526  -0.027 
ATOM   12436 C  CA  . TRP D 1 399 ? -30.223 56.54   -9.973  1    102.52 ? 388 TRP D CA  1 -0.277 0.518  -0.025 
ATOM   12437 C  C   . TRP D 1 399 ? -30.444 55.08   -10.356 1    102.84 ? 388 TRP D C   1 -0.279 0.505  -0.026 
ATOM   12438 O  O   . TRP D 1 399 ? -31.587 54.654  -10.579 1    100.19 ? 388 TRP D O   1 -0.289 0.501  -0.026 
ATOM   12439 C  CB  . TRP D 1 399 ? -30.725 56.849  -8.552  1    106.05 ? 388 TRP D CB  1 -0.282 0.521  -0.021 
ATOM   12440 C  CG  . TRP D 1 399 ? -30.01  56.191  -7.418  1    104    ? 388 TRP D CG  1 -0.275 0.515  -0.019 
ATOM   12441 C  CD1 . TRP D 1 399 ? -29.004 56.718  -6.659  1    103.07 ? 388 TRP D CD1 1 -0.266 0.52   -0.017 
ATOM   12442 C  CD2 . TRP D 1 399 ? -30.279 54.893  -6.888  1    102.16 ? 388 TRP D CD2 1 -0.277 0.503  -0.017 
ATOM   12443 N  NE1 . TRP D 1 399 ? -28.615 55.814  -5.695  1    103.89 ? 388 TRP D NE1 1 -0.262 0.511  -0.014 
ATOM   12444 C  CE2 . TRP D 1 399 ? -29.385 54.684  -5.81   1    105.54 ? 388 TRP D CE2 1 -0.269 0.501  -0.015 
ATOM   12445 C  CE3 . TRP D 1 399 ? -31.183 53.878  -7.227  1    97.45  ? 388 TRP D CE3 1 -0.286 0.494  -0.018 
ATOM   12446 C  CZ2 . TRP D 1 399 ? -29.373 53.495  -5.057  1    100.01 ? 388 TRP D CZ2 1 -0.269 0.49   -0.013 
ATOM   12447 C  CZ3 . TRP D 1 399 ? -31.183 52.7    -6.475  1    103.21 ? 388 TRP D CZ3 1 -0.286 0.483  -0.016 
ATOM   12448 C  CH2 . TRP D 1 399 ? -30.279 52.519  -5.4    1    96.32  ? 388 TRP D CH2 1 -0.277 0.481  -0.013 
ATOM   12449 N  N   . GLY D 1 400 ? -29.357 54.317  -10.454 1    98.94  ? 389 GLY D N   1 -0.269 0.498  -0.026 
ATOM   12450 C  CA  . GLY D 1 400 ? -29.51  52.947  -10.901 1    98.24  ? 389 GLY D CA  1 -0.27  0.485  -0.027 
ATOM   12451 C  C   . GLY D 1 400 ? -28.981 51.905  -9.939  1    99.69  ? 389 GLY D C   1 -0.266 0.476  -0.025 
ATOM   12452 O  O   . GLY D 1 400 ? -27.784 51.892  -9.636  1    100.41 ? 389 GLY D O   1 -0.255 0.476  -0.024 
ATOM   12453 N  N   . LEU D 1 401 ? -29.876 51.047  -9.444  1    92.07  ? 390 LEU D N   1 -0.274 0.468  -0.024 
ATOM   12454 C  CA  . LEU D 1 401 ? -29.473 49.884  -8.661  1    92.16  ? 390 LEU D CA  1 -0.27  0.457  -0.022 
ATOM   12455 C  C   . LEU D 1 401 ? -28.424 49.063  -9.414  1    97.55  ? 390 LEU D C   1 -0.26  0.45   -0.024 
ATOM   12456 O  O   . LEU D 1 401 ? -28.729 48.461  -10.45  1    96.42  ? 390 LEU D O   1 -0.263 0.444  -0.026 
ATOM   12457 C  CB  . LEU D 1 401 ? -30.705 49.029  -8.35   1    89.11  ? 390 LEU D CB  1 -0.281 0.449  -0.021 
ATOM   12458 C  CG  . LEU D 1 401 ? -30.528 47.749  -7.524  1    89.56  ? 390 LEU D CG  1 -0.28  0.438  -0.019 
ATOM   12459 C  CD1 . LEU D 1 401 ? -30.243 46.514  -8.399  1    103.89 ? 390 LEU D CD1 1 -0.277 0.426  -0.021 
ATOM   12460 C  CD2 . LEU D 1 401 ? -29.446 47.94   -6.445  1    93.22  ? 390 LEU D CD2 1 -0.27  0.439  -0.016 
ATOM   12461 N  N   . GLU D 1 402 ? -27.202 49.02   -8.891  1    100.5  ? 391 GLU D N   1 -0.249 0.449  -0.022 
ATOM   12462 C  CA  . GLU D 1 402 ? -26.175 48.2    -9.528  1    97.31  ? 391 GLU D CA  1 -0.24  0.442  -0.024 
ATOM   12463 C  C   . GLU D 1 402 ? -25.869 46.94   -8.693  1    101.38 ? 391 GLU D C   1 -0.237 0.43   -0.022 
ATOM   12464 O  O   . GLU D 1 402 ? -26.631 45.986  -8.741  1    104.1  ? 391 GLU D O   1 -0.244 0.421  -0.022 
ATOM   12465 C  CB  . GLU D 1 402 ? -24.886 48.986  -9.743  1    96.64  ? 391 GLU D CB  1 -0.228 0.449  -0.024 
ATOM   12466 C  CG  . GLU D 1 402 ? -25.067 50.177  -10.665 1    103.4  ? 391 GLU D CG  1 -0.23  0.46   -0.027 
ATOM   12467 C  CD  . GLU D 1 402 ? -25.314 49.793  -12.13  1    105.71 ? 391 GLU D CD  1 -0.232 0.456  -0.03  
ATOM   12468 O  OE1 . GLU D 1 402 ? -26.404 50.128  -12.663 1    102    ? 391 GLU D OE1 1 -0.242 0.459  -0.032 
ATOM   12469 O  OE2 . GLU D 1 402 ? -24.427 49.164  -12.757 1    102.94 ? 391 GLU D OE2 1 -0.224 0.451  -0.032 
ATOM   12470 N  N   . GLY D 1 403 ? -24.751 46.978  -7.975  1    104.8  ? 392 GLY D N   1 -0.227 0.431  -0.02  
ATOM   12471 C  CA  . GLY D 1 403 ? -24.384 45.891  -7.09   1    106.61 ? 392 GLY D CA  1 -0.223 0.421  -0.018 
ATOM   12472 C  C   . GLY D 1 403 ? -24.817 46.139  -5.65   1    109.55 ? 392 GLY D C   1 -0.227 0.423  -0.014 
ATOM   12473 O  O   . GLY D 1 403 ? -25.474 47.13   -5.322  1    108.59 ? 392 GLY D O   1 -0.233 0.432  -0.013 
ATOM   12474 N  N   . GLY D 1 404 ? -24.418 45.215  -4.767  1    112.24 ? 393 GLY D N   1 -0.224 0.414  -0.012 
ATOM   12475 C  CA  . GLY D 1 404 ? -24.771 45.266  -3.365  1    108.14 ? 393 GLY D CA  1 -0.227 0.415  -0.008 
ATOM   12476 C  C   . GLY D 1 404 ? -25.66  44.099  -3.004  1    107.91 ? 393 GLY D C   1 -0.235 0.404  -0.008 
ATOM   12477 O  O   . GLY D 1 404 ? -26.854 44.126  -3.313  1    105.18 ? 393 GLY D O   1 -0.246 0.404  -0.008 
ATOM   12478 N  N   . TYR D 1 405 ? -25.111 43.065  -2.363  1    107.89 ? 394 TYR D N   1 -0.23  0.395  -0.006 
ATOM   12479 C  CA  . TYR D 1 405 ? -25.704 41.742  -2.495  1    109.07 ? 394 TYR D CA  1 -0.236 0.383  -0.006 
ATOM   12480 C  C   . TYR D 1 405 ? -26.14  41.096  -1.193  1    110.5  ? 394 TYR D C   1 -0.24  0.377  -0.003 
ATOM   12481 O  O   . TYR D 1 405 ? -27.15  40.384  -1.207  1    110.67 ? 394 TYR D O   1 -0.249 0.37   -0.003 
ATOM   12482 C  CB  . TYR D 1 405 ? -24.732 40.807  -3.246  1    108.99 ? 394 TYR D CB  1 -0.227 0.374  -0.008 
ATOM   12483 C  CG  . TYR D 1 405 ? -24.37  41.334  -4.631  1    108.4  ? 394 TYR D CG  1 -0.223 0.379  -0.012 
ATOM   12484 C  CD1 . TYR D 1 405 ? -25.265 41.218  -5.7    1    108.4  ? 394 TYR D CD1 1 -0.232 0.378  -0.014 
ATOM   12485 C  CD2 . TYR D 1 405 ? -23.148 41.958  -4.868  1    106.74 ? 394 TYR D CD2 1 -0.212 0.385  -0.012 
ATOM   12486 C  CE1 . TYR D 1 405 ? -24.953 41.708  -6.976  1    108.32 ? 394 TYR D CE1 1 -0.229 0.382  -0.017 
ATOM   12487 C  CE2 . TYR D 1 405 ? -22.814 42.449  -6.147  1    111.94 ? 394 TYR D CE2 1 -0.209 0.389  -0.015 
ATOM   12488 C  CZ  . TYR D 1 405 ? -23.723 42.326  -7.199  1    116.29 ? 394 TYR D CZ  1 -0.217 0.388  -0.018 
ATOM   12489 O  OH  . TYR D 1 405 ? -23.398 42.818  -8.464  1    112.01 ? 394 TYR D OH  1 -0.214 0.392  -0.021 
ATOM   12490 N  N   . ASP D 1 406 ? -25.433 41.318  -0.077  1    111.07 ? 395 ASP D N   1 -0.233 0.379  -0.0   
ATOM   12491 C  CA  . ASP D 1 406 ? -25.853 40.741  1.201   1    109.07 ? 395 ASP D CA  1 -0.237 0.373  0.003  
ATOM   12492 C  C   . ASP D 1 406 ? -27.161 41.361  1.686   1    105.29 ? 395 ASP D C   1 -0.249 0.379  0.004  
ATOM   12493 O  O   . ASP D 1 406 ? -27.303 42.587  1.699   1    106.23 ? 395 ASP D O   1 -0.25  0.39   0.004  
ATOM   12494 C  CB  . ASP D 1 406 ? -24.787 40.945  2.268   1    113.26 ? 395 ASP D CB  1 -0.227 0.375  0.006  
ATOM   12495 C  CG  . ASP D 1 406 ? -25.301 40.592  3.649   1    111.51 ? 395 ASP D CG  1 -0.232 0.372  0.009  
ATOM   12496 O  OD1 . ASP D 1 406 ? -25.672 39.412  3.838   1    114.66 ? 395 ASP D OD1 1 -0.235 0.361  0.01   
ATOM   12497 O  OD2 . ASP D 1 406 ? -25.359 41.482  4.535   1    113.41 ? 395 ASP D OD2 1 -0.232 0.38   0.011  
ATOM   12498 N  N   . ARG D 1 407 ? -28.096 40.526  2.145   1    102.12 ? 396 ARG D N   1 -0.257 0.371  0.005  
ATOM   12499 C  CA  . ARG D 1 407 ? -29.471 41      2.263   1    98.11  ? 396 ARG D CA  1 -0.27  0.376  0.006  
ATOM   12500 C  C   . ARG D 1 407 ? -29.654 41.971  3.429   1    104.32 ? 396 ARG D C   1 -0.272 0.385  0.009  
ATOM   12501 O  O   . ARG D 1 407 ? -30.082 43.108  3.215   1    105.69 ? 396 ARG D O   1 -0.276 0.395  0.008  
ATOM   12502 C  CB  . ARG D 1 407 ? -30.451 39.841  2.368   1    99.87  ? 396 ARG D CB  1 -0.279 0.365  0.006  
ATOM   12503 C  CG  . ARG D 1 407 ? -31.878 40.328  2.583   1    99.45  ? 396 ARG D CG  1 -0.292 0.37   0.006  
ATOM   12504 C  CD  . ARG D 1 407 ? -32.862 39.189  2.548   1    101.17 ? 396 ARG D CD  1 -0.301 0.359  0.006  
ATOM   12505 N  NE  . ARG D 1 407 ? -34.223 39.633  2.809   1    98.89  ? 396 ARG D NE  1 -0.314 0.363  0.007  
ATOM   12506 C  CZ  . ARG D 1 407 ? -35.295 38.867  2.664   1    104.78 ? 396 ARG D CZ  1 -0.323 0.356  0.007  
ATOM   12507 N  NH1 . ARG D 1 407 ? -35.196 37.597  2.295   1    100.92 ? 396 ARG D NH1 1 -0.323 0.345  0.006  
ATOM   12508 N  NH2 . ARG D 1 407 ? -36.499 39.386  2.882   1    110.03 ? 396 ARG D NH2 1 -0.334 0.361  0.007  
ATOM   12509 N  N   . THR D 1 408 ? -29.354 41.555  4.675   1    106.23 ? 397 THR D N   1 -0.269 0.381  0.012  
ATOM   12510 C  CA  . THR D 1 408 ? -29.583 42.471  5.805   1    105.28 ? 397 THR D CA  1 -0.271 0.389  0.014  
ATOM   12511 C  C   . THR D 1 408 ? -28.849 43.796  5.595   1    99.61  ? 397 THR D C   1 -0.264 0.401  0.014  
ATOM   12512 O  O   . THR D 1 408 ? -29.345 44.854  6.017   1    91.54  ? 397 THR D O   1 -0.269 0.411  0.015  
ATOM   12513 C  CB  . THR D 1 408 ? -29.185 41.858  7.179   1    100.16 ? 397 THR D CB  1 -0.267 0.384  0.018  
ATOM   12514 O  OG1 . THR D 1 408 ? -27.846 41.342  7.157   1    102.99 ? 397 THR D OG1 1 -0.255 0.379  0.018  
ATOM   12515 C  CG2 . THR D 1 408 ? -30.17  40.761  7.632   1    94.25  ? 397 THR D CG2 1 -0.276 0.374  0.019  
ATOM   12516 N  N   . MET D 1 409 ? -27.697 43.755  4.901   1    97.99  ? 398 MET D N   1 -0.254 0.401  0.012  
ATOM   12517 C  CA  . MET D 1 409 ? -26.976 44.976  4.524   1    100.76 ? 398 MET D CA  1 -0.247 0.412  0.011  
ATOM   12518 C  C   . MET D 1 409 ? -27.803 45.854  3.586   1    103.74 ? 398 MET D C   1 -0.255 0.42   0.009  
ATOM   12519 O  O   . MET D 1 409 ? -28.026 47.035  3.861   1    105.19 ? 398 MET D O   1 -0.257 0.431  0.01   
ATOM   12520 C  CB  . MET D 1 409 ? -25.626 44.644  3.875   1    105.74 ? 398 MET D CB  1 -0.235 0.409  0.01   
ATOM   12521 C  CG  . MET D 1 409 ? -24.646 45.843  3.801   1    110.93 ? 398 MET D CG  1 -0.226 0.42   0.009  
ATOM   12522 S  SD  . MET D 1 409 ? -24.987 47.06   2.444   1    99.36  ? 398 MET D SD  1 -0.229 0.431  0.006  
ATOM   12523 C  CE  . MET D 1 409 ? -24.857 45.985  1.005   1    102.11 ? 398 MET D CE  1 -0.228 0.421  0.003  
ATOM   12524 N  N   . TYR D 1 410 ? -28.289 45.301  2.478   1    103.21 ? 399 TYR D N   1 -0.259 0.415  0.006  
ATOM   12525 C  CA  . TYR D 1 410 ? -28.957 46.188  1.533   1    106.64 ? 399 TYR D CA  1 -0.265 0.423  0.004  
ATOM   12526 C  C   . TYR D 1 410 ? -30.376 46.556  1.967   1    101.78 ? 399 TYR D C   1 -0.278 0.427  0.005  
ATOM   12527 O  O   . TYR D 1 410 ? -30.862 47.642  1.613   1    102.24 ? 399 TYR D O   1 -0.283 0.437  0.004  
ATOM   12528 C  CB  . TYR D 1 410 ? -28.927 45.58   0.118   1    97.6   ? 399 TYR D CB  1 -0.265 0.418  0.0    
ATOM   12529 C  CG  . TYR D 1 410 ? -29.723 44.307  -0.162  1    98.15  ? 399 TYR D CG  1 -0.272 0.406  -0.0   
ATOM   12530 C  CD1 . TYR D 1 410 ? -31.1   44.25   0.028   1    94.37  ? 399 TYR D CD1 1 -0.285 0.406  0.0    
ATOM   12531 C  CD2 . TYR D 1 410 ? -29.098 43.186  -0.717  1    103.46 ? 399 TYR D CD2 1 -0.267 0.396  -0.002 
ATOM   12532 C  CE1 . TYR D 1 410 ? -31.834 43.105  -0.266  1    94.25  ? 399 TYR D CE1 1 -0.292 0.395  -0.001 
ATOM   12533 C  CE2 . TYR D 1 410 ? -29.828 42.023  -1.029  1    101.2  ? 399 TYR D CE2 1 -0.273 0.385  -0.003 
ATOM   12534 C  CZ  . TYR D 1 410 ? -31.199 41.992  -0.798  1    99.93  ? 399 TYR D CZ  1 -0.286 0.385  -0.002 
ATOM   12535 O  OH  . TYR D 1 410 ? -31.929 40.853  -1.101  1    95.12  ? 399 TYR D OH  1 -0.293 0.374  -0.003 
ATOM   12536 N  N   . GLU D 1 411 ? -31.065 45.669  2.698   1    97.79  ? 400 GLU D N   1 -0.285 0.419  0.007  
ATOM   12537 C  CA  . GLU D 1 411 ? -32.382 46.028  3.217   1    97.38  ? 400 GLU D CA  1 -0.297 0.422  0.008  
ATOM   12538 C  C   . GLU D 1 411 ? -32.273 47.27   4.082   1    99.43  ? 400 GLU D C   1 -0.296 0.433  0.01   
ATOM   12539 O  O   . GLU D 1 411 ? -33.157 48.135  4.055   1    97.01  ? 400 GLU D O   1 -0.304 0.441  0.01   
ATOM   12540 C  CB  . GLU D 1 411 ? -32.997 44.866  4.008   1    95.95  ? 400 GLU D CB  1 -0.302 0.411  0.01   
ATOM   12541 C  CG  . GLU D 1 411 ? -33.176 43.578  3.214   1    104.65 ? 400 GLU D CG  1 -0.304 0.399  0.008  
ATOM   12542 C  CD  . GLU D 1 411 ? -34.455 42.811  3.56    1    109.68 ? 400 GLU D CD  1 -0.316 0.392  0.009  
ATOM   12543 O  OE1 . GLU D 1 411 ? -34.85  42.804  4.755   1    112.3  ? 400 GLU D OE1 1 -0.319 0.392  0.012  
ATOM   12544 O  OE2 . GLU D 1 411 ? -35.069 42.221  2.631   1    99.56  ? 400 GLU D OE2 1 -0.321 0.387  0.007  
ATOM   12545 N  N   . ARG D 1 412 ? -31.166 47.389  4.825   1    105.8  ? 401 ARG D N   1 -0.286 0.434  0.012  
ATOM   12546 C  CA  . ARG D 1 412 ? -30.927 48.568  5.65    1    102.21 ? 401 ARG D CA  1 -0.283 0.445  0.014  
ATOM   12547 C  C   . ARG D 1 412 ? -30.724 49.803  4.781   1    102.51 ? 401 ARG D C   1 -0.282 0.456  0.012  
ATOM   12548 O  O   . ARG D 1 412 ? -31.414 50.813  4.953   1    100.82 ? 401 ARG D O   1 -0.288 0.466  0.012  
ATOM   12549 C  CB  . ARG D 1 412 ? -29.725 48.329  6.571   1    101.77 ? 401 ARG D CB  1 -0.272 0.443  0.016  
ATOM   12550 C  CG  . ARG D 1 412 ? -29.377 49.497  7.523   1    108.04 ? 401 ARG D CG  1 -0.269 0.454  0.019  
ATOM   12551 C  CD  . ARG D 1 412 ? -28.48  49.056  8.716   1    99.91  ? 401 ARG D CD  1 -0.261 0.45   0.022  
ATOM   12552 N  NE  . ARG D 1 412 ? -27.73  47.83   8.461   1    100.58 ? 401 ARG D NE  1 -0.254 0.438  0.021  
ATOM   12553 C  CZ  . ARG D 1 412 ? -26.445 47.785  8.129   1    105.79 ? 401 ARG D CZ  1 -0.242 0.438  0.02   
ATOM   12554 N  NH1 . ARG D 1 412 ? -25.721 48.889  8.024   1    104.04 ? 401 ARG D NH1 1 -0.236 0.448  0.02   
ATOM   12555 N  NH2 . ARG D 1 412 ? -25.87  46.6    7.902   1    99.75  ? 401 ARG D NH2 1 -0.237 0.427  0.02   
ATOM   12556 N  N   . GLU D 1 413 ? -29.813 49.724  3.805   1    103.11 ? 402 GLU D N   1 -0.273 0.456  0.01   
ATOM   12557 C  CA  . GLU D 1 413 ? -29.501 50.903  3.002   1    101.83 ? 402 GLU D CA  1 -0.27  0.466  0.007  
ATOM   12558 C  C   . GLU D 1 413 ? -30.686 51.365  2.166   1    102.17 ? 402 GLU D C   1 -0.281 0.471  0.005  
ATOM   12559 O  O   . GLU D 1 413 ? -30.865 52.576  1.982   1    101.7  ? 402 GLU D O   1 -0.283 0.482  0.005  
ATOM   12560 C  CB  . GLU D 1 413 ? -28.286 50.625  2.124   1    104.81 ? 402 GLU D CB  1 -0.259 0.464  0.005  
ATOM   12561 C  CG  . GLU D 1 413 ? -27.261 49.744  2.805   1    106.36 ? 402 GLU D CG  1 -0.25  0.456  0.007  
ATOM   12562 C  CD  . GLU D 1 413 ? -26.664 50.361  4.076   1    113.81 ? 402 GLU D CD  1 -0.244 0.462  0.01   
ATOM   12563 O  OE1 . GLU D 1 413 ? -25.648 49.821  4.562   1    115.76 ? 402 GLU D OE1 1 -0.235 0.457  0.011  
ATOM   12564 O  OE2 . GLU D 1 413 ? -27.174 51.38   4.6     1    112.68 ? 402 GLU D OE2 1 -0.249 0.471  0.011  
ATOM   12565 N  N   . LEU D 1 414 ? -31.498 50.434  1.643   1    95.47  ? 403 LEU D N   1 -0.289 0.462  0.004  
ATOM   12566 C  CA  . LEU D 1 414 ? -32.722 50.857  0.973   1    99.34  ? 403 LEU D CA  1 -0.3   0.466  0.002  
ATOM   12567 C  C   . LEU D 1 414 ? -33.596 51.688  1.923   1    99.86  ? 403 LEU D C   1 -0.308 0.474  0.005  
ATOM   12568 O  O   . LEU D 1 414 ? -33.965 52.822  1.599   1    102.77 ? 403 LEU D O   1 -0.311 0.484  0.004  
ATOM   12569 C  CB  . LEU D 1 414 ? -33.484 49.65   0.399   1    95.44  ? 403 LEU D CB  1 -0.307 0.455  0.001  
ATOM   12570 C  CG  . LEU D 1 414 ? -34.801 49.953  -0.338  1    88.45  ? 403 LEU D CG  1 -0.319 0.458  -0.001 
ATOM   12571 C  CD1 . LEU D 1 414 ? -34.52  50.934  -1.505  1    95.16  ? 403 LEU D CD1 1 -0.316 0.467  -0.004 
ATOM   12572 C  CD2 . LEU D 1 414 ? -35.54  48.645  -0.749  1    91.08  ? 403 LEU D CD2 1 -0.326 0.446  -0.002 
ATOM   12573 N  N   . LYS D 1 415 ? -33.89  51.172  3.124   1    100.92 ? 404 LYS D N   1 -0.311 0.469  0.008  
ATOM   12574 C  CA  . LYS D 1 415 ? -34.655 51.977  4.082   1    108.7  ? 404 LYS D CA  1 -0.318 0.476  0.01   
ATOM   12575 C  C   . LYS D 1 415 ? -33.95  53.294  4.384   1    105.53 ? 404 LYS D C   1 -0.311 0.488  0.011  
ATOM   12576 O  O   . LYS D 1 415 ? -34.584 54.355  4.413   1    107.29 ? 404 LYS D O   1 -0.317 0.498  0.011  
ATOM   12577 C  CB  . LYS D 1 415 ? -34.917 51.221  5.393   1    100.85 ? 404 LYS D CB  1 -0.32  0.469  0.013  
ATOM   12578 C  CG  . LYS D 1 415 ? -35.946 51.938  6.286   1    107.63 ? 404 LYS D CG  1 -0.329 0.476  0.016  
ATOM   12579 C  CD  . LYS D 1 415 ? -36.039 51.353  7.712   1    119.56 ? 404 LYS D CD  1 -0.33  0.471  0.019  
ATOM   12580 C  CE  . LYS D 1 415 ? -37.348 50.587  7.93    1    120.23 ? 404 LYS D CE  1 -0.342 0.464  0.02   
ATOM   12581 N  NZ  . LYS D 1 415 ? -37.888 50.681  9.328   1    111.44 ? 404 LYS D NZ  1 -0.347 0.464  0.023  
ATOM   12582 N  N   . ILE D 1 416 ? -32.632 53.254  4.583   1    100.96 ? 405 ILE D N   1 -0.299 0.488  0.011  
ATOM   12583 C  CA  . ILE D 1 416 ? -31.893 54.485  4.829   1    102.92 ? 405 ILE D CA  1 -0.292 0.499  0.012  
ATOM   12584 C  C   . ILE D 1 416 ? -31.875 55.381  3.575   1    104.42 ? 405 ILE D C   1 -0.292 0.508  0.009  
ATOM   12585 O  O   . ILE D 1 416 ? -31.644 56.587  3.684   1    100.88 ? 405 ILE D O   1 -0.29  0.519  0.009  
ATOM   12586 C  CB  . ILE D 1 416 ? -30.491 54.118  5.378   1    101.03 ? 405 ILE D CB  1 -0.279 0.496  0.013  
ATOM   12587 C  CG1 . ILE D 1 416 ? -30.531 53.726  6.874   1    110.8  ? 405 ILE D CG1 1 -0.28  0.492  0.017  
ATOM   12588 C  CG2 . ILE D 1 416 ? -29.51  55.271  5.256   1    96.54  ? 405 ILE D CG2 1 -0.27  0.507  0.013  
ATOM   12589 C  CD1 . ILE D 1 416 ? -31.624 52.705  7.361   1    109.19 ? 405 ILE D CD1 1 -0.29  0.483  0.018  
ATOM   12590 N  N   . LEU D 1 417 ? -32.166 54.835  2.385   1    106.47 ? 406 LEU D N   1 -0.295 0.503  0.006  
ATOM   12591 C  CA  . LEU D 1 417 ? -32.297 55.659  1.176   1    105.73 ? 406 LEU D CA  1 -0.296 0.51   0.003  
ATOM   12592 C  C   . LEU D 1 417 ? -33.695 56.271  1.073   1    106.85 ? 406 LEU D C   1 -0.309 0.516  0.003  
ATOM   12593 O  O   . LEU D 1 417 ? -33.84  57.495  0.968   1    106.07 ? 406 LEU D O   1 -0.31  0.527  0.002  
ATOM   12594 C  CB  . LEU D 1 417 ? -31.975 54.825  -0.078  1    108.28 ? 406 LEU D CB  1 -0.293 0.502  -0.0   
ATOM   12595 C  CG  . LEU D 1 417 ? -31.531 55.469  -1.408  1    109.59 ? 406 LEU D CG  1 -0.289 0.508  -0.004 
ATOM   12596 C  CD1 . LEU D 1 417 ? -32.681 56.077  -2.156  1    99.04  ? 406 LEU D CD1 1 -0.299 0.514  -0.005 
ATOM   12597 C  CD2 . LEU D 1 417 ? -30.467 56.522  -1.155  1    111.45 ? 406 LEU D CD2 1 -0.279 0.518  -0.003 
ATOM   12598 N  N   . LEU D 1 418 ? -34.735 55.431  1.134   1    106.08 ? 407 LEU D N   1 -0.318 0.508  0.003  
ATOM   12599 C  CA  . LEU D 1 418 ? -36.119 55.892  1.043   1    104.39 ? 407 LEU D CA  1 -0.331 0.512  0.003  
ATOM   12600 C  C   . LEU D 1 418 ? -36.463 56.929  2.105   1    105.89 ? 407 LEU D C   1 -0.334 0.522  0.005  
ATOM   12601 O  O   . LEU D 1 418 ? -37.413 57.703  1.922   1    101.26 ? 407 LEU D O   1 -0.343 0.529  0.005  
ATOM   12602 C  CB  . LEU D 1 418 ? -37.075 54.7    1.162   1    104.82 ? 407 LEU D CB  1 -0.34  0.501  0.003  
ATOM   12603 C  CG  . LEU D 1 418 ? -36.782 53.545  0.196   1    98.98  ? 407 LEU D CG  1 -0.337 0.491  0.0    
ATOM   12604 C  CD1 . LEU D 1 418 ? -37.893 52.483  0.17    1    86.36  ? 407 LEU D CD1 1 -0.347 0.481  0.0    
ATOM   12605 C  CD2 . LEU D 1 418 ? -36.501 54.116  -1.192  1    101.22 ? 407 LEU D CD2 1 -0.335 0.496  -0.003 
ATOM   12606 N  N   . GLN D 1 419 ? -35.729 56.953  3.219   1    111.95 ? 408 GLN D N   1 -0.327 0.522  0.008  
ATOM   12607 C  CA  . GLN D 1 419 ? -35.97  57.993  4.211   1    110.12 ? 408 GLN D CA  1 -0.33  0.531  0.011  
ATOM   12608 C  C   . GLN D 1 419 ? -35.377 59.32   3.75    1    109.8  ? 408 GLN D C   1 -0.324 0.544  0.009  
ATOM   12609 O  O   . GLN D 1 419 ? -36.005 60.377  3.911   1    106.2  ? 408 GLN D O   1 -0.33  0.553  0.01   
ATOM   12610 C  CB  . GLN D 1 419 ? -35.426 57.564  5.579   1    100.59 ? 408 GLN D CB  1 -0.325 0.528  0.014  
ATOM   12611 C  CG  . GLN D 1 419 ? -36.275 56.457  6.229   1    103.79 ? 408 GLN D CG  1 -0.332 0.517  0.016  
ATOM   12612 C  CD  . GLN D 1 419 ? -35.757 55.973  7.594   1    106.31 ? 408 GLN D CD  1 -0.328 0.513  0.019  
ATOM   12613 O  OE1 . GLN D 1 419 ? -36.522 55.408  8.383   1    105.61 ? 408 GLN D OE1 1 -0.335 0.508  0.021  
ATOM   12614 N  NE2 . GLN D 1 419 ? -34.463 56.179  7.867   1    100.68 ? 408 GLN D NE2 1 -0.316 0.515  0.02   
ATOM   12615 N  N   . VAL D 1 420 ? -34.192 59.29   3.127   1    106.06 ? 409 VAL D N   1 -0.313 0.543  0.008  
ATOM   12616 C  CA  . VAL D 1 420 ? -33.643 60.548  2.644   1    98.18  ? 409 VAL D CA  1 -0.308 0.555  0.007  
ATOM   12617 C  C   . VAL D 1 420 ? -34.488 61.07   1.5     1    105.57 ? 409 VAL D C   1 -0.316 0.56   0.004  
ATOM   12618 O  O   . VAL D 1 420 ? -34.598 62.286  1.309   1    105.63 ? 409 VAL D O   1 -0.317 0.571  0.003  
ATOM   12619 C  CB  . VAL D 1 420 ? -32.167 60.426  2.224   1    98.55  ? 409 VAL D CB  1 -0.295 0.554  0.006  
ATOM   12620 C  CG1 . VAL D 1 420 ? -31.511 61.814  2.213   1    102.36 ? 409 VAL D CG1 1 -0.289 0.566  0.006  
ATOM   12621 C  CG2 . VAL D 1 420 ? -31.411 59.482  3.12    1    94.46  ? 409 VAL D CG2 1 -0.288 0.545  0.008  
ATOM   12622 N  N   . ILE D 1 421 ? -35.102 60.18   0.717   1    106.15 ? 410 ILE D N   1 -0.322 0.551  0.002  
ATOM   12623 C  CA  . ILE D 1 421 ? -36     60.654  -0.332  1    107.57 ? 410 ILE D CA  1 -0.33  0.556  -0.001 
ATOM   12624 C  C   . ILE D 1 421 ? -37.217 61.31   0.293   1    104.82 ? 410 ILE D C   1 -0.341 0.562  0.001  
ATOM   12625 O  O   . ILE D 1 421 ? -37.506 62.484  0.046   1    108.48 ? 410 ILE D O   1 -0.344 0.573  0.0    
ATOM   12626 C  CB  . ILE D 1 421 ? -36.415 59.519  -1.282  1    107.19 ? 410 ILE D CB  1 -0.334 0.545  -0.003 
ATOM   12627 C  CG1 . ILE D 1 421 ? -35.246 58.648  -1.689  1    103.89 ? 410 ILE D CG1 1 -0.323 0.537  -0.004 
ATOM   12628 C  CG2 . ILE D 1 421 ? -36.921 60.098  -2.578  1    106.96 ? 410 ILE D CG2 1 -0.338 0.551  -0.006 
ATOM   12629 C  CD1 . ILE D 1 421 ? -35.69  57.557  -2.656  1    103.67 ? 410 ILE D CD1 1 -0.327 0.527  -0.007 
ATOM   12630 N  N   . GLU D 1 422 ? -37.943 60.565  1.124   1    107.33 ? 411 GLU D N   1 -0.348 0.555  0.003  
ATOM   12631 C  CA  . GLU D 1 422 ? -39.18  61.096  1.69    1    106.19 ? 411 GLU D CA  1 -0.359 0.56   0.004  
ATOM   12632 C  C   . GLU D 1 422 ? -38.966 62.475  2.304   1    107.49 ? 411 GLU D C   1 -0.357 0.573  0.006  
ATOM   12633 O  O   . GLU D 1 422 ? -39.751 63.403  2.062   1    101.84 ? 411 GLU D O   1 -0.364 0.581  0.005  
ATOM   12634 C  CB  . GLU D 1 422 ? -39.735 60.117  2.718   1    102.87 ? 411 GLU D CB  1 -0.364 0.551  0.007  
ATOM   12635 C  CG  . GLU D 1 422 ? -41.243 60.127  2.778   1    111.47 ? 411 GLU D CG  1 -0.378 0.551  0.007  
ATOM   12636 C  CD  . GLU D 1 422 ? -41.821 59.294  3.928   1    124.53 ? 411 GLU D CD  1 -0.383 0.543  0.01   
ATOM   12637 O  OE1 . GLU D 1 422 ? -41.287 59.335  5.068   1    126.93 ? 411 GLU D OE1 1 -0.378 0.544  0.013  
ATOM   12638 O  OE2 . GLU D 1 422 ? -42.836 58.599  3.685   1    124.19 ? 411 GLU D OE2 1 -0.393 0.537  0.009  
ATOM   12639 N  N   . LYS D 1 423 ? -37.876 62.639  3.074   1    109.83 ? 412 LYS D N   1 -0.347 0.574  0.008  
ATOM   12640 C  CA  . LYS D 1 423 ? -37.583 63.933  3.697   1    107.02 ? 412 LYS D CA  1 -0.344 0.586  0.009  
ATOM   12641 C  C   . LYS D 1 423 ? -37.287 65.002  2.651   1    108.91 ? 412 LYS D C   1 -0.342 0.596  0.007  
ATOM   12642 O  O   . LYS D 1 423 ? -37.795 66.124  2.745   1    110.5  ? 412 LYS D O   1 -0.346 0.606  0.007  
ATOM   12643 C  CB  . LYS D 1 423 ? -36.419 63.797  4.685   1    100.2  ? 412 LYS D CB  1 -0.334 0.585  0.012  
ATOM   12644 C  CG  . LYS D 1 423 ? -36.755 62.882  5.885   1    122.31 ? 412 LYS D CG  1 -0.337 0.576  0.015  
ATOM   12645 C  CD  . LYS D 1 423 ? -35.838 63.05   7.137   1    120.09 ? 412 LYS D CD  1 -0.328 0.578  0.018  
ATOM   12646 C  CE  . LYS D 1 423 ? -34.402 62.529  6.92    1    116.05 ? 412 LYS D CE  1 -0.315 0.573  0.017  
ATOM   12647 N  NZ  . LYS D 1 423 ? -33.549 63.377  5.988   1    106.78 ? 412 LYS D NZ  1 -0.307 0.581  0.015  
ATOM   12648 N  N   . GLN D 1 424 ? -36.49  64.671  1.636   1    109.97 ? 413 GLN D N   1 -0.334 0.593  0.004  
ATOM   12649 C  CA  . GLN D 1 424 ? -35.897 65.697  0.784   1    111.97 ? 413 GLN D CA  1 -0.329 0.602  0.002  
ATOM   12650 C  C   . GLN D 1 424 ? -36.657 65.958  -0.508  1    110.31 ? 413 GLN D C   1 -0.336 0.604  -0.001 
ATOM   12651 O  O   . GLN D 1 424 ? -36.63  67.095  -0.995  1    107.26 ? 413 GLN D O   1 -0.336 0.615  -0.002 
ATOM   12652 C  CB  . GLN D 1 424 ? -34.443 65.333  0.444   1    109.67 ? 413 GLN D CB  1 -0.316 0.599  0.001  
ATOM   12653 C  CG  . GLN D 1 424 ? -33.418 65.687  1.528   1    107.21 ? 413 GLN D CG  1 -0.306 0.602  0.004  
ATOM   12654 C  CD  . GLN D 1 424 ? -32.582 66.923  1.18    1    114.34 ? 413 GLN D CD  1 -0.299 0.613  0.003  
ATOM   12655 O  OE1 . GLN D 1 424 ? -33.082 67.888  0.587   1    117.11 ? 413 GLN D OE1 1 -0.303 0.622  0.001  
ATOM   12656 N  NE2 . GLN D 1 424 ? -31.299 66.889  1.536   1    112.06 ? 413 GLN D NE2 1 -0.287 0.613  0.004  
ATOM   12657 N  N   . LEU D 1 425 ? -37.35  64.947  -1.057  1    117.23 ? 414 LEU D N   1 -0.342 0.595  -0.003 
ATOM   12658 C  CA  . LEU D 1 425 ? -37.791 64.94   -2.453  1    113.03 ? 414 LEU D CA  1 -0.346 0.595  -0.006 
ATOM   12659 C  C   . LEU D 1 425 ? -39.276 64.636  -2.634  1    112.5  ? 414 LEU D C   1 -0.36  0.592  -0.007 
ATOM   12660 O  O   . LEU D 1 425 ? -39.704 64.408  -3.767  1    123.09 ? 414 LEU D O   1 -0.364 0.59   -0.009 
ATOM   12661 C  CB  . LEU D 1 425 ? -36.974 63.915  -3.262  1    114.17 ? 414 LEU D CB  1 -0.339 0.586  -0.008 
ATOM   12662 C  CG  . LEU D 1 425 ? -35.7   64.253  -4.064  1    113.07 ? 414 LEU D CG  1 -0.327 0.589  -0.01  
ATOM   12663 C  CD1 . LEU D 1 425 ? -34.787 65.228  -3.347  1    113.31 ? 414 LEU D CD1 1 -0.319 0.598  -0.008 
ATOM   12664 C  CD2 . LEU D 1 425 ? -34.915 62.983  -4.407  1    105.76 ? 414 LEU D CD2 1 -0.32  0.577  -0.011 
ATOM   12665 N  N   . LEU D 1 426 ? -40.068 64.608  -1.566  1    117.02 ? 415 LEU D N   1 -0.367 0.592  -0.004 
ATOM   12666 C  CA  . LEU D 1 426 ? -41.495 64.316  -1.669  1    125.28 ? 415 LEU D CA  1 -0.38  0.589  -0.004 
ATOM   12667 C  C   . LEU D 1 426 ? -42.284 65.263  -0.775  1    135.24 ? 415 LEU D C   1 -0.387 0.598  -0.002 
ATOM   12668 O  O   . LEU D 1 426 ? -41.797 65.679  0.285   1    132.57 ? 415 LEU D O   1 -0.383 0.602  0.001  
ATOM   12669 C  CB  . LEU D 1 426 ? -41.83  62.859  -1.3    1    117.16 ? 415 LEU D CB  1 -0.383 0.576  -0.003 
ATOM   12670 C  CG  . LEU D 1 426 ? -41.318 61.718  -2.177  1    124.48 ? 415 LEU D CG  1 -0.379 0.566  -0.005 
ATOM   12671 C  CD1 . LEU D 1 426 ? -39.907 61.335  -1.741  1    118.15 ? 415 LEU D CD1 1 -0.366 0.562  -0.004 
ATOM   12672 C  CD2 . LEU D 1 426 ? -42.333 60.543  -2.126  1    128.59 ? 415 LEU D CD2 1 -0.388 0.555  -0.005 
ATOM   12673 N  N   . PRO D 1 427 ? -43.501 65.639  -1.187  1    147.72 ? 416 PRO D N   1 -0.399 0.602  -0.003 
ATOM   12674 C  CA  . PRO D 1 427 ? -44.261 66.635  -0.415  1    146.83 ? 416 PRO D CA  1 -0.406 0.611  -0.001 
ATOM   12675 C  C   . PRO D 1 427 ? -45.248 66.023  0.572   1    148.36 ? 416 PRO D C   1 -0.415 0.605  0.001  
ATOM   12676 O  O   . PRO D 1 427 ? -46.053 65.159  0.208   1    150.57 ? 416 PRO D O   1 -0.422 0.597  0.001  
ATOM   12677 C  CB  . PRO D 1 427 ? -44.98  67.442  -1.51   1    154.23 ? 416 PRO D CB  1 -0.412 0.618  -0.004 
ATOM   12678 C  CG  . PRO D 1 427 ? -44.922 66.555  -2.804  1    145.5  ? 416 PRO D CG  1 -0.412 0.61   -0.007 
ATOM   12679 C  CD  . PRO D 1 427 ? -44.165 65.298  -2.461  1    142.96 ? 416 PRO D CD  1 -0.405 0.598  -0.006 
ATOM   12680 N  N   . LYS D 1 428 ? -45.192 66.472  1.825   1    158.12 ? 417 LYS D N   1 -0.414 0.609  0.005  
ATOM   12681 C  CA  . LYS D 1 428 ? -46.122 66.027  2.868   1    158.13 ? 417 LYS D CA  1 -0.423 0.605  0.007  
ATOM   12682 C  C   . LYS D 1 428 ? -46.552 67.211  3.727   1    156.06 ? 417 LYS D C   1 -0.427 0.616  0.009  
ATOM   12683 O  O   . LYS D 1 428 ? -47.698 67.292  4.164   1    159.47 ? 417 LYS D O   1 -0.437 0.617  0.01   
ATOM   12684 C  CB  . LYS D 1 428 ? -45.49  64.933  3.744   1    155.61 ? 417 LYS D CB  1 -0.417 0.595  0.009  
ATOM   12685 C  CG  . LYS D 1 428 ? -46.284 64.568  5.011   1    158.03 ? 417 LYS D CG  1 -0.424 0.592  0.013  
ATOM   12686 C  CD  . LYS D 1 428 ? -47.712 64.119  4.694   1    161.03 ? 417 LYS D CD  1 -0.437 0.588  0.012  
ATOM   12687 C  CE  . LYS D 1 428 ? -47.735 62.955  3.702   1    160.35 ? 417 LYS D CE  1 -0.437 0.577  0.009  
ATOM   12688 N  NZ  . LYS D 1 428 ? -48.958 62.964  2.844   1    153.97 ? 417 LYS D NZ  1 -0.449 0.577  0.007  
HETATM 12689 ZN ZN  . ZN  E 2 .   ? -24.256 21.886  1.503   0.7  103.32 ? 501 ZN  A ZN  1 -0.222 0.201  0.004  
HETATM 12690 K  K   . K   F 3 .   ? -30.524 19.167  0.698   1    100.38 ? 502 K   A K   1 -0.28  0.176  0.002  
HETATM 12691 ZN ZN  . ZN  G 2 .   ? -30.837 76.639  23.624  0.67 101.8  ? 501 ZN  B ZN  1 -0.283 0.702  0.059  
HETATM 12692 ZN ZN  . ZN  H 2 .   ? -33.799 -9.041  33.464  0.8  113.48 ? 501 ZN  C ZN  1 -0.31  -0.083 0.084  
HETATM 12693 K  K   . K   I 3 .   ? -36.262 -2.19   34.628  1    113.2  ? 502 K   C K   1 -0.332 -0.02  0.086  
HETATM 12694 ZN ZN  . ZN  J 2 .   ? -20.579 45.4    -8.085  0.72 111.43 ? 501 ZN  D ZN  1 -0.189 0.416  -0.02  
HETATM 12695 O  O   . HOH K 4 .   ? -41.23  30.578  -14.294 1    99.45  ? 601 HOH A O   1 -0.378 0.28   -0.036 
HETATM 12696 O  O   . HOH K 4 .   ? -13.777 29.347  1.747   1    104.07 ? 602 HOH A O   1 -0.126 0.269  0.004  
HETATM 12697 O  O   . HOH K 4 .   ? -38.207 10.441  17.989  1    89.58  ? 603 HOH A O   1 -0.35  0.096  0.045  
HETATM 12698 O  O   . HOH K 4 .   ? -16.829 29.83   6.208   1    95.34  ? 604 HOH A O   1 -0.154 0.273  0.016  
HETATM 12699 O  O   . HOH L 4 .   ? -24.248 73.691  24.332  1    81.16  ? 601 HOH B O   1 -0.222 0.675  0.061  
HETATM 12700 O  O   . HOH L 4 .   ? -16.438 65.23   7.154   1    97.35  ? 602 HOH B O   1 -0.151 0.598  0.018  
HETATM 12701 O  O   . HOH L 4 .   ? -13.906 85.312  40.325  1    102.71 ? 603 HOH B O   1 -0.127 0.782  0.101  
HETATM 12702 O  O   . HOH L 4 .   ? -36.370 92.007  33.768  1    132.79 ? 604 HOH B O   1 -0.333 -0.157 0.084  
HETATM 12703 O  O   . HOH M 4 .   ? -34.51  -11.001 33.268  1    111.92 ? 601 HOH C O   1 -0.316 -0.101 0.083  
HETATM 12704 O  O   . HOH M 4 .   ? -31.704 -9.582  35.261  1    99.64  ? 602 HOH C O   1 -0.291 -0.088 0.088  
HETATM 12705 O  O   . HOH M 4 .   ? -25.802 -13.629 63.36   1    90.36  ? 603 HOH C O   1 -0.236 -0.125 0.158  
HETATM 12706 O  O   . HOH M 4 .   ? -33.862 -10.831 35.22   1    117.96 ? 604 HOH C O   1 -0.31  -0.099 0.088  
HETATM 12707 O  O   . HOH N 4 .   ? -17.976 52.234  -9.179  1    99.47  ? 601 HOH D O   1 -0.165 0.479  -0.023 
HETATM 12708 O  O   . HOH N 4 .   ? -28.881 40.969  -38.535 1    101.71 ? 602 HOH D O   1 -0.265 0.375  -0.096 
HETATM 12709 O  O   . HOH N 4 .   ? -22.928 45.211  -10.12  1    99.56  ? 603 HOH D O   1 -0.21  0.414  -0.025 
HETATM 12710 O  O   . HOH N 4 .   ? -12.514 47.435  -9.803  1    111.36 ? 604 HOH D O   1 -0.115 0.435  -0.024 
HETATM 12711 O  O   . HOH N 4 .   ? -18.483 38.507  -9.834  1    113.27 ? 605 HOH D O   1 -0.169 0.353  -0.025 
HETATM 12712 O  O   . HOH N 4 .   ? -22.117 29.653  0.271   1    118.8  ? 606 HOH D O   1 -0.203 0.272  0.001  
# 
