data_9GIF
# 
_entry.id   9GIF 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GIF         pdb_00009gif 10.2210/pdb9gif/pdb 
WWPDB D_1292139334 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-27 
2 'Structure model' 1 1 2024-12-11 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GIF 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB-Dev '7 pdbs for 1 paper' D_1292139329 unspecified 
PDB-Dev .                    D_1292139330 unspecified 
PDB-Dev .                    D_1292139331 unspecified 
PDB-Dev .                    D_1292139332 unspecified 
PDB-Dev .                    D_1292139333 unspecified 
PDB-Dev .                    D_1292138744 unspecified 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              easc@lundbeck.com 
_pdbx_contact_author.name_first         Erhad 
_pdbx_contact_author.name_last          Ascic 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0009-0005-4917-2027 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Carr, K.H.'    1 0000-0002-9772-2733 
'Ascic, E.'     2 0009-0005-4917-2027 
'Leonard, P.M.' 3 0000-0002-2988-5557 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Med.Chem. 
_citation.journal_id_ASTM           JMCMAR 
_citation.journal_id_CSD            0151 
_citation.journal_id_ISSN           0022-2623 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            67 
_citation.language                  ? 
_citation.page_first                20135 
_citation.page_last                 20155 
_citation.title                     
'Advancements in NMDA Receptor-Targeted Antidepressants: From d-Cycloserine Discovery to Preclinical Efficacy of Lu AF90103.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.jmedchem.4c01477 
_citation.pdbx_database_id_PubMed   39560374 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ascic, E.'         1  ? 
primary 'Marigo, M.'        2  ? 
primary 'David, L.'         3  ? 
primary 'Frisch Herrik, K.' 4  ? 
primary 'Grupe, M.'         5  ? 
primary 'Hougaard, C.'      6  ? 
primary 'Mork, A.'          7  ? 
primary 'Jones, C.R.'       8  ? 
primary 'Badolo, L.'        9  ? 
primary 'Frederiksen, K.'   10 ? 
primary 'Boonen, H.C.M.'    11 ? 
primary 'Jensen, H.S.'      12 ? 
primary 'Kilburn, J.P.'     13 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Glutamate receptor ionotropic, NMDA 1'                               33422.141 1   ? ? ? ? 
2 non-polymer syn '(2~{R})-2-azanyl-3-(2~{H}-thiophen-5-ylcarbonylamino)propanoic acid' 216.257   1   ? ? ? ? 
3 non-polymer syn 'SULFATE ION'                                                         96.063    1   ? ? ? ? 
4 water       nat water                                                                 18.015    218 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFT
YEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKGTRITGIND
PRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTT
GELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSR
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFT
YEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKGTRITGIND
PRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTT
GELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSR
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '(2~{R})-2-azanyl-3-(2~{H}-thiophen-5-ylcarbonylamino)propanoic acid' A1ILR 
3 'SULFATE ION'                                                         SO4   
4 water                                                                 HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   THR n 
1 4   ARG n 
1 5   LEU n 
1 6   LYS n 
1 7   ILE n 
1 8   VAL n 
1 9   THR n 
1 10  ILE n 
1 11  HIS n 
1 12  GLN n 
1 13  GLU n 
1 14  PRO n 
1 15  PHE n 
1 16  VAL n 
1 17  TYR n 
1 18  VAL n 
1 19  LYS n 
1 20  PRO n 
1 21  THR n 
1 22  LEU n 
1 23  SER n 
1 24  ASP n 
1 25  GLY n 
1 26  THR n 
1 27  CYS n 
1 28  LYS n 
1 29  GLU n 
1 30  GLU n 
1 31  PHE n 
1 32  THR n 
1 33  VAL n 
1 34  ASN n 
1 35  GLY n 
1 36  ASP n 
1 37  PRO n 
1 38  VAL n 
1 39  LYS n 
1 40  LYS n 
1 41  VAL n 
1 42  ILE n 
1 43  CYS n 
1 44  THR n 
1 45  GLY n 
1 46  PRO n 
1 47  ASN n 
1 48  ASP n 
1 49  THR n 
1 50  SER n 
1 51  PRO n 
1 52  GLY n 
1 53  SER n 
1 54  PRO n 
1 55  ARG n 
1 56  HIS n 
1 57  THR n 
1 58  VAL n 
1 59  PRO n 
1 60  GLN n 
1 61  CYS n 
1 62  CYS n 
1 63  TYR n 
1 64  GLY n 
1 65  PHE n 
1 66  CYS n 
1 67  ILE n 
1 68  ASP n 
1 69  LEU n 
1 70  LEU n 
1 71  ILE n 
1 72  LYS n 
1 73  LEU n 
1 74  ALA n 
1 75  ARG n 
1 76  THR n 
1 77  MET n 
1 78  ASN n 
1 79  PHE n 
1 80  THR n 
1 81  TYR n 
1 82  GLU n 
1 83  VAL n 
1 84  HIS n 
1 85  LEU n 
1 86  VAL n 
1 87  ALA n 
1 88  ASP n 
1 89  GLY n 
1 90  LYS n 
1 91  PHE n 
1 92  GLY n 
1 93  THR n 
1 94  GLN n 
1 95  GLU n 
1 96  ARG n 
1 97  VAL n 
1 98  ASN n 
1 99  ASN n 
1 100 SER n 
1 101 ASN n 
1 102 LYS n 
1 103 LYS n 
1 104 GLU n 
1 105 TRP n 
1 106 ASN n 
1 107 GLY n 
1 108 MET n 
1 109 MET n 
1 110 GLY n 
1 111 GLU n 
1 112 LEU n 
1 113 LEU n 
1 114 SER n 
1 115 GLY n 
1 116 GLN n 
1 117 ALA n 
1 118 ASP n 
1 119 MET n 
1 120 ILE n 
1 121 VAL n 
1 122 ALA n 
1 123 PRO n 
1 124 LEU n 
1 125 THR n 
1 126 ILE n 
1 127 ASN n 
1 128 ASN n 
1 129 GLU n 
1 130 ARG n 
1 131 ALA n 
1 132 GLN n 
1 133 TYR n 
1 134 ILE n 
1 135 GLU n 
1 136 PHE n 
1 137 SER n 
1 138 LYS n 
1 139 PRO n 
1 140 PHE n 
1 141 LYS n 
1 142 TYR n 
1 143 GLN n 
1 144 GLY n 
1 145 LEU n 
1 146 THR n 
1 147 ILE n 
1 148 LEU n 
1 149 VAL n 
1 150 LYS n 
1 151 LYS n 
1 152 GLY n 
1 153 THR n 
1 154 ARG n 
1 155 ILE n 
1 156 THR n 
1 157 GLY n 
1 158 ILE n 
1 159 ASN n 
1 160 ASP n 
1 161 PRO n 
1 162 ARG n 
1 163 LEU n 
1 164 ARG n 
1 165 ASN n 
1 166 PRO n 
1 167 SER n 
1 168 ASP n 
1 169 LYS n 
1 170 PHE n 
1 171 ILE n 
1 172 TYR n 
1 173 ALA n 
1 174 THR n 
1 175 VAL n 
1 176 LYS n 
1 177 GLN n 
1 178 SER n 
1 179 SER n 
1 180 VAL n 
1 181 ASP n 
1 182 ILE n 
1 183 TYR n 
1 184 PHE n 
1 185 ARG n 
1 186 ARG n 
1 187 GLN n 
1 188 VAL n 
1 189 GLU n 
1 190 LEU n 
1 191 SER n 
1 192 THR n 
1 193 MET n 
1 194 TYR n 
1 195 ARG n 
1 196 HIS n 
1 197 MET n 
1 198 GLU n 
1 199 LYS n 
1 200 HIS n 
1 201 ASN n 
1 202 TYR n 
1 203 GLU n 
1 204 SER n 
1 205 ALA n 
1 206 ALA n 
1 207 GLU n 
1 208 ALA n 
1 209 ILE n 
1 210 GLN n 
1 211 ALA n 
1 212 VAL n 
1 213 ARG n 
1 214 ASP n 
1 215 ASN n 
1 216 LYS n 
1 217 LEU n 
1 218 HIS n 
1 219 ALA n 
1 220 PHE n 
1 221 ILE n 
1 222 TRP n 
1 223 ASP n 
1 224 SER n 
1 225 ALA n 
1 226 VAL n 
1 227 LEU n 
1 228 GLU n 
1 229 PHE n 
1 230 GLU n 
1 231 ALA n 
1 232 SER n 
1 233 GLN n 
1 234 LYS n 
1 235 CYS n 
1 236 ASP n 
1 237 LEU n 
1 238 VAL n 
1 239 THR n 
1 240 THR n 
1 241 GLY n 
1 242 GLU n 
1 243 LEU n 
1 244 PHE n 
1 245 PHE n 
1 246 ARG n 
1 247 SER n 
1 248 GLY n 
1 249 PHE n 
1 250 GLY n 
1 251 ILE n 
1 252 GLY n 
1 253 MET n 
1 254 ARG n 
1 255 LYS n 
1 256 ASP n 
1 257 SER n 
1 258 PRO n 
1 259 TRP n 
1 260 LYS n 
1 261 GLN n 
1 262 ASN n 
1 263 VAL n 
1 264 SER n 
1 265 LEU n 
1 266 SER n 
1 267 ILE n 
1 268 LEU n 
1 269 LYS n 
1 270 SER n 
1 271 HIS n 
1 272 GLU n 
1 273 ASN n 
1 274 GLY n 
1 275 PHE n 
1 276 MET n 
1 277 GLU n 
1 278 ASP n 
1 279 LEU n 
1 280 ASP n 
1 281 LYS n 
1 282 THR n 
1 283 TRP n 
1 284 VAL n 
1 285 ARG n 
1 286 TYR n 
1 287 GLN n 
1 288 GLU n 
1 289 CYS n 
1 290 ASP n 
1 291 SER n 
1 292 ARG n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   151 human ? 'GRIN1, NMDAR1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? 'Rosetta-gami (DE3)' ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 152 292 human ? 'GRIN1, NMDAR1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? 'Rosetta-gami (DE3)' ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1ILR non-polymer         . '(2~{R})-2-azanyl-3-(2~{H}-thiophen-5-ylcarbonylamino)propanoic acid' ? 'C8 H12 N2 O3 S' 216.257 
ALA   'L-peptide linking' y ALANINE                                                               ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                                                              ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE                                                            ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'                                                       ? 'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE                                                              ? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE                                                             ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                                                       ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                                                               ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE                                                             ? 'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                                                                 ? 'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE                                                            ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                                                               ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                                                                ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE                                                            ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE                                                         ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                                                               ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                                                                ? 'C3 H7 N O3'     105.093 
SO4   non-polymer         . 'SULFATE ION'                                                         ? 'O4 S -2'        96.063  
THR   'L-peptide linking' y THREONINE                                                             ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN                                                            ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                                                              ? 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                                                                ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   394 ?   ?   ?   A . n 
A 1 2   SER 2   395 ?   ?   ?   A . n 
A 1 3   THR 3   396 ?   ?   ?   A . n 
A 1 4   ARG 4   397 397 ARG ARG A . n 
A 1 5   LEU 5   398 398 LEU LEU A . n 
A 1 6   LYS 6   399 399 LYS LYS A . n 
A 1 7   ILE 7   400 400 ILE ILE A . n 
A 1 8   VAL 8   401 401 VAL VAL A . n 
A 1 9   THR 9   402 402 THR THR A . n 
A 1 10  ILE 10  403 403 ILE ILE A . n 
A 1 11  HIS 11  404 404 HIS HIS A . n 
A 1 12  GLN 12  405 405 GLN GLN A . n 
A 1 13  GLU 13  406 406 GLU GLU A . n 
A 1 14  PRO 14  407 407 PRO PRO A . n 
A 1 15  PHE 15  408 408 PHE PHE A . n 
A 1 16  VAL 16  409 409 VAL VAL A . n 
A 1 17  TYR 17  410 410 TYR TYR A . n 
A 1 18  VAL 18  411 411 VAL VAL A . n 
A 1 19  LYS 19  412 412 LYS LYS A . n 
A 1 20  PRO 20  413 413 PRO PRO A . n 
A 1 21  THR 21  414 414 THR THR A . n 
A 1 22  LEU 22  415 415 LEU LEU A . n 
A 1 23  SER 23  416 416 SER SER A . n 
A 1 24  ASP 24  417 417 ASP ASP A . n 
A 1 25  GLY 25  418 418 GLY GLY A . n 
A 1 26  THR 26  419 419 THR THR A . n 
A 1 27  CYS 27  420 420 CYS CYS A . n 
A 1 28  LYS 28  421 421 LYS LYS A . n 
A 1 29  GLU 29  422 422 GLU GLU A . n 
A 1 30  GLU 30  423 423 GLU GLU A . n 
A 1 31  PHE 31  424 424 PHE PHE A . n 
A 1 32  THR 32  425 425 THR THR A . n 
A 1 33  VAL 33  426 426 VAL VAL A . n 
A 1 34  ASN 34  427 427 ASN ASN A . n 
A 1 35  GLY 35  428 428 GLY GLY A . n 
A 1 36  ASP 36  429 429 ASP ASP A . n 
A 1 37  PRO 37  430 430 PRO PRO A . n 
A 1 38  VAL 38  431 431 VAL VAL A . n 
A 1 39  LYS 39  432 432 LYS LYS A . n 
A 1 40  LYS 40  433 433 LYS LYS A . n 
A 1 41  VAL 41  434 434 VAL VAL A . n 
A 1 42  ILE 42  435 435 ILE ILE A . n 
A 1 43  CYS 43  436 436 CYS CYS A . n 
A 1 44  THR 44  437 437 THR THR A . n 
A 1 45  GLY 45  438 438 GLY GLY A . n 
A 1 46  PRO 46  439 439 PRO PRO A . n 
A 1 47  ASN 47  440 440 ASN ASN A . n 
A 1 48  ASP 48  441 441 ASP ASP A . n 
A 1 49  THR 49  442 442 THR THR A . n 
A 1 50  SER 50  443 443 SER SER A . n 
A 1 51  PRO 51  444 444 PRO PRO A . n 
A 1 52  GLY 52  445 445 GLY GLY A . n 
A 1 53  SER 53  446 446 SER SER A . n 
A 1 54  PRO 54  447 447 PRO PRO A . n 
A 1 55  ARG 55  448 448 ARG ARG A . n 
A 1 56  HIS 56  449 449 HIS HIS A . n 
A 1 57  THR 57  450 450 THR THR A . n 
A 1 58  VAL 58  451 451 VAL VAL A . n 
A 1 59  PRO 59  452 452 PRO PRO A . n 
A 1 60  GLN 60  453 453 GLN GLN A . n 
A 1 61  CYS 61  454 454 CYS CYS A . n 
A 1 62  CYS 62  455 455 CYS CYS A . n 
A 1 63  TYR 63  456 456 TYR TYR A . n 
A 1 64  GLY 64  457 457 GLY GLY A . n 
A 1 65  PHE 65  458 458 PHE PHE A . n 
A 1 66  CYS 66  459 459 CYS CYS A . n 
A 1 67  ILE 67  460 460 ILE ILE A . n 
A 1 68  ASP 68  461 461 ASP ASP A . n 
A 1 69  LEU 69  462 462 LEU LEU A . n 
A 1 70  LEU 70  463 463 LEU LEU A . n 
A 1 71  ILE 71  464 464 ILE ILE A . n 
A 1 72  LYS 72  465 465 LYS LYS A . n 
A 1 73  LEU 73  466 466 LEU LEU A . n 
A 1 74  ALA 74  467 467 ALA ALA A . n 
A 1 75  ARG 75  468 468 ARG ARG A . n 
A 1 76  THR 76  469 469 THR THR A . n 
A 1 77  MET 77  470 470 MET MET A . n 
A 1 78  ASN 78  471 471 ASN ASN A . n 
A 1 79  PHE 79  472 472 PHE PHE A . n 
A 1 80  THR 80  473 473 THR THR A . n 
A 1 81  TYR 81  474 474 TYR TYR A . n 
A 1 82  GLU 82  475 475 GLU GLU A . n 
A 1 83  VAL 83  476 476 VAL VAL A . n 
A 1 84  HIS 84  477 477 HIS HIS A . n 
A 1 85  LEU 85  478 478 LEU LEU A . n 
A 1 86  VAL 86  479 479 VAL VAL A . n 
A 1 87  ALA 87  480 480 ALA ALA A . n 
A 1 88  ASP 88  481 481 ASP ASP A . n 
A 1 89  GLY 89  482 482 GLY GLY A . n 
A 1 90  LYS 90  483 483 LYS LYS A . n 
A 1 91  PHE 91  484 484 PHE PHE A . n 
A 1 92  GLY 92  485 485 GLY GLY A . n 
A 1 93  THR 93  486 486 THR THR A . n 
A 1 94  GLN 94  487 487 GLN GLN A . n 
A 1 95  GLU 95  488 488 GLU GLU A . n 
A 1 96  ARG 96  489 489 ARG ARG A . n 
A 1 97  VAL 97  490 490 VAL VAL A . n 
A 1 98  ASN 98  491 491 ASN ASN A . n 
A 1 99  ASN 99  492 492 ASN ASN A . n 
A 1 100 SER 100 493 493 SER SER A . n 
A 1 101 ASN 101 494 494 ASN ASN A . n 
A 1 102 LYS 102 495 495 LYS LYS A . n 
A 1 103 LYS 103 496 496 LYS LYS A . n 
A 1 104 GLU 104 497 497 GLU GLU A . n 
A 1 105 TRP 105 498 498 TRP TRP A . n 
A 1 106 ASN 106 499 499 ASN ASN A . n 
A 1 107 GLY 107 500 500 GLY GLY A . n 
A 1 108 MET 108 501 501 MET MET A . n 
A 1 109 MET 109 502 502 MET MET A . n 
A 1 110 GLY 110 503 503 GLY GLY A . n 
A 1 111 GLU 111 504 504 GLU GLU A . n 
A 1 112 LEU 112 505 505 LEU LEU A . n 
A 1 113 LEU 113 506 506 LEU LEU A . n 
A 1 114 SER 114 507 507 SER SER A . n 
A 1 115 GLY 115 508 508 GLY GLY A . n 
A 1 116 GLN 116 509 509 GLN GLN A . n 
A 1 117 ALA 117 510 510 ALA ALA A . n 
A 1 118 ASP 118 511 511 ASP ASP A . n 
A 1 119 MET 119 512 512 MET MET A . n 
A 1 120 ILE 120 513 513 ILE ILE A . n 
A 1 121 VAL 121 514 514 VAL VAL A . n 
A 1 122 ALA 122 515 515 ALA ALA A . n 
A 1 123 PRO 123 516 516 PRO PRO A . n 
A 1 124 LEU 124 517 517 LEU LEU A . n 
A 1 125 THR 125 518 518 THR THR A . n 
A 1 126 ILE 126 519 519 ILE ILE A . n 
A 1 127 ASN 127 520 520 ASN ASN A . n 
A 1 128 ASN 128 521 521 ASN ASN A . n 
A 1 129 GLU 129 522 522 GLU GLU A . n 
A 1 130 ARG 130 523 523 ARG ARG A . n 
A 1 131 ALA 131 524 524 ALA ALA A . n 
A 1 132 GLN 132 525 525 GLN GLN A . n 
A 1 133 TYR 133 526 526 TYR TYR A . n 
A 1 134 ILE 134 527 527 ILE ILE A . n 
A 1 135 GLU 135 528 528 GLU GLU A . n 
A 1 136 PHE 136 529 529 PHE PHE A . n 
A 1 137 SER 137 530 530 SER SER A . n 
A 1 138 LYS 138 531 531 LYS LYS A . n 
A 1 139 PRO 139 532 532 PRO PRO A . n 
A 1 140 PHE 140 533 533 PHE PHE A . n 
A 1 141 LYS 141 534 534 LYS LYS A . n 
A 1 142 TYR 142 535 535 TYR TYR A . n 
A 1 143 GLN 143 536 536 GLN GLN A . n 
A 1 144 GLY 144 537 537 GLY GLY A . n 
A 1 145 LEU 145 538 538 LEU LEU A . n 
A 1 146 THR 146 539 539 THR THR A . n 
A 1 147 ILE 147 540 540 ILE ILE A . n 
A 1 148 LEU 148 541 541 LEU LEU A . n 
A 1 149 VAL 149 542 542 VAL VAL A . n 
A 1 150 LYS 150 543 543 LYS LYS A . n 
A 1 151 LYS 151 544 544 LYS LYS A . n 
A 1 152 GLY 152 545 545 GLY GLY A . n 
A 1 153 THR 153 546 546 THR THR A . n 
A 1 154 ARG 154 663 663 ARG ARG A . n 
A 1 155 ILE 155 664 664 ILE ILE A . n 
A 1 156 THR 156 665 665 THR THR A . n 
A 1 157 GLY 157 666 666 GLY GLY A . n 
A 1 158 ILE 158 667 667 ILE ILE A . n 
A 1 159 ASN 159 668 668 ASN ASN A . n 
A 1 160 ASP 160 669 669 ASP ASP A . n 
A 1 161 PRO 161 670 670 PRO PRO A . n 
A 1 162 ARG 162 671 671 ARG ARG A . n 
A 1 163 LEU 163 672 672 LEU LEU A . n 
A 1 164 ARG 164 673 673 ARG ARG A . n 
A 1 165 ASN 165 674 674 ASN ASN A . n 
A 1 166 PRO 166 675 675 PRO PRO A . n 
A 1 167 SER 167 676 676 SER SER A . n 
A 1 168 ASP 168 677 677 ASP ASP A . n 
A 1 169 LYS 169 678 678 LYS LYS A . n 
A 1 170 PHE 170 679 679 PHE PHE A . n 
A 1 171 ILE 171 680 680 ILE ILE A . n 
A 1 172 TYR 172 681 681 TYR TYR A . n 
A 1 173 ALA 173 682 682 ALA ALA A . n 
A 1 174 THR 174 683 683 THR THR A . n 
A 1 175 VAL 175 684 684 VAL VAL A . n 
A 1 176 LYS 176 685 685 LYS LYS A . n 
A 1 177 GLN 177 686 686 GLN GLN A . n 
A 1 178 SER 178 687 687 SER SER A . n 
A 1 179 SER 179 688 688 SER SER A . n 
A 1 180 VAL 180 689 689 VAL VAL A . n 
A 1 181 ASP 181 690 690 ASP ASP A . n 
A 1 182 ILE 182 691 691 ILE ILE A . n 
A 1 183 TYR 183 692 692 TYR TYR A . n 
A 1 184 PHE 184 693 693 PHE PHE A . n 
A 1 185 ARG 185 694 694 ARG ARG A . n 
A 1 186 ARG 186 695 695 ARG ARG A . n 
A 1 187 GLN 187 696 696 GLN GLN A . n 
A 1 188 VAL 188 697 697 VAL VAL A . n 
A 1 189 GLU 189 698 698 GLU GLU A . n 
A 1 190 LEU 190 699 699 LEU LEU A . n 
A 1 191 SER 191 700 700 SER SER A . n 
A 1 192 THR 192 701 701 THR THR A . n 
A 1 193 MET 193 702 702 MET MET A . n 
A 1 194 TYR 194 703 703 TYR TYR A . n 
A 1 195 ARG 195 704 704 ARG ARG A . n 
A 1 196 HIS 196 705 705 HIS HIS A . n 
A 1 197 MET 197 706 706 MET MET A . n 
A 1 198 GLU 198 707 707 GLU GLU A . n 
A 1 199 LYS 199 708 708 LYS LYS A . n 
A 1 200 HIS 200 709 709 HIS HIS A . n 
A 1 201 ASN 201 710 710 ASN ASN A . n 
A 1 202 TYR 202 711 711 TYR TYR A . n 
A 1 203 GLU 203 712 712 GLU GLU A . n 
A 1 204 SER 204 713 713 SER SER A . n 
A 1 205 ALA 205 714 714 ALA ALA A . n 
A 1 206 ALA 206 715 715 ALA ALA A . n 
A 1 207 GLU 207 716 716 GLU GLU A . n 
A 1 208 ALA 208 717 717 ALA ALA A . n 
A 1 209 ILE 209 718 718 ILE ILE A . n 
A 1 210 GLN 210 719 719 GLN GLN A . n 
A 1 211 ALA 211 720 720 ALA ALA A . n 
A 1 212 VAL 212 721 721 VAL VAL A . n 
A 1 213 ARG 213 722 722 ARG ARG A . n 
A 1 214 ASP 214 723 723 ASP ASP A . n 
A 1 215 ASN 215 724 724 ASN ASN A . n 
A 1 216 LYS 216 725 725 LYS LYS A . n 
A 1 217 LEU 217 726 726 LEU LEU A . n 
A 1 218 HIS 218 727 727 HIS HIS A . n 
A 1 219 ALA 219 728 728 ALA ALA A . n 
A 1 220 PHE 220 729 729 PHE PHE A . n 
A 1 221 ILE 221 730 730 ILE ILE A . n 
A 1 222 TRP 222 731 731 TRP TRP A . n 
A 1 223 ASP 223 732 732 ASP ASP A . n 
A 1 224 SER 224 733 733 SER SER A . n 
A 1 225 ALA 225 734 734 ALA ALA A . n 
A 1 226 VAL 226 735 735 VAL VAL A . n 
A 1 227 LEU 227 736 736 LEU LEU A . n 
A 1 228 GLU 228 737 737 GLU GLU A . n 
A 1 229 PHE 229 738 738 PHE PHE A . n 
A 1 230 GLU 230 739 739 GLU GLU A . n 
A 1 231 ALA 231 740 740 ALA ALA A . n 
A 1 232 SER 232 741 741 SER SER A . n 
A 1 233 GLN 233 742 742 GLN GLN A . n 
A 1 234 LYS 234 743 743 LYS LYS A . n 
A 1 235 CYS 235 744 744 CYS CYS A . n 
A 1 236 ASP 236 745 745 ASP ASP A . n 
A 1 237 LEU 237 746 746 LEU LEU A . n 
A 1 238 VAL 238 747 747 VAL VAL A . n 
A 1 239 THR 239 748 748 THR THR A . n 
A 1 240 THR 240 749 749 THR THR A . n 
A 1 241 GLY 241 750 750 GLY GLY A . n 
A 1 242 GLU 242 751 751 GLU GLU A . n 
A 1 243 LEU 243 752 752 LEU LEU A . n 
A 1 244 PHE 244 753 753 PHE PHE A . n 
A 1 245 PHE 245 754 754 PHE PHE A . n 
A 1 246 ARG 246 755 755 ARG ARG A . n 
A 1 247 SER 247 756 756 SER SER A . n 
A 1 248 GLY 248 757 757 GLY GLY A . n 
A 1 249 PHE 249 758 758 PHE PHE A . n 
A 1 250 GLY 250 759 759 GLY GLY A . n 
A 1 251 ILE 251 760 760 ILE ILE A . n 
A 1 252 GLY 252 761 761 GLY GLY A . n 
A 1 253 MET 253 762 762 MET MET A . n 
A 1 254 ARG 254 763 763 ARG ARG A . n 
A 1 255 LYS 255 764 764 LYS LYS A . n 
A 1 256 ASP 256 765 765 ASP ASP A . n 
A 1 257 SER 257 766 766 SER SER A . n 
A 1 258 PRO 258 767 767 PRO PRO A . n 
A 1 259 TRP 259 768 768 TRP TRP A . n 
A 1 260 LYS 260 769 769 LYS LYS A . n 
A 1 261 GLN 261 770 770 GLN GLN A . n 
A 1 262 ASN 262 771 771 ASN ASN A . n 
A 1 263 VAL 263 772 772 VAL VAL A . n 
A 1 264 SER 264 773 773 SER SER A . n 
A 1 265 LEU 265 774 774 LEU LEU A . n 
A 1 266 SER 266 775 775 SER SER A . n 
A 1 267 ILE 267 776 776 ILE ILE A . n 
A 1 268 LEU 268 777 777 LEU LEU A . n 
A 1 269 LYS 269 778 778 LYS LYS A . n 
A 1 270 SER 270 779 779 SER SER A . n 
A 1 271 HIS 271 780 780 HIS HIS A . n 
A 1 272 GLU 272 781 781 GLU GLU A . n 
A 1 273 ASN 273 782 782 ASN ASN A . n 
A 1 274 GLY 274 783 783 GLY GLY A . n 
A 1 275 PHE 275 784 784 PHE PHE A . n 
A 1 276 MET 276 785 785 MET MET A . n 
A 1 277 GLU 277 786 786 GLU GLU A . n 
A 1 278 ASP 278 787 787 ASP ASP A . n 
A 1 279 LEU 279 788 788 LEU LEU A . n 
A 1 280 ASP 280 789 789 ASP ASP A . n 
A 1 281 LYS 281 790 790 LYS LYS A . n 
A 1 282 THR 282 791 791 THR THR A . n 
A 1 283 TRP 283 792 792 TRP TRP A . n 
A 1 284 VAL 284 793 793 VAL VAL A . n 
A 1 285 ARG 285 794 794 ARG ARG A . n 
A 1 286 TYR 286 795 795 TYR TYR A . n 
A 1 287 GLN 287 796 796 GLN GLN A . n 
A 1 288 GLU 288 797 797 GLU GLU A . n 
A 1 289 CYS 289 798 798 CYS CYS A . n 
A 1 290 ASP 290 799 799 ASP ASP A . n 
A 1 291 SER 291 800 800 SER SER A . n 
A 1 292 ARG 292 801 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1ILR 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1ILR 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 A1ILR 1   901  1   A1ILR 288 A . 
C 3 SO4   1   902  1   SO4   SO4 A . 
D 4 HOH   1   1001 219 HOH   HOH A . 
D 4 HOH   2   1002 210 HOH   HOH A . 
D 4 HOH   3   1003 208 HOH   HOH A . 
D 4 HOH   4   1004 54  HOH   HOH A . 
D 4 HOH   5   1005 186 HOH   HOH A . 
D 4 HOH   6   1006 215 HOH   HOH A . 
D 4 HOH   7   1007 119 HOH   HOH A . 
D 4 HOH   8   1008 134 HOH   HOH A . 
D 4 HOH   9   1009 115 HOH   HOH A . 
D 4 HOH   10  1010 187 HOH   HOH A . 
D 4 HOH   11  1011 129 HOH   HOH A . 
D 4 HOH   12  1012 170 HOH   HOH A . 
D 4 HOH   13  1013 171 HOH   HOH A . 
D 4 HOH   14  1014 64  HOH   HOH A . 
D 4 HOH   15  1015 71  HOH   HOH A . 
D 4 HOH   16  1016 145 HOH   HOH A . 
D 4 HOH   17  1017 5   HOH   HOH A . 
D 4 HOH   18  1018 99  HOH   HOH A . 
D 4 HOH   19  1019 103 HOH   HOH A . 
D 4 HOH   20  1020 218 HOH   HOH A . 
D 4 HOH   21  1021 66  HOH   HOH A . 
D 4 HOH   22  1022 182 HOH   HOH A . 
D 4 HOH   23  1023 87  HOH   HOH A . 
D 4 HOH   24  1024 177 HOH   HOH A . 
D 4 HOH   25  1025 51  HOH   HOH A . 
D 4 HOH   26  1026 56  HOH   HOH A . 
D 4 HOH   27  1027 143 HOH   HOH A . 
D 4 HOH   28  1028 110 HOH   HOH A . 
D 4 HOH   29  1029 174 HOH   HOH A . 
D 4 HOH   30  1030 48  HOH   HOH A . 
D 4 HOH   31  1031 112 HOH   HOH A . 
D 4 HOH   32  1032 149 HOH   HOH A . 
D 4 HOH   33  1033 61  HOH   HOH A . 
D 4 HOH   34  1034 214 HOH   HOH A . 
D 4 HOH   35  1035 13  HOH   HOH A . 
D 4 HOH   36  1036 166 HOH   HOH A . 
D 4 HOH   37  1037 114 HOH   HOH A . 
D 4 HOH   38  1038 133 HOH   HOH A . 
D 4 HOH   39  1039 20  HOH   HOH A . 
D 4 HOH   40  1040 95  HOH   HOH A . 
D 4 HOH   41  1041 101 HOH   HOH A . 
D 4 HOH   42  1042 17  HOH   HOH A . 
D 4 HOH   43  1043 127 HOH   HOH A . 
D 4 HOH   44  1044 18  HOH   HOH A . 
D 4 HOH   45  1045 33  HOH   HOH A . 
D 4 HOH   46  1046 146 HOH   HOH A . 
D 4 HOH   47  1047 62  HOH   HOH A . 
D 4 HOH   48  1048 38  HOH   HOH A . 
D 4 HOH   49  1049 126 HOH   HOH A . 
D 4 HOH   50  1050 21  HOH   HOH A . 
D 4 HOH   51  1051 4   HOH   HOH A . 
D 4 HOH   52  1052 151 HOH   HOH A . 
D 4 HOH   53  1053 57  HOH   HOH A . 
D 4 HOH   54  1054 19  HOH   HOH A . 
D 4 HOH   55  1055 107 HOH   HOH A . 
D 4 HOH   56  1056 100 HOH   HOH A . 
D 4 HOH   57  1057 116 HOH   HOH A . 
D 4 HOH   58  1058 125 HOH   HOH A . 
D 4 HOH   59  1059 23  HOH   HOH A . 
D 4 HOH   60  1060 24  HOH   HOH A . 
D 4 HOH   61  1061 180 HOH   HOH A . 
D 4 HOH   62  1062 74  HOH   HOH A . 
D 4 HOH   63  1063 45  HOH   HOH A . 
D 4 HOH   64  1064 144 HOH   HOH A . 
D 4 HOH   65  1065 25  HOH   HOH A . 
D 4 HOH   66  1066 36  HOH   HOH A . 
D 4 HOH   67  1067 2   HOH   HOH A . 
D 4 HOH   68  1068 88  HOH   HOH A . 
D 4 HOH   69  1069 50  HOH   HOH A . 
D 4 HOH   70  1070 47  HOH   HOH A . 
D 4 HOH   71  1071 130 HOH   HOH A . 
D 4 HOH   72  1072 12  HOH   HOH A . 
D 4 HOH   73  1073 147 HOH   HOH A . 
D 4 HOH   74  1074 175 HOH   HOH A . 
D 4 HOH   75  1075 92  HOH   HOH A . 
D 4 HOH   76  1076 69  HOH   HOH A . 
D 4 HOH   77  1077 28  HOH   HOH A . 
D 4 HOH   78  1078 128 HOH   HOH A . 
D 4 HOH   79  1079 73  HOH   HOH A . 
D 4 HOH   80  1080 30  HOH   HOH A . 
D 4 HOH   81  1081 67  HOH   HOH A . 
D 4 HOH   82  1082 68  HOH   HOH A . 
D 4 HOH   83  1083 83  HOH   HOH A . 
D 4 HOH   84  1084 26  HOH   HOH A . 
D 4 HOH   85  1085 196 HOH   HOH A . 
D 4 HOH   86  1086 108 HOH   HOH A . 
D 4 HOH   87  1087 1   HOH   HOH A . 
D 4 HOH   88  1088 39  HOH   HOH A . 
D 4 HOH   89  1089 89  HOH   HOH A . 
D 4 HOH   90  1090 6   HOH   HOH A . 
D 4 HOH   91  1091 43  HOH   HOH A . 
D 4 HOH   92  1092 179 HOH   HOH A . 
D 4 HOH   93  1093 16  HOH   HOH A . 
D 4 HOH   94  1094 157 HOH   HOH A . 
D 4 HOH   95  1095 121 HOH   HOH A . 
D 4 HOH   96  1096 106 HOH   HOH A . 
D 4 HOH   97  1097 42  HOH   HOH A . 
D 4 HOH   98  1098 80  HOH   HOH A . 
D 4 HOH   99  1099 150 HOH   HOH A . 
D 4 HOH   100 1100 132 HOH   HOH A . 
D 4 HOH   101 1101 3   HOH   HOH A . 
D 4 HOH   102 1102 9   HOH   HOH A . 
D 4 HOH   103 1103 58  HOH   HOH A . 
D 4 HOH   104 1104 109 HOH   HOH A . 
D 4 HOH   105 1105 96  HOH   HOH A . 
D 4 HOH   106 1106 97  HOH   HOH A . 
D 4 HOH   107 1107 32  HOH   HOH A . 
D 4 HOH   108 1108 78  HOH   HOH A . 
D 4 HOH   109 1109 79  HOH   HOH A . 
D 4 HOH   110 1110 63  HOH   HOH A . 
D 4 HOH   111 1111 156 HOH   HOH A . 
D 4 HOH   112 1112 75  HOH   HOH A . 
D 4 HOH   113 1113 167 HOH   HOH A . 
D 4 HOH   114 1114 60  HOH   HOH A . 
D 4 HOH   115 1115 53  HOH   HOH A . 
D 4 HOH   116 1116 46  HOH   HOH A . 
D 4 HOH   117 1117 31  HOH   HOH A . 
D 4 HOH   118 1118 90  HOH   HOH A . 
D 4 HOH   119 1119 10  HOH   HOH A . 
D 4 HOH   120 1120 181 HOH   HOH A . 
D 4 HOH   121 1121 41  HOH   HOH A . 
D 4 HOH   122 1122 14  HOH   HOH A . 
D 4 HOH   123 1123 55  HOH   HOH A . 
D 4 HOH   124 1124 59  HOH   HOH A . 
D 4 HOH   125 1125 76  HOH   HOH A . 
D 4 HOH   126 1126 70  HOH   HOH A . 
D 4 HOH   127 1127 122 HOH   HOH A . 
D 4 HOH   128 1128 136 HOH   HOH A . 
D 4 HOH   129 1129 169 HOH   HOH A . 
D 4 HOH   130 1130 94  HOH   HOH A . 
D 4 HOH   131 1131 135 HOH   HOH A . 
D 4 HOH   132 1132 7   HOH   HOH A . 
D 4 HOH   133 1133 98  HOH   HOH A . 
D 4 HOH   134 1134 22  HOH   HOH A . 
D 4 HOH   135 1135 173 HOH   HOH A . 
D 4 HOH   136 1136 35  HOH   HOH A . 
D 4 HOH   137 1137 152 HOH   HOH A . 
D 4 HOH   138 1138 65  HOH   HOH A . 
D 4 HOH   139 1139 77  HOH   HOH A . 
D 4 HOH   140 1140 191 HOH   HOH A . 
D 4 HOH   141 1141 141 HOH   HOH A . 
D 4 HOH   142 1142 44  HOH   HOH A . 
D 4 HOH   143 1143 118 HOH   HOH A . 
D 4 HOH   144 1144 195 HOH   HOH A . 
D 4 HOH   145 1145 178 HOH   HOH A . 
D 4 HOH   146 1146 40  HOH   HOH A . 
D 4 HOH   147 1147 201 HOH   HOH A . 
D 4 HOH   148 1148 154 HOH   HOH A . 
D 4 HOH   149 1149 185 HOH   HOH A . 
D 4 HOH   150 1150 52  HOH   HOH A . 
D 4 HOH   151 1151 188 HOH   HOH A . 
D 4 HOH   152 1152 27  HOH   HOH A . 
D 4 HOH   153 1153 190 HOH   HOH A . 
D 4 HOH   154 1154 34  HOH   HOH A . 
D 4 HOH   155 1155 37  HOH   HOH A . 
D 4 HOH   156 1156 93  HOH   HOH A . 
D 4 HOH   157 1157 140 HOH   HOH A . 
D 4 HOH   158 1158 124 HOH   HOH A . 
D 4 HOH   159 1159 15  HOH   HOH A . 
D 4 HOH   160 1160 117 HOH   HOH A . 
D 4 HOH   161 1161 202 HOH   HOH A . 
D 4 HOH   162 1162 204 HOH   HOH A . 
D 4 HOH   163 1163 137 HOH   HOH A . 
D 4 HOH   164 1164 29  HOH   HOH A . 
D 4 HOH   165 1165 158 HOH   HOH A . 
D 4 HOH   166 1166 86  HOH   HOH A . 
D 4 HOH   167 1167 172 HOH   HOH A . 
D 4 HOH   168 1168 168 HOH   HOH A . 
D 4 HOH   169 1169 160 HOH   HOH A . 
D 4 HOH   170 1170 102 HOH   HOH A . 
D 4 HOH   171 1171 11  HOH   HOH A . 
D 4 HOH   172 1172 111 HOH   HOH A . 
D 4 HOH   173 1173 105 HOH   HOH A . 
D 4 HOH   174 1174 153 HOH   HOH A . 
D 4 HOH   175 1175 148 HOH   HOH A . 
D 4 HOH   176 1176 72  HOH   HOH A . 
D 4 HOH   177 1177 183 HOH   HOH A . 
D 4 HOH   178 1178 213 HOH   HOH A . 
D 4 HOH   179 1179 212 HOH   HOH A . 
D 4 HOH   180 1180 194 HOH   HOH A . 
D 4 HOH   181 1181 203 HOH   HOH A . 
D 4 HOH   182 1182 120 HOH   HOH A . 
D 4 HOH   183 1183 161 HOH   HOH A . 
D 4 HOH   184 1184 216 HOH   HOH A . 
D 4 HOH   185 1185 162 HOH   HOH A . 
D 4 HOH   186 1186 193 HOH   HOH A . 
D 4 HOH   187 1187 165 HOH   HOH A . 
D 4 HOH   188 1188 164 HOH   HOH A . 
D 4 HOH   189 1189 131 HOH   HOH A . 
D 4 HOH   190 1190 206 HOH   HOH A . 
D 4 HOH   191 1191 91  HOH   HOH A . 
D 4 HOH   192 1192 176 HOH   HOH A . 
D 4 HOH   193 1193 142 HOH   HOH A . 
D 4 HOH   194 1194 199 HOH   HOH A . 
D 4 HOH   195 1195 85  HOH   HOH A . 
D 4 HOH   196 1196 209 HOH   HOH A . 
D 4 HOH   197 1197 8   HOH   HOH A . 
D 4 HOH   198 1198 163 HOH   HOH A . 
D 4 HOH   199 1199 198 HOH   HOH A . 
D 4 HOH   200 1200 205 HOH   HOH A . 
D 4 HOH   201 1201 192 HOH   HOH A . 
D 4 HOH   202 1202 159 HOH   HOH A . 
D 4 HOH   203 1203 123 HOH   HOH A . 
D 4 HOH   204 1204 82  HOH   HOH A . 
D 4 HOH   205 1205 184 HOH   HOH A . 
D 4 HOH   206 1206 211 HOH   HOH A . 
D 4 HOH   207 1207 207 HOH   HOH A . 
D 4 HOH   208 1208 200 HOH   HOH A . 
D 4 HOH   209 1209 139 HOH   HOH A . 
D 4 HOH   210 1210 84  HOH   HOH A . 
D 4 HOH   211 1211 49  HOH   HOH A . 
D 4 HOH   212 1212 217 HOH   HOH A . 
D 4 HOH   213 1213 81  HOH   HOH A . 
D 4 HOH   214 1214 189 HOH   HOH A . 
D 4 HOH   215 1215 138 HOH   HOH A . 
D 4 HOH   216 1216 104 HOH   HOH A . 
D 4 HOH   217 1217 155 HOH   HOH A . 
D 4 HOH   218 1218 197 HOH   HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 448 ? CG  ? A ARG 55  CG  
2  1 Y 1 A ARG 448 ? CD  ? A ARG 55  CD  
3  1 Y 1 A ARG 448 ? NE  ? A ARG 55  NE  
4  1 Y 1 A ARG 448 ? CZ  ? A ARG 55  CZ  
5  1 Y 1 A ARG 448 ? NH1 ? A ARG 55  NH1 
6  1 Y 1 A ARG 448 ? NH2 ? A ARG 55  NH2 
7  1 Y 1 A ARG 468 ? CG  ? A ARG 75  CG  
8  1 Y 1 A ARG 468 ? CD  ? A ARG 75  CD  
9  1 Y 1 A ARG 468 ? NE  ? A ARG 75  NE  
10 1 Y 1 A ARG 468 ? CZ  ? A ARG 75  CZ  
11 1 Y 1 A ARG 468 ? NH1 ? A ARG 75  NH1 
12 1 Y 1 A ARG 468 ? NH2 ? A ARG 75  NH2 
13 1 Y 1 A LYS 495 ? CG  ? A LYS 102 CG  
14 1 Y 1 A LYS 495 ? CD  ? A LYS 102 CD  
15 1 Y 1 A LYS 495 ? CE  ? A LYS 102 CE  
16 1 Y 1 A LYS 495 ? NZ  ? A LYS 102 NZ  
17 1 Y 1 A ARG 663 ? CG  ? A ARG 154 CG  
18 1 Y 1 A ARG 663 ? CD  ? A ARG 154 CD  
19 1 Y 1 A ARG 663 ? NE  ? A ARG 154 NE  
20 1 Y 1 A ARG 663 ? CZ  ? A ARG 154 CZ  
21 1 Y 1 A ARG 663 ? NH1 ? A ARG 154 NH1 
22 1 Y 1 A ARG 663 ? NH2 ? A ARG 154 NH2 
23 1 Y 1 A ASP 677 ? CG  ? A ASP 168 CG  
24 1 Y 1 A ASP 677 ? OD1 ? A ASP 168 OD1 
25 1 Y 1 A ASP 677 ? OD2 ? A ASP 168 OD2 
26 1 Y 1 A LYS 678 ? CG  ? A LYS 169 CG  
27 1 Y 1 A LYS 678 ? CD  ? A LYS 169 CD  
28 1 Y 1 A LYS 678 ? CE  ? A LYS 169 CE  
29 1 Y 1 A LYS 678 ? NZ  ? A LYS 169 NZ  
30 1 Y 1 A ILE 691 ? CG1 ? A ILE 182 CG1 
31 1 Y 1 A ILE 691 ? CG2 ? A ILE 182 CG2 
32 1 Y 1 A ILE 691 ? CD1 ? A ILE 182 CD1 
33 1 Y 1 A ARG 694 ? CG  ? A ARG 185 CG  
34 1 Y 1 A ARG 694 ? CD  ? A ARG 185 CD  
35 1 Y 1 A ARG 694 ? NE  ? A ARG 185 NE  
36 1 Y 1 A ARG 694 ? CZ  ? A ARG 185 CZ  
37 1 Y 1 A ARG 694 ? NH1 ? A ARG 185 NH1 
38 1 Y 1 A ARG 694 ? NH2 ? A ARG 185 NH2 
39 1 Y 1 A ARG 695 ? CG  ? A ARG 186 CG  
40 1 Y 1 A ARG 695 ? CD  ? A ARG 186 CD  
41 1 Y 1 A ARG 695 ? NE  ? A ARG 186 NE  
42 1 Y 1 A ARG 695 ? CZ  ? A ARG 186 CZ  
43 1 Y 1 A ARG 695 ? NH1 ? A ARG 186 NH1 
44 1 Y 1 A ARG 695 ? NH2 ? A ARG 186 NH2 
45 1 Y 1 A GLN 696 ? CG  ? A GLN 187 CG  
46 1 Y 1 A GLN 696 ? CD  ? A GLN 187 CD  
47 1 Y 1 A GLN 696 ? OE1 ? A GLN 187 OE1 
48 1 Y 1 A GLN 696 ? NE2 ? A GLN 187 NE2 
49 1 Y 1 A VAL 697 ? CG1 ? A VAL 188 CG1 
50 1 Y 1 A VAL 697 ? CG2 ? A VAL 188 CG2 
51 1 Y 1 A GLU 698 ? CG  ? A GLU 189 CG  
52 1 Y 1 A GLU 698 ? CD  ? A GLU 189 CD  
53 1 Y 1 A GLU 698 ? OE1 ? A GLU 189 OE1 
54 1 Y 1 A GLU 698 ? OE2 ? A GLU 189 OE2 
55 1 Y 1 A ARG 704 ? CG  ? A ARG 195 CG  
56 1 Y 1 A ARG 704 ? CD  ? A ARG 195 CD  
57 1 Y 1 A ARG 704 ? NE  ? A ARG 195 NE  
58 1 Y 1 A ARG 704 ? CZ  ? A ARG 195 CZ  
59 1 Y 1 A ARG 704 ? NH1 ? A ARG 195 NH1 
60 1 Y 1 A ARG 704 ? NH2 ? A ARG 195 NH2 
61 1 Y 1 A GLU 707 ? CG  ? A GLU 198 CG  
62 1 Y 1 A GLU 707 ? CD  ? A GLU 198 CD  
63 1 Y 1 A GLU 707 ? OE1 ? A GLU 198 OE1 
64 1 Y 1 A GLU 707 ? OE2 ? A GLU 198 OE2 
65 1 Y 1 A LYS 708 ? CG  ? A LYS 199 CG  
66 1 Y 1 A LYS 708 ? CD  ? A LYS 199 CD  
67 1 Y 1 A LYS 708 ? CE  ? A LYS 199 CE  
68 1 Y 1 A LYS 708 ? NZ  ? A LYS 199 NZ  
69 1 Y 1 A LYS 725 ? CG  ? A LYS 216 CG  
70 1 Y 1 A LYS 725 ? CD  ? A LYS 216 CD  
71 1 Y 1 A LYS 725 ? CE  ? A LYS 216 CE  
72 1 Y 1 A LYS 725 ? NZ  ? A LYS 216 NZ  
73 1 Y 1 A GLU 751 ? CG  ? A GLU 242 CG  
74 1 Y 1 A GLU 751 ? CD  ? A GLU 242 CD  
75 1 Y 1 A GLU 751 ? OE1 ? A GLU 242 OE1 
76 1 Y 1 A GLU 751 ? OE2 ? A GLU 242 OE2 
77 1 Y 1 A GLN 770 ? CG  ? A GLN 261 CG  
78 1 Y 1 A GLN 770 ? CD  ? A GLN 261 CD  
79 1 Y 1 A GLN 770 ? OE1 ? A GLN 261 OE1 
80 1 Y 1 A GLN 770 ? NE2 ? A GLN 261 NE2 
81 1 Y 1 A LYS 778 ? CG  ? A LYS 269 CG  
82 1 Y 1 A LYS 778 ? CD  ? A LYS 269 CD  
83 1 Y 1 A LYS 778 ? CE  ? A LYS 269 CE  
84 1 Y 1 A LYS 778 ? NZ  ? A LYS 269 NZ  
85 1 Y 1 A LYS 790 ? NZ  ? A LYS 281 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? '5.8.0430 (refmacat 0.4.82)' 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? MOSFLM  ? ? ? .                            2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .                            3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .                            4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GIF 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     41.85 
_cell.length_a_esd                 ? 
_cell.length_b                     71.53 
_cell.length_b_esd                 ? 
_cell.length_c                     96.3 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GIF 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GIF 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.18 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          43.59 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              5.7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '20% (w/v) PEG 3350, 0.1 M Bis-Tris pH 5.7 and 0.2 M lithium sulfate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            282.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'RIGAKU SATURN 944' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2015-09-15 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.54 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      'ROTATING ANODE' 
_diffrn_source.target                      ? 
_diffrn_source.type                        'RIGAKU MICROMAX-007 HF' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.54 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ? 
_diffrn_source.pdbx_synchrotron_site       ? 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9GIF 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.90 
_reflns.d_resolution_low                               23.16 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     21502 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           92.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          11.2 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.995 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.071 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.90 
_reflns_shell.d_res_low                                     1.94 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           3.3 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             948 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.853 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.285 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.317 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            0.817 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            -0.500 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               21.419 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.945 
_refine.correlation_coeff_Fo_to_Fc_free          0.925 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9GIF 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.900 
_refine.ls_d_res_low                             23.155 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     21474 
_refine.ls_number_reflns_R_free                  1040 
_refine.ls_number_reflns_R_work                  20434 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    91.445 
_refine.ls_percent_reflns_R_free                 4.843 
_refine.ls_R_factor_all                          0.179 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2145 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1773 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      0.213 
_refine.ls_wR_factor_R_work                      0.175 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.171 
_refine.pdbx_overall_ESU_R_Free                  0.149 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             3.166 
_refine.overall_SU_ML                            0.093 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    0.9798 
_refine.pdbx_average_fsc_free                    0.9709 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.900 
_refine_hist.d_res_low                        23.155 
_refine_hist.number_atoms_solvent             218 
_refine_hist.number_atoms_total               2463 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2226 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         19 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  2311 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  2077 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.549  1.820  3141 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.545  1.761  4805 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.933  5.000  290  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 6.304  5.000  9    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.456 10.000 375  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.774 10.000 103  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.071  0.200  348  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  2726 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  531  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.223  0.200  431  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.181  0.200  1974 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.179  0.200  1160 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.087  0.200  1222 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.160  0.200  158  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.216  0.200  24   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.234  0.200  65   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.120  0.200  16   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.096  2.053  1155 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.096  2.053  1155 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 3.312  3.685  1443 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.314  3.687  1444 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 2.582  2.280  1156 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.584  2.281  1152 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 4.223  4.084  1696 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 4.229  4.085  1691 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 7.268  25.001 9691 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 7.187  24.783 9481 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.900 1.949  1672 . 59 990  62.7392 . 0.233 . . 0.234 . . . . . 0.219 . 20 . 0.969 0.972 0.217 
'X-RAY DIFFRACTION' 1.949 2.002  1676 . 62 1236 77.4463 . 0.202 . . 0.201 . . . . . 0.180 . 20 . 0.974 0.975 0.216 
'X-RAY DIFFRACTION' 2.002 2.060  1600 . 87 1427 94.6250 . 0.191 . . 0.188 . . . . . 0.165 . 20 . 0.976 0.965 0.229 
'X-RAY DIFFRACTION' 2.060 2.123  1566 . 61 1393 92.8480 . 0.168 . . 0.168 . . . . . 0.149 . 20 . 0.981 0.979 0.179 
'X-RAY DIFFRACTION' 2.123 2.192  1540 . 74 1367 93.5714 . 0.174 . . 0.170 . . . . . 0.155 . 20 . 0.980 0.960 0.251 
'X-RAY DIFFRACTION' 2.192 2.268  1431 . 68 1279 94.1300 . 0.168 . . 0.167 . . . . . 0.151 . 20 . 0.981 0.974 0.187 
'X-RAY DIFFRACTION' 2.268 2.352  1443 . 71 1305 95.3569 . 0.159 . . 0.157 . . . . . 0.140 . 20 . 0.984 0.975 0.204 
'X-RAY DIFFRACTION' 2.352 2.448  1386 . 53 1258 94.5887 . 0.164 . . 0.161 . . . . . 0.148 . 20 . 0.983 0.965 0.230 
'X-RAY DIFFRACTION' 2.448 2.555  1308 . 57 1199 96.0245 . 0.169 . . 0.166 . . . . . 0.152 . 20 . 0.982 0.973 0.222 
'X-RAY DIFFRACTION' 2.555 2.678  1263 . 45 1110 91.4489 . 0.162 . . 0.160 . . . . . 0.150 . 20 . 0.983 0.971 0.212 
'X-RAY DIFFRACTION' 2.678 2.821  1206 . 63 1069 93.8640 . 0.164 . . 0.162 . . . . . 0.149 . 20 . 0.983 0.973 0.198 
'X-RAY DIFFRACTION' 2.821 2.989  1159 . 52 1064 96.2899 . 0.175 . . 0.174 . . . . . 0.165 . 20 . 0.981 0.967 0.215 
'X-RAY DIFFRACTION' 2.989 3.192  1078 . 54 999  97.6809 . 0.174 . . 0.171 . . . . . 0.167 . 20 . 0.981 0.967 0.223 
'X-RAY DIFFRACTION' 3.192 3.442  1020 . 54 947  98.1373 . 0.190 . . 0.188 . . . . . 0.189 . 20 . 0.979 0.964 0.223 
'X-RAY DIFFRACTION' 3.442 3.762  942  . 35 882  97.3461 . 0.184 . . 0.181 . . . . . 0.187 . 20 . 0.979 0.969 0.243 
'X-RAY DIFFRACTION' 3.762 4.193  860  . 34 796  96.5116 . 0.157 . . 0.157 . . . . . 0.167 . 20 . 0.985 0.987 0.163 
'X-RAY DIFFRACTION' 4.193 4.815  764  . 40 682  94.5026 . 0.150 . . 0.149 . . . . . 0.163 . 20 . 0.987 0.985 0.169 
'X-RAY DIFFRACTION' 4.815 5.834  658  . 30 609  97.1125 . 0.217 . . 0.215 . . . . . 0.234 . 20 . 0.977 0.973 0.251 
'X-RAY DIFFRACTION' 5.834 8.001  542  . 22 510  98.1550 . 0.247 . . 0.244 . . . . . 0.255 . 20 . 0.970 0.966 0.313 
'X-RAY DIFFRACTION' 8.001 23.155 350  . 19 312  94.5714 . 0.240 . . 0.240 . . . . . 0.277 . 20 . 0.968 0.961 0.239 
# 
_struct.entry_id                     9GIF 
_struct.title                        'NMDA bound to compound 288' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GIF 
_struct_keywords.text            'ion transport ligand gated ion channel, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP NMDZ1_HUMAN Q05586 ? 1 
;MSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFT
YEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK
;
394 
2 UNP NMDZ1_HUMAN Q05586 ? 1 
;RITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQ
KCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSR
;
663 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9GIF A 1   ? 151 ? Q05586 394 ? 544 ? 394 544 
2 2 9GIF A 154 ? 292 ? Q05586 663 ? 801 ? 663 801 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9GIF GLY A 152 ? UNP Q05586 ? ? linker 545 1 
1 9GIF THR A 153 ? UNP Q05586 ? ? linker 546 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 190   ? 
1 MORE         -12   ? 
1 'SSA (A^2)'  13720 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 64  ? ASN A 78  ? GLY A 457 ASN A 471 1 ? 15 
HELX_P HELX_P2  AA2 ASN A 106 ? SER A 114 ? ASN A 499 SER A 507 1 ? 9  
HELX_P HELX_P3  AA3 ASN A 127 ? GLN A 132 ? ASN A 520 GLN A 525 1 ? 6  
HELX_P HELX_P4  AA4 ASP A 160 ? ASN A 165 ? ASP A 669 ASN A 674 1 ? 6  
HELX_P HELX_P5  AA5 SER A 179 ? ARG A 186 ? SER A 688 ARG A 695 1 ? 8  
HELX_P HELX_P6  AA6 LEU A 190 ? LYS A 199 ? LEU A 699 LYS A 708 1 ? 10 
HELX_P HELX_P7  AA7 SER A 204 ? ASP A 214 ? SER A 713 ASP A 723 1 ? 11 
HELX_P HELX_P8  AA8 SER A 224 ? LYS A 234 ? SER A 733 LYS A 743 1 ? 11 
HELX_P HELX_P9  AA9 TRP A 259 ? ASN A 273 ? TRP A 768 ASN A 782 1 ? 15 
HELX_P HELX_P10 AB1 GLY A 274 ? VAL A 284 ? GLY A 783 VAL A 793 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 27  SG ? ? ? 1_555 A CYS 61  SG ? ? A CYS 420 A CYS 454 1_555 ? ? ? ? ? ? ? 2.004 ? ? 
disulf2 disulf ? ? A CYS 43  SG ? ? ? 1_555 A CYS 62  SG ? ? A CYS 436 A CYS 455 1_555 ? ? ? ? ? ? ? 2.117 ? ? 
disulf3 disulf ? ? A CYS 235 SG ? ? ? 1_555 A CYS 289 SG ? ? A CYS 744 A CYS 798 1_555 ? ? ? ? ? ? ? 2.024 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 27  ? CYS A 61  ? CYS A 420 ? 1_555 CYS A 454 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 43  ? CYS A 62  ? CYS A 436 ? 1_555 CYS A 455 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS A 235 ? CYS A 289 ? CYS A 744 ? 1_555 CYS A 798 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLU 
_struct_mon_prot_cis.label_seq_id           13 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLU 
_struct_mon_prot_cis.auth_seq_id            406 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    14 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     407 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       2.36 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TYR A 17  ? PRO A 20  ? TYR A 410 PRO A 413 
AA1 2 THR A 57  ? TYR A 63  ? THR A 450 TYR A 456 
AA1 3 VAL A 41  ? PRO A 46  ? VAL A 434 PRO A 439 
AA1 4 TYR A 81  ? LEU A 85  ? TYR A 474 LEU A 478 
AA1 5 LEU A 5   ? THR A 9   ? LEU A 398 THR A 402 
AA1 6 MET A 119 ? ILE A 120 ? MET A 512 ILE A 513 
AA2 1 GLN A 94  ? ARG A 96  ? GLN A 487 ARG A 489 
AA2 2 LYS A 103 ? TRP A 105 ? LYS A 496 TRP A 498 
AA3 1 ILE A 134 ? PHE A 136 ? ILE A 527 PHE A 529 
AA3 2 GLY A 252 ? ARG A 254 ? GLY A 761 ARG A 763 
AA4 1 TYR A 172 ? ALA A 173 ? TYR A 681 ALA A 682 
AA4 2 ALA A 219 ? ASP A 223 ? ALA A 728 ASP A 732 
AA4 3 LYS A 141 ? LYS A 150 ? LYS A 534 LYS A 543 
AA4 4 LEU A 237 ? PHE A 249 ? LEU A 746 PHE A 758 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N TYR A 17  ? N TYR A 410 O TYR A 63  ? O TYR A 456 
AA1 2 3 O VAL A 58  ? O VAL A 451 N GLY A 45  ? N GLY A 438 
AA1 3 4 N THR A 44  ? N THR A 437 O LEU A 85  ? O LEU A 478 
AA1 4 5 O GLU A 82  ? O GLU A 475 N ILE A 7   ? N ILE A 400 
AA1 5 6 N VAL A 8   ? N VAL A 401 O MET A 119 ? O MET A 512 
AA2 1 2 N GLU A 95  ? N GLU A 488 O GLU A 104 ? O GLU A 497 
AA3 1 2 N GLU A 135 ? N GLU A 528 O MET A 253 ? O MET A 762 
AA4 1 2 N ALA A 173 ? N ALA A 682 O ILE A 221 ? O ILE A 730 
AA4 2 3 O PHE A 220 ? O PHE A 729 N LEU A 148 ? N LEU A 541 
AA4 3 4 N LEU A 145 ? N LEU A 538 O PHE A 244 ? O PHE A 753 
# 
_pdbx_entry_details.entry_id                   9GIF 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 HB3 A LYS 778 ? ? O A HOH 1174 ? ? 1.28 
2 1 HG1 A THR 683 ? ? H A VAL 684  ? ? 1.28 
3 1 CB  A LYS 778 ? ? O A HOH 1174 ? ? 1.60 
4 1 OG  A SER 800 ? ? O A HOH 1001 ? ? 1.94 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLN A 405 ? ? -172.14 90.60   
2 1 GLN A 536 ? ? -155.22 -158.86 
3 1 THR A 683 ? ? -129.33 -160.27 
4 1 TYR A 795 ? ? -150.71 -17.61  
5 1 ASP A 799 ? ? -145.06 21.91   
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A MET 394 ? A MET 1   
2 1 Y 1 A SER 395 ? A SER 2   
3 1 Y 1 A THR 396 ? A THR 3   
4 1 Y 1 A ARG 801 ? A ARG 292 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1ILR C1   C N N 1   
A1ILR C2   C N N 2   
A1ILR C3   C N N 3   
A1ILR C4   C N N 4   
A1ILR C8   C N N 5   
A1ILR C9   C N R 6   
A1ILR O13  O N N 7   
A1ILR C5   C N N 8   
A1ILR S6   S N N 9   
A1ILR N7   N N N 10  
A1ILR N10  N N N 11  
A1ILR C11  C N N 12  
A1ILR O12  O N N 13  
A1ILR O14  O N N 14  
A1ILR H3   H N N 15  
A1ILR H4   H N N 16  
A1ILR H81  H N N 17  
A1ILR H8   H N N 18  
A1ILR H9   H N N 19  
A1ILR H1   H N N 20  
A1ILR H5   H N N 21  
A1ILR HN7  H N N 22  
A1ILR HN10 H N N 23  
A1ILR HN11 H N N 24  
A1ILR H2   H N N 25  
A1ILR H6   H N N 26  
ALA   N    N N N 27  
ALA   CA   C N S 28  
ALA   C    C N N 29  
ALA   O    O N N 30  
ALA   CB   C N N 31  
ALA   OXT  O N N 32  
ALA   H    H N N 33  
ALA   H2   H N N 34  
ALA   HA   H N N 35  
ALA   HB1  H N N 36  
ALA   HB2  H N N 37  
ALA   HB3  H N N 38  
ALA   HXT  H N N 39  
ARG   N    N N N 40  
ARG   CA   C N S 41  
ARG   C    C N N 42  
ARG   O    O N N 43  
ARG   CB   C N N 44  
ARG   CG   C N N 45  
ARG   CD   C N N 46  
ARG   NE   N N N 47  
ARG   CZ   C N N 48  
ARG   NH1  N N N 49  
ARG   NH2  N N N 50  
ARG   OXT  O N N 51  
ARG   H    H N N 52  
ARG   H2   H N N 53  
ARG   HA   H N N 54  
ARG   HB2  H N N 55  
ARG   HB3  H N N 56  
ARG   HG2  H N N 57  
ARG   HG3  H N N 58  
ARG   HD2  H N N 59  
ARG   HD3  H N N 60  
ARG   HE   H N N 61  
ARG   HH11 H N N 62  
ARG   HH12 H N N 63  
ARG   HH21 H N N 64  
ARG   HH22 H N N 65  
ARG   HXT  H N N 66  
ASN   N    N N N 67  
ASN   CA   C N S 68  
ASN   C    C N N 69  
ASN   O    O N N 70  
ASN   CB   C N N 71  
ASN   CG   C N N 72  
ASN   OD1  O N N 73  
ASN   ND2  N N N 74  
ASN   OXT  O N N 75  
ASN   H    H N N 76  
ASN   H2   H N N 77  
ASN   HA   H N N 78  
ASN   HB2  H N N 79  
ASN   HB3  H N N 80  
ASN   HD21 H N N 81  
ASN   HD22 H N N 82  
ASN   HXT  H N N 83  
ASP   N    N N N 84  
ASP   CA   C N S 85  
ASP   C    C N N 86  
ASP   O    O N N 87  
ASP   CB   C N N 88  
ASP   CG   C N N 89  
ASP   OD1  O N N 90  
ASP   OD2  O N N 91  
ASP   OXT  O N N 92  
ASP   H    H N N 93  
ASP   H2   H N N 94  
ASP   HA   H N N 95  
ASP   HB2  H N N 96  
ASP   HB3  H N N 97  
ASP   HD2  H N N 98  
ASP   HXT  H N N 99  
CYS   N    N N N 100 
CYS   CA   C N R 101 
CYS   C    C N N 102 
CYS   O    O N N 103 
CYS   CB   C N N 104 
CYS   SG   S N N 105 
CYS   OXT  O N N 106 
CYS   H    H N N 107 
CYS   H2   H N N 108 
CYS   HA   H N N 109 
CYS   HB2  H N N 110 
CYS   HB3  H N N 111 
CYS   HG   H N N 112 
CYS   HXT  H N N 113 
GLN   N    N N N 114 
GLN   CA   C N S 115 
GLN   C    C N N 116 
GLN   O    O N N 117 
GLN   CB   C N N 118 
GLN   CG   C N N 119 
GLN   CD   C N N 120 
GLN   OE1  O N N 121 
GLN   NE2  N N N 122 
GLN   OXT  O N N 123 
GLN   H    H N N 124 
GLN   H2   H N N 125 
GLN   HA   H N N 126 
GLN   HB2  H N N 127 
GLN   HB3  H N N 128 
GLN   HG2  H N N 129 
GLN   HG3  H N N 130 
GLN   HE21 H N N 131 
GLN   HE22 H N N 132 
GLN   HXT  H N N 133 
GLU   N    N N N 134 
GLU   CA   C N S 135 
GLU   C    C N N 136 
GLU   O    O N N 137 
GLU   CB   C N N 138 
GLU   CG   C N N 139 
GLU   CD   C N N 140 
GLU   OE1  O N N 141 
GLU   OE2  O N N 142 
GLU   OXT  O N N 143 
GLU   H    H N N 144 
GLU   H2   H N N 145 
GLU   HA   H N N 146 
GLU   HB2  H N N 147 
GLU   HB3  H N N 148 
GLU   HG2  H N N 149 
GLU   HG3  H N N 150 
GLU   HE2  H N N 151 
GLU   HXT  H N N 152 
GLY   N    N N N 153 
GLY   CA   C N N 154 
GLY   C    C N N 155 
GLY   O    O N N 156 
GLY   OXT  O N N 157 
GLY   H    H N N 158 
GLY   H2   H N N 159 
GLY   HA2  H N N 160 
GLY   HA3  H N N 161 
GLY   HXT  H N N 162 
HIS   N    N N N 163 
HIS   CA   C N S 164 
HIS   C    C N N 165 
HIS   O    O N N 166 
HIS   CB   C N N 167 
HIS   CG   C Y N 168 
HIS   ND1  N Y N 169 
HIS   CD2  C Y N 170 
HIS   CE1  C Y N 171 
HIS   NE2  N Y N 172 
HIS   OXT  O N N 173 
HIS   H    H N N 174 
HIS   H2   H N N 175 
HIS   HA   H N N 176 
HIS   HB2  H N N 177 
HIS   HB3  H N N 178 
HIS   HD1  H N N 179 
HIS   HD2  H N N 180 
HIS   HE1  H N N 181 
HIS   HE2  H N N 182 
HIS   HXT  H N N 183 
HOH   O    O N N 184 
HOH   H1   H N N 185 
HOH   H2   H N N 186 
ILE   N    N N N 187 
ILE   CA   C N S 188 
ILE   C    C N N 189 
ILE   O    O N N 190 
ILE   CB   C N S 191 
ILE   CG1  C N N 192 
ILE   CG2  C N N 193 
ILE   CD1  C N N 194 
ILE   OXT  O N N 195 
ILE   H    H N N 196 
ILE   H2   H N N 197 
ILE   HA   H N N 198 
ILE   HB   H N N 199 
ILE   HG12 H N N 200 
ILE   HG13 H N N 201 
ILE   HG21 H N N 202 
ILE   HG22 H N N 203 
ILE   HG23 H N N 204 
ILE   HD11 H N N 205 
ILE   HD12 H N N 206 
ILE   HD13 H N N 207 
ILE   HXT  H N N 208 
LEU   N    N N N 209 
LEU   CA   C N S 210 
LEU   C    C N N 211 
LEU   O    O N N 212 
LEU   CB   C N N 213 
LEU   CG   C N N 214 
LEU   CD1  C N N 215 
LEU   CD2  C N N 216 
LEU   OXT  O N N 217 
LEU   H    H N N 218 
LEU   H2   H N N 219 
LEU   HA   H N N 220 
LEU   HB2  H N N 221 
LEU   HB3  H N N 222 
LEU   HG   H N N 223 
LEU   HD11 H N N 224 
LEU   HD12 H N N 225 
LEU   HD13 H N N 226 
LEU   HD21 H N N 227 
LEU   HD22 H N N 228 
LEU   HD23 H N N 229 
LEU   HXT  H N N 230 
LYS   N    N N N 231 
LYS   CA   C N S 232 
LYS   C    C N N 233 
LYS   O    O N N 234 
LYS   CB   C N N 235 
LYS   CG   C N N 236 
LYS   CD   C N N 237 
LYS   CE   C N N 238 
LYS   NZ   N N N 239 
LYS   OXT  O N N 240 
LYS   H    H N N 241 
LYS   H2   H N N 242 
LYS   HA   H N N 243 
LYS   HB2  H N N 244 
LYS   HB3  H N N 245 
LYS   HG2  H N N 246 
LYS   HG3  H N N 247 
LYS   HD2  H N N 248 
LYS   HD3  H N N 249 
LYS   HE2  H N N 250 
LYS   HE3  H N N 251 
LYS   HZ1  H N N 252 
LYS   HZ2  H N N 253 
LYS   HZ3  H N N 254 
LYS   HXT  H N N 255 
MET   N    N N N 256 
MET   CA   C N S 257 
MET   C    C N N 258 
MET   O    O N N 259 
MET   CB   C N N 260 
MET   CG   C N N 261 
MET   SD   S N N 262 
MET   CE   C N N 263 
MET   OXT  O N N 264 
MET   H    H N N 265 
MET   H2   H N N 266 
MET   HA   H N N 267 
MET   HB2  H N N 268 
MET   HB3  H N N 269 
MET   HG2  H N N 270 
MET   HG3  H N N 271 
MET   HE1  H N N 272 
MET   HE2  H N N 273 
MET   HE3  H N N 274 
MET   HXT  H N N 275 
PHE   N    N N N 276 
PHE   CA   C N S 277 
PHE   C    C N N 278 
PHE   O    O N N 279 
PHE   CB   C N N 280 
PHE   CG   C Y N 281 
PHE   CD1  C Y N 282 
PHE   CD2  C Y N 283 
PHE   CE1  C Y N 284 
PHE   CE2  C Y N 285 
PHE   CZ   C Y N 286 
PHE   OXT  O N N 287 
PHE   H    H N N 288 
PHE   H2   H N N 289 
PHE   HA   H N N 290 
PHE   HB2  H N N 291 
PHE   HB3  H N N 292 
PHE   HD1  H N N 293 
PHE   HD2  H N N 294 
PHE   HE1  H N N 295 
PHE   HE2  H N N 296 
PHE   HZ   H N N 297 
PHE   HXT  H N N 298 
PRO   N    N N N 299 
PRO   CA   C N S 300 
PRO   C    C N N 301 
PRO   O    O N N 302 
PRO   CB   C N N 303 
PRO   CG   C N N 304 
PRO   CD   C N N 305 
PRO   OXT  O N N 306 
PRO   H    H N N 307 
PRO   HA   H N N 308 
PRO   HB2  H N N 309 
PRO   HB3  H N N 310 
PRO   HG2  H N N 311 
PRO   HG3  H N N 312 
PRO   HD2  H N N 313 
PRO   HD3  H N N 314 
PRO   HXT  H N N 315 
SER   N    N N N 316 
SER   CA   C N S 317 
SER   C    C N N 318 
SER   O    O N N 319 
SER   CB   C N N 320 
SER   OG   O N N 321 
SER   OXT  O N N 322 
SER   H    H N N 323 
SER   H2   H N N 324 
SER   HA   H N N 325 
SER   HB2  H N N 326 
SER   HB3  H N N 327 
SER   HG   H N N 328 
SER   HXT  H N N 329 
SO4   S    S N N 330 
SO4   O1   O N N 331 
SO4   O2   O N N 332 
SO4   O3   O N N 333 
SO4   O4   O N N 334 
THR   N    N N N 335 
THR   CA   C N S 336 
THR   C    C N N 337 
THR   O    O N N 338 
THR   CB   C N R 339 
THR   OG1  O N N 340 
THR   CG2  C N N 341 
THR   OXT  O N N 342 
THR   H    H N N 343 
THR   H2   H N N 344 
THR   HA   H N N 345 
THR   HB   H N N 346 
THR   HG1  H N N 347 
THR   HG21 H N N 348 
THR   HG22 H N N 349 
THR   HG23 H N N 350 
THR   HXT  H N N 351 
TRP   N    N N N 352 
TRP   CA   C N S 353 
TRP   C    C N N 354 
TRP   O    O N N 355 
TRP   CB   C N N 356 
TRP   CG   C Y N 357 
TRP   CD1  C Y N 358 
TRP   CD2  C Y N 359 
TRP   NE1  N Y N 360 
TRP   CE2  C Y N 361 
TRP   CE3  C Y N 362 
TRP   CZ2  C Y N 363 
TRP   CZ3  C Y N 364 
TRP   CH2  C Y N 365 
TRP   OXT  O N N 366 
TRP   H    H N N 367 
TRP   H2   H N N 368 
TRP   HA   H N N 369 
TRP   HB2  H N N 370 
TRP   HB3  H N N 371 
TRP   HD1  H N N 372 
TRP   HE1  H N N 373 
TRP   HE3  H N N 374 
TRP   HZ2  H N N 375 
TRP   HZ3  H N N 376 
TRP   HH2  H N N 377 
TRP   HXT  H N N 378 
TYR   N    N N N 379 
TYR   CA   C N S 380 
TYR   C    C N N 381 
TYR   O    O N N 382 
TYR   CB   C N N 383 
TYR   CG   C Y N 384 
TYR   CD1  C Y N 385 
TYR   CD2  C Y N 386 
TYR   CE1  C Y N 387 
TYR   CE2  C Y N 388 
TYR   CZ   C Y N 389 
TYR   OH   O N N 390 
TYR   OXT  O N N 391 
TYR   H    H N N 392 
TYR   H2   H N N 393 
TYR   HA   H N N 394 
TYR   HB2  H N N 395 
TYR   HB3  H N N 396 
TYR   HD1  H N N 397 
TYR   HD2  H N N 398 
TYR   HE1  H N N 399 
TYR   HE2  H N N 400 
TYR   HH   H N N 401 
TYR   HXT  H N N 402 
VAL   N    N N N 403 
VAL   CA   C N S 404 
VAL   C    C N N 405 
VAL   O    O N N 406 
VAL   CB   C N N 407 
VAL   CG1  C N N 408 
VAL   CG2  C N N 409 
VAL   OXT  O N N 410 
VAL   H    H N N 411 
VAL   H2   H N N 412 
VAL   HA   H N N 413 
VAL   HB   H N N 414 
VAL   HG11 H N N 415 
VAL   HG12 H N N 416 
VAL   HG13 H N N 417 
VAL   HG21 H N N 418 
VAL   HG22 H N N 419 
VAL   HG23 H N N 420 
VAL   HXT  H N N 421 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1ILR O13 C11  doub N N 1   
A1ILR O12 C11  sing N N 2   
A1ILR C11 C9   sing N N 3   
A1ILR C9  N10  sing N N 4   
A1ILR C9  C8   sing N N 5   
A1ILR C8  N7   sing N N 6   
A1ILR O14 C1   doub N N 7   
A1ILR N7  C1   sing N N 8   
A1ILR C1  C2   sing N N 9   
A1ILR C2  S6   doub N N 10  
A1ILR C2  C3   sing N N 11  
A1ILR S6  C5   sing N N 12  
A1ILR C3  C4   doub N N 13  
A1ILR C4  C5   sing N N 14  
A1ILR C3  H3   sing N N 15  
A1ILR C4  H4   sing N N 16  
A1ILR C8  H81  sing N N 17  
A1ILR C8  H8   sing N N 18  
A1ILR C9  H9   sing N N 19  
A1ILR C5  H1   sing N N 20  
A1ILR C5  H5   sing N N 21  
A1ILR N7  HN7  sing N N 22  
A1ILR N10 HN10 sing N N 23  
A1ILR N10 HN11 sing N N 24  
A1ILR O12 H2   sing N N 25  
A1ILR S6  H6   sing N N 26  
ALA   N   CA   sing N N 27  
ALA   N   H    sing N N 28  
ALA   N   H2   sing N N 29  
ALA   CA  C    sing N N 30  
ALA   CA  CB   sing N N 31  
ALA   CA  HA   sing N N 32  
ALA   C   O    doub N N 33  
ALA   C   OXT  sing N N 34  
ALA   CB  HB1  sing N N 35  
ALA   CB  HB2  sing N N 36  
ALA   CB  HB3  sing N N 37  
ALA   OXT HXT  sing N N 38  
ARG   N   CA   sing N N 39  
ARG   N   H    sing N N 40  
ARG   N   H2   sing N N 41  
ARG   CA  C    sing N N 42  
ARG   CA  CB   sing N N 43  
ARG   CA  HA   sing N N 44  
ARG   C   O    doub N N 45  
ARG   C   OXT  sing N N 46  
ARG   CB  CG   sing N N 47  
ARG   CB  HB2  sing N N 48  
ARG   CB  HB3  sing N N 49  
ARG   CG  CD   sing N N 50  
ARG   CG  HG2  sing N N 51  
ARG   CG  HG3  sing N N 52  
ARG   CD  NE   sing N N 53  
ARG   CD  HD2  sing N N 54  
ARG   CD  HD3  sing N N 55  
ARG   NE  CZ   sing N N 56  
ARG   NE  HE   sing N N 57  
ARG   CZ  NH1  sing N N 58  
ARG   CZ  NH2  doub N N 59  
ARG   NH1 HH11 sing N N 60  
ARG   NH1 HH12 sing N N 61  
ARG   NH2 HH21 sing N N 62  
ARG   NH2 HH22 sing N N 63  
ARG   OXT HXT  sing N N 64  
ASN   N   CA   sing N N 65  
ASN   N   H    sing N N 66  
ASN   N   H2   sing N N 67  
ASN   CA  C    sing N N 68  
ASN   CA  CB   sing N N 69  
ASN   CA  HA   sing N N 70  
ASN   C   O    doub N N 71  
ASN   C   OXT  sing N N 72  
ASN   CB  CG   sing N N 73  
ASN   CB  HB2  sing N N 74  
ASN   CB  HB3  sing N N 75  
ASN   CG  OD1  doub N N 76  
ASN   CG  ND2  sing N N 77  
ASN   ND2 HD21 sing N N 78  
ASN   ND2 HD22 sing N N 79  
ASN   OXT HXT  sing N N 80  
ASP   N   CA   sing N N 81  
ASP   N   H    sing N N 82  
ASP   N   H2   sing N N 83  
ASP   CA  C    sing N N 84  
ASP   CA  CB   sing N N 85  
ASP   CA  HA   sing N N 86  
ASP   C   O    doub N N 87  
ASP   C   OXT  sing N N 88  
ASP   CB  CG   sing N N 89  
ASP   CB  HB2  sing N N 90  
ASP   CB  HB3  sing N N 91  
ASP   CG  OD1  doub N N 92  
ASP   CG  OD2  sing N N 93  
ASP   OD2 HD2  sing N N 94  
ASP   OXT HXT  sing N N 95  
CYS   N   CA   sing N N 96  
CYS   N   H    sing N N 97  
CYS   N   H2   sing N N 98  
CYS   CA  C    sing N N 99  
CYS   CA  CB   sing N N 100 
CYS   CA  HA   sing N N 101 
CYS   C   O    doub N N 102 
CYS   C   OXT  sing N N 103 
CYS   CB  SG   sing N N 104 
CYS   CB  HB2  sing N N 105 
CYS   CB  HB3  sing N N 106 
CYS   SG  HG   sing N N 107 
CYS   OXT HXT  sing N N 108 
GLN   N   CA   sing N N 109 
GLN   N   H    sing N N 110 
GLN   N   H2   sing N N 111 
GLN   CA  C    sing N N 112 
GLN   CA  CB   sing N N 113 
GLN   CA  HA   sing N N 114 
GLN   C   O    doub N N 115 
GLN   C   OXT  sing N N 116 
GLN   CB  CG   sing N N 117 
GLN   CB  HB2  sing N N 118 
GLN   CB  HB3  sing N N 119 
GLN   CG  CD   sing N N 120 
GLN   CG  HG2  sing N N 121 
GLN   CG  HG3  sing N N 122 
GLN   CD  OE1  doub N N 123 
GLN   CD  NE2  sing N N 124 
GLN   NE2 HE21 sing N N 125 
GLN   NE2 HE22 sing N N 126 
GLN   OXT HXT  sing N N 127 
GLU   N   CA   sing N N 128 
GLU   N   H    sing N N 129 
GLU   N   H2   sing N N 130 
GLU   CA  C    sing N N 131 
GLU   CA  CB   sing N N 132 
GLU   CA  HA   sing N N 133 
GLU   C   O    doub N N 134 
GLU   C   OXT  sing N N 135 
GLU   CB  CG   sing N N 136 
GLU   CB  HB2  sing N N 137 
GLU   CB  HB3  sing N N 138 
GLU   CG  CD   sing N N 139 
GLU   CG  HG2  sing N N 140 
GLU   CG  HG3  sing N N 141 
GLU   CD  OE1  doub N N 142 
GLU   CD  OE2  sing N N 143 
GLU   OE2 HE2  sing N N 144 
GLU   OXT HXT  sing N N 145 
GLY   N   CA   sing N N 146 
GLY   N   H    sing N N 147 
GLY   N   H2   sing N N 148 
GLY   CA  C    sing N N 149 
GLY   CA  HA2  sing N N 150 
GLY   CA  HA3  sing N N 151 
GLY   C   O    doub N N 152 
GLY   C   OXT  sing N N 153 
GLY   OXT HXT  sing N N 154 
HIS   N   CA   sing N N 155 
HIS   N   H    sing N N 156 
HIS   N   H2   sing N N 157 
HIS   CA  C    sing N N 158 
HIS   CA  CB   sing N N 159 
HIS   CA  HA   sing N N 160 
HIS   C   O    doub N N 161 
HIS   C   OXT  sing N N 162 
HIS   CB  CG   sing N N 163 
HIS   CB  HB2  sing N N 164 
HIS   CB  HB3  sing N N 165 
HIS   CG  ND1  sing Y N 166 
HIS   CG  CD2  doub Y N 167 
HIS   ND1 CE1  doub Y N 168 
HIS   ND1 HD1  sing N N 169 
HIS   CD2 NE2  sing Y N 170 
HIS   CD2 HD2  sing N N 171 
HIS   CE1 NE2  sing Y N 172 
HIS   CE1 HE1  sing N N 173 
HIS   NE2 HE2  sing N N 174 
HIS   OXT HXT  sing N N 175 
HOH   O   H1   sing N N 176 
HOH   O   H2   sing N N 177 
ILE   N   CA   sing N N 178 
ILE   N   H    sing N N 179 
ILE   N   H2   sing N N 180 
ILE   CA  C    sing N N 181 
ILE   CA  CB   sing N N 182 
ILE   CA  HA   sing N N 183 
ILE   C   O    doub N N 184 
ILE   C   OXT  sing N N 185 
ILE   CB  CG1  sing N N 186 
ILE   CB  CG2  sing N N 187 
ILE   CB  HB   sing N N 188 
ILE   CG1 CD1  sing N N 189 
ILE   CG1 HG12 sing N N 190 
ILE   CG1 HG13 sing N N 191 
ILE   CG2 HG21 sing N N 192 
ILE   CG2 HG22 sing N N 193 
ILE   CG2 HG23 sing N N 194 
ILE   CD1 HD11 sing N N 195 
ILE   CD1 HD12 sing N N 196 
ILE   CD1 HD13 sing N N 197 
ILE   OXT HXT  sing N N 198 
LEU   N   CA   sing N N 199 
LEU   N   H    sing N N 200 
LEU   N   H2   sing N N 201 
LEU   CA  C    sing N N 202 
LEU   CA  CB   sing N N 203 
LEU   CA  HA   sing N N 204 
LEU   C   O    doub N N 205 
LEU   C   OXT  sing N N 206 
LEU   CB  CG   sing N N 207 
LEU   CB  HB2  sing N N 208 
LEU   CB  HB3  sing N N 209 
LEU   CG  CD1  sing N N 210 
LEU   CG  CD2  sing N N 211 
LEU   CG  HG   sing N N 212 
LEU   CD1 HD11 sing N N 213 
LEU   CD1 HD12 sing N N 214 
LEU   CD1 HD13 sing N N 215 
LEU   CD2 HD21 sing N N 216 
LEU   CD2 HD22 sing N N 217 
LEU   CD2 HD23 sing N N 218 
LEU   OXT HXT  sing N N 219 
LYS   N   CA   sing N N 220 
LYS   N   H    sing N N 221 
LYS   N   H2   sing N N 222 
LYS   CA  C    sing N N 223 
LYS   CA  CB   sing N N 224 
LYS   CA  HA   sing N N 225 
LYS   C   O    doub N N 226 
LYS   C   OXT  sing N N 227 
LYS   CB  CG   sing N N 228 
LYS   CB  HB2  sing N N 229 
LYS   CB  HB3  sing N N 230 
LYS   CG  CD   sing N N 231 
LYS   CG  HG2  sing N N 232 
LYS   CG  HG3  sing N N 233 
LYS   CD  CE   sing N N 234 
LYS   CD  HD2  sing N N 235 
LYS   CD  HD3  sing N N 236 
LYS   CE  NZ   sing N N 237 
LYS   CE  HE2  sing N N 238 
LYS   CE  HE3  sing N N 239 
LYS   NZ  HZ1  sing N N 240 
LYS   NZ  HZ2  sing N N 241 
LYS   NZ  HZ3  sing N N 242 
LYS   OXT HXT  sing N N 243 
MET   N   CA   sing N N 244 
MET   N   H    sing N N 245 
MET   N   H2   sing N N 246 
MET   CA  C    sing N N 247 
MET   CA  CB   sing N N 248 
MET   CA  HA   sing N N 249 
MET   C   O    doub N N 250 
MET   C   OXT  sing N N 251 
MET   CB  CG   sing N N 252 
MET   CB  HB2  sing N N 253 
MET   CB  HB3  sing N N 254 
MET   CG  SD   sing N N 255 
MET   CG  HG2  sing N N 256 
MET   CG  HG3  sing N N 257 
MET   SD  CE   sing N N 258 
MET   CE  HE1  sing N N 259 
MET   CE  HE2  sing N N 260 
MET   CE  HE3  sing N N 261 
MET   OXT HXT  sing N N 262 
PHE   N   CA   sing N N 263 
PHE   N   H    sing N N 264 
PHE   N   H2   sing N N 265 
PHE   CA  C    sing N N 266 
PHE   CA  CB   sing N N 267 
PHE   CA  HA   sing N N 268 
PHE   C   O    doub N N 269 
PHE   C   OXT  sing N N 270 
PHE   CB  CG   sing N N 271 
PHE   CB  HB2  sing N N 272 
PHE   CB  HB3  sing N N 273 
PHE   CG  CD1  doub Y N 274 
PHE   CG  CD2  sing Y N 275 
PHE   CD1 CE1  sing Y N 276 
PHE   CD1 HD1  sing N N 277 
PHE   CD2 CE2  doub Y N 278 
PHE   CD2 HD2  sing N N 279 
PHE   CE1 CZ   doub Y N 280 
PHE   CE1 HE1  sing N N 281 
PHE   CE2 CZ   sing Y N 282 
PHE   CE2 HE2  sing N N 283 
PHE   CZ  HZ   sing N N 284 
PHE   OXT HXT  sing N N 285 
PRO   N   CA   sing N N 286 
PRO   N   CD   sing N N 287 
PRO   N   H    sing N N 288 
PRO   CA  C    sing N N 289 
PRO   CA  CB   sing N N 290 
PRO   CA  HA   sing N N 291 
PRO   C   O    doub N N 292 
PRO   C   OXT  sing N N 293 
PRO   CB  CG   sing N N 294 
PRO   CB  HB2  sing N N 295 
PRO   CB  HB3  sing N N 296 
PRO   CG  CD   sing N N 297 
PRO   CG  HG2  sing N N 298 
PRO   CG  HG3  sing N N 299 
PRO   CD  HD2  sing N N 300 
PRO   CD  HD3  sing N N 301 
PRO   OXT HXT  sing N N 302 
SER   N   CA   sing N N 303 
SER   N   H    sing N N 304 
SER   N   H2   sing N N 305 
SER   CA  C    sing N N 306 
SER   CA  CB   sing N N 307 
SER   CA  HA   sing N N 308 
SER   C   O    doub N N 309 
SER   C   OXT  sing N N 310 
SER   CB  OG   sing N N 311 
SER   CB  HB2  sing N N 312 
SER   CB  HB3  sing N N 313 
SER   OG  HG   sing N N 314 
SER   OXT HXT  sing N N 315 
SO4   S   O1   doub N N 316 
SO4   S   O2   doub N N 317 
SO4   S   O3   sing N N 318 
SO4   S   O4   sing N N 319 
THR   N   CA   sing N N 320 
THR   N   H    sing N N 321 
THR   N   H2   sing N N 322 
THR   CA  C    sing N N 323 
THR   CA  CB   sing N N 324 
THR   CA  HA   sing N N 325 
THR   C   O    doub N N 326 
THR   C   OXT  sing N N 327 
THR   CB  OG1  sing N N 328 
THR   CB  CG2  sing N N 329 
THR   CB  HB   sing N N 330 
THR   OG1 HG1  sing N N 331 
THR   CG2 HG21 sing N N 332 
THR   CG2 HG22 sing N N 333 
THR   CG2 HG23 sing N N 334 
THR   OXT HXT  sing N N 335 
TRP   N   CA   sing N N 336 
TRP   N   H    sing N N 337 
TRP   N   H2   sing N N 338 
TRP   CA  C    sing N N 339 
TRP   CA  CB   sing N N 340 
TRP   CA  HA   sing N N 341 
TRP   C   O    doub N N 342 
TRP   C   OXT  sing N N 343 
TRP   CB  CG   sing N N 344 
TRP   CB  HB2  sing N N 345 
TRP   CB  HB3  sing N N 346 
TRP   CG  CD1  doub Y N 347 
TRP   CG  CD2  sing Y N 348 
TRP   CD1 NE1  sing Y N 349 
TRP   CD1 HD1  sing N N 350 
TRP   CD2 CE2  doub Y N 351 
TRP   CD2 CE3  sing Y N 352 
TRP   NE1 CE2  sing Y N 353 
TRP   NE1 HE1  sing N N 354 
TRP   CE2 CZ2  sing Y N 355 
TRP   CE3 CZ3  doub Y N 356 
TRP   CE3 HE3  sing N N 357 
TRP   CZ2 CH2  doub Y N 358 
TRP   CZ2 HZ2  sing N N 359 
TRP   CZ3 CH2  sing Y N 360 
TRP   CZ3 HZ3  sing N N 361 
TRP   CH2 HH2  sing N N 362 
TRP   OXT HXT  sing N N 363 
TYR   N   CA   sing N N 364 
TYR   N   H    sing N N 365 
TYR   N   H2   sing N N 366 
TYR   CA  C    sing N N 367 
TYR   CA  CB   sing N N 368 
TYR   CA  HA   sing N N 369 
TYR   C   O    doub N N 370 
TYR   C   OXT  sing N N 371 
TYR   CB  CG   sing N N 372 
TYR   CB  HB2  sing N N 373 
TYR   CB  HB3  sing N N 374 
TYR   CG  CD1  doub Y N 375 
TYR   CG  CD2  sing Y N 376 
TYR   CD1 CE1  sing Y N 377 
TYR   CD1 HD1  sing N N 378 
TYR   CD2 CE2  doub Y N 379 
TYR   CD2 HD2  sing N N 380 
TYR   CE1 CZ   doub Y N 381 
TYR   CE1 HE1  sing N N 382 
TYR   CE2 CZ   sing Y N 383 
TYR   CE2 HE2  sing N N 384 
TYR   CZ  OH   sing N N 385 
TYR   OH  HH   sing N N 386 
TYR   OXT HXT  sing N N 387 
VAL   N   CA   sing N N 388 
VAL   N   H    sing N N 389 
VAL   N   H2   sing N N 390 
VAL   CA  C    sing N N 391 
VAL   CA  CB   sing N N 392 
VAL   CA  HA   sing N N 393 
VAL   C   O    doub N N 394 
VAL   C   OXT  sing N N 395 
VAL   CB  CG1  sing N N 396 
VAL   CB  CG2  sing N N 397 
VAL   CB  HB   sing N N 398 
VAL   CG1 HG11 sing N N 399 
VAL   CG1 HG12 sing N N 400 
VAL   CG1 HG13 sing N N 401 
VAL   CG2 HG21 sing N N 402 
VAL   CG2 HG22 sing N N 403 
VAL   CG2 HG23 sing N N 404 
VAL   OXT HXT  sing N N 405 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   1PB9 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9GIF 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.023895 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.013980 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.010384 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . ARG   A 1 4   ? 28.445 54.626 18.608 1   30.328 ? 397  ARG   A N    1 
ATOM   2    C CA   . ARG   A 1 4   ? 27.183 54.239 19.296 1   30.368 ? 397  ARG   A CA   1 
ATOM   3    C C    . ARG   A 1 4   ? 27.464 53.033 20.188 1   25.709 ? 397  ARG   A C    1 
ATOM   4    O O    . ARG   A 1 4   ? 27.852 51.989 19.693 1   26.539 ? 397  ARG   A O    1 
ATOM   5    C CB   . ARG   A 1 4   ? 26.107 53.9   18.266 1   35.138 ? 397  ARG   A CB   1 
ATOM   6    C CG   . ARG   A 1 4   ? 24.719 53.725 18.857 1   38.131 ? 397  ARG   A CG   1 
ATOM   7    C CD   . ARG   A 1 4   ? 23.694 53.328 17.815 1   42.002 ? 397  ARG   A CD   1 
ATOM   8    N NE   . ARG   A 1 4   ? 23.47  54.408 16.854 1   43.164 ? 397  ARG   A NE   1 
ATOM   9    C CZ   . ARG   A 1 4   ? 22.715 55.495 17.019 1   51.654 ? 397  ARG   A CZ   1 
ATOM   10   N NH1  . ARG   A 1 4   ? 22.028 55.69  18.133 1   53.353 ? 397  ARG   A NH1  1 
ATOM   11   N NH2  . ARG   A 1 4   ? 22.63  56.391 16.043 1   56.066 ? 397  ARG   A NH2  1 
ATOM   12   H H    . ARG   A 1 4   ? 28.3   55.346 18.083 1   30.354 ? 397  ARG   A H    1 
ATOM   13   H HA   . ARG   A 1 4   ? 26.883 54.997 19.856 1   30.024 ? 397  ARG   A HA   1 
ATOM   14   H HB2  . ARG   A 1 4   ? 26.076 54.617 17.597 1   34.621 ? 397  ARG   A HB2  1 
ATOM   15   H HB3  . ARG   A 1 4   ? 26.36  53.073 17.804 1   34.531 ? 397  ARG   A HB3  1 
ATOM   16   H HG2  . ARG   A 1 4   ? 24.747 53.034 19.554 1   38.21  ? 397  ARG   A HG2  1 
ATOM   17   H HG3  . ARG   A 1 4   ? 24.439 54.566 19.278 1   38.337 ? 397  ARG   A HG3  1 
ATOM   18   H HD2  . ARG   A 1 4   ? 24.006 52.532 17.338 1   41.371 ? 397  ARG   A HD2  1 
ATOM   19   H HD3  . ARG   A 1 4   ? 22.849 53.106 18.256 1   41.414 ? 397  ARG   A HD3  1 
ATOM   20   H HE   . ARG   A 1 4   ? 23.875 54.335 16.086 1   44.898 ? 397  ARG   A HE   1 
ATOM   21   H HH11 . ARG   A 1 4   ? 22.389 55.505 18.917 1   52.188 ? 397  ARG   A HH11 1 
ATOM   22   H HH12 . ARG   A 1 4   ? 21.205 56.009 18.087 1   52.674 ? 397  ARG   A HH12 1 
ATOM   23   H HH21 . ARG   A 1 4   ? 22.929 56.196 15.234 1   54.475 ? 397  ARG   A HH21 1 
ATOM   24   H HH22 . ARG   A 1 4   ? 22.272 57.183 16.207 1   54.614 ? 397  ARG   A HH22 1 
ATOM   25   N N    . LEU   A 1 5   ? 27.297 53.196 21.499 1   22.866 ? 398  LEU   A N    1 
ATOM   26   C CA   . LEU   A 1 5   ? 27.502 52.104 22.442 1   22.03  ? 398  LEU   A CA   1 
ATOM   27   C C    . LEU   A 1 5   ? 26.42  51.034 22.299 1   17.99  ? 398  LEU   A C    1 
ATOM   28   O O    . LEU   A 1 5   ? 25.25  51.349 22.154 1   17.993 ? 398  LEU   A O    1 
ATOM   29   C CB   . LEU   A 1 5   ? 27.502 52.634 23.873 1   22.12  ? 398  LEU   A CB   1 
ATOM   30   C CG   . LEU   A 1 5   ? 28.85  53.063 24.44  1   25.131 ? 398  LEU   A CG   1 
ATOM   31   C CD1  . LEU   A 1 5   ? 29.558 53.988 23.466 1   30.537 ? 398  LEU   A CD1  1 
ATOM   32   C CD2  . LEU   A 1 5   ? 28.605 53.717 25.79  1   25.466 ? 398  LEU   A CD2  1 
ATOM   33   H H    . LEU   A 1 5   ? 27.046 54.014 21.82  1   23.436 ? 398  LEU   A H    1 
ATOM   34   H HA   . LEU   A 1 5   ? 28.383 51.692 22.251 1   21.416 ? 398  LEU   A HA   1 
ATOM   35   H HB2  . LEU   A 1 5   ? 26.888 53.403 23.917 1   22.782 ? 398  LEU   A HB2  1 
ATOM   36   H HB3  . LEU   A 1 5   ? 27.131 51.934 24.459 1   22.728 ? 398  LEU   A HB3  1 
ATOM   37   H HG   . LEU   A 1 5   ? 29.409 52.255 24.575 1   25.514 ? 398  LEU   A HG   1 
ATOM   38   H HD11 . LEU   A 1 5   ? 29.93  53.468 22.734 1   28.823 ? 398  LEU   A HD11 1 
ATOM   39   H HD12 . LEU   A 1 5   ? 30.272 54.454 23.925 1   29.064 ? 398  LEU   A HD12 1 
ATOM   40   H HD13 . LEU   A 1 5   ? 28.925 54.636 23.114 1   28.761 ? 398  LEU   A HD13 1 
ATOM   41   H HD21 . LEU   A 1 5   ? 28.128 53.098 26.369 1   25.362 ? 398  LEU   A HD21 1 
ATOM   42   H HD22 . LEU   A 1 5   ? 28.073 54.521 25.67  1   25.345 ? 398  LEU   A HD22 1 
ATOM   43   H HD23 . LEU   A 1 5   ? 29.455 53.95  26.198 1   25.362 ? 398  LEU   A HD23 1 
ATOM   44   N N    . LYS   A 1 6   ? 26.827 49.774 22.436 1   17.054 ? 399  LYS   A N    1 
ATOM   45   C CA   . LYS   A 1 6   ? 25.91  48.657 22.519 1   17.814 ? 399  LYS   A CA   1 
ATOM   46   C C    . LYS   A 1 6   ? 25.589 48.365 23.985 1   14.852 ? 399  LYS   A C    1 
ATOM   47   O O    . LYS   A 1 6   ? 26.414 47.83  24.727 1   15.338 ? 399  LYS   A O    1 
ATOM   48   C CB   . LYS   A 1 6   ? 26.515 47.449 21.794 1   19.362 ? 399  LYS   A CB   1 
ATOM   49   C CG   . LYS   A 1 6   ? 26.708 47.708 20.29  1   21.508 ? 399  LYS   A CG   1 
ATOM   50   C CD   . LYS   A 1 6   ? 27.248 46.522 19.513 1   26.667 ? 399  LYS   A CD   1 
ATOM   51   C CE   . LYS   A 1 6   ? 28.593 46.124 20.038 1   32.486 ? 399  LYS   A CE   1 
ATOM   52   N NZ   . LYS   A 1 6   ? 29.212 45.164 19.11  1   39.764 ? 399  LYS   A NZ   1 
ATOM   53   H H    . LYS   A 1 6   ? 27.724 49.603 22.48  1   17.512 ? 399  LYS   A H    1 
ATOM   54   H HA   . LYS   A 1 6   ? 25.071 48.905 22.053 1   17.297 ? 399  LYS   A HA   1 
ATOM   55   H HB2  . LYS   A 1 6   ? 27.384 47.237 22.196 1   19.582 ? 399  LYS   A HB2  1 
ATOM   56   H HB3  . LYS   A 1 6   ? 25.927 46.673 21.91  1   19.482 ? 399  LYS   A HB3  1 
ATOM   57   H HG2  . LYS   A 1 6   ? 25.843 47.971 19.907 1   22.061 ? 399  LYS   A HG2  1 
ATOM   58   H HG3  . LYS   A 1 6   ? 27.324 48.465 20.181 1   22.038 ? 399  LYS   A HG3  1 
ATOM   59   H HD2  . LYS   A 1 6   ? 26.629 45.764 19.598 1   26.595 ? 399  LYS   A HD2  1 
ATOM   60   H HD3  . LYS   A 1 6   ? 27.326 46.76  18.564 1   26.643 ? 399  LYS   A HD3  1 
ATOM   61   H HE2  . LYS   A 1 6   ? 29.164 46.908 20.122 1   32.456 ? 399  LYS   A HE2  1 
ATOM   62   H HE3  . LYS   A 1 6   ? 28.503 45.707 20.914 1   32.362 ? 399  LYS   A HE3  1 
ATOM   63   H HZ1  . LYS   A 1 6   ? 29.347 45.558 18.305 1   37.257 ? 399  LYS   A HZ1  1 
ATOM   64   H HZ2  . LYS   A 1 6   ? 28.671 44.446 19.004 1   37.268 ? 399  LYS   A HZ2  1 
ATOM   65   H HZ3  . LYS   A 1 6   ? 30.009 44.889 19.443 1   37.324 ? 399  LYS   A HZ3  1 
ATOM   66   N N    . ILE   A 1 7   ? 24.36  48.684 24.38  1   13.452 ? 400  ILE   A N    1 
ATOM   67   C CA   . ILE   A 1 7   ? 23.893 48.427 25.732 1   12.049 ? 400  ILE   A CA   1 
ATOM   68   C C    . ILE   A 1 7   ? 23.212 47.074 25.767 1   12.108 ? 400  ILE   A C    1 
ATOM   69   O O    . ILE   A 1 7   ? 22.294 46.816 24.985 1   13.286 ? 400  ILE   A O    1 
ATOM   70   C CB   . ILE   A 1 7   ? 22.903 49.501 26.199 1   11.563 ? 400  ILE   A CB   1 
ATOM   71   C CG1  . ILE   A 1 7   ? 23.434 50.923 25.967 1   12.249 ? 400  ILE   A CG1  1 
ATOM   72   C CG2  . ILE   A 1 7   ? 22.509 49.231 27.656 1   10.786 ? 400  ILE   A CG2  1 
ATOM   73   C CD1  . ILE   A 1 7   ? 24.76  51.231 26.632 1   13.13  ? 400  ILE   A CD1  1 
ATOM   74   H H    . ILE   A 1 7   ? 23.786 49.075 23.786 1   13.476 ? 400  ILE   A H    1 
ATOM   75   H HA   . ILE   A 1 7   ? 24.658 48.42  26.337 1   12.246 ? 400  ILE   A HA   1 
ATOM   76   H HB   . ILE   A 1 7   ? 22.095 49.404 25.656 1   11.654 ? 400  ILE   A HB   1 
ATOM   77   H HG12 . ILE   A 1 7   ? 23.531 51.064 25.004 1   12.331 ? 400  ILE   A HG12 1 
ATOM   78   H HG13 . ILE   A 1 7   ? 22.767 51.56  26.293 1   12.294 ? 400  ILE   A HG13 1 
ATOM   79   H HG21 . ILE   A 1 7   ? 22.169 50.048 28.057 1   11.019 ? 400  ILE   A HG21 1 
ATOM   80   H HG22 . ILE   A 1 7   ? 23.287 48.928 28.154 1   11.025 ? 400  ILE   A HG22 1 
ATOM   81   H HG23 . ILE   A 1 7   ? 21.819 48.547 27.687 1   11.018 ? 400  ILE   A HG23 1 
ATOM   82   H HD11 . ILE   A 1 7   ? 24.714 51.001 27.579 1   12.852 ? 400  ILE   A HD11 1 
ATOM   83   H HD12 . ILE   A 1 7   ? 24.955 52.183 26.54  1   12.86  ? 400  ILE   A HD12 1 
ATOM   84   H HD13 . ILE   A 1 7   ? 25.47  50.714 26.207 1   12.857 ? 400  ILE   A HD13 1 
ATOM   85   N N    . VAL   A 1 8   ? 23.586 46.262 26.739 1   11.6   ? 401  VAL   A N    1 
ATOM   86   C CA   . VAL   A 1 8   ? 22.847 45.039 26.996 1   11.099 ? 401  VAL   A CA   1 
ATOM   87   C C    . VAL   A 1 8   ? 22.081 45.188 28.308 1   10.89  ? 401  VAL   A C    1 
ATOM   88   O O    . VAL   A 1 8   ? 22.589 45.752 29.283 1   11.3   ? 401  VAL   A O    1 
ATOM   89   C CB   . VAL   A 1 8   ? 23.714 43.772 26.99  1   10.974 ? 401  VAL   A CB   1 
ATOM   90   C CG1  . VAL   A 1 8   ? 24.704 43.699 28.162 1   11.589 ? 401  VAL   A CG1  1 
ATOM   91   C CG2  . VAL   A 1 8   ? 22.846 42.525 26.952 1   11.073 ? 401  VAL   A CG2  1 
ATOM   92   H H    . VAL   A 1 8   ? 24.312 46.464 27.257 1   11.61  ? 401  VAL   A H    1 
ATOM   93   H HA   . VAL   A 1 8   ? 22.19  44.941 26.283 1   11.143 ? 401  VAL   A HA   1 
ATOM   94   H HB   . VAL   A 1 8   ? 24.241 43.79  26.158 1   11.15  ? 401  VAL   A HB   1 
ATOM   95   H HG11 . VAL   A 1 8   ? 24.228 43.459 28.976 1   11.403 ? 401  VAL   A HG11 1 
ATOM   96   H HG12 . VAL   A 1 8   ? 25.133 44.562 28.282 1   11.406 ? 401  VAL   A HG12 1 
ATOM   97   H HG13 . VAL   A 1 8   ? 25.38  43.026 27.974 1   11.405 ? 401  VAL   A HG13 1 
ATOM   98   H HG21 . VAL   A 1 8   ? 23.403 41.748 26.776 1   11.043 ? 401  VAL   A HG21 1 
ATOM   99   H HG22 . VAL   A 1 8   ? 22.183 42.612 26.247 1   11.044 ? 401  VAL   A HG22 1 
ATOM   100  H HG23 . VAL   A 1 8   ? 22.397 42.414 27.806 1   11.043 ? 401  VAL   A HG23 1 
ATOM   101  N N    . THR   A 1 9   ? 20.849 44.688 28.306 1   10.226 ? 402  THR   A N    1 
ATOM   102  C CA   . THR   A 1 9   ? 20.046 44.648 29.514 1   10.234 ? 402  THR   A CA   1 
ATOM   103  C C    . THR   A 1 9   ? 19.249 43.344 29.538 1   11.464 ? 402  THR   A C    1 
ATOM   104  O O    . THR   A 1 9   ? 19.403 42.467 28.677 1   10.599 ? 402  THR   A O    1 
ATOM   105  C CB   . THR   A 1 9   ? 19.17  45.91  29.578 1   10.18  ? 402  THR   A CB   1 
ATOM   106  O OG1  . THR   A 1 9   ? 18.659 46.062 30.903 1   8.959  ? 402  THR   A OG1  1 
ATOM   107  C CG2  . THR   A 1 9   ? 18     45.919 28.596 1   10.251 ? 402  THR   A CG2  1 
ATOM   108  H H    . THR   A 1 9   ? 20.494 44.362 27.53  1   10.4   ? 402  THR   A H    1 
ATOM   109  H HA   . THR   A 1 9   ? 20.651 44.654 30.288 1   10.446 ? 402  THR   A HA   1 
ATOM   110  H HB   . THR   A 1 9   ? 19.738 46.69  29.37  1   9.951  ? 402  THR   A HB   1 
ATOM   111  H HG1  . THR   A 1 9   ? 18.188 45.381 31.111 0   30     ? 402  THR   A HG1  1 
ATOM   112  H HG21 . THR   A 1 9   ? 17.678 46.829 28.482 1   10.231 ? 402  THR   A HG21 1 
ATOM   113  H HG22 . THR   A 1 9   ? 17.281 45.363 28.941 1   10.235 ? 402  THR   A HG22 1 
ATOM   114  H HG23 . THR   A 1 9   ? 18.294 45.571 27.737 1   10.231 ? 402  THR   A HG23 1 
ATOM   115  N N    . ILE   A 1 10  ? 18.349 43.253 30.522 1   10.977 ? 403  ILE   A N    1 
ATOM   116  C CA   . ILE   A 1 10  ? 17.579 42.053 30.743 1   11.08  ? 403  ILE   A CA   1 
ATOM   117  C C    . ILE   A 1 10  ? 16.198 42.47  31.246 1   10.839 ? 403  ILE   A C    1 
ATOM   118  O O    . ILE   A 1 10  ? 16.078 43.466 31.965 1   10.171 ? 403  ILE   A O    1 
ATOM   119  C CB   . ILE   A 1 10  ? 18.325 41.167 31.759 1   11.548 ? 403  ILE   A CB   1 
ATOM   120  C CG1  . ILE   A 1 10  ? 17.704 39.792 31.845 1   11.914 ? 403  ILE   A CG1  1 
ATOM   121  C CG2  . ILE   A 1 10  ? 18.389 41.844 33.139 1   11.151 ? 403  ILE   A CG2  1 
ATOM   122  C CD1  . ILE   A 1 10  ? 18.472 38.813 32.694 1   12.264 ? 403  ILE   A CD1  1 
ATOM   123  H H    . ILE   A 1 10  ? 18.216 43.968 31.076 1   11.101 ? 403  ILE   A H    1 
ATOM   124  H HA   . ILE   A 1 10  ? 17.484 41.568 29.9   1   11.098 ? 403  ILE   A HA   1 
ATOM   125  H HB   . ILE   A 1 10  ? 19.242 41.058 31.438 1   11.453 ? 403  ILE   A HB   1 
ATOM   126  H HG12 . ILE   A 1 10  ? 16.8   39.878 32.209 1   11.902 ? 403  ILE   A HG12 1 
ATOM   127  H HG13 . ILE   A 1 10  ? 17.627 39.427 30.939 1   11.902 ? 403  ILE   A HG13 1 
ATOM   128  H HG21 . ILE   A 1 10  ? 19.151 41.499 33.634 1   11.269 ? 403  ILE   A HG21 1 
ATOM   129  H HG22 . ILE   A 1 10  ? 17.573 41.655 33.632 1   11.265 ? 403  ILE   A HG22 1 
ATOM   130  H HG23 . ILE   A 1 10  ? 18.486 42.804 33.031 1   11.255 ? 403  ILE   A HG23 1 
ATOM   131  H HD11 . ILE   A 1 10  ? 19.313 38.587 32.253 1   12.157 ? 403  ILE   A HD11 1 
ATOM   132  H HD12 . ILE   A 1 10  ? 17.941 38.003 32.812 1   12.159 ? 403  ILE   A HD12 1 
ATOM   133  H HD13 . ILE   A 1 10  ? 18.66  39.203 33.568 1   12.147 ? 403  ILE   A HD13 1 
ATOM   134  N N    . HIS   A 1 11  ? 15.171 41.686 30.912 1   10.078 ? 404  HIS   A N    1 
ATOM   135  C CA   . HIS   A 1 11  ? 13.854 41.875 31.496 1   11.123 ? 404  HIS   A CA   1 
ATOM   136  C C    . HIS   A 1 11  ? 13.93  41.719 33.014 1   9.627  ? 404  HIS   A C    1 
ATOM   137  O O    . HIS   A 1 11  ? 14.363 40.666 33.492 1   9.349  ? 404  HIS   A O    1 
ATOM   138  C CB   . HIS   A 1 11  ? 12.889 40.853 30.865 1   12.755 ? 404  HIS   A CB   1 
ATOM   139  C CG   . HIS   A 1 11  ? 11.488 40.929 31.363 1   15.649 ? 404  HIS   A CG   1 
ATOM   140  N ND1  . HIS   A 1 11  ? 10.832 42.113 31.621 1   17.488 ? 404  HIS   A ND1  1 
ATOM   141  C CD2  . HIS   A 1 11  ? 10.581 39.935 31.618 1   17.056 ? 404  HIS   A CD2  1 
ATOM   142  C CE1  . HIS   A 1 11  ? 9.59   41.856 32.029 1   17.205 ? 404  HIS   A CE1  1 
ATOM   143  N NE2  . HIS   A 1 11  ? 9.419  40.544 32.045 1   21.017 ? 404  HIS   A NE2  1 
ATOM   144  H H    . HIS   A 1 11  ? 15.294 41.014 30.304 1   10.508 ? 404  HIS   A H    1 
ATOM   145  H HA   . HIS   A 1 11  ? 13.546 42.791 31.286 1   10.862 ? 404  HIS   A HA   1 
ATOM   146  H HB2  . HIS   A 1 11  ? 12.886 40.986 29.892 1   12.977 ? 404  HIS   A HB2  1 
ATOM   147  H HB3  . HIS   A 1 11  ? 13.236 39.951 31.035 1   12.977 ? 404  HIS   A HB3  1 
ATOM   148  H HD1  . HIS   A 1 11  ? 11.195 42.928 31.545 0   30     ? 404  HIS   A HD1  1 
ATOM   149  H HD2  . HIS   A 1 11  ? 10.715 39.012 31.542 1   17.624 ? 404  HIS   A HD2  1 
ATOM   150  H HE1  . HIS   A 1 11  ? 8.955  42.496 32.281 1   18.074 ? 404  HIS   A HE1  1 
ATOM   151  H HE2  . HIS   A 1 11  ? 8.682  40.145 32.275 0   30     ? 404  HIS   A HE2  1 
ATOM   152  N N    . GLN   A 1 12  ? 13.472 42.725 33.784 1   9.03   ? 405  GLN   A N    1 
ATOM   153  C CA   . GLN   A 1 12  ? 13.451 42.604 35.232 1   8.878  ? 405  GLN   A CA   1 
ATOM   154  C C    . GLN   A 1 12  ? 12.709 43.796 35.854 1   9.657  ? 405  GLN   A C    1 
ATOM   155  O O    . GLN   A 1 12  ? 13.305 44.842 36.124 1   8.801  ? 405  GLN   A O    1 
ATOM   156  C CB   . GLN   A 1 12  ? 14.897 42.58  35.725 1   9.1    ? 405  GLN   A CB   1 
ATOM   157  C CG   . GLN   A 1 12  ? 15.091 42.113 37.158 1   9.858  ? 405  GLN   A CG   1 
ATOM   158  C CD   . GLN   A 1 12  ? 14.986 40.62  37.37  1   10.367 ? 405  GLN   A CD   1 
ATOM   159  O OE1  . GLN   A 1 12  ? 14.851 40.164 38.494 1   11.215 ? 405  GLN   A OE1  1 
ATOM   160  N NE2  . GLN   A 1 12  ? 15.011 39.844 36.301 1   10.366 ? 405  GLN   A NE2  1 
ATOM   161  H H    . GLN   A 1 12  ? 13.17  43.496 33.396 1   9.162  ? 405  GLN   A H    1 
ATOM   162  H HA   . GLN   A 1 12  ? 12.992 41.761 35.479 1   9.104  ? 405  GLN   A HA   1 
ATOM   163  H HB2  . GLN   A 1 12  ? 15.421 42.001 35.136 1   9.232  ? 405  GLN   A HB2  1 
ATOM   164  H HB3  . GLN   A 1 12  ? 15.265 43.484 35.641 1   9.219  ? 405  GLN   A HB3  1 
ATOM   165  H HG2  . GLN   A 1 12  ? 15.974 42.402 37.467 1   9.786  ? 405  GLN   A HG2  1 
ATOM   166  H HG3  . GLN   A 1 12  ? 14.425 42.55  37.729 1   9.792  ? 405  GLN   A HG3  1 
ATOM   167  H HE21 . GLN   A 1 12  ? 14.272 39.432 36.037 1   10.364 ? 405  GLN   A HE21 1 
ATOM   168  H HE22 . GLN   A 1 12  ? 15.767 39.737 35.85  1   10.357 ? 405  GLN   A HE22 1 
ATOM   169  N N    . GLU   A 1 13  ? 11.4   43.64  36.037 1   9.991  ? 406  GLU   A N    1 
ATOM   170  C CA   . GLU   A 1 13  ? 10.581 44.707 36.573 1   10.824 ? 406  GLU   A CA   1 
ATOM   171  C C    . GLU   A 1 13  ? 10.981 44.909 38.024 1   10.193 ? 406  GLU   A C    1 
ATOM   172  O O    . GLU   A 1 13  ? 11.281 43.926 38.692 1   10.287 ? 406  GLU   A O    1 
ATOM   173  C CB   . GLU   A 1 13  ? 9.116  44.334 36.43  1   12.034 ? 406  GLU   A CB   1 
ATOM   174  C CG   . GLU   A 1 13  ? 8.726  44.125 34.979 1   13.975 ? 406  GLU   A CG   1 
ATOM   175  C CD   . GLU   A 1 13  ? 7.293  43.669 34.778 1   16.729 ? 406  GLU   A CD   1 
ATOM   176  O OE1  . GLU   A 1 13  ? 6.522  43.738 35.747 1   16.708 ? 406  GLU   A OE1  1 
ATOM   177  O OE2  . GLU   A 1 13  ? 7.012  43.254 33.638 1   19.16  ? 406  GLU   A OE2  1 
ATOM   178  H H    . GLU   A 1 13  ? 11.01  42.837 35.838 1   10.135 ? 406  GLU   A H    1 
ATOM   179  H HA   . GLU   A 1 13  ? 10.767 45.533 36.059 1   10.71  ? 406  GLU   A HA   1 
ATOM   180  H HB2  . GLU   A 1 13  ? 8.945  43.513 36.937 1   12.177 ? 406  GLU   A HB2  1 
ATOM   181  H HB3  . GLU   A 1 13  ? 8.567  45.047 36.819 1   12.177 ? 406  GLU   A HB3  1 
ATOM   182  H HG2  . GLU   A 1 13  ? 8.856  44.965 34.49  1   14.05  ? 406  GLU   A HG2  1 
ATOM   183  H HG3  . GLU   A 1 13  ? 9.321  43.457 34.578 1   14.013 ? 406  GLU   A HG3  1 
ATOM   184  N N    . PRO   A 1 14  ? 11.014 46.142 38.584 1   9.597  ? 407  PRO   A N    1 
ATOM   185  C CA   . PRO   A 1 14  ? 10.636 47.383 37.909 1   9.314  ? 407  PRO   A CA   1 
ATOM   186  C C    . PRO   A 1 14  ? 11.774 48.142 37.226 1   9.023  ? 407  PRO   A C    1 
ATOM   187  O O    . PRO   A 1 14  ? 11.592 49.295 36.831 1   9.977  ? 407  PRO   A O    1 
ATOM   188  C CB   . PRO   A 1 14  ? 10.047 48.176 39.062 1   9.461  ? 407  PRO   A CB   1 
ATOM   189  C CG   . PRO   A 1 14  ? 11.036 47.839 40.178 1   9.5    ? 407  PRO   A CG   1 
ATOM   190  C CD   . PRO   A 1 14  ? 11.358 46.371 40.002 1   9.708  ? 407  PRO   A CD   1 
ATOM   191  H HA   . PRO   A 1 14  ? 9.931  47.197 37.256 1   9.368  ? 407  PRO   A HA   1 
ATOM   192  H HB2  . PRO   A 1 14  ? 10.037 49.133 38.87  1   9.436  ? 407  PRO   A HB2  1 
ATOM   193  H HB3  . PRO   A 1 14  ? 9.145  47.869 39.281 1   9.436  ? 407  PRO   A HB3  1 
ATOM   194  H HG2  . PRO   A 1 14  ? 11.847 48.38  40.099 1   9.536  ? 407  PRO   A HG2  1 
ATOM   195  H HG3  . PRO   A 1 14  ? 10.636 47.999 41.056 1   9.538  ? 407  PRO   A HG3  1 
ATOM   196  H HD2  . PRO   A 1 14  ? 12.304 46.19  40.165 1   9.634  ? 407  PRO   A HD2  1 
ATOM   197  H HD3  . PRO   A 1 14  ? 10.813 45.811 40.588 1   9.643  ? 407  PRO   A HD3  1 
ATOM   198  N N    . PHE   A 1 15  ? 12.916 47.471 37.042 1   9.008  ? 408  PHE   A N    1 
ATOM   199  C CA   . PHE   A 1 15  ? 14.093 48.1   36.468 1   8.975  ? 408  PHE   A CA   1 
ATOM   200  C C    . PHE   A 1 15  ? 13.992 48.185 34.945 1   8.382  ? 408  PHE   A C    1 
ATOM   201  O O    . PHE   A 1 15  ? 14.403 49.173 34.346 1   7.202  ? 408  PHE   A O    1 
ATOM   202  C CB   . PHE   A 1 15  ? 15.355 47.353 36.932 1   9.122  ? 408  PHE   A CB   1 
ATOM   203  C CG   . PHE   A 1 15  ? 15.534 47.593 38.422 1   8.713  ? 408  PHE   A CG   1 
ATOM   204  C CD1  . PHE   A 1 15  ? 16.113 48.769 38.891 1   8.72   ? 408  PHE   A CD1  1 
ATOM   205  C CD2  . PHE   A 1 15  ? 15.04  46.669 39.345 1   9.037  ? 408  PHE   A CD2  1 
ATOM   206  C CE1  . PHE   A 1 15  ? 16.145 49.025 40.262 1   9.479  ? 408  PHE   A CE1  1 
ATOM   207  C CE2  . PHE   A 1 15  ? 15.118 46.928 40.722 1   9.047  ? 408  PHE   A CE2  1 
ATOM   208  C CZ   . PHE   A 1 15  ? 15.641 48.107 41.161 1   9.065  ? 408  PHE   A CZ   1 
ATOM   209  H H    . PHE   A 1 15  ? 12.963 46.59  37.276 1   9.018  ? 408  PHE   A H    1 
ATOM   210  H HA   . PHE   A 1 15  ? 14.143 49.026 36.819 1   8.896  ? 408  PHE   A HA   1 
ATOM   211  H HB2  . PHE   A 1 15  ? 15.25  46.391 36.76  1   8.995  ? 408  PHE   A HB2  1 
ATOM   212  H HB3  . PHE   A 1 15  ? 16.135 47.694 36.443 1   9.004  ? 408  PHE   A HB3  1 
ATOM   213  H HD1  . PHE   A 1 15  ? 16.408 49.424 38.28  1   8.89   ? 408  PHE   A HD1  1 
ATOM   214  H HD2  . PHE   A 1 15  ? 14.63  45.876 39.039 1   8.967  ? 408  PHE   A HD2  1 
ATOM   215  H HE1  . PHE   A 1 15  ? 16.546 49.819 40.579 1   9.195  ? 408  PHE   A HE1  1 
ATOM   216  H HE2  . PHE   A 1 15  ? 14.783 46.298 41.341 1   9.049  ? 408  PHE   A HE2  1 
ATOM   217  H HZ   . PHE   A 1 15  ? 15.736 48.26  42.086 1   9.154  ? 408  PHE   A HZ   1 
ATOM   218  N N    . VAL   A 1 16  ? 13.542 47.092 34.335 1   8.915  ? 409  VAL   A N    1 
ATOM   219  C CA   . VAL   A 1 16  ? 13.408 47.006 32.891 1   9.317  ? 409  VAL   A CA   1 
ATOM   220  C C    . VAL   A 1 16  ? 12.134 46.231 32.571 1   9.691  ? 409  VAL   A C    1 
ATOM   221  O O    . VAL   A 1 16  ? 12.063 45.022 32.775 1   10.21  ? 409  VAL   A O    1 
ATOM   222  C CB   . VAL   A 1 16  ? 14.606 46.337 32.193 1   9.6    ? 409  VAL   A CB   1 
ATOM   223  C CG1  . VAL   A 1 16  ? 14.441 46.412 30.676 1   10.089 ? 409  VAL   A CG1  1 
ATOM   224  C CG2  . VAL   A 1 16  ? 15.933 46.95  32.595 1   9.47   ? 409  VAL   A CG2  1 
ATOM   225  H H    . VAL   A 1 16  ? 13.316 46.364 34.839 1   8.884  ? 409  VAL   A H    1 
ATOM   226  H HA   . VAL   A 1 16  ? 13.317 47.91  32.537 1   9.34   ? 409  VAL   A HA   1 
ATOM   227  H HB   . VAL   A 1 16  ? 14.61  45.389 32.459 1   9.617  ? 409  VAL   A HB   1 
ATOM   228  H HG11 . VAL   A 1 16  ? 14.15  47.304 30.424 1   9.933  ? 409  VAL   A HG11 1 
ATOM   229  H HG12 . VAL   A 1 16  ? 13.777 45.763 30.388 1   9.938  ? 409  VAL   A HG12 1 
ATOM   230  H HG13 . VAL   A 1 16  ? 15.29  46.215 30.246 1   9.935  ? 409  VAL   A HG13 1 
ATOM   231  H HG21 . VAL   A 1 16  ? 16.645 46.554 32.069 1   9.505  ? 409  VAL   A HG21 1 
ATOM   232  H HG22 . VAL   A 1 16  ? 16.097 46.782 33.538 1   9.499  ? 409  VAL   A HG22 1 
ATOM   233  H HG23 . VAL   A 1 16  ? 15.909 47.909 32.437 1   9.506  ? 409  VAL   A HG23 1 
ATOM   234  N N    . TYR   A 1 17  ? 11.129 46.96  32.091 1   9.987  ? 410  TYR   A N    1 
ATOM   235  C CA   . TYR   A 1 17  ? 9.949  46.387 31.47  1   9.744  ? 410  TYR   A CA   1 
ATOM   236  C C    . TYR   A 1 17  ? 10.266 46.108 30.003 1   9.368  ? 410  TYR   A C    1 
ATOM   237  O O    . TYR   A 1 17  ? 10.996 46.868 29.396 1   8.659  ? 410  TYR   A O    1 
ATOM   238  C CB   . TYR   A 1 17  ? 8.837  47.424 31.61  1   10.012 ? 410  TYR   A CB   1 
ATOM   239  C CG   . TYR   A 1 17  ? 8.331  47.608 33.032 1   10.287 ? 410  TYR   A CG   1 
ATOM   240  C CD1  . TYR   A 1 17  ? 8.977  48.442 33.939 1   10.398 ? 410  TYR   A CD1  1 
ATOM   241  C CD2  . TYR   A 1 17  ? 7.173  46.97  33.454 1   11.166 ? 410  TYR   A CD2  1 
ATOM   242  C CE1  . TYR   A 1 17  ? 8.473  48.637 35.222 1   11.032 ? 410  TYR   A CE1  1 
ATOM   243  C CE2  . TYR   A 1 17  ? 6.674  47.132 34.736 1   12.135 ? 410  TYR   A CE2  1 
ATOM   244  C CZ   . TYR   A 1 17  ? 7.337  47.952 35.634 1   13.148 ? 410  TYR   A CZ   1 
ATOM   245  O OH   . TYR   A 1 17  ? 6.835  48.093 36.904 1   12.574 ? 410  TYR   A OH   1 
ATOM   246  H H    . TYR   A 1 17  ? 11.185 47.87  32.154 1   9.862  ? 410  TYR   A H    1 
ATOM   247  H HA   . TYR   A 1 17  ? 9.693  45.546 31.935 1   9.773  ? 410  TYR   A HA   1 
ATOM   248  H HB2  . TYR   A 1 17  ? 9.168  48.287 31.275 1   10.002 ? 410  TYR   A HB2  1 
ATOM   249  H HB3  . TYR   A 1 17  ? 8.084  47.151 31.039 1   10.019 ? 410  TYR   A HB3  1 
ATOM   250  H HD1  . TYR   A 1 17  ? 9.753  48.907 33.673 1   10.522 ? 410  TYR   A HD1  1 
ATOM   251  H HD2  . TYR   A 1 17  ? 6.719  46.398 32.855 1   11.166 ? 410  TYR   A HD2  1 
ATOM   252  H HE1  . TYR   A 1 17  ? 8.936  49.186 35.832 1   11.333 ? 410  TYR   A HE1  1 
ATOM   253  H HE2  . TYR   A 1 17  ? 5.898  46.67  35.004 1   12.093 ? 410  TYR   A HE2  1 
ATOM   254  H HH   . TYR   A 1 17  ? 7.322  48.631 37.363 0   30     ? 410  TYR   A HH   1 
ATOM   255  N N    . VAL   A 1 18  ? 9.672  45.055 29.451 1   10.092 ? 411  VAL   A N    1 
ATOM   256  C CA   . VAL   A 1 18  ? 9.79   44.696 28.048 1   10.935 ? 411  VAL   A CA   1 
ATOM   257  C C    . VAL   A 1 18  ? 8.388  44.398 27.524 1   12.048 ? 411  VAL   A C    1 
ATOM   258  O O    . VAL   A 1 18  ? 7.685  43.52  28.043 1   11.421 ? 411  VAL   A O    1 
ATOM   259  C CB   . VAL   A 1 18  ? 10.732 43.504 27.8   1   12.092 ? 411  VAL   A CB   1 
ATOM   260  C CG1  . VAL   A 1 18  ? 10.935 43.272 26.308 1   13.118 ? 411  VAL   A CG1  1 
ATOM   261  C CG2  . VAL   A 1 18  ? 12.088 43.698 28.464 1   11.73  ? 411  VAL   A CG2  1 
ATOM   262  H H    . VAL   A 1 18  ? 9.158  44.521 29.986 1   10.104 ? 411  VAL   A H    1 
ATOM   263  H HA   . VAL   A 1 18  ? 10.143 45.466 27.566 1   11.163 ? 411  VAL   A HA   1 
ATOM   264  H HB   . VAL   A 1 18  ? 10.305 42.703 28.186 1   11.982 ? 411  VAL   A HB   1 
ATOM   265  H HG11 . VAL   A 1 18  ? 11.266 44.087 25.895 1   12.816 ? 411  VAL   A HG11 1 
ATOM   266  H HG12 . VAL   A 1 18  ? 10.09  43.023 25.898 1   12.813 ? 411  VAL   A HG12 1 
ATOM   267  H HG13 . VAL   A 1 18  ? 11.579 42.557 26.176 1   12.848 ? 411  VAL   A HG13 1 
ATOM   268  H HG21 . VAL   A 1 18  ? 12.708 43.022 28.144 1   11.856 ? 411  VAL   A HG21 1 
ATOM   269  H HG22 . VAL   A 1 18  ? 11.991 43.617 29.428 1   11.838 ? 411  VAL   A HG22 1 
ATOM   270  H HG23 . VAL   A 1 18  ? 12.431 44.58  28.248 1   11.875 ? 411  VAL   A HG23 1 
ATOM   271  N N    . LYS   A 1 19  ? 7.968  45.182 26.524 1   11.939 ? 412  LYS   A N    1 
ATOM   272  C CA   . LYS   A 1 19  ? 6.666  44.99  25.907 1   14.042 ? 412  LYS   A CA   1 
ATOM   273  C C    . LYS   A 1 19  ? 6.811  44.894 24.379 1   15.189 ? 412  LYS   A C    1 
ATOM   274  O O    . LYS   A 1 19  ? 7.737  45.444 23.784 1   13.373 ? 412  LYS   A O    1 
ATOM   275  C CB   . LYS   A 1 19  ? 5.772  46.176 26.271 1   13.134 ? 412  LYS   A CB   1 
ATOM   276  C CG   . LYS   A 1 19  ? 5.381  46.317 27.741 1   14.879 ? 412  LYS   A CG   1 
ATOM   277  C CD   . LYS   A 1 19  ? 4.691  45.139 28.413 1   15.422 ? 412  LYS   A CD   1 
ATOM   278  C CE   . LYS   A 1 19  ? 4.459  45.385 29.877 1   16.711 ? 412  LYS   A CE   1 
ATOM   279  N NZ   . LYS   A 1 19  ? 3.983  44.159 30.527 1   18.755 ? 412  LYS   A NZ   1 
ATOM   280  H H    . LYS   A 1 19  ? 8.507  45.853 26.218 1   12.389 ? 412  LYS   A H    1 
ATOM   281  H HA   . LYS   A 1 19  ? 6.269  44.153 26.251 1   13.662 ? 412  LYS   A HA   1 
ATOM   282  H HB2  . LYS   A 1 19  ? 6.231  46.999 25.999 1   13.723 ? 412  LYS   A HB2  1 
ATOM   283  H HB3  . LYS   A 1 19  ? 4.948  46.111 25.743 1   13.729 ? 412  LYS   A HB3  1 
ATOM   284  H HG2  . LYS   A 1 19  ? 6.196  46.524 28.248 1   14.604 ? 412  LYS   A HG2  1 
ATOM   285  H HG3  . LYS   A 1 19  ? 4.794  47.099 27.819 1   14.64  ? 412  LYS   A HG3  1 
ATOM   286  H HD2  . LYS   A 1 19  ? 3.828  44.978 27.973 1   15.577 ? 412  LYS   A HD2  1 
ATOM   287  H HD3  . LYS   A 1 19  ? 5.243  44.335 28.307 1   15.55  ? 412  LYS   A HD3  1 
ATOM   288  H HE2  . LYS   A 1 19  ? 5.288  45.671 30.3   1   16.847 ? 412  LYS   A HE2  1 
ATOM   289  H HE3  . LYS   A 1 19  ? 3.795  46.088 29.993 1   16.859 ? 412  LYS   A HE3  1 
ATOM   290  H HZ1  . LYS   A 1 19  ? 4.611  43.51  30.456 1   18.078 ? 412  LYS   A HZ1  1 
ATOM   291  H HZ2  . LYS   A 1 19  ? 3.218  43.878 30.13  1   18.08  ? 412  LYS   A HZ2  1 
ATOM   292  H HZ3  . LYS   A 1 19  ? 3.82   44.32  31.404 1   18.092 ? 412  LYS   A HZ3  1 
ATOM   293  N N    . PRO   A 1 20  ? 5.864  44.232 23.677 1   16.256 ? 413  PRO   A N    1 
ATOM   294  C CA   . PRO   A 1 20  ? 5.846  44.296 22.216 1   15.605 ? 413  PRO   A CA   1 
ATOM   295  C C    . PRO   A 1 20  ? 5.667  45.724 21.702 1   14.617 ? 413  PRO   A C    1 
ATOM   296  O O    . PRO   A 1 20  ? 5.084  46.553 22.402 1   14.705 ? 413  PRO   A O    1 
ATOM   297  C CB   . PRO   A 1 20  ? 4.66   43.401 21.798 1   15.898 ? 413  PRO   A CB   1 
ATOM   298  C CG   . PRO   A 1 20  ? 4.173  42.719 23.054 1   18.591 ? 413  PRO   A CG   1 
ATOM   299  C CD   . PRO   A 1 20  ? 4.79   43.416 24.261 1   16.772 ? 413  PRO   A CD   1 
ATOM   300  H HA   . PRO   A 1 20  ? 6.68   43.923 21.864 1   15.585 ? 413  PRO   A HA   1 
ATOM   301  H HB2  . PRO   A 1 20  ? 3.946  43.937 21.401 1   16.4   ? 413  PRO   A HB2  1 
ATOM   302  H HB3  . PRO   A 1 20  ? 4.946  42.739 21.138 1   16.409 ? 413  PRO   A HB3  1 
ATOM   303  H HG2  . PRO   A 1 20  ? 3.198  42.766 23.106 1   17.526 ? 413  PRO   A HG2  1 
ATOM   304  H HG3  . PRO   A 1 20  ? 4.432  41.776 23.047 1   17.526 ? 413  PRO   A HG3  1 
ATOM   305  H HD2  . PRO   A 1 20  ? 4.136  43.981 24.717 1   17.027 ? 413  PRO   A HD2  1 
ATOM   306  H HD3  . PRO   A 1 20  ? 5.153  42.767 24.894 1   16.993 ? 413  PRO   A HD3  1 
ATOM   307  N N    . THR   A 1 21  ? 6.193  46.028 20.504 1   15.369 ? 414  THR   A N    1 
ATOM   308  C CA   . THR   A 1 21  ? 5.762  47.211 19.771 1   15.583 ? 414  THR   A CA   1 
ATOM   309  C C    . THR   A 1 21  ? 4.29   47.01  19.403 1   16.589 ? 414  THR   A C    1 
ATOM   310  O O    . THR   A 1 21  ? 3.742  45.898 19.438 1   14.871 ? 414  THR   A O    1 
ATOM   311  C CB   . THR   A 1 21  ? 6.586  47.491 18.502 1   17.508 ? 414  THR   A CB   1 
ATOM   312  O OG1  . THR   A 1 21  ? 6.33   46.448 17.555 1   14.881 ? 414  THR   A OG1  1 
ATOM   313  C CG2  . THR   A 1 21  ? 8.086  47.543 18.759 1   16.352 ? 414  THR   A CG2  1 
ATOM   314  H H    . THR   A 1 21  ? 6.825  45.481 20.136 1   15.256 ? 414  THR   A H    1 
ATOM   315  H HA   . THR   A 1 21  ? 5.835  47.987 20.366 1   16.037 ? 414  THR   A HA   1 
ATOM   316  H HB   . THR   A 1 21  ? 6.302  48.353 18.114 1   16.382 ? 414  THR   A HB   1 
ATOM   317  H HG1  . THR   A 1 21  ? 6.581  45.687 17.887 0   30     ? 414  THR   A HG1  1 
ATOM   318  H HG21 . THR   A 1 21  ? 8.541  47.855 17.958 1   16.675 ? 414  THR   A HG21 1 
ATOM   319  H HG22 . THR   A 1 21  ? 8.408  46.656 18.988 1   16.657 ? 414  THR   A HG22 1 
ATOM   320  H HG23 . THR   A 1 21  ? 8.269  48.153 19.492 1   16.664 ? 414  THR   A HG23 1 
ATOM   321  N N    . LEU   A 1 22  ? 3.656  48.131 19.089 1   16.931 ? 415  LEU   A N    1 
ATOM   322  C CA   . LEU   A 1 22  ? 2.383  48.131 18.408 1   17.349 ? 415  LEU   A CA   1 
ATOM   323  C C    . LEU   A 1 22  ? 2.631  47.655 16.985 1   17.085 ? 415  LEU   A C    1 
ATOM   324  O O    . LEU   A 1 22  ? 3.769  47.476 16.572 1   15.906 ? 415  LEU   A O    1 
ATOM   325  C CB   . LEU   A 1 22  ? 1.808  49.542 18.406 1   17.947 ? 415  LEU   A CB   1 
ATOM   326  C CG   . LEU   A 1 22  ? 1.641  50.229 19.759 1   16.295 ? 415  LEU   A CG   1 
ATOM   327  C CD1  . LEU   A 1 22  ? 1.174  51.656 19.53  1   16.598 ? 415  LEU   A CD1  1 
ATOM   328  C CD2  . LEU   A 1 22  ? 0.661  49.48  20.618 1   17.563 ? 415  LEU   A CD2  1 
ATOM   329  H H    . LEU   A 1 22  ? 4.043  48.932 19.298 1   16.928 ? 415  LEU   A H    1 
ATOM   330  H HA   . LEU   A 1 22  ? 1.763  47.511 18.869 1   17.308 ? 415  LEU   A HA   1 
ATOM   331  H HB2  . LEU   A 1 22  ? 2.388  50.106 17.845 1   17.434 ? 415  LEU   A HB2  1 
ATOM   332  H HB3  . LEU   A 1 22  ? 0.927  49.512 17.968 1   17.434 ? 415  LEU   A HB3  1 
ATOM   333  H HG   . LEU   A 1 22  ? 2.519  50.251 20.219 1   16.88  ? 415  LEU   A HG   1 
ATOM   334  H HD11 . LEU   A 1 22  ? 1.813  52.121 18.967 1   16.508 ? 415  LEU   A HD11 1 
ATOM   335  H HD12 . LEU   A 1 22  ? 1.102  52.116 20.384 1   16.508 ? 415  LEU   A HD12 1 
ATOM   336  H HD13 . LEU   A 1 22  ? 0.305  51.648 19.094 1   16.508 ? 415  LEU   A HD13 1 
ATOM   337  H HD21 . LEU   A 1 22  ? 1.047  48.629 20.887 1   17.175 ? 415  LEU   A HD21 1 
ATOM   338  H HD22 . LEU   A 1 22  ? -0.155 49.319 20.116 1   17.175 ? 415  LEU   A HD22 1 
ATOM   339  H HD23 . LEU   A 1 22  ? 0.455  50.005 21.41  1   17.175 ? 415  LEU   A HD23 1 
ATOM   340  N N    . SER   A 1 23  ? 1.545  47.498 16.237 1   18.311 ? 416  SER   A N    1 
ATOM   341  C CA   . SER   A 1 23  ? 1.629  46.928 14.904 1   20.374 ? 416  SER   A CA   1 
ATOM   342  C C    . SER   A 1 23  ? 2.427  47.832 13.968 1   20.573 ? 416  SER   A C    1 
ATOM   343  O O    . SER   A 1 23  ? 2.923  47.36  12.956 1   21.139 ? 416  SER   A O    1 
ATOM   344  C CB   . SER   A 1 23  ? 0.227  46.61  14.364 1   20.997 ? 416  SER   A CB   1 
ATOM   345  O OG   . SER   A 1 23  ? -0.594 47.771 14.357 1   25.492 ? 416  SER   A OG   1 
ATOM   346  H H    . SER   A 1 23  ? 0.727  47.744 16.562 1   18.447 ? 416  SER   A H    1 
ATOM   347  H HA   . SER   A 1 23  ? 2.122  46.071 14.981 1   20.107 ? 416  SER   A HA   1 
ATOM   348  H HB2  . SER   A 1 23  ? 0.302  46.261 13.456 1   21.895 ? 416  SER   A HB2  1 
ATOM   349  H HB3  . SER   A 1 23  ? -0.186 45.923 14.921 1   21.859 ? 416  SER   A HB3  1 
ATOM   350  H HG   . SER   A 1 23  ? -1.357 47.551 14.067 0   30     ? 416  SER   A HG   1 
ATOM   351  N N    . ASP   A 1 24  ? 2.604  49.121 14.315 1   19.818 ? 417  ASP   A N    1 
ATOM   352  C CA   . ASP   A 1 24  ? 3.27   50.06  13.427 1   20.255 ? 417  ASP   A CA   1 
ATOM   353  C C    . ASP   A 1 24  ? 4.731  50.206 13.834 1   19.326 ? 417  ASP   A C    1 
ATOM   354  O O    . ASP   A 1 24  ? 5.421  51.066 13.288 1   20.991 ? 417  ASP   A O    1 
ATOM   355  C CB   . ASP   A 1 24  ? 2.569  51.416 13.396 1   21.897 ? 417  ASP   A CB   1 
ATOM   356  C CG   . ASP   A 1 24  ? 2.563  52.156 14.727 1   22.201 ? 417  ASP   A CG   1 
ATOM   357  O OD1  . ASP   A 1 24  ? 3.053  51.559 15.713 1   22.649 ? 417  ASP   A OD1  1 
ATOM   358  O OD2  . ASP   A 1 24  ? 2.056  53.304 14.776 1   23.556 ? 417  ASP   A OD2  1 
ATOM   359  H H    . ASP   A 1 24  ? 2.289  49.423 15.117 1   20.072 ? 417  ASP   A H    1 
ATOM   360  H HA   . ASP   A 1 24  ? 3.238  49.697 12.515 1   20.295 ? 417  ASP   A HA   1 
ATOM   361  H HB2  . ASP   A 1 24  ? 3.006  51.986 12.729 1   21.578 ? 417  ASP   A HB2  1 
ATOM   362  H HB3  . ASP   A 1 24  ? 1.64   51.284 13.116 1   21.58  ? 417  ASP   A HB3  1 
ATOM   363  N N    . GLY   A 1 25  ? 5.178  49.379 14.8   1   17.142 ? 418  GLY   A N    1 
ATOM   364  C CA   . GLY   A 1 25  ? 6.557  49.41  15.255 1   16.433 ? 418  GLY   A CA   1 
ATOM   365  C C    . GLY   A 1 25  ? 6.815  50.515 16.289 1   15.676 ? 418  GLY   A C    1 
ATOM   366  O O    . GLY   A 1 25  ? 7.949  50.678 16.718 1   18.149 ? 418  GLY   A O    1 
ATOM   367  H H    . GLY   A 1 25  ? 4.605  48.782 15.187 1   17.523 ? 418  GLY   A H    1 
ATOM   368  H HA2  . GLY   A 1 25  ? 6.78   48.535 15.652 1   16.435 ? 418  GLY   A HA2  1 
ATOM   369  H HA3  . GLY   A 1 25  ? 7.149  49.546 14.478 1   16.464 ? 418  GLY   A HA3  1 
ATOM   370  N N    . THR   A 1 26  ? 5.783  51.262 16.724 1   15.383 ? 419  THR   A N    1 
ATOM   371  C CA   . THR   A 1 26  ? 5.954  52.257 17.786 1   14.685 ? 419  THR   A CA   1 
ATOM   372  C C    . THR   A 1 26  ? 5.68   51.614 19.154 1   14.783 ? 419  THR   A C    1 
ATOM   373  O O    . THR   A 1 26  ? 5.285  50.453 19.237 1   13.893 ? 419  THR   A O    1 
ATOM   374  C CB   . THR   A 1 26  ? 5.082  53.499 17.544 1   14.554 ? 419  THR   A CB   1 
ATOM   375  O OG1  . THR   A 1 26  ? 3.723  53.116 17.735 1   15.486 ? 419  THR   A OG1  1 
ATOM   376  C CG2  . THR   A 1 26  ? 5.315  54.107 16.169 1   15.477 ? 419  THR   A CG2  1 
ATOM   377  H H    . THR   A 1 26  ? 4.954  51.149 16.358 1   15.328 ? 419  THR   A H    1 
ATOM   378  H HA   . THR   A 1 26  ? 6.891  52.548 17.774 1   14.836 ? 419  THR   A HA   1 
ATOM   379  H HB   . THR   A 1 26  ? 5.31   54.185 18.215 1   14.921 ? 419  THR   A HB   1 
ATOM   380  H HG1  . THR   A 1 26  ? 3.516  52.5   17.172 0   30     ? 419  THR   A HG1  1 
ATOM   381  H HG21 . THR   A 1 26  ? 4.906  54.987 16.13  1   15.206 ? 419  THR   A HG21 1 
ATOM   382  H HG22 . THR   A 1 26  ? 4.92   53.536 15.489 1   15.228 ? 419  THR   A HG22 1 
ATOM   383  H HG23 . THR   A 1 26  ? 6.27   54.188 16.007 1   15.206 ? 419  THR   A HG23 1 
ATOM   384  N N    . CYS   A 1 27  ? 5.932  52.384 20.221 1   14.121 ? 420  CYS   A N    1 
ATOM   385  C CA   . CYS   A 1 27  ? 5.709  51.967 21.59  1   14.362 ? 420  CYS   A CA   1 
ATOM   386  C C    . CYS   A 1 27  ? 4.501  52.711 22.152 1   15.28  ? 420  CYS   A C    1 
ATOM   387  O O    . CYS   A 1 27  ? 4.407  53.914 22.015 1   13.482 ? 420  CYS   A O    1 
ATOM   388  C CB   . CYS   A 1 27  ? 6.941  52.251 22.448 1   14.145 ? 420  CYS   A CB   1 
ATOM   389  S SG   . CYS   A 1 27  ? 8.388  51.258 21.994 1   13.351 ? 420  CYS   A SG   1 
ATOM   390  H H    . CYS   A 1 27  ? 6.272  53.22  20.079 1   14.339 ? 420  CYS   A H    1 
ATOM   391  H HA   . CYS   A 1 27  ? 5.514  50.997 21.595 1   14.468 ? 420  CYS   A HA   1 
ATOM   392  H HB2  . CYS   A 1 27  ? 7.177  53.201 22.366 1   14.043 ? 420  CYS   A HB2  1 
ATOM   393  H HB3  . CYS   A 1 27  ? 6.724  52.073 23.39  1   14.049 ? 420  CYS   A HB3  1 
ATOM   394  N N    . LYS   A 1 28  ? 3.608  51.993 22.823 1   17.432 ? 421  LYS   A N    1 
ATOM   395  C CA   . LYS   A 1 28  ? 2.388  52.588 23.342 1   20.746 ? 421  LYS   A CA   1 
ATOM   396  C C    . LYS   A 1 28  ? 2.712  53.832 24.17  1   19.385 ? 421  LYS   A C    1 
ATOM   397  O O    . LYS   A 1 28  ? 3.632  53.827 24.99  1   15.438 ? 421  LYS   A O    1 
ATOM   398  C CB   . LYS   A 1 28  ? 1.62   51.629 24.251 1   24.932 ? 421  LYS   A CB   1 
ATOM   399  C CG   . LYS   A 1 28  ? 0.185  52.091 24.503 1   30.858 ? 421  LYS   A CG   1 
ATOM   400  C CD   . LYS   A 1 28  ? -0.441 51.578 25.786 1   41.152 ? 421  LYS   A CD   1 
ATOM   401  C CE   . LYS   A 1 28  ? -0.916 50.16  25.711 1   46.94  ? 421  LYS   A CE   1 
ATOM   402  N NZ   . LYS   A 1 28  ? -1.4   49.726 27.03  1   51.548 ? 421  LYS   A NZ   1 
ATOM   403  H H    . LYS   A 1 28  ? 3.761  51.103 22.968 1   17.606 ? 421  LYS   A H    1 
ATOM   404  H HA   . LYS   A 1 28  ? 1.814  52.847 22.576 1   20.446 ? 421  LYS   A HA   1 
ATOM   405  H HB2  . LYS   A 1 28  ? 1.598  50.74  23.839 1   25.056 ? 421  LYS   A HB2  1 
ATOM   406  H HB3  . LYS   A 1 28  ? 2.085  51.554 25.112 1   25.138 ? 421  LYS   A HB3  1 
ATOM   407  H HG2  . LYS   A 1 28  ? 0.17   53.072 24.517 1   31.158 ? 421  LYS   A HG2  1 
ATOM   408  H HG3  . LYS   A 1 28  ? -0.368 51.801 23.745 1   31.358 ? 421  LYS   A HG3  1 
ATOM   409  H HD2  . LYS   A 1 28  ? 0.217  51.654 26.511 1   39.652 ? 421  LYS   A HD2  1 
ATOM   410  H HD3  . LYS   A 1 28  ? -1.202 52.154 26.016 1   39.704 ? 421  LYS   A HD3  1 
ATOM   411  H HE2  . LYS   A 1 28  ? -1.639 50.086 25.063 1   46.565 ? 421  LYS   A HE2  1 
ATOM   412  H HE3  . LYS   A 1 28  ? -0.186 49.581 25.429 1   46.565 ? 421  LYS   A HE3  1 
ATOM   413  H HZ1  . LYS   A 1 28  ? -2.072 50.267 27.303 1   50.008 ? 421  LYS   A HZ1  1 
ATOM   414  H HZ2  . LYS   A 1 28  ? -0.723 49.764 27.632 1   49.991 ? 421  LYS   A HZ2  1 
ATOM   415  H HZ3  . LYS   A 1 28  ? -1.705 48.874 26.978 1   50.051 ? 421  LYS   A HZ3  1 
ATOM   416  N N    . GLU   A 1 29  ? 1.949  54.897 23.958 1   17.586 ? 422  GLU   A N    1 
ATOM   417  C CA   . GLU   A 1 29  ? 2.104  56.078 24.803 1   20.091 ? 422  GLU   A CA   1 
ATOM   418  C C    . GLU   A 1 29  ? 1.522  55.808 26.18  1   17.583 ? 422  GLU   A C    1 
ATOM   419  O O    . GLU   A 1 29  ? 0.369  55.427 26.31  1   16.557 ? 422  GLU   A O    1 
ATOM   420  C CB   . GLU   A 1 29  ? 1.393  57.296 24.23  1   24.053 ? 422  GLU   A CB   1 
ATOM   421  C CG   . GLU   A 1 29  ? 2.091  57.801 22.979 1   30.282 ? 422  GLU   A CG   1 
ATOM   422  C CD   . GLU   A 1 29  ? 1.279  58.907 22.332 1   38.539 ? 422  GLU   A CD   1 
ATOM   423  O OE1  . GLU   A 1 29  ? 0.854  59.857 23.057 1   38.679 ? 422  GLU   A OE1  1 
ATOM   424  O OE2  . GLU   A 1 29  ? 1.083  58.77  21.098 1   42.286 ? 422  GLU   A OE2  1 
ATOM   425  H H    . GLU   A 1 29  ? 1.326  54.9   23.289 1   18.605 ? 422  GLU   A H    1 
ATOM   426  H HA   . GLU   A 1 29  ? 3.07   56.28  24.889 1   19.695 ? 422  GLU   A HA   1 
ATOM   427  H HB2  . GLU   A 1 29  ? 0.466  57.057 24.019 1   24.392 ? 422  GLU   A HB2  1 
ATOM   428  H HB3  . GLU   A 1 29  ? 1.375  58.005 24.907 1   24.356 ? 422  GLU   A HB3  1 
ATOM   429  H HG2  . GLU   A 1 29  ? 2.979  58.148 23.214 1   30.366 ? 422  GLU   A HG2  1 
ATOM   430  H HG3  . GLU   A 1 29  ? 2.201  57.064 22.341 1   30.349 ? 422  GLU   A HG3  1 
ATOM   431  N N    . GLU   A 1 30  ? 2.356  55.986 27.205 1   17.833 ? 423  GLU   A N    1 
ATOM   432  C CA   . GLU   A 1 30  ? 1.967  55.74  28.578 1   18.094 ? 423  GLU   A CA   1 
ATOM   433  C C    . GLU   A 1 30  ? 2.475  56.885 29.462 1   17.624 ? 423  GLU   A C    1 
ATOM   434  O O    . GLU   A 1 30  ? 3.453  57.541 29.126 1   13.706 ? 423  GLU   A O    1 
ATOM   435  C CB   . GLU   A 1 30  ? 2.578  54.436 29.083 1   20.485 ? 423  GLU   A CB   1 
ATOM   436  C CG   . GLU   A 1 30  ? 1.734  53.195 28.844 1   25.907 ? 423  GLU   A CG   1 
ATOM   437  C CD   . GLU   A 1 30  ? 2.415  52.046 29.55  1   30.36  ? 423  GLU   A CD   1 
ATOM   438  O OE1  . GLU   A 1 30  ? 2.398  52.001 30.81  1   34.833 ? 423  GLU   A OE1  1 
ATOM   439  O OE2  . GLU   A 1 30  ? 3.059  51.257 28.827 1   27.298 ? 423  GLU   A OE2  1 
ATOM   440  H H    . GLU   A 1 30  ? 3.207  56.273 27.04  1   17.862 ? 423  GLU   A H    1 
ATOM   441  H HA   . GLU   A 1 30  ? 0.979  55.698 28.633 1   18.341 ? 423  GLU   A HA   1 
ATOM   442  H HB2  . GLU   A 1 30  ? 3.446  54.308 28.646 1   21.057 ? 423  GLU   A HB2  1 
ATOM   443  H HB3  . GLU   A 1 30  ? 2.741  54.519 30.046 1   21.104 ? 423  GLU   A HB3  1 
ATOM   444  H HG2  . GLU   A 1 30  ? 0.833  53.322 29.211 1   25.476 ? 423  GLU   A HG2  1 
ATOM   445  H HG3  . GLU   A 1 30  ? 1.674  53.005 27.883 1   25.485 ? 423  GLU   A HG3  1 
ATOM   446  N N    . PHE   A 1 31  ? 1.83   57.064 30.627 1   18.255 ? 424  PHE   A N    1 
ATOM   447  C CA   . PHE   A 1 31  ? 2.175  58.124 31.565 1   17.913 ? 424  PHE   A CA   1 
ATOM   448  C C    . PHE   A 1 31  ? 2.367  57.533 32.955 1   18.469 ? 424  PHE   A C    1 
ATOM   449  O O    . PHE   A 1 31  ? 1.686  56.592 33.345 1   17.906 ? 424  PHE   A O    1 
ATOM   450  C CB   . PHE   A 1 31  ? 1.097  59.209 31.567 1   19.652 ? 424  PHE   A CB   1 
ATOM   451  C CG   . PHE   A 1 31  ? 0.909  59.901 30.223 1   21.527 ? 424  PHE   A CG   1 
ATOM   452  C CD1  . PHE   A 1 31  ? 0.034  59.391 29.275 1   24.945 ? 424  PHE   A CD1  1 
ATOM   453  C CD2  . PHE   A 1 31  ? 1.646  61.045 29.904 1   23.663 ? 424  PHE   A CD2  1 
ATOM   454  C CE1  . PHE   A 1 31  ? -0.111 60.012 28.032 1   27.235 ? 424  PHE   A CE1  1 
ATOM   455  C CE2  . PHE   A 1 31  ? 1.507  61.666 28.669 1   27.461 ? 424  PHE   A CE2  1 
ATOM   456  C CZ   . PHE   A 1 31  ? 0.626  61.153 27.734 1   27.692 ? 424  PHE   A CZ   1 
ATOM   457  H H    . PHE   A 1 31  ? 1.146  56.498 30.843 1   18.028 ? 424  PHE   A H    1 
ATOM   458  H HA   . PHE   A 1 31  ? 3.031  58.533 31.275 1   18.341 ? 424  PHE   A HA   1 
ATOM   459  H HB2  . PHE   A 1 31  ? 0.245  58.801 31.837 1   19.645 ? 424  PHE   A HB2  1 
ATOM   460  H HB3  . PHE   A 1 31  ? 1.336  59.884 32.241 1   19.645 ? 424  PHE   A HB3  1 
ATOM   461  H HD1  . PHE   A 1 31  ? -0.464 58.614 29.471 1   24.604 ? 424  PHE   A HD1  1 
ATOM   462  H HD2  . PHE   A 1 31  ? 2.254  61.394 30.536 1   24.001 ? 424  PHE   A HD2  1 
ATOM   463  H HE1  . PHE   A 1 31  ? -0.716 59.661 27.398 1   26.725 ? 424  PHE   A HE1  1 
ATOM   464  H HE2  . PHE   A 1 31  ? 2.007  62.443 28.473 1   26.524 ? 424  PHE   A HE2  1 
ATOM   465  H HZ   . PHE   A 1 31  ? 0.522  61.579 26.898 1   27.437 ? 424  PHE   A HZ   1 
ATOM   466  N N    . THR   A 1 32  ? 3.271  58.129 33.723 1   19.24  ? 425  THR   A N    1 
ATOM   467  C CA   . THR   A 1 32  ? 3.474  57.725 35.112 1   20.784 ? 425  THR   A CA   1 
ATOM   468  C C    . THR   A 1 32  ? 2.272  58.175 35.95  1   22.182 ? 425  THR   A C    1 
ATOM   469  O O    . THR   A 1 32  ? 1.447  58.946 35.494 1   17.606 ? 425  THR   A O    1 
ATOM   470  C CB   . THR   A 1 32  ? 4.76   58.335 35.665 1   22.106 ? 425  THR   A CB   1 
ATOM   471  O OG1  . THR   A 1 32  ? 4.616  59.743 35.749 1   21.225 ? 425  THR   A OG1  1 
ATOM   472  C CG2  . THR   A 1 32  ? 5.975  58.092 34.793 1   25.441 ? 425  THR   A CG2  1 
ATOM   473  H H    . THR   A 1 32  ? 3.767  58.817 33.384 1   19.45  ? 425  THR   A H    1 
ATOM   474  H HA   . THR   A 1 32  ? 3.545  56.746 35.15  1   20.922 ? 425  THR   A HA   1 
ATOM   475  H HB   . THR   A 1 32  ? 4.934  57.973 36.567 1   22.307 ? 425  THR   A HB   1 
ATOM   476  H HG1  . THR   A 1 32  ? 4.48   60.062 34.934 0   30     ? 425  THR   A HG1  1 
ATOM   477  H HG21 . THR   A 1 32  ? 6.783  58.258 35.308 1   24.388 ? 425  THR   A HG21 1 
ATOM   478  H HG22 . THR   A 1 32  ? 5.953  58.689 34.027 1   24.34  ? 425  THR   A HG22 1 
ATOM   479  H HG23 . THR   A 1 32  ? 5.974  57.17  34.484 1   24.388 ? 425  THR   A HG23 1 
ATOM   480  N N    . VAL   A 1 33  ? 2.222  57.744 37.218 1   26.284 ? 426  VAL   A N    1 
ATOM   481  C CA   . VAL   A 1 33  ? 1.161  58.156 38.127 1   29.547 ? 426  VAL   A CA   1 
ATOM   482  C C    . VAL   A 1 33  ? 1.079  59.685 38.215 1   29.608 ? 426  VAL   A C    1 
ATOM   483  O O    . VAL   A 1 33  ? 0.001  60.223 38.439 1   28.501 ? 426  VAL   A O    1 
ATOM   484  C CB   . VAL   A 1 33  ? 1.367  57.524 39.52  1   36.523 ? 426  VAL   A CB   1 
ATOM   485  C CG1  . VAL   A 1 33  ? 2.683  57.946 40.15  1   38.829 ? 426  VAL   A CG1  1 
ATOM   486  C CG2  . VAL   A 1 33  ? 0.219  57.842 40.469 1   40.756 ? 426  VAL   A CG2  1 
ATOM   487  H H    . VAL   A 1 33  ? 2.862  57.164 37.517 1   26.06  ? 426  VAL   A H    1 
ATOM   488  H HA   . VAL   A 1 33  ? 0.314  57.827 37.767 1   30.036 ? 426  VAL   A HA   1 
ATOM   489  H HB   . VAL   A 1 33  ? 1.392  56.546 39.395 1   36.252 ? 426  VAL   A HB   1 
ATOM   490  H HG11 . VAL   A 1 33  ? 2.543  58.74  40.694 1   38.091 ? 426  VAL   A HG11 1 
ATOM   491  H HG12 . VAL   A 1 33  ? 3.332  58.144 39.455 1   37.861 ? 426  VAL   A HG12 1 
ATOM   492  H HG13 . VAL   A 1 33  ? 3.02   57.226 40.711 1   38.072 ? 426  VAL   A HG13 1 
ATOM   493  H HG21 . VAL   A 1 33  ? 0.331  57.341 41.295 1   39.426 ? 426  VAL   A HG21 1 
ATOM   494  H HG22 . VAL   A 1 33  ? -0.625 57.595 40.054 1   39.426 ? 426  VAL   A HG22 1 
ATOM   495  H HG23 . VAL   A 1 33  ? 0.216  58.791 40.666 1   39.318 ? 426  VAL   A HG23 1 
ATOM   496  N N    . ASN   A 1 34  ? 2.203  60.388 38.006 1   26.216 ? 427  ASN   A N    1 
ATOM   497  C CA   . ASN   A 1 34  ? 2.246  61.839 38.123 1   28.864 ? 427  ASN   A CA   1 
ATOM   498  C C    . ASN   A 1 34  ? 1.925  62.553 36.803 1   26.408 ? 427  ASN   A C    1 
ATOM   499  O O    . ASN   A 1 34  ? 1.963  63.783 36.738 1   28.195 ? 427  ASN   A O    1 
ATOM   500  C CB   . ASN   A 1 34  ? 3.6    62.263 38.685 1   32.762 ? 427  ASN   A CB   1 
ATOM   501  C CG   . ASN   A 1 34  ? 3.638  63.719 39.08  1   39.015 ? 427  ASN   A CG   1 
ATOM   502  O OD1  . ASN   A 1 34  ? 2.779  64.191 39.837 1   43.568 ? 427  ASN   A OD1  1 
ATOM   503  N ND2  . ASN   A 1 34  ? 4.631  64.441 38.581 1   42.182 ? 427  ASN   A ND2  1 
ATOM   504  H H    . ASN   A 1 34  ? 2.975  59.946 37.8   1   27.577 ? 427  ASN   A H    1 
ATOM   505  H HA   . ASN   A 1 34  ? 1.566  62.107 38.782 1   28.653 ? 427  ASN   A HA   1 
ATOM   506  H HB2  . ASN   A 1 34  ? 3.806  61.715 39.469 1   33.162 ? 427  ASN   A HB2  1 
ATOM   507  H HB3  . ASN   A 1 34  ? 4.29   62.097 38.012 1   33.239 ? 427  ASN   A HB3  1 
ATOM   508  H HD21 . ASN   A 1 34  ? 4.479  65.269 38.301 1   41.164 ? 427  ASN   A HD21 1 
ATOM   509  H HD22 . ASN   A 1 34  ? 5.447  64.096 38.529 1   41.108 ? 427  ASN   A HD22 1 
ATOM   510  N N    . GLY   A 1 35  ? 1.678  61.817 35.722 1   22.273 ? 428  GLY   A N    1 
ATOM   511  C CA   . GLY   A 1 35  ? 1.266  62.449 34.472 1   22.346 ? 428  GLY   A CA   1 
ATOM   512  C C    . GLY   A 1 35  ? 2.42   62.68  33.487 1   21.674 ? 428  GLY   A C    1 
ATOM   513  O O    . GLY   A 1 35  ? 2.203  63.19  32.391 1   24.132 ? 428  GLY   A O    1 
ATOM   514  H H    . GLY   A 1 35  ? 1.772  60.909 35.75  1   23.295 ? 428  GLY   A H    1 
ATOM   515  H HA2  . GLY   A 1 35  ? 0.588  61.877 34.042 1   22.188 ? 428  GLY   A HA2  1 
ATOM   516  H HA3  . GLY   A 1 35  ? 0.836  63.313 34.676 1   22.234 ? 428  GLY   A HA3  1 
ATOM   517  N N    . ASP   A 1 36  ? 3.64   62.265 33.842 1   19.847 ? 429  ASP   A N    1 
ATOM   518  C CA   . ASP   A 1 36  ? 4.787  62.475 32.971 1   18.227 ? 429  ASP   A CA   1 
ATOM   519  C C    . ASP   A 1 36  ? 4.858  61.342 31.955 1   16.402 ? 429  ASP   A C    1 
ATOM   520  O O    . ASP   A 1 36  ? 4.514  60.201 32.278 1   14.939 ? 429  ASP   A O    1 
ATOM   521  C CB   . ASP   A 1 36  ? 6.082  62.571 33.755 1   19.635 ? 429  ASP   A CB   1 
ATOM   522  C CG   . ASP   A 1 36  ? 6.069  63.689 34.79  1   22.313 ? 429  ASP   A CG   1 
ATOM   523  O OD1  . ASP   A 1 36  ? 5.786  64.823 34.392 1   21.56  ? 429  ASP   A OD1  1 
ATOM   524  O OD2  . ASP   A 1 36  ? 6.267  63.393 35.984 1   23.519 ? 429  ASP   A OD2  1 
ATOM   525  H H    . ASP   A 1 36  ? 3.764  61.839 34.641 1   19.943 ? 429  ASP   A H    1 
ATOM   526  H HA   . ASP   A 1 36  ? 4.661  63.325 32.497 1   18.476 ? 429  ASP   A HA   1 
ATOM   527  H HB2  . ASP   A 1 36  ? 6.245  61.72  34.214 1   19.898 ? 429  ASP   A HB2  1 
ATOM   528  H HB3  . ASP   A 1 36  ? 6.823  62.731 33.133 1   19.881 ? 429  ASP   A HB3  1 
ATOM   529  N N    . PRO   A 1 37  ? 5.309  61.607 30.703 1   15.895 ? 430  PRO   A N    1 
ATOM   530  C CA   . PRO   A 1 37  ? 5.452  60.543 29.731 1   14.515 ? 430  PRO   A CA   1 
ATOM   531  C C    . PRO   A 1 37  ? 6.423  59.494 30.236 1   12.362 ? 430  PRO   A C    1 
ATOM   532  O O    . PRO   A 1 37  ? 7.473  59.836 30.773 1   11.931 ? 430  PRO   A O    1 
ATOM   533  C CB   . PRO   A 1 37  ? 5.949  61.236 28.453 1   17.231 ? 430  PRO   A CB   1 
ATOM   534  C CG   . PRO   A 1 37  ? 5.679  62.711 28.702 1   18.484 ? 430  PRO   A CG   1 
ATOM   535  C CD   . PRO   A 1 37  ? 5.709  62.929 30.18  1   17.354 ? 430  PRO   A CD   1 
ATOM   536  H HA   . PRO   A 1 37  ? 4.577  60.132 29.566 1   14.748 ? 430  PRO   A HA   1 
ATOM   537  H HB2  . PRO   A 1 37  ? 6.903  61.074 28.315 1   16.818 ? 430  PRO   A HB2  1 
ATOM   538  H HB3  . PRO   A 1 37  ? 5.457  60.918 27.671 1   16.842 ? 430  PRO   A HB3  1 
ATOM   539  H HG2  . PRO   A 1 37  ? 6.362  63.261 28.268 1   17.932 ? 430  PRO   A HG2  1 
ATOM   540  H HG3  . PRO   A 1 37  ? 4.806  62.964 28.343 1   17.932 ? 430  PRO   A HG3  1 
ATOM   541  H HD2  . PRO   A 1 37  ? 6.604  63.171 30.49  1   17.252 ? 430  PRO   A HD2  1 
ATOM   542  H HD3  . PRO   A 1 37  ? 5.074  63.62  30.449 1   17.265 ? 430  PRO   A HD3  1 
ATOM   543  N N    . VAL   A 1 38  ? 6.062  58.227 30.045 1   11.23  ? 431  VAL   A N    1 
ATOM   544  C CA   . VAL   A 1 38  ? 6.982  57.143 30.268 1   12.101 ? 431  VAL   A CA   1 
ATOM   545  C C    . VAL   A 1 38  ? 7.975  57.14  29.129 1   11.936 ? 431  VAL   A C    1 
ATOM   546  O O    . VAL   A 1 38  ? 7.591  56.977 27.974 1   12.374 ? 431  VAL   A O    1 
ATOM   547  C CB   . VAL   A 1 38  ? 6.281  55.785 30.387 1   12.414 ? 431  VAL   A CB   1 
ATOM   548  C CG1  . VAL   A 1 38  ? 7.279  54.638 30.421 1   11.901 ? 431  VAL   A CG1  1 
ATOM   549  C CG2  . VAL   A 1 38  ? 5.415  55.755 31.636 1   13.912 ? 431  VAL   A CG2  1 
ATOM   550  H H    . VAL   A 1 38  ? 5.213  58.035 29.767 1   11.732 ? 431  VAL   A H    1 
ATOM   551  H HA   . VAL   A 1 38  ? 7.462  57.315 31.102 1   11.965 ? 431  VAL   A HA   1 
ATOM   552  H HB   . VAL   A 1 38  ? 5.702  55.677 29.597 1   12.521 ? 431  VAL   A HB   1 
ATOM   553  H HG11 . VAL   A 1 38  ? 8.055  54.897 30.945 1   12.054 ? 431  VAL   A HG11 1 
ATOM   554  H HG12 . VAL   A 1 38  ? 7.558  54.422 29.515 1   12.054 ? 431  VAL   A HG12 1 
ATOM   555  H HG13 . VAL   A 1 38  ? 6.864  53.857 30.824 1   12.07  ? 431  VAL   A HG13 1 
ATOM   556  H HG21 . VAL   A 1 38  ? 4.971  54.893 31.703 1   13.443 ? 431  VAL   A HG21 1 
ATOM   557  H HG22 . VAL   A 1 38  ? 4.746  56.458 31.585 1   13.456 ? 431  VAL   A HG22 1 
ATOM   558  H HG23 . VAL   A 1 38  ? 5.971  55.893 32.421 1   13.451 ? 431  VAL   A HG23 1 
ATOM   559  N N    . LYS   A 1 39  ? 9.259  57.261 29.48  1   12.686 ? 432  LYS   A N    1 
ATOM   560  C CA   . LYS   A 1 39  ? 10.314 57.197 28.479 1   14.525 ? 432  LYS   A CA   1 
ATOM   561  C C    . LYS   A 1 39  ? 10.519 55.756 28.011 1   14.275 ? 432  LYS   A C    1 
ATOM   562  O O    . LYS   A 1 39  ? 10.691 54.87  28.841 1   14.589 ? 432  LYS   A O    1 
ATOM   563  C CB   . LYS   A 1 39  ? 11.597 57.829 29.008 1   15.111 ? 432  LYS   A CB   1 
ATOM   564  C CG   . LYS   A 1 39  ? 11.499 59.309 29.372 1   18.068 ? 432  LYS   A CG   1 
ATOM   565  C CD   . LYS   A 1 39  ? 12.845 59.814 29.895 1   20.449 ? 432  LYS   A CD   1 
ATOM   566  C CE   . LYS   A 1 39  ? 12.724 60.613 31.143 1   26.346 ? 432  LYS   A CE   1 
ATOM   567  N NZ   . LYS   A 1 39  ? 12.025 61.889 30.97  1   31.506 ? 432  LYS   A NZ   1 
ATOM   568  H H    . LYS   A 1 39  ? 9.485  57.386 30.357 1   12.889 ? 432  LYS   A H    1 
ATOM   569  H HA   . LYS   A 1 39  ? 10.021 57.729 27.708 1   14.177 ? 432  LYS   A HA   1 
ATOM   570  H HB2  . LYS   A 1 39  ? 11.881 57.333 29.805 1   15.632 ? 432  LYS   A HB2  1 
ATOM   571  H HB3  . LYS   A 1 39  ? 12.298 57.725 28.329 1   15.607 ? 432  LYS   A HB3  1 
ATOM   572  H HG2  . LYS   A 1 39  ? 11.241 59.821 28.575 1   17.845 ? 432  LYS   A HG2  1 
ATOM   573  H HG3  . LYS   A 1 39  ? 10.809 59.427 30.06  1   17.869 ? 432  LYS   A HG3  1 
ATOM   574  H HD2  . LYS   A 1 39  ? 13.434 59.047 30.065 1   21.031 ? 432  LYS   A HD2  1 
ATOM   575  H HD3  . LYS   A 1 39  ? 13.266 60.368 29.203 1   21.136 ? 432  LYS   A HD3  1 
ATOM   576  H HE2  . LYS   A 1 39  ? 12.249 60.087 31.811 1   25.853 ? 432  LYS   A HE2  1 
ATOM   577  H HE3  . LYS   A 1 39  ? 13.616 60.793 31.489 1   25.903 ? 432  LYS   A HE3  1 
ATOM   578  H HZ1  . LYS   A 1 39  ? 11.138 61.741 30.861 1   29.714 ? 432  LYS   A HZ1  1 
ATOM   579  H HZ2  . LYS   A 1 39  ? 12.347 62.319 30.241 1   29.666 ? 432  LYS   A HZ2  1 
ATOM   580  H HZ3  . LYS   A 1 39  ? 12.151 62.408 31.701 1   29.768 ? 432  LYS   A HZ3  1 
ATOM   581  N N    . LYS   A 1 40  ? 10.5   55.539 26.674 1   13.741 ? 433  LYS   A N    1 
ATOM   582  C CA   . LYS   A 1 40  ? 10.596 54.219 26.072 1   13.236 ? 433  LYS   A CA   1 
ATOM   583  C C    . LYS   A 1 40  ? 11.662 54.203 24.991 1   13.119 ? 433  LYS   A C    1 
ATOM   584  O O    . LYS   A 1 40  ? 11.74  55.103 24.164 1   14.94  ? 433  LYS   A O    1 
ATOM   585  C CB   . LYS   A 1 40  ? 9.252  53.741 25.527 1   13.079 ? 433  LYS   A CB   1 
ATOM   586  C CG   . LYS   A 1 40  ? 8.187  53.71  26.58  1   13.162 ? 433  LYS   A CG   1 
ATOM   587  C CD   . LYS   A 1 40  ? 6.931  52.973 26.157 1   13.587 ? 433  LYS   A CD   1 
ATOM   588  C CE   . LYS   A 1 40  ? 5.975  52.946 27.305 1   13.827 ? 433  LYS   A CE   1 
ATOM   589  N NZ   . LYS   A 1 40  ? 4.853  52.105 26.96  1   14.415 ? 433  LYS   A NZ   1 
ATOM   590  H H    . LYS   A 1 40  ? 10.419 56.256 26.117 1   13.757 ? 433  LYS   A H    1 
ATOM   591  H HA   . LYS   A 1 40  ? 10.868 53.585 26.78  1   13.286 ? 433  LYS   A HA   1 
ATOM   592  H HB2  . LYS   A 1 40  ? 8.965  54.338 24.804 1   13.133 ? 433  LYS   A HB2  1 
ATOM   593  H HB3  . LYS   A 1 40  ? 9.355  52.839 25.155 1   13.133 ? 433  LYS   A HB3  1 
ATOM   594  H HG2  . LYS   A 1 40  ? 8.554  53.282 27.383 1   13.222 ? 433  LYS   A HG2  1 
ATOM   595  H HG3  . LYS   A 1 40  ? 7.951  54.634 26.813 1   13.233 ? 433  LYS   A HG3  1 
ATOM   596  H HD2  . LYS   A 1 40  ? 6.516  53.432 25.394 1   13.545 ? 433  LYS   A HD2  1 
ATOM   597  H HD3  . LYS   A 1 40  ? 7.156  52.054 25.895 1   13.549 ? 433  LYS   A HD3  1 
ATOM   598  H HE2  . LYS   A 1 40  ? 6.413  52.591 28.099 1   13.901 ? 433  LYS   A HE2  1 
ATOM   599  H HE3  . LYS   A 1 40  ? 5.658  53.847 27.498 1   13.908 ? 433  LYS   A HE3  1 
ATOM   600  H HZ1  . LYS   A 1 40  ? 5.134  51.254 26.83  1   14.237 ? 433  LYS   A HZ1  1 
ATOM   601  H HZ2  . LYS   A 1 40  ? 4.462  52.409 26.201 1   14.241 ? 433  LYS   A HZ2  1 
ATOM   602  H HZ3  . LYS   A 1 40  ? 4.247  52.118 27.629 1   14.293 ? 433  LYS   A HZ3  1 
ATOM   603  N N    . VAL   A 1 41  ? 12.471 53.155 25.027 1   13.596 ? 434  VAL   A N    1 
ATOM   604  C CA   . VAL   A 1 41  ? 13.54  52.966 24.076 1   15.376 ? 434  VAL   A CA   1 
ATOM   605  C C    . VAL   A 1 41  ? 13.23  51.681 23.348 1   15.579 ? 434  VAL   A C    1 
ATOM   606  O O    . VAL   A 1 41  ? 12.629 50.795 23.934 1   15.284 ? 434  VAL   A O    1 
ATOM   607  C CB   . VAL   A 1 41  ? 14.96  52.939 24.685 1   16.18  ? 434  VAL   A CB   1 
ATOM   608  C CG1  . VAL   A 1 41  ? 15.215 54.178 25.545 1   15.825 ? 434  VAL   A CG1  1 
ATOM   609  C CG2  . VAL   A 1 41  ? 15.26  51.667 25.46  1   18.411 ? 434  VAL   A CG2  1 
ATOM   610  H H    . VAL   A 1 41  ? 12.35  52.523 25.676 1   13.865 ? 434  VAL   A H    1 
ATOM   611  H HA   . VAL   A 1 41  ? 13.505 53.695 23.43  1   15.183 ? 434  VAL   A HA   1 
ATOM   612  H HB   . VAL   A 1 41  ? 15.593 52.975 23.93  1   16.355 ? 434  VAL   A HB   1 
ATOM   613  H HG11 . VAL   A 1 41  ? 14.645 54.15  26.332 1   15.918 ? 434  VAL   A HG11 1 
ATOM   614  H HG12 . VAL   A 1 41  ? 15.015 54.978 25.03  1   15.928 ? 434  VAL   A HG12 1 
ATOM   615  H HG13 . VAL   A 1 41  ? 16.146 54.196 25.821 1   15.936 ? 434  VAL   A HG13 1 
ATOM   616  H HG21 . VAL   A 1 41  ? 15.995 51.828 26.076 1   17.691 ? 434  VAL   A HG21 1 
ATOM   617  H HG22 . VAL   A 1 41  ? 15.507 50.959 24.841 1   17.702 ? 434  VAL   A HG22 1 
ATOM   618  H HG23 . VAL   A 1 41  ? 14.472 51.398 25.961 1   17.702 ? 434  VAL   A HG23 1 
ATOM   619  N N    . ILE   A 1 42  ? 13.691 51.581 22.09  1   16.607 ? 435  ILE   A N    1 
ATOM   620  C CA   . ILE   A 1 42  ? 13.603 50.318 21.382 1   16.479 ? 435  ILE   A CA   1 
ATOM   621  C C    . ILE   A 1 42  ? 14.72  49.422 21.873 1   16.241 ? 435  ILE   A C    1 
ATOM   622  O O    . ILE   A 1 42  ? 15.864 49.845 21.994 1   19.057 ? 435  ILE   A O    1 
ATOM   623  C CB   . ILE   A 1 42  ? 13.651 50.512 19.852 1   18.313 ? 435  ILE   A CB   1 
ATOM   624  C CG1  . ILE   A 1 42  ? 12.505 51.398 19.374 1   19.921 ? 435  ILE   A CG1  1 
ATOM   625  C CG2  . ILE   A 1 42  ? 13.658 49.161 19.133 1   18.777 ? 435  ILE   A CG2  1 
ATOM   626  C CD1  . ILE   A 1 42  ? 11.166 50.691 19.292 1   19.748 ? 435  ILE   A CD1  1 
ATOM   627  H H    . ILE   A 1 42  ? 14.065 52.305 21.675 1   16.345 ? 435  ILE   A H    1 
ATOM   628  H HA   . ILE   A 1 42  ? 12.75  49.904 21.606 1   16.77  ? 435  ILE   A HA   1 
ATOM   629  H HB   . ILE   A 1 42  ? 14.488 50.97  19.637 1   18.33  ? 435  ILE   A HB   1 
ATOM   630  H HG12 . ILE   A 1 42  ? 12.421 52.158 19.983 1   19.446 ? 435  ILE   A HG12 1 
ATOM   631  H HG13 . ILE   A 1 42  ? 12.729 51.749 18.488 1   19.492 ? 435  ILE   A HG13 1 
ATOM   632  H HG21 . ILE   A 1 42  ? 13.35  49.276 18.219 1   18.652 ? 435  ILE   A HG21 1 
ATOM   633  H HG22 . ILE   A 1 42  ? 13.068 48.542 19.596 1   18.622 ? 435  ILE   A HG22 1 
ATOM   634  H HG23 . ILE   A 1 42  ? 14.56  48.801 19.125 1   18.627 ? 435  ILE   A HG23 1 
ATOM   635  H HD11 . ILE   A 1 42  ? 11.131 50.145 18.484 1   19.776 ? 435  ILE   A HD11 1 
ATOM   636  H HD12 . ILE   A 1 42  ? 10.451 51.355 19.264 1   19.786 ? 435  ILE   A HD12 1 
ATOM   637  H HD13 . ILE   A 1 42  ? 11.046 50.12  20.074 1   19.755 ? 435  ILE   A HD13 1 
ATOM   638  N N    . CYS   A 1 43  ? 14.36  48.198 22.222 1   16.928 ? 436  CYS   A N    1 
ATOM   639  C CA   . CYS   A 1 43  ? 15.324 47.166 22.555 1   17.284 ? 436  CYS   A CA   1 
ATOM   640  C C    . CYS   A 1 43  ? 15.01  45.936 21.708 1   17.512 ? 436  CYS   A C    1 
ATOM   641  O O    . CYS   A 1 43  ? 13.888 45.425 21.76  1   16.384 ? 436  CYS   A O    1 
ATOM   642  C CB   . CYS   A 1 43  ? 15.297 46.812 24.039 1   19.287 ? 436  CYS   A CB   1 
ATOM   643  S SG   . CYS   A 1 43  ? 13.639 46.458 24.66  1   19.511 ? 436  CYS   A SG   1 
ATOM   644  H H    . CYS   A 1 43  ? 13.471 47.989 22.259 1   16.842 ? 436  CYS   A H    1 
ATOM   645  H HA   . CYS   A 1 43  ? 16.225 47.494 22.317 1   17.565 ? 436  CYS   A HA   1 
ATOM   646  H HB2  . CYS   A 1 43  ? 15.863 46.023 24.192 1   18.824 ? 436  CYS   A HB2  1 
ATOM   647  H HB3  . CYS   A 1 43  ? 15.671 47.559 24.555 1   18.83  ? 436  CYS   A HB3  1 
ATOM   648  N N    . THR   A 1 44  ? 16.011 45.48  20.947 1   16.145 ? 437  THR   A N    1 
ATOM   649  C CA   . THR   A 1 44  ? 15.895 44.233 20.212 1   17.374 ? 437  THR   A CA   1 
ATOM   650  C C    . THR   A 1 44  ? 16.216 43.075 21.141 1   17.996 ? 437  THR   A C    1 
ATOM   651  O O    . THR   A 1 44  ? 17.108 43.146 21.995 1   14.783 ? 437  THR   A O    1 
ATOM   652  C CB   . THR   A 1 44  ? 16.807 44.221 18.977 1   19.524 ? 437  THR   A CB   1 
ATOM   653  O OG1  . THR   A 1 44  ? 18.161 44.379 19.394 1   18.994 ? 437  THR   A OG1  1 
ATOM   654  C CG2  . THR   A 1 44  ? 16.453 45.325 18.014 1   20.207 ? 437  THR   A CG2  1 
ATOM   655  H H    . THR   A 1 44  ? 16.787 45.959 20.883 1   16.763 ? 437  THR   A H    1 
ATOM   656  H HA   . THR   A 1 44  ? 14.969 44.145 19.908 1   17.619 ? 437  THR   A HA   1 
ATOM   657  H HB   . THR   A 1 44  ? 16.712 43.355 18.513 1   19.137 ? 437  THR   A HB   1 
ATOM   658  H HG1  . THR   A 1 44  ? 18.263 45.126 19.801 0   30     ? 437  THR   A HG1  1 
ATOM   659  H HG21 . THR   A 1 44  ? 16.988 45.237 17.208 1   20.007 ? 437  THR   A HG21 1 
ATOM   660  H HG22 . THR   A 1 44  ? 16.632 46.186 18.427 1   20.025 ? 437  THR   A HG22 1 
ATOM   661  H HG23 . THR   A 1 44  ? 15.51  45.266 17.785 1   20.007 ? 437  THR   A HG23 1 
ATOM   662  N N    . GLY   A 1 45  ? 15.469 41.991 20.958 1   17.861 ? 438  GLY   A N    1 
ATOM   663  C CA   . GLY   A 1 45  ? 15.749 40.788 21.71  1   19.619 ? 438  GLY   A CA   1 
ATOM   664  C C    . GLY   A 1 45  ? 14.799 39.661 21.354 1   20.93  ? 438  GLY   A C    1 
ATOM   665  O O    . GLY   A 1 45  ? 13.87  39.838 20.557 1   17.751 ? 438  GLY   A O    1 
ATOM   666  H H    . GLY   A 1 45  ? 14.778 41.997 20.36  1   18.28  ? 438  GLY   A H    1 
ATOM   667  H HA2  . GLY   A 1 45  ? 16.677 40.506 21.53  1   19.451 ? 438  GLY   A HA2  1 
ATOM   668  H HA3  . GLY   A 1 45  ? 15.674 40.988 22.671 1   19.436 ? 438  GLY   A HA3  1 
ATOM   669  N N    . PRO   A 1 46  ? 14.985 38.489 21.991 1   23.582 ? 439  PRO   A N    1 
ATOM   670  C CA   . PRO   A 1 46  ? 14.058 37.38  21.821 1   28.426 ? 439  PRO   A CA   1 
ATOM   671  C C    . PRO   A 1 46  ? 12.676 37.742 22.327 1   34.804 ? 439  PRO   A C    1 
ATOM   672  O O    . PRO   A 1 46  ? 12.579 38.38  23.367 1   33.814 ? 439  PRO   A O    1 
ATOM   673  C CB   . PRO   A 1 46  ? 14.639 36.267 22.679 1   28.34  ? 439  PRO   A CB   1 
ATOM   674  C CG   . PRO   A 1 46  ? 15.554 36.993 23.647 1   28.234 ? 439  PRO   A CG   1 
ATOM   675  C CD   . PRO   A 1 46  ? 16.086 38.187 22.917 1   24.77  ? 439  PRO   A CD   1 
ATOM   676  H HA   . PRO   A 1 46  ? 14.02  37.112 20.881 1   28.6   ? 439  PRO   A HA   1 
ATOM   677  H HB2  . PRO   A 1 46  ? 13.935 35.787 23.156 1   28.371 ? 439  PRO   A HB2  1 
ATOM   678  H HB3  . PRO   A 1 46  ? 15.142 35.633 22.132 1   28.342 ? 439  PRO   A HB3  1 
ATOM   679  H HG2  . PRO   A 1 46  ? 15.059 37.275 24.442 1   27.427 ? 439  PRO   A HG2  1 
ATOM   680  H HG3  . PRO   A 1 46  ? 16.289 36.412 23.927 1   27.421 ? 439  PRO   A HG3  1 
ATOM   681  H HD2  . PRO   A 1 46  ? 16.249 38.933 23.525 1   25.145 ? 439  PRO   A HD2  1 
ATOM   682  H HD3  . PRO   A 1 46  ? 16.905 37.976 22.43  1   25.203 ? 439  PRO   A HD3  1 
ATOM   683  N N    . ASN   A 1 47  ? 11.637 37.339 21.595 1   41.548 ? 440  ASN   A N    1 
ATOM   684  C CA   . ASN   A 1 47  ? 10.271 37.637 21.999 1   48.644 ? 440  ASN   A CA   1 
ATOM   685  C C    . ASN   A 1 47  ? 9.52   36.367 22.392 1   52.982 ? 440  ASN   A C    1 
ATOM   686  O O    . ASN   A 1 47  ? 8.309  36.428 22.612 1   57.946 ? 440  ASN   A O    1 
ATOM   687  C CB   . ASN   A 1 47  ? 9.478  38.378 20.924 1   50.749 ? 440  ASN   A CB   1 
ATOM   688  C CG   . ASN   A 1 47  ? 9.25   37.564 19.671 1   50.663 ? 440  ASN   A CG   1 
ATOM   689  O OD1  . ASN   A 1 47  ? 10.03  36.655 19.358 1   54.215 ? 440  ASN   A OD1  1 
ATOM   690  N ND2  . ASN   A 1 47  ? 8.216  37.915 18.916 1   51.47  ? 440  ASN   A ND2  1 
ATOM   691  H H    . ASN   A 1 47  ? 11.779 36.87  20.823 1   41.162 ? 440  ASN   A H    1 
ATOM   692  H HA   . ASN   A 1 47  ? 10.305 38.224 22.788 1   48.096 ? 440  ASN   A HA   1 
ATOM   693  H HB2  . ASN   A 1 47  ? 8.611  38.638 21.293 1   50.089 ? 440  ASN   A HB2  1 
ATOM   694  H HB3  . ASN   A 1 47  ? 9.957  39.196 20.686 1   50.049 ? 440  ASN   A HB3  1 
ATOM   695  H HD21 . ASN   A 1 47  ? 7.932  37.37  18.277 1   51.24  ? 440  ASN   A HD21 1 
ATOM   696  H HD22 . ASN   A 1 47  ? 7.811  38.693 19.05  1   51.213 ? 440  ASN   A HD22 1 
ATOM   697  N N    . ASP   A 1 48  ? 10.219 35.227 22.483 1   53.349 ? 441  ASP   A N    1 
ATOM   698  C CA   . ASP   A 1 48  ? 9.566  33.992 22.898 1   54.723 ? 441  ASP   A CA   1 
ATOM   699  C C    . ASP   A 1 48  ? 10.605 33.007 23.425 1   55.079 ? 441  ASP   A C    1 
ATOM   700  O O    . ASP   A 1 48  ? 11.507 32.596 22.694 1   53.881 ? 441  ASP   A O    1 
ATOM   701  C CB   . ASP   A 1 48  ? 8.736  33.369 21.78  1   52.675 ? 441  ASP   A CB   1 
ATOM   702  C CG   . ASP   A 1 48  ? 7.721  32.327 22.234 1   50.748 ? 441  ASP   A CG   1 
ATOM   703  O OD1  . ASP   A 1 48  ? 7.566  32.14  23.46  1   46.903 ? 441  ASP   A OD1  1 
ATOM   704  O OD2  . ASP   A 1 48  ? 7.067  31.727 21.363 1   47.863 ? 441  ASP   A OD2  1 
ATOM   705  H H    . ASP   A 1 48  ? 11.112 35.214 22.288 1   53.319 ? 441  ASP   A H    1 
ATOM   706  H HA   . ASP   A 1 48  ? 8.948  34.211 23.631 1   54.105 ? 441  ASP   A HA   1 
ATOM   707  H HB2  . ASP   A 1 48  ? 8.251  34.079 21.31  1   52.711 ? 441  ASP   A HB2  1 
ATOM   708  H HB3  . ASP   A 1 48  ? 9.342  32.944 21.137 1   52.705 ? 441  ASP   A HB3  1 
ATOM   709  N N    . THR   A 1 49  ? 10.449 32.631 24.702 1   55.476 ? 442  THR   A N    1 
ATOM   710  C CA   . THR   A 1 49  ? 11.355 31.709 25.374 1   56.378 ? 442  THR   A CA   1 
ATOM   711  C C    . THR   A 1 49  ? 10.621 30.417 25.749 1   55.678 ? 442  THR   A C    1 
ATOM   712  O O    . THR   A 1 49  ? 11.084 29.681 26.624 1   55.393 ? 442  THR   A O    1 
ATOM   713  C CB   . THR   A 1 49  ? 11.976 32.391 26.599 1   54.856 ? 442  THR   A CB   1 
ATOM   714  O OG1  . THR   A 1 49  ? 10.899 32.81  27.433 1   59.262 ? 442  THR   A OG1  1 
ATOM   715  C CG2  . THR   A 1 49  ? 12.835 33.591 26.236 1   52.741 ? 442  THR   A CG2  1 
ATOM   716  H H    . THR   A 1 49  ? 9.743  32.965 25.177 1   55.564 ? 442  THR   A H    1 
ATOM   717  H HA   . THR   A 1 49  ? 12.079 31.482 24.752 1   55.776 ? 442  THR   A HA   1 
ATOM   718  H HB   . THR   A 1 49  ? 12.533 31.742 27.091 1   55.562 ? 442  THR   A HB   1 
ATOM   719  H HG1  . THR   A 1 49  ? 10.424 33.348 27.056 0   30     ? 442  THR   A HG1  1 
ATOM   720  H HG21 . THR   A 1 49  ? 13.266 33.936 27.037 1   53.36  ? 442  THR   A HG21 1 
ATOM   721  H HG22 . THR   A 1 49  ? 12.277 34.285 25.846 1   53.368 ? 442  THR   A HG22 1 
ATOM   722  H HG23 . THR   A 1 49  ? 13.514 33.323 25.595 1   53.36  ? 442  THR   A HG23 1 
ATOM   723  N N    . SER   A 1 50  ? 9.501  30.117 25.07  1   52.789 ? 443  SER   A N    1 
ATOM   724  C CA   . SER   A 1 50  ? 8.774  28.881 25.319 1   50.796 ? 443  SER   A CA   1 
ATOM   725  C C    . SER   A 1 50  ? 9.506  27.737 24.617 1   47.577 ? 443  SER   A C    1 
ATOM   726  O O    . SER   A 1 50  ? 9.862  27.862 23.447 1   46.896 ? 443  SER   A O    1 
ATOM   727  C CB   . SER   A 1 50  ? 7.334  28.987 24.88  1   52.546 ? 443  SER   A CB   1 
ATOM   728  O OG   . SER   A 1 50  ? 7.235  29.326 23.505 1   53.936 ? 443  SER   A OG   1 
ATOM   729  H H    . SER   A 1 50  ? 9.186  30.693 24.435 1   53.05  ? 443  SER   A H    1 
ATOM   730  H HA   . SER   A 1 50  ? 8.785  28.711 26.292 1   50.874 ? 443  SER   A HA   1 
ATOM   731  H HB2  . SER   A 1 50  ? 6.887  28.134 25.036 1   52.469 ? 443  SER   A HB2  1 
ATOM   732  H HB3  . SER   A 1 50  ? 6.884  29.669 25.414 1   52.469 ? 443  SER   A HB3  1 
ATOM   733  H HG   . SER   A 1 50  ? 6.425  29.388 23.286 0   30     ? 443  SER   A HG   1 
ATOM   734  N N    . PRO   A 1 51  ? 9.833  26.626 25.319 1   47.959 ? 444  PRO   A N    1 
ATOM   735  C CA   . PRO   A 1 51  ? 10.431 25.461 24.673 1   48.271 ? 444  PRO   A CA   1 
ATOM   736  C C    . PRO   A 1 51  ? 9.635  24.941 23.475 1   46.389 ? 444  PRO   A C    1 
ATOM   737  O O    . PRO   A 1 51  ? 8.437  24.701 23.585 1   44.467 ? 444  PRO   A O    1 
ATOM   738  C CB   . PRO   A 1 51  ? 10.529 24.45  25.814 1   47.548 ? 444  PRO   A CB   1 
ATOM   739  C CG   . PRO   A 1 51  ? 10.671 25.343 27.043 1   45.046 ? 444  PRO   A CG   1 
ATOM   740  C CD   . PRO   A 1 51  ? 9.738  26.473 26.783 1   47.582 ? 444  PRO   A CD   1 
ATOM   741  H HA   . PRO   A 1 51  ? 11.333 25.693 24.378 1   47.73  ? 444  PRO   A HA   1 
ATOM   742  H HB2  . PRO   A 1 51  ? 9.722  23.902 25.869 1   47.129 ? 444  PRO   A HB2  1 
ATOM   743  H HB3  . PRO   A 1 51  ? 11.309 23.872 25.706 1   47.132 ? 444  PRO   A HB3  1 
ATOM   744  H HG2  . PRO   A 1 51  ? 10.417 24.864 27.857 1   46.172 ? 444  PRO   A HG2  1 
ATOM   745  H HG3  . PRO   A 1 51  ? 11.59  25.667 27.137 1   46.172 ? 444  PRO   A HG3  1 
ATOM   746  H HD2  . PRO   A 1 51  ? 8.825  26.255 27.053 1   47.096 ? 444  PRO   A HD2  1 
ATOM   747  H HD3  . PRO   A 1 51  ? 10.029 27.285 27.24  1   47.163 ? 444  PRO   A HD3  1 
ATOM   748  N N    . GLY   A 1 52  ? 10.307 24.801 22.324 1   47.16  ? 445  GLY   A N    1 
ATOM   749  C CA   . GLY   A 1 52  ? 9.678  24.29  21.112 1   54.207 ? 445  GLY   A CA   1 
ATOM   750  C C    . GLY   A 1 52  ? 9.316  25.389 20.116 1   53.879 ? 445  GLY   A C    1 
ATOM   751  O O    . GLY   A 1 52  ? 9.281  25.146 18.913 1   56.835 ? 445  GLY   A O    1 
ATOM   752  H H    . GLY   A 1 52  ? 11.191 25.032 22.293 1   48.466 ? 445  GLY   A H    1 
ATOM   753  H HA2  . GLY   A 1 52  ? 10.297 23.664 20.675 1   52.35  ? 445  GLY   A HA2  1 
ATOM   754  H HA3  . GLY   A 1 52  ? 8.866  23.787 21.354 1   52.283 ? 445  GLY   A HA3  1 
ATOM   755  N N    . SER   A 1 53  ? 9.037  26.596 20.617 1   54.317 ? 446  SER   A N    1 
ATOM   756  C CA   . SER   A 1 53  ? 8.698  27.705 19.747 1   56.513 ? 446  SER   A CA   1 
ATOM   757  C C    . SER   A 1 53  ? 9.979  28.293 19.148 1   50.178 ? 446  SER   A C    1 
ATOM   758  O O    . SER   A 1 53  ? 11.002 28.343 19.821 1   45.29  ? 446  SER   A O    1 
ATOM   759  C CB   . SER   A 1 53  ? 7.885  28.722 20.506 1   59.607 ? 446  SER   A CB   1 
ATOM   760  O OG   . SER   A 1 53  ? 7.354  29.697 19.622 1   65.798 ? 446  SER   A OG   1 
ATOM   761  H H    . SER   A 1 53  ? 9.054  26.731 21.52  1   54.617 ? 446  SER   A H    1 
ATOM   762  H HA   . SER   A 1 53  ? 8.14   27.354 19.011 1   55.348 ? 446  SER   A HA   1 
ATOM   763  H HB2  . SER   A 1 53  ? 7.155  28.272 20.972 1   60.287 ? 446  SER   A HB2  1 
ATOM   764  H HB3  . SER   A 1 53  ? 8.451  29.159 21.169 1   60.258 ? 446  SER   A HB3  1 
ATOM   765  H HG   . SER   A 1 53  ? 6.912  30.258 20.064 0   30     ? 446  SER   A HG   1 
ATOM   766  N N    . PRO   A 1 54  ? 9.984  28.75  17.873 1   47.26  ? 447  PRO   A N    1 
ATOM   767  C CA   . PRO   A 1 54  ? 11.182 29.339 17.286 1   49.543 ? 447  PRO   A CA   1 
ATOM   768  C C    . PRO   A 1 54  ? 11.534 30.71  17.875 1   50.004 ? 447  PRO   A C    1 
ATOM   769  O O    . PRO   A 1 54  ? 10.662 31.567 18.028 1   41.328 ? 447  PRO   A O    1 
ATOM   770  C CB   . PRO   A 1 54  ? 10.866 29.428 15.789 1   53.207 ? 447  PRO   A CB   1 
ATOM   771  C CG   . PRO   A 1 54  ? 9.453  28.879 15.611 1   53.522 ? 447  PRO   A CG   1 
ATOM   772  C CD   . PRO   A 1 54  ? 8.826  28.768 16.965 1   49.598 ? 447  PRO   A CD   1 
ATOM   773  H HA   . PRO   A 1 54  ? 11.933 28.728 17.416 1   49.755 ? 447  PRO   A HA   1 
ATOM   774  H HB2  . PRO   A 1 54  ? 10.915 30.354 15.481 1   52.486 ? 447  PRO   A HB2  1 
ATOM   775  H HB3  . PRO   A 1 54  ? 11.506 28.902 15.272 1   52.442 ? 447  PRO   A HB3  1 
ATOM   776  H HG2  . PRO   A 1 54  ? 8.925  29.477 15.045 1   52.52  ? 447  PRO   A HG2  1 
ATOM   777  H HG3  . PRO   A 1 54  ? 9.483  28     15.182 1   52.52  ? 447  PRO   A HG3  1 
ATOM   778  H HD2  . PRO   A 1 54  ? 8.25   29.534 17.152 1   49.986 ? 447  PRO   A HD2  1 
ATOM   779  H HD3  . PRO   A 1 54  ? 8.307  27.946 17.043 1   49.989 ? 447  PRO   A HD3  1 
ATOM   780  N N    . ARG   A 1 55  ? 12.824 30.899 18.208 1   46.738 ? 448  ARG   A N    1 
ATOM   781  C CA   . ARG   A 1 55  ? 13.329 32.172 18.703 1   44.436 ? 448  ARG   A CA   1 
ATOM   782  C C    . ARG   A 1 55  ? 13.461 33.133 17.524 1   45.133 ? 448  ARG   A C    1 
ATOM   783  O O    . ARG   A 1 55  ? 13.942 32.763 16.455 1   45.549 ? 448  ARG   A O    1 
ATOM   784  C CB   . ARG   A 1 55  ? 14.669 32.023 19.439 1   44.585 ? 448  ARG   A CB   1 
ATOM   785  H H    . ARG   A 1 55  ? 13.41  30.203 18.117 1   46.984 ? 448  ARG   A H    1 
ATOM   786  H HA   . ARG   A 1 55  ? 12.666 32.539 19.341 1   45.045 ? 448  ARG   A HA   1 
ATOM   787  H HB2  . ARG   A 1 55  ? 15.399 32.132 18.771 0   30     ? 448  ARG   A HB2  1 
ATOM   788  H HB3  . ARG   A 1 55  ? 14.486 31.791 20.354 0   30     ? 448  ARG   A HB3  1 
ATOM   789  N N    . HIS   A 1 56  ? 12.994 34.367 17.731 1   45.573 ? 449  HIS   A N    1 
ATOM   790  C CA   . HIS   A 1 56  ? 13.158 35.455 16.777 1   47.317 ? 449  HIS   A CA   1 
ATOM   791  C C    . HIS   A 1 56  ? 13.605 36.702 17.539 1   36.762 ? 449  HIS   A C    1 
ATOM   792  O O    . HIS   A 1 56  ? 12.991 37.051 18.545 1   33.872 ? 449  HIS   A O    1 
ATOM   793  C CB   . HIS   A 1 56  ? 11.842 35.729 16.03  1   54.873 ? 449  HIS   A CB   1 
ATOM   794  C CG   . HIS   A 1 56  ? 11.297 34.557 15.271 1   64.515 ? 449  HIS   A CG   1 
ATOM   795  N ND1  . HIS   A 1 56  ? 11.924 34.044 14.153 1   66.439 ? 449  HIS   A ND1  1 
ATOM   796  C CD2  . HIS   A 1 56  ? 10.213 33.785 15.474 1   66.816 ? 449  HIS   A CD2  1 
ATOM   797  C CE1  . HIS   A 1 56  ? 11.235 33.005 13.699 1   64.492 ? 449  HIS   A CE1  1 
ATOM   798  N NE2  . HIS   A 1 56  ? 10.193 32.829 14.487 1   68.469 ? 449  HIS   A NE2  1 
ATOM   799  H H    . HIS   A 1 56  ? 12.547 34.541 18.509 1   45.774 ? 449  HIS   A H    1 
ATOM   800  H HA   . HIS   A 1 56  ? 13.862 35.213 16.127 1   45.827 ? 449  HIS   A HA   1 
ATOM   801  H HB2  . HIS   A 1 56  ? 11.169 36.024 16.681 1   55.106 ? 449  HIS   A HB2  1 
ATOM   802  H HB3  . HIS   A 1 56  ? 11.988 36.471 15.403 1   55.106 ? 449  HIS   A HB3  1 
ATOM   803  H HD1  . HIS   A 1 56  ? 12.627 34.383 13.804 0   30     ? 449  HIS   A HD1  1 
ATOM   804  H HD2  . HIS   A 1 56  ? 9.583  33.876 16.161 1   66.567 ? 449  HIS   A HD2  1 
ATOM   805  H HE1  . HIS   A 1 56  ? 11.452 32.487 12.943 1   65.824 ? 449  HIS   A HE1  1 
ATOM   806  H HE2  . HIS   A 1 56  ? 9.558  32.212 14.403 0   30     ? 449  HIS   A HE2  1 
ATOM   807  N N    . THR   A 1 57  ? 14.673 37.36  17.062 1   31.563 ? 450  THR   A N    1 
ATOM   808  C CA   . THR   A 1 57  ? 15.131 38.612 17.656 1   29.508 ? 450  THR   A CA   1 
ATOM   809  C C    . THR   A 1 57  ? 14.371 39.753 16.991 1   28.31  ? 450  THR   A C    1 
ATOM   810  O O    . THR   A 1 57  ? 14.512 39.947 15.782 1   26.337 ? 450  THR   A O    1 
ATOM   811  C CB   . THR   A 1 57  ? 16.635 38.808 17.486 1   29.837 ? 450  THR   A CB   1 
ATOM   812  O OG1  . THR   A 1 57  ? 17.216 37.771 18.265 1   29     ? 450  THR   A OG1  1 
ATOM   813  C CG2  . THR   A 1 57  ? 17.097 40.16  17.997 1   29.755 ? 450  THR   A CG2  1 
ATOM   814  H H    . THR   A 1 57  ? 15.129 37.02  16.347 1   32.429 ? 450  THR   A H    1 
ATOM   815  H HA   . THR   A 1 57  ? 14.924 38.601 18.614 1   29.572 ? 450  THR   A HA   1 
ATOM   816  H HB   . THR   A 1 57  ? 16.891 38.696 16.539 1   29.597 ? 450  THR   A HB   1 
ATOM   817  H HG1  . THR   A 1 57  ? 16.99  37.89  19.102 0   30     ? 450  THR   A HG1  1 
ATOM   818  H HG21 . THR   A 1 57  ? 18.041 40.115 18.225 1   29.768 ? 450  THR   A HG21 1 
ATOM   819  H HG22 . THR   A 1 57  ? 16.585 40.401 18.787 1   29.767 ? 450  THR   A HG22 1 
ATOM   820  H HG23 . THR   A 1 57  ? 16.964 40.832 17.307 1   29.768 ? 450  THR   A HG23 1 
ATOM   821  N N    . VAL   A 1 58  ? 13.547 40.468 17.768 1   23.361 ? 451  VAL   A N    1 
ATOM   822  C CA   . VAL   A 1 58  ? 12.678 41.49  17.201 1   22.203 ? 451  VAL   A CA   1 
ATOM   823  C C    . VAL   A 1 58  ? 12.811 42.769 18.022 1   19.697 ? 451  VAL   A C    1 
ATOM   824  O O    . VAL   A 1 58  ? 13.181 42.713 19.196 1   19.088 ? 451  VAL   A O    1 
ATOM   825  C CB   . VAL   A 1 58  ? 11.214 41.021 17.161 1   23.734 ? 451  VAL   A CB   1 
ATOM   826  C CG1  . VAL   A 1 58  ? 11.084 39.691 16.414 1   24.604 ? 451  VAL   A CG1  1 
ATOM   827  C CG2  . VAL   A 1 58  ? 10.61  40.919 18.556 1   25.442 ? 451  VAL   A CG2  1 
ATOM   828  H H    . VAL   A 1 58  ? 13.529 40.319 18.669 1   24.231 ? 451  VAL   A H    1 
ATOM   829  H HA   . VAL   A 1 58  ? 12.97  41.672 16.29  1   22.197 ? 451  VAL   A HA   1 
ATOM   830  H HB   . VAL   A 1 58  ? 10.704 41.701 16.66  1   23.876 ? 451  VAL   A HB   1 
ATOM   831  H HG11 . VAL   A 1 58  ? 11.517 38.987 16.925 1   24.341 ? 451  VAL   A HG11 1 
ATOM   832  H HG12 . VAL   A 1 58  ? 11.508 39.765 15.543 1   24.345 ? 451  VAL   A HG12 1 
ATOM   833  H HG13 . VAL   A 1 58  ? 10.144 39.475 16.3   1   24.345 ? 451  VAL   A HG13 1 
ATOM   834  H HG21 . VAL   A 1 58  ? 9.85   40.314 18.538 1   24.905 ? 451  VAL   A HG21 1 
ATOM   835  H HG22 . VAL   A 1 58  ? 10.315 41.798 18.849 1   24.884 ? 451  VAL   A HG22 1 
ATOM   836  H HG23 . VAL   A 1 58  ? 11.277 40.579 19.177 1   24.863 ? 451  VAL   A HG23 1 
ATOM   837  N N    . PRO   A 1 59  ? 12.465 43.931 17.434 1   18.504 ? 452  PRO   A N    1 
ATOM   838  C CA   . PRO   A 1 59  ? 12.381 45.174 18.178 1   17.17  ? 452  PRO   A CA   1 
ATOM   839  C C    . PRO   A 1 59  ? 11.254 45.105 19.193 1   15.388 ? 452  PRO   A C    1 
ATOM   840  O O    . PRO   A 1 59  ? 10.168 44.636 18.856 1   14.46  ? 452  PRO   A O    1 
ATOM   841  C CB   . PRO   A 1 59  ? 12.083 46.212 17.112 1   17.198 ? 452  PRO   A CB   1 
ATOM   842  C CG   . PRO   A 1 59  ? 12.458 45.53  15.809 1   18.4   ? 452  PRO   A CG   1 
ATOM   843  C CD   . PRO   A 1 59  ? 12.095 44.114 16.016 1   17.935 ? 452  PRO   A CD   1 
ATOM   844  H HA   . PRO   A 1 59  ? 13.234 45.362 18.622 1   17.06  ? 452  PRO   A HA   1 
ATOM   845  H HB2  . PRO   A 1 59  ? 11.137 46.457 17.117 1   17.426 ? 452  PRO   A HB2  1 
ATOM   846  H HB3  . PRO   A 1 59  ? 12.618 47.017 17.251 1   17.45  ? 452  PRO   A HB3  1 
ATOM   847  H HG2  . PRO   A 1 59  ? 11.958 45.909 15.059 1   18.017 ? 452  PRO   A HG2  1 
ATOM   848  H HG3  . PRO   A 1 59  ? 13.416 45.619 15.63  1   18.017 ? 452  PRO   A HG3  1 
ATOM   849  H HD2  . PRO   A 1 59  ? 11.14  43.96  15.879 1   18.18  ? 452  PRO   A HD2  1 
ATOM   850  H HD3  . PRO   A 1 59  ? 12.611 43.524 15.434 1   18.22  ? 452  PRO   A HD3  1 
ATOM   851  N N    . GLN   A 1 60  ? 11.543 45.537 20.431 1   14.873 ? 453  GLN   A N    1 
ATOM   852  C CA   . GLN   A 1 60  ? 10.565 45.603 21.507 1   14.116 ? 453  GLN   A CA   1 
ATOM   853  C C    . GLN   A 1 60  ? 10.704 46.953 22.218 1   13.915 ? 453  GLN   A C    1 
ATOM   854  O O    . GLN   A 1 60  ? 11.567 47.781 21.881 1   14.521 ? 453  GLN   A O    1 
ATOM   855  C CB   . GLN   A 1 60  ? 10.804 44.44  22.467 1   16.453 ? 453  GLN   A CB   1 
ATOM   856  C CG   . GLN   A 1 60  ? 10.689 43.087 21.782 1   19.542 ? 453  GLN   A CG   1 
ATOM   857  C CD   . GLN   A 1 60  ? 10.958 41.903 22.671 1   22.982 ? 453  GLN   A CD   1 
ATOM   858  O OE1  . GLN   A 1 60  ? 10.156 41.581 23.542 1   26.438 ? 453  GLN   A OE1  1 
ATOM   859  N NE2  . GLN   A 1 60  ? 12.058 41.213 22.415 1   26.271 ? 453  GLN   A NE2  1 
ATOM   860  H H    . GLN   A 1 60  ? 12.398 45.805 20.61  1   14.858 ? 453  GLN   A H    1 
ATOM   861  H HA   . GLN   A 1 60  ? 9.655  45.535 21.12  1   14.627 ? 453  GLN   A HA   1 
ATOM   862  H HB2  . GLN   A 1 60  ? 11.698 44.526 22.859 1   16.513 ? 453  GLN   A HB2  1 
ATOM   863  H HB3  . GLN   A 1 60  ? 10.152 44.485 23.196 1   16.456 ? 453  GLN   A HB3  1 
ATOM   864  H HG2  . GLN   A 1 60  ? 9.785  42.995 21.412 1   19.517 ? 453  GLN   A HG2  1 
ATOM   865  H HG3  . GLN   A 1 60  ? 11.316 43.056 21.03  1   19.533 ? 453  GLN   A HG3  1 
ATOM   866  H HE21 . GLN   A 1 60  ? 12.465 40.774 23.071 1   25.18  ? 453  GLN   A HE21 1 
ATOM   867  H HE22 . GLN   A 1 60  ? 12.385 41.186 21.59  1   25.081 ? 453  GLN   A HE22 1 
ATOM   868  N N    . CYS   A 1 61  ? 9.817  47.184 23.176 1   12.32  ? 454  CYS   A N    1 
ATOM   869  C CA   . CYS   A 1 61  ? 9.788  48.447 23.908 1   12.427 ? 454  CYS   A CA   1 
ATOM   870  C C    . CYS   A 1 61  ? 10.279 48.207 25.326 1   12.19  ? 454  CYS   A C    1 
ATOM   871  O O    . CYS   A 1 61  ? 9.782  47.292 25.979 1   13.839 ? 454  CYS   A O    1 
ATOM   872  C CB   . CYS   A 1 61  ? 8.375  48.993 23.924 1   12.672 ? 454  CYS   A CB   1 
ATOM   873  S SG   . CYS   A 1 61  ? 7.721  49.389 22.275 1   13.377 ? 454  CYS   A SG   1 
ATOM   874  H H    . CYS   A 1 61  ? 9.199  46.543 23.382 1   12.763 ? 454  CYS   A H    1 
ATOM   875  H HA   . CYS   A 1 61  ? 10.392 49.091 23.459 1   12.425 ? 454  CYS   A HA   1 
ATOM   876  H HB2  . CYS   A 1 61  ? 7.78   48.332 24.343 1   12.741 ? 454  CYS   A HB2  1 
ATOM   877  H HB3  . CYS   A 1 61  ? 8.353  49.809 24.471 1   12.739 ? 454  CYS   A HB3  1 
ATOM   878  N N    . CYS   A 1 62  ? 11.275 48.996 25.763 1   12.283 ? 455  CYS   A N    1 
ATOM   879  C CA   . CYS   A 1 62  ? 11.925 48.864 27.067 1   12.313 ? 455  CYS   A CA   1 
ATOM   880  C C    . CYS   A 1 62  ? 11.718 50.162 27.848 1   11.042 ? 455  CYS   A C    1 
ATOM   881  O O    . CYS   A 1 62  ? 11.755 51.241 27.266 1   10.948 ? 455  CYS   A O    1 
ATOM   882  C CB   . CYS   A 1 62  ? 13.427 48.554 26.923 1   14.996 ? 455  CYS   A CB   1 
ATOM   883  S SG   . CYS   A 1 62  ? 13.729 46.764 26.753 1   23.203 ? 455  CYS   A SG   1 
ATOM   884  H H    . CYS   A 1 62  ? 11.567 49.663 25.21  1   12.27  ? 455  CYS   A H    1 
ATOM   885  H HA   . CYS   A 1 62  ? 11.487 48.128 27.557 1   12.499 ? 455  CYS   A HA   1 
ATOM   886  H HB2  . CYS   A 1 62  ? 13.783 49.014 26.131 1   15.557 ? 455  CYS   A HB2  1 
ATOM   887  H HB3  . CYS   A 1 62  ? 13.909 48.884 27.714 1   15.532 ? 455  CYS   A HB3  1 
ATOM   888  N N    . TYR   A 1 63  ? 11.569 50.056 29.173 1   10.248 ? 456  TYR   A N    1 
ATOM   889  C CA   . TYR   A 1 63  ? 11.373 51.206 30.037 1   9.775  ? 456  TYR   A CA   1 
ATOM   890  C C    . TYR   A 1 63  ? 11.498 50.742 31.496 1   8.939  ? 456  TYR   A C    1 
ATOM   891  O O    . TYR   A 1 63  ? 11.457 49.544 31.791 1   8.124  ? 456  TYR   A O    1 
ATOM   892  C CB   . TYR   A 1 63  ? 10.036 51.927 29.784 1   10.646 ? 456  TYR   A CB   1 
ATOM   893  C CG   . TYR   A 1 63  ? 8.783  51.072 29.904 1   11.543 ? 456  TYR   A CG   1 
ATOM   894  C CD1  . TYR   A 1 63  ? 8.317  50.318 28.829 1   12.547 ? 456  TYR   A CD1  1 
ATOM   895  C CD2  . TYR   A 1 63  ? 8.083  50.981 31.104 1   12.125 ? 456  TYR   A CD2  1 
ATOM   896  C CE1  . TYR   A 1 63  ? 7.178  49.534 28.944 1   13.387 ? 456  TYR   A CE1  1 
ATOM   897  C CE2  . TYR   A 1 63  ? 6.953  50.191 31.233 1   12.819 ? 456  TYR   A CE2  1 
ATOM   898  C CZ   . TYR   A 1 63  ? 6.467  49.505 30.127 1   13.568 ? 456  TYR   A CZ   1 
ATOM   899  O OH   . TYR   A 1 63  ? 5.37   48.704 30.26  1   14.601 ? 456  TYR   A OH   1 
ATOM   900  H H    . TYR   A 1 63  ? 11.591 49.225 29.553 1   10.339 ? 456  TYR   A H    1 
ATOM   901  H HA   . TYR   A 1 63  ? 12.105 51.851 29.856 1   9.871  ? 456  TYR   A HA   1 
ATOM   902  H HB2  . TYR   A 1 63  ? 9.966  52.673 30.419 1   10.637 ? 456  TYR   A HB2  1 
ATOM   903  H HB3  . TYR   A 1 63  ? 10.063 52.315 28.882 1   10.673 ? 456  TYR   A HB3  1 
ATOM   904  H HD1  . TYR   A 1 63  ? 8.769  50.36  28.002 1   12.496 ? 456  TYR   A HD1  1 
ATOM   905  H HD2  . TYR   A 1 63  ? 8.384  51.474 31.85  1   12.145 ? 456  TYR   A HD2  1 
ATOM   906  H HE1  . TYR   A 1 63  ? 6.865  49.05  28.199 1   13.21  ? 456  TYR   A HE1  1 
ATOM   907  H HE2  . TYR   A 1 63  ? 6.482  50.167 32.048 1   12.819 ? 456  TYR   A HE2  1 
ATOM   908  H HH   . TYR   A 1 63  ? 5.227  48.263 29.535 0   30     ? 456  TYR   A HH   1 
ATOM   909  N N    . GLY   A 1 64  ? 11.671 51.709 32.411 1   8.769  ? 457  GLY   A N    1 
ATOM   910  C CA   . GLY   A 1 64  ? 11.79  51.401 33.839 1   8.374  ? 457  GLY   A CA   1 
ATOM   911  C C    . GLY   A 1 64  ? 12.961 52.139 34.484 1   8.746  ? 457  GLY   A C    1 
ATOM   912  O O    . GLY   A 1 64  ? 13.634 52.944 33.841 1   8.269  ? 457  GLY   A O    1 
ATOM   913  H H    . GLY   A 1 64  ? 11.717 52.582 32.141 1   8.726  ? 457  GLY   A H    1 
ATOM   914  H HA2  . GLY   A 1 64  ? 10.955 51.653 34.292 1   8.588  ? 457  GLY   A HA2  1 
ATOM   915  H HA3  . GLY   A 1 64  ? 11.914 50.43  33.954 1   8.555  ? 457  GLY   A HA3  1 
ATOM   916  N N    . PHE   A 1 65  ? 13.237 51.814 35.754 1   8.455  ? 458  PHE   A N    1 
ATOM   917  C CA   . PHE   A 1 65  ? 14.287 52.495 36.492 1   8.314  ? 458  PHE   A CA   1 
ATOM   918  C C    . PHE   A 1 65  ? 15.581 52.544 35.665 1   9.205  ? 458  PHE   A C    1 
ATOM   919  O O    . PHE   A 1 65  ? 16.197 53.611 35.544 1   8.177  ? 458  PHE   A O    1 
ATOM   920  C CB   . PHE   A 1 65  ? 14.453 51.789 37.834 1   8.321  ? 458  PHE   A CB   1 
ATOM   921  C CG   . PHE   A 1 65  ? 15.394 52.464 38.817 1   8.445  ? 458  PHE   A CG   1 
ATOM   922  C CD1  . PHE   A 1 65  ? 16.762 52.474 38.606 1   8.28   ? 458  PHE   A CD1  1 
ATOM   923  C CD2  . PHE   A 1 65  ? 14.918 52.995 40.016 1   8.693  ? 458  PHE   A CD2  1 
ATOM   924  C CE1  . PHE   A 1 65  ? 17.623 53.07  39.515 1   9.226  ? 458  PHE   A CE1  1 
ATOM   925  C CE2  . PHE   A 1 65  ? 15.791 53.59  40.916 1   8.659  ? 458  PHE   A CE2  1 
ATOM   926  C CZ   . PHE   A 1 65  ? 17.14  53.615 40.676 1   8.236  ? 458  PHE   A CZ   1 
ATOM   927  H H    . PHE   A 1 65  ? 12.76  51.152 36.166 1   8.488  ? 458  PHE   A H    1 
ATOM   928  H HA   . PHE   A 1 65  ? 13.991 53.428 36.664 1   8.507  ? 458  PHE   A HA   1 
ATOM   929  H HB2  . PHE   A 1 65  ? 13.567 51.708 38.252 1   8.354  ? 458  PHE   A HB2  1 
ATOM   930  H HB3  . PHE   A 1 65  ? 14.78  50.881 37.663 1   8.358  ? 458  PHE   A HB3  1 
ATOM   931  H HD1  . PHE   A 1 65  ? 17.111 52.103 37.811 1   8.534  ? 458  PHE   A HD1  1 
ATOM   932  H HD2  . PHE   A 1 65  ? 13.991 52.991 40.194 1   8.622  ? 458  PHE   A HD2  1 
ATOM   933  H HE1  . PHE   A 1 65  ? 18.551 53.085 39.34  1   8.755  ? 458  PHE   A HE1  1 
ATOM   934  H HE2  . PHE   A 1 65  ? 15.453 53.967 41.71  1   8.589  ? 458  PHE   A HE2  1 
ATOM   935  H HZ   . PHE   A 1 65  ? 17.728 54.018 41.295 1   8.557  ? 458  PHE   A HZ   1 
ATOM   936  N N    . CYS   A 1 66  ? 16.017 51.388 35.138 1   9.671  ? 459  CYS   A N    1 
ATOM   937  C CA   . CYS   A 1 66  ? 17.338 51.331 34.51  1   9.981  ? 459  CYS   A CA   1 
ATOM   938  C C    . CYS   A 1 66  ? 17.338 52.069 33.175 1   10.338 ? 459  CYS   A C    1 
ATOM   939  O O    . CYS   A 1 66  ? 18.398 52.573 32.747 1   11.219 ? 459  CYS   A O    1 
ATOM   940  C CB   . CYS   A 1 66  ? 17.806 49.895 34.326 1   10.209 ? 459  CYS   A CB   1 
ATOM   941  S SG   . CYS   A 1 66  ? 18.514 49.177 35.82  1   11.288 ? 459  CYS   A SG   1 
ATOM   942  H H    . CYS   A 1 66  ? 15.498 50.636 35.171 1   9.61   ? 459  CYS   A H    1 
ATOM   943  H HA   . CYS   A 1 66  ? 17.98  51.785 35.113 1   10.016 ? 459  CYS   A HA   1 
ATOM   944  H HB2  . CYS   A 1 66  ? 17.046 49.341 34.042 1   10.324 ? 459  CYS   A HB2  1 
ATOM   945  H HB3  . CYS   A 1 66  ? 18.485 49.865 33.615 1   10.345 ? 459  CYS   A HB3  1 
ATOM   946  H HG   . CYS   A 1 66  ? 18.775 48.086 35.365 0   30     ? 459  CYS   A HG   1 
ATOM   947  N N    . ILE   A 1 67  ? 16.169 52.134 32.507 1   10.041 ? 460  ILE   A N    1 
ATOM   948  C CA   . ILE   A 1 67  ? 16.08  52.81  31.218 1   10.019 ? 460  ILE   A CA   1 
ATOM   949  C C    . ILE   A 1 67  ? 16.154 54.317 31.422 1   10.822 ? 460  ILE   A C    1 
ATOM   950  O O    . ILE   A 1 67  ? 16.887 54.987 30.698 1   10.772 ? 460  ILE   A O    1 
ATOM   951  C CB   . ILE   A 1 67  ? 14.822 52.381 30.436 1   9.907  ? 460  ILE   A CB   1 
ATOM   952  C CG1  . ILE   A 1 67  ? 14.836 50.869 30.195 1   10.687 ? 460  ILE   A CG1  1 
ATOM   953  C CG2  . ILE   A 1 67  ? 14.668 53.198 29.161 1   11.138 ? 460  ILE   A CG2  1 
ATOM   954  C CD1  . ILE   A 1 67  ? 16.066 50.303 29.493 1   10.797 ? 460  ILE   A CD1  1 
ATOM   955  H H    . ILE   A 1 67  ? 15.419 51.748 32.859 1   10.102 ? 460  ILE   A H    1 
ATOM   956  H HA   . ILE   A 1 67  ? 16.859 52.544 30.691 1   10.164 ? 460  ILE   A HA   1 
ATOM   957  H HB   . ILE   A 1 67  ? 14.05  52.576 31.003 1   10.291 ? 460  ILE   A HB   1 
ATOM   958  H HG12 . ILE   A 1 67  ? 14.741 50.419 31.059 1   10.522 ? 460  ILE   A HG12 1 
ATOM   959  H HG13 . ILE   A 1 67  ? 14.05  50.638 29.66  1   10.519 ? 460  ILE   A HG13 1 
ATOM   960  H HG21 . ILE   A 1 67  ? 14.114 52.712 28.527 1   10.757 ? 460  ILE   A HG21 1 
ATOM   961  H HG22 . ILE   A 1 67  ? 15.542 53.358 28.767 1   10.756 ? 460  ILE   A HG22 1 
ATOM   962  H HG23 . ILE   A 1 67  ? 14.247 54.05  29.367 1   10.759 ? 460  ILE   A HG23 1 
ATOM   963  H HD11 . ILE   A 1 67  ? 16.328 50.894 28.762 1   10.764 ? 460  ILE   A HD11 1 
ATOM   964  H HD12 . ILE   A 1 67  ? 15.86  49.419 29.136 1   10.763 ? 460  ILE   A HD12 1 
ATOM   965  H HD13 . ILE   A 1 67  ? 16.802 50.231 30.13  1   10.757 ? 460  ILE   A HD13 1 
ATOM   966  N N    . ASP   A 1 68  ? 15.462 54.846 32.444 1   10.422 ? 461  ASP   A N    1 
ATOM   967  C CA   . ASP   A 1 68  ? 15.594 56.254 32.798 1   11.341 ? 461  ASP   A CA   1 
ATOM   968  C C    . ASP   A 1 68  ? 17.051 56.561 33.144 1   10.793 ? 461  ASP   A C    1 
ATOM   969  O O    . ASP   A 1 68  ? 17.587 57.615 32.776 1   11.242 ? 461  ASP   A O    1 
ATOM   970  C CB   . ASP   A 1 68  ? 14.659 56.604 33.951 1   11.07  ? 461  ASP   A CB   1 
ATOM   971  C CG   . ASP   A 1 68  ? 13.17  56.736 33.642 1   11.701 ? 461  ASP   A CG   1 
ATOM   972  O OD1  . ASP   A 1 68  ? 12.77  56.613 32.466 1   11.619 ? 461  ASP   A OD1  1 
ATOM   973  O OD2  . ASP   A 1 68  ? 12.406 56.947 34.59  1   10.827 ? 461  ASP   A OD2  1 
ATOM   974  H H    . ASP   A 1 68  ? 14.891 54.319 32.926 1   10.714 ? 461  ASP   A H    1 
ATOM   975  H HA   . ASP   A 1 68  ? 15.338 56.794 32.016 1   11.009 ? 461  ASP   A HA   1 
ATOM   976  H HB2  . ASP   A 1 68  ? 14.76  55.921 34.647 1   11.272 ? 461  ASP   A HB2  1 
ATOM   977  H HB3  . ASP   A 1 68  ? 14.955 57.458 34.331 1   11.283 ? 461  ASP   A HB3  1 
ATOM   978  N N    . LEU   A 1 69  ? 17.687 55.645 33.888 1   10.877 ? 462  LEU   A N    1 
ATOM   979  C CA   . LEU   A 1 69  ? 19.079 55.828 34.302 1   11.138 ? 462  LEU   A CA   1 
ATOM   980  C C    . LEU   A 1 69  ? 19.987 55.908 33.068 1   11.611 ? 462  LEU   A C    1 
ATOM   981  O O    . LEU   A 1 69  ? 20.821 56.812 32.961 1   10.934 ? 462  LEU   A O    1 
ATOM   982  C CB   . LEU   A 1 69  ? 19.503 54.705 35.245 1   11.312 ? 462  LEU   A CB   1 
ATOM   983  C CG   . LEU   A 1 69  ? 20.913 54.827 35.834 1   11.418 ? 462  LEU   A CG   1 
ATOM   984  C CD1  . LEU   A 1 69  ? 20.98  56.018 36.787 1   13.024 ? 462  LEU   A CD1  1 
ATOM   985  C CD2  . LEU   A 1 69  ? 21.383 53.578 36.507 1   11.776 ? 462  LEU   A CD2  1 
ATOM   986  H H    . LEU   A 1 69  ? 17.244 54.891 34.153 1   10.916 ? 462  LEU   A H    1 
ATOM   987  H HA   . LEU   A 1 69  ? 19.141 56.691 34.784 1   11.219 ? 462  LEU   A HA   1 
ATOM   988  H HB2  . LEU   A 1 69  ? 18.858 54.667 35.988 1   11.303 ? 462  LEU   A HB2  1 
ATOM   989  H HB3  . LEU   A 1 69  ? 19.445 53.853 34.755 1   11.297 ? 462  LEU   A HB3  1 
ATOM   990  H HG   . LEU   A 1 69  ? 21.539 55.011 35.087 1   11.749 ? 462  LEU   A HG   1 
ATOM   991  H HD11 . LEU   A 1 69  ? 20.938 56.845 36.279 1   12.509 ? 462  LEU   A HD11 1 
ATOM   992  H HD12 . LEU   A 1 69  ? 21.814 55.989 37.286 1   12.513 ? 462  LEU   A HD12 1 
ATOM   993  H HD13 . LEU   A 1 69  ? 20.233 55.981 37.407 1   12.514 ? 462  LEU   A HD13 1 
ATOM   994  H HD21 . LEU   A 1 69  ? 21.376 52.843 35.87  1   11.669 ? 462  LEU   A HD21 1 
ATOM   995  H HD22 . LEU   A 1 69  ? 20.792 53.367 37.25  1   11.669 ? 462  LEU   A HD22 1 
ATOM   996  H HD23 . LEU   A 1 69  ? 22.287 53.708 36.84  1   11.673 ? 462  LEU   A HD23 1 
ATOM   997  N N    . LEU   A 1 70  ? 19.805 54.958 32.137 1   11.396 ? 463  LEU   A N    1 
ATOM   998  C CA   . LEU   A 1 70  ? 20.484 54.942 30.852 1   12.461 ? 463  LEU   A CA   1 
ATOM   999  C C    . LEU   A 1 70  ? 20.344 56.276 30.126 1   13.539 ? 463  LEU   A C    1 
ATOM   1000 O O    . LEU   A 1 70  ? 21.33  56.851 29.654 1   14.139 ? 463  LEU   A O    1 
ATOM   1001 C CB   . LEU   A 1 70  ? 19.975 53.808 29.969 1   13.549 ? 463  LEU   A CB   1 
ATOM   1002 C CG   . LEU   A 1 70  ? 20.46  53.812 28.509 1   15.039 ? 463  LEU   A CG   1 
ATOM   1003 C CD1  . LEU   A 1 70  ? 21.97  53.737 28.411 1   15.153 ? 463  LEU   A CD1  1 
ATOM   1004 C CD2  . LEU   A 1 70  ? 19.817 52.649 27.789 1   15.241 ? 463  LEU   A CD2  1 
ATOM   1005 H H    . LEU   A 1 70  ? 19.224 54.277 32.323 1   11.684 ? 463  LEU   A H    1 
ATOM   1006 H HA   . LEU   A 1 70  ? 21.448 54.795 31.027 1   12.637 ? 463  LEU   A HA   1 
ATOM   1007 H HB2  . LEU   A 1 70  ? 20.244 52.955 30.382 1   13.58  ? 463  LEU   A HB2  1 
ATOM   1008 H HB3  . LEU   A 1 70  ? 18.992 53.837 29.968 1   13.585 ? 463  LEU   A HB3  1 
ATOM   1009 H HG   . LEU   A 1 70  ? 20.157 54.651 28.076 1   14.806 ? 463  LEU   A HG   1 
ATOM   1010 H HD11 . LEU   A 1 70  ? 22.36  54.559 28.753 1   15.1   ? 463  LEU   A HD11 1 
ATOM   1011 H HD12 . LEU   A 1 70  ? 22.23  53.62  27.481 1   15.115 ? 463  LEU   A HD12 1 
ATOM   1012 H HD13 . LEU   A 1 70  ? 22.293 52.984 28.934 1   15.115 ? 463  LEU   A HD13 1 
ATOM   1013 H HD21 . LEU   A 1 70  ? 18.85  52.741 27.823 1   15.181 ? 463  LEU   A HD21 1 
ATOM   1014 H HD22 . LEU   A 1 70  ? 20.077 51.817 28.218 1   15.181 ? 463  LEU   A HD22 1 
ATOM   1015 H HD23 . LEU   A 1 70  ? 20.108 52.639 26.862 1   15.181 ? 463  LEU   A HD23 1 
ATOM   1016 N N    . ILE   A 1 71  ? 19.116 56.753 29.991 1   13.799 ? 464  ILE   A N    1 
ATOM   1017 C CA   . ILE   A 1 71  ? 18.869 57.968 29.233 1   14.387 ? 464  ILE   A CA   1 
ATOM   1018 C C    . ILE   A 1 71  ? 19.635 59.133 29.858 1   16.271 ? 464  ILE   A C    1 
ATOM   1019 O O    . ILE   A 1 71  ? 20.214 59.945 29.148 1   15.284 ? 464  ILE   A O    1 
ATOM   1020 C CB   . ILE   A 1 71  ? 17.358 58.23  29.115 1   14.442 ? 464  ILE   A CB   1 
ATOM   1021 C CG1  . ILE   A 1 71  ? 16.702 57.192 28.216 1   16.274 ? 464  ILE   A CG1  1 
ATOM   1022 C CG2  . ILE   A 1 71  ? 17.028 59.651 28.648 1   15.165 ? 464  ILE   A CG2  1 
ATOM   1023 C CD1  . ILE   A 1 71  ? 15.193 57.091 28.367 1   16.582 ? 464  ILE   A CD1  1 
ATOM   1024 H H    . ILE   A 1 71  ? 18.412 56.316 30.375 1   13.876 ? 464  ILE   A H    1 
ATOM   1025 H HA   . ILE   A 1 71  ? 19.217 57.83  28.331 1   14.61  ? 464  ILE   A HA   1 
ATOM   1026 H HB   . ILE   A 1 71  ? 16.974 58.121 30.008 1   14.889 ? 464  ILE   A HB   1 
ATOM   1027 H HG12 . ILE   A 1 71  ? 16.909 57.413 27.285 1   15.89  ? 464  ILE   A HG12 1 
ATOM   1028 H HG13 . ILE   A 1 71  ? 17.095 56.317 28.408 1   15.837 ? 464  ILE   A HG13 1 
ATOM   1029 H HG21 . ILE   A 1 71  ? 16.072 59.731 28.494 1   14.979 ? 464  ILE   A HG21 1 
ATOM   1030 H HG22 . ILE   A 1 71  ? 17.503 59.84  27.822 1   14.995 ? 464  ILE   A HG22 1 
ATOM   1031 H HG23 . ILE   A 1 71  ? 17.297 60.291 29.328 1   14.97  ? 464  ILE   A HG23 1 
ATOM   1032 H HD11 . ILE   A 1 71  ? 14.964 57.008 29.312 1   16.488 ? 464  ILE   A HD11 1 
ATOM   1033 H HD12 . ILE   A 1 71  ? 14.87  56.305 27.886 1   16.488 ? 464  ILE   A HD12 1 
ATOM   1034 H HD13 . ILE   A 1 71  ? 14.77  57.89  28     1   16.479 ? 464  ILE   A HD13 1 
ATOM   1035 N N    . LYS   A 1 72  ? 19.606 59.221 31.183 1   17.284 ? 465  LYS   A N    1 
ATOM   1036 C CA   . LYS   A 1 72  ? 20.326 60.246 31.914 1   19.777 ? 465  LYS   A CA   1 
ATOM   1037 C C    . LYS   A 1 72  ? 21.836 60.133 31.674 1   19.327 ? 465  LYS   A C    1 
ATOM   1038 O O    . LYS   A 1 72  ? 22.476 61.162 31.452 1   18.824 ? 465  LYS   A O    1 
ATOM   1039 C CB   . LYS   A 1 72  ? 19.968 60.083 33.401 1   22.373 ? 465  LYS   A CB   1 
ATOM   1040 C CG   . LYS   A 1 72  ? 20.84  60.885 34.345 1   27.572 ? 465  LYS   A CG   1 
ATOM   1041 C CD   . LYS   A 1 72  ? 20.683 62.385 34.162 1   27.313 ? 465  LYS   A CD   1 
ATOM   1042 C CE   . LYS   A 1 72  ? 19.466 62.827 34.878 1   30.437 ? 465  LYS   A CE   1 
ATOM   1043 N NZ   . LYS   A 1 72  ? 19.534 64.266 35.118 1   34.311 ? 465  LYS   A NZ   1 
ATOM   1044 H H    . LYS   A 1 72  ? 19.105 58.619 31.654 1   17.582 ? 465  LYS   A H    1 
ATOM   1045 H HA   . LYS   A 1 72  ? 20.016 61.132 31.596 1   19.656 ? 465  LYS   A HA   1 
ATOM   1046 H HB2  . LYS   A 1 72  ? 19.034 60.355 33.532 1   22.839 ? 465  LYS   A HB2  1 
ATOM   1047 H HB3  . LYS   A 1 72  ? 20.039 59.136 33.643 1   22.699 ? 465  LYS   A HB3  1 
ATOM   1048 H HG2  . LYS   A 1 72  ? 20.609 60.644 35.269 1   26.268 ? 465  LYS   A HG2  1 
ATOM   1049 H HG3  . LYS   A 1 72  ? 21.779 60.639 34.198 1   26.19  ? 465  LYS   A HG3  1 
ATOM   1050 H HD2  . LYS   A 1 72  ? 21.467 62.848 34.53  1   28.113 ? 465  LYS   A HD2  1 
ATOM   1051 H HD3  . LYS   A 1 72  ? 20.601 62.605 33.209 1   27.963 ? 465  LYS   A HD3  1 
ATOM   1052 H HE2  . LYS   A 1 72  ? 18.676 62.627 34.344 1   30.529 ? 465  LYS   A HE2  1 
ATOM   1053 H HE3  . LYS   A 1 72  ? 19.386 62.367 35.733 1   30.492 ? 465  LYS   A HE3  1 
ATOM   1054 H HZ1  . LYS   A 1 72  ? 19.688 64.703 34.339 1   33.022 ? 465  LYS   A HZ1  1 
ATOM   1055 H HZ2  . LYS   A 1 72  ? 20.203 64.45  35.7   1   33.022 ? 465  LYS   A HZ2  1 
ATOM   1056 H HZ3  . LYS   A 1 72  ? 18.749 64.554 35.468 1   33.051 ? 465  LYS   A HZ3  1 
ATOM   1057 N N    . LEU   A 1 73  ? 22.409 58.913 31.784 1   18.576 ? 466  LEU   A N    1 
ATOM   1058 C CA   . LEU   A 1 73  ? 23.828 58.691 31.515 1   19.024 ? 466  LEU   A CA   1 
ATOM   1059 C C    . LEU   A 1 73  ? 24.194 59.173 30.106 1   18.745 ? 466  LEU   A C    1 
ATOM   1060 O O    . LEU   A 1 73  ? 25.211 59.845 29.933 1   18.908 ? 466  LEU   A O    1 
ATOM   1061 C CB   . LEU   A 1 73  ? 24.227 57.225 31.666 1   20.59  ? 466  LEU   A CB   1 
ATOM   1062 C CG   . LEU   A 1 73  ? 24.384 56.651 33.08  1   24.402 ? 466  LEU   A CG   1 
ATOM   1063 C CD1  . LEU   A 1 73  ? 24.563 55.13  32.995 1   24.07  ? 466  LEU   A CD1  1 
ATOM   1064 C CD2  . LEU   A 1 73  ? 25.59  57.26  33.813 1   23.782 ? 466  LEU   A CD2  1 
ATOM   1065 H H    . LEU   A 1 73  ? 21.895 58.201 32.038 1   18.86  ? 466  LEU   A H    1 
ATOM   1066 H HA   . LEU   A 1 73  ? 24.344 59.231 32.164 1   19.208 ? 466  LEU   A HA   1 
ATOM   1067 H HB2  . LEU   A 1 73  ? 23.558 56.681 31.19  1   21.007 ? 466  LEU   A HB2  1 
ATOM   1068 H HB3  . LEU   A 1 73  ? 25.078 57.093 31.189 1   21.003 ? 466  LEU   A HB3  1 
ATOM   1069 H HG   . LEU   A 1 73  ? 23.561 56.849 33.597 1   23.477 ? 466  LEU   A HG   1 
ATOM   1070 H HD11 . LEU   A 1 73  ? 23.783 54.734 32.572 1   24.144 ? 466  LEU   A HD11 1 
ATOM   1071 H HD12 . LEU   A 1 73  ? 24.666 54.764 33.889 1   24.161 ? 466  LEU   A HD12 1 
ATOM   1072 H HD13 . LEU   A 1 73  ? 25.354 54.925 32.469 1   24.161 ? 466  LEU   A HD13 1 
ATOM   1073 H HD21 . LEU   A 1 73  ? 25.645 58.21  33.619 1   23.845 ? 466  LEU   A HD21 1 
ATOM   1074 H HD22 . LEU   A 1 73  ? 26.406 56.823 33.515 1   23.934 ? 466  LEU   A HD22 1 
ATOM   1075 H HD23 . LEU   A 1 73  ? 25.486 57.132 34.771 1   23.934 ? 466  LEU   A HD23 1 
ATOM   1076 N N    . ALA   A 1 74  ? 23.403 58.762 29.102 1   19.63  ? 467  ALA   A N    1 
ATOM   1077 C CA   . ALA   A 1 74  ? 23.669 59.085 27.708 1   19.149 ? 467  ALA   A CA   1 
ATOM   1078 C C    . ALA   A 1 74  ? 23.713 60.602 27.495 1   18.852 ? 467  ALA   A C    1 
ATOM   1079 O O    . ALA   A 1 74  ? 24.623 61.099 26.845 1   18.976 ? 467  ALA   A O    1 
ATOM   1080 C CB   . ALA   A 1 74  ? 22.646 58.434 26.821 1   18.123 ? 467  ALA   A CB   1 
ATOM   1081 H H    . ALA   A 1 74  ? 22.669 58.254 29.299 1   19.292 ? 467  ALA   A H    1 
ATOM   1082 H HA   . ALA   A 1 74  ? 24.566 58.722 27.477 1   19.011 ? 467  ALA   A HA   1 
ATOM   1083 H HB1  . ALA   A 1 74  ? 22.722 57.467 26.889 1   18.426 ? 467  ALA   A HB1  1 
ATOM   1084 H HB2  . ALA   A 1 74  ? 21.754 58.706 27.096 1   18.426 ? 467  ALA   A HB2  1 
ATOM   1085 H HB3  . ALA   A 1 74  ? 22.793 58.703 25.899 1   18.434 ? 467  ALA   A HB3  1 
ATOM   1086 N N    . ARG   A 1 75  ? 22.732 61.317 28.049 1   18.789 ? 468  ARG   A N    1 
ATOM   1087 C CA   . ARG   A 1 75  ? 22.683 62.775 28.037 1   21.159 ? 468  ARG   A CA   1 
ATOM   1088 C C    . ARG   A 1 75  ? 23.923 63.362 28.717 1   22.036 ? 468  ARG   A C    1 
ATOM   1089 O O    . ARG   A 1 75  ? 24.606 64.183 28.114 1   24.512 ? 468  ARG   A O    1 
ATOM   1090 C CB   . ARG   A 1 75  ? 21.406 63.311 28.718 1   20.184 ? 468  ARG   A CB   1 
ATOM   1091 H H    . ARG   A 1 75  ? 22.048 60.867 28.456 1   19.322 ? 468  ARG   A H    1 
ATOM   1092 H HA   . ARG   A 1 75  ? 22.677 63.072 27.092 1   20.67  ? 468  ARG   A HA   1 
ATOM   1093 H HB2  . ARG   A 1 75  ? 21.655 63.905 29.436 0   30     ? 468  ARG   A HB2  1 
ATOM   1094 H HB3  . ARG   A 1 75  ? 20.626 62.94  28.226 0   30     ? 468  ARG   A HB3  1 
ATOM   1095 N N    . THR   A 1 76  ? 24.215 62.928 29.952 1   19.876 ? 469  THR   A N    1 
ATOM   1096 C CA   . THR   A 1 76  ? 25.252 63.533 30.784 1   24.525 ? 469  THR   A CA   1 
ATOM   1097 C C    . THR   A 1 76  ? 26.64  63.307 30.167 1   22.129 ? 469  THR   A C    1 
ATOM   1098 O O    . THR   A 1 76  ? 27.528 64.136 30.319 1   22.431 ? 469  THR   A O    1 
ATOM   1099 C CB   . THR   A 1 76  ? 25.227 62.94  32.196 1   25.896 ? 469  THR   A CB   1 
ATOM   1100 O OG1  . THR   A 1 76  ? 24.011 63.306 32.836 1   31.488 ? 469  THR   A OG1  1 
ATOM   1101 C CG2  . THR   A 1 76  ? 26.386 63.44  33.046 1   28.757 ? 469  THR   A CG2  1 
ATOM   1102 H H    . THR   A 1 76  ? 23.747 62.22  30.29  1   21.364 ? 469  THR   A H    1 
ATOM   1103 H HA   . THR   A 1 76  ? 25.082 64.498 30.843 1   23.333 ? 469  THR   A HA   1 
ATOM   1104 H HB   . THR   A 1 76  ? 25.278 61.957 32.136 1   27.161 ? 469  THR   A HB   1 
ATOM   1105 H HG1  . THR   A 1 76  ? 23.947 64.16  32.888 0   30     ? 469  THR   A HG1  1 
ATOM   1106 H HG21 . THR   A 1 76  ? 26.15  63.372 33.987 1   27.876 ? 469  THR   A HG21 1 
ATOM   1107 H HG22 . THR   A 1 76  ? 26.574 64.369 32.827 1   27.796 ? 469  THR   A HG22 1 
ATOM   1108 H HG23 . THR   A 1 76  ? 27.175 62.9   32.872 1   27.835 ? 469  THR   A HG23 1 
ATOM   1109 N N    . MET   A 1 77  ? 26.845 62.156 29.529 1   21.968 ? 470  MET   A N    1 
ATOM   1110 C CA   . MET   A 1 77  ? 28.154 61.792 29.011 1   23.221 ? 470  MET   A CA   1 
ATOM   1111 C C    . MET   A 1 77  ? 28.204 61.884 27.484 1   23.421 ? 470  MET   A C    1 
ATOM   1112 O O    . MET   A 1 77  ? 29.183 61.459 26.868 1   26.12  ? 470  MET   A O    1 
ATOM   1113 C CB   . MET   A 1 77  ? 28.52  60.381 29.456 1   22.669 ? 470  MET   A CB   1 
ATOM   1114 C CG   . MET   A 1 77  ? 28.804 60.285 30.926 1   26.915 ? 470  MET   A CG   1 
ATOM   1115 S SD   . MET   A 1 77  ? 28.992 58.583 31.496 1   24.87  ? 470  MET   A SD   1 
ATOM   1116 C CE   . MET   A 1 77  ? 30.426 58.114 30.518 1   30.044 ? 470  MET   A CE   1 
ATOM   1117 H H    . MET   A 1 77  ? 26.152 61.57  29.422 1   22.289 ? 470  MET   A H    1 
ATOM   1118 H HA   . MET   A 1 77  ? 28.82  62.426 29.378 1   22.899 ? 470  MET   A HA   1 
ATOM   1119 H HB2  . MET   A 1 77  ? 27.782 59.776 29.231 1   23.702 ? 470  MET   A HB2  1 
ATOM   1120 H HB3  . MET   A 1 77  ? 29.312 60.088 28.957 1   23.781 ? 470  MET   A HB3  1 
ATOM   1121 H HG2  . MET   A 1 77  ? 29.625 60.777 31.128 1   25.431 ? 470  MET   A HG2  1 
ATOM   1122 H HG3  . MET   A 1 77  ? 28.074 60.704 31.424 1   25.415 ? 470  MET   A HG3  1 
ATOM   1123 H HE1  . MET   A 1 77  ? 30.771 57.259 30.835 1   28.498 ? 470  MET   A HE1  1 
ATOM   1124 H HE2  . MET   A 1 77  ? 30.165 58.033 29.582 1   28.654 ? 470  MET   A HE2  1 
ATOM   1125 H HE3  . MET   A 1 77  ? 31.117 58.797 30.606 1   28.543 ? 470  MET   A HE3  1 
ATOM   1126 N N    . ASN   A 1 78  ? 27.135 62.389 26.872 1   22.974 ? 471  ASN   A N    1 
ATOM   1127 C CA   . ASN   A 1 78  ? 27.121 62.717 25.455 1   26.307 ? 471  ASN   A CA   1 
ATOM   1128 C C    . ASN   A 1 78  ? 27.415 61.497 24.571 1   25.166 ? 471  ASN   A C    1 
ATOM   1129 O O    . ASN   A 1 78  ? 28.188 61.593 23.625 1   28.236 ? 471  ASN   A O    1 
ATOM   1130 C CB   . ASN   A 1 78  ? 28.104 63.852 25.197 1   31.935 ? 471  ASN   A CB   1 
ATOM   1131 C CG   . ASN   A 1 78  ? 27.795 64.575 23.913 1   38.758 ? 471  ASN   A CG   1 
ATOM   1132 O OD1  . ASN   A 1 78  ? 26.651 64.986 23.679 1   40.187 ? 471  ASN   A OD1  1 
ATOM   1133 N ND2  . ASN   A 1 78  ? 28.789 64.686 23.048 1   45.385 ? 471  ASN   A ND2  1 
ATOM   1134 H H    . ASN   A 1 78  ? 26.374 62.535 27.355 1   23.75  ? 471  ASN   A H    1 
ATOM   1135 H HA   . ASN   A 1 78  ? 26.222 63.048 25.232 1   26.471 ? 471  ASN   A HA   1 
ATOM   1136 H HB2  . ASN   A 1 78  ? 28.063 64.487 25.94  1   31.893 ? 471  ASN   A HB2  1 
ATOM   1137 H HB3  . ASN   A 1 78  ? 29.012 63.491 25.158 1   31.947 ? 471  ASN   A HB3  1 
ATOM   1138 H HD21 . ASN   A 1 78  ? 28.715 65.254 22.371 1   43.158 ? 471  ASN   A HD21 1 
ATOM   1139 H HD22 . ASN   A 1 78  ? 29.516 64.185 23.133 1   43.01  ? 471  ASN   A HD22 1 
ATOM   1140 N N    . PHE   A 1 79  ? 26.782 60.352 24.837 1   21.816 ? 472  PHE   A N    1 
ATOM   1141 C CA   . PHE   A 1 79  ? 26.984 59.194 23.979 1   21.52  ? 472  PHE   A CA   1 
ATOM   1142 C C    . PHE   A 1 79  ? 25.646 58.78  23.378 1   20.943 ? 472  PHE   A C    1 
ATOM   1143 O O    . PHE   A 1 79  ? 24.602 59.08  23.953 1   20.142 ? 472  PHE   A O    1 
ATOM   1144 C CB   . PHE   A 1 79  ? 27.663 57.995 24.654 1   21.173 ? 472  PHE   A CB   1 
ATOM   1145 C CG   . PHE   A 1 79  ? 26.944 57.367 25.838 1   22.228 ? 472  PHE   A CG   1 
ATOM   1146 C CD1  . PHE   A 1 79  ? 25.922 56.446 25.652 1   24.734 ? 472  PHE   A CD1  1 
ATOM   1147 C CD2  . PHE   A 1 79  ? 27.336 57.664 27.137 1   19.846 ? 472  PHE   A CD2  1 
ATOM   1148 C CE1  . PHE   A 1 79  ? 25.297 55.85  26.744 1   24.104 ? 472  PHE   A CE1  1 
ATOM   1149 C CE2  . PHE   A 1 79  ? 26.695 57.096 28.212 1   20.413 ? 472  PHE   A CE2  1 
ATOM   1150 C CZ   . PHE   A 1 79  ? 25.691 56.176 28.018 1   22.055 ? 472  PHE   A CZ   1 
ATOM   1151 H H    . PHE   A 1 79  ? 26.218 60.289 25.554 1   22.531 ? 472  PHE   A H    1 
ATOM   1152 H HA   . PHE   A 1 79  ? 27.57  59.477 23.229 1   21.465 ? 472  PHE   A HA   1 
ATOM   1153 H HB2  . PHE   A 1 79  ? 27.798 57.301 23.972 1   21.486 ? 472  PHE   A HB2  1 
ATOM   1154 H HB3  . PHE   A 1 79  ? 28.556 58.28  24.95  1   21.474 ? 472  PHE   A HB3  1 
ATOM   1155 H HD1  . PHE   A 1 79  ? 25.658 56.214 24.776 1   23.865 ? 472  PHE   A HD1  1 
ATOM   1156 H HD2  . PHE   A 1 79  ? 28.027 58.29  27.283 1   20.57  ? 472  PHE   A HD2  1 
ATOM   1157 H HE1  . PHE   A 1 79  ? 24.596 55.233 26.609 1   23.681 ? 472  PHE   A HE1  1 
ATOM   1158 H HE2  . PHE   A 1 79  ? 26.97  57.313 29.089 1   20.704 ? 472  PHE   A HE2  1 
ATOM   1159 H HZ   . PHE   A 1 79  ? 25.257 55.787 28.76  1   22.115 ? 472  PHE   A HZ   1 
ATOM   1160 N N    . THR   A 1 80  ? 25.701 58.137 22.195 1   20.942 ? 473  THR   A N    1 
ATOM   1161 C CA   . THR   A 1 80  ? 24.551 57.49  21.583 1   20.98  ? 473  THR   A CA   1 
ATOM   1162 C C    . THR   A 1 80  ? 24.65  56.005 21.899 1   18.453 ? 473  THR   A C    1 
ATOM   1163 O O    . THR   A 1 80  ? 25.717 55.48  22.179 1   20.101 ? 473  THR   A O    1 
ATOM   1164 C CB   . THR   A 1 80  ? 24.526 57.728 20.065 1   22.673 ? 473  THR   A CB   1 
ATOM   1165 O OG1  . THR   A 1 80  ? 25.834 57.356 19.63  1   22.564 ? 473  THR   A OG1  1 
ATOM   1166 C CG2  . THR   A 1 80  ? 24.288 59.175 19.669 1   22.681 ? 473  THR   A CG2  1 
ATOM   1167 H H    . THR   A 1 80  ? 26.5   58.105 21.752 1   20.959 ? 473  THR   A H    1 
ATOM   1168 H HA   . THR   A 1 80  ? 23.728 57.852 21.979 1   20.755 ? 473  THR   A HA   1 
ATOM   1169 H HB   . THR   A 1 80  ? 23.854 57.145 19.637 1   22.483 ? 473  THR   A HB   1 
ATOM   1170 H HG1  . THR   A 1 80  ? 26.439 57.861 20.011 0   30     ? 473  THR   A HG1  1 
ATOM   1171 H HG21 . THR   A 1 80  ? 24.292 59.251 18.7   1   22.679 ? 473  THR   A HG21 1 
ATOM   1172 H HG22 . THR   A 1 80  ? 24.991 59.733 20.04  1   22.679 ? 473  THR   A HG22 1 
ATOM   1173 H HG23 . THR   A 1 80  ? 23.427 59.468 20.012 1   22.679 ? 473  THR   A HG23 1 
ATOM   1174 N N    . TYR   A 1 81  ? 23.525 55.31  21.81  1   18.544 ? 474  TYR   A N    1 
ATOM   1175 C CA   . TYR   A 1 81  ? 23.492 53.907 22.171 1   16.964 ? 474  TYR   A CA   1 
ATOM   1176 C C    . TYR   A 1 81  ? 22.417 53.172 21.38  1   15.938 ? 474  TYR   A C    1 
ATOM   1177 O O    . TYR   A 1 81  ? 21.496 53.793 20.849 1   14.903 ? 474  TYR   A O    1 
ATOM   1178 C CB   . TYR   A 1 81  ? 23.194 53.784 23.667 1   16.605 ? 474  TYR   A CB   1 
ATOM   1179 C CG   . TYR   A 1 81  ? 21.89  54.447 24.052 1   17.272 ? 474  TYR   A CG   1 
ATOM   1180 C CD1  . TYR   A 1 81  ? 20.691 53.757 23.962 1   17.361 ? 474  TYR   A CD1  1 
ATOM   1181 C CD2  . TYR   A 1 81  ? 21.861 55.758 24.511 1   18.567 ? 474  TYR   A CD2  1 
ATOM   1182 C CE1  . TYR   A 1 81  ? 19.5   54.36  24.284 1   18.447 ? 474  TYR   A CE1  1 
ATOM   1183 C CE2  . TYR   A 1 81  ? 20.673 56.384 24.821 1   18.442 ? 474  TYR   A CE2  1 
ATOM   1184 C CZ   . TYR   A 1 81  ? 19.492 55.67  24.709 1   18.657 ? 474  TYR   A CZ   1 
ATOM   1185 O OH   . TYR   A 1 81  ? 18.323 56.273 24.984 1   19.087 ? 474  TYR   A OH   1 
ATOM   1186 H H    . TYR   A 1 81  ? 22.758 55.715 21.52  1   18.175 ? 474  TYR   A H    1 
ATOM   1187 H HA   . TYR   A 1 81  ? 24.376 53.5   21.978 1   17.031 ? 474  TYR   A HA   1 
ATOM   1188 H HB2  . TYR   A 1 81  ? 23.152 52.833 23.903 1   16.764 ? 474  TYR   A HB2  1 
ATOM   1189 H HB3  . TYR   A 1 81  ? 23.929 54.199 24.173 1   16.823 ? 474  TYR   A HB3  1 
ATOM   1190 H HD1  . TYR   A 1 81  ? 20.69  52.865 23.655 1   17.596 ? 474  TYR   A HD1  1 
ATOM   1191 H HD2  . TYR   A 1 81  ? 22.667 56.246 24.565 1   18.221 ? 474  TYR   A HD2  1 
ATOM   1192 H HE1  . TYR   A 1 81  ? 18.69  53.887 24.196 1   18.231 ? 474  TYR   A HE1  1 
ATOM   1193 H HE2  . TYR   A 1 81  ? 20.664 57.28  25.111 1   18.504 ? 474  TYR   A HE2  1 
ATOM   1194 H HH   . TYR   A 1 81  ? 17.66  55.729 24.859 0   30     ? 474  TYR   A HH   1 
ATOM   1195 N N    . GLU   A 1 82  ? 22.51  51.843 21.41  1   16.605 ? 475  GLU   A N    1 
ATOM   1196 C CA   . GLU   A 1 82  ? 21.407 50.983 21.014 1   18.453 ? 475  GLU   A CA   1 
ATOM   1197 C C    . GLU   A 1 82  ? 21.314 49.843 22.022 1   15.527 ? 475  GLU   A C    1 
ATOM   1198 O O    . GLU   A 1 82  ? 22.336 49.312 22.444 1   14.055 ? 475  GLU   A O    1 
ATOM   1199 C CB   . GLU   A 1 82  ? 21.579 50.465 19.58  1   23.581 ? 475  GLU   A CB   1 
ATOM   1200 C CG   . GLU   A 1 82  ? 22.953 49.858 19.328 1   28.565 ? 475  GLU   A CG   1 
ATOM   1201 C CD   . GLU   A 1 82  ? 23.241 49.482 17.879 1   34.607 ? 475  GLU   A CD   1 
ATOM   1202 O OE1  . GLU   A 1 82  ? 22.633 50.086 16.972 1   37.384 ? 475  GLU   A OE1  1 
ATOM   1203 O OE2  . GLU   A 1 82  ? 24.049 48.556 17.671 1   38.147 ? 475  GLU   A OE2  1 
ATOM   1204 H H    . GLU   A 1 82  ? 23.289 51.456 21.692 1   16.954 ? 475  GLU   A H    1 
ATOM   1205 H HA   . GLU   A 1 82  ? 20.57  51.51  21.058 1   18.23  ? 475  GLU   A HA   1 
ATOM   1206 H HB2  . GLU   A 1 82  ? 20.892 49.789 19.403 1   23.312 ? 475  GLU   A HB2  1 
ATOM   1207 H HB3  . GLU   A 1 82  ? 21.434 51.208 18.958 1   23.36  ? 475  GLU   A HB3  1 
ATOM   1208 H HG2  . GLU   A 1 82  ? 23.64  50.494 19.621 1   28.339 ? 475  GLU   A HG2  1 
ATOM   1209 H HG3  . GLU   A 1 82  ? 23.049 49.052 19.879 1   28.342 ? 475  GLU   A HG3  1 
ATOM   1210 N N    . VAL   A 1 83  ? 20.076 49.477 22.38  1   14.974 ? 476  VAL   A N    1 
ATOM   1211 C CA   . VAL   A 1 83  ? 19.82  48.548 23.467 1   14.633 ? 476  VAL   A CA   1 
ATOM   1212 C C    . VAL   A 1 83  ? 19.374 47.214 22.885 1   14.139 ? 476  VAL   A C    1 
ATOM   1213 O O    . VAL   A 1 83  ? 18.585 47.165 21.948 1   14.013 ? 476  VAL   A O    1 
ATOM   1214 C CB   . VAL   A 1 83  ? 18.764 49.092 24.452 1   14.795 ? 476  VAL   A CB   1 
ATOM   1215 C CG1  . VAL   A 1 83  ? 18.564 48.131 25.605 1   15.766 ? 476  VAL   A CG1  1 
ATOM   1216 C CG2  . VAL   A 1 83  ? 19.121 50.468 24.993 1   14.653 ? 476  VAL   A CG2  1 
ATOM   1217 H H    . VAL   A 1 83  ? 19.362 49.82  21.923 1   15.072 ? 476  VAL   A H    1 
ATOM   1218 H HA   . VAL   A 1 83  ? 20.652 48.411 23.957 1   14.622 ? 476  VAL   A HA   1 
ATOM   1219 H HB   . VAL   A 1 83  ? 17.912 49.165 23.96  1   14.915 ? 476  VAL   A HB   1 
ATOM   1220 H HG11 . VAL   A 1 83  ? 19.427 47.806 25.91  1   15.457 ? 476  VAL   A HG11 1 
ATOM   1221 H HG12 . VAL   A 1 83  ? 18.021 47.38  25.312 1   15.46  ? 476  VAL   A HG12 1 
ATOM   1222 H HG13 . VAL   A 1 83  ? 18.114 48.587 26.336 1   15.457 ? 476  VAL   A HG13 1 
ATOM   1223 H HG21 . VAL   A 1 83  ? 18.444 50.754 25.629 1   14.695 ? 476  VAL   A HG21 1 
ATOM   1224 H HG22 . VAL   A 1 83  ? 19.163 51.105 24.26  1   14.692 ? 476  VAL   A HG22 1 
ATOM   1225 H HG23 . VAL   A 1 83  ? 19.985 50.429 25.436 1   14.672 ? 476  VAL   A HG23 1 
ATOM   1226 N N    . HIS   A 1 84  ? 19.874 46.123 23.47  1   13.709 ? 477  HIS   A N    1 
ATOM   1227 C CA   . HIS   A 1 84  ? 19.314 44.82  23.196 1   13.541 ? 477  HIS   A CA   1 
ATOM   1228 C C    . HIS   A 1 84  ? 19.202 44.054 24.503 1   12.714 ? 477  HIS   A C    1 
ATOM   1229 O O    . HIS   A 1 84  ? 19.87  44.39  25.485 1   12.102 ? 477  HIS   A O    1 
ATOM   1230 C CB   . HIS   A 1 84  ? 20.134 44.057 22.142 1   13.679 ? 477  HIS   A CB   1 
ATOM   1231 C CG   . HIS   A 1 84  ? 21.464 43.552 22.596 1   13.458 ? 477  HIS   A CG   1 
ATOM   1232 N ND1  . HIS   A 1 84  ? 22.6   44.337 22.558 1   12.343 ? 477  HIS   A ND1  1 
ATOM   1233 C CD2  . HIS   A 1 84  ? 21.842 42.359 23.078 1   12.623 ? 477  HIS   A CD2  1 
ATOM   1234 C CE1  . HIS   A 1 84  ? 23.609 43.632 23.041 1   11.925 ? 477  HIS   A CE1  1 
ATOM   1235 N NE2  . HIS   A 1 84  ? 23.179 42.431 23.364 1   12.544 ? 477  HIS   A NE2  1 
ATOM   1236 H H    . HIS   A 1 84  ? 20.579 46.194 24.047 1   13.778 ? 477  HIS   A H    1 
ATOM   1237 H HA   . HIS   A 1 84  ? 18.401 44.955 22.844 1   13.446 ? 477  HIS   A HA   1 
ATOM   1238 H HB2  . HIS   A 1 84  ? 19.602 43.296 21.827 1   13.603 ? 477  HIS   A HB2  1 
ATOM   1239 H HB3  . HIS   A 1 84  ? 20.27  44.648 21.37  1   13.598 ? 477  HIS   A HB3  1 
ATOM   1240 H HD1  . HIS   A 1 84  ? 22.638 45.178 22.26  0   30     ? 477  HIS   A HD1  1 
ATOM   1241 H HD2  . HIS   A 1 84  ? 21.293 41.615 23.226 1   12.776 ? 477  HIS   A HD2  1 
ATOM   1242 H HE1  . HIS   A 1 84  ? 24.494 43.94  23.122 1   12.194 ? 477  HIS   A HE1  1 
ATOM   1243 H HE2  . HIS   A 1 84  ? 23.678 41.806 23.706 0   30     ? 477  HIS   A HE2  1 
ATOM   1244 N N    . LEU   A 1 85  ? 18.375 43.015 24.461 1   11.412 ? 478  LEU   A N    1 
ATOM   1245 C CA   . LEU   A 1 85  ? 18.197 42.084 25.556 1   12.238 ? 478  LEU   A CA   1 
ATOM   1246 C C    . LEU   A 1 85  ? 19.165 40.92  25.387 1   12.07  ? 478  LEU   A C    1 
ATOM   1247 O O    . LEU   A 1 85  ? 19.358 40.433 24.272 1   11.028 ? 478  LEU   A O    1 
ATOM   1248 C CB   . LEU   A 1 85  ? 16.737 41.642 25.565 1   13.963 ? 478  LEU   A CB   1 
ATOM   1249 C CG   . LEU   A 1 85  ? 15.712 42.768 25.724 1   15.64  ? 478  LEU   A CG   1 
ATOM   1250 C CD1  . LEU   A 1 85  ? 14.304 42.357 25.343 1   18.192 ? 478  LEU   A CD1  1 
ATOM   1251 C CD2  . LEU   A 1 85  ? 15.724 43.207 27.146 1   16.499 ? 478  LEU   A CD2  1 
ATOM   1252 H H    . LEU   A 1 85  ? 17.891 42.878 23.698 1   11.946 ? 478  LEU   A H    1 
ATOM   1253 H HA   . LEU   A 1 85  ? 18.401 42.553 26.402 1   12.345 ? 478  LEU   A HA   1 
ATOM   1254 H HB2  . LEU   A 1 85  ? 16.554 41.169 24.721 1   13.928 ? 478  LEU   A HB2  1 
ATOM   1255 H HB3  . LEU   A 1 85  ? 16.614 40.999 26.301 1   13.933 ? 478  LEU   A HB3  1 
ATOM   1256 H HG   . LEU   A 1 85  ? 15.986 43.532 25.153 1   15.886 ? 478  LEU   A HG   1 
ATOM   1257 H HD11 . LEU   A 1 85  ? 14.303 42.002 24.438 1   17.386 ? 478  LEU   A HD11 1 
ATOM   1258 H HD12 . LEU   A 1 85  ? 13.717 43.131 25.387 1   17.357 ? 478  LEU   A HD12 1 
ATOM   1259 H HD13 . LEU   A 1 85  ? 13.987 41.675 25.958 1   17.386 ? 478  LEU   A HD13 1 
ATOM   1260 H HD21 . LEU   A 1 85  ? 16.593 43.584 27.365 1   16.176 ? 478  LEU   A HD21 1 
ATOM   1261 H HD22 . LEU   A 1 85  ? 15.547 42.446 27.724 1   16.193 ? 478  LEU   A HD22 1 
ATOM   1262 H HD23 . LEU   A 1 85  ? 15.037 43.882 27.283 1   16.226 ? 478  LEU   A HD23 1 
ATOM   1263 N N    . VAL   A 1 86  ? 19.771 40.522 26.503 1   10.863 ? 479  VAL   A N    1 
ATOM   1264 C CA   . VAL   A 1 86  ? 20.767 39.465 26.544 1   11.307 ? 479  VAL   A CA   1 
ATOM   1265 C C    . VAL   A 1 86  ? 20.195 38.21  25.881 1   12.139 ? 479  VAL   A C    1 
ATOM   1266 O O    . VAL   A 1 86  ? 19.092 37.782 26.2   1   12.068 ? 479  VAL   A O    1 
ATOM   1267 C CB   . VAL   A 1 86  ? 21.226 39.203 27.99  1   10.357 ? 479  VAL   A CB   1 
ATOM   1268 C CG1  . VAL   A 1 86  ? 20.095 38.784 28.941 1   10.226 ? 479  VAL   A CG1  1 
ATOM   1269 C CG2  . VAL   A 1 86  ? 22.343 38.166 28.049 1   10.857 ? 479  VAL   A CG2  1 
ATOM   1270 H H    . VAL   A 1 86  ? 19.558 40.943 27.286 1   11.236 ? 479  VAL   A H    1 
ATOM   1271 H HA   . VAL   A 1 86  ? 21.542 39.76  26.027 1   11.209 ? 479  VAL   A HA   1 
ATOM   1272 H HB   . VAL   A 1 86  ? 21.593 40.051 28.328 1   10.605 ? 479  VAL   A HB   1 
ATOM   1273 H HG11 . VAL   A 1 86  ? 19.842 37.864 28.759 1   10.307 ? 479  VAL   A HG11 1 
ATOM   1274 H HG12 . VAL   A 1 86  ? 19.325 39.362 28.81  1   10.284 ? 479  VAL   A HG12 1 
ATOM   1275 H HG13 . VAL   A 1 86  ? 20.401 38.859 29.86  1   10.276 ? 479  VAL   A HG13 1 
ATOM   1276 H HG21 . VAL   A 1 86  ? 22.579 37.997 28.976 1   10.737 ? 479  VAL   A HG21 1 
ATOM   1277 H HG22 . VAL   A 1 86  ? 23.122 38.499 27.573 1   10.718 ? 479  VAL   A HG22 1 
ATOM   1278 H HG23 . VAL   A 1 86  ? 22.043 37.338 27.638 1   10.734 ? 479  VAL   A HG23 1 
ATOM   1279 N N    . ALA   A 1 87  ? 20.955 37.632 24.934 1   13.236 ? 480  ALA   A N    1 
ATOM   1280 C CA   . ALA   A 1 87  ? 20.421 36.597 24.049 1   14.424 ? 480  ALA   A CA   1 
ATOM   1281 C C    . ALA   A 1 87  ? 19.977 35.364 24.84  1   14.091 ? 480  ALA   A C    1 
ATOM   1282 O O    . ALA   A 1 87  ? 18.924 34.789 24.568 1   15.789 ? 480  ALA   A O    1 
ATOM   1283 C CB   . ALA   A 1 87  ? 21.439 36.239 22.965 1   15.521 ? 480  ALA   A CB   1 
ATOM   1284 H H    . ALA   A 1 87  ? 21.828 37.886 24.839 1   13.199 ? 480  ALA   A H    1 
ATOM   1285 H HA   . ALA   A 1 87  ? 19.612 36.974 23.604 1   14.313 ? 480  ALA   A HA   1 
ATOM   1286 H HB1  . ALA   A 1 87  ? 21.75  37.049 22.528 1   15.261 ? 480  ALA   A HB1  1 
ATOM   1287 H HB2  . ALA   A 1 87  ? 22.196 35.78  23.366 1   15.288 ? 480  ALA   A HB2  1 
ATOM   1288 H HB3  . ALA   A 1 87  ? 21.024 35.658 22.306 1   15.223 ? 480  ALA   A HB3  1 
ATOM   1289 N N    . ASP   A 1 88  ? 20.75  34.959 25.846 1   13.955 ? 481  ASP   A N    1 
ATOM   1290 C CA   . ASP   A 1 88  ? 20.435 33.733 26.569 1   14.465 ? 481  ASP   A CA   1 
ATOM   1291 C C    . ASP   A 1 88  ? 19.54  33.97  27.793 1   13.78  ? 481  ASP   A C    1 
ATOM   1292 O O    . ASP   A 1 88  ? 19.299 33.024 28.506 1   12.745 ? 481  ASP   A O    1 
ATOM   1293 C CB   . ASP   A 1 88  ? 21.69  32.995 26.991 1   14.291 ? 481  ASP   A CB   1 
ATOM   1294 C CG   . ASP   A 1 88  ? 22.541 33.723 28.023 1   15.296 ? 481  ASP   A CG   1 
ATOM   1295 O OD1  . ASP   A 1 88  ? 22.125 34.843 28.479 1   13.564 ? 481  ASP   A OD1  1 
ATOM   1296 O OD2  . ASP   A 1 88  ? 23.572 33.141 28.374 1   14.625 ? 481  ASP   A OD2  1 
ATOM   1297 H H    . ASP   A 1 88  ? 21.486 35.445 26.087 1   14.103 ? 481  ASP   A H    1 
ATOM   1298 H HA   . ASP   A 1 88  ? 19.957 33.131 25.955 1   14.215 ? 481  ASP   A HA   1 
ATOM   1299 H HB2  . ASP   A 1 88  ? 21.44  32.121 27.358 1   14.545 ? 481  ASP   A HB2  1 
ATOM   1300 H HB3  . ASP   A 1 88  ? 22.242 32.839 26.197 1   14.553 ? 481  ASP   A HB3  1 
ATOM   1301 N N    . GLY   A 1 89  ? 19.128 35.221 28.073 1   14.41  ? 482  GLY   A N    1 
ATOM   1302 C CA   . GLY   A 1 89  ? 18.168 35.52  29.133 1   13.656 ? 482  GLY   A CA   1 
ATOM   1303 C C    . GLY   A 1 89  ? 18.778 35.637 30.539 1   13.094 ? 482  GLY   A C    1 
ATOM   1304 O O    . GLY   A 1 89  ? 18.038 35.807 31.521 1   12.792 ? 482  GLY   A O    1 
ATOM   1305 H H    . GLY   A 1 89  ? 19.463 35.917 27.585 1   14.041 ? 482  GLY   A H    1 
ATOM   1306 H HA2  . GLY   A 1 89  ? 17.715 36.368 28.912 1   13.703 ? 482  GLY   A HA2  1 
ATOM   1307 H HA3  . GLY   A 1 89  ? 17.481 34.813 29.141 1   13.699 ? 482  GLY   A HA3  1 
ATOM   1308 N N    . LYS   A 1 90  ? 20.11  35.576 30.653 1   12.476 ? 483  LYS   A N    1 
ATOM   1309 C CA   . LYS   A 1 90  ? 20.752 35.355 31.941 1   13.115 ? 483  LYS   A CA   1 
ATOM   1310 C C    . LYS   A 1 90  ? 21.603 36.547 32.374 1   12.446 ? 483  LYS   A C    1 
ATOM   1311 O O    . LYS   A 1 90  ? 22.052 37.316 31.556 1   12.708 ? 483  LYS   A O    1 
ATOM   1312 C CB   . LYS   A 1 90  ? 21.622 34.097 31.927 1   14.029 ? 483  LYS   A CB   1 
ATOM   1313 C CG   . LYS   A 1 90  ? 20.823 32.837 31.561 1   16.126 ? 483  LYS   A CG   1 
ATOM   1314 C CD   . LYS   A 1 90  ? 19.595 32.581 32.424 1   16.681 ? 483  LYS   A CD   1 
ATOM   1315 C CE   . LYS   A 1 90  ? 19.053 31.189 32.202 1   18.538 ? 483  LYS   A CE   1 
ATOM   1316 N NZ   . LYS   A 1 90  ? 18.463 31.05  30.877 1   19.034 ? 483  LYS   A NZ   1 
ATOM   1317 H H    . LYS   A 1 90  ? 20.634 35.683 29.912 1   12.785 ? 483  LYS   A H    1 
ATOM   1318 H HA   . LYS   A 1 90  ? 20.044 35.227 32.621 1   13.04  ? 483  LYS   A HA   1 
ATOM   1319 H HB2  . LYS   A 1 90  ? 22.347 34.212 31.276 1   14.258 ? 483  LYS   A HB2  1 
ATOM   1320 H HB3  . LYS   A 1 90  ? 22.025 33.972 32.812 1   14.249 ? 483  LYS   A HB3  1 
ATOM   1321 H HG2  . LYS   A 1 90  ? 20.541 32.911 30.625 1   15.744 ? 483  LYS   A HG2  1 
ATOM   1322 H HG3  . LYS   A 1 90  ? 21.421 32.065 31.627 1   15.845 ? 483  LYS   A HG3  1 
ATOM   1323 H HD2  . LYS   A 1 90  ? 19.834 32.688 33.37  1   16.94  ? 483  LYS   A HD2  1 
ATOM   1324 H HD3  . LYS   A 1 90  ? 18.898 33.237 32.204 1   16.901 ? 483  LYS   A HD3  1 
ATOM   1325 H HE2  . LYS   A 1 90  ? 19.772 30.539 32.3   1   18.198 ? 483  LYS   A HE2  1 
ATOM   1326 H HE3  . LYS   A 1 90  ? 18.375 30.995 32.873 1   18.211 ? 483  LYS   A HE3  1 
ATOM   1327 H HZ1  . LYS   A 1 90  ? 19.116 31.025 30.249 1   18.837 ? 483  LYS   A HZ1  1 
ATOM   1328 H HZ2  . LYS   A 1 90  ? 17.913 31.75  30.706 1   18.843 ? 483  LYS   A HZ2  1 
ATOM   1329 H HZ3  . LYS   A 1 90  ? 17.985 30.282 30.836 1   18.865 ? 483  LYS   A HZ3  1 
ATOM   1330 N N    . PHE   A 1 91  ? 21.819 36.67  33.69  1   13.258 ? 484  PHE   A N    1 
ATOM   1331 C CA   . PHE   A 1 91  ? 22.703 37.678 34.277 1   12.278 ? 484  PHE   A CA   1 
ATOM   1332 C C    . PHE   A 1 91  ? 24.161 37.383 33.932 1   13.291 ? 484  PHE   A C    1 
ATOM   1333 O O    . PHE   A 1 91  ? 24.868 38.236 33.391 1   13.961 ? 484  PHE   A O    1 
ATOM   1334 C CB   . PHE   A 1 91  ? 22.456 37.788 35.783 1   11.512 ? 484  PHE   A CB   1 
ATOM   1335 C CG   . PHE   A 1 91  ? 21.194 38.588 36.088 1   11.514 ? 484  PHE   A CG   1 
ATOM   1336 C CD1  . PHE   A 1 91  ? 19.956 37.971 36.14  1   11.62  ? 484  PHE   A CD1  1 
ATOM   1337 C CD2  . PHE   A 1 91  ? 21.258 39.966 36.251 1   12.038 ? 484  PHE   A CD2  1 
ATOM   1338 C CE1  . PHE   A 1 91  ? 18.806 38.703 36.385 1   12.001 ? 484  PHE   A CE1  1 
ATOM   1339 C CE2  . PHE   A 1 91  ? 20.108 40.7   36.482 1   11.899 ? 484  PHE   A CE2  1 
ATOM   1340 C CZ   . PHE   A 1 91  ? 18.891 40.076 36.546 1   12.366 ? 484  PHE   A CZ   1 
ATOM   1341 H H    . PHE   A 1 91  ? 21.391 36.093 34.255 1   12.82  ? 484  PHE   A H    1 
ATOM   1342 H HA   . PHE   A 1 91  ? 22.47  38.554 33.87  1   12.495 ? 484  PHE   A HA   1 
ATOM   1343 H HB2  . PHE   A 1 91  ? 22.368 36.884 36.16  1   11.691 ? 484  PHE   A HB2  1 
ATOM   1344 H HB3  . PHE   A 1 91  ? 23.229 38.229 36.202 1   11.692 ? 484  PHE   A HB3  1 
ATOM   1345 H HD1  . PHE   A 1 91  ? 19.897 37.037 36.023 1   11.676 ? 484  PHE   A HD1  1 
ATOM   1346 H HD2  . PHE   A 1 91  ? 22.092 40.404 36.196 1   11.883 ? 484  PHE   A HD2  1 
ATOM   1347 H HE1  . PHE   A 1 91  ? 17.968 38.27  36.431 1   11.99  ? 484  PHE   A HE1  1 
ATOM   1348 H HE2  . PHE   A 1 91  ? 20.164 41.633 36.602 1   12.016 ? 484  PHE   A HE2  1 
ATOM   1349 H HZ   . PHE   A 1 91  ? 18.112 40.579 36.721 1   12.16  ? 484  PHE   A HZ   1 
ATOM   1350 N N    . GLY   A 1 92  ? 24.625 36.2   34.318 1   14.995 ? 485  GLY   A N    1 
ATOM   1351 C CA   . GLY   A 1 92  ? 25.95  35.727 33.952 1   15.175 ? 485  GLY   A CA   1 
ATOM   1352 C C    . GLY   A 1 92  ? 26.631 34.998 35.111 1   15.655 ? 485  GLY   A C    1 
ATOM   1353 O O    . GLY   A 1 92  ? 26.779 35.55  36.187 1   15.912 ? 485  GLY   A O    1 
ATOM   1354 H H    . GLY   A 1 92  ? 24.095 35.66  34.832 1   14.572 ? 485  GLY   A H    1 
ATOM   1355 H HA2  . GLY   A 1 92  ? 25.871 35.122 33.18  1   15.246 ? 485  GLY   A HA2  1 
ATOM   1356 H HA3  . GLY   A 1 92  ? 26.506 36.494 33.679 1   15.22  ? 485  GLY   A HA3  1 
ATOM   1357 N N    . THR   A 1 93  ? 27.015 33.737 34.871 1   15.922 ? 486  THR   A N    1 
ATOM   1358 C CA   . THR   A 1 93  ? 27.933 32.974 35.689 1   17.095 ? 486  THR   A CA   1 
ATOM   1359 C C    . THR   A 1 93  ? 29.025 32.438 34.767 1   19.088 ? 486  THR   A C    1 
ATOM   1360 O O    . THR   A 1 93  ? 28.874 32.471 33.56  1   17.688 ? 486  THR   A O    1 
ATOM   1361 C CB   . THR   A 1 93  ? 27.248 31.814 36.41  1   18.466 ? 486  THR   A CB   1 
ATOM   1362 O OG1  . THR   A 1 93  ? 26.68  30.924 35.452 1   19.922 ? 486  THR   A OG1  1 
ATOM   1363 C CG2  . THR   A 1 93  ? 26.191 32.293 37.383 1   17.857 ? 486  THR   A CG2  1 
ATOM   1364 H H    . THR   A 1 93  ? 26.665 33.323 34.135 1   16.136 ? 486  THR   A H    1 
ATOM   1365 H HA   . THR   A 1 93  ? 28.339 33.57  36.355 1   17.451 ? 486  THR   A HA   1 
ATOM   1366 H HB   . THR   A 1 93  ? 27.931 31.324 36.927 1   18.364 ? 486  THR   A HB   1 
ATOM   1367 H HG1  . THR   A 1 93  ? 26.091 31.356 34.975 0   30     ? 486  THR   A HG1  1 
ATOM   1368 H HG21 . THR   A 1 93  ? 25.723 31.528 37.758 1   18.013 ? 486  THR   A HG21 1 
ATOM   1369 H HG22 . THR   A 1 93  ? 25.558 32.865 36.919 1   18.003 ? 486  THR   A HG22 1 
ATOM   1370 H HG23 . THR   A 1 93  ? 26.614 32.796 38.1   1   18.03  ? 486  THR   A HG23 1 
ATOM   1371 N N    . GLN   A 1 94  ? 30.125 31.986 35.366 1   21.732 ? 487  GLN   A N    1 
ATOM   1372 C CA   . GLN   A 1 94  ? 31.261 31.431 34.642 1   24.699 ? 487  GLN   A CA   1 
ATOM   1373 C C    . GLN   A 1 94  ? 31.091 29.92  34.574 1   26.415 ? 487  GLN   A C    1 
ATOM   1374 O O    . GLN   A 1 94  ? 30.99  29.313 35.628 1   33.779 ? 487  GLN   A O    1 
ATOM   1375 C CB   . GLN   A 1 94  ? 32.54  31.884 35.357 1   24.738 ? 487  GLN   A CB   1 
ATOM   1376 C CG   . GLN   A 1 94  ? 33.765 31.865 34.456 1   27.537 ? 487  GLN   A CG   1 
ATOM   1377 C CD   . GLN   A 1 94  ? 35.079 32.104 35.165 1   25.64  ? 487  GLN   A CD   1 
ATOM   1378 O OE1  . GLN   A 1 94  ? 35.202 31.948 36.374 1   32.642 ? 487  GLN   A OE1  1 
ATOM   1379 N NE2  . GLN   A 1 94  ? 36.088 32.476 34.402 1   26.377 ? 487  GLN   A NE2  1 
ATOM   1380 H H    . GLN   A 1 94  ? 30.17  32.023 36.278 1   21.637 ? 487  GLN   A H    1 
ATOM   1381 H HA   . GLN   A 1 94  ? 31.261 31.8   33.726 1   24.182 ? 487  GLN   A HA   1 
ATOM   1382 H HB2  . GLN   A 1 94  ? 32.408 32.793 35.697 1   25.277 ? 487  GLN   A HB2  1 
ATOM   1383 H HB3  . GLN   A 1 94  ? 32.698 31.297 36.125 1   25.405 ? 487  GLN   A HB3  1 
ATOM   1384 H HG2  . GLN   A 1 94  ? 33.813 30.997 34.003 1   26.409 ? 487  GLN   A HG2  1 
ATOM   1385 H HG3  . GLN   A 1 94  ? 33.661 32.551 33.762 1   26.429 ? 487  GLN   A HG3  1 
ATOM   1386 H HE21 . GLN   A 1 94  ? 36.889 32.115 34.522 1   26.149 ? 487  GLN   A HE21 1 
ATOM   1387 H HE22 . GLN   A 1 94  ? 35.964 33.086 33.77  1   26.15  ? 487  GLN   A HE22 1 
ATOM   1388 N N    . GLU   A 1 95  ? 31.023 29.364 33.349 1   24.852 ? 488  GLU   A N    1 
ATOM   1389 C CA   . GLU   A 1 95  ? 30.711 27.972 33.043 1   26.998 ? 488  GLU   A CA   1 
ATOM   1390 C C    . GLU   A 1 95  ? 31.821 27.356 32.175 1   28.727 ? 488  GLU   A C    1 
ATOM   1391 O O    . GLU   A 1 95  ? 32.434 28.019 31.335 1   25.662 ? 488  GLU   A O    1 
ATOM   1392 C CB   . GLU   A 1 95  ? 29.416 27.846 32.241 1   28.671 ? 488  GLU   A CB   1 
ATOM   1393 C CG   . GLU   A 1 95  ? 29.549 28.33  30.793 1   32.543 ? 488  GLU   A CG   1 
ATOM   1394 C CD   . GLU   A 1 95  ? 28.299 28.632 29.98  1   37.467 ? 488  GLU   A CD   1 
ATOM   1395 O OE1  . GLU   A 1 95  ? 27.177 28.553 30.537 1   30.853 ? 488  GLU   A OE1  1 
ATOM   1396 O OE2  . GLU   A 1 95  ? 28.467 28.959 28.767 1   38.428 ? 488  GLU   A OE2  1 
ATOM   1397 H H    . GLU   A 1 95  ? 31.196 29.913 32.639 1   25.724 ? 488  GLU   A H    1 
ATOM   1398 H HA   . GLU   A 1 95  ? 30.636 27.465 33.891 1   27.208 ? 488  GLU   A HA   1 
ATOM   1399 H HB2  . GLU   A 1 95  ? 29.136 26.907 32.238 1   29.107 ? 488  GLU   A HB2  1 
ATOM   1400 H HB3  . GLU   A 1 95  ? 28.716 28.365 32.689 1   29.114 ? 488  GLU   A HB3  1 
ATOM   1401 H HG2  . GLU   A 1 95  ? 30.097 29.143 30.795 1   32.358 ? 488  GLU   A HG2  1 
ATOM   1402 H HG3  . GLU   A 1 95  ? 30.06  27.658 30.295 1   32.548 ? 488  GLU   A HG3  1 
ATOM   1403 N N    . ARG   A 1 96  ? 32.057 26.052 32.351 1   31.493 ? 489  ARG   A N    1 
ATOM   1404 C CA   . ARG   A 1 96  ? 32.992 25.332 31.502 1   28.816 ? 489  ARG   A CA   1 
ATOM   1405 C C    . ARG   A 1 96  ? 32.345 25.245 30.14  1   27.305 ? 489  ARG   A C    1 
ATOM   1406 O O    . ARG   A 1 96  ? 31.154 24.998 30.064 1   34.267 ? 489  ARG   A O    1 
ATOM   1407 C CB   . ARG   A 1 96  ? 33.33  23.954 32.084 1   33.665 ? 489  ARG   A CB   1 
ATOM   1408 C CG   . ARG   A 1 96  ? 34.317 24.029 33.242 1   34.868 ? 489  ARG   A CG   1 
ATOM   1409 C CD   . ARG   A 1 96  ? 34.819 22.65  33.664 1   37.265 ? 489  ARG   A CD   1 
ATOM   1410 N NE   . ARG   A 1 96  ? 33.729 21.693 33.905 1   42.602 ? 489  ARG   A NE   1 
ATOM   1411 C CZ   . ARG   A 1 96  ? 33.216 20.797 33.045 1   42.263 ? 489  ARG   A CZ   1 
ATOM   1412 N NH1  . ARG   A 1 96  ? 33.466 20.842 31.729 1   33.488 ? 489  ARG   A NH1  1 
ATOM   1413 N NH2  . ARG   A 1 96  ? 32.394 19.876 33.526 1   43.931 ? 489  ARG   A NH2  1 
ATOM   1414 H H    . ARG   A 1 96  ? 31.625 25.6   33.016 1   30.193 ? 489  ARG   A H    1 
ATOM   1415 H HA   . ARG   A 1 96  ? 33.823 25.864 31.432 1   29.623 ? 489  ARG   A HA   1 
ATOM   1416 H HB2  . ARG   A 1 96  ? 32.503 23.526 32.394 1   32.792 ? 489  ARG   A HB2  1 
ATOM   1417 H HB3  . ARG   A 1 96  ? 33.71  23.394 31.375 1   32.606 ? 489  ARG   A HB3  1 
ATOM   1418 H HG2  . ARG   A 1 96  ? 35.084 24.582 32.978 1   35.078 ? 489  ARG   A HG2  1 
ATOM   1419 H HG3  . ARG   A 1 96  ? 33.882 24.46  34.01  1   35.11  ? 489  ARG   A HG3  1 
ATOM   1420 H HD2  . ARG   A 1 96  ? 35.409 22.296 32.969 1   37.669 ? 489  ARG   A HD2  1 
ATOM   1421 H HD3  . ARG   A 1 96  ? 35.348 22.744 34.483 1   37.848 ? 489  ARG   A HD3  1 
ATOM   1422 H HE   . ARG   A 1 96  ? 33.369 21.707 34.698 1   41.254 ? 489  ARG   A HE   1 
ATOM   1423 H HH11 . ARG   A 1 96  ? 34.296 20.758 31.437 1   35.931 ? 489  ARG   A HH11 1 
ATOM   1424 H HH12 . ARG   A 1 96  ? 32.8   20.956 31.159 1   35.768 ? 489  ARG   A HH12 1 
ATOM   1425 H HH21 . ARG   A 1 96  ? 32.509 19.566 34.346 1   43.387 ? 489  ARG   A HH21 1 
ATOM   1426 H HH22 . ARG   A 1 96  ? 31.734 19.572 33.022 1   43.405 ? 489  ARG   A HH22 1 
ATOM   1427 N N    . VAL   A 1 97  ? 33.112 25.52  29.081 1   26.117 ? 490  VAL   A N    1 
ATOM   1428 C CA   . VAL   A 1 97  ? 32.571 25.56  27.74  1   26.011 ? 490  VAL   A CA   1 
ATOM   1429 C C    . VAL   A 1 97  ? 32.901 24.262 27.012 1   25.629 ? 490  VAL   A C    1 
ATOM   1430 O O    . VAL   A 1 97  ? 34.045 23.779 27.015 1   21.755 ? 490  VAL   A O    1 
ATOM   1431 C CB   . VAL   A 1 97  ? 33.074 26.738 26.893 1   27.414 ? 490  VAL   A CB   1 
ATOM   1432 C CG1  . VAL   A 1 97  ? 32.765 28.058 27.574 1   30.375 ? 490  VAL   A CG1  1 
ATOM   1433 C CG2  . VAL   A 1 97  ? 34.556 26.649 26.557 1   26.703 ? 490  VAL   A CG2  1 
ATOM   1434 H H    . VAL   A 1 97  ? 34.003 25.685 29.203 1   26.417 ? 490  VAL   A H    1 
ATOM   1435 H HA   . VAL   A 1 97  ? 31.6   25.634 27.808 1   26.204 ? 490  VAL   A HA   1 
ATOM   1436 H HB   . VAL   A 1 97  ? 32.574 26.717 26.043 1   27.54  ? 490  VAL   A HB   1 
ATOM   1437 H HG11 . VAL   A 1 97  ? 33.463 28.264 28.218 1   29.474 ? 490  VAL   A HG11 1 
ATOM   1438 H HG12 . VAL   A 1 97  ? 31.91  27.997 28.031 1   29.527 ? 490  VAL   A HG12 1 
ATOM   1439 H HG13 . VAL   A 1 97  ? 32.725 28.76  26.906 1   29.525 ? 490  VAL   A HG13 1 
ATOM   1440 H HG21 . VAL   A 1 97  ? 34.906 27.541 26.392 1   26.893 ? 490  VAL   A HG21 1 
ATOM   1441 H HG22 . VAL   A 1 97  ? 34.677 26.104 25.762 1   26.85  ? 490  VAL   A HG22 1 
ATOM   1442 H HG23 . VAL   A 1 97  ? 35.036 26.248 27.3   1   26.783 ? 490  VAL   A HG23 1 
ATOM   1443 N N    . ASN   A 1 98  ? 31.888 23.741 26.317 1   20.444 ? 491  ASN   A N    1 
ATOM   1444 C CA   . ASN   A 1 98  ? 32.175 22.757 25.315 1   19.892 ? 491  ASN   A CA   1 
ATOM   1445 C C    . ASN   A 1 98  ? 32.73  21.495 25.994 1   17.394 ? 491  ASN   A C    1 
ATOM   1446 O O    . ASN   A 1 98  ? 33.578 20.778 25.452 1   16.629 ? 491  ASN   A O    1 
ATOM   1447 C CB   . ASN   A 1 98  ? 33.095 23.462 24.348 1   22.91  ? 491  ASN   A CB   1 
ATOM   1448 C CG   . ASN   A 1 98  ? 33.032 22.849 22.991 1   23.579 ? 491  ASN   A CG   1 
ATOM   1449 O OD1  . ASN   A 1 98  ? 34.086 22.619 22.4   1   29.365 ? 491  ASN   A OD1  1 
ATOM   1450 N ND2  . ASN   A 1 98  ? 31.818 22.629 22.512 1   21.909 ? 491  ASN   A ND2  1 
ATOM   1451 H H    . ASN   A 1 98  ? 31.024 23.996 26.471 1   21.511 ? 491  ASN   A H    1 
ATOM   1452 H HA   . ASN   A 1 98  ? 31.34  22.535 24.848 1   20.087 ? 491  ASN   A HA   1 
ATOM   1453 H HB2  . ASN   A 1 98  ? 32.843 24.405 24.285 1   22.345 ? 491  ASN   A HB2  1 
ATOM   1454 H HB3  . ASN   A 1 98  ? 34.014 23.412 24.676 1   22.384 ? 491  ASN   A HB3  1 
ATOM   1455 H HD21 . ASN   A 1 98  ? 31.475 23.192 21.919 1   22.4   ? 491  ASN   A HD21 1 
ATOM   1456 H HD22 . ASN   A 1 98  ? 31.334 21.955 22.812 1   22.369 ? 491  ASN   A HD22 1 
ATOM   1457 N N    . ASN   A 1 99  ? 32.259 21.278 27.22  1   15.476 ? 492  ASN   A N    1 
ATOM   1458 C CA   . ASN   A 1 99  ? 32.622 20.145 28.048 1   18.329 ? 492  ASN   A CA   1 
ATOM   1459 C C    . ASN   A 1 99  ? 34.135 20.066 28.256 1   17.701 ? 492  ASN   A C    1 
ATOM   1460 O O    . ASN   A 1 99  ? 34.625 18.992 28.57  1   22.106 ? 492  ASN   A O    1 
ATOM   1461 C CB   . ASN   A 1 99  ? 31.995 18.872 27.489 1   19.254 ? 492  ASN   A CB   1 
ATOM   1462 C CG   . ASN   A 1 99  ? 30.491 18.898 27.652 1   24.349 ? 492  ASN   A CG   1 
ATOM   1463 O OD1  . ASN   A 1 99  ? 29.715 19.032 26.687 1   27.064 ? 492  ASN   A OD1  1 
ATOM   1464 N ND2  . ASN   A 1 99  ? 30.049 18.816 28.892 1   25.296 ? 492  ASN   A ND2  1 
ATOM   1465 H H    . ASN   A 1 99  ? 31.651 21.87  27.56  1   16.632 ? 492  ASN   A H    1 
ATOM   1466 H HA   . ASN   A 1 99  ? 32.219 20.294 28.933 1   17.931 ? 492  ASN   A HA   1 
ATOM   1467 H HB2  . ASN   A 1 99  ? 32.218 18.785 26.541 1   20.066 ? 492  ASN   A HB2  1 
ATOM   1468 H HB3  . ASN   A 1 99  ? 32.357 18.096 27.961 1   20.103 ? 492  ASN   A HB3  1 
ATOM   1469 H HD21 . ASN   A 1 99  ? 29.261 19.164 29.104 1   25.005 ? 492  ASN   A HD21 1 
ATOM   1470 H HD22 . ASN   A 1 99  ? 30.539 18.413 29.512 1   24.958 ? 492  ASN   A HD22 1 
ATOM   1471 N N    . SER   A 1 100 ? 34.845 21.2   28.163 1   15.111 ? 493  SER   A N    1 
ATOM   1472 C CA   . SER   A 1 100 ? 36.287 21.287 28.36  1   16.501 ? 493  SER   A CA   1 
ATOM   1473 C C    . SER   A 1 100 ? 36.598 21.849 29.746 1   18.273 ? 493  SER   A C    1 
ATOM   1474 O O    . SER   A 1 100 ? 35.684 22.159 30.505 1   16.836 ? 493  SER   A O    1 
ATOM   1475 C CB   . SER   A 1 100 ? 36.918 22.179 27.314 1   18.191 ? 493  SER   A CB   1 
ATOM   1476 O OG   . SER   A 1 100 ? 36.704 23.559 27.625 1   17.004 ? 493  SER   A OG   1 
ATOM   1477 H H    . SER   A 1 100 ? 34.397 21.975 27.985 1   16.065 ? 493  SER   A H    1 
ATOM   1478 H HA   . SER   A 1 100 ? 36.676 20.381 28.288 1   16.858 ? 493  SER   A HA   1 
ATOM   1479 H HB2  . SER   A 1 100 ? 37.876 22     27.272 1   17.527 ? 493  SER   A HB2  1 
ATOM   1480 H HB3  . SER   A 1 100 ? 36.53  21.978 26.442 1   17.514 ? 493  SER   A HB3  1 
ATOM   1481 H HG   . SER   A 1 100 ? 37.074 24.017 27.008 0   30     ? 493  SER   A HG   1 
ATOM   1482 N N    . ASN   A 1 101 ? 37.887 22.038 30.054 1   20.079 ? 494  ASN   A N    1 
ATOM   1483 C CA   . ASN   A 1 101 ? 38.263 22.765 31.255 1   22.644 ? 494  ASN   A CA   1 
ATOM   1484 C C    . ASN   A 1 101 ? 38.313 24.28  31.043 1   21.292 ? 494  ASN   A C    1 
ATOM   1485 O O    . ASN   A 1 101 ? 38.435 25.029 32.005 1   23.83  ? 494  ASN   A O    1 
ATOM   1486 C CB   . ASN   A 1 101 ? 39.588 22.246 31.798 1   26.233 ? 494  ASN   A CB   1 
ATOM   1487 C CG   . ASN   A 1 101 ? 39.373 20.935 32.498 1   28.421 ? 494  ASN   A CG   1 
ATOM   1488 O OD1  . ASN   A 1 101 ? 39.966 19.919 32.123 1   32.472 ? 494  ASN   A OD1  1 
ATOM   1489 N ND2  . ASN   A 1 101 ? 38.499 20.936 33.492 1   29.006 ? 494  ASN   A ND2  1 
ATOM   1490 H H    . ASN   A 1 101 ? 38.542 21.703 29.512 1   20.185 ? 494  ASN   A H    1 
ATOM   1491 H HA   . ASN   A 1 101 ? 37.58  22.588 31.939 1   22.515 ? 494  ASN   A HA   1 
ATOM   1492 H HB2  . ASN   A 1 101 ? 40.221 22.124 31.062 1   25.832 ? 494  ASN   A HB2  1 
ATOM   1493 H HB3  . ASN   A 1 101 ? 39.964 22.894 32.426 1   25.807 ? 494  ASN   A HB3  1 
ATOM   1494 H HD21 . ASN   A 1 101 ? 38.095 20.183 33.727 1   28.797 ? 494  ASN   A HD21 1 
ATOM   1495 H HD22 . ASN   A 1 101 ? 38.326 21.688 33.931 1   28.708 ? 494  ASN   A HD22 1 
ATOM   1496 N N    . LYS   A 1 102 ? 38.18  24.752 29.808 1   18.714 ? 495  LYS   A N    1 
ATOM   1497 C CA   . LYS   A 1 102 ? 38.148 26.177 29.545 1   18.251 ? 495  LYS   A CA   1 
ATOM   1498 C C    . LYS   A 1 102 ? 36.81  26.734 30.045 1   18.592 ? 495  LYS   A C    1 
ATOM   1499 O O    . LYS   A 1 102 ? 35.767 26.113 29.871 1   16.121 ? 495  LYS   A O    1 
ATOM   1500 C CB   . LYS   A 1 102 ? 38.35  26.423 28.049 1   18.972 ? 495  LYS   A CB   1 
ATOM   1501 H H    . LYS   A 1 102 ? 38.113 24.171 29.105 1   19.211 ? 495  LYS   A H    1 
ATOM   1502 H HA   . LYS   A 1 102 ? 38.887 26.608 30.046 1   18.567 ? 495  LYS   A HA   1 
ATOM   1503 H HB2  . LYS   A 1 102 ? 39.269 26.446 27.833 0   30     ? 495  LYS   A HB2  1 
ATOM   1504 H HB3  . LYS   A 1 102 ? 37.423 26.479 27.623 0   30     ? 495  LYS   A HB3  1 
ATOM   1505 N N    . LYS   A 1 103 ? 36.863 27.92  30.663 1   18.097 ? 496  LYS   A N    1 
ATOM   1506 C CA   . LYS   A 1 103 ? 35.683 28.558 31.227 1   18.674 ? 496  LYS   A CA   1 
ATOM   1507 C C    . LYS   A 1 103 ? 35.359 29.847 30.494 1   17.204 ? 496  LYS   A C    1 
ATOM   1508 O O    . LYS   A 1 103 ? 36.258 30.541 30.052 1   15.867 ? 496  LYS   A O    1 
ATOM   1509 C CB   . LYS   A 1 103 ? 35.881 28.872 32.705 1   23.592 ? 496  LYS   A CB   1 
ATOM   1510 C CG   . LYS   A 1 103 ? 35.776 27.66  33.575 1   26.715 ? 496  LYS   A CG   1 
ATOM   1511 C CD   . LYS   A 1 103 ? 36.271 27.977 34.975 1   32.566 ? 496  LYS   A CD   1 
ATOM   1512 C CE   . LYS   A 1 103 ? 36.234 26.769 35.86  1   35.838 ? 496  LYS   A CE   1 
ATOM   1513 N NZ   . LYS   A 1 103 ? 37.322 26.878 36.837 1   39.667 ? 496  LYS   A NZ   1 
ATOM   1514 H H    . LYS   A 1 103 ? 37.666 28.35  30.735 1   18.345 ? 496  LYS   A H    1 
ATOM   1515 H HA   . LYS   A 1 103 ? 34.919 27.938 31.136 1   19.139 ? 496  LYS   A HA   1 
ATOM   1516 H HB2  . LYS   A 1 103 ? 36.766 29.277 32.832 1   23.122 ? 496  LYS   A HB2  1 
ATOM   1517 H HB3  . LYS   A 1 103 ? 35.206 29.523 32.99  1   23.033 ? 496  LYS   A HB3  1 
ATOM   1518 H HG2  . LYS   A 1 103 ? 34.839 27.369 33.613 1   27.156 ? 496  LYS   A HG2  1 
ATOM   1519 H HG3  . LYS   A 1 103 ? 36.317 26.937 33.188 1   27.196 ? 496  LYS   A HG3  1 
ATOM   1520 H HD2  . LYS   A 1 103 ? 37.192 28.314 34.924 1   31.844 ? 496  LYS   A HD2  1 
ATOM   1521 H HD3  . LYS   A 1 103 ? 35.707 28.68  35.366 1   31.832 ? 496  LYS   A HD3  1 
ATOM   1522 H HE2  . LYS   A 1 103 ? 35.381 26.721 36.327 1   35.892 ? 496  LYS   A HE2  1 
ATOM   1523 H HE3  . LYS   A 1 103 ? 36.352 25.958 35.334 1   35.791 ? 496  LYS   A HE3  1 
ATOM   1524 H HZ1  . LYS   A 1 103 ? 37.297 27.69  37.239 1   38.396 ? 496  LYS   A HZ1  1 
ATOM   1525 H HZ2  . LYS   A 1 103 ? 38.12  26.775 36.421 1   38.387 ? 496  LYS   A HZ2  1 
ATOM   1526 H HZ3  . LYS   A 1 103 ? 37.231 26.233 37.466 1   38.426 ? 496  LYS   A HZ3  1 
ATOM   1527 N N    . GLU   A 1 104 ? 34.056 30.127 30.381 1   15.65  ? 497  GLU   A N    1 
ATOM   1528 C CA   . GLU   A 1 104 ? 33.549 31.355 29.82  1   16.605 ? 497  GLU   A CA   1 
ATOM   1529 C C    . GLU   A 1 104 ? 32.345 31.802 30.643 1   15.448 ? 497  GLU   A C    1 
ATOM   1530 O O    . GLU   A 1 104 ? 31.786 31.049 31.447 1   15.181 ? 497  GLU   A O    1 
ATOM   1531 C CB   . GLU   A 1 104 ? 33.167 31.284 28.344 1   20.672 ? 497  GLU   A CB   1 
ATOM   1532 C CG   . GLU   A 1 104 ? 34.382 31.199 27.422 1   25.442 ? 497  GLU   A CG   1 
ATOM   1533 C CD   . GLU   A 1 104 ? 34.013 31.002 25.954 1   30.76  ? 497  GLU   A CD   1 
ATOM   1534 O OE1  . GLU   A 1 104 ? 32.791 30.987 25.606 1   33.877 ? 497  GLU   A OE1  1 
ATOM   1535 O OE2  . GLU   A 1 104 ? 34.971 30.792 25.172 1   33.775 ? 497  GLU   A OE2  1 
ATOM   1536 H H    . GLU   A 1 104 ? 33.451 29.507 30.673 1   16.258 ? 497  GLU   A H    1 
ATOM   1537 H HA   . GLU   A 1 104 ? 34.254 32.046 29.912 1   16.88  ? 497  GLU   A HA   1 
ATOM   1538 H HB2  . GLU   A 1 104 ? 32.585 30.512 28.207 1   20.864 ? 497  GLU   A HB2  1 
ATOM   1539 H HB3  . GLU   A 1 104 ? 32.655 32.087 28.111 1   20.603 ? 497  GLU   A HB3  1 
ATOM   1540 H HG2  . GLU   A 1 104 ? 34.908 32.023 27.506 1   25.326 ? 497  GLU   A HG2  1 
ATOM   1541 H HG3  . GLU   A 1 104 ? 34.949 30.451 27.705 1   25.241 ? 497  GLU   A HG3  1 
ATOM   1542 N N    . TRP   A 1 105 ? 32.059 33.085 30.502 1   15.134 ? 498  TRP   A N    1 
ATOM   1543 C CA   . TRP   A 1 105 ? 30.905 33.693 31.132 1   14.724 ? 498  TRP   A CA   1 
ATOM   1544 C C    . TRP   A 1 105 ? 29.741 33.585 30.174 1   14.261 ? 498  TRP   A C    1 
ATOM   1545 O O    . TRP   A 1 105 ? 29.932 33.827 28.985 1   14.55  ? 498  TRP   A O    1 
ATOM   1546 C CB   . TRP   A 1 105 ? 31.212 35.155 31.475 1   15.694 ? 498  TRP   A CB   1 
ATOM   1547 C CG   . TRP   A 1 105 ? 32.104 35.278 32.668 1   15.684 ? 498  TRP   A CG   1 
ATOM   1548 C CD1  . TRP   A 1 105 ? 33.466 35.272 32.683 1   16.327 ? 498  TRP   A CD1  1 
ATOM   1549 C CD2  . TRP   A 1 105 ? 31.674 35.441 34.033 1   15.739 ? 498  TRP   A CD2  1 
ATOM   1550 N NE1  . TRP   A 1 105 ? 33.915 35.426 33.967 1   16.248 ? 498  TRP   A NE1  1 
ATOM   1551 C CE2  . TRP   A 1 105 ? 32.844 35.543 34.813 1   15.328 ? 498  TRP   A CE2  1 
ATOM   1552 C CE3  . TRP   A 1 105 ? 30.425 35.55  34.659 1   16.147 ? 498  TRP   A CE3  1 
ATOM   1553 C CZ2  . TRP   A 1 105 ? 32.801 35.709 36.184 1   14.442 ? 498  TRP   A CZ2  1 
ATOM   1554 C CZ3  . TRP   A 1 105 ? 30.385 35.715 36.026 1   16.529 ? 498  TRP   A CZ3  1 
ATOM   1555 C CH2  . TRP   A 1 105 ? 31.564 35.803 36.77  1   15.973 ? 498  TRP   A CH2  1 
ATOM   1556 H H    . TRP   A 1 105 ? 32.603 33.609 29.988 1   15.144 ? 498  TRP   A H    1 
ATOM   1557 H HA   . TRP   A 1 105 ? 30.693 33.202 31.969 1   14.954 ? 498  TRP   A HA   1 
ATOM   1558 H HB2  . TRP   A 1 105 ? 31.646 35.577 30.703 1   15.464 ? 498  TRP   A HB2  1 
ATOM   1559 H HB3  . TRP   A 1 105 ? 30.367 35.621 31.656 1   15.46  ? 498  TRP   A HB3  1 
ATOM   1560 H HD1  . TRP   A 1 105 ? 34.026 35.172 31.929 1   16.148 ? 498  TRP   A HD1  1 
ATOM   1561 H HE1  . TRP   A 1 105 ? 34.751 35.439 34.204 1   16.138 ? 498  TRP   A HE1  1 
ATOM   1562 H HE3  . TRP   A 1 105 ? 29.63  35.488 34.157 1   16.127 ? 498  TRP   A HE3  1 
ATOM   1563 H HZ2  . TRP   A 1 105 ? 33.591 35.771 36.693 1   15.019 ? 498  TRP   A HZ2  1 
ATOM   1564 H HZ3  . TRP   A 1 105 ? 29.553 35.78  36.463 1   16.286 ? 498  TRP   A HZ3  1 
ATOM   1565 H HH2  . TRP   A 1 105 ? 31.508 35.918 37.702 1   15.761 ? 498  TRP   A HH2  1 
ATOM   1566 N N    . ASN   A 1 106 ? 28.561 33.256 30.718 1   14.622 ? 499  ASN   A N    1 
ATOM   1567 C CA   . ASN   A 1 106 ? 27.31  33.336 29.985 1   14.623 ? 499  ASN   A CA   1 
ATOM   1568 C C    . ASN   A 1 106 ? 26.626 34.669 30.327 1   15.331 ? 499  ASN   A C    1 
ATOM   1569 O O    . ASN   A 1 106 ? 27.223 35.558 30.966 1   13.171 ? 499  ASN   A O    1 
ATOM   1570 C CB   . ASN   A 1 106 ? 26.468 32.086 30.263 1   16.853 ? 499  ASN   A CB   1 
ATOM   1571 C CG   . ASN   A 1 106 ? 26.207 31.847 31.733 1   19.051 ? 499  ASN   A CG   1 
ATOM   1572 O OD1  . ASN   A 1 106 ? 25.664 32.714 32.423 1   17.983 ? 499  ASN   A OD1  1 
ATOM   1573 N ND2  . ASN   A 1 106 ? 26.582 30.678 32.248 1   20.48  ? 499  ASN   A ND2  1 
ATOM   1574 H H    . ASN   A 1 106 ? 28.541 32.976 31.588 1   14.566 ? 499  ASN   A H    1 
ATOM   1575 H HA   . ASN   A 1 106 ? 27.517 33.338 29.023 1   15.134 ? 499  ASN   A HA   1 
ATOM   1576 H HB2  . ASN   A 1 106 ? 25.611 32.167 29.799 1   16.752 ? 499  ASN   A HB2  1 
ATOM   1577 H HB3  . ASN   A 1 106 ? 26.931 31.307 29.895 1   16.8   ? 499  ASN   A HB3  1 
ATOM   1578 H HD21 . ASN   A 1 106 ? 27.022 30.655 33.018 1   20.046 ? 499  ASN   A HD21 1 
ATOM   1579 H HD22 . ASN   A 1 106 ? 26.391 29.925 31.82  1   20.099 ? 499  ASN   A HD22 1 
ATOM   1580 N N    . GLY   A 1 107 ? 25.362 34.818 29.907 1   14.805 ? 500  GLY   A N    1 
ATOM   1581 C CA   . GLY   A 1 107 ? 24.563 35.988 30.25  1   13.314 ? 500  GLY   A CA   1 
ATOM   1582 C C    . GLY   A 1 107 ? 25.191 37.314 29.805 1   12.656 ? 500  GLY   A C    1 
ATOM   1583 O O    . GLY   A 1 107 ? 25.924 37.391 28.835 1   11.606 ? 500  GLY   A O    1 
ATOM   1584 H H    . GLY   A 1 107 ? 24.988 34.175 29.376 1   14.611 ? 500  GLY   A H    1 
ATOM   1585 H HA2  . GLY   A 1 107 ? 23.677 35.898 29.836 1   13.502 ? 500  GLY   A HA2  1 
ATOM   1586 H HA3  . GLY   A 1 107 ? 24.434 36.003 31.227 1   13.495 ? 500  GLY   A HA3  1 
ATOM   1587 N N    . MET   A 1 108 ? 24.816 38.383 30.496 1   12.158 ? 501  MET   A N    1 
ATOM   1588 C CA   . MET   A 1 108 ? 25.244 39.726 30.159 1   12.462 ? 501  MET   A CA   1 
ATOM   1589 C C    . MET   A 1 108 ? 26.743 39.857 30.381 1   12.869 ? 501  MET   A C    1 
ATOM   1590 O O    . MET   A 1 108 ? 27.371 40.609 29.658 1   13.267 ? 501  MET   A O    1 
ATOM   1591 C CB   . MET   A 1 108 ? 24.505 40.775 30.998 1   11.588 ? 501  MET   A CB   1 
ATOM   1592 C CG   . MET   A 1 108 ? 23.036 40.856 30.654 1   11.429 ? 501  MET   A CG   1 
ATOM   1593 S SD   . MET   A 1 108 ? 22.109 42.122 31.537 1   11.255 ? 501  MET   A SD   1 
ATOM   1594 C CE   . MET   A 1 108 ? 22.066 41.406 33.173 1   11.645 ? 501  MET   A CE   1 
ATOM   1595 H H    . MET   A 1 108 ? 24.259 38.272 31.213 1   12.359 ? 501  MET   A H    1 
ATOM   1596 H HA   . MET   A 1 108 ? 25.053 39.88  29.198 1   12.311 ? 501  MET   A HA   1 
ATOM   1597 H HB2  . MET   A 1 108 ? 24.604 40.549 31.947 1   11.742 ? 501  MET   A HB2  1 
ATOM   1598 H HB3  . MET   A 1 108 ? 24.92  41.652 30.85  1   11.745 ? 501  MET   A HB3  1 
ATOM   1599 H HG2  . MET   A 1 108 ? 22.949 41.028 29.697 1   11.427 ? 501  MET   A HG2  1 
ATOM   1600 H HG3  . MET   A 1 108 ? 22.621 39.989 30.835 1   11.436 ? 501  MET   A HG3  1 
ATOM   1601 H HE1  . MET   A 1 108 ? 21.645 42.033 33.79  1   11.548 ? 501  MET   A HE1  1 
ATOM   1602 H HE2  . MET   A 1 108 ? 21.552 40.578 33.151 1   11.553 ? 501  MET   A HE2  1 
ATOM   1603 H HE3  . MET   A 1 108 ? 22.975 41.219 33.47  1   11.549 ? 501  MET   A HE3  1 
ATOM   1604 N N    . MET   A 1 109 ? 27.285 39.132 31.378 1   13.161 ? 502  MET   A N    1 
ATOM   1605 C CA   . MET   A 1 109 ? 28.732 39.069 31.584 1   14.096 ? 502  MET   A CA   1 
ATOM   1606 C C    . MET   A 1 109 ? 29.435 38.613 30.291 1   14.194 ? 502  MET   A C    1 
ATOM   1607 O O    . MET   A 1 109 ? 30.378 39.262 29.834 1   12.272 ? 502  MET   A O    1 
ATOM   1608 C CB   . MET   A 1 109 ? 29.044 38.108 32.74  1   13.633 ? 502  MET   A CB   1 
ATOM   1609 C CG   . MET   A 1 109 ? 28.746 38.654 34.127 1   13.672 ? 502  MET   A CG   1 
ATOM   1610 S SD   . MET   A 1 109 ? 29.831 40.022 34.611 1   13.917 ? 502  MET   A SD   1 
ATOM   1611 C CE   . MET   A 1 109 ? 31.425 39.202 34.685 1   15.226 ? 502  MET   A CE   1 
ATOM   1612 H H    . MET   A 1 109 ? 26.739 38.675 31.951 1   13.285 ? 502  MET   A H    1 
ATOM   1613 H HA   . MET   A 1 109 ? 29.052 39.978 31.813 1   13.843 ? 502  MET   A HA   1 
ATOM   1614 H HB2  . MET   A 1 109 ? 28.524 37.286 32.607 1   13.743 ? 502  MET   A HB2  1 
ATOM   1615 H HB3  . MET   A 1 109 ? 29.993 37.866 32.693 1   13.761 ? 502  MET   A HB3  1 
ATOM   1616 H HG2  . MET   A 1 109 ? 27.819 38.965 34.157 1   13.711 ? 502  MET   A HG2  1 
ATOM   1617 H HG3  . MET   A 1 109 ? 28.84  37.934 34.782 1   13.719 ? 502  MET   A HG3  1 
ATOM   1618 H HE1  . MET   A 1 109 ? 32.062 39.771 35.155 1   14.884 ? 502  MET   A HE1  1 
ATOM   1619 H HE2  . MET   A 1 109 ? 31.332 38.356 35.161 1   14.885 ? 502  MET   A HE2  1 
ATOM   1620 H HE3  . MET   A 1 109 ? 31.746 39.033 33.78  1   14.879 ? 502  MET   A HE3  1 
ATOM   1621 N N    . GLY   A 1 110 ? 28.948 37.505 29.696 1   14.985 ? 503  GLY   A N    1 
ATOM   1622 C CA   . GLY   A 1 110 ? 29.541 36.941 28.485 1   15.105 ? 503  GLY   A CA   1 
ATOM   1623 C C    . GLY   A 1 110 ? 29.522 37.909 27.303 1   15.165 ? 503  GLY   A C    1 
ATOM   1624 O O    . GLY   A 1 110 ? 30.5   38.025 26.558 1   16.693 ? 503  GLY   A O    1 
ATOM   1625 H H    . GLY   A 1 110 ? 28.223 37.087 30.062 1   14.806 ? 503  GLY   A H    1 
ATOM   1626 H HA2  . GLY   A 1 110 ? 30.473 36.682 28.678 1   15.089 ? 503  GLY   A HA2  1 
ATOM   1627 H HA3  . GLY   A 1 110 ? 29.047 36.124 28.241 1   15.087 ? 503  GLY   A HA3  1 
ATOM   1628 N N    . GLU   A 1 111 ? 28.394 38.612 27.141 1   13.978 ? 504  GLU   A N    1 
ATOM   1629 C CA   . GLU   A 1 111 ? 28.203 39.535 26.03  1   13.27  ? 504  GLU   A CA   1 
ATOM   1630 C C    . GLU   A 1 111 ? 29.117 40.753 26.158 1   13.281 ? 504  GLU   A C    1 
ATOM   1631 O O    . GLU   A 1 111 ? 29.668 41.242 25.163 1   13.287 ? 504  GLU   A O    1 
ATOM   1632 C CB   . GLU   A 1 111 ? 26.742 39.948 25.952 1   13.625 ? 504  GLU   A CB   1 
ATOM   1633 C CG   . GLU   A 1 111 ? 25.818 38.825 25.488 1   13.501 ? 504  GLU   A CG   1 
ATOM   1634 C CD   . GLU   A 1 111 ? 24.587 39.333 24.759 1   14.546 ? 504  GLU   A CD   1 
ATOM   1635 O OE1  . GLU   A 1 111 ? 24.637 40.548 24.469 1   14.261 ? 504  GLU   A OE1  1 
ATOM   1636 O OE2  . GLU   A 1 111 ? 23.627 38.556 24.452 1   14.152 ? 504  GLU   A OE2  1 
ATOM   1637 H H    . GLU   A 1 111 ? 27.715 38.508 27.744 1   14.092 ? 504  GLU   A H    1 
ATOM   1638 H HA   . GLU   A 1 111 ? 28.437 39.059 25.192 1   13.497 ? 504  GLU   A HA   1 
ATOM   1639 H HB2  . GLU   A 1 111 ? 26.452 40.25  26.838 1   13.521 ? 504  GLU   A HB2  1 
ATOM   1640 H HB3  . GLU   A 1 111 ? 26.669 40.709 25.34  1   13.525 ? 504  GLU   A HB3  1 
ATOM   1641 H HG2  . GLU   A 1 111 ? 26.313 38.225 24.889 1   13.758 ? 504  GLU   A HG2  1 
ATOM   1642 H HG3  . GLU   A 1 111 ? 25.53  38.302 26.266 1   13.761 ? 504  GLU   A HG3  1 
ATOM   1643 N N    . LEU   A 1 112 ? 29.293 41.252 27.38  1   12.468 ? 505  LEU   A N    1 
ATOM   1644 C CA   . LEU   A 1 112 ? 30.237 42.34  27.634 1   12.586 ? 505  LEU   A CA   1 
ATOM   1645 C C    . LEU   A 1 112 ? 31.666 41.897 27.288 1   12.937 ? 505  LEU   A C    1 
ATOM   1646 O O    . LEU   A 1 112 ? 32.407 42.633 26.653 1   14.261 ? 505  LEU   A O    1 
ATOM   1647 C CB   . LEU   A 1 112 ? 30.15  42.758 29.104 1   11.866 ? 505  LEU   A CB   1 
ATOM   1648 C CG   . LEU   A 1 112 ? 31.052 43.932 29.521 1   12.196 ? 505  LEU   A CG   1 
ATOM   1649 C CD1  . LEU   A 1 112 ? 30.803 45.176 28.705 1   11.806 ? 505  LEU   A CD1  1 
ATOM   1650 C CD2  . LEU   A 1 112 ? 30.878 44.2   30.998 1   11.547 ? 505  LEU   A CD2  1 
ATOM   1651 H H    . LEU   A 1 112 ? 28.811 40.914 28.079 1   12.69  ? 505  LEU   A H    1 
ATOM   1652 H HA   . LEU   A 1 112 ? 29.991 43.108 27.059 1   12.498 ? 505  LEU   A HA   1 
ATOM   1653 H HB2  . LEU   A 1 112 ? 29.216 42.999 29.3   1   12.101 ? 505  LEU   A HB2  1 
ATOM   1654 H HB3  . LEU   A 1 112 ? 30.38  41.977 29.658 1   12.099 ? 505  LEU   A HB3  1 
ATOM   1655 H HG   . LEU   A 1 112 ? 31.995 43.661 29.375 1   11.942 ? 505  LEU   A HG   1 
ATOM   1656 H HD11 . LEU   A 1 112 ? 31.141 45.048 27.803 1   11.931 ? 505  LEU   A HD11 1 
ATOM   1657 H HD12 . LEU   A 1 112 ? 31.258 45.93  29.116 1   11.937 ? 505  LEU   A HD12 1 
ATOM   1658 H HD13 . LEU   A 1 112 ? 29.848 45.355 28.669 1   11.926 ? 505  LEU   A HD13 1 
ATOM   1659 H HD21 . LEU   A 1 112 ? 30.921 43.361 31.488 1   11.768 ? 505  LEU   A HD21 1 
ATOM   1660 H HD22 . LEU   A 1 112 ? 30.015 44.62  31.153 1   11.746 ? 505  LEU   A HD22 1 
ATOM   1661 H HD23 . LEU   A 1 112 ? 31.584 44.79  31.307 1   11.754 ? 505  LEU   A HD23 1 
ATOM   1662 N N    . LEU   A 1 113 ? 32.068 40.71  27.735 1   13.592 ? 506  LEU   A N    1 
ATOM   1663 C CA   . LEU   A 1 113 ? 33.438 40.258 27.506 1   15.478 ? 506  LEU   A CA   1 
ATOM   1664 C C    . LEU   A 1 113 ? 33.708 39.982 26.019 1   16.265 ? 506  LEU   A C    1 
ATOM   1665 O O    . LEU   A 1 113 ? 34.798 40.265 25.519 1   17.504 ? 506  LEU   A O    1 
ATOM   1666 C CB   . LEU   A 1 113 ? 33.706 39.046 28.391 1   13.931 ? 506  LEU   A CB   1 
ATOM   1667 C CG   . LEU   A 1 113 ? 33.859 39.359 29.881 1   14.006 ? 506  LEU   A CG   1 
ATOM   1668 C CD1  . LEU   A 1 113 ? 33.693 38.14  30.776 1   14.33  ? 506  LEU   A CD1  1 
ATOM   1669 C CD2  . LEU   A 1 113 ? 35.187 40.039 30.131 1   14.233 ? 506  LEU   A CD2  1 
ATOM   1670 H H    . LEU   A 1 113 ? 31.488 40.172 28.193 1   13.815 ? 506  LEU   A H    1 
ATOM   1671 H HA   . LEU   A 1 113 ? 34.044 40.99  27.786 1   14.914 ? 506  LEU   A HA   1 
ATOM   1672 H HB2  . LEU   A 1 113 ? 32.963 38.409 28.28  1   14.286 ? 506  LEU   A HB2  1 
ATOM   1673 H HB3  . LEU   A 1 113 ? 34.531 38.609 28.077 1   14.296 ? 506  LEU   A HB3  1 
ATOM   1674 H HG   . LEU   A 1 113 ? 33.147 40.004 30.127 1   14.092 ? 506  LEU   A HG   1 
ATOM   1675 H HD11 . LEU   A 1 113 ? 32.808 37.758 30.644 1   14.234 ? 506  LEU   A HD11 1 
ATOM   1676 H HD12 . LEU   A 1 113 ? 33.796 38.402 31.706 1   14.234 ? 506  LEU   A HD12 1 
ATOM   1677 H HD13 . LEU   A 1 113 ? 34.367 37.477 30.55  1   14.234 ? 506  LEU   A HD13 1 
ATOM   1678 H HD21 . LEU   A 1 113 ? 35.174 40.931 29.748 1   14.171 ? 506  LEU   A HD21 1 
ATOM   1679 H HD22 . LEU   A 1 113 ? 35.9   39.521 29.721 1   14.168 ? 506  LEU   A HD22 1 
ATOM   1680 H HD23 . LEU   A 1 113 ? 35.344 40.102 31.088 1   14.168 ? 506  LEU   A HD23 1 
ATOM   1681 N N    . SER   A 1 114 ? 32.705 39.487 25.298 1   16.765 ? 507  SER   A N    1 
ATOM   1682 C CA   . SER   A 1 114 ? 32.881 39.117 23.901 1   18.188 ? 507  SER   A CA   1 
ATOM   1683 C C    . SER   A 1 114 ? 32.821 40.335 22.986 1   18.346 ? 507  SER   A C    1 
ATOM   1684 O O    . SER   A 1 114 ? 33.177 40.25  21.812 1   17.807 ? 507  SER   A O    1 
ATOM   1685 C CB   . SER   A 1 114 ? 31.836 38.132 23.497 1   18.29  ? 507  SER   A CB   1 
ATOM   1686 O OG   . SER   A 1 114 ? 30.586 38.792 23.369 1   17.443 ? 507  SER   A OG   1 
ATOM   1687 H H    . SER   A 1 114 ? 31.885 39.371 25.685 1   16.924 ? 507  SER   A H    1 
ATOM   1688 H HA   . SER   A 1 114 ? 33.77  38.692 23.799 1   17.938 ? 507  SER   A HA   1 
ATOM   1689 H HB2  . SER   A 1 114 ? 32.082 37.725 22.645 1   18.062 ? 507  SER   A HB2  1 
ATOM   1690 H HB3  . SER   A 1 114 ? 31.77  37.429 24.171 1   18.062 ? 507  SER   A HB3  1 
ATOM   1691 H HG   . SER   A 1 114 ? 29.98  38.217 23.149 0   30     ? 507  SER   A HG   1 
ATOM   1692 N N    . GLY   A 1 115 ? 32.27  41.445 23.484 1   17.203 ? 508  GLY   A N    1 
ATOM   1693 C CA   . GLY   A 1 115 ? 32.123 42.638 22.675 1   16.681 ? 508  GLY   A CA   1 
ATOM   1694 C C    . GLY   A 1 115 ? 30.732 42.759 22.044 1   16.219 ? 508  GLY   A C    1 
ATOM   1695 O O    . GLY   A 1 115 ? 30.496 43.678 21.28  1   17.037 ? 508  GLY   A O    1 
ATOM   1696 H H    . GLY   A 1 115 ? 31.969 41.458 24.347 1   17.342 ? 508  GLY   A H    1 
ATOM   1697 H HA2  . GLY   A 1 115 ? 32.29  43.425 23.241 1   16.717 ? 508  GLY   A HA2  1 
ATOM   1698 H HA3  . GLY   A 1 115 ? 32.804 42.632 21.963 1   16.718 ? 508  GLY   A HA3  1 
ATOM   1699 N N    . GLN   A 1 116 ? 29.819 41.842 22.353 1   16.658 ? 509  GLN   A N    1 
ATOM   1700 C CA   . GLN   A 1 116 ? 28.442 41.937 21.908 1   17.968 ? 509  GLN   A CA   1 
ATOM   1701 C C    . GLN   A 1 116 ? 27.742 43.094 22.624 1   16.154 ? 509  GLN   A C    1 
ATOM   1702 O O    . GLN   A 1 116 ? 26.764 43.628 22.12  1   15.085 ? 509  GLN   A O    1 
ATOM   1703 C CB   . GLN   A 1 116 ? 27.712 40.624 22.201 1   21.718 ? 509  GLN   A CB   1 
ATOM   1704 C CG   . GLN   A 1 116 ? 28.156 39.438 21.347 1   24.053 ? 509  GLN   A CG   1 
ATOM   1705 C CD   . GLN   A 1 116 ? 27.718 38.121 21.959 1   30.349 ? 509  GLN   A CD   1 
ATOM   1706 O OE1  . GLN   A 1 116 ? 28.352 37.548 22.869 1   29.832 ? 509  GLN   A OE1  1 
ATOM   1707 N NE2  . GLN   A 1 116 ? 26.581 37.644 21.483 1   31.105 ? 509  GLN   A NE2  1 
ATOM   1708 H H    . GLN   A 1 116 ? 30.063 41.124 22.863 1   16.908 ? 509  GLN   A H    1 
ATOM   1709 H HA   . GLN   A 1 116 ? 28.434 42.107 20.932 1   17.959 ? 509  GLN   A HA   1 
ATOM   1710 H HB2  . GLN   A 1 116 ? 27.845 40.399 23.146 1   21.291 ? 509  GLN   A HB2  1 
ATOM   1711 H HB3  . GLN   A 1 116 ? 26.752 40.766 22.066 1   21.257 ? 509  GLN   A HB3  1 
ATOM   1712 H HG2  . GLN   A 1 116 ? 27.771 39.521 20.448 1   24.844 ? 509  GLN   A HG2  1 
ATOM   1713 H HG3  . GLN   A 1 116 ? 29.133 39.445 21.259 1   24.711 ? 509  GLN   A HG3  1 
ATOM   1714 H HE21 . GLN   A 1 116 ? 26.461 36.767 21.422 1   30.845 ? 509  GLN   A HE21 1 
ATOM   1715 H HE22 . GLN   A 1 116 ? 25.939 38.2   21.226 1   30.762 ? 509  GLN   A HE22 1 
ATOM   1716 N N    . ALA   A 1 117 ? 28.269 43.479 23.792 1   15.211 ? 510  ALA   A N    1 
ATOM   1717 C CA   . ALA   A 1 117 ? 27.845 44.69  24.468 1   14.167 ? 510  ALA   A CA   1 
ATOM   1718 C C    . ALA   A 1 117 ? 29.075 45.496 24.835 1   13.315 ? 510  ALA   A C    1 
ATOM   1719 O O    . ALA   A 1 117 ? 30.121 44.914 25.096 1   14.551 ? 510  ALA   A O    1 
ATOM   1720 C CB   . ALA   A 1 117 ? 27.064 44.319 25.711 1   15.18  ? 510  ALA   A CB   1 
ATOM   1721 H H    . ALA   A 1 117 ? 28.903 42.957 24.193 1   15.205 ? 510  ALA   A H    1 
ATOM   1722 H HA   . ALA   A 1 117 ? 27.274 45.229 23.853 1   14.387 ? 510  ALA   A HA   1 
ATOM   1723 H HB1  . ALA   A 1 117 ? 26.419 43.624 25.496 1   14.838 ? 510  ALA   A HB1  1 
ATOM   1724 H HB2  . ALA   A 1 117 ? 27.672 43.991 26.395 1   14.856 ? 510  ALA   A HB2  1 
ATOM   1725 H HB3  . ALA   A 1 117 ? 26.594 45.1   26.048 1   14.863 ? 510  ALA   A HB3  1 
ATOM   1726 N N    . ASP   A 1 118 ? 28.904 46.815 24.929 1   12.928 ? 511  ASP   A N    1 
ATOM   1727 C CA   . ASP   A 1 118 ? 29.91  47.704 25.483 1   14.638 ? 511  ASP   A CA   1 
ATOM   1728 C C    . ASP   A 1 118 ? 29.611 48.087 26.941 1   13.556 ? 511  ASP   A C    1 
ATOM   1729 O O    . ASP   A 1 118 ? 30.513 48.486 27.65  1   14.217 ? 511  ASP   A O    1 
ATOM   1730 C CB   . ASP   A 1 118 ? 30.016 48.952 24.624 1   15.601 ? 511  ASP   A CB   1 
ATOM   1731 C CG   . ASP   A 1 118 ? 30.355 48.64  23.172 1   16.904 ? 511  ASP   A CG   1 
ATOM   1732 O OD1  . ASP   A 1 118 ? 31.268 47.844 22.954 1   18.182 ? 511  ASP   A OD1  1 
ATOM   1733 O OD2  . ASP   A 1 118 ? 29.63  49.117 22.288 1   17.676 ? 511  ASP   A OD2  1 
ATOM   1734 H H    . ASP   A 1 118 ? 28.123 47.179 24.626 1   13.423 ? 511  ASP   A H    1 
ATOM   1735 H HA   . ASP   A 1 118 ? 30.78  47.247 25.454 1   14.273 ? 511  ASP   A HA   1 
ATOM   1736 H HB2  . ASP   A 1 118 ? 29.164 49.436 24.652 1   15.672 ? 511  ASP   A HB2  1 
ATOM   1737 H HB3  . ASP   A 1 118 ? 30.713 49.536 24.989 1   15.663 ? 511  ASP   A HB3  1 
ATOM   1738 N N    . MET   A 1 119 ? 28.348 48.014 27.372 1   13.066 ? 512  MET   A N    1 
ATOM   1739 C CA   . MET   A 1 119 ? 27.96  48.39  28.725 1   13.327 ? 512  MET   A CA   1 
ATOM   1740 C C    . MET   A 1 119 ? 26.766 47.52  29.125 1   12.508 ? 512  MET   A C    1 
ATOM   1741 O O    . MET   A 1 119 ? 25.851 47.286 28.315 1   12.356 ? 512  MET   A O    1 
ATOM   1742 C CB   . MET   A 1 119 ? 27.636 49.89  28.735 1   13.925 ? 512  MET   A CB   1 
ATOM   1743 C CG   . MET   A 1 119 ? 27.283 50.48  30.051 1   15.579 ? 512  MET   A CG   1 
ATOM   1744 S SD   . MET   A 1 119 ? 27.155 52.284 29.953 1   16.953 ? 512  MET   A SD   1 
ATOM   1745 C CE   . MET   A 1 119 ? 28.815 52.87  29.647 1   16.601 ? 512  MET   A CE   1 
ATOM   1746 H H    . MET   A 1 119 ? 27.698 47.723 26.799 1   13.243 ? 512  MET   A H    1 
ATOM   1747 H HA   . MET   A 1 119 ? 28.716 48.207 29.335 1   13.193 ? 512  MET   A HA   1 
ATOM   1748 H HB2  . MET   A 1 119 ? 28.413 50.371 28.378 1   14.192 ? 512  MET   A HB2  1 
ATOM   1749 H HB3  . MET   A 1 119 ? 26.89  50.044 28.117 1   14.158 ? 512  MET   A HB3  1 
ATOM   1750 H HG2  . MET   A 1 119 ? 26.429 50.116 30.356 1   15.347 ? 512  MET   A HG2  1 
ATOM   1751 H HG3  . MET   A 1 119 ? 27.967 50.245 30.71  1   15.389 ? 512  MET   A HG3  1 
ATOM   1752 H HE1  . MET   A 1 119 ? 28.832 53.843 29.704 1   16.684 ? 512  MET   A HE1  1 
ATOM   1753 H HE2  . MET   A 1 119 ? 29.42  52.495 30.314 1   16.684 ? 512  MET   A HE2  1 
ATOM   1754 H HE3  . MET   A 1 119 ? 29.099 52.592 28.757 1   16.669 ? 512  MET   A HE3  1 
ATOM   1755 N N    . ILE   A 1 120 ? 26.791 47.033 30.366 1   11.114 ? 513  ILE   A N    1 
ATOM   1756 C CA   . ILE   A 1 120 ? 25.646 46.378 30.973 1   10.681 ? 513  ILE   A CA   1 
ATOM   1757 C C    . ILE   A 1 120 ? 24.91  47.413 31.816 1   10.725 ? 513  ILE   A C    1 
ATOM   1758 O O    . ILE   A 1 120 ? 25.471 47.894 32.809 1   11.377 ? 513  ILE   A O    1 
ATOM   1759 C CB   . ILE   A 1 120 ? 26.047 45.183 31.847 1   11.158 ? 513  ILE   A CB   1 
ATOM   1760 C CG1  . ILE   A 1 120 ? 26.836 44.118 31.105 1   11.405 ? 513  ILE   A CG1  1 
ATOM   1761 C CG2  . ILE   A 1 120 ? 24.811 44.576 32.538 1   11.19  ? 513  ILE   A CG2  1 
ATOM   1762 C CD1  . ILE   A 1 120 ? 27.419 43.047 32.007 1   11.178 ? 513  ILE   A CD1  1 
ATOM   1763 H H    . ILE   A 1 120 ? 27.557 47.111 30.858 1   11.357 ? 513  ILE   A H    1 
ATOM   1764 H HA   . ILE   A 1 120 ? 25.052 46.061 30.267 1   10.862 ? 513  ILE   A HA   1 
ATOM   1765 H HB   . ILE   A 1 120 ? 26.63  45.529 32.552 1   11.121 ? 513  ILE   A HB   1 
ATOM   1766 H HG12 . ILE   A 1 120 ? 26.247 43.691 30.45  1   11.297 ? 513  ILE   A HG12 1 
ATOM   1767 H HG13 . ILE   A 1 120 ? 27.566 44.549 30.616 1   11.295 ? 513  ILE   A HG13 1 
ATOM   1768 H HG21 . ILE   A 1 120 ? 25.027 43.694 32.882 1   11.184 ? 513  ILE   A HG21 1 
ATOM   1769 H HG22 . ILE   A 1 120 ? 24.084 44.502 31.897 1   11.183 ? 513  ILE   A HG22 1 
ATOM   1770 H HG23 . ILE   A 1 120 ? 24.535 45.147 33.273 1   11.189 ? 513  ILE   A HG23 1 
ATOM   1771 H HD11 . ILE   A 1 120 ? 27.705 43.448 32.85  1   11.245 ? 513  ILE   A HD11 1 
ATOM   1772 H HD12 . ILE   A 1 120 ? 28.187 42.636 31.568 1   11.245 ? 513  ILE   A HD12 1 
ATOM   1773 H HD13 . ILE   A 1 120 ? 26.745 42.364 32.186 1   11.247 ? 513  ILE   A HD13 1 
ATOM   1774 N N    . VAL   A 1 121 ? 23.655 47.685 31.461 1   9.485  ? 514  VAL   A N    1 
ATOM   1775 C CA   . VAL   A 1 121 ? 22.813 48.595 32.228 1   10.285 ? 514  VAL   A CA   1 
ATOM   1776 C C    . VAL   A 1 121 ? 21.585 47.803 32.681 1   9.724  ? 514  VAL   A C    1 
ATOM   1777 O O    . VAL   A 1 121 ? 20.636 47.634 31.927 1   9.72   ? 514  VAL   A O    1 
ATOM   1778 C CB   . VAL   A 1 121 ? 22.417 49.867 31.472 1   10.167 ? 514  VAL   A CB   1 
ATOM   1779 C CG1  . VAL   A 1 121 ? 21.552 50.79  32.301 1   10.339 ? 514  VAL   A CG1  1 
ATOM   1780 C CG2  . VAL   A 1 121 ? 23.618 50.629 30.943 1   11.091 ? 514  VAL   A CG2  1 
ATOM   1781 H H    . VAL   A 1 121 ? 23.306 47.292 30.713 1   9.96   ? 514  VAL   A H    1 
ATOM   1782 H HA   . VAL   A 1 121 ? 23.308 48.866 33.024 1   10.01  ? 514  VAL   A HA   1 
ATOM   1783 H HB   . VAL   A 1 121 ? 21.884 49.584 30.692 1   10.386 ? 514  VAL   A HB   1 
ATOM   1784 H HG11 . VAL   A 1 121 ? 21.909 50.846 33.204 1   10.294 ? 514  VAL   A HG11 1 
ATOM   1785 H HG12 . VAL   A 1 121 ? 20.644 50.442 32.335 1   10.292 ? 514  VAL   A HG12 1 
ATOM   1786 H HG13 . VAL   A 1 121 ? 21.542 51.676 31.903 1   10.315 ? 514  VAL   A HG13 1 
ATOM   1787 H HG21 . VAL   A 1 121 ? 23.322 51.454 30.523 1   10.813 ? 514  VAL   A HG21 1 
ATOM   1788 H HG22 . VAL   A 1 121 ? 24.085 50.083 30.289 1   10.833 ? 514  VAL   A HG22 1 
ATOM   1789 H HG23 . VAL   A 1 121 ? 24.219 50.838 31.677 1   10.837 ? 514  VAL   A HG23 1 
ATOM   1790 N N    . ALA   A 1 122 ? 21.627 47.323 33.924 1   8.836  ? 515  ALA   A N    1 
ATOM   1791 C CA   . ALA   A 1 122 ? 20.708 46.298 34.405 1   9.139  ? 515  ALA   A CA   1 
ATOM   1792 C C    . ALA   A 1 122 ? 20.82  46.249 35.925 1   9.383  ? 515  ALA   A C    1 
ATOM   1793 O O    . ALA   A 1 122 ? 21.763 46.824 36.476 1   8.775  ? 515  ALA   A O    1 
ATOM   1794 C CB   . ALA   A 1 122 ? 21.035 44.943 33.81  1   9.255  ? 515  ALA   A CB   1 
ATOM   1795 H H    . ALA   A 1 122 ? 22.258 47.647 34.501 1   9.126  ? 515  ALA   A H    1 
ATOM   1796 H HA   . ALA   A 1 122 ? 19.778 46.56  34.158 1   9.148  ? 515  ALA   A HA   1 
ATOM   1797 H HB1  . ALA   A 1 122 ? 20.832 44.946 32.86  1   9.22   ? 515  ALA   A HB1  1 
ATOM   1798 H HB2  . ALA   A 1 122 ? 21.98  44.751 33.935 1   9.22   ? 515  ALA   A HB2  1 
ATOM   1799 H HB3  . ALA   A 1 122 ? 20.508 44.255 34.249 1   9.217  ? 515  ALA   A HB3  1 
ATOM   1800 N N    . PRO   A 1 123 ? 19.884 45.576 36.631 1   8.963  ? 516  PRO   A N    1 
ATOM   1801 C CA   . PRO   A 1 123 ? 20.071 45.279 38.054 1   8.89   ? 516  PRO   A CA   1 
ATOM   1802 C C    . PRO   A 1 123 ? 21.112 44.188 38.274 1   9.262  ? 516  PRO   A C    1 
ATOM   1803 O O    . PRO   A 1 123 ? 20.805 43.043 38.646 1   9.647  ? 516  PRO   A O    1 
ATOM   1804 C CB   . PRO   A 1 123 ? 18.653 45.018 38.536 1   8.308  ? 516  PRO   A CB   1 
ATOM   1805 C CG   . PRO   A 1 123 ? 17.96  44.423 37.312 1   8.748  ? 516  PRO   A CG   1 
ATOM   1806 C CD   . PRO   A 1 123 ? 18.536 45.214 36.15  1   8.707  ? 516  PRO   A CD   1 
ATOM   1807 H HA   . PRO   A 1 123 ? 20.385 46.093 38.501 1   8.866  ? 516  PRO   A HA   1 
ATOM   1808 H HB2  . PRO   A 1 123 ? 18.647 44.389 39.283 1   8.551  ? 516  PRO   A HB2  1 
ATOM   1809 H HB3  . PRO   A 1 123 ? 18.221 45.848 38.814 1   8.538  ? 516  PRO   A HB3  1 
ATOM   1810 H HG2  . PRO   A 1 123 ? 18.164 43.472 37.219 1   8.651  ? 516  PRO   A HG2  1 
ATOM   1811 H HG3  . PRO   A 1 123 ? 16.991 44.539 37.366 1   8.648  ? 516  PRO   A HG3  1 
ATOM   1812 H HD2  . PRO   A 1 123 ? 18.588 44.67  35.342 1   8.782  ? 516  PRO   A HD2  1 
ATOM   1813 H HD3  . PRO   A 1 123 ? 18.006 46.015 35.968 1   8.776  ? 516  PRO   A HD3  1 
ATOM   1814 N N    . LEU   A 1 124 ? 22.361 44.577 38.004 1   9.757  ? 517  LEU   A N    1 
ATOM   1815 C CA   . LEU   A 1 124 ? 23.484 43.651 37.945 1   9.739  ? 517  LEU   A CA   1 
ATOM   1816 C C    . LEU   A 1 124 ? 24.251 43.724 39.257 1   9.839  ? 517  LEU   A C    1 
ATOM   1817 O O    . LEU   A 1 124 ? 24.735 44.807 39.585 1   10.168 ? 517  LEU   A O    1 
ATOM   1818 C CB   . LEU   A 1 124 ? 24.415 44.07  36.824 1   10.156 ? 517  LEU   A CB   1 
ATOM   1819 C CG   . LEU   A 1 124 ? 25.644 43.179 36.639 1   9.874  ? 517  LEU   A CG   1 
ATOM   1820 C CD1  . LEU   A 1 124 ? 25.201 41.843 36.025 1   9.459  ? 517  LEU   A CD1  1 
ATOM   1821 C CD2  . LEU   A 1 124 ? 26.692 43.856 35.801 1   11.352 ? 517  LEU   A CD2  1 
ATOM   1822 H H    . LEU   A 1 124 ? 22.525 45.465 37.864 1   9.623  ? 517  LEU   A H    1 
ATOM   1823 H HA   . LEU   A 1 124 ? 23.15  42.732 37.789 1   9.825  ? 517  LEU   A HA   1 
ATOM   1824 H HB2  . LEU   A 1 124 ? 23.903 44.075 35.983 1   9.99   ? 517  LEU   A HB2  1 
ATOM   1825 H HB3  . LEU   A 1 124 ? 24.718 44.99  37     1   10.001 ? 517  LEU   A HB3  1 
ATOM   1826 H HG   . LEU   A 1 124 ? 26.037 42.995 37.531 1   10.11  ? 517  LEU   A HG   1 
ATOM   1827 H HD11 . LEU   A 1 124 ? 24.663 41.352 36.667 1   9.582  ? 517  LEU   A HD11 1 
ATOM   1828 H HD12 . LEU   A 1 124 ? 25.985 41.318 35.792 1   9.58   ? 517  LEU   A HD12 1 
ATOM   1829 H HD13 . LEU   A 1 124 ? 24.676 42.011 35.224 1   9.582  ? 517  LEU   A HD13 1 
ATOM   1830 H HD21 . LEU   A 1 124 ? 26.912 44.719 36.189 1   10.897 ? 517  LEU   A HD21 1 
ATOM   1831 H HD22 . LEU   A 1 124 ? 26.353 43.985 34.899 1   10.892 ? 517  LEU   A HD22 1 
ATOM   1832 H HD23 . LEU   A 1 124 ? 27.49  43.303 35.77  1   10.891 ? 517  LEU   A HD23 1 
ATOM   1833 N N    . THR   A 1 125 ? 24.334 42.593 39.973 1   9.535  ? 518  THR   A N    1 
ATOM   1834 C CA   . THR   A 1 125 ? 24.981 42.543 41.279 1   9.962  ? 518  THR   A CA   1 
ATOM   1835 C C    . THR   A 1 125 ? 26.491 42.714 41.111 1   11.376 ? 518  THR   A C    1 
ATOM   1836 O O    . THR   A 1 125 ? 27.124 42.063 40.273 1   11.814 ? 518  THR   A O    1 
ATOM   1837 C CB   . THR   A 1 125 ? 24.644 41.259 42.041 1   10.565 ? 518  THR   A CB   1 
ATOM   1838 O OG1  . THR   A 1 125 ? 23.271 41.388 42.406 1   10.198 ? 518  THR   A OG1  1 
ATOM   1839 C CG2  . THR   A 1 125 ? 25.502 41.041 43.28  1   10.61  ? 518  THR   A CG2  1 
ATOM   1840 H H    . THR   A 1 125 ? 23.974 41.824 39.635 1   9.714  ? 518  THR   A H    1 
ATOM   1841 H HA   . THR   A 1 125 ? 24.643 43.299 41.804 1   10.243 ? 518  THR   A HA   1 
ATOM   1842 H HB   . THR   A 1 125 ? 24.748 40.482 41.442 1   10.388 ? 518  THR   A HB   1 
ATOM   1843 H HG1  . THR   A 1 125 ? 23.166 42.069 42.907 0   30     ? 518  THR   A HG1  1 
ATOM   1844 H HG21 . THR   A 1 125 ? 25.028 40.468 43.906 1   10.595 ? 518  THR   A HG21 1 
ATOM   1845 H HG22 . THR   A 1 125 ? 25.687 41.896 43.703 1   10.59  ? 518  THR   A HG22 1 
ATOM   1846 H HG23 . THR   A 1 125 ? 26.339 40.618 43.026 1   10.598 ? 518  THR   A HG23 1 
ATOM   1847 N N    . ILE   A 1 126 ? 27.044 43.629 41.92  1   11.615 ? 519  ILE   A N    1 
ATOM   1848 C CA   . ILE   A 1 126 ? 28.473 43.821 42.086 1   12.265 ? 519  ILE   A CA   1 
ATOM   1849 C C    . ILE   A 1 126 ? 29.01  42.769 43.048 1   12.698 ? 519  ILE   A C    1 
ATOM   1850 O O    . ILE   A 1 126 ? 28.592 42.704 44.203 1   13.501 ? 519  ILE   A O    1 
ATOM   1851 C CB   . ILE   A 1 126 ? 28.753 45.234 42.626 1   11.966 ? 519  ILE   A CB   1 
ATOM   1852 C CG1  . ILE   A 1 126 ? 28.204 46.31  41.705 1   11.355 ? 519  ILE   A CG1  1 
ATOM   1853 C CG2  . ILE   A 1 126 ? 30.249 45.422 42.945 1   12.295 ? 519  ILE   A CG2  1 
ATOM   1854 C CD1  . ILE   A 1 126 ? 28.033 47.649 42.378 1   11.64  ? 519  ILE   A CD1  1 
ATOM   1855 H H    . ILE   A 1 126 ? 26.484 44.163 42.407 1   11.675 ? 519  ILE   A H    1 
ATOM   1856 H HA   . ILE   A 1 126 ? 28.91  43.72  41.218 1   12.176 ? 519  ILE   A HA   1 
ATOM   1857 H HB   . ILE   A 1 126 ? 28.269 45.313 43.473 1   11.956 ? 519  ILE   A HB   1 
ATOM   1858 H HG12 . ILE   A 1 126 ? 28.813 46.415 40.946 1   11.574 ? 519  ILE   A HG12 1 
ATOM   1859 H HG13 . ILE   A 1 126 ? 27.337 46.02  41.355 1   11.565 ? 519  ILE   A HG13 1 
ATOM   1860 H HG21 . ILE   A 1 126 ? 30.467 46.369 42.942 1   12.187 ? 519  ILE   A HG21 1 
ATOM   1861 H HG22 . ILE   A 1 126 ? 30.785 44.966 42.274 1   12.198 ? 519  ILE   A HG22 1 
ATOM   1862 H HG23 . ILE   A 1 126 ? 30.445 45.05  43.821 1   12.198 ? 519  ILE   A HG23 1 
ATOM   1863 H HD11 . ILE   A 1 126 ? 27.523 47.537 43.202 1   11.552 ? 519  ILE   A HD11 1 
ATOM   1864 H HD12 . ILE   A 1 126 ? 27.555 48.256 41.782 1   11.527 ? 519  ILE   A HD12 1 
ATOM   1865 H HD13 . ILE   A 1 126 ? 28.908 48.026 42.588 1   11.553 ? 519  ILE   A HD13 1 
ATOM   1866 N N    . ASN   A 1 127 ? 29.931 41.929 42.576 1   14.304 ? 520  ASN   A N    1 
ATOM   1867 C CA   . ASN   A 1 127 ? 30.618 40.973 43.455 1   15.266 ? 520  ASN   A CA   1 
ATOM   1868 C C    . ASN   A 1 127 ? 32.054 40.768 42.959 1   15.328 ? 520  ASN   A C    1 
ATOM   1869 O O    . ASN   A 1 127 ? 32.352 41.043 41.798 1   14.229 ? 520  ASN   A O    1 
ATOM   1870 C CB   . ASN   A 1 127 ? 29.817 39.677 43.639 1   16.89  ? 520  ASN   A CB   1 
ATOM   1871 C CG   . ASN   A 1 127 ? 29.563 38.915 42.353 1   18.662 ? 520  ASN   A CG   1 
ATOM   1872 O OD1  . ASN   A 1 127 ? 28.416 38.668 41.958 1   24.077 ? 520  ASN   A OD1  1 
ATOM   1873 N ND2  . ASN   A 1 127 ? 30.61  38.543 41.652 1   22.151 ? 520  ASN   A ND2  1 
ATOM   1874 H H    . ASN   A 1 127 ? 30.142 41.942 41.687 1   14.081 ? 520  ASN   A H    1 
ATOM   1875 H HA   . ASN   A 1 127 ? 30.682 41.389 44.345 1   15.354 ? 520  ASN   A HA   1 
ATOM   1876 H HB2  . ASN   A 1 127 ? 30.301 39.094 44.258 1   16.911 ? 520  ASN   A HB2  1 
ATOM   1877 H HB3  . ASN   A 1 127 ? 28.957 39.895 44.049 1   16.995 ? 520  ASN   A HB3  1 
ATOM   1878 H HD21 . ASN   A 1 127 ? 30.527 37.871 41.082 1   20.718 ? 520  ASN   A HD21 1 
ATOM   1879 H HD22 . ASN   A 1 127 ? 31.377 38.953 41.762 1   20.666 ? 520  ASN   A HD22 1 
ATOM   1880 N N    . ASN   A 1 128 ? 32.924 40.252 43.84  1   17.19  ? 521  ASN   A N    1 
ATOM   1881 C CA   A ASN   A 1 128 ? 34.335 40.139 43.512 0.5 18.32  ? 521  ASN   A CA   1 
ATOM   1882 C CA   B ASN   A 1 128 ? 34.347 40.034 43.588 0.5 19.017 ? 521  ASN   A CA   1 
ATOM   1883 C C    . ASN   A 1 128 ? 34.554 39.119 42.386 1   18.606 ? 521  ASN   A C    1 
ATOM   1884 O O    . ASN   A 1 128 ? 35.457 39.31  41.576 1   18.745 ? 521  ASN   A O    1 
ATOM   1885 C CB   A ASN   A 1 128 ? 35.184 39.906 44.761 0.5 18.469 ? 521  ASN   A CB   1 
ATOM   1886 C CB   B ASN   A 1 128 ? 35.062 39.398 44.783 0.5 20.042 ? 521  ASN   A CB   1 
ATOM   1887 C CG   A ASN   A 1 128 ? 35.379 41.174 45.569 0.5 19.681 ? 521  ASN   A CG   1 
ATOM   1888 C CG   B ASN   A 1 128 ? 36.509 39.032 44.5   0.5 23.005 ? 521  ASN   A CG   1 
ATOM   1889 O OD1  A ASN   A 1 128 ? 35.333 41.129 46.804 0.5 18     ? 521  ASN   A OD1  1 
ATOM   1890 O OD1  B ASN   A 1 128 ? 37.356 39.903 44.251 0.5 26.283 ? 521  ASN   A OD1  1 
ATOM   1891 N ND2  A ASN   A 1 128 ? 35.608 42.31  44.911 0.5 20.704 ? 521  ASN   A ND2  1 
ATOM   1892 N ND2  B ASN   A 1 128 ? 36.836 37.75  44.571 0.5 24.732 ? 521  ASN   A ND2  1 
ATOM   1893 H H    A ASN   A 1 128 ? 32.632 39.966 44.658 0.5 16.955 ? 521  ASN   A H    1 
ATOM   1894 H H    B ASN   A 1 128 ? 32.602 40.018 44.663 0.5 17.088 ? 521  ASN   A H    1 
ATOM   1895 H HA   A ASN   A 1 128 ? 34.613 41.012 43.154 0.5 18.11  ? 521  ASN   A HA   1 
ATOM   1896 H HA   B ASN   A 1 128 ? 34.771 40.903 43.408 0.5 18.754 ? 521  ASN   A HA   1 
ATOM   1897 H HB2  A ASN   A 1 128 ? 34.751 39.232 45.322 0.5 18.705 ? 521  ASN   A HB2  1 
ATOM   1898 H HB2  B ASN   A 1 128 ? 35.036 40.021 45.536 0.5 20.442 ? 521  ASN   A HB2  1 
ATOM   1899 H HB3  A ASN   A 1 128 ? 36.059 39.559 44.494 0.5 18.705 ? 521  ASN   A HB3  1 
ATOM   1900 H HB3  B ASN   A 1 128 ? 34.578 38.59  45.048 0.5 20.442 ? 521  ASN   A HB3  1 
ATOM   1901 H HD21 A ASN   A 1 128 ? 35.732 43.065 45.36  0.5 20.384 ? 521  ASN   A HD21 1 
ATOM   1902 H HD21 B ASN   A 1 128 ? 37.683 37.515 44.689 0.5 24.187 ? 521  ASN   A HD21 1 
ATOM   1903 H HD22 A ASN   A 1 128 ? 35.636 42.31  44.024 0.5 20.384 ? 521  ASN   A HD22 1 
ATOM   1904 H HD22 B ASN   A 1 128 ? 36.207 37.129 44.501 0.5 24.187 ? 521  ASN   A HD22 1 
ATOM   1905 N N    . GLU   A 1 129 ? 33.751 38.056 42.302 1   18.501 ? 522  GLU   A N    1 
ATOM   1906 C CA   A GLU   A 1 129 ? 33.942 37.059 41.259 0.5 18.58  ? 522  GLU   A CA   1 
ATOM   1907 C CA   B GLU   A 1 129 ? 33.964 37.065 41.255 0.5 18.886 ? 522  GLU   A CA   1 
ATOM   1908 C C    . GLU   A 1 129 ? 33.855 37.728 39.883 1   17.871 ? 522  GLU   A C    1 
ATOM   1909 O O    . GLU   A 1 129 ? 34.699 37.531 38.985 1   15.898 ? 522  GLU   A O    1 
ATOM   1910 C CB   A GLU   A 1 129 ? 32.917 35.946 41.489 0.5 19.237 ? 522  GLU   A CB   1 
ATOM   1911 C CB   B GLU   A 1 129 ? 33.002 35.876 41.302 0.5 20.052 ? 522  GLU   A CB   1 
ATOM   1912 C CG   A GLU   A 1 129 ? 33.164 35.141 42.764 0.5 20.393 ? 522  GLU   A CG   1 
ATOM   1913 C CG   B GLU   A 1 129 ? 33.29  34.908 40.159 0.5 21.602 ? 522  GLU   A CG   1 
ATOM   1914 C CD   A GLU   A 1 129 ? 32.708 35.694 44.115 0.5 20.773 ? 522  GLU   A CD   1 
ATOM   1915 C CD   B GLU   A 1 129 ? 32.558 33.585 40.11  0.5 23.194 ? 522  GLU   A CD   1 
ATOM   1916 O OE1  A GLU   A 1 129 ? 31.997 36.71  44.253 0.5 18.416 ? 522  GLU   A OE1  1 
ATOM   1917 O OE1  B GLU   A 1 129 ? 31.658 33.271 40.923 0.5 26.351 ? 522  GLU   A OE1  1 
ATOM   1918 O OE2  A GLU   A 1 129 ? 33.108 35.032 45.092 0.5 23.15  ? 522  GLU   A OE2  1 
ATOM   1919 O OE2  B GLU   A 1 129 ? 32.937 32.852 39.186 0.5 23.594 ? 522  GLU   A OE2  1 
ATOM   1920 H H    A GLU   A 1 129 ? 33.08  37.939 42.912 0.5 18.55  ? 522  GLU   A H    1 
ATOM   1921 H H    B GLU   A 1 129 ? 33.075 37.935 42.905 0.5 18.617 ? 522  GLU   A H    1 
ATOM   1922 H HA   A GLU   A 1 129 ? 34.85  36.675 41.362 0.5 18.551 ? 522  GLU   A HA   1 
ATOM   1923 H HA   B GLU   A 1 129 ? 34.885 36.712 41.354 0.5 18.825 ? 522  GLU   A HA   1 
ATOM   1924 H HB2  A GLU   A 1 129 ? 32.024 36.342 41.535 0.5 19.365 ? 522  GLU   A HB2  1 
ATOM   1925 H HB2  B GLU   A 1 129 ? 33.101 35.416 42.162 0.5 20.118 ? 522  GLU   A HB2  1 
ATOM   1926 H HB3  A GLU   A 1 129 ? 32.935 35.338 40.721 0.5 19.345 ? 522  GLU   A HB3  1 
ATOM   1927 H HB3  B GLU   A 1 129 ? 32.082 36.204 41.238 0.5 20.121 ? 522  GLU   A HB3  1 
ATOM   1928 H HG2  A GLU   A 1 129 ? 32.742 34.262 42.651 0.5 20.208 ? 522  GLU   A HG2  1 
ATOM   1929 H HG2  B GLU   A 1 129 ? 33.109 35.371 39.314 0.5 21.491 ? 522  GLU   A HG2  1 
ATOM   1930 H HG3  A GLU   A 1 129 ? 34.128 34.97  42.829 0.5 20.208 ? 522  GLU   A HG3  1 
ATOM   1931 H HG3  B GLU   A 1 129 ? 34.251 34.712 40.163 0.5 21.572 ? 522  GLU   A HG3  1 
ATOM   1932 N N    . ARG   A 1 130 ? 32.807 38.528 39.704 1   14.941 ? 523  ARG   A N    1 
ATOM   1933 C CA   . ARG   A 1 130 ? 32.614 39.236 38.453 1   14.657 ? 523  ARG   A CA   1 
ATOM   1934 C C    . ARG   A 1 130 ? 33.686 40.303 38.27  1   14.318 ? 523  ARG   A C    1 
ATOM   1935 O O    . ARG   A 1 130 ? 34.157 40.518 37.147 1   14.815 ? 523  ARG   A O    1 
ATOM   1936 C CB   . ARG   A 1 130 ? 31.223 39.878 38.389 1   12.757 ? 523  ARG   A CB   1 
ATOM   1937 C CG   . ARG   A 1 130 ? 30.162 38.79  38.259 1   11.621 ? 523  ARG   A CG   1 
ATOM   1938 C CD   . ARG   A 1 130 ? 28.76  39.401 38.295 1   11.56  ? 523  ARG   A CD   1 
ATOM   1939 N NE   . ARG   A 1 130 ? 27.686 38.498 37.865 1   11.655 ? 523  ARG   A NE   1 
ATOM   1940 C CZ   . ARG   A 1 130 ? 26.378 38.69  38.145 1   11.544 ? 523  ARG   A CZ   1 
ATOM   1941 N NH1  . ARG   A 1 130 ? 26.001 39.798 38.767 1   10.468 ? 523  ARG   A NH1  1 
ATOM   1942 N NH2  . ARG   A 1 130 ? 25.474 37.782 37.776 1   11.033 ? 523  ARG   A NH2  1 
ATOM   1943 H H    . ARG   A 1 130 ? 32.208 38.651 40.378 1   15.689 ? 523  ARG   A H    1 
ATOM   1944 H HA   . ARG   A 1 130 ? 32.691 38.583 37.711 1   14.292 ? 523  ARG   A HA   1 
ATOM   1945 H HB2  . ARG   A 1 130 ? 31.06  40.399 39.204 1   12.906 ? 523  ARG   A HB2  1 
ATOM   1946 H HB3  . ARG   A 1 130 ? 31.169 40.482 37.618 1   12.897 ? 523  ARG   A HB3  1 
ATOM   1947 H HG2  . ARG   A 1 130 ? 30.285 38.313 37.409 1   11.893 ? 523  ARG   A HG2  1 
ATOM   1948 H HG3  . ARG   A 1 130 ? 30.255 38.146 38.992 1   11.969 ? 523  ARG   A HG3  1 
ATOM   1949 H HD2  . ARG   A 1 130 ? 28.58  39.696 39.211 1   11.591 ? 523  ARG   A HD2  1 
ATOM   1950 H HD3  . ARG   A 1 130 ? 28.754 40.196 37.724 1   11.601 ? 523  ARG   A HD3  1 
ATOM   1951 H HE   . ARG   A 1 130 ? 27.903 37.794 37.401 1   11.6   ? 523  ARG   A HE   1 
ATOM   1952 H HH11 . ARG   A 1 130 ? 26.185 40.587 38.414 1   10.784 ? 523  ARG   A HH11 1 
ATOM   1953 H HH12 . ARG   A 1 130 ? 25.565 39.74  39.532 1   10.783 ? 523  ARG   A HH12 1 
ATOM   1954 H HH21 . ARG   A 1 130 ? 25.577 37.344 37.015 1   11.19  ? 523  ARG   A HH21 1 
ATOM   1955 H HH22 . ARG   A 1 130 ? 24.775 37.622 38.293 1   11.184 ? 523  ARG   A HH22 1 
ATOM   1956 N N    . ALA   A 1 131 ? 34.02  41     39.356 1   14.437 ? 524  ALA   A N    1 
ATOM   1957 C CA   . ALA   A 1 131 ? 34.979 42.099 39.286 1   14.678 ? 524  ALA   A CA   1 
ATOM   1958 C C    . ALA   A 1 131 ? 36.371 41.614 38.86  1   15.284 ? 524  ALA   A C    1 
ATOM   1959 O O    . ALA   A 1 131 ? 37.187 42.402 38.413 1   16.487 ? 524  ALA   A O    1 
ATOM   1960 C CB   . ALA   A 1 131 ? 35.017 42.845 40.604 1   14.172 ? 524  ALA   A CB   1 
ATOM   1961 H H    . ALA   A 1 131 ? 33.64  40.795 40.162 1   14.483 ? 524  ALA   A H    1 
ATOM   1962 H HA   . ALA   A 1 131 ? 34.656 42.729 38.585 1   14.651 ? 524  ALA   A HA   1 
ATOM   1963 H HB1  . ALA   A 1 131 ? 34.118 43.12  40.851 1   14.325 ? 524  ALA   A HB1  1 
ATOM   1964 H HB2  . ALA   A 1 131 ? 35.378 42.267 41.296 1   14.343 ? 524  ALA   A HB2  1 
ATOM   1965 H HB3  . ALA   A 1 131 ? 35.58  43.633 40.517 1   14.325 ? 524  ALA   A HB3  1 
ATOM   1966 N N    . GLN   A 1 132 ? 36.652 40.317 38.958 1   16.273 ? 525  GLN   A N    1 
ATOM   1967 C CA   . GLN   A 1 132 ? 37.887 39.78  38.396 1   17.491 ? 525  GLN   A CA   1 
ATOM   1968 C C    . GLN   A 1 132 ? 37.959 39.88  36.874 1   17.868 ? 525  GLN   A C    1 
ATOM   1969 O O    . GLN   A 1 132 ? 39.054 39.86  36.297 1   18.191 ? 525  GLN   A O    1 
ATOM   1970 C CB   . GLN   A 1 132 ? 38.001 38.317 38.795 1   18.073 ? 525  GLN   A CB   1 
ATOM   1971 C CG   . GLN   A 1 132 ? 38.258 38.12  40.279 1   19.615 ? 525  GLN   A CG   1 
ATOM   1972 C CD   . GLN   A 1 132 ? 38.419 36.664 40.643 1   21.185 ? 525  GLN   A CD   1 
ATOM   1973 O OE1  . GLN   A 1 132 ? 38.579 35.787 39.782 1   23.834 ? 525  GLN   A OE1  1 
ATOM   1974 N NE2  . GLN   A 1 132 ? 38.424 36.416 41.939 1   23.161 ? 525  GLN   A NE2  1 
ATOM   1975 H H    . GLN   A 1 132 ? 36.082 39.755 39.398 1   16.319 ? 525  GLN   A H    1 
ATOM   1976 H HA   . GLN   A 1 132 ? 38.651 40.277 38.782 1   17.403 ? 525  GLN   A HA   1 
ATOM   1977 H HB2  . GLN   A 1 132 ? 37.174 37.855 38.548 1   18.277 ? 525  GLN   A HB2  1 
ATOM   1978 H HB3  . GLN   A 1 132 ? 38.734 37.908 38.288 1   18.3   ? 525  GLN   A HB3  1 
ATOM   1979 H HG2  . GLN   A 1 132 ? 39.069 38.606 40.534 1   19.588 ? 525  GLN   A HG2  1 
ATOM   1980 H HG3  . GLN   A 1 132 ? 37.513 38.494 40.791 1   19.551 ? 525  GLN   A HG3  1 
ATOM   1981 H HE21 . GLN   A 1 132 ? 38.041 35.679 42.249 1   22.528 ? 525  GLN   A HE21 1 
ATOM   1982 H HE22 . GLN   A 1 132 ? 38.812 36.985 42.498 1   22.512 ? 525  GLN   A HE22 1 
ATOM   1983 N N    . TYR   A 1 133 ? 36.798 39.966 36.222 1   17.051 ? 526  TYR   A N    1 
ATOM   1984 C CA   . TYR   A 1 133 ? 36.722 39.899 34.777 1   17.708 ? 526  TYR   A CA   1 
ATOM   1985 C C    . TYR   A 1 133 ? 36.266 41.218 34.179 1   17.836 ? 526  TYR   A C    1 
ATOM   1986 O O    . TYR   A 1 133 ? 36.641 41.524 33.044 1   16.91  ? 526  TYR   A O    1 
ATOM   1987 C CB   . TYR   A 1 133 ? 35.785 38.756 34.387 1   19.269 ? 526  TYR   A CB   1 
ATOM   1988 C CG   . TYR   A 1 133 ? 36.406 37.418 34.721 1   21.271 ? 526  TYR   A CG   1 
ATOM   1989 C CD1  . TYR   A 1 133 ? 36.256 36.871 35.984 1   24.411 ? 526  TYR   A CD1  1 
ATOM   1990 C CD2  . TYR   A 1 133 ? 37.21  36.744 33.805 1   24.839 ? 526  TYR   A CD2  1 
ATOM   1991 C CE1  . TYR   A 1 133 ? 36.842 35.659 36.312 1   27.079 ? 526  TYR   A CE1  1 
ATOM   1992 C CE2  . TYR   A 1 133 ? 37.804 35.533 34.122 1   25.895 ? 526  TYR   A CE2  1 
ATOM   1993 C CZ   . TYR   A 1 133 ? 37.614 34.986 35.377 1   29.366 ? 526  TYR   A CZ   1 
ATOM   1994 O OH   . TYR   A 1 133 ? 38.195 33.785 35.701 1   32.721 ? 526  TYR   A OH   1 
ATOM   1995 H H    . TYR   A 1 133 ? 36.021 40.036 36.696 1   17.337 ? 526  TYR   A H    1 
ATOM   1996 H HA   . TYR   A 1 133 ? 37.627 39.693 34.423 1   17.893 ? 526  TYR   A HA   1 
ATOM   1997 H HB2  . TYR   A 1 133 ? 34.938 38.855 34.874 1   19.334 ? 526  TYR   A HB2  1 
ATOM   1998 H HB3  . TYR   A 1 133 ? 35.607 38.802 33.421 1   19.328 ? 526  TYR   A HB3  1 
ATOM   1999 H HD1  . TYR   A 1 133 ? 35.725 37.318 36.624 1   24.185 ? 526  TYR   A HD1  1 
ATOM   2000 H HD2  . TYR   A 1 133 ? 37.337 37.109 32.944 1   24.23  ? 526  TYR   A HD2  1 
ATOM   2001 H HE1  . TYR   A 1 133 ? 36.712 35.287 37.168 1   26.886 ? 526  TYR   A HE1  1 
ATOM   2002 H HE2  . TYR   A 1 133 ? 38.326 35.079 33.483 1   26.38  ? 526  TYR   A HE2  1 
ATOM   2003 H HH   . TYR   A 1 133 ? 37.985 33.57  36.528 0   30     ? 526  TYR   A HH   1 
ATOM   2004 N N    . ILE   A 1 134 ? 35.437 41.978 34.92  1   16.301 ? 527  ILE   A N    1 
ATOM   2005 C CA   . ILE   A 1 134 ? 34.92  43.236 34.404 1   15.805 ? 527  ILE   A CA   1 
ATOM   2006 C C    . ILE   A 1 134 ? 35.111 44.332 35.444 1   15.569 ? 527  ILE   A C    1 
ATOM   2007 O O    . ILE   A 1 134 ? 35.518 44.064 36.571 1   16.096 ? 527  ILE   A O    1 
ATOM   2008 C CB   . ILE   A 1 134 ? 33.436 43.125 34     1   15.145 ? 527  ILE   A CB   1 
ATOM   2009 C CG1  . ILE   A 1 134 ? 32.516 42.988 35.222 1   14.38  ? 527  ILE   A CG1  1 
ATOM   2010 C CG2  . ILE   A 1 134 ? 33.216 41.995 32.995 1   16.162 ? 527  ILE   A CG2  1 
ATOM   2011 C CD1  . ILE   A 1 134 ? 31.095 43.469 34.954 1   14.901 ? 527  ILE   A CD1  1 
ATOM   2012 H H    . ILE   A 1 134 ? 35.182 41.704 35.754 1   16.552 ? 527  ILE   A H    1 
ATOM   2013 H HA   . ILE   A 1 134 ? 35.434 43.478 33.61  1   15.752 ? 527  ILE   A HA   1 
ATOM   2014 H HB   . ILE   A 1 134 ? 33.195 43.959 33.552 1   15.298 ? 527  ILE   A HB   1 
ATOM   2015 H HG12 . ILE   A 1 134 ? 32.487 42.048 35.492 1   14.672 ? 527  ILE   A HG12 1 
ATOM   2016 H HG13 . ILE   A 1 134 ? 32.888 43.504 35.965 1   14.68  ? 527  ILE   A HG13 1 
ATOM   2017 H HG21 . ILE   A 1 134 ? 32.283 41.979 32.722 1   15.816 ? 527  ILE   A HG21 1 
ATOM   2018 H HG22 . ILE   A 1 134 ? 33.445 41.144 33.405 1   15.857 ? 527  ILE   A HG22 1 
ATOM   2019 H HG23 . ILE   A 1 134 ? 33.777 42.139 32.215 1   15.849 ? 527  ILE   A HG23 1 
ATOM   2020 H HD11 . ILE   A 1 134 ? 31.111 44.412 34.7   1   14.745 ? 527  ILE   A HD11 1 
ATOM   2021 H HD12 . ILE   A 1 134 ? 30.555 43.36  35.76  1   14.739 ? 527  ILE   A HD12 1 
ATOM   2022 H HD13 . ILE   A 1 134 ? 30.703 42.946 34.229 1   14.748 ? 527  ILE   A HD13 1 
ATOM   2023 N N    . GLU   A 1 135 ? 34.748 45.549 35.048 1   16.121 ? 528  GLU   A N    1 
ATOM   2024 C CA   . GLU   A 1 135 ? 34.69  46.678 35.965 1   17.705 ? 528  GLU   A CA   1 
ATOM   2025 C C    . GLU   A 1 135 ? 33.243 47.112 36.225 1   15.132 ? 528  GLU   A C    1 
ATOM   2026 O O    . GLU   A 1 135 ? 32.382 47.108 35.339 1   14.691 ? 528  GLU   A O    1 
ATOM   2027 C CB   . GLU   A 1 135 ? 35.556 47.829 35.467 1   21.201 ? 528  GLU   A CB   1 
ATOM   2028 C CG   . GLU   A 1 135 ? 36.891 47.874 36.204 1   28.127 ? 528  GLU   A CG   1 
ATOM   2029 C CD   . GLU   A 1 135 ? 37.962 48.602 35.427 1   34.718 ? 528  GLU   A CD   1 
ATOM   2030 O OE1  . GLU   A 1 135 ? 37.655 49.646 34.804 1   37.656 ? 528  GLU   A OE1  1 
ATOM   2031 O OE2  . GLU   A 1 135 ? 39.098 48.083 35.435 1   42.677 ? 528  GLU   A OE2  1 
ATOM   2032 H H    . GLU   A 1 135 ? 34.536 45.688 34.17  1   16.346 ? 528  GLU   A H    1 
ATOM   2033 H HA   . GLU   A 1 135 ? 35.07  46.382 36.83  1   17.5   ? 528  GLU   A HA   1 
ATOM   2034 H HB2  . GLU   A 1 135 ? 35.712 47.721 34.505 1   21.667 ? 528  GLU   A HB2  1 
ATOM   2035 H HB3  . GLU   A 1 135 ? 35.079 48.674 35.603 1   21.651 ? 528  GLU   A HB3  1 
ATOM   2036 H HG2  . GLU   A 1 135 ? 36.769 48.322 37.068 1   27.675 ? 528  GLU   A HG2  1 
ATOM   2037 H HG3  . GLU   A 1 135 ? 37.197 46.958 36.378 1   27.607 ? 528  GLU   A HG3  1 
ATOM   2038 N N    . PHE   A 1 136 ? 33.003 47.504 37.478 1   13.612 ? 529  PHE   A N    1 
ATOM   2039 C CA   . PHE   A 1 136 ? 31.718 48.046 37.883 1   13.235 ? 529  PHE   A CA   1 
ATOM   2040 C C    . PHE   A 1 136 ? 31.865 49.52  38.197 1   13.048 ? 529  PHE   A C    1 
ATOM   2041 O O    . PHE   A 1 136 ? 32.881 49.921 38.765 1   14.134 ? 529  PHE   A O    1 
ATOM   2042 C CB   . PHE   A 1 136 ? 31.178 47.365 39.139 1   12.776 ? 529  PHE   A CB   1 
ATOM   2043 C CG   . PHE   A 1 136 ? 30.802 45.913 38.964 1   13.607 ? 529  PHE   A CG   1 
ATOM   2044 C CD1  . PHE   A 1 136 ? 29.575 45.568 38.405 1   13.298 ? 529  PHE   A CD1  1 
ATOM   2045 C CD2  . PHE   A 1 136 ? 31.684 44.897 39.324 1   13.181 ? 529  PHE   A CD2  1 
ATOM   2046 C CE1  . PHE   A 1 136 ? 29.234 44.239 38.264 1   13.107 ? 529  PHE   A CE1  1 
ATOM   2047 C CE2  . PHE   A 1 136 ? 31.323 43.561 39.173 1   13.21  ? 529  PHE   A CE2  1 
ATOM   2048 C CZ   . PHE   A 1 136 ? 30.125 43.241 38.621 1   13.212 ? 529  PHE   A CZ   1 
ATOM   2049 H H    . PHE   A 1 136 ? 33.664 47.433 38.105 1   13.925 ? 529  PHE   A H    1 
ATOM   2050 H HA   . PHE   A 1 136 ? 31.067 47.93  37.145 1   13.181 ? 529  PHE   A HA   1 
ATOM   2051 H HB2  . PHE   A 1 136 ? 31.859 47.432 39.845 1   13.064 ? 529  PHE   A HB2  1 
ATOM   2052 H HB3  . PHE   A 1 136 ? 30.385 47.86  39.444 1   13.051 ? 529  PHE   A HB3  1 
ATOM   2053 H HD1  . PHE   A 1 136 ? 28.964 46.243 38.156 1   13.317 ? 529  PHE   A HD1  1 
ATOM   2054 H HD2  . PHE   A 1 136 ? 32.521 45.117 39.702 1   13.28  ? 529  PHE   A HD2  1 
ATOM   2055 H HE1  . PHE   A 1 136 ? 28.401 44.009 37.887 1   13.148 ? 529  PHE   A HE1  1 
ATOM   2056 H HE2  . PHE   A 1 136 ? 31.927 42.879 39.419 1   13.205 ? 529  PHE   A HE2  1 
ATOM   2057 H HZ   . PHE   A 1 136 ? 29.881 42.335 38.517 1   13.184 ? 529  PHE   A HZ   1 
ATOM   2058 N N    . SER   A 1 137 ? 30.823 50.288 37.889 1   11.827 ? 530  SER   A N    1 
ATOM   2059 C CA   . SER   A 1 137 ? 30.613 51.58  38.518 1   11.671 ? 530  SER   A CA   1 
ATOM   2060 C C    . SER   A 1 137 ? 30.412 51.393 40.031 1   11.796 ? 530  SER   A C    1 
ATOM   2061 O O    . SER   A 1 137 ? 30.164 50.281 40.518 1   10.399 ? 530  SER   A O    1 
ATOM   2062 C CB   . SER   A 1 137 ? 29.423 52.279 37.917 1   11.517 ? 530  SER   A CB   1 
ATOM   2063 O OG   . SER   A 1 137 ? 28.239 51.637 38.373 1   10.44  ? 530  SER   A OG   1 
ATOM   2064 H H    . SER   A 1 137 ? 30.222 50     37.264 1   12.078 ? 530  SER   A H    1 
ATOM   2065 H HA   . SER   A 1 137 ? 31.419 52.137 38.371 1   11.71  ? 530  SER   A HA   1 
ATOM   2066 H HB2  . SER   A 1 137 ? 29.418 53.216 38.19  1   11.289 ? 530  SER   A HB2  1 
ATOM   2067 H HB3  . SER   A 1 137 ? 29.471 52.232 36.944 1   11.306 ? 530  SER   A HB3  1 
ATOM   2068 H HG   . SER   A 1 137 ? 27.576 52.039 38.019 0   30     ? 530  SER   A HG   1 
ATOM   2069 N N    . LYS   A 1 138 ? 30.468 52.503 40.768 1   11.284 ? 531  LYS   A N    1 
ATOM   2070 C CA   . LYS   A 1 138 ? 29.889 52.525 42.102 1   12.333 ? 531  LYS   A CA   1 
ATOM   2071 C C    . LYS   A 1 138 ? 28.426 52.106 42.033 1   11.435 ? 531  LYS   A C    1 
ATOM   2072 O O    . LYS   A 1 138 ? 27.78  52.289 41     1   10.737 ? 531  LYS   A O    1 
ATOM   2073 C CB   . LYS   A 1 138 ? 30.064 53.891 42.757 1   14.362 ? 531  LYS   A CB   1 
ATOM   2074 C CG   . LYS   A 1 138 ? 31.504 54.127 43.253 1   17.519 ? 531  LYS   A CG   1 
ATOM   2075 C CD   . LYS   A 1 138 ? 32.015 53.014 44.183 1   20.921 ? 531  LYS   A CD   1 
ATOM   2076 C CE   . LYS   A 1 138 ? 33.445 53.072 44.627 1   23.484 ? 531  LYS   A CE   1 
ATOM   2077 N NZ   . LYS   A 1 138 ? 34.138 54.029 43.773 1   25.747 ? 531  LYS   A NZ   1 
ATOM   2078 H H    . LYS   A 1 138 ? 30.87  53.255 40.439 1   11.67  ? 531  LYS   A H    1 
ATOM   2079 H HA   . LYS   A 1 138 ? 30.369 51.855 42.642 1   12.342 ? 531  LYS   A HA   1 
ATOM   2080 H HB2  . LYS   A 1 138 ? 29.832 54.591 42.11  1   14.494 ? 531  LYS   A HB2  1 
ATOM   2081 H HB3  . LYS   A 1 138 ? 29.451 53.966 43.518 1   14.463 ? 531  LYS   A HB3  1 
ATOM   2082 H HG2  . LYS   A 1 138 ? 32.092 54.192 42.469 1   17.575 ? 531  LYS   A HG2  1 
ATOM   2083 H HG3  . LYS   A 1 138 ? 31.535 54.985 43.729 1   17.503 ? 531  LYS   A HG3  1 
ATOM   2084 H HD2  . LYS   A 1 138 ? 31.445 53.008 44.982 1   20.614 ? 531  LYS   A HD2  1 
ATOM   2085 H HD3  . LYS   A 1 138 ? 31.875 52.153 43.736 1   20.491 ? 531  LYS   A HD3  1 
ATOM   2086 H HE2  . LYS   A 1 138 ? 33.504 53.359 45.555 1   23.381 ? 531  LYS   A HE2  1 
ATOM   2087 H HE3  . LYS   A 1 138 ? 33.862 52.196 44.54  1   23.381 ? 531  LYS   A HE3  1 
ATOM   2088 H HZ1  . LYS   A 1 138 ? 33.794 54.861 43.872 1   24.785 ? 531  LYS   A HZ1  1 
ATOM   2089 H HZ2  . LYS   A 1 138 ? 34.096 53.773 42.905 1   24.828 ? 531  LYS   A HZ2  1 
ATOM   2090 H HZ3  . LYS   A 1 138 ? 35.01  54.055 44.016 1   24.944 ? 531  LYS   A HZ3  1 
ATOM   2091 N N    . PRO   A 1 139 ? 27.856 51.56  43.127 1   10.015 ? 532  PRO   A N    1 
ATOM   2092 C CA   . PRO   A 1 139 ? 26.459 51.146 43.103 1   10.324 ? 532  PRO   A CA   1 
ATOM   2093 C C    . PRO   A 1 139 ? 25.512 52.287 42.737 1   10.196 ? 532  PRO   A C    1 
ATOM   2094 O O    . PRO   A 1 139 ? 25.582 53.382 43.318 1   9.904  ? 532  PRO   A O    1 
ATOM   2095 C CB   . PRO   A 1 139 ? 26.218 50.648 44.531 1   10.52  ? 532  PRO   A CB   1 
ATOM   2096 C CG   . PRO   A 1 139 ? 27.601 50.361 45.082 1   10.116 ? 532  PRO   A CG   1 
ATOM   2097 C CD   . PRO   A 1 139 ? 28.515 51.315 44.415 1   9.862  ? 532  PRO   A CD   1 
ATOM   2098 H HA   . PRO   A 1 139 ? 26.352 50.409 42.472 1   10.265 ? 532  PRO   A HA   1 
ATOM   2099 H HB2  . PRO   A 1 139 ? 25.767 51.33  45.066 1   10.384 ? 532  PRO   A HB2  1 
ATOM   2100 H HB3  . PRO   A 1 139 ? 25.67  49.84  44.529 1   10.374 ? 532  PRO   A HB3  1 
ATOM   2101 H HG2  . PRO   A 1 139 ? 27.62  50.492 46.051 1   10.157 ? 532  PRO   A HG2  1 
ATOM   2102 H HG3  . PRO   A 1 139 ? 27.866 49.441 44.885 1   10.148 ? 532  PRO   A HG3  1 
ATOM   2103 H HD2  . PRO   A 1 139 ? 28.6   52.143 44.925 1   9.962  ? 532  PRO   A HD2  1 
ATOM   2104 H HD3  . PRO   A 1 139 ? 29.399 50.922 44.286 1   9.983  ? 532  PRO   A HD3  1 
ATOM   2105 N N    . PHE   A 1 140 ? 24.582 51.996 41.821 1   10.111 ? 533  PHE   A N    1 
ATOM   2106 C CA   . PHE   A 1 140 ? 23.492 52.92  41.561 1   9.984  ? 533  PHE   A CA   1 
ATOM   2107 C C    . PHE   A 1 140 ? 22.326 52.604 42.493 1   9.183  ? 533  PHE   A C    1 
ATOM   2108 O O    . PHE   A 1 140 ? 21.388 53.39  42.597 1   8.879  ? 533  PHE   A O    1 
ATOM   2109 C CB   . PHE   A 1 140 ? 23.083 52.927 40.088 1   9.996  ? 533  PHE   A CB   1 
ATOM   2110 C CG   . PHE   A 1 140 ? 22.426 51.661 39.547 1   9.355  ? 533  PHE   A CG   1 
ATOM   2111 C CD1  . PHE   A 1 140 ? 21.094 51.347 39.844 1   9.458  ? 533  PHE   A CD1  1 
ATOM   2112 C CD2  . PHE   A 1 140 ? 23.132 50.798 38.715 1   8.553  ? 533  PHE   A CD2  1 
ATOM   2113 C CE1  . PHE   A 1 140 ? 20.495 50.187 39.315 1   9.434  ? 533  PHE   A CE1  1 
ATOM   2114 C CE2  . PHE   A 1 140 ? 22.521 49.68  38.165 1   8.605  ? 533  PHE   A CE2  1 
ATOM   2115 C CZ   . PHE   A 1 140 ? 21.226 49.341 38.497 1   8.87   ? 533  PHE   A CZ   1 
ATOM   2116 H H    . PHE   A 1 140 ? 24.631 51.217 41.345 1   10.094 ? 533  PHE   A H    1 
ATOM   2117 H HA   . PHE   A 1 140 ? 23.813 53.834 41.782 1   9.86   ? 533  PHE   A HA   1 
ATOM   2118 H HB2  . PHE   A 1 140 ? 22.465 53.679 39.949 1   9.868  ? 533  PHE   A HB2  1 
ATOM   2119 H HB3  . PHE   A 1 140 ? 23.885 53.114 39.552 1   9.841  ? 533  PHE   A HB3  1 
ATOM   2120 H HD1  . PHE   A 1 140 ? 20.596 51.915 40.411 1   9.416  ? 533  PHE   A HD1  1 
ATOM   2121 H HD2  . PHE   A 1 140 ? 24.022 51.006 38.48  1   8.768  ? 533  PHE   A HD2  1 
ATOM   2122 H HE1  . PHE   A 1 140 ? 19.601 49.978 39.533 1   9.297  ? 533  PHE   A HE1  1 
ATOM   2123 H HE2  . PHE   A 1 140 ? 23.027 49.098 37.619 1   8.671  ? 533  PHE   A HE2  1 
ATOM   2124 H HZ   . PHE   A 1 140 ? 20.826 48.569 38.132 1   8.938  ? 533  PHE   A HZ   1 
ATOM   2125 N N    . LYS   A 1 141 ? 22.397 51.456 43.164 1   8.916  ? 534  LYS   A N    1 
ATOM   2126 C CA   . LYS   A 1 141 ? 21.384 51.058 44.13  1   9.749  ? 534  LYS   A CA   1 
ATOM   2127 C C    . LYS   A 1 141 ? 22.009 50.111 45.148 1   9.806  ? 534  LYS   A C    1 
ATOM   2128 O O    . LYS   A 1 141 ? 22.775 49.252 44.77  1   10.125 ? 534  LYS   A O    1 
ATOM   2129 C CB   . LYS   A 1 141 ? 20.159 50.432 43.457 1   9.599  ? 534  LYS   A CB   1 
ATOM   2130 C CG   . LYS   A 1 141 ? 19.06  50.035 44.461 1   9.537  ? 534  LYS   A CG   1 
ATOM   2131 C CD   . LYS   A 1 141 ? 17.676 49.772 43.87  1   10.214 ? 534  LYS   A CD   1 
ATOM   2132 C CE   . LYS   A 1 141 ? 17.002 50.948 43.252 1   10.534 ? 534  LYS   A CE   1 
ATOM   2133 N NZ   . LYS   A 1 141 ? 16.865 52.025 44.245 1   11.136 ? 534  LYS   A NZ   1 
ATOM   2134 H H    . LYS   A 1 141 ? 23.094 50.886 43.007 1   9.192  ? 534  LYS   A H    1 
ATOM   2135 H HA   . LYS   A 1 141 ? 21.084 51.872 44.609 1   9.565  ? 534  LYS   A HA   1 
ATOM   2136 H HB2  . LYS   A 1 141 ? 19.785 51.071 42.814 1   9.63   ? 534  LYS   A HB2  1 
ATOM   2137 H HB3  . LYS   A 1 141 ? 20.438 49.633 42.962 1   9.621  ? 534  LYS   A HB3  1 
ATOM   2138 H HG2  . LYS   A 1 141 ? 19.355 49.225 44.931 1   9.705  ? 534  LYS   A HG2  1 
ATOM   2139 H HG3  . LYS   A 1 141 ? 18.986 50.748 45.131 1   9.716  ? 534  LYS   A HG3  1 
ATOM   2140 H HD2  . LYS   A 1 141 ? 17.76  49.067 43.192 1   10.139 ? 534  LYS   A HD2  1 
ATOM   2141 H HD3  . LYS   A 1 141 ? 17.101 49.419 44.583 1   10.179 ? 534  LYS   A HD3  1 
ATOM   2142 H HE2  . LYS   A 1 141 ? 17.521 51.272 42.494 1   10.59  ? 534  LYS   A HE2  1 
ATOM   2143 H HE3  . LYS   A 1 141 ? 16.118 50.692 42.933 1   10.596 ? 534  LYS   A HE3  1 
ATOM   2144 H HZ1  . LYS   A 1 141 ? 17.634 52.503 44.288 1   10.929 ? 534  LYS   A HZ1  1 
ATOM   2145 H HZ2  . LYS   A 1 141 ? 16.684 51.678 45.062 1   10.933 ? 534  LYS   A HZ2  1 
ATOM   2146 H HZ3  . LYS   A 1 141 ? 16.189 52.577 44.002 1   10.941 ? 534  LYS   A HZ3  1 
ATOM   2147 N N    . TYR   A 1 142 ? 21.648 50.275 46.433 1   10.14  ? 535  TYR   A N    1 
ATOM   2148 C CA   . TYR   A 1 142 ? 22.072 49.417 47.534 1   10.484 ? 535  TYR   A CA   1 
ATOM   2149 C C    . TYR   A 1 142 ? 20.9   48.537 47.967 1   10.404 ? 535  TYR   A C    1 
ATOM   2150 O O    . TYR   A 1 142 ? 19.801 49.037 48.254 1   9.181  ? 535  TYR   A O    1 
ATOM   2151 C CB   . TYR   A 1 142 ? 22.545 50.254 48.73  1   11.138 ? 535  TYR   A CB   1 
ATOM   2152 C CG   . TYR   A 1 142 ? 23.512 51.383 48.397 1   11.287 ? 535  TYR   A CG   1 
ATOM   2153 C CD1  . TYR   A 1 142 ? 24.843 51.146 48.114 1   11.112 ? 535  TYR   A CD1  1 
ATOM   2154 C CD2  . TYR   A 1 142 ? 23.075 52.688 48.366 1   12.943 ? 535  TYR   A CD2  1 
ATOM   2155 C CE1  . TYR   A 1 142 ? 25.706 52.183 47.779 1   11.78  ? 535  TYR   A CE1  1 
ATOM   2156 C CE2  . TYR   A 1 142 ? 23.913 53.741 48     1   15.997 ? 535  TYR   A CE2  1 
ATOM   2157 C CZ   . TYR   A 1 142 ? 25.245 53.485 47.698 1   14.139 ? 535  TYR   A CZ   1 
ATOM   2158 O OH   . TYR   A 1 142 ? 26.075 54.538 47.418 1   13.018 ? 535  TYR   A OH   1 
ATOM   2159 H H    . TYR   A 1 142 ? 21.095 50.975 46.632 1   10.128 ? 535  TYR   A H    1 
ATOM   2160 H HA   . TYR   A 1 142 ? 22.82  48.84  47.227 1   10.512 ? 535  TYR   A HA   1 
ATOM   2161 H HB2  . TYR   A 1 142 ? 21.755 50.638 49.172 1   11.029 ? 535  TYR   A HB2  1 
ATOM   2162 H HB3  . TYR   A 1 142 ? 22.978 49.652 49.375 1   11.022 ? 535  TYR   A HB3  1 
ATOM   2163 H HD1  . TYR   A 1 142 ? 25.169 50.26  48.13  1   11.352 ? 535  TYR   A HD1  1 
ATOM   2164 H HD2  . TYR   A 1 142 ? 22.163 52.869 48.531 1   13.129 ? 535  TYR   A HD2  1 
ATOM   2165 H HE1  . TYR   A 1 142 ? 26.608 51.996 47.583 1   12.13  ? 535  TYR   A HE1  1 
ATOM   2166 H HE2  . TYR   A 1 142 ? 23.586 54.624 47.986 1   14.712 ? 535  TYR   A HE2  1 
ATOM   2167 H HH   . TYR   A 1 142 ? 26.88  54.25  47.308 0   30     ? 535  TYR   A HH   1 
ATOM   2168 N N    . GLN   A 1 143 ? 21.155 47.222 48.016 1   10.739 ? 536  GLN   A N    1 
ATOM   2169 C CA   . GLN   A 1 143 ? 20.088 46.241 48.205 1   10.324 ? 536  GLN   A CA   1 
ATOM   2170 C C    . GLN   A 1 143 ? 20.676 44.973 48.821 1   10.622 ? 536  GLN   A C    1 
ATOM   2171 O O    . GLN   A 1 143 ? 21.761 44.991 49.425 1   10.535 ? 536  GLN   A O    1 
ATOM   2172 C CB   . GLN   A 1 143 ? 19.34  46.03  46.877 1   10.077 ? 536  GLN   A CB   1 
ATOM   2173 C CG   . GLN   A 1 143 ? 20.114 45.325 45.766 1   9.705  ? 536  GLN   A CG   1 
ATOM   2174 C CD   . GLN   A 1 143 ? 19.581 43.948 45.441 1   10.363 ? 536  GLN   A CD   1 
ATOM   2175 O OE1  . GLN   A 1 143 ? 18.368 43.713 45.438 1   10.907 ? 536  GLN   A OE1  1 
ATOM   2176 N NE2  . GLN   A 1 143 ? 20.479 42.991 45.211 1   10.087 ? 536  GLN   A NE2  1 
ATOM   2177 H H    . GLN   A 1 143 ? 22.016 46.926 47.932 1   10.564 ? 536  GLN   A H    1 
ATOM   2178 H HA   . GLN   A 1 143 ? 19.44  46.617 48.855 1   10.405 ? 536  GLN   A HA   1 
ATOM   2179 H HB2  . GLN   A 1 143 ? 18.522 45.525 47.063 1   10.05  ? 536  GLN   A HB2  1 
ATOM   2180 H HB3  . GLN   A 1 143 ? 19.064 46.909 46.545 1   10.08  ? 536  GLN   A HB3  1 
ATOM   2181 H HG2  . GLN   A 1 143 ? 20.08  45.872 44.953 1   9.94   ? 536  GLN   A HG2  1 
ATOM   2182 H HG3  . GLN   A 1 143 ? 21.055 45.243 46.03  1   9.95   ? 536  GLN   A HG3  1 
ATOM   2183 H HE21 . GLN   A 1 143 ? 20.313 42.158 45.465 1   10.17  ? 536  GLN   A HE21 1 
ATOM   2184 H HE22 . GLN   A 1 143 ? 21.243 43.19  44.805 1   10.166 ? 536  GLN   A HE22 1 
ATOM   2185 N N    . GLY   A 1 144 ? 19.958 43.868 48.653 1   10.039 ? 537  GLY   A N    1 
ATOM   2186 C CA   . GLY   A 1 144 ? 20.459 42.59  49.113 1   10.208 ? 537  GLY   A CA   1 
ATOM   2187 C C    . GLY   A 1 144 ? 19.554 41.478 48.627 1   10.062 ? 537  GLY   A C    1 
ATOM   2188 O O    . GLY   A 1 144 ? 18.741 41.689 47.736 1   10.615 ? 537  GLY   A O    1 
ATOM   2189 H H    . GLY   A 1 144 ? 19.131 43.909 48.268 1   10.211 ? 537  GLY   A H    1 
ATOM   2190 H HA2  . GLY   A 1 144 ? 21.373 42.452 48.77  1   10.14  ? 537  GLY   A HA2  1 
ATOM   2191 H HA3  . GLY   A 1 144 ? 20.495 42.587 50.099 1   10.136 ? 537  GLY   A HA3  1 
ATOM   2192 N N    . LEU   A 1 145 ? 19.747 40.282 49.175 1   9.772  ? 538  LEU   A N    1 
ATOM   2193 C CA   . LEU   A 1 145 ? 18.804 39.2   48.939 1   9.909  ? 538  LEU   A CA   1 
ATOM   2194 C C    . LEU   A 1 145 ? 17.73  39.188 50.033 1   10.381 ? 538  LEU   A C    1 
ATOM   2195 O O    . LEU   A 1 145 ? 17.98  39.502 51.204 1   11.262 ? 538  LEU   A O    1 
ATOM   2196 C CB   . LEU   A 1 145 ? 19.535 37.867 48.906 1   9.317  ? 538  LEU   A CB   1 
ATOM   2197 C CG   . LEU   A 1 145 ? 20.502 37.682 47.74  1   9.883  ? 538  LEU   A CG   1 
ATOM   2198 C CD1  . LEU   A 1 145 ? 21.162 36.319 47.845 1   10.785 ? 538  LEU   A CD1  1 
ATOM   2199 C CD2  . LEU   A 1 145 ? 19.746 37.818 46.433 1   10.13  ? 538  LEU   A CD2  1 
ATOM   2200 H H    . LEU   A 1 145 ? 20.476 40.132 49.706 1   9.87   ? 538  LEU   A H    1 
ATOM   2201 H HA   . LEU   A 1 145 ? 18.365 39.352 48.066 1   9.869  ? 538  LEU   A HA   1 
ATOM   2202 H HB2  . LEU   A 1 145 ? 20.039 37.772 49.748 1   9.585  ? 538  LEU   A HB2  1 
ATOM   2203 H HB3  . LEU   A 1 145 ? 18.864 37.147 48.872 1   9.585  ? 538  LEU   A HB3  1 
ATOM   2204 H HG   . LEU   A 1 145 ? 21.199 38.386 47.788 1   9.998  ? 538  LEU   A HG   1 
ATOM   2205 H HD11 . LEU   A 1 145 ? 21.351 36.12  48.777 1   10.579 ? 538  LEU   A HD11 1 
ATOM   2206 H HD12 . LEU   A 1 145 ? 21.993 36.321 47.34  1   10.526 ? 538  LEU   A HD12 1 
ATOM   2207 H HD13 . LEU   A 1 145 ? 20.566 35.641 47.485 1   10.524 ? 538  LEU   A HD13 1 
ATOM   2208 H HD21 . LEU   A 1 145 ? 19.595 38.758 46.24  1   10.062 ? 538  LEU   A HD21 1 
ATOM   2209 H HD22 . LEU   A 1 145 ? 18.892 37.36  46.503 1   10.05  ? 538  LEU   A HD22 1 
ATOM   2210 H HD23 . LEU   A 1 145 ? 20.267 37.42  45.715 1   10.1   ? 538  LEU   A HD23 1 
ATOM   2211 N N    . THR   A 1 146 ? 16.546 38.739 49.627 1   10.828 ? 539  THR   A N    1 
ATOM   2212 C CA   . THR   A 1 146 ? 15.477 38.405 50.55  1   11.64  ? 539  THR   A CA   1 
ATOM   2213 C C    . THR   A 1 146 ? 14.702 37.227 49.972 1   11.752 ? 539  THR   A C    1 
ATOM   2214 O O    . THR   A 1 146 ? 15.153 36.57  49.025 1   12.263 ? 539  THR   A O    1 
ATOM   2215 C CB   . THR   A 1 146 ? 14.609 39.64  50.764 1   11.951 ? 539  THR   A CB   1 
ATOM   2216 O OG1  . THR   A 1 146 ? 13.807 39.445 51.929 1   12.921 ? 539  THR   A OG1  1 
ATOM   2217 C CG2  . THR   A 1 146 ? 13.756 39.97  49.547 1   11.582 ? 539  THR   A CG2  1 
ATOM   2218 H H    . THR   A 1 146 ? 16.394 38.64  48.731 1   10.886 ? 539  THR   A H    1 
ATOM   2219 H HA   . THR   A 1 146 ? 15.871 38.139 51.408 1   11.587 ? 539  THR   A HA   1 
ATOM   2220 H HB   . THR   A 1 146 ? 15.206 40.41  50.923 1   11.998 ? 539  THR   A HB   1 
ATOM   2221 H HG1  . THR   A 1 146 ? 13.3   38.751 51.812 0   30     ? 539  THR   A HG1  1 
ATOM   2222 H HG21 . THR   A 1 146 ? 13.497 40.907 49.578 1   11.656 ? 539  THR   A HG21 1 
ATOM   2223 H HG22 . THR   A 1 146 ? 12.958 39.415 49.548 1   11.681 ? 539  THR   A HG22 1 
ATOM   2224 H HG23 . THR   A 1 146 ? 14.266 39.803 48.736 1   11.677 ? 539  THR   A HG23 1 
ATOM   2225 N N    . ILE   A 1 147 ? 13.551 36.93  50.575 1   12.445 ? 540  ILE   A N    1 
ATOM   2226 C CA   . ILE   A 1 147 ? 12.811 35.73  50.251 1   13.259 ? 540  ILE   A CA   1 
ATOM   2227 C C    . ILE   A 1 147 ? 11.352 36.097 50.011 1   13.048 ? 540  ILE   A C    1 
ATOM   2228 O O    . ILE   A 1 147 ? 10.755 36.789 50.827 1   12.511 ? 540  ILE   A O    1 
ATOM   2229 C CB   . ILE   A 1 147 ? 12.939 34.674 51.368 1   14.81  ? 540  ILE   A CB   1 
ATOM   2230 C CG1  . ILE   A 1 147 ? 14.403 34.373 51.672 1   16.903 ? 540  ILE   A CG1  1 
ATOM   2231 C CG2  . ILE   A 1 147 ? 12.146 33.426 50.988 1   14.711 ? 540  ILE   A CG2  1 
ATOM   2232 C CD1  . ILE   A 1 147 ? 14.622 33.549 52.934 1   19.161 ? 540  ILE   A CD1  1 
ATOM   2233 H H    . ILE   A 1 147 ? 13.219 37.492 51.215 1   12.449 ? 540  ILE   A H    1 
ATOM   2234 H HA   . ILE   A 1 147 ? 13.176 35.352 49.43  1   13.287 ? 540  ILE   A HA   1 
ATOM   2235 H HB   . ILE   A 1 147 ? 12.538 35.048 52.178 1   14.856 ? 540  ILE   A HB   1 
ATOM   2236 H HG12 . ILE   A 1 147 ? 14.789 33.893 50.912 1   16.854 ? 540  ILE   A HG12 1 
ATOM   2237 H HG13 . ILE   A 1 147 ? 14.886 35.219 51.768 1   16.816 ? 540  ILE   A HG13 1 
ATOM   2238 H HG21 . ILE   A 1 147 ? 12.406 32.686 51.559 1   14.781 ? 540  ILE   A HG21 1 
ATOM   2239 H HG22 . ILE   A 1 147 ? 12.326 33.196 50.061 1   14.74  ? 540  ILE   A HG22 1 
ATOM   2240 H HG23 . ILE   A 1 147 ? 11.195 33.597 51.098 1   14.74  ? 540  ILE   A HG23 1 
ATOM   2241 H HD11 . ILE   A 1 147 ? 14.087 33.916 53.662 1   18.485 ? 540  ILE   A HD11 1 
ATOM   2242 H HD12 . ILE   A 1 147 ? 15.566 33.574 53.18  1   18.484 ? 540  ILE   A HD12 1 
ATOM   2243 H HD13 . ILE   A 1 147 ? 14.356 32.624 52.771 1   18.539 ? 540  ILE   A HD13 1 
ATOM   2244 N N    . LEU   A 1 148 ? 10.808 35.631 48.881 1   12.101 ? 541  LEU   A N    1 
ATOM   2245 C CA   . LEU   A 1 148 ? 9.434  35.896 48.49  1   11.98  ? 541  LEU   A CA   1 
ATOM   2246 C C    . LEU   A 1 148 ? 8.649  34.623 48.764 1   12.904 ? 541  LEU   A C    1 
ATOM   2247 O O    . LEU   A 1 148 ? 9.068  33.535 48.342 1   12.114 ? 541  LEU   A O    1 
ATOM   2248 C CB   . LEU   A 1 148 ? 9.351  36.221 47.002 1   12.301 ? 541  LEU   A CB   1 
ATOM   2249 C CG   . LEU   A 1 148 ? 7.967  36.516 46.416 1   13.016 ? 541  LEU   A CG   1 
ATOM   2250 C CD1  . LEU   A 1 148 ? 7.615  37.987 46.637 1   13.977 ? 541  LEU   A CD1  1 
ATOM   2251 C CD2  . LEU   A 1 148 ? 7.941  36.203 44.926 1   14.518 ? 541  LEU   A CD2  1 
ATOM   2252 H H    . LEU   A 1 148 ? 11.323 35.12  48.325 1   12.307 ? 541  LEU   A H    1 
ATOM   2253 H HA   . LEU   A 1 148 ? 9.074  36.647 49.025 1   12.235 ? 541  LEU   A HA   1 
ATOM   2254 H HB2  . LEU   A 1 148 ? 9.93   36.999 46.829 1   12.381 ? 541  LEU   A HB2  1 
ATOM   2255 H HB3  . LEU   A 1 148 ? 9.74   35.465 46.506 1   12.409 ? 541  LEU   A HB3  1 
ATOM   2256 H HG   . LEU   A 1 148 ? 7.294  35.951 46.875 1   13.317 ? 541  LEU   A HG   1 
ATOM   2257 H HD11 . LEU   A 1 148 ? 7.61   38.181 47.589 1   13.671 ? 541  LEU   A HD11 1 
ATOM   2258 H HD12 . LEU   A 1 148 ? 6.736  38.17  46.266 1   13.686 ? 541  LEU   A HD12 1 
ATOM   2259 H HD13 . LEU   A 1 148 ? 8.274  38.549 46.197 1   13.676 ? 541  LEU   A HD13 1 
ATOM   2260 H HD21 . LEU   A 1 148 ? 8.092  35.253 44.791 1   14.048 ? 541  LEU   A HD21 1 
ATOM   2261 H HD22 . LEU   A 1 148 ? 8.639  36.709 44.476 1   14.057 ? 541  LEU   A HD22 1 
ATOM   2262 H HD23 . LEU   A 1 148 ? 7.076  36.448 44.557 1   14.063 ? 541  LEU   A HD23 1 
ATOM   2263 N N    . VAL   A 1 149 ? 7.487  34.789 49.395 1   12.874 ? 542  VAL   A N    1 
ATOM   2264 C CA   . VAL   A 1 149 ? 6.621  33.663 49.714 1   13.706 ? 542  VAL   A CA   1 
ATOM   2265 C C    . VAL   A 1 149 ? 5.187  34.116 49.524 1   13.876 ? 542  VAL   A C    1 
ATOM   2266 O O    . VAL   A 1 149 ? 4.917  35.318 49.421 1   13.722 ? 542  VAL   A O    1 
ATOM   2267 C CB   . VAL   A 1 149 ? 6.801  33.131 51.147 1   14.234 ? 542  VAL   A CB   1 
ATOM   2268 C CG1  . VAL   A 1 149 ? 8.199  32.575 51.389 1   15.141 ? 542  VAL   A CG1  1 
ATOM   2269 C CG2  . VAL   A 1 149 ? 6.468  34.201 52.181 1   12.898 ? 542  VAL   A CG2  1 
ATOM   2270 H H    . VAL   A 1 149 ? 7.223  35.63  49.637 1   13.055 ? 542  VAL   A H    1 
ATOM   2271 H HA   . VAL   A 1 149 ? 6.804  32.937 49.086 1   13.673 ? 542  VAL   A HA   1 
ATOM   2272 H HB   . VAL   A 1 149 ? 6.161  32.39  51.264 1   14.112 ? 542  VAL   A HB   1 
ATOM   2273 H HG11 . VAL   A 1 149 ? 8.842  33.304 51.39  1   14.859 ? 542  VAL   A HG11 1 
ATOM   2274 H HG12 . VAL   A 1 149 ? 8.425  31.946 50.684 1   14.868 ? 542  VAL   A HG12 1 
ATOM   2275 H HG13 . VAL   A 1 149 ? 8.224  32.121 52.248 1   14.866 ? 542  VAL   A HG13 1 
ATOM   2276 H HG21 . VAL   A 1 149 ? 6.814  33.933 53.049 1   13.292 ? 542  VAL   A HG21 1 
ATOM   2277 H HG22 . VAL   A 1 149 ? 5.504  34.311 52.239 1   13.296 ? 542  VAL   A HG22 1 
ATOM   2278 H HG23 . VAL   A 1 149 ? 6.874  35.045 51.92  1   13.281 ? 542  VAL   A HG23 1 
ATOM   2279 N N    . LYS   A 1 150 ? 4.276  33.137 49.529 1   14.16  ? 543  LYS   A N    1 
ATOM   2280 C CA   . LYS   A 1 150 ? 2.854  33.429 49.561 1   17.481 ? 543  LYS   A CA   1 
ATOM   2281 C C    . LYS   A 1 150 ? 2.473  33.996 50.928 1   15.788 ? 543  LYS   A C    1 
ATOM   2282 O O    . LYS   A 1 150 ? 3.003  33.6   51.976 1   15.895 ? 543  LYS   A O    1 
ATOM   2283 C CB   . LYS   A 1 150 ? 2.105  32.135 49.198 1   21.778 ? 543  LYS   A CB   1 
ATOM   2284 C CG   . LYS   A 1 150 ? 0.656  32.302 48.814 1   24.751 ? 543  LYS   A CG   1 
ATOM   2285 C CD   . LYS   A 1 150 ? 0.446  32.835 47.398 1   28.838 ? 543  LYS   A CD   1 
ATOM   2286 C CE   . LYS   A 1 150 ? -0.904 32.49  46.835 1   30.611 ? 543  LYS   A CE   1 
ATOM   2287 N NZ   . LYS   A 1 150 ? -1.188 33.227 45.59  1   31.93  ? 543  LYS   A NZ   1 
ATOM   2288 H H    . LYS   A 1 150 ? 4.55   32.265 49.514 1   14.842 ? 543  LYS   A H    1 
ATOM   2289 H HA   . LYS   A 1 150 ? 2.662  34.111 48.868 1   17.104 ? 543  LYS   A HA   1 
ATOM   2290 H HB2  . LYS   A 1 150 ? 2.573  31.703 48.451 1   21.282 ? 543  LYS   A HB2  1 
ATOM   2291 H HB3  . LYS   A 1 150 ? 2.15   31.525 49.965 1   21.335 ? 543  LYS   A HB3  1 
ATOM   2292 H HG2  . LYS   A 1 150 ? 0.21   31.432 48.897 1   24.894 ? 543  LYS   A HG2  1 
ATOM   2293 H HG3  . LYS   A 1 150 ? 0.233  32.917 49.452 1   24.83  ? 543  LYS   A HG3  1 
ATOM   2294 H HD2  . LYS   A 1 150 ? 0.549  33.811 47.408 1   28.168 ? 543  LYS   A HD2  1 
ATOM   2295 H HD3  . LYS   A 1 150 ? 1.14   32.465 46.81  1   28.138 ? 543  LYS   A HD3  1 
ATOM   2296 H HE2  . LYS   A 1 150 ? -0.944 31.534 46.653 1   30.498 ? 543  LYS   A HE2  1 
ATOM   2297 H HE3  . LYS   A 1 150 ? -1.592 32.702 47.491 1   30.498 ? 543  LYS   A HE3  1 
ATOM   2298 H HZ1  . LYS   A 1 150 ? -0.891 32.75  44.88  1   31.382 ? 543  LYS   A HZ1  1 
ATOM   2299 H HZ2  . LYS   A 1 150 ? -0.777 34.033 45.598 1   31.241 ? 543  LYS   A HZ2  1 
ATOM   2300 H HZ3  . LYS   A 1 150 ? -2.082 33.352 45.508 1   31.439 ? 543  LYS   A HZ3  1 
ATOM   2301 N N    . LYS   A 1 151 ? 1.566  34.978 50.926 1   17.45  ? 544  LYS   A N    1 
ATOM   2302 C CA   . LYS   A 1 151 ? 1.034  35.543 52.157 1   19.804 ? 544  LYS   A CA   1 
ATOM   2303 C C    . LYS   A 1 151 ? 0.512  34.397 53.022 1   20.73  ? 544  LYS   A C    1 
ATOM   2304 O O    . LYS   A 1 151 ? -0.169 33.518 52.49  1   19.998 ? 544  LYS   A O    1 
ATOM   2305 C CB   . LYS   A 1 151 ? -0.08  36.528 51.792 1   21.511 ? 544  LYS   A CB   1 
ATOM   2306 C CG   . LYS   A 1 151 ? -0.973 36.992 52.929 1   25.344 ? 544  LYS   A CG   1 
ATOM   2307 C CD   . LYS   A 1 151 ? -1.958 38.083 52.522 1   27.855 ? 544  LYS   A CD   1 
ATOM   2308 C CE   . LYS   A 1 151 ? -2.795 37.821 51.315 1   32.5   ? 544  LYS   A CE   1 
ATOM   2309 N NZ   . LYS   A 1 151 ? -3.467 39.057 50.848 1   38.718 ? 544  LYS   A NZ   1 
ATOM   2310 H H    . LYS   A 1 151 ? 1.269  35.309 50.127 1   17.585 ? 544  LYS   A H    1 
ATOM   2311 H HA   . LYS   A 1 151 ? 1.764  36.014 52.634 1   19.842 ? 544  LYS   A HA   1 
ATOM   2312 H HB2  . LYS   A 1 151 ? 0.329  37.32  51.383 1   21.934 ? 544  LYS   A HB2  1 
ATOM   2313 H HB3  . LYS   A 1 151 ? -0.647 36.106 51.112 1   21.97  ? 544  LYS   A HB3  1 
ATOM   2314 H HG2  . LYS   A 1 151 ? -1.476 36.22  53.268 1   24.914 ? 544  LYS   A HG2  1 
ATOM   2315 H HG3  . LYS   A 1 151 ? -0.406 37.327 53.657 1   24.931 ? 544  LYS   A HG3  1 
ATOM   2316 H HD2  . LYS   A 1 151 ? -2.556 38.252 53.283 1   28.272 ? 544  LYS   A HD2  1 
ATOM   2317 H HD3  . LYS   A 1 151 ? -1.45  38.91  52.372 1   28.31  ? 544  LYS   A HD3  1 
ATOM   2318 H HE2  . LYS   A 1 151 ? -2.245 37.475 50.592 1   32.359 ? 544  LYS   A HE2  1 
ATOM   2319 H HE3  . LYS   A 1 151 ? -3.472 37.153 51.528 1   32.615 ? 544  LYS   A HE3  1 
ATOM   2320 H HZ1  . LYS   A 1 151 ? -2.847 39.656 50.57  1   36.608 ? 544  LYS   A HZ1  1 
ATOM   2321 H HZ2  . LYS   A 1 151 ? -3.949 39.419 51.525 1   36.612 ? 544  LYS   A HZ2  1 
ATOM   2322 H HZ3  . LYS   A 1 151 ? -4.023 38.862 50.159 1   36.657 ? 544  LYS   A HZ3  1 
ATOM   2323 N N    . GLY   A 1 152 ? 0.888  34.401 54.309 1   26.312 ? 545  GLY   A N    1 
ATOM   2324 C CA   . GLY   A 1 152 ? 0.499  33.349 55.231 1   29.606 ? 545  GLY   A CA   1 
ATOM   2325 C C    . GLY   A 1 152 ? 1.636  32.371 55.516 1   30.167 ? 545  GLY   A C    1 
ATOM   2326 O O    . GLY   A 1 152 ? 1.62   31.716 56.555 1   30.573 ? 545  GLY   A O    1 
ATOM   2327 H H    . GLY   A 1 152 ? 1.404  35.087 54.622 1   25.427 ? 545  GLY   A H    1 
ATOM   2328 H HA2  . GLY   A 1 152 ? 0.206  33.761 56.077 1   28.879 ? 545  GLY   A HA2  1 
ATOM   2329 H HA3  . GLY   A 1 152 ? -0.269 32.857 54.856 1   28.783 ? 545  GLY   A HA3  1 
ATOM   2330 N N    . THR   A 1 153 ? 2.634  32.294 54.615 1   29.085 ? 546  THR   A N    1 
ATOM   2331 C CA   . THR   A 1 153 ? 3.695  31.303 54.708 1   28.196 ? 546  THR   A CA   1 
ATOM   2332 C C    . THR   A 1 153 ? 4.582  31.613 55.916 1   30.308 ? 546  THR   A C    1 
ATOM   2333 O O    . THR   A 1 153 ? 5.093  32.729 56.06  1   27.18  ? 546  THR   A O    1 
ATOM   2334 C CB   . THR   A 1 153 ? 4.507  31.253 53.412 1   28.324 ? 546  THR   A CB   1 
ATOM   2335 O OG1  . THR   A 1 153 ? 3.719  30.666 52.382 1   29.719 ? 546  THR   A OG1  1 
ATOM   2336 C CG2  . THR   A 1 153 ? 5.729  30.364 53.507 1   28.645 ? 546  THR   A CG2  1 
ATOM   2337 H H    . THR   A 1 153 ? 2.652  32.884 53.919 1   29.047 ? 546  THR   A H    1 
ATOM   2338 H HA   . THR   A 1 153 ? 3.278  30.424 54.842 1   28.812 ? 546  THR   A HA   1 
ATOM   2339 H HB   . THR   A 1 153 ? 4.779  32.163 53.147 1   28.287 ? 546  THR   A HB   1 
ATOM   2340 H HG1  . THR   A 1 153 ? 3.496  29.89  52.601 0   30     ? 546  THR   A HG1  1 
ATOM   2341 H HG21 . THR   A 1 153 ? 6.005  30.093 52.615 1   28.577 ? 546  THR   A HG21 1 
ATOM   2342 H HG22 . THR   A 1 153 ? 5.517  29.575 54.033 1   28.577 ? 546  THR   A HG22 1 
ATOM   2343 H HG23 . THR   A 1 153 ? 6.454  30.851 53.934 1   28.626 ? 546  THR   A HG23 1 
ATOM   2344 N N    . ARG   A 1 154 ? 4.781  30.582 56.757 1   30.441 ? 663  ARG   A N    1 
ATOM   2345 C CA   . ARG   A 1 154 ? 5.48   30.695 58.026 1   35.513 ? 663  ARG   A CA   1 
ATOM   2346 C C    . ARG   A 1 154 ? 6.971  30.415 57.836 1   36.957 ? 663  ARG   A C    1 
ATOM   2347 O O    . ARG   A 1 154 ? 7.422  29.291 58.057 1   40.836 ? 663  ARG   A O    1 
ATOM   2348 C CB   . ARG   A 1 154 ? 4.922  29.699 59.055 1   38.027 ? 663  ARG   A CB   1 
ATOM   2349 H H    . ARG   A 1 154 ? 4.465  29.759 56.514 1   31.482 ? 663  ARG   A H    1 
ATOM   2350 H HA   . ARG   A 1 154 ? 5.365  31.617 58.371 1   35.071 ? 663  ARG   A HA   1 
ATOM   2351 H HB2  . ARG   A 1 154 ? 5.693  29.274 59.517 0   30     ? 663  ARG   A HB2  1 
ATOM   2352 H HB3  . ARG   A 1 154 ? 3.958  29.734 59.037 0   30     ? 663  ARG   A HB3  1 
ATOM   2353 N N    . ILE   A 1 155 ? 7.708  31.45  57.421 1   35.698 ? 664  ILE   A N    1 
ATOM   2354 C CA   . ILE   A 1 155 ? 9.148  31.393 57.19  1   37.119 ? 664  ILE   A CA   1 
ATOM   2355 C C    . ILE   A 1 155 ? 9.742  32.687 57.732 1   34.347 ? 664  ILE   A C    1 
ATOM   2356 O O    . ILE   A 1 155 ? 9.249  33.755 57.389 1   38.738 ? 664  ILE   A O    1 
ATOM   2357 C CB   . ILE   A 1 155 ? 9.487  31.233 55.689 1   37.003 ? 664  ILE   A CB   1 
ATOM   2358 C CG1  . ILE   A 1 155 ? 9.03   29.886 55.145 1   40.209 ? 664  ILE   A CG1  1 
ATOM   2359 C CG2  . ILE   A 1 155 ? 10.978 31.466 55.406 1   34.526 ? 664  ILE   A CG2  1 
ATOM   2360 C CD1  . ILE   A 1 155 ? 9.782  28.7   55.729 1   42.023 ? 664  ILE   A CD1  1 
ATOM   2361 H H    . ILE   A 1 155 ? 7.283  32.245 57.268 1   36.284 ? 664  ILE   A H    1 
ATOM   2362 H HA   . ILE   A 1 155 ? 9.52   30.64  57.684 1   36.339 ? 664  ILE   A HA   1 
ATOM   2363 H HB   . ILE   A 1 155 ? 8.988  31.922 55.206 1   37.128 ? 664  ILE   A HB   1 
ATOM   2364 H HG12 . ILE   A 1 155 ? 8.076  29.777 55.33  1   39.748 ? 664  ILE   A HG12 1 
ATOM   2365 H HG13 . ILE   A 1 155 ? 9.149  29.886 54.174 1   39.913 ? 664  ILE   A HG13 1 
ATOM   2366 H HG21 . ILE   A 1 155 ? 11.227 31.02  54.578 1   35.258 ? 664  ILE   A HG21 1 
ATOM   2367 H HG22 . ILE   A 1 155 ? 11.51  31.107 56.136 1   35.234 ? 664  ILE   A HG22 1 
ATOM   2368 H HG23 . ILE   A 1 155 ? 11.15  32.419 55.321 1   35.233 ? 664  ILE   A HG23 1 
ATOM   2369 H HD11 . ILE   A 1 155 ? 10.729 28.763 55.5   1   41.437 ? 664  ILE   A HD11 1 
ATOM   2370 H HD12 . ILE   A 1 155 ? 9.416  27.875 55.357 1   41.505 ? 664  ILE   A HD12 1 
ATOM   2371 H HD13 . ILE   A 1 155 ? 9.685  28.686 56.699 1   41.415 ? 664  ILE   A HD13 1 
ATOM   2372 N N    . THR   A 1 156 ? 10.833 32.589 58.502 1   33.272 ? 665  THR   A N    1 
ATOM   2373 C CA   . THR   A 1 156 ? 11.37  33.749 59.204 1   36.389 ? 665  THR   A CA   1 
ATOM   2374 C C    . THR   A 1 156 ? 12.491 34.427 58.423 1   33.62  ? 665  THR   A C    1 
ATOM   2375 O O    . THR   A 1 156 ? 12.758 35.604 58.657 1   30.091 ? 665  THR   A O    1 
ATOM   2376 C CB   . THR   A 1 156 ? 11.887 33.383 60.594 1   39.603 ? 665  THR   A CB   1 
ATOM   2377 O OG1  . THR   A 1 156 ? 12.879 32.373 60.43  1   37.013 ? 665  THR   A OG1  1 
ATOM   2378 C CG2  . THR   A 1 156 ? 10.761 32.952 61.512 1   39.359 ? 665  THR   A CG2  1 
ATOM   2379 H H    . THR   A 1 156 ? 11.253 31.783 58.593 1   34.21  ? 665  THR   A H    1 
ATOM   2380 H HA   . THR   A 1 156 ? 10.642 34.398 59.316 1   35.807 ? 665  THR   A HA   1 
ATOM   2381 H HB   . THR   A 1 156 ? 12.311 34.181 60.992 1   38.416 ? 665  THR   A HB   1 
ATOM   2382 H HG1  . THR   A 1 156 ? 12.545 31.67  60.048 0   30     ? 665  THR   A HG1  1 
ATOM   2383 H HG21 . THR   A 1 156 ? 11.121 32.756 62.391 1   39.428 ? 665  THR   A HG21 1 
ATOM   2384 H HG22 . THR   A 1 156 ? 10.334 32.157 61.152 1   39.423 ? 665  THR   A HG22 1 
ATOM   2385 H HG23 . THR   A 1 156 ? 10.106 33.667 61.582 1   39.429 ? 665  THR   A HG23 1 
ATOM   2386 N N    . GLY   A 1 157 ? 13.195 33.678 57.572 1   28.069 ? 666  GLY   A N    1 
ATOM   2387 C CA   . GLY   A 1 157 ? 14.447 34.184 57.028 1   28.598 ? 666  GLY   A CA   1 
ATOM   2388 C C    . GLY   A 1 157 ? 15.257 33.048 56.436 1   26.886 ? 666  GLY   A C    1 
ATOM   2389 O O    . GLY   A 1 157 ? 14.766 31.921 56.33  1   23.746 ? 666  GLY   A O    1 
ATOM   2390 H H    . GLY   A 1 157 ? 12.899 32.85  57.324 1   29.514 ? 666  GLY   A H    1 
ATOM   2391 H HA2  . GLY   A 1 157 ? 14.253 34.852 56.332 1   28.119 ? 666  GLY   A HA2  1 
ATOM   2392 H HA3  . GLY   A 1 157 ? 14.963 34.623 57.744 1   28.126 ? 666  GLY   A HA3  1 
ATOM   2393 N N    . ILE   A 1 158 ? 16.505 33.365 56.098 1   26.472 ? 667  ILE   A N    1 
ATOM   2394 C CA   . ILE   A 1 158 ? 17.363 32.416 55.412 1   27.5   ? 667  ILE   A CA   1 
ATOM   2395 C C    . ILE   A 1 158 ? 17.789 31.318 56.39  1   29.337 ? 667  ILE   A C    1 
ATOM   2396 O O    . ILE   A 1 158 ? 18.177 30.234 55.947 1   28.684 ? 667  ILE   A O    1 
ATOM   2397 C CB   . ILE   A 1 158 ? 18.566 33.126 54.752 1   28.18  ? 667  ILE   A CB   1 
ATOM   2398 C CG1  . ILE   A 1 158 ? 19.293 32.23  53.761 1   27.385 ? 667  ILE   A CG1  1 
ATOM   2399 C CG2  . ILE   A 1 158 ? 19.529 33.696 55.79  1   28.167 ? 667  ILE   A CG2  1 
ATOM   2400 C CD1  . ILE   A 1 158 ? 18.458 31.763 52.587 1   27.375 ? 667  ILE   A CD1  1 
ATOM   2401 H H    . ILE   A 1 158 ? 16.829 34.196 56.296 1   26.839 ? 667  ILE   A H    1 
ATOM   2402 H HA   . ILE   A 1 158 ? 16.837 32.002 54.704 1   27.781 ? 667  ILE   A HA   1 
ATOM   2403 H HB   . ILE   A 1 158 ? 18.208 33.882 54.244 1   27.831 ? 667  ILE   A HB   1 
ATOM   2404 H HG12 . ILE   A 1 158 ? 20.068 32.719 53.415 1   27.565 ? 667  ILE   A HG12 1 
ATOM   2405 H HG13 . ILE   A 1 158 ? 19.63  31.445 54.237 1   27.576 ? 667  ILE   A HG13 1 
ATOM   2406 H HG21 . ILE   A 1 158 ? 20.129 34.33  55.363 1   28.167 ? 667  ILE   A HG21 1 
ATOM   2407 H HG22 . ILE   A 1 158 ? 20.05  32.976 56.183 1   28.171 ? 667  ILE   A HG22 1 
ATOM   2408 H HG23 . ILE   A 1 158 ? 19.028 34.149 56.489 1   28.152 ? 667  ILE   A HG23 1 
ATOM   2409 H HD11 . ILE   A 1 158 ? 17.794 31.117 52.892 1   27.466 ? 667  ILE   A HD11 1 
ATOM   2410 H HD12 . ILE   A 1 158 ? 19.037 31.342 51.925 1   27.418 ? 667  ILE   A HD12 1 
ATOM   2411 H HD13 . ILE   A 1 158 ? 18.005 32.527 52.183 1   27.33  ? 667  ILE   A HD13 1 
ATOM   2412 N N    . ASN   A 1 159 ? 17.717 31.615 57.701 1   27.852 ? 668  ASN   A N    1 
ATOM   2413 C CA   . ASN   A 1 159 ? 18.149 30.679 58.735 1   34.02  ? 668  ASN   A CA   1 
ATOM   2414 C C    . ASN   A 1 159 ? 16.985 29.844 59.265 1   33.023 ? 668  ASN   A C    1 
ATOM   2415 O O    . ASN   A 1 159 ? 17.174 29.081 60.21  1   32.943 ? 668  ASN   A O    1 
ATOM   2416 C CB   . ASN   A 1 159 ? 18.82  31.399 59.901 1   35.309 ? 668  ASN   A CB   1 
ATOM   2417 C CG   . ASN   A 1 159 ? 20.052 32.136 59.434 1   38.42  ? 668  ASN   A CG   1 
ATOM   2418 O OD1  . ASN   A 1 159 ? 20.153 33.354 59.612 1   42.62  ? 668  ASN   A OD1  1 
ATOM   2419 N ND2  . ASN   A 1 159 ? 20.984 31.424 58.818 1   38.118 ? 668  ASN   A ND2  1 
ATOM   2420 H H    . ASN   A 1 159 ? 17.406 32.434 57.96  1   29.445 ? 668  ASN   A H    1 
ATOM   2421 H HA   . ASN   A 1 159 ? 18.812 30.069 58.343 1   32.968 ? 668  ASN   A HA   1 
ATOM   2422 H HB2  . ASN   A 1 159 ? 18.191 32.034 60.297 1   35.731 ? 668  ASN   A HB2  1 
ATOM   2423 H HB3  . ASN   A 1 159 ? 19.072 30.748 60.586 1   35.676 ? 668  ASN   A HB3  1 
ATOM   2424 H HD21 . ASN   A 1 159 ? 21.554 31.826 58.272 1   38.393 ? 668  ASN   A HD21 1 
ATOM   2425 H HD22 . ASN   A 1 159 ? 21.039 30.549 58.955 1   38.19  ? 668  ASN   A HD22 1 
ATOM   2426 N N    . ASP   A 1 160 ? 15.795 29.986 58.666 1   30.391 ? 669  ASP   A N    1 
ATOM   2427 C CA   . ASP   A 1 160 ? 14.656 29.161 59.039 1   31.69  ? 669  ASP   A CA   1 
ATOM   2428 C C    . ASP   A 1 160 ? 15.018 27.69  58.825 1   30.019 ? 669  ASP   A C    1 
ATOM   2429 O O    . ASP   A 1 160 ? 15.562 27.327 57.79  1   27.989 ? 669  ASP   A O    1 
ATOM   2430 C CB   . ASP   A 1 160 ? 13.399 29.563 58.287 1   33.804 ? 669  ASP   A CB   1 
ATOM   2431 C CG   . ASP   A 1 160 ? 12.092 29.063 58.89  1   35.804 ? 669  ASP   A CG   1 
ATOM   2432 O OD1  . ASP   A 1 160 ? 11.871 27.841 58.856 1   37.013 ? 669  ASP   A OD1  1 
ATOM   2433 O OD2  . ASP   A 1 160 ? 11.306 29.905 59.371 1   35.053 ? 669  ASP   A OD2  1 
ATOM   2434 H H    . ASP   A 1 160 ? 15.686 30.615 58.012 1   31.279 ? 669  ASP   A H    1 
ATOM   2435 H HA   . ASP   A 1 160 ? 14.479 29.308 59.993 1   31.484 ? 669  ASP   A HA   1 
ATOM   2436 H HB2  . ASP   A 1 160 ? 13.359 30.542 58.244 1   33.738 ? 669  ASP   A HB2  1 
ATOM   2437 H HB3  . ASP   A 1 160 ? 13.46  29.225 57.37  1   33.728 ? 669  ASP   A HB3  1 
ATOM   2438 N N    . PRO   A 1 161 ? 14.751 26.78  59.799 1   29.09  ? 670  PRO   A N    1 
ATOM   2439 C CA   . PRO   A 1 161 ? 14.992 25.354 59.608 1   27.57  ? 670  PRO   A CA   1 
ATOM   2440 C C    . PRO   A 1 161 ? 14.411 24.701 58.359 1   31.453 ? 670  PRO   A C    1 
ATOM   2441 O O    . PRO   A 1 161 ? 15.026 23.775 57.82  1   35.569 ? 670  PRO   A O    1 
ATOM   2442 C CB   . PRO   A 1 161 ? 14.442 24.746 60.891 1   29.52  ? 670  PRO   A CB   1 
ATOM   2443 C CG   . PRO   A 1 161 ? 14.757 25.828 61.917 1   27.56  ? 670  PRO   A CG   1 
ATOM   2444 C CD   . PRO   A 1 161 ? 14.412 27.1   61.194 1   29.161 ? 670  PRO   A CD   1 
ATOM   2445 H HA   . PRO   A 1 161 ? 15.961 25.208 59.603 1   29.033 ? 670  PRO   A HA   1 
ATOM   2446 H HB2  . PRO   A 1 161 ? 13.48  24.59  60.824 1   28.639 ? 670  PRO   A HB2  1 
ATOM   2447 H HB3  . PRO   A 1 161 ? 14.897 23.909 61.108 1   28.627 ? 670  PRO   A HB3  1 
ATOM   2448 H HG2  . PRO   A 1 161 ? 14.21  25.724 62.721 1   28.35  ? 670  PRO   A HG2  1 
ATOM   2449 H HG3  . PRO   A 1 161 ? 15.703 25.814 62.167 1   28.35  ? 670  PRO   A HG3  1 
ATOM   2450 H HD2  . PRO   A 1 161 ? 13.463 27.314 61.28  1   28.783 ? 670  PRO   A HD2  1 
ATOM   2451 H HD3  . PRO   A 1 161 ? 14.946 27.849 61.521 1   28.809 ? 670  PRO   A HD3  1 
ATOM   2452 N N    . ARG   A 1 162 ? 13.244 25.159 57.893 1   33.209 ? 671  ARG   A N    1 
ATOM   2453 C CA   . ARG   A 1 162 ? 12.673 24.642 56.654 1   38.742 ? 671  ARG   A CA   1 
ATOM   2454 C C    . ARG   A 1 162 ? 13.597 24.849 55.451 1   37.611 ? 671  ARG   A C    1 
ATOM   2455 O O    . ARG   A 1 162 ? 13.556 24.075 54.49  1   35.508 ? 671  ARG   A O    1 
ATOM   2456 C CB   . ARG   A 1 162 ? 11.29  25.245 56.374 1   41.205 ? 671  ARG   A CB   1 
ATOM   2457 C CG   . ARG   A 1 162 ? 10.247 24.503 57.195 1   45.762 ? 671  ARG   A CG   1 
ATOM   2458 C CD   . ARG   A 1 162 ? 8.842  24.482 56.629 1   46.593 ? 671  ARG   A CD   1 
ATOM   2459 N NE   . ARG   A 1 162 ? 8.075  25.709 56.865 1   46.648 ? 671  ARG   A NE   1 
ATOM   2460 C CZ   . ARG   A 1 162 ? 6.868  25.908 56.341 1   47.599 ? 671  ARG   A CZ   1 
ATOM   2461 N NH1  . ARG   A 1 162 ? 6.307  24.945 55.625 1   47.878 ? 671  ARG   A NH1  1 
ATOM   2462 N NH2  . ARG   A 1 162 ? 6.232  27.052 56.533 1   46.79  ? 671  ARG   A NH2  1 
ATOM   2463 H H    . ARG   A 1 162 ? 12.791 25.803 58.357 1   33.955 ? 671  ARG   A H    1 
ATOM   2464 H HA   . ARG   A 1 162 ? 12.554 23.665 56.769 1   37.896 ? 671  ARG   A HA   1 
ATOM   2465 H HB2  . ARG   A 1 162 ? 11.284 26.196 56.615 1   41.567 ? 671  ARG   A HB2  1 
ATOM   2466 H HB3  . ARG   A 1 162 ? 11.076 25.164 55.42  1   41.619 ? 671  ARG   A HB3  1 
ATOM   2467 H HG2  . ARG   A 1 162 ? 10.543 23.575 57.316 1   44.764 ? 671  ARG   A HG2  1 
ATOM   2468 H HG3  . ARG   A 1 162 ? 10.214 24.906 58.09  1   44.844 ? 671  ARG   A HG3  1 
ATOM   2469 H HD2  . ARG   A 1 162 ? 8.899  24.323 55.665 1   46.39  ? 671  ARG   A HD2  1 
ATOM   2470 H HD3  . ARG   A 1 162 ? 8.36   23.727 57.024 1   46.411 ? 671  ARG   A HD3  1 
ATOM   2471 H HE   . ARG   A 1 162 ? 8.424  26.331 57.367 1   46.853 ? 671  ARG   A HE   1 
ATOM   2472 H HH11 . ARG   A 1 162 ? 6.204  24.139 55.972 1   47.79  ? 671  ARG   A HH11 1 
ATOM   2473 H HH12 . ARG   A 1 162 ? 6.026  25.118 54.806 1   47.813 ? 671  ARG   A HH12 1 
ATOM   2474 H HH21 . ARG   A 1 162 ? 6.495  27.601 57.174 1   46.974 ? 671  ARG   A HH21 1 
ATOM   2475 H HH22 . ARG   A 1 162 ? 5.545  27.263 56.018 1   47.029 ? 671  ARG   A HH22 1 
ATOM   2476 N N    . LEU   A 1 163 ? 14.418 25.91  55.485 1   39.201 ? 672  LEU   A N    1 
ATOM   2477 C CA   . LEU   A 1 163 ? 15.386 26.151 54.424 1   40.729 ? 672  LEU   A CA   1 
ATOM   2478 C C    . LEU   A 1 163 ? 16.683 25.377 54.692 1   45.981 ? 672  LEU   A C    1 
ATOM   2479 O O    . LEU   A 1 163 ? 17.218 24.741 53.783 1   45.276 ? 672  LEU   A O    1 
ATOM   2480 C CB   . LEU   A 1 163 ? 15.651 27.647 54.289 1   39.475 ? 672  LEU   A CB   1 
ATOM   2481 C CG   . LEU   A 1 163 ? 14.432 28.565 54.162 1   37.943 ? 672  LEU   A CG   1 
ATOM   2482 C CD1  . LEU   A 1 163 ? 14.961 29.941 53.809 1   37.648 ? 672  LEU   A CD1  1 
ATOM   2483 C CD2  . LEU   A 1 163 ? 13.402 28.132 53.146 1   36.691 ? 672  LEU   A CD2  1 
ATOM   2484 H H    . LEU   A 1 163 ? 14.366 26.503 56.178 1   39.053 ? 672  LEU   A H    1 
ATOM   2485 H HA   . LEU   A 1 163 ? 15.001 25.82  53.573 1   41.022 ? 672  LEU   A HA   1 
ATOM   2486 H HB2  . LEU   A 1 163 ? 16.173 27.935 55.072 1   39.435 ? 672  LEU   A HB2  1 
ATOM   2487 H HB3  . LEU   A 1 163 ? 16.22  27.782 53.497 1   39.472 ? 672  LEU   A HB3  1 
ATOM   2488 H HG   . LEU   A 1 163 ? 13.99  28.62  55.048 1   37.925 ? 672  LEU   A HG   1 
ATOM   2489 H HD11 . LEU   A 1 163 ? 15.663 30.187 54.433 1   37.521 ? 672  LEU   A HD11 1 
ATOM   2490 H HD12 . LEU   A 1 163 ? 14.239 30.589 53.861 1   37.487 ? 672  LEU   A HD12 1 
ATOM   2491 H HD13 . LEU   A 1 163 ? 15.32  29.929 52.906 1   37.646 ? 672  LEU   A HD13 1 
ATOM   2492 H HD21 . LEU   A 1 163 ? 12.967 27.317 53.45  1   37.075 ? 672  LEU   A HD21 1 
ATOM   2493 H HD22 . LEU   A 1 163 ? 13.837 27.966 52.293 1   37.063 ? 672  LEU   A HD22 1 
ATOM   2494 H HD23 . LEU   A 1 163 ? 12.737 28.832 53.039 1   37.063 ? 672  LEU   A HD23 1 
ATOM   2495 N N    . ARG   A 1 164 ? 17.17  25.431 55.948 1   50     ? 673  ARG   A N    1 
ATOM   2496 C CA   . ARG   A 1 164 ? 18.435 24.83  56.365 1   49.072 ? 673  ARG   A CA   1 
ATOM   2497 C C    . ARG   A 1 164 ? 18.404 23.308 56.288 1   51.359 ? 673  ARG   A C    1 
ATOM   2498 O O    . ARG   A 1 164 ? 19.392 22.698 55.883 1   55.597 ? 673  ARG   A O    1 
ATOM   2499 C CB   . ARG   A 1 164 ? 18.738 25.197 57.821 1   54.326 ? 673  ARG   A CB   1 
ATOM   2500 C CG   . ARG   A 1 164 ? 19.154 26.649 57.961 1   60.552 ? 673  ARG   A CG   1 
ATOM   2501 C CD   . ARG   A 1 164 ? 20.6   26.804 57.552 1   63.073 ? 673  ARG   A CD   1 
ATOM   2502 N NE   . ARG   A 1 164 ? 20.874 28.184 57.158 1   65.277 ? 673  ARG   A NE   1 
ATOM   2503 C CZ   . ARG   A 1 164 ? 22.075 28.63  56.829 1   69.637 ? 673  ARG   A CZ   1 
ATOM   2504 N NH1  . ARG   A 1 164 ? 23.11  27.802 56.774 1   68.252 ? 673  ARG   A NH1  1 
ATOM   2505 N NH2  . ARG   A 1 164 ? 22.22  29.914 56.55  1   72.365 ? 673  ARG   A NH2  1 
ATOM   2506 H H    . ARG   A 1 164 ? 16.681 25.877 56.578 1   48.748 ? 673  ARG   A H    1 
ATOM   2507 H HA   . ARG   A 1 164 ? 19.154 25.167 55.774 1   50.713 ? 673  ARG   A HA   1 
ATOM   2508 H HB2  . ARG   A 1 164 ? 17.94  25.036 58.369 1   54.152 ? 673  ARG   A HB2  1 
ATOM   2509 H HB3  . ARG   A 1 164 ? 19.458 24.622 58.158 1   54.404 ? 673  ARG   A HB3  1 
ATOM   2510 H HG2  . ARG   A 1 164 ? 18.59  27.211 57.387 1   59.587 ? 673  ARG   A HG2  1 
ATOM   2511 H HG3  . ARG   A 1 164 ? 19.046 26.938 58.891 1   59.624 ? 673  ARG   A HG3  1 
ATOM   2512 H HD2  . ARG   A 1 164 ? 21.179 26.561 58.304 1   62.96  ? 673  ARG   A HD2  1 
ATOM   2513 H HD3  . ARG   A 1 164 ? 20.806 26.207 56.805 1   62.778 ? 673  ARG   A HD3  1 
ATOM   2514 H HE   . ARG   A 1 164 ? 20.212 28.749 57.134 1   65.363 ? 673  ARG   A HE   1 
ATOM   2515 H HH11 . ARG   A 1 164 ? 23.12  27.15  56.178 1   68.644 ? 673  ARG   A HH11 1 
ATOM   2516 H HH12 . ARG   A 1 164 ? 23.786 27.906 57.335 1   68.668 ? 673  ARG   A HH12 1 
ATOM   2517 H HH21 . ARG   A 1 164 ? 21.63  30.32  56.032 1   71.463 ? 673  ARG   A HH21 1 
ATOM   2518 H HH22 . ARG   A 1 164 ? 22.906 30.36  56.883 1   71.502 ? 673  ARG   A HH22 1 
ATOM   2519 N N    . ASN   A 1 165 ? 17.289 22.714 56.741 1   55.293 ? 674  ASN   A N    1 
ATOM   2520 C CA   . ASN   A 1 165 ? 17.058 21.278 56.682 1   55.647 ? 674  ASN   A CA   1 
ATOM   2521 C C    . ASN   A 1 165 ? 15.932 21.019 55.68  1   59.417 ? 674  ASN   A C    1 
ATOM   2522 O O    . ASN   A 1 165 ? 14.778 20.847 56.08  1   60.515 ? 674  ASN   A O    1 
ATOM   2523 C CB   . ASN   A 1 165 ? 16.747 20.706 58.064 1   53.38  ? 674  ASN   A CB   1 
ATOM   2524 C CG   . ASN   A 1 165 ? 16.561 19.203 58.058 1   54.951 ? 674  ASN   A CG   1 
ATOM   2525 O OD1  . ASN   A 1 165 ? 17.479 18.458 57.701 1   55.325 ? 674  ASN   A OD1  1 
ATOM   2526 N ND2  . ASN   A 1 165 ? 15.395 18.723 58.466 1   57.397 ? 674  ASN   A ND2  1 
ATOM   2527 H H    . ASN   A 1 165 ? 16.639 23.237 57.113 1   54.185 ? 674  ASN   A H    1 
ATOM   2528 H HA   . ASN   A 1 165 ? 17.876 20.84  56.359 1   55.762 ? 674  ASN   A HA   1 
ATOM   2529 H HB2  . ASN   A 1 165 ? 17.477 20.931 58.673 1   54.134 ? 674  ASN   A HB2  1 
ATOM   2530 H HB3  . ASN   A 1 165 ? 15.933 21.127 58.407 1   54.287 ? 674  ASN   A HB3  1 
ATOM   2531 H HD21 . ASN   A 1 165 ? 15.364 17.951 58.902 1   56.628 ? 674  ASN   A HD21 1 
ATOM   2532 H HD22 . ASN   A 1 165 ? 14.648 19.172 58.301 1   56.613 ? 674  ASN   A HD22 1 
ATOM   2533 N N    . PRO   A 1 166 ? 16.219 21.015 54.354 1   62.998 ? 675  PRO   A N    1 
ATOM   2534 C CA   . PRO   A 1 166 ? 15.176 20.849 53.346 1   68.185 ? 675  PRO   A CA   1 
ATOM   2535 C C    . PRO   A 1 166 ? 14.66  19.418 53.209 1   65.208 ? 675  PRO   A C    1 
ATOM   2536 O O    . PRO   A 1 166 ? 15.451 18.477 53.214 1   60.787 ? 675  PRO   A O    1 
ATOM   2537 C CB   . PRO   A 1 166 ? 15.856 21.305 52.05  1   66.454 ? 675  PRO   A CB   1 
ATOM   2538 C CG   . PRO   A 1 166 ? 17.304 20.921 52.287 1   66.582 ? 675  PRO   A CG   1 
ATOM   2539 C CD   . PRO   A 1 166 ? 17.552 21.199 53.75  1   63.117 ? 675  PRO   A CD   1 
ATOM   2540 H HA   . PRO   A 1 166 ? 14.428 21.449 53.551 1   66.247 ? 675  PRO   A HA   1 
ATOM   2541 H HB2  . PRO   A 1 166 ? 15.488 20.839 51.275 1   66.803 ? 675  PRO   A HB2  1 
ATOM   2542 H HB3  . PRO   A 1 166 ? 15.764 22.269 51.926 1   66.45  ? 675  PRO   A HB3  1 
ATOM   2543 H HG2  . PRO   A 1 166 ? 17.449 19.975 52.088 1   65.666 ? 675  PRO   A HG2  1 
ATOM   2544 H HG3  . PRO   A 1 166 ? 17.902 21.457 51.729 1   65.732 ? 675  PRO   A HG3  1 
ATOM   2545 H HD2  . PRO   A 1 166 ? 18.196 20.569 54.127 1   63.706 ? 675  PRO   A HD2  1 
ATOM   2546 H HD3  . PRO   A 1 166 ? 17.872 22.11  53.886 1   63.605 ? 675  PRO   A HD3  1 
ATOM   2547 N N    . SER   A 1 167 ? 13.328 19.283 53.087 1   68.689 ? 676  SER   A N    1 
ATOM   2548 C CA   . SER   A 1 167 ? 12.685 18.071 52.598 1   69.273 ? 676  SER   A CA   1 
ATOM   2549 C C    . SER   A 1 167 ? 12.076 18.353 51.224 1   72.917 ? 676  SER   A C    1 
ATOM   2550 O O    . SER   A 1 167 ? 12.203 19.462 50.698 1   78.781 ? 676  SER   A O    1 
ATOM   2551 C CB   . SER   A 1 167 ? 11.638 17.575 53.567 1   66.62  ? 676  SER   A CB   1 
ATOM   2552 O OG   . SER   A 1 167 ? 10.454 18.358 53.484 1   66.451 ? 676  SER   A OG   1 
ATOM   2553 H H    . SER   A 1 167 ? 12.795 19.986 53.324 1   67.96  ? 676  SER   A H    1 
ATOM   2554 H HA   . SER   A 1 167 ? 13.376 17.368 52.494 1   69.23  ? 676  SER   A HA   1 
ATOM   2555 H HB2  . SER   A 1 167 ? 11.427 16.644 53.367 1   67.181 ? 676  SER   A HB2  1 
ATOM   2556 H HB3  . SER   A 1 167 ? 11.993 17.618 54.475 1   67.173 ? 676  SER   A HB3  1 
ATOM   2557 H HG   . SER   A 1 167 ? 9.884  18.145 54.06  0   30     ? 676  SER   A HG   1 
ATOM   2558 N N    . ASP   A 1 168 ? 11.401 17.343 50.658 1   70.187 ? 677  ASP   A N    1 
ATOM   2559 C CA   . ASP   A 1 168 ? 10.706 17.497 49.39  1   61.636 ? 677  ASP   A CA   1 
ATOM   2560 C C    . ASP   A 1 168 ? 9.463  18.372 49.562 1   58.626 ? 677  ASP   A C    1 
ATOM   2561 O O    . ASP   A 1 168 ? 9.019  18.964 48.587 1   61.046 ? 677  ASP   A O    1 
ATOM   2562 C CB   . ASP   A 1 168 ? 10.362 16.151 48.771 1   60.117 ? 677  ASP   A CB   1 
ATOM   2563 H H    . ASP   A 1 168 ? 11.381 16.53  51.074 1   68.698 ? 677  ASP   A H    1 
ATOM   2564 H HA   . ASP   A 1 168 ? 11.315 17.95  48.763 1   62.471 ? 677  ASP   A HA   1 
ATOM   2565 H HB2  . ASP   A 1 168 ? 11.097 15.669 48.581 0   30     ? 677  ASP   A HB2  1 
ATOM   2566 H HB3  . ASP   A 1 168 ? 9.297  16.081 48.764 0   30     ? 677  ASP   A HB3  1 
ATOM   2567 N N    . LYS   A 1 169 ? 8.92   18.465 50.792 1   56.963 ? 678  LYS   A N    1 
ATOM   2568 C CA   . LYS   A 1 169 ? 7.628  19.1   51.046 1   54.426 ? 678  LYS   A CA   1 
ATOM   2569 C C    . LYS   A 1 169 ? 7.737  20.624 51.166 1   52.681 ? 678  LYS   A C    1 
ATOM   2570 O O    . LYS   A 1 169 ? 6.742  21.284 51.481 1   50.422 ? 678  LYS   A O    1 
ATOM   2571 C CB   . LYS   A 1 169 ? 6.978  18.558 52.328 1   54.291 ? 678  LYS   A CB   1 
ATOM   2572 H H    . LYS   A 1 169 ? 9.374  18.112 51.502 1   56.961 ? 678  LYS   A H    1 
ATOM   2573 H HA   . LYS   A 1 169 ? 7.028  18.891 50.286 1   54.613 ? 678  LYS   A HA   1 
ATOM   2574 H HB2  . LYS   A 1 169 ? 7.673  18.367 52.996 0   30     ? 678  LYS   A HB2  1 
ATOM   2575 H HB3  . LYS   A 1 169 ? 5.979  18.647 52.285 0   30     ? 678  LYS   A HB3  1 
ATOM   2576 N N    . PHE   A 1 170 ? 8.933  21.188 50.929 1   48.002 ? 679  PHE   A N    1 
ATOM   2577 C CA   . PHE   A 1 170 ? 9.112  22.635 50.912 1   42.759 ? 679  PHE   A CA   1 
ATOM   2578 C C    . PHE   A 1 170 ? 10.2   22.997 49.894 1   36.806 ? 679  PHE   A C    1 
ATOM   2579 O O    . PHE   A 1 170 ? 11.383 23.019 50.227 1   33.827 ? 679  PHE   A O    1 
ATOM   2580 C CB   . PHE   A 1 170 ? 9.437  23.149 52.323 1   45.581 ? 679  PHE   A CB   1 
ATOM   2581 C CG   . PHE   A 1 170 ? 9.337  24.665 52.436 1   49.097 ? 679  PHE   A CG   1 
ATOM   2582 C CD1  . PHE   A 1 170 ? 10.41  25.484 52.095 1   47.289 ? 679  PHE   A CD1  1 
ATOM   2583 C CD2  . PHE   A 1 170 ? 8.145  25.268 52.828 1   50.927 ? 679  PHE   A CD2  1 
ATOM   2584 C CE1  . PHE   A 1 170 ? 10.29  26.863 52.148 1   51.269 ? 679  PHE   A CE1  1 
ATOM   2585 C CE2  . PHE   A 1 170 ? 8.034  26.649 52.896 1   50.788 ? 679  PHE   A CE2  1 
ATOM   2586 C CZ   . PHE   A 1 170 ? 9.107  27.443 52.556 1   53.597 ? 679  PHE   A CZ   1 
ATOM   2587 H H    . PHE   A 1 170 ? 9.663  20.656 50.789 1   47.901 ? 679  PHE   A H    1 
ATOM   2588 H HA   . PHE   A 1 170 ? 8.259  23.052 50.618 1   42.957 ? 679  PHE   A HA   1 
ATOM   2589 H HB2  . PHE   A 1 170 ? 8.811  22.737 52.96  1   45.679 ? 679  PHE   A HB2  1 
ATOM   2590 H HB3  . PHE   A 1 170 ? 10.348 22.867 52.562 1   45.615 ? 679  PHE   A HB3  1 
ATOM   2591 H HD1  . PHE   A 1 170 ? 11.22  25.096 51.806 1   48.545 ? 679  PHE   A HD1  1 
ATOM   2592 H HD2  . PHE   A 1 170 ? 7.404  24.728 53.053 1   50.422 ? 679  PHE   A HD2  1 
ATOM   2593 H HE1  . PHE   A 1 170 ? 11.028 27.407 51.927 1   50.723 ? 679  PHE   A HE1  1 
ATOM   2594 H HE2  . PHE   A 1 170 ? 7.222  27.044 53.173 1   51.414 ? 679  PHE   A HE2  1 
ATOM   2595 H HZ   . PHE   A 1 170 ? 9.036  28.381 52.608 1   52.175 ? 679  PHE   A HZ   1 
ATOM   2596 N N    . ILE   A 1 171 ? 9.786  23.33  48.663 1   30.473 ? 680  ILE   A N    1 
ATOM   2597 C CA   . ILE   A 1 171 ? 10.709 23.621 47.572 1   30.026 ? 680  ILE   A CA   1 
ATOM   2598 C C    . ILE   A 1 171 ? 11.042 25.112 47.578 1   27.23  ? 680  ILE   A C    1 
ATOM   2599 O O    . ILE   A 1 171 ? 10.134 25.955 47.584 1   24.722 ? 680  ILE   A O    1 
ATOM   2600 C CB   . ILE   A 1 171 ? 10.111 23.186 46.217 1   30.55  ? 680  ILE   A CB   1 
ATOM   2601 C CG1  . ILE   A 1 171 ? 9.836  21.691 46.188 1   33.101 ? 680  ILE   A CG1  1 
ATOM   2602 C CG2  . ILE   A 1 171 ? 11.002 23.592 45.043 1   31.582 ? 680  ILE   A CG2  1 
ATOM   2603 C CD1  . ILE   A 1 171 ? 8.784  21.295 45.176 1   35.143 ? 680  ILE   A CD1  1 
ATOM   2604 H H    . ILE   A 1 171 ? 8.888  23.378 48.497 1   31.912 ? 680  ILE   A H    1 
ATOM   2605 H HA   . ILE   A 1 171 ? 11.529 23.115 47.72  1   29.838 ? 680  ILE   A HA   1 
ATOM   2606 H HB   . ILE   A 1 171 ? 9.254  23.645 46.113 1   31.149 ? 680  ILE   A HB   1 
ATOM   2607 H HG12 . ILE   A 1 171 ? 10.669 21.22  45.979 1   32.937 ? 680  ILE   A HG12 1 
ATOM   2608 H HG13 . ILE   A 1 171 ? 9.543  21.403 47.077 1   32.919 ? 680  ILE   A HG13 1 
ATOM   2609 H HG21 . ILE   A 1 171 ? 10.771 23.067 44.258 1   31.262 ? 680  ILE   A HG21 1 
ATOM   2610 H HG22 . ILE   A 1 171 ? 11.934 23.435 45.272 1   31.223 ? 680  ILE   A HG22 1 
ATOM   2611 H HG23 . ILE   A 1 171 ? 10.874 24.535 44.846 1   31.016 ? 680  ILE   A HG23 1 
ATOM   2612 H HD11 . ILE   A 1 171 ? 7.977  21.826 45.317 1   34.496 ? 680  ILE   A HD11 1 
ATOM   2613 H HD12 . ILE   A 1 171 ? 8.57   20.348 45.283 1   34.514 ? 680  ILE   A HD12 1 
ATOM   2614 H HD13 . ILE   A 1 171 ? 9.12   21.451 44.274 1   34.496 ? 680  ILE   A HD13 1 
ATOM   2615 N N    . TYR   A 1 172 ? 12.348 25.417 47.54  1   22.05  ? 681  TYR   A N    1 
ATOM   2616 C CA   . TYR   A 1 172 ? 12.81  26.784 47.378 1   22.927 ? 681  TYR   A CA   1 
ATOM   2617 C C    . TYR   A 1 172 ? 13.84  26.809 46.265 1   20.741 ? 681  TYR   A C    1 
ATOM   2618 O O    . TYR   A 1 172 ? 14.396 25.768 45.922 1   17.668 ? 681  TYR   A O    1 
ATOM   2619 C CB   . TYR   A 1 172 ? 13.348 27.397 48.673 1   24.561 ? 681  TYR   A CB   1 
ATOM   2620 C CG   . TYR   A 1 172 ? 14.487 26.623 49.302 1   27.365 ? 681  TYR   A CG   1 
ATOM   2621 C CD1  . TYR   A 1 172 ? 14.238 25.615 50.217 1   28.709 ? 681  TYR   A CD1  1 
ATOM   2622 C CD2  . TYR   A 1 172 ? 15.806 26.887 48.961 1   31.219 ? 681  TYR   A CD2  1 
ATOM   2623 C CE1  . TYR   A 1 172 ? 15.272 24.899 50.791 1   32.338 ? 681  TYR   A CE1  1 
ATOM   2624 C CE2  . TYR   A 1 172 ? 16.847 26.161 49.51  1   34.34  ? 681  TYR   A CE2  1 
ATOM   2625 C CZ   . TYR   A 1 172 ? 16.58  25.171 50.435 1   37.895 ? 681  TYR   A CZ   1 
ATOM   2626 O OH   . TYR   A 1 172 ? 17.612 24.476 51.01  1   45.943 ? 681  TYR   A OH   1 
ATOM   2627 H H    . TYR   A 1 172 ? 12.969 24.751 47.621 1   23.741 ? 681  TYR   A H    1 
ATOM   2628 H HA   . TYR   A 1 172 ? 12.037 27.331 47.084 1   22.551 ? 681  TYR   A HA   1 
ATOM   2629 H HB2  . TYR   A 1 172 ? 13.653 28.312 48.482 1   24.766 ? 681  TYR   A HB2  1 
ATOM   2630 H HB3  . TYR   A 1 172 ? 12.611 27.454 49.319 1   24.679 ? 681  TYR   A HB3  1 
ATOM   2631 H HD1  . TYR   A 1 172 ? 13.348 25.424 50.466 1   29.285 ? 681  TYR   A HD1  1 
ATOM   2632 H HD2  . TYR   A 1 172 ? 15.995 27.558 48.326 1   30.987 ? 681  TYR   A HD2  1 
ATOM   2633 H HE1  . TYR   A 1 172 ? 15.085 24.225 51.42  1   32.875 ? 681  TYR   A HE1  1 
ATOM   2634 H HE2  . TYR   A 1 172 ? 17.738 26.361 49.277 1   34.352 ? 681  TYR   A HE2  1 
ATOM   2635 H HH   . TYR   A 1 172 ? 17.3   23.917 51.572 0   30     ? 681  TYR   A HH   1 
ATOM   2636 N N    . ALA   A 1 173 ? 14.019 27.994 45.67  1   16.56  ? 682  ALA   A N    1 
ATOM   2637 C CA   . ALA   A 1 173 ? 14.816 28.125 44.46  1   14.699 ? 682  ALA   A CA   1 
ATOM   2638 C C    . ALA   A 1 173 ? 15.259 29.568 44.232 1   14.248 ? 682  ALA   A C    1 
ATOM   2639 O O    . ALA   A 1 173 ? 14.743 30.494 44.86  1   13.646 ? 682  ALA   A O    1 
ATOM   2640 C CB   . ALA   A 1 173 ? 14.011 27.623 43.288 1   14.963 ? 682  ALA   A CB   1 
ATOM   2641 H H    . ALA   A 1 173 ? 13.632 28.741 46.028 1   17.066 ? 682  ALA   A H    1 
ATOM   2642 H HA   . ALA   A 1 173 ? 15.633 27.562 44.56  1   15.036 ? 682  ALA   A HA   1 
ATOM   2643 H HB1  . ALA   A 1 173 ? 13.86  26.667 43.379 1   14.914 ? 682  ALA   A HB1  1 
ATOM   2644 H HB2  . ALA   A 1 173 ? 13.155 28.082 43.258 1   14.905 ? 682  ALA   A HB2  1 
ATOM   2645 H HB3  . ALA   A 1 173 ? 14.495 27.793 42.462 1   14.911 ? 682  ALA   A HB3  1 
ATOM   2646 N N    . THR   A 1 174 ? 16.231 29.739 43.314 1   13.315 ? 683  THR   A N    1 
ATOM   2647 C CA   . THR   A 1 174 ? 16.567 31.048 42.773 1   12.95  ? 683  THR   A CA   1 
ATOM   2648 C C    . THR   A 1 174 ? 16.577 30.946 41.254 1   13.12  ? 683  THR   A C    1 
ATOM   2649 O O    . THR   A 1 174 ? 15.952 30.042 40.665 1   13.692 ? 683  THR   A O    1 
ATOM   2650 C CB   . THR   A 1 174 ? 17.883 31.535 43.389 1   12.704 ? 683  THR   A CB   1 
ATOM   2651 O OG1  . THR   A 1 174 ? 18.064 32.925 43.078 1   13.326 ? 683  THR   A OG1  1 
ATOM   2652 C CG2  . THR   A 1 174 ? 19.072 30.695 42.951 1   13.375 ? 683  THR   A CG2  1 
ATOM   2653 H H    . THR   A 1 174 ? 16.694 29.01  43.017 1   13.481 ? 683  THR   A H    1 
ATOM   2654 H HA   . THR   A 1 174 ? 15.86  31.676 43.032 1   13.01  ? 683  THR   A HA   1 
ATOM   2655 H HB   . THR   A 1 174 ? 17.81  31.444 44.369 1   12.992 ? 683  THR   A HB   1 
ATOM   2656 H HG1  . THR   A 1 174 ? 18.096 33.027 42.218 0   30     ? 683  THR   A HG1  1 
ATOM   2657 H HG21 . THR   A 1 174 ? 19.849 30.935 43.483 1   13.176 ? 683  THR   A HG21 1 
ATOM   2658 H HG22 . THR   A 1 174 ? 19.261 30.86  42.012 1   13.175 ? 683  THR   A HG22 1 
ATOM   2659 H HG23 . THR   A 1 174 ? 18.872 29.754 43.081 1   13.186 ? 683  THR   A HG23 1 
ATOM   2660 N N    . VAL   A 1 175 ? 17.245 31.903 40.619 1   13.053 ? 684  VAL   A N    1 
ATOM   2661 C CA   . VAL   A 1 175 ? 17.316 31.971 39.173 1   12.318 ? 684  VAL   A CA   1 
ATOM   2662 C C    . VAL   A 1 175 ? 18.664 31.398 38.759 1   13.601 ? 684  VAL   A C    1 
ATOM   2663 O O    . VAL   A 1 175 ? 19.703 31.717 39.36  1   13.168 ? 684  VAL   A O    1 
ATOM   2664 C CB   . VAL   A 1 175 ? 17.113 33.391 38.614 1   12.364 ? 684  VAL   A CB   1 
ATOM   2665 C CG1  . VAL   A 1 175 ? 17.18  33.432 37.095 1   12.325 ? 684  VAL   A CG1  1 
ATOM   2666 C CG2  . VAL   A 1 175 ? 15.793 34.004 39.093 1   12.095 ? 684  VAL   A CG2  1 
ATOM   2667 H H    . VAL   A 1 175 ? 17.669 32.55  41.105 1   12.897 ? 684  VAL   A H    1 
ATOM   2668 H HA   . VAL   A 1 175 ? 16.613 31.402 38.808 1   12.751 ? 684  VAL   A HA   1 
ATOM   2669 H HB   . VAL   A 1 175 ? 17.848 33.947 38.961 1   12.288 ? 684  VAL   A HB   1 
ATOM   2670 H HG11 . VAL   A 1 175 ? 16.632 32.718 36.726 1   12.362 ? 684  VAL   A HG11 1 
ATOM   2671 H HG12 . VAL   A 1 175 ? 18.1   33.315 36.806 1   12.361 ? 684  VAL   A HG12 1 
ATOM   2672 H HG13 . VAL   A 1 175 ? 16.849 34.289 36.777 1   12.344 ? 684  VAL   A HG13 1 
ATOM   2673 H HG21 . VAL   A 1 175 ? 15.67  34.876 38.681 1   12.175 ? 684  VAL   A HG21 1 
ATOM   2674 H HG22 . VAL   A 1 175 ? 15.812 34.104 40.06  1   12.177 ? 684  VAL   A HG22 1 
ATOM   2675 H HG23 . VAL   A 1 175 ? 15.055 33.422 38.844 1   12.174 ? 684  VAL   A HG23 1 
ATOM   2676 N N    . LYS   A 1 176 ? 18.593 30.547 37.732 1   14.783 ? 685  LYS   A N    1 
ATOM   2677 C CA   . LYS   A 1 176 ? 19.759 29.905 37.15  1   17.511 ? 685  LYS   A CA   1 
ATOM   2678 C C    . LYS   A 1 176 ? 20.675 30.948 36.529 1   15.368 ? 685  LYS   A C    1 
ATOM   2679 O O    . LYS   A 1 176 ? 20.207 31.922 35.936 1   15.384 ? 685  LYS   A O    1 
ATOM   2680 C CB   . LYS   A 1 176 ? 19.367 28.99  35.996 1   20.009 ? 685  LYS   A CB   1 
ATOM   2681 C CG   . LYS   A 1 176 ? 18.684 27.731 36.447 1   25.666 ? 685  LYS   A CG   1 
ATOM   2682 C CD   . LYS   A 1 176 ? 18.524 26.767 35.274 1   32.683 ? 685  LYS   A CD   1 
ATOM   2683 C CE   . LYS   A 1 176 ? 17.752 25.513 35.584 1   35.807 ? 685  LYS   A CE   1 
ATOM   2684 N NZ   . LYS   A 1 176 ? 17.554 24.778 34.332 1   39.077 ? 685  LYS   A NZ   1 
ATOM   2685 H H    . LYS   A 1 176 ? 17.774 30.358 37.374 1   15.081 ? 685  LYS   A H    1 
ATOM   2686 H HA   . LYS   A 1 176 ? 20.241 29.403 37.854 1   16.918 ? 685  LYS   A HA   1 
ATOM   2687 H HB2  . LYS   A 1 176 ? 18.766 29.475 35.391 1   20.535 ? 685  LYS   A HB2  1 
ATOM   2688 H HB3  . LYS   A 1 176 ? 20.172 28.746 35.49  1   20.584 ? 685  LYS   A HB3  1 
ATOM   2689 H HG2  . LYS   A 1 176 ? 19.221 27.307 37.152 1   25.586 ? 685  LYS   A HG2  1 
ATOM   2690 H HG3  . LYS   A 1 176 ? 17.801 27.955 36.814 1   25.586 ? 685  LYS   A HG3  1 
ATOM   2691 H HD2  . LYS   A 1 176 ? 18.073 27.242 34.542 1   31.626 ? 685  LYS   A HD2  1 
ATOM   2692 H HD3  . LYS   A 1 176 ? 19.417 26.516 34.953 1   31.596 ? 685  LYS   A HD3  1 
ATOM   2693 H HE2  . LYS   A 1 176 ? 18.246 24.958 36.215 1   35.778 ? 685  LYS   A HE2  1 
ATOM   2694 H HE3  . LYS   A 1 176 ? 16.887 25.736 35.968 1   35.657 ? 685  LYS   A HE3  1 
ATOM   2695 H HZ1  . LYS   A 1 176 ? 18.355 24.609 33.943 1   37.986 ? 685  LYS   A HZ1  1 
ATOM   2696 H HZ2  . LYS   A 1 176 ? 17.044 25.267 33.765 1   37.951 ? 685  LYS   A HZ2  1 
ATOM   2697 H HZ3  . LYS   A 1 176 ? 17.136 23.992 34.502 1   38.013 ? 685  LYS   A HZ3  1 
ATOM   2698 N N    . GLN   A 1 177 ? 21.977 30.704 36.681 1   14.663 ? 686  GLN   A N    1 
ATOM   2699 C CA   . GLN   A 1 177 ? 23.024 31.516 36.077 1   16.007 ? 686  GLN   A CA   1 
ATOM   2700 C C    . GLN   A 1 177 ? 22.905 32.986 36.512 1   15.073 ? 686  GLN   A C    1 
ATOM   2701 O O    . GLN   A 1 177 ? 23.174 33.901 35.737 1   14.081 ? 686  GLN   A O    1 
ATOM   2702 C CB   . GLN   A 1 177 ? 23.053 31.237 34.572 1   18.049 ? 686  GLN   A CB   1 
ATOM   2703 C CG   . GLN   A 1 177 ? 23.298 29.762 34.241 1   20.903 ? 686  GLN   A CG   1 
ATOM   2704 C CD   . GLN   A 1 177 ? 22.963 29.42  32.808 1   28.275 ? 686  GLN   A CD   1 
ATOM   2705 O OE1  . GLN   A 1 177 ? 22.791 30.296 31.947 1   29.671 ? 686  GLN   A OE1  1 
ATOM   2706 N NE2  . GLN   A 1 177 ? 22.953 28.127 32.516 1   33.421 ? 686  GLN   A NE2  1 
ATOM   2707 H H    . GLN   A 1 177 ? 22.23  29.989 37.191 1   15.157 ? 686  GLN   A H    1 
ATOM   2708 H HA   . GLN   A 1 177 ? 23.886 31.181 36.427 1   15.941 ? 686  GLN   A HA   1 
ATOM   2709 H HB2  . GLN   A 1 177 ? 22.199 31.517 34.181 1   18.218 ? 686  GLN   A HB2  1 
ATOM   2710 H HB3  . GLN   A 1 177 ? 23.761 31.778 34.163 1   18.147 ? 686  GLN   A HB3  1 
ATOM   2711 H HG2  . GLN   A 1 177 ? 24.241 29.545 34.406 1   21.683 ? 686  GLN   A HG2  1 
ATOM   2712 H HG3  . GLN   A 1 177 ? 22.755 29.2   34.833 1   21.645 ? 686  GLN   A HG3  1 
ATOM   2713 H HE21 . GLN   A 1 177 ? 22.71  27.859 31.706 1   31.704 ? 686  GLN   A HE21 1 
ATOM   2714 H HE22 . GLN   A 1 177 ? 23.187 27.53  33.129 1   31.64  ? 686  GLN   A HE22 1 
ATOM   2715 N N    . SER   A 1 178 ? 22.6   33.186 37.81  1   15.852 ? 687  SER   A N    1 
ATOM   2716 C CA   . SER   A 1 178 ? 22.778 34.451 38.497 1   15.483 ? 687  SER   A CA   1 
ATOM   2717 C C    . SER   A 1 178 ? 23.912 34.285 39.509 1   16.982 ? 687  SER   A C    1 
ATOM   2718 O O    . SER   A 1 178 ? 24.458 33.196 39.646 1   19.028 ? 687  SER   A O    1 
ATOM   2719 C CB   . SER   A 1 178 ? 21.482 34.878 39.161 1   16.52  ? 687  SER   A CB   1 
ATOM   2720 O OG   . SER   A 1 178 ? 21.141 33.96  40.188 1   14.379 ? 687  SER   A OG   1 
ATOM   2721 H H    . SER   A 1 178 ? 22.267 32.484 38.29  1   15.574 ? 687  SER   A H    1 
ATOM   2722 H HA   . SER   A 1 178 ? 23.041 35.141 37.837 1   15.99  ? 687  SER   A HA   1 
ATOM   2723 H HB2  . SER   A 1 178 ? 21.589 35.768 39.541 1   15.647 ? 687  SER   A HB2  1 
ATOM   2724 H HB3  . SER   A 1 178 ? 20.768 34.907 38.496 1   15.731 ? 687  SER   A HB3  1 
ATOM   2725 H HG   . SER   A 1 178 ? 20.422 34.207 40.543 0   30     ? 687  SER   A HG   1 
ATOM   2726 N N    . SER   A 1 179 ? 24.271 35.356 40.217 1   14.463 ? 688  SER   A N    1 
ATOM   2727 C CA   . SER   A 1 179 ? 25.298 35.266 41.23  1   15.874 ? 688  SER   A CA   1 
ATOM   2728 C C    . SER   A 1 179 ? 24.805 34.641 42.539 1   16.788 ? 688  SER   A C    1 
ATOM   2729 O O    . SER   A 1 179 ? 25.608 34.521 43.45  1   16.61  ? 688  SER   A O    1 
ATOM   2730 C CB   . SER   A 1 179 ? 25.894 36.616 41.525 1   15.213 ? 688  SER   A CB   1 
ATOM   2731 O OG   . SER   A 1 179 ? 26.932 36.91  40.626 1   17.368 ? 688  SER   A OG   1 
ATOM   2732 H H    . SER   A 1 179 ? 23.865 36.16  40.063 1   15.359 ? 688  SER   A H    1 
ATOM   2733 H HA   . SER   A 1 179 ? 26.021 34.688 40.875 1   15.66  ? 688  SER   A HA   1 
ATOM   2734 H HB2  . SER   A 1 179 ? 25.205 37.299 41.454 1   15.8   ? 688  SER   A HB2  1 
ATOM   2735 H HB3  . SER   A 1 179 ? 26.243 36.629 42.436 1   15.853 ? 688  SER   A HB3  1 
ATOM   2736 H HG   . SER   A 1 179 ? 27.245 37.681 40.808 0   30     ? 688  SER   A HG   1 
ATOM   2737 N N    . VAL   A 1 180 ? 23.537 34.227 42.639 1   18.217 ? 689  VAL   A N    1 
ATOM   2738 C CA   . VAL   A 1 180 ? 22.999 33.741 43.9   1   20.383 ? 689  VAL   A CA   1 
ATOM   2739 C C    . VAL   A 1 180 ? 23.62  32.383 44.228 1   23.727 ? 689  VAL   A C    1 
ATOM   2740 O O    . VAL   A 1 180 ? 24.055 32.178 45.354 1   24.045 ? 689  VAL   A O    1 
ATOM   2741 C CB   . VAL   A 1 180 ? 21.461 33.686 43.936 1   18.618 ? 689  VAL   A CB   1 
ATOM   2742 C CG1  . VAL   A 1 180 ? 20.947 33.1   45.249 1   18.466 ? 689  VAL   A CG1  1 
ATOM   2743 C CG2  . VAL   A 1 180 ? 20.826 35.048 43.678 1   18.371 ? 689  VAL   A CG2  1 
ATOM   2744 H H    . VAL   A 1 180 ? 22.99  34.251 41.909 1   18.284 ? 689  VAL   A H    1 
ATOM   2745 H HA   . VAL   A 1 180 ? 23.281 34.367 44.595 1   20.156 ? 689  VAL   A HA   1 
ATOM   2746 H HB   . VAL   A 1 180 ? 21.177 33.082 43.209 1   18.858 ? 689  VAL   A HB   1 
ATOM   2747 H HG11 . VAL   A 1 180 ? 21.494 33.423 45.985 1   18.584 ? 689  VAL   A HG11 1 
ATOM   2748 H HG12 . VAL   A 1 180 ? 20.993 32.13  45.213 1   18.549 ? 689  VAL   A HG12 1 
ATOM   2749 H HG13 . VAL   A 1 180 ? 20.024 33.373 45.39  1   18.53  ? 689  VAL   A HG13 1 
ATOM   2750 H HG21 . VAL   A 1 180 ? 19.858 34.968 43.714 1   18.424 ? 689  VAL   A HG21 1 
ATOM   2751 H HG22 . VAL   A 1 180 ? 21.09  35.368 42.799 1   18.422 ? 689  VAL   A HG22 1 
ATOM   2752 H HG23 . VAL   A 1 180 ? 21.124 35.678 44.355 1   18.362 ? 689  VAL   A HG23 1 
ATOM   2753 N N    . ASP   A 1 181 ? 23.707 31.452 43.275 1   27.459 ? 690  ASP   A N    1 
ATOM   2754 C CA   . ASP   A 1 181 ? 24.315 30.159 43.602 1   35.422 ? 690  ASP   A CA   1 
ATOM   2755 C C    . ASP   A 1 181 ? 25.78  30.308 44.036 1   37.416 ? 690  ASP   A C    1 
ATOM   2756 O O    . ASP   A 1 181 ? 26.245 29.555 44.896 1   42.875 ? 690  ASP   A O    1 
ATOM   2757 C CB   . ASP   A 1 181 ? 24.16  29.133 42.487 1   39.447 ? 690  ASP   A CB   1 
ATOM   2758 C CG   . ASP   A 1 181 ? 22.808 28.432 42.379 1   41.473 ? 690  ASP   A CG   1 
ATOM   2759 O OD1  . ASP   A 1 181 ? 22.024 28.448 43.361 1   37.239 ? 690  ASP   A OD1  1 
ATOM   2760 O OD2  . ASP   A 1 181 ? 22.537 27.875 41.294 1   46.434 ? 690  ASP   A OD2  1 
ATOM   2761 H H    . ASP   A 1 181 ? 23.392 31.609 42.431 1   28.116 ? 690  ASP   A H    1 
ATOM   2762 H HA   . ASP   A 1 181 ? 23.822 29.789 44.368 1   34.66  ? 690  ASP   A HA   1 
ATOM   2763 H HB2  . ASP   A 1 181 ? 24.345 29.573 41.631 1   38.773 ? 690  ASP   A HB2  1 
ATOM   2764 H HB3  . ASP   A 1 181 ? 24.842 28.441 42.611 1   39.038 ? 690  ASP   A HB3  1 
ATOM   2765 N N    . ILE   A 1 182 ? 26.494 31.284 43.454 1   39.356 ? 691  ILE   A N    1 
ATOM   2766 C CA   . ILE   A 1 182 ? 27.896 31.558 43.764 1   41.489 ? 691  ILE   A CA   1 
ATOM   2767 C C    . ILE   A 1 182 ? 28.061 31.939 45.242 1   42.997 ? 691  ILE   A C    1 
ATOM   2768 O O    . ILE   A 1 182 ? 29.009 31.496 45.903 1   44.363 ? 691  ILE   A O    1 
ATOM   2769 C CB   . ILE   A 1 182 ? 28.469 32.652 42.827 1   40.433 ? 691  ILE   A CB   1 
ATOM   2770 H H    . ILE   A 1 182 ? 26.085 31.802 42.822 1   39.122 ? 691  ILE   A H    1 
ATOM   2771 H HA   . ILE   A 1 182 ? 28.401 30.737 43.607 1   41.141 ? 691  ILE   A HA   1 
ATOM   2772 H HB   . ILE   A 1 182 ? 27.697 33.134 42.458 0   30     ? 691  ILE   A HB   1 
ATOM   2773 N N    . TYR   A 1 183 ? 27.153 32.781 45.758 1   38.345 ? 692  TYR   A N    1 
ATOM   2774 C CA   . TYR   A 1 183 ? 27.23  33.257 47.132 1   38.551 ? 692  TYR   A CA   1 
ATOM   2775 C C    . TYR   A 1 183 ? 26.934 32.147 48.132 1   39.349 ? 692  TYR   A C    1 
ATOM   2776 O O    . TYR   A 1 183 ? 27.502 32.15  49.219 1   50.087 ? 692  TYR   A O    1 
ATOM   2777 C CB   . TYR   A 1 183 ? 26.253 34.406 47.396 1   39.797 ? 692  TYR   A CB   1 
ATOM   2778 C CG   . TYR   A 1 183 ? 26.845 35.79  47.184 1   40.516 ? 692  TYR   A CG   1 
ATOM   2779 C CD1  . TYR   A 1 183 ? 27.012 36.316 45.904 1   40.101 ? 692  TYR   A CD1  1 
ATOM   2780 C CD2  . TYR   A 1 183 ? 27.202 36.582 48.267 1   37.734 ? 692  TYR   A CD2  1 
ATOM   2781 C CE1  . TYR   A 1 183 ? 27.526 37.59  45.715 1   40.491 ? 692  TYR   A CE1  1 
ATOM   2782 C CE2  . TYR   A 1 183 ? 27.722 37.854 48.087 1   41.926 ? 692  TYR   A CE2  1 
ATOM   2783 C CZ   . TYR   A 1 183 ? 27.885 38.356 46.807 1   41.153 ? 692  TYR   A CZ   1 
ATOM   2784 O OH   . TYR   A 1 183 ? 28.386 39.608 46.622 1   45.672 ? 692  TYR   A OH   1 
ATOM   2785 H H    . TYR   A 1 183 ? 26.466 33.071 45.23  1   39.471 ? 692  TYR   A H    1 
ATOM   2786 H HA   . TYR   A 1 183 ? 28.153 33.589 47.295 1   38.935 ? 692  TYR   A HA   1 
ATOM   2787 H HB2  . TYR   A 1 183 ? 25.476 34.298 46.803 1   39.644 ? 692  TYR   A HB2  1 
ATOM   2788 H HB3  . TYR   A 1 183 ? 25.933 34.338 48.322 1   39.575 ? 692  TYR   A HB3  1 
ATOM   2789 H HD1  . TYR   A 1 183 ? 26.767 35.8   45.154 1   40.006 ? 692  TYR   A HD1  1 
ATOM   2790 H HD2  . TYR   A 1 183 ? 27.093 36.247 49.143 1   39.178 ? 692  TYR   A HD2  1 
ATOM   2791 H HE1  . TYR   A 1 183 ? 27.638 37.931 44.844 1   40.573 ? 692  TYR   A HE1  1 
ATOM   2792 H HE2  . TYR   A 1 183 ? 27.963 38.377 48.832 1   40.748 ? 692  TYR   A HE2  1 
ATOM   2793 H HH   . TYR   A 1 183 ? 28.472 39.79  45.801 0   30     ? 692  TYR   A HH   1 
ATOM   2794 N N    . PHE   A 1 184 ? 26.021 31.236 47.788 1   36.704 ? 693  PHE   A N    1 
ATOM   2795 C CA   . PHE   A 1 184 ? 25.699 30.108 48.649 1   38.836 ? 693  PHE   A CA   1 
ATOM   2796 C C    . PHE   A 1 184 ? 26.827 29.074 48.633 1   48.018 ? 693  PHE   A C    1 
ATOM   2797 O O    . PHE   A 1 184 ? 27.138 28.502 49.678 1   49.203 ? 693  PHE   A O    1 
ATOM   2798 C CB   . PHE   A 1 184 ? 24.368 29.479 48.222 1   36.317 ? 693  PHE   A CB   1 
ATOM   2799 C CG   . PHE   A 1 184 ? 23.148 30.214 48.761 1   34.318 ? 693  PHE   A CG   1 
ATOM   2800 C CD1  . PHE   A 1 184 ? 22.742 31.423 48.203 1   30.549 ? 693  PHE   A CD1  1 
ATOM   2801 C CD2  . PHE   A 1 184 ? 22.44  29.723 49.858 1   33.675 ? 693  PHE   A CD2  1 
ATOM   2802 C CE1  . PHE   A 1 184 ? 21.633 32.094 48.697 1   29.151 ? 693  PHE   A CE1  1 
ATOM   2803 C CE2  . PHE   A 1 184 ? 21.346 30.413 50.355 1   31.604 ? 693  PHE   A CE2  1 
ATOM   2804 C CZ   . PHE   A 1 184 ? 20.943 31.594 49.768 1   27.569 ? 693  PHE   A CZ   1 
ATOM   2805 H H    . PHE   A 1 184 ? 25.579 31.323 46.993 1   37.783 ? 693  PHE   A H    1 
ATOM   2806 H HA   . PHE   A 1 184 ? 25.598 30.445 49.578 1   39.471 ? 693  PHE   A HA   1 
ATOM   2807 H HB2  . PHE   A 1 184 ? 24.326 29.464 47.24  1   36.437 ? 693  PHE   A HB2  1 
ATOM   2808 H HB3  . PHE   A 1 184 ? 24.344 28.55  48.541 1   36.536 ? 693  PHE   A HB3  1 
ATOM   2809 H HD1  . PHE   A 1 184 ? 23.208 31.773 47.462 1   30.991 ? 693  PHE   A HD1  1 
ATOM   2810 H HD2  . PHE   A 1 184 ? 22.708 28.912 50.262 1   33.247 ? 693  PHE   A HD2  1 
ATOM   2811 H HE1  . PHE   A 1 184 ? 21.363 32.907 48.302 1   29.065 ? 693  PHE   A HE1  1 
ATOM   2812 H HE2  . PHE   A 1 184 ? 20.864 30.064 51.088 1   31.043 ? 693  PHE   A HE2  1 
ATOM   2813 H HZ   . PHE   A 1 184 ? 20.195 32.06  50.106 1   28.903 ? 693  PHE   A HZ   1 
ATOM   2814 N N    . ARG   A 1 185 ? 27.411 28.835 47.443 1   54.337 ? 694  ARG   A N    1 
ATOM   2815 C CA   . ARG   A 1 185 ? 28.561 27.952 47.271 1   57.74  ? 694  ARG   A CA   1 
ATOM   2816 C C    . ARG   A 1 185 ? 29.827 28.529 47.926 1   60.57  ? 694  ARG   A C    1 
ATOM   2817 O O    . ARG   A 1 185 ? 30.704 27.774 48.332 1   68.517 ? 694  ARG   A O    1 
ATOM   2818 C CB   . ARG   A 1 185 ? 28.762 27.638 45.781 1   49.677 ? 694  ARG   A CB   1 
ATOM   2819 H H    . ARG   A 1 185 ? 27.066 29.243 46.702 1   53.202 ? 694  ARG   A H    1 
ATOM   2820 H HA   . ARG   A 1 185 ? 28.352 27.096 47.725 1   55.954 ? 694  ARG   A HA   1 
ATOM   2821 H HB2  . ARG   A 1 185 ? 29.718 27.59  45.593 0   30     ? 694  ARG   A HB2  1 
ATOM   2822 H HB3  . ARG   A 1 185 ? 27.878 27.537 45.336 0   30     ? 694  ARG   A HB3  1 
ATOM   2823 N N    . ARG   A 1 186 ? 29.929 29.86  48.066 1   67.207 ? 695  ARG   A N    1 
ATOM   2824 C CA   . ARG   A 1 186 ? 31.122 30.502 48.617 1   64.669 ? 695  ARG   A CA   1 
ATOM   2825 C C    . ARG   A 1 186 ? 31.161 30.468 50.153 1   69.412 ? 695  ARG   A C    1 
ATOM   2826 O O    . ARG   A 1 186 ? 32.073 31.048 50.746 1   69.542 ? 695  ARG   A O    1 
ATOM   2827 C CB   . ARG   A 1 186 ? 31.263 31.957 48.146 1   63.68  ? 695  ARG   A CB   1 
ATOM   2828 H H    . ARG   A 1 186 ? 29.232 30.388 47.803 1   64.581 ? 695  ARG   A H    1 
ATOM   2829 H HA   . ARG   A 1 186 ? 31.913 30.008 48.283 1   65.801 ? 695  ARG   A HA   1 
ATOM   2830 H HB2  . ARG   A 1 186 ? 32.221 32.133 48.056 0   30     ? 695  ARG   A HB2  1 
ATOM   2831 H HB3  . ARG   A 1 186 ? 30.369 32.291 48.005 0   30     ? 695  ARG   A HB3  1 
ATOM   2832 N N    . GLN   A 1 187 ? 30.182 29.822 50.806 1   64.926 ? 696  GLN   A N    1 
ATOM   2833 C CA   . GLN   A 1 187 ? 30.269 29.536 52.233 1   68.001 ? 696  GLN   A CA   1 
ATOM   2834 C C    . GLN   A 1 187 ? 29.986 28.049 52.444 1   73.522 ? 696  GLN   A C    1 
ATOM   2835 O O    . GLN   A 1 187 ? 29.021 27.517 51.899 1   81.011 ? 696  GLN   A O    1 
ATOM   2836 C CB   . GLN   A 1 187 ? 29.333 30.421 53.061 1   62.233 ? 696  GLN   A CB   1 
ATOM   2837 H H    . GLN   A 1 187 ? 29.43  29.566 50.355 1   66.653 ? 696  GLN   A H    1 
ATOM   2838 H HA   . GLN   A 1 187 ? 31.197 29.718 52.529 1   67.401 ? 696  GLN   A HA   1 
ATOM   2839 H HB2  . GLN   A 1 187 ? 29.888 31.014 53.589 0   30     ? 696  GLN   A HB2  1 
ATOM   2840 H HB3  . GLN   A 1 187 ? 28.416 30.179 52.825 0   30     ? 696  GLN   A HB3  1 
ATOM   2841 N N    . VAL   A 1 188 ? 30.833 27.383 53.244 1   78.114 ? 697  VAL   A N    1 
ATOM   2842 C CA   . VAL   A 1 188 ? 30.723 25.949 53.485 1   74.002 ? 697  VAL   A CA   1 
ATOM   2843 C C    . VAL   A 1 188 ? 29.49  25.647 54.342 1   70.814 ? 697  VAL   A C    1 
ATOM   2844 O O    . VAL   A 1 188 ? 28.988 24.526 54.293 1   72.332 ? 697  VAL   A O    1 
ATOM   2845 C CB   . VAL   A 1 188 ? 31.995 25.371 54.138 1   69.85  ? 697  VAL   A CB   1 
ATOM   2846 H H    . VAL   A 1 188 ? 31.503 27.846 53.659 1   75.882 ? 697  VAL   A H    1 
ATOM   2847 H HA   . VAL   A 1 188 ? 30.603 25.51  52.621 1   73.437 ? 697  VAL   A HA   1 
ATOM   2848 H HB   . VAL   A 1 188 ? 31.662 24.771 54.916 0   30     ? 697  VAL   A HB   1 
ATOM   2849 N N    . GLU   A 1 189 ? 29.014 26.64  55.115 1   66.215 ? 698  GLU   A N    1 
ATOM   2850 C CA   . GLU   A 1 189 ? 27.836 26.505 55.966 1   61.584 ? 698  GLU   A CA   1 
ATOM   2851 C C    . GLU   A 1 189 ? 26.573 26.236 55.138 1   63.218 ? 698  GLU   A C    1 
ATOM   2852 O O    . GLU   A 1 189 ? 25.764 25.387 55.507 1   59.621 ? 698  GLU   A O    1 
ATOM   2853 C CB   . GLU   A 1 189 ? 27.691 27.763 56.828 1   55.211 ? 698  GLU   A CB   1 
ATOM   2854 H H    . GLU   A 1 189 ? 29.459 27.438 55.12  1   66.279 ? 698  GLU   A H    1 
ATOM   2855 H HA   . GLU   A 1 189 ? 27.982 25.733 56.57  1   61.518 ? 698  GLU   A HA   1 
ATOM   2856 H HB2  . GLU   A 1 189 ? 28.531 28.075 57.079 0   30     ? 698  GLU   A HB2  1 
ATOM   2857 H HB3  . GLU   A 1 189 ? 26.683 27.927 56.976 0   30     ? 698  GLU   A HB3  1 
ATOM   2858 N N    . LEU   A 1 190 ? 26.422 26.955 54.012 1   67.291 ? 699  LEU   A N    1 
ATOM   2859 C CA   . LEU   A 1 190 ? 25.201 27.001 53.214 1   63.153 ? 699  LEU   A CA   1 
ATOM   2860 C C    . LEU   A 1 190 ? 25.193 25.953 52.099 1   56.568 ? 699  LEU   A C    1 
ATOM   2861 O O    . LEU   A 1 190 ? 24.487 26.122 51.109 1   50.481 ? 699  LEU   A O    1 
ATOM   2862 C CB   . LEU   A 1 190 ? 25.116 28.397 52.593 1   67.858 ? 699  LEU   A CB   1 
ATOM   2863 C CG   . LEU   A 1 190 ? 24.891 29.579 53.541 1   73.055 ? 699  LEU   A CG   1 
ATOM   2864 C CD1  . LEU   A 1 190 ? 25.727 30.783 53.13  1   73.15  ? 699  LEU   A CD1  1 
ATOM   2865 C CD2  . LEU   A 1 190 ? 23.416 29.958 53.558 1   71.961 ? 699  LEU   A CD2  1 
ATOM   2866 H H    . LEU   A 1 190 ? 27.134 27.451 53.726 1   65.368 ? 699  LEU   A H    1 
ATOM   2867 H HA   . LEU   A 1 190 ? 24.422 26.855 53.809 1   63.467 ? 699  LEU   A HA   1 
ATOM   2868 H HB2  . LEU   A 1 190 ? 25.949 28.558 52.092 1   67.757 ? 699  LEU   A HB2  1 
ATOM   2869 H HB3  . LEU   A 1 190 ? 24.386 28.393 51.932 1   67.725 ? 699  LEU   A HB3  1 
ATOM   2870 H HG   . LEU   A 1 190 ? 25.158 29.305 54.456 1   71.862 ? 699  LEU   A HG   1 
ATOM   2871 H HD11 . LEU   A 1 190 ? 26.666 30.588 53.272 1   72.925 ? 699  LEU   A HD11 1 
ATOM   2872 H HD12 . LEU   A 1 190 ? 25.473 31.553 53.667 1   72.973 ? 699  LEU   A HD12 1 
ATOM   2873 H HD13 . LEU   A 1 190 ? 25.575 30.98  52.191 1   72.545 ? 699  LEU   A HD13 1 
ATOM   2874 H HD21 . LEU   A 1 190 ? 22.886 29.193 53.838 1   72.274 ? 699  LEU   A HD21 1 
ATOM   2875 H HD22 . LEU   A 1 190 ? 23.14  30.233 52.667 1   72.249 ? 699  LEU   A HD22 1 
ATOM   2876 H HD23 . LEU   A 1 190 ? 23.276 30.693 54.179 1   72.274 ? 699  LEU   A HD23 1 
ATOM   2877 N N    . SER   A 1 191 ? 25.929 24.85  52.276 1   57.983 ? 700  SER   A N    1 
ATOM   2878 C CA   . SER   A 1 191 ? 26.217 23.929 51.185 1   56.621 ? 700  SER   A CA   1 
ATOM   2879 C C    . SER   A 1 191 ? 24.96  23.207 50.718 1   46.594 ? 700  SER   A C    1 
ATOM   2880 O O    . SER   A 1 191 ? 24.701 23.157 49.522 1   44.848 ? 700  SER   A O    1 
ATOM   2881 C CB   . SER   A 1 191 ? 27.297 22.933 51.569 1   60.301 ? 700  SER   A CB   1 
ATOM   2882 O OG   . SER   A 1 191 ? 28.527 23.601 51.821 1   65.926 ? 700  SER   A OG   1 
ATOM   2883 H H    . SER   A 1 191 ? 26.25  24.654 53.108 1   57.489 ? 700  SER   A H    1 
ATOM   2884 H HA   . SER   A 1 191 ? 26.556 24.466 50.424 1   55.447 ? 700  SER   A HA   1 
ATOM   2885 H HB2  . SER   A 1 191 ? 27.02  22.447 52.369 1   60.715 ? 700  SER   A HB2  1 
ATOM   2886 H HB3  . SER   A 1 191 ? 27.417 22.29  50.845 1   60.646 ? 700  SER   A HB3  1 
ATOM   2887 H HG   . SER   A 1 191 ? 29.094 23.01  52.071 0   30     ? 700  SER   A HG   1 
ATOM   2888 N N    . THR   A 1 192 ? 24.217 22.604 51.655 1   43.258 ? 701  THR   A N    1 
ATOM   2889 C CA   . THR   A 1 192 ? 23.093 21.754 51.296 1   44.899 ? 701  THR   A CA   1 
ATOM   2890 C C    . THR   A 1 192 ? 21.944 22.604 50.739 1   40.133 ? 701  THR   A C    1 
ATOM   2891 O O    . THR   A 1 192 ? 21.072 22.061 50.075 1   35.185 ? 701  THR   A O    1 
ATOM   2892 C CB   . THR   A 1 192 ? 22.625 20.881 52.469 1   47.483 ? 701  THR   A CB   1 
ATOM   2893 O OG1  . THR   A 1 192 ? 22.314 21.738 53.562 1   50.915 ? 701  THR   A OG1  1 
ATOM   2894 C CG2  . THR   A 1 192 ? 23.659 19.868 52.93  1   49.783 ? 701  THR   A CG2  1 
ATOM   2895 H H    . THR   A 1 192 ? 24.417 22.725 52.539 1   44.568 ? 701  THR   A H    1 
ATOM   2896 H HA   . THR   A 1 192 ? 23.396 21.151 50.582 1   44.134 ? 701  THR   A HA   1 
ATOM   2897 H HB   . THR   A 1 192 ? 21.809 20.394 52.201 1   48.067 ? 701  THR   A HB   1 
ATOM   2898 H HG1  . THR   A 1 192 ? 23.033 22.158 53.8   0   30     ? 701  THR   A HG1  1 
ATOM   2899 H HG21 . THR   A 1 192 ? 23.302 19.356 53.675 1   49.092 ? 701  THR   A HG21 1 
ATOM   2900 H HG22 . THR   A 1 192 ? 24.464 20.332 53.214 1   49.092 ? 701  THR   A HG22 1 
ATOM   2901 H HG23 . THR   A 1 192 ? 23.873 19.266 52.198 1   49.092 ? 701  THR   A HG23 1 
ATOM   2902 N N    . MET   A 1 193 ? 21.915 23.913 51.04  1   36.218 ? 702  MET   A N    1 
ATOM   2903 C CA   . MET   A 1 193 ? 20.922 24.804 50.454 1   40.272 ? 702  MET   A CA   1 
ATOM   2904 C C    . MET   A 1 193 ? 21.199 24.972 48.957 1   36.863 ? 702  MET   A C    1 
ATOM   2905 O O    . MET   A 1 193 ? 20.304 24.762 48.145 1   33.181 ? 702  MET   A O    1 
ATOM   2906 C CB   . MET   A 1 193 ? 20.885 26.166 51.163 1   38.652 ? 702  MET   A CB   1 
ATOM   2907 C CG   . MET   A 1 193 ? 20.337 26.096 52.566 1   40.427 ? 702  MET   A CG   1 
ATOM   2908 S SD   . MET   A 1 193 ? 20.003 27.739 53.23  1   45.606 ? 702  MET   A SD   1 
ATOM   2909 C CE   . MET   A 1 193 ? 18.606 28.145 52.181 1   43.591 ? 702  MET   A CE   1 
ATOM   2910 H H    . MET   A 1 193 ? 22.517 24.256 51.636 1   38.136 ? 702  MET   A H    1 
ATOM   2911 H HA   . MET   A 1 193 ? 20.038 24.371 50.551 1   38.517 ? 702  MET   A HA   1 
ATOM   2912 H HB2  . MET   A 1 193 ? 21.795 26.529 51.194 1   39.424 ? 702  MET   A HB2  1 
ATOM   2913 H HB3  . MET   A 1 193 ? 20.334 26.78  50.633 1   39.453 ? 702  MET   A HB3  1 
ATOM   2914 H HG2  . MET   A 1 193 ? 19.509 25.576 52.569 1   40.962 ? 702  MET   A HG2  1 
ATOM   2915 H HG3  . MET   A 1 193 ? 20.982 25.643 53.146 1   40.926 ? 702  MET   A HG3  1 
ATOM   2916 H HE1  . MET   A 1 193 ? 18.063 28.829 52.614 1   43.865 ? 702  MET   A HE1  1 
ATOM   2917 H HE2  . MET   A 1 193 ? 18.929 28.482 51.325 1   43.985 ? 702  MET   A HE2  1 
ATOM   2918 H HE3  . MET   A 1 193 ? 18.066 27.346 52.034 1   43.97  ? 702  MET   A HE3  1 
ATOM   2919 N N    . TYR   A 1 194 ? 22.456 25.297 48.614 1   38.054 ? 703  TYR   A N    1 
ATOM   2920 C CA   . TYR   A 1 194 ? 22.929 25.385 47.239 1   42.939 ? 703  TYR   A CA   1 
ATOM   2921 C C    . TYR   A 1 194 ? 22.604 24.114 46.455 1   41.042 ? 703  TYR   A C    1 
ATOM   2922 O O    . TYR   A 1 194 ? 22.102 24.209 45.34  1   36.803 ? 703  TYR   A O    1 
ATOM   2923 C CB   . TYR   A 1 194 ? 24.433 25.688 47.223 1   50.401 ? 703  TYR   A CB   1 
ATOM   2924 C CG   . TYR   A 1 194 ? 25.154 25.368 45.917 1   61.829 ? 703  TYR   A CG   1 
ATOM   2925 C CD1  . TYR   A 1 194 ? 24.851 26.038 44.732 1   63.43  ? 703  TYR   A CD1  1 
ATOM   2926 C CD2  . TYR   A 1 194 ? 26.157 24.403 45.876 1   66.394 ? 703  TYR   A CD2  1 
ATOM   2927 C CE1  . TYR   A 1 194 ? 25.511 25.742 43.548 1   65.996 ? 703  TYR   A CE1  1 
ATOM   2928 C CE2  . TYR   A 1 194 ? 26.83  24.108 44.7   1   68.903 ? 703  TYR   A CE2  1 
ATOM   2929 C CZ   . TYR   A 1 194 ? 26.509 24.783 43.535 1   70.223 ? 703  TYR   A CZ   1 
ATOM   2930 O OH   . TYR   A 1 194 ? 27.168 24.495 42.375 1   72.542 ? 703  TYR   A OH   1 
ATOM   2931 H H    . TYR   A 1 194 ? 23.049 25.483 49.284 1   38.966 ? 703  TYR   A H    1 
ATOM   2932 H HA   . TYR   A 1 194 ? 22.459 26.144 46.803 1   42.79  ? 703  TYR   A HA   1 
ATOM   2933 H HB2  . TYR   A 1 194 ? 24.556 26.642 47.422 1   50.785 ? 703  TYR   A HB2  1 
ATOM   2934 H HB3  . TYR   A 1 194 ? 24.859 25.181 47.949 1   50.842 ? 703  TYR   A HB3  1 
ATOM   2935 H HD1  . TYR   A 1 194 ? 24.174 26.696 44.731 1   63.658 ? 703  TYR   A HD1  1 
ATOM   2936 H HD2  . TYR   A 1 194 ? 26.387 23.94  46.666 1   65.676 ? 703  TYR   A HD2  1 
ATOM   2937 H HE1  . TYR   A 1 194 ? 25.293 26.204 42.758 1   66.025 ? 703  TYR   A HE1  1 
ATOM   2938 H HE2  . TYR   A 1 194 ? 27.505 23.451 44.693 1   68.5   ? 703  TYR   A HE2  1 
ATOM   2939 H HH   . TYR   A 1 194 ? 26.84  24.941 41.717 0   30     ? 703  TYR   A HH   1 
ATOM   2940 N N    . ARG   A 1 195 ? 22.902 22.941 47.034 1   41.076 ? 704  ARG   A N    1 
ATOM   2941 C CA   . ARG   A 1 195 ? 22.68  21.65  46.392 1   38.34  ? 704  ARG   A CA   1 
ATOM   2942 C C    . ARG   A 1 195 ? 21.187 21.43  46.114 1   38.758 ? 704  ARG   A C    1 
ATOM   2943 O O    . ARG   A 1 195 ? 20.824 20.876 45.073 1   39.245 ? 704  ARG   A O    1 
ATOM   2944 C CB   . ARG   A 1 195 ? 23.316 20.539 47.243 1   35.592 ? 704  ARG   A CB   1 
ATOM   2945 H H    . ARG   A 1 195 ? 23.265 22.95  47.873 1   40.399 ? 704  ARG   A H    1 
ATOM   2946 H HA   . ARG   A 1 195 ? 23.151 21.663 45.52  1   38.409 ? 704  ARG   A HA   1 
ATOM   2947 H HB2  . ARG   A 1 195 ? 24.279 20.604 47.191 0   30     ? 704  ARG   A HB2  1 
ATOM   2948 H HB3  . ARG   A 1 195 ? 22.578 20.011 47.648 0   30     ? 704  ARG   A HB3  1 
ATOM   2949 N N    . HIS   A 1 196 ? 20.321 21.864 47.042 1   40.564 ? 705  HIS   A N    1 
ATOM   2950 C CA   . HIS   A 1 196 ? 18.878 21.731 46.895 1   44.639 ? 705  HIS   A CA   1 
ATOM   2951 C C    . HIS   A 1 196 ? 18.367 22.654 45.785 1   42.409 ? 705  HIS   A C    1 
ATOM   2952 O O    . HIS   A 1 196 ? 17.574 22.234 44.946 1   42.412 ? 705  HIS   A O    1 
ATOM   2953 C CB   . HIS   A 1 196 ? 18.168 22.032 48.221 1   53.927 ? 705  HIS   A CB   1 
ATOM   2954 C CG   . HIS   A 1 196 ? 16.693 21.732 48.221 1   67.622 ? 705  HIS   A CG   1 
ATOM   2955 N ND1  . HIS   A 1 196 ? 15.726 22.653 47.859 1   75.317 ? 705  HIS   A ND1  1 
ATOM   2956 C CD2  . HIS   A 1 196 ? 16.021 20.613 48.548 1   73.253 ? 705  HIS   A CD2  1 
ATOM   2957 C CE1  . HIS   A 1 196 ? 14.525 22.1   47.959 1   75.861 ? 705  HIS   A CE1  1 
ATOM   2958 N NE2  . HIS   A 1 196 ? 14.678 20.862 48.379 1   76.909 ? 705  HIS   A NE2  1 
ATOM   2959 H H    . HIS   A 1 196 ? 20.646 22.253 47.802 1   41.062 ? 705  HIS   A H    1 
ATOM   2960 H HA   . HIS   A 1 196 ? 18.682 20.797 46.636 1   44.861 ? 705  HIS   A HA   1 
ATOM   2961 H HB2  . HIS   A 1 196 ? 18.599 21.513 48.933 1   54.404 ? 705  HIS   A HB2  1 
ATOM   2962 H HB3  . HIS   A 1 196 ? 18.297 22.982 48.435 1   54.306 ? 705  HIS   A HB3  1 
ATOM   2963 H HD1  . HIS   A 1 196 ? 15.882 23.48  47.622 0   30     ? 705  HIS   A HD1  1 
ATOM   2964 H HD2  . HIS   A 1 196 ? 16.386 19.801 48.837 1   72.443 ? 705  HIS   A HD2  1 
ATOM   2965 H HE1  . HIS   A 1 196 ? 13.706 22.522 47.768 1   74.376 ? 705  HIS   A HE1  1 
ATOM   2966 H HE2  . HIS   A 1 196 ? 14.058 20.264 48.512 0   30     ? 705  HIS   A HE2  1 
ATOM   2967 N N    . MET   A 1 197 ? 18.825 23.914 45.802 1   39.226 ? 706  MET   A N    1 
ATOM   2968 C CA   . MET   A 1 197 ? 18.391 24.934 44.855 1   41.326 ? 706  MET   A CA   1 
ATOM   2969 C C    . MET   A 1 197 ? 18.749 24.55  43.419 1   38.211 ? 706  MET   A C    1 
ATOM   2970 O O    . MET   A 1 197 ? 17.934 24.749 42.52  1   36.016 ? 706  MET   A O    1 
ATOM   2971 C CB   . MET   A 1 197 ? 19.03  26.298 45.156 1   39.131 ? 706  MET   A CB   1 
ATOM   2972 C CG   . MET   A 1 197 ? 18.473 26.979 46.388 1   40.4   ? 706  MET   A CG   1 
ATOM   2973 S SD   . MET   A 1 197 ? 18.927 28.721 46.469 1   44.723 ? 706  MET   A SD   1 
ATOM   2974 C CE   . MET   A 1 197 ? 20.709 28.638 46.662 1   51.337 ? 706  MET   A CE   1 
ATOM   2975 H H    . MET   A 1 197 ? 19.436 24.149 46.439 1   40.455 ? 706  MET   A H    1 
ATOM   2976 H HA   . MET   A 1 197 ? 17.405 25.014 44.92  1   39.934 ? 706  MET   A HA   1 
ATOM   2977 H HB2  . MET   A 1 197 ? 19.996 26.172 45.271 1   39.962 ? 706  MET   A HB2  1 
ATOM   2978 H HB3  . MET   A 1 197 ? 18.896 26.885 44.381 1   39.909 ? 706  MET   A HB3  1 
ATOM   2979 H HG2  . MET   A 1 197 ? 17.498 26.907 46.387 1   40.848 ? 706  MET   A HG2  1 
ATOM   2980 H HG3  . MET   A 1 197 ? 18.807 26.529 47.187 1   40.773 ? 706  MET   A HG3  1 
ATOM   2981 H HE1  . MET   A 1 197 ? 21.071 29.54  46.732 1   49.544 ? 706  MET   A HE1  1 
ATOM   2982 H HE2  . MET   A 1 197 ? 20.925 28.137 47.47  1   49.544 ? 706  MET   A HE2  1 
ATOM   2983 H HE3  . MET   A 1 197 ? 21.099 28.19  45.888 1   49.385 ? 706  MET   A HE3  1 
ATOM   2984 N N    . GLU   A 1 198 ? 19.975 24.056 43.204 1   35.758 ? 707  GLU   A N    1 
ATOM   2985 C CA   . GLU   A 1 198 ? 20.457 23.694 41.872 1   42.671 ? 707  GLU   A CA   1 
ATOM   2986 C C    . GLU   A 1 198 ? 19.454 22.777 41.156 1   45.058 ? 707  GLU   A C    1 
ATOM   2987 O O    . GLU   A 1 198 ? 19.294 22.877 39.94  1   51.08  ? 707  GLU   A O    1 
ATOM   2988 C CB   . GLU   A 1 198 ? 21.843 23.043 41.945 1   42.076 ? 707  GLU   A CB   1 
ATOM   2989 H H    . GLU   A 1 198 ? 20.537 23.945 43.916 1   37.861 ? 707  GLU   A H    1 
ATOM   2990 H HA   . GLU   A 1 198 ? 20.541 24.528 41.344 1   41.525 ? 707  GLU   A HA   1 
ATOM   2991 H HB2  . GLU   A 1 198 ? 22.514 23.744 41.846 0   30     ? 707  GLU   A HB2  1 
ATOM   2992 H HB3  . GLU   A 1 198 ? 21.716 22.08  42.047 0   30     ? 707  GLU   A HB3  1 
ATOM   2993 N N    . LYS   A 1 199 ? 18.758 21.917 41.922 1   40.117 ? 708  LYS   A N    1 
ATOM   2994 C CA   . LYS   A 1 199 ? 17.789 20.964 41.395 1   41.729 ? 708  LYS   A CA   1 
ATOM   2995 C C    . LYS   A 1 199 ? 16.55  21.659 40.822 1   40.744 ? 708  LYS   A C    1 
ATOM   2996 O O    . LYS   A 1 199 ? 15.914 21.107 39.928 1   47.758 ? 708  LYS   A O    1 
ATOM   2997 C CB   . LYS   A 1 199 ? 17.351 19.98  42.494 1   41.167 ? 708  LYS   A CB   1 
ATOM   2998 H H    . LYS   A 1 199 ? 18.913 21.917 42.823 1   41.549 ? 708  LYS   A H    1 
ATOM   2999 H HA   . LYS   A 1 199 ? 18.225 20.45  40.668 1   41.127 ? 708  LYS   A HA   1 
ATOM   3000 H HB2  . LYS   A 1 199 ? 18.155 19.584 42.874 0   30     ? 708  LYS   A HB2  1 
ATOM   3001 H HB3  . LYS   A 1 199 ? 16.371 19.937 42.49  0   30     ? 708  LYS   A HB3  1 
ATOM   3002 N N    . HIS   A 1 200 ? 16.2   22.852 41.333 1   34.938 ? 709  HIS   A N    1 
ATOM   3003 C CA   . HIS   A 1 200 ? 14.881 23.436 41.114 1   33.477 ? 709  HIS   A CA   1 
ATOM   3004 C C    . HIS   A 1 200 ? 14.928 24.868 40.575 1   27.532 ? 709  HIS   A C    1 
ATOM   3005 O O    . HIS   A 1 200 ? 13.904 25.547 40.617 1   27.861 ? 709  HIS   A O    1 
ATOM   3006 C CB   . HIS   A 1 200 ? 14.134 23.544 42.459 1   35.912 ? 709  HIS   A CB   1 
ATOM   3007 C CG   . HIS   A 1 200 ? 13.891 22.244 43.133 1   37.455 ? 709  HIS   A CG   1 
ATOM   3008 N ND1  . HIS   A 1 200 ? 13.174 21.238 42.524 1   37.939 ? 709  HIS   A ND1  1 
ATOM   3009 C CD2  . HIS   A 1 200 ? 14.21  21.802 44.362 1   41.017 ? 709  HIS   A CD2  1 
ATOM   3010 C CE1  . HIS   A 1 200 ? 13.095 20.205 43.358 1   39.737 ? 709  HIS   A CE1  1 
ATOM   3011 N NE2  . HIS   A 1 200 ? 13.71  20.532 44.481 1   38.778 ? 709  HIS   A NE2  1 
ATOM   3012 H H    . HIS   A 1 200 ? 16.802 23.316 41.84  1   36.018 ? 709  HIS   A H    1 
ATOM   3013 H HA   . HIS   A 1 200 ? 14.363 22.876 40.485 1   33.087 ? 709  HIS   A HA   1 
ATOM   3014 H HB2  . HIS   A 1 200 ? 14.654 24.121 43.06  1   35.631 ? 709  HIS   A HB2  1 
ATOM   3015 H HB3  . HIS   A 1 200 ? 13.269 23.982 42.304 1   35.585 ? 709  HIS   A HB3  1 
ATOM   3016 H HD1  . HIS   A 1 200 ? 12.813 21.267 41.737 0   30     ? 709  HIS   A HD1  1 
ATOM   3017 H HD2  . HIS   A 1 200 ? 14.693 22.266 45.017 1   39.631 ? 709  HIS   A HD2  1 
ATOM   3018 H HE1  . HIS   A 1 200 ? 12.664 19.386 43.181 1   39.086 ? 709  HIS   A HE1  1 
ATOM   3019 H HE2  . HIS   A 1 200 ? 13.832 19.994 45.185 0   30     ? 709  HIS   A HE2  1 
ATOM   3020 N N    . ASN   A 1 201 ? 16.083 25.358 40.107 1   23.448 ? 710  ASN   A N    1 
ATOM   3021 C CA   . ASN   A 1 201 ? 16.205 26.783 39.819 1   19.794 ? 710  ASN   A CA   1 
ATOM   3022 C C    . ASN   A 1 201 ? 15.463 27.156 38.534 1   19.873 ? 710  ASN   A C    1 
ATOM   3023 O O    . ASN   A 1 201 ? 15.237 26.318 37.664 1   18.827 ? 710  ASN   A O    1 
ATOM   3024 C CB   . ASN   A 1 201 ? 17.659 27.223 39.758 1   18.19  ? 710  ASN   A CB   1 
ATOM   3025 C CG   . ASN   A 1 201 ? 18.264 27.444 41.113 1   17.647 ? 710  ASN   A CG   1 
ATOM   3026 O OD1  . ASN   A 1 201 ? 17.569 27.658 42.12  1   15.156 ? 710  ASN   A OD1  1 
ATOM   3027 N ND2  . ASN   A 1 201 ? 19.586 27.457 41.131 1   19.873 ? 710  ASN   A ND2  1 
ATOM   3028 H H    . ASN   A 1 201 ? 16.796 24.806 39.957 1   23.444 ? 710  ASN   A H    1 
ATOM   3029 H HA   . ASN   A 1 201 ? 15.783 27.276 40.558 1   20.126 ? 710  ASN   A HA   1 
ATOM   3030 H HB2  . ASN   A 1 201 ? 18.179 26.543 39.285 1   18.453 ? 710  ASN   A HB2  1 
ATOM   3031 H HB3  . ASN   A 1 201 ? 17.72  28.055 39.246 1   18.429 ? 710  ASN   A HB3  1 
ATOM   3032 H HD21 . ASN   A 1 201 ? 20.022 27.115 41.824 1   19.157 ? 710  ASN   A HD21 1 
ATOM   3033 H HD22 . ASN   A 1 201 ? 20.036 27.809 40.451 1   19.152 ? 710  ASN   A HD22 1 
ATOM   3034 N N    . TYR   A 1 202 ? 15.075 28.442 38.412 1   19.379 ? 711  TYR   A N    1 
ATOM   3035 C CA   . TYR   A 1 202 ? 14.236 28.885 37.319 1   16.982 ? 711  TYR   A CA   1 
ATOM   3036 C C    . TYR   A 1 202 ? 15.053 29.625 36.269 1   16.913 ? 711  TYR   A C    1 
ATOM   3037 O O    . TYR   A 1 202 ? 16.135 30.154 36.532 1   16.732 ? 711  TYR   A O    1 
ATOM   3038 C CB   . TYR   A 1 202 ? 13.105 29.736 37.907 1   18.873 ? 711  TYR   A CB   1 
ATOM   3039 C CG   . TYR   A 1 202 ? 11.981 28.897 38.5   1   17.765 ? 711  TYR   A CG   1 
ATOM   3040 C CD1  . TYR   A 1 202 ? 12.113 28.297 39.743 1   17.964 ? 711  TYR   A CD1  1 
ATOM   3041 C CD2  . TYR   A 1 202 ? 10.789 28.691 37.803 1   18.221 ? 711  TYR   A CD2  1 
ATOM   3042 C CE1  . TYR   A 1 202 ? 11.095 27.528 40.287 1   17.434 ? 711  TYR   A CE1  1 
ATOM   3043 C CE2  . TYR   A 1 202 ? 9.773  27.919 38.333 1   19.336 ? 711  TYR   A CE2  1 
ATOM   3044 C CZ   . TYR   A 1 202 ? 9.942  27.315 39.565 1   17.996 ? 711  TYR   A CZ   1 
ATOM   3045 O OH   . TYR   A 1 202 ? 8.904  26.599 40.065 1   21.584 ? 711  TYR   A OH   1 
ATOM   3046 H H    . TYR   A 1 202 ? 15.35  29.054 39.033 1   18.929 ? 711  TYR   A H    1 
ATOM   3047 H HA   . TYR   A 1 202 ? 13.831 28.086 36.891 1   17.816 ? 711  TYR   A HA   1 
ATOM   3048 H HB2  . TYR   A 1 202 ? 13.476 30.317 38.607 1   18.186 ? 711  TYR   A HB2  1 
ATOM   3049 H HB3  . TYR   A 1 202 ? 12.738 30.307 37.196 1   18.17  ? 711  TYR   A HB3  1 
ATOM   3050 H HD1  . TYR   A 1 202 ? 12.91  28.419 40.234 1   17.817 ? 711  TYR   A HD1  1 
ATOM   3051 H HD2  . TYR   A 1 202 ? 10.677 29.081 36.95  1   18.372 ? 711  TYR   A HD2  1 
ATOM   3052 H HE1  . TYR   A 1 202 ? 11.203 27.126 41.132 1   17.723 ? 711  TYR   A HE1  1 
ATOM   3053 H HE2  . TYR   A 1 202 ? 8.975  27.79  37.849 1   18.754 ? 711  TYR   A HE2  1 
ATOM   3054 H HH   . TYR   A 1 202 ? 9.101  26.324 40.866 0   30     ? 711  TYR   A HH   1 
ATOM   3055 N N    . GLU   A 1 203 ? 14.491 29.662 35.06  1   16.581 ? 712  GLU   A N    1 
ATOM   3056 C CA   . GLU   A 1 203 ? 15.135 30.309 33.931 1   17.828 ? 712  GLU   A CA   1 
ATOM   3057 C C    . GLU   A 1 203 ? 15.048 31.835 34.079 1   15.098 ? 712  GLU   A C    1 
ATOM   3058 O O    . GLU   A 1 203 ? 15.915 32.539 33.596 1   13.894 ? 712  GLU   A O    1 
ATOM   3059 C CB   . GLU   A 1 203 ? 14.468 29.8   32.652 1   21.365 ? 712  GLU   A CB   1 
ATOM   3060 C CG   . GLU   A 1 203 ? 14.71  28.303 32.418 1   25.031 ? 712  GLU   A CG   1 
ATOM   3061 C CD   . GLU   A 1 203 ? 16.156 27.962 32.064 1   27.425 ? 712  GLU   A CD   1 
ATOM   3062 O OE1  . GLU   A 1 203 ? 16.949 28.877 31.724 1   26.511 ? 712  GLU   A OE1  1 
ATOM   3063 O OE2  . GLU   A 1 203 ? 16.482 26.77  32.127 1   26.134 ? 712  GLU   A OE2  1 
ATOM   3064 H H    . GLU   A 1 203 ? 13.674 29.273 34.936 1   17.081 ? 712  GLU   A H    1 
ATOM   3065 H HA   . GLU   A 1 203 ? 16.09  30.047 33.924 1   17.69  ? 712  GLU   A HA   1 
ATOM   3066 H HB2  . GLU   A 1 203 ? 13.504 29.964 32.71  1   21.279 ? 712  GLU   A HB2  1 
ATOM   3067 H HB3  . GLU   A 1 203 ? 14.812 30.31  31.889 1   21.278 ? 712  GLU   A HB3  1 
ATOM   3068 H HG2  . GLU   A 1 203 ? 14.463 27.806 33.226 1   24.584 ? 712  GLU   A HG2  1 
ATOM   3069 H HG3  . GLU   A 1 203 ? 14.129 27.994 31.69  1   24.645 ? 712  GLU   A HG3  1 
ATOM   3070 N N    . SER   A 1 204 ? 14.016 32.331 34.764 1   13.128 ? 713  SER   A N    1 
ATOM   3071 C CA   . SER   A 1 204 ? 13.818 33.761 34.945 1   14.071 ? 713  SER   A CA   1 
ATOM   3072 C C    . SER   A 1 204 ? 13.102 34.034 36.269 1   13.48  ? 713  SER   A C    1 
ATOM   3073 O O    . SER   A 1 204 ? 12.405 33.166 36.806 1   13.768 ? 713  SER   A O    1 
ATOM   3074 C CB   . SER   A 1 204 ? 13.065 34.379 33.803 1   13.733 ? 713  SER   A CB   1 
ATOM   3075 O OG   . SER   A 1 204 ? 11.712 33.963 33.805 1   12.748 ? 713  SER   A OG   1 
ATOM   3076 H H    . SER   A 1 204 ? 13.403 31.758 35.126 1   13.842 ? 713  SER   A H    1 
ATOM   3077 H HA   . SER   A 1 204 ? 14.711 34.188 34.991 1   13.716 ? 713  SER   A HA   1 
ATOM   3078 H HB2  . SER   A 1 204 ? 13.107 35.351 33.877 1   13.567 ? 713  SER   A HB2  1 
ATOM   3079 H HB3  . SER   A 1 204 ? 13.484 34.117 32.961 1   13.567 ? 713  SER   A HB3  1 
ATOM   3080 H HG   . SER   A 1 204 ? 11.319 34.328 33.155 0   30     ? 713  SER   A HG   1 
ATOM   3081 N N    . ALA   A 1 205 ? 13.33  35.24  36.804 1   12.53  ? 714  ALA   A N    1 
ATOM   3082 C CA   . ALA   A 1 205 ? 12.65  35.716 38.01  1   11.897 ? 714  ALA   A CA   1 
ATOM   3083 C C    . ALA   A 1 205 ? 11.143 35.687 37.813 1   11.867 ? 714  ALA   A C    1 
ATOM   3084 O O    . ALA   A 1 205 ? 10.392 35.293 38.716 1   11.092 ? 714  ALA   A O    1 
ATOM   3085 C CB   . ALA   A 1 205 ? 13.125 37.102 38.374 1   11.491 ? 714  ALA   A CB   1 
ATOM   3086 H H    . ALA   A 1 205 ? 13.935 35.793 36.4   1   12.613 ? 714  ALA   A H    1 
ATOM   3087 H HA   . ALA   A 1 205 ? 12.875 35.093 38.755 1   11.936 ? 714  ALA   A HA   1 
ATOM   3088 H HB1  . ALA   A 1 205 ? 14.082 37.087 38.541 1   11.61  ? 714  ALA   A HB1  1 
ATOM   3089 H HB2  . ALA   A 1 205 ? 12.936 37.715 37.644 1   11.61  ? 714  ALA   A HB2  1 
ATOM   3090 H HB3  . ALA   A 1 205 ? 12.664 37.406 39.174 1   11.61  ? 714  ALA   A HB3  1 
ATOM   3091 N N    . ALA   A 1 206 ? 10.686 36.173 36.651 1   12.736 ? 715  ALA   A N    1 
ATOM   3092 C CA   . ALA   A 1 206 ? 9.25   36.222 36.409 1   13.579 ? 715  ALA   A CA   1 
ATOM   3093 C C    . ALA   A 1 206 ? 8.622  34.831 36.549 1   14.208 ? 715  ALA   A C    1 
ATOM   3094 O O    . ALA   A 1 206 ? 7.526  34.677 37.108 1   13.079 ? 715  ALA   A O    1 
ATOM   3095 C CB   . ALA   A 1 206 ? 8.95   36.818 35.054 1   14.169 ? 715  ALA   A CB   1 
ATOM   3096 H H    . ALA   A 1 206 ? 11.264 36.479 36.012 1   12.706 ? 715  ALA   A H    1 
ATOM   3097 H HA   . ALA   A 1 206 ? 8.846  36.807 37.107 1   13.614 ? 715  ALA   A HA   1 
ATOM   3098 H HB1  . ALA   A 1 206 ? 9.303  37.723 35.009 1   13.991 ? 715  ALA   A HB1  1 
ATOM   3099 H HB2  . ALA   A 1 206 ? 9.364  36.278 34.36  1   13.991 ? 715  ALA   A HB2  1 
ATOM   3100 H HB3  . ALA   A 1 206 ? 7.989  36.841 34.913 1   13.991 ? 715  ALA   A HB3  1 
ATOM   3101 N N    . GLU   A 1 207 ? 9.299  33.793 36.045 1   16.132 ? 716  GLU   A N    1 
ATOM   3102 C CA   . GLU   A 1 207 ? 8.734  32.448 36.148 1   16.691 ? 716  GLU   A CA   1 
ATOM   3103 C C    . GLU   A 1 207 ? 8.708  31.97  37.595 1   14.857 ? 716  GLU   A C    1 
ATOM   3104 O O    . GLU   A 1 207 ? 7.744  31.339 38.018 1   14.429 ? 716  GLU   A O    1 
ATOM   3105 C CB   . GLU   A 1 207 ? 9.535  31.445 35.319 1   20.52  ? 716  GLU   A CB   1 
ATOM   3106 C CG   . GLU   A 1 207 ? 9.291  31.574 33.824 1   25.762 ? 716  GLU   A CG   1 
ATOM   3107 C CD   . GLU   A 1 207 ? 10.455 30.995 33.021 1   31.268 ? 716  GLU   A CD   1 
ATOM   3108 O OE1  . GLU   A 1 207 ? 10.855 29.84  33.266 1   35.327 ? 716  GLU   A OE1  1 
ATOM   3109 O OE2  . GLU   A 1 207 ? 10.995 31.755 32.2   1   33.746 ? 716  GLU   A OE2  1 
ATOM   3110 H H    . GLU   A 1 207 ? 10.106 33.915 35.633 1   15.791 ? 716  GLU   A H    1 
ATOM   3111 H HA   . GLU   A 1 207 ? 7.804  32.471 35.805 1   16.82  ? 716  GLU   A HA   1 
ATOM   3112 H HB2  . GLU   A 1 207 ? 10.489 31.576 35.503 1   20.64  ? 716  GLU   A HB2  1 
ATOM   3113 H HB3  . GLU   A 1 207 ? 9.298  30.538 35.603 1   20.653 ? 716  GLU   A HB3  1 
ATOM   3114 H HG2  . GLU   A 1 207 ? 8.468  31.097 33.584 1   25.559 ? 716  GLU   A HG2  1 
ATOM   3115 H HG3  . GLU   A 1 207 ? 9.179  32.521 33.59  1   25.546 ? 716  GLU   A HG3  1 
ATOM   3116 N N    . ALA   A 1 208 ? 9.793  32.229 38.351 1   13.774 ? 717  ALA   A N    1 
ATOM   3117 C CA   . ALA   A 1 208 ? 9.842  31.858 39.754 1   13.074 ? 717  ALA   A CA   1 
ATOM   3118 C C    . ALA   A 1 208 ? 8.703  32.535 40.518 1   13.366 ? 717  ALA   A C    1 
ATOM   3119 O O    . ALA   A 1 208 ? 8.006  31.892 41.32  1   11.765 ? 717  ALA   A O    1 
ATOM   3120 C CB   . ALA   A 1 208 ? 11.189 32.207 40.344 1   13.519 ? 717  ALA   A CB   1 
ATOM   3121 H H    . ALA   A 1 208 ? 10.518 32.641 37.977 1   13.889 ? 717  ALA   A H    1 
ATOM   3122 H HA   . ALA   A 1 208 ? 9.71   30.871 39.815 1   13.348 ? 717  ALA   A HA   1 
ATOM   3123 H HB1  . ALA   A 1 208 ? 11.888 31.728 39.869 1   13.386 ? 717  ALA   A HB1  1 
ATOM   3124 H HB2  . ALA   A 1 208 ? 11.343 33.163 40.264 1   13.386 ? 717  ALA   A HB2  1 
ATOM   3125 H HB3  . ALA   A 1 208 ? 11.209 31.957 41.283 1   13.386 ? 717  ALA   A HB3  1 
ATOM   3126 N N    . ILE   A 1 209 ? 8.539  33.843 40.289 1   13.001 ? 718  ILE   A N    1 
ATOM   3127 C CA   . ILE   A 1 209 ? 7.54   34.623 41.016 1   12.654 ? 718  ILE   A CA   1 
ATOM   3128 C C    . ILE   A 1 209 ? 6.157  34.025 40.769 1   12.977 ? 718  ILE   A C    1 
ATOM   3129 O O    . ILE   A 1 209 ? 5.393  33.822 41.711 1   12.392 ? 718  ILE   A O    1 
ATOM   3130 C CB   . ILE   A 1 209 ? 7.608  36.113 40.651 1   12.884 ? 718  ILE   A CB   1 
ATOM   3131 C CG1  . ILE   A 1 209 ? 8.911  36.734 41.135 1   12.548 ? 718  ILE   A CG1  1 
ATOM   3132 C CG2  . ILE   A 1 209 ? 6.383  36.883 41.183 1   13.126 ? 718  ILE   A CG2  1 
ATOM   3133 C CD1  . ILE   A 1 209 ? 9.376  37.944 40.343 1   13.516 ? 718  ILE   A CD1  1 
ATOM   3134 H H    . ILE   A 1 209 ? 9.061  34.264 39.668 1   13.009 ? 718  ILE   A H    1 
ATOM   3135 H HA   . ILE   A 1 209 ? 7.736  34.541 41.97  1   12.82  ? 718  ILE   A HA   1 
ATOM   3136 H HB   . ILE   A 1 209 ? 7.598  36.177 39.675 1   12.825 ? 718  ILE   A HB   1 
ATOM   3137 H HG12 . ILE   A 1 209 ? 8.798  37     42.071 1   12.841 ? 718  ILE   A HG12 1 
ATOM   3138 H HG13 . ILE   A 1 209 ? 9.614  36.054 41.105 1   12.832 ? 718  ILE   A HG13 1 
ATOM   3139 H HG21 . ILE   A 1 209 ? 6.589  37.832 41.227 1   13.066 ? 718  ILE   A HG21 1 
ATOM   3140 H HG22 . ILE   A 1 209 ? 6.156  36.562 42.072 1   13.068 ? 718  ILE   A HG22 1 
ATOM   3141 H HG23 . ILE   A 1 209 ? 5.627  36.746 40.587 1   13.112 ? 718  ILE   A HG23 1 
ATOM   3142 H HD11 . ILE   A 1 209 ? 9.684  37.664 39.461 1   13.21  ? 718  ILE   A HD11 1 
ATOM   3143 H HD12 . ILE   A 1 209 ? 10.107 38.384 40.817 1   13.22  ? 718  ILE   A HD12 1 
ATOM   3144 H HD13 . ILE   A 1 209 ? 8.634  38.571 40.242 1   13.218 ? 718  ILE   A HD13 1 
ATOM   3145 N N    . GLN   A 1 210 ? 5.867  33.75  39.493 1   14.415 ? 719  GLN   A N    1 
ATOM   3146 C CA   . GLN   A 1 210 ? 4.599  33.164 39.074 1   16.154 ? 719  GLN   A CA   1 
ATOM   3147 C C    . GLN   A 1 210 ? 4.397  31.825 39.796 1   14.842 ? 719  GLN   A C    1 
ATOM   3148 O O    . GLN   A 1 210 ? 3.287  31.503 40.208 1   15.807 ? 719  GLN   A O    1 
ATOM   3149 C CB   . GLN   A 1 210 ? 4.563  33.071 37.545 1   16.204 ? 719  GLN   A CB   1 
ATOM   3150 C CG   . GLN   A 1 210 ? 3.233  32.6   36.968 1   18.051 ? 719  GLN   A CG   1 
ATOM   3151 C CD   . GLN   A 1 210 ? 2.09   33.56  37.229 1   19.103 ? 719  GLN   A CD   1 
ATOM   3152 O OE1  . GLN   A 1 210 ? 2.17   34.752 36.931 1   22.5   ? 719  GLN   A OE1  1 
ATOM   3153 N NE2  . GLN   A 1 210 ? 1.006  33.063 37.79  1   20.094 ? 719  GLN   A NE2  1 
ATOM   3154 H H    . GLN   A 1 210 ? 6.488  33.942 38.85  1   14.428 ? 719  GLN   A H    1 
ATOM   3155 H HA   . GLN   A 1 210 ? 3.875  33.777 39.36  1   15.58  ? 719  GLN   A HA   1 
ATOM   3156 H HB2  . GLN   A 1 210 ? 4.772  33.954 37.175 1   16.582 ? 719  GLN   A HB2  1 
ATOM   3157 H HB3  . GLN   A 1 210 ? 5.267  32.455 37.255 1   16.594 ? 719  GLN   A HB3  1 
ATOM   3158 H HG2  . GLN   A 1 210 ? 3.327  32.483 35.999 1   17.847 ? 719  GLN   A HG2  1 
ATOM   3159 H HG3  . GLN   A 1 210 ? 3.004  31.727 37.352 1   17.855 ? 719  GLN   A HG3  1 
ATOM   3160 H HE21 . GLN   A 1 210 ? 0.6    33.509 38.441 1   19.78  ? 719  GLN   A HE21 1 
ATOM   3161 H HE22 . GLN   A 1 210 ? 0.683  32.284 37.516 1   19.768 ? 719  GLN   A HE22 1 
ATOM   3162 N N    . ALA   A 1 211 ? 5.474  31.051 39.938 1   13.095 ? 720  ALA   A N    1 
ATOM   3163 C CA   . ALA   A 1 211 ? 5.444  29.757 40.6   1   13.363 ? 720  ALA   A CA   1 
ATOM   3164 C C    . ALA   A 1 211 ? 5.092  29.889 42.079 1   14.743 ? 720  ALA   A C    1 
ATOM   3165 O O    . ALA   A 1 211 ? 4.425  29.01  42.644 1   15.479 ? 720  ALA   A O    1 
ATOM   3166 C CB   . ALA   A 1 211 ? 6.775  29.079 40.417 1   13.136 ? 720  ALA   A CB   1 
ATOM   3167 H H    . ALA   A 1 211 ? 6.27   31.343 39.596 1   13.566 ? 720  ALA   A H    1 
ATOM   3168 H HA   . ALA   A 1 211 ? 4.738  29.205 40.165 1   13.604 ? 720  ALA   A HA   1 
ATOM   3169 H HB1  . ALA   A 1 211 ? 7.073  29.183 39.498 1   13.211 ? 720  ALA   A HB1  1 
ATOM   3170 H HB2  . ALA   A 1 211 ? 7.431  29.476 41.014 1   13.204 ? 720  ALA   A HB2  1 
ATOM   3171 H HB3  . ALA   A 1 211 ? 6.69   28.132 40.62  1   13.205 ? 720  ALA   A HB3  1 
ATOM   3172 N N    . VAL   A 1 212 ? 5.576  30.949 42.728 1   14.191 ? 721  VAL   A N    1 
ATOM   3173 C CA   . VAL   A 1 212 ? 5.194  31.191 44.114 1   15.574 ? 721  VAL   A CA   1 
ATOM   3174 C C    . VAL   A 1 212 ? 3.698  31.514 44.172 1   16.204 ? 721  VAL   A C    1 
ATOM   3175 O O    . VAL   A 1 212 ? 2.993  31.023 45.049 1   18.144 ? 721  VAL   A O    1 
ATOM   3176 C CB   . VAL   A 1 212 ? 6.026  32.28  44.813 1   16.147 ? 721  VAL   A CB   1 
ATOM   3177 C CG1  . VAL   A 1 212 ? 5.526  32.518 46.243 1   16.768 ? 721  VAL   A CG1  1 
ATOM   3178 C CG2  . VAL   A 1 212 ? 7.518  31.947 44.821 1   15.695 ? 721  VAL   A CG2  1 
ATOM   3179 H H    . VAL   A 1 212 ? 6.151  31.525 42.313 1   14.608 ? 721  VAL   A H    1 
ATOM   3180 H HA   . VAL   A 1 212 ? 5.333  30.36  44.602 1   15.523 ? 721  VAL   A HA   1 
ATOM   3181 H HB   . VAL   A 1 212 ? 5.902  33.115 44.304 1   16.066 ? 721  VAL   A HB   1 
ATOM   3182 H HG11 . VAL   A 1 212 ? 5.289  31.668 46.65  1   16.585 ? 721  VAL   A HG11 1 
ATOM   3183 H HG12 . VAL   A 1 212 ? 4.744  33.095 46.223 1   16.576 ? 721  VAL   A HG12 1 
ATOM   3184 H HG13 . VAL   A 1 212 ? 6.226  32.942 46.766 1   16.553 ? 721  VAL   A HG13 1 
ATOM   3185 H HG21 . VAL   A 1 212 ? 8.005  32.646 45.289 1   15.821 ? 721  VAL   A HG21 1 
ATOM   3186 H HG22 . VAL   A 1 212 ? 7.842  31.884 43.908 1   15.783 ? 721  VAL   A HG22 1 
ATOM   3187 H HG23 . VAL   A 1 212 ? 7.659  31.098 45.273 1   15.817 ? 721  VAL   A HG23 1 
ATOM   3188 N N    . ARG   A 1 213 ? 3.218  32.373 43.267 1   16.783 ? 722  ARG   A N    1 
ATOM   3189 C CA   . ARG   A 1 213 ? 1.802  32.709 43.212 1   19.377 ? 722  ARG   A CA   1 
ATOM   3190 C C    . ARG   A 1 213 ? 0.909  31.477 43.016 1   19.156 ? 722  ARG   A C    1 
ATOM   3191 O O    . ARG   A 1 213 ? -0.135 31.356 43.64  1   16.316 ? 722  ARG   A O    1 
ATOM   3192 C CB   . ARG   A 1 213 ? 1.503  33.495 41.949 1   21.624 ? 722  ARG   A CB   1 
ATOM   3193 C CG   . ARG   A 1 213 ? 1.76   34.977 42.024 1   26.2   ? 722  ARG   A CG   1 
ATOM   3194 C CD   . ARG   A 1 213 ? 0.592  35.53  41.161 1   26.824 ? 722  ARG   A CD   1 
ATOM   3195 N NE   . ARG   A 1 213 ? 0.006  36.683 41.846 1   22.558 ? 722  ARG   A NE   1 
ATOM   3196 C CZ   . ARG   A 1 213 ? -0.223 37.857 41.293 1   21.446 ? 722  ARG   A CZ   1 
ATOM   3197 N NH1  . ARG   A 1 213 ? -0.11  37.993 39.983 1   20.444 ? 722  ARG   A NH1  1 
ATOM   3198 N NH2  . ARG   A 1 213 ? -0.619 38.838 42.071 1   20.825 ? 722  ARG   A NH2  1 
ATOM   3199 H H    . ARG   A 1 213 ? 3.789  32.768 42.673 1   17.219 ? 722  ARG   A H    1 
ATOM   3200 H HA   . ARG   A 1 213 ? 1.54   33.202 44.03  1   19.213 ? 722  ARG   A HA   1 
ATOM   3201 H HB2  . ARG   A 1 213 ? 2.042  33.126 41.219 1   21.931 ? 722  ARG   A HB2  1 
ATOM   3202 H HB3  . ARG   A 1 213 ? 0.561  33.349 41.718 1   22.057 ? 722  ARG   A HB3  1 
ATOM   3203 H HG2  . ARG   A 1 213 ? 1.692  35.301 42.949 1   25.127 ? 722  ARG   A HG2  1 
ATOM   3204 H HG3  . ARG   A 1 213 ? 2.625  35.206 41.62  1   25.189 ? 722  ARG   A HG3  1 
ATOM   3205 H HD2  . ARG   A 1 213 ? 0.938  35.805 40.291 1   25.59  ? 722  ARG   A HD2  1 
ATOM   3206 H HD3  . ARG   A 1 213 ? -0.101 34.854 41.017 1   25.537 ? 722  ARG   A HD3  1 
ATOM   3207 H HE   . ARG   A 1 213 ? -0.214 36.585 42.68  1   23.152 ? 722  ARG   A HE   1 
ATOM   3208 H HH11 . ARG   A 1 213 ? -0.584 37.475 39.446 1   20.772 ? 722  ARG   A HH11 1 
ATOM   3209 H HH12 . ARG   A 1 213 ? 0.435  38.602 39.649 1   20.731 ? 722  ARG   A HH12 1 
ATOM   3210 H HH21 . ARG   A 1 213 ? -1.211 38.681 42.709 1   21.046 ? 722  ARG   A HH21 1 
ATOM   3211 H HH22 . ARG   A 1 213 ? -0.3   39.644 41.953 1   21.037 ? 722  ARG   A HH22 1 
ATOM   3212 N N    . ASP   A 1 214 ? 1.352  30.577 42.14  1   19.016 ? 723  ASP   A N    1 
ATOM   3213 C CA   . ASP   A 1 214 ? 0.623  29.378 41.766 1   21.686 ? 723  ASP   A CA   1 
ATOM   3214 C C    . ASP   A 1 214 ? 0.855  28.214 42.732 1   22.604 ? 723  ASP   A C    1 
ATOM   3215 O O    . ASP   A 1 214 ? 0.375  27.118 42.478 1   24.944 ? 723  ASP   A O    1 
ATOM   3216 C CB   . ASP   A 1 214 ? 1.042  28.942 40.372 1   22.188 ? 723  ASP   A CB   1 
ATOM   3217 C CG   . ASP   A 1 214 ? 0.606  29.894 39.281 1   24.43  ? 723  ASP   A CG   1 
ATOM   3218 O OD1  . ASP   A 1 214 ? -0.216 30.76  39.59  1   30.478 ? 723  ASP   A OD1  1 
ATOM   3219 O OD2  . ASP   A 1 214 ? 1.119  29.78  38.16  1   26.724 ? 723  ASP   A OD2  1 
ATOM   3220 H H    . ASP   A 1 214 ? 2.165  30.721 41.748 1   19.652 ? 723  ASP   A H    1 
ATOM   3221 H HA   . ASP   A 1 214 ? -0.338 29.588 41.753 1   21.39  ? 723  ASP   A HA   1 
ATOM   3222 H HB2  . ASP   A 1 214 ? 2.018  28.859 40.341 1   22.551 ? 723  ASP   A HB2  1 
ATOM   3223 H HB3  . ASP   A 1 214 ? 0.656  28.063 40.174 1   22.581 ? 723  ASP   A HB3  1 
ATOM   3224 N N    . ASN   A 1 215 ? 1.575  28.419 43.833 1   23.83  ? 724  ASN   A N    1 
ATOM   3225 C CA   . ASN   A 1 215 ? 1.824  27.384 44.831 1   25.066 ? 724  ASN   A CA   1 
ATOM   3226 C C    . ASN   A 1 215 ? 2.613  26.209 44.247 1   24.49  ? 724  ASN   A C    1 
ATOM   3227 O O    . ASN   A 1 215 ? 2.471  25.089 44.739 1   25.505 ? 724  ASN   A O    1 
ATOM   3228 C CB   . ASN   A 1 215 ? 0.538  26.885 45.5   1   27.89  ? 724  ASN   A CB   1 
ATOM   3229 C CG   . ASN   A 1 215 ? -0.183 27.995 46.23  1   33.622 ? 724  ASN   A CG   1 
ATOM   3230 O OD1  . ASN   A 1 215 ? 0.442  28.806 46.923 1   37.653 ? 724  ASN   A OD1  1 
ATOM   3231 N ND2  . ASN   A 1 215 ? -1.491 28.083 46.046 1   37.741 ? 724  ASN   A ND2  1 
ATOM   3232 H H    . ASN   A 1 215 ? 1.939  29.245 43.974 1   23.667 ? 724  ASN   A H    1 
ATOM   3233 H HA   . ASN   A 1 215 ? 2.376  27.786 45.538 1   25.233 ? 724  ASN   A HA   1 
ATOM   3234 H HB2  . ASN   A 1 215 ? -0.056 26.505 44.823 1   28.462 ? 724  ASN   A HB2  1 
ATOM   3235 H HB3  . ASN   A 1 215 ? 0.76   26.178 46.138 1   28.396 ? 724  ASN   A HB3  1 
ATOM   3236 H HD21 . ASN   A 1 215 ? -1.881 28.88  46.021 1   36.389 ? 724  ASN   A HD21 1 
ATOM   3237 H HD22 . ASN   A 1 215 ? -1.975 27.346 45.95  1   36.283 ? 724  ASN   A HD22 1 
ATOM   3238 N N    . LYS   A 1 216 ? 3.492  26.46  43.261 1   22.247 ? 725  LYS   A N    1 
ATOM   3239 C CA   . LYS   A 1 216 ? 4.384  25.423 42.753 1   20.946 ? 725  LYS   A CA   1 
ATOM   3240 C C    . LYS   A 1 216 ? 5.784  25.595 43.341 1   22.036 ? 725  LYS   A C    1 
ATOM   3241 O O    . LYS   A 1 216 ? 6.596  24.675 43.296 1   23.659 ? 725  LYS   A O    1 
ATOM   3242 C CB   . LYS   A 1 216 ? 4.32   25.422 41.216 1   22.189 ? 725  LYS   A CB   1 
ATOM   3243 H H    . LYS   A 1 216 ? 3.533  27.296 42.896 1   22.447 ? 725  LYS   A H    1 
ATOM   3244 H HA   . LYS   A 1 216 ? 4.037  24.545 43.056 1   21.657 ? 725  LYS   A HA   1 
ATOM   3245 H HB2  . LYS   A 1 216 ? 5.26   25.449 40.874 0   30     ? 725  LYS   A HB2  1 
ATOM   3246 H HB3  . LYS   A 1 216 ? 3.402  25.448 40.926 0   30     ? 725  LYS   A HB3  1 
ATOM   3247 N N    . LEU   A 1 217 ? 6.079  26.792 43.878 1   18.191 ? 726  LEU   A N    1 
ATOM   3248 C CA   . LEU   A 1 217 ? 7.339  27.091 44.521 1   17.569 ? 726  LEU   A CA   1 
ATOM   3249 C C    . LEU   A 1 217 ? 7.006  27.708 45.87  1   18.104 ? 726  LEU   A C    1 
ATOM   3250 O O    . LEU   A 1 217 ? 6.21   28.641 45.914 1   18.249 ? 726  LEU   A O    1 
ATOM   3251 C CB   . LEU   A 1 217 ? 8.171  28.017 43.618 1   17.198 ? 726  LEU   A CB   1 
ATOM   3252 C CG   . LEU   A 1 217 ? 9.52   28.485 44.183 1   17.117 ? 726  LEU   A CG   1 
ATOM   3253 C CD1  . LEU   A 1 217 ? 10.468 27.314 44.387 1   16.376 ? 726  LEU   A CD1  1 
ATOM   3254 C CD2  . LEU   A 1 217 ? 10.204 29.545 43.327 1   16.578 ? 726  LEU   A CD2  1 
ATOM   3255 H H    . LEU   A 1 217 ? 5.457  27.459 43.828 1   18.953 ? 726  LEU   A H    1 
ATOM   3256 H HA   . LEU   A 1 217 ? 7.832  26.245 44.666 1   17.777 ? 726  LEU   A HA   1 
ATOM   3257 H HB2  . LEU   A 1 217 ? 8.338  27.547 42.768 1   17.263 ? 726  LEU   A HB2  1 
ATOM   3258 H HB3  . LEU   A 1 217 ? 7.628  28.813 43.413 1   17.263 ? 726  LEU   A HB3  1 
ATOM   3259 H HG   . LEU   A 1 217 ? 9.352  28.89  45.073 1   16.895 ? 726  LEU   A HG   1 
ATOM   3260 H HD11 . LEU   A 1 217 ? 10.101 26.712 45.055 1   16.717 ? 726  LEU   A HD11 1 
ATOM   3261 H HD12 . LEU   A 1 217 ? 11.331 27.644 44.69  1   16.61  ? 726  LEU   A HD12 1 
ATOM   3262 H HD13 . LEU   A 1 217 ? 10.58  26.837 43.548 1   16.619 ? 726  LEU   A HD13 1 
ATOM   3263 H HD21 . LEU   A 1 217 ? 9.638  30.333 43.272 1   16.736 ? 726  LEU   A HD21 1 
ATOM   3264 H HD22 . LEU   A 1 217 ? 10.354 29.194 42.434 1   16.738 ? 726  LEU   A HD22 1 
ATOM   3265 H HD23 . LEU   A 1 217 ? 11.056 29.786 43.727 1   16.735 ? 726  LEU   A HD23 1 
ATOM   3266 N N    . HIS   A 1 218 ? 7.59   27.196 46.961 1   19.27  ? 727  HIS   A N    1 
ATOM   3267 C CA   . HIS   A 1 218 ? 7.255  27.683 48.292 1   20.862 ? 727  HIS   A CA   1 
ATOM   3268 C C    . HIS   A 1 218 ? 7.98   28.982 48.657 1   17.681 ? 727  HIS   A C    1 
ATOM   3269 O O    . HIS   A 1 218 ? 7.439  29.81  49.38  1   15.339 ? 727  HIS   A O    1 
ATOM   3270 C CB   . HIS   A 1 218 ? 7.468  26.612 49.366 1   26.885 ? 727  HIS   A CB   1 
ATOM   3271 C CG   . HIS   A 1 218 ? 6.194  26.028 49.886 1   40.134 ? 727  HIS   A CG   1 
ATOM   3272 N ND1  . HIS   A 1 218 ? 5.492  26.545 50.963 1   47.734 ? 727  HIS   A ND1  1 
ATOM   3273 C CD2  . HIS   A 1 218 ? 5.517  24.939 49.473 1   49.287 ? 727  HIS   A CD2  1 
ATOM   3274 C CE1  . HIS   A 1 218 ? 4.414  25.801 51.174 1   56.713 ? 727  HIS   A CE1  1 
ATOM   3275 N NE2  . HIS   A 1 218 ? 4.417  24.812 50.286 1   57.702 ? 727  HIS   A NE2  1 
ATOM   3276 H H    . HIS   A 1 218 ? 8.214  26.534 46.874 1   19.363 ? 727  HIS   A H    1 
ATOM   3277 H HA   . HIS   A 1 218 ? 6.285  27.881 48.279 1   20.947 ? 727  HIS   A HA   1 
ATOM   3278 H HB2  . HIS   A 1 218 ? 8.017  25.891 48.992 1   27.764 ? 727  HIS   A HB2  1 
ATOM   3279 H HB3  . HIS   A 1 218 ? 7.964  27.009 50.113 1   27.964 ? 727  HIS   A HB3  1 
ATOM   3280 H HD1  . HIS   A 1 218 ? 5.709  27.23  51.427 0   30     ? 727  HIS   A HD1  1 
ATOM   3281 H HD2  . HIS   A 1 218 ? 5.746  24.37  48.765 1   48.6   ? 727  HIS   A HD2  1 
ATOM   3282 H HE1  . HIS   A 1 218 ? 3.769  25.939 51.847 1   54.495 ? 727  HIS   A HE1  1 
ATOM   3283 H HE2  . HIS   A 1 218 ? 3.842  24.133 50.208 0   30     ? 727  HIS   A HE2  1 
ATOM   3284 N N    . ALA   A 1 219 ? 9.207  29.152 48.178 1   16.228 ? 728  ALA   A N    1 
ATOM   3285 C CA   . ALA   A 1 219 ? 10.044 30.278 48.555 1   14.373 ? 728  ALA   A CA   1 
ATOM   3286 C C    . ALA   A 1 219 ? 11.005 30.582 47.413 1   14.543 ? 728  ALA   A C    1 
ATOM   3287 O O    . ALA   A 1 219 ? 11.562 29.672 46.807 1   14.315 ? 728  ALA   A O    1 
ATOM   3288 C CB   . ALA   A 1 219 ? 10.792 30.017 49.831 1   13.994 ? 728  ALA   A CB   1 
ATOM   3289 H H    . ALA   A 1 219 ? 9.545  28.536 47.594 1   16.151 ? 728  ALA   A H    1 
ATOM   3290 H HA   . ALA   A 1 219 ? 9.455  31.07  48.683 1   14.66  ? 728  ALA   A HA   1 
ATOM   3291 H HB1  . ALA   A 1 219 ? 10.161 29.855 50.552 1   14.122 ? 728  ALA   A HB1  1 
ATOM   3292 H HB2  . ALA   A 1 219 ? 11.362 29.239 49.722 1   14.172 ? 728  ALA   A HB2  1 
ATOM   3293 H HB3  . ALA   A 1 219 ? 11.34  30.789 50.051 1   14.122 ? 728  ALA   A HB3  1 
ATOM   3294 N N    . PHE   A 1 220 ? 11.158 31.874 47.121 1   13.169 ? 729  PHE   A N    1 
ATOM   3295 C CA   . PHE   A 1 220 ? 12.016 32.323 46.041 1   12.697 ? 729  PHE   A CA   1 
ATOM   3296 C C    . PHE   A 1 220 ? 13.047 33.293 46.595 1   11.544 ? 729  PHE   A C    1 
ATOM   3297 O O    . PHE   A 1 220 ? 12.683 34.32  47.166 1   12.187 ? 729  PHE   A O    1 
ATOM   3298 C CB   . PHE   A 1 220 ? 11.197 32.982 44.934 1   12.749 ? 729  PHE   A CB   1 
ATOM   3299 C CG   . PHE   A 1 220 ? 11.983 33.618 43.793 1   12.568 ? 729  PHE   A CG   1 
ATOM   3300 C CD1  . PHE   A 1 220 ? 13.093 32.991 43.244 1   12.132 ? 729  PHE   A CD1  1 
ATOM   3301 C CD2  . PHE   A 1 220 ? 11.56  34.815 43.237 1   12.72  ? 729  PHE   A CD2  1 
ATOM   3302 C CE1  . PHE   A 1 220 ? 13.775 33.562 42.194 1   11.843 ? 729  PHE   A CE1  1 
ATOM   3303 C CE2  . PHE   A 1 220 ? 12.256 35.391 42.191 1   11.715 ? 729  PHE   A CE2  1 
ATOM   3304 C CZ   . PHE   A 1 220 ? 13.352 34.767 41.669 1   12.526 ? 729  PHE   A CZ   1 
ATOM   3305 H H    . PHE   A 1 220 ? 10.712 32.501 47.614 1   13.391 ? 729  PHE   A H    1 
ATOM   3306 H HA   . PHE   A 1 220 ? 12.487 31.537 45.66  1   12.585 ? 729  PHE   A HA   1 
ATOM   3307 H HB2  . PHE   A 1 220 ? 10.595 32.304 44.556 1   12.695 ? 729  PHE   A HB2  1 
ATOM   3308 H HB3  . PHE   A 1 220 ? 10.631 33.672 45.344 1   12.692 ? 729  PHE   A HB3  1 
ATOM   3309 H HD1  . PHE   A 1 220 ? 13.384 32.167 43.596 1   12.183 ? 729  PHE   A HD1  1 
ATOM   3310 H HD2  . PHE   A 1 220 ? 10.804 35.253 43.594 1   12.44  ? 729  PHE   A HD2  1 
ATOM   3311 H HE1  . PHE   A 1 220 ? 14.537 33.133 41.837 1   12.08  ? 729  PHE   A HE1  1 
ATOM   3312 H HE2  . PHE   A 1 220 ? 11.966 36.214 41.83  1   12.134 ? 729  PHE   A HE2  1 
ATOM   3313 H HZ   . PHE   A 1 220 ? 13.823 35.162 40.953 1   12.174 ? 729  PHE   A HZ   1 
ATOM   3314 N N    . ILE   A 1 221 ? 14.324 32.937 46.429 1   11.704 ? 730  ILE   A N    1 
ATOM   3315 C CA   . ILE   A 1 221 ? 15.441 33.703 46.973 1   11.556 ? 730  ILE   A CA   1 
ATOM   3316 C C    . ILE   A 1 221 ? 15.984 34.607 45.868 1   10.827 ? 730  ILE   A C    1 
ATOM   3317 O O    . ILE   A 1 221 ? 16.424 34.115 44.814 1   10.437 ? 730  ILE   A O    1 
ATOM   3318 C CB   . ILE   A 1 221 ? 16.531 32.76  47.512 1   12.876 ? 730  ILE   A CB   1 
ATOM   3319 C CG1  . ILE   A 1 221 ? 15.988 31.887 48.661 1   15.031 ? 730  ILE   A CG1  1 
ATOM   3320 C CG2  . ILE   A 1 221 ? 17.778 33.557 47.904 1   13.775 ? 730  ILE   A CG2  1 
ATOM   3321 C CD1  . ILE   A 1 221 ? 16.837 30.66  48.955 1   17.826 ? 730  ILE   A CD1  1 
ATOM   3322 H H    . ILE   A 1 221 ? 14.512 32.18  45.953 1   11.648 ? 730  ILE   A H    1 
ATOM   3323 H HA   . ILE   A 1 221 ? 15.117 34.257 47.708 1   11.656 ? 730  ILE   A HA   1 
ATOM   3324 H HB   . ILE   A 1 221 ? 16.783 32.158 46.783 1   13.152 ? 730  ILE   A HB   1 
ATOM   3325 H HG12 . ILE   A 1 221 ? 15.934 32.433 49.472 1   15.099 ? 730  ILE   A HG12 1 
ATOM   3326 H HG13 . ILE   A 1 221 ? 15.082 31.594 48.436 1   15.055 ? 730  ILE   A HG13 1 
ATOM   3327 H HG21 . ILE   A 1 221 ? 18.305 33.047 48.542 1   13.545 ? 730  ILE   A HG21 1 
ATOM   3328 H HG22 . ILE   A 1 221 ? 17.513 34.4   48.308 1   13.487 ? 730  ILE   A HG22 1 
ATOM   3329 H HG23 . ILE   A 1 221 ? 18.316 33.733 47.113 1   13.495 ? 730  ILE   A HG23 1 
ATOM   3330 H HD11 . ILE   A 1 221 ? 16.865 30.088 48.166 1   17.027 ? 730  ILE   A HD11 1 
ATOM   3331 H HD12 . ILE   A 1 221 ? 16.446 30.165 49.7   1   16.964 ? 730  ILE   A HD12 1 
ATOM   3332 H HD13 . ILE   A 1 221 ? 17.744 30.933 49.189 1   16.944 ? 730  ILE   A HD13 1 
ATOM   3333 N N    . TRP   A 1 222 ? 15.91  35.931 46.084 1   9.874  ? 731  TRP   A N    1 
ATOM   3334 C CA   . TRP   A 1 222 ? 16.214 36.854 44.99  1   9.116  ? 731  TRP   A CA   1 
ATOM   3335 C C    . TRP   A 1 222 ? 16.439 38.278 45.494 1   8.294  ? 731  TRP   A C    1 
ATOM   3336 O O    . TRP   A 1 222 ? 16.389 38.531 46.694 1   8.831  ? 731  TRP   A O    1 
ATOM   3337 C CB   . TRP   A 1 222 ? 15.09  36.796 43.939 1   9.364  ? 731  TRP   A CB   1 
ATOM   3338 C CG   . TRP   A 1 222 ? 15.406 37.445 42.614 1   9.485  ? 731  TRP   A CG   1 
ATOM   3339 C CD1  . TRP   A 1 222 ? 14.745 38.465 41.996 1   9.358  ? 731  TRP   A CD1  1 
ATOM   3340 C CD2  . TRP   A 1 222 ? 16.456 37.061 41.704 1   9.745  ? 731  TRP   A CD2  1 
ATOM   3341 N NE1  . TRP   A 1 222 ? 15.318 38.755 40.785 1   9.604  ? 731  TRP   A NE1  1 
ATOM   3342 C CE2  . TRP   A 1 222 ? 16.368 37.905 40.58  1   9.704  ? 731  TRP   A CE2  1 
ATOM   3343 C CE3  . TRP   A 1 222 ? 17.466 36.099 41.763 1   9.961  ? 731  TRP   A CE3  1 
ATOM   3344 C CZ2  . TRP   A 1 222 ? 17.234 37.801 39.499 1   9.957  ? 731  TRP   A CZ2  1 
ATOM   3345 C CZ3  . TRP   A 1 222 ? 18.327 35.999 40.695 1   10.519 ? 731  TRP   A CZ3  1 
ATOM   3346 C CH2  . TRP   A 1 222 ? 18.208 36.836 39.58  1   10.497 ? 731  TRP   A CH2  1 
ATOM   3347 H H    . TRP   A 1 222 ? 15.675 36.26  46.903 1   9.929  ? 731  TRP   A H    1 
ATOM   3348 H HA   . TRP   A 1 222 ? 17.054 36.548 44.555 1   9.168  ? 731  TRP   A HA   1 
ATOM   3349 H HB2  . TRP   A 1 222 ? 14.86  35.856 43.779 1   9.361  ? 731  TRP   A HB2  1 
ATOM   3350 H HB3  . TRP   A 1 222 ? 14.293 37.227 44.315 1   9.339  ? 731  TRP   A HB3  1 
ATOM   3351 H HD1  . TRP   A 1 222 ? 13.997 38.919 42.351 1   9.448  ? 731  TRP   A HD1  1 
ATOM   3352 H HE1  . TRP   A 1 222 ? 15.047 39.372 40.231 1   9.571  ? 731  TRP   A HE1  1 
ATOM   3353 H HE3  . TRP   A 1 222 ? 17.544 35.525 42.506 1   10.047 ? 731  TRP   A HE3  1 
ATOM   3354 H HZ2  . TRP   A 1 222 ? 17.161 38.37  38.752 1   10.021 ? 731  TRP   A HZ2  1 
ATOM   3355 H HZ3  . TRP   A 1 222 ? 19.007 35.346 40.71  1   10.388 ? 731  TRP   A HZ3  1 
ATOM   3356 H HH2  . TRP   A 1 222 ? 18.817 36.743 38.869 1   10.359 ? 731  TRP   A HH2  1 
ATOM   3357 N N    . ASP   A 1 223 ? 16.791 39.186 44.564 1   8.303  ? 732  ASP   A N    1 
ATOM   3358 C CA   . ASP   A 1 223 ? 17.124 40.556 44.895 1   8.3    ? 732  ASP   A CA   1 
ATOM   3359 C C    . ASP   A 1 223 ? 15.976 41.248 45.629 1   8.088  ? 732  ASP   A C    1 
ATOM   3360 O O    . ASP   A 1 223 ? 14.855 41.234 45.133 1   8.626  ? 732  ASP   A O    1 
ATOM   3361 C CB   . ASP   A 1 223 ? 17.431 41.347 43.635 1   8.733  ? 732  ASP   A CB   1 
ATOM   3362 C CG   . ASP   A 1 223 ? 18.696 40.897 42.937 1   9.241  ? 732  ASP   A CG   1 
ATOM   3363 O OD1  . ASP   A 1 223 ? 19.657 40.595 43.664 1   9.538  ? 732  ASP   A OD1  1 
ATOM   3364 O OD2  . ASP   A 1 223 ? 18.713 40.904 41.695 1   9.47   ? 732  ASP   A OD2  1 
ATOM   3365 H H    . ASP   A 1 223 ? 16.854 38.925 43.691 1   8.34   ? 732  ASP   A H    1 
ATOM   3366 H HA   . ASP   A 1 223 ? 17.919 40.552 45.474 1   8.348  ? 732  ASP   A HA   1 
ATOM   3367 H HB2  . ASP   A 1 223 ? 16.683 41.242 43.01  1   8.752  ? 732  ASP   A HB2  1 
ATOM   3368 H HB3  . ASP   A 1 223 ? 17.512 42.298 43.848 1   8.757  ? 732  ASP   A HB3  1 
ATOM   3369 N N    . SER   A 1 224 ? 16.271 41.883 46.774 1   7.67   ? 733  SER   A N    1 
ATOM   3370 C CA   . SER   A 1 224 ? 15.268 42.633 47.528 1   7.89   ? 733  SER   A CA   1 
ATOM   3371 C C    . SER   A 1 224 ? 14.66  43.78  46.724 1   7.916  ? 733  SER   A C    1 
ATOM   3372 O O    . SER   A 1 224 ? 13.485 44.069 46.866 1   7.614  ? 733  SER   A O    1 
ATOM   3373 C CB   . SER   A 1 224 ? 15.825 43.176 48.813 1   7.9    ? 733  SER   A CB   1 
ATOM   3374 O OG   . SER   A 1 224 ? 16.933 44.037 48.596 1   8.1    ? 733  SER   A OG   1 
ATOM   3375 H H    . SER   A 1 224 ? 17.125 41.849 47.096 1   7.835  ? 733  SER   A H    1 
ATOM   3376 H HA   . SER   A 1 224 ? 14.536 42.006 47.755 1   7.887  ? 733  SER   A HA   1 
ATOM   3377 H HB2  . SER   A 1 224 ? 15.124 43.666 49.284 1   7.945  ? 733  SER   A HB2  1 
ATOM   3378 H HB3  . SER   A 1 224 ? 16.102 42.431 49.38  1   7.945  ? 733  SER   A HB3  1 
ATOM   3379 H HG   . SER   A 1 224 ? 17.214 44.311 49.338 0   30     ? 733  SER   A HG   1 
ATOM   3380 N N    . ALA   A 1 225 ? 15.481 44.446 45.903 1   8.436  ? 734  ALA   A N    1 
ATOM   3381 C CA   . ALA   A 1 225 ? 15.007 45.56  45.089 1   9.249  ? 734  ALA   A CA   1 
ATOM   3382 C C    . ALA   A 1 225 ? 13.918 45.106 44.117 1   9.35   ? 734  ALA   A C    1 
ATOM   3383 O O    . ALA   A 1 225 ? 12.983 45.862 43.874 1   10.701 ? 734  ALA   A O    1 
ATOM   3384 C CB   . ALA   A 1 225 ? 16.143 46.229 44.346 1   9.844  ? 734  ALA   A CB   1 
ATOM   3385 H H    . ALA   A 1 225 ? 16.361 44.205 45.85  1   8.481  ? 734  ALA   A H    1 
ATOM   3386 H HA   . ALA   A 1 225 ? 14.599 46.229 45.705 1   9.207  ? 734  ALA   A HA   1 
ATOM   3387 H HB1  . ALA   A 1 225 ? 16.868 46.424 44.963 1   9.673  ? 734  ALA   A HB1  1 
ATOM   3388 H HB2  . ALA   A 1 225 ? 16.467 45.639 43.645 1   9.67   ? 734  ALA   A HB2  1 
ATOM   3389 H HB3  . ALA   A 1 225 ? 15.829 47.058 43.948 1   9.704  ? 734  ALA   A HB3  1 
ATOM   3390 N N    . VAL   A 1 226 ? 13.994 43.867 43.614 1   8.83   ? 735  VAL   A N    1 
ATOM   3391 C CA   . VAL   A 1 226 ? 12.928 43.322 42.804 1   8.275  ? 735  VAL   A CA   1 
ATOM   3392 C C    . VAL   A 1 226 ? 11.803 42.736 43.664 1   8.586  ? 735  VAL   A C    1 
ATOM   3393 O O    . VAL   A 1 226 ? 10.631 43.002 43.404 1   8.07   ? 735  VAL   A O    1 
ATOM   3394 C CB   . VAL   A 1 226 ? 13.49  42.26  41.858 1   8.497  ? 735  VAL   A CB   1 
ATOM   3395 C CG1  . VAL   A 1 226 ? 12.369 41.477 41.165 1   8.504  ? 735  VAL   A CG1  1 
ATOM   3396 C CG2  . VAL   A 1 226 ? 14.468 42.865 40.852 1   8.673  ? 735  VAL   A CG2  1 
ATOM   3397 H H    . VAL   A 1 226 ? 14.732 43.355 43.778 1   8.816  ? 735  VAL   A H    1 
ATOM   3398 H HA   . VAL   A 1 226 ? 12.555 44.044 42.262 1   8.492  ? 735  VAL   A HA   1 
ATOM   3399 H HB   . VAL   A 1 226 ? 13.995 41.62  42.413 1   8.491  ? 735  VAL   A HB   1 
ATOM   3400 H HG11 . VAL   A 1 226 ? 11.643 42.081 40.935 1   8.501  ? 735  VAL   A HG11 1 
ATOM   3401 H HG12 . VAL   A 1 226 ? 12.038 40.784 41.76  1   8.502  ? 735  VAL   A HG12 1 
ATOM   3402 H HG13 . VAL   A 1 226 ? 12.714 41.066 40.354 1   8.503  ? 735  VAL   A HG13 1 
ATOM   3403 H HG21 . VAL   A 1 226 ? 14.787 42.171 40.251 1   8.632  ? 735  VAL   A HG21 1 
ATOM   3404 H HG22 . VAL   A 1 226 ? 15.222 43.254 41.324 1   8.624  ? 735  VAL   A HG22 1 
ATOM   3405 H HG23 . VAL   A 1 226 ? 14.018 43.555 40.337 1   8.624  ? 735  VAL   A HG23 1 
ATOM   3406 N N    . LEU   A 1 227 ? 12.126 41.875 44.636 1   7.98   ? 736  LEU   A N    1 
ATOM   3407 C CA   . LEU   A 1 227 ? 11.078 41.165 45.374 1   8.381  ? 736  LEU   A CA   1 
ATOM   3408 C C    . LEU   A 1 227 ? 10.189 42.097 46.203 1   8.819  ? 736  LEU   A C    1 
ATOM   3409 O O    . LEU   A 1 227 ? 8.972  41.849 46.308 1   9.244  ? 736  LEU   A O    1 
ATOM   3410 C CB   . LEU   A 1 227 ? 11.668 40.083 46.269 1   8.638  ? 736  LEU   A CB   1 
ATOM   3411 C CG   . LEU   A 1 227 ? 12.337 38.908 45.554 1   9.053  ? 736  LEU   A CG   1 
ATOM   3412 C CD1  . LEU   A 1 227 ? 12.736 37.881 46.577 1   9.43   ? 736  LEU   A CD1  1 
ATOM   3413 C CD2  . LEU   A 1 227 ? 11.49  38.276 44.409 1   9.138  ? 736  LEU   A CD2  1 
ATOM   3414 H H    . LEU   A 1 227 ? 13.003 41.724 44.844 1   8.217  ? 736  LEU   A H    1 
ATOM   3415 H HA   . LEU   A 1 227 ? 10.494 40.728 44.705 1   8.433  ? 736  LEU   A HA   1 
ATOM   3416 H HB2  . LEU   A 1 227 ? 12.332 40.504 46.862 1   8.672  ? 736  LEU   A HB2  1 
ATOM   3417 H HB3  . LEU   A 1 227 ? 10.945 39.729 46.838 1   8.679  ? 736  LEU   A HB3  1 
ATOM   3418 H HG   . LEU   A 1 227 ? 13.172 39.247 45.142 1   9.058  ? 736  LEU   A HG   1 
ATOM   3419 H HD11 . LEU   A 1 227 ? 13.554 38.165 47.019 1   9.318  ? 736  LEU   A HD11 1 
ATOM   3420 H HD12 . LEU   A 1 227 ? 12.887 37.026 46.14  1   9.316  ? 736  LEU   A HD12 1 
ATOM   3421 H HD13 . LEU   A 1 227 ? 12.03  37.785 47.237 1   9.326  ? 736  LEU   A HD13 1 
ATOM   3422 H HD21 . LEU   A 1 227 ? 11.452 38.889 43.655 1   9.111  ? 736  LEU   A HD21 1 
ATOM   3423 H HD22 . LEU   A 1 227 ? 10.589 38.1   44.728 1   9.118  ? 736  LEU   A HD22 1 
ATOM   3424 H HD23 . LEU   A 1 227 ? 11.9   37.442 44.124 1   9.139  ? 736  LEU   A HD23 1 
ATOM   3425 N N    . GLU   A 1 228 ? 10.776 43.142 46.807 1   8.644  ? 737  GLU   A N    1 
ATOM   3426 C CA   . GLU   A 1 228 ? 9.996  44.06  47.631 1   9.187  ? 737  GLU   A CA   1 
ATOM   3427 C C    . GLU   A 1 228 ? 9.008  44.838 46.76  1   8.979  ? 737  GLU   A C    1 
ATOM   3428 O O    . GLU   A 1 228 ? 7.855  45.061 47.169 1   9.167  ? 737  GLU   A O    1 
ATOM   3429 C CB   . GLU   A 1 228 ? 10.849 44.947 48.527 1   9.34   ? 737  GLU   A CB   1 
ATOM   3430 C CG   . GLU   A 1 228 ? 11.612 44.143 49.582 1   9.319  ? 737  GLU   A CG   1 
ATOM   3431 C CD   . GLU   A 1 228 ? 12.506 44.938 50.523 1   10.034 ? 737  GLU   A CD   1 
ATOM   3432 O OE1  . GLU   A 1 228 ? 12.724 46.128 50.259 1   10.706 ? 737  GLU   A OE1  1 
ATOM   3433 O OE2  . GLU   A 1 228 ? 12.971 44.353 51.521 1   9.715  ? 737  GLU   A OE2  1 
ATOM   3434 H H    . GLU   A 1 228 ? 11.674 43.284 46.709 1   8.799  ? 737  GLU   A H    1 
ATOM   3435 H HA   . GLU   A 1 228 ? 9.456  43.504 48.25  1   9.069  ? 737  GLU   A HA   1 
ATOM   3436 H HB2  . GLU   A 1 228 ? 11.485 45.442 47.97  1   9.297  ? 737  GLU   A HB2  1 
ATOM   3437 H HB3  . GLU   A 1 228 ? 10.27  45.599 48.973 1   9.3    ? 737  GLU   A HB3  1 
ATOM   3438 H HG2  . GLU   A 1 228 ? 10.963 43.648 50.126 1   9.481  ? 737  GLU   A HG2  1 
ATOM   3439 H HG3  . GLU   A 1 228 ? 12.168 43.476 49.125 1   9.469  ? 737  GLU   A HG3  1 
ATOM   3440 N N    . PHE   A 1 229 ? 9.43   45.197 45.547 1   8.358  ? 738  PHE   A N    1 
ATOM   3441 C CA   . PHE   A 1 229 ? 8.513  45.766 44.568 1   9.002  ? 738  PHE   A CA   1 
ATOM   3442 C C    . PHE   A 1 229 ? 7.391  44.77  44.215 1   9.473  ? 738  PHE   A C    1 
ATOM   3443 O O    . PHE   A 1 229 ? 6.201  45.121 44.269 1   9.341  ? 738  PHE   A O    1 
ATOM   3444 C CB   . PHE   A 1 229 ? 9.277  46.181 43.309 1   9.432  ? 738  PHE   A CB   1 
ATOM   3445 C CG   . PHE   A 1 229 ? 8.325  46.581 42.196 1   9.764  ? 738  PHE   A CG   1 
ATOM   3446 C CD1  . PHE   A 1 229 ? 7.663  47.801 42.257 1   10.771 ? 738  PHE   A CD1  1 
ATOM   3447 C CD2  . PHE   A 1 229 ? 7.997  45.678 41.173 1   10.863 ? 738  PHE   A CD2  1 
ATOM   3448 C CE1  . PHE   A 1 229 ? 6.726  48.119 41.3   1   10.476 ? 738  PHE   A CE1  1 
ATOM   3449 C CE2  . PHE   A 1 229 ? 7.085  46.028 40.18  1   10.733 ? 738  PHE   A CE2  1 
ATOM   3450 C CZ   . PHE   A 1 229 ? 6.466  47.243 40.246 1   10.213 ? 738  PHE   A CZ   1 
ATOM   3451 H H    . PHE   A 1 229 ? 10.31  45.095 45.323 1   8.659  ? 738  PHE   A H    1 
ATOM   3452 H HA   . PHE   A 1 229 ? 8.098  46.577 44.964 1   9.055  ? 738  PHE   A HA   1 
ATOM   3453 H HB2  . PHE   A 1 229 ? 9.862  46.941 43.526 1   9.404  ? 738  PHE   A HB2  1 
ATOM   3454 H HB3  . PHE   A 1 229 ? 9.832  45.428 43.009 1   9.394  ? 738  PHE   A HB3  1 
ATOM   3455 H HD1  . PHE   A 1 229 ? 7.837  48.397 42.967 1   10.458 ? 738  PHE   A HD1  1 
ATOM   3456 H HD2  . PHE   A 1 229 ? 8.438  44.844 41.129 1   10.562 ? 738  PHE   A HD2  1 
ATOM   3457 H HE1  . PHE   A 1 229 ? 6.307  48.965 41.32  1   10.48  ? 738  PHE   A HE1  1 
ATOM   3458 H HE2  . PHE   A 1 229 ? 6.893  45.43  39.475 1   10.628 ? 738  PHE   A HE2  1 
ATOM   3459 H HZ   . PHE   A 1 229 ? 5.84   47.484 39.582 1   10.397 ? 738  PHE   A HZ   1 
ATOM   3460 N N    . GLU   A 1 230 ? 7.774  43.554 43.787 1   9.06   ? 739  GLU   A N    1 
ATOM   3461 C CA   . GLU   A 1 230 ? 6.808  42.526 43.401 1   9.965  ? 739  GLU   A CA   1 
ATOM   3462 C C    . GLU   A 1 230 ? 5.771  42.276 44.511 1   9.668  ? 739  GLU   A C    1 
ATOM   3463 O O    . GLU   A 1 230 ? 4.558  42.297 44.276 1   8.743  ? 739  GLU   A O    1 
ATOM   3464 C CB   . GLU   A 1 230 ? 7.51   41.241 42.961 1   10.947 ? 739  GLU   A CB   1 
ATOM   3465 C CG   . GLU   A 1 230 ? 8.255  41.335 41.634 1   12.812 ? 739  GLU   A CG   1 
ATOM   3466 C CD   . GLU   A 1 230 ? 7.311  41.506 40.465 1   16.39  ? 739  GLU   A CD   1 
ATOM   3467 O OE1  . GLU   A 1 230 ? 6.145  41.113 40.642 1   19.603 ? 739  GLU   A OE1  1 
ATOM   3468 O OE2  . GLU   A 1 230 ? 7.671  42.133 39.452 1   20.58  ? 739  GLU   A OE2  1 
ATOM   3469 H H    . GLU   A 1 230 ? 8.666  43.362 43.733 1   9.356  ? 739  GLU   A H    1 
ATOM   3470 H HA   . GLU   A 1 230 ? 6.315  42.869 42.614 1   9.961  ? 739  GLU   A HA   1 
ATOM   3471 H HB2  . GLU   A 1 230 ? 8.157  40.989 43.653 1   11.116 ? 739  GLU   A HB2  1 
ATOM   3472 H HB3  . GLU   A 1 230 ? 6.846  40.523 42.904 1   11.14  ? 739  GLU   A HB3  1 
ATOM   3473 H HG2  . GLU   A 1 230 ? 8.87   42.099 41.659 1   13.053 ? 739  GLU   A HG2  1 
ATOM   3474 H HG3  . GLU   A 1 230 ? 8.784  40.521 41.5   1   13.083 ? 739  GLU   A HG3  1 
ATOM   3475 N N    . ALA   A 1 231 ? 6.247  42.056 45.733 1   9.685  ? 740  ALA   A N    1 
ATOM   3476 C CA   . ALA   A 1 231 ? 5.394  41.785 46.875 1   9.696  ? 740  ALA   A CA   1 
ATOM   3477 C C    . ALA   A 1 231 ? 4.498  42.983 47.189 1   9.795  ? 740  ALA   A C    1 
ATOM   3478 O O    . ALA   A 1 231 ? 3.4    42.792 47.674 1   9.33   ? 740  ALA   A O    1 
ATOM   3479 C CB   . ALA   A 1 231 ? 6.253  41.42  48.08  1   10.207 ? 740  ALA   A CB   1 
ATOM   3480 H H    . ALA   A 1 231 ? 7.152  42.073 45.861 1   9.687  ? 740  ALA   A H    1 
ATOM   3481 H HA   . ALA   A 1 231 ? 4.808  41.011 46.648 1   9.797  ? 740  ALA   A HA   1 
ATOM   3482 H HB1  . ALA   A 1 231 ? 6.703  40.574 47.917 1   10.056 ? 740  ALA   A HB1  1 
ATOM   3483 H HB2  . ALA   A 1 231 ? 6.918  42.113 48.231 1   10.054 ? 740  ALA   A HB2  1 
ATOM   3484 H HB3  . ALA   A 1 231 ? 5.692  41.338 48.869 1   10.063 ? 740  ALA   A HB3  1 
ATOM   3485 N N    . SER   A 1 232 ? 4.988  44.212 46.925 1   9.527  ? 741  SER   A N    1 
ATOM   3486 C CA   . SER   A 1 232 ? 4.241  45.444 47.185 1   9.897  ? 741  SER   A CA   1 
ATOM   3487 C C    . SER   A 1 232 ? 3.217  45.713 46.08  1   9.663  ? 741  SER   A C    1 
ATOM   3488 O O    . SER   A 1 232 ? 2.233  46.426 46.328 1   9.661  ? 741  SER   A O    1 
ATOM   3489 C CB   . SER   A 1 232 ? 5.167  46.62  47.416 1   9.808  ? 741  SER   A CB   1 
ATOM   3490 O OG   . SER   A 1 232 ? 5.985  46.386 48.568 1   10.245 ? 741  SER   A OG   1 
ATOM   3491 H H    . SER   A 1 232 ? 5.831  44.285 46.579 1   9.673  ? 741  SER   A H    1 
ATOM   3492 H HA   . SER   A 1 232 ? 3.734  45.305 48.023 1   9.763  ? 741  SER   A HA   1 
ATOM   3493 H HB2  . SER   A 1 232 ? 5.735  46.747 46.632 1   9.931  ? 741  SER   A HB2  1 
ATOM   3494 H HB3  . SER   A 1 232 ? 4.638  47.43  47.549 1   9.931  ? 741  SER   A HB3  1 
ATOM   3495 H HG   . SER   A 1 232 ? 6.485  47.051 48.677 0   30     ? 741  SER   A HG   1 
ATOM   3496 N N    . GLN   A 1 233 ? 3.382  45.04  44.935 1   10.765 ? 742  GLN   A N    1 
ATOM   3497 C CA   . GLN   A 1 233 ? 2.507  45.205 43.772 1   12.609 ? 742  GLN   A CA   1 
ATOM   3498 C C    . GLN   A 1 233 ? 1.408  44.147 43.782 1   12.423 ? 742  GLN   A C    1 
ATOM   3499 O O    . GLN   A 1 233 ? 0.328  44.351 43.218 1   12.219 ? 742  GLN   A O    1 
ATOM   3500 C CB   . GLN   A 1 233 ? 3.331  45.107 42.484 1   15.063 ? 742  GLN   A CB   1 
ATOM   3501 C CG   . GLN   A 1 233 ? 2.507  45.03  41.198 1   20.372 ? 742  GLN   A CG   1 
ATOM   3502 C CD   . GLN   A 1 233 ? 3.326  44.847 39.937 1   24.751 ? 742  GLN   A CD   1 
ATOM   3503 O OE1  . GLN   A 1 233 ? 3.178  45.583 38.952 1   33.432 ? 742  GLN   A OE1  1 
ATOM   3504 N NE2  . GLN   A 1 233 ? 4.187  43.846 39.935 1   30.787 ? 742  GLN   A NE2  1 
ATOM   3505 H H    . GLN   A 1 233 ? 4.089  44.467 44.861 1   10.906 ? 742  GLN   A H    1 
ATOM   3506 H HA   . GLN   A 1 233 ? 2.088  46.102 43.817 1   12.561 ? 742  GLN   A HA   1 
ATOM   3507 H HB2  . GLN   A 1 233 ? 3.921  45.888 42.433 1   15.518 ? 742  GLN   A HB2  1 
ATOM   3508 H HB3  . GLN   A 1 233 ? 3.9    44.311 42.542 1   15.589 ? 742  GLN   A HB3  1 
ATOM   3509 H HG2  . GLN   A 1 233 ? 1.881  44.278 41.261 1   19.791 ? 742  GLN   A HG2  1 
ATOM   3510 H HG3  . GLN   A 1 233 ? 1.976  45.85  41.109 1   19.874 ? 742  GLN   A HG3  1 
ATOM   3511 H HE21 . GLN   A 1 233 ? 4.842  43.829 39.337 1   28.712 ? 742  GLN   A HE21 1 
ATOM   3512 H HE22 . GLN   A 1 233 ? 4.113  43.192 40.529 1   28.348 ? 742  GLN   A HE22 1 
ATOM   3513 N N    . LYS   A 1 234 ? 1.713  43.022 44.416 1   11.863 ? 743  LYS   A N    1 
ATOM   3514 C CA   . LYS   A 1 234 ? 0.867  41.836 44.425 1   13.137 ? 743  LYS   A CA   1 
ATOM   3515 C C    . LYS   A 1 234 ? 0.456  41.477 45.854 1   12.732 ? 743  LYS   A C    1 
ATOM   3516 O O    . LYS   A 1 234 ? 1.255  40.968 46.637 1   10.68  ? 743  LYS   A O    1 
ATOM   3517 C CB   . LYS   A 1 234 ? 1.643  40.704 43.729 1   13.217 ? 743  LYS   A CB   1 
ATOM   3518 C CG   . LYS   A 1 234 ? 1.949  40.997 42.254 1   14.702 ? 743  LYS   A CG   1 
ATOM   3519 C CD   . LYS   A 1 234 ? 3.062  40.185 41.603 1   16.71  ? 743  LYS   A CD   1 
ATOM   3520 C CE   . LYS   A 1 234 ? 2.968  40.429 40.114 1   18.487 ? 743  LYS   A CE   1 
ATOM   3521 N NZ   . LYS   A 1 234 ? 4.118  39.953 39.363 1   19.789 ? 743  LYS   A NZ   1 
ATOM   3522 H H    . LYS   A 1 234 ? 2.502  42.982 44.874 1   12.251 ? 743  LYS   A H    1 
ATOM   3523 H HA   . LYS   A 1 234 ? 0.051  42.026 43.897 1   12.826 ? 743  LYS   A HA   1 
ATOM   3524 H HB2  . LYS   A 1 234 ? 2.49   40.559 44.202 1   13.511 ? 743  LYS   A HB2  1 
ATOM   3525 H HB3  . LYS   A 1 234 ? 1.121  39.876 43.785 1   13.617 ? 743  LYS   A HB3  1 
ATOM   3526 H HG2  . LYS   A 1 234 ? 1.127  40.864 41.74  1   15.016 ? 743  LYS   A HG2  1 
ATOM   3527 H HG3  . LYS   A 1 234 ? 2.18   41.947 42.176 1   14.814 ? 743  LYS   A HG3  1 
ATOM   3528 H HD2  . LYS   A 1 234 ? 3.937  40.481 41.935 1   16.627 ? 743  LYS   A HD2  1 
ATOM   3529 H HD3  . LYS   A 1 234 ? 2.941  39.229 41.792 1   16.608 ? 743  LYS   A HD3  1 
ATOM   3530 H HE2  . LYS   A 1 234 ? 2.172  39.987 39.771 1   18.357 ? 743  LYS   A HE2  1 
ATOM   3531 H HE3  . LYS   A 1 234 ? 2.866  41.383 39.951 1   18.371 ? 743  LYS   A HE3  1 
ATOM   3532 H HZ1  . LYS   A 1 234 ? 4.258  39.075 39.541 1   19.375 ? 743  LYS   A HZ1  1 
ATOM   3533 H HZ2  . LYS   A 1 234 ? 4.853  40.425 39.597 1   19.363 ? 743  LYS   A HZ2  1 
ATOM   3534 H HZ3  . LYS   A 1 234 ? 3.968  40.056 38.475 1   19.375 ? 743  LYS   A HZ3  1 
ATOM   3535 N N    . CYS   A 1 235 ? -0.837 41.654 46.151 1   13.711 ? 744  CYS   A N    1 
ATOM   3536 C CA   . CYS   A 1 235 ? -1.364 41.551 47.503 1   15.644 ? 744  CYS   A CA   1 
ATOM   3537 C C    . CYS   A 1 235 ? -1.268 40.119 48.065 1   16.305 ? 744  CYS   A C    1 
ATOM   3538 O O    . CYS   A 1 235 ? -1.33  39.923 49.274 1   14.753 ? 744  CYS   A O    1 
ATOM   3539 C CB   . CYS   A 1 235 ? -2.828 42.021 47.546 1   17.782 ? 744  CYS   A CB   1 
ATOM   3540 S SG   . CYS   A 1 235 ? -3.23  43.584 46.694 1   22.738 ? 744  CYS   A SG   1 
ATOM   3541 H H    . CYS   A 1 235 ? -1.421 41.846 45.474 1   13.888 ? 744  CYS   A H    1 
ATOM   3542 H HA   . CYS   A 1 235 ? -0.828 42.149 48.083 1   15.736 ? 744  CYS   A HA   1 
ATOM   3543 H HB2  . CYS   A 1 235 ? -3.391 41.315 47.156 1   18.064 ? 744  CYS   A HB2  1 
ATOM   3544 H HB3  . CYS   A 1 235 ? -3.093 42.117 48.487 1   18.073 ? 744  CYS   A HB3  1 
ATOM   3545 N N    . ASP   A 1 236 ? -1.101 39.114 47.198 1   16.437 ? 745  ASP   A N    1 
ATOM   3546 C CA   . ASP   A 1 236 ? -1.004 37.718 47.613 1   16.88  ? 745  ASP   A CA   1 
ATOM   3547 C C    . ASP   A 1 236 ? 0.434  37.294 47.961 1   16.769 ? 745  ASP   A C    1 
ATOM   3548 O O    . ASP   A 1 236 ? 0.632  36.184 48.461 1   17.423 ? 745  ASP   A O    1 
ATOM   3549 C CB   . ASP   A 1 236 ? -1.573 36.804 46.535 1   16.768 ? 745  ASP   A CB   1 
ATOM   3550 C CG   . ASP   A 1 236 ? -0.859 36.922 45.191 1   18.316 ? 745  ASP   A CG   1 
ATOM   3551 O OD1  . ASP   A 1 236 ? -0.631 38.061 44.733 1   19.982 ? 745  ASP   A OD1  1 
ATOM   3552 O OD2  . ASP   A 1 236 ? -0.546 35.887 44.573 1   18.554 ? 745  ASP   A OD2  1 
ATOM   3553 H H    . ASP   A 1 236 ? -1.061 39.304 46.305 1   16.462 ? 745  ASP   A H    1 
ATOM   3554 H HA   . ASP   A 1 236 ? -1.562 37.596 48.413 1   16.817 ? 745  ASP   A HA   1 
ATOM   3555 H HB2  . ASP   A 1 236 ? -1.512 35.875 46.84  1   17.219 ? 745  ASP   A HB2  1 
ATOM   3556 H HB3  . ASP   A 1 236 ? -2.52  37.019 46.402 1   17.152 ? 745  ASP   A HB3  1 
ATOM   3557 N N    . LEU   A 1 237 ? 1.434  38.16  47.71  1   14.119 ? 746  LEU   A N    1 
ATOM   3558 C CA   . LEU   A 1 237 ? 2.84   37.822 47.861 1   14.06  ? 746  LEU   A CA   1 
ATOM   3559 C C    . LEU   A 1 237 ? 3.485  38.754 48.888 1   11.68  ? 746  LEU   A C    1 
ATOM   3560 O O    . LEU   A 1 237 ? 3.184  39.942 48.909 1   11.789 ? 746  LEU   A O    1 
ATOM   3561 C CB   . LEU   A 1 237 ? 3.554  37.951 46.511 1   14.362 ? 746  LEU   A CB   1 
ATOM   3562 C CG   . LEU   A 1 237 ? 3.116  37.029 45.375 1   14.694 ? 746  LEU   A CG   1 
ATOM   3563 C CD1  . LEU   A 1 237 ? 3.899  37.365 44.088 1   15.487 ? 746  LEU   A CD1  1 
ATOM   3564 C CD2  . LEU   A 1 237 ? 3.285  35.582 45.754 1   16.038 ? 746  LEU   A CD2  1 
ATOM   3565 H H    . LEU   A 1 237 ? 1.224  39.004 47.428 1   14.73  ? 746  LEU   A H    1 
ATOM   3566 H HA   . LEU   A 1 237 ? 2.912  36.888 48.183 1   13.681 ? 746  LEU   A HA   1 
ATOM   3567 H HB2  . LEU   A 1 237 ? 3.454  38.882 46.204 1   14.363 ? 746  LEU   A HB2  1 
ATOM   3568 H HB3  . LEU   A 1 237 ? 4.516  37.808 46.664 1   14.346 ? 746  LEU   A HB3  1 
ATOM   3569 H HG   . LEU   A 1 237 ? 2.153  37.191 45.2   1   15.019 ? 746  LEU   A HG   1 
ATOM   3570 H HD11 . LEU   A 1 237 ? 3.746  38.294 43.847 1   15.258 ? 746  LEU   A HD11 1 
ATOM   3571 H HD12 . LEU   A 1 237 ? 3.597  36.79  43.365 1   15.252 ? 746  LEU   A HD12 1 
ATOM   3572 H HD13 . LEU   A 1 237 ? 4.848  37.223 44.239 1   15.245 ? 746  LEU   A HD13 1 
ATOM   3573 H HD21 . LEU   A 1 237 ? 2.607  35.334 46.405 1   15.604 ? 746  LEU   A HD21 1 
ATOM   3574 H HD22 . LEU   A 1 237 ? 4.167  35.448 46.14  1   15.62  ? 746  LEU   A HD22 1 
ATOM   3575 H HD23 . LEU   A 1 237 ? 3.192  35.025 44.963 1   15.62  ? 746  LEU   A HD23 1 
ATOM   3576 N N    . VAL   A 1 238 ? 4.407  38.211 49.677 1   11.309 ? 747  VAL   A N    1 
ATOM   3577 C CA   . VAL   A 1 238 ? 5.102  38.948 50.731 1   11.935 ? 747  VAL   A CA   1 
ATOM   3578 C C    . VAL   A 1 238 ? 6.573  38.584 50.661 1   11.002 ? 747  VAL   A C    1 
ATOM   3579 O O    . VAL   A 1 238 ? 6.911  37.592 50.017 1   11.337 ? 747  VAL   A O    1 
ATOM   3580 C CB   . VAL   A 1 238 ? 4.537  38.737 52.151 1   12.34  ? 747  VAL   A CB   1 
ATOM   3581 C CG1  . VAL   A 1 238 ? 3.064  39.142 52.232 1   13.399 ? 747  VAL   A CG1  1 
ATOM   3582 C CG2  . VAL   A 1 238 ? 4.703  37.315 52.667 1   14.016 ? 747  VAL   A CG2  1 
ATOM   3583 H H    . VAL   A 1 238 ? 4.62   37.33  49.557 1   11.565 ? 747  VAL   A H    1 
ATOM   3584 H HA   . VAL   A 1 238 ? 5.025  39.899 50.525 1   11.687 ? 747  VAL   A HA   1 
ATOM   3585 H HB   . VAL   A 1 238 ? 5.043  39.332 52.753 1   12.754 ? 747  VAL   A HB   1 
ATOM   3586 H HG11 . VAL   A 1 238 ? 2.531  38.544 51.681 1   13.08  ? 747  VAL   A HG11 1 
ATOM   3587 H HG12 . VAL   A 1 238 ? 2.96   40.054 51.913 1   13.08  ? 747  VAL   A HG12 1 
ATOM   3588 H HG13 . VAL   A 1 238 ? 2.762  39.086 53.155 1   13.082 ? 747  VAL   A HG13 1 
ATOM   3589 H HG21 . VAL   A 1 238 ? 4.13   37.18  53.44  1   13.492 ? 747  VAL   A HG21 1 
ATOM   3590 H HG22 . VAL   A 1 238 ? 5.629  37.167 52.923 1   13.485 ? 747  VAL   A HG22 1 
ATOM   3591 H HG23 . VAL   A 1 238 ? 4.456  36.685 51.969 1   13.495 ? 747  VAL   A HG23 1 
ATOM   3592 N N    . THR   A 1 239 ? 7.412  39.403 51.306 1   10.53  ? 748  THR   A N    1 
ATOM   3593 C CA   . THR   A 1 239 ? 8.792  39.046 51.561 1   11.637 ? 748  THR   A CA   1 
ATOM   3594 C C    . THR   A 1 239 ? 8.941  38.796 53.051 1   14.5   ? 748  THR   A C    1 
ATOM   3595 O O    . THR   A 1 239 ? 8.099  39.19  53.874 1   12.521 ? 748  THR   A O    1 
ATOM   3596 C CB   . THR   A 1 239 ? 9.813  40.087 51.064 1   11.321 ? 748  THR   A CB   1 
ATOM   3597 O OG1  . THR   A 1 239 ? 9.502  41.338 51.679 1   11.057 ? 748  THR   A OG1  1 
ATOM   3598 C CG2  . THR   A 1 239 ? 9.792  40.218 49.547 1   11.579 ? 748  THR   A CG2  1 
ATOM   3599 H H    . THR   A 1 239 ? 7.105  40.21  51.605 1   10.897 ? 748  THR   A H    1 
ATOM   3600 H HA   . THR   A 1 239 ? 8.973  38.206 51.094 1   11.856 ? 748  THR   A HA   1 
ATOM   3601 H HB   . THR   A 1 239 ? 10.718 39.808 51.341 1   11.455 ? 748  THR   A HB   1 
ATOM   3602 H HG1  . THR   A 1 239 ? 8.706  41.587 51.453 0   30     ? 748  THR   A HG1  1 
ATOM   3603 H HG21 . THR   A 1 239 ? 10.445 40.883 49.27  1   11.502 ? 748  THR   A HG21 1 
ATOM   3604 H HG22 . THR   A 1 239 ? 8.907  40.495 49.257 1   11.502 ? 748  THR   A HG22 1 
ATOM   3605 H HG23 . THR   A 1 239 ? 10.011 39.362 49.144 1   11.502 ? 748  THR   A HG23 1 
ATOM   3606 N N    . THR   A 1 240 ? 10.026 38.116 53.39  1   16.936 ? 749  THR   A N    1 
ATOM   3607 C CA   . THR   A 1 240 ? 10.213 37.672 54.765 1   22.145 ? 749  THR   A CA   1 
ATOM   3608 C C    . THR   A 1 240 ? 11.701 37.573 55.068 1   23.393 ? 749  THR   A C    1 
ATOM   3609 O O    . THR   A 1 240 ? 12.526 37.261 54.21  1   19.636 ? 749  THR   A O    1 
ATOM   3610 C CB   . THR   A 1 240 ? 9.504  36.326 54.969 1   25.972 ? 749  THR   A CB   1 
ATOM   3611 O OG1  . THR   A 1 240 ? 9.514  35.991 56.356 1   30.441 ? 749  THR   A OG1  1 
ATOM   3612 C CG2  . THR   A 1 240 ? 10.159 35.197 54.192 1   26.837 ? 749  THR   A CG2  1 
ATOM   3613 H H    . THR   A 1 240 ? 10.662 37.919 52.763 1   17.179 ? 749  THR   A H    1 
ATOM   3614 H HA   . THR   A 1 240 ? 9.81   38.335 55.367 1   21.808 ? 749  THR   A HA   1 
ATOM   3615 H HB   . THR   A 1 240 ? 8.568  36.408 54.667 1   26.116 ? 749  THR   A HB   1 
ATOM   3616 H HG1  . THR   A 1 240 ? 10.34  35.932 56.638 0   30     ? 749  THR   A HG1  1 
ATOM   3617 H HG21 . THR   A 1 240 ? 9.524  34.468 54.083 1   26.558 ? 749  THR   A HG21 1 
ATOM   3618 H HG22 . THR   A 1 240 ? 10.938 34.876 54.677 1   26.546 ? 749  THR   A HG22 1 
ATOM   3619 H HG23 . THR   A 1 240 ? 10.432 35.519 53.317 1   26.505 ? 749  THR   A HG23 1 
ATOM   3620 N N    . GLY   A 1 241 ? 12.023 37.838 56.328 1   30.333 ? 750  GLY   A N    1 
ATOM   3621 C CA   . GLY   A 1 241 ? 13.388 37.739 56.796 1   33.549 ? 750  GLY   A CA   1 
ATOM   3622 C C    . GLY   A 1 241 ? 14.159 39.034 56.577 1   33.128 ? 750  GLY   A C    1 
ATOM   3623 O O    . GLY   A 1 241 ? 13.77  39.903 55.798 1   34.649 ? 750  GLY   A O    1 
ATOM   3624 H H    . GLY   A 1 241 ? 11.371 38.086 56.919 1   29.033 ? 750  GLY   A H    1 
ATOM   3625 H HA2  . GLY   A 1 241 ? 13.381 37.527 57.756 1   32.599 ? 750  GLY   A HA2  1 
ATOM   3626 H HA3  . GLY   A 1 241 ? 13.842 37.002 56.326 1   32.457 ? 750  GLY   A HA3  1 
ATOM   3627 N N    . GLU   A 1 242 ? 15.267 39.137 57.312 1   32.316 ? 751  GLU   A N    1 
ATOM   3628 C CA   . GLU   A 1 242 ? 16.225 40.206 57.119 1   31.586 ? 751  GLU   A CA   1 
ATOM   3629 C C    . GLU   A 1 242 ? 16.834 40.034 55.73  1   30.838 ? 751  GLU   A C    1 
ATOM   3630 O O    . GLU   A 1 242 ? 17.014 38.887 55.296 1   37.207 ? 751  GLU   A O    1 
ATOM   3631 C CB   . GLU   A 1 242 ? 17.286 40.105 58.221 1   33.237 ? 751  GLU   A CB   1 
ATOM   3632 H H    . GLU   A 1 242 ? 15.43  38.512 57.959 1   32.356 ? 751  GLU   A H    1 
ATOM   3633 H HA   . GLU   A 1 242 ? 15.753 41.076 57.172 1   31.833 ? 751  GLU   A HA   1 
ATOM   3634 H HB2  . GLU   A 1 242 ? 18.137 40.185 57.823 0   30     ? 751  GLU   A HB2  1 
ATOM   3635 H HB3  . GLU   A 1 242 ? 16.786 40.103 59.093 0   30     ? 751  GLU   A HB3  1 
ATOM   3636 N N    . LEU   A 1 243 ? 17.126 41.157 55.042 1   22.529 ? 752  LEU   A N    1 
ATOM   3637 C CA   . LEU   A 1 243 ? 18.036 41.134 53.907 1   21.752 ? 752  LEU   A CA   1 
ATOM   3638 C C    . LEU   A 1 243 ? 19.314 40.418 54.327 1   20.623 ? 752  LEU   A C    1 
ATOM   3639 O O    . LEU   A 1 243 ? 19.755 40.614 55.45  1   18.489 ? 752  LEU   A O    1 
ATOM   3640 C CB   . LEU   A 1 243 ? 18.373 42.531 53.391 1   21.279 ? 752  LEU   A CB   1 
ATOM   3641 C CG   . LEU   A 1 243 ? 17.466 43.118 52.306 1   22.308 ? 752  LEU   A CG   1 
ATOM   3642 C CD1  . LEU   A 1 243 ? 16.048 43.316 52.774 1   24.918 ? 752  LEU   A CD1  1 
ATOM   3643 C CD2  . LEU   A 1 243 ? 18.009 44.42  51.817 1   22.252 ? 752  LEU   A CD2  1 
ATOM   3644 H H    . LEU   A 1 243 ? 16.744 41.95  55.288 1   24.159 ? 752  LEU   A H    1 
ATOM   3645 H HA   . LEU   A 1 243 ? 17.606 40.618 53.183 1   21.48  ? 752  LEU   A HA   1 
ATOM   3646 H HB2  . LEU   A 1 243 ? 18.373 43.148 54.159 1   21.633 ? 752  LEU   A HB2  1 
ATOM   3647 H HB3  . LEU   A 1 243 ? 19.294 42.513 53.042 1   21.614 ? 752  LEU   A HB3  1 
ATOM   3648 H HG   . LEU   A 1 243 ? 17.451 42.486 51.542 1   22.569 ? 752  LEU   A HG   1 
ATOM   3649 H HD11 . LEU   A 1 243 ? 15.663 42.457 53.017 1   24.061 ? 752  LEU   A HD11 1 
ATOM   3650 H HD12 . LEU   A 1 243 ? 15.523 43.714 52.059 1   23.951 ? 752  LEU   A HD12 1 
ATOM   3651 H HD13 . LEU   A 1 243 ? 16.04  43.904 53.547 1   24.07  ? 752  LEU   A HD13 1 
ATOM   3652 H HD21 . LEU   A 1 243 ? 18.895 44.282 51.441 1   22.242 ? 752  LEU   A HD21 1 
ATOM   3653 H HD22 . LEU   A 1 243 ? 18.067 45.047 52.558 1   22.242 ? 752  LEU   A HD22 1 
ATOM   3654 H HD23 . LEU   A 1 243 ? 17.421 44.782 51.133 1   22.155 ? 752  LEU   A HD23 1 
ATOM   3655 N N    . PHE   A 1 244 ? 19.92  39.635 53.413 1   18.748 ? 753  PHE   A N    1 
ATOM   3656 C CA   . PHE   A 1 244 ? 21.26  39.087 53.591 1   16.6   ? 753  PHE   A CA   1 
ATOM   3657 C C    . PHE   A 1 244 ? 22.058 39.238 52.299 1   17.276 ? 753  PHE   A C    1 
ATOM   3658 O O    . PHE   A 1 244 ? 21.496 39.573 51.251 1   17.891 ? 753  PHE   A O    1 
ATOM   3659 C CB   . PHE   A 1 244 ? 21.158 37.628 54.035 1   18.669 ? 753  PHE   A CB   1 
ATOM   3660 C CG   . PHE   A 1 244 ? 20.37  36.729 53.094 1   16.247 ? 753  PHE   A CG   1 
ATOM   3661 C CD1  . PHE   A 1 244 ? 18.985 36.727 53.111 1   15.835 ? 753  PHE   A CD1  1 
ATOM   3662 C CD2  . PHE   A 1 244 ? 21.016 35.878 52.216 1   16.615 ? 753  PHE   A CD2  1 
ATOM   3663 C CE1  . PHE   A 1 244 ? 18.264 35.934 52.228 1   16.232 ? 753  PHE   A CE1  1 
ATOM   3664 C CE2  . PHE   A 1 244 ? 20.288 35.061 51.364 1   15.614 ? 753  PHE   A CE2  1 
ATOM   3665 C CZ   . PHE   A 1 244 ? 18.923 35.099 51.372 1   15.393 ? 753  PHE   A CZ   1 
ATOM   3666 H H    . PHE   A 1 244 ? 19.474 39.443 52.639 1   18.66  ? 753  PHE   A H    1 
ATOM   3667 H HA   . PHE   A 1 244 ? 21.72  39.602 54.306 1   17.514 ? 753  PHE   A HA   1 
ATOM   3668 H HB2  . PHE   A 1 244 ? 22.068 37.267 54.127 1   17.589 ? 753  PHE   A HB2  1 
ATOM   3669 H HB3  . PHE   A 1 244 ? 20.737 37.602 54.922 1   17.605 ? 753  PHE   A HB3  1 
ATOM   3670 H HD1  . PHE   A 1 244 ? 18.527 37.314 53.691 1   16.134 ? 753  PHE   A HD1  1 
ATOM   3671 H HD2  . PHE   A 1 244 ? 21.96  35.853 52.199 1   16.346 ? 753  PHE   A HD2  1 
ATOM   3672 H HE1  . PHE   A 1 244 ? 17.32  35.944 52.247 1   15.947 ? 753  PHE   A HE1  1 
ATOM   3673 H HE2  . PHE   A 1 244 ? 20.739 34.491 50.762 1   15.8   ? 753  PHE   A HE2  1 
ATOM   3674 H HZ   . PHE   A 1 244 ? 18.433 34.54  50.79  1   15.655 ? 753  PHE   A HZ   1 
ATOM   3675 N N    . PHE   A 1 245 ? 23.37  38.99  52.376 1   16.103 ? 754  PHE   A N    1 
ATOM   3676 C CA   . PHE   A 1 245 ? 24.298 39.273 51.287 1   17.194 ? 754  PHE   A CA   1 
ATOM   3677 C C    . PHE   A 1 245 ? 23.976 40.644 50.692 1   16.021 ? 754  PHE   A C    1 
ATOM   3678 O O    . PHE   A 1 245 ? 23.749 40.768 49.491 1   14.58  ? 754  PHE   A O    1 
ATOM   3679 C CB   . PHE   A 1 245 ? 24.311 38.17  50.222 1   20.496 ? 754  PHE   A CB   1 
ATOM   3680 C CG   . PHE   A 1 245 ? 24.724 36.777 50.702 1   24.193 ? 754  PHE   A CG   1 
ATOM   3681 C CD1  . PHE   A 1 245 ? 25.771 36.593 51.6   1   26.549 ? 754  PHE   A CD1  1 
ATOM   3682 C CD2  . PHE   A 1 245 ? 24.049 35.643 50.257 1   26.775 ? 754  PHE   A CD2  1 
ATOM   3683 C CE1  . PHE   A 1 245 ? 26.109 35.316 52.038 1   28.53  ? 754  PHE   A CE1  1 
ATOM   3684 C CE2  . PHE   A 1 245 ? 24.396 34.373 50.692 1   25.841 ? 754  PHE   A CE2  1 
ATOM   3685 C CZ   . PHE   A 1 245 ? 25.421 34.213 51.584 1   27.168 ? 754  PHE   A CZ   1 
ATOM   3686 H H    . PHE   A 1 245 ? 23.704 38.627 53.146 1   16.636 ? 754  PHE   A H    1 
ATOM   3687 H HA   . PHE   A 1 245 ? 25.21  39.325 51.678 1   17.392 ? 754  PHE   A HA   1 
ATOM   3688 H HB2  . PHE   A 1 245 ? 23.411 38.112 49.831 1   20.466 ? 754  PHE   A HB2  1 
ATOM   3689 H HB3  . PHE   A 1 245 ? 24.923 38.445 49.503 1   20.416 ? 754  PHE   A HB3  1 
ATOM   3690 H HD1  . PHE   A 1 245 ? 26.244 37.341 51.928 1   26.24  ? 754  PHE   A HD1  1 
ATOM   3691 H HD2  . PHE   A 1 245 ? 23.335 35.742 49.65  1   25.532 ? 754  PHE   A HD2  1 
ATOM   3692 H HE1  . PHE   A 1 245 ? 26.822 35.205 52.647 1   27.676 ? 754  PHE   A HE1  1 
ATOM   3693 H HE2  . PHE   A 1 245 ? 23.922 33.62  50.376 1   26.353 ? 754  PHE   A HE2  1 
ATOM   3694 H HZ   . PHE   A 1 245 ? 25.666 33.349 51.875 1   27.513 ? 754  PHE   A HZ   1 
ATOM   3695 N N    . ARG   A 1 246 ? 23.964 41.67  51.561 1   15.842 ? 755  ARG   A N    1 
ATOM   3696 C CA   . ARG   A 1 246 ? 23.811 43.041 51.125 1   15.189 ? 755  ARG   A CA   1 
ATOM   3697 C C    . ARG   A 1 246 ? 24.897 43.352 50.105 1   13.984 ? 755  ARG   A C    1 
ATOM   3698 O O    . ARG   A 1 246 ? 26.048 42.947 50.263 1   12.39  ? 755  ARG   A O    1 
ATOM   3699 C CB   . ARG   A 1 246 ? 23.907 44.007 52.304 1   18.022 ? 755  ARG   A CB   1 
ATOM   3700 C CG   . ARG   A 1 246 ? 22.596 44.094 53.055 1   20.156 ? 755  ARG   A CG   1 
ATOM   3701 C CD   . ARG   A 1 246 ? 22.679 45.181 54.117 1   22.7   ? 755  ARG   A CD   1 
ATOM   3702 N NE   . ARG   A 1 246 ? 21.428 45.058 54.877 1   27.228 ? 755  ARG   A NE   1 
ATOM   3703 C CZ   . ARG   A 1 246 ? 20.366 45.845 54.707 1   27.562 ? 755  ARG   A CZ   1 
ATOM   3704 N NH1  . ARG   A 1 246 ? 19.256 45.566 55.372 1   30.443 ? 755  ARG   A NH1  1 
ATOM   3705 N NH2  . ARG   A 1 246 ? 20.416 46.864 53.857 1   28.3   ? 755  ARG   A NH2  1 
ATOM   3706 H H    . ARG   A 1 246 ? 24.055 41.5   52.454 1   15.775 ? 755  ARG   A H    1 
ATOM   3707 H HA   . ARG   A 1 246 ? 22.925 43.133 50.695 1   15.519 ? 755  ARG   A HA   1 
ATOM   3708 H HB2  . ARG   A 1 246 ? 24.611 43.705 52.917 1   17.769 ? 755  ARG   A HB2  1 
ATOM   3709 H HB3  . ARG   A 1 246 ? 24.15  44.899 51.976 1   17.761 ? 755  ARG   A HB3  1 
ATOM   3710 H HG2  . ARG   A 1 246 ? 21.869 44.305 52.429 1   20.157 ? 755  ARG   A HG2  1 
ATOM   3711 H HG3  . ARG   A 1 246 ? 22.403 43.232 53.485 1   20.215 ? 755  ARG   A HG3  1 
ATOM   3712 H HD2  . ARG   A 1 246 ? 23.445 45.036 54.709 1   23.095 ? 755  ARG   A HD2  1 
ATOM   3713 H HD3  . ARG   A 1 246 ? 22.749 46.07  53.715 1   23.162 ? 755  ARG   A HD3  1 
ATOM   3714 H HE   . ARG   A 1 246 ? 21.379 44.431 55.479 1   26.239 ? 755  ARG   A HE   1 
ATOM   3715 H HH11 . ARG   A 1 246 ? 19.188 44.81  55.825 1   29.475 ? 755  ARG   A HH11 1 
ATOM   3716 H HH12 . ARG   A 1 246 ? 18.583 46.139 55.358 1   29.505 ? 755  ARG   A HH12 1 
ATOM   3717 H HH21 . ARG   A 1 246 ? 20.826 46.779 53.079 1   27.98  ? 755  ARG   A HH21 1 
ATOM   3718 H HH22 . ARG   A 1 246 ? 20.009 47.621 54.059 1   28.051 ? 755  ARG   A HH22 1 
ATOM   3719 N N    . SER   A 1 247 ? 24.494 44.048 49.051 1   11.528 ? 756  SER   A N    1 
ATOM   3720 C CA   . SER   A 1 247 ? 25.368 44.3   47.916 1   11.543 ? 756  SER   A CA   1 
ATOM   3721 C C    . SER   A 1 247 ? 24.667 45.28  46.98  1   10.402 ? 756  SER   A C    1 
ATOM   3722 O O    . SER   A 1 247 ? 23.447 45.489 47.055 1   10.951 ? 756  SER   A O    1 
ATOM   3723 C CB   . SER   A 1 247 ? 25.748 43.014 47.213 1   11.441 ? 756  SER   A CB   1 
ATOM   3724 O OG   . SER   A 1 247 ? 24.6   42.231 46.885 1   11.482 ? 756  SER   A OG   1 
ATOM   3725 H H    . SER   A 1 247 ? 23.644 44.384 49.034 1   12.11  ? 756  SER   A H    1 
ATOM   3726 H HA   . SER   A 1 247 ? 26.195 44.73  48.253 1   11.321 ? 756  SER   A HA   1 
ATOM   3727 H HB2  . SER   A 1 247 ? 26.233 43.228 46.395 1   11.508 ? 756  SER   A HB2  1 
ATOM   3728 H HB3  . SER   A 1 247 ? 26.341 42.494 47.787 1   11.495 ? 756  SER   A HB3  1 
ATOM   3729 H HG   . SER   A 1 247 ? 24.862 41.521 46.492 0   30     ? 756  SER   A HG   1 
ATOM   3730 N N    . GLY   A 1 248 ? 25.447 45.898 46.097 1   9.197  ? 757  GLY   A N    1 
ATOM   3731 C CA   . GLY   A 1 248 ? 24.897 46.902 45.21  1   9.178  ? 757  GLY   A CA   1 
ATOM   3732 C C    . GLY   A 1 248 ? 24.578 46.351 43.814 1   8.734  ? 757  GLY   A C    1 
ATOM   3733 O O    . GLY   A 1 248 ? 25.009 45.273 43.42  1   9.394  ? 757  GLY   A O    1 
ATOM   3734 H H    . GLY   A 1 248 ? 26.337 45.692 46.045 1   9.48   ? 757  GLY   A H    1 
ATOM   3735 H HA2  . GLY   A 1 248 ? 24.077 47.271 45.612 1   9.106  ? 757  GLY   A HA2  1 
ATOM   3736 H HA3  . GLY   A 1 248 ? 25.546 47.639 45.127 1   9.095  ? 757  GLY   A HA3  1 
ATOM   3737 N N    . PHE   A 1 249 ? 23.841 47.15  43.069 1   8.532  ? 758  PHE   A N    1 
ATOM   3738 C CA   . PHE   A 1 249 ? 23.749 47.039 41.624 1   9.351  ? 758  PHE   A CA   1 
ATOM   3739 C C    . PHE   A 1 249 ? 24.69  48.059 41.005 1   9.373  ? 758  PHE   A C    1 
ATOM   3740 O O    . PHE   A 1 249 ? 24.721 49.212 41.431 1   9.201  ? 758  PHE   A O    1 
ATOM   3741 C CB   . PHE   A 1 249 ? 22.35  47.365 41.115 1   8.966  ? 758  PHE   A CB   1 
ATOM   3742 C CG   . PHE   A 1 249 ? 21.255 46.387 41.499 1   9.281  ? 758  PHE   A CG   1 
ATOM   3743 C CD1  . PHE   A 1 249 ? 21.521 45.033 41.698 1   9.591  ? 758  PHE   A CD1  1 
ATOM   3744 C CD2  . PHE   A 1 249 ? 19.937 46.815 41.574 1   9.631  ? 758  PHE   A CD2  1 
ATOM   3745 C CE1  . PHE   A 1 249 ? 20.493 44.138 42.031 1   9.513  ? 758  PHE   A CE1  1 
ATOM   3746 C CE2  . PHE   A 1 249 ? 18.908 45.929 41.877 1   9.158  ? 758  PHE   A CE2  1 
ATOM   3747 C CZ   . PHE   A 1 249 ? 19.187 44.592 42.128 1   8.756  ? 758  PHE   A CZ   1 
ATOM   3748 H H    . PHE   A 1 249 ? 23.36  47.809 43.482 1   8.766  ? 758  PHE   A H    1 
ATOM   3749 H HA   . PHE   A 1 249 ? 24.008 46.127 41.341 1   9.136  ? 758  PHE   A HA   1 
ATOM   3750 H HB2  . PHE   A 1 249 ? 22.103 48.257 41.446 1   9.126  ? 758  PHE   A HB2  1 
ATOM   3751 H HB3  . PHE   A 1 249 ? 22.387 47.419 40.134 1   9.125  ? 758  PHE   A HB3  1 
ATOM   3752 H HD1  . PHE   A 1 249 ? 22.41  44.72  41.647 1   9.486  ? 758  PHE   A HD1  1 
ATOM   3753 H HD2  . PHE   A 1 249 ? 19.736 47.724 41.416 1   9.43   ? 758  PHE   A HD2  1 
ATOM   3754 H HE1  . PHE   A 1 249 ? 20.69  43.228 42.186 1   9.346  ? 758  PHE   A HE1  1 
ATOM   3755 H HE2  . PHE   A 1 249 ? 18.022 46.246 41.95  1   9.178  ? 758  PHE   A HE2  1 
ATOM   3756 H HZ   . PHE   A 1 249 ? 18.489 43.992 42.338 1   9.03   ? 758  PHE   A HZ   1 
ATOM   3757 N N    . GLY   A 1 250 ? 25.393 47.628 39.956 1   9.573  ? 759  GLY   A N    1 
ATOM   3758 C CA   . GLY   A 1 250 ? 26.277 48.504 39.227 1   9.237  ? 759  GLY   A CA   1 
ATOM   3759 C C    . GLY   A 1 250 ? 26.12  48.387 37.713 1   9.418  ? 759  GLY   A C    1 
ATOM   3760 O O    . GLY   A 1 250 ? 25.599 47.402 37.188 1   9.126  ? 759  GLY   A O    1 
ATOM   3761 H H    . GLY   A 1 250 ? 25.317 46.758 39.688 1   9.445  ? 759  GLY   A H    1 
ATOM   3762 H HA2  . GLY   A 1 250 ? 26.104 49.435 39.499 1   9.365  ? 759  GLY   A HA2  1 
ATOM   3763 H HA3  . GLY   A 1 250 ? 27.208 48.29  39.472 1   9.371  ? 759  GLY   A HA3  1 
ATOM   3764 N N    . ILE   A 1 251 ? 26.621 49.436 37.048 1   10.179 ? 760  ILE   A N    1 
ATOM   3765 C CA   . ILE   A 1 251 ? 26.865 49.426 35.619 1   11.687 ? 760  ILE   A CA   1 
ATOM   3766 C C    . ILE   A 1 251 ? 28.123 48.594 35.379 1   12.228 ? 760  ILE   A C    1 
ATOM   3767 O O    . ILE   A 1 251 ? 29.11  48.703 36.112 1   11.751 ? 760  ILE   A O    1 
ATOM   3768 C CB   . ILE   A 1 251 ? 27.002 50.85  35.06  1   12.971 ? 760  ILE   A CB   1 
ATOM   3769 C CG1  . ILE   A 1 251 ? 25.825 51.72  35.443 1   14.511 ? 760  ILE   A CG1  1 
ATOM   3770 C CG2  . ILE   A 1 251 ? 27.22  50.85  33.538 1   13.475 ? 760  ILE   A CG2  1 
ATOM   3771 C CD1  . ILE   A 1 251 ? 24.481 51.246 34.928 1   14.971 ? 760  ILE   A CD1  1 
ATOM   3772 H H    . ILE   A 1 251 ? 26.835 50.189 37.519 1   10.359 ? 760  ILE   A H    1 
ATOM   3773 H HA   . ILE   A 1 251 ? 26.111 48.991 35.179 1   11.702 ? 760  ILE   A HA   1 
ATOM   3774 H HB   . ILE   A 1 251 ? 27.797 51.245 35.469 1   13.088 ? 760  ILE   A HB   1 
ATOM   3775 H HG12 . ILE   A 1 251 ? 25.781 51.779 36.419 1   14.181 ? 760  ILE   A HG12 1 
ATOM   3776 H HG13 . ILE   A 1 251 ? 25.985 52.623 35.101 1   14.225 ? 760  ILE   A HG13 1 
ATOM   3777 H HG21 . ILE   A 1 251 ? 27.084 51.747 33.189 1   13.336 ? 760  ILE   A HG21 1 
ATOM   3778 H HG22 . ILE   A 1 251 ? 26.589 50.243 33.117 1   13.325 ? 760  ILE   A HG22 1 
ATOM   3779 H HG23 . ILE   A 1 251 ? 28.127 50.562 33.337 1   13.323 ? 760  ILE   A HG23 1 
ATOM   3780 H HD11 . ILE   A 1 251 ? 24.525 51.109 33.963 1   14.773 ? 760  ILE   A HD11 1 
ATOM   3781 H HD12 . ILE   A 1 251 ? 23.803 51.919 35.127 1   14.812 ? 760  ILE   A HD12 1 
ATOM   3782 H HD13 . ILE   A 1 251 ? 24.238 50.407 35.363 1   14.78  ? 760  ILE   A HD13 1 
ATOM   3783 N N    . GLY   A 1 252 ? 28.079 47.775 34.329 1   11.926 ? 761  GLY   A N    1 
ATOM   3784 C CA   . GLY   A 1 252 ? 29.173 46.88  34.015 1   11.92  ? 761  GLY   A CA   1 
ATOM   3785 C C    . GLY   A 1 252 ? 29.849 47.323 32.718 1   12.213 ? 761  GLY   A C    1 
ATOM   3786 O O    . GLY   A 1 252 ? 29.17  47.688 31.758 1   10.985 ? 761  GLY   A O    1 
ATOM   3787 H H    . GLY   A 1 252 ? 27.343 47.775 33.787 1   11.991 ? 761  GLY   A H    1 
ATOM   3788 H HA2  . GLY   A 1 252 ? 29.825 46.881 34.753 1   12.013 ? 761  GLY   A HA2  1 
ATOM   3789 H HA3  . GLY   A 1 252 ? 28.825 45.963 33.914 1   11.991 ? 761  GLY   A HA3  1 
ATOM   3790 N N    . MET   A 1 253 ? 31.186 47.301 32.726 1   13.095 ? 762  MET   A N    1 
ATOM   3791 C CA   . MET   A 1 253 ? 31.996 47.705 31.585 1   14.596 ? 762  MET   A CA   1 
ATOM   3792 C C    . MET   A 1 253 ? 33.24  46.827 31.568 1   13.935 ? 762  MET   A C    1 
ATOM   3793 O O    . MET   A 1 253 ? 33.633 46.283 32.591 1   12.796 ? 762  MET   A O    1 
ATOM   3794 C CB   . MET   A 1 253 ? 32.472 49.165 31.696 1   17.138 ? 762  MET   A CB   1 
ATOM   3795 C CG   . MET   A 1 253 ? 31.387 50.237 31.677 1   18.619 ? 762  MET   A CG   1 
ATOM   3796 S SD   . MET   A 1 253 ? 31.782 51.671 32.709 1   18.796 ? 762  MET   A SD   1 
ATOM   3797 C CE   . MET   A 1 253 ? 31.423 50.995 34.338 1   19.402 ? 762  MET   A CE   1 
ATOM   3798 H H    . MET   A 1 253 ? 31.615 47.019 33.482 1   13.184 ? 762  MET   A H    1 
ATOM   3799 H HA   . MET   A 1 253 ? 31.481 47.573 30.749 1   14.531 ? 762  MET   A HA   1 
ATOM   3800 H HB2  . MET   A 1 253 ? 32.981 49.255 32.53  1   16.829 ? 762  MET   A HB2  1 
ATOM   3801 H HB3  . MET   A 1 253 ? 33.092 49.34  30.956 1   16.821 ? 762  MET   A HB3  1 
ATOM   3802 H HG2  . MET   A 1 253 ? 31.253 50.542 30.757 1   18.261 ? 762  MET   A HG2  1 
ATOM   3803 H HG3  . MET   A 1 253 ? 30.547 49.853 31.988 1   18.161 ? 762  MET   A HG3  1 
ATOM   3804 H HE1  . MET   A 1 253 ? 31.594 51.675 35.016 1   19.249 ? 762  MET   A HE1  1 
ATOM   3805 H HE2  . MET   A 1 253 ? 30.487 50.725 34.378 1   19.249 ? 762  MET   A HE2  1 
ATOM   3806 H HE3  . MET   A 1 253 ? 31.993 50.222 34.502 1   19.249 ? 762  MET   A HE3  1 
ATOM   3807 N N    . ARG   A 1 254 ? 33.888 46.723 30.398 1   15.122 ? 763  ARG   A N    1 
ATOM   3808 C CA   . ARG   A 1 254 ? 35.115 45.957 30.286 1   14.916 ? 763  ARG   A CA   1 
ATOM   3809 C C    . ARG   A 1 254 ? 36.214 46.564 31.17  1   16.856 ? 763  ARG   A C    1 
ATOM   3810 O O    . ARG   A 1 254 ? 36.167 47.745 31.509 1   17.465 ? 763  ARG   A O    1 
ATOM   3811 C CB   . ARG   A 1 254 ? 35.511 45.853 28.804 1   15.486 ? 763  ARG   A CB   1 
ATOM   3812 C CG   . ARG   A 1 254 ? 34.787 44.75  28.037 1   15.68  ? 763  ARG   A CG   1 
ATOM   3813 C CD   . ARG   A 1 254 ? 35.354 44.534 26.608 1   17.023 ? 763  ARG   A CD   1 
ATOM   3814 N NE   . ARG   A 1 254 ? 35.123 45.721 25.775 1   17.841 ? 763  ARG   A NE   1 
ATOM   3815 C CZ   . ARG   A 1 254 ? 33.961 46.035 25.233 1   18.057 ? 763  ARG   A CZ   1 
ATOM   3816 N NH1  . ARG   A 1 254 ? 32.94  45.194 25.286 1   19.034 ? 763  ARG   A NH1  1 
ATOM   3817 N NH2  . ARG   A 1 254 ? 33.82  47.201 24.654 1   17.946 ? 763  ARG   A NH2  1 
ATOM   3818 H H    . ARG   A 1 254 ? 33.552 47.139 29.656 1   14.791 ? 763  ARG   A H    1 
ATOM   3819 H HA   . ARG   A 1 254 ? 34.93  45.041 30.614 1   15.437 ? 763  ARG   A HA   1 
ATOM   3820 H HB2  . ARG   A 1 254 ? 35.333 46.712 28.366 1   15.407 ? 763  ARG   A HB2  1 
ATOM   3821 H HB3  . ARG   A 1 254 ? 36.477 45.688 28.749 1   15.408 ? 763  ARG   A HB3  1 
ATOM   3822 H HG2  . ARG   A 1 254 ? 34.86  43.909 28.538 1   15.927 ? 763  ARG   A HG2  1 
ATOM   3823 H HG3  . ARG   A 1 254 ? 33.835 44.978 27.972 1   15.952 ? 763  ARG   A HG3  1 
ATOM   3824 H HD2  . ARG   A 1 254 ? 36.316 44.359 26.662 1   16.909 ? 763  ARG   A HD2  1 
ATOM   3825 H HD3  . ARG   A 1 254 ? 34.926 43.757 26.195 1   16.928 ? 763  ARG   A HD3  1 
ATOM   3826 H HE   . ARG   A 1 254 ? 35.798 46.251 25.627 1   17.704 ? 763  ARG   A HE   1 
ATOM   3827 H HH11 . ARG   A 1 254 ? 32.798 44.7   26.003 1   18.651 ? 763  ARG   A HH11 1 
ATOM   3828 H HH12 . ARG   A 1 254 ? 32.389 45.141 24.598 1   18.686 ? 763  ARG   A HH12 1 
ATOM   3829 H HH21 . ARG   A 1 254 ? 34.305 47.89  24.925 1   17.98  ? 763  ARG   A HH21 1 
ATOM   3830 H HH22 . ARG   A 1 254 ? 33.238 47.296 23.995 1   17.992 ? 763  ARG   A HH22 1 
ATOM   3831 N N    . LYS   A 1 255 ? 37.217 45.749 31.528 1   20.214 ? 764  LYS   A N    1 
ATOM   3832 C CA   . LYS   A 1 255 ? 38.375 46.23  32.285 1   23.614 ? 764  LYS   A CA   1 
ATOM   3833 C C    . LYS   A 1 255 ? 39.052 47.39  31.544 1   23.733 ? 764  LYS   A C    1 
ATOM   3834 O O    . LYS   A 1 255 ? 39.052 47.44  30.318 1   20.622 ? 764  LYS   A O    1 
ATOM   3835 C CB   . LYS   A 1 255 ? 39.412 45.116 32.495 1   26.118 ? 764  LYS   A CB   1 
ATOM   3836 C CG   . LYS   A 1 255 ? 39.106 44.025 33.503 1   27.346 ? 764  LYS   A CG   1 
ATOM   3837 C CD   . LYS   A 1 255 ? 38.896 44.577 34.906 1   31.264 ? 764  LYS   A CD   1 
ATOM   3838 C CE   . LYS   A 1 255 ? 39.089 43.545 35.961 1   33.055 ? 764  LYS   A CE   1 
ATOM   3839 N NZ   . LYS   A 1 255 ? 38.943 44.071 37.308 1   31.738 ? 764  LYS   A NZ   1 
ATOM   3840 H H    . LYS   A 1 255 ? 37.181 44.866 31.294 1   19.996 ? 764  LYS   A H    1 
ATOM   3841 H HA   . LYS   A 1 255 ? 38.058 46.553 33.166 1   23.434 ? 764  LYS   A HA   1 
ATOM   3842 H HB2  . LYS   A 1 255 ? 39.567 44.686 31.628 1   25.864 ? 764  LYS   A HB2  1 
ATOM   3843 H HB3  . LYS   A 1 255 ? 40.256 45.539 32.762 1   25.8   ? 764  LYS   A HB3  1 
ATOM   3844 H HG2  . LYS   A 1 255 ? 38.297 43.548 33.218 1   27.828 ? 764  LYS   A HG2  1 
ATOM   3845 H HG3  . LYS   A 1 255 ? 39.851 43.385 33.514 1   27.933 ? 764  LYS   A HG3  1 
ATOM   3846 H HD2  . LYS   A 1 255 ? 39.528 45.312 35.058 1   30.721 ? 764  LYS   A HD2  1 
ATOM   3847 H HD3  . LYS   A 1 255 ? 37.986 44.939 34.975 1   30.734 ? 764  LYS   A HD3  1 
ATOM   3848 H HE2  . LYS   A 1 255 ? 38.439 42.831 35.832 1   32.315 ? 764  LYS   A HE2  1 
ATOM   3849 H HE3  . LYS   A 1 255 ? 39.978 43.158 35.872 1   32.291 ? 764  LYS   A HE3  1 
ATOM   3850 H HZ1  . LYS   A 1 255 ? 38.252 44.657 37.336 1   32.123 ? 764  LYS   A HZ1  1 
ATOM   3851 H HZ2  . LYS   A 1 255 ? 39.703 44.498 37.552 1   32.134 ? 764  LYS   A HZ2  1 
ATOM   3852 H HZ3  . LYS   A 1 255 ? 38.775 43.391 37.882 1   32.134 ? 764  LYS   A HZ3  1 
ATOM   3853 N N    . ASP   A 1 256 ? 39.562 48.352 32.318 1   27.397 ? 765  ASP   A N    1 
ATOM   3854 C CA   . ASP   A 1 256 ? 40.26  49.531 31.823 1   33.68  ? 765  ASP   A CA   1 
ATOM   3855 C C    . ASP   A 1 256 ? 39.418 50.29  30.811 1   35.331 ? 765  ASP   A C    1 
ATOM   3856 O O    . ASP   A 1 256 ? 39.937 50.888 29.864 1   35.739 ? 765  ASP   A O    1 
ATOM   3857 C CB   . ASP   A 1 256 ? 41.617 49.179 31.239 1   39.343 ? 765  ASP   A CB   1 
ATOM   3858 C CG   . ASP   A 1 256 ? 42.45  48.259 32.11  1   41.089 ? 765  ASP   A CG   1 
ATOM   3859 O OD1  . ASP   A 1 256 ? 42.421 48.436 33.36  1   38.368 ? 765  ASP   A OD1  1 
ATOM   3860 O OD2  . ASP   A 1 256 ? 43.12  47.389 31.529 1   47.036 ? 765  ASP   A OD2  1 
ATOM   3861 H H    . ASP   A 1 256 ? 39.477 48.261 33.223 1   27.719 ? 765  ASP   A H    1 
ATOM   3862 H HA   . ASP   A 1 256 ? 40.425 50.126 32.589 1   33.605 ? 765  ASP   A HA   1 
ATOM   3863 H HB2  . ASP   A 1 256 ? 41.487 48.746 30.37  1   38.369 ? 765  ASP   A HB2  1 
ATOM   3864 H HB3  . ASP   A 1 256 ? 42.124 50.005 31.095 1   38.343 ? 765  ASP   A HB3  1 
ATOM   3865 N N    . SER   A 1 257 ? 38.104 50.291 31.044 1   33.057 ? 766  SER   A N    1 
ATOM   3866 C CA   . SER   A 1 257 ? 37.196 51.015 30.181 1   29.449 ? 766  SER   A CA   1 
ATOM   3867 C C    . SER   A 1 257 ? 37.398 52.506 30.409 1   29.043 ? 766  SER   A C    1 
ATOM   3868 O O    . SER   A 1 257 ? 37.448 52.95  31.561 1   29.178 ? 766  SER   A O    1 
ATOM   3869 C CB   . SER   A 1 257 ? 35.781 50.602 30.439 1   28.117 ? 766  SER   A CB   1 
ATOM   3870 O OG   . SER   A 1 257 ? 34.876 51.404 29.709 1   28.302 ? 766  SER   A OG   1 
ATOM   3871 H H    . SER   A 1 257 ? 37.767 49.845 31.767 1   32.555 ? 766  SER   A H    1 
ATOM   3872 H HA   . SER   A 1 257 ? 37.423 50.801 29.242 1   29.887 ? 766  SER   A HA   1 
ATOM   3873 H HB2  . SER   A 1 257 ? 35.666 49.67  30.179 1   28.374 ? 766  SER   A HB2  1 
ATOM   3874 H HB3  . SER   A 1 257 ? 35.589 50.681 31.393 1   28.467 ? 766  SER   A HB3  1 
ATOM   3875 H HG   . SER   A 1 257 ? 34.084 51.136 29.895 0   30     ? 766  SER   A HG   1 
ATOM   3876 N N    . PRO   A 1 258 ? 37.443 53.318 29.331 1   28.801 ? 767  PRO   A N    1 
ATOM   3877 C CA   . PRO   A 1 258 ? 37.544 54.758 29.477 1   31.445 ? 767  PRO   A CA   1 
ATOM   3878 C C    . PRO   A 1 258 ? 36.24  55.405 29.943 1   29.743 ? 767  PRO   A C    1 
ATOM   3879 O O    . PRO   A 1 258 ? 36.221 56.6   30.179 1   30.227 ? 767  PRO   A O    1 
ATOM   3880 C CB   . PRO   A 1 258 ? 37.918 55.235 28.075 1   31.614 ? 767  PRO   A CB   1 
ATOM   3881 C CG   . PRO   A 1 258 ? 37.198 54.215 27.183 1   34.971 ? 767  PRO   A CG   1 
ATOM   3882 C CD   . PRO   A 1 258 ? 37.298 52.9   27.923 1   33.447 ? 767  PRO   A CD   1 
ATOM   3883 H HA   . PRO   A 1 258 ? 38.264 54.976 30.106 1   30.614 ? 767  PRO   A HA   1 
ATOM   3884 H HB2  . PRO   A 1 258 ? 37.593 56.141 27.91  1   32.27  ? 767  PRO   A HB2  1 
ATOM   3885 H HB3  . PRO   A 1 258 ? 38.885 55.204 27.938 1   32.291 ? 767  PRO   A HB3  1 
ATOM   3886 H HG2  . PRO   A 1 258 ? 36.262 54.466 27.053 1   33.847 ? 767  PRO   A HG2  1 
ATOM   3887 H HG3  . PRO   A 1 258 ? 37.632 54.151 26.308 1   33.847 ? 767  PRO   A HG3  1 
ATOM   3888 H HD2  . PRO   A 1 258 ? 36.491 52.363 27.8   1   32.565 ? 767  PRO   A HD2  1 
ATOM   3889 H HD3  . PRO   A 1 258 ? 38.076 52.386 27.632 1   32.595 ? 767  PRO   A HD3  1 
ATOM   3890 N N    . TRP   A 1 259 ? 35.156 54.623 30.068 1   29.88  ? 768  TRP   A N    1 
ATOM   3891 C CA   . TRP   A 1 259 ? 33.869 55.144 30.511 1   29.393 ? 768  TRP   A CA   1 
ATOM   3892 C C    . TRP   A 1 259 ? 33.721 55.13  32.034 1   23.84  ? 768  TRP   A C    1 
ATOM   3893 O O    . TRP   A 1 259 ? 32.966 55.923 32.569 1   20.674 ? 768  TRP   A O    1 
ATOM   3894 C CB   . TRP   A 1 259 ? 32.717 54.346 29.875 1   33.059 ? 768  TRP   A CB   1 
ATOM   3895 C CG   . TRP   A 1 259 ? 32.791 54.274 28.37  1   39.051 ? 768  TRP   A CG   1 
ATOM   3896 C CD1  . TRP   A 1 259 ? 33.35  53.274 27.631 1   39.715 ? 768  TRP   A CD1  1 
ATOM   3897 C CD2  . TRP   A 1 259 ? 32.303 55.248 27.422 1   42.371 ? 768  TRP   A CD2  1 
ATOM   3898 N NE1  . TRP   A 1 259 ? 33.272 53.569 26.295 1   42.343 ? 768  TRP   A NE1  1 
ATOM   3899 C CE2  . TRP   A 1 259 ? 32.623 54.762 26.134 1   43.475 ? 768  TRP   A CE2  1 
ATOM   3900 C CE3  . TRP   A 1 259 ? 31.616 56.461 27.525 1   47.227 ? 768  TRP   A CE3  1 
ATOM   3901 C CZ2  . TRP   A 1 259 ? 32.286 55.453 24.97  1   48.163 ? 768  TRP   A CZ2  1 
ATOM   3902 C CZ3  . TRP   A 1 259 ? 31.258 57.13  26.37  1   51.859 ? 768  TRP   A CZ3  1 
ATOM   3903 C CH2  . TRP   A 1 259 ? 31.595 56.636 25.109 1   49.651 ? 768  TRP   A CH2  1 
ATOM   3904 H H    . TRP   A 1 259 ? 35.215 53.736 29.857 1   29.797 ? 768  TRP   A H    1 
ATOM   3905 H HA   . TRP   A 1 259 ? 33.794 56.086 30.201 1   29.001 ? 768  TRP   A HA   1 
ATOM   3906 H HB2  . TRP   A 1 259 ? 32.729 53.435 30.239 1   33.457 ? 768  TRP   A HB2  1 
ATOM   3907 H HB3  . TRP   A 1 259 ? 31.868 54.766 30.132 1   33.457 ? 768  TRP   A HB3  1 
ATOM   3908 H HD1  . TRP   A 1 259 ? 33.776 52.512 27.979 1   40.06  ? 768  TRP   A HD1  1 
ATOM   3909 H HE1  . TRP   A 1 259 ? 33.566 53.061 25.649 1   41.965 ? 768  TRP   A HE1  1 
ATOM   3910 H HE3  . TRP   A 1 259 ? 31.377 56.798 28.367 1   46.697 ? 768  TRP   A HE3  1 
ATOM   3911 H HZ2  . TRP   A 1 259 ? 32.504 55.11  24.12  1   47.162 ? 768  TRP   A HZ2  1 
ATOM   3912 H HZ3  . TRP   A 1 259 ? 30.799 57.948 26.433 1   50.083 ? 768  TRP   A HZ3  1 
ATOM   3913 H HH2  . TRP   A 1 259 ? 31.356 57.124 24.341 1   49.669 ? 768  TRP   A HH2  1 
ATOM   3914 N N    . LYS   A 1 260 ? 34.413 54.223 32.726 1   22.095 ? 769  LYS   A N    1 
ATOM   3915 C CA   . LYS   A 1 260 ? 34.124 53.899 34.118 1   21.848 ? 769  LYS   A CA   1 
ATOM   3916 C C    . LYS   A 1 260 ? 34.082 55.132 35.025 1   18.682 ? 769  LYS   A C    1 
ATOM   3917 O O    . LYS   A 1 260 ? 33.165 55.257 35.833 1   17.027 ? 769  LYS   A O    1 
ATOM   3918 C CB   . LYS   A 1 260 ? 35.115 52.865 34.673 1   23.881 ? 769  LYS   A CB   1 
ATOM   3919 C CG   . LYS   A 1 260 ? 34.823 52.459 36.127 1   27.888 ? 769  LYS   A CG   1 
ATOM   3920 C CD   . LYS   A 1 260 ? 35.956 51.716 36.823 1   32.078 ? 769  LYS   A CD   1 
ATOM   3921 C CE   . LYS   A 1 260 ? 35.824 51.778 38.316 1   36.819 ? 769  LYS   A CE   1 
ATOM   3922 N NZ   . LYS   A 1 260 ? 36.338 50.56  38.962 1   44.435 ? 769  LYS   A NZ   1 
ATOM   3923 H H    . LYS   A 1 260 ? 35.1   53.784 32.314 1   22.539 ? 769  LYS   A H    1 
ATOM   3924 H HA   . LYS   A 1 260 ? 33.227 53.483 34.145 1   21.579 ? 769  LYS   A HA   1 
ATOM   3925 H HB2  . LYS   A 1 260 ? 35.088 52.061 34.111 1   24.254 ? 769  LYS   A HB2  1 
ATOM   3926 H HB3  . LYS   A 1 260 ? 36.022 53.235 34.626 1   24.29  ? 769  LYS   A HB3  1 
ATOM   3927 H HG2  . LYS   A 1 260 ? 34.616 53.267 36.642 1   27.758 ? 769  LYS   A HG2  1 
ATOM   3928 H HG3  . LYS   A 1 260 ? 34.022 51.891 36.134 1   27.791 ? 769  LYS   A HG3  1 
ATOM   3929 H HD2  . LYS   A 1 260 ? 35.949 50.776 36.538 1   32.216 ? 769  LYS   A HD2  1 
ATOM   3930 H HD3  . LYS   A 1 260 ? 36.815 52.112 36.559 1   32.053 ? 769  LYS   A HD3  1 
ATOM   3931 H HE2  . LYS   A 1 260 ? 36.317 52.547 38.654 1   37.253 ? 769  LYS   A HE2  1 
ATOM   3932 H HE3  . LYS   A 1 260 ? 34.887 51.89  38.557 1   37.065 ? 769  LYS   A HE3  1 
ATOM   3933 H HZ1  . LYS   A 1 260 ? 37.186 50.401 38.685 1   41.852 ? 769  LYS   A HZ1  1 
ATOM   3934 H HZ2  . LYS   A 1 260 ? 35.815 49.853 38.742 1   41.844 ? 769  LYS   A HZ2  1 
ATOM   3935 H HZ3  . LYS   A 1 260 ? 36.333 50.665 39.862 1   41.901 ? 769  LYS   A HZ3  1 
ATOM   3936 N N    . GLN   A 1 261 ? 35.091 56.004 34.962 1   18.468 ? 770  GLN   A N    1 
ATOM   3937 C CA   . GLN   A 1 261 ? 35.199 57.085 35.936 1   18.409 ? 770  GLN   A CA   1 
ATOM   3938 C C    . GLN   A 1 261 ? 34.006 58.03  35.78  1   17.06  ? 770  GLN   A C    1 
ATOM   3939 O O    . GLN   A 1 261 ? 33.38  58.436 36.767 1   16.414 ? 770  GLN   A O    1 
ATOM   3940 C CB   . GLN   A 1 261 ? 36.534 57.844 35.891 1   19.091 ? 770  GLN   A CB   1 
ATOM   3941 H H    . GLN   A 1 261 ? 35.723 55.926 34.306 1   18.549 ? 770  GLN   A H    1 
ATOM   3942 H HA   . GLN   A 1 261 ? 35.138 56.678 36.837 1   18.282 ? 770  GLN   A HA   1 
ATOM   3943 H HB2  . GLN   A 1 261 ? 37.261 57.171 35.93  0   30     ? 770  GLN   A HB2  1 
ATOM   3944 H HB3  . GLN   A 1 261 ? 36.362 58.793 35.834 0   30     ? 770  GLN   A HB3  1 
ATOM   3945 N N    . ASN   A 1 262 ? 33.651 58.343 34.534 1   15.266 ? 771  ASN   A N    1 
ATOM   3946 C CA   . ASN   A 1 262 ? 32.568 59.268 34.275 1   16.142 ? 771  ASN   A CA   1 
ATOM   3947 C C    . ASN   A 1 262 ? 31.211 58.627 34.571 1   14.747 ? 771  ASN   A C    1 
ATOM   3948 O O    . ASN   A 1 262 ? 30.272 59.313 34.971 1   13.334 ? 771  ASN   A O    1 
ATOM   3949 C CB   . ASN   A 1 262 ? 32.671 59.817 32.864 1   18.321 ? 771  ASN   A CB   1 
ATOM   3950 C CG   . ASN   A 1 262 ? 33.782 60.834 32.742 1   21.392 ? 771  ASN   A CG   1 
ATOM   3951 O OD1  . ASN   A 1 262 ? 34.326 61.333 33.737 1   23.796 ? 771  ASN   A OD1  1 
ATOM   3952 N ND2  . ASN   A 1 262 ? 34.13  61.165 31.523 1   23.297 ? 771  ASN   A ND2  1 
ATOM   3953 H H    . ASN   A 1 262 ? 34.099 57.974 33.828 1   15.941 ? 771  ASN   A H    1 
ATOM   3954 H HA   . ASN   A 1 262 ? 32.673 60.029 34.888 1   16.169 ? 771  ASN   A HA   1 
ATOM   3955 H HB2  . ASN   A 1 262 ? 32.838 59.081 32.242 1   18.475 ? 771  ASN   A HB2  1 
ATOM   3956 H HB3  . ASN   A 1 262 ? 31.823 60.236 32.618 1   18.429 ? 771  ASN   A HB3  1 
ATOM   3957 H HD21 . ASN   A 1 262 ? 34.852 61.662 31.388 1   22.693 ? 771  ASN   A HD21 1 
ATOM   3958 H HD22 . ASN   A 1 262 ? 33.644 60.892 30.832 1   22.66  ? 771  ASN   A HD22 1 
ATOM   3959 N N    . VAL   A 1 263 ? 31.1   57.311 34.379 1   12.743 ? 772  VAL   A N    1 
ATOM   3960 C CA   . VAL   A 1 263 ? 29.865 56.643 34.769 1   13.485 ? 772  VAL   A CA   1 
ATOM   3961 C C    . VAL   A 1 263 ? 29.689 56.763 36.287 1   12.2   ? 772  VAL   A C    1 
ATOM   3962 O O    . VAL   A 1 263 ? 28.603 57.114 36.764 1   12.489 ? 772  VAL   A O    1 
ATOM   3963 C CB   . VAL   A 1 263 ? 29.797 55.181 34.305 1   13.516 ? 772  VAL   A CB   1 
ATOM   3964 C CG1  . VAL   A 1 263 ? 28.683 54.4   34.997 1   14.073 ? 772  VAL   A CG1  1 
ATOM   3965 C CG2  . VAL   A 1 263 ? 29.652 55.107 32.8   1   15.416 ? 772  VAL   A CG2  1 
ATOM   3966 H H    . VAL   A 1 263 ? 31.778 56.829 34.002 1   13.394 ? 772  VAL   A H    1 
ATOM   3967 H HA   . VAL   A 1 263 ? 29.125 57.121 34.346 1   13.119 ? 772  VAL   A HA   1 
ATOM   3968 H HB   . VAL   A 1 263 ? 30.655 54.76  34.546 1   13.952 ? 772  VAL   A HB   1 
ATOM   3969 H HG11 . VAL   A 1 263 ? 27.868 54.929 34.998 1   13.891 ? 772  VAL   A HG11 1 
ATOM   3970 H HG12 . VAL   A 1 263 ? 28.942 54.204 35.912 1   13.865 ? 772  VAL   A HG12 1 
ATOM   3971 H HG13 . VAL   A 1 263 ? 28.527 53.567 34.52  1   13.909 ? 772  VAL   A HG13 1 
ATOM   3972 H HG21 . VAL   A 1 263 ? 29.659 54.177 32.517 1   14.841 ? 772  VAL   A HG21 1 
ATOM   3973 H HG22 . VAL   A 1 263 ? 30.389 55.578 32.378 1   14.916 ? 772  VAL   A HG22 1 
ATOM   3974 H HG23 . VAL   A 1 263 ? 28.812 55.519 32.534 1   14.846 ? 772  VAL   A HG23 1 
ATOM   3975 N N    . SER   A 1 264 ? 30.749 56.464 37.038 1   12.36  ? 773  SER   A N    1 
ATOM   3976 C CA   . SER   A 1 264 ? 30.698 56.566 38.495 1   12.659 ? 773  SER   A CA   1 
ATOM   3977 C C    . SER   A 1 264 ? 30.38  57.994 38.937 1   13.57  ? 773  SER   A C    1 
ATOM   3978 O O    . SER   A 1 264 ? 29.612 58.22  39.884 1   11.669 ? 773  SER   A O    1 
ATOM   3979 C CB   . SER   A 1 264 ? 31.96  56.056 39.128 1   12.504 ? 773  SER   A CB   1 
ATOM   3980 O OG   . SER   A 1 264 ? 31.97  54.634 39.18  1   12.558 ? 773  SER   A OG   1 
ATOM   3981 H H    . SER   A 1 264 ? 31.522 56.182 36.64  1   12.399 ? 773  SER   A H    1 
ATOM   3982 H HA   . SER   A 1 264 ? 29.955 55.989 38.805 1   12.728 ? 773  SER   A HA   1 
ATOM   3983 H HB2  . SER   A 1 264 ? 32.728 56.368 38.613 1   12.552 ? 773  SER   A HB2  1 
ATOM   3984 H HB3  . SER   A 1 264 ? 32.035 56.413 40.033 1   12.557 ? 773  SER   A HB3  1 
ATOM   3985 H HG   . SER   A 1 264 ? 32.687 54.376 39.538 0   30     ? 773  SER   A HG   1 
ATOM   3986 N N    . LEU   A 1 265 ? 30.942 58.984 38.231 1   14.001 ? 774  LEU   A N    1 
ATOM   3987 C CA   . LEU   A 1 265 ? 30.681 60.378 38.573 1   15.073 ? 774  LEU   A CA   1 
ATOM   3988 C C    . LEU   A 1 265 ? 29.202 60.733 38.385 1   14.217 ? 774  LEU   A C    1 
ATOM   3989 O O    . LEU   A 1 265 ? 28.613 61.512 39.131 1   13.974 ? 774  LEU   A O    1 
ATOM   3990 C CB   . LEU   A 1 265 ? 31.587 61.278 37.728 1   18.803 ? 774  LEU   A CB   1 
ATOM   3991 C CG   . LEU   A 1 265 ? 32.939 61.613 38.361 1   24.958 ? 774  LEU   A CG   1 
ATOM   3992 C CD1  . LEU   A 1 265 ? 33.937 62.209 37.369 1   27.882 ? 774  LEU   A CD1  1 
ATOM   3993 C CD2  . LEU   A 1 265 ? 32.704 62.591 39.512 1   26.791 ? 774  LEU   A CD2  1 
ATOM   3994 H H    . LEU   A 1 265 ? 31.501 58.79  37.534 1   14.172 ? 774  LEU   A H    1 
ATOM   3995 H HA   . LEU   A 1 265 ? 30.905 60.501 39.528 1   15.478 ? 774  LEU   A HA   1 
ATOM   3996 H HB2  . LEU   A 1 265 ? 31.746 60.837 36.862 1   18.975 ? 774  LEU   A HB2  1 
ATOM   3997 H HB3  . LEU   A 1 265 ? 31.108 62.121 37.552 1   19.059 ? 774  LEU   A HB3  1 
ATOM   3998 H HG   . LEU   A 1 265 ? 33.325 60.782 38.733 1   24.49  ? 774  LEU   A HG   1 
ATOM   3999 H HD11 . LEU   A 1 265 ? 34.101 61.573 36.652 1   26.989 ? 774  LEU   A HD11 1 
ATOM   4000 H HD12 . LEU   A 1 265 ? 34.773 62.403 37.825 1   26.989 ? 774  LEU   A HD12 1 
ATOM   4001 H HD13 . LEU   A 1 265 ? 33.574 63.029 36.995 1   26.989 ? 774  LEU   A HD13 1 
ATOM   4002 H HD21 . LEU   A 1 265 ? 32.086 62.203 40.153 1   26.08  ? 774  LEU   A HD21 1 
ATOM   4003 H HD22 . LEU   A 1 265 ? 32.33  63.418 39.163 1   26.236 ? 774  LEU   A HD22 1 
ATOM   4004 H HD23 . LEU   A 1 265 ? 33.549 62.782 39.953 1   26.208 ? 774  LEU   A HD23 1 
ATOM   4005 N N    . SER   A 1 266 ? 28.606 60.221 37.322 1   14.722 ? 775  SER   A N    1 
ATOM   4006 C CA   . SER   A 1 266 ? 27.204 60.463 37.043 1   13.354 ? 775  SER   A CA   1 
ATOM   4007 C C    . SER   A 1 266 ? 26.32  59.873 38.142 1   12.249 ? 775  SER   A C    1 
ATOM   4008 O O    . SER   A 1 266 ? 25.351 60.49  38.583 1   11.855 ? 775  SER   A O    1 
ATOM   4009 C CB   . SER   A 1 266 ? 26.859 59.893 35.687 1   14.254 ? 775  SER   A CB   1 
ATOM   4010 O OG   . SER   A 1 266 ? 25.448 59.91  35.538 1   17.102 ? 775  SER   A OG   1 
ATOM   4011 H H    . SER   A 1 266 ? 29.088 59.707 36.741 1   14.287 ? 775  SER   A H    1 
ATOM   4012 H HA   . SER   A 1 266 ? 27.057 61.443 37.018 1   13.565 ? 775  SER   A HA   1 
ATOM   4013 H HB2  . SER   A 1 266 ? 27.274 60.432 34.987 1   14.668 ? 775  SER   A HB2  1 
ATOM   4014 H HB3  . SER   A 1 266 ? 27.188 58.977 35.619 1   14.656 ? 775  SER   A HB3  1 
ATOM   4015 H HG   . SER   A 1 266 ? 25.245 59.598 34.777 0   30     ? 775  SER   A HG   1 
ATOM   4016 N N    . ILE   A 1 267 ? 26.632 58.655 38.564 1   10.823 ? 776  ILE   A N    1 
ATOM   4017 C CA   . ILE   A 1 267 ? 25.869 57.987 39.597 1   10.792 ? 776  ILE   A CA   1 
ATOM   4018 C C    . ILE   A 1 267 ? 26.017 58.71  40.934 1   10.514 ? 776  ILE   A C    1 
ATOM   4019 O O    . ILE   A 1 267 ? 25.042 58.796 41.676 1   9.913  ? 776  ILE   A O    1 
ATOM   4020 C CB   . ILE   A 1 267 ? 26.261 56.501 39.669 1   10.937 ? 776  ILE   A CB   1 
ATOM   4021 C CG1  . ILE   A 1 267 ? 25.7   55.764 38.47  1   10.826 ? 776  ILE   A CG1  1 
ATOM   4022 C CG2  . ILE   A 1 267 ? 25.815 55.834 40.978 1   11.153 ? 776  ILE   A CG2  1 
ATOM   4023 C CD1  . ILE   A 1 267 ? 26.344 54.432 38.243 1   11.09  ? 776  ILE   A CD1  1 
ATOM   4024 H H    . ILE   A 1 267 ? 27.344 58.219 38.191 1   11.171 ? 776  ILE   A H    1 
ATOM   4025 H HA   . ILE   A 1 267 ? 24.927 58.029 39.34  1   10.78  ? 776  ILE   A HA   1 
ATOM   4026 H HB   . ILE   A 1 267 ? 27.236 56.447 39.622 1   10.932 ? 776  ILE   A HB   1 
ATOM   4027 H HG12 . ILE   A 1 267 ? 24.738 55.633 38.601 1   10.912 ? 776  ILE   A HG12 1 
ATOM   4028 H HG13 . ILE   A 1 267 ? 25.823 56.316 37.671 1   10.911 ? 776  ILE   A HG13 1 
ATOM   4029 H HG21 . ILE   A 1 267 ? 25.867 54.869 40.888 1   11.086 ? 776  ILE   A HG21 1 
ATOM   4030 H HG22 . ILE   A 1 267 ? 24.899 56.089 41.178 1   11.085 ? 776  ILE   A HG22 1 
ATOM   4031 H HG23 . ILE   A 1 267 ? 26.395 56.12  41.704 1   11.085 ? 776  ILE   A HG23 1 
ATOM   4032 H HD11 . ILE   A 1 267 ? 27.314 54.521 38.305 1   11.008 ? 776  ILE   A HD11 1 
ATOM   4033 H HD12 . ILE   A 1 267 ? 26.107 54.105 37.354 1   11.008 ? 776  ILE   A HD12 1 
ATOM   4034 H HD13 . ILE   A 1 267 ? 26.034 53.795 38.913 1   11.002 ? 776  ILE   A HD13 1 
ATOM   4035 N N    . LEU   A 1 268 ? 27.235 59.186 41.25  1   9.863  ? 777  LEU   A N    1 
ATOM   4036 C CA   . LEU   A 1 268 ? 27.425 59.974 42.455 1   9.4    ? 777  LEU   A CA   1 
ATOM   4037 C C    . LEU   A 1 268 ? 26.475 61.172 42.447 1   9.84   ? 777  LEU   A C    1 
ATOM   4038 O O    . LEU   A 1 268 ? 25.759 61.413 43.415 1   11.27  ? 777  LEU   A O    1 
ATOM   4039 C CB   . LEU   A 1 268 ? 28.892 60.391 42.554 1   9.784  ? 777  LEU   A CB   1 
ATOM   4040 C CG   . LEU   A 1 268 ? 29.201 61.417 43.648 1   9.544  ? 777  LEU   A CG   1 
ATOM   4041 C CD1  . LEU   A 1 268 ? 28.873 60.8   44.982 1   9.771  ? 777  LEU   A CD1  1 
ATOM   4042 C CD2  . LEU   A 1 268 ? 30.646 61.855 43.518 1   10.547 ? 777  LEU   A CD2  1 
ATOM   4043 H H    . LEU   A 1 268 ? 27.952 59.009 40.712 1   9.916  ? 777  LEU   A H    1 
ATOM   4044 H HA   . LEU   A 1 268 ? 27.199 59.404 43.233 1   9.639  ? 777  LEU   A HA   1 
ATOM   4045 H HB2  . LEU   A 1 268 ? 29.432 59.585 42.719 1   9.682  ? 777  LEU   A HB2  1 
ATOM   4046 H HB3  . LEU   A 1 268 ? 29.164 60.768 41.686 1   9.672  ? 777  LEU   A HB3  1 
ATOM   4047 H HG   . LEU   A 1 268 ? 28.621 62.21  43.514 1   9.811  ? 777  LEU   A HG   1 
ATOM   4048 H HD11 . LEU   A 1 268 ? 27.908 60.768 45.098 1   9.702  ? 777  LEU   A HD11 1 
ATOM   4049 H HD12 . LEU   A 1 268 ? 29.265 61.336 45.692 1   9.703  ? 777  LEU   A HD12 1 
ATOM   4050 H HD13 . LEU   A 1 268 ? 29.233 59.898 45.022 1   9.703  ? 777  LEU   A HD13 1 
ATOM   4051 H HD21 . LEU   A 1 268 ? 30.787 62.256 42.644 1   10.24  ? 777  LEU   A HD21 1 
ATOM   4052 H HD22 . LEU   A 1 268 ? 31.229 61.084 43.618 1   10.24  ? 777  LEU   A HD22 1 
ATOM   4053 H HD23 . LEU   A 1 268 ? 30.851 62.507 44.21  1   10.24  ? 777  LEU   A HD23 1 
ATOM   4054 N N    . LYS   A 1 269 ? 26.466 61.94  41.358 1   10.691 ? 778  LYS   A N    1 
ATOM   4055 C CA   . LYS   A 1 269 ? 25.597 63.101 41.248 1   10.799 ? 778  LYS   A CA   1 
ATOM   4056 C C    . LYS   A 1 269 ? 24.13  62.753 41.509 1   10.341 ? 778  LYS   A C    1 
ATOM   4057 O O    . LYS   A 1 269 ? 23.444 63.438 42.282 1   9.155  ? 778  LYS   A O    1 
ATOM   4058 C CB   . LYS   A 1 269 ? 25.773 63.73  39.869 1   12.638 ? 778  LYS   A CB   1 
ATOM   4059 H H    . LYS   A 1 269 ? 27.022 61.736 40.662 1   10.507 ? 778  LYS   A H    1 
ATOM   4060 H HA   . LYS   A 1 269 ? 25.884 63.761 41.93  1   11.075 ? 778  LYS   A HA   1 
ATOM   4061 H HB2  . LYS   A 1 269 ? 26.708 63.847 39.671 0   30     ? 778  LYS   A HB2  1 
ATOM   4062 H HB3  . LYS   A 1 269 ? 24.858 63.925 39.506 0   30     ? 778  LYS   A HB3  1 
ATOM   4063 N N    . SER   A 1 270 ? 23.678 61.637 40.91  1   10.286 ? 779  SER   A N    1 
ATOM   4064 C CA   . SER   A 1 270 ? 22.315 61.155 41.08  1   9.877  ? 779  SER   A CA   1 
ATOM   4065 C C    . SER   A 1 270 ? 22.003 60.779 42.525 1   9.578  ? 779  SER   A C    1 
ATOM   4066 O O    . SER   A 1 270 ? 20.874 61.003 42.952 1   10.876 ? 779  SER   A O    1 
ATOM   4067 C CB   . SER   A 1 270 ? 22.026 60.005 40.139 1   10.521 ? 779  SER   A CB   1 
ATOM   4068 O OG   . SER   A 1 270 ? 21.968 60.478 38.797 1   11.284 ? 779  SER   A OG   1 
ATOM   4069 H H    . SER   A 1 270 ? 24.244 61.161 40.373 1   10.227 ? 779  SER   A H    1 
ATOM   4070 H HA   . SER   A 1 270 ? 21.71  61.899 40.833 1   10.065 ? 779  SER   A HA   1 
ATOM   4071 H HB2  . SER   A 1 270 ? 22.729 59.334 40.22  1   10.579 ? 779  SER   A HB2  1 
ATOM   4072 H HB3  . SER   A 1 270 ? 21.174 59.593 40.379 1   10.548 ? 779  SER   A HB3  1 
ATOM   4073 H HG   . SER   A 1 270 ? 21.809 59.807 38.289 0   30     ? 779  SER   A HG   1 
ATOM   4074 N N    . HIS   A 1 271 ? 22.949 60.166 43.268 1   9.236  ? 780  HIS   A N    1 
ATOM   4075 C CA   . HIS   A 1 271 ? 22.766 59.965 44.703 1   9.335  ? 780  HIS   A CA   1 
ATOM   4076 C C    . HIS   A 1 271 ? 22.737 61.303 45.461 1   9.576  ? 780  HIS   A C    1 
ATOM   4077 O O    . HIS   A 1 271 ? 22.056 61.433 46.476 1   10.144 ? 780  HIS   A O    1 
ATOM   4078 C CB   . HIS   A 1 271 ? 23.862 59.073 45.304 1   8.971  ? 780  HIS   A CB   1 
ATOM   4079 C CG   . HIS   A 1 271 ? 23.809 57.638 44.878 1   9.044  ? 780  HIS   A CG   1 
ATOM   4080 N ND1  . HIS   A 1 271 ? 22.733 56.83  45.152 1   8.855  ? 780  HIS   A ND1  1 
ATOM   4081 C CD2  . HIS   A 1 271 ? 24.736 56.838 44.32  1   9.252  ? 780  HIS   A CD2  1 
ATOM   4082 C CE1  . HIS   A 1 271 ? 23.002 55.592 44.756 1   9.73   ? 780  HIS   A CE1  1 
ATOM   4083 N NE2  . HIS   A 1 271 ? 24.2   55.568 44.23  1   9.168  ? 780  HIS   A NE2  1 
ATOM   4084 H H    . HIS   A 1 271 ? 23.716 59.867 42.871 1   9.342  ? 780  HIS   A H    1 
ATOM   4085 H HA   . HIS   A 1 271 ? 21.894 59.517 44.836 1   9.3    ? 780  HIS   A HA   1 
ATOM   4086 H HB2  . HIS   A 1 271 ? 24.736 59.444 45.054 1   9.07   ? 780  HIS   A HB2  1 
ATOM   4087 H HB3  . HIS   A 1 271 ? 23.797 59.115 46.281 1   9.072  ? 780  HIS   A HB3  1 
ATOM   4088 H HD1  . HIS   A 1 271 ? 21.987 57.102 45.526 0   30     ? 780  HIS   A HD1  1 
ATOM   4089 H HD2  . HIS   A 1 271 ? 25.588 57.093 44.026 1   9.2    ? 780  HIS   A HD2  1 
ATOM   4090 H HE1  . HIS   A 1 271 ? 22.407 54.864 44.798 1   9.384  ? 780  HIS   A HE1  1 
ATOM   4091 H HE2  . HIS   A 1 271 ? 24.589 54.866 43.871 0   30     ? 780  HIS   A HE2  1 
ATOM   4092 N N    . GLU   A 1 272 ? 23.546 62.262 45.038 1   9.615  ? 781  GLU   A N    1 
ATOM   4093 C CA   . GLU   A 1 272 ? 23.703 63.525 45.754 1   9.694  ? 781  GLU   A CA   1 
ATOM   4094 C C    . GLU   A 1 272 ? 22.476 64.443 45.602 1   10.478 ? 781  GLU   A C    1 
ATOM   4095 O O    . GLU   A 1 272 ? 22.162 65.194 46.512 1   11.537 ? 781  GLU   A O    1 
ATOM   4096 C CB   . GLU   A 1 272 ? 24.923 64.276 45.218 1   9.174  ? 781  GLU   A CB   1 
ATOM   4097 C CG   . GLU   A 1 272 ? 26.28  63.673 45.597 1   9.504  ? 781  GLU   A CG   1 
ATOM   4098 C CD   . GLU   A 1 272 ? 27.476 64.478 45.08  1   9.72   ? 781  GLU   A CD   1 
ATOM   4099 O OE1  . GLU   A 1 272 ? 27.253 65.28  44.142 1   9.434  ? 781  GLU   A OE1  1 
ATOM   4100 O OE2  . GLU   A 1 272 ? 28.618 64.293 45.569 1   9.957  ? 781  GLU   A OE2  1 
ATOM   4101 H H    . GLU   A 1 272 ? 24.032 62.129 44.275 1   9.617  ? 781  GLU   A H    1 
ATOM   4102 H HA   . GLU   A 1 272 ? 23.837 63.325 46.711 1   9.719  ? 781  GLU   A HA   1 
ATOM   4103 H HB2  . GLU   A 1 272 ? 24.861 64.314 44.242 1   9.367  ? 781  GLU   A HB2  1 
ATOM   4104 H HB3  . GLU   A 1 272 ? 24.895 65.196 45.553 1   9.371  ? 781  GLU   A HB3  1 
ATOM   4105 H HG2  . GLU   A 1 272 ? 26.343 63.615 46.573 1   9.479  ? 781  GLU   A HG2  1 
ATOM   4106 H HG3  . GLU   A 1 272 ? 26.338 62.763 45.243 1   9.488  ? 781  GLU   A HG3  1 
ATOM   4107 N N    . ASN   A 1 273 ? 21.799 64.415 44.443 1   11.581 ? 782  ASN   A N    1 
ATOM   4108 C CA   . ASN   A 1 273 ? 20.871 65.479 44.064 1   12.085 ? 782  ASN   A CA   1 
ATOM   4109 C C    . ASN   A 1 273 ? 19.407 65.036 44.051 1   13.233 ? 782  ASN   A C    1 
ATOM   4110 O O    . ASN   A 1 273 ? 18.552 65.779 43.548 1   15.061 ? 782  ASN   A O    1 
ATOM   4111 C CB   . ASN   A 1 273 ? 21.279 66.06  42.723 1   12.437 ? 782  ASN   A CB   1 
ATOM   4112 C CG   . ASN   A 1 273 ? 21.044 65.146 41.549 1   13.47  ? 782  ASN   A CG   1 
ATOM   4113 O OD1  . ASN   A 1 273 ? 20.521 64.034 41.688 1   15.02  ? 782  ASN   A OD1  1 
ATOM   4114 N ND2  . ASN   A 1 273 ? 21.4   65.62  40.371 1   13.808 ? 782  ASN   A ND2  1 
ATOM   4115 H H    . ASN   A 1 273 ? 21.917 63.712 43.872 1   11.422 ? 782  ASN   A H    1 
ATOM   4116 H HA   . ASN   A 1 273 ? 20.955 66.203 44.725 1   12.238 ? 782  ASN   A HA   1 
ATOM   4117 H HB2  . ASN   A 1 273 ? 20.784 66.89  42.577 1   12.597 ? 782  ASN   A HB2  1 
ATOM   4118 H HB3  . ASN   A 1 273 ? 22.23  66.286 42.757 1   12.588 ? 782  ASN   A HB3  1 
ATOM   4119 H HD21 . ASN   A 1 273 ? 21.283 65.128 39.643 1   13.711 ? 782  ASN   A HD21 1 
ATOM   4120 H HD22 . ASN   A 1 273 ? 21.756 66.431 40.306 1   13.696 ? 782  ASN   A HD22 1 
ATOM   4121 N N    . GLY   A 1 274 ? 19.135 63.855 44.587 1   12.133 ? 783  GLY   A N    1 
ATOM   4122 C CA   . GLY   A 1 274 ? 17.773 63.324 44.685 1   14.523 ? 783  GLY   A CA   1 
ATOM   4123 C C    . GLY   A 1 274 ? 17.277 62.582 43.429 1   13.206 ? 783  GLY   A C    1 
ATOM   4124 O O    . GLY   A 1 274 ? 16.147 62.109 43.434 1   13.714 ? 783  GLY   A O    1 
ATOM   4125 H H    . GLY   A 1 274 ? 19.821 63.348 44.914 1   12.869 ? 783  GLY   A H    1 
ATOM   4126 H HA2  . GLY   A 1 274 ? 17.73  62.712 45.456 1   13.654 ? 783  GLY   A HA2  1 
ATOM   4127 H HA3  . GLY   A 1 274 ? 17.16  64.072 44.872 1   13.699 ? 783  GLY   A HA3  1 
ATOM   4128 N N    . PHE   A 1 275 ? 18.095 62.436 42.363 1   13.258 ? 784  PHE   A N    1 
ATOM   4129 C CA   . PHE   A 1 275 ? 17.615 61.81  41.13  1   13.206 ? 784  PHE   A CA   1 
ATOM   4130 C C    . PHE   A 1 275 ? 17.256 60.334 41.362 1   12.204 ? 784  PHE   A C    1 
ATOM   4131 O O    . PHE   A 1 275 ? 16.196 59.85  40.908 1   12.6   ? 784  PHE   A O    1 
ATOM   4132 C CB   . PHE   A 1 275 ? 18.614 61.904 39.97  1   14.379 ? 784  PHE   A CB   1 
ATOM   4133 C CG   . PHE   A 1 275 ? 18.095 61.288 38.67  1   15.599 ? 784  PHE   A CG   1 
ATOM   4134 C CD1  . PHE   A 1 275 ? 17.074 61.904 37.952 1   18.623 ? 784  PHE   A CD1  1 
ATOM   4135 C CD2  . PHE   A 1 275 ? 18.64  60.126 38.151 1   16.327 ? 784  PHE   A CD2  1 
ATOM   4136 C CE1  . PHE   A 1 275 ? 16.601 61.349 36.767 1   17.103 ? 784  PHE   A CE1  1 
ATOM   4137 C CE2  . PHE   A 1 275 ? 18.172 59.586 36.95  1   16.913 ? 784  PHE   A CE2  1 
ATOM   4138 C CZ   . PHE   A 1 275 ? 17.157 60.204 36.264 1   16.299 ? 784  PHE   A CZ   1 
ATOM   4139 H H    . PHE   A 1 275 ? 18.961 62.725 42.407 1   13.233 ? 784  PHE   A H    1 
ATOM   4140 H HA   . PHE   A 1 275 ? 16.786 62.285 40.854 1   13.234 ? 784  PHE   A HA   1 
ATOM   4141 H HB2  . PHE   A 1 275 ? 18.824 62.851 39.813 1   14.365 ? 784  PHE   A HB2  1 
ATOM   4142 H HB3  . PHE   A 1 275 ? 19.443 61.446 40.232 1   14.355 ? 784  PHE   A HB3  1 
ATOM   4143 H HD1  . PHE   A 1 275 ? 16.684 62.697 38.285 1   17.482 ? 784  PHE   A HD1  1 
ATOM   4144 H HD2  . PHE   A 1 275 ? 19.343 59.697 38.613 1   16.279 ? 784  PHE   A HD2  1 
ATOM   4145 H HE1  . PHE   A 1 275 ? 15.906 61.779 36.294 1   17.222 ? 784  PHE   A HE1  1 
ATOM   4146 H HE2  . PHE   A 1 275 ? 18.551 58.789 36.614 1   16.631 ? 784  PHE   A HE2  1 
ATOM   4147 H HZ   . PHE   A 1 275 ? 16.833 59.832 35.459 1   16.631 ? 784  PHE   A HZ   1 
ATOM   4148 N N    . MET   A 1 276 ? 18.101 59.597 42.095 1   12.229 ? 785  MET   A N    1 
ATOM   4149 C CA   . MET   A 1 276 ? 17.785 58.212 42.442 1   12.864 ? 785  MET   A CA   1 
ATOM   4150 C C    . MET   A 1 276 ? 16.471 58.094 43.215 1   12.351 ? 785  MET   A C    1 
ATOM   4151 O O    . MET   A 1 276 ? 15.695 57.166 43.004 1   10.059 ? 785  MET   A O    1 
ATOM   4152 C CB   . MET   A 1 276 ? 18.867 57.538 43.31  1   15.257 ? 785  MET   A CB   1 
ATOM   4153 C CG   . MET   A 1 276 ? 20.186 57.318 42.621 1   16.12  ? 785  MET   A CG   1 
ATOM   4154 S SD   . MET   A 1 276 ? 20.043 56.627 40.958 1   15.842 ? 785  MET   A SD   1 
ATOM   4155 C CE   . MET   A 1 276 ? 21.813 56.371 40.758 1   17.428 ? 785  MET   A CE   1 
ATOM   4156 H H    . MET   A 1 276 ? 18.891 59.958 42.382 1   12.39  ? 785  MET   A H    1 
ATOM   4157 H HA   . MET   A 1 276 ? 17.684 57.705 41.597 1   13.047 ? 785  MET   A HA   1 
ATOM   4158 H HB2  . MET   A 1 276 ? 19.016 58.093 44.105 1   14.867 ? 785  MET   A HB2  1 
ATOM   4159 H HB3  . MET   A 1 276 ? 18.525 56.671 43.616 1   14.855 ? 785  MET   A HB3  1 
ATOM   4160 H HG2  . MET   A 1 276 ? 20.66  58.171 42.562 1   15.818 ? 785  MET   A HG2  1 
ATOM   4161 H HG3  . MET   A 1 276 ? 20.731 56.713 43.162 1   15.847 ? 785  MET   A HG3  1 
ATOM   4162 H HE1  . MET   A 1 276 ? 22.004 56.138 39.832 1   16.986 ? 785  MET   A HE1  1 
ATOM   4163 H HE2  . MET   A 1 276 ? 22.287 57.19  40.993 1   16.939 ? 785  MET   A HE2  1 
ATOM   4164 H HE3  . MET   A 1 276 ? 22.104 55.648 41.344 1   16.936 ? 785  MET   A HE3  1 
ATOM   4165 N N    . GLU   A 1 277 ? 16.243 58.978 44.19  1   13.291 ? 786  GLU   A N    1 
ATOM   4166 C CA   . GLU   A 1 277 ? 14.99  58.95  44.932 1   14.816 ? 786  GLU   A CA   1 
ATOM   4167 C C    . GLU   A 1 277 ? 13.798 59.293 44.035 1   13.362 ? 786  GLU   A C    1 
ATOM   4168 O O    . GLU   A 1 277 ? 12.724 58.726 44.222 1   13.23  ? 786  GLU   A O    1 
ATOM   4169 C CB   . GLU   A 1 277 ? 15.048 59.859 46.161 1   16.898 ? 786  GLU   A CB   1 
ATOM   4170 C CG   . GLU   A 1 277 ? 16.261 59.489 47.008 1   20.927 ? 786  GLU   A CG   1 
ATOM   4171 C CD   . GLU   A 1 277 ? 16.23  60.018 48.414 1   26.192 ? 786  GLU   A CD   1 
ATOM   4172 O OE1  . GLU   A 1 277 ? 15.761 61.169 48.562 1   29.06  ? 786  GLU   A OE1  1 
ATOM   4173 O OE2  . GLU   A 1 277 ? 16.696 59.297 49.335 1   28.93  ? 786  GLU   A OE2  1 
ATOM   4174 H H    . GLU   A 1 277 ? 16.868 59.615 44.386 1   13.481 ? 786  GLU   A H    1 
ATOM   4175 H HA   . GLU   A 1 277 ? 14.859 58.026 45.264 1   14.554 ? 786  GLU   A HA   1 
ATOM   4176 H HB2  . GLU   A 1 277 ? 15.107 60.793 45.87  1   17.213 ? 786  GLU   A HB2  1 
ATOM   4177 H HB3  . GLU   A 1 277 ? 14.224 59.754 46.681 1   17.213 ? 786  GLU   A HB3  1 
ATOM   4178 H HG2  . GLU   A 1 277 ? 16.336 58.511 47.047 1   20.929 ? 786  GLU   A HG2  1 
ATOM   4179 H HG3  . GLU   A 1 277 ? 17.07  59.828 46.572 1   20.852 ? 786  GLU   A HG3  1 
ATOM   4180 N N    . ASP   A 1 278 ? 13.958 60.226 43.084 1   13.29  ? 787  ASP   A N    1 
ATOM   4181 C CA   . ASP   A 1 278 ? 12.893 60.492 42.118 1   13.249 ? 787  ASP   A CA   1 
ATOM   4182 C C    . ASP   A 1 278 ? 12.553 59.22  41.326 1   12.368 ? 787  ASP   A C    1 
ATOM   4183 O O    . ASP   A 1 278 ? 11.367 58.905 41.101 1   12.15  ? 787  ASP   A O    1 
ATOM   4184 C CB   . ASP   A 1 278 ? 13.243 61.651 41.193 1   14.055 ? 787  ASP   A CB   1 
ATOM   4185 C CG   . ASP   A 1 278 ? 13.365 63.03  41.84  1   16.803 ? 787  ASP   A CG   1 
ATOM   4186 O OD1  . ASP   A 1 278 ? 12.839 63.225 42.953 1   17.679 ? 787  ASP   A OD1  1 
ATOM   4187 O OD2  . ASP   A 1 278 ? 14.048 63.879 41.246 1   20.701 ? 787  ASP   A OD2  1 
ATOM   4188 H H    . ASP   A 1 278 ? 14.734 60.706 43.037 1   13.312 ? 787  ASP   A H    1 
ATOM   4189 H HA   . ASP   A 1 278 ? 12.09  60.76  42.621 1   13.257 ? 787  ASP   A HA   1 
ATOM   4190 H HB2  . ASP   A 1 278 ? 14.094 61.449 40.753 1   14.435 ? 787  ASP   A HB2  1 
ATOM   4191 H HB3  . ASP   A 1 278 ? 12.555 61.707 40.497 1   14.434 ? 787  ASP   A HB3  1 
ATOM   4192 N N    . LEU   A 1 279 ? 13.589 58.47  40.908 1   10.951 ? 788  LEU   A N    1 
ATOM   4193 C CA   . LEU   A 1 279 ? 13.382 57.202 40.204 1   11.405 ? 788  LEU   A CA   1 
ATOM   4194 C C    . LEU   A 1 279 ? 12.624 56.201 41.082 1   10.621 ? 788  LEU   A C    1 
ATOM   4195 O O    . LEU   A 1 279 ? 11.69  55.522 40.645 1   9.753  ? 788  LEU   A O    1 
ATOM   4196 C CB   . LEU   A 1 279 ? 14.724 56.629 39.761 1   11.55  ? 788  LEU   A CB   1 
ATOM   4197 C CG   . LEU   A 1 279 ? 15.443 57.347 38.623 1   12.393 ? 788  LEU   A CG   1 
ATOM   4198 C CD1  . LEU   A 1 279 ? 16.625 56.495 38.183 1   13.95  ? 788  LEU   A CD1  1 
ATOM   4199 C CD2  . LEU   A 1 279 ? 14.458 57.578 37.476 1   13.568 ? 788  LEU   A CD2  1 
ATOM   4200 H H    . LEU   A 1 279 ? 14.443 58.757 41.059 1   11.404 ? 788  LEU   A H    1 
ATOM   4201 H HA   . LEU   A 1 279 ? 12.827 57.385 39.405 1   11.234 ? 788  LEU   A HA   1 
ATOM   4202 H HB2  . LEU   A 1 279 ? 15.323 56.613 40.542 1   11.688 ? 788  LEU   A HB2  1 
ATOM   4203 H HB3  . LEU   A 1 279 ? 14.578 55.695 39.489 1   11.684 ? 788  LEU   A HB3  1 
ATOM   4204 H HG   . LEU   A 1 279 ? 15.774 58.222 38.951 1   12.713 ? 788  LEU   A HG   1 
ATOM   4205 H HD11 . LEU   A 1 279 ? 17.214 56.34  38.941 1   13.472 ? 788  LEU   A HD11 1 
ATOM   4206 H HD12 . LEU   A 1 279 ? 17.115 56.956 37.482 1   13.483 ? 788  LEU   A HD12 1 
ATOM   4207 H HD13 . LEU   A 1 279 ? 16.303 55.642 37.845 1   13.462 ? 788  LEU   A HD13 1 
ATOM   4208 H HD21 . LEU   A 1 279 ? 13.93  58.374 37.655 1   13.177 ? 788  LEU   A HD21 1 
ATOM   4209 H HD22 . LEU   A 1 279 ? 13.868 56.81  37.393 1   13.169 ? 788  LEU   A HD22 1 
ATOM   4210 H HD23 . LEU   A 1 279 ? 14.95  57.698 36.647 1   13.187 ? 788  LEU   A HD23 1 
ATOM   4211 N N    . ASP   A 1 280 ? 13.006 56.129 42.364 1   10.104 ? 789  ASP   A N    1 
ATOM   4212 C CA   . ASP   A 1 280 ? 12.309 55.305 43.345 1   10.317 ? 789  ASP   A CA   1 
ATOM   4213 C C    . ASP   A 1 280 ? 10.815 55.657 43.43  1   10.972 ? 789  ASP   A C    1 
ATOM   4214 O O    . ASP   A 1 280 ? 9.942  54.781 43.521 1   10.227 ? 789  ASP   A O    1 
ATOM   4215 C CB   . ASP   A 1 280 ? 12.988 55.438 44.696 1   11.048 ? 789  ASP   A CB   1 
ATOM   4216 C CG   . ASP   A 1 280 ? 14.289 54.677 44.882 1   12.273 ? 789  ASP   A CG   1 
ATOM   4217 O OD1  . ASP   A 1 280 ? 14.588 53.788 44.065 1   12.507 ? 789  ASP   A OD1  1 
ATOM   4218 O OD2  . ASP   A 1 280 ? 14.973 54.936 45.908 1   15.885 ? 789  ASP   A OD2  1 
ATOM   4219 H H    . ASP   A 1 280 ? 13.736 56.607 42.635 1   10.297 ? 789  ASP   A H    1 
ATOM   4220 H HA   . ASP   A 1 280 ? 12.385 54.366 43.063 1   10.543 ? 789  ASP   A HA   1 
ATOM   4221 H HB2  . ASP   A 1 280 ? 13.169 56.384 44.868 1   11.169 ? 789  ASP   A HB2  1 
ATOM   4222 H HB3  . ASP   A 1 280 ? 12.365 55.128 45.386 1   11.148 ? 789  ASP   A HB3  1 
ATOM   4223 N N    . LYS   A 1 281 ? 10.518 56.96  43.416 1   10.947 ? 790  LYS   A N    1 
ATOM   4224 C CA   . LYS   A 1 281 ? 9.159  57.451 43.576 1   12.055 ? 790  LYS   A CA   1 
ATOM   4225 C C    . LYS   A 1 281 ? 8.373  57.23  42.287 1   11.622 ? 790  LYS   A C    1 
ATOM   4226 O O    . LYS   A 1 281 ? 7.163  57.272 42.308 1   12.434 ? 790  LYS   A O    1 
ATOM   4227 C CB   . LYS   A 1 281 ? 9.18   58.927 44.002 1   13.942 ? 790  LYS   A CB   1 
ATOM   4228 C CG   . LYS   A 1 281 ? 9.652  59.09  45.477 1   15.489 ? 790  LYS   A CG   1 
ATOM   4229 C CD   . LYS   A 1 281 ? 9.817  60.538 45.957 1   16.584 ? 790  LYS   A CD   1 
ATOM   4230 C CE   . LYS   A 1 281 ? 10.503 60.633 47.333 1   16.047 ? 790  LYS   A CE   1 
ATOM   4231 H H    . LYS   A 1 281 ? 11.191 57.569 43.308 1   11.221 ? 790  LYS   A H    1 
ATOM   4232 H HA   . LYS   A 1 281 ? 8.725  56.93  44.299 1   12.051 ? 790  LYS   A HA   1 
ATOM   4233 H HB2  . LYS   A 1 281 ? 9.784  59.429 43.415 1   13.789 ? 790  LYS   A HB2  1 
ATOM   4234 H HB3  . LYS   A 1 281 ? 8.279  59.305 43.911 1   13.794 ? 790  LYS   A HB3  1 
ATOM   4235 H HG2  . LYS   A 1 281 ? 9.002  58.639 46.059 1   15.361 ? 790  LYS   A HG2  1 
ATOM   4236 H HG3  . LYS   A 1 281 ? 10.51  58.624 45.579 1   15.33  ? 790  LYS   A HG3  1 
ATOM   4237 H HD2  . LYS   A 1 281 ? 10.35  61.034 45.298 1   16.208 ? 790  LYS   A HD2  1 
ATOM   4238 H HD3  . LYS   A 1 281 ? 8.931  60.96  46.011 1   16.208 ? 790  LYS   A HD3  1 
ATOM   4239 H HE2  . LYS   A 1 281 ? 11.467 60.628 47.193 0   30     ? 790  LYS   A HE2  1 
ATOM   4240 H HE3  . LYS   A 1 281 ? 9.826  60.684 48.016 0   30     ? 790  LYS   A HE3  1 
ATOM   4241 N N    . THR   A 1 282 ? 9.072  57.066 41.161 1   10.832 ? 791  THR   A N    1 
ATOM   4242 C CA   . THR   A 1 282 ? 8.468  56.747 39.868 1   10.274 ? 791  THR   A CA   1 
ATOM   4243 C C    . THR   A 1 282 ? 8.249  55.244 39.678 1   9.812  ? 791  THR   A C    1 
ATOM   4244 O O    . THR   A 1 282 ? 7.191  54.837 39.191 1   9.326  ? 791  THR   A O    1 
ATOM   4245 C CB   . THR   A 1 282 ? 9.359  57.306 38.759 1   10.395 ? 791  THR   A CB   1 
ATOM   4246 O OG1  . THR   A 1 282 ? 9.506  58.707 38.995 1   10.973 ? 791  THR   A OG1  1 
ATOM   4247 C CG2  . THR   A 1 282 ? 8.724  57.116 37.393 1   10.752 ? 791  THR   A CG2  1 
ATOM   4248 H H    . THR   A 1 282 ? 9.978  57.177 41.192 1   10.888 ? 791  THR   A H    1 
ATOM   4249 H HA   . THR   A 1 282 ? 7.597  57.197 39.818 1   10.409 ? 791  THR   A HA   1 
ATOM   4250 H HB   . THR   A 1 282 ? 10.244 56.87  38.781 1   10.544 ? 791  THR   A HB   1 
ATOM   4251 H HG1  . THR   A 1 282 ? 8.726  59.093 38.986 0   30     ? 791  THR   A HG1  1 
ATOM   4252 H HG21 . THR   A 1 282 ? 9.127  57.735 36.76  1   10.644 ? 791  THR   A HG21 1 
ATOM   4253 H HG22 . THR   A 1 282 ? 7.77   57.29  37.451 1   10.641 ? 791  THR   A HG22 1 
ATOM   4254 H HG23 . THR   A 1 282 ? 8.87   56.205 37.09  1   10.643 ? 791  THR   A HG23 1 
ATOM   4255 N N    . TRP   A 1 283 ? 9.226  54.414 40.065 1   9.073  ? 792  TRP   A N    1 
ATOM   4256 C CA   . TRP   A 1 283 ? 9.248  53.017 39.663 1   9.303  ? 792  TRP   A CA   1 
ATOM   4257 C C    . TRP   A 1 283 ? 9.125  52.016 40.806 1   9.677  ? 792  TRP   A C    1 
ATOM   4258 O O    . TRP   A 1 283 ? 8.871  50.852 40.505 1   9.31   ? 792  TRP   A O    1 
ATOM   4259 C CB   . TRP   A 1 283 ? 10.559 52.724 38.936 1   9.726  ? 792  TRP   A CB   1 
ATOM   4260 C CG   . TRP   A 1 283 ? 10.692 53.493 37.664 1   10.012 ? 792  TRP   A CG   1 
ATOM   4261 C CD1  . TRP   A 1 283 ? 11.52  54.548 37.424 1   10.645 ? 792  TRP   A CD1  1 
ATOM   4262 C CD2  . TRP   A 1 283 ? 9.921  53.292 36.473 1   10.451 ? 792  TRP   A CD2  1 
ATOM   4263 N NE1  . TRP   A 1 283 ? 11.337 55.011 36.152 1   10.877 ? 792  TRP   A NE1  1 
ATOM   4264 C CE2  . TRP   A 1 283 ? 10.363 54.255 35.542 1   11.4   ? 792  TRP   A CE2  1 
ATOM   4265 C CE3  . TRP   A 1 283 ? 8.922  52.393 36.105 1   11.155 ? 792  TRP   A CE3  1 
ATOM   4266 C CZ2  . TRP   A 1 283 ? 9.826  54.326 34.261 1   11.485 ? 792  TRP   A CZ2  1 
ATOM   4267 C CZ3  . TRP   A 1 283 ? 8.394  52.467 34.832 1   11.356 ? 792  TRP   A CZ3  1 
ATOM   4268 C CH2  . TRP   A 1 283 ? 8.827  53.43  33.938 1   11.029 ? 792  TRP   A CH2  1 
ATOM   4269 H H    . TRP   A 1 283 ? 9.906  54.733 40.585 1   9.315  ? 792  TRP   A H    1 
ATOM   4270 H HA   . TRP   A 1 283 ? 8.5    52.859 39.026 1   9.403  ? 792  TRP   A HA   1 
ATOM   4271 H HB2  . TRP   A 1 283 ? 11.306 52.954 39.529 1   9.693  ? 792  TRP   A HB2  1 
ATOM   4272 H HB3  . TRP   A 1 283 ? 10.602 51.765 38.734 1   9.692  ? 792  TRP   A HB3  1 
ATOM   4273 H HD1  . TRP   A 1 283 ? 12.14  54.906 38.038 1   10.549 ? 792  TRP   A HD1  1 
ATOM   4274 H HE1  . TRP   A 1 283 ? 11.775 55.671 35.787 1   10.936 ? 792  TRP   A HE1  1 
ATOM   4275 H HE3  . TRP   A 1 283 ? 8.622  51.739 36.712 1   11.015 ? 792  TRP   A HE3  1 
ATOM   4276 H HZ2  . TRP   A 1 283 ? 10.116 54.979 33.647 1   11.346 ? 792  TRP   A HZ2  1 
ATOM   4277 H HZ3  . TRP   A 1 283 ? 7.714  51.867 34.575 1   11.226 ? 792  TRP   A HZ3  1 
ATOM   4278 H HH2  . TRP   A 1 283 ? 8.45   53.458 33.077 1   11.213 ? 792  TRP   A HH2  1 
ATOM   4279 N N    . VAL   A 1 284 ? 9.424  52.41  42.063 1   9.37   ? 793  VAL   A N    1 
ATOM   4280 C CA   . VAL   A 1 284 ? 9.577  51.45  43.154 1   10.479 ? 793  VAL   A CA   1 
ATOM   4281 C C    . VAL   A 1 284 ? 8.481  51.575 44.222 1   10.562 ? 793  VAL   A C    1 
ATOM   4282 O O    . VAL   A 1 284 ? 7.873  50.564 44.612 1   10.392 ? 793  VAL   A O    1 
ATOM   4283 C CB   . VAL   A 1 284 ? 11.007 51.624 43.725 1   12.047 ? 793  VAL   A CB   1 
ATOM   4284 C CG1  . VAL   A 1 284 ? 11.253 50.828 44.989 1   12.728 ? 793  VAL   A CG1  1 
ATOM   4285 C CG2  . VAL   A 1 284 ? 12.054 51.285 42.662 1   12.375 ? 793  VAL   A CG2  1 
ATOM   4286 H H    . VAL   A 1 284 ? 9.538  53.298 42.242 1   9.687  ? 793  VAL   A H    1 
ATOM   4287 H HA   . VAL   A 1 284 ? 9.518  50.553 42.774 1   10.519 ? 793  VAL   A HA   1 
ATOM   4288 H HB   . VAL   A 1 284 ? 11.113 52.576 43.951 1   11.904 ? 793  VAL   A HB   1 
ATOM   4289 H HG11 . VAL   A 1 284 ? 10.879 49.938 44.889 1   12.528 ? 793  VAL   A HG11 1 
ATOM   4290 H HG12 . VAL   A 1 284 ? 10.832 51.275 45.741 1   12.52  ? 793  VAL   A HG12 1 
ATOM   4291 H HG13 . VAL   A 1 284 ? 12.21  50.76  45.15  1   12.52  ? 793  VAL   A HG13 1 
ATOM   4292 H HG21 . VAL   A 1 284 ? 12.94  51.303 43.061 1   12.275 ? 793  VAL   A HG21 1 
ATOM   4293 H HG22 . VAL   A 1 284 ? 12.012 51.938 41.943 1   12.259 ? 793  VAL   A HG22 1 
ATOM   4294 H HG23 . VAL   A 1 284 ? 11.879 50.398 42.305 1   12.273 ? 793  VAL   A HG23 1 
ATOM   4295 N N    . ARG   A 1 285 ? 8.143  52.804 44.619 1   10.274 ? 794  ARG   A N    1 
ATOM   4296 C CA   . ARG   A 1 285 ? 7.14   53.027 45.66  1   10.633 ? 794  ARG   A CA   1 
ATOM   4297 C C    . ARG   A 1 285 ? 6.219  54.185 45.287 1   10.238 ? 794  ARG   A C    1 
ATOM   4298 O O    . ARG   A 1 285 ? 6.605  55.333 45.396 1   9.626  ? 794  ARG   A O    1 
ATOM   4299 C CB   . ARG   A 1 285 ? 7.849  53.382 46.968 1   10.664 ? 794  ARG   A CB   1 
ATOM   4300 C CG   . ARG   A 1 285 ? 8.423  52.17  47.697 1   11.346 ? 794  ARG   A CG   1 
ATOM   4301 C CD   . ARG   A 1 285 ? 9.058  52.565 49.018 1   12.245 ? 794  ARG   A CD   1 
ATOM   4302 N NE   . ARG   A 1 285 ? 10.355 53.214 48.798 1   14.184 ? 794  ARG   A NE   1 
ATOM   4303 C CZ   . ARG   A 1 285 ? 11.491 52.556 48.536 1   15.084 ? 794  ARG   A CZ   1 
ATOM   4304 N NH1  . ARG   A 1 285 ? 12.553 53.227 48.185 1   20.717 ? 794  ARG   A NH1  1 
ATOM   4305 N NH2  . ARG   A 1 285 ? 11.573 51.249 48.59  1   15.145 ? 794  ARG   A NH2  1 
ATOM   4306 H H    . ARG   A 1 285 ? 8.55   53.528 44.239 1   10.408 ? 794  ARG   A H    1 
ATOM   4307 H HA   . ARG   A 1 285 ? 6.603  52.204 45.778 1   10.502 ? 794  ARG   A HA   1 
ATOM   4308 H HB2  . ARG   A 1 285 ? 8.578  54.009 46.774 1   10.808 ? 794  ARG   A HB2  1 
ATOM   4309 H HB3  . ARG   A 1 285 ? 7.214  53.836 47.562 1   10.809 ? 794  ARG   A HB3  1 
ATOM   4310 H HG2  . ARG   A 1 285 ? 7.705  51.522 47.867 1   11.393 ? 794  ARG   A HG2  1 
ATOM   4311 H HG3  . ARG   A 1 285 ? 9.098  51.738 47.131 1   11.427 ? 794  ARG   A HG3  1 
ATOM   4312 H HD2  . ARG   A 1 285 ? 8.465  53.183 49.491 1   12.456 ? 794  ARG   A HD2  1 
ATOM   4313 H HD3  . ARG   A 1 285 ? 9.18   51.771 49.577 1   12.49  ? 794  ARG   A HD3  1 
ATOM   4314 H HE   . ARG   A 1 285 ? 10.391 54.083 48.843 1   13.986 ? 794  ARG   A HE   1 
ATOM   4315 H HH11 . ARG   A 1 285 ? 12.471 53.943 47.673 1   18.731 ? 794  ARG   A HH11 1 
ATOM   4316 H HH12 . ARG   A 1 285 ? 13.351 52.962 48.461 1   18.742 ? 794  ARG   A HH12 1 
ATOM   4317 H HH21 . ARG   A 1 285 ? 11.079 50.754 48.049 1   15.053 ? 794  ARG   A HH21 1 
ATOM   4318 H HH22 . ARG   A 1 285 ? 12.121 50.867 49.169 1   15.109 ? 794  ARG   A HH22 1 
ATOM   4319 N N    . TYR   A 1 286 ? 5.013  53.874 44.842 1   11.157 ? 795  TYR   A N    1 
ATOM   4320 C CA   . TYR   A 1 286 ? 4.119  54.913 44.35  1   11.495 ? 795  TYR   A CA   1 
ATOM   4321 C C    . TYR   A 1 286 ? 2.637  54.595 44.536 1   11.066 ? 795  TYR   A C    1 
ATOM   4322 O O    . TYR   A 1 286 ? 1.832  55.524 44.429 1   10.062 ? 795  TYR   A O    1 
ATOM   4323 C CB   . TYR   A 1 286 ? 4.389  55.201 42.867 1   12.317 ? 795  TYR   A CB   1 
ATOM   4324 C CG   . TYR   A 1 286 ? 4.447  53.996 41.937 1   12.269 ? 795  TYR   A CG   1 
ATOM   4325 C CD1  . TYR   A 1 286 ? 5.585  53.195 41.853 1   13.366 ? 795  TYR   A CD1  1 
ATOM   4326 C CD2  . TYR   A 1 286 ? 3.351  53.653 41.167 1   13.307 ? 795  TYR   A CD2  1 
ATOM   4327 C CE1  . TYR   A 1 286 ? 5.661  52.139 40.958 1   13.113 ? 795  TYR   A CE1  1 
ATOM   4328 C CE2  . TYR   A 1 286 ? 3.389  52.584 40.294 1   12.898 ? 795  TYR   A CE2  1 
ATOM   4329 C CZ   . TYR   A 1 286 ? 4.55   51.834 40.189 1   13.745 ? 795  TYR   A CZ   1 
ATOM   4330 O OH   . TYR   A 1 286 ? 4.583  50.783 39.347 1   13.06  ? 795  TYR   A OH   1 
ATOM   4331 H H    . TYR   A 1 286 ? 4.745  53.001 44.824 1   11.001 ? 795  TYR   A H    1 
ATOM   4332 H HA   . TYR   A 1 286 ? 4.312  55.745 44.859 1   11.523 ? 795  TYR   A HA   1 
ATOM   4333 H HB2  . TYR   A 1 286 ? 3.692  55.812 42.542 1   12.109 ? 795  TYR   A HB2  1 
ATOM   4334 H HB3  . TYR   A 1 286 ? 5.243  55.681 42.803 1   12.115 ? 795  TYR   A HB3  1 
ATOM   4335 H HD1  . TYR   A 1 286 ? 6.349  53.427 42.355 1   13.047 ? 795  TYR   A HD1  1 
ATOM   4336 H HD2  . TYR   A 1 286 ? 2.569  54.18  41.215 1   12.96  ? 795  TYR   A HD2  1 
ATOM   4337 H HE1  . TYR   A 1 286 ? 6.437  51.611 40.904 1   13.248 ? 795  TYR   A HE1  1 
ATOM   4338 H HE2  . TYR   A 1 286 ? 2.64   52.375 39.763 1   13.176 ? 795  TYR   A HE2  1 
ATOM   4339 H HH   . TYR   A 1 286 ? 5.35   50.402 39.404 0   30     ? 795  TYR   A HH   1 
ATOM   4340 N N    . GLN   A 1 287 ? 2.242  53.327 44.773 1   11.151 ? 796  GLN   A N    1 
ATOM   4341 C CA   . GLN   A 1 287 ? 0.822  53.004 44.939 1   11.807 ? 796  GLN   A CA   1 
ATOM   4342 C C    . GLN   A 1 287 ? 0.647  51.673 45.673 1   11.608 ? 796  GLN   A C    1 
ATOM   4343 O O    . GLN   A 1 287 ? 1.618  50.94  45.847 1   11.455 ? 796  GLN   A O    1 
ATOM   4344 C CB   . GLN   A 1 287 ? 0.065  52.946 43.612 1   12.717 ? 796  GLN   A CB   1 
ATOM   4345 C CG   . GLN   A 1 287 ? 0.575  51.878 42.656 1   12.83  ? 796  GLN   A CG   1 
ATOM   4346 C CD   . GLN   A 1 287 ? -0.041 51.967 41.277 1   15.724 ? 796  GLN   A CD   1 
ATOM   4347 O OE1  . GLN   A 1 287 ? -0.266 53.055 40.72  1   16.814 ? 796  GLN   A OE1  1 
ATOM   4348 N NE2  . GLN   A 1 287 ? -0.228 50.801 40.688 1   17.754 ? 796  GLN   A NE2  1 
ATOM   4349 H H    . GLN   A 1 287 ? 2.858  52.654 44.823 1   11.272 ? 796  GLN   A H    1 
ATOM   4350 H HA   . GLN   A 1 287 ? 0.41   53.714 45.494 1   11.786 ? 796  GLN   A HA   1 
ATOM   4351 H HB2  . GLN   A 1 287 ? -0.883 52.78  43.796 1   12.557 ? 796  GLN   A HB2  1 
ATOM   4352 H HB3  . GLN   A 1 287 ? 0.133  53.82  43.176 1   12.54  ? 796  GLN   A HB3  1 
ATOM   4353 H HG2  . GLN   A 1 287 ? 1.549  51.959 42.572 1   13.412 ? 796  GLN   A HG2  1 
ATOM   4354 H HG3  . GLN   A 1 287 ? 0.382  50.991 43.028 1   13.451 ? 796  GLN   A HG3  1 
ATOM   4355 H HE21 . GLN   A 1 287 ? -0.956 50.664 40.2   1   17.087 ? 796  GLN   A HE21 1 
ATOM   4356 H HE22 . GLN   A 1 287 ? 0.375  50.156 40.78  1   17.036 ? 796  GLN   A HE22 1 
ATOM   4357 N N    . GLU   A 1 288 ? -0.594 51.356 46.066 1   10.665 ? 797  GLU   A N    1 
ATOM   4358 C CA   . GLU   A 1 288 ? -0.89  50.119 46.787 1   11.51  ? 797  GLU   A CA   1 
ATOM   4359 C C    . GLU   A 1 288 ? -0.957 48.924 45.823 1   12.462 ? 797  GLU   A C    1 
ATOM   4360 O O    . GLU   A 1 288 ? -0.925 49.1   44.597 1   14.049 ? 797  GLU   A O    1 
ATOM   4361 C CB   . GLU   A 1 288 ? -2.168 50.287 47.614 1   11.217 ? 797  GLU   A CB   1 
ATOM   4362 C CG   . GLU   A 1 288 ? -2.086 51.443 48.609 1   11.658 ? 797  GLU   A CG   1 
ATOM   4363 C CD   . GLU   A 1 288 ? -1.008 51.317 49.666 1   12.033 ? 797  GLU   A CD   1 
ATOM   4364 O OE1  . GLU   A 1 288 ? -0.476 50.187 49.862 1   12.828 ? 797  GLU   A OE1  1 
ATOM   4365 O OE2  . GLU   A 1 288 ? -0.639 52.372 50.233 1   11.066 ? 797  GLU   A OE2  1 
ATOM   4366 H H    . GLU   A 1 288 ? -1.281 51.93  45.881 1   11.103 ? 797  GLU   A H    1 
ATOM   4367 H HA   . GLU   A 1 288 ? -0.146 49.952 47.417 1   11.447 ? 797  GLU   A HA   1 
ATOM   4368 H HB2  . GLU   A 1 288 ? -2.921 50.439 47.006 1   11.386 ? 797  GLU   A HB2  1 
ATOM   4369 H HB3  . GLU   A 1 288 ? -2.341 49.455 48.102 1   11.405 ? 797  GLU   A HB3  1 
ATOM   4370 H HG2  . GLU   A 1 288 ? -1.935 52.276 48.114 1   11.632 ? 797  GLU   A HG2  1 
ATOM   4371 H HG3  . GLU   A 1 288 ? -2.951 51.529 49.062 1   11.639 ? 797  GLU   A HG3  1 
ATOM   4372 N N    . CYS   A 1 289 ? -0.983 47.706 46.378 1   13.783 ? 798  CYS   A N    1 
ATOM   4373 C CA   . CYS   A 1 289 ? -0.95  46.485 45.575 1   16.258 ? 798  CYS   A CA   1 
ATOM   4374 C C    . CYS   A 1 289 ? -2.194 46.394 44.678 1   18.873 ? 798  CYS   A C    1 
ATOM   4375 O O    . CYS   A 1 289 ? -3.295 46.722 45.1   1   17.913 ? 798  CYS   A O    1 
ATOM   4376 C CB   . CYS   A 1 289 ? -0.793 45.248 46.456 1   18.273 ? 798  CYS   A CB   1 
ATOM   4377 S SG   . CYS   A 1 289 ? -2.123 44.977 47.658 1   20.307 ? 798  CYS   A SG   1 
ATOM   4378 H H    . CYS   A 1 289 ? -1.022 47.633 47.288 1   13.95  ? 798  CYS   A H    1 
ATOM   4379 H HA   . CYS   A 1 289 ? -0.152 46.535 44.989 1   16.55  ? 798  CYS   A HA   1 
ATOM   4380 H HB2  . CYS   A 1 289 ? -0.736 44.454 45.879 1   18.136 ? 798  CYS   A HB2  1 
ATOM   4381 H HB3  . CYS   A 1 289 ? 0.053  45.317 46.95  1   18.061 ? 798  CYS   A HB3  1 
ATOM   4382 N N    . ASP   A 1 290 ? -2.033 46.006 43.41  1   21.426 ? 799  ASP   A N    1 
ATOM   4383 C CA   . ASP   A 1 290 ? -3.183 45.851 42.522 1   30.095 ? 799  ASP   A CA   1 
ATOM   4384 C C    . ASP   A 1 290 ? -2.954 44.682 41.554 1   35.021 ? 799  ASP   A C    1 
ATOM   4385 O O    . ASP   A 1 290 ? -3.618 44.642 40.517 1   33.541 ? 799  ASP   A O    1 
ATOM   4386 C CB   . ASP   A 1 290 ? -3.54  47.168 41.832 1   29.776 ? 799  ASP   A CB   1 
ATOM   4387 C CG   . ASP   A 1 290 ? -2.564 47.616 40.761 1   40.339 ? 799  ASP   A CG   1 
ATOM   4388 O OD1  . ASP   A 1 290 ? -2.869 48.636 40.076 1   44.854 ? 799  ASP   A OD1  1 
ATOM   4389 O OD2  . ASP   A 1 290 ? -1.51  46.927 40.636 1   38.932 ? 799  ASP   A OD2  1 
ATOM   4390 H H    . ASP   A 1 290 ? -1.192 45.859 43.083 1   22.606 ? 799  ASP   A H    1 
ATOM   4391 H HA   . ASP   A 1 290 ? -3.962 45.622 43.077 1   28.743 ? 799  ASP   A HA   1 
ATOM   4392 H HB2  . ASP   A 1 290 ? -4.424 47.077 41.42  1   32.03  ? 799  ASP   A HB2  1 
ATOM   4393 H HB3  . ASP   A 1 290 ? -3.594 47.872 42.51  1   32.008 ? 799  ASP   A HB3  1 
ATOM   4394 N N    . SER   A 1 291 ? -2.049 43.751 41.938 1   39.961 ? 800  SER   A N    1 
ATOM   4395 C CA   . SER   A 1 291 ? -1.411 42.7   41.135 1   45.021 ? 800  SER   A CA   1 
ATOM   4396 C C    . SER   A 1 291 ? -1.065 43.161 39.709 1   48.697 ? 800  SER   A C    1 
ATOM   4397 O O    . SER   A 1 291 ? -0.012 42.683 39.213 1   47.396 ? 800  SER   A O    1 
ATOM   4398 C CB   . SER   A 1 291 ? -2.205 41.435 41.154 1   44.26  ? 800  SER   A CB   1 
ATOM   4399 O OG   . SER   A 1 291 ? -2.542 41.133 42.499 1   49.598 ? 800  SER   A OG   1 
ATOM   4400 H H    . SER   A 1 291 ? -1.821 43.767 42.823 1   39.312 ? 800  SER   A H    1 
ATOM   4401 H HA   . SER   A 1 291 ? -0.549 42.498 41.579 1   43.775 ? 800  SER   A HA   1 
ATOM   4402 H HB2  . SER   A 1 291 ? -3.02  41.552 40.63  1   45.547 ? 800  SER   A HB2  1 
ATOM   4403 H HB3  . SER   A 1 291 ? -1.684 40.71  40.766 1   45.114 ? 800  SER   A HB3  1 
ATOM   4404 H HG   . SER   A 1 291 ? -3.138 40.425 42.661 0   30     ? 800  SER   A HG   1 
HETATM 4405 C C1   . A1ILR B 2 .   ? 22.413 38.13  42.806 1   11.014 ? 901  A1ILR A C1   1 
HETATM 4406 C C2   . A1ILR B 2 .   ? 22.842 38.451 44.145 1   12.719 ? 901  A1ILR A C2   1 
HETATM 4407 C C3   . A1ILR B 2 .   ? 22.501 39.443 45.06  1   13.951 ? 901  A1ILR A C3   1 
HETATM 4408 C C4   . A1ILR B 2 .   ? 23.302 39.366 46.22  1   14.259 ? 901  A1ILR A C4   1 
HETATM 4409 C C8   . A1ILR B 2 .   ? 20.803 38.437 41.025 1   10.189 ? 901  A1ILR A C8   1 
HETATM 4410 C C9   . A1ILR B 2 .   ? 21.197 39.45  39.953 1   10.316 ? 901  A1ILR A C9   1 
HETATM 4411 O O13  . A1ILR B 2 .   ? 22.742 37.998 38.931 1   9.586  ? 901  A1ILR A O13  1 
HETATM 4412 C C5   . A1ILR B 2 .   ? 24.223 38.331 46.27  1   14.439 ? 901  A1ILR A C5   1 
HETATM 4413 S S6   . A1ILR B 2 .   ? 24.101 37.482 44.801 1   15.244 ? 901  A1ILR A S6   1 
HETATM 4414 N N7   . A1ILR B 2 .   ? 21.315 38.74  42.33  1   10.021 ? 901  A1ILR A N7   1 
HETATM 4415 N N10  . A1ILR B 2 .   ? 21.08  40.864 40.458 1   9.728  ? 901  A1ILR A N10  1 
HETATM 4416 C C11  . A1ILR B 2 .   ? 22.512 39.164 39.292 1   10.327 ? 901  A1ILR A C11  1 
HETATM 4417 O O12  . A1ILR B 2 .   ? 23.27  40.171 39.091 1   10.646 ? 901  A1ILR A O12  1 
HETATM 4418 O O14  . A1ILR B 2 .   ? 23.074 37.307 42.186 1   10.919 ? 901  A1ILR A O14  1 
HETATM 4419 H H3   . A1ILR B 2 .   ? 21.755 40.207 44.891 1   13.667 ? 901  A1ILR A H3   1 
HETATM 4420 H H4   . A1ILR B 2 .   ? 23.158 40.042 47.053 1   14.199 ? 901  A1ILR A H4   1 
HETATM 4421 H H81  . A1ILR B 2 .   ? 21.101 37.434 40.726 1   10.221 ? 901  A1ILR A H81  1 
HETATM 4422 H H8   . A1ILR B 2 .   ? 19.715 38.438 41.097 1   10.188 ? 901  A1ILR A H8   1 
HETATM 4423 H H9   . A1ILR B 2 .   ? 20.437 39.352 39.165 1   10.184 ? 901  A1ILR A H9   1 
HETATM 4424 H H1   . A1ILR B 2 .   ? 24.342 37.623 47.073 0   30     ? 901  A1ILR A H1   1 
HETATM 4425 H HN7  . A1ILR B 2 .   ? 20.822 39.411 42.897 1   10.331 ? 901  A1ILR A HN7  1 
HETATM 4426 H HN10 . A1ILR B 2 .   ? 21.625 40.982 41.327 1   9.897  ? 901  A1ILR A HN10 1 
HETATM 4427 H HN11 . A1ILR B 2 .   ? 20.088 41.083 40.634 1   9.892  ? 901  A1ILR A HN11 1 
HETATM 4428 H HN12 . A1ILR B 2 .   ? 21.446 41.511 39.741 1   9.897  ? 901  A1ILR A HN12 1 
HETATM 4429 S S    . SO4   C 3 .   ? 16.449 52.267 47.717 1   20.925 ? 902  SO4   A S    1 
HETATM 4430 O O1   . SO4   C 3 .   ? 16.104 50.997 47.066 1   18.589 ? 902  SO4   A O1   1 
HETATM 4431 O O2   . SO4   C 3 .   ? 16.728 53.289 46.733 1   18.443 ? 902  SO4   A O2   1 
HETATM 4432 O O3   . SO4   C 3 .   ? 15.316 52.67  48.525 1   19.648 ? 902  SO4   A O3   1 
HETATM 4433 O O4   . SO4   C 3 .   ? 17.625 52.1   48.621 1   18.527 ? 902  SO4   A O4   1 
HETATM 4434 O O    . HOH   D 4 .   ? -2.91  41.936 44.222 1   31.496 ? 1001 HOH   A O    1 
HETATM 4435 O O    . HOH   D 4 .   ? 3.432  49.13  28.244 1   27.398 ? 1002 HOH   A O    1 
HETATM 4436 O O    . HOH   D 4 .   ? 7.884  41.826 24.012 1   34.372 ? 1003 HOH   A O    1 
HETATM 4437 O O    . HOH   D 4 .   ? 0.92   36.511 37.945 1   36.417 ? 1004 HOH   A O    1 
HETATM 4438 O O    . HOH   D 4 .   ? 5.775  42.926 37.87  1   27.87  ? 1005 HOH   A O    1 
HETATM 4439 O O    . HOH   D 4 .   ? 13.608 45.32  53.645 1   25.663 ? 1006 HOH   A O    1 
HETATM 4440 O O    . HOH   D 4 .   ? 41.039 46.931 36.335 1   34.658 ? 1007 HOH   A O    1 
HETATM 4441 O O    . HOH   D 4 .   ? 22.357 59.934 23.506 1   41.283 ? 1008 HOH   A O    1 
HETATM 4442 O O    . HOH   D 4 .   ? 7.469  43.83  31.302 1   18.277 ? 1009 HOH   A O    1 
HETATM 4443 O O    . HOH   D 4 .   ? -2.248 33.425 51.172 1   32.711 ? 1010 HOH   A O    1 
HETATM 4444 O O    . HOH   D 4 .   ? 20.829 43.326 56.545 1   33.369 ? 1011 HOH   A O    1 
HETATM 4445 O O    . HOH   D 4 .   ? 18.271 58.766 25.01  1   23.222 ? 1012 HOH   A O    1 
HETATM 4446 O O    . HOH   D 4 .   ? 6.591  60.798 36.85  1   24.042 ? 1013 HOH   A O    1 
HETATM 4447 O O    . HOH   D 4 .   ? 24.216 47.157 34.871 1   12.978 ? 1014 HOH   A O    1 
HETATM 4448 O O    . HOH   D 4 .   ? 35.834 32.83  31.907 1   25.607 ? 1015 HOH   A O    1 
HETATM 4449 O O    . HOH   D 4 .   ? 4.348  47.526 37.138 1   18.205 ? 1016 HOH   A O    1 
HETATM 4450 O O    . HOH   D 4 .   ? 25.615 56.833 48.463 1   14.348 ? 1017 HOH   A O    1 
HETATM 4451 O O    . HOH   D 4 .   ? 29.934 49.575 19.774 1   35.208 ? 1018 HOH   A O    1 
HETATM 4452 O O    . HOH   D 4 .   ? 34.49  58.762 39.082 1   21.104 ? 1019 HOH   A O    1 
HETATM 4453 O O    . HOH   D 4 .   ? 15.58  55.045 49.52  1   22.64  ? 1020 HOH   A O    1 
HETATM 4454 O O    . HOH   D 4 .   ? 12.092 47.549 45.638 1   17.082 ? 1021 HOH   A O    1 
HETATM 4455 O O    . HOH   D 4 .   ? 38.556 51.91  33.9   1   34.92  ? 1022 HOH   A O    1 
HETATM 4456 O O    . HOH   D 4 .   ? 19.305 39.871 21.731 1   20.424 ? 1023 HOH   A O    1 
HETATM 4457 O O    . HOH   D 4 .   ? 13.924 50.148 48.399 1   30.805 ? 1024 HOH   A O    1 
HETATM 4458 O O    . HOH   D 4 .   ? 35.606 57.935 32.331 1   23.791 ? 1025 HOH   A O    1 
HETATM 4459 O O    . HOH   D 4 .   ? 6.087  29.84  36.676 1   17.376 ? 1026 HOH   A O    1 
HETATM 4460 O O    . HOH   D 4 .   ? 34.168 56.351 42.587 1   33.738 ? 1027 HOH   A O    1 
HETATM 4461 O O    . HOH   D 4 .   ? 3.713  49.342 32.173 1   31.572 ? 1028 HOH   A O    1 
HETATM 4462 O O    . HOH   D 4 .   ? 15.17  52.08  51.067 1   23.415 ? 1029 HOH   A O    1 
HETATM 4463 O O    . HOH   D 4 .   ? 34.427 54.144 39.952 1   21.84  ? 1030 HOH   A O    1 
HETATM 4464 O O    . HOH   D 4 .   ? 25.489 43.091 19.891 1   28.08  ? 1031 HOH   A O    1 
HETATM 4465 O O    . HOH   D 4 .   ? 10.054 26.552 60.246 1   44.741 ? 1032 HOH   A O    1 
HETATM 4466 O O    . HOH   D 4 .   ? 17.282 48.669 47.375 1   18.131 ? 1033 HOH   A O    1 
HETATM 4467 O O    . HOH   D 4 .   ? 27.397 30.448 26.877 1   35.579 ? 1034 HOH   A O    1 
HETATM 4468 O O    . HOH   D 4 .   ? 23.355 43.003 44.49  1   8.673  ? 1035 HOH   A O    1 
HETATM 4469 O O    . HOH   D 4 .   ? 8.813  59.296 32.983 1   23.069 ? 1036 HOH   A O    1 
HETATM 4470 O O    . HOH   D 4 .   ? 18.021 51.334 21.655 1   16.927 ? 1037 HOH   A O    1 
HETATM 4471 O O    . HOH   D 4 .   ? 29.875 57.181 42.301 1   17.39  ? 1038 HOH   A O    1 
HETATM 4472 O O    . HOH   D 4 .   ? 16.657 38.379 27.045 1   20.58  ? 1039 HOH   A O    1 
HETATM 4473 O O    . HOH   D 4 .   ? 5.165  56.503 38.82  1   34.711 ? 1040 HOH   A O    1 
HETATM 4474 O O    . HOH   D 4 .   ? 2.816  48.827 39.074 1   28.02  ? 1041 HOH   A O    1 
HETATM 4475 O O    . HOH   D 4 .   ? 14.427 38.051 33.067 1   10.871 ? 1042 HOH   A O    1 
HETATM 4476 O O    . HOH   D 4 .   ? 0.484  53.696 38.254 1   28.844 ? 1043 HOH   A O    1 
HETATM 4477 O O    . HOH   D 4 .   ? 31.818 46.061 21.063 1   22.676 ? 1044 HOH   A O    1 
HETATM 4478 O O    . HOH   D 4 .   ? 31.42  49.329 42.658 1   17.907 ? 1045 HOH   A O    1 
HETATM 4479 O O    . HOH   D 4 .   ? 14.825 63.35  47.363 1   23.5   ? 1046 HOH   A O    1 
HETATM 4480 O O    . HOH   D 4 .   ? 15.156 37.421 53.82  1   22.428 ? 1047 HOH   A O    1 
HETATM 4481 O O    . HOH   D 4 .   ? 15.997 46.533 48.636 1   14.83  ? 1048 HOH   A O    1 
HETATM 4482 O O    . HOH   D 4 .   ? 38.237 48.308 27.931 1   30.272 ? 1049 HOH   A O    1 
HETATM 4483 O O    . HOH   D 4 .   ? 20.067 59.783 47.159 1   10.972 ? 1050 HOH   A O    1 
HETATM 4484 O O    . HOH   D 4 .   ? 22.999 46.868 21.578 1   17.418 ? 1051 HOH   A O    1 
HETATM 4485 O O    . HOH   D 4 .   ? 19.717 46.393 18.566 1   30.367 ? 1052 HOH   A O    1 
HETATM 4486 O O    . HOH   D 4 .   ? 3.9    29.435 47.012 1   19.742 ? 1053 HOH   A O    1 
HETATM 4487 O O    . HOH   D 4 .   ? 11.899 54.321 31.171 1   9.266  ? 1054 HOH   A O    1 
HETATM 4488 O O    . HOH   D 4 .   ? 30.526 22.69  28.842 1   26.045 ? 1055 HOH   A O    1 
HETATM 4489 O O    . HOH   D 4 .   ? 6.836  25.846 38.505 1   28.988 ? 1056 HOH   A O    1 
HETATM 4490 O O    . HOH   D 4 .   ? 0.294  48.2   42.365 1   20.824 ? 1057 HOH   A O    1 
HETATM 4491 O O    . HOH   D 4 .   ? 4.58   42.173 34.095 1   38.203 ? 1058 HOH   A O    1 
HETATM 4492 O O    . HOH   D 4 .   ? 19.566 60.555 26.598 1   22.686 ? 1059 HOH   A O    1 
HETATM 4493 O O    . HOH   D 4 .   ? 27.442 54.501 45.088 1   10.357 ? 1060 HOH   A O    1 
HETATM 4494 O O    . HOH   D 4 .   ? 22.965 39.336 21.95  1   26.632 ? 1061 HOH   A O    1 
HETATM 4495 O O    . HOH   D 4 .   ? 25.679 32.789 26.717 1   29.86  ? 1062 HOH   A O    1 
HETATM 4496 O O    . HOH   D 4 .   ? 7.763  43.606 19.55  1   16.513 ? 1063 HOH   A O    1 
HETATM 4497 O O    . HOH   D 4 .   ? 4.103  44.91  33.127 1   24.676 ? 1064 HOH   A O    1 
HETATM 4498 O O    . HOH   D 4 .   ? 23.278 58.826 37.093 1   15.999 ? 1065 HOH   A O    1 
HETATM 4499 O O    . HOH   D 4 .   ? 35.853 19.900 24.267 1   14.105 ? 1066 HOH   A O    1 
HETATM 4500 O O    . HOH   D 4 .   ? 26.19  35.526 26.882 1   17.394 ? 1067 HOH   A O    1 
HETATM 4501 O O    . HOH   D 4 .   ? 10.311 35.1   31.778 1   32.255 ? 1068 HOH   A O    1 
HETATM 4502 O O    . HOH   D 4 .   ? 2.607  58.123 44.323 1   17.562 ? 1069 HOH   A O    1 
HETATM 4503 O O    . HOH   D 4 .   ? 4.8    30.415 49.61  1   17.354 ? 1070 HOH   A O    1 
HETATM 4504 O O    . HOH   D 4 .   ? 5.765  36.957 21.814 1   45.567 ? 1071 HOH   A O    1 
HETATM 4505 O O    . HOH   D 4 .   ? 3.664  65.914 41.746 1   17.823 ? 1072 HOH   A O    1 
HETATM 4506 O O    . HOH   D 4 .   ? 22.517 30.464 29.243 1   37.923 ? 1073 HOH   A O    1 
HETATM 4507 O O    . HOH   D 4 .   ? 30.529 33.907 26.328 1   33.039 ? 1074 HOH   A O    1 
HETATM 4508 O O    . HOH   D 4 .   ? 4.062  40.723 36.749 1   32.114 ? 1075 HOH   A O    1 
HETATM 4509 O O    . HOH   D 4 .   ? 5.083  49.639 25.821 1   12.572 ? 1076 HOH   A O    1 
HETATM 4510 O O    . HOH   D 4 .   ? 19.859 52.394 47.085 1   10.042 ? 1077 HOH   A O    1 
HETATM 4511 O O    . HOH   D 4 .   ? 28.381 44.629 46.123 1   20.118 ? 1078 HOH   A O    1 
HETATM 4512 O O    . HOH   D 4 .   ? 12.18  41.861 52.299 1   19.206 ? 1079 HOH   A O    1 
HETATM 4513 O O    . HOH   D 4 .   ? 7.113  50.359 38.419 1   8.326  ? 1080 HOH   A O    1 
HETATM 4514 O O    . HOH   D 4 .   ? 28.299 35.772 24.941 1   27.341 ? 1081 HOH   A O    1 
HETATM 4515 O O    . HOH   D 4 .   ? 19.018 53.675 43.932 1   13.092 ? 1082 HOH   A O    1 
HETATM 4516 O O    . HOH   D 4 .   ? 12.371 27.994 34.622 1   31.654 ? 1083 HOH   A O    1 
HETATM 4517 O O    . HOH   D 4 .   ? 5.454  41.875 30.217 1   22.359 ? 1084 HOH   A O    1 
HETATM 4518 O O    . HOH   D 4 .   ? 34.409 38.081 20.687 1   40.922 ? 1085 HOH   A O    1 
HETATM 4519 O O    . HOH   D 4 .   ? 9.331  61.842 30.466 1   17.912 ? 1086 HOH   A O    1 
HETATM 4520 O O    . HOH   D 4 .   ? 10.292 57.712 32.059 1   13.678 ? 1087 HOH   A O    1 
HETATM 4521 O O    . HOH   D 4 .   ? 5.815  36.797 37.463 1   16.901 ? 1088 HOH   A O    1 
HETATM 4522 O O    . HOH   D 4 .   ? 18.919 27.161 61.114 1   31.378 ? 1089 HOH   A O    1 
HETATM 4523 O O    . HOH   D 4 .   ? 7.469  56.856 47.514 1   10.747 ? 1090 HOH   A O    1 
HETATM 4524 O O    . HOH   D 4 .   ? 3.079  54.931 19.698 1   19.826 ? 1091 HOH   A O    1 
HETATM 4525 O O    . HOH   D 4 .   ? 9.041  29.869 60.936 1   44.572 ? 1092 HOH   A O    1 
HETATM 4526 O O    . HOH   D 4 .   ? -0.847 47.32  17.596 1   28.391 ? 1093 HOH   A O    1 
HETATM 4527 O O    . HOH   D 4 .   ? 36.718 43.071 30.756 1   22.606 ? 1094 HOH   A O    1 
HETATM 4528 O O    . HOH   D 4 .   ? 37.26  40.789 26.676 1   33.001 ? 1095 HOH   A O    1 
HETATM 4529 O O    . HOH   D 4 .   ? 16.187 32.84  30.855 1   26.538 ? 1096 HOH   A O    1 
HETATM 4530 O O    . HOH   D 4 .   ? 5.329  56.463 26.458 1   15.867 ? 1097 HOH   A O    1 
HETATM 4531 O O    . HOH   D 4 .   ? 11.231 48.438 50.616 1   21.099 ? 1098 HOH   A O    1 
HETATM 4532 O O    . HOH   D 4 .   ? 29.741 61.885 34.068 1   26.389 ? 1099 HOH   A O    1 
HETATM 4533 O O    . HOH   D 4 .   ? 22.365 30.992 40.885 1   24.67  ? 1100 HOH   A O    1 
HETATM 4534 O O    . HOH   D 4 .   ? 2.289  48.856 47.676 1   8.593  ? 1101 HOH   A O    1 
HETATM 4535 O O    . HOH   D 4 .   ? 17.332 34.883 34.085 1   9.672  ? 1102 HOH   A O    1 
HETATM 4536 O O    . HOH   D 4 .   ? 13.45  47.506 47.952 1   15.328 ? 1103 HOH   A O    1 
HETATM 4537 O O    . HOH   D 4 .   ? 16.718 36.213 56.018 1   27.203 ? 1104 HOH   A O    1 
HETATM 4538 O O    . HOH   D 4 .   ? 28.032 35.261 38.667 1   20.163 ? 1105 HOH   A O    1 
HETATM 4539 O O    . HOH   D 4 .   ? 18.701 37.397 20.601 1   24.214 ? 1106 HOH   A O    1 
HETATM 4540 O O    . HOH   D 4 .   ? 15.446 36.752 31.08  1   15.494 ? 1107 HOH   A O    1 
HETATM 4541 O O    . HOH   D 4 .   ? 32.491 36.064 26.579 1   15.318 ? 1108 HOH   A O    1 
HETATM 4542 O O    . HOH   D 4 .   ? 18.927 60.712 44.936 1   16.442 ? 1109 HOH   A O    1 
HETATM 4543 O O    . HOH   D 4 .   ? 38.521 39.858 31.817 1   26.787 ? 1110 HOH   A O    1 
HETATM 4544 O O    . HOH   D 4 .   ? 19.805 21.06  58.112 1   38.254 ? 1111 HOH   A O    1 
HETATM 4545 O O    . HOH   D 4 .   ? 16.563 33.825 25.722 1   19.455 ? 1112 HOH   A O    1 
HETATM 4546 O O    . HOH   D 4 .   ? 23.698 35.925 25.405 1   18.332 ? 1113 HOH   A O    1 
HETATM 4547 O O    . HOH   D 4 .   ? 33.268 48.183 28.082 1   17.709 ? 1114 HOH   A O    1 
HETATM 4548 O O    . HOH   D 4 .   ? 14.955 53.847 21.019 1   17.841 ? 1115 HOH   A O    1 
HETATM 4549 O O    . HOH   D 4 .   ? 17.661 41.898 39.284 1   10.886 ? 1116 HOH   A O    1 
HETATM 4550 O O    . HOH   D 4 .   ? -0.702 55.823 30.642 1   17.328 ? 1117 HOH   A O    1 
HETATM 4551 O O    . HOH   D 4 .   ? 17.258 65.364 41.071 1   30.218 ? 1118 HOH   A O    1 
HETATM 4552 O O    . HOH   D 4 .   ? 21.669 63.186 38.048 1   17.07  ? 1119 HOH   A O    1 
HETATM 4553 O O    . HOH   D 4 .   ? 10.146 49.151 15.808 1   30.217 ? 1120 HOH   A O    1 
HETATM 4554 O O    . HOH   D 4 .   ? 15.998 59.946 32.561 1   17.531 ? 1121 HOH   A O    1 
HETATM 4555 O O    . HOH   D 4 .   ? 20.126 34.672 35.248 1   9.731  ? 1122 HOH   A O    1 
HETATM 4556 O O    . HOH   D 4 .   ? 12.65  62.446 45.676 1   27.288 ? 1123 HOH   A O    1 
HETATM 4557 O O    . HOH   D 4 .   ? 37.475 55.312 33.583 1   29.363 ? 1124 HOH   A O    1 
HETATM 4558 O O    . HOH   D 4 .   ? 33.562 34.825 28.828 1   17.302 ? 1125 HOH   A O    1 
HETATM 4559 O O    . HOH   D 4 .   ? 24.754 38.612 54.844 1   20.59  ? 1126 HOH   A O    1 
HETATM 4560 O O    . HOH   D 4 .   ? 8.588  44.902 16.49  1   23.321 ? 1127 HOH   A O    1 
HETATM 4561 O O    . HOH   D 4 .   ? 15.196 47.17  51.244 1   33.922 ? 1128 HOH   A O    1 
HETATM 4562 O O    . HOH   D 4 .   ? 36.508 23.808 23.345 1   32.799 ? 1129 HOH   A O    1 
HETATM 4563 O O    . HOH   D 4 .   ? 5.52   58.148 44.478 1   26.171 ? 1130 HOH   A O    1 
HETATM 4564 O O    . HOH   D 4 .   ? 19.573 41.886 19.485 1   28.46  ? 1131 HOH   A O    1 
HETATM 4565 O O    . HOH   D 4 .   ? 6.613  49.082 49.345 1   11.402 ? 1132 HOH   A O    1 
HETATM 4566 O O    . HOH   D 4 .   ? 30.382 29.882 26.819 1   53.488 ? 1133 HOH   A O    1 
HETATM 4567 O O    . HOH   D 4 .   ? 4.021  49.131 23.143 1   16.189 ? 1134 HOH   A O    1 
HETATM 4568 O O    . HOH   D 4 .   ? 10.508 41.164 38.376 1   27.182 ? 1135 HOH   A O    1 
HETATM 4569 O O    . HOH   D 4 .   ? 9.47   49.268 48.734 1   16.212 ? 1136 HOH   A O    1 
HETATM 4570 O O    . HOH   D 4 .   ? 33.474 43.923 43.808 1   50.07  ? 1137 HOH   A O    1 
HETATM 4571 O O    . HOH   D 4 .   ? -2.785 53.197 45.616 1   24.841 ? 1138 HOH   A O    1 
HETATM 4572 O O    . HOH   D 4 .   ? 26.46  50.165 17.723 1   46.193 ? 1139 HOH   A O    1 
HETATM 4573 O O    . HOH   D 4 .   ? 13.62  57.265 23.716 1   44.001 ? 1140 HOH   A O    1 
HETATM 4574 O O    . HOH   D 4 .   ? -0.988 56.189 44.554 1   32.268 ? 1141 HOH   A O    1 
HETATM 4575 O O    . HOH   D 4 .   ? -0.16  54.723 21.974 1   31.55  ? 1142 HOH   A O    1 
HETATM 4576 O O    . HOH   D 4 .   ? 17.891 48.347 19.39  1   30.525 ? 1143 HOH   A O    1 
HETATM 4577 O O    . HOH   D 4 .   ? 22.405 46.517 18.957 1   31.702 ? 1144 HOH   A O    1 
HETATM 4578 O O    . HOH   D 4 .   ? 24.153 62.508 36.846 1   30.123 ? 1145 HOH   A O    1 
HETATM 4579 O O    . HOH   D 4 .   ? 15.38  39.254 29.308 1   11.179 ? 1146 HOH   A O    1 
HETATM 4580 O O    . HOH   D 4 .   ? 12.185 56.123 48.320 1   41.909 ? 1147 HOH   A O    1 
HETATM 4581 O O    . HOH   D 4 .   ? -1.844 55.305 41.722 1   38.32  ? 1148 HOH   A O    1 
HETATM 4582 O O    . HOH   D 4 .   ? 23.568 47.142 50.281 1   32.307 ? 1149 HOH   A O    1 
HETATM 4583 O O    . HOH   D 4 .   ? -3.159 50.407 43.183 1   28.638 ? 1150 HOH   A O    1 
HETATM 4584 O O    . HOH   D 4 .   ? 8.635  28.274 34.419 1   36.325 ? 1151 HOH   A O    1 
HETATM 4585 O O    . HOH   D 4 .   ? 15.478 36.727 35.43  1   14.392 ? 1152 HOH   A O    1 
HETATM 4586 O O    . HOH   D 4 .   ? 40.501 35.223 37.593 1   34.902 ? 1153 HOH   A O    1 
HETATM 4587 O O    . HOH   D 4 .   ? 35.087 47.18  39.579 1   19.6   ? 1154 HOH   A O    1 
HETATM 4588 O O    . HOH   D 4 .   ? 12.134 37.995 34.781 1   13.932 ? 1155 HOH   A O    1 
HETATM 4589 O O    . HOH   D 4 .   ? 36.311 41.407 23.188 1   41.728 ? 1156 HOH   A O    1 
HETATM 4590 O O    . HOH   D 4 .   ? 18.258 49.456 50.8   1   48.071 ? 1157 HOH   A O    1 
HETATM 4591 O O    . HOH   D 4 .   ? 16.867 43.594 56.812 1   29.209 ? 1158 HOH   A O    1 
HETATM 4592 O O    . HOH   D 4 .   ? 23.229 28.415 38.226 1   38.009 ? 1159 HOH   A O    1 
HETATM 4593 O O    . HOH   D 4 .   ? 3.56   36.989 39.023 1   26.538 ? 1160 HOH   A O    1 
HETATM 4594 O O    . HOH   D 4 .   ? 14.690 61.671 51.400 1   41.768 ? 1161 HOH   A O    1 
HETATM 4595 O O    . HOH   D 4 .   ? 29.927 32.716 38.433 1   28.213 ? 1162 HOH   A O    1 
HETATM 4596 O O    . HOH   D 4 .   ? 39.963 44.825 28.96  1   42.471 ? 1163 HOH   A O    1 
HETATM 4597 O O    . HOH   D 4 .   ? 21.056 57.095 21.26  1   22.579 ? 1164 HOH   A O    1 
HETATM 4598 O O    . HOH   D 4 .   ? 10.591 40.666 35.512 1   10.967 ? 1165 HOH   A O    1 
HETATM 4599 O O    . HOH   D 4 .   ? 9.361  48.342 46.265 1   13.841 ? 1166 HOH   A O    1 
HETATM 4600 O O    . HOH   D 4 .   ? 29.689 24.017 32.816 1   32.695 ? 1167 HOH   A O    1 
HETATM 4601 O O    . HOH   D 4 .   ? 40.469 37.251 35.215 1   53.236 ? 1168 HOH   A O    1 
HETATM 4602 O O    . HOH   D 4 .   ? 28.464 46.903 46.156 1   14.009 ? 1169 HOH   A O    1 
HETATM 4603 O O    . HOH   D 4 .   ? 3.992  28.395 37.894 1   35.485 ? 1170 HOH   A O    1 
HETATM 4604 O O    . HOH   D 4 .   ? 9.829  56.36  49.154 1   18.97  ? 1171 HOH   A O    1 
HETATM 4605 O O    . HOH   D 4 .   ? 29.938 64.355 39.897 1   34.004 ? 1172 HOH   A O    1 
HETATM 4606 O O    . HOH   D 4 .   ? 6.94   39.531 37.64  1   34.275 ? 1173 HOH   A O    1 
HETATM 4607 O O    . HOH   D 4 .   ? 24.974 65.12  39.938 1   29.765 ? 1174 HOH   A O    1 
HETATM 4608 O O    . HOH   D 4 .   ? 27.247 42.846 17.889 1   37.777 ? 1175 HOH   A O    1 
HETATM 4609 O O    . HOH   D 4 .   ? 14.529 49.275 44.668 1   21.235 ? 1176 HOH   A O    1 
HETATM 4610 O O    . HOH   D 4 .   ? 31.179 40.705 19.115 1   47.984 ? 1177 HOH   A O    1 
HETATM 4611 O O    . HOH   D 4 .   ? 36.497 41.847 49.916 1   30.935 ? 1178 HOH   A O    1 
HETATM 4612 O O    . HOH   D 4 .   ? 38.849 32.232 32.421 1   33.407 ? 1179 HOH   A O    1 
HETATM 4613 O O    . HOH   D 4 .   ? 41.382 34.56  34.779 1   52.569 ? 1180 HOH   A O    1 
HETATM 4614 O O    . HOH   D 4 .   ? 6.722  38.56  32.907 1   28.288 ? 1181 HOH   A O    1 
HETATM 4615 O O    . HOH   D 4 .   ? -3.411 59.918 37.838 1   38.438 ? 1182 HOH   A O    1 
HETATM 4616 O O    . HOH   D 4 .   ? 6.139  33.731 34.029 1   29.691 ? 1183 HOH   A O    1 
HETATM 4617 O O    . HOH   D 4 .   ? 21.145 62.042 24.988 1   29.39  ? 1184 HOH   A O    1 
HETATM 4618 O O    . HOH   D 4 .   ? 27.172 48.171 48.186 1   20.128 ? 1185 HOH   A O    1 
HETATM 4619 O O    . HOH   D 4 .   ? 30.943 37.951 19.848 1   38.75  ? 1186 HOH   A O    1 
HETATM 4620 O O    . HOH   D 4 .   ? 26.361 46.987 50.119 1   23.63  ? 1187 HOH   A O    1 
HETATM 4621 O O    . HOH   D 4 .   ? 32.818 59.918 41.212 1   30.953 ? 1188 HOH   A O    1 
HETATM 4622 O O    . HOH   D 4 .   ? 13.712 60.429 34.302 1   31.27  ? 1189 HOH   A O    1 
HETATM 4623 O O    . HOH   D 4 .   ? 35.107 36.523 25.478 1   26.976 ? 1190 HOH   A O    1 
HETATM 4624 O O    . HOH   D 4 .   ? 7.36   40.976 21.086 1   27.258 ? 1191 HOH   A O    1 
HETATM 4625 O O    . HOH   D 4 .   ? 9.007  60.508 35.677 1   33.797 ? 1192 HOH   A O    1 
HETATM 4626 O O    . HOH   D 4 .   ? 34.677 45.136 21.514 1   38.522 ? 1193 HOH   A O    1 
HETATM 4627 O O    . HOH   D 4 .   ? 31.962 43.433 45.96  1   32.85  ? 1194 HOH   A O    1 
HETATM 4628 O O    . HOH   D 4 .   ? 18.49  19.194 49.749 1   51.729 ? 1195 HOH   A O    1 
HETATM 4629 O O    . HOH   D 4 .   ? 1.675  47.882 23.756 1   31.329 ? 1196 HOH   A O    1 
HETATM 4630 O O    . HOH   D 4 .   ? 27.999 57.052 44.428 1   11.492 ? 1197 HOH   A O    1 
HETATM 4631 O O    . HOH   D 4 .   ? 12.204 28.803 63.042 1   25.483 ? 1198 HOH   A O    1 
HETATM 4632 O O    . HOH   D 4 .   ? 9.27   46.733 14.891 1   32.142 ? 1199 HOH   A O    1 
HETATM 4633 O O    . HOH   D 4 .   ? 32.374 58.158 42.783 1   25.85  ? 1200 HOH   A O    1 
HETATM 4634 O O    . HOH   D 4 .   ? 23.916 33.722 23.634 1   32.788 ? 1201 HOH   A O    1 
HETATM 4635 O O    . HOH   D 4 .   ? 17.114 62.404 31.787 1   26.838 ? 1202 HOH   A O    1 
HETATM 4636 O O    . HOH   D 4 .   ? 11.555 37.221 30.876 1   31.835 ? 1203 HOH   A O    1 
HETATM 4637 O O    . HOH   D 4 .   ? 15.282 35.814 26.716 1   29.024 ? 1204 HOH   A O    1 
HETATM 4638 O O    . HOH   D 4 .   ? 15.398 59.205 25.238 1   37.612 ? 1205 HOH   A O    1 
HETATM 4639 O O    . HOH   D 4 .   ? -1.006 48.272 23.095 1   36.872 ? 1206 HOH   A O    1 
HETATM 4640 O O    . HOH   D 4 .   ? 37.915 42.654 28.706 1   25.298 ? 1207 HOH   A O    1 
HETATM 4641 O O    . HOH   D 4 .   ? 11.775 60.963 50.302 1   29.063 ? 1208 HOH   A O    1 
HETATM 4642 O O    . HOH   D 4 .   ? 7.692  34.914 32.136 1   37.471 ? 1209 HOH   A O    1 
HETATM 4643 O O    . HOH   D 4 .   ? 36.14  35.063 30.208 1   26.451 ? 1210 HOH   A O    1 
HETATM 4644 O O    . HOH   D 4 .   ? 14.224 34.974 29.45  1   21.239 ? 1211 HOH   A O    1 
HETATM 4645 O O    . HOH   D 4 .   ? 27.081 37.887 54.871 1   31.501 ? 1212 HOH   A O    1 
HETATM 4646 O O    . HOH   D 4 .   ? 30.697 48.463 45.23  1   17.197 ? 1213 HOH   A O    1 
HETATM 4647 O O    . HOH   D 4 .   ? 14.441 61.3   26.854 1   42.627 ? 1214 HOH   A O    1 
HETATM 4648 O O    . HOH   D 4 .   ? 32.654 54.715 21.121 1   40.538 ? 1215 HOH   A O    1 
HETATM 4649 O O    . HOH   D 4 .   ? 33.889 46.54  42.315 1   32.697 ? 1216 HOH   A O    1 
HETATM 4650 O O    . HOH   D 4 .   ? 37.893 37.431 30.244 1   31.755 ? 1217 HOH   A O    1 
HETATM 4651 O O    . HOH   D 4 .   ? 12.953 49.534 15.424 1   28.191 ? 1218 HOH   A O    1 
# 
