data_9GCM
# 
_entry.id   9GCM 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GCM         pdb_00009gcm 10.2210/pdb9gcm/pdb 
WWPDB D_1292140775 ?            ?                   
EMDB  EMD-51234    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-02-05 
2 'Structure model' 1 1 2025-02-19 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 2 'Structure model' em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation.page_first'     
3 2 'Structure model' '_em_admin.last_update'    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GCM 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of the U11 snRNP core' 
_pdbx_database_related.db_id          EMD-51234 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              wgalej@embl.fr 
_pdbx_contact_author.name_first         Wojciech 
_pdbx_contact_author.name_last          Galej 
_pdbx_contact_author.name_mi            P. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0501-0171 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhao, J.'    1 0000-0003-0501-0171 
'Galej, W.P.' 2 0000-0001-8859-5229 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Mol.Cell 
_citation.journal_id_ASTM           MOCEFL 
_citation.journal_id_CSD            2168 
_citation.journal_id_ISSN           1097-2765 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            85 
_citation.language                  ? 
_citation.page_first                652 
_citation.page_last                 ? 
_citation.title                     
;Structural basis of 5' splice site recognition by the minor spliceosome.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.molcel.2024.12.017 
_citation.pdbx_database_id_PubMed   39809272 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhao, J.'     1 ? 
primary 'Peter, D.'    2 ? 
primary 'Brandina, I.' 3 ? 
primary 'Liu, X.'      4 ? 
primary 'Galej, W.P.'  5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'U11 snRNA'                                              43505.629 1 ? ? ? ? 
2 polymer man 'U11/U12 small nuclear ribonucleoprotein 25 kDa protein' 15290.729 1 ? ? ? ? 
3 polymer man 'U11/U12 small nuclear ribonucleoprotein 35 kDa protein' 29514.471 1 ? ? ? ? 
4 polymer man 'Programmed cell death protein 7'                        54791.984 1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
2 'U11/U12 snRNP 25 kDa protein,U11/U12-25K,Minus-99 protein'                              
3 'U11/U12 snRNP 35 kDa protein,U11/U12-35K,Protein HM-1,U1 snRNP-binding protein homolog' 
4 ES18,hES18                                                                               
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 polyribonucleotide no no 
;AAAAAGGGCUUCUGUCGUGAGUGGCACACGUAGGGCAACUCGAUUGCUCUGCGUGCGGAAUCGACAUCAAGAGAUUUCGG
AAGCAUAAUUUUUUGGUAUUUGGGCAGCUGGUGAUCGUUGGUCCCGGCGCCCUUU
;
;AAAAAGGGCUUCUGUCGUGAGUGGCACACGUAGGGCAACUCGAUUGCUCUGCGUGCGGAAUCGACAUCAAGAGAUUUCGG
AAGCAUAAUUUUUUGGUAUUUGGGCAGCUGGUGAUCGUUGGUCCCGGCGCCCUUU
;
A ? 
2 'polypeptide(L)'   no no 
;MDVFQEGLAMVVQDPLLCDLPIQVTLEEVNSQIALEYGQAMTVRVCKMDGEVMPVVVVQSATVLDLKKAIQRYVQLKQER
EGGIQHISWSYVWRTYHLTSAGEKLTEDRKKLRDYGIRNRDEVSFIKKLRQK
;
;MDVFQEGLAMVVQDPLLCDLPIQVTLEEVNSQIALEYGQAMTVRVCKMDGEVMPVVVVQSATVLDLKKAIQRYVQLKQER
EGGIQHISWSYVWRTYHLTSAGEKLTEDRKKLRDYGIRNRDEVSFIKKLRQK
;
B ? 
3 'polypeptide(L)'   no no 
;MNDWMPIAKEYDPLKAGSIDGTDEDPHDRAVWRAMLARYVPNKGVIGDPLLTLFVARLNLQTKEDKLKEVFSRYGDIRRL
RLVRDLVTGFSKGYAFIEYKEERAVIKAYRDADGLVIDQHEIFVDYELERTLKGWIPRRLGGGLGGKKESGQLRFGGRDR
PFRKPINLPVVKNDLYREGKRERRERSRSRERHWDSRTRDRDHDRGREKRWQEREPTRVWPDNDWERERDFRDDRIKGRE
KKERGK
;
;MNDWMPIAKEYDPLKAGSIDGTDEDPHDRAVWRAMLARYVPNKGVIGDPLLTLFVARLNLQTKEDKLKEVFSRYGDIRRL
RLVRDLVTGFSKGYAFIEYKEERAVIKAYRDADGLVIDQHEIFVDYELERTLKGWIPRRLGGGLGGKKESGQLRFGGRDR
PFRKPINLPVVKNDLYREGKRERRERSRSRERHWDSRTRDRDHDRGREKRWQEREPTRVWPDNDWERERDFRDDRIKGRE
KKERGK
;
C ? 
4 'polypeptide(L)'   no no 
;MALPPFFGQGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGGGGAGAF
YPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRLRDRQWLEAVFGTPRRAGCP
VPQRTHAGPSLGEVRARLLRALRLVRRLRGLSQALREAEADGAAWVLLYSQTAPLRAELAERLQPLTQAAYVGEARRRLE
RVRRRRLRLRERAREREAEREAEAARAVEREQEIDRWRVKCVQEVEEKKREQELKAAADGVLSEVRKKQADTKRMVDILR
ALEKLRKLRKEAAARKGVCPPASADETFTHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERKRELEKKQRKEKEKI
LLQKREIESKLFGDPDEFPLAHLLEPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNFVPQGWVLPPLPSNDIWAT
AVKLH
;
;MALPPFFGQGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGGGGAGAF
YPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRLRDRQWLEAVFGTPRRAGCP
VPQRTHAGPSLGEVRARLLRALRLVRRLRGLSQALREAEADGAAWVLLYSQTAPLRAELAERLQPLTQAAYVGEARRRLE
RVRRRRLRLRERAREREAEREAEAARAVEREQEIDRWRVKCVQEVEEKKREQELKAAADGVLSEVRKKQADTKRMVDILR
ALEKLRKLRKEAAARKGVCPPASADETFTHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERKRELEKKQRKEKEKI
LLQKREIESKLFGDPDEFPLAHLLEPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNFVPQGWVLPPLPSNDIWAT
AVKLH
;
D ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   A   n 
1 2   A   n 
1 3   A   n 
1 4   A   n 
1 5   A   n 
1 6   G   n 
1 7   G   n 
1 8   G   n 
1 9   C   n 
1 10  U   n 
1 11  U   n 
1 12  C   n 
1 13  U   n 
1 14  G   n 
1 15  U   n 
1 16  C   n 
1 17  G   n 
1 18  U   n 
1 19  G   n 
1 20  A   n 
1 21  G   n 
1 22  U   n 
1 23  G   n 
1 24  G   n 
1 25  C   n 
1 26  A   n 
1 27  C   n 
1 28  A   n 
1 29  C   n 
1 30  G   n 
1 31  U   n 
1 32  A   n 
1 33  G   n 
1 34  G   n 
1 35  G   n 
1 36  C   n 
1 37  A   n 
1 38  A   n 
1 39  C   n 
1 40  U   n 
1 41  C   n 
1 42  G   n 
1 43  A   n 
1 44  U   n 
1 45  U   n 
1 46  G   n 
1 47  C   n 
1 48  U   n 
1 49  C   n 
1 50  U   n 
1 51  G   n 
1 52  C   n 
1 53  G   n 
1 54  U   n 
1 55  G   n 
1 56  C   n 
1 57  G   n 
1 58  G   n 
1 59  A   n 
1 60  A   n 
1 61  U   n 
1 62  C   n 
1 63  G   n 
1 64  A   n 
1 65  C   n 
1 66  A   n 
1 67  U   n 
1 68  C   n 
1 69  A   n 
1 70  A   n 
1 71  G   n 
1 72  A   n 
1 73  G   n 
1 74  A   n 
1 75  U   n 
1 76  U   n 
1 77  U   n 
1 78  C   n 
1 79  G   n 
1 80  G   n 
1 81  A   n 
1 82  A   n 
1 83  G   n 
1 84  C   n 
1 85  A   n 
1 86  U   n 
1 87  A   n 
1 88  A   n 
1 89  U   n 
1 90  U   n 
1 91  U   n 
1 92  U   n 
1 93  U   n 
1 94  U   n 
1 95  G   n 
1 96  G   n 
1 97  U   n 
1 98  A   n 
1 99  U   n 
1 100 U   n 
1 101 U   n 
1 102 G   n 
1 103 G   n 
1 104 G   n 
1 105 C   n 
1 106 A   n 
1 107 G   n 
1 108 C   n 
1 109 U   n 
1 110 G   n 
1 111 G   n 
1 112 U   n 
1 113 G   n 
1 114 A   n 
1 115 U   n 
1 116 C   n 
1 117 G   n 
1 118 U   n 
1 119 U   n 
1 120 G   n 
1 121 G   n 
1 122 U   n 
1 123 C   n 
1 124 C   n 
1 125 C   n 
1 126 G   n 
1 127 G   n 
1 128 C   n 
1 129 G   n 
1 130 C   n 
1 131 C   n 
1 132 C   n 
1 133 U   n 
1 134 U   n 
1 135 U   n 
2 1   MET n 
2 2   ASP n 
2 3   VAL n 
2 4   PHE n 
2 5   GLN n 
2 6   GLU n 
2 7   GLY n 
2 8   LEU n 
2 9   ALA n 
2 10  MET n 
2 11  VAL n 
2 12  VAL n 
2 13  GLN n 
2 14  ASP n 
2 15  PRO n 
2 16  LEU n 
2 17  LEU n 
2 18  CYS n 
2 19  ASP n 
2 20  LEU n 
2 21  PRO n 
2 22  ILE n 
2 23  GLN n 
2 24  VAL n 
2 25  THR n 
2 26  LEU n 
2 27  GLU n 
2 28  GLU n 
2 29  VAL n 
2 30  ASN n 
2 31  SER n 
2 32  GLN n 
2 33  ILE n 
2 34  ALA n 
2 35  LEU n 
2 36  GLU n 
2 37  TYR n 
2 38  GLY n 
2 39  GLN n 
2 40  ALA n 
2 41  MET n 
2 42  THR n 
2 43  VAL n 
2 44  ARG n 
2 45  VAL n 
2 46  CYS n 
2 47  LYS n 
2 48  MET n 
2 49  ASP n 
2 50  GLY n 
2 51  GLU n 
2 52  VAL n 
2 53  MET n 
2 54  PRO n 
2 55  VAL n 
2 56  VAL n 
2 57  VAL n 
2 58  VAL n 
2 59  GLN n 
2 60  SER n 
2 61  ALA n 
2 62  THR n 
2 63  VAL n 
2 64  LEU n 
2 65  ASP n 
2 66  LEU n 
2 67  LYS n 
2 68  LYS n 
2 69  ALA n 
2 70  ILE n 
2 71  GLN n 
2 72  ARG n 
2 73  TYR n 
2 74  VAL n 
2 75  GLN n 
2 76  LEU n 
2 77  LYS n 
2 78  GLN n 
2 79  GLU n 
2 80  ARG n 
2 81  GLU n 
2 82  GLY n 
2 83  GLY n 
2 84  ILE n 
2 85  GLN n 
2 86  HIS n 
2 87  ILE n 
2 88  SER n 
2 89  TRP n 
2 90  SER n 
2 91  TYR n 
2 92  VAL n 
2 93  TRP n 
2 94  ARG n 
2 95  THR n 
2 96  TYR n 
2 97  HIS n 
2 98  LEU n 
2 99  THR n 
2 100 SER n 
2 101 ALA n 
2 102 GLY n 
2 103 GLU n 
2 104 LYS n 
2 105 LEU n 
2 106 THR n 
2 107 GLU n 
2 108 ASP n 
2 109 ARG n 
2 110 LYS n 
2 111 LYS n 
2 112 LEU n 
2 113 ARG n 
2 114 ASP n 
2 115 TYR n 
2 116 GLY n 
2 117 ILE n 
2 118 ARG n 
2 119 ASN n 
2 120 ARG n 
2 121 ASP n 
2 122 GLU n 
2 123 VAL n 
2 124 SER n 
2 125 PHE n 
2 126 ILE n 
2 127 LYS n 
2 128 LYS n 
2 129 LEU n 
2 130 ARG n 
2 131 GLN n 
2 132 LYS n 
3 1   MET n 
3 2   ASN n 
3 3   ASP n 
3 4   TRP n 
3 5   MET n 
3 6   PRO n 
3 7   ILE n 
3 8   ALA n 
3 9   LYS n 
3 10  GLU n 
3 11  TYR n 
3 12  ASP n 
3 13  PRO n 
3 14  LEU n 
3 15  LYS n 
3 16  ALA n 
3 17  GLY n 
3 18  SER n 
3 19  ILE n 
3 20  ASP n 
3 21  GLY n 
3 22  THR n 
3 23  ASP n 
3 24  GLU n 
3 25  ASP n 
3 26  PRO n 
3 27  HIS n 
3 28  ASP n 
3 29  ARG n 
3 30  ALA n 
3 31  VAL n 
3 32  TRP n 
3 33  ARG n 
3 34  ALA n 
3 35  MET n 
3 36  LEU n 
3 37  ALA n 
3 38  ARG n 
3 39  TYR n 
3 40  VAL n 
3 41  PRO n 
3 42  ASN n 
3 43  LYS n 
3 44  GLY n 
3 45  VAL n 
3 46  ILE n 
3 47  GLY n 
3 48  ASP n 
3 49  PRO n 
3 50  LEU n 
3 51  LEU n 
3 52  THR n 
3 53  LEU n 
3 54  PHE n 
3 55  VAL n 
3 56  ALA n 
3 57  ARG n 
3 58  LEU n 
3 59  ASN n 
3 60  LEU n 
3 61  GLN n 
3 62  THR n 
3 63  LYS n 
3 64  GLU n 
3 65  ASP n 
3 66  LYS n 
3 67  LEU n 
3 68  LYS n 
3 69  GLU n 
3 70  VAL n 
3 71  PHE n 
3 72  SER n 
3 73  ARG n 
3 74  TYR n 
3 75  GLY n 
3 76  ASP n 
3 77  ILE n 
3 78  ARG n 
3 79  ARG n 
3 80  LEU n 
3 81  ARG n 
3 82  LEU n 
3 83  VAL n 
3 84  ARG n 
3 85  ASP n 
3 86  LEU n 
3 87  VAL n 
3 88  THR n 
3 89  GLY n 
3 90  PHE n 
3 91  SER n 
3 92  LYS n 
3 93  GLY n 
3 94  TYR n 
3 95  ALA n 
3 96  PHE n 
3 97  ILE n 
3 98  GLU n 
3 99  TYR n 
3 100 LYS n 
3 101 GLU n 
3 102 GLU n 
3 103 ARG n 
3 104 ALA n 
3 105 VAL n 
3 106 ILE n 
3 107 LYS n 
3 108 ALA n 
3 109 TYR n 
3 110 ARG n 
3 111 ASP n 
3 112 ALA n 
3 113 ASP n 
3 114 GLY n 
3 115 LEU n 
3 116 VAL n 
3 117 ILE n 
3 118 ASP n 
3 119 GLN n 
3 120 HIS n 
3 121 GLU n 
3 122 ILE n 
3 123 PHE n 
3 124 VAL n 
3 125 ASP n 
3 126 TYR n 
3 127 GLU n 
3 128 LEU n 
3 129 GLU n 
3 130 ARG n 
3 131 THR n 
3 132 LEU n 
3 133 LYS n 
3 134 GLY n 
3 135 TRP n 
3 136 ILE n 
3 137 PRO n 
3 138 ARG n 
3 139 ARG n 
3 140 LEU n 
3 141 GLY n 
3 142 GLY n 
3 143 GLY n 
3 144 LEU n 
3 145 GLY n 
3 146 GLY n 
3 147 LYS n 
3 148 LYS n 
3 149 GLU n 
3 150 SER n 
3 151 GLY n 
3 152 GLN n 
3 153 LEU n 
3 154 ARG n 
3 155 PHE n 
3 156 GLY n 
3 157 GLY n 
3 158 ARG n 
3 159 ASP n 
3 160 ARG n 
3 161 PRO n 
3 162 PHE n 
3 163 ARG n 
3 164 LYS n 
3 165 PRO n 
3 166 ILE n 
3 167 ASN n 
3 168 LEU n 
3 169 PRO n 
3 170 VAL n 
3 171 VAL n 
3 172 LYS n 
3 173 ASN n 
3 174 ASP n 
3 175 LEU n 
3 176 TYR n 
3 177 ARG n 
3 178 GLU n 
3 179 GLY n 
3 180 LYS n 
3 181 ARG n 
3 182 GLU n 
3 183 ARG n 
3 184 ARG n 
3 185 GLU n 
3 186 ARG n 
3 187 SER n 
3 188 ARG n 
3 189 SER n 
3 190 ARG n 
3 191 GLU n 
3 192 ARG n 
3 193 HIS n 
3 194 TRP n 
3 195 ASP n 
3 196 SER n 
3 197 ARG n 
3 198 THR n 
3 199 ARG n 
3 200 ASP n 
3 201 ARG n 
3 202 ASP n 
3 203 HIS n 
3 204 ASP n 
3 205 ARG n 
3 206 GLY n 
3 207 ARG n 
3 208 GLU n 
3 209 LYS n 
3 210 ARG n 
3 211 TRP n 
3 212 GLN n 
3 213 GLU n 
3 214 ARG n 
3 215 GLU n 
3 216 PRO n 
3 217 THR n 
3 218 ARG n 
3 219 VAL n 
3 220 TRP n 
3 221 PRO n 
3 222 ASP n 
3 223 ASN n 
3 224 ASP n 
3 225 TRP n 
3 226 GLU n 
3 227 ARG n 
3 228 GLU n 
3 229 ARG n 
3 230 ASP n 
3 231 PHE n 
3 232 ARG n 
3 233 ASP n 
3 234 ASP n 
3 235 ARG n 
3 236 ILE n 
3 237 LYS n 
3 238 GLY n 
3 239 ARG n 
3 240 GLU n 
3 241 LYS n 
3 242 LYS n 
3 243 GLU n 
3 244 ARG n 
3 245 GLY n 
3 246 LYS n 
4 1   MET n 
4 2   ALA n 
4 3   LEU n 
4 4   PRO n 
4 5   PRO n 
4 6   PHE n 
4 7   PHE n 
4 8   GLY n 
4 9   GLN n 
4 10  GLY n 
4 11  ARG n 
4 12  PRO n 
4 13  GLY n 
4 14  PRO n 
4 15  PRO n 
4 16  PRO n 
4 17  PRO n 
4 18  GLN n 
4 19  PRO n 
4 20  PRO n 
4 21  PRO n 
4 22  PRO n 
4 23  ALA n 
4 24  PRO n 
4 25  PHE n 
4 26  GLY n 
4 27  CYS n 
4 28  PRO n 
4 29  PRO n 
4 30  PRO n 
4 31  PRO n 
4 32  LEU n 
4 33  PRO n 
4 34  SER n 
4 35  PRO n 
4 36  ALA n 
4 37  PHE n 
4 38  PRO n 
4 39  PRO n 
4 40  PRO n 
4 41  LEU n 
4 42  PRO n 
4 43  GLN n 
4 44  ARG n 
4 45  PRO n 
4 46  GLY n 
4 47  PRO n 
4 48  PHE n 
4 49  PRO n 
4 50  GLY n 
4 51  ALA n 
4 52  SER n 
4 53  ALA n 
4 54  PRO n 
4 55  PHE n 
4 56  LEU n 
4 57  GLN n 
4 58  PRO n 
4 59  PRO n 
4 60  LEU n 
4 61  ALA n 
4 62  LEU n 
4 63  GLN n 
4 64  PRO n 
4 65  ARG n 
4 66  ALA n 
4 67  SER n 
4 68  ALA n 
4 69  GLU n 
4 70  ALA n 
4 71  SER n 
4 72  ARG n 
4 73  GLY n 
4 74  GLY n 
4 75  GLY n 
4 76  GLY n 
4 77  ALA n 
4 78  GLY n 
4 79  ALA n 
4 80  PHE n 
4 81  TYR n 
4 82  PRO n 
4 83  VAL n 
4 84  PRO n 
4 85  PRO n 
4 86  PRO n 
4 87  PRO n 
4 88  LEU n 
4 89  PRO n 
4 90  PRO n 
4 91  PRO n 
4 92  PRO n 
4 93  PRO n 
4 94  GLN n 
4 95  CYS n 
4 96  ARG n 
4 97  PRO n 
4 98  PHE n 
4 99  PRO n 
4 100 GLY n 
4 101 THR n 
4 102 ASP n 
4 103 ALA n 
4 104 GLY n 
4 105 GLU n 
4 106 ARG n 
4 107 PRO n 
4 108 ARG n 
4 109 PRO n 
4 110 PRO n 
4 111 PRO n 
4 112 PRO n 
4 113 GLY n 
4 114 PRO n 
4 115 GLY n 
4 116 PRO n 
4 117 PRO n 
4 118 TRP n 
4 119 SER n 
4 120 PRO n 
4 121 ARG n 
4 122 TRP n 
4 123 PRO n 
4 124 GLU n 
4 125 ALA n 
4 126 PRO n 
4 127 PRO n 
4 128 PRO n 
4 129 PRO n 
4 130 ALA n 
4 131 ASP n 
4 132 VAL n 
4 133 LEU n 
4 134 GLY n 
4 135 ASP n 
4 136 ALA n 
4 137 ALA n 
4 138 LEU n 
4 139 GLN n 
4 140 ARG n 
4 141 LEU n 
4 142 ARG n 
4 143 ASP n 
4 144 ARG n 
4 145 GLN n 
4 146 TRP n 
4 147 LEU n 
4 148 GLU n 
4 149 ALA n 
4 150 VAL n 
4 151 PHE n 
4 152 GLY n 
4 153 THR n 
4 154 PRO n 
4 155 ARG n 
4 156 ARG n 
4 157 ALA n 
4 158 GLY n 
4 159 CYS n 
4 160 PRO n 
4 161 VAL n 
4 162 PRO n 
4 163 GLN n 
4 164 ARG n 
4 165 THR n 
4 166 HIS n 
4 167 ALA n 
4 168 GLY n 
4 169 PRO n 
4 170 SER n 
4 171 LEU n 
4 172 GLY n 
4 173 GLU n 
4 174 VAL n 
4 175 ARG n 
4 176 ALA n 
4 177 ARG n 
4 178 LEU n 
4 179 LEU n 
4 180 ARG n 
4 181 ALA n 
4 182 LEU n 
4 183 ARG n 
4 184 LEU n 
4 185 VAL n 
4 186 ARG n 
4 187 ARG n 
4 188 LEU n 
4 189 ARG n 
4 190 GLY n 
4 191 LEU n 
4 192 SER n 
4 193 GLN n 
4 194 ALA n 
4 195 LEU n 
4 196 ARG n 
4 197 GLU n 
4 198 ALA n 
4 199 GLU n 
4 200 ALA n 
4 201 ASP n 
4 202 GLY n 
4 203 ALA n 
4 204 ALA n 
4 205 TRP n 
4 206 VAL n 
4 207 LEU n 
4 208 LEU n 
4 209 TYR n 
4 210 SER n 
4 211 GLN n 
4 212 THR n 
4 213 ALA n 
4 214 PRO n 
4 215 LEU n 
4 216 ARG n 
4 217 ALA n 
4 218 GLU n 
4 219 LEU n 
4 220 ALA n 
4 221 GLU n 
4 222 ARG n 
4 223 LEU n 
4 224 GLN n 
4 225 PRO n 
4 226 LEU n 
4 227 THR n 
4 228 GLN n 
4 229 ALA n 
4 230 ALA n 
4 231 TYR n 
4 232 VAL n 
4 233 GLY n 
4 234 GLU n 
4 235 ALA n 
4 236 ARG n 
4 237 ARG n 
4 238 ARG n 
4 239 LEU n 
4 240 GLU n 
4 241 ARG n 
4 242 VAL n 
4 243 ARG n 
4 244 ARG n 
4 245 ARG n 
4 246 ARG n 
4 247 LEU n 
4 248 ARG n 
4 249 LEU n 
4 250 ARG n 
4 251 GLU n 
4 252 ARG n 
4 253 ALA n 
4 254 ARG n 
4 255 GLU n 
4 256 ARG n 
4 257 GLU n 
4 258 ALA n 
4 259 GLU n 
4 260 ARG n 
4 261 GLU n 
4 262 ALA n 
4 263 GLU n 
4 264 ALA n 
4 265 ALA n 
4 266 ARG n 
4 267 ALA n 
4 268 VAL n 
4 269 GLU n 
4 270 ARG n 
4 271 GLU n 
4 272 GLN n 
4 273 GLU n 
4 274 ILE n 
4 275 ASP n 
4 276 ARG n 
4 277 TRP n 
4 278 ARG n 
4 279 VAL n 
4 280 LYS n 
4 281 CYS n 
4 282 VAL n 
4 283 GLN n 
4 284 GLU n 
4 285 VAL n 
4 286 GLU n 
4 287 GLU n 
4 288 LYS n 
4 289 LYS n 
4 290 ARG n 
4 291 GLU n 
4 292 GLN n 
4 293 GLU n 
4 294 LEU n 
4 295 LYS n 
4 296 ALA n 
4 297 ALA n 
4 298 ALA n 
4 299 ASP n 
4 300 GLY n 
4 301 VAL n 
4 302 LEU n 
4 303 SER n 
4 304 GLU n 
4 305 VAL n 
4 306 ARG n 
4 307 LYS n 
4 308 LYS n 
4 309 GLN n 
4 310 ALA n 
4 311 ASP n 
4 312 THR n 
4 313 LYS n 
4 314 ARG n 
4 315 MET n 
4 316 VAL n 
4 317 ASP n 
4 318 ILE n 
4 319 LEU n 
4 320 ARG n 
4 321 ALA n 
4 322 LEU n 
4 323 GLU n 
4 324 LYS n 
4 325 LEU n 
4 326 ARG n 
4 327 LYS n 
4 328 LEU n 
4 329 ARG n 
4 330 LYS n 
4 331 GLU n 
4 332 ALA n 
4 333 ALA n 
4 334 ALA n 
4 335 ARG n 
4 336 LYS n 
4 337 GLY n 
4 338 VAL n 
4 339 CYS n 
4 340 PRO n 
4 341 PRO n 
4 342 ALA n 
4 343 SER n 
4 344 ALA n 
4 345 ASP n 
4 346 GLU n 
4 347 THR n 
4 348 PHE n 
4 349 THR n 
4 350 HIS n 
4 351 HIS n 
4 352 LEU n 
4 353 GLN n 
4 354 ARG n 
4 355 LEU n 
4 356 ARG n 
4 357 LYS n 
4 358 LEU n 
4 359 ILE n 
4 360 LYS n 
4 361 LYS n 
4 362 ARG n 
4 363 SER n 
4 364 GLU n 
4 365 LEU n 
4 366 TYR n 
4 367 GLU n 
4 368 ALA n 
4 369 GLU n 
4 370 GLU n 
4 371 ARG n 
4 372 ALA n 
4 373 LEU n 
4 374 ARG n 
4 375 VAL n 
4 376 MET n 
4 377 LEU n 
4 378 GLU n 
4 379 GLY n 
4 380 GLU n 
4 381 GLN n 
4 382 GLU n 
4 383 GLU n 
4 384 GLU n 
4 385 ARG n 
4 386 LYS n 
4 387 ARG n 
4 388 GLU n 
4 389 LEU n 
4 390 GLU n 
4 391 LYS n 
4 392 LYS n 
4 393 GLN n 
4 394 ARG n 
4 395 LYS n 
4 396 GLU n 
4 397 LYS n 
4 398 GLU n 
4 399 LYS n 
4 400 ILE n 
4 401 LEU n 
4 402 LEU n 
4 403 GLN n 
4 404 LYS n 
4 405 ARG n 
4 406 GLU n 
4 407 ILE n 
4 408 GLU n 
4 409 SER n 
4 410 LYS n 
4 411 LEU n 
4 412 PHE n 
4 413 GLY n 
4 414 ASP n 
4 415 PRO n 
4 416 ASP n 
4 417 GLU n 
4 418 PHE n 
4 419 PRO n 
4 420 LEU n 
4 421 ALA n 
4 422 HIS n 
4 423 LEU n 
4 424 LEU n 
4 425 GLU n 
4 426 PRO n 
4 427 PHE n 
4 428 ARG n 
4 429 GLN n 
4 430 TYR n 
4 431 TYR n 
4 432 LEU n 
4 433 GLN n 
4 434 ALA n 
4 435 GLU n 
4 436 HIS n 
4 437 SER n 
4 438 LEU n 
4 439 PRO n 
4 440 ALA n 
4 441 LEU n 
4 442 ILE n 
4 443 GLN n 
4 444 ILE n 
4 445 ARG n 
4 446 HIS n 
4 447 ASP n 
4 448 TRP n 
4 449 ASP n 
4 450 GLN n 
4 451 TYR n 
4 452 LEU n 
4 453 VAL n 
4 454 PRO n 
4 455 SER n 
4 456 ASP n 
4 457 HIS n 
4 458 PRO n 
4 459 LYS n 
4 460 GLY n 
4 461 ASN n 
4 462 PHE n 
4 463 VAL n 
4 464 PRO n 
4 465 GLN n 
4 466 GLY n 
4 467 TRP n 
4 468 VAL n 
4 469 LEU n 
4 470 PRO n 
4 471 PRO n 
4 472 LEU n 
4 473 PRO n 
4 474 SER n 
4 475 ASN n 
4 476 ASP n 
4 477 ILE n 
4 478 TRP n 
4 479 ALA n 
4 480 THR n 
4 481 ALA n 
4 482 VAL n 
4 483 LYS n 
4 484 LEU n 
4 485 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 135 human ? ?                         ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 132 human ? 'SNRNP25, C16orf33'       ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 246 human ? 'SNRNP35, HM1, U1SNRNPBP' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 485 human ? PDCD7                     ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
ALA 'L-peptide linking' y ALANINE                      ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                     ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                   ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'              ? 'C4 H7 N O4'      133.103 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O8 P'  323.197 
CYS 'L-peptide linking' y CYSTEINE                     ? 'C3 H7 N O2 S'    121.158 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O8 P' 363.221 
GLN 'L-peptide linking' y GLUTAMINE                    ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'              ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                      ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                    ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                   ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                      ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                       ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                   ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                      ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                       ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                    ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                   ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                     ? 'C9 H11 N O3'     181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"   ? 'C9 H13 N2 O9 P'  324.181 
VAL 'L-peptide linking' y VALINE                       ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   A   1   1   ?   ?   ?   A . n 
A 1 2   A   2   2   ?   ?   ?   A . n 
A 1 3   A   3   3   ?   ?   ?   A . n 
A 1 4   A   4   4   ?   ?   ?   A . n 
A 1 5   A   5   5   ?   ?   ?   A . n 
A 1 6   G   6   6   ?   ?   ?   A . n 
A 1 7   G   7   7   ?   ?   ?   A . n 
A 1 8   G   8   8   ?   ?   ?   A . n 
A 1 9   C   9   9   ?   ?   ?   A . n 
A 1 10  U   10  10  ?   ?   ?   A . n 
A 1 11  U   11  11  11  U   U   A . n 
A 1 12  C   12  12  12  C   C   A . n 
A 1 13  U   13  13  13  U   U   A . n 
A 1 14  G   14  14  14  G   G   A . n 
A 1 15  U   15  15  15  U   U   A . n 
A 1 16  C   16  16  16  C   C   A . n 
A 1 17  G   17  17  17  G   G   A . n 
A 1 18  U   18  18  18  U   U   A . n 
A 1 19  G   19  19  19  G   G   A . n 
A 1 20  A   20  20  20  A   A   A . n 
A 1 21  G   21  21  21  G   G   A . n 
A 1 22  U   22  22  22  U   U   A . n 
A 1 23  G   23  23  23  G   G   A . n 
A 1 24  G   24  24  24  G   G   A . n 
A 1 25  C   25  25  25  C   C   A . n 
A 1 26  A   26  26  26  A   A   A . n 
A 1 27  C   27  27  27  C   C   A . n 
A 1 28  A   28  28  28  A   A   A . n 
A 1 29  C   29  29  29  C   C   A . n 
A 1 30  G   30  30  30  G   G   A . n 
A 1 31  U   31  31  31  U   U   A . n 
A 1 32  A   32  32  32  A   A   A . n 
A 1 33  G   33  33  33  G   G   A . n 
A 1 34  G   34  34  34  G   G   A . n 
A 1 35  G   35  35  35  G   G   A . n 
A 1 36  C   36  36  36  C   C   A . n 
A 1 37  A   37  37  37  A   A   A . n 
A 1 38  A   38  38  38  A   A   A . n 
A 1 39  C   39  39  ?   ?   ?   A . n 
A 1 40  U   40  40  ?   ?   ?   A . n 
A 1 41  C   41  41  ?   ?   ?   A . n 
A 1 42  G   42  42  ?   ?   ?   A . n 
A 1 43  A   43  43  ?   ?   ?   A . n 
A 1 44  U   44  44  44  U   U   A . n 
A 1 45  U   45  45  45  U   U   A . n 
A 1 46  G   46  46  46  G   G   A . n 
A 1 47  C   47  47  47  C   C   A . n 
A 1 48  U   48  48  48  U   U   A . n 
A 1 49  C   49  49  49  C   C   A . n 
A 1 50  U   50  50  50  U   U   A . n 
A 1 51  G   51  51  51  G   G   A . n 
A 1 52  C   52  52  52  C   C   A . n 
A 1 53  G   53  53  53  G   G   A . n 
A 1 54  U   54  54  54  U   U   A . n 
A 1 55  G   55  55  55  G   G   A . n 
A 1 56  C   56  56  56  C   C   A . n 
A 1 57  G   57  57  57  G   G   A . n 
A 1 58  G   58  58  58  G   G   A . n 
A 1 59  A   59  59  59  A   A   A . n 
A 1 60  A   60  60  60  A   A   A . n 
A 1 61  U   61  61  61  U   U   A . n 
A 1 62  C   62  62  62  C   C   A . n 
A 1 63  G   63  63  63  G   G   A . n 
A 1 64  A   64  64  64  A   A   A . n 
A 1 65  C   65  65  65  C   C   A . n 
A 1 66  A   66  66  66  A   A   A . n 
A 1 67  U   67  67  67  U   U   A . n 
A 1 68  C   68  68  68  C   C   A . n 
A 1 69  A   69  69  69  A   A   A . n 
A 1 70  A   70  70  70  A   A   A . n 
A 1 71  G   71  71  71  G   G   A . n 
A 1 72  A   72  72  72  A   A   A . n 
A 1 73  G   73  73  73  G   G   A . n 
A 1 74  A   74  74  74  A   A   A . n 
A 1 75  U   75  75  75  U   U   A . n 
A 1 76  U   76  76  76  U   U   A . n 
A 1 77  U   77  77  77  U   U   A . n 
A 1 78  C   78  78  78  C   C   A . n 
A 1 79  G   79  79  79  G   G   A . n 
A 1 80  G   80  80  80  G   G   A . n 
A 1 81  A   81  81  81  A   A   A . n 
A 1 82  A   82  82  ?   ?   ?   A . n 
A 1 83  G   83  83  ?   ?   ?   A . n 
A 1 84  C   84  84  ?   ?   ?   A . n 
A 1 85  A   85  85  ?   ?   ?   A . n 
A 1 86  U   86  86  ?   ?   ?   A . n 
A 1 87  A   87  87  ?   ?   ?   A . n 
A 1 88  A   88  88  ?   ?   ?   A . n 
A 1 89  U   89  89  ?   ?   ?   A . n 
A 1 90  U   90  90  ?   ?   ?   A . n 
A 1 91  U   91  91  ?   ?   ?   A . n 
A 1 92  U   92  92  ?   ?   ?   A . n 
A 1 93  U   93  93  ?   ?   ?   A . n 
A 1 94  U   94  94  ?   ?   ?   A . n 
A 1 95  G   95  95  ?   ?   ?   A . n 
A 1 96  G   96  96  ?   ?   ?   A . n 
A 1 97  U   97  97  ?   ?   ?   A . n 
A 1 98  A   98  98  ?   ?   ?   A . n 
A 1 99  U   99  99  ?   ?   ?   A . n 
A 1 100 U   100 100 ?   ?   ?   A . n 
A 1 101 U   101 101 ?   ?   ?   A . n 
A 1 102 G   102 102 ?   ?   ?   A . n 
A 1 103 G   103 103 ?   ?   ?   A . n 
A 1 104 G   104 104 ?   ?   ?   A . n 
A 1 105 C   105 105 ?   ?   ?   A . n 
A 1 106 A   106 106 ?   ?   ?   A . n 
A 1 107 G   107 107 ?   ?   ?   A . n 
A 1 108 C   108 108 ?   ?   ?   A . n 
A 1 109 U   109 109 ?   ?   ?   A . n 
A 1 110 G   110 110 ?   ?   ?   A . n 
A 1 111 G   111 111 ?   ?   ?   A . n 
A 1 112 U   112 112 ?   ?   ?   A . n 
A 1 113 G   113 113 ?   ?   ?   A . n 
A 1 114 A   114 114 ?   ?   ?   A . n 
A 1 115 U   115 115 ?   ?   ?   A . n 
A 1 116 C   116 116 ?   ?   ?   A . n 
A 1 117 G   117 117 ?   ?   ?   A . n 
A 1 118 U   118 118 ?   ?   ?   A . n 
A 1 119 U   119 119 ?   ?   ?   A . n 
A 1 120 G   120 120 ?   ?   ?   A . n 
A 1 121 G   121 121 ?   ?   ?   A . n 
A 1 122 U   122 122 ?   ?   ?   A . n 
A 1 123 C   123 123 ?   ?   ?   A . n 
A 1 124 C   124 124 ?   ?   ?   A . n 
A 1 125 C   125 125 ?   ?   ?   A . n 
A 1 126 G   126 126 ?   ?   ?   A . n 
A 1 127 G   127 127 ?   ?   ?   A . n 
A 1 128 C   128 128 ?   ?   ?   A . n 
A 1 129 G   129 129 ?   ?   ?   A . n 
A 1 130 C   130 130 ?   ?   ?   A . n 
A 1 131 C   131 131 ?   ?   ?   A . n 
A 1 132 C   132 132 ?   ?   ?   A . n 
A 1 133 U   133 133 ?   ?   ?   A . n 
A 1 134 U   134 134 ?   ?   ?   A . n 
A 1 135 U   135 135 ?   ?   ?   A . n 
B 2 1   MET 1   1   1   MET MET B . n 
B 2 2   ASP 2   2   2   ASP ASP B . n 
B 2 3   VAL 3   3   3   VAL VAL B . n 
B 2 4   PHE 4   4   4   PHE PHE B . n 
B 2 5   GLN 5   5   5   GLN GLN B . n 
B 2 6   GLU 6   6   6   GLU GLU B . n 
B 2 7   GLY 7   7   7   GLY GLY B . n 
B 2 8   LEU 8   8   8   LEU LEU B . n 
B 2 9   ALA 9   9   9   ALA ALA B . n 
B 2 10  MET 10  10  10  MET MET B . n 
B 2 11  VAL 11  11  11  VAL VAL B . n 
B 2 12  VAL 12  12  12  VAL VAL B . n 
B 2 13  GLN 13  13  13  GLN GLN B . n 
B 2 14  ASP 14  14  14  ASP ASP B . n 
B 2 15  PRO 15  15  15  PRO PRO B . n 
B 2 16  LEU 16  16  16  LEU LEU B . n 
B 2 17  LEU 17  17  17  LEU LEU B . n 
B 2 18  CYS 18  18  18  CYS CYS B . n 
B 2 19  ASP 19  19  19  ASP ASP B . n 
B 2 20  LEU 20  20  20  LEU LEU B . n 
B 2 21  PRO 21  21  21  PRO PRO B . n 
B 2 22  ILE 22  22  22  ILE ILE B . n 
B 2 23  GLN 23  23  23  GLN GLN B . n 
B 2 24  VAL 24  24  24  VAL VAL B . n 
B 2 25  THR 25  25  25  THR THR B . n 
B 2 26  LEU 26  26  26  LEU LEU B . n 
B 2 27  GLU 27  27  27  GLU GLU B . n 
B 2 28  GLU 28  28  28  GLU GLU B . n 
B 2 29  VAL 29  29  29  VAL VAL B . n 
B 2 30  ASN 30  30  30  ASN ASN B . n 
B 2 31  SER 31  31  31  SER SER B . n 
B 2 32  GLN 32  32  32  GLN GLN B . n 
B 2 33  ILE 33  33  33  ILE ILE B . n 
B 2 34  ALA 34  34  34  ALA ALA B . n 
B 2 35  LEU 35  35  35  LEU LEU B . n 
B 2 36  GLU 36  36  36  GLU GLU B . n 
B 2 37  TYR 37  37  37  TYR TYR B . n 
B 2 38  GLY 38  38  38  GLY GLY B . n 
B 2 39  GLN 39  39  39  GLN GLN B . n 
B 2 40  ALA 40  40  40  ALA ALA B . n 
B 2 41  MET 41  41  41  MET MET B . n 
B 2 42  THR 42  42  42  THR THR B . n 
B 2 43  VAL 43  43  43  VAL VAL B . n 
B 2 44  ARG 44  44  44  ARG ARG B . n 
B 2 45  VAL 45  45  45  VAL VAL B . n 
B 2 46  CYS 46  46  46  CYS CYS B . n 
B 2 47  LYS 47  47  47  LYS LYS B . n 
B 2 48  MET 48  48  48  MET MET B . n 
B 2 49  ASP 49  49  49  ASP ASP B . n 
B 2 50  GLY 50  50  50  GLY GLY B . n 
B 2 51  GLU 51  51  51  GLU GLU B . n 
B 2 52  VAL 52  52  52  VAL VAL B . n 
B 2 53  MET 53  53  53  MET MET B . n 
B 2 54  PRO 54  54  54  PRO PRO B . n 
B 2 55  VAL 55  55  55  VAL VAL B . n 
B 2 56  VAL 56  56  56  VAL VAL B . n 
B 2 57  VAL 57  57  57  VAL VAL B . n 
B 2 58  VAL 58  58  58  VAL VAL B . n 
B 2 59  GLN 59  59  59  GLN GLN B . n 
B 2 60  SER 60  60  60  SER SER B . n 
B 2 61  ALA 61  61  61  ALA ALA B . n 
B 2 62  THR 62  62  62  THR THR B . n 
B 2 63  VAL 63  63  63  VAL VAL B . n 
B 2 64  LEU 64  64  64  LEU LEU B . n 
B 2 65  ASP 65  65  65  ASP ASP B . n 
B 2 66  LEU 66  66  66  LEU LEU B . n 
B 2 67  LYS 67  67  67  LYS LYS B . n 
B 2 68  LYS 68  68  68  LYS LYS B . n 
B 2 69  ALA 69  69  69  ALA ALA B . n 
B 2 70  ILE 70  70  70  ILE ILE B . n 
B 2 71  GLN 71  71  71  GLN GLN B . n 
B 2 72  ARG 72  72  72  ARG ARG B . n 
B 2 73  TYR 73  73  73  TYR TYR B . n 
B 2 74  VAL 74  74  74  VAL VAL B . n 
B 2 75  GLN 75  75  75  GLN GLN B . n 
B 2 76  LEU 76  76  76  LEU LEU B . n 
B 2 77  LYS 77  77  77  LYS LYS B . n 
B 2 78  GLN 78  78  78  GLN GLN B . n 
B 2 79  GLU 79  79  79  GLU GLU B . n 
B 2 80  ARG 80  80  80  ARG ARG B . n 
B 2 81  GLU 81  81  81  GLU GLU B . n 
B 2 82  GLY 82  82  82  GLY GLY B . n 
B 2 83  GLY 83  83  83  GLY GLY B . n 
B 2 84  ILE 84  84  84  ILE ILE B . n 
B 2 85  GLN 85  85  85  GLN GLN B . n 
B 2 86  HIS 86  86  86  HIS HIS B . n 
B 2 87  ILE 87  87  87  ILE ILE B . n 
B 2 88  SER 88  88  88  SER SER B . n 
B 2 89  TRP 89  89  89  TRP TRP B . n 
B 2 90  SER 90  90  90  SER SER B . n 
B 2 91  TYR 91  91  91  TYR TYR B . n 
B 2 92  VAL 92  92  92  VAL VAL B . n 
B 2 93  TRP 93  93  93  TRP TRP B . n 
B 2 94  ARG 94  94  94  ARG ARG B . n 
B 2 95  THR 95  95  95  THR THR B . n 
B 2 96  TYR 96  96  96  TYR TYR B . n 
B 2 97  HIS 97  97  97  HIS HIS B . n 
B 2 98  LEU 98  98  98  LEU LEU B . n 
B 2 99  THR 99  99  99  THR THR B . n 
B 2 100 SER 100 100 100 SER SER B . n 
B 2 101 ALA 101 101 101 ALA ALA B . n 
B 2 102 GLY 102 102 102 GLY GLY B . n 
B 2 103 GLU 103 103 103 GLU GLU B . n 
B 2 104 LYS 104 104 104 LYS LYS B . n 
B 2 105 LEU 105 105 105 LEU LEU B . n 
B 2 106 THR 106 106 106 THR THR B . n 
B 2 107 GLU 107 107 107 GLU GLU B . n 
B 2 108 ASP 108 108 108 ASP ASP B . n 
B 2 109 ARG 109 109 109 ARG ARG B . n 
B 2 110 LYS 110 110 110 LYS LYS B . n 
B 2 111 LYS 111 111 111 LYS LYS B . n 
B 2 112 LEU 112 112 112 LEU LEU B . n 
B 2 113 ARG 113 113 113 ARG ARG B . n 
B 2 114 ASP 114 114 114 ASP ASP B . n 
B 2 115 TYR 115 115 115 TYR TYR B . n 
B 2 116 GLY 116 116 116 GLY GLY B . n 
B 2 117 ILE 117 117 117 ILE ILE B . n 
B 2 118 ARG 118 118 118 ARG ARG B . n 
B 2 119 ASN 119 119 119 ASN ASN B . n 
B 2 120 ARG 120 120 120 ARG ARG B . n 
B 2 121 ASP 121 121 121 ASP ASP B . n 
B 2 122 GLU 122 122 122 GLU GLU B . n 
B 2 123 VAL 123 123 123 VAL VAL B . n 
B 2 124 SER 124 124 124 SER SER B . n 
B 2 125 PHE 125 125 125 PHE PHE B . n 
B 2 126 ILE 126 126 126 ILE ILE B . n 
B 2 127 LYS 127 127 127 LYS LYS B . n 
B 2 128 LYS 128 128 128 LYS LYS B . n 
B 2 129 LEU 129 129 ?   ?   ?   B . n 
B 2 130 ARG 130 130 ?   ?   ?   B . n 
B 2 131 GLN 131 131 ?   ?   ?   B . n 
B 2 132 LYS 132 132 ?   ?   ?   B . n 
C 3 1   MET 1   1   ?   ?   ?   C . n 
C 3 2   ASN 2   2   ?   ?   ?   C . n 
C 3 3   ASP 3   3   ?   ?   ?   C . n 
C 3 4   TRP 4   4   ?   ?   ?   C . n 
C 3 5   MET 5   5   ?   ?   ?   C . n 
C 3 6   PRO 6   6   ?   ?   ?   C . n 
C 3 7   ILE 7   7   ?   ?   ?   C . n 
C 3 8   ALA 8   8   ?   ?   ?   C . n 
C 3 9   LYS 9   9   ?   ?   ?   C . n 
C 3 10  GLU 10  10  10  GLU GLU C . n 
C 3 11  TYR 11  11  11  TYR TYR C . n 
C 3 12  ASP 12  12  12  ASP ASP C . n 
C 3 13  PRO 13  13  13  PRO PRO C . n 
C 3 14  LEU 14  14  14  LEU LEU C . n 
C 3 15  LYS 15  15  15  LYS LYS C . n 
C 3 16  ALA 16  16  16  ALA ALA C . n 
C 3 17  GLY 17  17  17  GLY GLY C . n 
C 3 18  SER 18  18  18  SER SER C . n 
C 3 19  ILE 19  19  19  ILE ILE C . n 
C 3 20  ASP 20  20  20  ASP ASP C . n 
C 3 21  GLY 21  21  21  GLY GLY C . n 
C 3 22  THR 22  22  22  THR THR C . n 
C 3 23  ASP 23  23  23  ASP ASP C . n 
C 3 24  GLU 24  24  24  GLU GLU C . n 
C 3 25  ASP 25  25  25  ASP ASP C . n 
C 3 26  PRO 26  26  26  PRO PRO C . n 
C 3 27  HIS 27  27  27  HIS HIS C . n 
C 3 28  ASP 28  28  28  ASP ASP C . n 
C 3 29  ARG 29  29  29  ARG ARG C . n 
C 3 30  ALA 30  30  30  ALA ALA C . n 
C 3 31  VAL 31  31  31  VAL VAL C . n 
C 3 32  TRP 32  32  32  TRP TRP C . n 
C 3 33  ARG 33  33  33  ARG ARG C . n 
C 3 34  ALA 34  34  34  ALA ALA C . n 
C 3 35  MET 35  35  35  MET MET C . n 
C 3 36  LEU 36  36  36  LEU LEU C . n 
C 3 37  ALA 37  37  37  ALA ALA C . n 
C 3 38  ARG 38  38  38  ARG ARG C . n 
C 3 39  TYR 39  39  39  TYR TYR C . n 
C 3 40  VAL 40  40  40  VAL VAL C . n 
C 3 41  PRO 41  41  41  PRO PRO C . n 
C 3 42  ASN 42  42  42  ASN ASN C . n 
C 3 43  LYS 43  43  43  LYS LYS C . n 
C 3 44  GLY 44  44  44  GLY GLY C . n 
C 3 45  VAL 45  45  45  VAL VAL C . n 
C 3 46  ILE 46  46  46  ILE ILE C . n 
C 3 47  GLY 47  47  47  GLY GLY C . n 
C 3 48  ASP 48  48  48  ASP ASP C . n 
C 3 49  PRO 49  49  49  PRO PRO C . n 
C 3 50  LEU 50  50  50  LEU LEU C . n 
C 3 51  LEU 51  51  51  LEU LEU C . n 
C 3 52  THR 52  52  52  THR THR C . n 
C 3 53  LEU 53  53  53  LEU LEU C . n 
C 3 54  PHE 54  54  54  PHE PHE C . n 
C 3 55  VAL 55  55  55  VAL VAL C . n 
C 3 56  ALA 56  56  56  ALA ALA C . n 
C 3 57  ARG 57  57  57  ARG ARG C . n 
C 3 58  LEU 58  58  58  LEU LEU C . n 
C 3 59  ASN 59  59  59  ASN ASN C . n 
C 3 60  LEU 60  60  60  LEU LEU C . n 
C 3 61  GLN 61  61  61  GLN GLN C . n 
C 3 62  THR 62  62  62  THR THR C . n 
C 3 63  LYS 63  63  63  LYS LYS C . n 
C 3 64  GLU 64  64  64  GLU GLU C . n 
C 3 65  ASP 65  65  65  ASP ASP C . n 
C 3 66  LYS 66  66  66  LYS LYS C . n 
C 3 67  LEU 67  67  67  LEU LEU C . n 
C 3 68  LYS 68  68  68  LYS LYS C . n 
C 3 69  GLU 69  69  69  GLU GLU C . n 
C 3 70  VAL 70  70  70  VAL VAL C . n 
C 3 71  PHE 71  71  71  PHE PHE C . n 
C 3 72  SER 72  72  72  SER SER C . n 
C 3 73  ARG 73  73  73  ARG ARG C . n 
C 3 74  TYR 74  74  74  TYR TYR C . n 
C 3 75  GLY 75  75  75  GLY GLY C . n 
C 3 76  ASP 76  76  76  ASP ASP C . n 
C 3 77  ILE 77  77  77  ILE ILE C . n 
C 3 78  ARG 78  78  78  ARG ARG C . n 
C 3 79  ARG 79  79  79  ARG ARG C . n 
C 3 80  LEU 80  80  80  LEU LEU C . n 
C 3 81  ARG 81  81  81  ARG ARG C . n 
C 3 82  LEU 82  82  82  LEU LEU C . n 
C 3 83  VAL 83  83  83  VAL VAL C . n 
C 3 84  ARG 84  84  84  ARG ARG C . n 
C 3 85  ASP 85  85  85  ASP ASP C . n 
C 3 86  LEU 86  86  86  LEU LEU C . n 
C 3 87  VAL 87  87  87  VAL VAL C . n 
C 3 88  THR 88  88  88  THR THR C . n 
C 3 89  GLY 89  89  89  GLY GLY C . n 
C 3 90  PHE 90  90  90  PHE PHE C . n 
C 3 91  SER 91  91  91  SER SER C . n 
C 3 92  LYS 92  92  92  LYS LYS C . n 
C 3 93  GLY 93  93  93  GLY GLY C . n 
C 3 94  TYR 94  94  94  TYR TYR C . n 
C 3 95  ALA 95  95  95  ALA ALA C . n 
C 3 96  PHE 96  96  96  PHE PHE C . n 
C 3 97  ILE 97  97  97  ILE ILE C . n 
C 3 98  GLU 98  98  98  GLU GLU C . n 
C 3 99  TYR 99  99  99  TYR TYR C . n 
C 3 100 LYS 100 100 100 LYS LYS C . n 
C 3 101 GLU 101 101 101 GLU GLU C . n 
C 3 102 GLU 102 102 102 GLU GLU C . n 
C 3 103 ARG 103 103 103 ARG ARG C . n 
C 3 104 ALA 104 104 104 ALA ALA C . n 
C 3 105 VAL 105 105 105 VAL VAL C . n 
C 3 106 ILE 106 106 106 ILE ILE C . n 
C 3 107 LYS 107 107 107 LYS LYS C . n 
C 3 108 ALA 108 108 108 ALA ALA C . n 
C 3 109 TYR 109 109 109 TYR TYR C . n 
C 3 110 ARG 110 110 110 ARG ARG C . n 
C 3 111 ASP 111 111 111 ASP ASP C . n 
C 3 112 ALA 112 112 112 ALA ALA C . n 
C 3 113 ASP 113 113 113 ASP ASP C . n 
C 3 114 GLY 114 114 114 GLY GLY C . n 
C 3 115 LEU 115 115 115 LEU LEU C . n 
C 3 116 VAL 116 116 116 VAL VAL C . n 
C 3 117 ILE 117 117 117 ILE ILE C . n 
C 3 118 ASP 118 118 118 ASP ASP C . n 
C 3 119 GLN 119 119 119 GLN GLN C . n 
C 3 120 HIS 120 120 120 HIS HIS C . n 
C 3 121 GLU 121 121 121 GLU GLU C . n 
C 3 122 ILE 122 122 122 ILE ILE C . n 
C 3 123 PHE 123 123 123 PHE PHE C . n 
C 3 124 VAL 124 124 124 VAL VAL C . n 
C 3 125 ASP 125 125 125 ASP ASP C . n 
C 3 126 TYR 126 126 126 TYR TYR C . n 
C 3 127 GLU 127 127 127 GLU GLU C . n 
C 3 128 LEU 128 128 128 LEU LEU C . n 
C 3 129 GLU 129 129 129 GLU GLU C . n 
C 3 130 ARG 130 130 130 ARG ARG C . n 
C 3 131 THR 131 131 131 THR THR C . n 
C 3 132 LEU 132 132 132 LEU LEU C . n 
C 3 133 LYS 133 133 133 LYS LYS C . n 
C 3 134 GLY 134 134 134 GLY GLY C . n 
C 3 135 TRP 135 135 135 TRP TRP C . n 
C 3 136 ILE 136 136 136 ILE ILE C . n 
C 3 137 PRO 137 137 137 PRO PRO C . n 
C 3 138 ARG 138 138 138 ARG ARG C . n 
C 3 139 ARG 139 139 139 ARG ARG C . n 
C 3 140 LEU 140 140 140 LEU LEU C . n 
C 3 141 GLY 141 141 141 GLY GLY C . n 
C 3 142 GLY 142 142 142 GLY GLY C . n 
C 3 143 GLY 143 143 143 GLY GLY C . n 
C 3 144 LEU 144 144 144 LEU LEU C . n 
C 3 145 GLY 145 145 145 GLY GLY C . n 
C 3 146 GLY 146 146 146 GLY GLY C . n 
C 3 147 LYS 147 147 147 LYS LYS C . n 
C 3 148 LYS 148 148 148 LYS LYS C . n 
C 3 149 GLU 149 149 149 GLU GLU C . n 
C 3 150 SER 150 150 150 SER SER C . n 
C 3 151 GLY 151 151 151 GLY GLY C . n 
C 3 152 GLN 152 152 152 GLN GLN C . n 
C 3 153 LEU 153 153 153 LEU LEU C . n 
C 3 154 ARG 154 154 154 ARG ARG C . n 
C 3 155 PHE 155 155 155 PHE PHE C . n 
C 3 156 GLY 156 156 156 GLY GLY C . n 
C 3 157 GLY 157 157 157 GLY GLY C . n 
C 3 158 ARG 158 158 158 ARG ARG C . n 
C 3 159 ASP 159 159 159 ASP ASP C . n 
C 3 160 ARG 160 160 160 ARG ARG C . n 
C 3 161 PRO 161 161 161 PRO PRO C . n 
C 3 162 PHE 162 162 162 PHE PHE C . n 
C 3 163 ARG 163 163 163 ARG ARG C . n 
C 3 164 LYS 164 164 164 LYS LYS C . n 
C 3 165 PRO 165 165 ?   ?   ?   C . n 
C 3 166 ILE 166 166 ?   ?   ?   C . n 
C 3 167 ASN 167 167 ?   ?   ?   C . n 
C 3 168 LEU 168 168 ?   ?   ?   C . n 
C 3 169 PRO 169 169 ?   ?   ?   C . n 
C 3 170 VAL 170 170 ?   ?   ?   C . n 
C 3 171 VAL 171 171 ?   ?   ?   C . n 
C 3 172 LYS 172 172 ?   ?   ?   C . n 
C 3 173 ASN 173 173 ?   ?   ?   C . n 
C 3 174 ASP 174 174 ?   ?   ?   C . n 
C 3 175 LEU 175 175 ?   ?   ?   C . n 
C 3 176 TYR 176 176 ?   ?   ?   C . n 
C 3 177 ARG 177 177 ?   ?   ?   C . n 
C 3 178 GLU 178 178 ?   ?   ?   C . n 
C 3 179 GLY 179 179 ?   ?   ?   C . n 
C 3 180 LYS 180 180 ?   ?   ?   C . n 
C 3 181 ARG 181 181 ?   ?   ?   C . n 
C 3 182 GLU 182 182 ?   ?   ?   C . n 
C 3 183 ARG 183 183 ?   ?   ?   C . n 
C 3 184 ARG 184 184 ?   ?   ?   C . n 
C 3 185 GLU 185 185 ?   ?   ?   C . n 
C 3 186 ARG 186 186 ?   ?   ?   C . n 
C 3 187 SER 187 187 ?   ?   ?   C . n 
C 3 188 ARG 188 188 ?   ?   ?   C . n 
C 3 189 SER 189 189 ?   ?   ?   C . n 
C 3 190 ARG 190 190 ?   ?   ?   C . n 
C 3 191 GLU 191 191 ?   ?   ?   C . n 
C 3 192 ARG 192 192 ?   ?   ?   C . n 
C 3 193 HIS 193 193 ?   ?   ?   C . n 
C 3 194 TRP 194 194 ?   ?   ?   C . n 
C 3 195 ASP 195 195 ?   ?   ?   C . n 
C 3 196 SER 196 196 ?   ?   ?   C . n 
C 3 197 ARG 197 197 ?   ?   ?   C . n 
C 3 198 THR 198 198 ?   ?   ?   C . n 
C 3 199 ARG 199 199 ?   ?   ?   C . n 
C 3 200 ASP 200 200 ?   ?   ?   C . n 
C 3 201 ARG 201 201 ?   ?   ?   C . n 
C 3 202 ASP 202 202 ?   ?   ?   C . n 
C 3 203 HIS 203 203 ?   ?   ?   C . n 
C 3 204 ASP 204 204 ?   ?   ?   C . n 
C 3 205 ARG 205 205 ?   ?   ?   C . n 
C 3 206 GLY 206 206 ?   ?   ?   C . n 
C 3 207 ARG 207 207 ?   ?   ?   C . n 
C 3 208 GLU 208 208 ?   ?   ?   C . n 
C 3 209 LYS 209 209 ?   ?   ?   C . n 
C 3 210 ARG 210 210 ?   ?   ?   C . n 
C 3 211 TRP 211 211 ?   ?   ?   C . n 
C 3 212 GLN 212 212 ?   ?   ?   C . n 
C 3 213 GLU 213 213 ?   ?   ?   C . n 
C 3 214 ARG 214 214 ?   ?   ?   C . n 
C 3 215 GLU 215 215 ?   ?   ?   C . n 
C 3 216 PRO 216 216 ?   ?   ?   C . n 
C 3 217 THR 217 217 ?   ?   ?   C . n 
C 3 218 ARG 218 218 ?   ?   ?   C . n 
C 3 219 VAL 219 219 ?   ?   ?   C . n 
C 3 220 TRP 220 220 ?   ?   ?   C . n 
C 3 221 PRO 221 221 ?   ?   ?   C . n 
C 3 222 ASP 222 222 ?   ?   ?   C . n 
C 3 223 ASN 223 223 ?   ?   ?   C . n 
C 3 224 ASP 224 224 ?   ?   ?   C . n 
C 3 225 TRP 225 225 ?   ?   ?   C . n 
C 3 226 GLU 226 226 ?   ?   ?   C . n 
C 3 227 ARG 227 227 ?   ?   ?   C . n 
C 3 228 GLU 228 228 ?   ?   ?   C . n 
C 3 229 ARG 229 229 ?   ?   ?   C . n 
C 3 230 ASP 230 230 ?   ?   ?   C . n 
C 3 231 PHE 231 231 ?   ?   ?   C . n 
C 3 232 ARG 232 232 ?   ?   ?   C . n 
C 3 233 ASP 233 233 ?   ?   ?   C . n 
C 3 234 ASP 234 234 ?   ?   ?   C . n 
C 3 235 ARG 235 235 ?   ?   ?   C . n 
C 3 236 ILE 236 236 ?   ?   ?   C . n 
C 3 237 LYS 237 237 ?   ?   ?   C . n 
C 3 238 GLY 238 238 ?   ?   ?   C . n 
C 3 239 ARG 239 239 ?   ?   ?   C . n 
C 3 240 GLU 240 240 ?   ?   ?   C . n 
C 3 241 LYS 241 241 ?   ?   ?   C . n 
C 3 242 LYS 242 242 ?   ?   ?   C . n 
C 3 243 GLU 243 243 ?   ?   ?   C . n 
C 3 244 ARG 244 244 ?   ?   ?   C . n 
C 3 245 GLY 245 245 ?   ?   ?   C . n 
C 3 246 LYS 246 246 ?   ?   ?   C . n 
D 4 1   MET 1   1   ?   ?   ?   D . n 
D 4 2   ALA 2   2   ?   ?   ?   D . n 
D 4 3   LEU 3   3   ?   ?   ?   D . n 
D 4 4   PRO 4   4   ?   ?   ?   D . n 
D 4 5   PRO 5   5   ?   ?   ?   D . n 
D 4 6   PHE 6   6   ?   ?   ?   D . n 
D 4 7   PHE 7   7   ?   ?   ?   D . n 
D 4 8   GLY 8   8   ?   ?   ?   D . n 
D 4 9   GLN 9   9   ?   ?   ?   D . n 
D 4 10  GLY 10  10  ?   ?   ?   D . n 
D 4 11  ARG 11  11  ?   ?   ?   D . n 
D 4 12  PRO 12  12  ?   ?   ?   D . n 
D 4 13  GLY 13  13  ?   ?   ?   D . n 
D 4 14  PRO 14  14  ?   ?   ?   D . n 
D 4 15  PRO 15  15  ?   ?   ?   D . n 
D 4 16  PRO 16  16  ?   ?   ?   D . n 
D 4 17  PRO 17  17  ?   ?   ?   D . n 
D 4 18  GLN 18  18  ?   ?   ?   D . n 
D 4 19  PRO 19  19  ?   ?   ?   D . n 
D 4 20  PRO 20  20  ?   ?   ?   D . n 
D 4 21  PRO 21  21  ?   ?   ?   D . n 
D 4 22  PRO 22  22  ?   ?   ?   D . n 
D 4 23  ALA 23  23  ?   ?   ?   D . n 
D 4 24  PRO 24  24  ?   ?   ?   D . n 
D 4 25  PHE 25  25  ?   ?   ?   D . n 
D 4 26  GLY 26  26  ?   ?   ?   D . n 
D 4 27  CYS 27  27  ?   ?   ?   D . n 
D 4 28  PRO 28  28  ?   ?   ?   D . n 
D 4 29  PRO 29  29  ?   ?   ?   D . n 
D 4 30  PRO 30  30  ?   ?   ?   D . n 
D 4 31  PRO 31  31  ?   ?   ?   D . n 
D 4 32  LEU 32  32  ?   ?   ?   D . n 
D 4 33  PRO 33  33  ?   ?   ?   D . n 
D 4 34  SER 34  34  ?   ?   ?   D . n 
D 4 35  PRO 35  35  ?   ?   ?   D . n 
D 4 36  ALA 36  36  ?   ?   ?   D . n 
D 4 37  PHE 37  37  ?   ?   ?   D . n 
D 4 38  PRO 38  38  ?   ?   ?   D . n 
D 4 39  PRO 39  39  ?   ?   ?   D . n 
D 4 40  PRO 40  40  ?   ?   ?   D . n 
D 4 41  LEU 41  41  ?   ?   ?   D . n 
D 4 42  PRO 42  42  ?   ?   ?   D . n 
D 4 43  GLN 43  43  ?   ?   ?   D . n 
D 4 44  ARG 44  44  ?   ?   ?   D . n 
D 4 45  PRO 45  45  ?   ?   ?   D . n 
D 4 46  GLY 46  46  ?   ?   ?   D . n 
D 4 47  PRO 47  47  ?   ?   ?   D . n 
D 4 48  PHE 48  48  ?   ?   ?   D . n 
D 4 49  PRO 49  49  ?   ?   ?   D . n 
D 4 50  GLY 50  50  ?   ?   ?   D . n 
D 4 51  ALA 51  51  ?   ?   ?   D . n 
D 4 52  SER 52  52  ?   ?   ?   D . n 
D 4 53  ALA 53  53  ?   ?   ?   D . n 
D 4 54  PRO 54  54  ?   ?   ?   D . n 
D 4 55  PHE 55  55  ?   ?   ?   D . n 
D 4 56  LEU 56  56  ?   ?   ?   D . n 
D 4 57  GLN 57  57  ?   ?   ?   D . n 
D 4 58  PRO 58  58  ?   ?   ?   D . n 
D 4 59  PRO 59  59  ?   ?   ?   D . n 
D 4 60  LEU 60  60  ?   ?   ?   D . n 
D 4 61  ALA 61  61  ?   ?   ?   D . n 
D 4 62  LEU 62  62  ?   ?   ?   D . n 
D 4 63  GLN 63  63  ?   ?   ?   D . n 
D 4 64  PRO 64  64  ?   ?   ?   D . n 
D 4 65  ARG 65  65  ?   ?   ?   D . n 
D 4 66  ALA 66  66  ?   ?   ?   D . n 
D 4 67  SER 67  67  ?   ?   ?   D . n 
D 4 68  ALA 68  68  ?   ?   ?   D . n 
D 4 69  GLU 69  69  ?   ?   ?   D . n 
D 4 70  ALA 70  70  ?   ?   ?   D . n 
D 4 71  SER 71  71  ?   ?   ?   D . n 
D 4 72  ARG 72  72  ?   ?   ?   D . n 
D 4 73  GLY 73  73  ?   ?   ?   D . n 
D 4 74  GLY 74  74  ?   ?   ?   D . n 
D 4 75  GLY 75  75  ?   ?   ?   D . n 
D 4 76  GLY 76  76  ?   ?   ?   D . n 
D 4 77  ALA 77  77  ?   ?   ?   D . n 
D 4 78  GLY 78  78  ?   ?   ?   D . n 
D 4 79  ALA 79  79  ?   ?   ?   D . n 
D 4 80  PHE 80  80  ?   ?   ?   D . n 
D 4 81  TYR 81  81  ?   ?   ?   D . n 
D 4 82  PRO 82  82  ?   ?   ?   D . n 
D 4 83  VAL 83  83  ?   ?   ?   D . n 
D 4 84  PRO 84  84  ?   ?   ?   D . n 
D 4 85  PRO 85  85  ?   ?   ?   D . n 
D 4 86  PRO 86  86  ?   ?   ?   D . n 
D 4 87  PRO 87  87  ?   ?   ?   D . n 
D 4 88  LEU 88  88  ?   ?   ?   D . n 
D 4 89  PRO 89  89  ?   ?   ?   D . n 
D 4 90  PRO 90  90  ?   ?   ?   D . n 
D 4 91  PRO 91  91  ?   ?   ?   D . n 
D 4 92  PRO 92  92  ?   ?   ?   D . n 
D 4 93  PRO 93  93  ?   ?   ?   D . n 
D 4 94  GLN 94  94  ?   ?   ?   D . n 
D 4 95  CYS 95  95  ?   ?   ?   D . n 
D 4 96  ARG 96  96  ?   ?   ?   D . n 
D 4 97  PRO 97  97  ?   ?   ?   D . n 
D 4 98  PHE 98  98  ?   ?   ?   D . n 
D 4 99  PRO 99  99  ?   ?   ?   D . n 
D 4 100 GLY 100 100 ?   ?   ?   D . n 
D 4 101 THR 101 101 ?   ?   ?   D . n 
D 4 102 ASP 102 102 ?   ?   ?   D . n 
D 4 103 ALA 103 103 ?   ?   ?   D . n 
D 4 104 GLY 104 104 ?   ?   ?   D . n 
D 4 105 GLU 105 105 ?   ?   ?   D . n 
D 4 106 ARG 106 106 ?   ?   ?   D . n 
D 4 107 PRO 107 107 ?   ?   ?   D . n 
D 4 108 ARG 108 108 ?   ?   ?   D . n 
D 4 109 PRO 109 109 ?   ?   ?   D . n 
D 4 110 PRO 110 110 ?   ?   ?   D . n 
D 4 111 PRO 111 111 ?   ?   ?   D . n 
D 4 112 PRO 112 112 ?   ?   ?   D . n 
D 4 113 GLY 113 113 ?   ?   ?   D . n 
D 4 114 PRO 114 114 ?   ?   ?   D . n 
D 4 115 GLY 115 115 ?   ?   ?   D . n 
D 4 116 PRO 116 116 ?   ?   ?   D . n 
D 4 117 PRO 117 117 ?   ?   ?   D . n 
D 4 118 TRP 118 118 ?   ?   ?   D . n 
D 4 119 SER 119 119 ?   ?   ?   D . n 
D 4 120 PRO 120 120 ?   ?   ?   D . n 
D 4 121 ARG 121 121 ?   ?   ?   D . n 
D 4 122 TRP 122 122 ?   ?   ?   D . n 
D 4 123 PRO 123 123 ?   ?   ?   D . n 
D 4 124 GLU 124 124 ?   ?   ?   D . n 
D 4 125 ALA 125 125 ?   ?   ?   D . n 
D 4 126 PRO 126 126 ?   ?   ?   D . n 
D 4 127 PRO 127 127 ?   ?   ?   D . n 
D 4 128 PRO 128 128 ?   ?   ?   D . n 
D 4 129 PRO 129 129 ?   ?   ?   D . n 
D 4 130 ALA 130 130 ?   ?   ?   D . n 
D 4 131 ASP 131 131 ?   ?   ?   D . n 
D 4 132 VAL 132 132 ?   ?   ?   D . n 
D 4 133 LEU 133 133 ?   ?   ?   D . n 
D 4 134 GLY 134 134 ?   ?   ?   D . n 
D 4 135 ASP 135 135 ?   ?   ?   D . n 
D 4 136 ALA 136 136 ?   ?   ?   D . n 
D 4 137 ALA 137 137 ?   ?   ?   D . n 
D 4 138 LEU 138 138 ?   ?   ?   D . n 
D 4 139 GLN 139 139 ?   ?   ?   D . n 
D 4 140 ARG 140 140 ?   ?   ?   D . n 
D 4 141 LEU 141 141 ?   ?   ?   D . n 
D 4 142 ARG 142 142 ?   ?   ?   D . n 
D 4 143 ASP 143 143 ?   ?   ?   D . n 
D 4 144 ARG 144 144 ?   ?   ?   D . n 
D 4 145 GLN 145 145 ?   ?   ?   D . n 
D 4 146 TRP 146 146 ?   ?   ?   D . n 
D 4 147 LEU 147 147 ?   ?   ?   D . n 
D 4 148 GLU 148 148 ?   ?   ?   D . n 
D 4 149 ALA 149 149 ?   ?   ?   D . n 
D 4 150 VAL 150 150 ?   ?   ?   D . n 
D 4 151 PHE 151 151 ?   ?   ?   D . n 
D 4 152 GLY 152 152 ?   ?   ?   D . n 
D 4 153 THR 153 153 ?   ?   ?   D . n 
D 4 154 PRO 154 154 ?   ?   ?   D . n 
D 4 155 ARG 155 155 ?   ?   ?   D . n 
D 4 156 ARG 156 156 ?   ?   ?   D . n 
D 4 157 ALA 157 157 ?   ?   ?   D . n 
D 4 158 GLY 158 158 ?   ?   ?   D . n 
D 4 159 CYS 159 159 ?   ?   ?   D . n 
D 4 160 PRO 160 160 ?   ?   ?   D . n 
D 4 161 VAL 161 161 ?   ?   ?   D . n 
D 4 162 PRO 162 162 ?   ?   ?   D . n 
D 4 163 GLN 163 163 ?   ?   ?   D . n 
D 4 164 ARG 164 164 ?   ?   ?   D . n 
D 4 165 THR 165 165 ?   ?   ?   D . n 
D 4 166 HIS 166 166 ?   ?   ?   D . n 
D 4 167 ALA 167 167 ?   ?   ?   D . n 
D 4 168 GLY 168 168 ?   ?   ?   D . n 
D 4 169 PRO 169 169 ?   ?   ?   D . n 
D 4 170 SER 170 170 ?   ?   ?   D . n 
D 4 171 LEU 171 171 ?   ?   ?   D . n 
D 4 172 GLY 172 172 ?   ?   ?   D . n 
D 4 173 GLU 173 173 ?   ?   ?   D . n 
D 4 174 VAL 174 174 ?   ?   ?   D . n 
D 4 175 ARG 175 175 ?   ?   ?   D . n 
D 4 176 ALA 176 176 ?   ?   ?   D . n 
D 4 177 ARG 177 177 ?   ?   ?   D . n 
D 4 178 LEU 178 178 ?   ?   ?   D . n 
D 4 179 LEU 179 179 ?   ?   ?   D . n 
D 4 180 ARG 180 180 ?   ?   ?   D . n 
D 4 181 ALA 181 181 ?   ?   ?   D . n 
D 4 182 LEU 182 182 ?   ?   ?   D . n 
D 4 183 ARG 183 183 ?   ?   ?   D . n 
D 4 184 LEU 184 184 ?   ?   ?   D . n 
D 4 185 VAL 185 185 ?   ?   ?   D . n 
D 4 186 ARG 186 186 ?   ?   ?   D . n 
D 4 187 ARG 187 187 ?   ?   ?   D . n 
D 4 188 LEU 188 188 ?   ?   ?   D . n 
D 4 189 ARG 189 189 ?   ?   ?   D . n 
D 4 190 GLY 190 190 ?   ?   ?   D . n 
D 4 191 LEU 191 191 ?   ?   ?   D . n 
D 4 192 SER 192 192 ?   ?   ?   D . n 
D 4 193 GLN 193 193 ?   ?   ?   D . n 
D 4 194 ALA 194 194 ?   ?   ?   D . n 
D 4 195 LEU 195 195 ?   ?   ?   D . n 
D 4 196 ARG 196 196 ?   ?   ?   D . n 
D 4 197 GLU 197 197 ?   ?   ?   D . n 
D 4 198 ALA 198 198 ?   ?   ?   D . n 
D 4 199 GLU 199 199 ?   ?   ?   D . n 
D 4 200 ALA 200 200 ?   ?   ?   D . n 
D 4 201 ASP 201 201 ?   ?   ?   D . n 
D 4 202 GLY 202 202 ?   ?   ?   D . n 
D 4 203 ALA 203 203 ?   ?   ?   D . n 
D 4 204 ALA 204 204 ?   ?   ?   D . n 
D 4 205 TRP 205 205 ?   ?   ?   D . n 
D 4 206 VAL 206 206 ?   ?   ?   D . n 
D 4 207 LEU 207 207 ?   ?   ?   D . n 
D 4 208 LEU 208 208 ?   ?   ?   D . n 
D 4 209 TYR 209 209 ?   ?   ?   D . n 
D 4 210 SER 210 210 ?   ?   ?   D . n 
D 4 211 GLN 211 211 ?   ?   ?   D . n 
D 4 212 THR 212 212 ?   ?   ?   D . n 
D 4 213 ALA 213 213 ?   ?   ?   D . n 
D 4 214 PRO 214 214 ?   ?   ?   D . n 
D 4 215 LEU 215 215 ?   ?   ?   D . n 
D 4 216 ARG 216 216 ?   ?   ?   D . n 
D 4 217 ALA 217 217 ?   ?   ?   D . n 
D 4 218 GLU 218 218 ?   ?   ?   D . n 
D 4 219 LEU 219 219 ?   ?   ?   D . n 
D 4 220 ALA 220 220 ?   ?   ?   D . n 
D 4 221 GLU 221 221 ?   ?   ?   D . n 
D 4 222 ARG 222 222 ?   ?   ?   D . n 
D 4 223 LEU 223 223 ?   ?   ?   D . n 
D 4 224 GLN 224 224 ?   ?   ?   D . n 
D 4 225 PRO 225 225 ?   ?   ?   D . n 
D 4 226 LEU 226 226 ?   ?   ?   D . n 
D 4 227 THR 227 227 ?   ?   ?   D . n 
D 4 228 GLN 228 228 ?   ?   ?   D . n 
D 4 229 ALA 229 229 ?   ?   ?   D . n 
D 4 230 ALA 230 230 ?   ?   ?   D . n 
D 4 231 TYR 231 231 ?   ?   ?   D . n 
D 4 232 VAL 232 232 ?   ?   ?   D . n 
D 4 233 GLY 233 233 ?   ?   ?   D . n 
D 4 234 GLU 234 234 ?   ?   ?   D . n 
D 4 235 ALA 235 235 ?   ?   ?   D . n 
D 4 236 ARG 236 236 ?   ?   ?   D . n 
D 4 237 ARG 237 237 ?   ?   ?   D . n 
D 4 238 ARG 238 238 ?   ?   ?   D . n 
D 4 239 LEU 239 239 ?   ?   ?   D . n 
D 4 240 GLU 240 240 ?   ?   ?   D . n 
D 4 241 ARG 241 241 ?   ?   ?   D . n 
D 4 242 VAL 242 242 ?   ?   ?   D . n 
D 4 243 ARG 243 243 ?   ?   ?   D . n 
D 4 244 ARG 244 244 ?   ?   ?   D . n 
D 4 245 ARG 245 245 ?   ?   ?   D . n 
D 4 246 ARG 246 246 ?   ?   ?   D . n 
D 4 247 LEU 247 247 ?   ?   ?   D . n 
D 4 248 ARG 248 248 ?   ?   ?   D . n 
D 4 249 LEU 249 249 ?   ?   ?   D . n 
D 4 250 ARG 250 250 ?   ?   ?   D . n 
D 4 251 GLU 251 251 ?   ?   ?   D . n 
D 4 252 ARG 252 252 ?   ?   ?   D . n 
D 4 253 ALA 253 253 ?   ?   ?   D . n 
D 4 254 ARG 254 254 ?   ?   ?   D . n 
D 4 255 GLU 255 255 ?   ?   ?   D . n 
D 4 256 ARG 256 256 ?   ?   ?   D . n 
D 4 257 GLU 257 257 ?   ?   ?   D . n 
D 4 258 ALA 258 258 ?   ?   ?   D . n 
D 4 259 GLU 259 259 ?   ?   ?   D . n 
D 4 260 ARG 260 260 ?   ?   ?   D . n 
D 4 261 GLU 261 261 ?   ?   ?   D . n 
D 4 262 ALA 262 262 ?   ?   ?   D . n 
D 4 263 GLU 263 263 ?   ?   ?   D . n 
D 4 264 ALA 264 264 ?   ?   ?   D . n 
D 4 265 ALA 265 265 ?   ?   ?   D . n 
D 4 266 ARG 266 266 ?   ?   ?   D . n 
D 4 267 ALA 267 267 ?   ?   ?   D . n 
D 4 268 VAL 268 268 ?   ?   ?   D . n 
D 4 269 GLU 269 269 ?   ?   ?   D . n 
D 4 270 ARG 270 270 ?   ?   ?   D . n 
D 4 271 GLU 271 271 ?   ?   ?   D . n 
D 4 272 GLN 272 272 ?   ?   ?   D . n 
D 4 273 GLU 273 273 ?   ?   ?   D . n 
D 4 274 ILE 274 274 ?   ?   ?   D . n 
D 4 275 ASP 275 275 ?   ?   ?   D . n 
D 4 276 ARG 276 276 ?   ?   ?   D . n 
D 4 277 TRP 277 277 ?   ?   ?   D . n 
D 4 278 ARG 278 278 ?   ?   ?   D . n 
D 4 279 VAL 279 279 ?   ?   ?   D . n 
D 4 280 LYS 280 280 ?   ?   ?   D . n 
D 4 281 CYS 281 281 ?   ?   ?   D . n 
D 4 282 VAL 282 282 ?   ?   ?   D . n 
D 4 283 GLN 283 283 ?   ?   ?   D . n 
D 4 284 GLU 284 284 ?   ?   ?   D . n 
D 4 285 VAL 285 285 ?   ?   ?   D . n 
D 4 286 GLU 286 286 ?   ?   ?   D . n 
D 4 287 GLU 287 287 ?   ?   ?   D . n 
D 4 288 LYS 288 288 ?   ?   ?   D . n 
D 4 289 LYS 289 289 ?   ?   ?   D . n 
D 4 290 ARG 290 290 ?   ?   ?   D . n 
D 4 291 GLU 291 291 291 GLU GLU D . n 
D 4 292 GLN 292 292 292 GLN GLN D . n 
D 4 293 GLU 293 293 293 GLU GLU D . n 
D 4 294 LEU 294 294 294 LEU LEU D . n 
D 4 295 LYS 295 295 295 LYS LYS D . n 
D 4 296 ALA 296 296 296 ALA ALA D . n 
D 4 297 ALA 297 297 297 ALA ALA D . n 
D 4 298 ALA 298 298 298 ALA ALA D . n 
D 4 299 ASP 299 299 299 ASP ASP D . n 
D 4 300 GLY 300 300 300 GLY GLY D . n 
D 4 301 VAL 301 301 301 VAL VAL D . n 
D 4 302 LEU 302 302 302 LEU LEU D . n 
D 4 303 SER 303 303 303 SER SER D . n 
D 4 304 GLU 304 304 304 GLU GLU D . n 
D 4 305 VAL 305 305 305 VAL VAL D . n 
D 4 306 ARG 306 306 306 ARG ARG D . n 
D 4 307 LYS 307 307 307 LYS LYS D . n 
D 4 308 LYS 308 308 308 LYS LYS D . n 
D 4 309 GLN 309 309 309 GLN GLN D . n 
D 4 310 ALA 310 310 310 ALA ALA D . n 
D 4 311 ASP 311 311 311 ASP ASP D . n 
D 4 312 THR 312 312 312 THR THR D . n 
D 4 313 LYS 313 313 313 LYS LYS D . n 
D 4 314 ARG 314 314 314 ARG ARG D . n 
D 4 315 MET 315 315 315 MET MET D . n 
D 4 316 VAL 316 316 316 VAL VAL D . n 
D 4 317 ASP 317 317 317 ASP ASP D . n 
D 4 318 ILE 318 318 318 ILE ILE D . n 
D 4 319 LEU 319 319 319 LEU LEU D . n 
D 4 320 ARG 320 320 320 ARG ARG D . n 
D 4 321 ALA 321 321 321 ALA ALA D . n 
D 4 322 LEU 322 322 322 LEU LEU D . n 
D 4 323 GLU 323 323 323 GLU GLU D . n 
D 4 324 LYS 324 324 324 LYS LYS D . n 
D 4 325 LEU 325 325 325 LEU LEU D . n 
D 4 326 ARG 326 326 326 ARG ARG D . n 
D 4 327 LYS 327 327 327 LYS LYS D . n 
D 4 328 LEU 328 328 328 LEU LEU D . n 
D 4 329 ARG 329 329 329 ARG ARG D . n 
D 4 330 LYS 330 330 330 LYS LYS D . n 
D 4 331 GLU 331 331 331 GLU GLU D . n 
D 4 332 ALA 332 332 332 ALA ALA D . n 
D 4 333 ALA 333 333 333 ALA ALA D . n 
D 4 334 ALA 334 334 334 ALA ALA D . n 
D 4 335 ARG 335 335 335 ARG ARG D . n 
D 4 336 LYS 336 336 336 LYS LYS D . n 
D 4 337 GLY 337 337 337 GLY GLY D . n 
D 4 338 VAL 338 338 338 VAL VAL D . n 
D 4 339 CYS 339 339 339 CYS CYS D . n 
D 4 340 PRO 340 340 340 PRO PRO D . n 
D 4 341 PRO 341 341 341 PRO PRO D . n 
D 4 342 ALA 342 342 342 ALA ALA D . n 
D 4 343 SER 343 343 343 SER SER D . n 
D 4 344 ALA 344 344 344 ALA ALA D . n 
D 4 345 ASP 345 345 345 ASP ASP D . n 
D 4 346 GLU 346 346 346 GLU GLU D . n 
D 4 347 THR 347 347 347 THR THR D . n 
D 4 348 PHE 348 348 348 PHE PHE D . n 
D 4 349 THR 349 349 349 THR THR D . n 
D 4 350 HIS 350 350 350 HIS HIS D . n 
D 4 351 HIS 351 351 351 HIS HIS D . n 
D 4 352 LEU 352 352 352 LEU LEU D . n 
D 4 353 GLN 353 353 353 GLN GLN D . n 
D 4 354 ARG 354 354 354 ARG ARG D . n 
D 4 355 LEU 355 355 355 LEU LEU D . n 
D 4 356 ARG 356 356 356 ARG ARG D . n 
D 4 357 LYS 357 357 357 LYS LYS D . n 
D 4 358 LEU 358 358 358 LEU LEU D . n 
D 4 359 ILE 359 359 359 ILE ILE D . n 
D 4 360 LYS 360 360 360 LYS LYS D . n 
D 4 361 LYS 361 361 361 LYS LYS D . n 
D 4 362 ARG 362 362 362 ARG ARG D . n 
D 4 363 SER 363 363 363 SER SER D . n 
D 4 364 GLU 364 364 364 GLU GLU D . n 
D 4 365 LEU 365 365 365 LEU LEU D . n 
D 4 366 TYR 366 366 366 TYR TYR D . n 
D 4 367 GLU 367 367 367 GLU GLU D . n 
D 4 368 ALA 368 368 368 ALA ALA D . n 
D 4 369 GLU 369 369 369 GLU GLU D . n 
D 4 370 GLU 370 370 370 GLU GLU D . n 
D 4 371 ARG 371 371 371 ARG ARG D . n 
D 4 372 ALA 372 372 372 ALA ALA D . n 
D 4 373 LEU 373 373 373 LEU LEU D . n 
D 4 374 ARG 374 374 374 ARG ARG D . n 
D 4 375 VAL 375 375 375 VAL VAL D . n 
D 4 376 MET 376 376 376 MET MET D . n 
D 4 377 LEU 377 377 377 LEU LEU D . n 
D 4 378 GLU 378 378 378 GLU GLU D . n 
D 4 379 GLY 379 379 379 GLY GLY D . n 
D 4 380 GLU 380 380 380 GLU GLU D . n 
D 4 381 GLN 381 381 381 GLN GLN D . n 
D 4 382 GLU 382 382 382 GLU GLU D . n 
D 4 383 GLU 383 383 383 GLU GLU D . n 
D 4 384 GLU 384 384 384 GLU GLU D . n 
D 4 385 ARG 385 385 ?   ?   ?   D . n 
D 4 386 LYS 386 386 ?   ?   ?   D . n 
D 4 387 ARG 387 387 ?   ?   ?   D . n 
D 4 388 GLU 388 388 ?   ?   ?   D . n 
D 4 389 LEU 389 389 ?   ?   ?   D . n 
D 4 390 GLU 390 390 ?   ?   ?   D . n 
D 4 391 LYS 391 391 ?   ?   ?   D . n 
D 4 392 LYS 392 392 ?   ?   ?   D . n 
D 4 393 GLN 393 393 ?   ?   ?   D . n 
D 4 394 ARG 394 394 ?   ?   ?   D . n 
D 4 395 LYS 395 395 ?   ?   ?   D . n 
D 4 396 GLU 396 396 ?   ?   ?   D . n 
D 4 397 LYS 397 397 ?   ?   ?   D . n 
D 4 398 GLU 398 398 ?   ?   ?   D . n 
D 4 399 LYS 399 399 ?   ?   ?   D . n 
D 4 400 ILE 400 400 ?   ?   ?   D . n 
D 4 401 LEU 401 401 ?   ?   ?   D . n 
D 4 402 LEU 402 402 ?   ?   ?   D . n 
D 4 403 GLN 403 403 ?   ?   ?   D . n 
D 4 404 LYS 404 404 ?   ?   ?   D . n 
D 4 405 ARG 405 405 ?   ?   ?   D . n 
D 4 406 GLU 406 406 ?   ?   ?   D . n 
D 4 407 ILE 407 407 ?   ?   ?   D . n 
D 4 408 GLU 408 408 ?   ?   ?   D . n 
D 4 409 SER 409 409 ?   ?   ?   D . n 
D 4 410 LYS 410 410 ?   ?   ?   D . n 
D 4 411 LEU 411 411 ?   ?   ?   D . n 
D 4 412 PHE 412 412 ?   ?   ?   D . n 
D 4 413 GLY 413 413 ?   ?   ?   D . n 
D 4 414 ASP 414 414 ?   ?   ?   D . n 
D 4 415 PRO 415 415 ?   ?   ?   D . n 
D 4 416 ASP 416 416 ?   ?   ?   D . n 
D 4 417 GLU 417 417 ?   ?   ?   D . n 
D 4 418 PHE 418 418 ?   ?   ?   D . n 
D 4 419 PRO 419 419 ?   ?   ?   D . n 
D 4 420 LEU 420 420 ?   ?   ?   D . n 
D 4 421 ALA 421 421 ?   ?   ?   D . n 
D 4 422 HIS 422 422 ?   ?   ?   D . n 
D 4 423 LEU 423 423 ?   ?   ?   D . n 
D 4 424 LEU 424 424 ?   ?   ?   D . n 
D 4 425 GLU 425 425 ?   ?   ?   D . n 
D 4 426 PRO 426 426 ?   ?   ?   D . n 
D 4 427 PHE 427 427 ?   ?   ?   D . n 
D 4 428 ARG 428 428 ?   ?   ?   D . n 
D 4 429 GLN 429 429 ?   ?   ?   D . n 
D 4 430 TYR 430 430 ?   ?   ?   D . n 
D 4 431 TYR 431 431 ?   ?   ?   D . n 
D 4 432 LEU 432 432 ?   ?   ?   D . n 
D 4 433 GLN 433 433 ?   ?   ?   D . n 
D 4 434 ALA 434 434 ?   ?   ?   D . n 
D 4 435 GLU 435 435 ?   ?   ?   D . n 
D 4 436 HIS 436 436 ?   ?   ?   D . n 
D 4 437 SER 437 437 ?   ?   ?   D . n 
D 4 438 LEU 438 438 ?   ?   ?   D . n 
D 4 439 PRO 439 439 ?   ?   ?   D . n 
D 4 440 ALA 440 440 ?   ?   ?   D . n 
D 4 441 LEU 441 441 ?   ?   ?   D . n 
D 4 442 ILE 442 442 ?   ?   ?   D . n 
D 4 443 GLN 443 443 ?   ?   ?   D . n 
D 4 444 ILE 444 444 ?   ?   ?   D . n 
D 4 445 ARG 445 445 ?   ?   ?   D . n 
D 4 446 HIS 446 446 ?   ?   ?   D . n 
D 4 447 ASP 447 447 ?   ?   ?   D . n 
D 4 448 TRP 448 448 ?   ?   ?   D . n 
D 4 449 ASP 449 449 ?   ?   ?   D . n 
D 4 450 GLN 450 450 ?   ?   ?   D . n 
D 4 451 TYR 451 451 ?   ?   ?   D . n 
D 4 452 LEU 452 452 ?   ?   ?   D . n 
D 4 453 VAL 453 453 ?   ?   ?   D . n 
D 4 454 PRO 454 454 ?   ?   ?   D . n 
D 4 455 SER 455 455 ?   ?   ?   D . n 
D 4 456 ASP 456 456 ?   ?   ?   D . n 
D 4 457 HIS 457 457 ?   ?   ?   D . n 
D 4 458 PRO 458 458 ?   ?   ?   D . n 
D 4 459 LYS 459 459 ?   ?   ?   D . n 
D 4 460 GLY 460 460 ?   ?   ?   D . n 
D 4 461 ASN 461 461 ?   ?   ?   D . n 
D 4 462 PHE 462 462 ?   ?   ?   D . n 
D 4 463 VAL 463 463 ?   ?   ?   D . n 
D 4 464 PRO 464 464 ?   ?   ?   D . n 
D 4 465 GLN 465 465 ?   ?   ?   D . n 
D 4 466 GLY 466 466 ?   ?   ?   D . n 
D 4 467 TRP 467 467 ?   ?   ?   D . n 
D 4 468 VAL 468 468 ?   ?   ?   D . n 
D 4 469 LEU 469 469 ?   ?   ?   D . n 
D 4 470 PRO 470 470 ?   ?   ?   D . n 
D 4 471 PRO 471 471 ?   ?   ?   D . n 
D 4 472 LEU 472 472 ?   ?   ?   D . n 
D 4 473 PRO 473 473 ?   ?   ?   D . n 
D 4 474 SER 474 474 ?   ?   ?   D . n 
D 4 475 ASN 475 475 ?   ?   ?   D . n 
D 4 476 ASP 476 476 ?   ?   ?   D . n 
D 4 477 ILE 477 477 ?   ?   ?   D . n 
D 4 478 TRP 478 478 ?   ?   ?   D . n 
D 4 479 ALA 479 479 ?   ?   ?   D . n 
D 4 480 THR 480 480 ?   ?   ?   D . n 
D 4 481 ALA 481 481 ?   ?   ?   D . n 
D 4 482 VAL 482 482 ?   ?   ?   D . n 
D 4 483 LYS 483 483 ?   ?   ?   D . n 
D 4 484 LEU 484 484 ?   ?   ?   D . n 
D 4 485 HIS 485 485 ?   ?   ?   D . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GCM 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GCM 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GCM 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9GCM 
_struct.title                        'Structure of the U11 snRNP core' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GCM 
_struct_keywords.text            'minor spliceosome, U11 snRNP, RNA-protein complex, SPLICING' 
_struct_keywords.pdbx_keywords   SPLICING 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 GB  NR_004407.1 161169046 ? 1 
;AAAAAGGGCUUCUGUCGUGAGUGGCACACGUAGGGCAACUCGAUUGCUCUGCGUGCGGAAUCGACAUCAAGAGAUUUCGG
AAGCAUAAUUUUUUGGUAUUUGGGCAGCUGGUGAUCGUUGGUCCCGGCGCCCUUU
;
1 
2 UNP SNR25_HUMAN Q9BV90    ? 2 
;MDVFQEGLAMVVQDPLLCDLPIQVTLEEVNSQIALEYGQAMTVRVCKMDGEVMPVVVVQSATVLDLKKAIQRYVQLKQER
EGGIQHISWSYVWRTYHLTSAGEKLTEDRKKLRDYGIRNRDEVSFIKKLRQK
;
1 
3 UNP U1SBP_HUMAN Q16560    ? 3 
;MNDWMPIAKEYDPLKAGSIDGTDEDPHDRAVWRAMLARYVPNKGVIGDPLLTLFVARLNLQTKEDKLKEVFSRYGDIRRL
RLVRDLVTGFSKGYAFIEYKEERAVIKAYRDADGLVIDQHEIFVDYELERTLKGWIPRRLGGGLGGKKESGQLRFGGRDR
PFRKPINLPVVKNDLYREGKRERRERSRSRERHWDSRTRDRDHDRGREKRWQEREPTRVWPDNDWERERDFRDDRIKGRE
KKERGK
;
1 
4 UNP PDCD7_HUMAN Q8N8D1    ? 4 
;MALPPFFGQGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGGGGAGAF
YPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRLRDRQWLEAVFGTPRRAGCP
VPQRTHAGPSLGEVRARLLRALRLVRRLRGLSQALREAEADGAAWVLLYSQTAPLRAELAERLQPLTQAAYVGEARRRLE
RVRRRRLRLRERAREREAEREAEAARAVEREQEIDRWRVKCVQEVEEKKREQELKAAADGVLSEVRKKQADTKRMVDILR
ALEKLRKLRKEAAARKGVCPPASADETFTHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERKRELEKKQRKEKEKI
LLQKREIESKLFGDPDEFPLAHLLEPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNFVPQGWVLPPLPSNDIWAT
AVKLH
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9GCM A 1 ? 135 ? 161169046 1 ? 135 ? 1 135 
2 2 9GCM B 1 ? 132 ? Q9BV90    1 ? 132 ? 1 132 
3 3 9GCM C 1 ? 246 ? Q16560    1 ? 246 ? 1 246 
4 4 9GCM D 1 ? 485 ? Q8N8D1    1 ? 485 ? 1 485 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP B 2   ? GLN B 13  ? ASP B 2   GLN B 13  1 ? 12 
HELX_P HELX_P2  AA2 ASP B 14  ? CYS B 18  ? ASP B 14  CYS B 18  5 ? 5  
HELX_P HELX_P3  AA3 THR B 25  ? TYR B 37  ? THR B 25  TYR B 37  1 ? 13 
HELX_P HELX_P4  AA4 THR B 62  ? GLY B 82  ? THR B 62  GLY B 82  1 ? 21 
HELX_P HELX_P5  AA5 SER B 88  ? THR B 95  ? SER B 88  THR B 95  1 ? 8  
HELX_P HELX_P6  AA6 ASP C 12  ? GLY C 17  ? ASP C 12  GLY C 17  1 ? 6  
HELX_P HELX_P7  AA7 ASP C 28  ? ALA C 37  ? ASP C 28  ALA C 37  1 ? 10 
HELX_P HELX_P8  AA8 ASP C 48  ? LEU C 50  ? ASP C 48  LEU C 50  5 ? 3  
HELX_P HELX_P9  AA9 LYS C 63  ? SER C 72  ? LYS C 63  SER C 72  1 ? 10 
HELX_P HELX_P10 AB1 ARG C 73  ? GLY C 75  ? ARG C 73  GLY C 75  5 ? 3  
HELX_P HELX_P11 AB2 GLU C 101 ? ASP C 113 ? GLU C 101 ASP C 113 1 ? 13 
HELX_P HELX_P12 AB3 LYS C 148 ? GLY C 151 ? LYS C 148 GLY C 151 5 ? 4  
HELX_P HELX_P13 AB4 GLN D 292 ? ALA D 332 ? GLN D 292 ALA D 332 1 ? 41 
HELX_P HELX_P14 AB5 ALA D 332 ? GLY D 337 ? ALA D 332 GLY D 337 1 ? 6  
HELX_P HELX_P15 AB6 PRO D 340 ? GLU D 384 ? PRO D 340 GLU D 384 1 ? 45 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
hydrog1  hydrog ? ? A U 11 N3 ? ? ? 1_555 A A 81 N1 ? ? A U 11 A A 81 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog2  hydrog ? ? A U 11 O4 ? ? ? 1_555 A A 81 N6 ? ? A U 11 A A 81 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog3  hydrog ? ? A C 12 N3 ? ? ? 1_555 A G 80 N1 ? ? A C 12 A G 80 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog4  hydrog ? ? A C 12 N4 ? ? ? 1_555 A G 80 O6 ? ? A C 12 A G 80 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog5  hydrog ? ? A C 12 O2 ? ? ? 1_555 A G 80 N2 ? ? A C 12 A G 80 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog6  hydrog ? ? A U 13 N3 ? ? ? 1_555 A A 26 N1 ? ? A U 13 A A 26 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog7  hydrog ? ? A U 13 O4 ? ? ? 1_555 A A 26 N6 ? ? A U 13 A A 26 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog8  hydrog ? ? A G 14 N1 ? ? ? 1_555 A C 25 N3 ? ? A G 14 A C 25 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog9  hydrog ? ? A G 14 N2 ? ? ? 1_555 A C 25 O2 ? ? A G 14 A C 25 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog10 hydrog ? ? A G 14 O6 ? ? ? 1_555 A C 25 N4 ? ? A G 14 A C 25 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog11 hydrog ? ? A U 15 N3 ? ? ? 1_555 A G 24 O6 ? ? A U 15 A G 24 1_555 ? ? ? ? ? ? TYPE_28_PAIR  ? ? ? 
hydrog12 hydrog ? ? A U 15 O2 ? ? ? 1_555 A G 24 N1 ? ? A U 15 A G 24 1_555 ? ? ? ? ? ? TYPE_28_PAIR  ? ? ? 
hydrog13 hydrog ? ? A C 16 N3 ? ? ? 1_555 A G 23 N1 ? ? A C 16 A G 23 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog14 hydrog ? ? A C 16 N4 ? ? ? 1_555 A G 23 O6 ? ? A C 16 A G 23 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog15 hydrog ? ? A C 16 O2 ? ? ? 1_555 A G 23 N2 ? ? A C 16 A G 23 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog16 hydrog ? ? A C 27 N3 ? ? ? 1_555 A G 55 N1 ? ? A C 27 A G 55 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog17 hydrog ? ? A C 27 N4 ? ? ? 1_555 A G 55 O6 ? ? A C 27 A G 55 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog18 hydrog ? ? A C 27 O2 ? ? ? 1_555 A G 55 N2 ? ? A C 27 A G 55 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog19 hydrog ? ? A A 28 N1 ? ? ? 1_555 A U 54 N3 ? ? A A 28 A U 54 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog20 hydrog ? ? A A 28 N6 ? ? ? 1_555 A U 54 O4 ? ? A A 28 A U 54 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog21 hydrog ? ? A C 29 N3 ? ? ? 1_555 A G 53 N1 ? ? A C 29 A G 53 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog22 hydrog ? ? A C 29 N4 ? ? ? 1_555 A G 53 O6 ? ? A C 29 A G 53 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog23 hydrog ? ? A C 29 O2 ? ? ? 1_555 A G 53 N2 ? ? A C 29 A G 53 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog24 hydrog ? ? A G 30 N1 ? ? ? 1_555 A C 52 N3 ? ? A G 30 A C 52 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog25 hydrog ? ? A G 30 N2 ? ? ? 1_555 A C 52 O2 ? ? A G 30 A C 52 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog26 hydrog ? ? A G 30 O6 ? ? ? 1_555 A C 52 N4 ? ? A G 30 A C 52 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog27 hydrog ? ? A U 31 N3 ? ? ? 1_555 A G 51 O6 ? ? A U 31 A G 51 1_555 ? ? ? ? ? ? TYPE_28_PAIR  ? ? ? 
hydrog28 hydrog ? ? A U 31 O2 ? ? ? 1_555 A G 51 N1 ? ? A U 31 A G 51 1_555 ? ? ? ? ? ? TYPE_28_PAIR  ? ? ? 
hydrog29 hydrog ? ? A A 32 N1 ? ? ? 1_555 A U 50 N3 ? ? A A 32 A U 50 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog30 hydrog ? ? A A 32 N6 ? ? ? 1_555 A U 50 O4 ? ? A A 32 A U 50 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog31 hydrog ? ? A G 33 N1 ? ? ? 1_555 A C 49 N3 ? ? A G 33 A C 49 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog32 hydrog ? ? A G 33 N2 ? ? ? 1_555 A C 49 O2 ? ? A G 33 A C 49 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog33 hydrog ? ? A G 33 O6 ? ? ? 1_555 A C 49 N4 ? ? A G 33 A C 49 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog34 hydrog ? ? A G 34 N1 ? ? ? 1_555 A U 48 O2 ? ? A G 34 A U 48 1_555 ? ? ? ? ? ? TYPE_28_PAIR  ? ? ? 
hydrog35 hydrog ? ? A G 34 O6 ? ? ? 1_555 A U 48 N3 ? ? A G 34 A U 48 1_555 ? ? ? ? ? ? TYPE_28_PAIR  ? ? ? 
hydrog36 hydrog ? ? A G 35 N1 ? ? ? 1_555 A C 47 N3 ? ? A G 35 A C 47 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog37 hydrog ? ? A G 35 N2 ? ? ? 1_555 A C 47 O2 ? ? A G 35 A C 47 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog38 hydrog ? ? A G 35 O6 ? ? ? 1_555 A C 47 N4 ? ? A G 35 A C 47 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog39 hydrog ? ? A C 36 N3 ? ? ? 1_555 A G 46 N1 ? ? A C 36 A G 46 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog40 hydrog ? ? A C 36 N4 ? ? ? 1_555 A G 46 O6 ? ? A C 36 A G 46 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog41 hydrog ? ? A C 36 O2 ? ? ? 1_555 A G 46 N2 ? ? A C 36 A G 46 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog42 hydrog ? ? A A 37 N1 ? ? ? 1_555 A U 45 N3 ? ? A A 37 A U 45 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog43 hydrog ? ? A A 37 N6 ? ? ? 1_555 A U 45 O4 ? ? A A 37 A U 45 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog44 hydrog ? ? A A 38 N1 ? ? ? 1_555 A U 44 N3 ? ? A A 38 A U 44 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog45 hydrog ? ? A A 38 N6 ? ? ? 1_555 A U 44 O4 ? ? A A 38 A U 44 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog46 hydrog ? ? A C 56 N3 ? ? ? 1_555 A G 79 N1 ? ? A C 56 A G 79 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog47 hydrog ? ? A C 56 N4 ? ? ? 1_555 A G 79 O6 ? ? A C 56 A G 79 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog48 hydrog ? ? A C 56 O2 ? ? ? 1_555 A G 79 N2 ? ? A C 56 A G 79 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog49 hydrog ? ? A G 57 N1 ? ? ? 1_555 A C 78 N3 ? ? A G 57 A C 78 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog50 hydrog ? ? A G 57 N2 ? ? ? 1_555 A C 78 O2 ? ? A G 57 A C 78 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog51 hydrog ? ? A G 57 O6 ? ? ? 1_555 A C 78 N4 ? ? A G 57 A C 78 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog52 hydrog ? ? A G 58 N1 ? ? ? 1_555 A U 77 O2 ? ? A G 58 A U 77 1_555 ? ? ? ? ? ? TYPE_28_PAIR  ? ? ? 
hydrog53 hydrog ? ? A G 58 O6 ? ? ? 1_555 A U 77 N3 ? ? A G 58 A U 77 1_555 ? ? ? ? ? ? TYPE_28_PAIR  ? ? ? 
hydrog54 hydrog ? ? A A 59 N1 ? ? ? 1_555 A U 76 N3 ? ? A A 59 A U 76 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog55 hydrog ? ? A A 59 N6 ? ? ? 1_555 A U 76 O4 ? ? A A 59 A U 76 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog56 hydrog ? ? A A 60 N1 ? ? ? 1_555 A U 75 N3 ? ? A A 60 A U 75 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog57 hydrog ? ? A A 60 N6 ? ? ? 1_555 A U 75 O4 ? ? A A 60 A U 75 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog58 hydrog ? ? A U 61 N3 ? ? ? 1_555 A A 74 N1 ? ? A U 61 A A 74 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog59 hydrog ? ? A U 61 O4 ? ? ? 1_555 A A 74 N6 ? ? A U 61 A A 74 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog60 hydrog ? ? A C 62 N3 ? ? ? 1_555 A G 73 N1 ? ? A C 62 A G 73 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog61 hydrog ? ? A C 62 N4 ? ? ? 1_555 A G 73 O6 ? ? A C 62 A G 73 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog62 hydrog ? ? A C 62 O2 ? ? ? 1_555 A G 73 N2 ? ? A C 62 A G 73 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog63 hydrog ? ? A G 63 N2 ? ? ? 1_555 A A 72 N3 ? ? A G 63 A A 72 1_555 ? ? ? ? ? ? 'G-A MISPAIR' ? ? ? 
# 
_struct_conn_type.id          hydrog 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 4 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL B 52  ? VAL B 58  ? VAL B 52  VAL B 58  
AA1 2 ALA B 40  ? CYS B 46  ? ALA B 40  CYS B 46  
AA1 3 ASP B 121 ? LYS B 127 ? ASP B 121 LYS B 127 
AA1 4 TYR B 96  ? SER B 100 ? TYR B 96  SER B 100 
AA1 5 GLU B 103 ? LYS B 104 ? GLU B 103 LYS B 104 
AA2 1 ILE C 77  ? ARG C 84  ? ILE C 77  ARG C 84  
AA2 2 SER C 91  ? TYR C 99  ? SER C 91  TYR C 99  
AA2 3 THR C 52  ? ALA C 56  ? THR C 52  ALA C 56  
AA2 4 PHE C 123 ? VAL C 124 ? PHE C 123 VAL C 124 
AA3 1 VAL C 116 ? ILE C 117 ? VAL C 116 ILE C 117 
AA3 2 HIS C 120 ? GLU C 121 ? HIS C 120 GLU C 121 
AA4 1 GLY C 146 ? LYS C 147 ? GLY C 146 LYS C 147 
AA4 2 GLN C 152 ? LEU C 153 ? GLN C 152 LEU C 153 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O VAL B 55  ? O VAL B 55  N VAL B 43  ? N VAL B 43  
AA1 2 3 N ARG B 44  ? N ARG B 44  O ASP B 121 ? O ASP B 121 
AA1 3 4 O ILE B 126 ? O ILE B 126 N HIS B 97  ? N HIS B 97  
AA1 4 5 N SER B 100 ? N SER B 100 O GLU B 103 ? O GLU B 103 
AA2 1 2 N VAL C 83  ? N VAL C 83  O LYS C 92  ? O LYS C 92  
AA2 2 3 O ILE C 97  ? O ILE C 97  N LEU C 53  ? N LEU C 53  
AA2 3 4 N ALA C 56  ? N ALA C 56  O PHE C 123 ? O PHE C 123 
AA3 1 2 N ILE C 117 ? N ILE C 117 O HIS C 120 ? O HIS C 120 
AA4 1 2 O LYS C 147 ? O LYS C 147 N GLN C 152 ? N GLN C 152 
# 
_pdbx_entry_details.entry_id                   9GCM 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   "O2'" 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   G 
_pdbx_validate_close_contact.auth_seq_id_1    63 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OG 
_pdbx_validate_close_contact.auth_asym_id_2   C 
_pdbx_validate_close_contact.auth_comp_id_2   SER 
_pdbx_validate_close_contact.auth_seq_id_2    150 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.14 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LEU B 17  ? ? -140.88 11.11  
2 1 ILE B 22  ? ? 51.44   -92.89 
3 1 THR B 25  ? ? 61.95   160.39 
4 1 GLU C 101 ? ? 69.52   133.89 
5 1 SER C 150 ? ? -85.03  49.22  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9GCM 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   'Cross-correction coefficient' 
_em_3d_fitting.details           'refinement is done in Phenix' 
_em_3d_fitting.overall_b_value   71.2 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'RIGID BODY FIT' 
# 
loop_
_em_3d_fitting_list.id 
_em_3d_fitting_list.3d_fitting_id 
_em_3d_fitting_list.pdb_entry_id 
_em_3d_fitting_list.pdb_chain_id 
_em_3d_fitting_list.pdb_chain_residue_range 
_em_3d_fitting_list.details 
_em_3d_fitting_list.chain_id 
_em_3d_fitting_list.chain_residue_range 
_em_3d_fitting_list.source_name 
_em_3d_fitting_list.type 
_em_3d_fitting_list.accession_code 
_em_3d_fitting_list.initial_refinement_model_id 
1 1 . . . ? B 1-132 AlphaFold 'in silico model' AF-Q9BV90-F1 1 
2 1 . . . ? C 1-246 AlphaFold 'in silico model' AF-Q16560-F1 2 
3 1 . . . ? D 1-485 AlphaFold 'in silico model' AF-Q8N8D1-F1 3 
# 
_em_3d_reconstruction.entry_id                    9GCM 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.1 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               268233 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       
;20 mM HEPES-KOH, pH 7.9
200 mM KCl
2 mM MgCl2
;
_em_buffer.pH            7.9 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Structure  of the U11 snRNP core' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4' 
# 
_em_image_scans.entry_id                9GCM 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        4096 
_em_image_scans.dimension_width         4096 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        9GCM 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         'Preliminary grid screening was performed on Glacios.' 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             700 
_em_imaging.nominal_defocus_max             1700 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           165000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'ZEMLIN TABLEAU' 
_em_imaging.c2_aperture_diameter            50.0 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    ? 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        'UltrAuFoil R2/2' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9GCM 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277.15 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9GCM 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A A   1   ? A A   1   
2   1 Y 1 A A   2   ? A A   2   
3   1 Y 1 A A   3   ? A A   3   
4   1 Y 1 A A   4   ? A A   4   
5   1 Y 1 A A   5   ? A A   5   
6   1 Y 1 A G   6   ? A G   6   
7   1 Y 1 A G   7   ? A G   7   
8   1 Y 1 A G   8   ? A G   8   
9   1 Y 1 A C   9   ? A C   9   
10  1 Y 1 A U   10  ? A U   10  
11  1 Y 1 A C   39  ? A C   39  
12  1 Y 1 A U   40  ? A U   40  
13  1 Y 1 A C   41  ? A C   41  
14  1 Y 1 A G   42  ? A G   42  
15  1 Y 1 A A   43  ? A A   43  
16  1 Y 1 A A   82  ? A A   82  
17  1 Y 1 A G   83  ? A G   83  
18  1 Y 1 A C   84  ? A C   84  
19  1 Y 1 A A   85  ? A A   85  
20  1 Y 1 A U   86  ? A U   86  
21  1 Y 1 A A   87  ? A A   87  
22  1 Y 1 A A   88  ? A A   88  
23  1 Y 1 A U   89  ? A U   89  
24  1 Y 1 A U   90  ? A U   90  
25  1 Y 1 A U   91  ? A U   91  
26  1 Y 1 A U   92  ? A U   92  
27  1 Y 1 A U   93  ? A U   93  
28  1 Y 1 A U   94  ? A U   94  
29  1 Y 1 A G   95  ? A G   95  
30  1 Y 1 A G   96  ? A G   96  
31  1 Y 1 A U   97  ? A U   97  
32  1 Y 1 A A   98  ? A A   98  
33  1 Y 1 A U   99  ? A U   99  
34  1 Y 1 A U   100 ? A U   100 
35  1 Y 1 A U   101 ? A U   101 
36  1 Y 1 A G   102 ? A G   102 
37  1 Y 1 A G   103 ? A G   103 
38  1 Y 1 A G   104 ? A G   104 
39  1 Y 1 A C   105 ? A C   105 
40  1 Y 1 A A   106 ? A A   106 
41  1 Y 1 A G   107 ? A G   107 
42  1 Y 1 A C   108 ? A C   108 
43  1 Y 1 A U   109 ? A U   109 
44  1 Y 1 A G   110 ? A G   110 
45  1 Y 1 A G   111 ? A G   111 
46  1 Y 1 A U   112 ? A U   112 
47  1 Y 1 A G   113 ? A G   113 
48  1 Y 1 A A   114 ? A A   114 
49  1 Y 1 A U   115 ? A U   115 
50  1 Y 1 A C   116 ? A C   116 
51  1 Y 1 A G   117 ? A G   117 
52  1 Y 1 A U   118 ? A U   118 
53  1 Y 1 A U   119 ? A U   119 
54  1 Y 1 A G   120 ? A G   120 
55  1 Y 1 A G   121 ? A G   121 
56  1 Y 1 A U   122 ? A U   122 
57  1 Y 1 A C   123 ? A C   123 
58  1 Y 1 A C   124 ? A C   124 
59  1 Y 1 A C   125 ? A C   125 
60  1 Y 1 A G   126 ? A G   126 
61  1 Y 1 A G   127 ? A G   127 
62  1 Y 1 A C   128 ? A C   128 
63  1 Y 1 A G   129 ? A G   129 
64  1 Y 1 A C   130 ? A C   130 
65  1 Y 1 A C   131 ? A C   131 
66  1 Y 1 A C   132 ? A C   132 
67  1 Y 1 A U   133 ? A U   133 
68  1 Y 1 A U   134 ? A U   134 
69  1 Y 1 A U   135 ? A U   135 
70  1 Y 1 B LEU 129 ? B LEU 129 
71  1 Y 1 B ARG 130 ? B ARG 130 
72  1 Y 1 B GLN 131 ? B GLN 131 
73  1 Y 1 B LYS 132 ? B LYS 132 
74  1 Y 1 C MET 1   ? C MET 1   
75  1 Y 1 C ASN 2   ? C ASN 2   
76  1 Y 1 C ASP 3   ? C ASP 3   
77  1 Y 1 C TRP 4   ? C TRP 4   
78  1 Y 1 C MET 5   ? C MET 5   
79  1 Y 1 C PRO 6   ? C PRO 6   
80  1 Y 1 C ILE 7   ? C ILE 7   
81  1 Y 1 C ALA 8   ? C ALA 8   
82  1 Y 1 C LYS 9   ? C LYS 9   
83  1 Y 1 C PRO 165 ? C PRO 165 
84  1 Y 1 C ILE 166 ? C ILE 166 
85  1 Y 1 C ASN 167 ? C ASN 167 
86  1 Y 1 C LEU 168 ? C LEU 168 
87  1 Y 1 C PRO 169 ? C PRO 169 
88  1 Y 1 C VAL 170 ? C VAL 170 
89  1 Y 1 C VAL 171 ? C VAL 171 
90  1 Y 1 C LYS 172 ? C LYS 172 
91  1 Y 1 C ASN 173 ? C ASN 173 
92  1 Y 1 C ASP 174 ? C ASP 174 
93  1 Y 1 C LEU 175 ? C LEU 175 
94  1 Y 1 C TYR 176 ? C TYR 176 
95  1 Y 1 C ARG 177 ? C ARG 177 
96  1 Y 1 C GLU 178 ? C GLU 178 
97  1 Y 1 C GLY 179 ? C GLY 179 
98  1 Y 1 C LYS 180 ? C LYS 180 
99  1 Y 1 C ARG 181 ? C ARG 181 
100 1 Y 1 C GLU 182 ? C GLU 182 
101 1 Y 1 C ARG 183 ? C ARG 183 
102 1 Y 1 C ARG 184 ? C ARG 184 
103 1 Y 1 C GLU 185 ? C GLU 185 
104 1 Y 1 C ARG 186 ? C ARG 186 
105 1 Y 1 C SER 187 ? C SER 187 
106 1 Y 1 C ARG 188 ? C ARG 188 
107 1 Y 1 C SER 189 ? C SER 189 
108 1 Y 1 C ARG 190 ? C ARG 190 
109 1 Y 1 C GLU 191 ? C GLU 191 
110 1 Y 1 C ARG 192 ? C ARG 192 
111 1 Y 1 C HIS 193 ? C HIS 193 
112 1 Y 1 C TRP 194 ? C TRP 194 
113 1 Y 1 C ASP 195 ? C ASP 195 
114 1 Y 1 C SER 196 ? C SER 196 
115 1 Y 1 C ARG 197 ? C ARG 197 
116 1 Y 1 C THR 198 ? C THR 198 
117 1 Y 1 C ARG 199 ? C ARG 199 
118 1 Y 1 C ASP 200 ? C ASP 200 
119 1 Y 1 C ARG 201 ? C ARG 201 
120 1 Y 1 C ASP 202 ? C ASP 202 
121 1 Y 1 C HIS 203 ? C HIS 203 
122 1 Y 1 C ASP 204 ? C ASP 204 
123 1 Y 1 C ARG 205 ? C ARG 205 
124 1 Y 1 C GLY 206 ? C GLY 206 
125 1 Y 1 C ARG 207 ? C ARG 207 
126 1 Y 1 C GLU 208 ? C GLU 208 
127 1 Y 1 C LYS 209 ? C LYS 209 
128 1 Y 1 C ARG 210 ? C ARG 210 
129 1 Y 1 C TRP 211 ? C TRP 211 
130 1 Y 1 C GLN 212 ? C GLN 212 
131 1 Y 1 C GLU 213 ? C GLU 213 
132 1 Y 1 C ARG 214 ? C ARG 214 
133 1 Y 1 C GLU 215 ? C GLU 215 
134 1 Y 1 C PRO 216 ? C PRO 216 
135 1 Y 1 C THR 217 ? C THR 217 
136 1 Y 1 C ARG 218 ? C ARG 218 
137 1 Y 1 C VAL 219 ? C VAL 219 
138 1 Y 1 C TRP 220 ? C TRP 220 
139 1 Y 1 C PRO 221 ? C PRO 221 
140 1 Y 1 C ASP 222 ? C ASP 222 
141 1 Y 1 C ASN 223 ? C ASN 223 
142 1 Y 1 C ASP 224 ? C ASP 224 
143 1 Y 1 C TRP 225 ? C TRP 225 
144 1 Y 1 C GLU 226 ? C GLU 226 
145 1 Y 1 C ARG 227 ? C ARG 227 
146 1 Y 1 C GLU 228 ? C GLU 228 
147 1 Y 1 C ARG 229 ? C ARG 229 
148 1 Y 1 C ASP 230 ? C ASP 230 
149 1 Y 1 C PHE 231 ? C PHE 231 
150 1 Y 1 C ARG 232 ? C ARG 232 
151 1 Y 1 C ASP 233 ? C ASP 233 
152 1 Y 1 C ASP 234 ? C ASP 234 
153 1 Y 1 C ARG 235 ? C ARG 235 
154 1 Y 1 C ILE 236 ? C ILE 236 
155 1 Y 1 C LYS 237 ? C LYS 237 
156 1 Y 1 C GLY 238 ? C GLY 238 
157 1 Y 1 C ARG 239 ? C ARG 239 
158 1 Y 1 C GLU 240 ? C GLU 240 
159 1 Y 1 C LYS 241 ? C LYS 241 
160 1 Y 1 C LYS 242 ? C LYS 242 
161 1 Y 1 C GLU 243 ? C GLU 243 
162 1 Y 1 C ARG 244 ? C ARG 244 
163 1 Y 1 C GLY 245 ? C GLY 245 
164 1 Y 1 C LYS 246 ? C LYS 246 
165 1 Y 1 D MET 1   ? D MET 1   
166 1 Y 1 D ALA 2   ? D ALA 2   
167 1 Y 1 D LEU 3   ? D LEU 3   
168 1 Y 1 D PRO 4   ? D PRO 4   
169 1 Y 1 D PRO 5   ? D PRO 5   
170 1 Y 1 D PHE 6   ? D PHE 6   
171 1 Y 1 D PHE 7   ? D PHE 7   
172 1 Y 1 D GLY 8   ? D GLY 8   
173 1 Y 1 D GLN 9   ? D GLN 9   
174 1 Y 1 D GLY 10  ? D GLY 10  
175 1 Y 1 D ARG 11  ? D ARG 11  
176 1 Y 1 D PRO 12  ? D PRO 12  
177 1 Y 1 D GLY 13  ? D GLY 13  
178 1 Y 1 D PRO 14  ? D PRO 14  
179 1 Y 1 D PRO 15  ? D PRO 15  
180 1 Y 1 D PRO 16  ? D PRO 16  
181 1 Y 1 D PRO 17  ? D PRO 17  
182 1 Y 1 D GLN 18  ? D GLN 18  
183 1 Y 1 D PRO 19  ? D PRO 19  
184 1 Y 1 D PRO 20  ? D PRO 20  
185 1 Y 1 D PRO 21  ? D PRO 21  
186 1 Y 1 D PRO 22  ? D PRO 22  
187 1 Y 1 D ALA 23  ? D ALA 23  
188 1 Y 1 D PRO 24  ? D PRO 24  
189 1 Y 1 D PHE 25  ? D PHE 25  
190 1 Y 1 D GLY 26  ? D GLY 26  
191 1 Y 1 D CYS 27  ? D CYS 27  
192 1 Y 1 D PRO 28  ? D PRO 28  
193 1 Y 1 D PRO 29  ? D PRO 29  
194 1 Y 1 D PRO 30  ? D PRO 30  
195 1 Y 1 D PRO 31  ? D PRO 31  
196 1 Y 1 D LEU 32  ? D LEU 32  
197 1 Y 1 D PRO 33  ? D PRO 33  
198 1 Y 1 D SER 34  ? D SER 34  
199 1 Y 1 D PRO 35  ? D PRO 35  
200 1 Y 1 D ALA 36  ? D ALA 36  
201 1 Y 1 D PHE 37  ? D PHE 37  
202 1 Y 1 D PRO 38  ? D PRO 38  
203 1 Y 1 D PRO 39  ? D PRO 39  
204 1 Y 1 D PRO 40  ? D PRO 40  
205 1 Y 1 D LEU 41  ? D LEU 41  
206 1 Y 1 D PRO 42  ? D PRO 42  
207 1 Y 1 D GLN 43  ? D GLN 43  
208 1 Y 1 D ARG 44  ? D ARG 44  
209 1 Y 1 D PRO 45  ? D PRO 45  
210 1 Y 1 D GLY 46  ? D GLY 46  
211 1 Y 1 D PRO 47  ? D PRO 47  
212 1 Y 1 D PHE 48  ? D PHE 48  
213 1 Y 1 D PRO 49  ? D PRO 49  
214 1 Y 1 D GLY 50  ? D GLY 50  
215 1 Y 1 D ALA 51  ? D ALA 51  
216 1 Y 1 D SER 52  ? D SER 52  
217 1 Y 1 D ALA 53  ? D ALA 53  
218 1 Y 1 D PRO 54  ? D PRO 54  
219 1 Y 1 D PHE 55  ? D PHE 55  
220 1 Y 1 D LEU 56  ? D LEU 56  
221 1 Y 1 D GLN 57  ? D GLN 57  
222 1 Y 1 D PRO 58  ? D PRO 58  
223 1 Y 1 D PRO 59  ? D PRO 59  
224 1 Y 1 D LEU 60  ? D LEU 60  
225 1 Y 1 D ALA 61  ? D ALA 61  
226 1 Y 1 D LEU 62  ? D LEU 62  
227 1 Y 1 D GLN 63  ? D GLN 63  
228 1 Y 1 D PRO 64  ? D PRO 64  
229 1 Y 1 D ARG 65  ? D ARG 65  
230 1 Y 1 D ALA 66  ? D ALA 66  
231 1 Y 1 D SER 67  ? D SER 67  
232 1 Y 1 D ALA 68  ? D ALA 68  
233 1 Y 1 D GLU 69  ? D GLU 69  
234 1 Y 1 D ALA 70  ? D ALA 70  
235 1 Y 1 D SER 71  ? D SER 71  
236 1 Y 1 D ARG 72  ? D ARG 72  
237 1 Y 1 D GLY 73  ? D GLY 73  
238 1 Y 1 D GLY 74  ? D GLY 74  
239 1 Y 1 D GLY 75  ? D GLY 75  
240 1 Y 1 D GLY 76  ? D GLY 76  
241 1 Y 1 D ALA 77  ? D ALA 77  
242 1 Y 1 D GLY 78  ? D GLY 78  
243 1 Y 1 D ALA 79  ? D ALA 79  
244 1 Y 1 D PHE 80  ? D PHE 80  
245 1 Y 1 D TYR 81  ? D TYR 81  
246 1 Y 1 D PRO 82  ? D PRO 82  
247 1 Y 1 D VAL 83  ? D VAL 83  
248 1 Y 1 D PRO 84  ? D PRO 84  
249 1 Y 1 D PRO 85  ? D PRO 85  
250 1 Y 1 D PRO 86  ? D PRO 86  
251 1 Y 1 D PRO 87  ? D PRO 87  
252 1 Y 1 D LEU 88  ? D LEU 88  
253 1 Y 1 D PRO 89  ? D PRO 89  
254 1 Y 1 D PRO 90  ? D PRO 90  
255 1 Y 1 D PRO 91  ? D PRO 91  
256 1 Y 1 D PRO 92  ? D PRO 92  
257 1 Y 1 D PRO 93  ? D PRO 93  
258 1 Y 1 D GLN 94  ? D GLN 94  
259 1 Y 1 D CYS 95  ? D CYS 95  
260 1 Y 1 D ARG 96  ? D ARG 96  
261 1 Y 1 D PRO 97  ? D PRO 97  
262 1 Y 1 D PHE 98  ? D PHE 98  
263 1 Y 1 D PRO 99  ? D PRO 99  
264 1 Y 1 D GLY 100 ? D GLY 100 
265 1 Y 1 D THR 101 ? D THR 101 
266 1 Y 1 D ASP 102 ? D ASP 102 
267 1 Y 1 D ALA 103 ? D ALA 103 
268 1 Y 1 D GLY 104 ? D GLY 104 
269 1 Y 1 D GLU 105 ? D GLU 105 
270 1 Y 1 D ARG 106 ? D ARG 106 
271 1 Y 1 D PRO 107 ? D PRO 107 
272 1 Y 1 D ARG 108 ? D ARG 108 
273 1 Y 1 D PRO 109 ? D PRO 109 
274 1 Y 1 D PRO 110 ? D PRO 110 
275 1 Y 1 D PRO 111 ? D PRO 111 
276 1 Y 1 D PRO 112 ? D PRO 112 
277 1 Y 1 D GLY 113 ? D GLY 113 
278 1 Y 1 D PRO 114 ? D PRO 114 
279 1 Y 1 D GLY 115 ? D GLY 115 
280 1 Y 1 D PRO 116 ? D PRO 116 
281 1 Y 1 D PRO 117 ? D PRO 117 
282 1 Y 1 D TRP 118 ? D TRP 118 
283 1 Y 1 D SER 119 ? D SER 119 
284 1 Y 1 D PRO 120 ? D PRO 120 
285 1 Y 1 D ARG 121 ? D ARG 121 
286 1 Y 1 D TRP 122 ? D TRP 122 
287 1 Y 1 D PRO 123 ? D PRO 123 
288 1 Y 1 D GLU 124 ? D GLU 124 
289 1 Y 1 D ALA 125 ? D ALA 125 
290 1 Y 1 D PRO 126 ? D PRO 126 
291 1 Y 1 D PRO 127 ? D PRO 127 
292 1 Y 1 D PRO 128 ? D PRO 128 
293 1 Y 1 D PRO 129 ? D PRO 129 
294 1 Y 1 D ALA 130 ? D ALA 130 
295 1 Y 1 D ASP 131 ? D ASP 131 
296 1 Y 1 D VAL 132 ? D VAL 132 
297 1 Y 1 D LEU 133 ? D LEU 133 
298 1 Y 1 D GLY 134 ? D GLY 134 
299 1 Y 1 D ASP 135 ? D ASP 135 
300 1 Y 1 D ALA 136 ? D ALA 136 
301 1 Y 1 D ALA 137 ? D ALA 137 
302 1 Y 1 D LEU 138 ? D LEU 138 
303 1 Y 1 D GLN 139 ? D GLN 139 
304 1 Y 1 D ARG 140 ? D ARG 140 
305 1 Y 1 D LEU 141 ? D LEU 141 
306 1 Y 1 D ARG 142 ? D ARG 142 
307 1 Y 1 D ASP 143 ? D ASP 143 
308 1 Y 1 D ARG 144 ? D ARG 144 
309 1 Y 1 D GLN 145 ? D GLN 145 
310 1 Y 1 D TRP 146 ? D TRP 146 
311 1 Y 1 D LEU 147 ? D LEU 147 
312 1 Y 1 D GLU 148 ? D GLU 148 
313 1 Y 1 D ALA 149 ? D ALA 149 
314 1 Y 1 D VAL 150 ? D VAL 150 
315 1 Y 1 D PHE 151 ? D PHE 151 
316 1 Y 1 D GLY 152 ? D GLY 152 
317 1 Y 1 D THR 153 ? D THR 153 
318 1 Y 1 D PRO 154 ? D PRO 154 
319 1 Y 1 D ARG 155 ? D ARG 155 
320 1 Y 1 D ARG 156 ? D ARG 156 
321 1 Y 1 D ALA 157 ? D ALA 157 
322 1 Y 1 D GLY 158 ? D GLY 158 
323 1 Y 1 D CYS 159 ? D CYS 159 
324 1 Y 1 D PRO 160 ? D PRO 160 
325 1 Y 1 D VAL 161 ? D VAL 161 
326 1 Y 1 D PRO 162 ? D PRO 162 
327 1 Y 1 D GLN 163 ? D GLN 163 
328 1 Y 1 D ARG 164 ? D ARG 164 
329 1 Y 1 D THR 165 ? D THR 165 
330 1 Y 1 D HIS 166 ? D HIS 166 
331 1 Y 1 D ALA 167 ? D ALA 167 
332 1 Y 1 D GLY 168 ? D GLY 168 
333 1 Y 1 D PRO 169 ? D PRO 169 
334 1 Y 1 D SER 170 ? D SER 170 
335 1 Y 1 D LEU 171 ? D LEU 171 
336 1 Y 1 D GLY 172 ? D GLY 172 
337 1 Y 1 D GLU 173 ? D GLU 173 
338 1 Y 1 D VAL 174 ? D VAL 174 
339 1 Y 1 D ARG 175 ? D ARG 175 
340 1 Y 1 D ALA 176 ? D ALA 176 
341 1 Y 1 D ARG 177 ? D ARG 177 
342 1 Y 1 D LEU 178 ? D LEU 178 
343 1 Y 1 D LEU 179 ? D LEU 179 
344 1 Y 1 D ARG 180 ? D ARG 180 
345 1 Y 1 D ALA 181 ? D ALA 181 
346 1 Y 1 D LEU 182 ? D LEU 182 
347 1 Y 1 D ARG 183 ? D ARG 183 
348 1 Y 1 D LEU 184 ? D LEU 184 
349 1 Y 1 D VAL 185 ? D VAL 185 
350 1 Y 1 D ARG 186 ? D ARG 186 
351 1 Y 1 D ARG 187 ? D ARG 187 
352 1 Y 1 D LEU 188 ? D LEU 188 
353 1 Y 1 D ARG 189 ? D ARG 189 
354 1 Y 1 D GLY 190 ? D GLY 190 
355 1 Y 1 D LEU 191 ? D LEU 191 
356 1 Y 1 D SER 192 ? D SER 192 
357 1 Y 1 D GLN 193 ? D GLN 193 
358 1 Y 1 D ALA 194 ? D ALA 194 
359 1 Y 1 D LEU 195 ? D LEU 195 
360 1 Y 1 D ARG 196 ? D ARG 196 
361 1 Y 1 D GLU 197 ? D GLU 197 
362 1 Y 1 D ALA 198 ? D ALA 198 
363 1 Y 1 D GLU 199 ? D GLU 199 
364 1 Y 1 D ALA 200 ? D ALA 200 
365 1 Y 1 D ASP 201 ? D ASP 201 
366 1 Y 1 D GLY 202 ? D GLY 202 
367 1 Y 1 D ALA 203 ? D ALA 203 
368 1 Y 1 D ALA 204 ? D ALA 204 
369 1 Y 1 D TRP 205 ? D TRP 205 
370 1 Y 1 D VAL 206 ? D VAL 206 
371 1 Y 1 D LEU 207 ? D LEU 207 
372 1 Y 1 D LEU 208 ? D LEU 208 
373 1 Y 1 D TYR 209 ? D TYR 209 
374 1 Y 1 D SER 210 ? D SER 210 
375 1 Y 1 D GLN 211 ? D GLN 211 
376 1 Y 1 D THR 212 ? D THR 212 
377 1 Y 1 D ALA 213 ? D ALA 213 
378 1 Y 1 D PRO 214 ? D PRO 214 
379 1 Y 1 D LEU 215 ? D LEU 215 
380 1 Y 1 D ARG 216 ? D ARG 216 
381 1 Y 1 D ALA 217 ? D ALA 217 
382 1 Y 1 D GLU 218 ? D GLU 218 
383 1 Y 1 D LEU 219 ? D LEU 219 
384 1 Y 1 D ALA 220 ? D ALA 220 
385 1 Y 1 D GLU 221 ? D GLU 221 
386 1 Y 1 D ARG 222 ? D ARG 222 
387 1 Y 1 D LEU 223 ? D LEU 223 
388 1 Y 1 D GLN 224 ? D GLN 224 
389 1 Y 1 D PRO 225 ? D PRO 225 
390 1 Y 1 D LEU 226 ? D LEU 226 
391 1 Y 1 D THR 227 ? D THR 227 
392 1 Y 1 D GLN 228 ? D GLN 228 
393 1 Y 1 D ALA 229 ? D ALA 229 
394 1 Y 1 D ALA 230 ? D ALA 230 
395 1 Y 1 D TYR 231 ? D TYR 231 
396 1 Y 1 D VAL 232 ? D VAL 232 
397 1 Y 1 D GLY 233 ? D GLY 233 
398 1 Y 1 D GLU 234 ? D GLU 234 
399 1 Y 1 D ALA 235 ? D ALA 235 
400 1 Y 1 D ARG 236 ? D ARG 236 
401 1 Y 1 D ARG 237 ? D ARG 237 
402 1 Y 1 D ARG 238 ? D ARG 238 
403 1 Y 1 D LEU 239 ? D LEU 239 
404 1 Y 1 D GLU 240 ? D GLU 240 
405 1 Y 1 D ARG 241 ? D ARG 241 
406 1 Y 1 D VAL 242 ? D VAL 242 
407 1 Y 1 D ARG 243 ? D ARG 243 
408 1 Y 1 D ARG 244 ? D ARG 244 
409 1 Y 1 D ARG 245 ? D ARG 245 
410 1 Y 1 D ARG 246 ? D ARG 246 
411 1 Y 1 D LEU 247 ? D LEU 247 
412 1 Y 1 D ARG 248 ? D ARG 248 
413 1 Y 1 D LEU 249 ? D LEU 249 
414 1 Y 1 D ARG 250 ? D ARG 250 
415 1 Y 1 D GLU 251 ? D GLU 251 
416 1 Y 1 D ARG 252 ? D ARG 252 
417 1 Y 1 D ALA 253 ? D ALA 253 
418 1 Y 1 D ARG 254 ? D ARG 254 
419 1 Y 1 D GLU 255 ? D GLU 255 
420 1 Y 1 D ARG 256 ? D ARG 256 
421 1 Y 1 D GLU 257 ? D GLU 257 
422 1 Y 1 D ALA 258 ? D ALA 258 
423 1 Y 1 D GLU 259 ? D GLU 259 
424 1 Y 1 D ARG 260 ? D ARG 260 
425 1 Y 1 D GLU 261 ? D GLU 261 
426 1 Y 1 D ALA 262 ? D ALA 262 
427 1 Y 1 D GLU 263 ? D GLU 263 
428 1 Y 1 D ALA 264 ? D ALA 264 
429 1 Y 1 D ALA 265 ? D ALA 265 
430 1 Y 1 D ARG 266 ? D ARG 266 
431 1 Y 1 D ALA 267 ? D ALA 267 
432 1 Y 1 D VAL 268 ? D VAL 268 
433 1 Y 1 D GLU 269 ? D GLU 269 
434 1 Y 1 D ARG 270 ? D ARG 270 
435 1 Y 1 D GLU 271 ? D GLU 271 
436 1 Y 1 D GLN 272 ? D GLN 272 
437 1 Y 1 D GLU 273 ? D GLU 273 
438 1 Y 1 D ILE 274 ? D ILE 274 
439 1 Y 1 D ASP 275 ? D ASP 275 
440 1 Y 1 D ARG 276 ? D ARG 276 
441 1 Y 1 D TRP 277 ? D TRP 277 
442 1 Y 1 D ARG 278 ? D ARG 278 
443 1 Y 1 D VAL 279 ? D VAL 279 
444 1 Y 1 D LYS 280 ? D LYS 280 
445 1 Y 1 D CYS 281 ? D CYS 281 
446 1 Y 1 D VAL 282 ? D VAL 282 
447 1 Y 1 D GLN 283 ? D GLN 283 
448 1 Y 1 D GLU 284 ? D GLU 284 
449 1 Y 1 D VAL 285 ? D VAL 285 
450 1 Y 1 D GLU 286 ? D GLU 286 
451 1 Y 1 D GLU 287 ? D GLU 287 
452 1 Y 1 D LYS 288 ? D LYS 288 
453 1 Y 1 D LYS 289 ? D LYS 289 
454 1 Y 1 D ARG 290 ? D ARG 290 
455 1 Y 1 D ARG 385 ? D ARG 385 
456 1 Y 1 D LYS 386 ? D LYS 386 
457 1 Y 1 D ARG 387 ? D ARG 387 
458 1 Y 1 D GLU 388 ? D GLU 388 
459 1 Y 1 D LEU 389 ? D LEU 389 
460 1 Y 1 D GLU 390 ? D GLU 390 
461 1 Y 1 D LYS 391 ? D LYS 391 
462 1 Y 1 D LYS 392 ? D LYS 392 
463 1 Y 1 D GLN 393 ? D GLN 393 
464 1 Y 1 D ARG 394 ? D ARG 394 
465 1 Y 1 D LYS 395 ? D LYS 395 
466 1 Y 1 D GLU 396 ? D GLU 396 
467 1 Y 1 D LYS 397 ? D LYS 397 
468 1 Y 1 D GLU 398 ? D GLU 398 
469 1 Y 1 D LYS 399 ? D LYS 399 
470 1 Y 1 D ILE 400 ? D ILE 400 
471 1 Y 1 D LEU 401 ? D LEU 401 
472 1 Y 1 D LEU 402 ? D LEU 402 
473 1 Y 1 D GLN 403 ? D GLN 403 
474 1 Y 1 D LYS 404 ? D LYS 404 
475 1 Y 1 D ARG 405 ? D ARG 405 
476 1 Y 1 D GLU 406 ? D GLU 406 
477 1 Y 1 D ILE 407 ? D ILE 407 
478 1 Y 1 D GLU 408 ? D GLU 408 
479 1 Y 1 D SER 409 ? D SER 409 
480 1 Y 1 D LYS 410 ? D LYS 410 
481 1 Y 1 D LEU 411 ? D LEU 411 
482 1 Y 1 D PHE 412 ? D PHE 412 
483 1 Y 1 D GLY 413 ? D GLY 413 
484 1 Y 1 D ASP 414 ? D ASP 414 
485 1 Y 1 D PRO 415 ? D PRO 415 
486 1 Y 1 D ASP 416 ? D ASP 416 
487 1 Y 1 D GLU 417 ? D GLU 417 
488 1 Y 1 D PHE 418 ? D PHE 418 
489 1 Y 1 D PRO 419 ? D PRO 419 
490 1 Y 1 D LEU 420 ? D LEU 420 
491 1 Y 1 D ALA 421 ? D ALA 421 
492 1 Y 1 D HIS 422 ? D HIS 422 
493 1 Y 1 D LEU 423 ? D LEU 423 
494 1 Y 1 D LEU 424 ? D LEU 424 
495 1 Y 1 D GLU 425 ? D GLU 425 
496 1 Y 1 D PRO 426 ? D PRO 426 
497 1 Y 1 D PHE 427 ? D PHE 427 
498 1 Y 1 D ARG 428 ? D ARG 428 
499 1 Y 1 D GLN 429 ? D GLN 429 
500 1 Y 1 D TYR 430 ? D TYR 430 
501 1 Y 1 D TYR 431 ? D TYR 431 
502 1 Y 1 D LEU 432 ? D LEU 432 
503 1 Y 1 D GLN 433 ? D GLN 433 
504 1 Y 1 D ALA 434 ? D ALA 434 
505 1 Y 1 D GLU 435 ? D GLU 435 
506 1 Y 1 D HIS 436 ? D HIS 436 
507 1 Y 1 D SER 437 ? D SER 437 
508 1 Y 1 D LEU 438 ? D LEU 438 
509 1 Y 1 D PRO 439 ? D PRO 439 
510 1 Y 1 D ALA 440 ? D ALA 440 
511 1 Y 1 D LEU 441 ? D LEU 441 
512 1 Y 1 D ILE 442 ? D ILE 442 
513 1 Y 1 D GLN 443 ? D GLN 443 
514 1 Y 1 D ILE 444 ? D ILE 444 
515 1 Y 1 D ARG 445 ? D ARG 445 
516 1 Y 1 D HIS 446 ? D HIS 446 
517 1 Y 1 D ASP 447 ? D ASP 447 
518 1 Y 1 D TRP 448 ? D TRP 448 
519 1 Y 1 D ASP 449 ? D ASP 449 
520 1 Y 1 D GLN 450 ? D GLN 450 
521 1 Y 1 D TYR 451 ? D TYR 451 
522 1 Y 1 D LEU 452 ? D LEU 452 
523 1 Y 1 D VAL 453 ? D VAL 453 
524 1 Y 1 D PRO 454 ? D PRO 454 
525 1 Y 1 D SER 455 ? D SER 455 
526 1 Y 1 D ASP 456 ? D ASP 456 
527 1 Y 1 D HIS 457 ? D HIS 457 
528 1 Y 1 D PRO 458 ? D PRO 458 
529 1 Y 1 D LYS 459 ? D LYS 459 
530 1 Y 1 D GLY 460 ? D GLY 460 
531 1 Y 1 D ASN 461 ? D ASN 461 
532 1 Y 1 D PHE 462 ? D PHE 462 
533 1 Y 1 D VAL 463 ? D VAL 463 
534 1 Y 1 D PRO 464 ? D PRO 464 
535 1 Y 1 D GLN 465 ? D GLN 465 
536 1 Y 1 D GLY 466 ? D GLY 466 
537 1 Y 1 D TRP 467 ? D TRP 467 
538 1 Y 1 D VAL 468 ? D VAL 468 
539 1 Y 1 D LEU 469 ? D LEU 469 
540 1 Y 1 D PRO 470 ? D PRO 470 
541 1 Y 1 D PRO 471 ? D PRO 471 
542 1 Y 1 D LEU 472 ? D LEU 472 
543 1 Y 1 D PRO 473 ? D PRO 473 
544 1 Y 1 D SER 474 ? D SER 474 
545 1 Y 1 D ASN 475 ? D ASN 475 
546 1 Y 1 D ASP 476 ? D ASP 476 
547 1 Y 1 D ILE 477 ? D ILE 477 
548 1 Y 1 D TRP 478 ? D TRP 478 
549 1 Y 1 D ALA 479 ? D ALA 479 
550 1 Y 1 D THR 480 ? D THR 480 
551 1 Y 1 D ALA 481 ? D ALA 481 
552 1 Y 1 D VAL 482 ? D VAL 482 
553 1 Y 1 D LYS 483 ? D LYS 483 
554 1 Y 1 D LEU 484 ? D LEU 484 
555 1 Y 1 D HIS 485 ? D HIS 485 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A   OP3    O N N 1   
A   P      P N N 2   
A   OP1    O N N 3   
A   OP2    O N N 4   
A   "O5'"  O N N 5   
A   "C5'"  C N N 6   
A   "C4'"  C N R 7   
A   "O4'"  O N N 8   
A   "C3'"  C N S 9   
A   "O3'"  O N N 10  
A   "C2'"  C N R 11  
A   "O2'"  O N N 12  
A   "C1'"  C N R 13  
A   N9     N Y N 14  
A   C8     C Y N 15  
A   N7     N Y N 16  
A   C5     C Y N 17  
A   C6     C Y N 18  
A   N6     N N N 19  
A   N1     N Y N 20  
A   C2     C Y N 21  
A   N3     N Y N 22  
A   C4     C Y N 23  
A   HOP3   H N N 24  
A   HOP2   H N N 25  
A   "H5'"  H N N 26  
A   "H5''" H N N 27  
A   "H4'"  H N N 28  
A   "H3'"  H N N 29  
A   "HO3'" H N N 30  
A   "H2'"  H N N 31  
A   "HO2'" H N N 32  
A   "H1'"  H N N 33  
A   H8     H N N 34  
A   H61    H N N 35  
A   H62    H N N 36  
A   H2     H N N 37  
ALA N      N N N 38  
ALA CA     C N S 39  
ALA C      C N N 40  
ALA O      O N N 41  
ALA CB     C N N 42  
ALA OXT    O N N 43  
ALA H      H N N 44  
ALA H2     H N N 45  
ALA HA     H N N 46  
ALA HB1    H N N 47  
ALA HB2    H N N 48  
ALA HB3    H N N 49  
ALA HXT    H N N 50  
ARG N      N N N 51  
ARG CA     C N S 52  
ARG C      C N N 53  
ARG O      O N N 54  
ARG CB     C N N 55  
ARG CG     C N N 56  
ARG CD     C N N 57  
ARG NE     N N N 58  
ARG CZ     C N N 59  
ARG NH1    N N N 60  
ARG NH2    N N N 61  
ARG OXT    O N N 62  
ARG H      H N N 63  
ARG H2     H N N 64  
ARG HA     H N N 65  
ARG HB2    H N N 66  
ARG HB3    H N N 67  
ARG HG2    H N N 68  
ARG HG3    H N N 69  
ARG HD2    H N N 70  
ARG HD3    H N N 71  
ARG HE     H N N 72  
ARG HH11   H N N 73  
ARG HH12   H N N 74  
ARG HH21   H N N 75  
ARG HH22   H N N 76  
ARG HXT    H N N 77  
ASN N      N N N 78  
ASN CA     C N S 79  
ASN C      C N N 80  
ASN O      O N N 81  
ASN CB     C N N 82  
ASN CG     C N N 83  
ASN OD1    O N N 84  
ASN ND2    N N N 85  
ASN OXT    O N N 86  
ASN H      H N N 87  
ASN H2     H N N 88  
ASN HA     H N N 89  
ASN HB2    H N N 90  
ASN HB3    H N N 91  
ASN HD21   H N N 92  
ASN HD22   H N N 93  
ASN HXT    H N N 94  
ASP N      N N N 95  
ASP CA     C N S 96  
ASP C      C N N 97  
ASP O      O N N 98  
ASP CB     C N N 99  
ASP CG     C N N 100 
ASP OD1    O N N 101 
ASP OD2    O N N 102 
ASP OXT    O N N 103 
ASP H      H N N 104 
ASP H2     H N N 105 
ASP HA     H N N 106 
ASP HB2    H N N 107 
ASP HB3    H N N 108 
ASP HD2    H N N 109 
ASP HXT    H N N 110 
C   OP3    O N N 111 
C   P      P N N 112 
C   OP1    O N N 113 
C   OP2    O N N 114 
C   "O5'"  O N N 115 
C   "C5'"  C N N 116 
C   "C4'"  C N R 117 
C   "O4'"  O N N 118 
C   "C3'"  C N S 119 
C   "O3'"  O N N 120 
C   "C2'"  C N R 121 
C   "O2'"  O N N 122 
C   "C1'"  C N R 123 
C   N1     N N N 124 
C   C2     C N N 125 
C   O2     O N N 126 
C   N3     N N N 127 
C   C4     C N N 128 
C   N4     N N N 129 
C   C5     C N N 130 
C   C6     C N N 131 
C   HOP3   H N N 132 
C   HOP2   H N N 133 
C   "H5'"  H N N 134 
C   "H5''" H N N 135 
C   "H4'"  H N N 136 
C   "H3'"  H N N 137 
C   "HO3'" H N N 138 
C   "H2'"  H N N 139 
C   "HO2'" H N N 140 
C   "H1'"  H N N 141 
C   H41    H N N 142 
C   H42    H N N 143 
C   H5     H N N 144 
C   H6     H N N 145 
CYS N      N N N 146 
CYS CA     C N R 147 
CYS C      C N N 148 
CYS O      O N N 149 
CYS CB     C N N 150 
CYS SG     S N N 151 
CYS OXT    O N N 152 
CYS H      H N N 153 
CYS H2     H N N 154 
CYS HA     H N N 155 
CYS HB2    H N N 156 
CYS HB3    H N N 157 
CYS HG     H N N 158 
CYS HXT    H N N 159 
G   OP3    O N N 160 
G   P      P N N 161 
G   OP1    O N N 162 
G   OP2    O N N 163 
G   "O5'"  O N N 164 
G   "C5'"  C N N 165 
G   "C4'"  C N R 166 
G   "O4'"  O N N 167 
G   "C3'"  C N S 168 
G   "O3'"  O N N 169 
G   "C2'"  C N R 170 
G   "O2'"  O N N 171 
G   "C1'"  C N R 172 
G   N9     N Y N 173 
G   C8     C Y N 174 
G   N7     N Y N 175 
G   C5     C Y N 176 
G   C6     C N N 177 
G   O6     O N N 178 
G   N1     N N N 179 
G   C2     C N N 180 
G   N2     N N N 181 
G   N3     N N N 182 
G   C4     C Y N 183 
G   HOP3   H N N 184 
G   HOP2   H N N 185 
G   "H5'"  H N N 186 
G   "H5''" H N N 187 
G   "H4'"  H N N 188 
G   "H3'"  H N N 189 
G   "HO3'" H N N 190 
G   "H2'"  H N N 191 
G   "HO2'" H N N 192 
G   "H1'"  H N N 193 
G   H8     H N N 194 
G   H1     H N N 195 
G   H21    H N N 196 
G   H22    H N N 197 
GLN N      N N N 198 
GLN CA     C N S 199 
GLN C      C N N 200 
GLN O      O N N 201 
GLN CB     C N N 202 
GLN CG     C N N 203 
GLN CD     C N N 204 
GLN OE1    O N N 205 
GLN NE2    N N N 206 
GLN OXT    O N N 207 
GLN H      H N N 208 
GLN H2     H N N 209 
GLN HA     H N N 210 
GLN HB2    H N N 211 
GLN HB3    H N N 212 
GLN HG2    H N N 213 
GLN HG3    H N N 214 
GLN HE21   H N N 215 
GLN HE22   H N N 216 
GLN HXT    H N N 217 
GLU N      N N N 218 
GLU CA     C N S 219 
GLU C      C N N 220 
GLU O      O N N 221 
GLU CB     C N N 222 
GLU CG     C N N 223 
GLU CD     C N N 224 
GLU OE1    O N N 225 
GLU OE2    O N N 226 
GLU OXT    O N N 227 
GLU H      H N N 228 
GLU H2     H N N 229 
GLU HA     H N N 230 
GLU HB2    H N N 231 
GLU HB3    H N N 232 
GLU HG2    H N N 233 
GLU HG3    H N N 234 
GLU HE2    H N N 235 
GLU HXT    H N N 236 
GLY N      N N N 237 
GLY CA     C N N 238 
GLY C      C N N 239 
GLY O      O N N 240 
GLY OXT    O N N 241 
GLY H      H N N 242 
GLY H2     H N N 243 
GLY HA2    H N N 244 
GLY HA3    H N N 245 
GLY HXT    H N N 246 
HIS N      N N N 247 
HIS CA     C N S 248 
HIS C      C N N 249 
HIS O      O N N 250 
HIS CB     C N N 251 
HIS CG     C Y N 252 
HIS ND1    N Y N 253 
HIS CD2    C Y N 254 
HIS CE1    C Y N 255 
HIS NE2    N Y N 256 
HIS OXT    O N N 257 
HIS H      H N N 258 
HIS H2     H N N 259 
HIS HA     H N N 260 
HIS HB2    H N N 261 
HIS HB3    H N N 262 
HIS HD1    H N N 263 
HIS HD2    H N N 264 
HIS HE1    H N N 265 
HIS HE2    H N N 266 
HIS HXT    H N N 267 
ILE N      N N N 268 
ILE CA     C N S 269 
ILE C      C N N 270 
ILE O      O N N 271 
ILE CB     C N S 272 
ILE CG1    C N N 273 
ILE CG2    C N N 274 
ILE CD1    C N N 275 
ILE OXT    O N N 276 
ILE H      H N N 277 
ILE H2     H N N 278 
ILE HA     H N N 279 
ILE HB     H N N 280 
ILE HG12   H N N 281 
ILE HG13   H N N 282 
ILE HG21   H N N 283 
ILE HG22   H N N 284 
ILE HG23   H N N 285 
ILE HD11   H N N 286 
ILE HD12   H N N 287 
ILE HD13   H N N 288 
ILE HXT    H N N 289 
LEU N      N N N 290 
LEU CA     C N S 291 
LEU C      C N N 292 
LEU O      O N N 293 
LEU CB     C N N 294 
LEU CG     C N N 295 
LEU CD1    C N N 296 
LEU CD2    C N N 297 
LEU OXT    O N N 298 
LEU H      H N N 299 
LEU H2     H N N 300 
LEU HA     H N N 301 
LEU HB2    H N N 302 
LEU HB3    H N N 303 
LEU HG     H N N 304 
LEU HD11   H N N 305 
LEU HD12   H N N 306 
LEU HD13   H N N 307 
LEU HD21   H N N 308 
LEU HD22   H N N 309 
LEU HD23   H N N 310 
LEU HXT    H N N 311 
LYS N      N N N 312 
LYS CA     C N S 313 
LYS C      C N N 314 
LYS O      O N N 315 
LYS CB     C N N 316 
LYS CG     C N N 317 
LYS CD     C N N 318 
LYS CE     C N N 319 
LYS NZ     N N N 320 
LYS OXT    O N N 321 
LYS H      H N N 322 
LYS H2     H N N 323 
LYS HA     H N N 324 
LYS HB2    H N N 325 
LYS HB3    H N N 326 
LYS HG2    H N N 327 
LYS HG3    H N N 328 
LYS HD2    H N N 329 
LYS HD3    H N N 330 
LYS HE2    H N N 331 
LYS HE3    H N N 332 
LYS HZ1    H N N 333 
LYS HZ2    H N N 334 
LYS HZ3    H N N 335 
LYS HXT    H N N 336 
MET N      N N N 337 
MET CA     C N S 338 
MET C      C N N 339 
MET O      O N N 340 
MET CB     C N N 341 
MET CG     C N N 342 
MET SD     S N N 343 
MET CE     C N N 344 
MET OXT    O N N 345 
MET H      H N N 346 
MET H2     H N N 347 
MET HA     H N N 348 
MET HB2    H N N 349 
MET HB3    H N N 350 
MET HG2    H N N 351 
MET HG3    H N N 352 
MET HE1    H N N 353 
MET HE2    H N N 354 
MET HE3    H N N 355 
MET HXT    H N N 356 
PHE N      N N N 357 
PHE CA     C N S 358 
PHE C      C N N 359 
PHE O      O N N 360 
PHE CB     C N N 361 
PHE CG     C Y N 362 
PHE CD1    C Y N 363 
PHE CD2    C Y N 364 
PHE CE1    C Y N 365 
PHE CE2    C Y N 366 
PHE CZ     C Y N 367 
PHE OXT    O N N 368 
PHE H      H N N 369 
PHE H2     H N N 370 
PHE HA     H N N 371 
PHE HB2    H N N 372 
PHE HB3    H N N 373 
PHE HD1    H N N 374 
PHE HD2    H N N 375 
PHE HE1    H N N 376 
PHE HE2    H N N 377 
PHE HZ     H N N 378 
PHE HXT    H N N 379 
PRO N      N N N 380 
PRO CA     C N S 381 
PRO C      C N N 382 
PRO O      O N N 383 
PRO CB     C N N 384 
PRO CG     C N N 385 
PRO CD     C N N 386 
PRO OXT    O N N 387 
PRO H      H N N 388 
PRO HA     H N N 389 
PRO HB2    H N N 390 
PRO HB3    H N N 391 
PRO HG2    H N N 392 
PRO HG3    H N N 393 
PRO HD2    H N N 394 
PRO HD3    H N N 395 
PRO HXT    H N N 396 
SER N      N N N 397 
SER CA     C N S 398 
SER C      C N N 399 
SER O      O N N 400 
SER CB     C N N 401 
SER OG     O N N 402 
SER OXT    O N N 403 
SER H      H N N 404 
SER H2     H N N 405 
SER HA     H N N 406 
SER HB2    H N N 407 
SER HB3    H N N 408 
SER HG     H N N 409 
SER HXT    H N N 410 
THR N      N N N 411 
THR CA     C N S 412 
THR C      C N N 413 
THR O      O N N 414 
THR CB     C N R 415 
THR OG1    O N N 416 
THR CG2    C N N 417 
THR OXT    O N N 418 
THR H      H N N 419 
THR H2     H N N 420 
THR HA     H N N 421 
THR HB     H N N 422 
THR HG1    H N N 423 
THR HG21   H N N 424 
THR HG22   H N N 425 
THR HG23   H N N 426 
THR HXT    H N N 427 
TRP N      N N N 428 
TRP CA     C N S 429 
TRP C      C N N 430 
TRP O      O N N 431 
TRP CB     C N N 432 
TRP CG     C Y N 433 
TRP CD1    C Y N 434 
TRP CD2    C Y N 435 
TRP NE1    N Y N 436 
TRP CE2    C Y N 437 
TRP CE3    C Y N 438 
TRP CZ2    C Y N 439 
TRP CZ3    C Y N 440 
TRP CH2    C Y N 441 
TRP OXT    O N N 442 
TRP H      H N N 443 
TRP H2     H N N 444 
TRP HA     H N N 445 
TRP HB2    H N N 446 
TRP HB3    H N N 447 
TRP HD1    H N N 448 
TRP HE1    H N N 449 
TRP HE3    H N N 450 
TRP HZ2    H N N 451 
TRP HZ3    H N N 452 
TRP HH2    H N N 453 
TRP HXT    H N N 454 
TYR N      N N N 455 
TYR CA     C N S 456 
TYR C      C N N 457 
TYR O      O N N 458 
TYR CB     C N N 459 
TYR CG     C Y N 460 
TYR CD1    C Y N 461 
TYR CD2    C Y N 462 
TYR CE1    C Y N 463 
TYR CE2    C Y N 464 
TYR CZ     C Y N 465 
TYR OH     O N N 466 
TYR OXT    O N N 467 
TYR H      H N N 468 
TYR H2     H N N 469 
TYR HA     H N N 470 
TYR HB2    H N N 471 
TYR HB3    H N N 472 
TYR HD1    H N N 473 
TYR HD2    H N N 474 
TYR HE1    H N N 475 
TYR HE2    H N N 476 
TYR HH     H N N 477 
TYR HXT    H N N 478 
U   OP3    O N N 479 
U   P      P N N 480 
U   OP1    O N N 481 
U   OP2    O N N 482 
U   "O5'"  O N N 483 
U   "C5'"  C N N 484 
U   "C4'"  C N R 485 
U   "O4'"  O N N 486 
U   "C3'"  C N S 487 
U   "O3'"  O N N 488 
U   "C2'"  C N R 489 
U   "O2'"  O N N 490 
U   "C1'"  C N R 491 
U   N1     N N N 492 
U   C2     C N N 493 
U   O2     O N N 494 
U   N3     N N N 495 
U   C4     C N N 496 
U   O4     O N N 497 
U   C5     C N N 498 
U   C6     C N N 499 
U   HOP3   H N N 500 
U   HOP2   H N N 501 
U   "H5'"  H N N 502 
U   "H5''" H N N 503 
U   "H4'"  H N N 504 
U   "H3'"  H N N 505 
U   "HO3'" H N N 506 
U   "H2'"  H N N 507 
U   "HO2'" H N N 508 
U   "H1'"  H N N 509 
U   H3     H N N 510 
U   H5     H N N 511 
U   H6     H N N 512 
VAL N      N N N 513 
VAL CA     C N S 514 
VAL C      C N N 515 
VAL O      O N N 516 
VAL CB     C N N 517 
VAL CG1    C N N 518 
VAL CG2    C N N 519 
VAL OXT    O N N 520 
VAL H      H N N 521 
VAL H2     H N N 522 
VAL HA     H N N 523 
VAL HB     H N N 524 
VAL HG11   H N N 525 
VAL HG12   H N N 526 
VAL HG13   H N N 527 
VAL HG21   H N N 528 
VAL HG22   H N N 529 
VAL HG23   H N N 530 
VAL HXT    H N N 531 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A   OP3   P      sing N N 1   
A   OP3   HOP3   sing N N 2   
A   P     OP1    doub N N 3   
A   P     OP2    sing N N 4   
A   P     "O5'"  sing N N 5   
A   OP2   HOP2   sing N N 6   
A   "O5'" "C5'"  sing N N 7   
A   "C5'" "C4'"  sing N N 8   
A   "C5'" "H5'"  sing N N 9   
A   "C5'" "H5''" sing N N 10  
A   "C4'" "O4'"  sing N N 11  
A   "C4'" "C3'"  sing N N 12  
A   "C4'" "H4'"  sing N N 13  
A   "O4'" "C1'"  sing N N 14  
A   "C3'" "O3'"  sing N N 15  
A   "C3'" "C2'"  sing N N 16  
A   "C3'" "H3'"  sing N N 17  
A   "O3'" "HO3'" sing N N 18  
A   "C2'" "O2'"  sing N N 19  
A   "C2'" "C1'"  sing N N 20  
A   "C2'" "H2'"  sing N N 21  
A   "O2'" "HO2'" sing N N 22  
A   "C1'" N9     sing N N 23  
A   "C1'" "H1'"  sing N N 24  
A   N9    C8     sing Y N 25  
A   N9    C4     sing Y N 26  
A   C8    N7     doub Y N 27  
A   C8    H8     sing N N 28  
A   N7    C5     sing Y N 29  
A   C5    C6     sing Y N 30  
A   C5    C4     doub Y N 31  
A   C6    N6     sing N N 32  
A   C6    N1     doub Y N 33  
A   N6    H61    sing N N 34  
A   N6    H62    sing N N 35  
A   N1    C2     sing Y N 36  
A   C2    N3     doub Y N 37  
A   C2    H2     sing N N 38  
A   N3    C4     sing Y N 39  
ALA N     CA     sing N N 40  
ALA N     H      sing N N 41  
ALA N     H2     sing N N 42  
ALA CA    C      sing N N 43  
ALA CA    CB     sing N N 44  
ALA CA    HA     sing N N 45  
ALA C     O      doub N N 46  
ALA C     OXT    sing N N 47  
ALA CB    HB1    sing N N 48  
ALA CB    HB2    sing N N 49  
ALA CB    HB3    sing N N 50  
ALA OXT   HXT    sing N N 51  
ARG N     CA     sing N N 52  
ARG N     H      sing N N 53  
ARG N     H2     sing N N 54  
ARG CA    C      sing N N 55  
ARG CA    CB     sing N N 56  
ARG CA    HA     sing N N 57  
ARG C     O      doub N N 58  
ARG C     OXT    sing N N 59  
ARG CB    CG     sing N N 60  
ARG CB    HB2    sing N N 61  
ARG CB    HB3    sing N N 62  
ARG CG    CD     sing N N 63  
ARG CG    HG2    sing N N 64  
ARG CG    HG3    sing N N 65  
ARG CD    NE     sing N N 66  
ARG CD    HD2    sing N N 67  
ARG CD    HD3    sing N N 68  
ARG NE    CZ     sing N N 69  
ARG NE    HE     sing N N 70  
ARG CZ    NH1    sing N N 71  
ARG CZ    NH2    doub N N 72  
ARG NH1   HH11   sing N N 73  
ARG NH1   HH12   sing N N 74  
ARG NH2   HH21   sing N N 75  
ARG NH2   HH22   sing N N 76  
ARG OXT   HXT    sing N N 77  
ASN N     CA     sing N N 78  
ASN N     H      sing N N 79  
ASN N     H2     sing N N 80  
ASN CA    C      sing N N 81  
ASN CA    CB     sing N N 82  
ASN CA    HA     sing N N 83  
ASN C     O      doub N N 84  
ASN C     OXT    sing N N 85  
ASN CB    CG     sing N N 86  
ASN CB    HB2    sing N N 87  
ASN CB    HB3    sing N N 88  
ASN CG    OD1    doub N N 89  
ASN CG    ND2    sing N N 90  
ASN ND2   HD21   sing N N 91  
ASN ND2   HD22   sing N N 92  
ASN OXT   HXT    sing N N 93  
ASP N     CA     sing N N 94  
ASP N     H      sing N N 95  
ASP N     H2     sing N N 96  
ASP CA    C      sing N N 97  
ASP CA    CB     sing N N 98  
ASP CA    HA     sing N N 99  
ASP C     O      doub N N 100 
ASP C     OXT    sing N N 101 
ASP CB    CG     sing N N 102 
ASP CB    HB2    sing N N 103 
ASP CB    HB3    sing N N 104 
ASP CG    OD1    doub N N 105 
ASP CG    OD2    sing N N 106 
ASP OD2   HD2    sing N N 107 
ASP OXT   HXT    sing N N 108 
C   OP3   P      sing N N 109 
C   OP3   HOP3   sing N N 110 
C   P     OP1    doub N N 111 
C   P     OP2    sing N N 112 
C   P     "O5'"  sing N N 113 
C   OP2   HOP2   sing N N 114 
C   "O5'" "C5'"  sing N N 115 
C   "C5'" "C4'"  sing N N 116 
C   "C5'" "H5'"  sing N N 117 
C   "C5'" "H5''" sing N N 118 
C   "C4'" "O4'"  sing N N 119 
C   "C4'" "C3'"  sing N N 120 
C   "C4'" "H4'"  sing N N 121 
C   "O4'" "C1'"  sing N N 122 
C   "C3'" "O3'"  sing N N 123 
C   "C3'" "C2'"  sing N N 124 
C   "C3'" "H3'"  sing N N 125 
C   "O3'" "HO3'" sing N N 126 
C   "C2'" "O2'"  sing N N 127 
C   "C2'" "C1'"  sing N N 128 
C   "C2'" "H2'"  sing N N 129 
C   "O2'" "HO2'" sing N N 130 
C   "C1'" N1     sing N N 131 
C   "C1'" "H1'"  sing N N 132 
C   N1    C2     sing N N 133 
C   N1    C6     sing N N 134 
C   C2    O2     doub N N 135 
C   C2    N3     sing N N 136 
C   N3    C4     doub N N 137 
C   C4    N4     sing N N 138 
C   C4    C5     sing N N 139 
C   N4    H41    sing N N 140 
C   N4    H42    sing N N 141 
C   C5    C6     doub N N 142 
C   C5    H5     sing N N 143 
C   C6    H6     sing N N 144 
CYS N     CA     sing N N 145 
CYS N     H      sing N N 146 
CYS N     H2     sing N N 147 
CYS CA    C      sing N N 148 
CYS CA    CB     sing N N 149 
CYS CA    HA     sing N N 150 
CYS C     O      doub N N 151 
CYS C     OXT    sing N N 152 
CYS CB    SG     sing N N 153 
CYS CB    HB2    sing N N 154 
CYS CB    HB3    sing N N 155 
CYS SG    HG     sing N N 156 
CYS OXT   HXT    sing N N 157 
G   OP3   P      sing N N 158 
G   OP3   HOP3   sing N N 159 
G   P     OP1    doub N N 160 
G   P     OP2    sing N N 161 
G   P     "O5'"  sing N N 162 
G   OP2   HOP2   sing N N 163 
G   "O5'" "C5'"  sing N N 164 
G   "C5'" "C4'"  sing N N 165 
G   "C5'" "H5'"  sing N N 166 
G   "C5'" "H5''" sing N N 167 
G   "C4'" "O4'"  sing N N 168 
G   "C4'" "C3'"  sing N N 169 
G   "C4'" "H4'"  sing N N 170 
G   "O4'" "C1'"  sing N N 171 
G   "C3'" "O3'"  sing N N 172 
G   "C3'" "C2'"  sing N N 173 
G   "C3'" "H3'"  sing N N 174 
G   "O3'" "HO3'" sing N N 175 
G   "C2'" "O2'"  sing N N 176 
G   "C2'" "C1'"  sing N N 177 
G   "C2'" "H2'"  sing N N 178 
G   "O2'" "HO2'" sing N N 179 
G   "C1'" N9     sing N N 180 
G   "C1'" "H1'"  sing N N 181 
G   N9    C8     sing Y N 182 
G   N9    C4     sing Y N 183 
G   C8    N7     doub Y N 184 
G   C8    H8     sing N N 185 
G   N7    C5     sing Y N 186 
G   C5    C6     sing N N 187 
G   C5    C4     doub Y N 188 
G   C6    O6     doub N N 189 
G   C6    N1     sing N N 190 
G   N1    C2     sing N N 191 
G   N1    H1     sing N N 192 
G   C2    N2     sing N N 193 
G   C2    N3     doub N N 194 
G   N2    H21    sing N N 195 
G   N2    H22    sing N N 196 
G   N3    C4     sing N N 197 
GLN N     CA     sing N N 198 
GLN N     H      sing N N 199 
GLN N     H2     sing N N 200 
GLN CA    C      sing N N 201 
GLN CA    CB     sing N N 202 
GLN CA    HA     sing N N 203 
GLN C     O      doub N N 204 
GLN C     OXT    sing N N 205 
GLN CB    CG     sing N N 206 
GLN CB    HB2    sing N N 207 
GLN CB    HB3    sing N N 208 
GLN CG    CD     sing N N 209 
GLN CG    HG2    sing N N 210 
GLN CG    HG3    sing N N 211 
GLN CD    OE1    doub N N 212 
GLN CD    NE2    sing N N 213 
GLN NE2   HE21   sing N N 214 
GLN NE2   HE22   sing N N 215 
GLN OXT   HXT    sing N N 216 
GLU N     CA     sing N N 217 
GLU N     H      sing N N 218 
GLU N     H2     sing N N 219 
GLU CA    C      sing N N 220 
GLU CA    CB     sing N N 221 
GLU CA    HA     sing N N 222 
GLU C     O      doub N N 223 
GLU C     OXT    sing N N 224 
GLU CB    CG     sing N N 225 
GLU CB    HB2    sing N N 226 
GLU CB    HB3    sing N N 227 
GLU CG    CD     sing N N 228 
GLU CG    HG2    sing N N 229 
GLU CG    HG3    sing N N 230 
GLU CD    OE1    doub N N 231 
GLU CD    OE2    sing N N 232 
GLU OE2   HE2    sing N N 233 
GLU OXT   HXT    sing N N 234 
GLY N     CA     sing N N 235 
GLY N     H      sing N N 236 
GLY N     H2     sing N N 237 
GLY CA    C      sing N N 238 
GLY CA    HA2    sing N N 239 
GLY CA    HA3    sing N N 240 
GLY C     O      doub N N 241 
GLY C     OXT    sing N N 242 
GLY OXT   HXT    sing N N 243 
HIS N     CA     sing N N 244 
HIS N     H      sing N N 245 
HIS N     H2     sing N N 246 
HIS CA    C      sing N N 247 
HIS CA    CB     sing N N 248 
HIS CA    HA     sing N N 249 
HIS C     O      doub N N 250 
HIS C     OXT    sing N N 251 
HIS CB    CG     sing N N 252 
HIS CB    HB2    sing N N 253 
HIS CB    HB3    sing N N 254 
HIS CG    ND1    sing Y N 255 
HIS CG    CD2    doub Y N 256 
HIS ND1   CE1    doub Y N 257 
HIS ND1   HD1    sing N N 258 
HIS CD2   NE2    sing Y N 259 
HIS CD2   HD2    sing N N 260 
HIS CE1   NE2    sing Y N 261 
HIS CE1   HE1    sing N N 262 
HIS NE2   HE2    sing N N 263 
HIS OXT   HXT    sing N N 264 
ILE N     CA     sing N N 265 
ILE N     H      sing N N 266 
ILE N     H2     sing N N 267 
ILE CA    C      sing N N 268 
ILE CA    CB     sing N N 269 
ILE CA    HA     sing N N 270 
ILE C     O      doub N N 271 
ILE C     OXT    sing N N 272 
ILE CB    CG1    sing N N 273 
ILE CB    CG2    sing N N 274 
ILE CB    HB     sing N N 275 
ILE CG1   CD1    sing N N 276 
ILE CG1   HG12   sing N N 277 
ILE CG1   HG13   sing N N 278 
ILE CG2   HG21   sing N N 279 
ILE CG2   HG22   sing N N 280 
ILE CG2   HG23   sing N N 281 
ILE CD1   HD11   sing N N 282 
ILE CD1   HD12   sing N N 283 
ILE CD1   HD13   sing N N 284 
ILE OXT   HXT    sing N N 285 
LEU N     CA     sing N N 286 
LEU N     H      sing N N 287 
LEU N     H2     sing N N 288 
LEU CA    C      sing N N 289 
LEU CA    CB     sing N N 290 
LEU CA    HA     sing N N 291 
LEU C     O      doub N N 292 
LEU C     OXT    sing N N 293 
LEU CB    CG     sing N N 294 
LEU CB    HB2    sing N N 295 
LEU CB    HB3    sing N N 296 
LEU CG    CD1    sing N N 297 
LEU CG    CD2    sing N N 298 
LEU CG    HG     sing N N 299 
LEU CD1   HD11   sing N N 300 
LEU CD1   HD12   sing N N 301 
LEU CD1   HD13   sing N N 302 
LEU CD2   HD21   sing N N 303 
LEU CD2   HD22   sing N N 304 
LEU CD2   HD23   sing N N 305 
LEU OXT   HXT    sing N N 306 
LYS N     CA     sing N N 307 
LYS N     H      sing N N 308 
LYS N     H2     sing N N 309 
LYS CA    C      sing N N 310 
LYS CA    CB     sing N N 311 
LYS CA    HA     sing N N 312 
LYS C     O      doub N N 313 
LYS C     OXT    sing N N 314 
LYS CB    CG     sing N N 315 
LYS CB    HB2    sing N N 316 
LYS CB    HB3    sing N N 317 
LYS CG    CD     sing N N 318 
LYS CG    HG2    sing N N 319 
LYS CG    HG3    sing N N 320 
LYS CD    CE     sing N N 321 
LYS CD    HD2    sing N N 322 
LYS CD    HD3    sing N N 323 
LYS CE    NZ     sing N N 324 
LYS CE    HE2    sing N N 325 
LYS CE    HE3    sing N N 326 
LYS NZ    HZ1    sing N N 327 
LYS NZ    HZ2    sing N N 328 
LYS NZ    HZ3    sing N N 329 
LYS OXT   HXT    sing N N 330 
MET N     CA     sing N N 331 
MET N     H      sing N N 332 
MET N     H2     sing N N 333 
MET CA    C      sing N N 334 
MET CA    CB     sing N N 335 
MET CA    HA     sing N N 336 
MET C     O      doub N N 337 
MET C     OXT    sing N N 338 
MET CB    CG     sing N N 339 
MET CB    HB2    sing N N 340 
MET CB    HB3    sing N N 341 
MET CG    SD     sing N N 342 
MET CG    HG2    sing N N 343 
MET CG    HG3    sing N N 344 
MET SD    CE     sing N N 345 
MET CE    HE1    sing N N 346 
MET CE    HE2    sing N N 347 
MET CE    HE3    sing N N 348 
MET OXT   HXT    sing N N 349 
PHE N     CA     sing N N 350 
PHE N     H      sing N N 351 
PHE N     H2     sing N N 352 
PHE CA    C      sing N N 353 
PHE CA    CB     sing N N 354 
PHE CA    HA     sing N N 355 
PHE C     O      doub N N 356 
PHE C     OXT    sing N N 357 
PHE CB    CG     sing N N 358 
PHE CB    HB2    sing N N 359 
PHE CB    HB3    sing N N 360 
PHE CG    CD1    doub Y N 361 
PHE CG    CD2    sing Y N 362 
PHE CD1   CE1    sing Y N 363 
PHE CD1   HD1    sing N N 364 
PHE CD2   CE2    doub Y N 365 
PHE CD2   HD2    sing N N 366 
PHE CE1   CZ     doub Y N 367 
PHE CE1   HE1    sing N N 368 
PHE CE2   CZ     sing Y N 369 
PHE CE2   HE2    sing N N 370 
PHE CZ    HZ     sing N N 371 
PHE OXT   HXT    sing N N 372 
PRO N     CA     sing N N 373 
PRO N     CD     sing N N 374 
PRO N     H      sing N N 375 
PRO CA    C      sing N N 376 
PRO CA    CB     sing N N 377 
PRO CA    HA     sing N N 378 
PRO C     O      doub N N 379 
PRO C     OXT    sing N N 380 
PRO CB    CG     sing N N 381 
PRO CB    HB2    sing N N 382 
PRO CB    HB3    sing N N 383 
PRO CG    CD     sing N N 384 
PRO CG    HG2    sing N N 385 
PRO CG    HG3    sing N N 386 
PRO CD    HD2    sing N N 387 
PRO CD    HD3    sing N N 388 
PRO OXT   HXT    sing N N 389 
SER N     CA     sing N N 390 
SER N     H      sing N N 391 
SER N     H2     sing N N 392 
SER CA    C      sing N N 393 
SER CA    CB     sing N N 394 
SER CA    HA     sing N N 395 
SER C     O      doub N N 396 
SER C     OXT    sing N N 397 
SER CB    OG     sing N N 398 
SER CB    HB2    sing N N 399 
SER CB    HB3    sing N N 400 
SER OG    HG     sing N N 401 
SER OXT   HXT    sing N N 402 
THR N     CA     sing N N 403 
THR N     H      sing N N 404 
THR N     H2     sing N N 405 
THR CA    C      sing N N 406 
THR CA    CB     sing N N 407 
THR CA    HA     sing N N 408 
THR C     O      doub N N 409 
THR C     OXT    sing N N 410 
THR CB    OG1    sing N N 411 
THR CB    CG2    sing N N 412 
THR CB    HB     sing N N 413 
THR OG1   HG1    sing N N 414 
THR CG2   HG21   sing N N 415 
THR CG2   HG22   sing N N 416 
THR CG2   HG23   sing N N 417 
THR OXT   HXT    sing N N 418 
TRP N     CA     sing N N 419 
TRP N     H      sing N N 420 
TRP N     H2     sing N N 421 
TRP CA    C      sing N N 422 
TRP CA    CB     sing N N 423 
TRP CA    HA     sing N N 424 
TRP C     O      doub N N 425 
TRP C     OXT    sing N N 426 
TRP CB    CG     sing N N 427 
TRP CB    HB2    sing N N 428 
TRP CB    HB3    sing N N 429 
TRP CG    CD1    doub Y N 430 
TRP CG    CD2    sing Y N 431 
TRP CD1   NE1    sing Y N 432 
TRP CD1   HD1    sing N N 433 
TRP CD2   CE2    doub Y N 434 
TRP CD2   CE3    sing Y N 435 
TRP NE1   CE2    sing Y N 436 
TRP NE1   HE1    sing N N 437 
TRP CE2   CZ2    sing Y N 438 
TRP CE3   CZ3    doub Y N 439 
TRP CE3   HE3    sing N N 440 
TRP CZ2   CH2    doub Y N 441 
TRP CZ2   HZ2    sing N N 442 
TRP CZ3   CH2    sing Y N 443 
TRP CZ3   HZ3    sing N N 444 
TRP CH2   HH2    sing N N 445 
TRP OXT   HXT    sing N N 446 
TYR N     CA     sing N N 447 
TYR N     H      sing N N 448 
TYR N     H2     sing N N 449 
TYR CA    C      sing N N 450 
TYR CA    CB     sing N N 451 
TYR CA    HA     sing N N 452 
TYR C     O      doub N N 453 
TYR C     OXT    sing N N 454 
TYR CB    CG     sing N N 455 
TYR CB    HB2    sing N N 456 
TYR CB    HB3    sing N N 457 
TYR CG    CD1    doub Y N 458 
TYR CG    CD2    sing Y N 459 
TYR CD1   CE1    sing Y N 460 
TYR CD1   HD1    sing N N 461 
TYR CD2   CE2    doub Y N 462 
TYR CD2   HD2    sing N N 463 
TYR CE1   CZ     doub Y N 464 
TYR CE1   HE1    sing N N 465 
TYR CE2   CZ     sing Y N 466 
TYR CE2   HE2    sing N N 467 
TYR CZ    OH     sing N N 468 
TYR OH    HH     sing N N 469 
TYR OXT   HXT    sing N N 470 
U   OP3   P      sing N N 471 
U   OP3   HOP3   sing N N 472 
U   P     OP1    doub N N 473 
U   P     OP2    sing N N 474 
U   P     "O5'"  sing N N 475 
U   OP2   HOP2   sing N N 476 
U   "O5'" "C5'"  sing N N 477 
U   "C5'" "C4'"  sing N N 478 
U   "C5'" "H5'"  sing N N 479 
U   "C5'" "H5''" sing N N 480 
U   "C4'" "O4'"  sing N N 481 
U   "C4'" "C3'"  sing N N 482 
U   "C4'" "H4'"  sing N N 483 
U   "O4'" "C1'"  sing N N 484 
U   "C3'" "O3'"  sing N N 485 
U   "C3'" "C2'"  sing N N 486 
U   "C3'" "H3'"  sing N N 487 
U   "O3'" "HO3'" sing N N 488 
U   "C2'" "O2'"  sing N N 489 
U   "C2'" "C1'"  sing N N 490 
U   "C2'" "H2'"  sing N N 491 
U   "O2'" "HO2'" sing N N 492 
U   "C1'" N1     sing N N 493 
U   "C1'" "H1'"  sing N N 494 
U   N1    C2     sing N N 495 
U   N1    C6     sing N N 496 
U   C2    O2     doub N N 497 
U   C2    N3     sing N N 498 
U   N3    C4     sing N N 499 
U   N3    H3     sing N N 500 
U   C4    O4     doub N N 501 
U   C4    C5     sing N N 502 
U   C5    C6     doub N N 503 
U   C5    H5     sing N N 504 
U   C6    H6     sing N N 505 
VAL N     CA     sing N N 506 
VAL N     H      sing N N 507 
VAL N     H2     sing N N 508 
VAL CA    C      sing N N 509 
VAL CA    CB     sing N N 510 
VAL CA    HA     sing N N 511 
VAL C     O      doub N N 512 
VAL C     OXT    sing N N 513 
VAL CB    CG1    sing N N 514 
VAL CB    CG2    sing N N 515 
VAL CB    HB     sing N N 516 
VAL CG1   HG11   sing N N 517 
VAL CG1   HG12   sing N N 518 
VAL CG1   HG13   sing N N 519 
VAL CG2   HG21   sing N N 520 
VAL CG2   HG22   sing N N 521 
VAL CG2   HG23   sing N N 522 
VAL OXT   HXT    sing N N 523 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-08-02 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9GCM 
_em_admin.last_update        2025-02-19 
_em_admin.map_release_date   2025-02-05 
_em_admin.title              'Structure of the U11 snRNP core' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 200 mM KCl   1 'potassium chloride' 
1 2   mM MgCl2 2 'magnesium chloride' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.13 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         41.73 
_em_image_recording.details                             'Images were colleted in EER format' 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    2 
_em_image_recording.num_real_images                     30164 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    10 
_em_imaging_optics.energyfilter_name          'TFS Selectris X' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  'Topaz picking is performed with user-trained model' 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   7144222 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? cryoSPARC       v4.3.1 
'IMAGE ACQUISITION'        ? 2  ? ? 1 SerialEM        ?      
MASKING                    ? 3  ? ? ? ?               ?      
'CTF CORRECTION'           ? 4  1 ? ? ?               ?      
'LAYERLINE INDEXING'       ? 5  ? ? ? ?               ?      
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?               ?      
'MODEL FITTING'            ? 7  ? 1 ? 'UCSF ChimeraX' 1.6.1  
OTHER                      ? 8  ? ? ? ?               ?      
'INITIAL EULER ASSIGNMENT' ? 9  1 ? ? cryoSPARC       v4.3.1 
'FINAL EULER ASSIGNMENT'   ? 10 1 ? ? cryoSPARC       v4.3.1 
CLASSIFICATION             ? 11 1 ? ? cryoSPARC       v4.3.1 
RECONSTRUCTION             ? 12 1 ? ? cryoSPARC       v4.3.1 
'MODEL REFINEMENT'         ? 13 ? 1 ? PHENIX          1.20.1 
# 
_em_specimen.concentration           0.2 
_em_specimen.details                 'This sample was monodisperse' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
9GCM 'double helix'         
9GCM 'a-form double helix'  
9GCM 'hairpin loop'         
9GCM 'bulge loop'           
9GCM 'mismatched base pair' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 A U 11 1_555 A A 81 1_555 0.008  -0.169 0.210  -3.019  -2.987 2.950    1  A_U11:A81_A A 11 ? A 81 ? 20 1  
1 A C 12 1_555 A G 80 1_555 0.176  -0.275 0.805  -0.792  -1.568 -0.158   2  A_C12:G80_A A 12 ? A 80 ? 19 1  
1 A C 56 1_555 A G 79 1_555 0.194  -0.262 0.891  0.521   1.266  3.931    3  A_C56:G79_A A 56 ? A 79 ? 19 1  
1 A G 57 1_555 A C 78 1_555 -0.238 -0.130 0.216  -0.500  1.114  2.033    4  A_G57:C78_A A 57 ? A 78 ? 19 1  
1 A G 58 1_555 A U 77 1_555 -2.681 -0.456 -0.186 -0.944  -3.660 2.932    5  A_G58:U77_A A 58 ? A 77 ? 28 1  
1 A A 59 1_555 A U 76 1_555 0.015  -0.107 -0.377 -5.852  -6.638 2.687    6  A_A59:U76_A A 59 ? A 76 ? 20 1  
1 A A 60 1_555 A U 75 1_555 0.155  -0.195 -0.665 -5.429  2.620  -1.544   7  A_A60:U75_A A 60 ? A 75 ? 20 1  
1 A U 61 1_555 A A 74 1_555 -0.039 -0.165 -0.474 0.169   3.708  1.648    8  A_U61:A74_A A 61 ? A 74 ? 20 1  
1 A C 62 1_555 A G 73 1_555 0.184  -0.161 -0.109 3.484   0.703  -0.706   9  A_C62:G73_A A 62 ? A 73 ? 19 1  
1 A G 63 1_555 A A 72 1_555 -2.946 -7.359 1.585  -53.199 0.197  -159.741 10 A_G63:A72_A A 63 ? A 72 ? ?  12 
1 A G 23 1_555 A C 16 1_555 -0.234 -0.211 0.048  -4.541  7.606  -0.133   11 A_G23:C16_A A 23 ? A 16 ? 19 1  
1 A G 24 1_555 A U 15 1_555 -1.417 -0.572 0.091  -2.218  9.008  -3.671   12 A_G24:U15_A A 24 ? A 15 ? 28 1  
1 A C 25 1_555 A G 14 1_555 0.196  -0.143 0.095  3.876   8.050  1.973    13 A_C25:G14_A A 25 ? A 14 ? 19 1  
1 A A 26 1_555 A U 13 1_555 -0.004 -0.220 -0.691 1.138   1.702  5.064    14 A_A26:U13_A A 26 ? A 13 ? 20 1  
1 A C 27 1_555 A G 55 1_555 0.142  -0.297 -1.000 -0.141  0.241  -0.874   15 A_C27:G55_A A 27 ? A 55 ? 19 1  
1 A A 28 1_555 A U 54 1_555 0.092  -0.133 0.318  0.049   9.602  1.966    16 A_A28:U54_A A 28 ? A 54 ? 20 1  
1 A C 29 1_555 A G 53 1_555 0.266  -0.207 0.362  7.175   6.613  2.601    17 A_C29:G53_A A 29 ? A 53 ? 19 1  
1 A G 30 1_555 A C 52 1_555 -0.190 -0.128 0.229  6.352   4.389  2.034    18 A_G30:C52_A A 30 ? A 52 ? 19 1  
1 A U 31 1_555 A G 51 1_555 1.555  -0.583 -0.394 6.783   0.932  0.385    19 A_U31:G51_A A 31 ? A 51 ? 28 1  
1 A A 32 1_555 A U 50 1_555 0.051  -0.278 -0.809 -1.235  1.827  0.232    20 A_A32:U50_A A 32 ? A 50 ? 20 1  
1 A G 33 1_555 A C 49 1_555 -0.126 -0.412 -1.219 -2.911  -0.099 -0.385   21 A_G33:C49_A A 33 ? A 49 ? 19 1  
1 A G 34 1_555 A U 48 1_555 -0.631 -1.023 -1.303 -5.105  6.123  -2.668   22 A_G34:U48_A A 34 ? A 48 ? 28 1  
1 A G 35 1_555 A C 47 1_555 -0.093 -0.394 -1.138 -2.032  7.057  -3.444   23 A_G35:C47_A A 35 ? A 47 ? 19 1  
1 A C 36 1_555 A G 46 1_555 0.123  -0.378 -1.139 5.127   5.033  -2.811   24 A_C36:G46_A A 36 ? A 46 ? 19 1  
1 A A 37 1_555 A U 45 1_555 0.127  -0.285 -1.004 -3.286  2.428  -2.200   25 A_A37:U45_A A 37 ? A 45 ? 20 1  
1 A A 38 1_555 A U 44 1_555 0.094  -0.327 -1.154 -0.590  2.592  0.928    26 A_A38:U44_A A 38 ? A 44 ? 20 1  
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 A U 11 1_555 A A 81 1_555 A C 12 1_555 A G 80 1_555 0.044  -1.270 3.290 -0.445 3.069  32.763  -2.760 -0.152 3.160  5.426  0.787 
32.906  1  AA_U11C12:G80A81_AA A 11 ? A 81 ? A 12 ? A 80 ? 
1 A C 12 1_555 A G 80 1_555 A C 56 1_555 A G 79 1_555 0.497  -1.542 3.003 2.053  7.981  34.754  -3.523 -0.552 2.620  13.133 -3.379 
35.688  2  AA_C12C56:G79G80_AA A 12 ? A 80 ? A 56 ? A 79 ? 
1 A C 56 1_555 A G 79 1_555 A G 57 1_555 A C 78 1_555 0.426  -1.487 3.322 10.062 -4.249 30.075  -1.878 1.176  3.456  -7.870 
-18.635 31.954  3  AA_C56G57:C78G79_AA A 56 ? A 79 ? A 57 ? A 78 ? 
1 A G 57 1_555 A C 78 1_555 A G 58 1_555 A U 77 1_555 0.061  -2.732 2.872 -6.168 26.421 18.683  -6.921 -0.596 -0.541 54.602 12.747 
32.842  4  AA_G57G58:U77C78_AA A 57 ? A 78 ? A 58 ? A 77 ? 
1 A G 58 1_555 A U 77 1_555 A A 59 1_555 A U 76 1_555 -0.789 -1.385 3.589 -1.230 -1.904 44.306  -1.638 0.918  3.662  -2.523 1.630 
44.362  5  AA_G58A59:U76U77_AA A 58 ? A 77 ? A 59 ? A 76 ? 
1 A A 59 1_555 A U 76 1_555 A A 60 1_555 A U 75 1_555 -0.835 -1.181 3.307 -1.757 6.305  31.649  -3.222 1.194  3.061  11.408 3.178 
32.302  6  AA_A59A60:U75U76_AA A 59 ? A 76 ? A 60 ? A 75 ? 
1 A A 60 1_555 A U 75 1_555 A U 61 1_555 A A 74 1_555 0.699  -1.296 3.124 -1.842 4.200  33.293  -2.878 -1.488 2.901  7.287  3.196 
33.598  7  AA_A60U61:A74U75_AA A 60 ? A 75 ? A 61 ? A 74 ? 
1 A U 61 1_555 A A 74 1_555 A C 62 1_555 A G 73 1_555 -0.430 -1.725 3.117 -1.164 5.433  31.212  -4.071 0.592  2.798  9.998  2.142 
31.691  8  AA_U61C62:G73A74_AA A 61 ? A 74 ? A 62 ? A 73 ? 
1 A C 62 1_555 A G 73 1_555 A G 63 1_555 A A 72 1_555 -2.779 0.661  3.806 24.366 24.653 115.229 0.103  1.895  3.464  14.425 
-14.257 118.499 9  AA_C62G63:A72G73_AA A 62 ? A 73 ? A 63 ? A 72 ? 
1 A G 23 1_555 A C 16 1_555 A G 24 1_555 A U 15 1_555 -0.534 -1.979 3.150 -2.914 4.959  29.507  -4.755 0.479  2.826  9.622  5.654 
30.050  10 AA_G23G24:U15C16_AA A 23 ? A 16 ? A 24 ? A 15 ? 
1 A G 24 1_555 A U 15 1_555 A C 25 1_555 A G 14 1_555 0.212  -1.450 3.128 -1.252 4.379  37.518  -2.764 -0.478 2.938  6.777  1.938 
37.783  11 AA_G24C25:G14U15_AA A 24 ? A 15 ? A 25 ? A 14 ? 
1 A C 25 1_555 A G 14 1_555 A A 26 1_555 A U 13 1_555 0.372  -1.682 3.318 3.557  5.836  27.361  -4.776 0.042  2.927  12.100 -7.374 
28.186  12 AA_C25A26:U13G14_AA A 25 ? A 14 ? A 26 ? A 13 ? 
1 A A 26 1_555 A U 13 1_555 A C 27 1_555 A G 55 1_555 1.666  -1.311 3.181 4.247  2.667  49.569  -1.749 -1.673 3.234  3.172  -5.050 
49.806  13 AA_A26C27:G55U13_AA A 26 ? A 13 ? A 27 ? A 55 ? 
1 A C 27 1_555 A G 55 1_555 A A 28 1_555 A U 54 1_555 0.089  -1.400 3.242 -6.682 10.932 29.713  -4.296 -1.247 2.507  20.178 12.333 
32.300  14 AA_C27A28:U54G55_AA A 27 ? A 55 ? A 28 ? A 54 ? 
1 A A 28 1_555 A U 54 1_555 A C 29 1_555 A G 53 1_555 0.486  -1.624 3.101 0.559  6.032  32.809  -3.738 -0.763 2.775  10.567 -0.979 
33.348  15 AA_A28C29:G53U54_AA A 28 ? A 54 ? A 29 ? A 53 ? 
1 A C 29 1_555 A G 53 1_555 A G 30 1_555 A C 52 1_555 0.609  -2.005 2.815 2.813  9.279  32.374  -4.635 -0.690 2.216  16.194 -4.909 
33.758  16 AA_C29G30:C52G53_AA A 29 ? A 53 ? A 30 ? A 52 ? 
1 A G 30 1_555 A C 52 1_555 A U 31 1_555 A G 51 1_555 0.146  -1.577 3.191 4.549  0.809  39.360  -2.419 0.303  3.156  1.196  -6.726 
39.619  17 AA_G30U31:G51C52_AA A 30 ? A 52 ? A 31 ? A 51 ? 
1 A U 31 1_555 A G 51 1_555 A A 32 1_555 A U 50 1_555 -0.021 -1.669 3.680 8.098  8.495  28.990  -4.805 1.665  2.973  16.159 
-15.404 31.229  18 AA_U31A32:U50G51_AA A 31 ? A 51 ? A 32 ? A 50 ? 
1 A A 32 1_555 A U 50 1_555 A G 33 1_555 A C 49 1_555 0.124  -1.353 3.303 1.809  22.300 33.173  -4.306 0.006  2.037  34.600 -2.807 
39.836  19 AA_A32G33:C49U50_AA A 32 ? A 50 ? A 33 ? A 49 ? 
1 A G 33 1_555 A C 49 1_555 A G 34 1_555 A U 48 1_555 -0.317 -1.760 4.047 -5.492 3.909  32.010  -3.948 -0.590 3.811  6.991  9.823 
32.694  20 AA_G33G34:U48C49_AA A 33 ? A 49 ? A 34 ? A 48 ? 
1 A G 34 1_555 A U 48 1_555 A G 35 1_555 A C 47 1_555 -0.154 -1.620 3.824 -1.231 2.950  34.470  -3.245 0.042  3.681  4.964  2.072 
34.613  21 AA_G34G35:C47U48_AA A 34 ? A 48 ? A 35 ? A 47 ? 
1 A G 35 1_555 A C 47 1_555 A C 36 1_555 A G 46 1_555 0.467  -1.870 3.184 2.820  2.442  35.885  -3.352 -0.370 3.081  3.951  -4.562 
36.072  22 AA_G35C36:G46C47_AA A 35 ? A 47 ? A 36 ? A 46 ? 
1 A C 36 1_555 A G 46 1_555 A A 37 1_555 A U 45 1_555 0.320  -1.613 4.233 7.041  -0.181 31.113  -2.894 1.093  4.211  -0.332 
-12.920 31.881  23 AA_C36A37:U45G46_AA A 36 ? A 46 ? A 37 ? A 45 ? 
1 A A 37 1_555 A U 45 1_555 A A 38 1_555 A U 44 1_555 0.425  -1.341 3.793 0.998  -0.418 28.226  -2.634 -0.600 3.824  -0.856 -2.046 
28.247  24 AA_A37A38:U44U45_AA A 37 ? A 45 ? A 38 ? A 44 ? 
# 
_pdbx_audit_support.funding_organization   'European Research Council (ERC)' 
_pdbx_audit_support.country                'European Union' 
_pdbx_audit_support.grant_number           950278 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_initial_refinement_model.id 
_pdbx_initial_refinement_model.type 
_pdbx_initial_refinement_model.source_name 
_pdbx_initial_refinement_model.accession_code 
1 'in silico model' AlphaFold AF-Q9BV90-F1 
2 'in silico model' AlphaFold AF-Q16560-F1 
3 'in silico model' AlphaFold AF-Q8N8D1-F1 
# 
_atom_sites.entry_id                    9GCM 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    P P     . U   A 1 11  ? 168.955 168.587 171.316 1.00 150.39 ? 11  U   A P     1 
ATOM 2    O OP1   . U   A 1 11  ? 168.697 169.836 172.075 1.00 146.41 ? 11  U   A OP1   1 
ATOM 3    O OP2   . U   A 1 11  ? 170.240 167.866 171.501 1.00 146.72 ? 11  U   A OP2   1 
ATOM 4    O "O5'" . U   A 1 11  ? 167.774 167.569 171.638 1.00 144.32 ? 11  U   A "O5'" 1 
ATOM 5    C "C5'" . U   A 1 11  ? 166.422 168.000 171.642 1.00 143.10 ? 11  U   A "C5'" 1 
ATOM 6    C "C4'" . U   A 1 11  ? 165.482 166.850 171.387 1.00 142.46 ? 11  U   A "C4'" 1 
ATOM 7    O "O4'" . U   A 1 11  ? 165.806 166.235 170.114 1.00 142.15 ? 11  U   A "O4'" 1 
ATOM 8    C "C3'" . U   A 1 11  ? 165.554 165.701 172.380 1.00 144.06 ? 11  U   A "C3'" 1 
ATOM 9    O "O3'" . U   A 1 11  ? 164.811 165.942 173.562 1.00 146.51 ? 11  U   A "O3'" 1 
ATOM 10   C "C2'" . U   A 1 11  ? 165.032 164.528 171.566 1.00 143.73 ? 11  U   A "C2'" 1 
ATOM 11   O "O2'" . U   A 1 11  ? 163.616 164.572 171.480 1.00 144.27 ? 11  U   A "O2'" 1 
ATOM 12   C "C1'" . U   A 1 11  ? 165.601 164.841 170.187 1.00 141.80 ? 11  U   A "C1'" 1 
ATOM 13   N N1    . U   A 1 11  ? 166.889 164.160 169.936 1.00 140.25 ? 11  U   A N1    1 
ATOM 14   C C2    . U   A 1 11  ? 166.854 162.816 169.632 1.00 142.12 ? 11  U   A C2    1 
ATOM 15   O O2    . U   A 1 11  ? 165.822 162.170 169.578 1.00 145.51 ? 11  U   A O2    1 
ATOM 16   N N3    . U   A 1 11  ? 168.072 162.240 169.395 1.00 139.66 ? 11  U   A N3    1 
ATOM 17   C C4    . U   A 1 11  ? 169.299 162.864 169.428 1.00 139.31 ? 11  U   A C4    1 
ATOM 18   O O4    . U   A 1 11  ? 170.317 162.215 169.193 1.00 140.44 ? 11  U   A O4    1 
ATOM 19   C C5    . U   A 1 11  ? 169.252 164.257 169.745 1.00 140.45 ? 11  U   A C5    1 
ATOM 20   C C6    . U   A 1 11  ? 168.077 164.845 169.980 1.00 140.23 ? 11  U   A C6    1 
ATOM 21   P P     . C   A 1 12  ? 165.183 165.170 174.920 1.00 154.32 ? 12  C   A P     1 
ATOM 22   O OP1   . C   A 1 12  ? 164.460 165.830 176.035 1.00 149.05 ? 12  C   A OP1   1 
ATOM 23   O OP2   . C   A 1 12  ? 166.659 165.027 174.973 1.00 146.59 ? 12  C   A OP2   1 
ATOM 24   O "O5'" . C   A 1 12  ? 164.564 163.716 174.724 1.00 147.10 ? 12  C   A "O5'" 1 
ATOM 25   C "C5'" . C   A 1 12  ? 163.179 163.541 174.447 1.00 144.91 ? 12  C   A "C5'" 1 
ATOM 26   C "C4'" . C   A 1 12  ? 162.907 162.198 173.819 1.00 144.29 ? 12  C   A "C4'" 1 
ATOM 27   O "O4'" . C   A 1 12  ? 164.005 161.865 172.926 1.00 143.71 ? 12  C   A "O4'" 1 
ATOM 28   C "C3'" . C   A 1 12  ? 162.789 161.037 174.801 1.00 147.18 ? 12  C   A "C3'" 1 
ATOM 29   O "O3'" . C   A 1 12  ? 161.835 160.094 174.314 1.00 149.37 ? 12  C   A "O3'" 1 
ATOM 30   C "C2'" . C   A 1 12  ? 164.183 160.423 174.767 1.00 148.22 ? 12  C   A "C2'" 1 
ATOM 31   O "O2'" . C   A 1 12  ? 164.234 159.059 175.120 1.00 148.34 ? 12  C   A "O2'" 1 
ATOM 32   C "C1'" . C   A 1 12  ? 164.577 160.631 173.311 1.00 146.69 ? 12  C   A "C1'" 1 
ATOM 33   N N1    . C   A 1 12  ? 166.028 160.705 173.102 1.00 146.33 ? 12  C   A N1    1 
ATOM 34   C C2    . C   A 1 12  ? 166.705 159.542 172.737 1.00 146.06 ? 12  C   A C2    1 
ATOM 35   O O2    . C   A 1 12  ? 166.058 158.496 172.602 1.00 147.44 ? 12  C   A O2    1 
ATOM 36   N N3    . C   A 1 12  ? 168.040 159.583 172.545 1.00 143.72 ? 12  C   A N3    1 
ATOM 37   C C4    . C   A 1 12  ? 168.692 160.734 172.705 1.00 143.26 ? 12  C   A C4    1 
ATOM 38   N N4    . C   A 1 12  ? 170.009 160.736 172.503 1.00 142.76 ? 12  C   A N4    1 
ATOM 39   C C5    . C   A 1 12  ? 168.025 161.936 173.078 1.00 144.27 ? 12  C   A C5    1 
ATOM 40   C C6    . C   A 1 12  ? 166.703 161.878 173.267 1.00 145.27 ? 12  C   A C6    1 
ATOM 41   P P     . U   A 1 13  ? 160.677 159.549 175.286 1.00 146.91 ? 13  U   A P     1 
ATOM 42   O OP1   . U   A 1 13  ? 160.763 160.295 176.565 1.00 136.77 ? 13  U   A OP1   1 
ATOM 43   O OP2   . U   A 1 13  ? 160.727 158.066 175.293 1.00 137.34 ? 13  U   A OP2   1 
ATOM 44   O "O5'" . U   A 1 13  ? 159.329 159.984 174.563 1.00 139.17 ? 13  U   A "O5'" 1 
ATOM 45   C "C5'" . U   A 1 13  ? 158.365 160.774 175.241 1.00 134.90 ? 13  U   A "C5'" 1 
ATOM 46   C "C4'" . U   A 1 13  ? 156.983 160.198 175.082 1.00 133.05 ? 13  U   A "C4'" 1 
ATOM 47   O "O4'" . U   A 1 13  ? 156.938 158.867 175.654 1.00 131.08 ? 13  U   A "O4'" 1 
ATOM 48   C "C3'" . U   A 1 13  ? 155.863 160.937 175.792 1.00 136.84 ? 13  U   A "C3'" 1 
ATOM 49   O "O3'" . U   A 1 13  ? 155.423 162.082 175.084 1.00 139.30 ? 13  U   A "O3'" 1 
ATOM 50   C "C2'" . U   A 1 13  ? 154.796 159.859 175.932 1.00 136.68 ? 13  U   A "C2'" 1 
ATOM 51   O "O2'" . U   A 1 13  ? 154.095 159.685 174.709 1.00 135.33 ? 13  U   A "O2'" 1 
ATOM 52   C "C1'" . U   A 1 13  ? 155.651 158.614 176.176 1.00 133.59 ? 13  U   A "C1'" 1 
ATOM 53   N N1    . U   A 1 13  ? 155.761 158.282 177.615 1.00 130.74 ? 13  U   A N1    1 
ATOM 54   C C2    . U   A 1 13  ? 154.723 157.556 178.154 1.00 134.11 ? 13  U   A C2    1 
ATOM 55   O O2    . U   A 1 13  ? 153.760 157.199 177.499 1.00 136.63 ? 13  U   A O2    1 
ATOM 56   N N3    . U   A 1 13  ? 154.835 157.257 179.485 1.00 132.99 ? 13  U   A N3    1 
ATOM 57   C C4    . U   A 1 13  ? 155.874 157.606 180.321 1.00 131.77 ? 13  U   A C4    1 
ATOM 58   O O4    . U   A 1 13  ? 155.839 157.263 181.503 1.00 129.45 ? 13  U   A O4    1 
ATOM 59   C C5    . U   A 1 13  ? 156.914 158.358 179.690 1.00 132.78 ? 13  U   A C5    1 
ATOM 60   C C6    . U   A 1 13  ? 156.828 158.665 178.391 1.00 130.62 ? 13  U   A C6    1 
ATOM 61   P P     . G   A 1 14  ? 154.670 163.271 175.858 1.00 137.29 ? 14  G   A P     1 
ATOM 62   O OP1   . G   A 1 14  ? 154.627 164.451 174.961 1.00 128.51 ? 14  G   A OP1   1 
ATOM 63   O OP2   . G   A 1 14  ? 155.269 163.396 177.209 1.00 127.50 ? 14  G   A OP2   1 
ATOM 64   O "O5'" . G   A 1 14  ? 153.181 162.734 176.027 1.00 124.24 ? 14  G   A "O5'" 1 
ATOM 65   C "C5'" . G   A 1 14  ? 152.406 162.380 174.894 1.00 119.93 ? 14  G   A "C5'" 1 
ATOM 66   C "C4'" . G   A 1 14  ? 151.146 161.658 175.292 1.00 121.34 ? 14  G   A "C4'" 1 
ATOM 67   O "O4'" . G   A 1 14  ? 151.474 160.388 175.910 1.00 121.02 ? 14  G   A "O4'" 1 
ATOM 68   C "C3'" . G   A 1 14  ? 150.283 162.354 176.327 1.00 126.28 ? 14  G   A "C3'" 1 
ATOM 69   O "O3'" . G   A 1 14  ? 149.483 163.382 175.773 1.00 128.86 ? 14  G   A "O3'" 1 
ATOM 70   C "C2'" . G   A 1 14  ? 149.482 161.202 176.915 1.00 125.43 ? 14  G   A "C2'" 1 
ATOM 71   O "O2'" . G   A 1 14  ? 148.418 160.840 176.050 1.00 124.62 ? 14  G   A "O2'" 1 
ATOM 72   C "C1'" . G   A 1 14  ? 150.518 160.077 176.902 1.00 124.84 ? 14  G   A "C1'" 1 
ATOM 73   N N9    . G   A 1 14  ? 151.204 159.934 178.202 1.00 125.06 ? 14  G   A N9    1 
ATOM 74   C C8    . G   A 1 14  ? 152.496 160.280 178.510 1.00 123.23 ? 14  G   A C8    1 
ATOM 75   N N7    . G   A 1 14  ? 152.814 160.028 179.750 1.00 117.78 ? 14  G   A N7    1 
ATOM 76   C C5    . G   A 1 14  ? 151.663 159.480 180.293 1.00 114.54 ? 14  G   A C5    1 
ATOM 77   C C6    . G   A 1 14  ? 151.397 159.015 181.602 1.00 118.58 ? 14  G   A C6    1 
ATOM 78   O O6    . G   A 1 14  ? 152.154 158.985 182.577 1.00 123.68 ? 14  G   A O6    1 
ATOM 79   N N1    . G   A 1 14  ? 150.100 158.538 181.723 1.00 119.96 ? 14  G   A N1    1 
ATOM 80   C C2    . G   A 1 14  ? 149.171 158.516 180.716 1.00 121.14 ? 14  G   A C2    1 
ATOM 81   N N2    . G   A 1 14  ? 147.964 158.022 181.018 1.00 122.23 ? 14  G   A N2    1 
ATOM 82   N N3    . G   A 1 14  ? 149.404 158.951 179.493 1.00 121.73 ? 14  G   A N3    1 
ATOM 83   C C4    . G   A 1 14  ? 150.662 159.414 179.353 1.00 118.99 ? 14  G   A C4    1 
ATOM 84   P P     . U   A 1 15  ? 149.146 164.694 176.634 1.00 139.44 ? 15  U   A P     1 
ATOM 85   O OP1   . U   A 1 15  ? 148.539 165.700 175.727 1.00 133.30 ? 15  U   A OP1   1 
ATOM 86   O OP2   . U   A 1 15  ? 150.350 165.052 177.423 1.00 130.59 ? 15  U   A OP2   1 
ATOM 87   O "O5'" . U   A 1 15  ? 148.016 164.203 177.641 1.00 130.61 ? 15  U   A "O5'" 1 
ATOM 88   C "C5'" . U   A 1 15  ? 146.806 163.650 177.151 1.00 129.89 ? 15  U   A "C5'" 1 
ATOM 89   C "C4'" . U   A 1 15  ? 146.025 162.972 178.245 1.00 127.67 ? 15  U   A "C4'" 1 
ATOM 90   O "O4'" . U   A 1 15  ? 146.754 161.815 178.728 1.00 123.94 ? 15  U   A "O4'" 1 
ATOM 91   C "C3'" . U   A 1 15  ? 145.783 163.801 179.494 1.00 131.43 ? 15  U   A "C3'" 1 
ATOM 92   O "O3'" . U   A 1 15  ? 144.705 164.708 179.351 1.00 135.37 ? 15  U   A "O3'" 1 
ATOM 93   C "C2'" . U   A 1 15  ? 145.550 162.736 180.554 1.00 130.55 ? 15  U   A "C2'" 1 
ATOM 94   O "O2'" . U   A 1 15  ? 144.233 162.218 180.463 1.00 127.93 ? 15  U   A "O2'" 1 
ATOM 95   C "C1'" . U   A 1 15  ? 146.530 161.649 180.111 1.00 128.99 ? 15  U   A "C1'" 1 
ATOM 96   N N1    . U   A 1 15  ? 147.829 161.748 180.814 1.00 131.48 ? 15  U   A N1    1 
ATOM 97   C C2    . U   A 1 15  ? 147.885 161.328 182.128 1.00 131.50 ? 15  U   A C2    1 
ATOM 98   O O2    . U   A 1 15  ? 146.922 160.888 182.729 1.00 132.24 ? 15  U   A O2    1 
ATOM 99   N N3    . U   A 1 15  ? 149.114 161.448 182.721 1.00 126.81 ? 15  U   A N3    1 
ATOM 100  C C4    . U   A 1 15  ? 150.268 161.932 182.149 1.00 124.90 ? 15  U   A C4    1 
ATOM 101  O O4    . U   A 1 15  ? 151.299 161.973 182.818 1.00 127.09 ? 15  U   A O4    1 
ATOM 102  C C5    . U   A 1 15  ? 150.131 162.344 180.788 1.00 124.10 ? 15  U   A C5    1 
ATOM 103  C C6    . U   A 1 15  ? 148.945 162.239 180.184 1.00 126.32 ? 15  U   A C6    1 
ATOM 104  P P     . C   A 1 16  ? 144.729 166.118 180.119 1.00 144.34 ? 16  C   A P     1 
ATOM 105  O OP1   . C   A 1 16  ? 143.681 166.985 179.527 1.00 137.96 ? 16  C   A OP1   1 
ATOM 106  O OP2   . C   A 1 16  ? 146.133 166.595 180.165 1.00 130.55 ? 16  C   A OP2   1 
ATOM 107  O "O5'" . C   A 1 16  ? 144.271 165.751 181.598 1.00 135.16 ? 16  C   A "O5'" 1 
ATOM 108  C "C5'" . C   A 1 16  ? 143.002 165.163 181.836 1.00 131.20 ? 16  C   A "C5'" 1 
ATOM 109  C "C4'" . C   A 1 16  ? 142.908 164.590 183.227 1.00 129.17 ? 16  C   A "C4'" 1 
ATOM 110  O "O4'" . C   A 1 16  ? 143.858 163.504 183.379 1.00 127.74 ? 16  C   A "O4'" 1 
ATOM 111  C "C3'" . C   A 1 16  ? 143.250 165.538 184.363 1.00 129.91 ? 16  C   A "C3'" 1 
ATOM 112  O "O3'" . C   A 1 16  ? 142.184 166.406 184.703 1.00 132.11 ? 16  C   A "O3'" 1 
ATOM 113  C "C2'" . C   A 1 16  ? 143.640 164.584 185.481 1.00 131.00 ? 16  C   A "C2'" 1 
ATOM 114  O "O2'" . C   A 1 16  ? 142.485 164.025 186.087 1.00 131.93 ? 16  C   A "O2'" 1 
ATOM 115  C "C1'" . C   A 1 16  ? 144.355 163.482 184.700 1.00 128.35 ? 16  C   A "C1'" 1 
ATOM 116  N N1    . C   A 1 16  ? 145.814 163.708 184.657 1.00 127.52 ? 16  C   A N1    1 
ATOM 117  C C2    . C   A 1 16  ? 146.565 163.458 185.804 1.00 128.34 ? 16  C   A C2    1 
ATOM 118  O O2    . C   A 1 16  ? 145.986 163.049 186.821 1.00 126.22 ? 16  C   A O2    1 
ATOM 119  N N3    . C   A 1 16  ? 147.897 163.671 185.770 1.00 131.05 ? 16  C   A N3    1 
ATOM 120  C C4    . C   A 1 16  ? 148.476 164.112 184.652 1.00 130.88 ? 16  C   A C4    1 
ATOM 121  N N4    . C   A 1 16  ? 149.793 164.310 184.660 1.00 132.28 ? 16  C   A N4    1 
ATOM 122  C C5    . C   A 1 16  ? 147.734 164.377 183.471 1.00 129.98 ? 16  C   A C5    1 
ATOM 123  C C6    . C   A 1 16  ? 146.418 164.163 183.522 1.00 130.20 ? 16  C   A C6    1 
ATOM 124  P P     . G   A 1 17  ? 142.473 167.743 185.544 1.00 128.46 ? 17  G   A P     1 
ATOM 125  O OP1   . G   A 1 17  ? 141.220 168.534 185.616 1.00 128.47 ? 17  G   A OP1   1 
ATOM 126  O OP2   . G   A 1 17  ? 143.703 168.364 184.994 1.00 123.18 ? 17  G   A OP2   1 
ATOM 127  O "O5'" . G   A 1 17  ? 142.796 167.209 187.009 1.00 129.01 ? 17  G   A "O5'" 1 
ATOM 128  C "C5'" . G   A 1 17  ? 143.493 168.019 187.941 1.00 128.06 ? 17  G   A "C5'" 1 
ATOM 129  C "C4'" . G   A 1 17  ? 144.288 167.186 188.914 1.00 124.70 ? 17  G   A "C4'" 1 
ATOM 130  O "O4'" . G   A 1 17  ? 145.030 166.165 188.198 1.00 123.21 ? 17  G   A "O4'" 1 
ATOM 131  C "C3'" . G   A 1 17  ? 145.346 167.935 189.706 1.00 126.06 ? 17  G   A "C3'" 1 
ATOM 132  O "O3'" . G   A 1 17  ? 144.810 168.591 190.840 1.00 131.59 ? 17  G   A "O3'" 1 
ATOM 133  C "C2'" . G   A 1 17  ? 146.344 166.840 190.053 1.00 125.17 ? 17  G   A "C2'" 1 
ATOM 134  O "O2'" . G   A 1 17  ? 145.875 166.069 191.148 1.00 128.30 ? 17  G   A "O2'" 1 
ATOM 135  C "C1'" . G   A 1 17  ? 146.291 165.972 188.797 1.00 120.72 ? 17  G   A "C1'" 1 
ATOM 136  N N9    . G   A 1 17  ? 147.321 166.347 187.810 1.00 120.66 ? 17  G   A N9    1 
ATOM 137  C C8    . G   A 1 17  ? 147.069 166.675 186.503 1.00 124.71 ? 17  G   A C8    1 
ATOM 138  N N7    . G   A 1 17  ? 148.142 166.965 185.827 1.00 124.12 ? 17  G   A N7    1 
ATOM 139  C C5    . G   A 1 17  ? 149.170 166.814 186.743 1.00 128.10 ? 17  G   A C5    1 
ATOM 140  C C6    . G   A 1 17  ? 150.564 166.994 186.574 1.00 128.61 ? 17  G   A C6    1 
ATOM 141  O O6    . G   A 1 17  ? 151.180 167.333 185.558 1.00 128.22 ? 17  G   A O6    1 
ATOM 142  N N1    . G   A 1 17  ? 151.259 166.742 187.749 1.00 125.86 ? 17  G   A N1    1 
ATOM 143  C C2    . G   A 1 17  ? 150.687 166.366 188.934 1.00 125.84 ? 17  G   A C2    1 
ATOM 144  N N2    . G   A 1 17  ? 151.538 166.171 189.949 1.00 123.46 ? 17  G   A N2    1 
ATOM 145  N N3    . G   A 1 17  ? 149.386 166.188 189.107 1.00 128.39 ? 17  G   A N3    1 
ATOM 146  C C4    . G   A 1 17  ? 148.686 166.428 187.976 1.00 126.49 ? 17  G   A C4    1 
ATOM 147  P P     . U   A 1 18  ? 144.782 170.195 190.913 1.00 141.69 ? 18  U   A P     1 
ATOM 148  O OP1   . U   A 1 18  ? 143.516 170.601 191.572 1.00 132.62 ? 18  U   A OP1   1 
ATOM 149  O OP2   . U   A 1 18  ? 145.109 170.722 189.565 1.00 131.04 ? 18  U   A OP2   1 
ATOM 150  O "O5'" . U   A 1 18  ? 145.985 170.556 191.893 1.00 134.55 ? 18  U   A "O5'" 1 
ATOM 151  C "C5'" . U   A 1 18  ? 145.993 170.092 193.239 1.00 132.78 ? 18  U   A "C5'" 1 
ATOM 152  C "C4'" . U   A 1 18  ? 147.282 170.428 193.950 1.00 128.31 ? 18  U   A "C4'" 1 
ATOM 153  O "O4'" . U   A 1 18  ? 148.389 169.766 193.280 1.00 124.77 ? 18  U   A "O4'" 1 
ATOM 154  C "C3'" . U   A 1 18  ? 147.637 171.913 193.993 1.00 129.38 ? 18  U   A "C3'" 1 
ATOM 155  O "O3'" . U   A 1 18  ? 148.342 172.195 195.201 1.00 133.48 ? 18  U   A "O3'" 1 
ATOM 156  C "C2'" . U   A 1 18  ? 148.601 172.053 192.821 1.00 131.12 ? 18  U   A "C2'" 1 
ATOM 157  O "O2'" . U   A 1 18  ? 149.478 173.155 192.910 1.00 133.25 ? 18  U   A "O2'" 1 
ATOM 158  C "C1'" . U   A 1 18  ? 149.349 170.727 192.892 1.00 128.38 ? 18  U   A "C1'" 1 
ATOM 159  N N1    . U   A 1 18  ? 149.939 170.304 191.618 1.00 126.33 ? 18  U   A N1    1 
ATOM 160  C C2    . U   A 1 18  ? 151.300 170.453 191.477 1.00 130.42 ? 18  U   A C2    1 
ATOM 161  O O2    . U   A 1 18  ? 152.005 170.916 192.353 1.00 134.87 ? 18  U   A O2    1 
ATOM 162  N N3    . U   A 1 18  ? 151.807 170.047 190.273 1.00 127.79 ? 18  U   A N3    1 
ATOM 163  C C4    . U   A 1 18  ? 151.098 169.517 189.221 1.00 127.05 ? 18  U   A C4    1 
ATOM 164  O O4    . U   A 1 18  ? 151.700 169.196 188.197 1.00 128.77 ? 18  U   A O4    1 
ATOM 165  C C5    . U   A 1 18  ? 149.691 169.395 189.446 1.00 128.21 ? 18  U   A C5    1 
ATOM 166  C C6    . U   A 1 18  ? 149.169 169.781 190.611 1.00 124.94 ? 18  U   A C6    1 
ATOM 167  P P     . G   A 1 19  ? 147.561 172.471 196.578 1.00 130.12 ? 19  G   A P     1 
ATOM 168  O OP1   . G   A 1 19  ? 146.334 171.638 196.636 1.00 109.23 ? 19  G   A OP1   1 
ATOM 169  O OP2   . G   A 1 19  ? 147.461 173.940 196.756 1.00 124.10 ? 19  G   A OP2   1 
ATOM 170  O "O5'" . G   A 1 19  ? 148.568 171.914 197.678 1.00 119.00 ? 19  G   A "O5'" 1 
ATOM 171  C "C5'" . G   A 1 19  ? 149.263 170.694 197.453 1.00 113.31 ? 19  G   A "C5'" 1 
ATOM 172  C "C4'" . G   A 1 19  ? 150.682 170.747 197.961 1.00 106.98 ? 19  G   A "C4'" 1 
ATOM 173  O "O4'" . G   A 1 19  ? 150.660 170.741 199.412 1.00 107.83 ? 19  G   A "O4'" 1 
ATOM 174  C "C3'" . G   A 1 19  ? 151.547 169.562 197.550 1.00 106.05 ? 19  G   A "C3'" 1 
ATOM 175  O "O3'" . G   A 1 19  ? 152.907 169.980 197.449 1.00 107.69 ? 19  G   A "O3'" 1 
ATOM 176  C "C2'" . G   A 1 19  ? 151.399 168.623 198.737 1.00 107.42 ? 19  G   A "C2'" 1 
ATOM 177  O "O2'" . G   A 1 19  ? 152.443 167.685 198.878 1.00 110.41 ? 19  G   A "O2'" 1 
ATOM 178  C "C1'" . G   A 1 19  ? 151.363 169.612 199.894 1.00 110.39 ? 19  G   A "C1'" 1 
ATOM 179  N N9    . G   A 1 19  ? 150.670 169.115 201.081 1.00 108.40 ? 19  G   A N9    1 
ATOM 180  C C8    . G   A 1 19  ? 149.456 168.482 201.129 1.00 111.59 ? 19  G   A C8    1 
ATOM 181  N N7    . G   A 1 19  ? 149.100 168.162 202.342 1.00 110.37 ? 19  G   A N7    1 
ATOM 182  C C5    . G   A 1 19  ? 150.143 168.613 203.135 1.00 104.89 ? 19  G   A C5    1 
ATOM 183  C C6    . G   A 1 19  ? 150.323 168.547 204.536 1.00 110.44 ? 19  G   A C6    1 
ATOM 184  O O6    . G   A 1 19  ? 149.568 168.060 205.384 1.00 112.20 ? 19  G   A O6    1 
ATOM 185  N N1    . G   A 1 19  ? 151.526 169.126 204.922 1.00 109.47 ? 19  G   A N1    1 
ATOM 186  C C2    . G   A 1 19  ? 152.439 169.693 204.072 1.00 104.84 ? 19  G   A C2    1 
ATOM 187  N N2    . G   A 1 19  ? 153.543 170.201 204.635 1.00 105.19 ? 19  G   A N2    1 
ATOM 188  N N3    . G   A 1 19  ? 152.282 169.760 202.765 1.00 108.03 ? 19  G   A N3    1 
ATOM 189  C C4    . G   A 1 19  ? 151.118 169.207 202.372 1.00 105.94 ? 19  G   A C4    1 
ATOM 190  P P     . A   A 1 20  ? 153.504 170.467 196.041 1.00 119.66 ? 20  A   A P     1 
ATOM 191  O OP1   . A   A 1 20  ? 154.375 171.640 196.297 1.00 116.87 ? 20  A   A OP1   1 
ATOM 192  O OP2   . A   A 1 20  ? 152.375 170.593 195.091 1.00 121.24 ? 20  A   A OP2   1 
ATOM 193  O "O5'" . A   A 1 20  ? 154.428 169.258 195.567 1.00 114.75 ? 20  A   A "O5'" 1 
ATOM 194  C "C5'" . A   A 1 20  ? 154.249 167.955 196.097 1.00 112.29 ? 20  A   A "C5'" 1 
ATOM 195  C "C4'" . A   A 1 20  ? 154.206 166.910 195.013 1.00 111.71 ? 20  A   A "C4'" 1 
ATOM 196  O "O4'" . A   A 1 20  ? 153.094 166.009 195.248 1.00 110.18 ? 20  A   A "O4'" 1 
ATOM 197  C "C3'" . A   A 1 20  ? 153.969 167.417 193.602 1.00 117.42 ? 20  A   A "C3'" 1 
ATOM 198  O "O3'" . A   A 1 20  ? 155.144 167.919 192.996 1.00 119.64 ? 20  A   A "O3'" 1 
ATOM 199  C "C2'" . A   A 1 20  ? 153.402 166.191 192.905 1.00 116.21 ? 20  A   A "C2'" 1 
ATOM 200  O "O2'" . A   A 1 20  ? 154.437 165.273 192.593 1.00 118.82 ? 20  A   A "O2'" 1 
ATOM 201  C "C1'" . A   A 1 20  ? 152.548 165.587 194.017 1.00 113.54 ? 20  A   A "C1'" 1 
ATOM 202  N N9    . A   A 1 20  ? 151.149 166.047 193.933 1.00 116.03 ? 20  A   A N9    1 
ATOM 203  C C8    . A   A 1 20  ? 150.447 166.342 192.792 1.00 113.88 ? 20  A   A C8    1 
ATOM 204  N N7    . A   A 1 20  ? 149.212 166.720 193.003 1.00 109.24 ? 20  A   A N7    1 
ATOM 205  C C5    . A   A 1 20  ? 149.089 166.664 194.380 1.00 111.15 ? 20  A   A C5    1 
ATOM 206  C C6    . A   A 1 20  ? 148.016 166.946 195.239 1.00 112.43 ? 20  A   A C6    1 
ATOM 207  N N6    . A   A 1 20  ? 146.819 167.352 194.818 1.00 114.77 ? 20  A   A N6    1 
ATOM 208  N N1    . A   A 1 20  ? 148.211 166.791 196.564 1.00 115.11 ? 20  A   A N1    1 
ATOM 209  C C2    . A   A 1 20  ? 149.411 166.383 196.987 1.00 119.01 ? 20  A   A C2    1 
ATOM 210  N N3    . A   A 1 20  ? 150.496 166.085 196.280 1.00 121.18 ? 20  A   A N3    1 
ATOM 211  C C4    . A   A 1 20  ? 150.268 166.245 194.967 1.00 116.72 ? 20  A   A C4    1 
ATOM 212  P P     . G   A 1 21  ? 155.050 169.090 191.903 1.00 125.77 ? 21  G   A P     1 
ATOM 213  O OP1   . G   A 1 21  ? 154.715 170.360 192.593 1.00 120.49 ? 21  G   A OP1   1 
ATOM 214  O OP2   . G   A 1 21  ? 154.200 168.604 190.788 1.00 114.55 ? 21  G   A OP2   1 
ATOM 215  O "O5'" . G   A 1 21  ? 156.540 169.214 191.363 1.00 112.43 ? 21  G   A "O5'" 1 
ATOM 216  C "C5'" . G   A 1 21  ? 157.209 168.080 190.840 1.00 110.71 ? 21  G   A "C5'" 1 
ATOM 217  C "C4'" . G   A 1 21  ? 157.789 168.374 189.485 1.00 110.09 ? 21  G   A "C4'" 1 
ATOM 218  O "O4'" . G   A 1 21  ? 158.927 169.259 189.617 1.00 111.95 ? 21  G   A "O4'" 1 
ATOM 219  C "C3'" . G   A 1 21  ? 158.346 167.190 188.719 1.00 111.97 ? 21  G   A "C3'" 1 
ATOM 220  O "O3'" . G   A 1 21  ? 157.339 166.402 188.112 1.00 119.05 ? 21  G   A "O3'" 1 
ATOM 221  C "C2'" . G   A 1 21  ? 159.282 167.863 187.725 1.00 108.84 ? 21  G   A "C2'" 1 
ATOM 222  O "O2'" . G   A 1 21  ? 158.547 168.421 186.647 1.00 111.89 ? 21  G   A "O2'" 1 
ATOM 223  C "C1'" . G   A 1 21  ? 159.840 169.011 188.571 1.00 108.43 ? 21  G   A "C1'" 1 
ATOM 224  N N9    . G   A 1 21  ? 161.189 168.742 189.125 1.00 111.63 ? 21  G   A N9    1 
ATOM 225  C C8    . G   A 1 21  ? 162.021 169.742 189.561 1.00 111.23 ? 21  G   A C8    1 
ATOM 226  N N7    . G   A 1 21  ? 163.171 169.323 189.998 1.00 106.50 ? 21  G   A N7    1 
ATOM 227  C C5    . G   A 1 21  ? 163.112 167.952 189.844 1.00 108.37 ? 21  G   A C5    1 
ATOM 228  C C6    . G   A 1 21  ? 164.090 166.976 190.158 1.00 110.15 ? 21  G   A C6    1 
ATOM 229  O O6    . G   A 1 21  ? 165.214 167.141 190.640 1.00 113.42 ? 21  G   A O6    1 
ATOM 230  N N1    . G   A 1 21  ? 163.658 165.694 189.859 1.00 111.45 ? 21  G   A N1    1 
ATOM 231  C C2    . G   A 1 21  ? 162.438 165.393 189.323 1.00 113.53 ? 21  G   A C2    1 
ATOM 232  N N2    . G   A 1 21  ? 162.200 164.093 189.100 1.00 111.83 ? 21  G   A N2    1 
ATOM 233  N N3    . G   A 1 21  ? 161.519 166.296 189.028 1.00 114.87 ? 21  G   A N3    1 
ATOM 234  C C4    . G   A 1 21  ? 161.901 167.563 189.308 1.00 112.60 ? 21  G   A C4    1 
ATOM 235  P P     . U   A 1 22  ? 157.550 164.819 187.940 1.00 118.52 ? 22  U   A P     1 
ATOM 236  O OP1   . U   A 1 22  ? 158.728 164.598 187.066 1.00 109.59 ? 22  U   A OP1   1 
ATOM 237  O OP2   . U   A 1 22  ? 156.242 164.221 187.581 1.00 102.38 ? 22  U   A OP2   1 
ATOM 238  O "O5'" . U   A 1 22  ? 157.930 164.311 189.400 1.00 112.96 ? 22  U   A "O5'" 1 
ATOM 239  C "C5'" . U   A 1 22  ? 158.537 163.036 189.580 1.00 110.66 ? 22  U   A "C5'" 1 
ATOM 240  C "C4'" . U   A 1 22  ? 158.486 162.566 191.014 1.00 107.79 ? 22  U   A "C4'" 1 
ATOM 241  O "O4'" . U   A 1 22  ? 159.421 163.333 191.822 1.00 109.98 ? 22  U   A "O4'" 1 
ATOM 242  C "C3'" . U   A 1 22  ? 157.130 162.677 191.709 1.00 101.84 ? 22  U   A "C3'" 1 
ATOM 243  O "O3'" . U   A 1 22  ? 156.965 161.559 192.578 1.00 101.89 ? 22  U   A "O3'" 1 
ATOM 244  C "C2'" . U   A 1 22  ? 157.291 163.937 192.552 1.00 101.07 ? 22  U   A "C2'" 1 
ATOM 245  O "O2'" . U   A 1 22  ? 156.434 164.009 193.670 1.00 98.71  ? 22  U   A "O2'" 1 
ATOM 246  C "C1'" . U   A 1 22  ? 158.754 163.831 192.960 1.00 106.37 ? 22  U   A "C1'" 1 
ATOM 247  N N1    . U   A 1 22  ? 159.372 165.102 193.355 1.00 107.62 ? 22  U   A N1    1 
ATOM 248  C C2    . U   A 1 22  ? 160.684 165.053 193.767 1.00 104.13 ? 22  U   A C2    1 
ATOM 249  O O2    . U   A 1 22  ? 161.329 164.020 193.778 1.00 104.79 ? 22  U   A O2    1 
ATOM 250  N N3    . U   A 1 22  ? 161.218 166.257 194.140 1.00 102.31 ? 22  U   A N3    1 
ATOM 251  C C4    . U   A 1 22  ? 160.575 167.473 194.159 1.00 99.02  ? 22  U   A C4    1 
ATOM 252  O O4    . U   A 1 22  ? 161.188 168.471 194.526 1.00 105.15 ? 22  U   A O4    1 
ATOM 253  C C5    . U   A 1 22  ? 159.214 167.438 193.735 1.00 101.12 ? 22  U   A C5    1 
ATOM 254  C C6    . U   A 1 22  ? 158.669 166.279 193.363 1.00 106.27 ? 22  U   A C6    1 
ATOM 255  P P     . G   A 1 23  ? 156.266 160.215 192.048 1.00 103.79 ? 23  G   A P     1 
ATOM 256  O OP1   . G   A 1 23  ? 156.777 159.078 192.850 1.00 100.69 ? 23  G   A OP1   1 
ATOM 257  O OP2   . G   A 1 23  ? 156.404 160.170 190.573 1.00 110.97 ? 23  G   A OP2   1 
ATOM 258  O "O5'" . G   A 1 23  ? 154.729 160.430 192.402 1.00 108.20 ? 23  G   A "O5'" 1 
ATOM 259  C "C5'" . G   A 1 23  ? 154.307 160.548 193.751 1.00 109.13 ? 23  G   A "C5'" 1 
ATOM 260  C "C4'" . G   A 1 23  ? 152.809 160.655 193.858 1.00 104.95 ? 23  G   A "C4'" 1 
ATOM 261  O "O4'" . G   A 1 23  ? 152.382 162.000 193.521 1.00 101.34 ? 23  G   A "O4'" 1 
ATOM 262  C "C3'" . G   A 1 23  ? 152.013 159.764 192.921 1.00 104.33 ? 23  G   A "C3'" 1 
ATOM 263  O "O3'" . G   A 1 23  ? 151.885 158.440 193.409 1.00 104.36 ? 23  G   A "O3'" 1 
ATOM 264  C "C2'" . G   A 1 23  ? 150.688 160.502 192.808 1.00 108.21 ? 23  G   A "C2'" 1 
ATOM 265  O "O2'" . G   A 1 23  ? 149.893 160.273 193.961 1.00 106.40 ? 23  G   A "O2'" 1 
ATOM 266  C "C1'" . G   A 1 23  ? 151.153 161.958 192.832 1.00 101.31 ? 23  G   A "C1'" 1 
ATOM 267  N N9    . G   A 1 23  ? 151.381 162.501 191.481 1.00 102.00 ? 23  G   A N9    1 
ATOM 268  C C8    . G   A 1 23  ? 152.570 163.037 191.059 1.00 106.78 ? 23  G   A C8    1 
ATOM 269  N N7    . G   A 1 23  ? 152.539 163.461 189.831 1.00 110.58 ? 23  G   A N7    1 
ATOM 270  C C5    . G   A 1 23  ? 151.250 163.187 189.412 1.00 103.58 ? 23  G   A C5    1 
ATOM 271  C C6    . G   A 1 23  ? 150.652 163.429 188.157 1.00 99.86  ? 23  G   A C6    1 
ATOM 272  O O6    . G   A 1 23  ? 151.165 163.951 187.163 1.00 98.51  ? 23  G   A O6    1 
ATOM 273  N N1    . G   A 1 23  ? 149.334 163.014 188.140 1.00 102.80 ? 23  G   A N1    1 
ATOM 274  C C2    . G   A 1 23  ? 148.669 162.437 189.191 1.00 107.03 ? 23  G   A C2    1 
ATOM 275  N N2    . G   A 1 23  ? 147.396 162.092 188.969 1.00 107.82 ? 23  G   A N2    1 
ATOM 276  N N3    . G   A 1 23  ? 149.222 162.198 190.371 1.00 104.99 ? 23  G   A N3    1 
ATOM 277  C C4    . G   A 1 23  ? 150.511 162.599 190.416 1.00 103.86 ? 23  G   A C4    1 
ATOM 278  P P     . G   A 1 24  ? 152.031 157.188 192.415 1.00 114.39 ? 24  G   A P     1 
ATOM 279  O OP1   . G   A 1 24  ? 152.316 155.973 193.214 1.00 114.07 ? 24  G   A OP1   1 
ATOM 280  O OP2   . G   A 1 24  ? 152.961 157.570 191.328 1.00 114.21 ? 24  G   A OP2   1 
ATOM 281  O "O5'" . G   A 1 24  ? 150.578 157.035 191.786 1.00 121.64 ? 24  G   A "O5'" 1 
ATOM 282  C "C5'" . G   A 1 24  ? 149.427 156.980 192.614 1.00 117.05 ? 24  G   A "C5'" 1 
ATOM 283  C "C4'" . G   A 1 24  ? 148.162 156.986 191.793 1.00 112.52 ? 24  G   A "C4'" 1 
ATOM 284  O "O4'" . G   A 1 24  ? 147.925 158.313 191.262 1.00 109.52 ? 24  G   A "O4'" 1 
ATOM 285  C "C3'" . G   A 1 24  ? 148.168 156.087 190.568 1.00 115.92 ? 24  G   A "C3'" 1 
ATOM 286  O "O3'" . G   A 1 24  ? 147.862 154.742 190.887 1.00 115.32 ? 24  G   A "O3'" 1 
ATOM 287  C "C2'" . G   A 1 24  ? 147.136 156.742 189.661 1.00 119.57 ? 24  G   A "C2'" 1 
ATOM 288  O "O2'" . G   A 1 24  ? 145.824 156.366 190.047 1.00 117.63 ? 24  G   A "O2'" 1 
ATOM 289  C "C1'" . G   A 1 24  ? 147.332 158.224 189.985 1.00 115.52 ? 24  G   A "C1'" 1 
ATOM 290  N N9    . G   A 1 24  ? 148.205 158.911 189.013 1.00 113.95 ? 24  G   A N9    1 
ATOM 291  C C8    . G   A 1 24  ? 149.465 159.391 189.259 1.00 115.33 ? 24  G   A C8    1 
ATOM 292  N N7    . G   A 1 24  ? 150.011 159.967 188.226 1.00 116.27 ? 24  G   A N7    1 
ATOM 293  C C5    . G   A 1 24  ? 149.052 159.864 187.232 1.00 115.70 ? 24  G   A C5    1 
ATOM 294  C C6    . G   A 1 24  ? 149.084 160.308 185.887 1.00 116.39 ? 24  G   A C6    1 
ATOM 295  O O6    . G   A 1 24  ? 149.994 160.899 185.296 1.00 116.57 ? 24  G   A O6    1 
ATOM 296  N N1    . G   A 1 24  ? 147.909 159.998 185.219 1.00 110.40 ? 24  G   A N1    1 
ATOM 297  C C2    . G   A 1 24  ? 146.840 159.345 185.774 1.00 110.92 ? 24  G   A C2    1 
ATOM 298  N N2    . G   A 1 24  ? 145.794 159.138 184.964 1.00 114.63 ? 24  G   A N2    1 
ATOM 299  N N3    . G   A 1 24  ? 146.796 158.924 187.027 1.00 113.37 ? 24  G   A N3    1 
ATOM 300  C C4    . G   A 1 24  ? 147.929 159.217 187.699 1.00 113.52 ? 24  G   A C4    1 
ATOM 301  P P     . C   A 1 25  ? 148.540 153.539 190.069 1.00 117.58 ? 25  C   A P     1 
ATOM 302  O OP1   . C   A 1 25  ? 148.156 152.263 190.717 1.00 115.30 ? 25  C   A OP1   1 
ATOM 303  O OP2   . C   A 1 25  ? 149.975 153.859 189.883 1.00 113.45 ? 25  C   A OP2   1 
ATOM 304  O "O5'" . C   A 1 25  ? 147.831 153.599 188.647 1.00 121.95 ? 25  C   A "O5'" 1 
ATOM 305  C "C5'" . C   A 1 25  ? 146.424 153.448 188.523 1.00 117.42 ? 25  C   A "C5'" 1 
ATOM 306  C "C4'" . C   A 1 25  ? 145.967 153.747 187.119 1.00 115.89 ? 25  C   A "C4'" 1 
ATOM 307  O "O4'" . C   A 1 25  ? 146.118 155.163 186.844 1.00 114.83 ? 25  C   A "O4'" 1 
ATOM 308  C "C3'" . C   A 1 25  ? 146.758 153.069 186.014 1.00 117.34 ? 25  C   A "C3'" 1 
ATOM 309  O "O3'" . C   A 1 25  ? 146.352 151.732 185.787 1.00 120.07 ? 25  C   A "O3'" 1 
ATOM 310  C "C2'" . C   A 1 25  ? 146.525 153.985 184.823 1.00 114.96 ? 25  C   A "C2'" 1 
ATOM 311  O "O2'" . C   A 1 25  ? 145.256 153.733 184.241 1.00 115.41 ? 25  C   A "O2'" 1 
ATOM 312  C "C1'" . C   A 1 25  ? 146.485 155.356 185.495 1.00 111.19 ? 25  C   A "C1'" 1 
ATOM 313  N N1    . C   A 1 25  ? 147.793 156.049 185.451 1.00 111.19 ? 25  C   A N1    1 
ATOM 314  C C2    . C   A 1 25  ? 148.219 156.624 184.254 1.00 114.31 ? 25  C   A C2    1 
ATOM 315  O O2    . C   A 1 25  ? 147.497 156.523 183.253 1.00 117.86 ? 25  C   A O2    1 
ATOM 316  N N3    . C   A 1 25  ? 149.409 157.261 184.214 1.00 113.92 ? 25  C   A N3    1 
ATOM 317  C C4    . C   A 1 25  ? 150.159 157.343 185.310 1.00 110.95 ? 25  C   A C4    1 
ATOM 318  N N4    . C   A 1 25  ? 151.324 157.985 185.227 1.00 114.11 ? 25  C   A N4    1 
ATOM 319  C C5    . C   A 1 25  ? 149.751 156.774 186.545 1.00 109.94 ? 25  C   A C5    1 
ATOM 320  C C6    . C   A 1 25  ? 148.571 156.147 186.568 1.00 115.62 ? 25  C   A C6    1 
ATOM 321  P P     . A   A 1 26  ? 147.413 150.646 185.268 1.00 130.92 ? 26  A   A P     1 
ATOM 322  O OP1   . A   A 1 26  ? 146.761 149.314 185.304 1.00 121.75 ? 26  A   A OP1   1 
ATOM 323  O OP2   . A   A 1 26  ? 148.685 150.860 186.001 1.00 122.37 ? 26  A   A OP2   1 
ATOM 324  O "O5'" . A   A 1 26  ? 147.647 151.038 183.743 1.00 127.97 ? 26  A   A "O5'" 1 
ATOM 325  C "C5'" . A   A 1 26  ? 146.569 151.028 182.821 1.00 126.97 ? 26  A   A "C5'" 1 
ATOM 326  C "C4'" . A   A 1 26  ? 146.894 151.801 181.567 1.00 126.92 ? 26  A   A "C4'" 1 
ATOM 327  O "O4'" . A   A 1 26  ? 147.175 153.185 181.889 1.00 126.81 ? 26  A   A "O4'" 1 
ATOM 328  C "C3'" . A   A 1 26  ? 148.122 151.349 180.800 1.00 124.92 ? 26  A   A "C3'" 1 
ATOM 329  O "O3'" . A   A 1 26  ? 147.871 150.214 179.993 1.00 128.61 ? 26  A   A "O3'" 1 
ATOM 330  C "C2'" . A   A 1 26  ? 148.487 152.591 179.999 1.00 121.49 ? 26  A   A "C2'" 1 
ATOM 331  O "O2'" . A   A 1 26  ? 147.663 152.705 178.850 1.00 123.40 ? 26  A   A "O2'" 1 
ATOM 332  C "C1'" . A   A 1 26  ? 148.114 153.708 180.974 1.00 120.42 ? 26  A   A "C1'" 1 
ATOM 333  N N9    . A   A 1 26  ? 149.285 154.217 181.711 1.00 119.51 ? 26  A   A N9    1 
ATOM 334  C C8    . A   A 1 26  ? 149.602 154.065 183.036 1.00 122.83 ? 26  A   A C8    1 
ATOM 335  N N7    . A   A 1 26  ? 150.724 154.653 183.379 1.00 121.07 ? 26  A   A N7    1 
ATOM 336  C C5    . A   A 1 26  ? 151.174 155.228 182.199 1.00 121.44 ? 26  A   A C5    1 
ATOM 337  C C6    . A   A 1 26  ? 152.311 155.989 181.884 1.00 122.22 ? 26  A   A C6    1 
ATOM 338  N N6    . A   A 1 26  ? 153.252 156.329 182.766 1.00 124.20 ? 26  A   A N6    1 
ATOM 339  N N1    . A   A 1 26  ? 152.456 156.401 180.609 1.00 120.11 ? 26  A   A N1    1 
ATOM 340  C C2    . A   A 1 26  ? 151.516 156.071 179.720 1.00 121.08 ? 26  A   A C2    1 
ATOM 341  N N3    . A   A 1 26  ? 150.410 155.360 179.891 1.00 122.79 ? 26  A   A N3    1 
ATOM 342  C C4    . A   A 1 26  ? 150.296 154.965 181.168 1.00 120.80 ? 26  A   A C4    1 
ATOM 343  P P     . C   A 1 27  ? 149.035 149.144 179.725 1.00 133.23 ? 27  C   A P     1 
ATOM 344  O OP1   . C   A 1 27  ? 148.477 148.030 178.920 1.00 127.55 ? 27  C   A OP1   1 
ATOM 345  O OP2   . C   A 1 27  ? 149.686 148.852 181.026 1.00 126.04 ? 27  C   A OP2   1 
ATOM 346  O "O5'" . C   A 1 27  ? 150.074 149.933 178.813 1.00 123.17 ? 27  C   A "O5'" 1 
ATOM 347  C "C5'" . C   A 1 27  ? 149.680 150.477 177.562 1.00 122.91 ? 27  C   A "C5'" 1 
ATOM 348  C "C4'" . C   A 1 27  ? 150.746 151.379 176.998 1.00 124.16 ? 27  C   A "C4'" 1 
ATOM 349  O "O4'" . C   A 1 27  ? 150.888 152.565 177.820 1.00 123.36 ? 27  C   A "O4'" 1 
ATOM 350  C "C3'" . C   A 1 27  ? 152.141 150.786 176.960 1.00 124.97 ? 27  C   A "C3'" 1 
ATOM 351  O "O3'" . C   A 1 27  ? 152.329 149.936 175.848 1.00 128.04 ? 27  C   A "O3'" 1 
ATOM 352  C "C2'" . C   A 1 27  ? 153.032 152.021 176.950 1.00 122.15 ? 27  C   A "C2'" 1 
ATOM 353  O "O2'" . C   A 1 27  ? 153.105 152.574 175.645 1.00 121.89 ? 27  C   A "O2'" 1 
ATOM 354  C "C1'" . C   A 1 27  ? 152.238 152.980 177.838 1.00 121.72 ? 27  C   A "C1'" 1 
ATOM 355  N N1    . C   A 1 27  ? 152.713 152.984 179.241 1.00 120.24 ? 27  C   A N1    1 
ATOM 356  C C2    . C   A 1 27  ? 153.864 153.700 179.583 1.00 121.43 ? 27  C   A C2    1 
ATOM 357  O O2    . C   A 1 27  ? 154.485 154.318 178.708 1.00 124.73 ? 27  C   A O2    1 
ATOM 358  N N3    . C   A 1 27  ? 154.286 153.702 180.867 1.00 119.91 ? 27  C   A N3    1 
ATOM 359  C C4    . C   A 1 27  ? 153.601 153.028 181.790 1.00 120.41 ? 27  C   A C4    1 
ATOM 360  N N4    . C   A 1 27  ? 154.048 153.054 183.045 1.00 121.70 ? 27  C   A N4    1 
ATOM 361  C C5    . C   A 1 27  ? 152.426 152.294 181.473 1.00 120.34 ? 27  C   A C5    1 
ATOM 362  C C6    . C   A 1 27  ? 152.022 152.302 180.200 1.00 120.12 ? 27  C   A C6    1 
ATOM 363  P P     . A   A 1 28  ? 153.080 148.534 176.034 1.00 125.43 ? 28  A   A P     1 
ATOM 364  O OP1   . A   A 1 28  ? 152.654 147.620 174.946 1.00 123.91 ? 28  A   A OP1   1 
ATOM 365  O OP2   . A   A 1 28  ? 152.908 148.123 177.448 1.00 122.57 ? 28  A   A OP2   1 
ATOM 366  O "O5'" . A   A 1 28  ? 154.607 148.904 175.796 1.00 116.29 ? 28  A   A "O5'" 1 
ATOM 367  C "C5'" . A   A 1 28  ? 154.983 149.739 174.713 1.00 118.39 ? 28  A   A "C5'" 1 
ATOM 368  C "C4'" . A   A 1 28  ? 156.354 150.322 174.923 1.00 121.86 ? 28  A   A "C4'" 1 
ATOM 369  O "O4'" . A   A 1 28  ? 156.289 151.409 175.880 1.00 120.02 ? 28  A   A "O4'" 1 
ATOM 370  C "C3'" . A   A 1 28  ? 157.384 149.375 175.512 1.00 122.63 ? 28  A   A "C3'" 1 
ATOM 371  O "O3'" . A   A 1 28  ? 157.951 148.513 174.544 1.00 122.46 ? 28  A   A "O3'" 1 
ATOM 372  C "C2'" . A   A 1 28  ? 158.385 150.326 176.149 1.00 119.20 ? 28  A   A "C2'" 1 
ATOM 373  O "O2'" . A   A 1 28  ? 159.251 150.873 175.168 1.00 117.78 ? 28  A   A "O2'" 1 
ATOM 374  C "C1'" . A   A 1 28  ? 157.465 151.435 176.659 1.00 119.07 ? 28  A   A "C1'" 1 
ATOM 375  N N9    . A   A 1 28  ? 157.094 151.240 178.072 1.00 118.37 ? 28  A   A N9    1 
ATOM 376  C C8    . A   A 1 28  ? 155.895 150.809 178.582 1.00 119.29 ? 28  A   A C8    1 
ATOM 377  N N7    . A   A 1 28  ? 155.871 150.739 179.889 1.00 116.50 ? 28  A   A N7    1 
ATOM 378  C C5    . A   A 1 28  ? 157.140 151.154 180.262 1.00 115.40 ? 28  A   A C5    1 
ATOM 379  C C6    . A   A 1 28  ? 157.754 151.303 181.511 1.00 118.00 ? 28  A   A C6    1 
ATOM 380  N N6    . A   A 1 28  ? 157.141 151.042 182.663 1.00 120.77 ? 28  A   A N6    1 
ATOM 381  N N1    . A   A 1 28  ? 159.030 151.739 181.541 1.00 119.40 ? 28  A   A N1    1 
ATOM 382  C C2    . A   A 1 28  ? 159.641 152.002 180.383 1.00 118.14 ? 28  A   A C2    1 
ATOM 383  N N3    . A   A 1 28  ? 159.171 151.899 179.144 1.00 117.63 ? 28  A   A N3    1 
ATOM 384  C C4    . A   A 1 28  ? 157.902 151.465 179.155 1.00 116.14 ? 28  A   A C4    1 
ATOM 385  P P     . C   A 1 29  ? 158.296 146.996 174.930 1.00 120.20 ? 29  C   A P     1 
ATOM 386  O OP1   . C   A 1 29  ? 158.549 146.245 173.677 1.00 116.25 ? 29  C   A OP1   1 
ATOM 387  O OP2   . C   A 1 29  ? 157.264 146.518 175.880 1.00 116.80 ? 29  C   A OP2   1 
ATOM 388  O "O5'" . C   A 1 29  ? 159.676 147.115 175.710 1.00 113.81 ? 29  C   A "O5'" 1 
ATOM 389  C "C5'" . C   A 1 29  ? 160.798 147.719 175.090 1.00 111.49 ? 29  C   A "C5'" 1 
ATOM 390  C "C4'" . C   A 1 29  ? 161.857 148.085 176.096 1.00 112.85 ? 29  C   A "C4'" 1 
ATOM 391  O "O4'" . C   A 1 29  ? 161.365 149.127 176.978 1.00 113.41 ? 29  C   A "O4'" 1 
ATOM 392  C "C3'" . C   A 1 29  ? 162.287 146.980 177.044 1.00 111.76 ? 29  C   A "C3'" 1 
ATOM 393  O "O3'" . C   A 1 29  ? 163.198 146.066 176.462 1.00 113.63 ? 29  C   A "O3'" 1 
ATOM 394  C "C2'" . C   A 1 29  ? 162.869 147.763 178.209 1.00 109.80 ? 29  C   A "C2'" 1 
ATOM 395  O "O2'" . C   A 1 29  ? 164.171 148.232 177.895 1.00 114.45 ? 29  C   A "O2'" 1 
ATOM 396  C "C1'" . C   A 1 29  ? 161.920 148.963 178.266 1.00 112.09 ? 29  C   A "C1'" 1 
ATOM 397  N N1    . C   A 1 29  ? 160.827 148.729 179.233 1.00 107.49 ? 29  C   A N1    1 
ATOM 398  C C2    . C   A 1 29  ? 161.136 148.835 180.585 1.00 113.22 ? 29  C   A C2    1 
ATOM 399  O O2    . C   A 1 29  ? 162.294 149.134 180.907 1.00 116.39 ? 29  C   A O2    1 
ATOM 400  N N3    . C   A 1 29  ? 160.175 148.610 181.502 1.00 114.11 ? 29  C   A N3    1 
ATOM 401  C C4    . C   A 1 29  ? 158.946 148.288 181.106 1.00 112.38 ? 29  C   A C4    1 
ATOM 402  N N4    . C   A 1 29  ? 158.026 148.077 182.047 1.00 115.10 ? 29  C   A N4    1 
ATOM 403  C C5    . C   A 1 29  ? 158.602 148.169 179.731 1.00 109.80 ? 29  C   A C5    1 
ATOM 404  C C6    . C   A 1 29  ? 159.567 148.393 178.835 1.00 108.16 ? 29  C   A C6    1 
ATOM 405  P P     . G   A 1 30  ? 163.198 144.530 176.933 1.00 116.69 ? 30  G   A P     1 
ATOM 406  O OP1   . G   A 1 30  ? 164.110 143.766 176.049 1.00 116.79 ? 30  G   A OP1   1 
ATOM 407  O OP2   . G   A 1 30  ? 161.787 144.100 177.078 1.00 115.22 ? 30  G   A OP2   1 
ATOM 408  O "O5'" . G   A 1 30  ? 163.851 144.573 178.383 1.00 108.07 ? 30  G   A "O5'" 1 
ATOM 409  C "C5'" . G   A 1 30  ? 165.209 144.945 178.552 1.00 113.17 ? 30  G   A "C5'" 1 
ATOM 410  C "C4'" . G   A 1 30  ? 165.547 145.191 180.001 1.00 113.96 ? 30  G   A "C4'" 1 
ATOM 411  O "O4'" . G   A 1 30  ? 164.716 146.252 180.536 1.00 114.30 ? 30  G   A "O4'" 1 
ATOM 412  C "C3'" . G   A 1 30  ? 165.311 144.032 180.953 1.00 111.91 ? 30  G   A "C3'" 1 
ATOM 413  O "O3'" . G   A 1 30  ? 166.340 143.062 180.908 1.00 113.28 ? 30  G   A "O3'" 1 
ATOM 414  C "C2'" . G   A 1 30  ? 165.199 144.736 182.297 1.00 109.99 ? 30  G   A "C2'" 1 
ATOM 415  O "O2'" . G   A 1 30  ? 166.484 145.083 182.786 1.00 108.87 ? 30  G   A "O2'" 1 
ATOM 416  C "C1'" . G   A 1 30  ? 164.470 146.021 181.906 1.00 109.93 ? 30  G   A "C1'" 1 
ATOM 417  N N9    . G   A 1 30  ? 163.016 145.917 182.122 1.00 109.94 ? 30  G   A N9    1 
ATOM 418  C C8    . G   A 1 30  ? 162.027 145.833 181.177 1.00 112.66 ? 30  G   A C8    1 
ATOM 419  N N7    . G   A 1 30  ? 160.832 145.750 181.697 1.00 112.09 ? 30  G   A N7    1 
ATOM 420  C C5    . G   A 1 30  ? 161.048 145.782 183.066 1.00 107.62 ? 30  G   A C5    1 
ATOM 421  C C6    . G   A 1 30  ? 160.136 145.724 184.148 1.00 110.49 ? 30  G   A C6    1 
ATOM 422  O O6    . G   A 1 30  ? 158.905 145.631 184.114 1.00 116.01 ? 30  G   A O6    1 
ATOM 423  N N1    . G   A 1 30  ? 160.788 145.782 185.374 1.00 107.65 ? 30  G   A N1    1 
ATOM 424  C C2    . G   A 1 30  ? 162.144 145.887 185.537 1.00 106.97 ? 30  G   A C2    1 
ATOM 425  N N2    . G   A 1 30  ? 162.613 145.932 186.788 1.00 105.67 ? 30  G   A N2    1 
ATOM 426  N N3    . G   A 1 30  ? 163.002 145.939 184.537 1.00 109.75 ? 30  G   A N3    1 
ATOM 427  C C4    . G   A 1 30  ? 162.390 145.884 183.341 1.00 107.86 ? 30  G   A C4    1 
ATOM 428  P P     . U   A 1 31  ? 165.994 141.510 181.135 1.00 127.70 ? 31  U   A P     1 
ATOM 429  O OP1   . U   A 1 31  ? 167.207 140.710 180.838 1.00 124.11 ? 31  U   A OP1   1 
ATOM 430  O OP2   . U   A 1 31  ? 164.730 141.218 180.418 1.00 123.07 ? 31  U   A OP2   1 
ATOM 431  O "O5'" . U   A 1 31  ? 165.713 141.403 182.697 1.00 124.34 ? 31  U   A "O5'" 1 
ATOM 432  C "C5'" . U   A 1 31  ? 166.736 141.688 183.639 1.00 122.57 ? 31  U   A "C5'" 1 
ATOM 433  C "C4'" . U   A 1 31  ? 166.177 141.873 185.027 1.00 120.81 ? 31  U   A "C4'" 1 
ATOM 434  O "O4'" . U   A 1 31  ? 165.241 142.981 185.039 1.00 121.72 ? 31  U   A "O4'" 1 
ATOM 435  C "C3'" . U   A 1 31  ? 165.376 140.708 185.584 1.00 120.87 ? 31  U   A "C3'" 1 
ATOM 436  O "O3'" . U   A 1 31  ? 166.193 139.677 186.108 1.00 121.47 ? 31  U   A "O3'" 1 
ATOM 437  C "C2'" . U   A 1 31  ? 164.503 141.382 186.630 1.00 122.17 ? 31  U   A "C2'" 1 
ATOM 438  O "O2'" . U   A 1 31  ? 165.245 141.634 187.812 1.00 120.36 ? 31  U   A "O2'" 1 
ATOM 439  C "C1'" . U   A 1 31  ? 164.200 142.721 185.954 1.00 121.41 ? 31  U   A "C1'" 1 
ATOM 440  N N1    . U   A 1 31  ? 162.918 142.687 185.217 1.00 115.53 ? 31  U   A N1    1 
ATOM 441  C C2    . U   A 1 31  ? 161.758 142.705 185.960 1.00 120.38 ? 31  U   A C2    1 
ATOM 442  O O2    . U   A 1 31  ? 161.753 142.754 187.176 1.00 126.53 ? 31  U   A O2    1 
ATOM 443  N N3    . U   A 1 31  ? 160.600 142.666 185.232 1.00 121.27 ? 31  U   A N3    1 
ATOM 444  C C4    . U   A 1 31  ? 160.485 142.607 183.863 1.00 119.53 ? 31  U   A C4    1 
ATOM 445  O O4    . U   A 1 31  ? 159.364 142.578 183.356 1.00 121.25 ? 31  U   A O4    1 
ATOM 446  C C5    . U   A 1 31  ? 161.731 142.592 183.164 1.00 117.12 ? 31  U   A C5    1 
ATOM 447  C C6    . U   A 1 31  ? 162.876 142.630 183.848 1.00 114.50 ? 31  U   A C6    1 
ATOM 448  P P     . A   A 1 32  ? 165.858 138.140 185.784 1.00 124.30 ? 32  A   A P     1 
ATOM 449  O OP1   . A   A 1 32  ? 167.120 137.367 185.863 1.00 123.29 ? 32  A   A OP1   1 
ATOM 450  O OP2   . A   A 1 32  ? 165.058 138.102 184.536 1.00 122.29 ? 32  A   A OP2   1 
ATOM 451  O "O5'" . A   A 1 32  ? 164.923 137.684 186.990 1.00 119.51 ? 32  A   A "O5'" 1 
ATOM 452  C "C5'" . A   A 1 32  ? 165.459 137.486 188.290 1.00 120.85 ? 32  A   A "C5'" 1 
ATOM 453  C "C4'" . A   A 1 32  ? 164.383 137.506 189.348 1.00 118.89 ? 32  A   A "C4'" 1 
ATOM 454  O "O4'" . A   A 1 32  ? 163.631 138.746 189.256 1.00 118.87 ? 32  A   A "O4'" 1 
ATOM 455  C "C3'" . A   A 1 32  ? 163.319 136.425 189.246 1.00 120.92 ? 32  A   A "C3'" 1 
ATOM 456  O "O3'" . A   A 1 32  ? 163.730 135.177 189.774 1.00 124.16 ? 32  A   A "O3'" 1 
ATOM 457  C "C2'" . A   A 1 32  ? 162.152 137.051 189.991 1.00 121.01 ? 32  A   A "C2'" 1 
ATOM 458  O "O2'" . A   A 1 32  ? 162.370 137.002 191.393 1.00 120.71 ? 32  A   A "O2'" 1 
ATOM 459  C "C1'" . A   A 1 32  ? 162.269 138.503 189.539 1.00 116.64 ? 32  A   A "C1'" 1 
ATOM 460  N N9    . A   A 1 32  ? 161.501 138.727 188.305 1.00 115.28 ? 32  A   A N9    1 
ATOM 461  C C8    . A   A 1 32  ? 161.985 138.819 187.026 1.00 115.80 ? 32  A   A C8    1 
ATOM 462  N N7    . A   A 1 32  ? 161.054 139.005 186.126 1.00 116.31 ? 32  A   A N7    1 
ATOM 463  C C5    . A   A 1 32  ? 159.884 139.028 186.869 1.00 117.54 ? 32  A   A C5    1 
ATOM 464  C C6    . A   A 1 32  ? 158.544 139.191 186.501 1.00 119.88 ? 32  A   A C6    1 
ATOM 465  N N6    . A   A 1 32  ? 158.150 139.371 185.243 1.00 123.82 ? 32  A   A N6    1 
ATOM 466  N N1    . A   A 1 32  ? 157.616 139.165 187.477 1.00 114.99 ? 32  A   A N1    1 
ATOM 467  C C2    . A   A 1 32  ? 158.017 138.986 188.739 1.00 114.83 ? 32  A   A C2    1 
ATOM 468  N N3    . A   A 1 32  ? 159.248 138.823 189.211 1.00 115.77 ? 32  A   A N3    1 
ATOM 469  C C4    . A   A 1 32  ? 160.142 138.854 188.211 1.00 115.71 ? 32  A   A C4    1 
ATOM 470  P P     . G   A 1 33  ? 163.430 133.826 188.956 1.00 145.81 ? 33  G   A P     1 
ATOM 471  O OP1   . G   A 1 33  ? 164.322 132.761 189.479 1.00 138.68 ? 33  G   A OP1   1 
ATOM 472  O OP2   . G   A 1 33  ? 163.462 134.164 187.511 1.00 131.81 ? 33  G   A OP2   1 
ATOM 473  O "O5'" . G   A 1 33  ? 161.929 133.456 189.345 1.00 138.84 ? 33  G   A "O5'" 1 
ATOM 474  C "C5'" . G   A 1 33  ? 161.634 132.781 190.560 1.00 135.48 ? 33  G   A "C5'" 1 
ATOM 475  C "C4'" . G   A 1 33  ? 160.162 132.842 190.889 1.00 134.51 ? 33  G   A "C4'" 1 
ATOM 476  O "O4'" . G   A 1 33  ? 159.703 134.216 190.784 1.00 135.32 ? 33  G   A "O4'" 1 
ATOM 477  C "C3'" . G   A 1 33  ? 159.231 132.068 189.964 1.00 135.14 ? 33  G   A "C3'" 1 
ATOM 478  O "O3'" . G   A 1 33  ? 159.146 130.690 190.279 1.00 136.06 ? 33  G   A "O3'" 1 
ATOM 479  C "C2'" . G   A 1 33  ? 157.913 132.807 190.130 1.00 137.52 ? 33  G   A "C2'" 1 
ATOM 480  O "O2'" . G   A 1 33  ? 157.281 132.438 191.347 1.00 135.01 ? 33  G   A "O2'" 1 
ATOM 481  C "C1'" . G   A 1 33  ? 158.396 134.249 190.254 1.00 135.93 ? 33  G   A "C1'" 1 
ATOM 482  N N9    . G   A 1 33  ? 158.455 134.907 188.939 1.00 134.58 ? 33  G   A N9    1 
ATOM 483  C C8    . G   A 1 33  ? 159.581 135.275 188.246 1.00 131.88 ? 33  G   A C8    1 
ATOM 484  N N7    . G   A 1 33  ? 159.313 135.832 187.098 1.00 131.49 ? 33  G   A N7    1 
ATOM 485  C C5    . G   A 1 33  ? 157.928 135.823 187.033 1.00 132.74 ? 33  G   A C5    1 
ATOM 486  C C6    . G   A 1 33  ? 157.056 136.292 186.025 1.00 132.97 ? 33  G   A C6    1 
ATOM 487  O O6    . G   A 1 33  ? 157.338 136.826 184.949 1.00 134.41 ? 33  G   A O6    1 
ATOM 488  N N1    . G   A 1 33  ? 155.726 136.080 186.361 1.00 133.63 ? 33  G   A N1    1 
ATOM 489  C C2    . G   A 1 33  ? 155.282 135.503 187.522 1.00 134.52 ? 33  G   A C2    1 
ATOM 490  N N2    . G   A 1 33  ? 153.953 135.392 187.658 1.00 132.28 ? 33  G   A N2    1 
ATOM 491  N N3    . G   A 1 33  ? 156.083 135.060 188.472 1.00 137.50 ? 33  G   A N3    1 
ATOM 492  C C4    . G   A 1 33  ? 157.382 135.254 188.160 1.00 135.66 ? 33  G   A C4    1 
ATOM 493  P P     . G   A 1 34  ? 158.867 129.616 189.117 1.00 151.39 ? 34  G   A P     1 
ATOM 494  O OP1   . G   A 1 34  ? 159.099 128.259 189.672 1.00 149.36 ? 34  G   A OP1   1 
ATOM 495  O OP2   . G   A 1 34  ? 159.615 130.060 187.916 1.00 146.22 ? 34  G   A OP2   1 
ATOM 496  O "O5'" . G   A 1 34  ? 157.311 129.762 188.806 1.00 151.40 ? 34  G   A "O5'" 1 
ATOM 497  C "C5'" . G   A 1 34  ? 156.332 129.252 189.700 1.00 148.58 ? 34  G   A "C5'" 1 
ATOM 498  C "C4'" . G   A 1 34  ? 154.931 129.478 189.185 1.00 150.13 ? 34  G   A "C4'" 1 
ATOM 499  O "O4'" . G   A 1 34  ? 154.751 130.882 188.860 1.00 148.99 ? 34  G   A "O4'" 1 
ATOM 500  C "C3'" . G   A 1 34  ? 154.561 128.749 187.900 1.00 153.08 ? 34  G   A "C3'" 1 
ATOM 501  O "O3'" . G   A 1 34  ? 154.174 127.403 188.120 1.00 154.99 ? 34  G   A "O3'" 1 
ATOM 502  C "C2'" . G   A 1 34  ? 153.443 129.615 187.336 1.00 151.14 ? 34  G   A "C2'" 1 
ATOM 503  O "O2'" . G   A 1 34  ? 152.220 129.356 188.010 1.00 147.99 ? 34  G   A "O2'" 1 
ATOM 504  C "C1'" . G   A 1 34  ? 153.920 131.014 187.726 1.00 148.12 ? 34  G   A "C1'" 1 
ATOM 505  N N9    . G   A 1 34  ? 154.704 131.646 186.648 1.00 146.88 ? 34  G   A N9    1 
ATOM 506  C C8    . G   A 1 34  ? 156.050 131.916 186.660 1.00 147.20 ? 34  G   A C8    1 
ATOM 507  N N7    . G   A 1 34  ? 156.471 132.480 185.562 1.00 146.03 ? 34  G   A N7    1 
ATOM 508  C C5    . G   A 1 34  ? 155.333 132.590 184.778 1.00 148.78 ? 34  G   A C5    1 
ATOM 509  C C6    . G   A 1 34  ? 155.168 133.122 183.475 1.00 149.80 ? 34  G   A C6    1 
ATOM 510  O O6    . G   A 1 34  ? 156.021 133.621 182.732 1.00 149.09 ? 34  G   A O6    1 
ATOM 511  N N1    . G   A 1 34  ? 153.847 133.038 183.052 1.00 148.54 ? 34  G   A N1    1 
ATOM 512  C C2    . G   A 1 34  ? 152.815 132.508 183.784 1.00 147.24 ? 34  G   A C2    1 
ATOM 513  N N2    . G   A 1 34  ? 151.609 132.516 183.201 1.00 145.05 ? 34  G   A N2    1 
ATOM 514  N N3    . G   A 1 34  ? 152.956 132.007 185.000 1.00 147.17 ? 34  G   A N3    1 
ATOM 515  C C4    . G   A 1 34  ? 154.232 132.080 185.432 1.00 148.22 ? 34  G   A C4    1 
ATOM 516  P P     . G   A 1 35  ? 154.664 126.241 187.122 1.00 169.35 ? 35  G   A P     1 
ATOM 517  O OP1   . G   A 1 35  ? 154.508 124.942 187.822 1.00 163.08 ? 35  G   A OP1   1 
ATOM 518  O OP2   . G   A 1 35  ? 155.991 126.629 186.580 1.00 162.82 ? 35  G   A OP2   1 
ATOM 519  O "O5'" . G   A 1 35  ? 153.609 126.278 185.928 1.00 161.54 ? 35  G   A "O5'" 1 
ATOM 520  C "C5'" . G   A 1 35  ? 152.280 125.810 186.109 1.00 159.50 ? 35  G   A "C5'" 1 
ATOM 521  C "C4'" . G   A 1 35  ? 151.378 126.271 184.993 1.00 160.49 ? 35  G   A "C4'" 1 
ATOM 522  O "O4'" . G   A 1 35  ? 151.536 127.703 184.810 1.00 158.38 ? 35  G   A "O4'" 1 
ATOM 523  C "C3'" . G   A 1 35  ? 151.668 125.688 183.616 1.00 164.36 ? 35  G   A "C3'" 1 
ATOM 524  O "O3'" . G   A 1 35  ? 151.097 124.407 183.415 1.00 166.64 ? 35  G   A "O3'" 1 
ATOM 525  C "C2'" . G   A 1 35  ? 151.113 126.751 182.682 1.00 163.55 ? 35  G   A "C2'" 1 
ATOM 526  O "O2'" . G   A 1 35  ? 149.698 126.668 182.613 1.00 162.78 ? 35  G   A "O2'" 1 
ATOM 527  C "C1'" . G   A 1 35  ? 151.483 128.024 183.437 1.00 161.58 ? 35  G   A "C1'" 1 
ATOM 528  N N9    . G   A 1 35  ? 152.809 128.522 183.032 1.00 162.11 ? 35  G   A N9    1 
ATOM 529  C C8    . G   A 1 35  ? 153.960 128.504 183.780 1.00 160.96 ? 35  G   A C8    1 
ATOM 530  N N7    . G   A 1 35  ? 154.983 129.012 183.152 1.00 159.72 ? 35  G   A N7    1 
ATOM 531  C C5    . G   A 1 35  ? 154.474 129.382 181.917 1.00 160.99 ? 35  G   A C5    1 
ATOM 532  C C6    . G   A 1 35  ? 155.111 129.989 180.810 1.00 161.97 ? 35  G   A C6    1 
ATOM 533  O O6    . G   A 1 35  ? 156.291 130.329 180.682 1.00 161.60 ? 35  G   A O6    1 
ATOM 534  N N1    . G   A 1 35  ? 154.225 130.186 179.757 1.00 163.48 ? 35  G   A N1    1 
ATOM 535  C C2    . G   A 1 35  ? 152.894 129.852 179.765 1.00 160.35 ? 35  G   A C2    1 
ATOM 536  N N2    . G   A 1 35  ? 152.205 130.131 178.651 1.00 159.83 ? 35  G   A N2    1 
ATOM 537  N N3    . G   A 1 35  ? 152.286 129.289 180.793 1.00 159.76 ? 35  G   A N3    1 
ATOM 538  C C4    . G   A 1 35  ? 153.133 129.086 181.824 1.00 161.26 ? 35  G   A C4    1 
ATOM 539  P P     . C   A 1 36  ? 151.827 123.343 182.457 1.00 176.96 ? 36  C   A P     1 
ATOM 540  O OP1   . C   A 1 36  ? 151.070 122.069 182.525 1.00 169.37 ? 36  C   A OP1   1 
ATOM 541  O OP2   . C   A 1 36  ? 153.274 123.359 182.788 1.00 170.20 ? 36  C   A OP2   1 
ATOM 542  O "O5'" . C   A 1 36  ? 151.655 123.943 180.989 1.00 168.72 ? 36  C   A "O5'" 1 
ATOM 543  C "C5'" . C   A 1 36  ? 150.439 123.785 180.271 1.00 166.49 ? 36  C   A "C5'" 1 
ATOM 544  C "C4'" . C   A 1 36  ? 150.487 124.481 178.933 1.00 168.39 ? 36  C   A "C4'" 1 
ATOM 545  O "O4'" . C   A 1 36  ? 150.951 125.846 179.111 1.00 169.49 ? 36  C   A "O4'" 1 
ATOM 546  C "C3'" . C   A 1 36  ? 151.444 123.899 177.902 1.00 170.65 ? 36  C   A "C3'" 1 
ATOM 547  O "O3'" . C   A 1 36  ? 150.920 122.771 177.220 1.00 171.73 ? 36  C   A "O3'" 1 
ATOM 548  C "C2'" . C   A 1 36  ? 151.710 125.090 176.992 1.00 168.75 ? 36  C   A "C2'" 1 
ATOM 549  O "O2'" . C   A 1 36  ? 150.624 125.297 176.102 1.00 168.56 ? 36  C   A "O2'" 1 
ATOM 550  C "C1'" . C   A 1 36  ? 151.735 126.238 178.002 1.00 167.54 ? 36  C   A "C1'" 1 
ATOM 551  N N1    . C   A 1 36  ? 153.109 126.505 178.472 1.00 161.85 ? 36  C   A N1    1 
ATOM 552  C C2    . C   A 1 36  ? 153.983 127.184 177.624 1.00 162.39 ? 36  C   A C2    1 
ATOM 553  O O2    . C   A 1 36  ? 153.587 127.559 176.512 1.00 158.54 ? 36  C   A O2    1 
ATOM 554  N N3    . C   A 1 36  ? 155.244 127.419 178.037 1.00 167.49 ? 36  C   A N3    1 
ATOM 555  C C4    . C   A 1 36  ? 155.638 127.003 179.242 1.00 169.09 ? 36  C   A C4    1 
ATOM 556  N N4    . C   A 1 36  ? 156.896 127.258 179.601 1.00 169.33 ? 36  C   A N4    1 
ATOM 557  C C5    . C   A 1 36  ? 154.770 126.303 180.126 1.00 166.26 ? 36  C   A C5    1 
ATOM 558  C C6    . C   A 1 36  ? 153.524 126.079 179.701 1.00 163.06 ? 36  C   A C6    1 
ATOM 559  P P     . A   A 1 37  ? 151.892 121.570 176.770 1.00 173.22 ? 37  A   A P     1 
ATOM 560  O OP1   . A   A 1 37  ? 151.054 120.393 176.433 1.00 166.31 ? 37  A   A OP1   1 
ATOM 561  O OP2   . A   A 1 37  ? 152.960 121.445 177.791 1.00 169.10 ? 37  A   A OP2   1 
ATOM 562  O "O5'" . A   A 1 37  ? 152.561 122.086 175.419 1.00 170.11 ? 37  A   A "O5'" 1 
ATOM 563  C "C5'" . A   A 1 37  ? 151.811 122.169 174.216 1.00 167.15 ? 37  A   A "C5'" 1 
ATOM 564  C "C4'" . A   A 1 37  ? 152.562 122.927 173.150 1.00 170.19 ? 37  A   A "C4'" 1 
ATOM 565  O "O4'" . A   A 1 37  ? 153.156 124.115 173.734 1.00 170.97 ? 37  A   A "O4'" 1 
ATOM 566  C "C3'" . A   A 1 37  ? 153.737 122.197 172.513 1.00 172.18 ? 37  A   A "C3'" 1 
ATOM 567  O "O3'" . A   A 1 37  ? 153.341 121.324 171.468 1.00 172.45 ? 37  A   A "O3'" 1 
ATOM 568  C "C2'" . A   A 1 37  ? 154.625 123.338 172.044 1.00 169.50 ? 37  A   A "C2'" 1 
ATOM 569  O "O2'" . A   A 1 37  ? 154.127 123.896 170.837 1.00 165.74 ? 37  A   A "O2'" 1 
ATOM 570  C "C1'" . A   A 1 37  ? 154.424 124.354 173.165 1.00 168.57 ? 37  A   A "C1'" 1 
ATOM 571  N N9    . A   A 1 37  ? 155.432 124.200 174.226 1.00 164.30 ? 37  A   A N9    1 
ATOM 572  C C8    . A   A 1 37  ? 155.281 123.545 175.420 1.00 164.46 ? 37  A   A C8    1 
ATOM 573  N N7    . A   A 1 37  ? 156.353 123.566 176.170 1.00 166.02 ? 37  A   A N7    1 
ATOM 574  C C5    . A   A 1 37  ? 157.267 124.284 175.415 1.00 167.52 ? 37  A   A C5    1 
ATOM 575  C C6    . A   A 1 37  ? 158.598 124.656 175.657 1.00 169.46 ? 37  A   A C6    1 
ATOM 576  N N6    . A   A 1 37  ? 159.252 124.342 176.774 1.00 168.24 ? 37  A   A N6    1 
ATOM 577  N N1    . A   A 1 37  ? 159.235 125.368 174.703 1.00 170.55 ? 37  A   A N1    1 
ATOM 578  C C2    . A   A 1 37  ? 158.565 125.679 173.585 1.00 167.45 ? 37  A   A C2    1 
ATOM 579  N N3    . A   A 1 37  ? 157.313 125.389 173.242 1.00 163.40 ? 37  A   A N3    1 
ATOM 580  C C4    . A   A 1 37  ? 156.715 124.681 174.213 1.00 164.52 ? 37  A   A C4    1 
ATOM 581  P P     . A   A 1 38  ? 154.200 120.006 171.138 1.00 181.21 ? 38  A   A P     1 
ATOM 582  O OP1   . A   A 1 38  ? 153.434 119.184 170.168 1.00 172.47 ? 38  A   A OP1   1 
ATOM 583  O OP2   . A   A 1 38  ? 154.636 119.412 172.427 1.00 176.62 ? 38  A   A OP2   1 
ATOM 584  O "O5'" . A   A 1 38  ? 155.489 120.560 170.386 1.00 172.31 ? 38  A   A "O5'" 1 
ATOM 585  C "C5'" . A   A 1 38  ? 155.370 121.255 169.155 1.00 168.37 ? 38  A   A "C5'" 1 
ATOM 586  C "C4'" . A   A 1 38  ? 156.642 121.987 168.814 1.00 172.27 ? 38  A   A "C4'" 1 
ATOM 587  O "O4'" . A   A 1 38  ? 156.993 122.887 169.898 1.00 173.18 ? 38  A   A "O4'" 1 
ATOM 588  C "C3'" . A   A 1 38  ? 157.881 121.123 168.637 1.00 173.46 ? 38  A   A "C3'" 1 
ATOM 589  O "O3'" . A   A 1 38  ? 157.960 120.521 167.356 1.00 171.18 ? 38  A   A "O3'" 1 
ATOM 590  C "C2'" . A   A 1 38  ? 159.010 122.103 168.923 1.00 171.92 ? 38  A   A "C2'" 1 
ATOM 591  O "O2'" . A   A 1 38  ? 159.245 122.942 167.801 1.00 169.89 ? 38  A   A "O2'" 1 
ATOM 592  C "C1'" . A   A 1 38  ? 158.396 122.947 170.039 1.00 171.17 ? 38  A   A "C1'" 1 
ATOM 593  N N9    . A   A 1 38  ? 158.754 122.422 171.368 1.00 169.65 ? 38  A   A N9    1 
ATOM 594  C C8    . A   A 1 38  ? 157.989 121.664 172.216 1.00 168.84 ? 38  A   A C8    1 
ATOM 595  N N7    . A   A 1 38  ? 158.604 121.344 173.329 1.00 169.51 ? 38  A   A N7    1 
ATOM 596  C C5    . A   A 1 38  ? 159.857 121.927 173.199 1.00 172.88 ? 38  A   A C5    1 
ATOM 597  C C6    . A   A 1 38  ? 160.984 121.959 174.038 1.00 173.02 ? 38  A   A C6    1 
ATOM 598  N N6    . A   A 1 38  ? 161.032 121.364 175.231 1.00 170.58 ? 38  A   A N6    1 
ATOM 599  N N1    . A   A 1 38  ? 162.076 122.630 173.605 1.00 172.13 ? 38  A   A N1    1 
ATOM 600  C C2    . A   A 1 38  ? 162.021 123.224 172.407 1.00 171.33 ? 38  A   A C2    1 
ATOM 601  N N3    . A   A 1 38  ? 161.024 123.268 171.530 1.00 170.90 ? 38  A   A N3    1 
ATOM 602  C C4    . A   A 1 38  ? 159.961 122.592 171.993 1.00 171.75 ? 38  A   A C4    1 
ATOM 603  P P     . U   A 1 44  ? 170.217 123.062 178.859 1.00 193.28 ? 44  U   A P     1 
ATOM 604  O OP1   . U   A 1 44  ? 170.145 121.580 178.812 1.00 190.06 ? 44  U   A OP1   1 
ATOM 605  O OP2   . U   A 1 44  ? 171.525 123.732 179.069 1.00 188.47 ? 44  U   A OP2   1 
ATOM 606  O "O5'" . U   A 1 44  ? 169.612 123.623 177.498 1.00 191.46 ? 44  U   A "O5'" 1 
ATOM 607  C "C5'" . U   A 1 44  ? 170.462 124.167 176.501 1.00 189.94 ? 44  U   A "C5'" 1 
ATOM 608  C "C4'" . U   A 1 44  ? 169.696 124.528 175.254 1.00 192.45 ? 44  U   A "C4'" 1 
ATOM 609  O "O4'" . U   A 1 44  ? 169.137 123.333 174.648 1.00 192.57 ? 44  U   A "O4'" 1 
ATOM 610  C "C3'" . U   A 1 44  ? 168.493 125.437 175.442 1.00 191.55 ? 44  U   A "C3'" 1 
ATOM 611  O "O3'" . U   A 1 44  ? 168.847 126.802 175.582 1.00 193.24 ? 44  U   A "O3'" 1 
ATOM 612  C "C2'" . U   A 1 44  ? 167.664 125.145 174.199 1.00 189.25 ? 44  U   A "C2'" 1 
ATOM 613  O "O2'" . U   A 1 44  ? 168.187 125.833 173.073 1.00 189.90 ? 44  U   A "O2'" 1 
ATOM 614  C "C1'" . U   A 1 44  ? 167.917 123.647 174.009 1.00 189.18 ? 44  U   A "C1'" 1 
ATOM 615  N N1    . U   A 1 44  ? 166.838 122.822 174.596 1.00 187.02 ? 44  U   A N1    1 
ATOM 616  C C2    . U   A 1 44  ? 165.673 122.708 173.866 1.00 188.15 ? 44  U   A C2    1 
ATOM 617  O O2    . U   A 1 44  ? 165.512 123.253 172.788 1.00 188.51 ? 44  U   A O2    1 
ATOM 618  N N3    . U   A 1 44  ? 164.691 121.942 174.439 1.00 188.23 ? 44  U   A N3    1 
ATOM 619  C C4    . U   A 1 44  ? 164.768 121.282 175.648 1.00 188.29 ? 44  U   A C4    1 
ATOM 620  O O4    . U   A 1 44  ? 163.804 120.622 176.037 1.00 187.40 ? 44  U   A O4    1 
ATOM 621  C C5    . U   A 1 44  ? 166.008 121.446 176.345 1.00 186.96 ? 44  U   A C5    1 
ATOM 622  C C6    . U   A 1 44  ? 166.979 122.192 175.809 1.00 186.03 ? 44  U   A C6    1 
ATOM 623  P P     . U   A 1 45  ? 167.967 127.778 176.506 1.00 180.16 ? 45  U   A P     1 
ATOM 624  O OP1   . U   A 1 45  ? 168.849 128.871 176.988 1.00 177.08 ? 45  U   A OP1   1 
ATOM 625  O OP2   . U   A 1 45  ? 167.225 126.944 177.485 1.00 172.62 ? 45  U   A OP2   1 
ATOM 626  O "O5'" . U   A 1 45  ? 166.906 128.407 175.499 1.00 176.12 ? 45  U   A "O5'" 1 
ATOM 627  C "C5'" . U   A 1 45  ? 167.330 129.058 174.311 1.00 176.26 ? 45  U   A "C5'" 1 
ATOM 628  C "C4'" . U   A 1 45  ? 166.259 129.023 173.252 1.00 177.01 ? 45  U   A "C4'" 1 
ATOM 629  O "O4'" . U   A 1 45  ? 165.866 127.648 173.006 1.00 177.61 ? 45  U   A "O4'" 1 
ATOM 630  C "C3'" . U   A 1 45  ? 164.958 129.728 173.604 1.00 176.47 ? 45  U   A "C3'" 1 
ATOM 631  O "O3'" . U   A 1 45  ? 165.015 131.122 173.362 1.00 176.53 ? 45  U   A "O3'" 1 
ATOM 632  C "C2'" . U   A 1 45  ? 163.935 129.006 172.738 1.00 174.97 ? 45  U   A "C2'" 1 
ATOM 633  O "O2'" . U   A 1 45  ? 163.966 129.499 171.408 1.00 174.99 ? 45  U   A "O2'" 1 
ATOM 634  C "C1'" . U   A 1 45  ? 164.483 127.579 172.738 1.00 175.01 ? 45  U   A "C1'" 1 
ATOM 635  N N1    . U   A 1 45  ? 163.854 126.726 173.769 1.00 173.76 ? 45  U   A N1    1 
ATOM 636  C C2    . U   A 1 45  ? 162.569 126.269 173.555 1.00 173.77 ? 45  U   A C2    1 
ATOM 637  O O2    . U   A 1 45  ? 161.922 126.546 172.560 1.00 172.25 ? 45  U   A O2    1 
ATOM 638  N N3    . U   A 1 45  ? 162.063 125.477 174.556 1.00 174.92 ? 45  U   A N3    1 
ATOM 639  C C4    . U   A 1 45  ? 162.706 125.099 175.718 1.00 174.54 ? 45  U   A C4    1 
ATOM 640  O O4    . U   A 1 45  ? 162.131 124.378 176.531 1.00 172.32 ? 45  U   A O4    1 
ATOM 641  C C5    . U   A 1 45  ? 164.034 125.607 175.861 1.00 174.67 ? 45  U   A C5    1 
ATOM 642  C C6    . U   A 1 45  ? 164.547 126.382 174.904 1.00 174.26 ? 45  U   A C6    1 
ATOM 643  P P     . G   A 1 46  ? 164.086 132.130 174.197 1.00 169.50 ? 46  G   A P     1 
ATOM 644  O OP1   . G   A 1 46  ? 164.580 133.509 173.955 1.00 163.49 ? 46  G   A OP1   1 
ATOM 645  O OP2   . G   A 1 46  ? 164.003 131.618 175.588 1.00 166.12 ? 46  G   A OP2   1 
ATOM 646  O "O5'" . G   A 1 46  ? 162.649 131.989 173.520 1.00 164.01 ? 46  G   A "O5'" 1 
ATOM 647  C "C5'" . G   A 1 46  ? 162.436 132.373 172.168 1.00 162.41 ? 46  G   A "C5'" 1 
ATOM 648  C "C4'" . G   A 1 46  ? 161.122 131.848 171.644 1.00 162.49 ? 46  G   A "C4'" 1 
ATOM 649  O "O4'" . G   A 1 46  ? 161.069 130.411 171.827 1.00 164.12 ? 46  G   A "O4'" 1 
ATOM 650  C "C3'" . G   A 1 46  ? 159.873 132.366 172.344 1.00 165.38 ? 46  G   A "C3'" 1 
ATOM 651  O "O3'" . G   A 1 46  ? 159.444 133.617 171.834 1.00 164.94 ? 46  G   A "O3'" 1 
ATOM 652  C "C2'" . G   A 1 46  ? 158.865 131.247 172.119 1.00 164.22 ? 46  G   A "C2'" 1 
ATOM 653  O "O2'" . G   A 1 46  ? 158.293 131.338 170.824 1.00 162.80 ? 46  G   A "O2'" 1 
ATOM 654  C "C1'" . G   A 1 46  ? 159.760 130.010 172.167 1.00 164.08 ? 46  G   A "C1'" 1 
ATOM 655  N N9    . G   A 1 46  ? 159.803 129.398 173.506 1.00 165.21 ? 46  G   A N9    1 
ATOM 656  C C8    . G   A 1 46  ? 160.922 129.241 174.287 1.00 163.83 ? 46  G   A C8    1 
ATOM 657  N N7    . G   A 1 46  ? 160.679 128.657 175.425 1.00 164.10 ? 46  G   A N7    1 
ATOM 658  C C5    . G   A 1 46  ? 159.313 128.414 175.392 1.00 165.42 ? 46  G   A C5    1 
ATOM 659  C C6    . G   A 1 46  ? 158.477 127.803 176.354 1.00 163.38 ? 46  G   A C6    1 
ATOM 660  O O6    . G   A 1 46  ? 158.782 127.342 177.458 1.00 160.81 ? 46  G   A O6    1 
ATOM 661  N N1    . G   A 1 46  ? 157.157 127.749 175.924 1.00 163.06 ? 46  G   A N1    1 
ATOM 662  C C2    . G   A 1 46  ? 156.693 128.226 174.725 1.00 160.86 ? 46  G   A C2    1 
ATOM 663  N N2    . G   A 1 46  ? 155.381 128.084 174.494 1.00 156.75 ? 46  G   A N2    1 
ATOM 664  N N3    . G   A 1 46  ? 157.464 128.799 173.816 1.00 161.42 ? 46  G   A N3    1 
ATOM 665  C C4    . G   A 1 46  ? 158.754 128.860 174.212 1.00 164.88 ? 46  G   A C4    1 
ATOM 666  P P     . C   A 1 47  ? 158.699 134.671 172.790 1.00 166.70 ? 47  C   A P     1 
ATOM 667  O OP1   . C   A 1 47  ? 158.547 135.943 172.041 1.00 160.77 ? 47  C   A OP1   1 
ATOM 668  O OP2   . C   A 1 47  ? 159.403 134.669 174.096 1.00 163.13 ? 47  C   A OP2   1 
ATOM 669  O "O5'" . C   A 1 47  ? 157.247 134.050 173.006 1.00 162.39 ? 47  C   A "O5'" 1 
ATOM 670  C "C5'" . C   A 1 47  ? 156.248 134.149 172.001 1.00 157.72 ? 47  C   A "C5'" 1 
ATOM 671  C "C4'" . C   A 1 47  ? 154.949 133.529 172.453 1.00 160.77 ? 47  C   A "C4'" 1 
ATOM 672  O "O4'" . C   A 1 47  ? 155.181 132.151 172.838 1.00 162.68 ? 47  C   A "O4'" 1 
ATOM 673  C "C3'" . C   A 1 47  ? 154.299 134.161 173.677 1.00 164.95 ? 47  C   A "C3'" 1 
ATOM 674  O "O3'" . C   A 1 47  ? 153.508 135.290 173.347 1.00 164.71 ? 47  C   A "O3'" 1 
ATOM 675  C "C2'" . C   A 1 47  ? 153.487 133.015 174.267 1.00 162.50 ? 47  C   A "C2'" 1 
ATOM 676  O "O2'" . C   A 1 47  ? 152.246 132.877 173.590 1.00 158.14 ? 47  C   A "O2'" 1 
ATOM 677  C "C1'" . C   A 1 47  ? 154.360 131.805 173.932 1.00 161.32 ? 47  C   A "C1'" 1 
ATOM 678  N N1    . C   A 1 47  ? 155.229 131.395 175.055 1.00 157.28 ? 47  C   A N1    1 
ATOM 679  C C2    . C   A 1 47  ? 154.671 130.777 176.176 1.00 156.20 ? 47  C   A C2    1 
ATOM 680  O O2    . C   A 1 47  ? 153.447 130.592 176.231 1.00 153.19 ? 47  C   A O2    1 
ATOM 681  N N3    . C   A 1 47  ? 155.483 130.401 177.187 1.00 160.02 ? 47  C   A N3    1 
ATOM 682  C C4    . C   A 1 47  ? 156.798 130.611 177.101 1.00 160.71 ? 47  C   A C4    1 
ATOM 683  N N4    . C   A 1 47  ? 157.554 130.223 178.128 1.00 161.76 ? 47  C   A N4    1 
ATOM 684  C C5    . C   A 1 47  ? 157.392 131.234 175.970 1.00 159.02 ? 47  C   A C5    1 
ATOM 685  C C6    . C   A 1 47  ? 156.577 131.601 174.977 1.00 157.76 ? 47  C   A C6    1 
ATOM 686  P P     . U   A 1 48  ? 153.256 136.460 174.420 1.00 167.45 ? 48  U   A P     1 
ATOM 687  O OP1   . U   A 1 48  ? 152.366 137.464 173.786 1.00 158.21 ? 48  U   A OP1   1 
ATOM 688  O OP2   . U   A 1 48  ? 154.574 136.882 174.954 1.00 161.90 ? 48  U   A OP2   1 
ATOM 689  O "O5'" . U   A 1 48  ? 152.441 135.756 175.597 1.00 161.11 ? 48  U   A "O5'" 1 
ATOM 690  C "C5'" . U   A 1 48  ? 151.030 135.605 175.526 1.00 154.34 ? 48  U   A "C5'" 1 
ATOM 691  C "C4'" . U   A 1 48  ? 150.465 135.049 176.811 1.00 155.85 ? 48  U   A "C4'" 1 
ATOM 692  O "O4'" . U   A 1 48  ? 151.177 133.840 177.172 1.00 158.02 ? 48  U   A "O4'" 1 
ATOM 693  C "C3'" . U   A 1 48  ? 150.588 135.936 178.043 1.00 159.74 ? 48  U   A "C3'" 1 
ATOM 694  O "O3'" . U   A 1 48  ? 149.562 136.909 178.122 1.00 159.38 ? 48  U   A "O3'" 1 
ATOM 695  C "C2'" . U   A 1 48  ? 150.551 134.935 179.191 1.00 158.07 ? 48  U   A "C2'" 1 
ATOM 696  O "O2'" . U   A 1 48  ? 149.215 134.567 179.496 1.00 154.69 ? 48  U   A "O2'" 1 
ATOM 697  C "C1'" . U   A 1 48  ? 151.258 133.726 178.577 1.00 159.06 ? 48  U   A "C1'" 1 
ATOM 698  N N1    . U   A 1 48  ? 152.681 133.634 178.969 1.00 159.28 ? 48  U   A N1    1 
ATOM 699  C C2    . U   A 1 48  ? 152.956 133.048 180.186 1.00 157.75 ? 48  U   A C2    1 
ATOM 700  O O2    . U   A 1 48  ? 152.085 132.625 180.926 1.00 153.71 ? 48  U   A O2    1 
ATOM 701  N N3    . U   A 1 48  ? 154.288 132.973 180.505 1.00 158.78 ? 48  U   A N3    1 
ATOM 702  C C4    . U   A 1 48  ? 155.348 133.412 179.741 1.00 158.74 ? 48  U   A C4    1 
ATOM 703  O O4    . U   A 1 48  ? 156.496 133.273 180.167 1.00 156.26 ? 48  U   A O4    1 
ATOM 704  C C5    . U   A 1 48  ? 154.978 134.006 178.492 1.00 157.45 ? 48  U   A C5    1 
ATOM 705  C C6    . U   A 1 48  ? 153.688 134.093 178.155 1.00 156.99 ? 48  U   A C6    1 
ATOM 706  P P     . C   A 1 49  ? 149.591 138.026 179.277 1.00 147.58 ? 49  C   A P     1 
ATOM 707  O OP1   . C   A 1 49  ? 148.784 139.183 178.818 1.00 140.28 ? 49  C   A OP1   1 
ATOM 708  O OP2   . C   A 1 49  ? 151.005 138.221 179.679 1.00 141.99 ? 49  C   A OP2   1 
ATOM 709  O "O5'" . C   A 1 49  ? 148.821 137.358 180.502 1.00 139.30 ? 49  C   A "O5'" 1 
ATOM 710  C "C5'" . C   A 1 49  ? 148.434 138.143 181.623 1.00 138.85 ? 49  C   A "C5'" 1 
ATOM 711  C "C4'" . C   A 1 49  ? 148.584 137.387 182.920 1.00 140.71 ? 49  C   A "C4'" 1 
ATOM 712  O "O4'" . C   A 1 49  ? 149.480 136.262 182.733 1.00 142.10 ? 49  C   A "O4'" 1 
ATOM 713  C "C3'" . C   A 1 49  ? 149.198 138.165 184.076 1.00 139.53 ? 49  C   A "C3'" 1 
ATOM 714  O "O3'" . C   A 1 49  ? 148.259 138.982 184.753 1.00 140.22 ? 49  C   A "O3'" 1 
ATOM 715  C "C2'" . C   A 1 49  ? 149.787 137.066 184.948 1.00 137.54 ? 49  C   A "C2'" 1 
ATOM 716  O "O2'" . C   A 1 49  ? 148.778 136.458 185.739 1.00 137.75 ? 49  C   A "O2'" 1 
ATOM 717  C "C1'" . C   A 1 49  ? 150.250 136.056 183.898 1.00 139.01 ? 49  C   A "C1'" 1 
ATOM 718  N N1    . C   A 1 49  ? 151.676 136.227 183.548 1.00 137.41 ? 49  C   A N1    1 
ATOM 719  C C2    . C   A 1 49  ? 152.653 135.745 184.418 1.00 136.58 ? 49  C   A C2    1 
ATOM 720  O O2    . C   A 1 49  ? 152.321 135.194 185.476 1.00 133.53 ? 49  C   A O2    1 
ATOM 721  N N3    . C   A 1 49  ? 153.955 135.902 184.102 1.00 139.19 ? 49  C   A N3    1 
ATOM 722  C C4    . C   A 1 49  ? 154.294 136.500 182.960 1.00 140.55 ? 49  C   A C4    1 
ATOM 723  N N4    . C   A 1 49  ? 155.592 136.628 182.690 1.00 141.46 ? 49  C   A N4    1 
ATOM 724  C C5    . C   A 1 49  ? 153.322 136.996 182.049 1.00 140.18 ? 49  C   A C5    1 
ATOM 725  C C6    . C   A 1 49  ? 152.037 136.837 182.381 1.00 139.65 ? 49  C   A C6    1 
ATOM 726  P P     . U   A 1 50  ? 148.629 140.500 185.124 1.00 127.83 ? 50  U   A P     1 
ATOM 727  O OP1   . U   A 1 50  ? 147.368 141.223 185.423 1.00 125.07 ? 50  U   A OP1   1 
ATOM 728  O OP2   . U   A 1 50  ? 149.537 141.017 184.072 1.00 124.34 ? 50  U   A OP2   1 
ATOM 729  O "O5'" . U   A 1 50  ? 149.453 140.384 186.482 1.00 128.10 ? 50  U   A "O5'" 1 
ATOM 730  C "C5'" . U   A 1 50  ? 148.790 140.239 187.730 1.00 127.46 ? 50  U   A "C5'" 1 
ATOM 731  C "C4'" . U   A 1 50  ? 149.760 139.933 188.845 1.00 127.71 ? 50  U   A "C4'" 1 
ATOM 732  O "O4'" . U   A 1 50  ? 150.539 138.758 188.502 1.00 130.16 ? 50  U   A "O4'" 1 
ATOM 733  C "C3'" . U   A 1 50  ? 150.803 141.000 189.138 1.00 128.58 ? 50  U   A "C3'" 1 
ATOM 734  O "O3'" . U   A 1 50  ? 150.312 142.037 189.971 1.00 131.40 ? 50  U   A "O3'" 1 
ATOM 735  C "C2'" . U   A 1 50  ? 151.932 140.200 189.772 1.00 126.31 ? 50  U   A "C2'" 1 
ATOM 736  O "O2'" . U   A 1 50  ? 151.644 139.920 191.133 1.00 124.95 ? 50  U   A "O2'" 1 
ATOM 737  C "C1'" . U   A 1 50  ? 151.857 138.892 188.987 1.00 125.33 ? 50  U   A "C1'" 1 
ATOM 738  N N1    . U   A 1 50  ? 152.780 138.882 187.832 1.00 121.46 ? 50  U   A N1    1 
ATOM 739  C C2    . U   A 1 50  ? 154.123 138.704 188.076 1.00 122.24 ? 50  U   A C2    1 
ATOM 740  O O2    . U   A 1 50  ? 154.586 138.563 189.192 1.00 123.21 ? 50  U   A O2    1 
ATOM 741  N N3    . U   A 1 50  ? 154.916 138.710 186.962 1.00 123.75 ? 50  U   A N3    1 
ATOM 742  C C4    . U   A 1 50  ? 154.503 138.859 185.655 1.00 126.86 ? 50  U   A C4    1 
ATOM 743  O O4    . U   A 1 50  ? 155.330 138.836 184.746 1.00 130.19 ? 50  U   A O4    1 
ATOM 744  C C5    . U   A 1 50  ? 153.097 139.032 185.484 1.00 124.54 ? 50  U   A C5    1 
ATOM 745  C C6    . U   A 1 50  ? 152.304 139.036 186.555 1.00 123.90 ? 50  U   A C6    1 
ATOM 746  P P     . G   A 1 51  ? 150.961 143.506 189.908 1.00 132.49 ? 51  G   A P     1 
ATOM 747  O OP1   . G   A 1 51  ? 150.095 144.428 190.682 1.00 120.04 ? 51  G   A OP1   1 
ATOM 748  O OP2   . G   A 1 51  ? 151.267 143.804 188.489 1.00 123.43 ? 51  G   A OP2   1 
ATOM 749  O "O5'" . G   A 1 51  ? 152.342 143.360 190.691 1.00 124.31 ? 51  G   A "O5'" 1 
ATOM 750  C "C5'" . G   A 1 51  ? 152.365 143.099 192.086 1.00 118.84 ? 51  G   A "C5'" 1 
ATOM 751  C "C4'" . G   A 1 51  ? 153.770 142.878 192.594 1.00 118.91 ? 51  G   A "C4'" 1 
ATOM 752  O "O4'" . G   A 1 51  ? 154.366 141.732 191.931 1.00 120.80 ? 51  G   A "O4'" 1 
ATOM 753  C "C3'" . G   A 1 51  ? 154.761 144.004 192.348 1.00 117.22 ? 51  G   A "C3'" 1 
ATOM 754  O "O3'" . G   A 1 51  ? 154.647 145.056 193.290 1.00 116.98 ? 51  G   A "O3'" 1 
ATOM 755  C "C2'" . G   A 1 51  ? 156.099 143.281 192.404 1.00 116.13 ? 51  G   A "C2'" 1 
ATOM 756  O "O2'" . G   A 1 51  ? 156.473 143.029 193.748 1.00 114.41 ? 51  G   A "O2'" 1 
ATOM 757  C "C1'" . G   A 1 51  ? 155.748 141.948 191.743 1.00 117.17 ? 51  G   A "C1'" 1 
ATOM 758  N N9    . G   A 1 51  ? 156.019 141.968 190.294 1.00 119.77 ? 51  G   A N9    1 
ATOM 759  C C8    . G   A 1 51  ? 155.090 141.847 189.291 1.00 121.44 ? 51  G   A C8    1 
ATOM 760  N N7    . G   A 1 51  ? 155.611 141.904 188.098 1.00 119.30 ? 51  G   A N7    1 
ATOM 761  C C5    . G   A 1 51  ? 156.966 142.073 188.327 1.00 113.28 ? 51  G   A C5    1 
ATOM 762  C C6    . G   A 1 51  ? 158.032 142.204 187.409 1.00 112.86 ? 51  G   A C6    1 
ATOM 763  O O6    . G   A 1 51  ? 157.989 142.190 186.176 1.00 120.50 ? 51  G   A O6    1 
ATOM 764  N N1    . G   A 1 51  ? 159.245 142.356 188.059 1.00 108.78 ? 51  G   A N1    1 
ATOM 765  C C2    . G   A 1 51  ? 159.419 142.385 189.415 1.00 111.98 ? 51  G   A C2    1 
ATOM 766  N N2    . G   A 1 51  ? 160.677 142.545 189.845 1.00 114.65 ? 51  G   A N2    1 
ATOM 767  N N3    . G   A 1 51  ? 158.433 142.264 190.285 1.00 116.04 ? 51  G   A N3    1 
ATOM 768  C C4    . G   A 1 51  ? 157.240 142.109 189.676 1.00 114.67 ? 51  G   A C4    1 
ATOM 769  P P     . C   A 1 52  ? 154.831 146.584 192.829 1.00 118.23 ? 52  C   A P     1 
ATOM 770  O OP1   . C   A 1 52  ? 154.422 147.467 193.948 1.00 113.57 ? 52  C   A OP1   1 
ATOM 771  O OP2   . C   A 1 52  ? 154.178 146.745 191.508 1.00 117.57 ? 52  C   A OP2   1 
ATOM 772  O "O5'" . C   A 1 52  ? 156.404 146.740 192.640 1.00 117.57 ? 52  C   A "O5'" 1 
ATOM 773  C "C5'" . C   A 1 52  ? 157.285 146.611 193.746 1.00 112.09 ? 52  C   A "C5'" 1 
ATOM 774  C "C4'" . C   A 1 52  ? 158.722 146.491 193.304 1.00 111.71 ? 52  C   A "C4'" 1 
ATOM 775  O "O4'" . C   A 1 52  ? 158.874 145.328 192.446 1.00 113.76 ? 52  C   A "O4'" 1 
ATOM 776  C "C3'" . C   A 1 52  ? 159.264 147.641 192.470 1.00 108.50 ? 52  C   A "C3'" 1 
ATOM 777  O "O3'" . C   A 1 52  ? 159.678 148.750 193.247 1.00 112.96 ? 52  C   A "O3'" 1 
ATOM 778  C "C2'" . C   A 1 52  ? 160.402 146.983 191.708 1.00 110.27 ? 52  C   A "C2'" 1 
ATOM 779  O "O2'" . C   A 1 52  ? 161.536 146.824 192.545 1.00 110.84 ? 52  C   A "O2'" 1 
ATOM 780  C "C1'" . C   A 1 52  ? 159.813 145.600 191.429 1.00 111.45 ? 52  C   A "C1'" 1 
ATOM 781  N N1    . C   A 1 52  ? 159.114 145.542 190.123 1.00 113.77 ? 52  C   A N1    1 
ATOM 782  C C2    . C   A 1 52  ? 159.820 145.743 188.933 1.00 115.30 ? 52  C   A C2    1 
ATOM 783  O O2    . C   A 1 52  ? 161.035 145.975 188.991 1.00 119.60 ? 52  C   A O2    1 
ATOM 784  N N3    . C   A 1 52  ? 159.160 145.691 187.754 1.00 115.42 ? 52  C   A N3    1 
ATOM 785  C C4    . C   A 1 52  ? 157.853 145.438 187.728 1.00 114.46 ? 52  C   A C4    1 
ATOM 786  N N4    . C   A 1 52  ? 157.239 145.389 186.544 1.00 116.75 ? 52  C   A N4    1 
ATOM 787  C C5    . C   A 1 52  ? 157.110 145.224 188.920 1.00 111.16 ? 52  C   A C5    1 
ATOM 788  C C6    . C   A 1 52  ? 157.775 145.283 190.078 1.00 114.77 ? 52  C   A C6    1 
ATOM 789  P P     . G   A 1 53  ? 159.701 150.225 192.607 1.00 120.96 ? 53  G   A P     1 
ATOM 790  O OP1   . G   A 1 53  ? 160.034 151.194 193.677 1.00 119.59 ? 53  G   A OP1   1 
ATOM 791  O OP2   . G   A 1 53  ? 158.452 150.400 191.828 1.00 117.03 ? 53  G   A OP2   1 
ATOM 792  O "O5'" . G   A 1 53  ? 160.921 150.193 191.584 1.00 123.63 ? 53  G   A "O5'" 1 
ATOM 793  C "C5'" . G   A 1 53  ? 162.265 150.168 192.044 1.00 121.46 ? 53  G   A "C5'" 1 
ATOM 794  C "C4'" . G   A 1 53  ? 163.244 150.329 190.906 1.00 118.17 ? 53  G   A "C4'" 1 
ATOM 795  O "O4'" . G   A 1 53  ? 163.172 149.176 190.030 1.00 117.09 ? 53  G   A "O4'" 1 
ATOM 796  C "C3'" . G   A 1 53  ? 163.001 151.517 189.987 1.00 118.25 ? 53  G   A "C3'" 1 
ATOM 797  O "O3'" . G   A 1 53  ? 163.551 152.718 190.498 1.00 120.09 ? 53  G   A "O3'" 1 
ATOM 798  C "C2'" . G   A 1 53  ? 163.639 151.071 188.680 1.00 118.86 ? 53  G   A "C2'" 1 
ATOM 799  O "O2'" . G   A 1 53  ? 165.047 151.245 188.727 1.00 117.24 ? 53  G   A "O2'" 1 
ATOM 800  C "C1'" . G   A 1 53  ? 163.341 149.574 188.688 1.00 117.02 ? 53  G   A "C1'" 1 
ATOM 801  N N9    . G   A 1 53  ? 162.108 149.236 187.953 1.00 119.55 ? 53  G   A N9    1 
ATOM 802  C C8    . G   A 1 53  ? 160.963 148.751 188.523 1.00 123.94 ? 53  G   A C8    1 
ATOM 803  N N7    . G   A 1 53  ? 160.016 148.505 187.667 1.00 122.67 ? 53  G   A N7    1 
ATOM 804  C C5    . G   A 1 53  ? 160.566 148.857 186.450 1.00 119.80 ? 53  G   A C5    1 
ATOM 805  C C6    . G   A 1 53  ? 159.993 148.810 185.159 1.00 119.51 ? 53  G   A C6    1 
ATOM 806  O O6    . G   A 1 53  ? 158.859 148.441 184.833 1.00 123.71 ? 53  G   A O6    1 
ATOM 807  N N1    . G   A 1 53  ? 160.885 149.260 184.200 1.00 114.76 ? 53  G   A N1    1 
ATOM 808  C C2    . G   A 1 53  ? 162.160 149.694 184.448 1.00 115.71 ? 53  G   A C2    1 
ATOM 809  N N2    . G   A 1 53  ? 162.859 150.086 183.378 1.00 114.80 ? 53  G   A N2    1 
ATOM 810  N N3    . G   A 1 53  ? 162.709 149.741 185.648 1.00 119.71 ? 53  G   A N3    1 
ATOM 811  C C4    . G   A 1 53  ? 161.861 149.305 186.601 1.00 119.60 ? 53  G   A C4    1 
ATOM 812  P P     . U   A 1 54  ? 162.940 154.137 190.064 1.00 136.01 ? 54  U   A P     1 
ATOM 813  O OP1   . U   A 1 54  ? 163.648 155.196 190.824 1.00 129.73 ? 54  U   A OP1   1 
ATOM 814  O OP2   . U   A 1 54  ? 161.461 154.041 190.139 1.00 135.24 ? 54  U   A OP2   1 
ATOM 815  O "O5'" . U   A 1 54  ? 163.346 154.280 188.532 1.00 132.04 ? 54  U   A "O5'" 1 
ATOM 816  C "C5'" . U   A 1 54  ? 164.699 154.461 188.141 1.00 132.46 ? 54  U   A "C5'" 1 
ATOM 817  C "C4'" . U   A 1 54  ? 164.796 154.773 186.670 1.00 132.94 ? 54  U   A "C4'" 1 
ATOM 818  O "O4'" . U   A 1 54  ? 164.451 153.593 185.900 1.00 132.41 ? 54  U   A "O4'" 1 
ATOM 819  C "C3'" . U   A 1 54  ? 163.835 155.842 186.174 1.00 136.05 ? 54  U   A "C3'" 1 
ATOM 820  O "O3'" . U   A 1 54  ? 164.332 157.152 186.384 1.00 135.22 ? 54  U   A "O3'" 1 
ATOM 821  C "C2'" . U   A 1 54  ? 163.647 155.481 184.707 1.00 135.02 ? 54  U   A "C2'" 1 
ATOM 822  O "O2'" . U   A 1 54  ? 164.739 155.954 183.934 1.00 135.13 ? 54  U   A "O2'" 1 
ATOM 823  C "C1'" . U   A 1 54  ? 163.714 153.957 184.754 1.00 131.51 ? 54  U   A "C1'" 1 
ATOM 824  N N1    . U   A 1 54  ? 162.381 153.313 184.840 1.00 131.30 ? 54  U   A N1    1 
ATOM 825  C C2    . U   A 1 54  ? 161.637 153.131 183.689 1.00 129.85 ? 54  U   A C2    1 
ATOM 826  O O2    . U   A 1 54  ? 162.008 153.507 182.591 1.00 129.30 ? 54  U   A O2    1 
ATOM 827  N N3    . U   A 1 54  ? 160.426 152.507 183.875 1.00 129.68 ? 54  U   A N3    1 
ATOM 828  C C4    . U   A 1 54  ? 159.900 152.046 185.063 1.00 128.56 ? 54  U   A C4    1 
ATOM 829  O O4    . U   A 1 54  ? 158.798 151.498 185.087 1.00 130.04 ? 54  U   A O4    1 
ATOM 830  C C5    . U   A 1 54  ? 160.732 152.262 186.200 1.00 129.69 ? 54  U   A C5    1 
ATOM 831  C C6    . U   A 1 54  ? 161.912 152.864 186.050 1.00 133.55 ? 54  U   A C6    1 
ATOM 832  P P     . G   A 1 55  ? 163.529 158.425 185.828 1.00 145.27 ? 55  G   A P     1 
ATOM 833  O OP1   . G   A 1 55  ? 164.043 159.635 186.517 1.00 135.97 ? 55  G   A OP1   1 
ATOM 834  O OP2   . G   A 1 55  ? 162.079 158.116 185.877 1.00 140.00 ? 55  G   A OP2   1 
ATOM 835  O "O5'" . G   A 1 55  ? 163.970 158.512 184.301 1.00 140.99 ? 55  G   A "O5'" 1 
ATOM 836  C "C5'" . G   A 1 55  ? 163.222 159.285 183.373 1.00 137.76 ? 55  G   A "C5'" 1 
ATOM 837  C "C4'" . G   A 1 55  ? 163.090 158.592 182.040 1.00 135.72 ? 55  G   A "C4'" 1 
ATOM 838  O "O4'" . G   A 1 55  ? 162.511 157.269 182.233 1.00 134.35 ? 55  G   A "O4'" 1 
ATOM 839  C "C3'" . G   A 1 55  ? 162.182 159.309 181.047 1.00 137.52 ? 55  G   A "C3'" 1 
ATOM 840  O "O3'" . G   A 1 55  ? 162.624 159.039 179.720 1.00 140.05 ? 55  G   A "O3'" 1 
ATOM 841  C "C2'" . G   A 1 55  ? 160.850 158.605 181.265 1.00 136.88 ? 55  G   A "C2'" 1 
ATOM 842  O "O2'" . G   A 1 55  ? 159.951 158.703 180.182 1.00 140.26 ? 55  G   A "O2'" 1 
ATOM 843  C "C1'" . G   A 1 55  ? 161.310 157.169 181.493 1.00 135.19 ? 55  G   A "C1'" 1 
ATOM 844  N N9    . G   A 1 55  ? 160.359 156.347 182.245 1.00 134.66 ? 55  G   A N9    1 
ATOM 845  C C8    . G   A 1 55  ? 160.390 156.061 183.586 1.00 133.86 ? 55  G   A C8    1 
ATOM 846  N N7    . G   A 1 55  ? 159.408 155.295 183.971 1.00 134.53 ? 55  G   A N7    1 
ATOM 847  C C5    . G   A 1 55  ? 158.685 155.058 182.812 1.00 135.03 ? 55  G   A C5    1 
ATOM 848  C C6    . G   A 1 55  ? 157.510 154.295 182.606 1.00 135.60 ? 55  G   A C6    1 
ATOM 849  O O6    . G   A 1 55  ? 156.854 153.653 183.433 1.00 138.22 ? 55  G   A O6    1 
ATOM 850  N N1    . G   A 1 55  ? 157.105 154.316 181.278 1.00 133.40 ? 55  G   A N1    1 
ATOM 851  C C2    . G   A 1 55  ? 157.749 154.988 180.271 1.00 133.52 ? 55  G   A C2    1 
ATOM 852  N N2    . G   A 1 55  ? 157.199 154.888 179.052 1.00 134.13 ? 55  G   A N2    1 
ATOM 853  N N3    . G   A 1 55  ? 158.846 155.706 180.449 1.00 134.84 ? 55  G   A N3    1 
ATOM 854  C C4    . G   A 1 55  ? 159.260 155.693 181.735 1.00 135.45 ? 55  G   A C4    1 
ATOM 855  P P     . C   A 1 56  ? 163.872 159.813 179.065 1.00 146.72 ? 56  C   A P     1 
ATOM 856  O OP1   . C   A 1 56  ? 164.916 160.083 180.083 1.00 140.37 ? 56  C   A OP1   1 
ATOM 857  O OP2   . C   A 1 56  ? 163.339 160.933 178.251 1.00 142.09 ? 56  C   A OP2   1 
ATOM 858  O "O5'" . C   A 1 56  ? 164.446 158.722 178.065 1.00 145.34 ? 56  C   A "O5'" 1 
ATOM 859  C "C5'" . C   A 1 56  ? 163.639 157.611 177.713 1.00 143.67 ? 56  C   A "C5'" 1 
ATOM 860  C "C4'" . C   A 1 56  ? 164.467 156.434 177.278 1.00 142.38 ? 56  C   A "C4'" 1 
ATOM 861  O "O4'" . C   A 1 56  ? 165.101 156.716 176.005 1.00 141.89 ? 56  C   A "O4'" 1 
ATOM 862  C "C3'" . C   A 1 56  ? 165.627 156.060 178.180 1.00 140.16 ? 56  C   A "C3'" 1 
ATOM 863  O "O3'" . C   A 1 56  ? 165.235 155.332 179.328 1.00 138.28 ? 56  C   A "O3'" 1 
ATOM 864  C "C2'" . C   A 1 56  ? 166.522 155.271 177.240 1.00 141.81 ? 56  C   A "C2'" 1 
ATOM 865  O "O2'" . C   A 1 56  ? 166.012 153.961 177.051 1.00 143.27 ? 56  C   A "O2'" 1 
ATOM 866  C "C1'" . C   A 1 56  ? 166.343 156.049 175.937 1.00 141.32 ? 56  C   A "C1'" 1 
ATOM 867  N N1    . C   A 1 56  ? 167.420 157.044 175.737 1.00 139.96 ? 56  C   A N1    1 
ATOM 868  C C2    . C   A 1 56  ? 168.660 156.562 175.326 1.00 141.62 ? 56  C   A C2    1 
ATOM 869  O O2    . C   A 1 56  ? 168.791 155.345 175.149 1.00 143.14 ? 56  C   A O2    1 
ATOM 870  N N3    . C   A 1 56  ? 169.682 157.419 175.129 1.00 143.21 ? 56  C   A N3    1 
ATOM 871  C C4    . C   A 1 56  ? 169.495 158.722 175.332 1.00 141.58 ? 56  C   A C4    1 
ATOM 872  N N4    . C   A 1 56  ? 170.536 159.530 175.124 1.00 141.47 ? 56  C   A N4    1 
ATOM 873  C C5    . C   A 1 56  ? 168.240 159.248 175.754 1.00 140.83 ? 56  C   A C5    1 
ATOM 874  C C6    . C   A 1 56  ? 167.236 158.381 175.943 1.00 141.14 ? 56  C   A C6    1 
ATOM 875  P P     . G   A 1 57  ? 166.153 155.365 180.644 1.00 149.86 ? 57  G   A P     1 
ATOM 876  O OP1   . G   A 1 57  ? 165.392 154.746 181.757 1.00 154.86 ? 57  G   A OP1   1 
ATOM 877  O OP2   . G   A 1 57  ? 166.672 156.747 180.787 1.00 147.96 ? 57  G   A OP2   1 
ATOM 878  O "O5'" . G   A 1 57  ? 167.377 154.411 180.288 1.00 147.01 ? 57  G   A "O5'" 1 
ATOM 879  C "C5'" . G   A 1 57  ? 167.162 153.041 179.983 1.00 147.43 ? 57  G   A "C5'" 1 
ATOM 880  C "C4'" . G   A 1 57  ? 168.367 152.417 179.323 1.00 147.28 ? 57  G   A "C4'" 1 
ATOM 881  O "O4'" . G   A 1 57  ? 168.718 153.156 178.125 1.00 149.21 ? 57  G   A "O4'" 1 
ATOM 882  C "C3'" . G   A 1 57  ? 169.649 152.413 180.135 1.00 147.77 ? 57  G   A "C3'" 1 
ATOM 883  O "O3'" . G   A 1 57  ? 169.689 151.378 181.100 1.00 146.34 ? 57  G   A "O3'" 1 
ATOM 884  C "C2'" . G   A 1 57  ? 170.718 152.286 179.059 1.00 149.51 ? 57  G   A "C2'" 1 
ATOM 885  O "O2'" . G   A 1 57  ? 170.810 150.946 178.601 1.00 151.33 ? 57  G   A "O2'" 1 
ATOM 886  C "C1'" . G   A 1 57  ? 170.118 153.135 177.942 1.00 148.34 ? 57  G   A "C1'" 1 
ATOM 887  N N9    . G   A 1 57  ? 170.623 154.520 177.980 1.00 147.32 ? 57  G   A N9    1 
ATOM 888  C C8    . G   A 1 57  ? 169.999 155.623 178.506 1.00 149.47 ? 57  G   A C8    1 
ATOM 889  N N7    . G   A 1 57  ? 170.706 156.714 178.391 1.00 148.36 ? 57  G   A N7    1 
ATOM 890  C C5    . G   A 1 57  ? 171.867 156.305 177.754 1.00 148.00 ? 57  G   A C5    1 
ATOM 891  C C6    . G   A 1 57  ? 173.009 157.046 177.360 1.00 149.82 ? 57  G   A C6    1 
ATOM 892  O O6    . G   A 1 57  ? 173.230 158.255 177.504 1.00 149.15 ? 57  G   A O6    1 
ATOM 893  N N1    . G   A 1 57  ? 173.955 156.234 176.746 1.00 151.79 ? 57  G   A N1    1 
ATOM 894  C C2    . G   A 1 57  ? 173.820 154.885 176.533 1.00 151.18 ? 57  G   A C2    1 
ATOM 895  N N2    . G   A 1 57  ? 174.832 154.256 175.923 1.00 151.78 ? 57  G   A N2    1 
ATOM 896  N N3    . G   A 1 57  ? 172.760 154.185 176.896 1.00 147.90 ? 57  G   A N3    1 
ATOM 897  C C4    . G   A 1 57  ? 171.831 154.954 177.496 1.00 146.98 ? 57  G   A C4    1 
ATOM 898  P P     . G   A 1 58  ? 170.693 151.485 182.347 1.00 145.28 ? 58  G   A P     1 
ATOM 899  O OP1   . G   A 1 58  ? 170.357 150.407 183.309 1.00 145.87 ? 58  G   A OP1   1 
ATOM 900  O OP2   . G   A 1 58  ? 170.701 152.898 182.801 1.00 146.72 ? 58  G   A OP2   1 
ATOM 901  O "O5'" . G   A 1 58  ? 172.119 151.155 181.718 1.00 147.32 ? 58  G   A "O5'" 1 
ATOM 902  C "C5'" . G   A 1 58  ? 173.313 151.470 182.418 1.00 147.11 ? 58  G   A "C5'" 1 
ATOM 903  C "C4'" . G   A 1 58  ? 174.534 151.184 181.583 1.00 146.13 ? 58  G   A "C4'" 1 
ATOM 904  O "O4'" . G   A 1 58  ? 174.418 151.845 180.299 1.00 146.01 ? 58  G   A "O4'" 1 
ATOM 905  C "C3'" . G   A 1 58  ? 175.851 151.692 182.145 1.00 148.19 ? 58  G   A "C3'" 1 
ATOM 906  O "O3'" . G   A 1 58  ? 176.399 150.825 183.121 1.00 150.52 ? 58  G   A "O3'" 1 
ATOM 907  C "C2'" . G   A 1 58  ? 176.718 151.826 180.901 1.00 147.37 ? 58  G   A "C2'" 1 
ATOM 908  O "O2'" . G   A 1 58  ? 177.236 150.562 180.515 1.00 146.02 ? 58  G   A "O2'" 1 
ATOM 909  C "C1'" . G   A 1 58  ? 175.690 152.265 179.857 1.00 146.66 ? 58  G   A "C1'" 1 
ATOM 910  N N9    . G   A 1 58  ? 175.662 153.727 179.657 1.00 147.97 ? 58  G   A N9    1 
ATOM 911  C C8    . G   A 1 58  ? 174.550 154.528 179.713 1.00 146.55 ? 58  G   A C8    1 
ATOM 912  N N7    . G   A 1 58  ? 174.808 155.784 179.482 1.00 145.24 ? 58  G   A N7    1 
ATOM 913  C C5    . G   A 1 58  ? 176.173 155.818 179.247 1.00 146.93 ? 58  G   A C5    1 
ATOM 914  C C6    . G   A 1 58  ? 177.022 156.913 178.940 1.00 148.11 ? 58  G   A C6    1 
ATOM 915  O O6    . G   A 1 58  ? 176.732 158.109 178.809 1.00 148.84 ? 58  G   A O6    1 
ATOM 916  N N1    . G   A 1 58  ? 178.340 156.501 178.781 1.00 149.43 ? 58  G   A N1    1 
ATOM 917  C C2    . G   A 1 58  ? 178.786 155.210 178.902 1.00 147.90 ? 58  G   A C2    1 
ATOM 918  N N2    . G   A 1 58  ? 180.097 155.016 178.711 1.00 146.47 ? 58  G   A N2    1 
ATOM 919  N N3    . G   A 1 58  ? 178.006 154.183 179.186 1.00 147.57 ? 58  G   A N3    1 
ATOM 920  C C4    . G   A 1 58  ? 176.718 154.554 179.345 1.00 148.26 ? 58  G   A C4    1 
ATOM 921  P P     . A   A 1 59  ? 177.163 151.427 184.398 1.00 148.99 ? 59  A   A P     1 
ATOM 922  O OP1   . A   A 1 59  ? 177.505 150.300 185.300 1.00 140.36 ? 59  A   A OP1   1 
ATOM 923  O OP2   . A   A 1 59  ? 176.369 152.571 184.913 1.00 143.83 ? 59  A   A OP2   1 
ATOM 924  O "O5'" . A   A 1 59  ? 178.518 152.007 183.799 1.00 139.83 ? 59  A   A "O5'" 1 
ATOM 925  C "C5'" . A   A 1 59  ? 179.485 151.151 183.208 1.00 136.66 ? 59  A   A "C5'" 1 
ATOM 926  C "C4'" . A   A 1 59  ? 180.688 151.934 182.754 1.00 134.49 ? 59  A   A "C4'" 1 
ATOM 927  O "O4'" . A   A 1 59  ? 180.311 152.801 181.654 1.00 138.56 ? 59  A   A "O4'" 1 
ATOM 928  C "C3'" . A   A 1 59  ? 181.276 152.876 183.791 1.00 133.90 ? 59  A   A "C3'" 1 
ATOM 929  O "O3'" . A   A 1 59  ? 182.165 152.223 184.679 1.00 136.70 ? 59  A   A "O3'" 1 
ATOM 930  C "C2'" . A   A 1 59  ? 181.944 153.946 182.941 1.00 138.18 ? 59  A   A "C2'" 1 
ATOM 931  O "O2'" . A   A 1 59  ? 183.201 153.490 182.463 1.00 139.44 ? 59  A   A "O2'" 1 
ATOM 932  C "C1'" . A   A 1 59  ? 180.984 154.036 181.757 1.00 139.17 ? 59  A   A "C1'" 1 
ATOM 933  N N9    . A   A 1 59  ? 179.971 155.098 181.915 1.00 137.48 ? 59  A   A N9    1 
ATOM 934  C C8    . A   A 1 59  ? 178.644 154.930 182.218 1.00 136.58 ? 59  A   A C8    1 
ATOM 935  N N7    . A   A 1 59  ? 177.965 156.047 182.275 1.00 135.73 ? 59  A   A N7    1 
ATOM 936  C C5    . A   A 1 59  ? 178.906 157.020 181.984 1.00 136.03 ? 59  A   A C5    1 
ATOM 937  C C6    . A   A 1 59  ? 178.815 158.419 181.888 1.00 135.89 ? 59  A   A C6    1 
ATOM 938  N N6    . A   A 1 59  ? 177.688 159.104 182.082 1.00 133.60 ? 59  A   A N6    1 
ATOM 939  N N1    . A   A 1 59  ? 179.937 159.102 181.581 1.00 138.76 ? 59  A   A N1    1 
ATOM 940  C C2    . A   A 1 59  ? 181.068 158.414 181.384 1.00 139.94 ? 59  A   A C2    1 
ATOM 941  N N3    . A   A 1 59  ? 181.278 157.101 181.449 1.00 139.53 ? 59  A   A N3    1 
ATOM 942  C C4    . A   A 1 59  ? 180.144 156.451 181.756 1.00 137.81 ? 59  A   A C4    1 
ATOM 943  P P     . A   A 1 60  ? 182.370 152.780 186.170 1.00 143.27 ? 60  A   A P     1 
ATOM 944  O OP1   . A   A 1 60  ? 183.080 151.741 186.958 1.00 134.60 ? 60  A   A OP1   1 
ATOM 945  O OP2   . A   A 1 60  ? 181.070 153.314 186.646 1.00 134.64 ? 60  A   A OP2   1 
ATOM 946  O "O5'" . A   A 1 60  ? 183.356 154.016 185.987 1.00 133.37 ? 60  A   A "O5'" 1 
ATOM 947  C "C5'" . A   A 1 60  ? 184.671 153.837 185.483 1.00 128.70 ? 60  A   A "C5'" 1 
ATOM 948  C "C4'" . A   A 1 60  ? 185.335 155.165 185.241 1.00 128.36 ? 60  A   A "C4'" 1 
ATOM 949  O "O4'" . A   A 1 60  ? 184.629 155.867 184.188 1.00 130.82 ? 60  A   A "O4'" 1 
ATOM 950  C "C3'" . A   A 1 60  ? 185.312 156.126 186.418 1.00 126.96 ? 60  A   A "C3'" 1 
ATOM 951  O "O3'" . A   A 1 60  ? 186.375 155.890 187.325 1.00 127.77 ? 60  A   A "O3'" 1 
ATOM 952  C "C2'" . A   A 1 60  ? 185.376 157.493 185.750 1.00 128.24 ? 60  A   A "C2'" 1 
ATOM 953  O "O2'" . A   A 1 60  ? 186.713 157.819 185.403 1.00 127.92 ? 60  A   A "O2'" 1 
ATOM 954  C "C1'" . A   A 1 60  ? 184.589 157.248 184.464 1.00 132.01 ? 60  A   A "C1'" 1 
ATOM 955  N N9    . A   A 1 60  ? 183.175 157.657 184.557 1.00 132.50 ? 60  A   A N9    1 
ATOM 956  C C8    . A   A 1 60  ? 182.093 156.823 184.656 1.00 130.58 ? 60  A   A C8    1 
ATOM 957  N N7    . A   A 1 60  ? 180.942 157.443 184.695 1.00 129.07 ? 60  A   A N7    1 
ATOM 958  C C5    . A   A 1 60  ? 181.290 158.781 184.609 1.00 128.61 ? 60  A   A C5    1 
ATOM 959  C C6    . A   A 1 60  ? 180.515 159.948 184.599 1.00 124.77 ? 60  A   A C6    1 
ATOM 960  N N6    . A   A 1 60  ? 179.186 159.939 184.682 1.00 122.55 ? 60  A   A N6    1 
ATOM 961  N N1    . A   A 1 60  ? 181.157 161.131 184.502 1.00 126.83 ? 60  A   A N1    1 
ATOM 962  C C2    . A   A 1 60  ? 182.492 161.123 184.420 1.00 130.73 ? 60  A   A C2    1 
ATOM 963  N N3    . A   A 1 60  ? 183.332 160.089 184.419 1.00 133.13 ? 60  A   A N3    1 
ATOM 964  C C4    . A   A 1 60  ? 182.660 158.930 184.515 1.00 132.29 ? 60  A   A C4    1 
ATOM 965  P P     . U   A 1 61  ? 186.199 156.216 188.887 1.00 129.04 ? 61  U   A P     1 
ATOM 966  O OP1   . U   A 1 61  ? 187.441 155.797 189.583 1.00 122.24 ? 61  U   A OP1   1 
ATOM 967  O OP2   . U   A 1 61  ? 184.889 155.682 189.331 1.00 128.63 ? 61  U   A OP2   1 
ATOM 968  O "O5'" . U   A 1 61  ? 186.134 157.804 188.942 1.00 119.41 ? 61  U   A "O5'" 1 
ATOM 969  C "C5'" . U   A 1 61  ? 187.249 158.586 188.551 1.00 119.58 ? 61  U   A "C5'" 1 
ATOM 970  C "C4'" . U   A 1 61  ? 186.884 160.041 188.438 1.00 119.54 ? 61  U   A "C4'" 1 
ATOM 971  O "O4'" . U   A 1 61  ? 185.906 160.226 187.386 1.00 120.29 ? 61  U   A "O4'" 1 
ATOM 972  C "C3'" . U   A 1 61  ? 186.228 160.652 189.662 1.00 115.45 ? 61  U   A "C3'" 1 
ATOM 973  O "O3'" . U   A 1 61  ? 187.170 161.015 190.654 1.00 120.19 ? 61  U   A "O3'" 1 
ATOM 974  C "C2'" . U   A 1 61  ? 185.467 161.834 189.078 1.00 114.71 ? 61  U   A "C2'" 1 
ATOM 975  O "O2'" . U   A 1 61  ? 186.339 162.929 188.850 1.00 115.68 ? 61  U   A "O2'" 1 
ATOM 976  C "C1'" . U   A 1 61  ? 185.030 161.279 187.723 1.00 118.27 ? 61  U   A "C1'" 1 
ATOM 977  N N1    . U   A 1 61  ? 183.648 160.755 187.744 1.00 118.56 ? 61  U   A N1    1 
ATOM 978  C C2    . U   A 1 61  ? 182.613 161.667 187.743 1.00 119.45 ? 61  U   A C2    1 
ATOM 979  O O2    . U   A 1 61  ? 182.787 162.873 187.737 1.00 117.93 ? 61  U   A O2    1 
ATOM 980  N N3    . U   A 1 61  ? 181.358 161.115 187.756 1.00 121.44 ? 61  U   A N3    1 
ATOM 981  C C4    . U   A 1 61  ? 181.046 159.772 187.766 1.00 121.68 ? 61  U   A C4    1 
ATOM 982  O O4    . U   A 1 61  ? 179.867 159.419 187.775 1.00 122.66 ? 61  U   A O4    1 
ATOM 983  C C5    . U   A 1 61  ? 182.173 158.895 187.762 1.00 120.36 ? 61  U   A C5    1 
ATOM 984  C C6    . U   A 1 61  ? 183.404 159.407 187.750 1.00 119.05 ? 61  U   A C6    1 
ATOM 985  P P     . C   A 1 62  ? 186.760 161.000 192.205 1.00 119.37 ? 62  C   A P     1 
ATOM 986  O OP1   . C   A 1 62  ? 188.007 161.071 193.006 1.00 108.69 ? 62  C   A OP1   1 
ATOM 987  O OP2   . C   A 1 62  ? 185.808 159.883 192.424 1.00 110.51 ? 62  C   A OP2   1 
ATOM 988  O "O5'" . C   A 1 62  ? 185.976 162.369 192.399 1.00 109.42 ? 62  C   A "O5'" 1 
ATOM 989  C "C5'" . C   A 1 62  ? 186.558 163.593 191.987 1.00 106.15 ? 62  C   A "C5'" 1 
ATOM 990  C "C4'" . C   A 1 62  ? 185.558 164.715 192.018 1.00 106.04 ? 62  C   A "C4'" 1 
ATOM 991  O "O4'" . C   A 1 62  ? 184.604 164.569 190.936 1.00 104.14 ? 62  C   A "O4'" 1 
ATOM 992  C "C3'" . C   A 1 62  ? 184.692 164.785 193.259 1.00 108.08 ? 62  C   A "C3'" 1 
ATOM 993  O "O3'" . C   A 1 62  ? 185.362 165.376 194.357 1.00 113.60 ? 62  C   A "O3'" 1 
ATOM 994  C "C2'" . C   A 1 62  ? 183.479 165.567 192.773 1.00 102.89 ? 62  C   A "C2'" 1 
ATOM 995  O "O2'" . C   A 1 62  ? 183.760 166.957 192.721 1.00 101.86 ? 62  C   A "O2'" 1 
ATOM 996  C "C1'" . C   A 1 62  ? 183.339 165.047 191.342 1.00 102.37 ? 62  C   A "C1'" 1 
ATOM 997  N N1    . C   A 1 62  ? 182.366 163.938 191.248 1.00 104.82 ? 62  C   A N1    1 
ATOM 998  C C2    . C   A 1 62  ? 181.001 164.225 191.245 1.00 107.32 ? 62  C   A C2    1 
ATOM 999  O O2    . C   A 1 62  ? 180.641 165.407 191.321 1.00 109.64 ? 62  C   A O2    1 
ATOM 1000 N N3    . C   A 1 62  ? 180.119 163.205 191.161 1.00 107.53 ? 62  C   A N3    1 
ATOM 1001 C C4    . C   A 1 62  ? 180.559 161.951 191.081 1.00 107.13 ? 62  C   A C4    1 
ATOM 1002 N N4    . C   A 1 62  ? 179.665 160.966 190.997 1.00 110.89 ? 62  C   A N4    1 
ATOM 1003 C C5    . C   A 1 62  ? 181.943 161.634 191.080 1.00 106.96 ? 62  C   A C5    1 
ATOM 1004 C C6    . C   A 1 62  ? 182.802 162.650 191.166 1.00 107.18 ? 62  C   A C6    1 
ATOM 1005 P P     . G   A 1 63  ? 184.945 164.990 195.857 1.00 115.69 ? 63  G   A P     1 
ATOM 1006 O OP1   . G   A 1 63  ? 185.929 165.593 196.788 1.00 107.99 ? 63  G   A OP1   1 
ATOM 1007 O OP2   . G   A 1 63  ? 184.682 163.530 195.906 1.00 106.50 ? 63  G   A OP2   1 
ATOM 1008 O "O5'" . G   A 1 63  ? 183.561 165.743 196.059 1.00 107.22 ? 63  G   A "O5'" 1 
ATOM 1009 C "C5'" . G   A 1 63  ? 182.577 165.226 196.936 1.00 109.40 ? 63  G   A "C5'" 1 
ATOM 1010 C "C4'" . G   A 1 63  ? 181.195 165.640 196.509 1.00 106.58 ? 63  G   A "C4'" 1 
ATOM 1011 O "O4'" . G   A 1 63  ? 180.921 165.139 195.177 1.00 108.62 ? 63  G   A "O4'" 1 
ATOM 1012 C "C3'" . G   A 1 63  ? 180.055 165.092 197.345 1.00 105.02 ? 63  G   A "C3'" 1 
ATOM 1013 O "O3'" . G   A 1 63  ? 179.854 165.819 198.543 1.00 105.80 ? 63  G   A "O3'" 1 
ATOM 1014 C "C2'" . G   A 1 63  ? 178.881 165.160 196.384 1.00 101.62 ? 63  G   A "C2'" 1 
ATOM 1015 O "O2'" . G   A 1 63  ? 178.395 166.486 196.292 1.00 99.25  ? 63  G   A "O2'" 1 
ATOM 1016 C "C1'" . G   A 1 63  ? 179.555 164.810 195.061 1.00 98.71  ? 63  G   A "C1'" 1 
ATOM 1017 N N9    . G   A 1 63  ? 179.438 163.378 194.735 1.00 100.86 ? 63  G   A N9    1 
ATOM 1018 C C8    . G   A 1 63  ? 180.455 162.471 194.578 1.00 101.18 ? 63  G   A C8    1 
ATOM 1019 N N7    . G   A 1 63  ? 180.029 161.275 194.277 1.00 104.39 ? 63  G   A N7    1 
ATOM 1020 C C5    . G   A 1 63  ? 178.649 161.404 194.231 1.00 107.19 ? 63  G   A C5    1 
ATOM 1021 C C6    . G   A 1 63  ? 177.643 160.447 193.954 1.00 102.79 ? 63  G   A C6    1 
ATOM 1022 O O6    . G   A 1 63  ? 177.776 159.249 193.684 1.00 101.97 ? 63  G   A O6    1 
ATOM 1023 N N1    . G   A 1 63  ? 176.372 161.007 194.012 1.00 101.44 ? 63  G   A N1    1 
ATOM 1024 C C2    . G   A 1 63  ? 176.097 162.319 194.306 1.00 103.66 ? 63  G   A C2    1 
ATOM 1025 N N2    . G   A 1 63  ? 174.806 162.676 194.314 1.00 105.35 ? 63  G   A N2    1 
ATOM 1026 N N3    . G   A 1 63  ? 177.026 163.221 194.560 1.00 106.20 ? 63  G   A N3    1 
ATOM 1027 C C4    . G   A 1 63  ? 178.269 162.697 194.507 1.00 106.58 ? 63  G   A C4    1 
ATOM 1028 P P     . A   A 1 64  ? 179.717 165.039 199.938 1.00 101.58 ? 64  A   A P     1 
ATOM 1029 O OP1   . A   A 1 64  ? 179.636 166.051 201.018 1.00 97.86  ? 64  A   A OP1   1 
ATOM 1030 O OP2   . A   A 1 64  ? 180.763 163.989 199.984 1.00 102.71 ? 64  A   A OP2   1 
ATOM 1031 O "O5'" . A   A 1 64  ? 178.304 164.316 199.827 1.00 103.15 ? 64  A   A "O5'" 1 
ATOM 1032 C "C5'" . A   A 1 64  ? 177.134 165.064 199.542 1.00 98.73  ? 64  A   A "C5'" 1 
ATOM 1033 C "C4'" . A   A 1 64  ? 175.976 164.171 199.181 1.00 90.41  ? 64  A   A "C4'" 1 
ATOM 1034 O "O4'" . A   A 1 64  ? 176.236 163.499 197.923 1.00 88.96  ? 64  A   A "O4'" 1 
ATOM 1035 C "C3'" . A   A 1 64  ? 175.684 163.035 200.141 1.00 92.42  ? 64  A   A "C3'" 1 
ATOM 1036 O "O3'" . A   A 1 64  ? 174.982 163.454 201.298 1.00 102.62 ? 64  A   A "O3'" 1 
ATOM 1037 C "C2'" . A   A 1 64  ? 174.905 162.067 199.264 1.00 96.55  ? 64  A   A "C2'" 1 
ATOM 1038 O "O2'" . A   A 1 64  ? 173.572 162.518 199.084 1.00 103.50 ? 64  A   A "O2'" 1 
ATOM 1039 C "C1'" . A   A 1 64  ? 175.641 162.219 197.936 1.00 88.50  ? 64  A   A "C1'" 1 
ATOM 1040 N N9    . A   A 1 64  ? 176.698 161.208 197.788 1.00 91.94  ? 64  A   A N9    1 
ATOM 1041 C C8    . A   A 1 64  ? 178.042 161.355 198.000 1.00 97.40  ? 64  A   A C8    1 
ATOM 1042 N N7    . A   A 1 64  ? 178.729 160.259 197.788 1.00 96.54  ? 64  A   A N7    1 
ATOM 1043 C C5    . A   A 1 64  ? 177.768 159.332 197.414 1.00 99.43  ? 64  A   A C5    1 
ATOM 1044 C C6    . A   A 1 64  ? 177.848 157.978 197.055 1.00 104.25 ? 64  A   A C6    1 
ATOM 1045 N N6    . A   A 1 64  ? 178.990 157.291 197.011 1.00 104.37 ? 64  A   A N6    1 
ATOM 1046 N N1    . A   A 1 64  ? 176.702 157.343 196.738 1.00 105.22 ? 64  A   A N1    1 
ATOM 1047 C C2    . A   A 1 64  ? 175.557 158.032 196.782 1.00 104.12 ? 64  A   A C2    1 
ATOM 1048 N N3    . A   A 1 64  ? 175.355 159.306 197.104 1.00 105.52 ? 64  A   A N3    1 
ATOM 1049 C C4    . A   A 1 64  ? 176.514 159.905 197.413 1.00 99.19  ? 64  A   A C4    1 
ATOM 1050 P P     . C   A 1 65  ? 175.609 163.194 202.754 1.00 125.35 ? 65  C   A P     1 
ATOM 1051 O OP1   . C   A 1 65  ? 176.721 162.223 202.612 1.00 122.99 ? 65  C   A OP1   1 
ATOM 1052 O OP2   . C   A 1 65  ? 174.496 162.911 203.691 1.00 123.88 ? 65  C   A OP2   1 
ATOM 1053 O "O5'" . C   A 1 65  ? 176.227 164.601 203.165 1.00 123.87 ? 65  C   A "O5'" 1 
ATOM 1054 C "C5'" . C   A 1 65  ? 175.393 165.744 203.311 1.00 121.67 ? 65  C   A "C5'" 1 
ATOM 1055 C "C4'" . C   A 1 65  ? 175.945 166.721 204.320 1.00 121.41 ? 65  C   A "C4'" 1 
ATOM 1056 O "O4'" . C   A 1 65  ? 176.185 166.032 205.577 1.00 129.59 ? 65  C   A "O4'" 1 
ATOM 1057 C "C3'" . C   A 1 65  ? 177.267 167.385 203.939 1.00 124.86 ? 65  C   A "C3'" 1 
ATOM 1058 O "O3'" . C   A 1 65  ? 177.281 168.717 204.442 1.00 125.91 ? 65  C   A "O3'" 1 
ATOM 1059 C "C2'" . C   A 1 65  ? 178.293 166.551 204.698 1.00 125.78 ? 65  C   A "C2'" 1 
ATOM 1060 O "O2'" . C   A 1 65  ? 179.505 167.220 204.972 1.00 119.24 ? 65  C   A "O2'" 1 
ATOM 1061 C "C1'" . C   A 1 65  ? 177.529 166.220 205.974 1.00 128.93 ? 65  C   A "C1'" 1 
ATOM 1062 N N1    . C   A 1 65  ? 177.988 164.997 206.648 1.00 130.65 ? 65  C   A N1    1 
ATOM 1063 C C2    . C   A 1 65  ? 178.396 165.081 207.980 1.00 130.27 ? 65  C   A C2    1 
ATOM 1064 O O2    . C   A 1 65  ? 178.354 166.181 208.552 1.00 128.62 ? 65  C   A O2    1 
ATOM 1065 N N3    . C   A 1 65  ? 178.821 163.964 208.613 1.00 133.26 ? 65  C   A N3    1 
ATOM 1066 C C4    . C   A 1 65  ? 178.849 162.800 207.962 1.00 130.24 ? 65  C   A C4    1 
ATOM 1067 N N4    . C   A 1 65  ? 179.276 161.724 208.625 1.00 129.72 ? 65  C   A N4    1 
ATOM 1068 C C5    . C   A 1 65  ? 178.441 162.687 206.602 1.00 127.00 ? 65  C   A C5    1 
ATOM 1069 C C6    . C   A 1 65  ? 178.022 163.801 205.989 1.00 128.76 ? 65  C   A C6    1 
ATOM 1070 P P     . A   A 1 66  ? 176.854 169.937 203.492 1.00 110.56 ? 66  A   A P     1 
ATOM 1071 O OP1   . A   A 1 66  ? 177.597 169.791 202.216 1.00 97.52  ? 66  A   A OP1   1 
ATOM 1072 O OP2   . A   A 1 66  ? 176.974 171.191 204.275 1.00 99.30  ? 66  A   A OP2   1 
ATOM 1073 O "O5'" . A   A 1 66  ? 175.308 169.682 203.205 1.00 95.63  ? 66  A   A "O5'" 1 
ATOM 1074 C "C5'" . A   A 1 66  ? 174.453 170.753 202.835 1.00 97.99  ? 66  A   A "C5'" 1 
ATOM 1075 C "C4'" . A   A 1 66  ? 174.934 171.424 201.574 1.00 94.48  ? 66  A   A "C4'" 1 
ATOM 1076 O "O4'" . A   A 1 66  ? 174.834 170.508 200.456 1.00 90.67  ? 66  A   A "O4'" 1 
ATOM 1077 C "C3'" . A   A 1 66  ? 174.159 172.650 201.120 1.00 93.22  ? 66  A   A "C3'" 1 
ATOM 1078 O "O3'" . A   A 1 66  ? 174.555 173.817 201.823 1.00 95.34  ? 66  A   A "O3'" 1 
ATOM 1079 C "C2'" . A   A 1 66  ? 174.470 172.709 199.631 1.00 96.81  ? 66  A   A "C2'" 1 
ATOM 1080 O "O2'" . A   A 1 66  ? 175.739 173.304 199.423 1.00 113.92 ? 66  A   A "O2'" 1 
ATOM 1081 C "C1'" . A   A 1 66  ? 174.578 171.226 199.271 1.00 88.64  ? 66  A   A "C1'" 1 
ATOM 1082 N N9    . A   A 1 66  ? 173.359 170.697 198.633 1.00 87.15  ? 66  A   A N9    1 
ATOM 1083 C C8    . A   A 1 66  ? 172.073 170.694 199.103 1.00 91.15  ? 66  A   A C8    1 
ATOM 1084 N N7    . A   A 1 66  ? 171.215 170.134 198.285 1.00 95.62  ? 66  A   A N7    1 
ATOM 1085 C C5    . A   A 1 66  ? 171.991 169.740 197.207 1.00 87.77  ? 66  A   A C5    1 
ATOM 1086 C C6    . A   A 1 66  ? 171.681 169.090 196.004 1.00 85.14  ? 66  A   A C6    1 
ATOM 1087 N N6    . A   A 1 66  ? 170.449 168.703 195.672 1.00 91.13  ? 66  A   A N6    1 
ATOM 1088 N N1    . A   A 1 66  ? 172.687 168.846 195.141 1.00 86.62  ? 66  A   A N1    1 
ATOM 1089 C C2    . A   A 1 66  ? 173.920 169.237 195.474 1.00 92.54  ? 66  A   A C2    1 
ATOM 1090 N N3    . A   A 1 66  ? 174.337 169.854 196.574 1.00 90.72  ? 66  A   A N3    1 
ATOM 1091 C C4    . A   A 1 66  ? 173.312 170.077 197.410 1.00 89.34  ? 66  A   A C4    1 
ATOM 1092 P P     . U   A 1 67  ? 173.998 175.271 201.421 1.00 86.48  ? 67  U   A P     1 
ATOM 1093 O OP1   . U   A 1 67  ? 174.603 175.727 200.151 1.00 95.28  ? 67  U   A OP1   1 
ATOM 1094 O OP2   . U   A 1 67  ? 174.135 176.130 202.616 1.00 79.64  ? 67  U   A OP2   1 
ATOM 1095 O "O5'" . U   A 1 67  ? 172.443 175.051 201.196 1.00 60.16  ? 67  U   A "O5'" 1 
ATOM 1096 C "C5'" . U   A 1 67  ? 171.586 174.830 202.306 1.00 78.37  ? 67  U   A "C5'" 1 
ATOM 1097 C "C4'" . U   A 1 67  ? 170.322 175.644 202.215 1.00 80.75  ? 67  U   A "C4'" 1 
ATOM 1098 O "O4'" . U   A 1 67  ? 170.612 177.034 202.524 1.00 79.18  ? 67  U   A "O4'" 1 
ATOM 1099 C "C3'" . U   A 1 67  ? 169.629 175.639 200.853 1.00 70.48  ? 67  U   A "C3'" 1 
ATOM 1100 O "O3'" . U   A 1 67  ? 168.218 175.594 201.035 1.00 79.41  ? 67  U   A "O3'" 1 
ATOM 1101 C "C2'" . U   A 1 67  ? 170.010 176.993 200.267 1.00 69.93  ? 67  U   A "C2'" 1 
ATOM 1102 O "O2'" . U   A 1 67  ? 169.081 177.504 199.337 1.00 90.45  ? 67  U   A "O2'" 1 
ATOM 1103 C "C1'" . U   A 1 67  ? 170.079 177.861 201.514 1.00 68.64  ? 67  U   A "C1'" 1 
ATOM 1104 N N1    . U   A 1 67  ? 170.939 179.038 201.361 1.00 72.16  ? 67  U   A N1    1 
ATOM 1105 C C2    . U   A 1 67  ? 170.326 180.268 201.350 1.00 73.91  ? 67  U   A C2    1 
ATOM 1106 O O2    . U   A 1 67  ? 169.126 180.399 201.476 1.00 84.30  ? 67  U   A O2    1 
ATOM 1107 N N3    . U   A 1 67  ? 171.165 181.335 201.193 1.00 55.06  ? 67  U   A N3    1 
ATOM 1108 C C4    . U   A 1 67  ? 172.529 181.286 201.038 1.00 70.09  ? 67  U   A C4    1 
ATOM 1109 O O4    . U   A 1 67  ? 173.162 182.332 200.909 1.00 85.13  ? 67  U   A O4    1 
ATOM 1110 C C5    . U   A 1 67  ? 173.090 179.976 201.061 1.00 70.42  ? 67  U   A C5    1 
ATOM 1111 C C6    . U   A 1 67  ? 172.295 178.917 201.211 1.00 70.99  ? 67  U   A C6    1 
ATOM 1112 P P     . C   A 1 68  ? 167.290 174.924 199.913 1.00 88.92  ? 68  C   A P     1 
ATOM 1113 O OP1   . C   A 1 68  ? 167.448 173.453 199.996 1.00 73.77  ? 68  C   A OP1   1 
ATOM 1114 O OP2   . C   A 1 68  ? 167.533 175.624 198.630 1.00 82.98  ? 68  C   A OP2   1 
ATOM 1115 O "O5'" . C   A 1 68  ? 165.817 175.286 200.377 1.00 53.88  ? 68  C   A "O5'" 1 
ATOM 1116 C "C5'" . C   A 1 68  ? 165.158 174.523 201.377 1.00 58.23  ? 68  C   A "C5'" 1 
ATOM 1117 C "C4'" . C   A 1 68  ? 163.785 175.068 201.662 1.00 51.72  ? 68  C   A "C4'" 1 
ATOM 1118 O "O4'" . C   A 1 68  ? 163.916 176.336 202.357 1.00 61.75  ? 68  C   A "O4'" 1 
ATOM 1119 C "C3'" . C   A 1 68  ? 162.945 175.350 200.425 1.00 55.14  ? 68  C   A "C3'" 1 
ATOM 1120 O "O3'" . C   A 1 68  ? 161.568 175.141 200.729 1.00 60.08  ? 68  C   A "O3'" 1 
ATOM 1121 C "C2'" . C   A 1 68  ? 163.197 176.832 200.188 1.00 65.89  ? 68  C   A "C2'" 1 
ATOM 1122 O "O2'" . C   A 1 68  ? 162.195 177.484 199.444 1.00 80.58  ? 68  C   A "O2'" 1 
ATOM 1123 C "C1'" . C   A 1 68  ? 163.288 177.357 201.613 1.00 55.01  ? 68  C   A "C1'" 1 
ATOM 1124 N N1    . C   A 1 68  ? 164.102 178.569 201.750 1.00 57.44  ? 68  C   A N1    1 
ATOM 1125 C C2    . C   A 1 68  ? 163.491 179.765 202.116 1.00 63.90  ? 68  C   A C2    1 
ATOM 1126 O O2    . C   A 1 68  ? 162.273 179.772 202.309 1.00 65.65  ? 68  C   A O2    1 
ATOM 1127 N N3    . C   A 1 68  ? 164.230 180.884 202.249 1.00 63.32  ? 68  C   A N3    1 
ATOM 1128 C C4    . C   A 1 68  ? 165.538 180.825 202.032 1.00 66.42  ? 68  C   A C4    1 
ATOM 1129 N N4    . C   A 1 68  ? 166.240 181.947 202.175 1.00 71.36  ? 68  C   A N4    1 
ATOM 1130 C C5    . C   A 1 68  ? 166.192 179.617 201.659 1.00 59.45  ? 68  C   A C5    1 
ATOM 1131 C C6    . C   A 1 68  ? 165.444 178.518 201.531 1.00 60.17  ? 68  C   A C6    1 
ATOM 1132 P P     . A   A 1 69  ? 160.802 173.847 200.167 1.00 80.34  ? 69  A   A P     1 
ATOM 1133 O OP1   . A   A 1 69  ? 161.767 173.007 199.419 1.00 81.96  ? 69  A   A OP1   1 
ATOM 1134 O OP2   . A   A 1 69  ? 159.551 174.304 199.520 1.00 60.02  ? 69  A   A OP2   1 
ATOM 1135 O "O5'" . A   A 1 69  ? 160.395 173.052 201.480 1.00 71.74  ? 69  A   A "O5'" 1 
ATOM 1136 C "C5'" . A   A 1 69  ? 160.093 173.755 202.677 1.00 69.01  ? 69  A   A "C5'" 1 
ATOM 1137 C "C4'" . A   A 1 69  ? 159.684 172.819 203.780 1.00 40.90  ? 69  A   A "C4'" 1 
ATOM 1138 O "O4'" . A   A 1 69  ? 159.622 173.559 205.028 1.00 56.75  ? 69  A   A "O4'" 1 
ATOM 1139 C "C3'" . A   A 1 69  ? 158.314 172.179 203.601 1.00 57.94  ? 69  A   A "C3'" 1 
ATOM 1140 O "O3'" . A   A 1 69  ? 158.333 170.883 204.196 1.00 72.28  ? 69  A   A "O3'" 1 
ATOM 1141 C "C2'" . A   A 1 69  ? 157.418 173.098 204.418 1.00 66.60  ? 69  A   A "C2'" 1 
ATOM 1142 O "O2'" . A   A 1 69  ? 156.206 172.514 204.846 1.00 96.91  ? 69  A   A "O2'" 1 
ATOM 1143 C "C1'" . A   A 1 69  ? 158.334 173.424 205.587 1.00 65.38  ? 69  A   A "C1'" 1 
ATOM 1144 N N9    . A   A 1 69  ? 158.000 174.645 206.324 1.00 70.44  ? 69  A   A N9    1 
ATOM 1145 C C8    . A   A 1 69  ? 157.481 174.721 207.590 1.00 69.87  ? 69  A   A C8    1 
ATOM 1146 N N7    . A   A 1 69  ? 157.275 175.938 208.018 1.00 66.87  ? 69  A   A N7    1 
ATOM 1147 C C5    . A   A 1 69  ? 157.691 176.719 206.958 1.00 64.83  ? 69  A   A C5    1 
ATOM 1148 C C6    . A   A 1 69  ? 157.728 178.105 206.789 1.00 63.66  ? 69  A   A C6    1 
ATOM 1149 N N6    . A   A 1 69  ? 157.326 178.974 207.716 1.00 62.57  ? 69  A   A N6    1 
ATOM 1150 N N1    . A   A 1 69  ? 158.199 178.570 205.616 1.00 62.13  ? 69  A   A N1    1 
ATOM 1151 C C2    . A   A 1 69  ? 158.599 177.685 204.696 1.00 61.96  ? 69  A   A C2    1 
ATOM 1152 N N3    . A   A 1 69  ? 158.613 176.359 204.733 1.00 53.41  ? 69  A   A N3    1 
ATOM 1153 C C4    . A   A 1 69  ? 158.139 175.938 205.909 1.00 59.03  ? 69  A   A C4    1 
ATOM 1154 P P     . A   A 1 70  ? 157.311 169.746 203.708 1.00 86.65  ? 70  A   A P     1 
ATOM 1155 O OP1   . A   A 1 70  ? 157.190 169.828 202.234 1.00 78.60  ? 70  A   A OP1   1 
ATOM 1156 O OP2   . A   A 1 70  ? 156.099 169.823 204.555 1.00 88.18  ? 70  A   A OP2   1 
ATOM 1157 O "O5'" . A   A 1 70  ? 158.057 168.387 204.052 1.00 67.36  ? 70  A   A "O5'" 1 
ATOM 1158 C "C5'" . A   A 1 70  ? 159.132 168.365 204.979 1.00 67.89  ? 70  A   A "C5'" 1 
ATOM 1159 C "C4'" . A   A 1 70  ? 160.332 167.661 204.405 1.00 61.20  ? 70  A   A "C4'" 1 
ATOM 1160 O "O4'" . A   A 1 70  ? 159.902 166.376 203.880 1.00 51.22  ? 70  A   A "O4'" 1 
ATOM 1161 C "C3'" . A   A 1 70  ? 161.009 168.383 203.247 1.00 67.65  ? 70  A   A "C3'" 1 
ATOM 1162 O "O3'" . A   A 1 70  ? 162.404 168.067 203.250 1.00 81.87  ? 70  A   A "O3'" 1 
ATOM 1163 C "C2'" . A   A 1 70  ? 160.325 167.761 202.038 1.00 81.79  ? 70  A   A "C2'" 1 
ATOM 1164 O "O2'" . A   A 1 70  ? 161.033 167.855 200.822 1.00 101.66 ? 70  A   A "O2'" 1 
ATOM 1165 C "C1'" . A   A 1 70  ? 160.152 166.317 202.491 1.00 61.42  ? 70  A   A "C1'" 1 
ATOM 1166 N N9    . A   A 1 70  ? 159.013 165.656 201.855 1.00 74.77  ? 70  A   A N9    1 
ATOM 1167 C C8    . A   A 1 70  ? 157.765 166.186 201.676 1.00 77.41  ? 70  A   A C8    1 
ATOM 1168 N N7    . A   A 1 70  ? 156.931 165.386 201.066 1.00 79.06  ? 70  A   A N7    1 
ATOM 1169 C C5    . A   A 1 70  ? 157.686 164.253 200.824 1.00 72.39  ? 70  A   A C5    1 
ATOM 1170 C C6    . A   A 1 70  ? 157.374 163.039 200.205 1.00 71.05  ? 70  A   A C6    1 
ATOM 1171 N N6    . A   A 1 70  ? 156.173 162.765 199.703 1.00 83.09  ? 70  A   A N6    1 
ATOM 1172 N N1    . A   A 1 70  ? 158.338 162.108 200.117 1.00 63.60  ? 70  A   A N1    1 
ATOM 1173 C C2    . A   A 1 70  ? 159.532 162.400 200.628 1.00 72.83  ? 70  A   A C2    1 
ATOM 1174 N N3    . A   A 1 70  ? 159.957 163.503 201.234 1.00 82.03  ? 70  A   A N3    1 
ATOM 1175 C C4    . A   A 1 70  ? 158.969 164.403 201.302 1.00 76.55  ? 70  A   A C4    1 
ATOM 1176 P P     . G   A 1 71  ? 163.392 168.626 202.112 1.00 82.79  ? 71  G   A P     1 
ATOM 1177 O OP1   . G   A 1 71  ? 164.743 168.796 202.693 1.00 80.81  ? 71  G   A OP1   1 
ATOM 1178 O OP2   . G   A 1 71  ? 162.735 169.780 201.453 1.00 62.91  ? 71  G   A OP2   1 
ATOM 1179 O "O5'" . G   A 1 71  ? 163.438 167.424 201.071 1.00 79.30  ? 71  G   A "O5'" 1 
ATOM 1180 C "C5'" . G   A 1 71  ? 164.209 167.488 199.878 1.00 74.18  ? 71  G   A "C5'" 1 
ATOM 1181 C "C4'" . G   A 1 71  ? 164.502 166.104 199.357 1.00 72.40  ? 71  G   A "C4'" 1 
ATOM 1182 O "O4'" . G   A 1 71  ? 163.262 165.349 199.285 1.00 71.07  ? 71  G   A "O4'" 1 
ATOM 1183 C "C3'" . G   A 1 71  ? 165.123 166.036 197.964 1.00 73.99  ? 71  G   A "C3'" 1 
ATOM 1184 O "O3'" . G   A 1 71  ? 165.997 164.912 197.900 1.00 79.06  ? 71  G   A "O3'" 1 
ATOM 1185 C "C2'" . G   A 1 71  ? 163.915 165.766 197.080 1.00 71.58  ? 71  G   A "C2'" 1 
ATOM 1186 O "O2'" . G   A 1 71  ? 164.221 165.152 195.846 1.00 82.82  ? 71  G   A "O2'" 1 
ATOM 1187 C "C1'" . G   A 1 71  ? 163.094 164.849 197.976 1.00 67.79  ? 71  G   A "C1'" 1 
ATOM 1188 N N9    . G   A 1 71  ? 161.665 164.806 197.655 1.00 72.24  ? 71  G   A N9    1 
ATOM 1189 C C8    . G   A 1 71  ? 161.026 163.730 197.100 1.00 77.10  ? 71  G   A C8    1 
ATOM 1190 N N7    . G   A 1 71  ? 159.760 163.934 196.896 1.00 82.75  ? 71  G   A N7    1 
ATOM 1191 C C5    . G   A 1 71  ? 159.545 165.227 197.338 1.00 75.85  ? 71  G   A C5    1 
ATOM 1192 C C6    . G   A 1 71  ? 158.352 165.988 197.361 1.00 82.60  ? 71  G   A C6    1 
ATOM 1193 O O6    . G   A 1 71  ? 157.219 165.667 196.990 1.00 92.65  ? 71  G   A O6    1 
ATOM 1194 N N1    . G   A 1 71  ? 158.560 167.249 197.886 1.00 68.69  ? 71  G   A N1    1 
ATOM 1195 C C2    . G   A 1 71  ? 159.765 167.714 198.323 1.00 70.90  ? 71  G   A C2    1 
ATOM 1196 N N2    . G   A 1 71  ? 159.760 168.963 198.801 1.00 76.06  ? 71  G   A N2    1 
ATOM 1197 N N3    . G   A 1 71  ? 160.889 167.017 198.313 1.00 77.18  ? 71  G   A N3    1 
ATOM 1198 C C4    . G   A 1 71  ? 160.710 165.785 197.806 1.00 72.03  ? 71  G   A C4    1 
ATOM 1199 P P     . A   A 1 72  ? 167.565 165.087 198.185 1.00 105.29 ? 72  A   A P     1 
ATOM 1200 O OP1   . A   A 1 72  ? 167.917 164.267 199.367 1.00 93.94  ? 72  A   A OP1   1 
ATOM 1201 O OP2   . A   A 1 72  ? 167.861 166.540 198.176 1.00 101.26 ? 72  A   A OP2   1 
ATOM 1202 O "O5'" . A   A 1 72  ? 168.266 164.427 196.918 1.00 93.13  ? 72  A   A "O5'" 1 
ATOM 1203 C "C5'" . A   A 1 72  ? 167.966 164.869 195.600 1.00 87.78  ? 72  A   A "C5'" 1 
ATOM 1204 C "C4'" . A   A 1 72  ? 169.142 164.704 194.669 1.00 85.78  ? 72  A   A "C4'" 1 
ATOM 1205 O "O4'" . A   A 1 72  ? 170.183 165.645 195.040 1.00 97.56  ? 72  A   A "O4'" 1 
ATOM 1206 C "C3'" . A   A 1 72  ? 169.795 163.324 194.674 1.00 86.10  ? 72  A   A "C3'" 1 
ATOM 1207 O "O3'" . A   A 1 72  ? 170.310 163.039 193.373 1.00 98.79  ? 72  A   A "O3'" 1 
ATOM 1208 C "C2'" . A   A 1 72  ? 170.965 163.518 195.633 1.00 88.54  ? 72  A   A "C2'" 1 
ATOM 1209 O "O2'" . A   A 1 72  ? 172.030 162.610 195.451 1.00 87.85  ? 72  A   A "O2'" 1 
ATOM 1210 C "C1'" . A   A 1 72  ? 171.381 164.946 195.306 1.00 95.85  ? 72  A   A "C1'" 1 
ATOM 1211 N N9    . A   A 1 72  ? 172.086 165.644 196.380 1.00 94.84  ? 72  A   A N9    1 
ATOM 1212 C C8    . A   A 1 72  ? 171.586 166.101 197.571 1.00 95.81  ? 72  A   A C8    1 
ATOM 1213 N N7    . A   A 1 72  ? 172.473 166.710 198.317 1.00 96.02  ? 72  A   A N7    1 
ATOM 1214 C C5    . A   A 1 72  ? 173.630 166.659 197.559 1.00 92.49  ? 72  A   A C5    1 
ATOM 1215 C C6    . A   A 1 72  ? 174.930 167.127 197.789 1.00 91.80  ? 72  A   A C6    1 
ATOM 1216 N N6    . A   A 1 72  ? 175.299 167.772 198.897 1.00 87.33  ? 72  A   A N6    1 
ATOM 1217 N N1    . A   A 1 72  ? 175.848 166.909 196.823 1.00 92.08  ? 72  A   A N1    1 
ATOM 1218 C C2    . A   A 1 72  ? 175.476 166.262 195.711 1.00 90.07  ? 72  A   A C2    1 
ATOM 1219 N N3    . A   A 1 72  ? 174.287 165.775 195.383 1.00 85.91  ? 72  A   A N3    1 
ATOM 1220 C C4    . A   A 1 72  ? 173.402 166.013 196.361 1.00 89.69  ? 72  A   A C4    1 
ATOM 1221 P P     . G   A 1 73  ? 169.342 162.610 192.162 1.00 111.02 ? 73  G   A P     1 
ATOM 1222 O OP1   . G   A 1 73  ? 167.933 162.928 192.492 1.00 99.47  ? 73  G   A OP1   1 
ATOM 1223 O OP2   . G   A 1 73  ? 169.689 161.220 191.788 1.00 105.34 ? 73  G   A OP2   1 
ATOM 1224 O "O5'" . G   A 1 73  ? 169.787 163.568 190.968 1.00 105.86 ? 73  G   A "O5'" 1 
ATOM 1225 C "C5'" . G   A 1 73  ? 169.293 164.898 190.877 1.00 101.71 ? 73  G   A "C5'" 1 
ATOM 1226 C "C4'" . G   A 1 73  ? 170.400 165.918 190.988 1.00 95.31  ? 73  G   A "C4'" 1 
ATOM 1227 O "O4'" . G   A 1 73  ? 171.340 165.505 192.011 1.00 101.68 ? 73  G   A "O4'" 1 
ATOM 1228 C "C3'" . G   A 1 73  ? 171.265 166.114 189.755 1.00 97.45  ? 73  G   A "C3'" 1 
ATOM 1229 O "O3'" . G   A 1 73  ? 170.673 166.978 188.803 1.00 103.67 ? 73  G   A "O3'" 1 
ATOM 1230 C "C2'" . G   A 1 73  ? 172.556 166.663 190.343 1.00 99.84  ? 73  G   A "C2'" 1 
ATOM 1231 O "O2'" . G   A 1 73  ? 172.411 168.038 190.664 1.00 105.89 ? 73  G   A "O2'" 1 
ATOM 1232 C "C1'" . G   A 1 73  ? 172.648 165.883 191.646 1.00 92.89  ? 73  G   A "C1'" 1 
ATOM 1233 N N9    . G   A 1 73  ? 173.460 164.664 191.515 1.00 93.28  ? 73  G   A N9    1 
ATOM 1234 C C8    . G   A 1 73  ? 172.981 163.383 191.464 1.00 97.57  ? 73  G   A C8    1 
ATOM 1235 N N7    . G   A 1 73  ? 173.922 162.492 191.369 1.00 97.56  ? 73  G   A N7    1 
ATOM 1236 C C5    . G   A 1 73  ? 175.091 163.233 191.357 1.00 100.48 ? 73  G   A C5    1 
ATOM 1237 C C6    . G   A 1 73  ? 176.435 162.804 191.269 1.00 104.55 ? 73  G   A C6    1 
ATOM 1238 O O6    . G   A 1 73  ? 176.856 161.647 191.182 1.00 104.70 ? 73  G   A O6    1 
ATOM 1239 N N1    . G   A 1 73  ? 177.317 163.875 191.296 1.00 103.59 ? 73  G   A N1    1 
ATOM 1240 C C2    . G   A 1 73  ? 176.955 165.194 191.393 1.00 97.94  ? 73  G   A C2    1 
ATOM 1241 N N2    . G   A 1 73  ? 177.947 166.095 191.401 1.00 94.88  ? 73  G   A N2    1 
ATOM 1242 N N3    . G   A 1 73  ? 175.700 165.606 191.476 1.00 96.87  ? 73  G   A N3    1 
ATOM 1243 C C4    . G   A 1 73  ? 174.827 164.578 191.455 1.00 97.08  ? 73  G   A C4    1 
ATOM 1244 P P     . A   A 1 74  ? 171.049 166.850 187.247 1.00 104.55 ? 74  A   A P     1 
ATOM 1245 O OP1   . A   A 1 74  ? 170.349 167.949 186.540 1.00 103.34 ? 74  A   A OP1   1 
ATOM 1246 O OP2   . A   A 1 74  ? 170.844 165.442 186.828 1.00 101.56 ? 74  A   A OP2   1 
ATOM 1247 O "O5'" . A   A 1 74  ? 172.611 167.156 187.192 1.00 101.15 ? 74  A   A "O5'" 1 
ATOM 1248 C "C5'" . A   A 1 74  ? 173.099 168.471 187.401 1.00 96.40  ? 74  A   A "C5'" 1 
ATOM 1249 C "C4'" . A   A 1 74  ? 174.606 168.519 187.396 1.00 100.24 ? 74  A   A "C4'" 1 
ATOM 1250 O "O4'" . A   A 1 74  ? 175.148 167.708 188.468 1.00 96.65  ? 74  A   A "O4'" 1 
ATOM 1251 C "C3'" . A   A 1 74  ? 175.305 167.986 186.160 1.00 104.98 ? 74  A   A "C3'" 1 
ATOM 1252 O "O3'" . A   A 1 74  ? 175.265 168.895 185.075 1.00 106.69 ? 74  A   A "O3'" 1 
ATOM 1253 C "C2'" . A   A 1 74  ? 176.709 167.716 186.681 1.00 104.14 ? 74  A   A "C2'" 1 
ATOM 1254 O "O2'" . A   A 1 74  ? 177.446 168.924 186.788 1.00 109.23 ? 74  A   A "O2'" 1 
ATOM 1255 C "C1'" . A   A 1 74  ? 176.417 167.214 188.091 1.00 95.29  ? 74  A   A "C1'" 1 
ATOM 1256 N N9    . A   A 1 74  ? 176.409 165.745 188.166 1.00 93.27  ? 74  A   A N9    1 
ATOM 1257 C C8    . A   A 1 74  ? 175.328 164.916 188.263 1.00 98.72  ? 74  A   A C8    1 
ATOM 1258 N N7    . A   A 1 74  ? 175.648 163.648 188.321 1.00 104.29 ? 74  A   A N7    1 
ATOM 1259 C C5    . A   A 1 74  ? 177.031 163.646 188.254 1.00 102.24 ? 74  A   A C5    1 
ATOM 1260 C C6    . A   A 1 74  ? 177.974 162.608 188.274 1.00 102.00 ? 74  A   A C6    1 
ATOM 1261 N N6    . A   A 1 74  ? 177.649 161.319 188.363 1.00 100.60 ? 74  A   A N6    1 
ATOM 1262 N N1    . A   A 1 74  ? 179.278 162.939 188.193 1.00 100.48 ? 74  A   A N1    1 
ATOM 1263 C C2    . A   A 1 74  ? 179.599 164.234 188.104 1.00 96.84  ? 74  A   A C2    1 
ATOM 1264 N N3    . A   A 1 74  ? 178.801 165.299 188.081 1.00 96.15  ? 74  A   A N3    1 
ATOM 1265 C C4    . A   A 1 74  ? 177.514 164.932 188.162 1.00 97.24  ? 74  A   A C4    1 
ATOM 1266 P P     . U   A 1 75  ? 175.767 168.462 183.614 1.00 108.72 ? 75  U   A P     1 
ATOM 1267 O OP1   . U   A 1 75  ? 175.417 169.558 182.680 1.00 108.12 ? 75  U   A OP1   1 
ATOM 1268 O OP2   . U   A 1 75  ? 175.340 167.065 183.358 1.00 110.10 ? 75  U   A OP2   1 
ATOM 1269 O "O5'" . U   A 1 75  ? 177.348 168.385 183.745 1.00 105.95 ? 75  U   A "O5'" 1 
ATOM 1270 C "C5'" . U   A 1 75  ? 178.167 169.540 183.752 1.00 104.31 ? 75  U   A "C5'" 1 
ATOM 1271 C "C4'" . U   A 1 75  ? 179.604 169.127 183.609 1.00 105.44 ? 75  U   A "C4'" 1 
ATOM 1272 O "O4'" . U   A 1 75  ? 179.952 168.267 184.725 1.00 103.82 ? 75  U   A "O4'" 1 
ATOM 1273 C "C3'" . U   A 1 75  ? 179.895 168.281 182.379 1.00 110.62 ? 75  U   A "C3'" 1 
ATOM 1274 O "O3'" . U   A 1 75  ? 180.140 169.058 181.220 1.00 111.69 ? 75  U   A "O3'" 1 
ATOM 1275 C "C2'" . U   A 1 75  ? 181.082 167.435 182.815 1.00 112.04 ? 75  U   A "C2'" 1 
ATOM 1276 O "O2'" . U   A 1 75  ? 182.285 168.184 182.736 1.00 113.80 ? 75  U   A "O2'" 1 
ATOM 1277 C "C1'" . U   A 1 75  ? 180.759 167.196 184.286 1.00 108.44 ? 75  U   A "C1'" 1 
ATOM 1278 N N1    . U   A 1 75  ? 180.018 165.933 184.515 1.00 110.73 ? 75  U   A N1    1 
ATOM 1279 C C2    . U   A 1 75  ? 180.717 164.750 184.656 1.00 114.71 ? 75  U   A C2    1 
ATOM 1280 O O2    . U   A 1 75  ? 181.931 164.689 184.584 1.00 115.45 ? 75  U   A O2    1 
ATOM 1281 N N3    . U   A 1 75  ? 179.935 163.639 184.882 1.00 112.12 ? 75  U   A N3    1 
ATOM 1282 C C4    . U   A 1 75  ? 178.560 163.590 184.980 1.00 107.80 ? 75  U   A C4    1 
ATOM 1283 O O4    . U   A 1 75  ? 177.984 162.524 185.188 1.00 107.07 ? 75  U   A O4    1 
ATOM 1284 C C5    . U   A 1 75  ? 177.913 164.851 184.829 1.00 105.77 ? 75  U   A C5    1 
ATOM 1285 C C6    . U   A 1 75  ? 178.652 165.936 184.611 1.00 106.36 ? 75  U   A C6    1 
ATOM 1286 P P     . U   A 1 76  ? 179.741 168.494 179.770 1.00 133.49 ? 76  U   A P     1 
ATOM 1287 O OP1   . U   A 1 76  ? 180.002 169.564 178.779 1.00 129.07 ? 76  U   A OP1   1 
ATOM 1288 O OP2   . U   A 1 76  ? 178.389 167.890 179.856 1.00 132.33 ? 76  U   A OP2   1 
ATOM 1289 O "O5'" . U   A 1 76  ? 180.791 167.328 179.514 1.00 132.08 ? 76  U   A "O5'" 1 
ATOM 1290 C "C5'" . U   A 1 76  ? 182.173 167.616 179.387 1.00 130.62 ? 76  U   A "C5'" 1 
ATOM 1291 C "C4'" . U   A 1 76  ? 183.011 166.372 179.525 1.00 129.77 ? 76  U   A "C4'" 1 
ATOM 1292 O "O4'" . U   A 1 76  ? 182.724 165.730 180.794 1.00 129.60 ? 76  U   A "O4'" 1 
ATOM 1293 C "C3'" . U   A 1 76  ? 182.758 165.281 178.499 1.00 131.21 ? 76  U   A "C3'" 1 
ATOM 1294 O "O3'" . U   A 1 76  ? 183.412 165.511 177.265 1.00 131.12 ? 76  U   A "O3'" 1 
ATOM 1295 C "C2'" . U   A 1 76  ? 183.243 164.035 179.221 1.00 130.64 ? 76  U   A "C2'" 1 
ATOM 1296 O "O2'" . U   A 1 76  ? 184.661 163.965 179.200 1.00 128.76 ? 76  U   A "O2'" 1 
ATOM 1297 C "C1'" . U   A 1 76  ? 182.796 164.327 180.650 1.00 130.11 ? 76  U   A "C1'" 1 
ATOM 1298 N N1    . U   A 1 76  ? 181.462 163.753 180.937 1.00 129.01 ? 76  U   A N1    1 
ATOM 1299 C C2    . U   A 1 76  ? 181.398 162.404 181.225 1.00 129.77 ? 76  U   A C2    1 
ATOM 1300 O O2    . U   A 1 76  ? 182.381 161.686 181.253 1.00 131.33 ? 76  U   A O2    1 
ATOM 1301 N N3    . U   A 1 76  ? 180.140 161.921 181.481 1.00 130.08 ? 76  U   A N3    1 
ATOM 1302 C C4    . U   A 1 76  ? 178.964 162.642 181.476 1.00 129.55 ? 76  U   A C4    1 
ATOM 1303 O O4    . U   A 1 76  ? 177.900 162.075 181.727 1.00 130.70 ? 76  U   A O4    1 
ATOM 1304 C C5    . U   A 1 76  ? 179.112 164.030 181.168 1.00 126.48 ? 76  U   A C5    1 
ATOM 1305 C C6    . U   A 1 76  ? 180.325 164.526 180.915 1.00 127.00 ? 76  U   A C6    1 
ATOM 1306 P P     . U   A 1 77  ? 182.703 165.084 175.888 1.00 152.21 ? 77  U   A P     1 
ATOM 1307 O OP1   . U   A 1 77  ? 183.534 165.586 174.767 1.00 147.90 ? 77  U   A OP1   1 
ATOM 1308 O OP2   . U   A 1 77  ? 181.274 165.478 175.972 1.00 147.60 ? 77  U   A OP2   1 
ATOM 1309 O "O5'" . U   A 1 77  ? 182.780 163.493 175.890 1.00 150.01 ? 77  U   A "O5'" 1 
ATOM 1310 C "C5'" . U   A 1 77  ? 184.028 162.821 175.986 1.00 148.88 ? 77  U   A "C5'" 1 
ATOM 1311 C "C4'" . U   A 1 77  ? 183.853 161.400 176.457 1.00 147.86 ? 77  U   A "C4'" 1 
ATOM 1312 O "O4'" . U   A 1 77  ? 183.111 161.389 177.703 1.00 148.21 ? 77  U   A "O4'" 1 
ATOM 1313 C "C3'" . U   A 1 77  ? 183.053 160.495 175.535 1.00 147.77 ? 77  U   A "C3'" 1 
ATOM 1314 O "O3'" . U   A 1 77  ? 183.846 159.946 174.498 1.00 147.67 ? 77  U   A "O3'" 1 
ATOM 1315 C "C2'" . U   A 1 77  ? 182.491 159.448 176.488 1.00 147.82 ? 77  U   A "C2'" 1 
ATOM 1316 O "O2'" . U   A 1 77  ? 183.468 158.463 176.785 1.00 146.33 ? 77  U   A "O2'" 1 
ATOM 1317 C "C1'" . U   A 1 77  ? 182.244 160.279 177.745 1.00 147.55 ? 77  U   A "C1'" 1 
ATOM 1318 N N1    . U   A 1 77  ? 180.854 160.780 177.829 1.00 146.39 ? 77  U   A N1    1 
ATOM 1319 C C2    . U   A 1 77  ? 179.857 159.889 178.169 1.00 146.70 ? 77  U   A C2    1 
ATOM 1320 O O2    . U   A 1 77  ? 180.070 158.711 178.392 1.00 147.00 ? 77  U   A O2    1 
ATOM 1321 N N3    . U   A 1 77  ? 178.596 160.428 178.232 1.00 146.81 ? 77  U   A N3    1 
ATOM 1322 C C4    . U   A 1 77  ? 178.244 161.742 177.998 1.00 145.90 ? 77  U   A C4    1 
ATOM 1323 O O4    . U   A 1 77  ? 177.065 162.082 178.093 1.00 146.30 ? 77  U   A O4    1 
ATOM 1324 C C5    . U   A 1 77  ? 179.332 162.602 177.658 1.00 145.13 ? 77  U   A C5    1 
ATOM 1325 C C6    . U   A 1 77  ? 180.568 162.102 177.590 1.00 144.80 ? 77  U   A C6    1 
ATOM 1326 P P     . C   A 1 78  ? 183.167 159.492 173.118 1.00 158.21 ? 78  C   A P     1 
ATOM 1327 O OP1   . C   A 1 78  ? 184.220 158.892 172.262 1.00 160.16 ? 78  C   A OP1   1 
ATOM 1328 O OP2   . C   A 1 78  ? 182.353 160.625 172.609 1.00 156.78 ? 78  C   A OP2   1 
ATOM 1329 O "O5'" . C   A 1 78  ? 182.168 158.332 173.551 1.00 156.29 ? 78  C   A "O5'" 1 
ATOM 1330 C "C5'" . C   A 1 78  ? 182.633 157.013 173.822 1.00 154.71 ? 78  C   A "C5'" 1 
ATOM 1331 C "C4'" . C   A 1 78  ? 181.549 156.001 173.558 1.00 157.73 ? 78  C   A "C4'" 1 
ATOM 1332 O "O4'" . C   A 1 78  ? 180.476 156.216 174.523 1.00 156.10 ? 78  C   A "O4'" 1 
ATOM 1333 C "C3'" . C   A 1 78  ? 180.910 156.124 172.171 1.00 161.31 ? 78  C   A "C3'" 1 
ATOM 1334 O "O3'" . C   A 1 78  ? 180.535 154.862 171.600 1.00 163.56 ? 78  C   A "O3'" 1 
ATOM 1335 C "C2'" . C   A 1 78  ? 179.649 156.927 172.452 1.00 162.93 ? 78  C   A "C2'" 1 
ATOM 1336 O "O2'" . C   A 1 78  ? 178.619 156.747 171.505 1.00 159.45 ? 78  C   A "O2'" 1 
ATOM 1337 C "C1'" . C   A 1 78  ? 179.260 156.404 173.831 1.00 161.61 ? 78  C   A "C1'" 1 
ATOM 1338 N N1    . C   A 1 78  ? 178.368 157.311 174.562 1.00 159.18 ? 78  C   A N1    1 
ATOM 1339 C C2    . C   A 1 78  ? 177.167 156.773 175.013 1.00 158.61 ? 78  C   A C2    1 
ATOM 1340 O O2    . C   A 1 78  ? 176.980 155.562 174.829 1.00 158.97 ? 78  C   A O2    1 
ATOM 1341 N N3    . C   A 1 78  ? 176.273 157.564 175.639 1.00 159.24 ? 78  C   A N3    1 
ATOM 1342 C C4    . C   A 1 78  ? 176.547 158.858 175.801 1.00 158.79 ? 78  C   A C4    1 
ATOM 1343 N N4    . C   A 1 78  ? 175.640 159.610 176.428 1.00 159.73 ? 78  C   A N4    1 
ATOM 1344 C C5    . C   A 1 78  ? 177.759 159.441 175.328 1.00 157.44 ? 78  C   A C5    1 
ATOM 1345 C C6    . C   A 1 78  ? 178.633 158.642 174.707 1.00 158.07 ? 78  C   A C6    1 
ATOM 1346 P P     . G   A 1 79  ? 180.638 153.454 172.372 1.00 173.61 ? 79  G   A P     1 
ATOM 1347 O OP1   . G   A 1 79  ? 179.961 153.465 173.693 1.00 164.06 ? 79  G   A OP1   1 
ATOM 1348 O OP2   . G   A 1 79  ? 182.048 153.006 172.265 1.00 161.24 ? 79  G   A OP2   1 
ATOM 1349 O "O5'" . G   A 1 79  ? 179.731 152.499 171.471 1.00 164.58 ? 79  G   A "O5'" 1 
ATOM 1350 C "C5'" . G   A 1 79  ? 178.778 153.040 170.561 1.00 160.62 ? 79  G   A "C5'" 1 
ATOM 1351 C "C4'" . G   A 1 79  ? 177.377 152.557 170.861 1.00 161.61 ? 79  G   A "C4'" 1 
ATOM 1352 O "O4'" . G   A 1 79  ? 176.911 153.147 172.100 1.00 159.87 ? 79  G   A "O4'" 1 
ATOM 1353 C "C3'" . G   A 1 79  ? 176.293 152.929 169.857 1.00 161.69 ? 79  G   A "C3'" 1 
ATOM 1354 O "O3'" . G   A 1 79  ? 176.271 152.094 168.713 1.00 162.38 ? 79  G   A "O3'" 1 
ATOM 1355 C "C2'" . G   A 1 79  ? 175.022 152.828 170.690 1.00 160.63 ? 79  G   A "C2'" 1 
ATOM 1356 O "O2'" . G   A 1 79  ? 174.616 151.475 170.823 1.00 159.43 ? 79  G   A "O2'" 1 
ATOM 1357 C "C1'" . G   A 1 79  ? 175.508 153.313 172.053 1.00 159.31 ? 79  G   A "C1'" 1 
ATOM 1358 N N9    . G   A 1 79  ? 175.162 154.722 172.316 1.00 159.38 ? 79  G   A N9    1 
ATOM 1359 C C8    . G   A 1 79  ? 175.952 155.838 172.245 1.00 158.50 ? 79  G   A C8    1 
ATOM 1360 N N7    . G   A 1 79  ? 175.321 156.936 172.574 1.00 158.05 ? 79  G   A N7    1 
ATOM 1361 C C5    . G   A 1 79  ? 174.031 156.519 172.868 1.00 158.75 ? 79  G   A C5    1 
ATOM 1362 C C6    . G   A 1 79  ? 172.881 157.248 173.274 1.00 158.41 ? 79  G   A C6    1 
ATOM 1363 O O6    . G   A 1 79  ? 172.746 158.460 173.473 1.00 157.03 ? 79  G   A O6    1 
ATOM 1364 N N1    . G   A 1 79  ? 171.789 156.409 173.458 1.00 160.50 ? 79  G   A N1    1 
ATOM 1365 C C2    . G   A 1 79  ? 171.799 155.050 173.274 1.00 161.17 ? 79  G   A C2    1 
ATOM 1366 N N2    . G   A 1 79  ? 170.647 154.406 173.493 1.00 162.76 ? 79  G   A N2    1 
ATOM 1367 N N3    . G   A 1 79  ? 172.857 154.362 172.896 1.00 160.82 ? 79  G   A N3    1 
ATOM 1368 C C4    . G   A 1 79  ? 173.926 155.155 172.715 1.00 159.86 ? 79  G   A C4    1 
ATOM 1369 P P     . G   A 1 80  ? 175.447 152.538 167.405 1.00 151.57 ? 80  G   A P     1 
ATOM 1370 O OP1   . G   A 1 80  ? 175.730 151.555 166.329 1.00 151.52 ? 80  G   A OP1   1 
ATOM 1371 O OP2   . G   A 1 80  ? 175.706 153.981 167.175 1.00 146.31 ? 80  G   A OP2   1 
ATOM 1372 O "O5'" . G   A 1 80  ? 173.914 152.386 167.819 1.00 149.53 ? 80  G   A "O5'" 1 
ATOM 1373 C "C5'" . G   A 1 80  ? 173.319 151.107 167.986 1.00 148.46 ? 80  G   A "C5'" 1 
ATOM 1374 C "C4'" . G   A 1 80  ? 171.878 151.219 168.424 1.00 148.50 ? 80  G   A "C4'" 1 
ATOM 1375 O "O4'" . G   A 1 80  ? 171.801 151.895 169.704 1.00 147.29 ? 80  G   A "O4'" 1 
ATOM 1376 C "C3'" . G   A 1 80  ? 170.971 152.036 167.517 1.00 148.96 ? 80  G   A "C3'" 1 
ATOM 1377 O "O3'" . G   A 1 80  ? 170.501 151.294 166.406 1.00 150.62 ? 80  G   A "O3'" 1 
ATOM 1378 C "C2'" . G   A 1 80  ? 169.862 152.481 168.461 1.00 148.92 ? 80  G   A "C2'" 1 
ATOM 1379 O "O2'" . G   A 1 80  ? 168.921 151.436 168.652 1.00 148.47 ? 80  G   A "O2'" 1 
ATOM 1380 C "C1'" . G   A 1 80  ? 170.631 152.683 169.766 1.00 147.69 ? 80  G   A "C1'" 1 
ATOM 1381 N N9    . G   A 1 80  ? 171.023 154.087 169.987 1.00 147.03 ? 80  G   A N9    1 
ATOM 1382 C C8    . G   A 1 80  ? 172.289 154.601 169.873 1.00 147.67 ? 80  G   A C8    1 
ATOM 1383 N N7    . G   A 1 80  ? 172.358 155.873 170.142 1.00 147.24 ? 80  G   A N7    1 
ATOM 1384 C C5    . G   A 1 80  ? 171.056 156.224 170.453 1.00 146.07 ? 80  G   A C5    1 
ATOM 1385 C C6    . G   A 1 80  ? 170.521 157.478 170.829 1.00 144.99 ? 80  G   A C6    1 
ATOM 1386 O O6    . G   A 1 80  ? 171.106 158.556 170.961 1.00 145.36 ? 80  G   A O6    1 
ATOM 1387 N N1    . G   A 1 80  ? 169.157 157.399 171.060 1.00 144.16 ? 80  G   A N1    1 
ATOM 1388 C C2    . G   A 1 80  ? 168.405 156.258 170.950 1.00 147.00 ? 80  G   A C2    1 
ATOM 1389 N N2    . G   A 1 80  ? 167.098 156.381 171.211 1.00 149.56 ? 80  G   A N2    1 
ATOM 1390 N N3    . G   A 1 80  ? 168.893 155.080 170.599 1.00 147.21 ? 80  G   A N3    1 
ATOM 1391 C C4    . G   A 1 80  ? 170.219 155.134 170.370 1.00 146.20 ? 80  G   A C4    1 
ATOM 1392 P P     . A   A 1 81  ? 170.115 152.041 165.038 1.00 154.35 ? 81  A   A P     1 
ATOM 1393 O OP1   . A   A 1 81  ? 169.845 151.003 164.012 1.00 148.34 ? 81  A   A OP1   1 
ATOM 1394 O OP2   . A   A 1 81  ? 171.137 153.085 164.775 1.00 148.31 ? 81  A   A OP2   1 
ATOM 1395 O "O5'" . A   A 1 81  ? 168.740 152.769 165.374 1.00 150.05 ? 81  A   A "O5'" 1 
ATOM 1396 C "C5'" . A   A 1 81  ? 167.574 152.018 165.679 1.00 147.89 ? 81  A   A "C5'" 1 
ATOM 1397 C "C4'" . A   A 1 81  ? 166.465 152.909 166.172 1.00 148.33 ? 81  A   A "C4'" 1 
ATOM 1398 O "O4'" . A   A 1 81  ? 166.847 153.505 167.438 1.00 145.81 ? 81  A   A "O4'" 1 
ATOM 1399 C "C3'" . A   A 1 81  ? 166.133 154.099 165.287 1.00 148.06 ? 81  A   A "C3'" 1 
ATOM 1400 O "O3'" . A   A 1 81  ? 165.287 153.765 164.201 1.00 143.85 ? 81  A   A "O3'" 1 
ATOM 1401 C "C2'" . A   A 1 81  ? 165.510 155.080 166.270 1.00 148.05 ? 81  A   A "C2'" 1 
ATOM 1402 O "O2'" . A   A 1 81  ? 164.166 154.722 166.552 1.00 148.38 ? 81  A   A "O2'" 1 
ATOM 1403 C "C1'" . A   A 1 81  ? 166.350 154.823 167.520 1.00 145.98 ? 81  A   A "C1'" 1 
ATOM 1404 N N9    . A   A 1 81  ? 167.497 155.744 167.607 1.00 145.20 ? 81  A   A N9    1 
ATOM 1405 C C8    . A   A 1 81  ? 168.811 155.470 167.332 1.00 145.25 ? 81  A   A C8    1 
ATOM 1406 N N7    . A   A 1 81  ? 169.611 156.492 167.499 1.00 143.21 ? 81  A   A N7    1 
ATOM 1407 C C5    . A   A 1 81  ? 168.762 157.508 167.906 1.00 143.29 ? 81  A   A C5    1 
ATOM 1408 C C6    . A   A 1 81  ? 168.995 158.847 168.243 1.00 142.88 ? 81  A   A C6    1 
ATOM 1409 N N6    . A   A 1 81  ? 170.201 159.413 168.221 1.00 142.94 ? 81  A   A N6    1 
ATOM 1410 N N1    . A   A 1 81  ? 167.936 159.595 168.609 1.00 144.07 ? 81  A   A N1    1 
ATOM 1411 C C2    . A   A 1 81  ? 166.725 159.028 168.631 1.00 144.68 ? 81  A   A C2    1 
ATOM 1412 N N3    . A   A 1 81  ? 166.379 157.779 168.336 1.00 144.19 ? 81  A   A N3    1 
ATOM 1413 C C4    . A   A 1 81  ? 167.457 157.064 167.976 1.00 144.52 ? 81  A   A C4    1 
ATOM 1414 N N     . MET B 2 1   ? 124.143 158.037 202.949 1.00 233.37 ? 1   MET B N     1 
ATOM 1415 C CA    . MET B 2 1   ? 124.174 156.661 202.467 1.00 233.69 ? 1   MET B CA    1 
ATOM 1416 C C     . MET B 2 1   ? 125.379 155.920 203.042 1.00 234.18 ? 1   MET B C     1 
ATOM 1417 O O     . MET B 2 1   ? 126.004 155.107 202.360 1.00 232.84 ? 1   MET B O     1 
ATOM 1418 C CB    . MET B 2 1   ? 124.207 156.629 200.937 1.00 231.63 ? 1   MET B CB    1 
ATOM 1419 C CG    . MET B 2 1   ? 122.974 157.227 200.276 1.00 230.80 ? 1   MET B CG    1 
ATOM 1420 S SD    . MET B 2 1   ? 121.521 156.174 200.426 1.00 228.99 ? 1   MET B SD    1 
ATOM 1421 C CE    . MET B 2 1   ? 120.273 157.201 199.652 1.00 229.47 ? 1   MET B CE    1 
ATOM 1422 N N     . ASP B 2 2   ? 125.698 156.209 204.301 1.00 266.44 ? 2   ASP B N     1 
ATOM 1423 C CA    . ASP B 2 2   ? 126.866 155.642 204.972 1.00 266.30 ? 2   ASP B CA    1 
ATOM 1424 C C     . ASP B 2 2   ? 126.493 155.170 206.375 1.00 267.34 ? 2   ASP B C     1 
ATOM 1425 O O     . ASP B 2 2   ? 127.175 155.463 207.358 1.00 267.49 ? 2   ASP B O     1 
ATOM 1426 C CB    . ASP B 2 2   ? 128.008 156.656 205.012 1.00 266.04 ? 2   ASP B CB    1 
ATOM 1427 C CG    . ASP B 2 2   ? 127.621 157.944 205.714 1.00 266.58 ? 2   ASP B CG    1 
ATOM 1428 O OD1   . ASP B 2 2   ? 126.416 158.145 205.975 1.00 266.87 ? 2   ASP B OD1   1 
ATOM 1429 O OD2   . ASP B 2 2   ? 128.523 158.755 206.008 1.00 267.59 ? 2   ASP B OD2   1 
ATOM 1430 N N     . VAL B 2 3   ? 125.391 154.422 206.479 1.00 271.02 ? 3   VAL B N     1 
ATOM 1431 C CA    . VAL B 2 3   ? 124.924 153.941 207.776 1.00 270.53 ? 3   VAL B CA    1 
ATOM 1432 C C     . VAL B 2 3   ? 125.927 153.003 208.429 1.00 270.14 ? 3   VAL B C     1 
ATOM 1433 O O     . VAL B 2 3   ? 125.913 152.836 209.653 1.00 270.34 ? 3   VAL B O     1 
ATOM 1434 C CB    . VAL B 2 3   ? 123.554 153.250 207.633 1.00 269.55 ? 3   VAL B CB    1 
ATOM 1435 C CG1   . VAL B 2 3   ? 122.487 154.261 207.255 1.00 269.29 ? 3   VAL B CG1   1 
ATOM 1436 C CG2   . VAL B 2 3   ? 123.629 152.137 206.603 1.00 269.82 ? 3   VAL B CG2   1 
ATOM 1437 N N     . PHE B 2 4   ? 126.801 152.381 207.637 1.00 261.13 ? 4   PHE B N     1 
ATOM 1438 C CA    . PHE B 2 4   ? 127.784 151.455 208.188 1.00 260.68 ? 4   PHE B CA    1 
ATOM 1439 C C     . PHE B 2 4   ? 128.770 152.153 209.113 1.00 261.34 ? 4   PHE B C     1 
ATOM 1440 O O     . PHE B 2 4   ? 129.286 151.530 210.047 1.00 261.52 ? 4   PHE B O     1 
ATOM 1441 C CB    . PHE B 2 4   ? 128.527 150.763 207.052 1.00 259.67 ? 4   PHE B CB    1 
ATOM 1442 C CG    . PHE B 2 4   ? 128.931 151.691 205.939 1.00 260.12 ? 4   PHE B CG    1 
ATOM 1443 C CD1   . PHE B 2 4   ? 128.178 151.764 204.778 1.00 259.97 ? 4   PHE B CD1   1 
ATOM 1444 C CD2   . PHE B 2 4   ? 130.066 152.478 206.044 1.00 260.51 ? 4   PHE B CD2   1 
ATOM 1445 C CE1   . PHE B 2 4   ? 128.541 152.612 203.750 1.00 259.25 ? 4   PHE B CE1   1 
ATOM 1446 C CE2   . PHE B 2 4   ? 130.435 153.327 205.018 1.00 260.46 ? 4   PHE B CE2   1 
ATOM 1447 C CZ    . PHE B 2 4   ? 129.671 153.393 203.869 1.00 259.60 ? 4   PHE B CZ    1 
ATOM 1448 N N     . GLN B 2 5   ? 129.042 153.436 208.872 1.00 277.08 ? 5   GLN B N     1 
ATOM 1449 C CA    . GLN B 2 5   ? 130.006 154.153 209.697 1.00 277.70 ? 5   GLN B CA    1 
ATOM 1450 C C     . GLN B 2 5   ? 129.556 154.221 211.150 1.00 278.43 ? 5   GLN B C     1 
ATOM 1451 O O     . GLN B 2 5   ? 130.372 154.027 212.059 1.00 278.85 ? 5   GLN B O     1 
ATOM 1452 C CB    . GLN B 2 5   ? 130.232 155.557 209.133 1.00 277.66 ? 5   GLN B CB    1 
ATOM 1453 C CG    . GLN B 2 5   ? 130.974 156.506 210.063 1.00 277.95 ? 5   GLN B CG    1 
ATOM 1454 C CD    . GLN B 2 5   ? 130.042 157.312 210.946 1.00 278.44 ? 5   GLN B CD    1 
ATOM 1455 O OE1   . GLN B 2 5   ? 128.857 157.456 210.648 1.00 278.84 ? 5   GLN B OE1   1 
ATOM 1456 N NE2   . GLN B 2 5   ? 130.573 157.837 212.044 1.00 278.50 ? 5   GLN B NE2   1 
ATOM 1457 N N     . GLU B 2 6   ? 128.270 154.490 211.388 1.00 279.73 ? 6   GLU B N     1 
ATOM 1458 C CA    . GLU B 2 6   ? 127.764 154.544 212.755 1.00 279.80 ? 6   GLU B CA    1 
ATOM 1459 C C     . GLU B 2 6   ? 127.932 153.199 213.450 1.00 279.65 ? 6   GLU B C     1 
ATOM 1460 O O     . GLU B 2 6   ? 128.393 153.131 214.595 1.00 280.23 ? 6   GLU B O     1 
ATOM 1461 C CB    . GLU B 2 6   ? 126.296 154.968 212.749 1.00 279.14 ? 6   GLU B CB    1 
ATOM 1462 C CG    . GLU B 2 6   ? 126.064 156.392 212.279 1.00 279.15 ? 6   GLU B CG    1 
ATOM 1463 C CD    . GLU B 2 6   ? 125.903 156.487 210.773 1.00 278.68 ? 6   GLU B CD    1 
ATOM 1464 O OE1   . GLU B 2 6   ? 126.460 155.626 210.061 1.00 278.52 ? 6   GLU B OE1   1 
ATOM 1465 O OE2   . GLU B 2 6   ? 125.222 157.420 210.301 1.00 278.72 ? 6   GLU B OE2   1 
ATOM 1466 N N     . GLY B 2 7   ? 127.575 152.114 212.762 1.00 272.86 ? 7   GLY B N     1 
ATOM 1467 C CA    . GLY B 2 7   ? 127.714 150.795 213.357 1.00 272.62 ? 7   GLY B CA    1 
ATOM 1468 C C     . GLY B 2 7   ? 129.155 150.441 213.659 1.00 272.14 ? 7   GLY B C     1 
ATOM 1469 O O     . GLY B 2 7   ? 129.458 149.877 214.712 1.00 272.04 ? 7   GLY B O     1 
ATOM 1470 N N     . LEU B 2 8   ? 130.065 150.772 212.741 1.00 257.49 ? 8   LEU B N     1 
ATOM 1471 C CA    . LEU B 2 8   ? 131.478 150.491 212.966 1.00 256.81 ? 8   LEU B CA    1 
ATOM 1472 C C     . LEU B 2 8   ? 132.015 151.285 214.148 1.00 257.16 ? 8   LEU B C     1 
ATOM 1473 O O     . LEU B 2 8   ? 132.880 150.804 214.888 1.00 256.14 ? 8   LEU B O     1 
ATOM 1474 C CB    . LEU B 2 8   ? 132.277 150.802 211.702 1.00 255.98 ? 8   LEU B CB    1 
ATOM 1475 C CG    . LEU B 2 8   ? 132.027 149.902 210.490 1.00 254.84 ? 8   LEU B CG    1 
ATOM 1476 C CD1   . LEU B 2 8   ? 133.220 149.930 209.557 1.00 254.70 ? 8   LEU B CD1   1 
ATOM 1477 C CD2   . LEU B 2 8   ? 131.707 148.474 210.910 1.00 254.61 ? 8   LEU B CD2   1 
ATOM 1478 N N     . ALA B 2 9   ? 131.514 152.508 214.339 1.00 271.48 ? 9   ALA B N     1 
ATOM 1479 C CA    . ALA B 2 9   ? 132.001 153.350 215.427 1.00 271.78 ? 9   ALA B CA    1 
ATOM 1480 C C     . ALA B 2 9   ? 131.630 152.771 216.787 1.00 271.46 ? 9   ALA B C     1 
ATOM 1481 O O     . ALA B 2 9   ? 132.487 152.623 217.667 1.00 271.56 ? 9   ALA B O     1 
ATOM 1482 C CB    . ALA B 2 9   ? 131.450 154.768 215.275 1.00 272.01 ? 9   ALA B CB    1 
ATOM 1483 N N     . MET B 2 10  ? 130.353 152.432 216.980 1.00 268.63 ? 10  MET B N     1 
ATOM 1484 C CA    . MET B 2 10  ? 129.920 151.906 218.271 1.00 267.85 ? 10  MET B CA    1 
ATOM 1485 C C     . MET B 2 10  ? 130.541 150.545 218.552 1.00 267.20 ? 10  MET B C     1 
ATOM 1486 O O     . MET B 2 10  ? 130.879 150.237 219.701 1.00 267.78 ? 10  MET B O     1 
ATOM 1487 C CB    . MET B 2 10  ? 128.394 151.820 218.325 1.00 268.19 ? 10  MET B CB    1 
ATOM 1488 C CG    . MET B 2 10  ? 127.672 152.975 217.653 1.00 268.81 ? 10  MET B CG    1 
ATOM 1489 S SD    . MET B 2 10  ? 128.659 154.481 217.575 1.00 270.88 ? 10  MET B SD    1 
ATOM 1490 C CE    . MET B 2 10  ? 128.273 155.224 219.159 1.00 269.04 ? 10  MET B CE    1 
ATOM 1491 N N     . VAL B 2 11  ? 130.694 149.715 217.519 1.00 249.12 ? 11  VAL B N     1 
ATOM 1492 C CA    . VAL B 2 11  ? 131.270 148.388 217.712 1.00 248.95 ? 11  VAL B CA    1 
ATOM 1493 C C     . VAL B 2 11  ? 132.726 148.484 218.154 1.00 249.38 ? 11  VAL B C     1 
ATOM 1494 O O     . VAL B 2 11  ? 133.189 147.675 218.968 1.00 249.72 ? 11  VAL B O     1 
ATOM 1495 C CB    . VAL B 2 11  ? 131.112 147.557 216.426 1.00 248.02 ? 11  VAL B CB    1 
ATOM 1496 C CG1   . VAL B 2 11  ? 131.968 146.319 216.488 1.00 247.99 ? 11  VAL B CG1   1 
ATOM 1497 C CG2   . VAL B 2 11  ? 129.657 147.169 216.232 1.00 248.98 ? 11  VAL B CG2   1 
ATOM 1498 N N     . VAL B 2 12  ? 133.464 149.473 217.645 1.00 248.79 ? 12  VAL B N     1 
ATOM 1499 C CA    . VAL B 2 12  ? 134.860 149.651 218.036 1.00 248.73 ? 12  VAL B CA    1 
ATOM 1500 C C     . VAL B 2 12  ? 134.978 149.901 219.535 1.00 249.92 ? 12  VAL B C     1 
ATOM 1501 O O     . VAL B 2 12  ? 135.966 149.501 220.166 1.00 249.84 ? 12  VAL B O     1 
ATOM 1502 C CB    . VAL B 2 12  ? 135.491 150.789 217.206 1.00 248.29 ? 12  VAL B CB    1 
ATOM 1503 C CG1   . VAL B 2 12  ? 136.657 151.434 217.942 1.00 248.73 ? 12  VAL B CG1   1 
ATOM 1504 C CG2   . VAL B 2 12  ? 135.940 150.262 215.853 1.00 247.44 ? 12  VAL B CG2   1 
ATOM 1505 N N     . GLN B 2 13  ? 133.962 150.524 220.139 1.00 266.44 ? 13  GLN B N     1 
ATOM 1506 C CA    . GLN B 2 13  ? 133.966 150.795 221.574 1.00 266.86 ? 13  GLN B CA    1 
ATOM 1507 C C     . GLN B 2 13  ? 134.019 149.528 222.423 1.00 266.58 ? 13  GLN B C     1 
ATOM 1508 O O     . GLN B 2 13  ? 134.121 149.634 223.650 1.00 266.32 ? 13  GLN B O     1 
ATOM 1509 C CB    . GLN B 2 13  ? 132.730 151.616 221.951 1.00 266.84 ? 13  GLN B CB    1 
ATOM 1510 C CG    . GLN B 2 13  ? 132.995 152.737 222.943 1.00 266.46 ? 13  GLN B CG    1 
ATOM 1511 C CD    . GLN B 2 13  ? 134.163 153.615 222.539 1.00 266.53 ? 13  GLN B CD    1 
ATOM 1512 O OE1   . GLN B 2 13  ? 134.274 154.028 221.384 1.00 267.36 ? 13  GLN B OE1   1 
ATOM 1513 N NE2   . GLN B 2 13  ? 135.041 153.907 223.491 1.00 266.29 ? 13  GLN B NE2   1 
ATOM 1514 N N     . ASP B 2 14  ? 133.942 148.350 221.811 1.00 248.47 ? 14  ASP B N     1 
ATOM 1515 C CA    . ASP B 2 14  ? 134.108 147.105 222.545 1.00 246.97 ? 14  ASP B CA    1 
ATOM 1516 C C     . ASP B 2 14  ? 135.478 147.102 223.217 1.00 247.64 ? 14  ASP B C     1 
ATOM 1517 O O     . ASP B 2 14  ? 136.492 147.337 222.544 1.00 248.89 ? 14  ASP B O     1 
ATOM 1518 C CB    . ASP B 2 14  ? 133.968 145.920 221.584 1.00 245.95 ? 14  ASP B CB    1 
ATOM 1519 C CG    . ASP B 2 14  ? 134.128 144.560 222.263 1.00 245.52 ? 14  ASP B CG    1 
ATOM 1520 O OD1   . ASP B 2 14  ? 134.366 144.491 223.484 1.00 245.26 ? 14  ASP B OD1   1 
ATOM 1521 O OD2   . ASP B 2 14  ? 134.016 143.540 221.551 1.00 244.92 ? 14  ASP B OD2   1 
ATOM 1522 N N     . PRO B 2 15  ? 135.552 146.867 224.530 1.00 244.14 ? 15  PRO B N     1 
ATOM 1523 C CA    . PRO B 2 15  ? 136.863 146.855 225.200 1.00 244.55 ? 15  PRO B CA    1 
ATOM 1524 C C     . PRO B 2 15  ? 137.840 145.852 224.614 1.00 243.67 ? 15  PRO B C     1 
ATOM 1525 O O     . PRO B 2 15  ? 139.049 146.114 224.605 1.00 243.99 ? 15  PRO B O     1 
ATOM 1526 C CB    . PRO B 2 15  ? 136.504 146.517 226.652 1.00 244.68 ? 15  PRO B CB    1 
ATOM 1527 C CG    . PRO B 2 15  ? 135.115 147.034 226.815 1.00 244.04 ? 15  PRO B CG    1 
ATOM 1528 C CD    . PRO B 2 15  ? 134.436 146.826 225.492 1.00 243.27 ? 15  PRO B CD    1 
ATOM 1529 N N     . LEU B 2 16  ? 137.360 144.711 224.124 1.00 234.45 ? 16  LEU B N     1 
ATOM 1530 C CA    . LEU B 2 16  ? 138.197 143.760 223.408 1.00 234.51 ? 16  LEU B CA    1 
ATOM 1531 C C     . LEU B 2 16  ? 138.316 144.091 221.927 1.00 235.61 ? 16  LEU B C     1 
ATOM 1532 O O     . LEU B 2 16  ? 138.645 143.210 221.126 1.00 235.91 ? 16  LEU B O     1 
ATOM 1533 C CB    . LEU B 2 16  ? 137.663 142.339 223.595 1.00 233.36 ? 16  LEU B CB    1 
ATOM 1534 C CG    . LEU B 2 16  ? 137.946 141.762 224.980 1.00 233.68 ? 16  LEU B CG    1 
ATOM 1535 C CD1   . LEU B 2 16  ? 137.279 140.417 225.160 1.00 233.68 ? 16  LEU B CD1   1 
ATOM 1536 C CD2   . LEU B 2 16  ? 139.447 141.640 225.167 1.00 234.52 ? 16  LEU B CD2   1 
ATOM 1537 N N     . LEU B 2 17  ? 138.045 145.341 221.547 1.00 232.67 ? 17  LEU B N     1 
ATOM 1538 C CA    . LEU B 2 17  ? 138.180 145.756 220.158 1.00 231.44 ? 17  LEU B CA    1 
ATOM 1539 C C     . LEU B 2 17  ? 138.759 147.162 220.037 1.00 231.83 ? 17  LEU B C     1 
ATOM 1540 O O     . LEU B 2 17  ? 138.741 147.731 218.938 1.00 232.55 ? 17  LEU B O     1 
ATOM 1541 C CB    . LEU B 2 17  ? 136.823 145.678 219.452 1.00 230.92 ? 17  LEU B CB    1 
ATOM 1542 C CG    . LEU B 2 17  ? 136.819 145.447 217.943 1.00 230.79 ? 17  LEU B CG    1 
ATOM 1543 C CD1   . LEU B 2 17  ? 137.459 144.108 217.617 1.00 230.45 ? 17  LEU B CD1   1 
ATOM 1544 C CD2   . LEU B 2 17  ? 135.407 145.521 217.393 1.00 231.05 ? 17  LEU B CD2   1 
ATOM 1545 N N     . CYS B 2 18  ? 139.272 147.741 221.126 1.00 236.02 ? 18  CYS B N     1 
ATOM 1546 C CA    . CYS B 2 18  ? 139.768 149.112 221.088 1.00 236.73 ? 18  CYS B CA    1 
ATOM 1547 C C     . CYS B 2 18  ? 141.035 149.257 220.256 1.00 235.99 ? 18  CYS B C     1 
ATOM 1548 O O     . CYS B 2 18  ? 141.414 150.383 219.918 1.00 236.63 ? 18  CYS B O     1 
ATOM 1549 C CB    . CYS B 2 18  ? 140.027 149.616 222.509 1.00 237.38 ? 18  CYS B CB    1 
ATOM 1550 S SG    . CYS B 2 18  ? 138.595 149.562 223.607 1.00 239.53 ? 18  CYS B SG    1 
ATOM 1551 N N     . ASP B 2 19  ? 141.702 148.150 219.926 1.00 208.52 ? 19  ASP B N     1 
ATOM 1552 C CA    . ASP B 2 19  ? 142.930 148.233 219.141 1.00 208.13 ? 19  ASP B CA    1 
ATOM 1553 C C     . ASP B 2 19  ? 142.655 148.756 217.735 1.00 207.46 ? 19  ASP B C     1 
ATOM 1554 O O     . ASP B 2 19  ? 143.556 149.283 217.073 1.00 207.00 ? 19  ASP B O     1 
ATOM 1555 C CB    . ASP B 2 19  ? 143.597 146.858 219.079 1.00 207.07 ? 19  ASP B CB    1 
ATOM 1556 C CG    . ASP B 2 19  ? 145.102 146.943 218.898 1.00 207.13 ? 19  ASP B CG    1 
ATOM 1557 O OD1   . ASP B 2 19  ? 145.583 147.930 218.308 1.00 208.39 ? 19  ASP B OD1   1 
ATOM 1558 O OD2   . ASP B 2 19  ? 145.810 146.019 219.350 1.00 207.08 ? 19  ASP B OD2   1 
ATOM 1559 N N     . LEU B 2 20  ? 141.428 148.606 217.258 1.00 198.23 ? 20  LEU B N     1 
ATOM 1560 C CA    . LEU B 2 20  ? 141.139 148.886 215.856 1.00 196.88 ? 20  LEU B CA    1 
ATOM 1561 C C     . LEU B 2 20  ? 140.965 150.385 215.631 1.00 196.03 ? 20  LEU B C     1 
ATOM 1562 O O     . LEU B 2 20  ? 140.246 151.042 216.392 1.00 196.29 ? 20  LEU B O     1 
ATOM 1563 C CB    . LEU B 2 20  ? 139.892 148.130 215.408 1.00 196.95 ? 20  LEU B CB    1 
ATOM 1564 C CG    . LEU B 2 20  ? 140.155 146.754 214.787 1.00 197.53 ? 20  LEU B CG    1 
ATOM 1565 C CD1   . LEU B 2 20  ? 140.476 146.894 213.306 1.00 195.89 ? 20  LEU B CD1   1 
ATOM 1566 C CD2   . LEU B 2 20  ? 141.256 145.983 215.529 1.00 196.84 ? 20  LEU B CD2   1 
ATOM 1567 N N     . PRO B 2 21  ? 141.606 150.960 214.610 1.00 173.31 ? 21  PRO B N     1 
ATOM 1568 C CA    . PRO B 2 21  ? 141.547 152.414 214.351 1.00 172.25 ? 21  PRO B CA    1 
ATOM 1569 C C     . PRO B 2 21  ? 140.330 152.883 213.552 1.00 172.56 ? 21  PRO B C     1 
ATOM 1570 O O     . PRO B 2 21  ? 140.395 153.176 212.356 1.00 172.45 ? 21  PRO B O     1 
ATOM 1571 C CB    . PRO B 2 21  ? 142.841 152.661 213.576 1.00 172.21 ? 21  PRO B CB    1 
ATOM 1572 C CG    . PRO B 2 21  ? 143.050 151.391 212.812 1.00 171.72 ? 21  PRO B CG    1 
ATOM 1573 C CD    . PRO B 2 21  ? 142.502 150.269 213.666 1.00 173.55 ? 21  PRO B CD    1 
ATOM 1574 N N     . ILE B 2 22  ? 139.191 152.978 214.243 1.00 169.59 ? 22  ILE B N     1 
ATOM 1575 C CA    . ILE B 2 22  ? 137.941 153.476 213.671 1.00 169.52 ? 22  ILE B CA    1 
ATOM 1576 C C     . ILE B 2 22  ? 137.632 152.737 212.377 1.00 168.07 ? 22  ILE B C     1 
ATOM 1577 O O     . ILE B 2 22  ? 137.000 151.676 212.392 1.00 170.32 ? 22  ILE B O     1 
ATOM 1578 C CB    . ILE B 2 22  ? 137.987 154.999 213.440 1.00 168.60 ? 22  ILE B CB    1 
ATOM 1579 C CG1   . ILE B 2 22  ? 138.524 155.719 214.680 1.00 169.15 ? 22  ILE B CG1   1 
ATOM 1580 C CG2   . ILE B 2 22  ? 136.605 155.527 213.074 1.00 167.75 ? 22  ILE B CG2   1 
ATOM 1581 C CD1   . ILE B 2 22  ? 139.990 156.107 214.590 1.00 170.05 ? 22  ILE B CD1   1 
ATOM 1582 N N     . GLN B 2 23  ? 138.067 153.298 211.250 1.00 158.53 ? 23  GLN B N     1 
ATOM 1583 C CA    . GLN B 2 23  ? 137.924 152.613 209.973 1.00 159.34 ? 23  GLN B CA    1 
ATOM 1584 C C     . GLN B 2 23  ? 138.725 151.324 210.014 1.00 159.28 ? 23  GLN B C     1 
ATOM 1585 O O     . GLN B 2 23  ? 139.943 151.349 210.213 1.00 162.86 ? 23  GLN B O     1 
ATOM 1586 C CB    . GLN B 2 23  ? 138.395 153.505 208.828 1.00 161.08 ? 23  GLN B CB    1 
ATOM 1587 C CG    . GLN B 2 23  ? 137.695 153.246 207.506 1.00 164.63 ? 23  GLN B CG    1 
ATOM 1588 C CD    . GLN B 2 23  ? 136.188 153.360 207.602 1.00 164.51 ? 23  GLN B CD    1 
ATOM 1589 O OE1   . GLN B 2 23  ? 135.659 154.234 208.289 1.00 165.37 ? 23  GLN B OE1   1 
ATOM 1590 N NE2   . GLN B 2 23  ? 135.486 152.477 206.902 1.00 161.80 ? 23  GLN B NE2   1 
ATOM 1591 N N     . VAL B 2 24  ? 138.045 150.199 209.835 1.00 158.09 ? 24  VAL B N     1 
ATOM 1592 C CA    . VAL B 2 24  ? 138.631 148.889 210.073 1.00 159.22 ? 24  VAL B CA    1 
ATOM 1593 C C     . VAL B 2 24  ? 139.305 148.343 208.826 1.00 158.70 ? 24  VAL B C     1 
ATOM 1594 O O     . VAL B 2 24  ? 140.496 148.035 208.848 1.00 157.89 ? 24  VAL B O     1 
ATOM 1595 C CB    . VAL B 2 24  ? 137.555 147.916 210.601 1.00 164.53 ? 24  VAL B CB    1 
ATOM 1596 C CG1   . VAL B 2 24  ? 137.361 148.112 212.090 1.00 164.06 ? 24  VAL B CG1   1 
ATOM 1597 C CG2   . VAL B 2 24  ? 136.242 148.126 209.865 1.00 165.74 ? 24  VAL B CG2   1 
ATOM 1598 N N     . THR B 2 25  ? 138.554 148.226 207.726 1.00 144.83 ? 25  THR B N     1 
ATOM 1599 C CA    . THR B 2 25  ? 139.027 147.677 206.457 1.00 143.63 ? 25  THR B CA    1 
ATOM 1600 C C     . THR B 2 25  ? 139.458 146.220 206.598 1.00 143.46 ? 25  THR B C     1 
ATOM 1601 O O     . THR B 2 25  ? 139.712 145.742 207.705 1.00 144.80 ? 25  THR B O     1 
ATOM 1602 C CB    . THR B 2 25  ? 140.161 148.529 205.878 1.00 143.73 ? 25  THR B CB    1 
ATOM 1603 O OG1   . THR B 2 25  ? 141.388 148.207 206.535 1.00 145.05 ? 25  THR B OG1   1 
ATOM 1604 C CG2   . THR B 2 25  ? 139.868 150.010 206.040 1.00 144.59 ? 25  THR B CG2   1 
ATOM 1605 N N     . LEU B 2 26  ? 139.523 145.495 205.481 1.00 149.70 ? 26  LEU B N     1 
ATOM 1606 C CA    . LEU B 2 26  ? 139.705 144.048 205.553 1.00 151.01 ? 26  LEU B CA    1 
ATOM 1607 C C     . LEU B 2 26  ? 141.137 143.675 205.931 1.00 153.10 ? 26  LEU B C     1 
ATOM 1608 O O     . LEU B 2 26  ? 141.351 142.764 206.738 1.00 154.13 ? 26  LEU B O     1 
ATOM 1609 C CB    . LEU B 2 26  ? 139.303 143.415 204.217 1.00 151.54 ? 26  LEU B CB    1 
ATOM 1610 C CG    . LEU B 2 26  ? 138.864 141.948 204.087 1.00 151.67 ? 26  LEU B CG    1 
ATOM 1611 C CD1   . LEU B 2 26  ? 138.640 141.612 202.621 1.00 152.65 ? 26  LEU B CD1   1 
ATOM 1612 C CD2   . LEU B 2 26  ? 139.830 140.948 204.701 1.00 152.19 ? 26  LEU B CD2   1 
ATOM 1613 N N     . GLU B 2 27  ? 142.131 144.358 205.360 1.00 149.54 ? 27  GLU B N     1 
ATOM 1614 C CA    . GLU B 2 27  ? 143.514 143.928 205.555 1.00 148.55 ? 27  GLU B CA    1 
ATOM 1615 C C     . GLU B 2 27  ? 143.963 144.115 207.001 1.00 148.78 ? 27  GLU B C     1 
ATOM 1616 O O     . GLU B 2 27  ? 144.744 143.311 207.522 1.00 150.61 ? 27  GLU B O     1 
ATOM 1617 C CB    . GLU B 2 27  ? 144.447 144.668 204.591 1.00 149.08 ? 27  GLU B CB    1 
ATOM 1618 C CG    . GLU B 2 27  ? 144.700 146.159 204.864 1.00 149.80 ? 27  GLU B CG    1 
ATOM 1619 C CD    . GLU B 2 27  ? 143.474 147.051 204.726 1.00 150.73 ? 27  GLU B CD    1 
ATOM 1620 O OE1   . GLU B 2 27  ? 142.332 146.553 204.778 1.00 149.88 ? 27  GLU B OE1   1 
ATOM 1621 O OE2   . GLU B 2 27  ? 143.664 148.277 204.570 1.00 150.26 ? 27  GLU B OE2   1 
ATOM 1622 N N     . GLU B 2 28  ? 143.487 145.171 207.667 1.00 151.18 ? 28  GLU B N     1 
ATOM 1623 C CA    . GLU B 2 28  ? 143.889 145.400 209.052 1.00 150.86 ? 28  GLU B CA    1 
ATOM 1624 C C     . GLU B 2 28  ? 143.337 144.322 209.977 1.00 151.48 ? 28  GLU B C     1 
ATOM 1625 O O     . GLU B 2 28  ? 144.078 143.748 210.783 1.00 153.95 ? 28  GLU B O     1 
ATOM 1626 C CB    . GLU B 2 28  ? 143.454 146.791 209.514 1.00 149.73 ? 28  GLU B CB    1 
ATOM 1627 C CG    . GLU B 2 28  ? 143.707 147.883 208.494 1.00 152.77 ? 28  GLU B CG    1 
ATOM 1628 C CD    . GLU B 2 28  ? 143.291 149.253 208.987 1.00 152.32 ? 28  GLU B CD    1 
ATOM 1629 O OE1   . GLU B 2 28  ? 142.496 149.920 208.292 1.00 154.38 ? 28  GLU B OE1   1 
ATOM 1630 O OE2   . GLU B 2 28  ? 143.764 149.667 210.065 1.00 150.08 ? 28  GLU B OE2   1 
ATOM 1631 N N     . VAL B 2 29  ? 142.040 144.022 209.875 1.00 134.68 ? 29  VAL B N     1 
ATOM 1632 C CA    . VAL B 2 29  ? 141.471 142.992 210.737 1.00 131.52 ? 29  VAL B CA    1 
ATOM 1633 C C     . VAL B 2 29  ? 142.058 141.629 210.397 1.00 133.87 ? 29  VAL B C     1 
ATOM 1634 O O     . VAL B 2 29  ? 142.342 140.824 211.290 1.00 136.35 ? 29  VAL B O     1 
ATOM 1635 C CB    . VAL B 2 29  ? 139.934 142.983 210.646 1.00 130.92 ? 29  VAL B CB    1 
ATOM 1636 C CG1   . VAL B 2 29  ? 139.353 144.156 211.400 1.00 132.48 ? 29  VAL B CG1   1 
ATOM 1637 C CG2   . VAL B 2 29  ? 139.479 143.000 209.207 1.00 134.82 ? 29  VAL B CG2   1 
ATOM 1638 N N     . ASN B 2 30  ? 142.256 141.350 209.106 1.00 132.73 ? 30  ASN B N     1 
ATOM 1639 C CA    . ASN B 2 30  ? 142.809 140.059 208.709 1.00 133.32 ? 30  ASN B CA    1 
ATOM 1640 C C     . ASN B 2 30  ? 144.224 139.877 209.239 1.00 135.94 ? 30  ASN B C     1 
ATOM 1641 O O     . ASN B 2 30  ? 144.618 138.762 209.601 1.00 136.99 ? 30  ASN B O     1 
ATOM 1642 C CB    . ASN B 2 30  ? 142.792 139.917 207.190 1.00 131.61 ? 30  ASN B CB    1 
ATOM 1643 C CG    . ASN B 2 30  ? 143.064 138.499 206.739 1.00 132.11 ? 30  ASN B CG    1 
ATOM 1644 O OD1   . ASN B 2 30  ? 143.047 137.567 207.543 1.00 134.51 ? 30  ASN B OD1   1 
ATOM 1645 N ND2   . ASN B 2 30  ? 143.333 138.328 205.451 1.00 133.49 ? 30  ASN B ND2   1 
ATOM 1646 N N     . SER B 2 31  ? 145.009 140.954 209.277 1.00 142.89 ? 31  SER B N     1 
ATOM 1647 C CA    . SER B 2 31  ? 146.352 140.856 209.837 1.00 141.84 ? 31  SER B CA    1 
ATOM 1648 C C     . SER B 2 31  ? 146.301 140.483 211.312 1.00 139.45 ? 31  SER B C     1 
ATOM 1649 O O     . SER B 2 31  ? 147.084 139.647 211.777 1.00 139.78 ? 31  SER B O     1 
ATOM 1650 C CB    . SER B 2 31  ? 147.101 142.172 209.640 1.00 140.73 ? 31  SER B CB    1 
ATOM 1651 O OG    . SER B 2 31  ? 147.076 142.576 208.282 1.00 141.64 ? 31  SER B OG    1 
ATOM 1652 N N     . GLN B 2 32  ? 145.378 141.087 212.063 1.00 135.76 ? 32  GLN B N     1 
ATOM 1653 C CA    . GLN B 2 32  ? 145.258 140.767 213.480 1.00 135.23 ? 32  GLN B CA    1 
ATOM 1654 C C     . GLN B 2 32  ? 144.687 139.372 213.695 1.00 137.06 ? 32  GLN B C     1 
ATOM 1655 O O     . GLN B 2 32  ? 144.846 138.803 214.779 1.00 137.65 ? 32  GLN B O     1 
ATOM 1656 C CB    . GLN B 2 32  ? 144.402 141.817 214.187 1.00 135.55 ? 32  GLN B CB    1 
ATOM 1657 C CG    . GLN B 2 32  ? 144.810 143.243 213.863 1.00 135.60 ? 32  GLN B CG    1 
ATOM 1658 C CD    . GLN B 2 32  ? 144.661 144.186 215.038 1.00 136.38 ? 32  GLN B CD    1 
ATOM 1659 O OE1   . GLN B 2 32  ? 144.775 143.781 216.194 1.00 138.81 ? 32  GLN B OE1   1 
ATOM 1660 N NE2   . GLN B 2 32  ? 144.412 145.458 214.747 1.00 134.30 ? 32  GLN B NE2   1 
ATOM 1661 N N     . ILE B 2 33  ? 144.011 138.812 212.688 1.00 143.82 ? 33  ILE B N     1 
ATOM 1662 C CA    . ILE B 2 33  ? 143.597 137.414 212.768 1.00 144.20 ? 33  ILE B CA    1 
ATOM 1663 C C     . ILE B 2 33  ? 144.818 136.517 212.902 1.00 145.16 ? 33  ILE B C     1 
ATOM 1664 O O     . ILE B 2 33  ? 144.871 135.630 213.762 1.00 147.18 ? 33  ILE B O     1 
ATOM 1665 C CB    . ILE B 2 33  ? 142.755 137.024 211.539 1.00 145.01 ? 33  ILE B CB    1 
ATOM 1666 C CG1   . ILE B 2 33  ? 141.473 137.845 211.473 1.00 144.37 ? 33  ILE B CG1   1 
ATOM 1667 C CG2   . ILE B 2 33  ? 142.417 135.546 211.575 1.00 145.79 ? 33  ILE B CG2   1 
ATOM 1668 C CD1   . ILE B 2 33  ? 140.769 137.934 212.779 1.00 142.42 ? 33  ILE B CD1   1 
ATOM 1669 N N     . ALA B 2 34  ? 145.827 136.748 212.061 1.00 127.31 ? 34  ALA B N     1 
ATOM 1670 C CA    . ALA B 2 34  ? 147.036 135.939 212.132 1.00 128.38 ? 34  ALA B CA    1 
ATOM 1671 C C     . ALA B 2 34  ? 147.811 136.210 213.413 1.00 131.62 ? 34  ALA B C     1 
ATOM 1672 O O     . ALA B 2 34  ? 148.586 135.358 213.859 1.00 131.81 ? 34  ALA B O     1 
ATOM 1673 C CB    . ALA B 2 34  ? 147.911 136.192 210.907 1.00 125.93 ? 34  ALA B CB    1 
ATOM 1674 N N     . LEU B 2 35  ? 147.619 137.385 214.016 1.00 136.17 ? 35  LEU B N     1 
ATOM 1675 C CA    . LEU B 2 35  ? 148.221 137.653 215.318 1.00 134.58 ? 35  LEU B CA    1 
ATOM 1676 C C     . LEU B 2 35  ? 147.676 136.699 216.372 1.00 136.03 ? 35  LEU B C     1 
ATOM 1677 O O     . LEU B 2 35  ? 148.433 136.143 217.177 1.00 136.87 ? 35  LEU B O     1 
ATOM 1678 C CB    . LEU B 2 35  ? 147.970 139.104 215.727 1.00 133.86 ? 35  LEU B CB    1 
ATOM 1679 C CG    . LEU B 2 35  ? 148.743 140.183 214.970 1.00 134.13 ? 35  LEU B CG    1 
ATOM 1680 C CD1   . LEU B 2 35  ? 148.342 141.562 215.457 1.00 133.66 ? 35  LEU B CD1   1 
ATOM 1681 C CD2   . LEU B 2 35  ? 150.234 139.975 215.134 1.00 133.69 ? 35  LEU B CD2   1 
ATOM 1682 N N     . GLU B 2 36  ? 146.356 136.500 216.386 1.00 157.94 ? 36  GLU B N     1 
ATOM 1683 C CA    . GLU B 2 36  ? 145.773 135.515 217.289 1.00 159.42 ? 36  GLU B CA    1 
ATOM 1684 C C     . GLU B 2 36  ? 146.233 134.110 216.929 1.00 158.95 ? 36  GLU B C     1 
ATOM 1685 O O     . GLU B 2 36  ? 146.585 133.317 217.809 1.00 159.65 ? 36  GLU B O     1 
ATOM 1686 C CB    . GLU B 2 36  ? 144.248 135.606 217.252 1.00 159.33 ? 36  GLU B CB    1 
ATOM 1687 C CG    . GLU B 2 36  ? 143.705 137.023 217.158 1.00 160.06 ? 36  GLU B CG    1 
ATOM 1688 C CD    . GLU B 2 36  ? 143.981 137.851 218.399 1.00 161.75 ? 36  GLU B CD    1 
ATOM 1689 O OE1   . GLU B 2 36  ? 143.781 139.082 218.345 1.00 161.12 ? 36  GLU B OE1   1 
ATOM 1690 O OE2   . GLU B 2 36  ? 144.376 137.275 219.434 1.00 161.87 ? 36  GLU B OE2   1 
ATOM 1691 N N     . TYR B 2 37  ? 146.246 133.788 215.635 1.00 146.39 ? 37  TYR B N     1 
ATOM 1692 C CA    . TYR B 2 37  ? 146.740 132.497 215.180 1.00 146.41 ? 37  TYR B CA    1 
ATOM 1693 C C     . TYR B 2 37  ? 148.253 132.374 215.293 1.00 146.62 ? 37  TYR B C     1 
ATOM 1694 O O     . TYR B 2 37  ? 148.781 131.269 215.131 1.00 145.15 ? 37  TYR B O     1 
ATOM 1695 C CB    . TYR B 2 37  ? 146.310 132.254 213.734 1.00 147.35 ? 37  TYR B CB    1 
ATOM 1696 C CG    . TYR B 2 37  ? 145.131 131.322 213.600 1.00 147.46 ? 37  TYR B CG    1 
ATOM 1697 C CD1   . TYR B 2 37  ? 144.202 131.199 214.623 1.00 146.35 ? 37  TYR B CD1   1 
ATOM 1698 C CD2   . TYR B 2 37  ? 144.946 130.566 212.452 1.00 146.65 ? 37  TYR B CD2   1 
ATOM 1699 C CE1   . TYR B 2 37  ? 143.122 130.348 214.506 1.00 147.85 ? 37  TYR B CE1   1 
ATOM 1700 C CE2   . TYR B 2 37  ? 143.869 129.713 212.325 1.00 147.87 ? 37  TYR B CE2   1 
ATOM 1701 C CZ    . TYR B 2 37  ? 142.960 129.607 213.356 1.00 149.73 ? 37  TYR B CZ    1 
ATOM 1702 O OH    . TYR B 2 37  ? 141.885 128.758 213.236 1.00 149.53 ? 37  TYR B OH    1 
ATOM 1703 N N     . GLY B 2 38  ? 148.957 133.473 215.553 1.00 137.73 ? 38  GLY B N     1 
ATOM 1704 C CA    . GLY B 2 38  ? 150.396 133.448 215.673 1.00 136.39 ? 38  GLY B CA    1 
ATOM 1705 C C     . GLY B 2 38  ? 151.146 133.473 214.362 1.00 134.58 ? 38  GLY B C     1 
ATOM 1706 O O     . GLY B 2 38  ? 152.383 133.489 214.377 1.00 134.63 ? 38  GLY B O     1 
ATOM 1707 N N     . GLN B 2 39  ? 150.444 133.481 213.228 1.00 123.37 ? 39  GLN B N     1 
ATOM 1708 C CA    . GLN B 2 39  ? 151.130 133.496 211.942 1.00 123.07 ? 39  GLN B CA    1 
ATOM 1709 C C     . GLN B 2 39  ? 151.791 134.847 211.700 1.00 126.62 ? 39  GLN B C     1 
ATOM 1710 O O     . GLN B 2 39  ? 152.893 134.918 211.146 1.00 128.19 ? 39  GLN B O     1 
ATOM 1711 C CB    . GLN B 2 39  ? 150.142 133.163 210.821 1.00 121.26 ? 39  GLN B CB    1 
ATOM 1712 C CG    . GLN B 2 39  ? 150.661 133.284 209.377 1.00 125.17 ? 39  GLN B CG    1 
ATOM 1713 C CD    . GLN B 2 39  ? 152.128 132.908 209.200 1.00 126.69 ? 39  GLN B CD    1 
ATOM 1714 O OE1   . GLN B 2 39  ? 152.617 131.949 209.797 1.00 125.32 ? 39  GLN B OE1   1 
ATOM 1715 N NE2   . GLN B 2 39  ? 152.835 133.667 208.371 1.00 124.78 ? 39  GLN B NE2   1 
ATOM 1716 N N     . ALA B 2 40  ? 151.144 135.929 212.120 1.00 119.02 ? 40  ALA B N     1 
ATOM 1717 C CA    . ALA B 2 40  ? 151.690 137.257 211.907 1.00 115.12 ? 40  ALA B CA    1 
ATOM 1718 C C     . ALA B 2 40  ? 152.745 137.577 212.962 1.00 111.75 ? 40  ALA B C     1 
ATOM 1719 O O     . ALA B 2 40  ? 153.010 136.796 213.880 1.00 111.52 ? 40  ALA B O     1 
ATOM 1720 C CB    . ALA B 2 40  ? 150.577 138.302 211.920 1.00 113.97 ? 40  ALA B CB    1 
ATOM 1721 N N     . MET B 2 41  ? 153.368 138.743 212.814 1.00 101.37 ? 41  MET B N     1 
ATOM 1722 C CA    . MET B 2 41  ? 154.287 139.262 213.814 1.00 99.46  ? 41  MET B CA    1 
ATOM 1723 C C     . MET B 2 41  ? 154.369 140.770 213.647 1.00 98.54  ? 41  MET B C     1 
ATOM 1724 O O     . MET B 2 41  ? 154.271 141.283 212.530 1.00 98.40  ? 41  MET B O     1 
ATOM 1725 C CB    . MET B 2 41  ? 155.676 138.628 213.693 1.00 100.47 ? 41  MET B CB    1 
ATOM 1726 C CG    . MET B 2 41  ? 156.602 139.303 212.705 1.00 99.79  ? 41  MET B CG    1 
ATOM 1727 S SD    . MET B 2 41  ? 157.643 138.122 211.834 1.00 108.22 ? 41  MET B SD    1 
ATOM 1728 C CE    . MET B 2 41  ? 158.496 139.210 210.702 1.00 99.42  ? 41  MET B CE    1 
ATOM 1729 N N     . THR B 2 42  ? 154.521 141.473 214.763 1.00 92.18  ? 42  THR B N     1 
ATOM 1730 C CA    . THR B 2 42  ? 154.642 142.920 214.726 1.00 92.16  ? 42  THR B CA    1 
ATOM 1731 C C     . THR B 2 42  ? 156.108 143.319 214.694 1.00 99.34  ? 42  THR B C     1 
ATOM 1732 O O     . THR B 2 42  ? 156.914 142.848 215.500 1.00 105.00 ? 42  THR B O     1 
ATOM 1733 C CB    . THR B 2 42  ? 153.962 143.554 215.937 1.00 87.70  ? 42  THR B CB    1 
ATOM 1734 O OG1   . THR B 2 42  ? 152.672 142.964 216.123 1.00 96.47  ? 42  THR B OG1   1 
ATOM 1735 C CG2   . THR B 2 42  ? 153.799 145.046 215.730 1.00 86.95  ? 42  THR B CG2   1 
ATOM 1736 N N     . VAL B 2 43  ? 156.451 144.184 213.747 1.00 91.65  ? 43  VAL B N     1 
ATOM 1737 C CA    . VAL B 2 43  ? 157.795 144.730 213.626 1.00 87.35  ? 43  VAL B CA    1 
ATOM 1738 C C     . VAL B 2 43  ? 157.699 146.228 213.857 1.00 90.19  ? 43  VAL B C     1 
ATOM 1739 O O     . VAL B 2 43  ? 157.098 146.948 213.050 1.00 97.08  ? 43  VAL B O     1 
ATOM 1740 C CB    . VAL B 2 43  ? 158.418 144.416 212.260 1.00 87.22  ? 43  VAL B CB    1 
ATOM 1741 C CG1   . VAL B 2 43  ? 159.722 145.157 212.095 1.00 91.61  ? 43  VAL B CG1   1 
ATOM 1742 C CG2   . VAL B 2 43  ? 158.639 142.926 212.126 1.00 91.07  ? 43  VAL B CG2   1 
ATOM 1743 N N     . ARG B 2 44  ? 158.271 146.693 214.961 1.00 95.66  ? 44  ARG B N     1 
ATOM 1744 C CA    . ARG B 2 44  ? 158.221 148.106 215.290 1.00 92.92  ? 44  ARG B CA    1 
ATOM 1745 C C     . ARG B 2 44  ? 159.234 148.882 214.464 1.00 96.69  ? 44  ARG B C     1 
ATOM 1746 O O     . ARG B 2 44  ? 160.370 148.440 214.268 1.00 100.11 ? 44  ARG B O     1 
ATOM 1747 C CB    . ARG B 2 44  ? 158.492 148.325 216.776 1.00 93.19  ? 44  ARG B CB    1 
ATOM 1748 C CG    . ARG B 2 44  ? 157.527 147.621 217.699 1.00 97.73  ? 44  ARG B CG    1 
ATOM 1749 C CD    . ARG B 2 44  ? 158.263 147.013 218.878 1.00 97.64  ? 44  ARG B CD    1 
ATOM 1750 N NE    . ARG B 2 44  ? 159.102 147.986 219.566 1.00 104.06 ? 44  ARG B NE    1 
ATOM 1751 C CZ    . ARG B 2 44  ? 158.647 149.002 220.287 1.00 103.86 ? 44  ARG B CZ    1 
ATOM 1752 N NH1   . ARG B 2 44  ? 157.351 149.218 220.438 1.00 101.53 ? 44  ARG B NH1   1 
ATOM 1753 N NH2   . ARG B 2 44  ? 159.516 149.824 220.869 1.00 103.48 ? 44  ARG B NH2   1 
ATOM 1754 N N     . VAL B 2 45  ? 158.809 150.037 213.965 1.00 96.35  ? 45  VAL B N     1 
ATOM 1755 C CA    . VAL B 2 45  ? 159.693 150.994 213.316 1.00 100.54 ? 45  VAL B CA    1 
ATOM 1756 C C     . VAL B 2 45  ? 159.557 152.318 214.050 1.00 107.19 ? 45  VAL B C     1 
ATOM 1757 O O     . VAL B 2 45  ? 158.440 152.768 214.330 1.00 108.20 ? 45  VAL B O     1 
ATOM 1758 C CB    . VAL B 2 45  ? 159.375 151.152 211.819 1.00 90.48  ? 45  VAL B CB    1 
ATOM 1759 C CG1   . VAL B 2 45  ? 159.724 149.885 211.078 1.00 92.67  ? 45  VAL B CG1   1 
ATOM 1760 C CG2   . VAL B 2 45  ? 157.917 151.476 211.615 1.00 96.67  ? 45  VAL B CG2   1 
ATOM 1761 N N     . CYS B 2 46  ? 160.691 152.920 214.392 1.00 106.61 ? 46  CYS B N     1 
ATOM 1762 C CA    . CYS B 2 46  ? 160.722 154.210 215.063 1.00 101.38 ? 46  CYS B CA    1 
ATOM 1763 C C     . CYS B 2 46  ? 161.328 155.240 214.126 1.00 101.07 ? 46  CYS B C     1 
ATOM 1764 O O     . CYS B 2 46  ? 162.435 155.047 213.614 1.00 98.63  ? 46  CYS B O     1 
ATOM 1765 C CB    . CYS B 2 46  ? 161.516 154.144 216.367 1.00 105.58 ? 46  CYS B CB    1 
ATOM 1766 S SG    . CYS B 2 46  ? 161.222 152.677 217.367 1.00 121.93 ? 46  CYS B SG    1 
ATOM 1767 N N     . LYS B 2 47  ? 160.600 156.326 213.905 1.00 93.29  ? 47  LYS B N     1 
ATOM 1768 C CA    . LYS B 2 47  ? 161.163 157.458 213.200 1.00 92.06  ? 47  LYS B CA    1 
ATOM 1769 C C     . LYS B 2 47  ? 162.242 158.114 214.057 1.00 97.55  ? 47  LYS B C     1 
ATOM 1770 O O     . LYS B 2 47  ? 162.320 157.908 215.270 1.00 98.05  ? 47  LYS B O     1 
ATOM 1771 C CB    . LYS B 2 47  ? 160.067 158.459 212.851 1.00 87.12  ? 47  LYS B CB    1 
ATOM 1772 C CG    . LYS B 2 47  ? 158.818 157.820 212.285 1.00 83.23  ? 47  LYS B CG    1 
ATOM 1773 C CD    . LYS B 2 47  ? 157.638 158.767 212.356 1.00 85.97  ? 47  LYS B CD    1 
ATOM 1774 C CE    . LYS B 2 47  ? 157.623 159.724 211.186 1.00 86.36  ? 47  LYS B CE    1 
ATOM 1775 N NZ    . LYS B 2 47  ? 157.645 158.992 209.895 1.00 94.26  ? 47  LYS B NZ    1 
ATOM 1776 N N     . MET B 2 48  ? 163.087 158.914 213.409 1.00 85.73  ? 48  MET B N     1 
ATOM 1777 C CA    . MET B 2 48  ? 164.227 159.494 214.107 1.00 87.98  ? 48  MET B CA    1 
ATOM 1778 C C     . MET B 2 48  ? 163.831 160.524 215.155 1.00 81.98  ? 48  MET B C     1 
ATOM 1779 O O     . MET B 2 48  ? 164.688 160.928 215.946 1.00 87.01  ? 48  MET B O     1 
ATOM 1780 C CB    . MET B 2 48  ? 165.198 160.110 213.104 1.00 92.27  ? 48  MET B CB    1 
ATOM 1781 C CG    . MET B 2 48  ? 165.784 159.155 212.051 1.00 89.77  ? 48  MET B CG    1 
ATOM 1782 S SD    . MET B 2 48  ? 166.656 157.664 212.602 1.00 84.39  ? 48  MET B SD    1 
ATOM 1783 C CE    . MET B 2 48  ? 165.342 156.511 212.993 1.00 86.82  ? 48  MET B CE    1 
ATOM 1784 N N     . ASP B 2 49  ? 162.576 160.962 215.186 1.00 83.12  ? 49  ASP B N     1 
ATOM 1785 C CA    . ASP B 2 49  ? 162.110 161.814 216.270 1.00 85.58  ? 49  ASP B CA    1 
ATOM 1786 C C     . ASP B 2 49  ? 161.530 161.018 217.430 1.00 95.05  ? 49  ASP B C     1 
ATOM 1787 O O     . ASP B 2 49  ? 161.011 161.618 218.376 1.00 96.18  ? 49  ASP B O     1 
ATOM 1788 C CB    . ASP B 2 49  ? 161.073 162.818 215.762 1.00 86.92  ? 49  ASP B CB    1 
ATOM 1789 C CG    . ASP B 2 49  ? 159.930 162.155 215.043 1.00 95.88  ? 49  ASP B CG    1 
ATOM 1790 O OD1   . ASP B 2 49  ? 160.052 160.956 214.729 1.00 106.95 ? 49  ASP B OD1   1 
ATOM 1791 O OD2   . ASP B 2 49  ? 158.909 162.830 214.791 1.00 100.04 ? 49  ASP B OD2   1 
ATOM 1792 N N     . GLY B 2 50  ? 161.596 159.688 217.376 1.00 102.18 ? 50  GLY B N     1 
ATOM 1793 C CA    . GLY B 2 50  ? 161.187 158.835 218.466 1.00 95.84  ? 50  GLY B CA    1 
ATOM 1794 C C     . GLY B 2 50  ? 159.822 158.201 218.304 1.00 98.30  ? 50  GLY B C     1 
ATOM 1795 O O     . GLY B 2 50  ? 159.525 157.223 218.999 1.00 104.03 ? 50  GLY B O     1 
ATOM 1796 N N     . GLU B 2 51  ? 158.988 158.726 217.412 1.00 97.84  ? 51  GLU B N     1 
ATOM 1797 C CA    . GLU B 2 51  ? 157.660 158.165 217.216 1.00 96.93  ? 51  GLU B CA    1 
ATOM 1798 C C     . GLU B 2 51  ? 157.762 156.764 216.628 1.00 97.88  ? 51  GLU B C     1 
ATOM 1799 O O     . GLU B 2 51  ? 158.543 156.514 215.707 1.00 94.07  ? 51  GLU B O     1 
ATOM 1800 C CB    . GLU B 2 51  ? 156.833 159.066 216.302 1.00 93.52  ? 51  GLU B CB    1 
ATOM 1801 C CG    . GLU B 2 51  ? 155.823 158.328 215.445 1.00 102.70 ? 51  GLU B CG    1 
ATOM 1802 C CD    . GLU B 2 51  ? 154.771 159.249 214.863 1.00 106.72 ? 51  GLU B CD    1 
ATOM 1803 O OE1   . GLU B 2 51  ? 154.644 160.391 215.352 1.00 106.72 ? 51  GLU B OE1   1 
ATOM 1804 O OE2   . GLU B 2 51  ? 154.072 158.831 213.917 1.00 104.76 ? 51  GLU B OE2   1 
ATOM 1805 N N     . VAL B 2 52  ? 156.968 155.847 217.171 1.00 106.62 ? 52  VAL B N     1 
ATOM 1806 C CA    . VAL B 2 52  ? 157.002 154.441 216.789 1.00 106.04 ? 52  VAL B CA    1 
ATOM 1807 C C     . VAL B 2 52  ? 155.695 154.085 216.100 1.00 109.79 ? 52  VAL B C     1 
ATOM 1808 O O     . VAL B 2 52  ? 154.618 154.526 216.520 1.00 111.01 ? 52  VAL B O     1 
ATOM 1809 C CB    . VAL B 2 52  ? 157.241 153.530 218.007 1.00 101.39 ? 52  VAL B CB    1 
ATOM 1810 C CG1   . VAL B 2 52  ? 157.690 152.149 217.554 1.00 100.13 ? 52  VAL B CG1   1 
ATOM 1811 C CG2   . VAL B 2 52  ? 158.258 154.153 218.941 1.00 104.33 ? 52  VAL B CG2   1 
ATOM 1812 N N     . MET B 2 53  ? 155.793 153.295 215.034 1.00 106.02 ? 53  MET B N     1 
ATOM 1813 C CA    . MET B 2 53  ? 154.627 152.787 214.324 1.00 103.24 ? 53  MET B CA    1 
ATOM 1814 C C     . MET B 2 53  ? 154.689 151.266 214.267 1.00 105.10 ? 53  MET B C     1 
ATOM 1815 O O     . MET B 2 53  ? 155.658 150.708 213.726 1.00 107.19 ? 53  MET B O     1 
ATOM 1816 C CB    . MET B 2 53  ? 154.539 153.388 212.920 1.00 95.90  ? 53  MET B CB    1 
ATOM 1817 C CG    . MET B 2 53  ? 155.327 154.677 212.751 1.00 98.45  ? 53  MET B CG    1 
ATOM 1818 S SD    . MET B 2 53  ? 155.255 155.368 211.087 1.00 105.38 ? 53  MET B SD    1 
ATOM 1819 C CE    . MET B 2 53  ? 156.302 154.241 210.181 1.00 98.86  ? 53  MET B CE    1 
ATOM 1820 N N     . PRO B 2 54  ? 153.703 150.559 214.825 1.00 93.19  ? 54  PRO B N     1 
ATOM 1821 C CA    . PRO B 2 54  ? 153.772 149.093 214.887 1.00 91.04  ? 54  PRO B CA    1 
ATOM 1822 C C     . PRO B 2 54  ? 153.316 148.401 213.612 1.00 92.53  ? 54  PRO B C     1 
ATOM 1823 O O     . PRO B 2 54  ? 152.159 147.987 213.505 1.00 97.65  ? 54  PRO B O     1 
ATOM 1824 C CB    . PRO B 2 54  ? 152.846 148.758 216.059 1.00 94.84  ? 54  PRO B CB    1 
ATOM 1825 C CG    . PRO B 2 54  ? 151.839 149.860 216.055 1.00 92.09  ? 54  PRO B CG    1 
ATOM 1826 C CD    . PRO B 2 54  ? 152.518 151.091 215.519 1.00 93.18  ? 54  PRO B CD    1 
ATOM 1827 N N     . VAL B 2 55  ? 154.214 148.270 212.638 1.00 86.84  ? 55  VAL B N     1 
ATOM 1828 C CA    . VAL B 2 55  ? 153.880 147.585 211.397 1.00 83.67  ? 55  VAL B CA    1 
ATOM 1829 C C     . VAL B 2 55  ? 153.756 146.088 211.649 1.00 86.88  ? 55  VAL B C     1 
ATOM 1830 O O     . VAL B 2 55  ? 154.586 145.485 212.343 1.00 90.69  ? 55  VAL B O     1 
ATOM 1831 C CB    . VAL B 2 55  ? 154.940 147.892 210.327 1.00 84.94  ? 55  VAL B CB    1 
ATOM 1832 C CG1   . VAL B 2 55  ? 154.993 146.790 209.289 1.00 89.94  ? 55  VAL B CG1   1 
ATOM 1833 C CG2   . VAL B 2 55  ? 154.647 149.232 209.676 1.00 93.67  ? 55  VAL B CG2   1 
ATOM 1834 N N     . VAL B 2 56  ? 152.711 145.480 211.090 1.00 82.39  ? 56  VAL B N     1 
ATOM 1835 C CA    . VAL B 2 56  ? 152.412 144.064 211.277 1.00 82.89  ? 56  VAL B CA    1 
ATOM 1836 C C     . VAL B 2 56  ? 152.544 143.345 209.941 1.00 85.89  ? 56  VAL B C     1 
ATOM 1837 O O     . VAL B 2 56  ? 151.994 143.792 208.928 1.00 90.37  ? 56  VAL B O     1 
ATOM 1838 C CB    . VAL B 2 56  ? 151.010 143.859 211.875 1.00 80.59  ? 56  VAL B CB    1 
ATOM 1839 C CG1   . VAL B 2 56  ? 149.987 144.710 211.144 1.00 81.65  ? 56  VAL B CG1   1 
ATOM 1840 C CG2   . VAL B 2 56  ? 150.620 142.394 211.815 1.00 82.02  ? 56  VAL B CG2   1 
ATOM 1841 N N     . VAL B 2 57  ? 153.279 142.233 209.941 1.00 86.61  ? 57  VAL B N     1 
ATOM 1842 C CA    . VAL B 2 57  ? 153.458 141.393 208.765 1.00 86.80  ? 57  VAL B CA    1 
ATOM 1843 C C     . VAL B 2 57  ? 153.296 139.938 209.187 1.00 91.57  ? 57  VAL B C     1 
ATOM 1844 O O     . VAL B 2 57  ? 153.142 139.624 210.366 1.00 95.11  ? 57  VAL B O     1 
ATOM 1845 C CB    . VAL B 2 57  ? 154.830 141.603 208.096 1.00 87.17  ? 57  VAL B CB    1 
ATOM 1846 C CG1   . VAL B 2 57  ? 154.949 143.009 207.552 1.00 87.49  ? 57  VAL B CG1   1 
ATOM 1847 C CG2   . VAL B 2 57  ? 155.943 141.314 209.081 1.00 91.41  ? 57  VAL B CG2   1 
ATOM 1848 N N     . VAL B 2 58  ? 153.328 139.044 208.200 1.00 96.56  ? 58  VAL B N     1 
ATOM 1849 C CA    . VAL B 2 58  ? 153.256 137.610 208.460 1.00 95.62  ? 58  VAL B CA    1 
ATOM 1850 C C     . VAL B 2 58  ? 154.644 137.098 208.816 1.00 98.36  ? 58  VAL B C     1 
ATOM 1851 O O     . VAL B 2 58  ? 155.642 137.793 208.603 1.00 102.85 ? 58  VAL B O     1 
ATOM 1852 C CB    . VAL B 2 58  ? 152.681 136.852 207.251 1.00 96.92  ? 58  VAL B CB    1 
ATOM 1853 C CG1   . VAL B 2 58  ? 151.355 137.460 206.828 1.00 100.21 ? 58  VAL B CG1   1 
ATOM 1854 C CG2   . VAL B 2 58  ? 153.670 136.857 206.103 1.00 96.08  ? 58  VAL B CG2   1 
ATOM 1855 N N     . GLN B 2 59  ? 154.720 135.882 209.365 1.00 108.38 ? 59  GLN B N     1 
ATOM 1856 C CA    . GLN B 2 59  ? 156.017 135.324 209.739 1.00 111.16 ? 59  GLN B CA    1 
ATOM 1857 C C     . GLN B 2 59  ? 156.916 135.145 208.526 1.00 112.87 ? 59  GLN B C     1 
ATOM 1858 O O     . GLN B 2 59  ? 158.113 135.447 208.581 1.00 111.70 ? 59  GLN B O     1 
ATOM 1859 C CB    . GLN B 2 59  ? 155.839 133.989 210.460 1.00 106.60 ? 59  GLN B CB    1 
ATOM 1860 C CG    . GLN B 2 59  ? 155.754 134.110 211.969 1.00 106.55 ? 59  GLN B CG    1 
ATOM 1861 C CD    . GLN B 2 59  ? 154.870 133.049 212.587 1.00 113.47 ? 59  GLN B CD    1 
ATOM 1862 O OE1   . GLN B 2 59  ? 154.422 132.127 211.908 1.00 114.06 ? 59  GLN B OE1   1 
ATOM 1863 N NE2   . GLN B 2 59  ? 154.613 133.174 213.883 1.00 114.01 ? 59  GLN B NE2   1 
ATOM 1864 N N     . SER B 2 60  ? 156.360 134.658 207.423 1.00 106.58 ? 60  SER B N     1 
ATOM 1865 C CA    . SER B 2 60  ? 157.136 134.449 206.211 1.00 108.26 ? 60  SER B CA    1 
ATOM 1866 C C     . SER B 2 60  ? 157.206 135.689 205.340 1.00 111.35 ? 60  SER B C     1 
ATOM 1867 O O     . SER B 2 60  ? 157.492 135.576 204.142 1.00 117.48 ? 60  SER B O     1 
ATOM 1868 C CB    . SER B 2 60  ? 156.562 133.275 205.415 1.00 109.68 ? 60  SER B CB    1 
ATOM 1869 O OG    . SER B 2 60  ? 156.910 132.042 206.019 1.00 110.55 ? 60  SER B OG    1 
ATOM 1870 N N     . ALA B 2 61  ? 156.956 136.863 205.913 1.00 98.97  ? 61  ALA B N     1 
ATOM 1871 C CA    . ALA B 2 61  ? 157.017 138.092 205.140 1.00 99.87  ? 61  ALA B CA    1 
ATOM 1872 C C     . ALA B 2 61  ? 158.448 138.377 204.714 1.00 98.86  ? 61  ALA B C     1 
ATOM 1873 O O     . ALA B 2 61  ? 159.390 138.222 205.495 1.00 104.14 ? 61  ALA B O     1 
ATOM 1874 C CB    . ALA B 2 61  ? 156.474 139.260 205.957 1.00 98.96  ? 61  ALA B CB    1 
ATOM 1875 N N     . THR B 2 62  ? 158.610 138.792 203.466 1.00 97.87  ? 62  THR B N     1 
ATOM 1876 C CA    . THR B 2 62  ? 159.923 139.134 202.952 1.00 103.61 ? 62  THR B CA    1 
ATOM 1877 C C     . THR B 2 62  ? 160.199 140.617 203.181 1.00 103.86 ? 62  THR B C     1 
ATOM 1878 O O     . THR B 2 62  ? 159.310 141.393 203.541 1.00 105.83 ? 62  THR B O     1 
ATOM 1879 C CB    . THR B 2 62  ? 160.027 138.776 201.471 1.00 105.41 ? 62  THR B CB    1 
ATOM 1880 O OG1   . THR B 2 62  ? 161.395 138.526 201.136 1.00 107.09 ? 62  THR B OG1   1 
ATOM 1881 C CG2   . THR B 2 62  ? 159.490 139.902 200.602 1.00 101.53 ? 62  THR B CG2   1 
ATOM 1882 N N     . VAL B 2 63  ? 161.460 141.005 202.975 1.00 97.19  ? 63  VAL B N     1 
ATOM 1883 C CA    . VAL B 2 63  ? 161.863 142.385 203.233 1.00 94.55  ? 63  VAL B CA    1 
ATOM 1884 C C     . VAL B 2 63  ? 161.037 143.341 202.389 1.00 93.99  ? 63  VAL B C     1 
ATOM 1885 O O     . VAL B 2 63  ? 160.497 144.333 202.891 1.00 94.19  ? 63  VAL B O     1 
ATOM 1886 C CB    . VAL B 2 63  ? 163.367 142.570 202.970 1.00 90.13  ? 63  VAL B CB    1 
ATOM 1887 C CG1   . VAL B 2 63  ? 163.721 144.048 203.006 1.00 94.08  ? 63  VAL B CG1   1 
ATOM 1888 C CG2   . VAL B 2 63  ? 164.184 141.802 203.991 1.00 92.99  ? 63  VAL B CG2   1 
ATOM 1889 N N     . LEU B 2 64  ? 160.909 143.043 201.096 1.00 93.02  ? 64  LEU B N     1 
ATOM 1890 C CA    . LEU B 2 64  ? 160.106 143.884 200.219 1.00 90.50  ? 64  LEU B CA    1 
ATOM 1891 C C     . LEU B 2 64  ? 158.651 143.914 200.659 1.00 86.12  ? 64  LEU B C     1 
ATOM 1892 O O     . LEU B 2 64  ? 157.996 144.955 200.550 1.00 87.04  ? 64  LEU B O     1 
ATOM 1893 C CB    . LEU B 2 64  ? 160.251 143.400 198.774 1.00 86.33  ? 64  LEU B CB    1 
ATOM 1894 C CG    . LEU B 2 64  ? 159.313 143.825 197.646 1.00 88.18  ? 64  LEU B CG    1 
ATOM 1895 C CD1   . LEU B 2 64  ? 160.027 143.628 196.327 1.00 94.26  ? 64  LEU B CD1   1 
ATOM 1896 C CD2   . LEU B 2 64  ? 158.056 142.981 197.650 1.00 95.00  ? 64  LEU B CD2   1 
ATOM 1897 N N     . ASP B 2 65  ? 158.129 142.788 201.146 1.00 93.38  ? 65  ASP B N     1 
ATOM 1898 C CA    . ASP B 2 65  ? 156.770 142.779 201.673 1.00 95.42  ? 65  ASP B CA    1 
ATOM 1899 C C     . ASP B 2 65  ? 156.680 143.701 202.882 1.00 96.02  ? 65  ASP B C     1 
ATOM 1900 O O     . ASP B 2 65  ? 155.727 144.480 203.009 1.00 96.21  ? 65  ASP B O     1 
ATOM 1901 C CB    . ASP B 2 65  ? 156.371 141.331 202.002 1.00 94.37  ? 65  ASP B CB    1 
ATOM 1902 C CG    . ASP B 2 65  ? 155.220 141.201 203.009 1.00 103.88 ? 65  ASP B CG    1 
ATOM 1903 O OD1   . ASP B 2 65  ? 154.907 140.044 203.351 1.00 107.04 ? 65  ASP B OD1   1 
ATOM 1904 O OD2   . ASP B 2 65  ? 154.563 142.186 203.402 1.00 108.25 ? 65  ASP B OD2   1 
ATOM 1905 N N     . LEU B 2 66  ? 157.686 143.651 203.757 1.00 88.60  ? 66  LEU B N     1 
ATOM 1906 C CA    . LEU B 2 66  ? 157.734 144.570 204.889 1.00 89.18  ? 66  LEU B CA    1 
ATOM 1907 C C     . LEU B 2 66  ? 157.701 146.016 204.420 1.00 87.38  ? 66  LEU B C     1 
ATOM 1908 O O     . LEU B 2 66  ? 157.064 146.868 205.050 1.00 86.87  ? 66  LEU B O     1 
ATOM 1909 C CB    . LEU B 2 66  ? 158.990 144.307 205.718 1.00 86.84  ? 66  LEU B CB    1 
ATOM 1910 C CG    . LEU B 2 66  ? 159.363 145.322 206.799 1.00 79.87  ? 66  LEU B CG    1 
ATOM 1911 C CD1   . LEU B 2 66  ? 158.211 145.581 207.755 1.00 82.74  ? 66  LEU B CD1   1 
ATOM 1912 C CD2   . LEU B 2 66  ? 160.582 144.853 207.555 1.00 83.94  ? 66  LEU B CD2   1 
ATOM 1913 N N     . LYS B 2 67  ? 158.377 146.311 203.308 1.00 79.89  ? 67  LYS B N     1 
ATOM 1914 C CA    . LYS B 2 67  ? 158.396 147.673 202.790 1.00 75.22  ? 67  LYS B CA    1 
ATOM 1915 C C     . LYS B 2 67  ? 156.988 148.149 202.462 1.00 83.71  ? 67  LYS B C     1 
ATOM 1916 O O     . LYS B 2 67  ? 156.582 149.242 202.869 1.00 84.82  ? 67  LYS B O     1 
ATOM 1917 C CB    . LYS B 2 67  ? 159.297 147.741 201.559 1.00 73.89  ? 67  LYS B CB    1 
ATOM 1918 C CG    . LYS B 2 67  ? 160.694 147.214 201.816 1.00 75.29  ? 67  LYS B CG    1 
ATOM 1919 C CD    . LYS B 2 67  ? 161.763 148.267 201.632 1.00 77.60  ? 67  LYS B CD    1 
ATOM 1920 C CE    . LYS B 2 67  ? 161.872 148.674 200.180 1.00 82.63  ? 67  LYS B CE    1 
ATOM 1921 N NZ    . LYS B 2 67  ? 162.978 149.639 199.960 1.00 80.11  ? 67  LYS B NZ    1 
ATOM 1922 N N     . LYS B 2 68  ? 156.215 147.324 201.750 1.00 89.70  ? 68  LYS B N     1 
ATOM 1923 C CA    . LYS B 2 68  ? 154.844 147.704 201.424 1.00 85.32  ? 68  LYS B CA    1 
ATOM 1924 C C     . LYS B 2 68  ? 153.993 147.849 202.674 1.00 89.89  ? 68  LYS B C     1 
ATOM 1925 O O     . LYS B 2 68  ? 153.095 148.697 202.719 1.00 91.77  ? 68  LYS B O     1 
ATOM 1926 C CB    . LYS B 2 68  ? 154.204 146.684 200.485 1.00 85.31  ? 68  LYS B CB    1 
ATOM 1927 C CG    . LYS B 2 68  ? 155.125 146.070 199.459 1.00 82.86  ? 68  LYS B CG    1 
ATOM 1928 C CD    . LYS B 2 68  ? 154.342 145.768 198.195 1.00 88.92  ? 68  LYS B CD    1 
ATOM 1929 C CE    . LYS B 2 68  ? 155.029 144.722 197.347 1.00 89.17  ? 68  LYS B CE    1 
ATOM 1930 N NZ    . LYS B 2 68  ? 154.721 143.344 197.816 1.00 90.07  ? 68  LYS B NZ    1 
ATOM 1931 N N     . ALA B 2 69  ? 154.251 147.026 203.692 1.00 79.78  ? 69  ALA B N     1 
ATOM 1932 C CA    . ALA B 2 69  ? 153.515 147.155 204.941 1.00 81.08  ? 69  ALA B CA    1 
ATOM 1933 C C     . ALA B 2 69  ? 153.729 148.530 205.553 1.00 82.74  ? 69  ALA B C     1 
ATOM 1934 O O     . ALA B 2 69  ? 152.784 149.150 206.055 1.00 85.95  ? 69  ALA B O     1 
ATOM 1935 C CB    . ALA B 2 69  ? 153.939 146.059 205.913 1.00 83.72  ? 69  ALA B CB    1 
ATOM 1936 N N     . ILE B 2 70  ? 154.966 149.028 205.512 1.00 80.25  ? 70  ILE B N     1 
ATOM 1937 C CA    . ILE B 2 70  ? 155.223 150.397 205.939 1.00 80.53  ? 70  ILE B CA    1 
ATOM 1938 C C     . ILE B 2 70  ? 154.461 151.373 205.057 1.00 84.60  ? 70  ILE B C     1 
ATOM 1939 O O     . ILE B 2 70  ? 153.818 152.304 205.552 1.00 86.90  ? 70  ILE B O     1 
ATOM 1940 C CB    . ILE B 2 70  ? 156.732 150.691 205.938 1.00 77.40  ? 70  ILE B CB    1 
ATOM 1941 C CG1   . ILE B 2 70  ? 157.490 149.568 206.639 1.00 73.12  ? 70  ILE B CG1   1 
ATOM 1942 C CG2   . ILE B 2 70  ? 157.011 152.012 206.621 1.00 81.29  ? 70  ILE B CG2   1 
ATOM 1943 C CD1   . ILE B 2 70  ? 158.982 149.756 206.639 1.00 81.86  ? 70  ILE B CD1   1 
ATOM 1944 N N     . GLN B 2 71  ? 154.504 151.167 203.739 1.00 87.84  ? 71  GLN B N     1 
ATOM 1945 C CA    . GLN B 2 71  ? 153.693 151.988 202.847 1.00 85.94  ? 71  GLN B CA    1 
ATOM 1946 C C     . GLN B 2 71  ? 152.223 151.878 203.210 1.00 93.75  ? 71  GLN B C     1 
ATOM 1947 O O     . GLN B 2 71  ? 151.516 152.886 203.300 1.00 93.85  ? 71  GLN B O     1 
ATOM 1948 C CB    . GLN B 2 71  ? 153.904 151.577 201.392 1.00 83.62  ? 71  GLN B CB    1 
ATOM 1949 C CG    . GLN B 2 71  ? 155.331 151.303 200.998 1.00 88.72  ? 71  GLN B CG    1 
ATOM 1950 C CD    . GLN B 2 71  ? 155.528 151.371 199.501 1.00 95.13  ? 71  GLN B CD    1 
ATOM 1951 O OE1   . GLN B 2 71  ? 155.087 152.315 198.850 1.00 97.96  ? 71  GLN B OE1   1 
ATOM 1952 N NE2   . GLN B 2 71  ? 156.190 150.365 198.945 1.00 97.44  ? 71  GLN B NE2   1 
ATOM 1953 N N     . ARG B 2 72  ? 151.749 150.654 203.441 1.00 101.07 ? 72  ARG B N     1 
ATOM 1954 C CA    . ARG B 2 72  ? 150.351 150.465 203.806 1.00 96.88  ? 72  ARG B CA    1 
ATOM 1955 C C     . ARG B 2 72  ? 150.038 151.149 205.130 1.00 97.36  ? 72  ARG B C     1 
ATOM 1956 O O     . ARG B 2 72  ? 149.003 151.809 205.271 1.00 102.58 ? 72  ARG B O     1 
ATOM 1957 C CB    . ARG B 2 72  ? 150.026 148.975 203.872 1.00 97.88  ? 72  ARG B CB    1 
ATOM 1958 C CG    . ARG B 2 72  ? 148.566 148.676 204.132 1.00 101.80 ? 72  ARG B CG    1 
ATOM 1959 C CD    . ARG B 2 72  ? 148.095 147.484 203.320 1.00 105.63 ? 72  ARG B CD    1 
ATOM 1960 N NE    . ARG B 2 72  ? 148.946 146.316 203.515 1.00 109.07 ? 72  ARG B NE    1 
ATOM 1961 C CZ    . ARG B 2 72  ? 149.818 145.864 202.624 1.00 106.89 ? 72  ARG B CZ    1 
ATOM 1962 N NH1   . ARG B 2 72  ? 149.983 146.461 201.456 1.00 104.11 ? 72  ARG B NH1   1 
ATOM 1963 N NH2   . ARG B 2 72  ? 150.543 144.788 202.914 1.00 103.42 ? 72  ARG B NH2   1 
ATOM 1964 N N     . TYR B 2 73  ? 150.933 151.013 206.112 1.00 89.78  ? 73  TYR B N     1 
ATOM 1965 C CA    . TYR B 2 73  ? 150.717 151.677 207.393 1.00 92.11  ? 73  TYR B CA    1 
ATOM 1966 C C     . TYR B 2 73  ? 150.772 153.191 207.242 1.00 89.42  ? 73  TYR B C     1 
ATOM 1967 O O     . TYR B 2 73  ? 149.873 153.905 207.702 1.00 91.17  ? 73  TYR B O     1 
ATOM 1968 C CB    . TYR B 2 73  ? 151.751 151.210 208.418 1.00 91.68  ? 73  TYR B CB    1 
ATOM 1969 C CG    . TYR B 2 73  ? 151.432 151.646 209.832 1.00 93.01  ? 73  TYR B CG    1 
ATOM 1970 C CD1   . TYR B 2 73  ? 151.719 152.932 210.263 1.00 91.30  ? 73  TYR B CD1   1 
ATOM 1971 C CD2   . TYR B 2 73  ? 150.847 150.773 210.735 1.00 99.78  ? 73  TYR B CD2   1 
ATOM 1972 C CE1   . TYR B 2 73  ? 151.425 153.339 211.543 1.00 90.62  ? 73  TYR B CE1   1 
ATOM 1973 C CE2   . TYR B 2 73  ? 150.554 151.172 212.025 1.00 100.07 ? 73  TYR B CE2   1 
ATOM 1974 C CZ    . TYR B 2 73  ? 150.848 152.457 212.422 1.00 94.83  ? 73  TYR B CZ    1 
ATOM 1975 O OH    . TYR B 2 73  ? 150.561 152.870 213.701 1.00 95.98  ? 73  TYR B OH    1 
ATOM 1976 N N     . VAL B 2 74  ? 151.827 153.700 206.603 1.00 83.96  ? 74  VAL B N     1 
ATOM 1977 C CA    . VAL B 2 74  ? 151.985 155.145 206.484 1.00 84.49  ? 74  VAL B CA    1 
ATOM 1978 C C     . VAL B 2 74  ? 150.847 155.738 205.673 1.00 87.76  ? 74  VAL B C     1 
ATOM 1979 O O     . VAL B 2 74  ? 150.242 156.738 206.072 1.00 88.06  ? 74  VAL B O     1 
ATOM 1980 C CB    . VAL B 2 74  ? 153.354 155.496 205.876 1.00 81.05  ? 74  VAL B CB    1 
ATOM 1981 C CG1   . VAL B 2 74  ? 153.453 156.989 205.659 1.00 84.29  ? 74  VAL B CG1   1 
ATOM 1982 C CG2   . VAL B 2 74  ? 154.466 155.041 206.792 1.00 85.20  ? 74  VAL B CG2   1 
ATOM 1983 N N     . GLN B 2 75  ? 150.521 155.124 204.535 1.00 99.10  ? 75  GLN B N     1 
ATOM 1984 C CA    . GLN B 2 75  ? 149.458 155.666 203.698 1.00 99.40  ? 75  GLN B CA    1 
ATOM 1985 C C     . GLN B 2 75  ? 148.135 155.680 204.449 1.00 103.05 ? 75  GLN B C     1 
ATOM 1986 O O     . GLN B 2 75  ? 147.396 156.668 204.409 1.00 106.56 ? 75  GLN B O     1 
ATOM 1987 C CB    . GLN B 2 75  ? 149.333 154.865 202.405 1.00 97.98  ? 75  GLN B CB    1 
ATOM 1988 C CG    . GLN B 2 75  ? 150.467 155.101 201.426 1.00 98.50  ? 75  GLN B CG    1 
ATOM 1989 C CD    . GLN B 2 75  ? 150.333 156.401 200.667 1.00 104.02 ? 75  GLN B CD    1 
ATOM 1990 O OE1   . GLN B 2 75  ? 149.369 157.144 200.846 1.00 102.82 ? 75  GLN B OE1   1 
ATOM 1991 N NE2   . GLN B 2 75  ? 151.302 156.682 199.807 1.00 106.07 ? 75  GLN B NE2   1 
ATOM 1992 N N     . LEU B 2 76  ? 147.831 154.599 205.166 1.00 100.89 ? 76  LEU B N     1 
ATOM 1993 C CA    . LEU B 2 76  ? 146.616 154.586 205.972 1.00 99.45  ? 76  LEU B CA    1 
ATOM 1994 C C     . LEU B 2 76  ? 146.670 155.663 207.046 1.00 98.91  ? 76  LEU B C     1 
ATOM 1995 O O     . LEU B 2 76  ? 145.651 156.284 207.368 1.00 99.13  ? 76  LEU B O     1 
ATOM 1996 C CB    . LEU B 2 76  ? 146.409 153.208 206.599 1.00 102.86 ? 76  LEU B CB    1 
ATOM 1997 C CG    . LEU B 2 76  ? 145.558 152.207 205.815 1.00 98.33  ? 76  LEU B CG    1 
ATOM 1998 C CD1   . LEU B 2 76  ? 144.085 152.478 206.050 1.00 99.64  ? 76  LEU B CD1   1 
ATOM 1999 C CD2   . LEU B 2 76  ? 145.874 152.226 204.330 1.00 97.45  ? 76  LEU B CD2   1 
ATOM 2000 N N     . LYS B 2 77  ? 147.858 155.909 207.601 1.00 100.49 ? 77  LYS B N     1 
ATOM 2001 C CA    . LYS B 2 77  ? 148.011 156.957 208.604 1.00 102.12 ? 77  LYS B CA    1 
ATOM 2002 C C     . LYS B 2 77  ? 147.679 158.325 208.027 1.00 101.09 ? 77  LYS B C     1 
ATOM 2003 O O     . LYS B 2 77  ? 147.006 159.137 208.671 1.00 102.49 ? 77  LYS B O     1 
ATOM 2004 C CB    . LYS B 2 77  ? 149.437 156.945 209.152 1.00 97.74  ? 77  LYS B CB    1 
ATOM 2005 C CG    . LYS B 2 77  ? 149.594 156.269 210.496 1.00 93.74  ? 77  LYS B CG    1 
ATOM 2006 C CD    . LYS B 2 77  ? 150.856 156.743 211.198 1.00 97.87  ? 77  LYS B CD    1 
ATOM 2007 C CE    . LYS B 2 77  ? 150.886 158.255 211.346 1.00 102.31 ? 77  LYS B CE    1 
ATOM 2008 N NZ    . LYS B 2 77  ? 149.604 158.798 211.867 1.00 100.61 ? 77  LYS B NZ    1 
ATOM 2009 N N     . GLN B 2 78  ? 148.141 158.598 206.807 1.00 98.55  ? 78  GLN B N     1 
ATOM 2010 C CA    . GLN B 2 78  ? 148.062 159.954 206.279 1.00 98.76  ? 78  GLN B CA    1 
ATOM 2011 C C     . GLN B 2 78  ? 146.621 160.399 206.070 1.00 104.49 ? 78  GLN B C     1 
ATOM 2012 O O     . GLN B 2 78  ? 146.270 161.538 206.395 1.00 108.37 ? 78  GLN B O     1 
ATOM 2013 C CB    . GLN B 2 78  ? 148.850 160.050 204.978 1.00 102.24 ? 78  GLN B CB    1 
ATOM 2014 C CG    . GLN B 2 78  ? 150.292 159.620 205.125 1.00 102.19 ? 78  GLN B CG    1 
ATOM 2015 C CD    . GLN B 2 78  ? 151.109 160.574 205.970 1.00 104.40 ? 78  GLN B CD    1 
ATOM 2016 O OE1   . GLN B 2 78  ? 150.703 161.709 206.222 1.00 104.47 ? 78  GLN B OE1   1 
ATOM 2017 N NE2   . GLN B 2 78  ? 152.267 160.112 206.421 1.00 110.01 ? 78  GLN B NE2   1 
ATOM 2018 N N     . GLU B 2 79  ? 145.771 159.519 205.537 1.00 115.63 ? 79  GLU B N     1 
ATOM 2019 C CA    . GLU B 2 79  ? 144.373 159.886 205.321 1.00 115.43 ? 79  GLU B CA    1 
ATOM 2020 C C     . GLU B 2 79  ? 143.656 160.203 206.628 1.00 115.04 ? 79  GLU B C     1 
ATOM 2021 O O     . GLU B 2 79  ? 142.856 161.144 206.685 1.00 114.97 ? 79  GLU B O     1 
ATOM 2022 C CB    . GLU B 2 79  ? 143.638 158.787 204.549 1.00 115.15 ? 79  GLU B CB    1 
ATOM 2023 C CG    . GLU B 2 79  ? 144.509 157.880 203.688 1.00 119.93 ? 79  GLU B CG    1 
ATOM 2024 C CD    . GLU B 2 79  ? 145.413 158.673 202.747 1.00 123.35 ? 79  GLU B CD    1 
ATOM 2025 O OE1   . GLU B 2 79  ? 144.885 159.553 202.035 1.00 122.14 ? 79  GLU B OE1   1 
ATOM 2026 O OE2   . GLU B 2 79  ? 146.634 158.423 202.703 1.00 121.96 ? 79  GLU B OE2   1 
ATOM 2027 N N     . ARG B 2 80  ? 143.917 159.433 207.687 1.00 122.12 ? 80  ARG B N     1 
ATOM 2028 C CA    . ARG B 2 80  ? 143.217 159.688 208.943 1.00 123.79 ? 80  ARG B CA    1 
ATOM 2029 C C     . ARG B 2 80  ? 143.595 161.043 209.537 1.00 126.78 ? 80  ARG B C     1 
ATOM 2030 O O     . ARG B 2 80  ? 142.713 161.813 209.932 1.00 128.04 ? 80  ARG B O     1 
ATOM 2031 C CB    . ARG B 2 80  ? 143.476 158.561 209.942 1.00 122.44 ? 80  ARG B CB    1 
ATOM 2032 C CG    . ARG B 2 80  ? 143.333 157.163 209.370 1.00 120.81 ? 80  ARG B CG    1 
ATOM 2033 C CD    . ARG B 2 80  ? 143.092 156.168 210.491 1.00 123.11 ? 80  ARG B CD    1 
ATOM 2034 N NE    . ARG B 2 80  ? 143.623 154.843 210.199 1.00 125.92 ? 80  ARG B NE    1 
ATOM 2035 C CZ    . ARG B 2 80  ? 143.023 153.952 209.423 1.00 127.08 ? 80  ARG B CZ    1 
ATOM 2036 N NH1   . ARG B 2 80  ? 141.871 154.217 208.830 1.00 128.28 ? 80  ARG B NH1   1 
ATOM 2037 N NH2   . ARG B 2 80  ? 143.589 152.763 209.243 1.00 124.96 ? 80  ARG B NH2   1 
ATOM 2038 N N     . GLU B 2 81  ? 144.889 161.361 209.608 1.00 123.51 ? 81  GLU B N     1 
ATOM 2039 C CA    . GLU B 2 81  ? 145.309 162.674 210.089 1.00 119.76 ? 81  GLU B CA    1 
ATOM 2040 C C     . GLU B 2 81  ? 145.371 163.735 208.997 1.00 121.49 ? 81  GLU B C     1 
ATOM 2041 O O     . GLU B 2 81  ? 145.584 164.909 209.317 1.00 121.32 ? 81  GLU B O     1 
ATOM 2042 C CB    . GLU B 2 81  ? 146.674 162.606 210.797 1.00 118.16 ? 81  GLU B CB    1 
ATOM 2043 C CG    . GLU B 2 81  ? 146.722 161.881 212.153 1.00 120.32 ? 81  GLU B CG    1 
ATOM 2044 C CD    . GLU B 2 81  ? 146.217 160.449 212.143 1.00 123.96 ? 81  GLU B CD    1 
ATOM 2045 O OE1   . GLU B 2 81  ? 145.981 159.889 211.058 1.00 124.32 ? 81  GLU B OE1   1 
ATOM 2046 O OE2   . GLU B 2 81  ? 146.047 159.881 213.241 1.00 126.47 ? 81  GLU B OE2   1 
ATOM 2047 N N     . GLY B 2 82  ? 145.189 163.366 207.732 1.00 129.91 ? 82  GLY B N     1 
ATOM 2048 C CA    . GLY B 2 82  ? 145.121 164.366 206.684 1.00 129.58 ? 82  GLY B CA    1 
ATOM 2049 C C     . GLY B 2 82  ? 146.425 165.057 206.354 1.00 130.45 ? 82  GLY B C     1 
ATOM 2050 O O     . GLY B 2 82  ? 146.409 166.219 205.938 1.00 131.31 ? 82  GLY B O     1 
ATOM 2051 N N     . GLY B 2 83  ? 147.557 164.381 206.524 1.00 116.83 ? 83  GLY B N     1 
ATOM 2052 C CA    . GLY B 2 83  ? 148.850 164.951 206.195 1.00 114.87 ? 83  GLY B CA    1 
ATOM 2053 C C     . GLY B 2 83  ? 149.124 164.938 204.707 1.00 115.74 ? 83  GLY B C     1 
ATOM 2054 O O     . GLY B 2 83  ? 148.226 165.140 203.881 1.00 117.12 ? 83  GLY B O     1 
ATOM 2055 N N     . ILE B 2 84  ? 150.390 164.717 204.355 1.00 102.60 ? 84  ILE B N     1 
ATOM 2056 C CA    . ILE B 2 84  ? 150.750 164.509 202.959 1.00 98.67  ? 84  ILE B CA    1 
ATOM 2057 C C     . ILE B 2 84  ? 150.353 163.097 202.558 1.00 100.62 ? 84  ILE B C     1 
ATOM 2058 O O     . ILE B 2 84  ? 150.682 162.125 203.248 1.00 103.59 ? 84  ILE B O     1 
ATOM 2059 C CB    . ILE B 2 84  ? 152.251 164.750 202.744 1.00 94.01  ? 84  ILE B CB    1 
ATOM 2060 C CG1   . ILE B 2 84  ? 152.518 166.232 202.496 1.00 93.82  ? 84  ILE B CG1   1 
ATOM 2061 C CG2   . ILE B 2 84  ? 152.762 163.935 201.570 1.00 96.65  ? 84  ILE B CG2   1 
ATOM 2062 C CD1   . ILE B 2 84  ? 153.907 166.675 202.870 1.00 94.61  ? 84  ILE B CD1   1 
ATOM 2063 N N     . GLN B 2 85  ? 149.629 162.976 201.448 1.00 102.94 ? 85  GLN B N     1 
ATOM 2064 C CA    . GLN B 2 85  ? 149.135 161.680 201.005 1.00 102.92 ? 85  GLN B CA    1 
ATOM 2065 C C     . GLN B 2 85  ? 149.916 161.101 199.840 1.00 102.83 ? 85  GLN B C     1 
ATOM 2066 O O     . GLN B 2 85  ? 150.076 159.879 199.765 1.00 105.92 ? 85  GLN B O     1 
ATOM 2067 C CB    . GLN B 2 85  ? 147.659 161.786 200.611 1.00 103.85 ? 85  GLN B CB    1 
ATOM 2068 C CG    . GLN B 2 85  ? 146.745 162.156 201.762 1.00 102.76 ? 85  GLN B CG    1 
ATOM 2069 C CD    . GLN B 2 85  ? 146.500 163.646 201.849 1.00 105.00 ? 85  GLN B CD    1 
ATOM 2070 O OE1   . GLN B 2 85  ? 147.163 164.436 201.176 1.00 106.75 ? 85  GLN B OE1   1 
ATOM 2071 N NE2   . GLN B 2 85  ? 145.550 164.042 202.686 1.00 100.59 ? 85  GLN B NE2   1 
ATOM 2072 N N     . HIS B 2 86  ? 150.406 161.942 198.931 1.00 94.39  ? 86  HIS B N     1 
ATOM 2073 C CA    . HIS B 2 86  ? 151.120 161.471 197.745 1.00 93.12  ? 86  HIS B CA    1 
ATOM 2074 C C     . HIS B 2 86  ? 152.608 161.328 198.064 1.00 92.76  ? 86  HIS B C     1 
ATOM 2075 O O     . HIS B 2 86  ? 153.463 162.068 197.580 1.00 90.83  ? 86  HIS B O     1 
ATOM 2076 C CB    . HIS B 2 86  ? 150.886 162.416 196.574 1.00 94.84  ? 86  HIS B CB    1 
ATOM 2077 C CG    . HIS B 2 86  ? 149.440 162.672 196.280 1.00 97.97  ? 86  HIS B CG    1 
ATOM 2078 N ND1   . HIS B 2 86  ? 148.811 162.179 195.157 1.00 101.04 ? 86  HIS B ND1   1 
ATOM 2079 C CD2   . HIS B 2 86  ? 148.497 163.361 196.966 1.00 97.90  ? 86  HIS B CD2   1 
ATOM 2080 C CE1   . HIS B 2 86  ? 147.547 162.561 195.160 1.00 102.58 ? 86  HIS B CE1   1 
ATOM 2081 N NE2   . HIS B 2 86  ? 147.331 163.280 196.246 1.00 102.31 ? 86  HIS B NE2   1 
ATOM 2082 N N     . ILE B 2 87  ? 152.906 160.336 198.901 1.00 77.37  ? 87  ILE B N     1 
ATOM 2083 C CA    . ILE B 2 87  ? 154.286 160.080 199.283 1.00 76.54  ? 87  ILE B CA    1 
ATOM 2084 C C     . ILE B 2 87  ? 155.026 159.465 198.107 1.00 73.56  ? 87  ILE B C     1 
ATOM 2085 O O     . ILE B 2 87  ? 154.593 158.457 197.536 1.00 74.15  ? 87  ILE B O     1 
ATOM 2086 C CB    . ILE B 2 87  ? 154.357 159.166 200.515 1.00 75.71  ? 87  ILE B CB    1 
ATOM 2087 C CG1   . ILE B 2 87  ? 153.913 159.910 201.771 1.00 73.45  ? 87  ILE B CG1   1 
ATOM 2088 C CG2   . ILE B 2 87  ? 155.766 158.652 200.700 1.00 78.62  ? 87  ILE B CG2   1 
ATOM 2089 C CD1   . ILE B 2 87  ? 152.443 159.809 202.049 1.00 82.38  ? 87  ILE B CD1   1 
ATOM 2090 N N     . SER B 2 88  ? 156.154 160.068 197.742 1.00 67.63  ? 88  SER B N     1 
ATOM 2091 C CA    . SER B 2 88  ? 156.981 159.565 196.650 1.00 69.11  ? 88  SER B CA    1 
ATOM 2092 C C     . SER B 2 88  ? 157.820 158.411 197.185 1.00 70.55  ? 88  SER B C     1 
ATOM 2093 O O     . SER B 2 88  ? 159.004 158.546 197.497 1.00 77.90  ? 88  SER B O     1 
ATOM 2094 C CB    . SER B 2 88  ? 157.848 160.677 196.081 1.00 74.54  ? 88  SER B CB    1 
ATOM 2095 O OG    . SER B 2 88  ? 159.000 160.869 196.878 1.00 79.86  ? 88  SER B OG    1 
ATOM 2096 N N     . TRP B 2 89  ? 157.181 157.245 197.290 1.00 76.39  ? 89  TRP B N     1 
ATOM 2097 C CA    . TRP B 2 89  ? 157.858 156.072 197.830 1.00 73.61  ? 89  TRP B CA    1 
ATOM 2098 C C     . TRP B 2 89  ? 159.001 155.605 196.949 1.00 76.12  ? 89  TRP B C     1 
ATOM 2099 O O     . TRP B 2 89  ? 159.857 154.849 197.416 1.00 78.13  ? 89  TRP B O     1 
ATOM 2100 C CB    . TRP B 2 89  ? 156.860 154.937 198.040 1.00 74.33  ? 89  TRP B CB    1 
ATOM 2101 C CG    . TRP B 2 89  ? 155.996 155.170 199.222 1.00 73.00  ? 89  TRP B CG    1 
ATOM 2102 C CD1   . TRP B 2 89  ? 154.729 155.665 199.227 1.00 78.83  ? 89  TRP B CD1   1 
ATOM 2103 C CD2   . TRP B 2 89  ? 156.346 154.943 200.587 1.00 70.82  ? 89  TRP B CD2   1 
ATOM 2104 N NE1   . TRP B 2 89  ? 154.262 155.751 200.514 1.00 73.15  ? 89  TRP B NE1   1 
ATOM 2105 C CE2   . TRP B 2 89  ? 155.240 155.315 201.368 1.00 71.36  ? 89  TRP B CE2   1 
ATOM 2106 C CE3   . TRP B 2 89  ? 157.490 154.458 201.224 1.00 78.17  ? 89  TRP B CE3   1 
ATOM 2107 C CZ2   . TRP B 2 89  ? 155.241 155.218 202.752 1.00 79.32  ? 89  TRP B CZ2   1 
ATOM 2108 C CZ3   . TRP B 2 89  ? 157.489 154.361 202.596 1.00 78.45  ? 89  TRP B CZ3   1 
ATOM 2109 C CH2   . TRP B 2 89  ? 156.373 154.739 203.347 1.00 85.22  ? 89  TRP B CH2   1 
ATOM 2110 N N     . SER B 2 90  ? 159.029 156.021 195.683 1.00 72.11  ? 90  SER B N     1 
ATOM 2111 C CA    . SER B 2 90  ? 160.188 155.737 194.848 1.00 70.99  ? 90  SER B CA    1 
ATOM 2112 C C     . SER B 2 90  ? 161.431 156.415 195.402 1.00 81.08  ? 90  SER B C     1 
ATOM 2113 O O     . SER B 2 90  ? 162.507 155.811 195.454 1.00 88.20  ? 90  SER B O     1 
ATOM 2114 C CB    . SER B 2 90  ? 159.925 156.190 193.415 1.00 83.12  ? 90  SER B CB    1 
ATOM 2115 O OG    . SER B 2 90  ? 159.516 157.546 193.383 1.00 85.83  ? 90  SER B OG    1 
ATOM 2116 N N     . TYR B 2 91  ? 161.297 157.671 195.829 1.00 80.06  ? 91  TYR B N     1 
ATOM 2117 C CA    . TYR B 2 91  ? 162.433 158.395 196.387 1.00 73.65  ? 91  TYR B CA    1 
ATOM 2118 C C     . TYR B 2 91  ? 162.796 157.868 197.768 1.00 60.86  ? 91  TYR B C     1 
ATOM 2119 O O     . TYR B 2 91  ? 163.975 157.660 198.073 1.00 56.07  ? 91  TYR B O     1 
ATOM 2120 C CB    . TYR B 2 91  ? 162.115 159.888 196.458 1.00 76.01  ? 91  TYR B CB    1 
ATOM 2121 C CG    . TYR B 2 91  ? 162.713 160.576 197.662 1.00 69.02  ? 91  TYR B CG    1 
ATOM 2122 C CD1   . TYR B 2 91  ? 164.030 161.001 197.656 1.00 74.61  ? 91  TYR B CD1   1 
ATOM 2123 C CD2   . TYR B 2 91  ? 161.967 160.792 198.806 1.00 68.44  ? 91  TYR B CD2   1 
ATOM 2124 C CE1   . TYR B 2 91  ? 164.582 161.627 198.752 1.00 65.07  ? 91  TYR B CE1   1 
ATOM 2125 C CE2   . TYR B 2 91  ? 162.518 161.411 199.905 1.00 74.47  ? 91  TYR B CE2   1 
ATOM 2126 C CZ    . TYR B 2 91  ? 163.821 161.828 199.871 1.00 68.96  ? 91  TYR B CZ    1 
ATOM 2127 O OH    . TYR B 2 91  ? 164.365 162.449 200.967 1.00 74.60  ? 91  TYR B OH    1 
ATOM 2128 N N     . VAL B 2 92  ? 161.789 157.645 198.614 1.00 65.36  ? 92  VAL B N     1 
ATOM 2129 C CA    . VAL B 2 92  ? 162.043 157.291 200.008 1.00 67.98  ? 92  VAL B CA    1 
ATOM 2130 C C     . VAL B 2 92  ? 162.837 155.997 200.090 1.00 64.45  ? 92  VAL B C     1 
ATOM 2131 O O     . VAL B 2 92  ? 163.803 155.886 200.853 1.00 71.60  ? 92  VAL B O     1 
ATOM 2132 C CB    . VAL B 2 92  ? 160.719 157.192 200.785 1.00 67.74  ? 92  VAL B CB    1 
ATOM 2133 C CG1   . VAL B 2 92  ? 160.905 156.370 202.043 1.00 64.14  ? 92  VAL B CG1   1 
ATOM 2134 C CG2   . VAL B 2 92  ? 160.204 158.575 201.125 1.00 68.40  ? 92  VAL B CG2   1 
ATOM 2135 N N     . TRP B 2 93  ? 162.452 155.003 199.300 1.00 74.26  ? 93  TRP B N     1 
ATOM 2136 C CA    . TRP B 2 93  ? 163.206 153.761 199.279 1.00 73.61  ? 93  TRP B CA    1 
ATOM 2137 C C     . TRP B 2 93  ? 164.457 153.859 198.423 1.00 82.98  ? 93  TRP B C     1 
ATOM 2138 O O     . TRP B 2 93  ? 165.286 152.944 198.459 1.00 85.00  ? 93  TRP B O     1 
ATOM 2139 C CB    . TRP B 2 93  ? 162.321 152.621 198.782 1.00 76.82  ? 93  TRP B CB    1 
ATOM 2140 C CG    . TRP B 2 93  ? 161.230 152.257 199.745 1.00 82.62  ? 93  TRP B CG    1 
ATOM 2141 C CD1   . TRP B 2 93  ? 159.902 152.159 199.466 1.00 80.11  ? 93  TRP B CD1   1 
ATOM 2142 C CD2   . TRP B 2 93  ? 161.367 151.958 201.143 1.00 79.41  ? 93  TRP B CD2   1 
ATOM 2143 N NE1   . TRP B 2 93  ? 159.203 151.814 200.595 1.00 81.25  ? 93  TRP B NE1   1 
ATOM 2144 C CE2   . TRP B 2 93  ? 160.080 151.683 201.638 1.00 78.77  ? 93  TRP B CE2   1 
ATOM 2145 C CE3   . TRP B 2 93  ? 162.453 151.889 202.021 1.00 77.41  ? 93  TRP B CE3   1 
ATOM 2146 C CZ2   . TRP B 2 93  ? 159.849 151.349 202.967 1.00 78.09  ? 93  TRP B CZ2   1 
ATOM 2147 C CZ3   . TRP B 2 93  ? 162.220 151.558 203.338 1.00 80.81  ? 93  TRP B CZ3   1 
ATOM 2148 C CH2   . TRP B 2 93  ? 160.929 151.292 203.799 1.00 82.64  ? 93  TRP B CH2   1 
ATOM 2149 N N     . ARG B 2 94  ? 164.609 154.936 197.650 1.00 85.20  ? 94  ARG B N     1 
ATOM 2150 C CA    . ARG B 2 94  ? 165.829 155.116 196.872 1.00 81.73  ? 94  ARG B CA    1 
ATOM 2151 C C     . ARG B 2 94  ? 166.980 155.579 197.754 1.00 76.67  ? 94  ARG B C     1 
ATOM 2152 O O     . ARG B 2 94  ? 168.123 155.149 197.564 1.00 79.17  ? 94  ARG B O     1 
ATOM 2153 C CB    . ARG B 2 94  ? 165.589 156.107 195.732 1.00 80.47  ? 94  ARG B CB    1 
ATOM 2154 C CG    . ARG B 2 94  ? 166.854 156.672 195.113 1.00 81.78  ? 94  ARG B CG    1 
ATOM 2155 C CD    . ARG B 2 94  ? 166.582 157.955 194.350 1.00 85.18  ? 94  ARG B CD    1 
ATOM 2156 N NE    . ARG B 2 94  ? 165.256 157.971 193.745 1.00 86.14  ? 94  ARG B NE    1 
ATOM 2157 C CZ    . ARG B 2 94  ? 164.516 159.061 193.593 1.00 82.44  ? 94  ARG B CZ    1 
ATOM 2158 N NH1   . ARG B 2 94  ? 164.939 160.246 194.003 1.00 83.09  ? 94  ARG B NH1   1 
ATOM 2159 N NH2   . ARG B 2 94  ? 163.323 158.961 193.016 1.00 72.10  ? 94  ARG B NH2   1 
ATOM 2160 N N     . THR B 2 95  ? 166.700 156.437 198.733 1.00 66.05  ? 95  THR B N     1 
ATOM 2161 C CA    . THR B 2 95  ? 167.761 157.030 199.537 1.00 68.87  ? 95  THR B CA    1 
ATOM 2162 C C     . THR B 2 95  ? 167.941 156.352 200.887 1.00 68.75  ? 95  THR B C     1 
ATOM 2163 O O     . THR B 2 95  ? 169.070 156.255 201.378 1.00 79.91  ? 95  THR B O     1 
ATOM 2164 C CB    . THR B 2 95  ? 167.486 158.515 199.757 1.00 70.23  ? 95  THR B CB    1 
ATOM 2165 O OG1   . THR B 2 95  ? 166.610 158.680 200.876 1.00 71.83  ? 95  THR B OG1   1 
ATOM 2166 C CG2   . THR B 2 95  ? 166.842 159.108 198.530 1.00 69.56  ? 95  THR B CG2   1 
ATOM 2167 N N     . TYR B 2 96  ? 166.861 155.892 201.505 1.00 64.69  ? 96  TYR B N     1 
ATOM 2168 C CA    . TYR B 2 96  ? 166.937 155.327 202.843 1.00 58.38  ? 96  TYR B CA    1 
ATOM 2169 C C     . TYR B 2 96  ? 166.979 153.808 202.794 1.00 55.67  ? 96  TYR B C     1 
ATOM 2170 O O     . TYR B 2 96  ? 166.416 153.177 201.899 1.00 69.63  ? 96  TYR B O     1 
ATOM 2171 C CB    . TYR B 2 96  ? 165.754 155.787 203.688 1.00 58.59  ? 96  TYR B CB    1 
ATOM 2172 C CG    . TYR B 2 96  ? 165.728 157.278 203.901 1.00 66.26  ? 96  TYR B CG    1 
ATOM 2173 C CD1   . TYR B 2 96  ? 166.703 157.905 204.657 1.00 68.49  ? 96  TYR B CD1   1 
ATOM 2174 C CD2   . TYR B 2 96  ? 164.737 158.060 203.336 1.00 73.64  ? 96  TYR B CD2   1 
ATOM 2175 C CE1   . TYR B 2 96  ? 166.686 159.267 204.850 1.00 68.34  ? 96  TYR B CE1   1 
ATOM 2176 C CE2   . TYR B 2 96  ? 164.712 159.421 203.522 1.00 67.85  ? 96  TYR B CE2   1 
ATOM 2177 C CZ    . TYR B 2 96  ? 165.689 160.020 204.279 1.00 65.81  ? 96  TYR B CZ    1 
ATOM 2178 O OH    . TYR B 2 96  ? 165.662 161.381 204.465 1.00 67.86  ? 96  TYR B OH    1 
ATOM 2179 N N     . HIS B 2 97  ? 167.664 153.229 203.767 1.00 75.25  ? 97  HIS B N     1 
ATOM 2180 C CA    . HIS B 2 97  ? 167.764 151.790 203.931 1.00 82.48  ? 97  HIS B CA    1 
ATOM 2181 C C     . HIS B 2 97  ? 166.905 151.351 205.108 1.00 87.59  ? 97  HIS B C     1 
ATOM 2182 O O     . HIS B 2 97  ? 166.258 152.159 205.779 1.00 95.11  ? 97  HIS B O     1 
ATOM 2183 C CB    . HIS B 2 97  ? 169.217 151.365 204.152 1.00 90.12  ? 97  HIS B CB    1 
ATOM 2184 C CG    . HIS B 2 97  ? 169.895 150.843 202.927 1.00 88.72  ? 97  HIS B CG    1 
ATOM 2185 N ND1   . HIS B 2 97  ? 169.584 149.624 202.367 1.00 90.66  ? 97  HIS B ND1   1 
ATOM 2186 C CD2   . HIS B 2 97  ? 170.895 151.358 202.175 1.00 86.08  ? 97  HIS B CD2   1 
ATOM 2187 C CE1   . HIS B 2 97  ? 170.346 149.421 201.308 1.00 91.69  ? 97  HIS B CE1   1 
ATOM 2188 N NE2   . HIS B 2 97  ? 171.154 150.457 201.172 1.00 90.55  ? 97  HIS B NE2   1 
ATOM 2189 N N     . LEU B 2 98  ? 166.912 150.050 205.360 1.00 86.39  ? 98  LEU B N     1 
ATOM 2190 C CA    . LEU B 2 98  ? 166.310 149.472 206.549 1.00 91.61  ? 98  LEU B CA    1 
ATOM 2191 C C     . LEU B 2 98  ? 167.384 148.682 207.278 1.00 94.77  ? 98  LEU B C     1 
ATOM 2192 O O     . LEU B 2 98  ? 168.074 147.860 206.671 1.00 102.01 ? 98  LEU B O     1 
ATOM 2193 C CB    . LEU B 2 98  ? 165.132 148.567 206.187 1.00 92.32  ? 98  LEU B CB    1 
ATOM 2194 C CG    . LEU B 2 98  ? 163.765 149.241 206.048 1.00 82.56  ? 98  LEU B CG    1 
ATOM 2195 C CD1   . LEU B 2 98  ? 162.669 148.202 205.961 1.00 82.66  ? 98  LEU B CD1   1 
ATOM 2196 C CD2   . LEU B 2 98  ? 163.507 150.188 207.196 1.00 85.39  ? 98  LEU B CD2   1 
ATOM 2197 N N     . THR B 2 99  ? 167.539 148.934 208.574 1.00 97.17  ? 99  THR B N     1 
ATOM 2198 C CA    . THR B 2 99  ? 168.616 148.295 209.313 1.00 96.91  ? 99  THR B CA    1 
ATOM 2199 C C     . THR B 2 99  ? 168.081 147.715 210.612 1.00 94.70  ? 99  THR B C     1 
ATOM 2200 O O     . THR B 2 99  ? 167.181 148.285 211.234 1.00 92.79  ? 99  THR B O     1 
ATOM 2201 C CB    . THR B 2 99  ? 169.758 149.274 209.607 1.00 99.36  ? 99  THR B CB    1 
ATOM 2202 O OG1   . THR B 2 99  ? 170.668 148.683 210.542 1.00 100.50 ? 99  THR B OG1   1 
ATOM 2203 C CG2   . THR B 2 99  ? 169.217 150.566 210.186 1.00 97.96  ? 99  THR B CG2   1 
ATOM 2204 N N     . SER B 2 100 ? 168.641 146.574 211.004 1.00 101.97 ? 100 SER B N     1 
ATOM 2205 C CA    . SER B 2 100 ? 168.295 145.923 212.258 1.00 100.72 ? 100 SER B CA    1 
ATOM 2206 C C     . SER B 2 100 ? 169.544 145.267 212.820 1.00 103.39 ? 100 SER B C     1 
ATOM 2207 O O     . SER B 2 100 ? 170.226 144.524 212.108 1.00 102.69 ? 100 SER B O     1 
ATOM 2208 C CB    . SER B 2 100 ? 167.194 144.881 212.061 1.00 101.87 ? 100 SER B CB    1 
ATOM 2209 O OG    . SER B 2 100 ? 166.727 144.399 213.309 1.00 101.31 ? 100 SER B OG    1 
ATOM 2210 N N     . ALA B 2 101 ? 169.835 145.547 214.091 1.00 115.36 ? 101 ALA B N     1 
ATOM 2211 C CA    . ALA B 2 101 ? 171.022 145.029 214.771 1.00 117.15 ? 101 ALA B CA    1 
ATOM 2212 C C     . ALA B 2 101 ? 172.304 145.409 214.037 1.00 116.33 ? 101 ALA B C     1 
ATOM 2213 O O     . ALA B 2 101 ? 173.284 144.660 214.047 1.00 116.58 ? 101 ALA B O     1 
ATOM 2214 C CB    . ALA B 2 101 ? 170.941 143.511 214.957 1.00 115.97 ? 101 ALA B CB    1 
ATOM 2215 N N     . GLY B 2 102 ? 172.308 146.575 213.395 1.00 110.83 ? 102 GLY B N     1 
ATOM 2216 C CA    . GLY B 2 102 ? 173.465 147.036 212.661 1.00 109.61 ? 102 GLY B CA    1 
ATOM 2217 C C     . GLY B 2 102 ? 173.638 146.439 211.283 1.00 111.21 ? 102 GLY B C     1 
ATOM 2218 O O     . GLY B 2 102 ? 174.629 146.755 210.612 1.00 111.54 ? 102 GLY B O     1 
ATOM 2219 N N     . GLU B 2 103 ? 172.717 145.591 210.836 1.00 115.26 ? 103 GLU B N     1 
ATOM 2220 C CA    . GLU B 2 103 ? 172.778 144.981 209.514 1.00 115.41 ? 103 GLU B CA    1 
ATOM 2221 C C     . GLU B 2 103 ? 171.699 145.606 208.642 1.00 114.44 ? 103 GLU B C     1 
ATOM 2222 O O     . GLU B 2 103 ? 170.515 145.571 208.994 1.00 116.12 ? 103 GLU B O     1 
ATOM 2223 C CB    . GLU B 2 103 ? 172.597 143.466 209.598 1.00 117.94 ? 103 GLU B CB    1 
ATOM 2224 C CG    . GLU B 2 103 ? 172.984 142.721 208.326 1.00 116.80 ? 103 GLU B CG    1 
ATOM 2225 C CD    . GLU B 2 103 ? 172.714 141.230 208.412 1.00 117.16 ? 103 GLU B CD    1 
ATOM 2226 O OE1   . GLU B 2 103 ? 172.946 140.643 209.489 1.00 117.45 ? 103 GLU B OE1   1 
ATOM 2227 O OE2   . GLU B 2 103 ? 172.275 140.644 207.401 1.00 113.05 ? 103 GLU B OE2   1 
ATOM 2228 N N     . LYS B 2 104 ? 172.108 146.176 207.514 1.00 102.97 ? 104 LYS B N     1 
ATOM 2229 C CA    . LYS B 2 104 ? 171.166 146.834 206.618 1.00 103.44 ? 104 LYS B CA    1 
ATOM 2230 C C     . LYS B 2 104 ? 170.368 145.794 205.844 1.00 112.71 ? 104 LYS B C     1 
ATOM 2231 O O     . LYS B 2 104 ? 170.938 144.852 205.284 1.00 111.43 ? 104 LYS B O     1 
ATOM 2232 C CB    . LYS B 2 104 ? 171.906 147.764 205.661 1.00 99.49  ? 104 LYS B CB    1 
ATOM 2233 C CG    . LYS B 2 104 ? 172.112 149.169 206.193 1.00 102.95 ? 104 LYS B CG    1 
ATOM 2234 C CD    . LYS B 2 104 ? 172.947 150.000 205.234 1.00 106.11 ? 104 LYS B CD    1 
ATOM 2235 C CE    . LYS B 2 104 ? 174.393 149.530 205.215 1.00 110.82 ? 104 LYS B CE    1 
ATOM 2236 N NZ    . LYS B 2 104 ? 175.270 150.453 204.445 1.00 106.89 ? 104 LYS B NZ    1 
ATOM 2237 N N     . LEU B 2 105 ? 169.050 145.968 205.812 1.00 111.21 ? 105 LEU B N     1 
ATOM 2238 C CA    . LEU B 2 105 ? 168.159 145.086 205.063 1.00 97.97  ? 105 LEU B CA    1 
ATOM 2239 C C     . LEU B 2 105 ? 168.199 145.494 203.598 1.00 102.22 ? 105 LEU B C     1 
ATOM 2240 O O     . LEU B 2 105 ? 167.438 146.359 203.161 1.00 101.95 ? 105 LEU B O     1 
ATOM 2241 C CB    . LEU B 2 105 ? 166.744 145.179 205.617 1.00 95.53  ? 105 LEU B CB    1 
ATOM 2242 C CG    . LEU B 2 105 ? 166.583 144.859 207.101 1.00 97.55  ? 105 LEU B CG    1 
ATOM 2243 C CD1   . LEU B 2 105 ? 165.120 144.894 207.496 1.00 102.75 ? 105 LEU B CD1   1 
ATOM 2244 C CD2   . LEU B 2 105 ? 167.195 143.517 207.424 1.00 98.47  ? 105 LEU B CD2   1 
ATOM 2245 N N     . THR B 2 106 ? 169.089 144.877 202.829 1.00 111.89 ? 106 THR B N     1 
ATOM 2246 C CA    . THR B 2 106 ? 169.259 145.216 201.422 1.00 111.25 ? 106 THR B CA    1 
ATOM 2247 C C     . THR B 2 106 ? 168.495 144.296 200.485 1.00 112.16 ? 106 THR B C     1 
ATOM 2248 O O     . THR B 2 106 ? 167.828 144.777 199.566 1.00 111.13 ? 106 THR B O     1 
ATOM 2249 C CB    . THR B 2 106 ? 170.744 145.190 201.046 1.00 109.36 ? 106 THR B CB    1 
ATOM 2250 O OG1   . THR B 2 106 ? 171.288 143.894 201.322 1.00 112.91 ? 106 THR B OG1   1 
ATOM 2251 C CG2   . THR B 2 106 ? 171.505 146.222 201.848 1.00 111.87 ? 106 THR B CG2   1 
ATOM 2252 N N     . GLU B 2 107 ? 168.567 142.986 200.699 1.00 115.12 ? 107 GLU B N     1 
ATOM 2253 C CA    . GLU B 2 107 ? 167.896 142.016 199.838 1.00 113.98 ? 107 GLU B CA    1 
ATOM 2254 C C     . GLU B 2 107 ? 166.393 142.124 200.046 1.00 118.97 ? 107 GLU B C     1 
ATOM 2255 O O     . GLU B 2 107 ? 165.863 141.690 201.070 1.00 120.93 ? 107 GLU B O     1 
ATOM 2256 C CB    . GLU B 2 107 ? 168.387 140.608 200.148 1.00 115.99 ? 107 GLU B CB    1 
ATOM 2257 C CG    . GLU B 2 107 ? 169.765 140.294 199.615 1.00 115.38 ? 107 GLU B CG    1 
ATOM 2258 C CD    . GLU B 2 107 ? 170.062 138.812 199.646 1.00 120.71 ? 107 GLU B CD    1 
ATOM 2259 O OE1   . GLU B 2 107 ? 169.679 138.107 198.689 1.00 121.89 ? 107 GLU B OE1   1 
ATOM 2260 O OE2   . GLU B 2 107 ? 170.670 138.349 200.633 1.00 120.85 ? 107 GLU B OE2   1 
ATOM 2261 N N     . ASP B 2 108 ? 165.697 142.715 199.073 1.00 111.66 ? 108 ASP B N     1 
ATOM 2262 C CA    . ASP B 2 108 ? 164.244 142.805 199.163 1.00 108.19 ? 108 ASP B CA    1 
ATOM 2263 C C     . ASP B 2 108 ? 163.595 141.430 199.088 1.00 106.89 ? 108 ASP B C     1 
ATOM 2264 O O     . ASP B 2 108 ? 162.490 141.234 199.603 1.00 109.78 ? 108 ASP B O     1 
ATOM 2265 C CB    . ASP B 2 108 ? 163.704 143.710 198.057 1.00 103.57 ? 108 ASP B CB    1 
ATOM 2266 C CG    . ASP B 2 108 ? 163.741 145.176 198.434 1.00 105.04 ? 108 ASP B CG    1 
ATOM 2267 O OD1   . ASP B 2 108 ? 164.146 145.488 199.572 1.00 105.40 ? 108 ASP B OD1   1 
ATOM 2268 O OD2   . ASP B 2 108 ? 163.366 146.018 197.591 1.00 100.48 ? 108 ASP B OD2   1 
ATOM 2269 N N     . ARG B 2 109 ? 164.265 140.469 198.452 1.00 117.92 ? 109 ARG B N     1 
ATOM 2270 C CA    . ARG B 2 109 ? 163.688 139.140 198.284 1.00 120.18 ? 109 ARG B CA    1 
ATOM 2271 C C     . ARG B 2 109 ? 163.817 138.300 199.550 1.00 119.65 ? 109 ARG B C     1 
ATOM 2272 O O     . ARG B 2 109 ? 162.963 137.449 199.822 1.00 118.62 ? 109 ARG B O     1 
ATOM 2273 C CB    . ARG B 2 109 ? 164.350 138.440 197.100 1.00 118.34 ? 109 ARG B CB    1 
ATOM 2274 C CG    . ARG B 2 109 ? 163.938 136.995 196.909 1.00 119.06 ? 109 ARG B CG    1 
ATOM 2275 C CD    . ARG B 2 109 ? 164.604 136.246 195.735 1.00 118.66 ? 109 ARG B CD    1 
ATOM 2276 N NE    . ARG B 2 109 ? 164.396 136.797 194.394 1.00 120.23 ? 109 ARG B NE    1 
ATOM 2277 C CZ    . ARG B 2 109 ? 164.924 137.915 193.907 1.00 122.54 ? 109 ARG B CZ    1 
ATOM 2278 N NH1   . ARG B 2 109 ? 165.852 138.590 194.562 1.00 121.91 ? 109 ARG B NH1   1 
ATOM 2279 N NH2   . ARG B 2 109 ? 164.552 138.335 192.700 1.00 121.81 ? 109 ARG B NH2   1 
ATOM 2280 N N     . LYS B 2 110 ? 164.871 138.513 200.333 1.00 105.86 ? 110 LYS B N     1 
ATOM 2281 C CA    . LYS B 2 110 ? 165.080 137.700 201.523 1.00 103.31 ? 110 LYS B CA    1 
ATOM 2282 C C     . LYS B 2 110 ? 163.992 137.961 202.560 1.00 101.78 ? 110 LYS B C     1 
ATOM 2283 O O     . LYS B 2 110 ? 163.413 139.049 202.631 1.00 101.61 ? 110 LYS B O     1 
ATOM 2284 C CB    . LYS B 2 110 ? 166.458 137.967 202.125 1.00 104.04 ? 110 LYS B CB    1 
ATOM 2285 C CG    . LYS B 2 110 ? 166.955 136.845 203.028 1.00 105.05 ? 110 LYS B CG    1 
ATOM 2286 C CD    . LYS B 2 110 ? 168.451 136.649 202.886 1.00 103.80 ? 110 LYS B CD    1 
ATOM 2287 C CE    . LYS B 2 110 ? 169.216 137.695 203.661 1.00 105.46 ? 110 LYS B CE    1 
ATOM 2288 N NZ    . LYS B 2 110 ? 170.678 137.594 203.441 1.00 107.06 ? 110 LYS B NZ    1 
ATOM 2289 N N     . LYS B 2 111 ? 163.711 136.935 203.360 1.00 95.67  ? 111 LYS B N     1 
ATOM 2290 C CA    . LYS B 2 111 ? 162.637 136.977 204.341 1.00 96.51  ? 111 LYS B CA    1 
ATOM 2291 C C     . LYS B 2 111 ? 163.169 137.351 205.726 1.00 99.74  ? 111 LYS B C     1 
ATOM 2292 O O     . LYS B 2 111 ? 164.292 137.000 206.100 1.00 98.79  ? 111 LYS B O     1 
ATOM 2293 C CB    . LYS B 2 111 ? 161.924 135.623 204.360 1.00 97.37  ? 111 LYS B CB    1 
ATOM 2294 C CG    . LYS B 2 111 ? 161.283 135.217 205.667 1.00 101.10 ? 111 LYS B CG    1 
ATOM 2295 C CD    . LYS B 2 111 ? 160.994 133.730 205.693 1.00 99.65  ? 111 LYS B CD    1 
ATOM 2296 C CE    . LYS B 2 111 ? 160.353 133.252 204.422 1.00 99.77  ? 111 LYS B CE    1 
ATOM 2297 N NZ    . LYS B 2 111 ? 160.020 131.811 204.509 1.00 100.26 ? 111 LYS B NZ    1 
ATOM 2298 N N     . LEU B 2 112 ? 162.329 138.045 206.503 1.00 94.68  ? 112 LEU B N     1 
ATOM 2299 C CA    . LEU B 2 112 ? 162.811 138.709 207.710 1.00 88.59  ? 112 LEU B CA    1 
ATOM 2300 C C     . LEU B 2 112 ? 163.355 137.732 208.744 1.00 91.11  ? 112 LEU B C     1 
ATOM 2301 O O     . LEU B 2 112 ? 164.183 138.121 209.574 1.00 96.84  ? 112 LEU B O     1 
ATOM 2302 C CB    . LEU B 2 112 ? 161.700 139.550 208.334 1.00 84.81  ? 112 LEU B CB    1 
ATOM 2303 C CG    . LEU B 2 112 ? 161.018 140.563 207.417 1.00 86.04  ? 112 LEU B CG    1 
ATOM 2304 C CD1   . LEU B 2 112 ? 159.966 141.345 208.164 1.00 86.47  ? 112 LEU B CD1   1 
ATOM 2305 C CD2   . LEU B 2 112 ? 162.028 141.508 206.824 1.00 86.96  ? 112 LEU B CD2   1 
ATOM 2306 N N     . ARG B 2 113 ? 162.903 136.475 208.733 1.00 108.58 ? 113 ARG B N     1 
ATOM 2307 C CA    . ARG B 2 113 ? 163.359 135.551 209.770 1.00 114.66 ? 113 ARG B CA    1 
ATOM 2308 C C     . ARG B 2 113 ? 164.850 135.259 209.627 1.00 114.20 ? 113 ARG B C     1 
ATOM 2309 O O     . ARG B 2 113 ? 165.561 135.128 210.630 1.00 110.21 ? 113 ARG B O     1 
ATOM 2310 C CB    . ARG B 2 113 ? 162.533 134.256 209.759 1.00 112.26 ? 113 ARG B CB    1 
ATOM 2311 C CG    . ARG B 2 113 ? 162.832 133.290 208.624 1.00 111.75 ? 113 ARG B CG    1 
ATOM 2312 C CD    . ARG B 2 113 ? 161.955 132.031 208.692 1.00 109.33 ? 113 ARG B CD    1 
ATOM 2313 N NE    . ARG B 2 113 ? 161.898 131.331 207.413 1.00 111.48 ? 113 ARG B NE    1 
ATOM 2314 C CZ    . ARG B 2 113 ? 161.919 130.016 207.258 1.00 112.43 ? 113 ARG B CZ    1 
ATOM 2315 N NH1   . ARG B 2 113 ? 162.006 129.203 208.291 1.00 112.87 ? 113 ARG B NH1   1 
ATOM 2316 N NH2   . ARG B 2 113 ? 161.861 129.507 206.032 1.00 109.61 ? 113 ARG B NH2   1 
ATOM 2317 N N     . ASP B 2 114 ? 165.348 135.179 208.393 1.00 120.07 ? 114 ASP B N     1 
ATOM 2318 C CA    . ASP B 2 114 ? 166.774 134.951 208.192 1.00 120.91 ? 114 ASP B CA    1 
ATOM 2319 C C     . ASP B 2 114 ? 167.563 136.209 208.539 1.00 126.42 ? 114 ASP B C     1 
ATOM 2320 O O     . ASP B 2 114 ? 168.660 136.119 209.102 1.00 130.50 ? 114 ASP B O     1 
ATOM 2321 C CB    . ASP B 2 114 ? 167.005 134.491 206.745 1.00 122.94 ? 114 ASP B CB    1 
ATOM 2322 C CG    . ASP B 2 114 ? 168.458 134.591 206.282 1.00 127.81 ? 114 ASP B CG    1 
ATOM 2323 O OD1   . ASP B 2 114 ? 168.678 134.384 205.074 1.00 127.36 ? 114 ASP B OD1   1 
ATOM 2324 O OD2   . ASP B 2 114 ? 169.392 134.759 207.092 1.00 128.53 ? 114 ASP B OD2   1 
ATOM 2325 N N     . TYR B 2 115 ? 167.002 137.385 208.268 1.00 109.50 ? 115 TYR B N     1 
ATOM 2326 C CA    . TYR B 2 115 ? 167.611 138.645 208.671 1.00 104.81 ? 115 TYR B CA    1 
ATOM 2327 C C     . TYR B 2 115 ? 167.545 138.884 210.179 1.00 100.86 ? 115 TYR B C     1 
ATOM 2328 O O     . TYR B 2 115 ? 167.800 140.007 210.627 1.00 98.27  ? 115 TYR B O     1 
ATOM 2329 C CB    . TYR B 2 115 ? 166.947 139.810 207.936 1.00 98.98  ? 115 TYR B CB    1 
ATOM 2330 C CG    . TYR B 2 115 ? 167.682 140.265 206.698 1.00 97.31  ? 115 TYR B CG    1 
ATOM 2331 C CD1   . TYR B 2 115 ? 169.016 140.639 206.757 1.00 101.74 ? 115 TYR B CD1   1 
ATOM 2332 C CD2   . TYR B 2 115 ? 167.035 140.342 205.475 1.00 101.76 ? 115 TYR B CD2   1 
ATOM 2333 C CE1   . TYR B 2 115 ? 169.685 141.067 205.633 1.00 103.06 ? 115 TYR B CE1   1 
ATOM 2334 C CE2   . TYR B 2 115 ? 167.694 140.768 204.346 1.00 104.65 ? 115 TYR B CE2   1 
ATOM 2335 C CZ    . TYR B 2 115 ? 169.020 141.129 204.429 1.00 104.83 ? 115 TYR B CZ    1 
ATOM 2336 O OH    . TYR B 2 115 ? 169.689 141.553 203.305 1.00 101.25 ? 115 TYR B OH    1 
ATOM 2337 N N     . GLY B 2 116 ? 167.183 137.871 210.965 1.00 103.09 ? 116 GLY B N     1 
ATOM 2338 C CA    . GLY B 2 116 ? 167.196 137.965 212.407 1.00 104.97 ? 116 GLY B CA    1 
ATOM 2339 C C     . GLY B 2 116 ? 166.015 138.678 213.018 1.00 106.05 ? 116 GLY B C     1 
ATOM 2340 O O     . GLY B 2 116 ? 165.988 138.856 214.241 1.00 108.16 ? 116 GLY B O     1 
ATOM 2341 N N     . ILE B 2 117 ? 165.037 139.085 212.220 1.00 97.69  ? 117 ILE B N     1 
ATOM 2342 C CA    . ILE B 2 117 ? 163.909 139.845 212.739 1.00 92.17  ? 117 ILE B CA    1 
ATOM 2343 C C     . ILE B 2 117 ? 162.891 138.879 213.327 1.00 96.15  ? 117 ILE B C     1 
ATOM 2344 O O     . ILE B 2 117 ? 162.460 137.929 212.663 1.00 98.86  ? 117 ILE B O     1 
ATOM 2345 C CB    . ILE B 2 117 ? 163.280 140.709 211.637 1.00 91.75  ? 117 ILE B CB    1 
ATOM 2346 C CG1   . ILE B 2 117 ? 164.311 141.690 211.084 1.00 92.97  ? 117 ILE B CG1   1 
ATOM 2347 C CG2   . ILE B 2 117 ? 162.099 141.482 212.195 1.00 92.12  ? 117 ILE B CG2   1 
ATOM 2348 C CD1   . ILE B 2 117 ? 163.709 142.838 210.319 1.00 93.43  ? 117 ILE B CD1   1 
ATOM 2349 N N     . ARG B 2 118 ? 162.512 139.116 214.575 1.00 114.71 ? 118 ARG B N     1 
ATOM 2350 C CA    . ARG B 2 118 ? 161.484 138.358 215.270 1.00 113.46 ? 118 ARG B CA    1 
ATOM 2351 C C     . ARG B 2 118 ? 160.279 139.260 215.500 1.00 111.79 ? 118 ARG B C     1 
ATOM 2352 O O     . ARG B 2 118 ? 160.259 140.423 215.093 1.00 116.81 ? 118 ARG B O     1 
ATOM 2353 C CB    . ARG B 2 118 ? 162.014 137.808 216.597 1.00 113.25 ? 118 ARG B CB    1 
ATOM 2354 C CG    . ARG B 2 118 ? 163.399 137.193 216.505 1.00 113.10 ? 118 ARG B CG    1 
ATOM 2355 C CD    . ARG B 2 118 ? 163.333 135.676 216.517 1.00 111.76 ? 118 ARG B CD    1 
ATOM 2356 N NE    . ARG B 2 118 ? 162.901 135.138 215.233 1.00 116.00 ? 118 ARG B NE    1 
ATOM 2357 C CZ    . ARG B 2 118 ? 163.642 135.122 214.133 1.00 116.22 ? 118 ARG B CZ    1 
ATOM 2358 N NH1   . ARG B 2 118 ? 164.872 135.608 214.120 1.00 113.28 ? 118 ARG B NH1   1 
ATOM 2359 N NH2   . ARG B 2 118 ? 163.135 134.606 213.018 1.00 114.35 ? 118 ARG B NH2   1 
ATOM 2360 N N     . ASN B 2 119 ? 159.264 138.716 216.158 1.00 98.10  ? 119 ASN B N     1 
ATOM 2361 C CA    . ASN B 2 119 ? 158.104 139.520 216.501 1.00 100.60 ? 119 ASN B CA    1 
ATOM 2362 C C     . ASN B 2 119 ? 158.479 140.558 217.550 1.00 100.46 ? 119 ASN B C     1 
ATOM 2363 O O     . ASN B 2 119 ? 159.385 140.352 218.361 1.00 98.55  ? 119 ASN B O     1 
ATOM 2364 C CB    . ASN B 2 119 ? 156.969 138.632 217.007 1.00 98.67  ? 119 ASN B CB    1 
ATOM 2365 C CG    . ASN B 2 119 ? 156.950 138.510 218.515 1.00 105.15 ? 119 ASN B CG    1 
ATOM 2366 O OD1   . ASN B 2 119 ? 156.355 139.334 219.213 1.00 109.23 ? 119 ASN B OD1   1 
ATOM 2367 N ND2   . ASN B 2 119 ? 157.610 137.480 219.030 1.00 106.21 ? 119 ASN B ND2   1 
ATOM 2368 N N     . ARG B 2 120 ? 157.779 141.692 217.514 1.00 110.90 ? 120 ARG B N     1 
ATOM 2369 C CA    . ARG B 2 120 ? 157.973 142.773 218.481 1.00 112.39 ? 120 ARG B CA    1 
ATOM 2370 C C     . ARG B 2 120 ? 159.408 143.303 218.425 1.00 109.76 ? 120 ARG B C     1 
ATOM 2371 O O     . ARG B 2 120 ? 159.957 143.783 219.417 1.00 111.68 ? 120 ARG B O     1 
ATOM 2372 C CB    . ARG B 2 120 ? 157.593 142.302 219.896 1.00 115.39 ? 120 ARG B CB    1 
ATOM 2373 C CG    . ARG B 2 120 ? 157.633 143.336 221.039 1.00 114.32 ? 120 ARG B CG    1 
ATOM 2374 C CD    . ARG B 2 120 ? 156.680 144.516 220.858 1.00 113.86 ? 120 ARG B CD    1 
ATOM 2375 N NE    . ARG B 2 120 ? 155.588 144.240 219.932 1.00 117.11 ? 120 ARG B NE    1 
ATOM 2376 C CZ    . ARG B 2 120 ? 154.484 143.573 220.245 1.00 115.57 ? 120 ARG B CZ    1 
ATOM 2377 N NH1   . ARG B 2 120 ? 154.279 143.107 221.466 1.00 113.88 ? 120 ARG B NH1   1 
ATOM 2378 N NH2   . ARG B 2 120 ? 153.565 143.365 219.308 1.00 113.83 ? 120 ARG B NH2   1 
ATOM 2379 N N     . ASP B 2 121 ? 160.035 143.226 217.255 1.00 115.87 ? 121 ASP B N     1 
ATOM 2380 C CA    . ASP B 2 121 ? 161.399 143.706 217.105 1.00 120.82 ? 121 ASP B CA    1 
ATOM 2381 C C     . ASP B 2 121 ? 161.412 145.192 216.760 1.00 117.27 ? 121 ASP B C     1 
ATOM 2382 O O     . ASP B 2 121 ? 160.380 145.865 216.723 1.00 117.97 ? 121 ASP B O     1 
ATOM 2383 C CB    . ASP B 2 121 ? 162.136 142.901 216.039 1.00 119.09 ? 121 ASP B CB    1 
ATOM 2384 C CG    . ASP B 2 121 ? 162.651 141.586 216.564 1.00 121.34 ? 121 ASP B CG    1 
ATOM 2385 O OD1   . ASP B 2 121 ? 162.317 141.240 217.715 1.00 122.58 ? 121 ASP B OD1   1 
ATOM 2386 O OD2   . ASP B 2 121 ? 163.400 140.903 215.835 1.00 119.82 ? 121 ASP B OD2   1 
ATOM 2387 N N     . GLU B 2 122 ? 162.609 145.715 216.511 1.00 105.33 ? 122 GLU B N     1 
ATOM 2388 C CA    . GLU B 2 122 ? 162.795 147.103 216.120 1.00 106.60 ? 122 GLU B CA    1 
ATOM 2389 C C     . GLU B 2 122 ? 163.779 147.183 214.965 1.00 108.36 ? 122 GLU B C     1 
ATOM 2390 O O     . GLU B 2 122 ? 164.839 146.551 215.004 1.00 111.07 ? 122 GLU B O     1 
ATOM 2391 C CB    . GLU B 2 122 ? 163.288 147.949 217.299 1.00 110.57 ? 122 GLU B CB    1 
ATOM 2392 C CG    . GLU B 2 122 ? 163.946 149.275 216.917 1.00 116.31 ? 122 GLU B CG    1 
ATOM 2393 C CD    . GLU B 2 122 ? 163.041 150.214 216.138 1.00 117.63 ? 122 GLU B CD    1 
ATOM 2394 O OE1   . GLU B 2 122 ? 161.824 149.956 216.046 1.00 120.76 ? 122 GLU B OE1   1 
ATOM 2395 O OE2   . GLU B 2 122 ? 163.552 151.230 215.624 1.00 112.80 ? 122 GLU B OE2   1 
ATOM 2396 N N     . VAL B 2 123 ? 163.419 147.949 213.934 1.00 88.04  ? 123 VAL B N     1 
ATOM 2397 C CA    . VAL B 2 123 ? 164.323 148.273 212.840 1.00 92.38  ? 123 VAL B CA    1 
ATOM 2398 C C     . VAL B 2 123 ? 164.280 149.779 212.626 1.00 94.12  ? 123 VAL B C     1 
ATOM 2399 O O     . VAL B 2 123 ? 163.300 150.452 212.954 1.00 91.40  ? 123 VAL B O     1 
ATOM 2400 C CB    . VAL B 2 123 ? 163.978 147.529 211.532 1.00 88.24  ? 123 VAL B CB    1 
ATOM 2401 C CG1   . VAL B 2 123 ? 163.851 146.045 211.785 1.00 90.96  ? 123 VAL B CG1   1 
ATOM 2402 C CG2   . VAL B 2 123 ? 162.707 148.073 210.931 1.00 87.89  ? 123 VAL B CG2   1 
ATOM 2403 N N     . SER B 2 124 ? 165.365 150.307 212.065 1.00 84.15  ? 124 SER B N     1 
ATOM 2404 C CA    . SER B 2 124 ? 165.537 151.744 211.930 1.00 81.43  ? 124 SER B CA    1 
ATOM 2405 C C     . SER B 2 124 ? 165.907 152.073 210.492 1.00 80.16  ? 124 SER B C     1 
ATOM 2406 O O     . SER B 2 124 ? 166.056 151.189 209.643 1.00 81.64  ? 124 SER B O     1 
ATOM 2407 C CB    . SER B 2 124 ? 166.597 152.265 212.904 1.00 85.87  ? 124 SER B CB    1 
ATOM 2408 O OG    . SER B 2 124 ? 166.211 152.033 214.247 1.00 88.90  ? 124 SER B OG    1 
ATOM 2409 N N     . PHE B 2 125 ? 166.064 153.364 210.228 1.00 70.89  ? 125 PHE B N     1 
ATOM 2410 C CA    . PHE B 2 125 ? 166.383 153.884 208.911 1.00 71.40  ? 125 PHE B CA    1 
ATOM 2411 C C     . PHE B 2 125 ? 167.833 154.343 208.857 1.00 79.10  ? 125 PHE B C     1 
ATOM 2412 O O     . PHE B 2 125 ? 168.423 154.719 209.873 1.00 87.21  ? 125 PHE B O     1 
ATOM 2413 C CB    . PHE B 2 125 ? 165.476 155.061 208.556 1.00 74.33  ? 125 PHE B CB    1 
ATOM 2414 C CG    . PHE B 2 125 ? 164.046 154.684 208.333 1.00 70.06  ? 125 PHE B CG    1 
ATOM 2415 C CD1   . PHE B 2 125 ? 163.696 153.804 207.328 1.00 75.60  ? 125 PHE B CD1   1 
ATOM 2416 C CD2   . PHE B 2 125 ? 163.049 155.214 209.129 1.00 71.21  ? 125 PHE B CD2   1 
ATOM 2417 C CE1   . PHE B 2 125 ? 162.379 153.464 207.119 1.00 74.76  ? 125 PHE B CE1   1 
ATOM 2418 C CE2   . PHE B 2 125 ? 161.730 154.875 208.925 1.00 70.89  ? 125 PHE B CE2   1 
ATOM 2419 C CZ    . PHE B 2 125 ? 161.396 153.999 207.920 1.00 72.70  ? 125 PHE B CZ    1 
ATOM 2420 N N     . ILE B 2 126 ? 168.401 154.314 207.653 1.00 72.39  ? 126 ILE B N     1 
ATOM 2421 C CA    . ILE B 2 126 ? 169.739 154.838 207.416 1.00 67.38  ? 126 ILE B CA    1 
ATOM 2422 C C     . ILE B 2 126 ? 169.838 155.165 205.936 1.00 73.01  ? 126 ILE B C     1 
ATOM 2423 O O     . ILE B 2 126 ? 169.161 154.554 205.107 1.00 86.54  ? 126 ILE B O     1 
ATOM 2424 C CB    . ILE B 2 126 ? 170.829 153.833 207.869 1.00 73.77  ? 126 ILE B CB    1 
ATOM 2425 C CG1   . ILE B 2 126 ? 172.073 154.574 208.353 1.00 79.45  ? 126 ILE B CG1   1 
ATOM 2426 C CG2   . ILE B 2 126 ? 171.197 152.881 206.750 1.00 77.42  ? 126 ILE B CG2   1 
ATOM 2427 C CD1   . ILE B 2 126 ? 173.027 153.702 209.132 1.00 78.50  ? 126 ILE B CD1   1 
ATOM 2428 N N     . LYS B 2 127 ? 170.665 156.150 205.607 1.00 68.39  ? 127 LYS B N     1 
ATOM 2429 C CA    . LYS B 2 127 ? 170.795 156.562 204.220 1.00 76.60  ? 127 LYS B CA    1 
ATOM 2430 C C     . LYS B 2 127 ? 171.653 155.566 203.444 1.00 77.79  ? 127 LYS B C     1 
ATOM 2431 O O     . LYS B 2 127 ? 172.354 154.728 204.016 1.00 83.11  ? 127 LYS B O     1 
ATOM 2432 C CB    . LYS B 2 127 ? 171.376 157.969 204.137 1.00 73.82  ? 127 LYS B CB    1 
ATOM 2433 C CG    . LYS B 2 127 ? 170.774 158.921 205.149 1.00 73.63  ? 127 LYS B CG    1 
ATOM 2434 C CD    . LYS B 2 127 ? 170.728 160.338 204.617 1.00 71.99  ? 127 LYS B CD    1 
ATOM 2435 C CE    . LYS B 2 127 ? 170.324 161.313 205.705 1.00 77.58  ? 127 LYS B CE    1 
ATOM 2436 N NZ    . LYS B 2 127 ? 171.256 161.263 206.862 1.00 72.94  ? 127 LYS B NZ    1 
ATOM 2437 N N     . LYS B 2 128 ? 171.580 155.658 202.120 1.00 77.66  ? 128 LYS B N     1 
ATOM 2438 C CA    . LYS B 2 128 ? 172.279 154.725 201.241 1.00 81.41  ? 128 LYS B CA    1 
ATOM 2439 C C     . LYS B 2 128 ? 173.790 154.715 201.465 1.00 94.12  ? 128 LYS B C     1 
ATOM 2440 O O     . LYS B 2 128 ? 174.353 153.722 201.924 1.00 98.06  ? 128 LYS B O     1 
ATOM 2441 C CB    . LYS B 2 128 ? 171.987 155.059 199.780 1.00 87.74  ? 128 LYS B CB    1 
ATOM 2442 C CG    . LYS B 2 128 ? 170.676 154.508 199.247 1.00 88.13  ? 128 LYS B CG    1 
ATOM 2443 C CD    . LYS B 2 128 ? 170.707 152.994 199.131 1.00 86.68  ? 128 LYS B CD    1 
ATOM 2444 C CE    . LYS B 2 128 ? 169.327 152.393 199.343 1.00 83.32  ? 128 LYS B CE    1 
ATOM 2445 N NZ    . LYS B 2 128 ? 168.322 152.961 198.410 1.00 83.58  ? 128 LYS B NZ    1 
ATOM 2446 N N     . GLU C 3 10  ? 165.384 189.452 193.901 1.00 72.40  ? 10  GLU C N     1 
ATOM 2447 C CA    . GLU C 3 10  ? 164.860 189.145 192.578 1.00 77.52  ? 10  GLU C CA    1 
ATOM 2448 C C     . GLU C 3 10  ? 165.580 187.941 191.990 1.00 74.95  ? 10  GLU C C     1 
ATOM 2449 O O     . GLU C 3 10  ? 166.529 188.090 191.226 1.00 77.01  ? 10  GLU C O     1 
ATOM 2450 C CB    . GLU C 3 10  ? 165.000 190.353 191.651 1.00 81.78  ? 10  GLU C CB    1 
ATOM 2451 C CG    . GLU C 3 10  ? 164.082 191.515 191.997 1.00 82.97  ? 10  GLU C CG    1 
ATOM 2452 C CD    . GLU C 3 10  ? 164.570 192.314 193.191 1.00 88.62  ? 10  GLU C CD    1 
ATOM 2453 O OE1   . GLU C 3 10  ? 165.799 192.470 193.342 1.00 80.87  ? 10  GLU C OE1   1 
ATOM 2454 O OE2   . GLU C 3 10  ? 163.724 192.784 193.980 1.00 87.30  ? 10  GLU C OE2   1 
ATOM 2455 N N     . TYR C 3 11  ? 165.121 186.748 192.351 1.00 68.97  ? 11  TYR C N     1 
ATOM 2456 C CA    . TYR C 3 11  ? 165.796 185.531 191.930 1.00 66.40  ? 11  TYR C CA    1 
ATOM 2457 C C     . TYR C 3 11  ? 165.653 185.318 190.433 1.00 63.62  ? 11  TYR C C     1 
ATOM 2458 O O     . TYR C 3 11  ? 164.567 185.455 189.867 1.00 76.88  ? 11  TYR C O     1 
ATOM 2459 C CB    . TYR C 3 11  ? 165.234 184.326 192.675 1.00 73.20  ? 11  TYR C CB    1 
ATOM 2460 C CG    . TYR C 3 11  ? 166.068 183.076 192.556 1.00 68.20  ? 11  TYR C CG    1 
ATOM 2461 C CD1   . TYR C 3 11  ? 167.256 182.941 193.249 1.00 66.91  ? 11  TYR C CD1   1 
ATOM 2462 C CD2   . TYR C 3 11  ? 165.659 182.025 191.758 1.00 68.70  ? 11  TYR C CD2   1 
ATOM 2463 C CE1   . TYR C 3 11  ? 168.012 181.796 193.145 1.00 67.05  ? 11  TYR C CE1   1 
ATOM 2464 C CE2   . TYR C 3 11  ? 166.408 180.879 191.650 1.00 70.13  ? 11  TYR C CE2   1 
ATOM 2465 C CZ    . TYR C 3 11  ? 167.581 180.769 192.344 1.00 65.61  ? 11  TYR C CZ    1 
ATOM 2466 O OH    . TYR C 3 11  ? 168.329 179.623 192.232 1.00 64.65  ? 11  TYR C OH    1 
ATOM 2467 N N     . ASP C 3 12  ? 166.758 184.979 189.797 1.00 80.86  ? 12  ASP C N     1 
ATOM 2468 C CA    . ASP C 3 12  ? 166.782 184.610 188.392 1.00 86.62  ? 12  ASP C CA    1 
ATOM 2469 C C     . ASP C 3 12  ? 167.650 183.371 188.248 1.00 86.82  ? 12  ASP C C     1 
ATOM 2470 O O     . ASP C 3 12  ? 168.875 183.458 188.395 1.00 90.84  ? 12  ASP C O     1 
ATOM 2471 C CB    . ASP C 3 12  ? 167.323 185.752 187.532 1.00 93.85  ? 12  ASP C CB    1 
ATOM 2472 C CG    . ASP C 3 12  ? 166.226 186.623 186.958 1.00 96.09  ? 12  ASP C CG    1 
ATOM 2473 O OD1   . ASP C 3 12  ? 165.047 186.412 187.308 1.00 91.22  ? 12  ASP C OD1   1 
ATOM 2474 O OD2   . ASP C 3 12  ? 166.544 187.523 186.153 1.00 96.61  ? 12  ASP C OD2   1 
ATOM 2475 N N     . PRO C 3 13  ? 167.065 182.208 187.976 1.00 72.11  ? 13  PRO C N     1 
ATOM 2476 C CA    . PRO C 3 13  ? 167.875 180.990 187.850 1.00 68.49  ? 13  PRO C CA    1 
ATOM 2477 C C     . PRO C 3 13  ? 168.926 181.121 186.765 1.00 77.98  ? 13  PRO C C     1 
ATOM 2478 O O     . PRO C 3 13  ? 169.944 180.429 186.795 1.00 86.28  ? 13  PRO C O     1 
ATOM 2479 C CB    . PRO C 3 13  ? 166.853 179.902 187.501 1.00 70.86  ? 13  PRO C CB    1 
ATOM 2480 C CG    . PRO C 3 13  ? 165.511 180.493 187.725 1.00 83.15  ? 13  PRO C CG    1 
ATOM 2481 C CD    . PRO C 3 13  ? 165.628 181.930 188.103 1.00 82.51  ? 13  PRO C CD    1 
ATOM 2482 N N     . LEU C 3 14  ? 168.696 182.028 185.817 1.00 108.06 ? 14  LEU C N     1 
ATOM 2483 C CA    . LEU C 3 14  ? 169.662 182.275 184.752 1.00 111.14 ? 14  LEU C CA    1 
ATOM 2484 C C     . LEU C 3 14  ? 170.986 182.783 185.308 1.00 111.54 ? 14  LEU C C     1 
ATOM 2485 O O     . LEU C 3 14  ? 172.015 182.107 185.210 1.00 112.00 ? 14  LEU C O     1 
ATOM 2486 C CB    . LEU C 3 14  ? 169.084 183.281 183.755 1.00 108.31 ? 14  LEU C CB    1 
ATOM 2487 C CG    . LEU C 3 14  ? 169.624 183.273 182.326 1.00 112.04 ? 14  LEU C CG    1 
ATOM 2488 C CD1   . LEU C 3 14  ? 170.074 181.886 181.939 1.00 110.43 ? 14  LEU C CD1   1 
ATOM 2489 C CD2   . LEU C 3 14  ? 168.562 183.780 181.365 1.00 114.69 ? 14  LEU C CD2   1 
ATOM 2490 N N     . LYS C 3 15  ? 170.970 183.969 185.916 1.00 107.29 ? 15  LYS C N     1 
ATOM 2491 C CA    . LYS C 3 15  ? 172.204 184.574 186.397 1.00 108.05 ? 15  LYS C CA    1 
ATOM 2492 C C     . LYS C 3 15  ? 172.688 183.951 187.699 1.00 109.88 ? 15  LYS C C     1 
ATOM 2493 O O     . LYS C 3 15  ? 173.845 184.164 188.080 1.00 113.70 ? 15  LYS C O     1 
ATOM 2494 C CB    . LYS C 3 15  ? 172.004 186.078 186.572 1.00 111.53 ? 15  LYS C CB    1 
ATOM 2495 C CG    . LYS C 3 15  ? 170.977 186.442 187.623 1.00 110.35 ? 15  LYS C CG    1 
ATOM 2496 C CD    . LYS C 3 15  ? 171.091 187.902 188.024 1.00 111.49 ? 15  LYS C CD    1 
ATOM 2497 C CE    . LYS C 3 15  ? 170.926 188.821 186.827 1.00 111.59 ? 15  LYS C CE    1 
ATOM 2498 N NZ    . LYS C 3 15  ? 169.532 188.801 186.306 1.00 110.25 ? 15  LYS C NZ    1 
ATOM 2499 N N     . ALA C 3 16  ? 171.839 183.180 188.380 1.00 102.11 ? 16  ALA C N     1 
ATOM 2500 C CA    . ALA C 3 16  ? 172.239 182.580 189.648 1.00 104.24 ? 16  ALA C CA    1 
ATOM 2501 C C     . ALA C 3 16  ? 173.396 181.610 189.471 1.00 102.71 ? 16  ALA C C     1 
ATOM 2502 O O     . ALA C 3 16  ? 174.184 181.411 190.401 1.00 107.95 ? 16  ALA C O     1 
ATOM 2503 C CB    . ALA C 3 16  ? 171.049 181.875 190.294 1.00 102.85 ? 16  ALA C CB    1 
ATOM 2504 N N     . GLY C 3 17  ? 173.518 181.001 188.301 1.00 104.16 ? 17  GLY C N     1 
ATOM 2505 C CA    . GLY C 3 17  ? 174.619 180.104 188.040 1.00 107.38 ? 17  GLY C CA    1 
ATOM 2506 C C     . GLY C 3 17  ? 175.905 180.783 187.625 1.00 117.36 ? 17  GLY C C     1 
ATOM 2507 O O     . GLY C 3 17  ? 176.895 180.096 187.353 1.00 116.78 ? 17  GLY C O     1 
ATOM 2508 N N     . SER C 3 18  ? 175.923 182.112 187.571 1.00 130.08 ? 18  SER C N     1 
ATOM 2509 C CA    . SER C 3 18  ? 177.080 182.871 187.124 1.00 124.77 ? 18  SER C CA    1 
ATOM 2510 C C     . SER C 3 18  ? 177.567 183.789 188.234 1.00 120.88 ? 18  SER C C     1 
ATOM 2511 O O     . SER C 3 18  ? 176.773 184.283 189.040 1.00 122.79 ? 18  SER C O     1 
ATOM 2512 C CB    . SER C 3 18  ? 176.748 183.696 185.884 1.00 129.76 ? 18  SER C CB    1 
ATOM 2513 O OG    . SER C 3 18  ? 176.108 184.903 186.242 1.00 129.37 ? 18  SER C OG    1 
ATOM 2514 N N     . ILE C 3 19  ? 178.879 184.028 188.251 1.00 118.75 ? 19  ILE C N     1 
ATOM 2515 C CA    . ILE C 3 19  ? 179.494 184.766 189.349 1.00 123.74 ? 19  ILE C CA    1 
ATOM 2516 C C     . ILE C 3 19  ? 179.044 186.221 189.345 1.00 126.16 ? 19  ILE C C     1 
ATOM 2517 O O     . ILE C 3 19  ? 178.806 186.814 190.405 1.00 125.61 ? 19  ILE C O     1 
ATOM 2518 C CB    . ILE C 3 19  ? 181.027 184.643 189.276 1.00 123.53 ? 19  ILE C CB    1 
ATOM 2519 C CG1   . ILE C 3 19  ? 181.441 183.170 189.282 1.00 123.35 ? 19  ILE C CG1   1 
ATOM 2520 C CG2   . ILE C 3 19  ? 181.674 185.364 190.442 1.00 121.14 ? 19  ILE C CG2   1 
ATOM 2521 C CD1   . ILE C 3 19  ? 181.736 182.602 187.912 1.00 126.01 ? 19  ILE C CD1   1 
ATOM 2522 N N     . ASP C 3 20  ? 178.919 186.823 188.164 1.00 144.87 ? 20  ASP C N     1 
ATOM 2523 C CA    . ASP C 3 20  ? 178.639 188.248 188.054 1.00 146.12 ? 20  ASP C CA    1 
ATOM 2524 C C     . ASP C 3 20  ? 177.333 188.559 187.332 1.00 144.75 ? 20  ASP C C     1 
ATOM 2525 O O     . ASP C 3 20  ? 177.095 189.719 186.983 1.00 145.26 ? 20  ASP C O     1 
ATOM 2526 C CB    . ASP C 3 20  ? 179.800 188.955 187.354 1.00 146.82 ? 20  ASP C CB    1 
ATOM 2527 C CG    . ASP C 3 20  ? 180.286 188.204 186.135 1.00 146.88 ? 20  ASP C CG    1 
ATOM 2528 O OD1   . ASP C 3 20  ? 179.635 187.212 185.749 1.00 143.72 ? 20  ASP C OD1   1 
ATOM 2529 O OD2   . ASP C 3 20  ? 181.318 188.608 185.562 1.00 146.85 ? 20  ASP C OD2   1 
ATOM 2530 N N     . GLY C 3 21  ? 176.478 187.566 187.105 1.00 140.36 ? 21  GLY C N     1 
ATOM 2531 C CA    . GLY C 3 21  ? 175.222 187.827 186.428 1.00 137.82 ? 21  GLY C CA    1 
ATOM 2532 C C     . GLY C 3 21  ? 175.335 188.067 184.942 1.00 142.02 ? 21  GLY C C     1 
ATOM 2533 O O     . GLY C 3 21  ? 174.462 188.721 184.364 1.00 140.92 ? 21  GLY C O     1 
ATOM 2534 N N     . THR C 3 22  ? 176.389 187.556 184.301 1.00 159.34 ? 22  THR C N     1 
ATOM 2535 C CA    . THR C 3 22  ? 176.623 187.768 182.880 1.00 158.81 ? 22  THR C CA    1 
ATOM 2536 C C     . THR C 3 22  ? 176.371 186.544 182.012 1.00 157.11 ? 22  THR C C     1 
ATOM 2537 O O     . THR C 3 22  ? 176.561 186.629 180.794 1.00 158.83 ? 22  THR C O     1 
ATOM 2538 C CB    . THR C 3 22  ? 178.063 188.252 182.640 1.00 158.52 ? 22  THR C CB    1 
ATOM 2539 O OG1   . THR C 3 22  ? 178.116 189.022 181.433 1.00 158.38 ? 22  THR C OG1   1 
ATOM 2540 C CG2   . THR C 3 22  ? 179.034 187.073 182.551 1.00 158.56 ? 22  THR C CG2   1 
ATOM 2541 N N     . ASP C 3 23  ? 175.966 185.417 182.587 1.00 150.16 ? 23  ASP C N     1 
ATOM 2542 C CA    . ASP C 3 23  ? 175.745 184.227 181.780 1.00 153.10 ? 23  ASP C CA    1 
ATOM 2543 C C     . ASP C 3 23  ? 174.368 184.273 181.129 1.00 155.26 ? 23  ASP C C     1 
ATOM 2544 O O     . ASP C 3 23  ? 173.365 184.584 181.777 1.00 154.24 ? 23  ASP C O     1 
ATOM 2545 C CB    . ASP C 3 23  ? 175.890 182.975 182.642 1.00 152.62 ? 23  ASP C CB    1 
ATOM 2546 C CG    . ASP C 3 23  ? 175.909 181.701 181.827 1.00 154.93 ? 23  ASP C CG    1 
ATOM 2547 O OD1   . ASP C 3 23  ? 175.859 181.781 180.582 1.00 155.72 ? 23  ASP C OD1   1 
ATOM 2548 O OD2   . ASP C 3 23  ? 176.005 180.617 182.436 1.00 154.78 ? 23  ASP C OD2   1 
ATOM 2549 N N     . GLU C 3 24  ? 174.327 183.978 179.828 1.00 158.80 ? 24  GLU C N     1 
ATOM 2550 C CA    . GLU C 3 24  ? 173.076 183.868 179.085 1.00 156.65 ? 24  GLU C CA    1 
ATOM 2551 C C     . GLU C 3 24  ? 172.733 182.437 178.691 1.00 157.15 ? 24  GLU C C     1 
ATOM 2552 O O     . GLU C 3 24  ? 171.765 182.229 177.950 1.00 157.43 ? 24  GLU C O     1 
ATOM 2553 C CB    . GLU C 3 24  ? 173.097 184.748 177.827 1.00 158.42 ? 24  GLU C CB    1 
ATOM 2554 C CG    . GLU C 3 24  ? 173.662 186.184 177.918 1.00 159.59 ? 24  GLU C CG    1 
ATOM 2555 C CD    . GLU C 3 24  ? 173.546 186.864 179.280 1.00 159.57 ? 24  GLU C CD    1 
ATOM 2556 O OE1   . GLU C 3 24  ? 174.426 187.694 179.586 1.00 158.04 ? 24  GLU C OE1   1 
ATOM 2557 O OE2   . GLU C 3 24  ? 172.558 186.642 180.012 1.00 159.27 ? 24  GLU C OE2   1 
ATOM 2558 N N     . ASP C 3 25  ? 173.490 181.444 179.160 1.00 160.15 ? 25  ASP C N     1 
ATOM 2559 C CA    . ASP C 3 25  ? 173.154 180.062 178.854 1.00 159.36 ? 25  ASP C CA    1 
ATOM 2560 C C     . ASP C 3 25  ? 173.467 179.172 180.051 1.00 160.22 ? 25  ASP C C     1 
ATOM 2561 O O     . ASP C 3 25  ? 174.612 179.181 180.529 1.00 162.03 ? 25  ASP C O     1 
ATOM 2562 C CB    . ASP C 3 25  ? 173.899 179.567 177.612 1.00 158.93 ? 25  ASP C CB    1 
ATOM 2563 C CG    . ASP C 3 25  ? 175.403 179.522 177.805 1.00 160.90 ? 25  ASP C CG    1 
ATOM 2564 O OD1   . ASP C 3 25  ? 176.007 180.589 178.043 1.00 161.97 ? 25  ASP C OD1   1 
ATOM 2565 O OD2   . ASP C 3 25  ? 175.980 178.419 177.714 1.00 159.93 ? 25  ASP C OD2   1 
ATOM 2566 N N     . PRO C 3 26  ? 172.473 178.444 180.580 1.00 138.41 ? 26  PRO C N     1 
ATOM 2567 C CA    . PRO C 3 26  ? 172.719 177.518 181.690 1.00 135.59 ? 26  PRO C CA    1 
ATOM 2568 C C     . PRO C 3 26  ? 173.950 176.649 181.508 1.00 137.56 ? 26  PRO C C     1 
ATOM 2569 O O     . PRO C 3 26  ? 174.064 175.929 180.512 1.00 138.38 ? 26  PRO C O     1 
ATOM 2570 C CB    . PRO C 3 26  ? 171.443 176.658 181.678 1.00 136.53 ? 26  PRO C CB    1 
ATOM 2571 C CG    . PRO C 3 26  ? 170.423 177.494 180.809 1.00 135.73 ? 26  PRO C CG    1 
ATOM 2572 C CD    . PRO C 3 26  ? 171.064 178.836 180.660 1.00 135.52 ? 26  PRO C CD    1 
ATOM 2573 N N     . HIS C 3 27  ? 174.873 176.704 182.461 1.00 129.26 ? 27  HIS C N     1 
ATOM 2574 C CA    . HIS C 3 27  ? 176.048 175.849 182.426 1.00 130.45 ? 27  HIS C CA    1 
ATOM 2575 C C     . HIS C 3 27  ? 175.826 174.527 183.140 1.00 127.21 ? 27  HIS C C     1 
ATOM 2576 O O     . HIS C 3 27  ? 176.759 173.723 183.238 1.00 129.90 ? 27  HIS C O     1 
ATOM 2577 C CB    . HIS C 3 27  ? 177.250 176.568 183.044 1.00 131.24 ? 27  HIS C CB    1 
ATOM 2578 C CG    . HIS C 3 27  ? 177.023 177.027 184.449 1.00 128.27 ? 27  HIS C CG    1 
ATOM 2579 N ND1   . HIS C 3 27  ? 177.631 176.432 185.533 1.00 128.01 ? 27  HIS C ND1   1 
ATOM 2580 C CD2   . HIS C 3 27  ? 176.252 178.021 184.949 1.00 127.64 ? 27  HIS C CD2   1 
ATOM 2581 C CE1   . HIS C 3 27  ? 177.249 177.044 186.639 1.00 129.02 ? 27  HIS C CE1   1 
ATOM 2582 N NE2   . HIS C 3 27  ? 176.411 178.011 186.313 1.00 128.52 ? 27  HIS C NE2   1 
ATOM 2583 N N     . ASP C 3 28  ? 174.621 174.289 183.640 1.00 114.15 ? 28  ASP C N     1 
ATOM 2584 C CA    . ASP C 3 28  ? 174.302 173.091 184.396 1.00 116.14 ? 28  ASP C CA    1 
ATOM 2585 C C     . ASP C 3 28  ? 172.862 172.707 184.092 1.00 117.20 ? 28  ASP C C     1 
ATOM 2586 O O     . ASP C 3 28  ? 171.994 173.580 184.004 1.00 119.00 ? 28  ASP C O     1 
ATOM 2587 C CB    . ASP C 3 28  ? 174.472 173.339 185.894 1.00 117.67 ? 28  ASP C CB    1 
ATOM 2588 C CG    . ASP C 3 28  ? 174.941 172.124 186.631 1.00 120.44 ? 28  ASP C CG    1 
ATOM 2589 O OD1   . ASP C 3 28  ? 174.796 172.076 187.870 1.00 122.09 ? 28  ASP C OD1   1 
ATOM 2590 O OD2   . ASP C 3 28  ? 175.517 171.242 185.978 1.00 123.50 ? 28  ASP C OD2   1 
ATOM 2591 N N     . ARG C 3 29  ? 172.597 171.406 183.935 1.00 103.32 ? 29  ARG C N     1 
ATOM 2592 C CA    . ARG C 3 29  ? 171.217 170.991 183.691 1.00 102.27 ? 29  ARG C CA    1 
ATOM 2593 C C     . ARG C 3 29  ? 170.314 171.338 184.864 1.00 105.58 ? 29  ARG C C     1 
ATOM 2594 O O     . ARG C 3 29  ? 169.117 171.577 184.674 1.00 105.82 ? 29  ARG C O     1 
ATOM 2595 C CB    . ARG C 3 29  ? 171.130 169.495 183.404 1.00 104.01 ? 29  ARG C CB    1 
ATOM 2596 C CG    . ARG C 3 29  ? 172.293 168.911 182.651 1.00 103.18 ? 29  ARG C CG    1 
ATOM 2597 C CD    . ARG C 3 29  ? 172.384 167.425 182.927 1.00 101.66 ? 29  ARG C CD    1 
ATOM 2598 N NE    . ARG C 3 29  ? 171.312 166.676 182.284 1.00 102.34 ? 29  ARG C NE    1 
ATOM 2599 C CZ    . ARG C 3 29  ? 171.245 166.424 180.984 1.00 107.72 ? 29  ARG C CZ    1 
ATOM 2600 N NH1   . ARG C 3 29  ? 172.184 166.835 180.148 1.00 108.85 ? 29  ARG C NH1   1 
ATOM 2601 N NH2   . ARG C 3 29  ? 170.208 165.739 180.510 1.00 106.03 ? 29  ARG C NH2   1 
ATOM 2602 N N     . ALA C 3 30  ? 170.861 171.358 186.081 1.00 103.03 ? 30  ALA C N     1 
ATOM 2603 C CA    . ALA C 3 30  ? 170.071 171.761 187.236 1.00 98.93  ? 30  ALA C CA    1 
ATOM 2604 C C     . ALA C 3 30  ? 169.573 173.191 187.093 1.00 99.47  ? 30  ALA C C     1 
ATOM 2605 O O     . ALA C 3 30  ? 168.449 173.502 187.505 1.00 104.64 ? 30  ALA C O     1 
ATOM 2606 C CB    . ALA C 3 30  ? 170.890 171.601 188.513 1.00 94.97  ? 30  ALA C CB    1 
ATOM 2607 N N     . VAL C 3 31  ? 170.388 174.074 186.514 1.00 97.72  ? 31  VAL C N     1 
ATOM 2608 C CA    . VAL C 3 31  ? 169.896 175.399 186.152 1.00 95.42  ? 31  VAL C CA    1 
ATOM 2609 C C     . VAL C 3 31  ? 168.772 175.283 185.140 1.00 100.98 ? 31  VAL C C     1 
ATOM 2610 O O     . VAL C 3 31  ? 167.757 175.984 185.232 1.00 104.83 ? 31  VAL C O     1 
ATOM 2611 C CB    . VAL C 3 31  ? 171.040 176.274 185.615 1.00 98.26  ? 31  VAL C CB    1 
ATOM 2612 C CG1   . VAL C 3 31  ? 170.666 177.727 185.719 1.00 98.77  ? 31  VAL C CG1   1 
ATOM 2613 C CG2   . VAL C 3 31  ? 172.301 176.015 186.396 1.00 104.01 ? 31  VAL C CG2   1 
ATOM 2614 N N     . TRP C 3 32  ? 168.937 174.400 184.154 1.00 110.02 ? 32  TRP C N     1 
ATOM 2615 C CA    . TRP C 3 32  ? 167.908 174.240 183.135 1.00 111.23 ? 32  TRP C CA    1 
ATOM 2616 C C     . TRP C 3 32  ? 166.610 173.754 183.764 1.00 110.80 ? 32  TRP C C     1 
ATOM 2617 O O     . TRP C 3 32  ? 165.525 174.238 183.423 1.00 110.72 ? 32  TRP C O     1 
ATOM 2618 C CB    . TRP C 3 32  ? 168.389 173.267 182.056 1.00 112.69 ? 32  TRP C CB    1 
ATOM 2619 C CG    . TRP C 3 32  ? 167.387 172.982 180.969 1.00 114.66 ? 32  TRP C CG    1 
ATOM 2620 C CD1   . TRP C 3 32  ? 167.052 171.761 180.459 1.00 114.56 ? 32  TRP C CD1   1 
ATOM 2621 C CD2   . TRP C 3 32  ? 166.658 173.949 180.203 1.00 117.72 ? 32  TRP C CD2   1 
ATOM 2622 N NE1   . TRP C 3 32  ? 166.124 171.905 179.456 1.00 114.81 ? 32  TRP C NE1   1 
ATOM 2623 C CE2   . TRP C 3 32  ? 165.870 173.239 179.277 1.00 117.43 ? 32  TRP C CE2   1 
ATOM 2624 C CE3   . TRP C 3 32  ? 166.581 175.345 180.222 1.00 115.13 ? 32  TRP C CE3   1 
ATOM 2625 C CZ2   . TRP C 3 32  ? 165.017 173.877 178.381 1.00 114.98 ? 32  TRP C CZ2   1 
ATOM 2626 C CZ3   . TRP C 3 32  ? 165.734 175.974 179.335 1.00 116.22 ? 32  TRP C CZ3   1 
ATOM 2627 C CH2   . TRP C 3 32  ? 164.966 175.243 178.425 1.00 114.28 ? 32  TRP C CH2   1 
ATOM 2628 N N     . ARG C 3 33  ? 166.710 172.813 184.706 1.00 94.82  ? 33  ARG C N     1 
ATOM 2629 C CA    . ARG C 3 33  ? 165.534 172.357 185.438 1.00 89.08  ? 33  ARG C CA    1 
ATOM 2630 C C     . ARG C 3 33  ? 164.911 173.490 186.240 1.00 92.84  ? 33  ARG C C     1 
ATOM 2631 O O     . ARG C 3 33  ? 163.691 173.532 186.425 1.00 97.07  ? 33  ARG C O     1 
ATOM 2632 C CB    . ARG C 3 33  ? 165.914 171.204 186.363 1.00 94.54  ? 33  ARG C CB    1 
ATOM 2633 C CG    . ARG C 3 33  ? 166.325 169.940 185.642 1.00 94.50  ? 33  ARG C CG    1 
ATOM 2634 C CD    . ARG C 3 33  ? 166.310 168.748 186.578 1.00 96.96  ? 33  ARG C CD    1 
ATOM 2635 N NE    . ARG C 3 33  ? 167.540 168.643 187.355 1.00 94.11  ? 33  ARG C NE    1 
ATOM 2636 C CZ    . ARG C 3 33  ? 167.643 168.952 188.639 1.00 91.39  ? 33  ARG C CZ    1 
ATOM 2637 N NH1   . ARG C 3 33  ? 166.612 169.423 189.321 1.00 90.60  ? 33  ARG C NH1   1 
ATOM 2638 N NH2   . ARG C 3 33  ? 168.809 168.786 189.255 1.00 97.14  ? 33  ARG C NH2   1 
ATOM 2639 N N     . ALA C 3 34  ? 165.737 174.413 186.734 1.00 93.84  ? 34  ALA C N     1 
ATOM 2640 C CA    . ALA C 3 34  ? 165.223 175.511 187.546 1.00 93.19  ? 34  ALA C CA    1 
ATOM 2641 C C     . ALA C 3 34  ? 164.292 176.406 186.740 1.00 98.78  ? 34  ALA C C     1 
ATOM 2642 O O     . ALA C 3 34  ? 163.233 176.817 187.227 1.00 100.02 ? 34  ALA C O     1 
ATOM 2643 C CB    . ALA C 3 34  ? 166.381 176.321 188.122 1.00 99.79  ? 34  ALA C CB    1 
ATOM 2644 N N     . MET C 3 35  ? 164.673 176.725 185.502 1.00 100.40 ? 35  MET C N     1 
ATOM 2645 C CA    . MET C 3 35  ? 163.848 177.605 184.680 1.00 98.07  ? 35  MET C CA    1 
ATOM 2646 C C     . MET C 3 35  ? 162.512 176.953 184.346 1.00 99.41  ? 35  MET C C     1 
ATOM 2647 O O     . MET C 3 35  ? 161.457 177.592 184.434 1.00 100.96 ? 35  MET C O     1 
ATOM 2648 C CB    . MET C 3 35  ? 164.594 177.983 183.402 1.00 96.03  ? 35  MET C CB    1 
ATOM 2649 C CG    . MET C 3 35  ? 166.092 178.125 183.574 1.00 98.10  ? 35  MET C CG    1 
ATOM 2650 S SD    . MET C 3 35  ? 166.786 179.389 182.495 1.00 109.07 ? 35  MET C SD    1 
ATOM 2651 C CE    . MET C 3 35  ? 166.052 180.865 183.192 1.00 105.70 ? 35  MET C CE    1 
ATOM 2652 N N     . LEU C 3 36  ? 162.538 175.674 183.967 1.00 102.17 ? 36  LEU C N     1 
ATOM 2653 C CA    . LEU C 3 36  ? 161.314 174.995 183.549 1.00 103.44 ? 36  LEU C CA    1 
ATOM 2654 C C     . LEU C 3 36  ? 160.368 174.774 184.721 1.00 108.88 ? 36  LEU C C     1 
ATOM 2655 O O     . LEU C 3 36  ? 159.165 175.043 184.619 1.00 114.28 ? 36  LEU C O     1 
ATOM 2656 C CB    . LEU C 3 36  ? 161.653 173.662 182.882 1.00 103.84 ? 36  LEU C CB    1 
ATOM 2657 C CG    . LEU C 3 36  ? 162.745 173.669 181.816 1.00 105.37 ? 36  LEU C CG    1 
ATOM 2658 C CD1   . LEU C 3 36  ? 162.791 172.338 181.090 1.00 105.45 ? 36  LEU C CD1   1 
ATOM 2659 C CD2   . LEU C 3 36  ? 162.476 174.790 180.833 1.00 107.22 ? 36  LEU C CD2   1 
ATOM 2660 N N     . ALA C 3 37  ? 160.889 174.280 185.839 1.00 109.40 ? 37  ALA C N     1 
ATOM 2661 C CA    . ALA C 3 37  ? 160.041 173.892 186.955 1.00 108.99 ? 37  ALA C CA    1 
ATOM 2662 C C     . ALA C 3 37  ? 159.362 175.105 187.579 1.00 107.24 ? 37  ALA C C     1 
ATOM 2663 O O     . ALA C 3 37  ? 159.945 176.185 187.691 1.00 103.40 ? 37  ALA C O     1 
ATOM 2664 C CB    . ALA C 3 37  ? 160.856 173.150 188.011 1.00 107.78 ? 37  ALA C CB    1 
ATOM 2665 N N     . ARG C 3 38  ? 158.108 174.917 187.975 1.00 113.35 ? 38  ARG C N     1 
ATOM 2666 C CA    . ARG C 3 38  ? 157.347 175.930 188.686 1.00 114.82 ? 38  ARG C CA    1 
ATOM 2667 C C     . ARG C 3 38  ? 157.144 175.477 190.124 1.00 113.89 ? 38  ARG C C     1 
ATOM 2668 O O     . ARG C 3 38  ? 156.832 174.310 190.380 1.00 113.22 ? 38  ARG C O     1 
ATOM 2669 C CB    . ARG C 3 38  ? 155.995 176.191 188.018 1.00 117.72 ? 38  ARG C CB    1 
ATOM 2670 C CG    . ARG C 3 38  ? 155.100 177.148 188.793 1.00 117.54 ? 38  ARG C CG    1 
ATOM 2671 C CD    . ARG C 3 38  ? 153.647 176.699 188.794 1.00 118.24 ? 38  ARG C CD    1 
ATOM 2672 N NE    . ARG C 3 38  ? 153.432 175.512 189.612 1.00 120.57 ? 38  ARG C NE    1 
ATOM 2673 C CZ    . ARG C 3 38  ? 152.251 175.133 190.084 1.00 120.88 ? 38  ARG C CZ    1 
ATOM 2674 N NH1   . ARG C 3 38  ? 151.156 175.837 189.851 1.00 120.93 ? 38  ARG C NH1   1 
ATOM 2675 N NH2   . ARG C 3 38  ? 152.169 174.022 190.809 1.00 118.95 ? 38  ARG C NH2   1 
ATOM 2676 N N     . TYR C 3 39  ? 157.336 176.402 191.058 1.00 95.08  ? 39  TYR C N     1 
ATOM 2677 C CA    . TYR C 3 39  ? 157.336 176.100 192.480 1.00 92.96  ? 39  TYR C CA    1 
ATOM 2678 C C     . TYR C 3 39  ? 156.266 176.909 193.194 1.00 94.75  ? 39  TYR C C     1 
ATOM 2679 O O     . TYR C 3 39  ? 156.098 178.105 192.938 1.00 100.60 ? 39  TYR C O     1 
ATOM 2680 C CB    . TYR C 3 39  ? 158.722 176.372 193.080 1.00 87.92  ? 39  TYR C CB    1 
ATOM 2681 C CG    . TYR C 3 39  ? 158.775 176.483 194.588 1.00 89.47  ? 39  TYR C CG    1 
ATOM 2682 C CD1   . TYR C 3 39  ? 159.191 175.415 195.359 1.00 90.43  ? 39  TYR C CD1   1 
ATOM 2683 C CD2   . TYR C 3 39  ? 158.492 177.682 195.232 1.00 90.51  ? 39  TYR C CD2   1 
ATOM 2684 C CE1   . TYR C 3 39  ? 159.263 175.514 196.725 1.00 91.46  ? 39  TYR C CE1   1 
ATOM 2685 C CE2   . TYR C 3 39  ? 158.563 177.788 196.600 1.00 89.60  ? 39  TYR C CE2   1 
ATOM 2686 C CZ    . TYR C 3 39  ? 158.952 176.701 197.340 1.00 92.75  ? 39  TYR C CZ    1 
ATOM 2687 O OH    . TYR C 3 39  ? 159.031 176.794 198.708 1.00 97.41  ? 39  TYR C OH    1 
ATOM 2688 N N     . VAL C 3 40  ? 155.544 176.244 194.090 1.00 94.68  ? 40  VAL C N     1 
ATOM 2689 C CA    . VAL C 3 40  ? 154.618 176.916 194.994 1.00 96.17  ? 40  VAL C CA    1 
ATOM 2690 C C     . VAL C 3 40  ? 154.865 176.362 196.394 1.00 99.65  ? 40  VAL C C     1 
ATOM 2691 O O     . VAL C 3 40  ? 155.127 175.159 196.549 1.00 93.92  ? 40  VAL C O     1 
ATOM 2692 C CB    . VAL C 3 40  ? 153.160 176.743 194.533 1.00 97.71  ? 40  VAL C CB    1 
ATOM 2693 C CG1   . VAL C 3 40  ? 152.609 175.375 194.915 1.00 99.49  ? 40  VAL C CG1   1 
ATOM 2694 C CG2   . VAL C 3 40  ? 152.282 177.858 195.085 1.00 96.38  ? 40  VAL C CG2   1 
ATOM 2695 N N     . PRO C 3 41  ? 154.852 177.201 197.429 1.00 90.93  ? 41  PRO C N     1 
ATOM 2696 C CA    . PRO C 3 41  ? 155.060 176.693 198.788 1.00 83.68  ? 41  PRO C CA    1 
ATOM 2697 C C     . PRO C 3 41  ? 153.959 175.728 199.200 1.00 89.15  ? 41  PRO C C     1 
ATOM 2698 O O     . PRO C 3 41  ? 152.790 175.894 198.847 1.00 91.30  ? 41  PRO C O     1 
ATOM 2699 C CB    . PRO C 3 41  ? 155.048 177.963 199.648 1.00 82.43  ? 41  PRO C CB    1 
ATOM 2700 C CG    . PRO C 3 41  ? 154.424 179.017 198.791 1.00 86.07  ? 41  PRO C CG    1 
ATOM 2701 C CD    . PRO C 3 41  ? 154.804 178.671 197.394 1.00 86.84  ? 41  PRO C CD    1 
ATOM 2702 N N     . ASN C 3 42  ? 154.349 174.716 199.971 1.00 99.72  ? 42  ASN C N     1 
ATOM 2703 C CA    . ASN C 3 42  ? 153.434 173.663 200.378 1.00 99.03  ? 42  ASN C CA    1 
ATOM 2704 C C     . ASN C 3 42  ? 152.370 174.216 201.323 1.00 94.48  ? 42  ASN C C     1 
ATOM 2705 O O     . ASN C 3 42  ? 152.354 175.399 201.671 1.00 96.64  ? 42  ASN C O     1 
ATOM 2706 C CB    . ASN C 3 42  ? 154.201 172.526 201.048 1.00 90.71  ? 42  ASN C CB    1 
ATOM 2707 C CG    . ASN C 3 42  ? 155.161 171.839 200.106 1.00 91.98  ? 42  ASN C CG    1 
ATOM 2708 O OD1   . ASN C 3 42  ? 155.605 172.426 199.121 1.00 99.72  ? 42  ASN C OD1   1 
ATOM 2709 N ND2   . ASN C 3 42  ? 155.493 170.589 200.404 1.00 80.91  ? 42  ASN C ND2   1 
ATOM 2710 N N     . LYS C 3 43  ? 151.457 173.339 201.738 1.00 98.68  ? 43  LYS C N     1 
ATOM 2711 C CA    . LYS C 3 43  ? 150.507 173.703 202.779 1.00 97.29  ? 43  LYS C CA    1 
ATOM 2712 C C     . LYS C 3 43  ? 151.155 173.766 204.152 1.00 103.28 ? 43  LYS C C     1 
ATOM 2713 O O     . LYS C 3 43  ? 150.537 174.288 205.086 1.00 104.51 ? 43  LYS C O     1 
ATOM 2714 C CB    . LYS C 3 43  ? 149.340 172.717 202.801 1.00 97.14  ? 43  LYS C CB    1 
ATOM 2715 C CG    . LYS C 3 43  ? 148.781 172.391 201.429 1.00 101.29 ? 43  LYS C CG    1 
ATOM 2716 C CD    . LYS C 3 43  ? 147.682 171.349 201.518 1.00 107.57 ? 43  LYS C CD    1 
ATOM 2717 C CE    . LYS C 3 43  ? 146.501 171.719 200.640 1.00 104.76 ? 43  LYS C CE    1 
ATOM 2718 N NZ    . LYS C 3 43  ? 145.826 172.956 201.119 1.00 102.79 ? 43  LYS C NZ    1 
ATOM 2719 N N     . GLY C 3 44  ? 152.374 173.248 204.298 1.00 96.28  ? 44  GLY C N     1 
ATOM 2720 C CA    . GLY C 3 44  ? 153.108 173.371 205.541 1.00 86.86  ? 44  GLY C CA    1 
ATOM 2721 C C     . GLY C 3 44  ? 153.788 174.702 205.742 1.00 84.60  ? 44  GLY C C     1 
ATOM 2722 O O     . GLY C 3 44  ? 154.322 174.954 206.825 1.00 90.51  ? 44  GLY C O     1 
ATOM 2723 N N     . VAL C 3 45  ? 153.778 175.560 204.728 1.00 73.01  ? 45  VAL C N     1 
ATOM 2724 C CA    . VAL C 3 45  ? 154.358 176.893 204.835 1.00 73.25  ? 45  VAL C CA    1 
ATOM 2725 C C     . VAL C 3 45  ? 153.333 177.792 205.516 1.00 78.28  ? 45  VAL C C     1 
ATOM 2726 O O     . VAL C 3 45  ? 152.288 178.104 204.942 1.00 88.31  ? 45  VAL C O     1 
ATOM 2727 C CB    . VAL C 3 45  ? 154.755 177.441 203.463 1.00 78.73  ? 45  VAL C CB    1 
ATOM 2728 C CG1   . VAL C 3 45  ? 155.290 178.851 203.594 1.00 83.39  ? 45  VAL C CG1   1 
ATOM 2729 C CG2   . VAL C 3 45  ? 155.782 176.531 202.819 1.00 84.54  ? 45  VAL C CG2   1 
ATOM 2730 N N     . ILE C 3 46  ? 153.632 178.213 206.743 1.00 78.57  ? 46  ILE C N     1 
ATOM 2731 C CA    . ILE C 3 46  ? 152.684 178.940 207.572 1.00 84.88  ? 46  ILE C CA    1 
ATOM 2732 C C     . ILE C 3 46  ? 153.335 180.230 208.046 1.00 90.17  ? 46  ILE C C     1 
ATOM 2733 O O     . ILE C 3 46  ? 154.558 180.378 208.036 1.00 95.74  ? 46  ILE C O     1 
ATOM 2734 C CB    . ILE C 3 46  ? 152.218 178.104 208.783 1.00 91.17  ? 46  ILE C CB    1 
ATOM 2735 C CG1   . ILE C 3 46  ? 152.119 176.626 208.407 1.00 93.18  ? 46  ILE C CG1   1 
ATOM 2736 C CG2   . ILE C 3 46  ? 150.868 178.591 209.282 1.00 93.17  ? 46  ILE C CG2   1 
ATOM 2737 C CD1   . ILE C 3 46  ? 152.098 175.692 209.596 1.00 92.14  ? 46  ILE C CD1   1 
ATOM 2738 N N     . GLY C 3 47  ? 152.495 181.174 208.455 1.00 108.35 ? 47  GLY C N     1 
ATOM 2739 C CA    . GLY C 3 47  ? 152.960 182.389 209.087 1.00 106.97 ? 47  GLY C CA    1 
ATOM 2740 C C     . GLY C 3 47  ? 153.353 183.465 208.093 1.00 111.52 ? 47  GLY C C     1 
ATOM 2741 O O     . GLY C 3 47  ? 153.473 183.245 206.887 1.00 112.92 ? 47  GLY C O     1 
ATOM 2742 N N     . ASP C 3 48  ? 153.560 184.660 208.627 1.00 117.17 ? 48  ASP C N     1 
ATOM 2743 C CA    . ASP C 3 48  ? 153.971 185.793 207.811 1.00 118.33 ? 48  ASP C CA    1 
ATOM 2744 C C     . ASP C 3 48  ? 155.404 185.576 207.345 1.00 115.94 ? 48  ASP C C     1 
ATOM 2745 O O     . ASP C 3 48  ? 156.296 185.397 208.183 1.00 116.74 ? 48  ASP C O     1 
ATOM 2746 C CB    . ASP C 3 48  ? 153.847 187.086 208.614 1.00 116.79 ? 48  ASP C CB    1 
ATOM 2747 C CG    . ASP C 3 48  ? 154.429 188.285 207.894 1.00 118.48 ? 48  ASP C CG    1 
ATOM 2748 O OD1   . ASP C 3 48  ? 154.277 188.376 206.659 1.00 118.64 ? 48  ASP C OD1   1 
ATOM 2749 O OD2   . ASP C 3 48  ? 155.030 189.148 208.565 1.00 117.07 ? 48  ASP C OD2   1 
ATOM 2750 N N     . PRO C 3 49  ? 155.671 185.573 206.038 1.00 98.78  ? 49  PRO C N     1 
ATOM 2751 C CA    . PRO C 3 49  ? 157.034 185.278 205.568 1.00 95.46  ? 49  PRO C CA    1 
ATOM 2752 C C     . PRO C 3 49  ? 158.065 186.300 205.997 1.00 98.79  ? 49  PRO C C     1 
ATOM 2753 O O     . PRO C 3 49  ? 159.264 185.995 205.969 1.00 100.83 ? 49  PRO C O     1 
ATOM 2754 C CB    . PRO C 3 49  ? 156.879 185.251 204.042 1.00 100.10 ? 49  PRO C CB    1 
ATOM 2755 C CG    . PRO C 3 49  ? 155.660 186.071 203.775 1.00 99.46  ? 49  PRO C CG    1 
ATOM 2756 C CD    . PRO C 3 49  ? 154.740 185.798 204.922 1.00 101.41 ? 49  PRO C CD    1 
ATOM 2757 N N     . LEU C 3 50  ? 157.643 187.504 206.388 1.00 103.61 ? 50  LEU C N     1 
ATOM 2758 C CA    . LEU C 3 50  ? 158.599 188.533 206.779 1.00 104.59 ? 50  LEU C CA    1 
ATOM 2759 C C     . LEU C 3 50  ? 159.364 188.135 208.034 1.00 101.06 ? 50  LEU C C     1 
ATOM 2760 O O     . LEU C 3 50  ? 160.543 188.473 208.183 1.00 104.82 ? 50  LEU C O     1 
ATOM 2761 C CB    . LEU C 3 50  ? 157.876 189.860 206.997 1.00 103.43 ? 50  LEU C CB    1 
ATOM 2762 C CG    . LEU C 3 50  ? 157.038 190.341 205.816 1.00 101.29 ? 50  LEU C CG    1 
ATOM 2763 C CD1   . LEU C 3 50  ? 156.374 191.670 206.138 1.00 100.67 ? 50  LEU C CD1   1 
ATOM 2764 C CD2   . LEU C 3 50  ? 157.898 190.449 204.568 1.00 100.97 ? 50  LEU C CD2   1 
ATOM 2765 N N     . LEU C 3 51  ? 158.714 187.420 208.949 1.00 93.45  ? 51  LEU C N     1 
ATOM 2766 C CA    . LEU C 3 51  ? 159.283 187.130 210.256 1.00 86.99  ? 51  LEU C CA    1 
ATOM 2767 C C     . LEU C 3 51  ? 159.879 185.734 210.355 1.00 84.29  ? 51  LEU C C     1 
ATOM 2768 O O     . LEU C 3 51  ? 160.271 185.321 211.449 1.00 95.32  ? 51  LEU C O     1 
ATOM 2769 C CB    . LEU C 3 51  ? 158.223 187.318 211.340 1.00 91.34  ? 51  LEU C CB    1 
ATOM 2770 C CG    . LEU C 3 51  ? 157.322 188.541 211.176 1.00 95.37  ? 51  LEU C CG    1 
ATOM 2771 C CD1   . LEU C 3 51  ? 156.300 188.602 212.294 1.00 96.87  ? 51  LEU C CD1   1 
ATOM 2772 C CD2   . LEU C 3 51  ? 158.147 189.815 211.136 1.00 93.58  ? 51  LEU C CD2   1 
ATOM 2773 N N     . THR C 3 52  ? 159.963 185.000 209.253 1.00 77.70  ? 52  THR C N     1 
ATOM 2774 C CA    . THR C 3 52  ? 160.498 183.643 209.280 1.00 79.45  ? 52  THR C CA    1 
ATOM 2775 C C     . THR C 3 52  ? 161.994 183.701 209.008 1.00 76.59  ? 52  THR C C     1 
ATOM 2776 O O     . THR C 3 52  ? 162.418 183.948 207.876 1.00 83.60  ? 52  THR C O     1 
ATOM 2777 C CB    . THR C 3 52  ? 159.793 182.755 208.261 1.00 87.21  ? 52  THR C CB    1 
ATOM 2778 O OG1   . THR C 3 52  ? 158.411 183.122 208.181 1.00 95.31  ? 52  THR C OG1   1 
ATOM 2779 C CG2   . THR C 3 52  ? 159.906 181.293 208.667 1.00 85.80  ? 52  THR C CG2   1 
ATOM 2780 N N     . LEU C 3 53  ? 162.792 183.469 210.043 1.00 58.76  ? 53  LEU C N     1 
ATOM 2781 C CA    . LEU C 3 53  ? 164.245 183.470 209.912 1.00 65.18  ? 53  LEU C CA    1 
ATOM 2782 C C     . LEU C 3 53  ? 164.691 182.051 209.595 1.00 61.55  ? 53  LEU C C     1 
ATOM 2783 O O     . LEU C 3 53  ? 164.855 181.214 210.480 1.00 62.43  ? 53  LEU C O     1 
ATOM 2784 C CB    . LEU C 3 53  ? 164.901 183.992 211.180 1.00 65.87  ? 53  LEU C CB    1 
ATOM 2785 C CG    . LEU C 3 53  ? 166.408 184.192 211.061 1.00 59.29  ? 53  LEU C CG    1 
ATOM 2786 C CD1   . LEU C 3 53  ? 166.725 185.662 210.887 1.00 62.02  ? 53  LEU C CD1   1 
ATOM 2787 C CD2   . LEU C 3 53  ? 167.115 183.617 212.269 1.00 66.34  ? 53  LEU C CD2   1 
ATOM 2788 N N     . PHE C 3 54  ? 164.896 181.778 208.315 1.00 52.21  ? 54  PHE C N     1 
ATOM 2789 C CA    . PHE C 3 54  ? 165.327 180.453 207.900 1.00 53.39  ? 54  PHE C CA    1 
ATOM 2790 C C     . PHE C 3 54  ? 166.772 180.221 208.308 1.00 60.95  ? 54  PHE C C     1 
ATOM 2791 O O     . PHE C 3 54  ? 167.665 180.968 207.905 1.00 82.89  ? 54  PHE C O     1 
ATOM 2792 C CB    . PHE C 3 54  ? 165.167 180.310 206.390 1.00 66.42  ? 54  PHE C CB    1 
ATOM 2793 C CG    . PHE C 3 54  ? 166.059 179.279 205.775 1.00 56.16  ? 54  PHE C CG    1 
ATOM 2794 C CD1   . PHE C 3 54  ? 165.747 177.939 205.860 1.00 63.88  ? 54  PHE C CD1   1 
ATOM 2795 C CD2   . PHE C 3 54  ? 167.190 179.651 205.082 1.00 55.97  ? 54  PHE C CD2   1 
ATOM 2796 C CE1   . PHE C 3 54  ? 166.555 176.991 205.285 1.00 57.70  ? 54  PHE C CE1   1 
ATOM 2797 C CE2   . PHE C 3 54  ? 168.001 178.706 204.507 1.00 65.60  ? 54  PHE C CE2   1 
ATOM 2798 C CZ    . PHE C 3 54  ? 167.682 177.375 204.608 1.00 59.61  ? 54  PHE C CZ    1 
ATOM 2799 N N     . VAL C 3 55  ? 167.006 179.185 209.108 1.00 55.90  ? 55  VAL C N     1 
ATOM 2800 C CA    . VAL C 3 55  ? 168.350 178.810 209.527 1.00 52.61  ? 55  VAL C CA    1 
ATOM 2801 C C     . VAL C 3 55  ? 168.672 177.453 208.924 1.00 49.51  ? 55  VAL C C     1 
ATOM 2802 O O     . VAL C 3 55  ? 167.778 176.627 208.718 1.00 62.38  ? 55  VAL C O     1 
ATOM 2803 C CB    . VAL C 3 55  ? 168.499 178.781 211.062 1.00 51.03  ? 55  VAL C CB    1 
ATOM 2804 C CG1   . VAL C 3 55  ? 167.810 179.982 211.685 1.00 54.38  ? 55  VAL C CG1   1 
ATOM 2805 C CG2   . VAL C 3 55  ? 167.977 177.486 211.643 1.00 62.52  ? 55  VAL C CG2   1 
ATOM 2806 N N     . ALA C 3 56  ? 169.945 177.230 208.623 1.00 46.98  ? 56  ALA C N     1 
ATOM 2807 C CA    . ALA C 3 56  ? 170.377 176.010 207.962 1.00 59.47  ? 56  ALA C CA    1 
ATOM 2808 C C     . ALA C 3 56  ? 171.703 175.553 208.550 1.00 69.03  ? 56  ALA C C     1 
ATOM 2809 O O     . ALA C 3 56  ? 172.251 176.172 209.464 1.00 80.35  ? 56  ALA C O     1 
ATOM 2810 C CB    . ALA C 3 56  ? 170.497 176.212 206.448 1.00 67.20  ? 56  ALA C CB    1 
ATOM 2811 N N     . ARG C 3 57  ? 172.214 174.448 208.012 1.00 80.88  ? 57  ARG C N     1 
ATOM 2812 C CA    . ARG C 3 57  ? 173.480 173.867 208.448 1.00 78.76  ? 57  ARG C CA    1 
ATOM 2813 C C     . ARG C 3 57  ? 173.482 173.568 209.943 1.00 80.22  ? 57  ARG C C     1 
ATOM 2814 O O     . ARG C 3 57  ? 174.510 173.692 210.609 1.00 87.05  ? 57  ARG C O     1 
ATOM 2815 C CB    . ARG C 3 57  ? 174.660 174.765 208.073 1.00 78.80  ? 57  ARG C CB    1 
ATOM 2816 C CG    . ARG C 3 57  ? 174.814 174.949 206.574 1.00 78.26  ? 57  ARG C CG    1 
ATOM 2817 C CD    . ARG C 3 57  ? 176.051 175.751 206.223 1.00 79.25  ? 57  ARG C CD    1 
ATOM 2818 N NE    . ARG C 3 57  ? 176.254 175.818 204.781 1.00 81.45  ? 57  ARG C NE    1 
ATOM 2819 C CZ    . ARG C 3 57  ? 176.589 176.918 204.122 1.00 88.84  ? 57  ARG C CZ    1 
ATOM 2820 N NH1   . ARG C 3 57  ? 176.763 178.071 204.745 1.00 89.47  ? 57  ARG C NH1   1 
ATOM 2821 N NH2   . ARG C 3 57  ? 176.745 176.861 202.803 1.00 82.96  ? 57  ARG C NH2   1 
ATOM 2822 N N     . LEU C 3 58  ? 172.329 173.178 210.479 1.00 74.38  ? 58  LEU C N     1 
ATOM 2823 C CA    . LEU C 3 58  ? 172.259 172.714 211.853 1.00 72.54  ? 58  LEU C CA    1 
ATOM 2824 C C     . LEU C 3 58  ? 172.769 171.281 211.944 1.00 67.16  ? 58  LEU C C     1 
ATOM 2825 O O     . LEU C 3 58  ? 172.909 170.574 210.943 1.00 73.12  ? 58  LEU C O     1 
ATOM 2826 C CB    . LEU C 3 58  ? 170.828 172.785 212.374 1.00 62.94  ? 58  LEU C CB    1 
ATOM 2827 C CG    . LEU C 3 58  ? 170.050 174.061 212.079 1.00 64.29  ? 58  LEU C CG    1 
ATOM 2828 C CD1   . LEU C 3 58  ? 168.603 173.873 212.452 1.00 66.69  ? 58  LEU C CD1   1 
ATOM 2829 C CD2   . LEU C 3 58  ? 170.638 175.233 212.828 1.00 69.20  ? 58  LEU C CD2   1 
ATOM 2830 N N     . ASN C 3 59  ? 173.054 170.849 213.166 1.00 80.38  ? 59  ASN C N     1 
ATOM 2831 C CA    . ASN C 3 59  ? 173.377 169.452 213.395 1.00 92.17  ? 59  ASN C CA    1 
ATOM 2832 C C     . ASN C 3 59  ? 172.103 168.622 213.333 1.00 96.58  ? 59  ASN C C     1 
ATOM 2833 O O     . ASN C 3 59  ? 171.042 169.052 213.793 1.00 101.58 ? 59  ASN C O     1 
ATOM 2834 C CB    . ASN C 3 59  ? 174.064 169.265 214.746 1.00 95.38  ? 59  ASN C CB    1 
ATOM 2835 C CG    . ASN C 3 59  ? 174.864 167.981 214.818 1.00 94.40  ? 59  ASN C CG    1 
ATOM 2836 O OD1   . ASN C 3 59  ? 174.553 167.003 214.141 1.00 97.07  ? 59  ASN C OD1   1 
ATOM 2837 N ND2   . ASN C 3 59  ? 175.898 167.976 215.647 1.00 91.74  ? 59  ASN C ND2   1 
ATOM 2838 N N     . LEU C 3 60  ? 172.208 167.426 212.752 1.00 93.70  ? 60  LEU C N     1 
ATOM 2839 C CA    . LEU C 3 60  ? 171.041 166.560 212.648 1.00 89.12  ? 60  LEU C CA    1 
ATOM 2840 C C     . LEU C 3 60  ? 170.538 166.103 214.010 1.00 94.05  ? 60  LEU C C     1 
ATOM 2841 O O     . LEU C 3 60  ? 169.383 165.680 214.122 1.00 101.55 ? 60  LEU C O     1 
ATOM 2842 C CB    . LEU C 3 60  ? 171.361 165.353 211.770 1.00 88.77  ? 60  LEU C CB    1 
ATOM 2843 C CG    . LEU C 3 60  ? 171.836 165.696 210.360 1.00 87.76  ? 60  LEU C CG    1 
ATOM 2844 C CD1   . LEU C 3 60  ? 171.880 164.451 209.496 1.00 91.61  ? 60  LEU C CD1   1 
ATOM 2845 C CD2   . LEU C 3 60  ? 170.937 166.751 209.739 1.00 85.23  ? 60  LEU C CD2   1 
ATOM 2846 N N     . GLN C 3 61  ? 171.374 166.172 215.043 1.00 94.68  ? 61  GLN C N     1 
ATOM 2847 C CA    . GLN C 3 61  ? 170.941 165.830 216.389 1.00 93.00  ? 61  GLN C CA    1 
ATOM 2848 C C     . GLN C 3 61  ? 170.355 167.015 217.143 1.00 93.01  ? 61  GLN C C     1 
ATOM 2849 O O     . GLN C 3 61  ? 169.968 166.855 218.304 1.00 96.96  ? 61  GLN C O     1 
ATOM 2850 C CB    . GLN C 3 61  ? 172.104 165.244 217.194 1.00 96.18  ? 61  GLN C CB    1 
ATOM 2851 C CG    . GLN C 3 61  ? 172.437 163.771 216.931 1.00 98.04  ? 61  GLN C CG    1 
ATOM 2852 C CD    . GLN C 3 61  ? 172.446 163.377 215.463 1.00 101.31 ? 61  GLN C CD    1 
ATOM 2853 O OE1   . GLN C 3 61  ? 172.754 164.183 214.585 1.00 102.57 ? 61  GLN C OE1   1 
ATOM 2854 N NE2   . GLN C 3 61  ? 172.113 162.120 215.193 1.00 100.45 ? 61  GLN C NE2   1 
ATOM 2855 N N     . THR C 3 62  ? 170.292 168.192 216.530 1.00 76.97  ? 62  THR C N     1 
ATOM 2856 C CA    . THR C 3 62  ? 169.713 169.345 217.204 1.00 78.34  ? 62  THR C CA    1 
ATOM 2857 C C     . THR C 3 62  ? 168.205 169.183 217.334 1.00 77.51  ? 62  THR C C     1 
ATOM 2858 O O     . THR C 3 62  ? 167.516 168.831 216.374 1.00 79.14  ? 62  THR C O     1 
ATOM 2859 C CB    . THR C 3 62  ? 170.030 170.629 216.442 1.00 81.81  ? 62  THR C CB    1 
ATOM 2860 O OG1   . THR C 3 62  ? 171.400 170.614 216.029 1.00 87.21  ? 62  THR C OG1   1 
ATOM 2861 C CG2   . THR C 3 62  ? 169.788 171.839 217.323 1.00 79.05  ? 62  THR C CG2   1 
ATOM 2862 N N     . LYS C 3 63  ? 167.693 169.446 218.528 1.00 79.65  ? 63  LYS C N     1 
ATOM 2863 C CA    . LYS C 3 63  ? 166.268 169.367 218.798 1.00 79.09  ? 63  LYS C CA    1 
ATOM 2864 C C     . LYS C 3 63  ? 165.644 170.752 218.717 1.00 81.77  ? 63  LYS C C     1 
ATOM 2865 O O     . LYS C 3 63  ? 166.311 171.772 218.890 1.00 86.94  ? 63  LYS C O     1 
ATOM 2866 C CB    . LYS C 3 63  ? 166.006 168.750 220.172 1.00 81.79  ? 63  LYS C CB    1 
ATOM 2867 C CG    . LYS C 3 63  ? 166.733 167.438 220.402 1.00 84.40  ? 63  LYS C CG    1 
ATOM 2868 C CD    . LYS C 3 63  ? 166.256 166.366 219.439 1.00 88.42  ? 63  LYS C CD    1 
ATOM 2869 C CE    . LYS C 3 63  ? 166.977 165.051 219.677 1.00 83.01  ? 63  LYS C CE    1 
ATOM 2870 N NZ    . LYS C 3 63  ? 166.462 163.972 218.794 1.00 81.14  ? 63  LYS C NZ    1 
ATOM 2871 N N     . GLU C 3 64  ? 164.339 170.774 218.452 1.00 94.52  ? 64  GLU C N     1 
ATOM 2872 C CA    . GLU C 3 64  ? 163.662 172.045 218.228 1.00 95.90  ? 64  GLU C CA    1 
ATOM 2873 C C     . GLU C 3 64  ? 163.607 172.887 219.495 1.00 98.72  ? 64  GLU C C     1 
ATOM 2874 O O     . GLU C 3 64  ? 163.437 174.107 219.418 1.00 101.41 ? 64  GLU C O     1 
ATOM 2875 C CB    . GLU C 3 64  ? 162.262 171.791 217.669 1.00 97.35  ? 64  GLU C CB    1 
ATOM 2876 C CG    . GLU C 3 64  ? 161.128 171.997 218.646 1.00 102.86 ? 64  GLU C CG    1 
ATOM 2877 C CD    . GLU C 3 64  ? 159.772 171.944 217.969 1.00 111.27 ? 64  GLU C CD    1 
ATOM 2878 O OE1   . GLU C 3 64  ? 159.649 172.448 216.834 1.00 104.47 ? 64  GLU C OE1   1 
ATOM 2879 O OE2   . GLU C 3 64  ? 158.825 171.399 218.572 1.00 113.12 ? 64  GLU C OE2   1 
ATOM 2880 N N     . ASP C 3 65  ? 163.751 172.262 220.665 1.00 95.58  ? 65  ASP C N     1 
ATOM 2881 C CA    . ASP C 3 65  ? 163.783 173.025 221.909 1.00 97.88  ? 65  ASP C CA    1 
ATOM 2882 C C     . ASP C 3 65  ? 165.077 173.817 222.043 1.00 98.44  ? 65  ASP C C     1 
ATOM 2883 O O     . ASP C 3 65  ? 165.064 174.975 222.477 1.00 99.06  ? 65  ASP C O     1 
ATOM 2884 C CB    . ASP C 3 65  ? 163.568 172.083 223.100 1.00 103.10 ? 65  ASP C CB    1 
ATOM 2885 C CG    . ASP C 3 65  ? 164.739 171.131 223.340 1.00 102.26 ? 65  ASP C CG    1 
ATOM 2886 O OD1   . ASP C 3 65  ? 164.479 169.919 223.495 1.00 103.64 ? 65  ASP C OD1   1 
ATOM 2887 O OD2   . ASP C 3 65  ? 165.905 171.571 223.409 1.00 99.49  ? 65  ASP C OD2   1 
ATOM 2888 N N     . LYS C 3 66  ? 166.207 173.206 221.677 1.00 89.86  ? 66  LYS C N     1 
ATOM 2889 C CA    . LYS C 3 66  ? 167.487 173.902 221.748 1.00 87.99  ? 66  LYS C CA    1 
ATOM 2890 C C     . LYS C 3 66  ? 167.503 175.104 220.818 1.00 83.57  ? 66  LYS C C     1 
ATOM 2891 O O     . LYS C 3 66  ? 168.027 176.166 221.172 1.00 87.31  ? 66  LYS C O     1 
ATOM 2892 C CB    . LYS C 3 66  ? 168.626 172.943 221.405 1.00 89.21  ? 66  LYS C CB    1 
ATOM 2893 C CG    . LYS C 3 66  ? 169.960 173.622 221.166 1.00 85.23  ? 66  LYS C CG    1 
ATOM 2894 C CD    . LYS C 3 66  ? 171.116 172.650 221.337 1.00 86.57  ? 66  LYS C CD    1 
ATOM 2895 C CE    . LYS C 3 66  ? 172.452 173.375 221.348 1.00 88.78  ? 66  LYS C CE    1 
ATOM 2896 N NZ    . LYS C 3 66  ? 173.554 172.516 221.859 1.00 92.26  ? 66  LYS C NZ    1 
ATOM 2897 N N     . LEU C 3 67  ? 166.929 174.957 219.625 1.00 75.69  ? 67  LEU C N     1 
ATOM 2898 C CA    . LEU C 3 67  ? 166.813 176.093 218.721 1.00 81.92  ? 67  LEU C CA    1 
ATOM 2899 C C     . LEU C 3 67  ? 165.987 177.203 219.349 1.00 83.90  ? 67  LEU C C     1 
ATOM 2900 O O     . LEU C 3 67  ? 166.336 178.383 219.243 1.00 90.75  ? 67  LEU C O     1 
ATOM 2901 C CB    . LEU C 3 67  ? 166.196 175.651 217.400 1.00 80.68  ? 67  LEU C CB    1 
ATOM 2902 C CG    . LEU C 3 67  ? 167.092 174.764 216.547 1.00 77.70  ? 67  LEU C CG    1 
ATOM 2903 C CD1   . LEU C 3 67  ? 166.385 174.428 215.260 1.00 80.68  ? 67  LEU C CD1   1 
ATOM 2904 C CD2   . LEU C 3 67  ? 168.400 175.465 216.274 1.00 75.40  ? 67  LEU C CD2   1 
ATOM 2905 N N     . LYS C 3 68  ? 164.886 176.849 220.009 1.00 81.78  ? 68  LYS C N     1 
ATOM 2906 C CA    . LYS C 3 68  ? 164.137 177.855 220.749 1.00 88.16  ? 68  LYS C CA    1 
ATOM 2907 C C     . LYS C 3 68  ? 164.975 178.423 221.884 1.00 93.44  ? 68  LYS C C     1 
ATOM 2908 O O     . LYS C 3 68  ? 164.893 179.617 222.191 1.00 95.87  ? 68  LYS C O     1 
ATOM 2909 C CB    . LYS C 3 68  ? 162.836 177.260 221.287 1.00 91.07  ? 68  LYS C CB    1 
ATOM 2910 C CG    . LYS C 3 68  ? 161.922 178.278 221.953 1.00 88.86  ? 68  LYS C CG    1 
ATOM 2911 C CD    . LYS C 3 68  ? 160.542 177.697 222.209 1.00 89.70  ? 68  LYS C CD    1 
ATOM 2912 C CE    . LYS C 3 68  ? 159.792 177.455 220.912 1.00 89.54  ? 68  LYS C CE    1 
ATOM 2913 N NZ    . LYS C 3 68  ? 158.831 176.324 221.033 1.00 88.34  ? 68  LYS C NZ    1 
ATOM 2914 N N     . GLU C 3 69  ? 165.792 177.578 222.516 1.00 96.46  ? 69  GLU C N     1 
ATOM 2915 C CA    . GLU C 3 69  ? 166.583 178.025 223.657 1.00 93.99  ? 69  GLU C CA    1 
ATOM 2916 C C     . GLU C 3 69  ? 167.611 179.072 223.246 1.00 98.33  ? 69  GLU C C     1 
ATOM 2917 O O     . GLU C 3 69  ? 167.777 180.094 223.921 1.00 104.89 ? 69  GLU C O     1 
ATOM 2918 C CB    . GLU C 3 69  ? 167.267 176.831 224.318 1.00 94.14  ? 69  GLU C CB    1 
ATOM 2919 C CG    . GLU C 3 69  ? 168.391 177.220 225.255 1.00 98.37  ? 69  GLU C CG    1 
ATOM 2920 C CD    . GLU C 3 69  ? 167.920 178.126 226.375 1.00 101.95 ? 69  GLU C CD    1 
ATOM 2921 O OE1   . GLU C 3 69  ? 166.819 177.884 226.912 1.00 99.32  ? 69  GLU C OE1   1 
ATOM 2922 O OE2   . GLU C 3 69  ? 168.647 179.083 226.713 1.00 102.30 ? 69  GLU C OE2   1 
ATOM 2923 N N     . VAL C 3 70  ? 168.313 178.838 222.137 1.00 90.96  ? 70  VAL C N     1 
ATOM 2924 C CA    . VAL C 3 70  ? 169.374 179.755 221.740 1.00 87.91  ? 70  VAL C CA    1 
ATOM 2925 C C     . VAL C 3 70  ? 168.853 180.930 220.928 1.00 86.44  ? 70  VAL C C     1 
ATOM 2926 O O     . VAL C 3 70  ? 169.521 181.967 220.863 1.00 88.05  ? 70  VAL C O     1 
ATOM 2927 C CB    . VAL C 3 70  ? 170.466 179.029 220.941 1.00 84.30  ? 70  VAL C CB    1 
ATOM 2928 C CG1   . VAL C 3 70  ? 170.898 177.769 221.665 1.00 87.99  ? 70  VAL C CG1   1 
ATOM 2929 C CG2   . VAL C 3 70  ? 169.973 178.706 219.553 1.00 83.77  ? 70  VAL C CG2   1 
ATOM 2930 N N     . PHE C 3 71  ? 167.687 180.803 220.303 1.00 77.96  ? 71  PHE C N     1 
ATOM 2931 C CA    . PHE C 3 71  ? 167.136 181.877 219.495 1.00 75.15  ? 71  PHE C CA    1 
ATOM 2932 C C     . PHE C 3 71  ? 166.150 182.741 220.259 1.00 80.50  ? 71  PHE C C     1 
ATOM 2933 O O     . PHE C 3 71  ? 165.618 183.698 219.691 1.00 82.68  ? 71  PHE C O     1 
ATOM 2934 C CB    . PHE C 3 71  ? 166.468 181.309 218.243 1.00 75.90  ? 71  PHE C CB    1 
ATOM 2935 C CG    . PHE C 3 71  ? 167.426 181.033 217.127 1.00 76.72  ? 71  PHE C CG    1 
ATOM 2936 C CD1   . PHE C 3 71  ? 167.850 182.050 216.296 1.00 80.25  ? 71  PHE C CD1   1 
ATOM 2937 C CD2   . PHE C 3 71  ? 167.909 179.758 216.915 1.00 76.31  ? 71  PHE C CD2   1 
ATOM 2938 C CE1   . PHE C 3 71  ? 168.734 181.799 215.275 1.00 74.45  ? 71  PHE C CE1   1 
ATOM 2939 C CE2   . PHE C 3 71  ? 168.793 179.502 215.897 1.00 77.41  ? 71  PHE C CE2   1 
ATOM 2940 C CZ    . PHE C 3 71  ? 169.206 180.523 215.075 1.00 73.91  ? 71  PHE C CZ    1 
ATOM 2941 N N     . SER C 3 72  ? 165.890 182.429 221.527 1.00 81.85  ? 72  SER C N     1 
ATOM 2942 C CA    . SER C 3 72  ? 165.043 183.284 222.344 1.00 84.62  ? 72  SER C CA    1 
ATOM 2943 C C     . SER C 3 72  ? 165.780 184.515 222.849 1.00 86.29  ? 72  SER C C     1 
ATOM 2944 O O     . SER C 3 72  ? 165.134 185.496 223.229 1.00 87.74  ? 72  SER C O     1 
ATOM 2945 C CB    . SER C 3 72  ? 164.489 182.496 223.529 1.00 90.56  ? 72  SER C CB    1 
ATOM 2946 O OG    . SER C 3 72  ? 163.769 181.359 223.090 1.00 91.72  ? 72  SER C OG    1 
ATOM 2947 N N     . ARG C 3 73  ? 167.114 184.487 222.850 1.00 92.88  ? 73  ARG C N     1 
ATOM 2948 C CA    . ARG C 3 73  ? 167.888 185.622 223.336 1.00 96.78  ? 73  ARG C CA    1 
ATOM 2949 C C     . ARG C 3 73  ? 167.693 186.859 222.473 1.00 96.50  ? 73  ARG C C     1 
ATOM 2950 O O     . ARG C 3 73  ? 167.937 187.974 222.943 1.00 99.11  ? 73  ARG C O     1 
ATOM 2951 C CB    . ARG C 3 73  ? 169.369 185.251 223.399 1.00 96.84  ? 73  ARG C CB    1 
ATOM 2952 C CG    . ARG C 3 73  ? 169.984 184.977 222.046 1.00 93.31  ? 73  ARG C CG    1 
ATOM 2953 C CD    . ARG C 3 73  ? 171.350 184.329 222.153 1.00 91.23  ? 73  ARG C CD    1 
ATOM 2954 N NE    . ARG C 3 73  ? 171.289 183.040 222.829 1.00 100.68 ? 73  ARG C NE    1 
ATOM 2955 C CZ    . ARG C 3 73  ? 172.347 182.299 223.128 1.00 101.84 ? 73  ARG C CZ    1 
ATOM 2956 N NH1   . ARG C 3 73  ? 173.571 182.679 222.803 1.00 97.83  ? 73  ARG C NH1   1 
ATOM 2957 N NH2   . ARG C 3 73  ? 172.172 181.145 223.766 1.00 101.77 ? 73  ARG C NH2   1 
ATOM 2958 N N     . TYR C 3 74  ? 167.257 186.687 221.230 1.00 94.61  ? 74  TYR C N     1 
ATOM 2959 C CA    . TYR C 3 74  ? 166.937 187.799 220.347 1.00 94.65  ? 74  TYR C CA    1 
ATOM 2960 C C     . TYR C 3 74  ? 165.531 188.333 220.565 1.00 102.33 ? 74  TYR C C     1 
ATOM 2961 O O     . TYR C 3 74  ? 165.144 189.305 219.910 1.00 101.99 ? 74  TYR C O     1 
ATOM 2962 C CB    . TYR C 3 74  ? 167.105 187.376 218.886 1.00 93.03  ? 74  TYR C CB    1 
ATOM 2963 C CG    . TYR C 3 74  ? 168.392 186.640 218.599 1.00 94.34  ? 74  TYR C CG    1 
ATOM 2964 C CD1   . TYR C 3 74  ? 168.457 185.686 217.598 1.00 98.21  ? 74  TYR C CD1   1 
ATOM 2965 C CD2   . TYR C 3 74  ? 169.559 186.952 219.277 1.00 98.31  ? 74  TYR C CD2   1 
ATOM 2966 C CE1   . TYR C 3 74  ? 169.631 185.024 217.321 1.00 100.23 ? 74  TYR C CE1   1 
ATOM 2967 C CE2   . TYR C 3 74  ? 170.738 186.297 219.004 1.00 101.87 ? 74  TYR C CE2   1 
ATOM 2968 C CZ    . TYR C 3 74  ? 170.768 185.336 218.027 1.00 102.00 ? 74  TYR C CZ    1 
ATOM 2969 O OH    . TYR C 3 74  ? 171.946 184.685 217.753 1.00 104.01 ? 74  TYR C OH    1 
ATOM 2970 N N     . GLY C 3 75  ? 164.765 187.727 221.463 1.00 112.68 ? 75  GLY C N     1 
ATOM 2971 C CA    . GLY C 3 75  ? 163.424 188.165 221.773 1.00 112.15 ? 75  GLY C CA    1 
ATOM 2972 C C     . GLY C 3 75  ? 162.457 187.004 221.820 1.00 113.28 ? 75  GLY C C     1 
ATOM 2973 O O     . GLY C 3 75  ? 162.822 185.840 221.664 1.00 112.87 ? 75  GLY C O     1 
ATOM 2974 N N     . ASP C 3 76  ? 161.192 187.345 222.044 1.00 112.41 ? 76  ASP C N     1 
ATOM 2975 C CA    . ASP C 3 76  ? 160.143 186.338 222.074 1.00 109.49 ? 76  ASP C CA    1 
ATOM 2976 C C     . ASP C 3 76  ? 159.964 185.713 220.696 1.00 105.65 ? 76  ASP C C     1 
ATOM 2977 O O     . ASP C 3 76  ? 160.156 186.359 219.664 1.00 107.52 ? 76  ASP C O     1 
ATOM 2978 C CB    . ASP C 3 76  ? 158.832 186.956 222.560 1.00 109.83 ? 76  ASP C CB    1 
ATOM 2979 C CG    . ASP C 3 76  ? 158.539 188.294 221.907 1.00 112.61 ? 76  ASP C CG    1 
ATOM 2980 O OD1   . ASP C 3 76  ? 158.466 188.352 220.664 1.00 113.54 ? 76  ASP C OD1   1 
ATOM 2981 O OD2   . ASP C 3 76  ? 158.382 189.292 222.641 1.00 111.08 ? 76  ASP C OD2   1 
ATOM 2982 N N     . ILE C 3 77  ? 159.599 184.435 220.688 1.00 82.32  ? 77  ILE C N     1 
ATOM 2983 C CA    . ILE C 3 77  ? 159.459 183.659 219.464 1.00 83.42  ? 77  ILE C CA    1 
ATOM 2984 C C     . ILE C 3 77  ? 158.028 183.147 219.382 1.00 86.22  ? 77  ILE C C     1 
ATOM 2985 O O     . ILE C 3 77  ? 157.569 182.426 220.275 1.00 89.37  ? 77  ILE C O     1 
ATOM 2986 C CB    . ILE C 3 77  ? 160.470 182.501 219.410 1.00 79.89  ? 77  ILE C CB    1 
ATOM 2987 C CG1   . ILE C 3 77  ? 160.136 181.539 218.276 1.00 82.73  ? 77  ILE C CG1   1 
ATOM 2988 C CG2   . ILE C 3 77  ? 160.551 181.786 220.747 1.00 86.38  ? 77  ILE C CG2   1 
ATOM 2989 C CD1   . ILE C 3 77  ? 161.062 180.363 218.222 1.00 81.18  ? 77  ILE C CD1   1 
ATOM 2990 N N     . ARG C 3 78  ? 157.320 183.530 218.318 1.00 90.23  ? 78  ARG C N     1 
ATOM 2991 C CA    . ARG C 3 78  ? 155.923 183.132 218.174 1.00 88.20  ? 78  ARG C CA    1 
ATOM 2992 C C     . ARG C 3 78  ? 155.800 181.652 217.840 1.00 91.65  ? 78  ARG C C     1 
ATOM 2993 O O     . ARG C 3 78  ? 155.003 180.931 218.449 1.00 100.70 ? 78  ARG C O     1 
ATOM 2994 C CB    . ARG C 3 78  ? 155.249 183.973 217.094 1.00 94.16  ? 78  ARG C CB    1 
ATOM 2995 C CG    . ARG C 3 78  ? 154.042 183.312 216.459 1.00 98.90  ? 78  ARG C CG    1 
ATOM 2996 C CD    . ARG C 3 78  ? 152.831 183.406 217.368 1.00 103.96 ? 78  ARG C CD    1 
ATOM 2997 N NE    . ARG C 3 78  ? 152.523 184.786 217.723 1.00 105.04 ? 78  ARG C NE    1 
ATOM 2998 C CZ    . ARG C 3 78  ? 152.031 185.688 216.884 1.00 104.70 ? 78  ARG C CZ    1 
ATOM 2999 N NH1   . ARG C 3 78  ? 151.751 185.384 215.627 1.00 99.05  ? 78  ARG C NH1   1 
ATOM 3000 N NH2   . ARG C 3 78  ? 151.809 186.924 217.320 1.00 103.36 ? 78  ARG C NH2   1 
ATOM 3001 N N     . ARG C 3 79  ? 156.583 181.183 216.876 1.00 80.61  ? 79  ARG C N     1 
ATOM 3002 C CA    . ARG C 3 79  ? 156.442 179.829 216.371 1.00 82.27  ? 79  ARG C CA    1 
ATOM 3003 C C     . ARG C 3 79  ? 157.789 179.368 215.843 1.00 83.47  ? 79  ARG C C     1 
ATOM 3004 O O     . ARG C 3 79  ? 158.639 180.182 215.478 1.00 91.34  ? 79  ARG C O     1 
ATOM 3005 C CB    . ARG C 3 79  ? 155.376 179.762 215.271 1.00 81.07  ? 79  ARG C CB    1 
ATOM 3006 C CG    . ARG C 3 79  ? 155.016 178.364 214.806 1.00 78.74  ? 79  ARG C CG    1 
ATOM 3007 C CD    . ARG C 3 79  ? 154.250 178.412 213.494 1.00 83.76  ? 79  ARG C CD    1 
ATOM 3008 N NE    . ARG C 3 79  ? 155.107 178.763 212.368 1.00 87.83  ? 79  ARG C NE    1 
ATOM 3009 C CZ    . ARG C 3 79  ? 155.714 177.881 211.586 1.00 86.02  ? 79  ARG C CZ    1 
ATOM 3010 N NH1   . ARG C 3 79  ? 155.576 176.580 211.774 1.00 86.43  ? 79  ARG C NH1   1 
ATOM 3011 N NH2   . ARG C 3 79  ? 156.474 178.317 210.586 1.00 75.05  ? 79  ARG C NH2   1 
ATOM 3012 N N     . LEU C 3 80  ? 157.974 178.054 215.807 1.00 68.79  ? 80  LEU C N     1 
ATOM 3013 C CA    . LEU C 3 80  ? 159.218 177.472 215.339 1.00 62.57  ? 80  LEU C CA    1 
ATOM 3014 C C     . LEU C 3 80  ? 158.905 176.111 214.745 1.00 67.51  ? 80  LEU C C     1 
ATOM 3015 O O     . LEU C 3 80  ? 157.941 175.456 215.145 1.00 83.04  ? 80  LEU C O     1 
ATOM 3016 C CB    . LEU C 3 80  ? 160.231 177.358 216.486 1.00 68.84  ? 80  LEU C CB    1 
ATOM 3017 C CG    . LEU C 3 80  ? 161.525 176.554 216.352 1.00 75.74  ? 80  LEU C CG    1 
ATOM 3018 C CD1   . LEU C 3 80  ? 162.593 177.183 217.216 1.00 78.97  ? 80  LEU C CD1   1 
ATOM 3019 C CD2   . LEU C 3 80  ? 161.335 175.113 216.752 1.00 71.69  ? 80  LEU C CD2   1 
ATOM 3020 N N     . ARG C 3 81  ? 159.718 175.692 213.782 1.00 52.07  ? 81  ARG C N     1 
ATOM 3021 C CA    . ARG C 3 81  ? 159.620 174.332 213.269 1.00 57.48  ? 81  ARG C CA    1 
ATOM 3022 C C     . ARG C 3 81  ? 160.977 173.896 212.753 1.00 55.74  ? 81  ARG C C     1 
ATOM 3023 O O     . ARG C 3 81  ? 161.588 174.598 211.946 1.00 67.30  ? 81  ARG C O     1 
ATOM 3024 C CB    . ARG C 3 81  ? 158.582 174.211 212.155 1.00 54.78  ? 81  ARG C CB    1 
ATOM 3025 C CG    . ARG C 3 81  ? 158.829 172.975 211.304 1.00 59.60  ? 81  ARG C CG    1 
ATOM 3026 C CD    . ARG C 3 81  ? 157.709 172.650 210.341 1.00 63.62  ? 81  ARG C CD    1 
ATOM 3027 N NE    . ARG C 3 81  ? 157.949 171.353 209.720 1.00 56.59  ? 81  ARG C NE    1 
ATOM 3028 C CZ    . ARG C 3 81  ? 157.481 170.984 208.538 1.00 55.91  ? 81  ARG C CZ    1 
ATOM 3029 N NH1   . ARG C 3 81  ? 156.703 171.778 207.826 1.00 56.26  ? 81  ARG C NH1   1 
ATOM 3030 N NH2   . ARG C 3 81  ? 157.794 169.782 208.063 1.00 63.33  ? 81  ARG C NH2   1 
ATOM 3031 N N     . LEU C 3 82  ? 161.440 172.746 213.216 1.00 44.95  ? 82  LEU C N     1 
ATOM 3032 C CA    . LEU C 3 82  ? 162.545 172.069 212.568 1.00 48.07  ? 82  LEU C CA    1 
ATOM 3033 C C     . LEU C 3 82  ? 161.980 171.067 211.572 1.00 42.23  ? 82  LEU C C     1 
ATOM 3034 O O     . LEU C 3 82  ? 160.992 170.384 211.846 1.00 57.29  ? 82  LEU C O     1 
ATOM 3035 C CB    . LEU C 3 82  ? 163.438 171.373 213.594 1.00 52.95  ? 82  LEU C CB    1 
ATOM 3036 C CG    . LEU C 3 82  ? 164.665 170.638 213.060 1.00 50.09  ? 82  LEU C CG    1 
ATOM 3037 C CD1   . LEU C 3 82  ? 165.874 170.947 213.905 1.00 42.70  ? 82  LEU C CD1   1 
ATOM 3038 C CD2   . LEU C 3 82  ? 164.416 169.152 213.047 1.00 57.44  ? 82  LEU C CD2   1 
ATOM 3039 N N     . VAL C 3 83  ? 162.600 171.000 210.401 1.00 46.46  ? 83  VAL C N     1 
ATOM 3040 C CA    . VAL C 3 83  ? 162.096 170.196 209.296 1.00 40.53  ? 83  VAL C CA    1 
ATOM 3041 C C     . VAL C 3 83  ? 162.740 168.821 209.360 1.00 55.89  ? 83  VAL C C     1 
ATOM 3042 O O     . VAL C 3 83  ? 163.969 168.703 209.397 1.00 68.33  ? 83  VAL C O     1 
ATOM 3043 C CB    . VAL C 3 83  ? 162.371 170.869 207.945 1.00 41.04  ? 83  VAL C CB    1 
ATOM 3044 C CG1   . VAL C 3 83  ? 162.174 169.880 206.820 1.00 56.18  ? 83  VAL C CG1   1 
ATOM 3045 C CG2   . VAL C 3 83  ? 161.470 172.073 207.768 1.00 56.64  ? 83  VAL C CG2   1 
ATOM 3046 N N     . ARG C 3 84  ? 161.911 167.781 209.372 1.00 59.56  ? 84  ARG C N     1 
ATOM 3047 C CA    . ARG C 3 84  ? 162.368 166.402 209.356 1.00 61.25  ? 84  ARG C CA    1 
ATOM 3048 C C     . ARG C 3 84  ? 161.723 165.661 208.192 1.00 65.75  ? 84  ARG C C     1 
ATOM 3049 O O     . ARG C 3 84  ? 160.661 166.046 207.698 1.00 77.31  ? 84  ARG C O     1 
ATOM 3050 C CB    . ARG C 3 84  ? 162.041 165.689 210.671 1.00 64.38  ? 84  ARG C CB    1 
ATOM 3051 C CG    . ARG C 3 84  ? 161.875 166.618 211.854 1.00 67.97  ? 84  ARG C CG    1 
ATOM 3052 C CD    . ARG C 3 84  ? 161.783 165.839 213.148 1.00 65.86  ? 84  ARG C CD    1 
ATOM 3053 N NE    . ARG C 3 84  ? 163.056 165.233 213.511 1.00 65.12  ? 84  ARG C NE    1 
ATOM 3054 C CZ    . ARG C 3 84  ? 163.780 165.589 214.562 1.00 70.72  ? 84  ARG C CZ    1 
ATOM 3055 N NH1   . ARG C 3 84  ? 163.386 166.551 215.377 1.00 72.15  ? 84  ARG C NH1   1 
ATOM 3056 N NH2   . ARG C 3 84  ? 164.928 164.963 214.800 1.00 71.22  ? 84  ARG C NH2   1 
ATOM 3057 N N     . ASP C 3 85  ? 162.381 164.591 207.757 1.00 66.98  ? 85  ASP C N     1 
ATOM 3058 C CA    . ASP C 3 85  ? 161.879 163.809 206.637 1.00 67.81  ? 85  ASP C CA    1 
ATOM 3059 C C     . ASP C 3 85  ? 160.533 163.185 206.980 1.00 76.69  ? 85  ASP C C     1 
ATOM 3060 O O     . ASP C 3 85  ? 160.366 162.578 208.039 1.00 83.73  ? 85  ASP C O     1 
ATOM 3061 C CB    . ASP C 3 85  ? 162.877 162.721 206.262 1.00 70.38  ? 85  ASP C CB    1 
ATOM 3062 C CG    . ASP C 3 85  ? 162.495 162.000 204.995 1.00 77.45  ? 85  ASP C CG    1 
ATOM 3063 O OD1   . ASP C 3 85  ? 162.506 162.639 203.924 1.00 69.31  ? 85  ASP C OD1   1 
ATOM 3064 O OD2   . ASP C 3 85  ? 162.180 160.797 205.065 1.00 79.85  ? 85  ASP C OD2   1 
ATOM 3065 N N     . LEU C 3 86  ? 159.582 163.306 206.052 1.00 66.80  ? 86  LEU C N     1 
ATOM 3066 C CA    . LEU C 3 86  ? 158.196 162.950 206.341 1.00 59.45  ? 86  LEU C CA    1 
ATOM 3067 C C     . LEU C 3 86  ? 158.063 161.492 206.761 1.00 64.26  ? 86  LEU C C     1 
ATOM 3068 O O     . LEU C 3 86  ? 157.485 161.187 207.810 1.00 66.25  ? 86  LEU C O     1 
ATOM 3069 C CB    . LEU C 3 86  ? 157.329 163.228 205.116 1.00 59.28  ? 86  LEU C CB    1 
ATOM 3070 C CG    . LEU C 3 86  ? 155.832 163.001 205.286 1.00 66.97  ? 86  LEU C CG    1 
ATOM 3071 C CD1   . LEU C 3 86  ? 155.210 164.153 206.050 1.00 71.63  ? 86  LEU C CD1   1 
ATOM 3072 C CD2   . LEU C 3 86  ? 155.184 162.831 203.934 1.00 56.46  ? 86  LEU C CD2   1 
ATOM 3073 N N     . VAL C 3 87  ? 158.598 160.579 205.963 1.00 64.16  ? 87  VAL C N     1 
ATOM 3074 C CA    . VAL C 3 87  ? 158.444 159.158 206.248 1.00 64.55  ? 87  VAL C CA    1 
ATOM 3075 C C     . VAL C 3 87  ? 159.443 158.687 207.294 1.00 75.54  ? 87  VAL C C     1 
ATOM 3076 O O     . VAL C 3 87  ? 159.077 157.979 208.235 1.00 86.21  ? 87  VAL C O     1 
ATOM 3077 C CB    . VAL C 3 87  ? 158.579 158.349 204.946 1.00 72.48  ? 87  VAL C CB    1 
ATOM 3078 C CG1   . VAL C 3 87  ? 158.608 156.863 205.248 1.00 74.52  ? 87  VAL C CG1   1 
ATOM 3079 C CG2   . VAL C 3 87  ? 157.448 158.683 204.003 1.00 80.32  ? 87  VAL C CG2   1 
ATOM 3080 N N     . THR C 3 88  ? 160.708 159.077 207.156 1.00 72.99  ? 88  THR C N     1 
ATOM 3081 C CA    . THR C 3 88  ? 161.758 158.489 207.975 1.00 59.03  ? 88  THR C CA    1 
ATOM 3082 C C     . THR C 3 88  ? 161.860 159.144 209.345 1.00 68.69  ? 88  THR C C     1 
ATOM 3083 O O     . THR C 3 88  ? 162.016 158.449 210.352 1.00 80.90  ? 88  THR C O     1 
ATOM 3084 C CB    . THR C 3 88  ? 163.091 158.581 207.244 1.00 70.42  ? 88  THR C CB    1 
ATOM 3085 O OG1   . THR C 3 88  ? 163.133 157.597 206.206 1.00 79.34  ? 88  THR C OG1   1 
ATOM 3086 C CG2   . THR C 3 88  ? 164.223 158.342 208.195 1.00 77.24  ? 88  THR C CG2   1 
ATOM 3087 N N     . GLY C 3 89  ? 161.779 160.468 209.412 1.00 75.48  ? 89  GLY C N     1 
ATOM 3088 C CA    . GLY C 3 89  ? 161.976 161.188 210.648 1.00 74.45  ? 89  GLY C CA    1 
ATOM 3089 C C     . GLY C 3 89  ? 163.328 161.851 210.775 1.00 80.84  ? 89  GLY C C     1 
ATOM 3090 O O     . GLY C 3 89  ? 163.518 162.656 211.694 1.00 86.27  ? 89  GLY C O     1 
ATOM 3091 N N     . PHE C 3 90  ? 164.267 161.536 209.882 1.00 81.22  ? 90  PHE C N     1 
ATOM 3092 C CA    . PHE C 3 90  ? 165.584 162.155 209.903 1.00 69.97  ? 90  PHE C CA    1 
ATOM 3093 C C     . PHE C 3 90  ? 165.457 163.666 209.818 1.00 74.36  ? 90  PHE C C     1 
ATOM 3094 O O     . PHE C 3 90  ? 164.680 164.189 209.018 1.00 87.47  ? 90  PHE C O     1 
ATOM 3095 C CB    . PHE C 3 90  ? 166.422 161.642 208.734 1.00 66.60  ? 90  PHE C CB    1 
ATOM 3096 C CG    . PHE C 3 90  ? 167.371 160.548 209.103 1.00 74.86  ? 90  PHE C CG    1 
ATOM 3097 C CD1   . PHE C 3 90  ? 168.270 160.713 210.138 1.00 86.75  ? 90  PHE C CD1   1 
ATOM 3098 C CD2   . PHE C 3 90  ? 167.381 159.360 208.400 1.00 75.18  ? 90  PHE C CD2   1 
ATOM 3099 C CE1   . PHE C 3 90  ? 169.148 159.705 210.474 1.00 87.11  ? 90  PHE C CE1   1 
ATOM 3100 C CE2   . PHE C 3 90  ? 168.252 158.348 208.731 1.00 75.60  ? 90  PHE C CE2   1 
ATOM 3101 C CZ    . PHE C 3 90  ? 169.139 158.520 209.767 1.00 81.76  ? 90  PHE C CZ    1 
ATOM 3102 N N     . SER C 3 91  ? 166.210 164.365 210.659 1.00 65.57  ? 91  SER C N     1 
ATOM 3103 C CA    . SER C 3 91  ? 166.242 165.816 210.576 1.00 64.78  ? 91  SER C CA    1 
ATOM 3104 C C     . SER C 3 91  ? 166.877 166.241 209.262 1.00 74.78  ? 91  SER C C     1 
ATOM 3105 O O     . SER C 3 91  ? 167.884 165.675 208.830 1.00 85.36  ? 91  SER C O     1 
ATOM 3106 C CB    . SER C 3 91  ? 167.017 166.404 211.749 1.00 75.96  ? 91  SER C CB    1 
ATOM 3107 O OG    . SER C 3 91  ? 167.025 167.818 211.684 1.00 75.91  ? 91  SER C OG    1 
ATOM 3108 N N     . LYS C 3 92  ? 166.278 167.233 208.616 1.00 77.44  ? 92  LYS C N     1 
ATOM 3109 C CA    . LYS C 3 92  ? 166.788 167.717 207.343 1.00 67.55  ? 92  LYS C CA    1 
ATOM 3110 C C     . LYS C 3 92  ? 167.891 168.749 207.506 1.00 72.17  ? 92  LYS C C     1 
ATOM 3111 O O     . LYS C 3 92  ? 168.455 169.197 206.503 1.00 84.76  ? 92  LYS C O     1 
ATOM 3112 C CB    . LYS C 3 92  ? 165.648 168.291 206.498 1.00 56.59  ? 92  LYS C CB    1 
ATOM 3113 C CG    . LYS C 3 92  ? 164.929 167.241 205.672 1.00 62.15  ? 92  LYS C CG    1 
ATOM 3114 C CD    . LYS C 3 92  ? 165.931 166.413 204.889 1.00 66.09  ? 92  LYS C CD    1 
ATOM 3115 C CE    . LYS C 3 92  ? 165.255 165.342 204.064 1.00 73.48  ? 92  LYS C CE    1 
ATOM 3116 N NZ    . LYS C 3 92  ? 166.216 164.287 203.651 1.00 72.09  ? 92  LYS C NZ    1 
ATOM 3117 N N     . GLY C 3 93  ? 168.223 169.122 208.737 1.00 76.80  ? 93  GLY C N     1 
ATOM 3118 C CA    . GLY C 3 93  ? 169.323 170.034 208.962 1.00 75.30  ? 93  GLY C CA    1 
ATOM 3119 C C     . GLY C 3 93  ? 168.988 171.496 208.792 1.00 76.77  ? 93  GLY C C     1 
ATOM 3120 O O     . GLY C 3 93  ? 169.899 172.321 208.710 1.00 88.50  ? 93  GLY C O     1 
ATOM 3121 N N     . TYR C 3 94  ? 167.708 171.847 208.739 1.00 39.52  ? 94  TYR C N     1 
ATOM 3122 C CA    . TYR C 3 94  ? 167.346 173.253 208.671 1.00 41.36  ? 94  TYR C CA    1 
ATOM 3123 C C     . TYR C 3 94  ? 165.978 173.450 209.295 1.00 47.47  ? 94  TYR C C     1 
ATOM 3124 O O     . TYR C 3 94  ? 165.169 172.523 209.331 1.00 75.86  ? 94  TYR C O     1 
ATOM 3125 C CB    . TYR C 3 94  ? 167.382 173.774 207.230 1.00 60.78  ? 94  TYR C CB    1 
ATOM 3126 C CG    . TYR C 3 94  ? 166.442 173.104 206.258 1.00 56.88  ? 94  TYR C CG    1 
ATOM 3127 C CD1   . TYR C 3 94  ? 166.804 171.934 205.613 1.00 64.24  ? 94  TYR C CD1   1 
ATOM 3128 C CD2   . TYR C 3 94  ? 165.220 173.671 205.940 1.00 61.50  ? 94  TYR C CD2   1 
ATOM 3129 C CE1   . TYR C 3 94  ? 165.965 171.328 204.712 1.00 60.34  ? 94  TYR C CE1   1 
ATOM 3130 C CE2   . TYR C 3 94  ? 164.372 173.070 205.038 1.00 57.36  ? 94  TYR C CE2   1 
ATOM 3131 C CZ    . TYR C 3 94  ? 164.753 171.899 204.428 1.00 58.12  ? 94  TYR C CZ    1 
ATOM 3132 O OH    . TYR C 3 94  ? 163.918 171.291 203.527 1.00 66.90  ? 94  TYR C OH    1 
ATOM 3133 N N     . ALA C 3 95  ? 165.740 174.652 209.799 1.00 44.64  ? 95  ALA C N     1 
ATOM 3134 C CA    . ALA C 3 95  ? 164.546 174.990 210.555 1.00 52.55  ? 95  ALA C CA    1 
ATOM 3135 C C     . ALA C 3 95  ? 163.979 176.307 210.055 1.00 51.34  ? 95  ALA C C     1 
ATOM 3136 O O     . ALA C 3 95  ? 164.537 176.953 209.172 1.00 65.05  ? 95  ALA C O     1 
ATOM 3137 C CB    . ALA C 3 95  ? 164.854 175.075 212.050 1.00 45.90  ? 95  ALA C CB    1 
ATOM 3138 N N     . PHE C 3 96  ? 162.846 176.700 210.627 1.00 48.56  ? 96  PHE C N     1 
ATOM 3139 C CA    . PHE C 3 96  ? 162.211 177.968 210.298 1.00 50.78  ? 96  PHE C CA    1 
ATOM 3140 C C     . PHE C 3 96  ? 161.713 178.601 211.584 1.00 57.90  ? 96  PHE C C     1 
ATOM 3141 O O     . PHE C 3 96  ? 160.845 178.039 212.255 1.00 66.65  ? 96  PHE C O     1 
ATOM 3142 C CB    . PHE C 3 96  ? 161.063 177.774 209.307 1.00 47.55  ? 96  PHE C CB    1 
ATOM 3143 C CG    . PHE C 3 96  ? 161.507 177.336 207.942 1.00 58.96  ? 96  PHE C CG    1 
ATOM 3144 C CD1   . PHE C 3 96  ? 161.781 176.004 207.680 1.00 53.01  ? 96  PHE C CD1   1 
ATOM 3145 C CD2   . PHE C 3 96  ? 161.650 178.256 206.922 1.00 60.14  ? 96  PHE C CD2   1 
ATOM 3146 C CE1   . PHE C 3 96  ? 162.189 175.601 206.428 1.00 58.03  ? 96  PHE C CE1   1 
ATOM 3147 C CE2   . PHE C 3 96  ? 162.058 177.859 205.671 1.00 53.95  ? 96  PHE C CE2   1 
ATOM 3148 C CZ    . PHE C 3 96  ? 162.327 176.529 205.423 1.00 58.02  ? 96  PHE C CZ    1 
ATOM 3149 N N     . ILE C 3 97  ? 162.251 179.768 211.916 1.00 63.98  ? 97  ILE C N     1 
ATOM 3150 C CA    . ILE C 3 97  ? 161.975 180.444 213.177 1.00 62.06  ? 97  ILE C CA    1 
ATOM 3151 C C     . ILE C 3 97  ? 161.062 181.621 212.875 1.00 61.63  ? 97  ILE C C     1 
ATOM 3152 O O     . ILE C 3 97  ? 161.439 182.533 212.132 1.00 76.86  ? 97  ILE C O     1 
ATOM 3153 C CB    . ILE C 3 97  ? 163.264 180.913 213.864 1.00 69.53  ? 97  ILE C CB    1 
ATOM 3154 C CG1   . ILE C 3 97  ? 164.394 179.910 213.636 1.00 73.32  ? 97  ILE C CG1   1 
ATOM 3155 C CG2   . ILE C 3 97  ? 163.036 181.112 215.341 1.00 69.71  ? 97  ILE C CG2   1 
ATOM 3156 C CD1   . ILE C 3 97  ? 164.232 178.625 214.389 1.00 64.08  ? 97  ILE C CD1   1 
ATOM 3157 N N     . GLU C 3 98  ? 159.867 181.612 213.450 1.00 63.72  ? 98  GLU C N     1 
ATOM 3158 C CA    . GLU C 3 98  ? 158.922 182.707 213.296 1.00 72.44  ? 98  GLU C CA    1 
ATOM 3159 C C     . GLU C 3 98  ? 158.979 183.578 214.541 1.00 78.11  ? 98  GLU C C     1 
ATOM 3160 O O     . GLU C 3 98  ? 158.797 183.081 215.656 1.00 90.14  ? 98  GLU C O     1 
ATOM 3161 C CB    . GLU C 3 98  ? 157.506 182.184 213.070 1.00 87.14  ? 98  GLU C CB    1 
ATOM 3162 C CG    . GLU C 3 98  ? 156.504 183.262 212.694 1.00 94.53  ? 98  GLU C CG    1 
ATOM 3163 C CD    . GLU C 3 98  ? 155.128 182.701 212.398 1.00 95.92  ? 98  GLU C CD    1 
ATOM 3164 O OE1   . GLU C 3 98  ? 155.045 181.574 211.867 1.00 94.33  ? 98  GLU C OE1   1 
ATOM 3165 O OE2   . GLU C 3 98  ? 154.129 183.386 212.700 1.00 96.40  ? 98  GLU C OE2   1 
ATOM 3166 N N     . TYR C 3 99  ? 159.221 184.866 214.350 1.00 80.10  ? 99  TYR C N     1 
ATOM 3167 C CA    . TYR C 3 99  ? 159.423 185.801 215.444 1.00 79.73  ? 99  TYR C CA    1 
ATOM 3168 C C     . TYR C 3 99  ? 158.232 186.744 215.568 1.00 85.40  ? 99  TYR C C     1 
ATOM 3169 O O     . TYR C 3 99  ? 157.293 186.714 214.771 1.00 88.58  ? 99  TYR C O     1 
ATOM 3170 C CB    . TYR C 3 99  ? 160.715 186.593 215.237 1.00 88.11  ? 99  TYR C CB    1 
ATOM 3171 C CG    . TYR C 3 99  ? 161.960 185.885 215.708 1.00 89.42  ? 99  TYR C CG    1 
ATOM 3172 C CD1   . TYR C 3 99  ? 162.294 185.853 217.049 1.00 91.74  ? 99  TYR C CD1   1 
ATOM 3173 C CD2   . TYR C 3 99  ? 162.804 185.256 214.809 1.00 89.37  ? 99  TYR C CD2   1 
ATOM 3174 C CE1   . TYR C 3 99  ? 163.428 185.213 217.483 1.00 92.92  ? 99  TYR C CE1   1 
ATOM 3175 C CE2   . TYR C 3 99  ? 163.939 184.613 215.234 1.00 85.29  ? 99  TYR C CE2   1 
ATOM 3176 C CZ    . TYR C 3 99  ? 164.247 184.594 216.571 1.00 92.04  ? 99  TYR C CZ    1 
ATOM 3177 O OH    . TYR C 3 99  ? 165.381 183.954 217.003 1.00 94.93  ? 99  TYR C OH    1 
ATOM 3178 N N     . LYS C 3 100 ? 158.286 187.589 216.591 1.00 97.69  ? 100 LYS C N     1 
ATOM 3179 C CA    . LYS C 3 100 ? 157.329 188.667 216.791 1.00 99.53  ? 100 LYS C CA    1 
ATOM 3180 C C     . LYS C 3 100 ? 158.088 189.982 216.776 1.00 105.27 ? 100 LYS C C     1 
ATOM 3181 O O     . LYS C 3 100 ? 159.159 190.084 217.385 1.00 104.85 ? 100 LYS C O     1 
ATOM 3182 C CB    . LYS C 3 100 ? 156.576 188.506 218.110 1.00 99.19  ? 100 LYS C CB    1 
ATOM 3183 C CG    . LYS C 3 100 ? 155.776 187.229 218.214 1.00 101.09 ? 100 LYS C CG    1 
ATOM 3184 C CD    . LYS C 3 100 ? 155.152 187.083 219.590 1.00 104.19 ? 100 LYS C CD    1 
ATOM 3185 C CE    . LYS C 3 100 ? 154.082 188.133 219.829 1.00 106.54 ? 100 LYS C CE    1 
ATOM 3186 N NZ    . LYS C 3 100 ? 153.361 187.901 221.111 1.00 105.01 ? 100 LYS C NZ    1 
ATOM 3187 N N     . GLU C 3 101 ? 157.542 190.972 216.062 1.00 126.58 ? 101 GLU C N     1 
ATOM 3188 C CA    . GLU C 3 101 ? 158.160 192.284 215.879 1.00 128.91 ? 101 GLU C CA    1 
ATOM 3189 C C     . GLU C 3 101 ? 159.394 192.150 214.994 1.00 129.02 ? 101 GLU C C     1 
ATOM 3190 O O     . GLU C 3 101 ? 160.220 191.256 215.203 1.00 124.46 ? 101 GLU C O     1 
ATOM 3191 C CB    . GLU C 3 101 ? 158.509 192.914 217.233 1.00 128.97 ? 101 GLU C CB    1 
ATOM 3192 C CG    . GLU C 3 101 ? 157.560 194.003 217.701 1.00 129.16 ? 101 GLU C CG    1 
ATOM 3193 C CD    . GLU C 3 101 ? 158.022 195.393 217.318 1.00 130.41 ? 101 GLU C CD    1 
ATOM 3194 O OE1   . GLU C 3 101 ? 158.835 195.516 216.381 1.00 125.80 ? 101 GLU C OE1   1 
ATOM 3195 O OE2   . GLU C 3 101 ? 157.578 196.365 217.963 1.00 132.93 ? 101 GLU C OE2   1 
ATOM 3196 N N     . GLU C 3 102 ? 159.544 193.033 214.005 1.00 136.69 ? 102 GLU C N     1 
ATOM 3197 C CA    . GLU C 3 102 ? 160.658 192.882 213.077 1.00 136.10 ? 102 GLU C CA    1 
ATOM 3198 C C     . GLU C 3 102 ? 161.995 193.225 213.716 1.00 130.84 ? 102 GLU C C     1 
ATOM 3199 O O     . GLU C 3 102 ? 163.039 192.936 213.124 1.00 129.94 ? 102 GLU C O     1 
ATOM 3200 C CB    . GLU C 3 102 ? 160.460 193.743 211.822 1.00 134.82 ? 102 GLU C CB    1 
ATOM 3201 C CG    . GLU C 3 102 ? 160.557 195.275 211.976 1.00 135.80 ? 102 GLU C CG    1 
ATOM 3202 C CD    . GLU C 3 102 ? 159.777 195.869 213.142 1.00 137.72 ? 102 GLU C CD    1 
ATOM 3203 O OE1   . GLU C 3 102 ? 159.942 197.082 213.395 1.00 137.22 ? 102 GLU C OE1   1 
ATOM 3204 O OE2   . GLU C 3 102 ? 158.942 195.172 213.750 1.00 139.01 ? 102 GLU C OE2   1 
ATOM 3205 N N     . ARG C 3 103 ? 161.990 193.827 214.906 1.00 105.52 ? 103 ARG C N     1 
ATOM 3206 C CA    . ARG C 3 103 ? 163.246 194.118 215.588 1.00 108.43 ? 103 ARG C CA    1 
ATOM 3207 C C     . ARG C 3 103 ? 163.989 192.836 215.941 1.00 107.92 ? 103 ARG C C     1 
ATOM 3208 O O     . ARG C 3 103 ? 165.222 192.783 215.871 1.00 105.17 ? 103 ARG C O     1 
ATOM 3209 C CB    . ARG C 3 103 ? 162.976 194.950 216.842 1.00 109.43 ? 103 ARG C CB    1 
ATOM 3210 C CG    . ARG C 3 103 ? 164.073 194.882 217.888 1.00 106.84 ? 103 ARG C CG    1 
ATOM 3211 C CD    . ARG C 3 103 ? 163.572 195.348 219.242 1.00 107.58 ? 103 ARG C CD    1 
ATOM 3212 N NE    . ARG C 3 103 ? 164.625 195.978 220.027 1.00 110.75 ? 103 ARG C NE    1 
ATOM 3213 C CZ    . ARG C 3 103 ? 165.483 195.318 220.792 1.00 109.73 ? 103 ARG C CZ    1 
ATOM 3214 N NH1   . ARG C 3 103 ? 165.440 194.001 220.901 1.00 108.47 ? 103 ARG C NH1   1 
ATOM 3215 N NH2   . ARG C 3 103 ? 166.405 195.997 221.468 1.00 105.46 ? 103 ARG C NH2   1 
ATOM 3216 N N     . ALA C 3 104 ? 163.256 191.792 216.325 1.00 114.27 ? 104 ALA C N     1 
ATOM 3217 C CA    . ALA C 3 104 ? 163.903 190.561 216.766 1.00 116.85 ? 104 ALA C CA    1 
ATOM 3218 C C     . ALA C 3 104 ? 164.585 189.837 215.612 1.00 114.52 ? 104 ALA C C     1 
ATOM 3219 O O     . ALA C 3 104 ? 165.700 189.325 215.764 1.00 113.79 ? 104 ALA C O     1 
ATOM 3220 C CB    . ALA C 3 104 ? 162.880 189.648 217.440 1.00 116.08 ? 104 ALA C CB    1 
ATOM 3221 N N     . VAL C 3 105 ? 163.929 189.776 214.452 1.00 102.65 ? 105 VAL C N     1 
ATOM 3222 C CA    . VAL C 3 105 ? 164.455 188.964 213.360 1.00 99.30  ? 105 VAL C CA    1 
ATOM 3223 C C     . VAL C 3 105 ? 165.714 189.584 212.760 1.00 102.89 ? 105 VAL C C     1 
ATOM 3224 O O     . VAL C 3 105 ? 166.651 188.862 212.395 1.00 105.39 ? 105 VAL C O     1 
ATOM 3225 C CB    . VAL C 3 105 ? 163.362 188.723 212.301 1.00 96.71  ? 105 VAL C CB    1 
ATOM 3226 C CG1   . VAL C 3 105 ? 162.896 190.029 211.686 1.00 102.51 ? 105 VAL C CG1   1 
ATOM 3227 C CG2   . VAL C 3 105 ? 163.856 187.759 211.236 1.00 95.31  ? 105 VAL C CG2   1 
ATOM 3228 N N     . ILE C 3 106 ? 165.769 190.914 212.643 1.00 108.03 ? 106 ILE C N     1 
ATOM 3229 C CA    . ILE C 3 106 ? 166.963 191.547 212.090 1.00 108.38 ? 106 ILE C CA    1 
ATOM 3230 C C     . ILE C 3 106 ? 168.148 191.322 213.021 1.00 105.39 ? 106 ILE C C     1 
ATOM 3231 O O     . ILE C 3 106 ? 169.268 191.051 212.572 1.00 105.94 ? 106 ILE C O     1 
ATOM 3232 C CB    . ILE C 3 106 ? 166.711 193.045 211.831 1.00 109.17 ? 106 ILE C CB    1 
ATOM 3233 C CG1   . ILE C 3 106 ? 168.012 193.784 211.512 1.00 110.46 ? 106 ILE C CG1   1 
ATOM 3234 C CG2   . ILE C 3 106 ? 166.055 193.696 213.023 1.00 107.98 ? 106 ILE C CG2   1 
ATOM 3235 C CD1   . ILE C 3 106 ? 168.790 193.201 210.346 1.00 107.67 ? 106 ILE C CD1   1 
ATOM 3236 N N     . LYS C 3 107 ? 167.916 191.406 214.333 1.00 93.64  ? 107 LYS C N     1 
ATOM 3237 C CA    . LYS C 3 107 ? 168.951 191.038 215.290 1.00 97.80  ? 107 LYS C CA    1 
ATOM 3238 C C     . LYS C 3 107 ? 169.366 189.588 215.092 1.00 99.70  ? 107 LYS C C     1 
ATOM 3239 O O     . LYS C 3 107 ? 170.551 189.251 215.173 1.00 104.64 ? 107 LYS C O     1 
ATOM 3240 C CB    . LYS C 3 107 ? 168.456 191.273 216.716 1.00 99.81  ? 107 LYS C CB    1 
ATOM 3241 C CG    . LYS C 3 107 ? 169.458 190.885 217.791 1.00 99.54  ? 107 LYS C CG    1 
ATOM 3242 C CD    . LYS C 3 107 ? 168.840 190.944 219.179 1.00 100.76 ? 107 LYS C CD    1 
ATOM 3243 C CE    . LYS C 3 107 ? 168.520 192.374 219.581 1.00 100.74 ? 107 LYS C CE    1 
ATOM 3244 N NZ    . LYS C 3 107 ? 168.004 192.456 220.974 1.00 96.92  ? 107 LYS C NZ    1 
ATOM 3245 N N     . ALA C 3 108 ? 168.398 188.715 214.823 1.00 83.44  ? 108 ALA C N     1 
ATOM 3246 C CA    . ALA C 3 108 ? 168.728 187.334 214.501 1.00 81.09  ? 108 ALA C CA    1 
ATOM 3247 C C     . ALA C 3 108 ? 169.517 187.248 213.203 1.00 81.12  ? 108 ALA C C     1 
ATOM 3248 O O     . ALA C 3 108 ? 170.382 186.379 213.049 1.00 85.27  ? 108 ALA C O     1 
ATOM 3249 C CB    . ALA C 3 108 ? 167.452 186.503 214.408 1.00 87.84  ? 108 ALA C CB    1 
ATOM 3250 N N     . TYR C 3 109 ? 169.228 188.140 212.255 1.00 85.62  ? 109 TYR C N     1 
ATOM 3251 C CA    . TYR C 3 109 ? 169.927 188.124 210.975 1.00 88.48  ? 109 TYR C CA    1 
ATOM 3252 C C     . TYR C 3 109 ? 171.415 188.406 211.154 1.00 95.94  ? 109 TYR C C     1 
ATOM 3253 O O     . TYR C 3 109 ? 172.266 187.634 210.697 1.00 94.51  ? 109 TYR C O     1 
ATOM 3254 C CB    . TYR C 3 109 ? 169.295 189.159 210.041 1.00 88.52  ? 109 TYR C CB    1 
ATOM 3255 C CG    . TYR C 3 109 ? 169.644 189.044 208.570 1.00 86.36  ? 109 TYR C CG    1 
ATOM 3256 C CD1   . TYR C 3 109 ? 170.718 188.283 208.132 1.00 83.83  ? 109 TYR C CD1   1 
ATOM 3257 C CD2   . TYR C 3 109 ? 168.918 189.745 207.621 1.00 90.03  ? 109 TYR C CD2   1 
ATOM 3258 C CE1   . TYR C 3 109 ? 171.034 188.201 206.797 1.00 87.07  ? 109 TYR C CE1   1 
ATOM 3259 C CE2   . TYR C 3 109 ? 169.232 189.670 206.284 1.00 94.43  ? 109 TYR C CE2   1 
ATOM 3260 C CZ    . TYR C 3 109 ? 170.290 188.896 205.878 1.00 94.55  ? 109 TYR C CZ    1 
ATOM 3261 O OH    . TYR C 3 109 ? 170.605 188.818 204.543 1.00 96.78  ? 109 TYR C OH    1 
ATOM 3262 N N     . ARG C 3 110 ? 171.745 189.504 211.834 1.00 101.63 ? 110 ARG C N     1 
ATOM 3263 C CA    . ARG C 3 110 ? 173.096 190.048 211.753 1.00 95.85  ? 110 ARG C CA    1 
ATOM 3264 C C     . ARG C 3 110 ? 174.095 189.289 212.623 1.00 94.27  ? 110 ARG C C     1 
ATOM 3265 O O     . ARG C 3 110 ? 175.268 189.175 212.254 1.00 98.89  ? 110 ARG C O     1 
ATOM 3266 C CB    . ARG C 3 110 ? 173.069 191.539 212.104 1.00 94.66  ? 110 ARG C CB    1 
ATOM 3267 C CG    . ARG C 3 110 ? 172.986 191.853 213.580 1.00 99.49  ? 110 ARG C CG    1 
ATOM 3268 C CD    . ARG C 3 110 ? 173.326 193.306 213.863 1.00 101.99 ? 110 ARG C CD    1 
ATOM 3269 N NE    . ARG C 3 110 ? 172.989 193.685 215.230 1.00 108.43 ? 110 ARG C NE    1 
ATOM 3270 C CZ    . ARG C 3 110 ? 172.232 194.724 215.555 1.00 106.97 ? 110 ARG C CZ    1 
ATOM 3271 N NH1   . ARG C 3 110 ? 171.717 195.519 214.633 1.00 103.78 ? 110 ARG C NH1   1 
ATOM 3272 N NH2   . ARG C 3 110 ? 171.985 194.970 216.839 1.00 103.38 ? 110 ARG C NH2   1 
ATOM 3273 N N     . ASP C 3 111 ? 173.668 188.752 213.766 1.00 83.01  ? 111 ASP C N     1 
ATOM 3274 C CA    . ASP C 3 111 ? 174.613 188.128 214.687 1.00 93.44  ? 111 ASP C CA    1 
ATOM 3275 C C     . ASP C 3 111 ? 174.626 186.609 214.619 1.00 89.15  ? 111 ASP C C     1 
ATOM 3276 O O     . ASP C 3 111 ? 175.686 186.000 214.786 1.00 93.05  ? 111 ASP C O     1 
ATOM 3277 C CB    . ASP C 3 111 ? 174.327 188.550 216.132 1.00 99.39  ? 111 ASP C CB    1 
ATOM 3278 C CG    . ASP C 3 111 ? 173.858 189.981 216.245 1.00 99.63  ? 111 ASP C CG    1 
ATOM 3279 O OD1   . ASP C 3 111 ? 174.694 190.893 216.082 1.00 99.14  ? 111 ASP C OD1   1 
ATOM 3280 O OD2   . ASP C 3 111 ? 172.662 190.199 216.520 1.00 97.90  ? 111 ASP C OD2   1 
ATOM 3281 N N     . ALA C 3 112 ? 173.478 185.975 214.387 1.00 72.50  ? 112 ALA C N     1 
ATOM 3282 C CA    . ALA C 3 112 ? 173.406 184.526 214.518 1.00 76.27  ? 112 ALA C CA    1 
ATOM 3283 C C     . ALA C 3 112 ? 174.118 183.785 213.399 1.00 74.95  ? 112 ALA C C     1 
ATOM 3284 O O     . ALA C 3 112 ? 174.295 182.569 213.507 1.00 76.70  ? 112 ALA C O     1 
ATOM 3285 C CB    . ALA C 3 112 ? 171.949 184.076 214.582 1.00 83.66  ? 112 ALA C CB    1 
ATOM 3286 N N     . ASP C 3 113 ? 174.521 184.467 212.335 1.00 77.81  ? 113 ASP C N     1 
ATOM 3287 C CA    . ASP C 3 113 ? 175.216 183.799 211.239 1.00 84.82  ? 113 ASP C CA    1 
ATOM 3288 C C     . ASP C 3 113 ? 176.629 183.472 211.698 1.00 92.05  ? 113 ASP C C     1 
ATOM 3289 O O     . ASP C 3 113 ? 177.398 184.358 212.071 1.00 97.34  ? 113 ASP C O     1 
ATOM 3290 C CB    . ASP C 3 113 ? 175.220 184.673 209.992 1.00 86.67  ? 113 ASP C CB    1 
ATOM 3291 C CG    . ASP C 3 113 ? 175.703 183.928 208.766 1.00 91.75  ? 113 ASP C CG    1 
ATOM 3292 O OD1   . ASP C 3 113 ? 175.982 182.717 208.876 1.00 96.31  ? 113 ASP C OD1   1 
ATOM 3293 O OD2   . ASP C 3 113 ? 175.797 184.549 207.689 1.00 88.50  ? 113 ASP C OD2   1 
ATOM 3294 N N     . GLY C 3 114 ? 176.974 182.189 211.677 1.00 94.71  ? 114 GLY C N     1 
ATOM 3295 C CA    . GLY C 3 114 ? 178.239 181.703 212.190 1.00 89.78  ? 114 GLY C CA    1 
ATOM 3296 C C     . GLY C 3 114 ? 178.185 181.254 213.633 1.00 87.68  ? 114 GLY C C     1 
ATOM 3297 O O     . GLY C 3 114 ? 179.156 180.661 214.123 1.00 89.71  ? 114 GLY C O     1 
ATOM 3298 N N     . LEU C 3 115 ? 177.086 181.521 214.331 1.00 83.75  ? 115 LEU C N     1 
ATOM 3299 C CA    . LEU C 3 115 ? 176.926 181.097 215.715 1.00 77.51  ? 115 LEU C CA    1 
ATOM 3300 C C     . LEU C 3 115 ? 177.053 179.588 215.818 1.00 78.34  ? 115 LEU C C     1 
ATOM 3301 O O     . LEU C 3 115 ? 176.283 178.848 215.203 1.00 92.28  ? 115 LEU C O     1 
ATOM 3302 C CB    . LEU C 3 115 ? 175.564 181.557 216.236 1.00 81.20  ? 115 LEU C CB    1 
ATOM 3303 C CG    . LEU C 3 115 ? 175.318 181.567 217.741 1.00 81.42  ? 115 LEU C CG    1 
ATOM 3304 C CD1   . LEU C 3 115 ? 176.034 182.738 218.386 1.00 83.50  ? 115 LEU C CD1   1 
ATOM 3305 C CD2   . LEU C 3 115 ? 173.831 181.631 218.023 1.00 83.64  ? 115 LEU C CD2   1 
ATOM 3306 N N     . VAL C 3 116 ? 178.037 179.127 216.587 1.00 75.62  ? 116 VAL C N     1 
ATOM 3307 C CA    . VAL C 3 116 ? 178.287 177.696 216.681 1.00 81.06  ? 116 VAL C CA    1 
ATOM 3308 C C     . VAL C 3 116 ? 177.204 177.048 217.529 1.00 83.26  ? 116 VAL C C     1 
ATOM 3309 O O     . VAL C 3 116 ? 176.957 177.455 218.671 1.00 87.10  ? 116 VAL C O     1 
ATOM 3310 C CB    . VAL C 3 116 ? 179.683 177.424 217.255 1.00 85.19  ? 116 VAL C CB    1 
ATOM 3311 C CG1   . VAL C 3 116 ? 179.808 175.965 217.664 1.00 86.25  ? 116 VAL C CG1   1 
ATOM 3312 C CG2   . VAL C 3 116 ? 180.750 177.786 216.238 1.00 82.32  ? 116 VAL C CG2   1 
ATOM 3313 N N     . ILE C 3 117 ? 176.544 176.039 216.968 1.00 82.06  ? 117 ILE C N     1 
ATOM 3314 C CA    . ILE C 3 117 ? 175.536 175.263 217.676 1.00 82.55  ? 117 ILE C CA    1 
ATOM 3315 C C     . ILE C 3 117 ? 175.857 173.794 217.465 1.00 83.33  ? 117 ILE C C     1 
ATOM 3316 O O     . ILE C 3 117 ? 175.850 173.314 216.326 1.00 87.18  ? 117 ILE C O     1 
ATOM 3317 C CB    . ILE C 3 117 ? 174.114 175.582 217.190 1.00 77.54  ? 117 ILE C CB    1 
ATOM 3318 C CG1   . ILE C 3 117 ? 173.614 176.870 217.835 1.00 73.34  ? 117 ILE C CG1   1 
ATOM 3319 C CG2   . ILE C 3 117 ? 173.169 174.449 217.529 1.00 78.82  ? 117 ILE C CG2   1 
ATOM 3320 C CD1   . ILE C 3 117 ? 172.294 177.326 217.290 1.00 73.61  ? 117 ILE C CD1   1 
ATOM 3321 N N     . ASP C 3 118 ? 176.137 173.085 218.556 1.00 95.01  ? 118 ASP C N     1 
ATOM 3322 C CA    . ASP C 3 118 ? 176.460 171.662 218.513 1.00 96.67  ? 118 ASP C CA    1 
ATOM 3323 C C     . ASP C 3 118 ? 177.561 171.380 217.494 1.00 98.27  ? 118 ASP C C     1 
ATOM 3324 O O     . ASP C 3 118 ? 177.426 170.531 216.611 1.00 102.35 ? 118 ASP C O     1 
ATOM 3325 C CB    . ASP C 3 118 ? 175.213 170.830 218.220 1.00 100.21 ? 118 ASP C CB    1 
ATOM 3326 C CG    . ASP C 3 118 ? 175.360 169.386 218.656 1.00 104.84 ? 118 ASP C CG    1 
ATOM 3327 O OD1   . ASP C 3 118 ? 176.499 168.963 218.942 1.00 105.06 ? 118 ASP C OD1   1 
ATOM 3328 O OD2   . ASP C 3 118 ? 174.336 168.674 218.719 1.00 104.44 ? 118 ASP C OD2   1 
ATOM 3329 N N     . GLN C 3 119 ? 178.665 172.116 217.621 1.00 98.49  ? 119 GLN C N     1 
ATOM 3330 C CA    . GLN C 3 119 ? 179.857 172.012 216.784 1.00 100.17 ? 119 GLN C CA    1 
ATOM 3331 C C     . GLN C 3 119 ? 179.585 172.301 215.314 1.00 101.59 ? 119 GLN C C     1 
ATOM 3332 O O     . GLN C 3 119 ? 180.294 171.766 214.454 1.00 105.92 ? 119 GLN C O     1 
ATOM 3333 C CB    . GLN C 3 119 ? 180.536 170.638 216.892 1.00 102.38 ? 119 GLN C CB    1 
ATOM 3334 C CG    . GLN C 3 119 ? 180.510 170.029 218.283 1.00 104.44 ? 119 GLN C CG    1 
ATOM 3335 C CD    . GLN C 3 119 ? 180.822 168.549 218.271 1.00 105.87 ? 119 GLN C CD    1 
ATOM 3336 O OE1   . GLN C 3 119 ? 180.372 167.816 217.392 1.00 104.36 ? 119 GLN C OE1   1 
ATOM 3337 N NE2   . GLN C 3 119 ? 181.597 168.099 219.251 1.00 105.01 ? 119 GLN C NE2   1 
ATOM 3338 N N     . HIS C 3 120 ? 178.583 173.110 214.991 1.00 87.74  ? 120 HIS C N     1 
ATOM 3339 C CA    . HIS C 3 120 ? 178.299 173.503 213.619 1.00 87.67  ? 120 HIS C CA    1 
ATOM 3340 C C     . HIS C 3 120 ? 178.114 175.009 213.539 1.00 88.55  ? 120 HIS C C     1 
ATOM 3341 O O     . HIS C 3 120 ? 177.460 175.609 214.396 1.00 93.50  ? 120 HIS C O     1 
ATOM 3342 C CB    . HIS C 3 120 ? 177.045 172.806 213.092 1.00 88.25  ? 120 HIS C CB    1 
ATOM 3343 C CG    . HIS C 3 120 ? 177.291 171.427 212.571 1.00 88.10  ? 120 HIS C CG    1 
ATOM 3344 N ND1   . HIS C 3 120 ? 177.874 170.437 213.330 1.00 87.90  ? 120 HIS C ND1   1 
ATOM 3345 C CD2   . HIS C 3 120 ? 177.021 170.870 211.368 1.00 88.22  ? 120 HIS C CD2   1 
ATOM 3346 C CE1   . HIS C 3 120 ? 177.959 169.330 212.615 1.00 88.58  ? 120 HIS C CE1   1 
ATOM 3347 N NE2   . HIS C 3 120 ? 177.448 169.566 211.420 1.00 87.25  ? 120 HIS C NE2   1 
ATOM 3348 N N     . GLU C 3 121 ? 178.688 175.616 212.506 1.00 90.62  ? 121 GLU C N     1 
ATOM 3349 C CA    . GLU C 3 121 ? 178.451 177.026 212.239 1.00 89.21  ? 121 GLU C CA    1 
ATOM 3350 C C     . GLU C 3 121 ? 177.173 177.169 211.427 1.00 92.87  ? 121 GLU C C     1 
ATOM 3351 O O     . GLU C 3 121 ? 177.156 176.888 210.225 1.00 96.13  ? 121 GLU C O     1 
ATOM 3352 C CB    . GLU C 3 121 ? 179.632 177.638 211.489 1.00 92.28  ? 121 GLU C CB    1 
ATOM 3353 C CG    . GLU C 3 121 ? 180.933 176.873 211.662 1.00 99.36  ? 121 GLU C CG    1 
ATOM 3354 C CD    . GLU C 3 121 ? 182.124 177.602 211.072 1.00 101.77 ? 121 GLU C CD    1 
ATOM 3355 O OE1   . GLU C 3 121 ? 183.271 177.226 211.394 1.00 99.85  ? 121 GLU C OE1   1 
ATOM 3356 O OE2   . GLU C 3 121 ? 181.915 178.551 210.288 1.00 99.51  ? 121 GLU C OE2   1 
ATOM 3357 N N     . ILE C 3 122 ? 176.110 177.606 212.081 1.00 81.01  ? 122 ILE C N     1 
ATOM 3358 C CA    . ILE C 3 122 ? 174.791 177.658 211.470 1.00 78.70  ? 122 ILE C CA    1 
ATOM 3359 C C     . ILE C 3 122 ? 174.765 178.770 210.438 1.00 81.51  ? 122 ILE C C     1 
ATOM 3360 O O     . ILE C 3 122 ? 175.591 179.688 210.454 1.00 89.81  ? 122 ILE C O     1 
ATOM 3361 C CB    . ILE C 3 122 ? 173.685 177.865 212.522 1.00 74.96  ? 122 ILE C CB    1 
ATOM 3362 C CG1   . ILE C 3 122 ? 173.592 179.344 212.898 1.00 76.56  ? 122 ILE C CG1   1 
ATOM 3363 C CG2   . ILE C 3 122 ? 173.950 177.004 213.736 1.00 82.07  ? 122 ILE C CG2   1 
ATOM 3364 C CD1   . ILE C 3 122 ? 172.362 179.701 213.684 1.00 81.30  ? 122 ILE C CD1   1 
ATOM 3365 N N     . PHE C 3 123 ? 173.811 178.678 209.522 1.00 67.98  ? 123 PHE C N     1 
ATOM 3366 C CA    . PHE C 3 123 ? 173.595 179.700 208.514 1.00 64.32  ? 123 PHE C CA    1 
ATOM 3367 C C     . PHE C 3 123 ? 172.238 180.338 208.761 1.00 62.68  ? 123 PHE C C     1 
ATOM 3368 O O     . PHE C 3 123 ? 171.270 179.650 209.086 1.00 69.50  ? 123 PHE C O     1 
ATOM 3369 C CB    . PHE C 3 123 ? 173.677 179.102 207.106 1.00 69.55  ? 123 PHE C CB    1 
ATOM 3370 C CG    . PHE C 3 123 ? 173.557 180.117 206.007 1.00 68.40  ? 123 PHE C CG    1 
ATOM 3371 C CD1   . PHE C 3 123 ? 174.654 180.428 205.232 1.00 74.16  ? 123 PHE C CD1   1 
ATOM 3372 C CD2   . PHE C 3 123 ? 172.350 180.734 205.724 1.00 70.37  ? 123 PHE C CD2   1 
ATOM 3373 C CE1   . PHE C 3 123 ? 174.562 181.359 204.228 1.00 79.05  ? 123 PHE C CE1   1 
ATOM 3374 C CE2   . PHE C 3 123 ? 172.254 181.664 204.723 1.00 75.40  ? 123 PHE C CE2   1 
ATOM 3375 C CZ    . PHE C 3 123 ? 173.361 181.977 203.976 1.00 79.75  ? 123 PHE C CZ    1 
ATOM 3376 N N     . VAL C 3 124 ? 172.171 181.653 208.607 1.00 54.11  ? 124 VAL C N     1 
ATOM 3377 C CA    . VAL C 3 124 ? 170.965 182.416 208.887 1.00 52.80  ? 124 VAL C CA    1 
ATOM 3378 C C     . VAL C 3 124 ? 170.628 183.283 207.685 1.00 58.60  ? 124 VAL C C     1 
ATOM 3379 O O     . VAL C 3 124 ? 171.513 183.904 207.087 1.00 73.97  ? 124 VAL C O     1 
ATOM 3380 C CB    . VAL C 3 124 ? 171.137 183.275 210.153 1.00 59.12  ? 124 VAL C CB    1 
ATOM 3381 C CG1   . VAL C 3 124 ? 170.023 184.284 210.270 1.00 63.34  ? 124 VAL C CG1   1 
ATOM 3382 C CG2   . VAL C 3 124 ? 171.174 182.383 211.374 1.00 70.62  ? 124 VAL C CG2   1 
ATOM 3383 N N     . ASP C 3 125 ? 169.349 183.316 207.328 1.00 63.78  ? 125 ASP C N     1 
ATOM 3384 C CA    . ASP C 3 125 ? 168.839 184.164 206.258 1.00 59.05  ? 125 ASP C CA    1 
ATOM 3385 C C     . ASP C 3 125 ? 167.366 184.440 206.542 1.00 67.40  ? 125 ASP C C     1 
ATOM 3386 O O     . ASP C 3 125 ? 166.808 183.951 207.529 1.00 81.59  ? 125 ASP C O     1 
ATOM 3387 C CB    . ASP C 3 125 ? 169.052 183.500 204.895 1.00 69.13  ? 125 ASP C CB    1 
ATOM 3388 C CG    . ASP C 3 125 ? 169.246 184.506 203.786 1.00 83.01  ? 125 ASP C CG    1 
ATOM 3389 O OD1   . ASP C 3 125 ? 168.741 185.638 203.923 1.00 88.53  ? 125 ASP C OD1   1 
ATOM 3390 O OD2   . ASP C 3 125 ? 169.898 184.167 202.776 1.00 77.92  ? 125 ASP C OD2   1 
ATOM 3391 N N     . TYR C 3 126 ? 166.731 185.232 205.684 1.00 61.65  ? 126 TYR C N     1 
ATOM 3392 C CA    . TYR C 3 126 ? 165.288 185.389 205.748 1.00 76.49  ? 126 TYR C CA    1 
ATOM 3393 C C     . TYR C 3 126 ? 164.611 184.208 205.057 1.00 81.98  ? 126 TYR C C     1 
ATOM 3394 O O     . TYR C 3 126 ? 165.262 183.301 204.533 1.00 82.50  ? 126 TYR C O     1 
ATOM 3395 C CB    . TYR C 3 126 ? 164.839 186.692 205.093 1.00 78.95  ? 126 TYR C CB    1 
ATOM 3396 C CG    . TYR C 3 126 ? 165.056 187.944 205.901 1.00 71.61  ? 126 TYR C CG    1 
ATOM 3397 C CD1   . TYR C 3 126 ? 164.503 188.088 207.161 1.00 71.23  ? 126 TYR C CD1   1 
ATOM 3398 C CD2   . TYR C 3 126 ? 165.769 189.008 205.375 1.00 77.35  ? 126 TYR C CD2   1 
ATOM 3399 C CE1   . TYR C 3 126 ? 164.688 189.245 207.889 1.00 73.49  ? 126 TYR C CE1   1 
ATOM 3400 C CE2   . TYR C 3 126 ? 165.953 190.167 206.091 1.00 72.53  ? 126 TYR C CE2   1 
ATOM 3401 C CZ    . TYR C 3 126 ? 165.416 190.280 207.347 1.00 73.78  ? 126 TYR C CZ    1 
ATOM 3402 O OH    . TYR C 3 126 ? 165.606 191.439 208.060 1.00 81.89  ? 126 TYR C OH    1 
ATOM 3403 N N     . GLU C 3 127 ? 163.281 184.220 205.046 1.00 86.38  ? 127 GLU C N     1 
ATOM 3404 C CA    . GLU C 3 127 ? 162.523 183.270 204.244 1.00 84.87  ? 127 GLU C CA    1 
ATOM 3405 C C     . GLU C 3 127 ? 162.287 183.882 202.870 1.00 90.66  ? 127 GLU C C     1 
ATOM 3406 O O     . GLU C 3 127 ? 161.647 184.933 202.756 1.00 95.73  ? 127 GLU C O     1 
ATOM 3407 C CB    . GLU C 3 127 ? 161.197 182.924 204.914 1.00 86.47  ? 127 GLU C CB    1 
ATOM 3408 C CG    . GLU C 3 127 ? 160.472 181.757 204.267 1.00 91.80  ? 127 GLU C CG    1 
ATOM 3409 C CD    . GLU C 3 127 ? 158.967 181.906 204.309 1.00 91.15  ? 127 GLU C CD    1 
ATOM 3410 O OE1   . GLU C 3 127 ? 158.432 182.291 205.367 1.00 92.33  ? 127 GLU C OE1   1 
ATOM 3411 O OE2   . GLU C 3 127 ? 158.313 181.631 203.284 1.00 91.07  ? 127 GLU C OE2   1 
ATOM 3412 N N     . LEU C 3 128 ? 162.808 183.238 201.831 1.00 83.99  ? 128 LEU C N     1 
ATOM 3413 C CA    . LEU C 3 128 ? 162.811 183.814 200.495 1.00 83.86  ? 128 LEU C CA    1 
ATOM 3414 C C     . LEU C 3 128 ? 161.783 183.185 199.561 1.00 85.09  ? 128 LEU C C     1 
ATOM 3415 O O     . LEU C 3 128 ? 161.835 183.427 198.353 1.00 89.81  ? 128 LEU C O     1 
ATOM 3416 C CB    . LEU C 3 128 ? 164.209 183.706 199.890 1.00 77.79  ? 128 LEU C CB    1 
ATOM 3417 C CG    . LEU C 3 128 ? 165.261 184.584 200.566 1.00 76.43  ? 128 LEU C CG    1 
ATOM 3418 C CD1   . LEU C 3 128 ? 166.546 184.589 199.762 1.00 80.83  ? 128 LEU C CD1   1 
ATOM 3419 C CD2   . LEU C 3 128 ? 164.739 185.996 200.753 1.00 82.33  ? 128 LEU C CD2   1 
ATOM 3420 N N     . GLU C 3 129 ? 160.852 182.388 200.081 1.00 76.22  ? 129 GLU C N     1 
ATOM 3421 C CA    . GLU C 3 129 ? 159.831 181.806 199.217 1.00 72.73  ? 129 GLU C CA    1 
ATOM 3422 C C     . GLU C 3 129 ? 158.793 182.842 198.821 1.00 76.08  ? 129 GLU C C     1 
ATOM 3423 O O     . GLU C 3 129 ? 158.604 183.133 197.635 1.00 76.90  ? 129 GLU C O     1 
ATOM 3424 C CB    . GLU C 3 129 ? 159.159 180.629 199.912 1.00 71.84  ? 129 GLU C CB    1 
ATOM 3425 C CG    . GLU C 3 129 ? 160.049 179.442 200.071 1.00 79.40  ? 129 GLU C CG    1 
ATOM 3426 C CD    . GLU C 3 129 ? 159.698 178.625 201.283 1.00 78.30  ? 129 GLU C CD    1 
ATOM 3427 O OE1   . GLU C 3 129 ? 159.165 179.213 202.242 1.00 79.27  ? 129 GLU C OE1   1 
ATOM 3428 O OE2   . GLU C 3 129 ? 159.951 177.403 201.278 1.00 75.16  ? 129 GLU C OE2   1 
ATOM 3429 N N     . ARG C 3 130 ? 158.104 183.411 199.806 1.00 90.10  ? 130 ARG C N     1 
ATOM 3430 C CA    . ARG C 3 130 ? 157.020 184.347 199.561 1.00 94.31  ? 130 ARG C CA    1 
ATOM 3431 C C     . ARG C 3 130 ? 157.499 185.790 199.529 1.00 95.81  ? 130 ARG C C     1 
ATOM 3432 O O     . ARG C 3 130 ? 156.681 186.711 199.622 1.00 98.30  ? 130 ARG C O     1 
ATOM 3433 C CB    . ARG C 3 130 ? 155.930 184.162 200.616 1.00 91.80  ? 130 ARG C CB    1 
ATOM 3434 C CG    . ARG C 3 130 ? 155.332 182.765 200.618 1.00 94.09  ? 130 ARG C CG    1 
ATOM 3435 C CD    . ARG C 3 130 ? 154.593 182.468 201.908 1.00 93.74  ? 130 ARG C CD    1 
ATOM 3436 N NE    . ARG C 3 130 ? 155.503 182.282 203.030 1.00 95.06  ? 130 ARG C NE    1 
ATOM 3437 C CZ    . ARG C 3 130 ? 155.121 182.218 204.297 1.00 96.24  ? 130 ARG C CZ    1 
ATOM 3438 N NH1   . ARG C 3 130 ? 153.848 182.319 204.640 1.00 97.21  ? 130 ARG C NH1   1 
ATOM 3439 N NH2   . ARG C 3 130 ? 156.038 182.045 205.243 1.00 93.93  ? 130 ARG C NH2   1 
ATOM 3440 N N     . THR C 3 131 ? 158.794 186.003 199.407 1.00 86.46  ? 131 THR C N     1 
ATOM 3441 C CA    . THR C 3 131 ? 159.348 187.348 199.328 1.00 91.09  ? 131 THR C CA    1 
ATOM 3442 C C     . THR C 3 131 ? 160.264 187.545 198.131 1.00 93.58  ? 131 THR C C     1 
ATOM 3443 O O     . THR C 3 131 ? 160.260 188.623 197.533 1.00 92.22  ? 131 THR C O     1 
ATOM 3444 C CB    . THR C 3 131 ? 160.107 187.674 200.618 1.00 92.13  ? 131 THR C CB    1 
ATOM 3445 O OG1   . THR C 3 131 ? 160.762 186.493 201.097 1.00 89.52  ? 131 THR C OG1   1 
ATOM 3446 C CG2   . THR C 3 131 ? 159.145 188.179 201.680 1.00 91.89  ? 131 THR C CG2   1 
ATOM 3447 N N     . LEU C 3 132 ? 161.043 186.533 197.763 1.00 83.06  ? 132 LEU C N     1 
ATOM 3448 C CA    . LEU C 3 132 ? 161.969 186.631 196.643 1.00 77.13  ? 132 LEU C CA    1 
ATOM 3449 C C     . LEU C 3 132 ? 161.277 186.135 195.380 1.00 78.14  ? 132 LEU C C     1 
ATOM 3450 O O     . LEU C 3 132 ? 160.926 184.954 195.283 1.00 79.05  ? 132 LEU C O     1 
ATOM 3451 C CB    . LEU C 3 132 ? 163.235 185.825 196.920 1.00 72.95  ? 132 LEU C CB    1 
ATOM 3452 C CG    . LEU C 3 132 ? 164.466 186.139 196.078 1.00 76.47  ? 132 LEU C CG    1 
ATOM 3453 C CD1   . LEU C 3 132 ? 165.114 187.418 196.565 1.00 77.65  ? 132 LEU C CD1   1 
ATOM 3454 C CD2   . LEU C 3 132 ? 165.444 184.990 196.157 1.00 77.46  ? 132 LEU C CD2   1 
ATOM 3455 N N     . LYS C 3 133 ? 161.091 187.035 194.417 1.00 75.74  ? 133 LYS C N     1 
ATOM 3456 C CA    . LYS C 3 133 ? 160.357 186.702 193.206 1.00 73.09  ? 133 LYS C CA    1 
ATOM 3457 C C     . LYS C 3 133 ? 161.065 185.600 192.432 1.00 70.18  ? 133 LYS C C     1 
ATOM 3458 O O     . LYS C 3 133 ? 162.285 185.632 192.256 1.00 69.83  ? 133 LYS C O     1 
ATOM 3459 C CB    . LYS C 3 133 ? 160.200 187.942 192.330 1.00 74.49  ? 133 LYS C CB    1 
ATOM 3460 C CG    . LYS C 3 133 ? 159.018 188.815 192.704 1.00 76.17  ? 133 LYS C CG    1 
ATOM 3461 C CD    . LYS C 3 133 ? 158.743 189.857 191.634 1.00 80.33  ? 133 LYS C CD    1 
ATOM 3462 C CE    . LYS C 3 133 ? 159.962 190.728 191.378 1.00 81.72  ? 133 LYS C CE    1 
ATOM 3463 N NZ    . LYS C 3 133 ? 160.625 191.158 192.640 1.00 75.08  ? 133 LYS C NZ    1 
ATOM 3464 N N     . GLY C 3 134 ? 160.292 184.622 191.972 1.00 69.48  ? 134 GLY C N     1 
ATOM 3465 C CA    . GLY C 3 134 ? 160.850 183.545 191.186 1.00 67.24  ? 134 GLY C CA    1 
ATOM 3466 C C     . GLY C 3 134 ? 161.782 182.630 191.937 1.00 73.34  ? 134 GLY C C     1 
ATOM 3467 O O     . GLY C 3 134 ? 162.567 181.917 191.308 1.00 69.57  ? 134 GLY C O     1 
ATOM 3468 N N     . TRP C 3 135 ? 161.719 182.620 193.266 1.00 66.87  ? 135 TRP C N     1 
ATOM 3469 C CA    . TRP C 3 135 ? 162.626 181.789 194.044 1.00 53.78  ? 135 TRP C CA    1 
ATOM 3470 C C     . TRP C 3 135 ? 162.387 180.317 193.748 1.00 51.51  ? 135 TRP C C     1 
ATOM 3471 O O     . TRP C 3 135 ? 161.242 179.867 193.665 1.00 57.32  ? 135 TRP C O     1 
ATOM 3472 C CB    . TRP C 3 135 ? 162.445 182.050 195.536 1.00 57.41  ? 135 TRP C CB    1 
ATOM 3473 C CG    . TRP C 3 135 ? 162.941 180.910 196.364 1.00 58.49  ? 135 TRP C CG    1 
ATOM 3474 C CD1   . TRP C 3 135 ? 162.190 179.957 196.982 1.00 56.58  ? 135 TRP C CD1   1 
ATOM 3475 C CD2   . TRP C 3 135 ? 164.306 180.592 196.647 1.00 59.97  ? 135 TRP C CD2   1 
ATOM 3476 N NE1   . TRP C 3 135 ? 163.003 179.067 197.636 1.00 53.83  ? 135 TRP C NE1   1 
ATOM 3477 C CE2   . TRP C 3 135 ? 164.307 179.437 197.445 1.00 61.18  ? 135 TRP C CE2   1 
ATOM 3478 C CE3   . TRP C 3 135 ? 165.526 181.174 196.307 1.00 63.05  ? 135 TRP C CE3   1 
ATOM 3479 C CZ2   . TRP C 3 135 ? 165.479 178.855 197.906 1.00 68.59  ? 135 TRP C CZ2   1 
ATOM 3480 C CZ3   . TRP C 3 135 ? 166.685 180.595 196.764 1.00 51.66  ? 135 TRP C CZ3   1 
ATOM 3481 C CH2   . TRP C 3 135 ? 166.656 179.449 197.555 1.00 59.17  ? 135 TRP C CH2   1 
ATOM 3482 N N     . ILE C 3 136 ? 163.473 179.568 193.594 1.00 64.60  ? 136 ILE C N     1 
ATOM 3483 C CA    . ILE C 3 136 ? 163.429 178.133 193.345 1.00 62.34  ? 136 ILE C CA    1 
ATOM 3484 C C     . ILE C 3 136 ? 164.338 177.457 194.359 1.00 63.71  ? 136 ILE C C     1 
ATOM 3485 O O     . ILE C 3 136 ? 165.504 177.834 194.478 1.00 73.56  ? 136 ILE C O     1 
ATOM 3486 C CB    . ILE C 3 136 ? 163.867 177.770 191.914 1.00 62.55  ? 136 ILE C CB    1 
ATOM 3487 C CG1   . ILE C 3 136 ? 163.040 178.543 190.891 1.00 64.75  ? 136 ILE C CG1   1 
ATOM 3488 C CG2   . ILE C 3 136 ? 163.719 176.283 191.679 1.00 62.17  ? 136 ILE C CG2   1 
ATOM 3489 C CD1   . ILE C 3 136 ? 161.568 178.267 190.976 1.00 65.94  ? 136 ILE C CD1   1 
ATOM 3490 N N     . PRO C 3 137 ? 163.857 176.468 195.107 1.00 48.18  ? 137 PRO C N     1 
ATOM 3491 C CA    . PRO C 3 137 ? 164.722 175.767 196.056 1.00 42.89  ? 137 PRO C CA    1 
ATOM 3492 C C     . PRO C 3 137 ? 165.711 174.862 195.347 1.00 60.01  ? 137 PRO C C     1 
ATOM 3493 O O     . PRO C 3 137 ? 165.573 174.543 194.166 1.00 78.53  ? 137 PRO C O     1 
ATOM 3494 C CB    . PRO C 3 137 ? 163.736 174.950 196.888 1.00 60.68  ? 137 PRO C CB    1 
ATOM 3495 C CG    . PRO C 3 137 ? 162.612 174.716 195.971 1.00 59.98  ? 137 PRO C CG    1 
ATOM 3496 C CD    . PRO C 3 137 ? 162.481 175.965 195.155 1.00 58.64  ? 137 PRO C CD    1 
ATOM 3497 N N     . ARG C 3 138 ? 166.722 174.438 196.103 1.00 63.28  ? 138 ARG C N     1 
ATOM 3498 C CA    . ARG C 3 138 ? 167.784 173.617 195.533 1.00 70.77  ? 138 ARG C CA    1 
ATOM 3499 C C     . ARG C 3 138 ? 167.273 172.261 195.065 1.00 72.99  ? 138 ARG C C     1 
ATOM 3500 O O     . ARG C 3 138 ? 167.827 171.687 194.122 1.00 77.52  ? 138 ARG C O     1 
ATOM 3501 C CB    . ARG C 3 138 ? 168.904 173.441 196.553 1.00 70.11  ? 138 ARG C CB    1 
ATOM 3502 C CG    . ARG C 3 138 ? 170.059 172.592 196.075 1.00 64.21  ? 138 ARG C CG    1 
ATOM 3503 C CD    . ARG C 3 138 ? 171.357 173.045 196.706 1.00 70.36  ? 138 ARG C CD    1 
ATOM 3504 N NE    . ARG C 3 138 ? 172.093 173.940 195.825 1.00 67.74  ? 138 ARG C NE    1 
ATOM 3505 C CZ    . ARG C 3 138 ? 172.893 173.530 194.853 1.00 73.00  ? 138 ARG C CZ    1 
ATOM 3506 N NH1   . ARG C 3 138 ? 173.086 172.244 194.614 1.00 75.86  ? 138 ARG C NH1   1 
ATOM 3507 N NH2   . ARG C 3 138 ? 173.514 174.432 194.102 1.00 80.45  ? 138 ARG C NH2   1 
ATOM 3508 N N     . ARG C 3 139 ? 166.226 171.732 195.702 1.00 72.75  ? 139 ARG C N     1 
ATOM 3509 C CA    . ARG C 3 139 ? 165.705 170.432 195.294 1.00 71.83  ? 139 ARG C CA    1 
ATOM 3510 C C     . ARG C 3 139 ? 165.180 170.477 193.866 1.00 76.03  ? 139 ARG C C     1 
ATOM 3511 O O     . ARG C 3 139 ? 165.390 169.540 193.089 1.00 89.80  ? 139 ARG C O     1 
ATOM 3512 C CB    . ARG C 3 139 ? 164.611 169.974 196.258 1.00 76.65  ? 139 ARG C CB    1 
ATOM 3513 C CG    . ARG C 3 139 ? 163.490 170.971 196.447 1.00 72.30  ? 139 ARG C CG    1 
ATOM 3514 C CD    . ARG C 3 139 ? 162.490 170.485 197.463 1.00 70.92  ? 139 ARG C CD    1 
ATOM 3515 N NE    . ARG C 3 139 ? 161.408 171.442 197.634 1.00 76.98  ? 139 ARG C NE    1 
ATOM 3516 C CZ    . ARG C 3 139 ? 160.253 171.378 196.989 1.00 76.83  ? 139 ARG C CZ    1 
ATOM 3517 N NH1   . ARG C 3 139 ? 159.989 170.397 196.144 1.00 77.10  ? 139 ARG C NH1   1 
ATOM 3518 N NH2   . ARG C 3 139 ? 159.337 172.317 197.204 1.00 75.75  ? 139 ARG C NH2   1 
ATOM 3519 N N     . LEU C 3 140 ? 164.502 171.562 193.503 1.00 80.17  ? 140 LEU C N     1 
ATOM 3520 C CA    . LEU C 3 140 ? 164.016 171.790 192.149 1.00 73.14  ? 140 LEU C CA    1 
ATOM 3521 C C     . LEU C 3 140 ? 165.106 172.272 191.208 1.00 72.99  ? 140 LEU C C     1 
ATOM 3522 O O     . LEU C 3 140 ? 164.792 172.741 190.111 1.00 77.68  ? 140 LEU C O     1 
ATOM 3523 C CB    . LEU C 3 140 ? 162.875 172.809 192.168 1.00 61.98  ? 140 LEU C CB    1 
ATOM 3524 C CG    . LEU C 3 140 ? 161.449 172.273 192.117 1.00 59.83  ? 140 LEU C CG    1 
ATOM 3525 C CD1   . LEU C 3 140 ? 161.172 171.443 193.333 1.00 70.20  ? 140 LEU C CD1   1 
ATOM 3526 C CD2   . LEU C 3 140 ? 160.470 173.422 192.046 1.00 64.02  ? 140 LEU C CD2   1 
ATOM 3527 N N     . GLY C 3 141 ? 166.368 172.182 191.613 1.00 74.12  ? 141 GLY C N     1 
ATOM 3528 C CA    . GLY C 3 141 ? 167.447 172.750 190.836 1.00 74.56  ? 141 GLY C CA    1 
ATOM 3529 C C     . GLY C 3 141 ? 167.594 174.221 191.155 1.00 71.06  ? 141 GLY C C     1 
ATOM 3530 O O     . GLY C 3 141 ? 166.625 174.978 191.058 1.00 74.82  ? 141 GLY C O     1 
ATOM 3531 N N     . GLY C 3 142 ? 168.788 174.641 191.547 1.00 72.24  ? 142 GLY C N     1 
ATOM 3532 C CA    . GLY C 3 142 ? 168.986 176.032 191.891 1.00 78.08  ? 142 GLY C CA    1 
ATOM 3533 C C     . GLY C 3 142 ? 169.192 176.267 193.371 1.00 89.60  ? 142 GLY C C     1 
ATOM 3534 O O     . GLY C 3 142 ? 170.108 175.704 193.978 1.00 88.98  ? 142 GLY C O     1 
ATOM 3535 N N     . GLY C 3 143 ? 168.337 177.088 193.971 1.00 86.94  ? 143 GLY C N     1 
ATOM 3536 C CA    . GLY C 3 143 ? 168.616 177.499 195.328 1.00 76.23  ? 143 GLY C CA    1 
ATOM 3537 C C     . GLY C 3 143 ? 169.747 178.511 195.340 1.00 74.61  ? 143 GLY C C     1 
ATOM 3538 O O     . GLY C 3 143 ? 170.016 179.197 194.351 1.00 86.87  ? 143 GLY C O     1 
ATOM 3539 N N     . LEU C 3 144 ? 170.424 178.604 196.479 1.00 48.99  ? 144 LEU C N     1 
ATOM 3540 C CA    . LEU C 3 144 ? 171.551 179.510 196.628 1.00 63.04  ? 144 LEU C CA    1 
ATOM 3541 C C     . LEU C 3 144 ? 172.696 178.735 197.264 1.00 64.32  ? 144 LEU C C     1 
ATOM 3542 O O     . LEU C 3 144 ? 172.653 177.507 197.375 1.00 68.48  ? 144 LEU C O     1 
ATOM 3543 C CB    . LEU C 3 144 ? 171.160 180.745 197.448 1.00 65.12  ? 144 LEU C CB    1 
ATOM 3544 C CG    . LEU C 3 144 ? 170.135 181.679 196.813 1.00 59.27  ? 144 LEU C CG    1 
ATOM 3545 C CD1   . LEU C 3 144 ? 169.703 182.740 197.798 1.00 69.38  ? 144 LEU C CD1   1 
ATOM 3546 C CD2   . LEU C 3 144 ? 170.706 182.311 195.572 1.00 70.59  ? 144 LEU C CD2   1 
ATOM 3547 N N     . GLY C 3 145 ? 173.730 179.459 197.675 1.00 71.51  ? 145 GLY C N     1 
ATOM 3548 C CA    . GLY C 3 145 ? 174.841 178.848 198.370 1.00 76.94  ? 145 GLY C CA    1 
ATOM 3549 C C     . GLY C 3 145 ? 175.518 177.772 197.557 1.00 73.61  ? 145 GLY C C     1 
ATOM 3550 O O     . GLY C 3 145 ? 176.219 178.068 196.590 1.00 84.99  ? 145 GLY C O     1 
ATOM 3551 N N     . GLY C 3 146 ? 175.308 176.521 197.934 1.00 65.87  ? 146 GLY C N     1 
ATOM 3552 C CA    . GLY C 3 146 ? 175.964 175.430 197.258 1.00 59.77  ? 146 GLY C CA    1 
ATOM 3553 C C     . GLY C 3 146 ? 177.401 175.289 197.723 1.00 67.34  ? 146 GLY C C     1 
ATOM 3554 O O     . GLY C 3 146 ? 177.884 175.994 198.606 1.00 67.45  ? 146 GLY C O     1 
ATOM 3555 N N     . LYS C 3 147 ? 178.088 174.339 197.101 1.00 88.46  ? 147 LYS C N     1 
ATOM 3556 C CA    . LYS C 3 147 ? 179.527 174.207 197.258 1.00 88.72  ? 147 LYS C CA    1 
ATOM 3557 C C     . LYS C 3 147 ? 180.132 173.889 195.902 1.00 92.06  ? 147 LYS C C     1 
ATOM 3558 O O     . LYS C 3 147 ? 179.700 172.946 195.234 1.00 93.28  ? 147 LYS C O     1 
ATOM 3559 C CB    . LYS C 3 147 ? 179.886 173.125 198.281 1.00 83.09  ? 147 LYS C CB    1 
ATOM 3560 C CG    . LYS C 3 147 ? 179.871 173.633 199.708 1.00 84.00  ? 147 LYS C CG    1 
ATOM 3561 C CD    . LYS C 3 147 ? 180.008 172.506 200.710 1.00 88.58  ? 147 LYS C CD    1 
ATOM 3562 C CE    . LYS C 3 147 ? 179.870 173.031 202.130 1.00 91.01  ? 147 LYS C CE    1 
ATOM 3563 N NZ    . LYS C 3 147 ? 179.434 171.967 203.073 1.00 92.83  ? 147 LYS C NZ    1 
ATOM 3564 N N     . LYS C 3 148 ? 181.136 174.674 195.507 1.00 93.80  ? 148 LYS C N     1 
ATOM 3565 C CA    . LYS C 3 148 ? 181.760 174.489 194.203 1.00 96.33  ? 148 LYS C CA    1 
ATOM 3566 C C     . LYS C 3 148 ? 182.393 173.112 194.059 1.00 98.80  ? 148 LYS C C     1 
ATOM 3567 O O     . LYS C 3 148 ? 182.666 172.682 192.934 1.00 102.29 ? 148 LYS C O     1 
ATOM 3568 C CB    . LYS C 3 148 ? 182.810 175.573 193.966 1.00 97.26  ? 148 LYS C CB    1 
ATOM 3569 C CG    . LYS C 3 148 ? 183.509 176.044 195.228 1.00 99.68  ? 148 LYS C CG    1 
ATOM 3570 C CD    . LYS C 3 148 ? 184.519 177.134 194.915 1.00 104.18 ? 148 LYS C CD    1 
ATOM 3571 C CE    . LYS C 3 148 ? 183.851 178.342 194.282 1.00 100.24 ? 148 LYS C CE    1 
ATOM 3572 N NZ    . LYS C 3 148 ? 184.796 179.479 194.120 1.00 98.32  ? 148 LYS C NZ    1 
ATOM 3573 N N     . GLU C 3 149 ? 182.642 172.419 195.170 1.00 97.80  ? 149 GLU C N     1 
ATOM 3574 C CA    . GLU C 3 149 ? 183.139 171.052 195.094 1.00 101.34 ? 149 GLU C CA    1 
ATOM 3575 C C     . GLU C 3 149 ? 182.139 170.148 194.386 1.00 100.05 ? 149 GLU C C     1 
ATOM 3576 O O     . GLU C 3 149 ? 182.517 169.326 193.543 1.00 96.29  ? 149 GLU C O     1 
ATOM 3577 C CB    . GLU C 3 149 ? 183.430 170.534 196.503 1.00 100.43 ? 149 GLU C CB    1 
ATOM 3578 C CG    . GLU C 3 149 ? 183.869 169.083 196.577 1.00 100.22 ? 149 GLU C CG    1 
ATOM 3579 C CD    . GLU C 3 149 ? 184.855 168.723 195.492 1.00 106.10 ? 149 GLU C CD    1 
ATOM 3580 O OE1   . GLU C 3 149 ? 185.971 169.282 195.490 1.00 103.16 ? 149 GLU C OE1   1 
ATOM 3581 O OE2   . GLU C 3 149 ? 184.511 167.894 194.630 1.00 108.59 ? 149 GLU C OE2   1 
ATOM 3582 N N     . SER C 3 150 ? 180.856 170.304 194.691 1.00 96.29  ? 150 SER C N     1 
ATOM 3583 C CA    . SER C 3 150 ? 179.834 169.367 194.228 1.00 92.68  ? 150 SER C CA    1 
ATOM 3584 C C     . SER C 3 150 ? 179.335 169.704 192.828 1.00 92.59  ? 150 SER C C     1 
ATOM 3585 O O     . SER C 3 150 ? 178.135 169.749 192.573 1.00 96.31  ? 150 SER C O     1 
ATOM 3586 C CB    . SER C 3 150 ? 178.681 169.347 195.221 1.00 98.46  ? 150 SER C CB    1 
ATOM 3587 O OG    . SER C 3 150 ? 178.996 168.541 196.343 1.00 103.72 ? 150 SER C OG    1 
ATOM 3588 N N     . GLY C 3 151 ? 180.266 169.919 191.904 1.00 102.29 ? 151 GLY C N     1 
ATOM 3589 C CA    . GLY C 3 151 ? 179.949 170.133 190.504 1.00 106.35 ? 151 GLY C CA    1 
ATOM 3590 C C     . GLY C 3 151 ? 178.949 171.222 190.156 1.00 103.80 ? 151 GLY C C     1 
ATOM 3591 O O     . GLY C 3 151 ? 178.585 171.358 188.985 1.00 102.22 ? 151 GLY C O     1 
ATOM 3592 N N     . GLN C 3 152 ? 178.497 172.006 191.132 1.00 94.94  ? 152 GLN C N     1 
ATOM 3593 C CA    . GLN C 3 152 ? 177.539 173.065 190.847 1.00 84.45  ? 152 GLN C CA    1 
ATOM 3594 C C     . GLN C 3 152 ? 177.580 174.090 191.969 1.00 86.01  ? 152 GLN C C     1 
ATOM 3595 O O     . GLN C 3 152 ? 178.101 173.833 193.055 1.00 94.84  ? 152 GLN C O     1 
ATOM 3596 C CB    . GLN C 3 152 ? 176.125 172.510 190.667 1.00 81.10  ? 152 GLN C CB    1 
ATOM 3597 C CG    . GLN C 3 152 ? 175.682 171.549 191.744 1.00 80.94  ? 152 GLN C CG    1 
ATOM 3598 C CD    . GLN C 3 152 ? 174.655 170.559 191.243 1.00 83.75  ? 152 GLN C CD    1 
ATOM 3599 O OE1   . GLN C 3 152 ? 174.931 169.749 190.359 1.00 85.29  ? 152 GLN C OE1   1 
ATOM 3600 N NE2   . GLN C 3 152 ? 173.454 170.632 191.793 1.00 88.60  ? 152 GLN C NE2   1 
ATOM 3601 N N     . LEU C 3 153 ? 177.012 175.259 191.687 1.00 74.79  ? 153 LEU C N     1 
ATOM 3602 C CA    . LEU C 3 153 ? 177.029 176.393 192.599 1.00 70.17  ? 153 LEU C CA    1 
ATOM 3603 C C     . LEU C 3 153 ? 175.928 177.349 192.181 1.00 72.43  ? 153 LEU C C     1 
ATOM 3604 O O     . LEU C 3 153 ? 175.547 177.385 191.010 1.00 89.40  ? 153 LEU C O     1 
ATOM 3605 C CB    . LEU C 3 153 ? 178.386 177.102 192.574 1.00 69.56  ? 153 LEU C CB    1 
ATOM 3606 C CG    . LEU C 3 153 ? 178.831 177.821 193.840 1.00 70.50  ? 153 LEU C CG    1 
ATOM 3607 C CD1   . LEU C 3 153 ? 178.640 176.917 195.015 1.00 77.89  ? 153 LEU C CD1   1 
ATOM 3608 C CD2   . LEU C 3 153 ? 180.281 178.208 193.725 1.00 80.47  ? 153 LEU C CD2   1 
ATOM 3609 N N     . ARG C 3 154 ? 175.418 178.117 193.140 1.00 67.42  ? 154 ARG C N     1 
ATOM 3610 C CA    . ARG C 3 154 ? 174.385 179.112 192.861 1.00 76.04  ? 154 ARG C CA    1 
ATOM 3611 C C     . ARG C 3 154 ? 174.745 180.396 193.589 1.00 76.24  ? 154 ARG C C     1 
ATOM 3612 O O     . ARG C 3 154 ? 174.609 180.478 194.812 1.00 86.72  ? 154 ARG C O     1 
ATOM 3613 C CB    . ARG C 3 154 ? 173.002 178.619 193.284 1.00 79.26  ? 154 ARG C CB    1 
ATOM 3614 C CG    . ARG C 3 154 ? 172.608 177.283 192.692 1.00 76.66  ? 154 ARG C CG    1 
ATOM 3615 C CD    . ARG C 3 154 ? 172.419 177.378 191.192 1.00 82.38  ? 154 ARG C CD    1 
ATOM 3616 N NE    . ARG C 3 154 ? 172.107 176.081 190.609 1.00 82.78  ? 154 ARG C NE    1 
ATOM 3617 C CZ    . ARG C 3 154 ? 173.014 175.171 190.289 1.00 84.94  ? 154 ARG C CZ    1 
ATOM 3618 N NH1   . ARG C 3 154 ? 174.303 175.380 190.491 1.00 88.13  ? 154 ARG C NH1   1 
ATOM 3619 N NH2   . ARG C 3 154 ? 172.619 174.020 189.757 1.00 85.56  ? 154 ARG C NH2   1 
ATOM 3620 N N     . PHE C 3 155 ? 175.181 181.399 192.843 1.00 75.00  ? 155 PHE C N     1 
ATOM 3621 C CA    . PHE C 3 155 ? 175.648 182.639 193.434 1.00 79.52  ? 155 PHE C CA    1 
ATOM 3622 C C     . PHE C 3 155 ? 174.458 183.538 193.747 1.00 79.75  ? 155 PHE C C     1 
ATOM 3623 O O     . PHE C 3 155 ? 173.301 183.123 193.673 1.00 86.39  ? 155 PHE C O     1 
ATOM 3624 C CB    . PHE C 3 155 ? 176.640 183.326 192.503 1.00 84.36  ? 155 PHE C CB    1 
ATOM 3625 C CG    . PHE C 3 155 ? 177.914 182.562 192.308 1.00 86.75  ? 155 PHE C CG    1 
ATOM 3626 C CD1   . PHE C 3 155 ? 177.980 181.519 191.405 1.00 89.63  ? 155 PHE C CD1   1 
ATOM 3627 C CD2   . PHE C 3 155 ? 179.044 182.888 193.029 1.00 84.30  ? 155 PHE C CD2   1 
ATOM 3628 C CE1   . PHE C 3 155 ? 179.146 180.818 191.226 1.00 86.43  ? 155 PHE C CE1   1 
ATOM 3629 C CE2   . PHE C 3 155 ? 180.213 182.191 192.853 1.00 88.73  ? 155 PHE C CE2   1 
ATOM 3630 C CZ    . PHE C 3 155 ? 180.264 181.156 191.950 1.00 89.11  ? 155 PHE C CZ    1 
ATOM 3631 N N     . GLY C 3 156 ? 174.737 184.785 194.110 1.00 83.75  ? 156 GLY C N     1 
ATOM 3632 C CA    . GLY C 3 156 ? 173.700 185.764 194.340 1.00 85.87  ? 156 GLY C CA    1 
ATOM 3633 C C     . GLY C 3 156 ? 173.123 185.782 195.735 1.00 86.04  ? 156 GLY C C     1 
ATOM 3634 O O     . GLY C 3 156 ? 172.338 186.686 196.049 1.00 92.45  ? 156 GLY C O     1 
ATOM 3635 N N     . GLY C 3 157 ? 173.484 184.824 196.587 1.00 77.45  ? 157 GLY C N     1 
ATOM 3636 C CA    . GLY C 3 157 ? 172.979 184.768 197.938 1.00 78.21  ? 157 GLY C CA    1 
ATOM 3637 C C     . GLY C 3 157 ? 173.851 185.547 198.910 1.00 85.94  ? 157 GLY C C     1 
ATOM 3638 O O     . GLY C 3 157 ? 174.856 186.154 198.551 1.00 94.32  ? 157 GLY C O     1 
ATOM 3639 N N     . ARG C 3 158 ? 173.431 185.520 200.175 1.00 85.98  ? 158 ARG C N     1 
ATOM 3640 C CA    . ARG C 3 158 ? 174.230 186.143 201.223 1.00 82.70  ? 158 ARG C CA    1 
ATOM 3641 C C     . ARG C 3 158 ? 175.587 185.464 201.343 1.00 80.16  ? 158 ARG C C     1 
ATOM 3642 O O     . ARG C 3 158 ? 176.610 186.130 201.538 1.00 83.82  ? 158 ARG C O     1 
ATOM 3643 C CB    . ARG C 3 158 ? 173.483 186.094 202.556 1.00 77.49  ? 158 ARG C CB    1 
ATOM 3644 C CG    . ARG C 3 158 ? 174.379 186.281 203.762 1.00 78.89  ? 158 ARG C CG    1 
ATOM 3645 C CD    . ARG C 3 158 ? 173.630 186.115 205.067 1.00 74.34  ? 158 ARG C CD    1 
ATOM 3646 N NE    . ARG C 3 158 ? 174.195 186.963 206.108 1.00 78.72  ? 158 ARG C NE    1 
ATOM 3647 C CZ    . ARG C 3 158 ? 173.896 186.872 207.396 1.00 83.58  ? 158 ARG C CZ    1 
ATOM 3648 N NH1   . ARG C 3 158 ? 173.041 185.969 207.845 1.00 83.89  ? 158 ARG C NH1   1 
ATOM 3649 N NH2   . ARG C 3 158 ? 174.471 187.708 208.256 1.00 91.87  ? 158 ARG C NH2   1 
ATOM 3650 N N     . ASP C 3 159 ? 175.615 184.137 201.223 1.00 93.53  ? 159 ASP C N     1 
ATOM 3651 C CA    . ASP C 3 159 ? 176.876 183.413 201.315 1.00 98.87  ? 159 ASP C CA    1 
ATOM 3652 C C     . ASP C 3 159 ? 177.819 183.781 200.177 1.00 104.03 ? 159 ASP C C     1 
ATOM 3653 O O     . ASP C 3 159 ? 179.016 183.993 200.401 1.00 110.80 ? 159 ASP C O     1 
ATOM 3654 C CB    . ASP C 3 159 ? 176.610 181.910 201.323 1.00 102.23 ? 159 ASP C CB    1 
ATOM 3655 C CG    . ASP C 3 159 ? 177.574 181.155 202.208 1.00 108.90 ? 159 ASP C CG    1 
ATOM 3656 O OD1   . ASP C 3 159 ? 178.157 181.781 203.116 1.00 111.43 ? 159 ASP C OD1   1 
ATOM 3657 O OD2   . ASP C 3 159 ? 177.747 179.937 201.998 1.00 109.57 ? 159 ASP C OD2   1 
ATOM 3658 N N     . ARG C 3 160 ? 177.302 183.867 198.950 1.00 93.88  ? 160 ARG C N     1 
ATOM 3659 C CA    . ARG C 3 160 ? 178.106 184.144 197.758 1.00 91.74  ? 160 ARG C CA    1 
ATOM 3660 C C     . ARG C 3 160 ? 177.466 185.279 196.971 1.00 97.19  ? 160 ARG C C     1 
ATOM 3661 O O     . ARG C 3 160 ? 176.758 185.041 195.983 1.00 99.27  ? 160 ARG C O     1 
ATOM 3662 C CB    . ARG C 3 160 ? 178.240 182.898 196.883 1.00 89.91  ? 160 ARG C CB    1 
ATOM 3663 C CG    . ARG C 3 160 ? 178.934 181.730 197.545 1.00 88.94  ? 160 ARG C CG    1 
ATOM 3664 C CD    . ARG C 3 160 ? 179.759 180.957 196.536 1.00 87.87  ? 160 ARG C CD    1 
ATOM 3665 N NE    . ARG C 3 160 ? 179.790 179.529 196.827 1.00 92.67  ? 160 ARG C NE    1 
ATOM 3666 C CZ    . ARG C 3 160 ? 180.543 178.970 197.764 1.00 97.37  ? 160 ARG C CZ    1 
ATOM 3667 N NH1   . ARG C 3 160 ? 181.351 179.691 198.523 1.00 96.82  ? 160 ARG C NH1   1 
ATOM 3668 N NH2   . ARG C 3 160 ? 180.489 177.653 197.939 1.00 95.75  ? 160 ARG C NH2   1 
ATOM 3669 N N     . PRO C 3 161 ? 177.690 186.526 197.375 1.00 90.81  ? 161 PRO C N     1 
ATOM 3670 C CA    . PRO C 3 161 ? 177.143 187.652 196.614 1.00 90.57  ? 161 PRO C CA    1 
ATOM 3671 C C     . PRO C 3 161 ? 177.800 187.764 195.248 1.00 98.04  ? 161 PRO C C     1 
ATOM 3672 O O     . PRO C 3 161 ? 178.875 187.216 194.993 1.00 100.56 ? 161 PRO C O     1 
ATOM 3673 C CB    . PRO C 3 161 ? 177.465 188.870 197.487 1.00 88.91  ? 161 PRO C CB    1 
ATOM 3674 C CG    . PRO C 3 161 ? 177.776 188.315 198.835 1.00 92.82  ? 161 PRO C CG    1 
ATOM 3675 C CD    . PRO C 3 161 ? 178.387 186.975 198.588 1.00 90.89  ? 161 PRO C CD    1 
ATOM 3676 N N     . PHE C 3 162 ? 177.123 188.478 194.355 1.00 115.58 ? 162 PHE C N     1 
ATOM 3677 C CA    . PHE C 3 162 ? 177.615 188.636 192.996 1.00 110.65 ? 162 PHE C CA    1 
ATOM 3678 C C     . PHE C 3 162 ? 178.893 189.469 192.964 1.00 115.82 ? 162 PHE C C     1 
ATOM 3679 O O     . PHE C 3 162 ? 179.077 190.401 193.752 1.00 118.26 ? 162 PHE C O     1 
ATOM 3680 C CB    . PHE C 3 162 ? 176.552 189.288 192.115 1.00 108.43 ? 162 PHE C CB    1 
ATOM 3681 C CG    . PHE C 3 162 ? 175.504 188.335 191.631 1.00 113.25 ? 162 PHE C CG    1 
ATOM 3682 C CD1   . PHE C 3 162 ? 175.831 187.025 191.329 1.00 115.18 ? 162 PHE C CD1   1 
ATOM 3683 C CD2   . PHE C 3 162 ? 174.195 188.752 191.463 1.00 113.99 ? 162 PHE C CD2   1 
ATOM 3684 C CE1   . PHE C 3 162 ? 174.872 186.146 190.880 1.00 114.38 ? 162 PHE C CE1   1 
ATOM 3685 C CE2   . PHE C 3 162 ? 173.231 187.878 191.013 1.00 113.79 ? 162 PHE C CE2   1 
ATOM 3686 C CZ    . PHE C 3 162 ? 173.569 186.574 190.721 1.00 115.07 ? 162 PHE C CZ    1 
ATOM 3687 N N     . ARG C 3 163 ? 179.779 189.123 192.028 1.00 144.11 ? 163 ARG C N     1 
ATOM 3688 C CA    . ARG C 3 163 ? 181.040 189.839 191.832 1.00 146.85 ? 163 ARG C CA    1 
ATOM 3689 C C     . ARG C 3 163 ? 180.802 191.041 190.916 1.00 147.32 ? 163 ARG C C     1 
ATOM 3690 O O     . ARG C 3 163 ? 181.296 191.127 189.790 1.00 144.00 ? 163 ARG C O     1 
ATOM 3691 C CB    . ARG C 3 163 ? 182.097 188.903 191.264 1.00 147.32 ? 163 ARG C CB    1 
ATOM 3692 C CG    . ARG C 3 163 ? 183.527 189.391 191.425 1.00 147.40 ? 163 ARG C CG    1 
ATOM 3693 C CD    . ARG C 3 163 ? 184.503 188.470 190.708 1.00 146.89 ? 163 ARG C CD    1 
ATOM 3694 N NE    . ARG C 3 163 ? 184.504 187.127 191.276 1.00 150.80 ? 163 ARG C NE    1 
ATOM 3695 C CZ    . ARG C 3 163 ? 185.137 186.782 192.389 1.00 148.46 ? 163 ARG C CZ    1 
ATOM 3696 N NH1   . ARG C 3 163 ? 185.842 187.660 193.084 1.00 147.56 ? 163 ARG C NH1   1 
ATOM 3697 N NH2   . ARG C 3 163 ? 185.062 185.525 192.815 1.00 144.80 ? 163 ARG C NH2   1 
ATOM 3698 N N     . LYS C 3 164 ? 180.018 191.984 191.426 1.00 136.65 ? 164 LYS C N     1 
ATOM 3699 C CA    . LYS C 3 164 ? 179.675 193.182 190.670 1.00 135.68 ? 164 LYS C CA    1 
ATOM 3700 C C     . LYS C 3 164 ? 180.753 194.251 190.816 1.00 135.60 ? 164 LYS C C     1 
ATOM 3701 O O     . LYS C 3 164 ? 180.864 195.157 189.990 1.00 133.64 ? 164 LYS C O     1 
ATOM 3702 C CB    . LYS C 3 164 ? 178.323 193.733 191.126 1.00 131.82 ? 164 LYS C CB    1 
ATOM 3703 C CG    . LYS C 3 164 ? 177.177 192.742 191.014 1.00 128.98 ? 164 LYS C CG    1 
ATOM 3704 C CD    . LYS C 3 164 ? 177.047 192.195 189.601 1.00 131.77 ? 164 LYS C CD    1 
ATOM 3705 C CE    . LYS C 3 164 ? 175.694 191.532 189.397 1.00 133.68 ? 164 LYS C CE    1 
ATOM 3706 N NZ    . LYS C 3 164 ? 175.514 191.012 188.016 1.00 129.78 ? 164 LYS C NZ    1 
ATOM 3707 N N     . GLU D 4 291 ? 129.185 145.057 168.678 1.00 322.03 ? 291 GLU D N     1 
ATOM 3708 C CA    . GLU D 4 291 ? 129.286 144.460 170.004 1.00 322.05 ? 291 GLU D CA    1 
ATOM 3709 C C     . GLU D 4 291 ? 130.056 145.380 170.943 1.00 322.48 ? 291 GLU D C     1 
ATOM 3710 O O     . GLU D 4 291 ? 129.777 145.436 172.141 1.00 322.84 ? 291 GLU D O     1 
ATOM 3711 C CB    . GLU D 4 291 ? 129.959 143.086 169.924 1.00 321.89 ? 291 GLU D CB    1 
ATOM 3712 C CG    . GLU D 4 291 ? 130.316 142.467 171.270 1.00 321.86 ? 291 GLU D CG    1 
ATOM 3713 C CD    . GLU D 4 291 ? 131.701 142.859 171.752 1.00 321.88 ? 291 GLU D CD    1 
ATOM 3714 O OE1   . GLU D 4 291 ? 132.665 142.720 170.972 1.00 322.07 ? 291 GLU D OE1   1 
ATOM 3715 O OE2   . GLU D 4 291 ? 131.821 143.315 172.908 1.00 321.60 ? 291 GLU D OE2   1 
ATOM 3716 N N     . GLN D 4 292 ? 131.027 146.103 170.382 1.00 324.19 ? 292 GLN D N     1 
ATOM 3717 C CA    . GLN D 4 292 ? 131.892 146.950 171.197 1.00 324.07 ? 292 GLN D CA    1 
ATOM 3718 C C     . GLN D 4 292 ? 131.088 148.022 171.921 1.00 324.52 ? 292 GLN D C     1 
ATOM 3719 O O     . GLN D 4 292 ? 131.233 148.212 173.134 1.00 324.59 ? 292 GLN D O     1 
ATOM 3720 C CB    . GLN D 4 292 ? 132.974 147.582 170.323 1.00 323.68 ? 292 GLN D CB    1 
ATOM 3721 C CG    . GLN D 4 292 ? 134.125 146.646 169.994 1.00 323.41 ? 292 GLN D CG    1 
ATOM 3722 C CD    . GLN D 4 292 ? 134.839 147.029 168.713 1.00 323.02 ? 292 GLN D CD    1 
ATOM 3723 O OE1   . GLN D 4 292 ? 134.521 148.043 168.090 1.00 323.11 ? 292 GLN D OE1   1 
ATOM 3724 N NE2   . GLN D 4 292 ? 135.810 146.217 168.310 1.00 322.76 ? 292 GLN D NE2   1 
ATOM 3725 N N     . GLU D 4 293 ? 130.230 148.736 171.191 1.00 335.64 ? 293 GLU D N     1 
ATOM 3726 C CA    . GLU D 4 293 ? 129.369 149.728 171.819 1.00 335.73 ? 293 GLU D CA    1 
ATOM 3727 C C     . GLU D 4 293 ? 128.198 149.098 172.562 1.00 335.98 ? 293 GLU D C     1 
ATOM 3728 O O     . GLU D 4 293 ? 127.663 149.720 173.486 1.00 336.24 ? 293 GLU D O     1 
ATOM 3729 C CB    . GLU D 4 293 ? 128.868 150.730 170.775 1.00 335.48 ? 293 GLU D CB    1 
ATOM 3730 C CG    . GLU D 4 293 ? 128.237 150.118 169.534 1.00 335.51 ? 293 GLU D CG    1 
ATOM 3731 C CD    . GLU D 4 293 ? 126.746 149.897 169.682 1.00 335.58 ? 293 GLU D CD    1 
ATOM 3732 O OE1   . GLU D 4 293 ? 126.151 150.457 170.627 1.00 335.68 ? 293 GLU D OE1   1 
ATOM 3733 O OE2   . GLU D 4 293 ? 126.165 149.185 168.839 1.00 335.66 ? 293 GLU D OE2   1 
ATOM 3734 N N     . LEU D 4 294 ? 127.786 147.886 172.179 1.00 319.66 ? 294 LEU D N     1 
ATOM 3735 C CA    . LEU D 4 294 ? 126.816 147.151 172.984 1.00 318.48 ? 294 LEU D CA    1 
ATOM 3736 C C     . LEU D 4 294 ? 127.388 146.816 174.356 1.00 318.93 ? 294 LEU D C     1 
ATOM 3737 O O     . LEU D 4 294 ? 126.706 146.963 175.377 1.00 318.73 ? 294 LEU D O     1 
ATOM 3738 C CB    . LEU D 4 294 ? 126.390 145.874 172.259 1.00 316.93 ? 294 LEU D CB    1 
ATOM 3739 C CG    . LEU D 4 294 ? 125.412 146.005 171.092 1.00 316.34 ? 294 LEU D CG    1 
ATOM 3740 C CD1   . LEU D 4 294 ? 126.159 146.199 169.791 1.00 317.45 ? 294 LEU D CD1   1 
ATOM 3741 C CD2   . LEU D 4 294 ? 124.537 144.771 171.007 1.00 315.09 ? 294 LEU D CD2   1 
ATOM 3742 N N     . LYS D 4 295 ? 128.645 146.367 174.395 1.00 330.16 ? 295 LYS D N     1 
ATOM 3743 C CA    . LYS D 4 295 ? 129.296 146.054 175.664 1.00 329.76 ? 295 LYS D CA    1 
ATOM 3744 C C     . LYS D 4 295 ? 129.491 147.325 176.484 1.00 329.83 ? 295 LYS D C     1 
ATOM 3745 O O     . LYS D 4 295 ? 129.132 147.373 177.666 1.00 330.01 ? 295 LYS D O     1 
ATOM 3746 C CB    . LYS D 4 295 ? 130.635 145.356 175.382 1.00 329.03 ? 295 LYS D CB    1 
ATOM 3747 C CG    . LYS D 4 295 ? 131.688 145.226 176.510 1.00 328.58 ? 295 LYS D CG    1 
ATOM 3748 C CD    . LYS D 4 295 ? 131.142 145.062 177.932 1.00 328.75 ? 295 LYS D CD    1 
ATOM 3749 C CE    . LYS D 4 295 ? 132.254 145.218 178.959 1.00 328.45 ? 295 LYS D CE    1 
ATOM 3750 N NZ    . LYS D 4 295 ? 131.743 145.231 180.356 1.00 328.67 ? 295 LYS D NZ    1 
ATOM 3751 N N     . ALA D 4 296 ? 130.021 148.378 175.855 1.00 331.04 ? 296 ALA D N     1 
ATOM 3752 C CA    . ALA D 4 296 ? 130.287 149.621 176.573 1.00 330.43 ? 296 ALA D CA    1 
ATOM 3753 C C     . ALA D 4 296 ? 129.008 150.203 177.158 1.00 330.66 ? 296 ALA D C     1 
ATOM 3754 O O     . ALA D 4 296 ? 129.004 150.697 178.291 1.00 330.95 ? 296 ALA D O     1 
ATOM 3755 C CB    . ALA D 4 296 ? 130.959 150.631 175.644 1.00 330.05 ? 296 ALA D CB    1 
ATOM 3756 N N     . ALA D 4 297 ? 127.909 150.149 176.401 1.00 330.79 ? 297 ALA D N     1 
ATOM 3757 C CA    . ALA D 4 297 ? 126.628 150.605 176.931 1.00 330.48 ? 297 ALA D CA    1 
ATOM 3758 C C     . ALA D 4 297 ? 126.216 149.786 178.146 1.00 330.46 ? 297 ALA D C     1 
ATOM 3759 O O     . ALA D 4 297 ? 125.731 150.337 179.141 1.00 331.05 ? 297 ALA D O     1 
ATOM 3760 C CB    . ALA D 4 297 ? 125.555 150.532 175.847 1.00 330.25 ? 297 ALA D CB    1 
ATOM 3761 N N     . ALA D 4 298 ? 126.391 148.466 178.082 1.00 324.69 ? 298 ALA D N     1 
ATOM 3762 C CA    . ALA D 4 298 ? 126.155 147.638 179.259 1.00 324.02 ? 298 ALA D CA    1 
ATOM 3763 C C     . ALA D 4 298 ? 127.184 147.927 180.342 1.00 324.79 ? 298 ALA D C     1 
ATOM 3764 O O     . ALA D 4 298 ? 126.853 147.964 181.532 1.00 324.93 ? 298 ALA D O     1 
ATOM 3765 C CB    . ALA D 4 298 ? 126.174 146.160 178.874 1.00 323.56 ? 298 ALA D CB    1 
ATOM 3766 N N     . ASP D 4 299 ? 128.437 148.145 179.945 1.00 330.33 ? 299 ASP D N     1 
ATOM 3767 C CA    . ASP D 4 299 ? 129.491 148.415 180.916 1.00 330.01 ? 299 ASP D CA    1 
ATOM 3768 C C     . ASP D 4 299 ? 129.188 149.695 181.688 1.00 330.11 ? 299 ASP D C     1 
ATOM 3769 O O     . ASP D 4 299 ? 129.352 149.744 182.913 1.00 330.02 ? 299 ASP D O     1 
ATOM 3770 C CB    . ASP D 4 299 ? 130.838 148.487 180.177 1.00 329.88 ? 299 ASP D CB    1 
ATOM 3771 C CG    . ASP D 4 299 ? 131.915 149.316 180.893 1.00 329.79 ? 299 ASP D CG    1 
ATOM 3772 O OD1   . ASP D 4 299 ? 131.840 149.599 182.107 1.00 329.90 ? 299 ASP D OD1   1 
ATOM 3773 O OD2   . ASP D 4 299 ? 132.884 149.696 180.204 1.00 329.93 ? 299 ASP D OD2   1 
ATOM 3774 N N     . GLY D 4 300 ? 128.704 150.725 180.992 1.00 333.18 ? 300 GLY D N     1 
ATOM 3775 C CA    . GLY D 4 300 ? 128.496 152.014 181.634 1.00 333.22 ? 300 GLY D CA    1 
ATOM 3776 C C     . GLY D 4 300 ? 127.537 151.951 182.808 1.00 333.13 ? 300 GLY D C     1 
ATOM 3777 O O     . GLY D 4 300 ? 127.728 152.640 183.812 1.00 333.65 ? 300 GLY D O     1 
ATOM 3778 N N     . VAL D 4 301 ? 126.504 151.122 182.705 1.00 327.00 ? 301 VAL D N     1 
ATOM 3779 C CA    . VAL D 4 301 ? 125.489 151.018 183.745 1.00 326.43 ? 301 VAL D CA    1 
ATOM 3780 C C     . VAL D 4 301 ? 125.754 149.846 184.683 1.00 325.82 ? 301 VAL D C     1 
ATOM 3781 O O     . VAL D 4 301 ? 125.645 149.992 185.901 1.00 325.73 ? 301 VAL D O     1 
ATOM 3782 C CB    . VAL D 4 301 ? 124.083 150.922 183.115 1.00 326.15 ? 301 VAL D CB    1 
ATOM 3783 C CG1   . VAL D 4 301 ? 123.616 152.294 182.657 1.00 326.03 ? 301 VAL D CG1   1 
ATOM 3784 C CG2   . VAL D 4 301 ? 124.079 149.943 181.951 1.00 325.97 ? 301 VAL D CG2   1 
ATOM 3785 N N     . LEU D 4 302 ? 126.094 148.674 184.139 1.00 317.64 ? 302 LEU D N     1 
ATOM 3786 C CA    . LEU D 4 302 ? 126.275 147.496 184.983 1.00 317.20 ? 302 LEU D CA    1 
ATOM 3787 C C     . LEU D 4 302 ? 127.474 147.649 185.910 1.00 317.01 ? 302 LEU D C     1 
ATOM 3788 O O     . LEU D 4 302 ? 127.407 147.270 187.086 1.00 317.06 ? 302 LEU D O     1 
ATOM 3789 C CB    . LEU D 4 302 ? 126.423 146.244 184.118 1.00 317.15 ? 302 LEU D CB    1 
ATOM 3790 C CG    . LEU D 4 302 ? 125.205 145.845 183.282 1.00 316.73 ? 302 LEU D CG    1 
ATOM 3791 C CD1   . LEU D 4 302 ? 125.531 144.657 182.389 1.00 316.50 ? 302 LEU D CD1   1 
ATOM 3792 C CD2   . LEU D 4 302 ? 124.012 145.539 184.175 1.00 316.54 ? 302 LEU D CD2   1 
ATOM 3793 N N     . SER D 4 303 ? 128.581 148.193 185.401 1.00 316.10 ? 303 SER D N     1 
ATOM 3794 C CA    . SER D 4 303 ? 129.773 148.348 186.229 1.00 316.00 ? 303 SER D CA    1 
ATOM 3795 C C     . SER D 4 303 ? 129.537 149.342 187.359 1.00 316.26 ? 303 SER D C     1 
ATOM 3796 O O     . SER D 4 303 ? 130.030 149.149 188.476 1.00 316.40 ? 303 SER D O     1 
ATOM 3797 C CB    . SER D 4 303 ? 130.960 148.781 185.370 1.00 315.87 ? 303 SER D CB    1 
ATOM 3798 O OG    . SER D 4 303 ? 130.714 150.037 184.763 1.00 316.65 ? 303 SER D OG    1 
ATOM 3799 N N     . GLU D 4 304 ? 128.796 150.419 187.086 1.00 312.53 ? 304 GLU D N     1 
ATOM 3800 C CA    . GLU D 4 304 ? 128.509 151.399 188.130 1.00 312.22 ? 304 GLU D CA    1 
ATOM 3801 C C     . GLU D 4 304 ? 127.683 150.782 189.251 1.00 311.52 ? 304 GLU D C     1 
ATOM 3802 O O     . GLU D 4 304 ? 127.936 151.040 190.434 1.00 311.39 ? 304 GLU D O     1 
ATOM 3803 C CB    . GLU D 4 304 ? 127.789 152.609 187.531 1.00 312.12 ? 304 GLU D CB    1 
ATOM 3804 C CG    . GLU D 4 304 ? 127.198 153.568 188.558 1.00 311.49 ? 304 GLU D CG    1 
ATOM 3805 C CD    . GLU D 4 304 ? 125.766 153.228 188.927 1.00 311.11 ? 304 GLU D CD    1 
ATOM 3806 O OE1   . GLU D 4 304 ? 125.086 152.560 188.121 1.00 311.32 ? 304 GLU D OE1   1 
ATOM 3807 O OE2   . GLU D 4 304 ? 125.325 153.623 190.027 1.00 310.70 ? 304 GLU D OE2   1 
ATOM 3808 N N     . VAL D 4 305 ? 126.686 149.969 188.898 1.00 303.40 ? 305 VAL D N     1 
ATOM 3809 C CA    . VAL D 4 305 ? 125.864 149.313 189.910 1.00 302.76 ? 305 VAL D CA    1 
ATOM 3810 C C     . VAL D 4 305 ? 126.708 148.351 190.736 1.00 303.09 ? 305 VAL D C     1 
ATOM 3811 O O     . VAL D 4 305 ? 126.567 148.272 191.963 1.00 302.95 ? 305 VAL D O     1 
ATOM 3812 C CB    . VAL D 4 305 ? 124.669 148.606 189.243 1.00 302.84 ? 305 VAL D CB    1 
ATOM 3813 C CG1   . VAL D 4 305 ? 124.092 147.540 190.157 1.00 303.10 ? 305 VAL D CG1   1 
ATOM 3814 C CG2   . VAL D 4 305 ? 123.605 149.621 188.873 1.00 302.76 ? 305 VAL D CG2   1 
ATOM 3815 N N     . ARG D 4 306 ? 127.602 147.610 190.077 1.00 301.65 ? 306 ARG D N     1 
ATOM 3816 C CA    . ARG D 4 306 ? 128.492 146.706 190.798 1.00 301.54 ? 306 ARG D CA    1 
ATOM 3817 C C     . ARG D 4 306 ? 129.384 147.489 191.756 1.00 301.72 ? 306 ARG D C     1 
ATOM 3818 O O     . ARG D 4 306 ? 129.582 147.077 192.906 1.00 301.56 ? 306 ARG D O     1 
ATOM 3819 C CB    . ARG D 4 306 ? 129.317 145.896 189.787 1.00 301.14 ? 306 ARG D CB    1 
ATOM 3820 C CG    . ARG D 4 306 ? 130.536 145.091 190.290 1.00 300.70 ? 306 ARG D CG    1 
ATOM 3821 C CD    . ARG D 4 306 ? 130.383 144.487 191.684 1.00 300.81 ? 306 ARG D CD    1 
ATOM 3822 N NE    . ARG D 4 306 ? 129.446 143.372 191.722 1.00 300.57 ? 306 ARG D NE    1 
ATOM 3823 C CZ    . ARG D 4 306 ? 129.277 142.575 192.769 1.00 300.61 ? 306 ARG D CZ    1 
ATOM 3824 N NH1   . ARG D 4 306 ? 129.968 142.745 193.885 1.00 300.76 ? 306 ARG D NH1   1 
ATOM 3825 N NH2   . ARG D 4 306 ? 128.392 141.586 192.697 1.00 300.79 ? 306 ARG D NH2   1 
ATOM 3826 N N     . LYS D 4 307 ? 129.900 148.639 191.311 1.00 306.09 ? 307 LYS D N     1 
ATOM 3827 C CA    . LYS D 4 307 ? 130.752 149.463 192.165 1.00 305.86 ? 307 LYS D CA    1 
ATOM 3828 C C     . LYS D 4 307 ? 130.080 149.743 193.503 1.00 305.29 ? 307 LYS D C     1 
ATOM 3829 O O     . LYS D 4 307 ? 130.705 149.631 194.563 1.00 305.70 ? 307 LYS D O     1 
ATOM 3830 C CB    . LYS D 4 307 ? 131.095 150.774 191.457 1.00 305.69 ? 307 LYS D CB    1 
ATOM 3831 C CG    . LYS D 4 307 ? 132.276 150.689 190.505 1.00 305.33 ? 307 LYS D CG    1 
ATOM 3832 C CD    . LYS D 4 307 ? 132.082 151.610 189.309 1.00 305.34 ? 307 LYS D CD    1 
ATOM 3833 C CE    . LYS D 4 307 ? 133.043 151.270 188.183 1.00 305.15 ? 307 LYS D CE    1 
ATOM 3834 N NZ    . LYS D 4 307 ? 132.482 151.623 186.850 1.00 305.64 ? 307 LYS D NZ    1 
ATOM 3835 N N     . LYS D 4 308 ? 128.797 150.102 193.470 1.00 287.46 ? 308 LYS D N     1 
ATOM 3836 C CA    . LYS D 4 308 ? 128.052 150.253 194.713 1.00 286.55 ? 308 LYS D CA    1 
ATOM 3837 C C     . LYS D 4 308 ? 127.746 148.900 195.340 1.00 286.31 ? 308 LYS D C     1 
ATOM 3838 O O     . LYS D 4 308 ? 127.786 148.758 196.567 1.00 286.17 ? 308 LYS D O     1 
ATOM 3839 C CB    . LYS D 4 308 ? 126.766 151.040 194.468 1.00 286.05 ? 308 LYS D CB    1 
ATOM 3840 C CG    . LYS D 4 308 ? 126.951 152.549 194.473 1.00 285.89 ? 308 LYS D CG    1 
ATOM 3841 C CD    . LYS D 4 308 ? 127.399 153.065 195.839 1.00 285.43 ? 308 LYS D CD    1 
ATOM 3842 C CE    . LYS D 4 308 ? 126.527 152.531 196.968 1.00 284.57 ? 308 LYS D CE    1 
ATOM 3843 N NZ    . LYS D 4 308 ? 127.095 152.836 198.308 1.00 284.19 ? 308 LYS D NZ    1 
ATOM 3844 N N     . GLN D 4 309 ? 127.433 147.894 194.518 1.00 290.45 ? 309 GLN D N     1 
ATOM 3845 C CA    . GLN D 4 309 ? 127.165 146.565 195.060 1.00 290.48 ? 309 GLN D CA    1 
ATOM 3846 C C     . GLN D 4 309 ? 128.410 145.966 195.699 1.00 290.89 ? 309 GLN D C     1 
ATOM 3847 O O     . GLN D 4 309 ? 128.331 145.347 196.766 1.00 291.14 ? 309 GLN D O     1 
ATOM 3848 C CB    . GLN D 4 309 ? 126.620 145.645 193.969 1.00 290.39 ? 309 GLN D CB    1 
ATOM 3849 C CG    . GLN D 4 309 ? 125.113 145.481 194.021 1.00 290.02 ? 309 GLN D CG    1 
ATOM 3850 C CD    . GLN D 4 309 ? 124.535 145.012 192.707 1.00 290.54 ? 309 GLN D CD    1 
ATOM 3851 O OE1   . GLN D 4 309 ? 125.230 144.966 191.694 1.00 291.30 ? 309 GLN D OE1   1 
ATOM 3852 N NE2   . GLN D 4 309 ? 123.254 144.663 192.715 1.00 290.68 ? 309 GLN D NE2   1 
ATOM 3853 N N     . ALA D 4 310 ? 129.570 146.134 195.060 1.00 284.36 ? 310 ALA D N     1 
ATOM 3854 C CA    . ALA D 4 310 ? 130.817 145.731 195.700 1.00 283.65 ? 310 ALA D CA    1 
ATOM 3855 C C     . ALA D 4 310 ? 131.037 146.516 196.985 1.00 283.24 ? 310 ALA D C     1 
ATOM 3856 O O     . ALA D 4 310 ? 131.468 145.956 198.000 1.00 282.74 ? 310 ALA D O     1 
ATOM 3857 C CB    . ALA D 4 310 ? 131.993 145.921 194.742 1.00 283.36 ? 310 ALA D CB    1 
ATOM 3858 N N     . ASP D 4 311 ? 130.740 147.817 196.960 1.00 274.90 ? 311 ASP D N     1 
ATOM 3859 C CA    . ASP D 4 311 ? 130.733 148.595 198.192 1.00 274.30 ? 311 ASP D CA    1 
ATOM 3860 C C     . ASP D 4 311 ? 129.674 148.069 199.151 1.00 274.00 ? 311 ASP D C     1 
ATOM 3861 O O     . ASP D 4 311 ? 129.925 147.941 200.353 1.00 274.22 ? 311 ASP D O     1 
ATOM 3862 C CB    . ASP D 4 311 ? 130.494 150.072 197.874 1.00 274.46 ? 311 ASP D CB    1 
ATOM 3863 C CG    . ASP D 4 311 ? 129.924 150.851 199.052 1.00 274.04 ? 311 ASP D CG    1 
ATOM 3864 O OD1   . ASP D 4 311 ? 130.349 150.619 200.205 1.00 274.03 ? 311 ASP D OD1   1 
ATOM 3865 O OD2   . ASP D 4 311 ? 129.035 151.696 198.824 1.00 273.69 ? 311 ASP D OD2   1 
ATOM 3866 N N     . THR D 4 312 ? 128.484 147.750 198.636 1.00 271.60 ? 312 THR D N     1 
ATOM 3867 C CA    . THR D 4 312 ? 127.443 147.189 199.490 1.00 271.55 ? 312 THR D CA    1 
ATOM 3868 C C     . THR D 4 312 ? 127.894 145.871 200.107 1.00 270.99 ? 312 THR D C     1 
ATOM 3869 O O     . THR D 4 312 ? 127.604 145.592 201.275 1.00 271.13 ? 312 THR D O     1 
ATOM 3870 C CB    . THR D 4 312 ? 126.148 147.001 198.697 1.00 271.87 ? 312 THR D CB    1 
ATOM 3871 O OG1   . THR D 4 312 ? 126.018 148.050 197.731 1.00 271.50 ? 312 THR D OG1   1 
ATOM 3872 C CG2   . THR D 4 312 ? 124.949 147.032 199.626 1.00 271.47 ? 312 THR D CG2   1 
ATOM 3873 N N     . LYS D 4 313 ? 128.608 145.049 199.338 1.00 253.91 ? 313 LYS D N     1 
ATOM 3874 C CA    . LYS D 4 313 ? 129.158 143.818 199.891 1.00 252.78 ? 313 LYS D CA    1 
ATOM 3875 C C     . LYS D 4 313 ? 130.318 144.105 200.839 1.00 252.28 ? 313 LYS D C     1 
ATOM 3876 O O     . LYS D 4 313 ? 130.618 143.287 201.717 1.00 252.19 ? 313 LYS D O     1 
ATOM 3877 C CB    . LYS D 4 313 ? 129.602 142.893 198.756 1.00 252.77 ? 313 LYS D CB    1 
ATOM 3878 C CG    . LYS D 4 313 ? 130.097 141.528 199.198 1.00 252.15 ? 313 LYS D CG    1 
ATOM 3879 C CD    . LYS D 4 313 ? 129.656 140.446 198.224 1.00 252.65 ? 313 LYS D CD    1 
ATOM 3880 C CE    . LYS D 4 313 ? 128.141 140.397 198.101 1.00 252.73 ? 313 LYS D CE    1 
ATOM 3881 N NZ    . LYS D 4 313 ? 127.703 139.464 197.029 1.00 252.82 ? 313 LYS D NZ    1 
ATOM 3882 N N     . ARG D 4 314 ? 130.964 145.265 200.689 1.00 250.42 ? 314 ARG D N     1 
ATOM 3883 C CA    . ARG D 4 314 ? 132.182 145.551 201.441 1.00 251.11 ? 314 ARG D CA    1 
ATOM 3884 C C     . ARG D 4 314 ? 131.917 145.639 202.940 1.00 250.42 ? 314 ARG D C     1 
ATOM 3885 O O     . ARG D 4 314 ? 132.825 145.402 203.744 1.00 250.07 ? 314 ARG D O     1 
ATOM 3886 C CB    . ARG D 4 314 ? 132.810 146.849 200.921 1.00 251.80 ? 314 ARG D CB    1 
ATOM 3887 C CG    . ARG D 4 314 ? 134.172 147.301 201.501 1.00 250.27 ? 314 ARG D CG    1 
ATOM 3888 C CD    . ARG D 4 314 ? 135.162 146.209 201.972 1.00 249.97 ? 314 ARG D CD    1 
ATOM 3889 N NE    . ARG D 4 314 ? 135.110 144.937 201.255 1.00 251.00 ? 314 ARG D NE    1 
ATOM 3890 C CZ    . ARG D 4 314 ? 135.340 144.786 199.957 1.00 250.40 ? 314 ARG D CZ    1 
ATOM 3891 N NH1   . ARG D 4 314 ? 135.681 145.808 199.188 1.00 250.30 ? 314 ARG D NH1   1 
ATOM 3892 N NH2   . ARG D 4 314 ? 135.235 143.575 199.417 1.00 250.12 ? 314 ARG D NH2   1 
ATOM 3893 N N     . MET D 4 315 ? 130.693 145.983 203.344 1.00 242.23 ? 315 MET D N     1 
ATOM 3894 C CA    . MET D 4 315 ? 130.389 145.998 204.772 1.00 241.03 ? 315 MET D CA    1 
ATOM 3895 C C     . MET D 4 315 ? 130.099 144.603 205.306 1.00 240.61 ? 315 MET D C     1 
ATOM 3896 O O     . MET D 4 315 ? 130.159 144.384 206.521 1.00 240.55 ? 315 MET D O     1 
ATOM 3897 C CB    . MET D 4 315 ? 129.212 146.924 205.064 1.00 241.18 ? 315 MET D CB    1 
ATOM 3898 C CG    . MET D 4 315 ? 129.526 148.386 204.855 1.00 240.78 ? 315 MET D CG    1 
ATOM 3899 S SD    . MET D 4 315 ? 129.313 148.942 203.159 1.00 242.56 ? 315 MET D SD    1 
ATOM 3900 C CE    . MET D 4 315 ? 127.592 148.528 202.886 1.00 241.43 ? 315 MET D CE    1 
ATOM 3901 N N     . VAL D 4 316 ? 129.779 143.653 204.426 1.00 232.68 ? 316 VAL D N     1 
ATOM 3902 C CA    . VAL D 4 316 ? 129.443 142.308 204.882 1.00 232.52 ? 316 VAL D CA    1 
ATOM 3903 C C     . VAL D 4 316 ? 130.689 141.591 205.386 1.00 233.14 ? 316 VAL D C     1 
ATOM 3904 O O     . VAL D 4 316 ? 130.722 141.087 206.514 1.00 233.40 ? 316 VAL D O     1 
ATOM 3905 C CB    . VAL D 4 316 ? 128.752 141.517 203.757 1.00 232.12 ? 316 VAL D CB    1 
ATOM 3906 C CG1   . VAL D 4 316 ? 128.475 140.091 204.207 1.00 231.36 ? 316 VAL D CG1   1 
ATOM 3907 C CG2   . VAL D 4 316 ? 127.465 142.207 203.335 1.00 232.53 ? 316 VAL D CG2   1 
ATOM 3908 N N     . ASP D 4 317 ? 131.735 141.542 204.559 1.00 231.69 ? 317 ASP D N     1 
ATOM 3909 C CA    . ASP D 4 317 ? 132.984 140.917 204.976 1.00 231.01 ? 317 ASP D CA    1 
ATOM 3910 C C     . ASP D 4 317 ? 133.698 141.713 206.060 1.00 230.93 ? 317 ASP D C     1 
ATOM 3911 O O     . ASP D 4 317 ? 134.510 141.141 206.794 1.00 230.77 ? 317 ASP D O     1 
ATOM 3912 C CB    . ASP D 4 317 ? 133.898 140.719 203.768 1.00 231.25 ? 317 ASP D CB    1 
ATOM 3913 C CG    . ASP D 4 317 ? 133.907 141.918 202.851 1.00 232.35 ? 317 ASP D CG    1 
ATOM 3914 O OD1   . ASP D 4 317 ? 133.171 142.879 203.141 1.00 232.59 ? 317 ASP D OD1   1 
ATOM 3915 O OD2   . ASP D 4 317 ? 134.638 141.900 201.839 1.00 233.10 ? 317 ASP D OD2   1 
ATOM 3916 N N     . ILE D 4 318 ? 133.420 143.013 206.179 1.00 224.35 ? 318 ILE D N     1 
ATOM 3917 C CA    . ILE D 4 318 ? 133.921 143.767 207.325 1.00 223.97 ? 318 ILE D CA    1 
ATOM 3918 C C     . ILE D 4 318 ? 133.354 143.190 208.613 1.00 224.07 ? 318 ILE D C     1 
ATOM 3919 O O     . ILE D 4 318 ? 134.085 142.936 209.577 1.00 223.91 ? 318 ILE D O     1 
ATOM 3920 C CB    . ILE D 4 318 ? 133.585 145.263 207.182 1.00 223.51 ? 318 ILE D CB    1 
ATOM 3921 C CG1   . ILE D 4 318 ? 134.633 145.974 206.329 1.00 222.95 ? 318 ILE D CG1   1 
ATOM 3922 C CG2   . ILE D 4 318 ? 133.479 145.931 208.548 1.00 222.72 ? 318 ILE D CG2   1 
ATOM 3923 C CD1   . ILE D 4 318 ? 134.235 147.379 205.938 1.00 224.51 ? 318 ILE D CD1   1 
ATOM 3924 N N     . LEU D 4 319 ? 132.041 142.950 208.639 1.00 217.58 ? 319 LEU D N     1 
ATOM 3925 C CA    . LEU D 4 319 ? 131.432 142.362 209.825 1.00 215.56 ? 319 LEU D CA    1 
ATOM 3926 C C     . LEU D 4 319 ? 131.765 140.884 209.948 1.00 215.39 ? 319 LEU D C     1 
ATOM 3927 O O     . LEU D 4 319 ? 131.783 140.349 211.059 1.00 214.15 ? 319 LEU D O     1 
ATOM 3928 C CB    . LEU D 4 319 ? 129.921 142.571 209.803 1.00 215.42 ? 319 LEU D CB    1 
ATOM 3929 C CG    . LEU D 4 319 ? 129.446 143.784 210.602 1.00 215.60 ? 319 LEU D CG    1 
ATOM 3930 C CD1   . LEU D 4 319 ? 129.995 143.720 212.019 1.00 215.88 ? 319 LEU D CD1   1 
ATOM 3931 C CD2   . LEU D 4 319 ? 129.849 145.080 209.920 1.00 215.89 ? 319 LEU D CD2   1 
ATOM 3932 N N     . ARG D 4 320 ? 132.030 140.213 208.828 1.00 211.38 ? 320 ARG D N     1 
ATOM 3933 C CA    . ARG D 4 320 ? 132.475 138.824 208.882 1.00 211.67 ? 320 ARG D CA    1 
ATOM 3934 C C     . ARG D 4 320 ? 133.858 138.718 209.517 1.00 212.80 ? 320 ARG D C     1 
ATOM 3935 O O     . ARG D 4 320 ? 134.068 137.949 210.465 1.00 214.21 ? 320 ARG D O     1 
ATOM 3936 C CB    . ARG D 4 320 ? 132.461 138.239 207.467 1.00 211.43 ? 320 ARG D CB    1 
ATOM 3937 C CG    . ARG D 4 320 ? 133.156 136.900 207.275 1.00 210.93 ? 320 ARG D CG    1 
ATOM 3938 C CD    . ARG D 4 320 ? 132.693 135.844 208.258 1.00 211.11 ? 320 ARG D CD    1 
ATOM 3939 N NE    . ARG D 4 320 ? 133.512 134.644 208.152 1.00 211.18 ? 320 ARG D NE    1 
ATOM 3940 C CZ    . ARG D 4 320 ? 134.720 134.514 208.683 1.00 210.92 ? 320 ARG D CZ    1 
ATOM 3941 N NH1   . ARG D 4 320 ? 135.290 135.503 209.350 1.00 210.51 ? 320 ARG D NH1   1 
ATOM 3942 N NH2   . ARG D 4 320 ? 135.376 133.368 208.532 1.00 210.41 ? 320 ARG D NH2   1 
ATOM 3943 N N     . ALA D 4 321 ? 134.812 139.509 209.021 1.00 210.23 ? 321 ALA D N     1 
ATOM 3944 C CA    . ALA D 4 321 ? 136.157 139.490 209.583 1.00 208.88 ? 321 ALA D CA    1 
ATOM 3945 C C     . ALA D 4 321 ? 136.169 140.013 211.012 1.00 210.07 ? 321 ALA D C     1 
ATOM 3946 O O     . ALA D 4 321 ? 136.878 139.475 211.869 1.00 210.86 ? 321 ALA D O     1 
ATOM 3947 C CB    . ALA D 4 321 ? 137.106 140.301 208.704 1.00 208.09 ? 321 ALA D CB    1 
ATOM 3948 N N     . LEU D 4 322 ? 135.398 141.069 211.286 1.00 214.37 ? 322 LEU D N     1 
ATOM 3949 C CA    . LEU D 4 322 ? 135.318 141.594 212.646 1.00 214.23 ? 322 LEU D CA    1 
ATOM 3950 C C     . LEU D 4 322 ? 134.714 140.570 213.597 1.00 214.47 ? 322 LEU D C     1 
ATOM 3951 O O     . LEU D 4 322 ? 135.180 140.410 214.731 1.00 214.56 ? 322 LEU D O     1 
ATOM 3952 C CB    . LEU D 4 322 ? 134.495 142.880 212.663 1.00 213.70 ? 322 LEU D CB    1 
ATOM 3953 C CG    . LEU D 4 322 ? 134.685 143.786 213.876 1.00 213.07 ? 322 LEU D CG    1 
ATOM 3954 C CD1   . LEU D 4 322 ? 134.917 145.227 213.454 1.00 212.41 ? 322 LEU D CD1   1 
ATOM 3955 C CD2   . LEU D 4 322 ? 133.486 143.667 214.790 1.00 214.03 ? 322 LEU D CD2   1 
ATOM 3956 N N     . GLU D 4 323 ? 133.668 139.873 213.151 1.00 221.92 ? 323 GLU D N     1 
ATOM 3957 C CA    . GLU D 4 323 ? 133.050 138.843 213.974 1.00 222.25 ? 323 GLU D CA    1 
ATOM 3958 C C     . GLU D 4 323 ? 134.031 137.720 214.268 1.00 222.14 ? 323 GLU D C     1 
ATOM 3959 O O     . GLU D 4 323 ? 134.091 137.218 215.396 1.00 221.02 ? 323 GLU D O     1 
ATOM 3960 C CB    . GLU D 4 323 ? 131.804 138.303 213.275 1.00 222.77 ? 323 GLU D CB    1 
ATOM 3961 C CG    . GLU D 4 323 ? 130.655 137.984 214.205 1.00 223.24 ? 323 GLU D CG    1 
ATOM 3962 C CD    . GLU D 4 323 ? 129.310 138.164 213.537 1.00 223.05 ? 323 GLU D CD    1 
ATOM 3963 O OE1   . GLU D 4 323 ? 129.266 138.770 212.446 1.00 223.15 ? 323 GLU D OE1   1 
ATOM 3964 O OE2   . GLU D 4 323 ? 128.299 137.695 214.097 1.00 222.12 ? 323 GLU D OE2   1 
ATOM 3965 N N     . LYS D 4 324 ? 134.809 137.312 213.263 1.00 209.90 ? 324 LYS D N     1 
ATOM 3966 C CA    . LYS D 4 324 ? 135.850 136.319 213.508 1.00 208.24 ? 324 LYS D CA    1 
ATOM 3967 C C     . LYS D 4 324 ? 136.850 136.826 214.539 1.00 207.70 ? 324 LYS D C     1 
ATOM 3968 O O     . LYS D 4 324 ? 137.120 136.152 215.538 1.00 207.58 ? 324 LYS D O     1 
ATOM 3969 C CB    . LYS D 4 324 ? 136.556 135.958 212.203 1.00 207.86 ? 324 LYS D CB    1 
ATOM 3970 C CG    . LYS D 4 324 ? 137.196 134.581 212.206 1.00 207.10 ? 324 LYS D CG    1 
ATOM 3971 C CD    . LYS D 4 324 ? 136.265 133.527 212.787 1.00 207.31 ? 324 LYS D CD    1 
ATOM 3972 C CE    . LYS D 4 324 ? 135.138 133.188 211.826 1.00 206.39 ? 324 LYS D CE    1 
ATOM 3973 N NZ    . LYS D 4 324 ? 134.468 131.907 212.178 1.00 206.15 ? 324 LYS D NZ    1 
ATOM 3974 N N     . LEU D 4 325 ? 137.375 138.038 214.330 1.00 206.73 ? 325 LEU D N     1 
ATOM 3975 C CA    . LEU D 4 325 ? 138.357 138.609 215.250 1.00 206.52 ? 325 LEU D CA    1 
ATOM 3976 C C     . LEU D 4 325 ? 137.820 138.657 216.670 1.00 207.05 ? 325 LEU D C     1 
ATOM 3977 O O     . LEU D 4 325 ? 138.574 138.488 217.635 1.00 206.31 ? 325 LEU D O     1 
ATOM 3978 C CB    . LEU D 4 325 ? 138.757 140.010 214.785 1.00 206.32 ? 325 LEU D CB    1 
ATOM 3979 C CG    . LEU D 4 325 ? 140.116 140.555 215.231 1.00 204.81 ? 325 LEU D CG    1 
ATOM 3980 C CD1   . LEU D 4 325 ? 140.645 141.542 214.207 1.00 204.52 ? 325 LEU D CD1   1 
ATOM 3981 C CD2   . LEU D 4 325 ? 140.028 141.214 216.599 1.00 204.69 ? 325 LEU D CD2   1 
ATOM 3982 N N     . ARG D 4 326 ? 136.516 138.893 216.818 1.00 223.15 ? 326 ARG D N     1 
ATOM 3983 C CA    . ARG D 4 326 ? 135.924 138.878 218.147 1.00 222.51 ? 326 ARG D CA    1 
ATOM 3984 C C     . ARG D 4 326 ? 136.043 137.496 218.775 1.00 223.79 ? 326 ARG D C     1 
ATOM 3985 O O     . ARG D 4 326 ? 136.257 137.373 219.986 1.00 223.18 ? 326 ARG D O     1 
ATOM 3986 C CB    . ARG D 4 326 ? 134.461 139.313 218.078 1.00 221.44 ? 326 ARG D CB    1 
ATOM 3987 C CG    . ARG D 4 326 ? 133.982 139.999 219.338 1.00 221.19 ? 326 ARG D CG    1 
ATOM 3988 C CD    . ARG D 4 326 ? 132.507 140.287 219.301 1.00 221.98 ? 326 ARG D CD    1 
ATOM 3989 N NE    . ARG D 4 326 ? 131.728 139.066 219.462 1.00 222.84 ? 326 ARG D NE    1 
ATOM 3990 C CZ    . ARG D 4 326 ? 131.479 138.493 220.632 1.00 223.99 ? 326 ARG D CZ    1 
ATOM 3991 N NH1   . ARG D 4 326 ? 131.936 139.005 221.762 1.00 224.41 ? 326 ARG D NH1   1 
ATOM 3992 N NH2   . ARG D 4 326 ? 130.757 137.377 220.667 1.00 223.51 ? 326 ARG D NH2   1 
ATOM 3993 N N     . LYS D 4 327 ? 135.917 136.442 217.962 1.00 226.41 ? 327 LYS D N     1 
ATOM 3994 C CA    . LYS D 4 327 ? 135.915 135.082 218.493 1.00 226.94 ? 327 LYS D CA    1 
ATOM 3995 C C     . LYS D 4 327 ? 137.271 134.700 219.075 1.00 226.68 ? 327 LYS D C     1 
ATOM 3996 O O     . LYS D 4 327 ? 137.353 134.235 220.218 1.00 226.82 ? 327 LYS D O     1 
ATOM 3997 C CB    . LYS D 4 327 ? 135.506 134.091 217.402 1.00 226.32 ? 327 LYS D CB    1 
ATOM 3998 C CG    . LYS D 4 327 ? 135.779 132.637 217.760 1.00 225.40 ? 327 LYS D CG    1 
ATOM 3999 C CD    . LYS D 4 327 ? 135.232 131.685 216.708 1.00 224.69 ? 327 LYS D CD    1 
ATOM 4000 C CE    . LYS D 4 327 ? 136.348 131.137 215.829 1.00 224.60 ? 327 LYS D CE    1 
ATOM 4001 N NZ    . LYS D 4 327 ? 135.842 130.628 214.524 1.00 223.45 ? 327 LYS D NZ    1 
ATOM 4002 N N     . LEU D 4 328 ? 138.353 134.888 218.309 1.00 210.50 ? 328 LEU D N     1 
ATOM 4003 C CA    . LEU D 4 328 ? 139.653 134.431 218.791 1.00 208.96 ? 328 LEU D CA    1 
ATOM 4004 C C     . LEU D 4 328 ? 140.139 135.227 219.993 1.00 208.70 ? 328 LEU D C     1 
ATOM 4005 O O     . LEU D 4 328 ? 140.957 134.716 220.765 1.00 209.99 ? 328 LEU D O     1 
ATOM 4006 C CB    . LEU D 4 328 ? 140.719 134.482 217.692 1.00 207.75 ? 328 LEU D CB    1 
ATOM 4007 C CG    . LEU D 4 328 ? 140.419 134.071 216.251 1.00 207.51 ? 328 LEU D CG    1 
ATOM 4008 C CD1   . LEU D 4 328 ? 139.964 135.252 215.430 1.00 207.29 ? 328 LEU D CD1   1 
ATOM 4009 C CD2   . LEU D 4 328 ? 141.638 133.423 215.624 1.00 207.23 ? 328 LEU D CD2   1 
ATOM 4010 N N     . ARG D 4 329 ? 139.660 136.456 220.174 1.00 214.78 ? 329 ARG D N     1 
ATOM 4011 C CA    . ARG D 4 329 ? 140.042 137.221 221.351 1.00 216.36 ? 329 ARG D CA    1 
ATOM 4012 C C     . ARG D 4 329 ? 139.280 136.781 222.593 1.00 218.59 ? 329 ARG D C     1 
ATOM 4013 O O     . ARG D 4 329 ? 139.711 137.089 223.709 1.00 219.44 ? 329 ARG D O     1 
ATOM 4014 C CB    . ARG D 4 329 ? 139.840 138.716 221.093 1.00 216.05 ? 329 ARG D CB    1 
ATOM 4015 C CG    . ARG D 4 329 ? 141.147 139.502 221.037 1.00 216.79 ? 329 ARG D CG    1 
ATOM 4016 C CD    . ARG D 4 329 ? 140.926 141.003 221.151 1.00 216.82 ? 329 ARG D CD    1 
ATOM 4017 N NE    . ARG D 4 329 ? 141.934 141.751 220.408 1.00 214.91 ? 329 ARG D NE    1 
ATOM 4018 C CZ    . ARG D 4 329 ? 141.722 142.921 219.821 1.00 214.97 ? 329 ARG D CZ    1 
ATOM 4019 N NH1   . ARG D 4 329 ? 140.540 143.509 219.859 1.00 216.19 ? 329 ARG D NH1   1 
ATOM 4020 N NH2   . ARG D 4 329 ? 142.722 143.515 219.177 1.00 213.75 ? 329 ARG D NH2   1 
ATOM 4021 N N     . LYS D 4 330 ? 138.166 136.063 222.425 1.00 233.64 ? 330 LYS D N     1 
ATOM 4022 C CA    . LYS D 4 330 ? 137.488 135.458 223.571 1.00 233.43 ? 330 LYS D CA    1 
ATOM 4023 C C     . LYS D 4 330 ? 138.206 134.206 224.054 1.00 233.55 ? 330 LYS D C     1 
ATOM 4024 O O     . LYS D 4 330 ? 138.128 133.870 225.241 1.00 232.80 ? 330 LYS D O     1 
ATOM 4025 C CB    . LYS D 4 330 ? 136.026 135.158 223.226 1.00 233.23 ? 330 LYS D CB    1 
ATOM 4026 C CG    . LYS D 4 330 ? 135.228 136.375 222.754 1.00 233.39 ? 330 LYS D CG    1 
ATOM 4027 C CD    . LYS D 4 330 ? 135.781 137.663 223.361 1.00 232.98 ? 330 LYS D CD    1 
ATOM 4028 C CE    . LYS D 4 330 ? 135.170 138.898 222.749 1.00 231.99 ? 330 LYS D CE    1 
ATOM 4029 N NZ    . LYS D 4 330 ? 135.960 139.269 221.548 1.00 230.20 ? 330 LYS D NZ    1 
ATOM 4030 N N     . GLU D 4 331 ? 138.907 133.507 223.159 1.00 242.03 ? 331 GLU D N     1 
ATOM 4031 C CA    . GLU D 4 331 ? 139.772 132.419 223.600 1.00 241.87 ? 331 GLU D CA    1 
ATOM 4032 C C     . GLU D 4 331 ? 140.884 132.946 224.495 1.00 242.16 ? 331 GLU D C     1 
ATOM 4033 O O     . GLU D 4 331 ? 141.245 132.311 225.493 1.00 242.60 ? 331 GLU D O     1 
ATOM 4034 C CB    . GLU D 4 331 ? 140.350 131.685 222.391 1.00 241.88 ? 331 GLU D CB    1 
ATOM 4035 C CG    . GLU D 4 331 ? 139.444 131.694 221.170 1.00 241.94 ? 331 GLU D CG    1 
ATOM 4036 C CD    . GLU D 4 331 ? 138.110 131.016 221.421 1.00 241.34 ? 331 GLU D CD    1 
ATOM 4037 O OE1   . GLU D 4 331 ? 138.061 130.087 222.254 1.00 241.53 ? 331 GLU D OE1   1 
ATOM 4038 O OE2   . GLU D 4 331 ? 137.110 131.411 220.785 1.00 240.65 ? 331 GLU D OE2   1 
ATOM 4039 N N     . ALA D 4 332 ? 141.442 134.107 224.149 1.00 251.69 ? 332 ALA D N     1 
ATOM 4040 C CA    . ALA D 4 332 ? 142.383 134.767 225.043 1.00 251.44 ? 332 ALA D CA    1 
ATOM 4041 C C     . ALA D 4 332 ? 141.668 135.461 226.195 1.00 252.28 ? 332 ALA D C     1 
ATOM 4042 O O     . ALA D 4 332 ? 142.314 135.870 227.167 1.00 252.51 ? 332 ALA D O     1 
ATOM 4043 C CB    . ALA D 4 332 ? 143.237 135.766 224.264 1.00 251.21 ? 332 ALA D CB    1 
ATOM 4044 N N     . ALA D 4 333 ? 140.344 135.603 226.110 1.00 262.23 ? 333 ALA D N     1 
ATOM 4045 C CA    . ALA D 4 333 ? 139.576 136.243 227.171 1.00 262.27 ? 333 ALA D CA    1 
ATOM 4046 C C     . ALA D 4 333 ? 139.157 135.277 228.269 1.00 262.96 ? 333 ALA D C     1 
ATOM 4047 O O     . ALA D 4 333 ? 138.374 135.666 229.142 1.00 263.21 ? 333 ALA D O     1 
ATOM 4048 C CB    . ALA D 4 333 ? 138.334 136.932 226.601 1.00 261.40 ? 333 ALA D CB    1 
ATOM 4049 N N     . ALA D 4 334 ? 139.637 134.030 228.240 1.00 268.54 ? 334 ALA D N     1 
ATOM 4050 C CA    . ALA D 4 334 ? 139.404 133.126 229.361 1.00 268.31 ? 334 ALA D CA    1 
ATOM 4051 C C     . ALA D 4 334 ? 139.906 133.725 230.667 1.00 268.72 ? 334 ALA D C     1 
ATOM 4052 O O     . ALA D 4 334 ? 139.343 133.455 231.734 1.00 268.77 ? 334 ALA D O     1 
ATOM 4053 C CB    . ALA D 4 334 ? 140.076 131.778 229.099 1.00 267.67 ? 334 ALA D CB    1 
ATOM 4054 N N     . ARG D 4 335 ? 140.961 134.536 230.602 1.00 264.51 ? 335 ARG D N     1 
ATOM 4055 C CA    . ARG D 4 335 ? 141.450 135.282 231.753 1.00 263.68 ? 335 ARG D CA    1 
ATOM 4056 C C     . ARG D 4 335 ? 140.900 136.701 231.788 1.00 264.07 ? 335 ARG D C     1 
ATOM 4057 O O     . ARG D 4 335 ? 140.779 137.289 232.868 1.00 263.76 ? 335 ARG D O     1 
ATOM 4058 C CB    . ARG D 4 335 ? 142.982 135.320 231.736 1.00 262.78 ? 335 ARG D CB    1 
ATOM 4059 C CG    . ARG D 4 335 ? 143.623 133.991 231.359 1.00 262.51 ? 335 ARG D CG    1 
ATOM 4060 C CD    . ARG D 4 335 ? 143.987 133.957 229.879 1.00 261.64 ? 335 ARG D CD    1 
ATOM 4061 N NE    . ARG D 4 335 ? 144.524 132.665 229.470 1.00 260.75 ? 335 ARG D NE    1 
ATOM 4062 C CZ    . ARG D 4 335 ? 144.547 132.229 228.218 1.00 260.79 ? 335 ARG D CZ    1 
ATOM 4063 N NH1   . ARG D 4 335 ? 144.076 132.962 227.223 1.00 261.09 ? 335 ARG D NH1   1 
ATOM 4064 N NH2   . ARG D 4 335 ? 145.054 131.028 227.959 1.00 260.49 ? 335 ARG D NH2   1 
ATOM 4065 N N     . LYS D 4 336 ? 140.559 137.250 230.625 1.00 288.59 ? 336 LYS D N     1 
ATOM 4066 C CA    . LYS D 4 336 ? 139.986 138.581 230.485 1.00 288.67 ? 336 LYS D CA    1 
ATOM 4067 C C     . LYS D 4 336 ? 138.474 138.571 230.701 1.00 289.37 ? 336 LYS D C     1 
ATOM 4068 O O     . LYS D 4 336 ? 137.867 139.634 230.866 1.00 289.75 ? 336 LYS D O     1 
ATOM 4069 C CB    . LYS D 4 336 ? 140.370 139.126 229.094 1.00 288.04 ? 336 LYS D CB    1 
ATOM 4070 C CG    . LYS D 4 336 ? 139.638 140.337 228.513 1.00 287.89 ? 336 LYS D CG    1 
ATOM 4071 C CD    . LYS D 4 336 ? 139.608 141.539 229.438 1.00 287.68 ? 336 LYS D CD    1 
ATOM 4072 C CE    . LYS D 4 336 ? 138.338 142.336 229.203 1.00 288.26 ? 336 LYS D CE    1 
ATOM 4073 N NZ    . LYS D 4 336 ? 137.151 141.627 229.747 1.00 288.95 ? 336 LYS D NZ    1 
ATOM 4074 N N     . GLY D 4 337 ? 137.863 137.389 230.787 1.00 303.15 ? 337 GLY D N     1 
ATOM 4075 C CA    . GLY D 4 337 ? 136.431 137.302 231.011 1.00 302.69 ? 337 GLY D CA    1 
ATOM 4076 C C     . GLY D 4 337 ? 135.994 137.745 232.392 1.00 304.03 ? 337 GLY D C     1 
ATOM 4077 O O     . GLY D 4 337 ? 134.793 137.741 232.682 1.00 303.91 ? 337 GLY D O     1 
ATOM 4078 N N     . VAL D 4 338 ? 136.944 138.110 233.259 1.00 324.04 ? 338 VAL D N     1 
ATOM 4079 C CA    . VAL D 4 338 ? 136.592 138.636 234.576 1.00 324.34 ? 338 VAL D CA    1 
ATOM 4080 C C     . VAL D 4 338 ? 135.729 139.884 234.431 1.00 324.99 ? 338 VAL D C     1 
ATOM 4081 O O     . VAL D 4 338 ? 134.685 140.020 235.079 1.00 325.35 ? 338 VAL D O     1 
ATOM 4082 C CB    . VAL D 4 338 ? 137.863 138.920 235.397 1.00 323.59 ? 338 VAL D CB    1 
ATOM 4083 C CG1   . VAL D 4 338 ? 137.500 139.467 236.769 1.00 323.28 ? 338 VAL D CG1   1 
ATOM 4084 C CG2   . VAL D 4 338 ? 138.704 137.662 235.521 1.00 323.45 ? 338 VAL D CG2   1 
ATOM 4085 N N     . CYS D 4 339 ? 136.154 140.812 233.580 1.00 328.92 ? 339 CYS D N     1 
ATOM 4086 C CA    . CYS D 4 339 ? 135.285 141.915 233.204 1.00 328.64 ? 339 CYS D CA    1 
ATOM 4087 C C     . CYS D 4 339 ? 134.119 141.369 232.382 1.00 328.65 ? 339 CYS D C     1 
ATOM 4088 O O     . CYS D 4 339 ? 134.299 140.412 231.621 1.00 328.29 ? 339 CYS D O     1 
ATOM 4089 C CB    . CYS D 4 339 ? 136.065 142.964 232.410 1.00 328.15 ? 339 CYS D CB    1 
ATOM 4090 S SG    . CYS D 4 339 ? 137.608 143.488 233.190 1.00 328.14 ? 339 CYS D SG    1 
ATOM 4091 N N     . PRO D 4 340 ? 132.926 141.950 232.495 1.00 330.95 ? 340 PRO D N     1 
ATOM 4092 C CA    . PRO D 4 340 ? 131.717 141.275 231.993 1.00 330.37 ? 340 PRO D CA    1 
ATOM 4093 C C     . PRO D 4 340 ? 131.706 141.196 230.478 1.00 329.56 ? 340 PRO D C     1 
ATOM 4094 O O     . PRO D 4 340 ? 131.596 142.223 229.790 1.00 329.13 ? 340 PRO D O     1 
ATOM 4095 C CB    . PRO D 4 340 ? 130.566 142.153 232.514 1.00 330.12 ? 340 PRO D CB    1 
ATOM 4096 C CG    . PRO D 4 340 ? 131.195 143.349 233.172 1.00 330.39 ? 340 PRO D CG    1 
ATOM 4097 C CD    . PRO D 4 340 ? 132.661 143.339 232.903 1.00 330.55 ? 340 PRO D CD    1 
ATOM 4098 N N     . PRO D 4 341 ? 131.812 139.989 229.918 1.00 319.20 ? 341 PRO D N     1 
ATOM 4099 C CA    . PRO D 4 341 ? 131.727 139.844 228.462 1.00 319.00 ? 341 PRO D CA    1 
ATOM 4100 C C     . PRO D 4 341 ? 130.289 139.718 227.986 1.00 318.81 ? 341 PRO D C     1 
ATOM 4101 O O     . PRO D 4 341 ? 129.983 140.013 226.827 1.00 319.11 ? 341 PRO D O     1 
ATOM 4102 C CB    . PRO D 4 341 ? 132.523 138.562 228.200 1.00 319.06 ? 341 PRO D CB    1 
ATOM 4103 C CG    . PRO D 4 341 ? 132.302 137.741 229.440 1.00 319.04 ? 341 PRO D CG    1 
ATOM 4104 C CD    . PRO D 4 341 ? 132.034 138.694 230.588 1.00 319.21 ? 341 PRO D CD    1 
ATOM 4105 N N     . ALA D 4 342 ? 129.404 139.271 228.881 1.00 313.65 ? 342 ALA D N     1 
ATOM 4106 C CA    . ALA D 4 342 ? 128.003 139.084 228.519 1.00 313.65 ? 342 ALA D CA    1 
ATOM 4107 C C     . ALA D 4 342 ? 127.367 140.401 228.098 1.00 313.50 ? 342 ALA D C     1 
ATOM 4108 O O     . ALA D 4 342 ? 126.630 140.461 227.107 1.00 313.48 ? 342 ALA D O     1 
ATOM 4109 C CB    . ALA D 4 342 ? 127.238 138.462 229.687 1.00 313.62 ? 342 ALA D CB    1 
ATOM 4110 N N     . SER D 4 343 ? 127.639 141.472 228.846 1.00 307.91 ? 343 SER D N     1 
ATOM 4111 C CA    . SER D 4 343 ? 127.207 142.795 228.412 1.00 307.53 ? 343 SER D CA    1 
ATOM 4112 C C     . SER D 4 343 ? 127.897 143.190 227.114 1.00 307.74 ? 343 SER D C     1 
ATOM 4113 O O     . SER D 4 343 ? 127.270 143.763 226.215 1.00 307.77 ? 343 SER D O     1 
ATOM 4114 C CB    . SER D 4 343 ? 127.484 143.824 229.507 1.00 306.91 ? 343 SER D CB    1 
ATOM 4115 O OG    . SER D 4 343 ? 128.850 143.811 229.883 1.00 306.59 ? 343 SER D OG    1 
ATOM 4116 N N     . ALA D 4 344 ? 129.192 142.887 226.997 1.00 306.49 ? 344 ALA D N     1 
ATOM 4117 C CA    . ALA D 4 344 ? 129.918 143.183 225.767 1.00 306.54 ? 344 ALA D CA    1 
ATOM 4118 C C     . ALA D 4 344 ? 129.388 142.356 224.601 1.00 306.39 ? 344 ALA D C     1 
ATOM 4119 O O     . ALA D 4 344 ? 129.158 142.882 223.506 1.00 306.57 ? 344 ALA D O     1 
ATOM 4120 C CB    . ALA D 4 344 ? 131.413 142.935 225.970 1.00 306.43 ? 344 ALA D CB    1 
ATOM 4121 N N     . ASP D 4 345 ? 129.187 141.053 224.818 1.00 292.26 ? 345 ASP D N     1 
ATOM 4122 C CA    . ASP D 4 345 ? 128.680 140.199 223.749 1.00 291.06 ? 345 ASP D CA    1 
ATOM 4123 C C     . ASP D 4 345 ? 127.263 140.588 223.351 1.00 290.90 ? 345 ASP D C     1 
ATOM 4124 O O     . ASP D 4 345 ? 126.943 140.645 222.158 1.00 290.52 ? 345 ASP D O     1 
ATOM 4125 C CB    . ASP D 4 345 ? 128.735 138.731 224.171 1.00 290.20 ? 345 ASP D CB    1 
ATOM 4126 C CG    . ASP D 4 345 ? 130.153 138.214 224.293 1.00 290.09 ? 345 ASP D CG    1 
ATOM 4127 O OD1   . ASP D 4 345 ? 131.093 139.030 224.197 1.00 290.84 ? 345 ASP D OD1   1 
ATOM 4128 O OD2   . ASP D 4 345 ? 130.329 136.992 224.479 1.00 289.22 ? 345 ASP D OD2   1 
ATOM 4129 N N     . GLU D 4 346 ? 126.402 140.864 224.333 1.00 296.92 ? 346 GLU D N     1 
ATOM 4130 C CA    . GLU D 4 346 ? 125.032 141.258 224.025 1.00 297.17 ? 346 GLU D CA    1 
ATOM 4131 C C     . GLU D 4 346 ? 125.003 142.563 223.241 1.00 297.47 ? 346 GLU D C     1 
ATOM 4132 O O     . GLU D 4 346 ? 124.248 142.703 222.273 1.00 297.47 ? 346 GLU D O     1 
ATOM 4133 C CB    . GLU D 4 346 ? 124.217 141.385 225.312 1.00 297.63 ? 346 GLU D CB    1 
ATOM 4134 C CG    . GLU D 4 346 ? 122.746 141.729 225.106 1.00 297.64 ? 346 GLU D CG    1 
ATOM 4135 C CD    . GLU D 4 346 ? 122.034 140.768 224.171 1.00 296.95 ? 346 GLU D CD    1 
ATOM 4136 O OE1   . GLU D 4 346 ? 122.077 140.980 222.941 1.00 296.65 ? 346 GLU D OE1   1 
ATOM 4137 O OE2   . GLU D 4 346 ? 121.428 139.797 224.670 1.00 296.91 ? 346 GLU D OE2   1 
ATOM 4138 N N     . THR D 4 347 ? 125.828 143.531 223.644 1.00 294.40 ? 347 THR D N     1 
ATOM 4139 C CA    . THR D 4 347 ? 125.882 144.798 222.922 1.00 293.97 ? 347 THR D CA    1 
ATOM 4140 C C     . THR D 4 347 ? 126.401 144.601 221.504 1.00 293.39 ? 347 THR D C     1 
ATOM 4141 O O     . THR D 4 347 ? 125.952 145.277 220.571 1.00 293.56 ? 347 THR D O     1 
ATOM 4142 C CB    . THR D 4 347 ? 126.752 145.804 223.675 1.00 293.85 ? 347 THR D CB    1 
ATOM 4143 O OG1   . THR D 4 347 ? 127.926 145.148 224.170 1.00 294.29 ? 347 THR D OG1   1 
ATOM 4144 C CG2   . THR D 4 347 ? 125.982 146.412 224.840 1.00 293.43 ? 347 THR D CG2   1 
ATOM 4145 N N     . PHE D 4 348 ? 127.352 143.683 221.323 1.00 267.47 ? 348 PHE D N     1 
ATOM 4146 C CA    . PHE D 4 348 ? 127.912 143.456 219.995 1.00 266.35 ? 348 PHE D CA    1 
ATOM 4147 C C     . PHE D 4 348 ? 126.886 142.824 219.064 1.00 266.28 ? 348 PHE D C     1 
ATOM 4148 O O     . PHE D 4 348 ? 126.699 143.278 217.929 1.00 266.29 ? 348 PHE D O     1 
ATOM 4149 C CB    . PHE D 4 348 ? 129.156 142.573 220.094 1.00 265.37 ? 348 PHE D CB    1 
ATOM 4150 C CG    . PHE D 4 348 ? 129.571 141.962 218.785 1.00 264.42 ? 348 PHE D CG    1 
ATOM 4151 C CD1   . PHE D 4 348 ? 130.325 142.686 217.878 1.00 264.71 ? 348 PHE D CD1   1 
ATOM 4152 C CD2   . PHE D 4 348 ? 129.206 140.665 218.460 1.00 264.17 ? 348 PHE D CD2   1 
ATOM 4153 C CE1   . PHE D 4 348 ? 130.710 142.130 216.675 1.00 264.38 ? 348 PHE D CE1   1 
ATOM 4154 C CE2   . PHE D 4 348 ? 129.589 140.104 217.258 1.00 263.69 ? 348 PHE D CE2   1 
ATOM 4155 C CZ    . PHE D 4 348 ? 130.342 140.838 216.364 1.00 263.59 ? 348 PHE D CZ    1 
ATOM 4156 N N     . THR D 4 349 ? 126.208 141.770 219.528 1.00 269.63 ? 349 THR D N     1 
ATOM 4157 C CA    . THR D 4 349 ? 125.409 140.956 218.617 1.00 269.34 ? 349 THR D CA    1 
ATOM 4158 C C     . THR D 4 349 ? 124.239 141.741 218.034 1.00 269.44 ? 349 THR D C     1 
ATOM 4159 O O     . THR D 4 349 ? 123.935 141.610 216.843 1.00 269.08 ? 349 THR D O     1 
ATOM 4160 C CB    . THR D 4 349 ? 124.916 139.689 219.319 1.00 269.29 ? 349 THR D CB    1 
ATOM 4161 O OG1   . THR D 4 349 ? 124.004 138.993 218.460 1.00 269.43 ? 349 THR D OG1   1 
ATOM 4162 C CG2   . THR D 4 349 ? 124.217 140.022 220.624 1.00 269.77 ? 349 THR D CG2   1 
ATOM 4163 N N     . HIS D 4 350 ? 123.574 142.569 218.846 1.00 273.41 ? 350 HIS D N     1 
ATOM 4164 C CA    . HIS D 4 350 ? 122.409 143.277 218.327 1.00 273.77 ? 350 HIS D CA    1 
ATOM 4165 C C     . HIS D 4 350 ? 122.794 144.368 217.339 1.00 273.44 ? 350 HIS D C     1 
ATOM 4166 O O     . HIS D 4 350 ? 121.931 144.842 216.592 1.00 273.51 ? 350 HIS D O     1 
ATOM 4167 C CB    . HIS D 4 350 ? 121.562 143.862 219.466 1.00 273.93 ? 350 HIS D CB    1 
ATOM 4168 C CG    . HIS D 4 350 ? 122.261 144.892 220.301 1.00 273.99 ? 350 HIS D CG    1 
ATOM 4169 N ND1   . HIS D 4 350 ? 122.819 146.035 219.770 1.00 273.92 ? 350 HIS D ND1   1 
ATOM 4170 C CD2   . HIS D 4 350 ? 122.450 144.971 221.639 1.00 274.25 ? 350 HIS D CD2   1 
ATOM 4171 C CE1   . HIS D 4 350 ? 123.342 146.761 220.742 1.00 273.52 ? 350 HIS D CE1   1 
ATOM 4172 N NE2   . HIS D 4 350 ? 123.132 146.137 221.886 1.00 273.86 ? 350 HIS D NE2   1 
ATOM 4173 N N     . HIS D 4 351 ? 124.065 144.773 217.315 1.00 267.31 ? 351 HIS D N     1 
ATOM 4174 C CA    . HIS D 4 351 ? 124.504 145.788 216.364 1.00 266.98 ? 351 HIS D CA    1 
ATOM 4175 C C     . HIS D 4 351 ? 124.442 145.265 214.935 1.00 267.12 ? 351 HIS D C     1 
ATOM 4176 O O     . HIS D 4 351 ? 123.709 145.798 214.094 1.00 268.07 ? 351 HIS D O     1 
ATOM 4177 C CB    . HIS D 4 351 ? 125.921 146.249 216.707 1.00 267.04 ? 351 HIS D CB    1 
ATOM 4178 C CG    . HIS D 4 351 ? 125.986 147.189 217.869 1.00 267.47 ? 351 HIS D CG    1 
ATOM 4179 N ND1   . HIS D 4 351 ? 127.108 147.321 218.659 1.00 267.89 ? 351 HIS D ND1   1 
ATOM 4180 C CD2   . HIS D 4 351 ? 125.071 148.053 218.369 1.00 267.52 ? 351 HIS D CD2   1 
ATOM 4181 C CE1   . HIS D 4 351 ? 126.878 148.219 219.600 1.00 267.99 ? 351 HIS D CE1   1 
ATOM 4182 N NE2   . HIS D 4 351 ? 125.649 148.678 219.447 1.00 267.82 ? 351 HIS D NE2   1 
ATOM 4183 N N     . LEU D 4 352 ? 125.202 144.206 214.647 1.00 249.76 ? 352 LEU D N     1 
ATOM 4184 C CA    . LEU D 4 352 ? 125.351 143.754 213.266 1.00 249.71 ? 352 LEU D CA    1 
ATOM 4185 C C     . LEU D 4 352 ? 124.030 143.264 212.687 1.00 249.62 ? 352 LEU D C     1 
ATOM 4186 O O     . LEU D 4 352 ? 123.734 143.510 211.513 1.00 248.70 ? 352 LEU D O     1 
ATOM 4187 C CB    . LEU D 4 352 ? 126.411 142.657 213.182 1.00 248.55 ? 352 LEU D CB    1 
ATOM 4188 C CG    . LEU D 4 352 ? 126.165 141.409 214.029 1.00 247.80 ? 352 LEU D CG    1 
ATOM 4189 C CD1   . LEU D 4 352 ? 126.467 140.159 213.227 1.00 247.42 ? 352 LEU D CD1   1 
ATOM 4190 C CD2   . LEU D 4 352 ? 127.004 141.451 215.290 1.00 248.91 ? 352 LEU D CD2   1 
ATOM 4191 N N     . GLN D 4 353 ? 123.222 142.570 213.493 1.00 259.62 ? 353 GLN D N     1 
ATOM 4192 C CA    . GLN D 4 353 ? 122.013 141.945 212.965 1.00 260.64 ? 353 GLN D CA    1 
ATOM 4193 C C     . GLN D 4 353 ? 121.054 142.980 212.387 1.00 260.85 ? 353 GLN D C     1 
ATOM 4194 O O     . GLN D 4 353 ? 120.490 142.777 211.306 1.00 260.93 ? 353 GLN D O     1 
ATOM 4195 C CB    . GLN D 4 353 ? 121.335 141.111 214.053 1.00 261.17 ? 353 GLN D CB    1 
ATOM 4196 C CG    . GLN D 4 353 ? 121.126 141.834 215.372 1.00 260.91 ? 353 GLN D CG    1 
ATOM 4197 C CD    . GLN D 4 353 ? 119.786 142.532 215.458 1.00 261.19 ? 353 GLN D CD    1 
ATOM 4198 O OE1   . GLN D 4 353 ? 118.931 142.372 214.586 1.00 261.80 ? 353 GLN D OE1   1 
ATOM 4199 N NE2   . GLN D 4 353 ? 119.594 143.316 216.513 1.00 260.84 ? 353 GLN D NE2   1 
ATOM 4200 N N     . ARG D 4 354 ? 120.858 144.097 213.087 1.00 254.46 ? 354 ARG D N     1 
ATOM 4201 C CA    . ARG D 4 354 ? 120.097 145.194 212.500 1.00 253.97 ? 354 ARG D CA    1 
ATOM 4202 C C     . ARG D 4 354 ? 120.866 145.822 211.347 1.00 252.97 ? 354 ARG D C     1 
ATOM 4203 O O     . ARG D 4 354 ? 120.282 146.159 210.309 1.00 252.39 ? 354 ARG D O     1 
ATOM 4204 C CB    . ARG D 4 354 ? 119.768 146.238 213.567 1.00 253.86 ? 354 ARG D CB    1 
ATOM 4205 C CG    . ARG D 4 354 ? 118.653 145.823 214.513 1.00 253.87 ? 354 ARG D CG    1 
ATOM 4206 C CD    . ARG D 4 354 ? 117.284 146.177 213.953 1.00 253.74 ? 354 ARG D CD    1 
ATOM 4207 N NE    . ARG D 4 354 ? 116.203 145.534 214.692 1.00 253.05 ? 354 ARG D NE    1 
ATOM 4208 C CZ    . ARG D 4 354 ? 115.765 145.928 215.880 1.00 252.55 ? 354 ARG D CZ    1 
ATOM 4209 N NH1   . ARG D 4 354 ? 116.294 146.970 216.501 1.00 252.38 ? 354 ARG D NH1   1 
ATOM 4210 N NH2   . ARG D 4 354 ? 114.769 145.263 216.458 1.00 251.82 ? 354 ARG D NH2   1 
ATOM 4211 N N     . LEU D 4 355 ? 122.181 145.976 211.511 1.00 257.55 ? 355 LEU D N     1 
ATOM 4212 C CA    . LEU D 4 355 ? 123.008 146.516 210.439 1.00 258.10 ? 355 LEU D CA    1 
ATOM 4213 C C     . LEU D 4 355 ? 122.999 145.598 209.225 1.00 257.75 ? 355 LEU D C     1 
ATOM 4214 O O     . LEU D 4 355 ? 122.875 146.062 208.088 1.00 258.27 ? 355 LEU D O     1 
ATOM 4215 C CB    . LEU D 4 355 ? 124.435 146.739 210.938 1.00 258.80 ? 355 LEU D CB    1 
ATOM 4216 C CG    . LEU D 4 355 ? 124.638 147.941 211.861 1.00 259.18 ? 355 LEU D CG    1 
ATOM 4217 C CD1   . LEU D 4 355 ? 125.877 147.752 212.720 1.00 259.30 ? 355 LEU D CD1   1 
ATOM 4218 C CD2   . LEU D 4 355 ? 124.725 149.229 211.059 1.00 259.54 ? 355 LEU D CD2   1 
ATOM 4219 N N     . ARG D 4 356 ? 123.127 144.288 209.444 1.00 236.24 ? 356 ARG D N     1 
ATOM 4220 C CA    . ARG D 4 356 ? 123.103 143.360 208.319 1.00 235.95 ? 356 ARG D CA    1 
ATOM 4221 C C     . ARG D 4 356 ? 121.720 143.292 207.687 1.00 236.02 ? 356 ARG D C     1 
ATOM 4222 O O     . ARG D 4 356 ? 121.603 143.114 206.470 1.00 234.86 ? 356 ARG D O     1 
ATOM 4223 C CB    . ARG D 4 356 ? 123.567 141.974 208.768 1.00 235.16 ? 356 ARG D CB    1 
ATOM 4224 C CG    . ARG D 4 356 ? 125.071 141.877 208.967 1.00 233.98 ? 356 ARG D CG    1 
ATOM 4225 C CD    . ARG D 4 356 ? 125.499 140.482 209.385 1.00 233.60 ? 356 ARG D CD    1 
ATOM 4226 N NE    . ARG D 4 356 ? 126.949 140.374 209.489 1.00 233.42 ? 356 ARG D NE    1 
ATOM 4227 C CZ    . ARG D 4 356 ? 127.589 139.337 210.012 1.00 233.64 ? 356 ARG D CZ    1 
ATOM 4228 N NH1   . ARG D 4 356 ? 126.936 138.290 210.488 1.00 233.55 ? 356 ARG D NH1   1 
ATOM 4229 N NH2   . ARG D 4 356 ? 128.917 139.352 210.062 1.00 234.25 ? 356 ARG D NH2   1 
ATOM 4230 N N     . LYS D 4 357 ? 120.664 143.442 208.490 1.00 236.73 ? 357 LYS D N     1 
ATOM 4231 C CA    . LYS D 4 357 ? 119.319 143.510 207.928 1.00 235.97 ? 357 LYS D CA    1 
ATOM 4232 C C     . LYS D 4 357 ? 119.165 144.729 207.026 1.00 236.08 ? 357 LYS D C     1 
ATOM 4233 O O     . LYS D 4 357 ? 118.602 144.634 205.929 1.00 236.01 ? 357 LYS D O     1 
ATOM 4234 C CB    . LYS D 4 357 ? 118.286 143.535 209.054 1.00 235.40 ? 357 LYS D CB    1 
ATOM 4235 C CG    . LYS D 4 357 ? 116.973 142.847 208.721 1.00 234.91 ? 357 LYS D CG    1 
ATOM 4236 C CD    . LYS D 4 357 ? 116.079 142.762 209.947 1.00 234.03 ? 357 LYS D CD    1 
ATOM 4237 C CE    . LYS D 4 357 ? 114.810 141.982 209.656 1.00 233.84 ? 357 LYS D CE    1 
ATOM 4238 N NZ    . LYS D 4 357 ? 113.944 141.872 210.862 1.00 233.48 ? 357 LYS D NZ    1 
ATOM 4239 N N     . LEU D 4 358 ? 119.676 145.882 207.466 1.00 243.56 ? 358 LEU D N     1 
ATOM 4240 C CA    . LEU D 4 358 ? 119.618 147.077 206.630 1.00 243.75 ? 358 LEU D CA    1 
ATOM 4241 C C     . LEU D 4 358 ? 120.481 146.919 205.383 1.00 243.78 ? 358 LEU D C     1 
ATOM 4242 O O     . LEU D 4 358 ? 120.116 147.397 204.303 1.00 244.30 ? 358 LEU D O     1 
ATOM 4243 C CB    . LEU D 4 358 ? 120.050 148.302 207.436 1.00 243.84 ? 358 LEU D CB    1 
ATOM 4244 C CG    . LEU D 4 358 ? 120.073 149.646 206.703 1.00 243.66 ? 358 LEU D CG    1 
ATOM 4245 C CD1   . LEU D 4 358 ? 118.777 149.872 205.936 1.00 243.48 ? 358 LEU D CD1   1 
ATOM 4246 C CD2   . LEU D 4 358 ? 120.326 150.784 207.680 1.00 243.54 ? 358 LEU D CD2   1 
ATOM 4247 N N     . ILE D 4 359 ? 121.630 146.255 205.515 1.00 246.26 ? 359 ILE D N     1 
ATOM 4248 C CA    . ILE D 4 359 ? 122.487 146.005 204.360 1.00 246.89 ? 359 ILE D CA    1 
ATOM 4249 C C     . ILE D 4 359 ? 121.761 145.140 203.340 1.00 246.85 ? 359 ILE D C     1 
ATOM 4250 O O     . ILE D 4 359 ? 121.805 145.406 202.133 1.00 246.86 ? 359 ILE D O     1 
ATOM 4251 C CB    . ILE D 4 359 ? 123.811 145.358 204.808 1.00 246.89 ? 359 ILE D CB    1 
ATOM 4252 C CG1   . ILE D 4 359 ? 124.700 146.385 205.510 1.00 247.21 ? 359 ILE D CG1   1 
ATOM 4253 C CG2   . ILE D 4 359 ? 124.539 144.742 203.624 1.00 247.55 ? 359 ILE D CG2   1 
ATOM 4254 C CD1   . ILE D 4 359 ? 125.760 145.760 206.387 1.00 247.51 ? 359 ILE D CD1   1 
ATOM 4255 N N     . LYS D 4 360 ? 121.084 144.091 203.808 1.00 243.72 ? 360 LYS D N     1 
ATOM 4256 C CA    . LYS D 4 360 ? 120.318 143.242 202.905 1.00 244.62 ? 360 LYS D CA    1 
ATOM 4257 C C     . LYS D 4 360 ? 119.171 144.007 202.263 1.00 245.04 ? 360 LYS D C     1 
ATOM 4258 O O     . LYS D 4 360 ? 118.879 143.808 201.078 1.00 246.00 ? 360 LYS D O     1 
ATOM 4259 C CB    . LYS D 4 360 ? 119.794 142.018 203.655 1.00 244.08 ? 360 LYS D CB    1 
ATOM 4260 C CG    . LYS D 4 360 ? 119.749 140.749 202.818 1.00 243.49 ? 360 LYS D CG    1 
ATOM 4261 C CD    . LYS D 4 360 ? 119.403 139.539 203.670 1.00 242.53 ? 360 LYS D CD    1 
ATOM 4262 C CE    . LYS D 4 360 ? 118.678 138.482 202.857 1.00 242.36 ? 360 LYS D CE    1 
ATOM 4263 N NZ    . LYS D 4 360 ? 117.864 137.587 203.722 1.00 241.73 ? 360 LYS D NZ    1 
ATOM 4264 N N     . LYS D 4 361 ? 118.508 144.881 203.026 1.00 240.28 ? 361 LYS D N     1 
ATOM 4265 C CA    . LYS D 4 361 ? 117.449 145.706 202.451 1.00 239.74 ? 361 LYS D CA    1 
ATOM 4266 C C     . LYS D 4 361 ? 117.991 146.607 201.349 1.00 240.32 ? 361 LYS D C     1 
ATOM 4267 O O     . LYS D 4 361 ? 117.370 146.749 200.290 1.00 240.37 ? 361 LYS D O     1 
ATOM 4268 C CB    . LYS D 4 361 ? 116.782 146.540 203.544 1.00 238.66 ? 361 LYS D CB    1 
ATOM 4269 C CG    . LYS D 4 361 ? 115.303 146.798 203.313 1.00 238.67 ? 361 LYS D CG    1 
ATOM 4270 C CD    . LYS D 4 361 ? 114.665 147.468 204.520 1.00 238.22 ? 361 LYS D CD    1 
ATOM 4271 C CE    . LYS D 4 361 ? 113.158 147.570 204.364 1.00 237.66 ? 361 LYS D CE    1 
ATOM 4272 N NZ    . LYS D 4 361 ? 112.512 148.116 205.588 1.00 236.99 ? 361 LYS D NZ    1 
ATOM 4273 N N     . ARG D 4 362 ? 119.151 147.225 201.583 1.00 248.08 ? 362 ARG D N     1 
ATOM 4274 C CA    . ARG D 4 362 ? 119.756 148.082 200.568 1.00 248.54 ? 362 ARG D CA    1 
ATOM 4275 C C     . ARG D 4 362 ? 120.171 147.277 199.341 1.00 248.28 ? 362 ARG D C     1 
ATOM 4276 O O     . ARG D 4 362 ? 119.991 147.727 198.203 1.00 248.79 ? 362 ARG D O     1 
ATOM 4277 C CB    . ARG D 4 362 ? 120.957 148.820 201.158 1.00 247.63 ? 362 ARG D CB    1 
ATOM 4278 C CG    . ARG D 4 362 ? 121.375 150.061 200.385 1.00 247.29 ? 362 ARG D CG    1 
ATOM 4279 C CD    . ARG D 4 362 ? 120.377 151.193 200.568 1.00 247.55 ? 362 ARG D CD    1 
ATOM 4280 N NE    . ARG D 4 362 ? 120.345 152.087 199.417 1.00 247.80 ? 362 ARG D NE    1 
ATOM 4281 C CZ    . ARG D 4 362 ? 119.923 153.344 199.456 1.00 247.12 ? 362 ARG D CZ    1 
ATOM 4282 N NH1   . ARG D 4 362 ? 119.492 153.894 200.579 1.00 246.69 ? 362 ARG D NH1   1 
ATOM 4283 N NH2   . ARG D 4 362 ? 119.939 154.069 198.341 1.00 246.28 ? 362 ARG D NH2   1 
ATOM 4284 N N     . SER D 4 363 ? 120.731 146.085 199.553 1.00 248.81 ? 363 SER D N     1 
ATOM 4285 C CA    . SER D 4 363 ? 121.163 145.257 198.433 1.00 248.41 ? 363 SER D CA    1 
ATOM 4286 C C     . SER D 4 363 ? 119.976 144.803 197.597 1.00 248.33 ? 363 SER D C     1 
ATOM 4287 O O     . SER D 4 363 ? 120.090 144.649 196.375 1.00 249.01 ? 363 SER D O     1 
ATOM 4288 C CB    . SER D 4 363 ? 121.948 144.052 198.946 1.00 249.26 ? 363 SER D CB    1 
ATOM 4289 O OG    . SER D 4 363 ? 123.017 144.462 199.779 1.00 249.24 ? 363 SER D OG    1 
ATOM 4290 N N     . GLU D 4 364 ? 118.828 144.576 198.240 1.00 247.04 ? 364 GLU D N     1 
ATOM 4291 C CA    . GLU D 4 364 ? 117.621 144.225 197.501 1.00 247.66 ? 364 GLU D CA    1 
ATOM 4292 C C     . GLU D 4 364 ? 117.223 145.342 196.547 1.00 248.15 ? 364 GLU D C     1 
ATOM 4293 O O     . GLU D 4 364 ? 116.778 145.080 195.423 1.00 249.22 ? 364 GLU D O     1 
ATOM 4294 C CB    . GLU D 4 364 ? 116.485 143.912 198.474 1.00 247.84 ? 364 GLU D CB    1 
ATOM 4295 C CG    . GLU D 4 364 ? 115.169 143.563 197.804 1.00 248.26 ? 364 GLU D CG    1 
ATOM 4296 C CD    . GLU D 4 364 ? 114.081 144.578 198.097 1.00 248.04 ? 364 GLU D CD    1 
ATOM 4297 O OE1   . GLU D 4 364 ? 114.362 145.567 198.803 1.00 247.93 ? 364 GLU D OE1   1 
ATOM 4298 O OE2   . GLU D 4 364 ? 112.942 144.388 197.623 1.00 248.38 ? 364 GLU D OE2   1 
ATOM 4299 N N     . LEU D 4 365 ? 117.371 146.594 196.979 1.00 254.85 ? 365 LEU D N     1 
ATOM 4300 C CA    . LEU D 4 365 ? 117.168 147.718 196.073 1.00 255.66 ? 365 LEU D CA    1 
ATOM 4301 C C     . LEU D 4 365 ? 118.158 147.667 194.917 1.00 256.22 ? 365 LEU D C     1 
ATOM 4302 O O     . LEU D 4 365 ? 117.783 147.835 193.751 1.00 256.27 ? 365 LEU D O     1 
ATOM 4303 C CB    . LEU D 4 365 ? 117.305 149.042 196.830 1.00 257.06 ? 365 LEU D CB    1 
ATOM 4304 C CG    . LEU D 4 365 ? 116.199 149.597 197.737 1.00 257.64 ? 365 LEU D CG    1 
ATOM 4305 C CD1   . LEU D 4 365 ? 115.445 148.527 198.507 1.00 256.88 ? 365 LEU D CD1   1 
ATOM 4306 C CD2   . LEU D 4 365 ? 116.795 150.613 198.699 1.00 257.97 ? 365 LEU D CD2   1 
ATOM 4307 N N     . TYR D 4 366 ? 119.432 147.421 195.225 1.00 275.23 ? 366 TYR D N     1 
ATOM 4308 C CA    . TYR D 4 366 ? 120.458 147.429 194.188 1.00 276.43 ? 366 TYR D CA    1 
ATOM 4309 C C     . TYR D 4 366 ? 120.317 146.234 193.258 1.00 277.47 ? 366 TYR D C     1 
ATOM 4310 O O     . TYR D 4 366 ? 120.527 146.357 192.046 1.00 278.99 ? 366 TYR D O     1 
ATOM 4311 C CB    . TYR D 4 366 ? 121.844 147.458 194.827 1.00 276.56 ? 366 TYR D CB    1 
ATOM 4312 C CG    . TYR D 4 366 ? 122.383 148.856 194.988 1.00 277.02 ? 366 TYR D CG    1 
ATOM 4313 C CD1   . TYR D 4 366 ? 121.954 149.878 194.154 1.00 277.05 ? 366 TYR D CD1   1 
ATOM 4314 C CD2   . TYR D 4 366 ? 123.306 149.160 195.978 1.00 276.80 ? 366 TYR D CD2   1 
ATOM 4315 C CE1   . TYR D 4 366 ? 122.435 151.162 194.291 1.00 277.10 ? 366 TYR D CE1   1 
ATOM 4316 C CE2   . TYR D 4 366 ? 123.793 150.446 196.126 1.00 276.88 ? 366 TYR D CE2   1 
ATOM 4317 C CZ    . TYR D 4 366 ? 123.353 151.443 195.277 1.00 277.01 ? 366 TYR D CZ    1 
ATOM 4318 O OH    . TYR D 4 366 ? 123.827 152.729 195.410 1.00 276.60 ? 366 TYR D OH    1 
ATOM 4319 N N     . GLU D 4 367 ? 119.968 145.068 193.803 1.00 282.02 ? 367 GLU D N     1 
ATOM 4320 C CA    . GLU D 4 367 ? 119.779 143.896 192.957 1.00 282.22 ? 367 GLU D CA    1 
ATOM 4321 C C     . GLU D 4 367 ? 118.595 144.084 192.018 1.00 282.01 ? 367 GLU D C     1 
ATOM 4322 O O     . GLU D 4 367 ? 118.634 143.647 190.862 1.00 282.24 ? 367 GLU D O     1 
ATOM 4323 C CB    . GLU D 4 367 ? 119.589 142.649 193.818 1.00 282.15 ? 367 GLU D CB    1 
ATOM 4324 C CG    . GLU D 4 367 ? 119.651 141.307 193.076 1.00 282.11 ? 367 GLU D CG    1 
ATOM 4325 C CD    . GLU D 4 367 ? 120.810 141.186 192.093 1.00 282.12 ? 367 GLU D CD    1 
ATOM 4326 O OE1   . GLU D 4 367 ? 120.801 141.852 191.036 1.00 282.17 ? 367 GLU D OE1   1 
ATOM 4327 O OE2   . GLU D 4 367 ? 121.747 140.414 192.389 1.00 282.10 ? 367 GLU D OE2   1 
ATOM 4328 N N     . ALA D 4 368 ? 117.531 144.727 192.502 1.00 282.57 ? 368 ALA D N     1 
ATOM 4329 C CA    . ALA D 4 368 ? 116.378 144.998 191.650 1.00 282.84 ? 368 ALA D CA    1 
ATOM 4330 C C     . ALA D 4 368 ? 116.767 145.883 190.472 1.00 283.72 ? 368 ALA D C     1 
ATOM 4331 O O     . ALA D 4 368 ? 116.396 145.608 189.325 1.00 283.72 ? 368 ALA D O     1 
ATOM 4332 C CB    . ALA D 4 368 ? 115.263 145.647 192.471 1.00 282.01 ? 368 ALA D CB    1 
ATOM 4333 N N     . GLU D 4 369 ? 117.528 146.948 190.736 1.00 290.98 ? 369 GLU D N     1 
ATOM 4334 C CA    . GLU D 4 369 ? 118.002 147.801 189.650 1.00 290.59 ? 369 GLU D CA    1 
ATOM 4335 C C     . GLU D 4 369 ? 118.985 147.055 188.757 1.00 291.05 ? 369 GLU D C     1 
ATOM 4336 O O     . GLU D 4 369 ? 118.988 147.243 187.535 1.00 291.17 ? 369 GLU D O     1 
ATOM 4337 C CB    . GLU D 4 369 ? 118.638 149.072 190.213 1.00 290.28 ? 369 GLU D CB    1 
ATOM 4338 C CG    . GLU D 4 369 ? 118.463 150.292 189.322 1.00 289.74 ? 369 GLU D CG    1 
ATOM 4339 C CD    . GLU D 4 369 ? 119.262 151.491 189.797 1.00 289.79 ? 369 GLU D CD    1 
ATOM 4340 O OE1   . GLU D 4 369 ? 120.416 151.304 190.236 1.00 290.37 ? 369 GLU D OE1   1 
ATOM 4341 O OE2   . GLU D 4 369 ? 118.737 152.622 189.727 1.00 289.09 ? 369 GLU D OE2   1 
ATOM 4342 N N     . GLU D 4 370 ? 119.831 146.209 189.351 1.00 295.03 ? 370 GLU D N     1 
ATOM 4343 C CA    . GLU D 4 370 ? 120.729 145.383 188.552 1.00 294.44 ? 370 GLU D CA    1 
ATOM 4344 C C     . GLU D 4 370 ? 119.946 144.440 187.651 1.00 294.22 ? 370 GLU D C     1 
ATOM 4345 O O     . GLU D 4 370 ? 120.280 144.271 186.472 1.00 294.10 ? 370 GLU D O     1 
ATOM 4346 C CB    . GLU D 4 370 ? 121.667 144.593 189.463 1.00 294.27 ? 370 GLU D CB    1 
ATOM 4347 C CG    . GLU D 4 370 ? 122.876 144.008 188.753 1.00 293.71 ? 370 GLU D CG    1 
ATOM 4348 C CD    . GLU D 4 370 ? 123.184 142.591 189.199 1.00 293.53 ? 370 GLU D CD    1 
ATOM 4349 O OE1   . GLU D 4 370 ? 122.458 141.666 188.780 1.00 293.53 ? 370 GLU D OE1   1 
ATOM 4350 O OE2   . GLU D 4 370 ? 124.148 142.402 189.969 1.00 293.76 ? 370 GLU D OE2   1 
ATOM 4351 N N     . ARG D 4 371 ? 118.899 143.812 188.191 1.00 284.93 ? 371 ARG D N     1 
ATOM 4352 C CA    . ARG D 4 371 ? 118.033 142.979 187.365 1.00 284.00 ? 371 ARG D CA    1 
ATOM 4353 C C     . ARG D 4 371 ? 117.303 143.817 186.324 1.00 284.40 ? 371 ARG D C     1 
ATOM 4354 O O     . ARG D 4 371 ? 117.165 143.402 185.168 1.00 284.43 ? 371 ARG D O     1 
ATOM 4355 C CB    . ARG D 4 371 ? 117.037 142.226 188.245 1.00 283.40 ? 371 ARG D CB    1 
ATOM 4356 C CG    . ARG D 4 371 ? 116.461 140.977 187.605 1.00 282.95 ? 371 ARG D CG    1 
ATOM 4357 C CD    . ARG D 4 371 ? 115.829 140.077 188.650 1.00 283.06 ? 371 ARG D CD    1 
ATOM 4358 N NE    . ARG D 4 371 ? 114.918 140.812 189.518 1.00 282.96 ? 371 ARG D NE    1 
ATOM 4359 C CZ    . ARG D 4 371 ? 113.637 140.514 189.682 1.00 282.77 ? 371 ARG D CZ    1 
ATOM 4360 N NH1   . ARG D 4 371 ? 113.079 139.493 189.053 1.00 282.81 ? 371 ARG D NH1   1 
ATOM 4361 N NH2   . ARG D 4 371 ? 112.896 141.260 190.496 1.00 282.64 ? 371 ARG D NH2   1 
ATOM 4362 N N     . ALA D 4 372 ? 116.831 145.001 186.718 1.00 295.85 ? 372 ALA D N     1 
ATOM 4363 C CA    . ALA D 4 372 ? 116.127 145.871 185.781 1.00 296.65 ? 372 ALA D CA    1 
ATOM 4364 C C     . ALA D 4 372 ? 117.048 146.334 184.660 1.00 296.98 ? 372 ALA D C     1 
ATOM 4365 O O     . ALA D 4 372 ? 116.659 146.345 183.486 1.00 297.07 ? 372 ALA D O     1 
ATOM 4366 C CB    . ALA D 4 372 ? 115.534 147.068 186.524 1.00 296.57 ? 372 ALA D CB    1 
ATOM 4367 N N     . LEU D 4 373 ? 118.279 146.725 185.004 1.00 304.03 ? 373 LEU D N     1 
ATOM 4368 C CA    . LEU D 4 373 ? 119.233 147.131 183.976 1.00 303.70 ? 373 LEU D CA    1 
ATOM 4369 C C     . LEU D 4 373 ? 119.558 145.974 183.045 1.00 303.03 ? 373 LEU D C     1 
ATOM 4370 O O     . LEU D 4 373 ? 119.649 146.156 181.825 1.00 303.30 ? 373 LEU D O     1 
ATOM 4371 C CB    . LEU D 4 373 ? 120.509 147.677 184.616 1.00 304.00 ? 373 LEU D CB    1 
ATOM 4372 C CG    . LEU D 4 373 ? 120.504 149.168 184.956 1.00 304.11 ? 373 LEU D CG    1 
ATOM 4373 C CD1   . LEU D 4 373 ? 121.673 149.516 185.859 1.00 304.05 ? 373 LEU D CD1   1 
ATOM 4374 C CD2   . LEU D 4 373 ? 120.531 150.011 183.687 1.00 303.40 ? 373 LEU D CD2   1 
ATOM 4375 N N     . ARG D 4 374 ? 119.735 144.776 183.600 1.00 292.01 ? 374 ARG D N     1 
ATOM 4376 C CA    . ARG D 4 374 ? 119.943 143.603 182.761 1.00 292.08 ? 374 ARG D CA    1 
ATOM 4377 C C     . ARG D 4 374 ? 118.719 143.326 181.898 1.00 292.70 ? 374 ARG D C     1 
ATOM 4378 O O     . ARG D 4 374 ? 118.845 142.876 180.754 1.00 293.15 ? 374 ARG D O     1 
ATOM 4379 C CB    . ARG D 4 374 ? 120.282 142.393 183.631 1.00 291.46 ? 374 ARG D CB    1 
ATOM 4380 C CG    . ARG D 4 374 ? 121.753 142.299 184.007 1.00 291.00 ? 374 ARG D CG    1 
ATOM 4381 C CD    . ARG D 4 374 ? 122.086 140.947 184.615 1.00 291.28 ? 374 ARG D CD    1 
ATOM 4382 N NE    . ARG D 4 374 ? 121.807 140.913 186.046 1.00 291.66 ? 374 ARG D NE    1 
ATOM 4383 C CZ    . ARG D 4 374 ? 120.687 140.446 186.581 1.00 291.63 ? 374 ARG D CZ    1 
ATOM 4384 N NH1   . ARG D 4 374 ? 119.711 139.965 185.830 1.00 291.68 ? 374 ARG D NH1   1 
ATOM 4385 N NH2   . ARG D 4 374 ? 120.543 140.465 187.903 1.00 291.62 ? 374 ARG D NH2   1 
ATOM 4386 N N     . VAL D 4 375 ? 117.524 143.591 182.431 1.00 281.59 ? 375 VAL D N     1 
ATOM 4387 C CA    . VAL D 4 375 ? 116.301 143.391 181.658 1.00 280.27 ? 375 VAL D CA    1 
ATOM 4388 C C     . VAL D 4 375 ? 116.223 144.389 180.508 1.00 279.67 ? 375 VAL D C     1 
ATOM 4389 O O     . VAL D 4 375 ? 115.944 144.020 179.361 1.00 279.10 ? 375 VAL D O     1 
ATOM 4390 C CB    . VAL D 4 375 ? 115.067 143.485 182.573 1.00 279.19 ? 375 VAL D CB    1 
ATOM 4391 C CG1   . VAL D 4 375 ? 113.827 143.848 181.768 1.00 278.21 ? 375 VAL D CG1   1 
ATOM 4392 C CG2   . VAL D 4 375 ? 114.854 142.174 183.311 1.00 279.14 ? 375 VAL D CG2   1 
ATOM 4393 N N     . MET D 4 376 ? 116.474 145.668 180.795 1.00 264.07 ? 376 MET D N     1 
ATOM 4394 C CA    . MET D 4 376 ? 116.297 146.696 179.774 1.00 262.50 ? 376 MET D CA    1 
ATOM 4395 C C     . MET D 4 376 ? 117.423 146.658 178.746 1.00 262.87 ? 376 MET D C     1 
ATOM 4396 O O     . MET D 4 376 ? 117.171 146.754 177.539 1.00 262.21 ? 376 MET D O     1 
ATOM 4397 C CB    . MET D 4 376 ? 116.210 148.072 180.437 1.00 261.82 ? 376 MET D CB    1 
ATOM 4398 C CG    . MET D 4 376 ? 116.052 149.295 179.514 1.00 261.53 ? 376 MET D CG    1 
ATOM 4399 S SD    . MET D 4 376 ? 115.396 149.135 177.828 1.00 259.55 ? 376 MET D SD    1 
ATOM 4400 C CE    . MET D 4 376 ? 113.851 148.251 178.063 1.00 261.23 ? 376 MET D CE    1 
ATOM 4401 N N     . LEU D 4 377 ? 118.669 146.502 179.200 1.00 273.47 ? 377 LEU D N     1 
ATOM 4402 C CA    . LEU D 4 377 ? 119.808 146.586 178.288 1.00 273.17 ? 377 LEU D CA    1 
ATOM 4403 C C     . LEU D 4 377 ? 119.764 145.482 177.239 1.00 273.51 ? 377 LEU D C     1 
ATOM 4404 O O     . LEU D 4 377 ? 119.998 145.731 176.050 1.00 273.79 ? 377 LEU D O     1 
ATOM 4405 C CB    . LEU D 4 377 ? 121.118 146.528 179.072 1.00 273.85 ? 377 LEU D CB    1 
ATOM 4406 C CG    . LEU D 4 377 ? 121.835 147.860 179.295 1.00 274.23 ? 377 LEU D CG    1 
ATOM 4407 C CD1   . LEU D 4 377 ? 122.598 148.269 178.044 1.00 273.83 ? 377 LEU D CD1   1 
ATOM 4408 C CD2   . LEU D 4 377 ? 120.853 148.946 179.709 1.00 273.73 ? 377 LEU D CD2   1 
ATOM 4409 N N     . GLU D 4 378 ? 119.469 144.250 177.658 1.00 274.71 ? 378 GLU D N     1 
ATOM 4410 C CA    . GLU D 4 378 ? 119.353 143.165 176.692 1.00 275.33 ? 378 GLU D CA    1 
ATOM 4411 C C     . GLU D 4 378 ? 118.083 143.272 175.861 1.00 275.49 ? 378 GLU D C     1 
ATOM 4412 O O     . GLU D 4 378 ? 118.015 142.682 174.778 1.00 275.73 ? 378 GLU D O     1 
ATOM 4413 C CB    . GLU D 4 378 ? 119.410 141.808 177.397 1.00 275.53 ? 378 GLU D CB    1 
ATOM 4414 C CG    . GLU D 4 378 ? 120.759 141.489 178.030 1.00 274.58 ? 378 GLU D CG    1 
ATOM 4415 C CD    . GLU D 4 378 ? 120.650 140.497 179.171 1.00 274.74 ? 378 GLU D CD    1 
ATOM 4416 O OE1   . GLU D 4 378 ? 119.572 139.885 179.328 1.00 274.96 ? 378 GLU D OE1   1 
ATOM 4417 O OE2   . GLU D 4 378 ? 121.642 140.326 179.909 1.00 274.54 ? 378 GLU D OE2   1 
ATOM 4418 N N     . GLY D 4 379 ? 117.078 144.006 176.344 1.00 267.29 ? 379 GLY D N     1 
ATOM 4419 C CA    . GLY D 4 379 ? 115.885 144.232 175.547 1.00 266.42 ? 379 GLY D CA    1 
ATOM 4420 C C     . GLY D 4 379 ? 116.135 145.087 174.322 1.00 266.19 ? 379 GLY D C     1 
ATOM 4421 O O     . GLY D 4 379 ? 115.510 144.881 173.278 1.00 266.58 ? 379 GLY D O     1 
ATOM 4422 N N     . GLU D 4 380 ? 117.039 146.062 174.429 1.00 251.05 ? 380 GLU D N     1 
ATOM 4423 C CA    . GLU D 4 380 ? 117.299 146.962 173.313 1.00 250.42 ? 380 GLU D CA    1 
ATOM 4424 C C     . GLU D 4 380 ? 118.166 146.308 172.243 1.00 250.28 ? 380 GLU D C     1 
ATOM 4425 O O     . GLU D 4 380 ? 118.050 146.641 171.058 1.00 250.07 ? 380 GLU D O     1 
ATOM 4426 C CB    . GLU D 4 380 ? 117.964 148.243 173.820 1.00 250.10 ? 380 GLU D CB    1 
ATOM 4427 C CG    . GLU D 4 380 ? 117.050 149.136 174.645 1.00 249.98 ? 380 GLU D CG    1 
ATOM 4428 C CD    . GLU D 4 380 ? 115.769 149.498 173.921 1.00 250.46 ? 380 GLU D CD    1 
ATOM 4429 O OE1   . GLU D 4 380 ? 115.831 149.795 172.711 1.00 252.21 ? 380 GLU D OE1   1 
ATOM 4430 O OE2   . GLU D 4 380 ? 114.699 149.480 174.564 1.00 249.78 ? 380 GLU D OE2   1 
ATOM 4431 N N     . GLN D 4 381 ? 119.042 145.380 172.638 1.00 236.62 ? 381 GLN D N     1 
ATOM 4432 C CA    . GLN D 4 381 ? 120.054 144.873 171.715 1.00 235.12 ? 381 GLN D CA    1 
ATOM 4433 C C     . GLN D 4 381 ? 119.483 143.881 170.706 1.00 232.93 ? 381 GLN D C     1 
ATOM 4434 O O     . GLN D 4 381 ? 120.033 143.732 169.609 1.00 228.75 ? 381 GLN D O     1 
ATOM 4435 C CB    . GLN D 4 381 ? 121.207 144.255 172.504 1.00 235.20 ? 381 GLN D CB    1 
ATOM 4436 C CG    . GLN D 4 381 ? 121.960 145.282 173.338 1.00 234.61 ? 381 GLN D CG    1 
ATOM 4437 C CD    . GLN D 4 381 ? 122.602 144.688 174.570 1.00 234.98 ? 381 GLN D CD    1 
ATOM 4438 O OE1   . GLN D 4 381 ? 122.834 143.482 174.644 1.00 235.04 ? 381 GLN D OE1   1 
ATOM 4439 N NE2   . GLN D 4 381 ? 122.892 145.534 175.551 1.00 235.34 ? 381 GLN D NE2   1 
ATOM 4440 N N     . GLU D 4 382 ? 118.401 143.184 171.056 1.00 207.32 ? 382 GLU D N     1 
ATOM 4441 C CA    . GLU D 4 382 ? 117.789 142.266 170.102 1.00 203.80 ? 382 GLU D CA    1 
ATOM 4442 C C     . GLU D 4 382 ? 117.024 143.022 169.024 1.00 200.12 ? 382 GLU D C     1 
ATOM 4443 O O     . GLU D 4 382 ? 117.118 142.690 167.838 1.00 201.09 ? 382 GLU D O     1 
ATOM 4444 C CB    . GLU D 4 382 ? 116.858 141.293 170.828 1.00 203.95 ? 382 GLU D CB    1 
ATOM 4445 C CG    . GLU D 4 382 ? 117.409 140.726 172.130 1.00 203.98 ? 382 GLU D CG    1 
ATOM 4446 C CD    . GLU D 4 382 ? 118.870 140.344 172.038 1.00 203.82 ? 382 GLU D CD    1 
ATOM 4447 O OE1   . GLU D 4 382 ? 119.225 139.556 171.139 1.00 204.54 ? 382 GLU D OE1   1 
ATOM 4448 O OE2   . GLU D 4 382 ? 119.666 140.832 172.866 1.00 203.40 ? 382 GLU D OE2   1 
ATOM 4449 N N     . GLU D 4 383 ? 116.269 144.048 169.415 1.00 161.26 ? 383 GLU D N     1 
ATOM 4450 C CA    . GLU D 4 383 ? 115.395 144.727 168.466 1.00 158.00 ? 383 GLU D CA    1 
ATOM 4451 C C     . GLU D 4 383 ? 116.181 145.618 167.514 1.00 158.44 ? 383 GLU D C     1 
ATOM 4452 O O     . GLU D 4 383 ? 115.727 145.887 166.396 1.00 160.56 ? 383 GLU D O     1 
ATOM 4453 C CB    . GLU D 4 383 ? 114.341 145.541 169.211 1.00 160.05 ? 383 GLU D CB    1 
ATOM 4454 C CG    . GLU D 4 383 ? 113.194 146.019 168.339 1.00 158.75 ? 383 GLU D CG    1 
ATOM 4455 C CD    . GLU D 4 383 ? 112.793 145.003 167.288 1.00 160.03 ? 383 GLU D CD    1 
ATOM 4456 O OE1   . GLU D 4 383 ? 112.532 143.835 167.647 1.00 159.19 ? 383 GLU D OE1   1 
ATOM 4457 O OE2   . GLU D 4 383 ? 112.736 145.376 166.099 1.00 162.04 ? 383 GLU D OE2   1 
ATOM 4458 N N     . GLU D 4 384 ? 117.343 146.105 167.937 1.00 194.74 ? 384 GLU D N     1 
ATOM 4459 C CA    . GLU D 4 384 ? 118.154 146.940 167.061 1.00 199.27 ? 384 GLU D CA    1 
ATOM 4460 C C     . GLU D 4 384 ? 118.602 146.159 165.832 1.00 201.47 ? 384 GLU D C     1 
ATOM 4461 O O     . GLU D 4 384 ? 119.431 146.631 165.055 1.00 201.96 ? 384 GLU D O     1 
ATOM 4462 C CB    . GLU D 4 384 ? 119.379 147.489 167.788 1.00 201.20 ? 384 GLU D CB    1 
ATOM 4463 C CG    . GLU D 4 384 ? 120.393 146.432 168.162 1.00 200.45 ? 384 GLU D CG    1 
ATOM 4464 C CD    . GLU D 4 384 ? 121.283 146.866 169.303 1.00 202.72 ? 384 GLU D CD    1 
ATOM 4465 O OE1   . GLU D 4 384 ? 120.768 147.478 170.260 1.00 204.50 ? 384 GLU D OE1   1 
ATOM 4466 O OE2   . GLU D 4 384 ? 122.496 146.579 169.252 1.00 203.95 ? 384 GLU D OE2   1 
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