data_9GCH
# 
_entry.id   9GCH 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.400 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GCH         pdb_00009gch 10.2210/pdb9gch/pdb 
WWPDB D_1292140743 ?            ?                   
EMDB  EMD-51230    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-20 
2 'Structure model' 1 1 2024-11-27 
3 'Structure model' 1 2 2024-12-25 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
4 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 2 'Structure model' em_admin 
3 3 'Structure model' citation 
4 3 'Structure model' em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
2 2 'Structure model' '_citation.title'                   
3 2 'Structure model' '_em_admin.last_update'             
4 3 'Structure model' '_citation.journal_volume'          
5 3 'Structure model' '_citation.page_first'              
6 3 'Structure model' '_citation.page_last'               
7 3 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GCH 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Class from the same dataset additionally containing ELAC2' EMD-50052 'other EM volume'      
EMDB 'Human mitochondrial RNAseZ with tRNA-His-CCA'              EMD-51230 'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              martin.hallberg@ki.se 
_pdbx_contact_author.name_first         'B. Martin' 
_pdbx_contact_author.name_last          Hallberg 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6781-0345 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Valentin Gese, G.' 1 0000-0002-1890-5524 
'Hallberg, B.M.'    2 0000-0002-6781-0345 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Embo J.' 
_citation.journal_id_ASTM           EMJODG 
_citation.journal_id_CSD            0897 
_citation.journal_id_ISSN           1460-2075 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            43 
_citation.language                  ? 
_citation.page_first                6573 
_citation.page_last                 6590 
_citation.title                     
;Structural basis of 3'-tRNA maturation by the human mitochondrial RNase Z complex.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s44318-024-00297-w 
_citation.pdbx_database_id_PubMed   39516281 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Valentin Gese, G.' 1 ? 
primary 'Hallberg, B.M.'    2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man '3-hydroxyacyl-CoA dehydrogenase type-2' 26947.021 4 1.1.1.35,1.1.1.62,1.1.1.239,1.1.1.178,1.1.1.53,1.1.1.159 ? 
? ? 
2 polymer     man 'tRNA methyltransferase 10 homolog C'    42055.281 1 2.1.1.-,2.1.1.218,2.1.1.221                              ? 
? ? 
3 polymer     syn mt-tRNA-His-CCA                          22626.486 1 ?                                                        ? 
? ? 
4 non-polymer syn S-ADENOSYLMETHIONINE                     398.437   1 ?                                                        ? 
? ? 
5 non-polymer syn "GUANOSINE-5'-TRIPHOSPHATE"              523.180   1 ?                                                        ? 
? ? 
6 non-polymer syn 'MAGNESIUM ION'                          24.305    1 ?                                                        ? 
? ? 
7 water       nat water                                    18.015    9 ?                                                        ? 
? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 
;17-beta-estradiol 17-dehydrogenase,2-methyl-3-hydroxybutyryl-CoA dehydrogenase,MHBD,3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)),3-hydroxy-2-methylbutyryl-CoA dehydrogenase,3-hydroxyacyl-CoA dehydrogenase type II,3alpha(or 20beta)-hydroxysteroid dehydrogenase,7-alpha-hydroxysteroid dehydrogenase,Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,Mitochondrial ribonuclease P protein 2,Mitochondrial RNase P protein 2,Short chain dehydrogenase/reductase family 5C member 1,Short-chain type dehydrogenase/reductase XH98G2,Type II HADH
;
2 
;HBV pre-S2 trans-regulated protein 2,Mitochondrial ribonuclease P protein 1,Mitochondrial RNase P protein 1,RNA (guanine-9-)-methyltransferase domain-containing protein 1,Renal carcinoma antigen NY-REN-49,mRNA methyladenosine-N(1)-methyltransferase,tRNA (adenine(9)-N(1))-methyltransferase,tRNA (guanine(9)-N(1))-methyltransferase
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'   no no 
;MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKG
KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE
GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI
IENPFLNGEVIRLDGAIRMQP
;
;MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKG
KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE
GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI
IENPFLNGEVIRLDGAIRMQP
;
A,B,C,D ? 
2 'polypeptide(L)'   no no 
;MKSSVQEECVSTISSSKDEDPLAATREFIEMWRLLGREVPEHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIK
KEMKAAAREEAKNIKLLETTEEDKQKNFLFLRLWDRNMDIAMGWKGAQAMQFGQPLVFDMAYENYMKRKELQNTVSQLLE
SEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHVDLFPKDSIIYLTADSPNVMTTFRHDKVYVI
GSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGNKNLTLDQMIRILLCLKNNGNWQEALQFVPKRKHTGFLEISQ
HSQEFINRLKKAKTAENLYFQSHHHHHHDYKDDDDK
;
;MKSSVQEECVSTISSSKDEDPLAATREFIEMWRLLGREVPEHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIK
KEMKAAAREEAKNIKLLETTEEDKQKNFLFLRLWDRNMDIAMGWKGAQAMQFGQPLVFDMAYENYMKRKELQNTVSQLLE
SEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHVDLFPKDSIIYLTADSPNVMTTFRHDKVYVI
GSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGNKNLTLDQMIRILLCLKNNGNWQEALQFVPKRKHTGFLEISQ
HSQEFINRLKKAKTAENLYFQSHHHHHHDYKDDDDK
;
F       ? 
3 polyribonucleotide no no UAAAUAUAGUUUAACCAAAACAUCAGAUUGUGAAUCUGACAACAGAGGCUUACGACCCCUUAUUUACCCCA 
UAAAUAUAGUUUAACCAAAACAUCAGAUUGUGAAUCUGACAACAGAGGCUUACGACCCCUUAUUUACCCCA T       ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 S-ADENOSYLMETHIONINE        SAM 
5 "GUANOSINE-5'-TRIPHOSPHATE" GTP 
6 'MAGNESIUM ION'             MG  
7 water                       HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   ALA n 
1 4   ALA n 
1 5   CYS n 
1 6   ARG n 
1 7   SER n 
1 8   VAL n 
1 9   LYS n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  ALA n 
1 14  VAL n 
1 15  ILE n 
1 16  THR n 
1 17  GLY n 
1 18  GLY n 
1 19  ALA n 
1 20  SER n 
1 21  GLY n 
1 22  LEU n 
1 23  GLY n 
1 24  LEU n 
1 25  ALA n 
1 26  THR n 
1 27  ALA n 
1 28  GLU n 
1 29  ARG n 
1 30  LEU n 
1 31  VAL n 
1 32  GLY n 
1 33  GLN n 
1 34  GLY n 
1 35  ALA n 
1 36  SER n 
1 37  ALA n 
1 38  VAL n 
1 39  LEU n 
1 40  LEU n 
1 41  ASP n 
1 42  LEU n 
1 43  PRO n 
1 44  ASN n 
1 45  SER n 
1 46  GLY n 
1 47  GLY n 
1 48  GLU n 
1 49  ALA n 
1 50  GLN n 
1 51  ALA n 
1 52  LYS n 
1 53  LYS n 
1 54  LEU n 
1 55  GLY n 
1 56  ASN n 
1 57  ASN n 
1 58  CYS n 
1 59  VAL n 
1 60  PHE n 
1 61  ALA n 
1 62  PRO n 
1 63  ALA n 
1 64  ASP n 
1 65  VAL n 
1 66  THR n 
1 67  SER n 
1 68  GLU n 
1 69  LYS n 
1 70  ASP n 
1 71  VAL n 
1 72  GLN n 
1 73  THR n 
1 74  ALA n 
1 75  LEU n 
1 76  ALA n 
1 77  LEU n 
1 78  ALA n 
1 79  LYS n 
1 80  GLY n 
1 81  LYS n 
1 82  PHE n 
1 83  GLY n 
1 84  ARG n 
1 85  VAL n 
1 86  ASP n 
1 87  VAL n 
1 88  ALA n 
1 89  VAL n 
1 90  ASN n 
1 91  CYS n 
1 92  ALA n 
1 93  GLY n 
1 94  ILE n 
1 95  ALA n 
1 96  VAL n 
1 97  ALA n 
1 98  SER n 
1 99  LYS n 
1 100 THR n 
1 101 TYR n 
1 102 ASN n 
1 103 LEU n 
1 104 LYS n 
1 105 LYS n 
1 106 GLY n 
1 107 GLN n 
1 108 THR n 
1 109 HIS n 
1 110 THR n 
1 111 LEU n 
1 112 GLU n 
1 113 ASP n 
1 114 PHE n 
1 115 GLN n 
1 116 ARG n 
1 117 VAL n 
1 118 LEU n 
1 119 ASP n 
1 120 VAL n 
1 121 ASN n 
1 122 LEU n 
1 123 MET n 
1 124 GLY n 
1 125 THR n 
1 126 PHE n 
1 127 ASN n 
1 128 VAL n 
1 129 ILE n 
1 130 ARG n 
1 131 LEU n 
1 132 VAL n 
1 133 ALA n 
1 134 GLY n 
1 135 GLU n 
1 136 MET n 
1 137 GLY n 
1 138 GLN n 
1 139 ASN n 
1 140 GLU n 
1 141 PRO n 
1 142 ASP n 
1 143 GLN n 
1 144 GLY n 
1 145 GLY n 
1 146 GLN n 
1 147 ARG n 
1 148 GLY n 
1 149 VAL n 
1 150 ILE n 
1 151 ILE n 
1 152 ASN n 
1 153 THR n 
1 154 ALA n 
1 155 SER n 
1 156 VAL n 
1 157 ALA n 
1 158 ALA n 
1 159 PHE n 
1 160 GLU n 
1 161 GLY n 
1 162 GLN n 
1 163 VAL n 
1 164 GLY n 
1 165 GLN n 
1 166 ALA n 
1 167 ALA n 
1 168 TYR n 
1 169 SER n 
1 170 ALA n 
1 171 SER n 
1 172 LYS n 
1 173 GLY n 
1 174 GLY n 
1 175 ILE n 
1 176 VAL n 
1 177 GLY n 
1 178 MET n 
1 179 THR n 
1 180 LEU n 
1 181 PRO n 
1 182 ILE n 
1 183 ALA n 
1 184 ARG n 
1 185 ASP n 
1 186 LEU n 
1 187 ALA n 
1 188 PRO n 
1 189 ILE n 
1 190 GLY n 
1 191 ILE n 
1 192 ARG n 
1 193 VAL n 
1 194 MET n 
1 195 THR n 
1 196 ILE n 
1 197 ALA n 
1 198 PRO n 
1 199 GLY n 
1 200 LEU n 
1 201 PHE n 
1 202 GLY n 
1 203 THR n 
1 204 PRO n 
1 205 LEU n 
1 206 LEU n 
1 207 THR n 
1 208 SER n 
1 209 LEU n 
1 210 PRO n 
1 211 GLU n 
1 212 LYS n 
1 213 VAL n 
1 214 CYS n 
1 215 ASN n 
1 216 PHE n 
1 217 LEU n 
1 218 ALA n 
1 219 SER n 
1 220 GLN n 
1 221 VAL n 
1 222 PRO n 
1 223 PHE n 
1 224 PRO n 
1 225 SER n 
1 226 ARG n 
1 227 LEU n 
1 228 GLY n 
1 229 ASP n 
1 230 PRO n 
1 231 ALA n 
1 232 GLU n 
1 233 TYR n 
1 234 ALA n 
1 235 HIS n 
1 236 LEU n 
1 237 VAL n 
1 238 GLN n 
1 239 ALA n 
1 240 ILE n 
1 241 ILE n 
1 242 GLU n 
1 243 ASN n 
1 244 PRO n 
1 245 PHE n 
1 246 LEU n 
1 247 ASN n 
1 248 GLY n 
1 249 GLU n 
1 250 VAL n 
1 251 ILE n 
1 252 ARG n 
1 253 LEU n 
1 254 ASP n 
1 255 GLY n 
1 256 ALA n 
1 257 ILE n 
1 258 ARG n 
1 259 MET n 
1 260 GLN n 
1 261 PRO n 
2 1   MET n 
2 2   LYS n 
2 3   SER n 
2 4   SER n 
2 5   VAL n 
2 6   GLN n 
2 7   GLU n 
2 8   GLU n 
2 9   CYS n 
2 10  VAL n 
2 11  SER n 
2 12  THR n 
2 13  ILE n 
2 14  SER n 
2 15  SER n 
2 16  SER n 
2 17  LYS n 
2 18  ASP n 
2 19  GLU n 
2 20  ASP n 
2 21  PRO n 
2 22  LEU n 
2 23  ALA n 
2 24  ALA n 
2 25  THR n 
2 26  ARG n 
2 27  GLU n 
2 28  PHE n 
2 29  ILE n 
2 30  GLU n 
2 31  MET n 
2 32  TRP n 
2 33  ARG n 
2 34  LEU n 
2 35  LEU n 
2 36  GLY n 
2 37  ARG n 
2 38  GLU n 
2 39  VAL n 
2 40  PRO n 
2 41  GLU n 
2 42  HIS n 
2 43  ILE n 
2 44  THR n 
2 45  GLU n 
2 46  GLU n 
2 47  GLU n 
2 48  LEU n 
2 49  LYS n 
2 50  THR n 
2 51  LEU n 
2 52  MET n 
2 53  GLU n 
2 54  CYS n 
2 55  VAL n 
2 56  SER n 
2 57  ASN n 
2 58  THR n 
2 59  ALA n 
2 60  LYS n 
2 61  LYS n 
2 62  LYS n 
2 63  TYR n 
2 64  LEU n 
2 65  LYS n 
2 66  TYR n 
2 67  LEU n 
2 68  TYR n 
2 69  THR n 
2 70  LYS n 
2 71  GLU n 
2 72  LYS n 
2 73  VAL n 
2 74  LYS n 
2 75  LYS n 
2 76  ALA n 
2 77  ARG n 
2 78  GLN n 
2 79  ILE n 
2 80  LYS n 
2 81  LYS n 
2 82  GLU n 
2 83  MET n 
2 84  LYS n 
2 85  ALA n 
2 86  ALA n 
2 87  ALA n 
2 88  ARG n 
2 89  GLU n 
2 90  GLU n 
2 91  ALA n 
2 92  LYS n 
2 93  ASN n 
2 94  ILE n 
2 95  LYS n 
2 96  LEU n 
2 97  LEU n 
2 98  GLU n 
2 99  THR n 
2 100 THR n 
2 101 GLU n 
2 102 GLU n 
2 103 ASP n 
2 104 LYS n 
2 105 GLN n 
2 106 LYS n 
2 107 ASN n 
2 108 PHE n 
2 109 LEU n 
2 110 PHE n 
2 111 LEU n 
2 112 ARG n 
2 113 LEU n 
2 114 TRP n 
2 115 ASP n 
2 116 ARG n 
2 117 ASN n 
2 118 MET n 
2 119 ASP n 
2 120 ILE n 
2 121 ALA n 
2 122 MET n 
2 123 GLY n 
2 124 TRP n 
2 125 LYS n 
2 126 GLY n 
2 127 ALA n 
2 128 GLN n 
2 129 ALA n 
2 130 MET n 
2 131 GLN n 
2 132 PHE n 
2 133 GLY n 
2 134 GLN n 
2 135 PRO n 
2 136 LEU n 
2 137 VAL n 
2 138 PHE n 
2 139 ASP n 
2 140 MET n 
2 141 ALA n 
2 142 TYR n 
2 143 GLU n 
2 144 ASN n 
2 145 TYR n 
2 146 MET n 
2 147 LYS n 
2 148 ARG n 
2 149 LYS n 
2 150 GLU n 
2 151 LEU n 
2 152 GLN n 
2 153 ASN n 
2 154 THR n 
2 155 VAL n 
2 156 SER n 
2 157 GLN n 
2 158 LEU n 
2 159 LEU n 
2 160 GLU n 
2 161 SER n 
2 162 GLU n 
2 163 GLY n 
2 164 TRP n 
2 165 ASN n 
2 166 ARG n 
2 167 ARG n 
2 168 ASN n 
2 169 VAL n 
2 170 ASP n 
2 171 PRO n 
2 172 PHE n 
2 173 HIS n 
2 174 ILE n 
2 175 TYR n 
2 176 PHE n 
2 177 CYS n 
2 178 ASN n 
2 179 LEU n 
2 180 LYS n 
2 181 ILE n 
2 182 ASP n 
2 183 GLY n 
2 184 ALA n 
2 185 LEU n 
2 186 HIS n 
2 187 ARG n 
2 188 GLU n 
2 189 LEU n 
2 190 VAL n 
2 191 LYS n 
2 192 ARG n 
2 193 TYR n 
2 194 GLN n 
2 195 GLU n 
2 196 LYS n 
2 197 TRP n 
2 198 ASP n 
2 199 LYS n 
2 200 LEU n 
2 201 LEU n 
2 202 LEU n 
2 203 THR n 
2 204 SER n 
2 205 THR n 
2 206 GLU n 
2 207 LYS n 
2 208 SER n 
2 209 HIS n 
2 210 VAL n 
2 211 ASP n 
2 212 LEU n 
2 213 PHE n 
2 214 PRO n 
2 215 LYS n 
2 216 ASP n 
2 217 SER n 
2 218 ILE n 
2 219 ILE n 
2 220 TYR n 
2 221 LEU n 
2 222 THR n 
2 223 ALA n 
2 224 ASP n 
2 225 SER n 
2 226 PRO n 
2 227 ASN n 
2 228 VAL n 
2 229 MET n 
2 230 THR n 
2 231 THR n 
2 232 PHE n 
2 233 ARG n 
2 234 HIS n 
2 235 ASP n 
2 236 LYS n 
2 237 VAL n 
2 238 TYR n 
2 239 VAL n 
2 240 ILE n 
2 241 GLY n 
2 242 SER n 
2 243 PHE n 
2 244 VAL n 
2 245 ASP n 
2 246 LYS n 
2 247 SER n 
2 248 MET n 
2 249 GLN n 
2 250 PRO n 
2 251 GLY n 
2 252 THR n 
2 253 SER n 
2 254 LEU n 
2 255 ALA n 
2 256 LYS n 
2 257 ALA n 
2 258 LYS n 
2 259 ARG n 
2 260 LEU n 
2 261 ASN n 
2 262 LEU n 
2 263 ALA n 
2 264 THR n 
2 265 GLU n 
2 266 CYS n 
2 267 LEU n 
2 268 PRO n 
2 269 LEU n 
2 270 ASP n 
2 271 LYS n 
2 272 TYR n 
2 273 LEU n 
2 274 GLN n 
2 275 TRP n 
2 276 GLU n 
2 277 ILE n 
2 278 GLY n 
2 279 ASN n 
2 280 LYS n 
2 281 ASN n 
2 282 LEU n 
2 283 THR n 
2 284 LEU n 
2 285 ASP n 
2 286 GLN n 
2 287 MET n 
2 288 ILE n 
2 289 ARG n 
2 290 ILE n 
2 291 LEU n 
2 292 LEU n 
2 293 CYS n 
2 294 LEU n 
2 295 LYS n 
2 296 ASN n 
2 297 ASN n 
2 298 GLY n 
2 299 ASN n 
2 300 TRP n 
2 301 GLN n 
2 302 GLU n 
2 303 ALA n 
2 304 LEU n 
2 305 GLN n 
2 306 PHE n 
2 307 VAL n 
2 308 PRO n 
2 309 LYS n 
2 310 ARG n 
2 311 LYS n 
2 312 HIS n 
2 313 THR n 
2 314 GLY n 
2 315 PHE n 
2 316 LEU n 
2 317 GLU n 
2 318 ILE n 
2 319 SER n 
2 320 GLN n 
2 321 HIS n 
2 322 SER n 
2 323 GLN n 
2 324 GLU n 
2 325 PHE n 
2 326 ILE n 
2 327 ASN n 
2 328 ARG n 
2 329 LEU n 
2 330 LYS n 
2 331 LYS n 
2 332 ALA n 
2 333 LYS n 
2 334 THR n 
2 335 ALA n 
2 336 GLU n 
2 337 ASN n 
2 338 LEU n 
2 339 TYR n 
2 340 PHE n 
2 341 GLN n 
2 342 SER n 
2 343 HIS n 
2 344 HIS n 
2 345 HIS n 
2 346 HIS n 
2 347 HIS n 
2 348 HIS n 
2 349 ASP n 
2 350 TYR n 
2 351 LYS n 
2 352 ASP n 
2 353 ASP n 
2 354 ASP n 
2 355 ASP n 
2 356 LYS n 
3 1   U   n 
3 2   A   n 
3 3   A   n 
3 4   A   n 
3 5   U   n 
3 6   A   n 
3 7   U   n 
3 8   A   n 
3 9   G   n 
3 10  U   n 
3 11  U   n 
3 12  U   n 
3 13  A   n 
3 14  A   n 
3 15  C   n 
3 16  C   n 
3 17  A   n 
3 18  A   n 
3 19  A   n 
3 20  A   n 
3 21  C   n 
3 22  A   n 
3 23  U   n 
3 24  C   n 
3 25  A   n 
3 26  G   n 
3 27  A   n 
3 28  U   n 
3 29  U   n 
3 30  G   n 
3 31  U   n 
3 32  G   n 
3 33  A   n 
3 34  A   n 
3 35  U   n 
3 36  C   n 
3 37  U   n 
3 38  G   n 
3 39  A   n 
3 40  C   n 
3 41  A   n 
3 42  A   n 
3 43  C   n 
3 44  A   n 
3 45  G   n 
3 46  A   n 
3 47  G   n 
3 48  G   n 
3 49  C   n 
3 50  U   n 
3 51  U   n 
3 52  A   n 
3 53  C   n 
3 54  G   n 
3 55  A   n 
3 56  C   n 
3 57  C   n 
3 58  C   n 
3 59  C   n 
3 60  U   n 
3 61  U   n 
3 62  A   n 
3 63  U   n 
3 64  U   n 
3 65  U   n 
3 66  A   n 
3 67  C   n 
3 68  C   n 
3 69  C   n 
3 70  C   n 
3 71  A   n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 261 human ? 'HSD17B10, ERAB, HADH2, MRPP2, SCHAD, SDR5C1, XH98G2' ? ? ? ? ? ? 'Homo sapiens' 
9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 356 human ? 'TRMT10C, MRPP1, RG9MTD1'                             ? ? ? ? ? ? 'Homo sapiens' 
9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_src_syn.entity_id              3 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       71 
_pdbx_entity_src_syn.organism_scientific    'Homo sapiens' 
_pdbx_entity_src_syn.organism_common_name   human 
_pdbx_entity_src_syn.ncbi_taxonomy_id       9606 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P'   347.221 
ALA 'L-peptide linking' y ALANINE                      ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                     ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                   ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'              ? 'C4 H7 N O4'        133.103 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O8 P'    323.197 
CYS 'L-peptide linking' y CYSTEINE                     ? 'C3 H7 N O2 S'      121.158 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O8 P'   363.221 
GLN 'L-peptide linking' y GLUTAMINE                    ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'              ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                      ? 'C2 H5 N O2'        75.067  
GTP non-polymer         n "GUANOSINE-5'-TRIPHOSPHATE"  ? 'C10 H16 N5 O14 P3' 523.180 
HIS 'L-peptide linking' y HISTIDINE                    ? 'C6 H10 N3 O2 1'    156.162 
HOH non-polymer         . WATER                        ? 'H2 O'              18.015  
ILE 'L-peptide linking' y ISOLEUCINE                   ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                      ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                       ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                   ? 'C5 H11 N O2 S'     149.211 
MG  non-polymer         . 'MAGNESIUM ION'              ? 'Mg 2'              24.305  
PHE 'L-peptide linking' y PHENYLALANINE                ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                      ? 'C5 H9 N O2'        115.130 
SAM non-polymer         . S-ADENOSYLMETHIONINE         ? 'C15 H22 N6 O5 S'   398.437 
SER 'L-peptide linking' y SERINE                       ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                    ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                   ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                     ? 'C9 H11 N O3'       181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"   ? 'C9 H13 N2 O9 P'    324.181 
VAL 'L-peptide linking' y VALINE                       ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   ALA 3   3   ?   ?   ?   A . n 
A 1 4   ALA 4   4   ?   ?   ?   A . n 
A 1 5   CYS 5   5   ?   ?   ?   A . n 
A 1 6   ARG 6   6   ?   ?   ?   A . n 
A 1 7   SER 7   7   7   SER SER A . n 
A 1 8   VAL 8   8   8   VAL VAL A . n 
A 1 9   LYS 9   9   9   LYS LYS A . n 
A 1 10  GLY 10  10  10  GLY GLY A . n 
A 1 11  LEU 11  11  11  LEU LEU A . n 
A 1 12  VAL 12  12  12  VAL VAL A . n 
A 1 13  ALA 13  13  13  ALA ALA A . n 
A 1 14  VAL 14  14  14  VAL VAL A . n 
A 1 15  ILE 15  15  15  ILE ILE A . n 
A 1 16  THR 16  16  16  THR THR A . n 
A 1 17  GLY 17  17  17  GLY GLY A . n 
A 1 18  GLY 18  18  18  GLY GLY A . n 
A 1 19  ALA 19  19  19  ALA ALA A . n 
A 1 20  SER 20  20  20  SER SER A . n 
A 1 21  GLY 21  21  21  GLY GLY A . n 
A 1 22  LEU 22  22  22  LEU LEU A . n 
A 1 23  GLY 23  23  23  GLY GLY A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  ALA 25  25  25  ALA ALA A . n 
A 1 26  THR 26  26  26  THR THR A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  GLU 28  28  28  GLU GLU A . n 
A 1 29  ARG 29  29  29  ARG ARG A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  VAL 31  31  31  VAL VAL A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  GLN 33  33  33  GLN GLN A . n 
A 1 34  GLY 34  34  34  GLY GLY A . n 
A 1 35  ALA 35  35  35  ALA ALA A . n 
A 1 36  SER 36  36  36  SER SER A . n 
A 1 37  ALA 37  37  37  ALA ALA A . n 
A 1 38  VAL 38  38  38  VAL VAL A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  LEU 40  40  40  LEU LEU A . n 
A 1 41  ASP 41  41  41  ASP ASP A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  PRO 43  43  43  PRO PRO A . n 
A 1 44  ASN 44  44  44  ASN ASN A . n 
A 1 45  SER 45  45  45  SER SER A . n 
A 1 46  GLY 46  46  46  GLY GLY A . n 
A 1 47  GLY 47  47  47  GLY GLY A . n 
A 1 48  GLU 48  48  48  GLU GLU A . n 
A 1 49  ALA 49  49  49  ALA ALA A . n 
A 1 50  GLN 50  50  50  GLN GLN A . n 
A 1 51  ALA 51  51  51  ALA ALA A . n 
A 1 52  LYS 52  52  52  LYS LYS A . n 
A 1 53  LYS 53  53  53  LYS LYS A . n 
A 1 54  LEU 54  54  54  LEU LEU A . n 
A 1 55  GLY 55  55  55  GLY GLY A . n 
A 1 56  ASN 56  56  56  ASN ASN A . n 
A 1 57  ASN 57  57  57  ASN ASN A . n 
A 1 58  CYS 58  58  58  CYS CYS A . n 
A 1 59  VAL 59  59  59  VAL VAL A . n 
A 1 60  PHE 60  60  60  PHE PHE A . n 
A 1 61  ALA 61  61  61  ALA ALA A . n 
A 1 62  PRO 62  62  62  PRO PRO A . n 
A 1 63  ALA 63  63  63  ALA ALA A . n 
A 1 64  ASP 64  64  64  ASP ASP A . n 
A 1 65  VAL 65  65  65  VAL VAL A . n 
A 1 66  THR 66  66  66  THR THR A . n 
A 1 67  SER 67  67  67  SER SER A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  LYS 69  69  69  LYS LYS A . n 
A 1 70  ASP 70  70  70  ASP ASP A . n 
A 1 71  VAL 71  71  71  VAL VAL A . n 
A 1 72  GLN 72  72  72  GLN GLN A . n 
A 1 73  THR 73  73  73  THR THR A . n 
A 1 74  ALA 74  74  74  ALA ALA A . n 
A 1 75  LEU 75  75  75  LEU LEU A . n 
A 1 76  ALA 76  76  76  ALA ALA A . n 
A 1 77  LEU 77  77  77  LEU LEU A . n 
A 1 78  ALA 78  78  78  ALA ALA A . n 
A 1 79  LYS 79  79  79  LYS LYS A . n 
A 1 80  GLY 80  80  80  GLY GLY A . n 
A 1 81  LYS 81  81  81  LYS LYS A . n 
A 1 82  PHE 82  82  82  PHE PHE A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  ARG 84  84  84  ARG ARG A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  ASP 86  86  86  ASP ASP A . n 
A 1 87  VAL 87  87  87  VAL VAL A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  ASN 90  90  90  ASN ASN A . n 
A 1 91  CYS 91  91  91  CYS CYS A . n 
A 1 92  ALA 92  92  92  ALA ALA A . n 
A 1 93  GLY 93  93  93  GLY GLY A . n 
A 1 94  ILE 94  94  94  ILE ILE A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  VAL 96  96  96  VAL VAL A . n 
A 1 97  ALA 97  97  97  ALA ALA A . n 
A 1 98  SER 98  98  98  SER SER A . n 
A 1 99  LYS 99  99  99  LYS LYS A . n 
A 1 100 THR 100 100 100 THR THR A . n 
A 1 101 TYR 101 101 101 TYR TYR A . n 
A 1 102 ASN 102 102 102 ASN ASN A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 LYS 105 105 105 LYS LYS A . n 
A 1 106 GLY 106 106 106 GLY GLY A . n 
A 1 107 GLN 107 107 107 GLN GLN A . n 
A 1 108 THR 108 108 108 THR THR A . n 
A 1 109 HIS 109 109 109 HIS HIS A . n 
A 1 110 THR 110 110 110 THR THR A . n 
A 1 111 LEU 111 111 111 LEU LEU A . n 
A 1 112 GLU 112 112 112 GLU GLU A . n 
A 1 113 ASP 113 113 113 ASP ASP A . n 
A 1 114 PHE 114 114 114 PHE PHE A . n 
A 1 115 GLN 115 115 115 GLN GLN A . n 
A 1 116 ARG 116 116 116 ARG ARG A . n 
A 1 117 VAL 117 117 117 VAL VAL A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 ASP 119 119 119 ASP ASP A . n 
A 1 120 VAL 120 120 120 VAL VAL A . n 
A 1 121 ASN 121 121 121 ASN ASN A . n 
A 1 122 LEU 122 122 122 LEU LEU A . n 
A 1 123 MET 123 123 123 MET MET A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 THR 125 125 125 THR THR A . n 
A 1 126 PHE 126 126 126 PHE PHE A . n 
A 1 127 ASN 127 127 127 ASN ASN A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 ILE 129 129 129 ILE ILE A . n 
A 1 130 ARG 130 130 130 ARG ARG A . n 
A 1 131 LEU 131 131 131 LEU LEU A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 ALA 133 133 133 ALA ALA A . n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 GLU 135 135 135 GLU GLU A . n 
A 1 136 MET 136 136 136 MET MET A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 ASN 139 139 139 ASN ASN A . n 
A 1 140 GLU 140 140 140 GLU GLU A . n 
A 1 141 PRO 141 141 141 PRO PRO A . n 
A 1 142 ASP 142 142 142 ASP ASP A . n 
A 1 143 GLN 143 143 143 GLN GLN A . n 
A 1 144 GLY 144 144 144 GLY GLY A . n 
A 1 145 GLY 145 145 145 GLY GLY A . n 
A 1 146 GLN 146 146 146 GLN GLN A . n 
A 1 147 ARG 147 147 147 ARG ARG A . n 
A 1 148 GLY 148 148 148 GLY GLY A . n 
A 1 149 VAL 149 149 149 VAL VAL A . n 
A 1 150 ILE 150 150 150 ILE ILE A . n 
A 1 151 ILE 151 151 151 ILE ILE A . n 
A 1 152 ASN 152 152 152 ASN ASN A . n 
A 1 153 THR 153 153 153 THR THR A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 SER 155 155 155 SER SER A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 ALA 157 157 157 ALA ALA A . n 
A 1 158 ALA 158 158 158 ALA ALA A . n 
A 1 159 PHE 159 159 159 PHE PHE A . n 
A 1 160 GLU 160 160 160 GLU GLU A . n 
A 1 161 GLY 161 161 161 GLY GLY A . n 
A 1 162 GLN 162 162 162 GLN GLN A . n 
A 1 163 VAL 163 163 163 VAL VAL A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 GLN 165 165 165 GLN GLN A . n 
A 1 166 ALA 166 166 166 ALA ALA A . n 
A 1 167 ALA 167 167 167 ALA ALA A . n 
A 1 168 TYR 168 168 168 TYR TYR A . n 
A 1 169 SER 169 169 169 SER SER A . n 
A 1 170 ALA 170 170 170 ALA ALA A . n 
A 1 171 SER 171 171 171 SER SER A . n 
A 1 172 LYS 172 172 172 LYS LYS A . n 
A 1 173 GLY 173 173 173 GLY GLY A . n 
A 1 174 GLY 174 174 174 GLY GLY A . n 
A 1 175 ILE 175 175 175 ILE ILE A . n 
A 1 176 VAL 176 176 176 VAL VAL A . n 
A 1 177 GLY 177 177 177 GLY GLY A . n 
A 1 178 MET 178 178 178 MET MET A . n 
A 1 179 THR 179 179 179 THR THR A . n 
A 1 180 LEU 180 180 180 LEU LEU A . n 
A 1 181 PRO 181 181 181 PRO PRO A . n 
A 1 182 ILE 182 182 182 ILE ILE A . n 
A 1 183 ALA 183 183 183 ALA ALA A . n 
A 1 184 ARG 184 184 184 ARG ARG A . n 
A 1 185 ASP 185 185 185 ASP ASP A . n 
A 1 186 LEU 186 186 186 LEU LEU A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 PRO 188 188 188 PRO PRO A . n 
A 1 189 ILE 189 189 189 ILE ILE A . n 
A 1 190 GLY 190 190 190 GLY GLY A . n 
A 1 191 ILE 191 191 191 ILE ILE A . n 
A 1 192 ARG 192 192 192 ARG ARG A . n 
A 1 193 VAL 193 193 193 VAL VAL A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 ILE 196 196 196 ILE ILE A . n 
A 1 197 ALA 197 197 197 ALA ALA A . n 
A 1 198 PRO 198 198 198 PRO PRO A . n 
A 1 199 GLY 199 199 199 GLY GLY A . n 
A 1 200 LEU 200 200 200 LEU LEU A . n 
A 1 201 PHE 201 201 201 PHE PHE A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 THR 203 203 203 THR THR A . n 
A 1 204 PRO 204 204 204 PRO PRO A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 LEU 206 206 206 LEU LEU A . n 
A 1 207 THR 207 207 207 THR THR A . n 
A 1 208 SER 208 208 208 SER SER A . n 
A 1 209 LEU 209 209 209 LEU LEU A . n 
A 1 210 PRO 210 210 210 PRO PRO A . n 
A 1 211 GLU 211 211 211 GLU GLU A . n 
A 1 212 LYS 212 212 212 LYS LYS A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 CYS 214 214 214 CYS CYS A . n 
A 1 215 ASN 215 215 215 ASN ASN A . n 
A 1 216 PHE 216 216 216 PHE PHE A . n 
A 1 217 LEU 217 217 217 LEU LEU A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 SER 219 219 219 SER SER A . n 
A 1 220 GLN 220 220 220 GLN GLN A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 PRO 222 222 222 PRO PRO A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 PRO 224 224 224 PRO PRO A . n 
A 1 225 SER 225 225 225 SER SER A . n 
A 1 226 ARG 226 226 226 ARG ARG A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 PRO 230 230 230 PRO PRO A . n 
A 1 231 ALA 231 231 231 ALA ALA A . n 
A 1 232 GLU 232 232 232 GLU GLU A . n 
A 1 233 TYR 233 233 233 TYR TYR A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 HIS 235 235 235 HIS HIS A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 GLN 238 238 238 GLN GLN A . n 
A 1 239 ALA 239 239 239 ALA ALA A . n 
A 1 240 ILE 240 240 240 ILE ILE A . n 
A 1 241 ILE 241 241 241 ILE ILE A . n 
A 1 242 GLU 242 242 242 GLU GLU A . n 
A 1 243 ASN 243 243 243 ASN ASN A . n 
A 1 244 PRO 244 244 244 PRO PRO A . n 
A 1 245 PHE 245 245 245 PHE PHE A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 ASN 247 247 247 ASN ASN A . n 
A 1 248 GLY 248 248 248 GLY GLY A . n 
A 1 249 GLU 249 249 249 GLU GLU A . n 
A 1 250 VAL 250 250 250 VAL VAL A . n 
A 1 251 ILE 251 251 251 ILE ILE A . n 
A 1 252 ARG 252 252 252 ARG ARG A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 ASP 254 254 254 ASP ASP A . n 
A 1 255 GLY 255 255 255 GLY GLY A . n 
A 1 256 ALA 256 256 256 ALA ALA A . n 
A 1 257 ILE 257 257 257 ILE ILE A . n 
A 1 258 ARG 258 258 258 ARG ARG A . n 
A 1 259 MET 259 259 259 MET MET A . n 
A 1 260 GLN 260 260 260 GLN GLN A . n 
A 1 261 PRO 261 261 261 PRO PRO A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ALA 2   2   ?   ?   ?   B . n 
B 1 3   ALA 3   3   ?   ?   ?   B . n 
B 1 4   ALA 4   4   ?   ?   ?   B . n 
B 1 5   CYS 5   5   ?   ?   ?   B . n 
B 1 6   ARG 6   6   ?   ?   ?   B . n 
B 1 7   SER 7   7   7   SER SER B . n 
B 1 8   VAL 8   8   8   VAL VAL B . n 
B 1 9   LYS 9   9   9   LYS LYS B . n 
B 1 10  GLY 10  10  10  GLY GLY B . n 
B 1 11  LEU 11  11  11  LEU LEU B . n 
B 1 12  VAL 12  12  12  VAL VAL B . n 
B 1 13  ALA 13  13  13  ALA ALA B . n 
B 1 14  VAL 14  14  14  VAL VAL B . n 
B 1 15  ILE 15  15  15  ILE ILE B . n 
B 1 16  THR 16  16  16  THR THR B . n 
B 1 17  GLY 17  17  17  GLY GLY B . n 
B 1 18  GLY 18  18  18  GLY GLY B . n 
B 1 19  ALA 19  19  19  ALA ALA B . n 
B 1 20  SER 20  20  20  SER SER B . n 
B 1 21  GLY 21  21  21  GLY GLY B . n 
B 1 22  LEU 22  22  22  LEU LEU B . n 
B 1 23  GLY 23  23  23  GLY GLY B . n 
B 1 24  LEU 24  24  24  LEU LEU B . n 
B 1 25  ALA 25  25  25  ALA ALA B . n 
B 1 26  THR 26  26  26  THR THR B . n 
B 1 27  ALA 27  27  27  ALA ALA B . n 
B 1 28  GLU 28  28  28  GLU GLU B . n 
B 1 29  ARG 29  29  29  ARG ARG B . n 
B 1 30  LEU 30  30  30  LEU LEU B . n 
B 1 31  VAL 31  31  31  VAL VAL B . n 
B 1 32  GLY 32  32  32  GLY GLY B . n 
B 1 33  GLN 33  33  33  GLN GLN B . n 
B 1 34  GLY 34  34  34  GLY GLY B . n 
B 1 35  ALA 35  35  35  ALA ALA B . n 
B 1 36  SER 36  36  36  SER SER B . n 
B 1 37  ALA 37  37  37  ALA ALA B . n 
B 1 38  VAL 38  38  38  VAL VAL B . n 
B 1 39  LEU 39  39  39  LEU LEU B . n 
B 1 40  LEU 40  40  40  LEU LEU B . n 
B 1 41  ASP 41  41  41  ASP ASP B . n 
B 1 42  LEU 42  42  42  LEU LEU B . n 
B 1 43  PRO 43  43  43  PRO PRO B . n 
B 1 44  ASN 44  44  44  ASN ASN B . n 
B 1 45  SER 45  45  45  SER SER B . n 
B 1 46  GLY 46  46  46  GLY GLY B . n 
B 1 47  GLY 47  47  47  GLY GLY B . n 
B 1 48  GLU 48  48  48  GLU GLU B . n 
B 1 49  ALA 49  49  49  ALA ALA B . n 
B 1 50  GLN 50  50  50  GLN GLN B . n 
B 1 51  ALA 51  51  51  ALA ALA B . n 
B 1 52  LYS 52  52  52  LYS LYS B . n 
B 1 53  LYS 53  53  53  LYS LYS B . n 
B 1 54  LEU 54  54  54  LEU LEU B . n 
B 1 55  GLY 55  55  55  GLY GLY B . n 
B 1 56  ASN 56  56  56  ASN ASN B . n 
B 1 57  ASN 57  57  57  ASN ASN B . n 
B 1 58  CYS 58  58  58  CYS CYS B . n 
B 1 59  VAL 59  59  59  VAL VAL B . n 
B 1 60  PHE 60  60  60  PHE PHE B . n 
B 1 61  ALA 61  61  61  ALA ALA B . n 
B 1 62  PRO 62  62  62  PRO PRO B . n 
B 1 63  ALA 63  63  63  ALA ALA B . n 
B 1 64  ASP 64  64  64  ASP ASP B . n 
B 1 65  VAL 65  65  65  VAL VAL B . n 
B 1 66  THR 66  66  66  THR THR B . n 
B 1 67  SER 67  67  67  SER SER B . n 
B 1 68  GLU 68  68  68  GLU GLU B . n 
B 1 69  LYS 69  69  69  LYS LYS B . n 
B 1 70  ASP 70  70  70  ASP ASP B . n 
B 1 71  VAL 71  71  71  VAL VAL B . n 
B 1 72  GLN 72  72  72  GLN GLN B . n 
B 1 73  THR 73  73  73  THR THR B . n 
B 1 74  ALA 74  74  74  ALA ALA B . n 
B 1 75  LEU 75  75  75  LEU LEU B . n 
B 1 76  ALA 76  76  76  ALA ALA B . n 
B 1 77  LEU 77  77  77  LEU LEU B . n 
B 1 78  ALA 78  78  78  ALA ALA B . n 
B 1 79  LYS 79  79  79  LYS LYS B . n 
B 1 80  GLY 80  80  80  GLY GLY B . n 
B 1 81  LYS 81  81  81  LYS LYS B . n 
B 1 82  PHE 82  82  82  PHE PHE B . n 
B 1 83  GLY 83  83  83  GLY GLY B . n 
B 1 84  ARG 84  84  84  ARG ARG B . n 
B 1 85  VAL 85  85  85  VAL VAL B . n 
B 1 86  ASP 86  86  86  ASP ASP B . n 
B 1 87  VAL 87  87  87  VAL VAL B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  VAL 89  89  89  VAL VAL B . n 
B 1 90  ASN 90  90  90  ASN ASN B . n 
B 1 91  CYS 91  91  91  CYS CYS B . n 
B 1 92  ALA 92  92  92  ALA ALA B . n 
B 1 93  GLY 93  93  93  GLY GLY B . n 
B 1 94  ILE 94  94  94  ILE ILE B . n 
B 1 95  ALA 95  95  95  ALA ALA B . n 
B 1 96  VAL 96  96  96  VAL VAL B . n 
B 1 97  ALA 97  97  97  ALA ALA B . n 
B 1 98  SER 98  98  98  SER SER B . n 
B 1 99  LYS 99  99  99  LYS LYS B . n 
B 1 100 THR 100 100 100 THR THR B . n 
B 1 101 TYR 101 101 101 TYR TYR B . n 
B 1 102 ASN 102 102 102 ASN ASN B . n 
B 1 103 LEU 103 103 103 LEU LEU B . n 
B 1 104 LYS 104 104 104 LYS LYS B . n 
B 1 105 LYS 105 105 105 LYS LYS B . n 
B 1 106 GLY 106 106 106 GLY GLY B . n 
B 1 107 GLN 107 107 107 GLN GLN B . n 
B 1 108 THR 108 108 108 THR THR B . n 
B 1 109 HIS 109 109 109 HIS HIS B . n 
B 1 110 THR 110 110 110 THR THR B . n 
B 1 111 LEU 111 111 111 LEU LEU B . n 
B 1 112 GLU 112 112 112 GLU GLU B . n 
B 1 113 ASP 113 113 113 ASP ASP B . n 
B 1 114 PHE 114 114 114 PHE PHE B . n 
B 1 115 GLN 115 115 115 GLN GLN B . n 
B 1 116 ARG 116 116 116 ARG ARG B . n 
B 1 117 VAL 117 117 117 VAL VAL B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 ASP 119 119 119 ASP ASP B . n 
B 1 120 VAL 120 120 120 VAL VAL B . n 
B 1 121 ASN 121 121 121 ASN ASN B . n 
B 1 122 LEU 122 122 122 LEU LEU B . n 
B 1 123 MET 123 123 123 MET MET B . n 
B 1 124 GLY 124 124 124 GLY GLY B . n 
B 1 125 THR 125 125 125 THR THR B . n 
B 1 126 PHE 126 126 126 PHE PHE B . n 
B 1 127 ASN 127 127 127 ASN ASN B . n 
B 1 128 VAL 128 128 128 VAL VAL B . n 
B 1 129 ILE 129 129 129 ILE ILE B . n 
B 1 130 ARG 130 130 130 ARG ARG B . n 
B 1 131 LEU 131 131 131 LEU LEU B . n 
B 1 132 VAL 132 132 132 VAL VAL B . n 
B 1 133 ALA 133 133 133 ALA ALA B . n 
B 1 134 GLY 134 134 134 GLY GLY B . n 
B 1 135 GLU 135 135 135 GLU GLU B . n 
B 1 136 MET 136 136 136 MET MET B . n 
B 1 137 GLY 137 137 137 GLY GLY B . n 
B 1 138 GLN 138 138 138 GLN GLN B . n 
B 1 139 ASN 139 139 139 ASN ASN B . n 
B 1 140 GLU 140 140 140 GLU GLU B . n 
B 1 141 PRO 141 141 141 PRO PRO B . n 
B 1 142 ASP 142 142 142 ASP ASP B . n 
B 1 143 GLN 143 143 143 GLN GLN B . n 
B 1 144 GLY 144 144 144 GLY GLY B . n 
B 1 145 GLY 145 145 145 GLY GLY B . n 
B 1 146 GLN 146 146 146 GLN GLN B . n 
B 1 147 ARG 147 147 147 ARG ARG B . n 
B 1 148 GLY 148 148 148 GLY GLY B . n 
B 1 149 VAL 149 149 149 VAL VAL B . n 
B 1 150 ILE 150 150 150 ILE ILE B . n 
B 1 151 ILE 151 151 151 ILE ILE B . n 
B 1 152 ASN 152 152 152 ASN ASN B . n 
B 1 153 THR 153 153 153 THR THR B . n 
B 1 154 ALA 154 154 154 ALA ALA B . n 
B 1 155 SER 155 155 155 SER SER B . n 
B 1 156 VAL 156 156 156 VAL VAL B . n 
B 1 157 ALA 157 157 157 ALA ALA B . n 
B 1 158 ALA 158 158 158 ALA ALA B . n 
B 1 159 PHE 159 159 159 PHE PHE B . n 
B 1 160 GLU 160 160 160 GLU GLU B . n 
B 1 161 GLY 161 161 161 GLY GLY B . n 
B 1 162 GLN 162 162 162 GLN GLN B . n 
B 1 163 VAL 163 163 163 VAL VAL B . n 
B 1 164 GLY 164 164 164 GLY GLY B . n 
B 1 165 GLN 165 165 165 GLN GLN B . n 
B 1 166 ALA 166 166 166 ALA ALA B . n 
B 1 167 ALA 167 167 167 ALA ALA B . n 
B 1 168 TYR 168 168 168 TYR TYR B . n 
B 1 169 SER 169 169 169 SER SER B . n 
B 1 170 ALA 170 170 170 ALA ALA B . n 
B 1 171 SER 171 171 171 SER SER B . n 
B 1 172 LYS 172 172 172 LYS LYS B . n 
B 1 173 GLY 173 173 173 GLY GLY B . n 
B 1 174 GLY 174 174 174 GLY GLY B . n 
B 1 175 ILE 175 175 175 ILE ILE B . n 
B 1 176 VAL 176 176 176 VAL VAL B . n 
B 1 177 GLY 177 177 177 GLY GLY B . n 
B 1 178 MET 178 178 178 MET MET B . n 
B 1 179 THR 179 179 179 THR THR B . n 
B 1 180 LEU 180 180 180 LEU LEU B . n 
B 1 181 PRO 181 181 181 PRO PRO B . n 
B 1 182 ILE 182 182 182 ILE ILE B . n 
B 1 183 ALA 183 183 183 ALA ALA B . n 
B 1 184 ARG 184 184 184 ARG ARG B . n 
B 1 185 ASP 185 185 185 ASP ASP B . n 
B 1 186 LEU 186 186 186 LEU LEU B . n 
B 1 187 ALA 187 187 187 ALA ALA B . n 
B 1 188 PRO 188 188 188 PRO PRO B . n 
B 1 189 ILE 189 189 189 ILE ILE B . n 
B 1 190 GLY 190 190 190 GLY GLY B . n 
B 1 191 ILE 191 191 191 ILE ILE B . n 
B 1 192 ARG 192 192 192 ARG ARG B . n 
B 1 193 VAL 193 193 193 VAL VAL B . n 
B 1 194 MET 194 194 194 MET MET B . n 
B 1 195 THR 195 195 195 THR THR B . n 
B 1 196 ILE 196 196 196 ILE ILE B . n 
B 1 197 ALA 197 197 197 ALA ALA B . n 
B 1 198 PRO 198 198 198 PRO PRO B . n 
B 1 199 GLY 199 199 199 GLY GLY B . n 
B 1 200 LEU 200 200 200 LEU LEU B . n 
B 1 201 PHE 201 201 201 PHE PHE B . n 
B 1 202 GLY 202 202 202 GLY GLY B . n 
B 1 203 THR 203 203 203 THR THR B . n 
B 1 204 PRO 204 204 204 PRO PRO B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 LEU 206 206 206 LEU LEU B . n 
B 1 207 THR 207 207 207 THR THR B . n 
B 1 208 SER 208 208 208 SER SER B . n 
B 1 209 LEU 209 209 209 LEU LEU B . n 
B 1 210 PRO 210 210 210 PRO PRO B . n 
B 1 211 GLU 211 211 211 GLU GLU B . n 
B 1 212 LYS 212 212 212 LYS LYS B . n 
B 1 213 VAL 213 213 213 VAL VAL B . n 
B 1 214 CYS 214 214 214 CYS CYS B . n 
B 1 215 ASN 215 215 215 ASN ASN B . n 
B 1 216 PHE 216 216 216 PHE PHE B . n 
B 1 217 LEU 217 217 217 LEU LEU B . n 
B 1 218 ALA 218 218 218 ALA ALA B . n 
B 1 219 SER 219 219 219 SER SER B . n 
B 1 220 GLN 220 220 220 GLN GLN B . n 
B 1 221 VAL 221 221 221 VAL VAL B . n 
B 1 222 PRO 222 222 222 PRO PRO B . n 
B 1 223 PHE 223 223 223 PHE PHE B . n 
B 1 224 PRO 224 224 224 PRO PRO B . n 
B 1 225 SER 225 225 225 SER SER B . n 
B 1 226 ARG 226 226 226 ARG ARG B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 GLY 228 228 228 GLY GLY B . n 
B 1 229 ASP 229 229 229 ASP ASP B . n 
B 1 230 PRO 230 230 230 PRO PRO B . n 
B 1 231 ALA 231 231 231 ALA ALA B . n 
B 1 232 GLU 232 232 232 GLU GLU B . n 
B 1 233 TYR 233 233 233 TYR TYR B . n 
B 1 234 ALA 234 234 234 ALA ALA B . n 
B 1 235 HIS 235 235 235 HIS HIS B . n 
B 1 236 LEU 236 236 236 LEU LEU B . n 
B 1 237 VAL 237 237 237 VAL VAL B . n 
B 1 238 GLN 238 238 238 GLN GLN B . n 
B 1 239 ALA 239 239 239 ALA ALA B . n 
B 1 240 ILE 240 240 240 ILE ILE B . n 
B 1 241 ILE 241 241 241 ILE ILE B . n 
B 1 242 GLU 242 242 242 GLU GLU B . n 
B 1 243 ASN 243 243 243 ASN ASN B . n 
B 1 244 PRO 244 244 244 PRO PRO B . n 
B 1 245 PHE 245 245 245 PHE PHE B . n 
B 1 246 LEU 246 246 246 LEU LEU B . n 
B 1 247 ASN 247 247 247 ASN ASN B . n 
B 1 248 GLY 248 248 248 GLY GLY B . n 
B 1 249 GLU 249 249 249 GLU GLU B . n 
B 1 250 VAL 250 250 250 VAL VAL B . n 
B 1 251 ILE 251 251 251 ILE ILE B . n 
B 1 252 ARG 252 252 252 ARG ARG B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 ASP 254 254 254 ASP ASP B . n 
B 1 255 GLY 255 255 255 GLY GLY B . n 
B 1 256 ALA 256 256 256 ALA ALA B . n 
B 1 257 ILE 257 257 257 ILE ILE B . n 
B 1 258 ARG 258 258 258 ARG ARG B . n 
B 1 259 MET 259 259 259 MET MET B . n 
B 1 260 GLN 260 260 260 GLN GLN B . n 
B 1 261 PRO 261 261 261 PRO PRO B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   ALA 2   2   ?   ?   ?   C . n 
C 1 3   ALA 3   3   ?   ?   ?   C . n 
C 1 4   ALA 4   4   ?   ?   ?   C . n 
C 1 5   CYS 5   5   ?   ?   ?   C . n 
C 1 6   ARG 6   6   ?   ?   ?   C . n 
C 1 7   SER 7   7   7   SER SER C . n 
C 1 8   VAL 8   8   8   VAL VAL C . n 
C 1 9   LYS 9   9   9   LYS LYS C . n 
C 1 10  GLY 10  10  10  GLY GLY C . n 
C 1 11  LEU 11  11  11  LEU LEU C . n 
C 1 12  VAL 12  12  12  VAL VAL C . n 
C 1 13  ALA 13  13  13  ALA ALA C . n 
C 1 14  VAL 14  14  14  VAL VAL C . n 
C 1 15  ILE 15  15  15  ILE ILE C . n 
C 1 16  THR 16  16  16  THR THR C . n 
C 1 17  GLY 17  17  17  GLY GLY C . n 
C 1 18  GLY 18  18  18  GLY GLY C . n 
C 1 19  ALA 19  19  19  ALA ALA C . n 
C 1 20  SER 20  20  20  SER SER C . n 
C 1 21  GLY 21  21  21  GLY GLY C . n 
C 1 22  LEU 22  22  22  LEU LEU C . n 
C 1 23  GLY 23  23  23  GLY GLY C . n 
C 1 24  LEU 24  24  24  LEU LEU C . n 
C 1 25  ALA 25  25  25  ALA ALA C . n 
C 1 26  THR 26  26  26  THR THR C . n 
C 1 27  ALA 27  27  27  ALA ALA C . n 
C 1 28  GLU 28  28  28  GLU GLU C . n 
C 1 29  ARG 29  29  29  ARG ARG C . n 
C 1 30  LEU 30  30  30  LEU LEU C . n 
C 1 31  VAL 31  31  31  VAL VAL C . n 
C 1 32  GLY 32  32  32  GLY GLY C . n 
C 1 33  GLN 33  33  33  GLN GLN C . n 
C 1 34  GLY 34  34  34  GLY GLY C . n 
C 1 35  ALA 35  35  35  ALA ALA C . n 
C 1 36  SER 36  36  36  SER SER C . n 
C 1 37  ALA 37  37  37  ALA ALA C . n 
C 1 38  VAL 38  38  38  VAL VAL C . n 
C 1 39  LEU 39  39  39  LEU LEU C . n 
C 1 40  LEU 40  40  40  LEU LEU C . n 
C 1 41  ASP 41  41  41  ASP ASP C . n 
C 1 42  LEU 42  42  42  LEU LEU C . n 
C 1 43  PRO 43  43  43  PRO PRO C . n 
C 1 44  ASN 44  44  44  ASN ASN C . n 
C 1 45  SER 45  45  45  SER SER C . n 
C 1 46  GLY 46  46  46  GLY GLY C . n 
C 1 47  GLY 47  47  47  GLY GLY C . n 
C 1 48  GLU 48  48  48  GLU GLU C . n 
C 1 49  ALA 49  49  49  ALA ALA C . n 
C 1 50  GLN 50  50  50  GLN GLN C . n 
C 1 51  ALA 51  51  51  ALA ALA C . n 
C 1 52  LYS 52  52  52  LYS LYS C . n 
C 1 53  LYS 53  53  53  LYS LYS C . n 
C 1 54  LEU 54  54  54  LEU LEU C . n 
C 1 55  GLY 55  55  55  GLY GLY C . n 
C 1 56  ASN 56  56  56  ASN ASN C . n 
C 1 57  ASN 57  57  57  ASN ASN C . n 
C 1 58  CYS 58  58  58  CYS CYS C . n 
C 1 59  VAL 59  59  59  VAL VAL C . n 
C 1 60  PHE 60  60  60  PHE PHE C . n 
C 1 61  ALA 61  61  61  ALA ALA C . n 
C 1 62  PRO 62  62  62  PRO PRO C . n 
C 1 63  ALA 63  63  63  ALA ALA C . n 
C 1 64  ASP 64  64  64  ASP ASP C . n 
C 1 65  VAL 65  65  65  VAL VAL C . n 
C 1 66  THR 66  66  66  THR THR C . n 
C 1 67  SER 67  67  67  SER SER C . n 
C 1 68  GLU 68  68  68  GLU GLU C . n 
C 1 69  LYS 69  69  69  LYS LYS C . n 
C 1 70  ASP 70  70  70  ASP ASP C . n 
C 1 71  VAL 71  71  71  VAL VAL C . n 
C 1 72  GLN 72  72  72  GLN GLN C . n 
C 1 73  THR 73  73  73  THR THR C . n 
C 1 74  ALA 74  74  74  ALA ALA C . n 
C 1 75  LEU 75  75  75  LEU LEU C . n 
C 1 76  ALA 76  76  76  ALA ALA C . n 
C 1 77  LEU 77  77  77  LEU LEU C . n 
C 1 78  ALA 78  78  78  ALA ALA C . n 
C 1 79  LYS 79  79  79  LYS LYS C . n 
C 1 80  GLY 80  80  80  GLY GLY C . n 
C 1 81  LYS 81  81  81  LYS LYS C . n 
C 1 82  PHE 82  82  82  PHE PHE C . n 
C 1 83  GLY 83  83  83  GLY GLY C . n 
C 1 84  ARG 84  84  84  ARG ARG C . n 
C 1 85  VAL 85  85  85  VAL VAL C . n 
C 1 86  ASP 86  86  86  ASP ASP C . n 
C 1 87  VAL 87  87  87  VAL VAL C . n 
C 1 88  ALA 88  88  88  ALA ALA C . n 
C 1 89  VAL 89  89  89  VAL VAL C . n 
C 1 90  ASN 90  90  90  ASN ASN C . n 
C 1 91  CYS 91  91  91  CYS CYS C . n 
C 1 92  ALA 92  92  92  ALA ALA C . n 
C 1 93  GLY 93  93  93  GLY GLY C . n 
C 1 94  ILE 94  94  94  ILE ILE C . n 
C 1 95  ALA 95  95  95  ALA ALA C . n 
C 1 96  VAL 96  96  96  VAL VAL C . n 
C 1 97  ALA 97  97  97  ALA ALA C . n 
C 1 98  SER 98  98  98  SER SER C . n 
C 1 99  LYS 99  99  99  LYS LYS C . n 
C 1 100 THR 100 100 100 THR THR C . n 
C 1 101 TYR 101 101 101 TYR TYR C . n 
C 1 102 ASN 102 102 102 ASN ASN C . n 
C 1 103 LEU 103 103 103 LEU LEU C . n 
C 1 104 LYS 104 104 104 LYS LYS C . n 
C 1 105 LYS 105 105 105 LYS LYS C . n 
C 1 106 GLY 106 106 106 GLY GLY C . n 
C 1 107 GLN 107 107 107 GLN GLN C . n 
C 1 108 THR 108 108 108 THR THR C . n 
C 1 109 HIS 109 109 109 HIS HIS C . n 
C 1 110 THR 110 110 110 THR THR C . n 
C 1 111 LEU 111 111 111 LEU LEU C . n 
C 1 112 GLU 112 112 112 GLU GLU C . n 
C 1 113 ASP 113 113 113 ASP ASP C . n 
C 1 114 PHE 114 114 114 PHE PHE C . n 
C 1 115 GLN 115 115 115 GLN GLN C . n 
C 1 116 ARG 116 116 116 ARG ARG C . n 
C 1 117 VAL 117 117 117 VAL VAL C . n 
C 1 118 LEU 118 118 118 LEU LEU C . n 
C 1 119 ASP 119 119 119 ASP ASP C . n 
C 1 120 VAL 120 120 120 VAL VAL C . n 
C 1 121 ASN 121 121 121 ASN ASN C . n 
C 1 122 LEU 122 122 122 LEU LEU C . n 
C 1 123 MET 123 123 123 MET MET C . n 
C 1 124 GLY 124 124 124 GLY GLY C . n 
C 1 125 THR 125 125 125 THR THR C . n 
C 1 126 PHE 126 126 126 PHE PHE C . n 
C 1 127 ASN 127 127 127 ASN ASN C . n 
C 1 128 VAL 128 128 128 VAL VAL C . n 
C 1 129 ILE 129 129 129 ILE ILE C . n 
C 1 130 ARG 130 130 130 ARG ARG C . n 
C 1 131 LEU 131 131 131 LEU LEU C . n 
C 1 132 VAL 132 132 132 VAL VAL C . n 
C 1 133 ALA 133 133 133 ALA ALA C . n 
C 1 134 GLY 134 134 134 GLY GLY C . n 
C 1 135 GLU 135 135 135 GLU GLU C . n 
C 1 136 MET 136 136 136 MET MET C . n 
C 1 137 GLY 137 137 137 GLY GLY C . n 
C 1 138 GLN 138 138 138 GLN GLN C . n 
C 1 139 ASN 139 139 139 ASN ASN C . n 
C 1 140 GLU 140 140 140 GLU GLU C . n 
C 1 141 PRO 141 141 141 PRO PRO C . n 
C 1 142 ASP 142 142 142 ASP ASP C . n 
C 1 143 GLN 143 143 143 GLN GLN C . n 
C 1 144 GLY 144 144 144 GLY GLY C . n 
C 1 145 GLY 145 145 145 GLY GLY C . n 
C 1 146 GLN 146 146 146 GLN GLN C . n 
C 1 147 ARG 147 147 147 ARG ARG C . n 
C 1 148 GLY 148 148 148 GLY GLY C . n 
C 1 149 VAL 149 149 149 VAL VAL C . n 
C 1 150 ILE 150 150 150 ILE ILE C . n 
C 1 151 ILE 151 151 151 ILE ILE C . n 
C 1 152 ASN 152 152 152 ASN ASN C . n 
C 1 153 THR 153 153 153 THR THR C . n 
C 1 154 ALA 154 154 154 ALA ALA C . n 
C 1 155 SER 155 155 155 SER SER C . n 
C 1 156 VAL 156 156 156 VAL VAL C . n 
C 1 157 ALA 157 157 157 ALA ALA C . n 
C 1 158 ALA 158 158 158 ALA ALA C . n 
C 1 159 PHE 159 159 159 PHE PHE C . n 
C 1 160 GLU 160 160 160 GLU GLU C . n 
C 1 161 GLY 161 161 161 GLY GLY C . n 
C 1 162 GLN 162 162 162 GLN GLN C . n 
C 1 163 VAL 163 163 163 VAL VAL C . n 
C 1 164 GLY 164 164 164 GLY GLY C . n 
C 1 165 GLN 165 165 165 GLN GLN C . n 
C 1 166 ALA 166 166 166 ALA ALA C . n 
C 1 167 ALA 167 167 167 ALA ALA C . n 
C 1 168 TYR 168 168 168 TYR TYR C . n 
C 1 169 SER 169 169 169 SER SER C . n 
C 1 170 ALA 170 170 170 ALA ALA C . n 
C 1 171 SER 171 171 171 SER SER C . n 
C 1 172 LYS 172 172 172 LYS LYS C . n 
C 1 173 GLY 173 173 173 GLY GLY C . n 
C 1 174 GLY 174 174 174 GLY GLY C . n 
C 1 175 ILE 175 175 175 ILE ILE C . n 
C 1 176 VAL 176 176 176 VAL VAL C . n 
C 1 177 GLY 177 177 177 GLY GLY C . n 
C 1 178 MET 178 178 178 MET MET C . n 
C 1 179 THR 179 179 179 THR THR C . n 
C 1 180 LEU 180 180 180 LEU LEU C . n 
C 1 181 PRO 181 181 181 PRO PRO C . n 
C 1 182 ILE 182 182 182 ILE ILE C . n 
C 1 183 ALA 183 183 183 ALA ALA C . n 
C 1 184 ARG 184 184 184 ARG ARG C . n 
C 1 185 ASP 185 185 185 ASP ASP C . n 
C 1 186 LEU 186 186 186 LEU LEU C . n 
C 1 187 ALA 187 187 187 ALA ALA C . n 
C 1 188 PRO 188 188 188 PRO PRO C . n 
C 1 189 ILE 189 189 189 ILE ILE C . n 
C 1 190 GLY 190 190 190 GLY GLY C . n 
C 1 191 ILE 191 191 191 ILE ILE C . n 
C 1 192 ARG 192 192 192 ARG ARG C . n 
C 1 193 VAL 193 193 193 VAL VAL C . n 
C 1 194 MET 194 194 194 MET MET C . n 
C 1 195 THR 195 195 195 THR THR C . n 
C 1 196 ILE 196 196 196 ILE ILE C . n 
C 1 197 ALA 197 197 197 ALA ALA C . n 
C 1 198 PRO 198 198 198 PRO PRO C . n 
C 1 199 GLY 199 199 199 GLY GLY C . n 
C 1 200 LEU 200 200 200 LEU LEU C . n 
C 1 201 PHE 201 201 201 PHE PHE C . n 
C 1 202 GLY 202 202 202 GLY GLY C . n 
C 1 203 THR 203 203 203 THR THR C . n 
C 1 204 PRO 204 204 204 PRO PRO C . n 
C 1 205 LEU 205 205 205 LEU LEU C . n 
C 1 206 LEU 206 206 206 LEU LEU C . n 
C 1 207 THR 207 207 207 THR THR C . n 
C 1 208 SER 208 208 208 SER SER C . n 
C 1 209 LEU 209 209 209 LEU LEU C . n 
C 1 210 PRO 210 210 210 PRO PRO C . n 
C 1 211 GLU 211 211 211 GLU GLU C . n 
C 1 212 LYS 212 212 212 LYS LYS C . n 
C 1 213 VAL 213 213 213 VAL VAL C . n 
C 1 214 CYS 214 214 214 CYS CYS C . n 
C 1 215 ASN 215 215 215 ASN ASN C . n 
C 1 216 PHE 216 216 216 PHE PHE C . n 
C 1 217 LEU 217 217 217 LEU LEU C . n 
C 1 218 ALA 218 218 218 ALA ALA C . n 
C 1 219 SER 219 219 219 SER SER C . n 
C 1 220 GLN 220 220 220 GLN GLN C . n 
C 1 221 VAL 221 221 221 VAL VAL C . n 
C 1 222 PRO 222 222 222 PRO PRO C . n 
C 1 223 PHE 223 223 223 PHE PHE C . n 
C 1 224 PRO 224 224 224 PRO PRO C . n 
C 1 225 SER 225 225 225 SER SER C . n 
C 1 226 ARG 226 226 226 ARG ARG C . n 
C 1 227 LEU 227 227 227 LEU LEU C . n 
C 1 228 GLY 228 228 228 GLY GLY C . n 
C 1 229 ASP 229 229 229 ASP ASP C . n 
C 1 230 PRO 230 230 230 PRO PRO C . n 
C 1 231 ALA 231 231 231 ALA ALA C . n 
C 1 232 GLU 232 232 232 GLU GLU C . n 
C 1 233 TYR 233 233 233 TYR TYR C . n 
C 1 234 ALA 234 234 234 ALA ALA C . n 
C 1 235 HIS 235 235 235 HIS HIS C . n 
C 1 236 LEU 236 236 236 LEU LEU C . n 
C 1 237 VAL 237 237 237 VAL VAL C . n 
C 1 238 GLN 238 238 238 GLN GLN C . n 
C 1 239 ALA 239 239 239 ALA ALA C . n 
C 1 240 ILE 240 240 240 ILE ILE C . n 
C 1 241 ILE 241 241 241 ILE ILE C . n 
C 1 242 GLU 242 242 242 GLU GLU C . n 
C 1 243 ASN 243 243 243 ASN ASN C . n 
C 1 244 PRO 244 244 244 PRO PRO C . n 
C 1 245 PHE 245 245 245 PHE PHE C . n 
C 1 246 LEU 246 246 246 LEU LEU C . n 
C 1 247 ASN 247 247 247 ASN ASN C . n 
C 1 248 GLY 248 248 248 GLY GLY C . n 
C 1 249 GLU 249 249 249 GLU GLU C . n 
C 1 250 VAL 250 250 250 VAL VAL C . n 
C 1 251 ILE 251 251 251 ILE ILE C . n 
C 1 252 ARG 252 252 252 ARG ARG C . n 
C 1 253 LEU 253 253 253 LEU LEU C . n 
C 1 254 ASP 254 254 254 ASP ASP C . n 
C 1 255 GLY 255 255 255 GLY GLY C . n 
C 1 256 ALA 256 256 256 ALA ALA C . n 
C 1 257 ILE 257 257 257 ILE ILE C . n 
C 1 258 ARG 258 258 258 ARG ARG C . n 
C 1 259 MET 259 259 259 MET MET C . n 
C 1 260 GLN 260 260 260 GLN GLN C . n 
C 1 261 PRO 261 261 261 PRO PRO C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   ALA 2   2   ?   ?   ?   D . n 
D 1 3   ALA 3   3   ?   ?   ?   D . n 
D 1 4   ALA 4   4   ?   ?   ?   D . n 
D 1 5   CYS 5   5   ?   ?   ?   D . n 
D 1 6   ARG 6   6   ?   ?   ?   D . n 
D 1 7   SER 7   7   7   SER SER D . n 
D 1 8   VAL 8   8   8   VAL VAL D . n 
D 1 9   LYS 9   9   9   LYS LYS D . n 
D 1 10  GLY 10  10  10  GLY GLY D . n 
D 1 11  LEU 11  11  11  LEU LEU D . n 
D 1 12  VAL 12  12  12  VAL VAL D . n 
D 1 13  ALA 13  13  13  ALA ALA D . n 
D 1 14  VAL 14  14  14  VAL VAL D . n 
D 1 15  ILE 15  15  15  ILE ILE D . n 
D 1 16  THR 16  16  16  THR THR D . n 
D 1 17  GLY 17  17  17  GLY GLY D . n 
D 1 18  GLY 18  18  18  GLY GLY D . n 
D 1 19  ALA 19  19  19  ALA ALA D . n 
D 1 20  SER 20  20  20  SER SER D . n 
D 1 21  GLY 21  21  21  GLY GLY D . n 
D 1 22  LEU 22  22  22  LEU LEU D . n 
D 1 23  GLY 23  23  23  GLY GLY D . n 
D 1 24  LEU 24  24  24  LEU LEU D . n 
D 1 25  ALA 25  25  25  ALA ALA D . n 
D 1 26  THR 26  26  26  THR THR D . n 
D 1 27  ALA 27  27  27  ALA ALA D . n 
D 1 28  GLU 28  28  28  GLU GLU D . n 
D 1 29  ARG 29  29  29  ARG ARG D . n 
D 1 30  LEU 30  30  30  LEU LEU D . n 
D 1 31  VAL 31  31  31  VAL VAL D . n 
D 1 32  GLY 32  32  32  GLY GLY D . n 
D 1 33  GLN 33  33  33  GLN GLN D . n 
D 1 34  GLY 34  34  34  GLY GLY D . n 
D 1 35  ALA 35  35  35  ALA ALA D . n 
D 1 36  SER 36  36  36  SER SER D . n 
D 1 37  ALA 37  37  37  ALA ALA D . n 
D 1 38  VAL 38  38  38  VAL VAL D . n 
D 1 39  LEU 39  39  39  LEU LEU D . n 
D 1 40  LEU 40  40  40  LEU LEU D . n 
D 1 41  ASP 41  41  41  ASP ASP D . n 
D 1 42  LEU 42  42  42  LEU LEU D . n 
D 1 43  PRO 43  43  43  PRO PRO D . n 
D 1 44  ASN 44  44  44  ASN ASN D . n 
D 1 45  SER 45  45  45  SER SER D . n 
D 1 46  GLY 46  46  46  GLY GLY D . n 
D 1 47  GLY 47  47  47  GLY GLY D . n 
D 1 48  GLU 48  48  48  GLU GLU D . n 
D 1 49  ALA 49  49  49  ALA ALA D . n 
D 1 50  GLN 50  50  50  GLN GLN D . n 
D 1 51  ALA 51  51  51  ALA ALA D . n 
D 1 52  LYS 52  52  52  LYS LYS D . n 
D 1 53  LYS 53  53  53  LYS LYS D . n 
D 1 54  LEU 54  54  54  LEU LEU D . n 
D 1 55  GLY 55  55  55  GLY GLY D . n 
D 1 56  ASN 56  56  56  ASN ASN D . n 
D 1 57  ASN 57  57  57  ASN ASN D . n 
D 1 58  CYS 58  58  58  CYS CYS D . n 
D 1 59  VAL 59  59  59  VAL VAL D . n 
D 1 60  PHE 60  60  60  PHE PHE D . n 
D 1 61  ALA 61  61  61  ALA ALA D . n 
D 1 62  PRO 62  62  62  PRO PRO D . n 
D 1 63  ALA 63  63  63  ALA ALA D . n 
D 1 64  ASP 64  64  64  ASP ASP D . n 
D 1 65  VAL 65  65  65  VAL VAL D . n 
D 1 66  THR 66  66  66  THR THR D . n 
D 1 67  SER 67  67  67  SER SER D . n 
D 1 68  GLU 68  68  68  GLU GLU D . n 
D 1 69  LYS 69  69  69  LYS LYS D . n 
D 1 70  ASP 70  70  70  ASP ASP D . n 
D 1 71  VAL 71  71  71  VAL VAL D . n 
D 1 72  GLN 72  72  72  GLN GLN D . n 
D 1 73  THR 73  73  73  THR THR D . n 
D 1 74  ALA 74  74  74  ALA ALA D . n 
D 1 75  LEU 75  75  75  LEU LEU D . n 
D 1 76  ALA 76  76  76  ALA ALA D . n 
D 1 77  LEU 77  77  77  LEU LEU D . n 
D 1 78  ALA 78  78  78  ALA ALA D . n 
D 1 79  LYS 79  79  79  LYS LYS D . n 
D 1 80  GLY 80  80  80  GLY GLY D . n 
D 1 81  LYS 81  81  81  LYS LYS D . n 
D 1 82  PHE 82  82  82  PHE PHE D . n 
D 1 83  GLY 83  83  83  GLY GLY D . n 
D 1 84  ARG 84  84  84  ARG ARG D . n 
D 1 85  VAL 85  85  85  VAL VAL D . n 
D 1 86  ASP 86  86  86  ASP ASP D . n 
D 1 87  VAL 87  87  87  VAL VAL D . n 
D 1 88  ALA 88  88  88  ALA ALA D . n 
D 1 89  VAL 89  89  89  VAL VAL D . n 
D 1 90  ASN 90  90  90  ASN ASN D . n 
D 1 91  CYS 91  91  91  CYS CYS D . n 
D 1 92  ALA 92  92  92  ALA ALA D . n 
D 1 93  GLY 93  93  93  GLY GLY D . n 
D 1 94  ILE 94  94  94  ILE ILE D . n 
D 1 95  ALA 95  95  95  ALA ALA D . n 
D 1 96  VAL 96  96  96  VAL VAL D . n 
D 1 97  ALA 97  97  97  ALA ALA D . n 
D 1 98  SER 98  98  98  SER SER D . n 
D 1 99  LYS 99  99  99  LYS LYS D . n 
D 1 100 THR 100 100 100 THR THR D . n 
D 1 101 TYR 101 101 101 TYR TYR D . n 
D 1 102 ASN 102 102 102 ASN ASN D . n 
D 1 103 LEU 103 103 103 LEU LEU D . n 
D 1 104 LYS 104 104 104 LYS LYS D . n 
D 1 105 LYS 105 105 105 LYS LYS D . n 
D 1 106 GLY 106 106 106 GLY GLY D . n 
D 1 107 GLN 107 107 107 GLN GLN D . n 
D 1 108 THR 108 108 108 THR THR D . n 
D 1 109 HIS 109 109 109 HIS HIS D . n 
D 1 110 THR 110 110 110 THR THR D . n 
D 1 111 LEU 111 111 111 LEU LEU D . n 
D 1 112 GLU 112 112 112 GLU GLU D . n 
D 1 113 ASP 113 113 113 ASP ASP D . n 
D 1 114 PHE 114 114 114 PHE PHE D . n 
D 1 115 GLN 115 115 115 GLN GLN D . n 
D 1 116 ARG 116 116 116 ARG ARG D . n 
D 1 117 VAL 117 117 117 VAL VAL D . n 
D 1 118 LEU 118 118 118 LEU LEU D . n 
D 1 119 ASP 119 119 119 ASP ASP D . n 
D 1 120 VAL 120 120 120 VAL VAL D . n 
D 1 121 ASN 121 121 121 ASN ASN D . n 
D 1 122 LEU 122 122 122 LEU LEU D . n 
D 1 123 MET 123 123 123 MET MET D . n 
D 1 124 GLY 124 124 124 GLY GLY D . n 
D 1 125 THR 125 125 125 THR THR D . n 
D 1 126 PHE 126 126 126 PHE PHE D . n 
D 1 127 ASN 127 127 127 ASN ASN D . n 
D 1 128 VAL 128 128 128 VAL VAL D . n 
D 1 129 ILE 129 129 129 ILE ILE D . n 
D 1 130 ARG 130 130 130 ARG ARG D . n 
D 1 131 LEU 131 131 131 LEU LEU D . n 
D 1 132 VAL 132 132 132 VAL VAL D . n 
D 1 133 ALA 133 133 133 ALA ALA D . n 
D 1 134 GLY 134 134 134 GLY GLY D . n 
D 1 135 GLU 135 135 135 GLU GLU D . n 
D 1 136 MET 136 136 136 MET MET D . n 
D 1 137 GLY 137 137 137 GLY GLY D . n 
D 1 138 GLN 138 138 138 GLN GLN D . n 
D 1 139 ASN 139 139 139 ASN ASN D . n 
D 1 140 GLU 140 140 140 GLU GLU D . n 
D 1 141 PRO 141 141 141 PRO PRO D . n 
D 1 142 ASP 142 142 142 ASP ASP D . n 
D 1 143 GLN 143 143 143 GLN GLN D . n 
D 1 144 GLY 144 144 144 GLY GLY D . n 
D 1 145 GLY 145 145 145 GLY GLY D . n 
D 1 146 GLN 146 146 146 GLN GLN D . n 
D 1 147 ARG 147 147 147 ARG ARG D . n 
D 1 148 GLY 148 148 148 GLY GLY D . n 
D 1 149 VAL 149 149 149 VAL VAL D . n 
D 1 150 ILE 150 150 150 ILE ILE D . n 
D 1 151 ILE 151 151 151 ILE ILE D . n 
D 1 152 ASN 152 152 152 ASN ASN D . n 
D 1 153 THR 153 153 153 THR THR D . n 
D 1 154 ALA 154 154 154 ALA ALA D . n 
D 1 155 SER 155 155 155 SER SER D . n 
D 1 156 VAL 156 156 156 VAL VAL D . n 
D 1 157 ALA 157 157 157 ALA ALA D . n 
D 1 158 ALA 158 158 158 ALA ALA D . n 
D 1 159 PHE 159 159 159 PHE PHE D . n 
D 1 160 GLU 160 160 160 GLU GLU D . n 
D 1 161 GLY 161 161 161 GLY GLY D . n 
D 1 162 GLN 162 162 162 GLN GLN D . n 
D 1 163 VAL 163 163 163 VAL VAL D . n 
D 1 164 GLY 164 164 164 GLY GLY D . n 
D 1 165 GLN 165 165 165 GLN GLN D . n 
D 1 166 ALA 166 166 166 ALA ALA D . n 
D 1 167 ALA 167 167 167 ALA ALA D . n 
D 1 168 TYR 168 168 168 TYR TYR D . n 
D 1 169 SER 169 169 169 SER SER D . n 
D 1 170 ALA 170 170 170 ALA ALA D . n 
D 1 171 SER 171 171 171 SER SER D . n 
D 1 172 LYS 172 172 172 LYS LYS D . n 
D 1 173 GLY 173 173 173 GLY GLY D . n 
D 1 174 GLY 174 174 174 GLY GLY D . n 
D 1 175 ILE 175 175 175 ILE ILE D . n 
D 1 176 VAL 176 176 176 VAL VAL D . n 
D 1 177 GLY 177 177 177 GLY GLY D . n 
D 1 178 MET 178 178 178 MET MET D . n 
D 1 179 THR 179 179 179 THR THR D . n 
D 1 180 LEU 180 180 180 LEU LEU D . n 
D 1 181 PRO 181 181 181 PRO PRO D . n 
D 1 182 ILE 182 182 182 ILE ILE D . n 
D 1 183 ALA 183 183 183 ALA ALA D . n 
D 1 184 ARG 184 184 184 ARG ARG D . n 
D 1 185 ASP 185 185 185 ASP ASP D . n 
D 1 186 LEU 186 186 186 LEU LEU D . n 
D 1 187 ALA 187 187 187 ALA ALA D . n 
D 1 188 PRO 188 188 188 PRO PRO D . n 
D 1 189 ILE 189 189 189 ILE ILE D . n 
D 1 190 GLY 190 190 190 GLY GLY D . n 
D 1 191 ILE 191 191 191 ILE ILE D . n 
D 1 192 ARG 192 192 192 ARG ARG D . n 
D 1 193 VAL 193 193 193 VAL VAL D . n 
D 1 194 MET 194 194 194 MET MET D . n 
D 1 195 THR 195 195 195 THR THR D . n 
D 1 196 ILE 196 196 196 ILE ILE D . n 
D 1 197 ALA 197 197 197 ALA ALA D . n 
D 1 198 PRO 198 198 198 PRO PRO D . n 
D 1 199 GLY 199 199 199 GLY GLY D . n 
D 1 200 LEU 200 200 200 LEU LEU D . n 
D 1 201 PHE 201 201 201 PHE PHE D . n 
D 1 202 GLY 202 202 202 GLY GLY D . n 
D 1 203 THR 203 203 203 THR THR D . n 
D 1 204 PRO 204 204 204 PRO PRO D . n 
D 1 205 LEU 205 205 205 LEU LEU D . n 
D 1 206 LEU 206 206 206 LEU LEU D . n 
D 1 207 THR 207 207 207 THR THR D . n 
D 1 208 SER 208 208 208 SER SER D . n 
D 1 209 LEU 209 209 209 LEU LEU D . n 
D 1 210 PRO 210 210 210 PRO PRO D . n 
D 1 211 GLU 211 211 211 GLU GLU D . n 
D 1 212 LYS 212 212 212 LYS LYS D . n 
D 1 213 VAL 213 213 213 VAL VAL D . n 
D 1 214 CYS 214 214 214 CYS CYS D . n 
D 1 215 ASN 215 215 215 ASN ASN D . n 
D 1 216 PHE 216 216 216 PHE PHE D . n 
D 1 217 LEU 217 217 217 LEU LEU D . n 
D 1 218 ALA 218 218 218 ALA ALA D . n 
D 1 219 SER 219 219 219 SER SER D . n 
D 1 220 GLN 220 220 220 GLN GLN D . n 
D 1 221 VAL 221 221 221 VAL VAL D . n 
D 1 222 PRO 222 222 222 PRO PRO D . n 
D 1 223 PHE 223 223 223 PHE PHE D . n 
D 1 224 PRO 224 224 224 PRO PRO D . n 
D 1 225 SER 225 225 225 SER SER D . n 
D 1 226 ARG 226 226 226 ARG ARG D . n 
D 1 227 LEU 227 227 227 LEU LEU D . n 
D 1 228 GLY 228 228 228 GLY GLY D . n 
D 1 229 ASP 229 229 229 ASP ASP D . n 
D 1 230 PRO 230 230 230 PRO PRO D . n 
D 1 231 ALA 231 231 231 ALA ALA D . n 
D 1 232 GLU 232 232 232 GLU GLU D . n 
D 1 233 TYR 233 233 233 TYR TYR D . n 
D 1 234 ALA 234 234 234 ALA ALA D . n 
D 1 235 HIS 235 235 235 HIS HIS D . n 
D 1 236 LEU 236 236 236 LEU LEU D . n 
D 1 237 VAL 237 237 237 VAL VAL D . n 
D 1 238 GLN 238 238 238 GLN GLN D . n 
D 1 239 ALA 239 239 239 ALA ALA D . n 
D 1 240 ILE 240 240 240 ILE ILE D . n 
D 1 241 ILE 241 241 241 ILE ILE D . n 
D 1 242 GLU 242 242 242 GLU GLU D . n 
D 1 243 ASN 243 243 243 ASN ASN D . n 
D 1 244 PRO 244 244 244 PRO PRO D . n 
D 1 245 PHE 245 245 245 PHE PHE D . n 
D 1 246 LEU 246 246 246 LEU LEU D . n 
D 1 247 ASN 247 247 247 ASN ASN D . n 
D 1 248 GLY 248 248 248 GLY GLY D . n 
D 1 249 GLU 249 249 249 GLU GLU D . n 
D 1 250 VAL 250 250 250 VAL VAL D . n 
D 1 251 ILE 251 251 251 ILE ILE D . n 
D 1 252 ARG 252 252 252 ARG ARG D . n 
D 1 253 LEU 253 253 253 LEU LEU D . n 
D 1 254 ASP 254 254 254 ASP ASP D . n 
D 1 255 GLY 255 255 255 GLY GLY D . n 
D 1 256 ALA 256 256 256 ALA ALA D . n 
D 1 257 ILE 257 257 257 ILE ILE D . n 
D 1 258 ARG 258 258 258 ARG ARG D . n 
D 1 259 MET 259 259 259 MET MET D . n 
D 1 260 GLN 260 260 260 GLN GLN D . n 
D 1 261 PRO 261 261 261 PRO PRO D . n 
E 2 1   MET 1   70  ?   ?   ?   F . n 
E 2 2   LYS 2   71  ?   ?   ?   F . n 
E 2 3   SER 3   72  ?   ?   ?   F . n 
E 2 4   SER 4   73  ?   ?   ?   F . n 
E 2 5   VAL 5   74  ?   ?   ?   F . n 
E 2 6   GLN 6   75  ?   ?   ?   F . n 
E 2 7   GLU 7   76  ?   ?   ?   F . n 
E 2 8   GLU 8   77  ?   ?   ?   F . n 
E 2 9   CYS 9   78  ?   ?   ?   F . n 
E 2 10  VAL 10  79  ?   ?   ?   F . n 
E 2 11  SER 11  80  ?   ?   ?   F . n 
E 2 12  THR 12  81  ?   ?   ?   F . n 
E 2 13  ILE 13  82  ?   ?   ?   F . n 
E 2 14  SER 14  83  ?   ?   ?   F . n 
E 2 15  SER 15  84  ?   ?   ?   F . n 
E 2 16  SER 16  85  ?   ?   ?   F . n 
E 2 17  LYS 17  86  ?   ?   ?   F . n 
E 2 18  ASP 18  87  ?   ?   ?   F . n 
E 2 19  GLU 19  88  ?   ?   ?   F . n 
E 2 20  ASP 20  89  ?   ?   ?   F . n 
E 2 21  PRO 21  90  ?   ?   ?   F . n 
E 2 22  LEU 22  91  ?   ?   ?   F . n 
E 2 23  ALA 23  92  92  ALA ALA F . n 
E 2 24  ALA 24  93  93  ALA ALA F . n 
E 2 25  THR 25  94  94  THR THR F . n 
E 2 26  ARG 26  95  95  ARG ARG F . n 
E 2 27  GLU 27  96  96  GLU GLU F . n 
E 2 28  PHE 28  97  97  PHE PHE F . n 
E 2 29  ILE 29  98  98  ILE ILE F . n 
E 2 30  GLU 30  99  99  GLU GLU F . n 
E 2 31  MET 31  100 100 MET MET F . n 
E 2 32  TRP 32  101 101 TRP TRP F . n 
E 2 33  ARG 33  102 102 ARG ARG F . n 
E 2 34  LEU 34  103 103 LEU LEU F . n 
E 2 35  LEU 35  104 104 LEU LEU F . n 
E 2 36  GLY 36  105 105 GLY GLY F . n 
E 2 37  ARG 37  106 106 ARG ARG F . n 
E 2 38  GLU 38  107 107 GLU GLU F . n 
E 2 39  VAL 39  108 108 VAL VAL F . n 
E 2 40  PRO 40  109 109 PRO PRO F . n 
E 2 41  GLU 41  110 110 GLU GLU F . n 
E 2 42  HIS 42  111 111 HIS HIS F . n 
E 2 43  ILE 43  112 112 ILE ILE F . n 
E 2 44  THR 44  113 113 THR THR F . n 
E 2 45  GLU 45  114 114 GLU GLU F . n 
E 2 46  GLU 46  115 115 GLU GLU F . n 
E 2 47  GLU 47  116 116 GLU GLU F . n 
E 2 48  LEU 48  117 117 LEU LEU F . n 
E 2 49  LYS 49  118 118 LYS LYS F . n 
E 2 50  THR 50  119 119 THR THR F . n 
E 2 51  LEU 51  120 120 LEU LEU F . n 
E 2 52  MET 52  121 121 MET MET F . n 
E 2 53  GLU 53  122 122 GLU GLU F . n 
E 2 54  CYS 54  123 123 CYS CYS F . n 
E 2 55  VAL 55  124 124 VAL VAL F . n 
E 2 56  SER 56  125 125 SER SER F . n 
E 2 57  ASN 57  126 126 ASN ASN F . n 
E 2 58  THR 58  127 127 THR THR F . n 
E 2 59  ALA 59  128 128 ALA ALA F . n 
E 2 60  LYS 60  129 129 LYS LYS F . n 
E 2 61  LYS 61  130 130 LYS LYS F . n 
E 2 62  LYS 62  131 131 LYS LYS F . n 
E 2 63  TYR 63  132 132 TYR TYR F . n 
E 2 64  LEU 64  133 133 LEU LEU F . n 
E 2 65  LYS 65  134 134 LYS LYS F . n 
E 2 66  TYR 66  135 135 TYR TYR F . n 
E 2 67  LEU 67  136 136 LEU LEU F . n 
E 2 68  TYR 68  137 137 TYR TYR F . n 
E 2 69  THR 69  138 138 THR THR F . n 
E 2 70  LYS 70  139 139 LYS LYS F . n 
E 2 71  GLU 71  140 140 GLU GLU F . n 
E 2 72  LYS 72  141 141 LYS LYS F . n 
E 2 73  VAL 73  142 142 VAL VAL F . n 
E 2 74  LYS 74  143 143 LYS LYS F . n 
E 2 75  LYS 75  144 144 LYS LYS F . n 
E 2 76  ALA 76  145 145 ALA ALA F . n 
E 2 77  ARG 77  146 146 ARG ARG F . n 
E 2 78  GLN 78  147 147 GLN GLN F . n 
E 2 79  ILE 79  148 148 ILE ILE F . n 
E 2 80  LYS 80  149 149 LYS LYS F . n 
E 2 81  LYS 81  150 150 LYS LYS F . n 
E 2 82  GLU 82  151 151 GLU GLU F . n 
E 2 83  MET 83  152 152 MET MET F . n 
E 2 84  LYS 84  153 153 LYS LYS F . n 
E 2 85  ALA 85  154 154 ALA ALA F . n 
E 2 86  ALA 86  155 155 ALA ALA F . n 
E 2 87  ALA 87  156 156 ALA ALA F . n 
E 2 88  ARG 88  157 157 ARG ARG F . n 
E 2 89  GLU 89  158 158 GLU GLU F . n 
E 2 90  GLU 90  159 159 GLU GLU F . n 
E 2 91  ALA 91  160 160 ALA ALA F . n 
E 2 92  LYS 92  161 161 LYS LYS F . n 
E 2 93  ASN 93  162 162 ASN ASN F . n 
E 2 94  ILE 94  163 163 ILE ILE F . n 
E 2 95  LYS 95  164 164 LYS LYS F . n 
E 2 96  LEU 96  165 ?   ?   ?   F . n 
E 2 97  LEU 97  166 ?   ?   ?   F . n 
E 2 98  GLU 98  167 ?   ?   ?   F . n 
E 2 99  THR 99  168 ?   ?   ?   F . n 
E 2 100 THR 100 169 ?   ?   ?   F . n 
E 2 101 GLU 101 170 ?   ?   ?   F . n 
E 2 102 GLU 102 171 ?   ?   ?   F . n 
E 2 103 ASP 103 172 ?   ?   ?   F . n 
E 2 104 LYS 104 173 ?   ?   ?   F . n 
E 2 105 GLN 105 174 ?   ?   ?   F . n 
E 2 106 LYS 106 175 175 LYS LYS F . n 
E 2 107 ASN 107 176 176 ASN ASN F . n 
E 2 108 PHE 108 177 177 PHE PHE F . n 
E 2 109 LEU 109 178 178 LEU LEU F . n 
E 2 110 PHE 110 179 179 PHE PHE F . n 
E 2 111 LEU 111 180 180 LEU LEU F . n 
E 2 112 ARG 112 181 181 ARG ARG F . n 
E 2 113 LEU 113 182 182 LEU LEU F . n 
E 2 114 TRP 114 183 183 TRP TRP F . n 
E 2 115 ASP 115 184 184 ASP ASP F . n 
E 2 116 ARG 116 185 185 ARG ARG F . n 
E 2 117 ASN 117 186 186 ASN ASN F . n 
E 2 118 MET 118 187 187 MET MET F . n 
E 2 119 ASP 119 188 188 ASP ASP F . n 
E 2 120 ILE 120 189 189 ILE ILE F . n 
E 2 121 ALA 121 190 190 ALA ALA F . n 
E 2 122 MET 122 191 191 MET MET F . n 
E 2 123 GLY 123 192 192 GLY GLY F . n 
E 2 124 TRP 124 193 193 TRP TRP F . n 
E 2 125 LYS 125 194 194 LYS LYS F . n 
E 2 126 GLY 126 195 195 GLY GLY F . n 
E 2 127 ALA 127 196 196 ALA ALA F . n 
E 2 128 GLN 128 197 197 GLN GLN F . n 
E 2 129 ALA 129 198 198 ALA ALA F . n 
E 2 130 MET 130 199 199 MET MET F . n 
E 2 131 GLN 131 200 200 GLN GLN F . n 
E 2 132 PHE 132 201 201 PHE PHE F . n 
E 2 133 GLY 133 202 202 GLY GLY F . n 
E 2 134 GLN 134 203 203 GLN GLN F . n 
E 2 135 PRO 135 204 204 PRO PRO F . n 
E 2 136 LEU 136 205 205 LEU LEU F . n 
E 2 137 VAL 137 206 206 VAL VAL F . n 
E 2 138 PHE 138 207 207 PHE PHE F . n 
E 2 139 ASP 139 208 208 ASP ASP F . n 
E 2 140 MET 140 209 209 MET MET F . n 
E 2 141 ALA 141 210 210 ALA ALA F . n 
E 2 142 TYR 142 211 211 TYR TYR F . n 
E 2 143 GLU 143 212 212 GLU GLU F . n 
E 2 144 ASN 144 213 213 ASN ASN F . n 
E 2 145 TYR 145 214 214 TYR TYR F . n 
E 2 146 MET 146 215 215 MET MET F . n 
E 2 147 LYS 147 216 216 LYS LYS F . n 
E 2 148 ARG 148 217 217 ARG ARG F . n 
E 2 149 LYS 149 218 218 LYS LYS F . n 
E 2 150 GLU 150 219 219 GLU GLU F . n 
E 2 151 LEU 151 220 220 LEU LEU F . n 
E 2 152 GLN 152 221 221 GLN GLN F . n 
E 2 153 ASN 153 222 222 ASN ASN F . n 
E 2 154 THR 154 223 223 THR THR F . n 
E 2 155 VAL 155 224 224 VAL VAL F . n 
E 2 156 SER 156 225 225 SER SER F . n 
E 2 157 GLN 157 226 226 GLN GLN F . n 
E 2 158 LEU 158 227 227 LEU LEU F . n 
E 2 159 LEU 159 228 228 LEU LEU F . n 
E 2 160 GLU 160 229 229 GLU GLU F . n 
E 2 161 SER 161 230 230 SER SER F . n 
E 2 162 GLU 162 231 231 GLU GLU F . n 
E 2 163 GLY 163 232 232 GLY GLY F . n 
E 2 164 TRP 164 233 233 TRP TRP F . n 
E 2 165 ASN 165 234 234 ASN ASN F . n 
E 2 166 ARG 166 235 235 ARG ARG F . n 
E 2 167 ARG 167 236 236 ARG ARG F . n 
E 2 168 ASN 168 237 237 ASN ASN F . n 
E 2 169 VAL 169 238 238 VAL VAL F . n 
E 2 170 ASP 170 239 239 ASP ASP F . n 
E 2 171 PRO 171 240 240 PRO PRO F . n 
E 2 172 PHE 172 241 241 PHE PHE F . n 
E 2 173 HIS 173 242 242 HIS HIS F . n 
E 2 174 ILE 174 243 243 ILE ILE F . n 
E 2 175 TYR 175 244 244 TYR TYR F . n 
E 2 176 PHE 176 245 245 PHE PHE F . n 
E 2 177 CYS 177 246 246 CYS CYS F . n 
E 2 178 ASN 178 247 247 ASN ASN F . n 
E 2 179 LEU 179 248 248 LEU LEU F . n 
E 2 180 LYS 180 249 249 LYS LYS F . n 
E 2 181 ILE 181 250 250 ILE ILE F . n 
E 2 182 ASP 182 251 251 ASP ASP F . n 
E 2 183 GLY 183 252 252 GLY GLY F . n 
E 2 184 ALA 184 253 253 ALA ALA F . n 
E 2 185 LEU 185 254 254 LEU LEU F . n 
E 2 186 HIS 186 255 255 HIS HIS F . n 
E 2 187 ARG 187 256 256 ARG ARG F . n 
E 2 188 GLU 188 257 257 GLU GLU F . n 
E 2 189 LEU 189 258 258 LEU LEU F . n 
E 2 190 VAL 190 259 259 VAL VAL F . n 
E 2 191 LYS 191 260 260 LYS LYS F . n 
E 2 192 ARG 192 261 261 ARG ARG F . n 
E 2 193 TYR 193 262 262 TYR TYR F . n 
E 2 194 GLN 194 263 263 GLN GLN F . n 
E 2 195 GLU 195 264 264 GLU GLU F . n 
E 2 196 LYS 196 265 265 LYS LYS F . n 
E 2 197 TRP 197 266 266 TRP TRP F . n 
E 2 198 ASP 198 267 267 ASP ASP F . n 
E 2 199 LYS 199 268 268 LYS LYS F . n 
E 2 200 LEU 200 269 269 LEU LEU F . n 
E 2 201 LEU 201 270 270 LEU LEU F . n 
E 2 202 LEU 202 271 271 LEU LEU F . n 
E 2 203 THR 203 272 272 THR THR F . n 
E 2 204 SER 204 273 273 SER SER F . n 
E 2 205 THR 205 274 274 THR THR F . n 
E 2 206 GLU 206 275 275 GLU GLU F . n 
E 2 207 LYS 207 276 276 LYS LYS F . n 
E 2 208 SER 208 277 277 SER SER F . n 
E 2 209 HIS 209 278 278 HIS HIS F . n 
E 2 210 VAL 210 279 279 VAL VAL F . n 
E 2 211 ASP 211 280 280 ASP ASP F . n 
E 2 212 LEU 212 281 281 LEU LEU F . n 
E 2 213 PHE 213 282 282 PHE PHE F . n 
E 2 214 PRO 214 283 283 PRO PRO F . n 
E 2 215 LYS 215 284 284 LYS LYS F . n 
E 2 216 ASP 216 285 285 ASP ASP F . n 
E 2 217 SER 217 286 286 SER SER F . n 
E 2 218 ILE 218 287 287 ILE ILE F . n 
E 2 219 ILE 219 288 288 ILE ILE F . n 
E 2 220 TYR 220 289 289 TYR TYR F . n 
E 2 221 LEU 221 290 290 LEU LEU F . n 
E 2 222 THR 222 291 291 THR THR F . n 
E 2 223 ALA 223 292 292 ALA ALA F . n 
E 2 224 ASP 224 293 293 ASP ASP F . n 
E 2 225 SER 225 294 294 SER SER F . n 
E 2 226 PRO 226 295 295 PRO PRO F . n 
E 2 227 ASN 227 296 296 ASN ASN F . n 
E 2 228 VAL 228 297 297 VAL VAL F . n 
E 2 229 MET 229 298 298 MET MET F . n 
E 2 230 THR 230 299 299 THR THR F . n 
E 2 231 THR 231 300 300 THR THR F . n 
E 2 232 PHE 232 301 301 PHE PHE F . n 
E 2 233 ARG 233 302 302 ARG ARG F . n 
E 2 234 HIS 234 303 303 HIS HIS F . n 
E 2 235 ASP 235 304 304 ASP ASP F . n 
E 2 236 LYS 236 305 305 LYS LYS F . n 
E 2 237 VAL 237 306 306 VAL VAL F . n 
E 2 238 TYR 238 307 307 TYR TYR F . n 
E 2 239 VAL 239 308 308 VAL VAL F . n 
E 2 240 ILE 240 309 309 ILE ILE F . n 
E 2 241 GLY 241 310 310 GLY GLY F . n 
E 2 242 SER 242 311 311 SER SER F . n 
E 2 243 PHE 243 312 312 PHE PHE F . n 
E 2 244 VAL 244 313 313 VAL VAL F . n 
E 2 245 ASP 245 314 314 ASP ASP F . n 
E 2 246 LYS 246 315 315 LYS LYS F . n 
E 2 247 SER 247 316 316 SER SER F . n 
E 2 248 MET 248 317 317 MET MET F . n 
E 2 249 GLN 249 318 318 GLN GLN F . n 
E 2 250 PRO 250 319 319 PRO PRO F . n 
E 2 251 GLY 251 320 320 GLY GLY F . n 
E 2 252 THR 252 321 321 THR THR F . n 
E 2 253 SER 253 322 322 SER SER F . n 
E 2 254 LEU 254 323 323 LEU LEU F . n 
E 2 255 ALA 255 324 324 ALA ALA F . n 
E 2 256 LYS 256 325 325 LYS LYS F . n 
E 2 257 ALA 257 326 326 ALA ALA F . n 
E 2 258 LYS 258 327 327 LYS LYS F . n 
E 2 259 ARG 259 328 328 ARG ARG F . n 
E 2 260 LEU 260 329 329 LEU LEU F . n 
E 2 261 ASN 261 330 330 ASN ASN F . n 
E 2 262 LEU 262 331 331 LEU LEU F . n 
E 2 263 ALA 263 332 332 ALA ALA F . n 
E 2 264 THR 264 333 333 THR THR F . n 
E 2 265 GLU 265 334 334 GLU GLU F . n 
E 2 266 CYS 266 335 335 CYS CYS F . n 
E 2 267 LEU 267 336 336 LEU LEU F . n 
E 2 268 PRO 268 337 337 PRO PRO F . n 
E 2 269 LEU 269 338 338 LEU LEU F . n 
E 2 270 ASP 270 339 339 ASP ASP F . n 
E 2 271 LYS 271 340 340 LYS LYS F . n 
E 2 272 TYR 272 341 341 TYR TYR F . n 
E 2 273 LEU 273 342 342 LEU LEU F . n 
E 2 274 GLN 274 343 343 GLN GLN F . n 
E 2 275 TRP 275 344 344 TRP TRP F . n 
E 2 276 GLU 276 345 345 GLU GLU F . n 
E 2 277 ILE 277 346 346 ILE ILE F . n 
E 2 278 GLY 278 347 347 GLY GLY F . n 
E 2 279 ASN 279 348 348 ASN ASN F . n 
E 2 280 LYS 280 349 349 LYS LYS F . n 
E 2 281 ASN 281 350 350 ASN ASN F . n 
E 2 282 LEU 282 351 351 LEU LEU F . n 
E 2 283 THR 283 352 352 THR THR F . n 
E 2 284 LEU 284 353 353 LEU LEU F . n 
E 2 285 ASP 285 354 354 ASP ASP F . n 
E 2 286 GLN 286 355 355 GLN GLN F . n 
E 2 287 MET 287 356 356 MET MET F . n 
E 2 288 ILE 288 357 357 ILE ILE F . n 
E 2 289 ARG 289 358 358 ARG ARG F . n 
E 2 290 ILE 290 359 359 ILE ILE F . n 
E 2 291 LEU 291 360 360 LEU LEU F . n 
E 2 292 LEU 292 361 361 LEU LEU F . n 
E 2 293 CYS 293 362 362 CYS CYS F . n 
E 2 294 LEU 294 363 363 LEU LEU F . n 
E 2 295 LYS 295 364 364 LYS LYS F . n 
E 2 296 ASN 296 365 365 ASN ASN F . n 
E 2 297 ASN 297 366 366 ASN ASN F . n 
E 2 298 GLY 298 367 367 GLY GLY F . n 
E 2 299 ASN 299 368 368 ASN ASN F . n 
E 2 300 TRP 300 369 369 TRP TRP F . n 
E 2 301 GLN 301 370 370 GLN GLN F . n 
E 2 302 GLU 302 371 371 GLU GLU F . n 
E 2 303 ALA 303 372 372 ALA ALA F . n 
E 2 304 LEU 304 373 373 LEU LEU F . n 
E 2 305 GLN 305 374 374 GLN GLN F . n 
E 2 306 PHE 306 375 375 PHE PHE F . n 
E 2 307 VAL 307 376 376 VAL VAL F . n 
E 2 308 PRO 308 377 377 PRO PRO F . n 
E 2 309 LYS 309 378 378 LYS LYS F . n 
E 2 310 ARG 310 379 379 ARG ARG F . n 
E 2 311 LYS 311 380 380 LYS LYS F . n 
E 2 312 HIS 312 381 381 HIS HIS F . n 
E 2 313 THR 313 382 382 THR THR F . n 
E 2 314 GLY 314 383 383 GLY GLY F . n 
E 2 315 PHE 315 384 384 PHE PHE F . n 
E 2 316 LEU 316 385 385 LEU LEU F . n 
E 2 317 GLU 317 386 ?   ?   ?   F . n 
E 2 318 ILE 318 387 ?   ?   ?   F . n 
E 2 319 SER 319 388 ?   ?   ?   F . n 
E 2 320 GLN 320 389 ?   ?   ?   F . n 
E 2 321 HIS 321 390 ?   ?   ?   F . n 
E 2 322 SER 322 391 ?   ?   ?   F . n 
E 2 323 GLN 323 392 ?   ?   ?   F . n 
E 2 324 GLU 324 393 ?   ?   ?   F . n 
E 2 325 PHE 325 394 ?   ?   ?   F . n 
E 2 326 ILE 326 395 ?   ?   ?   F . n 
E 2 327 ASN 327 396 ?   ?   ?   F . n 
E 2 328 ARG 328 397 ?   ?   ?   F . n 
E 2 329 LEU 329 398 ?   ?   ?   F . n 
E 2 330 LYS 330 399 ?   ?   ?   F . n 
E 2 331 LYS 331 400 ?   ?   ?   F . n 
E 2 332 ALA 332 401 ?   ?   ?   F . n 
E 2 333 LYS 333 402 ?   ?   ?   F . n 
E 2 334 THR 334 403 ?   ?   ?   F . n 
E 2 335 ALA 335 404 ?   ?   ?   F . n 
E 2 336 GLU 336 405 ?   ?   ?   F . n 
E 2 337 ASN 337 406 ?   ?   ?   F . n 
E 2 338 LEU 338 407 ?   ?   ?   F . n 
E 2 339 TYR 339 408 ?   ?   ?   F . n 
E 2 340 PHE 340 409 ?   ?   ?   F . n 
E 2 341 GLN 341 410 ?   ?   ?   F . n 
E 2 342 SER 342 411 ?   ?   ?   F . n 
E 2 343 HIS 343 412 ?   ?   ?   F . n 
E 2 344 HIS 344 413 ?   ?   ?   F . n 
E 2 345 HIS 345 414 ?   ?   ?   F . n 
E 2 346 HIS 346 415 ?   ?   ?   F . n 
E 2 347 HIS 347 416 ?   ?   ?   F . n 
E 2 348 HIS 348 417 ?   ?   ?   F . n 
E 2 349 ASP 349 418 ?   ?   ?   F . n 
E 2 350 TYR 350 419 ?   ?   ?   F . n 
E 2 351 LYS 351 420 ?   ?   ?   F . n 
E 2 352 ASP 352 421 ?   ?   ?   F . n 
E 2 353 ASP 353 422 ?   ?   ?   F . n 
E 2 354 ASP 354 423 ?   ?   ?   F . n 
E 2 355 ASP 355 424 ?   ?   ?   F . n 
E 2 356 LYS 356 425 ?   ?   ?   F . n 
F 3 1   U   1   2   2   U   U   T . n 
F 3 2   A   2   3   3   A   A   T . n 
F 3 3   A   3   4   4   A   A   T . n 
F 3 4   A   4   5   5   A   A   T . n 
F 3 5   U   5   6   6   U   U   T . n 
F 3 6   A   6   7   7   A   A   T . n 
F 3 7   U   7   8   8   U   U   T . n 
F 3 8   A   8   9   9   A   A   T . n 
F 3 9   G   9   10  10  G   G   T . n 
F 3 10  U   10  11  11  U   U   T . n 
F 3 11  U   11  12  12  U   U   T . n 
F 3 12  U   12  13  13  U   U   T . n 
F 3 13  A   13  14  14  A   A   T . n 
F 3 14  A   14  15  15  A   A   T . n 
F 3 15  C   15  16  ?   ?   ?   T . n 
F 3 16  C   16  17  ?   ?   ?   T . n 
F 3 17  A   17  18  ?   ?   ?   T . n 
F 3 18  A   18  19  19  A   A   T . n 
F 3 19  A   19  20  20  A   A   T . n 
F 3 20  A   20  21  21  A   A   T . n 
F 3 21  C   21  22  22  C   C   T . n 
F 3 22  A   22  23  23  A   A   T . n 
F 3 23  U   23  24  24  U   U   T . n 
F 3 24  C   24  25  25  C   C   T . n 
F 3 25  A   25  26  26  A   A   T . n 
F 3 26  G   26  27  27  G   G   T . n 
F 3 27  A   27  28  28  A   A   T . n 
F 3 28  U   28  29  29  U   U   T . n 
F 3 29  U   29  30  30  U   U   T . n 
F 3 30  G   30  31  31  G   G   T . n 
F 3 31  U   31  32  32  U   U   T . n 
F 3 32  G   32  33  33  G   G   T . n 
F 3 33  A   33  34  34  A   A   T . n 
F 3 34  A   34  35  35  A   A   T . n 
F 3 35  U   35  36  36  U   U   T . n 
F 3 36  C   36  37  37  C   C   T . n 
F 3 37  U   37  38  38  U   U   T . n 
F 3 38  G   38  39  39  G   G   T . n 
F 3 39  A   39  40  40  A   A   T . n 
F 3 40  C   40  41  41  C   C   T . n 
F 3 41  A   41  42  42  A   A   T . n 
F 3 42  A   42  43  43  A   A   T . n 
F 3 43  C   43  44  44  C   C   T . n 
F 3 44  A   44  45  45  A   A   T . n 
F 3 45  G   45  46  46  G   G   T . n 
F 3 46  A   46  47  47  A   A   T . n 
F 3 47  G   47  48  48  G   G   T . n 
F 3 48  G   48  49  49  G   G   T . n 
F 3 49  C   49  50  50  C   C   T . n 
F 3 50  U   50  51  51  U   U   T . n 
F 3 51  U   51  52  52  U   U   T . n 
F 3 52  A   52  53  53  A   A   T . n 
F 3 53  C   53  54  54  C   C   T . n 
F 3 54  G   54  55  55  G   G   T . n 
F 3 55  A   55  56  56  A   A   T . n 
F 3 56  C   56  57  57  C   C   T . n 
F 3 57  C   57  58  58  C   C   T . n 
F 3 58  C   58  59  59  C   C   T . n 
F 3 59  C   59  60  60  C   C   T . n 
F 3 60  U   60  61  61  U   U   T . n 
F 3 61  U   61  62  62  U   U   T . n 
F 3 62  A   62  63  63  A   A   T . n 
F 3 63  U   63  64  64  U   U   T . n 
F 3 64  U   64  65  65  U   U   T . n 
F 3 65  U   65  66  66  U   U   T . n 
F 3 66  A   66  67  67  A   A   T . n 
F 3 67  C   67  68  68  C   C   T . n 
F 3 68  C   68  69  69  C   C   T . n 
F 3 69  C   69  70  70  C   C   T . n 
F 3 70  C   70  71  71  C   C   T . n 
F 3 71  A   71  72  ?   ?   ?   T . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        SAM 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   SAM 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 4 SAM 1 501 401 SAM SAM F . 
H 5 GTP 1 101 1   GTP GTP T . 
I 6 MG  1 102 1   MG  MG  T . 
J 7 HOH 1 601 4   HOH HOH F . 
J 7 HOH 2 602 1   HOH HOH F . 
J 7 HOH 3 603 3   HOH HOH F . 
J 7 HOH 4 604 6   HOH HOH F . 
J 7 HOH 5 605 10  HOH HOH F . 
J 7 HOH 6 606 2   HOH HOH F . 
J 7 HOH 7 607 7   HOH HOH F . 
J 7 HOH 8 608 5   HOH HOH F . 
K 7 HOH 1 201 8   HOH HOH T . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GCH 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GCH 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GCH 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               36.504 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.801 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9GCH 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.9 
_refine.ls_d_res_low                             1.9 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     859668 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    100.00 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.38577 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.38577 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'PARAMETERS FOR MASK CACLULATION' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD WITH PHASES' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.072 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             3.126 
_refine.overall_SU_ML                            0.082 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       . 
_refine_hist.d_res_low                        . 
_refine_hist.number_atoms_solvent             ? 
_refine_hist.number_atoms_total               11231 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        ? 
_refine_hist.pdbx_number_atoms_nucleic_acid   ? 
_refine_hist.pdbx_number_atoms_ligand         ? 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.015  0.012  11579 ? r_bond_refined_d             ? ? 
'ELECTRON MICROSCOPY' ? 0.000  0.016  10512 ? r_bond_other_d               ? ? 
'ELECTRON MICROSCOPY' ? 1.115  1.822  15952 ? r_angle_refined_deg          ? ? 
'ELECTRON MICROSCOPY' ? 0.374  1.739  24239 ? r_angle_other_deg            ? ? 
'ELECTRON MICROSCOPY' ? 4.722  6.084  1638  ? r_dihedral_angle_1_deg       ? ? 
'ELECTRON MICROSCOPY' ? 3.184  5.000  56    ? r_dihedral_angle_2_deg       ? ? 
'ELECTRON MICROSCOPY' ? 12.452 10.000 1705  ? r_dihedral_angle_3_deg       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'ELECTRON MICROSCOPY' ? 0.062  0.202  1913  ? r_chiral_restr               ? ? 
'ELECTRON MICROSCOPY' ? 0.004  0.020  12529 ? r_gen_planes_refined         ? ? 
'ELECTRON MICROSCOPY' ? 0.001  0.020  2425  ? r_gen_planes_other           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'ELECTRON MICROSCOPY' ? 1.985  2.866  5213  ? r_mcbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 1.985  2.866  5213  ? r_mcbond_other               ? ? 
'ELECTRON MICROSCOPY' ? 3.442  5.138  6504  ? r_mcangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 3.442  5.139  6505  ? r_mcangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 3.195  4.614  6366  ? r_scbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 3.195  4.622  6367  ? r_scbond_other               ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 5.615  8.346  9449  ? r_scangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 11.829 48.11  52704 ? r_long_range_B_refined       ? ? 
'ELECTRON MICROSCOPY' ? 11.829 48.12  52697 ? r_long_range_B_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_ls_shell.d_res_high                       1.600 
_refine_ls_shell.d_res_low                        1.642 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             0 
_refine_ls_shell.number_reflns_R_work             63630 
_refine_ls_shell.percent_reflns_obs               100.00 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.598 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.000 
# 
_struct.entry_id                     9GCH 
_struct.title                        'Human mitochondrial RNase Z with tRNA-His-CCA, SDR5C1/TRMT10C focus' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GCH 
_struct_keywords.text            'RNAseZ, ELAC2, mitochondria, tRNA, RNA BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'RNA BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 4 ? 
H N N 5 ? 
I N N 6 ? 
J N N 7 ? 
K N N 7 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP HCD2_HUMAN  Q99714     ? 1 
;MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKG
KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE
GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI
IENPFLNGEVIRLDGAIRMQP
;
1  
2 UNP TM10C_HUMAN Q7L0Y3     ? 2 
;MKSSVQEECVSTISSSKDEDPLAATREFIEMWRLLGREVPEHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIK
KEMKAAAREEAKNIKLLETTEEDKQKNFLFLRLWDRNMDIAMGWKGAQAMQFGQPLVFDMAYENYMKRKELQNTVSQLLE
SEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHVDLFPKDSIIYLTADSPNVMTTFRHDKVYVI
GSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGNKNLTLDQMIRILLCLKNNGNWQEALQFVPKRKHTGFLEISQ
HSQEFINRLKKAKT
;
70 
3 GB  LC530717.1  1896813685 ? 3 UAAAUAUAGUUUAACCAAAACAUCAGAUUGUGAAUCUGACAACAGAGGCUUACGACCCCUUAUUUACCCCA 3  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9GCH A 1 ? 261 ? Q99714     1  ? 261 ? 1  261 
2 1 9GCH B 1 ? 261 ? Q99714     1  ? 261 ? 1  261 
3 1 9GCH C 1 ? 261 ? Q99714     1  ? 261 ? 1  261 
4 1 9GCH D 1 ? 261 ? Q99714     1  ? 261 ? 1  261 
5 2 9GCH F 1 ? 334 ? Q7L0Y3     70 ? 403 ? 70 403 
6 3 9GCH T 1 ? 71  ? 1896813685 3  ? 73  ? 2  72  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
5 9GCH ALA F 335 ? UNP Q7L0Y3 ? ? 'expression tag' 404 1  
5 9GCH GLU F 336 ? UNP Q7L0Y3 ? ? 'expression tag' 405 2  
5 9GCH ASN F 337 ? UNP Q7L0Y3 ? ? 'expression tag' 406 3  
5 9GCH LEU F 338 ? UNP Q7L0Y3 ? ? 'expression tag' 407 4  
5 9GCH TYR F 339 ? UNP Q7L0Y3 ? ? 'expression tag' 408 5  
5 9GCH PHE F 340 ? UNP Q7L0Y3 ? ? 'expression tag' 409 6  
5 9GCH GLN F 341 ? UNP Q7L0Y3 ? ? 'expression tag' 410 7  
5 9GCH SER F 342 ? UNP Q7L0Y3 ? ? 'expression tag' 411 8  
5 9GCH HIS F 343 ? UNP Q7L0Y3 ? ? 'expression tag' 412 9  
5 9GCH HIS F 344 ? UNP Q7L0Y3 ? ? 'expression tag' 413 10 
5 9GCH HIS F 345 ? UNP Q7L0Y3 ? ? 'expression tag' 414 11 
5 9GCH HIS F 346 ? UNP Q7L0Y3 ? ? 'expression tag' 415 12 
5 9GCH HIS F 347 ? UNP Q7L0Y3 ? ? 'expression tag' 416 13 
5 9GCH HIS F 348 ? UNP Q7L0Y3 ? ? 'expression tag' 417 14 
5 9GCH ASP F 349 ? UNP Q7L0Y3 ? ? 'expression tag' 418 15 
5 9GCH TYR F 350 ? UNP Q7L0Y3 ? ? 'expression tag' 419 16 
5 9GCH LYS F 351 ? UNP Q7L0Y3 ? ? 'expression tag' 420 17 
5 9GCH ASP F 352 ? UNP Q7L0Y3 ? ? 'expression tag' 421 18 
5 9GCH ASP F 353 ? UNP Q7L0Y3 ? ? 'expression tag' 422 19 
5 9GCH ASP F 354 ? UNP Q7L0Y3 ? ? 'expression tag' 423 20 
5 9GCH ASP F 355 ? UNP Q7L0Y3 ? ? 'expression tag' 424 21 
5 9GCH LYS F 356 ? UNP Q7L0Y3 ? ? 'expression tag' 425 22 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 20  ? GLN A 33  ? SER A 20  GLN A 33  1 ? 14 
HELX_P HELX_P2  AA2 GLY A 46  ? GLY A 55  ? GLY A 46  GLY A 55  1 ? 10 
HELX_P HELX_P3  AA3 SER A 67  ? GLY A 83  ? SER A 67  GLY A 83  1 ? 17 
HELX_P HELX_P4  AA4 THR A 110 ? LEU A 122 ? THR A 110 LEU A 122 1 ? 13 
HELX_P HELX_P5  AA5 LEU A 122 ? GLN A 138 ? LEU A 122 GLN A 138 1 ? 17 
HELX_P HELX_P6  AA6 SER A 155 ? PHE A 159 ? SER A 155 PHE A 159 5 ? 5  
HELX_P HELX_P7  AA7 GLN A 165 ? ALA A 187 ? GLN A 165 ALA A 187 1 ? 23 
HELX_P HELX_P8  AA8 THR A 203 ? SER A 208 ? THR A 203 SER A 208 1 ? 6  
HELX_P HELX_P9  AA9 PRO A 210 ? GLN A 220 ? PRO A 210 GLN A 220 1 ? 11 
HELX_P HELX_P10 AB1 ASP A 229 ? ASN A 243 ? ASP A 229 ASN A 243 1 ? 15 
HELX_P HELX_P11 AB2 SER B 20  ? GLN B 33  ? SER B 20  GLN B 33  1 ? 14 
HELX_P HELX_P12 AB3 GLY B 46  ? GLY B 55  ? GLY B 46  GLY B 55  1 ? 10 
HELX_P HELX_P13 AB4 SER B 67  ? GLY B 83  ? SER B 67  GLY B 83  1 ? 17 
HELX_P HELX_P14 AB5 THR B 110 ? LEU B 122 ? THR B 110 LEU B 122 1 ? 13 
HELX_P HELX_P15 AB6 LEU B 122 ? GLN B 138 ? LEU B 122 GLN B 138 1 ? 17 
HELX_P HELX_P16 AB7 VAL B 156 ? GLY B 161 ? VAL B 156 GLY B 161 1 ? 6  
HELX_P HELX_P17 AB8 GLN B 165 ? ALA B 187 ? GLN B 165 ALA B 187 1 ? 23 
HELX_P HELX_P18 AB9 THR B 203 ? SER B 208 ? THR B 203 SER B 208 1 ? 6  
HELX_P HELX_P19 AC1 PRO B 210 ? VAL B 221 ? PRO B 210 VAL B 221 1 ? 12 
HELX_P HELX_P20 AC2 ASP B 229 ? ASN B 243 ? ASP B 229 ASN B 243 1 ? 15 
HELX_P HELX_P21 AC3 SER C 20  ? GLN C 33  ? SER C 20  GLN C 33  1 ? 14 
HELX_P HELX_P22 AC4 GLY C 46  ? GLY C 55  ? GLY C 46  GLY C 55  1 ? 10 
HELX_P HELX_P23 AC5 SER C 67  ? GLY C 83  ? SER C 67  GLY C 83  1 ? 17 
HELX_P HELX_P24 AC6 THR C 110 ? LEU C 122 ? THR C 110 LEU C 122 1 ? 13 
HELX_P HELX_P25 AC7 LEU C 122 ? GLN C 138 ? LEU C 122 GLN C 138 1 ? 17 
HELX_P HELX_P26 AC8 SER C 155 ? PHE C 159 ? SER C 155 PHE C 159 5 ? 5  
HELX_P HELX_P27 AC9 GLN C 165 ? ALA C 187 ? GLN C 165 ALA C 187 1 ? 23 
HELX_P HELX_P28 AD1 THR C 203 ? SER C 208 ? THR C 203 SER C 208 1 ? 6  
HELX_P HELX_P29 AD2 PRO C 210 ? VAL C 221 ? PRO C 210 VAL C 221 1 ? 12 
HELX_P HELX_P30 AD3 ASP C 229 ? ASN C 243 ? ASP C 229 ASN C 243 1 ? 15 
HELX_P HELX_P31 AD4 SER D 20  ? GLN D 33  ? SER D 20  GLN D 33  1 ? 14 
HELX_P HELX_P32 AD5 GLY D 46  ? GLY D 55  ? GLY D 46  GLY D 55  1 ? 10 
HELX_P HELX_P33 AD6 SER D 67  ? GLY D 83  ? SER D 67  GLY D 83  1 ? 17 
HELX_P HELX_P34 AD7 THR D 110 ? LEU D 122 ? THR D 110 LEU D 122 1 ? 13 
HELX_P HELX_P35 AD8 LEU D 122 ? GLN D 138 ? LEU D 122 GLN D 138 1 ? 17 
HELX_P HELX_P36 AD9 SER D 155 ? PHE D 159 ? SER D 155 PHE D 159 5 ? 5  
HELX_P HELX_P37 AE1 GLN D 165 ? ALA D 187 ? GLN D 165 ALA D 187 1 ? 23 
HELX_P HELX_P38 AE2 THR D 203 ? SER D 208 ? THR D 203 SER D 208 1 ? 6  
HELX_P HELX_P39 AE3 PRO D 210 ? VAL D 221 ? PRO D 210 VAL D 221 1 ? 12 
HELX_P HELX_P40 AE4 ASP D 229 ? ASN D 243 ? ASP D 229 ASN D 243 1 ? 15 
HELX_P HELX_P41 AE5 ALA E 24  ? LEU E 35  ? ALA F 93  LEU F 104 1 ? 12 
HELX_P HELX_P42 AE6 THR E 44  ? CYS E 54  ? THR F 113 CYS F 123 1 ? 11 
HELX_P HELX_P43 AE7 SER E 56  ? LYS E 95  ? SER F 125 LYS F 164 1 ? 40 
HELX_P HELX_P44 AE8 LEU E 113 ? GLY E 133 ? LEU F 182 GLY F 202 1 ? 21 
HELX_P HELX_P45 AE9 TYR E 142 ? MET E 146 ? TYR F 211 MET F 215 5 ? 5  
HELX_P HELX_P46 AF1 LYS E 147 ? ASN E 168 ? LYS F 216 ASN F 237 1 ? 22 
HELX_P HELX_P47 AF2 GLY E 183 ? GLN E 194 ? GLY F 252 GLN F 263 1 ? 12 
HELX_P HELX_P48 AF3 GLU E 195 ? LEU E 200 ? GLU F 264 LEU F 269 5 ? 6  
HELX_P HELX_P49 AF4 SER E 208 ? LEU E 212 ? SER F 277 LEU F 281 5 ? 5  
HELX_P HELX_P50 AF5 PRO E 214 ? ASP E 216 ? PRO F 283 ASP F 285 5 ? 3  
HELX_P HELX_P51 AF6 GLY E 251 ? LEU E 260 ? GLY F 320 LEU F 329 1 ? 10 
HELX_P HELX_P52 AF7 PRO E 268 ? TYR E 272 ? PRO F 337 TYR F 341 1 ? 5  
HELX_P HELX_P53 AF8 THR E 283 ? ASN E 296 ? THR F 352 ASN F 365 1 ? 14 
HELX_P HELX_P54 AF9 ASN E 299 ? LEU E 304 ? ASN F 368 LEU F 373 1 ? 6  
HELX_P HELX_P55 AG1 GLN E 305 ? VAL E 307 ? GLN F 374 VAL F 376 5 ? 3  
HELX_P HELX_P56 AG2 PRO E 308 ? ARG E 310 ? PRO F 377 ARG F 379 5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale both ? F U   1  P   ? ? ? 1_555 H GTP .  "O3'" ? ? T U   2   T GTP 101 1_555 ? ? ? ? ? ? ?             1.619 ? ? 
metalc1  metalc ?    ? J HOH .  O   ? ? ? 1_555 I MG  .  MG    ? ? F HOH 607 T MG  102 1_555 ? ? ? ? ? ? ?             2.682 ? ? 
metalc2  metalc ?    ? F U   10 OP1 ? ? ? 1_555 I MG  .  MG    ? ? T U   11  T MG  102 1_555 ? ? ? ? ? ? ?             2.021 ? ? 
hydrog1  hydrog ?    ? F U   1  N3  ? ? ? 1_555 F A   66 N1    ? ? T U   2   T A   67  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog2  hydrog ?    ? F U   1  O4  ? ? ? 1_555 F A   66 N6    ? ? T U   2   T A   67  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog3  hydrog ?    ? F A   2  N1  ? ? ? 1_555 F U   65 N3    ? ? T A   3   T U   66  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog4  hydrog ?    ? F A   2  N6  ? ? ? 1_555 F U   65 O4    ? ? T A   3   T U   66  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog5  hydrog ?    ? F A   3  N1  ? ? ? 1_555 F U   64 N3    ? ? T A   4   T U   65  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog6  hydrog ?    ? F A   3  N6  ? ? ? 1_555 F U   64 O4    ? ? T A   4   T U   65  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog7  hydrog ?    ? F A   4  N1  ? ? ? 1_555 F U   63 N3    ? ? T A   5   T U   64  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog8  hydrog ?    ? F A   4  N6  ? ? ? 1_555 F U   63 O4    ? ? T A   5   T U   64  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog9  hydrog ?    ? F U   5  N3  ? ? ? 1_555 F A   62 N1    ? ? T U   6   T A   63  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog10 hydrog ?    ? F U   5  O4  ? ? ? 1_555 F A   62 N6    ? ? T U   6   T A   63  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog11 hydrog ?    ? F A   6  N1  ? ? ? 1_555 F U   61 N3    ? ? T A   7   T U   62  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog12 hydrog ?    ? F A   6  N6  ? ? ? 1_555 F U   61 O4    ? ? T A   7   T U   62  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog13 hydrog ?    ? F U   7  N3  ? ? ? 1_555 F U   12 O4    ? ? T U   8   T U   13  1_555 ? ? ? ? ? ? 'U-U MISPAIR' ?     ? ? 
hydrog14 hydrog ?    ? F G   9  N1  ? ? ? 1_555 F C   21 N3    ? ? T G   10  T C   22  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog15 hydrog ?    ? F G   9  N2  ? ? ? 1_555 F C   21 O2    ? ? T G   10  T C   22  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog16 hydrog ?    ? F G   9  O6  ? ? ? 1_555 F C   21 N4    ? ? T G   10  T C   22  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog17 hydrog ?    ? F U   10 N3  ? ? ? 1_555 F A   20 N1    ? ? T U   11  T A   21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog18 hydrog ?    ? F U   10 O4  ? ? ? 1_555 F A   20 N6    ? ? T U   11  T A   21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog19 hydrog ?    ? F U   11 N3  ? ? ? 1_555 F A   19 N1    ? ? T U   12  T A   20  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog20 hydrog ?    ? F U   11 O4  ? ? ? 1_555 F A   19 N6    ? ? T U   12  T A   20  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog21 hydrog ?    ? F U   12 N3  ? ? ? 1_555 F A   18 N1    ? ? T U   13  T A   19  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog22 hydrog ?    ? F U   12 O4  ? ? ? 1_555 F A   18 N6    ? ? T U   13  T A   19  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog23 hydrog ?    ? F A   13 N1  ? ? ? 1_555 F C   43 N4    ? ? T A   14  T C   44  1_555 ? ? ? ? ? ? 'A-C MISPAIR' ?     ? ? 
hydrog24 hydrog ?    ? F U   23 N3  ? ? ? 1_555 F A   39 N1    ? ? T U   24  T A   40  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog25 hydrog ?    ? F U   23 O4  ? ? ? 1_555 F A   39 N6    ? ? T U   24  T A   40  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog26 hydrog ?    ? F C   24 N3  ? ? ? 1_555 F G   38 N1    ? ? T C   25  T G   39  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog27 hydrog ?    ? F C   24 N4  ? ? ? 1_555 F G   38 O6    ? ? T C   25  T G   39  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog28 hydrog ?    ? F C   24 O2  ? ? ? 1_555 F G   38 N2    ? ? T C   25  T G   39  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog29 hydrog ?    ? F A   25 N1  ? ? ? 1_555 F U   37 N3    ? ? T A   26  T U   38  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog30 hydrog ?    ? F A   25 N6  ? ? ? 1_555 F U   37 O4    ? ? T A   26  T U   38  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog31 hydrog ?    ? F G   26 N1  ? ? ? 1_555 F C   36 N3    ? ? T G   27  T C   37  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog32 hydrog ?    ? F G   26 N2  ? ? ? 1_555 F C   36 O2    ? ? T G   27  T C   37  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog33 hydrog ?    ? F G   26 O6  ? ? ? 1_555 F C   36 N4    ? ? T G   27  T C   37  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog34 hydrog ?    ? F A   27 N1  ? ? ? 1_555 F U   35 N3    ? ? T A   28  T U   36  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog35 hydrog ?    ? F A   27 N6  ? ? ? 1_555 F U   35 O4    ? ? T A   28  T U   36  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog36 hydrog ?    ? F A   44 N1  ? ? ? 1_555 F U   60 N3    ? ? T A   45  T U   61  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog37 hydrog ?    ? F A   44 N6  ? ? ? 1_555 F U   60 O4    ? ? T A   45  T U   61  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog38 hydrog ?    ? F G   45 N1  ? ? ? 1_555 F C   59 N3    ? ? T G   46  T C   60  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog39 hydrog ?    ? F G   45 N2  ? ? ? 1_555 F C   59 O2    ? ? T G   46  T C   60  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog40 hydrog ?    ? F G   45 O6  ? ? ? 1_555 F C   59 N4    ? ? T G   46  T C   60  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog41 hydrog ?    ? F A   46 N6  ? ? ? 1_555 F C   58 N3    ? ? T A   47  T C   59  1_555 ? ? ? ? ? ? 'A-C MISPAIR' ?     ? ? 
hydrog42 hydrog ?    ? F G   47 N1  ? ? ? 1_555 F C   57 N3    ? ? T G   48  T C   58  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog43 hydrog ?    ? F G   47 N2  ? ? ? 1_555 F C   57 O2    ? ? T G   48  T C   58  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog44 hydrog ?    ? F G   47 O6  ? ? ? 1_555 F C   57 N4    ? ? T G   48  T C   58  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog45 hydrog ?    ? F G   48 N1  ? ? ? 1_555 F C   56 N3    ? ? T G   49  T C   57  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog46 hydrog ?    ? F G   48 N2  ? ? ? 1_555 F C   56 O2    ? ? T G   49  T C   57  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog47 hydrog ?    ? F G   48 O6  ? ? ? 1_555 F C   56 N4    ? ? T G   49  T C   57  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog48 hydrog ?    ? F C   49 N3  ? ? ? 1_555 F A   55 N6    ? ? T C   50  T A   56  1_555 ? ? ? ? ? ? 'C-A MISPAIR' ?     ? ? 
hydrog49 hydrog ?    ? F U   50 O2  ? ? ? 1_555 F C   53 N4    ? ? T U   51  T C   54  1_555 ? ? ? ? ? ? 'U-C MISPAIR' ?     ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
hydrog ? ? 
# 
_pdbx_struct_conn_angle.id                    1 
_pdbx_struct_conn_angle.ptnr1_label_atom_id   O 
_pdbx_struct_conn_angle.ptnr1_label_alt_id    ? 
_pdbx_struct_conn_angle.ptnr1_label_asym_id   J 
_pdbx_struct_conn_angle.ptnr1_label_comp_id   HOH 
_pdbx_struct_conn_angle.ptnr1_label_seq_id    . 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id    ? 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id    F 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id    HOH 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id     607 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code    ? 
_pdbx_struct_conn_angle.ptnr1_symmetry        1_555 
_pdbx_struct_conn_angle.ptnr2_label_atom_id   MG 
_pdbx_struct_conn_angle.ptnr2_label_alt_id    ? 
_pdbx_struct_conn_angle.ptnr2_label_asym_id   I 
_pdbx_struct_conn_angle.ptnr2_label_comp_id   MG 
_pdbx_struct_conn_angle.ptnr2_label_seq_id    . 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id    ? 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id    T 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id    MG 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id     102 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code    ? 
_pdbx_struct_conn_angle.ptnr2_symmetry        1_555 
_pdbx_struct_conn_angle.ptnr3_label_atom_id   OP1 
_pdbx_struct_conn_angle.ptnr3_label_alt_id    ? 
_pdbx_struct_conn_angle.ptnr3_label_asym_id   F 
_pdbx_struct_conn_angle.ptnr3_label_comp_id   U 
_pdbx_struct_conn_angle.ptnr3_label_seq_id    10 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id    ? 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id    T 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id    U 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id     11 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code    ? 
_pdbx_struct_conn_angle.ptnr3_symmetry        1_555 
_pdbx_struct_conn_angle.value                 117.9 
_pdbx_struct_conn_angle.value_esd             ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 223 A . ? PHE 223 A PRO 224 A ? PRO 224 A 1 -7.06 
2 PHE 223 B . ? PHE 223 B PRO 224 B ? PRO 224 B 1 -5.09 
3 PHE 223 C . ? PHE 223 C PRO 224 C ? PRO 224 C 1 -3.75 
4 PHE 223 D . ? PHE 223 D PRO 224 D ? PRO 224 D 1 -5.55 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 2 ? 
AA3 ? 7 ? 
AA4 ? 2 ? 
AA5 ? 7 ? 
AA6 ? 2 ? 
AA7 ? 7 ? 
AA8 ? 2 ? 
AA9 ? 6 ? 
AB1 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA3 6 7 ? parallel      
AA4 1 2 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? parallel      
AA5 3 4 ? parallel      
AA5 4 5 ? parallel      
AA5 5 6 ? parallel      
AA5 6 7 ? parallel      
AA6 1 2 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? parallel      
AA7 3 4 ? parallel      
AA7 4 5 ? parallel      
AA7 5 6 ? parallel      
AA7 6 7 ? parallel      
AA8 1 2 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? parallel      
AA9 3 4 ? parallel      
AA9 4 5 ? parallel      
AA9 5 6 ? parallel      
AB1 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 CYS A 58  ? PRO A 62  ? CYS A 58  PRO A 62  
AA1 2 SER A 36  ? ASP A 41  ? SER A 36  ASP A 41  
AA1 3 VAL A 12  ? THR A 16  ? VAL A 12  THR A 16  
AA1 4 VAL A 87  ? ASN A 90  ? VAL A 87  ASN A 90  
AA1 5 GLY A 148 ? THR A 153 ? GLY A 148 THR A 153 
AA1 6 ILE A 191 ? PRO A 198 ? ILE A 191 PRO A 198 
AA1 7 VAL A 250 ? LEU A 253 ? VAL A 250 LEU A 253 
AA2 1 TYR A 101 ? ASN A 102 ? TYR A 101 ASN A 102 
AA2 2 GLN A 107 ? THR A 108 ? GLN A 107 THR A 108 
AA3 1 CYS B 58  ? PRO B 62  ? CYS B 58  PRO B 62  
AA3 2 SER B 36  ? ASP B 41  ? SER B 36  ASP B 41  
AA3 3 VAL B 12  ? THR B 16  ? VAL B 12  THR B 16  
AA3 4 VAL B 87  ? ASN B 90  ? VAL B 87  ASN B 90  
AA3 5 GLY B 148 ? THR B 153 ? GLY B 148 THR B 153 
AA3 6 ILE B 191 ? PRO B 198 ? ILE B 191 PRO B 198 
AA3 7 VAL B 250 ? LEU B 253 ? VAL B 250 LEU B 253 
AA4 1 TYR B 101 ? ASN B 102 ? TYR B 101 ASN B 102 
AA4 2 GLN B 107 ? THR B 108 ? GLN B 107 THR B 108 
AA5 1 CYS C 58  ? PRO C 62  ? CYS C 58  PRO C 62  
AA5 2 SER C 36  ? ASP C 41  ? SER C 36  ASP C 41  
AA5 3 VAL C 12  ? THR C 16  ? VAL C 12  THR C 16  
AA5 4 VAL C 87  ? ASN C 90  ? VAL C 87  ASN C 90  
AA5 5 GLY C 148 ? THR C 153 ? GLY C 148 THR C 153 
AA5 6 ILE C 191 ? PRO C 198 ? ILE C 191 PRO C 198 
AA5 7 VAL C 250 ? LEU C 253 ? VAL C 250 LEU C 253 
AA6 1 TYR C 101 ? ASN C 102 ? TYR C 101 ASN C 102 
AA6 2 GLN C 107 ? THR C 108 ? GLN C 107 THR C 108 
AA7 1 CYS D 58  ? PRO D 62  ? CYS D 58  PRO D 62  
AA7 2 SER D 36  ? ASP D 41  ? SER D 36  ASP D 41  
AA7 3 VAL D 12  ? THR D 16  ? VAL D 12  THR D 16  
AA7 4 VAL D 87  ? ASN D 90  ? VAL D 87  ASN D 90  
AA7 5 GLY D 148 ? THR D 153 ? GLY D 148 THR D 153 
AA7 6 ILE D 191 ? PRO D 198 ? ILE D 191 PRO D 198 
AA7 7 VAL D 250 ? LEU D 253 ? VAL D 250 LEU D 253 
AA8 1 TYR D 101 ? ASN D 102 ? TYR D 101 ASN D 102 
AA8 2 GLN D 107 ? THR D 108 ? GLN D 107 THR D 108 
AA9 1 THR E 203 ? SER E 204 ? THR F 272 SER F 273 
AA9 2 HIS E 173 ? CYS E 177 ? HIS F 242 CYS F 246 
AA9 3 PRO E 135 ? ASP E 139 ? PRO F 204 ASP F 208 
AA9 4 VAL E 237 ? GLY E 241 ? VAL F 306 GLY F 310 
AA9 5 ILE E 218 ? LEU E 221 ? ILE F 287 LEU F 290 
AA9 6 ALA E 263 ? GLU E 265 ? ALA F 332 GLU F 334 
AB1 1 LEU E 273 ? TRP E 275 ? LEU F 342 TRP F 344 
AB1 2 HIS E 312 ? PHE E 315 ? HIS F 381 PHE F 384 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 61  ? O ALA A 61  N LEU A 39  ? N LEU A 39  
AA1 2 3 O SER A 36  ? O SER A 36  N ALA A 13  ? N ALA A 13  
AA1 3 4 N THR A 16  ? N THR A 16  O VAL A 89  ? O VAL A 89  
AA1 4 5 N ALA A 88  ? N ALA A 88  O ILE A 151 ? O ILE A 151 
AA1 5 6 N ILE A 150 ? N ILE A 150 O ARG A 192 ? O ARG A 192 
AA1 6 7 N ALA A 197 ? N ALA A 197 O ILE A 251 ? O ILE A 251 
AA2 1 2 N ASN A 102 ? N ASN A 102 O GLN A 107 ? O GLN A 107 
AA3 1 2 O ALA B 61  ? O ALA B 61  N LEU B 39  ? N LEU B 39  
AA3 2 3 O SER B 36  ? O SER B 36  N ALA B 13  ? N ALA B 13  
AA3 3 4 N VAL B 14  ? N VAL B 14  O VAL B 87  ? O VAL B 87  
AA3 4 5 N ALA B 88  ? N ALA B 88  O ILE B 151 ? O ILE B 151 
AA3 5 6 N ILE B 150 ? N ILE B 150 O ARG B 192 ? O ARG B 192 
AA3 6 7 N ALA B 197 ? N ALA B 197 O ILE B 251 ? O ILE B 251 
AA4 1 2 N ASN B 102 ? N ASN B 102 O GLN B 107 ? O GLN B 107 
AA5 1 2 O ALA C 61  ? O ALA C 61  N LEU C 39  ? N LEU C 39  
AA5 2 3 O SER C 36  ? O SER C 36  N ALA C 13  ? N ALA C 13  
AA5 3 4 N VAL C 14  ? N VAL C 14  O VAL C 87  ? O VAL C 87  
AA5 4 5 N ALA C 88  ? N ALA C 88  O ILE C 151 ? O ILE C 151 
AA5 5 6 N ILE C 150 ? N ILE C 150 O ARG C 192 ? O ARG C 192 
AA5 6 7 N ALA C 197 ? N ALA C 197 O ILE C 251 ? O ILE C 251 
AA6 1 2 N ASN C 102 ? N ASN C 102 O GLN C 107 ? O GLN C 107 
AA7 1 2 O ALA D 61  ? O ALA D 61  N LEU D 39  ? N LEU D 39  
AA7 2 3 O SER D 36  ? O SER D 36  N ALA D 13  ? N ALA D 13  
AA7 3 4 N THR D 16  ? N THR D 16  O VAL D 89  ? O VAL D 89  
AA7 4 5 N ALA D 88  ? N ALA D 88  O ILE D 151 ? O ILE D 151 
AA7 5 6 N ILE D 150 ? N ILE D 150 O ARG D 192 ? O ARG D 192 
AA7 6 7 N ALA D 197 ? N ALA D 197 O ILE D 251 ? O ILE D 251 
AA8 1 2 N ASN D 102 ? N ASN D 102 O GLN D 107 ? O GLN D 107 
AA9 1 2 O THR E 203 ? O THR F 272 N PHE E 176 ? N PHE F 245 
AA9 2 3 O TYR E 175 ? O TYR F 244 N LEU E 136 ? N LEU F 205 
AA9 3 4 N VAL E 137 ? N VAL F 206 O ILE E 240 ? O ILE F 309 
AA9 4 5 O VAL E 237 ? O VAL F 306 N ILE E 219 ? N ILE F 288 
AA9 5 6 N TYR E 220 ? N TYR F 289 O ALA E 263 ? O ALA F 332 
AB1 1 2 N GLN E 274 ? N GLN F 343 O GLY E 314 ? O GLY F 383 
# 
_pdbx_entry_details.entry_id                   9GCH 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA A 154 ? ? -88.87 -157.89 
2  1 ASP B 142 ? ? -77.39 -168.75 
3  1 ALA B 154 ? ? -89.66 -157.04 
4  1 ALA C 154 ? ? -89.92 -157.40 
5  1 ASP D 142 ? ? -77.94 -168.48 
6  1 ALA D 154 ? ? -88.77 -156.60 
7  1 LEU D 200 ? ? 56.14  74.28   
8  1 ARG F 106 ? ? -93.93 50.53   
9  1 MET F 209 ? ? -97.26 30.01   
10 1 GLN F 263 ? ? 61.90  -128.87 
11 1 ASN F 330 ? ? -69.42 81.73   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9GCH 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  7ONU 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                7ONU 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    9GCH 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  1.9 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               293773 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 'MULTIPLE SOURCES' COMPLEX 'RNAseZ with mt-tRNA-His' ? ? ? '1, 2, 3' 
2 1 RECOMBINANT        COMPLEX RNAseZ                    ? ? ? '1, 2'    
3 1 RECOMBINANT        COMPLEX mt-tRNA-His               ? ? ? 3         
# 
_em_imaging.entry_id                        9GCH 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             400 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9GCH 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9GCH 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ALA 2   ? A ALA 2   
3   1 Y 1 A ALA 3   ? A ALA 3   
4   1 Y 1 A ALA 4   ? A ALA 4   
5   1 Y 1 A CYS 5   ? A CYS 5   
6   1 Y 1 A ARG 6   ? A ARG 6   
7   1 Y 1 B MET 1   ? B MET 1   
8   1 Y 1 B ALA 2   ? B ALA 2   
9   1 Y 1 B ALA 3   ? B ALA 3   
10  1 Y 1 B ALA 4   ? B ALA 4   
11  1 Y 1 B CYS 5   ? B CYS 5   
12  1 Y 1 B ARG 6   ? B ARG 6   
13  1 Y 1 C MET 1   ? C MET 1   
14  1 Y 1 C ALA 2   ? C ALA 2   
15  1 Y 1 C ALA 3   ? C ALA 3   
16  1 Y 1 C ALA 4   ? C ALA 4   
17  1 Y 1 C CYS 5   ? C CYS 5   
18  1 Y 1 C ARG 6   ? C ARG 6   
19  1 Y 1 D MET 1   ? D MET 1   
20  1 Y 1 D ALA 2   ? D ALA 2   
21  1 Y 1 D ALA 3   ? D ALA 3   
22  1 Y 1 D ALA 4   ? D ALA 4   
23  1 Y 1 D CYS 5   ? D CYS 5   
24  1 Y 1 D ARG 6   ? D ARG 6   
25  1 Y 1 F MET 70  ? E MET 1   
26  1 Y 1 F LYS 71  ? E LYS 2   
27  1 Y 1 F SER 72  ? E SER 3   
28  1 Y 1 F SER 73  ? E SER 4   
29  1 Y 1 F VAL 74  ? E VAL 5   
30  1 Y 1 F GLN 75  ? E GLN 6   
31  1 Y 1 F GLU 76  ? E GLU 7   
32  1 Y 1 F GLU 77  ? E GLU 8   
33  1 Y 1 F CYS 78  ? E CYS 9   
34  1 Y 1 F VAL 79  ? E VAL 10  
35  1 Y 1 F SER 80  ? E SER 11  
36  1 Y 1 F THR 81  ? E THR 12  
37  1 Y 1 F ILE 82  ? E ILE 13  
38  1 Y 1 F SER 83  ? E SER 14  
39  1 Y 1 F SER 84  ? E SER 15  
40  1 Y 1 F SER 85  ? E SER 16  
41  1 Y 1 F LYS 86  ? E LYS 17  
42  1 Y 1 F ASP 87  ? E ASP 18  
43  1 Y 1 F GLU 88  ? E GLU 19  
44  1 Y 1 F ASP 89  ? E ASP 20  
45  1 Y 1 F PRO 90  ? E PRO 21  
46  1 Y 1 F LEU 91  ? E LEU 22  
47  1 Y 1 F LEU 165 ? E LEU 96  
48  1 Y 1 F LEU 166 ? E LEU 97  
49  1 Y 1 F GLU 167 ? E GLU 98  
50  1 Y 1 F THR 168 ? E THR 99  
51  1 Y 1 F THR 169 ? E THR 100 
52  1 Y 1 F GLU 170 ? E GLU 101 
53  1 Y 1 F GLU 171 ? E GLU 102 
54  1 Y 1 F ASP 172 ? E ASP 103 
55  1 Y 1 F LYS 173 ? E LYS 104 
56  1 Y 1 F GLN 174 ? E GLN 105 
57  1 Y 1 F GLU 386 ? E GLU 317 
58  1 Y 1 F ILE 387 ? E ILE 318 
59  1 Y 1 F SER 388 ? E SER 319 
60  1 Y 1 F GLN 389 ? E GLN 320 
61  1 Y 1 F HIS 390 ? E HIS 321 
62  1 Y 1 F SER 391 ? E SER 322 
63  1 Y 1 F GLN 392 ? E GLN 323 
64  1 Y 1 F GLU 393 ? E GLU 324 
65  1 Y 1 F PHE 394 ? E PHE 325 
66  1 Y 1 F ILE 395 ? E ILE 326 
67  1 Y 1 F ASN 396 ? E ASN 327 
68  1 Y 1 F ARG 397 ? E ARG 328 
69  1 Y 1 F LEU 398 ? E LEU 329 
70  1 Y 1 F LYS 399 ? E LYS 330 
71  1 Y 1 F LYS 400 ? E LYS 331 
72  1 Y 1 F ALA 401 ? E ALA 332 
73  1 Y 1 F LYS 402 ? E LYS 333 
74  1 Y 1 F THR 403 ? E THR 334 
75  1 Y 1 F ALA 404 ? E ALA 335 
76  1 Y 1 F GLU 405 ? E GLU 336 
77  1 Y 1 F ASN 406 ? E ASN 337 
78  1 Y 1 F LEU 407 ? E LEU 338 
79  1 Y 1 F TYR 408 ? E TYR 339 
80  1 Y 1 F PHE 409 ? E PHE 340 
81  1 Y 1 F GLN 410 ? E GLN 341 
82  1 Y 1 F SER 411 ? E SER 342 
83  1 Y 1 F HIS 412 ? E HIS 343 
84  1 Y 1 F HIS 413 ? E HIS 344 
85  1 Y 1 F HIS 414 ? E HIS 345 
86  1 Y 1 F HIS 415 ? E HIS 346 
87  1 Y 1 F HIS 416 ? E HIS 347 
88  1 Y 1 F HIS 417 ? E HIS 348 
89  1 Y 1 F ASP 418 ? E ASP 349 
90  1 Y 1 F TYR 419 ? E TYR 350 
91  1 Y 1 F LYS 420 ? E LYS 351 
92  1 Y 1 F ASP 421 ? E ASP 352 
93  1 Y 1 F ASP 422 ? E ASP 353 
94  1 Y 1 F ASP 423 ? E ASP 354 
95  1 Y 1 F ASP 424 ? E ASP 355 
96  1 Y 1 F LYS 425 ? E LYS 356 
97  1 Y 1 T C   16  ? F C   15  
98  1 Y 1 T C   17  ? F C   16  
99  1 Y 1 T A   18  ? F A   17  
100 1 Y 1 T A   72  ? F A   71  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A   OP3    O  N N 1   
A   P      P  N N 2   
A   OP1    O  N N 3   
A   OP2    O  N N 4   
A   "O5'"  O  N N 5   
A   "C5'"  C  N N 6   
A   "C4'"  C  N R 7   
A   "O4'"  O  N N 8   
A   "C3'"  C  N S 9   
A   "O3'"  O  N N 10  
A   "C2'"  C  N R 11  
A   "O2'"  O  N N 12  
A   "C1'"  C  N R 13  
A   N9     N  Y N 14  
A   C8     C  Y N 15  
A   N7     N  Y N 16  
A   C5     C  Y N 17  
A   C6     C  Y N 18  
A   N6     N  N N 19  
A   N1     N  Y N 20  
A   C2     C  Y N 21  
A   N3     N  Y N 22  
A   C4     C  Y N 23  
A   HOP3   H  N N 24  
A   HOP2   H  N N 25  
A   "H5'"  H  N N 26  
A   "H5''" H  N N 27  
A   "H4'"  H  N N 28  
A   "H3'"  H  N N 29  
A   "HO3'" H  N N 30  
A   "H2'"  H  N N 31  
A   "HO2'" H  N N 32  
A   "H1'"  H  N N 33  
A   H8     H  N N 34  
A   H61    H  N N 35  
A   H62    H  N N 36  
A   H2     H  N N 37  
ALA N      N  N N 38  
ALA CA     C  N S 39  
ALA C      C  N N 40  
ALA O      O  N N 41  
ALA CB     C  N N 42  
ALA OXT    O  N N 43  
ALA H      H  N N 44  
ALA H2     H  N N 45  
ALA HA     H  N N 46  
ALA HB1    H  N N 47  
ALA HB2    H  N N 48  
ALA HB3    H  N N 49  
ALA HXT    H  N N 50  
ARG N      N  N N 51  
ARG CA     C  N S 52  
ARG C      C  N N 53  
ARG O      O  N N 54  
ARG CB     C  N N 55  
ARG CG     C  N N 56  
ARG CD     C  N N 57  
ARG NE     N  N N 58  
ARG CZ     C  N N 59  
ARG NH1    N  N N 60  
ARG NH2    N  N N 61  
ARG OXT    O  N N 62  
ARG H      H  N N 63  
ARG H2     H  N N 64  
ARG HA     H  N N 65  
ARG HB2    H  N N 66  
ARG HB3    H  N N 67  
ARG HG2    H  N N 68  
ARG HG3    H  N N 69  
ARG HD2    H  N N 70  
ARG HD3    H  N N 71  
ARG HE     H  N N 72  
ARG HH11   H  N N 73  
ARG HH12   H  N N 74  
ARG HH21   H  N N 75  
ARG HH22   H  N N 76  
ARG HXT    H  N N 77  
ASN N      N  N N 78  
ASN CA     C  N S 79  
ASN C      C  N N 80  
ASN O      O  N N 81  
ASN CB     C  N N 82  
ASN CG     C  N N 83  
ASN OD1    O  N N 84  
ASN ND2    N  N N 85  
ASN OXT    O  N N 86  
ASN H      H  N N 87  
ASN H2     H  N N 88  
ASN HA     H  N N 89  
ASN HB2    H  N N 90  
ASN HB3    H  N N 91  
ASN HD21   H  N N 92  
ASN HD22   H  N N 93  
ASN HXT    H  N N 94  
ASP N      N  N N 95  
ASP CA     C  N S 96  
ASP C      C  N N 97  
ASP O      O  N N 98  
ASP CB     C  N N 99  
ASP CG     C  N N 100 
ASP OD1    O  N N 101 
ASP OD2    O  N N 102 
ASP OXT    O  N N 103 
ASP H      H  N N 104 
ASP H2     H  N N 105 
ASP HA     H  N N 106 
ASP HB2    H  N N 107 
ASP HB3    H  N N 108 
ASP HD2    H  N N 109 
ASP HXT    H  N N 110 
C   OP3    O  N N 111 
C   P      P  N N 112 
C   OP1    O  N N 113 
C   OP2    O  N N 114 
C   "O5'"  O  N N 115 
C   "C5'"  C  N N 116 
C   "C4'"  C  N R 117 
C   "O4'"  O  N N 118 
C   "C3'"  C  N S 119 
C   "O3'"  O  N N 120 
C   "C2'"  C  N R 121 
C   "O2'"  O  N N 122 
C   "C1'"  C  N R 123 
C   N1     N  N N 124 
C   C2     C  N N 125 
C   O2     O  N N 126 
C   N3     N  N N 127 
C   C4     C  N N 128 
C   N4     N  N N 129 
C   C5     C  N N 130 
C   C6     C  N N 131 
C   HOP3   H  N N 132 
C   HOP2   H  N N 133 
C   "H5'"  H  N N 134 
C   "H5''" H  N N 135 
C   "H4'"  H  N N 136 
C   "H3'"  H  N N 137 
C   "HO3'" H  N N 138 
C   "H2'"  H  N N 139 
C   "HO2'" H  N N 140 
C   "H1'"  H  N N 141 
C   H41    H  N N 142 
C   H42    H  N N 143 
C   H5     H  N N 144 
C   H6     H  N N 145 
CYS N      N  N N 146 
CYS CA     C  N R 147 
CYS C      C  N N 148 
CYS O      O  N N 149 
CYS CB     C  N N 150 
CYS SG     S  N N 151 
CYS OXT    O  N N 152 
CYS H      H  N N 153 
CYS H2     H  N N 154 
CYS HA     H  N N 155 
CYS HB2    H  N N 156 
CYS HB3    H  N N 157 
CYS HG     H  N N 158 
CYS HXT    H  N N 159 
G   OP3    O  N N 160 
G   P      P  N N 161 
G   OP1    O  N N 162 
G   OP2    O  N N 163 
G   "O5'"  O  N N 164 
G   "C5'"  C  N N 165 
G   "C4'"  C  N R 166 
G   "O4'"  O  N N 167 
G   "C3'"  C  N S 168 
G   "O3'"  O  N N 169 
G   "C2'"  C  N R 170 
G   "O2'"  O  N N 171 
G   "C1'"  C  N R 172 
G   N9     N  Y N 173 
G   C8     C  Y N 174 
G   N7     N  Y N 175 
G   C5     C  Y N 176 
G   C6     C  N N 177 
G   O6     O  N N 178 
G   N1     N  N N 179 
G   C2     C  N N 180 
G   N2     N  N N 181 
G   N3     N  N N 182 
G   C4     C  Y N 183 
G   HOP3   H  N N 184 
G   HOP2   H  N N 185 
G   "H5'"  H  N N 186 
G   "H5''" H  N N 187 
G   "H4'"  H  N N 188 
G   "H3'"  H  N N 189 
G   "HO3'" H  N N 190 
G   "H2'"  H  N N 191 
G   "HO2'" H  N N 192 
G   "H1'"  H  N N 193 
G   H8     H  N N 194 
G   H1     H  N N 195 
G   H21    H  N N 196 
G   H22    H  N N 197 
GLN N      N  N N 198 
GLN CA     C  N S 199 
GLN C      C  N N 200 
GLN O      O  N N 201 
GLN CB     C  N N 202 
GLN CG     C  N N 203 
GLN CD     C  N N 204 
GLN OE1    O  N N 205 
GLN NE2    N  N N 206 
GLN OXT    O  N N 207 
GLN H      H  N N 208 
GLN H2     H  N N 209 
GLN HA     H  N N 210 
GLN HB2    H  N N 211 
GLN HB3    H  N N 212 
GLN HG2    H  N N 213 
GLN HG3    H  N N 214 
GLN HE21   H  N N 215 
GLN HE22   H  N N 216 
GLN HXT    H  N N 217 
GLU N      N  N N 218 
GLU CA     C  N S 219 
GLU C      C  N N 220 
GLU O      O  N N 221 
GLU CB     C  N N 222 
GLU CG     C  N N 223 
GLU CD     C  N N 224 
GLU OE1    O  N N 225 
GLU OE2    O  N N 226 
GLU OXT    O  N N 227 
GLU H      H  N N 228 
GLU H2     H  N N 229 
GLU HA     H  N N 230 
GLU HB2    H  N N 231 
GLU HB3    H  N N 232 
GLU HG2    H  N N 233 
GLU HG3    H  N N 234 
GLU HE2    H  N N 235 
GLU HXT    H  N N 236 
GLY N      N  N N 237 
GLY CA     C  N N 238 
GLY C      C  N N 239 
GLY O      O  N N 240 
GLY OXT    O  N N 241 
GLY H      H  N N 242 
GLY H2     H  N N 243 
GLY HA2    H  N N 244 
GLY HA3    H  N N 245 
GLY HXT    H  N N 246 
GTP PG     P  N N 247 
GTP O1G    O  N N 248 
GTP O2G    O  N N 249 
GTP O3G    O  N N 250 
GTP O3B    O  N N 251 
GTP PB     P  N N 252 
GTP O1B    O  N N 253 
GTP O2B    O  N N 254 
GTP O3A    O  N N 255 
GTP PA     P  N N 256 
GTP O1A    O  N N 257 
GTP O2A    O  N N 258 
GTP "O5'"  O  N N 259 
GTP "C5'"  C  N N 260 
GTP "C4'"  C  N R 261 
GTP "O4'"  O  N N 262 
GTP "C3'"  C  N S 263 
GTP "O3'"  O  N N 264 
GTP "C2'"  C  N R 265 
GTP "O2'"  O  N N 266 
GTP "C1'"  C  N R 267 
GTP N9     N  Y N 268 
GTP C8     C  Y N 269 
GTP N7     N  Y N 270 
GTP C5     C  Y N 271 
GTP C6     C  N N 272 
GTP O6     O  N N 273 
GTP N1     N  N N 274 
GTP C2     C  N N 275 
GTP N2     N  N N 276 
GTP N3     N  N N 277 
GTP C4     C  Y N 278 
GTP HOG2   H  N N 279 
GTP HOG3   H  N N 280 
GTP HOB2   H  N N 281 
GTP HOA2   H  N N 282 
GTP "H5'"  H  N N 283 
GTP "H5''" H  N N 284 
GTP "H4'"  H  N N 285 
GTP "H3'"  H  N N 286 
GTP "HO3'" H  N N 287 
GTP "H2'"  H  N N 288 
GTP "HO2'" H  N N 289 
GTP "H1'"  H  N N 290 
GTP H8     H  N N 291 
GTP HN1    H  N N 292 
GTP HN21   H  N N 293 
GTP HN22   H  N N 294 
HIS N      N  N N 295 
HIS CA     C  N S 296 
HIS C      C  N N 297 
HIS O      O  N N 298 
HIS CB     C  N N 299 
HIS CG     C  Y N 300 
HIS ND1    N  Y N 301 
HIS CD2    C  Y N 302 
HIS CE1    C  Y N 303 
HIS NE2    N  Y N 304 
HIS OXT    O  N N 305 
HIS H      H  N N 306 
HIS H2     H  N N 307 
HIS HA     H  N N 308 
HIS HB2    H  N N 309 
HIS HB3    H  N N 310 
HIS HD1    H  N N 311 
HIS HD2    H  N N 312 
HIS HE1    H  N N 313 
HIS HE2    H  N N 314 
HIS HXT    H  N N 315 
HOH O      O  N N 316 
HOH H1     H  N N 317 
HOH H2     H  N N 318 
ILE N      N  N N 319 
ILE CA     C  N S 320 
ILE C      C  N N 321 
ILE O      O  N N 322 
ILE CB     C  N S 323 
ILE CG1    C  N N 324 
ILE CG2    C  N N 325 
ILE CD1    C  N N 326 
ILE OXT    O  N N 327 
ILE H      H  N N 328 
ILE H2     H  N N 329 
ILE HA     H  N N 330 
ILE HB     H  N N 331 
ILE HG12   H  N N 332 
ILE HG13   H  N N 333 
ILE HG21   H  N N 334 
ILE HG22   H  N N 335 
ILE HG23   H  N N 336 
ILE HD11   H  N N 337 
ILE HD12   H  N N 338 
ILE HD13   H  N N 339 
ILE HXT    H  N N 340 
LEU N      N  N N 341 
LEU CA     C  N S 342 
LEU C      C  N N 343 
LEU O      O  N N 344 
LEU CB     C  N N 345 
LEU CG     C  N N 346 
LEU CD1    C  N N 347 
LEU CD2    C  N N 348 
LEU OXT    O  N N 349 
LEU H      H  N N 350 
LEU H2     H  N N 351 
LEU HA     H  N N 352 
LEU HB2    H  N N 353 
LEU HB3    H  N N 354 
LEU HG     H  N N 355 
LEU HD11   H  N N 356 
LEU HD12   H  N N 357 
LEU HD13   H  N N 358 
LEU HD21   H  N N 359 
LEU HD22   H  N N 360 
LEU HD23   H  N N 361 
LEU HXT    H  N N 362 
LYS N      N  N N 363 
LYS CA     C  N S 364 
LYS C      C  N N 365 
LYS O      O  N N 366 
LYS CB     C  N N 367 
LYS CG     C  N N 368 
LYS CD     C  N N 369 
LYS CE     C  N N 370 
LYS NZ     N  N N 371 
LYS OXT    O  N N 372 
LYS H      H  N N 373 
LYS H2     H  N N 374 
LYS HA     H  N N 375 
LYS HB2    H  N N 376 
LYS HB3    H  N N 377 
LYS HG2    H  N N 378 
LYS HG3    H  N N 379 
LYS HD2    H  N N 380 
LYS HD3    H  N N 381 
LYS HE2    H  N N 382 
LYS HE3    H  N N 383 
LYS HZ1    H  N N 384 
LYS HZ2    H  N N 385 
LYS HZ3    H  N N 386 
LYS HXT    H  N N 387 
MET N      N  N N 388 
MET CA     C  N S 389 
MET C      C  N N 390 
MET O      O  N N 391 
MET CB     C  N N 392 
MET CG     C  N N 393 
MET SD     S  N N 394 
MET CE     C  N N 395 
MET OXT    O  N N 396 
MET H      H  N N 397 
MET H2     H  N N 398 
MET HA     H  N N 399 
MET HB2    H  N N 400 
MET HB3    H  N N 401 
MET HG2    H  N N 402 
MET HG3    H  N N 403 
MET HE1    H  N N 404 
MET HE2    H  N N 405 
MET HE3    H  N N 406 
MET HXT    H  N N 407 
MG  MG     MG N N 408 
PHE N      N  N N 409 
PHE CA     C  N S 410 
PHE C      C  N N 411 
PHE O      O  N N 412 
PHE CB     C  N N 413 
PHE CG     C  Y N 414 
PHE CD1    C  Y N 415 
PHE CD2    C  Y N 416 
PHE CE1    C  Y N 417 
PHE CE2    C  Y N 418 
PHE CZ     C  Y N 419 
PHE OXT    O  N N 420 
PHE H      H  N N 421 
PHE H2     H  N N 422 
PHE HA     H  N N 423 
PHE HB2    H  N N 424 
PHE HB3    H  N N 425 
PHE HD1    H  N N 426 
PHE HD2    H  N N 427 
PHE HE1    H  N N 428 
PHE HE2    H  N N 429 
PHE HZ     H  N N 430 
PHE HXT    H  N N 431 
PRO N      N  N N 432 
PRO CA     C  N S 433 
PRO C      C  N N 434 
PRO O      O  N N 435 
PRO CB     C  N N 436 
PRO CG     C  N N 437 
PRO CD     C  N N 438 
PRO OXT    O  N N 439 
PRO H      H  N N 440 
PRO HA     H  N N 441 
PRO HB2    H  N N 442 
PRO HB3    H  N N 443 
PRO HG2    H  N N 444 
PRO HG3    H  N N 445 
PRO HD2    H  N N 446 
PRO HD3    H  N N 447 
PRO HXT    H  N N 448 
SAM N      N  N N 449 
SAM CA     C  N S 450 
SAM C      C  N N 451 
SAM O      O  N N 452 
SAM OXT    O  N N 453 
SAM CB     C  N N 454 
SAM CG     C  N N 455 
SAM SD     S  N S 456 
SAM CE     C  N N 457 
SAM "C5'"  C  N N 458 
SAM "C4'"  C  N S 459 
SAM "O4'"  O  N N 460 
SAM "C3'"  C  N S 461 
SAM "O3'"  O  N N 462 
SAM "C2'"  C  N R 463 
SAM "O2'"  O  N N 464 
SAM "C1'"  C  N R 465 
SAM N9     N  Y N 466 
SAM C8     C  Y N 467 
SAM N7     N  Y N 468 
SAM C5     C  Y N 469 
SAM C6     C  Y N 470 
SAM N6     N  N N 471 
SAM N1     N  Y N 472 
SAM C2     C  Y N 473 
SAM N3     N  Y N 474 
SAM C4     C  Y N 475 
SAM HN1    H  N N 476 
SAM HN2    H  N N 477 
SAM HA     H  N N 478 
SAM HB1    H  N N 479 
SAM HB2    H  N N 480 
SAM HG1    H  N N 481 
SAM HG2    H  N N 482 
SAM HE1    H  N N 483 
SAM HE2    H  N N 484 
SAM HE3    H  N N 485 
SAM "H5'1" H  N N 486 
SAM "H5'2" H  N N 487 
SAM "H4'"  H  N N 488 
SAM "H3'"  H  N N 489 
SAM "HO3'" H  N N 490 
SAM "H2'"  H  N N 491 
SAM "HO2'" H  N N 492 
SAM "H1'"  H  N N 493 
SAM H8     H  N N 494 
SAM HN61   H  N N 495 
SAM HN62   H  N N 496 
SAM H2     H  N N 497 
SER N      N  N N 498 
SER CA     C  N S 499 
SER C      C  N N 500 
SER O      O  N N 501 
SER CB     C  N N 502 
SER OG     O  N N 503 
SER OXT    O  N N 504 
SER H      H  N N 505 
SER H2     H  N N 506 
SER HA     H  N N 507 
SER HB2    H  N N 508 
SER HB3    H  N N 509 
SER HG     H  N N 510 
SER HXT    H  N N 511 
THR N      N  N N 512 
THR CA     C  N S 513 
THR C      C  N N 514 
THR O      O  N N 515 
THR CB     C  N R 516 
THR OG1    O  N N 517 
THR CG2    C  N N 518 
THR OXT    O  N N 519 
THR H      H  N N 520 
THR H2     H  N N 521 
THR HA     H  N N 522 
THR HB     H  N N 523 
THR HG1    H  N N 524 
THR HG21   H  N N 525 
THR HG22   H  N N 526 
THR HG23   H  N N 527 
THR HXT    H  N N 528 
TRP N      N  N N 529 
TRP CA     C  N S 530 
TRP C      C  N N 531 
TRP O      O  N N 532 
TRP CB     C  N N 533 
TRP CG     C  Y N 534 
TRP CD1    C  Y N 535 
TRP CD2    C  Y N 536 
TRP NE1    N  Y N 537 
TRP CE2    C  Y N 538 
TRP CE3    C  Y N 539 
TRP CZ2    C  Y N 540 
TRP CZ3    C  Y N 541 
TRP CH2    C  Y N 542 
TRP OXT    O  N N 543 
TRP H      H  N N 544 
TRP H2     H  N N 545 
TRP HA     H  N N 546 
TRP HB2    H  N N 547 
TRP HB3    H  N N 548 
TRP HD1    H  N N 549 
TRP HE1    H  N N 550 
TRP HE3    H  N N 551 
TRP HZ2    H  N N 552 
TRP HZ3    H  N N 553 
TRP HH2    H  N N 554 
TRP HXT    H  N N 555 
TYR N      N  N N 556 
TYR CA     C  N S 557 
TYR C      C  N N 558 
TYR O      O  N N 559 
TYR CB     C  N N 560 
TYR CG     C  Y N 561 
TYR CD1    C  Y N 562 
TYR CD2    C  Y N 563 
TYR CE1    C  Y N 564 
TYR CE2    C  Y N 565 
TYR CZ     C  Y N 566 
TYR OH     O  N N 567 
TYR OXT    O  N N 568 
TYR H      H  N N 569 
TYR H2     H  N N 570 
TYR HA     H  N N 571 
TYR HB2    H  N N 572 
TYR HB3    H  N N 573 
TYR HD1    H  N N 574 
TYR HD2    H  N N 575 
TYR HE1    H  N N 576 
TYR HE2    H  N N 577 
TYR HH     H  N N 578 
TYR HXT    H  N N 579 
U   OP3    O  N N 580 
U   P      P  N N 581 
U   OP1    O  N N 582 
U   OP2    O  N N 583 
U   "O5'"  O  N N 584 
U   "C5'"  C  N N 585 
U   "C4'"  C  N R 586 
U   "O4'"  O  N N 587 
U   "C3'"  C  N S 588 
U   "O3'"  O  N N 589 
U   "C2'"  C  N R 590 
U   "O2'"  O  N N 591 
U   "C1'"  C  N R 592 
U   N1     N  N N 593 
U   C2     C  N N 594 
U   O2     O  N N 595 
U   N3     N  N N 596 
U   C4     C  N N 597 
U   O4     O  N N 598 
U   C5     C  N N 599 
U   C6     C  N N 600 
U   HOP3   H  N N 601 
U   HOP2   H  N N 602 
U   "H5'"  H  N N 603 
U   "H5''" H  N N 604 
U   "H4'"  H  N N 605 
U   "H3'"  H  N N 606 
U   "HO3'" H  N N 607 
U   "H2'"  H  N N 608 
U   "HO2'" H  N N 609 
U   "H1'"  H  N N 610 
U   H3     H  N N 611 
U   H5     H  N N 612 
U   H6     H  N N 613 
VAL N      N  N N 614 
VAL CA     C  N S 615 
VAL C      C  N N 616 
VAL O      O  N N 617 
VAL CB     C  N N 618 
VAL CG1    C  N N 619 
VAL CG2    C  N N 620 
VAL OXT    O  N N 621 
VAL H      H  N N 622 
VAL H2     H  N N 623 
VAL HA     H  N N 624 
VAL HB     H  N N 625 
VAL HG11   H  N N 626 
VAL HG12   H  N N 627 
VAL HG13   H  N N 628 
VAL HG21   H  N N 629 
VAL HG22   H  N N 630 
VAL HG23   H  N N 631 
VAL HXT    H  N N 632 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A   OP3   P      sing N N 1   
A   OP3   HOP3   sing N N 2   
A   P     OP1    doub N N 3   
A   P     OP2    sing N N 4   
A   P     "O5'"  sing N N 5   
A   OP2   HOP2   sing N N 6   
A   "O5'" "C5'"  sing N N 7   
A   "C5'" "C4'"  sing N N 8   
A   "C5'" "H5'"  sing N N 9   
A   "C5'" "H5''" sing N N 10  
A   "C4'" "O4'"  sing N N 11  
A   "C4'" "C3'"  sing N N 12  
A   "C4'" "H4'"  sing N N 13  
A   "O4'" "C1'"  sing N N 14  
A   "C3'" "O3'"  sing N N 15  
A   "C3'" "C2'"  sing N N 16  
A   "C3'" "H3'"  sing N N 17  
A   "O3'" "HO3'" sing N N 18  
A   "C2'" "O2'"  sing N N 19  
A   "C2'" "C1'"  sing N N 20  
A   "C2'" "H2'"  sing N N 21  
A   "O2'" "HO2'" sing N N 22  
A   "C1'" N9     sing N N 23  
A   "C1'" "H1'"  sing N N 24  
A   N9    C8     sing Y N 25  
A   N9    C4     sing Y N 26  
A   C8    N7     doub Y N 27  
A   C8    H8     sing N N 28  
A   N7    C5     sing Y N 29  
A   C5    C6     sing Y N 30  
A   C5    C4     doub Y N 31  
A   C6    N6     sing N N 32  
A   C6    N1     doub Y N 33  
A   N6    H61    sing N N 34  
A   N6    H62    sing N N 35  
A   N1    C2     sing Y N 36  
A   C2    N3     doub Y N 37  
A   C2    H2     sing N N 38  
A   N3    C4     sing Y N 39  
ALA N     CA     sing N N 40  
ALA N     H      sing N N 41  
ALA N     H2     sing N N 42  
ALA CA    C      sing N N 43  
ALA CA    CB     sing N N 44  
ALA CA    HA     sing N N 45  
ALA C     O      doub N N 46  
ALA C     OXT    sing N N 47  
ALA CB    HB1    sing N N 48  
ALA CB    HB2    sing N N 49  
ALA CB    HB3    sing N N 50  
ALA OXT   HXT    sing N N 51  
ARG N     CA     sing N N 52  
ARG N     H      sing N N 53  
ARG N     H2     sing N N 54  
ARG CA    C      sing N N 55  
ARG CA    CB     sing N N 56  
ARG CA    HA     sing N N 57  
ARG C     O      doub N N 58  
ARG C     OXT    sing N N 59  
ARG CB    CG     sing N N 60  
ARG CB    HB2    sing N N 61  
ARG CB    HB3    sing N N 62  
ARG CG    CD     sing N N 63  
ARG CG    HG2    sing N N 64  
ARG CG    HG3    sing N N 65  
ARG CD    NE     sing N N 66  
ARG CD    HD2    sing N N 67  
ARG CD    HD3    sing N N 68  
ARG NE    CZ     sing N N 69  
ARG NE    HE     sing N N 70  
ARG CZ    NH1    sing N N 71  
ARG CZ    NH2    doub N N 72  
ARG NH1   HH11   sing N N 73  
ARG NH1   HH12   sing N N 74  
ARG NH2   HH21   sing N N 75  
ARG NH2   HH22   sing N N 76  
ARG OXT   HXT    sing N N 77  
ASN N     CA     sing N N 78  
ASN N     H      sing N N 79  
ASN N     H2     sing N N 80  
ASN CA    C      sing N N 81  
ASN CA    CB     sing N N 82  
ASN CA    HA     sing N N 83  
ASN C     O      doub N N 84  
ASN C     OXT    sing N N 85  
ASN CB    CG     sing N N 86  
ASN CB    HB2    sing N N 87  
ASN CB    HB3    sing N N 88  
ASN CG    OD1    doub N N 89  
ASN CG    ND2    sing N N 90  
ASN ND2   HD21   sing N N 91  
ASN ND2   HD22   sing N N 92  
ASN OXT   HXT    sing N N 93  
ASP N     CA     sing N N 94  
ASP N     H      sing N N 95  
ASP N     H2     sing N N 96  
ASP CA    C      sing N N 97  
ASP CA    CB     sing N N 98  
ASP CA    HA     sing N N 99  
ASP C     O      doub N N 100 
ASP C     OXT    sing N N 101 
ASP CB    CG     sing N N 102 
ASP CB    HB2    sing N N 103 
ASP CB    HB3    sing N N 104 
ASP CG    OD1    doub N N 105 
ASP CG    OD2    sing N N 106 
ASP OD2   HD2    sing N N 107 
ASP OXT   HXT    sing N N 108 
C   OP3   P      sing N N 109 
C   OP3   HOP3   sing N N 110 
C   P     OP1    doub N N 111 
C   P     OP2    sing N N 112 
C   P     "O5'"  sing N N 113 
C   OP2   HOP2   sing N N 114 
C   "O5'" "C5'"  sing N N 115 
C   "C5'" "C4'"  sing N N 116 
C   "C5'" "H5'"  sing N N 117 
C   "C5'" "H5''" sing N N 118 
C   "C4'" "O4'"  sing N N 119 
C   "C4'" "C3'"  sing N N 120 
C   "C4'" "H4'"  sing N N 121 
C   "O4'" "C1'"  sing N N 122 
C   "C3'" "O3'"  sing N N 123 
C   "C3'" "C2'"  sing N N 124 
C   "C3'" "H3'"  sing N N 125 
C   "O3'" "HO3'" sing N N 126 
C   "C2'" "O2'"  sing N N 127 
C   "C2'" "C1'"  sing N N 128 
C   "C2'" "H2'"  sing N N 129 
C   "O2'" "HO2'" sing N N 130 
C   "C1'" N1     sing N N 131 
C   "C1'" "H1'"  sing N N 132 
C   N1    C2     sing N N 133 
C   N1    C6     sing N N 134 
C   C2    O2     doub N N 135 
C   C2    N3     sing N N 136 
C   N3    C4     doub N N 137 
C   C4    N4     sing N N 138 
C   C4    C5     sing N N 139 
C   N4    H41    sing N N 140 
C   N4    H42    sing N N 141 
C   C5    C6     doub N N 142 
C   C5    H5     sing N N 143 
C   C6    H6     sing N N 144 
CYS N     CA     sing N N 145 
CYS N     H      sing N N 146 
CYS N     H2     sing N N 147 
CYS CA    C      sing N N 148 
CYS CA    CB     sing N N 149 
CYS CA    HA     sing N N 150 
CYS C     O      doub N N 151 
CYS C     OXT    sing N N 152 
CYS CB    SG     sing N N 153 
CYS CB    HB2    sing N N 154 
CYS CB    HB3    sing N N 155 
CYS SG    HG     sing N N 156 
CYS OXT   HXT    sing N N 157 
G   OP3   P      sing N N 158 
G   OP3   HOP3   sing N N 159 
G   P     OP1    doub N N 160 
G   P     OP2    sing N N 161 
G   P     "O5'"  sing N N 162 
G   OP2   HOP2   sing N N 163 
G   "O5'" "C5'"  sing N N 164 
G   "C5'" "C4'"  sing N N 165 
G   "C5'" "H5'"  sing N N 166 
G   "C5'" "H5''" sing N N 167 
G   "C4'" "O4'"  sing N N 168 
G   "C4'" "C3'"  sing N N 169 
G   "C4'" "H4'"  sing N N 170 
G   "O4'" "C1'"  sing N N 171 
G   "C3'" "O3'"  sing N N 172 
G   "C3'" "C2'"  sing N N 173 
G   "C3'" "H3'"  sing N N 174 
G   "O3'" "HO3'" sing N N 175 
G   "C2'" "O2'"  sing N N 176 
G   "C2'" "C1'"  sing N N 177 
G   "C2'" "H2'"  sing N N 178 
G   "O2'" "HO2'" sing N N 179 
G   "C1'" N9     sing N N 180 
G   "C1'" "H1'"  sing N N 181 
G   N9    C8     sing Y N 182 
G   N9    C4     sing Y N 183 
G   C8    N7     doub Y N 184 
G   C8    H8     sing N N 185 
G   N7    C5     sing Y N 186 
G   C5    C6     sing N N 187 
G   C5    C4     doub Y N 188 
G   C6    O6     doub N N 189 
G   C6    N1     sing N N 190 
G   N1    C2     sing N N 191 
G   N1    H1     sing N N 192 
G   C2    N2     sing N N 193 
G   C2    N3     doub N N 194 
G   N2    H21    sing N N 195 
G   N2    H22    sing N N 196 
G   N3    C4     sing N N 197 
GLN N     CA     sing N N 198 
GLN N     H      sing N N 199 
GLN N     H2     sing N N 200 
GLN CA    C      sing N N 201 
GLN CA    CB     sing N N 202 
GLN CA    HA     sing N N 203 
GLN C     O      doub N N 204 
GLN C     OXT    sing N N 205 
GLN CB    CG     sing N N 206 
GLN CB    HB2    sing N N 207 
GLN CB    HB3    sing N N 208 
GLN CG    CD     sing N N 209 
GLN CG    HG2    sing N N 210 
GLN CG    HG3    sing N N 211 
GLN CD    OE1    doub N N 212 
GLN CD    NE2    sing N N 213 
GLN NE2   HE21   sing N N 214 
GLN NE2   HE22   sing N N 215 
GLN OXT   HXT    sing N N 216 
GLU N     CA     sing N N 217 
GLU N     H      sing N N 218 
GLU N     H2     sing N N 219 
GLU CA    C      sing N N 220 
GLU CA    CB     sing N N 221 
GLU CA    HA     sing N N 222 
GLU C     O      doub N N 223 
GLU C     OXT    sing N N 224 
GLU CB    CG     sing N N 225 
GLU CB    HB2    sing N N 226 
GLU CB    HB3    sing N N 227 
GLU CG    CD     sing N N 228 
GLU CG    HG2    sing N N 229 
GLU CG    HG3    sing N N 230 
GLU CD    OE1    doub N N 231 
GLU CD    OE2    sing N N 232 
GLU OE2   HE2    sing N N 233 
GLU OXT   HXT    sing N N 234 
GLY N     CA     sing N N 235 
GLY N     H      sing N N 236 
GLY N     H2     sing N N 237 
GLY CA    C      sing N N 238 
GLY CA    HA2    sing N N 239 
GLY CA    HA3    sing N N 240 
GLY C     O      doub N N 241 
GLY C     OXT    sing N N 242 
GLY OXT   HXT    sing N N 243 
GTP PG    O1G    doub N N 244 
GTP PG    O2G    sing N N 245 
GTP PG    O3G    sing N N 246 
GTP PG    O3B    sing N N 247 
GTP O2G   HOG2   sing N N 248 
GTP O3G   HOG3   sing N N 249 
GTP O3B   PB     sing N N 250 
GTP PB    O1B    doub N N 251 
GTP PB    O2B    sing N N 252 
GTP PB    O3A    sing N N 253 
GTP O2B   HOB2   sing N N 254 
GTP O3A   PA     sing N N 255 
GTP PA    O1A    doub N N 256 
GTP PA    O2A    sing N N 257 
GTP PA    "O5'"  sing N N 258 
GTP O2A   HOA2   sing N N 259 
GTP "O5'" "C5'"  sing N N 260 
GTP "C5'" "C4'"  sing N N 261 
GTP "C5'" "H5'"  sing N N 262 
GTP "C5'" "H5''" sing N N 263 
GTP "C4'" "O4'"  sing N N 264 
GTP "C4'" "C3'"  sing N N 265 
GTP "C4'" "H4'"  sing N N 266 
GTP "O4'" "C1'"  sing N N 267 
GTP "C3'" "O3'"  sing N N 268 
GTP "C3'" "C2'"  sing N N 269 
GTP "C3'" "H3'"  sing N N 270 
GTP "O3'" "HO3'" sing N N 271 
GTP "C2'" "O2'"  sing N N 272 
GTP "C2'" "C1'"  sing N N 273 
GTP "C2'" "H2'"  sing N N 274 
GTP "O2'" "HO2'" sing N N 275 
GTP "C1'" N9     sing N N 276 
GTP "C1'" "H1'"  sing N N 277 
GTP N9    C8     sing Y N 278 
GTP N9    C4     sing Y N 279 
GTP C8    N7     doub Y N 280 
GTP C8    H8     sing N N 281 
GTP N7    C5     sing Y N 282 
GTP C5    C6     sing N N 283 
GTP C5    C4     doub Y N 284 
GTP C6    O6     doub N N 285 
GTP C6    N1     sing N N 286 
GTP N1    C2     sing N N 287 
GTP N1    HN1    sing N N 288 
GTP C2    N2     sing N N 289 
GTP C2    N3     doub N N 290 
GTP N2    HN21   sing N N 291 
GTP N2    HN22   sing N N 292 
GTP N3    C4     sing N N 293 
HIS N     CA     sing N N 294 
HIS N     H      sing N N 295 
HIS N     H2     sing N N 296 
HIS CA    C      sing N N 297 
HIS CA    CB     sing N N 298 
HIS CA    HA     sing N N 299 
HIS C     O      doub N N 300 
HIS C     OXT    sing N N 301 
HIS CB    CG     sing N N 302 
HIS CB    HB2    sing N N 303 
HIS CB    HB3    sing N N 304 
HIS CG    ND1    sing Y N 305 
HIS CG    CD2    doub Y N 306 
HIS ND1   CE1    doub Y N 307 
HIS ND1   HD1    sing N N 308 
HIS CD2   NE2    sing Y N 309 
HIS CD2   HD2    sing N N 310 
HIS CE1   NE2    sing Y N 311 
HIS CE1   HE1    sing N N 312 
HIS NE2   HE2    sing N N 313 
HIS OXT   HXT    sing N N 314 
HOH O     H1     sing N N 315 
HOH O     H2     sing N N 316 
ILE N     CA     sing N N 317 
ILE N     H      sing N N 318 
ILE N     H2     sing N N 319 
ILE CA    C      sing N N 320 
ILE CA    CB     sing N N 321 
ILE CA    HA     sing N N 322 
ILE C     O      doub N N 323 
ILE C     OXT    sing N N 324 
ILE CB    CG1    sing N N 325 
ILE CB    CG2    sing N N 326 
ILE CB    HB     sing N N 327 
ILE CG1   CD1    sing N N 328 
ILE CG1   HG12   sing N N 329 
ILE CG1   HG13   sing N N 330 
ILE CG2   HG21   sing N N 331 
ILE CG2   HG22   sing N N 332 
ILE CG2   HG23   sing N N 333 
ILE CD1   HD11   sing N N 334 
ILE CD1   HD12   sing N N 335 
ILE CD1   HD13   sing N N 336 
ILE OXT   HXT    sing N N 337 
LEU N     CA     sing N N 338 
LEU N     H      sing N N 339 
LEU N     H2     sing N N 340 
LEU CA    C      sing N N 341 
LEU CA    CB     sing N N 342 
LEU CA    HA     sing N N 343 
LEU C     O      doub N N 344 
LEU C     OXT    sing N N 345 
LEU CB    CG     sing N N 346 
LEU CB    HB2    sing N N 347 
LEU CB    HB3    sing N N 348 
LEU CG    CD1    sing N N 349 
LEU CG    CD2    sing N N 350 
LEU CG    HG     sing N N 351 
LEU CD1   HD11   sing N N 352 
LEU CD1   HD12   sing N N 353 
LEU CD1   HD13   sing N N 354 
LEU CD2   HD21   sing N N 355 
LEU CD2   HD22   sing N N 356 
LEU CD2   HD23   sing N N 357 
LEU OXT   HXT    sing N N 358 
LYS N     CA     sing N N 359 
LYS N     H      sing N N 360 
LYS N     H2     sing N N 361 
LYS CA    C      sing N N 362 
LYS CA    CB     sing N N 363 
LYS CA    HA     sing N N 364 
LYS C     O      doub N N 365 
LYS C     OXT    sing N N 366 
LYS CB    CG     sing N N 367 
LYS CB    HB2    sing N N 368 
LYS CB    HB3    sing N N 369 
LYS CG    CD     sing N N 370 
LYS CG    HG2    sing N N 371 
LYS CG    HG3    sing N N 372 
LYS CD    CE     sing N N 373 
LYS CD    HD2    sing N N 374 
LYS CD    HD3    sing N N 375 
LYS CE    NZ     sing N N 376 
LYS CE    HE2    sing N N 377 
LYS CE    HE3    sing N N 378 
LYS NZ    HZ1    sing N N 379 
LYS NZ    HZ2    sing N N 380 
LYS NZ    HZ3    sing N N 381 
LYS OXT   HXT    sing N N 382 
MET N     CA     sing N N 383 
MET N     H      sing N N 384 
MET N     H2     sing N N 385 
MET CA    C      sing N N 386 
MET CA    CB     sing N N 387 
MET CA    HA     sing N N 388 
MET C     O      doub N N 389 
MET C     OXT    sing N N 390 
MET CB    CG     sing N N 391 
MET CB    HB2    sing N N 392 
MET CB    HB3    sing N N 393 
MET CG    SD     sing N N 394 
MET CG    HG2    sing N N 395 
MET CG    HG3    sing N N 396 
MET SD    CE     sing N N 397 
MET CE    HE1    sing N N 398 
MET CE    HE2    sing N N 399 
MET CE    HE3    sing N N 400 
MET OXT   HXT    sing N N 401 
PHE N     CA     sing N N 402 
PHE N     H      sing N N 403 
PHE N     H2     sing N N 404 
PHE CA    C      sing N N 405 
PHE CA    CB     sing N N 406 
PHE CA    HA     sing N N 407 
PHE C     O      doub N N 408 
PHE C     OXT    sing N N 409 
PHE CB    CG     sing N N 410 
PHE CB    HB2    sing N N 411 
PHE CB    HB3    sing N N 412 
PHE CG    CD1    doub Y N 413 
PHE CG    CD2    sing Y N 414 
PHE CD1   CE1    sing Y N 415 
PHE CD1   HD1    sing N N 416 
PHE CD2   CE2    doub Y N 417 
PHE CD2   HD2    sing N N 418 
PHE CE1   CZ     doub Y N 419 
PHE CE1   HE1    sing N N 420 
PHE CE2   CZ     sing Y N 421 
PHE CE2   HE2    sing N N 422 
PHE CZ    HZ     sing N N 423 
PHE OXT   HXT    sing N N 424 
PRO N     CA     sing N N 425 
PRO N     CD     sing N N 426 
PRO N     H      sing N N 427 
PRO CA    C      sing N N 428 
PRO CA    CB     sing N N 429 
PRO CA    HA     sing N N 430 
PRO C     O      doub N N 431 
PRO C     OXT    sing N N 432 
PRO CB    CG     sing N N 433 
PRO CB    HB2    sing N N 434 
PRO CB    HB3    sing N N 435 
PRO CG    CD     sing N N 436 
PRO CG    HG2    sing N N 437 
PRO CG    HG3    sing N N 438 
PRO CD    HD2    sing N N 439 
PRO CD    HD3    sing N N 440 
PRO OXT   HXT    sing N N 441 
SAM N     CA     sing N N 442 
SAM N     HN1    sing N N 443 
SAM N     HN2    sing N N 444 
SAM CA    C      sing N N 445 
SAM CA    CB     sing N N 446 
SAM CA    HA     sing N N 447 
SAM C     O      doub N N 448 
SAM C     OXT    sing N N 449 
SAM CB    CG     sing N N 450 
SAM CB    HB1    sing N N 451 
SAM CB    HB2    sing N N 452 
SAM CG    SD     sing N N 453 
SAM CG    HG1    sing N N 454 
SAM CG    HG2    sing N N 455 
SAM SD    CE     sing N N 456 
SAM SD    "C5'"  sing N N 457 
SAM CE    HE1    sing N N 458 
SAM CE    HE2    sing N N 459 
SAM CE    HE3    sing N N 460 
SAM "C5'" "C4'"  sing N N 461 
SAM "C5'" "H5'1" sing N N 462 
SAM "C5'" "H5'2" sing N N 463 
SAM "C4'" "O4'"  sing N N 464 
SAM "C4'" "C3'"  sing N N 465 
SAM "C4'" "H4'"  sing N N 466 
SAM "O4'" "C1'"  sing N N 467 
SAM "C3'" "O3'"  sing N N 468 
SAM "C3'" "C2'"  sing N N 469 
SAM "C3'" "H3'"  sing N N 470 
SAM "O3'" "HO3'" sing N N 471 
SAM "C2'" "O2'"  sing N N 472 
SAM "C2'" "C1'"  sing N N 473 
SAM "C2'" "H2'"  sing N N 474 
SAM "O2'" "HO2'" sing N N 475 
SAM "C1'" N9     sing N N 476 
SAM "C1'" "H1'"  sing N N 477 
SAM N9    C8     sing Y N 478 
SAM N9    C4     sing Y N 479 
SAM C8    N7     doub Y N 480 
SAM C8    H8     sing N N 481 
SAM N7    C5     sing Y N 482 
SAM C5    C6     sing Y N 483 
SAM C5    C4     doub Y N 484 
SAM C6    N6     sing N N 485 
SAM C6    N1     doub Y N 486 
SAM N6    HN61   sing N N 487 
SAM N6    HN62   sing N N 488 
SAM N1    C2     sing Y N 489 
SAM C2    N3     doub Y N 490 
SAM C2    H2     sing N N 491 
SAM N3    C4     sing Y N 492 
SER N     CA     sing N N 493 
SER N     H      sing N N 494 
SER N     H2     sing N N 495 
SER CA    C      sing N N 496 
SER CA    CB     sing N N 497 
SER CA    HA     sing N N 498 
SER C     O      doub N N 499 
SER C     OXT    sing N N 500 
SER CB    OG     sing N N 501 
SER CB    HB2    sing N N 502 
SER CB    HB3    sing N N 503 
SER OG    HG     sing N N 504 
SER OXT   HXT    sing N N 505 
THR N     CA     sing N N 506 
THR N     H      sing N N 507 
THR N     H2     sing N N 508 
THR CA    C      sing N N 509 
THR CA    CB     sing N N 510 
THR CA    HA     sing N N 511 
THR C     O      doub N N 512 
THR C     OXT    sing N N 513 
THR CB    OG1    sing N N 514 
THR CB    CG2    sing N N 515 
THR CB    HB     sing N N 516 
THR OG1   HG1    sing N N 517 
THR CG2   HG21   sing N N 518 
THR CG2   HG22   sing N N 519 
THR CG2   HG23   sing N N 520 
THR OXT   HXT    sing N N 521 
TRP N     CA     sing N N 522 
TRP N     H      sing N N 523 
TRP N     H2     sing N N 524 
TRP CA    C      sing N N 525 
TRP CA    CB     sing N N 526 
TRP CA    HA     sing N N 527 
TRP C     O      doub N N 528 
TRP C     OXT    sing N N 529 
TRP CB    CG     sing N N 530 
TRP CB    HB2    sing N N 531 
TRP CB    HB3    sing N N 532 
TRP CG    CD1    doub Y N 533 
TRP CG    CD2    sing Y N 534 
TRP CD1   NE1    sing Y N 535 
TRP CD1   HD1    sing N N 536 
TRP CD2   CE2    doub Y N 537 
TRP CD2   CE3    sing Y N 538 
TRP NE1   CE2    sing Y N 539 
TRP NE1   HE1    sing N N 540 
TRP CE2   CZ2    sing Y N 541 
TRP CE3   CZ3    doub Y N 542 
TRP CE3   HE3    sing N N 543 
TRP CZ2   CH2    doub Y N 544 
TRP CZ2   HZ2    sing N N 545 
TRP CZ3   CH2    sing Y N 546 
TRP CZ3   HZ3    sing N N 547 
TRP CH2   HH2    sing N N 548 
TRP OXT   HXT    sing N N 549 
TYR N     CA     sing N N 550 
TYR N     H      sing N N 551 
TYR N     H2     sing N N 552 
TYR CA    C      sing N N 553 
TYR CA    CB     sing N N 554 
TYR CA    HA     sing N N 555 
TYR C     O      doub N N 556 
TYR C     OXT    sing N N 557 
TYR CB    CG     sing N N 558 
TYR CB    HB2    sing N N 559 
TYR CB    HB3    sing N N 560 
TYR CG    CD1    doub Y N 561 
TYR CG    CD2    sing Y N 562 
TYR CD1   CE1    sing Y N 563 
TYR CD1   HD1    sing N N 564 
TYR CD2   CE2    doub Y N 565 
TYR CD2   HD2    sing N N 566 
TYR CE1   CZ     doub Y N 567 
TYR CE1   HE1    sing N N 568 
TYR CE2   CZ     sing Y N 569 
TYR CE2   HE2    sing N N 570 
TYR CZ    OH     sing N N 571 
TYR OH    HH     sing N N 572 
TYR OXT   HXT    sing N N 573 
U   OP3   P      sing N N 574 
U   OP3   HOP3   sing N N 575 
U   P     OP1    doub N N 576 
U   P     OP2    sing N N 577 
U   P     "O5'"  sing N N 578 
U   OP2   HOP2   sing N N 579 
U   "O5'" "C5'"  sing N N 580 
U   "C5'" "C4'"  sing N N 581 
U   "C5'" "H5'"  sing N N 582 
U   "C5'" "H5''" sing N N 583 
U   "C4'" "O4'"  sing N N 584 
U   "C4'" "C3'"  sing N N 585 
U   "C4'" "H4'"  sing N N 586 
U   "O4'" "C1'"  sing N N 587 
U   "C3'" "O3'"  sing N N 588 
U   "C3'" "C2'"  sing N N 589 
U   "C3'" "H3'"  sing N N 590 
U   "O3'" "HO3'" sing N N 591 
U   "C2'" "O2'"  sing N N 592 
U   "C2'" "C1'"  sing N N 593 
U   "C2'" "H2'"  sing N N 594 
U   "O2'" "HO2'" sing N N 595 
U   "C1'" N1     sing N N 596 
U   "C1'" "H1'"  sing N N 597 
U   N1    C2     sing N N 598 
U   N1    C6     sing N N 599 
U   C2    O2     doub N N 600 
U   C2    N3     sing N N 601 
U   N3    C4     sing N N 602 
U   N3    H3     sing N N 603 
U   C4    O4     doub N N 604 
U   C4    C5     sing N N 605 
U   C5    C6     doub N N 606 
U   C5    H5     sing N N 607 
U   C6    H6     sing N N 608 
VAL N     CA     sing N N 609 
VAL N     H      sing N N 610 
VAL N     H2     sing N N 611 
VAL CA    C      sing N N 612 
VAL CA    CB     sing N N 613 
VAL CA    HA     sing N N 614 
VAL C     O      doub N N 615 
VAL C     OXT    sing N N 616 
VAL CB    CG1    sing N N 617 
VAL CB    CG2    sing N N 618 
VAL CB    HB     sing N N 619 
VAL CG1   HG11   sing N N 620 
VAL CG1   HG12   sing N N 621 
VAL CG1   HG13   sing N N 622 
VAL CG2   HG21   sing N N 623 
VAL CG2   HG22   sing N N 624 
VAL CG2   HG23   sing N N 625 
VAL OXT   HXT    sing N N 626 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-08-01 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9GCH 
_em_admin.last_update        2024-12-25 
_em_admin.map_release_date   2024-11-20 
_em_admin.title              'Human mitochondrial RNase Z with tRNA-His-CCA, SDR5C1/TRMT10C focus' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.25 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 2 2 9606 'Homo sapiens' ? ? ? ? ? 
? ? 3 3 9606 'Homo sapiens' ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 2 2 562   'Escherichia coli'    ? ? 
? 3 3 32630 'synthetic construct' ? ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         48 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   4773315 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? Warp      1.0.9       
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?         ?           
MASKING                         ? 3  ? ? ? ?         ?           
'CTF CORRECTION'                ? 4  1 ? ? Warp      1.0.9       
'LAYERLINE INDEXING'            ? 5  ? ? ? ?         ?           
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?         ?           
'MODEL FITTING'                 ? 7  ? 1 ? Coot      0.9.8       
OTHER                           ? 8  ? ? ? ?         ?           
'INITIAL EULER ASSIGNMENT'      ? 9  1 ? ? cryoSPARC 4.3.1       
'FINAL EULER ASSIGNMENT'        ? 10 1 ? ? RELION    5.0-beta-1  
CLASSIFICATION                  ? 11 1 ? ? ?         ?           
RECONSTRUCTION                  ? 12 1 ? ? ?         ?           
'MODEL REFINEMENT'              ? 13 ? 1 ? PHENIX    1.20.1-4487 
'VOLUME SELECTION'              ? 14 1 1 1 ?         ?           
'SERIES ALIGNMENT'              ? 15 1 1 1 ?         ?           
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?         ?           
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?         ?           
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?         ?           
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?         ?           
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
9GCH 'double helix'        
9GCH 'a-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 F U 1  1_555 F A 66 1_555 0.282  -0.439 -0.537 6.071   -17.567 -0.649   1  T_U2:A67_T  T 2  ? T 67 ? 20 1 
1 F A 2  1_555 F U 65 1_555 -0.092 0.255  0.238  -4.083  -12.170 1.876    2  T_A3:U66_T  T 3  ? T 66 ? 20 1 
1 F A 3  1_555 F U 64 1_555 -0.191 0.098  0.287  5.309   -17.230 0.854    3  T_A4:U65_T  T 4  ? T 65 ? 20 1 
1 F A 4  1_555 F U 63 1_555 -0.010 -0.057 0.189  11.754  -24.446 -0.730   4  T_A5:U64_T  T 5  ? T 64 ? 20 1 
1 F U 5  1_555 F A 62 1_555 -0.251 -0.254 0.143  10.954  -32.966 2.905    5  T_U6:A63_T  T 6  ? T 63 ? 20 1 
1 F A 6  1_555 F U 61 1_555 -0.206 0.001  0.029  -6.764  -16.050 7.637    6  T_A7:U62_T  T 7  ? T 62 ? 20 1 
1 F A 44 1_555 F U 60 1_555 -0.008 0.053  -0.103 -2.814  -11.157 0.645    7  T_A45:U61_T T 45 ? T 61 ? 20 1 
1 F G 45 1_555 F C 59 1_555 -0.401 -0.027 -0.032 -9.197  -11.072 7.949    8  T_G46:C60_T T 46 ? T 60 ? 19 1 
1 F A 46 1_555 F C 58 1_555 -1.172 -0.149 -0.346 -8.520  -16.462 7.259    9  T_A47:C59_T T 47 ? T 59 ? ?  1 
1 F G 47 1_555 F C 57 1_555 0.505  0.440  0.286  -2.141  -13.235 8.937    10 T_G48:C58_T T 48 ? T 58 ? 19 1 
1 F G 48 1_555 F C 56 1_555 -0.468 -0.416 -0.303 -16.329 -32.421 -15.439  11 T_G49:C57_T T 49 ? T 57 ? 19 1 
1 F C 49 1_555 F A 55 1_555 2.910  -0.833 -0.078 -15.846 -14.555 -16.362  12 T_C50:A56_T T 50 ? T 56 ? ?  1 
1 F U 50 1_555 F C 53 1_555 6.977  -6.487 0.657  12.955  20.304  -38.570  13 T_U51:C54_T T 51 ? T 54 ? ?  4 
1 F G 9  1_555 F C 21 1_555 -0.830 -0.167 -0.227 -13.857 -5.163  2.198    14 T_G10:C22_T T 10 ? T 22 ? 19 1 
1 F U 10 1_555 F A 20 1_555 -0.031 -0.101 0.098  -6.240  -10.468 1.221    15 T_U11:A21_T T 11 ? T 21 ? 20 1 
1 F U 11 1_555 F A 19 1_555 0.242  0.122  0.226  -3.015  -13.632 0.700    16 T_U12:A20_T T 12 ? T 20 ? 20 1 
1 F U 12 1_555 F A 18 1_555 -0.134 -0.113 0.279  7.319   -10.494 11.748   17 T_U13:A19_T T 13 ? T 19 ? 20 1 
1 F A 13 1_555 F C 43 1_555 4.432  1.449  0.766  4.933   23.939  -108.937 18 T_A14:C44_T T 14 ? T 44 ? ?  ? 
1 F U 23 1_555 F A 39 1_555 0.021  0.063  -0.311 24.962  -14.122 5.307    19 T_U24:A40_T T 24 ? T 40 ? 20 1 
1 F C 24 1_555 F G 38 1_555 0.136  -0.231 -0.187 7.437   -14.740 1.962    20 T_C25:G39_T T 25 ? T 39 ? 19 1 
1 F A 25 1_555 F U 37 1_555 0.024  -0.111 0.005  -3.577  -9.387  3.144    21 T_A26:U38_T T 26 ? T 38 ? 20 1 
1 F G 26 1_555 F C 36 1_555 -0.225 0.031  -0.294 -6.778  -12.891 6.394    22 T_G27:C37_T T 27 ? T 37 ? 19 1 
1 F A 27 1_555 F U 35 1_555 0.123  -0.110 -0.657 8.355   8.917   -0.003   23 T_A28:U36_T T 28 ? T 36 ? 20 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 F U 1  1_555 F A 66 1_555 F A 2  1_555 F U 65 1_555 -0.078 -1.520 3.449 -6.620 17.757 27.358 -5.440 -0.898 2.074 32.994 12.301  
33.177 1  TT_U2A3:U66A67_TT   T 2  ? T 67 ? T 3  ? T 66 ? 
1 F A 2  1_555 F U 65 1_555 F A 3  1_555 F U 64 1_555 -0.206 -1.008 3.116 -1.189 2.430  30.724 -2.342 0.170  3.034 4.575  2.238   
30.840 2  TT_A3A4:U65U66_TT   T 3  ? T 66 ? T 4  ? T 65 ? 
1 F A 3  1_555 F U 64 1_555 F A 4  1_555 F U 63 1_555 0.175  -0.932 3.125 1.915  4.581  31.090 -2.521 0.013  2.965 8.479  -3.544  
31.474 3  TT_A4A5:U64U65_TT   T 4  ? T 65 ? T 5  ? T 64 ? 
1 F A 4  1_555 F U 63 1_555 F U 5  1_555 F A 62 1_555 1.169  -1.770 3.068 4.678  4.153  29.378 -4.209 -1.364 2.942 8.074  -9.095  
30.023 4  TT_A5U6:A63U64_TT   T 5  ? T 64 ? T 6  ? T 63 ? 
1 F U 5  1_555 F A 62 1_555 F A 6  1_555 F U 61 1_555 -0.059 -1.293 3.376 2.236  22.455 37.070 -3.818 0.286  2.264 31.956 -3.182  
43.192 5  TT_U6A7:U62A63_TT   T 6  ? T 63 ? T 7  ? T 62 ? 
1 F A 6  1_555 F U 61 1_555 F A 44 1_555 F U 60 1_555 -0.566 -1.271 3.134 0.026  7.938  32.240 -3.443 0.996  2.752 14.030 -0.046  
33.178 6  TT_A7A45:U61U62_TT  T 7  ? T 62 ? T 45 ? T 61 ? 
1 F A 44 1_555 F U 60 1_555 F G 45 1_555 F C 59 1_555 0.460  -1.840 3.382 0.206  5.696  29.987 -4.610 -0.834 2.992 10.884 -0.393  
30.511 7  TT_A45G46:C60U61_TT T 45 ? T 61 ? T 46 ? T 60 ? 
1 F G 45 1_555 F C 59 1_555 F A 46 1_555 F C 58 1_555 0.064  -1.410 3.098 0.614  11.686 30.207 -4.331 -0.021 2.402 21.440 -1.126  
32.345 8  TT_G46A47:C59C60_TT T 46 ? T 60 ? T 47 ? T 59 ? 
1 F A 46 1_555 F C 58 1_555 F G 47 1_555 F C 57 1_555 0.081  -1.442 3.133 -3.907 6.241  34.358 -3.248 -0.671 2.811 10.417 6.522   
35.115 9  TT_A47G48:C58C59_TT T 47 ? T 59 ? T 48 ? T 58 ? 
1 F G 47 1_555 F C 57 1_555 F G 48 1_555 F C 56 1_555 -0.131 -2.393 3.872 7.113  7.259  22.171 -8.099 2.690  2.787 17.728 -17.370 
24.363 10 TT_G48G49:C57C58_TT T 48 ? T 58 ? T 49 ? T 57 ? 
1 F G 48 1_555 F C 56 1_555 F C 49 1_555 F A 55 1_555 -0.034 -1.320 3.249 1.431  -2.059 52.060 -1.365 0.134  3.293 -2.344 -1.629  
52.116 11 TT_G49C50:A56C57_TT T 49 ? T 57 ? T 50 ? T 56 ? 
1 F C 49 1_555 F A 55 1_555 F U 50 1_555 F C 53 1_555 -0.641 -0.986 2.809 -1.401 0.550  61.864 -0.981 0.567  2.813 0.535  1.362   
61.880 12 TT_C50U51:C54A56_TT T 50 ? T 56 ? T 51 ? T 54 ? 
1 F G 9  1_555 F C 21 1_555 F U 10 1_555 F A 20 1_555 -0.585 -1.858 3.184 -0.851 -0.907 33.327 -3.089 0.881  3.246 -1.582 1.483   
33.349 13 TT_G10U11:A21C22_TT T 10 ? T 22 ? T 11 ? T 21 ? 
1 F U 10 1_555 F A 20 1_555 F U 11 1_555 F A 19 1_555 0.326  -1.181 3.152 2.409  6.369  33.665 -2.934 -0.200 2.903 10.858 -4.108  
34.328 14 TT_U11U12:A20A21_TT T 11 ? T 21 ? T 12 ? T 20 ? 
1 F U 11 1_555 F A 19 1_555 F U 12 1_555 F A 18 1_555 0.533  -1.092 3.165 -1.838 -1.888 27.960 -1.818 -1.520 3.189 -3.896 3.793   
28.081 15 TT_U12U13:A19A20_TT T 12 ? T 20 ? T 13 ? T 19 ? 
1 F U 12 1_555 F A 18 1_555 F A 13 1_555 F C 43 1_555 -0.174 -3.350 2.913 10.366 -5.319 99.319 -2.113 0.262  3.020 -3.480 -6.783  
99.821 16 TT_U13A14:C44A19_TT T 13 ? T 19 ? T 14 ? T 44 ? 
1 F U 23 1_555 F A 39 1_555 F C 24 1_555 F G 38 1_555 -0.373 -2.043 3.589 -2.472 9.550  36.977 -4.354 0.251  3.007 14.738 3.815   
38.225 17 TT_U24C25:G39A40_TT T 24 ? T 40 ? T 25 ? T 39 ? 
1 F C 24 1_555 F G 38 1_555 F A 25 1_555 F U 37 1_555 -0.721 -1.998 3.455 -3.141 12.101 27.855 -6.085 0.778  2.459 23.684 6.148   
30.481 18 TT_C25A26:U38G39_TT T 25 ? T 39 ? T 26 ? T 38 ? 
1 F A 25 1_555 F U 37 1_555 F G 26 1_555 F C 36 1_555 0.419  -1.604 3.317 2.971  10.018 29.186 -4.829 -0.245 2.663 19.123 -5.672  
30.962 19 TT_A26G27:C37U38_TT T 26 ? T 38 ? T 27 ? T 37 ? 
1 F G 26 1_555 F C 36 1_555 F A 27 1_555 F U 35 1_555 0.441  -1.558 2.959 4.076  16.939 24.182 -5.783 -0.199 1.601 35.181 -8.466  
29.729 20 TT_G27A28:U36C37_TT T 27 ? T 37 ? T 28 ? T 36 ? 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7ONU 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9GCH 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N     . SER A 1 7   ? 235.914 199.278 179.215 1.00 34.01  ? 7   SER A N     1 
ATOM   2     C  CA    . SER A 1 7   ? 237.072 199.423 180.141 1.00 32.80  ? 7   SER A CA    1 
ATOM   3     C  C     . SER A 1 7   ? 237.432 200.894 180.327 1.00 29.58  ? 7   SER A C     1 
ATOM   4     O  O     . SER A 1 7   ? 237.339 201.680 179.387 1.00 32.02  ? 7   SER A O     1 
ATOM   5     C  CB    . SER A 1 7   ? 238.256 198.645 179.651 1.00 35.68  ? 7   SER A CB    1 
ATOM   6     O  OG    . SER A 1 7   ? 239.308 198.700 180.600 1.00 36.05  ? 7   SER A OG    1 
ATOM   7     N  N     . VAL A 1 8   ? 237.858 201.256 181.541 1.00 27.64  ? 8   VAL A N     1 
ATOM   8     C  CA    . VAL A 1 8   ? 238.251 202.625 181.833 1.00 26.02  ? 8   VAL A CA    1 
ATOM   9     C  C     . VAL A 1 8   ? 239.755 202.819 181.652 1.00 24.86  ? 8   VAL A C     1 
ATOM   10    O  O     . VAL A 1 8   ? 240.260 203.913 181.885 1.00 25.10  ? 8   VAL A O     1 
ATOM   11    C  CB    . VAL A 1 8   ? 237.840 203.054 183.250 1.00 24.25  ? 8   VAL A CB    1 
ATOM   12    C  CG1   . VAL A 1 8   ? 236.355 202.827 183.483 1.00 24.50  ? 8   VAL A CG1   1 
ATOM   13    C  CG2   . VAL A 1 8   ? 238.671 202.362 184.311 1.00 24.52  ? 8   VAL A CG2   1 
ATOM   14    N  N     . LYS A 1 9   ? 240.481 201.774 181.263 1.00 25.49  ? 9   LYS A N     1 
ATOM   15    C  CA    . LYS A 1 9   ? 241.917 201.891 181.059 1.00 27.35  ? 9   LYS A CA    1 
ATOM   16    C  C     . LYS A 1 9   ? 242.212 202.892 179.946 1.00 24.57  ? 9   LYS A C     1 
ATOM   17    O  O     . LYS A 1 9   ? 241.652 202.803 178.864 1.00 26.03  ? 9   LYS A O     1 
ATOM   18    C  CB    . LYS A 1 9   ? 242.523 200.526 180.734 1.00 32.56  ? 9   LYS A CB    1 
ATOM   19    C  CG    . LYS A 1 9   ? 243.935 200.590 180.213 1.00 37.23  ? 9   LYS A CG    1 
ATOM   20    C  CD    . LYS A 1 9   ? 244.617 199.233 180.159 1.00 42.65  ? 9   LYS A CD    1 
ATOM   21    C  CE    . LYS A 1 9   ? 246.104 199.385 180.143 1.00 48.06  ? 9   LYS A CE    1 
ATOM   22    N  NZ    . LYS A 1 9   ? 246.634 199.649 181.488 1.00 49.44  ? 9   LYS A NZ    1 
ATOM   23    N  N     . GLY A 1 10  ? 243.103 203.846 180.234 1.00 23.85  ? 10  GLY A N     1 
ATOM   24    C  CA    . GLY A 1 10  ? 243.508 204.845 179.262 1.00 23.45  ? 10  GLY A CA    1 
ATOM   25    C  C     . GLY A 1 10  ? 242.584 206.062 179.209 1.00 21.83  ? 10  GLY A C     1 
ATOM   26    O  O     . GLY A 1 10  ? 242.932 207.045 178.564 1.00 22.43  ? 10  GLY A O     1 
ATOM   27    N  N     . LEU A 1 11  ? 241.424 206.014 179.875 1.00 19.98  ? 11  LEU A N     1 
ATOM   28    C  CA    . LEU A 1 11  ? 240.529 207.161 179.908 1.00 18.80  ? 11  LEU A CA    1 
ATOM   29    C  C     . LEU A 1 11  ? 241.089 208.235 180.838 1.00 17.69  ? 11  LEU A C     1 
ATOM   30    O  O     . LEU A 1 11  ? 241.762 207.931 181.817 1.00 18.54  ? 11  LEU A O     1 
ATOM   31    C  CB    . LEU A 1 11  ? 239.125 206.753 180.353 1.00 18.77  ? 11  LEU A CB    1 
ATOM   32    C  CG    . LEU A 1 11  ? 238.375 205.794 179.423 1.00 19.92  ? 11  LEU A CG    1 
ATOM   33    C  CD1   . LEU A 1 11  ? 236.950 205.604 179.909 1.00 20.92  ? 11  LEU A CD1   1 
ATOM   34    C  CD2   . LEU A 1 11  ? 238.369 206.259 177.980 1.00 20.52  ? 11  LEU A CD2   1 
ATOM   35    N  N     . VAL A 1 12  ? 240.779 209.495 180.522 1.00 15.82  ? 12  VAL A N     1 
ATOM   36    C  CA    . VAL A 1 12  ? 241.163 210.620 181.352 1.00 15.30  ? 12  VAL A CA    1 
ATOM   37    C  C     . VAL A 1 12  ? 239.902 211.181 181.997 1.00 14.43  ? 12  VAL A C     1 
ATOM   38    O  O     . VAL A 1 12  ? 238.963 211.565 181.296 1.00 14.01  ? 12  VAL A O     1 
ATOM   39    C  CB    . VAL A 1 12  ? 241.891 211.703 180.540 1.00 16.57  ? 12  VAL A CB    1 
ATOM   40    C  CG1   . VAL A 1 12  ? 242.285 212.891 181.408 1.00 16.35  ? 12  VAL A CG1   1 
ATOM   41    C  CG2   . VAL A 1 12  ? 243.104 211.113 179.827 1.00 17.35  ? 12  VAL A CG2   1 
ATOM   42    N  N     . ALA A 1 13  ? 239.913 211.227 183.332 1.00 12.90  ? 13  ALA A N     1 
ATOM   43    C  CA    . ALA A 1 13  ? 238.769 211.678 184.097 1.00 13.73  ? 13  ALA A CA    1 
ATOM   44    C  C     . ALA A 1 13  ? 239.122 212.967 184.825 1.00 14.39  ? 13  ALA A C     1 
ATOM   45    O  O     . ALA A 1 13  ? 240.132 213.032 185.522 1.00 15.50  ? 13  ALA A O     1 
ATOM   46    C  CB    . ALA A 1 13  ? 238.326 210.612 185.076 1.00 13.33  ? 13  ALA A CB    1 
ATOM   47    N  N     . VAL A 1 14  ? 238.271 213.981 184.657 1.00 13.87  ? 14  VAL A N     1 
ATOM   48    C  CA    . VAL A 1 14  ? 238.348 215.180 185.468 1.00 13.95  ? 14  VAL A CA    1 
ATOM   49    C  C     . VAL A 1 14  ? 237.345 215.047 186.605 1.00 13.15  ? 14  VAL A C     1 
ATOM   50    O  O     . VAL A 1 14  ? 236.148 214.973 186.364 1.00 12.87  ? 14  VAL A O     1 
ATOM   51    C  CB    . VAL A 1 14  ? 238.077 216.438 184.628 1.00 14.33  ? 14  VAL A CB    1 
ATOM   52    C  CG1   . VAL A 1 14  ? 237.988 217.674 185.510 1.00 15.19  ? 14  VAL A CG1   1 
ATOM   53    C  CG2   . VAL A 1 14  ? 239.146 216.609 183.563 1.00 15.03  ? 14  VAL A CG2   1 
ATOM   54    N  N     . ILE A 1 15  ? 237.848 215.001 187.831 1.00 13.09  ? 15  ILE A N     1 
ATOM   55    C  CA    . ILE A 1 15  ? 237.025 214.732 188.993 1.00 13.29  ? 15  ILE A CA    1 
ATOM   56    C  C     . ILE A 1 15  ? 236.970 215.976 189.860 1.00 14.26  ? 15  ILE A C     1 
ATOM   57    O  O     . ILE A 1 15  ? 237.954 216.377 190.458 1.00 14.77  ? 15  ILE A O     1 
ATOM   58    C  CB    . ILE A 1 15  ? 237.535 213.513 189.772 1.00 13.56  ? 15  ILE A CB    1 
ATOM   59    C  CG1   . ILE A 1 15  ? 237.562 212.287 188.882 1.00 13.38  ? 15  ILE A CG1   1 
ATOM   60    C  CG2   . ILE A 1 15  ? 236.678 213.287 191.010 1.00 12.73  ? 15  ILE A CG2   1 
ATOM   61    C  CD1   . ILE A 1 15  ? 238.409 211.158 189.406 1.00 14.68  ? 15  ILE A CD1   1 
ATOM   62    N  N     . THR A 1 16  ? 235.792 216.583 189.902 1.00 14.55  ? 16  THR A N     1 
ATOM   63    C  CA    . THR A 1 16  ? 235.583 217.789 190.669 1.00 16.14  ? 16  THR A CA    1 
ATOM   64    C  C     . THR A 1 16  ? 235.420 217.426 192.144 1.00 16.32  ? 16  THR A C     1 
ATOM   65    O  O     . THR A 1 16  ? 234.771 216.441 192.490 1.00 16.20  ? 16  THR A O     1 
ATOM   66    C  CB    . THR A 1 16  ? 234.338 218.467 190.105 1.00 18.77  ? 16  THR A CB    1 
ATOM   67    O  OG1   . THR A 1 16  ? 234.608 218.992 188.807 1.00 17.35  ? 16  THR A OG1   1 
ATOM   68    C  CG2   . THR A 1 16  ? 233.947 219.623 190.958 1.00 21.99  ? 16  THR A CG2   1 
ATOM   69    N  N     . GLY A 1 17  ? 235.987 218.248 193.021 1.00 16.43  ? 17  GLY A N     1 
ATOM   70    C  CA    . GLY A 1 17  ? 236.015 217.922 194.440 1.00 16.82  ? 17  GLY A CA    1 
ATOM   71    C  C     . GLY A 1 17  ? 236.807 216.635 194.708 1.00 16.86  ? 17  GLY A C     1 
ATOM   72    O  O     . GLY A 1 17  ? 236.466 215.870 195.599 1.00 17.26  ? 17  GLY A O     1 
ATOM   73    N  N     . GLY A 1 18  ? 237.876 216.402 193.934 1.00 17.38  ? 18  GLY A N     1 
ATOM   74    C  CA    . GLY A 1 18  ? 238.582 215.131 193.932 1.00 18.03  ? 18  GLY A CA    1 
ATOM   75    C  C     . GLY A 1 18  ? 239.621 214.988 195.042 1.00 18.59  ? 18  GLY A C     1 
ATOM   76    O  O     . GLY A 1 18  ? 240.277 213.953 195.116 1.00 18.99  ? 18  GLY A O     1 
ATOM   77    N  N     . ALA A 1 19  ? 239.764 215.994 195.916 1.00 19.30  ? 19  ALA A N     1 
ATOM   78    C  CA    . ALA A 1 19  ? 240.759 215.929 196.981 1.00 20.34  ? 19  ALA A CA    1 
ATOM   79    C  C     . ALA A 1 19  ? 240.251 215.176 198.208 1.00 20.20  ? 19  ALA A C     1 
ATOM   80    O  O     . ALA A 1 19  ? 241.028 214.910 199.115 1.00 21.62  ? 19  ALA A O     1 
ATOM   81    C  CB    . ALA A 1 19  ? 241.198 217.323 197.372 1.00 21.32  ? 19  ALA A CB    1 
ATOM   82    N  N     . SER A 1 20  ? 238.956 214.850 198.270 1.00 19.31  ? 20  SER A N     1 
ATOM   83    C  CA    . SER A 1 20  ? 238.406 214.191 199.444 1.00 19.91  ? 20  SER A CA    1 
ATOM   84    C  C     . SER A 1 20  ? 237.083 213.525 199.097 1.00 18.29  ? 20  SER A C     1 
ATOM   85    O  O     . SER A 1 20  ? 236.539 213.741 198.020 1.00 17.65  ? 20  SER A O     1 
ATOM   86    C  CB    . SER A 1 20  ? 238.217 215.153 200.582 1.00 21.17  ? 20  SER A CB    1 
ATOM   87    O  OG    . SER A 1 20  ? 237.414 216.242 200.169 1.00 22.99  ? 20  SER A OG    1 
ATOM   88    N  N     . GLY A 1 21  ? 236.591 212.697 200.025 1.00 16.93  ? 21  GLY A N     1 
ATOM   89    C  CA    . GLY A 1 21  ? 235.240 212.161 199.960 1.00 15.78  ? 21  GLY A CA    1 
ATOM   90    C  C     . GLY A 1 21  ? 234.998 211.337 198.697 1.00 14.56  ? 21  GLY A C     1 
ATOM   91    O  O     . GLY A 1 21  ? 235.838 210.543 198.294 1.00 14.61  ? 21  GLY A O     1 
ATOM   92    N  N     . LEU A 1 22  ? 233.840 211.555 198.069 1.00 13.80  ? 22  LEU A N     1 
ATOM   93    C  CA    . LEU A 1 22  ? 233.428 210.767 196.924 1.00 13.09  ? 22  LEU A CA    1 
ATOM   94    C  C     . LEU A 1 22  ? 234.363 210.997 195.745 1.00 12.07  ? 22  LEU A C     1 
ATOM   95    O  O     . LEU A 1 22  ? 234.688 210.055 195.031 1.00 12.71  ? 22  LEU A O     1 
ATOM   96    C  CB    . LEU A 1 22  ? 231.984 211.107 196.564 1.00 12.98  ? 22  LEU A CB    1 
ATOM   97    C  CG    . LEU A 1 22  ? 230.947 210.828 197.654 1.00 13.17  ? 22  LEU A CG    1 
ATOM   98    C  CD1   . LEU A 1 22  ? 229.562 211.132 197.119 1.00 13.68  ? 22  LEU A CD1   1 
ATOM   99    C  CD2   . LEU A 1 22  ? 231.043 209.415 198.171 1.00 13.08  ? 22  LEU A CD2   1 
ATOM   100   N  N     . GLY A 1 23  ? 234.775 212.239 195.526 1.00 11.71  ? 23  GLY A N     1 
ATOM   101   C  CA    . GLY A 1 23  ? 235.658 212.557 194.421 1.00 12.14  ? 23  GLY A CA    1 
ATOM   102   C  C     . GLY A 1 23  ? 237.003 211.836 194.541 1.00 12.02  ? 23  GLY A C     1 
ATOM   103   O  O     . GLY A 1 23  ? 237.512 211.305 193.564 1.00 12.38  ? 23  GLY A O     1 
ATOM   104   N  N     . LEU A 1 24  ? 237.572 211.811 195.740 1.00 12.85  ? 24  LEU A N     1 
ATOM   105   C  CA    . LEU A 1 24  ? 238.847 211.148 195.951 1.00 13.12  ? 24  LEU A CA    1 
ATOM   106   C  C     . LEU A 1 24  ? 238.714 209.643 195.739 1.00 12.55  ? 24  LEU A C     1 
ATOM   107   O  O     . LEU A 1 24  ? 239.548 209.043 195.065 1.00 11.90  ? 24  LEU A O     1 
ATOM   108   C  CB    . LEU A 1 24  ? 239.390 211.433 197.347 1.00 14.38  ? 24  LEU A CB    1 
ATOM   109   C  CG    . LEU A 1 24  ? 240.729 210.764 197.681 1.00 15.43  ? 24  LEU A CG    1 
ATOM   110   C  CD1   . LEU A 1 24  ? 241.787 211.149 196.663 1.00 15.42  ? 24  LEU A CD1   1 
ATOM   111   C  CD2   . LEU A 1 24  ? 241.165 211.147 199.076 1.00 16.70  ? 24  LEU A CD2   1 
ATOM   112   N  N     . ALA A 1 25  ? 237.654 209.033 196.286 1.00 11.44  ? 25  ALA A N     1 
ATOM   113   C  CA    . ALA A 1 25  ? 237.446 207.601 196.121 1.00 10.96  ? 25  ALA A CA    1 
ATOM   114   C  C     . ALA A 1 25  ? 237.297 207.250 194.643 1.00 10.36  ? 25  ALA A C     1 
ATOM   115   O  O     . ALA A 1 25  ? 237.778 206.220 194.198 1.00 10.77  ? 25  ALA A O     1 
ATOM   116   C  CB    . ALA A 1 25  ? 236.250 207.147 196.918 1.00 11.24  ? 25  ALA A CB    1 
ATOM   117   N  N     . THR A 1 26  ? 236.614 208.108 193.879 1.00 10.27  ? 26  THR A N     1 
ATOM   118   C  CA    . THR A 1 26  ? 236.478 207.904 192.449 1.00 10.05  ? 26  THR A CA    1 
ATOM   119   C  C     . THR A 1 26  ? 237.851 207.949 191.783 1.00 10.61  ? 26  THR A C     1 
ATOM   120   O  O     . THR A 1 26  ? 238.131 207.163 190.888 1.00 10.81  ? 26  THR A O     1 
ATOM   121   C  CB    . THR A 1 26  ? 235.534 208.941 191.843 1.00 9.93   ? 26  THR A CB    1 
ATOM   122   O  OG1   . THR A 1 26  ? 234.279 208.844 192.506 1.00 10.15  ? 26  THR A OG1   1 
ATOM   123   C  CG2   . THR A 1 26  ? 235.362 208.747 190.348 1.00 9.72   ? 26  THR A CG2   1 
ATOM   124   N  N     . ALA A 1 27  ? 238.700 208.892 192.202 1.00 11.65  ? 27  ALA A N     1 
ATOM   125   C  CA    . ALA A 1 27  ? 240.036 209.018 191.639 1.00 12.37  ? 27  ALA A CA    1 
ATOM   126   C  C     . ALA A 1 27  ? 240.876 207.780 191.934 1.00 12.90  ? 27  ALA A C     1 
ATOM   127   O  O     . ALA A 1 27  ? 241.548 207.274 191.039 1.00 12.92  ? 27  ALA A O     1 
ATOM   128   C  CB    . ALA A 1 27  ? 240.709 210.262 192.174 1.00 12.03  ? 27  ALA A CB    1 
ATOM   129   N  N     . GLU A 1 28  ? 240.832 207.293 193.171 1.00 14.88  ? 28  GLU A N     1 
ATOM   130   C  CA    . GLU A 1 28  ? 241.648 206.153 193.563 1.00 17.41  ? 28  GLU A CA    1 
ATOM   131   C  C     . GLU A 1 28  ? 241.246 204.919 192.761 1.00 16.42  ? 28  GLU A C     1 
ATOM   132   O  O     . GLU A 1 28  ? 242.104 204.168 192.306 1.00 16.28  ? 28  GLU A O     1 
ATOM   133   C  CB    . GLU A 1 28  ? 241.567 205.854 195.058 1.00 20.40  ? 28  GLU A CB    1 
ATOM   134   C  CG    . GLU A 1 28  ? 241.762 207.077 195.937 1.00 24.96  ? 28  GLU A CG    1 
ATOM   135   C  CD    . GLU A 1 28  ? 241.747 206.802 197.425 1.00 31.77  ? 28  GLU A CD    1 
ATOM   136   O  OE1   . GLU A 1 28  ? 240.892 206.036 197.918 1.00 35.95  ? 28  GLU A OE1   1 
ATOM   137   O  OE2   . GLU A 1 28  ? 242.598 207.412 198.110 1.00 35.79  ? 28  GLU A OE2   1 
ATOM   138   N  N     . ARG A 1 29  ? 239.939 204.708 192.581 1.00 15.87  ? 29  ARG A N     1 
ATOM   139   C  CA    . ARG A 1 29  ? 239.474 203.542 191.852 1.00 15.28  ? 29  ARG A CA    1 
ATOM   140   C  C     . ARG A 1 29  ? 239.861 203.632 190.380 1.00 14.60  ? 29  ARG A C     1 
ATOM   141   O  O     . ARG A 1 29  ? 240.398 202.676 189.819 1.00 15.77  ? 29  ARG A O     1 
ATOM   142   C  CB    . ARG A 1 29  ? 237.961 203.367 191.999 1.00 15.56  ? 29  ARG A CB    1 
ATOM   143   C  CG    . ARG A 1 29  ? 237.471 202.140 191.255 1.00 16.13  ? 29  ARG A CG    1 
ATOM   144   C  CD    . ARG A 1 29  ? 236.011 201.859 191.536 1.00 17.53  ? 29  ARG A CD    1 
ATOM   145   N  NE    . ARG A 1 29  ? 235.618 200.618 190.867 1.00 18.29  ? 29  ARG A NE    1 
ATOM   146   C  CZ    . ARG A 1 29  ? 235.668 199.414 191.416 1.00 20.09  ? 29  ARG A CZ    1 
ATOM   147   N  NH1   . ARG A 1 29  ? 235.969 199.258 192.692 1.00 21.12  ? 29  ARG A NH1   1 
ATOM   148   N  NH2   . ARG A 1 29  ? 235.357 198.360 190.690 1.00 21.27  ? 29  ARG A NH2   1 
ATOM   149   N  N     . LEU A 1 30  ? 239.571 204.765 189.741 1.00 15.06  ? 30  LEU A N     1 
ATOM   150   C  CA    . LEU A 1 30  ? 239.822 204.907 188.317 1.00 16.06  ? 30  LEU A CA    1 
ATOM   151   C  C     . LEU A 1 30  ? 241.316 204.807 188.022 1.00 16.46  ? 30  LEU A C     1 
ATOM   152   O  O     . LEU A 1 30  ? 241.709 204.167 187.052 1.00 17.24  ? 30  LEU A O     1 
ATOM   153   C  CB    . LEU A 1 30  ? 239.226 206.207 187.787 1.00 16.57  ? 30  LEU A CB    1 
ATOM   154   C  CG    . LEU A 1 30  ? 237.697 206.266 187.741 1.00 17.33  ? 30  LEU A CG    1 
ATOM   155   C  CD1   . LEU A 1 30  ? 237.244 207.566 187.069 1.00 16.98  ? 30  LEU A CD1   1 
ATOM   156   C  CD2   . LEU A 1 30  ? 237.093 205.046 187.035 1.00 18.10  ? 30  LEU A CD2   1 
ATOM   157   N  N     . VAL A 1 31  ? 242.148 205.450 188.838 1.00 17.05  ? 31  VAL A N     1 
ATOM   158   C  CA    . VAL A 1 31  ? 243.590 205.365 188.648 1.00 18.74  ? 31  VAL A CA    1 
ATOM   159   C  C     . VAL A 1 31  ? 244.062 203.927 188.844 1.00 19.63  ? 31  VAL A C     1 
ATOM   160   O  O     . VAL A 1 31  ? 244.880 203.423 188.083 1.00 21.55  ? 31  VAL A O     1 
ATOM   161   C  CB    . VAL A 1 31  ? 244.336 206.340 189.574 1.00 19.21  ? 31  VAL A CB    1 
ATOM   162   C  CG1   . VAL A 1 31  ? 245.822 206.025 189.633 1.00 20.45  ? 31  VAL A CG1   1 
ATOM   163   C  CG2   . VAL A 1 31  ? 244.128 207.773 189.119 1.00 19.61  ? 31  VAL A CG2   1 
ATOM   164   N  N     . GLY A 1 32  ? 243.539 203.255 189.873 1.00 21.28  ? 32  GLY A N     1 
ATOM   165   C  CA    . GLY A 1 32  ? 243.849 201.853 190.120 1.00 21.66  ? 32  GLY A CA    1 
ATOM   166   C  C     . GLY A 1 32  ? 243.431 200.936 188.971 1.00 22.82  ? 32  GLY A C     1 
ATOM   167   O  O     . GLY A 1 32  ? 244.004 199.865 188.801 1.00 24.69  ? 32  GLY A O     1 
ATOM   168   N  N     . GLN A 1 33  ? 242.419 201.344 188.198 1.00 24.18  ? 33  GLN A N     1 
ATOM   169   C  CA    . GLN A 1 33  ? 241.931 200.557 187.075 1.00 24.17  ? 33  GLN A CA    1 
ATOM   170   C  C     . GLN A 1 33  ? 242.600 200.964 185.762 1.00 23.31  ? 33  GLN A C     1 
ATOM   171   O  O     . GLN A 1 33  ? 242.221 200.462 184.710 1.00 27.00  ? 33  GLN A O     1 
ATOM   172   C  CB    . GLN A 1 33  ? 240.419 200.724 186.941 1.00 25.32  ? 33  GLN A CB    1 
ATOM   173   C  CG    . GLN A 1 33  ? 239.617 200.168 188.111 1.00 27.83  ? 33  GLN A CG    1 
ATOM   174   C  CD    . GLN A 1 33  ? 239.389 198.677 188.031 1.00 30.52  ? 33  GLN A CD    1 
ATOM   175   O  OE1   . GLN A 1 33  ? 239.015 198.128 186.985 1.00 31.53  ? 33  GLN A OE1   1 
ATOM   176   N  NE2   . GLN A 1 33  ? 239.635 198.001 189.144 1.00 33.35  ? 33  GLN A NE2   1 
ATOM   177   N  N     . GLY A 1 34  ? 243.587 201.865 185.808 1.00 21.96  ? 34  GLY A N     1 
ATOM   178   C  CA    . GLY A 1 34  ? 244.386 202.184 184.638 1.00 20.81  ? 34  GLY A CA    1 
ATOM   179   C  C     . GLY A 1 34  ? 244.018 203.516 183.985 1.00 20.55  ? 34  GLY A C     1 
ATOM   180   O  O     . GLY A 1 34  ? 244.583 203.850 182.946 1.00 20.57  ? 34  GLY A O     1 
ATOM   181   N  N     . ALA A 1 35  ? 243.090 204.280 184.574 1.00 19.64  ? 35  ALA A N     1 
ATOM   182   C  CA    . ALA A 1 35  ? 242.710 205.568 184.022 1.00 19.36  ? 35  ALA A CA    1 
ATOM   183   C  C     . ALA A 1 35  ? 243.619 206.667 184.567 1.00 19.06  ? 35  ALA A C     1 
ATOM   184   O  O     . ALA A 1 35  ? 244.360 206.472 185.531 1.00 21.13  ? 35  ALA A O     1 
ATOM   185   C  CB    . ALA A 1 35  ? 241.256 205.869 184.334 1.00 20.01  ? 35  ALA A CB    1 
ATOM   186   N  N     . SER A 1 36  ? 243.551 207.835 183.924 1.00 18.25  ? 36  SER A N     1 
ATOM   187   C  CA    . SER A 1 36  ? 244.224 209.036 184.388 1.00 18.75  ? 36  SER A CA    1 
ATOM   188   C  C     . SER A 1 36  ? 243.189 209.978 185.002 1.00 18.32  ? 36  SER A C     1 
ATOM   189   O  O     . SER A 1 36  ? 242.085 210.126 184.470 1.00 19.67  ? 36  SER A O     1 
ATOM   190   C  CB    . SER A 1 36  ? 244.972 209.710 183.269 1.00 19.72  ? 36  SER A CB    1 
ATOM   191   O  OG    . SER A 1 36  ? 245.846 208.800 182.613 1.00 21.08  ? 36  SER A OG    1 
ATOM   192   N  N     . ALA A 1 37  ? 243.558 210.613 186.117 1.00 17.85  ? 37  ALA A N     1 
ATOM   193   C  CA    . ALA A 1 37  ? 242.634 211.459 186.858 1.00 18.29  ? 37  ALA A CA    1 
ATOM   194   C  C     . ALA A 1 37  ? 243.219 212.852 187.027 1.00 18.81  ? 37  ALA A C     1 
ATOM   195   O  O     . ALA A 1 37  ? 244.419 213.016 187.235 1.00 20.80  ? 37  ALA A O     1 
ATOM   196   C  CB    . ALA A 1 37  ? 242.307 210.856 188.203 1.00 18.56  ? 37  ALA A CB    1 
ATOM   197   N  N     . VAL A 1 38  ? 242.339 213.853 186.954 1.00 18.54  ? 38  VAL A N     1 
ATOM   198   C  CA    . VAL A 1 38  ? 242.672 215.222 187.293 1.00 17.60  ? 38  VAL A CA    1 
ATOM   199   C  C     . VAL A 1 38  ? 241.810 215.637 188.473 1.00 17.92  ? 38  VAL A C     1 
ATOM   200   O  O     . VAL A 1 38  ? 240.588 215.678 188.366 1.00 19.03  ? 38  VAL A O     1 
ATOM   201   C  CB    . VAL A 1 38  ? 242.459 216.151 186.092 1.00 18.14  ? 38  VAL A CB    1 
ATOM   202   C  CG1   . VAL A 1 38  ? 242.739 217.595 186.458 1.00 17.76  ? 38  VAL A CG1   1 
ATOM   203   C  CG2   . VAL A 1 38  ? 243.310 215.705 184.915 1.00 18.48  ? 38  VAL A CG2   1 
ATOM   204   N  N     . LEU A 1 39  ? 242.453 215.942 189.600 1.00 17.94  ? 39  LEU A N     1 
ATOM   205   C  CA    . LEU A 1 39  ? 241.739 216.342 190.797 1.00 17.54  ? 39  LEU A CA    1 
ATOM   206   C  C     . LEU A 1 39  ? 241.482 217.841 190.739 1.00 18.36  ? 39  LEU A C     1 
ATOM   207   O  O     . LEU A 1 39  ? 242.394 218.645 190.929 1.00 18.64  ? 39  LEU A O     1 
ATOM   208   C  CB    . LEU A 1 39  ? 242.514 215.965 192.055 1.00 18.27  ? 39  LEU A CB    1 
ATOM   209   C  CG    . LEU A 1 39  ? 242.998 214.522 192.157 1.00 18.44  ? 39  LEU A CG    1 
ATOM   210   C  CD1   . LEU A 1 39  ? 243.608 214.287 193.535 1.00 18.55  ? 39  LEU A CD1   1 
ATOM   211   C  CD2   . LEU A 1 39  ? 241.859 213.567 191.904 1.00 18.51  ? 39  LEU A CD2   1 
ATOM   212   N  N     . LEU A 1 40  ? 240.220 218.209 190.482 1.00 18.02  ? 40  LEU A N     1 
ATOM   213   C  CA    . LEU A 1 40  ? 239.800 219.595 190.453 1.00 18.67  ? 40  LEU A CA    1 
ATOM   214   C  C     . LEU A 1 40  ? 239.182 219.919 191.811 1.00 18.52  ? 40  LEU A C     1 
ATOM   215   O  O     . LEU A 1 40  ? 238.094 219.448 192.144 1.00 19.62  ? 40  LEU A O     1 
ATOM   216   C  CB    . LEU A 1 40  ? 238.832 219.799 189.284 1.00 19.61  ? 40  LEU A CB    1 
ATOM   217   C  CG    . LEU A 1 40  ? 238.572 221.234 188.816 1.00 20.19  ? 40  LEU A CG    1 
ATOM   218   C  CD1   . LEU A 1 40  ? 238.046 221.216 187.405 1.00 19.81  ? 40  LEU A CD1   1 
ATOM   219   C  CD2   . LEU A 1 40  ? 237.586 221.965 189.699 1.00 21.72  ? 40  LEU A CD2   1 
ATOM   220   N  N     . ASP A 1 41  ? 239.900 220.724 192.598 1.00 18.50  ? 41  ASP A N     1 
ATOM   221   C  CA    . ASP A 1 41  ? 239.438 221.103 193.917 1.00 19.36  ? 41  ASP A CA    1 
ATOM   222   C  C     . ASP A 1 41  ? 240.060 222.441 194.300 1.00 19.34  ? 41  ASP A C     1 
ATOM   223   O  O     . ASP A 1 41  ? 240.912 222.964 193.589 1.00 18.79  ? 41  ASP A O     1 
ATOM   224   C  CB    . ASP A 1 41  ? 239.730 220.023 194.945 1.00 21.95  ? 41  ASP A CB    1 
ATOM   225   C  CG    . ASP A 1 41  ? 238.707 219.958 196.074 1.00 24.34  ? 41  ASP A CG    1 
ATOM   226   O  OD1   . ASP A 1 41  ? 238.094 221.014 196.378 1.00 26.93  ? 41  ASP A OD1   1 
ATOM   227   O  OD2   . ASP A 1 41  ? 238.489 218.854 196.611 1.00 24.49  ? 41  ASP A OD2   1 
ATOM   228   N  N     . LEU A 1 42  ? 239.608 222.994 195.422 1.00 19.25  ? 42  LEU A N     1 
ATOM   229   C  CA    . LEU A 1 42  ? 240.076 224.296 195.864 1.00 20.51  ? 42  LEU A CA    1 
ATOM   230   C  C     . LEU A 1 42  ? 241.559 224.238 196.204 1.00 20.75  ? 42  LEU A C     1 
ATOM   231   O  O     . LEU A 1 42  ? 242.088 223.194 196.572 1.00 20.21  ? 42  LEU A O     1 
ATOM   232   C  CB    . LEU A 1 42  ? 239.252 224.764 197.058 1.00 20.53  ? 42  LEU A CB    1 
ATOM   233   C  CG    . LEU A 1 42  ? 237.783 225.081 196.768 1.00 21.71  ? 42  LEU A CG    1 
ATOM   234   C  CD1   . LEU A 1 42  ? 237.040 225.361 198.057 1.00 22.60  ? 42  LEU A CD1   1 
ATOM   235   C  CD2   . LEU A 1 42  ? 237.648 226.258 195.836 1.00 21.96  ? 42  LEU A CD2   1 
ATOM   236   N  N     . PRO A 1 43  ? 242.279 225.374 196.089 1.00 24.21  ? 43  PRO A N     1 
ATOM   237   C  CA    . PRO A 1 43  ? 243.689 225.436 196.475 1.00 25.11  ? 43  PRO A CA    1 
ATOM   238   C  C     . PRO A 1 43  ? 243.990 224.972 197.896 1.00 26.85  ? 43  PRO A C     1 
ATOM   239   O  O     . PRO A 1 43  ? 245.066 224.437 198.135 1.00 30.59  ? 43  PRO A O     1 
ATOM   240   C  CB    . PRO A 1 43  ? 244.015 226.920 196.297 1.00 25.44  ? 43  PRO A CB    1 
ATOM   241   C  CG    . PRO A 1 43  ? 243.092 227.361 195.209 1.00 25.80  ? 43  PRO A CG    1 
ATOM   242   C  CD    . PRO A 1 43  ? 241.795 226.650 195.552 1.00 25.11  ? 43  PRO A CD    1 
ATOM   243   N  N     . ASN A 1 44  ? 243.051 225.160 198.832 1.00 29.69  ? 44  ASN A N     1 
ATOM   244   C  CA    . ASN A 1 44  ? 243.288 224.801 200.222 1.00 35.50  ? 44  ASN A CA    1 
ATOM   245   C  C     . ASN A 1 44  ? 242.861 223.365 200.549 1.00 34.42  ? 44  ASN A C     1 
ATOM   246   O  O     . ASN A 1 44  ? 242.917 222.958 201.707 1.00 35.07  ? 44  ASN A O     1 
ATOM   247   C  CB    . ASN A 1 44  ? 242.579 225.772 201.160 1.00 39.91  ? 44  ASN A CB    1 
ATOM   248   C  CG    . ASN A 1 44  ? 241.074 225.618 201.162 1.00 47.36  ? 44  ASN A CG    1 
ATOM   249   O  OD1   . ASN A 1 44  ? 240.480 224.988 200.280 1.00 47.71  ? 44  ASN A OD1   1 
ATOM   250   N  ND2   . ASN A 1 44  ? 240.430 226.160 202.183 1.00 48.62  ? 44  ASN A ND2   1 
ATOM   251   N  N     . SER A 1 45  ? 242.400 222.609 199.547 1.00 33.25  ? 45  SER A N     1 
ATOM   252   C  CA    . SER A 1 45  ? 241.791 221.303 199.787 1.00 31.82  ? 45  SER A CA    1 
ATOM   253   C  C     . SER A 1 45  ? 242.819 220.222 200.112 1.00 30.89  ? 45  SER A C     1 
ATOM   254   O  O     . SER A 1 45  ? 242.443 219.149 200.574 1.00 31.68  ? 45  SER A O     1 
ATOM   255   C  CB    . SER A 1 45  ? 240.953 220.870 198.617 1.00 31.16  ? 45  SER A CB    1 
ATOM   256   O  OG    . SER A 1 45  ? 241.744 220.802 197.444 1.00 29.05  ? 45  SER A OG    1 
ATOM   257   N  N     . GLY A 1 46  ? 244.100 220.470 199.846 1.00 29.59  ? 46  GLY A N     1 
ATOM   258   C  CA    . GLY A 1 46  ? 245.103 219.438 200.038 1.00 29.05  ? 46  GLY A CA    1 
ATOM   259   C  C     . GLY A 1 46  ? 245.153 218.449 198.873 1.00 27.26  ? 46  GLY A C     1 
ATOM   260   O  O     . GLY A 1 46  ? 245.650 217.349 199.040 1.00 28.04  ? 46  GLY A O     1 
ATOM   261   N  N     . GLY A 1 47  ? 244.684 218.856 197.693 1.00 26.61  ? 47  GLY A N     1 
ATOM   262   C  CA    . GLY A 1 47  ? 244.650 217.978 196.537 1.00 26.04  ? 47  GLY A CA    1 
ATOM   263   C  C     . GLY A 1 47  ? 246.031 217.632 195.996 1.00 25.27  ? 47  GLY A C     1 
ATOM   264   O  O     . GLY A 1 47  ? 246.193 216.588 195.370 1.00 24.83  ? 47  GLY A O     1 
ATOM   265   N  N     . GLU A 1 48  ? 247.022 218.502 196.223 1.00 25.67  ? 48  GLU A N     1 
ATOM   266   C  CA    . GLU A 1 48  ? 248.374 218.235 195.755 1.00 27.74  ? 48  GLU A CA    1 
ATOM   267   C  C     . GLU A 1 48  ? 248.935 216.968 196.404 1.00 25.16  ? 48  GLU A C     1 
ATOM   268   O  O     . GLU A 1 48  ? 249.574 216.161 195.737 1.00 26.39  ? 48  GLU A O     1 
ATOM   269   C  CB    . GLU A 1 48  ? 249.271 219.443 196.033 1.00 33.38  ? 48  GLU A CB    1 
ATOM   270   C  CG    . GLU A 1 48  ? 250.702 219.271 195.537 1.00 37.95  ? 48  GLU A CG    1 
ATOM   271   C  CD    . GLU A 1 48  ? 250.840 219.101 194.036 1.00 45.87  ? 48  GLU A CD    1 
ATOM   272   O  OE1   . GLU A 1 48  ? 249.960 219.560 193.268 1.00 50.89  ? 48  GLU A OE1   1 
ATOM   273   O  OE2   . GLU A 1 48  ? 251.852 218.486 193.634 1.00 50.48  ? 48  GLU A OE2   1 
ATOM   274   N  N     . ALA A 1 49  ? 248.712 216.795 197.710 1.00 24.50  ? 49  ALA A N     1 
ATOM   275   C  CA    . ALA A 1 49  ? 249.199 215.610 198.405 1.00 24.00  ? 49  ALA A CA    1 
ATOM   276   C  C     . ALA A 1 49  ? 248.489 214.354 197.900 1.00 23.43  ? 49  ALA A C     1 
ATOM   277   O  O     . ALA A 1 49  ? 249.116 213.313 197.717 1.00 23.86  ? 49  ALA A O     1 
ATOM   278   C  CB    . ALA A 1 49  ? 249.024 215.772 199.895 1.00 24.72  ? 49  ALA A CB    1 
ATOM   279   N  N     . GLN A 1 50  ? 247.180 214.448 197.656 1.00 22.71  ? 50  GLN A N     1 
ATOM   280   C  CA    . GLN A 1 50  ? 246.428 213.309 197.158 1.00 21.96  ? 50  GLN A CA    1 
ATOM   281   C  C     . GLN A 1 50  ? 246.891 212.925 195.756 1.00 21.02  ? 50  GLN A C     1 
ATOM   282   O  O     . GLN A 1 50  ? 247.036 211.740 195.451 1.00 21.61  ? 50  GLN A O     1 
ATOM   283   C  CB    . GLN A 1 50  ? 244.931 213.612 197.165 1.00 23.00  ? 50  GLN A CB    1 
ATOM   284   C  CG    . GLN A 1 50  ? 244.352 213.865 198.549 1.00 24.07  ? 50  GLN A CG    1 
ATOM   285   C  CD    . GLN A 1 50  ? 244.658 212.765 199.538 1.00 25.83  ? 50  GLN A CD    1 
ATOM   286   O  OE1   . GLN A 1 50  ? 244.653 211.570 199.216 1.00 26.44  ? 50  GLN A OE1   1 
ATOM   287   N  NE2   . GLN A 1 50  ? 244.919 213.164 200.774 1.00 29.35  ? 50  GLN A NE2   1 
ATOM   288   N  N     . ALA A 1 51  ? 247.120 213.925 194.895 1.00 21.77  ? 51  ALA A N     1 
ATOM   289   C  CA    . ALA A 1 51  ? 247.556 213.657 193.537 1.00 23.08  ? 51  ALA A CA    1 
ATOM   290   C  C     . ALA A 1 51  ? 248.925 212.979 193.528 1.00 26.18  ? 51  ALA A C     1 
ATOM   291   O  O     . ALA A 1 51  ? 249.160 212.064 192.739 1.00 28.44  ? 51  ALA A O     1 
ATOM   292   C  CB    . ALA A 1 51  ? 247.567 214.924 192.719 1.00 23.07  ? 51  ALA A CB    1 
ATOM   293   N  N     . LYS A 1 52  ? 249.834 213.441 194.391 1.00 29.46  ? 52  LYS A N     1 
ATOM   294   C  CA    . LYS A 1 52  ? 251.150 212.826 194.497 1.00 32.34  ? 52  LYS A CA    1 
ATOM   295   C  C     . LYS A 1 52  ? 251.026 211.390 195.005 1.00 30.61  ? 52  LYS A C     1 
ATOM   296   O  O     . LYS A 1 52  ? 251.750 210.507 194.556 1.00 31.90  ? 52  LYS A O     1 
ATOM   297   C  CB    . LYS A 1 52  ? 252.056 213.650 195.413 1.00 36.45  ? 52  LYS A CB    1 
ATOM   298   C  CG    . LYS A 1 52  ? 253.461 213.101 195.539 1.00 43.43  ? 52  LYS A CG    1 
ATOM   299   C  CD    . LYS A 1 52  ? 254.400 214.032 196.293 1.00 49.63  ? 52  LYS A CD    1 
ATOM   300   C  CE    . LYS A 1 52  ? 255.806 213.520 196.297 1.00 53.79  ? 52  LYS A CE    1 
ATOM   301   N  NZ    . LYS A 1 52  ? 255.933 212.223 196.974 1.00 56.08  ? 52  LYS A NZ    1 
ATOM   302   N  N     . LYS A 1 53  ? 250.113 211.155 195.948 1.00 29.30  ? 53  LYS A N     1 
ATOM   303   C  CA    . LYS A 1 53  ? 249.923 209.821 196.497 1.00 30.79  ? 53  LYS A CA    1 
ATOM   304   C  C     . LYS A 1 53  ? 249.416 208.854 195.424 1.00 30.87  ? 53  LYS A C     1 
ATOM   305   O  O     . LYS A 1 53  ? 249.803 207.690 195.409 1.00 31.31  ? 53  LYS A O     1 
ATOM   306   C  CB    . LYS A 1 53  ? 248.966 209.891 197.687 1.00 32.71  ? 53  LYS A CB    1 
ATOM   307   C  CG    . LYS A 1 53  ? 248.480 208.576 198.223 1.00 37.73  ? 53  LYS A CG    1 
ATOM   308   C  CD    . LYS A 1 53  ? 247.755 208.728 199.555 1.00 42.11  ? 53  LYS A CD    1 
ATOM   309   C  CE    . LYS A 1 53  ? 246.960 207.493 199.856 1.00 46.35  ? 53  LYS A CE    1 
ATOM   310   N  NZ    . LYS A 1 53  ? 246.392 207.477 201.209 1.00 48.99  ? 53  LYS A NZ    1 
ATOM   311   N  N     . LEU A 1 54  ? 248.544 209.332 194.533 1.00 30.16  ? 54  LEU A N     1 
ATOM   312   C  CA    . LEU A 1 54  ? 247.943 208.466 193.531 1.00 29.55  ? 54  LEU A CA    1 
ATOM   313   C  C     . LEU A 1 54  ? 248.897 208.119 192.391 1.00 28.61  ? 54  LEU A C     1 
ATOM   314   O  O     . LEU A 1 54  ? 248.617 207.168 191.668 1.00 30.14  ? 54  LEU A O     1 
ATOM   315   C  CB    . LEU A 1 54  ? 246.662 209.090 192.993 1.00 29.75  ? 54  LEU A CB    1 
ATOM   316   C  CG    . LEU A 1 54  ? 245.419 208.873 193.855 1.00 29.95  ? 54  LEU A CG    1 
ATOM   317   C  CD1   . LEU A 1 54  ? 244.209 209.560 193.249 1.00 30.98  ? 54  LEU A CD1   1 
ATOM   318   C  CD2   . LEU A 1 54  ? 245.167 207.381 193.985 1.00 32.05  ? 54  LEU A CD2   1 
ATOM   319   N  N     . GLY A 1 55  ? 249.996 208.864 192.239 1.00 29.10  ? 55  GLY A N     1 
ATOM   320   C  CA    . GLY A 1 55  ? 251.026 208.516 191.272 1.00 27.53  ? 55  GLY A CA    1 
ATOM   321   C  C     . GLY A 1 55  ? 251.065 209.474 190.087 1.00 29.84  ? 55  GLY A C     1 
ATOM   322   O  O     . GLY A 1 55  ? 250.472 210.548 190.109 1.00 33.21  ? 55  GLY A O     1 
ATOM   323   N  N     . ASN A 1 56  ? 251.771 209.057 189.036 1.00 30.41  ? 56  ASN A N     1 
ATOM   324   C  CA    . ASN A 1 56  ? 252.044 209.906 187.891 1.00 32.89  ? 56  ASN A CA    1 
ATOM   325   C  C     . ASN A 1 56  ? 250.814 210.069 186.996 1.00 30.80  ? 56  ASN A C     1 
ATOM   326   O  O     . ASN A 1 56  ? 250.787 210.961 186.149 1.00 29.56  ? 56  ASN A O     1 
ATOM   327   C  CB    . ASN A 1 56  ? 253.225 209.370 187.089 1.00 38.48  ? 56  ASN A CB    1 
ATOM   328   C  CG    . ASN A 1 56  ? 254.543 209.644 187.779 1.00 45.20  ? 56  ASN A CG    1 
ATOM   329   O  OD1   . ASN A 1 56  ? 254.705 210.701 188.402 1.00 46.08  ? 56  ASN A OD1   1 
ATOM   330   N  ND2   . ASN A 1 56  ? 255.504 208.734 187.664 1.00 48.44  ? 56  ASN A ND2   1 
ATOM   331   N  N     . ASN A 1 57  ? 249.824 209.182 187.139 1.00 30.24  ? 57  ASN A N     1 
ATOM   332   C  CA    . ASN A 1 57  ? 248.617 209.268 186.330 1.00 29.24  ? 57  ASN A CA    1 
ATOM   333   C  C     . ASN A 1 57  ? 247.564 210.166 186.975 1.00 26.49  ? 57  ASN A C     1 
ATOM   334   O  O     . ASN A 1 57  ? 246.456 210.253 186.451 1.00 25.38  ? 57  ASN A O     1 
ATOM   335   C  CB    . ASN A 1 57  ? 248.024 207.892 186.055 1.00 31.62  ? 57  ASN A CB    1 
ATOM   336   C  CG    . ASN A 1 57  ? 248.853 207.094 185.076 1.00 34.47  ? 57  ASN A CG    1 
ATOM   337   O  OD1   . ASN A 1 57  ? 249.352 206.018 185.424 1.00 36.31  ? 57  ASN A OD1   1 
ATOM   338   N  ND2   . ASN A 1 57  ? 248.992 207.571 183.846 1.00 36.77  ? 57  ASN A ND2   1 
ATOM   339   N  N     . CYS A 1 58  ? 247.907 210.851 188.073 1.00 25.13  ? 58  CYS A N     1 
ATOM   340   C  CA    . CYS A 1 58  ? 247.002 211.769 188.738 1.00 24.40  ? 58  CYS A CA    1 
ATOM   341   C  C     . CYS A 1 58  ? 247.699 213.110 188.956 1.00 25.06  ? 58  CYS A C     1 
ATOM   342   O  O     . CYS A 1 58  ? 248.842 213.148 189.409 1.00 26.41  ? 58  CYS A O     1 
ATOM   343   C  CB    . CYS A 1 58  ? 246.540 211.188 190.064 1.00 24.37  ? 58  CYS A CB    1 
ATOM   344   S  SG    . CYS A 1 58  ? 245.176 212.105 190.826 1.00 25.35  ? 58  CYS A SG    1 
ATOM   345   N  N     . VAL A 1 59  ? 246.996 214.197 188.628 1.00 24.09  ? 59  VAL A N     1 
ATOM   346   C  CA    . VAL A 1 59  ? 247.491 215.537 188.868 1.00 23.76  ? 59  VAL A CA    1 
ATOM   347   C  C     . VAL A 1 59  ? 246.410 216.350 189.561 1.00 22.29  ? 59  VAL A C     1 
ATOM   348   O  O     . VAL A 1 59  ? 245.221 216.091 189.411 1.00 22.83  ? 59  VAL A O     1 
ATOM   349   C  CB    . VAL A 1 59  ? 247.967 216.246 187.591 1.00 25.42  ? 59  VAL A CB    1 
ATOM   350   C  CG1   . VAL A 1 59  ? 249.203 215.561 187.029 1.00 26.87  ? 59  VAL A CG1   1 
ATOM   351   C  CG2   . VAL A 1 59  ? 246.847 216.369 186.571 1.00 26.69  ? 59  VAL A CG2   1 
ATOM   352   N  N     . PHE A 1 60  ? 246.859 217.367 190.298 1.00 21.78  ? 60  PHE A N     1 
ATOM   353   C  CA    . PHE A 1 60  ? 245.981 218.275 190.993 1.00 21.42  ? 60  PHE A CA    1 
ATOM   354   C  C     . PHE A 1 60  ? 245.824 219.558 190.182 1.00 21.34  ? 60  PHE A C     1 
ATOM   355   O  O     . PHE A 1 60  ? 246.806 220.185 189.812 1.00 23.47  ? 60  PHE A O     1 
ATOM   356   C  CB    . PHE A 1 60  ? 246.540 218.571 192.378 1.00 21.43  ? 60  PHE A CB    1 
ATOM   357   C  CG    . PHE A 1 60  ? 245.785 219.659 193.106 1.00 22.73  ? 60  PHE A CG    1 
ATOM   358   C  CD1   . PHE A 1 60  ? 244.409 219.578 193.274 1.00 23.91  ? 60  PHE A CD1   1 
ATOM   359   C  CD2   . PHE A 1 60  ? 246.460 220.759 193.612 1.00 23.79  ? 60  PHE A CD2   1 
ATOM   360   C  CE1   . PHE A 1 60  ? 243.726 220.579 193.935 1.00 24.39  ? 60  PHE A CE1   1 
ATOM   361   C  CE2   . PHE A 1 60  ? 245.771 221.759 194.279 1.00 24.45  ? 60  PHE A CE2   1 
ATOM   362   C  CZ    . PHE A 1 60  ? 244.405 221.663 194.440 1.00 25.05  ? 60  PHE A CZ    1 
ATOM   363   N  N     . ALA A 1 61  ? 244.568 219.937 189.925 1.00 19.99  ? 61  ALA A N     1 
ATOM   364   C  CA    . ALA A 1 61  ? 244.242 221.171 189.238 1.00 19.86  ? 61  ALA A CA    1 
ATOM   365   C  C     . ALA A 1 61  ? 243.463 222.064 190.192 1.00 20.50  ? 61  ALA A C     1 
ATOM   366   O  O     . ALA A 1 61  ? 242.272 221.854 190.396 1.00 21.95  ? 61  ALA A O     1 
ATOM   367   C  CB    . ALA A 1 61  ? 243.453 220.909 187.980 1.00 19.75  ? 61  ALA A CB    1 
ATOM   368   N  N     . PRO A 1 62  ? 244.099 223.085 190.800 1.00 21.58  ? 62  PRO A N     1 
ATOM   369   C  CA    . PRO A 1 62  ? 243.390 223.953 191.734 1.00 22.03  ? 62  PRO A CA    1 
ATOM   370   C  C     . PRO A 1 62  ? 242.388 224.810 190.966 1.00 21.61  ? 62  PRO A C     1 
ATOM   371   O  O     . PRO A 1 62  ? 242.747 225.490 190.003 1.00 22.56  ? 62  PRO A O     1 
ATOM   372   C  CB    . PRO A 1 62  ? 244.482 224.796 192.403 1.00 23.04  ? 62  PRO A CB    1 
ATOM   373   C  CG    . PRO A 1 62  ? 245.738 224.528 191.611 1.00 23.26  ? 62  PRO A CG    1 
ATOM   374   C  CD    . PRO A 1 62  ? 245.470 223.533 190.508 1.00 22.50  ? 62  PRO A CD    1 
ATOM   375   N  N     . ALA A 1 63  ? 241.130 224.785 191.406 1.00 20.87  ? 63  ALA A N     1 
ATOM   376   C  CA    . ALA A 1 63  ? 240.098 225.569 190.758 1.00 20.40  ? 63  ALA A CA    1 
ATOM   377   C  C     . ALA A 1 63  ? 238.896 225.693 191.682 1.00 20.12  ? 63  ALA A C     1 
ATOM   378   O  O     . ALA A 1 63  ? 238.637 224.822 192.499 1.00 20.20  ? 63  ALA A O     1 
ATOM   379   C  CB    . ALA A 1 63  ? 239.705 224.947 189.429 1.00 20.47  ? 63  ALA A CB    1 
ATOM   380   N  N     . ASP A 1 64  ? 238.157 226.785 191.499 1.00 21.05  ? 64  ASP A N     1 
ATOM   381   C  CA    . ASP A 1 64  ? 236.829 226.948 192.052 1.00 22.46  ? 64  ASP A CA    1 
ATOM   382   C  C     . ASP A 1 64  ? 235.815 226.694 190.940 1.00 19.08  ? 64  ASP A C     1 
ATOM   383   O  O     . ASP A 1 64  ? 235.859 227.348 189.898 1.00 18.76  ? 64  ASP A O     1 
ATOM   384   C  CB    . ASP A 1 64  ? 236.675 228.340 192.626 1.00 25.67  ? 64  ASP A CB    1 
ATOM   385   C  CG    . ASP A 1 64  ? 235.384 228.563 193.395 1.00 30.07  ? 64  ASP A CG    1 
ATOM   386   O  OD1   . ASP A 1 64  ? 234.479 227.703 193.324 1.00 34.39  ? 64  ASP A OD1   1 
ATOM   387   O  OD2   . ASP A 1 64  ? 235.301 229.595 194.085 1.00 33.54  ? 64  ASP A OD2   1 
ATOM   388   N  N     . VAL A 1 65  ? 234.902 225.746 191.166 1.00 17.37  ? 65  VAL A N     1 
ATOM   389   C  CA    . VAL A 1 65  ? 233.958 225.350 190.133 1.00 16.32  ? 65  VAL A CA    1 
ATOM   390   C  C     . VAL A 1 65  ? 232.993 226.484 189.791 1.00 16.15  ? 65  VAL A C     1 
ATOM   391   O  O     . VAL A 1 65  ? 232.457 226.518 188.688 1.00 15.91  ? 65  VAL A O     1 
ATOM   392   C  CB    . VAL A 1 65  ? 233.176 224.093 190.542 1.00 15.78  ? 65  VAL A CB    1 
ATOM   393   C  CG1   . VAL A 1 65  ? 234.093 222.900 190.570 1.00 15.74  ? 65  VAL A CG1   1 
ATOM   394   C  CG2   . VAL A 1 65  ? 232.467 224.253 191.874 1.00 14.65  ? 65  VAL A CG2   1 
ATOM   395   N  N     . THR A 1 66  ? 232.783 227.414 190.724 1.00 17.82  ? 66  THR A N     1 
ATOM   396   C  CA    . THR A 1 66  ? 231.919 228.564 190.465 1.00 19.62  ? 66  THR A CA    1 
ATOM   397   C  C     . THR A 1 66  ? 232.558 229.556 189.493 1.00 20.63  ? 66  THR A C     1 
ATOM   398   O  O     . THR A 1 66  ? 231.867 230.442 189.003 1.00 23.52  ? 66  THR A O     1 
ATOM   399   C  CB    . THR A 1 66  ? 231.556 229.263 191.765 1.00 20.17  ? 66  THR A CB    1 
ATOM   400   O  OG1   . THR A 1 66  ? 232.740 229.812 192.335 1.00 20.15  ? 66  THR A OG1   1 
ATOM   401   C  CG2   . THR A 1 66  ? 230.923 228.302 192.751 1.00 21.37  ? 66  THR A CG2   1 
ATOM   402   N  N     . SER A 1 67  ? 233.860 229.412 189.220 1.00 20.27  ? 67  SER A N     1 
ATOM   403   C  CA    . SER A 1 67  ? 234.587 230.345 188.376 1.00 21.38  ? 67  SER A CA    1 
ATOM   404   C  C     . SER A 1 67  ? 234.817 229.732 187.002 1.00 21.56  ? 67  SER A C     1 
ATOM   405   O  O     . SER A 1 67  ? 235.399 228.669 186.902 1.00 21.11  ? 67  SER A O     1 
ATOM   406   C  CB    . SER A 1 67  ? 235.895 230.735 189.027 1.00 21.11  ? 67  SER A CB    1 
ATOM   407   O  OG    . SER A 1 67  ? 236.807 231.302 188.097 1.00 22.08  ? 67  SER A OG    1 
ATOM   408   N  N     . GLU A 1 68  ? 234.385 230.435 185.954 1.00 24.53  ? 68  GLU A N     1 
ATOM   409   C  CA    . GLU A 1 68  ? 234.625 229.993 184.590 1.00 26.90  ? 68  GLU A CA    1 
ATOM   410   C  C     . GLU A 1 68  ? 236.127 229.967 184.300 1.00 26.53  ? 68  GLU A C     1 
ATOM   411   O  O     . GLU A 1 68  ? 236.618 229.037 183.672 1.00 25.90  ? 68  GLU A O     1 
ATOM   412   C  CB    . GLU A 1 68  ? 233.878 230.893 183.612 1.00 29.41  ? 68  GLU A CB    1 
ATOM   413   C  CG    . GLU A 1 68  ? 234.327 230.755 182.161 1.00 33.47  ? 68  GLU A CG    1 
ATOM   414   C  CD    . GLU A 1 68  ? 233.501 231.636 181.229 1.00 39.24  ? 68  GLU A CD    1 
ATOM   415   O  OE1   . GLU A 1 68  ? 233.798 232.854 181.113 1.00 42.47  ? 68  GLU A OE1   1 
ATOM   416   O  OE2   . GLU A 1 68  ? 232.542 231.118 180.621 1.00 39.74  ? 68  GLU A OE2   1 
ATOM   417   N  N     . LYS A 1 69  ? 236.856 230.992 184.738 1.00 26.37  ? 69  LYS A N     1 
ATOM   418   C  CA    . LYS A 1 69  ? 238.287 231.061 184.487 1.00 28.47  ? 69  LYS A CA    1 
ATOM   419   C  C     . LYS A 1 69  ? 239.031 229.928 185.196 1.00 24.85  ? 69  LYS A C     1 
ATOM   420   O  O     . LYS A 1 69  ? 239.947 229.342 184.621 1.00 25.67  ? 69  LYS A O     1 
ATOM   421   C  CB    . LYS A 1 69  ? 238.831 232.427 184.915 1.00 33.69  ? 69  LYS A CB    1 
ATOM   422   C  CG    . LYS A 1 69  ? 240.343 232.584 184.859 1.00 40.92  ? 69  LYS A CG    1 
ATOM   423   C  CD    . LYS A 1 69  ? 240.957 232.164 183.526 1.00 47.74  ? 69  LYS A CD    1 
ATOM   424   C  CE    . LYS A 1 69  ? 240.388 232.915 182.348 1.00 55.09  ? 69  LYS A CE    1 
ATOM   425   N  NZ    . LYS A 1 69  ? 240.524 232.161 181.095 1.00 56.80  ? 69  LYS A NZ    1 
ATOM   426   N  N     . ASP A 1 70  ? 238.666 229.636 186.447 1.00 23.10  ? 70  ASP A N     1 
ATOM   427   C  CA    . ASP A 1 70  ? 239.318 228.571 187.196 1.00 22.30  ? 70  ASP A CA    1 
ATOM   428   C  C     . ASP A 1 70  ? 239.147 227.220 186.501 1.00 20.40  ? 70  ASP A C     1 
ATOM   429   O  O     . ASP A 1 70  ? 240.103 226.460 186.358 1.00 19.89  ? 70  ASP A O     1 
ATOM   430   C  CB    . ASP A 1 70  ? 238.813 228.518 188.624 1.00 25.87  ? 70  ASP A CB    1 
ATOM   431   C  CG    . ASP A 1 70  ? 239.538 229.459 189.571 1.00 31.39  ? 70  ASP A CG    1 
ATOM   432   O  OD1   . ASP A 1 70  ? 239.449 229.231 190.804 1.00 34.06  ? 70  ASP A OD1   1 
ATOM   433   O  OD2   . ASP A 1 70  ? 240.185 230.415 189.075 1.00 33.25  ? 70  ASP A OD2   1 
ATOM   434   N  N     . VAL A 1 71  ? 237.923 226.917 186.065 1.00 18.12  ? 71  VAL A N     1 
ATOM   435   C  CA    . VAL A 1 71  ? 237.656 225.643 185.419 1.00 17.30  ? 71  VAL A CA    1 
ATOM   436   C  C     . VAL A 1 71  ? 238.365 225.582 184.071 1.00 17.38  ? 71  VAL A C     1 
ATOM   437   O  O     . VAL A 1 71  ? 238.887 224.538 183.694 1.00 17.54  ? 71  VAL A O     1 
ATOM   438   C  CB    . VAL A 1 71  ? 236.140 225.408 185.280 1.00 17.36  ? 71  VAL A CB    1 
ATOM   439   C  CG1   . VAL A 1 71  ? 235.836 224.144 184.486 1.00 18.13  ? 71  VAL A CG1   1 
ATOM   440   C  CG2   . VAL A 1 71  ? 235.479 225.346 186.650 1.00 17.52  ? 71  VAL A CG2   1 
ATOM   441   N  N     . GLN A 1 72  ? 238.383 226.694 183.337 1.00 19.19  ? 72  GLN A N     1 
ATOM   442   C  CA    . GLN A 1 72  ? 239.077 226.745 182.059 1.00 20.99  ? 72  GLN A CA    1 
ATOM   443   C  C     . GLN A 1 72  ? 240.563 226.450 182.242 1.00 20.82  ? 72  GLN A C     1 
ATOM   444   O  O     . GLN A 1 72  ? 241.153 225.726 181.441 1.00 22.24  ? 72  GLN A O     1 
ATOM   445   C  CB    . GLN A 1 72  ? 238.868 228.095 181.374 1.00 23.76  ? 72  GLN A CB    1 
ATOM   446   C  CG    . GLN A 1 72  ? 237.511 228.213 180.689 1.00 25.90  ? 72  GLN A CG    1 
ATOM   447   C  CD    . GLN A 1 72  ? 237.264 229.584 180.097 1.00 29.37  ? 72  GLN A CD    1 
ATOM   448   O  OE1   . GLN A 1 72  ? 237.625 230.604 180.689 1.00 29.95  ? 72  GLN A OE1   1 
ATOM   449   N  NE2   . GLN A 1 72  ? 236.652 229.625 178.919 1.00 30.68  ? 72  GLN A NE2   1 
ATOM   450   N  N     . THR A 1 73  ? 241.171 227.017 183.287 1.00 21.77  ? 73  THR A N     1 
ATOM   451   C  CA    . THR A 1 73  ? 242.573 226.752 183.584 1.00 22.91  ? 73  THR A CA    1 
ATOM   452   C  C     . THR A 1 73  ? 242.781 225.273 183.919 1.00 22.11  ? 73  THR A C     1 
ATOM   453   O  O     . THR A 1 73  ? 243.746 224.669 183.464 1.00 22.40  ? 73  THR A O     1 
ATOM   454   C  CB    . THR A 1 73  ? 243.051 227.639 184.734 1.00 25.06  ? 73  THR A CB    1 
ATOM   455   O  OG1   . THR A 1 73  ? 242.833 229.000 184.367 1.00 25.95  ? 73  THR A OG1   1 
ATOM   456   C  CG2   . THR A 1 73  ? 244.515 227.405 185.056 1.00 26.13  ? 73  THR A CG2   1 
ATOM   457   N  N     . ALA A 1 74  ? 241.875 224.690 184.716 1.00 21.64  ? 74  ALA A N     1 
ATOM   458   C  CA    . ALA A 1 74  ? 241.992 223.290 185.097 1.00 21.38  ? 74  ALA A CA    1 
ATOM   459   C  C     . ALA A 1 74  ? 241.876 222.378 183.876 1.00 20.29  ? 74  ALA A C     1 
ATOM   460   O  O     . ALA A 1 74  ? 242.635 221.421 183.746 1.00 21.78  ? 74  ALA A O     1 
ATOM   461   C  CB    . ALA A 1 74  ? 240.954 222.943 186.142 1.00 21.89  ? 74  ALA A CB    1 
ATOM   462   N  N     . LEU A 1 75  ? 240.933 222.667 182.977 1.00 19.76  ? 75  LEU A N     1 
ATOM   463   C  CA    . LEU A 1 75  ? 240.759 221.840 181.793 1.00 20.91  ? 75  LEU A CA    1 
ATOM   464   C  C     . LEU A 1 75  ? 241.950 221.981 180.853 1.00 21.09  ? 75  LEU A C     1 
ATOM   465   O  O     . LEU A 1 75  ? 242.328 221.019 180.185 1.00 22.18  ? 75  LEU A O     1 
ATOM   466   C  CB    . LEU A 1 75  ? 239.450 222.166 181.077 1.00 21.25  ? 75  LEU A CB    1 
ATOM   467   C  CG    . LEU A 1 75  ? 238.178 221.900 181.889 1.00 21.14  ? 75  LEU A CG    1 
ATOM   468   C  CD1   . LEU A 1 75  ? 236.950 222.307 181.118 1.00 20.98  ? 75  LEU A CD1   1 
ATOM   469   C  CD2   . LEU A 1 75  ? 238.106 220.455 182.306 1.00 21.04  ? 75  LEU A CD2   1 
ATOM   470   N  N     . ALA A 1 76  ? 242.538 223.181 180.786 1.00 22.81  ? 76  ALA A N     1 
ATOM   471   C  CA    . ALA A 1 76  ? 243.755 223.374 180.008 1.00 24.22  ? 76  ALA A CA    1 
ATOM   472   C  C     . ALA A 1 76  ? 244.894 222.543 180.596 1.00 25.82  ? 76  ALA A C     1 
ATOM   473   O  O     . ALA A 1 76  ? 245.682 221.954 179.857 1.00 26.84  ? 76  ALA A O     1 
ATOM   474   C  CB    . ALA A 1 76  ? 244.112 224.838 179.946 1.00 24.69  ? 76  ALA A CB    1 
ATOM   475   N  N     . LEU A 1 77  ? 244.977 222.493 181.929 1.00 26.58  ? 77  LEU A N     1 
ATOM   476   C  CA    . LEU A 1 77  ? 245.979 221.675 182.598 1.00 28.37  ? 77  LEU A CA    1 
ATOM   477   C  C     . LEU A 1 77  ? 245.743 220.201 182.290 1.00 28.27  ? 77  LEU A C     1 
ATOM   478   O  O     . LEU A 1 77  ? 246.696 219.466 182.040 1.00 28.57  ? 77  LEU A O     1 
ATOM   479   C  CB    . LEU A 1 77  ? 245.946 221.961 184.102 1.00 31.19  ? 77  LEU A CB    1 
ATOM   480   C  CG    . LEU A 1 77  ? 247.008 221.310 184.989 1.00 33.65  ? 77  LEU A CG    1 
ATOM   481   C  CD1   . LEU A 1 77  ? 247.297 222.206 186.181 1.00 36.19  ? 77  LEU A CD1   1 
ATOM   482   C  CD2   . LEU A 1 77  ? 246.554 219.964 185.497 1.00 35.39  ? 77  LEU A CD2   1 
ATOM   483   N  N     . ALA A 1 78  ? 244.474 219.767 182.320 1.00 28.13  ? 78  ALA A N     1 
ATOM   484   C  CA    . ALA A 1 78  ? 244.142 218.379 182.037 1.00 28.19  ? 78  ALA A CA    1 
ATOM   485   C  C     . ALA A 1 78  ? 244.533 218.018 180.608 1.00 27.87  ? 78  ALA A C     1 
ATOM   486   O  O     . ALA A 1 78  ? 245.115 216.964 180.367 1.00 28.28  ? 78  ALA A O     1 
ATOM   487   C  CB    . ALA A 1 78  ? 242.664 218.119 182.278 1.00 29.09  ? 78  ALA A CB    1 
ATOM   488   N  N     . LYS A 1 79  ? 244.199 218.891 179.659 1.00 29.30  ? 79  LYS A N     1 
ATOM   489   C  CA    . LYS A 1 79  ? 244.525 218.649 178.267 1.00 31.75  ? 79  LYS A CA    1 
ATOM   490   C  C     . LYS A 1 79  ? 246.040 218.667 178.061 1.00 31.56  ? 79  LYS A C     1 
ATOM   491   O  O     . LYS A 1 79  ? 246.577 217.868 177.298 1.00 29.10  ? 79  LYS A O     1 
ATOM   492   C  CB    . LYS A 1 79  ? 243.839 219.679 177.368 1.00 36.37  ? 79  LYS A CB    1 
ATOM   493   C  CG    . LYS A 1 79  ? 244.019 219.414 175.891 1.00 42.24  ? 79  LYS A CG    1 
ATOM   494   C  CD    . LYS A 1 79  ? 243.214 220.387 175.040 1.00 48.58  ? 79  LYS A CD    1 
ATOM   495   C  CE    . LYS A 1 79  ? 243.435 220.184 173.576 1.00 52.98  ? 79  LYS A CE    1 
ATOM   496   N  NZ    . LYS A 1 79  ? 242.610 221.095 172.773 1.00 55.92  ? 79  LYS A NZ    1 
ATOM   497   N  N     . GLY A 1 80  ? 246.729 219.594 178.723 1.00 30.28  ? 80  GLY A N     1 
ATOM   498   C  CA    . GLY A 1 80  ? 248.169 219.711 178.585 1.00 30.68  ? 80  GLY A CA    1 
ATOM   499   C  C     . GLY A 1 80  ? 248.901 218.461 179.070 1.00 31.55  ? 80  GLY A C     1 
ATOM   500   O  O     . GLY A 1 80  ? 249.864 218.031 178.440 1.00 31.10  ? 80  GLY A O     1 
ATOM   501   N  N     . LYS A 1 81  ? 248.453 217.890 180.192 1.00 30.37  ? 81  LYS A N     1 
ATOM   502   C  CA    . LYS A 1 81  ? 249.152 216.752 180.761 1.00 29.52  ? 81  LYS A CA    1 
ATOM   503   C  C     . LYS A 1 81  ? 248.760 215.447 180.070 1.00 27.85  ? 81  LYS A C     1 
ATOM   504   O  O     . LYS A 1 81  ? 249.618 214.616 179.785 1.00 26.69  ? 81  LYS A O     1 
ATOM   505   C  CB    . LYS A 1 81  ? 248.885 216.672 182.263 1.00 32.87  ? 81  LYS A CB    1 
ATOM   506   C  CG    . LYS A 1 81  ? 249.352 215.392 182.906 1.00 36.23  ? 81  LYS A CG    1 
ATOM   507   C  CD    . LYS A 1 81  ? 250.830 215.319 183.260 1.00 39.61  ? 81  LYS A CD    1 
ATOM   508   C  CE    . LYS A 1 81  ? 251.059 214.256 184.296 1.00 43.64  ? 81  LYS A CE    1 
ATOM   509   N  NZ    . LYS A 1 81  ? 252.472 213.926 184.489 1.00 46.45  ? 81  LYS A NZ    1 
ATOM   510   N  N     . PHE A 1 82  ? 247.459 215.246 179.821 1.00 27.02  ? 82  PHE A N     1 
ATOM   511   C  CA    . PHE A 1 82  ? 246.966 213.952 179.369 1.00 25.21  ? 82  PHE A CA    1 
ATOM   512   C  C     . PHE A 1 82  ? 246.431 213.950 177.939 1.00 24.21  ? 82  PHE A C     1 
ATOM   513   O  O     . PHE A 1 82  ? 246.202 212.876 177.399 1.00 27.13  ? 82  PHE A O     1 
ATOM   514   C  CB    . PHE A 1 82  ? 245.861 213.484 180.309 1.00 25.01  ? 82  PHE A CB    1 
ATOM   515   C  CG    . PHE A 1 82  ? 246.333 213.178 181.712 1.00 24.08  ? 82  PHE A CG    1 
ATOM   516   C  CD1   . PHE A 1 82  ? 247.370 212.281 181.931 1.00 25.60  ? 82  PHE A CD1   1 
ATOM   517   C  CD2   . PHE A 1 82  ? 245.742 213.786 182.803 1.00 24.26  ? 82  PHE A CD2   1 
ATOM   518   C  CE1   . PHE A 1 82  ? 247.793 211.992 183.219 1.00 26.23  ? 82  PHE A CE1   1 
ATOM   519   C  CE2   . PHE A 1 82  ? 246.165 213.489 184.088 1.00 24.57  ? 82  PHE A CE2   1 
ATOM   520   C  CZ    . PHE A 1 82  ? 247.193 212.602 184.293 1.00 25.28  ? 82  PHE A CZ    1 
ATOM   521   N  N     . GLY A 1 83  ? 246.205 215.115 177.333 1.00 23.79  ? 83  GLY A N     1 
ATOM   522   C  CA    . GLY A 1 83  ? 245.939 215.193 175.905 1.00 23.96  ? 83  GLY A CA    1 
ATOM   523   C  C     . GLY A 1 83  ? 244.452 215.267 175.563 1.00 24.49  ? 83  GLY A C     1 
ATOM   524   O  O     . GLY A 1 83  ? 244.096 215.670 174.461 1.00 26.25  ? 83  GLY A O     1 
ATOM   525   N  N     . ARG A 1 84  ? 243.583 214.862 176.492 1.00 23.45  ? 84  ARG A N     1 
ATOM   526   C  CA    . ARG A 1 84  ? 242.157 214.800 176.221 1.00 22.62  ? 84  ARG A CA    1 
ATOM   527   C  C     . ARG A 1 84  ? 241.417 214.621 177.541 1.00 20.30  ? 84  ARG A C     1 
ATOM   528   O  O     . ARG A 1 84  ? 242.027 214.365 178.578 1.00 20.51  ? 84  ARG A O     1 
ATOM   529   C  CB    . ARG A 1 84  ? 241.803 213.646 175.274 1.00 24.71  ? 84  ARG A CB    1 
ATOM   530   C  CG    . ARG A 1 84  ? 242.184 212.280 175.826 1.00 26.79  ? 84  ARG A CG    1 
ATOM   531   C  CD    . ARG A 1 84  ? 242.110 211.203 174.763 1.00 29.95  ? 84  ARG A CD    1 
ATOM   532   N  NE    . ARG A 1 84  ? 240.749 210.680 174.620 1.00 30.66  ? 84  ARG A NE    1 
ATOM   533   C  CZ    . ARG A 1 84  ? 240.043 210.617 173.502 1.00 32.21  ? 84  ARG A CZ    1 
ATOM   534   N  NH1   . ARG A 1 84  ? 240.510 211.137 172.384 1.00 35.84  ? 84  ARG A NH1   1 
ATOM   535   N  NH2   . ARG A 1 84  ? 238.840 210.072 173.524 1.00 30.56  ? 84  ARG A NH2   1 
ATOM   536   N  N     . VAL A 1 85  ? 240.094 214.790 177.481 1.00 18.45  ? 85  VAL A N     1 
ATOM   537   C  CA    . VAL A 1 85  ? 239.218 214.500 178.598 1.00 17.32  ? 85  VAL A CA    1 
ATOM   538   C  C     . VAL A 1 85  ? 238.124 213.556 178.106 1.00 15.65  ? 85  VAL A C     1 
ATOM   539   O  O     . VAL A 1 85  ? 237.419 213.871 177.163 1.00 15.53  ? 85  VAL A O     1 
ATOM   540   C  CB    . VAL A 1 85  ? 238.629 215.778 179.212 1.00 18.67  ? 85  VAL A CB    1 
ATOM   541   C  CG1   . VAL A 1 85  ? 237.607 215.454 180.292 1.00 18.80  ? 85  VAL A CG1   1 
ATOM   542   C  CG2   . VAL A 1 85  ? 239.726 216.671 179.774 1.00 19.31  ? 85  VAL A CG2   1 
ATOM   543   N  N     . ASP A 1 86  ? 237.966 212.425 178.799 1.00 15.34  ? 86  ASP A N     1 
ATOM   544   C  CA    . ASP A 1 86  ? 236.985 211.417 178.437 1.00 15.63  ? 86  ASP A CA    1 
ATOM   545   C  C     . ASP A 1 86  ? 235.824 211.371 179.428 1.00 13.88  ? 86  ASP A C     1 
ATOM   546   O  O     . ASP A 1 86  ? 234.709 211.031 179.034 1.00 13.27  ? 86  ASP A O     1 
ATOM   547   C  CB    . ASP A 1 86  ? 237.630 210.047 178.364 1.00 17.69  ? 86  ASP A CB    1 
ATOM   548   C  CG    . ASP A 1 86  ? 238.753 209.979 177.342 1.00 20.26  ? 86  ASP A CG    1 
ATOM   549   O  OD1   . ASP A 1 86  ? 238.449 210.153 176.151 1.00 22.52  ? 86  ASP A OD1   1 
ATOM   550   O  OD2   . ASP A 1 86  ? 239.917 209.787 177.749 1.00 21.29  ? 86  ASP A OD2   1 
ATOM   551   N  N     . VAL A 1 87  ? 236.097 211.662 180.703 1.00 12.55  ? 87  VAL A N     1 
ATOM   552   C  CA    . VAL A 1 87  ? 235.110 211.536 181.756 1.00 12.19  ? 87  VAL A CA    1 
ATOM   553   C  C     . VAL A 1 87  ? 235.172 212.788 182.621 1.00 11.36  ? 87  VAL A C     1 
ATOM   554   O  O     . VAL A 1 87  ? 236.253 213.270 182.953 1.00 11.75  ? 87  VAL A O     1 
ATOM   555   C  CB    . VAL A 1 87  ? 235.343 210.268 182.597 1.00 11.89  ? 87  VAL A CB    1 
ATOM   556   C  CG1   . VAL A 1 87  ? 234.344 210.159 183.738 1.00 11.82  ? 87  VAL A CG1   1 
ATOM   557   C  CG2   . VAL A 1 87  ? 235.294 209.004 181.742 1.00 11.79  ? 87  VAL A CG2   1 
ATOM   558   N  N     . ALA A 1 88  ? 233.998 213.300 183.001 1.00 10.74  ? 88  ALA A N     1 
ATOM   559   C  CA    . ALA A 1 88  ? 233.901 214.339 184.011 1.00 10.54  ? 88  ALA A CA    1 
ATOM   560   C  C     . ALA A 1 88  ? 233.002 213.826 185.130 1.00 10.88  ? 88  ALA A C     1 
ATOM   561   O  O     . ALA A 1 88  ? 231.877 213.396 184.866 1.00 10.88  ? 88  ALA A O     1 
ATOM   562   C  CB    . ALA A 1 88  ? 233.370 215.634 183.416 1.00 10.90  ? 88  ALA A CB    1 
ATOM   563   N  N     . VAL A 1 89  ? 233.512 213.875 186.361 1.00 10.46  ? 89  VAL A N     1 
ATOM   564   C  CA    . VAL A 1 89  ? 232.739 213.516 187.534 1.00 10.36  ? 89  VAL A CA    1 
ATOM   565   C  C     . VAL A 1 89  ? 232.621 214.734 188.444 1.00 11.03  ? 89  VAL A C     1 
ATOM   566   O  O     . VAL A 1 89  ? 233.620 215.222 188.971 1.00 11.71  ? 89  VAL A O     1 
ATOM   567   C  CB    . VAL A 1 89  ? 233.372 212.330 188.267 1.00 10.40  ? 89  VAL A CB    1 
ATOM   568   C  CG1   . VAL A 1 89  ? 232.468 211.851 189.389 1.00 10.58  ? 89  VAL A CG1   1 
ATOM   569   C  CG2   . VAL A 1 89  ? 233.688 211.185 187.322 1.00 10.35  ? 89  VAL A CG2   1 
ATOM   570   N  N     . ASN A 1 90  ? 231.390 215.208 188.631 1.00 11.74  ? 90  ASN A N     1 
ATOM   571   C  CA    . ASN A 1 90  ? 231.120 216.360 189.470 1.00 12.77  ? 90  ASN A CA    1 
ATOM   572   C  C     . ASN A 1 90  ? 230.811 215.895 190.887 1.00 14.04  ? 90  ASN A C     1 
ATOM   573   O  O     . ASN A 1 90  ? 229.709 215.415 191.142 1.00 14.99  ? 90  ASN A O     1 
ATOM   574   C  CB    . ASN A 1 90  ? 229.966 217.191 188.919 1.00 12.96  ? 90  ASN A CB    1 
ATOM   575   C  CG    . ASN A 1 90  ? 230.350 217.943 187.668 1.00 14.16  ? 90  ASN A CG    1 
ATOM   576   O  OD1   . ASN A 1 90  ? 231.162 218.879 187.729 1.00 15.61  ? 90  ASN A OD1   1 
ATOM   577   N  ND2   . ASN A 1 90  ? 229.796 217.550 186.529 1.00 14.77  ? 90  ASN A ND2   1 
ATOM   578   N  N     . CYS A 1 91  ? 231.769 216.041 191.800 1.00 15.10  ? 91  CYS A N     1 
ATOM   579   C  CA    . CYS A 1 91  ? 231.572 215.620 193.182 1.00 16.47  ? 91  CYS A CA    1 
ATOM   580   C  C     . CYS A 1 91  ? 231.730 216.766 194.182 1.00 18.03  ? 91  CYS A C     1 
ATOM   581   O  O     . CYS A 1 91  ? 231.562 216.547 195.375 1.00 21.05  ? 91  CYS A O     1 
ATOM   582   C  CB    . CYS A 1 91  ? 232.553 214.528 193.590 1.00 18.07  ? 91  CYS A CB    1 
ATOM   583   S  SG    . CYS A 1 91  ? 232.322 212.969 192.706 1.00 20.76  ? 91  CYS A SG    1 
ATOM   584   N  N     . ALA A 1 92  ? 232.075 217.974 193.729 1.00 18.49  ? 92  ALA A N     1 
ATOM   585   C  CA    . ALA A 1 92  ? 232.174 219.098 194.651 1.00 18.88  ? 92  ALA A CA    1 
ATOM   586   C  C     . ALA A 1 92  ? 230.785 219.510 195.110 1.00 19.70  ? 92  ALA A C     1 
ATOM   587   O  O     . ALA A 1 92  ? 229.847 219.585 194.320 1.00 21.97  ? 92  ALA A O     1 
ATOM   588   C  CB    . ALA A 1 92  ? 232.893 220.261 194.019 1.00 18.41  ? 92  ALA A CB    1 
ATOM   589   N  N     . GLY A 1 93  ? 230.652 219.763 196.403 1.00 19.50  ? 93  GLY A N     1 
ATOM   590   C  CA    . GLY A 1 93  ? 229.363 220.150 196.938 1.00 19.24  ? 93  GLY A CA    1 
ATOM   591   C  C     . GLY A 1 93  ? 229.502 220.642 198.370 1.00 18.81  ? 93  GLY A C     1 
ATOM   592   O  O     . GLY A 1 93  ? 230.395 220.206 199.088 1.00 20.50  ? 93  GLY A O     1 
ATOM   593   N  N     . ILE A 1 94  ? 228.612 221.557 198.758 1.00 17.57  ? 94  ILE A N     1 
ATOM   594   C  CA    . ILE A 1 94  ? 228.519 222.025 200.126 1.00 16.81  ? 94  ILE A CA    1 
ATOM   595   C  C     . ILE A 1 94  ? 227.064 221.931 200.557 1.00 17.40  ? 94  ILE A C     1 
ATOM   596   O  O     . ILE A 1 94  ? 226.160 221.845 199.731 1.00 18.00  ? 94  ILE A O     1 
ATOM   597   C  CB    . ILE A 1 94  ? 229.043 223.467 200.251 1.00 16.97  ? 94  ILE A CB    1 
ATOM   598   C  CG1   . ILE A 1 94  ? 228.256 224.426 199.359 1.00 16.99  ? 94  ILE A CG1   1 
ATOM   599   C  CG2   . ILE A 1 94  ? 230.536 223.532 199.938 1.00 16.89  ? 94  ILE A CG2   1 
ATOM   600   C  CD1   . ILE A 1 94  ? 228.553 225.889 199.618 1.00 17.37  ? 94  ILE A CD1   1 
ATOM   601   N  N     . ALA A 1 95  ? 226.839 221.997 201.868 1.00 18.32  ? 95  ALA A N     1 
ATOM   602   C  CA    . ALA A 1 95  ? 225.496 222.064 202.415 1.00 19.89  ? 95  ALA A CA    1 
ATOM   603   C  C     . ALA A 1 95  ? 225.459 223.057 203.572 1.00 20.36  ? 95  ALA A C     1 
ATOM   604   O  O     . ALA A 1 95  ? 226.479 223.403 204.151 1.00 19.38  ? 95  ALA A O     1 
ATOM   605   C  CB    . ALA A 1 95  ? 225.049 220.689 202.850 1.00 20.40  ? 95  ALA A CB    1 
ATOM   606   N  N     . VAL A 1 96  ? 224.247 223.471 203.919 1.00 20.71  ? 96  VAL A N     1 
ATOM   607   C  CA    . VAL A 1 96  ? 223.965 224.163 205.159 1.00 21.08  ? 96  VAL A CA    1 
ATOM   608   C  C     . VAL A 1 96  ? 222.801 223.441 205.826 1.00 20.76  ? 96  VAL A C     1 
ATOM   609   O  O     . VAL A 1 96  ? 221.944 222.867 205.160 1.00 23.03  ? 96  VAL A O     1 
ATOM   610   C  CB    . VAL A 1 96  ? 223.630 225.647 204.926 1.00 22.46  ? 96  VAL A CB    1 
ATOM   611   C  CG1   . VAL A 1 96  ? 224.850 226.417 204.460 1.00 23.48  ? 96  VAL A CG1   1 
ATOM   612   C  CG2   . VAL A 1 96  ? 222.491 225.820 203.931 1.00 23.11  ? 96  VAL A CG2   1 
ATOM   613   N  N     . ALA A 1 97  ? 222.767 223.506 207.155 1.00 20.11  ? 97  ALA A N     1 
ATOM   614   C  CA    . ALA A 1 97  ? 221.630 223.054 207.929 1.00 19.47  ? 97  ALA A CA    1 
ATOM   615   C  C     . ALA A 1 97  ? 220.919 224.291 208.482 1.00 18.42  ? 97  ALA A C     1 
ATOM   616   O  O     . ALA A 1 97  ? 221.361 224.880 209.466 1.00 19.55  ? 97  ALA A O     1 
ATOM   617   C  CB    . ALA A 1 97  ? 222.097 222.111 209.016 1.00 19.56  ? 97  ALA A CB    1 
ATOM   618   N  N     . SER A 1 98  ? 219.851 224.692 207.796 1.00 16.56  ? 98  SER A N     1 
ATOM   619   C  CA    . SER A 1 98  ? 219.124 225.894 208.162 1.00 15.93  ? 98  SER A CA    1 
ATOM   620   C  C     . SER A 1 98  ? 217.666 225.755 207.749 1.00 15.10  ? 98  SER A C     1 
ATOM   621   O  O     . SER A 1 98  ? 217.375 225.467 206.590 1.00 15.14  ? 98  SER A O     1 
ATOM   622   C  CB    . SER A 1 98  ? 219.760 227.097 207.505 1.00 16.51  ? 98  SER A CB    1 
ATOM   623   O  OG    . SER A 1 98  ? 219.176 228.296 207.985 1.00 16.95  ? 98  SER A OG    1 
ATOM   624   N  N     . LYS A 1 99  ? 216.753 225.954 208.691 1.00 14.38  ? 99  LYS A N     1 
ATOM   625   C  CA    . LYS A 1 99  ? 215.336 225.926 208.382 1.00 15.04  ? 99  LYS A CA    1 
ATOM   626   C  C     . LYS A 1 99  ? 214.957 227.138 207.535 1.00 14.39  ? 99  LYS A C     1 
ATOM   627   O  O     . LYS A 1 99  ? 215.576 228.191 207.628 1.00 14.03  ? 99  LYS A O     1 
ATOM   628   C  CB    . LYS A 1 99  ? 214.485 225.943 209.654 1.00 16.27  ? 99  LYS A CB    1 
ATOM   629   C  CG    . LYS A 1 99  ? 214.643 224.728 210.538 1.00 18.29  ? 99  LYS A CG    1 
ATOM   630   C  CD    . LYS A 1 99  ? 213.605 224.743 211.655 1.00 19.62  ? 99  LYS A CD    1 
ATOM   631   C  CE    . LYS A 1 99  ? 213.568 223.488 212.446 1.00 21.32  ? 99  LYS A CE    1 
ATOM   632   N  NZ    . LYS A 1 99  ? 213.173 223.816 213.818 1.00 23.77  ? 99  LYS A NZ    1 
ATOM   633   N  N     . THR A 1 100 ? 213.939 226.972 206.691 1.00 13.93  ? 100 THR A N     1 
ATOM   634   C  CA    . THR A 1 100 ? 213.405 228.069 205.899 1.00 14.46  ? 100 THR A CA    1 
ATOM   635   C  C     . THR A 1 100 ? 212.964 229.205 206.830 1.00 14.21  ? 100 THR A C     1 
ATOM   636   O  O     . THR A 1 100 ? 213.281 230.367 206.598 1.00 13.63  ? 100 THR A O     1 
ATOM   637   C  CB    . THR A 1 100 ? 212.237 227.588 205.036 1.00 14.60  ? 100 THR A CB    1 
ATOM   638   O  OG1   . THR A 1 100 ? 212.722 226.566 204.164 1.00 14.76  ? 100 THR A OG1   1 
ATOM   639   C  CG2   . THR A 1 100 ? 211.648 228.729 204.224 1.00 14.73  ? 100 THR A CG2   1 
ATOM   640   N  N     . TYR A 1 101 ? 212.200 228.853 207.863 1.00 14.24  ? 101 TYR A N     1 
ATOM   641   C  CA    . TYR A 1 101 ? 211.756 229.810 208.856 1.00 14.45  ? 101 TYR A CA    1 
ATOM   642   C  C     . TYR A 1 101 ? 211.462 229.070 210.151 1.00 15.25  ? 101 TYR A C     1 
ATOM   643   O  O     . TYR A 1 101 ? 210.860 228.003 210.132 1.00 16.55  ? 101 TYR A O     1 
ATOM   644   C  CB    . TYR A 1 101 ? 210.528 230.578 208.373 1.00 15.33  ? 101 TYR A CB    1 
ATOM   645   C  CG    . TYR A 1 101 ? 210.031 231.588 209.391 1.00 16.06  ? 101 TYR A CG    1 
ATOM   646   C  CD1   . TYR A 1 101 ? 210.781 232.727 209.674 1.00 17.25  ? 101 TYR A CD1   1 
ATOM   647   C  CD2   . TYR A 1 101 ? 208.840 231.394 210.081 1.00 17.13  ? 101 TYR A CD2   1 
ATOM   648   C  CE1   . TYR A 1 101 ? 210.356 233.646 210.619 1.00 17.52  ? 101 TYR A CE1   1 
ATOM   649   C  CE2   . TYR A 1 101 ? 208.396 232.320 211.011 1.00 17.53  ? 101 TYR A CE2   1 
ATOM   650   C  CZ    . TYR A 1 101 ? 209.163 233.441 211.286 1.00 17.67  ? 101 TYR A CZ    1 
ATOM   651   O  OH    . TYR A 1 101 ? 208.737 234.344 212.214 1.00 19.54  ? 101 TYR A OH    1 
ATOM   652   N  N     . ASN A 1 102 ? 211.904 229.650 211.267 1.00 16.24  ? 102 ASN A N     1 
ATOM   653   C  CA    . ASN A 1 102 ? 211.671 229.098 212.591 1.00 18.00  ? 102 ASN A CA    1 
ATOM   654   C  C     . ASN A 1 102 ? 210.820 230.109 213.361 1.00 17.35  ? 102 ASN A C     1 
ATOM   655   O  O     . ASN A 1 102 ? 211.298 231.188 213.717 1.00 17.60  ? 102 ASN A O     1 
ATOM   656   C  CB    . ASN A 1 102 ? 212.994 228.814 213.299 1.00 18.40  ? 102 ASN A CB    1 
ATOM   657   C  CG    . ASN A 1 102 ? 212.835 227.995 214.558 1.00 20.64  ? 102 ASN A CG    1 
ATOM   658   O  OD1   . ASN A 1 102 ? 211.868 228.164 215.306 1.00 20.61  ? 102 ASN A OD1   1 
ATOM   659   N  ND2   . ASN A 1 102 ? 213.780 227.110 214.829 1.00 22.22  ? 102 ASN A ND2   1 
ATOM   660   N  N     . LEU A 1 103 ? 209.556 229.768 213.598 1.00 18.25  ? 103 LEU A N     1 
ATOM   661   C  CA    . LEU A 1 103 ? 208.628 230.691 214.237 1.00 20.75  ? 103 LEU A CA    1 
ATOM   662   C  C     . LEU A 1 103 ? 209.027 230.940 215.693 1.00 22.22  ? 103 LEU A C     1 
ATOM   663   O  O     . LEU A 1 103 ? 208.990 232.074 216.163 1.00 22.29  ? 103 LEU A O     1 
ATOM   664   C  CB    . LEU A 1 103 ? 207.194 230.176 214.148 1.00 21.61  ? 103 LEU A CB    1 
ATOM   665   C  CG    . LEU A 1 103 ? 206.134 231.027 214.859 1.00 22.36  ? 103 LEU A CG    1 
ATOM   666   C  CD1   . LEU A 1 103 ? 206.092 232.442 214.341 1.00 22.16  ? 103 LEU A CD1   1 
ATOM   667   C  CD2   . LEU A 1 103 ? 204.760 230.395 214.748 1.00 22.63  ? 103 LEU A CD2   1 
ATOM   668   N  N     . LYS A 1 104 ? 209.392 229.877 216.410 1.00 24.43  ? 104 LYS A N     1 
ATOM   669   C  CA    . LYS A 1 104 ? 209.700 229.988 217.831 1.00 27.20  ? 104 LYS A CA    1 
ATOM   670   C  C     . LYS A 1 104 ? 210.910 230.900 218.043 1.00 27.01  ? 104 LYS A C     1 
ATOM   671   O  O     . LYS A 1 104 ? 210.902 231.757 218.921 1.00 28.21  ? 104 LYS A O     1 
ATOM   672   C  CB    . LYS A 1 104 ? 209.943 228.610 218.446 1.00 30.08  ? 104 LYS A CB    1 
ATOM   673   C  CG    . LYS A 1 104 ? 208.807 227.638 218.186 1.00 35.07  ? 104 LYS A CG    1 
ATOM   674   C  CD    . LYS A 1 104 ? 208.930 226.305 218.901 1.00 36.48  ? 104 LYS A CD    1 
ATOM   675   C  CE    . LYS A 1 104 ? 207.958 226.216 220.027 1.00 38.88  ? 104 LYS A CE    1 
ATOM   676   N  NZ    . LYS A 1 104 ? 206.557 226.223 219.589 1.00 38.73  ? 104 LYS A NZ    1 
ATOM   677   N  N     . LYS A 1 105 ? 211.953 230.707 217.231 1.00 26.98  ? 105 LYS A N     1 
ATOM   678   C  CA    . LYS A 1 105 ? 213.164 231.502 217.333 1.00 28.60  ? 105 LYS A CA    1 
ATOM   679   C  C     . LYS A 1 105 ? 213.074 232.802 216.533 1.00 27.15  ? 105 LYS A C     1 
ATOM   680   O  O     . LYS A 1 105 ? 213.944 233.657 216.669 1.00 29.12  ? 105 LYS A O     1 
ATOM   681   C  CB    . LYS A 1 105 ? 214.366 230.695 216.844 1.00 33.25  ? 105 LYS A CB    1 
ATOM   682   C  CG    . LYS A 1 105 ? 214.755 229.552 217.752 1.00 38.59  ? 105 LYS A CG    1 
ATOM   683   C  CD    . LYS A 1 105 ? 215.882 228.703 217.188 1.00 45.05  ? 105 LYS A CD    1 
ATOM   684   C  CE    . LYS A 1 105 ? 217.216 229.384 217.171 1.00 50.19  ? 105 LYS A CE    1 
ATOM   685   N  NZ    . LYS A 1 105 ? 217.703 229.673 218.524 1.00 53.05  ? 105 LYS A NZ    1 
ATOM   686   N  N     . GLY A 1 106 ? 212.051 232.957 215.691 1.00 25.42  ? 106 GLY A N     1 
ATOM   687   C  CA    . GLY A 1 106 ? 211.941 234.126 214.831 1.00 24.11  ? 106 GLY A CA    1 
ATOM   688   C  C     . GLY A 1 106 ? 213.114 234.238 213.859 1.00 23.82  ? 106 GLY A C     1 
ATOM   689   O  O     . GLY A 1 106 ? 213.572 235.336 213.566 1.00 24.63  ? 106 GLY A O     1 
ATOM   690   N  N     . GLN A 1 107 ? 213.609 233.092 213.384 1.00 21.33  ? 107 GLN A N     1 
ATOM   691   C  CA    . GLN A 1 107 ? 214.809 233.035 212.569 1.00 20.01  ? 107 GLN A CA    1 
ATOM   692   C  C     . GLN A 1 107 ? 214.416 232.652 211.146 1.00 17.41  ? 107 GLN A C     1 
ATOM   693   O  O     . GLN A 1 107 ? 213.646 231.714 210.928 1.00 17.36  ? 107 GLN A O     1 
ATOM   694   C  CB    . GLN A 1 107 ? 215.791 232.012 213.131 1.00 22.89  ? 107 GLN A CB    1 
ATOM   695   C  CG    . GLN A 1 107 ? 217.070 231.882 212.316 1.00 28.06  ? 107 GLN A CG    1 
ATOM   696   C  CD    . GLN A 1 107 ? 218.086 230.956 212.953 1.00 33.64  ? 107 GLN A CD    1 
ATOM   697   O  OE1   . GLN A 1 107 ? 217.788 230.206 213.887 1.00 35.87  ? 107 GLN A OE1   1 
ATOM   698   N  NE2   . GLN A 1 107 ? 219.304 230.993 212.435 1.00 37.31  ? 107 GLN A NE2   1 
ATOM   699   N  N     . THR A 1 108 ? 214.963 233.400 210.188 1.00 14.46  ? 108 THR A N     1 
ATOM   700   C  CA    . THR A 1 108 ? 214.689 233.195 208.780 1.00 13.94  ? 108 THR A CA    1 
ATOM   701   C  C     . THR A 1 108 ? 215.967 232.713 208.108 1.00 13.30  ? 108 THR A C     1 
ATOM   702   O  O     . THR A 1 108 ? 217.059 233.191 208.398 1.00 14.10  ? 108 THR A O     1 
ATOM   703   C  CB    . THR A 1 108 ? 214.185 234.476 208.122 1.00 13.74  ? 108 THR A CB    1 
ATOM   704   O  OG1   . THR A 1 108 ? 213.038 234.945 208.825 1.00 13.96  ? 108 THR A OG1   1 
ATOM   705   C  CG2   . THR A 1 108 ? 213.795 234.236 206.678 1.00 13.92  ? 108 THR A CG2   1 
ATOM   706   N  N     . HIS A 1 109 ? 215.813 231.755 207.196 1.00 12.78  ? 109 HIS A N     1 
ATOM   707   C  CA    . HIS A 1 109 ? 216.922 231.301 206.378 1.00 12.35  ? 109 HIS A CA    1 
ATOM   708   C  C     . HIS A 1 109 ? 217.517 232.501 205.656 1.00 12.60  ? 109 HIS A C     1 
ATOM   709   O  O     . HIS A 1 109 ? 216.816 233.286 205.027 1.00 12.65  ? 109 HIS A O     1 
ATOM   710   C  CB    . HIS A 1 109 ? 216.440 230.258 205.365 1.00 12.18  ? 109 HIS A CB    1 
ATOM   711   C  CG    . HIS A 1 109 ? 217.517 229.482 204.705 1.00 12.20  ? 109 HIS A CG    1 
ATOM   712   N  ND1   . HIS A 1 109 ? 218.488 230.077 203.933 1.00 11.67  ? 109 HIS A ND1   1 
ATOM   713   C  CD2   . HIS A 1 109 ? 217.781 228.159 204.680 1.00 12.41  ? 109 HIS A CD2   1 
ATOM   714   C  CE1   . HIS A 1 109 ? 219.306 229.139 203.472 1.00 11.67  ? 109 HIS A CE1   1 
ATOM   715   N  NE2   . HIS A 1 109 ? 218.901 227.973 203.920 1.00 11.58  ? 109 HIS A NE2   1 
ATOM   716   N  N     . THR A 1 110 ? 218.836 232.620 205.710 1.00 12.90  ? 110 THR A N     1 
ATOM   717   C  CA    . THR A 1 110 ? 219.527 233.700 205.034 1.00 14.71  ? 110 THR A CA    1 
ATOM   718   C  C     . THR A 1 110 ? 219.492 233.471 203.524 1.00 14.82  ? 110 THR A C     1 
ATOM   719   O  O     . THR A 1 110 ? 219.681 232.346 203.057 1.00 15.47  ? 110 THR A O     1 
ATOM   720   C  CB    . THR A 1 110 ? 220.963 233.736 205.566 1.00 16.45  ? 110 THR A CB    1 
ATOM   721   O  OG1   . THR A 1 110 ? 220.901 234.316 206.872 1.00 16.18  ? 110 THR A OG1   1 
ATOM   722   C  CG2   . THR A 1 110 ? 221.810 234.712 204.813 1.00 19.47  ? 110 THR A CG2   1 
ATOM   723   N  N     . LEU A 1 111 ? 219.305 234.549 202.771 1.00 14.39  ? 111 LEU A N     1 
ATOM   724   C  CA    . LEU A 1 111 ? 219.346 234.480 201.319 1.00 15.39  ? 111 LEU A CA    1 
ATOM   725   C  C     . LEU A 1 111 ? 220.757 234.122 200.843 1.00 16.71  ? 111 LEU A C     1 
ATOM   726   O  O     . LEU A 1 111 ? 220.915 233.385 199.869 1.00 16.51  ? 111 LEU A O     1 
ATOM   727   C  CB    . LEU A 1 111 ? 218.858 235.785 200.702 1.00 16.07  ? 111 LEU A CB    1 
ATOM   728   C  CG    . LEU A 1 111 ? 218.712 235.799 199.176 1.00 16.67  ? 111 LEU A CG    1 
ATOM   729   C  CD1   . LEU A 1 111 ? 217.752 234.717 198.723 1.00 16.75  ? 111 LEU A CD1   1 
ATOM   730   C  CD2   . LEU A 1 111 ? 218.257 237.163 198.690 1.00 17.59  ? 111 LEU A CD2   1 
ATOM   731   N  N     . GLU A 1 112 ? 221.779 234.645 201.524 1.00 17.64  ? 112 GLU A N     1 
ATOM   732   C  CA    . GLU A 1 112 ? 223.158 234.389 201.143 1.00 19.33  ? 112 GLU A CA    1 
ATOM   733   C  C     . GLU A 1 112 ? 223.506 232.904 201.310 1.00 18.15  ? 112 GLU A C     1 
ATOM   734   O  O     . GLU A 1 112 ? 224.230 232.345 200.489 1.00 17.90  ? 112 GLU A O     1 
ATOM   735   C  CB    . GLU A 1 112 ? 224.131 235.251 201.953 1.00 22.50  ? 112 GLU A CB    1 
ATOM   736   C  CG    . GLU A 1 112 ? 224.031 236.755 201.690 1.00 27.60  ? 112 GLU A CG    1 
ATOM   737   C  CD    . GLU A 1 112 ? 222.655 237.398 201.844 1.00 32.31  ? 112 GLU A CD    1 
ATOM   738   O  OE1   . GLU A 1 112 ? 222.022 237.182 202.910 1.00 29.66  ? 112 GLU A OE1   1 
ATOM   739   O  OE2   . GLU A 1 112 ? 222.190 238.033 200.863 1.00 34.78  ? 112 GLU A OE2   1 
ATOM   740   N  N     . ASP A 1 113 ? 222.995 232.266 202.368 1.00 17.74  ? 113 ASP A N     1 
ATOM   741   C  CA    . ASP A 1 113 ? 223.220 230.850 202.574 1.00 18.59  ? 113 ASP A CA    1 
ATOM   742   C  C     . ASP A 1 113 ? 222.630 230.033 201.426 1.00 16.89  ? 113 ASP A C     1 
ATOM   743   O  O     . ASP A 1 113 ? 223.269 229.100 200.931 1.00 17.73  ? 113 ASP A O     1 
ATOM   744   C  CB    . ASP A 1 113 ? 222.659 230.388 203.902 1.00 20.65  ? 113 ASP A CB    1 
ATOM   745   C  CG    . ASP A 1 113 ? 223.659 230.428 205.044 1.00 23.54  ? 113 ASP A CG    1 
ATOM   746   O  OD1   . ASP A 1 113 ? 224.886 230.530 204.751 1.00 25.66  ? 113 ASP A OD1   1 
ATOM   747   O  OD2   . ASP A 1 113 ? 223.202 230.312 206.208 1.00 23.73  ? 113 ASP A OD2   1 
ATOM   748   N  N     . PHE A 1 114 ? 221.418 230.385 201.005 1.00 15.37  ? 114 PHE A N     1 
ATOM   749   C  CA    . PHE A 1 114 ? 220.779 229.698 199.897 1.00 14.71  ? 114 PHE A CA    1 
ATOM   750   C  C     . PHE A 1 114 ? 221.580 229.911 198.614 1.00 15.36  ? 114 PHE A C     1 
ATOM   751   O  O     . PHE A 1 114 ? 221.776 228.971 197.847 1.00 15.16  ? 114 PHE A O     1 
ATOM   752   C  CB    . PHE A 1 114 ? 219.343 230.191 199.736 1.00 13.73  ? 114 PHE A CB    1 
ATOM   753   C  CG    . PHE A 1 114 ? 218.524 229.360 198.767 1.00 12.78  ? 114 PHE A CG    1 
ATOM   754   C  CD1   . PHE A 1 114 ? 217.858 228.231 199.217 1.00 12.49  ? 114 PHE A CD1   1 
ATOM   755   C  CD2   . PHE A 1 114 ? 218.383 229.743 197.443 1.00 12.71  ? 114 PHE A CD2   1 
ATOM   756   C  CE1   . PHE A 1 114 ? 217.073 227.485 198.358 1.00 12.23  ? 114 PHE A CE1   1 
ATOM   757   C  CE2   . PHE A 1 114 ? 217.598 228.992 196.581 1.00 13.20  ? 114 PHE A CE2   1 
ATOM   758   C  CZ    . PHE A 1 114 ? 216.945 227.867 197.041 1.00 12.51  ? 114 PHE A CZ    1 
ATOM   759   N  N     . GLN A 1 115 ? 222.034 231.144 198.379 1.00 16.48  ? 115 GLN A N     1 
ATOM   760   C  CA    . GLN A 1 115 ? 222.753 231.472 197.157 1.00 17.94  ? 115 GLN A CA    1 
ATOM   761   C  C     . GLN A 1 115 ? 224.089 230.724 197.089 1.00 16.93  ? 115 GLN A C     1 
ATOM   762   O  O     . GLN A 1 115 ? 224.458 230.223 196.033 1.00 16.57  ? 115 GLN A O     1 
ATOM   763   C  CB    . GLN A 1 115 ? 222.971 232.979 197.053 1.00 20.74  ? 115 GLN A CB    1 
ATOM   764   C  CG    . GLN A 1 115 ? 223.658 233.425 195.766 1.00 25.42  ? 115 GLN A CG    1 
ATOM   765   C  CD    . GLN A 1 115 ? 222.826 233.172 194.525 1.00 30.95  ? 115 GLN A CD    1 
ATOM   766   O  OE1   . GLN A 1 115 ? 221.821 233.852 194.296 1.00 34.21  ? 115 GLN A OE1   1 
ATOM   767   N  NE2   . GLN A 1 115 ? 223.185 232.153 193.753 1.00 32.85  ? 115 GLN A NE2   1 
ATOM   768   N  N     . ARG A 1 116 ? 224.807 230.653 198.209 1.00 16.77  ? 116 ARG A N     1 
ATOM   769   C  CA    . ARG A 1 116 ? 226.122 230.030 198.229 1.00 17.82  ? 116 ARG A CA    1 
ATOM   770   C  C     . ARG A 1 116 ? 226.018 228.541 197.894 1.00 15.09  ? 116 ARG A C     1 
ATOM   771   O  O     . ARG A 1 116 ? 226.856 228.002 197.191 1.00 14.88  ? 116 ARG A O     1 
ATOM   772   C  CB    . ARG A 1 116 ? 226.791 230.236 199.593 1.00 21.71  ? 116 ARG A CB    1 
ATOM   773   C  CG    . ARG A 1 116 ? 228.313 230.223 199.550 1.00 28.02  ? 116 ARG A CG    1 
ATOM   774   C  CD    . ARG A 1 116 ? 228.932 230.367 200.921 1.00 33.23  ? 116 ARG A CD    1 
ATOM   775   N  NE    . ARG A 1 116 ? 228.856 229.092 201.637 1.00 37.25  ? 116 ARG A NE    1 
ATOM   776   C  CZ    . ARG A 1 116 ? 228.050 228.806 202.650 1.00 41.55  ? 116 ARG A CZ    1 
ATOM   777   N  NH1   . ARG A 1 116 ? 227.191 229.703 203.109 1.00 40.77  ? 116 ARG A NH1   1 
ATOM   778   N  NH2   . ARG A 1 116 ? 228.111 227.593 203.177 1.00 43.19  ? 116 ARG A NH2   1 
ATOM   779   N  N     . VAL A 1 117 ? 224.997 227.866 198.424 1.00 13.90  ? 117 VAL A N     1 
ATOM   780   C  CA    . VAL A 1 117 ? 224.815 226.451 198.152 1.00 13.07  ? 117 VAL A CA    1 
ATOM   781   C  C     . VAL A 1 117 ? 224.478 226.230 196.678 1.00 12.47  ? 117 VAL A C     1 
ATOM   782   O  O     . VAL A 1 117 ? 225.024 225.320 196.052 1.00 12.32  ? 117 VAL A O     1 
ATOM   783   C  CB    . VAL A 1 117 ? 223.752 225.854 199.076 1.00 12.94  ? 117 VAL A CB    1 
ATOM   784   C  CG1   . VAL A 1 117 ? 223.418 224.422 198.686 1.00 13.43  ? 117 VAL A CG1   1 
ATOM   785   C  CG2   . VAL A 1 117 ? 224.171 225.936 200.534 1.00 13.22  ? 117 VAL A CG2   1 
ATOM   786   N  N     . LEU A 1 118 ? 223.599 227.058 196.111 1.00 12.82  ? 118 LEU A N     1 
ATOM   787   C  CA    . LEU A 1 118 ? 223.259 226.941 194.699 1.00 14.02  ? 118 LEU A CA    1 
ATOM   788   C  C     . LEU A 1 118 ? 224.483 227.160 193.818 1.00 13.78  ? 118 LEU A C     1 
ATOM   789   O  O     . LEU A 1 118 ? 224.683 226.438 192.840 1.00 13.49  ? 118 LEU A O     1 
ATOM   790   C  CB    . LEU A 1 118 ? 222.172 227.934 194.291 1.00 15.67  ? 118 LEU A CB    1 
ATOM   791   C  CG    . LEU A 1 118 ? 220.743 227.637 194.734 1.00 19.11  ? 118 LEU A CG    1 
ATOM   792   C  CD1   . LEU A 1 118 ? 219.830 228.640 194.027 1.00 20.33  ? 118 LEU A CD1   1 
ATOM   793   C  CD2   . LEU A 1 118 ? 220.286 226.237 194.430 1.00 20.08  ? 118 LEU A CD2   1 
ATOM   794   N  N     . ASP A 1 119 ? 225.287 228.177 194.140 1.00 14.79  ? 119 ASP A N     1 
ATOM   795   C  CA    . ASP A 1 119 ? 226.423 228.532 193.306 1.00 16.68  ? 119 ASP A CA    1 
ATOM   796   C  C     . ASP A 1 119 ? 227.409 227.375 193.186 1.00 14.97  ? 119 ASP A C     1 
ATOM   797   O  O     . ASP A 1 119 ? 227.877 227.067 192.096 1.00 15.63  ? 119 ASP A O     1 
ATOM   798   C  CB    . ASP A 1 119 ? 227.100 229.786 193.818 1.00 20.17  ? 119 ASP A CB    1 
ATOM   799   C  CG    . ASP A 1 119 ? 226.239 231.034 193.660 1.00 25.59  ? 119 ASP A CG    1 
ATOM   800   O  OD1   . ASP A 1 119 ? 225.077 230.906 193.205 1.00 28.46  ? 119 ASP A OD1   1 
ATOM   801   O  OD2   . ASP A 1 119 ? 226.707 232.131 194.037 1.00 31.38  ? 119 ASP A OD2   1 
ATOM   802   N  N     . VAL A 1 120 ? 227.725 226.729 194.311 1.00 14.09  ? 120 VAL A N     1 
ATOM   803   C  CA    . VAL A 1 120 ? 228.694 225.649 194.288 1.00 13.76  ? 120 VAL A CA    1 
ATOM   804   C  C     . VAL A 1 120 ? 228.061 224.373 193.731 1.00 13.07  ? 120 VAL A C     1 
ATOM   805   O  O     . VAL A 1 120 ? 228.587 223.769 192.802 1.00 12.94  ? 120 VAL A O     1 
ATOM   806   C  CB    . VAL A 1 120 ? 229.287 225.423 195.688 1.00 15.15  ? 120 VAL A CB    1 
ATOM   807   C  CG1   . VAL A 1 120 ? 230.139 224.169 195.737 1.00 15.48  ? 120 VAL A CG1   1 
ATOM   808   C  CG2   . VAL A 1 120 ? 230.100 226.641 196.124 1.00 15.91  ? 120 VAL A CG2   1 
ATOM   809   N  N     . ASN A 1 121 ? 226.938 223.949 194.309 1.00 11.81  ? 121 ASN A N     1 
ATOM   810   C  CA    . ASN A 1 121 ? 226.358 222.660 193.972 1.00 11.38  ? 121 ASN A CA    1 
ATOM   811   C  C     . ASN A 1 121 ? 225.797 222.658 192.554 1.00 11.56  ? 121 ASN A C     1 
ATOM   812   O  O     . ASN A 1 121 ? 226.083 221.755 191.772 1.00 12.70  ? 121 ASN A O     1 
ATOM   813   C  CB    . ASN A 1 121 ? 225.299 222.265 194.980 1.00 10.70  ? 121 ASN A CB    1 
ATOM   814   C  CG    . ASN A 1 121 ? 225.862 222.046 196.363 1.00 11.01  ? 121 ASN A CG    1 
ATOM   815   O  OD1   . ASN A 1 121 ? 227.044 222.288 196.607 1.00 11.87  ? 121 ASN A OD1   1 
ATOM   816   N  ND2   . ASN A 1 121 ? 225.027 221.616 197.294 1.00 11.23  ? 121 ASN A ND2   1 
ATOM   817   N  N     . LEU A 1 122 ? 224.992 223.668 192.223 1.00 11.43  ? 122 LEU A N     1 
ATOM   818   C  CA    . LEU A 1 122 ? 224.208 223.649 190.998 1.00 11.47  ? 122 LEU A CA    1 
ATOM   819   C  C     . LEU A 1 122 ? 224.910 224.436 189.900 1.00 11.85  ? 122 LEU A C     1 
ATOM   820   O  O     . LEU A 1 122 ? 225.171 223.898 188.826 1.00 11.79  ? 122 LEU A O     1 
ATOM   821   C  CB    . LEU A 1 122 ? 222.801 224.203 191.253 1.00 11.18  ? 122 LEU A CB    1 
ATOM   822   C  CG    . LEU A 1 122 ? 221.852 224.224 190.052 1.00 11.01  ? 122 LEU A CG    1 
ATOM   823   C  CD1   . LEU A 1 122 ? 221.845 222.899 189.302 1.00 11.06  ? 122 LEU A CD1   1 
ATOM   824   C  CD2   . LEU A 1 122 ? 220.455 224.584 190.511 1.00 11.19  ? 122 LEU A CD2   1 
ATOM   825   N  N     . MET A 1 123 ? 225.204 225.710 190.160 1.00 12.47  ? 123 MET A N     1 
ATOM   826   C  CA    . MET A 1 123 ? 225.891 226.529 189.166 1.00 14.72  ? 123 MET A CA    1 
ATOM   827   C  C     . MET A 1 123 ? 227.289 225.976 188.886 1.00 13.08  ? 123 MET A C     1 
ATOM   828   O  O     . MET A 1 123 ? 227.737 225.962 187.745 1.00 13.39  ? 123 MET A O     1 
ATOM   829   C  CB    . MET A 1 123 ? 225.955 227.987 189.630 1.00 17.83  ? 123 MET A CB    1 
ATOM   830   C  CG    . MET A 1 123 ? 226.513 228.946 188.604 1.00 22.10  ? 123 MET A CG    1 
ATOM   831   S  SD    . MET A 1 123 ? 228.288 229.219 188.820 1.00 30.72  ? 123 MET A SD    1 
ATOM   832   C  CE    . MET A 1 123 ? 228.275 230.225 190.317 1.00 30.11  ? 123 MET A CE    1 
ATOM   833   N  N     . GLY A 1 124 ? 227.977 225.503 189.929 1.00 12.30  ? 124 GLY A N     1 
ATOM   834   C  CA    . GLY A 1 124 ? 229.304 224.945 189.751 1.00 11.70  ? 124 GLY A CA    1 
ATOM   835   C  C     . GLY A 1 124 ? 229.283 223.694 188.876 1.00 11.39  ? 124 GLY A C     1 
ATOM   836   O  O     . GLY A 1 124 ? 230.144 223.497 188.024 1.00 10.99  ? 124 GLY A O     1 
ATOM   837   N  N     . THR A 1 125 ? 228.286 222.833 189.093 1.00 10.62  ? 125 THR A N     1 
ATOM   838   C  CA    . THR A 1 125 ? 228.148 221.629 188.288 1.00 10.75  ? 125 THR A CA    1 
ATOM   839   C  C     . THR A 1 125 ? 227.921 221.995 186.822 1.00 10.29  ? 125 THR A C     1 
ATOM   840   O  O     . THR A 1 125 ? 228.541 221.421 185.932 1.00 10.46  ? 125 THR A O     1 
ATOM   841   C  CB    . THR A 1 125 ? 227.025 220.746 188.816 1.00 10.62  ? 125 THR A CB    1 
ATOM   842   O  OG1   . THR A 1 125 ? 227.486 220.136 190.019 1.00 10.92  ? 125 THR A OG1   1 
ATOM   843   C  CG2   . THR A 1 125 ? 226.663 219.662 187.820 1.00 11.24  ? 125 THR A CG2   1 
ATOM   844   N  N     . PHE A 1 126 ? 227.005 222.928 186.563 1.00 10.54  ? 126 PHE A N     1 
ATOM   845   C  CA    . PHE A 1 126 ? 226.715 223.319 185.194 1.00 10.98  ? 126 PHE A CA    1 
ATOM   846   C  C     . PHE A 1 126 ? 227.933 223.981 184.553 1.00 10.89  ? 126 PHE A C     1 
ATOM   847   O  O     . PHE A 1 126 ? 228.188 223.795 183.366 1.00 10.96  ? 126 PHE A O     1 
ATOM   848   C  CB    . PHE A 1 126 ? 225.508 224.264 185.153 1.00 12.14  ? 126 PHE A CB    1 
ATOM   849   C  CG    . PHE A 1 126 ? 225.131 224.663 183.744 1.00 13.58  ? 126 PHE A CG    1 
ATOM   850   C  CD1   . PHE A 1 126 ? 224.480 223.769 182.902 1.00 14.74  ? 126 PHE A CD1   1 
ATOM   851   C  CD2   . PHE A 1 126 ? 225.477 225.916 183.254 1.00 14.19  ? 126 PHE A CD2   1 
ATOM   852   C  CE1   . PHE A 1 126 ? 224.170 224.135 181.603 1.00 15.91  ? 126 PHE A CE1   1 
ATOM   853   C  CE2   . PHE A 1 126 ? 225.145 226.275 181.959 1.00 14.93  ? 126 PHE A CE2   1 
ATOM   854   C  CZ    . PHE A 1 126 ? 224.486 225.398 181.140 1.00 15.30  ? 126 PHE A CZ    1 
ATOM   855   N  N     . ASN A 1 127 ? 228.669 224.778 185.332 1.00 11.22  ? 127 ASN A N     1 
ATOM   856   C  CA    . ASN A 1 127 ? 229.859 225.432 184.819 1.00 11.88  ? 127 ASN A CA    1 
ATOM   857   C  C     . ASN A 1 127 ? 230.871 224.398 184.326 1.00 11.22  ? 127 ASN A C     1 
ATOM   858   O  O     . ASN A 1 127 ? 231.479 224.566 183.271 1.00 12.18  ? 127 ASN A O     1 
ATOM   859   C  CB    . ASN A 1 127 ? 230.472 226.342 185.873 1.00 12.30  ? 127 ASN A CB    1 
ATOM   860   C  CG    . ASN A 1 127 ? 231.657 227.108 185.354 1.00 12.92  ? 127 ASN A CG    1 
ATOM   861   O  OD1   . ASN A 1 127 ? 231.626 227.584 184.217 1.00 13.33  ? 127 ASN A OD1   1 
ATOM   862   N  ND2   . ASN A 1 127 ? 232.698 227.206 186.168 1.00 13.25  ? 127 ASN A ND2   1 
ATOM   863   N  N     . VAL A 1 128 ? 231.082 223.339 185.102 1.00 10.97  ? 128 VAL A N     1 
ATOM   864   C  CA    . VAL A 1 128 ? 231.983 222.285 184.689 1.00 11.00  ? 128 VAL A CA    1 
ATOM   865   C  C     . VAL A 1 128 ? 231.419 221.562 183.464 1.00 10.64  ? 128 VAL A C     1 
ATOM   866   O  O     . VAL A 1 128 ? 232.155 221.285 182.518 1.00 10.70  ? 128 VAL A O     1 
ATOM   867   C  CB    . VAL A 1 128 ? 232.258 221.319 185.854 1.00 11.35  ? 128 VAL A CB    1 
ATOM   868   C  CG1   . VAL A 1 128 ? 233.062 220.104 185.397 1.00 11.51  ? 128 VAL A CG1   1 
ATOM   869   C  CG2   . VAL A 1 128 ? 232.985 222.050 186.975 1.00 11.34  ? 128 VAL A CG2   1 
ATOM   870   N  N     . ILE A 1 129 ? 230.119 221.250 183.482 1.00 10.96  ? 129 ILE A N     1 
ATOM   871   C  CA    . ILE A 1 129 ? 229.507 220.492 182.401 1.00 11.37  ? 129 ILE A CA    1 
ATOM   872   C  C     . ILE A 1 129 ? 229.686 221.233 181.076 1.00 12.23  ? 129 ILE A C     1 
ATOM   873   O  O     . ILE A 1 129 ? 230.108 220.638 180.082 1.00 13.04  ? 129 ILE A O     1 
ATOM   874   C  CB    . ILE A 1 129 ? 228.018 220.222 182.688 1.00 11.68  ? 129 ILE A CB    1 
ATOM   875   C  CG1   . ILE A 1 129 ? 227.868 219.128 183.752 1.00 12.00  ? 129 ILE A CG1   1 
ATOM   876   C  CG2   . ILE A 1 129 ? 227.269 219.871 181.401 1.00 11.28  ? 129 ILE A CG2   1 
ATOM   877   C  CD1   . ILE A 1 129 ? 226.450 218.945 184.236 1.00 12.48  ? 129 ILE A CD1   1 
ATOM   878   N  N     . ARG A 1 130 ? 229.342 222.519 181.046 1.00 12.44  ? 130 ARG A N     1 
ATOM   879   C  CA    . ARG A 1 130 ? 229.334 223.258 179.795 1.00 14.00  ? 130 ARG A CA    1 
ATOM   880   C  C     . ARG A 1 130 ? 230.746 223.415 179.233 1.00 14.10  ? 130 ARG A C     1 
ATOM   881   O  O     . ARG A 1 130 ? 230.905 223.504 178.021 1.00 15.20  ? 130 ARG A O     1 
ATOM   882   C  CB    . ARG A 1 130 ? 228.666 224.628 179.956 1.00 14.51  ? 130 ARG A CB    1 
ATOM   883   C  CG    . ARG A 1 130 ? 229.583 225.688 180.538 1.00 15.80  ? 130 ARG A CG    1 
ATOM   884   C  CD    . ARG A 1 130 ? 228.810 226.814 181.175 1.00 15.76  ? 130 ARG A CD    1 
ATOM   885   N  NE    . ARG A 1 130 ? 229.746 227.757 181.789 1.00 16.59  ? 130 ARG A NE    1 
ATOM   886   C  CZ    . ARG A 1 130 ? 230.460 228.648 181.130 1.00 17.87  ? 130 ARG A CZ    1 
ATOM   887   N  NH1   . ARG A 1 130 ? 230.275 228.849 179.837 1.00 18.33  ? 130 ARG A NH1   1 
ATOM   888   N  NH2   . ARG A 1 130 ? 231.364 229.359 181.771 1.00 18.88  ? 130 ARG A NH2   1 
ATOM   889   N  N     . LEU A 1 131 ? 231.764 223.449 180.102 1.00 14.18  ? 131 LEU A N     1 
ATOM   890   C  CA    . LEU A 1 131 ? 233.141 223.630 179.656 1.00 13.96  ? 131 LEU A CA    1 
ATOM   891   C  C     . LEU A 1 131 ? 233.802 222.306 179.295 1.00 13.99  ? 131 LEU A C     1 
ATOM   892   O  O     . LEU A 1 131 ? 234.573 222.252 178.342 1.00 15.79  ? 131 LEU A O     1 
ATOM   893   C  CB    . LEU A 1 131 ? 233.950 224.367 180.719 1.00 14.02  ? 131 LEU A CB    1 
ATOM   894   C  CG    . LEU A 1 131 ? 233.555 225.830 180.938 1.00 14.12  ? 131 LEU A CG    1 
ATOM   895   C  CD1   . LEU A 1 131 ? 234.289 226.404 182.133 1.00 14.26  ? 131 LEU A CD1   1 
ATOM   896   C  CD2   . LEU A 1 131 ? 233.809 226.662 179.686 1.00 14.75  ? 131 LEU A CD2   1 
ATOM   897   N  N     . VAL A 1 132 ? 233.528 221.238 180.046 1.00 13.99  ? 132 VAL A N     1 
ATOM   898   C  CA    . VAL A 1 132 ? 234.111 219.949 179.723 1.00 15.18  ? 132 VAL A CA    1 
ATOM   899   C  C     . VAL A 1 132 ? 233.473 219.379 178.453 1.00 15.29  ? 132 VAL A C     1 
ATOM   900   O  O     . VAL A 1 132 ? 234.103 218.601 177.737 1.00 16.25  ? 132 VAL A O     1 
ATOM   901   C  CB    . VAL A 1 132 ? 233.996 218.964 180.895 1.00 15.62  ? 132 VAL A CB    1 
ATOM   902   C  CG1   . VAL A 1 132 ? 232.555 218.526 181.123 1.00 15.51  ? 132 VAL A CG1   1 
ATOM   903   C  CG2   . VAL A 1 132 ? 234.892 217.761 180.669 1.00 16.69  ? 132 VAL A CG2   1 
ATOM   904   N  N     . ALA A 1 133 ? 232.208 219.727 178.187 1.00 16.00  ? 133 ALA A N     1 
ATOM   905   C  CA    . ALA A 1 133 ? 231.546 219.274 176.973 1.00 16.96  ? 133 ALA A CA    1 
ATOM   906   C  C     . ALA A 1 133 ? 232.290 219.789 175.744 1.00 18.58  ? 133 ALA A C     1 
ATOM   907   O  O     . ALA A 1 133 ? 232.445 219.070 174.763 1.00 18.58  ? 133 ALA A O     1 
ATOM   908   C  CB    . ALA A 1 133 ? 230.095 219.693 176.954 1.00 17.21  ? 133 ALA A CB    1 
ATOM   909   N  N     . GLY A 1 134 ? 232.732 221.047 175.788 1.00 20.39  ? 134 GLY A N     1 
ATOM   910   C  CA    . GLY A 1 134 ? 233.539 221.607 174.718 1.00 21.96  ? 134 GLY A CA    1 
ATOM   911   C  C     . GLY A 1 134 ? 234.858 220.857 174.556 1.00 22.74  ? 134 GLY A C     1 
ATOM   912   O  O     . GLY A 1 134 ? 235.289 220.598 173.434 1.00 26.35  ? 134 GLY A O     1 
ATOM   913   N  N     . GLU A 1 135 ? 235.489 220.496 175.677 1.00 23.10  ? 135 GLU A N     1 
ATOM   914   C  CA    . GLU A 1 135 ? 236.708 219.705 175.629 1.00 22.99  ? 135 GLU A CA    1 
ATOM   915   C  C     . GLU A 1 135 ? 236.429 218.307 175.083 1.00 21.25  ? 135 GLU A C     1 
ATOM   916   O  O     . GLU A 1 135 ? 237.178 217.801 174.257 1.00 21.77  ? 135 GLU A O     1 
ATOM   917   C  CB    . GLU A 1 135 ? 237.353 219.632 177.010 1.00 27.57  ? 135 GLU A CB    1 
ATOM   918   C  CG    . GLU A 1 135 ? 237.887 220.980 177.480 1.00 32.77  ? 135 GLU A CG    1 
ATOM   919   C  CD    . GLU A 1 135 ? 238.706 221.721 176.437 1.00 39.17  ? 135 GLU A CD    1 
ATOM   920   O  OE1   . GLU A 1 135 ? 238.155 222.689 175.857 1.00 42.10  ? 135 GLU A OE1   1 
ATOM   921   O  OE2   . GLU A 1 135 ? 239.840 221.276 176.156 1.00 44.32  ? 135 GLU A OE2   1 
ATOM   922   N  N     . MET A 1 136 ? 235.354 217.672 175.550 1.00 18.20  ? 136 MET A N     1 
ATOM   923   C  CA    . MET A 1 136 ? 234.982 216.350 175.073 1.00 17.05  ? 136 MET A CA    1 
ATOM   924   C  C     . MET A 1 136 ? 234.576 216.388 173.597 1.00 17.16  ? 136 MET A C     1 
ATOM   925   O  O     . MET A 1 136 ? 234.766 215.409 172.888 1.00 17.07  ? 136 MET A O     1 
ATOM   926   C  CB    . MET A 1 136 ? 233.820 215.780 175.900 1.00 15.62  ? 136 MET A CB    1 
ATOM   927   C  CG    . MET A 1 136 ? 234.244 215.132 177.197 1.00 15.26  ? 136 MET A CG    1 
ATOM   928   S  SD    . MET A 1 136 ? 232.851 214.969 178.324 1.00 14.28  ? 136 MET A SD    1 
ATOM   929   C  CE    . MET A 1 136 ? 233.688 214.335 179.780 1.00 14.40  ? 136 MET A CE    1 
ATOM   930   N  N     . GLY A 1 137 ? 233.995 217.500 173.143 1.00 18.56  ? 137 GLY A N     1 
ATOM   931   C  CA    . GLY A 1 137 ? 233.566 217.620 171.763 1.00 20.10  ? 137 GLY A CA    1 
ATOM   932   C  C     . GLY A 1 137 ? 234.734 217.510 170.782 1.00 23.03  ? 137 GLY A C     1 
ATOM   933   O  O     . GLY A 1 137 ? 234.536 217.115 169.635 1.00 27.25  ? 137 GLY A O     1 
ATOM   934   N  N     . GLN A 1 138 ? 235.947 217.844 171.227 1.00 25.00  ? 138 GLN A N     1 
ATOM   935   C  CA    . GLN A 1 138 ? 237.122 217.739 170.374 1.00 27.37  ? 138 GLN A CA    1 
ATOM   936   C  C     . GLN A 1 138 ? 237.573 216.291 170.192 1.00 26.50  ? 138 GLN A C     1 
ATOM   937   O  O     . GLN A 1 138 ? 238.369 216.020 169.303 1.00 28.64  ? 138 GLN A O     1 
ATOM   938   C  CB    . GLN A 1 138 ? 238.281 218.550 170.946 1.00 30.98  ? 138 GLN A CB    1 
ATOM   939   C  CG    . GLN A 1 138 ? 238.036 220.055 170.990 1.00 36.69  ? 138 GLN A CG    1 
ATOM   940   C  CD    . GLN A 1 138 ? 237.512 220.624 169.689 1.00 44.40  ? 138 GLN A CD    1 
ATOM   941   O  OE1   . GLN A 1 138 ? 236.301 220.624 169.439 1.00 45.79  ? 138 GLN A OE1   1 
ATOM   942   N  NE2   . GLN A 1 138 ? 238.416 221.119 168.852 1.00 48.58  ? 138 GLN A NE2   1 
ATOM   943   N  N     . ASN A 1 139 ? 237.082 215.368 171.022 1.00 25.04  ? 139 ASN A N     1 
ATOM   944   C  CA    . ASN A 1 139 ? 237.470 213.974 170.914 1.00 24.78  ? 139 ASN A CA    1 
ATOM   945   C  C     . ASN A 1 139 ? 236.884 213.363 169.641 1.00 26.48  ? 139 ASN A C     1 
ATOM   946   O  O     . ASN A 1 139 ? 235.760 213.662 169.247 1.00 26.21  ? 139 ASN A O     1 
ATOM   947   C  CB    . ASN A 1 139 ? 237.021 213.159 172.123 1.00 24.78  ? 139 ASN A CB    1 
ATOM   948   C  CG    . ASN A 1 139 ? 237.685 213.596 173.404 1.00 23.94  ? 139 ASN A CG    1 
ATOM   949   O  OD1   . ASN A 1 139 ? 238.770 214.186 173.379 1.00 23.61  ? 139 ASN A OD1   1 
ATOM   950   N  ND2   . ASN A 1 139 ? 237.052 213.301 174.531 1.00 21.76  ? 139 ASN A ND2   1 
ATOM   951   N  N     . GLU A 1 140 ? 237.661 212.480 169.013 1.00 28.06  ? 140 GLU A N     1 
ATOM   952   C  CA    . GLU A 1 140 ? 237.127 211.637 167.966 1.00 31.39  ? 140 GLU A CA    1 
ATOM   953   C  C     . GLU A 1 140 ? 236.211 210.598 168.597 1.00 29.22  ? 140 GLU A C     1 
ATOM   954   O  O     . GLU A 1 140 ? 236.566 209.972 169.592 1.00 31.84  ? 140 GLU A O     1 
ATOM   955   C  CB    . GLU A 1 140 ? 238.247 210.951 167.191 1.00 35.81  ? 140 GLU A CB    1 
ATOM   956   C  CG    . GLU A 1 140 ? 239.017 211.901 166.283 1.00 42.10  ? 140 GLU A CG    1 
ATOM   957   C  CD    . GLU A 1 140 ? 238.199 212.411 165.112 1.00 49.15  ? 140 GLU A CD    1 
ATOM   958   O  OE1   . GLU A 1 140 ? 238.388 213.593 164.742 1.00 53.29  ? 140 GLU A OE1   1 
ATOM   959   O  OE2   . GLU A 1 140 ? 237.376 211.637 164.567 1.00 52.33  ? 140 GLU A OE2   1 
ATOM   960   N  N     . PRO A 1 141 ? 235.007 210.370 168.040 1.00 27.99  ? 141 PRO A N     1 
ATOM   961   C  CA    . PRO A 1 141 ? 234.110 209.372 168.609 1.00 28.55  ? 141 PRO A CA    1 
ATOM   962   C  C     . PRO A 1 141 ? 234.734 207.979 168.564 1.00 30.54  ? 141 PRO A C     1 
ATOM   963   O  O     . PRO A 1 141 ? 235.454 207.641 167.627 1.00 32.26  ? 141 PRO A O     1 
ATOM   964   C  CB    . PRO A 1 141 ? 232.852 209.466 167.746 1.00 27.88  ? 141 PRO A CB    1 
ATOM   965   C  CG    . PRO A 1 141 ? 232.969 210.779 167.034 1.00 28.59  ? 141 PRO A CG    1 
ATOM   966   C  CD    . PRO A 1 141 ? 234.448 211.038 166.854 1.00 28.22  ? 141 PRO A CD    1 
ATOM   967   N  N     . ASP A 1 142 ? 234.407 207.160 169.565 1.00 31.13  ? 142 ASP A N     1 
ATOM   968   C  CA    . ASP A 1 142 ? 234.824 205.768 169.586 1.00 33.67  ? 142 ASP A CA    1 
ATOM   969   C  C     . ASP A 1 142 ? 233.961 204.967 168.609 1.00 34.76  ? 142 ASP A C     1 
ATOM   970   O  O     . ASP A 1 142 ? 233.176 205.529 167.848 1.00 33.69  ? 142 ASP A O     1 
ATOM   971   C  CB    . ASP A 1 142 ? 234.784 205.213 171.000 1.00 35.62  ? 142 ASP A CB    1 
ATOM   972   C  CG    . ASP A 1 142 ? 233.401 205.197 171.639 1.00 38.38  ? 142 ASP A CG    1 
ATOM   973   O  OD1   . ASP A 1 142 ? 233.344 205.202 172.883 1.00 41.59  ? 142 ASP A OD1   1 
ATOM   974   O  OD2   . ASP A 1 142 ? 232.386 205.262 170.899 1.00 38.53  ? 142 ASP A OD2   1 
ATOM   975   N  N     . GLN A 1 143 ? 234.109 203.640 168.612 1.00 39.76  ? 143 GLN A N     1 
ATOM   976   C  CA    . GLN A 1 143 ? 233.363 202.805 167.677 1.00 43.92  ? 143 GLN A CA    1 
ATOM   977   C  C     . GLN A 1 143 ? 231.856 202.940 167.903 1.00 40.79  ? 143 GLN A C     1 
ATOM   978   O  O     . GLN A 1 143 ? 231.065 202.810 166.965 1.00 42.00  ? 143 GLN A O     1 
ATOM   979   C  CB    . GLN A 1 143 ? 233.774 201.340 167.754 1.00 53.42  ? 143 GLN A CB    1 
ATOM   980   C  CG    . GLN A 1 143 ? 233.551 200.710 169.122 1.00 61.61  ? 143 GLN A CG    1 
ATOM   981   C  CD    . GLN A 1 143 ? 234.709 200.928 170.075 1.00 69.28  ? 143 GLN A CD    1 
ATOM   982   O  OE1   . GLN A 1 143 ? 235.622 201.727 169.835 1.00 72.39  ? 143 GLN A OE1   1 
ATOM   983   N  NE2   . GLN A 1 143 ? 234.670 200.215 171.192 1.00 75.82  ? 143 GLN A NE2   1 
ATOM   984   N  N     . GLY A 1 144 ? 231.458 203.220 169.154 1.00 36.46  ? 144 GLY A N     1 
ATOM   985   C  CA    . GLY A 1 144 ? 230.058 203.416 169.496 1.00 31.94  ? 144 GLY A CA    1 
ATOM   986   C  C     . GLY A 1 144 ? 229.583 204.859 169.329 1.00 28.97  ? 144 GLY A C     1 
ATOM   987   O  O     . GLY A 1 144 ? 228.433 205.166 169.638 1.00 30.82  ? 144 GLY A O     1 
ATOM   988   N  N     . GLY A 1 145 ? 230.448 205.748 168.835 1.00 24.87  ? 145 GLY A N     1 
ATOM   989   C  CA    . GLY A 1 145 ? 230.059 207.126 168.601 1.00 23.55  ? 145 GLY A CA    1 
ATOM   990   C  C     . GLY A 1 145 ? 230.149 208.004 169.850 1.00 21.64  ? 145 GLY A C     1 
ATOM   991   O  O     . GLY A 1 145 ? 229.676 209.138 169.827 1.00 20.37  ? 145 GLY A O     1 
ATOM   992   N  N     . GLN A 1 146 ? 230.763 207.498 170.925 1.00 20.90  ? 146 GLN A N     1 
ATOM   993   C  CA    . GLN A 1 146 ? 230.799 208.227 172.186 1.00 19.65  ? 146 GLN A CA    1 
ATOM   994   C  C     . GLN A 1 146 ? 232.051 209.091 172.259 1.00 17.85  ? 146 GLN A C     1 
ATOM   995   O  O     . GLN A 1 146 ? 233.144 208.628 171.963 1.00 18.65  ? 146 GLN A O     1 
ATOM   996   C  CB    . GLN A 1 146 ? 230.742 207.252 173.360 1.00 19.98  ? 146 GLN A CB    1 
ATOM   997   C  CG    . GLN A 1 146 ? 230.761 207.925 174.724 1.00 20.75  ? 146 GLN A CG    1 
ATOM   998   C  CD    . GLN A 1 146 ? 230.725 206.920 175.847 1.00 21.53  ? 146 GLN A CD    1 
ATOM   999   O  OE1   . GLN A 1 146 ? 229.663 206.405 176.198 1.00 21.10  ? 146 GLN A OE1   1 
ATOM   1000  N  NE2   . GLN A 1 146 ? 231.885 206.648 176.426 1.00 22.19  ? 146 GLN A NE2   1 
ATOM   1001  N  N     . ARG A 1 147 ? 231.880 210.341 172.692 1.00 16.17  ? 147 ARG A N     1 
ATOM   1002  C  CA    . ARG A 1 147 ? 232.988 211.262 172.880 1.00 15.55  ? 147 ARG A CA    1 
ATOM   1003  C  C     . ARG A 1 147 ? 233.314 211.473 174.356 1.00 13.91  ? 147 ARG A C     1 
ATOM   1004  O  O     . ARG A 1 147 ? 234.398 211.936 174.688 1.00 14.96  ? 147 ARG A O     1 
ATOM   1005  C  CB    . ARG A 1 147 ? 232.675 212.622 172.255 1.00 16.68  ? 147 ARG A CB    1 
ATOM   1006  C  CG    . ARG A 1 147 ? 232.799 212.664 170.741 1.00 18.46  ? 147 ARG A CG    1 
ATOM   1007  C  CD    . ARG A 1 147 ? 232.655 214.071 170.232 1.00 21.15  ? 147 ARG A CD    1 
ATOM   1008  N  NE    . ARG A 1 147 ? 232.891 214.178 168.790 1.00 24.68  ? 147 ARG A NE    1 
ATOM   1009  C  CZ    . ARG A 1 147 ? 231.975 214.008 167.850 1.00 27.24  ? 147 ARG A CZ    1 
ATOM   1010  N  NH1   . ARG A 1 147 ? 230.725 213.729 168.164 1.00 27.78  ? 147 ARG A NH1   1 
ATOM   1011  N  NH2   . ARG A 1 147 ? 232.305 214.114 166.581 1.00 30.91  ? 147 ARG A NH2   1 
ATOM   1012  N  N     . GLY A 1 148 ? 232.383 211.200 175.266 1.00 12.04  ? 148 GLY A N     1 
ATOM   1013  C  CA    . GLY A 1 148 ? 232.651 211.426 176.672 1.00 11.55  ? 148 GLY A CA    1 
ATOM   1014  C  C     . GLY A 1 148 ? 231.472 211.011 177.539 1.00 10.86  ? 148 GLY A C     1 
ATOM   1015  O  O     . GLY A 1 148 ? 230.385 210.752 177.038 1.00 10.54  ? 148 GLY A O     1 
ATOM   1016  N  N     . VAL A 1 149 ? 231.722 210.974 178.846 1.00 10.81  ? 149 VAL A N     1 
ATOM   1017  C  CA    . VAL A 1 149 ? 230.703 210.674 179.836 1.00 10.68  ? 149 VAL A CA    1 
ATOM   1018  C  C     . VAL A 1 149 ? 230.817 211.716 180.941 1.00 9.58   ? 149 VAL A C     1 
ATOM   1019  O  O     . VAL A 1 149 ? 231.909 211.981 181.442 1.00 9.53   ? 149 VAL A O     1 
ATOM   1020  C  CB    . VAL A 1 149 ? 230.854 209.259 180.425 1.00 11.33  ? 149 VAL A CB    1 
ATOM   1021  C  CG1   . VAL A 1 149 ? 229.670 208.914 181.314 1.00 11.53  ? 149 VAL A CG1   1 
ATOM   1022  C  CG2   . VAL A 1 149 ? 231.028 208.212 179.337 1.00 12.32  ? 149 VAL A CG2   1 
ATOM   1023  N  N     . ILE A 1 150 ? 229.676 212.301 181.311 1.00 9.02   ? 150 ILE A N     1 
ATOM   1024  C  CA    . ILE A 1 150 ? 229.612 213.224 182.428 1.00 9.07   ? 150 ILE A CA    1 
ATOM   1025  C  C     . ILE A 1 150 ? 228.725 212.617 183.505 1.00 8.58   ? 150 ILE A C     1 
ATOM   1026  O  O     . ILE A 1 150 ? 227.581 212.252 183.236 1.00 8.54   ? 150 ILE A O     1 
ATOM   1027  C  CB    . ILE A 1 150 ? 229.089 214.597 181.989 1.00 9.70   ? 150 ILE A CB    1 
ATOM   1028  C  CG1   . ILE A 1 150 ? 229.986 215.219 180.924 1.00 10.24  ? 150 ILE A CG1   1 
ATOM   1029  C  CG2   . ILE A 1 150 ? 228.925 215.518 183.197 1.00 10.18  ? 150 ILE A CG2   1 
ATOM   1030  C  CD1   . ILE A 1 150 ? 229.384 216.456 180.278 1.00 10.45  ? 150 ILE A CD1   1 
ATOM   1031  N  N     . ILE A 1 151 ? 229.272 212.519 184.719 1.00 8.42   ? 151 ILE A N     1 
ATOM   1032  C  CA    . ILE A 1 151 ? 228.557 211.977 185.859 1.00 8.61   ? 151 ILE A CA    1 
ATOM   1033  C  C     . ILE A 1 151 ? 228.454 213.060 186.918 1.00 8.79   ? 151 ILE A C     1 
ATOM   1034  O  O     . ILE A 1 151 ? 229.463 213.601 187.358 1.00 9.26   ? 151 ILE A O     1 
ATOM   1035  C  CB    . ILE A 1 151 ? 229.243 210.713 186.393 1.00 9.04   ? 151 ILE A CB    1 
ATOM   1036  C  CG1   . ILE A 1 151 ? 229.240 209.615 185.345 1.00 9.49   ? 151 ILE A CG1   1 
ATOM   1037  C  CG2   . ILE A 1 151 ? 228.587 210.243 187.695 1.00 9.09   ? 151 ILE A CG2   1 
ATOM   1038  C  CD1   . ILE A 1 151 ? 230.461 208.736 185.384 1.00 10.00  ? 151 ILE A CD1   1 
ATOM   1039  N  N     . ASN A 1 152 ? 227.217 213.354 187.322 1.00 8.91   ? 152 ASN A N     1 
ATOM   1040  C  CA    . ASN A 1 152 ? 226.944 214.367 188.323 1.00 9.47   ? 152 ASN A CA    1 
ATOM   1041  C  C     . ASN A 1 152 ? 226.541 213.704 189.627 1.00 9.46   ? 152 ASN A C     1 
ATOM   1042  O  O     . ASN A 1 152 ? 226.102 212.555 189.655 1.00 9.17   ? 152 ASN A O     1 
ATOM   1043  C  CB    . ASN A 1 152 ? 225.839 215.312 187.872 1.00 10.30  ? 152 ASN A CB    1 
ATOM   1044  C  CG    . ASN A 1 152 ? 226.047 215.778 186.457 1.00 11.03  ? 152 ASN A CG    1 
ATOM   1045  O  OD1   . ASN A 1 152 ? 227.072 216.393 186.156 1.00 12.17  ? 152 ASN A OD1   1 
ATOM   1046  N  ND2   . ASN A 1 152 ? 225.100 215.494 185.580 1.00 12.17  ? 152 ASN A ND2   1 
ATOM   1047  N  N     . THR A 1 153 ? 226.701 214.457 190.714 1.00 10.10  ? 153 THR A N     1 
ATOM   1048  C  CA    . THR A 1 153 ? 226.331 213.991 192.037 1.00 10.60  ? 153 THR A CA    1 
ATOM   1049  C  C     . THR A 1 153 ? 225.154 214.826 192.526 1.00 10.78  ? 153 THR A C     1 
ATOM   1050  O  O     . THR A 1 153 ? 225.320 215.984 192.915 1.00 11.40  ? 153 THR A O     1 
ATOM   1051  C  CB    . THR A 1 153 ? 227.510 214.073 192.995 1.00 11.00  ? 153 THR A CB    1 
ATOM   1052  O  OG1   . THR A 1 153 ? 228.630 213.401 192.414 1.00 11.83  ? 153 THR A OG1   1 
ATOM   1053  C  CG2   . THR A 1 153 ? 227.181 213.437 194.330 1.00 11.03  ? 153 THR A CG2   1 
ATOM   1054  N  N     . ALA A 1 154 ? 223.969 214.214 192.523 1.00 10.78  ? 154 ALA A N     1 
ATOM   1055  C  CA    . ALA A 1 154 ? 222.807 214.753 193.211 1.00 10.97  ? 154 ALA A CA    1 
ATOM   1056  C  C     . ALA A 1 154 ? 222.817 214.224 194.641 1.00 11.56  ? 154 ALA A C     1 
ATOM   1057  O  O     . ALA A 1 154 ? 223.860 213.857 195.162 1.00 12.92  ? 154 ALA A O     1 
ATOM   1058  C  CB    . ALA A 1 154 ? 221.529 214.378 192.484 1.00 10.91  ? 154 ALA A CB    1 
ATOM   1059  N  N     . SER A 1 155 ? 221.658 214.211 195.295 1.00 11.80  ? 155 SER A N     1 
ATOM   1060  C  CA    . SER A 1 155 ? 221.510 213.563 196.588 1.00 11.24  ? 155 SER A CA    1 
ATOM   1061  C  C     . SER A 1 155 ? 220.106 212.971 196.673 1.00 10.86  ? 155 SER A C     1 
ATOM   1062  O  O     . SER A 1 155 ? 219.212 213.355 195.922 1.00 10.74  ? 155 SER A O     1 
ATOM   1063  C  CB    . SER A 1 155 ? 221.739 214.562 197.719 1.00 11.98  ? 155 SER A CB    1 
ATOM   1064  O  OG    . SER A 1 155 ? 221.588 213.922 198.986 1.00 12.63  ? 155 SER A OG    1 
ATOM   1065  N  N     . VAL A 1 156 ? 219.903 212.062 197.620 1.00 10.92  ? 156 VAL A N     1 
ATOM   1066  C  CA    . VAL A 1 156 ? 218.553 211.647 197.966 1.00 11.48  ? 156 VAL A CA    1 
ATOM   1067  C  C     . VAL A 1 156 ? 217.746 212.842 198.487 1.00 9.98   ? 156 VAL A C     1 
ATOM   1068  O  O     . VAL A 1 156 ? 216.522 212.814 198.490 1.00 10.23  ? 156 VAL A O     1 
ATOM   1069  C  CB    . VAL A 1 156 ? 218.562 210.495 198.982 1.00 12.47  ? 156 VAL A CB    1 
ATOM   1070  C  CG1   . VAL A 1 156 ? 219.170 209.246 198.337 1.00 13.60  ? 156 VAL A CG1   1 
ATOM   1071  C  CG2   . VAL A 1 156 ? 219.254 210.887 200.272 1.00 13.43  ? 156 VAL A CG2   1 
ATOM   1072  N  N     . ALA A 1 157 ? 218.427 213.890 198.951 1.00 9.70   ? 157 ALA A N     1 
ATOM   1073  C  CA    . ALA A 1 157 ? 217.756 215.116 199.363 1.00 9.77   ? 157 ALA A CA    1 
ATOM   1074  C  C     . ALA A 1 157 ? 217.016 215.770 198.201 1.00 9.59   ? 157 ALA A C     1 
ATOM   1075  O  O     . ALA A 1 157 ? 216.102 216.558 198.435 1.00 10.13  ? 157 ALA A O     1 
ATOM   1076  C  CB    . ALA A 1 157 ? 218.746 216.089 199.968 1.00 10.20  ? 157 ALA A CB    1 
ATOM   1077  N  N     . ALA A 1 158 ? 217.371 215.437 196.957 1.00 9.35   ? 158 ALA A N     1 
ATOM   1078  C  CA    . ALA A 1 158 ? 216.631 215.942 195.810 1.00 10.10  ? 158 ALA A CA    1 
ATOM   1079  C  C     . ALA A 1 158 ? 215.209 215.367 195.770 1.00 10.81  ? 158 ALA A C     1 
ATOM   1080  O  O     . ALA A 1 158 ? 214.343 215.938 195.118 1.00 11.11  ? 158 ALA A O     1 
ATOM   1081  C  CB    . ALA A 1 158 ? 217.375 215.643 194.528 1.00 9.96   ? 158 ALA A CB    1 
ATOM   1082  N  N     . PHE A 1 159 ? 214.976 214.241 196.449 1.00 11.62  ? 159 PHE A N     1 
ATOM   1083  C  CA    . PHE A 1 159 ? 213.687 213.566 196.422 1.00 13.62  ? 159 PHE A CA    1 
ATOM   1084  C  C     . PHE A 1 159 ? 212.986 213.632 197.777 1.00 14.80  ? 159 PHE A C     1 
ATOM   1085  O  O     . PHE A 1 159 ? 211.780 213.882 197.825 1.00 17.98  ? 159 PHE A O     1 
ATOM   1086  C  CB    . PHE A 1 159 ? 213.852 212.098 196.008 1.00 14.59  ? 159 PHE A CB    1 
ATOM   1087  C  CG    . PHE A 1 159 ? 214.585 211.951 194.694 1.00 14.73  ? 159 PHE A CG    1 
ATOM   1088  C  CD1   . PHE A 1 159 ? 214.001 212.363 193.499 1.00 16.39  ? 159 PHE A CD1   1 
ATOM   1089  C  CD2   . PHE A 1 159 ? 215.864 211.422 194.666 1.00 15.84  ? 159 PHE A CD2   1 
ATOM   1090  C  CE1   . PHE A 1 159 ? 214.688 212.236 192.300 1.00 16.61  ? 159 PHE A CE1   1 
ATOM   1091  C  CE2   . PHE A 1 159 ? 216.544 211.285 193.468 1.00 16.37  ? 159 PHE A CE2   1 
ATOM   1092  C  CZ    . PHE A 1 159 ? 215.956 211.698 192.286 1.00 16.40  ? 159 PHE A CZ    1 
ATOM   1093  N  N     . GLU A 1 160 ? 213.722 213.383 198.864 1.00 16.06  ? 160 GLU A N     1 
ATOM   1094  C  CA    . GLU A 1 160 ? 213.184 213.575 200.199 1.00 18.42  ? 160 GLU A CA    1 
ATOM   1095  C  C     . GLU A 1 160 ? 214.155 214.403 201.028 1.00 15.76  ? 160 GLU A C     1 
ATOM   1096  O  O     . GLU A 1 160 ? 214.927 213.869 201.798 1.00 18.55  ? 160 GLU A O     1 
ATOM   1097  C  CB    . GLU A 1 160 ? 212.774 212.273 200.881 1.00 23.95  ? 160 GLU A CB    1 
ATOM   1098  C  CG    . GLU A 1 160 ? 213.896 211.273 201.106 1.00 28.80  ? 160 GLU A CG    1 
ATOM   1099  C  CD    . GLU A 1 160 ? 214.185 210.347 199.950 1.00 32.52  ? 160 GLU A CD    1 
ATOM   1100  O  OE1   . GLU A 1 160 ? 213.704 210.629 198.839 1.00 37.05  ? 160 GLU A OE1   1 
ATOM   1101  O  OE2   . GLU A 1 160 ? 214.897 209.359 200.178 1.00 32.89  ? 160 GLU A OE2   1 
ATOM   1102  N  N     . GLY A 1 161 ? 214.118 215.725 200.852 1.00 13.38  ? 161 GLY A N     1 
ATOM   1103  C  CA    . GLY A 1 161 ? 214.960 216.606 201.644 1.00 11.82  ? 161 GLY A CA    1 
ATOM   1104  C  C     . GLY A 1 161 ? 214.405 216.737 203.060 1.00 11.27  ? 161 GLY A C     1 
ATOM   1105  O  O     . GLY A 1 161 ? 213.197 216.812 203.264 1.00 10.99  ? 161 GLY A O     1 
ATOM   1106  N  N     . GLN A 1 162 ? 215.311 216.732 204.037 1.00 11.47  ? 162 GLN A N     1 
ATOM   1107  C  CA    . GLN A 1 162 ? 214.928 216.804 205.429 1.00 12.37  ? 162 GLN A CA    1 
ATOM   1108  C  C     . GLN A 1 162 ? 214.672 218.253 205.840 1.00 11.64  ? 162 GLN A C     1 
ATOM   1109  O  O     . GLN A 1 162 ? 214.916 219.193 205.090 1.00 11.23  ? 162 GLN A O     1 
ATOM   1110  C  CB    . GLN A 1 162 ? 216.066 216.223 206.262 1.00 13.47  ? 162 GLN A CB    1 
ATOM   1111  C  CG    . GLN A 1 162 ? 216.309 214.741 206.052 1.00 15.82  ? 162 GLN A CG    1 
ATOM   1112  C  CD    . GLN A 1 162 ? 217.100 214.164 207.200 1.00 17.61  ? 162 GLN A CD    1 
ATOM   1113  O  OE1   . GLN A 1 162 ? 218.333 214.259 207.232 1.00 19.71  ? 162 GLN A OE1   1 
ATOM   1114  N  NE2   . GLN A 1 162 ? 216.386 213.564 208.146 1.00 18.55  ? 162 GLN A NE2   1 
ATOM   1115  N  N     . VAL A 1 163 ? 214.197 218.418 207.076 1.00 12.03  ? 163 VAL A N     1 
ATOM   1116  C  CA    . VAL A 1 163 ? 214.131 219.729 207.693 1.00 11.68  ? 163 VAL A CA    1 
ATOM   1117  C  C     . VAL A 1 163 ? 215.527 220.335 207.728 1.00 10.78  ? 163 VAL A C     1 
ATOM   1118  O  O     . VAL A 1 163 ? 216.495 219.701 208.134 1.00 10.54  ? 163 VAL A O     1 
ATOM   1119  C  CB    . VAL A 1 163 ? 213.529 219.615 209.101 1.00 12.27  ? 163 VAL A CB    1 
ATOM   1120  C  CG1   . VAL A 1 163 ? 213.755 220.880 209.927 1.00 12.51  ? 163 VAL A CG1   1 
ATOM   1121  C  CG2   . VAL A 1 163 ? 212.058 219.234 209.036 1.00 12.23  ? 163 VAL A CG2   1 
ATOM   1122  N  N     . GLY A 1 164 ? 215.622 221.593 207.308 1.00 10.59  ? 164 GLY A N     1 
ATOM   1123  C  CA    . GLY A 1 164 ? 216.892 222.296 207.288 1.00 10.44  ? 164 GLY A CA    1 
ATOM   1124  C  C     . GLY A 1 164 ? 217.683 222.077 205.993 1.00 10.41  ? 164 GLY A C     1 
ATOM   1125  O  O     . GLY A 1 164 ? 218.768 222.635 205.849 1.00 10.80  ? 164 GLY A O     1 
ATOM   1126  N  N     . GLN A 1 165 ? 217.140 221.313 205.034 1.00 10.49  ? 165 GLN A N     1 
ATOM   1127  C  CA    . GLN A 1 165 ? 217.891 220.958 203.833 1.00 11.08  ? 165 GLN A CA    1 
ATOM   1128  C  C     . GLN A 1 165 ? 217.346 221.655 202.584 1.00 9.82   ? 165 GLN A C     1 
ATOM   1129  O  O     . GLN A 1 165 ? 217.585 221.186 201.475 1.00 10.51  ? 165 GLN A O     1 
ATOM   1130  C  CB    . GLN A 1 165 ? 217.804 219.437 203.653 1.00 12.59  ? 165 GLN A CB    1 
ATOM   1131  C  CG    . GLN A 1 165 ? 219.035 218.782 203.071 1.00 15.58  ? 165 GLN A CG    1 
ATOM   1132  C  CD    . GLN A 1 165 ? 219.099 217.297 203.352 1.00 15.46  ? 165 GLN A CD    1 
ATOM   1133  O  OE1   . GLN A 1 165 ? 218.093 216.584 203.332 1.00 14.38  ? 165 GLN A OE1   1 
ATOM   1134  N  NE2   . GLN A 1 165 ? 220.309 216.820 203.589 1.00 16.35  ? 165 GLN A NE2   1 
ATOM   1135  N  N     . ALA A 1 166 ? 216.606 222.754 202.754 1.00 9.33   ? 166 ALA A N     1 
ATOM   1136  C  CA    . ALA A 1 166 ? 215.958 223.408 201.627 1.00 9.14   ? 166 ALA A CA    1 
ATOM   1137  C  C     . ALA A 1 166 ? 216.976 223.817 200.563 1.00 8.47   ? 166 ALA A C     1 
ATOM   1138  O  O     . ALA A 1 166 ? 216.766 223.580 199.373 1.00 8.15   ? 166 ALA A O     1 
ATOM   1139  C  CB    . ALA A 1 166 ? 215.145 224.600 202.087 1.00 9.57   ? 166 ALA A CB    1 
ATOM   1140  N  N     . ALA A 1 167 ? 218.060 224.479 200.966 1.00 8.21   ? 167 ALA A N     1 
ATOM   1141  C  CA    . ALA A 1 167 ? 219.054 224.947 200.022 1.00 8.25   ? 167 ALA A CA    1 
ATOM   1142  C  C     . ALA A 1 167 ? 219.729 223.765 199.335 1.00 7.65   ? 167 ALA A C     1 
ATOM   1143  O  O     . ALA A 1 167 ? 219.928 223.782 198.132 1.00 7.62   ? 167 ALA A O     1 
ATOM   1144  C  CB    . ALA A 1 167 ? 220.075 225.825 200.720 1.00 8.40   ? 167 ALA A CB    1 
ATOM   1145  N  N     . TYR A 1 168 ? 220.100 222.747 200.105 1.00 7.86   ? 168 TYR A N     1 
ATOM   1146  C  CA    . TYR A 1 168 ? 220.767 221.586 199.551 1.00 8.33   ? 168 TYR A CA    1 
ATOM   1147  C  C     . TYR A 1 168 ? 219.836 220.852 198.590 1.00 7.85   ? 168 TYR A C     1 
ATOM   1148  O  O     . TYR A 1 168 ? 220.262 220.439 197.512 1.00 7.94   ? 168 TYR A O     1 
ATOM   1149  C  CB    . TYR A 1 168 ? 221.250 220.692 200.693 1.00 9.16   ? 168 TYR A CB    1 
ATOM   1150  C  CG    . TYR A 1 168 ? 222.177 219.574 200.249 1.00 10.71  ? 168 TYR A CG    1 
ATOM   1151  C  CD1   . TYR A 1 168 ? 223.450 219.871 199.793 1.00 11.35  ? 168 TYR A CD1   1 
ATOM   1152  C  CD2   . TYR A 1 168 ? 221.773 218.236 200.260 1.00 11.07  ? 168 TYR A CD2   1 
ATOM   1153  C  CE1   . TYR A 1 168 ? 224.318 218.878 199.378 1.00 12.25  ? 168 TYR A CE1   1 
ATOM   1154  C  CE2   . TYR A 1 168 ? 222.635 217.232 199.854 1.00 12.09  ? 168 TYR A CE2   1 
ATOM   1155  C  CZ    . TYR A 1 168 ? 223.907 217.553 199.416 1.00 12.67  ? 168 TYR A CZ    1 
ATOM   1156  O  OH    . TYR A 1 168 ? 224.749 216.560 199.014 1.00 14.55  ? 168 TYR A OH    1 
ATOM   1157  N  N     . SER A 1 169 ? 218.575 220.666 198.985 1.00 7.18   ? 169 SER A N     1 
ATOM   1158  C  CA    . SER A 1 169 ? 217.611 219.965 198.151 1.00 6.67   ? 169 SER A CA    1 
ATOM   1159  C  C     . SER A 1 169 ? 217.340 220.707 196.845 1.00 6.40   ? 169 SER A C     1 
ATOM   1160  O  O     . SER A 1 169 ? 217.206 220.082 195.793 1.00 6.14   ? 169 SER A O     1 
ATOM   1161  C  CB    . SER A 1 169 ? 216.322 219.723 198.907 1.00 6.69   ? 169 SER A CB    1 
ATOM   1162  O  OG    . SER A 1 169 ? 216.561 218.880 200.017 1.00 6.54   ? 169 SER A OG    1 
ATOM   1163  N  N     . ALA A 1 170 ? 217.243 222.038 196.915 1.00 6.17   ? 170 ALA A N     1 
ATOM   1164  C  CA    . ALA A 1 170 ? 217.034 222.844 195.725 1.00 6.33   ? 170 ALA A CA    1 
ATOM   1165  C  C     . ALA A 1 170 ? 218.189 222.648 194.742 1.00 6.65   ? 170 ALA A C     1 
ATOM   1166  O  O     . ALA A 1 170 ? 217.970 222.473 193.548 1.00 6.39   ? 170 ALA A O     1 
ATOM   1167  C  CB    . ALA A 1 170 ? 216.867 224.304 196.080 1.00 6.32   ? 170 ALA A CB    1 
ATOM   1168  N  N     . SER A 1 171 ? 219.427 222.703 195.250 1.00 6.93   ? 171 SER A N     1 
ATOM   1169  C  CA    . SER A 1 171 ? 220.593 222.565 194.391 1.00 7.07   ? 171 SER A CA    1 
ATOM   1170  C  C     . SER A 1 171 ? 220.638 221.171 193.772 1.00 7.26   ? 171 SER A C     1 
ATOM   1171  O  O     . SER A 1 171 ? 220.892 221.029 192.576 1.00 7.54   ? 171 SER A O     1 
ATOM   1172  C  CB    . SER A 1 171 ? 221.864 222.884 195.149 1.00 6.99   ? 171 SER A CB    1 
ATOM   1173  O  OG    . SER A 1 171 ? 222.166 221.859 196.073 1.00 6.95   ? 171 SER A OG    1 
ATOM   1174  N  N     . LYS A 1 172 ? 220.404 220.137 194.580 1.00 7.63   ? 172 LYS A N     1 
ATOM   1175  C  CA    . LYS A 1 172 ? 220.451 218.775 194.076 1.00 7.99   ? 172 LYS A CA    1 
ATOM   1176  C  C     . LYS A 1 172 ? 219.252 218.461 193.186 1.00 7.73   ? 172 LYS A C     1 
ATOM   1177  O  O     . LYS A 1 172 ? 219.387 217.712 192.227 1.00 7.96   ? 172 LYS A O     1 
ATOM   1178  C  CB    . LYS A 1 172 ? 220.534 217.783 195.240 1.00 8.40   ? 172 LYS A CB    1 
ATOM   1179  C  CG    . LYS A 1 172 ? 221.817 217.903 196.044 1.00 9.18   ? 172 LYS A CG    1 
ATOM   1180  C  CD    . LYS A 1 172 ? 223.052 218.086 195.172 1.00 9.98   ? 172 LYS A CD    1 
ATOM   1181  C  CE    . LYS A 1 172 ? 224.332 217.824 195.920 1.00 10.78  ? 172 LYS A CE    1 
ATOM   1182  N  NZ    . LYS A 1 172 ? 225.468 217.696 195.014 1.00 11.39  ? 172 LYS A NZ    1 
ATOM   1183  N  N     . GLY A 1 173 ? 218.082 219.018 193.501 1.00 7.27   ? 173 GLY A N     1 
ATOM   1184  C  CA    . GLY A 1 173 ? 216.941 218.883 192.614 1.00 7.14   ? 173 GLY A CA    1 
ATOM   1185  C  C     . GLY A 1 173 ? 217.200 219.532 191.257 1.00 7.00   ? 173 GLY A C     1 
ATOM   1186  O  O     . GLY A 1 173 ? 216.705 219.067 190.237 1.00 6.81   ? 173 GLY A O     1 
ATOM   1187  N  N     . GLY A 1 174 ? 217.953 220.635 191.241 1.00 6.95   ? 174 GLY A N     1 
ATOM   1188  C  CA    . GLY A 1 174 ? 218.332 221.258 189.985 1.00 6.99   ? 174 GLY A CA    1 
ATOM   1189  C  C     . GLY A 1 174 ? 219.224 220.353 189.133 1.00 6.97   ? 174 GLY A C     1 
ATOM   1190  O  O     . GLY A 1 174 ? 219.085 220.295 187.923 1.00 6.93   ? 174 GLY A O     1 
ATOM   1191  N  N     . ILE A 1 175 ? 220.159 219.640 189.776 1.00 7.40   ? 175 ILE A N     1 
ATOM   1192  C  CA    . ILE A 1 175 ? 221.004 218.704 189.053 1.00 7.93   ? 175 ILE A CA    1 
ATOM   1193  C  C     . ILE A 1 175 ? 220.160 217.574 188.463 1.00 8.24   ? 175 ILE A C     1 
ATOM   1194  O  O     . ILE A 1 175 ? 220.361 217.175 187.317 1.00 8.41   ? 175 ILE A O     1 
ATOM   1195  C  CB    . ILE A 1 175 ? 222.111 218.173 189.979 1.00 8.65   ? 175 ILE A CB    1 
ATOM   1196  C  CG1   . ILE A 1 175 ? 223.102 219.286 190.315 1.00 9.47   ? 175 ILE A CG1   1 
ATOM   1197  C  CG2   . ILE A 1 175 ? 222.815 216.966 189.360 1.00 8.63   ? 175 ILE A CG2   1 
ATOM   1198  C  CD1   . ILE A 1 175 ? 223.833 219.053 191.611 1.00 10.10  ? 175 ILE A CD1   1 
ATOM   1199  N  N     . VAL A 1 176 ? 219.212 217.054 189.234 1.00 8.63   ? 176 VAL A N     1 
ATOM   1200  C  CA    . VAL A 1 176 ? 218.316 216.019 188.731 1.00 9.32   ? 176 VAL A CA    1 
ATOM   1201  C  C     . VAL A 1 176 ? 217.509 216.564 187.548 1.00 9.95   ? 176 VAL A C     1 
ATOM   1202  O  O     . VAL A 1 176 ? 217.358 215.887 186.533 1.00 10.27  ? 176 VAL A O     1 
ATOM   1203  C  CB    . VAL A 1 176 ? 217.392 215.518 189.854 1.00 9.48   ? 176 VAL A CB    1 
ATOM   1204  C  CG1   . VAL A 1 176 ? 216.265 214.648 189.303 1.00 9.94   ? 176 VAL A CG1   1 
ATOM   1205  C  CG2   . VAL A 1 176 ? 218.178 214.784 190.918 1.00 9.17   ? 176 VAL A CG2   1 
ATOM   1206  N  N     . GLY A 1 177 ? 216.990 217.787 187.683 1.00 9.44   ? 177 GLY A N     1 
ATOM   1207  C  CA    . GLY A 1 177 ? 216.141 218.355 186.656 1.00 10.55  ? 177 GLY A CA    1 
ATOM   1208  C  C     . GLY A 1 177 ? 216.861 218.524 185.317 1.00 11.21  ? 177 GLY A C     1 
ATOM   1209  O  O     . GLY A 1 177 ? 216.283 218.269 184.270 1.00 11.48  ? 177 GLY A O     1 
ATOM   1210  N  N     . MET A 1 178 ? 218.128 218.949 185.353 1.00 11.33  ? 178 MET A N     1 
ATOM   1211  C  CA    . MET A 1 178 ? 218.834 219.270 184.125 1.00 12.32  ? 178 MET A CA    1 
ATOM   1212  C  C     . MET A 1 178 ? 219.568 218.063 183.542 1.00 12.34  ? 178 MET A C     1 
ATOM   1213  O  O     . MET A 1 178 ? 220.186 218.204 182.501 1.00 14.08  ? 178 MET A O     1 
ATOM   1214  C  CB    . MET A 1 178 ? 219.793 220.441 184.350 1.00 12.97  ? 178 MET A CB    1 
ATOM   1215  C  CG    . MET A 1 178 ? 221.113 220.076 184.997 1.00 13.85  ? 178 MET A CG    1 
ATOM   1216  S  SD    . MET A 1 178 ? 222.013 221.558 185.526 1.00 14.37  ? 178 MET A SD    1 
ATOM   1217  C  CE    . MET A 1 178 ? 223.403 220.751 186.328 1.00 14.71  ? 178 MET A CE    1 
ATOM   1218  N  N     . THR A 1 179 ? 219.512 216.901 184.189 1.00 11.17  ? 179 THR A N     1 
ATOM   1219  C  CA    . THR A 1 179 ? 220.235 215.737 183.706 1.00 12.27  ? 179 THR A CA    1 
ATOM   1220  C  C     . THR A 1 179 ? 219.729 215.323 182.318 1.00 12.77  ? 179 THR A C     1 
ATOM   1221  O  O     . THR A 1 179 ? 220.519 215.160 181.389 1.00 12.69  ? 179 THR A O     1 
ATOM   1222  C  CB    . THR A 1 179 ? 220.115 214.579 184.697 1.00 11.96  ? 179 THR A CB    1 
ATOM   1223  O  OG1   . THR A 1 179 ? 220.770 214.939 185.911 1.00 12.61  ? 179 THR A OG1   1 
ATOM   1224  C  CG2   . THR A 1 179 ? 220.752 213.324 184.143 1.00 12.73  ? 179 THR A CG2   1 
ATOM   1225  N  N     . LEU A 1 180 ? 218.410 215.137 182.173 1.00 13.45  ? 180 LEU A N     1 
ATOM   1226  C  CA    . LEU A 1 180 ? 217.849 214.708 180.898 1.00 13.60  ? 180 LEU A CA    1 
ATOM   1227  C  C     . LEU A 1 180 ? 218.030 215.776 179.812 1.00 14.46  ? 180 LEU A C     1 
ATOM   1228  O  O     . LEU A 1 180 ? 218.452 215.444 178.705 1.00 14.49  ? 180 LEU A O     1 
ATOM   1229  C  CB    . LEU A 1 180 ? 216.384 214.314 181.036 1.00 14.87  ? 180 LEU A CB    1 
ATOM   1230  C  CG    . LEU A 1 180 ? 215.712 213.830 179.743 1.00 15.51  ? 180 LEU A CG    1 
ATOM   1231  C  CD1   . LEU A 1 180 ? 216.383 212.594 179.219 1.00 15.56  ? 180 LEU A CD1   1 
ATOM   1232  C  CD2   . LEU A 1 180 ? 214.238 213.539 179.960 1.00 17.80  ? 180 LEU A CD2   1 
ATOM   1233  N  N     . PRO A 1 181 ? 217.701 217.069 180.029 1.00 13.87  ? 181 PRO A N     1 
ATOM   1234  C  CA    . PRO A 1 181 ? 217.908 218.063 178.977 1.00 14.44  ? 181 PRO A CA    1 
ATOM   1235  C  C     . PRO A 1 181 ? 219.345 218.166 178.490 1.00 14.12  ? 181 PRO A C     1 
ATOM   1236  O  O     . PRO A 1 181 ? 219.596 218.334 177.298 1.00 15.78  ? 181 PRO A O     1 
ATOM   1237  C  CB    . PRO A 1 181 ? 217.460 219.402 179.575 1.00 14.50  ? 181 PRO A CB    1 
ATOM   1238  C  CG    . PRO A 1 181 ? 216.692 219.021 180.812 1.00 14.82  ? 181 PRO A CG    1 
ATOM   1239  C  CD    . PRO A 1 181 ? 217.066 217.637 181.235 1.00 14.74  ? 181 PRO A CD    1 
ATOM   1240  N  N     . ILE A 1 182 ? 220.311 218.074 179.408 1.00 13.31  ? 182 ILE A N     1 
ATOM   1241  C  CA    . ILE A 1 182 ? 221.704 218.148 179.004 1.00 12.02  ? 182 ILE A CA    1 
ATOM   1242  C  C     . ILE A 1 182 ? 222.074 216.890 178.220 1.00 11.32  ? 182 ILE A C     1 
ATOM   1243  O  O     . ILE A 1 182 ? 222.805 216.964 177.238 1.00 11.45  ? 182 ILE A O     1 
ATOM   1244  C  CB    . ILE A 1 182 ? 222.614 218.388 180.220 1.00 11.96  ? 182 ILE A CB    1 
ATOM   1245  C  CG1   . ILE A 1 182 ? 222.339 219.751 180.838 1.00 12.04  ? 182 ILE A CG1   1 
ATOM   1246  C  CG2   . ILE A 1 182 ? 224.079 218.259 179.827 1.00 12.06  ? 182 ILE A CG2   1 
ATOM   1247  C  CD1   . ILE A 1 182 ? 223.207 220.072 182.040 1.00 12.37  ? 182 ILE A CD1   1 
ATOM   1248  N  N     . ALA A 1 183 ? 221.587 215.730 178.659 1.00 10.90  ? 183 ALA A N     1 
ATOM   1249  C  CA    . ALA A 1 183 ? 221.783 214.494 177.906 1.00 11.20  ? 183 ALA A CA    1 
ATOM   1250  C  C     . ALA A 1 183 ? 221.198 214.633 176.499 1.00 11.97  ? 183 ALA A C     1 
ATOM   1251  O  O     . ALA A 1 183 ? 221.810 214.195 175.529 1.00 11.65  ? 183 ALA A O     1 
ATOM   1252  C  CB    . ALA A 1 183 ? 221.179 213.315 178.630 1.00 10.60  ? 183 ALA A CB    1 
ATOM   1253  N  N     . ARG A 1 184 ? 220.012 215.234 176.394 1.00 12.46  ? 184 ARG A N     1 
ATOM   1254  C  CA    . ARG A 1 184 ? 219.422 215.509 175.096 1.00 13.65  ? 184 ARG A CA    1 
ATOM   1255  C  C     . ARG A 1 184 ? 220.244 216.541 174.324 1.00 14.52  ? 184 ARG A C     1 
ATOM   1256  O  O     . ARG A 1 184 ? 220.402 216.408 173.116 1.00 16.57  ? 184 ARG A O     1 
ATOM   1257  C  CB    . ARG A 1 184 ? 217.981 215.998 175.270 1.00 14.27  ? 184 ARG A CB    1 
ATOM   1258  C  CG    . ARG A 1 184 ? 217.041 214.918 175.772 1.00 14.05  ? 184 ARG A CG    1 
ATOM   1259  C  CD    . ARG A 1 184 ? 215.717 215.543 176.191 1.00 14.87  ? 184 ARG A CD    1 
ATOM   1260  N  NE    . ARG A 1 184 ? 214.656 214.533 176.211 1.00 15.32  ? 184 ARG A NE    1 
ATOM   1261  C  CZ    . ARG A 1 184 ? 213.379 214.773 176.474 1.00 15.57  ? 184 ARG A CZ    1 
ATOM   1262  N  NH1   . ARG A 1 184 ? 212.978 215.980 176.839 1.00 15.36  ? 184 ARG A NH1   1 
ATOM   1263  N  NH2   . ARG A 1 184 ? 212.515 213.775 176.373 1.00 15.46  ? 184 ARG A NH2   1 
ATOM   1264  N  N     . ASP A 1 185 ? 220.767 217.554 175.011 1.00 15.91  ? 185 ASP A N     1 
ATOM   1265  C  CA    . ASP A 1 185 ? 221.613 218.548 174.367 1.00 17.61  ? 185 ASP A CA    1 
ATOM   1266  C  C     . ASP A 1 185 ? 222.847 217.895 173.744 1.00 16.60  ? 185 ASP A C     1 
ATOM   1267  O  O     . ASP A 1 185 ? 223.200 218.200 172.609 1.00 17.29  ? 185 ASP A O     1 
ATOM   1268  C  CB    . ASP A 1 185 ? 222.079 219.600 175.361 1.00 20.44  ? 185 ASP A CB    1 
ATOM   1269  C  CG    . ASP A 1 185 ? 221.067 220.690 175.643 1.00 24.69  ? 185 ASP A CG    1 
ATOM   1270  O  OD1   . ASP A 1 185 ? 221.351 221.546 176.519 1.00 25.98  ? 185 ASP A OD1   1 
ATOM   1271  O  OD2   . ASP A 1 185 ? 219.982 220.617 175.022 1.00 28.18  ? 185 ASP A OD2   1 
ATOM   1272  N  N     . LEU A 1 186 ? 223.512 217.000 174.494 1.00 15.26  ? 186 LEU A N     1 
ATOM   1273  C  CA    . LEU A 1 186 ? 224.801 216.462 174.097 1.00 14.34  ? 186 LEU A CA    1 
ATOM   1274  C  C     . LEU A 1 186 ? 224.680 215.125 173.377 1.00 14.16  ? 186 LEU A C     1 
ATOM   1275  O  O     . LEU A 1 186 ? 225.700 214.545 173.019 1.00 14.68  ? 186 LEU A O     1 
ATOM   1276  C  CB    . LEU A 1 186 ? 225.684 216.318 175.332 1.00 14.64  ? 186 LEU A CB    1 
ATOM   1277  C  CG    . LEU A 1 186 ? 225.864 217.587 176.166 1.00 14.24  ? 186 LEU A CG    1 
ATOM   1278  C  CD1   . LEU A 1 186 ? 226.838 217.332 177.298 1.00 14.05  ? 186 LEU A CD1   1 
ATOM   1279  C  CD2   . LEU A 1 186 ? 226.317 218.760 175.302 1.00 14.92  ? 186 LEU A CD2   1 
ATOM   1280  N  N     . ALA A 1 187 ? 223.453 214.630 173.162 1.00 14.05  ? 187 ALA A N     1 
ATOM   1281  C  CA    . ALA A 1 187 ? 223.264 213.361 172.471 1.00 15.90  ? 187 ALA A CA    1 
ATOM   1282  C  C     . ALA A 1 187 ? 223.856 213.387 171.061 1.00 17.25  ? 187 ALA A C     1 
ATOM   1283  O  O     . ALA A 1 187 ? 224.515 212.423 170.678 1.00 17.58  ? 187 ALA A O     1 
ATOM   1284  C  CB    . ALA A 1 187 ? 221.807 212.975 172.455 1.00 16.22  ? 187 ALA A CB    1 
ATOM   1285  N  N     . PRO A 1 188 ? 223.637 214.424 170.218 1.00 20.97  ? 188 PRO A N     1 
ATOM   1286  C  CA    . PRO A 1 188 ? 224.197 214.415 168.866 1.00 22.62  ? 188 PRO A CA    1 
ATOM   1287  C  C     . PRO A 1 188 ? 225.711 214.296 168.817 1.00 23.18  ? 188 PRO A C     1 
ATOM   1288  O  O     . PRO A 1 188 ? 226.241 213.768 167.841 1.00 26.48  ? 188 PRO A O     1 
ATOM   1289  C  CB    . PRO A 1 188 ? 223.725 215.754 168.277 1.00 22.74  ? 188 PRO A CB    1 
ATOM   1290  C  CG    . PRO A 1 188 ? 222.457 216.041 169.033 1.00 22.85  ? 188 PRO A CG    1 
ATOM   1291  C  CD    . PRO A 1 188 ? 222.790 215.606 170.433 1.00 21.21  ? 188 PRO A CD    1 
ATOM   1292  N  N     . ILE A 1 189 ? 226.404 214.787 169.855 1.00 22.25  ? 189 ILE A N     1 
ATOM   1293  C  CA    . ILE A 1 189 ? 227.854 214.739 169.851 1.00 21.79  ? 189 ILE A CA    1 
ATOM   1294  C  C     . ILE A 1 189 ? 228.376 213.599 170.719 1.00 19.02  ? 189 ILE A C     1 
ATOM   1295  O  O     . ILE A 1 189 ? 229.556 213.536 171.013 1.00 19.52  ? 189 ILE A O     1 
ATOM   1296  C  CB    . ILE A 1 189 ? 228.451 216.089 170.272 1.00 26.18  ? 189 ILE A CB    1 
ATOM   1297  C  CG1   . ILE A 1 189 ? 228.024 216.491 171.637 1.00 26.34  ? 189 ILE A CG1   1 
ATOM   1298  C  CG2   . ILE A 1 189 ? 228.039 217.154 169.262 1.00 29.27  ? 189 ILE A CG2   1 
ATOM   1299  C  CD1   . ILE A 1 189 ? 228.720 217.751 172.109 1.00 27.64  ? 189 ILE A CD1   1 
ATOM   1300  N  N     . GLY A 1 190 ? 227.490 212.735 171.220 1.00 15.80  ? 190 GLY A N     1 
ATOM   1301  C  CA    . GLY A 1 190 ? 227.903 211.478 171.831 1.00 14.50  ? 190 GLY A CA    1 
ATOM   1302  C  C     . GLY A 1 190 ? 228.503 211.644 173.226 1.00 12.71  ? 190 GLY A C     1 
ATOM   1303  O  O     . GLY A 1 190 ? 229.459 210.958 173.559 1.00 13.06  ? 190 GLY A O     1 
ATOM   1304  N  N     . ILE A 1 191 ? 227.929 212.545 174.032 1.00 11.67  ? 191 ILE A N     1 
ATOM   1305  C  CA    . ILE A 1 191 ? 228.316 212.678 175.426 1.00 10.88  ? 191 ILE A CA    1 
ATOM   1306  C  C     . ILE A 1 191 ? 227.153 212.220 176.294 1.00 9.68   ? 191 ILE A C     1 
ATOM   1307  O  O     . ILE A 1 191 ? 226.103 212.844 176.288 1.00 9.92   ? 191 ILE A O     1 
ATOM   1308  C  CB    . ILE A 1 191 ? 228.739 214.119 175.755 1.00 11.13  ? 191 ILE A CB    1 
ATOM   1309  C  CG1   . ILE A 1 191 ? 229.948 214.536 174.931 1.00 11.42  ? 191 ILE A CG1   1 
ATOM   1310  C  CG2   . ILE A 1 191 ? 229.012 214.277 177.246 1.00 10.89  ? 191 ILE A CG2   1 
ATOM   1311  C  CD1   . ILE A 1 191 ? 230.251 216.019 175.030 1.00 11.63  ? 191 ILE A CD1   1 
ATOM   1312  N  N     . ARG A 1 192 ? 227.364 211.149 177.052 1.00 9.18   ? 192 ARG A N     1 
ATOM   1313  C  CA    . ARG A 1 192 ? 226.357 210.672 177.985 1.00 8.86   ? 192 ARG A CA    1 
ATOM   1314  C  C     . ARG A 1 192 ? 226.405 211.500 179.268 1.00 8.53   ? 192 ARG A C     1 
ATOM   1315  O  O     . ARG A 1 192 ? 227.475 211.830 179.769 1.00 9.21   ? 192 ARG A O     1 
ATOM   1316  C  CB    . ARG A 1 192 ? 226.567 209.194 178.309 1.00 8.85   ? 192 ARG A CB    1 
ATOM   1317  C  CG    . ARG A 1 192 ? 226.317 208.287 177.116 1.00 9.08   ? 192 ARG A CG    1 
ATOM   1318  C  CD    . ARG A 1 192 ? 226.274 206.840 177.518 1.00 8.91   ? 192 ARG A CD    1 
ATOM   1319  N  NE    . ARG A 1 192 ? 227.596 206.326 177.891 1.00 8.56   ? 192 ARG A NE    1 
ATOM   1320  C  CZ    . ARG A 1 192 ? 227.938 205.864 179.084 1.00 8.34   ? 192 ARG A CZ    1 
ATOM   1321  N  NH1   . ARG A 1 192 ? 227.080 205.871 180.095 1.00 8.30   ? 192 ARG A NH1   1 
ATOM   1322  N  NH2   . ARG A 1 192 ? 229.153 205.401 179.279 1.00 8.31   ? 192 ARG A NH2   1 
ATOM   1323  N  N     . VAL A 1 193 ? 225.225 211.805 179.801 1.00 8.47   ? 193 VAL A N     1 
ATOM   1324  C  CA    . VAL A 1 193 ? 225.097 212.571 181.025 1.00 8.23   ? 193 VAL A CA    1 
ATOM   1325  C  C     . VAL A 1 193 ? 224.287 211.743 182.009 1.00 8.07   ? 193 VAL A C     1 
ATOM   1326  O  O     . VAL A 1 193 ? 223.146 211.385 181.737 1.00 7.97   ? 193 VAL A O     1 
ATOM   1327  C  CB    . VAL A 1 193 ? 224.449 213.946 180.803 1.00 8.39   ? 193 VAL A CB    1 
ATOM   1328  C  CG1   . VAL A 1 193 ? 224.463 214.766 182.084 1.00 8.51   ? 193 VAL A CG1   1 
ATOM   1329  C  CG2   . VAL A 1 193 ? 225.152 214.710 179.687 1.00 8.40   ? 193 VAL A CG2   1 
ATOM   1330  N  N     . MET A 1 194 ? 224.898 211.432 183.149 1.00 7.84   ? 194 MET A N     1 
ATOM   1331  C  CA    . MET A 1 194 ? 224.293 210.573 184.146 1.00 7.94   ? 194 MET A CA    1 
ATOM   1332  C  C     . MET A 1 194 ? 224.446 211.237 185.507 1.00 7.66   ? 194 MET A C     1 
ATOM   1333  O  O     . MET A 1 194 ? 225.330 212.061 185.717 1.00 8.22   ? 194 MET A O     1 
ATOM   1334  C  CB    . MET A 1 194 ? 224.958 209.191 184.188 1.00 8.57   ? 194 MET A CB    1 
ATOM   1335  C  CG    . MET A 1 194 ? 224.467 208.219 183.149 1.00 9.22   ? 194 MET A CG    1 
ATOM   1336  S  SD    . MET A 1 194 ? 222.722 207.806 183.340 1.00 9.76   ? 194 MET A SD    1 
ATOM   1337  C  CE    . MET A 1 194 ? 222.753 206.849 184.863 1.00 9.73   ? 194 MET A CE    1 
ATOM   1338  N  N     . THR A 1 195 ? 223.543 210.890 186.416 1.00 7.53   ? 195 THR A N     1 
ATOM   1339  C  CA    . THR A 1 195 ? 223.547 211.458 187.750 1.00 7.69   ? 195 THR A CA    1 
ATOM   1340  C  C     . THR A 1 195 ? 223.442 210.324 188.759 1.00 7.35   ? 195 THR A C     1 
ATOM   1341  O  O     . THR A 1 195 ? 222.604 209.437 188.612 1.00 8.09   ? 195 THR A O     1 
ATOM   1342  C  CB    . THR A 1 195 ? 222.409 212.471 187.895 1.00 7.91   ? 195 THR A CB    1 
ATOM   1343  O  OG1   . THR A 1 195 ? 222.658 213.582 187.037 1.00 7.92   ? 195 THR A OG1   1 
ATOM   1344  C  CG2   . THR A 1 195 ? 222.319 212.991 189.312 1.00 8.17   ? 195 THR A CG2   1 
ATOM   1345  N  N     . ILE A 1 196 ? 224.255 210.411 189.808 1.00 7.28   ? 196 ILE A N     1 
ATOM   1346  C  CA    . ILE A 1 196 ? 224.151 209.533 190.956 1.00 7.24   ? 196 ILE A CA    1 
ATOM   1347  C  C     . ILE A 1 196 ? 223.581 210.335 192.114 1.00 7.63   ? 196 ILE A C     1 
ATOM   1348  O  O     . ILE A 1 196 ? 224.016 211.463 192.373 1.00 8.32   ? 196 ILE A O     1 
ATOM   1349  C  CB    . ILE A 1 196 ? 225.515 208.932 191.324 1.00 7.47   ? 196 ILE A CB    1 
ATOM   1350  C  CG1   . ILE A 1 196 ? 226.086 208.133 190.162 1.00 7.64   ? 196 ILE A CG1   1 
ATOM   1351  C  CG2   . ILE A 1 196 ? 225.422 208.083 192.594 1.00 7.32   ? 196 ILE A CG2   1 
ATOM   1352  C  CD1   . ILE A 1 196 ? 227.510 207.657 190.396 1.00 7.99   ? 196 ILE A CD1   1 
ATOM   1353  N  N     . ALA A 1 197 ? 222.590 209.764 192.790 1.00 7.60   ? 197 ALA A N     1 
ATOM   1354  C  CA    . ALA A 1 197 ? 221.998 210.389 193.961 1.00 7.92   ? 197 ALA A CA    1 
ATOM   1355  C  C     . ALA A 1 197 ? 222.390 209.577 195.182 1.00 8.51   ? 197 ALA A C     1 
ATOM   1356  O  O     . ALA A 1 197 ? 221.670 208.675 195.603 1.00 9.45   ? 197 ALA A O     1 
ATOM   1357  C  CB    . ALA A 1 197 ? 220.498 210.486 193.816 1.00 7.77   ? 197 ALA A CB    1 
ATOM   1358  N  N     . PRO A 1 198 ? 223.556 209.850 195.797 1.00 9.45   ? 198 PRO A N     1 
ATOM   1359  C  CA    . PRO A 1 198 ? 223.983 209.056 196.941 1.00 9.82   ? 198 PRO A CA    1 
ATOM   1360  C  C     . PRO A 1 198 ? 223.107 209.329 198.147 1.00 10.58  ? 198 PRO A C     1 
ATOM   1361  O  O     . PRO A 1 198 ? 222.552 210.412 198.290 1.00 10.88  ? 198 PRO A O     1 
ATOM   1362  C  CB    . PRO A 1 198 ? 225.431 209.486 197.183 1.00 9.94   ? 198 PRO A CB    1 
ATOM   1363  C  CG    . PRO A 1 198 ? 225.543 210.806 196.501 1.00 10.11  ? 198 PRO A CG    1 
ATOM   1364  C  CD    . PRO A 1 198 ? 224.556 210.845 195.377 1.00 9.67   ? 198 PRO A CD    1 
ATOM   1365  N  N     . GLY A 1 199 ? 222.979 208.318 198.999 1.00 11.69  ? 199 GLY A N     1 
ATOM   1366  C  CA    . GLY A 1 199 ? 222.275 208.480 200.249 1.00 12.75  ? 199 GLY A CA    1 
ATOM   1367  C  C     . GLY A 1 199 ? 223.225 209.002 201.321 1.00 13.97  ? 199 GLY A C     1 
ATOM   1368  O  O     . GLY A 1 199 ? 223.887 210.018 201.137 1.00 15.72  ? 199 GLY A O     1 
ATOM   1369  N  N     . LEU A 1 200 ? 223.287 208.286 202.439 1.00 15.40  ? 200 LEU A N     1 
ATOM   1370  C  CA    . LEU A 1 200 ? 224.127 208.679 203.557 1.00 17.09  ? 200 LEU A CA    1 
ATOM   1371  C  C     . LEU A 1 200 ? 225.470 207.987 203.388 1.00 16.41  ? 200 LEU A C     1 
ATOM   1372  O  O     . LEU A 1 200 ? 225.546 206.770 203.470 1.00 18.07  ? 200 LEU A O     1 
ATOM   1373  C  CB    . LEU A 1 200 ? 223.441 208.290 204.863 1.00 19.23  ? 200 LEU A CB    1 
ATOM   1374  C  CG    . LEU A 1 200 ? 222.002 208.796 205.016 1.00 22.67  ? 200 LEU A CG    1 
ATOM   1375  C  CD1   . LEU A 1 200 ? 221.391 208.354 206.322 1.00 23.33  ? 200 LEU A CD1   1 
ATOM   1376  C  CD2   . LEU A 1 200 ? 221.920 210.316 204.877 1.00 24.29  ? 200 LEU A CD2   1 
ATOM   1377  N  N     . PHE A 1 201 ? 226.524 208.763 203.142 1.00 15.76  ? 201 PHE A N     1 
ATOM   1378  C  CA    . PHE A 1 201 ? 227.856 208.224 202.909 1.00 17.25  ? 201 PHE A CA    1 
ATOM   1379  C  C     . PHE A 1 201 ? 228.812 208.755 203.975 1.00 19.79  ? 201 PHE A C     1 
ATOM   1380  O  O     . PHE A 1 201 ? 228.607 209.835 204.536 1.00 20.73  ? 201 PHE A O     1 
ATOM   1381  C  CB    . PHE A 1 201 ? 228.375 208.613 201.522 1.00 16.16  ? 201 PHE A CB    1 
ATOM   1382  C  CG    . PHE A 1 201 ? 227.995 207.604 200.459 1.00 15.24  ? 201 PHE A CG    1 
ATOM   1383  C  CD1   . PHE A 1 201 ? 226.673 207.479 200.042 1.00 14.79  ? 201 PHE A CD1   1 
ATOM   1384  C  CD2   . PHE A 1 201 ? 228.949 206.775 199.892 1.00 14.51  ? 201 PHE A CD2   1 
ATOM   1385  C  CE1   . PHE A 1 201 ? 226.316 206.529 199.094 1.00 14.44  ? 201 PHE A CE1   1 
ATOM   1386  C  CE2   . PHE A 1 201 ? 228.593 205.840 198.926 1.00 14.76  ? 201 PHE A CE2   1 
ATOM   1387  C  CZ    . PHE A 1 201 ? 227.276 205.713 198.536 1.00 14.47  ? 201 PHE A CZ    1 
ATOM   1388  N  N     . GLY A 1 202 ? 229.858 207.972 204.245 1.00 23.04  ? 202 GLY A N     1 
ATOM   1389  C  CA    . GLY A 1 202 ? 230.883 208.355 205.199 1.00 26.75  ? 202 GLY A CA    1 
ATOM   1390  C  C     . GLY A 1 202 ? 231.793 209.448 204.641 1.00 31.98  ? 202 GLY A C     1 
ATOM   1391  O  O     . GLY A 1 202 ? 232.982 209.230 204.395 1.00 34.76  ? 202 GLY A O     1 
ATOM   1392  N  N     . THR A 1 203 ? 231.202 210.637 204.452 1.00 36.36  ? 203 THR A N     1 
ATOM   1393  C  CA    . THR A 1 203 ? 231.922 211.792 203.928 1.00 43.59  ? 203 THR A CA    1 
ATOM   1394  C  C     . THR A 1 203 ? 231.917 212.901 204.973 1.00 50.27  ? 203 THR A C     1 
ATOM   1395  O  O     . THR A 1 203 ? 231.092 212.900 205.882 1.00 50.43  ? 203 THR A O     1 
ATOM   1396  C  CB    . THR A 1 203 ? 231.289 212.274 202.619 1.00 44.30  ? 203 THR A CB    1 
ATOM   1397  O  OG1   . THR A 1 203 ? 229.935 212.658 202.871 1.00 45.49  ? 203 THR A OG1   1 
ATOM   1398  C  CG2   . THR A 1 203 ? 231.370 211.191 201.558 1.00 44.44  ? 203 THR A CG2   1 
ATOM   1399  N  N     . PRO A 1 204 ? 232.836 213.884 204.884 1.00 61.95  ? 204 PRO A N     1 
ATOM   1400  C  CA    . PRO A 1 204 ? 232.807 215.012 205.816 1.00 65.79  ? 204 PRO A CA    1 
ATOM   1401  C  C     . PRO A 1 204 ? 231.492 215.777 205.854 1.00 69.37  ? 204 PRO A C     1 
ATOM   1402  O  O     . PRO A 1 204 ? 231.166 216.371 206.871 1.00 71.30  ? 204 PRO A O     1 
ATOM   1403  C  CB    . PRO A 1 204 ? 233.951 215.905 205.305 1.00 67.16  ? 204 PRO A CB    1 
ATOM   1404  C  CG    . PRO A 1 204 ? 234.882 214.948 204.607 1.00 68.54  ? 204 PRO A CG    1 
ATOM   1405  C  CD    . PRO A 1 204 ? 233.966 213.941 203.935 1.00 65.47  ? 204 PRO A CD    1 
ATOM   1406  N  N     . LEU A 1 205 ? 230.725 215.746 204.760 1.00 74.55  ? 205 LEU A N     1 
ATOM   1407  C  CA    . LEU A 1 205 ? 229.427 216.398 204.723 1.00 80.74  ? 205 LEU A CA    1 
ATOM   1408  C  C     . LEU A 1 205 ? 228.482 215.791 205.758 1.00 78.64  ? 205 LEU A C     1 
ATOM   1409  O  O     . LEU A 1 205 ? 227.611 216.483 206.272 1.00 81.08  ? 205 LEU A O     1 
ATOM   1410  C  CB    . LEU A 1 205 ? 228.835 216.316 203.319 1.00 86.35  ? 205 LEU A CB    1 
ATOM   1411  C  CG    . LEU A 1 205 ? 227.616 217.208 203.073 1.00 91.73  ? 205 LEU A CG    1 
ATOM   1412  C  CD1   . LEU A 1 205 ? 227.970 218.660 203.342 1.00 92.52  ? 205 LEU A CD1   1 
ATOM   1413  C  CD2   . LEU A 1 205 ? 227.103 217.036 201.658 1.00 94.28  ? 205 LEU A CD2   1 
ATOM   1414  N  N     . LEU A 1 206 ? 228.646 214.498 206.064 1.00 75.81  ? 206 LEU A N     1 
ATOM   1415  C  CA    . LEU A 1 206 ? 227.829 213.838 207.068 1.00 71.56  ? 206 LEU A CA    1 
ATOM   1416  C  C     . LEU A 1 206 ? 228.552 213.708 208.408 1.00 70.03  ? 206 LEU A C     1 
ATOM   1417  O  O     . LEU A 1 206 ? 227.903 213.671 209.449 1.00 64.76  ? 206 LEU A O     1 
ATOM   1418  C  CB    . LEU A 1 206 ? 227.407 212.462 206.541 1.00 72.09  ? 206 LEU A CB    1 
ATOM   1419  C  CG    . LEU A 1 206 ? 226.274 211.764 207.296 1.00 70.50  ? 206 LEU A CG    1 
ATOM   1420  C  CD1   . LEU A 1 206 ? 225.382 211.026 206.333 1.00 69.59  ? 206 LEU A CD1   1 
ATOM   1421  C  CD2   . LEU A 1 206 ? 226.798 210.794 208.326 1.00 73.84  ? 206 LEU A CD2   1 
ATOM   1422  N  N     . THR A 1 207 ? 229.891 213.620 208.393 1.00 71.29  ? 207 THR A N     1 
ATOM   1423  C  CA    . THR A 1 207 ? 230.668 213.491 209.621 1.00 74.27  ? 207 THR A CA    1 
ATOM   1424  C  C     . THR A 1 207 ? 230.523 214.734 210.506 1.00 69.60  ? 207 THR A C     1 
ATOM   1425  O  O     . THR A 1 207 ? 230.586 214.620 211.733 1.00 72.28  ? 207 THR A O     1 
ATOM   1426  C  CB    . THR A 1 207 ? 232.143 213.268 209.278 1.00 77.51  ? 207 THR A CB    1 
ATOM   1427  O  OG1   . THR A 1 207 ? 232.264 212.027 208.590 1.00 77.40  ? 207 THR A OG1   1 
ATOM   1428  C  CG2   . THR A 1 207 ? 233.048 213.269 210.496 1.00 80.67  ? 207 THR A CG2   1 
ATOM   1429  N  N     . SER A 1 208 ? 230.251 215.898 209.895 1.00 64.48  ? 208 SER A N     1 
ATOM   1430  C  CA    . SER A 1 208 ? 230.109 217.130 210.655 1.00 60.12  ? 208 SER A CA    1 
ATOM   1431  C  C     . SER A 1 208 ? 228.895 217.091 211.587 1.00 56.10  ? 208 SER A C     1 
ATOM   1432  O  O     . SER A 1 208 ? 228.839 217.865 212.542 1.00 57.76  ? 208 SER A O     1 
ATOM   1433  C  CB    . SER A 1 208 ? 230.034 218.320 209.746 1.00 62.54  ? 208 SER A CB    1 
ATOM   1434  O  OG    . SER A 1 208 ? 228.747 218.427 209.154 1.00 63.38  ? 208 SER A OG    1 
ATOM   1435  N  N     . LEU A 1 209 ? 227.934 216.198 211.310 1.00 46.03  ? 209 LEU A N     1 
ATOM   1436  C  CA    . LEU A 1 209 ? 226.778 216.035 212.175 1.00 40.02  ? 209 LEU A CA    1 
ATOM   1437  C  C     . LEU A 1 209 ? 227.227 215.453 213.512 1.00 37.01  ? 209 LEU A C     1 
ATOM   1438  O  O     . LEU A 1 209 ? 228.289 214.835 213.612 1.00 37.99  ? 209 LEU A O     1 
ATOM   1439  C  CB    . LEU A 1 209 ? 225.738 215.125 211.528 1.00 39.26  ? 209 LEU A CB    1 
ATOM   1440  C  CG    . LEU A 1 209 ? 224.961 215.689 210.340 1.00 39.62  ? 209 LEU A CG    1 
ATOM   1441  C  CD1   . LEU A 1 209 ? 224.051 214.622 209.765 1.00 39.85  ? 209 LEU A CD1   1 
ATOM   1442  C  CD2   . LEU A 1 209 ? 224.183 216.910 210.754 1.00 40.24  ? 209 LEU A CD2   1 
ATOM   1443  N  N     . PRO A 1 210 ? 226.435 215.624 214.594 1.00 32.74  ? 210 PRO A N     1 
ATOM   1444  C  CA    . PRO A 1 210 ? 226.722 214.932 215.850 1.00 31.94  ? 210 PRO A CA    1 
ATOM   1445  C  C     . PRO A 1 210 ? 226.818 213.425 215.639 1.00 31.57  ? 210 PRO A C     1 
ATOM   1446  O  O     . PRO A 1 210 ? 226.074 212.849 214.849 1.00 31.53  ? 210 PRO A O     1 
ATOM   1447  C  CB    . PRO A 1 210 ? 225.551 215.309 216.754 1.00 32.07  ? 210 PRO A CB    1 
ATOM   1448  C  CG    . PRO A 1 210 ? 225.031 216.604 216.163 1.00 33.50  ? 210 PRO A CG    1 
ATOM   1449  C  CD    . PRO A 1 210 ? 225.245 216.486 214.666 1.00 33.04  ? 210 PRO A CD    1 
ATOM   1450  N  N     . GLU A 1 211 ? 227.733 212.789 216.369 1.00 30.47  ? 211 GLU A N     1 
ATOM   1451  C  CA    . GLU A 1 211 ? 228.030 211.378 216.165 1.00 32.89  ? 211 GLU A CA    1 
ATOM   1452  C  C     . GLU A 1 211 ? 226.786 210.520 216.409 1.00 29.41  ? 211 GLU A C     1 
ATOM   1453  O  O     . GLU A 1 211 ? 226.537 209.559 215.693 1.00 28.85  ? 211 GLU A O     1 
ATOM   1454  C  CB    . GLU A 1 211 ? 229.174 210.952 217.081 1.00 39.14  ? 211 GLU A CB    1 
ATOM   1455  C  CG    . GLU A 1 211 ? 229.603 209.501 216.904 1.00 46.87  ? 211 GLU A CG    1 
ATOM   1456  C  CD    . GLU A 1 211 ? 230.788 209.094 217.768 1.00 57.76  ? 211 GLU A CD    1 
ATOM   1457  O  OE1   . GLU A 1 211 ? 231.473 209.958 218.374 1.00 60.58  ? 211 GLU A OE1   1 
ATOM   1458  O  OE2   . GLU A 1 211 ? 231.021 207.868 217.845 1.00 59.39  ? 211 GLU A OE2   1 
ATOM   1459  N  N     . LYS A 1 212 ? 226.012 210.886 217.431 1.00 26.06  ? 212 LYS A N     1 
ATOM   1460  C  CA    . LYS A 1 212 ? 224.802 210.154 217.767 1.00 24.36  ? 212 LYS A CA    1 
ATOM   1461  C  C     . LYS A 1 212 ? 223.773 210.262 216.644 1.00 20.67  ? 212 LYS A C     1 
ATOM   1462  O  O     . LYS A 1 212 ? 223.059 209.313 216.390 1.00 21.19  ? 212 LYS A O     1 
ATOM   1463  C  CB    . LYS A 1 212 ? 224.270 210.655 219.111 1.00 24.62  ? 212 LYS A CB    1 
ATOM   1464  C  CG    . LYS A 1 212 ? 224.997 209.966 220.259 1.00 25.83  ? 212 LYS A CG    1 
ATOM   1465  C  CD    . LYS A 1 212 ? 224.715 210.608 221.605 1.00 27.10  ? 212 LYS A CD    1 
ATOM   1466  C  CE    . LYS A 1 212 ? 224.861 209.670 222.759 1.00 27.59  ? 212 LYS A CE    1 
ATOM   1467  N  NZ    . LYS A 1 212 ? 224.336 210.301 223.977 1.00 28.55  ? 212 LYS A NZ    1 
ATOM   1468  N  N     . VAL A 1 213 ? 223.667 211.425 216.011 1.00 19.92  ? 213 VAL A N     1 
ATOM   1469  C  CA    . VAL A 1 213 ? 222.783 211.599 214.871 1.00 20.56  ? 213 VAL A CA    1 
ATOM   1470  C  C     . VAL A 1 213 ? 223.251 210.742 213.694 1.00 20.97  ? 213 VAL A C     1 
ATOM   1471  O  O     . VAL A 1 213 ? 222.442 210.082 213.043 1.00 21.57  ? 213 VAL A O     1 
ATOM   1472  C  CB    . VAL A 1 213 ? 222.682 213.081 214.482 1.00 21.10  ? 213 VAL A CB    1 
ATOM   1473  C  CG1   . VAL A 1 213 ? 221.978 213.265 213.140 1.00 20.52  ? 213 VAL A CG1   1 
ATOM   1474  C  CG2   . VAL A 1 213 ? 221.996 213.877 215.587 1.00 21.40  ? 213 VAL A CG2   1 
ATOM   1475  N  N     . CYS A 1 214 ? 224.562 210.732 213.443 1.00 22.47  ? 214 CYS A N     1 
ATOM   1476  C  CA    . CYS A 1 214 ? 225.121 209.920 212.366 1.00 25.04  ? 214 CYS A CA    1 
ATOM   1477  C  C     . CYS A 1 214 ? 224.852 208.431 212.581 1.00 22.54  ? 214 CYS A C     1 
ATOM   1478  O  O     . CYS A 1 214 ? 224.491 207.729 211.649 1.00 21.95  ? 214 CYS A O     1 
ATOM   1479  C  CB    . CYS A 1 214 ? 226.620 210.154 212.221 1.00 28.74  ? 214 CYS A CB    1 
ATOM   1480  S  SG    . CYS A 1 214 ? 226.993 211.848 211.723 1.00 40.50  ? 214 CYS A SG    1 
ATOM   1481  N  N     . ASN A 1 215 ? 225.024 207.961 213.818 1.00 21.13  ? 215 ASN A N     1 
ATOM   1482  C  CA    . ASN A 1 215 ? 224.805 206.563 214.135 1.00 20.40  ? 215 ASN A CA    1 
ATOM   1483  C  C     . ASN A 1 215 ? 223.342 206.182 213.942 1.00 18.32  ? 215 ASN A C     1 
ATOM   1484  O  O     . ASN A 1 215 ? 223.046 205.106 213.425 1.00 19.08  ? 215 ASN A O     1 
ATOM   1485  C  CB    . ASN A 1 215 ? 225.252 206.241 215.556 1.00 23.11  ? 215 ASN A CB    1 
ATOM   1486  C  CG    . ASN A 1 215 ? 226.731 206.460 215.759 1.00 25.80  ? 215 ASN A CG    1 
ATOM   1487  O  OD1   . ASN A 1 215 ? 227.491 206.589 214.793 1.00 27.29  ? 215 ASN A OD1   1 
ATOM   1488  N  ND2   . ASN A 1 215 ? 227.152 206.525 217.012 1.00 28.61  ? 215 ASN A ND2   1 
ATOM   1489  N  N     . PHE A 1 216 ? 222.421 207.050 214.365 1.00 16.56  ? 216 PHE A N     1 
ATOM   1490  C  CA    . PHE A 1 216 ? 221.006 206.759 214.210 1.00 15.67  ? 216 PHE A CA    1 
ATOM   1491  C  C     . PHE A 1 216 ? 220.642 206.685 212.722 1.00 14.47  ? 216 PHE A C     1 
ATOM   1492  O  O     . PHE A 1 216 ? 219.912 205.782 212.296 1.00 13.68  ? 216 PHE A O     1 
ATOM   1493  C  CB    . PHE A 1 216 ? 220.143 207.821 214.904 1.00 14.71  ? 216 PHE A CB    1 
ATOM   1494  C  CG    . PHE A 1 216 ? 218.682 207.703 214.520 1.00 13.98  ? 216 PHE A CG    1 
ATOM   1495  C  CD1   . PHE A 1 216 ? 217.903 206.684 215.047 1.00 13.88  ? 216 PHE A CD1   1 
ATOM   1496  C  CD2   . PHE A 1 216 ? 218.102 208.572 213.604 1.00 14.20  ? 216 PHE A CD2   1 
ATOM   1497  C  CE1   . PHE A 1 216 ? 216.577 206.548 214.669 1.00 13.90  ? 216 PHE A CE1   1 
ATOM   1498  C  CE2   . PHE A 1 216 ? 216.783 208.420 213.224 1.00 13.70  ? 216 PHE A CE2   1 
ATOM   1499  C  CZ    . PHE A 1 216 ? 216.022 207.428 213.763 1.00 13.71  ? 216 PHE A CZ    1 
ATOM   1500  N  N     . LEU A 1 217 ? 221.132 207.644 211.938 1.00 15.26  ? 217 LEU A N     1 
ATOM   1501  C  CA    . LEU A 1 217 ? 220.826 207.678 210.516 1.00 16.73  ? 217 LEU A CA    1 
ATOM   1502  C  C     . LEU A 1 217 ? 221.375 206.432 209.824 1.00 16.43  ? 217 LEU A C     1 
ATOM   1503  O  O     . LEU A 1 217 ? 220.709 205.855 208.964 1.00 17.47  ? 217 LEU A O     1 
ATOM   1504  C  CB    . LEU A 1 217 ? 221.367 208.948 209.871 1.00 17.65  ? 217 LEU A CB    1 
ATOM   1505  C  CG    . LEU A 1 217 ? 220.652 210.250 210.243 1.00 19.05  ? 217 LEU A CG    1 
ATOM   1506  C  CD1   . LEU A 1 217 ? 221.395 211.439 209.647 1.00 19.36  ? 217 LEU A CD1   1 
ATOM   1507  C  CD2   . LEU A 1 217 ? 219.200 210.253 209.804 1.00 19.99  ? 217 LEU A CD2   1 
ATOM   1508  N  N     . ALA A 1 218 ? 222.589 206.023 210.194 1.00 17.46  ? 218 ALA A N     1 
ATOM   1509  C  CA    . ALA A 1 218 ? 223.202 204.832 209.619 1.00 18.62  ? 218 ALA A CA    1 
ATOM   1510  C  C     . ALA A 1 218 ? 222.378 203.601 209.958 1.00 18.83  ? 218 ALA A C     1 
ATOM   1511  O  O     . ALA A 1 218 ? 222.224 202.715 209.119 1.00 19.91  ? 218 ALA A O     1 
ATOM   1512  C  CB    . ALA A 1 218 ? 224.627 204.673 210.107 1.00 18.95  ? 218 ALA A CB    1 
ATOM   1513  N  N     . SER A 1 219 ? 221.838 203.538 211.183 1.00 17.99  ? 219 SER A N     1 
ATOM   1514  C  CA    . SER A 1 219 ? 221.010 202.417 211.596 1.00 17.60  ? 219 SER A CA    1 
ATOM   1515  C  C     . SER A 1 219 ? 219.684 202.380 210.837 1.00 16.02  ? 219 SER A C     1 
ATOM   1516  O  O     . SER A 1 219 ? 219.032 201.344 210.800 1.00 17.90  ? 219 SER A O     1 
ATOM   1517  C  CB    . SER A 1 219 ? 220.782 202.444 213.090 1.00 18.27  ? 219 SER A CB    1 
ATOM   1518  O  OG    . SER A 1 219 ? 219.889 203.490 213.451 1.00 18.27  ? 219 SER A OG    1 
ATOM   1519  N  N     . GLN A 1 220 ? 219.272 203.507 210.248 1.00 14.85  ? 220 GLN A N     1 
ATOM   1520  C  CA    . GLN A 1 220 ? 218.003 203.569 209.543 1.00 14.42  ? 220 GLN A CA    1 
ATOM   1521  C  C     . GLN A 1 220 ? 218.124 203.204 208.069 1.00 13.69  ? 220 GLN A C     1 
ATOM   1522  O  O     . GLN A 1 220 ? 217.108 203.141 207.385 1.00 14.65  ? 220 GLN A O     1 
ATOM   1523  C  CB    . GLN A 1 220 ? 217.385 204.963 209.661 1.00 15.15  ? 220 GLN A CB    1 
ATOM   1524  C  CG    . GLN A 1 220 ? 216.856 205.253 211.064 1.00 15.78  ? 220 GLN A CG    1 
ATOM   1525  C  CD    . GLN A 1 220 ? 216.203 204.053 211.717 1.00 17.26  ? 220 GLN A CD    1 
ATOM   1526  O  OE1   . GLN A 1 220 ? 215.163 203.555 211.276 1.00 18.76  ? 220 GLN A OE1   1 
ATOM   1527  N  NE2   . GLN A 1 220 ? 216.855 203.528 212.742 1.00 18.67  ? 220 GLN A NE2   1 
ATOM   1528  N  N     . VAL A 1 221 ? 219.330 202.969 207.563 1.00 12.43  ? 221 VAL A N     1 
ATOM   1529  C  CA    . VAL A 1 221 ? 219.486 202.431 206.218 1.00 11.83  ? 221 VAL A CA    1 
ATOM   1530  C  C     . VAL A 1 221 ? 219.014 200.979 206.237 1.00 11.45  ? 221 VAL A C     1 
ATOM   1531  O  O     . VAL A 1 221 ? 219.486 200.199 207.059 1.00 11.42  ? 221 VAL A O     1 
ATOM   1532  C  CB    . VAL A 1 221 ? 220.941 202.514 205.731 1.00 11.40  ? 221 VAL A CB    1 
ATOM   1533  C  CG1   . VAL A 1 221 ? 221.072 202.041 204.289 1.00 11.50  ? 221 VAL A CG1   1 
ATOM   1534  C  CG2   . VAL A 1 221 ? 221.483 203.923 205.887 1.00 11.24  ? 221 VAL A CG2   1 
ATOM   1535  N  N     . PRO A 1 222 ? 217.997 200.593 205.440 1.00 11.13  ? 222 PRO A N     1 
ATOM   1536  C  CA    . PRO A 1 222 ? 217.446 199.239 205.507 1.00 11.59  ? 222 PRO A CA    1 
ATOM   1537  C  C     . PRO A 1 222 ? 218.510 198.153 205.384 1.00 11.24  ? 222 PRO A C     1 
ATOM   1538  O  O     . PRO A 1 222 ? 218.650 197.329 206.281 1.00 11.91  ? 222 PRO A O     1 
ATOM   1539  C  CB    . PRO A 1 222 ? 216.444 199.203 204.360 1.00 11.45  ? 222 PRO A CB    1 
ATOM   1540  C  CG    . PRO A 1 222 ? 216.011 200.633 204.244 1.00 11.63  ? 222 PRO A CG    1 
ATOM   1541  C  CD    . PRO A 1 222 ? 217.241 201.460 204.531 1.00 11.68  ? 222 PRO A CD    1 
ATOM   1542  N  N     . PHE A 1 223 ? 219.251 198.152 204.268 1.00 11.28  ? 223 PHE A N     1 
ATOM   1543  C  CA    . PHE A 1 223 ? 220.353 197.208 204.142 1.00 10.98  ? 223 PHE A CA    1 
ATOM   1544  C  C     . PHE A 1 223 ? 221.310 197.666 203.048 1.00 11.21  ? 223 PHE A C     1 
ATOM   1545  O  O     . PHE A 1 223 ? 220.881 197.995 201.941 1.00 11.41  ? 223 PHE A O     1 
ATOM   1546  C  CB    . PHE A 1 223 ? 219.846 195.788 203.835 1.00 10.76  ? 223 PHE A CB    1 
ATOM   1547  C  CG    . PHE A 1 223 ? 220.986 194.786 203.761 1.00 10.58  ? 223 PHE A CG    1 
ATOM   1548  C  CD1   . PHE A 1 223 ? 221.567 194.282 204.918 1.00 10.54  ? 223 PHE A CD1   1 
ATOM   1549  C  CD2   . PHE A 1 223 ? 221.506 194.392 202.533 1.00 10.83  ? 223 PHE A CD2   1 
ATOM   1550  C  CE1   . PHE A 1 223 ? 222.657 193.432 204.846 1.00 11.04  ? 223 PHE A CE1   1 
ATOM   1551  C  CE2   . PHE A 1 223 ? 222.603 193.548 202.471 1.00 11.12  ? 223 PHE A CE2   1 
ATOM   1552  C  CZ    . PHE A 1 223 ? 223.171 193.068 203.619 1.00 11.18  ? 223 PHE A CZ    1 
ATOM   1553  N  N     . PRO A 1 224 ? 222.642 197.671 203.298 1.00 12.38  ? 224 PRO A N     1 
ATOM   1554  C  CA    . PRO A 1 224 ? 223.233 197.402 204.615 1.00 12.90  ? 224 PRO A CA    1 
ATOM   1555  C  C     . PRO A 1 224 ? 223.052 198.576 205.577 1.00 13.63  ? 224 PRO A C     1 
ATOM   1556  O  O     . PRO A 1 224 ? 223.083 199.729 205.159 1.00 13.94  ? 224 PRO A O     1 
ATOM   1557  C  CB    . PRO A 1 224 ? 224.716 197.148 204.280 1.00 13.63  ? 224 PRO A CB    1 
ATOM   1558  C  CG    . PRO A 1 224 ? 224.961 197.970 203.044 1.00 13.27  ? 224 PRO A CG    1 
ATOM   1559  C  CD    . PRO A 1 224 ? 223.653 197.934 202.269 1.00 12.91  ? 224 PRO A CD    1 
ATOM   1560  N  N     . SER A 1 225 ? 222.862 198.282 206.867 1.00 14.58  ? 225 SER A N     1 
ATOM   1561  C  CA    . SER A 1 225 ? 222.571 199.307 207.856 1.00 15.46  ? 225 SER A CA    1 
ATOM   1562  C  C     . SER A 1 225 ? 223.858 200.002 208.284 1.00 14.58  ? 225 SER A C     1 
ATOM   1563  O  O     . SER A 1 225 ? 224.371 199.782 209.380 1.00 16.37  ? 225 SER A O     1 
ATOM   1564  C  CB    . SER A 1 225 ? 221.832 198.729 209.041 1.00 17.46  ? 225 SER A CB    1 
ATOM   1565  O  OG    . SER A 1 225 ? 220.585 198.183 208.626 1.00 17.91  ? 225 SER A OG    1 
ATOM   1566  N  N     . ARG A 1 226 ? 224.390 200.816 207.381 1.00 14.38  ? 226 ARG A N     1 
ATOM   1567  C  CA    . ARG A 1 226 ? 225.618 201.543 207.641 1.00 14.73  ? 226 ARG A CA    1 
ATOM   1568  C  C     . ARG A 1 226 ? 225.681 202.720 206.684 1.00 14.46  ? 226 ARG A C     1 
ATOM   1569  O  O     . ARG A 1 226 ? 224.924 202.790 205.723 1.00 14.52  ? 226 ARG A O     1 
ATOM   1570  C  CB    . ARG A 1 226 ? 226.843 200.631 207.490 1.00 15.36  ? 226 ARG A CB    1 
ATOM   1571  C  CG    . ARG A 1 226 ? 226.916 199.935 206.138 1.00 17.05  ? 226 ARG A CG    1 
ATOM   1572  C  CD    . ARG A 1 226 ? 228.304 199.461 205.822 1.00 17.60  ? 226 ARG A CD    1 
ATOM   1573  N  NE    . ARG A 1 226 ? 228.326 198.699 204.568 1.00 18.45  ? 226 ARG A NE    1 
ATOM   1574  C  CZ    . ARG A 1 226 ? 228.388 199.203 203.346 1.00 18.69  ? 226 ARG A CZ    1 
ATOM   1575  N  NH1   . ARG A 1 226 ? 228.454 200.508 203.165 1.00 19.08  ? 226 ARG A NH1   1 
ATOM   1576  N  NH2   . ARG A 1 226 ? 228.386 198.394 202.306 1.00 19.41  ? 226 ARG A NH2   1 
ATOM   1577  N  N     . LEU A 1 227 ? 226.621 203.626 206.933 1.00 14.93  ? 227 LEU A N     1 
ATOM   1578  C  CA    . LEU A 1 227 ? 226.884 204.692 205.992 1.00 15.05  ? 227 LEU A CA    1 
ATOM   1579  C  C     . LEU A 1 227 ? 227.450 204.090 204.710 1.00 14.05  ? 227 LEU A C     1 
ATOM   1580  O  O     . LEU A 1 227 ? 228.211 203.131 204.726 1.00 13.04  ? 227 LEU A O     1 
ATOM   1581  C  CB    . LEU A 1 227 ? 227.850 205.704 206.606 1.00 16.81  ? 227 LEU A CB    1 
ATOM   1582  C  CG    . LEU A 1 227 ? 227.301 206.538 207.759 1.00 18.18  ? 227 LEU A CG    1 
ATOM   1583  C  CD1   . LEU A 1 227 ? 228.360 207.520 208.223 1.00 19.38  ? 227 LEU A CD1   1 
ATOM   1584  C  CD2   . LEU A 1 227 ? 226.035 207.246 207.332 1.00 19.26  ? 227 LEU A CD2   1 
ATOM   1585  N  N     . GLY A 1 228 ? 227.144 204.736 203.595 1.00 13.26  ? 228 GLY A N     1 
ATOM   1586  C  CA    . GLY A 1 228 ? 227.738 204.364 202.337 1.00 13.97  ? 228 GLY A CA    1 
ATOM   1587  C  C     . GLY A 1 228 ? 229.261 204.531 202.346 1.00 15.05  ? 228 GLY A C     1 
ATOM   1588  O  O     . GLY A 1 228 ? 229.795 205.544 202.773 1.00 15.31  ? 228 GLY A O     1 
ATOM   1589  N  N     . ASP A 1 229 ? 229.947 203.520 201.819 1.00 16.08  ? 229 ASP A N     1 
ATOM   1590  C  CA    . ASP A 1 229 ? 231.378 203.586 201.614 1.00 17.13  ? 229 ASP A CA    1 
ATOM   1591  C  C     . ASP A 1 229 ? 231.663 204.363 200.330 1.00 15.43  ? 229 ASP A C     1 
ATOM   1592  O  O     . ASP A 1 229 ? 231.098 204.078 199.276 1.00 14.62  ? 229 ASP A O     1 
ATOM   1593  C  CB    . ASP A 1 229 ? 231.947 202.187 201.504 1.00 21.01  ? 229 ASP A CB    1 
ATOM   1594  C  CG    . ASP A 1 229 ? 233.460 202.114 201.624 1.00 25.10  ? 229 ASP A CG    1 
ATOM   1595  O  OD1   . ASP A 1 229 ? 234.106 203.181 201.590 1.00 27.34  ? 229 ASP A OD1   1 
ATOM   1596  O  OD2   . ASP A 1 229 ? 233.973 200.981 201.715 1.00 28.54  ? 229 ASP A OD2   1 
ATOM   1597  N  N     . PRO A 1 230 ? 232.515 205.409 200.367 1.00 14.67  ? 230 PRO A N     1 
ATOM   1598  C  CA    . PRO A 1 230 ? 232.854 206.143 199.149 1.00 14.26  ? 230 PRO A CA    1 
ATOM   1599  C  C     . PRO A 1 230 ? 233.352 205.279 197.996 1.00 12.92  ? 230 PRO A C     1 
ATOM   1600  O  O     . PRO A 1 230 ? 233.146 205.637 196.844 1.00 14.34  ? 230 PRO A O     1 
ATOM   1601  C  CB    . PRO A 1 230 ? 233.917 207.138 199.627 1.00 14.61  ? 230 PRO A CB    1 
ATOM   1602  C  CG    . PRO A 1 230 ? 233.515 207.409 201.040 1.00 14.89  ? 230 PRO A CG    1 
ATOM   1603  C  CD    . PRO A 1 230 ? 233.092 206.039 201.565 1.00 15.09  ? 230 PRO A CD    1 
ATOM   1604  N  N     . ALA A 1 231 ? 234.006 204.158 198.293 1.00 13.07  ? 231 ALA A N     1 
ATOM   1605  C  CA    . ALA A 1 231 ? 234.423 203.219 197.261 1.00 13.18  ? 231 ALA A CA    1 
ATOM   1606  C  C     . ALA A 1 231 ? 233.222 202.639 196.511 1.00 12.95  ? 231 ALA A C     1 
ATOM   1607  O  O     . ALA A 1 231 ? 233.308 202.350 195.320 1.00 12.70  ? 231 ALA A O     1 
ATOM   1608  C  CB    . ALA A 1 231 ? 235.256 202.109 197.853 1.00 14.12  ? 231 ALA A CB    1 
ATOM   1609  N  N     . GLU A 1 232 ? 232.084 202.500 197.201 1.00 13.04  ? 232 GLU A N     1 
ATOM   1610  C  CA    . GLU A 1 232 ? 230.863 202.024 196.571 1.00 13.22  ? 232 GLU A CA    1 
ATOM   1611  C  C     . GLU A 1 232 ? 230.350 203.038 195.554 1.00 11.75  ? 232 GLU A C     1 
ATOM   1612  O  O     . GLU A 1 232 ? 229.838 202.664 194.495 1.00 11.09  ? 232 GLU A O     1 
ATOM   1613  C  CB    . GLU A 1 232 ? 229.826 201.722 197.644 1.00 15.60  ? 232 GLU A CB    1 
ATOM   1614  C  CG    . GLU A 1 232 ? 230.279 200.547 198.508 1.00 18.54  ? 232 GLU A CG    1 
ATOM   1615  C  CD    . GLU A 1 232 ? 229.498 200.366 199.772 1.00 20.92  ? 232 GLU A CD    1 
ATOM   1616  O  OE1   . GLU A 1 232 ? 228.661 201.222 200.065 1.00 21.82  ? 232 GLU A OE1   1 
ATOM   1617  O  OE2   . GLU A 1 232 ? 229.734 199.350 200.448 1.00 27.41  ? 232 GLU A OE2   1 
ATOM   1618  N  N     . TYR A 1 233 ? 230.483 204.328 195.873 1.00 9.96   ? 233 TYR A N     1 
ATOM   1619  C  CA    . TYR A 1 233 ? 230.170 205.365 194.908 1.00 9.43   ? 233 TYR A CA    1 
ATOM   1620  C  C     . TYR A 1 233 ? 231.093 205.249 193.701 1.00 8.77   ? 233 TYR A C     1 
ATOM   1621  O  O     . TYR A 1 233 ? 230.649 205.381 192.562 1.00 8.19   ? 233 TYR A O     1 
ATOM   1622  C  CB    . TYR A 1 233 ? 230.266 206.738 195.571 1.00 9.65   ? 233 TYR A CB    1 
ATOM   1623  C  CG    . TYR A 1 233 ? 230.117 207.906 194.616 1.00 10.20  ? 233 TYR A CG    1 
ATOM   1624  C  CD1   . TYR A 1 233 ? 231.215 208.452 193.962 1.00 10.65  ? 233 TYR A CD1   1 
ATOM   1625  C  CD2   . TYR A 1 233 ? 228.877 208.465 194.385 1.00 10.72  ? 233 TYR A CD2   1 
ATOM   1626  C  CE1   . TYR A 1 233 ? 231.079 209.521 193.097 1.00 11.02  ? 233 TYR A CE1   1 
ATOM   1627  C  CE2   . TYR A 1 233 ? 228.722 209.527 193.514 1.00 10.81  ? 233 TYR A CE2   1 
ATOM   1628  C  CZ    . TYR A 1 233 ? 229.830 210.069 192.883 1.00 11.74  ? 233 TYR A CZ    1 
ATOM   1629  O  OH    . TYR A 1 233 ? 229.690 211.130 192.035 1.00 12.00  ? 233 TYR A OH    1 
ATOM   1630  N  N     . ALA A 1 234 ? 232.395 205.047 193.950 1.00 8.27   ? 234 ALA A N     1 
ATOM   1631  C  CA    . ALA A 1 234 ? 233.370 204.935 192.877 1.00 7.94   ? 234 ALA A CA    1 
ATOM   1632  C  C     . ALA A 1 234 ? 233.051 203.743 191.974 1.00 7.64   ? 234 ALA A C     1 
ATOM   1633  O  O     . ALA A 1 234 ? 233.203 203.828 190.759 1.00 7.51   ? 234 ALA A O     1 
ATOM   1634  C  CB    . ALA A 1 234 ? 234.776 204.827 193.439 1.00 7.86   ? 234 ALA A CB    1 
ATOM   1635  N  N     . HIS A 1 235 ? 232.616 202.637 192.570 1.00 7.80   ? 235 HIS A N     1 
ATOM   1636  C  CA    . HIS A 1 235 ? 232.257 201.459 191.793 1.00 8.27   ? 235 HIS A CA    1 
ATOM   1637  C  C     . HIS A 1 235 ? 231.112 201.763 190.830 1.00 7.36   ? 235 HIS A C     1 
ATOM   1638  O  O     . HIS A 1 235 ? 231.144 201.339 189.678 1.00 6.81   ? 235 HIS A O     1 
ATOM   1639  C  CB    . HIS A 1 235 ? 231.901 200.299 192.722 1.00 9.32   ? 235 HIS A CB    1 
ATOM   1640  C  CG    . HIS A 1 235 ? 231.474 199.063 192.000 1.00 11.06  ? 235 HIS A CG    1 
ATOM   1641  N  ND1   . HIS A 1 235 ? 230.151 198.868 191.646 1.00 11.96  ? 235 HIS A ND1   1 
ATOM   1642  C  CD2   . HIS A 1 235 ? 232.155 197.984 191.551 1.00 11.72  ? 235 HIS A CD2   1 
ATOM   1643  C  CE1   . HIS A 1 235 ? 230.049 197.706 191.000 1.00 12.94  ? 235 HIS A CE1   1 
ATOM   1644  N  NE2   . HIS A 1 235 ? 231.252 197.155 190.939 1.00 12.33  ? 235 HIS A NE2   1 
ATOM   1645  N  N     . LEU A 1 236 ? 230.090 202.487 191.306 1.00 6.85   ? 236 LEU A N     1 
ATOM   1646  C  CA    . LEU A 1 236 ? 228.975 202.844 190.457 1.00 6.87   ? 236 LEU A CA    1 
ATOM   1647  C  C     . LEU A 1 236 ? 229.434 203.782 189.340 1.00 6.72   ? 236 LEU A C     1 
ATOM   1648  O  O     . LEU A 1 236 ? 228.948 203.690 188.218 1.00 6.50   ? 236 LEU A O     1 
ATOM   1649  C  CB    . LEU A 1 236 ? 227.847 203.466 191.276 1.00 7.31   ? 236 LEU A CB    1 
ATOM   1650  C  CG    . LEU A 1 236 ? 226.615 203.929 190.495 1.00 7.39   ? 236 LEU A CG    1 
ATOM   1651  C  CD1   . LEU A 1 236 ? 226.034 202.783 189.689 1.00 7.47   ? 236 LEU A CD1   1 
ATOM   1652  C  CD2   . LEU A 1 236 ? 225.579 204.523 191.435 1.00 7.51   ? 236 LEU A CD2   1 
ATOM   1653  N  N     . VAL A 1 237 ? 230.341 204.718 189.652 1.00 7.06   ? 237 VAL A N     1 
ATOM   1654  C  CA    . VAL A 1 237 ? 230.851 205.626 188.640 1.00 7.52   ? 237 VAL A CA    1 
ATOM   1655  C  C     . VAL A 1 237 ? 231.508 204.825 187.516 1.00 7.65   ? 237 VAL A C     1 
ATOM   1656  O  O     . VAL A 1 237 ? 231.290 205.095 186.338 1.00 7.95   ? 237 VAL A O     1 
ATOM   1657  C  CB    . VAL A 1 237 ? 231.836 206.643 189.249 1.00 7.78   ? 237 VAL A CB    1 
ATOM   1658  C  CG1   . VAL A 1 237 ? 232.670 207.317 188.175 1.00 8.06   ? 237 VAL A CG1   1 
ATOM   1659  C  CG2   . VAL A 1 237 ? 231.123 207.680 190.089 1.00 7.76   ? 237 VAL A CG2   1 
ATOM   1660  N  N     . GLN A 1 238 ? 232.339 203.848 187.870 1.00 8.20   ? 238 GLN A N     1 
ATOM   1661  C  CA    . GLN A 1 238 ? 232.982 203.025 186.859 1.00 9.05   ? 238 GLN A CA    1 
ATOM   1662  C  C     . GLN A 1 238 ? 231.958 202.238 186.035 1.00 8.41   ? 238 GLN A C     1 
ATOM   1663  O  O     . GLN A 1 238 ? 232.084 202.134 184.821 1.00 8.66   ? 238 GLN A O     1 
ATOM   1664  C  CB    . GLN A 1 238 ? 233.982 202.077 187.514 1.00 10.34  ? 238 GLN A CB    1 
ATOM   1665  C  CG    . GLN A 1 238 ? 234.715 201.194 186.509 1.00 12.06  ? 238 GLN A CG    1 
ATOM   1666  C  CD    . GLN A 1 238 ? 235.750 200.317 187.170 1.00 14.13  ? 238 GLN A CD    1 
ATOM   1667  O  OE1   . GLN A 1 238 ? 236.035 200.446 188.364 1.00 15.21  ? 238 GLN A OE1   1 
ATOM   1668  N  NE2   . GLN A 1 238 ? 236.316 199.405 186.395 1.00 16.10  ? 238 GLN A NE2   1 
ATOM   1669  N  N     . ALA A 1 239 ? 230.931 201.698 186.696 1.00 8.11   ? 239 ALA A N     1 
ATOM   1670  C  CA    . ALA A 1 239 ? 229.880 200.976 185.992 1.00 7.85   ? 239 ALA A CA    1 
ATOM   1671  C  C     . ALA A 1 239 ? 229.185 201.880 184.974 1.00 7.89   ? 239 ALA A C     1 
ATOM   1672  O  O     . ALA A 1 239 ? 228.876 201.442 183.871 1.00 8.22   ? 239 ALA A O     1 
ATOM   1673  C  CB    . ALA A 1 239 ? 228.892 200.404 186.978 1.00 7.91   ? 239 ALA A CB    1 
ATOM   1674  N  N     . ILE A 1 240 ? 228.941 203.147 185.338 1.00 7.86   ? 240 ILE A N     1 
ATOM   1675  C  CA    . ILE A 1 240 ? 228.314 204.081 184.423 1.00 7.96   ? 240 ILE A CA    1 
ATOM   1676  C  C     . ILE A 1 240 ? 229.222 204.360 183.229 1.00 8.58   ? 240 ILE A C     1 
ATOM   1677  O  O     . ILE A 1 240 ? 228.757 204.413 182.089 1.00 8.94   ? 240 ILE A O     1 
ATOM   1678  C  CB    . ILE A 1 240 ? 227.915 205.375 185.146 1.00 8.07   ? 240 ILE A CB    1 
ATOM   1679  C  CG1   . ILE A 1 240 ? 226.804 205.130 186.137 1.00 8.24   ? 240 ILE A CG1   1 
ATOM   1680  C  CG2   . ILE A 1 240 ? 227.532 206.464 184.139 1.00 8.01   ? 240 ILE A CG2   1 
ATOM   1681  C  CD1   . ILE A 1 240 ? 226.577 206.294 187.082 1.00 8.46   ? 240 ILE A CD1   1 
ATOM   1682  N  N     . ILE A 1 241 ? 230.521 204.528 183.486 1.00 9.25   ? 241 ILE A N     1 
ATOM   1683  C  CA    . ILE A 1 241 ? 231.464 204.786 182.410 1.00 9.77   ? 241 ILE A CA    1 
ATOM   1684  C  C     . ILE A 1 241 ? 231.489 203.602 181.444 1.00 10.63  ? 241 ILE A C     1 
ATOM   1685  O  O     . ILE A 1 241 ? 231.504 203.786 180.231 1.00 10.90  ? 241 ILE A O     1 
ATOM   1686  C  CB    . ILE A 1 241 ? 232.861 205.096 182.973 1.00 9.71   ? 241 ILE A CB    1 
ATOM   1687  C  CG1   . ILE A 1 241 ? 232.854 206.383 183.781 1.00 9.64   ? 241 ILE A CG1   1 
ATOM   1688  C  CG2   . ILE A 1 241 ? 233.907 205.143 181.860 1.00 9.89   ? 241 ILE A CG2   1 
ATOM   1689  C  CD1   . ILE A 1 241 ? 234.056 206.539 184.678 1.00 9.40   ? 241 ILE A CD1   1 
ATOM   1690  N  N     . GLU A 1 242 ? 231.499 202.386 181.982 1.00 12.26  ? 242 GLU A N     1 
ATOM   1691  C  CA    . GLU A 1 242 ? 231.664 201.191 181.165 1.00 14.08  ? 242 GLU A CA    1 
ATOM   1692  C  C     . GLU A 1 242 ? 230.388 200.826 180.403 1.00 13.88  ? 242 GLU A C     1 
ATOM   1693  O  O     . GLU A 1 242 ? 230.471 200.143 179.388 1.00 16.31  ? 242 GLU A O     1 
ATOM   1694  C  CB    . GLU A 1 242 ? 232.120 200.022 182.033 1.00 16.19  ? 242 GLU A CB    1 
ATOM   1695  C  CG    . GLU A 1 242 ? 233.483 200.261 182.682 1.00 19.92  ? 242 GLU A CG    1 
ATOM   1696  C  CD    . GLU A 1 242 ? 234.001 199.066 183.446 1.00 25.13  ? 242 GLU A CD    1 
ATOM   1697  O  OE1   . GLU A 1 242 ? 235.199 198.742 183.266 1.00 32.45  ? 242 GLU A OE1   1 
ATOM   1698  O  OE2   . GLU A 1 242 ? 233.207 198.407 184.148 1.00 29.38  ? 242 GLU A OE2   1 
ATOM   1699  N  N     . ASN A 1 243 ? 229.213 201.234 180.889 1.00 13.25  ? 243 ASN A N     1 
ATOM   1700  C  CA    . ASN A 1 243 ? 227.955 200.834 180.280 1.00 12.73  ? 243 ASN A CA    1 
ATOM   1701  C  C     . ASN A 1 243 ? 227.529 201.885 179.267 1.00 12.96  ? 243 ASN A C     1 
ATOM   1702  O  O     . ASN A 1 243 ? 227.154 202.987 179.650 1.00 13.84  ? 243 ASN A O     1 
ATOM   1703  C  CB    . ASN A 1 243 ? 226.867 200.632 181.328 1.00 12.36  ? 243 ASN A CB    1 
ATOM   1704  C  CG    . ASN A 1 243 ? 225.689 199.845 180.802 1.00 11.38  ? 243 ASN A CG    1 
ATOM   1705  O  OD1   . ASN A 1 243 ? 225.049 200.244 179.829 1.00 11.84  ? 243 ASN A OD1   1 
ATOM   1706  N  ND2   . ASN A 1 243 ? 225.385 198.714 181.407 1.00 11.14  ? 243 ASN A ND2   1 
ATOM   1707  N  N     . PRO A 1 244 ? 227.575 201.603 177.948 1.00 13.40  ? 244 PRO A N     1 
ATOM   1708  C  CA    . PRO A 1 244 ? 227.281 202.626 176.945 1.00 13.91  ? 244 PRO A CA    1 
ATOM   1709  C  C     . PRO A 1 244 ? 225.825 203.060 176.843 1.00 13.41  ? 244 PRO A C     1 
ATOM   1710  O  O     . PRO A 1 244 ? 225.526 204.020 176.151 1.00 13.53  ? 244 PRO A O     1 
ATOM   1711  C  CB    . PRO A 1 244 ? 227.739 201.990 175.625 1.00 14.66  ? 244 PRO A CB    1 
ATOM   1712  C  CG    . PRO A 1 244 ? 228.521 200.775 176.032 1.00 15.11  ? 244 PRO A CG    1 
ATOM   1713  C  CD    . PRO A 1 244 ? 227.949 200.321 177.342 1.00 14.39  ? 244 PRO A CD    1 
ATOM   1714  N  N     . PHE A 1 245 ? 224.912 202.344 177.506 1.00 12.90  ? 245 PHE A N     1 
ATOM   1715  C  CA    . PHE A 1 245 ? 223.498 202.577 177.282 1.00 13.10  ? 245 PHE A CA    1 
ATOM   1716  C  C     . PHE A 1 245 ? 222.810 203.241 178.467 1.00 11.77  ? 245 PHE A C     1 
ATOM   1717  O  O     . PHE A 1 245 ? 221.602 203.463 178.406 1.00 13.13  ? 245 PHE A O     1 
ATOM   1718  C  CB    . PHE A 1 245 ? 222.825 201.254 176.923 1.00 13.80  ? 245 PHE A CB    1 
ATOM   1719  C  CG    . PHE A 1 245 ? 221.581 201.455 176.082 1.00 14.86  ? 245 PHE A CG    1 
ATOM   1720  C  CD1   . PHE A 1 245 ? 221.655 201.986 174.797 1.00 15.74  ? 245 PHE A CD1   1 
ATOM   1721  C  CD2   . PHE A 1 245 ? 220.340 201.175 176.618 1.00 16.31  ? 245 PHE A CD2   1 
ATOM   1722  C  CE1   . PHE A 1 245 ? 220.502 202.156 174.037 1.00 15.69  ? 245 PHE A CE1   1 
ATOM   1723  C  CE2   . PHE A 1 245 ? 219.195 201.363 175.871 1.00 16.17  ? 245 PHE A CE2   1 
ATOM   1724  C  CZ    . PHE A 1 245 ? 219.272 201.835 174.575 1.00 15.95  ? 245 PHE A CZ    1 
ATOM   1725  N  N     . LEU A 1 246 ? 223.582 203.588 179.501 1.00 11.06  ? 246 LEU A N     1 
ATOM   1726  C  CA    . LEU A 1 246 ? 223.090 204.382 180.620 1.00 10.14  ? 246 LEU A CA    1 
ATOM   1727  C  C     . LEU A 1 246 ? 223.220 205.851 180.244 1.00 9.37   ? 246 LEU A C     1 
ATOM   1728  O  O     . LEU A 1 246 ? 224.330 206.350 180.070 1.00 9.26   ? 246 LEU A O     1 
ATOM   1729  C  CB    . LEU A 1 246 ? 223.879 204.090 181.896 1.00 10.03  ? 246 LEU A CB    1 
ATOM   1730  C  CG    . LEU A 1 246 ? 223.485 202.858 182.702 1.00 9.88   ? 246 LEU A CG    1 
ATOM   1731  C  CD1   . LEU A 1 246 ? 224.523 202.582 183.761 1.00 10.17  ? 246 LEU A CD1   1 
ATOM   1732  C  CD2   . LEU A 1 246 ? 222.103 203.033 183.351 1.00 9.79   ? 246 LEU A CD2   1 
ATOM   1733  N  N     . ASN A 1 247 ? 222.089 206.549 180.151 1.00 8.87   ? 247 ASN A N     1 
ATOM   1734  C  CA    . ASN A 1 247 ? 222.101 207.939 179.759 1.00 8.86   ? 247 ASN A CA    1 
ATOM   1735  C  C     . ASN A 1 247 ? 220.858 208.643 180.289 1.00 8.85   ? 247 ASN A C     1 
ATOM   1736  O  O     . ASN A 1 247 ? 219.770 208.087 180.283 1.00 9.54   ? 247 ASN A O     1 
ATOM   1737  C  CB    . ASN A 1 247 ? 222.203 208.068 178.249 1.00 8.71   ? 247 ASN A CB    1 
ATOM   1738  C  CG    . ASN A 1 247 ? 222.681 209.422 177.802 1.00 8.60   ? 247 ASN A CG    1 
ATOM   1739  O  OD1   . ASN A 1 247 ? 223.130 210.230 178.621 1.00 9.45   ? 247 ASN A OD1   1 
ATOM   1740  N  ND2   . ASN A 1 247 ? 222.619 209.668 176.511 1.00 8.38   ? 247 ASN A ND2   1 
ATOM   1741  N  N     . GLY A 1 248 ? 221.039 209.875 180.762 1.00 8.74   ? 248 GLY A N     1 
ATOM   1742  C  CA    . GLY A 1 248 ? 219.930 210.730 181.147 1.00 8.83   ? 248 GLY A CA    1 
ATOM   1743  C  C     . GLY A 1 248 ? 219.144 210.205 182.338 1.00 9.08   ? 248 GLY A C     1 
ATOM   1744  O  O     . GLY A 1 248 ? 217.958 210.490 182.426 1.00 9.90   ? 248 GLY A O     1 
ATOM   1745  N  N     . GLU A 1 249 ? 219.796 209.479 183.245 1.00 9.27   ? 249 GLU A N     1 
ATOM   1746  C  CA    . GLU A 1 249 ? 219.118 208.804 184.340 1.00 10.13  ? 249 GLU A CA    1 
ATOM   1747  C  C     . GLU A 1 249 ? 219.774 209.183 185.663 1.00 9.68   ? 249 GLU A C     1 
ATOM   1748  O  O     . GLU A 1 249 ? 220.958 209.468 185.712 1.00 9.39   ? 249 GLU A O     1 
ATOM   1749  C  CB    . GLU A 1 249 ? 219.140 207.290 184.100 1.00 11.76  ? 249 GLU A CB    1 
ATOM   1750  C  CG    . GLU A 1 249 ? 218.868 206.399 185.315 1.00 14.01  ? 249 GLU A CG    1 
ATOM   1751  C  CD    . GLU A 1 249 ? 217.464 206.469 185.896 1.00 16.43  ? 249 GLU A CD    1 
ATOM   1752  O  OE1   . GLU A 1 249 ? 216.675 207.385 185.543 1.00 18.31  ? 249 GLU A OE1   1 
ATOM   1753  O  OE2   . GLU A 1 249 ? 217.172 205.586 186.741 1.00 17.06  ? 249 GLU A OE2   1 
ATOM   1754  N  N     . VAL A 1 250 ? 218.973 209.162 186.726 1.00 9.54   ? 250 VAL A N     1 
ATOM   1755  C  CA    . VAL A 1 250 ? 219.454 209.348 188.081 1.00 9.58   ? 250 VAL A CA    1 
ATOM   1756  C  C     . VAL A 1 250 ? 219.401 208.007 188.791 1.00 9.03   ? 250 VAL A C     1 
ATOM   1757  O  O     . VAL A 1 250 ? 218.352 207.372 188.825 1.00 9.73   ? 250 VAL A O     1 
ATOM   1758  C  CB    . VAL A 1 250 ? 218.601 210.387 188.831 1.00 10.26  ? 250 VAL A CB    1 
ATOM   1759  C  CG1   . VAL A 1 250 ? 219.079 210.556 190.263 1.00 10.36  ? 250 VAL A CG1   1 
ATOM   1760  C  CG2   . VAL A 1 250 ? 218.600 211.724 188.113 1.00 11.03  ? 250 VAL A CG2   1 
ATOM   1761  N  N     . ILE A 1 251 ? 220.532 207.583 189.351 1.00 8.51   ? 251 ILE A N     1 
ATOM   1762  C  CA    . ILE A 1 251 ? 220.604 206.338 190.094 1.00 8.40   ? 251 ILE A CA    1 
ATOM   1763  C  C     . ILE A 1 251 ? 220.757 206.660 191.575 1.00 8.57   ? 251 ILE A C     1 
ATOM   1764  O  O     . ILE A 1 251 ? 221.743 207.274 191.977 1.00 8.87   ? 251 ILE A O     1 
ATOM   1765  C  CB    . ILE A 1 251 ? 221.764 205.460 189.608 1.00 8.14   ? 251 ILE A CB    1 
ATOM   1766  C  CG1   . ILE A 1 251 ? 221.586 205.089 188.135 1.00 8.41   ? 251 ILE A CG1   1 
ATOM   1767  C  CG2   . ILE A 1 251 ? 221.912 204.222 190.492 1.00 7.82   ? 251 ILE A CG2   1 
ATOM   1768  C  CD1   . ILE A 1 251 ? 222.771 204.374 187.535 1.00 8.80   ? 251 ILE A CD1   1 
ATOM   1769  N  N     . ARG A 1 252 ? 219.789 206.219 192.374 1.00 9.09   ? 252 ARG A N     1 
ATOM   1770  C  CA    . ARG A 1 252 ? 219.868 206.352 193.816 1.00 9.65   ? 252 ARG A CA    1 
ATOM   1771  C  C     . ARG A 1 252 ? 220.799 205.285 194.376 1.00 9.44   ? 252 ARG A C     1 
ATOM   1772  O  O     . ARG A 1 252 ? 220.599 204.097 194.154 1.00 10.13  ? 252 ARG A O     1 
ATOM   1773  C  CB    . ARG A 1 252 ? 218.483 206.229 194.448 1.00 11.04  ? 252 ARG A CB    1 
ATOM   1774  C  CG    . ARG A 1 252 ? 217.520 207.345 194.081 1.00 12.73  ? 252 ARG A CG    1 
ATOM   1775  C  CD    . ARG A 1 252 ? 216.168 207.076 194.715 1.00 14.40  ? 252 ARG A CD    1 
ATOM   1776  N  NE    . ARG A 1 252 ? 216.246 207.133 196.179 1.00 15.45  ? 252 ARG A NE    1 
ATOM   1777  C  CZ    . ARG A 1 252 ? 215.446 207.857 196.963 1.00 16.09  ? 252 ARG A CZ    1 
ATOM   1778  N  NH1   . ARG A 1 252 ? 214.428 208.531 196.452 1.00 16.25  ? 252 ARG A NH1   1 
ATOM   1779  N  NH2   . ARG A 1 252 ? 215.657 207.870 198.265 1.00 15.93  ? 252 ARG A NH2   1 
ATOM   1780  N  N     . LEU A 1 253 ? 221.816 205.729 195.109 1.00 9.20   ? 253 LEU A N     1 
ATOM   1781  C  CA    . LEU A 1 253 ? 222.757 204.841 195.772 1.00 8.95   ? 253 LEU A CA    1 
ATOM   1782  C  C     . LEU A 1 253 ? 222.640 205.101 197.268 1.00 9.02   ? 253 LEU A C     1 
ATOM   1783  O  O     . LEU A 1 253 ? 223.365 205.937 197.809 1.00 9.08   ? 253 LEU A O     1 
ATOM   1784  C  CB    . LEU A 1 253 ? 224.165 205.116 195.241 1.00 8.66   ? 253 LEU A CB    1 
ATOM   1785  C  CG    . LEU A 1 253 ? 225.296 204.226 195.766 1.00 8.90   ? 253 LEU A CG    1 
ATOM   1786  C  CD1   . LEU A 1 253 ? 225.092 202.753 195.387 1.00 8.87   ? 253 LEU A CD1   1 
ATOM   1787  C  CD2   . LEU A 1 253 ? 226.617 204.728 195.225 1.00 8.87   ? 253 LEU A CD2   1 
ATOM   1788  N  N     . ASP A 1 254 ? 221.696 204.404 197.916 1.00 9.22   ? 254 ASP A N     1 
ATOM   1789  C  CA    . ASP A 1 254 ? 221.284 204.806 199.251 1.00 9.44   ? 254 ASP A CA    1 
ATOM   1790  C  C     . ASP A 1 254 ? 220.944 203.647 200.183 1.00 9.02   ? 254 ASP A C     1 
ATOM   1791  O  O     . ASP A 1 254 ? 220.484 203.895 201.297 1.00 8.93   ? 254 ASP A O     1 
ATOM   1792  C  CB    . ASP A 1 254 ? 220.084 205.734 199.165 1.00 10.22  ? 254 ASP A CB    1 
ATOM   1793  C  CG    . ASP A 1 254 ? 218.915 205.169 198.375 1.00 11.03  ? 254 ASP A CG    1 
ATOM   1794  O  OD1   . ASP A 1 254 ? 218.990 203.963 198.006 1.00 11.64  ? 254 ASP A OD1   1 
ATOM   1795  O  OD2   . ASP A 1 254 ? 217.952 205.919 198.124 1.00 12.46  ? 254 ASP A OD2   1 
ATOM   1796  N  N     . GLY A 1 255 ? 221.157 202.395 199.769 1.00 8.81   ? 255 GLY A N     1 
ATOM   1797  C  CA    . GLY A 1 255 ? 220.772 201.259 200.594 1.00 8.73   ? 255 GLY A CA    1 
ATOM   1798  C  C     . GLY A 1 255 ? 219.270 201.213 200.900 1.00 8.55   ? 255 GLY A C     1 
ATOM   1799  O  O     . GLY A 1 255 ? 218.893 200.695 201.932 1.00 8.93   ? 255 GLY A O     1 
ATOM   1800  N  N     . ALA A 1 256 ? 218.434 201.760 200.014 1.00 9.05   ? 256 ALA A N     1 
ATOM   1801  C  CA    . ALA A 1 256 ? 216.981 201.758 200.136 1.00 9.86   ? 256 ALA A CA    1 
ATOM   1802  C  C     . ALA A 1 256 ? 216.462 202.662 201.247 1.00 10.76  ? 256 ALA A C     1 
ATOM   1803  O  O     . ALA A 1 256 ? 215.340 202.476 201.697 1.00 12.14  ? 256 ALA A O     1 
ATOM   1804  C  CB    . ALA A 1 256 ? 216.436 200.352 200.321 1.00 9.35   ? 256 ALA A CB    1 
ATOM   1805  N  N     . ILE A 1 257 ? 217.227 203.659 201.685 1.00 11.84  ? 257 ILE A N     1 
ATOM   1806  C  CA    . ILE A 1 257 ? 216.746 204.572 202.712 1.00 12.69  ? 257 ILE A CA    1 
ATOM   1807  C  C     . ILE A 1 257 ? 215.787 205.590 202.094 1.00 12.93  ? 257 ILE A C     1 
ATOM   1808  O  O     . ILE A 1 257 ? 215.910 205.947 200.931 1.00 13.43  ? 257 ILE A O     1 
ATOM   1809  C  CB    . ILE A 1 257 ? 217.908 205.275 203.432 1.00 13.44  ? 257 ILE A CB    1 
ATOM   1810  C  CG1   . ILE A 1 257 ? 217.425 205.903 204.745 1.00 14.70  ? 257 ILE A CG1   1 
ATOM   1811  C  CG2   . ILE A 1 257 ? 218.565 206.321 202.526 1.00 12.89  ? 257 ILE A CG2   1 
ATOM   1812  C  CD1   . ILE A 1 257 ? 218.526 206.226 205.729 1.00 15.64  ? 257 ILE A CD1   1 
ATOM   1813  N  N     . ARG A 1 258 ? 214.811 206.017 202.898 1.00 13.26  ? 258 ARG A N     1 
ATOM   1814  C  CA    . ARG A 1 258 ? 213.942 207.135 202.584 1.00 14.52  ? 258 ARG A CA    1 
ATOM   1815  C  C     . ARG A 1 258 ? 213.942 208.074 203.788 1.00 14.81  ? 258 ARG A C     1 
ATOM   1816  O  O     . ARG A 1 258 ? 213.579 207.679 204.890 1.00 16.10  ? 258 ARG A O     1 
ATOM   1817  C  CB    . ARG A 1 258 ? 212.525 206.654 202.268 1.00 14.33  ? 258 ARG A CB    1 
ATOM   1818  C  CG    . ARG A 1 258 ? 212.436 205.762 201.036 1.00 14.68  ? 258 ARG A CG    1 
ATOM   1819  C  CD    . ARG A 1 258 ? 212.863 206.489 199.772 1.00 14.82  ? 258 ARG A CD    1 
ATOM   1820  N  NE    . ARG A 1 258 ? 212.709 205.628 198.599 1.00 14.42  ? 258 ARG A NE    1 
ATOM   1821  C  CZ    . ARG A 1 258 ? 213.646 204.840 198.090 1.00 15.25  ? 258 ARG A CZ    1 
ATOM   1822  N  NH1   . ARG A 1 258 ? 214.833 204.721 198.667 1.00 15.61  ? 258 ARG A NH1   1 
ATOM   1823  N  NH2   . ARG A 1 258 ? 213.397 204.172 196.974 1.00 16.32  ? 258 ARG A NH2   1 
ATOM   1824  N  N     . MET A 1 259 ? 214.410 209.302 203.576 1.00 15.39  ? 259 MET A N     1 
ATOM   1825  C  CA    . MET A 1 259 ? 214.674 210.213 204.676 1.00 16.65  ? 259 MET A CA    1 
ATOM   1826  C  C     . MET A 1 259 ? 213.372 210.811 205.199 1.00 16.86  ? 259 MET A C     1 
ATOM   1827  O  O     . MET A 1 259 ? 212.539 211.298 204.450 1.00 16.75  ? 259 MET A O     1 
ATOM   1828  C  CB    . MET A 1 259 ? 215.626 211.323 204.228 1.00 17.68  ? 259 MET A CB    1 
ATOM   1829  C  CG    . MET A 1 259 ? 216.943 210.816 203.660 1.00 18.85  ? 259 MET A CG    1 
ATOM   1830  S  SD    . MET A 1 259 ? 217.915 209.943 204.896 1.00 21.42  ? 259 MET A SD    1 
ATOM   1831  C  CE    . MET A 1 259 ? 218.457 211.270 205.976 1.00 21.90  ? 259 MET A CE    1 
ATOM   1832  N  N     . GLN A 1 260 ? 213.213 210.766 206.523 1.00 17.99  ? 260 GLN A N     1 
ATOM   1833  C  CA    . GLN A 1 260 ? 212.079 211.345 207.224 1.00 18.99  ? 260 GLN A CA    1 
ATOM   1834  C  C     . GLN A 1 260 ? 212.387 212.793 207.595 1.00 19.68  ? 260 GLN A C     1 
ATOM   1835  O  O     . GLN A 1 260 ? 213.538 213.215 207.520 1.00 20.47  ? 260 GLN A O     1 
ATOM   1836  C  CB    . GLN A 1 260 ? 211.795 210.508 208.472 1.00 20.30  ? 260 GLN A CB    1 
ATOM   1837  C  CG    . GLN A 1 260 ? 211.234 209.125 208.149 1.00 22.57  ? 260 GLN A CG    1 
ATOM   1838  C  CD    . GLN A 1 260 ? 210.061 209.204 207.198 1.00 24.37  ? 260 GLN A CD    1 
ATOM   1839  O  OE1   . GLN A 1 260 ? 210.081 208.668 206.083 1.00 26.78  ? 260 GLN A OE1   1 
ATOM   1840  N  NE2   . GLN A 1 260 ? 209.004 209.867 207.636 1.00 25.40  ? 260 GLN A NE2   1 
ATOM   1841  N  N     . PRO A 1 261 ? 211.384 213.598 208.007 1.00 20.97  ? 261 PRO A N     1 
ATOM   1842  C  CA    . PRO A 1 261 ? 211.648 214.975 208.429 1.00 23.89  ? 261 PRO A CA    1 
ATOM   1843  C  C     . PRO A 1 261 ? 212.736 215.111 209.501 1.00 29.37  ? 261 PRO A C     1 
ATOM   1844  O  O     . PRO A 1 261 ? 212.715 214.289 210.458 1.00 32.90  ? 261 PRO A O     1 
ATOM   1845  C  CB    . PRO A 1 261 ? 210.307 215.500 208.940 1.00 22.84  ? 261 PRO A CB    1 
ATOM   1846  C  CG    . PRO A 1 261 ? 209.270 214.519 208.454 1.00 22.02  ? 261 PRO A CG    1 
ATOM   1847  C  CD    . PRO A 1 261 ? 209.946 213.277 207.936 1.00 21.39  ? 261 PRO A CD    1 
ATOM   1848  O  OXT   . PRO A 1 261 ? 213.593 216.022 209.340 1.00 27.49  ? 261 PRO A OXT   1 
ATOM   1849  N  N     . SER B 1 7   ? 186.975 227.815 201.640 1.00 35.40  ? 7   SER B N     1 
ATOM   1850  C  CA    . SER B 1 7   ? 186.687 228.913 200.676 1.00 33.51  ? 7   SER B CA    1 
ATOM   1851  C  C     . SER B 1 7   ? 187.801 229.959 200.716 1.00 29.24  ? 7   SER B C     1 
ATOM   1852  O  O     . SER B 1 7   ? 188.401 230.191 201.758 1.00 29.83  ? 7   SER B O     1 
ATOM   1853  C  CB    . SER B 1 7   ? 185.344 229.538 200.955 1.00 35.95  ? 7   SER B CB    1 
ATOM   1854  O  OG    . SER B 1 7   ? 185.357 230.262 202.177 1.00 38.89  ? 7   SER B OG    1 
ATOM   1855  N  N     . VAL B 1 8   ? 188.027 230.625 199.583 1.00 28.27  ? 8   VAL B N     1 
ATOM   1856  C  CA    . VAL B 1 8   ? 189.065 231.637 199.482 1.00 26.17  ? 8   VAL B CA    1 
ATOM   1857  C  C     . VAL B 1 8   ? 188.522 233.030 199.787 1.00 25.27  ? 8   VAL B C     1 
ATOM   1858  O  O     . VAL B 1 8   ? 189.274 233.997 199.730 1.00 26.04  ? 8   VAL B O     1 
ATOM   1859  C  CB    . VAL B 1 8   ? 189.737 231.633 198.103 1.00 24.34  ? 8   VAL B CB    1 
ATOM   1860  C  CG1   . VAL B 1 8   ? 190.245 230.247 197.734 1.00 24.24  ? 8   VAL B CG1   1 
ATOM   1861  C  CG2   . VAL B 1 8   ? 188.814 232.168 197.031 1.00 23.15  ? 8   VAL B CG2   1 
ATOM   1862  N  N     . LYS B 1 9   ? 187.234 233.146 200.105 1.00 27.10  ? 9   LYS B N     1 
ATOM   1863  C  CA    . LYS B 1 9   ? 186.660 234.446 200.420 1.00 29.00  ? 9   LYS B CA    1 
ATOM   1864  C  C     . LYS B 1 9   ? 187.314 235.016 201.677 1.00 25.51  ? 9   LYS B C     1 
ATOM   1865  O  O     . LYS B 1 9   ? 187.420 234.338 202.696 1.00 24.43  ? 9   LYS B O     1 
ATOM   1866  C  CB    . LYS B 1 9   ? 185.147 234.339 200.609 1.00 33.97  ? 9   LYS B CB    1 
ATOM   1867  C  CG    . LYS B 1 9   ? 184.475 235.670 200.847 1.00 40.00  ? 9   LYS B CG    1 
ATOM   1868  C  CD    . LYS B 1 9   ? 182.965 235.548 200.980 1.00 46.40  ? 9   LYS B CD    1 
ATOM   1869  C  CE    . LYS B 1 9   ? 182.358 236.852 201.372 1.00 52.08  ? 9   LYS B CE    1 
ATOM   1870  N  NZ    . LYS B 1 9   ? 182.510 237.885 200.338 1.00 54.98  ? 9   LYS B NZ    1 
ATOM   1871  N  N     . GLY B 1 10  ? 187.759 236.273 201.584 1.00 23.25  ? 10  GLY B N     1 
ATOM   1872  C  CA    . GLY B 1 10  ? 188.389 236.949 202.704 1.00 21.93  ? 10  GLY B CA    1 
ATOM   1873  C  C     . GLY B 1 10  ? 189.891 236.687 202.819 1.00 20.80  ? 10  GLY B C     1 
ATOM   1874  O  O     . GLY B 1 10  ? 190.555 237.354 203.605 1.00 21.39  ? 10  GLY B O     1 
ATOM   1875  N  N     . LEU B 1 11  ? 190.432 235.715 202.067 1.00 18.43  ? 11  LEU B N     1 
ATOM   1876  C  CA    . LEU B 1 11  ? 191.857 235.433 202.125 1.00 16.98  ? 11  LEU B CA    1 
ATOM   1877  C  C     . LEU B 1 11  ? 192.648 236.515 201.397 1.00 15.78  ? 11  LEU B C     1 
ATOM   1878  O  O     . LEU B 1 11  ? 192.152 237.140 200.467 1.00 17.23  ? 11  LEU B O     1 
ATOM   1879  C  CB    . LEU B 1 11  ? 192.169 234.064 201.522 1.00 16.92  ? 11  LEU B CB    1 
ATOM   1880  C  CG    . LEU B 1 11  ? 191.617 232.848 202.267 1.00 17.72  ? 11  LEU B CG    1 
ATOM   1881  C  CD1   . LEU B 1 11  ? 192.132 231.580 201.589 1.00 17.82  ? 11  LEU B CD1   1 
ATOM   1882  C  CD2   . LEU B 1 11  ? 192.009 232.859 203.729 1.00 17.55  ? 11  LEU B CD2   1 
ATOM   1883  N  N     . VAL B 1 12  ? 193.893 236.714 201.832 1.00 14.26  ? 12  VAL B N     1 
ATOM   1884  C  CA    . VAL B 1 12  ? 194.795 237.655 201.195 1.00 13.71  ? 12  VAL B CA    1 
ATOM   1885  C  C     . VAL B 1 12  ? 195.913 236.865 200.528 1.00 12.98  ? 12  VAL B C     1 
ATOM   1886  O  O     . VAL B 1 12  ? 196.615 236.104 201.192 1.00 13.53  ? 12  VAL B O     1 
ATOM   1887  C  CB    . VAL B 1 12  ? 195.372 238.668 202.204 1.00 14.55  ? 12  VAL B CB    1 
ATOM   1888  C  CG1   . VAL B 1 12  ? 196.281 239.668 201.504 1.00 14.42  ? 12  VAL B CG1   1 
ATOM   1889  C  CG2   . VAL B 1 12  ? 194.256 239.372 202.969 1.00 15.20  ? 12  VAL B CG2   1 
ATOM   1890  N  N     . ALA B 1 13  ? 196.064 237.058 199.218 1.00 12.23  ? 13  ALA B N     1 
ATOM   1891  C  CA    . ALA B 1 13  ? 197.049 236.342 198.428 1.00 12.32  ? 13  ALA B CA    1 
ATOM   1892  C  C     . ALA B 1 13  ? 198.083 237.315 197.888 1.00 12.40  ? 13  ALA B C     1 
ATOM   1893  O  O     . ALA B 1 13  ? 197.734 238.348 197.328 1.00 12.78  ? 13  ALA B O     1 
ATOM   1894  C  CB    . ALA B 1 13  ? 196.375 235.587 197.290 1.00 12.02  ? 13  ALA B CB    1 
ATOM   1895  N  N     . VAL B 1 14  ? 199.357 236.957 198.052 1.00 12.41  ? 14  VAL B N     1 
ATOM   1896  C  CA    . VAL B 1 14  ? 200.450 237.642 197.391 1.00 12.46  ? 14  VAL B CA    1 
ATOM   1897  C  C     . VAL B 1 14  ? 200.858 236.817 196.181 1.00 11.70  ? 14  VAL B C     1 
ATOM   1898  O  O     . VAL B 1 14  ? 201.253 235.672 196.327 1.00 11.37  ? 14  VAL B O     1 
ATOM   1899  C  CB    . VAL B 1 14  ? 201.631 237.862 198.349 1.00 13.11  ? 14  VAL B CB    1 
ATOM   1900  C  CG1   . VAL B 1 14  ? 202.837 238.434 197.621 1.00 13.29  ? 14  VAL B CG1   1 
ATOM   1901  C  CG2   . VAL B 1 14  ? 201.218 238.780 199.496 1.00 14.55  ? 14  VAL B CG2   1 
ATOM   1902  N  N     . ILE B 1 15  ? 200.753 237.412 194.995 1.00 11.59  ? 15  ILE B N     1 
ATOM   1903  C  CA    . ILE B 1 15  ? 200.987 236.710 193.749 1.00 11.84  ? 15  ILE B CA    1 
ATOM   1904  C  C     . ILE B 1 15  ? 202.168 237.349 193.036 1.00 11.71  ? 15  ILE B C     1 
ATOM   1905  O  O     . ILE B 1 15  ? 202.055 238.464 192.547 1.00 11.98  ? 15  ILE B O     1 
ATOM   1906  C  CB    . ILE B 1 15  ? 199.726 236.692 192.872 1.00 11.93  ? 15  ILE B CB    1 
ATOM   1907  C  CG1   . ILE B 1 15  ? 198.559 236.054 193.628 1.00 12.01  ? 15  ILE B CG1   1 
ATOM   1908  C  CG2   . ILE B 1 15  ? 200.003 235.959 191.570 1.00 11.92  ? 15  ILE B CG2   1 
ATOM   1909  C  CD1   . ILE B 1 15  ? 197.206 236.352 193.032 1.00 12.31  ? 15  ILE B CD1   1 
ATOM   1910  N  N     . THR B 1 16  ? 203.292 236.643 192.975 1.00 11.59  ? 16  THR B N     1 
ATOM   1911  C  CA    . THR B 1 16  ? 204.470 237.163 192.295 1.00 11.69  ? 16  THR B CA    1 
ATOM   1912  C  C     . THR B 1 16  ? 204.301 236.966 190.798 1.00 13.18  ? 16  THR B C     1 
ATOM   1913  O  O     . THR B 1 16  ? 203.756 235.959 190.346 1.00 13.62  ? 16  THR B O     1 
ATOM   1914  C  CB    . THR B 1 16  ? 205.754 236.494 192.768 1.00 12.08  ? 16  THR B CB    1 
ATOM   1915  O  OG1   . THR B 1 16  ? 205.885 235.229 192.122 1.00 12.57  ? 16  THR B OG1   1 
ATOM   1916  C  CG2   . THR B 1 16  ? 205.788 236.378 194.280 1.00 12.12  ? 16  THR B CG2   1 
ATOM   1917  N  N     . GLY B 1 17  ? 204.766 237.949 190.022 1.00 13.98  ? 17  GLY B N     1 
ATOM   1918  C  CA    . GLY B 1 17  ? 204.534 237.932 188.595 1.00 14.69  ? 17  GLY B CA    1 
ATOM   1919  C  C     . GLY B 1 17  ? 203.040 238.057 188.295 1.00 15.13  ? 17  GLY B C     1 
ATOM   1920  O  O     . GLY B 1 17  ? 202.567 237.499 187.320 1.00 15.59  ? 17  GLY B O     1 
ATOM   1921  N  N     . GLY B 1 18  ? 202.308 238.806 189.125 1.00 15.77  ? 18  GLY B N     1 
ATOM   1922  C  CA    . GLY B 1 18  ? 200.855 238.875 189.045 1.00 17.13  ? 18  GLY B CA    1 
ATOM   1923  C  C     . GLY B 1 18  ? 200.337 239.865 188.006 1.00 17.18  ? 18  GLY B C     1 
ATOM   1924  O  O     . GLY B 1 18  ? 199.132 239.995 187.867 1.00 17.97  ? 18  GLY B O     1 
ATOM   1925  N  N     . ALA B 1 19  ? 201.226 240.549 187.281 1.00 18.53  ? 19  ALA B N     1 
ATOM   1926  C  CA    . ALA B 1 19  ? 200.802 241.518 186.281 1.00 19.73  ? 19  ALA B CA    1 
ATOM   1927  C  C     . ALA B 1 19  ? 200.474 240.861 184.939 1.00 20.53  ? 19  ALA B C     1 
ATOM   1928  O  O     . ALA B 1 19  ? 199.920 241.526 184.069 1.00 23.63  ? 19  ALA B O     1 
ATOM   1929  C  CB    . ALA B 1 19  ? 201.868 242.576 186.099 1.00 20.77  ? 19  ALA B CB    1 
ATOM   1930  N  N     . SER B 1 20  ? 200.831 239.589 184.744 1.00 20.30  ? 20  SER B N     1 
ATOM   1931  C  CA    . SER B 1 20  ? 200.620 238.936 183.465 1.00 21.45  ? 20  SER B CA    1 
ATOM   1932  C  C     . SER B 1 20  ? 200.594 237.422 183.634 1.00 19.86  ? 20  SER B C     1 
ATOM   1933  O  O     . SER B 1 20  ? 200.978 236.905 184.675 1.00 21.87  ? 20  SER B O     1 
ATOM   1934  C  CB    . SER B 1 20  ? 201.680 239.343 182.473 1.00 22.56  ? 20  SER B CB    1 
ATOM   1935  O  OG    . SER B 1 20  ? 202.926 238.721 182.753 1.00 23.62  ? 20  SER B OG    1 
ATOM   1936  N  N     . GLY B 1 21  ? 200.164 236.729 182.578 1.00 19.33  ? 21  GLY B N     1 
ATOM   1937  C  CA    . GLY B 1 21  ? 200.289 235.285 182.482 1.00 17.15  ? 21  GLY B CA    1 
ATOM   1938  C  C     . GLY B 1 21  ? 199.564 234.552 183.608 1.00 15.07  ? 21  GLY B C     1 
ATOM   1939  O  O     . GLY B 1 21  ? 198.433 234.884 183.949 1.00 14.48  ? 21  GLY B O     1 
ATOM   1940  N  N     . LEU B 1 22  ? 200.227 233.534 184.169 1.00 14.53  ? 22  LEU B N     1 
ATOM   1941  C  CA    . LEU B 1 22  ? 199.608 232.683 185.169 1.00 13.77  ? 22  LEU B CA    1 
ATOM   1942  C  C     . LEU B 1 22  ? 199.279 233.478 186.429 1.00 13.31  ? 22  LEU B C     1 
ATOM   1943  O  O     . LEU B 1 22  ? 198.233 233.278 187.035 1.00 12.50  ? 22  LEU B O     1 
ATOM   1944  C  CB    . LEU B 1 22  ? 200.510 231.494 185.483 1.00 14.64  ? 22  LEU B CB    1 
ATOM   1945  C  CG    . LEU B 1 22  ? 200.853 230.595 184.294 1.00 14.97  ? 22  LEU B CG    1 
ATOM   1946  C  CD1   . LEU B 1 22  ? 201.677 229.402 184.744 1.00 15.70  ? 22  LEU B CD1   1 
ATOM   1947  C  CD2   . LEU B 1 22  ? 199.621 230.140 183.540 1.00 16.04  ? 22  LEU B CD2   1 
ATOM   1948  N  N     . GLY B 1 23  ? 200.184 234.360 186.838 1.00 12.91  ? 23  GLY B N     1 
ATOM   1949  C  CA    . GLY B 1 23  ? 199.980 235.160 188.029 1.00 12.27  ? 23  GLY B CA    1 
ATOM   1950  C  C     . GLY B 1 23  ? 198.749 236.059 187.918 1.00 12.37  ? 23  GLY B C     1 
ATOM   1951  O  O     . GLY B 1 23  ? 197.967 236.161 188.858 1.00 11.62  ? 23  GLY B O     1 
ATOM   1952  N  N     . LEU B 1 24  ? 198.565 236.696 186.762 1.00 13.30  ? 24  LEU B N     1 
ATOM   1953  C  CA    . LEU B 1 24  ? 197.418 237.566 186.563 1.00 13.31  ? 24  LEU B CA    1 
ATOM   1954  C  C     . LEU B 1 24  ? 196.118 236.769 186.588 1.00 12.97  ? 24  LEU B C     1 
ATOM   1955  O  O     . LEU B 1 24  ? 195.156 237.185 187.232 1.00 13.61  ? 24  LEU B O     1 
ATOM   1956  C  CB    . LEU B 1 24  ? 197.556 238.336 185.257 1.00 14.86  ? 24  LEU B CB    1 
ATOM   1957  C  CG    . LEU B 1 24  ? 196.388 239.259 184.903 1.00 15.79  ? 24  LEU B CG    1 
ATOM   1958  C  CD1   . LEU B 1 24  ? 196.126 240.253 185.994 1.00 16.06  ? 24  LEU B CD1   1 
ATOM   1959  C  CD2   . LEU B 1 24  ? 196.652 239.963 183.582 1.00 16.46  ? 24  LEU B CD2   1 
ATOM   1960  N  N     . ALA B 1 25  ? 196.088 235.625 185.898 1.00 12.95  ? 25  ALA B N     1 
ATOM   1961  C  CA    . ALA B 1 25  ? 194.893 234.795 185.873 1.00 12.42  ? 25  ALA B CA    1 
ATOM   1962  C  C     . ALA B 1 25  ? 194.539 234.336 187.286 1.00 11.82  ? 25  ALA B C     1 
ATOM   1963  O  O     . ALA B 1 25  ? 193.370 234.249 187.639 1.00 12.05  ? 25  ALA B O     1 
ATOM   1964  C  CB    . ALA B 1 25  ? 195.078 233.617 184.935 1.00 12.54  ? 25  ALA B CB    1 
ATOM   1965  N  N     . THR B 1 26  ? 195.553 234.013 188.092 1.00 11.26  ? 26  THR B N     1 
ATOM   1966  C  CA    . THR B 1 26  ? 195.328 233.615 189.469 1.00 11.33  ? 26  THR B CA    1 
ATOM   1967  C  C     . THR B 1 26  ? 194.699 234.771 190.243 1.00 12.03  ? 26  THR B C     1 
ATOM   1968  O  O     . THR B 1 26  ? 193.798 234.554 191.047 1.00 11.92  ? 26  THR B O     1 
ATOM   1969  C  CB    . THR B 1 26  ? 196.635 233.164 190.118 1.00 11.29  ? 26  THR B CB    1 
ATOM   1970  O  OG1   . THR B 1 26  ? 197.175 232.096 189.348 1.00 10.84  ? 26  THR B OG1   1 
ATOM   1971  C  CG2   . THR B 1 26  ? 196.441 232.742 191.560 1.00 11.41  ? 26  THR B CG2   1 
ATOM   1972  N  N     . ALA B 1 27  ? 195.192 235.995 190.025 1.00 12.60  ? 27  ALA B N     1 
ATOM   1973  C  CA    . ALA B 1 27  ? 194.653 237.160 190.715 1.00 13.84  ? 27  ALA B CA    1 
ATOM   1974  C  C     . ALA B 1 27  ? 193.196 237.403 190.328 1.00 13.96  ? 27  ALA B C     1 
ATOM   1975  O  O     . ALA B 1 27  ? 192.368 237.665 191.190 1.00 13.95  ? 27  ALA B O     1 
ATOM   1976  C  CB    . ALA B 1 27  ? 195.487 238.383 190.424 1.00 14.49  ? 27  ALA B CB    1 
ATOM   1977  N  N     . GLU B 1 28  ? 192.881 237.303 189.040 1.00 16.55  ? 28  GLU B N     1 
ATOM   1978  C  CA    . GLU B 1 28  ? 191.529 237.563 188.574 1.00 18.12  ? 28  GLU B CA    1 
ATOM   1979  C  C     . GLU B 1 28  ? 190.552 236.559 189.177 1.00 17.28  ? 28  GLU B C     1 
ATOM   1980  O  O     . GLU B 1 28  ? 189.450 236.932 189.574 1.00 17.90  ? 28  GLU B O     1 
ATOM   1981  C  CB    . GLU B 1 28  ? 191.444 237.534 187.049 1.00 21.57  ? 28  GLU B CB    1 
ATOM   1982  C  CG    . GLU B 1 28  ? 192.455 238.455 186.379 1.00 26.01  ? 28  GLU B CG    1 
ATOM   1983  C  CD    . GLU B 1 28  ? 192.460 238.364 184.870 1.00 31.74  ? 28  GLU B CD    1 
ATOM   1984  O  OE1   . GLU B 1 28  ? 192.557 237.235 184.327 1.00 35.59  ? 28  GLU B OE1   1 
ATOM   1985  O  OE2   . GLU B 1 28  ? 192.444 239.451 184.249 1.00 35.38  ? 28  GLU B OE2   1 
ATOM   1986  N  N     . ARG B 1 29  ? 190.940 235.284 189.244 1.00 15.87  ? 29  ARG B N     1 
ATOM   1987  C  CA    . ARG B 1 29  ? 190.055 234.271 189.792 1.00 15.80  ? 29  ARG B CA    1 
ATOM   1988  C  C     . ARG B 1 29  ? 189.843 234.481 191.290 1.00 15.29  ? 29  ARG B C     1 
ATOM   1989  O  O     . ARG B 1 29  ? 188.708 234.483 191.767 1.00 17.18  ? 29  ARG B O     1 
ATOM   1990  C  CB    . ARG B 1 29  ? 190.586 232.858 189.533 1.00 16.32  ? 29  ARG B CB    1 
ATOM   1991  C  CG    . ARG B 1 29  ? 189.527 231.814 189.857 1.00 16.90  ? 29  ARG B CG    1 
ATOM   1992  C  CD    . ARG B 1 29  ? 190.080 230.411 189.766 1.00 18.22  ? 29  ARG B CD    1 
ATOM   1993  N  NE    . ARG B 1 29  ? 189.067 229.437 190.178 1.00 19.05  ? 29  ARG B NE    1 
ATOM   1994  C  CZ    . ARG B 1 29  ? 188.019 229.046 189.472 1.00 20.46  ? 29  ARG B CZ    1 
ATOM   1995  N  NH1   . ARG B 1 29  ? 187.880 229.458 188.227 1.00 21.17  ? 29  ARG B NH1   1 
ATOM   1996  N  NH2   . ARG B 1 29  ? 187.135 228.236 190.018 1.00 21.91  ? 29  ARG B NH2   1 
ATOM   1997  N  N     . LEU B 1 30  ? 190.934 234.663 192.041 1.00 14.85  ? 30  LEU B N     1 
ATOM   1998  C  CA    . LEU B 1 30  ? 190.839 234.776 193.489 1.00 15.21  ? 30  LEU B CA    1 
ATOM   1999  C  C     . LEU B 1 30  ? 190.051 236.029 193.868 1.00 15.73  ? 30  LEU B C     1 
ATOM   2000  O  O     . LEU B 1 30  ? 189.229 235.993 194.778 1.00 15.82  ? 30  LEU B O     1 
ATOM   2001  C  CB    . LEU B 1 30  ? 192.218 234.771 194.138 1.00 15.74  ? 30  LEU B CB    1 
ATOM   2002  C  CG    . LEU B 1 30  ? 193.026 233.479 193.983 1.00 16.37  ? 30  LEU B CG    1 
ATOM   2003  C  CD1   . LEU B 1 30  ? 194.411 233.627 194.578 1.00 16.66  ? 30  LEU B CD1   1 
ATOM   2004  C  CD2   . LEU B 1 30  ? 192.271 232.315 194.583 1.00 17.67  ? 30  LEU B CD2   1 
ATOM   2005  N  N     . VAL B 1 31  ? 190.307 237.146 193.191 1.00 17.03  ? 31  VAL B N     1 
ATOM   2006  C  CA    . VAL B 1 31  ? 189.563 238.369 193.455 1.00 18.33  ? 31  VAL B CA    1 
ATOM   2007  C  C     . VAL B 1 31  ? 188.090 238.170 193.118 1.00 19.38  ? 31  VAL B C     1 
ATOM   2008  O  O     . VAL B 1 31  ? 187.219 238.599 193.865 1.00 21.60  ? 31  VAL B O     1 
ATOM   2009  C  CB    . VAL B 1 31  ? 190.170 239.559 192.692 1.00 18.38  ? 31  VAL B CB    1 
ATOM   2010  C  CG1   . VAL B 1 31  ? 189.221 240.741 192.631 1.00 18.61  ? 31  VAL B CG1   1 
ATOM   2011  C  CG2   . VAL B 1 31  ? 191.499 239.970 193.307 1.00 18.44  ? 31  VAL B CG2   1 
ATOM   2012  N  N     . GLY B 1 32  ? 187.807 237.512 191.993 1.00 20.97  ? 32  GLY B N     1 
ATOM   2013  C  CA    . GLY B 1 32  ? 186.438 237.198 191.605 1.00 20.45  ? 32  GLY B CA    1 
ATOM   2014  C  C     . GLY B 1 32  ? 185.724 236.302 192.617 1.00 20.42  ? 32  GLY B C     1 
ATOM   2015  O  O     . GLY B 1 32  ? 184.500 236.332 192.711 1.00 22.56  ? 32  GLY B O     1 
ATOM   2016  N  N     . GLN B 1 33  ? 186.486 235.492 193.356 1.00 22.03  ? 33  GLN B N     1 
ATOM   2017  C  CA    . GLN B 1 33  ? 185.924 234.598 194.356 1.00 22.17  ? 33  GLN B CA    1 
ATOM   2018  C  C     . GLN B 1 33  ? 185.903 235.231 195.746 1.00 21.35  ? 33  GLN B C     1 
ATOM   2019  O  O     . GLN B 1 33  ? 185.568 234.556 196.710 1.00 23.70  ? 33  GLN B O     1 
ATOM   2020  C  CB    . GLN B 1 33  ? 186.730 233.301 194.401 1.00 24.44  ? 33  GLN B CB    1 
ATOM   2021  C  CG    . GLN B 1 33  ? 186.657 232.475 193.125 1.00 26.25  ? 33  GLN B CG    1 
ATOM   2022  C  CD    . GLN B 1 33  ? 185.408 231.627 193.035 1.00 29.73  ? 33  GLN B CD    1 
ATOM   2023  O  OE1   . GLN B 1 33  ? 184.998 230.941 193.984 1.00 32.03  ? 33  GLN B OE1   1 
ATOM   2024  N  NE2   . GLN B 1 33  ? 184.751 231.707 191.888 1.00 32.45  ? 33  GLN B NE2   1 
ATOM   2025  N  N     . GLY B 1 34  ? 186.258 236.514 195.861 1.00 20.47  ? 34  GLY B N     1 
ATOM   2026  C  CA    . GLY B 1 34  ? 186.114 237.245 197.107 1.00 20.38  ? 34  GLY B CA    1 
ATOM   2027  C  C     . GLY B 1 34  ? 187.418 237.410 197.886 1.00 19.40  ? 34  GLY B C     1 
ATOM   2028  O  O     . GLY B 1 34  ? 187.399 237.946 198.988 1.00 20.99  ? 34  GLY B O     1 
ATOM   2029  N  N     . ALA B 1 35  ? 188.553 236.981 197.326 1.00 18.76  ? 35  ALA B N     1 
ATOM   2030  C  CA    . ALA B 1 35  ? 189.833 237.132 198.002 1.00 18.12  ? 35  ALA B CA    1 
ATOM   2031  C  C     . ALA B 1 35  ? 190.434 238.504 197.700 1.00 17.19  ? 35  ALA B C     1 
ATOM   2032  O  O     . ALA B 1 35  ? 189.981 239.222 196.821 1.00 18.01  ? 35  ALA B O     1 
ATOM   2033  C  CB    . ALA B 1 35  ? 190.778 236.019 197.602 1.00 18.26  ? 35  ALA B CB    1 
ATOM   2034  N  N     . SER B 1 36  ? 191.457 238.858 198.474 1.00 18.32  ? 36  SER B N     1 
ATOM   2035  C  CA    . SER B 1 36  ? 192.275 240.038 198.241 1.00 18.88  ? 36  SER B CA    1 
ATOM   2036  C  C     . SER B 1 36  ? 193.612 239.600 197.645 1.00 17.97  ? 36  SER B C     1 
ATOM   2037  O  O     . SER B 1 36  ? 194.205 238.621 198.106 1.00 18.40  ? 36  SER B O     1 
ATOM   2038  C  CB    . SER B 1 36  ? 192.488 240.803 199.521 1.00 19.16  ? 36  SER B CB    1 
ATOM   2039  O  OG    . SER B 1 36  ? 191.250 241.201 200.080 1.00 20.81  ? 36  SER B OG    1 
ATOM   2040  N  N     . ALA B 1 37  ? 194.082 240.342 196.641 1.00 16.75  ? 37  ALA B N     1 
ATOM   2041  C  CA    . ALA B 1 37  ? 195.302 239.990 195.934 1.00 16.59  ? 37  ALA B CA    1 
ATOM   2042  C  C     . ALA B 1 37  ? 196.280 241.153 195.971 1.00 16.73  ? 37  ALA B C     1 
ATOM   2043  O  O     . ALA B 1 37  ? 195.893 242.314 195.877 1.00 17.91  ? 37  ALA B O     1 
ATOM   2044  C  CB    . ALA B 1 37  ? 195.000 239.598 194.505 1.00 17.04  ? 37  ALA B CB    1 
ATOM   2045  N  N     . VAL B 1 38  ? 197.564 240.813 196.100 1.00 16.26  ? 38  VAL B N     1 
ATOM   2046  C  CA    . VAL B 1 38  ? 198.650 241.759 195.945 1.00 15.90  ? 38  VAL B CA    1 
ATOM   2047  C  C     . VAL B 1 38  ? 199.483 241.314 194.754 1.00 16.09  ? 38  VAL B C     1 
ATOM   2048  O  O     . VAL B 1 38  ? 200.044 240.216 194.752 1.00 16.09  ? 38  VAL B O     1 
ATOM   2049  C  CB    . VAL B 1 38  ? 199.504 241.829 197.217 1.00 16.42  ? 38  VAL B CB    1 
ATOM   2050  C  CG1   . VAL B 1 38  ? 200.692 242.757 197.030 1.00 16.48  ? 38  VAL B CG1   1 
ATOM   2051  C  CG2   . VAL B 1 38  ? 198.661 242.228 198.425 1.00 17.39  ? 38  VAL B CG2   1 
ATOM   2052  N  N     . LEU B 1 39  ? 199.543 242.167 193.729 1.00 16.54  ? 39  LEU B N     1 
ATOM   2053  C  CA    . LEU B 1 39  ? 200.322 241.863 192.543 1.00 17.47  ? 39  LEU B CA    1 
ATOM   2054  C  C     . LEU B 1 39  ? 201.767 242.289 192.784 1.00 18.27  ? 39  LEU B C     1 
ATOM   2055  O  O     . LEU B 1 39  ? 202.087 243.479 192.787 1.00 18.94  ? 39  LEU B O     1 
ATOM   2056  C  CB    . LEU B 1 39  ? 199.736 242.568 191.321 1.00 17.61  ? 39  LEU B CB    1 
ATOM   2057  C  CG    . LEU B 1 39  ? 198.250 242.333 191.055 1.00 17.86  ? 39  LEU B CG    1 
ATOM   2058  C  CD1   . LEU B 1 39  ? 197.873 242.944 189.720 1.00 17.99  ? 39  LEU B CD1   1 
ATOM   2059  C  CD2   . LEU B 1 39  ? 197.901 240.861 191.091 1.00 18.32  ? 39  LEU B CD2   1 
ATOM   2060  N  N     . LEU B 1 40  ? 202.639 241.294 192.970 1.00 18.05  ? 40  LEU B N     1 
ATOM   2061  C  CA    . LEU B 1 40  ? 204.061 241.518 193.155 1.00 18.43  ? 40  LEU B CA    1 
ATOM   2062  C  C     . LEU B 1 40  ? 204.739 241.284 191.809 1.00 18.82  ? 40  LEU B C     1 
ATOM   2063  O  O     . LEU B 1 40  ? 204.845 240.151 191.337 1.00 19.00  ? 40  LEU B O     1 
ATOM   2064  C  CB    . LEU B 1 40  ? 204.569 240.594 194.262 1.00 19.54  ? 40  LEU B CB    1 
ATOM   2065  C  CG    . LEU B 1 40  ? 205.929 240.913 194.890 1.00 20.09  ? 40  LEU B CG    1 
ATOM   2066  C  CD1   . LEU B 1 40  ? 206.028 240.276 196.259 1.00 20.26  ? 40  LEU B CD1   1 
ATOM   2067  C  CD2   . LEU B 1 40  ? 207.089 240.437 194.037 1.00 22.15  ? 40  LEU B CD2   1 
ATOM   2068  N  N     . ASP B 1 41  ? 205.180 242.373 191.180 1.00 18.92  ? 41  ASP B N     1 
ATOM   2069  C  CA    . ASP B 1 41  ? 205.813 242.290 189.877 1.00 20.51  ? 41  ASP B CA    1 
ATOM   2070  C  C     . ASP B 1 41  ? 206.775 243.457 189.714 1.00 19.35  ? 41  ASP B C     1 
ATOM   2071  O  O     . ASP B 1 41  ? 206.800 244.364 190.537 1.00 19.45  ? 41  ASP B O     1 
ATOM   2072  C  CB    . ASP B 1 41  ? 204.785 242.232 188.758 1.00 23.01  ? 41  ASP B CB    1 
ATOM   2073  C  CG    . ASP B 1 41  ? 205.232 241.408 187.560 1.00 25.23  ? 41  ASP B CG    1 
ATOM   2074  O  OD1   . ASP B 1 41  ? 206.432 241.462 187.219 1.00 26.18  ? 41  ASP B OD1   1 
ATOM   2075  O  OD2   . ASP B 1 41  ? 204.371 240.723 186.971 1.00 25.90  ? 41  ASP B OD2   1 
ATOM   2076  N  N     . LEU B 1 42  ? 207.568 243.414 188.647 1.00 20.06  ? 42  LEU B N     1 
ATOM   2077  C  CA    . LEU B 1 42  ? 208.571 244.442 188.405 1.00 22.22  ? 42  LEU B CA    1 
ATOM   2078  C  C     . LEU B 1 42  ? 207.886 245.778 188.143 1.00 22.62  ? 42  LEU B C     1 
ATOM   2079  O  O     . LEU B 1 42  ? 206.743 245.830 187.696 1.00 21.58  ? 42  LEU B O     1 
ATOM   2080  C  CB    . LEU B 1 42  ? 209.459 244.043 187.231 1.00 22.28  ? 42  LEU B CB    1 
ATOM   2081  C  CG    . LEU B 1 42  ? 210.315 242.793 187.439 1.00 22.59  ? 42  LEU B CG    1 
ATOM   2082  C  CD1   . LEU B 1 42  ? 210.952 242.347 186.146 1.00 24.09  ? 42  LEU B CD1   1 
ATOM   2083  C  CD2   . LEU B 1 42  ? 211.383 243.054 188.472 1.00 22.30  ? 42  LEU B CD2   1 
ATOM   2084  N  N     . PRO B 1 43  ? 208.561 246.908 188.445 1.00 25.98  ? 43  PRO B N     1 
ATOM   2085  C  CA    . PRO B 1 43  ? 207.987 248.233 188.209 1.00 28.13  ? 43  PRO B CA    1 
ATOM   2086  C  C     . PRO B 1 43  ? 207.506 248.493 186.789 1.00 30.59  ? 43  PRO B C     1 
ATOM   2087  O  O     . PRO B 1 43  ? 206.543 249.230 186.605 1.00 34.29  ? 43  PRO B O     1 
ATOM   2088  C  CB    . PRO B 1 43  ? 209.130 249.172 188.595 1.00 28.24  ? 43  PRO B CB    1 
ATOM   2089  C  CG    . PRO B 1 43  ? 209.890 248.399 189.626 1.00 27.85  ? 43  PRO B CG    1 
ATOM   2090  C  CD    . PRO B 1 43  ? 209.880 246.981 189.083 1.00 26.80  ? 43  PRO B CD    1 
ATOM   2091  N  N     . ASN B 1 44  ? 208.158 247.892 185.790 1.00 32.63  ? 44  ASN B N     1 
ATOM   2092  C  CA    . ASN B 1 44  ? 207.795 248.143 184.400 1.00 38.82  ? 44  ASN B CA    1 
ATOM   2093  C  C     . ASN B 1 44  ? 206.752 247.152 183.872 1.00 36.17  ? 44  ASN B C     1 
ATOM   2094  O  O     . ASN B 1 44  ? 206.389 247.216 182.704 1.00 39.13  ? 44  ASN B O     1 
ATOM   2095  C  CB    . ASN B 1 44  ? 209.023 248.100 183.494 1.00 43.72  ? 44  ASN B CB    1 
ATOM   2096  C  CG    . ASN B 1 44  ? 209.624 246.716 183.377 1.00 50.98  ? 44  ASN B CG    1 
ATOM   2097  O  OD1   . ASN B 1 44  ? 209.377 245.840 184.212 1.00 52.33  ? 44  ASN B OD1   1 
ATOM   2098  N  ND2   . ASN B 1 44  ? 210.403 246.493 182.330 1.00 55.68  ? 44  ASN B ND2   1 
ATOM   2099  N  N     . SER B 1 45  ? 206.258 246.249 184.723 1.00 34.46  ? 45  SER B N     1 
ATOM   2100  C  CA    . SER B 1 45  ? 205.387 245.164 184.282 1.00 32.27  ? 45  SER B CA    1 
ATOM   2101  C  C     . SER B 1 45  ? 203.976 245.633 183.932 1.00 31.17  ? 45  SER B C     1 
ATOM   2102  O  O     . SER B 1 45  ? 203.212 244.874 183.344 1.00 33.00  ? 45  SER B O     1 
ATOM   2103  C  CB    . SER B 1 45  ? 205.309 244.076 185.323 1.00 32.12  ? 45  SER B CB    1 
ATOM   2104  O  OG    . SER B 1 45  ? 204.805 244.598 186.544 1.00 29.66  ? 45  SER B OG    1 
ATOM   2105  N  N     . GLY B 1 46  ? 203.610 246.855 184.310 1.00 30.00  ? 46  GLY B N     1 
ATOM   2106  C  CA    . GLY B 1 46  ? 202.253 247.322 184.085 1.00 28.04  ? 46  GLY B CA    1 
ATOM   2107  C  C     . GLY B 1 46  ? 201.268 246.771 185.116 1.00 26.48  ? 46  GLY B C     1 
ATOM   2108  O  O     . GLY B 1 46  ? 200.081 246.729 184.846 1.00 26.04  ? 46  GLY B O     1 
ATOM   2109  N  N     . GLY B 1 47  ? 201.757 246.399 186.304 1.00 26.18  ? 47  GLY B N     1 
ATOM   2110  C  CA    . GLY B 1 47  ? 200.905 245.839 187.335 1.00 24.81  ? 47  GLY B CA    1 
ATOM   2111  C  C     . GLY B 1 47  ? 199.925 246.849 187.920 1.00 25.77  ? 47  GLY B C     1 
ATOM   2112  O  O     . GLY B 1 47  ? 198.873 246.459 188.423 1.00 25.60  ? 47  GLY B O     1 
ATOM   2113  N  N     . GLU B 1 48  ? 200.261 248.142 187.869 1.00 28.47  ? 48  GLU B N     1 
ATOM   2114  C  CA    . GLU B 1 48  ? 199.376 249.168 188.396 1.00 30.56  ? 48  GLU B CA    1 
ATOM   2115  C  C     . GLU B 1 48  ? 198.048 249.184 187.635 1.00 27.53  ? 48  GLU B C     1 
ATOM   2116  O  O     . GLU B 1 48  ? 196.986 249.302 188.237 1.00 26.09  ? 48  GLU B O     1 
ATOM   2117  C  CB    . GLU B 1 48  ? 200.057 250.535 188.341 1.00 37.01  ? 48  GLU B CB    1 
ATOM   2118  C  CG    . GLU B 1 48  ? 199.210 251.659 188.930 1.00 42.16  ? 48  GLU B CG    1 
ATOM   2119  C  CD    . GLU B 1 48  ? 198.884 251.496 190.405 1.00 50.81  ? 48  GLU B CD    1 
ATOM   2120  O  OE1   . GLU B 1 48  ? 199.645 250.824 191.143 1.00 53.32  ? 48  GLU B OE1   1 
ATOM   2121  O  OE2   . GLU B 1 48  ? 197.838 252.045 190.812 1.00 55.88  ? 48  GLU B OE2   1 
ATOM   2122  N  N     . ALA B 1 49  ? 198.102 249.070 186.307 1.00 26.45  ? 49  ALA B N     1 
ATOM   2123  C  CA    . ALA B 1 49  ? 196.891 249.047 185.501 1.00 25.63  ? 49  ALA B CA    1 
ATOM   2124  C  C     . ALA B 1 49  ? 196.068 247.789 185.784 1.00 24.69  ? 49  ALA B C     1 
ATOM   2125  O  O     . ALA B 1 49  ? 194.848 247.852 185.876 1.00 23.88  ? 49  ALA B O     1 
ATOM   2126  C  CB    . ALA B 1 49  ? 197.245 249.149 184.039 1.00 26.08  ? 49  ALA B CB    1 
ATOM   2127  N  N     . GLN B 1 50  ? 196.732 246.643 185.947 1.00 23.90  ? 50  GLN B N     1 
ATOM   2128  C  CA    . GLN B 1 50  ? 196.028 245.408 186.249 1.00 23.40  ? 50  GLN B CA    1 
ATOM   2129  C  C     . GLN B 1 50  ? 195.360 245.478 187.616 1.00 22.52  ? 50  GLN B C     1 
ATOM   2130  O  O     . GLN B 1 50  ? 194.219 245.042 187.770 1.00 23.82  ? 50  GLN B O     1 
ATOM   2131  C  CB    . GLN B 1 50  ? 196.975 244.214 186.168 1.00 24.30  ? 50  GLN B CB    1 
ATOM   2132  C  CG    . GLN B 1 50  ? 197.508 243.955 184.762 1.00 26.35  ? 50  GLN B CG    1 
ATOM   2133  C  CD    . GLN B 1 50  ? 196.417 243.869 183.719 1.00 28.90  ? 50  GLN B CD    1 
ATOM   2134  O  OE1   . GLN B 1 50  ? 195.381 243.236 183.940 1.00 30.27  ? 50  GLN B OE1   1 
ATOM   2135  N  NE2   . GLN B 1 50  ? 196.604 244.556 182.604 1.00 31.26  ? 50  GLN B NE2   1 
ATOM   2136  N  N     . ALA B 1 51  ? 196.065 246.022 188.612 1.00 22.41  ? 51  ALA B N     1 
ATOM   2137  C  CA    . ALA B 1 51  ? 195.506 246.137 189.951 1.00 22.89  ? 51  ALA B CA    1 
ATOM   2138  C  C     . ALA B 1 51  ? 194.290 247.058 189.945 1.00 24.38  ? 51  ALA B C     1 
ATOM   2139  O  O     . ALA B 1 51  ? 193.301 246.783 190.616 1.00 25.03  ? 51  ALA B O     1 
ATOM   2140  C  CB    . ALA B 1 51  ? 196.553 246.604 190.943 1.00 22.34  ? 51  ALA B CB    1 
ATOM   2141  N  N     . LYS B 1 52  ? 194.373 248.168 189.208 1.00 26.86  ? 52  LYS B N     1 
ATOM   2142  C  CA    . LYS B 1 52  ? 193.248 249.084 189.088 1.00 29.65  ? 52  LYS B CA    1 
ATOM   2143  C  C     . LYS B 1 52  ? 192.070 248.397 188.403 1.00 28.92  ? 52  LYS B C     1 
ATOM   2144  O  O     . LYS B 1 52  ? 190.924 248.610 188.781 1.00 31.24  ? 52  LYS B O     1 
ATOM   2145  C  CB    . LYS B 1 52  ? 193.669 250.338 188.320 1.00 32.89  ? 52  LYS B CB    1 
ATOM   2146  C  CG    . LYS B 1 52  ? 192.583 251.370 188.135 1.00 39.45  ? 52  LYS B CG    1 
ATOM   2147  C  CD    . LYS B 1 52  ? 193.118 252.609 187.422 1.00 45.26  ? 52  LYS B CD    1 
ATOM   2148  C  CE    . LYS B 1 52  ? 192.050 253.601 187.077 1.00 49.32  ? 52  LYS B CE    1 
ATOM   2149  N  NZ    . LYS B 1 52  ? 191.389 254.119 188.277 1.00 52.10  ? 52  LYS B NZ    1 
ATOM   2150  N  N     . LYS B 1 53  ? 192.348 247.568 187.398 1.00 28.76  ? 53  LYS B N     1 
ATOM   2151  C  CA    . LYS B 1 53  ? 191.296 246.859 186.689 1.00 30.40  ? 53  LYS B CA    1 
ATOM   2152  C  C     . LYS B 1 53  ? 190.579 245.873 187.610 1.00 29.49  ? 53  LYS B C     1 
ATOM   2153  O  O     . LYS B 1 53  ? 189.366 245.709 187.522 1.00 29.40  ? 53  LYS B O     1 
ATOM   2154  C  CB    . LYS B 1 53  ? 191.891 246.142 185.479 1.00 34.60  ? 53  LYS B CB    1 
ATOM   2155  C  CG    . LYS B 1 53  ? 190.885 245.408 184.627 1.00 40.29  ? 53  LYS B CG    1 
ATOM   2156  C  CD    . LYS B 1 53  ? 191.525 244.698 183.442 1.00 45.89  ? 53  LYS B CD    1 
ATOM   2157  C  CE    . LYS B 1 53  ? 192.244 245.632 182.516 1.00 52.11  ? 53  LYS B CE    1 
ATOM   2158  N  NZ    . LYS B 1 53  ? 192.708 244.966 181.295 1.00 56.65  ? 53  LYS B NZ    1 
ATOM   2159  N  N     . LEU B 1 54  ? 191.318 245.227 188.516 1.00 29.07  ? 54  LEU B N     1 
ATOM   2160  C  CA    . LEU B 1 54  ? 190.745 244.186 189.359 1.00 28.01  ? 54  LEU B CA    1 
ATOM   2161  C  C     . LEU B 1 54  ? 189.945 244.757 190.529 1.00 28.36  ? 54  LEU B C     1 
ATOM   2162  O  O     . LEU B 1 54  ? 189.242 244.011 191.205 1.00 30.63  ? 54  LEU B O     1 
ATOM   2163  C  CB    . LEU B 1 54  ? 191.844 243.255 189.859 1.00 29.13  ? 54  LEU B CB    1 
ATOM   2164  C  CG    . LEU B 1 54  ? 192.369 242.265 188.822 1.00 29.46  ? 54  LEU B CG    1 
ATOM   2165  C  CD1   . LEU B 1 54  ? 193.558 241.479 189.329 1.00 30.93  ? 54  LEU B CD1   1 
ATOM   2166  C  CD2   . LEU B 1 54  ? 191.236 241.335 188.438 1.00 31.38  ? 54  LEU B CD2   1 
ATOM   2167  N  N     . GLY B 1 55  ? 190.061 246.063 190.797 1.00 28.67  ? 55  GLY B N     1 
ATOM   2168  C  CA    . GLY B 1 55  ? 189.225 246.726 191.788 1.00 27.52  ? 55  GLY B CA    1 
ATOM   2169  C  C     . GLY B 1 55  ? 189.953 246.979 193.104 1.00 27.54  ? 55  GLY B C     1 
ATOM   2170  O  O     . GLY B 1 55  ? 191.174 246.884 193.185 1.00 30.11  ? 55  GLY B O     1 
ATOM   2171  N  N     . ASN B 1 56  ? 189.169 247.292 194.136 1.00 28.70  ? 56  ASN B N     1 
ATOM   2172  C  CA    . ASN B 1 56  ? 189.703 247.753 195.405 1.00 30.40  ? 56  ASN B CA    1 
ATOM   2173  C  C     . ASN B 1 56  ? 190.361 246.627 196.192 1.00 27.95  ? 56  ASN B C     1 
ATOM   2174  O  O     . ASN B 1 56  ? 191.212 246.888 197.034 1.00 29.90  ? 56  ASN B O     1 
ATOM   2175  C  CB    . ASN B 1 56  ? 188.629 248.405 196.264 1.00 35.57  ? 56  ASN B CB    1 
ATOM   2176  C  CG    . ASN B 1 56  ? 187.974 249.580 195.575 1.00 40.18  ? 56  ASN B CG    1 
ATOM   2177  O  OD1   . ASN B 1 56  ? 188.476 250.075 194.555 1.00 43.27  ? 56  ASN B OD1   1 
ATOM   2178  N  ND2   . ASN B 1 56  ? 186.825 249.991 196.079 1.00 42.36  ? 56  ASN B ND2   1 
ATOM   2179  N  N     . ASN B 1 57  ? 190.003 245.371 195.898 1.00 26.57  ? 57  ASN B N     1 
ATOM   2180  C  CA    . ASN B 1 57  ? 190.570 244.241 196.623 1.00 25.56  ? 57  ASN B CA    1 
ATOM   2181  C  C     . ASN B 1 57  ? 191.874 243.759 195.987 1.00 23.21  ? 57  ASN B C     1 
ATOM   2182  O  O     . ASN B 1 57  ? 192.372 242.694 196.338 1.00 22.88  ? 57  ASN B O     1 
ATOM   2183  C  CB    . ASN B 1 57  ? 189.583 243.085 196.732 1.00 27.72  ? 57  ASN B CB    1 
ATOM   2184  C  CG    . ASN B 1 57  ? 188.395 243.409 197.607 1.00 30.87  ? 57  ASN B CG    1 
ATOM   2185  O  OD1   . ASN B 1 57  ? 188.546 244.004 198.679 1.00 31.31  ? 57  ASN B OD1   1 
ATOM   2186  N  ND2   . ASN B 1 57  ? 187.198 243.083 197.141 1.00 33.71  ? 57  ASN B ND2   1 
ATOM   2187  N  N     . CYS B 1 58  ? 192.443 244.547 195.069 1.00 22.32  ? 58  CYS B N     1 
ATOM   2188  C  CA    . CYS B 1 58  ? 193.723 244.236 194.453 1.00 21.38  ? 58  CYS B CA    1 
ATOM   2189  C  C     . CYS B 1 58  ? 194.617 245.470 194.503 1.00 21.44  ? 58  CYS B C     1 
ATOM   2190  O  O     . CYS B 1 58  ? 194.174 246.574 194.201 1.00 22.70  ? 58  CYS B O     1 
ATOM   2191  C  CB    . CYS B 1 58  ? 193.527 243.777 193.013 1.00 22.22  ? 58  CYS B CB    1 
ATOM   2192  S  SG    . CYS B 1 58  ? 195.017 243.081 192.264 1.00 23.15  ? 58  CYS B SG    1 
ATOM   2193  N  N     . VAL B 1 59  ? 195.886 245.266 194.870 1.00 20.12  ? 59  VAL B N     1 
ATOM   2194  C  CA    . VAL B 1 59  ? 196.878 246.324 194.889 1.00 20.94  ? 59  VAL B CA    1 
ATOM   2195  C  C     . VAL B 1 59  ? 198.132 245.839 194.177 1.00 19.90  ? 59  VAL B C     1 
ATOM   2196  O  O     . VAL B 1 59  ? 198.399 244.635 194.095 1.00 21.15  ? 59  VAL B O     1 
ATOM   2197  C  CB    . VAL B 1 59  ? 197.203 246.728 196.340 1.00 22.92  ? 59  VAL B CB    1 
ATOM   2198  C  CG1   . VAL B 1 59  ? 197.990 245.649 197.065 1.00 24.39  ? 59  VAL B CG1   1 
ATOM   2199  C  CG2   . VAL B 1 59  ? 197.961 248.037 196.407 1.00 25.47  ? 59  VAL B CG2   1 
ATOM   2200  N  N     . PHE B 1 60  ? 198.892 246.794 193.645 1.00 20.11  ? 60  PHE B N     1 
ATOM   2201  C  CA    . PHE B 1 60  ? 200.141 246.506 192.964 1.00 19.93  ? 60  PHE B CA    1 
ATOM   2202  C  C     . PHE B 1 60  ? 201.308 246.825 193.891 1.00 20.25  ? 60  PHE B C     1 
ATOM   2203  O  O     . PHE B 1 60  ? 201.403 247.931 194.408 1.00 21.44  ? 60  PHE B O     1 
ATOM   2204  C  CB    . PHE B 1 60  ? 200.239 247.305 191.668 1.00 20.98  ? 60  PHE B CB    1 
ATOM   2205  C  CG    . PHE B 1 60  ? 201.596 247.200 191.007 1.00 22.87  ? 60  PHE B CG    1 
ATOM   2206  C  CD1   . PHE B 1 60  ? 202.152 245.959 190.712 1.00 23.11  ? 60  PHE B CD1   1 
ATOM   2207  C  CD2   . PHE B 1 60  ? 202.313 248.348 190.693 1.00 23.90  ? 60  PHE B CD2   1 
ATOM   2208  C  CE1   . PHE B 1 60  ? 203.386 245.875 190.096 1.00 23.62  ? 60  PHE B CE1   1 
ATOM   2209  C  CE2   . PHE B 1 60  ? 203.554 248.256 190.090 1.00 23.77  ? 60  PHE B CE2   1 
ATOM   2210  C  CZ    . PHE B 1 60  ? 204.087 247.022 189.791 1.00 23.78  ? 60  PHE B CZ    1 
ATOM   2211  N  N     . ALA B 1 61  ? 202.197 245.845 194.084 1.00 19.26  ? 61  ALA B N     1 
ATOM   2212  C  CA    . ALA B 1 61  ? 203.400 246.026 194.882 1.00 19.40  ? 61  ALA B CA    1 
ATOM   2213  C  C     . ALA B 1 61  ? 204.617 245.828 193.995 1.00 19.81  ? 61  ALA B C     1 
ATOM   2214  O  O     . ALA B 1 61  ? 204.997 244.695 193.712 1.00 20.94  ? 61  ALA B O     1 
ATOM   2215  C  CB    . ALA B 1 61  ? 203.434 245.068 196.048 1.00 19.62  ? 61  ALA B CB    1 
ATOM   2216  N  N     . PRO B 1 62  ? 205.268 246.911 193.521 1.00 21.06  ? 62  PRO B N     1 
ATOM   2217  C  CA    . PRO B 1 62  ? 206.447 246.768 192.669 1.00 21.42  ? 62  PRO B CA    1 
ATOM   2218  C  C     . PRO B 1 62  ? 207.599 246.159 193.459 1.00 21.00  ? 62  PRO B C     1 
ATOM   2219  O  O     . PRO B 1 62  ? 207.974 246.662 194.510 1.00 23.06  ? 62  PRO B O     1 
ATOM   2220  C  CB    . PRO B 1 62  ? 206.743 248.193 192.200 1.00 22.36  ? 62  PRO B CB    1 
ATOM   2221  C  CG    . PRO B 1 62  ? 206.164 249.051 193.298 1.00 22.28  ? 62  PRO B CG    1 
ATOM   2222  C  CD    . PRO B 1 62  ? 204.929 248.317 193.783 1.00 21.85  ? 62  PRO B CD    1 
ATOM   2223  N  N     . ALA B 1 63  ? 208.146 245.059 192.948 1.00 20.35  ? 63  ALA B N     1 
ATOM   2224  C  CA    . ALA B 1 63  ? 209.243 244.386 193.615 1.00 20.26  ? 63  ALA B CA    1 
ATOM   2225  C  C     . ALA B 1 63  ? 209.963 243.478 192.633 1.00 19.97  ? 63  ALA B C     1 
ATOM   2226  O  O     . ALA B 1 63  ? 209.373 242.973 191.692 1.00 20.64  ? 63  ALA B O     1 
ATOM   2227  C  CB    . ALA B 1 63  ? 208.756 243.617 194.820 1.00 20.18  ? 63  ALA B CB    1 
ATOM   2228  N  N     . ASP B 1 64  ? 211.259 243.285 192.891 1.00 21.14  ? 64  ASP B N     1 
ATOM   2229  C  CA    . ASP B 1 64  ? 212.046 242.252 192.248 1.00 20.60  ? 64  ASP B CA    1 
ATOM   2230  C  C     . ASP B 1 64  ? 212.187 241.096 193.231 1.00 18.39  ? 64  ASP B C     1 
ATOM   2231  O  O     . ASP B 1 64  ? 212.706 241.289 194.328 1.00 18.84  ? 64  ASP B O     1 
ATOM   2232  C  CB    . ASP B 1 64  ? 213.393 242.810 191.831 1.00 23.23  ? 64  ASP B CB    1 
ATOM   2233  C  CG    . ASP B 1 64  ? 214.275 241.844 191.056 1.00 27.24  ? 64  ASP B CG    1 
ATOM   2234  O  OD1   . ASP B 1 64  ? 215.252 242.328 190.441 1.00 30.95  ? 64  ASP B OD1   1 
ATOM   2235  O  OD2   . ASP B 1 64  ? 213.988 240.628 191.062 1.00 30.46  ? 64  ASP B OD2   1 
ATOM   2236  N  N     . VAL B 1 65  ? 211.761 239.897 192.818 1.00 16.94  ? 65  VAL B N     1 
ATOM   2237  C  CA    . VAL B 1 65  ? 211.735 238.755 193.718 1.00 16.12  ? 65  VAL B CA    1 
ATOM   2238  C  C     . VAL B 1 65  ? 213.150 238.353 194.142 1.00 15.96  ? 65  VAL B C     1 
ATOM   2239  O  O     . VAL B 1 65  ? 213.317 237.697 195.162 1.00 16.60  ? 65  VAL B O     1 
ATOM   2240  C  CB    . VAL B 1 65  ? 210.999 237.563 193.075 1.00 15.53  ? 65  VAL B CB    1 
ATOM   2241  C  CG1   . VAL B 1 65  ? 209.528 237.871 192.891 1.00 15.92  ? 65  VAL B CG1   1 
ATOM   2242  C  CG2   . VAL B 1 65  ? 211.618 237.149 191.752 1.00 15.41  ? 65  VAL B CG2   1 
ATOM   2243  N  N     . THR B 1 66  ? 214.160 238.719 193.356 1.00 17.41  ? 66  THR B N     1 
ATOM   2244  C  CA    . THR B 1 66  ? 215.531 238.328 193.646 1.00 19.37  ? 66  THR B CA    1 
ATOM   2245  C  C     . THR B 1 66  ? 216.145 239.146 194.781 1.00 21.89  ? 66  THR B C     1 
ATOM   2246  O  O     . THR B 1 66  ? 217.226 238.781 195.259 1.00 24.59  ? 66  THR B O     1 
ATOM   2247  C  CB    . THR B 1 66  ? 216.391 238.435 192.393 1.00 19.69  ? 66  THR B CB    1 
ATOM   2248  O  OG1   . THR B 1 66  ? 216.504 239.806 192.031 1.00 19.32  ? 66  THR B OG1   1 
ATOM   2249  C  CG2   . THR B 1 66  ? 215.803 237.629 191.251 1.00 20.34  ? 66  THR B CG2   1 
ATOM   2250  N  N     . SER B 1 67  ? 215.496 240.243 195.202 1.00 21.36  ? 67  SER B N     1 
ATOM   2251  C  CA    . SER B 1 67  ? 216.070 241.118 196.216 1.00 22.25  ? 67  SER B CA    1 
ATOM   2252  C  C     . SER B 1 67  ? 215.249 241.061 197.493 1.00 20.15  ? 67  SER B C     1 
ATOM   2253  O  O     . SER B 1 67  ? 214.028 241.141 197.458 1.00 19.85  ? 67  SER B O     1 
ATOM   2254  C  CB    . SER B 1 67  ? 216.218 242.544 195.749 1.00 24.91  ? 67  SER B CB    1 
ATOM   2255  O  OG    . SER B 1 67  ? 214.958 243.094 195.499 1.00 25.59  ? 67  SER B OG    1 
ATOM   2256  N  N     . GLU B 1 68  ? 215.937 240.885 198.626 1.00 21.18  ? 68  GLU B N     1 
ATOM   2257  C  CA    . GLU B 1 68  ? 215.305 240.818 199.930 1.00 22.65  ? 68  GLU B CA    1 
ATOM   2258  C  C     . GLU B 1 68  ? 214.566 242.119 200.241 1.00 23.40  ? 68  GLU B C     1 
ATOM   2259  O  O     . GLU B 1 68  ? 213.455 242.075 200.759 1.00 22.36  ? 68  GLU B O     1 
ATOM   2260  C  CB    . GLU B 1 68  ? 216.363 240.532 200.992 1.00 23.94  ? 68  GLU B CB    1 
ATOM   2261  C  CG    . GLU B 1 68  ? 215.786 240.456 202.398 1.00 28.28  ? 68  GLU B CG    1 
ATOM   2262  C  CD    . GLU B 1 68  ? 216.799 240.019 203.444 1.00 33.18  ? 68  GLU B CD    1 
ATOM   2263  O  OE1   . GLU B 1 68  ? 217.981 239.839 203.081 1.00 35.24  ? 68  GLU B OE1   1 
ATOM   2264  O  OE2   . GLU B 1 68  ? 216.413 239.864 204.625 1.00 41.68  ? 68  GLU B OE2   1 
ATOM   2265  N  N     . LYS B 1 69  ? 215.174 243.272 199.932 1.00 24.34  ? 69  LYS B N     1 
ATOM   2266  C  CA    . LYS B 1 69  ? 214.580 244.553 200.276 1.00 25.85  ? 69  LYS B CA    1 
ATOM   2267  C  C     . LYS B 1 69  ? 213.258 244.770 199.535 1.00 23.58  ? 69  LYS B C     1 
ATOM   2268  O  O     . LYS B 1 69  ? 212.288 245.230 200.133 1.00 22.65  ? 69  LYS B O     1 
ATOM   2269  C  CB    . LYS B 1 69  ? 215.561 245.689 199.962 1.00 31.27  ? 69  LYS B CB    1 
ATOM   2270  C  CG    . LYS B 1 69  ? 215.023 247.068 200.298 1.00 39.03  ? 69  LYS B CG    1 
ATOM   2271  C  CD    . LYS B 1 69  ? 216.080 248.161 200.258 1.00 47.52  ? 69  LYS B CD    1 
ATOM   2272  C  CE    . LYS B 1 69  ? 216.695 248.320 198.901 1.00 53.19  ? 69  LYS B CE    1 
ATOM   2273  N  NZ    . LYS B 1 69  ? 217.637 249.445 198.871 1.00 57.36  ? 69  LYS B NZ    1 
ATOM   2274  N  N     . ASP B 1 70  ? 213.220 244.452 198.238 1.00 22.40  ? 70  ASP B N     1 
ATOM   2275  C  CA    . ASP B 1 70  ? 212.023 244.686 197.444 1.00 21.78  ? 70  ASP B CA    1 
ATOM   2276  C  C     . ASP B 1 70  ? 210.864 243.831 197.944 1.00 19.61  ? 70  ASP B C     1 
ATOM   2277  O  O     . ASP B 1 70  ? 209.743 244.310 198.061 1.00 19.74  ? 70  ASP B O     1 
ATOM   2278  C  CB    . ASP B 1 70  ? 212.269 244.428 195.965 1.00 24.44  ? 70  ASP B CB    1 
ATOM   2279  C  CG    . ASP B 1 70  ? 212.971 245.572 195.256 1.00 29.09  ? 70  ASP B CG    1 
ATOM   2280  O  OD1   . ASP B 1 70  ? 213.555 246.414 195.985 1.00 32.26  ? 70  ASP B OD1   1 
ATOM   2281  O  OD2   . ASP B 1 70  ? 212.916 245.647 194.004 1.00 32.33  ? 70  ASP B OD2   1 
ATOM   2282  N  N     . VAL B 1 71  ? 211.130 242.561 198.255 1.00 17.42  ? 71  VAL B N     1 
ATOM   2283  C  CA    . VAL B 1 71  ? 210.080 241.676 198.718 1.00 17.20  ? 71  VAL B CA    1 
ATOM   2284  C  C     . VAL B 1 71  ? 209.604 242.104 200.103 1.00 17.52  ? 71  VAL B C     1 
ATOM   2285  O  O     . VAL B 1 71  ? 208.408 242.054 200.398 1.00 17.93  ? 71  VAL B O     1 
ATOM   2286  C  CB    . VAL B 1 71  ? 210.534 240.208 198.703 1.00 16.17  ? 71  VAL B CB    1 
ATOM   2287  C  CG1   . VAL B 1 71  ? 209.460 239.290 199.252 1.00 16.09  ? 71  VAL B CG1   1 
ATOM   2288  C  CG2   . VAL B 1 71  ? 210.918 239.776 197.301 1.00 16.25  ? 71  VAL B CG2   1 
ATOM   2289  N  N     . GLN B 1 72  ? 210.532 242.532 200.957 1.00 18.86  ? 72  GLN B N     1 
ATOM   2290  C  CA    . GLN B 1 72  ? 210.164 243.026 202.277 1.00 19.98  ? 72  GLN B CA    1 
ATOM   2291  C  C     . GLN B 1 72  ? 209.251 244.243 202.153 1.00 18.86  ? 72  GLN B C     1 
ATOM   2292  O  O     . GLN B 1 72  ? 208.276 244.361 202.890 1.00 18.40  ? 72  GLN B O     1 
ATOM   2293  C  CB    . GLN B 1 72  ? 211.402 243.354 203.105 1.00 21.46  ? 72  GLN B CB    1 
ATOM   2294  C  CG    . GLN B 1 72  ? 212.099 242.128 203.683 1.00 23.02  ? 72  GLN B CG    1 
ATOM   2295  C  CD    . GLN B 1 72  ? 213.395 242.477 204.384 1.00 25.83  ? 72  GLN B CD    1 
ATOM   2296  O  OE1   . GLN B 1 72  ? 214.123 243.391 203.974 1.00 26.45  ? 72  GLN B OE1   1 
ATOM   2297  N  NE2   . GLN B 1 72  ? 213.719 241.724 205.426 1.00 27.58  ? 72  GLN B NE2   1 
ATOM   2298  N  N     . THR B 1 73  ? 209.570 245.154 201.232 1.00 19.44  ? 73  THR B N     1 
ATOM   2299  C  CA    . THR B 1 73  ? 208.734 246.326 200.998 1.00 20.71  ? 73  THR B CA    1 
ATOM   2300  C  C     . THR B 1 73  ? 207.353 245.905 200.494 1.00 20.81  ? 73  THR B C     1 
ATOM   2301  O  O     . THR B 1 73  ? 206.345 246.450 200.934 1.00 21.46  ? 73  THR B O     1 
ATOM   2302  C  CB    . THR B 1 73  ? 209.412 247.267 200.006 1.00 21.89  ? 73  THR B CB    1 
ATOM   2303  O  OG1   . THR B 1 73  ? 210.665 247.665 200.555 1.00 23.11  ? 73  THR B OG1   1 
ATOM   2304  C  CG2   . THR B 1 73  ? 208.569 248.489 199.700 1.00 22.50  ? 73  THR B CG2   1 
ATOM   2305  N  N     . ALA B 1 74  ? 207.305 244.940 199.569 1.00 20.50  ? 74  ALA B N     1 
ATOM   2306  C  CA    . ALA B 1 74  ? 206.039 244.475 199.024 1.00 20.23  ? 74  ALA B CA    1 
ATOM   2307  C  C     . ALA B 1 74  ? 205.183 243.826 200.109 1.00 19.80  ? 74  ALA B C     1 
ATOM   2308  O  O     . ALA B 1 74  ? 203.978 244.063 200.182 1.00 19.72  ? 74  ALA B O     1 
ATOM   2309  C  CB    . ALA B 1 74  ? 206.276 243.526 197.872 1.00 20.48  ? 74  ALA B CB    1 
ATOM   2310  N  N     . LEU B 1 75  ? 205.799 243.001 200.958 1.00 19.44  ? 75  LEU B N     1 
ATOM   2311  C  CA    . LEU B 1 75  ? 205.054 242.332 202.014 1.00 19.48  ? 75  LEU B CA    1 
ATOM   2312  C  C     . LEU B 1 75  ? 204.574 243.337 203.059 1.00 19.98  ? 75  LEU B C     1 
ATOM   2313  O  O     . LEU B 1 75  ? 203.505 243.167 203.635 1.00 20.54  ? 75  LEU B O     1 
ATOM   2314  C  CB    . LEU B 1 75  ? 205.897 241.230 202.645 1.00 19.25  ? 75  LEU B CB    1 
ATOM   2315  C  CG    . LEU B 1 75  ? 206.181 240.031 201.743 1.00 19.30  ? 75  LEU B CG    1 
ATOM   2316  C  CD1   . LEU B 1 75  ? 207.130 239.051 202.419 1.00 19.66  ? 75  LEU B CD1   1 
ATOM   2317  C  CD2   . LEU B 1 75  ? 204.887 239.340 201.356 1.00 20.05  ? 75  LEU B CD2   1 
ATOM   2318  N  N     . ALA B 1 76  ? 205.364 244.381 203.318 1.00 21.43  ? 76  ALA B N     1 
ATOM   2319  C  CA    . ALA B 1 76  ? 204.930 245.452 204.207 1.00 22.49  ? 76  ALA B CA    1 
ATOM   2320  C  C     . ALA B 1 76  ? 203.724 246.176 203.614 1.00 22.17  ? 76  ALA B C     1 
ATOM   2321  O  O     . ALA B 1 76  ? 202.801 246.541 204.336 1.00 22.99  ? 76  ALA B O     1 
ATOM   2322  C  CB    . ALA B 1 76  ? 206.068 246.407 204.477 1.00 22.78  ? 76  ALA B CB    1 
ATOM   2323  N  N     . LEU B 1 77  ? 203.728 246.382 202.293 1.00 22.96  ? 77  LEU B N     1 
ATOM   2324  C  CA    . LEU B 1 77  ? 202.589 246.984 201.615 1.00 23.05  ? 77  LEU B CA    1 
ATOM   2325  C  C     . LEU B 1 77  ? 201.363 246.081 201.740 1.00 24.14  ? 77  LEU B C     1 
ATOM   2326  O  O     . LEU B 1 77  ? 200.259 246.567 201.984 1.00 25.32  ? 77  LEU B O     1 
ATOM   2327  C  CB    . LEU B 1 77  ? 202.958 247.253 200.156 1.00 26.02  ? 77  LEU B CB    1 
ATOM   2328  C  CG    . LEU B 1 77  ? 201.968 248.041 199.295 1.00 27.93  ? 77  LEU B CG    1 
ATOM   2329  C  CD1   . LEU B 1 77  ? 202.729 248.773 198.209 1.00 29.97  ? 77  LEU B CD1   1 
ATOM   2330  C  CD2   . LEU B 1 77  ? 200.930 247.163 198.633 1.00 30.11  ? 77  LEU B CD2   1 
ATOM   2331  N  N     . ALA B 1 78  ? 201.554 244.765 201.574 1.00 24.87  ? 78  ALA B N     1 
ATOM   2332  C  CA    . ALA B 1 78  ? 200.454 243.819 201.694 1.00 23.74  ? 78  ALA B CA    1 
ATOM   2333  C  C     . ALA B 1 78  ? 199.882 243.845 203.107 1.00 23.86  ? 78  ALA B C     1 
ATOM   2334  O  O     . ALA B 1 78  ? 198.670 243.831 203.289 1.00 25.78  ? 78  ALA B O     1 
ATOM   2335  C  CB    . ALA B 1 78  ? 200.906 242.408 201.324 1.00 23.25  ? 78  ALA B CB    1 
ATOM   2336  N  N     . LYS B 1 79  ? 200.755 243.856 204.116 1.00 25.39  ? 79  LYS B N     1 
ATOM   2337  C  CA    . LYS B 1 79  ? 200.311 243.889 205.499 1.00 27.60  ? 79  LYS B CA    1 
ATOM   2338  C  C     . LYS B 1 79  ? 199.598 245.207 205.801 1.00 27.21  ? 79  LYS B C     1 
ATOM   2339  O  O     . LYS B 1 79  ? 198.598 245.221 206.508 1.00 27.29  ? 79  LYS B O     1 
ATOM   2340  C  CB    . LYS B 1 79  ? 201.501 243.685 206.438 1.00 30.48  ? 79  LYS B CB    1 
ATOM   2341  C  CG    . LYS B 1 79  ? 201.149 243.633 207.905 1.00 34.69  ? 79  LYS B CG    1 
ATOM   2342  C  CD    . LYS B 1 79  ? 202.291 243.061 208.734 1.00 39.88  ? 79  LYS B CD    1 
ATOM   2343  C  CE    . LYS B 1 79  ? 201.851 242.520 210.055 1.00 44.62  ? 79  LYS B CE    1 
ATOM   2344  N  NZ    . LYS B 1 79  ? 201.745 243.557 211.086 1.00 45.58  ? 79  LYS B NZ    1 
ATOM   2345  N  N     . GLY B 1 80  ? 200.120 246.319 205.283 1.00 27.58  ? 80  GLY B N     1 
ATOM   2346  C  CA    . GLY B 1 80  ? 199.505 247.616 205.530 1.00 28.56  ? 80  GLY B CA    1 
ATOM   2347  C  C     . GLY B 1 80  ? 198.111 247.716 204.914 1.00 28.01  ? 80  GLY B C     1 
ATOM   2348  O  O     . GLY B 1 80  ? 197.185 248.242 205.524 1.00 31.13  ? 80  GLY B O     1 
ATOM   2349  N  N     . LYS B 1 81  ? 197.960 247.214 203.689 1.00 28.77  ? 81  LYS B N     1 
ATOM   2350  C  CA    . LYS B 1 81  ? 196.710 247.363 202.966 1.00 28.40  ? 81  LYS B CA    1 
ATOM   2351  C  C     . LYS B 1 81  ? 195.645 246.391 203.470 1.00 27.14  ? 81  LYS B C     1 
ATOM   2352  O  O     . LYS B 1 81  ? 194.483 246.765 203.586 1.00 28.48  ? 81  LYS B O     1 
ATOM   2353  C  CB    . LYS B 1 81  ? 196.947 247.168 201.467 1.00 31.09  ? 81  LYS B CB    1 
ATOM   2354  C  CG    . LYS B 1 81  ? 195.709 247.379 200.616 1.00 33.78  ? 81  LYS B CG    1 
ATOM   2355  C  CD    . LYS B 1 81  ? 194.959 248.671 200.914 1.00 37.76  ? 81  LYS B CD    1 
ATOM   2356  C  CE    . LYS B 1 81  ? 194.107 249.118 199.774 1.00 40.38  ? 81  LYS B CE    1 
ATOM   2357  N  NZ    . LYS B 1 81  ? 193.219 248.031 199.369 1.00 41.29  ? 81  LYS B NZ    1 
ATOM   2358  N  N     . PHE B 1 82  ? 196.031 245.138 203.757 1.00 25.25  ? 82  PHE B N     1 
ATOM   2359  C  CA    . PHE B 1 82  ? 195.056 244.089 204.024 1.00 23.77  ? 82  PHE B CA    1 
ATOM   2360  C  C     . PHE B 1 82  ? 195.195 243.466 205.410 1.00 22.16  ? 82  PHE B C     1 
ATOM   2361  O  O     . PHE B 1 82  ? 194.313 242.709 205.808 1.00 24.20  ? 82  PHE B O     1 
ATOM   2362  C  CB    . PHE B 1 82  ? 195.170 242.983 202.974 1.00 23.15  ? 82  PHE B CB    1 
ATOM   2363  C  CG    . PHE B 1 82  ? 194.793 243.438 201.579 1.00 22.54  ? 82  PHE B CG    1 
ATOM   2364  C  CD1   . PHE B 1 82  ? 193.566 244.035 201.329 1.00 22.78  ? 82  PHE B CD1   1 
ATOM   2365  C  CD2   . PHE B 1 82  ? 195.689 243.296 200.527 1.00 22.31  ? 82  PHE B CD2   1 
ATOM   2366  C  CE1   . PHE B 1 82  ? 193.241 244.463 200.055 1.00 22.66  ? 82  PHE B CE1   1 
ATOM   2367  C  CE2   . PHE B 1 82  ? 195.351 243.714 199.255 1.00 22.34  ? 82  PHE B CE2   1 
ATOM   2368  C  CZ    . PHE B 1 82  ? 194.132 244.306 199.022 1.00 22.96  ? 82  PHE B CZ    1 
ATOM   2369  N  N     . GLY B 1 83  ? 196.291 243.724 206.129 1.00 21.26  ? 83  GLY B N     1 
ATOM   2370  C  CA    . GLY B 1 83  ? 196.404 243.316 207.521 1.00 21.52  ? 83  GLY B CA    1 
ATOM   2371  C  C     . GLY B 1 83  ? 197.120 241.976 207.718 1.00 21.98  ? 83  GLY B C     1 
ATOM   2372  O  O     . GLY B 1 83  ? 197.598 241.684 208.811 1.00 22.86  ? 83  GLY B O     1 
ATOM   2373  N  N     . ARG B 1 84  ? 197.198 241.155 206.673 1.00 20.19  ? 84  ARG B N     1 
ATOM   2374  C  CA    . ARG B 1 84  ? 197.728 239.810 206.811 1.00 19.67  ? 84  ARG B CA    1 
ATOM   2375  C  C     . ARG B 1 84  ? 197.991 239.243 205.420 1.00 18.47  ? 84  ARG B C     1 
ATOM   2376  O  O     . ARG B 1 84  ? 197.589 239.821 204.412 1.00 18.57  ? 84  ARG B O     1 
ATOM   2377  C  CB    . ARG B 1 84  ? 196.766 238.886 207.565 1.00 20.34  ? 84  ARG B CB    1 
ATOM   2378  C  CG    . ARG B 1 84  ? 195.408 238.762 206.890 1.00 22.37  ? 84  ARG B CG    1 
ATOM   2379  C  CD    . ARG B 1 84  ? 194.397 238.022 207.728 1.00 24.77  ? 84  ARG B CD    1 
ATOM   2380  N  NE    . ARG B 1 84  ? 194.713 236.593 207.835 1.00 25.19  ? 84  ARG B NE    1 
ATOM   2381  C  CZ    . ARG B 1 84  ? 194.623 235.877 208.944 1.00 28.48  ? 84  ARG B CZ    1 
ATOM   2382  N  NH1   . ARG B 1 84  ? 194.238 236.431 210.085 1.00 31.87  ? 84  ARG B NH1   1 
ATOM   2383  N  NH2   . ARG B 1 84  ? 194.870 234.581 208.923 1.00 27.36  ? 84  ARG B NH2   1 
ATOM   2384  N  N     . VAL B 1 85  ? 198.726 238.127 205.396 1.00 16.86  ? 85  VAL B N     1 
ATOM   2385  C  CA    . VAL B 1 85  ? 198.935 237.356 204.190 1.00 15.59  ? 85  VAL B CA    1 
ATOM   2386  C  C     . VAL B 1 85  ? 198.562 235.910 204.489 1.00 13.70  ? 85  VAL B C     1 
ATOM   2387  O  O     . VAL B 1 85  ? 199.114 235.306 205.395 1.00 13.91  ? 85  VAL B O     1 
ATOM   2388  C  CB    . VAL B 1 85  ? 200.384 237.476 203.684 1.00 16.85  ? 85  VAL B CB    1 
ATOM   2389  C  CG1   . VAL B 1 85  ? 200.633 236.560 202.499 1.00 16.86  ? 85  VAL B CG1   1 
ATOM   2390  C  CG2   . VAL B 1 85  ? 200.713 238.906 203.293 1.00 16.85  ? 85  VAL B CG2   1 
ATOM   2391  N  N     . ASP B 1 86  ? 197.662 235.352 203.677 1.00 13.10  ? 86  ASP B N     1 
ATOM   2392  C  CA    . ASP B 1 86  ? 197.202 233.982 203.838 1.00 13.36  ? 86  ASP B CA    1 
ATOM   2393  C  C     . ASP B 1 86  ? 197.777 233.051 202.772 1.00 11.52  ? 86  ASP B C     1 
ATOM   2394  O  O     . ASP B 1 86  ? 197.972 231.873 203.041 1.00 11.22  ? 86  ASP B O     1 
ATOM   2395  C  CB    . ASP B 1 86  ? 195.688 233.916 203.797 1.00 14.53  ? 86  ASP B CB    1 
ATOM   2396  C  CG    . ASP B 1 86  ? 195.033 234.751 204.885 1.00 16.94  ? 86  ASP B CG    1 
ATOM   2397  O  OD1   . ASP B 1 86  ? 195.319 234.486 206.086 1.00 19.27  ? 86  ASP B OD1   1 
ATOM   2398  O  OD2   . ASP B 1 86  ? 194.260 235.665 204.526 1.00 17.96  ? 86  ASP B OD2   1 
ATOM   2399  N  N     . VAL B 1 87  ? 197.991 233.571 201.563 1.00 10.44  ? 87  VAL B N     1 
ATOM   2400  C  CA    . VAL B 1 87  ? 198.395 232.758 200.433 1.00 9.81   ? 87  VAL B CA    1 
ATOM   2401  C  C     . VAL B 1 87  ? 199.535 233.467 199.723 1.00 9.48   ? 87  VAL B C     1 
ATOM   2402  O  O     . VAL B 1 87  ? 199.492 234.681 199.519 1.00 10.38  ? 87  VAL B O     1 
ATOM   2403  C  CB    . VAL B 1 87  ? 197.211 232.501 199.480 1.00 9.74   ? 87  VAL B CB    1 
ATOM   2404  C  CG1   . VAL B 1 87  ? 197.635 231.745 198.230 1.00 9.91   ? 87  VAL B CG1   1 
ATOM   2405  C  CG2   . VAL B 1 87  ? 196.092 231.747 200.181 1.00 9.77   ? 87  VAL B CG2   1 
ATOM   2406  N  N     . ALA B 1 88  ? 200.545 232.691 199.328 1.00 9.01   ? 88  ALA B N     1 
ATOM   2407  C  CA    . ALA B 1 88  ? 201.581 233.167 198.432 1.00 9.05   ? 88  ALA B CA    1 
ATOM   2408  C  C     . ALA B 1 88  ? 201.582 232.272 197.196 1.00 8.94   ? 88  ALA B C     1 
ATOM   2409  O  O     . ALA B 1 88  ? 201.646 231.050 197.316 1.00 8.63   ? 88  ALA B O     1 
ATOM   2410  C  CB    . ALA B 1 88  ? 202.930 233.177 199.118 1.00 9.03   ? 88  ALA B CB    1 
ATOM   2411  N  N     . VAL B 1 89  ? 201.499 232.894 196.024 1.00 9.22   ? 89  VAL B N     1 
ATOM   2412  C  CA    . VAL B 1 89  ? 201.596 232.189 194.760 1.00 9.79   ? 89  VAL B CA    1 
ATOM   2413  C  C     . VAL B 1 89  ? 202.806 232.715 193.999 1.00 9.85   ? 89  VAL B C     1 
ATOM   2414  O  O     . VAL B 1 89  ? 202.816 233.873 193.581 1.00 10.49  ? 89  VAL B O     1 
ATOM   2415  C  CB    . VAL B 1 89  ? 200.306 232.361 193.940 1.00 9.77   ? 89  VAL B CB    1 
ATOM   2416  C  CG1   . VAL B 1 89  ? 200.355 231.456 192.715 1.00 10.29  ? 89  VAL B CG1   1 
ATOM   2417  C  CG2   . VAL B 1 89  ? 199.072 232.064 194.773 1.00 10.14  ? 89  VAL B CG2   1 
ATOM   2418  N  N     . ASN B 1 90  ? 203.805 231.859 193.810 1.00 10.17  ? 90  ASN B N     1 
ATOM   2419  C  CA    . ASN B 1 90  ? 205.021 232.213 193.104 1.00 11.14  ? 90  ASN B CA    1 
ATOM   2420  C  C     . ASN B 1 90  ? 204.842 231.903 191.621 1.00 12.61  ? 90  ASN B C     1 
ATOM   2421  O  O     . ASN B 1 90  ? 204.946 230.756 191.209 1.00 12.34  ? 90  ASN B O     1 
ATOM   2422  C  CB    . ASN B 1 90  ? 206.222 231.459 193.656 1.00 11.84  ? 90  ASN B CB    1 
ATOM   2423  C  CG    . ASN B 1 90  ? 206.654 231.977 195.001 1.00 12.58  ? 90  ASN B CG    1 
ATOM   2424  O  OD1   . ASN B 1 90  ? 207.236 233.065 195.081 1.00 13.67  ? 90  ASN B OD1   1 
ATOM   2425  N  ND2   . ASN B 1 90  ? 206.437 231.210 196.059 1.00 12.65  ? 90  ASN B ND2   1 
ATOM   2426  N  N     . CYS B 1 91  ? 204.580 232.941 190.823 1.00 13.71  ? 91  CYS B N     1 
ATOM   2427  C  CA    . CYS B 1 91  ? 204.446 232.784 189.383 1.00 16.07  ? 91  CYS B CA    1 
ATOM   2428  C  C     . CYS B 1 91  ? 205.492 233.587 188.610 1.00 18.55  ? 91  CYS B C     1 
ATOM   2429  O  O     . CYS B 1 91  ? 205.494 233.567 187.382 1.00 20.55  ? 91  CYS B O     1 
ATOM   2430  C  CB    . CYS B 1 91  ? 203.071 233.226 188.898 1.00 16.88  ? 91  CYS B CB    1 
ATOM   2431  S  SG    . CYS B 1 91  ? 201.716 232.193 189.515 1.00 19.94  ? 91  CYS B SG    1 
ATOM   2432  N  N     . ALA B 1 92  ? 206.349 234.345 189.309 1.00 18.89  ? 92  ALA B N     1 
ATOM   2433  C  CA    . ALA B 1 92  ? 207.397 235.093 188.644 1.00 19.58  ? 92  ALA B CA    1 
ATOM   2434  C  C     . ALA B 1 92  ? 208.431 234.122 188.081 1.00 22.00  ? 92  ALA B C     1 
ATOM   2435  O  O     . ALA B 1 92  ? 208.825 233.152 188.730 1.00 25.46  ? 92  ALA B O     1 
ATOM   2436  C  CB    . ALA B 1 92  ? 208.025 236.055 189.617 1.00 19.30  ? 92  ALA B CB    1 
ATOM   2437  N  N     . GLY B 1 93  ? 208.884 234.390 186.867 1.00 23.50  ? 93  GLY B N     1 
ATOM   2438  C  CA    . GLY B 1 93  ? 209.855 233.505 186.260 1.00 26.21  ? 93  GLY B CA    1 
ATOM   2439  C  C     . GLY B 1 93  ? 210.240 233.990 184.872 1.00 27.60  ? 93  GLY B C     1 
ATOM   2440  O  O     . GLY B 1 93  ? 209.494 234.726 184.233 1.00 29.61  ? 93  GLY B O     1 
ATOM   2441  N  N     . ILE B 1 94  ? 211.428 233.560 184.440 1.00 27.48  ? 94  ILE B N     1 
ATOM   2442  C  CA    . ILE B 1 94  ? 211.917 233.824 183.099 1.00 27.95  ? 94  ILE B CA    1 
ATOM   2443  C  C     . ILE B 1 94  ? 212.420 232.508 182.518 1.00 27.11  ? 94  ILE B C     1 
ATOM   2444  O  O     . ILE B 1 94  ? 212.500 231.491 183.194 1.00 29.07  ? 94  ILE B O     1 
ATOM   2445  C  CB    . ILE B 1 94  ? 213.017 234.901 183.107 1.00 26.96  ? 94  ILE B CB    1 
ATOM   2446  C  CG1   . ILE B 1 94  ? 214.213 234.449 183.918 1.00 28.36  ? 94  ILE B CG1   1 
ATOM   2447  C  CG2   . ILE B 1 94  ? 212.468 236.241 183.585 1.00 27.47  ? 94  ILE B CG2   1 
ATOM   2448  C  CD1   . ILE B 1 94  ? 215.385 235.412 183.876 1.00 30.08  ? 94  ILE B CD1   1 
ATOM   2449  N  N     . ALA B 1 95  ? 212.784 232.535 181.240 1.00 29.71  ? 95  ALA B N     1 
ATOM   2450  C  CA    . ALA B 1 95  ? 213.388 231.388 180.584 1.00 30.03  ? 95  ALA B CA    1 
ATOM   2451  C  C     . ALA B 1 95  ? 214.437 231.872 179.596 1.00 30.01  ? 95  ALA B C     1 
ATOM   2452  O  O     . ALA B 1 95  ? 214.408 233.008 179.130 1.00 29.57  ? 95  ALA B O     1 
ATOM   2453  C  CB    . ALA B 1 95  ? 212.333 230.546 179.904 1.00 30.71  ? 95  ALA B CB    1 
ATOM   2454  N  N     . VAL B 1 96  ? 215.372 230.973 179.290 1.00 30.18  ? 96  VAL B N     1 
ATOM   2455  C  CA    . VAL B 1 96  ? 216.319 231.162 178.210 1.00 31.32  ? 96  VAL B CA    1 
ATOM   2456  C  C     . VAL B 1 96  ? 216.269 229.912 177.339 1.00 30.68  ? 96  VAL B C     1 
ATOM   2457  O  O     . VAL B 1 96  ? 215.947 228.816 177.808 1.00 32.71  ? 96  VAL B O     1 
ATOM   2458  C  CB    . VAL B 1 96  ? 217.742 231.422 178.737 1.00 33.79  ? 96  VAL B CB    1 
ATOM   2459  C  CG1   . VAL B 1 96  ? 218.394 230.153 179.275 1.00 32.96  ? 96  VAL B CG1   1 
ATOM   2460  C  CG2   . VAL B 1 96  ? 218.627 232.049 177.674 1.00 36.81  ? 96  VAL B CG2   1 
ATOM   2461  N  N     . ALA B 1 97  ? 216.597 230.092 176.065 1.00 29.64  ? 97  ALA B N     1 
ATOM   2462  C  CA    . ALA B 1 97  ? 216.722 228.989 175.127 1.00 27.70  ? 97  ALA B CA    1 
ATOM   2463  C  C     . ALA B 1 97  ? 218.166 228.978 174.645 1.00 27.68  ? 97  ALA B C     1 
ATOM   2464  O  O     . ALA B 1 97  ? 218.569 229.813 173.835 1.00 28.88  ? 97  ALA B O     1 
ATOM   2465  C  CB    . ALA B 1 97  ? 215.734 229.125 173.976 1.00 29.87  ? 97  ALA B CB    1 
ATOM   2466  N  N     . SER B 1 98  ? 218.952 228.041 175.182 1.00 25.08  ? 98  SER B N     1 
ATOM   2467  C  CA    . SER B 1 98  ? 220.364 227.961 174.866 1.00 23.36  ? 98  SER B CA    1 
ATOM   2468  C  C     . SER B 1 98  ? 220.836 226.536 175.110 1.00 22.26  ? 98  SER B C     1 
ATOM   2469  O  O     . SER B 1 98  ? 220.629 225.991 176.189 1.00 22.86  ? 98  SER B O     1 
ATOM   2470  C  CB    . SER B 1 98  ? 221.153 228.952 175.691 1.00 24.27  ? 98  SER B CB    1 
ATOM   2471  O  OG    . SER B 1 98  ? 222.530 228.936 175.343 1.00 25.93  ? 98  SER B OG    1 
ATOM   2472  N  N     . LYS B 1 99  ? 221.489 225.944 174.111 1.00 22.01  ? 99  LYS B N     1 
ATOM   2473  C  CA    . LYS B 1 99  ? 222.071 224.628 174.278 1.00 22.22  ? 99  LYS B CA    1 
ATOM   2474  C  C     . LYS B 1 99  ? 223.265 224.708 175.225 1.00 20.99  ? 99  LYS B C     1 
ATOM   2475  O  O     . LYS B 1 99  ? 223.936 225.732 175.324 1.00 21.58  ? 99  LYS B O     1 
ATOM   2476  C  CB    . LYS B 1 99  ? 222.536 224.044 172.942 1.00 24.83  ? 99  LYS B CB    1 
ATOM   2477  C  CG    . LYS B 1 99  ? 221.454 223.820 171.924 1.00 26.45  ? 99  LYS B CG    1 
ATOM   2478  C  CD    . LYS B 1 99  ? 221.837 222.773 170.895 1.00 29.07  ? 99  LYS B CD    1 
ATOM   2479  C  CE    . LYS B 1 99  ? 220.792 222.599 169.846 1.00 30.94  ? 99  LYS B CE    1 
ATOM   2480  N  NZ    . LYS B 1 99  ? 221.403 222.009 168.649 1.00 32.91  ? 99  LYS B NZ    1 
ATOM   2481  N  N     . THR B 1 100 ? 223.520 223.606 175.936 1.00 19.95  ? 100 THR B N     1 
ATOM   2482  C  CA    . THR B 1 100 ? 224.672 223.510 176.812 1.00 19.19  ? 100 THR B CA    1 
ATOM   2483  C  C     . THR B 1 100 ? 225.942 223.731 175.992 1.00 20.51  ? 100 THR B C     1 
ATOM   2484  O  O     . THR B 1 100 ? 226.838 224.452 176.421 1.00 20.19  ? 100 THR B O     1 
ATOM   2485  C  CB    . THR B 1 100 ? 224.681 222.146 177.507 1.00 19.08  ? 100 THR B CB    1 
ATOM   2486  O  OG1   . THR B 1 100 ? 223.507 222.056 178.314 1.00 20.20  ? 100 THR B OG1   1 
ATOM   2487  C  CG2   . THR B 1 100 ? 225.914 221.958 178.371 1.00 18.99  ? 100 THR B CG2   1 
ATOM   2488  N  N     . TYR B 1 101 ? 226.042 223.040 174.850 1.00 20.57  ? 101 TYR B N     1 
ATOM   2489  C  CA    . TYR B 1 101 ? 227.184 223.185 173.969 1.00 22.69  ? 101 TYR B CA    1 
ATOM   2490  C  C     . TYR B 1 101 ? 226.764 222.767 172.566 1.00 25.18  ? 101 TYR B C     1 
ATOM   2491  O  O     . TYR B 1 101 ? 226.107 221.741 172.391 1.00 23.96  ? 101 TYR B O     1 
ATOM   2492  C  CB    . TYR B 1 101 ? 228.373 222.349 174.448 1.00 22.51  ? 101 TYR B CB    1 
ATOM   2493  C  CG    . TYR B 1 101 ? 229.580 222.479 173.537 1.00 23.31  ? 101 TYR B CG    1 
ATOM   2494  C  CD1   . TYR B 1 101 ? 230.301 223.665 173.483 1.00 24.63  ? 101 TYR B CD1   1 
ATOM   2495  C  CD2   . TYR B 1 101 ? 229.977 221.428 172.718 1.00 24.77  ? 101 TYR B CD2   1 
ATOM   2496  C  CE1   . TYR B 1 101 ? 231.396 223.795 172.643 1.00 25.74  ? 101 TYR B CE1   1 
ATOM   2497  C  CE2   . TYR B 1 101 ? 231.075 221.547 171.882 1.00 25.38  ? 101 TYR B CE2   1 
ATOM   2498  C  CZ    . TYR B 1 101 ? 231.771 222.738 171.833 1.00 24.70  ? 101 TYR B CZ    1 
ATOM   2499  O  OH    . TYR B 1 101 ? 232.849 222.833 171.005 1.00 28.16  ? 101 TYR B OH    1 
ATOM   2500  N  N     . ASN B 1 102 ? 227.163 223.578 171.581 1.00 27.41  ? 102 ASN B N     1 
ATOM   2501  C  CA    . ASN B 1 102 ? 226.886 223.303 170.182 1.00 30.40  ? 102 ASN B CA    1 
ATOM   2502  C  C     . ASN B 1 102 ? 228.227 223.080 169.488 1.00 29.25  ? 102 ASN B C     1 
ATOM   2503  O  O     . ASN B 1 102 ? 228.993 224.023 169.294 1.00 29.27  ? 102 ASN B O     1 
ATOM   2504  C  CB    . ASN B 1 102 ? 226.098 224.447 169.544 1.00 32.09  ? 102 ASN B CB    1 
ATOM   2505  C  CG    . ASN B 1 102 ? 225.534 224.097 168.185 1.00 34.05  ? 102 ASN B CG    1 
ATOM   2506  O  OD1   . ASN B 1 102 ? 226.117 223.298 167.438 1.00 33.69  ? 102 ASN B OD1   1 
ATOM   2507  N  ND2   . ASN B 1 102 ? 224.382 224.665 167.861 1.00 35.44  ? 102 ASN B ND2   1 
ATOM   2508  N  N     . LEU B 1 103 ? 228.507 221.827 169.122 1.00 29.76  ? 103 LEU B N     1 
ATOM   2509  C  CA    . LEU B 1 103 ? 229.788 221.479 168.527 1.00 32.39  ? 103 LEU B CA    1 
ATOM   2510  C  C     . LEU B 1 103 ? 229.950 222.133 167.153 1.00 34.87  ? 103 LEU B C     1 
ATOM   2511  O  O     . LEU B 1 103 ? 231.025 222.634 166.831 1.00 34.89  ? 103 LEU B O     1 
ATOM   2512  C  CB    . LEU B 1 103 ? 229.932 219.964 168.431 1.00 31.02  ? 103 LEU B CB    1 
ATOM   2513  C  CG    . LEU B 1 103 ? 231.204 219.454 167.746 1.00 31.62  ? 103 LEU B CG    1 
ATOM   2514  C  CD1   . LEU B 1 103 ? 232.450 219.918 168.481 1.00 31.41  ? 103 LEU B CD1   1 
ATOM   2515  C  CD2   . LEU B 1 103 ? 231.171 217.939 167.638 1.00 31.26  ? 103 LEU B CD2   1 
ATOM   2516  N  N     . LYS B 1 104 ? 228.886 222.122 166.343 1.00 38.72  ? 104 LYS B N     1 
ATOM   2517  C  CA    . LYS B 1 104 ? 228.957 222.658 164.991 1.00 42.49  ? 104 LYS B CA    1 
ATOM   2518  C  C     . LYS B 1 104 ? 229.291 224.149 165.010 1.00 42.09  ? 104 LYS B C     1 
ATOM   2519  O  O     . LYS B 1 104 ? 230.137 224.605 164.245 1.00 42.93  ? 104 LYS B O     1 
ATOM   2520  C  CB    . LYS B 1 104 ? 227.650 222.386 164.246 1.00 45.47  ? 104 LYS B CB    1 
ATOM   2521  C  CG    . LYS B 1 104 ? 227.443 220.909 163.974 1.00 50.30  ? 104 LYS B CG    1 
ATOM   2522  C  CD    . LYS B 1 104 ? 226.148 220.616 163.233 1.00 55.87  ? 104 LYS B CD    1 
ATOM   2523  C  CE    . LYS B 1 104 ? 225.929 219.151 163.017 1.00 57.53  ? 104 LYS B CE    1 
ATOM   2524  N  NZ    . LYS B 1 104 ? 226.999 218.513 162.243 1.00 57.86  ? 104 LYS B NZ    1 
ATOM   2525  N  N     . LYS B 1 105 ? 228.611 224.904 165.873 1.00 41.31  ? 105 LYS B N     1 
ATOM   2526  C  CA    . LYS B 1 105 ? 228.835 226.337 165.964 1.00 42.52  ? 105 LYS B CA    1 
ATOM   2527  C  C     . LYS B 1 105 ? 229.980 226.679 166.915 1.00 39.80  ? 105 LYS B C     1 
ATOM   2528  O  O     . LYS B 1 105 ? 230.423 227.826 166.944 1.00 41.41  ? 105 LYS B O     1 
ATOM   2529  C  CB    . LYS B 1 105 ? 227.571 227.060 166.427 1.00 50.65  ? 105 LYS B CB    1 
ATOM   2530  C  CG    . LYS B 1 105 ? 226.426 227.022 165.435 1.00 57.71  ? 105 LYS B CG    1 
ATOM   2531  C  CD    . LYS B 1 105 ? 225.356 228.070 165.700 1.00 65.21  ? 105 LYS B CD    1 
ATOM   2532  C  CE    . LYS B 1 105 ? 224.551 227.811 166.937 1.00 70.54  ? 105 LYS B CE    1 
ATOM   2533  N  NZ    . LYS B 1 105 ? 223.587 228.893 167.179 1.00 72.10  ? 105 LYS B NZ    1 
ATOM   2534  N  N     . GLY B 1 106 ? 230.457 225.710 167.706 1.00 36.32  ? 106 GLY B N     1 
ATOM   2535  C  CA    . GLY B 1 106 ? 231.459 225.993 168.720 1.00 35.18  ? 106 GLY B CA    1 
ATOM   2536  C  C     . GLY B 1 106 ? 230.947 226.980 169.768 1.00 33.89  ? 106 GLY B C     1 
ATOM   2537  O  O     . GLY B 1 106 ? 231.708 227.805 170.265 1.00 37.10  ? 106 GLY B O     1 
ATOM   2538  N  N     . GLN B 1 107 ? 229.656 226.882 170.102 1.00 32.20  ? 107 GLN B N     1 
ATOM   2539  C  CA    . GLN B 1 107 ? 229.012 227.820 171.007 1.00 33.41  ? 107 GLN B CA    1 
ATOM   2540  C  C     . GLN B 1 107 ? 228.728 227.123 172.334 1.00 28.51  ? 107 GLN B C     1 
ATOM   2541  O  O     . GLN B 1 107 ? 228.208 226.010 172.359 1.00 26.92  ? 107 GLN B O     1 
ATOM   2542  C  CB    . GLN B 1 107 ? 227.719 228.352 170.394 1.00 37.52  ? 107 GLN B CB    1 
ATOM   2543  C  CG    . GLN B 1 107 ? 226.904 229.239 171.322 1.00 42.41  ? 107 GLN B CG    1 
ATOM   2544  C  CD    . GLN B 1 107 ? 225.688 229.840 170.647 1.00 49.83  ? 107 GLN B CD    1 
ATOM   2545  O  OE1   . GLN B 1 107 ? 225.469 229.691 169.439 1.00 50.36  ? 107 GLN B OE1   1 
ATOM   2546  N  NE2   . GLN B 1 107 ? 224.878 230.538 171.430 1.00 52.57  ? 107 GLN B NE2   1 
ATOM   2547  N  N     . THR B 1 108 ? 229.078 227.814 173.424 1.00 25.85  ? 108 THR B N     1 
ATOM   2548  C  CA    . THR B 1 108 ? 228.893 227.295 174.766 1.00 24.24  ? 108 THR B CA    1 
ATOM   2549  C  C     . THR B 1 108 ? 227.864 228.162 175.477 1.00 21.71  ? 108 THR B C     1 
ATOM   2550  O  O     . THR B 1 108 ? 227.894 229.391 175.388 1.00 20.86  ? 108 THR B O     1 
ATOM   2551  C  CB    . THR B 1 108 ? 230.218 227.281 175.533 1.00 23.54  ? 108 THR B CB    1 
ATOM   2552  O  OG1   . THR B 1 108 ? 231.176 226.508 174.814 1.00 21.62  ? 108 THR B OG1   1 
ATOM   2553  C  CG2   . THR B 1 108 ? 230.056 226.674 176.911 1.00 24.09  ? 108 THR B CG2   1 
ATOM   2554  N  N     . HIS B 1 109 ? 226.975 227.495 176.218 1.00 18.98  ? 109 HIS B N     1 
ATOM   2555  C  CA    . HIS B 1 109 ? 226.010 228.187 177.054 1.00 18.50  ? 109 HIS B CA    1 
ATOM   2556  C  C     . HIS B 1 109 ? 226.766 229.119 177.992 1.00 18.17  ? 109 HIS B C     1 
ATOM   2557  O  O     . HIS B 1 109 ? 227.709 228.707 178.677 1.00 21.30  ? 109 HIS B O     1 
ATOM   2558  C  CB    . HIS B 1 109 ? 225.198 227.163 177.860 1.00 18.15  ? 109 HIS B CB    1 
ATOM   2559  C  CG    . HIS B 1 109 ? 223.989 227.694 178.522 1.00 17.52  ? 109 HIS B CG    1 
ATOM   2560  N  ND1   . HIS B 1 109 ? 224.008 228.773 179.380 1.00 17.52  ? 109 HIS B ND1   1 
ATOM   2561  C  CD2   . HIS B 1 109 ? 222.725 227.254 178.497 1.00 17.56  ? 109 HIS B CD2   1 
ATOM   2562  C  CE1   . HIS B 1 109 ? 222.775 229.008 179.820 1.00 17.45  ? 109 HIS B CE1   1 
ATOM   2563  N  NE2   . HIS B 1 109 ? 221.980 228.089 179.310 1.00 16.74  ? 109 HIS B NE2   1 
ATOM   2564  N  N     . THR B 1 110 ? 226.324 230.368 178.060 1.00 18.08  ? 110 THR B N     1 
ATOM   2565  C  CA    . THR B 1 110 ? 226.975 231.314 178.951 1.00 19.63  ? 110 THR B CA    1 
ATOM   2566  C  C     . THR B 1 110 ? 226.573 231.011 180.390 1.00 19.06  ? 110 THR B C     1 
ATOM   2567  O  O     . THR B 1 110 ? 225.433 230.656 180.671 1.00 19.14  ? 110 THR B O     1 
ATOM   2568  C  CB    . THR B 1 110 ? 226.649 232.758 178.577 1.00 20.69  ? 110 THR B CB    1 
ATOM   2569  O  OG1   . THR B 1 110 ? 225.261 232.975 178.763 1.00 21.41  ? 110 THR B OG1   1 
ATOM   2570  C  CG2   . THR B 1 110 ? 227.006 233.049 177.131 1.00 21.79  ? 110 THR B CG2   1 
ATOM   2571  N  N     . LEU B 1 111 ? 227.528 231.179 181.304 1.00 19.92  ? 111 LEU B N     1 
ATOM   2572  C  CA    . LEU B 1 111 ? 227.264 231.028 182.723 1.00 20.80  ? 111 LEU B CA    1 
ATOM   2573  C  C     . LEU B 1 111 ? 226.297 232.105 183.212 1.00 21.86  ? 111 LEU B C     1 
ATOM   2574  O  O     . LEU B 1 111 ? 225.488 231.836 184.094 1.00 21.25  ? 111 LEU B O     1 
ATOM   2575  C  CB    . LEU B 1 111 ? 228.583 231.063 183.489 1.00 21.37  ? 111 LEU B CB    1 
ATOM   2576  C  CG    . LEU B 1 111 ? 228.519 230.637 184.958 1.00 22.07  ? 111 LEU B CG    1 
ATOM   2577  C  CD1   . LEU B 1 111 ? 227.925 229.244 185.086 1.00 22.18  ? 111 LEU B CD1   1 
ATOM   2578  C  CD2   . LEU B 1 111 ? 229.913 230.716 185.563 1.00 21.36  ? 111 LEU B CD2   1 
ATOM   2579  N  N     . GLU B 1 112 ? 226.368 233.309 182.634 1.00 22.82  ? 112 GLU B N     1 
ATOM   2580  C  CA    . GLU B 1 112 ? 225.502 234.408 183.026 1.00 25.18  ? 112 GLU B CA    1 
ATOM   2581  C  C     . GLU B 1 112 ? 224.029 234.089 182.744 1.00 23.33  ? 112 GLU B C     1 
ATOM   2582  O  O     . GLU B 1 112 ? 223.156 234.405 183.547 1.00 22.26  ? 112 GLU B O     1 
ATOM   2583  C  CB    . GLU B 1 112 ? 225.902 235.706 182.319 1.00 28.88  ? 112 GLU B CB    1 
ATOM   2584  C  CG    . GLU B 1 112 ? 227.279 236.246 182.705 1.00 35.30  ? 112 GLU B CG    1 
ATOM   2585  C  CD    . GLU B 1 112 ? 228.460 235.326 182.405 1.00 42.05  ? 112 GLU B CD    1 
ATOM   2586  O  OE1   . GLU B 1 112 ? 229.417 235.328 183.216 1.00 45.16  ? 112 GLU B OE1   1 
ATOM   2587  O  OE2   . GLU B 1 112 ? 228.400 234.576 181.396 1.00 39.40  ? 112 GLU B OE2   1 
ATOM   2588  N  N     . ASP B 1 113 ? 223.751 233.470 181.599 1.00 22.29  ? 113 ASP B N     1 
ATOM   2589  C  CA    . ASP B 1 113 ? 222.389 233.100 181.255 1.00 22.03  ? 113 ASP B CA    1 
ATOM   2590  C  C     . ASP B 1 113 ? 221.845 232.079 182.247 1.00 19.40  ? 113 ASP B C     1 
ATOM   2591  O  O     . ASP B 1 113 ? 220.699 232.183 182.683 1.00 19.76  ? 113 ASP B O     1 
ATOM   2592  C  CB    . ASP B 1 113 ? 222.296 232.559 179.840 1.00 25.66  ? 113 ASP B CB    1 
ATOM   2593  C  CG    . ASP B 1 113 ? 222.135 233.640 178.782 1.00 29.93  ? 113 ASP B CG    1 
ATOM   2594  O  OD1   . ASP B 1 113 ? 222.089 234.830 179.168 1.00 31.93  ? 113 ASP B OD1   1 
ATOM   2595  O  OD2   . ASP B 1 113 ? 222.054 233.281 177.589 1.00 33.81  ? 113 ASP B OD2   1 
ATOM   2596  N  N     . PHE B 1 114 ? 222.671 231.092 182.609 1.00 17.28  ? 114 PHE B N     1 
ATOM   2597  C  CA    . PHE B 1 114 ? 222.261 230.094 183.580 1.00 16.33  ? 114 PHE B CA    1 
ATOM   2598  C  C     . PHE B 1 114 ? 221.986 230.747 184.933 1.00 16.76  ? 114 PHE B C     1 
ATOM   2599  O  O     . PHE B 1 114 ? 221.002 230.413 185.601 1.00 17.07  ? 114 PHE B O     1 
ATOM   2600  C  CB    . PHE B 1 114 ? 223.342 229.027 183.697 1.00 15.77  ? 114 PHE B CB    1 
ATOM   2601  C  CG    . PHE B 1 114 ? 222.903 227.807 184.481 1.00 15.50  ? 114 PHE B CG    1 
ATOM   2602  C  CD1   . PHE B 1 114 ? 222.229 226.782 183.837 1.00 15.81  ? 114 PHE B CD1   1 
ATOM   2603  C  CD2   . PHE B 1 114 ? 223.187 227.678 185.828 1.00 15.73  ? 114 PHE B CD2   1 
ATOM   2604  C  CE1   . PHE B 1 114 ? 221.850 225.643 184.518 1.00 15.14  ? 114 PHE B CE1   1 
ATOM   2605  C  CE2   . PHE B 1 114 ? 222.800 226.539 186.515 1.00 15.98  ? 114 PHE B CE2   1 
ATOM   2606  C  CZ    . PHE B 1 114 ? 222.134 225.527 185.858 1.00 15.62  ? 114 PHE B CZ    1 
ATOM   2607  N  N     . GLN B 1 115 ? 222.870 231.664 185.348 1.00 18.45  ? 115 GLN B N     1 
ATOM   2608  C  CA    . GLN B 1 115 ? 222.742 232.307 186.646 1.00 19.77  ? 115 GLN B CA    1 
ATOM   2609  C  C     . GLN B 1 115 ? 221.477 233.157 186.692 1.00 19.45  ? 115 GLN B C     1 
ATOM   2610  O  O     . GLN B 1 115 ? 220.769 233.164 187.698 1.00 17.69  ? 115 GLN B O     1 
ATOM   2611  C  CB    . GLN B 1 115 ? 223.972 233.159 186.942 1.00 21.92  ? 115 GLN B CB    1 
ATOM   2612  C  CG    . GLN B 1 115 ? 223.980 233.758 188.340 1.00 26.53  ? 115 GLN B CG    1 
ATOM   2613  C  CD    . GLN B 1 115 ? 224.181 232.700 189.406 1.00 30.88  ? 115 GLN B CD    1 
ATOM   2614  O  OE1   . GLN B 1 115 ? 225.245 232.073 189.499 1.00 31.40  ? 115 GLN B OE1   1 
ATOM   2615  N  NE2   . GLN B 1 115 ? 223.174 232.490 190.242 1.00 31.60  ? 115 GLN B NE2   1 
ATOM   2616  N  N     . ARG B 1 116 ? 221.191 233.905 185.622 1.00 20.12  ? 116 ARG B N     1 
ATOM   2617  C  CA    . ARG B 1 116 ? 220.053 234.811 185.610 1.00 21.02  ? 116 ARG B CA    1 
ATOM   2618  C  C     . ARG B 1 116 ? 218.745 234.030 185.764 1.00 18.62  ? 116 ARG B C     1 
ATOM   2619  O  O     . ARG B 1 116 ? 217.847 234.456 186.461 1.00 19.06  ? 116 ARG B O     1 
ATOM   2620  C  CB    . ARG B 1 116 ? 220.074 235.652 184.331 1.00 24.22  ? 116 ARG B CB    1 
ATOM   2621  C  CG    . ARG B 1 116 ? 218.863 236.548 184.155 1.00 30.79  ? 116 ARG B CG    1 
ATOM   2622  C  CD    . ARG B 1 116 ? 218.942 237.410 182.906 1.00 35.90  ? 116 ARG B CD    1 
ATOM   2623  N  NE    . ARG B 1 116 ? 218.429 236.698 181.730 1.00 37.81  ? 116 ARG B NE    1 
ATOM   2624  C  CZ    . ARG B 1 116 ? 219.165 236.099 180.800 1.00 39.00  ? 116 ARG B CZ    1 
ATOM   2625  N  NH1   . ARG B 1 116 ? 220.487 236.072 180.879 1.00 37.98  ? 116 ARG B NH1   1 
ATOM   2626  N  NH2   . ARG B 1 116 ? 218.559 235.526 179.771 1.00 40.28  ? 116 ARG B NH2   1 
ATOM   2627  N  N     . VAL B 1 117 ? 218.620 232.909 185.065 1.00 16.45  ? 117 VAL B N     1 
ATOM   2628  C  CA    . VAL B 1 117 ? 217.426 232.086 185.167 1.00 15.57  ? 117 VAL B CA    1 
ATOM   2629  C  C     . VAL B 1 117 ? 217.300 231.488 186.568 1.00 14.92  ? 117 VAL B C     1 
ATOM   2630  O  O     . VAL B 1 117 ? 216.221 231.478 187.147 1.00 14.29  ? 117 VAL B O     1 
ATOM   2631  C  CB    . VAL B 1 117 ? 217.415 231.000 184.083 1.00 15.55  ? 117 VAL B CB    1 
ATOM   2632  C  CG1   . VAL B 1 117 ? 216.285 230.005 184.290 1.00 15.60  ? 117 VAL B CG1   1 
ATOM   2633  C  CG2   . VAL B 1 117 ? 217.342 231.629 182.705 1.00 16.44  ? 117 VAL B CG2   1 
ATOM   2634  N  N     . LEU B 1 118 ? 218.415 231.002 187.124 1.00 15.55  ? 118 LEU B N     1 
ATOM   2635  C  CA    . LEU B 1 118 ? 218.410 230.469 188.475 1.00 16.80  ? 118 LEU B CA    1 
ATOM   2636  C  C     . LEU B 1 118 ? 217.990 231.525 189.495 1.00 16.43  ? 118 LEU B C     1 
ATOM   2637  O  O     . LEU B 1 118 ? 217.231 231.243 190.417 1.00 15.99  ? 118 LEU B O     1 
ATOM   2638  C  CB    . LEU B 1 118 ? 219.787 229.908 188.830 1.00 18.39  ? 118 LEU B CB    1 
ATOM   2639  C  CG    . LEU B 1 118 ? 220.056 228.441 188.508 1.00 20.66  ? 118 LEU B CG    1 
ATOM   2640  C  CD1   . LEU B 1 118 ? 221.360 228.060 189.224 1.00 22.54  ? 118 LEU B CD1   1 
ATOM   2641  C  CD2   . LEU B 1 118 ? 218.928 227.534 188.955 1.00 21.83  ? 118 LEU B CD2   1 
ATOM   2642  N  N     . ASP B 1 119 ? 218.521 232.741 189.354 1.00 17.40  ? 119 ASP B N     1 
ATOM   2643  C  CA    . ASP B 1 119 ? 218.263 233.801 190.312 1.00 18.51  ? 119 ASP B CA    1 
ATOM   2644  C  C     . ASP B 1 119 ? 216.777 234.134 190.383 1.00 16.46  ? 119 ASP B C     1 
ATOM   2645  O  O     . ASP B 1 119 ? 216.229 234.292 191.471 1.00 18.19  ? 119 ASP B O     1 
ATOM   2646  C  CB    . ASP B 1 119 ? 219.088 235.031 189.981 1.00 21.45  ? 119 ASP B CB    1 
ATOM   2647  C  CG    . ASP B 1 119 ? 220.561 234.854 190.288 1.00 26.91  ? 119 ASP B CG    1 
ATOM   2648  O  OD1   . ASP B 1 119 ? 221.384 235.633 189.748 1.00 32.06  ? 119 ASP B OD1   1 
ATOM   2649  O  OD2   . ASP B 1 119 ? 220.889 233.979 191.139 1.00 30.02  ? 119 ASP B OD2   1 
ATOM   2650  N  N     . VAL B 1 120 ? 216.132 234.271 189.227 1.00 14.88  ? 120 VAL B N     1 
ATOM   2651  C  CA    . VAL B 1 120 ? 214.738 234.675 189.205 1.00 14.53  ? 120 VAL B CA    1 
ATOM   2652  C  C     . VAL B 1 120 ? 213.836 233.494 189.559 1.00 13.60  ? 120 VAL B C     1 
ATOM   2653  O  O     . VAL B 1 120 ? 212.985 233.599 190.437 1.00 14.21  ? 120 VAL B O     1 
ATOM   2654  C  CB    . VAL B 1 120 ? 214.370 235.292 187.846 1.00 16.33  ? 120 VAL B CB    1 
ATOM   2655  C  CG1   . VAL B 1 120 ? 212.875 235.536 187.731 1.00 16.23  ? 120 VAL B CG1   1 
ATOM   2656  C  CG2   . VAL B 1 120 ? 215.135 236.585 187.613 1.00 16.80  ? 120 VAL B CG2   1 
ATOM   2657  N  N     . ASN B 1 121 ? 214.001 232.374 188.857 1.00 12.62  ? 121 ASN B N     1 
ATOM   2658  C  CA    . ASN B 1 121 ? 213.083 231.258 188.990 1.00 13.00  ? 121 ASN B CA    1 
ATOM   2659  C  C     . ASN B 1 121 ? 213.226 230.580 190.347 1.00 12.25  ? 121 ASN B C     1 
ATOM   2660  O  O     . ASN B 1 121 ? 212.233 230.312 191.021 1.00 13.79  ? 121 ASN B O     1 
ATOM   2661  C  CB    . ASN B 1 121 ? 213.269 230.262 187.861 1.00 13.10  ? 121 ASN B CB    1 
ATOM   2662  C  CG    . ASN B 1 121 ? 212.909 230.842 186.512 1.00 14.23  ? 121 ASN B CG    1 
ATOM   2663  O  OD1   . ASN B 1 121 ? 212.668 232.047 186.393 1.00 14.75  ? 121 ASN B OD1   1 
ATOM   2664  N  ND2   . ASN B 1 121 ? 212.933 230.011 185.479 1.00 14.93  ? 121 ASN B ND2   1 
ATOM   2665  N  N     . LEU B 1 122 ? 214.469 230.288 190.749 1.00 11.58  ? 122 LEU B N     1 
ATOM   2666  C  CA    . LEU B 1 122 ? 214.719 229.433 191.901 1.00 11.00  ? 122 LEU B CA    1 
ATOM   2667  C  C     . LEU B 1 122 ? 215.009 230.276 193.139 1.00 11.57  ? 122 LEU B C     1 
ATOM   2668  O  O     . LEU B 1 122 ? 214.324 230.156 194.150 1.00 10.90  ? 122 LEU B O     1 
ATOM   2669  C  CB    . LEU B 1 122 ? 215.857 228.453 191.604 1.00 10.40  ? 122 LEU B CB    1 
ATOM   2670  C  CG    . LEU B 1 122 ? 216.224 227.492 192.736 1.00 10.25  ? 122 LEU B CG    1 
ATOM   2671  C  CD1   . LEU B 1 122 ? 214.999 226.789 193.274 1.00 10.07  ? 122 LEU B CD1   1 
ATOM   2672  C  CD2   . LEU B 1 122 ? 217.268 226.495 192.242 1.00 10.24  ? 122 LEU B CD2   1 
ATOM   2673  N  N     . MET B 1 123 ? 216.034 231.115 193.065 1.00 12.66  ? 123 MET B N     1 
ATOM   2674  C  CA    . MET B 1 123 ? 216.404 231.953 194.194 1.00 15.15  ? 123 MET B CA    1 
ATOM   2675  C  C     . MET B 1 123 ? 215.281 232.937 194.518 1.00 12.60  ? 123 MET B C     1 
ATOM   2676  O  O     . MET B 1 123 ? 214.985 233.179 195.684 1.00 12.02  ? 123 MET B O     1 
ATOM   2677  C  CB    . MET B 1 123 ? 217.723 232.685 193.905 1.00 17.86  ? 123 MET B CB    1 
ATOM   2678  C  CG    . MET B 1 123 ? 218.293 233.412 195.098 1.00 22.33  ? 123 MET B CG    1 
ATOM   2679  S  SD    . MET B 1 123 ? 217.666 235.096 195.267 1.00 29.07  ? 123 MET B SD    1 
ATOM   2680  C  CE    . MET B 1 123 ? 218.539 235.901 193.919 1.00 27.56  ? 123 MET B CE    1 
ATOM   2681  N  N     . GLY B 1 124 ? 214.646 233.501 193.490 1.00 11.83  ? 124 GLY B N     1 
ATOM   2682  C  CA    . GLY B 1 124 ? 213.547 234.424 193.707 1.00 11.75  ? 124 GLY B CA    1 
ATOM   2683  C  C     . GLY B 1 124 ? 212.368 233.749 194.409 1.00 11.52  ? 124 GLY B C     1 
ATOM   2684  O  O     . GLY B 1 124 ? 211.752 234.321 195.298 1.00 11.93  ? 124 GLY B O     1 
ATOM   2685  N  N     . THR B 1 125 ? 212.059 232.512 194.005 1.00 10.78  ? 125 THR B N     1 
ATOM   2686  C  CA    . THR B 1 125 ? 210.989 231.760 194.644 1.00 10.12  ? 125 THR B CA    1 
ATOM   2687  C  C     . THR B 1 125 ? 211.304 231.539 196.123 1.00 9.18   ? 125 THR B C     1 
ATOM   2688  O  O     . THR B 1 125 ? 210.453 231.739 196.979 1.00 8.95   ? 125 THR B O     1 
ATOM   2689  C  CB    . THR B 1 125 ? 210.756 230.435 193.922 1.00 10.50  ? 125 THR B CB    1 
ATOM   2690  O  OG1   . THR B 1 125 ? 210.095 230.701 192.692 1.00 10.91  ? 125 THR B OG1   1 
ATOM   2691  C  CG2   . THR B 1 125 ? 209.904 229.497 194.752 1.00 10.33  ? 125 THR B CG2   1 
ATOM   2692  N  N     . PHE B 1 126 ? 212.522 231.091 196.427 1.00 9.02   ? 126 PHE B N     1 
ATOM   2693  C  CA    . PHE B 1 126 ? 212.904 230.837 197.808 1.00 8.94   ? 126 PHE B CA    1 
ATOM   2694  C  C     . PHE B 1 126 ? 212.903 232.135 198.616 1.00 8.62   ? 126 PHE B C     1 
ATOM   2695  O  O     . PHE B 1 126 ? 212.533 232.138 199.784 1.00 8.31   ? 126 PHE B O     1 
ATOM   2696  C  CB    . PHE B 1 126 ? 214.279 230.153 197.875 1.00 8.99   ? 126 PHE B CB    1 
ATOM   2697  C  CG    . PHE B 1 126 ? 214.677 229.823 199.301 1.00 9.65   ? 126 PHE B CG    1 
ATOM   2698  C  CD1   . PHE B 1 126 ? 214.087 228.757 199.974 1.00 10.08  ? 126 PHE B CD1   1 
ATOM   2699  C  CD2   . PHE B 1 126 ? 215.604 230.601 199.968 1.00 9.40   ? 126 PHE B CD2   1 
ATOM   2700  C  CE1   . PHE B 1 126 ? 214.431 228.482 201.287 1.00 10.42  ? 126 PHE B CE1   1 
ATOM   2701  C  CE2   . PHE B 1 126 ? 215.956 230.310 201.274 1.00 9.71   ? 126 PHE B CE2   1 
ATOM   2702  C  CZ    . PHE B 1 126 ? 215.362 229.259 201.934 1.00 10.32  ? 126 PHE B CZ    1 
ATOM   2703  N  N     . ASN B 1 127 ? 213.340 233.227 198.001 1.00 9.17   ? 127 ASN B N     1 
ATOM   2704  C  CA    . ASN B 1 127 ? 213.363 234.521 198.670 1.00 9.91   ? 127 ASN B CA    1 
ATOM   2705  C  C     . ASN B 1 127 ? 211.953 234.928 199.092 1.00 9.62   ? 127 ASN B C     1 
ATOM   2706  O  O     . ASN B 1 127 ? 211.748 235.414 200.197 1.00 9.97   ? 127 ASN B O     1 
ATOM   2707  C  CB    . ASN B 1 127 ? 214.009 235.570 197.778 1.00 10.58  ? 127 ASN B CB    1 
ATOM   2708  C  CG    . ASN B 1 127 ? 214.128 236.910 198.456 1.00 11.60  ? 127 ASN B CG    1 
ATOM   2709  O  OD1   . ASN B 1 127 ? 214.489 236.968 199.635 1.00 12.70  ? 127 ASN B OD1   1 
ATOM   2710  N  ND2   . ASN B 1 127 ? 213.813 237.992 197.750 1.00 12.86  ? 127 ASN B ND2   1 
ATOM   2711  N  N     . VAL B 1 128 ? 210.976 234.734 198.214 1.00 9.36   ? 128 VAL B N     1 
ATOM   2712  C  CA    . VAL B 1 128 ? 209.594 235.019 198.562 1.00 9.44   ? 128 VAL B CA    1 
ATOM   2713  C  C     . VAL B 1 128 ? 209.122 234.058 199.647 1.00 9.20   ? 128 VAL B C     1 
ATOM   2714  O  O     . VAL B 1 128 ? 208.486 234.481 200.608 1.00 9.69   ? 128 VAL B O     1 
ATOM   2715  C  CB    . VAL B 1 128 ? 208.698 234.962 197.314 1.00 10.02  ? 128 VAL B CB    1 
ATOM   2716  C  CG1   . VAL B 1 128 ? 207.221 235.072 197.666 1.00 10.46  ? 128 VAL B CG1   1 
ATOM   2717  C  CG2   . VAL B 1 128 ? 209.087 236.057 196.338 1.00 9.99   ? 128 VAL B CG2   1 
ATOM   2718  N  N     . ILE B 1 129 ? 209.430 232.762 199.499 1.00 8.54   ? 129 ILE B N     1 
ATOM   2719  C  CA    . ILE B 1 129 ? 208.946 231.763 200.438 1.00 8.41   ? 129 ILE B CA    1 
ATOM   2720  C  C     . ILE B 1 129 ? 209.429 232.088 201.845 1.00 8.38   ? 129 ILE B C     1 
ATOM   2721  O  O     . ILE B 1 129 ? 208.649 232.080 202.794 1.00 9.04   ? 129 ILE B O     1 
ATOM   2722  C  CB    . ILE B 1 129 ? 209.374 230.344 200.015 1.00 8.26   ? 129 ILE B CB    1 
ATOM   2723  C  CG1   . ILE B 1 129 ? 208.551 229.861 198.819 1.00 8.32   ? 129 ILE B CG1   1 
ATOM   2724  C  CG2   . ILE B 1 129 ? 209.257 229.383 201.195 1.00 8.13   ? 129 ILE B CG2   1 
ATOM   2725  C  CD1   . ILE B 1 129 ? 209.073 228.586 198.207 1.00 8.59   ? 129 ILE B CD1   1 
ATOM   2726  N  N     . ARG B 1 130 ? 210.731 232.333 201.998 1.00 8.58   ? 130 ARG B N     1 
ATOM   2727  C  CA    . ARG B 1 130 ? 211.308 232.503 203.324 1.00 9.30   ? 130 ARG B CA    1 
ATOM   2728  C  C     . ARG B 1 130 ? 210.775 233.769 204.002 1.00 9.28   ? 130 ARG B C     1 
ATOM   2729  O  O     . ARG B 1 130 ? 210.712 233.808 205.220 1.00 9.53   ? 130 ARG B O     1 
ATOM   2730  C  CB    . ARG B 1 130 ? 212.837 232.530 203.256 1.00 9.76   ? 130 ARG B CB    1 
ATOM   2731  C  CG    . ARG B 1 130 ? 213.411 233.889 202.888 1.00 10.02  ? 130 ARG B CG    1 
ATOM   2732  C  CD    . ARG B 1 130 ? 214.821 233.765 202.351 1.00 10.32  ? 130 ARG B CD    1 
ATOM   2733  N  NE    . ARG B 1 130 ? 215.297 235.082 201.928 1.00 10.83  ? 130 ARG B NE    1 
ATOM   2734  C  CZ    . ARG B 1 130 ? 215.711 236.032 202.740 1.00 11.14  ? 130 ARG B CZ    1 
ATOM   2735  N  NH1   . ARG B 1 130 ? 215.886 235.791 204.022 1.00 11.22  ? 130 ARG B NH1   1 
ATOM   2736  N  NH2   . ARG B 1 130 ? 215.975 237.227 202.254 1.00 11.67  ? 130 ARG B NH2   1 
ATOM   2737  N  N     . LEU B 1 131 ? 210.405 234.789 203.224 1.00 9.33   ? 131 LEU B N     1 
ATOM   2738  C  CA    . LEU B 1 131 ? 209.930 236.045 203.789 1.00 10.08  ? 131 LEU B CA    1 
ATOM   2739  C  C     . LEU B 1 131 ? 208.424 236.020 204.043 1.00 10.80  ? 131 LEU B C     1 
ATOM   2740  O  O     . LEU B 1 131 ? 207.970 236.536 205.059 1.00 11.08  ? 131 LEU B O     1 
ATOM   2741  C  CB    . LEU B 1 131 ? 210.294 237.210 202.878 1.00 10.20  ? 131 LEU B CB    1 
ATOM   2742  C  CG    . LEU B 1 131 ? 211.793 237.519 202.790 1.00 10.58  ? 131 LEU B CG    1 
ATOM   2743  C  CD1   . LEU B 1 131 ? 212.060 238.540 201.703 1.00 10.70  ? 131 LEU B CD1   1 
ATOM   2744  C  CD2   . LEU B 1 131 ? 212.341 237.985 204.124 1.00 10.62  ? 131 LEU B CD2   1 
ATOM   2745  N  N     . VAL B 1 132 ? 207.643 235.423 203.139 1.00 11.43  ? 132 VAL B N     1 
ATOM   2746  C  CA    . VAL B 1 132 ? 206.210 235.333 203.353 1.00 13.06  ? 132 VAL B CA    1 
ATOM   2747  C  C     . VAL B 1 132 ? 205.892 234.361 204.489 1.00 12.40  ? 132 VAL B C     1 
ATOM   2748  O  O     . VAL B 1 132 ? 204.908 234.552 205.199 1.00 12.84  ? 132 VAL B O     1 
ATOM   2749  C  CB    . VAL B 1 132 ? 205.462 234.936 202.068 1.00 15.36  ? 132 VAL B CB    1 
ATOM   2750  C  CG1   . VAL B 1 132 ? 203.963 234.954 202.295 1.00 16.58  ? 132 VAL B CG1   1 
ATOM   2751  C  CG2   . VAL B 1 132 ? 205.760 235.884 200.924 1.00 17.81  ? 132 VAL B CG2   1 
ATOM   2752  N  N     . ALA B 1 133 ? 206.746 233.354 204.691 1.00 12.55  ? 133 ALA B N     1 
ATOM   2753  C  CA    . ALA B 1 133 ? 206.574 232.424 205.795 1.00 13.31  ? 133 ALA B CA    1 
ATOM   2754  C  C     . ALA B 1 133 ? 206.609 233.165 207.130 1.00 14.38  ? 133 ALA B C     1 
ATOM   2755  O  O     . ALA B 1 133 ? 205.831 232.860 208.029 1.00 14.51  ? 133 ALA B O     1 
ATOM   2756  C  CB    . ALA B 1 133 ? 207.611 231.320 205.758 1.00 13.65  ? 133 ALA B CB    1 
ATOM   2757  N  N     . GLY B 1 134 ? 207.522 234.126 207.267 1.00 15.37  ? 134 GLY B N     1 
ATOM   2758  C  CA    . GLY B 1 134 ? 207.555 234.970 208.449 1.00 16.00  ? 134 GLY B CA    1 
ATOM   2759  C  C     . GLY B 1 134 ? 206.273 235.784 208.599 1.00 16.90  ? 134 GLY B C     1 
ATOM   2760  O  O     . GLY B 1 134 ? 205.786 235.951 209.713 1.00 17.72  ? 134 GLY B O     1 
ATOM   2761  N  N     . GLU B 1 135 ? 205.725 236.286 207.480 1.00 16.98  ? 135 GLU B N     1 
ATOM   2762  C  CA    . GLU B 1 135 ? 204.475 237.021 207.525 1.00 18.15  ? 135 GLU B CA    1 
ATOM   2763  C  C     . GLU B 1 135 ? 203.325 236.099 207.926 1.00 16.14  ? 135 GLU B C     1 
ATOM   2764  O  O     . GLU B 1 135 ? 202.502 236.459 208.764 1.00 16.67  ? 135 GLU B O     1 
ATOM   2765  C  CB    . GLU B 1 135 ? 204.178 237.678 206.180 1.00 22.25  ? 135 GLU B CB    1 
ATOM   2766  C  CG    . GLU B 1 135 ? 205.154 238.790 205.835 1.00 27.99  ? 135 GLU B CG    1 
ATOM   2767  C  CD    . GLU B 1 135 ? 205.325 239.819 206.934 1.00 33.27  ? 135 GLU B CD    1 
ATOM   2768  O  OE1   . GLU B 1 135 ? 204.304 240.257 207.522 1.00 37.40  ? 135 GLU B OE1   1 
ATOM   2769  O  OE2   . GLU B 1 135 ? 206.490 240.191 207.192 1.00 35.95  ? 135 GLU B OE2   1 
ATOM   2770  N  N     . MET B 1 136 ? 203.248 234.912 207.315 1.00 15.00  ? 136 MET B N     1 
ATOM   2771  C  CA    . MET B 1 136 ? 202.169 233.990 207.625 1.00 13.69  ? 136 MET B CA    1 
ATOM   2772  C  C     . MET B 1 136 ? 202.329 233.436 209.039 1.00 14.14  ? 136 MET B C     1 
ATOM   2773  O  O     . MET B 1 136 ? 201.343 233.085 209.678 1.00 14.25  ? 136 MET B O     1 
ATOM   2774  C  CB    . MET B 1 136 ? 202.122 232.824 206.632 1.00 13.45  ? 136 MET B CB    1 
ATOM   2775  C  CG    . MET B 1 136 ? 201.912 233.225 205.193 1.00 12.83  ? 136 MET B CG    1 
ATOM   2776  S  SD    . MET B 1 136 ? 202.227 231.820 204.100 1.00 12.18  ? 136 MET B SD    1 
ATOM   2777  C  CE    . MET B 1 136 ? 201.463 232.430 202.591 1.00 11.79  ? 136 MET B CE    1 
ATOM   2778  N  N     . GLY B 1 137 ? 203.565 233.347 209.538 1.00 15.30  ? 137 GLY B N     1 
ATOM   2779  C  CA    . GLY B 1 137 ? 203.809 232.888 210.898 1.00 16.97  ? 137 GLY B CA    1 
ATOM   2780  C  C     . GLY B 1 137 ? 203.122 233.761 211.945 1.00 18.63  ? 137 GLY B C     1 
ATOM   2781  O  O     . GLY B 1 137 ? 202.853 233.295 213.043 1.00 19.58  ? 137 GLY B O     1 
ATOM   2782  N  N     . GLN B 1 138 ? 202.859 235.025 211.616 1.00 20.99  ? 138 GLN B N     1 
ATOM   2783  C  CA    . GLN B 1 138 ? 202.191 235.927 212.542 1.00 23.87  ? 138 GLN B CA    1 
ATOM   2784  C  C     . GLN B 1 138 ? 200.687 235.683 212.588 1.00 23.09  ? 138 GLN B C     1 
ATOM   2785  O  O     . GLN B 1 138 ? 200.026 236.174 213.494 1.00 25.46  ? 138 GLN B O     1 
ATOM   2786  C  CB    . GLN B 1 138 ? 202.457 237.383 212.174 1.00 29.34  ? 138 GLN B CB    1 
ATOM   2787  C  CG    . GLN B 1 138 ? 203.925 237.788 212.292 1.00 34.79  ? 138 GLN B CG    1 
ATOM   2788  C  CD    . GLN B 1 138 ? 204.455 237.639 213.706 1.00 44.30  ? 138 GLN B CD    1 
ATOM   2789  O  OE1   . GLN B 1 138 ? 203.765 237.994 214.670 1.00 48.70  ? 138 GLN B OE1   1 
ATOM   2790  N  NE2   . GLN B 1 138 ? 205.675 237.124 213.865 1.00 47.91  ? 138 GLN B NE2   1 
ATOM   2791  N  N     . ASN B 1 139 ? 200.135 234.941 211.625 1.00 21.67  ? 139 ASN B N     1 
ATOM   2792  C  CA    . ASN B 1 139 ? 198.712 234.640 211.618 1.00 19.99  ? 139 ASN B CA    1 
ATOM   2793  C  C     . ASN B 1 139 ? 198.376 233.713 212.779 1.00 21.22  ? 139 ASN B C     1 
ATOM   2794  O  O     . ASN B 1 139 ? 199.124 232.790 213.092 1.00 19.81  ? 139 ASN B O     1 
ATOM   2795  C  CB    . ASN B 1 139 ? 198.276 234.015 210.296 1.00 18.48  ? 139 ASN B CB    1 
ATOM   2796  C  CG    . ASN B 1 139 ? 198.365 234.977 209.142 1.00 17.87  ? 139 ASN B CG    1 
ATOM   2797  O  OD1   . ASN B 1 139 ? 198.359 236.196 209.348 1.00 20.40  ? 139 ASN B OD1   1 
ATOM   2798  N  ND2   . ASN B 1 139 ? 198.447 234.461 207.924 1.00 17.35  ? 139 ASN B ND2   1 
ATOM   2799  N  N     . GLU B 1 140 ? 197.209 233.934 213.375 1.00 23.08  ? 140 GLU B N     1 
ATOM   2800  C  CA    . GLU B 1 140 ? 196.662 232.974 214.316 1.00 25.93  ? 140 GLU B CA    1 
ATOM   2801  C  C     . GLU B 1 140 ? 196.192 231.769 213.510 1.00 23.85  ? 140 GLU B C     1 
ATOM   2802  O  O     . GLU B 1 140 ? 195.531 231.929 212.481 1.00 23.85  ? 140 GLU B O     1 
ATOM   2803  C  CB    . GLU B 1 140 ? 195.489 233.563 215.095 1.00 31.21  ? 140 GLU B CB    1 
ATOM   2804  C  CG    . GLU B 1 140 ? 195.867 234.802 215.898 1.00 38.01  ? 140 GLU B CG    1 
ATOM   2805  C  CD    . GLU B 1 140 ? 196.747 234.555 217.108 1.00 46.02  ? 140 GLU B CD    1 
ATOM   2806  O  OE1   . GLU B 1 140 ? 197.126 233.398 217.376 1.00 48.51  ? 140 GLU B OE1   1 
ATOM   2807  O  OE2   . GLU B 1 140 ? 197.058 235.562 217.785 1.00 53.85  ? 140 GLU B OE2   1 
ATOM   2808  N  N     . PRO B 1 141 ? 196.508 230.527 213.927 1.00 22.14  ? 141 PRO B N     1 
ATOM   2809  C  CA    . PRO B 1 141 ? 196.041 229.355 213.193 1.00 23.67  ? 141 PRO B CA    1 
ATOM   2810  C  C     . PRO B 1 141 ? 194.520 229.320 213.105 1.00 24.31  ? 141 PRO B C     1 
ATOM   2811  O  O     . PRO B 1 141 ? 193.831 229.690 214.058 1.00 26.18  ? 141 PRO B O     1 
ATOM   2812  C  CB    . PRO B 1 141 ? 196.592 228.171 213.988 1.00 22.51  ? 141 PRO B CB    1 
ATOM   2813  C  CG    . PRO B 1 141 ? 197.701 228.759 214.826 1.00 23.23  ? 141 PRO B CG    1 
ATOM   2814  C  CD    . PRO B 1 141 ? 197.303 230.185 215.110 1.00 22.03  ? 141 PRO B CD    1 
ATOM   2815  N  N     . ASP B 1 142 ? 194.006 228.868 211.958 1.00 26.29  ? 142 ASP B N     1 
ATOM   2816  C  CA    . ASP B 1 142 ? 192.573 228.751 211.756 1.00 26.95  ? 142 ASP B CA    1 
ATOM   2817  C  C     . ASP B 1 142 ? 192.072 227.503 212.482 1.00 27.66  ? 142 ASP B C     1 
ATOM   2818  O  O     . ASP B 1 142 ? 192.798 226.888 213.260 1.00 26.42  ? 142 ASP B O     1 
ATOM   2819  C  CB    . ASP B 1 142 ? 192.259 228.756 210.268 1.00 28.05  ? 142 ASP B CB    1 
ATOM   2820  C  CG    . ASP B 1 142 ? 192.775 227.546 209.501 1.00 29.58  ? 142 ASP B CG    1 
ATOM   2821  O  OD1   . ASP B 1 142 ? 193.414 226.677 210.135 1.00 28.03  ? 142 ASP B OD1   1 
ATOM   2822  O  OD2   . ASP B 1 142 ? 192.560 227.502 208.275 1.00 31.55  ? 142 ASP B OD2   1 
ATOM   2823  N  N     . GLN B 1 143 ? 190.819 227.110 212.214 1.00 32.09  ? 143 GLN B N     1 
ATOM   2824  C  CA    . GLN B 1 143 ? 190.221 225.972 212.894 1.00 37.16  ? 143 GLN B CA    1 
ATOM   2825  C  C     . GLN B 1 143 ? 191.015 224.696 212.618 1.00 34.17  ? 143 GLN B C     1 
ATOM   2826  O  O     . GLN B 1 143 ? 191.049 223.803 213.462 1.00 36.25  ? 143 GLN B O     1 
ATOM   2827  C  CB    . GLN B 1 143 ? 188.752 225.819 212.491 1.00 46.72  ? 143 GLN B CB    1 
ATOM   2828  C  CG    . GLN B 1 143 ? 188.501 225.224 211.106 1.00 55.60  ? 143 GLN B CG    1 
ATOM   2829  C  CD    . GLN B 1 143 ? 188.930 226.122 209.965 1.00 63.87  ? 143 GLN B CD    1 
ATOM   2830  O  OE1   . GLN B 1 143 ? 189.039 227.341 210.133 1.00 65.83  ? 143 GLN B OE1   1 
ATOM   2831  N  NE2   . GLN B 1 143 ? 189.172 225.537 208.799 1.00 68.13  ? 143 GLN B NE2   1 
ATOM   2832  N  N     . GLY B 1 144 ? 191.639 224.605 211.438 1.00 29.57  ? 144 GLY B N     1 
ATOM   2833  C  CA    . GLY B 1 144 ? 192.425 223.435 211.083 1.00 26.26  ? 144 GLY B CA    1 
ATOM   2834  C  C     . GLY B 1 144 ? 193.902 223.560 211.454 1.00 24.02  ? 144 GLY B C     1 
ATOM   2835  O  O     . GLY B 1 144 ? 194.699 222.689 211.105 1.00 24.44  ? 144 GLY B O     1 
ATOM   2836  N  N     . GLY B 1 145 ? 194.284 224.645 212.134 1.00 19.89  ? 145 GLY B N     1 
ATOM   2837  C  CA    . GLY B 1 145 ? 195.672 224.841 212.523 1.00 17.42  ? 145 GLY B CA    1 
ATOM   2838  C  C     . GLY B 1 145 ? 196.534 225.441 211.411 1.00 16.07  ? 145 GLY B C     1 
ATOM   2839  O  O     . GLY B 1 145 ? 197.752 225.494 211.552 1.00 17.66  ? 145 GLY B O     1 
ATOM   2840  N  N     . GLN B 1 146 ? 195.910 225.899 210.316 1.00 14.77  ? 146 GLN B N     1 
ATOM   2841  C  CA    . GLN B 1 146 ? 196.651 226.388 209.165 1.00 14.19  ? 146 GLN B CA    1 
ATOM   2842  C  C     . GLN B 1 146 ? 196.901 227.887 209.296 1.00 13.46  ? 146 GLN B C     1 
ATOM   2843  O  O     . GLN B 1 146 ? 195.994 228.644 209.625 1.00 13.75  ? 146 GLN B O     1 
ATOM   2844  C  CB    . GLN B 1 146 ? 195.875 226.081 207.888 1.00 13.43  ? 146 GLN B CB    1 
ATOM   2845  C  CG    . GLN B 1 146 ? 196.560 226.556 206.618 1.00 13.92  ? 146 GLN B CG    1 
ATOM   2846  C  CD    . GLN B 1 146 ? 195.784 226.190 205.378 1.00 14.61  ? 146 GLN B CD    1 
ATOM   2847  O  OE1   . GLN B 1 146 ? 195.842 225.054 204.898 1.00 16.19  ? 146 GLN B OE1   1 
ATOM   2848  N  NE2   . GLN B 1 146 ? 195.067 227.158 204.843 1.00 14.86  ? 146 GLN B NE2   1 
ATOM   2849  N  N     . ARG B 1 147 ? 198.129 228.310 209.004 1.00 12.92  ? 147 ARG B N     1 
ATOM   2850  C  CA    . ARG B 1 147 ? 198.478 229.723 208.992 1.00 12.81  ? 147 ARG B CA    1 
ATOM   2851  C  C     . ARG B 1 147 ? 198.616 230.270 207.574 1.00 12.10  ? 147 ARG B C     1 
ATOM   2852  O  O     . ARG B 1 147 ? 198.472 231.468 207.364 1.00 13.31  ? 147 ARG B O     1 
ATOM   2853  C  CB    . ARG B 1 147 ? 199.796 229.966 209.727 1.00 13.74  ? 147 ARG B CB    1 
ATOM   2854  C  CG    . ARG B 1 147 ? 199.662 229.963 211.237 1.00 14.42  ? 147 ARG B CG    1 
ATOM   2855  C  CD    . ARG B 1 147 ? 200.961 230.381 211.870 1.00 15.79  ? 147 ARG B CD    1 
ATOM   2856  N  NE    . ARG B 1 147 ? 200.869 230.446 213.333 1.00 16.70  ? 147 ARG B NE    1 
ATOM   2857  C  CZ    . ARG B 1 147 ? 201.053 229.432 214.155 1.00 18.52  ? 147 ARG B CZ    1 
ATOM   2858  N  NH1   . ARG B 1 147 ? 201.298 228.218 213.702 1.00 18.81  ? 147 ARG B NH1   1 
ATOM   2859  N  NH2   . ARG B 1 147 ? 200.980 229.635 215.458 1.00 19.59  ? 147 ARG B NH2   1 
ATOM   2860  N  N     . GLY B 1 148 ? 198.882 229.413 206.590 1.00 11.10  ? 148 GLY B N     1 
ATOM   2861  C  CA    . GLY B 1 148 ? 198.998 229.896 205.233 1.00 10.20  ? 148 GLY B CA    1 
ATOM   2862  C  C     . GLY B 1 148 ? 199.240 228.767 204.247 1.00 9.36   ? 148 GLY B C     1 
ATOM   2863  O  O     . GLY B 1 148 ? 199.465 227.626 204.634 1.00 8.61   ? 148 GLY B O     1 
ATOM   2864  N  N     . VAL B 1 149 ? 199.186 229.133 202.974 1.00 8.85   ? 149 VAL B N     1 
ATOM   2865  C  CA    . VAL B 1 149 ? 199.450 228.213 201.883 1.00 8.80   ? 149 VAL B CA    1 
ATOM   2866  C  C     . VAL B 1 149 ? 200.412 228.902 200.925 1.00 7.97   ? 149 VAL B C     1 
ATOM   2867  O  O     . VAL B 1 149 ? 200.189 230.047 200.536 1.00 7.88   ? 149 VAL B O     1 
ATOM   2868  C  CB    . VAL B 1 149 ? 198.168 227.794 201.132 1.00 9.24   ? 149 VAL B CB    1 
ATOM   2869  C  CG1   . VAL B 1 149 ? 198.461 226.689 200.127 1.00 9.30   ? 149 VAL B CG1   1 
ATOM   2870  C  CG2   . VAL B 1 149 ? 197.074 227.362 202.087 1.00 9.71   ? 149 VAL B CG2   1 
ATOM   2871  N  N     . ILE B 1 150 ? 201.484 228.189 200.568 1.00 7.66   ? 150 ILE B N     1 
ATOM   2872  C  CA    . ILE B 1 150 ? 202.423 228.664 199.571 1.00 8.05   ? 150 ILE B CA    1 
ATOM   2873  C  C     . ILE B 1 150 ? 202.362 227.736 198.361 1.00 7.96   ? 150 ILE B C     1 
ATOM   2874  O  O     . ILE B 1 150 ? 202.516 226.520 198.501 1.00 7.92   ? 150 ILE B O     1 
ATOM   2875  C  CB    . ILE B 1 150 ? 203.844 228.737 200.147 1.00 8.43   ? 150 ILE B CB    1 
ATOM   2876  C  CG1   . ILE B 1 150 ? 203.906 229.713 201.314 1.00 8.60   ? 150 ILE B CG1   1 
ATOM   2877  C  CG2   . ILE B 1 150 ? 204.851 229.095 199.055 1.00 8.48   ? 150 ILE B CG2   1 
ATOM   2878  C  CD1   . ILE B 1 150 ? 205.215 229.704 202.078 1.00 8.86   ? 150 ILE B CD1   1 
ATOM   2879  N  N     . ILE B 1 151 ? 202.132 228.332 197.188 1.00 8.16   ? 151 ILE B N     1 
ATOM   2880  C  CA    . ILE B 1 151 ? 202.043 227.590 195.947 1.00 8.65   ? 151 ILE B CA    1 
ATOM   2881  C  C     . ILE B 1 151 ? 203.124 228.098 195.004 1.00 9.03   ? 151 ILE B C     1 
ATOM   2882  O  O     . ILE B 1 151 ? 203.167 229.281 194.694 1.00 9.36   ? 151 ILE B O     1 
ATOM   2883  C  CB    . ILE B 1 151 ? 200.647 227.687 195.315 1.00 9.33   ? 151 ILE B CB    1 
ATOM   2884  C  CG1   . ILE B 1 151 ? 199.595 227.106 196.232 1.00 10.04  ? 151 ILE B CG1   1 
ATOM   2885  C  CG2   . ILE B 1 151 ? 200.629 227.009 193.946 1.00 9.71   ? 151 ILE B CG2   1 
ATOM   2886  C  CD1   . ILE B 1 151 ? 198.241 227.755 196.106 1.00 10.67  ? 151 ILE B CD1   1 
ATOM   2887  N  N     . ASN B 1 152 ? 203.983 227.180 194.557 1.00 9.05   ? 152 ASN B N     1 
ATOM   2888  C  CA    . ASN B 1 152 ? 205.081 227.505 193.662 1.00 9.80   ? 152 ASN B CA    1 
ATOM   2889  C  C     . ASN B 1 152 ? 204.756 227.017 192.258 1.00 10.25  ? 152 ASN B C     1 
ATOM   2890  O  O     . ASN B 1 152 ? 203.948 226.114 192.068 1.00 10.33  ? 152 ASN B O     1 
ATOM   2891  C  CB    . ASN B 1 152 ? 206.388 226.886 194.136 1.00 10.01  ? 152 ASN B CB    1 
ATOM   2892  C  CG    . ASN B 1 152 ? 206.591 227.078 195.617 1.00 10.29  ? 152 ASN B CG    1 
ATOM   2893  O  OD1   . ASN B 1 152 ? 206.641 228.216 196.090 1.00 10.81  ? 152 ASN B OD1   1 
ATOM   2894  N  ND2   . ASN B 1 152 ? 206.687 225.993 196.374 1.00 11.43  ? 152 ASN B ND2   1 
ATOM   2895  N  N     . THR B 1 153 ? 205.405 227.632 191.277 1.00 11.38  ? 153 THR B N     1 
ATOM   2896  C  CA    . THR B 1 153 ? 205.262 227.250 189.889 1.00 12.72  ? 153 THR B CA    1 
ATOM   2897  C  C     . THR B 1 153 ? 206.587 226.674 189.401 1.00 13.24  ? 153 THR B C     1 
ATOM   2898  O  O     . THR B 1 153 ? 207.531 227.408 189.131 1.00 15.15  ? 153 THR B O     1 
ATOM   2899  C  CB    . THR B 1 153 ? 204.822 228.437 189.037 1.00 13.09  ? 153 THR B CB    1 
ATOM   2900  O  OG1   . THR B 1 153 ? 203.668 229.035 189.616 1.00 14.51  ? 153 THR B OG1   1 
ATOM   2901  C  CG2   . THR B 1 153 ? 204.500 228.004 187.617 1.00 13.76  ? 153 THR B CG2   1 
ATOM   2902  N  N     . ALA B 1 154 ? 206.620 225.348 189.264 1.00 14.05  ? 154 ALA B N     1 
ATOM   2903  C  CA    . ALA B 1 154 ? 207.686 224.657 188.561 1.00 14.67  ? 154 ALA B CA    1 
ATOM   2904  C  C     . ALA B 1 154 ? 207.284 224.553 187.094 1.00 16.59  ? 154 ALA B C     1 
ATOM   2905  O  O     . ALA B 1 154 ? 206.489 225.350 186.615 1.00 20.48  ? 154 ALA B O     1 
ATOM   2906  C  CB    . ALA B 1 154 ? 207.933 223.291 189.183 1.00 14.54  ? 154 ALA B CB    1 
ATOM   2907  N  N     . SER B 1 155 ? 207.844 223.591 186.370 1.00 18.12  ? 155 SER B N     1 
ATOM   2908  C  CA    . SER B 1 155 ? 207.436 223.315 185.002 1.00 19.02  ? 155 SER B CA    1 
ATOM   2909  C  C     . SER B 1 155 ? 207.537 221.817 184.757 1.00 17.91  ? 155 SER B C     1 
ATOM   2910  O  O     . SER B 1 155 ? 208.206 221.089 185.492 1.00 17.48  ? 155 SER B O     1 
ATOM   2911  C  CB    . SER B 1 155 ? 208.295 224.088 183.999 1.00 20.68  ? 155 SER B CB    1 
ATOM   2912  O  OG    . SER B 1 155 ? 207.966 223.737 182.659 1.00 22.54  ? 155 SER B OG    1 
ATOM   2913  N  N     . VAL B 1 156 ? 206.878 221.357 183.691 1.00 18.09  ? 156 VAL B N     1 
ATOM   2914  C  CA    . VAL B 1 156 ? 207.117 220.014 183.193 1.00 19.23  ? 156 VAL B CA    1 
ATOM   2915  C  C     . VAL B 1 156 ? 208.581 219.853 182.786 1.00 18.08  ? 156 VAL B C     1 
ATOM   2916  O  O     . VAL B 1 156 ? 209.092 218.737 182.766 1.00 18.02  ? 156 VAL B O     1 
ATOM   2917  C  CB    . VAL B 1 156 ? 206.144 219.724 182.037 1.00 21.88  ? 156 VAL B CB    1 
ATOM   2918  C  CG1   . VAL B 1 156 ? 206.542 218.516 181.221 1.00 25.10  ? 156 VAL B CG1   1 
ATOM   2919  C  CG2   . VAL B 1 156 ? 204.718 219.601 182.583 1.00 23.24  ? 156 VAL B CG2   1 
ATOM   2920  N  N     . ALA B 1 157 ? 209.258 220.965 182.472 1.00 17.84  ? 157 ALA B N     1 
ATOM   2921  C  CA    . ALA B 1 157 ? 210.678 220.927 182.148 1.00 18.48  ? 157 ALA B CA    1 
ATOM   2922  C  C     . ALA B 1 157 ? 211.519 220.407 183.319 1.00 18.65  ? 157 ALA B C     1 
ATOM   2923  O  O     . ALA B 1 157 ? 212.633 219.944 183.106 1.00 16.78  ? 157 ALA B O     1 
ATOM   2924  C  CB    . ALA B 1 157 ? 211.157 222.303 181.741 1.00 18.24  ? 157 ALA B CB    1 
ATOM   2925  N  N     . ALA B 1 158 ? 210.978 220.452 184.543 1.00 19.43  ? 158 ALA B N     1 
ATOM   2926  C  CA    . ALA B 1 158 ? 211.669 219.863 185.685 1.00 20.29  ? 158 ALA B CA    1 
ATOM   2927  C  C     . ALA B 1 158 ? 211.775 218.350 185.559 1.00 19.54  ? 158 ALA B C     1 
ATOM   2928  O  O     . ALA B 1 158 ? 212.608 217.746 186.226 1.00 21.08  ? 158 ALA B O     1 
ATOM   2929  C  CB    . ALA B 1 158 ? 210.972 220.258 186.971 1.00 21.38  ? 158 ALA B CB    1 
ATOM   2930  N  N     . PHE B 1 159 ? 210.930 217.733 184.716 1.00 20.52  ? 159 PHE B N     1 
ATOM   2931  C  CA    . PHE B 1 159 ? 210.908 216.285 184.573 1.00 22.92  ? 159 PHE B CA    1 
ATOM   2932  C  C     . PHE B 1 159 ? 211.449 215.840 183.216 1.00 24.12  ? 159 PHE B C     1 
ATOM   2933  O  O     . PHE B 1 159 ? 212.282 214.930 183.164 1.00 25.11  ? 159 PHE B O     1 
ATOM   2934  C  CB    . PHE B 1 159 ? 209.492 215.756 184.790 1.00 23.98  ? 159 PHE B CB    1 
ATOM   2935  C  CG    . PHE B 1 159 ? 208.919 216.185 186.129 1.00 26.50  ? 159 PHE B CG    1 
ATOM   2936  C  CD1   . PHE B 1 159 ? 209.423 215.665 187.318 1.00 28.87  ? 159 PHE B CD1   1 
ATOM   2937  C  CD2   . PHE B 1 159 ? 207.887 217.114 186.187 1.00 28.03  ? 159 PHE B CD2   1 
ATOM   2938  C  CE1   . PHE B 1 159 ? 208.914 216.084 188.539 1.00 30.11  ? 159 PHE B CE1   1 
ATOM   2939  C  CE2   . PHE B 1 159 ? 207.364 217.511 187.406 1.00 28.61  ? 159 PHE B CE2   1 
ATOM   2940  C  CZ    . PHE B 1 159 ? 207.873 216.989 188.579 1.00 29.62  ? 159 PHE B CZ    1 
ATOM   2941  N  N     . GLU B 1 160 ? 210.968 216.463 182.130 1.00 25.40  ? 160 GLU B N     1 
ATOM   2942  C  CA    . GLU B 1 160 ? 211.542 216.207 180.816 1.00 29.10  ? 160 GLU B CA    1 
ATOM   2943  C  C     . GLU B 1 160 ? 211.806 217.547 180.132 1.00 25.66  ? 160 GLU B C     1 
ATOM   2944  O  O     . GLU B 1 160 ? 211.022 218.009 179.314 1.00 26.44  ? 160 GLU B O     1 
ATOM   2945  C  CB    . GLU B 1 160 ? 210.720 215.243 179.958 1.00 33.96  ? 160 GLU B CB    1 
ATOM   2946  C  CG    . GLU B 1 160 ? 209.307 215.690 179.616 1.00 39.43  ? 160 GLU B CG    1 
ATOM   2947  C  CD    . GLU B 1 160 ? 208.273 215.359 180.677 1.00 44.44  ? 160 GLU B CD    1 
ATOM   2948  O  OE1   . GLU B 1 160 ? 208.649 215.013 181.811 1.00 48.47  ? 160 GLU B OE1   1 
ATOM   2949  O  OE2   . GLU B 1 160 ? 207.062 215.469 180.396 1.00 45.55  ? 160 GLU B OE2   1 
ATOM   2950  N  N     . GLY B 1 161 ? 212.947 218.146 180.454 1.00 21.42  ? 161 GLY B N     1 
ATOM   2951  C  CA    . GLY B 1 161 ? 213.350 219.381 179.817 1.00 20.57  ? 161 GLY B CA    1 
ATOM   2952  C  C     . GLY B 1 161 ? 213.838 219.117 178.393 1.00 19.83  ? 161 GLY B C     1 
ATOM   2953  O  O     . GLY B 1 161 ? 214.447 218.095 178.104 1.00 17.62  ? 161 GLY B O     1 
ATOM   2954  N  N     . GLN B 1 162 ? 213.510 220.052 177.505 1.00 21.66  ? 162 GLN B N     1 
ATOM   2955  C  CA    . GLN B 1 162 ? 213.817 219.906 176.092 1.00 22.85  ? 162 GLN B CA    1 
ATOM   2956  C  C     . GLN B 1 162 ? 215.251 220.363 175.829 1.00 20.22  ? 162 GLN B C     1 
ATOM   2957  O  O     . GLN B 1 162 ? 215.931 220.899 176.707 1.00 18.68  ? 162 GLN B O     1 
ATOM   2958  C  CB    . GLN B 1 162 ? 212.849 220.765 175.280 1.00 25.50  ? 162 GLN B CB    1 
ATOM   2959  C  CG    . GLN B 1 162 ? 211.380 220.435 175.480 1.00 28.96  ? 162 GLN B CG    1 
ATOM   2960  C  CD    . GLN B 1 162 ? 210.531 221.028 174.380 1.00 32.87  ? 162 GLN B CD    1 
ATOM   2961  O  OE1   . GLN B 1 162 ? 210.157 222.208 174.424 1.00 36.49  ? 162 GLN B OE1   1 
ATOM   2962  N  NE2   . GLN B 1 162 ? 210.239 220.219 173.367 1.00 34.85  ? 162 GLN B NE2   1 
ATOM   2963  N  N     . VAL B 1 163 ? 215.707 220.153 174.590 1.00 19.27  ? 163 VAL B N     1 
ATOM   2964  C  CA    . VAL B 1 163 ? 216.966 220.726 174.150 1.00 18.42  ? 163 VAL B CA    1 
ATOM   2965  C  C     . VAL B 1 163 ? 216.921 222.242 174.298 1.00 16.84  ? 163 VAL B C     1 
ATOM   2966  O  O     . VAL B 1 163 ? 215.979 222.896 173.876 1.00 17.22  ? 163 VAL B O     1 
ATOM   2967  C  CB    . VAL B 1 163 ? 217.277 220.305 172.704 1.00 19.27  ? 163 VAL B CB    1 
ATOM   2968  C  CG1   . VAL B 1 163 ? 218.406 221.132 172.102 1.00 19.41  ? 163 VAL B CG1   1 
ATOM   2969  C  CG2   . VAL B 1 163 ? 217.583 218.821 172.625 1.00 19.59  ? 163 VAL B CG2   1 
ATOM   2970  N  N     . GLY B 1 164 ? 217.972 222.801 174.894 1.00 16.41  ? 164 GLY B N     1 
ATOM   2971  C  CA    . GLY B 1 164 ? 218.071 224.235 175.109 1.00 16.24  ? 164 GLY B CA    1 
ATOM   2972  C  C     . GLY B 1 164 ? 217.417 224.698 176.417 1.00 15.74  ? 164 GLY B C     1 
ATOM   2973  O  O     . GLY B 1 164 ? 217.415 225.891 176.701 1.00 15.51  ? 164 GLY B O     1 
ATOM   2974  N  N     . GLN B 1 165 ? 216.899 223.767 177.230 1.00 16.60  ? 165 GLN B N     1 
ATOM   2975  C  CA    . GLN B 1 165 ? 216.178 224.143 178.440 1.00 17.40  ? 165 GLN B CA    1 
ATOM   2976  C  C     . GLN B 1 165 ? 216.953 223.787 179.711 1.00 15.42  ? 165 GLN B C     1 
ATOM   2977  O  O     . GLN B 1 165 ? 216.348 223.654 180.771 1.00 18.29  ? 165 GLN B O     1 
ATOM   2978  C  CB    . GLN B 1 165 ? 214.837 223.406 178.472 1.00 18.84  ? 165 GLN B CB    1 
ATOM   2979  C  CG    . GLN B 1 165 ? 213.687 224.116 177.779 1.00 21.07  ? 165 GLN B CG    1 
ATOM   2980  C  CD    . GLN B 1 165 ? 212.351 223.559 178.218 1.00 21.84  ? 165 GLN B CD    1 
ATOM   2981  O  OE1   . GLN B 1 165 ? 212.163 222.338 178.254 1.00 21.52  ? 165 GLN B OE1   1 
ATOM   2982  N  NE2   . GLN B 1 165 ? 211.423 224.438 178.573 1.00 23.33  ? 165 GLN B NE2   1 
ATOM   2983  N  N     . ALA B 1 166 ? 218.279 223.634 179.620 1.00 14.48  ? 166 ALA B N     1 
ATOM   2984  C  CA    . ALA B 1 166 ? 219.080 223.239 180.767 1.00 14.46  ? 166 ALA B CA    1 
ATOM   2985  C  C     . ALA B 1 166 ? 218.890 224.207 181.942 1.00 13.82  ? 166 ALA B C     1 
ATOM   2986  O  O     . ALA B 1 166 ? 218.680 223.770 183.071 1.00 13.45  ? 166 ALA B O     1 
ATOM   2987  C  CB    . ALA B 1 166 ? 220.542 223.131 180.390 1.00 13.99  ? 166 ALA B CB    1 
ATOM   2988  N  N     . ALA B 1 167 ? 218.985 225.513 181.689 1.00 12.88  ? 167 ALA B N     1 
ATOM   2989  C  CA    . ALA B 1 167 ? 218.867 226.495 182.748 1.00 12.97  ? 167 ALA B CA    1 
ATOM   2990  C  C     . ALA B 1 167 ? 217.469 226.467 183.352 1.00 13.68  ? 167 ALA B C     1 
ATOM   2991  O  O     . ALA B 1 167 ? 217.305 226.486 184.564 1.00 13.24  ? 167 ALA B O     1 
ATOM   2992  C  CB    . ALA B 1 167 ? 219.203 227.875 182.233 1.00 13.51  ? 167 ALA B CB    1 
ATOM   2993  N  N     . TYR B 1 168 ? 216.453 226.424 182.491 1.00 12.99  ? 168 TYR B N     1 
ATOM   2994  C  CA    . TYR B 1 168 ? 215.083 226.425 182.943 1.00 13.49  ? 168 TYR B CA    1 
ATOM   2995  C  C     . TYR B 1 168 ? 214.785 225.150 183.728 1.00 11.65  ? 168 TYR B C     1 
ATOM   2996  O  O     . TYR B 1 168 ? 214.138 225.203 184.763 1.00 12.25  ? 168 TYR B O     1 
ATOM   2997  C  CB    . TYR B 1 168 ? 214.169 226.588 181.726 1.00 15.40  ? 168 TYR B CB    1 
ATOM   2998  C  CG    . TYR B 1 168 ? 212.730 226.894 182.085 1.00 17.32  ? 168 TYR B CG    1 
ATOM   2999  C  CD1   . TYR B 1 168 ? 212.402 228.129 182.616 1.00 19.75  ? 168 TYR B CD1   1 
ATOM   3000  C  CD2   . TYR B 1 168 ? 211.712 225.970 181.875 1.00 20.20  ? 168 TYR B CD2   1 
ATOM   3001  C  CE1   . TYR B 1 168 ? 211.089 228.443 182.940 1.00 21.85  ? 168 TYR B CE1   1 
ATOM   3002  C  CE2   . TYR B 1 168 ? 210.396 226.269 182.205 1.00 20.81  ? 168 TYR B CE2   1 
ATOM   3003  C  CZ    . TYR B 1 168 ? 210.089 227.505 182.740 1.00 21.69  ? 168 TYR B CZ    1 
ATOM   3004  O  OH    . TYR B 1 168 ? 208.798 227.806 183.074 1.00 24.80  ? 168 TYR B OH    1 
ATOM   3005  N  N     . SER B 1 169 ? 215.231 224.003 183.225 1.00 10.72  ? 169 SER B N     1 
ATOM   3006  C  CA    . SER B 1 169 ? 214.994 222.728 183.884 1.00 10.32  ? 169 SER B CA    1 
ATOM   3007  C  C     . SER B 1 169 ? 215.688 222.656 185.246 1.00 9.65   ? 169 SER B C     1 
ATOM   3008  O  O     . SER B 1 169 ? 215.135 222.100 186.190 1.00 9.16   ? 169 SER B O     1 
ATOM   3009  C  CB    . SER B 1 169 ? 215.418 221.575 183.010 1.00 10.59  ? 169 SER B CB    1 
ATOM   3010  O  OG    . SER B 1 169 ? 214.615 221.522 181.848 1.00 11.17  ? 169 SER B OG    1 
ATOM   3011  N  N     . ALA B 1 170 ? 216.903 223.209 185.340 1.00 8.94   ? 170 ALA B N     1 
ATOM   3012  C  CA    . ALA B 1 170 ? 217.617 223.252 186.606 1.00 8.74   ? 170 ALA B CA    1 
ATOM   3013  C  C     . ALA B 1 170 ? 216.825 224.059 187.636 1.00 8.79   ? 170 ALA B C     1 
ATOM   3014  O  O     . ALA B 1 170 ? 216.655 223.614 188.773 1.00 8.56   ? 170 ALA B O     1 
ATOM   3015  C  CB    . ALA B 1 170 ? 219.000 223.828 186.431 1.00 8.75   ? 170 ALA B CB    1 
ATOM   3016  N  N     . SER B 1 171 ? 216.355 225.245 187.243 1.00 8.70   ? 171 SER B N     1 
ATOM   3017  C  CA    . SER B 1 171 ? 215.626 226.108 188.157 1.00 9.41   ? 171 SER B CA    1 
ATOM   3018  C  C     . SER B 1 171 ? 214.334 225.430 188.600 1.00 10.28  ? 171 SER B C     1 
ATOM   3019  O  O     . SER B 1 171 ? 213.981 225.469 189.772 1.00 11.37  ? 171 SER B O     1 
ATOM   3020  C  CB    . SER B 1 171 ? 215.365 227.468 187.547 1.00 9.84   ? 171 SER B CB    1 
ATOM   3021  O  OG    . SER B 1 171 ? 214.355 227.396 186.555 1.00 9.65   ? 171 SER B OG    1 
ATOM   3022  N  N     . LYS B 1 172 ? 213.607 224.822 187.657 1.00 9.94   ? 172 LYS B N     1 
ATOM   3023  C  CA    . LYS B 1 172 ? 212.349 224.188 187.987 1.00 10.42  ? 172 LYS B CA    1 
ATOM   3024  C  C     . LYS B 1 172 ? 212.560 222.887 188.745 1.00 9.03   ? 172 LYS B C     1 
ATOM   3025  O  O     . LYS B 1 172 ? 211.777 222.562 189.626 1.00 8.76   ? 172 LYS B O     1 
ATOM   3026  C  CB    . LYS B 1 172 ? 211.512 223.979 186.720 1.00 11.85  ? 172 LYS B CB    1 
ATOM   3027  C  CG    . LYS B 1 172 ? 211.118 225.292 186.026 1.00 13.11  ? 172 LYS B CG    1 
ATOM   3028  C  CD    . LYS B 1 172 ? 210.736 226.416 186.974 1.00 13.53  ? 172 LYS B CD    1 
ATOM   3029  C  CE    . LYS B 1 172 ? 210.036 227.548 186.274 1.00 14.55  ? 172 LYS B CE    1 
ATOM   3030  N  NZ    . LYS B 1 172 ? 209.250 228.386 187.187 1.00 14.24  ? 172 LYS B NZ    1 
ATOM   3031  N  N     . GLY B 1 173 ? 213.617 222.140 188.414 1.00 8.19   ? 173 GLY B N     1 
ATOM   3032  C  CA    . GLY B 1 173 ? 213.986 220.968 189.191 1.00 7.58   ? 173 GLY B CA    1 
ATOM   3033  C  C     . GLY B 1 173 ? 214.348 221.343 190.631 1.00 7.44   ? 173 GLY B C     1 
ATOM   3034  O  O     . GLY B 1 173 ? 214.107 220.580 191.562 1.00 7.07   ? 173 GLY B O     1 
ATOM   3035  N  N     . GLY B 1 174 ? 214.953 222.523 190.819 1.00 7.21   ? 174 GLY B N     1 
ATOM   3036  C  CA    . GLY B 1 174 ? 215.246 223.019 192.149 1.00 7.39   ? 174 GLY B CA    1 
ATOM   3037  C  C     . GLY B 1 174 ? 213.970 223.297 192.949 1.00 7.12   ? 174 GLY B C     1 
ATOM   3038  O  O     . GLY B 1 174 ? 213.899 223.003 194.133 1.00 6.90   ? 174 GLY B O     1 
ATOM   3039  N  N     . ILE B 1 175 ? 212.966 223.878 192.300 1.00 7.29   ? 175 ILE B N     1 
ATOM   3040  C  CA    . ILE B 1 175 ? 211.697 224.147 192.963 1.00 8.12   ? 175 ILE B CA    1 
ATOM   3041  C  C     . ILE B 1 175 ? 211.037 222.839 193.390 1.00 8.32   ? 175 ILE B C     1 
ATOM   3042  O  O     . ILE B 1 175 ? 210.541 222.726 194.508 1.00 8.76   ? 175 ILE B O     1 
ATOM   3043  C  CB    . ILE B 1 175 ? 210.770 224.982 192.057 1.00 8.50   ? 175 ILE B CB    1 
ATOM   3044  C  CG1   . ILE B 1 175 ? 211.331 226.391 191.895 1.00 8.95   ? 175 ILE B CG1   1 
ATOM   3045  C  CG2   . ILE B 1 175 ? 209.349 225.024 192.627 1.00 8.46   ? 175 ILE B CG2   1 
ATOM   3046  C  CD1   . ILE B 1 175 ? 210.810 227.125 190.693 1.00 9.76   ? 175 ILE B CD1   1 
ATOM   3047  N  N     . VAL B 1 176 ? 211.038 221.845 192.504 1.00 8.45   ? 176 VAL B N     1 
ATOM   3048  C  CA    . VAL B 1 176 ? 210.478 220.547 192.839 1.00 9.02   ? 176 VAL B CA    1 
ATOM   3049  C  C     . VAL B 1 176 ? 211.263 219.929 193.996 1.00 8.91   ? 176 VAL B C     1 
ATOM   3050  O  O     . VAL B 1 176 ? 210.679 219.371 194.916 1.00 9.27   ? 176 VAL B O     1 
ATOM   3051  C  CB    . VAL B 1 176 ? 210.474 219.637 191.595 1.00 9.75   ? 176 VAL B CB    1 
ATOM   3052  C  CG1   . VAL B 1 176 ? 210.245 218.173 191.956 1.00 10.15  ? 176 VAL B CG1   1 
ATOM   3053  C  CG2   . VAL B 1 176 ? 209.479 220.145 190.556 1.00 9.79   ? 176 VAL B CG2   1 
ATOM   3054  N  N     . GLY B 1 177 ? 212.593 220.028 193.955 1.00 8.54   ? 177 GLY B N     1 
ATOM   3055  C  CA    . GLY B 1 177 ? 213.426 219.412 194.972 1.00 8.31   ? 177 GLY B CA    1 
ATOM   3056  C  C     . GLY B 1 177 ? 213.170 219.980 196.364 1.00 8.49   ? 177 GLY B C     1 
ATOM   3057  O  O     . GLY B 1 177 ? 213.164 219.247 197.342 1.00 8.84   ? 177 GLY B O     1 
ATOM   3058  N  N     . MET B 1 178 ? 212.972 221.294 196.466 1.00 8.35   ? 178 MET B N     1 
ATOM   3059  C  CA    . MET B 1 178 ? 212.854 221.929 197.764 1.00 8.67   ? 178 MET B CA    1 
ATOM   3060  C  C     . MET B 1 178 ? 211.408 221.997 198.262 1.00 8.29   ? 178 MET B C     1 
ATOM   3061  O  O     . MET B 1 178 ? 211.186 222.459 199.372 1.00 8.09   ? 178 MET B O     1 
ATOM   3062  C  CB    . MET B 1 178 ? 213.450 223.336 197.735 1.00 9.00   ? 178 MET B CB    1 
ATOM   3063  C  CG    . MET B 1 178 ? 212.705 224.303 196.840 1.00 9.47   ? 178 MET B CG    1 
ATOM   3064  S  SD    . MET B 1 178 ? 213.528 225.914 196.880 1.00 11.18  ? 178 MET B SD    1 
ATOM   3065  C  CE    . MET B 1 178 ? 212.231 226.930 196.165 1.00 11.09  ? 178 MET B CE    1 
ATOM   3066  N  N     . THR B 1 179 ? 210.438 221.522 197.483 1.00 8.22   ? 179 THR B N     1 
ATOM   3067  C  CA    . THR B 1 179 ? 209.038 221.589 197.890 1.00 8.12   ? 179 THR B CA    1 
ATOM   3068  C  C     . THR B 1 179 ? 208.821 220.777 199.170 1.00 7.93   ? 179 THR B C     1 
ATOM   3069  O  O     . THR B 1 179 ? 208.256 221.284 200.128 1.00 7.67   ? 179 THR B O     1 
ATOM   3070  C  CB    . THR B 1 179 ? 208.123 221.091 196.772 1.00 8.37   ? 179 THR B CB    1 
ATOM   3071  O  OG1   . THR B 1 179 ? 208.220 221.984 195.664 1.00 8.40   ? 179 THR B OG1   1 
ATOM   3072  C  CG2   . THR B 1 179 ? 206.675 220.997 197.231 1.00 8.65   ? 179 THR B CG2   1 
ATOM   3073  N  N     . LEU B 1 180 ? 209.271 219.524 199.188 1.00 8.07   ? 180 LEU B N     1 
ATOM   3074  C  CA    . LEU B 1 180 ? 209.074 218.678 200.350 1.00 7.98   ? 180 LEU B CA    1 
ATOM   3075  C  C     . LEU B 1 180 ? 209.841 219.182 201.573 1.00 7.61   ? 180 LEU B C     1 
ATOM   3076  O  O     . LEU B 1 180 ? 209.265 219.263 202.656 1.00 7.56   ? 180 LEU B O     1 
ATOM   3077  C  CB    . LEU B 1 180 ? 209.414 217.220 200.034 1.00 8.24   ? 180 LEU B CB    1 
ATOM   3078  C  CG    . LEU B 1 180 ? 209.217 216.257 201.205 1.00 8.67   ? 180 LEU B CG    1 
ATOM   3079  C  CD1   . LEU B 1 180 ? 207.774 216.238 201.671 1.00 8.84   ? 180 LEU B CD1   1 
ATOM   3080  C  CD2   . LEU B 1 180 ? 209.672 214.860 200.833 1.00 9.04   ? 180 LEU B CD2   1 
ATOM   3081  N  N     . PRO B 1 181 ? 211.154 219.488 201.500 1.00 7.88   ? 181 PRO B N     1 
ATOM   3082  C  CA    . PRO B 1 181 ? 211.845 219.986 202.691 1.00 7.86   ? 181 PRO B CA    1 
ATOM   3083  C  C     . PRO B 1 181 ? 211.240 221.260 203.278 1.00 6.99   ? 181 PRO B C     1 
ATOM   3084  O  O     . PRO B 1 181 ? 211.173 221.411 204.495 1.00 7.16   ? 181 PRO B O     1 
ATOM   3085  C  CB    . PRO B 1 181 ? 213.305 220.197 202.283 1.00 8.09   ? 181 PRO B CB    1 
ATOM   3086  C  CG    . PRO B 1 181 ? 213.403 219.740 200.858 1.00 8.39   ? 181 PRO B CG    1 
ATOM   3087  C  CD    . PRO B 1 181 ? 212.044 219.316 200.339 1.00 8.16   ? 181 PRO B CD    1 
ATOM   3088  N  N     . ILE B 1 182 ? 210.789 222.172 202.426 1.00 6.88   ? 182 ILE B N     1 
ATOM   3089  C  CA    . ILE B 1 182 ? 210.172 223.393 202.930 1.00 6.82   ? 182 ILE B CA    1 
ATOM   3090  C  C     . ILE B 1 182 ? 208.825 223.071 203.570 1.00 6.74   ? 182 ILE B C     1 
ATOM   3091  O  O     . ILE B 1 182 ? 208.489 223.636 204.611 1.00 6.99   ? 182 ILE B O     1 
ATOM   3092  C  CB    . ILE B 1 182 ? 210.055 224.444 201.815 1.00 7.09   ? 182 ILE B CB    1 
ATOM   3093  C  CG1   . ILE B 1 182 ? 211.429 224.887 201.343 1.00 7.20   ? 182 ILE B CG1   1 
ATOM   3094  C  CG2   . ILE B 1 182 ? 209.226 225.637 202.281 1.00 7.25   ? 182 ILE B CG2   1 
ATOM   3095  C  CD1   . ILE B 1 182 ? 211.375 225.839 200.175 1.00 7.40   ? 182 ILE B CD1   1 
ATOM   3096  N  N     . ALA B 1 183 ? 208.049 222.172 202.950 1.00 6.42   ? 183 ALA B N     1 
ATOM   3097  C  CA    . ALA B 1 183 ? 206.807 221.713 203.555 1.00 6.38   ? 183 ALA B CA    1 
ATOM   3098  C  C     . ALA B 1 183 ? 207.084 221.091 204.923 1.00 6.60   ? 183 ALA B C     1 
ATOM   3099  O  O     . ALA B 1 183 ? 206.343 221.322 205.869 1.00 6.52   ? 183 ALA B O     1 
ATOM   3100  C  CB    . ALA B 1 183 ? 206.083 220.751 202.642 1.00 6.35   ? 183 ALA B CB    1 
ATOM   3101  N  N     . ARG B 1 184 ? 208.152 220.294 205.017 1.00 6.94   ? 184 ARG B N     1 
ATOM   3102  C  CA    . ARG B 1 184 ? 208.556 219.730 206.290 1.00 7.64   ? 184 ARG B CA    1 
ATOM   3103  C  C     . ARG B 1 184 ? 209.019 220.826 207.249 1.00 8.18   ? 184 ARG B C     1 
ATOM   3104  O  O     . ARG B 1 184 ? 208.740 220.754 208.438 1.00 8.19   ? 184 ARG B O     1 
ATOM   3105  C  CB    . ARG B 1 184 ? 209.655 218.685 206.074 1.00 7.83   ? 184 ARG B CB    1 
ATOM   3106  C  CG    . ARG B 1 184 ? 209.141 217.435 205.370 1.00 7.92   ? 184 ARG B CG    1 
ATOM   3107  C  CD    . ARG B 1 184 ? 210.309 216.541 204.964 1.00 8.17   ? 184 ARG B CD    1 
ATOM   3108  N  NE    . ARG B 1 184 ? 209.850 215.175 204.716 1.00 8.43   ? 184 ARG B NE    1 
ATOM   3109  C  CZ    . ARG B 1 184 ? 210.606 214.137 204.423 1.00 8.74   ? 184 ARG B CZ    1 
ATOM   3110  N  NH1   . ARG B 1 184 ? 211.914 214.271 204.254 1.00 8.86   ? 184 ARG B NH1   1 
ATOM   3111  N  NH2   . ARG B 1 184 ? 210.023 212.965 204.272 1.00 9.15   ? 184 ARG B NH2   1 
ATOM   3112  N  N     . ASP B 1 185 ? 209.754 221.822 206.737 1.00 9.06   ? 185 ASP B N     1 
ATOM   3113  C  CA    . ASP B 1 185 ? 210.197 222.933 207.562 1.00 9.93   ? 185 ASP B CA    1 
ATOM   3114  C  C     . ASP B 1 185 ? 209.008 223.667 208.192 1.00 9.97   ? 185 ASP B C     1 
ATOM   3115  O  O     . ASP B 1 185 ? 209.024 223.960 209.387 1.00 9.47   ? 185 ASP B O     1 
ATOM   3116  C  CB    . ASP B 1 185 ? 210.980 223.939 206.745 1.00 11.32  ? 185 ASP B CB    1 
ATOM   3117  C  CG    . ASP B 1 185 ? 212.449 223.634 206.564 1.00 13.27  ? 185 ASP B CG    1 
ATOM   3118  O  OD1   . ASP B 1 185 ? 212.918 222.670 207.200 1.00 15.62  ? 185 ASP B OD1   1 
ATOM   3119  O  OD2   . ASP B 1 185 ? 213.103 224.392 205.799 1.00 14.52  ? 185 ASP B OD2   1 
ATOM   3120  N  N     . LEU B 1 186 ? 207.976 223.957 207.387 1.00 9.36   ? 186 LEU B N     1 
ATOM   3121  C  CA    . LEU B 1 186 ? 206.878 224.809 207.804 1.00 10.05  ? 186 LEU B CA    1 
ATOM   3122  C  C     . LEU B 1 186 ? 205.690 224.024 208.354 1.00 10.33  ? 186 LEU B C     1 
ATOM   3123  O  O     . LEU B 1 186 ? 204.692 224.638 208.722 1.00 10.85  ? 186 LEU B O     1 
ATOM   3124  C  CB    . LEU B 1 186 ? 206.441 225.660 206.616 1.00 9.47   ? 186 LEU B CB    1 
ATOM   3125  C  CG    . LEU B 1 186 ? 207.543 226.519 205.996 1.00 9.86   ? 186 LEU B CG    1 
ATOM   3126  C  CD1   . LEU B 1 186 ? 206.962 227.381 204.885 1.00 9.75   ? 186 LEU B CD1   1 
ATOM   3127  C  CD2   . LEU B 1 186 ? 208.223 227.380 207.055 1.00 9.92   ? 186 LEU B CD2   1 
ATOM   3128  N  N     . ALA B 1 187 ? 205.796 222.692 208.420 1.00 11.18  ? 187 ALA B N     1 
ATOM   3129  C  CA    . ALA B 1 187 ? 204.698 221.875 208.919 1.00 12.48  ? 187 ALA B CA    1 
ATOM   3130  C  C     . ALA B 1 187 ? 204.349 222.225 210.369 1.00 13.97  ? 187 ALA B C     1 
ATOM   3131  O  O     . ALA B 1 187 ? 203.167 222.345 210.689 1.00 15.69  ? 187 ALA B O     1 
ATOM   3132  C  CB    . ALA B 1 187 ? 205.025 220.403 208.768 1.00 12.22  ? 187 ALA B CB    1 
ATOM   3133  N  N     . PRO B 1 188 ? 205.303 222.384 211.315 1.00 16.01  ? 188 PRO B N     1 
ATOM   3134  C  CA    . PRO B 1 188 ? 204.932 222.813 212.670 1.00 17.51  ? 188 PRO B CA    1 
ATOM   3135  C  C     . PRO B 1 188 ? 204.236 224.171 212.716 1.00 18.34  ? 188 PRO B C     1 
ATOM   3136  O  O     . PRO B 1 188 ? 203.459 224.430 213.624 1.00 21.39  ? 188 PRO B O     1 
ATOM   3137  C  CB    . PRO B 1 188 ? 206.269 222.842 213.426 1.00 18.20  ? 188 PRO B CB    1 
ATOM   3138  C  CG    . PRO B 1 188 ? 207.161 221.920 212.630 1.00 18.11  ? 188 PRO B CG    1 
ATOM   3139  C  CD    . PRO B 1 188 ? 206.747 222.124 211.192 1.00 16.74  ? 188 PRO B CD    1 
ATOM   3140  N  N     . ILE B 1 189 ? 204.501 225.032 211.745 1.00 18.30  ? 189 ILE B N     1 
ATOM   3141  C  CA    . ILE B 1 189 ? 203.912 226.362 211.718 1.00 20.10  ? 189 ILE B CA    1 
ATOM   3142  C  C     . ILE B 1 189 ? 202.497 226.294 211.134 1.00 17.53  ? 189 ILE B C     1 
ATOM   3143  O  O     . ILE B 1 189 ? 201.682 227.175 211.385 1.00 17.90  ? 189 ILE B O     1 
ATOM   3144  C  CB    . ILE B 1 189 ? 204.805 227.326 210.911 1.00 23.01  ? 189 ILE B CB    1 
ATOM   3145  C  CG1   . ILE B 1 189 ? 206.236 227.314 211.375 1.00 27.80  ? 189 ILE B CG1   1 
ATOM   3146  C  CG2   . ILE B 1 189 ? 204.257 228.744 210.944 1.00 26.08  ? 189 ILE B CG2   1 
ATOM   3147  C  CD1   . ILE B 1 189 ? 207.120 228.274 210.606 1.00 29.29  ? 189 ILE B CD1   1 
ATOM   3148  N  N     . GLY B 1 190 ? 202.203 225.238 210.363 1.00 14.17  ? 190 GLY B N     1 
ATOM   3149  C  CA    . GLY B 1 190 ? 200.916 225.095 209.716 1.00 12.13  ? 190 GLY B CA    1 
ATOM   3150  C  C     . GLY B 1 190 ? 200.847 225.832 208.382 1.00 10.15  ? 190 GLY B C     1 
ATOM   3151  O  O     . GLY B 1 190 ? 199.773 226.274 207.998 1.00 10.34  ? 190 GLY B O     1 
ATOM   3152  N  N     . ILE B 1 191 ? 201.961 225.866 207.642 1.00 9.05   ? 191 ILE B N     1 
ATOM   3153  C  CA    . ILE B 1 191 ? 201.979 226.449 206.312 1.00 8.13   ? 191 ILE B CA    1 
ATOM   3154  C  C     . ILE B 1 191 ? 202.161 225.322 205.306 1.00 7.62   ? 191 ILE B C     1 
ATOM   3155  O  O     . ILE B 1 191 ? 203.203 224.673 205.291 1.00 7.49   ? 191 ILE B O     1 
ATOM   3156  C  CB    . ILE B 1 191 ? 203.083 227.510 206.171 1.00 8.27   ? 191 ILE B CB    1 
ATOM   3157  C  CG1   . ILE B 1 191 ? 202.882 228.640 207.164 1.00 8.19   ? 191 ILE B CG1   1 
ATOM   3158  C  CG2   . ILE B 1 191 ? 203.131 228.036 204.738 1.00 8.05   ? 191 ILE B CG2   1 
ATOM   3159  C  CD1   . ILE B 1 191 ? 204.011 229.650 207.183 1.00 8.43   ? 191 ILE B CD1   1 
ATOM   3160  N  N     . ARG B 1 192 ? 201.151 225.122 204.457 1.00 7.44   ? 192 ARG B N     1 
ATOM   3161  C  CA    . ARG B 1 192 ? 201.237 224.121 203.405 1.00 7.29   ? 192 ARG B CA    1 
ATOM   3162  C  C     . ARG B 1 192 ? 202.055 224.669 202.240 1.00 6.96   ? 192 ARG B C     1 
ATOM   3163  O  O     . ARG B 1 192 ? 201.915 225.826 201.862 1.00 7.37   ? 192 ARG B O     1 
ATOM   3164  C  CB    . ARG B 1 192 ? 199.848 223.708 202.919 1.00 7.04   ? 192 ARG B CB    1 
ATOM   3165  C  CG    . ARG B 1 192 ? 199.052 222.970 203.983 1.00 7.08   ? 192 ARG B CG    1 
ATOM   3166  C  CD    . ARG B 1 192 ? 197.805 222.338 203.417 1.00 6.93   ? 192 ARG B CD    1 
ATOM   3167  N  NE    . ARG B 1 192 ? 196.786 223.327 203.068 1.00 6.75   ? 192 ARG B NE    1 
ATOM   3168  C  CZ    . ARG B 1 192 ? 196.318 223.563 201.857 1.00 6.81   ? 192 ARG B CZ    1 
ATOM   3169  N  NH1   . ARG B 1 192 ? 196.783 222.912 200.807 1.00 6.82   ? 192 ARG B NH1   1 
ATOM   3170  N  NH2   . ARG B 1 192 ? 195.365 224.462 201.683 1.00 6.96   ? 192 ARG B NH2   1 
ATOM   3171  N  N     . VAL B 1 193 ? 202.900 223.805 201.672 1.00 6.76   ? 193 VAL B N     1 
ATOM   3172  C  CA    . VAL B 1 193 ? 203.734 224.169 200.546 1.00 6.65   ? 193 VAL B CA    1 
ATOM   3173  C  C     . VAL B 1 193 ? 203.431 223.206 199.409 1.00 6.44   ? 193 VAL B C     1 
ATOM   3174  O  O     . VAL B 1 193 ? 203.583 221.998 199.558 1.00 6.54   ? 193 VAL B O     1 
ATOM   3175  C  CB    . VAL B 1 193 ? 205.231 224.172 200.893 1.00 6.86   ? 193 VAL B CB    1 
ATOM   3176  C  CG1   . VAL B 1 193 ? 206.051 224.704 199.737 1.00 6.99   ? 193 VAL B CG1   1 
ATOM   3177  C  CG2   . VAL B 1 193 ? 205.507 224.970 202.162 1.00 7.17   ? 193 VAL B CG2   1 
ATOM   3178  N  N     . MET B 1 194 ? 202.986 223.751 198.281 1.00 6.54   ? 194 MET B N     1 
ATOM   3179  C  CA    . MET B 1 194 ? 202.614 222.968 197.122 1.00 6.96   ? 194 MET B CA    1 
ATOM   3180  C  C     . MET B 1 194 ? 203.274 223.561 195.886 1.00 6.74   ? 194 MET B C     1 
ATOM   3181  O  O     . MET B 1 194 ? 203.610 224.741 195.854 1.00 7.02   ? 194 MET B O     1 
ATOM   3182  C  CB    . MET B 1 194 ? 201.088 222.978 196.903 1.00 7.57   ? 194 MET B CB    1 
ATOM   3183  C  CG    . MET B 1 194 ? 200.312 222.127 197.851 1.00 8.13   ? 194 MET B CG    1 
ATOM   3184  S  SD    . MET B 1 194 ? 200.707 220.387 197.636 1.00 8.50   ? 194 MET B SD    1 
ATOM   3185  C  CE    . MET B 1 194 ? 200.032 220.040 196.017 1.00 8.96   ? 194 MET B CE    1 
ATOM   3186  N  N     . THR B 1 195 ? 203.446 222.719 194.871 1.00 6.87   ? 195 THR B N     1 
ATOM   3187  C  CA    . THR B 1 195 ? 204.051 223.140 193.624 1.00 7.13   ? 195 THR B CA    1 
ATOM   3188  C  C     . THR B 1 195 ? 203.184 222.653 192.469 1.00 7.29   ? 195 THR B C     1 
ATOM   3189  O  O     . THR B 1 195 ? 202.763 221.499 192.454 1.00 7.27   ? 195 THR B O     1 
ATOM   3190  C  CB    . THR B 1 195 ? 205.479 222.603 193.519 1.00 7.54   ? 195 THR B CB    1 
ATOM   3191  O  OG1   . THR B 1 195 ? 206.274 223.191 194.547 1.00 7.93   ? 195 THR B OG1   1 
ATOM   3192  C  CG2   . THR B 1 195 ? 206.092 222.939 192.177 1.00 7.69   ? 195 THR B CG2   1 
ATOM   3193  N  N     . ILE B 1 196 ? 202.961 223.531 191.499 1.00 7.08   ? 196 ILE B N     1 
ATOM   3194  C  CA    . ILE B 1 196 ? 202.309 223.179 190.253 1.00 7.45   ? 196 ILE B CA    1 
ATOM   3195  C  C     . ILE B 1 196 ? 203.364 223.163 189.151 1.00 7.99   ? 196 ILE B C     1 
ATOM   3196  O  O     . ILE B 1 196 ? 204.183 224.083 189.057 1.00 8.63   ? 196 ILE B O     1 
ATOM   3197  C  CB    . ILE B 1 196 ? 201.173 224.163 189.918 1.00 7.49   ? 196 ILE B CB    1 
ATOM   3198  C  CG1   . ILE B 1 196 ? 200.130 224.177 191.008 1.00 7.48   ? 196 ILE B CG1   1 
ATOM   3199  C  CG2   . ILE B 1 196 ? 200.555 223.850 188.558 1.00 7.64   ? 196 ILE B CG2   1 
ATOM   3200  C  CD1   . ILE B 1 196 ? 199.087 225.271 190.834 1.00 7.78   ? 196 ILE B CD1   1 
ATOM   3201  N  N     . ALA B 1 197 ? 203.327 222.116 188.333 1.00 8.06   ? 197 ALA B N     1 
ATOM   3202  C  CA    . ALA B 1 197 ? 204.220 221.997 187.203 1.00 8.77   ? 197 ALA B CA    1 
ATOM   3203  C  C     . ALA B 1 197 ? 203.424 222.123 185.913 1.00 9.35   ? 197 ALA B C     1 
ATOM   3204  O  O     . ALA B 1 197 ? 202.998 221.125 185.331 1.00 10.02  ? 197 ALA B O     1 
ATOM   3205  C  CB    . ALA B 1 197 ? 204.980 220.684 187.263 1.00 8.71   ? 197 ALA B CB    1 
ATOM   3206  N  N     . PRO B 1 198 ? 203.164 223.346 185.425 1.00 10.41  ? 198 PRO B N     1 
ATOM   3207  C  CA    . PRO B 1 198 ? 202.346 223.497 184.222 1.00 11.17  ? 198 PRO B CA    1 
ATOM   3208  C  C     . PRO B 1 198 ? 203.091 223.016 182.992 1.00 12.02  ? 198 PRO B C     1 
ATOM   3209  O  O     . PRO B 1 198 ? 204.313 223.091 182.931 1.00 11.89  ? 198 PRO B O     1 
ATOM   3210  C  CB    . PRO B 1 198 ? 202.052 224.994 184.148 1.00 11.53  ? 198 PRO B CB    1 
ATOM   3211  C  CG    . PRO B 1 198 ? 203.140 225.626 184.980 1.00 11.39  ? 198 PRO B CG    1 
ATOM   3212  C  CD    . PRO B 1 198 ? 203.546 224.631 186.033 1.00 10.91  ? 198 PRO B CD    1 
ATOM   3213  N  N     . GLY B 1 199 ? 202.331 222.530 182.015 1.00 14.50  ? 199 GLY B N     1 
ATOM   3214  C  CA    . GLY B 1 199 ? 202.895 222.168 180.729 1.00 16.80  ? 199 GLY B CA    1 
ATOM   3215  C  C     . GLY B 1 199 ? 202.933 223.399 179.825 1.00 17.95  ? 199 GLY B C     1 
ATOM   3216  O  O     . GLY B 1 199 ? 203.451 224.444 180.201 1.00 18.41  ? 199 GLY B O     1 
ATOM   3217  N  N     . LEU B 1 200 ? 202.386 223.253 178.622 1.00 21.37  ? 200 LEU B N     1 
ATOM   3218  C  CA    . LEU B 1 200 ? 202.368 224.327 177.639 1.00 22.49  ? 200 LEU B CA    1 
ATOM   3219  C  C     . LEU B 1 200 ? 201.102 225.140 177.859 1.00 21.42  ? 200 LEU B C     1 
ATOM   3220  O  O     . LEU B 1 200 ? 199.996 224.620 177.706 1.00 22.62  ? 200 LEU B O     1 
ATOM   3221  C  CB    . LEU B 1 200 ? 202.387 223.728 176.238 1.00 26.29  ? 200 LEU B CB    1 
ATOM   3222  C  CG    . LEU B 1 200 ? 203.569 222.802 175.934 1.00 29.69  ? 200 LEU B CG    1 
ATOM   3223  C  CD1   . LEU B 1 200 ? 203.360 222.095 174.600 1.00 31.93  ? 200 LEU B CD1   1 
ATOM   3224  C  CD2   . LEU B 1 200 ? 204.837 223.625 175.934 1.00 31.54  ? 200 LEU B CD2   1 
ATOM   3225  N  N     . PHE B 1 201 ? 201.274 226.405 178.240 1.00 21.19  ? 201 PHE B N     1 
ATOM   3226  C  CA    . PHE B 1 201 ? 200.158 227.287 178.526 1.00 23.07  ? 201 PHE B CA    1 
ATOM   3227  C  C     . PHE B 1 201 ? 200.178 228.483 177.584 1.00 26.21  ? 201 PHE B C     1 
ATOM   3228  O  O     . PHE B 1 201 ? 201.238 228.920 177.145 1.00 29.26  ? 201 PHE B O     1 
ATOM   3229  C  CB    . PHE B 1 201 ? 200.188 227.761 179.982 1.00 20.58  ? 201 PHE B CB    1 
ATOM   3230  C  CG    . PHE B 1 201 ? 199.394 226.856 180.895 1.00 18.24  ? 201 PHE B CG    1 
ATOM   3231  C  CD1   . PHE B 1 201 ? 199.866 225.588 181.221 1.00 17.15  ? 201 PHE B CD1   1 
ATOM   3232  C  CD2   . PHE B 1 201 ? 198.189 227.275 181.424 1.00 17.26  ? 201 PHE B CD2   1 
ATOM   3233  C  CE1   . PHE B 1 201 ? 199.135 224.764 182.057 1.00 16.50  ? 201 PHE B CE1   1 
ATOM   3234  C  CE2   . PHE B 1 201 ? 197.459 226.440 182.253 1.00 17.75  ? 201 PHE B CE2   1 
ATOM   3235  C  CZ    . PHE B 1 201 ? 197.932 225.194 182.566 1.00 16.74  ? 201 PHE B CZ    1 
ATOM   3236  N  N     . GLY B 1 202 ? 198.995 229.037 177.336 1.00 30.27  ? 202 GLY B N     1 
ATOM   3237  C  CA    . GLY B 1 202 ? 198.862 230.204 176.487 1.00 37.22  ? 202 GLY B CA    1 
ATOM   3238  C  C     . GLY B 1 202 ? 199.293 231.482 177.201 1.00 44.25  ? 202 GLY B C     1 
ATOM   3239  O  O     . GLY B 1 202 ? 198.584 232.480 177.162 1.00 46.27  ? 202 GLY B O     1 
ATOM   3240  N  N     . THR B 1 203 ? 200.481 231.461 177.811 1.00 55.87  ? 203 THR B N     1 
ATOM   3241  C  CA    . THR B 1 203 ? 201.074 232.652 178.386 1.00 67.56  ? 203 THR B CA    1 
ATOM   3242  C  C     . THR B 1 203 ? 201.611 233.532 177.267 1.00 80.97  ? 203 THR B C     1 
ATOM   3243  O  O     . THR B 1 203 ? 201.816 233.065 176.147 1.00 82.91  ? 203 THR B O     1 
ATOM   3244  C  CB    . THR B 1 203 ? 202.177 232.268 179.365 1.00 66.87  ? 203 THR B CB    1 
ATOM   3245  O  OG1   . THR B 1 203 ? 203.118 231.436 178.693 1.00 66.53  ? 203 THR B OG1   1 
ATOM   3246  C  CG2   . THR B 1 203 ? 201.600 231.586 180.589 1.00 64.43  ? 203 THR B CG2   1 
ATOM   3247  N  N     . PRO B 1 204 ? 201.808 234.843 177.522 1.00 97.99  ? 204 PRO B N     1 
ATOM   3248  C  CA    . PRO B 1 204 ? 202.333 235.734 176.488 1.00 107.03 ? 204 PRO B CA    1 
ATOM   3249  C  C     . PRO B 1 204 ? 203.649 235.278 175.861 1.00 109.91 ? 204 PRO B C     1 
ATOM   3250  O  O     . PRO B 1 204 ? 203.897 235.567 174.696 1.00 112.46 ? 204 PRO B O     1 
ATOM   3251  C  CB    . PRO B 1 204 ? 202.481 237.082 177.204 1.00 108.63 ? 204 PRO B CB    1 
ATOM   3252  C  CG    . PRO B 1 204 ? 202.408 236.760 178.686 1.00 107.05 ? 204 PRO B CG    1 
ATOM   3253  C  CD    . PRO B 1 204 ? 201.493 235.555 178.776 1.00 101.66 ? 204 PRO B CD    1 
ATOM   3254  N  N     . LEU B 1 205 ? 204.478 234.558 176.622 1.00 109.60 ? 205 LEU B N     1 
ATOM   3255  C  CA    . LEU B 1 205 ? 205.741 234.076 176.081 1.00 112.25 ? 205 LEU B CA    1 
ATOM   3256  C  C     . LEU B 1 205 ? 205.485 233.044 174.982 1.00 110.98 ? 205 LEU B C     1 
ATOM   3257  O  O     . LEU B 1 205 ? 206.147 233.048 173.942 1.00 112.43 ? 205 LEU B O     1 
ATOM   3258  C  CB    . LEU B 1 205 ? 206.655 233.530 177.180 1.00 114.63 ? 205 LEU B CB    1 
ATOM   3259  C  CG    . LEU B 1 205 ? 206.201 232.282 177.948 1.00 116.42 ? 205 LEU B CG    1 
ATOM   3260  C  CD1   . LEU B 1 205 ? 206.749 230.994 177.349 1.00 115.68 ? 205 LEU B CD1   1 
ATOM   3261  C  CD2   . LEU B 1 205 ? 206.605 232.375 179.419 1.00 117.10 ? 205 LEU B CD2   1 
ATOM   3262  N  N     . LEU B 1 206 ? 204.514 232.154 175.207 1.00 108.41 ? 206 LEU B N     1 
ATOM   3263  C  CA    . LEU B 1 206 ? 204.253 231.080 174.255 1.00 104.62 ? 206 LEU B CA    1 
ATOM   3264  C  C     . LEU B 1 206 ? 203.386 231.573 173.099 1.00 108.91 ? 206 LEU B C     1 
ATOM   3265  O  O     . LEU B 1 206 ? 203.570 231.130 171.967 1.00 110.91 ? 206 LEU B O     1 
ATOM   3266  C  CB    . LEU B 1 206 ? 203.602 229.890 174.942 1.00 98.11  ? 206 LEU B CB    1 
ATOM   3267  C  CG    . LEU B 1 206 ? 203.944 228.515 174.361 1.00 92.11  ? 206 LEU B CG    1 
ATOM   3268  C  CD1   . LEU B 1 206 ? 205.416 228.240 174.581 1.00 93.44  ? 206 LEU B CD1   1 
ATOM   3269  C  CD2   . LEU B 1 206 ? 203.114 227.409 174.981 1.00 90.44  ? 206 LEU B CD2   1 
ATOM   3270  N  N     . THR B 1 207 ? 202.461 232.504 173.366 1.00 115.48 ? 207 THR B N     1 
ATOM   3271  C  CA    . THR B 1 207 ? 201.641 233.052 172.296 1.00 124.56 ? 207 THR B CA    1 
ATOM   3272  C  C     . THR B 1 207 ? 202.463 233.947 171.369 1.00 132.13 ? 207 THR B C     1 
ATOM   3273  O  O     . THR B 1 207 ? 202.018 234.234 170.261 1.00 133.53 ? 207 THR B O     1 
ATOM   3274  C  CB    . THR B 1 207 ? 200.432 233.791 172.859 1.00 128.93 ? 207 THR B CB    1 
ATOM   3275  O  OG1   . THR B 1 207 ? 200.879 234.759 173.798 1.00 132.71 ? 207 THR B OG1   1 
ATOM   3276  C  CG2   . THR B 1 207 ? 199.463 232.834 173.519 1.00 127.78 ? 207 THR B CG2   1 
ATOM   3277  N  N     . SER B 1 208 ? 203.625 234.422 171.830 1.00 140.81 ? 208 SER B N     1 
ATOM   3278  C  CA    . SER B 1 208 ? 204.518 235.223 171.003 1.00 149.96 ? 208 SER B CA    1 
ATOM   3279  C  C     . SER B 1 208 ? 205.510 234.356 170.228 1.00 154.41 ? 208 SER B C     1 
ATOM   3280  O  O     . SER B 1 208 ? 206.191 234.864 169.335 1.00 158.23 ? 208 SER B O     1 
ATOM   3281  C  CB    . SER B 1 208 ? 205.256 236.253 171.841 1.00 152.48 ? 208 SER B CB    1 
ATOM   3282  O  OG    . SER B 1 208 ? 204.341 237.053 172.577 1.00 155.70 ? 208 SER B OG    1 
ATOM   3283  N  N     . LEU B 1 209 ? 205.615 233.066 170.568 1.00 151.18 ? 209 LEU B N     1 
ATOM   3284  C  CA    . LEU B 1 209 ? 206.458 232.146 169.823 1.00 145.38 ? 209 LEU B CA    1 
ATOM   3285  C  C     . LEU B 1 209 ? 205.916 231.948 168.414 1.00 138.85 ? 209 LEU B C     1 
ATOM   3286  O  O     . LEU B 1 209 ? 204.742 232.204 168.163 1.00 133.62 ? 209 LEU B O     1 
ATOM   3287  C  CB    . LEU B 1 209 ? 206.564 230.812 170.563 1.00 147.68 ? 209 LEU B CB    1 
ATOM   3288  C  CG    . LEU B 1 209 ? 207.632 230.728 171.659 1.00 151.77 ? 209 LEU B CG    1 
ATOM   3289  C  CD1   . LEU B 1 209 ? 207.848 229.275 172.069 1.00 150.85 ? 209 LEU B CD1   1 
ATOM   3290  C  CD2   . LEU B 1 209 ? 208.957 231.346 171.226 1.00 151.14 ? 209 LEU B CD2   1 
ATOM   3291  N  N     . PRO B 1 210 ? 206.764 231.521 167.455 1.00 133.43 ? 210 PRO B N     1 
ATOM   3292  C  CA    . PRO B 1 210 ? 206.312 231.355 166.077 1.00 128.98 ? 210 PRO B CA    1 
ATOM   3293  C  C     . PRO B 1 210 ? 205.123 230.407 165.982 1.00 123.46 ? 210 PRO B C     1 
ATOM   3294  O  O     . PRO B 1 210 ? 205.057 229.399 166.683 1.00 121.71 ? 210 PRO B O     1 
ATOM   3295  C  CB    . PRO B 1 210 ? 207.539 230.819 165.333 1.00 130.05 ? 210 PRO B CB    1 
ATOM   3296  C  CG    . PRO B 1 210 ? 208.464 230.321 166.422 1.00 128.31 ? 210 PRO B CG    1 
ATOM   3297  C  CD    . PRO B 1 210 ? 208.198 231.223 167.614 1.00 130.67 ? 210 PRO B CD    1 
ATOM   3298  N  N     . GLU B 1 211 ? 204.198 230.735 165.077 1.00 121.11 ? 211 GLU B N     1 
ATOM   3299  C  CA    . GLU B 1 211 ? 202.967 229.979 164.941 1.00 121.80 ? 211 GLU B CA    1 
ATOM   3300  C  C     . GLU B 1 211 ? 203.261 228.543 164.515 1.00 118.79 ? 211 GLU B C     1 
ATOM   3301  O  O     . GLU B 1 211 ? 202.486 227.640 164.822 1.00 119.43 ? 211 GLU B O     1 
ATOM   3302  C  CB    . GLU B 1 211 ? 202.045 230.680 163.941 1.00 125.29 ? 211 GLU B CB    1 
ATOM   3303  C  CG    . GLU B 1 211 ? 200.678 230.022 163.782 1.00 129.01 ? 211 GLU B CG    1 
ATOM   3304  C  CD    . GLU B 1 211 ? 199.749 230.201 164.975 1.00 136.32 ? 211 GLU B CD    1 
ATOM   3305  O  OE1   . GLU B 1 211 ? 199.979 229.546 166.017 1.00 139.26 ? 211 GLU B OE1   1 
ATOM   3306  O  OE2   . GLU B 1 211 ? 198.816 231.028 164.871 1.00 139.08 ? 211 GLU B OE2   1 
ATOM   3307  N  N     . LYS B 1 212 ? 204.351 228.314 163.780 1.00 114.76 ? 212 LYS B N     1 
ATOM   3308  C  CA    . LYS B 1 212 ? 204.697 226.976 163.330 1.00 114.36 ? 212 LYS B CA    1 
ATOM   3309  C  C     . LYS B 1 212 ? 205.004 226.074 164.527 1.00 105.01 ? 212 LYS B C     1 
ATOM   3310  O  O     . LYS B 1 212 ? 204.513 224.949 164.605 1.00 99.69  ? 212 LYS B O     1 
ATOM   3311  C  CB    . LYS B 1 212 ? 205.896 227.040 162.379 1.00 117.77 ? 212 LYS B CB    1 
ATOM   3312  C  CG    . LYS B 1 212 ? 206.216 225.762 161.635 1.00 119.03 ? 212 LYS B CG    1 
ATOM   3313  C  CD    . LYS B 1 212 ? 205.472 225.623 160.310 1.00 117.39 ? 212 LYS B CD    1 
ATOM   3314  C  CE    . LYS B 1 212 ? 205.939 224.448 159.515 1.00 115.30 ? 212 LYS B CE    1 
ATOM   3315  N  NZ    . LYS B 1 212 ? 205.095 224.208 158.342 1.00 112.23 ? 212 LYS B NZ    1 
ATOM   3316  N  N     . VAL B 1 213 ? 205.826 226.566 165.451 1.00 96.86  ? 213 VAL B N     1 
ATOM   3317  C  CA    . VAL B 1 213 ? 206.169 225.795 166.635 1.00 92.58  ? 213 VAL B CA    1 
ATOM   3318  C  C     . VAL B 1 213 ? 204.952 225.716 167.557 1.00 89.76  ? 213 VAL B C     1 
ATOM   3319  O  O     . VAL B 1 213 ? 204.689 224.680 168.165 1.00 85.79  ? 213 VAL B O     1 
ATOM   3320  C  CB    . VAL B 1 213 ? 207.395 226.379 167.357 1.00 91.04  ? 213 VAL B CB    1 
ATOM   3321  C  CG1   . VAL B 1 213 ? 207.758 225.566 168.586 1.00 89.53  ? 213 VAL B CG1   1 
ATOM   3322  C  CG2   . VAL B 1 213 ? 208.610 226.469 166.445 1.00 88.94  ? 213 VAL B CG2   1 
ATOM   3323  N  N     . CYS B 1 214 ? 204.204 226.815 167.673 1.00 90.07  ? 214 CYS B N     1 
ATOM   3324  C  CA    . CYS B 1 214 ? 203.093 226.909 168.608 1.00 87.60  ? 214 CYS B CA    1 
ATOM   3325  C  C     . CYS B 1 214 ? 201.987 225.920 168.239 1.00 76.81  ? 214 CYS B C     1 
ATOM   3326  O  O     . CYS B 1 214 ? 201.463 225.224 169.110 1.00 76.44  ? 214 CYS B O     1 
ATOM   3327  C  CB    . CYS B 1 214 ? 202.558 228.337 168.640 1.00 98.95  ? 214 CYS B CB    1 
ATOM   3328  S  SG    . CYS B 1 214 ? 201.119 228.568 169.719 1.00 106.31 ? 214 CYS B SG    1 
ATOM   3329  N  N     . ASN B 1 215 ? 201.617 225.868 166.952 1.00 71.39  ? 215 ASN B N     1 
ATOM   3330  C  CA    . ASN B 1 215 ? 200.565 224.963 166.515 1.00 65.51  ? 215 ASN B CA    1 
ATOM   3331  C  C     . ASN B 1 215 ? 200.993 223.509 166.715 1.00 52.15  ? 215 ASN B C     1 
ATOM   3332  O  O     . ASN B 1 215 ? 200.183 222.670 167.101 1.00 49.90  ? 215 ASN B O     1 
ATOM   3333  C  CB    . ASN B 1 215 ? 200.183 225.205 165.059 1.00 73.32  ? 215 ASN B CB    1 
ATOM   3334  C  CG    . ASN B 1 215 ? 199.256 226.383 164.897 1.00 82.37  ? 215 ASN B CG    1 
ATOM   3335  O  OD1   . ASN B 1 215 ? 198.424 226.634 165.774 1.00 87.41  ? 215 ASN B OD1   1 
ATOM   3336  N  ND2   . ASN B 1 215 ? 199.362 227.095 163.782 1.00 89.65  ? 215 ASN B ND2   1 
ATOM   3337  N  N     . PHE B 1 216 ? 202.260 223.210 166.425 1.00 43.17  ? 216 PHE B N     1 
ATOM   3338  C  CA    . PHE B 1 216 ? 202.745 221.852 166.578 1.00 40.67  ? 216 PHE B CA    1 
ATOM   3339  C  C     . PHE B 1 216 ? 202.709 221.424 168.049 1.00 38.13  ? 216 PHE B C     1 
ATOM   3340  O  O     . PHE B 1 216 ? 202.257 220.334 168.369 1.00 34.68  ? 216 PHE B O     1 
ATOM   3341  C  CB    . PHE B 1 216 ? 204.151 221.724 166.001 1.00 35.52  ? 216 PHE B CB    1 
ATOM   3342  C  CG    . PHE B 1 216 ? 204.824 220.433 166.403 1.00 33.52  ? 216 PHE B CG    1 
ATOM   3343  C  CD1   . PHE B 1 216 ? 204.421 219.228 165.848 1.00 33.43  ? 216 PHE B CD1   1 
ATOM   3344  C  CD2   . PHE B 1 216 ? 205.854 220.439 167.336 1.00 33.36  ? 216 PHE B CD2   1 
ATOM   3345  C  CE1   . PHE B 1 216 ? 205.057 218.051 166.205 1.00 34.95  ? 216 PHE B CE1   1 
ATOM   3346  C  CE2   . PHE B 1 216 ? 206.463 219.258 167.707 1.00 33.79  ? 216 PHE B CE2   1 
ATOM   3347  C  CZ    . PHE B 1 216 ? 206.071 218.067 167.143 1.00 34.20  ? 216 PHE B CZ    1 
ATOM   3348  N  N     . LEU B 1 217 ? 203.195 222.285 168.940 1.00 37.64  ? 217 LEU B N     1 
ATOM   3349  C  CA    . LEU B 1 217 ? 203.239 221.944 170.358 1.00 40.15  ? 217 LEU B CA    1 
ATOM   3350  C  C     . LEU B 1 217 ? 201.826 221.786 170.914 1.00 36.72  ? 217 LEU B C     1 
ATOM   3351  O  O     . LEU B 1 217 ? 201.577 220.883 171.709 1.00 36.10  ? 217 LEU B O     1 
ATOM   3352  C  CB    . LEU B 1 217 ? 204.015 222.995 171.148 1.00 40.82  ? 217 LEU B CB    1 
ATOM   3353  C  CG    . LEU B 1 217 ? 205.531 223.001 170.944 1.00 41.84  ? 217 LEU B CG    1 
ATOM   3354  C  CD1   . LEU B 1 217 ? 206.130 224.173 171.690 1.00 42.96  ? 217 LEU B CD1   1 
ATOM   3355  C  CD2   . LEU B 1 217 ? 206.191 221.700 171.368 1.00 43.54  ? 217 LEU B CD2   1 
ATOM   3356  N  N     . ALA B 1 218 ? 200.898 222.650 170.478 1.00 33.71  ? 218 ALA B N     1 
ATOM   3357  C  CA    . ALA B 1 218 ? 199.510 222.533 170.909 1.00 33.86  ? 218 ALA B CA    1 
ATOM   3358  C  C     . ALA B 1 218 ? 198.913 221.201 170.455 1.00 34.88  ? 218 ALA B C     1 
ATOM   3359  O  O     . ALA B 1 218 ? 198.175 220.558 171.198 1.00 32.90  ? 218 ALA B O     1 
ATOM   3360  C  CB    . ALA B 1 218 ? 198.698 223.698 170.402 1.00 36.01  ? 218 ALA B CB    1 
ATOM   3361  N  N     . SER B 1 219 ? 199.255 220.779 169.230 1.00 31.30  ? 219 SER B N     1 
ATOM   3362  C  CA    . SER B 1 219 ? 198.791 219.504 168.709 1.00 31.35  ? 219 SER B CA    1 
ATOM   3363  C  C     . SER B 1 219 ? 199.445 218.328 169.436 1.00 29.78  ? 219 SER B C     1 
ATOM   3364  O  O     . SER B 1 219 ? 198.945 217.212 169.373 1.00 29.06  ? 219 SER B O     1 
ATOM   3365  C  CB    . SER B 1 219 ? 199.030 219.411 167.220 1.00 32.44  ? 219 SER B CB    1 
ATOM   3366  O  OG    . SER B 1 219 ? 200.414 219.288 166.930 1.00 31.81  ? 219 SER B OG    1 
ATOM   3367  N  N     . GLN B 1 220 ? 200.575 218.564 170.112 1.00 29.71  ? 220 GLN B N     1 
ATOM   3368  C  CA    . GLN B 1 220 ? 201.272 217.493 170.808 1.00 31.62  ? 220 GLN B CA    1 
ATOM   3369  C  C     . GLN B 1 220 ? 200.684 217.193 172.182 1.00 27.37  ? 220 GLN B C     1 
ATOM   3370  O  O     . GLN B 1 220 ? 201.040 216.177 172.767 1.00 27.48  ? 220 GLN B O     1 
ATOM   3371  C  CB    . GLN B 1 220 ? 202.754 217.826 170.965 1.00 36.27  ? 220 GLN B CB    1 
ATOM   3372  C  CG    . GLN B 1 220 ? 203.543 217.726 169.668 1.00 40.03  ? 220 GLN B CG    1 
ATOM   3373  C  CD    . GLN B 1 220 ? 203.306 216.436 168.915 1.00 43.01  ? 220 GLN B CD    1 
ATOM   3374  O  OE1   . GLN B 1 220 ? 202.390 216.338 168.089 1.00 43.24  ? 220 GLN B OE1   1 
ATOM   3375  N  NE2   . GLN B 1 220 ? 204.132 215.438 169.203 1.00 49.25  ? 220 GLN B NE2   1 
ATOM   3376  N  N     . VAL B 1 221 ? 199.801 218.048 172.696 1.00 23.74  ? 221 VAL B N     1 
ATOM   3377  C  CA    . VAL B 1 221 ? 199.126 217.743 173.946 1.00 22.35  ? 221 VAL B CA    1 
ATOM   3378  C  C     . VAL B 1 221 ? 198.092 216.660 173.677 1.00 21.34  ? 221 VAL B C     1 
ATOM   3379  O  O     . VAL B 1 221 ? 197.223 216.836 172.830 1.00 21.66  ? 221 VAL B O     1 
ATOM   3380  C  CB    . VAL B 1 221 ? 198.478 218.994 174.551 1.00 22.36  ? 221 VAL B CB    1 
ATOM   3381  C  CG1   . VAL B 1 221 ? 197.894 218.700 175.929 1.00 21.83  ? 221 VAL B CG1   1 
ATOM   3382  C  CG2   . VAL B 1 221 ? 199.472 220.149 174.613 1.00 21.85  ? 221 VAL B CG2   1 
ATOM   3383  N  N     . PRO B 1 222 ? 198.162 215.489 174.355 1.00 20.77  ? 222 PRO B N     1 
ATOM   3384  C  CA    . PRO B 1 222 ? 197.209 214.409 174.101 1.00 20.14  ? 222 PRO B CA    1 
ATOM   3385  C  C     . PRO B 1 222 ? 195.753 214.845 174.179 1.00 20.24  ? 222 PRO B C     1 
ATOM   3386  O  O     . PRO B 1 222 ? 195.016 214.686 173.213 1.00 21.03  ? 222 PRO B O     1 
ATOM   3387  C  CB    . PRO B 1 222 ? 197.560 213.368 175.168 1.00 20.51  ? 222 PRO B CB    1 
ATOM   3388  C  CG    . PRO B 1 222 ? 199.023 213.609 175.392 1.00 20.77  ? 222 PRO B CG    1 
ATOM   3389  C  CD    . PRO B 1 222 ? 199.204 215.109 175.321 1.00 20.07  ? 222 PRO B CD    1 
ATOM   3390  N  N     . PHE B 1 223 ? 195.340 215.383 175.332 1.00 18.88  ? 223 PHE B N     1 
ATOM   3391  C  CA    . PHE B 1 223 ? 193.988 215.908 175.442 1.00 18.99  ? 223 PHE B CA    1 
ATOM   3392  C  C     . PHE B 1 223 ? 193.891 216.836 176.651 1.00 20.04  ? 223 PHE B C     1 
ATOM   3393  O  O     . PHE B 1 223 ? 194.319 216.477 177.748 1.00 20.14  ? 223 PHE B O     1 
ATOM   3394  C  CB    . PHE B 1 223 ? 192.938 214.794 175.564 1.00 18.44  ? 223 PHE B CB    1 
ATOM   3395  C  CG    . PHE B 1 223 ? 191.526 215.348 175.583 1.00 20.85  ? 223 PHE B CG    1 
ATOM   3396  C  CD1   . PHE B 1 223 ? 190.907 215.749 174.402 1.00 21.52  ? 223 PHE B CD1   1 
ATOM   3397  C  CD2   . PHE B 1 223 ? 190.836 215.520 176.778 1.00 20.95  ? 223 PHE B CD2   1 
ATOM   3398  C  CE1   . PHE B 1 223 ? 189.645 216.326 174.427 1.00 22.11  ? 223 PHE B CE1   1 
ATOM   3399  C  CE2   . PHE B 1 223 ? 189.576 216.097 176.789 1.00 22.65  ? 223 PHE B CE2   1 
ATOM   3400  C  CZ    . PHE B 1 223 ? 188.990 216.514 175.617 1.00 22.51  ? 223 PHE B CZ    1 
ATOM   3401  N  N     . PRO B 1 224 ? 193.318 218.050 176.516 1.00 21.74  ? 224 PRO B N     1 
ATOM   3402  C  CA    . PRO B 1 224 ? 192.858 218.612 175.239 1.00 23.40  ? 224 PRO B CA    1 
ATOM   3403  C  C     . PRO B 1 224 ? 194.025 219.089 174.375 1.00 24.76  ? 224 PRO B C     1 
ATOM   3404  O  O     . PRO B 1 224 ? 194.997 219.621 174.898 1.00 25.56  ? 224 PRO B O     1 
ATOM   3405  C  CB    . PRO B 1 224 ? 191.939 219.776 175.663 1.00 23.61  ? 224 PRO B CB    1 
ATOM   3406  C  CG    . PRO B 1 224 ? 192.333 220.110 177.085 1.00 23.63  ? 224 PRO B CG    1 
ATOM   3407  C  CD    . PRO B 1 224 ? 193.151 218.976 177.636 1.00 22.74  ? 224 PRO B CD    1 
ATOM   3408  N  N     . SER B 1 225 ? 193.925 218.906 173.052 1.00 25.61  ? 225 SER B N     1 
ATOM   3409  C  CA    . SER B 1 225 ? 195.019 219.214 172.141 1.00 26.44  ? 225 SER B CA    1 
ATOM   3410  C  C     . SER B 1 225 ? 195.049 220.713 171.865 1.00 26.65  ? 225 SER B C     1 
ATOM   3411  O  O     . SER B 1 225 ? 194.718 221.178 170.775 1.00 28.69  ? 225 SER B O     1 
ATOM   3412  C  CB    . SER B 1 225 ? 194.920 218.415 170.868 1.00 25.98  ? 225 SER B CB    1 
ATOM   3413  O  OG    . SER B 1 225 ? 194.818 217.025 171.144 1.00 27.52  ? 225 SER B OG    1 
ATOM   3414  N  N     . ARG B 1 226 ? 195.441 221.464 172.892 1.00 25.46  ? 226 ARG B N     1 
ATOM   3415  C  CA    . ARG B 1 226 ? 195.559 222.905 172.792 1.00 26.02  ? 226 ARG B CA    1 
ATOM   3416  C  C     . ARG B 1 226 ? 196.401 223.384 173.958 1.00 24.39  ? 226 ARG B C     1 
ATOM   3417  O  O     . ARG B 1 226 ? 196.634 222.650 174.906 1.00 24.13  ? 226 ARG B O     1 
ATOM   3418  C  CB    . ARG B 1 226 ? 194.215 223.631 172.755 1.00 27.06  ? 226 ARG B CB    1 
ATOM   3419  C  CG    . ARG B 1 226 ? 193.210 223.091 173.756 1.00 29.48  ? 226 ARG B CG    1 
ATOM   3420  C  CD    . ARG B 1 226 ? 193.186 223.886 174.996 1.00 31.35  ? 226 ARG B CD    1 
ATOM   3421  N  NE    . ARG B 1 226 ? 192.043 223.567 175.864 1.00 32.72  ? 226 ARG B NE    1 
ATOM   3422  C  CZ    . ARG B 1 226 ? 191.966 223.929 177.145 1.00 32.13  ? 226 ARG B CZ    1 
ATOM   3423  N  NH1   . ARG B 1 226 ? 192.914 224.673 177.694 1.00 30.39  ? 226 ARG B NH1   1 
ATOM   3424  N  NH2   . ARG B 1 226 ? 190.941 223.542 177.886 1.00 32.31  ? 226 ARG B NH2   1 
ATOM   3425  N  N     . LEU B 1 227 ? 196.892 224.611 173.855 1.00 23.50  ? 227 LEU B N     1 
ATOM   3426  C  CA    . LEU B 1 227 ? 197.678 225.199 174.919 1.00 23.44  ? 227 LEU B CA    1 
ATOM   3427  C  C     . LEU B 1 227 ? 196.812 225.361 176.164 1.00 22.47  ? 227 LEU B C     1 
ATOM   3428  O  O     . LEU B 1 227 ? 195.613 225.642 176.096 1.00 21.54  ? 227 LEU B O     1 
ATOM   3429  C  CB    . LEU B 1 227 ? 198.249 226.541 174.462 1.00 25.02  ? 227 LEU B CB    1 
ATOM   3430  C  CG    . LEU B 1 227 ? 199.275 226.478 173.328 1.00 26.73  ? 227 LEU B CG    1 
ATOM   3431  C  CD1   . LEU B 1 227 ? 199.885 227.851 173.115 1.00 29.32  ? 227 LEU B CD1   1 
ATOM   3432  C  CD2   . LEU B 1 227 ? 200.357 225.448 173.585 1.00 27.39  ? 227 LEU B CD2   1 
ATOM   3433  N  N     . GLY B 1 228 ? 197.458 225.231 177.319 1.00 22.13  ? 228 GLY B N     1 
ATOM   3434  C  CA    . GLY B 1 228 ? 196.770 225.423 178.579 1.00 20.64  ? 228 GLY B CA    1 
ATOM   3435  C  C     . GLY B 1 228 ? 196.225 226.839 178.727 1.00 19.40  ? 228 GLY B C     1 
ATOM   3436  O  O     . GLY B 1 228 ? 196.906 227.817 178.459 1.00 20.56  ? 228 GLY B O     1 
ATOM   3437  N  N     . ASP B 1 229 ? 194.988 226.942 179.193 1.00 21.08  ? 229 ASP B N     1 
ATOM   3438  C  CA    . ASP B 1 229 ? 194.390 228.227 179.509 1.00 22.12  ? 229 ASP B CA    1 
ATOM   3439  C  C     . ASP B 1 229 ? 194.873 228.664 180.890 1.00 19.61  ? 229 ASP B C     1 
ATOM   3440  O  O     . ASP B 1 229 ? 194.797 227.905 181.858 1.00 19.85  ? 229 ASP B O     1 
ATOM   3441  C  CB    . ASP B 1 229 ? 192.880 228.120 179.491 1.00 25.54  ? 229 ASP B CB    1 
ATOM   3442  C  CG    . ASP B 1 229 ? 192.179 229.463 179.413 1.00 30.29  ? 229 ASP B CG    1 
ATOM   3443  O  OD1   . ASP B 1 229 ? 192.600 230.402 180.124 1.00 31.44  ? 229 ASP B OD1   1 
ATOM   3444  O  OD2   . ASP B 1 229 ? 191.169 229.544 178.678 1.00 35.38  ? 229 ASP B OD2   1 
ATOM   3445  N  N     . PRO B 1 230 ? 195.419 229.890 181.039 1.00 18.13  ? 230 PRO B N     1 
ATOM   3446  C  CA    . PRO B 1 230 ? 195.833 230.374 182.357 1.00 17.38  ? 230 PRO B CA    1 
ATOM   3447  C  C     . PRO B 1 230 ? 194.749 230.301 183.426 1.00 16.35  ? 230 PRO B C     1 
ATOM   3448  O  O     . PRO B 1 230 ? 195.078 230.148 184.596 1.00 15.99  ? 230 PRO B O     1 
ATOM   3449  C  CB    . PRO B 1 230 ? 196.274 231.812 182.081 1.00 18.13  ? 230 PRO B CB    1 
ATOM   3450  C  CG    . PRO B 1 230 ? 196.774 231.747 180.663 1.00 18.34  ? 230 PRO B CG    1 
ATOM   3451  C  CD    . PRO B 1 230 ? 195.765 230.840 179.967 1.00 19.10  ? 230 PRO B CD    1 
ATOM   3452  N  N     . ALA B 1 231 ? 193.472 230.407 183.032 1.00 15.22  ? 231 ALA B N     1 
ATOM   3453  C  CA    . ALA B 1 231 ? 192.368 230.222 183.962 1.00 15.31  ? 231 ALA B CA    1 
ATOM   3454  C  C     . ALA B 1 231 ? 192.380 228.822 184.583 1.00 14.65  ? 231 ALA B C     1 
ATOM   3455  O  O     . ALA B 1 231 ? 191.992 228.656 185.736 1.00 13.89  ? 231 ALA B O     1 
ATOM   3456  C  CB    . ALA B 1 231 ? 191.049 230.493 183.281 1.00 16.09  ? 231 ALA B CB    1 
ATOM   3457  N  N     . GLU B 1 232 ? 192.832 227.818 183.821 1.00 14.17  ? 232 GLU B N     1 
ATOM   3458  C  CA    . GLU B 1 232 ? 192.921 226.468 184.338 1.00 14.19  ? 232 GLU B CA    1 
ATOM   3459  C  C     . GLU B 1 232 ? 193.994 226.363 185.415 1.00 12.08  ? 232 GLU B C     1 
ATOM   3460  O  O     . GLU B 1 232 ? 193.827 225.631 186.387 1.00 11.63  ? 232 GLU B O     1 
ATOM   3461  C  CB    . GLU B 1 232 ? 193.195 225.486 183.202 1.00 16.58  ? 232 GLU B CB    1 
ATOM   3462  C  CG    . GLU B 1 232 ? 191.992 225.361 182.274 1.00 19.24  ? 232 GLU B CG    1 
ATOM   3463  C  CD    . GLU B 1 232 ? 192.362 224.922 180.883 1.00 22.08  ? 232 GLU B CD    1 
ATOM   3464  O  OE1   . GLU B 1 232 ? 193.576 224.781 180.614 1.00 23.06  ? 232 GLU B OE1   1 
ATOM   3465  O  OE2   . GLU B 1 232 ? 191.441 224.784 180.051 1.00 25.84  ? 232 GLU B OE2   1 
ATOM   3466  N  N     . TYR B 1 233 ? 195.098 227.094 185.242 1.00 10.61  ? 233 TYR B N     1 
ATOM   3467  C  CA    . TYR B 1 233 ? 196.100 227.187 186.289 1.00 10.04  ? 233 TYR B CA    1 
ATOM   3468  C  C     . TYR B 1 233 ? 195.487 227.819 187.534 1.00 8.61   ? 233 TYR B C     1 
ATOM   3469  O  O     . TYR B 1 233 ? 195.725 227.357 188.648 1.00 8.29   ? 233 TYR B O     1 
ATOM   3470  C  CB    . TYR B 1 233 ? 197.324 227.964 185.797 1.00 10.18  ? 233 TYR B CB    1 
ATOM   3471  C  CG    . TYR B 1 233 ? 198.363 228.220 186.871 1.00 10.61  ? 233 TYR B CG    1 
ATOM   3472  C  CD1   . TYR B 1 233 ? 199.412 227.340 187.071 1.00 11.14  ? 233 TYR B CD1   1 
ATOM   3473  C  CD2   . TYR B 1 233 ? 198.304 229.355 187.669 1.00 11.33  ? 233 TYR B CD2   1 
ATOM   3474  C  CE1   . TYR B 1 233 ? 200.380 227.577 188.038 1.00 10.91  ? 233 TYR B CE1   1 
ATOM   3475  C  CE2   . TYR B 1 233 ? 199.254 229.600 188.648 1.00 11.62  ? 233 TYR B CE2   1 
ATOM   3476  C  CZ    . TYR B 1 233 ? 200.292 228.708 188.828 1.00 11.43  ? 233 TYR B CZ    1 
ATOM   3477  O  OH    . TYR B 1 233 ? 201.224 228.951 189.794 1.00 12.58  ? 233 TYR B OH    1 
ATOM   3478  N  N     . ALA B 1 234 ? 194.731 228.904 187.346 1.00 8.19   ? 234 ALA B N     1 
ATOM   3479  C  CA    . ALA B 1 234 ? 194.110 229.607 188.458 1.00 8.13   ? 234 ALA B CA    1 
ATOM   3480  C  C     . ALA B 1 234 ? 193.141 228.694 189.201 1.00 8.18   ? 234 ALA B C     1 
ATOM   3481  O  O     . ALA B 1 234 ? 193.073 228.721 190.423 1.00 7.87   ? 234 ALA B O     1 
ATOM   3482  C  CB    . ALA B 1 234 ? 193.405 230.871 187.971 1.00 8.02   ? 234 ALA B CB    1 
ATOM   3483  N  N     . HIS B 1 235 ? 192.384 227.889 188.455 1.00 8.60   ? 235 HIS B N     1 
ATOM   3484  C  CA    . HIS B 1 235 ? 191.448 226.955 189.061 1.00 8.91   ? 235 HIS B CA    1 
ATOM   3485  C  C     . HIS B 1 235 ? 192.180 225.956 189.956 1.00 8.07   ? 235 HIS B C     1 
ATOM   3486  O  O     . HIS B 1 235 ? 191.716 225.650 191.047 1.00 8.09   ? 235 HIS B O     1 
ATOM   3487  C  CB    . HIS B 1 235 ? 190.651 226.240 187.966 1.00 10.31  ? 235 HIS B CB    1 
ATOM   3488  C  CG    . HIS B 1 235 ? 189.704 225.215 188.484 1.00 11.65  ? 235 HIS B CG    1 
ATOM   3489  N  ND1   . HIS B 1 235 ? 190.094 223.915 188.742 1.00 12.08  ? 235 HIS B ND1   1 
ATOM   3490  C  CD2   . HIS B 1 235 ? 188.392 225.310 188.840 1.00 13.26  ? 235 HIS B CD2   1 
ATOM   3491  C  CE1   . HIS B 1 235 ? 189.056 223.244 189.217 1.00 12.61  ? 235 HIS B CE1   1 
ATOM   3492  N  NE2   . HIS B 1 235 ? 188.012 224.059 189.278 1.00 12.53  ? 235 HIS B NE2   1 
ATOM   3493  N  N     . LEU B 1 236 ? 193.314 225.426 189.497 1.00 7.24   ? 236 LEU B N     1 
ATOM   3494  C  CA    . LEU B 1 236 ? 194.085 224.492 190.298 1.00 7.14   ? 236 LEU B CA    1 
ATOM   3495  C  C     . LEU B 1 236 ? 194.631 225.182 191.548 1.00 6.95   ? 236 LEU B C     1 
ATOM   3496  O  O     . LEU B 1 236 ? 194.681 224.579 192.611 1.00 6.79   ? 236 LEU B O     1 
ATOM   3497  C  CB    . LEU B 1 236 ? 195.206 223.864 189.471 1.00 7.36   ? 236 LEU B CB    1 
ATOM   3498  C  CG    . LEU B 1 236 ? 196.125 222.887 190.197 1.00 7.69   ? 236 LEU B CG    1 
ATOM   3499  C  CD1   . LEU B 1 236 ? 195.327 221.767 190.844 1.00 7.92   ? 236 LEU B CD1   1 
ATOM   3500  C  CD2   . LEU B 1 236 ? 197.183 222.334 189.257 1.00 7.99   ? 236 LEU B CD2   1 
ATOM   3501  N  N     . VAL B 1 237 ? 195.074 226.432 191.418 1.00 7.00   ? 237 VAL B N     1 
ATOM   3502  C  CA    . VAL B 1 237 ? 195.562 227.181 192.562 1.00 7.17   ? 237 VAL B CA    1 
ATOM   3503  C  C     . VAL B 1 237 ? 194.473 227.273 193.625 1.00 7.34   ? 237 VAL B C     1 
ATOM   3504  O  O     . VAL B 1 237 ? 194.722 227.050 194.806 1.00 7.00   ? 237 VAL B O     1 
ATOM   3505  C  CB    . VAL B 1 237 ? 196.073 228.576 192.151 1.00 7.22   ? 237 VAL B CB    1 
ATOM   3506  C  CG1   . VAL B 1 237 ? 196.212 229.488 193.360 1.00 7.28   ? 237 VAL B CG1   1 
ATOM   3507  C  CG2   . VAL B 1 237 ? 197.386 228.474 191.403 1.00 7.14   ? 237 VAL B CG2   1 
ATOM   3508  N  N     . GLN B 1 238 ? 193.253 227.625 193.213 1.00 7.74   ? 238 GLN B N     1 
ATOM   3509  C  CA    . GLN B 1 238 ? 192.150 227.699 194.150 1.00 8.46   ? 238 GLN B CA    1 
ATOM   3510  C  C     . GLN B 1 238 ? 191.864 226.345 194.802 1.00 7.94   ? 238 GLN B C     1 
ATOM   3511  O  O     . GLN B 1 238 ? 191.617 226.272 196.001 1.00 7.55   ? 238 GLN B O     1 
ATOM   3512  C  CB    . GLN B 1 238 ? 190.900 228.225 193.453 1.00 9.95   ? 238 GLN B CB    1 
ATOM   3513  C  CG    . GLN B 1 238 ? 189.702 228.349 194.389 1.00 11.84  ? 238 GLN B CG    1 
ATOM   3514  C  CD    . GLN B 1 238 ? 188.516 229.011 193.739 1.00 13.71  ? 238 GLN B CD    1 
ATOM   3515  O  OE1   . GLN B 1 238 ? 188.601 229.509 192.614 1.00 14.82  ? 238 GLN B OE1   1 
ATOM   3516  N  NE2   . GLN B 1 238 ? 187.426 229.067 194.487 1.00 14.89  ? 238 GLN B NE2   1 
ATOM   3517  N  N     . ALA B 1 239 ? 191.903 225.266 194.012 1.00 7.84   ? 239 ALA B N     1 
ATOM   3518  C  CA    . ALA B 1 239 ? 191.682 223.935 194.548 1.00 7.95   ? 239 ALA B CA    1 
ATOM   3519  C  C     . ALA B 1 239 ? 192.719 223.608 195.621 1.00 7.86   ? 239 ALA B C     1 
ATOM   3520  O  O     . ALA B 1 239 ? 192.383 223.009 196.638 1.00 8.44   ? 239 ALA B O     1 
ATOM   3521  C  CB    . ALA B 1 239 ? 191.686 222.915 193.445 1.00 8.29   ? 239 ALA B CB    1 
ATOM   3522  N  N     . ILE B 1 240 ? 193.981 223.995 195.400 1.00 7.37   ? 240 ILE B N     1 
ATOM   3523  C  CA    . ILE B 1 240 ? 195.021 223.756 196.380 1.00 7.64   ? 240 ILE B CA    1 
ATOM   3524  C  C     . ILE B 1 240 ? 194.751 224.544 197.657 1.00 7.62   ? 240 ILE B C     1 
ATOM   3525  O  O     . ILE B 1 240 ? 194.903 224.020 198.765 1.00 7.87   ? 240 ILE B O     1 
ATOM   3526  C  CB    . ILE B 1 240 ? 196.410 224.057 195.797 1.00 7.59   ? 240 ILE B CB    1 
ATOM   3527  C  CG1   . ILE B 1 240 ? 196.776 223.064 194.705 1.00 7.83   ? 240 ILE B CG1   1 
ATOM   3528  C  CG2   . ILE B 1 240 ? 197.460 224.070 196.904 1.00 7.57   ? 240 ILE B CG2   1 
ATOM   3529  C  CD1   . ILE B 1 240 ? 197.978 223.491 193.887 1.00 7.92   ? 240 ILE B CD1   1 
ATOM   3530  N  N     . ILE B 1 241 ? 194.343 225.799 197.509 1.00 8.29   ? 241 ILE B N     1 
ATOM   3531  C  CA    . ILE B 1 241 ? 194.055 226.631 198.667 1.00 9.00   ? 241 ILE B CA    1 
ATOM   3532  C  C     . ILE B 1 241 ? 192.899 226.035 199.473 1.00 9.89   ? 241 ILE B C     1 
ATOM   3533  O  O     . ILE B 1 241 ? 192.967 225.985 200.704 1.00 10.06  ? 241 ILE B O     1 
ATOM   3534  C  CB    . ILE B 1 241 ? 193.751 228.077 198.238 1.00 9.00   ? 241 ILE B CB    1 
ATOM   3535  C  CG1   . ILE B 1 241 ? 194.962 228.728 197.581 1.00 9.12   ? 241 ILE B CG1   1 
ATOM   3536  C  CG2   . ILE B 1 241 ? 193.257 228.896 199.427 1.00 9.16   ? 241 ILE B CG2   1 
ATOM   3537  C  CD1   . ILE B 1 241 ? 194.618 229.972 196.792 1.00 9.04   ? 241 ILE B CD1   1 
ATOM   3538  N  N     . GLU B 1 242 ? 191.853 225.570 198.794 1.00 10.76  ? 242 GLU B N     1 
ATOM   3539  C  CA    . GLU B 1 242 ? 190.663 225.091 199.478 1.00 12.92  ? 242 GLU B CA    1 
ATOM   3540  C  C     . GLU B 1 242 ? 190.864 223.715 200.111 1.00 13.08  ? 242 GLU B C     1 
ATOM   3541  O  O     . GLU B 1 242 ? 190.225 223.407 201.112 1.00 15.18  ? 242 GLU B O     1 
ATOM   3542  C  CB    . GLU B 1 242 ? 189.480 225.008 198.518 1.00 15.32  ? 242 GLU B CB    1 
ATOM   3543  C  CG    . GLU B 1 242 ? 188.985 226.354 198.015 1.00 18.48  ? 242 GLU B CG    1 
ATOM   3544  C  CD    . GLU B 1 242 ? 187.977 226.174 196.874 1.00 23.57  ? 242 GLU B CD    1 
ATOM   3545  O  OE1   . GLU B 1 242 ? 187.547 227.231 196.370 1.00 28.38  ? 242 GLU B OE1   1 
ATOM   3546  O  OE2   . GLU B 1 242 ? 187.652 225.041 196.419 1.00 27.31  ? 242 GLU B OE2   1 
ATOM   3547  N  N     . ASN B 1 243 ? 191.761 222.889 199.564 1.00 12.22  ? 243 ASN B N     1 
ATOM   3548  C  CA    . ASN B 1 243 ? 191.915 221.525 200.040 1.00 11.97  ? 243 ASN B CA    1 
ATOM   3549  C  C     . ASN B 1 243 ? 192.950 221.498 201.151 1.00 11.96  ? 243 ASN B C     1 
ATOM   3550  O  O     . ASN B 1 243 ? 194.127 221.717 200.888 1.00 13.34  ? 243 ASN B O     1 
ATOM   3551  C  CB    . ASN B 1 243 ? 192.329 220.584 198.913 1.00 11.93  ? 243 ASN B CB    1 
ATOM   3552  C  CG    . ASN B 1 243 ? 192.084 219.135 199.249 1.00 11.98  ? 243 ASN B CG    1 
ATOM   3553  O  OD1   . ASN B 1 243 ? 192.622 218.628 200.230 1.00 11.73  ? 243 ASN B OD1   1 
ATOM   3554  N  ND2   . ASN B 1 243 ? 191.288 218.447 198.446 1.00 11.70  ? 243 ASN B ND2   1 
ATOM   3555  N  N     . PRO B 1 244 ? 192.567 221.264 202.421 1.00 11.96  ? 244 PRO B N     1 
ATOM   3556  C  CA    . PRO B 1 244 ? 193.516 221.343 203.528 1.00 11.82  ? 244 PRO B CA    1 
ATOM   3557  C  C     . PRO B 1 244 ? 194.569 220.238 203.579 1.00 11.11  ? 244 PRO B C     1 
ATOM   3558  O  O     . PRO B 1 244 ? 195.490 220.320 204.376 1.00 11.29  ? 244 PRO B O     1 
ATOM   3559  C  CB    . PRO B 1 244 ? 192.614 221.256 204.775 1.00 12.28  ? 244 PRO B CB    1 
ATOM   3560  C  CG    . PRO B 1 244 ? 191.218 221.452 204.264 1.00 13.24  ? 244 PRO B CG    1 
ATOM   3561  C  CD    . PRO B 1 244 ? 191.209 220.922 202.870 1.00 12.46  ? 244 PRO B CD    1 
ATOM   3562  N  N     . PHE B 1 245 ? 194.426 219.195 202.755 1.00 10.22  ? 245 PHE B N     1 
ATOM   3563  C  CA    . PHE B 1 245 ? 195.260 218.025 202.920 1.00 9.66   ? 245 PHE B CA    1 
ATOM   3564  C  C     . PHE B 1 245 ? 196.284 217.848 201.807 1.00 9.02   ? 245 PHE B C     1 
ATOM   3565  O  O     . PHE B 1 245 ? 197.045 216.876 201.859 1.00 8.86   ? 245 PHE B O     1 
ATOM   3566  C  CB    . PHE B 1 245 ? 194.366 216.793 203.026 1.00 9.60   ? 245 PHE B CB    1 
ATOM   3567  C  CG    . PHE B 1 245 ? 194.998 215.700 203.856 1.00 9.37   ? 245 PHE B CG    1 
ATOM   3568  C  CD1   . PHE B 1 245 ? 195.197 215.873 205.216 1.00 9.31   ? 245 PHE B CD1   1 
ATOM   3569  C  CD2   . PHE B 1 245 ? 195.401 214.531 203.259 1.00 9.28   ? 245 PHE B CD2   1 
ATOM   3570  C  CE1   . PHE B 1 245 ? 195.736 214.850 205.985 1.00 9.53   ? 245 PHE B CE1   1 
ATOM   3571  C  CE2   . PHE B 1 245 ? 195.950 213.522 204.013 1.00 9.51   ? 245 PHE B CE2   1 
ATOM   3572  C  CZ    . PHE B 1 245 ? 196.117 213.672 205.376 1.00 9.42   ? 245 PHE B CZ    1 
ATOM   3573  N  N     . LEU B 1 246 ? 196.322 218.802 200.864 1.00 8.30   ? 246 LEU B N     1 
ATOM   3574  C  CA    . LEU B 1 246 ? 197.331 218.824 199.817 1.00 7.97   ? 246 LEU B CA    1 
ATOM   3575  C  C     . LEU B 1 246 ? 198.569 219.537 200.350 1.00 7.44   ? 246 LEU B C     1 
ATOM   3576  O  O     . LEU B 1 246 ? 198.514 220.723 200.652 1.00 7.67   ? 246 LEU B O     1 
ATOM   3577  C  CB    . LEU B 1 246 ? 196.803 219.548 198.575 1.00 8.04   ? 246 LEU B CB    1 
ATOM   3578  C  CG    . LEU B 1 246 ? 195.948 218.747 197.595 1.00 8.18   ? 246 LEU B CG    1 
ATOM   3579  C  CD1   . LEU B 1 246 ? 195.344 219.676 196.584 1.00 8.03   ? 246 LEU B CD1   1 
ATOM   3580  C  CD2   . LEU B 1 246 ? 196.761 217.657 196.901 1.00 8.05   ? 246 LEU B CD2   1 
ATOM   3581  N  N     . ASN B 1 247 ? 199.687 218.825 200.443 1.00 6.95   ? 247 ASN B N     1 
ATOM   3582  C  CA    . ASN B 1 247 ? 200.897 219.397 200.981 1.00 6.87   ? 247 ASN B CA    1 
ATOM   3583  C  C     . ASN B 1 247 ? 202.119 218.626 200.471 1.00 6.91   ? 247 ASN B C     1 
ATOM   3584  O  O     . ASN B 1 247 ? 202.095 217.407 200.328 1.00 7.04   ? 247 ASN B O     1 
ATOM   3585  C  CB    . ASN B 1 247 ? 200.847 219.368 202.500 1.00 6.63   ? 247 ASN B CB    1 
ATOM   3586  C  CG    . ASN B 1 247 ? 201.835 220.299 203.151 1.00 6.26   ? 247 ASN B CG    1 
ATOM   3587  O  OD1   . ASN B 1 247 ? 202.446 221.131 202.482 1.00 6.23   ? 247 ASN B OD1   1 
ATOM   3588  N  ND2   . ASN B 1 247 ? 201.974 220.183 204.460 1.00 6.07   ? 247 ASN B ND2   1 
ATOM   3589  N  N     . GLY B 1 248 ? 203.185 219.365 200.179 1.00 6.91   ? 248 GLY B N     1 
ATOM   3590  C  CA    . GLY B 1 248 ? 204.465 218.772 199.844 1.00 7.35   ? 248 GLY B CA    1 
ATOM   3591  C  C     . GLY B 1 248 ? 204.460 217.991 198.542 1.00 7.76   ? 248 GLY B C     1 
ATOM   3592  O  O     . GLY B 1 248 ? 205.251 217.073 198.410 1.00 8.39   ? 248 GLY B O     1 
ATOM   3593  N  N     . GLU B 1 249 ? 203.609 218.368 197.588 1.00 8.48   ? 249 GLU B N     1 
ATOM   3594  C  CA    . GLU B 1 249 ? 203.415 217.585 196.372 1.00 10.08  ? 249 GLU B CA    1 
ATOM   3595  C  C     . GLU B 1 249 ? 203.529 218.505 195.161 1.00 9.23   ? 249 GLU B C     1 
ATOM   3596  O  O     . GLU B 1 249 ? 203.198 219.675 195.228 1.00 9.56   ? 249 GLU B O     1 
ATOM   3597  C  CB    . GLU B 1 249 ? 202.058 216.860 196.434 1.00 11.77  ? 249 GLU B CB    1 
ATOM   3598  C  CG    . GLU B 1 249 ? 201.436 216.449 195.103 1.00 14.03  ? 249 GLU B CG    1 
ATOM   3599  C  CD    . GLU B 1 249 ? 202.154 215.291 194.416 1.00 16.11  ? 249 GLU B CD    1 
ATOM   3600  O  OE1   . GLU B 1 249 ? 201.554 214.757 193.443 1.00 15.95  ? 249 GLU B OE1   1 
ATOM   3601  O  OE2   . GLU B 1 249 ? 203.306 214.927 194.790 1.00 17.34  ? 249 GLU B OE2   1 
ATOM   3602  N  N     . VAL B 1 250 ? 203.961 217.922 194.047 1.00 9.44   ? 250 VAL B N     1 
ATOM   3603  C  CA    . VAL B 1 250 ? 204.003 218.590 192.765 1.00 9.96   ? 250 VAL B CA    1 
ATOM   3604  C  C     . VAL B 1 250 ? 202.880 218.034 191.900 1.00 9.96   ? 250 VAL B C     1 
ATOM   3605  O  O     . VAL B 1 250 ? 202.786 216.822 191.720 1.00 11.26  ? 250 VAL B O     1 
ATOM   3606  C  CB    . VAL B 1 250 ? 205.361 218.377 192.074 1.00 10.45  ? 250 VAL B CB    1 
ATOM   3607  C  CG1   . VAL B 1 250 ? 205.401 219.095 190.737 1.00 10.84  ? 250 VAL B CG1   1 
ATOM   3608  C  CG2   . VAL B 1 250 ? 206.505 218.858 192.945 1.00 10.84  ? 250 VAL B CG2   1 
ATOM   3609  N  N     . ILE B 1 251 ? 202.039 218.923 191.374 1.00 9.57   ? 251 ILE B N     1 
ATOM   3610  C  CA    . ILE B 1 251 ? 200.958 218.530 190.490 1.00 9.59   ? 251 ILE B CA    1 
ATOM   3611  C  C     . ILE B 1 251 ? 201.283 218.986 189.076 1.00 9.61   ? 251 ILE B C     1 
ATOM   3612  O  O     . ILE B 1 251 ? 201.404 220.179 188.826 1.00 9.65   ? 251 ILE B O     1 
ATOM   3613  C  CB    . ILE B 1 251 ? 199.617 219.121 190.963 1.00 9.50   ? 251 ILE B CB    1 
ATOM   3614  C  CG1   . ILE B 1 251 ? 199.253 218.589 192.338 1.00 9.95   ? 251 ILE B CG1   1 
ATOM   3615  C  CG2   . ILE B 1 251 ? 198.512 218.829 189.955 1.00 9.21   ? 251 ILE B CG2   1 
ATOM   3616  C  CD1   . ILE B 1 251 ? 198.089 219.297 192.983 1.00 10.38  ? 251 ILE B CD1   1 
ATOM   3617  N  N     . ARG B 1 252 ? 201.397 218.033 188.160 1.00 10.26  ? 252 ARG B N     1 
ATOM   3618  C  CA    . ARG B 1 252 ? 201.571 218.335 186.753 1.00 11.60  ? 252 ARG B CA    1 
ATOM   3619  C  C     . ARG B 1 252 ? 200.234 218.761 186.150 1.00 10.66  ? 252 ARG B C     1 
ATOM   3620  O  O     . ARG B 1 252 ? 199.249 218.032 186.237 1.00 11.20  ? 252 ARG B O     1 
ATOM   3621  C  CB    . ARG B 1 252 ? 202.128 217.139 185.991 1.00 13.54  ? 252 ARG B CB    1 
ATOM   3622  C  CG    . ARG B 1 252 ? 203.528 216.718 186.418 1.00 16.01  ? 252 ARG B CG    1 
ATOM   3623  C  CD    . ARG B 1 252 ? 203.975 215.489 185.678 1.00 18.32  ? 252 ARG B CD    1 
ATOM   3624  N  NE    . ARG B 1 252 ? 204.048 215.739 184.232 1.00 21.12  ? 252 ARG B NE    1 
ATOM   3625  C  CZ    . ARG B 1 252 ? 205.075 215.420 183.441 1.00 23.58  ? 252 ARG B CZ    1 
ATOM   3626  N  NH1   . ARG B 1 252 ? 206.135 214.796 183.923 1.00 24.73  ? 252 ARG B NH1   1 
ATOM   3627  N  NH2   . ARG B 1 252 ? 204.999 215.700 182.153 1.00 24.21  ? 252 ARG B NH2   1 
ATOM   3628  N  N     . LEU B 1 253 ? 200.219 219.945 185.547 1.00 9.87   ? 253 LEU B N     1 
ATOM   3629  C  CA    . LEU B 1 253 ? 199.048 220.456 184.858 1.00 9.93   ? 253 LEU B CA    1 
ATOM   3630  C  C     . LEU B 1 253 ? 199.431 220.650 183.396 1.00 10.43  ? 253 LEU B C     1 
ATOM   3631  O  O     . LEU B 1 253 ? 199.859 221.735 183.000 1.00 9.80   ? 253 LEU B O     1 
ATOM   3632  C  CB    . LEU B 1 253 ? 198.610 221.765 185.515 1.00 10.18  ? 253 LEU B CB    1 
ATOM   3633  C  CG    . LEU B 1 253 ? 197.347 222.444 184.988 1.00 10.52  ? 253 LEU B CG    1 
ATOM   3634  C  CD1   . LEU B 1 253 ? 196.118 221.601 185.189 1.00 10.22  ? 253 LEU B CD1   1 
ATOM   3635  C  CD2   . LEU B 1 253 ? 197.166 223.775 185.682 1.00 10.96  ? 253 LEU B CD2   1 
ATOM   3636  N  N     . ASP B 1 254 ? 199.297 219.577 182.605 1.00 11.14  ? 254 ASP B N     1 
ATOM   3637  C  CA    . ASP B 1 254 ? 199.924 219.562 181.292 1.00 11.89  ? 254 ASP B CA    1 
ATOM   3638  C  C     . ASP B 1 254 ? 199.108 218.854 180.215 1.00 12.27  ? 254 ASP B C     1 
ATOM   3639  O  O     . ASP B 1 254 ? 199.608 218.686 179.099 1.00 13.28  ? 254 ASP B O     1 
ATOM   3640  C  CB    . ASP B 1 254 ? 201.297 218.918 181.392 1.00 12.81  ? 254 ASP B CB    1 
ATOM   3641  C  CG    . ASP B 1 254 ? 201.303 217.543 182.032 1.00 13.94  ? 254 ASP B CG    1 
ATOM   3642  O  OD1   . ASP B 1 254 ? 200.233 216.913 182.081 1.00 14.41  ? 254 ASP B OD1   1 
ATOM   3643  O  OD2   . ASP B 1 254 ? 202.373 217.150 182.538 1.00 15.72  ? 254 ASP B OD2   1 
ATOM   3644  N  N     . GLY B 1 255 ? 197.872 218.437 180.510 1.00 12.21  ? 255 GLY B N     1 
ATOM   3645  C  CA    . GLY B 1 255 ? 197.076 217.696 179.539 1.00 12.57  ? 255 GLY B CA    1 
ATOM   3646  C  C     . GLY B 1 255 ? 197.728 216.384 179.106 1.00 12.39  ? 255 GLY B C     1 
ATOM   3647  O  O     . GLY B 1 255 ? 197.520 215.938 177.984 1.00 14.03  ? 255 GLY B O     1 
ATOM   3648  N  N     . ALA B 1 256 ? 198.529 215.771 179.990 1.00 13.02  ? 256 ALA B N     1 
ATOM   3649  C  CA    . ALA B 1 256 ? 199.158 214.477 179.769 1.00 13.16  ? 256 ALA B CA    1 
ATOM   3650  C  C     . ALA B 1 256 ? 200.284 214.527 178.741 1.00 14.96  ? 256 ALA B C     1 
ATOM   3651  O  O     . ALA B 1 256 ? 200.625 213.497 178.167 1.00 16.00  ? 256 ALA B O     1 
ATOM   3652  C  CB    . ALA B 1 256 ? 198.131 213.424 179.396 1.00 12.79  ? 256 ALA B CB    1 
ATOM   3653  N  N     . ILE B 1 257 ? 200.889 215.691 178.518 1.00 16.63  ? 257 ILE B N     1 
ATOM   3654  C  CA    . ILE B 1 257 ? 201.994 215.776 177.569 1.00 17.62  ? 257 ILE B CA    1 
ATOM   3655  C  C     . ILE B 1 257 ? 203.286 215.284 178.221 1.00 19.40  ? 257 ILE B C     1 
ATOM   3656  O  O     . ILE B 1 257 ? 203.493 215.448 179.424 1.00 20.74  ? 257 ILE B O     1 
ATOM   3657  C  CB    . ILE B 1 257 ? 202.156 217.200 177.021 1.00 18.26  ? 257 ILE B CB    1 
ATOM   3658  C  CG1   . ILE B 1 257 ? 202.993 217.191 175.743 1.00 19.65  ? 257 ILE B CG1   1 
ATOM   3659  C  CG2   . ILE B 1 257 ? 202.737 218.132 178.090 1.00 18.69  ? 257 ILE B CG2   1 
ATOM   3660  C  CD1   . ILE B 1 257 ? 202.992 218.514 174.994 1.00 20.63  ? 257 ILE B CD1   1 
ATOM   3661  N  N     . ARG B 1 258 ? 204.144 214.670 177.401 1.00 19.97  ? 258 ARG B N     1 
ATOM   3662  C  CA    . ARG B 1 258 ? 205.508 214.350 177.787 1.00 21.56  ? 258 ARG B CA    1 
ATOM   3663  C  C     . ARG B 1 258 ? 206.435 214.896 176.705 1.00 23.35  ? 258 ARG B C     1 
ATOM   3664  O  O     . ARG B 1 258 ? 206.380 214.448 175.564 1.00 22.70  ? 258 ARG B O     1 
ATOM   3665  C  CB    . ARG B 1 258 ? 205.715 212.845 177.986 1.00 22.02  ? 258 ARG B CB    1 
ATOM   3666  C  CG    . ARG B 1 258 ? 204.820 212.231 179.059 1.00 23.04  ? 258 ARG B CG    1 
ATOM   3667  C  CD    . ARG B 1 258 ? 205.172 212.767 180.425 1.00 22.65  ? 258 ARG B CD    1 
ATOM   3668  N  NE    . ARG B 1 258 ? 204.388 212.123 181.483 1.00 22.58  ? 258 ARG B NE    1 
ATOM   3669  C  CZ    . ARG B 1 258 ? 203.237 212.568 181.964 1.00 21.98  ? 258 ARG B CZ    1 
ATOM   3670  N  NH1   . ARG B 1 258 ? 202.645 213.639 181.447 1.00 20.84  ? 258 ARG B NH1   1 
ATOM   3671  N  NH2   . ARG B 1 258 ? 202.670 211.927 182.975 1.00 22.02  ? 258 ARG B NH2   1 
ATOM   3672  N  N     . MET B 1 259 ? 207.275 215.865 177.069 1.00 25.07  ? 259 MET B N     1 
ATOM   3673  C  CA    . MET B 1 259 ? 208.006 216.650 176.088 1.00 29.28  ? 259 MET B CA    1 
ATOM   3674  C  C     . MET B 1 259 ? 209.046 215.804 175.357 1.00 29.99  ? 259 MET B C     1 
ATOM   3675  O  O     . MET B 1 259 ? 209.782 215.037 175.966 1.00 31.09  ? 259 MET B O     1 
ATOM   3676  C  CB    . MET B 1 259 ? 208.686 217.845 176.759 1.00 31.11  ? 259 MET B CB    1 
ATOM   3677  C  CG    . MET B 1 259 ? 207.721 218.743 177.515 1.00 32.97  ? 259 MET B CG    1 
ATOM   3678  S  SD    . MET B 1 259 ? 206.407 219.439 176.494 1.00 37.98  ? 259 MET B SD    1 
ATOM   3679  C  CE    . MET B 1 259 ? 207.263 220.764 175.627 1.00 38.56  ? 259 MET B CE    1 
ATOM   3680  N  N     . GLN B 1 260 ? 209.103 215.963 174.041 1.00 33.60  ? 260 GLN B N     1 
ATOM   3681  C  CA    . GLN B 1 260 ? 210.141 215.350 173.222 1.00 36.35  ? 260 GLN B CA    1 
ATOM   3682  C  C     . GLN B 1 260 ? 211.441 216.141 173.389 1.00 34.31  ? 260 GLN B C     1 
ATOM   3683  O  O     . GLN B 1 260 ? 211.440 217.273 173.891 1.00 35.80  ? 260 GLN B O     1 
ATOM   3684  C  CB    . GLN B 1 260 ? 209.737 215.383 171.748 1.00 42.93  ? 260 GLN B CB    1 
ATOM   3685  C  CG    . GLN B 1 260 ? 208.402 214.738 171.374 1.00 48.93  ? 260 GLN B CG    1 
ATOM   3686  C  CD    . GLN B 1 260 ? 207.863 215.246 170.038 1.00 48.24  ? 260 GLN B CD    1 
ATOM   3687  O  OE1   . GLN B 1 260 ? 208.284 216.286 169.521 1.00 40.58  ? 260 GLN B OE1   1 
ATOM   3688  N  NE2   . GLN B 1 260 ? 206.948 214.499 169.440 1.00 45.37  ? 260 GLN B NE2   1 
ATOM   3689  N  N     . PRO B 1 261 ? 212.606 215.577 173.003 1.00 37.93  ? 261 PRO B N     1 
ATOM   3690  C  CA    . PRO B 1 261 ? 213.847 216.355 172.957 1.00 41.82  ? 261 PRO B CA    1 
ATOM   3691  C  C     . PRO B 1 261 ? 213.739 217.654 172.158 1.00 48.19  ? 261 PRO B C     1 
ATOM   3692  O  O     . PRO B 1 261 ? 213.098 217.632 171.077 1.00 52.63  ? 261 PRO B O     1 
ATOM   3693  C  CB    . PRO B 1 261 ? 214.855 215.384 172.314 1.00 39.78  ? 261 PRO B CB    1 
ATOM   3694  C  CG    . PRO B 1 261 ? 214.306 214.024 172.640 1.00 38.76  ? 261 PRO B CG    1 
ATOM   3695  C  CD    . PRO B 1 261 ? 212.799 214.171 172.608 1.00 37.97  ? 261 PRO B CD    1 
ATOM   3696  O  OXT   . PRO B 1 261 ? 214.315 218.654 172.632 1.00 47.04  ? 261 PRO B OXT   1 
ATOM   3697  N  N     . SER C 1 7   ? 181.678 222.834 185.970 1.00 33.79  ? 7   SER C N     1 
ATOM   3698  C  CA    . SER C 1 7   ? 180.700 222.465 187.029 1.00 32.95  ? 7   SER C CA    1 
ATOM   3699  C  C     . SER C 1 7   ? 180.304 220.998 186.896 1.00 29.48  ? 7   SER C C     1 
ATOM   3700  O  O     . SER C 1 7   ? 180.176 220.491 185.785 1.00 30.20  ? 7   SER C O     1 
ATOM   3701  C  CB    . SER C 1 7   ? 179.488 223.359 186.974 1.00 32.94  ? 7   SER C CB    1 
ATOM   3702  O  OG    . SER C 1 7   ? 178.587 223.041 188.021 1.00 34.97  ? 7   SER C OG    1 
ATOM   3703  N  N     . VAL C 1 8   ? 180.063 220.335 188.033 1.00 26.84  ? 8   VAL C N     1 
ATOM   3704  C  CA    . VAL C 1 8   ? 179.671 218.933 188.025 1.00 25.55  ? 8   VAL C CA    1 
ATOM   3705  C  C     . VAL C 1 8   ? 178.152 218.779 188.000 1.00 24.65  ? 8   VAL C C     1 
ATOM   3706  O  O     . VAL C 1 8   ? 177.654 217.659 187.997 1.00 23.87  ? 8   VAL C O     1 
ATOM   3707  C  CB    . VAL C 1 8   ? 180.246 218.171 189.227 1.00 24.90  ? 8   VAL C CB    1 
ATOM   3708  C  CG1   . VAL C 1 8   ? 181.753 218.355 189.330 1.00 24.97  ? 8   VAL C CG1   1 
ATOM   3709  C  CG2   . VAL C 1 8   ? 179.561 218.564 190.521 1.00 24.77  ? 8   VAL C CG2   1 
ATOM   3710  N  N     . LYS C 1 9   ? 177.413 219.888 187.983 1.00 26.73  ? 9   LYS C N     1 
ATOM   3711  C  CA    . LYS C 1 9   ? 175.962 219.825 187.939 1.00 27.72  ? 9   LYS C CA    1 
ATOM   3712  C  C     . LYS C 1 9   ? 175.501 219.154 186.648 1.00 25.79  ? 9   LYS C C     1 
ATOM   3713  O  O     . LYS C 1 9   ? 175.941 219.510 185.557 1.00 27.15  ? 9   LYS C O     1 
ATOM   3714  C  CB    . LYS C 1 9   ? 175.363 221.225 188.054 1.00 32.34  ? 9   LYS C CB    1 
ATOM   3715  C  CG    . LYS C 1 9   ? 173.867 221.240 188.250 1.00 37.61  ? 9   LYS C CG    1 
ATOM   3716  C  CD    . LYS C 1 9   ? 173.327 222.657 188.414 1.00 43.44  ? 9   LYS C CD    1 
ATOM   3717  C  CE    . LYS C 1 9   ? 171.968 222.832 187.802 1.00 46.99  ? 9   LYS C CE    1 
ATOM   3718  N  NZ    . LYS C 1 9   ? 172.063 222.713 186.342 1.00 49.81  ? 9   LYS C NZ    1 
ATOM   3719  N  N     . GLY C 1 10  ? 174.630 218.150 186.795 1.00 24.35  ? 10  GLY C N     1 
ATOM   3720  C  CA    . GLY C 1 10  ? 174.095 217.421 185.661 1.00 23.97  ? 10  GLY C CA    1 
ATOM   3721  C  C     . GLY C 1 10  ? 174.968 216.248 185.220 1.00 22.92  ? 10  GLY C C     1 
ATOM   3722  O  O     . GLY C 1 10  ? 174.522 215.445 184.406 1.00 24.05  ? 10  GLY C O     1 
ATOM   3723  N  N     . LEU C 1 11  ? 176.201 216.141 185.729 1.00 20.31  ? 11  LEU C N     1 
ATOM   3724  C  CA    . LEU C 1 11  ? 177.067 215.029 185.363 1.00 19.14  ? 11  LEU C CA    1 
ATOM   3725  C  C     . LEU C 1 11  ? 176.607 213.754 186.065 1.00 17.62  ? 11  LEU C C     1 
ATOM   3726  O  O     . LEU C 1 11  ? 176.063 213.792 187.161 1.00 18.09  ? 11  LEU C O     1 
ATOM   3727  C  CB    . LEU C 1 11  ? 178.524 215.332 185.713 1.00 19.76  ? 11  LEU C CB    1 
ATOM   3728  C  CG    . LEU C 1 11  ? 179.173 216.496 184.955 1.00 20.08  ? 11  LEU C CG    1 
ATOM   3729  C  CD1   . LEU C 1 11  ? 180.649 216.569 185.305 1.00 20.34  ? 11  LEU C CD1   1 
ATOM   3730  C  CD2   . LEU C 1 11  ? 179.006 216.380 183.459 1.00 20.23  ? 11  LEU C CD2   1 
ATOM   3731  N  N     . VAL C 1 12  ? 176.842 212.619 185.407 1.00 16.26  ? 12  VAL C N     1 
ATOM   3732  C  CA    . VAL C 1 12  ? 176.556 211.314 185.968 1.00 15.93  ? 12  VAL C CA    1 
ATOM   3733  C  C     . VAL C 1 12  ? 177.883 210.635 186.277 1.00 14.91  ? 12  VAL C C     1 
ATOM   3734  O  O     . VAL C 1 12  ? 178.710 210.461 185.380 1.00 15.43  ? 12  VAL C O     1 
ATOM   3735  C  CB    . VAL C 1 12  ? 175.707 210.456 185.018 1.00 16.18  ? 12  VAL C CB    1 
ATOM   3736  C  CG1   . VAL C 1 12  ? 175.415 209.084 185.618 1.00 16.19  ? 12  VAL C CG1   1 
ATOM   3737  C  CG2   . VAL C 1 12  ? 174.412 211.171 184.661 1.00 16.47  ? 12  VAL C CG2   1 
ATOM   3738  N  N     . ALA C 1 13  ? 178.049 210.249 187.547 1.00 14.74  ? 13  ALA C N     1 
ATOM   3739  C  CA    . ALA C 1 13  ? 179.274 209.621 188.010 1.00 14.85  ? 13  ALA C CA    1 
ATOM   3740  C  C     . ALA C 1 13  ? 178.990 208.182 188.413 1.00 14.35  ? 13  ALA C C     1 
ATOM   3741  O  O     . ALA C 1 13  ? 178.061 207.917 189.167 1.00 15.30  ? 13  ALA C O     1 
ATOM   3742  C  CB    . ALA C 1 13  ? 179.869 210.395 189.164 1.00 14.62  ? 13  ALA C CB    1 
ATOM   3743  N  N     . VAL C 1 14  ? 179.818 207.266 187.912 1.00 13.84  ? 14  VAL C N     1 
ATOM   3744  C  CA    . VAL C 1 14  ? 179.836 205.902 188.399 1.00 13.52  ? 14  VAL C CA    1 
ATOM   3745  C  C     . VAL C 1 14  ? 180.980 205.784 189.393 1.00 12.88  ? 14  VAL C C     1 
ATOM   3746  O  O     . VAL C 1 14  ? 182.135 205.919 189.023 1.00 12.95  ? 14  VAL C O     1 
ATOM   3747  C  CB    . VAL C 1 14  ? 179.976 204.893 187.252 1.00 14.27  ? 14  VAL C CB    1 
ATOM   3748  C  CG1   . VAL C 1 14  ? 180.179 203.489 187.784 1.00 14.62  ? 14  VAL C CG1   1 
ATOM   3749  C  CG2   . VAL C 1 14  ? 178.763 204.956 186.337 1.00 14.89  ? 14  VAL C CG2   1 
ATOM   3750  N  N     . ILE C 1 15  ? 180.638 205.536 190.655 1.00 12.59  ? 15  ILE C N     1 
ATOM   3751  C  CA    . ILE C 1 15  ? 181.614 205.548 191.724 1.00 12.68  ? 15  ILE C CA    1 
ATOM   3752  C  C     . ILE C 1 15  ? 181.768 204.133 192.257 1.00 13.03  ? 15  ILE C C     1 
ATOM   3753  O  O     . ILE C 1 15  ? 180.895 203.594 192.914 1.00 12.89  ? 15  ILE C O     1 
ATOM   3754  C  CB    . ILE C 1 15  ? 181.228 206.540 192.827 1.00 12.99  ? 15  ILE C CB    1 
ATOM   3755  C  CG1   . ILE C 1 15  ? 181.097 207.941 192.251 1.00 13.03  ? 15  ILE C CG1   1 
ATOM   3756  C  CG2   . ILE C 1 15  ? 182.242 206.468 193.966 1.00 12.68  ? 15  ILE C CG2   1 
ATOM   3757  C  CD1   . ILE C 1 15  ? 180.386 208.907 193.150 1.00 14.25  ? 15  ILE C CD1   1 
ATOM   3758  N  N     . THR C 1 16  ? 182.913 203.539 191.946 1.00 14.11  ? 16  THR C N     1 
ATOM   3759  C  CA    . THR C 1 16  ? 183.207 202.186 192.364 1.00 15.35  ? 16  THR C CA    1 
ATOM   3760  C  C     . THR C 1 16  ? 183.581 202.173 193.841 1.00 15.59  ? 16  THR C C     1 
ATOM   3761  O  O     . THR C 1 16  ? 184.286 203.052 194.323 1.00 15.72  ? 16  THR C O     1 
ATOM   3762  C  CB    . THR C 1 16  ? 184.344 201.687 191.486 1.00 18.60  ? 16  THR C CB    1 
ATOM   3763  O  OG1   . THR C 1 16  ? 183.920 201.577 190.129 1.00 17.27  ? 16  THR C OG1   1 
ATOM   3764  C  CG2   . THR C 1 16  ? 184.666 200.291 191.871 1.00 22.28  ? 16  THR C CG2   1 
ATOM   3765  N  N     . GLY C 1 17  ? 183.116 201.164 194.566 1.00 15.82  ? 17  GLY C N     1 
ATOM   3766  C  CA    . GLY C 1 17  ? 183.299 201.129 196.005 1.00 15.36  ? 17  GLY C CA    1 
ATOM   3767  C  C     . GLY C 1 17  ? 182.576 202.301 196.687 1.00 16.52  ? 17  GLY C C     1 
ATOM   3768  O  O     . GLY C 1 17  ? 183.045 202.804 197.698 1.00 16.11  ? 17  GLY C O     1 
ATOM   3769  N  N     . GLY C 1 18  ? 181.418 202.713 196.147 1.00 16.52  ? 18  GLY C N     1 
ATOM   3770  C  CA    . GLY C 1 18  ? 180.740 203.923 196.580 1.00 17.68  ? 18  GLY C CA    1 
ATOM   3771  C  C     . GLY C 1 18  ? 179.883 203.761 197.835 1.00 18.21  ? 18  GLY C C     1 
ATOM   3772  O  O     . GLY C 1 18  ? 179.265 204.730 198.260 1.00 19.82  ? 18  GLY C O     1 
ATOM   3773  N  N     . ALA C 1 19  ? 179.848 202.565 198.433 1.00 18.86  ? 19  ALA C N     1 
ATOM   3774  C  CA    . ALA C 1 19  ? 179.025 202.337 199.612 1.00 19.59  ? 19  ALA C CA    1 
ATOM   3775  C  C     . ALA C 1 19  ? 179.721 202.761 200.905 1.00 19.76  ? 19  ALA C C     1 
ATOM   3776  O  O     . ALA C 1 19  ? 179.079 202.786 201.947 1.00 20.44  ? 19  ALA C O     1 
ATOM   3777  C  CB    . ALA C 1 19  ? 178.607 200.885 199.694 1.00 19.59  ? 19  ALA C CB    1 
ATOM   3778  N  N     . SER C 1 20  ? 181.025 203.053 200.865 1.00 19.70  ? 20  SER C N     1 
ATOM   3779  C  CA    . SER C 1 20  ? 181.749 203.406 202.072 1.00 19.44  ? 20  SER C CA    1 
ATOM   3780  C  C     . SER C 1 20  ? 183.018 204.175 201.727 1.00 17.70  ? 20  SER C C     1 
ATOM   3781  O  O     . SER C 1 20  ? 183.438 204.196 200.578 1.00 16.61  ? 20  SER C O     1 
ATOM   3782  C  CB    . SER C 1 20  ? 182.078 202.174 202.886 1.00 20.62  ? 20  SER C CB    1 
ATOM   3783  O  OG    . SER C 1 20  ? 183.134 201.423 202.298 1.00 23.03  ? 20  SER C OG    1 
ATOM   3784  N  N     . GLY C 1 21  ? 183.625 204.772 202.752 1.00 15.89  ? 21  GLY C N     1 
ATOM   3785  C  CA    . GLY C 1 21  ? 184.955 205.351 202.647 1.00 14.86  ? 21  GLY C CA    1 
ATOM   3786  C  C     . GLY C 1 21  ? 185.038 206.451 201.594 1.00 14.13  ? 21  GLY C C     1 
ATOM   3787  O  O     . GLY C 1 21  ? 184.175 207.312 201.525 1.00 13.87  ? 21  GLY C O     1 
ATOM   3788  N  N     . LEU C 1 22  ? 186.106 206.424 200.788 1.00 13.33  ? 22  LEU C N     1 
ATOM   3789  C  CA    . LEU C 1 22  ? 186.366 207.485 199.835 1.00 13.04  ? 22  LEU C CA    1 
ATOM   3790  C  C     . LEU C 1 22  ? 185.277 207.530 198.767 1.00 12.32  ? 22  LEU C C     1 
ATOM   3791  O  O     . LEU C 1 22  ? 184.875 208.611 198.354 1.00 12.42  ? 22  LEU C O     1 
ATOM   3792  C  CB    . LEU C 1 22  ? 187.744 207.284 199.207 1.00 12.72  ? 22  LEU C CB    1 
ATOM   3793  C  CG    . LEU C 1 22  ? 188.922 207.269 200.188 1.00 13.28  ? 22  LEU C CG    1 
ATOM   3794  C  CD1   . LEU C 1 22  ? 190.196 207.138 199.386 1.00 13.25  ? 22  LEU C CD1   1 
ATOM   3795  C  CD2   . LEU C 1 22  ? 188.944 208.516 201.058 1.00 13.71  ? 22  LEU C CD2   1 
ATOM   3796  N  N     . GLY C 1 23  ? 184.813 206.367 198.310 1.00 11.74  ? 23  GLY C N     1 
ATOM   3797  C  CA    . GLY C 1 23  ? 183.773 206.321 197.301 1.00 11.84  ? 23  GLY C CA    1 
ATOM   3798  C  C     . GLY C 1 23  ? 182.474 206.974 197.777 1.00 12.04  ? 23  GLY C C     1 
ATOM   3799  O  O     . GLY C 1 23  ? 181.843 207.729 197.044 1.00 11.15  ? 23  GLY C O     1 
ATOM   3800  N  N     . LEU C 1 24  ? 182.074 206.689 199.012 1.00 12.65  ? 24  LEU C N     1 
ATOM   3801  C  CA    . LEU C 1 24  ? 180.850 207.254 199.557 1.00 12.80  ? 24  LEU C CA    1 
ATOM   3802  C  C     . LEU C 1 24  ? 180.981 208.765 199.716 1.00 12.16  ? 24  LEU C C     1 
ATOM   3803  O  O     . LEU C 1 24  ? 180.058 209.496 199.382 1.00 11.94  ? 24  LEU C O     1 
ATOM   3804  C  CB    . LEU C 1 24  ? 180.514 206.593 200.891 1.00 14.19  ? 24  LEU C CB    1 
ATOM   3805  C  CG    . LEU C 1 24  ? 179.275 207.133 201.609 1.00 15.72  ? 24  LEU C CG    1 
ATOM   3806  C  CD1   . LEU C 1 24  ? 178.063 207.003 200.735 1.00 15.76  ? 24  LEU C CD1   1 
ATOM   3807  C  CD2   . LEU C 1 24  ? 179.078 206.417 202.931 1.00 17.32  ? 24  LEU C CD2   1 
ATOM   3808  N  N     . ALA C 1 25  ? 182.124 209.238 200.228 1.00 11.77  ? 25  ALA C N     1 
ATOM   3809  C  CA    . ALA C 1 25  ? 182.342 210.669 200.384 1.00 11.44  ? 25  ALA C CA    1 
ATOM   3810  C  C     . ALA C 1 25  ? 182.276 211.370 199.030 1.00 10.88  ? 25  ALA C C     1 
ATOM   3811  O  O     . ALA C 1 25  ? 181.745 212.466 198.922 1.00 11.47  ? 25  ALA C O     1 
ATOM   3812  C  CB    . ALA C 1 25  ? 183.651 210.940 201.089 1.00 11.83  ? 25  ALA C CB    1 
ATOM   3813  N  N     . THR C 1 26  ? 182.847 210.748 197.997 1.00 10.53  ? 26  THR C N     1 
ATOM   3814  C  CA    . THR C 1 26  ? 182.799 211.298 196.655 1.00 10.52  ? 26  THR C CA    1 
ATOM   3815  C  C     . THR C 1 26  ? 181.346 211.395 196.187 1.00 11.05  ? 26  THR C C     1 
ATOM   3816  O  O     . THR C 1 26  ? 180.961 212.383 195.575 1.00 10.55  ? 26  THR C O     1 
ATOM   3817  C  CB    . THR C 1 26  ? 183.627 210.447 195.691 1.00 10.18  ? 26  THR C CB    1 
ATOM   3818  O  OG1   . THR C 1 26  ? 184.964 210.413 196.180 1.00 9.89   ? 26  THR C OG1   1 
ATOM   3819  C  CG2   . THR C 1 26  ? 183.596 211.004 194.279 1.00 10.02  ? 26  THR C CG2   1 
ATOM   3820  N  N     . ALA C 1 27  ? 180.550 210.354 196.455 1.00 12.22  ? 27  ALA C N     1 
ATOM   3821  C  CA    . ALA C 1 27  ? 179.146 210.354 196.071 1.00 13.51  ? 27  ALA C CA    1 
ATOM   3822  C  C     . ALA C 1 27  ? 178.378 211.461 196.785 1.00 13.90  ? 27  ALA C C     1 
ATOM   3823  O  O     . ALA C 1 27  ? 177.599 212.165 196.154 1.00 14.92  ? 27  ALA C O     1 
ATOM   3824  C  CB    . ALA C 1 27  ? 178.527 209.001 196.355 1.00 13.83  ? 27  ALA C CB    1 
ATOM   3825  N  N     . GLU C 1 28  ? 178.603 211.619 198.089 1.00 15.56  ? 28  GLU C N     1 
ATOM   3826  C  CA    . GLU C 1 28  ? 177.890 212.621 198.865 1.00 17.42  ? 28  GLU C CA    1 
ATOM   3827  C  C     . GLU C 1 28  ? 178.187 214.021 198.338 1.00 16.09  ? 28  GLU C C     1 
ATOM   3828  O  O     . GLU C 1 28  ? 177.279 214.837 198.216 1.00 15.89  ? 28  GLU C O     1 
ATOM   3829  C  CB    . GLU C 1 28  ? 178.258 212.528 200.346 1.00 20.29  ? 28  GLU C CB    1 
ATOM   3830  C  CG    . GLU C 1 28  ? 177.920 211.170 200.951 1.00 24.77  ? 28  GLU C CG    1 
ATOM   3831  C  CD    . GLU C 1 28  ? 178.390 211.019 202.390 1.00 29.82  ? 28  GLU C CD    1 
ATOM   3832  O  OE1   . GLU C 1 28  ? 177.852 210.139 203.105 1.00 32.42  ? 28  GLU C OE1   1 
ATOM   3833  O  OE2   . GLU C 1 28  ? 179.305 211.766 202.804 1.00 34.82  ? 28  GLU C OE2   1 
ATOM   3834  N  N     . ARG C 1 29  ? 179.456 214.301 198.024 1.00 14.48  ? 29  ARG C N     1 
ATOM   3835  C  CA    . ARG C 1 29  ? 179.823 215.622 197.547 1.00 14.55  ? 29  ARG C CA    1 
ATOM   3836  C  C     . ARG C 1 29  ? 179.221 215.887 196.170 1.00 14.34  ? 29  ARG C C     1 
ATOM   3837  O  O     . ARG C 1 29  ? 178.614 216.935 195.949 1.00 15.74  ? 29  ARG C O     1 
ATOM   3838  C  CB    . ARG C 1 29  ? 181.345 215.793 197.510 1.00 14.52  ? 29  ARG C CB    1 
ATOM   3839  C  CG    . ARG C 1 29  ? 181.725 217.188 197.044 1.00 15.50  ? 29  ARG C CG    1 
ATOM   3840  C  CD    . ARG C 1 29  ? 183.214 217.419 197.121 1.00 17.14  ? 29  ARG C CD    1 
ATOM   3841  N  NE    . ARG C 1 29  ? 183.509 218.811 196.770 1.00 18.72  ? 29  ARG C NE    1 
ATOM   3842  C  CZ    . ARG C 1 29  ? 183.592 219.809 197.647 1.00 20.07  ? 29  ARG C CZ    1 
ATOM   3843  N  NH1   . ARG C 1 29  ? 183.483 219.597 198.945 1.00 20.52  ? 29  ARG C NH1   1 
ATOM   3844  N  NH2   . ARG C 1 29  ? 183.830 221.028 197.210 1.00 22.43  ? 29  ARG C NH2   1 
ATOM   3845  N  N     . LEU C 1 30  ? 179.396 214.949 195.241 1.00 14.28  ? 30  LEU C N     1 
ATOM   3846  C  CA    . LEU C 1 30  ? 178.934 215.154 193.876 1.00 14.83  ? 30  LEU C CA    1 
ATOM   3847  C  C     . LEU C 1 30  ? 177.414 215.292 193.834 1.00 15.38  ? 30  LEU C C     1 
ATOM   3848  O  O     . LEU C 1 30  ? 176.891 216.138 193.118 1.00 15.79  ? 30  LEU C O     1 
ATOM   3849  C  CB    . LEU C 1 30  ? 179.420 214.031 192.965 1.00 15.27  ? 30  LEU C CB    1 
ATOM   3850  C  CG    . LEU C 1 30  ? 180.935 213.955 192.747 1.00 15.92  ? 30  LEU C CG    1 
ATOM   3851  C  CD1   . LEU C 1 30  ? 181.289 212.885 191.730 1.00 15.86  ? 30  LEU C CD1   1 
ATOM   3852  C  CD2   . LEU C 1 30  ? 181.515 215.299 192.324 1.00 16.15  ? 30  LEU C CD2   1 
ATOM   3853  N  N     . VAL C 1 31  ? 176.700 214.453 194.579 1.00 16.43  ? 31  VAL C N     1 
ATOM   3854  C  CA    . VAL C 1 31  ? 175.249 214.550 194.623 1.00 17.80  ? 31  VAL C CA    1 
ATOM   3855  C  C     . VAL C 1 31  ? 174.826 215.883 195.235 1.00 18.66  ? 31  VAL C C     1 
ATOM   3856  O  O     . VAL C 1 31  ? 173.913 216.538 194.741 1.00 20.22  ? 31  VAL C O     1 
ATOM   3857  C  CB    . VAL C 1 31  ? 174.627 213.356 195.367 1.00 18.84  ? 31  VAL C CB    1 
ATOM   3858  C  CG1   . VAL C 1 31  ? 173.152 213.593 195.650 1.00 19.17  ? 31  VAL C CG1   1 
ATOM   3859  C  CG2   . VAL C 1 31  ? 174.792 212.072 194.567 1.00 18.75  ? 31  VAL C CG2   1 
ATOM   3860  N  N     . GLY C 1 32  ? 175.506 216.301 196.303 1.00 19.80  ? 32  GLY C N     1 
ATOM   3861  C  CA    . GLY C 1 32  ? 175.255 217.597 196.921 1.00 20.35  ? 32  GLY C CA    1 
ATOM   3862  C  C     . GLY C 1 32  ? 175.514 218.771 195.973 1.00 21.71  ? 32  GLY C C     1 
ATOM   3863  O  O     . GLY C 1 32  ? 174.917 219.832 196.133 1.00 23.20  ? 32  GLY C O     1 
ATOM   3864  N  N     . GLN C 1 33  ? 176.409 218.587 194.998 1.00 22.99  ? 33  GLN C N     1 
ATOM   3865  C  CA    . GLN C 1 33  ? 176.738 219.628 194.037 1.00 23.03  ? 33  GLN C CA    1 
ATOM   3866  C  C     . GLN C 1 33  ? 175.891 219.532 192.770 1.00 22.88  ? 33  GLN C C     1 
ATOM   3867  O  O     . GLN C 1 33  ? 176.132 220.280 191.827 1.00 25.66  ? 33  GLN C O     1 
ATOM   3868  C  CB    . GLN C 1 33  ? 178.216 219.537 193.659 1.00 25.02  ? 33  GLN C CB    1 
ATOM   3869  C  CG    . GLN C 1 33  ? 179.181 219.816 194.803 1.00 26.49  ? 33  GLN C CG    1 
ATOM   3870  C  CD    . GLN C 1 33  ? 179.426 221.290 195.013 1.00 30.87  ? 33  GLN C CD    1 
ATOM   3871  O  OE1   . GLN C 1 33  ? 179.804 222.004 194.077 1.00 33.63  ? 33  GLN C OE1   1 
ATOM   3872  N  NE2   . GLN C 1 33  ? 179.246 221.758 196.242 1.00 33.03  ? 33  GLN C NE2   1 
ATOM   3873  N  N     . GLY C 1 34  ? 174.913 218.621 192.730 1.00 21.79  ? 34  GLY C N     1 
ATOM   3874  C  CA    . GLY C 1 34  ? 173.961 218.571 191.632 1.00 21.03  ? 34  GLY C CA    1 
ATOM   3875  C  C     . GLY C 1 34  ? 174.239 217.464 190.614 1.00 21.21  ? 34  GLY C C     1 
ATOM   3876  O  O     . GLY C 1 34  ? 173.571 217.416 189.584 1.00 21.59  ? 34  GLY C O     1 
ATOM   3877  N  N     . ALA C 1 35  ? 175.204 216.578 190.892 1.00 20.28  ? 35  ALA C N     1 
ATOM   3878  C  CA    . ALA C 1 35  ? 175.483 215.471 189.991 1.00 19.45  ? 35  ALA C CA    1 
ATOM   3879  C  C     . ALA C 1 35  ? 174.614 214.266 190.347 1.00 19.08  ? 35  ALA C C     1 
ATOM   3880  O  O     . ALA C 1 35  ? 173.994 214.212 191.404 1.00 18.95  ? 35  ALA C O     1 
ATOM   3881  C  CB    . ALA C 1 35  ? 176.951 215.113 190.020 1.00 20.33  ? 35  ALA C CB    1 
ATOM   3882  N  N     . SER C 1 36  ? 174.582 213.291 189.434 1.00 18.60  ? 36  SER C N     1 
ATOM   3883  C  CA    . SER C 1 36  ? 173.964 211.996 189.670 1.00 19.46  ? 36  SER C CA    1 
ATOM   3884  C  C     . SER C 1 36  ? 175.065 210.957 189.885 1.00 19.23  ? 36  SER C C     1 
ATOM   3885  O  O     . SER C 1 36  ? 176.074 210.961 189.175 1.00 19.04  ? 36  SER C O     1 
ATOM   3886  C  CB    . SER C 1 36  ? 173.065 211.590 188.532 1.00 19.82  ? 36  SER C CB    1 
ATOM   3887  O  OG    . SER C 1 36  ? 172.150 212.628 188.209 1.00 22.24  ? 36  SER C OG    1 
ATOM   3888  N  N     . ALA C 1 37  ? 174.860 210.076 190.869 1.00 18.37  ? 37  ALA C N     1 
ATOM   3889  C  CA    . ALA C 1 37  ? 175.856 209.081 191.228 1.00 19.10  ? 37  ALA C CA    1 
ATOM   3890  C  C     . ALA C 1 37  ? 175.258 207.681 191.128 1.00 19.31  ? 37  ALA C C     1 
ATOM   3891  O  O     . ALA C 1 37  ? 174.109 207.459 191.486 1.00 21.53  ? 37  ALA C O     1 
ATOM   3892  C  CB    . ALA C 1 37  ? 176.389 209.338 192.618 1.00 18.49  ? 37  ALA C CB    1 
ATOM   3893  N  N     . VAL C 1 38  ? 176.077 206.741 190.664 1.00 18.86  ? 38  VAL C N     1 
ATOM   3894  C  CA    . VAL C 1 38  ? 175.774 205.326 190.713 1.00 18.35  ? 38  VAL C CA    1 
ATOM   3895  C  C     . VAL C 1 38  ? 176.789 204.658 191.629 1.00 17.43  ? 38  VAL C C     1 
ATOM   3896  O  O     . VAL C 1 38  ? 177.982 204.657 191.344 1.00 17.67  ? 38  VAL C O     1 
ATOM   3897  C  CB    . VAL C 1 38  ? 175.801 204.714 189.307 1.00 19.24  ? 38  VAL C CB    1 
ATOM   3898  C  CG1   . VAL C 1 38  ? 175.597 203.208 189.360 1.00 19.96  ? 38  VAL C CG1   1 
ATOM   3899  C  CG2   . VAL C 1 38  ? 174.771 205.375 188.410 1.00 20.27  ? 38  VAL C CG2   1 
ATOM   3900  N  N     . LEU C 1 39  ? 176.306 204.097 192.737 1.00 16.77  ? 39  LEU C N     1 
ATOM   3901  C  CA    . LEU C 1 39  ? 177.174 203.414 193.681 1.00 17.09  ? 39  LEU C CA    1 
ATOM   3902  C  C     . LEU C 1 39  ? 177.392 201.981 193.207 1.00 16.74  ? 39  LEU C C     1 
ATOM   3903  O  O     . LEU C 1 39  ? 176.496 201.148 193.301 1.00 17.61  ? 39  LEU C O     1 
ATOM   3904  C  CB    . LEU C 1 39  ? 176.596 203.442 195.093 1.00 17.61  ? 39  LEU C CB    1 
ATOM   3905  C  CG    . LEU C 1 39  ? 176.183 204.815 195.620 1.00 17.91  ? 39  LEU C CG    1 
ATOM   3906  C  CD1   . LEU C 1 39  ? 175.762 204.709 197.081 1.00 18.08  ? 39  LEU C CD1   1 
ATOM   3907  C  CD2   . LEU C 1 39  ? 177.299 205.819 195.458 1.00 18.09  ? 39  LEU C CD2   1 
ATOM   3908  N  N     . LEU C 1 40  ? 178.603 201.706 192.711 1.00 16.19  ? 40  LEU C N     1 
ATOM   3909  C  CA    . LEU C 1 40  ? 178.996 200.371 192.295 1.00 16.16  ? 40  LEU C CA    1 
ATOM   3910  C  C     . LEU C 1 40  ? 179.788 199.746 193.441 1.00 16.99  ? 40  LEU C C     1 
ATOM   3911  O  O     . LEU C 1 40  ? 180.915 200.152 193.730 1.00 16.78  ? 40  LEU C O     1 
ATOM   3912  C  CB    . LEU C 1 40  ? 179.795 200.473 190.993 1.00 16.47  ? 40  LEU C CB    1 
ATOM   3913  C  CG    . LEU C 1 40  ? 180.007 199.193 190.181 1.00 16.88  ? 40  LEU C CG    1 
ATOM   3914  C  CD1   . LEU C 1 40  ? 180.337 199.526 188.754 1.00 16.26  ? 40  LEU C CD1   1 
ATOM   3915  C  CD2   . LEU C 1 40  ? 181.108 198.307 190.749 1.00 17.75  ? 40  LEU C CD2   1 
ATOM   3916  N  N     . ASP C 1 41  ? 179.177 198.764 194.106 1.00 17.71  ? 41  ASP C N     1 
ATOM   3917  C  CA    . ASP C 1 41  ? 179.819 198.081 195.214 1.00 19.66  ? 41  ASP C CA    1 
ATOM   3918  C  C     . ASP C 1 41  ? 179.240 196.676 195.346 1.00 19.03  ? 41  ASP C C     1 
ATOM   3919  O  O     . ASP C 1 41  ? 178.287 196.325 194.665 1.00 18.23  ? 41  ASP C O     1 
ATOM   3920  C  CB    . ASP C 1 41  ? 179.708 198.876 196.502 1.00 21.21  ? 41  ASP C CB    1 
ATOM   3921  C  CG    . ASP C 1 41  ? 180.852 198.636 197.482 1.00 24.23  ? 41  ASP C CG    1 
ATOM   3922  O  OD1   . ASP C 1 41  ? 181.469 197.543 197.435 1.00 24.70  ? 41  ASP C OD1   1 
ATOM   3923  O  OD2   . ASP C 1 41  ? 181.136 199.520 198.299 1.00 26.39  ? 41  ASP C OD2   1 
ATOM   3924  N  N     . LEU C 1 42  ? 179.844 195.874 196.220 1.00 19.81  ? 42  LEU C N     1 
ATOM   3925  C  CA    . LEU C 1 42  ? 179.446 194.491 196.394 1.00 20.80  ? 42  LEU C CA    1 
ATOM   3926  C  C     . LEU C 1 42  ? 178.030 194.428 196.956 1.00 21.58  ? 42  LEU C C     1 
ATOM   3927  O  O     . LEU C 1 42  ? 177.591 195.327 197.669 1.00 20.30  ? 42  LEU C O     1 
ATOM   3928  C  CB    . LEU C 1 42  ? 180.421 193.768 197.316 1.00 21.02  ? 42  LEU C CB    1 
ATOM   3929  C  CG    . LEU C 1 42  ? 181.837 193.573 196.774 1.00 21.23  ? 42  LEU C CG    1 
ATOM   3930  C  CD1   . LEU C 1 42  ? 182.762 193.071 197.865 1.00 22.23  ? 42  LEU C CD1   1 
ATOM   3931  C  CD2   . LEU C 1 42  ? 181.813 192.594 195.630 1.00 20.85  ? 42  LEU C CD2   1 
ATOM   3932  N  N     . PRO C 1 43  ? 177.270 193.353 196.652 1.00 23.74  ? 43  PRO C N     1 
ATOM   3933  C  CA    . PRO C 1 43  ? 175.929 193.193 197.222 1.00 26.04  ? 43  PRO C CA    1 
ATOM   3934  C  C     . PRO C 1 43  ? 175.891 193.200 198.750 1.00 28.31  ? 43  PRO C C     1 
ATOM   3935  O  O     . PRO C 1 43  ? 174.942 193.710 199.349 1.00 31.89  ? 43  PRO C O     1 
ATOM   3936  C  CB    . PRO C 1 43  ? 175.456 191.857 196.660 1.00 26.26  ? 43  PRO C CB    1 
ATOM   3937  C  CG    . PRO C 1 43  ? 176.296 191.642 195.425 1.00 25.93  ? 43  PRO C CG    1 
ATOM   3938  C  CD    . PRO C 1 43  ? 177.649 192.267 195.732 1.00 24.88  ? 43  PRO C CD    1 
ATOM   3939  N  N     . ASN C 1 44  ? 176.938 192.672 199.389 1.00 32.77  ? 44  ASN C N     1 
ATOM   3940  C  CA    . ASN C 1 44  ? 176.960 192.582 200.842 1.00 39.74  ? 44  ASN C CA    1 
ATOM   3941  C  C     . ASN C 1 44  ? 177.185 193.944 201.494 1.00 39.24  ? 44  ASN C C     1 
ATOM   3942  O  O     . ASN C 1 44  ? 176.968 194.078 202.695 1.00 42.73  ? 44  ASN C O     1 
ATOM   3943  C  CB    . ASN C 1 44  ? 177.998 191.583 201.332 1.00 44.44  ? 44  ASN C CB    1 
ATOM   3944  C  CG    . ASN C 1 44  ? 179.418 191.956 200.963 1.00 49.79  ? 44  ASN C CG    1 
ATOM   3945  O  OD1   . ASN C 1 44  ? 179.736 193.131 200.737 1.00 51.21  ? 44  ASN C OD1   1 
ATOM   3946  N  ND2   . ASN C 1 44  ? 180.296 190.966 200.915 1.00 54.51  ? 44  ASN C ND2   1 
ATOM   3947  N  N     . SER C 1 45  ? 177.619 194.952 200.716 1.00 37.38  ? 45  SER C N     1 
ATOM   3948  C  CA    . SER C 1 45  ? 177.804 196.288 201.250 1.00 36.69  ? 45  SER C CA    1 
ATOM   3949  C  C     . SER C 1 45  ? 176.437 196.920 201.513 1.00 35.96  ? 45  SER C C     1 
ATOM   3950  O  O     . SER C 1 45  ? 175.417 196.495 200.969 1.00 42.15  ? 45  SER C O     1 
ATOM   3951  C  CB    . SER C 1 45  ? 178.632 197.111 200.309 1.00 35.23  ? 45  SER C CB    1 
ATOM   3952  O  OG    . SER C 1 45  ? 177.942 197.396 199.108 1.00 32.16  ? 45  SER C OG    1 
ATOM   3953  N  N     . GLY C 1 46  ? 176.430 197.955 202.336 1.00 31.84  ? 46  GLY C N     1 
ATOM   3954  C  CA    . GLY C 1 46  ? 175.195 198.675 202.604 1.00 28.78  ? 46  GLY C CA    1 
ATOM   3955  C  C     . GLY C 1 46  ? 174.921 199.710 201.518 1.00 27.71  ? 46  GLY C C     1 
ATOM   3956  O  O     . GLY C 1 46  ? 174.481 200.829 201.815 1.00 28.47  ? 46  GLY C O     1 
ATOM   3957  N  N     . GLY C 1 47  ? 175.187 199.351 200.258 1.00 26.19  ? 47  GLY C N     1 
ATOM   3958  C  CA    . GLY C 1 47  ? 175.081 200.314 199.169 1.00 26.79  ? 47  GLY C CA    1 
ATOM   3959  C  C     . GLY C 1 47  ? 173.651 200.801 198.936 1.00 26.80  ? 47  GLY C C     1 
ATOM   3960  O  O     . GLY C 1 47  ? 173.430 201.977 198.646 1.00 25.95  ? 47  GLY C O     1 
ATOM   3961  N  N     . GLU C 1 48  ? 172.693 199.893 199.084 1.00 28.12  ? 48  GLU C N     1 
ATOM   3962  C  CA    . GLU C 1 48  ? 171.294 200.248 198.879 1.00 31.49  ? 48  GLU C CA    1 
ATOM   3963  C  C     . GLU C 1 48  ? 170.838 201.295 199.894 1.00 27.49  ? 48  GLU C C     1 
ATOM   3964  O  O     . GLU C 1 48  ? 170.130 202.236 199.546 1.00 28.39  ? 48  GLU C O     1 
ATOM   3965  C  CB    . GLU C 1 48  ? 170.354 199.047 198.877 1.00 39.29  ? 48  GLU C CB    1 
ATOM   3966  C  CG    . GLU C 1 48  ? 170.303 198.302 200.203 1.00 50.53  ? 48  GLU C CG    1 
ATOM   3967  C  CD    . GLU C 1 48  ? 171.448 197.327 200.434 1.00 59.16  ? 48  GLU C CD    1 
ATOM   3968  O  OE1   . GLU C 1 48  ? 172.461 197.341 199.696 1.00 55.11  ? 48  GLU C OE1   1 
ATOM   3969  O  OE2   . GLU C 1 48  ? 171.298 196.530 201.378 1.00 72.21  ? 48  GLU C OE2   1 
ATOM   3970  N  N     . ALA C 1 49  ? 171.239 201.145 201.153 1.00 26.26  ? 49  ALA C N     1 
ATOM   3971  C  CA    . ALA C 1 49  ? 170.887 202.110 202.186 1.00 25.54  ? 49  ALA C CA    1 
ATOM   3972  C  C     . ALA C 1 49  ? 171.549 203.458 201.912 1.00 25.39  ? 49  ALA C C     1 
ATOM   3973  O  O     . ALA C 1 49  ? 170.917 204.499 202.076 1.00 26.16  ? 49  ALA C O     1 
ATOM   3974  C  CB    . ALA C 1 49  ? 171.273 201.587 203.551 1.00 26.24  ? 49  ALA C CB    1 
ATOM   3975  N  N     . GLN C 1 50  ? 172.812 203.453 201.480 1.00 24.11  ? 50  GLN C N     1 
ATOM   3976  C  CA    . GLN C 1 50  ? 173.503 204.700 201.183 1.00 23.33  ? 50  GLN C CA    1 
ATOM   3977  C  C     . GLN C 1 50  ? 172.857 205.409 199.994 1.00 21.58  ? 50  GLN C C     1 
ATOM   3978  O  O     . GLN C 1 50  ? 172.692 206.629 200.016 1.00 22.46  ? 50  GLN C O     1 
ATOM   3979  C  CB    . GLN C 1 50  ? 174.983 204.448 200.895 1.00 24.40  ? 50  GLN C CB    1 
ATOM   3980  C  CG    . GLN C 1 50  ? 175.748 203.822 202.053 1.00 25.50  ? 50  GLN C CG    1 
ATOM   3981  C  CD    . GLN C 1 50  ? 175.593 204.589 203.345 1.00 27.17  ? 50  GLN C CD    1 
ATOM   3982  O  OE1   . GLN C 1 50  ? 175.617 205.825 203.365 1.00 28.40  ? 50  GLN C OE1   1 
ATOM   3983  N  NE2   . GLN C 1 50  ? 175.415 203.852 204.434 1.00 30.65  ? 50  GLN C NE2   1 
ATOM   3984  N  N     . ALA C 1 51  ? 172.489 204.656 198.953 1.00 21.25  ? 51  ALA C N     1 
ATOM   3985  C  CA    . ALA C 1 51  ? 171.867 205.252 197.781 1.00 22.87  ? 51  ALA C CA    1 
ATOM   3986  C  C     . ALA C 1 51  ? 170.521 205.880 198.144 1.00 25.21  ? 51  ALA C C     1 
ATOM   3987  O  O     . ALA C 1 51  ? 170.190 206.960 197.662 1.00 25.18  ? 51  ALA C O     1 
ATOM   3988  C  CB    . ALA C 1 51  ? 171.713 204.229 196.679 1.00 22.56  ? 51  ALA C CB    1 
ATOM   3989  N  N     . LYS C 1 52  ? 169.738 205.198 198.982 1.00 28.60  ? 52  LYS C N     1 
ATOM   3990  C  CA    . LYS C 1 52  ? 168.467 205.745 199.437 1.00 33.34  ? 52  LYS C CA    1 
ATOM   3991  C  C     . LYS C 1 52  ? 168.697 207.000 200.279 1.00 31.28  ? 52  LYS C C     1 
ATOM   3992  O  O     . LYS C 1 52  ? 167.934 207.958 200.192 1.00 32.79  ? 52  LYS C O     1 
ATOM   3993  C  CB    . LYS C 1 52  ? 167.682 204.698 200.230 1.00 39.34  ? 52  LYS C CB    1 
ATOM   3994  C  CG    . LYS C 1 52  ? 166.320 205.171 200.696 1.00 46.68  ? 52  LYS C CG    1 
ATOM   3995  C  CD    . LYS C 1 52  ? 165.477 204.046 201.282 1.00 53.93  ? 52  LYS C CD    1 
ATOM   3996  C  CE    . LYS C 1 52  ? 164.092 204.494 201.621 1.00 58.28  ? 52  LYS C CE    1 
ATOM   3997  N  NZ    . LYS C 1 52  ? 163.301 203.401 202.194 1.00 60.95  ? 52  LYS C NZ    1 
ATOM   3998  N  N     . LYS C 1 53  ? 169.752 207.001 201.096 1.00 31.05  ? 53  LYS C N     1 
ATOM   3999  C  CA    . LYS C 1 53  ? 170.060 208.152 201.930 1.00 31.66  ? 53  LYS C CA    1 
ATOM   4000  C  C     . LYS C 1 53  ? 170.421 209.369 201.076 1.00 30.71  ? 53  LYS C C     1 
ATOM   4001  O  O     . LYS C 1 53  ? 170.086 210.494 201.433 1.00 29.94  ? 53  LYS C O     1 
ATOM   4002  C  CB    . LYS C 1 53  ? 171.201 207.801 202.886 1.00 36.12  ? 53  LYS C CB    1 
ATOM   4003  C  CG    . LYS C 1 53  ? 171.582 208.894 203.848 1.00 40.51  ? 53  LYS C CG    1 
ATOM   4004  C  CD    . LYS C 1 53  ? 172.761 208.510 204.735 1.00 44.53  ? 53  LYS C CD    1 
ATOM   4005  C  CE    . LYS C 1 53  ? 172.483 207.319 205.602 1.00 50.97  ? 53  LYS C CE    1 
ATOM   4006  N  NZ    . LYS C 1 53  ? 173.610 207.033 206.499 1.00 54.46  ? 53  LYS C NZ    1 
ATOM   4007  N  N     . LEU C 1 54  ? 171.095 209.152 199.944 1.00 28.88  ? 54  LEU C N     1 
ATOM   4008  C  CA    . LEU C 1 54  ? 171.569 210.254 199.122 1.00 28.48  ? 54  LEU C CA    1 
ATOM   4009  C  C     . LEU C 1 54  ? 170.482 210.843 198.233 1.00 26.83  ? 54  LEU C C     1 
ATOM   4010  O  O     . LEU C 1 54  ? 170.693 211.909 197.656 1.00 27.43  ? 54  LEU C O     1 
ATOM   4011  C  CB    . LEU C 1 54  ? 172.765 209.812 198.281 1.00 28.73  ? 54  LEU C CB    1 
ATOM   4012  C  CG    . LEU C 1 54  ? 174.065 209.602 199.052 1.00 31.15  ? 54  LEU C CG    1 
ATOM   4013  C  CD1   . LEU C 1 54  ? 175.208 209.296 198.106 1.00 31.78  ? 54  LEU C CD1   1 
ATOM   4014  C  CD2   . LEU C 1 54  ? 174.379 210.798 199.925 1.00 32.87  ? 54  LEU C CD2   1 
ATOM   4015  N  N     . GLY C 1 55  ? 169.344 210.155 198.092 1.00 26.41  ? 55  GLY C N     1 
ATOM   4016  C  CA    . GLY C 1 55  ? 168.199 210.713 197.388 1.00 26.47  ? 55  GLY C CA    1 
ATOM   4017  C  C     . GLY C 1 55  ? 168.007 210.100 196.008 1.00 26.54  ? 55  GLY C C     1 
ATOM   4018  O  O     . GLY C 1 55  ? 168.593 209.076 195.678 1.00 28.72  ? 55  GLY C O     1 
ATOM   4019  N  N     . ASN C 1 56  ? 167.167 210.752 195.204 1.00 27.06  ? 56  ASN C N     1 
ATOM   4020  C  CA    . ASN C 1 56  ? 166.734 210.211 193.929 1.00 30.53  ? 56  ASN C CA    1 
ATOM   4021  C  C     . ASN C 1 56  ? 167.822 210.321 192.862 1.00 29.24  ? 56  ASN C C     1 
ATOM   4022  O  O     . ASN C 1 56  ? 167.711 209.696 191.809 1.00 29.53  ? 56  ASN C O     1 
ATOM   4023  C  CB    . ASN C 1 56  ? 165.448 210.891 193.467 1.00 34.76  ? 56  ASN C CB    1 
ATOM   4024  C  CG    . ASN C 1 56  ? 164.263 210.448 194.293 1.00 40.36  ? 56  ASN C CG    1 
ATOM   4025  O  OD1   . ASN C 1 56  ? 164.167 209.262 194.633 1.00 41.68  ? 56  ASN C OD1   1 
ATOM   4026  N  ND2   . ASN C 1 56  ? 163.371 211.369 194.644 1.00 43.93  ? 56  ASN C ND2   1 
ATOM   4027  N  N     . ASN C 1 57  ? 168.841 211.150 193.098 1.00 28.13  ? 57  ASN C N     1 
ATOM   4028  C  CA    . ASN C 1 57  ? 169.930 211.299 192.144 1.00 28.36  ? 57  ASN C CA    1 
ATOM   4029  C  C     . ASN C 1 57  ? 171.040 210.278 192.398 1.00 25.88  ? 57  ASN C C     1 
ATOM   4030  O  O     . ASN C 1 57  ? 172.095 210.376 191.779 1.00 25.58  ? 57  ASN C O     1 
ATOM   4031  C  CB    . ASN C 1 57  ? 170.505 212.712 192.168 1.00 29.44  ? 57  ASN C CB    1 
ATOM   4032  C  CG    . ASN C 1 57  ? 169.578 213.715 191.525 1.00 32.85  ? 57  ASN C CG    1 
ATOM   4033  O  OD1   . ASN C 1 57  ? 169.117 213.504 190.399 1.00 34.34  ? 57  ASN C OD1   1 
ATOM   4034  N  ND2   . ASN C 1 57  ? 169.294 214.816 192.207 1.00 35.98  ? 57  ASN C ND2   1 
ATOM   4035  N  N     . CYS C 1 58  ? 170.825 209.321 193.303 1.00 24.03  ? 58  CYS C N     1 
ATOM   4036  C  CA    . CYS C 1 58  ? 171.796 208.280 193.590 1.00 23.21  ? 58  CYS C CA    1 
ATOM   4037  C  C     . CYS C 1 58  ? 171.107 206.919 193.536 1.00 22.56  ? 58  CYS C C     1 
ATOM   4038  O  O     . CYS C 1 58  ? 170.034 206.738 194.112 1.00 24.81  ? 58  CYS C O     1 
ATOM   4039  C  CB    . CYS C 1 58  ? 172.423 208.493 194.963 1.00 23.07  ? 58  CYS C CB    1 
ATOM   4040  S  SG    . CYS C 1 58  ? 173.825 207.400 195.303 1.00 24.46  ? 58  CYS C SG    1 
ATOM   4041  N  N     . VAL C 1 59  ? 171.740 205.970 192.842 1.00 20.64  ? 59  VAL C N     1 
ATOM   4042  C  CA    . VAL C 1 59  ? 171.240 204.612 192.748 1.00 21.13  ? 59  VAL C CA    1 
ATOM   4043  C  C     . VAL C 1 59  ? 172.375 203.648 193.065 1.00 20.69  ? 59  VAL C C     1 
ATOM   4044  O  O     . VAL C 1 59  ? 173.552 203.953 192.855 1.00 20.08  ? 59  VAL C O     1 
ATOM   4045  C  CB    . VAL C 1 59  ? 170.659 204.336 191.354 1.00 23.72  ? 59  VAL C CB    1 
ATOM   4046  C  CG1   . VAL C 1 59  ? 171.740 204.317 190.286 1.00 23.68  ? 59  VAL C CG1   1 
ATOM   4047  C  CG2   . VAL C 1 59  ? 169.876 203.040 191.306 1.00 26.83  ? 59  VAL C CG2   1 
ATOM   4048  N  N     . PHE C 1 60  ? 172.006 202.485 193.603 1.00 20.36  ? 60  PHE C N     1 
ATOM   4049  C  CA    . PHE C 1 60  ? 172.964 201.451 193.948 1.00 20.83  ? 60  PHE C CA    1 
ATOM   4050  C  C     . PHE C 1 60  ? 172.985 200.394 192.851 1.00 21.11  ? 60  PHE C C     1 
ATOM   4051  O  O     . PHE C 1 60  ? 171.948 199.842 192.498 1.00 23.60  ? 60  PHE C O     1 
ATOM   4052  C  CB    . PHE C 1 60  ? 172.605 200.831 195.295 1.00 21.32  ? 60  PHE C CB    1 
ATOM   4053  C  CG    . PHE C 1 60  ? 173.443 199.615 195.628 1.00 22.41  ? 60  PHE C CG    1 
ATOM   4054  C  CD1   . PHE C 1 60  ? 174.833 199.693 195.644 1.00 22.62  ? 60  PHE C CD1   1 
ATOM   4055  C  CD2   . PHE C 1 60  ? 172.833 198.402 195.912 1.00 22.64  ? 60  PHE C CD2   1 
ATOM   4056  C  CE1   . PHE C 1 60  ? 175.590 198.579 195.972 1.00 22.69  ? 60  PHE C CE1   1 
ATOM   4057  C  CE2   . PHE C 1 60  ? 173.595 197.292 196.225 1.00 24.34  ? 60  PHE C CE2   1 
ATOM   4058  C  CZ    . PHE C 1 60  ? 174.972 197.384 196.263 1.00 23.94  ? 60  PHE C CZ    1 
ATOM   4059  N  N     . ALA C 1 61  ? 174.183 200.106 192.334 1.00 20.73  ? 61  ALA C N     1 
ATOM   4060  C  CA    . ALA C 1 61  ? 174.373 199.060 191.342 1.00 20.50  ? 61  ALA C CA    1 
ATOM   4061  C  C     . ALA C 1 61  ? 175.283 197.993 191.921 1.00 20.96  ? 61  ALA C C     1 
ATOM   4062  O  O     . ALA C 1 61  ? 176.496 198.167 191.954 1.00 22.72  ? 61  ALA C O     1 
ATOM   4063  C  CB    . ALA C 1 61  ? 174.951 199.622 190.060 1.00 20.47  ? 61  ALA C CB    1 
ATOM   4064  N  N     . PRO C 1 62  ? 174.738 196.856 192.400 1.00 22.50  ? 62  PRO C N     1 
ATOM   4065  C  CA    . PRO C 1 62  ? 175.573 195.800 192.966 1.00 22.18  ? 62  PRO C CA    1 
ATOM   4066  C  C     . PRO C 1 62  ? 176.434 195.170 191.881 1.00 21.51  ? 62  PRO C C     1 
ATOM   4067  O  O     . PRO C 1 62  ? 175.932 194.747 190.844 1.00 24.24  ? 62  PRO C O     1 
ATOM   4068  C  CB    . PRO C 1 62  ? 174.568 194.807 193.558 1.00 22.51  ? 62  PRO C CB    1 
ATOM   4069  C  CG    . PRO C 1 62  ? 173.316 195.045 192.761 1.00 22.57  ? 62  PRO C CG    1 
ATOM   4070  C  CD    . PRO C 1 62  ? 173.306 196.518 192.434 1.00 22.67  ? 62  PRO C CD    1 
ATOM   4071  N  N     . ALA C 1 63  ? 177.741 195.108 192.132 1.00 21.55  ? 63  ALA C N     1 
ATOM   4072  C  CA    . ALA C 1 63  ? 178.658 194.524 191.169 1.00 20.32  ? 63  ALA C CA    1 
ATOM   4073  C  C     . ALA C 1 63  ? 179.966 194.181 191.857 1.00 20.56  ? 63  ALA C C     1 
ATOM   4074  O  O     . ALA C 1 63  ? 180.347 194.808 192.841 1.00 19.14  ? 63  ALA C O     1 
ATOM   4075  C  CB    . ALA C 1 63  ? 178.879 195.459 189.994 1.00 20.50  ? 63  ALA C CB    1 
ATOM   4076  N  N     . ASP C 1 64  ? 180.648 193.183 191.300 1.00 20.56  ? 64  ASP C N     1 
ATOM   4077  C  CA    . ASP C 1 64  ? 182.027 192.889 191.632 1.00 22.28  ? 64  ASP C CA    1 
ATOM   4078  C  C     . ASP C 1 64  ? 182.903 193.411 190.497 1.00 18.97  ? 64  ASP C C     1 
ATOM   4079  O  O     . ASP C 1 64  ? 182.725 193.015 189.351 1.00 19.38  ? 64  ASP C O     1 
ATOM   4080  C  CB    . ASP C 1 64  ? 182.197 191.397 191.844 1.00 24.81  ? 64  ASP C CB    1 
ATOM   4081  C  CG    . ASP C 1 64  ? 183.586 190.971 192.282 1.00 29.34  ? 64  ASP C CG    1 
ATOM   4082  O  OD1   . ASP C 1 64  ? 184.521 191.797 192.185 1.00 31.73  ? 64  ASP C OD1   1 
ATOM   4083  O  OD2   . ASP C 1 64  ? 183.712 189.809 192.724 1.00 32.06  ? 64  ASP C OD2   1 
ATOM   4084  N  N     . VAL C 1 65  ? 183.865 194.272 190.832 1.00 18.04  ? 65  VAL C N     1 
ATOM   4085  C  CA    . VAL C 1 65  ? 184.675 194.935 189.819 1.00 17.55  ? 65  VAL C CA    1 
ATOM   4086  C  C     . VAL C 1 65  ? 185.551 193.936 189.065 1.00 16.99  ? 65  VAL C C     1 
ATOM   4087  O  O     . VAL C 1 65  ? 185.933 194.194 187.929 1.00 17.96  ? 65  VAL C O     1 
ATOM   4088  C  CB    . VAL C 1 65  ? 185.536 196.048 190.435 1.00 17.77  ? 65  VAL C CB    1 
ATOM   4089  C  CG1   . VAL C 1 65  ? 184.659 197.155 190.953 1.00 18.45  ? 65  VAL C CG1   1 
ATOM   4090  C  CG2   . VAL C 1 65  ? 186.427 195.544 191.553 1.00 17.90  ? 65  VAL C CG2   1 
ATOM   4091  N  N     . THR C 1 66  ? 185.850 192.792 189.685 1.00 19.65  ? 66  THR C N     1 
ATOM   4092  C  CA    . THR C 1 66  ? 186.649 191.764 189.022 1.00 22.07  ? 66  THR C CA    1 
ATOM   4093  C  C     . THR C 1 66  ? 185.853 191.033 187.939 1.00 22.59  ? 66  THR C C     1 
ATOM   4094  O  O     . THR C 1 66  ? 186.431 190.277 187.166 1.00 25.03  ? 66  THR C O     1 
ATOM   4095  C  CB    . THR C 1 66  ? 187.184 190.775 190.050 1.00 21.98  ? 66  THR C CB    1 
ATOM   4096  O  OG1   . THR C 1 66  ? 186.095 190.055 190.610 1.00 23.04  ? 66  THR C OG1   1 
ATOM   4097  C  CG2   . THR C 1 66  ? 187.969 191.474 191.143 1.00 22.90  ? 66  THR C CG2   1 
ATOM   4098  N  N     . SER C 1 67  ? 184.529 191.240 187.885 1.00 22.44  ? 67  SER C N     1 
ATOM   4099  C  CA    . SER C 1 67  ? 183.669 190.533 186.949 1.00 23.11  ? 67  SER C CA    1 
ATOM   4100  C  C     . SER C 1 67  ? 183.272 191.456 185.804 1.00 23.53  ? 67  SER C C     1 
ATOM   4101  O  O     . SER C 1 67  ? 182.714 192.512 186.039 1.00 22.87  ? 67  SER C O     1 
ATOM   4102  C  CB    . SER C 1 67  ? 182.447 189.996 187.657 1.00 22.93  ? 67  SER C CB    1 
ATOM   4103  O  OG    . SER C 1 67  ? 181.508 189.465 186.735 1.00 23.49  ? 67  SER C OG    1 
ATOM   4104  N  N     . GLU C 1 68  ? 183.550 191.037 184.568 1.00 25.27  ? 68  GLU C N     1 
ATOM   4105  C  CA    . GLU C 1 68  ? 183.120 191.770 183.390 1.00 28.08  ? 68  GLU C CA    1 
ATOM   4106  C  C     . GLU C 1 68  ? 181.594 191.844 183.328 1.00 27.20  ? 68  GLU C C     1 
ATOM   4107  O  O     . GLU C 1 68  ? 181.033 192.897 183.039 1.00 27.49  ? 68  GLU C O     1 
ATOM   4108  C  CB    . GLU C 1 68  ? 183.671 191.112 182.129 1.00 33.42  ? 68  GLU C CB    1 
ATOM   4109  C  CG    . GLU C 1 68  ? 183.206 191.794 180.845 1.00 38.18  ? 68  GLU C CG    1 
ATOM   4110  C  CD    . GLU C 1 68  ? 183.903 191.265 179.602 1.00 42.46  ? 68  GLU C CD    1 
ATOM   4111  O  OE1   . GLU C 1 68  ? 184.649 192.071 178.994 1.00 43.35  ? 68  GLU C OE1   1 
ATOM   4112  O  OE2   . GLU C 1 68  ? 183.726 190.068 179.264 1.00 45.30  ? 68  GLU C OE2   1 
ATOM   4113  N  N     . LYS C 1 69  ? 180.915 190.734 183.621 1.00 28.32  ? 69  LYS C N     1 
ATOM   4114  C  CA    . LYS C 1 69  ? 179.463 190.695 183.555 1.00 29.82  ? 69  LYS C CA    1 
ATOM   4115  C  C     . LYS C 1 69  ? 178.837 191.628 184.594 1.00 25.74  ? 69  LYS C C     1 
ATOM   4116  O  O     . LYS C 1 69  ? 177.873 192.326 184.300 1.00 25.47  ? 69  LYS C O     1 
ATOM   4117  C  CB    . LYS C 1 69  ? 178.974 189.260 183.754 1.00 35.17  ? 69  LYS C CB    1 
ATOM   4118  C  CG    . LYS C 1 69  ? 177.471 189.097 183.692 1.00 43.29  ? 69  LYS C CG    1 
ATOM   4119  C  CD    . LYS C 1 69  ? 177.039 187.650 183.902 1.00 50.85  ? 69  LYS C CD    1 
ATOM   4120  C  CE    . LYS C 1 69  ? 177.403 187.136 185.268 1.00 56.74  ? 69  LYS C CE    1 
ATOM   4121  N  NZ    . LYS C 1 69  ? 176.944 185.762 185.477 1.00 60.68  ? 69  LYS C NZ    1 
ATOM   4122  N  N     . ASP C 1 70  ? 179.383 191.634 185.814 1.00 24.95  ? 70  ASP C N     1 
ATOM   4123  C  CA    . ASP C 1 70  ? 178.858 192.470 186.880 1.00 23.94  ? 70  ASP C CA    1 
ATOM   4124  C  C     . ASP C 1 70  ? 178.964 193.947 186.519 1.00 21.95  ? 70  ASP C C     1 
ATOM   4125  O  O     . ASP C 1 70  ? 178.016 194.707 186.707 1.00 21.10  ? 70  ASP C O     1 
ATOM   4126  C  CB    . ASP C 1 70  ? 179.555 192.190 188.201 1.00 27.60  ? 70  ASP C CB    1 
ATOM   4127  C  CG    . ASP C 1 70  ? 178.961 191.032 188.977 1.00 33.15  ? 70  ASP C CG    1 
ATOM   4128  O  OD1   . ASP C 1 70  ? 179.264 190.929 190.190 1.00 37.25  ? 70  ASP C OD1   1 
ATOM   4129  O  OD2   . ASP C 1 70  ? 178.173 190.263 188.370 1.00 38.54  ? 70  ASP C OD2   1 
ATOM   4130  N  N     . VAL C 1 71  ? 180.121 194.363 185.998 1.00 18.92  ? 71  VAL C N     1 
ATOM   4131  C  CA    . VAL C 1 71  ? 180.323 195.762 185.666 1.00 18.37  ? 71  VAL C CA    1 
ATOM   4132  C  C     . VAL C 1 71  ? 179.443 196.149 184.486 1.00 18.89  ? 71  VAL C C     1 
ATOM   4133  O  O     . VAL C 1 71  ? 178.896 197.252 184.453 1.00 20.49  ? 71  VAL C O     1 
ATOM   4134  C  CB    . VAL C 1 71  ? 181.809 196.058 185.395 1.00 17.81  ? 71  VAL C CB    1 
ATOM   4135  C  CG1   . VAL C 1 71  ? 182.025 197.492 184.940 1.00 17.20  ? 71  VAL C CG1   1 
ATOM   4136  C  CG2   . VAL C 1 71  ? 182.654 195.754 186.624 1.00 17.32  ? 71  VAL C CG2   1 
ATOM   4137  N  N     . GLN C 1 72  ? 179.296 195.246 183.512 1.00 20.82  ? 72  GLN C N     1 
ATOM   4138  C  CA    . GLN C 1 72  ? 178.426 195.504 182.373 1.00 21.64  ? 72  GLN C CA    1 
ATOM   4139  C  C     . GLN C 1 72  ? 176.989 195.726 182.839 1.00 20.92  ? 72  GLN C C     1 
ATOM   4140  O  O     . GLN C 1 72  ? 176.307 196.618 182.340 1.00 21.30  ? 72  GLN C O     1 
ATOM   4141  C  CB    . GLN C 1 72  ? 178.501 194.362 181.361 1.00 23.42  ? 72  GLN C CB    1 
ATOM   4142  C  CG    . GLN C 1 72  ? 179.748 194.395 180.488 1.00 25.84  ? 72  GLN C CG    1 
ATOM   4143  C  CD    . GLN C 1 72  ? 179.853 193.194 179.572 1.00 28.00  ? 72  GLN C CD    1 
ATOM   4144  O  OE1   . GLN C 1 72  ? 179.433 192.083 179.913 1.00 28.40  ? 72  GLN C OE1   1 
ATOM   4145  N  NE2   . GLN C 1 72  ? 180.419 193.407 178.393 1.00 30.89  ? 72  GLN C NE2   1 
ATOM   4146  N  N     . THR C 1 73  ? 176.521 194.903 183.781 1.00 21.06  ? 73  THR C N     1 
ATOM   4147  C  CA    . THR C 1 73  ? 175.179 195.061 184.325 1.00 22.65  ? 73  THR C CA    1 
ATOM   4148  C  C     . THR C 1 73  ? 175.044 196.402 185.049 1.00 21.99  ? 73  THR C C     1 
ATOM   4149  O  O     . THR C 1 73  ? 174.038 197.092 184.898 1.00 22.86  ? 73  THR C O     1 
ATOM   4150  C  CB    . THR C 1 73  ? 174.847 193.904 185.267 1.00 25.11  ? 73  THR C CB    1 
ATOM   4151  O  OG1   . THR C 1 73  ? 175.004 192.683 184.552 1.00 26.35  ? 73  THR C OG1   1 
ATOM   4152  C  CG2   . THR C 1 73  ? 173.430 194.009 185.794 1.00 26.09  ? 73  THR C CG2   1 
ATOM   4153  N  N     . ALA C 1 74  ? 176.059 196.772 185.840 1.00 21.24  ? 74  ALA C N     1 
ATOM   4154  C  CA    . ALA C 1 74  ? 176.025 198.024 186.581 1.00 21.07  ? 74  ALA C CA    1 
ATOM   4155  C  C     . ALA C 1 74  ? 175.985 199.225 185.633 1.00 20.27  ? 74  ALA C C     1 
ATOM   4156  O  O     . ALA C 1 74  ? 175.235 200.173 185.855 1.00 20.17  ? 74  ALA C O     1 
ATOM   4157  C  CB    . ALA C 1 74  ? 177.208 198.112 187.528 1.00 20.45  ? 74  ALA C CB    1 
ATOM   4158  N  N     . LEU C 1 75  ? 176.793 199.186 184.571 1.00 20.45  ? 75  LEU C N     1 
ATOM   4159  C  CA    . LEU C 1 75  ? 176.834 200.293 183.628 1.00 21.62  ? 75  LEU C CA    1 
ATOM   4160  C  C     . LEU C 1 75  ? 175.525 200.386 182.847 1.00 22.62  ? 75  LEU C C     1 
ATOM   4161  O  O     . LEU C 1 75  ? 175.079 201.490 182.533 1.00 23.91  ? 75  LEU C O     1 
ATOM   4162  C  CB    . LEU C 1 75  ? 178.026 200.152 182.695 1.00 21.81  ? 75  LEU C CB    1 
ATOM   4163  C  CG    . LEU C 1 75  ? 179.386 200.405 183.346 1.00 22.86  ? 75  LEU C CG    1 
ATOM   4164  C  CD1   . LEU C 1 75  ? 180.511 199.934 182.458 1.00 22.49  ? 75  LEU C CD1   1 
ATOM   4165  C  CD2   . LEU C 1 75  ? 179.515 201.889 183.618 1.00 23.78  ? 75  LEU C CD2   1 
ATOM   4166  N  N     . ALA C 1 76  ? 174.914 199.237 182.538 1.00 23.28  ? 76  ALA C N     1 
ATOM   4167  C  CA    . ALA C 1 76  ? 173.609 199.234 181.891 1.00 23.94  ? 76  ALA C CA    1 
ATOM   4168  C  C     . ALA C 1 76  ? 172.562 199.864 182.806 1.00 24.87  ? 76  ALA C C     1 
ATOM   4169  O  O     . ALA C 1 76  ? 171.683 200.585 182.339 1.00 26.10  ? 76  ALA C O     1 
ATOM   4170  C  CB    . ALA C 1 76  ? 173.217 197.829 181.495 1.00 23.98  ? 76  ALA C CB    1 
ATOM   4171  N  N     . LEU C 1 77  ? 172.656 199.590 184.111 1.00 25.04  ? 77  LEU C N     1 
ATOM   4172  C  CA    . LEU C 1 77  ? 171.772 200.214 185.082 1.00 26.93  ? 77  LEU C CA    1 
ATOM   4173  C  C     . LEU C 1 77  ? 171.985 201.726 185.099 1.00 26.33  ? 77  LEU C C     1 
ATOM   4174  O  O     . LEU C 1 77  ? 171.019 202.482 185.179 1.00 26.41  ? 77  LEU C O     1 
ATOM   4175  C  CB    . LEU C 1 77  ? 172.003 199.580 186.454 1.00 28.70  ? 77  LEU C CB    1 
ATOM   4176  C  CG    . LEU C 1 77  ? 171.075 199.984 187.604 1.00 31.18  ? 77  LEU C CG    1 
ATOM   4177  C  CD1   . LEU C 1 77  ? 170.929 198.823 188.567 1.00 33.23  ? 77  LEU C CD1   1 
ATOM   4178  C  CD2   . LEU C 1 77  ? 171.589 201.189 188.362 1.00 32.54  ? 77  LEU C CD2   1 
ATOM   4179  N  N     . ALA C 1 78  ? 173.248 202.167 185.033 1.00 26.98  ? 78  ALA C N     1 
ATOM   4180  C  CA    . ALA C 1 78  ? 173.552 203.591 185.006 1.00 26.53  ? 78  ALA C CA    1 
ATOM   4181  C  C     . ALA C 1 78  ? 172.951 204.255 183.769 1.00 27.43  ? 78  ALA C C     1 
ATOM   4182  O  O     . ALA C 1 78  ? 172.382 205.336 183.863 1.00 28.06  ? 78  ALA C O     1 
ATOM   4183  C  CB    . ALA C 1 78  ? 175.049 203.820 185.076 1.00 27.19  ? 78  ALA C CB    1 
ATOM   4184  N  N     . LYS C 1 79  ? 173.096 203.615 182.604 1.00 31.23  ? 79  LYS C N     1 
ATOM   4185  C  CA    . LYS C 1 79  ? 172.544 204.163 181.373 1.00 34.53  ? 79  LYS C CA    1 
ATOM   4186  C  C     . LYS C 1 79  ? 171.015 204.187 181.436 1.00 31.96  ? 79  LYS C C     1 
ATOM   4187  O  O     . LYS C 1 79  ? 170.390 205.151 180.988 1.00 31.58  ? 79  LYS C O     1 
ATOM   4188  C  CB    . LYS C 1 79  ? 173.017 203.376 180.152 1.00 42.04  ? 79  LYS C CB    1 
ATOM   4189  C  CG    . LYS C 1 79  ? 172.559 203.953 178.827 1.00 51.40  ? 79  LYS C CG    1 
ATOM   4190  C  CD    . LYS C 1 79  ? 172.956 203.131 177.613 1.00 58.16  ? 79  LYS C CD    1 
ATOM   4191  C  CE    . LYS C 1 79  ? 174.416 203.261 177.336 1.00 64.80  ? 79  LYS C CE    1 
ATOM   4192  N  NZ    . LYS C 1 79  ? 174.863 202.573 176.117 1.00 66.31  ? 79  LYS C NZ    1 
ATOM   4193  N  N     . GLY C 1 80  ? 170.410 203.124 181.975 1.00 30.89  ? 80  GLY C N     1 
ATOM   4194  C  CA    . GLY C 1 80  ? 168.960 203.062 182.070 1.00 30.09  ? 80  GLY C CA    1 
ATOM   4195  C  C     . GLY C 1 80  ? 168.397 204.142 182.994 1.00 30.51  ? 80  GLY C C     1 
ATOM   4196  O  O     . GLY C 1 80  ? 167.387 204.773 182.697 1.00 33.45  ? 80  GLY C O     1 
ATOM   4197  N  N     . LYS C 1 81  ? 169.063 204.359 184.129 1.00 29.88  ? 81  LYS C N     1 
ATOM   4198  C  CA    . LYS C 1 81  ? 168.570 205.290 185.129 1.00 29.10  ? 81  LYS C CA    1 
ATOM   4199  C  C     . LYS C 1 81  ? 168.830 206.739 184.714 1.00 28.48  ? 81  LYS C C     1 
ATOM   4200  O  O     . LYS C 1 81  ? 167.959 207.585 184.876 1.00 27.24  ? 81  LYS C O     1 
ATOM   4201  C  CB    . LYS C 1 81  ? 169.230 204.976 186.472 1.00 31.38  ? 81  LYS C CB    1 
ATOM   4202  C  CG    . LYS C 1 81  ? 168.879 205.934 187.580 1.00 35.09  ? 81  LYS C CG    1 
ATOM   4203  C  CD    . LYS C 1 81  ? 167.390 205.995 187.897 1.00 38.75  ? 81  LYS C CD    1 
ATOM   4204  C  CE    . LYS C 1 81  ? 167.169 206.597 189.253 1.00 42.23  ? 81  LYS C CE    1 
ATOM   4205  N  NZ    . LYS C 1 81  ? 165.837 207.181 189.401 1.00 44.02  ? 81  LYS C NZ    1 
ATOM   4206  N  N     . PHE C 1 82  ? 170.038 207.036 184.218 1.00 26.70  ? 82  PHE C N     1 
ATOM   4207  C  CA    . PHE C 1 82  ? 170.464 208.420 184.035 1.00 25.62  ? 82  PHE C CA    1 
ATOM   4208  C  C     . PHE C 1 82  ? 170.783 208.776 182.586 1.00 24.43  ? 82  PHE C C     1 
ATOM   4209  O  O     . PHE C 1 82  ? 170.947 209.956 182.293 1.00 26.08  ? 82  PHE C O     1 
ATOM   4210  C  CB    . PHE C 1 82  ? 171.699 208.706 184.886 1.00 24.88  ? 82  PHE C CB    1 
ATOM   4211  C  CG    . PHE C 1 82  ? 171.429 208.633 186.373 1.00 23.73  ? 82  PHE C CG    1 
ATOM   4212  C  CD1   . PHE C 1 82  ? 170.438 209.417 186.949 1.00 24.03  ? 82  PHE C CD1   1 
ATOM   4213  C  CD2   . PHE C 1 82  ? 172.139 207.759 187.180 1.00 24.39  ? 82  PHE C CD2   1 
ATOM   4214  C  CE1   . PHE C 1 82  ? 170.199 209.356 188.310 1.00 24.40  ? 82  PHE C CE1   1 
ATOM   4215  C  CE2   . PHE C 1 82  ? 171.873 207.685 188.534 1.00 24.26  ? 82  PHE C CE2   1 
ATOM   4216  C  CZ    . PHE C 1 82  ? 170.911 208.487 189.095 1.00 24.41  ? 82  PHE C CZ    1 
ATOM   4217  N  N     . GLY C 1 83  ? 170.917 207.790 181.693 1.00 24.48  ? 83  GLY C N     1 
ATOM   4218  C  CA    . GLY C 1 83  ? 171.011 208.072 180.268 1.00 24.69  ? 83  GLY C CA    1 
ATOM   4219  C  C     . GLY C 1 83  ? 172.447 208.121 179.747 1.00 25.52  ? 83  GLY C C     1 
ATOM   4220  O  O     . GLY C 1 83  ? 172.667 207.981 178.544 1.00 26.20  ? 83  GLY C O     1 
ATOM   4221  N  N     . ARG C 1 84  ? 173.427 208.354 180.628 1.00 24.33  ? 84  ARG C N     1 
ATOM   4222  C  CA    . ARG C 1 84  ? 174.808 208.472 180.197 1.00 23.31  ? 84  ARG C CA    1 
ATOM   4223  C  C     . ARG C 1 84  ? 175.728 208.294 181.398 1.00 20.35  ? 84  ARG C C     1 
ATOM   4224  O  O     . ARG C 1 84  ? 175.276 208.283 182.540 1.00 20.50  ? 84  ARG C O     1 
ATOM   4225  C  CB    . ARG C 1 84  ? 175.039 209.833 179.537 1.00 24.75  ? 84  ARG C CB    1 
ATOM   4226  C  CG    . ARG C 1 84  ? 174.886 211.011 180.489 1.00 27.91  ? 84  ARG C CG    1 
ATOM   4227  C  CD    . ARG C 1 84  ? 174.783 212.332 179.751 1.00 30.92  ? 84  ARG C CD    1 
ATOM   4228  N  NE    . ARG C 1 84  ? 176.097 212.872 179.393 1.00 33.06  ? 84  ARG C NE    1 
ATOM   4229  C  CZ    . ARG C 1 84  ? 176.511 213.184 178.172 1.00 36.38  ? 84  ARG C CZ    1 
ATOM   4230  N  NH1   . ARG C 1 84  ? 175.760 212.916 177.120 1.00 39.21  ? 84  ARG C NH1   1 
ATOM   4231  N  NH2   . ARG C 1 84  ? 177.713 213.693 177.991 1.00 35.29  ? 84  ARG C NH2   1 
ATOM   4232  N  N     . VAL C 1 85  ? 177.026 208.186 181.105 1.00 18.48  ? 85  VAL C N     1 
ATOM   4233  C  CA    . VAL C 1 85  ? 178.060 208.204 182.122 1.00 17.32  ? 85  VAL C CA    1 
ATOM   4234  C  C     . VAL C 1 85  ? 179.085 209.261 181.731 1.00 15.71  ? 85  VAL C C     1 
ATOM   4235  O  O     . VAL C 1 85  ? 179.658 209.189 180.658 1.00 15.82  ? 85  VAL C O     1 
ATOM   4236  C  CB    . VAL C 1 85  ? 178.709 206.824 182.307 1.00 17.00  ? 85  VAL C CB    1 
ATOM   4237  C  CG1   . VAL C 1 85  ? 179.868 206.890 183.295 1.00 16.58  ? 85  VAL C CG1   1 
ATOM   4238  C  CG2   . VAL C 1 85  ? 177.686 205.793 182.763 1.00 17.39  ? 85  VAL C CG2   1 
ATOM   4239  N  N     . ASP C 1 86  ? 179.338 210.210 182.638 1.00 14.97  ? 86  ASP C N     1 
ATOM   4240  C  CA    . ASP C 1 86  ? 180.281 211.292 182.389 1.00 14.57  ? 86  ASP C CA    1 
ATOM   4241  C  C     . ASP C 1 86  ? 181.566 211.116 183.200 1.00 13.29  ? 86  ASP C C     1 
ATOM   4242  O  O     . ASP C 1 86  ? 182.629 211.540 182.753 1.00 13.51  ? 86  ASP C O     1 
ATOM   4243  C  CB    . ASP C 1 86  ? 179.669 212.637 182.724 1.00 16.28  ? 86  ASP C CB    1 
ATOM   4244  C  CG    . ASP C 1 86  ? 178.380 212.911 181.967 1.00 18.22  ? 86  ASP C CG    1 
ATOM   4245  O  OD1   . ASP C 1 86  ? 178.432 213.007 180.732 1.00 20.04  ? 86  ASP C OD1   1 
ATOM   4246  O  OD2   . ASP C 1 86  ? 177.316 212.955 182.614 1.00 19.21  ? 86  ASP C OD2   1 
ATOM   4247  N  N     . VAL C 1 87  ? 181.458 210.538 184.403 1.00 12.29  ? 87  VAL C N     1 
ATOM   4248  C  CA    . VAL C 1 87  ? 182.585 210.430 185.307 1.00 11.63  ? 87  VAL C CA    1 
ATOM   4249  C  C     . VAL C 1 87  ? 182.622 209.005 185.848 1.00 10.60  ? 87  VAL C C     1 
ATOM   4250  O  O     . VAL C 1 87  ? 181.588 208.437 186.205 1.00 11.22  ? 87  VAL C O     1 
ATOM   4251  C  CB    . VAL C 1 87  ? 182.485 211.457 186.452 1.00 12.00  ? 87  VAL C CB    1 
ATOM   4252  C  CG1   . VAL C 1 87  ? 183.613 211.288 187.465 1.00 12.32  ? 87  VAL C CG1   1 
ATOM   4253  C  CG2   . VAL C 1 87  ? 182.443 212.883 185.920 1.00 12.02  ? 87  VAL C CG2   1 
ATOM   4254  N  N     . ALA C 1 88  ? 183.831 208.441 185.925 1.00 9.86   ? 88  ALA C N     1 
ATOM   4255  C  CA    . ALA C 1 88  ? 184.051 207.191 186.631 1.00 9.72   ? 88  ALA C CA    1 
ATOM   4256  C  C     . ALA C 1 88  ? 185.096 207.439 187.713 1.00 9.73   ? 88  ALA C C     1 
ATOM   4257  O  O     . ALA C 1 88  ? 186.173 207.962 187.421 1.00 9.95   ? 88  ALA C O     1 
ATOM   4258  C  CB    . ALA C 1 88  ? 184.496 206.098 185.674 1.00 9.83   ? 88  ALA C CB    1 
ATOM   4259  N  N     . VAL C 1 89  ? 184.768 207.056 188.945 1.00 9.73   ? 89  VAL C N     1 
ATOM   4260  C  CA    . VAL C 1 89  ? 185.692 207.130 190.058 1.00 9.70   ? 89  VAL C CA    1 
ATOM   4261  C  C     . VAL C 1 89  ? 185.916 205.726 190.603 1.00 10.07  ? 89  VAL C C     1 
ATOM   4262  O  O     . VAL C 1 89  ? 184.998 205.108 191.137 1.00 10.80  ? 89  VAL C O     1 
ATOM   4263  C  CB    . VAL C 1 89  ? 185.196 208.086 191.147 1.00 9.62   ? 89  VAL C CB    1 
ATOM   4264  C  CG1   . VAL C 1 89  ? 186.275 208.306 192.191 1.00 9.52   ? 89  VAL C CG1   1 
ATOM   4265  C  CG2   . VAL C 1 89  ? 184.740 209.412 190.561 1.00 9.32   ? 89  VAL C CG2   1 
ATOM   4266  N  N     . ASN C 1 90  ? 187.150 205.230 190.462 1.00 10.44  ? 90  ASN C N     1 
ATOM   4267  C  CA    . ASN C 1 90  ? 187.518 203.915 190.945 1.00 10.96  ? 90  ASN C CA    1 
ATOM   4268  C  C     . ASN C 1 90  ? 188.023 204.026 192.378 1.00 11.87  ? 90  ASN C C     1 
ATOM   4269  O  O     . ASN C 1 90  ? 189.145 204.463 192.604 1.00 13.13  ? 90  ASN C O     1 
ATOM   4270  C  CB    . ASN C 1 90  ? 188.580 203.275 190.061 1.00 11.44  ? 90  ASN C CB    1 
ATOM   4271  C  CG    . ASN C 1 90  ? 188.024 202.830 188.729 1.00 12.78  ? 90  ASN C CG    1 
ATOM   4272  O  OD1   . ASN C 1 90  ? 187.224 201.884 188.671 1.00 14.39  ? 90  ASN C OD1   1 
ATOM   4273  N  ND2   . ASN C 1 90  ? 188.420 203.497 187.654 1.00 13.14  ? 90  ASN C ND2   1 
ATOM   4274  N  N     . CYS C 1 91  ? 187.190 203.632 193.342 1.00 12.88  ? 91  CYS C N     1 
ATOM   4275  C  CA    . CYS C 1 91  ? 187.571 203.660 194.746 1.00 14.88  ? 91  CYS C CA    1 
ATOM   4276  C  C     . CYS C 1 91  ? 187.480 202.282 195.406 1.00 15.71  ? 91  CYS C C     1 
ATOM   4277  O  O     . CYS C 1 91  ? 187.715 202.164 196.607 1.00 18.14  ? 91  CYS C O     1 
ATOM   4278  C  CB    . CYS C 1 91  ? 186.701 204.626 195.548 1.00 15.34  ? 91  CYS C CB    1 
ATOM   4279  S  SG    . CYS C 1 91  ? 186.901 206.364 195.074 1.00 18.45  ? 91  CYS C SG    1 
ATOM   4280  N  N     . ALA C 1 92  ? 187.089 201.243 194.669 1.00 15.49  ? 92  ALA C N     1 
ATOM   4281  C  CA    . ALA C 1 92  ? 187.054 199.908 195.241 1.00 15.98  ? 92  ALA C CA    1 
ATOM   4282  C  C     . ALA C 1 92  ? 188.470 199.391 195.415 1.00 16.47  ? 92  ALA C C     1 
ATOM   4283  O  O     . ALA C 1 92  ? 189.338 199.590 194.568 1.00 18.64  ? 92  ALA C O     1 
ATOM   4284  C  CB    . ALA C 1 92  ? 186.250 198.961 194.391 1.00 15.64  ? 92  ALA C CB    1 
ATOM   4285  N  N     . GLY C 1 93  ? 188.690 198.682 196.510 1.00 17.41  ? 93  GLY C N     1 
ATOM   4286  C  CA    . GLY C 1 93  ? 190.001 198.125 196.750 1.00 17.86  ? 93  GLY C CA    1 
ATOM   4287  C  C     . GLY C 1 93  ? 190.042 197.367 198.064 1.00 18.47  ? 93  GLY C C     1 
ATOM   4288  O  O     . GLY C 1 93  ? 189.178 197.547 198.927 1.00 20.42  ? 93  GLY C O     1 
ATOM   4289  N  N     . ILE C 1 94  ? 191.050 196.500 198.173 1.00 16.91  ? 94  ILE C N     1 
ATOM   4290  C  CA    . ILE C 1 94  ? 191.319 195.801 199.413 1.00 17.78  ? 94  ILE C CA    1 
ATOM   4291  C  C     . ILE C 1 94  ? 192.788 196.006 199.751 1.00 18.62  ? 94  ILE C C     1 
ATOM   4292  O  O     . ILE C 1 94  ? 193.604 196.277 198.878 1.00 18.50  ? 94  ILE C O     1 
ATOM   4293  C  CB    . ILE C 1 94  ? 190.953 194.310 199.324 1.00 17.45  ? 94  ILE C CB    1 
ATOM   4294  C  CG1   . ILE C 1 94  ? 191.763 193.610 198.235 1.00 18.18  ? 94  ILE C CG1   1 
ATOM   4295  C  CG2   . ILE C 1 94  ? 189.452 194.141 199.109 1.00 18.03  ? 94  ILE C CG2   1 
ATOM   4296  C  CD1   . ILE C 1 94  ? 191.539 192.103 198.174 1.00 19.24  ? 94  ILE C CD1   1 
ATOM   4297  N  N     . ALA C 1 95  ? 193.094 195.828 201.033 1.00 20.24  ? 95  ALA C N     1 
ATOM   4298  C  CA    . ALA C 1 95  ? 194.462 195.868 201.516 1.00 22.20  ? 95  ALA C CA    1 
ATOM   4299  C  C     . ALA C 1 95  ? 194.750 194.603 202.309 1.00 23.55  ? 95  ALA C C     1 
ATOM   4300  O  O     . ALA C 1 95  ? 193.910 194.187 203.101 1.00 27.06  ? 95  ALA C O     1 
ATOM   4301  C  CB    . ALA C 1 95  ? 194.674 197.108 202.345 1.00 23.18  ? 95  ALA C CB    1 
ATOM   4302  N  N     . VAL C 1 96  ? 195.923 194.008 202.052 1.00 21.97  ? 96  VAL C N     1 
ATOM   4303  C  CA    . VAL C 1 96  ? 196.443 192.967 202.906 1.00 22.15  ? 96  VAL C CA    1 
ATOM   4304  C  C     . VAL C 1 96  ? 197.809 193.416 203.404 1.00 19.56  ? 96  VAL C C     1 
ATOM   4305  O  O     . VAL C 1 96  ? 198.501 194.188 202.752 1.00 20.17  ? 96  VAL C O     1 
ATOM   4306  C  CB    . VAL C 1 96  ? 196.542 191.609 202.198 1.00 25.98  ? 96  VAL C CB    1 
ATOM   4307  C  CG1   . VAL C 1 96  ? 195.237 191.209 201.535 1.00 29.01  ? 96  VAL C CG1   1 
ATOM   4308  C  CG2   . VAL C 1 96  ? 197.683 191.568 201.199 1.00 26.96  ? 96  VAL C CG2   1 
ATOM   4309  N  N     . ALA C 1 97  ? 198.159 192.949 204.599 1.00 18.36  ? 97  ALA C N     1 
ATOM   4310  C  CA    . ALA C 1 97  ? 199.475 193.134 205.163 1.00 17.00  ? 97  ALA C CA    1 
ATOM   4311  C  C     . ALA C 1 97  ? 200.081 191.746 205.322 1.00 16.17  ? 97  ALA C C     1 
ATOM   4312  O  O     . ALA C 1 97  ? 199.627 190.954 206.147 1.00 17.24  ? 97  ALA C O     1 
ATOM   4313  C  CB    . ALA C 1 97  ? 199.376 193.872 206.487 1.00 16.79  ? 97  ALA C CB    1 
ATOM   4314  N  N     . SER C 1 98  ? 201.149 191.476 204.570 1.00 15.50  ? 98  SER C N     1 
ATOM   4315  C  CA    . SER C 1 98  ? 201.865 190.215 204.684 1.00 15.27  ? 98  SER C CA    1 
ATOM   4316  C  C     . SER C 1 98  ? 203.300 190.410 204.216 1.00 14.54  ? 98  SER C C     1 
ATOM   4317  O  O     . SER C 1 98  ? 203.517 190.962 203.141 1.00 14.42  ? 98  SER C O     1 
ATOM   4318  C  CB    . SER C 1 98  ? 201.160 189.156 203.862 1.00 15.72  ? 98  SER C CB    1 
ATOM   4319  O  OG    . SER C 1 98  ? 201.756 187.884 204.045 1.00 15.54  ? 98  SER C OG    1 
ATOM   4320  N  N     . LYS C 1 99  ? 204.274 189.977 205.014 1.00 15.20  ? 99  LYS C N     1 
ATOM   4321  C  CA    . LYS C 1 99  ? 205.666 190.069 204.600 1.00 16.38  ? 99  LYS C CA    1 
ATOM   4322  C  C     . LYS C 1 99  ? 205.941 189.113 203.439 1.00 14.75  ? 99  LYS C C     1 
ATOM   4323  O  O     . LYS C 1 99  ? 205.326 188.057 203.338 1.00 14.78  ? 99  LYS C O     1 
ATOM   4324  C  CB    . LYS C 1 99  ? 206.621 189.747 205.751 1.00 19.17  ? 99  LYS C CB    1 
ATOM   4325  C  CG    . LYS C 1 99  ? 206.608 190.773 206.862 1.00 22.33  ? 99  LYS C CG    1 
ATOM   4326  C  CD    . LYS C 1 99  ? 207.598 190.417 207.960 1.00 25.97  ? 99  LYS C CD    1 
ATOM   4327  C  CE    . LYS C 1 99  ? 207.409 191.219 209.203 1.00 29.08  ? 99  LYS C CE    1 
ATOM   4328  N  NZ    . LYS C 1 99  ? 207.983 190.518 210.355 1.00 31.88  ? 99  LYS C NZ    1 
ATOM   4329  N  N     . THR C 1 100 ? 206.863 189.507 202.556 1.00 14.36  ? 100 THR C N     1 
ATOM   4330  C  CA    . THR C 1 100 ? 207.261 188.660 201.442 1.00 14.63  ? 100 THR C CA    1 
ATOM   4331  C  C     . THR C 1 100 ? 207.798 187.332 201.985 1.00 14.20  ? 100 THR C C     1 
ATOM   4332  O  O     . THR C 1 100 ? 207.436 186.265 201.501 1.00 14.32  ? 100 THR C O     1 
ATOM   4333  C  CB    . THR C 1 100 ? 208.304 189.370 200.579 1.00 14.47  ? 100 THR C CB    1 
ATOM   4334  O  OG1   . THR C 1 100 ? 207.692 190.553 200.052 1.00 15.07  ? 100 THR C OG1   1 
ATOM   4335  C  CG2   . THR C 1 100 ? 208.798 188.479 199.450 1.00 14.40  ? 100 THR C CG2   1 
ATOM   4336  N  N     . TYR C 1 101 ? 208.687 187.416 202.971 1.00 15.24  ? 101 TYR C N     1 
ATOM   4337  C  CA    . TYR C 1 101 ? 209.259 186.242 203.597 1.00 15.86  ? 101 TYR C CA    1 
ATOM   4338  C  C     . TYR C 1 101 ? 209.715 186.610 204.998 1.00 18.08  ? 101 TYR C C     1 
ATOM   4339  O  O     . TYR C 1 101 ? 210.293 187.673 205.204 1.00 19.59  ? 101 TYR C O     1 
ATOM   4340  C  CB    . TYR C 1 101 ? 210.418 185.676 202.778 1.00 16.83  ? 101 TYR C CB    1 
ATOM   4341  C  CG    . TYR C 1 101 ? 211.032 184.440 203.407 1.00 17.70  ? 101 TYR C CG    1 
ATOM   4342  C  CD1   . TYR C 1 101 ? 210.327 183.240 203.432 1.00 18.32  ? 101 TYR C CD1   1 
ATOM   4343  C  CD2   . TYR C 1 101 ? 212.294 184.475 203.987 1.00 18.20  ? 101 TYR C CD2   1 
ATOM   4344  C  CE1   . TYR C 1 101 ? 210.866 182.111 204.023 1.00 19.12  ? 101 TYR C CE1   1 
ATOM   4345  C  CE2   . TYR C 1 101 ? 212.843 183.350 204.576 1.00 18.76  ? 101 TYR C CE2   1 
ATOM   4346  C  CZ    . TYR C 1 101 ? 212.121 182.170 204.602 1.00 19.56  ? 101 TYR C CZ    1 
ATOM   4347  O  OH    . TYR C 1 101 ? 212.670 181.056 205.167 1.00 20.28  ? 101 TYR C OH    1 
ATOM   4348  N  N     . ASN C 1 102 ? 209.429 185.725 205.954 1.00 18.94  ? 102 ASN C N     1 
ATOM   4349  C  CA    . ASN C 1 102 ? 209.817 185.908 207.339 1.00 21.38  ? 102 ASN C CA    1 
ATOM   4350  C  C     . ASN C 1 102 ? 210.769 184.769 207.709 1.00 21.34  ? 102 ASN C C     1 
ATOM   4351  O  O     . ASN C 1 102 ? 210.350 183.616 207.820 1.00 21.71  ? 102 ASN C O     1 
ATOM   4352  C  CB    . ASN C 1 102 ? 208.589 185.926 208.248 1.00 23.53  ? 102 ASN C CB    1 
ATOM   4353  C  CG    . ASN C 1 102 ? 208.890 186.402 209.650 1.00 25.73  ? 102 ASN C CG    1 
ATOM   4354  O  OD1   . ASN C 1 102 ? 210.001 186.226 210.157 1.00 27.96  ? 102 ASN C OD1   1 
ATOM   4355  N  ND2   . ASN C 1 102 ? 207.932 187.057 210.279 1.00 28.14  ? 102 ASN C ND2   1 
ATOM   4356  N  N     . LEU C 1 103 ? 212.053 185.088 207.865 1.00 22.23  ? 103 LEU C N     1 
ATOM   4357  C  CA    . LEU C 1 103 ? 213.072 184.081 208.110 1.00 25.23  ? 103 LEU C CA    1 
ATOM   4358  C  C     . LEU C 1 103 ? 212.865 183.401 209.462 1.00 27.42  ? 103 LEU C C     1 
ATOM   4359  O  O     . LEU C 1 103 ? 212.985 182.182 209.561 1.00 29.72  ? 103 LEU C O     1 
ATOM   4360  C  CB    . LEU C 1 103 ? 214.468 184.697 208.016 1.00 25.93  ? 103 LEU C CB    1 
ATOM   4361  C  CG    . LEU C 1 103 ? 215.640 183.760 208.334 1.00 27.33  ? 103 LEU C CG    1 
ATOM   4362  C  CD1   . LEU C 1 103 ? 215.653 182.554 207.421 1.00 28.12  ? 103 LEU C CD1   1 
ATOM   4363  C  CD2   . LEU C 1 103 ? 216.963 184.494 208.247 1.00 27.90  ? 103 LEU C CD2   1 
ATOM   4364  N  N     . LYS C 1 104 ? 212.568 184.182 210.503 1.00 31.70  ? 104 LYS C N     1 
ATOM   4365  C  CA    . LYS C 1 104 ? 212.439 183.631 211.845 1.00 37.08  ? 104 LYS C CA    1 
ATOM   4366  C  C     . LYS C 1 104 ? 211.265 182.657 211.914 1.00 35.83  ? 104 LYS C C     1 
ATOM   4367  O  O     . LYS C 1 104 ? 211.395 181.536 212.415 1.00 37.55  ? 104 LYS C O     1 
ATOM   4368  C  CB    . LYS C 1 104 ? 212.247 184.753 212.867 1.00 44.30  ? 104 LYS C CB    1 
ATOM   4369  C  CG    . LYS C 1 104 ? 212.189 184.284 214.309 1.00 51.54  ? 104 LYS C CG    1 
ATOM   4370  C  CD    . LYS C 1 104 ? 211.099 184.957 215.133 1.00 58.47  ? 104 LYS C CD    1 
ATOM   4371  C  CE    . LYS C 1 104 ? 211.360 186.409 215.409 1.00 63.69  ? 104 LYS C CE    1 
ATOM   4372  N  NZ    . LYS C 1 104 ? 210.242 187.017 216.141 1.00 65.80  ? 104 LYS C NZ    1 
ATOM   4373  N  N     . LYS C 1 105 ? 210.115 183.060 211.368 1.00 36.34  ? 105 LYS C N     1 
ATOM   4374  C  CA    . LYS C 1 105 ? 208.939 182.204 211.376 1.00 36.52  ? 105 LYS C CA    1 
ATOM   4375  C  C     . LYS C 1 105 ? 208.962 181.176 210.247 1.00 32.81  ? 105 LYS C C     1 
ATOM   4376  O  O     . LYS C 1 105 ? 208.180 180.237 210.269 1.00 33.87  ? 105 LYS C O     1 
ATOM   4377  C  CB    . LYS C 1 105 ? 207.655 183.025 211.277 1.00 40.85  ? 105 LYS C CB    1 
ATOM   4378  C  CG    . LYS C 1 105 ? 207.325 183.826 212.514 1.00 49.34  ? 105 LYS C CG    1 
ATOM   4379  C  CD    . LYS C 1 105 ? 205.819 184.035 212.704 1.00 54.55  ? 105 LYS C CD    1 
ATOM   4380  C  CE    . LYS C 1 105 ? 205.249 185.141 211.879 1.00 57.58  ? 105 LYS C CE    1 
ATOM   4381  N  NZ    . LYS C 1 105 ? 203.820 184.960 211.591 1.00 59.77  ? 105 LYS C NZ    1 
ATOM   4382  N  N     . GLY C 1 106 ? 209.852 181.341 209.265 1.00 29.95  ? 106 GLY C N     1 
ATOM   4383  C  CA    . GLY C 1 106 ? 209.848 180.475 208.099 1.00 26.86  ? 106 GLY C CA    1 
ATOM   4384  C  C     . GLY C 1 106 ? 208.547 180.597 207.307 1.00 26.57  ? 106 GLY C C     1 
ATOM   4385  O  O     . GLY C 1 106 ? 208.082 179.614 206.740 1.00 29.22  ? 106 GLY C O     1 
ATOM   4386  N  N     . GLN C 1 107 ? 207.980 181.811 207.257 1.00 24.02  ? 107 GLN C N     1 
ATOM   4387  C  CA    . GLN C 1 107 ? 206.693 182.039 206.620 1.00 24.96  ? 107 GLN C CA    1 
ATOM   4388  C  C     . GLN C 1 107 ? 206.903 182.799 205.316 1.00 20.85  ? 107 GLN C C     1 
ATOM   4389  O  O     . GLN C 1 107 ? 207.636 183.783 205.270 1.00 21.51  ? 107 GLN C O     1 
ATOM   4390  C  CB    . GLN C 1 107 ? 205.781 182.825 207.559 1.00 28.71  ? 107 GLN C CB    1 
ATOM   4391  C  CG    . GLN C 1 107 ? 204.468 183.276 206.933 1.00 34.32  ? 107 GLN C CG    1 
ATOM   4392  C  CD    . GLN C 1 107 ? 203.552 183.957 207.928 1.00 41.18  ? 107 GLN C CD    1 
ATOM   4393  O  OE1   . GLN C 1 107 ? 203.742 183.875 209.148 1.00 44.49  ? 107 GLN C OE1   1 
ATOM   4394  N  NE2   . GLN C 1 107 ? 202.537 184.641 207.421 1.00 46.26  ? 107 GLN C NE2   1 
ATOM   4395  N  N     . THR C 1 108 ? 206.229 182.325 204.270 1.00 18.19  ? 108 THR C N     1 
ATOM   4396  C  CA    . THR C 1 108 ? 206.312 182.915 202.948 1.00 16.50  ? 108 THR C CA    1 
ATOM   4397  C  C     . THR C 1 108 ? 204.957 183.525 202.607 1.00 14.54  ? 108 THR C C     1 
ATOM   4398  O  O     . THR C 1 108 ? 203.910 182.954 202.891 1.00 14.69  ? 108 THR C O     1 
ATOM   4399  C  CB    . THR C 1 108 ? 206.719 181.875 201.910 1.00 16.55  ? 108 THR C CB    1 
ATOM   4400  O  OG1   . THR C 1 108 ? 207.964 181.300 202.298 1.00 16.79  ? 108 THR C OG1   1 
ATOM   4401  C  CG2   . THR C 1 108 ? 206.875 182.494 200.536 1.00 16.30  ? 108 THR C CG2   1 
ATOM   4402  N  N     . HIS C 1 109 ? 204.999 184.702 201.980 1.00 13.50  ? 109 HIS C N     1 
ATOM   4403  C  CA    . HIS C 1 109 ? 203.800 185.333 201.469 1.00 12.51  ? 109 HIS C CA    1 
ATOM   4404  C  C     . HIS C 1 109 ? 203.079 184.350 200.551 1.00 12.45  ? 109 HIS C C     1 
ATOM   4405  O  O     . HIS C 1 109 ? 203.666 183.758 199.650 1.00 12.47  ? 109 HIS C O     1 
ATOM   4406  C  CB    . HIS C 1 109 ? 204.173 186.606 200.707 1.00 12.32  ? 109 HIS C CB    1 
ATOM   4407  C  CG    . HIS C 1 109 ? 203.039 187.509 200.393 1.00 11.97  ? 109 HIS C CG    1 
ATOM   4408  N  ND1   . HIS C 1 109 ? 201.948 187.108 199.665 1.00 11.32  ? 109 HIS C ND1   1 
ATOM   4409  C  CD2   . HIS C 1 109 ? 202.855 188.815 200.661 1.00 12.05  ? 109 HIS C CD2   1 
ATOM   4410  C  CE1   . HIS C 1 109 ? 201.120 188.132 199.531 1.00 12.15  ? 109 HIS C CE1   1 
ATOM   4411  N  NE2   . HIS C 1 109 ? 201.656 189.184 200.119 1.00 11.92  ? 109 HIS C NE2   1 
ATOM   4412  N  N     . THR C 1 110 ? 201.775 184.222 200.753 1.00 13.15  ? 110 THR C N     1 
ATOM   4413  C  CA    . THR C 1 110 ? 200.963 183.349 199.926 1.00 14.64  ? 110 THR C CA    1 
ATOM   4414  C  C     . THR C 1 110 ? 200.800 183.959 198.531 1.00 14.57  ? 110 THR C C     1 
ATOM   4415  O  O     . THR C 1 110 ? 200.598 185.169 198.387 1.00 14.06  ? 110 THR C O     1 
ATOM   4416  C  CB    . THR C 1 110 ? 199.609 183.187 200.624 1.00 16.89  ? 110 THR C CB    1 
ATOM   4417  O  OG1   . THR C 1 110 ? 199.824 182.343 201.758 1.00 16.71  ? 110 THR C OG1   1 
ATOM   4418  C  CG2   . THR C 1 110 ? 198.665 182.354 199.813 1.00 19.82  ? 110 THR C CG2   1 
ATOM   4419  N  N     . LEU C 1 111 ? 200.831 183.112 197.511 1.00 14.11  ? 111 LEU C N     1 
ATOM   4420  C  CA    . LEU C 1 111 ? 200.574 183.553 196.149 1.00 15.34  ? 111 LEU C CA    1 
ATOM   4421  C  C     . LEU C 1 111 ? 199.122 184.014 195.993 1.00 16.96  ? 111 LEU C C     1 
ATOM   4422  O  O     . LEU C 1 111 ? 198.845 184.982 195.284 1.00 17.22  ? 111 LEU C O     1 
ATOM   4423  C  CB    . LEU C 1 111 ? 200.920 182.462 195.141 1.00 15.89  ? 111 LEU C CB    1 
ATOM   4424  C  CG    . LEU C 1 111 ? 200.931 182.898 193.672 1.00 16.51  ? 111 LEU C CG    1 
ATOM   4425  C  CD1   . LEU C 1 111 ? 201.881 184.079 193.472 1.00 16.66  ? 111 LEU C CD1   1 
ATOM   4426  C  CD2   . LEU C 1 111 ? 201.310 181.748 192.757 1.00 16.80  ? 111 LEU C CD2   1 
ATOM   4427  N  N     . GLU C 1 112 ? 198.194 183.324 196.657 1.00 18.57  ? 112 GLU C N     1 
ATOM   4428  C  CA    . GLU C 1 112 ? 196.783 183.663 196.568 1.00 20.22  ? 112 GLU C CA    1 
ATOM   4429  C  C     . GLU C 1 112 ? 196.507 185.043 197.178 1.00 18.25  ? 112 GLU C C     1 
ATOM   4430  O  O     . GLU C 1 112 ? 195.666 185.791 196.670 1.00 17.86  ? 112 GLU C O     1 
ATOM   4431  C  CB    . GLU C 1 112 ? 195.904 182.593 197.214 1.00 24.84  ? 112 GLU C CB    1 
ATOM   4432  C  CG    . GLU C 1 112 ? 195.867 181.291 196.420 1.00 31.12  ? 112 GLU C CG    1 
ATOM   4433  C  CD    . GLU C 1 112 ? 197.083 180.385 196.536 1.00 39.23  ? 112 GLU C CD    1 
ATOM   4434  O  OE1   . GLU C 1 112 ? 197.976 180.656 197.371 1.00 35.18  ? 112 GLU C OE1   1 
ATOM   4435  O  OE2   . GLU C 1 112 ? 197.116 179.385 195.780 1.00 44.24  ? 112 GLU C OE2   1 
ATOM   4436  N  N     . ASP C 1 113 ? 197.199 185.378 198.274 1.00 17.48  ? 113 ASP C N     1 
ATOM   4437  C  CA    . ASP C 1 113 ? 197.055 186.697 198.867 1.00 18.41  ? 113 ASP C CA    1 
ATOM   4438  C  C     . ASP C 1 113 ? 197.485 187.785 197.883 1.00 16.34  ? 113 ASP C C     1 
ATOM   4439  O  O     . ASP C 1 113 ? 196.818 188.813 197.748 1.00 17.61  ? 113 ASP C O     1 
ATOM   4440  C  CB    . ASP C 1 113 ? 197.833 186.809 200.161 1.00 19.96  ? 113 ASP C CB    1 
ATOM   4441  C  CG    . ASP C 1 113 ? 197.044 186.405 201.394 1.00 23.69  ? 113 ASP C CG    1 
ATOM   4442  O  OD1   . ASP C 1 113 ? 195.805 186.257 201.275 1.00 26.20  ? 113 ASP C OD1   1 
ATOM   4443  O  OD2   . ASP C 1 113 ? 197.669 186.265 202.466 1.00 27.04  ? 113 ASP C OD2   1 
ATOM   4444  N  N     . PHE C 1 114 ? 198.609 187.562 197.205 1.00 14.19  ? 114 PHE C N     1 
ATOM   4445  C  CA    . PHE C 1 114 ? 199.078 188.503 196.205 1.00 13.75  ? 114 PHE C CA    1 
ATOM   4446  C  C     . PHE C 1 114 ? 198.077 188.621 195.060 1.00 13.87  ? 114 PHE C C     1 
ATOM   4447  O  O     . PHE C 1 114 ? 197.794 189.727 194.595 1.00 13.42  ? 114 PHE C O     1 
ATOM   4448  C  CB    . PHE C 1 114 ? 200.455 188.080 195.703 1.00 12.87  ? 114 PHE C CB    1 
ATOM   4449  C  CG    . PHE C 1 114 ? 201.138 189.133 194.859 1.00 11.59  ? 114 PHE C CG    1 
ATOM   4450  C  CD1   . PHE C 1 114 ? 201.882 190.136 195.465 1.00 11.28  ? 114 PHE C CD1   1 
ATOM   4451  C  CD2   . PHE C 1 114 ? 201.060 189.092 193.477 1.00 11.17  ? 114 PHE C CD2   1 
ATOM   4452  C  CE1   . PHE C 1 114 ? 202.544 191.085 194.706 1.00 10.87  ? 114 PHE C CE1   1 
ATOM   4453  C  CE2   . PHE C 1 114 ? 201.708 190.054 192.720 1.00 11.05  ? 114 PHE C CE2   1 
ATOM   4454  C  CZ    . PHE C 1 114 ? 202.456 191.037 193.337 1.00 10.61  ? 114 PHE C CZ    1 
ATOM   4455  N  N     . GLN C 1 115 ? 197.556 187.480 194.601 1.00 14.70  ? 115 GLN C N     1 
ATOM   4456  C  CA    . GLN C 1 115 ? 196.676 187.453 193.444 1.00 17.08  ? 115 GLN C CA    1 
ATOM   4457  C  C     . GLN C 1 115 ? 195.369 188.194 193.737 1.00 15.87  ? 115 GLN C C     1 
ATOM   4458  O  O     . GLN C 1 115 ? 194.891 188.954 192.899 1.00 15.81  ? 115 GLN C O     1 
ATOM   4459  C  CB    . GLN C 1 115 ? 196.375 186.013 193.042 1.00 19.59  ? 115 GLN C CB    1 
ATOM   4460  C  CG    . GLN C 1 115 ? 195.559 185.882 191.764 1.00 23.16  ? 115 GLN C CG    1 
ATOM   4461  C  CD    . GLN C 1 115 ? 196.310 186.349 190.538 1.00 27.35  ? 115 GLN C CD    1 
ATOM   4462  O  OE1   . GLN C 1 115 ? 197.341 185.787 190.148 1.00 31.21  ? 115 GLN C OE1   1 
ATOM   4463  N  NE2   . GLN C 1 115 ? 195.793 187.384 189.896 1.00 29.90  ? 115 GLN C NE2   1 
ATOM   4464  N  N     . ARG C 1 116 ? 194.790 187.982 194.922 1.00 15.66  ? 116 ARG C N     1 
ATOM   4465  C  CA    . ARG C 1 116 ? 193.482 188.553 195.196 1.00 15.88  ? 116 ARG C CA    1 
ATOM   4466  C  C     . ARG C 1 116 ? 193.564 190.073 195.322 1.00 14.74  ? 116 ARG C C     1 
ATOM   4467  O  O     . ARG C 1 116 ? 192.617 190.775 194.979 1.00 15.02  ? 116 ARG C O     1 
ATOM   4468  C  CB    . ARG C 1 116 ? 192.849 187.903 196.422 1.00 17.94  ? 116 ARG C CB    1 
ATOM   4469  C  CG    . ARG C 1 116 ? 193.556 188.167 197.730 1.00 20.52  ? 116 ARG C CG    1 
ATOM   4470  C  CD    . ARG C 1 116 ? 193.036 187.178 198.805 1.00 22.62  ? 116 ARG C CD    1 
ATOM   4471  N  NE    . ARG C 1 116 ? 193.519 187.471 200.159 1.00 22.56  ? 116 ARG C NE    1 
ATOM   4472  C  CZ    . ARG C 1 116 ? 192.977 188.358 200.996 1.00 24.41  ? 116 ARG C CZ    1 
ATOM   4473  N  NH1   . ARG C 1 116 ? 191.903 189.068 200.661 1.00 23.43  ? 116 ARG C NH1   1 
ATOM   4474  N  NH2   . ARG C 1 116 ? 193.532 188.532 202.181 1.00 27.03  ? 116 ARG C NH2   1 
ATOM   4475  N  N     . VAL C 1 117 ? 194.676 190.600 195.830 1.00 14.04  ? 117 VAL C N     1 
ATOM   4476  C  CA    . VAL C 1 117 ? 194.858 192.043 195.888 1.00 14.08  ? 117 VAL C CA    1 
ATOM   4477  C  C     . VAL C 1 117 ? 194.959 192.627 194.480 1.00 13.38  ? 117 VAL C C     1 
ATOM   4478  O  O     . VAL C 1 117 ? 194.342 193.652 194.189 1.00 14.18  ? 117 VAL C O     1 
ATOM   4479  C  CB    . VAL C 1 117 ? 196.072 192.411 196.747 1.00 13.99  ? 117 VAL C CB    1 
ATOM   4480  C  CG1   . VAL C 1 117 ? 196.342 193.906 196.689 1.00 14.52  ? 117 VAL C CG1   1 
ATOM   4481  C  CG2   . VAL C 1 117 ? 195.866 191.974 198.179 1.00 14.71  ? 117 VAL C CG2   1 
ATOM   4482  N  N     . LEU C 1 118 ? 195.728 191.980 193.604 1.00 14.75  ? 118 LEU C N     1 
ATOM   4483  C  CA    . LEU C 1 118 ? 195.850 192.440 192.226 1.00 15.49  ? 118 LEU C CA    1 
ATOM   4484  C  C     . LEU C 1 118 ? 194.498 192.419 191.518 1.00 15.15  ? 118 LEU C C     1 
ATOM   4485  O  O     . LEU C 1 118 ? 194.174 193.352 190.774 1.00 15.83  ? 118 LEU C O     1 
ATOM   4486  C  CB    . LEU C 1 118 ? 196.836 191.594 191.423 1.00 16.52  ? 118 LEU C CB    1 
ATOM   4487  C  CG    . LEU C 1 118 ? 198.313 191.707 191.771 1.00 18.99  ? 118 LEU C CG    1 
ATOM   4488  C  CD1   . LEU C 1 118 ? 199.051 190.834 190.749 1.00 20.50  ? 118 LEU C CD1   1 
ATOM   4489  C  CD2   . LEU C 1 118 ? 198.818 193.131 191.781 1.00 18.71  ? 118 LEU C CD2   1 
ATOM   4490  N  N     . ASP C 1 119 ? 193.724 191.342 191.722 1.00 16.46  ? 119 ASP C N     1 
ATOM   4491  C  CA    . ASP C 1 119 ? 192.455 191.182 191.030 1.00 18.11  ? 119 ASP C CA    1 
ATOM   4492  C  C     . ASP C 1 119 ? 191.511 192.345 191.327 1.00 15.66  ? 119 ASP C C     1 
ATOM   4493  O  O     . ASP C 1 119 ? 190.900 192.903 190.416 1.00 16.17  ? 119 ASP C O     1 
ATOM   4494  C  CB    . ASP C 1 119 ? 191.788 189.866 191.395 1.00 21.11  ? 119 ASP C CB    1 
ATOM   4495  C  CG    . ASP C 1 119 ? 192.554 188.646 190.925 1.00 27.07  ? 119 ASP C CG    1 
ATOM   4496  O  OD1   . ASP C 1 119 ? 193.184 188.775 189.853 1.00 30.08  ? 119 ASP C OD1   1 
ATOM   4497  O  OD2   . ASP C 1 119 ? 192.543 187.621 191.663 1.00 32.76  ? 119 ASP C OD2   1 
ATOM   4498  N  N     . VAL C 1 120 ? 191.389 192.709 192.602 1.00 15.23  ? 120 VAL C N     1 
ATOM   4499  C  CA    . VAL C 1 120 ? 190.444 193.739 192.981 1.00 15.73  ? 120 VAL C CA    1 
ATOM   4500  C  C     . VAL C 1 120 ? 191.021 195.121 192.673 1.00 13.95  ? 120 VAL C C     1 
ATOM   4501  O  O     . VAL C 1 120 ? 190.385 195.929 192.002 1.00 14.97  ? 120 VAL C O     1 
ATOM   4502  C  CB    . VAL C 1 120 ? 190.055 193.613 194.464 1.00 18.10  ? 120 VAL C CB    1 
ATOM   4503  C  CG1   . VAL C 1 120 ? 189.120 194.743 194.863 1.00 18.59  ? 120 VAL C CG1   1 
ATOM   4504  C  CG2   . VAL C 1 120 ? 189.405 192.268 194.752 1.00 20.50  ? 120 VAL C CG2   1 
ATOM   4505  N  N     . ASN C 1 121 ? 192.228 195.401 193.170 1.00 12.61  ? 121 ASN C N     1 
ATOM   4506  C  CA    . ASN C 1 121 ? 192.782 196.743 193.099 1.00 12.26  ? 121 ASN C CA    1 
ATOM   4507  C  C     . ASN C 1 121 ? 193.146 197.115 191.666 1.00 12.65  ? 121 ASN C C     1 
ATOM   4508  O  O     . ASN C 1 121 ? 192.796 198.188 191.189 1.00 14.47  ? 121 ASN C O     1 
ATOM   4509  C  CB    . ASN C 1 121 ? 193.981 196.889 194.025 1.00 11.74  ? 121 ASN C CB    1 
ATOM   4510  C  CG    . ASN C 1 121 ? 193.607 196.753 195.480 1.00 11.38  ? 121 ASN C CG    1 
ATOM   4511  O  OD1   . ASN C 1 121 ? 192.464 196.426 195.798 1.00 12.39  ? 121 ASN C OD1   1 
ATOM   4512  N  ND2   . ASN C 1 121 ? 194.558 196.952 196.380 1.00 11.25  ? 121 ASN C ND2   1 
ATOM   4513  N  N     . LEU C 1 122 ? 193.871 196.224 190.980 1.00 12.56  ? 122 LEU C N     1 
ATOM   4514  C  CA    . LEU C 1 122 ? 194.484 196.557 189.705 1.00 12.10  ? 122 LEU C CA    1 
ATOM   4515  C  C     . LEU C 1 122 ? 193.628 196.055 188.553 1.00 12.55  ? 122 LEU C C     1 
ATOM   4516  O  O     . LEU C 1 122 ? 193.220 196.834 187.693 1.00 12.54  ? 122 LEU C O     1 
ATOM   4517  C  CB    . LEU C 1 122 ? 195.904 195.984 189.624 1.00 11.80  ? 122 LEU C CB    1 
ATOM   4518  C  CG    . LEU C 1 122 ? 196.681 196.289 188.342 1.00 11.65  ? 122 LEU C CG    1 
ATOM   4519  C  CD1   . LEU C 1 122 ? 196.615 197.762 187.971 1.00 11.82  ? 122 LEU C CD1   1 
ATOM   4520  C  CD2   . LEU C 1 122 ? 198.122 195.834 188.490 1.00 11.93  ? 122 LEU C CD2   1 
ATOM   4521  N  N     . MET C 1 123 ? 193.356 194.751 188.537 1.00 13.41  ? 123 MET C N     1 
ATOM   4522  C  CA    . MET C 1 123 ? 192.551 194.173 187.474 1.00 15.78  ? 123 MET C CA    1 
ATOM   4523  C  C     . MET C 1 123 ? 191.127 194.743 187.518 1.00 14.27  ? 123 MET C C     1 
ATOM   4524  O  O     . MET C 1 123 ? 190.528 195.035 186.484 1.00 14.46  ? 123 MET C O     1 
ATOM   4525  C  CB    . MET C 1 123 ? 192.542 192.646 187.578 1.00 18.31  ? 123 MET C CB    1 
ATOM   4526  C  CG    . MET C 1 123 ? 191.991 191.965 186.354 1.00 24.04  ? 123 MET C CG    1 
ATOM   4527  S  SD    . MET C 1 123 ? 190.201 191.793 186.415 1.00 30.71  ? 123 MET C SD    1 
ATOM   4528  C  CE    . MET C 1 123 ? 189.927 190.609 187.735 1.00 29.89  ? 123 MET C CE    1 
ATOM   4529  N  N     . GLY C 1 124 ? 190.576 194.905 188.721 1.00 13.58  ? 124 GLY C N     1 
ATOM   4530  C  CA    . GLY C 1 124 ? 189.241 195.456 188.868 1.00 13.05  ? 124 GLY C CA    1 
ATOM   4531  C  C     . GLY C 1 124 ? 189.163 196.895 188.356 1.00 12.39  ? 124 GLY C C     1 
ATOM   4532  O  O     . GLY C 1 124 ? 188.198 197.285 187.705 1.00 13.10  ? 124 GLY C O     1 
ATOM   4533  N  N     . THR C 1 125 ? 190.189 197.699 188.651 1.00 11.62  ? 125 THR C N     1 
ATOM   4534  C  CA    . THR C 1 125 ? 190.223 199.072 188.175 1.00 11.10  ? 125 THR C CA    1 
ATOM   4535  C  C     . THR C 1 125 ? 190.253 199.105 186.644 1.00 10.37  ? 125 THR C C     1 
ATOM   4536  O  O     . THR C 1 125 ? 189.526 199.876 186.024 1.00 9.77   ? 125 THR C O     1 
ATOM   4537  C  CB    . THR C 1 125 ? 191.413 199.819 188.768 1.00 11.38  ? 125 THR C CB    1 
ATOM   4538  O  OG1   . THR C 1 125 ? 191.118 200.119 190.131 1.00 11.47  ? 125 THR C OG1   1 
ATOM   4539  C  CG2   . THR C 1 125 ? 191.700 201.107 188.018 1.00 10.83  ? 125 THR C CG2   1 
ATOM   4540  N  N     . PHE C 1 126 ? 191.110 198.288 186.031 1.00 10.36  ? 126 PHE C N     1 
ATOM   4541  C  CA    . PHE C 1 126 ? 191.207 198.265 184.580 1.00 11.01  ? 126 PHE C CA    1 
ATOM   4542  C  C     . PHE C 1 126 ? 189.898 197.766 183.962 1.00 11.08  ? 126 PHE C C     1 
ATOM   4543  O  O     . PHE C 1 126 ? 189.479 198.250 182.912 1.00 11.30  ? 126 PHE C O     1 
ATOM   4544  C  CB    . PHE C 1 126 ? 192.384 197.407 184.117 1.00 11.57  ? 126 PHE C CB    1 
ATOM   4545  C  CG    . PHE C 1 126 ? 192.547 197.432 182.609 1.00 12.11  ? 126 PHE C CG    1 
ATOM   4546  C  CD1   . PHE C 1 126 ? 193.067 198.548 181.965 1.00 12.46  ? 126 PHE C CD1   1 
ATOM   4547  C  CD2   . PHE C 1 126 ? 192.129 196.351 181.842 1.00 12.70  ? 126 PHE C CD2   1 
ATOM   4548  C  CE1   . PHE C 1 126 ? 193.163 198.576 180.587 1.00 13.44  ? 126 PHE C CE1   1 
ATOM   4549  C  CE2   . PHE C 1 126 ? 192.260 196.373 180.465 1.00 12.79  ? 126 PHE C CE2   1 
ATOM   4550  C  CZ    . PHE C 1 126 ? 192.762 197.485 179.837 1.00 12.97  ? 126 PHE C CZ    1 
ATOM   4551  N  N     . ASN C 1 127 ? 189.267 196.782 184.599 1.00 11.46  ? 127 ASN C N     1 
ATOM   4552  C  CA    . ASN C 1 127 ? 187.999 196.260 184.109 1.00 12.13  ? 127 ASN C CA    1 
ATOM   4553  C  C     . ASN C 1 127 ? 186.943 197.368 184.042 1.00 11.41  ? 127 ASN C C     1 
ATOM   4554  O  O     . ASN C 1 127 ? 186.196 197.469 183.073 1.00 12.75  ? 127 ASN C O     1 
ATOM   4555  C  CB    . ASN C 1 127 ? 187.525 195.099 184.974 1.00 12.98  ? 127 ASN C CB    1 
ATOM   4556  C  CG    . ASN C 1 127 ? 186.261 194.471 184.455 1.00 13.83  ? 127 ASN C CG    1 
ATOM   4557  O  OD1   . ASN C 1 127 ? 186.122 194.295 183.245 1.00 14.72  ? 127 ASN C OD1   1 
ATOM   4558  N  ND2   . ASN C 1 127 ? 185.334 194.158 185.346 1.00 14.56  ? 127 ASN C ND2   1 
ATOM   4559  N  N     . VAL C 1 128 ? 186.863 198.196 185.073 1.00 11.25  ? 128 VAL C N     1 
ATOM   4560  C  CA    . VAL C 1 128 ? 185.929 199.305 185.068 1.00 11.43  ? 128 VAL C CA    1 
ATOM   4561  C  C     . VAL C 1 128 ? 186.325 200.323 184.002 1.00 10.97  ? 128 VAL C C     1 
ATOM   4562  O  O     . VAL C 1 128 ? 185.469 200.810 183.266 1.00 11.35  ? 128 VAL C O     1 
ATOM   4563  C  CB    . VAL C 1 128 ? 185.827 199.946 186.461 1.00 11.93  ? 128 VAL C CB    1 
ATOM   4564  C  CG1   . VAL C 1 128 ? 184.977 201.207 186.439 1.00 11.98  ? 128 VAL C CG1   1 
ATOM   4565  C  CG2   . VAL C 1 128 ? 185.276 198.940 187.459 1.00 12.20  ? 128 VAL C CG2   1 
ATOM   4566  N  N     . ILE C 1 129 ? 187.625 200.640 183.912 1.00 11.34  ? 129 ILE C N     1 
ATOM   4567  C  CA    . ILE C 1 129 ? 188.097 201.645 182.975 1.00 11.41  ? 129 ILE C CA    1 
ATOM   4568  C  C     . ILE C 1 129 ? 187.712 201.252 181.553 1.00 12.93  ? 129 ILE C C     1 
ATOM   4569  O  O     . ILE C 1 129 ? 187.172 202.067 180.800 1.00 13.51  ? 129 ILE C O     1 
ATOM   4570  C  CB    . ILE C 1 129 ? 189.616 201.859 183.106 1.00 11.55  ? 129 ILE C CB    1 
ATOM   4571  C  CG1   . ILE C 1 129 ? 189.948 202.658 184.367 1.00 11.61  ? 129 ILE C CG1   1 
ATOM   4572  C  CG2   . ILE C 1 129 ? 190.170 202.551 181.865 1.00 11.30  ? 129 ILE C CG2   1 
ATOM   4573  C  CD1   . ILE C 1 129 ? 191.429 202.676 184.705 1.00 11.52  ? 129 ILE C CD1   1 
ATOM   4574  N  N     . ARG C 1 130 ? 188.029 200.020 181.155 1.00 13.19  ? 130 ARG C N     1 
ATOM   4575  C  CA    . ARG C 1 130 ? 187.838 199.611 179.773 1.00 14.85  ? 130 ARG C CA    1 
ATOM   4576  C  C     . ARG C 1 130 ? 186.360 199.572 179.393 1.00 14.39  ? 130 ARG C C     1 
ATOM   4577  O  O     . ARG C 1 130 ? 186.040 199.744 178.228 1.00 15.77  ? 130 ARG C O     1 
ATOM   4578  C  CB    . ARG C 1 130 ? 188.502 198.261 179.499 1.00 14.86  ? 130 ARG C CB    1 
ATOM   4579  C  CG    . ARG C 1 130 ? 187.662 197.067 179.916 1.00 15.78  ? 130 ARG C CG    1 
ATOM   4580  C  CD    . ARG C 1 130 ? 188.517 195.849 180.130 1.00 16.48  ? 130 ARG C CD    1 
ATOM   4581  N  NE    . ARG C 1 130 ? 187.683 194.763 180.648 1.00 17.02  ? 130 ARG C NE    1 
ATOM   4582  C  CZ    . ARG C 1 130 ? 186.856 194.033 179.937 1.00 18.16  ? 130 ARG C CZ    1 
ATOM   4583  N  NH1   . ARG C 1 130 ? 186.793 194.120 178.631 1.00 17.62  ? 130 ARG C NH1   1 
ATOM   4584  N  NH2   . ARG C 1 130 ? 186.143 193.131 180.559 1.00 20.06  ? 130 ARG C NH2   1 
ATOM   4585  N  N     . LEU C 1 131 ? 185.470 199.336 180.362 1.00 15.00  ? 131 LEU C N     1 
ATOM   4586  C  CA    . LEU C 1 131 ? 184.040 199.253 180.082 1.00 14.34  ? 131 LEU C CA    1 
ATOM   4587  C  C     . LEU C 1 131 ? 183.357 200.614 180.170 1.00 15.36  ? 131 LEU C C     1 
ATOM   4588  O  O     . LEU C 1 131 ? 182.444 200.883 179.395 1.00 16.09  ? 131 LEU C O     1 
ATOM   4589  C  CB    . LEU C 1 131 ? 183.388 198.248 181.021 1.00 14.90  ? 131 LEU C CB    1 
ATOM   4590  C  CG    . LEU C 1 131 ? 183.788 196.788 180.812 1.00 15.08  ? 131 LEU C CG    1 
ATOM   4591  C  CD1   . LEU C 1 131 ? 183.233 195.915 181.906 1.00 15.27  ? 131 LEU C CD1   1 
ATOM   4592  C  CD2   . LEU C 1 131 ? 183.328 196.281 179.451 1.00 16.35  ? 131 LEU C CD2   1 
ATOM   4593  N  N     . VAL C 1 132 ? 183.762 201.474 181.103 1.00 15.16  ? 132 VAL C N     1 
ATOM   4594  C  CA    . VAL C 1 132 ? 183.189 202.809 181.170 1.00 16.07  ? 132 VAL C CA    1 
ATOM   4595  C  C     . VAL C 1 132 ? 183.658 203.652 179.981 1.00 14.97  ? 132 VAL C C     1 
ATOM   4596  O  O     . VAL C 1 132 ? 182.964 204.575 179.557 1.00 15.18  ? 132 VAL C O     1 
ATOM   4597  C  CB    . VAL C 1 132 ? 183.490 203.518 182.501 1.00 17.34  ? 132 VAL C CB    1 
ATOM   4598  C  CG1   . VAL C 1 132 ? 183.012 202.697 183.681 1.00 20.61  ? 132 VAL C CG1   1 
ATOM   4599  C  CG2   . VAL C 1 132 ? 184.963 203.861 182.638 1.00 17.93  ? 132 VAL C CG2   1 
ATOM   4600  N  N     . ALA C 1 133 ? 184.861 203.369 179.468 1.00 15.43  ? 133 ALA C N     1 
ATOM   4601  C  CA    . ALA C 1 133 ? 185.368 204.090 178.308 1.00 16.06  ? 133 ALA C CA    1 
ATOM   4602  C  C     . ALA C 1 133 ? 184.440 203.884 177.113 1.00 16.92  ? 133 ALA C C     1 
ATOM   4603  O  O     . ALA C 1 133 ? 184.172 204.816 176.360 1.00 16.76  ? 133 ALA C O     1 
ATOM   4604  C  CB    . ALA C 1 133 ? 186.783 203.672 177.989 1.00 16.64  ? 133 ALA C CB    1 
ATOM   4605  N  N     . GLY C 1 134 ? 183.954 202.652 176.930 1.00 18.68  ? 134 GLY C N     1 
ATOM   4606  C  CA    . GLY C 1 134 ? 182.975 202.367 175.894 1.00 19.65  ? 134 GLY C CA    1 
ATOM   4607  C  C     . GLY C 1 134 ? 181.683 203.148 176.107 1.00 21.45  ? 134 GLY C C     1 
ATOM   4608  O  O     . GLY C 1 134 ? 181.113 203.678 175.152 1.00 23.16  ? 134 GLY C O     1 
ATOM   4609  N  N     . GLU C 1 135 ? 181.231 203.228 177.360 1.00 22.23  ? 135 GLU C N     1 
ATOM   4610  C  CA    . GLU C 1 135 ? 180.033 203.984 177.685 1.00 23.04  ? 135 GLU C CA    1 
ATOM   4611  C  C     . GLU C 1 135 ? 180.264 205.476 177.439 1.00 21.31  ? 135 GLU C C     1 
ATOM   4612  O  O     . GLU C 1 135 ? 179.412 206.155 176.873 1.00 21.82  ? 135 GLU C O     1 
ATOM   4613  C  CB    . GLU C 1 135 ? 179.602 203.759 179.134 1.00 27.33  ? 135 GLU C CB    1 
ATOM   4614  C  CG    . GLU C 1 135 ? 179.314 202.304 179.476 1.00 32.54  ? 135 GLU C CG    1 
ATOM   4615  C  CD    . GLU C 1 135 ? 178.292 201.675 178.548 1.00 37.60  ? 135 GLU C CD    1 
ATOM   4616  O  OE1   . GLU C 1 135 ? 177.151 202.169 178.563 1.00 40.62  ? 135 GLU C OE1   1 
ATOM   4617  O  OE2   . GLU C 1 135 ? 178.625 200.716 177.809 1.00 42.38  ? 135 GLU C OE2   1 
ATOM   4618  N  N     . MET C 1 136 ? 181.416 205.999 177.869 1.00 19.19  ? 136 MET C N     1 
ATOM   4619  C  CA    . MET C 1 136 ? 181.715 207.408 177.689 1.00 18.14  ? 136 MET C CA    1 
ATOM   4620  C  C     . MET C 1 136 ? 181.927 207.735 176.209 1.00 18.39  ? 136 MET C C     1 
ATOM   4621  O  O     . MET C 1 136 ? 181.635 208.851 175.781 1.00 18.42  ? 136 MET C O     1 
ATOM   4622  C  CB    . MET C 1 136 ? 182.964 207.808 178.483 1.00 17.06  ? 136 MET C CB    1 
ATOM   4623  C  CG    . MET C 1 136 ? 182.750 207.976 179.958 1.00 15.99  ? 136 MET C CG    1 
ATOM   4624  S  SD    . MET C 1 136 ? 184.317 208.016 180.849 1.00 15.46  ? 136 MET C SD    1 
ATOM   4625  C  CE    . MET C 1 136 ? 183.719 208.112 182.540 1.00 15.49  ? 136 MET C CE    1 
ATOM   4626  N  N     . GLY C 1 137 ? 182.439 206.775 175.433 1.00 19.90  ? 137 GLY C N     1 
ATOM   4627  C  CA    . GLY C 1 137 ? 182.659 206.982 174.010 1.00 22.41  ? 137 GLY C CA    1 
ATOM   4628  C  C     . GLY C 1 137 ? 181.370 207.326 173.257 1.00 24.43  ? 137 GLY C C     1 
ATOM   4629  O  O     . GLY C 1 137 ? 181.417 207.962 172.212 1.00 26.14  ? 137 GLY C O     1 
ATOM   4630  N  N     . GLN C 1 138 ? 180.223 206.893 173.785 1.00 26.69  ? 138 GLN C N     1 
ATOM   4631  C  CA    . GLN C 1 138 ? 178.942 207.166 173.155 1.00 29.09  ? 138 GLN C CA    1 
ATOM   4632  C  C     . GLN C 1 138 ? 178.466 208.594 173.414 1.00 26.98  ? 138 GLN C C     1 
ATOM   4633  O  O     . GLN C 1 138 ? 177.522 209.043 172.769 1.00 27.48  ? 138 GLN C O     1 
ATOM   4634  C  CB    . GLN C 1 138 ? 177.887 206.186 173.663 1.00 32.61  ? 138 GLN C CB    1 
ATOM   4635  C  CG    . GLN C 1 138 ? 178.134 204.745 173.243 1.00 38.55  ? 138 GLN C CG    1 
ATOM   4636  C  CD    . GLN C 1 138 ? 177.150 203.775 173.859 1.00 47.26  ? 138 GLN C CD    1 
ATOM   4637  O  OE1   . GLN C 1 138 ? 176.256 204.143 174.630 1.00 50.08  ? 138 GLN C OE1   1 
ATOM   4638  N  NE2   . GLN C 1 138 ? 177.326 202.507 173.520 1.00 53.99  ? 138 GLN C NE2   1 
ATOM   4639  N  N     . ASN C 1 139 ? 179.081 209.302 174.366 1.00 25.04  ? 139 ASN C N     1 
ATOM   4640  C  CA    . ASN C 1 139 ? 178.682 210.666 174.669 1.00 24.95  ? 139 ASN C CA    1 
ATOM   4641  C  C     . ASN C 1 139 ? 179.056 211.594 173.515 1.00 25.45  ? 139 ASN C C     1 
ATOM   4642  O  O     . ASN C 1 139 ? 180.080 211.418 172.867 1.00 24.72  ? 139 ASN C O     1 
ATOM   4643  C  CB    . ASN C 1 139 ? 179.320 211.167 175.959 1.00 24.28  ? 139 ASN C CB    1 
ATOM   4644  C  CG    . ASN C 1 139 ? 178.827 210.431 177.178 1.00 25.73  ? 139 ASN C CG    1 
ATOM   4645  O  OD1   . ASN C 1 139 ? 177.756 209.806 177.151 1.00 25.78  ? 139 ASN C OD1   1 
ATOM   4646  N  ND2   . ASN C 1 139 ? 179.603 210.478 178.253 1.00 24.52  ? 139 ASN C ND2   1 
ATOM   4647  N  N     . GLU C 1 140 ? 178.221 212.598 173.268 1.00 27.28  ? 140 GLU C N     1 
ATOM   4648  C  CA    . GLU C 1 140 ? 178.605 213.679 172.384 1.00 29.58  ? 140 GLU C CA    1 
ATOM   4649  C  C     . GLU C 1 140 ? 179.657 214.536 173.077 1.00 28.60  ? 140 GLU C C     1 
ATOM   4650  O  O     . GLU C 1 140 ? 179.474 214.923 174.229 1.00 28.14  ? 140 GLU C O     1 
ATOM   4651  C  CB    . GLU C 1 140 ? 177.403 214.538 171.988 1.00 34.78  ? 140 GLU C CB    1 
ATOM   4652  C  CG    . GLU C 1 140 ? 176.628 213.973 170.801 1.00 42.12  ? 140 GLU C CG    1 
ATOM   4653  C  CD    . GLU C 1 140 ? 177.537 213.795 169.593 1.00 50.69  ? 140 GLU C CD    1 
ATOM   4654  O  OE1   . GLU C 1 140 ? 177.537 212.698 168.980 1.00 50.94  ? 140 GLU C OE1   1 
ATOM   4655  O  OE2   . GLU C 1 140 ? 178.269 214.770 169.289 1.00 55.00  ? 140 GLU C OE2   1 
ATOM   4656  N  N     . PRO C 1 141 ? 180.780 214.867 172.411 1.00 26.75  ? 141 PRO C N     1 
ATOM   4657  C  CA    . PRO C 1 141 ? 181.793 215.709 173.037 1.00 26.67  ? 141 PRO C CA    1 
ATOM   4658  C  C     . PRO C 1 141 ? 181.223 217.068 173.430 1.00 29.40  ? 141 PRO C C     1 
ATOM   4659  O  O     . PRO C 1 141 ? 180.379 217.622 172.728 1.00 30.57  ? 141 PRO C O     1 
ATOM   4660  C  CB    . PRO C 1 141 ? 182.892 215.840 171.989 1.00 26.42  ? 141 PRO C CB    1 
ATOM   4661  C  CG    . PRO C 1 141 ? 182.621 214.754 170.978 1.00 27.65  ? 141 PRO C CG    1 
ATOM   4662  C  CD    . PRO C 1 141 ? 181.160 214.398 171.073 1.00 26.35  ? 141 PRO C CD    1 
ATOM   4663  N  N     . ASP C 1 142 ? 181.698 217.603 174.561 1.00 28.66  ? 142 ASP C N     1 
ATOM   4664  C  CA    . ASP C 1 142 ? 181.296 218.927 175.005 1.00 30.82  ? 142 ASP C CA    1 
ATOM   4665  C  C     . ASP C 1 142 ? 182.019 219.981 174.168 1.00 32.08  ? 142 ASP C C     1 
ATOM   4666  O  O     . ASP C 1 142 ? 182.704 219.664 173.198 1.00 32.76  ? 142 ASP C O     1 
ATOM   4667  C  CB    . ASP C 1 142 ? 181.518 219.065 176.499 1.00 31.19  ? 142 ASP C CB    1 
ATOM   4668  C  CG    . ASP C 1 142 ? 182.977 219.066 176.933 1.00 33.94  ? 142 ASP C CG    1 
ATOM   4669  O  OD1   . ASP C 1 142 ? 183.882 219.005 176.051 1.00 34.08  ? 142 ASP C OD1   1 
ATOM   4670  O  OD2   . ASP C 1 142 ? 183.211 219.132 178.158 1.00 36.90  ? 142 ASP C OD2   1 
ATOM   4671  N  N     . GLN C 1 143 ? 181.885 221.251 174.554 1.00 37.86  ? 143 GLN C N     1 
ATOM   4672  C  CA    . GLN C 1 143 ? 182.498 222.327 173.784 1.00 42.95  ? 143 GLN C CA    1 
ATOM   4673  C  C     . GLN C 1 143 ? 184.021 222.190 173.790 1.00 40.77  ? 143 GLN C C     1 
ATOM   4674  O  O     . GLN C 1 143 ? 184.683 222.644 172.860 1.00 42.41  ? 143 GLN C O     1 
ATOM   4675  C  CB    . GLN C 1 143 ? 182.059 223.696 174.304 1.00 51.48  ? 143 GLN C CB    1 
ATOM   4676  C  CG    . GLN C 1 143 ? 182.725 224.145 175.603 1.00 61.65  ? 143 GLN C CG    1 
ATOM   4677  C  CD    . GLN C 1 143 ? 182.310 223.336 176.813 1.00 69.57  ? 143 GLN C CD    1 
ATOM   4678  O  OE1   . GLN C 1 143 ? 181.259 222.683 176.808 1.00 71.14  ? 143 GLN C OE1   1 
ATOM   4679  N  NE2   . GLN C 1 143 ? 183.123 223.383 177.860 1.00 75.02  ? 143 GLN C NE2   1 
ATOM   4680  N  N     . GLY C 1 144 ? 184.575 221.583 174.850 1.00 35.65  ? 144 GLY C N     1 
ATOM   4681  C  CA    . GLY C 1 144 ? 186.007 221.348 174.945 1.00 31.51  ? 144 GLY C CA    1 
ATOM   4682  C  C     . GLY C 1 144 ? 186.457 220.032 174.315 1.00 28.53  ? 144 GLY C C     1 
ATOM   4683  O  O     . GLY C 1 144 ? 187.631 219.685 174.391 1.00 30.13  ? 144 GLY C O     1 
ATOM   4684  N  N     . GLY C 1 145 ? 185.533 219.280 173.709 1.00 25.98  ? 145 GLY C N     1 
ATOM   4685  C  CA    . GLY C 1 145 ? 185.877 218.015 173.088 1.00 24.54  ? 145 GLY C CA    1 
ATOM   4686  C  C     . GLY C 1 145 ? 185.932 216.852 174.083 1.00 23.28  ? 145 GLY C C     1 
ATOM   4687  O  O     . GLY C 1 145 ? 186.357 215.762 173.709 1.00 22.63  ? 145 GLY C O     1 
ATOM   4688  N  N     . GLN C 1 146 ? 185.488 217.072 175.327 1.00 20.82  ? 146 GLN C N     1 
ATOM   4689  C  CA    . GLN C 1 146 ? 185.619 216.064 176.369 1.00 19.79  ? 146 GLN C CA    1 
ATOM   4690  C  C     . GLN C 1 146 ? 184.383 215.173 176.395 1.00 17.51  ? 146 GLN C C     1 
ATOM   4691  O  O     . GLN C 1 146 ? 183.263 215.660 176.381 1.00 17.01  ? 146 GLN C O     1 
ATOM   4692  C  CB    . GLN C 1 146 ? 185.828 216.733 177.726 1.00 19.86  ? 146 GLN C CB    1 
ATOM   4693  C  CG    . GLN C 1 146 ? 185.987 215.756 178.882 1.00 20.87  ? 146 GLN C CG    1 
ATOM   4694  C  CD    . GLN C 1 146 ? 186.209 216.459 180.198 1.00 21.89  ? 146 GLN C CD    1 
ATOM   4695  O  OE1   . GLN C 1 146 ? 187.317 216.908 180.501 1.00 23.49  ? 146 GLN C OE1   1 
ATOM   4696  N  NE2   . GLN C 1 146 ? 185.157 216.556 180.995 1.00 22.28  ? 146 GLN C NE2   1 
ATOM   4697  N  N     . ARG C 1 147 ? 184.612 213.859 176.473 1.00 15.58  ? 147 ARG C N     1 
ATOM   4698  C  CA    . ARG C 1 147 ? 183.536 212.889 176.570 1.00 15.16  ? 147 ARG C CA    1 
ATOM   4699  C  C     . ARG C 1 147 ? 183.390 212.330 177.981 1.00 13.96  ? 147 ARG C C     1 
ATOM   4700  O  O     . ARG C 1 147 ? 182.324 211.834 178.339 1.00 15.08  ? 147 ARG C O     1 
ATOM   4701  C  CB    . ARG C 1 147 ? 183.774 211.716 175.612 1.00 17.68  ? 147 ARG C CB    1 
ATOM   4702  C  CG    . ARG C 1 147 ? 183.466 212.045 174.159 1.00 19.68  ? 147 ARG C CG    1 
ATOM   4703  C  CD    . ARG C 1 147 ? 183.148 210.794 173.382 1.00 22.35  ? 147 ARG C CD    1 
ATOM   4704  N  NE    . ARG C 1 147 ? 182.845 211.038 171.972 1.00 25.54  ? 147 ARG C NE    1 
ATOM   4705  C  CZ    . ARG C 1 147 ? 183.700 211.454 171.054 1.00 28.35  ? 147 ARG C CZ    1 
ATOM   4706  N  NH1   . ARG C 1 147 ? 184.948 211.694 171.379 1.00 27.56  ? 147 ARG C NH1   1 
ATOM   4707  N  NH2   . ARG C 1 147 ? 183.296 211.638 169.811 1.00 30.88  ? 147 ARG C NH2   1 
ATOM   4708  N  N     . GLY C 1 148 ? 184.442 212.391 178.799 1.00 11.67  ? 148 GLY C N     1 
ATOM   4709  C  CA    . GLY C 1 148 ? 184.344 211.863 180.143 1.00 10.72  ? 148 GLY C CA    1 
ATOM   4710  C  C     . GLY C 1 148 ? 185.645 212.036 180.906 1.00 9.55   ? 148 GLY C C     1 
ATOM   4711  O  O     . GLY C 1 148 ? 186.657 212.439 180.342 1.00 8.80   ? 148 GLY C O     1 
ATOM   4712  N  N     . VAL C 1 149 ? 185.577 211.740 182.202 1.00 9.55   ? 149 VAL C N     1 
ATOM   4713  C  CA    . VAL C 1 149 ? 186.731 211.789 183.079 1.00 9.52   ? 149 VAL C CA    1 
ATOM   4714  C  C     . VAL C 1 149 ? 186.742 210.504 183.894 1.00 8.74   ? 149 VAL C C     1 
ATOM   4715  O  O     . VAL C 1 149 ? 185.723 210.125 184.476 1.00 9.05   ? 149 VAL C O     1 
ATOM   4716  C  CB    . VAL C 1 149 ? 186.703 213.021 184.010 1.00 10.47  ? 149 VAL C CB    1 
ATOM   4717  C  CG1   . VAL C 1 149 ? 187.995 213.133 184.811 1.00 10.78  ? 149 VAL C CG1   1 
ATOM   4718  C  CG2   . VAL C 1 149 ? 186.457 214.302 183.230 1.00 11.53  ? 149 VAL C CG2   1 
ATOM   4719  N  N     . ILE C 1 150 ? 187.908 209.863 183.957 1.00 8.39   ? 150 ILE C N     1 
ATOM   4720  C  CA    . ILE C 1 150 ? 188.102 208.692 184.790 1.00 8.44   ? 150 ILE C CA    1 
ATOM   4721  C  C     . ILE C 1 150 ? 189.142 209.024 185.853 1.00 8.24   ? 150 ILE C C     1 
ATOM   4722  O  O     . ILE C 1 150 ? 190.249 209.456 185.529 1.00 8.01   ? 150 ILE C O     1 
ATOM   4723  C  CB    . ILE C 1 150 ? 188.530 207.473 183.956 1.00 8.83   ? 150 ILE C CB    1 
ATOM   4724  C  CG1   . ILE C 1 150 ? 187.498 207.135 182.900 1.00 8.89   ? 150 ILE C CG1   1 
ATOM   4725  C  CG2   . ILE C 1 150 ? 188.845 206.284 184.870 1.00 9.33   ? 150 ILE C CG2   1 
ATOM   4726  C  CD1   . ILE C 1 150 ? 187.937 206.068 181.916 1.00 9.12   ? 150 ILE C CD1   1 
ATOM   4727  N  N     . ILE C 1 151 ? 188.762 208.818 187.117 1.00 8.49   ? 151 ILE C N     1 
ATOM   4728  C  CA    . ILE C 1 151 ? 189.639 209.080 188.241 1.00 8.80   ? 151 ILE C CA    1 
ATOM   4729  C  C     . ILE C 1 151 ? 189.870 207.776 188.988 1.00 8.94   ? 151 ILE C C     1 
ATOM   4730  O  O     . ILE C 1 151 ? 188.924 207.149 189.461 1.00 9.46   ? 151 ILE C O     1 
ATOM   4731  C  CB    . ILE C 1 151 ? 189.060 210.170 189.159 1.00 9.52   ? 151 ILE C CB    1 
ATOM   4732  C  CG1   . ILE C 1 151 ? 188.941 211.484 188.416 1.00 10.19  ? 151 ILE C CG1   1 
ATOM   4733  C  CG2   . ILE C 1 151 ? 189.913 210.322 190.417 1.00 9.25   ? 151 ILE C CG2   1 
ATOM   4734  C  CD1   . ILE C 1 151 ? 187.735 212.293 188.802 1.00 11.09  ? 151 ILE C CD1   1 
ATOM   4735  N  N     . ASN C 1 152 ? 191.145 207.397 189.104 1.00 8.88   ? 152 ASN C N     1 
ATOM   4736  C  CA    . ASN C 1 152 ? 191.536 206.185 189.795 1.00 9.18   ? 152 ASN C CA    1 
ATOM   4737  C  C     . ASN C 1 152 ? 192.113 206.530 191.161 1.00 9.28   ? 152 ASN C C     1 
ATOM   4738  O  O     . ASN C 1 152 ? 192.578 207.638 191.403 1.00 9.64   ? 152 ASN C O     1 
ATOM   4739  C  CB    . ASN C 1 152 ? 192.557 205.398 188.991 1.00 9.46   ? 152 ASN C CB    1 
ATOM   4740  C  CG    . ASN C 1 152 ? 192.155 205.266 187.544 1.00 10.28  ? 152 ASN C CG    1 
ATOM   4741  O  OD1   . ASN C 1 152 ? 191.112 204.684 187.243 1.00 10.50  ? 152 ASN C OD1   1 
ATOM   4742  N  ND2   . ASN C 1 152 ? 192.966 205.787 186.634 1.00 11.18  ? 152 ASN C ND2   1 
ATOM   4743  N  N     . THR C 1 153 ? 192.081 205.550 192.054 1.00 10.24  ? 153 THR C N     1 
ATOM   4744  C  CA    . THR C 1 153 ? 192.629 205.686 193.386 1.00 10.95  ? 153 THR C CA    1 
ATOM   4745  C  C     . THR C 1 153 ? 193.827 204.747 193.507 1.00 11.54  ? 153 THR C C     1 
ATOM   4746  O  O     . THR C 1 153 ? 193.669 203.532 193.633 1.00 11.79  ? 153 THR C O     1 
ATOM   4747  C  CB    . THR C 1 153 ? 191.580 205.382 194.445 1.00 11.37  ? 153 THR C CB    1 
ATOM   4748  O  OG1   . THR C 1 153 ? 190.421 206.172 194.201 1.00 12.05  ? 153 THR C OG1   1 
ATOM   4749  C  CG2   . THR C 1 153 ? 192.103 205.680 195.839 1.00 11.41  ? 153 THR C CG2   1 
ATOM   4750  N  N     . ALA C 1 154 ? 195.022 205.345 193.504 1.00 12.05  ? 154 ALA C N     1 
ATOM   4751  C  CA    . ALA C 1 154 ? 196.241 204.644 193.869 1.00 12.01  ? 154 ALA C CA    1 
ATOM   4752  C  C     . ALA C 1 154 ? 196.436 204.809 195.373 1.00 13.10  ? 154 ALA C C     1 
ATOM   4753  O  O     . ALA C 1 154 ? 195.486 205.048 196.103 1.00 15.45  ? 154 ALA C O     1 
ATOM   4754  C  CB    . ALA C 1 154 ? 197.413 205.176 193.069 1.00 11.83  ? 154 ALA C CB    1 
ATOM   4755  N  N     . SER C 1 155 ? 197.669 204.664 195.846 1.00 12.72  ? 155 SER C N     1 
ATOM   4756  C  CA    . SER C 1 155 ? 198.005 204.974 197.230 1.00 12.25  ? 155 SER C CA    1 
ATOM   4757  C  C     . SER C 1 155 ? 199.419 205.544 197.256 1.00 12.11  ? 155 SER C C     1 
ATOM   4758  O  O     . SER C 1 155 ? 200.187 205.374 196.307 1.00 12.48  ? 155 SER C O     1 
ATOM   4759  C  CB    . SER C 1 155 ? 197.927 203.718 198.099 1.00 12.25  ? 155 SER C CB    1 
ATOM   4760  O  OG    . SER C 1 155 ? 198.222 204.033 199.448 1.00 12.99  ? 155 SER C OG    1 
ATOM   4761  N  N     . VAL C 1 156 ? 199.774 206.195 198.356 1.00 12.36  ? 156 VAL C N     1 
ATOM   4762  C  CA    . VAL C 1 156 ? 201.165 206.546 198.588 1.00 12.99  ? 156 VAL C CA    1 
ATOM   4763  C  C     . VAL C 1 156 ? 202.027 205.284 198.654 1.00 11.92  ? 156 VAL C C     1 
ATOM   4764  O  O     . VAL C 1 156 ? 203.240 205.347 198.461 1.00 12.40  ? 156 VAL C O     1 
ATOM   4765  C  CB    . VAL C 1 156 ? 201.317 207.389 199.867 1.00 14.68  ? 156 VAL C CB    1 
ATOM   4766  C  CG1   . VAL C 1 156 ? 200.701 208.769 199.662 1.00 15.61  ? 156 VAL C CG1   1 
ATOM   4767  C  CG2   . VAL C 1 156 ? 200.730 206.680 201.076 1.00 14.96  ? 156 VAL C CG2   1 
ATOM   4768  N  N     . ALA C 1 157 ? 201.413 204.132 198.946 1.00 10.62  ? 157 ALA C N     1 
ATOM   4769  C  CA    . ALA C 1 157 ? 202.125 202.862 198.940 1.00 10.22  ? 157 ALA C CA    1 
ATOM   4770  C  C     . ALA C 1 157 ? 202.666 202.527 197.551 1.00 10.17  ? 157 ALA C C     1 
ATOM   4771  O  O     . ALA C 1 157 ? 203.585 201.723 197.448 1.00 10.79  ? 157 ALA C O     1 
ATOM   4772  C  CB    . ALA C 1 157 ? 201.230 201.757 199.426 1.00 10.34  ? 157 ALA C CB    1 
ATOM   4773  N  N     . ALA C 1 158 ? 202.136 203.158 196.494 1.00 9.68   ? 158 ALA C N     1 
ATOM   4774  C  CA    . ALA C 1 158 ? 202.700 202.991 195.161 1.00 10.63  ? 158 ALA C CA    1 
ATOM   4775  C  C     . ALA C 1 158 ? 204.118 203.563 195.075 1.00 11.61  ? 158 ALA C C     1 
ATOM   4776  O  O     . ALA C 1 158 ? 204.900 203.141 194.228 1.00 11.87  ? 158 ALA C O     1 
ATOM   4777  C  CB    . ALA C 1 158 ? 201.804 203.616 194.124 1.00 10.30  ? 158 ALA C CB    1 
ATOM   4778  N  N     . PHE C 1 159 ? 204.458 204.495 195.976 1.00 12.68  ? 159 PHE C N     1 
ATOM   4779  C  CA    . PHE C 1 159 ? 205.746 205.174 195.939 1.00 14.33  ? 159 PHE C CA    1 
ATOM   4780  C  C     . PHE C 1 159 ? 206.630 204.760 197.112 1.00 15.17  ? 159 PHE C C     1 
ATOM   4781  O  O     . PHE C 1 159 ? 207.816 204.496 196.917 1.00 16.95  ? 159 PHE C O     1 
ATOM   4782  C  CB    . PHE C 1 159 ? 205.553 206.690 195.953 1.00 15.25  ? 159 PHE C CB    1 
ATOM   4783  C  CG    . PHE C 1 159 ? 204.617 207.175 194.864 1.00 15.44  ? 159 PHE C CG    1 
ATOM   4784  C  CD1   . PHE C 1 159 ? 205.017 207.159 193.540 1.00 16.62  ? 159 PHE C CD1   1 
ATOM   4785  C  CD2   . PHE C 1 159 ? 203.340 207.620 195.177 1.00 15.85  ? 159 PHE C CD2   1 
ATOM   4786  C  CE1   . PHE C 1 159 ? 204.154 207.581 192.537 1.00 17.06  ? 159 PHE C CE1   1 
ATOM   4787  C  CE2   . PHE C 1 159 ? 202.484 208.047 194.178 1.00 16.34  ? 159 PHE C CE2   1 
ATOM   4788  C  CZ    . PHE C 1 159 ? 202.894 208.033 192.861 1.00 16.86  ? 159 PHE C CZ    1 
ATOM   4789  N  N     . GLU C 1 160 ? 206.062 204.716 198.324 1.00 15.97  ? 160 GLU C N     1 
ATOM   4790  C  CA    . GLU C 1 160 ? 206.788 204.213 199.476 1.00 18.91  ? 160 GLU C CA    1 
ATOM   4791  C  C     . GLU C 1 160 ? 205.931 203.197 200.218 1.00 16.68  ? 160 GLU C C     1 
ATOM   4792  O  O     . GLU C 1 160 ? 205.263 203.523 201.185 1.00 18.21  ? 160 GLU C O     1 
ATOM   4793  C  CB    . GLU C 1 160 ? 207.326 205.311 200.393 1.00 23.88  ? 160 GLU C CB    1 
ATOM   4794  C  CG    . GLU C 1 160 ? 206.284 206.225 201.007 1.00 29.96  ? 160 GLU C CG    1 
ATOM   4795  C  CD    . GLU C 1 160 ? 205.841 207.394 200.146 1.00 33.04  ? 160 GLU C CD    1 
ATOM   4796  O  OE1   . GLU C 1 160 ? 206.163 207.393 198.954 1.00 37.60  ? 160 GLU C OE1   1 
ATOM   4797  O  OE2   . GLU C 1 160 ? 205.175 208.292 200.679 1.00 36.54  ? 160 GLU C OE2   1 
ATOM   4798  N  N     . GLY C 1 161 ? 205.941 201.950 199.735 1.00 14.28  ? 161 GLY C N     1 
ATOM   4799  C  CA    . GLY C 1 161 ? 205.226 200.888 200.409 1.00 12.67  ? 161 GLY C CA    1 
ATOM   4800  C  C     . GLY C 1 161 ? 205.992 200.438 201.654 1.00 12.17  ? 161 GLY C C     1 
ATOM   4801  O  O     . GLY C 1 161 ? 207.217 200.320 201.643 1.00 12.03  ? 161 GLY C O     1 
ATOM   4802  N  N     . GLN C 1 162 ? 205.254 200.171 202.725 1.00 12.26  ? 162 GLN C N     1 
ATOM   4803  C  CA    . GLN C 1 162 ? 205.850 199.769 203.988 1.00 13.91  ? 162 GLN C CA    1 
ATOM   4804  C  C     . GLN C 1 162 ? 206.101 198.264 203.999 1.00 12.97  ? 162 GLN C C     1 
ATOM   4805  O  O     . GLN C 1 162 ? 205.764 197.551 203.062 1.00 12.51  ? 162 GLN C O     1 
ATOM   4806  C  CB    . GLN C 1 162 ? 204.938 200.161 205.148 1.00 16.48  ? 162 GLN C CB    1 
ATOM   4807  C  CG    . GLN C 1 162 ? 204.623 201.649 205.189 1.00 20.43  ? 162 GLN C CG    1 
ATOM   4808  C  CD    . GLN C 1 162 ? 203.940 202.054 206.465 1.00 24.61  ? 162 GLN C CD    1 
ATOM   4809  O  OE1   . GLN C 1 162 ? 202.719 201.931 206.598 1.00 28.99  ? 162 GLN C OE1   1 
ATOM   4810  N  NE2   . GLN C 1 162 ? 204.735 202.541 207.406 1.00 27.00  ? 162 GLN C NE2   1 
ATOM   4811  N  N     . VAL C 1 163 ? 206.739 197.785 205.072 1.00 12.68  ? 163 VAL C N     1 
ATOM   4812  C  CA    . VAL C 1 163 ? 206.907 196.361 205.280 1.00 12.91  ? 163 VAL C CA    1 
ATOM   4813  C  C     . VAL C 1 163 ? 205.534 195.695 205.322 1.00 11.56  ? 163 VAL C C     1 
ATOM   4814  O  O     . VAL C 1 163 ? 204.638 196.134 206.029 1.00 11.24  ? 163 VAL C O     1 
ATOM   4815  C  CB    . VAL C 1 163 ? 207.697 196.092 206.571 1.00 14.00  ? 163 VAL C CB    1 
ATOM   4816  C  CG1   . VAL C 1 163 ? 207.652 194.621 206.949 1.00 14.74  ? 163 VAL C CG1   1 
ATOM   4817  C  CG2   . VAL C 1 163 ? 209.131 196.574 206.445 1.00 14.50  ? 163 VAL C CG2   1 
ATOM   4818  N  N     . GLY C 1 164 ? 205.386 194.607 204.568 1.00 10.74  ? 164 GLY C N     1 
ATOM   4819  C  CA    . GLY C 1 164 ? 204.133 193.878 204.526 1.00 10.43  ? 164 GLY C CA    1 
ATOM   4820  C  C     . GLY C 1 164 ? 203.182 194.389 203.443 1.00 10.23  ? 164 GLY C C     1 
ATOM   4821  O  O     . GLY C 1 164 ? 202.082 193.849 203.311 1.00 10.89  ? 164 GLY C O     1 
ATOM   4822  N  N     . GLN C 1 165 ? 203.589 195.397 202.653 1.00 10.01  ? 165 GLN C N     1 
ATOM   4823  C  CA    . GLN C 1 165 ? 202.679 196.004 201.690 1.00 9.52   ? 165 GLN C CA    1 
ATOM   4824  C  C     . GLN C 1 165 ? 203.042 195.670 200.245 1.00 8.83   ? 165 GLN C C     1 
ATOM   4825  O  O     . GLN C 1 165 ? 202.638 196.395 199.342 1.00 9.00   ? 165 GLN C O     1 
ATOM   4826  C  CB    . GLN C 1 165 ? 202.625 197.525 201.867 1.00 10.29  ? 165 GLN C CB    1 
ATOM   4827  C  CG    . GLN C 1 165 ? 201.706 197.999 202.976 1.00 11.47  ? 165 GLN C CG    1 
ATOM   4828  C  CD    . GLN C 1 165 ? 201.436 199.481 202.905 1.00 12.63  ? 165 GLN C CD    1 
ATOM   4829  O  OE1   . GLN C 1 165 ? 202.363 200.282 202.772 1.00 12.92  ? 165 GLN C OE1   1 
ATOM   4830  N  NE2   . GLN C 1 165 ? 200.168 199.854 203.003 1.00 13.31  ? 165 GLN C NE2   1 
ATOM   4831  N  N     . ALA C 1 166 ? 203.778 194.581 200.023 1.00 8.32   ? 166 ALA C N     1 
ATOM   4832  C  CA    . ALA C 1 166 ? 204.223 194.226 198.684 1.00 8.30   ? 166 ALA C CA    1 
ATOM   4833  C  C     . ALA C 1 166 ? 203.038 194.085 197.725 1.00 7.96   ? 166 ALA C C     1 
ATOM   4834  O  O     . ALA C 1 166 ? 203.062 194.628 196.623 1.00 7.81   ? 166 ALA C O     1 
ATOM   4835  C  CB    . ALA C 1 166 ? 205.071 192.966 198.704 1.00 8.56   ? 166 ALA C CB    1 
ATOM   4836  N  N     . ALA C 1 167 ? 202.014 193.317 198.113 1.00 7.72   ? 167 ALA C N     1 
ATOM   4837  C  CA    . ALA C 1 167 ? 200.880 193.096 197.234 1.00 7.76   ? 167 ALA C CA    1 
ATOM   4838  C  C     . ALA C 1 167 ? 200.116 194.401 197.009 1.00 7.70   ? 167 ALA C C     1 
ATOM   4839  O  O     . ALA C 1 167 ? 199.729 194.701 195.892 1.00 7.82   ? 167 ALA C O     1 
ATOM   4840  C  CB    . ALA C 1 167 ? 199.971 192.037 197.831 1.00 7.93   ? 167 ALA C CB    1 
ATOM   4841  N  N     . TYR C 1 168 ? 199.884 195.170 198.068 1.00 7.40   ? 168 TYR C N     1 
ATOM   4842  C  CA    . TYR C 1 168 ? 199.156 196.422 197.951 1.00 8.01   ? 168 TYR C CA    1 
ATOM   4843  C  C     . TYR C 1 168 ? 199.933 197.403 197.072 1.00 7.23   ? 168 TYR C C     1 
ATOM   4844  O  O     . TYR C 1 168 ? 199.349 198.079 196.225 1.00 7.17   ? 168 TYR C O     1 
ATOM   4845  C  CB    . TYR C 1 168 ? 198.878 196.995 199.343 1.00 8.68   ? 168 TYR C CB    1 
ATOM   4846  C  CG    . TYR C 1 168 ? 197.910 198.163 199.346 1.00 9.99   ? 168 TYR C CG    1 
ATOM   4847  C  CD1   . TYR C 1 168 ? 196.568 197.973 199.040 1.00 10.82  ? 168 TYR C CD1   1 
ATOM   4848  C  CD2   . TYR C 1 168 ? 198.332 199.456 199.641 1.00 10.95  ? 168 TYR C CD2   1 
ATOM   4849  C  CE1   . TYR C 1 168 ? 195.677 199.033 199.039 1.00 12.06  ? 168 TYR C CE1   1 
ATOM   4850  C  CE2   . TYR C 1 168 ? 197.446 200.528 199.648 1.00 11.73  ? 168 TYR C CE2   1 
ATOM   4851  C  CZ    . TYR C 1 168 ? 196.116 200.310 199.351 1.00 12.49  ? 168 TYR C CZ    1 
ATOM   4852  O  OH    . TYR C 1 168 ? 195.246 201.356 199.352 1.00 14.40  ? 168 TYR C OH    1 
ATOM   4853  N  N     . SER C 1 169 ? 201.248 197.505 197.292 1.00 7.20   ? 169 SER C N     1 
ATOM   4854  C  CA    . SER C 1 169 ? 202.073 198.438 196.542 1.00 7.00   ? 169 SER C CA    1 
ATOM   4855  C  C     . SER C 1 169 ? 202.134 198.066 195.067 1.00 6.94   ? 169 SER C C     1 
ATOM   4856  O  O     . SER C 1 169 ? 202.105 198.962 194.213 1.00 7.11   ? 169 SER C O     1 
ATOM   4857  C  CB    . SER C 1 169 ? 203.461 198.532 197.136 1.00 7.49   ? 169 SER C CB    1 
ATOM   4858  O  OG    . SER C 1 169 ? 203.379 199.065 198.451 1.00 7.36   ? 169 SER C OG    1 
ATOM   4859  N  N     . ALA C 1 170 ? 202.228 196.765 194.766 1.00 6.57   ? 170 ALA C N     1 
ATOM   4860  C  CA    . ALA C 1 170 ? 202.250 196.310 193.382 1.00 6.77   ? 170 ALA C CA    1 
ATOM   4861  C  C     . ALA C 1 170 ? 200.968 196.738 192.671 1.00 6.84   ? 170 ALA C C     1 
ATOM   4862  O  O     . ALA C 1 170 ? 201.010 197.258 191.553 1.00 6.97   ? 170 ALA C O     1 
ATOM   4863  C  CB    . ALA C 1 170 ? 202.413 194.801 193.299 1.00 6.55   ? 170 ALA C CB    1 
ATOM   4864  N  N     . SER C 1 171 ? 199.819 196.493 193.304 1.00 6.90   ? 171 SER C N     1 
ATOM   4865  C  CA    . SER C 1 171 ? 198.542 196.830 192.696 1.00 7.25   ? 171 SER C CA    1 
ATOM   4866  C  C     . SER C 1 171 ? 198.415 198.338 192.500 1.00 7.40   ? 171 SER C C     1 
ATOM   4867  O  O     . SER C 1 171 ? 197.989 198.794 191.433 1.00 7.70   ? 171 SER C O     1 
ATOM   4868  C  CB    . SER C 1 171 ? 197.401 196.271 193.498 1.00 7.42   ? 171 SER C CB    1 
ATOM   4869  O  OG    . SER C 1 171 ? 197.282 196.941 194.735 1.00 7.18   ? 171 SER C OG    1 
ATOM   4870  N  N     . LYS C 1 172 ? 198.798 199.117 193.508 1.00 7.54   ? 172 LYS C N     1 
ATOM   4871  C  CA    . LYS C 1 172 ? 198.715 200.566 193.404 1.00 8.31   ? 172 LYS C CA    1 
ATOM   4872  C  C     . LYS C 1 172 ? 199.770 201.123 192.450 1.00 8.00   ? 172 LYS C C     1 
ATOM   4873  O  O     . LYS C 1 172 ? 199.513 202.094 191.745 1.00 8.10   ? 172 LYS C O     1 
ATOM   4874  C  CB    . LYS C 1 172 ? 198.830 201.215 194.787 1.00 9.27   ? 172 LYS C CB    1 
ATOM   4875  C  CG    . LYS C 1 172 ? 197.666 200.876 195.697 1.00 10.37  ? 172 LYS C CG    1 
ATOM   4876  C  CD    . LYS C 1 172 ? 196.312 200.928 195.004 1.00 11.42  ? 172 LYS C CD    1 
ATOM   4877  C  CE    . LYS C 1 172 ? 195.161 200.905 195.972 1.00 12.53  ? 172 LYS C CE    1 
ATOM   4878  N  NZ    . LYS C 1 172 ? 193.929 201.382 195.324 1.00 13.09  ? 172 LYS C NZ    1 
ATOM   4879  N  N     . GLY C 1 173 ? 200.958 200.527 192.430 1.00 7.53   ? 173 GLY C N     1 
ATOM   4880  C  CA    . GLY C 1 173 ? 201.969 200.911 191.467 1.00 7.53   ? 173 GLY C CA    1 
ATOM   4881  C  C     . GLY C 1 173 ? 201.523 200.618 190.039 1.00 7.68   ? 173 GLY C C     1 
ATOM   4882  O  O     . GLY C 1 173 ? 201.856 201.358 189.122 1.00 7.81   ? 173 GLY C O     1 
ATOM   4883  N  N     . GLY C 1 174 ? 200.760 199.539 189.851 1.00 7.81   ? 174 GLY C N     1 
ATOM   4884  C  CA    . GLY C 1 174 ? 200.201 199.230 188.543 1.00 8.06   ? 174 GLY C CA    1 
ATOM   4885  C  C     . GLY C 1 174 ? 199.216 200.305 188.075 1.00 8.15   ? 174 GLY C C     1 
ATOM   4886  O  O     . GLY C 1 174 ? 199.198 200.671 186.904 1.00 8.59   ? 174 GLY C O     1 
ATOM   4887  N  N     . ILE C 1 175 ? 198.398 200.814 188.990 1.00 8.14   ? 175 ILE C N     1 
ATOM   4888  C  CA    . ILE C 1 175 ? 197.471 201.881 188.653 1.00 8.78   ? 175 ILE C CA    1 
ATOM   4889  C  C     . ILE C 1 175 ? 198.239 203.139 188.241 1.00 8.86   ? 175 ILE C C     1 
ATOM   4890  O  O     . ILE C 1 175 ? 197.884 203.798 187.260 1.00 9.06   ? 175 ILE C O     1 
ATOM   4891  C  CB    . ILE C 1 175 ? 196.516 202.159 189.826 1.00 9.43   ? 175 ILE C CB    1 
ATOM   4892  C  CG1   . ILE C 1 175 ? 195.587 200.965 190.062 1.00 10.16  ? 175 ILE C CG1   1 
ATOM   4893  C  CG2   . ILE C 1 175 ? 195.727 203.452 189.594 1.00 9.43   ? 175 ILE C CG2   1 
ATOM   4894  C  CD1   . ILE C 1 175 ? 194.986 200.936 191.442 1.00 10.83  ? 175 ILE C CD1   1 
ATOM   4895  N  N     . VAL C 1 176 ? 199.291 203.480 188.982 1.00 8.46   ? 176 VAL C N     1 
ATOM   4896  C  CA    . VAL C 1 176 ? 200.119 204.621 188.635 1.00 8.84   ? 176 VAL C CA    1 
ATOM   4897  C  C     . VAL C 1 176 ? 200.753 204.400 187.255 1.00 9.87   ? 176 VAL C C     1 
ATOM   4898  O  O     . VAL C 1 176 ? 200.785 205.314 186.430 1.00 9.50   ? 176 VAL C O     1 
ATOM   4899  C  CB    . VAL C 1 176 ? 201.189 204.862 189.712 1.00 8.72   ? 176 VAL C CB    1 
ATOM   4900  C  CG1   . VAL C 1 176 ? 202.262 205.843 189.228 1.00 9.16   ? 176 VAL C CG1   1 
ATOM   4901  C  CG2   . VAL C 1 176 ? 200.546 205.318 191.011 1.00 8.41   ? 176 VAL C CG2   1 
ATOM   4902  N  N     . GLY C 1 177 ? 201.265 203.189 187.012 1.00 9.51   ? 177 GLY C N     1 
ATOM   4903  C  CA    . GLY C 1 177 ? 201.957 202.907 185.775 1.00 10.47  ? 177 GLY C CA    1 
ATOM   4904  C  C     . GLY C 1 177 ? 201.061 203.074 184.546 1.00 11.15  ? 177 GLY C C     1 
ATOM   4905  O  O     . GLY C 1 177 ? 201.495 203.600 183.525 1.00 11.70  ? 177 GLY C O     1 
ATOM   4906  N  N     . MET C 1 178 ? 199.806 202.629 184.642 1.00 11.65  ? 178 MET C N     1 
ATOM   4907  C  CA    . MET C 1 178 ? 198.930 202.622 183.484 1.00 12.73  ? 178 MET C CA    1 
ATOM   4908  C  C     . MET C 1 178 ? 198.128 203.918 183.342 1.00 12.24  ? 178 MET C C     1 
ATOM   4909  O  O     . MET C 1 178 ? 197.342 204.029 182.414 1.00 14.02  ? 178 MET C O     1 
ATOM   4910  C  CB    . MET C 1 178 ? 197.997 201.411 183.548 1.00 13.75  ? 178 MET C CB    1 
ATOM   4911  C  CG    . MET C 1 178 ? 196.890 201.525 184.567 1.00 14.75  ? 178 MET C CG    1 
ATOM   4912  S  SD    . MET C 1 178 ? 195.999 199.948 184.679 1.00 17.41  ? 178 MET C SD    1 
ATOM   4913  C  CE    . MET C 1 178 ? 194.629 200.455 185.730 1.00 17.24  ? 178 MET C CE    1 
ATOM   4914  N  N     . THR C 1 179 ? 198.296 204.885 184.240 1.00 11.18  ? 179 THR C N     1 
ATOM   4915  C  CA    . THR C 1 179 ? 197.543 206.130 184.155 1.00 12.66  ? 179 THR C CA    1 
ATOM   4916  C  C     . THR C 1 179 ? 197.854 206.875 182.850 1.00 13.55  ? 179 THR C C     1 
ATOM   4917  O  O     . THR C 1 179 ? 196.944 207.254 182.112 1.00 11.51  ? 179 THR C O     1 
ATOM   4918  C  CB    . THR C 1 179 ? 197.811 207.016 185.367 1.00 11.97  ? 179 THR C CB    1 
ATOM   4919  O  OG1   . THR C 1 179 ? 197.282 206.371 186.524 1.00 11.91  ? 179 THR C OG1   1 
ATOM   4920  C  CG2   . THR C 1 179 ? 197.158 208.373 185.216 1.00 12.74  ? 179 THR C CG2   1 
ATOM   4921  N  N     . LEU C 1 180 ? 199.144 207.106 182.574 1.00 14.56  ? 180 LEU C N     1 
ATOM   4922  C  CA    . LEU C 1 180 ? 199.535 207.841 181.381 1.00 14.94  ? 180 LEU C CA    1 
ATOM   4923  C  C     . LEU C 1 180 ? 199.176 207.071 180.102 1.00 15.44  ? 180 LEU C C     1 
ATOM   4924  O  O     . LEU C 1 180 ? 198.615 207.670 179.178 1.00 17.48  ? 180 LEU C O     1 
ATOM   4925  C  CB    . LEU C 1 180 ? 201.020 208.189 181.411 1.00 16.61  ? 180 LEU C CB    1 
ATOM   4926  C  CG    . LEU C 1 180 ? 201.564 208.887 180.156 1.00 17.18  ? 180 LEU C CG    1 
ATOM   4927  C  CD1   . LEU C 1 180 ? 200.894 210.223 179.981 1.00 16.79  ? 180 LEU C CD1   1 
ATOM   4928  C  CD2   . LEU C 1 180 ? 203.079 209.008 180.214 1.00 18.78  ? 180 LEU C CD2   1 
ATOM   4929  N  N     . PRO C 1 181 ? 199.503 205.770 179.945 1.00 15.17  ? 181 PRO C N     1 
ATOM   4930  C  CA    . PRO C 1 181 ? 199.148 205.076 178.708 1.00 15.63  ? 181 PRO C CA    1 
ATOM   4931  C  C     . PRO C 1 181 ? 197.652 205.078 178.423 1.00 15.14  ? 181 PRO C C     1 
ATOM   4932  O  O     . PRO C 1 181 ? 197.237 205.212 177.272 1.00 16.20  ? 181 PRO C O     1 
ATOM   4933  C  CB    . PRO C 1 181 ? 199.654 203.639 178.859 1.00 16.13  ? 181 PRO C CB    1 
ATOM   4934  C  CG    . PRO C 1 181 ? 200.481 203.644 180.124 1.00 16.12  ? 181 PRO C CG    1 
ATOM   4935  C  CD    . PRO C 1 181 ? 200.296 204.932 180.868 1.00 16.07  ? 181 PRO C CD    1 
ATOM   4936  N  N     . ILE C 1 182 ? 196.823 204.911 179.461 1.00 13.92  ? 182 ILE C N     1 
ATOM   4937  C  CA    . ILE C 1 182 ? 195.390 204.907 179.240 1.00 13.12  ? 182 ILE C CA    1 
ATOM   4938  C  C     . ILE C 1 182 ? 194.926 206.312 178.856 1.00 12.27  ? 182 ILE C C     1 
ATOM   4939  O  O     . ILE C 1 182 ? 194.062 206.469 178.003 1.00 13.37  ? 182 ILE C O     1 
ATOM   4940  C  CB    . ILE C 1 182 ? 194.657 204.348 180.472 1.00 13.11  ? 182 ILE C CB    1 
ATOM   4941  C  CG1   . ILE C 1 182 ? 195.004 202.886 180.692 1.00 13.84  ? 182 ILE C CG1   1 
ATOM   4942  C  CG2   . ILE C 1 182 ? 193.154 204.532 180.344 1.00 12.48  ? 182 ILE C CG2   1 
ATOM   4943  C  CD1   . ILE C 1 182 ? 194.426 202.329 181.978 1.00 14.09  ? 182 ILE C CD1   1 
ATOM   4944  N  N     . ALA C 1 183 ? 195.493 207.339 179.491 1.00 12.19  ? 183 ALA C N     1 
ATOM   4945  C  CA    . ALA C 1 183 ? 195.225 208.719 179.095 1.00 12.72  ? 183 ALA C CA    1 
ATOM   4946  C  C     . ALA C 1 183 ? 195.606 208.934 177.629 1.00 12.92  ? 183 ALA C C     1 
ATOM   4947  O  O     . ALA C 1 183 ? 194.876 209.587 176.890 1.00 13.02  ? 183 ALA C O     1 
ATOM   4948  C  CB    . ALA C 1 183 ? 195.950 209.687 180.001 1.00 12.04  ? 183 ALA C CB    1 
ATOM   4949  N  N     . ARG C 1 184 ? 196.749 208.398 177.218 1.00 13.88  ? 184 ARG C N     1 
ATOM   4950  C  CA    . ARG C 1 184 ? 197.149 208.460 175.821 1.00 15.68  ? 184 ARG C CA    1 
ATOM   4951  C  C     . ARG C 1 184 ? 196.209 207.623 174.945 1.00 16.56  ? 184 ARG C C     1 
ATOM   4952  O  O     . ARG C 1 184 ? 195.893 208.030 173.835 1.00 18.66  ? 184 ARG C O     1 
ATOM   4953  C  CB    . ARG C 1 184 ? 198.593 207.977 175.664 1.00 16.46  ? 184 ARG C CB    1 
ATOM   4954  C  CG    . ARG C 1 184 ? 199.610 208.919 176.286 1.00 16.44  ? 184 ARG C CG    1 
ATOM   4955  C  CD    . ARG C 1 184 ? 200.965 208.226 176.354 1.00 17.54  ? 184 ARG C CD    1 
ATOM   4956  N  NE    . ARG C 1 184 ? 202.059 209.195 176.467 1.00 17.39  ? 184 ARG C NE    1 
ATOM   4957  C  CZ    . ARG C 1 184 ? 203.345 208.888 176.470 1.00 17.51  ? 184 ARG C CZ    1 
ATOM   4958  N  NH1   . ARG C 1 184 ? 203.746 207.631 176.440 1.00 17.49  ? 184 ARG C NH1   1 
ATOM   4959  N  NH2   . ARG C 1 184 ? 204.234 209.863 176.529 1.00 19.01  ? 184 ARG C NH2   1 
ATOM   4960  N  N     . ASP C 1 185 ? 195.780 206.456 175.428 1.00 16.23  ? 185 ASP C N     1 
ATOM   4961  C  CA    . ASP C 1 185 ? 194.843 205.626 174.686 1.00 17.21  ? 185 ASP C CA    1 
ATOM   4962  C  C     . ASP C 1 185 ? 193.538 206.375 174.411 1.00 16.06  ? 185 ASP C C     1 
ATOM   4963  O  O     . ASP C 1 185 ? 193.023 206.331 173.298 1.00 15.81  ? 185 ASP C O     1 
ATOM   4964  C  CB    . ASP C 1 185 ? 194.494 204.363 175.456 1.00 19.40  ? 185 ASP C CB    1 
ATOM   4965  C  CG    . ASP C 1 185 ? 195.450 203.208 175.274 1.00 22.46  ? 185 ASP C CG    1 
ATOM   4966  O  OD1   . ASP C 1 185 ? 196.371 203.354 174.440 1.00 23.84  ? 185 ASP C OD1   1 
ATOM   4967  O  OD2   . ASP C 1 185 ? 195.224 202.166 175.939 1.00 24.32  ? 185 ASP C OD2   1 
ATOM   4968  N  N     . LEU C 1 186 ? 192.997 207.060 175.432 1.00 14.29  ? 186 LEU C N     1 
ATOM   4969  C  CA    . LEU C 1 186 ? 191.673 207.654 175.351 1.00 13.29  ? 186 LEU C CA    1 
ATOM   4970  C  C     . LEU C 1 186 ? 191.718 209.126 174.961 1.00 13.69  ? 186 LEU C C     1 
ATOM   4971  O  O     . LEU C 1 186 ? 190.673 209.761 174.899 1.00 13.61  ? 186 LEU C O     1 
ATOM   4972  C  CB    . LEU C 1 186 ? 190.955 207.481 176.686 1.00 13.14  ? 186 LEU C CB    1 
ATOM   4973  C  CG    . LEU C 1 186 ? 190.883 206.052 177.223 1.00 12.61  ? 186 LEU C CG    1 
ATOM   4974  C  CD1   . LEU C 1 186 ? 190.090 206.012 178.516 1.00 12.77  ? 186 LEU C CD1   1 
ATOM   4975  C  CD2   . LEU C 1 186 ? 190.284 205.122 176.197 1.00 12.82  ? 186 LEU C CD2   1 
ATOM   4976  N  N     . ALA C 1 187 ? 192.912 209.671 174.698 1.00 15.08  ? 187 ALA C N     1 
ATOM   4977  C  CA    . ALA C 1 187 ? 193.044 211.071 174.321 1.00 17.11  ? 187 ALA C CA    1 
ATOM   4978  C  C     . ALA C 1 187 ? 192.264 211.389 173.045 1.00 18.78  ? 187 ALA C C     1 
ATOM   4979  O  O     . ALA C 1 187 ? 191.584 212.411 173.007 1.00 18.82  ? 187 ALA C O     1 
ATOM   4980  C  CB    . ALA C 1 187 ? 194.499 211.457 174.196 1.00 17.19  ? 187 ALA C CB    1 
ATOM   4981  N  N     . PRO C 1 188 ? 192.325 210.588 171.953 1.00 21.12  ? 188 PRO C N     1 
ATOM   4982  C  CA    . PRO C 1 188 ? 191.490 210.873 170.785 1.00 23.32  ? 188 PRO C CA    1 
ATOM   4983  C  C     . PRO C 1 188 ? 189.997 210.879 171.081 1.00 24.63  ? 188 PRO C C     1 
ATOM   4984  O  O     . PRO C 1 188 ? 189.234 211.595 170.444 1.00 28.12  ? 188 PRO C O     1 
ATOM   4985  C  CB    . PRO C 1 188 ? 191.854 209.767 169.788 1.00 24.36  ? 188 PRO C CB    1 
ATOM   4986  C  CG    . PRO C 1 188 ? 193.217 209.289 170.235 1.00 25.35  ? 188 PRO C CG    1 
ATOM   4987  C  CD    . PRO C 1 188 ? 193.216 209.435 171.736 1.00 22.63  ? 188 PRO C CD    1 
ATOM   4988  N  N     . ILE C 1 189 ? 189.571 210.085 172.059 1.00 24.51  ? 189 ILE C N     1 
ATOM   4989  C  CA    . ILE C 1 189 ? 188.164 209.970 172.399 1.00 23.81  ? 189 ILE C CA    1 
ATOM   4990  C  C     . ILE C 1 189 ? 187.742 211.176 173.241 1.00 19.64  ? 189 ILE C C     1 
ATOM   4991  O  O     . ILE C 1 189 ? 186.566 211.503 173.285 1.00 20.86  ? 189 ILE C O     1 
ATOM   4992  C  CB    . ILE C 1 189 ? 187.910 208.639 173.134 1.00 29.19  ? 189 ILE C CB    1 
ATOM   4993  C  CG1   . ILE C 1 189 ? 188.383 207.452 172.333 1.00 35.04  ? 189 ILE C CG1   1 
ATOM   4994  C  CG2   . ILE C 1 189 ? 186.442 208.489 173.510 1.00 31.19  ? 189 ILE C CG2   1 
ATOM   4995  C  CD1   . ILE C 1 189 ? 188.015 206.112 172.941 1.00 36.47  ? 189 ILE C CD1   1 
ATOM   4996  N  N     . GLY C 1 190 ? 188.700 211.849 173.887 1.00 16.21  ? 190 GLY C N     1 
ATOM   4997  C  CA    . GLY C 1 190 ? 188.402 212.961 174.774 1.00 13.55  ? 190 GLY C CA    1 
ATOM   4998  C  C     . GLY C 1 190 ? 188.002 212.504 176.179 1.00 11.42  ? 190 GLY C C     1 
ATOM   4999  O  O     . GLY C 1 190 ? 187.151 213.135 176.807 1.00 11.79  ? 190 GLY C O     1 
ATOM   5000  N  N     . ILE C 1 191 ? 188.644 211.438 176.674 1.00 10.12  ? 191 ILE C N     1 
ATOM   5001  C  CA    . ILE C 1 191 ? 188.424 210.981 178.035 1.00 9.54   ? 191 ILE C CA    1 
ATOM   5002  C  C     . ILE C 1 191 ? 189.701 211.226 178.828 1.00 8.75   ? 191 ILE C C     1 
ATOM   5003  O  O     . ILE C 1 191 ? 190.738 210.636 178.525 1.00 9.05   ? 191 ILE C O     1 
ATOM   5004  C  CB    . ILE C 1 191 ? 188.017 209.499 178.067 1.00 9.85   ? 191 ILE C CB    1 
ATOM   5005  C  CG1   . ILE C 1 191 ? 186.701 209.278 177.327 1.00 10.11  ? 191 ILE C CG1   1 
ATOM   5006  C  CG2   . ILE C 1 191 ? 187.928 208.989 179.501 1.00 9.29   ? 191 ILE C CG2   1 
ATOM   5007  C  CD1   . ILE C 1 191 ? 186.357 207.820 177.130 1.00 10.14  ? 191 ILE C CD1   1 
ATOM   5008  N  N     . ARG C 1 192 ? 189.609 212.068 179.852 1.00 8.34   ? 192 ARG C N     1 
ATOM   5009  C  CA    . ARG C 1 192 ? 190.742 212.328 180.724 1.00 8.33   ? 192 ARG C CA    1 
ATOM   5010  C  C     . ARG C 1 192 ? 190.865 211.206 181.752 1.00 7.98   ? 192 ARG C C     1 
ATOM   5011  O  O     . ARG C 1 192 ? 189.875 210.741 182.309 1.00 8.05   ? 192 ARG C O     1 
ATOM   5012  C  CB    . ARG C 1 192 ? 190.601 213.675 181.426 1.00 8.53   ? 192 ARG C CB    1 
ATOM   5013  C  CG    . ARG C 1 192 ? 190.673 214.852 180.467 1.00 8.71   ? 192 ARG C CG    1 
ATOM   5014  C  CD    . ARG C 1 192 ? 190.820 216.171 181.196 1.00 8.87   ? 192 ARG C CD    1 
ATOM   5015  N  NE    . ARG C 1 192 ? 189.586 216.561 181.887 1.00 8.90   ? 192 ARG C NE    1 
ATOM   5016  C  CZ    . ARG C 1 192 ? 189.440 216.697 183.190 1.00 9.00   ? 192 ARG C CZ    1 
ATOM   5017  N  NH1   . ARG C 1 192 ? 190.435 216.433 184.027 1.00 8.56   ? 192 ARG C NH1   1 
ATOM   5018  N  NH2   . ARG C 1 192 ? 188.285 217.107 183.674 1.00 9.13   ? 192 ARG C NH2   1 
ATOM   5019  N  N     . VAL C 1 193 ? 192.111 210.799 182.010 1.00 8.00   ? 193 VAL C N     1 
ATOM   5020  C  CA    . VAL C 1 193 ? 192.396 209.772 182.993 1.00 8.05   ? 193 VAL C CA    1 
ATOM   5021  C  C     . VAL C 1 193 ? 193.338 210.362 184.029 1.00 7.81   ? 193 VAL C C     1 
ATOM   5022  O  O     . VAL C 1 193 ? 194.419 210.828 183.688 1.00 8.02   ? 193 VAL C O     1 
ATOM   5023  C  CB    . VAL C 1 193 ? 192.995 208.507 182.356 1.00 8.32   ? 193 VAL C CB    1 
ATOM   5024  C  CG1   . VAL C 1 193 ? 193.201 207.411 183.382 1.00 8.56   ? 193 VAL C CG1   1 
ATOM   5025  C  CG2   . VAL C 1 193 ? 192.120 208.007 181.221 1.00 8.67   ? 193 VAL C CG2   1 
ATOM   5026  N  N     . MET C 1 194 ? 192.909 210.332 185.288 1.00 7.33   ? 194 MET C N     1 
ATOM   5027  C  CA    . MET C 1 194 ? 193.656 210.923 186.377 1.00 7.43   ? 194 MET C CA    1 
ATOM   5028  C  C     . MET C 1 194 ? 193.683 209.938 187.536 1.00 7.23   ? 194 MET C C     1 
ATOM   5029  O  O     . MET C 1 194 ? 192.818 209.077 187.652 1.00 7.69   ? 194 MET C O     1 
ATOM   5030  C  CB    . MET C 1 194 ? 193.010 212.239 186.845 1.00 7.85   ? 194 MET C CB    1 
ATOM   5031  C  CG    . MET C 1 194 ? 193.392 213.458 186.039 1.00 8.20   ? 194 MET C CG    1 
ATOM   5032  S  SD    . MET C 1 194 ? 195.159 213.823 186.104 1.00 8.96   ? 194 MET C SD    1 
ATOM   5033  C  CE    . MET C 1 194 ? 195.331 214.371 187.813 1.00 8.63   ? 194 MET C CE    1 
ATOM   5034  N  N     . THR C 1 195 ? 194.694 210.070 188.388 1.00 7.09   ? 195 THR C N     1 
ATOM   5035  C  CA    . THR C 1 195 ? 194.868 209.187 189.526 1.00 7.34   ? 195 THR C CA    1 
ATOM   5036  C  C     . THR C 1 195 ? 195.149 210.022 190.769 1.00 6.84   ? 195 THR C C     1 
ATOM   5037  O  O     . THR C 1 195 ? 195.978 210.923 190.729 1.00 7.12   ? 195 THR C O     1 
ATOM   5038  C  CB    . THR C 1 195 ? 195.981 208.173 189.265 1.00 7.55   ? 195 THR C CB    1 
ATOM   5039  O  OG1   . THR C 1 195 ? 195.588 207.313 188.196 1.00 8.13   ? 195 THR C OG1   1 
ATOM   5040  C  CG2   . THR C 1 195 ? 196.244 207.318 190.487 1.00 7.69   ? 195 THR C CG2   1 
ATOM   5041  N  N     . ILE C 1 196 ? 194.488 209.668 191.869 1.00 6.58   ? 196 ILE C N     1 
ATOM   5042  C  CA    . ILE C 1 196 ? 194.758 210.242 193.170 1.00 6.93   ? 196 ILE C CA    1 
ATOM   5043  C  C     . ILE C 1 196 ? 195.451 209.195 194.023 1.00 7.23   ? 196 ILE C C     1 
ATOM   5044  O  O     . ILE C 1 196 ? 195.035 208.037 194.053 1.00 7.93   ? 196 ILE C O     1 
ATOM   5045  C  CB    . ILE C 1 196 ? 193.462 210.734 193.846 1.00 7.29   ? 196 ILE C CB    1 
ATOM   5046  C  CG1   . ILE C 1 196 ? 192.767 211.778 192.998 1.00 7.45   ? 196 ILE C CG1   1 
ATOM   5047  C  CG2   . ILE C 1 196 ? 193.747 211.258 195.258 1.00 7.15   ? 196 ILE C CG2   1 
ATOM   5048  C  CD1   . ILE C 1 196 ? 191.387 212.148 193.506 1.00 7.82   ? 196 ILE C CD1   1 
ATOM   5049  N  N     . ALA C 1 197 ? 196.529 209.602 194.692 1.00 7.46   ? 197 ALA C N     1 
ATOM   5050  C  CA    . ALA C 1 197 ? 197.265 208.721 195.581 1.00 8.01   ? 197 ALA C CA    1 
ATOM   5051  C  C     . ALA C 1 197 ? 197.063 209.212 197.011 1.00 8.66   ? 197 ALA C C     1 
ATOM   5052  O  O     . ALA C 1 197 ? 197.829 210.027 197.521 1.00 9.20   ? 197 ALA C O     1 
ATOM   5053  C  CB    . ALA C 1 197 ? 198.737 208.698 195.215 1.00 7.56   ? 197 ALA C CB    1 
ATOM   5054  N  N     . PRO C 1 198 ? 196.005 208.758 197.704 1.00 9.48   ? 198 PRO C N     1 
ATOM   5055  C  CA    . PRO C 1 198 ? 195.762 209.228 199.065 1.00 9.64   ? 198 PRO C CA    1 
ATOM   5056  C  C     . PRO C 1 198 ? 196.806 208.700 200.032 1.00 10.07  ? 198 PRO C C     1 
ATOM   5057  O  O     . PRO C 1 198 ? 197.377 207.623 199.827 1.00 9.88   ? 198 PRO C O     1 
ATOM   5058  C  CB    . PRO C 1 198 ? 194.375 208.686 199.414 1.00 9.95   ? 198 PRO C CB    1 
ATOM   5059  C  CG    . PRO C 1 198 ? 193.771 208.220 198.112 1.00 10.38  ? 198 PRO C CG    1 
ATOM   5060  C  CD    . PRO C 1 198 ? 194.944 207.873 197.202 1.00 10.13  ? 198 PRO C CD    1 
ATOM   5061  N  N     . GLY C 1 199 ? 197.049 209.466 201.090 1.00 10.90  ? 199 GLY C N     1 
ATOM   5062  C  CA    . GLY C 1 199 ? 197.898 209.006 202.167 1.00 12.04  ? 199 GLY C CA    1 
ATOM   5063  C  C     . GLY C 1 199 ? 197.049 208.283 203.209 1.00 13.35  ? 199 GLY C C     1 
ATOM   5064  O  O     . GLY C 1 199 ? 196.301 207.366 202.881 1.00 14.29  ? 199 GLY C O     1 
ATOM   5065  N  N     . LEU C 1 200 ? 197.203 208.677 204.474 1.00 14.14  ? 200 LEU C N     1 
ATOM   5066  C  CA    . LEU C 1 200 ? 196.448 208.090 205.566 1.00 14.85  ? 200 LEU C CA    1 
ATOM   5067  C  C     . LEU C 1 200 ? 195.130 208.844 205.703 1.00 14.45  ? 200 LEU C C     1 
ATOM   5068  O  O     . LEU C 1 200 ? 195.129 210.029 206.009 1.00 14.99  ? 200 LEU C O     1 
ATOM   5069  C  CB    . LEU C 1 200 ? 197.266 208.180 206.848 1.00 16.18  ? 200 LEU C CB    1 
ATOM   5070  C  CG    . LEU C 1 200 ? 198.650 207.532 206.796 1.00 18.45  ? 200 LEU C CG    1 
ATOM   5071  C  CD1   . LEU C 1 200 ? 199.378 207.709 208.127 1.00 20.29  ? 200 LEU C CD1   1 
ATOM   5072  C  CD2   . LEU C 1 200 ? 198.541 206.061 206.452 1.00 19.12  ? 200 LEU C CD2   1 
ATOM   5073  N  N     . PHE C 1 201 ? 194.021 208.152 205.445 1.00 13.98  ? 201 PHE C N     1 
ATOM   5074  C  CA    . PHE C 1 201 ? 192.701 208.747 205.510 1.00 14.97  ? 201 PHE C CA    1 
ATOM   5075  C  C     . PHE C 1 201 ? 191.872 208.042 206.576 1.00 16.55  ? 201 PHE C C     1 
ATOM   5076  O  O     . PHE C 1 201 ? 192.013 206.844 206.816 1.00 17.28  ? 201 PHE C O     1 
ATOM   5077  C  CB    . PHE C 1 201 ? 191.988 208.667 204.155 1.00 15.16  ? 201 PHE C CB    1 
ATOM   5078  C  CG    . PHE C 1 201 ? 192.238 209.890 203.305 1.00 14.26  ? 201 PHE C CG    1 
ATOM   5079  C  CD1   . PHE C 1 201 ? 193.486 210.105 202.721 1.00 13.79  ? 201 PHE C CD1   1 
ATOM   5080  C  CD2   . PHE C 1 201 ? 191.229 210.811 203.085 1.00 14.36  ? 201 PHE C CD2   1 
ATOM   5081  C  CE1   . PHE C 1 201 ? 193.701 211.225 201.929 1.00 13.30  ? 201 PHE C CE1   1 
ATOM   5082  C  CE2   . PHE C 1 201 ? 191.464 211.944 202.321 1.00 14.09  ? 201 PHE C CE2   1 
ATOM   5083  C  CZ    . PHE C 1 201 ? 192.702 212.157 201.755 1.00 14.19  ? 201 PHE C CZ    1 
ATOM   5084  N  N     . GLY C 1 202 ? 190.955 208.806 207.166 1.00 18.54  ? 202 GLY C N     1 
ATOM   5085  C  CA    . GLY C 1 202 ? 190.091 208.297 208.211 1.00 20.55  ? 202 GLY C CA    1 
ATOM   5086  C  C     . GLY C 1 202 ? 188.962 207.458 207.619 1.00 23.03  ? 202 GLY C C     1 
ATOM   5087  O  O     . GLY C 1 202 ? 187.794 207.682 207.916 1.00 27.06  ? 202 GLY C O     1 
ATOM   5088  N  N     . THR C 1 203 ? 189.320 206.460 206.808 1.00 25.34  ? 203 THR C N     1 
ATOM   5089  C  CA    . THR C 1 203 ? 188.368 205.474 206.332 1.00 28.84  ? 203 THR C CA    1 
ATOM   5090  C  C     . THR C 1 203 ? 188.059 204.499 207.457 1.00 33.82  ? 203 THR C C     1 
ATOM   5091  O  O     . THR C 1 203 ? 188.803 204.408 208.433 1.00 32.41  ? 203 THR C O     1 
ATOM   5092  C  CB    . THR C 1 203 ? 188.934 204.746 205.119 1.00 29.88  ? 203 THR C CB    1 
ATOM   5093  O  OG1   . THR C 1 203 ? 190.204 204.190 205.465 1.00 31.75  ? 203 THR C OG1   1 
ATOM   5094  C  CG2   . THR C 1 203 ? 189.051 205.686 203.935 1.00 31.01  ? 203 THR C CG2   1 
ATOM   5095  N  N     . PRO C 1 204 ? 186.929 203.761 207.379 1.00 43.04  ? 204 PRO C N     1 
ATOM   5096  C  CA    . PRO C 1 204 ? 186.597 202.787 208.421 1.00 45.54  ? 204 PRO C CA    1 
ATOM   5097  C  C     . PRO C 1 204 ? 187.689 201.759 208.701 1.00 45.24  ? 204 PRO C C     1 
ATOM   5098  O  O     . PRO C 1 204 ? 187.823 201.306 209.830 1.00 46.75  ? 204 PRO C O     1 
ATOM   5099  C  CB    . PRO C 1 204 ? 185.324 202.127 207.898 1.00 47.69  ? 204 PRO C CB    1 
ATOM   5100  C  CG    . PRO C 1 204 ? 184.703 203.191 207.031 1.00 48.32  ? 204 PRO C CG    1 
ATOM   5101  C  CD    . PRO C 1 204 ? 185.882 203.858 206.345 1.00 46.12  ? 204 PRO C CD    1 
ATOM   5102  N  N     . LEU C 1 205 ? 188.490 201.427 207.686 1.00 45.52  ? 205 LEU C N     1 
ATOM   5103  C  CA    . LEU C 1 205 ? 189.578 200.479 207.861 1.00 47.03  ? 205 LEU C CA    1 
ATOM   5104  C  C     . LEU C 1 205 ? 190.626 201.036 208.823 1.00 45.41  ? 205 LEU C C     1 
ATOM   5105  O  O     . LEU C 1 205 ? 191.161 200.294 209.644 1.00 47.04  ? 205 LEU C O     1 
ATOM   5106  C  CB    . LEU C 1 205 ? 190.185 200.137 206.500 1.00 53.74  ? 205 LEU C CB    1 
ATOM   5107  C  CG    . LEU C 1 205 ? 191.262 199.045 206.486 1.00 58.78  ? 205 LEU C CG    1 
ATOM   5108  C  CD1   . LEU C 1 205 ? 191.106 198.129 205.279 1.00 60.74  ? 205 LEU C CD1   1 
ATOM   5109  C  CD2   . LEU C 1 205 ? 192.657 199.639 206.481 1.00 60.61  ? 205 LEU C CD2   1 
ATOM   5110  N  N     . LEU C 1 206 ? 190.919 202.340 208.737 1.00 38.39  ? 206 LEU C N     1 
ATOM   5111  C  CA    . LEU C 1 206 ? 191.903 202.938 209.628 1.00 34.47  ? 206 LEU C CA    1 
ATOM   5112  C  C     . LEU C 1 206 ? 191.264 203.297 210.969 1.00 32.69  ? 206 LEU C C     1 
ATOM   5113  O  O     . LEU C 1 206 ? 191.897 203.128 212.013 1.00 30.04  ? 206 LEU C O     1 
ATOM   5114  C  CB    . LEU C 1 206 ? 192.571 204.161 209.006 1.00 35.08  ? 206 LEU C CB    1 
ATOM   5115  C  CG    . LEU C 1 206 ? 193.933 203.921 208.353 1.00 35.00  ? 206 LEU C CG    1 
ATOM   5116  C  CD1   . LEU C 1 206 ? 193.734 203.028 207.149 1.00 39.31  ? 206 LEU C CD1   1 
ATOM   5117  C  CD2   . LEU C 1 206 ? 194.586 205.236 207.938 1.00 34.22  ? 206 LEU C CD2   1 
ATOM   5118  N  N     . THR C 1 207 ? 190.038 203.828 210.948 1.00 32.24  ? 207 THR C N     1 
ATOM   5119  C  CA    . THR C 1 207 ? 189.417 204.312 212.172 1.00 34.67  ? 207 THR C CA    1 
ATOM   5120  C  C     . THR C 1 207 ? 189.042 203.162 213.105 1.00 34.68  ? 207 THR C C     1 
ATOM   5121  O  O     . THR C 1 207 ? 188.812 203.395 214.286 1.00 38.06  ? 207 THR C O     1 
ATOM   5122  C  CB    . THR C 1 207 ? 188.199 205.177 211.857 1.00 35.22  ? 207 THR C CB    1 
ATOM   5123  O  OG1   . THR C 1 207 ? 187.284 204.407 211.086 1.00 35.42  ? 207 THR C OG1   1 
ATOM   5124  C  CG2   . THR C 1 207 ? 188.580 206.422 211.081 1.00 37.12  ? 207 THR C CG2   1 
ATOM   5125  N  N     . SER C 1 208 ? 188.977 201.933 212.588 1.00 35.17  ? 208 SER C N     1 
ATOM   5126  C  CA    . SER C 1 208 ? 188.685 200.765 213.406 1.00 36.80  ? 208 SER C CA    1 
ATOM   5127  C  C     . SER C 1 208 ? 189.889 200.345 214.251 1.00 36.49  ? 208 SER C C     1 
ATOM   5128  O  O     . SER C 1 208 ? 189.754 199.490 215.129 1.00 38.18  ? 208 SER C O     1 
ATOM   5129  C  CB    . SER C 1 208 ? 188.219 199.628 212.536 1.00 36.34  ? 208 SER C CB    1 
ATOM   5130  O  OG    . SER C 1 208 ? 189.295 199.071 211.790 1.00 38.30  ? 208 SER C OG    1 
ATOM   5131  N  N     . LEU C 1 209 ? 191.069 200.900 213.964 1.00 34.25  ? 209 LEU C N     1 
ATOM   5132  C  CA    . LEU C 1 209 ? 192.276 200.534 214.695 1.00 31.90  ? 209 LEU C CA    1 
ATOM   5133  C  C     . LEU C 1 209 ? 192.183 201.086 216.114 1.00 28.77  ? 209 LEU C C     1 
ATOM   5134  O  O     . LEU C 1 209 ? 191.430 202.021 216.376 1.00 31.52  ? 209 LEU C O     1 
ATOM   5135  C  CB    . LEU C 1 209 ? 193.525 201.053 213.987 1.00 31.95  ? 209 LEU C CB    1 
ATOM   5136  C  CG    . LEU C 1 209 ? 193.794 200.476 212.596 1.00 31.71  ? 209 LEU C CG    1 
ATOM   5137  C  CD1   . LEU C 1 209 ? 194.957 201.156 211.915 1.00 32.56  ? 209 LEU C CD1   1 
ATOM   5138  C  CD2   . LEU C 1 209 ? 194.033 198.986 212.694 1.00 33.07  ? 209 LEU C CD2   1 
ATOM   5139  N  N     . PRO C 1 210 ? 192.959 200.543 217.074 1.00 28.92  ? 210 PRO C N     1 
ATOM   5140  C  CA    . PRO C 1 210 ? 193.015 201.120 218.414 1.00 29.94  ? 210 PRO C CA    1 
ATOM   5141  C  C     . PRO C 1 210 ? 193.393 202.596 218.381 1.00 31.52  ? 210 PRO C C     1 
ATOM   5142  O  O     . PRO C 1 210 ? 194.202 203.023 217.562 1.00 32.72  ? 210 PRO C O     1 
ATOM   5143  C  CB    . PRO C 1 210 ? 194.080 200.274 219.132 1.00 29.33  ? 210 PRO C CB    1 
ATOM   5144  C  CG    . PRO C 1 210 ? 194.097 198.979 218.370 1.00 30.04  ? 210 PRO C CG    1 
ATOM   5145  C  CD    . PRO C 1 210 ? 193.808 199.348 216.931 1.00 27.85  ? 210 PRO C CD    1 
ATOM   5146  N  N     . GLU C 1 211 ? 192.839 203.357 219.320 1.00 32.95  ? 211 GLU C N     1 
ATOM   5147  C  CA    . GLU C 1 211 ? 193.033 204.796 219.358 1.00 34.95  ? 211 GLU C CA    1 
ATOM   5148  C  C     . GLU C 1 211 ? 194.508 205.158 219.521 1.00 31.33  ? 211 GLU C C     1 
ATOM   5149  O  O     . GLU C 1 211 ? 194.935 206.216 219.083 1.00 29.40  ? 211 GLU C O     1 
ATOM   5150  C  CB    . GLU C 1 211 ? 192.168 205.434 220.445 1.00 41.32  ? 211 GLU C CB    1 
ATOM   5151  C  CG    . GLU C 1 211 ? 192.643 205.215 221.877 1.00 50.13  ? 211 GLU C CG    1 
ATOM   5152  C  CD    . GLU C 1 211 ? 192.026 206.202 222.867 1.00 60.18  ? 211 GLU C CD    1 
ATOM   5153  O  OE1   . GLU C 1 211 ? 192.777 206.774 223.698 1.00 62.73  ? 211 GLU C OE1   1 
ATOM   5154  O  OE2   . GLU C 1 211 ? 190.792 206.420 222.798 1.00 61.80  ? 211 GLU C OE2   1 
ATOM   5155  N  N     . LYS C 1 212 ? 195.288 204.317 220.201 1.00 29.31  ? 212 LYS C N     1 
ATOM   5156  C  CA    . LYS C 1 212 ? 196.728 204.524 220.291 1.00 30.03  ? 212 LYS C CA    1 
ATOM   5157  C  C     . LYS C 1 212 ? 197.376 204.506 218.901 1.00 25.90  ? 212 LYS C C     1 
ATOM   5158  O  O     . LYS C 1 212 ? 198.243 205.313 218.613 1.00 25.85  ? 212 LYS C O     1 
ATOM   5159  C  CB    . LYS C 1 212 ? 197.340 203.445 221.184 1.00 34.91  ? 212 LYS C CB    1 
ATOM   5160  C  CG    . LYS C 1 212 ? 198.845 203.484 221.278 1.00 41.86  ? 212 LYS C CG    1 
ATOM   5161  C  CD    . LYS C 1 212 ? 199.402 202.266 222.004 1.00 48.69  ? 212 LYS C CD    1 
ATOM   5162  C  CE    . LYS C 1 212 ? 198.717 201.975 223.317 1.00 52.91  ? 212 LYS C CE    1 
ATOM   5163  N  NZ    . LYS C 1 212 ? 198.624 203.159 224.179 1.00 53.38  ? 212 LYS C NZ    1 
ATOM   5164  N  N     . VAL C 1 213 ? 196.969 203.564 218.054 1.00 23.72  ? 213 VAL C N     1 
ATOM   5165  C  CA    . VAL C 1 213 ? 197.503 203.469 216.706 1.00 23.41  ? 213 VAL C CA    1 
ATOM   5166  C  C     . VAL C 1 213 ? 197.020 204.655 215.873 1.00 22.06  ? 213 VAL C C     1 
ATOM   5167  O  O     . VAL C 1 213 ? 197.788 205.233 215.108 1.00 21.69  ? 213 VAL C O     1 
ATOM   5168  C  CB    . VAL C 1 213 ? 197.109 202.125 216.071 1.00 23.40  ? 213 VAL C CB    1 
ATOM   5169  C  CG1   . VAL C 1 213 ? 197.411 202.092 214.578 1.00 23.94  ? 213 VAL C CG1   1 
ATOM   5170  C  CG2   . VAL C 1 213 ? 197.777 200.970 216.799 1.00 23.59  ? 213 VAL C CG2   1 
ATOM   5171  N  N     . CYS C 1 214 ? 195.743 205.010 216.003 1.00 22.20  ? 214 CYS C N     1 
ATOM   5172  C  CA    . CYS C 1 214 ? 195.184 206.131 215.255 1.00 23.43  ? 214 CYS C CA    1 
ATOM   5173  C  C     . CYS C 1 214 ? 195.885 207.447 215.607 1.00 21.73  ? 214 CYS C C     1 
ATOM   5174  O  O     . CYS C 1 214 ? 196.175 208.253 214.729 1.00 20.33  ? 214 CYS C O     1 
ATOM   5175  C  CB    . CYS C 1 214 ? 193.684 206.249 215.499 1.00 25.90  ? 214 CYS C CB    1 
ATOM   5176  S  SG    . CYS C 1 214 ? 192.709 205.090 214.509 1.00 30.89  ? 214 CYS C SG    1 
ATOM   5177  N  N     . ASN C 1 215 ? 196.157 207.663 216.895 1.00 21.59  ? 215 ASN C N     1 
ATOM   5178  C  CA    . ASN C 1 215 ? 196.844 208.863 217.338 1.00 22.31  ? 215 ASN C CA    1 
ATOM   5179  C  C     . ASN C 1 215 ? 198.260 208.917 216.770 1.00 20.10  ? 215 ASN C C     1 
ATOM   5180  O  O     . ASN C 1 215 ? 198.725 209.975 216.362 1.00 19.73  ? 215 ASN C O     1 
ATOM   5181  C  CB    . ASN C 1 215 ? 196.856 208.957 218.856 1.00 25.60  ? 215 ASN C CB    1 
ATOM   5182  C  CG    . ASN C 1 215 ? 195.486 209.239 219.428 1.00 30.01  ? 215 ASN C CG    1 
ATOM   5183  O  OD1   . ASN C 1 215 ? 194.513 209.438 218.691 1.00 31.15  ? 215 ASN C OD1   1 
ATOM   5184  N  ND2   . ASN C 1 215 ? 195.387 209.237 220.749 1.00 32.86  ? 215 ASN C ND2   1 
ATOM   5185  N  N     . PHE C 1 216 ? 198.956 207.783 216.771 1.00 17.93  ? 216 PHE C N     1 
ATOM   5186  C  CA    . PHE C 1 216 ? 200.304 207.736 216.237 1.00 16.85  ? 216 PHE C CA    1 
ATOM   5187  C  C     . PHE C 1 216 ? 200.300 208.027 214.737 1.00 16.07  ? 216 PHE C C     1 
ATOM   5188  O  O     . PHE C 1 216 ? 201.146 208.779 214.251 1.00 17.04  ? 216 PHE C O     1 
ATOM   5189  C  CB    . PHE C 1 216 ? 200.959 206.386 216.532 1.00 16.25  ? 216 PHE C CB    1 
ATOM   5190  C  CG    . PHE C 1 216 ? 202.210 206.146 215.710 1.00 15.44  ? 216 PHE C CG    1 
ATOM   5191  C  CD1   . PHE C 1 216 ? 203.366 206.895 215.928 1.00 15.16  ? 216 PHE C CD1   1 
ATOM   5192  C  CD2   . PHE C 1 216 ? 202.211 205.194 214.702 1.00 15.59  ? 216 PHE C CD2   1 
ATOM   5193  C  CE1   . PHE C 1 216 ? 204.491 206.685 215.154 1.00 15.48  ? 216 PHE C CE1   1 
ATOM   5194  C  CE2   . PHE C 1 216 ? 203.352 204.967 213.949 1.00 15.82  ? 216 PHE C CE2   1 
ATOM   5195  C  CZ    . PHE C 1 216 ? 204.480 205.724 214.167 1.00 15.70  ? 216 PHE C CZ    1 
ATOM   5196  N  N     . LEU C 1 217 ? 199.379 207.412 213.995 1.00 16.13  ? 217 LEU C N     1 
ATOM   5197  C  CA    . LEU C 1 217 ? 199.319 207.608 212.553 1.00 16.67  ? 217 LEU C CA    1 
ATOM   5198  C  C     . LEU C 1 217 ? 199.035 209.069 212.222 1.00 15.97  ? 217 LEU C C     1 
ATOM   5199  O  O     . LEU C 1 217 ? 199.624 209.621 211.282 1.00 16.68  ? 217 LEU C O     1 
ATOM   5200  C  CB    . LEU C 1 217 ? 198.271 206.696 211.919 1.00 17.82  ? 217 LEU C CB    1 
ATOM   5201  C  CG    . LEU C 1 217 ? 198.649 205.217 211.824 1.00 19.78  ? 217 LEU C CG    1 
ATOM   5202  C  CD1   . LEU C 1 217 ? 197.444 204.402 211.373 1.00 21.75  ? 217 LEU C CD1   1 
ATOM   5203  C  CD2   . LEU C 1 217 ? 199.826 205.046 210.865 1.00 19.87  ? 217 LEU C CD2   1 
ATOM   5204  N  N     . ALA C 1 218 ? 198.131 209.696 212.993 1.00 15.24  ? 218 ALA C N     1 
ATOM   5205  C  CA    . ALA C 1 218 ? 197.829 211.106 212.792 1.00 16.24  ? 218 ALA C CA    1 
ATOM   5206  C  C     . ALA C 1 218 ? 199.075 211.961 213.005 1.00 15.79  ? 218 ALA C C     1 
ATOM   5207  O  O     . ALA C 1 218 ? 199.311 212.893 212.235 1.00 16.17  ? 218 ALA C O     1 
ATOM   5208  C  CB    . ALA C 1 218 ? 196.702 211.551 213.698 1.00 15.84  ? 218 ALA C CB    1 
ATOM   5209  N  N     . SER C 1 219 ? 199.868 211.630 214.031 1.00 15.75  ? 219 SER C N     1 
ATOM   5210  C  CA    . SER C 1 219 ? 201.075 212.379 214.340 1.00 15.67  ? 219 SER C CA    1 
ATOM   5211  C  C     . SER C 1 219 ? 202.149 212.192 213.269 1.00 15.92  ? 219 SER C C     1 
ATOM   5212  O  O     . SER C 1 219 ? 203.070 213.000 213.188 1.00 17.59  ? 219 SER C O     1 
ATOM   5213  C  CB    . SER C 1 219 ? 201.616 211.997 215.699 1.00 16.31  ? 219 SER C CB    1 
ATOM   5214  O  OG    . SER C 1 219 ? 202.205 210.702 215.680 1.00 16.38  ? 219 SER C OG    1 
ATOM   5215  N  N     . GLN C 1 220 ? 202.051 211.138 212.452 1.00 15.98  ? 220 GLN C N     1 
ATOM   5216  C  CA    . GLN C 1 220 ? 203.029 210.918 211.400 1.00 16.44  ? 220 GLN C CA    1 
ATOM   5217  C  C     . GLN C 1 220 ? 202.810 211.853 210.203 1.00 14.10  ? 220 GLN C C     1 
ATOM   5218  O  O     . GLN C 1 220 ? 203.730 212.075 209.436 1.00 14.76  ? 220 GLN C O     1 
ATOM   5219  C  CB    . GLN C 1 220 ? 202.988 209.469 210.931 1.00 18.23  ? 220 GLN C CB    1 
ATOM   5220  C  CG    . GLN C 1 220 ? 203.553 208.489 211.949 1.00 20.80  ? 220 GLN C CG    1 
ATOM   5221  C  CD    . GLN C 1 220 ? 205.008 208.752 212.247 1.00 23.74  ? 220 GLN C CD    1 
ATOM   5222  O  OE1   . GLN C 1 220 ? 205.351 209.487 213.177 1.00 25.92  ? 220 GLN C OE1   1 
ATOM   5223  N  NE2   . GLN C 1 220 ? 205.882 208.102 211.489 1.00 26.12  ? 220 GLN C NE2   1 
ATOM   5224  N  N     . VAL C 1 221 ? 201.608 212.391 210.034 1.00 12.65  ? 221 VAL C N     1 
ATOM   5225  C  CA    . VAL C 1 221 ? 201.354 213.311 208.939 1.00 12.42  ? 221 VAL C CA    1 
ATOM   5226  C  C     . VAL C 1 221 ? 201.955 214.667 209.303 1.00 12.44  ? 221 VAL C C     1 
ATOM   5227  O  O     . VAL C 1 221 ? 201.618 215.230 210.340 1.00 12.83  ? 221 VAL C O     1 
ATOM   5228  C  CB    . VAL C 1 221 ? 199.852 213.435 208.648 1.00 12.47  ? 221 VAL C CB    1 
ATOM   5229  C  CG1   . VAL C 1 221 ? 199.612 214.269 207.382 1.00 12.13  ? 221 VAL C CG1   1 
ATOM   5230  C  CG2   . VAL C 1 221 ? 199.192 212.056 208.562 1.00 11.90  ? 221 VAL C CG2   1 
ATOM   5231  N  N     . PRO C 1 222 ? 202.895 215.212 208.500 1.00 12.19  ? 222 PRO C N     1 
ATOM   5232  C  CA    . PRO C 1 222 ? 203.519 216.494 208.826 1.00 12.07  ? 222 PRO C CA    1 
ATOM   5233  C  C     . PRO C 1 222 ? 202.521 217.622 209.059 1.00 11.52  ? 222 PRO C C     1 
ATOM   5234  O  O     . PRO C 1 222 ? 202.509 218.200 210.137 1.00 11.88  ? 222 PRO C O     1 
ATOM   5235  C  CB    . PRO C 1 222 ? 204.433 216.775 207.629 1.00 11.98  ? 222 PRO C CB    1 
ATOM   5236  C  CG    . PRO C 1 222 ? 204.747 215.394 207.105 1.00 12.38  ? 222 PRO C CG    1 
ATOM   5237  C  CD    . PRO C 1 222 ? 203.470 214.597 207.293 1.00 12.19  ? 222 PRO C CD    1 
ATOM   5238  N  N     . PHE C 1 223 ? 201.690 217.931 208.063 1.00 11.26  ? 223 PHE C N     1 
ATOM   5239  C  CA    . PHE C 1 223 ? 200.647 218.929 208.262 1.00 11.14  ? 223 PHE C CA    1 
ATOM   5240  C  C     . PHE C 1 223 ? 199.565 218.779 207.200 1.00 11.14  ? 223 PHE C C     1 
ATOM   5241  O  O     . PHE C 1 223 ? 199.870 218.721 206.014 1.00 10.94  ? 223 PHE C O     1 
ATOM   5242  C  CB    . PHE C 1 223 ? 201.184 220.369 208.276 1.00 11.15  ? 223 PHE C CB    1 
ATOM   5243  C  CG    . PHE C 1 223 ? 200.086 221.383 208.567 1.00 11.04  ? 223 PHE C CG    1 
ATOM   5244  C  CD1   . PHE C 1 223 ? 199.663 221.601 209.872 1.00 11.00  ? 223 PHE C CD1   1 
ATOM   5245  C  CD2   . PHE C 1 223 ? 199.437 222.070 207.545 1.00 10.98  ? 223 PHE C CD2   1 
ATOM   5246  C  CE1   . PHE C 1 223 ? 198.611 222.466 210.143 1.00 11.31  ? 223 PHE C CE1   1 
ATOM   5247  C  CE2   . PHE C 1 223 ? 198.365 222.904 207.819 1.00 11.17  ? 223 PHE C CE2   1 
ATOM   5248  C  CZ    . PHE C 1 223 ? 197.945 223.089 209.114 1.00 11.57  ? 223 PHE C CZ    1 
ATOM   5249  N  N     . PRO C 1 224 ? 198.263 218.738 207.571 1.00 12.09  ? 224 PRO C N     1 
ATOM   5250  C  CA    . PRO C 1 224 ? 197.796 218.750 208.958 1.00 12.22  ? 224 PRO C CA    1 
ATOM   5251  C  C     . PRO C 1 224 ? 198.025 217.423 209.667 1.00 12.34  ? 224 PRO C C     1 
ATOM   5252  O  O     . PRO C 1 224 ? 197.884 216.376 209.048 1.00 12.57  ? 224 PRO C O     1 
ATOM   5253  C  CB    . PRO C 1 224 ? 196.308 219.113 208.830 1.00 13.06  ? 224 PRO C CB    1 
ATOM   5254  C  CG    . PRO C 1 224 ? 195.921 218.606 207.487 1.00 12.73  ? 224 PRO C CG    1 
ATOM   5255  C  CD    . PRO C 1 224 ? 197.155 218.715 206.619 1.00 12.64  ? 224 PRO C CD    1 
ATOM   5256  N  N     . SER C 1 225 ? 198.376 217.474 210.959 1.00 13.19  ? 225 SER C N     1 
ATOM   5257  C  CA    . SER C 1 225 ? 198.744 216.279 211.699 1.00 14.42  ? 225 SER C CA    1 
ATOM   5258  C  C     . SER C 1 225 ? 197.484 215.537 212.133 1.00 13.87  ? 225 SER C C     1 
ATOM   5259  O  O     . SER C 1 225 ? 197.165 215.435 213.313 1.00 15.32  ? 225 SER C O     1 
ATOM   5260  C  CB    . SER C 1 225 ? 199.635 216.604 212.864 1.00 14.84  ? 225 SER C CB    1 
ATOM   5261  O  OG    . SER C 1 225 ? 200.867 217.137 212.417 1.00 15.57  ? 225 SER C OG    1 
ATOM   5262  N  N     . ARG C 1 226 ? 196.793 214.976 211.148 1.00 13.58  ? 226 ARG C N     1 
ATOM   5263  C  CA    . ARG C 1 226 ? 195.585 214.216 211.380 1.00 14.21  ? 226 ARG C CA    1 
ATOM   5264  C  C     . ARG C 1 226 ? 195.395 213.281 210.195 1.00 13.56  ? 226 ARG C C     1 
ATOM   5265  O  O     . ARG C 1 226 ? 195.992 213.459 209.148 1.00 13.78  ? 226 ARG C O     1 
ATOM   5266  C  CB    . ARG C 1 226 ? 194.389 215.153 211.568 1.00 14.71  ? 226 ARG C CB    1 
ATOM   5267  C  CG    . ARG C 1 226 ? 194.142 216.084 210.388 1.00 15.68  ? 226 ARG C CG    1 
ATOM   5268  C  CD    . ARG C 1 226 ? 192.721 216.571 210.345 1.00 16.23  ? 226 ARG C CD    1 
ATOM   5269  N  NE    . ARG C 1 226 ? 192.533 217.616 209.339 1.00 16.46  ? 226 ARG C NE    1 
ATOM   5270  C  CZ    . ARG C 1 226 ? 192.348 217.418 208.043 1.00 17.68  ? 226 ARG C CZ    1 
ATOM   5271  N  NH1   . ARG C 1 226 ? 192.330 216.196 207.530 1.00 18.01  ? 226 ARG C NH1   1 
ATOM   5272  N  NH2   . ARG C 1 226 ? 192.157 218.449 207.237 1.00 17.11  ? 226 ARG C NH2   1 
ATOM   5273  N  N     . LEU C 1 227 ? 194.507 212.312 210.361 1.00 14.01  ? 227 LEU C N     1 
ATOM   5274  C  CA    . LEU C 1 227 ? 194.104 211.480 209.245 1.00 14.14  ? 227 LEU C CA    1 
ATOM   5275  C  C     . LEU C 1 227 ? 193.376 212.341 208.217 1.00 13.26  ? 227 LEU C C     1 
ATOM   5276  O  O     . LEU C 1 227 ? 192.635 213.259 208.557 1.00 13.63  ? 227 LEU C O     1 
ATOM   5277  C  CB    . LEU C 1 227 ? 193.236 210.331 209.740 1.00 14.79  ? 227 LEU C CB    1 
ATOM   5278  C  CG    . LEU C 1 227 ? 193.926 209.308 210.645 1.00 16.48  ? 227 LEU C CG    1 
ATOM   5279  C  CD1   . LEU C 1 227 ? 192.972 208.155 210.929 1.00 17.79  ? 227 LEU C CD1   1 
ATOM   5280  C  CD2   . LEU C 1 227 ? 195.233 208.809 210.059 1.00 16.58  ? 227 LEU C CD2   1 
ATOM   5281  N  N     . GLY C 1 228 ? 193.532 211.980 206.950 1.00 13.45  ? 228 GLY C N     1 
ATOM   5282  C  CA    . GLY C 1 228 ? 192.806 212.646 205.890 1.00 13.36  ? 228 GLY C CA    1 
ATOM   5283  C  C     . GLY C 1 228 ? 191.295 212.465 206.047 1.00 14.44  ? 228 GLY C C     1 
ATOM   5284  O  O     . GLY C 1 228 ? 190.807 211.366 206.299 1.00 13.70  ? 228 GLY C O     1 
ATOM   5285  N  N     . ASP C 1 229 ? 190.551 213.553 205.871 1.00 15.20  ? 229 ASP C N     1 
ATOM   5286  C  CA    . ASP C 1 229 ? 189.101 213.492 205.859 1.00 16.63  ? 229 ASP C CA    1 
ATOM   5287  C  C     . ASP C 1 229 ? 188.645 213.006 204.483 1.00 15.18  ? 229 ASP C C     1 
ATOM   5288  O  O     . ASP C 1 229 ? 189.083 213.528 203.455 1.00 13.46  ? 229 ASP C O     1 
ATOM   5289  C  CB    . ASP C 1 229 ? 188.506 214.851 206.155 1.00 19.71  ? 229 ASP C CB    1 
ATOM   5290  C  CG    . ASP C 1 229 ? 187.036 214.798 206.534 1.00 25.34  ? 229 ASP C CG    1 
ATOM   5291  O  OD1   . ASP C 1 229 ? 186.710 215.306 207.631 1.00 31.07  ? 229 ASP C OD1   1 
ATOM   5292  O  OD2   . ASP C 1 229 ? 186.226 214.238 205.755 1.00 27.32  ? 229 ASP C OD2   1 
ATOM   5293  N  N     . PRO C 1 230 ? 187.779 211.975 204.397 1.00 14.28  ? 230 PRO C N     1 
ATOM   5294  C  CA    . PRO C 1 230 ? 187.292 211.520 203.096 1.00 13.83  ? 230 PRO C CA    1 
ATOM   5295  C  C     . PRO C 1 230 ? 186.671 212.615 202.233 1.00 12.25  ? 230 PRO C C     1 
ATOM   5296  O  O     . PRO C 1 230 ? 186.736 212.538 201.013 1.00 12.05  ? 230 PRO C O     1 
ATOM   5297  C  CB    . PRO C 1 230 ? 186.292 210.420 203.449 1.00 14.07  ? 230 PRO C CB    1 
ATOM   5298  C  CG    . PRO C 1 230 ? 186.757 209.928 204.795 1.00 14.49  ? 230 PRO C CG    1 
ATOM   5299  C  CD    . PRO C 1 230 ? 187.280 211.152 205.512 1.00 14.86  ? 230 PRO C CD    1 
ATOM   5300  N  N     . ALA C 1 231 ? 186.079 213.634 202.863 1.00 12.01  ? 231 ALA C N     1 
ATOM   5301  C  CA    . ALA C 1 231 ? 185.565 214.789 202.145 1.00 12.40  ? 231 ALA C CA    1 
ATOM   5302  C  C     . ALA C 1 231 ? 186.673 215.528 201.388 1.00 12.21  ? 231 ALA C C     1 
ATOM   5303  O  O     . ALA C 1 231 ? 186.422 216.076 200.321 1.00 11.89  ? 231 ALA C O     1 
ATOM   5304  C  CB    . ALA C 1 231 ? 184.857 215.719 203.094 1.00 12.93  ? 231 ALA C CB    1 
ATOM   5305  N  N     . GLU C 1 232 ? 187.898 215.508 201.917 1.00 12.18  ? 232 GLU C N     1 
ATOM   5306  C  CA    . GLU C 1 232 ? 189.030 216.122 201.238 1.00 12.43  ? 232 GLU C CA    1 
ATOM   5307  C  C     . GLU C 1 232 ? 189.369 215.368 199.956 1.00 10.72  ? 232 GLU C C     1 
ATOM   5308  O  O     . GLU C 1 232 ? 189.730 215.981 198.952 1.00 10.51  ? 232 GLU C O     1 
ATOM   5309  C  CB    . GLU C 1 232 ? 190.244 216.190 202.161 1.00 14.79  ? 232 GLU C CB    1 
ATOM   5310  C  CG    . GLU C 1 232 ? 190.140 217.336 203.156 1.00 17.56  ? 232 GLU C CG    1 
ATOM   5311  C  CD    . GLU C 1 232 ? 190.802 217.034 204.473 1.00 20.20  ? 232 GLU C CD    1 
ATOM   5312  O  OE1   . GLU C 1 232 ? 191.607 216.085 204.560 1.00 20.82  ? 232 GLU C OE1   1 
ATOM   5313  O  OE2   . GLU C 1 232 ? 190.498 217.777 205.437 1.00 26.04  ? 232 GLU C OE2   1 
ATOM   5314  N  N     . TYR C 1 233 ? 189.243 214.042 199.987 1.00 9.43   ? 233 TYR C N     1 
ATOM   5315  C  CA    . TYR C 1 233 ? 189.401 213.258 198.772 1.00 9.11   ? 233 TYR C CA    1 
ATOM   5316  C  C     . TYR C 1 233 ? 188.319 213.656 197.771 1.00 8.03   ? 233 TYR C C     1 
ATOM   5317  O  O     . TYR C 1 233 ? 188.592 213.801 196.580 1.00 7.57   ? 233 TYR C O     1 
ATOM   5318  C  CB    . TYR C 1 233 ? 189.373 211.765 199.093 1.00 9.31   ? 233 TYR C CB    1 
ATOM   5319  C  CG    . TYR C 1 233 ? 189.374 210.868 197.871 1.00 9.85   ? 233 TYR C CG    1 
ATOM   5320  C  CD1   . TYR C 1 233 ? 190.561 210.352 197.385 1.00 10.55  ? 233 TYR C CD1   1 
ATOM   5321  C  CD2   . TYR C 1 233 ? 188.194 210.496 197.237 1.00 10.37  ? 233 TYR C CD2   1 
ATOM   5322  C  CE1   . TYR C 1 233 ? 190.586 209.506 196.285 1.00 11.10  ? 233 TYR C CE1   1 
ATOM   5323  C  CE2   . TYR C 1 233 ? 188.204 209.656 196.138 1.00 10.97  ? 233 TYR C CE2   1 
ATOM   5324  C  CZ    . TYR C 1 233 ? 189.399 209.167 195.658 1.00 11.17  ? 233 TYR C CZ    1 
ATOM   5325  O  OH    . TYR C 1 233 ? 189.404 208.348 194.564 1.00 11.41  ? 233 TYR C OH    1 
ATOM   5326  N  N     . ALA C 1 234 ? 187.071 213.774 198.249 1.00 7.82   ? 234 ALA C N     1 
ATOM   5327  C  CA    . ALA C 1 234 ? 185.955 214.127 197.381 1.00 7.70   ? 234 ALA C CA    1 
ATOM   5328  C  C     . ALA C 1 234 ? 186.173 215.499 196.748 1.00 7.80   ? 234 ALA C C     1 
ATOM   5329  O  O     . ALA C 1 234 ? 185.854 215.709 195.584 1.00 7.84   ? 234 ALA C O     1 
ATOM   5330  C  CB    . ALA C 1 234 ? 184.647 214.082 198.163 1.00 7.66   ? 234 ALA C CB    1 
ATOM   5331  N  N     . HIS C 1 235 ? 186.703 216.445 197.526 1.00 8.20   ? 235 HIS C N     1 
ATOM   5332  C  CA    . HIS C 1 235 ? 186.982 217.776 197.011 1.00 8.43   ? 235 HIS C CA    1 
ATOM   5333  C  C     . HIS C 1 235 ? 187.978 217.722 195.859 1.00 7.64   ? 235 HIS C C     1 
ATOM   5334  O  O     . HIS C 1 235 ? 187.801 218.411 194.857 1.00 7.22   ? 235 HIS C O     1 
ATOM   5335  C  CB    . HIS C 1 235 ? 187.500 218.678 198.140 1.00 9.66   ? 235 HIS C CB    1 
ATOM   5336  C  CG    . HIS C 1 235 ? 187.857 220.052 197.692 1.00 11.20  ? 235 HIS C CG    1 
ATOM   5337  N  ND1   . HIS C 1 235 ? 189.110 220.348 197.188 1.00 12.11  ? 235 HIS C ND1   1 
ATOM   5338  C  CD2   . HIS C 1 235 ? 187.145 221.196 197.654 1.00 12.62  ? 235 HIS C CD2   1 
ATOM   5339  C  CE1   . HIS C 1 235 ? 189.139 221.633 196.825 1.00 12.98  ? 235 HIS C CE1   1 
ATOM   5340  N  NE2   . HIS C 1 235 ? 187.960 222.171 197.120 1.00 12.70  ? 235 HIS C NE2   1 
ATOM   5341  N  N     . LEU C 1 236 ? 189.037 216.916 195.997 1.00 6.90   ? 236 LEU C N     1 
ATOM   5342  C  CA    . LEU C 1 236 ? 190.023 216.795 194.944 1.00 6.64   ? 236 LEU C CA    1 
ATOM   5343  C  C     . LEU C 1 236 ? 189.403 216.156 193.702 1.00 6.75   ? 236 LEU C C     1 
ATOM   5344  O  O     . LEU C 1 236 ? 189.742 216.526 192.585 1.00 6.77   ? 236 LEU C O     1 
ATOM   5345  C  CB    . LEU C 1 236 ? 191.240 216.001 195.424 1.00 6.79   ? 236 LEU C CB    1 
ATOM   5346  C  CG    . LEU C 1 236 ? 192.350 215.783 194.393 1.00 6.80   ? 236 LEU C CG    1 
ATOM   5347  C  CD1   . LEU C 1 236 ? 192.837 217.121 193.856 1.00 6.84   ? 236 LEU C CD1   1 
ATOM   5348  C  CD2   . LEU C 1 236 ? 193.501 214.988 195.004 1.00 6.75   ? 236 LEU C CD2   1 
ATOM   5349  N  N     . VAL C 1 237 ? 188.517 215.169 193.891 1.00 7.00   ? 237 VAL C N     1 
ATOM   5350  C  CA    . VAL C 1 237 ? 187.843 214.545 192.772 1.00 7.06   ? 237 VAL C CA    1 
ATOM   5351  C  C     . VAL C 1 237 ? 187.073 215.596 191.976 1.00 7.31   ? 237 VAL C C     1 
ATOM   5352  O  O     . VAL C 1 237 ? 187.130 215.626 190.752 1.00 7.28   ? 237 VAL C O     1 
ATOM   5353  C  CB    . VAL C 1 237 ? 186.932 213.393 193.231 1.00 7.11   ? 237 VAL C CB    1 
ATOM   5354  C  CG1   . VAL C 1 237 ? 185.965 212.987 192.131 1.00 7.04   ? 237 VAL C CG1   1 
ATOM   5355  C  CG2   . VAL C 1 237 ? 187.733 212.198 193.706 1.00 6.84   ? 237 VAL C CG2   1 
ATOM   5356  N  N     . GLN C 1 238 ? 186.321 216.452 192.666 1.00 8.21   ? 238 GLN C N     1 
ATOM   5357  C  CA    . GLN C 1 238 ? 185.577 217.495 191.992 1.00 9.09   ? 238 GLN C CA    1 
ATOM   5358  C  C     . GLN C 1 238 ? 186.503 218.469 191.253 1.00 8.90   ? 238 GLN C C     1 
ATOM   5359  O  O     . GLN C 1 238 ? 186.219 218.870 190.130 1.00 9.05   ? 238 GLN C O     1 
ATOM   5360  C  CB    . GLN C 1 238 ? 184.693 218.253 192.975 1.00 10.29  ? 238 GLN C CB    1 
ATOM   5361  C  CG    . GLN C 1 238 ? 183.830 219.308 192.293 1.00 11.53  ? 238 GLN C CG    1 
ATOM   5362  C  CD    . GLN C 1 238 ? 182.853 219.969 193.236 1.00 13.24  ? 238 GLN C CD    1 
ATOM   5363  O  OE1   . GLN C 1 238 ? 182.751 219.599 194.415 1.00 14.91  ? 238 GLN C OE1   1 
ATOM   5364  N  NE2   . GLN C 1 238 ? 182.149 220.967 192.724 1.00 14.91  ? 238 GLN C NE2   1 
ATOM   5365  N  N     . ALA C 1 239 ? 187.624 218.836 191.883 1.00 8.97   ? 239 ALA C N     1 
ATOM   5366  C  CA    . ALA C 1 239 ? 188.598 219.712 191.244 1.00 9.20   ? 239 ALA C CA    1 
ATOM   5367  C  C     . ALA C 1 239 ? 189.111 219.095 189.944 1.00 9.38   ? 239 ALA C C     1 
ATOM   5368  O  O     . ALA C 1 239 ? 189.257 219.798 188.946 1.00 9.13   ? 239 ALA C O     1 
ATOM   5369  C  CB    . ALA C 1 239 ? 189.732 220.019 192.189 1.00 9.42   ? 239 ALA C CB    1 
ATOM   5370  N  N     . ILE C 1 240 ? 189.377 217.781 189.951 1.00 8.90   ? 240 ILE C N     1 
ATOM   5371  C  CA    . ILE C 1 240 ? 189.852 217.109 188.759 1.00 9.40   ? 240 ILE C CA    1 
ATOM   5372  C  C     . ILE C 1 240 ? 188.781 217.129 187.671 1.00 9.19   ? 240 ILE C C     1 
ATOM   5373  O  O     . ILE C 1 240 ? 189.079 217.376 186.509 1.00 9.63   ? 240 ILE C O     1 
ATOM   5374  C  CB    . ILE C 1 240 ? 190.316 215.676 189.081 1.00 9.29   ? 240 ILE C CB    1 
ATOM   5375  C  CG1   . ILE C 1 240 ? 191.547 215.677 189.943 1.00 9.65   ? 240 ILE C CG1   1 
ATOM   5376  C  CG2   . ILE C 1 240 ? 190.532 214.881 187.792 1.00 9.30   ? 240 ILE C CG2   1 
ATOM   5377  C  CD1   . ILE C 1 240 ? 191.900 214.320 190.518 1.00 9.76   ? 240 ILE C CD1   1 
ATOM   5378  N  N     . ILE C 1 241 ? 187.528 216.875 188.055 1.00 9.83   ? 241 ILE C N     1 
ATOM   5379  C  CA    . ILE C 1 241 ? 186.442 216.877 187.090 1.00 10.33  ? 241 ILE C CA    1 
ATOM   5380  C  C     . ILE C 1 241 ? 186.299 218.260 186.463 1.00 11.11  ? 241 ILE C C     1 
ATOM   5381  O  O     . ILE C 1 241 ? 186.116 218.378 185.254 1.00 11.29  ? 241 ILE C O     1 
ATOM   5382  C  CB    . ILE C 1 241 ? 185.132 216.409 187.746 1.00 10.60  ? 241 ILE C CB    1 
ATOM   5383  C  CG1   . ILE C 1 241 ? 185.235 214.958 188.195 1.00 10.79  ? 241 ILE C CG1   1 
ATOM   5384  C  CG2   . ILE C 1 241 ? 183.947 216.604 186.799 1.00 10.58  ? 241 ILE C CG2   1 
ATOM   5385  C  CD1   . ILE C 1 241 ? 184.182 214.580 189.210 1.00 11.06  ? 241 ILE C CD1   1 
ATOM   5386  N  N     . GLU C 1 242 ? 186.376 219.313 187.278 1.00 12.39  ? 242 GLU C N     1 
ATOM   5387  C  CA    . GLU C 1 242 ? 186.134 220.661 186.792 1.00 13.82  ? 242 GLU C CA    1 
ATOM   5388  C  C     . GLU C 1 242 ? 187.306 221.200 185.967 1.00 13.72  ? 242 GLU C C     1 
ATOM   5389  O  O     . GLU C 1 242 ? 187.100 222.045 185.107 1.00 15.13  ? 242 GLU C O     1 
ATOM   5390  C  CB    . GLU C 1 242 ? 185.877 221.602 187.969 1.00 16.90  ? 242 GLU C CB    1 
ATOM   5391  C  CG    . GLU C 1 242 ? 184.617 221.274 188.763 1.00 20.33  ? 242 GLU C CG    1 
ATOM   5392  C  CD    . GLU C 1 242 ? 184.469 222.177 189.979 1.00 25.31  ? 242 GLU C CD    1 
ATOM   5393  O  OE1   . GLU C 1 242 ? 183.309 222.310 190.429 1.00 28.15  ? 242 GLU C OE1   1 
ATOM   5394  O  OE2   . GLU C 1 242 ? 185.482 222.738 190.490 1.00 28.03  ? 242 GLU C OE2   1 
ATOM   5395  N  N     . ASN C 1 243 ? 188.532 220.732 186.214 1.00 12.93  ? 243 ASN C N     1 
ATOM   5396  C  CA    . ASN C 1 243 ? 189.702 221.293 185.557 1.00 12.72  ? 243 ASN C CA    1 
ATOM   5397  C  C     . ASN C 1 243 ? 189.967 220.524 184.268 1.00 13.21  ? 243 ASN C C     1 
ATOM   5398  O  O     . ASN C 1 243 ? 190.355 219.359 184.322 1.00 12.95  ? 243 ASN C O     1 
ATOM   5399  C  CB    . ASN C 1 243 ? 190.928 221.247 186.459 1.00 12.66  ? 243 ASN C CB    1 
ATOM   5400  C  CG    . ASN C 1 243 ? 192.047 222.141 185.972 1.00 12.36  ? 243 ASN C CG    1 
ATOM   5401  O  OD1   . ASN C 1 243 ? 192.509 222.024 184.830 1.00 12.45  ? 243 ASN C OD1   1 
ATOM   5402  N  ND2   . ASN C 1 243 ? 192.489 223.058 186.810 1.00 12.05  ? 243 ASN C ND2   1 
ATOM   5403  N  N     . PRO C 1 244 ? 189.774 221.130 183.079 1.00 13.61  ? 244 PRO C N     1 
ATOM   5404  C  CA    . PRO C 1 244 ? 189.909 220.389 181.828 1.00 13.56  ? 244 PRO C CA    1 
ATOM   5405  C  C     . PRO C 1 244 ? 191.327 220.012 181.425 1.00 13.21  ? 244 PRO C C     1 
ATOM   5406  O  O     . PRO C 1 244 ? 191.498 219.240 180.494 1.00 14.03  ? 244 PRO C O     1 
ATOM   5407  C  CB    . PRO C 1 244 ? 189.281 221.317 180.778 1.00 14.23  ? 244 PRO C CB    1 
ATOM   5408  C  CG    . PRO C 1 244 ? 188.676 222.454 181.559 1.00 14.93  ? 244 PRO C CG    1 
ATOM   5409  C  CD    . PRO C 1 244 ? 189.399 222.536 182.870 1.00 14.17  ? 244 PRO C CD    1 
ATOM   5410  N  N     . PHE C 1 245 ? 192.344 220.553 182.104 1.00 11.96  ? 245 PHE C N     1 
ATOM   5411  C  CA    . PHE C 1 245 ? 193.711 220.381 181.646 1.00 11.71  ? 245 PHE C CA    1 
ATOM   5412  C  C     . PHE C 1 245 ? 194.513 219.424 182.519 1.00 10.69  ? 245 PHE C C     1 
ATOM   5413  O  O     . PHE C 1 245 ? 195.691 219.208 182.256 1.00 11.59  ? 245 PHE C O     1 
ATOM   5414  C  CB    . PHE C 1 245 ? 194.401 221.739 181.562 1.00 12.86  ? 245 PHE C CB    1 
ATOM   5415  C  CG    . PHE C 1 245 ? 195.449 221.781 180.470 1.00 14.04  ? 245 PHE C CG    1 
ATOM   5416  C  CD1   . PHE C 1 245 ? 195.089 221.674 179.130 1.00 15.18  ? 245 PHE C CD1   1 
ATOM   5417  C  CD2   . PHE C 1 245 ? 196.785 221.955 180.787 1.00 14.83  ? 245 PHE C CD2   1 
ATOM   5418  C  CE1   . PHE C 1 245 ? 196.051 221.725 178.131 1.00 15.21  ? 245 PHE C CE1   1 
ATOM   5419  C  CE2   . PHE C 1 245 ? 197.743 222.048 179.784 1.00 15.52  ? 245 PHE C CE2   1 
ATOM   5420  C  CZ    . PHE C 1 245 ? 197.383 221.898 178.462 1.00 15.62  ? 245 PHE C CZ    1 
ATOM   5421  N  N     . LEU C 1 246 ? 193.868 218.825 183.523 1.00 10.02  ? 246 LEU C N     1 
ATOM   5422  C  CA    . LEU C 1 246 ? 194.475 217.775 184.332 1.00 10.02  ? 246 LEU C CA    1 
ATOM   5423  C  C     . LEU C 1 246 ? 194.273 216.441 183.630 1.00 9.62   ? 246 LEU C C     1 
ATOM   5424  O  O     . LEU C 1 246 ? 193.143 215.991 183.485 1.00 9.74   ? 246 LEU C O     1 
ATOM   5425  C  CB    . LEU C 1 246 ? 193.873 217.746 185.734 1.00 9.85   ? 246 LEU C CB    1 
ATOM   5426  C  CG    . LEU C 1 246 ? 194.392 218.763 186.748 1.00 9.63   ? 246 LEU C CG    1 
ATOM   5427  C  CD1   . LEU C 1 246 ? 193.507 218.784 187.965 1.00 9.71   ? 246 LEU C CD1   1 
ATOM   5428  C  CD2   . LEU C 1 246 ? 195.830 218.426 187.139 1.00 9.70   ? 246 LEU C CD2   1 
ATOM   5429  N  N     . ASN C 1 247 ? 195.368 215.796 183.231 1.00 9.05   ? 247 ASN C N     1 
ATOM   5430  C  CA    . ASN C 1 247 ? 195.283 214.540 182.525 1.00 8.72   ? 247 ASN C CA    1 
ATOM   5431  C  C     . ASN C 1 247 ? 196.588 213.763 182.678 1.00 9.00   ? 247 ASN C C     1 
ATOM   5432  O  O     . ASN C 1 247 ? 197.673 214.331 182.662 1.00 9.28   ? 247 ASN C O     1 
ATOM   5433  C  CB    . ASN C 1 247 ? 194.961 214.774 181.056 1.00 8.50   ? 247 ASN C CB    1 
ATOM   5434  C  CG    . ASN C 1 247 ? 194.425 213.548 180.366 1.00 8.18   ? 247 ASN C CG    1 
ATOM   5435  O  OD1   . ASN C 1 247 ? 194.066 212.569 181.021 1.00 8.30   ? 247 ASN C OD1   1 
ATOM   5436  N  ND2   . ASN C 1 247 ? 194.336 213.611 179.052 1.00 8.30   ? 247 ASN C ND2   1 
ATOM   5437  N  N     . GLY C 1 248 ? 196.464 212.449 182.833 1.00 8.82   ? 248 GLY C N     1 
ATOM   5438  C  CA    . GLY C 1 248 ? 197.609 211.557 182.852 1.00 9.66   ? 248 GLY C CA    1 
ATOM   5439  C  C     . GLY C 1 248 ? 198.533 211.779 184.041 1.00 9.53   ? 248 GLY C C     1 
ATOM   5440  O  O     . GLY C 1 248 ? 199.708 211.463 183.929 1.00 9.77   ? 248 GLY C O     1 
ATOM   5441  N  N     . GLU C 1 249 ? 198.008 212.282 185.159 1.00 9.73   ? 249 GLU C N     1 
ATOM   5442  C  CA    . GLU C 1 249 ? 198.831 212.688 186.288 1.00 10.58  ? 249 GLU C CA    1 
ATOM   5443  C  C     . GLU C 1 249 ? 198.353 211.997 187.560 1.00 9.82   ? 249 GLU C C     1 
ATOM   5444  O  O     . GLU C 1 249 ? 197.185 211.682 187.700 1.00 9.82   ? 249 GLU C O     1 
ATOM   5445  C  CB    . GLU C 1 249 ? 198.780 214.217 186.414 1.00 12.47  ? 249 GLU C CB    1 
ATOM   5446  C  CG    . GLU C 1 249 ? 199.288 214.796 187.730 1.00 15.00  ? 249 GLU C CG    1 
ATOM   5447  C  CD    . GLU C 1 249 ? 200.779 214.558 188.007 1.00 18.14  ? 249 GLU C CD    1 
ATOM   5448  O  OE1   . GLU C 1 249 ? 201.505 213.993 187.135 1.00 21.63  ? 249 GLU C OE1   1 
ATOM   5449  O  OE2   . GLU C 1 249 ? 201.208 214.987 189.100 1.00 19.15  ? 249 GLU C OE2   1 
ATOM   5450  N  N     . VAL C 1 250 ? 199.294 211.771 188.476 1.00 9.53   ? 250 VAL C N     1 
ATOM   5451  C  CA    . VAL C 1 250 ? 199.010 211.224 189.783 1.00 9.36   ? 250 VAL C CA    1 
ATOM   5452  C  C     . VAL C 1 250 ? 199.193 212.330 190.806 1.00 8.88   ? 250 VAL C C     1 
ATOM   5453  O  O     . VAL C 1 250 ? 200.256 212.920 190.887 1.00 9.57   ? 250 VAL C O     1 
ATOM   5454  C  CB    . VAL C 1 250 ? 199.932 210.033 190.110 1.00 10.35  ? 250 VAL C CB    1 
ATOM   5455  C  CG1   . VAL C 1 250 ? 199.631 209.479 191.497 1.00 10.41  ? 250 VAL C CG1   1 
ATOM   5456  C  CG2   . VAL C 1 250 ? 199.818 208.940 189.062 1.00 10.97  ? 250 VAL C CG2   1 
ATOM   5457  N  N     . ILE C 1 251 ? 198.154 212.586 191.603 1.00 8.45   ? 251 ILE C N     1 
ATOM   5458  C  CA    . ILE C 1 251 ? 198.208 213.607 192.633 1.00 8.23   ? 251 ILE C CA    1 
ATOM   5459  C  C     . ILE C 1 251 ? 198.258 212.931 193.995 1.00 8.49   ? 251 ILE C C     1 
ATOM   5460  O  O     . ILE C 1 251 ? 197.335 212.217 194.366 1.00 8.49   ? 251 ILE C O     1 
ATOM   5461  C  CB    . ILE C 1 251 ? 197.006 214.559 192.544 1.00 8.44   ? 251 ILE C CB    1 
ATOM   5462  C  CG1   . ILE C 1 251 ? 196.961 215.270 191.207 1.00 8.28   ? 251 ILE C CG1   1 
ATOM   5463  C  CG2   . ILE C 1 251 ? 197.025 215.547 193.708 1.00 8.40   ? 251 ILE C CG2   1 
ATOM   5464  C  CD1   . ILE C 1 251 ? 195.726 216.110 190.985 1.00 8.42   ? 251 ILE C CD1   1 
ATOM   5465  N  N     . ARG C 1 252 ? 199.334 213.186 194.739 1.00 8.91   ? 252 ARG C N     1 
ATOM   5466  C  CA    . ARG C 1 252 ? 199.455 212.720 196.103 1.00 9.56   ? 252 ARG C CA    1 
ATOM   5467  C  C     . ARG C 1 252 ? 198.629 213.615 197.015 1.00 9.35   ? 252 ARG C C     1 
ATOM   5468  O  O     . ARG C 1 252 ? 198.819 214.830 197.051 1.00 9.79   ? 252 ARG C O     1 
ATOM   5469  C  CB    . ARG C 1 252 ? 200.916 212.720 196.544 1.00 10.60  ? 252 ARG C CB    1 
ATOM   5470  C  CG    . ARG C 1 252 ? 201.794 211.721 195.803 1.00 11.78  ? 252 ARG C CG    1 
ATOM   5471  C  CD    . ARG C 1 252 ? 203.217 211.789 196.303 1.00 12.90  ? 252 ARG C CD    1 
ATOM   5472  N  NE    . ARG C 1 252 ? 203.316 211.447 197.723 1.00 13.61  ? 252 ARG C NE    1 
ATOM   5473  C  CZ    . ARG C 1 252 ? 204.138 210.533 198.241 1.00 15.05  ? 252 ARG C CZ    1 
ATOM   5474  N  NH1   . ARG C 1 252 ? 205.048 209.932 197.500 1.00 14.67  ? 252 ARG C NH1   1 
ATOM   5475  N  NH2   . ARG C 1 252 ? 204.068 210.243 199.530 1.00 14.91  ? 252 ARG C NH2   1 
ATOM   5476  N  N     . LEU C 1 253 ? 197.696 213.001 197.739 1.00 9.16   ? 253 LEU C N     1 
ATOM   5477  C  CA    . LEU C 1 253 ? 196.868 213.704 198.704 1.00 8.94   ? 253 LEU C CA    1 
ATOM   5478  C  C     . LEU C 1 253 ? 197.161 213.086 200.067 1.00 8.78   ? 253 LEU C C     1 
ATOM   5479  O  O     . LEU C 1 253 ? 196.481 212.129 200.475 1.00 8.64   ? 253 LEU C O     1 
ATOM   5480  C  CB    . LEU C 1 253 ? 195.394 213.577 198.314 1.00 8.84   ? 253 LEU C CB    1 
ATOM   5481  C  CG    . LEU C 1 253 ? 194.367 214.298 199.191 1.00 9.25   ? 253 LEU C CG    1 
ATOM   5482  C  CD1   . LEU C 1 253 ? 194.568 215.808 199.162 1.00 9.28   ? 253 LEU C CD1   1 
ATOM   5483  C  CD2   . LEU C 1 253 ? 192.974 213.929 198.714 1.00 9.55   ? 253 LEU C CD2   1 
ATOM   5484  N  N     . ASP C 1 254 ? 198.206 213.602 200.733 1.00 9.08   ? 254 ASP C N     1 
ATOM   5485  C  CA    . ASP C 1 254 ? 198.778 212.869 201.848 1.00 9.35   ? 254 ASP C CA    1 
ATOM   5486  C  C     . ASP C 1 254 ? 199.274 213.753 202.992 1.00 9.11   ? 254 ASP C C     1 
ATOM   5487  O  O     . ASP C 1 254 ? 199.866 213.228 203.933 1.00 10.02  ? 254 ASP C O     1 
ATOM   5488  C  CB    . ASP C 1 254 ? 199.906 211.988 201.348 1.00 9.75   ? 254 ASP C CB    1 
ATOM   5489  C  CG    . ASP C 1 254 ? 200.991 212.730 200.593 1.00 10.55  ? 254 ASP C CG    1 
ATOM   5490  O  OD1   . ASP C 1 254 ? 201.008 213.969 200.649 1.00 10.57  ? 254 ASP C OD1   1 
ATOM   5491  O  OD2   . ASP C 1 254 ? 201.802 212.068 199.936 1.00 11.90  ? 254 ASP C OD2   1 
ATOM   5492  N  N     . GLY C 1 255 ? 199.054 215.065 202.938 1.00 9.01   ? 255 GLY C N     1 
ATOM   5493  C  CA    . GLY C 1 255 ? 199.578 215.963 203.961 1.00 8.91   ? 255 GLY C CA    1 
ATOM   5494  C  C     . GLY C 1 255 ? 201.106 215.925 204.072 1.00 8.48   ? 255 GLY C C     1 
ATOM   5495  O  O     . GLY C 1 255 ? 201.645 216.093 205.153 1.00 8.16   ? 255 GLY C O     1 
ATOM   5496  N  N     . ALA C 1 256 ? 201.794 215.670 202.953 1.00 8.57   ? 256 ALA C N     1 
ATOM   5497  C  CA    . ALA C 1 256 ? 203.249 215.692 202.846 1.00 8.90   ? 256 ALA C CA    1 
ATOM   5498  C  C     . ALA C 1 256 ? 203.909 214.528 203.576 1.00 9.67   ? 256 ALA C C     1 
ATOM   5499  O  O     . ALA C 1 256 ? 205.100 214.600 203.863 1.00 9.47   ? 256 ALA C O     1 
ATOM   5500  C  CB    . ALA C 1 256 ? 203.823 217.005 203.359 1.00 8.80   ? 256 ALA C CB    1 
ATOM   5501  N  N     . ILE C 1 257 ? 203.174 213.443 203.836 1.00 10.51  ? 257 ILE C N     1 
ATOM   5502  C  CA    . ILE C 1 257 ? 203.756 212.294 204.504 1.00 11.79  ? 257 ILE C CA    1 
ATOM   5503  C  C     . ILE C 1 257 ? 204.616 211.509 203.521 1.00 11.98  ? 257 ILE C C     1 
ATOM   5504  O  O     . ILE C 1 257 ? 204.343 211.470 202.324 1.00 12.26  ? 257 ILE C O     1 
ATOM   5505  C  CB    . ILE C 1 257 ? 202.676 211.396 205.132 1.00 12.57  ? 257 ILE C CB    1 
ATOM   5506  C  CG1   . ILE C 1 257 ? 203.262 210.488 206.185 1.00 13.93  ? 257 ILE C CG1   1 
ATOM   5507  C  CG2   . ILE C 1 257 ? 201.921 210.607 204.065 1.00 12.66  ? 257 ILE C CG2   1 
ATOM   5508  C  CD1   . ILE C 1 257 ? 202.223 209.909 207.137 1.00 14.50  ? 257 ILE C CD1   1 
ATOM   5509  N  N     . ARG C 1 258 ? 205.676 210.902 204.058 1.00 13.08  ? 258 ARG C N     1 
ATOM   5510  C  CA    . ARG C 1 258 ? 206.457 209.902 203.365 1.00 14.25  ? 258 ARG C CA    1 
ATOM   5511  C  C     . ARG C 1 258 ? 206.570 208.713 204.311 1.00 16.63  ? 258 ARG C C     1 
ATOM   5512  O  O     . ARG C 1 258 ? 207.147 208.822 205.392 1.00 15.98  ? 258 ARG C O     1 
ATOM   5513  C  CB    . ARG C 1 258 ? 207.835 210.445 202.977 1.00 13.99  ? 258 ARG C CB    1 
ATOM   5514  C  CG    . ARG C 1 258 ? 207.790 211.620 202.016 1.00 13.29  ? 258 ARG C CG    1 
ATOM   5515  C  CD    . ARG C 1 258 ? 207.191 211.218 200.667 1.00 13.28  ? 258 ARG C CD    1 
ATOM   5516  N  NE    . ARG C 1 258 ? 207.244 212.322 199.708 1.00 12.94  ? 258 ARG C NE    1 
ATOM   5517  C  CZ    . ARG C 1 258 ? 206.327 213.283 199.574 1.00 13.49  ? 258 ARG C CZ    1 
ATOM   5518  N  NH1   . ARG C 1 258 ? 205.248 213.320 200.340 1.00 13.59  ? 258 ARG C NH1   1 
ATOM   5519  N  NH2   . ARG C 1 258 ? 206.493 214.219 198.657 1.00 14.01  ? 258 ARG C NH2   1 
ATOM   5520  N  N     . MET C 1 259 ? 205.997 207.580 203.907 1.00 18.61  ? 259 MET C N     1 
ATOM   5521  C  CA    . MET C 1 259 ? 205.831 206.454 204.811 1.00 21.75  ? 259 MET C CA    1 
ATOM   5522  C  C     . MET C 1 259 ? 207.185 205.821 205.124 1.00 21.53  ? 259 MET C C     1 
ATOM   5523  O  O     . MET C 1 259 ? 207.990 205.569 204.230 1.00 22.71  ? 259 MET C O     1 
ATOM   5524  C  CB    . MET C 1 259 ? 204.896 205.405 204.199 1.00 24.11  ? 259 MET C CB    1 
ATOM   5525  C  CG    . MET C 1 259 ? 203.550 205.959 203.792 1.00 27.02  ? 259 MET C CG    1 
ATOM   5526  S  SD    . MET C 1 259 ? 202.616 206.595 205.187 1.00 31.90  ? 259 MET C SD    1 
ATOM   5527  C  CE    . MET C 1 259 ? 202.287 205.099 206.119 1.00 34.29  ? 259 MET C CE    1 
ATOM   5528  N  N     . GLN C 1 260 ? 207.410 205.556 206.410 1.00 25.35  ? 260 GLN C N     1 
ATOM   5529  C  CA    . GLN C 1 260 ? 208.614 204.880 206.858 1.00 30.35  ? 260 GLN C CA    1 
ATOM   5530  C  C     . GLN C 1 260 ? 208.424 203.371 206.744 1.00 30.87  ? 260 GLN C C     1 
ATOM   5531  O  O     . GLN C 1 260 ? 207.297 202.880 206.677 1.00 32.10  ? 260 GLN C O     1 
ATOM   5532  C  CB    . GLN C 1 260 ? 208.954 205.282 208.287 1.00 33.65  ? 260 GLN C CB    1 
ATOM   5533  C  CG    . GLN C 1 260 ? 207.919 204.888 209.329 1.00 39.37  ? 260 GLN C CG    1 
ATOM   5534  C  CD    . GLN C 1 260 ? 208.305 205.349 210.724 1.00 44.39  ? 260 GLN C CD    1 
ATOM   5535  O  OE1   . GLN C 1 260 ? 209.365 205.952 210.945 1.00 50.74  ? 260 GLN C OE1   1 
ATOM   5536  N  NE2   . GLN C 1 260 ? 207.446 205.074 211.691 1.00 42.04  ? 260 GLN C NE2   1 
ATOM   5537  N  N     . PRO C 1 261 ? 209.519 202.585 206.694 1.00 32.62  ? 261 PRO C N     1 
ATOM   5538  C  CA    . PRO C 1 261 ? 209.378 201.128 206.623 1.00 36.86  ? 261 PRO C CA    1 
ATOM   5539  C  C     . PRO C 1 261 ? 208.663 200.563 207.854 1.00 43.02  ? 261 PRO C C     1 
ATOM   5540  O  O     . PRO C 1 261 ? 209.003 201.006 208.987 1.00 44.89  ? 261 PRO C O     1 
ATOM   5541  C  CB    . PRO C 1 261 ? 210.814 200.615 206.498 1.00 36.06  ? 261 PRO C CB    1 
ATOM   5542  C  CG    . PRO C 1 261 ? 211.662 201.745 207.027 1.00 35.09  ? 261 PRO C CG    1 
ATOM   5543  C  CD    . PRO C 1 261 ? 210.923 203.027 206.695 1.00 33.78  ? 261 PRO C CD    1 
ATOM   5544  O  OXT   . PRO C 1 261 ? 207.824 199.647 207.654 1.00 42.82  ? 261 PRO C OXT   1 
ATOM   5545  N  N     . SER D 1 7   ? 232.705 190.723 193.605 1.00 33.48  ? 7   SER D N     1 
ATOM   5546  C  CA    . SER D 1 7   ? 232.905 189.799 192.453 1.00 32.85  ? 7   SER D CA    1 
ATOM   5547  C  C     . SER D 1 7   ? 231.785 188.760 192.402 1.00 29.53  ? 7   SER D C     1 
ATOM   5548  O  O     . SER D 1 7   ? 231.304 188.314 193.438 1.00 30.79  ? 7   SER D O     1 
ATOM   5549  C  CB    . SER D 1 7   ? 234.257 189.130 192.497 1.00 35.41  ? 7   SER D CB    1 
ATOM   5550  O  OG    . SER D 1 7   ? 234.255 188.007 193.369 1.00 38.82  ? 7   SER D OG    1 
ATOM   5551  N  N     . VAL D 1 8   ? 231.422 188.346 191.189 1.00 26.68  ? 8   VAL D N     1 
ATOM   5552  C  CA    . VAL D 1 8   ? 230.361 187.374 190.996 1.00 24.56  ? 8   VAL D CA    1 
ATOM   5553  C  C     . VAL D 1 8   ? 230.920 185.958 190.884 1.00 24.27  ? 8   VAL D C     1 
ATOM   5554  O  O     . VAL D 1 8   ? 230.151 185.021 190.683 1.00 24.15  ? 8   VAL D O     1 
ATOM   5555  C  CB    . VAL D 1 8   ? 229.511 187.691 189.756 1.00 22.80  ? 8   VAL D CB    1 
ATOM   5556  C  CG1   . VAL D 1 8   ? 228.953 189.101 189.819 1.00 22.44  ? 8   VAL D CG1   1 
ATOM   5557  C  CG2   . VAL D 1 8   ? 230.280 187.458 188.469 1.00 22.16  ? 8   VAL D CG2   1 
ATOM   5558  N  N     . LYS D 1 9   ? 232.235 185.785 190.989 1.00 25.50  ? 9   LYS D N     1 
ATOM   5559  C  CA    . LYS D 1 9   ? 232.818 184.457 190.878 1.00 26.74  ? 9   LYS D CA    1 
ATOM   5560  C  C     . LYS D 1 9   ? 232.343 183.576 192.031 1.00 24.81  ? 9   LYS D C     1 
ATOM   5561  O  O     . LYS D 1 9   ? 232.421 183.968 193.196 1.00 25.72  ? 9   LYS D O     1 
ATOM   5562  C  CB    . LYS D 1 9   ? 234.347 184.529 190.864 1.00 31.82  ? 9   LYS D CB    1 
ATOM   5563  C  CG    . LYS D 1 9   ? 235.007 183.232 190.504 1.00 36.56  ? 9   LYS D CG    1 
ATOM   5564  C  CD    . LYS D 1 9   ? 236.522 183.361 190.406 1.00 42.18  ? 9   LYS D CD    1 
ATOM   5565  C  CE    . LYS D 1 9   ? 237.185 182.027 190.382 1.00 47.71  ? 9   LYS D CE    1 
ATOM   5566  N  NZ    . LYS D 1 9   ? 236.919 181.276 191.614 1.00 50.71  ? 9   LYS D NZ    1 
ATOM   5567  N  N     . GLY D 1 10  ? 231.846 182.382 191.694 1.00 22.59  ? 10  GLY D N     1 
ATOM   5568  C  CA    . GLY D 1 10  ? 231.362 181.442 192.687 1.00 22.44  ? 10  GLY D CA    1 
ATOM   5569  C  C     . GLY D 1 10  ? 229.897 181.650 193.071 1.00 21.74  ? 10  GLY D C     1 
ATOM   5570  O  O     . GLY D 1 10  ? 229.341 180.819 193.780 1.00 24.47  ? 10  GLY D O     1 
ATOM   5571  N  N     . LEU D 1 11  ? 229.272 182.753 192.638 1.00 19.65  ? 11  LEU D N     1 
ATOM   5572  C  CA    . LEU D 1 11  ? 227.872 182.988 192.950 1.00 17.99  ? 11  LEU D CA    1 
ATOM   5573  C  C     . LEU D 1 11  ? 226.984 182.104 192.080 1.00 16.26  ? 11  LEU D C     1 
ATOM   5574  O  O     . LEU D 1 11  ? 227.340 181.760 190.953 1.00 18.07  ? 11  LEU D O     1 
ATOM   5575  C  CB    . LEU D 1 11  ? 227.514 184.461 192.748 1.00 19.26  ? 11  LEU D CB    1 
ATOM   5576  C  CG    . LEU D 1 11  ? 228.190 185.456 193.698 1.00 19.79  ? 11  LEU D CG    1 
ATOM   5577  C  CD1   . LEU D 1 11  ? 227.612 186.844 193.474 1.00 21.26  ? 11  LEU D CD1   1 
ATOM   5578  C  CD2   . LEU D 1 11  ? 228.054 185.065 195.141 1.00 20.44  ? 11  LEU D CD2   1 
ATOM   5579  N  N     . VAL D 1 12  ? 225.810 181.762 192.616 1.00 14.98  ? 12  VAL D N     1 
ATOM   5580  C  CA    . VAL D 1 12  ? 224.818 180.997 191.885 1.00 13.81  ? 12  VAL D CA    1 
ATOM   5581  C  C     . VAL D 1 12  ? 223.637 181.913 191.590 1.00 13.26  ? 12  VAL D C     1 
ATOM   5582  O  O     . VAL D 1 12  ? 223.028 182.455 192.512 1.00 13.14  ? 12  VAL D O     1 
ATOM   5583  C  CB    . VAL D 1 12  ? 224.366 179.751 192.663 1.00 14.46  ? 12  VAL D CB    1 
ATOM   5584  C  CG1   . VAL D 1 12  ? 223.363 178.942 191.853 1.00 14.56  ? 12  VAL D CG1   1 
ATOM   5585  C  CG2   . VAL D 1 12  ? 225.558 178.896 193.077 1.00 14.35  ? 12  VAL D CG2   1 
ATOM   5586  N  N     . ALA D 1 13  ? 223.329 182.067 190.297 1.00 13.39  ? 13  ALA D N     1 
ATOM   5587  C  CA    . ALA D 1 13  ? 222.258 182.944 189.854 1.00 13.30  ? 13  ALA D CA    1 
ATOM   5588  C  C     . ALA D 1 13  ? 221.137 182.113 189.248 1.00 12.96  ? 13  ALA D C     1 
ATOM   5589  O  O     . ALA D 1 13  ? 221.375 181.273 188.386 1.00 13.56  ? 13  ALA D O     1 
ATOM   5590  C  CB    . ALA D 1 13  ? 222.771 183.954 188.860 1.00 13.29  ? 13  ALA D CB    1 
ATOM   5591  N  N     . VAL D 1 14  ? 219.910 182.367 189.716 1.00 13.29  ? 14  VAL D N     1 
ATOM   5592  C  CA    . VAL D 1 14  ? 218.722 181.846 189.062 1.00 12.63  ? 14  VAL D CA    1 
ATOM   5593  C  C     . VAL D 1 14  ? 218.180 182.936 188.156 1.00 12.14  ? 14  VAL D C     1 
ATOM   5594  O  O     . VAL D 1 14  ? 217.786 183.998 188.629 1.00 11.94  ? 14  VAL D O     1 
ATOM   5595  C  CB    . VAL D 1 14  ? 217.682 181.389 190.093 1.00 13.63  ? 14  VAL D CB    1 
ATOM   5596  C  CG1   . VAL D 1 14  ? 216.351 181.062 189.437 1.00 13.93  ? 14  VAL D CG1   1 
ATOM   5597  C  CG2   . VAL D 1 14  ? 218.213 180.210 190.902 1.00 13.89  ? 14  VAL D CG2   1 
ATOM   5598  N  N     . ILE D 1 15  ? 218.172 182.663 186.857 1.00 12.39  ? 15  ILE D N     1 
ATOM   5599  C  CA    . ILE D 1 15  ? 217.808 183.660 185.866 1.00 13.10  ? 15  ILE D CA    1 
ATOM   5600  C  C     . ILE D 1 15  ? 216.513 183.224 185.200 1.00 13.75  ? 15  ILE D C     1 
ATOM   5601  O  O     . ILE D 1 15  ? 216.468 182.245 184.470 1.00 13.40  ? 15  ILE D O     1 
ATOM   5602  C  CB    . ILE D 1 15  ? 218.929 183.876 184.845 1.00 13.42  ? 15  ILE D CB    1 
ATOM   5603  C  CG1   . ILE D 1 15  ? 220.207 184.301 185.549 1.00 14.19  ? 15  ILE D CG1   1 
ATOM   5604  C  CG2   . ILE D 1 15  ? 218.490 184.896 183.795 1.00 13.26  ? 15  ILE D CG2   1 
ATOM   5605  C  CD1   . ILE D 1 15  ? 221.446 184.181 184.709 1.00 15.02  ? 15  ILE D CD1   1 
ATOM   5606  N  N     . THR D 1 16  ? 215.453 183.974 185.485 1.00 14.00  ? 16  THR D N     1 
ATOM   5607  C  CA    . THR D 1 16  ? 214.152 183.675 184.929 1.00 15.55  ? 16  THR D CA    1 
ATOM   5608  C  C     . THR D 1 16  ? 214.092 184.170 183.488 1.00 15.93  ? 16  THR D C     1 
ATOM   5609  O  O     . THR D 1 16  ? 214.593 185.243 183.167 1.00 14.79  ? 16  THR D O     1 
ATOM   5610  C  CB    . THR D 1 16  ? 213.112 184.359 185.807 1.00 18.66  ? 16  THR D CB    1 
ATOM   5611  O  OG1   . THR D 1 16  ? 213.101 183.771 187.107 1.00 17.81  ? 16  THR D OG1   1 
ATOM   5612  C  CG2   . THR D 1 16  ? 211.755 184.103 185.253 1.00 23.54  ? 16  THR D CG2   1 
ATOM   5613  N  N     . GLY D 1 17  ? 213.452 183.398 182.618 1.00 16.11  ? 17  GLY D N     1 
ATOM   5614  C  CA    . GLY D 1 17  ? 213.444 183.711 181.199 1.00 16.12  ? 17  GLY D CA    1 
ATOM   5615  C  C     . GLY D 1 17  ? 214.856 183.673 180.607 1.00 16.45  ? 17  GLY D C     1 
ATOM   5616  O  O     . GLY D 1 17  ? 215.175 184.449 179.717 1.00 16.76  ? 17  GLY D O     1 
ATOM   5617  N  N     . GLY D 1 18  ? 215.696 182.754 181.091 1.00 16.91  ? 18  GLY D N     1 
ATOM   5618  C  CA    . GLY D 1 18  ? 217.116 182.748 180.767 1.00 18.11  ? 18  GLY D CA    1 
ATOM   5619  C  C     . GLY D 1 18  ? 217.452 182.059 179.446 1.00 19.17  ? 18  GLY D C     1 
ATOM   5620  O  O     . GLY D 1 18  ? 218.622 182.001 179.090 1.00 19.76  ? 18  GLY D O     1 
ATOM   5621  N  N     . ALA D 1 19  ? 216.455 181.549 178.717 1.00 20.41  ? 19  ALA D N     1 
ATOM   5622  C  CA    . ALA D 1 19  ? 216.717 180.858 177.459 1.00 22.34  ? 19  ALA D CA    1 
ATOM   5623  C  C     . ALA D 1 19  ? 216.888 181.824 176.288 1.00 23.15  ? 19  ALA D C     1 
ATOM   5624  O  O     . ALA D 1 19  ? 217.343 181.399 175.228 1.00 24.00  ? 19  ALA D O     1 
ATOM   5625  C  CB    . ALA D 1 19  ? 215.601 179.883 177.141 1.00 23.94  ? 19  ALA D CB    1 
ATOM   5626  N  N     . SER D 1 20  ? 216.531 183.103 176.456 1.00 22.17  ? 20  SER D N     1 
ATOM   5627  C  CA    . SER D 1 20  ? 216.635 184.055 175.366 1.00 22.15  ? 20  SER D CA    1 
ATOM   5628  C  C     . SER D 1 20  ? 216.668 185.478 175.910 1.00 20.90  ? 20  SER D C     1 
ATOM   5629  O  O     . SER D 1 20  ? 216.418 185.704 177.088 1.00 21.91  ? 20  SER D O     1 
ATOM   5630  C  CB    . SER D 1 20  ? 215.502 183.885 174.388 1.00 24.40  ? 20  SER D CB    1 
ATOM   5631  O  OG    . SER D 1 20  ? 214.267 184.305 174.948 1.00 25.18  ? 20  SER D OG    1 
ATOM   5632  N  N     . GLY D 1 21  ? 216.977 186.426 175.026 1.00 19.17  ? 21  GLY D N     1 
ATOM   5633  C  CA    . GLY D 1 21  ? 216.827 187.841 175.323 1.00 18.28  ? 21  GLY D CA    1 
ATOM   5634  C  C     . GLY D 1 21  ? 217.728 188.286 176.471 1.00 16.41  ? 21  GLY D C     1 
ATOM   5635  O  O     . GLY D 1 21  ? 218.890 187.890 176.551 1.00 16.57  ? 21  GLY D O     1 
ATOM   5636  N  N     . LEU D 1 22  ? 217.179 189.132 177.351 1.00 14.94  ? 22  LEU D N     1 
ATOM   5637  C  CA    . LEU D 1 22  ? 217.940 189.718 178.440 1.00 14.21  ? 22  LEU D CA    1 
ATOM   5638  C  C     . LEU D 1 22  ? 218.430 188.639 179.398 1.00 13.42  ? 22  LEU D C     1 
ATOM   5639  O  O     . LEU D 1 22  ? 219.554 188.708 179.881 1.00 13.75  ? 22  LEU D O     1 
ATOM   5640  C  CB    . LEU D 1 22  ? 217.092 190.755 179.173 1.00 14.86  ? 22  LEU D CB    1 
ATOM   5641  C  CG    . LEU D 1 22  ? 216.598 191.928 178.325 1.00 16.57  ? 22  LEU D CG    1 
ATOM   5642  C  CD1   . LEU D 1 22  ? 215.805 192.889 179.203 1.00 17.28  ? 22  LEU D CD1   1 
ATOM   5643  C  CD2   . LEU D 1 22  ? 217.730 192.617 177.584 1.00 16.69  ? 22  LEU D CD2   1 
ATOM   5644  N  N     . GLY D 1 23  ? 217.579 187.656 179.693 1.00 12.77  ? 23  GLY D N     1 
ATOM   5645  C  CA    . GLY D 1 23  ? 217.947 186.588 180.601 1.00 12.51  ? 23  GLY D CA    1 
ATOM   5646  C  C     . GLY D 1 23  ? 219.140 185.786 180.098 1.00 12.79  ? 23  GLY D C     1 
ATOM   5647  O  O     . GLY D 1 23  ? 220.044 185.470 180.863 1.00 12.77  ? 23  GLY D O     1 
ATOM   5648  N  N     . LEU D 1 24  ? 219.148 185.452 178.810 1.00 13.86  ? 24  LEU D N     1 
ATOM   5649  C  CA    . LEU D 1 24  ? 220.242 184.676 178.244 1.00 14.03  ? 24  LEU D CA    1 
ATOM   5650  C  C     . LEU D 1 24  ? 221.542 185.474 178.281 1.00 13.42  ? 24  LEU D C     1 
ATOM   5651  O  O     . LEU D 1 24  ? 222.575 184.941 178.661 1.00 14.73  ? 24  LEU D O     1 
ATOM   5652  C  CB    . LEU D 1 24  ? 219.914 184.241 176.821 1.00 14.97  ? 24  LEU D CB    1 
ATOM   5653  C  CG    . LEU D 1 24  ? 221.010 183.447 176.104 1.00 15.59  ? 24  LEU D CG    1 
ATOM   5654  C  CD1   . LEU D 1 24  ? 221.399 182.218 176.888 1.00 16.05  ? 24  LEU D CD1   1 
ATOM   5655  C  CD2   . LEU D 1 24  ? 220.569 183.089 174.700 1.00 16.46  ? 24  LEU D CD2   1 
ATOM   5656  N  N     . ALA D 1 25  ? 221.491 186.751 177.900 1.00 13.00  ? 25  ALA D N     1 
ATOM   5657  C  CA    . ALA D 1 25  ? 222.685 187.588 177.918 1.00 12.51  ? 25  ALA D CA    1 
ATOM   5658  C  C     . ALA D 1 25  ? 223.233 187.693 179.343 1.00 11.87  ? 25  ALA D C     1 
ATOM   5659  O  O     . ALA D 1 25  ? 224.442 187.707 179.544 1.00 11.41  ? 25  ALA D O     1 
ATOM   5660  C  CB    . ALA D 1 25  ? 222.380 188.957 177.346 1.00 12.38  ? 25  ALA D CB    1 
ATOM   5661  N  N     . THR D 1 26  ? 222.343 187.789 180.333 1.00 11.39  ? 26  THR D N     1 
ATOM   5662  C  CA    . THR D 1 26  ? 222.764 187.826 181.722 1.00 11.84  ? 26  THR D CA    1 
ATOM   5663  C  C     . THR D 1 26  ? 223.471 186.526 182.093 1.00 12.18  ? 26  THR D C     1 
ATOM   5664  O  O     . THR D 1 26  ? 224.473 186.539 182.796 1.00 12.44  ? 26  THR D O     1 
ATOM   5665  C  CB    . THR D 1 26  ? 221.569 188.079 182.643 1.00 11.15  ? 26  THR D CB    1 
ATOM   5666  O  OG1   . THR D 1 26  ? 220.937 189.289 182.244 1.00 11.00  ? 26  THR D OG1   1 
ATOM   5667  C  CG2   . THR D 1 26  ? 222.004 188.178 184.089 1.00 11.06  ? 26  THR D CG2   1 
ATOM   5668  N  N     . ALA D 1 27  ? 222.935 185.389 181.638 1.00 14.43  ? 27  ALA D N     1 
ATOM   5669  C  CA    . ALA D 1 27  ? 223.546 184.095 181.914 1.00 14.30  ? 27  ALA D CA    1 
ATOM   5670  C  C     . ALA D 1 27  ? 224.930 183.993 181.285 1.00 14.85  ? 27  ALA D C     1 
ATOM   5671  O  O     . ALA D 1 27  ? 225.863 183.530 181.937 1.00 15.12  ? 27  ALA D O     1 
ATOM   5672  C  CB    . ALA D 1 27  ? 222.654 182.977 181.437 1.00 14.74  ? 27  ALA D CB    1 
ATOM   5673  N  N     . GLU D 1 28  ? 225.070 184.432 180.036 1.00 17.22  ? 28  GLU D N     1 
ATOM   5674  C  CA    . GLU D 1 28  ? 226.343 184.331 179.340 1.00 19.31  ? 28  GLU D CA    1 
ATOM   5675  C  C     . GLU D 1 28  ? 227.408 185.157 180.057 1.00 18.04  ? 28  GLU D C     1 
ATOM   5676  O  O     . GLU D 1 28  ? 228.545 184.710 180.199 1.00 19.45  ? 28  GLU D O     1 
ATOM   5677  C  CB    . GLU D 1 28  ? 226.229 184.782 177.884 1.00 22.91  ? 28  GLU D CB    1 
ATOM   5678  C  CG    . GLU D 1 28  ? 225.110 184.100 177.111 1.00 27.98  ? 28  GLU D CG    1 
ATOM   5679  C  CD    . GLU D 1 28  ? 224.845 184.742 175.755 1.00 34.57  ? 28  GLU D CD    1 
ATOM   5680  O  OE1   . GLU D 1 28  ? 224.637 185.985 175.690 1.00 37.26  ? 28  GLU D OE1   1 
ATOM   5681  O  OE2   . GLU D 1 28  ? 224.814 183.981 174.758 1.00 37.58  ? 28  GLU D OE2   1 
ATOM   5682  N  N     . ARG D 1 29  ? 227.051 186.367 180.503 1.00 16.67  ? 29  ARG D N     1 
ATOM   5683  C  CA    . ARG D 1 29  ? 228.016 187.226 181.168 1.00 16.39  ? 29  ARG D CA    1 
ATOM   5684  C  C     . ARG D 1 29  ? 228.433 186.630 182.508 1.00 15.60  ? 29  ARG D C     1 
ATOM   5685  O  O     . ARG D 1 29  ? 229.623 186.533 182.805 1.00 16.31  ? 29  ARG D O     1 
ATOM   5686  C  CB    . ARG D 1 29  ? 227.466 188.644 181.355 1.00 16.85  ? 29  ARG D CB    1 
ATOM   5687  C  CG    . ARG D 1 29  ? 228.498 189.550 182.005 1.00 17.93  ? 29  ARG D CG    1 
ATOM   5688  C  CD    . ARG D 1 29  ? 228.033 190.985 182.050 1.00 19.72  ? 29  ARG D CD    1 
ATOM   5689  N  NE    . ARG D 1 29  ? 229.083 191.838 182.608 1.00 20.90  ? 29  ARG D NE    1 
ATOM   5690  C  CZ    . ARG D 1 29  ? 230.066 192.402 181.932 1.00 22.16  ? 29  ARG D CZ    1 
ATOM   5691  N  NH1   . ARG D 1 29  ? 230.114 192.338 180.615 1.00 23.29  ? 29  ARG D NH1   1 
ATOM   5692  N  NH2   . ARG D 1 29  ? 230.984 193.092 182.583 1.00 24.46  ? 29  ARG D NH2   1 
ATOM   5693  N  N     . LEU D 1 30  ? 227.455 186.254 183.333 1.00 16.12  ? 30  LEU D N     1 
ATOM   5694  C  CA    . LEU D 1 30  ? 227.748 185.773 184.676 1.00 16.42  ? 30  LEU D CA    1 
ATOM   5695  C  C     . LEU D 1 30  ? 228.555 184.479 184.614 1.00 16.99  ? 30  LEU D C     1 
ATOM   5696  O  O     . LEU D 1 30  ? 229.490 184.296 185.386 1.00 17.64  ? 30  LEU D O     1 
ATOM   5697  C  CB    . LEU D 1 30  ? 226.465 185.598 185.482 1.00 16.59  ? 30  LEU D CB    1 
ATOM   5698  C  CG    . LEU D 1 30  ? 225.678 186.880 185.773 1.00 16.76  ? 30  LEU D CG    1 
ATOM   5699  C  CD1   . LEU D 1 30  ? 224.398 186.562 186.524 1.00 16.66  ? 30  LEU D CD1   1 
ATOM   5700  C  CD2   . LEU D 1 30  ? 226.555 187.870 186.521 1.00 17.16  ? 30  LEU D CD2   1 
ATOM   5701  N  N     . VAL D 1 31  ? 228.185 183.564 183.719 1.00 17.85  ? 31  VAL D N     1 
ATOM   5702  C  CA    . VAL D 1 31  ? 228.934 182.326 183.570 1.00 19.44  ? 31  VAL D CA    1 
ATOM   5703  C  C     . VAL D 1 31  ? 230.355 182.626 183.092 1.00 20.69  ? 31  VAL D C     1 
ATOM   5704  O  O     . VAL D 1 31  ? 231.316 182.039 183.582 1.00 22.67  ? 31  VAL D O     1 
ATOM   5705  C  CB    . VAL D 1 31  ? 228.208 181.348 182.632 1.00 20.03  ? 31  VAL D CB    1 
ATOM   5706  C  CG1   . VAL D 1 31  ? 229.125 180.223 182.174 1.00 21.66  ? 31  VAL D CG1   1 
ATOM   5707  C  CG2   . VAL D 1 31  ? 226.967 180.783 183.304 1.00 20.26  ? 31  VAL D CG2   1 
ATOM   5708  N  N     . GLY D 1 32  ? 230.492 183.545 182.138 1.00 21.47  ? 32  GLY D N     1 
ATOM   5709  C  CA    . GLY D 1 32  ? 231.800 183.969 181.661 1.00 21.93  ? 32  GLY D CA    1 
ATOM   5710  C  C     . GLY D 1 32  ? 232.655 184.610 182.756 1.00 22.26  ? 32  GLY D C     1 
ATOM   5711  O  O     . GLY D 1 32  ? 233.878 184.582 182.675 1.00 25.24  ? 32  GLY D O     1 
ATOM   5712  N  N     . GLN D 1 33  ? 232.013 185.202 183.769 1.00 22.78  ? 33  GLN D N     1 
ATOM   5713  C  CA    . GLN D 1 33  ? 232.717 185.844 184.869 1.00 23.03  ? 33  GLN D CA    1 
ATOM   5714  C  C     . GLN D 1 33  ? 232.931 184.892 186.045 1.00 22.15  ? 33  GLN D C     1 
ATOM   5715  O  O     . GLN D 1 33  ? 233.419 185.321 187.087 1.00 23.41  ? 33  GLN D O     1 
ATOM   5716  C  CB    . GLN D 1 33  ? 231.935 187.066 185.349 1.00 25.55  ? 33  GLN D CB    1 
ATOM   5717  C  CG    . GLN D 1 33  ? 231.842 188.185 184.320 1.00 27.55  ? 33  GLN D CG    1 
ATOM   5718  C  CD    . GLN D 1 33  ? 233.063 189.068 184.332 1.00 30.61  ? 33  GLN D CD    1 
ATOM   5719  O  OE1   . GLN D 1 33  ? 233.375 189.680 185.360 1.00 34.36  ? 33  GLN D OE1   1 
ATOM   5720  N  NE2   . GLN D 1 33  ? 233.764 189.130 183.210 1.00 34.45  ? 33  GLN D NE2   1 
ATOM   5721  N  N     . GLY D 1 34  ? 232.575 183.610 185.894 1.00 20.57  ? 34  GLY D N     1 
ATOM   5722  C  CA    . GLY D 1 34  ? 232.891 182.608 186.898 1.00 20.55  ? 34  GLY D CA    1 
ATOM   5723  C  C     . GLY D 1 34  ? 231.707 182.219 187.782 1.00 19.76  ? 34  GLY D C     1 
ATOM   5724  O  O     . GLY D 1 34  ? 231.881 181.432 188.709 1.00 21.00  ? 34  GLY D O     1 
ATOM   5725  N  N     . ALA D 1 35  ? 230.507 182.739 187.499 1.00 20.19  ? 35  ALA D N     1 
ATOM   5726  C  CA    . ALA D 1 35  ? 229.331 182.387 188.279 1.00 18.64  ? 35  ALA D CA    1 
ATOM   5727  C  C     . ALA D 1 35  ? 228.664 181.141 187.701 1.00 18.17  ? 35  ALA D C     1 
ATOM   5728  O  O     . ALA D 1 35  ? 228.960 180.711 186.590 1.00 19.09  ? 35  ALA D O     1 
ATOM   5729  C  CB    . ALA D 1 35  ? 228.364 183.548 188.331 1.00 19.24  ? 35  ALA D CB    1 
ATOM   5730  N  N     . SER D 1 36  ? 227.756 180.560 188.491 1.00 18.39  ? 36  SER D N     1 
ATOM   5731  C  CA    . SER D 1 36  ? 226.897 179.475 188.044 1.00 18.13  ? 36  SER D CA    1 
ATOM   5732  C  C     . SER D 1 36  ? 225.489 180.022 187.807 1.00 18.09  ? 36  SER D C     1 
ATOM   5733  O  O     . SER D 1 36  ? 224.988 180.824 188.594 1.00 18.23  ? 36  SER D O     1 
ATOM   5734  C  CB    . SER D 1 36  ? 226.878 178.348 189.039 1.00 18.89  ? 36  SER D CB    1 
ATOM   5735  O  OG    . SER D 1 36  ? 228.195 177.919 189.365 1.00 19.70  ? 36  SER D OG    1 
ATOM   5736  N  N     . ALA D 1 37  ? 224.866 179.590 186.705 1.00 17.78  ? 37  ALA D N     1 
ATOM   5737  C  CA    . ALA D 1 37  ? 223.560 180.082 186.306 1.00 17.64  ? 37  ALA D CA    1 
ATOM   5738  C  C     . ALA D 1 37  ? 222.584 178.919 186.177 1.00 19.10  ? 37  ALA D C     1 
ATOM   5739  O  O     . ALA D 1 37  ? 222.933 177.837 185.712 1.00 19.85  ? 37  ALA D O     1 
ATOM   5740  C  CB    . ALA D 1 37  ? 223.659 180.838 185.006 1.00 17.70  ? 37  ALA D CB    1 
ATOM   5741  N  N     . VAL D 1 38  ? 221.339 179.172 186.586 1.00 18.51  ? 38  VAL D N     1 
ATOM   5742  C  CA    . VAL D 1 38  ? 220.230 178.268 186.353 1.00 17.87  ? 38  VAL D CA    1 
ATOM   5743  C  C     . VAL D 1 38  ? 219.239 178.974 185.439 1.00 18.09  ? 38  VAL D C     1 
ATOM   5744  O  O     . VAL D 1 38  ? 218.675 180.006 185.807 1.00 18.71  ? 38  VAL D O     1 
ATOM   5745  C  CB    . VAL D 1 38  ? 219.579 177.863 187.680 1.00 18.52  ? 38  VAL D CB    1 
ATOM   5746  C  CG1   . VAL D 1 38  ? 218.325 177.025 187.463 1.00 18.85  ? 38  VAL D CG1   1 
ATOM   5747  C  CG2   . VAL D 1 38  ? 220.587 177.166 188.580 1.00 19.40  ? 38  VAL D CG2   1 
ATOM   5748  N  N     . LEU D 1 39  ? 219.040 178.416 184.244 1.00 17.48  ? 39  LEU D N     1 
ATOM   5749  C  CA    . LEU D 1 39  ? 218.114 178.990 183.285 1.00 17.18  ? 39  LEU D CA    1 
ATOM   5750  C  C     . LEU D 1 39  ? 216.707 178.501 183.598 1.00 18.08  ? 39  LEU D C     1 
ATOM   5751  O  O     . LEU D 1 39  ? 216.370 177.347 183.344 1.00 18.85  ? 39  LEU D O     1 
ATOM   5752  C  CB    . LEU D 1 39  ? 218.509 178.626 181.857 1.00 18.32  ? 39  LEU D CB    1 
ATOM   5753  C  CG    . LEU D 1 39  ? 219.945 178.952 181.449 1.00 18.69  ? 39  LEU D CG    1 
ATOM   5754  C  CD1   . LEU D 1 39  ? 220.115 178.719 179.952 1.00 18.99  ? 39  LEU D CD1   1 
ATOM   5755  C  CD2   . LEU D 1 39  ? 220.314 180.373 181.818 1.00 19.08  ? 39  LEU D CD2   1 
ATOM   5756  N  N     . LEU D 1 40  ? 215.888 179.400 184.152 1.00 18.44  ? 40  LEU D N     1 
ATOM   5757  C  CA    . LEU D 1 40  ? 214.498 179.113 184.451 1.00 18.84  ? 40  LEU D CA    1 
ATOM   5758  C  C     . LEU D 1 40  ? 213.662 179.677 183.308 1.00 19.44  ? 40  LEU D C     1 
ATOM   5759  O  O     . LEU D 1 40  ? 213.530 180.891 183.154 1.00 19.89  ? 40  LEU D O     1 
ATOM   5760  C  CB    . LEU D 1 40  ? 214.142 179.707 185.818 1.00 19.24  ? 40  LEU D CB    1 
ATOM   5761  C  CG    . LEU D 1 40  ? 212.856 179.210 186.487 1.00 19.68  ? 40  LEU D CG    1 
ATOM   5762  C  CD1   . LEU D 1 40  ? 212.907 179.438 187.974 1.00 19.41  ? 40  LEU D CD1   1 
ATOM   5763  C  CD2   . LEU D 1 40  ? 211.610 179.880 185.922 1.00 20.01  ? 40  LEU D CD2   1 
ATOM   5764  N  N     . ASP D 1 41  ? 213.107 178.776 182.496 1.00 19.48  ? 41  ASP D N     1 
ATOM   5765  C  CA    . ASP D 1 41  ? 212.290 179.176 181.366 1.00 20.85  ? 41  ASP D CA    1 
ATOM   5766  C  C     . ASP D 1 41  ? 211.313 178.054 181.040 1.00 19.56  ? 41  ASP D C     1 
ATOM   5767  O  O     . ASP D 1 41  ? 211.379 176.976 181.624 1.00 19.09  ? 41  ASP D O     1 
ATOM   5768  C  CB    . ASP D 1 41  ? 213.139 179.561 180.164 1.00 22.87  ? 41  ASP D CB    1 
ATOM   5769  C  CG    . ASP D 1 41  ? 212.523 180.649 179.298 1.00 26.04  ? 41  ASP D CG    1 
ATOM   5770  O  OD1   . ASP D 1 41  ? 211.275 180.704 179.219 1.00 27.61  ? 41  ASP D OD1   1 
ATOM   5771  O  OD2   . ASP D 1 41  ? 213.292 181.459 178.734 1.00 27.23  ? 41  ASP D OD2   1 
ATOM   5772  N  N     . LEU D 1 42  ? 210.406 178.325 180.104 1.00 20.19  ? 42  LEU D N     1 
ATOM   5773  C  CA    . LEU D 1 42  ? 209.377 177.365 179.749 1.00 22.01  ? 42  LEU D CA    1 
ATOM   5774  C  C     . LEU D 1 42  ? 210.004 176.124 179.126 1.00 21.65  ? 42  LEU D C     1 
ATOM   5775  O  O     . LEU D 1 42  ? 211.078 176.188 178.541 1.00 20.90  ? 42  LEU D O     1 
ATOM   5776  C  CB    . LEU D 1 42  ? 208.365 178.012 178.809 1.00 22.64  ? 42  LEU D CB    1 
ATOM   5777  C  CG    . LEU D 1 42  ? 207.521 179.128 179.430 1.00 23.31  ? 42  LEU D CG    1 
ATOM   5778  C  CD1   . LEU D 1 42  ? 206.749 179.885 178.378 1.00 24.78  ? 42  LEU D CD1   1 
ATOM   5779  C  CD2   . LEU D 1 42  ? 206.585 178.581 180.479 1.00 23.82  ? 42  LEU D CD2   1 
ATOM   5780  N  N     . PRO D 1 43  ? 209.344 174.954 179.241 1.00 25.54  ? 43  PRO D N     1 
ATOM   5781  C  CA    . PRO D 1 43  ? 209.842 173.726 178.624 1.00 27.72  ? 43  PRO D CA    1 
ATOM   5782  C  C     . PRO D 1 43  ? 210.131 173.817 177.131 1.00 29.93  ? 43  PRO D C     1 
ATOM   5783  O  O     . PRO D 1 43  ? 211.031 173.138 176.647 1.00 33.74  ? 43  PRO D O     1 
ATOM   5784  C  CB    . PRO D 1 43  ? 208.731 172.718 178.920 1.00 27.21  ? 43  PRO D CB    1 
ATOM   5785  C  CG    . PRO D 1 43  ? 208.111 173.223 180.177 1.00 26.96  ? 43  PRO D CG    1 
ATOM   5786  C  CD    . PRO D 1 43  ? 208.107 174.730 180.000 1.00 26.83  ? 43  PRO D CD    1 
ATOM   5787  N  N     . ASN D 1 44  ? 209.383 174.650 176.406 1.00 33.29  ? 44  ASN D N     1 
ATOM   5788  C  CA    . ASN D 1 44  ? 209.538 174.753 174.960 1.00 39.18  ? 44  ASN D CA    1 
ATOM   5789  C  C     . ASN D 1 44  ? 210.452 175.912 174.548 1.00 38.16  ? 44  ASN D C     1 
ATOM   5790  O  O     . ASN D 1 44  ? 210.532 176.238 173.365 1.00 40.74  ? 44  ASN D O     1 
ATOM   5791  C  CB    . ASN D 1 44  ? 208.180 174.909 174.282 1.00 45.38  ? 44  ASN D CB    1 
ATOM   5792  C  CG    . ASN D 1 44  ? 207.431 176.147 174.722 1.00 53.16  ? 44  ASN D CG    1 
ATOM   5793  O  OD1   . ASN D 1 44  ? 207.918 176.953 175.526 1.00 55.10  ? 44  ASN D OD1   1 
ATOM   5794  N  ND2   . ASN D 1 44  ? 206.199 176.275 174.263 1.00 57.61  ? 44  ASN D ND2   1 
ATOM   5795  N  N     . SER D 1 45  ? 211.150 176.532 175.504 1.00 36.18  ? 45  SER D N     1 
ATOM   5796  C  CA    . SER D 1 45  ? 211.930 177.734 175.222 1.00 35.39  ? 45  SER D CA    1 
ATOM   5797  C  C     . SER D 1 45  ? 213.278 177.425 174.575 1.00 36.31  ? 45  SER D C     1 
ATOM   5798  O  O     . SER D 1 45  ? 213.979 178.340 174.139 1.00 36.42  ? 45  SER D O     1 
ATOM   5799  C  CB    . SER D 1 45  ? 212.138 178.559 176.463 1.00 34.30  ? 45  SER D CB    1 
ATOM   5800  O  OG    . SER D 1 45  ? 212.767 177.787 177.468 1.00 32.79  ? 45  SER D OG    1 
ATOM   5801  N  N     . GLY D 1 46  ? 213.684 176.155 174.542 1.00 36.45  ? 46  GLY D N     1 
ATOM   5802  C  CA    . GLY D 1 46  ? 214.994 175.808 174.017 1.00 34.39  ? 46  GLY D CA    1 
ATOM   5803  C  C     . GLY D 1 46  ? 216.120 176.099 175.008 1.00 33.66  ? 46  GLY D C     1 
ATOM   5804  O  O     . GLY D 1 46  ? 217.260 176.238 174.603 1.00 32.37  ? 46  GLY D O     1 
ATOM   5805  N  N     . GLY D 1 47  ? 215.802 176.163 176.302 1.00 31.98  ? 47  GLY D N     1 
ATOM   5806  C  CA    . GLY D 1 47  ? 216.791 176.463 177.320 1.00 30.63  ? 47  GLY D CA    1 
ATOM   5807  C  C     . GLY D 1 47  ? 217.812 175.348 177.509 1.00 28.04  ? 47  GLY D C     1 
ATOM   5808  O  O     . GLY D 1 47  ? 218.928 175.611 177.948 1.00 27.10  ? 47  GLY D O     1 
ATOM   5809  N  N     . GLU D 1 48  ? 217.441 174.104 177.192 1.00 30.07  ? 48  GLU D N     1 
ATOM   5810  C  CA    . GLU D 1 48  ? 218.368 172.991 177.326 1.00 32.31  ? 48  GLU D CA    1 
ATOM   5811  C  C     . GLU D 1 48  ? 219.585 173.176 176.418 1.00 28.04  ? 48  GLU D C     1 
ATOM   5812  O  O     . GLU D 1 48  ? 220.714 172.930 176.831 1.00 27.22  ? 48  GLU D O     1 
ATOM   5813  C  CB    . GLU D 1 48  ? 217.660 171.669 177.038 1.00 39.21  ? 48  GLU D CB    1 
ATOM   5814  C  CG    . GLU D 1 48  ? 218.538 170.446 177.278 1.00 46.14  ? 48  GLU D CG    1 
ATOM   5815  C  CD    . GLU D 1 48  ? 219.023 170.338 178.713 1.00 55.35  ? 48  GLU D CD    1 
ATOM   5816  O  OE1   . GLU D 1 48  ? 218.143 170.380 179.597 1.00 61.02  ? 48  GLU D OE1   1 
ATOM   5817  O  OE2   . GLU D 1 48  ? 220.257 170.310 178.935 1.00 60.87  ? 48  GLU D OE2   1 
ATOM   5818  N  N     . ALA D 1 49  ? 219.359 173.620 175.180 1.00 27.26  ? 49  ALA D N     1 
ATOM   5819  C  CA    . ALA D 1 49  ? 220.455 173.864 174.251 1.00 27.30  ? 49  ALA D CA    1 
ATOM   5820  C  C     . ALA D 1 49  ? 221.331 175.018 174.740 1.00 26.75  ? 49  ALA D C     1 
ATOM   5821  O  O     . ALA D 1 49  ? 222.553 174.950 174.655 1.00 26.50  ? 49  ALA D O     1 
ATOM   5822  C  CB    . ALA D 1 49  ? 219.915 174.145 172.866 1.00 26.91  ? 49  ALA D CB    1 
ATOM   5823  N  N     . GLN D 1 50  ? 220.713 176.082 175.266 1.00 26.38  ? 50  GLN D N     1 
ATOM   5824  C  CA    . GLN D 1 50  ? 221.472 177.210 175.775 1.00 25.64  ? 50  GLN D CA    1 
ATOM   5825  C  C     . GLN D 1 50  ? 222.313 176.802 176.981 1.00 23.64  ? 50  GLN D C     1 
ATOM   5826  O  O     . GLN D 1 50  ? 223.472 177.202 177.091 1.00 25.48  ? 50  GLN D O     1 
ATOM   5827  C  CB    . GLN D 1 50  ? 220.541 178.364 176.130 1.00 26.64  ? 50  GLN D CB    1 
ATOM   5828  C  CG    . GLN D 1 50  ? 219.820 178.972 174.937 1.00 29.18  ? 50  GLN D CG    1 
ATOM   5829  C  CD    . GLN D 1 50  ? 220.752 179.393 173.827 1.00 30.69  ? 50  GLN D CD    1 
ATOM   5830  O  OE1   . GLN D 1 50  ? 221.863 179.885 174.050 1.00 31.55  ? 50  GLN D OE1   1 
ATOM   5831  N  NE2   . GLN D 1 50  ? 220.304 179.208 172.597 1.00 35.06  ? 50  GLN D NE2   1 
ATOM   5832  N  N     . ALA D 1 51  ? 221.733 176.020 177.895 1.00 23.76  ? 51  ALA D N     1 
ATOM   5833  C  CA    . ALA D 1 51  ? 222.458 175.589 179.079 1.00 24.84  ? 51  ALA D CA    1 
ATOM   5834  C  C     . ALA D 1 51  ? 223.652 174.714 178.697 1.00 26.92  ? 51  ALA D C     1 
ATOM   5835  O  O     . ALA D 1 51  ? 224.725 174.835 179.284 1.00 28.18  ? 51  ALA D O     1 
ATOM   5836  C  CB    . ALA D 1 51  ? 221.536 174.874 180.037 1.00 24.59  ? 51  ALA D CB    1 
ATOM   5837  N  N     . LYS D 1 52  ? 223.464 173.822 177.722 1.00 28.48  ? 52  LYS D N     1 
ATOM   5838  C  CA    . LYS D 1 52  ? 224.555 172.995 177.229 1.00 30.91  ? 52  LYS D CA    1 
ATOM   5839  C  C     . LYS D 1 52  ? 225.640 173.863 176.592 1.00 29.42  ? 52  LYS D C     1 
ATOM   5840  O  O     . LYS D 1 52  ? 226.824 173.593 176.749 1.00 29.37  ? 52  LYS D O     1 
ATOM   5841  C  CB    . LYS D 1 52  ? 224.025 171.961 176.233 1.00 34.48  ? 52  LYS D CB    1 
ATOM   5842  C  CG    . LYS D 1 52  ? 225.083 171.066 175.622 1.00 41.62  ? 52  LYS D CG    1 
ATOM   5843  C  CD    . LYS D 1 52  ? 224.487 169.902 174.850 1.00 48.71  ? 52  LYS D CD    1 
ATOM   5844  C  CE    . LYS D 1 52  ? 225.535 169.160 174.079 1.00 53.11  ? 52  LYS D CE    1 
ATOM   5845  N  NZ    . LYS D 1 52  ? 224.907 168.431 172.977 1.00 55.57  ? 52  LYS D NZ    1 
ATOM   5846  N  N     . LYS D 1 53  ? 225.234 174.901 175.859 1.00 29.20  ? 53  LYS D N     1 
ATOM   5847  C  CA    . LYS D 1 53  ? 226.187 175.779 175.202 1.00 31.00  ? 53  LYS D CA    1 
ATOM   5848  C  C     . LYS D 1 53  ? 227.029 176.540 176.227 1.00 31.57  ? 53  LYS D C     1 
ATOM   5849  O  O     . LYS D 1 53  ? 228.198 176.808 175.977 1.00 32.52  ? 53  LYS D O     1 
ATOM   5850  C  CB    . LYS D 1 53  ? 225.434 176.734 174.273 1.00 35.32  ? 53  LYS D CB    1 
ATOM   5851  C  CG    . LYS D 1 53  ? 226.263 177.789 173.587 1.00 40.38  ? 53  LYS D CG    1 
ATOM   5852  C  CD    . LYS D 1 53  ? 225.483 178.465 172.464 1.00 45.02  ? 53  LYS D CD    1 
ATOM   5853  C  CE    . LYS D 1 53  ? 225.955 179.853 172.167 1.00 48.98  ? 53  LYS D CE    1 
ATOM   5854  N  NZ    . LYS D 1 53  ? 227.413 179.958 172.049 1.00 51.29  ? 53  LYS D NZ    1 
ATOM   5855  N  N     . LEU D 1 54  ? 226.436 176.899 177.370 1.00 30.05  ? 54  LEU D N     1 
ATOM   5856  C  CA    . LEU D 1 54  ? 227.123 177.717 178.357 1.00 29.47  ? 54  LEU D CA    1 
ATOM   5857  C  C     . LEU D 1 54  ? 228.075 176.906 179.230 1.00 28.50  ? 54  LEU D C     1 
ATOM   5858  O  O     . LEU D 1 54  ? 228.846 177.490 179.993 1.00 30.46  ? 54  LEU D O     1 
ATOM   5859  C  CB    . LEU D 1 54  ? 226.105 178.468 179.209 1.00 29.96  ? 54  LEU D CB    1 
ATOM   5860  C  CG    . LEU D 1 54  ? 225.490 179.700 178.550 1.00 30.85  ? 54  LEU D CG    1 
ATOM   5861  C  CD1   . LEU D 1 54  ? 224.445 180.360 179.433 1.00 31.69  ? 54  LEU D CD1   1 
ATOM   5862  C  CD2   . LEU D 1 54  ? 226.593 180.687 178.238 1.00 32.64  ? 54  LEU D CD2   1 
ATOM   5863  N  N     . GLY D 1 55  ? 228.006 175.571 179.171 1.00 28.34  ? 55  GLY D N     1 
ATOM   5864  C  CA    . GLY D 1 55  ? 228.967 174.719 179.858 1.00 28.23  ? 55  GLY D CA    1 
ATOM   5865  C  C     . GLY D 1 55  ? 228.410 174.116 181.141 1.00 29.05  ? 55  GLY D C     1 
ATOM   5866  O  O     . GLY D 1 55  ? 227.207 174.135 181.383 1.00 31.12  ? 55  GLY D O     1 
ATOM   5867  N  N     . ASN D 1 56  ? 229.316 173.580 181.960 1.00 30.35  ? 56  ASN D N     1 
ATOM   5868  C  CA    . ASN D 1 56  ? 228.941 172.808 183.131 1.00 31.02  ? 56  ASN D CA    1 
ATOM   5869  C  C     . ASN D 1 56  ? 228.379 173.683 184.244 1.00 28.11  ? 56  ASN D C     1 
ATOM   5870  O  O     . ASN D 1 56  ? 227.593 173.213 185.056 1.00 28.57  ? 56  ASN D O     1 
ATOM   5871  C  CB    . ASN D 1 56  ? 230.113 172.005 183.674 1.00 37.05  ? 56  ASN D CB    1 
ATOM   5872  C  CG    . ASN D 1 56  ? 230.458 170.827 182.795 1.00 43.86  ? 56  ASN D CG    1 
ATOM   5873  O  OD1   . ASN D 1 56  ? 229.657 170.397 181.953 1.00 45.62  ? 56  ASN D OD1   1 
ATOM   5874  N  ND2   . ASN D 1 56  ? 231.638 170.264 183.004 1.00 48.80  ? 56  ASN D ND2   1 
ATOM   5875  N  N     . ASN D 1 57  ? 228.719 174.974 184.246 1.00 27.21  ? 57  ASN D N     1 
ATOM   5876  C  CA    . ASN D 1 57  ? 228.241 175.884 185.279 1.00 26.46  ? 57  ASN D CA    1 
ATOM   5877  C  C     . ASN D 1 57  ? 226.865 176.457 184.943 1.00 23.91  ? 57  ASN D C     1 
ATOM   5878  O  O     . ASN D 1 57  ? 226.437 177.410 185.581 1.00 25.14  ? 57  ASN D O     1 
ATOM   5879  C  CB    . ASN D 1 57  ? 229.246 177.005 185.510 1.00 28.54  ? 57  ASN D CB    1 
ATOM   5880  C  CG    . ASN D 1 57  ? 230.463 176.517 186.263 1.00 32.75  ? 57  ASN D CG    1 
ATOM   5881  O  OD1   . ASN D 1 57  ? 231.540 176.388 185.676 1.00 34.88  ? 57  ASN D OD1   1 
ATOM   5882  N  ND2   . ASN D 1 57  ? 230.302 176.205 187.543 1.00 35.21  ? 57  ASN D ND2   1 
ATOM   5883  N  N     . CYS D 1 58  ? 226.174 175.880 183.963 1.00 22.85  ? 58  CYS D N     1 
ATOM   5884  C  CA    . CYS D 1 58  ? 224.839 176.320 183.593 1.00 23.61  ? 58  CYS D CA    1 
ATOM   5885  C  C     . CYS D 1 58  ? 223.941 175.101 183.410 1.00 24.82  ? 58  CYS D C     1 
ATOM   5886  O  O     . CYS D 1 58  ? 224.319 174.151 182.726 1.00 26.79  ? 58  CYS D O     1 
ATOM   5887  C  CB    . CYS D 1 58  ? 224.865 177.154 182.318 1.00 24.42  ? 58  CYS D CB    1 
ATOM   5888  S  SG    . CYS D 1 58  ? 223.307 178.007 181.982 1.00 25.99  ? 58  CYS D SG    1 
ATOM   5889  N  N     . VAL D 1 59  ? 222.750 175.155 184.015 1.00 23.11  ? 59  VAL D N     1 
ATOM   5890  C  CA    . VAL D 1 59  ? 221.758 174.109 183.853 1.00 22.89  ? 59  VAL D CA    1 
ATOM   5891  C  C     . VAL D 1 59  ? 220.420 174.755 183.514 1.00 22.17  ? 59  VAL D C     1 
ATOM   5892  O  O     . VAL D 1 59  ? 220.167 175.912 183.842 1.00 21.60  ? 59  VAL D O     1 
ATOM   5893  C  CB    . VAL D 1 59  ? 221.626 173.208 185.092 1.00 24.14  ? 59  VAL D CB    1 
ATOM   5894  C  CG1   . VAL D 1 59  ? 222.911 172.441 185.370 1.00 25.25  ? 59  VAL D CG1   1 
ATOM   5895  C  CG2   . VAL D 1 59  ? 221.204 173.997 186.316 1.00 23.84  ? 59  VAL D CG2   1 
ATOM   5896  N  N     . PHE D 1 60  ? 219.568 173.975 182.846 1.00 20.94  ? 60  PHE D N     1 
ATOM   5897  C  CA    . PHE D 1 60  ? 218.244 174.417 182.463 1.00 20.01  ? 60  PHE D CA    1 
ATOM   5898  C  C     . PHE D 1 60  ? 217.220 173.836 183.433 1.00 19.98  ? 60  PHE D C     1 
ATOM   5899  O  O     . PHE D 1 60  ? 217.167 172.633 183.635 1.00 21.39  ? 60  PHE D O     1 
ATOM   5900  C  CB    . PHE D 1 60  ? 217.947 173.978 181.032 1.00 20.71  ? 60  PHE D CB    1 
ATOM   5901  C  CG    . PHE D 1 60  ? 216.510 174.237 180.623 1.00 21.06  ? 60  PHE D CG    1 
ATOM   5902  C  CD1   . PHE D 1 60  ? 215.960 175.509 180.722 1.00 21.39  ? 60  PHE D CD1   1 
ATOM   5903  C  CD2   . PHE D 1 60  ? 215.713 173.193 180.179 1.00 21.32  ? 60  PHE D CD2   1 
ATOM   5904  C  CE1   . PHE D 1 60  ? 214.643 175.726 180.343 1.00 21.75  ? 60  PHE D CE1   1 
ATOM   5905  C  CE2   . PHE D 1 60  ? 214.397 173.412 179.807 1.00 21.59  ? 60  PHE D CE2   1 
ATOM   5906  C  CZ    . PHE D 1 60  ? 213.862 174.680 179.880 1.00 21.38  ? 60  PHE D CZ    1 
ATOM   5907  N  N     . ALA D 1 61  ? 216.396 174.715 184.010 1.00 20.10  ? 61  ALA D N     1 
ATOM   5908  C  CA    . ALA D 1 61  ? 215.312 174.312 184.891 1.00 20.39  ? 61  ALA D CA    1 
ATOM   5909  C  C     . ALA D 1 61  ? 213.992 174.708 184.253 1.00 21.05  ? 61  ALA D C     1 
ATOM   5910  O  O     . ALA D 1 61  ? 213.603 175.871 184.311 1.00 22.51  ? 61  ALA D O     1 
ATOM   5911  C  CB    . ALA D 1 61  ? 215.452 174.935 186.260 1.00 20.55  ? 61  ALA D CB    1 
ATOM   5912  N  N     . PRO D 1 62  ? 213.261 173.769 183.615 1.00 21.09  ? 62  PRO D N     1 
ATOM   5913  C  CA    . PRO D 1 62  ? 211.977 174.104 183.008 1.00 22.02  ? 62  PRO D CA    1 
ATOM   5914  C  C     . PRO D 1 62  ? 210.966 174.466 184.088 1.00 21.92  ? 62  PRO D C     1 
ATOM   5915  O  O     . PRO D 1 62  ? 210.760 173.710 185.039 1.00 24.56  ? 62  PRO D O     1 
ATOM   5916  C  CB    . PRO D 1 62  ? 211.580 172.837 182.238 1.00 22.11  ? 62  PRO D CB    1 
ATOM   5917  C  CG    . PRO D 1 62  ? 212.321 171.743 182.964 1.00 22.35  ? 62  PRO D CG    1 
ATOM   5918  C  CD    . PRO D 1 62  ? 213.615 172.353 183.444 1.00 22.24  ? 62  PRO D CD    1 
ATOM   5919  N  N     . ALA D 1 63  ? 210.343 175.633 183.936 1.00 22.15  ? 63  ALA D N     1 
ATOM   5920  C  CA    . ALA D 1 63  ? 209.353 176.082 184.894 1.00 21.68  ? 63  ALA D CA    1 
ATOM   5921  C  C     . ALA D 1 63  ? 208.517 177.191 184.277 1.00 21.70  ? 63  ALA D C     1 
ATOM   5922  O  O     . ALA D 1 63  ? 208.978 177.931 183.412 1.00 22.00  ? 63  ALA D O     1 
ATOM   5923  C  CB    . ALA D 1 63  ? 210.012 176.543 186.178 1.00 21.84  ? 63  ALA D CB    1 
ATOM   5924  N  N     . ASP D 1 64  ? 207.275 177.286 184.754 1.00 23.46  ? 64  ASP D N     1 
ATOM   5925  C  CA    . ASP D 1 64  ? 206.424 178.431 184.505 1.00 23.66  ? 64  ASP D CA    1 
ATOM   5926  C  C     . ASP D 1 64  ? 206.400 179.291 185.768 1.00 20.60  ? 64  ASP D C     1 
ATOM   5927  O  O     . ASP D 1 64  ? 206.051 178.804 186.841 1.00 22.10  ? 64  ASP D O     1 
ATOM   5928  C  CB    . ASP D 1 64  ? 205.031 177.960 184.127 1.00 27.17  ? 64  ASP D CB    1 
ATOM   5929  C  CG    . ASP D 1 64  ? 204.042 179.077 183.845 1.00 32.09  ? 64  ASP D CG    1 
ATOM   5930  O  OD1   . ASP D 1 64  ? 204.513 180.172 183.468 1.00 35.08  ? 64  ASP D OD1   1 
ATOM   5931  O  OD2   . ASP D 1 64  ? 202.848 178.886 184.153 1.00 38.03  ? 64  ASP D OD2   1 
ATOM   5932  N  N     . VAL D 1 65  ? 206.750 180.566 185.630 1.00 19.33  ? 65  VAL D N     1 
ATOM   5933  C  CA    . VAL D 1 65  ? 206.892 181.442 186.783 1.00 18.51  ? 65  VAL D CA    1 
ATOM   5934  C  C     . VAL D 1 65  ? 205.555 181.685 187.476 1.00 18.07  ? 65  VAL D C     1 
ATOM   5935  O  O     . VAL D 1 65  ? 205.533 181.963 188.671 1.00 18.60  ? 65  VAL D O     1 
ATOM   5936  C  CB    . VAL D 1 65  ? 207.535 182.777 186.380 1.00 18.15  ? 65  VAL D CB    1 
ATOM   5937  C  CG1   . VAL D 1 65  ? 208.986 182.561 186.054 1.00 17.81  ? 65  VAL D CG1   1 
ATOM   5938  C  CG2   . VAL D 1 65  ? 206.797 183.455 185.235 1.00 18.30  ? 65  VAL D CG2   1 
ATOM   5939  N  N     . THR D 1 66  ? 204.447 181.546 186.746 1.00 19.70  ? 66  THR D N     1 
ATOM   5940  C  CA    . THR D 1 66  ? 203.126 181.726 187.344 1.00 21.33  ? 66  THR D CA    1 
ATOM   5941  C  C     . THR D 1 66  ? 202.753 180.554 188.253 1.00 21.83  ? 66  THR D C     1 
ATOM   5942  O  O     . THR D 1 66  ? 201.788 180.664 189.002 1.00 22.88  ? 66  THR D O     1 
ATOM   5943  C  CB    . THR D 1 66  ? 202.073 181.900 186.256 1.00 22.29  ? 66  THR D CB    1 
ATOM   5944  O  OG1   . THR D 1 66  ? 201.939 180.681 185.534 1.00 22.49  ? 66  THR D OG1   1 
ATOM   5945  C  CG2   . THR D 1 66  ? 202.446 182.994 185.277 1.00 22.97  ? 66  THR D CG2   1 
ATOM   5946  N  N     . SER D 1 67  ? 203.512 179.448 188.194 1.00 20.24  ? 67  SER D N     1 
ATOM   5947  C  CA    . SER D 1 67  ? 203.200 178.249 188.953 1.00 20.74  ? 67  SER D CA    1 
ATOM   5948  C  C     . SER D 1 67  ? 204.123 178.136 190.159 1.00 19.56  ? 67  SER D C     1 
ATOM   5949  O  O     . SER D 1 67  ? 205.332 178.138 190.001 1.00 20.35  ? 67  SER D O     1 
ATOM   5950  C  CB    . SER D 1 67  ? 203.324 177.030 188.077 1.00 21.07  ? 67  SER D CB    1 
ATOM   5951  O  OG    . SER D 1 67  ? 203.205 175.835 188.831 1.00 23.02  ? 67  SER D OG    1 
ATOM   5952  N  N     . GLU D 1 68  ? 203.540 178.032 191.353 1.00 19.48  ? 68  GLU D N     1 
ATOM   5953  C  CA    . GLU D 1 68  ? 204.312 177.847 192.571 1.00 20.74  ? 68  GLU D CA    1 
ATOM   5954  C  C     . GLU D 1 68  ? 205.083 176.529 192.514 1.00 21.71  ? 68  GLU D C     1 
ATOM   5955  O  O     . GLU D 1 68  ? 206.253 176.476 192.889 1.00 20.82  ? 68  GLU D O     1 
ATOM   5956  C  CB    . GLU D 1 68  ? 203.398 177.900 193.790 1.00 22.72  ? 68  GLU D CB    1 
ATOM   5957  C  CG    . GLU D 1 68  ? 203.971 177.233 195.037 1.00 26.26  ? 68  GLU D CG    1 
ATOM   5958  C  CD    . GLU D 1 68  ? 203.324 177.687 196.324 1.00 31.84  ? 68  GLU D CD    1 
ATOM   5959  O  OE1   . GLU D 1 68  ? 202.379 178.504 196.241 1.00 35.29  ? 68  GLU D OE1   1 
ATOM   5960  O  OE2   . GLU D 1 68  ? 203.804 177.280 197.399 1.00 39.71  ? 68  GLU D OE2   1 
ATOM   5961  N  N     . LYS D 1 69  ? 204.427 175.459 192.063 1.00 22.63  ? 69  LYS D N     1 
ATOM   5962  C  CA    . LYS D 1 69  ? 205.064 174.151 192.032 1.00 25.41  ? 69  LYS D CA    1 
ATOM   5963  C  C     . LYS D 1 69  ? 206.232 174.132 191.044 1.00 24.03  ? 69  LYS D C     1 
ATOM   5964  O  O     . LYS D 1 69  ? 207.275 173.555 191.337 1.00 24.55  ? 69  LYS D O     1 
ATOM   5965  C  CB    . LYS D 1 69  ? 204.047 173.067 191.669 1.00 30.89  ? 69  LYS D CB    1 
ATOM   5966  C  CG    . LYS D 1 69  ? 204.549 171.657 191.931 1.00 38.24  ? 69  LYS D CG    1 
ATOM   5967  C  CD    . LYS D 1 69  ? 203.480 170.582 191.763 1.00 45.36  ? 69  LYS D CD    1 
ATOM   5968  C  CE    . LYS D 1 69  ? 202.800 170.608 190.423 1.00 49.31  ? 69  LYS D CE    1 
ATOM   5969  N  NZ    . LYS D 1 69  ? 203.773 170.757 189.337 1.00 51.46  ? 69  LYS D NZ    1 
ATOM   5970  N  N     . ASP D 1 70  ? 206.066 174.765 189.876 1.00 22.73  ? 70  ASP D N     1 
ATOM   5971  C  CA    . ASP D 1 70  ? 207.119 174.810 188.875 1.00 23.28  ? 70  ASP D CA    1 
ATOM   5972  C  C     . ASP D 1 70  ? 208.360 175.522 189.413 1.00 20.53  ? 70  ASP D C     1 
ATOM   5973  O  O     . ASP D 1 70  ? 209.473 175.051 189.226 1.00 18.97  ? 70  ASP D O     1 
ATOM   5974  C  CB    . ASP D 1 70  ? 206.636 175.466 187.592 1.00 26.08  ? 70  ASP D CB    1 
ATOM   5975  C  CG    . ASP D 1 70  ? 205.921 174.511 186.653 1.00 32.94  ? 70  ASP D CG    1 
ATOM   5976  O  OD1   . ASP D 1 70  ? 205.874 173.294 186.984 1.00 39.15  ? 70  ASP D OD1   1 
ATOM   5977  O  OD2   . ASP D 1 70  ? 205.410 174.967 185.606 1.00 35.18  ? 70  ASP D OD2   1 
ATOM   5978  N  N     . VAL D 1 71  ? 208.172 176.660 190.081 1.00 18.58  ? 71  VAL D N     1 
ATOM   5979  C  CA    . VAL D 1 71  ? 209.302 177.413 190.602 1.00 17.26  ? 71  VAL D CA    1 
ATOM   5980  C  C     . VAL D 1 71  ? 209.955 176.644 191.742 1.00 17.73  ? 71  VAL D C     1 
ATOM   5981  O  O     . VAL D 1 71  ? 211.177 176.634 191.858 1.00 17.73  ? 71  VAL D O     1 
ATOM   5982  C  CB    . VAL D 1 71  ? 208.874 178.827 191.038 1.00 16.47  ? 71  VAL D CB    1 
ATOM   5983  C  CG1   . VAL D 1 71  ? 210.010 179.579 191.719 1.00 15.80  ? 71  VAL D CG1   1 
ATOM   5984  C  CG2   . VAL D 1 71  ? 208.355 179.613 189.842 1.00 16.04  ? 71  VAL D CG2   1 
ATOM   5985  N  N     . GLN D 1 72  ? 209.148 176.002 192.591 1.00 19.97  ? 72  GLN D N     1 
ATOM   5986  C  CA    . GLN D 1 72  ? 209.691 175.201 193.682 1.00 21.00  ? 72  GLN D CA    1 
ATOM   5987  C  C     . GLN D 1 72  ? 210.569 174.078 193.130 1.00 20.03  ? 72  GLN D C     1 
ATOM   5988  O  O     . GLN D 1 72  ? 211.633 173.798 193.670 1.00 21.16  ? 72  GLN D O     1 
ATOM   5989  C  CB    . GLN D 1 72  ? 208.582 174.644 194.568 1.00 22.68  ? 72  GLN D CB    1 
ATOM   5990  C  CG    . GLN D 1 72  ? 207.953 175.675 195.500 1.00 25.70  ? 72  GLN D CG    1 
ATOM   5991  C  CD    . GLN D 1 72  ? 206.777 175.116 196.275 1.00 28.38  ? 72  GLN D CD    1 
ATOM   5992  O  OE1   . GLN D 1 72  ? 206.046 174.232 195.808 1.00 29.32  ? 72  GLN D OE1   1 
ATOM   5993  N  NE2   . GLN D 1 72  ? 206.575 175.630 197.479 1.00 29.64  ? 72  GLN D NE2   1 
ATOM   5994  N  N     . THR D 1 73  ? 210.118 173.416 192.066 1.00 21.10  ? 73  THR D N     1 
ATOM   5995  C  CA    . THR D 1 73  ? 210.900 172.359 191.437 1.00 22.00  ? 73  THR D CA    1 
ATOM   5996  C  C     . THR D 1 73  ? 212.195 172.929 190.851 1.00 22.44  ? 73  THR D C     1 
ATOM   5997  O  O     . THR D 1 73  ? 213.247 172.320 190.976 1.00 22.55  ? 73  THR D O     1 
ATOM   5998  C  CB    . THR D 1 73  ? 210.074 171.668 190.352 1.00 24.09  ? 73  THR D CB    1 
ATOM   5999  O  OG1   . THR D 1 73  ? 208.922 171.101 190.971 1.00 24.87  ? 73  THR D OG1   1 
ATOM   6000  C  CG2   . THR D 1 73  ? 210.853 170.576 189.648 1.00 25.26  ? 73  THR D CG2   1 
ATOM   6001  N  N     . ALA D 1 74  ? 212.118 174.097 190.204 1.00 21.35  ? 74  ALA D N     1 
ATOM   6002  C  CA    . ALA D 1 74  ? 213.295 174.718 189.613 1.00 21.22  ? 74  ALA D CA    1 
ATOM   6003  C  C     . ALA D 1 74  ? 214.308 175.102 190.687 1.00 20.27  ? 74  ALA D C     1 
ATOM   6004  O  O     . ALA D 1 74  ? 215.508 174.900 190.511 1.00 21.49  ? 74  ALA D O     1 
ATOM   6005  C  CB    . ALA D 1 74  ? 212.894 175.914 188.776 1.00 21.57  ? 74  ALA D CB    1 
ATOM   6006  N  N     . LEU D 1 75  ? 213.838 175.669 191.802 1.00 20.09  ? 75  LEU D N     1 
ATOM   6007  C  CA    . LEU D 1 75  ? 214.738 176.062 192.873 1.00 19.77  ? 75  LEU D CA    1 
ATOM   6008  C  C     . LEU D 1 75  ? 215.346 174.831 193.544 1.00 19.66  ? 75  LEU D C     1 
ATOM   6009  O  O     . LEU D 1 75  ? 216.492 174.868 193.980 1.00 19.38  ? 75  LEU D O     1 
ATOM   6010  C  CB    . LEU D 1 75  ? 214.024 176.950 193.886 1.00 20.14  ? 75  LEU D CB    1 
ATOM   6011  C  CG    . LEU D 1 75  ? 213.555 178.311 193.376 1.00 20.09  ? 75  LEU D CG    1 
ATOM   6012  C  CD1   . LEU D 1 75  ? 212.811 179.061 194.472 1.00 20.72  ? 75  LEU D CD1   1 
ATOM   6013  C  CD2   . LEU D 1 75  ? 214.715 179.117 192.852 1.00 20.59  ? 75  LEU D CD2   1 
ATOM   6014  N  N     . ALA D 1 76  ? 214.580 173.747 193.649 1.00 21.00  ? 76  ALA D N     1 
ATOM   6015  C  CA    . ALA D 1 76  ? 215.109 172.492 194.175 1.00 21.33  ? 76  ALA D CA    1 
ATOM   6016  C  C     . ALA D 1 76  ? 216.206 171.958 193.259 1.00 21.86  ? 76  ALA D C     1 
ATOM   6017  O  O     . ALA D 1 76  ? 217.215 171.442 193.731 1.00 23.24  ? 76  ALA D O     1 
ATOM   6018  C  CB    . ALA D 1 76  ? 214.001 171.478 194.350 1.00 20.92  ? 76  ALA D CB    1 
ATOM   6019  N  N     . LEU D 1 77  ? 216.013 172.086 191.944 1.00 24.61  ? 77  LEU D N     1 
ATOM   6020  C  CA    . LEU D 1 77  ? 217.031 171.683 190.984 1.00 26.51  ? 77  LEU D CA    1 
ATOM   6021  C  C     . LEU D 1 77  ? 218.282 172.542 191.157 1.00 26.55  ? 77  LEU D C     1 
ATOM   6022  O  O     . LEU D 1 77  ? 219.398 172.025 191.116 1.00 25.58  ? 77  LEU D O     1 
ATOM   6023  C  CB    . LEU D 1 77  ? 216.457 171.778 189.570 1.00 29.74  ? 77  LEU D CB    1 
ATOM   6024  C  CG    . LEU D 1 77  ? 217.312 171.253 188.410 1.00 34.16  ? 77  LEU D CG    1 
ATOM   6025  C  CD1   . LEU D 1 77  ? 216.415 170.755 187.297 1.00 36.34  ? 77  LEU D CD1   1 
ATOM   6026  C  CD2   . LEU D 1 77  ? 218.218 172.318 187.849 1.00 35.75  ? 77  LEU D CD2   1 
ATOM   6027  N  N     . ALA D 1 78  ? 218.096 173.856 191.346 1.00 26.30  ? 78  ALA D N     1 
ATOM   6028  C  CA    . ALA D 1 78  ? 219.220 174.762 191.537 1.00 24.94  ? 78  ALA D CA    1 
ATOM   6029  C  C     . ALA D 1 78  ? 219.991 174.399 192.802 1.00 26.08  ? 78  ALA D C     1 
ATOM   6030  O  O     . ALA D 1 78  ? 221.218 174.390 192.802 1.00 26.93  ? 78  ALA D O     1 
ATOM   6031  C  CB    . ALA D 1 78  ? 218.751 176.204 191.585 1.00 25.31  ? 78  ALA D CB    1 
ATOM   6032  N  N     . LYS D 1 79  ? 219.271 174.119 193.889 1.00 28.69  ? 79  LYS D N     1 
ATOM   6033  C  CA    . LYS D 1 79  ? 219.907 173.763 195.145 1.00 31.23  ? 79  LYS D CA    1 
ATOM   6034  C  C     . LYS D 1 79  ? 220.635 172.425 195.014 1.00 30.90  ? 79  LYS D C     1 
ATOM   6035  O  O     . LYS D 1 79  ? 221.732 172.260 195.542 1.00 31.36  ? 79  LYS D O     1 
ATOM   6036  C  CB    . LYS D 1 79  ? 218.872 173.689 196.268 1.00 35.81  ? 79  LYS D CB    1 
ATOM   6037  C  CG    . LYS D 1 79  ? 219.484 173.643 197.648 1.00 41.71  ? 79  LYS D CG    1 
ATOM   6038  C  CD    . LYS D 1 79  ? 219.761 175.053 198.165 1.00 49.99  ? 79  LYS D CD    1 
ATOM   6039  C  CE    . LYS D 1 79  ? 219.930 175.128 199.658 1.00 54.94  ? 79  LYS D CE    1 
ATOM   6040  N  NZ    . LYS D 1 79  ? 220.612 176.361 200.070 1.00 55.59  ? 79  LYS D NZ    1 
ATOM   6041  N  N     . GLY D 1 80  ? 220.032 171.461 194.314 1.00 30.19  ? 80  GLY D N     1 
ATOM   6042  C  CA    . GLY D 1 80  ? 220.663 170.163 194.137 1.00 29.92  ? 80  GLY D CA    1 
ATOM   6043  C  C     . GLY D 1 80  ? 221.948 170.252 193.319 1.00 30.80  ? 80  GLY D C     1 
ATOM   6044  O  O     . GLY D 1 80  ? 222.946 169.613 193.640 1.00 33.42  ? 80  GLY D O     1 
ATOM   6045  N  N     . LYS D 1 81  ? 221.926 171.045 192.247 1.00 30.00  ? 81  LYS D N     1 
ATOM   6046  C  CA    . LYS D 1 81  ? 223.059 171.119 191.339 1.00 29.18  ? 81  LYS D CA    1 
ATOM   6047  C  C     . LYS D 1 81  ? 224.195 171.958 191.930 1.00 27.31  ? 81  LYS D C     1 
ATOM   6048  O  O     . LYS D 1 81  ? 225.355 171.586 191.814 1.00 26.87  ? 81  LYS D O     1 
ATOM   6049  C  CB    . LYS D 1 81  ? 222.604 171.689 189.994 1.00 31.87  ? 81  LYS D CB    1 
ATOM   6050  C  CG    . LYS D 1 81  ? 223.717 171.924 189.007 1.00 36.06  ? 81  LYS D CG    1 
ATOM   6051  C  CD    . LYS D 1 81  ? 224.401 170.637 188.576 1.00 39.53  ? 81  LYS D CD    1 
ATOM   6052  C  CE    . LYS D 1 81  ? 225.448 170.884 187.543 1.00 42.95  ? 81  LYS D CE    1 
ATOM   6053  N  NZ    . LYS D 1 81  ? 226.020 169.638 187.024 1.00 45.32  ? 81  LYS D NZ    1 
ATOM   6054  N  N     . PHE D 1 82  ? 223.864 173.106 192.536 1.00 26.23  ? 82  PHE D N     1 
ATOM   6055  C  CA    . PHE D 1 82  ? 224.879 174.079 192.921 1.00 23.72  ? 82  PHE D CA    1 
ATOM   6056  C  C     . PHE D 1 82  ? 224.937 174.351 194.421 1.00 21.99  ? 82  PHE D C     1 
ATOM   6057  O  O     . PHE D 1 82  ? 225.867 175.014 194.867 1.00 23.55  ? 82  PHE D O     1 
ATOM   6058  C  CB    . PHE D 1 82  ? 224.633 175.401 192.197 1.00 23.68  ? 82  PHE D CB    1 
ATOM   6059  C  CG    . PHE D 1 82  ? 224.824 175.312 190.698 1.00 22.90  ? 82  PHE D CG    1 
ATOM   6060  C  CD1   . PHE D 1 82  ? 226.006 174.829 190.156 1.00 23.48  ? 82  PHE D CD1   1 
ATOM   6061  C  CD2   . PHE D 1 82  ? 223.807 175.696 189.840 1.00 22.82  ? 82  PHE D CD2   1 
ATOM   6062  C  CE1   . PHE D 1 82  ? 226.171 174.750 188.783 1.00 24.29  ? 82  PHE D CE1   1 
ATOM   6063  C  CE2   . PHE D 1 82  ? 223.978 175.616 188.469 1.00 23.32  ? 82  PHE D CE2   1 
ATOM   6064  C  CZ    . PHE D 1 82  ? 225.159 175.143 187.939 1.00 23.97  ? 82  PHE D CZ    1 
ATOM   6065  N  N     . GLY D 1 83  ? 223.957 173.885 195.201 1.00 22.01  ? 83  GLY D N     1 
ATOM   6066  C  CA    . GLY D 1 83  ? 224.066 173.908 196.651 1.00 22.22  ? 83  GLY D CA    1 
ATOM   6067  C  C     . GLY D 1 83  ? 223.429 175.137 197.298 1.00 22.31  ? 83  GLY D C     1 
ATOM   6068  O  O     . GLY D 1 83  ? 223.175 175.126 198.497 1.00 22.48  ? 83  GLY D O     1 
ATOM   6069  N  N     . ARG D 1 84  ? 223.196 176.202 196.525 1.00 21.03  ? 84  ARG D N     1 
ATOM   6070  C  CA    . ARG D 1 84  ? 222.699 177.445 197.088 1.00 20.04  ? 84  ARG D CA    1 
ATOM   6071  C  C     . ARG D 1 84  ? 222.204 178.336 195.952 1.00 18.48  ? 84  ARG D C     1 
ATOM   6072  O  O     . ARG D 1 84  ? 222.421 178.049 194.777 1.00 18.97  ? 84  ARG D O     1 
ATOM   6073  C  CB    . ARG D 1 84  ? 223.789 178.176 197.878 1.00 21.08  ? 84  ARG D CB    1 
ATOM   6074  C  CG    . ARG D 1 84  ? 224.987 178.576 197.028 1.00 22.84  ? 84  ARG D CG    1 
ATOM   6075  C  CD    . ARG D 1 84  ? 226.134 179.102 197.844 1.00 24.36  ? 84  ARG D CD    1 
ATOM   6076  N  NE    . ARG D 1 84  ? 225.837 180.427 198.399 1.00 25.17  ? 84  ARG D NE    1 
ATOM   6077  C  CZ    . ARG D 1 84  ? 226.135 180.838 199.615 1.00 25.65  ? 84  ARG D CZ    1 
ATOM   6078  N  NH1   . ARG D 1 84  ? 226.723 180.031 200.479 1.00 27.54  ? 84  ARG D NH1   1 
ATOM   6079  N  NH2   . ARG D 1 84  ? 225.865 182.073 199.976 1.00 25.35  ? 84  ARG D NH2   1 
ATOM   6080  N  N     . VAL D 1 85  ? 221.520 179.416 196.338 1.00 17.03  ? 85  VAL D N     1 
ATOM   6081  C  CA    . VAL D 1 85  ? 221.145 180.471 195.420 1.00 15.56  ? 85  VAL D CA    1 
ATOM   6082  C  C     . VAL D 1 85  ? 221.596 181.797 196.019 1.00 14.99  ? 85  VAL D C     1 
ATOM   6083  O  O     . VAL D 1 85  ? 221.254 182.116 197.151 1.00 14.83  ? 85  VAL D O     1 
ATOM   6084  C  CB    . VAL D 1 85  ? 219.633 180.486 195.140 1.00 16.42  ? 85  VAL D CB    1 
ATOM   6085  C  CG1   . VAL D 1 85  ? 219.280 181.626 194.198 1.00 16.22  ? 85  VAL D CG1   1 
ATOM   6086  C  CG2   . VAL D 1 85  ? 219.157 179.174 194.544 1.00 16.24  ? 85  VAL D CG2   1 
ATOM   6087  N  N     . ASP D 1 86  ? 222.358 182.577 195.244 1.00 13.97  ? 86  ASP D N     1 
ATOM   6088  C  CA    . ASP D 1 86  ? 222.867 183.861 195.691 1.00 13.39  ? 86  ASP D CA    1 
ATOM   6089  C  C     . ASP D 1 86  ? 222.187 185.024 194.968 1.00 11.80  ? 86  ASP D C     1 
ATOM   6090  O  O     . ASP D 1 86  ? 222.060 186.101 195.544 1.00 11.24  ? 86  ASP D O     1 
ATOM   6091  C  CB    . ASP D 1 86  ? 224.366 183.952 195.469 1.00 15.27  ? 86  ASP D CB    1 
ATOM   6092  C  CG    . ASP D 1 86  ? 225.137 182.867 196.205 1.00 17.66  ? 86  ASP D CG    1 
ATOM   6093  O  OD1   . ASP D 1 86  ? 225.029 182.815 197.456 1.00 19.40  ? 86  ASP D OD1   1 
ATOM   6094  O  OD2   . ASP D 1 86  ? 225.779 182.043 195.522 1.00 19.11  ? 86  ASP D OD2   1 
ATOM   6095  N  N     . VAL D 1 87  ? 221.807 184.824 193.704 1.00 10.82  ? 87  VAL D N     1 
ATOM   6096  C  CA    . VAL D 1 87  ? 221.262 185.890 192.883 1.00 10.34  ? 87  VAL D CA    1 
ATOM   6097  C  C     . VAL D 1 87  ? 220.017 185.364 192.180 1.00 10.05  ? 87  VAL D C     1 
ATOM   6098  O  O     . VAL D 1 87  ? 220.006 184.238 191.693 1.00 9.87   ? 87  VAL D O     1 
ATOM   6099  C  CB    . VAL D 1 87  ? 222.300 186.394 191.862 1.00 10.15  ? 87  VAL D CB    1 
ATOM   6100  C  CG1   . VAL D 1 87  ? 221.719 187.443 190.932 1.00 10.15  ? 87  VAL D CG1   1 
ATOM   6101  C  CG2   . VAL D 1 87  ? 223.546 186.926 192.551 1.00 10.71  ? 87  VAL D CG2   1 
ATOM   6102  N  N     . ALA D 1 88  ? 218.979 186.208 192.122 1.00 9.22   ? 88  ALA D N     1 
ATOM   6103  C  CA    . ALA D 1 88  ? 217.819 185.940 191.296 1.00 9.09   ? 88  ALA D CA    1 
ATOM   6104  C  C     . ALA D 1 88  ? 217.641 187.108 190.333 1.00 8.84   ? 88  ALA D C     1 
ATOM   6105  O  O     . ALA D 1 88  ? 217.613 188.261 190.762 1.00 8.98   ? 88  ALA D O     1 
ATOM   6106  C  CB    . ALA D 1 88  ? 216.577 185.718 192.144 1.00 9.10   ? 88  ALA D CB    1 
ATOM   6107  N  N     . VAL D 1 89  ? 217.534 186.793 189.044 1.00 8.88   ? 89  VAL D N     1 
ATOM   6108  C  CA    . VAL D 1 89  ? 217.275 187.786 188.022 1.00 9.59   ? 89  VAL D CA    1 
ATOM   6109  C  C     . VAL D 1 89  ? 215.967 187.427 187.325 1.00 10.59  ? 89  VAL D C     1 
ATOM   6110  O  O     . VAL D 1 89  ? 215.870 186.392 186.660 1.00 11.22  ? 89  VAL D O     1 
ATOM   6111  C  CB    . VAL D 1 89  ? 218.431 187.880 187.020 1.00 9.80   ? 89  VAL D CB    1 
ATOM   6112  C  CG1   . VAL D 1 89  ? 218.219 189.048 186.078 1.00 10.32  ? 89  VAL D CG1   1 
ATOM   6113  C  CG2   . VAL D 1 89  ? 219.780 187.972 187.715 1.00 9.88   ? 89  VAL D CG2   1 
ATOM   6114  N  N     . ASN D 1 90  ? 214.962 188.293 187.480 1.00 11.26  ? 90  ASN D N     1 
ATOM   6115  C  CA    . ASN D 1 90  ? 213.661 188.085 186.877 1.00 12.43  ? 90  ASN D CA    1 
ATOM   6116  C  C     . ASN D 1 90  ? 213.623 188.753 185.511 1.00 13.92  ? 90  ASN D C     1 
ATOM   6117  O  O     . ASN D 1 90  ? 213.476 189.968 185.426 1.00 14.62  ? 90  ASN D O     1 
ATOM   6118  C  CB    . ASN D 1 90  ? 212.545 188.623 187.770 1.00 12.72  ? 90  ASN D CB    1 
ATOM   6119  C  CG    . ASN D 1 90  ? 212.336 187.780 189.003 1.00 12.94  ? 90  ASN D CG    1 
ATOM   6120  O  OD1   . ASN D 1 90  ? 211.862 186.639 188.903 1.00 14.68  ? 90  ASN D OD1   1 
ATOM   6121  N  ND2   . ASN D 1 90  ? 212.687 188.305 190.170 1.00 13.19  ? 90  ASN D ND2   1 
ATOM   6122  N  N     . CYS D 1 91  ? 213.740 187.958 184.442 1.00 15.70  ? 91  CYS D N     1 
ATOM   6123  C  CA    . CYS D 1 91  ? 213.708 188.496 183.087 1.00 18.08  ? 91  CYS D CA    1 
ATOM   6124  C  C     . CYS D 1 91  ? 212.582 187.904 182.238 1.00 20.30  ? 91  CYS D C     1 
ATOM   6125  O  O     . CYS D 1 91  ? 212.476 188.228 181.056 1.00 24.45  ? 91  CYS D O     1 
ATOM   6126  C  CB    . CYS D 1 91  ? 215.016 188.234 182.347 1.00 19.57  ? 91  CYS D CB    1 
ATOM   6127  S  SG    . CYS D 1 91  ? 216.436 189.109 183.035 1.00 21.12  ? 91  CYS D SG    1 
ATOM   6128  N  N     . ALA D 1 92  ? 211.751 187.025 182.801 1.00 20.29  ? 92  ALA D N     1 
ATOM   6129  C  CA    . ALA D 1 92  ? 210.608 186.515 182.057 1.00 20.54  ? 92  ALA D CA    1 
ATOM   6130  C  C     . ALA D 1 92  ? 209.559 187.607 181.933 1.00 22.00  ? 92  ALA D C     1 
ATOM   6131  O  O     . ALA D 1 92  ? 209.282 188.342 182.877 1.00 25.57  ? 92  ALA D O     1 
ATOM   6132  C  CB    . ALA D 1 92  ? 210.028 185.293 182.716 1.00 20.52  ? 92  ALA D CB    1 
ATOM   6133  N  N     . GLY D 1 93  ? 208.947 187.695 180.764 1.00 24.25  ? 93  GLY D N     1 
ATOM   6134  C  CA    . GLY D 1 93  ? 207.911 188.688 180.553 1.00 26.23  ? 93  GLY D CA    1 
ATOM   6135  C  C     . GLY D 1 93  ? 207.234 188.472 179.208 1.00 26.34  ? 93  GLY D C     1 
ATOM   6136  O  O     . GLY D 1 93  ? 207.821 187.872 178.307 1.00 27.63  ? 93  GLY D O     1 
ATOM   6137  N  N     . ILE D 1 94  ? 205.999 188.971 179.103 1.00 26.12  ? 94  ILE D N     1 
ATOM   6138  C  CA    . ILE D 1 94  ? 205.287 189.011 177.842 1.00 27.09  ? 94  ILE D CA    1 
ATOM   6139  C  C     . ILE D 1 94  ? 204.743 190.421 177.661 1.00 29.70  ? 94  ILE D C     1 
ATOM   6140  O  O     . ILE D 1 94  ? 204.595 191.174 178.624 1.00 31.80  ? 94  ILE D O     1 
ATOM   6141  C  CB    . ILE D 1 94  ? 204.162 187.962 177.790 1.00 27.39  ? 94  ILE D CB    1 
ATOM   6142  C  CG1   . ILE D 1 94  ? 203.124 188.197 178.861 1.00 28.18  ? 94  ILE D CG1   1 
ATOM   6143  C  CG2   . ILE D 1 94  ? 204.722 186.550 177.892 1.00 27.44  ? 94  ILE D CG2   1 
ATOM   6144  C  CD1   . ILE D 1 94  ? 201.859 187.368 178.675 1.00 27.54  ? 94  ILE D CD1   1 
ATOM   6145  N  N     . ALA D 1 95  ? 204.386 190.742 176.414 1.00 29.84  ? 95  ALA D N     1 
ATOM   6146  C  CA    . ALA D 1 95  ? 203.736 191.999 176.096 1.00 31.58  ? 95  ALA D CA    1 
ATOM   6147  C  C     . ALA D 1 95  ? 202.538 191.736 175.191 1.00 32.91  ? 95  ALA D C     1 
ATOM   6148  O  O     . ALA D 1 95  ? 202.515 190.771 174.426 1.00 32.76  ? 95  ALA D O     1 
ATOM   6149  C  CB    . ALA D 1 95  ? 204.726 192.932 175.441 1.00 31.97  ? 95  ALA D CB    1 
ATOM   6150  N  N     . VAL D 1 96  ? 201.551 192.627 175.296 1.00 33.45  ? 96  VAL D N     1 
ATOM   6151  C  CA    . VAL D 1 96  ? 200.417 192.646 174.394 1.00 33.66  ? 96  VAL D CA    1 
ATOM   6152  C  C     . VAL D 1 96  ? 200.258 194.072 173.886 1.00 32.86  ? 96  VAL D C     1 
ATOM   6153  O  O     . VAL D 1 96  ? 200.393 195.021 174.649 1.00 38.40  ? 96  VAL D O     1 
ATOM   6154  C  CB    . VAL D 1 96  ? 199.138 192.154 175.094 1.00 37.72  ? 96  VAL D CB    1 
ATOM   6155  C  CG1   . VAL D 1 96  ? 197.885 192.410 174.291 1.00 39.94  ? 96  VAL D CG1   1 
ATOM   6156  C  CG2   . VAL D 1 96  ? 199.246 190.680 175.432 1.00 39.54  ? 96  VAL D CG2   1 
ATOM   6157  N  N     . ALA D 1 97  ? 199.928 194.204 172.600 1.00 30.45  ? 97  ALA D N     1 
ATOM   6158  C  CA    . ALA D 1 97  ? 199.621 195.491 172.005 1.00 28.91  ? 97  ALA D CA    1 
ATOM   6159  C  C     . ALA D 1 97  ? 198.114 195.569 171.799 1.00 26.82  ? 97  ALA D C     1 
ATOM   6160  O  O     . ALA D 1 97  ? 197.570 194.905 170.916 1.00 28.76  ? 97  ALA D O     1 
ATOM   6161  C  CB    . ALA D 1 97  ? 200.384 195.648 170.708 1.00 30.44  ? 97  ALA D CB    1 
ATOM   6162  N  N     . SER D 1 98  ? 197.440 196.313 172.679 1.00 24.30  ? 98  SER D N     1 
ATOM   6163  C  CA    . SER D 1 98  ? 195.994 196.432 172.608 1.00 23.65  ? 98  SER D CA    1 
ATOM   6164  C  C     . SER D 1 98  ? 195.559 197.732 173.266 1.00 22.82  ? 98  SER D C     1 
ATOM   6165  O  O     . SER D 1 98  ? 195.920 197.994 174.408 1.00 21.92  ? 98  SER D O     1 
ATOM   6166  C  CB    . SER D 1 98  ? 195.329 195.249 173.255 1.00 24.42  ? 98  SER D CB    1 
ATOM   6167  O  OG    . SER D 1 98  ? 193.928 195.266 173.031 1.00 25.90  ? 98  SER D OG    1 
ATOM   6168  N  N     . LYS D 1 99  ? 194.788 198.548 172.548 1.00 21.45  ? 99  LYS D N     1 
ATOM   6169  C  CA    . LYS D 1 99  ? 194.255 199.764 173.125 1.00 22.23  ? 99  LYS D CA    1 
ATOM   6170  C  C     . LYS D 1 99  ? 193.196 199.430 174.172 1.00 21.28  ? 99  LYS D C     1 
ATOM   6171  O  O     . LYS D 1 99  ? 192.518 198.411 174.093 1.00 21.80  ? 99  LYS D O     1 
ATOM   6172  C  CB    . LYS D 1 99  ? 193.629 200.654 172.046 1.00 24.62  ? 99  LYS D CB    1 
ATOM   6173  C  CG    . LYS D 1 99  ? 194.624 201.251 171.079 1.00 26.00  ? 99  LYS D CG    1 
ATOM   6174  C  CD    . LYS D 1 99  ? 193.962 202.307 170.201 1.00 28.67  ? 99  LYS D CD    1 
ATOM   6175  C  CE    . LYS D 1 99  ? 194.908 202.904 169.216 1.00 30.36  ? 99  LYS D CE    1 
ATOM   6176  N  NZ    . LYS D 1 99  ? 194.199 203.880 168.387 1.00 33.08  ? 99  LYS D NZ    1 
ATOM   6177  N  N     . THR D 1 100 ? 193.066 200.312 175.167 1.00 20.40  ? 100 THR D N     1 
ATOM   6178  C  CA    . THR D 1 100 ? 192.050 200.164 176.197 1.00 19.97  ? 100 THR D CA    1 
ATOM   6179  C  C     . THR D 1 100 ? 190.671 200.127 175.534 1.00 20.37  ? 100 THR D C     1 
ATOM   6180  O  O     . THR D 1 100 ? 189.838 199.289 175.872 1.00 19.93  ? 100 THR D O     1 
ATOM   6181  C  CB    . THR D 1 100 ? 192.150 201.318 177.199 1.00 20.21  ? 100 THR D CB    1 
ATOM   6182  O  OG1   . THR D 1 100 ? 193.440 201.259 177.808 1.00 21.11  ? 100 THR D OG1   1 
ATOM   6183  C  CG2   . THR D 1 100 ? 191.056 201.239 178.254 1.00 20.68  ? 100 THR D CG2   1 
ATOM   6184  N  N     . TYR D 1 101 ? 190.425 201.077 174.624 1.00 21.30  ? 101 TYR D N     1 
ATOM   6185  C  CA    . TYR D 1 101 ? 189.171 201.133 173.899 1.00 22.58  ? 101 TYR D CA    1 
ATOM   6186  C  C     . TYR D 1 101 ? 189.402 201.896 172.602 1.00 24.69  ? 101 TYR D C     1 
ATOM   6187  O  O     . TYR D 1 101 ? 190.032 202.949 172.603 1.00 24.57  ? 101 TYR D O     1 
ATOM   6188  C  CB    . TYR D 1 101 ? 188.070 201.790 174.731 1.00 22.57  ? 101 TYR D CB    1 
ATOM   6189  C  CG    . TYR D 1 101 ? 186.750 201.890 173.988 1.00 23.67  ? 101 TYR D CG    1 
ATOM   6190  C  CD1   . TYR D 1 101 ? 186.008 200.749 173.710 1.00 24.70  ? 101 TYR D CD1   1 
ATOM   6191  C  CD2   . TYR D 1 101 ? 186.266 203.119 173.548 1.00 24.88  ? 101 TYR D CD2   1 
ATOM   6192  C  CE1   . TYR D 1 101 ? 184.815 200.830 173.008 1.00 25.74  ? 101 TYR D CE1   1 
ATOM   6193  C  CE2   . TYR D 1 101 ? 185.068 203.210 172.859 1.00 25.51  ? 101 TYR D CE2   1 
ATOM   6194  C  CZ    . TYR D 1 101 ? 184.350 202.061 172.581 1.00 25.54  ? 101 TYR D CZ    1 
ATOM   6195  O  OH    . TYR D 1 101 ? 183.171 202.149 171.904 1.00 28.43  ? 101 TYR D OH    1 
ATOM   6196  N  N     . ASN D 1 102 ? 188.872 201.345 171.505 1.00 27.20  ? 102 ASN D N     1 
ATOM   6197  C  CA    . ASN D 1 102 ? 188.962 201.965 170.197 1.00 29.70  ? 102 ASN D CA    1 
ATOM   6198  C  C     . ASN D 1 102 ? 187.553 202.361 169.769 1.00 29.90  ? 102 ASN D C     1 
ATOM   6199  O  O     . ASN D 1 102 ? 186.735 201.493 169.459 1.00 30.82  ? 102 ASN D O     1 
ATOM   6200  C  CB    . ASN D 1 102 ? 189.612 201.020 169.186 1.00 32.12  ? 102 ASN D CB    1 
ATOM   6201  C  CG    . ASN D 1 102 ? 190.038 201.726 167.917 1.00 34.07  ? 102 ASN D CG    1 
ATOM   6202  O  OD1   . ASN D 1 102 ? 189.378 202.672 167.466 1.00 36.19  ? 102 ASN D OD1   1 
ATOM   6203  N  ND2   . ASN D 1 102 ? 191.170 201.327 167.356 1.00 35.84  ? 102 ASN D ND2   1 
ATOM   6204  N  N     . LEU D 1 103 ? 187.268 203.665 169.771 1.00 30.59  ? 103 LEU D N     1 
ATOM   6205  C  CA    . LEU D 1 103 ? 185.935 204.147 169.441 1.00 33.54  ? 103 LEU D CA    1 
ATOM   6206  C  C     . LEU D 1 103 ? 185.580 203.849 167.983 1.00 36.32  ? 103 LEU D C     1 
ATOM   6207  O  O     . LEU D 1 103 ? 184.462 203.432 167.689 1.00 36.50  ? 103 LEU D O     1 
ATOM   6208  C  CB    . LEU D 1 103 ? 185.810 205.639 169.735 1.00 32.57  ? 103 LEU D CB    1 
ATOM   6209  C  CG    . LEU D 1 103 ? 184.451 206.264 169.408 1.00 33.51  ? 103 LEU D CG    1 
ATOM   6210  C  CD1   . LEU D 1 103 ? 183.314 205.592 170.150 1.00 34.23  ? 103 LEU D CD1   1 
ATOM   6211  C  CD2   . LEU D 1 103 ? 184.456 207.749 169.718 1.00 34.17  ? 103 LEU D CD2   1 
ATOM   6212  N  N     . LYS D 1 104 ? 186.531 204.069 167.071 1.00 39.57  ? 104 LYS D N     1 
ATOM   6213  C  CA    . LYS D 1 104 ? 186.278 203.892 165.650 1.00 43.25  ? 104 LYS D CA    1 
ATOM   6214  C  C     . LYS D 1 104 ? 185.911 202.443 165.335 1.00 41.56  ? 104 LYS D C     1 
ATOM   6215  O  O     . LYS D 1 104 ? 184.952 202.190 164.605 1.00 41.66  ? 104 LYS D O     1 
ATOM   6216  C  CB    . LYS D 1 104 ? 187.494 204.333 164.831 1.00 48.55  ? 104 LYS D CB    1 
ATOM   6217  C  CG    . LYS D 1 104 ? 187.833 205.802 164.946 1.00 53.68  ? 104 LYS D CG    1 
ATOM   6218  C  CD    . LYS D 1 104 ? 186.770 206.734 164.377 1.00 57.28  ? 104 LYS D CD    1 
ATOM   6219  C  CE    . LYS D 1 104 ? 187.197 208.166 164.415 1.00 60.71  ? 104 LYS D CE    1 
ATOM   6220  N  NZ    . LYS D 1 104 ? 188.394 208.422 163.604 1.00 60.71  ? 104 LYS D NZ    1 
ATOM   6221  N  N     . LYS D 1 105 ? 186.678 201.497 165.880 1.00 41.47  ? 105 LYS D N     1 
ATOM   6222  C  CA    . LYS D 1 105 ? 186.433 200.087 165.632 1.00 41.45  ? 105 LYS D CA    1 
ATOM   6223  C  C     . LYS D 1 105 ? 185.428 199.490 166.617 1.00 37.55  ? 105 LYS D C     1 
ATOM   6224  O  O     . LYS D 1 105 ? 184.999 198.353 166.425 1.00 38.60  ? 105 LYS D O     1 
ATOM   6225  C  CB    . LYS D 1 105 ? 187.742 199.304 165.714 1.00 46.49  ? 105 LYS D CB    1 
ATOM   6226  C  CG    . LYS D 1 105 ? 188.671 199.528 164.546 1.00 53.32  ? 105 LYS D CG    1 
ATOM   6227  C  CD    . LYS D 1 105 ? 190.009 198.820 164.707 1.00 58.71  ? 105 LYS D CD    1 
ATOM   6228  C  CE    . LYS D 1 105 ? 189.913 197.392 165.176 1.00 63.32  ? 105 LYS D CE    1 
ATOM   6229  N  NZ    . LYS D 1 105 ? 191.237 196.783 165.318 1.00 65.15  ? 105 LYS D NZ    1 
ATOM   6230  N  N     . GLY D 1 106 ? 185.060 200.227 167.671 1.00 34.76  ? 106 GLY D N     1 
ATOM   6231  C  CA    . GLY D 1 106 ? 184.191 199.682 168.703 1.00 33.30  ? 106 GLY D CA    1 
ATOM   6232  C  C     . GLY D 1 106 ? 184.821 198.478 169.405 1.00 33.45  ? 106 GLY D C     1 
ATOM   6233  O  O     . GLY D 1 106 ? 184.130 197.522 169.750 1.00 35.33  ? 106 GLY D O     1 
ATOM   6234  N  N     . GLN D 1 107 ? 186.143 198.530 169.599 1.00 31.84  ? 107 GLN D N     1 
ATOM   6235  C  CA    . GLN D 1 107 ? 186.892 197.412 170.154 1.00 32.77  ? 107 GLN D CA    1 
ATOM   6236  C  C     . GLN D 1 107 ? 187.340 197.759 171.569 1.00 28.23  ? 107 GLN D C     1 
ATOM   6237  O  O     . GLN D 1 107 ? 187.855 198.853 171.814 1.00 27.70  ? 107 GLN D O     1 
ATOM   6238  C  CB    . GLN D 1 107 ? 188.107 197.108 169.279 1.00 35.40  ? 107 GLN D CB    1 
ATOM   6239  C  CG    . GLN D 1 107 ? 188.703 195.723 169.513 1.00 41.98  ? 107 GLN D CG    1 
ATOM   6240  C  CD    . GLN D 1 107 ? 189.830 195.415 168.548 1.00 47.26  ? 107 GLN D CD    1 
ATOM   6241  O  OE1   . GLN D 1 107 ? 190.573 196.318 168.152 1.00 46.62  ? 107 GLN D OE1   1 
ATOM   6242  N  NE2   . GLN D 1 107 ? 189.961 194.152 168.151 1.00 50.24  ? 107 GLN D NE2   1 
ATOM   6243  N  N     . THR D 1 108 ? 187.132 196.810 172.487 1.00 25.15  ? 108 THR D N     1 
ATOM   6244  C  CA    . THR D 1 108 ? 187.489 196.981 173.882 1.00 23.15  ? 108 THR D CA    1 
ATOM   6245  C  C     . THR D 1 108 ? 188.602 195.997 174.227 1.00 19.47  ? 108 THR D C     1 
ATOM   6246  O  O     . THR D 1 108 ? 188.567 194.840 173.819 1.00 20.21  ? 108 THR D O     1 
ATOM   6247  C  CB    . THR D 1 108 ? 186.275 196.771 174.793 1.00 23.77  ? 108 THR D CB    1 
ATOM   6248  O  OG1   . THR D 1 108 ? 185.266 197.712 174.442 1.00 23.22  ? 108 THR D OG1   1 
ATOM   6249  C  CG2   . THR D 1 108 ? 186.633 196.995 176.253 1.00 24.04  ? 108 THR D CG2   1 
ATOM   6250  N  N     . HIS D 1 109 ? 189.569 196.470 175.012 1.00 17.73  ? 109 HIS D N     1 
ATOM   6251  C  CA    . HIS D 1 109 ? 190.628 195.607 175.504 1.00 17.67  ? 109 HIS D CA    1 
ATOM   6252  C  C     . HIS D 1 109 ? 190.009 194.431 176.254 1.00 17.95  ? 109 HIS D C     1 
ATOM   6253  O  O     . HIS D 1 109 ? 189.165 194.626 177.127 1.00 19.55  ? 109 HIS D O     1 
ATOM   6254  C  CB    . HIS D 1 109 ? 191.572 196.400 176.411 1.00 17.29  ? 109 HIS D CB    1 
ATOM   6255  C  CG    . HIS D 1 109 ? 192.862 195.730 176.712 1.00 16.07  ? 109 HIS D CG    1 
ATOM   6256  N  ND1   . HIS D 1 109 ? 192.950 194.478 177.277 1.00 16.06  ? 109 HIS D ND1   1 
ATOM   6257  C  CD2   . HIS D 1 109 ? 194.122 196.155 176.546 1.00 15.79  ? 109 HIS D CD2   1 
ATOM   6258  C  CE1   . HIS D 1 109 ? 194.227 194.155 177.439 1.00 15.97  ? 109 HIS D CE1   1 
ATOM   6259  N  NE2   . HIS D 1 109 ? 194.959 195.161 177.009 1.00 16.76  ? 109 HIS D NE2   1 
ATOM   6260  N  N     . THR D 1 110 ? 190.450 193.222 175.939 1.00 18.32  ? 110 THR D N     1 
ATOM   6261  C  CA    . THR D 1 110 ? 189.916 192.058 176.625 1.00 21.67  ? 110 THR D CA    1 
ATOM   6262  C  C     . THR D 1 110 ? 190.528 191.961 178.021 1.00 21.27  ? 110 THR D C     1 
ATOM   6263  O  O     . THR D 1 110 ? 191.706 192.245 178.212 1.00 20.12  ? 110 THR D O     1 
ATOM   6264  C  CB    . THR D 1 110 ? 190.148 190.781 175.822 1.00 22.72  ? 110 THR D CB    1 
ATOM   6265  O  OG1   . THR D 1 110 ? 191.540 190.512 175.803 1.00 23.63  ? 110 THR D OG1   1 
ATOM   6266  C  CG2   . THR D 1 110 ? 189.596 190.891 174.412 1.00 22.78  ? 110 THR D CG2   1 
ATOM   6267  N  N     . LEU D 1 111 ? 189.712 191.534 178.984 1.00 22.24  ? 111 LEU D N     1 
ATOM   6268  C  CA    . LEU D 1 111 ? 190.165 191.360 180.351 1.00 23.60  ? 111 LEU D CA    1 
ATOM   6269  C  C     . LEU D 1 111 ? 191.211 190.250 180.448 1.00 22.55  ? 111 LEU D C     1 
ATOM   6270  O  O     . LEU D 1 111 ? 192.153 190.363 181.226 1.00 20.10  ? 111 LEU D O     1 
ATOM   6271  C  CB    . LEU D 1 111 ? 188.975 191.074 181.265 1.00 23.52  ? 111 LEU D CB    1 
ATOM   6272  C  CG    . LEU D 1 111 ? 189.255 191.218 182.765 1.00 23.68  ? 111 LEU D CG    1 
ATOM   6273  C  CD1   . LEU D 1 111 ? 189.817 192.593 183.087 1.00 23.45  ? 111 LEU D CD1   1 
ATOM   6274  C  CD2   . LEU D 1 111 ? 187.993 190.960 183.563 1.00 23.57  ? 111 LEU D CD2   1 
ATOM   6275  N  N     . GLU D 1 112 ? 191.048 189.178 179.668 1.00 22.83  ? 112 GLU D N     1 
ATOM   6276  C  CA    . GLU D 1 112 ? 191.969 188.056 179.749 1.00 26.61  ? 112 GLU D CA    1 
ATOM   6277  C  C     . GLU D 1 112 ? 193.364 188.439 179.247 1.00 24.98  ? 112 GLU D C     1 
ATOM   6278  O  O     . GLU D 1 112 ? 194.364 187.960 179.775 1.00 26.45  ? 112 GLU D O     1 
ATOM   6279  C  CB    . GLU D 1 112 ? 191.454 186.808 179.041 1.00 31.78  ? 112 GLU D CB    1 
ATOM   6280  C  CG    . GLU D 1 112 ? 191.318 186.954 177.537 1.00 38.43  ? 112 GLU D CG    1 
ATOM   6281  C  CD    . GLU D 1 112 ? 190.002 187.587 177.108 1.00 48.59  ? 112 GLU D CD    1 
ATOM   6282  O  OE1   . GLU D 1 112 ? 189.255 188.196 177.932 1.00 48.02  ? 112 GLU D OE1   1 
ATOM   6283  O  OE2   . GLU D 1 112 ? 189.702 187.429 175.895 1.00 50.87  ? 112 GLU D OE2   1 
ATOM   6284  N  N     . ASP D 1 113 ? 193.444 189.297 178.237 1.00 22.81  ? 113 ASP D N     1 
ATOM   6285  C  CA    . ASP D 1 113 ? 194.738 189.791 177.781 1.00 23.10  ? 113 ASP D CA    1 
ATOM   6286  C  C     . ASP D 1 113 ? 195.449 190.572 178.885 1.00 20.10  ? 113 ASP D C     1 
ATOM   6287  O  O     . ASP D 1 113 ? 196.653 190.404 179.107 1.00 19.32  ? 113 ASP D O     1 
ATOM   6288  C  CB    . ASP D 1 113 ? 194.609 190.662 176.544 1.00 27.17  ? 113 ASP D CB    1 
ATOM   6289  C  CG    . ASP D 1 113 ? 194.603 189.884 175.241 1.00 30.91  ? 113 ASP D CG    1 
ATOM   6290  O  OD1   . ASP D 1 113 ? 194.664 188.634 175.315 1.00 33.86  ? 113 ASP D OD1   1 
ATOM   6291  O  OD2   . ASP D 1 113 ? 194.539 190.537 174.177 1.00 33.56  ? 113 ASP D OD2   1 
ATOM   6292  N  N     . PHE D 1 114 ? 194.698 191.420 179.591 1.00 17.80  ? 114 PHE D N     1 
ATOM   6293  C  CA    . PHE D 1 114 ? 195.254 192.159 180.713 1.00 16.38  ? 114 PHE D CA    1 
ATOM   6294  C  C     . PHE D 1 114 ? 195.698 191.195 181.812 1.00 16.34  ? 114 PHE D C     1 
ATOM   6295  O  O     . PHE D 1 114 ? 196.751 191.382 182.407 1.00 16.50  ? 114 PHE D O     1 
ATOM   6296  C  CB    . PHE D 1 114 ? 194.211 193.148 181.227 1.00 15.12  ? 114 PHE D CB    1 
ATOM   6297  C  CG    . PHE D 1 114 ? 194.746 194.118 182.259 1.00 15.36  ? 114 PHE D CG    1 
ATOM   6298  C  CD1   . PHE D 1 114 ? 195.396 195.274 181.858 1.00 15.53  ? 114 PHE D CD1   1 
ATOM   6299  C  CD2   . PHE D 1 114 ? 194.588 193.871 183.615 1.00 15.57  ? 114 PHE D CD2   1 
ATOM   6300  C  CE1   . PHE D 1 114 ? 195.875 196.176 182.794 1.00 15.43  ? 114 PHE D CE1   1 
ATOM   6301  C  CE2   . PHE D 1 114 ? 195.071 194.775 184.546 1.00 16.66  ? 114 PHE D CE2   1 
ATOM   6302  C  CZ    . PHE D 1 114 ? 195.720 195.917 184.134 1.00 15.40  ? 114 PHE D CZ    1 
ATOM   6303  N  N     . GLN D 1 115 ? 194.879 190.183 182.105 1.00 18.37  ? 115 GLN D N     1 
ATOM   6304  C  CA    . GLN D 1 115 ? 195.167 189.245 183.179 1.00 20.80  ? 115 GLN D CA    1 
ATOM   6305  C  C     . GLN D 1 115 ? 196.423 188.435 182.864 1.00 19.39  ? 115 GLN D C     1 
ATOM   6306  O  O     . GLN D 1 115 ? 197.259 188.232 183.735 1.00 19.15  ? 115 GLN D O     1 
ATOM   6307  C  CB    . GLN D 1 115 ? 193.975 188.319 183.405 1.00 23.39  ? 115 GLN D CB    1 
ATOM   6308  C  CG    . GLN D 1 115 ? 194.135 187.388 184.602 1.00 27.34  ? 115 GLN D CG    1 
ATOM   6309  C  CD    . GLN D 1 115 ? 194.194 188.134 185.921 1.00 31.16  ? 115 GLN D CD    1 
ATOM   6310  O  OE1   . GLN D 1 115 ? 193.205 188.729 186.366 1.00 31.94  ? 115 GLN D OE1   1 
ATOM   6311  N  NE2   . GLN D 1 115 ? 195.375 188.159 186.528 1.00 32.88  ? 115 GLN D NE2   1 
ATOM   6312  N  N     . ARG D 1 116 ? 196.567 187.983 181.614 1.00 19.54  ? 116 ARG D N     1 
ATOM   6313  C  CA    . ARG D 1 116 ? 197.686 187.131 181.250 1.00 20.27  ? 116 ARG D CA    1 
ATOM   6314  C  C     . ARG D 1 116 ? 199.010 187.886 181.367 1.00 17.25  ? 116 ARG D C     1 
ATOM   6315  O  O     . ARG D 1 116 ? 200.015 187.316 181.765 1.00 17.28  ? 116 ARG D O     1 
ATOM   6316  C  CB    . ARG D 1 116 ? 197.479 186.560 179.844 1.00 23.98  ? 116 ARG D CB    1 
ATOM   6317  C  CG    . ARG D 1 116 ? 198.593 185.631 179.392 1.00 30.61  ? 116 ARG D CG    1 
ATOM   6318  C  CD    . ARG D 1 116 ? 198.348 185.061 178.003 1.00 36.34  ? 116 ARG D CD    1 
ATOM   6319  N  NE    . ARG D 1 116 ? 198.762 186.015 176.968 1.00 40.51  ? 116 ARG D NE    1 
ATOM   6320  C  CZ    . ARG D 1 116 ? 197.942 186.796 176.269 1.00 42.50  ? 116 ARG D CZ    1 
ATOM   6321  N  NH1   . ARG D 1 116 ? 196.633 186.826 176.508 1.00 41.08  ? 116 ARG D NH1   1 
ATOM   6322  N  NH2   . ARG D 1 116 ? 198.453 187.591 175.345 1.00 42.82  ? 116 ARG D NH2   1 
ATOM   6323  N  N     . VAL D 1 117 ? 199.028 189.161 180.995 1.00 16.27  ? 117 VAL D N     1 
ATOM   6324  C  CA    . VAL D 1 117 ? 200.225 189.971 181.135 1.00 16.39  ? 117 VAL D CA    1 
ATOM   6325  C  C     . VAL D 1 117 ? 200.585 190.160 182.611 1.00 16.05  ? 117 VAL D C     1 
ATOM   6326  O  O     . VAL D 1 117 ? 201.746 190.037 182.986 1.00 15.48  ? 117 VAL D O     1 
ATOM   6327  C  CB    . VAL D 1 117 ? 200.069 191.320 180.418 1.00 16.83  ? 117 VAL D CB    1 
ATOM   6328  C  CG1   . VAL D 1 117 ? 201.249 192.238 180.696 1.00 17.10  ? 117 VAL D CG1   1 
ATOM   6329  C  CG2   . VAL D 1 117 ? 199.893 191.120 178.927 1.00 17.06  ? 117 VAL D CG2   1 
ATOM   6330  N  N     . LEU D 1 118 ? 199.592 190.440 183.455 1.00 17.15  ? 118 LEU D N     1 
ATOM   6331  C  CA    . LEU D 1 118 ? 199.840 190.595 184.882 1.00 18.46  ? 118 LEU D CA    1 
ATOM   6332  C  C     . LEU D 1 118 ? 200.381 189.302 185.490 1.00 18.28  ? 118 LEU D C     1 
ATOM   6333  O  O     . LEU D 1 118 ? 201.290 189.348 186.317 1.00 17.82  ? 118 LEU D O     1 
ATOM   6334  C  CB    . LEU D 1 118 ? 198.571 191.005 185.631 1.00 20.58  ? 118 LEU D CB    1 
ATOM   6335  C  CG    . LEU D 1 118 ? 198.119 192.455 185.490 1.00 23.03  ? 118 LEU D CG    1 
ATOM   6336  C  CD1   . LEU D 1 118 ? 196.906 192.623 186.396 1.00 24.94  ? 118 LEU D CD1   1 
ATOM   6337  C  CD2   . LEU D 1 118 ? 199.212 193.436 185.870 1.00 22.60  ? 118 LEU D CD2   1 
ATOM   6338  N  N     . ASP D 1 119 ? 199.809 188.157 185.100 1.00 17.74  ? 119 ASP D N     1 
ATOM   6339  C  CA    . ASP D 1 119 ? 200.192 186.886 185.688 1.00 19.25  ? 119 ASP D CA    1 
ATOM   6340  C  C     . ASP D 1 119 ? 201.669 186.597 185.456 1.00 17.19  ? 119 ASP D C     1 
ATOM   6341  O  O     . ASP D 1 119 ? 202.371 186.171 186.377 1.00 17.75  ? 119 ASP D O     1 
ATOM   6342  C  CB    . ASP D 1 119 ? 199.336 185.752 185.154 1.00 21.92  ? 119 ASP D CB    1 
ATOM   6343  C  CG    . ASP D 1 119 ? 197.877 185.859 185.556 1.00 27.53  ? 119 ASP D CG    1 
ATOM   6344  O  OD1   . ASP D 1 119 ? 197.559 186.793 186.337 1.00 29.16  ? 119 ASP D OD1   1 
ATOM   6345  O  OD2   . ASP D 1 119 ? 197.061 185.094 184.997 1.00 31.33  ? 119 ASP D OD2   1 
ATOM   6346  N  N     . VAL D 1 120 ? 202.140 186.808 184.229 1.00 14.98  ? 120 VAL D N     1 
ATOM   6347  C  CA    . VAL D 1 120 ? 203.513 186.474 183.906 1.00 15.45  ? 120 VAL D CA    1 
ATOM   6348  C  C     . VAL D 1 120 ? 204.451 187.559 184.422 1.00 14.47  ? 120 VAL D C     1 
ATOM   6349  O  O     . VAL D 1 120 ? 205.415 187.265 185.128 1.00 15.11  ? 120 VAL D O     1 
ATOM   6350  C  CB    . VAL D 1 120 ? 203.680 186.227 182.402 1.00 16.72  ? 120 VAL D CB    1 
ATOM   6351  C  CG1   . VAL D 1 120 ? 205.148 186.053 182.032 1.00 18.26  ? 120 VAL D CG1   1 
ATOM   6352  C  CG2   . VAL D 1 120 ? 202.868 185.017 181.960 1.00 16.61  ? 120 VAL D CG2   1 
ATOM   6353  N  N     . ASN D 1 121 ? 204.191 188.811 184.051 1.00 13.35  ? 121 ASN D N     1 
ATOM   6354  C  CA    . ASN D 1 121 ? 205.122 189.890 184.331 1.00 13.27  ? 121 ASN D CA    1 
ATOM   6355  C  C     . ASN D 1 121 ? 205.166 190.198 185.828 1.00 12.99  ? 121 ASN D C     1 
ATOM   6356  O  O     . ASN D 1 121 ? 206.240 190.302 186.415 1.00 13.10  ? 121 ASN D O     1 
ATOM   6357  C  CB    . ASN D 1 121 ? 204.776 191.137 183.529 1.00 13.45  ? 121 ASN D CB    1 
ATOM   6358  C  CG    . ASN D 1 121 ? 204.917 190.915 182.038 1.00 14.34  ? 121 ASN D CG    1 
ATOM   6359  O  OD1   . ASN D 1 121 ? 205.114 189.784 181.584 1.00 16.53  ? 121 ASN D OD1   1 
ATOM   6360  N  ND2   . ASN D 1 121 ? 204.771 191.967 181.253 1.00 15.51  ? 121 ASN D ND2   1 
ATOM   6361  N  N     . LEU D 1 122 ? 203.989 190.367 186.445 1.00 12.19  ? 122 LEU D N     1 
ATOM   6362  C  CA    . LEU D 1 122 ? 203.904 190.892 187.797 1.00 11.63  ? 122 LEU D CA    1 
ATOM   6363  C  C     . LEU D 1 122 ? 203.787 189.762 188.817 1.00 12.19  ? 122 LEU D C     1 
ATOM   6364  O  O     . LEU D 1 122 ? 204.615 189.650 189.719 1.00 11.48  ? 122 LEU D O     1 
ATOM   6365  C  CB    . LEU D 1 122 ? 202.737 191.880 187.909 1.00 11.39  ? 122 LEU D CB    1 
ATOM   6366  C  CG    . LEU D 1 122 ? 202.529 192.523 189.280 1.00 10.90  ? 122 LEU D CG    1 
ATOM   6367  C  CD1   . LEU D 1 122 ? 203.821 193.105 189.819 1.00 10.87  ? 122 LEU D CD1   1 
ATOM   6368  C  CD2   . LEU D 1 122 ? 201.455 193.594 189.188 1.00 11.06  ? 122 LEU D CD2   1 
ATOM   6369  N  N     . MET D 1 123 ? 202.755 188.929 188.684 1.00 13.22  ? 123 MET D N     1 
ATOM   6370  C  CA    . MET D 1 123 ? 202.566 187.838 189.627 1.00 15.00  ? 123 MET D CA    1 
ATOM   6371  C  C     . MET D 1 123 ? 203.708 186.830 189.504 1.00 12.70  ? 123 MET D C     1 
ATOM   6372  O  O     . MET D 1 123 ? 204.159 186.279 190.505 1.00 12.76  ? 123 MET D O     1 
ATOM   6373  C  CB    . MET D 1 123 ? 201.196 187.181 189.432 1.00 18.48  ? 123 MET D CB    1 
ATOM   6374  C  CG    . MET D 1 123 ? 200.878 186.074 190.416 1.00 23.14  ? 123 MET D CG    1 
ATOM   6375  S  SD    . MET D 1 123 ? 201.444 184.460 189.833 1.00 32.57  ? 123 MET D SD    1 
ATOM   6376  C  CE    . MET D 1 123 ? 200.215 184.109 188.571 1.00 32.68  ? 123 MET D CE    1 
ATOM   6377  N  N     . GLY D 1 124 ? 204.167 186.565 188.287 1.00 11.87  ? 124 GLY D N     1 
ATOM   6378  C  CA    . GLY D 1 124 ? 205.270 185.638 188.091 1.00 11.34  ? 124 GLY D CA    1 
ATOM   6379  C  C     . GLY D 1 124 ? 206.553 186.131 188.764 1.00 10.31  ? 124 GLY D C     1 
ATOM   6380  O  O     . GLY D 1 124 ? 207.287 185.357 189.366 1.00 9.99   ? 124 GLY D O     1 
ATOM   6381  N  N     . THR D 1 125 ? 206.818 187.435 188.666 1.00 9.89   ? 125 THR D N     1 
ATOM   6382  C  CA    . THR D 1 125 ? 207.987 188.009 189.313 1.00 10.15  ? 125 THR D CA    1 
ATOM   6383  C  C     . THR D 1 125 ? 207.883 187.839 190.828 1.00 9.16   ? 125 THR D C     1 
ATOM   6384  O  O     . THR D 1 125 ? 208.846 187.445 191.477 1.00 9.83   ? 125 THR D O     1 
ATOM   6385  C  CB    . THR D 1 125 ? 208.151 189.476 188.929 1.00 10.91  ? 125 THR D CB    1 
ATOM   6386  O  OG1   . THR D 1 125 ? 208.618 189.541 187.587 1.00 11.94  ? 125 THR D OG1   1 
ATOM   6387  C  CG2   . THR D 1 125 ? 209.145 190.172 189.832 1.00 11.05  ? 125 THR D CG2   1 
ATOM   6388  N  N     . PHE D 1 126 ? 206.725 188.165 191.399 1.00 8.97   ? 126 PHE D N     1 
ATOM   6389  C  CA    . PHE D 1 126 ? 206.536 188.050 192.836 1.00 9.36   ? 126 PHE D CA    1 
ATOM   6390  C  C     . PHE D 1 126 ? 206.640 186.590 193.279 1.00 9.09   ? 126 PHE D C     1 
ATOM   6391  O  O     . PHE D 1 126 ? 207.174 186.304 194.342 1.00 8.94   ? 126 PHE D O     1 
ATOM   6392  C  CB    . PHE D 1 126 ? 205.190 188.653 193.265 1.00 9.94   ? 126 PHE D CB    1 
ATOM   6393  C  CG    . PHE D 1 126 ? 205.017 188.628 194.770 1.00 10.38  ? 126 PHE D CG    1 
ATOM   6394  C  CD1   . PHE D 1 126 ? 205.712 189.517 195.582 1.00 10.75  ? 126 PHE D CD1   1 
ATOM   6395  C  CD2   . PHE D 1 126 ? 204.200 187.683 195.369 1.00 10.59  ? 126 PHE D CD2   1 
ATOM   6396  C  CE1   . PHE D 1 126 ? 205.568 189.467 196.959 1.00 11.40  ? 126 PHE D CE1   1 
ATOM   6397  C  CE2   . PHE D 1 126 ? 204.048 187.647 196.741 1.00 11.06  ? 126 PHE D CE2   1 
ATOM   6398  C  CZ    . PHE D 1 126 ? 204.732 188.537 197.536 1.00 11.47  ? 126 PHE D CZ    1 
ATOM   6399  N  N     . ASN D 1 127 ? 206.110 185.672 192.470 1.00 9.31   ? 127 ASN D N     1 
ATOM   6400  C  CA    . ASN D 1 127 ? 206.170 184.255 192.792 1.00 10.03  ? 127 ASN D CA    1 
ATOM   6401  C  C     . ASN D 1 127 ? 207.622 183.791 192.911 1.00 9.92   ? 127 ASN D C     1 
ATOM   6402  O  O     . ASN D 1 127 ? 207.973 183.055 193.828 1.00 11.01  ? 127 ASN D O     1 
ATOM   6403  C  CB    . ASN D 1 127 ? 205.405 183.433 191.763 1.00 10.93  ? 127 ASN D CB    1 
ATOM   6404  C  CG    . ASN D 1 127 ? 205.342 181.971 192.130 1.00 12.02  ? 127 ASN D CG    1 
ATOM   6405  O  OD1   . ASN D 1 127 ? 205.097 181.640 193.296 1.00 13.24  ? 127 ASN D OD1   1 
ATOM   6406  N  ND2   . ASN D 1 127 ? 205.557 181.083 191.162 1.00 12.58  ? 127 ASN D ND2   1 
ATOM   6407  N  N     . VAL D 1 128 ? 208.473 184.216 191.984 1.00 9.67   ? 128 VAL D N     1 
ATOM   6408  C  CA    . VAL D 1 128 ? 209.882 183.877 192.055 1.00 9.88   ? 128 VAL D CA    1 
ATOM   6409  C  C     . VAL D 1 128 ? 210.523 184.545 193.270 1.00 9.26   ? 128 VAL D C     1 
ATOM   6410  O  O     . VAL D 1 128 ? 211.273 183.901 194.002 1.00 9.36   ? 128 VAL D O     1 
ATOM   6411  C  CB    . VAL D 1 128 ? 210.604 184.251 190.750 1.00 10.30  ? 128 VAL D CB    1 
ATOM   6412  C  CG1   . VAL D 1 128 ? 212.104 184.037 190.855 1.00 10.72  ? 128 VAL D CG1   1 
ATOM   6413  C  CG2   . VAL D 1 128 ? 210.042 183.458 189.589 1.00 10.52  ? 128 VAL D CG2   1 
ATOM   6414  N  N     . ILE D 1 129 ? 210.222 185.835 193.490 1.00 8.83   ? 129 ILE D N     1 
ATOM   6415  C  CA    . ILE D 1 129 ? 210.842 186.571 194.582 1.00 8.60   ? 129 ILE D CA    1 
ATOM   6416  C  C     . ILE D 1 129 ? 210.541 185.890 195.913 1.00 8.70   ? 129 ILE D C     1 
ATOM   6417  O  O     . ILE D 1 129 ? 211.440 185.664 196.726 1.00 9.24   ? 129 ILE D O     1 
ATOM   6418  C  CB    . ILE D 1 129 ? 210.379 188.041 194.600 1.00 8.68   ? 129 ILE D CB    1 
ATOM   6419  C  CG1   . ILE D 1 129 ? 211.024 188.836 193.471 1.00 8.95   ? 129 ILE D CG1   1 
ATOM   6420  C  CG2   . ILE D 1 129 ? 210.673 188.681 195.956 1.00 8.53   ? 129 ILE D CG2   1 
ATOM   6421  C  CD1   . ILE D 1 129 ? 210.431 190.207 193.271 1.00 9.07   ? 129 ILE D CD1   1 
ATOM   6422  N  N     . ARG D 1 130 ? 209.267 185.600 196.176 1.00 9.03   ? 130 ARG D N     1 
ATOM   6423  C  CA    . ARG D 1 130 ? 208.870 185.088 197.477 1.00 9.45   ? 130 ARG D CA    1 
ATOM   6424  C  C     . ARG D 1 130 ? 209.465 183.701 197.735 1.00 9.79   ? 130 ARG D C     1 
ATOM   6425  O  O     . ARG D 1 130 ? 209.696 183.352 198.887 1.00 10.18  ? 130 ARG D O     1 
ATOM   6426  C  CB    . ARG D 1 130 ? 207.345 185.061 197.608 1.00 9.56   ? 130 ARG D CB    1 
ATOM   6427  C  CG    . ARG D 1 130 ? 206.693 183.821 197.014 1.00 9.45   ? 130 ARG D CG    1 
ATOM   6428  C  CD    . ARG D 1 130 ? 205.239 184.044 196.716 1.00 9.77   ? 130 ARG D CD    1 
ATOM   6429  N  NE    . ARG D 1 130 ? 204.680 182.859 196.062 1.00 10.11  ? 130 ARG D NE    1 
ATOM   6430  C  CZ    . ARG D 1 130 ? 204.359 181.735 196.689 1.00 10.57  ? 130 ARG D CZ    1 
ATOM   6431  N  NH1   . ARG D 1 130 ? 204.359 181.682 198.009 1.00 10.01  ? 130 ARG D NH1   1 
ATOM   6432  N  NH2   . ARG D 1 130 ? 204.005 180.683 195.979 1.00 10.89  ? 130 ARG D NH2   1 
ATOM   6433  N  N     . LEU D 1 131 ? 209.701 182.916 196.681 1.00 10.34  ? 131 LEU D N     1 
ATOM   6434  C  CA    . LEU D 1 131 ? 210.243 181.572 196.834 1.00 10.64  ? 131 LEU D CA    1 
ATOM   6435  C  C     . LEU D 1 131 ? 211.771 181.574 196.887 1.00 11.63  ? 131 LEU D C     1 
ATOM   6436  O  O     . LEU D 1 131 ? 212.358 180.799 197.633 1.00 12.42  ? 131 LEU D O     1 
ATOM   6437  C  CB    . LEU D 1 131 ? 209.731 180.666 195.721 1.00 11.06  ? 131 LEU D CB    1 
ATOM   6438  C  CG    . LEU D 1 131 ? 208.232 180.347 195.799 1.00 11.28  ? 131 LEU D CG    1 
ATOM   6439  C  CD1   . LEU D 1 131 ? 207.770 179.615 194.563 1.00 11.68  ? 131 LEU D CD1   1 
ATOM   6440  C  CD2   . LEU D 1 131 ? 207.887 179.558 197.058 1.00 11.26  ? 131 LEU D CD2   1 
ATOM   6441  N  N     . VAL D 1 132 ? 212.426 182.416 196.089 1.00 12.24  ? 132 VAL D N     1 
ATOM   6442  C  CA    . VAL D 1 132 ? 213.874 182.476 196.120 1.00 13.61  ? 132 VAL D CA    1 
ATOM   6443  C  C     . VAL D 1 132 ? 214.354 183.136 197.413 1.00 13.40  ? 132 VAL D C     1 
ATOM   6444  O  O     . VAL D 1 132 ? 215.465 182.869 197.866 1.00 14.47  ? 132 VAL D O     1 
ATOM   6445  C  CB    . VAL D 1 132 ? 214.438 183.186 194.880 1.00 15.17  ? 132 VAL D CB    1 
ATOM   6446  C  CG1   . VAL D 1 132 ? 214.166 184.678 194.915 1.00 15.84  ? 132 VAL D CG1   1 
ATOM   6447  C  CG2   . VAL D 1 132 ? 215.928 182.922 194.745 1.00 17.80  ? 132 VAL D CG2   1 
ATOM   6448  N  N     . ALA D 1 133 ? 213.548 184.030 197.993 1.00 12.75  ? 133 ALA D N     1 
ATOM   6449  C  CA    . ALA D 1 133 ? 213.898 184.653 199.261 1.00 13.51  ? 133 ALA D CA    1 
ATOM   6450  C  C     . ALA D 1 133 ? 214.065 183.587 200.346 1.00 14.76  ? 133 ALA D C     1 
ATOM   6451  O  O     . ALA D 1 133 ? 214.973 183.678 201.172 1.00 14.95  ? 133 ALA D O     1 
ATOM   6452  C  CB    . ALA D 1 133 ? 212.868 185.684 199.671 1.00 13.13  ? 133 ALA D CB    1 
ATOM   6453  N  N     . GLY D 1 134 ? 213.175 182.591 200.357 1.00 15.84  ? 134 GLY D N     1 
ATOM   6454  C  CA    . GLY D 1 134 ? 213.314 181.468 201.270 1.00 16.82  ? 134 GLY D CA    1 
ATOM   6455  C  C     . GLY D 1 134 ? 214.602 180.687 201.031 1.00 17.56  ? 134 GLY D C     1 
ATOM   6456  O  O     . GLY D 1 134 ? 215.252 180.266 201.983 1.00 20.21  ? 134 GLY D O     1 
ATOM   6457  N  N     . GLU D 1 135 ? 214.971 180.496 199.768 1.00 18.28  ? 135 GLU D N     1 
ATOM   6458  C  CA    . GLU D 1 135 ? 216.208 179.803 199.436 1.00 19.00  ? 135 GLU D CA    1 
ATOM   6459  C  C     . GLU D 1 135 ? 217.410 180.646 199.866 1.00 17.10  ? 135 GLU D C     1 
ATOM   6460  O  O     . GLU D 1 135 ? 218.374 180.118 200.422 1.00 17.87  ? 135 GLU D O     1 
ATOM   6461  C  CB    . GLU D 1 135 ? 216.302 179.493 197.944 1.00 21.78  ? 135 GLU D CB    1 
ATOM   6462  C  CG    . GLU D 1 135 ? 215.157 178.631 197.435 1.00 26.45  ? 135 GLU D CG    1 
ATOM   6463  C  CD    . GLU D 1 135 ? 215.018 177.323 198.182 1.00 31.37  ? 135 GLU D CD    1 
ATOM   6464  O  OE1   . GLU D 1 135 ? 213.972 177.114 198.841 1.00 35.50  ? 135 GLU D OE1   1 
ATOM   6465  O  OE2   . GLU D 1 135 ? 215.955 176.503 198.082 1.00 34.34  ? 135 GLU D OE2   1 
ATOM   6466  N  N     . MET D 1 136 ? 217.385 181.954 199.589 1.00 14.80  ? 136 MET D N     1 
ATOM   6467  C  CA    . MET D 1 136 ? 218.495 182.812 199.972 1.00 13.63  ? 136 MET D CA    1 
ATOM   6468  C  C     . MET D 1 136 ? 218.573 182.957 201.491 1.00 13.76  ? 136 MET D C     1 
ATOM   6469  O  O     . MET D 1 136 ? 219.655 183.177 202.034 1.00 14.01  ? 136 MET D O     1 
ATOM   6470  C  CB    . MET D 1 136 ? 218.388 184.196 199.326 1.00 12.92  ? 136 MET D CB    1 
ATOM   6471  C  CG    . MET D 1 136 ? 218.534 184.196 197.829 1.00 12.80  ? 136 MET D CG    1 
ATOM   6472  S  SD    . MET D 1 136 ? 217.948 185.743 197.112 1.00 12.50  ? 136 MET D SD    1 
ATOM   6473  C  CE    . MET D 1 136 ? 218.533 185.582 195.431 1.00 12.18  ? 136 MET D CE    1 
ATOM   6474  N  N     . GLY D 1 137 ? 217.434 182.872 202.179 1.00 14.58  ? 137 GLY D N     1 
ATOM   6475  C  CA    . GLY D 1 137 ? 217.412 182.966 203.629 1.00 16.12  ? 137 GLY D CA    1 
ATOM   6476  C  C     . GLY D 1 137 ? 218.255 181.888 204.304 1.00 17.75  ? 137 GLY D C     1 
ATOM   6477  O  O     . GLY D 1 137 ? 218.718 182.078 205.423 1.00 19.65  ? 137 GLY D O     1 
ATOM   6478  N  N     . GLN D 1 138 ? 218.432 180.743 203.639 1.00 20.18  ? 138 GLN D N     1 
ATOM   6479  C  CA    . GLN D 1 138 ? 219.235 179.663 204.193 1.00 23.72  ? 138 GLN D CA    1 
ATOM   6480  C  C     . GLN D 1 138 ? 220.734 179.938 204.080 1.00 22.75  ? 138 GLN D C     1 
ATOM   6481  O  O     . GLN D 1 138 ? 221.522 179.244 204.707 1.00 25.62  ? 138 GLN D O     1 
ATOM   6482  C  CB    . GLN D 1 138 ? 218.901 178.354 203.483 1.00 27.37  ? 138 GLN D CB    1 
ATOM   6483  C  CG    . GLN D 1 138 ? 217.492 177.853 203.779 1.00 32.09  ? 138 GLN D CG    1 
ATOM   6484  C  CD    . GLN D 1 138 ? 216.944 176.948 202.697 1.00 41.13  ? 138 GLN D CD    1 
ATOM   6485  O  OE1   . GLN D 1 138 ? 217.665 176.475 201.806 1.00 45.56  ? 138 GLN D OE1   1 
ATOM   6486  N  NE2   . GLN D 1 138 ? 215.643 176.708 202.759 1.00 44.59  ? 138 GLN D NE2   1 
ATOM   6487  N  N     . ASN D 1 139 ? 221.136 180.928 203.281 1.00 21.03  ? 139 ASN D N     1 
ATOM   6488  C  CA    . ASN D 1 139 ? 222.545 181.256 203.136 1.00 19.92  ? 139 ASN D CA    1 
ATOM   6489  C  C     . ASN D 1 139 ? 223.077 181.862 204.430 1.00 20.41  ? 139 ASN D C     1 
ATOM   6490  O  O     . ASN D 1 139 ? 222.397 182.637 205.089 1.00 20.02  ? 139 ASN D O     1 
ATOM   6491  C  CB    . ASN D 1 139 ? 222.783 182.213 201.970 1.00 18.90  ? 139 ASN D CB    1 
ATOM   6492  C  CG    . ASN D 1 139 ? 222.487 181.587 200.633 1.00 18.00  ? 139 ASN D CG    1 
ATOM   6493  O  OD1   . ASN D 1 139 ? 222.549 180.362 200.492 1.00 18.55  ? 139 ASN D OD1   1 
ATOM   6494  N  ND2   . ASN D 1 139 ? 222.168 182.404 199.636 1.00 17.15  ? 139 ASN D ND2   1 
ATOM   6495  N  N     . GLU D 1 140 ? 224.324 181.538 204.761 1.00 22.87  ? 140 GLU D N     1 
ATOM   6496  C  CA    . GLU D 1 140 ? 225.036 182.263 205.795 1.00 26.08  ? 140 GLU D CA    1 
ATOM   6497  C  C     . GLU D 1 140 ? 225.362 183.653 205.271 1.00 23.70  ? 140 GLU D C     1 
ATOM   6498  O  O     . GLU D 1 140 ? 225.845 183.796 204.152 1.00 24.60  ? 140 GLU D O     1 
ATOM   6499  C  CB    . GLU D 1 140 ? 226.319 181.535 206.193 1.00 31.31  ? 140 GLU D CB    1 
ATOM   6500  C  CG    . GLU D 1 140 ? 226.064 180.319 207.081 1.00 39.02  ? 140 GLU D CG    1 
ATOM   6501  C  CD    . GLU D 1 140 ? 225.350 180.677 208.375 1.00 47.37  ? 140 GLU D CD    1 
ATOM   6502  O  OE1   . GLU D 1 140 ? 224.400 179.954 208.753 1.00 50.65  ? 140 GLU D OE1   1 
ATOM   6503  O  OE2   . GLU D 1 140 ? 225.714 181.722 208.968 1.00 53.47  ? 140 GLU D OE2   1 
ATOM   6504  N  N     . PRO D 1 141 ? 225.119 184.724 206.050 1.00 22.93  ? 141 PRO D N     1 
ATOM   6505  C  CA    . PRO D 1 141 ? 225.468 186.069 205.594 1.00 23.58  ? 141 PRO D CA    1 
ATOM   6506  C  C     . PRO D 1 141 ? 226.960 186.184 205.306 1.00 24.49  ? 141 PRO D C     1 
ATOM   6507  O  O     . PRO D 1 141 ? 227.779 185.595 206.008 1.00 25.22  ? 141 PRO D O     1 
ATOM   6508  C  CB    . PRO D 1 141 ? 225.040 186.975 206.745 1.00 22.78  ? 141 PRO D CB    1 
ATOM   6509  C  CG    . PRO D 1 141 ? 224.063 186.141 207.544 1.00 23.58  ? 141 PRO D CG    1 
ATOM   6510  C  CD    . PRO D 1 141 ? 224.511 184.709 207.389 1.00 22.95  ? 141 PRO D CD    1 
ATOM   6511  N  N     . ASP D 1 142 ? 227.304 186.947 204.268 1.00 25.19  ? 142 ASP D N     1 
ATOM   6512  C  CA    . ASP D 1 142 ? 228.694 187.154 203.899 1.00 26.71  ? 142 ASP D CA    1 
ATOM   6513  C  C     . ASP D 1 142 ? 229.309 188.180 204.856 1.00 28.03  ? 142 ASP D C     1 
ATOM   6514  O  O     . ASP D 1 142 ? 228.714 188.530 205.870 1.00 26.42  ? 142 ASP D O     1 
ATOM   6515  C  CB    . ASP D 1 142 ? 228.805 187.557 202.439 1.00 26.51  ? 142 ASP D CB    1 
ATOM   6516  C  CG    . ASP D 1 142 ? 228.178 188.905 202.108 1.00 27.87  ? 142 ASP D CG    1 
ATOM   6517  O  OD1   . ASP D 1 142 ? 227.596 189.524 203.029 1.00 27.15  ? 142 ASP D OD1   1 
ATOM   6518  O  OD2   . ASP D 1 142 ? 228.252 189.303 200.923 1.00 29.19  ? 142 ASP D OD2   1 
ATOM   6519  N  N     . GLN D 1 143 ? 230.505 188.671 204.528 1.00 31.64  ? 143 GLN D N     1 
ATOM   6520  C  CA    . GLN D 1 143 ? 231.201 189.630 205.367 1.00 35.36  ? 143 GLN D CA    1 
ATOM   6521  C  C     . GLN D 1 143 ? 230.368 190.899 205.568 1.00 32.25  ? 143 GLN D C     1 
ATOM   6522  O  O     . GLN D 1 143 ? 230.430 191.524 206.629 1.00 33.12  ? 143 GLN D O     1 
ATOM   6523  C  CB    . GLN D 1 143 ? 232.571 189.996 204.794 1.00 42.84  ? 143 GLN D CB    1 
ATOM   6524  C  CG    . GLN D 1 143 ? 232.531 190.540 203.368 1.00 51.89  ? 143 GLN D CG    1 
ATOM   6525  C  CD    . GLN D 1 143 ? 232.495 189.450 202.312 1.00 61.24  ? 143 GLN D CD    1 
ATOM   6526  O  OE1   . GLN D 1 143 ? 232.458 188.251 202.619 1.00 63.95  ? 143 GLN D OE1   1 
ATOM   6527  N  NE2   . GLN D 1 143 ? 232.448 189.865 201.055 1.00 67.23  ? 143 GLN D NE2   1 
ATOM   6528  N  N     . GLY D 1 144 ? 229.579 191.270 204.554 1.00 28.58  ? 144 GLY D N     1 
ATOM   6529  C  CA    . GLY D 1 144 ? 228.736 192.451 204.636 1.00 24.99  ? 144 GLY D CA    1 
ATOM   6530  C  C     . GLY D 1 144 ? 227.336 192.157 205.172 1.00 23.12  ? 144 GLY D C     1 
ATOM   6531  O  O     . GLY D 1 144 ? 226.488 193.046 205.207 1.00 23.61  ? 144 GLY D O     1 
ATOM   6532  N  N     . GLY D 1 145 ? 227.072 190.912 205.579 1.00 19.96  ? 145 GLY D N     1 
ATOM   6533  C  CA    . GLY D 1 145 ? 225.762 190.555 206.097 1.00 17.98  ? 145 GLY D CA    1 
ATOM   6534  C  C     . GLY D 1 145 ? 224.754 190.209 205.001 1.00 16.63  ? 145 GLY D C     1 
ATOM   6535  O  O     . GLY D 1 145 ? 223.578 190.036 205.303 1.00 17.35  ? 145 GLY D O     1 
ATOM   6536  N  N     . GLN D 1 146 ? 225.199 190.105 203.748 1.00 14.59  ? 146 GLN D N     1 
ATOM   6537  C  CA    . GLN D 1 146 ? 224.304 189.906 202.620 1.00 13.86  ? 146 GLN D CA    1 
ATOM   6538  C  C     . GLN D 1 146 ? 224.062 188.417 202.375 1.00 13.00  ? 146 GLN D C     1 
ATOM   6539  O  O     . GLN D 1 146 ? 224.999 187.629 202.354 1.00 13.28  ? 146 GLN D O     1 
ATOM   6540  C  CB    . GLN D 1 146 ? 224.891 190.559 201.377 1.00 13.67  ? 146 GLN D CB    1 
ATOM   6541  C  CG    . GLN D 1 146 ? 224.028 190.422 200.132 1.00 13.89  ? 146 GLN D CG    1 
ATOM   6542  C  CD    . GLN D 1 146 ? 224.640 191.110 198.934 1.00 14.61  ? 146 GLN D CD    1 
ATOM   6543  O  OE1   . GLN D 1 146 ? 224.683 192.338 198.847 1.00 15.32  ? 146 GLN D OE1   1 
ATOM   6544  N  NE2   . GLN D 1 146 ? 225.158 190.312 198.020 1.00 15.59  ? 146 GLN D NE2   1 
ATOM   6545  N  N     . ARG D 1 147 ? 222.789 188.055 202.188 1.00 12.06  ? 147 ARG D N     1 
ATOM   6546  C  CA    . ARG D 1 147 ? 222.412 186.691 201.865 1.00 11.97  ? 147 ARG D CA    1 
ATOM   6547  C  C     . ARG D 1 147 ? 222.065 186.514 200.391 1.00 11.05  ? 147 ARG D C     1 
ATOM   6548  O  O     . ARG D 1 147 ? 222.123 185.402 199.886 1.00 12.72  ? 147 ARG D O     1 
ATOM   6549  C  CB    . ARG D 1 147 ? 221.217 186.249 202.705 1.00 12.69  ? 147 ARG D CB    1 
ATOM   6550  C  CG    . ARG D 1 147 ? 221.578 185.822 204.116 1.00 13.81  ? 147 ARG D CG    1 
ATOM   6551  C  CD    . ARG D 1 147 ? 220.372 185.240 204.807 1.00 14.86  ? 147 ARG D CD    1 
ATOM   6552  N  NE    . ARG D 1 147 ? 220.685 184.765 206.161 1.00 16.41  ? 147 ARG D NE    1 
ATOM   6553  C  CZ    . ARG D 1 147 ? 220.601 185.500 207.254 1.00 18.50  ? 147 ARG D CZ    1 
ATOM   6554  N  NH1   . ARG D 1 147 ? 220.270 186.780 207.192 1.00 19.18  ? 147 ARG D NH1   1 
ATOM   6555  N  NH2   . ARG D 1 147 ? 220.870 184.942 208.422 1.00 20.37  ? 147 ARG D NH2   1 
ATOM   6556  N  N     . GLY D 1 148 ? 221.686 187.582 199.691 1.00 10.27  ? 148 GLY D N     1 
ATOM   6557  C  CA    . GLY D 1 148 ? 221.417 187.456 198.281 1.00 9.47   ? 148 GLY D CA    1 
ATOM   6558  C  C     . GLY D 1 148 ? 221.033 188.782 197.648 1.00 9.16   ? 148 GLY D C     1 
ATOM   6559  O  O     . GLY D 1 148 ? 220.905 189.794 198.329 1.00 8.65   ? 148 GLY D O     1 
ATOM   6560  N  N     . VAL D 1 149 ? 220.880 188.737 196.328 1.00 8.98   ? 149 VAL D N     1 
ATOM   6561  C  CA    . VAL D 1 149 ? 220.481 189.897 195.549 1.00 9.07   ? 149 VAL D CA    1 
ATOM   6562  C  C     . VAL D 1 149 ? 219.375 189.452 194.606 1.00 8.45   ? 149 VAL D C     1 
ATOM   6563  O  O     . VAL D 1 149 ? 219.517 188.445 193.914 1.00 8.51   ? 149 VAL D O     1 
ATOM   6564  C  CB    . VAL D 1 149 ? 221.647 190.511 194.746 1.00 9.68   ? 149 VAL D CB    1 
ATOM   6565  C  CG1   . VAL D 1 149 ? 221.226 191.825 194.091 1.00 9.76   ? 149 VAL D CG1   1 
ATOM   6566  C  CG2   . VAL D 1 149 ? 222.882 190.712 195.600 1.00 10.57  ? 149 VAL D CG2   1 
ATOM   6567  N  N     . ILE D 1 150 ? 218.281 190.219 194.585 1.00 8.12   ? 150 ILE D N     1 
ATOM   6568  C  CA    . ILE D 1 150 ? 217.200 189.994 193.644 1.00 8.11   ? 150 ILE D CA    1 
ATOM   6569  C  C     . ILE D 1 150 ? 217.108 191.187 192.708 1.00 7.88   ? 150 ILE D C     1 
ATOM   6570  O  O     . ILE D 1 150 ? 216.997 192.326 193.162 1.00 8.34   ? 150 ILE D O     1 
ATOM   6571  C  CB    . ILE D 1 150 ? 215.876 189.750 194.382 1.00 8.08   ? 150 ILE D CB    1 
ATOM   6572  C  CG1   . ILE D 1 150 ? 215.957 188.510 195.255 1.00 8.10   ? 150 ILE D CG1   1 
ATOM   6573  C  CG2   . ILE D 1 150 ? 214.711 189.666 193.394 1.00 7.78   ? 150 ILE D CG2   1 
ATOM   6574  C  CD1   . ILE D 1 150 ? 214.791 188.340 196.207 1.00 8.56   ? 150 ILE D CD1   1 
ATOM   6575  N  N     . ILE D 1 151 ? 217.152 190.904 191.409 1.00 7.97   ? 151 ILE D N     1 
ATOM   6576  C  CA    . ILE D 1 151 ? 217.060 191.921 190.380 1.00 8.77   ? 151 ILE D CA    1 
ATOM   6577  C  C     . ILE D 1 151 ? 215.837 191.630 189.522 1.00 9.00   ? 151 ILE D C     1 
ATOM   6578  O  O     . ILE D 1 151 ? 215.707 190.538 188.977 1.00 9.52   ? 151 ILE D O     1 
ATOM   6579  C  CB    . ILE D 1 151 ? 218.346 191.980 189.540 1.00 9.13   ? 151 ILE D CB    1 
ATOM   6580  C  CG1   . ILE D 1 151 ? 219.529 192.400 190.401 1.00 9.62   ? 151 ILE D CG1   1 
ATOM   6581  C  CG2   . ILE D 1 151 ? 218.178 192.925 188.359 1.00 9.25   ? 151 ILE D CG2   1 
ATOM   6582  C  CD1   . ILE D 1 151 ? 220.832 191.761 190.016 1.00 9.94   ? 151 ILE D CD1   1 
ATOM   6583  N  N     . ASN D 1 152 ? 214.959 192.627 189.408 1.00 9.00   ? 152 ASN D N     1 
ATOM   6584  C  CA    . ASN D 1 152 ? 213.742 192.506 188.624 1.00 9.35   ? 152 ASN D CA    1 
ATOM   6585  C  C     . ASN D 1 152 ? 213.868 193.342 187.362 1.00 10.05  ? 152 ASN D C     1 
ATOM   6586  O  O     . ASN D 1 152 ? 214.636 194.299 187.307 1.00 9.57   ? 152 ASN D O     1 
ATOM   6587  C  CB    . ASN D 1 152 ? 212.512 192.947 189.416 1.00 9.89   ? 152 ASN D CB    1 
ATOM   6588  C  CG    . ASN D 1 152 ? 212.518 192.374 190.807 1.00 10.64  ? 152 ASN D CG    1 
ATOM   6589  O  OD1   . ASN D 1 152 ? 212.542 191.149 190.971 1.00 10.89  ? 152 ASN D OD1   1 
ATOM   6590  N  ND2   . ASN D 1 152 ? 212.532 193.228 191.822 1.00 11.56  ? 152 ASN D ND2   1 
ATOM   6591  N  N     . THR D 1 153 ? 213.085 192.977 186.351 1.00 10.74  ? 153 THR D N     1 
ATOM   6592  C  CA    . THR D 1 153 ? 213.050 193.706 185.101 1.00 12.02  ? 153 THR D CA    1 
ATOM   6593  C  C     . THR D 1 153 ? 211.680 194.365 184.956 1.00 12.75  ? 153 THR D C     1 
ATOM   6594  O  O     . THR D 1 153 ? 210.688 193.705 184.648 1.00 13.79  ? 153 THR D O     1 
ATOM   6595  C  CB    . THR D 1 153 ? 213.345 192.782 183.924 1.00 12.77  ? 153 THR D CB    1 
ATOM   6596  O  OG1   . THR D 1 153 ? 214.545 192.053 184.178 1.00 14.45  ? 153 THR D OG1   1 
ATOM   6597  C  CG2   . THR D 1 153 ? 213.499 193.568 182.638 1.00 13.18  ? 153 THR D CG2   1 
ATOM   6598  N  N     . ALA D 1 154 ? 211.651 195.682 185.165 1.00 13.69  ? 154 ALA D N     1 
ATOM   6599  C  CA    . ALA D 1 154 ? 210.507 196.508 184.812 1.00 14.50  ? 154 ALA D CA    1 
ATOM   6600  C  C     . ALA D 1 154 ? 210.693 196.969 183.369 1.00 17.04  ? 154 ALA D C     1 
ATOM   6601  O  O     . ALA D 1 154 ? 211.388 196.324 182.597 1.00 20.02  ? 154 ALA D O     1 
ATOM   6602  C  CB    . ALA D 1 154 ? 210.370 197.680 185.769 1.00 15.02  ? 154 ALA D CB    1 
ATOM   6603  N  N     . SER D 1 155 ? 210.059 198.074 182.996 1.00 19.15  ? 155 SER D N     1 
ATOM   6604  C  CA    . SER D 1 155 ? 210.279 198.695 181.703 1.00 19.46  ? 155 SER D CA    1 
ATOM   6605  C  C     . SER D 1 155 ? 210.140 200.200 181.861 1.00 18.62  ? 155 SER D C     1 
ATOM   6606  O  O     . SER D 1 155 ? 209.556 200.693 182.829 1.00 19.21  ? 155 SER D O     1 
ATOM   6607  C  CB    . SER D 1 155 ? 209.306 198.157 180.648 1.00 20.78  ? 155 SER D CB    1 
ATOM   6608  O  OG    . SER D 1 155 ? 209.449 198.838 179.412 1.00 22.50  ? 155 SER D OG    1 
ATOM   6609  N  N     . VAL D 1 156 ? 210.653 200.934 180.878 1.00 18.95  ? 156 VAL D N     1 
ATOM   6610  C  CA    . VAL D 1 156 ? 210.357 202.355 180.783 1.00 19.56  ? 156 VAL D CA    1 
ATOM   6611  C  C     . VAL D 1 156 ? 208.855 202.562 180.591 1.00 17.72  ? 156 VAL D C     1 
ATOM   6612  O  O     . VAL D 1 156 ? 208.354 203.647 180.845 1.00 18.42  ? 156 VAL D O     1 
ATOM   6613  C  CB    . VAL D 1 156 ? 211.158 203.012 179.644 1.00 22.33  ? 156 VAL D CB    1 
ATOM   6614  C  CG1   . VAL D 1 156 ? 212.644 203.014 179.974 1.00 24.12  ? 156 VAL D CG1   1 
ATOM   6615  C  CG2   . VAL D 1 156 ? 210.882 202.351 178.305 1.00 22.73  ? 156 VAL D CG2   1 
ATOM   6616  N  N     . ALA D 1 157 ? 208.134 201.535 180.129 1.00 17.56  ? 157 ALA D N     1 
ATOM   6617  C  CA    . ALA D 1 157 ? 206.682 201.599 180.030 1.00 18.85  ? 157 ALA D CA    1 
ATOM   6618  C  C     . ALA D 1 157 ? 206.020 201.826 181.390 1.00 19.12  ? 157 ALA D C     1 
ATOM   6619  O  O     . ALA D 1 157 ? 204.895 202.312 181.441 1.00 18.26  ? 157 ALA D O     1 
ATOM   6620  C  CB    . ALA D 1 157 ? 206.139 200.353 179.385 1.00 17.79  ? 157 ALA D CB    1 
ATOM   6621  N  N     . ALA D 1 158 ? 206.724 201.514 182.486 1.00 20.20  ? 158 ALA D N     1 
ATOM   6622  C  CA    . ALA D 1 158 ? 206.199 201.811 183.816 1.00 21.29  ? 158 ALA D CA    1 
ATOM   6623  C  C     . ALA D 1 158 ? 206.088 203.313 184.052 1.00 19.69  ? 158 ALA D C     1 
ATOM   6624  O  O     . ALA D 1 158 ? 205.343 203.741 184.924 1.00 20.52  ? 158 ALA D O     1 
ATOM   6625  C  CB    . ALA D 1 158 ? 207.058 201.144 184.876 1.00 21.77  ? 158 ALA D CB    1 
ATOM   6626  N  N     . PHE D 1 159 ? 206.847 204.115 183.290 1.00 21.44  ? 159 PHE D N     1 
ATOM   6627  C  CA    . PHE D 1 159 ? 206.885 205.561 183.475 1.00 23.95  ? 159 PHE D CA    1 
ATOM   6628  C  C     . PHE D 1 159 ? 206.273 206.304 182.287 1.00 24.78  ? 159 PHE D C     1 
ATOM   6629  O  O     . PHE D 1 159 ? 205.553 207.281 182.467 1.00 24.61  ? 159 PHE D O     1 
ATOM   6630  C  CB    . PHE D 1 159 ? 208.326 206.021 183.689 1.00 25.71  ? 159 PHE D CB    1 
ATOM   6631  C  CG    . PHE D 1 159 ? 209.006 205.296 184.834 1.00 27.21  ? 159 PHE D CG    1 
ATOM   6632  C  CD1   . PHE D 1 159 ? 208.611 205.528 186.150 1.00 28.45  ? 159 PHE D CD1   1 
ATOM   6633  C  CD2   . PHE D 1 159 ? 210.021 204.383 184.586 1.00 27.70  ? 159 PHE D CD2   1 
ATOM   6634  C  CE1   . PHE D 1 159 ? 209.217 204.843 187.193 1.00 28.92  ? 159 PHE D CE1   1 
ATOM   6635  C  CE2   . PHE D 1 159 ? 210.629 203.709 185.633 1.00 28.35  ? 159 PHE D CE2   1 
ATOM   6636  C  CZ    . PHE D 1 159 ? 210.232 203.951 186.935 1.00 28.17  ? 159 PHE D CZ    1 
ATOM   6637  N  N     . GLU D 1 160 ? 206.597 205.872 181.062 1.00 25.22  ? 160 GLU D N     1 
ATOM   6638  C  CA    . GLU D 1 160 ? 206.005 206.444 179.863 1.00 27.07  ? 160 GLU D CA    1 
ATOM   6639  C  C     . GLU D 1 160 ? 205.457 205.307 178.994 1.00 25.26  ? 160 GLU D C     1 
ATOM   6640  O  O     . GLU D 1 160 ? 206.103 204.865 178.045 1.00 27.68  ? 160 GLU D O     1 
ATOM   6641  C  CB    . GLU D 1 160 ? 207.004 207.297 179.081 1.00 30.81  ? 160 GLU D CB    1 
ATOM   6642  C  CG    . GLU D 1 160 ? 207.636 208.444 179.866 1.00 35.58  ? 160 GLU D CG    1 
ATOM   6643  C  CD    . GLU D 1 160 ? 208.974 208.068 180.472 1.00 38.27  ? 160 GLU D CD    1 
ATOM   6644  O  OE1   . GLU D 1 160 ? 209.305 208.658 181.533 1.00 41.26  ? 160 GLU D OE1   1 
ATOM   6645  O  OE2   . GLU D 1 160 ? 209.714 207.256 179.879 1.00 38.50  ? 160 GLU D OE2   1 
ATOM   6646  N  N     . GLY D 1 161 ? 204.292 204.783 179.360 1.00 21.93  ? 161 GLY D N     1 
ATOM   6647  C  CA    . GLY D 1 161 ? 203.682 203.726 178.585 1.00 21.30  ? 161 GLY D CA    1 
ATOM   6648  C  C     . GLY D 1 161 ? 203.035 204.288 177.323 1.00 21.56  ? 161 GLY D C     1 
ATOM   6649  O  O     . GLY D 1 161 ? 202.385 205.330 177.359 1.00 19.19  ? 161 GLY D O     1 
ATOM   6650  N  N     . GLN D 1 162 ? 203.225 203.566 176.217 1.00 21.83  ? 162 GLN D N     1 
ATOM   6651  C  CA    . GLN D 1 162 ? 202.739 204.022 174.933 1.00 23.00  ? 162 GLN D CA    1 
ATOM   6652  C  C     . GLN D 1 162 ? 201.283 203.615 174.754 1.00 21.17  ? 162 GLN D C     1 
ATOM   6653  O  O     . GLN D 1 162 ? 200.729 202.860 175.544 1.00 19.23  ? 162 GLN D O     1 
ATOM   6654  C  CB    . GLN D 1 162 ? 203.608 203.438 173.826 1.00 24.70  ? 162 GLN D CB    1 
ATOM   6655  C  CG    . GLN D 1 162 ? 204.968 204.108 173.704 1.00 28.15  ? 162 GLN D CG    1 
ATOM   6656  C  CD    . GLN D 1 162 ? 205.658 203.721 172.416 1.00 31.09  ? 162 GLN D CD    1 
ATOM   6657  O  OE1   . GLN D 1 162 ? 205.936 202.540 172.166 1.00 32.63  ? 162 GLN D OE1   1 
ATOM   6658  N  NE2   . GLN D 1 162 ? 205.922 204.712 171.572 1.00 33.86  ? 162 GLN D NE2   1 
ATOM   6659  N  N     . VAL D 1 163 ? 200.674 204.126 173.685 1.00 20.58  ? 163 VAL D N     1 
ATOM   6660  C  CA    . VAL D 1 163 ? 199.344 203.689 173.295 1.00 19.20  ? 163 VAL D CA    1 
ATOM   6661  C  C     . VAL D 1 163 ? 199.367 202.185 173.038 1.00 17.46  ? 163 VAL D C     1 
ATOM   6662  O  O     . VAL D 1 163 ? 200.226 201.672 172.331 1.00 18.63  ? 163 VAL D O     1 
ATOM   6663  C  CB    . VAL D 1 163 ? 198.875 204.466 172.056 1.00 19.36  ? 163 VAL D CB    1 
ATOM   6664  C  CG1   . VAL D 1 163 ? 197.631 203.833 171.447 1.00 19.35  ? 163 VAL D CG1   1 
ATOM   6665  C  CG2   . VAL D 1 163 ? 198.669 205.942 172.375 1.00 19.29  ? 163 VAL D CG2   1 
ATOM   6666  N  N     . GLY D 1 164 ? 198.411 201.475 173.624 1.00 17.03  ? 164 GLY D N     1 
ATOM   6667  C  CA    . GLY D 1 164 ? 198.323 200.032 173.478 1.00 16.93  ? 164 GLY D CA    1 
ATOM   6668  C  C     . GLY D 1 164 ? 199.135 199.264 174.530 1.00 17.29  ? 164 GLY D C     1 
ATOM   6669  O  O     . GLY D 1 164 ? 199.140 198.034 174.518 1.00 16.55  ? 164 GLY D O     1 
ATOM   6670  N  N     . GLN D 1 165 ? 199.797 199.963 175.460 1.00 17.26  ? 165 GLN D N     1 
ATOM   6671  C  CA    . GLN D 1 165 ? 200.656 199.302 176.436 1.00 17.97  ? 165 GLN D CA    1 
ATOM   6672  C  C     . GLN D 1 165 ? 200.071 199.372 177.849 1.00 16.71  ? 165 GLN D C     1 
ATOM   6673  O  O     . GLN D 1 165 ? 200.814 199.268 178.823 1.00 18.46  ? 165 GLN D O     1 
ATOM   6674  C  CB    . GLN D 1 165 ? 202.030 199.978 176.463 1.00 19.25  ? 165 GLN D CB    1 
ATOM   6675  C  CG    . GLN D 1 165 ? 203.018 199.450 175.431 1.00 21.24  ? 165 GLN D CG    1 
ATOM   6676  C  CD    . GLN D 1 165 ? 204.441 199.843 175.762 1.00 22.24  ? 165 GLN D CD    1 
ATOM   6677  O  OE1   . GLN D 1 165 ? 204.712 200.982 176.145 1.00 20.53  ? 165 GLN D OE1   1 
ATOM   6678  N  NE2   . GLN D 1 165 ? 205.357 198.887 175.660 1.00 24.30  ? 165 GLN D NE2   1 
ATOM   6679  N  N     . ALA D 1 166 ? 198.747 199.515 177.976 1.00 15.00  ? 166 ALA D N     1 
ATOM   6680  C  CA    . ALA D 1 166 ? 198.120 199.598 179.287 1.00 14.54  ? 166 ALA D CA    1 
ATOM   6681  C  C     . ALA D 1 166 ? 198.447 198.368 180.142 1.00 14.15  ? 166 ALA D C     1 
ATOM   6682  O  O     . ALA D 1 166 ? 198.807 198.500 181.311 1.00 13.45  ? 166 ALA D O     1 
ATOM   6683  C  CB    . ALA D 1 166 ? 196.627 199.783 179.148 1.00 15.02  ? 166 ALA D CB    1 
ATOM   6684  N  N     . ALA D 1 167 ? 198.280 197.169 179.587 1.00 13.18  ? 167 ALA D N     1 
ATOM   6685  C  CA    . ALA D 1 167 ? 198.531 195.943 180.324 1.00 13.62  ? 167 ALA D CA    1 
ATOM   6686  C  C     . ALA D 1 167 ? 200.002 195.850 180.713 1.00 13.78  ? 167 ALA D C     1 
ATOM   6687  O  O     . ALA D 1 167 ? 200.333 195.503 181.837 1.00 13.76  ? 167 ALA D O     1 
ATOM   6688  C  CB    . ALA D 1 167 ? 198.106 194.734 179.509 1.00 13.02  ? 167 ALA D CB    1 
ATOM   6689  N  N     . TYR D 1 168 ? 200.891 196.143 179.769 1.00 13.70  ? 168 TYR D N     1 
ATOM   6690  C  CA    . TYR D 1 168 ? 202.310 196.045 180.014 1.00 14.56  ? 168 TYR D CA    1 
ATOM   6691  C  C     . TYR D 1 168 ? 202.739 197.079 181.053 1.00 13.28  ? 168 TYR D C     1 
ATOM   6692  O  O     . TYR D 1 168 ? 203.526 196.778 181.939 1.00 13.75  ? 168 TYR D O     1 
ATOM   6693  C  CB    . TYR D 1 168 ? 203.049 196.208 178.685 1.00 16.23  ? 168 TYR D CB    1 
ATOM   6694  C  CG    . TYR D 1 168 ? 204.519 195.851 178.759 1.00 17.59  ? 168 TYR D CG    1 
ATOM   6695  C  CD1   . TYR D 1 168 ? 204.910 194.537 178.935 1.00 17.88  ? 168 TYR D CD1   1 
ATOM   6696  C  CD2   . TYR D 1 168 ? 205.508 196.820 178.639 1.00 19.42  ? 168 TYR D CD2   1 
ATOM   6697  C  CE1   . TYR D 1 168 ? 206.249 194.188 178.973 1.00 19.46  ? 168 TYR D CE1   1 
ATOM   6698  C  CE2   . TYR D 1 168 ? 206.854 196.488 178.696 1.00 19.81  ? 168 TYR D CE2   1 
ATOM   6699  C  CZ    . TYR D 1 168 ? 207.222 195.169 178.865 1.00 20.15  ? 168 TYR D CZ    1 
ATOM   6700  O  OH    . TYR D 1 168 ? 208.542 194.828 178.924 1.00 22.32  ? 168 TYR D OH    1 
ATOM   6701  N  N     . SER D 1 169 ? 202.251 198.309 180.925 1.00 12.27  ? 169 SER D N     1 
ATOM   6702  C  CA    . SER D 1 169 ? 202.612 199.381 181.842 1.00 11.75  ? 169 SER D CA    1 
ATOM   6703  C  C     . SER D 1 169 ? 202.126 199.100 183.265 1.00 10.44  ? 169 SER D C     1 
ATOM   6704  O  O     . SER D 1 169 ? 202.828 199.408 184.226 1.00 10.18  ? 169 SER D O     1 
ATOM   6705  C  CB    . SER D 1 169 ? 202.101 200.711 181.351 1.00 11.87  ? 169 SER D CB    1 
ATOM   6706  O  OG    . SER D 1 169 ? 202.729 201.059 180.127 1.00 11.80  ? 169 SER D OG    1 
ATOM   6707  N  N     . ALA D 1 170 ? 200.922 198.527 183.393 1.00 9.69   ? 170 ALA D N     1 
ATOM   6708  C  CA    . ALA D 1 170 ? 200.397 198.164 184.698 1.00 9.56   ? 170 ALA D CA    1 
ATOM   6709  C  C     . ALA D 1 170 ? 201.316 197.143 185.375 1.00 9.80   ? 170 ALA D C     1 
ATOM   6710  O  O     . ALA D 1 170 ? 201.655 197.295 186.546 1.00 9.01   ? 170 ALA D O     1 
ATOM   6711  C  CB    . ALA D 1 170 ? 198.996 197.634 184.587 1.00 9.47   ? 170 ALA D CB    1 
ATOM   6712  N  N     . SER D 1 171 ? 201.701 196.096 184.631 1.00 9.83   ? 171 SER D N     1 
ATOM   6713  C  CA    . SER D 1 171 ? 202.537 195.044 185.182 1.00 11.09  ? 171 SER D CA    1 
ATOM   6714  C  C     . SER D 1 171 ? 203.892 195.615 185.600 1.00 11.60  ? 171 SER D C     1 
ATOM   6715  O  O     . SER D 1 171 ? 204.395 195.290 186.667 1.00 12.93  ? 171 SER D O     1 
ATOM   6716  C  CB    . SER D 1 171 ? 202.685 193.893 184.210 1.00 11.04  ? 171 SER D CB    1 
ATOM   6717  O  OG    . SER D 1 171 ? 203.582 194.222 183.157 1.00 10.81  ? 171 SER D OG    1 
ATOM   6718  N  N     . LYS D 1 172 ? 204.491 196.455 184.748 1.00 11.32  ? 172 LYS D N     1 
ATOM   6719  C  CA    . LYS D 1 172 ? 205.799 196.994 185.050 1.00 12.43  ? 172 LYS D CA    1 
ATOM   6720  C  C     . LYS D 1 172 ? 205.724 198.064 186.133 1.00 10.68  ? 172 LYS D C     1 
ATOM   6721  O  O     . LYS D 1 172 ? 206.630 198.176 186.946 1.00 11.18  ? 172 LYS D O     1 
ATOM   6722  C  CB    . LYS D 1 172 ? 206.466 197.514 183.776 1.00 13.97  ? 172 LYS D CB    1 
ATOM   6723  C  CG    . LYS D 1 172 ? 206.732 196.430 182.721 1.00 15.03  ? 172 LYS D CG    1 
ATOM   6724  C  CD    . LYS D 1 172 ? 207.238 195.117 183.296 1.00 15.95  ? 172 LYS D CD    1 
ATOM   6725  C  CE    . LYS D 1 172 ? 207.803 194.200 182.246 1.00 17.90  ? 172 LYS D CE    1 
ATOM   6726  N  NZ    . LYS D 1 172 ? 208.721 193.200 182.806 1.00 18.45  ? 172 LYS D NZ    1 
ATOM   6727  N  N     . GLY D 1 173 ? 204.649 198.850 186.149 1.00 10.09  ? 173 GLY D N     1 
ATOM   6728  C  CA    . GLY D 1 173 ? 204.407 199.787 187.243 1.00 8.72   ? 173 GLY D CA    1 
ATOM   6729  C  C     . GLY D 1 173 ? 204.251 199.056 188.578 1.00 7.99   ? 173 GLY D C     1 
ATOM   6730  O  O     . GLY D 1 173 ? 204.634 199.565 189.626 1.00 7.65   ? 173 GLY D O     1 
ATOM   6731  N  N     . GLY D 1 174 ? 203.659 197.857 188.548 1.00 7.58   ? 174 GLY D N     1 
ATOM   6732  C  CA    . GLY D 1 174 ? 203.541 197.042 189.743 1.00 7.52   ? 174 GLY D CA    1 
ATOM   6733  C  C     . GLY D 1 174 ? 204.912 196.590 190.260 1.00 7.53   ? 174 GLY D C     1 
ATOM   6734  O  O     . GLY D 1 174 ? 205.162 196.576 191.456 1.00 7.47   ? 174 GLY D O     1 
ATOM   6735  N  N     . ILE D 1 175 ? 205.801 196.201 189.353 1.00 7.88   ? 175 ILE D N     1 
ATOM   6736  C  CA    . ILE D 1 175 ? 207.146 195.788 189.748 1.00 8.14   ? 175 ILE D CA    1 
ATOM   6737  C  C     . ILE D 1 175 ? 207.891 196.964 190.382 1.00 8.15   ? 175 ILE D C     1 
ATOM   6738  O  O     . ILE D 1 175 ? 208.560 196.807 191.393 1.00 8.32   ? 175 ILE D O     1 
ATOM   6739  C  CB    . ILE D 1 175 ? 207.907 195.214 188.546 1.00 8.69   ? 175 ILE D CB    1 
ATOM   6740  C  CG1   . ILE D 1 175 ? 207.287 193.898 188.100 1.00 8.93   ? 175 ILE D CG1   1 
ATOM   6741  C  CG2   . ILE D 1 175 ? 209.392 195.035 188.875 1.00 8.63   ? 175 ILE D CG2   1 
ATOM   6742  C  CD1   . ILE D 1 175 ? 207.625 193.508 186.687 1.00 9.62   ? 175 ILE D CD1   1 
ATOM   6743  N  N     . VAL D 1 176 ? 207.779 198.147 189.790 1.00 8.50   ? 176 VAL D N     1 
ATOM   6744  C  CA    . VAL D 1 176 ? 208.388 199.338 190.357 1.00 9.53   ? 176 VAL D CA    1 
ATOM   6745  C  C     . VAL D 1 176 ? 207.790 199.615 191.736 1.00 9.80   ? 176 VAL D C     1 
ATOM   6746  O  O     . VAL D 1 176 ? 208.513 199.920 192.681 1.00 10.44  ? 176 VAL D O     1 
ATOM   6747  C  CB    . VAL D 1 176 ? 208.232 200.533 189.405 1.00 9.96   ? 176 VAL D CB    1 
ATOM   6748  C  CG1   . VAL D 1 176 ? 208.563 201.856 190.091 1.00 10.65  ? 176 VAL D CG1   1 
ATOM   6749  C  CG2   . VAL D 1 176 ? 209.061 200.321 188.143 1.00 10.03  ? 176 VAL D CG2   1 
ATOM   6750  N  N     . GLY D 1 177 ? 206.465 199.514 191.853 1.00 9.26   ? 177 GLY D N     1 
ATOM   6751  C  CA    . GLY D 1 177 ? 205.794 199.833 193.102 1.00 8.68   ? 177 GLY D CA    1 
ATOM   6752  C  C     . GLY D 1 177 ? 206.226 198.923 194.249 1.00 8.46   ? 177 GLY D C     1 
ATOM   6753  O  O     . GLY D 1 177 ? 206.385 199.378 195.367 1.00 7.95   ? 177 GLY D O     1 
ATOM   6754  N  N     . MET D 1 178 ? 206.406 197.631 193.982 1.00 8.35   ? 178 MET D N     1 
ATOM   6755  C  CA    . MET D 1 178 ? 206.703 196.690 195.050 1.00 9.12   ? 178 MET D CA    1 
ATOM   6756  C  C     . MET D 1 178 ? 208.205 196.538 195.303 1.00 8.45   ? 178 MET D C     1 
ATOM   6757  O  O     . MET D 1 178 ? 208.576 195.833 196.230 1.00 9.03   ? 178 MET D O     1 
ATOM   6758  C  CB    . MET D 1 178 ? 206.100 195.311 194.753 1.00 10.00  ? 178 MET D CB    1 
ATOM   6759  C  CG    . MET D 1 178 ? 206.719 194.610 193.571 1.00 11.63  ? 178 MET D CG    1 
ATOM   6760  S  SD    . MET D 1 178 ? 205.912 193.017 193.291 1.00 13.38  ? 178 MET D SD    1 
ATOM   6761  C  CE    . MET D 1 178 ? 207.031 192.343 192.058 1.00 13.29  ? 178 MET D CE    1 
ATOM   6762  N  N     . THR D 1 179 ? 209.058 197.208 194.528 1.00 7.74   ? 179 THR D N     1 
ATOM   6763  C  CA    . THR D 1 179 ? 210.501 197.096 194.713 1.00 7.72   ? 179 THR D CA    1 
ATOM   6764  C  C     . THR D 1 179 ? 210.907 197.566 196.112 1.00 7.48   ? 179 THR D C     1 
ATOM   6765  O  O     . THR D 1 179 ? 211.601 196.840 196.821 1.00 7.29   ? 179 THR D O     1 
ATOM   6766  C  CB    . THR D 1 179 ? 211.238 197.890 193.637 1.00 7.94   ? 179 THR D CB    1 
ATOM   6767  O  OG1   . THR D 1 179 ? 210.965 197.317 192.356 1.00 7.68   ? 179 THR D OG1   1 
ATOM   6768  C  CG2   . THR D 1 179 ? 212.734 197.912 193.892 1.00 8.24   ? 179 THR D CG2   1 
ATOM   6769  N  N     . LEU D 1 180 ? 210.476 198.767 196.511 1.00 7.34   ? 180 LEU D N     1 
ATOM   6770  C  CA    . LEU D 1 180 ? 210.847 199.297 197.813 1.00 7.65   ? 180 LEU D CA    1 
ATOM   6771  C  C     . LEU D 1 180 ? 210.272 198.468 198.966 1.00 7.41   ? 180 LEU D C     1 
ATOM   6772  O  O     . LEU D 1 180 ? 211.001 198.131 199.903 1.00 7.69   ? 180 LEU D O     1 
ATOM   6773  C  CB    . LEU D 1 180 ? 210.478 200.775 197.945 1.00 8.03   ? 180 LEU D CB    1 
ATOM   6774  C  CG    . LEU D 1 180 ? 210.849 201.403 199.294 1.00 8.44   ? 180 LEU D CG    1 
ATOM   6775  C  CD1   . LEU D 1 180 ? 212.349 201.299 199.585 1.00 8.63   ? 180 LEU D CD1   1 
ATOM   6776  C  CD2   . LEU D 1 180 ? 210.410 202.856 199.362 1.00 8.83   ? 180 LEU D CD2   1 
ATOM   6777  N  N     . PRO D 1 181 ? 208.957 198.148 199.004 1.00 7.70   ? 181 PRO D N     1 
ATOM   6778  C  CA    . PRO D 1 181 ? 208.439 197.348 200.115 1.00 7.63   ? 181 PRO D CA    1 
ATOM   6779  C  C     . PRO D 1 181 ? 209.122 195.987 200.270 1.00 7.19   ? 181 PRO D C     1 
ATOM   6780  O  O     . PRO D 1 181 ? 209.369 195.536 201.382 1.00 7.44   ? 181 PRO D O     1 
ATOM   6781  C  CB    . PRO D 1 181 ? 206.943 197.183 199.857 1.00 7.92   ? 181 PRO D CB    1 
ATOM   6782  C  CG    . PRO D 1 181 ? 206.644 197.993 198.630 1.00 8.06   ? 181 PRO D CG    1 
ATOM   6783  C  CD    . PRO D 1 181 ? 207.911 198.581 198.061 1.00 7.91   ? 181 PRO D CD    1 
ATOM   6784  N  N     . ILE D 1 182 ? 209.430 195.328 199.156 1.00 7.08   ? 182 ILE D N     1 
ATOM   6785  C  CA    . ILE D 1 182 ? 210.102 194.039 199.240 1.00 7.35   ? 182 ILE D CA    1 
ATOM   6786  C  C     . ILE D 1 182 ? 211.531 194.220 199.754 1.00 7.11   ? 182 ILE D C     1 
ATOM   6787  O  O     . ILE D 1 182 ? 212.005 193.420 200.549 1.00 7.52   ? 182 ILE D O     1 
ATOM   6788  C  CB    . ILE D 1 182 ? 210.044 193.309 197.891 1.00 7.55   ? 182 ILE D CB    1 
ATOM   6789  C  CG1   . ILE D 1 182 ? 208.617 192.966 197.512 1.00 7.78   ? 182 ILE D CG1   1 
ATOM   6790  C  CG2   . ILE D 1 182 ? 210.901 192.046 197.928 1.00 7.83   ? 182 ILE D CG2   1 
ATOM   6791  C  CD1   . ILE D 1 182 ? 208.504 192.340 196.138 1.00 8.17   ? 182 ILE D CD1   1 
ATOM   6792  N  N     . ALA D 1 183 ? 212.212 195.277 199.295 1.00 7.27   ? 183 ALA D N     1 
ATOM   6793  C  CA    . ALA D 1 183 ? 213.531 195.604 199.813 1.00 7.38   ? 183 ALA D CA    1 
ATOM   6794  C  C     . ALA D 1 183 ? 213.459 195.842 201.322 1.00 7.64   ? 183 ALA D C     1 
ATOM   6795  O  O     . ALA D 1 183 ? 214.323 195.378 202.064 1.00 7.94   ? 183 ALA D O     1 
ATOM   6796  C  CB    . ALA D 1 183 ? 214.123 196.785 199.081 1.00 7.13   ? 183 ALA D CB    1 
ATOM   6797  N  N     . ARG D 1 184 ? 212.431 196.571 201.767 1.00 8.25   ? 184 ARG D N     1 
ATOM   6798  C  CA    . ARG D 1 184 ? 212.211 196.765 203.191 1.00 9.40   ? 184 ARG D CA    1 
ATOM   6799  C  C     . ARG D 1 184 ? 211.874 195.446 203.886 1.00 9.72   ? 184 ARG D C     1 
ATOM   6800  O  O     . ARG D 1 184 ? 212.329 195.211 205.001 1.00 10.16  ? 184 ARG D O     1 
ATOM   6801  C  CB    . ARG D 1 184 ? 211.103 197.797 203.416 1.00 9.99   ? 184 ARG D CB    1 
ATOM   6802  C  CG    . ARG D 1 184 ? 211.533 199.203 203.036 1.00 10.64  ? 184 ARG D CG    1 
ATOM   6803  C  CD    . ARG D 1 184 ? 210.335 200.125 202.970 1.00 11.65  ? 184 ARG D CD    1 
ATOM   6804  N  NE    . ARG D 1 184 ? 210.735 201.529 203.025 1.00 11.98  ? 184 ARG D NE    1 
ATOM   6805  C  CZ    . ARG D 1 184 ? 209.913 202.559 203.097 1.00 12.79  ? 184 ARG D CZ    1 
ATOM   6806  N  NH1   . ARG D 1 184 ? 208.600 202.388 203.047 1.00 12.58  ? 184 ARG D NH1   1 
ATOM   6807  N  NH2   . ARG D 1 184 ? 210.427 203.773 203.215 1.00 13.42  ? 184 ARG D NH2   1 
ATOM   6808  N  N     . ASP D 1 185 ? 211.069 194.600 203.239 1.00 10.54  ? 185 ASP D N     1 
ATOM   6809  C  CA    . ASP D 1 185 ? 210.730 193.301 203.800 1.00 11.55  ? 185 ASP D CA    1 
ATOM   6810  C  C     . ASP D 1 185 ? 211.981 192.458 204.046 1.00 10.46  ? 185 ASP D C     1 
ATOM   6811  O  O     . ASP D 1 185 ? 212.120 191.856 205.106 1.00 10.54  ? 185 ASP D O     1 
ATOM   6812  C  CB    . ASP D 1 185 ? 209.822 192.521 202.862 1.00 13.80  ? 185 ASP D CB    1 
ATOM   6813  C  CG    . ASP D 1 185 ? 208.350 192.839 202.980 1.00 16.30  ? 185 ASP D CG    1 
ATOM   6814  O  OD1   . ASP D 1 185 ? 208.011 193.643 203.870 1.00 19.47  ? 185 ASP D OD1   1 
ATOM   6815  O  OD2   . ASP D 1 185 ? 207.566 192.275 202.172 1.00 18.80  ? 185 ASP D OD2   1 
ATOM   6816  N  N     . LEU D 1 186 ? 212.884 192.405 203.062 1.00 9.96   ? 186 LEU D N     1 
ATOM   6817  C  CA    . LEU D 1 186 ? 214.010 191.483 203.088 1.00 9.91   ? 186 LEU D CA    1 
ATOM   6818  C  C     . LEU D 1 186 ? 215.277 192.117 203.651 1.00 10.50  ? 186 LEU D C     1 
ATOM   6819  O  O     . LEU D 1 186 ? 216.303 191.432 203.733 1.00 10.58  ? 186 LEU D O     1 
ATOM   6820  C  CB    . LEU D 1 186 ? 214.263 190.962 201.679 1.00 9.49   ? 186 LEU D CB    1 
ATOM   6821  C  CG    . LEU D 1 186 ? 213.063 190.293 201.007 1.00 9.22   ? 186 LEU D CG    1 
ATOM   6822  C  CD1   . LEU D 1 186 ? 213.465 189.742 199.647 1.00 9.15   ? 186 LEU D CD1   1 
ATOM   6823  C  CD2   . LEU D 1 186 ? 212.459 189.214 201.869 1.00 9.27   ? 186 LEU D CD2   1 
ATOM   6824  N  N     . ALA D 1 187 ? 215.213 193.396 204.047 1.00 11.20  ? 187 ALA D N     1 
ATOM   6825  C  CA    . ALA D 1 187 ? 216.380 194.068 204.602 1.00 12.58  ? 187 ALA D CA    1 
ATOM   6826  C  C     . ALA D 1 187 ? 216.920 193.355 205.844 1.00 13.61  ? 187 ALA D C     1 
ATOM   6827  O  O     . ALA D 1 187 ? 218.133 193.192 205.946 1.00 15.03  ? 187 ALA D O     1 
ATOM   6828  C  CB    . ALA D 1 187 ? 216.057 195.522 204.902 1.00 12.11  ? 187 ALA D CB    1 
ATOM   6829  N  N     . PRO D 1 188 ? 216.107 192.926 206.836 1.00 16.37  ? 188 PRO D N     1 
ATOM   6830  C  CA    . PRO D 1 188 ? 216.663 192.179 207.972 1.00 18.04  ? 188 PRO D CA    1 
ATOM   6831  C  C     . PRO D 1 188 ? 217.368 190.886 207.573 1.00 18.63  ? 188 PRO D C     1 
ATOM   6832  O  O     . PRO D 1 188 ? 218.286 190.451 208.252 1.00 22.96  ? 188 PRO D O     1 
ATOM   6833  C  CB    . PRO D 1 188 ? 215.435 191.886 208.853 1.00 18.33  ? 188 PRO D CB    1 
ATOM   6834  C  CG    . PRO D 1 188 ? 214.408 192.900 208.436 1.00 18.59  ? 188 PRO D CG    1 
ATOM   6835  C  CD    . PRO D 1 188 ? 214.657 193.149 206.970 1.00 17.65  ? 188 PRO D CD    1 
ATOM   6836  N  N     . ILE D 1 189 ? 216.948 190.274 206.469 1.00 18.60  ? 189 ILE D N     1 
ATOM   6837  C  CA    . ILE D 1 189 ? 217.531 189.017 206.030 1.00 19.61  ? 189 ILE D CA    1 
ATOM   6838  C  C     . ILE D 1 189 ? 218.854 189.279 205.306 1.00 16.57  ? 189 ILE D C     1 
ATOM   6839  O  O     . ILE D 1 189 ? 219.689 188.382 205.215 1.00 18.07  ? 189 ILE D O     1 
ATOM   6840  C  CB    . ILE D 1 189 ? 216.520 188.266 205.138 1.00 23.16  ? 189 ILE D CB    1 
ATOM   6841  C  CG1   . ILE D 1 189 ? 215.275 187.924 205.889 1.00 28.02  ? 189 ILE D CG1   1 
ATOM   6842  C  CG2   . ILE D 1 189 ? 217.119 187.010 204.517 1.00 25.99  ? 189 ILE D CG2   1 
ATOM   6843  C  CD1   . ILE D 1 189 ? 214.255 187.186 205.040 1.00 29.98  ? 189 ILE D CD1   1 
ATOM   6844  N  N     . GLY D 1 190 ? 219.041 190.499 204.801 1.00 13.39  ? 190 GLY D N     1 
ATOM   6845  C  CA    . GLY D 1 190 ? 220.220 190.833 204.026 1.00 11.40  ? 190 GLY D CA    1 
ATOM   6846  C  C     . GLY D 1 190 ? 220.067 190.466 202.550 1.00 9.93   ? 190 GLY D C     1 
ATOM   6847  O  O     . GLY D 1 190 ? 221.050 190.079 201.920 1.00 9.60   ? 190 GLY D O     1 
ATOM   6848  N  N     . ILE D 1 191 ? 218.859 190.633 202.002 1.00 8.95   ? 191 ILE D N     1 
ATOM   6849  C  CA    . ILE D 1 191 ? 218.627 190.422 200.581 1.00 8.55   ? 191 ILE D CA    1 
ATOM   6850  C  C     . ILE D 1 191 ? 218.321 191.768 199.945 1.00 7.75   ? 191 ILE D C     1 
ATOM   6851  O  O     . ILE D 1 191 ? 217.314 192.384 200.265 1.00 7.90   ? 191 ILE D O     1 
ATOM   6852  C  CB    . ILE D 1 191 ? 217.491 189.414 200.337 1.00 8.56   ? 191 ILE D CB    1 
ATOM   6853  C  CG1   . ILE D 1 191 ? 217.807 188.060 200.958 1.00 8.70   ? 191 ILE D CG1   1 
ATOM   6854  C  CG2   . ILE D 1 191 ? 217.196 189.289 198.854 1.00 8.64   ? 191 ILE D CG2   1 
ATOM   6855  C  CD1   . ILE D 1 191 ? 216.646 187.090 200.935 1.00 8.72   ? 191 ILE D CD1   1 
ATOM   6856  N  N     . ARG D 1 192 ? 219.177 192.199 199.026 1.00 7.31   ? 192 ARG D N     1 
ATOM   6857  C  CA    . ARG D 1 192 ? 218.938 193.433 198.290 1.00 7.09   ? 192 ARG D CA    1 
ATOM   6858  C  C     . ARG D 1 192 ? 217.961 193.163 197.146 1.00 6.63   ? 192 ARG D C     1 
ATOM   6859  O  O     . ARG D 1 192 ? 218.035 192.134 196.483 1.00 6.53   ? 192 ARG D O     1 
ATOM   6860  C  CB    . ARG D 1 192 ? 220.252 193.997 197.737 1.00 7.00   ? 192 ARG D CB    1 
ATOM   6861  C  CG    . ARG D 1 192 ? 221.199 194.466 198.825 1.00 6.97   ? 192 ARG D CG    1 
ATOM   6862  C  CD    . ARG D 1 192 ? 222.354 195.261 198.262 1.00 7.01   ? 192 ARG D CD    1 
ATOM   6863  N  NE    . ARG D 1 192 ? 223.327 194.427 197.559 1.00 6.86   ? 192 ARG D NE    1 
ATOM   6864  C  CZ    . ARG D 1 192 ? 223.620 194.502 196.274 1.00 6.72   ? 192 ARG D CZ    1 
ATOM   6865  N  NH1   . ARG D 1 192 ? 223.006 195.358 195.476 1.00 6.52   ? 192 ARG D NH1   1 
ATOM   6866  N  NH2   . ARG D 1 192 ? 224.531 193.702 195.755 1.00 6.92   ? 192 ARG D NH2   1 
ATOM   6867  N  N     . VAL D 1 193 ? 217.063 194.126 196.922 1.00 6.43   ? 193 VAL D N     1 
ATOM   6868  C  CA    . VAL D 1 193 ? 216.079 194.033 195.863 1.00 6.42   ? 193 VAL D CA    1 
ATOM   6869  C  C     . VAL D 1 193 ? 216.229 195.259 194.977 1.00 6.33   ? 193 VAL D C     1 
ATOM   6870  O  O     . VAL D 1 193 ? 216.132 196.388 195.450 1.00 6.38   ? 193 VAL D O     1 
ATOM   6871  C  CB    . VAL D 1 193 ? 214.640 193.915 196.402 1.00 6.40   ? 193 VAL D CB    1 
ATOM   6872  C  CG1   . VAL D 1 193 ? 213.653 193.686 195.271 1.00 6.43   ? 193 VAL D CG1   1 
ATOM   6873  C  CG2   . VAL D 1 193 ? 214.531 192.796 197.429 1.00 6.51   ? 193 VAL D CG2   1 
ATOM   6874  N  N     . MET D 1 194 ? 216.476 195.028 193.693 1.00 6.43   ? 194 MET D N     1 
ATOM   6875  C  CA    . MET D 1 194 ? 216.727 196.092 192.742 1.00 6.84   ? 194 MET D CA    1 
ATOM   6876  C  C     . MET D 1 194 ? 215.914 195.815 191.487 1.00 6.85   ? 194 MET D C     1 
ATOM   6877  O  O     . MET D 1 194 ? 215.553 194.677 191.200 1.00 7.18   ? 194 MET D O     1 
ATOM   6878  C  CB    . MET D 1 194 ? 218.222 196.175 192.360 1.00 7.35   ? 194 MET D CB    1 
ATOM   6879  C  CG    . MET D 1 194 ? 219.086 196.922 193.363 1.00 7.92   ? 194 MET D CG    1 
ATOM   6880  S  SD    . MET D 1 194 ? 218.630 198.663 193.503 1.00 8.16   ? 194 MET D SD    1 
ATOM   6881  C  CE    . MET D 1 194 ? 219.177 199.291 191.916 1.00 8.63   ? 194 MET D CE    1 
ATOM   6882  N  N     . THR D 1 195 ? 215.621 196.881 190.743 1.00 6.71   ? 195 THR D N     1 
ATOM   6883  C  CA    . THR D 1 195 ? 214.851 196.779 189.522 1.00 7.14   ? 195 THR D CA    1 
ATOM   6884  C  C     . THR D 1 195 ? 215.571 197.539 188.417 1.00 7.10   ? 195 THR D C     1 
ATOM   6885  O  O     . THR D 1 195 ? 216.014 198.662 188.624 1.00 7.81   ? 195 THR D O     1 
ATOM   6886  C  CB    . THR D 1 195 ? 213.433 197.319 189.757 1.00 7.70   ? 195 THR D CB    1 
ATOM   6887  O  OG1   . THR D 1 195 ? 212.756 196.473 190.681 1.00 7.86   ? 195 THR D OG1   1 
ATOM   6888  C  CG2   . THR D 1 195 ? 212.648 197.396 188.461 1.00 7.84   ? 195 THR D CG2   1 
ATOM   6889  N  N     . ILE D 1 196 ? 215.627 196.932 187.237 1.00 7.32   ? 196 ILE D N     1 
ATOM   6890  C  CA    . ILE D 1 196 ? 216.117 197.584 186.035 1.00 7.61   ? 196 ILE D CA    1 
ATOM   6891  C  C     . ILE D 1 196 ? 214.923 197.862 185.133 1.00 7.82   ? 196 ILE D C     1 
ATOM   6892  O  O     . ILE D 1 196 ? 214.078 196.992 184.932 1.00 8.42   ? 196 ILE D O     1 
ATOM   6893  C  CB    . ILE D 1 196 ? 217.175 196.732 185.319 1.00 7.45   ? 196 ILE D CB    1 
ATOM   6894  C  CG1   . ILE D 1 196 ? 218.351 196.437 186.222 1.00 7.42   ? 196 ILE D CG1   1 
ATOM   6895  C  CG2   . ILE D 1 196 ? 217.622 197.402 184.022 1.00 7.38   ? 196 ILE D CG2   1 
ATOM   6896  C  CD1   . ILE D 1 196 ? 219.325 195.433 185.626 1.00 7.82   ? 196 ILE D CD1   1 
ATOM   6897  N  N     . ALA D 1 197 ? 214.858 199.085 184.615 1.00 8.08   ? 197 ALA D N     1 
ATOM   6898  C  CA    . ALA D 1 197 ? 213.817 199.473 183.689 1.00 8.65   ? 197 ALA D CA    1 
ATOM   6899  C  C     . ALA D 1 197 ? 214.432 199.689 182.314 1.00 9.30   ? 197 ALA D C     1 
ATOM   6900  O  O     . ALA D 1 197 ? 214.820 200.801 181.966 1.00 9.57   ? 197 ALA D O     1 
ATOM   6901  C  CB    . ALA D 1 197 ? 213.108 200.721 184.186 1.00 8.64   ? 197 ALA D CB    1 
ATOM   6902  N  N     . PRO D 1 198 ? 214.560 198.638 181.488 1.00 10.47  ? 198 PRO D N     1 
ATOM   6903  C  CA    . PRO D 1 198 ? 215.173 198.810 180.174 1.00 12.00  ? 198 PRO D CA    1 
ATOM   6904  C  C     . PRO D 1 198 ? 214.265 199.573 179.229 1.00 13.72  ? 198 PRO D C     1 
ATOM   6905  O  O     . PRO D 1 198 ? 213.049 199.562 179.389 1.00 13.55  ? 198 PRO D O     1 
ATOM   6906  C  CB    . PRO D 1 198 ? 215.420 197.376 179.704 1.00 11.98  ? 198 PRO D CB    1 
ATOM   6907  C  CG    . PRO D 1 198 ? 214.452 196.546 180.485 1.00 11.96  ? 198 PRO D CG    1 
ATOM   6908  C  CD    . PRO D 1 198 ? 214.215 197.245 181.797 1.00 11.19  ? 198 PRO D CD    1 
ATOM   6909  N  N     . GLY D 1 199 ? 214.858 200.185 178.195 1.00 17.82  ? 199 GLY D N     1 
ATOM   6910  C  CA    . GLY D 1 199 ? 214.054 200.747 177.120 1.00 21.59  ? 199 GLY D CA    1 
ATOM   6911  C  C     . GLY D 1 199 ? 214.563 200.378 175.733 1.00 28.10  ? 199 GLY D C     1 
ATOM   6912  O  O     . GLY D 1 199 ? 215.688 200.708 175.388 1.00 37.25  ? 199 GLY D O     1 
ATOM   6913  N  N     . LEU D 1 200 ? 213.747 199.702 174.927 1.00 31.36  ? 200 LEU D N     1 
ATOM   6914  C  CA    . LEU D 1 200 ? 214.057 199.426 173.530 1.00 29.56  ? 200 LEU D CA    1 
ATOM   6915  C  C     . LEU D 1 200 ? 215.387 198.693 173.369 1.00 26.84  ? 200 LEU D C     1 
ATOM   6916  O  O     . LEU D 1 200 ? 216.391 199.225 172.901 1.00 26.53  ? 200 LEU D O     1 
ATOM   6917  C  CB    . LEU D 1 200 ? 214.006 200.706 172.705 1.00 32.33  ? 200 LEU D CB    1 
ATOM   6918  C  CG    . LEU D 1 200 ? 212.640 201.388 172.601 1.00 36.45  ? 200 LEU D CG    1 
ATOM   6919  C  CD1   . LEU D 1 200 ? 212.734 202.476 171.527 1.00 37.60  ? 200 LEU D CD1   1 
ATOM   6920  C  CD2   . LEU D 1 200 ? 211.504 200.423 172.280 1.00 39.26  ? 200 LEU D CD2   1 
ATOM   6921  N  N     . PHE D 1 201 ? 215.350 197.415 173.715 1.00 25.21  ? 201 PHE D N     1 
ATOM   6922  C  CA    . PHE D 1 201 ? 216.485 196.522 173.547 1.00 25.76  ? 201 PHE D CA    1 
ATOM   6923  C  C     . PHE D 1 201 ? 216.292 195.615 172.342 1.00 29.78  ? 201 PHE D C     1 
ATOM   6924  O  O     . PHE D 1 201 ? 215.168 195.322 171.949 1.00 30.61  ? 201 PHE D O     1 
ATOM   6925  C  CB    . PHE D 1 201 ? 216.683 195.682 174.809 1.00 24.16  ? 201 PHE D CB    1 
ATOM   6926  C  CG    . PHE D 1 201 ? 217.612 196.349 175.804 1.00 22.17  ? 201 PHE D CG    1 
ATOM   6927  C  CD1   . PHE D 1 201 ? 217.209 197.481 176.495 1.00 22.02  ? 201 PHE D CD1   1 
ATOM   6928  C  CD2   . PHE D 1 201 ? 218.878 195.862 176.034 1.00 21.47  ? 201 PHE D CD2   1 
ATOM   6929  C  CE1   . PHE D 1 201 ? 218.059 198.115 177.380 1.00 21.94  ? 201 PHE D CE1   1 
ATOM   6930  C  CE2   . PHE D 1 201 ? 219.725 196.493 176.927 1.00 21.94  ? 201 PHE D CE2   1 
ATOM   6931  C  CZ    . PHE D 1 201 ? 219.321 197.619 177.586 1.00 21.55  ? 201 PHE D CZ    1 
ATOM   6932  N  N     . GLY D 1 202 ? 217.413 195.169 171.781 1.00 32.80  ? 202 GLY D N     1 
ATOM   6933  C  CA    . GLY D 1 202 ? 217.389 194.296 170.619 1.00 37.23  ? 202 GLY D CA    1 
ATOM   6934  C  C     . GLY D 1 202 ? 217.014 192.863 170.988 1.00 42.97  ? 202 GLY D C     1 
ATOM   6935  O  O     . GLY D 1 202 ? 217.744 191.930 170.658 1.00 47.44  ? 202 GLY D O     1 
ATOM   6936  N  N     . THR D 1 203 ? 215.878 192.699 171.668 1.00 51.85  ? 203 THR D N     1 
ATOM   6937  C  CA    . THR D 1 203 ? 215.396 191.377 172.022 1.00 60.96  ? 203 THR D CA    1 
ATOM   6938  C  C     . THR D 1 203 ? 214.479 190.888 170.908 1.00 73.81  ? 203 THR D C     1 
ATOM   6939  O  O     . THR D 1 203 ? 213.944 191.679 170.134 1.00 75.30  ? 203 THR D O     1 
ATOM   6940  C  CB    . THR D 1 203 ? 214.688 191.392 173.376 1.00 58.68  ? 203 THR D CB    1 
ATOM   6941  O  OG1   . THR D 1 203 ? 213.590 192.294 173.296 1.00 57.60  ? 203 THR D OG1   1 
ATOM   6942  C  CG2   . THR D 1 203 ? 215.620 191.827 174.485 1.00 57.85  ? 203 THR D CG2   1 
ATOM   6943  N  N     . PRO D 1 204 ? 214.242 189.560 170.810 1.00 92.32  ? 204 PRO D N     1 
ATOM   6944  C  CA    . PRO D 1 204 ? 213.271 189.043 169.845 1.00 101.12 ? 204 PRO D CA    1 
ATOM   6945  C  C     . PRO D 1 204 ? 211.877 189.648 169.966 1.00 104.96 ? 204 PRO D C     1 
ATOM   6946  O  O     . PRO D 1 204 ? 211.152 189.694 168.983 1.00 106.39 ? 204 PRO D O     1 
ATOM   6947  C  CB    . PRO D 1 204 ? 213.262 187.539 170.137 1.00 102.59 ? 204 PRO D CB    1 
ATOM   6948  C  CG    . PRO D 1 204 ? 214.628 187.272 170.713 1.00 100.85 ? 204 PRO D CG    1 
ATOM   6949  C  CD    . PRO D 1 204 ? 214.921 188.492 171.565 1.00 96.58  ? 204 PRO D CD    1 
ATOM   6950  N  N     . LEU D 1 205 ? 211.496 190.106 171.165 1.00 110.84 ? 205 LEU D N     1 
ATOM   6951  C  CA    . LEU D 1 205 ? 210.206 190.749 171.366 1.00 117.84 ? 205 LEU D CA    1 
ATOM   6952  C  C     . LEU D 1 205 ? 210.107 192.013 170.509 1.00 116.20 ? 205 LEU D C     1 
ATOM   6953  O  O     . LEU D 1 205 ? 209.097 192.239 169.838 1.00 120.05 ? 205 LEU D O     1 
ATOM   6954  C  CB    . LEU D 1 205 ? 210.000 191.044 172.853 1.00 125.51 ? 205 LEU D CB    1 
ATOM   6955  C  CG    . LEU D 1 205 ? 208.800 191.916 173.251 1.00 131.35 ? 205 LEU D CG    1 
ATOM   6956  C  CD1   . LEU D 1 205 ? 208.187 191.431 174.555 1.00 133.37 ? 205 LEU D CD1   1 
ATOM   6957  C  CD2   . LEU D 1 205 ? 209.182 193.390 173.384 1.00 133.28 ? 205 LEU D CD2   1 
ATOM   6958  N  N     . LEU D 1 206 ? 211.158 192.838 170.538 1.00 113.37 ? 206 LEU D N     1 
ATOM   6959  C  CA    . LEU D 1 206 ? 211.127 194.096 169.808 1.00 109.34 ? 206 LEU D CA    1 
ATOM   6960  C  C     . LEU D 1 206 ? 211.319 193.875 168.307 1.00 115.37 ? 206 LEU D C     1 
ATOM   6961  O  O     . LEU D 1 206 ? 210.804 194.646 167.501 1.00 118.28 ? 206 LEU D O     1 
ATOM   6962  C  CB    . LEU D 1 206 ? 212.167 195.061 170.360 1.00 99.77  ? 206 LEU D CB    1 
ATOM   6963  C  CG    . LEU D 1 206 ? 212.062 196.510 169.872 1.00 91.49  ? 206 LEU D CG    1 
ATOM   6964  C  CD1   . LEU D 1 206 ? 210.687 197.117 170.108 1.00 92.38  ? 206 LEU D CD1   1 
ATOM   6965  C  CD2   . LEU D 1 206 ? 213.112 197.380 170.530 1.00 88.07  ? 206 LEU D CD2   1 
ATOM   6966  N  N     . THR D 1 207 ? 212.040 192.818 167.934 1.00 122.20 ? 207 THR D N     1 
ATOM   6967  C  CA    . THR D 1 207 ? 212.225 192.497 166.524 1.00 130.06 ? 207 THR D CA    1 
ATOM   6968  C  C     . THR D 1 207 ? 210.924 191.959 165.923 1.00 138.76 ? 207 THR D C     1 
ATOM   6969  O  O     . THR D 1 207 ? 210.741 192.013 164.704 1.00 139.66 ? 207 THR D O     1 
ATOM   6970  C  CB    . THR D 1 207 ? 213.360 191.491 166.340 1.00 131.44 ? 207 THR D CB    1 
ATOM   6971  O  OG1   . THR D 1 207 ? 214.472 191.875 167.147 1.00 131.51 ? 207 THR D OG1   1 
ATOM   6972  C  CG2   . THR D 1 207 ? 213.783 191.380 164.887 1.00 130.43 ? 207 THR D CG2   1 
ATOM   6973  N  N     . SER D 1 208 ? 210.014 191.437 166.762 1.00 139.53 ? 208 SER D N     1 
ATOM   6974  C  CA    . SER D 1 208 ? 208.716 190.975 166.287 1.00 140.54 ? 208 SER D CA    1 
ATOM   6975  C  C     . SER D 1 208 ? 207.882 192.140 165.741 1.00 137.93 ? 208 SER D C     1 
ATOM   6976  O  O     . SER D 1 208 ? 206.983 191.922 164.932 1.00 138.83 ? 208 SER D O     1 
ATOM   6977  C  CB    . SER D 1 208 ? 207.962 190.241 167.350 1.00 141.96 ? 208 SER D CB    1 
ATOM   6978  O  OG    . SER D 1 208 ? 207.480 191.139 168.337 1.00 142.03 ? 208 SER D OG    1 
ATOM   6979  N  N     . LEU D 1 209 ? 208.193 193.375 166.166 1.00 132.95 ? 209 LEU D N     1 
ATOM   6980  C  CA    . LEU D 1 209 ? 207.561 194.552 165.599 1.00 126.64 ? 209 LEU D CA    1 
ATOM   6981  C  C     . LEU D 1 209 ? 207.981 194.712 164.144 1.00 124.59 ? 209 LEU D C     1 
ATOM   6982  O  O     . LEU D 1 209 ? 209.021 194.203 163.734 1.00 124.75 ? 209 LEU D O     1 
ATOM   6983  C  CB    . LEU D 1 209 ? 207.910 195.801 166.409 1.00 126.98 ? 209 LEU D CB    1 
ATOM   6984  C  CG    . LEU D 1 209 ? 207.093 196.040 167.683 1.00 128.90 ? 209 LEU D CG    1 
ATOM   6985  C  CD1   . LEU D 1 209 ? 207.503 197.360 168.323 1.00 125.09 ? 209 LEU D CD1   1 
ATOM   6986  C  CD2   . LEU D 1 209 ? 205.600 196.018 167.395 1.00 129.91 ? 209 LEU D CD2   1 
ATOM   6987  N  N     . PRO D 1 210 ? 207.190 195.436 163.323 1.00 120.69 ? 210 PRO D N     1 
ATOM   6988  C  CA    . PRO D 1 210 ? 207.606 195.743 161.956 1.00 117.65 ? 210 PRO D CA    1 
ATOM   6989  C  C     . PRO D 1 210 ? 208.967 196.427 161.925 1.00 112.05 ? 210 PRO D C     1 
ATOM   6990  O  O     . PRO D 1 210 ? 209.293 197.236 162.797 1.00 112.78 ? 210 PRO D O     1 
ATOM   6991  C  CB    . PRO D 1 210 ? 206.497 196.657 161.432 1.00 118.38 ? 210 PRO D CB    1 
ATOM   6992  C  CG    . PRO D 1 210 ? 205.301 196.304 162.282 1.00 118.17 ? 210 PRO D CG    1 
ATOM   6993  C  CD    . PRO D 1 210 ? 205.861 195.979 163.653 1.00 119.57 ? 210 PRO D CD    1 
ATOM   6994  N  N     . GLU D 1 211 ? 209.753 196.104 160.894 1.00 106.99 ? 211 GLU D N     1 
ATOM   6995  C  CA    . GLU D 1 211 ? 211.121 196.593 160.787 1.00 102.71 ? 211 GLU D CA    1 
ATOM   6996  C  C     . GLU D 1 211 ? 211.151 198.120 160.748 1.00 99.85  ? 211 GLU D C     1 
ATOM   6997  O  O     . GLU D 1 211 ? 212.034 198.733 161.345 1.00 100.24 ? 211 GLU D O     1 
ATOM   6998  C  CB    . GLU D 1 211 ? 211.803 195.998 159.558 1.00 101.96 ? 211 GLU D CB    1 
ATOM   6999  C  CG    . GLU D 1 211 ? 213.289 196.321 159.450 1.00 103.93 ? 211 GLU D CG    1 
ATOM   7000  C  CD    . GLU D 1 211 ? 213.619 197.694 158.895 1.00 105.51 ? 211 GLU D CD    1 
ATOM   7001  O  OE1   . GLU D 1 211 ? 212.848 198.170 158.035 1.00 104.71 ? 211 GLU D OE1   1 
ATOM   7002  O  OE2   . GLU D 1 211 ? 214.652 198.275 159.297 1.00 104.98 ? 211 GLU D OE2   1 
ATOM   7003  N  N     . LYS D 1 212 ? 210.167 198.725 160.073 1.00 98.39  ? 212 LYS D N     1 
ATOM   7004  C  CA    . LYS D 1 212 ? 210.115 200.172 159.960 1.00 102.90 ? 212 LYS D CA    1 
ATOM   7005  C  C     . LYS D 1 212 ? 209.921 200.817 161.329 1.00 98.55  ? 212 LYS D C     1 
ATOM   7006  O  O     . LYS D 1 212 ? 210.573 201.824 161.625 1.00 96.15  ? 212 LYS D O     1 
ATOM   7007  C  CB    . LYS D 1 212 ? 209.002 200.590 158.998 1.00 107.39 ? 212 LYS D CB    1 
ATOM   7008  C  CG    . LYS D 1 212 ? 209.367 200.424 157.534 1.00 107.98 ? 212 LYS D CG    1 
ATOM   7009  C  CD    . LYS D 1 212 ? 208.669 201.429 156.620 1.00 108.00 ? 212 LYS D CD    1 
ATOM   7010  C  CE    . LYS D 1 212 ? 208.904 202.843 157.068 1.00 107.59 ? 212 LYS D CE    1 
ATOM   7011  N  NZ    . LYS D 1 212 ? 208.502 203.832 156.061 1.00 104.59 ? 212 LYS D NZ    1 
ATOM   7012  N  N     . VAL D 1 213 ? 209.036 200.237 162.151 1.00 93.50  ? 213 VAL D N     1 
ATOM   7013  C  CA    . VAL D 1 213 ? 208.754 200.802 163.459 1.00 91.20  ? 213 VAL D CA    1 
ATOM   7014  C  C     . VAL D 1 213 ? 209.983 200.675 164.357 1.00 88.32  ? 213 VAL D C     1 
ATOM   7015  O  O     . VAL D 1 213 ? 210.368 201.645 164.996 1.00 83.64  ? 213 VAL D O     1 
ATOM   7016  C  CB    . VAL D 1 213 ? 207.522 200.134 164.093 1.00 89.66  ? 213 VAL D CB    1 
ATOM   7017  C  CG1   . VAL D 1 213 ? 207.381 200.488 165.574 1.00 86.66  ? 213 VAL D CG1   1 
ATOM   7018  C  CG2   . VAL D 1 213 ? 206.263 200.475 163.305 1.00 87.54  ? 213 VAL D CG2   1 
ATOM   7019  N  N     . CYS D 1 214 ? 210.605 199.497 164.381 1.00 88.75  ? 214 CYS D N     1 
ATOM   7020  C  CA    . CYS D 1 214 ? 211.731 199.283 165.283 1.00 90.95  ? 214 CYS D CA    1 
ATOM   7021  C  C     . CYS D 1 214 ? 212.930 200.124 164.846 1.00 82.21  ? 214 CYS D C     1 
ATOM   7022  O  O     . CYS D 1 214 ? 213.635 200.693 165.685 1.00 81.07  ? 214 CYS D O     1 
ATOM   7023  C  CB    . CYS D 1 214 ? 212.101 197.809 165.385 1.00 97.94  ? 214 CYS D CB    1 
ATOM   7024  S  SG    . CYS D 1 214 ? 212.878 197.136 163.894 1.00 114.02 ? 214 CYS D SG    1 
ATOM   7025  N  N     . ASN D 1 215 ? 213.180 200.194 163.537 1.00 73.69  ? 215 ASN D N     1 
ATOM   7026  C  CA    . ASN D 1 215 ? 214.287 200.988 163.014 1.00 70.22  ? 215 ASN D CA    1 
ATOM   7027  C  C     . ASN D 1 215 ? 214.085 202.470 163.326 1.00 61.07  ? 215 ASN D C     1 
ATOM   7028  O  O     . ASN D 1 215 ? 215.026 203.172 163.678 1.00 60.58  ? 215 ASN D O     1 
ATOM   7029  C  CB    . ASN D 1 215 ? 214.457 200.765 161.518 1.00 73.03  ? 215 ASN D CB    1 
ATOM   7030  C  CG    . ASN D 1 215 ? 215.723 201.373 160.964 1.00 76.52  ? 215 ASN D CG    1 
ATOM   7031  O  OD1   . ASN D 1 215 ? 216.493 202.018 161.686 1.00 77.33  ? 215 ASN D OD1   1 
ATOM   7032  N  ND2   . ASN D 1 215 ? 215.961 201.175 159.677 1.00 78.43  ? 215 ASN D ND2   1 
ATOM   7033  N  N     . PHE D 1 216 ? 212.848 202.951 163.199 1.00 51.26  ? 216 PHE D N     1 
ATOM   7034  C  CA    . PHE D 1 216 ? 212.527 204.307 163.617 1.00 45.95  ? 216 PHE D CA    1 
ATOM   7035  C  C     . PHE D 1 216 ? 212.765 204.481 165.123 1.00 44.82  ? 216 PHE D C     1 
ATOM   7036  O  O     . PHE D 1 216 ? 213.267 205.509 165.553 1.00 38.73  ? 216 PHE D O     1 
ATOM   7037  C  CB    . PHE D 1 216 ? 211.076 204.609 163.240 1.00 41.22  ? 216 PHE D CB    1 
ATOM   7038  C  CG    . PHE D 1 216 ? 210.484 205.773 164.009 1.00 39.04  ? 216 PHE D CG    1 
ATOM   7039  C  CD1   . PHE D 1 216 ? 210.845 207.073 163.699 1.00 37.79  ? 216 PHE D CD1   1 
ATOM   7040  C  CD2   . PHE D 1 216 ? 209.604 205.549 165.060 1.00 39.85  ? 216 PHE D CD2   1 
ATOM   7041  C  CE1   . PHE D 1 216 ? 210.312 208.133 164.410 1.00 40.50  ? 216 PHE D CE1   1 
ATOM   7042  C  CE2   . PHE D 1 216 ? 209.073 206.613 165.766 1.00 38.34  ? 216 PHE D CE2   1 
ATOM   7043  C  CZ    . PHE D 1 216 ? 209.422 207.901 165.436 1.00 39.63  ? 216 PHE D CZ    1 
ATOM   7044  N  N     . LEU D 1 217 ? 212.366 203.480 165.925 1.00 44.45  ? 217 LEU D N     1 
ATOM   7045  C  CA    . LEU D 1 217 ? 212.558 203.532 167.364 1.00 46.50  ? 217 LEU D CA    1 
ATOM   7046  C  C     . LEU D 1 217 ? 214.041 203.624 167.709 1.00 41.73  ? 217 LEU D C     1 
ATOM   7047  O  O     . LEU D 1 217 ? 214.392 204.301 168.661 1.00 41.21  ? 217 LEU D O     1 
ATOM   7048  C  CB    . LEU D 1 217 ? 211.926 202.301 168.018 1.00 48.88  ? 217 LEU D CB    1 
ATOM   7049  C  CG    . LEU D 1 217 ? 210.404 202.321 168.162 1.00 49.09  ? 217 LEU D CG    1 
ATOM   7050  C  CD1   . LEU D 1 217 ? 209.901 200.963 168.620 1.00 50.74  ? 217 LEU D CD1   1 
ATOM   7051  C  CD2   . LEU D 1 217 ? 209.968 203.417 169.104 1.00 52.04  ? 217 LEU D CD2   1 
ATOM   7052  N  N     . ALA D 1 218 ? 214.904 202.936 166.966 1.00 38.34  ? 218 ALA D N     1 
ATOM   7053  C  CA    . ALA D 1 218 ? 216.337 203.005 167.183 1.00 38.80  ? 218 ALA D CA    1 
ATOM   7054  C  C     . ALA D 1 218 ? 216.852 204.436 167.013 1.00 37.21  ? 218 ALA D C     1 
ATOM   7055  O  O     . ALA D 1 218 ? 217.670 204.899 167.808 1.00 37.77  ? 218 ALA D O     1 
ATOM   7056  C  CB    . ALA D 1 218 ? 217.052 202.051 166.258 1.00 40.29  ? 218 ALA D CB    1 
ATOM   7057  N  N     . SER D 1 219 ? 216.342 205.143 166.001 1.00 35.45  ? 219 SER D N     1 
ATOM   7058  C  CA    . SER D 1 219 ? 216.729 206.528 165.773 1.00 35.00  ? 219 SER D CA    1 
ATOM   7059  C  C     . SER D 1 219 ? 216.154 207.454 166.845 1.00 31.71  ? 219 SER D C     1 
ATOM   7060  O  O     . SER D 1 219 ? 216.620 208.578 167.000 1.00 31.63  ? 219 SER D O     1 
ATOM   7061  C  CB    . SER D 1 219 ? 216.329 207.000 164.398 1.00 35.66  ? 219 SER D CB    1 
ATOM   7062  O  OG    . SER D 1 219 ? 214.917 207.109 164.299 1.00 35.20  ? 219 SER D OG    1 
ATOM   7063  N  N     . GLN D 1 220 ? 215.135 207.005 167.578 1.00 31.54  ? 220 GLN D N     1 
ATOM   7064  C  CA    . GLN D 1 220 ? 214.509 207.838 168.596 1.00 33.60  ? 220 GLN D CA    1 
ATOM   7065  C  C     . GLN D 1 220 ? 215.269 207.812 169.925 1.00 29.58  ? 220 GLN D C     1 
ATOM   7066  O  O     . GLN D 1 220 ? 215.000 208.646 170.784 1.00 28.69  ? 220 GLN D O     1 
ATOM   7067  C  CB    . GLN D 1 220 ? 213.075 207.386 168.855 1.00 40.19  ? 220 GLN D CB    1 
ATOM   7068  C  CG    . GLN D 1 220 ? 212.134 207.640 167.691 1.00 44.25  ? 220 GLN D CG    1 
ATOM   7069  C  CD    . GLN D 1 220 ? 212.059 209.106 167.338 1.00 47.58  ? 220 GLN D CD    1 
ATOM   7070  O  OE1   . GLN D 1 220 ? 212.701 209.576 166.397 1.00 49.71  ? 220 GLN D OE1   1 
ATOM   7071  N  NE2   . GLN D 1 220 ? 211.271 209.863 168.090 1.00 52.93  ? 220 GLN D NE2   1 
ATOM   7072  N  N     . VAL D 1 221 ? 216.205 206.873 170.106 1.00 25.78  ? 221 VAL D N     1 
ATOM   7073  C  CA    . VAL D 1 221 ? 217.038 206.883 171.292 1.00 23.59  ? 221 VAL D CA    1 
ATOM   7074  C  C     . VAL D 1 221 ? 218.050 208.014 171.161 1.00 22.49  ? 221 VAL D C     1 
ATOM   7075  O  O     . VAL D 1 221 ? 218.788 208.064 170.188 1.00 23.61  ? 221 VAL D O     1 
ATOM   7076  C  CB    . VAL D 1 221 ? 217.734 205.531 171.499 1.00 22.87  ? 221 VAL D CB    1 
ATOM   7077  C  CG1   . VAL D 1 221 ? 218.503 205.499 172.815 1.00 21.46  ? 221 VAL D CG1   1 
ATOM   7078  C  CG2   . VAL D 1 221 ? 216.720 204.396 171.467 1.00 22.09  ? 221 VAL D CG2   1 
ATOM   7079  N  N     . PRO D 1 222 ? 218.086 208.986 172.098 1.00 20.98  ? 222 PRO D N     1 
ATOM   7080  C  CA    . PRO D 1 222 ? 218.999 210.122 171.978 1.00 20.83  ? 222 PRO D CA    1 
ATOM   7081  C  C     . PRO D 1 222 ? 220.454 209.725 171.768 1.00 20.92  ? 222 PRO D C     1 
ATOM   7082  O  O     . PRO D 1 222 ? 221.055 210.126 170.774 1.00 20.69  ? 222 PRO D O     1 
ATOM   7083  C  CB    . PRO D 1 222 ? 218.790 210.893 173.284 1.00 20.64  ? 222 PRO D CB    1 
ATOM   7084  C  CG    . PRO D 1 222 ? 217.376 210.561 173.645 1.00 21.12  ? 222 PRO D CG    1 
ATOM   7085  C  CD    . PRO D 1 222 ? 217.186 209.107 173.257 1.00 20.86  ? 222 PRO D CD    1 
ATOM   7086  N  N     . PHE D 1 223 ? 221.020 208.955 172.704 1.00 19.24  ? 223 PHE D N     1 
ATOM   7087  C  CA    . PHE D 1 223 ? 222.369 208.444 172.505 1.00 20.02  ? 223 PHE D CA    1 
ATOM   7088  C  C     . PHE D 1 223 ? 222.625 207.261 173.437 1.00 20.77  ? 223 PHE D C     1 
ATOM   7089  O  O     . PHE D 1 223 ? 222.361 207.349 174.634 1.00 22.62  ? 223 PHE D O     1 
ATOM   7090  C  CB    . PHE D 1 223 ? 223.448 209.518 172.715 1.00 19.35  ? 223 PHE D CB    1 
ATOM   7091  C  CG    . PHE D 1 223 ? 224.841 208.992 172.422 1.00 21.59  ? 223 PHE D CG    1 
ATOM   7092  C  CD1   . PHE D 1 223 ? 225.291 208.871 171.107 1.00 22.73  ? 223 PHE D CD1   1 
ATOM   7093  C  CD2   . PHE D 1 223 ? 225.680 208.563 173.445 1.00 21.94  ? 223 PHE D CD2   1 
ATOM   7094  C  CE1   . PHE D 1 223 ? 226.538 208.324 170.835 1.00 22.12  ? 223 PHE D CE1   1 
ATOM   7095  C  CE2   . PHE D 1 223 ? 226.913 207.996 173.164 1.00 22.85  ? 223 PHE D CE2   1 
ATOM   7096  C  CZ    . PHE D 1 223 ? 227.341 207.881 171.858 1.00 23.32  ? 223 PHE D CZ    1 
ATOM   7097  N  N     . PRO D 1 224 ? 223.165 206.126 172.945 1.00 22.33  ? 224 PRO D N     1 
ATOM   7098  C  CA    . PRO D 1 224 ? 223.431 205.887 171.521 1.00 23.95  ? 224 PRO D CA    1 
ATOM   7099  C  C     . PRO D 1 224 ? 222.154 205.629 170.730 1.00 24.50  ? 224 PRO D C     1 
ATOM   7100  O  O     . PRO D 1 224 ? 221.244 204.980 171.234 1.00 26.75  ? 224 PRO D O     1 
ATOM   7101  C  CB    . PRO D 1 224 ? 224.376 204.673 171.534 1.00 23.64  ? 224 PRO D CB    1 
ATOM   7102  C  CG    . PRO D 1 224 ? 224.001 203.936 172.788 1.00 24.28  ? 224 PRO D CG    1 
ATOM   7103  C  CD    . PRO D 1 224 ? 223.606 205.009 173.784 1.00 23.02  ? 224 PRO D CD    1 
ATOM   7104  N  N     . SER D 1 225 ? 222.091 206.137 169.491 1.00 26.56  ? 225 SER D N     1 
ATOM   7105  C  CA    . SER D 1 225 ? 220.892 206.030 168.676 1.00 26.74  ? 225 SER D CA    1 
ATOM   7106  C  C     . SER D 1 225 ? 220.825 204.633 168.062 1.00 26.79  ? 225 SER D C     1 
ATOM   7107  O  O     . SER D 1 225 ? 220.974 204.442 166.859 1.00 28.49  ? 225 SER D O     1 
ATOM   7108  C  CB    . SER D 1 225 ? 220.838 207.109 167.627 1.00 27.51  ? 225 SER D CB    1 
ATOM   7109  O  OG    . SER D 1 225 ? 221.008 208.392 168.204 1.00 29.21  ? 225 SER D OG    1 
ATOM   7110  N  N     . ARG D 1 226 ? 220.586 203.651 168.927 1.00 25.32  ? 226 ARG D N     1 
ATOM   7111  C  CA    . ARG D 1 226 ? 220.459 202.273 168.518 1.00 25.16  ? 226 ARG D CA    1 
ATOM   7112  C  C     . ARG D 1 226 ? 219.660 201.548 169.590 1.00 23.92  ? 226 ARG D C     1 
ATOM   7113  O  O     . ARG D 1 226 ? 219.497 202.039 170.706 1.00 23.05  ? 226 ARG D O     1 
ATOM   7114  C  CB    . ARG D 1 226 ? 221.835 201.632 168.322 1.00 27.63  ? 226 ARG D CB    1 
ATOM   7115  C  CG    . ARG D 1 226 ? 222.730 201.698 169.554 1.00 28.84  ? 226 ARG D CG    1 
ATOM   7116  C  CD    . ARG D 1 226 ? 223.853 200.704 169.480 1.00 31.14  ? 226 ARG D CD    1 
ATOM   7117  N  NE    . ARG D 1 226 ? 224.743 200.793 170.641 1.00 34.09  ? 226 ARG D NE    1 
ATOM   7118  C  CZ    . ARG D 1 226 ? 224.514 200.259 171.839 1.00 35.75  ? 226 ARG D CZ    1 
ATOM   7119  N  NH1   . ARG D 1 226 ? 223.408 199.577 172.069 1.00 33.25  ? 226 ARG D NH1   1 
ATOM   7120  N  NH2   . ARG D 1 226 ? 225.410 200.399 172.798 1.00 36.73  ? 226 ARG D NH2   1 
ATOM   7121  N  N     . LEU D 1 227 ? 219.183 200.363 169.241 1.00 22.54  ? 227 LEU D N     1 
ATOM   7122  C  CA    . LEU D 1 227 ? 218.508 199.534 170.216 1.00 23.03  ? 227 LEU D CA    1 
ATOM   7123  C  C     . LEU D 1 227 ? 219.516 199.089 171.269 1.00 23.62  ? 227 LEU D C     1 
ATOM   7124  O  O     . LEU D 1 227 ? 220.688 198.852 170.979 1.00 22.68  ? 227 LEU D O     1 
ATOM   7125  C  CB    . LEU D 1 227 ? 217.847 198.341 169.532 1.00 24.75  ? 227 LEU D CB    1 
ATOM   7126  C  CG    . LEU D 1 227 ? 216.682 198.669 168.595 1.00 26.05  ? 227 LEU D CG    1 
ATOM   7127  C  CD1   . LEU D 1 227 ? 216.000 197.383 168.162 1.00 27.69  ? 227 LEU D CD1   1 
ATOM   7128  C  CD2   . LEU D 1 227 ? 215.691 199.618 169.227 1.00 27.21  ? 227 LEU D CD2   1 
ATOM   7129  N  N     . GLY D 1 228 ? 219.013 198.909 172.493 1.00 23.89  ? 228 GLY D N     1 
ATOM   7130  C  CA    . GLY D 1 228 ? 219.854 198.426 173.567 1.00 22.42  ? 228 GLY D CA    1 
ATOM   7131  C  C     . GLY D 1 228 ? 220.420 197.035 173.279 1.00 21.69  ? 228 GLY D C     1 
ATOM   7132  O  O     . GLY D 1 228 ? 219.701 196.132 172.872 1.00 23.07  ? 228 GLY D O     1 
ATOM   7133  N  N     . ASP D 1 229 ? 221.721 196.872 173.529 1.00 22.38  ? 229 ASP D N     1 
ATOM   7134  C  CA    . ASP D 1 229 ? 222.349 195.573 173.422 1.00 23.89  ? 229 ASP D CA    1 
ATOM   7135  C  C     . ASP D 1 229 ? 222.059 194.769 174.687 1.00 22.14  ? 229 ASP D C     1 
ATOM   7136  O  O     . ASP D 1 229 ? 222.280 195.257 175.799 1.00 21.08  ? 229 ASP D O     1 
ATOM   7137  C  CB    . ASP D 1 229 ? 223.839 195.732 173.210 1.00 26.99  ? 229 ASP D CB    1 
ATOM   7138  C  CG    . ASP D 1 229 ? 224.559 194.474 172.771 1.00 31.16  ? 229 ASP D CG    1 
ATOM   7139  O  OD1   . ASP D 1 229 ? 224.019 193.370 172.969 1.00 31.30  ? 229 ASP D OD1   1 
ATOM   7140  O  OD2   . ASP D 1 229 ? 225.674 194.623 172.232 1.00 36.91  ? 229 ASP D OD2   1 
ATOM   7141  N  N     . PRO D 1 230 ? 221.524 193.536 174.586 1.00 19.79  ? 230 PRO D N     1 
ATOM   7142  C  CA    . PRO D 1 230 ? 221.269 192.730 175.778 1.00 18.84  ? 230 PRO D CA    1 
ATOM   7143  C  C     . PRO D 1 230 ? 222.476 192.550 176.692 1.00 16.85  ? 230 PRO D C     1 
ATOM   7144  O  O     . PRO D 1 230 ? 222.304 192.400 177.899 1.00 15.63  ? 230 PRO D O     1 
ATOM   7145  C  CB    . PRO D 1 230 ? 220.776 191.396 175.214 1.00 19.47  ? 230 PRO D CB    1 
ATOM   7146  C  CG    . PRO D 1 230 ? 220.126 191.791 173.910 1.00 20.73  ? 230 PRO D CG    1 
ATOM   7147  C  CD    . PRO D 1 230 ? 221.010 192.897 173.367 1.00 20.77  ? 230 PRO D CD    1 
ATOM   7148  N  N     . ALA D 1 231 ? 223.690 192.558 176.125 1.00 15.95  ? 231 ALA D N     1 
ATOM   7149  C  CA    . ALA D 1 231 ? 224.904 192.509 176.928 1.00 15.57  ? 231 ALA D CA    1 
ATOM   7150  C  C     . ALA D 1 231 ? 225.014 193.723 177.857 1.00 14.76  ? 231 ALA D C     1 
ATOM   7151  O  O     . ALA D 1 231 ? 225.559 193.619 178.947 1.00 15.34  ? 231 ALA D O     1 
ATOM   7152  C  CB    . ALA D 1 231 ? 226.118 192.403 176.039 1.00 15.64  ? 231 ALA D CB    1 
ATOM   7153  N  N     . GLU D 1 232 ? 224.490 194.869 177.436 1.00 14.47  ? 232 GLU D N     1 
ATOM   7154  C  CA    . GLU D 1 232 ? 224.488 196.057 178.276 1.00 14.95  ? 232 GLU D CA    1 
ATOM   7155  C  C     . GLU D 1 232 ? 223.572 195.869 179.483 1.00 12.44  ? 232 GLU D C     1 
ATOM   7156  O  O     . GLU D 1 232 ? 223.879 196.346 180.570 1.00 11.82  ? 232 GLU D O     1 
ATOM   7157  C  CB    . GLU D 1 232 ? 224.070 197.284 177.467 1.00 16.72  ? 232 GLU D CB    1 
ATOM   7158  C  CG    . GLU D 1 232 ? 225.224 197.848 176.645 1.00 20.23  ? 232 GLU D CG    1 
ATOM   7159  C  CD    . GLU D 1 232 ? 224.824 198.337 175.271 1.00 22.90  ? 232 GLU D CD    1 
ATOM   7160  O  OE1   . GLU D 1 232 ? 225.688 198.238 174.365 1.00 27.23  ? 232 GLU D OE1   1 
ATOM   7161  O  OE2   . GLU D 1 232 ? 223.665 198.739 175.102 1.00 22.51  ? 232 GLU D OE2   1 
ATOM   7162  N  N     . TYR D 1 233 ? 222.457 195.171 179.292 1.00 10.87  ? 233 TYR D N     1 
ATOM   7163  C  CA    . TYR D 1 233 ? 221.610 194.805 180.415 1.00 10.38  ? 233 TYR D CA    1 
ATOM   7164  C  C     . TYR D 1 233 ? 222.382 193.890 181.360 1.00 9.64   ? 233 TYR D C     1 
ATOM   7165  O  O     . TYR D 1 233 ? 222.307 194.053 182.578 1.00 8.90   ? 233 TYR D O     1 
ATOM   7166  C  CB    . TYR D 1 233 ? 220.318 194.152 179.916 1.00 10.91  ? 233 TYR D CB    1 
ATOM   7167  C  CG    . TYR D 1 233 ? 219.431 193.624 181.027 1.00 11.26  ? 233 TYR D CG    1 
ATOM   7168  C  CD1   . TYR D 1 233 ? 218.427 194.414 181.565 1.00 11.97  ? 233 TYR D CD1   1 
ATOM   7169  C  CD2   . TYR D 1 233 ? 219.579 192.336 181.515 1.00 12.00  ? 233 TYR D CD2   1 
ATOM   7170  C  CE1   . TYR D 1 233 ? 217.600 193.943 182.569 1.00 12.19  ? 233 TYR D CE1   1 
ATOM   7171  C  CE2   . TYR D 1 233 ? 218.763 191.850 182.519 1.00 12.87  ? 233 TYR D CE2   1 
ATOM   7172  C  CZ    . TYR D 1 233 ? 217.776 192.660 183.050 1.00 13.07  ? 233 TYR D CZ    1 
ATOM   7173  O  OH    . TYR D 1 233 ? 216.971 192.180 184.041 1.00 14.19  ? 233 TYR D OH    1 
ATOM   7174  N  N     . ALA D 1 234 ? 223.092 192.904 180.800 1.00 9.37   ? 234 ALA D N     1 
ATOM   7175  C  CA    . ALA D 1 234 ? 223.865 191.966 181.602 1.00 9.37   ? 234 ALA D CA    1 
ATOM   7176  C  C     . ALA D 1 234 ? 224.938 192.697 182.409 1.00 9.48   ? 234 ALA D C     1 
ATOM   7177  O  O     . ALA D 1 234 ? 225.184 192.367 183.567 1.00 9.69   ? 234 ALA D O     1 
ATOM   7178  C  CB    . ALA D 1 234 ? 224.478 190.894 180.726 1.00 9.02   ? 234 ALA D CB    1 
ATOM   7179  N  N     . HIS D 1 235 ? 225.581 193.686 181.788 1.00 9.82   ? 235 HIS D N     1 
ATOM   7180  C  CA    . HIS D 1 235 ? 226.602 194.464 182.469 1.00 10.31  ? 235 HIS D CA    1 
ATOM   7181  C  C     . HIS D 1 235 ? 226.025 195.183 183.686 1.00 8.95   ? 235 HIS D C     1 
ATOM   7182  O  O     . HIS D 1 235 ? 226.647 195.210 184.743 1.00 8.52   ? 235 HIS D O     1 
ATOM   7183  C  CB    . HIS D 1 235 ? 227.243 195.461 181.496 1.00 11.55  ? 235 HIS D CB    1 
ATOM   7184  C  CG    . HIS D 1 235 ? 228.280 196.328 182.124 1.00 13.71  ? 235 HIS D CG    1 
ATOM   7185  N  ND1   . HIS D 1 235 ? 227.964 197.499 182.792 1.00 15.34  ? 235 HIS D ND1   1 
ATOM   7186  C  CD2   . HIS D 1 235 ? 229.617 196.186 182.219 1.00 14.79  ? 235 HIS D CD2   1 
ATOM   7187  C  CE1   . HIS D 1 235 ? 229.078 198.038 183.273 1.00 15.98  ? 235 HIS D CE1   1 
ATOM   7188  N  NE2   . HIS D 1 235 ? 230.092 197.268 182.923 1.00 15.75  ? 235 HIS D NE2   1 
ATOM   7189  N  N     . LEU D 1 236 ? 224.844 195.788 183.536 1.00 8.21   ? 236 LEU D N     1 
ATOM   7190  C  CA    . LEU D 1 236 ? 224.214 196.478 184.649 1.00 7.97   ? 236 LEU D CA    1 
ATOM   7191  C  C     . LEU D 1 236 ? 223.846 195.492 185.755 1.00 7.73   ? 236 LEU D C     1 
ATOM   7192  O  O     . LEU D 1 236 ? 223.955 195.817 186.932 1.00 7.65   ? 236 LEU D O     1 
ATOM   7193  C  CB    . LEU D 1 236 ? 222.999 197.269 184.174 1.00 8.19   ? 236 LEU D CB    1 
ATOM   7194  C  CG    . LEU D 1 236 ? 222.213 198.020 185.254 1.00 8.67   ? 236 LEU D CG    1 
ATOM   7195  C  CD1   . LEU D 1 236 ? 223.131 198.948 186.034 1.00 8.89   ? 236 LEU D CD1   1 
ATOM   7196  C  CD2   . LEU D 1 236 ? 221.062 198.796 184.643 1.00 8.94   ? 236 LEU D CD2   1 
ATOM   7197  N  N     . VAL D 1 237 ? 223.373 194.297 185.381 1.00 7.77   ? 237 VAL D N     1 
ATOM   7198  C  CA    . VAL D 1 237 ? 223.033 193.290 186.367 1.00 7.89   ? 237 VAL D CA    1 
ATOM   7199  C  C     . VAL D 1 237 ? 224.257 192.958 187.214 1.00 8.24   ? 237 VAL D C     1 
ATOM   7200  O  O     . VAL D 1 237 ? 224.175 192.874 188.435 1.00 8.36   ? 237 VAL D O     1 
ATOM   7201  C  CB    . VAL D 1 237 ? 222.457 192.025 185.697 1.00 7.98   ? 237 VAL D CB    1 
ATOM   7202  C  CG1   . VAL D 1 237 ? 222.472 190.847 186.648 1.00 8.23   ? 237 VAL D CG1   1 
ATOM   7203  C  CG2   . VAL D 1 237 ? 221.061 192.274 185.162 1.00 8.01   ? 237 VAL D CG2   1 
ATOM   7204  N  N     . GLN D 1 238 ? 225.405 192.744 186.567 1.00 8.83   ? 238 GLN D N     1 
ATOM   7205  C  CA    . GLN D 1 238 ? 226.622 192.461 187.300 1.00 9.63   ? 238 GLN D CA    1 
ATOM   7206  C  C     . GLN D 1 238 ? 227.021 193.625 188.211 1.00 8.66   ? 238 GLN D C     1 
ATOM   7207  O  O     . GLN D 1 238 ? 227.447 193.418 189.343 1.00 8.56   ? 238 GLN D O     1 
ATOM   7208  C  CB    . GLN D 1 238 ? 227.755 192.129 186.333 1.00 11.00  ? 238 GLN D CB    1 
ATOM   7209  C  CG    . GLN D 1 238 ? 229.060 191.779 187.040 1.00 13.00  ? 238 GLN D CG    1 
ATOM   7210  C  CD    . GLN D 1 238 ? 230.143 191.336 186.082 1.00 15.01  ? 238 GLN D CD    1 
ATOM   7211  O  OE1   . GLN D 1 238 ? 229.910 191.166 184.883 1.00 15.53  ? 238 GLN D OE1   1 
ATOM   7212  N  NE2   . GLN D 1 238 ? 231.335 191.134 186.616 1.00 15.76  ? 238 GLN D NE2   1 
ATOM   7213  N  N     . ALA D 1 239 ? 226.881 194.856 187.719 1.00 8.30   ? 239 ALA D N     1 
ATOM   7214  C  CA    . ALA D 1 239 ? 227.193 196.030 188.527 1.00 8.12   ? 239 ALA D CA    1 
ATOM   7215  C  C     . ALA D 1 239 ? 226.323 196.065 189.787 1.00 8.05   ? 239 ALA D C     1 
ATOM   7216  O  O     . ALA D 1 239 ? 226.815 196.389 190.863 1.00 8.17   ? 239 ALA D O     1 
ATOM   7217  C  CB    . ALA D 1 239 ? 227.033 197.281 187.706 1.00 8.40   ? 239 ALA D CB    1 
ATOM   7218  N  N     . ILE D 1 240 ? 225.032 195.721 189.655 1.00 7.85   ? 240 ILE D N     1 
ATOM   7219  C  CA    . ILE D 1 240 ? 224.143 195.703 190.799 1.00 8.12   ? 240 ILE D CA    1 
ATOM   7220  C  C     . ILE D 1 240 ? 224.569 194.630 191.796 1.00 7.88   ? 240 ILE D C     1 
ATOM   7221  O  O     . ILE D 1 240 ? 224.573 194.858 193.006 1.00 7.49   ? 240 ILE D O     1 
ATOM   7222  C  CB    . ILE D 1 240 ? 222.680 195.531 190.360 1.00 8.49   ? 240 ILE D CB    1 
ATOM   7223  C  CG1   . ILE D 1 240 ? 222.185 196.736 189.590 1.00 8.67   ? 240 ILE D CG1   1 
ATOM   7224  C  CG2   . ILE D 1 240 ? 221.786 195.227 191.566 1.00 8.75   ? 240 ILE D CG2   1 
ATOM   7225  C  CD1   . ILE D 1 240 ? 220.868 196.493 188.877 1.00 9.00   ? 240 ILE D CD1   1 
ATOM   7226  N  N     . ILE D 1 241 ? 224.926 193.446 191.283 1.00 8.46   ? 241 ILE D N     1 
ATOM   7227  C  CA    . ILE D 1 241 ? 225.350 192.357 192.151 1.00 9.18   ? 241 ILE D CA    1 
ATOM   7228  C  C     . ILE D 1 241 ? 226.608 192.766 192.920 1.00 9.75   ? 241 ILE D C     1 
ATOM   7229  O  O     . ILE D 1 241 ? 226.711 192.514 194.121 1.00 10.71  ? 241 ILE D O     1 
ATOM   7230  C  CB    . ILE D 1 241 ? 225.582 191.069 191.340 1.00 9.45   ? 241 ILE D CB    1 
ATOM   7231  C  CG1   . ILE D 1 241 ? 224.292 190.563 190.723 1.00 9.59   ? 241 ILE D CG1   1 
ATOM   7232  C  CG2   . ILE D 1 241 ? 226.236 189.992 192.212 1.00 9.83   ? 241 ILE D CG2   1 
ATOM   7233  C  CD1   . ILE D 1 241 ? 224.510 189.547 189.621 1.00 9.48   ? 241 ILE D CD1   1 
ATOM   7234  N  N     . GLU D 1 242 ? 227.562 193.399 192.241 1.00 11.07  ? 242 GLU D N     1 
ATOM   7235  C  CA    . GLU D 1 242 ? 228.843 193.718 192.851 1.00 12.93  ? 242 GLU D CA    1 
ATOM   7236  C  C     . GLU D 1 242 ? 228.754 194.888 193.831 1.00 12.36  ? 242 GLU D C     1 
ATOM   7237  O  O     . GLU D 1 242 ? 229.548 194.957 194.764 1.00 13.93  ? 242 GLU D O     1 
ATOM   7238  C  CB    . GLU D 1 242 ? 229.872 194.040 191.774 1.00 15.78  ? 242 GLU D CB    1 
ATOM   7239  C  CG    . GLU D 1 242 ? 230.313 192.820 190.977 1.00 19.27  ? 242 GLU D CG    1 
ATOM   7240  C  CD    . GLU D 1 242 ? 231.143 193.215 189.761 1.00 24.35  ? 242 GLU D CD    1 
ATOM   7241  O  OE1   . GLU D 1 242 ? 231.115 194.416 189.385 1.00 28.95  ? 242 GLU D OE1   1 
ATOM   7242  O  OE2   . GLU D 1 242 ? 231.765 192.316 189.148 1.00 27.09  ? 242 GLU D OE2   1 
ATOM   7243  N  N     . ASN D 1 243 ? 227.806 195.807 193.639 1.00 11.32  ? 243 ASN D N     1 
ATOM   7244  C  CA    . ASN D 1 243 ? 227.745 197.015 194.446 1.00 10.60  ? 243 ASN D CA    1 
ATOM   7245  C  C     . ASN D 1 243 ? 226.878 196.750 195.666 1.00 11.14  ? 243 ASN D C     1 
ATOM   7246  O  O     . ASN D 1 243 ? 225.669 196.591 195.519 1.00 12.20  ? 243 ASN D O     1 
ATOM   7247  C  CB    . ASN D 1 243 ? 227.202 198.197 193.649 1.00 10.21  ? 243 ASN D CB    1 
ATOM   7248  C  CG    . ASN D 1 243 ? 227.489 199.524 194.327 1.00 9.79   ? 243 ASN D CG    1 
ATOM   7249  O  OD1   . ASN D 1 243 ? 227.035 199.749 195.446 1.00 9.80   ? 243 ASN D OD1   1 
ATOM   7250  N  ND2   . ASN D 1 243 ? 228.245 200.408 193.701 1.00 9.60   ? 243 ASN D ND2   1 
ATOM   7251  N  N     . PRO D 1 244 ? 227.434 196.698 196.891 1.00 11.67  ? 244 PRO D N     1 
ATOM   7252  C  CA    . PRO D 1 244 ? 226.644 196.346 198.067 1.00 11.29  ? 244 PRO D CA    1 
ATOM   7253  C  C     . PRO D 1 244 ? 225.615 197.379 198.516 1.00 10.72  ? 244 PRO D C     1 
ATOM   7254  O  O     . PRO D 1 244 ? 224.792 197.077 199.366 1.00 11.10  ? 244 PRO D O     1 
ATOM   7255  C  CB    . PRO D 1 244 ? 227.711 196.171 199.167 1.00 12.30  ? 244 PRO D CB    1 
ATOM   7256  C  CG    . PRO D 1 244 ? 229.040 196.181 198.460 1.00 12.71  ? 244 PRO D CG    1 
ATOM   7257  C  CD    . PRO D 1 244 ? 228.848 196.954 197.210 1.00 12.48  ? 244 PRO D CD    1 
ATOM   7258  N  N     . PHE D 1 245 ? 225.654 198.591 197.954 1.00 9.72   ? 245 PHE D N     1 
ATOM   7259  C  CA    . PHE D 1 245 ? 224.867 199.670 198.517 1.00 9.14   ? 245 PHE D CA    1 
ATOM   7260  C  C     . PHE D 1 245 ? 223.706 200.088 197.625 1.00 8.56   ? 245 PHE D C     1 
ATOM   7261  O  O     . PHE D 1 245 ? 222.979 201.013 197.998 1.00 9.03   ? 245 PHE D O     1 
ATOM   7262  C  CB    . PHE D 1 245 ? 225.777 200.866 198.793 1.00 9.39   ? 245 PHE D CB    1 
ATOM   7263  C  CG    . PHE D 1 245 ? 225.276 201.708 199.947 1.00 9.57   ? 245 PHE D CG    1 
ATOM   7264  C  CD1   . PHE D 1 245 ? 225.265 201.206 201.238 1.00 9.99   ? 245 PHE D CD1   1 
ATOM   7265  C  CD2   . PHE D 1 245 ? 224.793 202.976 199.718 1.00 9.94   ? 245 PHE D CD2   1 
ATOM   7266  C  CE1   . PHE D 1 245 ? 224.842 202.010 202.305 1.00 10.04  ? 245 PHE D CE1   1 
ATOM   7267  C  CE2   . PHE D 1 245 ? 224.361 203.758 200.764 1.00 10.00  ? 245 PHE D CE2   1 
ATOM   7268  C  CZ    . PHE D 1 245 ? 224.414 203.293 202.064 1.00 9.91   ? 245 PHE D CZ    1 
ATOM   7269  N  N     . LEU D 1 246 ? 223.535 199.390 196.489 1.00 7.89   ? 246 LEU D N     1 
ATOM   7270  C  CA    . LEU D 1 246 ? 222.391 199.576 195.614 1.00 7.55   ? 246 LEU D CA    1 
ATOM   7271  C  C     . LEU D 1 246 ? 221.238 198.735 196.148 1.00 6.88   ? 246 LEU D C     1 
ATOM   7272  O  O     . LEU D 1 246 ? 221.313 197.512 196.136 1.00 6.91   ? 246 LEU D O     1 
ATOM   7273  C  CB    . LEU D 1 246 ? 222.716 199.192 194.170 1.00 7.71   ? 246 LEU D CB    1 
ATOM   7274  C  CG    . LEU D 1 246 ? 223.450 200.231 193.319 1.00 7.88   ? 246 LEU D CG    1 
ATOM   7275  C  CD1   . LEU D 1 246 ? 223.934 199.617 192.030 1.00 7.79   ? 246 LEU D CD1   1 
ATOM   7276  C  CD2   . LEU D 1 246 ? 222.575 201.450 193.024 1.00 8.02   ? 246 LEU D CD2   1 
ATOM   7277  N  N     . ASN D 1 247 ? 220.155 199.386 196.566 1.00 6.42   ? 247 ASN D N     1 
ATOM   7278  C  CA    . ASN D 1 247 ? 219.019 198.673 197.109 1.00 6.30   ? 247 ASN D CA    1 
ATOM   7279  C  C     . ASN D 1 247 ? 217.752 199.511 196.957 1.00 6.35   ? 247 ASN D C     1 
ATOM   7280  O  O     . ASN D 1 247 ? 217.775 200.727 197.111 1.00 6.11   ? 247 ASN D O     1 
ATOM   7281  C  CB    . ASN D 1 247 ? 219.265 198.326 198.567 1.00 6.21   ? 247 ASN D CB    1 
ATOM   7282  C  CG    . ASN D 1 247 ? 218.381 197.206 199.057 1.00 6.09   ? 247 ASN D CG    1 
ATOM   7283  O  OD1   . ASN D 1 247 ? 217.694 196.548 198.270 1.00 5.96   ? 247 ASN D OD1   1 
ATOM   7284  N  ND2   . ASN D 1 247 ? 218.407 196.960 200.357 1.00 6.16   ? 247 ASN D ND2   1 
ATOM   7285  N  N     . GLY D 1 248 ? 216.644 198.835 196.645 1.00 6.31   ? 248 GLY D N     1 
ATOM   7286  C  CA    . GLY D 1 248 ? 215.339 199.465 196.642 1.00 6.59   ? 248 GLY D CA    1 
ATOM   7287  C  C     . GLY D 1 248 ? 215.173 200.525 195.570 1.00 7.01   ? 248 GLY D C     1 
ATOM   7288  O  O     . GLY D 1 248 ? 214.366 201.421 195.754 1.00 7.02   ? 248 GLY D O     1 
ATOM   7289  N  N     . GLU D 1 249 ? 215.889 200.403 194.448 1.00 7.66   ? 249 GLU D N     1 
ATOM   7290  C  CA    . GLU D 1 249 ? 215.929 201.451 193.445 1.00 8.77   ? 249 GLU D CA    1 
ATOM   7291  C  C     . GLU D 1 249 ? 215.631 200.863 192.071 1.00 8.50   ? 249 GLU D C     1 
ATOM   7292  O  O     . GLU D 1 249 ? 215.916 199.712 191.812 1.00 8.59   ? 249 GLU D O     1 
ATOM   7293  C  CB    . GLU D 1 249 ? 217.304 202.150 193.487 1.00 10.24  ? 249 GLU D CB    1 
ATOM   7294  C  CG    . GLU D 1 249 ? 217.712 202.947 192.251 1.00 11.92  ? 249 GLU D CG    1 
ATOM   7295  C  CD    . GLU D 1 249 ? 216.883 204.212 191.999 1.00 13.92  ? 249 GLU D CD    1 
ATOM   7296  O  OE1   . GLU D 1 249 ? 215.796 204.398 192.612 1.00 15.65  ? 249 GLU D OE1   1 
ATOM   7297  O  OE2   . GLU D 1 249 ? 217.328 205.026 191.148 1.00 13.48  ? 249 GLU D OE2   1 
ATOM   7298  N  N     . VAL D 1 250 ? 215.069 201.700 191.204 1.00 8.62   ? 250 VAL D N     1 
ATOM   7299  C  CA    . VAL D 1 250 ? 214.840 201.374 189.810 1.00 9.54   ? 250 VAL D CA    1 
ATOM   7300  C  C     . VAL D 1 250 ? 215.840 202.147 188.966 1.00 9.45   ? 250 VAL D C     1 
ATOM   7301  O  O     . VAL D 1 250 ? 215.918 203.365 189.077 1.00 10.40  ? 250 VAL D O     1 
ATOM   7302  C  CB    . VAL D 1 250 ? 213.406 201.716 189.383 1.00 10.00  ? 250 VAL D CB    1 
ATOM   7303  C  CG1   . VAL D 1 250 ? 213.177 201.327 187.936 1.00 10.69  ? 250 VAL D CG1   1 
ATOM   7304  C  CG2   . VAL D 1 250 ? 212.388 201.018 190.263 1.00 10.72  ? 250 VAL D CG2   1 
ATOM   7305  N  N     . ILE D 1 251 ? 216.597 201.433 188.133 1.00 9.01   ? 251 ILE D N     1 
ATOM   7306  C  CA    . ILE D 1 251 ? 217.555 202.051 187.239 1.00 9.13   ? 251 ILE D CA    1 
ATOM   7307  C  C     . ILE D 1 251 ? 217.035 201.972 185.810 1.00 9.48   ? 251 ILE D C     1 
ATOM   7308  O  O     . ILE D 1 251 ? 216.853 200.877 185.286 1.00 10.10  ? 251 ILE D O     1 
ATOM   7309  C  CB    . ILE D 1 251 ? 218.935 201.387 187.361 1.00 8.85   ? 251 ILE D CB    1 
ATOM   7310  C  CG1   . ILE D 1 251 ? 219.495 201.547 188.761 1.00 8.97   ? 251 ILE D CG1   1 
ATOM   7311  C  CG2   . ILE D 1 251 ? 219.894 201.960 186.314 1.00 8.89   ? 251 ILE D CG2   1 
ATOM   7312  C  CD1   . ILE D 1 251 ? 220.751 200.742 189.012 1.00 9.05   ? 251 ILE D CD1   1 
ATOM   7313  N  N     . ARG D 1 252 ? 216.818 203.131 185.190 1.00 9.93   ? 252 ARG D N     1 
ATOM   7314  C  CA    . ARG D 1 252 ? 216.431 203.188 183.795 1.00 10.76  ? 252 ARG D CA    1 
ATOM   7315  C  C     . ARG D 1 252 ? 217.655 202.955 182.910 1.00 10.03  ? 252 ARG D C     1 
ATOM   7316  O  O     . ARG D 1 252 ? 218.644 203.673 183.005 1.00 10.35  ? 252 ARG D O     1 
ATOM   7317  C  CB    . ARG D 1 252 ? 215.788 204.529 183.446 1.00 12.43  ? 252 ARG D CB    1 
ATOM   7318  C  CG    . ARG D 1 252 ? 214.468 204.785 184.151 1.00 15.00  ? 252 ARG D CG    1 
ATOM   7319  C  CD    . ARG D 1 252 ? 213.964 206.174 183.828 1.00 17.34  ? 252 ARG D CD    1 
ATOM   7320  N  NE    . ARG D 1 252 ? 213.701 206.329 182.394 1.00 18.95  ? 252 ARG D NE    1 
ATOM   7321  C  CZ    . ARG D 1 252 ? 212.539 206.720 181.862 1.00 21.94  ? 252 ARG D CZ    1 
ATOM   7322  N  NH1   . ARG D 1 252 ? 211.518 207.059 182.634 1.00 22.32  ? 252 ARG D NH1   1 
ATOM   7323  N  NH2   . ARG D 1 252 ? 212.398 206.762 180.547 1.00 20.84  ? 252 ARG D NH2   1 
ATOM   7324  N  N     . LEU D 1 253 ? 217.564 201.950 182.049 1.00 9.95   ? 253 LEU D N     1 
ATOM   7325  C  CA    . LEU D 1 253 ? 218.609 201.634 181.096 1.00 10.27  ? 253 LEU D CA    1 
ATOM   7326  C  C     . LEU D 1 253 ? 218.015 201.799 179.705 1.00 10.66  ? 253 LEU D C     1 
ATOM   7327  O  O     . LEU D 1 253 ? 217.501 200.833 179.127 1.00 11.21  ? 253 LEU D O     1 
ATOM   7328  C  CB    . LEU D 1 253 ? 219.103 200.205 181.345 1.00 10.60  ? 253 LEU D CB    1 
ATOM   7329  C  CG    . LEU D 1 253 ? 220.277 199.710 180.497 1.00 10.44  ? 253 LEU D CG    1 
ATOM   7330  C  CD1   . LEU D 1 253 ? 221.534 200.519 180.737 1.00 10.37  ? 253 LEU D CD1   1 
ATOM   7331  C  CD2   . LEU D 1 253 ? 220.536 198.257 180.817 1.00 10.96  ? 253 LEU D CD2   1 
ATOM   7332  N  N     . ASP D 1 254 ? 218.057 203.037 179.191 1.00 10.94  ? 254 ASP D N     1 
ATOM   7333  C  CA    . ASP D 1 254 ? 217.243 203.361 178.029 1.00 11.59  ? 254 ASP D CA    1 
ATOM   7334  C  C     . ASP D 1 254 ? 217.904 204.319 177.044 1.00 11.62  ? 254 ASP D C     1 
ATOM   7335  O  O     . ASP D 1 254 ? 217.251 204.750 176.097 1.00 12.02  ? 254 ASP D O     1 
ATOM   7336  C  CB    . ASP D 1 254 ? 215.910 203.929 178.475 1.00 12.43  ? 254 ASP D CB    1 
ATOM   7337  C  CG    . ASP D 1 254 ? 216.016 205.118 179.414 1.00 13.48  ? 254 ASP D CG    1 
ATOM   7338  O  OD1   . ASP D 1 254 ? 217.097 205.743 179.457 1.00 14.35  ? 254 ASP D OD1   1 
ATOM   7339  O  OD2   . ASP D 1 254 ? 215.024 205.377 180.127 1.00 14.75  ? 254 ASP D OD2   1 
ATOM   7340  N  N     . GLY D 1 255 ? 219.179 204.665 177.240 1.00 12.58  ? 255 GLY D N     1 
ATOM   7341  C  CA    . GLY D 1 255 ? 219.850 205.633 176.379 1.00 12.85  ? 255 GLY D CA    1 
ATOM   7342  C  C     . GLY D 1 255 ? 219.165 207.003 176.370 1.00 12.98  ? 255 GLY D C     1 
ATOM   7343  O  O     . GLY D 1 255 ? 219.203 207.703 175.367 1.00 13.60  ? 255 GLY D O     1 
ATOM   7344  N  N     . ALA D 1 256 ? 218.520 207.374 177.487 1.00 13.83  ? 256 ALA D N     1 
ATOM   7345  C  CA    . ALA D 1 256 ? 217.885 208.675 177.673 1.00 13.95  ? 256 ALA D CA    1 
ATOM   7346  C  C     . ALA D 1 256 ? 216.622 208.851 176.838 1.00 15.66  ? 256 ALA D C     1 
ATOM   7347  O  O     . ALA D 1 256 ? 216.220 209.982 176.579 1.00 17.57  ? 256 ALA D O     1 
ATOM   7348  C  CB    . ALA D 1 256 ? 218.863 209.803 177.414 1.00 13.46  ? 256 ALA D CB    1 
ATOM   7349  N  N     . ILE D 1 257 ? 215.975 207.762 176.429 1.00 18.40  ? 257 ILE D N     1 
ATOM   7350  C  CA    . ILE D 1 257 ? 214.743 207.885 175.663 1.00 19.40  ? 257 ILE D CA    1 
ATOM   7351  C  C     . ILE D 1 257 ? 213.571 208.171 176.603 1.00 20.99  ? 257 ILE D C     1 
ATOM   7352  O  O     . ILE D 1 257 ? 213.556 207.723 177.752 1.00 22.94  ? 257 ILE D O     1 
ATOM   7353  C  CB    . ILE D 1 257 ? 214.481 206.627 174.820 1.00 20.60  ? 257 ILE D CB    1 
ATOM   7354  C  CG1   . ILE D 1 257 ? 213.503 206.944 173.694 1.00 21.95  ? 257 ILE D CG1   1 
ATOM   7355  C  CG2   . ILE D 1 257 ? 214.017 205.456 175.700 1.00 20.73  ? 257 ILE D CG2   1 
ATOM   7356  C  CD1   . ILE D 1 257 ? 213.378 205.826 172.670 1.00 24.19  ? 257 ILE D CD1   1 
ATOM   7357  N  N     . ARG D 1 258 ? 212.599 208.932 176.097 1.00 21.52  ? 258 ARG D N     1 
ATOM   7358  C  CA    . ARG D 1 258 ? 211.318 209.115 176.751 1.00 24.04  ? 258 ARG D CA    1 
ATOM   7359  C  C     . ARG D 1 258 ? 210.232 208.828 175.721 1.00 25.38  ? 258 ARG D C     1 
ATOM   7360  O  O     . ARG D 1 258 ? 210.098 209.553 174.744 1.00 26.89  ? 258 ARG D O     1 
ATOM   7361  C  CB    . ARG D 1 258 ? 211.159 210.519 177.342 1.00 24.20  ? 258 ARG D CB    1 
ATOM   7362  C  CG    . ARG D 1 258 ? 212.205 210.873 178.387 1.00 25.09  ? 258 ARG D CG    1 
ATOM   7363  C  CD    . ARG D 1 258 ? 212.055 209.990 179.615 1.00 26.04  ? 258 ARG D CD    1 
ATOM   7364  N  NE    . ARG D 1 258 ? 213.002 210.389 180.661 1.00 25.27  ? 258 ARG D NE    1 
ATOM   7365  C  CZ    . ARG D 1 258 ? 214.217 209.880 180.828 1.00 24.52  ? 258 ARG D CZ    1 
ATOM   7366  N  NH1   . ARG D 1 258 ? 214.706 208.975 179.989 1.00 23.05  ? 258 ARG D NH1   1 
ATOM   7367  N  NH2   . ARG D 1 258 ? 214.945 210.293 181.854 1.00 24.75  ? 258 ARG D NH2   1 
ATOM   7368  N  N     . MET D 1 259 ? 209.453 207.777 175.959 1.00 28.20  ? 259 MET D N     1 
ATOM   7369  C  CA    . MET D 1 259 ? 208.547 207.258 174.946 1.00 30.92  ? 259 MET D CA    1 
ATOM   7370  C  C     . MET D 1 259 ? 207.381 208.220 174.719 1.00 32.25  ? 259 MET D C     1 
ATOM   7371  O  O     . MET D 1 259 ? 206.811 208.760 175.667 1.00 32.31  ? 259 MET D O     1 
ATOM   7372  C  CB    . MET D 1 259 ? 208.001 205.888 175.356 1.00 32.27  ? 259 MET D CB    1 
ATOM   7373  C  CG    . MET D 1 259 ? 209.066 204.886 175.749 1.00 34.51  ? 259 MET D CG    1 
ATOM   7374  S  SD    . MET D 1 259 ? 210.195 204.546 174.386 1.00 39.79  ? 259 MET D SD    1 
ATOM   7375  C  CE    . MET D 1 259 ? 209.320 203.268 173.480 1.00 40.32  ? 259 MET D CE    1 
ATOM   7376  N  N     . GLN D 1 260 ? 207.090 208.464 173.435 1.00 35.18  ? 260 GLN D N     1 
ATOM   7377  C  CA    . GLN D 1 260 ? 205.956 209.270 173.018 1.00 37.48  ? 260 GLN D CA    1 
ATOM   7378  C  C     . GLN D 1 260 ? 204.730 208.381 172.824 1.00 35.59  ? 260 GLN D C     1 
ATOM   7379  O  O     . GLN D 1 260 ? 204.861 207.162 172.713 1.00 36.03  ? 260 GLN D O     1 
ATOM   7380  C  CB    . GLN D 1 260 ? 206.305 210.009 171.725 1.00 42.80  ? 260 GLN D CB    1 
ATOM   7381  C  CG    . GLN D 1 260 ? 207.252 211.184 171.939 1.00 48.85  ? 260 GLN D CG    1 
ATOM   7382  C  CD    . GLN D 1 260 ? 206.932 211.964 173.198 1.00 54.77  ? 260 GLN D CD    1 
ATOM   7383  O  OE1   . GLN D 1 260 ? 205.844 212.536 173.334 1.00 52.67  ? 260 GLN D OE1   1 
ATOM   7384  N  NE2   . GLN D 1 260 ? 207.856 211.943 174.152 1.00 55.55  ? 260 GLN D NE2   1 
ATOM   7385  N  N     . PRO D 1 261 ? 203.507 208.952 172.771 1.00 35.94  ? 261 PRO D N     1 
ATOM   7386  C  CA    . PRO D 1 261 ? 202.304 208.142 172.563 1.00 38.77  ? 261 PRO D CA    1 
ATOM   7387  C  C     . PRO D 1 261 ? 202.352 207.255 171.314 1.00 45.59  ? 261 PRO D C     1 
ATOM   7388  O  O     . PRO D 1 261 ? 202.806 207.751 170.252 1.00 48.63  ? 261 PRO D O     1 
ATOM   7389  C  CB    . PRO D 1 261 ? 201.178 209.179 172.456 1.00 37.53  ? 261 PRO D CB    1 
ATOM   7390  C  CG    . PRO D 1 261 ? 201.706 210.399 173.167 1.00 37.81  ? 261 PRO D CG    1 
ATOM   7391  C  CD    . PRO D 1 261 ? 203.206 210.382 172.982 1.00 37.07  ? 261 PRO D CD    1 
ATOM   7392  O  OXT   . PRO D 1 261 ? 201.943 206.081 171.431 1.00 44.64  ? 261 PRO D OXT   1 
ATOM   7393  N  N     . ALA E 2 23  ? 233.039 188.819 256.813 1.00 249.76 ? 92  ALA F N     1 
ATOM   7394  C  CA    . ALA E 2 23  ? 233.316 189.639 258.018 1.00 250.88 ? 92  ALA F CA    1 
ATOM   7395  C  C     . ALA E 2 23  ? 232.436 189.177 259.178 1.00 254.49 ? 92  ALA F C     1 
ATOM   7396  O  O     . ALA E 2 23  ? 231.796 188.131 259.107 1.00 254.70 ? 92  ALA F O     1 
ATOM   7397  C  CB    . ALA E 2 23  ? 233.115 191.109 257.699 1.00 248.33 ? 92  ALA F CB    1 
ATOM   7398  N  N     . ALA E 2 24  ? 232.430 189.957 260.263 1.00 256.45 ? 93  ALA F N     1 
ATOM   7399  C  CA    . ALA E 2 24  ? 231.579 189.673 261.408 1.00 256.35 ? 93  ALA F CA    1 
ATOM   7400  C  C     . ALA E 2 24  ? 230.123 190.038 261.117 1.00 252.99 ? 93  ALA F C     1 
ATOM   7401  O  O     . ALA E 2 24  ? 229.215 189.520 261.768 1.00 251.32 ? 93  ALA F O     1 
ATOM   7402  C  CB    . ALA E 2 24  ? 232.091 190.410 262.626 1.00 257.28 ? 93  ALA F CB    1 
ATOM   7403  N  N     . THR E 2 25  ? 229.896 190.937 260.149 1.00 250.47 ? 94  THR F N     1 
ATOM   7404  C  CA    . THR E 2 25  ? 228.556 191.422 259.850 1.00 247.02 ? 94  THR F CA    1 
ATOM   7405  C  C     . THR E 2 25  ? 227.653 190.281 259.376 1.00 248.40 ? 94  THR F C     1 
ATOM   7406  O  O     . THR E 2 25  ? 226.447 190.309 259.622 1.00 245.72 ? 94  THR F O     1 
ATOM   7407  C  CB    . THR E 2 25  ? 228.623 192.541 258.811 1.00 243.48 ? 94  THR F CB    1 
ATOM   7408  O  OG1   . THR E 2 25  ? 229.350 193.627 259.382 1.00 243.32 ? 94  THR F OG1   1 
ATOM   7409  C  CG2   . THR E 2 25  ? 227.240 193.034 258.425 1.00 239.67 ? 94  THR F CG2   1 
ATOM   7410  N  N     . ARG E 2 26  ? 228.235 189.275 258.720 1.00 252.21 ? 95  ARG F N     1 
ATOM   7411  C  CA    . ARG E 2 26  ? 227.463 188.154 258.200 1.00 255.20 ? 95  ARG F CA    1 
ATOM   7412  C  C     . ARG E 2 26  ? 226.748 187.426 259.341 1.00 259.10 ? 95  ARG F C     1 
ATOM   7413  O  O     . ARG E 2 26  ? 225.579 187.067 259.215 1.00 257.06 ? 95  ARG F O     1 
ATOM   7414  C  CB    . ARG E 2 26  ? 228.358 187.176 257.433 1.00 254.40 ? 95  ARG F CB    1 
ATOM   7415  C  CG    . ARG E 2 26  ? 229.605 187.801 256.824 1.00 252.97 ? 95  ARG F CG    1 
ATOM   7416  C  CD    . ARG E 2 26  ? 229.297 188.785 255.711 1.00 252.08 ? 95  ARG F CD    1 
ATOM   7417  N  NE    . ARG E 2 26  ? 230.522 189.231 255.039 1.00 250.42 ? 95  ARG F NE    1 
ATOM   7418  C  CZ    . ARG E 2 26  ? 230.572 190.039 253.983 1.00 248.15 ? 95  ARG F CZ    1 
ATOM   7419  N  NH1   . ARG E 2 26  ? 229.464 190.403 253.357 1.00 246.33 ? 95  ARG F NH1   1 
ATOM   7420  N  NH2   . ARG E 2 26  ? 231.740 190.456 253.527 1.00 248.21 ? 95  ARG F NH2   1 
ATOM   7421  N  N     . GLU E 2 27  ? 227.453 187.197 260.457 1.00 265.29 ? 96  GLU F N     1 
ATOM   7422  C  CA    . GLU E 2 27  ? 226.848 186.605 261.642 1.00 270.21 ? 96  GLU F CA    1 
ATOM   7423  C  C     . GLU E 2 27  ? 226.046 187.647 262.421 1.00 264.44 ? 96  GLU F C     1 
ATOM   7424  O  O     . GLU E 2 27  ? 225.045 187.304 263.048 1.00 262.13 ? 96  GLU F O     1 
ATOM   7425  C  CB    . GLU E 2 27  ? 227.921 185.967 262.523 1.00 277.79 ? 96  GLU F CB    1 
ATOM   7426  C  CG    . GLU E 2 27  ? 227.363 185.158 263.691 1.00 282.88 ? 96  GLU F CG    1 
ATOM   7427  C  CD    . GLU E 2 27  ? 227.056 185.962 264.942 1.00 286.36 ? 96  GLU F CD    1 
ATOM   7428  O  OE1   . GLU E 2 27  ? 227.666 187.033 265.138 1.00 286.60 ? 96  GLU F OE1   1 
ATOM   7429  O  OE2   . GLU E 2 27  ? 226.179 185.519 265.710 1.00 287.82 ? 96  GLU F OE2   1 
ATOM   7430  N  N     . PHE E 2 28  ? 226.484 188.911 262.393 1.00 259.85 ? 97  PHE F N     1 
ATOM   7431  C  CA    . PHE E 2 28  ? 225.854 189.957 263.187 1.00 258.25 ? 97  PHE F CA    1 
ATOM   7432  C  C     . PHE E 2 28  ? 224.397 190.176 262.778 1.00 247.83 ? 97  PHE F C     1 
ATOM   7433  O  O     . PHE E 2 28  ? 223.549 190.396 263.638 1.00 244.52 ? 97  PHE F O     1 
ATOM   7434  C  CB    . PHE E 2 28  ? 226.652 191.254 263.065 1.00 265.92 ? 97  PHE F CB    1 
ATOM   7435  C  CG    . PHE E 2 28  ? 226.095 192.394 263.896 1.00 275.65 ? 97  PHE F CG    1 
ATOM   7436  C  CD1   . PHE E 2 28  ? 226.239 192.397 265.278 1.00 281.00 ? 97  PHE F CD1   1 
ATOM   7437  C  CD2   . PHE E 2 28  ? 225.440 193.461 263.293 1.00 277.56 ? 97  PHE F CD2   1 
ATOM   7438  C  CE1   . PHE E 2 28  ? 225.740 193.444 266.037 1.00 282.70 ? 97  PHE F CE1   1 
ATOM   7439  C  CE2   . PHE E 2 28  ? 224.949 194.508 264.055 1.00 279.15 ? 97  PHE F CE2   1 
ATOM   7440  C  CZ    . PHE E 2 28  ? 225.096 194.497 265.425 1.00 281.73 ? 97  PHE F CZ    1 
ATOM   7441  N  N     . ILE E 2 29  ? 224.111 190.132 261.473 1.00 239.63 ? 98  ILE F N     1 
ATOM   7442  C  CA    . ILE E 2 29  ? 222.756 190.329 260.977 1.00 233.73 ? 98  ILE F CA    1 
ATOM   7443  C  C     . ILE E 2 29  ? 221.835 189.177 261.390 1.00 232.19 ? 98  ILE F C     1 
ATOM   7444  O  O     . ILE E 2 29  ? 220.619 189.352 261.452 1.00 226.25 ? 98  ILE F O     1 
ATOM   7445  C  CB    . ILE E 2 29  ? 222.766 190.515 259.448 1.00 230.92 ? 98  ILE F CB    1 
ATOM   7446  C  CG1   . ILE E 2 29  ? 221.377 190.769 258.894 1.00 225.08 ? 98  ILE F CG1   1 
ATOM   7447  C  CG2   . ILE E 2 29  ? 223.405 189.324 258.741 1.00 233.40 ? 98  ILE F CG2   1 
ATOM   7448  C  CD1   . ILE E 2 29  ? 220.717 192.023 259.424 1.00 223.81 ? 98  ILE F CD1   1 
ATOM   7449  N  N     . GLU E 2 30  ? 222.401 187.993 261.656 1.00 235.06 ? 99  GLU F N     1 
ATOM   7450  C  CA    . GLU E 2 30  ? 221.596 186.805 261.920 1.00 237.90 ? 99  GLU F CA    1 
ATOM   7451  C  C     . GLU E 2 30  ? 220.695 186.996 263.143 1.00 230.58 ? 99  GLU F C     1 
ATOM   7452  O  O     . GLU E 2 30  ? 219.530 186.598 263.126 1.00 227.52 ? 99  GLU F O     1 
ATOM   7453  C  CB    . GLU E 2 30  ? 222.486 185.574 262.100 1.00 246.11 ? 99  GLU F CB    1 
ATOM   7454  C  CG    . GLU E 2 30  ? 223.270 185.204 260.845 1.00 252.53 ? 99  GLU F CG    1 
ATOM   7455  C  CD    . GLU E 2 30  ? 222.439 185.256 259.578 1.00 256.45 ? 99  GLU F CD    1 
ATOM   7456  O  OE1   . GLU E 2 30  ? 221.437 184.516 259.494 1.00 257.44 ? 99  GLU F OE1   1 
ATOM   7457  O  OE2   . GLU E 2 30  ? 222.782 186.059 258.689 1.00 257.21 ? 99  GLU F OE2   1 
ATOM   7458  N  N     . MET E 2 31  ? 221.236 187.600 264.205 1.00 226.04 ? 100 MET F N     1 
ATOM   7459  C  CA    . MET E 2 31  ? 220.485 187.813 265.434 1.00 223.64 ? 100 MET F CA    1 
ATOM   7460  C  C     . MET E 2 31  ? 219.364 188.836 265.230 1.00 215.51 ? 100 MET F C     1 
ATOM   7461  O  O     . MET E 2 31  ? 218.327 188.750 265.885 1.00 210.56 ? 100 MET F O     1 
ATOM   7462  C  CB    . MET E 2 31  ? 221.422 188.256 266.564 1.00 228.96 ? 100 MET F CB    1 
ATOM   7463  C  CG    . MET E 2 31  ? 220.752 188.407 267.925 1.00 232.95 ? 100 MET F CG    1 
ATOM   7464  S  SD    . MET E 2 31  ? 220.001 190.024 268.209 1.00 236.02 ? 100 MET F SD    1 
ATOM   7465  C  CE    . MET E 2 31  ? 221.447 191.080 268.378 1.00 236.33 ? 100 MET F CE    1 
ATOM   7466  N  N     . TRP E 2 32  ? 219.569 189.807 264.331 1.00 212.71 ? 101 TRP F N     1 
ATOM   7467  C  CA    . TRP E 2 32  ? 218.561 190.824 264.066 1.00 209.39 ? 101 TRP F CA    1 
ATOM   7468  C  C     . TRP E 2 32  ? 217.286 190.203 263.500 1.00 203.58 ? 101 TRP F C     1 
ATOM   7469  O  O     . TRP E 2 32  ? 216.187 190.684 263.775 1.00 198.15 ? 101 TRP F O     1 
ATOM   7470  C  CB    . TRP E 2 32  ? 219.118 191.886 263.113 1.00 212.12 ? 101 TRP F CB    1 
ATOM   7471  C  CG    . TRP E 2 32  ? 220.145 192.774 263.757 1.00 214.13 ? 101 TRP F CG    1 
ATOM   7472  C  CD1   . TRP E 2 32  ? 221.416 192.439 264.112 1.00 217.05 ? 101 TRP F CD1   1 
ATOM   7473  C  CD2   . TRP E 2 32  ? 219.974 194.158 264.121 1.00 213.23 ? 101 TRP F CD2   1 
ATOM   7474  N  NE1   . TRP E 2 32  ? 222.048 193.511 264.680 1.00 218.07 ? 101 TRP F NE1   1 
ATOM   7475  C  CE2   . TRP E 2 32  ? 221.191 194.580 264.697 1.00 216.77 ? 101 TRP F CE2   1 
ATOM   7476  C  CE3   . TRP E 2 32  ? 218.922 195.073 264.014 1.00 210.64 ? 101 TRP F CE3   1 
ATOM   7477  C  CZ2   . TRP E 2 32  ? 221.377 195.879 265.166 1.00 216.54 ? 101 TRP F CZ2   1 
ATOM   7478  C  CZ3   . TRP E 2 32  ? 219.105 196.354 264.484 1.00 211.42 ? 101 TRP F CZ3   1 
ATOM   7479  C  CH2   . TRP E 2 32  ? 220.318 196.749 265.048 1.00 214.02 ? 101 TRP F CH2   1 
ATOM   7480  N  N     . ARG E 2 33  ? 217.434 189.128 262.717 1.00 201.62 ? 102 ARG F N     1 
ATOM   7481  C  CA    . ARG E 2 33  ? 216.285 188.446 262.139 1.00 198.77 ? 102 ARG F CA    1 
ATOM   7482  C  C     . ARG E 2 33  ? 215.407 187.837 263.232 1.00 201.20 ? 102 ARG F C     1 
ATOM   7483  O  O     . ARG E 2 33  ? 214.180 187.911 263.155 1.00 197.94 ? 102 ARG F O     1 
ATOM   7484  C  CB    . ARG E 2 33  ? 216.741 187.381 261.138 1.00 195.51 ? 102 ARG F CB    1 
ATOM   7485  C  CG    . ARG E 2 33  ? 215.622 186.873 260.238 1.00 191.81 ? 102 ARG F CG    1 
ATOM   7486  C  CD    . ARG E 2 33  ? 216.114 186.029 259.077 1.00 190.28 ? 102 ARG F CD    1 
ATOM   7487  N  NE    . ARG E 2 33  ? 216.531 186.843 257.928 1.00 188.48 ? 102 ARG F NE    1 
ATOM   7488  C  CZ    . ARG E 2 33  ? 217.745 186.893 257.388 1.00 188.38 ? 102 ARG F CZ    1 
ATOM   7489  N  NH1   . ARG E 2 33  ? 218.756 186.204 257.893 1.00 188.58 ? 102 ARG F NH1   1 
ATOM   7490  N  NH2   . ARG E 2 33  ? 217.953 187.649 256.325 1.00 187.10 ? 102 ARG F NH2   1 
ATOM   7491  N  N     . LEU E 2 34  ? 216.034 187.258 264.260 1.00 205.46 ? 103 LEU F N     1 
ATOM   7492  C  CA    . LEU E 2 34  ? 215.298 186.579 265.319 1.00 207.90 ? 103 LEU F CA    1 
ATOM   7493  C  C     . LEU E 2 34  ? 214.410 187.548 266.101 1.00 201.82 ? 103 LEU F C     1 
ATOM   7494  O  O     . LEU E 2 34  ? 213.399 187.127 266.661 1.00 200.65 ? 103 LEU F O     1 
ATOM   7495  C  CB    . LEU E 2 34  ? 216.264 185.857 266.255 1.00 213.88 ? 103 LEU F CB    1 
ATOM   7496  C  CG    . LEU E 2 34  ? 217.260 184.906 265.585 1.00 218.82 ? 103 LEU F CG    1 
ATOM   7497  C  CD1   . LEU E 2 34  ? 218.192 184.294 266.617 1.00 219.84 ? 103 LEU F CD1   1 
ATOM   7498  C  CD2   . LEU E 2 34  ? 216.551 183.818 264.795 1.00 220.03 ? 103 LEU F CD2   1 
ATOM   7499  N  N     . LEU E 2 35  ? 214.783 188.834 266.155 1.00 197.52 ? 104 LEU F N     1 
ATOM   7500  C  CA    . LEU E 2 35  ? 213.986 189.827 266.865 1.00 193.79 ? 104 LEU F CA    1 
ATOM   7501  C  C     . LEU E 2 35  ? 212.815 190.337 266.024 1.00 187.83 ? 104 LEU F C     1 
ATOM   7502  O  O     . LEU E 2 35  ? 211.983 191.086 266.534 1.00 183.15 ? 104 LEU F O     1 
ATOM   7503  C  CB    . LEU E 2 35  ? 214.873 190.989 267.307 1.00 194.87 ? 104 LEU F CB    1 
ATOM   7504  C  CG    . LEU E 2 35  ? 216.074 190.628 268.187 1.00 195.78 ? 104 LEU F CG    1 
ATOM   7505  C  CD1   . LEU E 2 35  ? 216.689 191.885 268.786 1.00 195.78 ? 104 LEU F CD1   1 
ATOM   7506  C  CD2   . LEU E 2 35  ? 215.707 189.635 269.280 1.00 196.52 ? 104 LEU F CD2   1 
ATOM   7507  N  N     . GLY E 2 36  ? 212.745 189.951 264.745 1.00 184.15 ? 105 GLY F N     1 
ATOM   7508  C  CA    . GLY E 2 36  ? 211.645 190.360 263.884 1.00 181.25 ? 105 GLY F CA    1 
ATOM   7509  C  C     . GLY E 2 36  ? 211.661 191.863 263.617 1.00 177.60 ? 105 GLY F C     1 
ATOM   7510  O  O     . GLY E 2 36  ? 210.622 192.518 263.669 1.00 176.12 ? 105 GLY F O     1 
ATOM   7511  N  N     . ARG E 2 37  ? 212.843 192.398 263.297 1.00 173.22 ? 106 ARG F N     1 
ATOM   7512  C  CA    . ARG E 2 37  ? 212.992 193.824 263.051 1.00 171.09 ? 106 ARG F CA    1 
ATOM   7513  C  C     . ARG E 2 37  ? 212.865 194.144 261.561 1.00 166.61 ? 106 ARG F C     1 
ATOM   7514  O  O     . ARG E 2 37  ? 213.714 194.844 261.006 1.00 169.95 ? 106 ARG F O     1 
ATOM   7515  C  CB    . ARG E 2 37  ? 214.349 194.300 263.576 1.00 173.71 ? 106 ARG F CB    1 
ATOM   7516  C  CG    . ARG E 2 37  ? 214.524 194.235 265.086 1.00 175.93 ? 106 ARG F CG    1 
ATOM   7517  C  CD    . ARG E 2 37  ? 215.936 194.665 265.424 1.00 178.47 ? 106 ARG F CD    1 
ATOM   7518  N  NE    . ARG E 2 37  ? 216.229 194.578 266.857 1.00 181.60 ? 106 ARG F NE    1 
ATOM   7519  C  CZ    . ARG E 2 37  ? 216.143 195.575 267.723 1.00 182.22 ? 106 ARG F CZ    1 
ATOM   7520  N  NH1   . ARG E 2 37  ? 215.653 196.746 267.353 1.00 181.74 ? 106 ARG F NH1   1 
ATOM   7521  N  NH2   . ARG E 2 37  ? 216.528 195.388 268.973 1.00 182.58 ? 106 ARG F NH2   1 
ATOM   7522  N  N     . GLU E 2 38  ? 211.794 193.644 260.926 1.00 157.78 ? 107 GLU F N     1 
ATOM   7523  C  CA    . GLU E 2 38  ? 211.467 193.962 259.539 1.00 150.20 ? 107 GLU F CA    1 
ATOM   7524  C  C     . GLU E 2 38  ? 212.698 193.802 258.647 1.00 137.87 ? 107 GLU F C     1 
ATOM   7525  O  O     . GLU E 2 38  ? 213.161 194.758 258.022 1.00 136.94 ? 107 GLU F O     1 
ATOM   7526  C  CB    . GLU E 2 38  ? 210.889 195.375 259.432 1.00 155.07 ? 107 GLU F CB    1 
ATOM   7527  C  CG    . GLU E 2 38  ? 209.554 195.558 260.149 1.00 160.11 ? 107 GLU F CG    1 
ATOM   7528  C  CD    . GLU E 2 38  ? 208.400 194.779 259.542 1.00 162.88 ? 107 GLU F CD    1 
ATOM   7529  O  OE1   . GLU E 2 38  ? 208.372 194.669 258.300 1.00 161.29 ? 107 GLU F OE1   1 
ATOM   7530  O  OE2   . GLU E 2 38  ? 207.525 194.304 260.298 1.00 165.00 ? 107 GLU F OE2   1 
ATOM   7531  N  N     . VAL E 2 39  ? 213.197 192.564 258.582 1.00 128.66 ? 108 VAL F N     1 
ATOM   7532  C  CA    . VAL E 2 39  ? 214.448 192.252 257.913 1.00 121.91 ? 108 VAL F CA    1 
ATOM   7533  C  C     . VAL E 2 39  ? 214.142 191.297 256.766 1.00 118.05 ? 108 VAL F C     1 
ATOM   7534  O  O     . VAL E 2 39  ? 213.300 190.413 256.909 1.00 119.48 ? 108 VAL F O     1 
ATOM   7535  C  CB    . VAL E 2 39  ? 215.454 191.625 258.896 1.00 121.28 ? 108 VAL F CB    1 
ATOM   7536  C  CG1   . VAL E 2 39  ? 214.881 190.382 259.558 1.00 124.75 ? 108 VAL F CG1   1 
ATOM   7537  C  CG2   . VAL E 2 39  ? 216.783 191.291 258.232 1.00 118.27 ? 108 VAL F CG2   1 
ATOM   7538  N  N     . PRO E 2 40  ? 214.792 191.443 255.593 1.00 115.71 ? 109 PRO F N     1 
ATOM   7539  C  CA    . PRO E 2 40  ? 214.572 190.502 254.500 1.00 117.59 ? 109 PRO F CA    1 
ATOM   7540  C  C     . PRO E 2 40  ? 215.183 189.136 254.788 1.00 124.36 ? 109 PRO F C     1 
ATOM   7541  O  O     . PRO E 2 40  ? 216.134 189.018 255.557 1.00 123.55 ? 109 PRO F O     1 
ATOM   7542  C  CB    . PRO E 2 40  ? 215.231 191.186 253.303 1.00 114.23 ? 109 PRO F CB    1 
ATOM   7543  C  CG    . PRO E 2 40  ? 216.308 192.036 253.925 1.00 113.01 ? 109 PRO F CG    1 
ATOM   7544  C  CD    . PRO E 2 40  ? 215.716 192.530 255.229 1.00 114.56 ? 109 PRO F CD    1 
ATOM   7545  N  N     . GLU E 2 41  ? 214.631 188.110 254.140 1.00 132.99 ? 110 GLU F N     1 
ATOM   7546  C  CA    . GLU E 2 41  ? 215.148 186.757 254.276 1.00 139.82 ? 110 GLU F CA    1 
ATOM   7547  C  C     . GLU E 2 41  ? 216.505 186.635 253.581 1.00 141.13 ? 110 GLU F C     1 
ATOM   7548  O  O     . GLU E 2 41  ? 217.448 186.089 254.153 1.00 142.84 ? 110 GLU F O     1 
ATOM   7549  C  CB    . GLU E 2 41  ? 214.159 185.736 253.710 1.00 145.83 ? 110 GLU F CB    1 
ATOM   7550  C  CG    . GLU E 2 41  ? 213.006 185.388 254.645 1.00 152.85 ? 110 GLU F CG    1 
ATOM   7551  C  CD    . GLU E 2 41  ? 211.875 186.397 254.689 1.00 157.74 ? 110 GLU F CD    1 
ATOM   7552  O  OE1   . GLU E 2 41  ? 212.081 187.558 254.282 1.00 156.91 ? 110 GLU F OE1   1 
ATOM   7553  O  OE2   . GLU E 2 41  ? 210.776 186.000 255.115 1.00 161.49 ? 110 GLU F OE2   1 
ATOM   7554  N  N     . HIS E 2 42  ? 216.591 187.116 252.335 1.00 142.85 ? 111 HIS F N     1 
ATOM   7555  C  CA    . HIS E 2 42  ? 217.792 186.963 251.529 1.00 147.37 ? 111 HIS F CA    1 
ATOM   7556  C  C     . HIS E 2 42  ? 218.429 188.326 251.280 1.00 141.87 ? 111 HIS F C     1 
ATOM   7557  O  O     . HIS E 2 42  ? 217.761 189.249 250.816 1.00 141.50 ? 111 HIS F O     1 
ATOM   7558  C  CB    . HIS E 2 42  ? 217.476 186.276 250.197 1.00 157.06 ? 111 HIS F CB    1 
ATOM   7559  C  CG    . HIS E 2 42  ? 216.951 184.885 250.334 1.00 167.23 ? 111 HIS F CG    1 
ATOM   7560  N  ND1   . HIS E 2 42  ? 217.727 183.846 250.801 1.00 173.79 ? 111 HIS F ND1   1 
ATOM   7561  C  CD2   . HIS E 2 42  ? 215.743 184.357 250.078 1.00 172.33 ? 111 HIS F CD2   1 
ATOM   7562  C  CE1   . HIS E 2 42  ? 217.006 182.734 250.821 1.00 177.21 ? 111 HIS F CE1   1 
ATOM   7563  N  NE2   . HIS E 2 42  ? 215.797 183.020 250.386 1.00 175.57 ? 111 HIS F NE2   1 
ATOM   7564  N  N     . ILE E 2 43  ? 219.728 188.431 251.594 1.00 137.11 ? 112 ILE F N     1 
ATOM   7565  C  CA    . ILE E 2 43  ? 220.491 189.651 251.387 1.00 134.34 ? 112 ILE F CA    1 
ATOM   7566  C  C     . ILE E 2 43  ? 221.767 189.288 250.637 1.00 131.65 ? 112 ILE F C     1 
ATOM   7567  O  O     . ILE E 2 43  ? 222.598 188.542 251.150 1.00 131.58 ? 112 ILE F O     1 
ATOM   7568  C  CB    . ILE E 2 43  ? 220.804 190.355 252.720 1.00 134.49 ? 112 ILE F CB    1 
ATOM   7569  C  CG1   . ILE E 2 43  ? 219.571 190.440 253.609 1.00 136.79 ? 112 ILE F CG1   1 
ATOM   7570  C  CG2   . ILE E 2 43  ? 221.412 191.735 252.471 1.00 132.43 ? 112 ILE F CG2   1 
ATOM   7571  C  CD1   . ILE E 2 43  ? 219.857 190.897 255.025 1.00 138.66 ? 112 ILE F CD1   1 
ATOM   7572  N  N     . THR E 2 44  ? 221.923 189.841 249.430 1.00 131.27 ? 113 THR F N     1 
ATOM   7573  C  CA    . THR E 2 44  ? 223.078 189.538 248.600 1.00 133.34 ? 113 THR F CA    1 
ATOM   7574  C  C     . THR E 2 44  ? 224.327 190.197 249.177 1.00 135.99 ? 113 THR F C     1 
ATOM   7575  O  O     . THR E 2 44  ? 224.250 191.122 249.983 1.00 136.44 ? 113 THR F O     1 
ATOM   7576  C  CB    . THR E 2 44  ? 222.831 189.977 247.158 1.00 133.44 ? 113 THR F CB    1 
ATOM   7577  O  OG1   . THR E 2 44  ? 222.657 191.391 247.132 1.00 132.44 ? 113 THR F OG1   1 
ATOM   7578  C  CG2   . THR E 2 44  ? 221.610 189.300 246.564 1.00 134.56 ? 113 THR F CG2   1 
ATOM   7579  N  N     . GLU E 2 45  ? 225.490 189.709 248.738 1.00 142.96 ? 114 GLU F N     1 
ATOM   7580  C  CA    . GLU E 2 45  ? 226.766 190.171 249.263 1.00 147.80 ? 114 GLU F CA    1 
ATOM   7581  C  C     . GLU E 2 45  ? 226.968 191.659 248.978 1.00 142.89 ? 114 GLU F C     1 
ATOM   7582  O  O     . GLU E 2 45  ? 227.450 192.395 249.837 1.00 141.85 ? 114 GLU F O     1 
ATOM   7583  C  CB    . GLU E 2 45  ? 227.916 189.348 248.685 1.00 156.38 ? 114 GLU F CB    1 
ATOM   7584  C  CG    . GLU E 2 45  ? 229.269 189.710 249.290 1.00 163.98 ? 114 GLU F CG    1 
ATOM   7585  C  CD    . GLU E 2 45  ? 230.419 188.839 248.820 1.00 171.24 ? 114 GLU F CD    1 
ATOM   7586  O  OE1   . GLU E 2 45  ? 230.203 187.949 247.969 1.00 175.91 ? 114 GLU F OE1   1 
ATOM   7587  O  OE2   . GLU E 2 45  ? 231.542 189.056 249.317 1.00 173.67 ? 114 GLU F OE2   1 
ATOM   7588  N  N     . GLU E 2 46  ? 226.609 192.106 247.772 1.00 142.09 ? 115 GLU F N     1 
ATOM   7589  C  CA    . GLU E 2 46  ? 226.764 193.512 247.422 1.00 141.57 ? 115 GLU F CA    1 
ATOM   7590  C  C     . GLU E 2 46  ? 225.887 194.400 248.307 1.00 134.68 ? 115 GLU F C     1 
ATOM   7591  O  O     . GLU E 2 46  ? 226.181 195.581 248.480 1.00 132.94 ? 115 GLU F O     1 
ATOM   7592  C  CB    . GLU E 2 46  ? 226.481 193.787 245.946 1.00 147.48 ? 115 GLU F CB    1 
ATOM   7593  C  CG    . GLU E 2 46  ? 225.046 193.492 245.516 1.00 153.19 ? 115 GLU F CG    1 
ATOM   7594  C  CD    . GLU E 2 46  ? 224.802 192.052 245.106 1.00 156.59 ? 115 GLU F CD    1 
ATOM   7595  O  OE1   . GLU E 2 46  ? 225.643 191.183 245.420 1.00 156.03 ? 115 GLU F OE1   1 
ATOM   7596  O  OE2   . GLU E 2 46  ? 223.775 191.812 244.441 1.00 159.08 ? 115 GLU F OE2   1 
ATOM   7597  N  N     . GLU E 2 47  ? 224.806 193.844 248.862 1.00 129.50 ? 116 GLU F N     1 
ATOM   7598  C  CA    . GLU E 2 47  ? 223.989 194.584 249.814 1.00 125.66 ? 116 GLU F CA    1 
ATOM   7599  C  C     . GLU E 2 47  ? 224.651 194.648 251.192 1.00 125.73 ? 116 GLU F C     1 
ATOM   7600  O  O     . GLU E 2 47  ? 224.436 195.614 251.920 1.00 125.62 ? 116 GLU F O     1 
ATOM   7601  C  CB    . GLU E 2 47  ? 222.590 193.988 249.928 1.00 125.49 ? 116 GLU F CB    1 
ATOM   7602  C  CG    . GLU E 2 47  ? 221.722 194.239 248.699 1.00 127.70 ? 116 GLU F CG    1 
ATOM   7603  C  CD    . GLU E 2 47  ? 220.650 193.183 248.495 1.00 129.30 ? 116 GLU F CD    1 
ATOM   7604  O  OE1   . GLU E 2 47  ? 220.298 192.483 249.470 1.00 129.05 ? 116 GLU F OE1   1 
ATOM   7605  O  OE2   . GLU E 2 47  ? 220.190 193.036 247.344 1.00 128.90 ? 116 GLU F OE2   1 
ATOM   7606  N  N     . LEU E 2 48  ? 225.436 193.630 251.563 1.00 127.12 ? 117 LEU F N     1 
ATOM   7607  C  CA    . LEU E 2 48  ? 226.185 193.670 252.815 1.00 128.12 ? 117 LEU F CA    1 
ATOM   7608  C  C     . LEU E 2 48  ? 227.228 194.789 252.781 1.00 129.51 ? 117 LEU F C     1 
ATOM   7609  O  O     . LEU E 2 48  ? 227.480 195.435 253.799 1.00 127.71 ? 117 LEU F O     1 
ATOM   7610  C  CB    . LEU E 2 48  ? 226.847 192.326 253.119 1.00 131.40 ? 117 LEU F CB    1 
ATOM   7611  C  CG    . LEU E 2 48  ? 226.030 191.297 253.911 1.00 132.67 ? 117 LEU F CG    1 
ATOM   7612  C  CD1   . LEU E 2 48  ? 225.635 191.826 255.280 1.00 133.33 ? 117 LEU F CD1   1 
ATOM   7613  C  CD2   . LEU E 2 48  ? 224.798 190.830 253.161 1.00 132.22 ? 117 LEU F CD2   1 
ATOM   7614  N  N     . LYS E 2 49  ? 227.846 195.014 251.617 1.00 133.86 ? 118 LYS F N     1 
ATOM   7615  C  CA    . LYS E 2 49  ? 228.816 196.090 251.475 1.00 138.81 ? 118 LYS F CA    1 
ATOM   7616  C  C     . LYS E 2 49  ? 228.159 197.453 251.692 1.00 138.23 ? 118 LYS F C     1 
ATOM   7617  O  O     . LYS E 2 49  ? 228.764 198.342 252.286 1.00 141.37 ? 118 LYS F O     1 
ATOM   7618  C  CB    . LYS E 2 49  ? 229.498 196.041 250.107 1.00 145.70 ? 118 LYS F CB    1 
ATOM   7619  C  CG    . LYS E 2 49  ? 230.429 194.858 249.925 1.00 153.42 ? 118 LYS F CG    1 
ATOM   7620  C  CD    . LYS E 2 49  ? 231.251 194.938 248.645 1.00 159.56 ? 118 LYS F CD    1 
ATOM   7621  C  CE    . LYS E 2 49  ? 230.450 194.687 247.406 1.00 162.14 ? 118 LYS F CE    1 
ATOM   7622  N  NZ    . LYS E 2 49  ? 230.079 193.275 247.288 1.00 162.32 ? 118 LYS F NZ    1 
ATOM   7623  N  N     . THR E 2 50  ? 226.926 197.629 251.205 1.00 133.72 ? 119 THR F N     1 
ATOM   7624  C  CA    . THR E 2 50  ? 226.206 198.876 251.426 1.00 129.54 ? 119 THR F CA    1 
ATOM   7625  C  C     . THR E 2 50  ? 225.842 199.048 252.899 1.00 125.39 ? 119 THR F C     1 
ATOM   7626  O  O     . THR E 2 50  ? 225.687 200.174 253.365 1.00 128.00 ? 119 THR F O     1 
ATOM   7627  C  CB    . THR E 2 50  ? 224.967 198.954 250.538 1.00 130.25 ? 119 THR F CB    1 
ATOM   7628  O  OG1   . THR E 2 50  ? 224.277 197.712 250.613 1.00 131.41 ? 119 THR F OG1   1 
ATOM   7629  C  CG2   . THR E 2 50  ? 225.338 199.246 249.097 1.00 131.23 ? 119 THR F CG2   1 
ATOM   7630  N  N     . LEU E 2 51  ? 225.703 197.939 253.632 1.00 122.54 ? 120 LEU F N     1 
ATOM   7631  C  CA    . LEU E 2 51  ? 225.429 198.006 255.062 1.00 125.10 ? 120 LEU F CA    1 
ATOM   7632  C  C     . LEU E 2 51  ? 226.633 198.562 255.825 1.00 134.24 ? 120 LEU F C     1 
ATOM   7633  O  O     . LEU E 2 51  ? 226.474 199.036 256.947 1.00 135.45 ? 120 LEU F O     1 
ATOM   7634  C  CB    . LEU E 2 51  ? 225.024 196.624 255.576 1.00 122.50 ? 120 LEU F CB    1 
ATOM   7635  C  CG    . LEU E 2 51  ? 224.324 196.557 256.938 1.00 120.92 ? 120 LEU F CG    1 
ATOM   7636  C  CD1   . LEU E 2 51  ? 223.277 195.458 256.930 1.00 118.05 ? 120 LEU F CD1   1 
ATOM   7637  C  CD2   . LEU E 2 51  ? 225.303 196.310 258.075 1.00 122.92 ? 120 LEU F CD2   1 
ATOM   7638  N  N     . MET E 2 52  ? 227.833 198.505 255.234 1.00 144.61 ? 121 MET F N     1 
ATOM   7639  C  CA    . MET E 2 52  ? 229.010 199.099 255.854 1.00 153.13 ? 121 MET F CA    1 
ATOM   7640  C  C     . MET E 2 52  ? 228.869 200.619 255.949 1.00 152.98 ? 121 MET F C     1 
ATOM   7641  O  O     . MET E 2 52  ? 229.270 201.217 256.948 1.00 154.13 ? 121 MET F O     1 
ATOM   7642  C  CB    . MET E 2 52  ? 230.283 198.750 255.074 1.00 163.03 ? 121 MET F CB    1 
ATOM   7643  C  CG    . MET E 2 52  ? 230.645 197.273 255.069 1.00 170.40 ? 121 MET F CG    1 
ATOM   7644  S  SD    . MET E 2 52  ? 230.978 196.595 256.707 1.00 180.35 ? 121 MET F SD    1 
ATOM   7645  C  CE    . MET E 2 52  ? 229.417 195.817 257.140 1.00 180.38 ? 121 MET F CE    1 
ATOM   7646  N  N     . GLU E 2 53  ? 228.294 201.244 254.916 1.00 154.44 ? 122 GLU F N     1 
ATOM   7647  C  CA    . GLU E 2 53  ? 228.135 202.691 254.900 1.00 158.58 ? 122 GLU F CA    1 
ATOM   7648  C  C     . GLU E 2 53  ? 227.207 203.156 256.026 1.00 150.96 ? 122 GLU F C     1 
ATOM   7649  O  O     . GLU E 2 53  ? 227.330 204.283 256.500 1.00 153.74 ? 122 GLU F O     1 
ATOM   7650  C  CB    . GLU E 2 53  ? 227.595 203.155 253.549 1.00 167.38 ? 122 GLU F CB    1 
ATOM   7651  C  CG    . GLU E 2 53  ? 228.477 202.749 252.372 1.00 172.94 ? 122 GLU F CG    1 
ATOM   7652  C  CD    . GLU E 2 53  ? 227.680 202.417 251.125 1.00 178.29 ? 122 GLU F CD    1 
ATOM   7653  O  OE1   . GLU E 2 53  ? 226.435 202.524 251.172 1.00 179.96 ? 122 GLU F OE1   1 
ATOM   7654  O  OE2   . GLU E 2 53  ? 228.298 202.040 250.108 1.00 180.89 ? 122 GLU F OE2   1 
ATOM   7655  N  N     . CYS E 2 54  ? 226.265 202.298 256.438 1.00 139.96 ? 123 CYS F N     1 
ATOM   7656  C  CA    . CYS E 2 54  ? 225.339 202.627 257.510 1.00 134.27 ? 123 CYS F CA    1 
ATOM   7657  C  C     . CYS E 2 54  ? 226.096 202.618 258.837 1.00 129.69 ? 123 CYS F C     1 
ATOM   7658  O  O     . CYS E 2 54  ? 226.352 201.556 259.395 1.00 129.09 ? 123 CYS F O     1 
ATOM   7659  C  CB    . CYS E 2 54  ? 224.165 201.654 257.533 1.00 131.00 ? 123 CYS F CB    1 
ATOM   7660  S  SG    . CYS E 2 54  ? 223.218 201.619 255.987 1.00 126.34 ? 123 CYS F SG    1 
ATOM   7661  N  N     . VAL E 2 55  ? 226.433 203.807 259.345 1.00 126.26 ? 124 VAL F N     1 
ATOM   7662  C  CA    . VAL E 2 55  ? 227.281 203.923 260.526 1.00 123.33 ? 124 VAL F CA    1 
ATOM   7663  C  C     . VAL E 2 55  ? 226.472 204.003 261.821 1.00 116.87 ? 124 VAL F C     1 
ATOM   7664  O  O     . VAL E 2 55  ? 227.062 204.170 262.888 1.00 119.68 ? 124 VAL F O     1 
ATOM   7665  C  CB    . VAL E 2 55  ? 228.200 205.153 260.426 1.00 127.65 ? 124 VAL F CB    1 
ATOM   7666  C  CG1   . VAL E 2 55  ? 229.074 205.093 259.184 1.00 129.23 ? 124 VAL F CG1   1 
ATOM   7667  C  CG2   . VAL E 2 55  ? 227.417 206.462 260.481 1.00 131.05 ? 124 VAL F CG2   1 
ATOM   7668  N  N     . SER E 2 56  ? 225.137 203.919 261.738 1.00 107.81 ? 125 SER F N     1 
ATOM   7669  C  CA    . SER E 2 56  ? 224.288 204.045 262.914 1.00 102.31 ? 125 SER F CA    1 
ATOM   7670  C  C     . SER E 2 56  ? 223.215 202.960 262.913 1.00 97.67  ? 125 SER F C     1 
ATOM   7671  O  O     . SER E 2 56  ? 222.896 202.383 261.876 1.00 96.59  ? 125 SER F O     1 
ATOM   7672  C  CB    . SER E 2 56  ? 223.671 205.423 262.986 1.00 103.21 ? 125 SER F CB    1 
ATOM   7673  O  OG    . SER E 2 56  ? 222.491 205.512 262.198 1.00 101.19 ? 125 SER F OG    1 
ATOM   7674  N  N     . ASN E 2 57  ? 222.645 202.712 264.095 1.00 98.15  ? 126 ASN F N     1 
ATOM   7675  C  CA    . ASN E 2 57  ? 221.575 201.741 264.249 1.00 97.92  ? 126 ASN F CA    1 
ATOM   7676  C  C     . ASN E 2 57  ? 220.367 202.156 263.411 1.00 92.66  ? 126 ASN F C     1 
ATOM   7677  O  O     . ASN E 2 57  ? 219.748 201.324 262.749 1.00 92.50  ? 126 ASN F O     1 
ATOM   7678  C  CB    . ASN E 2 57  ? 221.198 201.570 265.717 1.00 106.55 ? 126 ASN F CB    1 
ATOM   7679  C  CG    . ASN E 2 57  ? 220.302 200.376 265.957 1.00 116.38 ? 126 ASN F CG    1 
ATOM   7680  O  OD1   . ASN E 2 57  ? 219.202 200.295 265.398 1.00 121.00 ? 126 ASN F OD1   1 
ATOM   7681  N  ND2   . ASN E 2 57  ? 220.744 199.441 266.788 1.00 120.78 ? 126 ASN F ND2   1 
ATOM   7682  N  N     . THR E 2 58  ? 220.022 203.449 263.452 1.00 89.48  ? 127 THR F N     1 
ATOM   7683  C  CA    . THR E 2 58  ? 218.895 203.954 262.684 1.00 84.53  ? 127 THR F CA    1 
ATOM   7684  C  C     . THR E 2 58  ? 219.179 203.829 261.187 1.00 77.58  ? 127 THR F C     1 
ATOM   7685  O  O     . THR E 2 58  ? 218.287 203.468 260.420 1.00 76.80  ? 127 THR F O     1 
ATOM   7686  C  CB    . THR E 2 58  ? 218.580 205.398 263.068 1.00 85.51  ? 127 THR F CB    1 
ATOM   7687  O  OG1   . THR E 2 58  ? 218.341 205.438 264.473 1.00 85.39  ? 127 THR F OG1   1 
ATOM   7688  C  CG2   . THR E 2 58  ? 217.342 205.904 262.353 1.00 87.01  ? 127 THR F CG2   1 
ATOM   7689  N  N     . ALA E 2 59  ? 220.409 204.145 260.768 1.00 75.51  ? 128 ALA F N     1 
ATOM   7690  C  CA    . ALA E 2 59  ? 220.771 204.059 259.359 1.00 76.15  ? 128 ALA F CA    1 
ATOM   7691  C  C     . ALA E 2 59  ? 220.650 202.621 258.855 1.00 79.60  ? 128 ALA F C     1 
ATOM   7692  O  O     . ALA E 2 59  ? 220.154 202.390 257.752 1.00 78.23  ? 128 ALA F O     1 
ATOM   7693  C  CB    . ALA E 2 59  ? 222.162 204.605 259.128 1.00 77.03  ? 128 ALA F CB    1 
ATOM   7694  N  N     . LYS E 2 60  ? 221.116 201.653 259.653 1.00 82.54  ? 129 LYS F N     1 
ATOM   7695  C  CA    . LYS E 2 60  ? 220.941 200.249 259.312 1.00 82.25  ? 129 LYS F CA    1 
ATOM   7696  C  C     . LYS E 2 60  ? 219.455 199.893 259.264 1.00 78.90  ? 129 LYS F C     1 
ATOM   7697  O  O     . LYS E 2 60  ? 219.004 199.227 258.338 1.00 76.78  ? 129 LYS F O     1 
ATOM   7698  C  CB    . LYS E 2 60  ? 221.678 199.352 260.308 1.00 84.31  ? 129 LYS F CB    1 
ATOM   7699  C  CG    . LYS E 2 60  ? 223.175 199.300 260.099 1.00 88.42  ? 129 LYS F CG    1 
ATOM   7700  C  CD    . LYS E 2 60  ? 223.942 199.022 261.384 1.00 92.60  ? 129 LYS F CD    1 
ATOM   7701  C  CE    . LYS E 2 60  ? 225.306 198.470 261.123 1.00 97.00  ? 129 LYS F CE    1 
ATOM   7702  N  NZ    . LYS E 2 60  ? 226.001 199.143 260.019 1.00 99.09  ? 129 LYS F NZ    1 
ATOM   7703  N  N     . LYS E 2 61  ? 218.692 200.353 260.259 1.00 79.40  ? 130 LYS F N     1 
ATOM   7704  C  CA    . LYS E 2 61  ? 217.275 200.038 260.337 1.00 81.75  ? 130 LYS F CA    1 
ATOM   7705  C  C     . LYS E 2 61  ? 216.541 200.495 259.076 1.00 78.39  ? 130 LYS F C     1 
ATOM   7706  O  O     . LYS E 2 61  ? 215.675 199.784 258.570 1.00 78.99  ? 130 LYS F O     1 
ATOM   7707  C  CB    . LYS E 2 61  ? 216.661 200.687 261.579 1.00 89.36  ? 130 LYS F CB    1 
ATOM   7708  C  CG    . LYS E 2 61  ? 215.192 200.385 261.772 1.00 96.78  ? 130 LYS F CG    1 
ATOM   7709  C  CD    . LYS E 2 61  ? 214.613 201.039 263.018 1.00 102.87 ? 130 LYS F CD    1 
ATOM   7710  C  CE    . LYS E 2 61  ? 213.141 200.807 263.125 1.00 107.93 ? 130 LYS F CE    1 
ATOM   7711  N  NZ    . LYS E 2 61  ? 212.551 201.425 264.315 1.00 109.94 ? 130 LYS F NZ    1 
ATOM   7712  N  N     . LYS E 2 62  ? 216.874 201.687 258.575 1.00 75.96  ? 131 LYS F N     1 
ATOM   7713  C  CA    . LYS E 2 62  ? 216.210 202.217 257.392 1.00 74.38  ? 131 LYS F CA    1 
ATOM   7714  C  C     . LYS E 2 62  ? 216.583 201.418 256.145 1.00 69.21  ? 131 LYS F C     1 
ATOM   7715  O  O     . LYS E 2 62  ? 215.764 201.262 255.240 1.00 67.91  ? 131 LYS F O     1 
ATOM   7716  C  CB    . LYS E 2 62  ? 216.538 203.700 257.200 1.00 79.34  ? 131 LYS F CB    1 
ATOM   7717  C  CG    . LYS E 2 62  ? 215.881 204.611 258.213 1.00 84.86  ? 131 LYS F CG    1 
ATOM   7718  C  CD    . LYS E 2 62  ? 215.940 206.081 257.821 1.00 90.03  ? 131 LYS F CD    1 
ATOM   7719  C  CE    . LYS E 2 62  ? 215.901 207.016 258.994 1.00 93.52  ? 131 LYS F CE    1 
ATOM   7720  N  NZ    . LYS E 2 62  ? 217.230 207.489 259.402 1.00 93.29  ? 131 LYS F NZ    1 
ATOM   7721  N  N     . TYR E 2 63  ? 217.819 200.913 256.089 1.00 66.43  ? 132 TYR F N     1 
ATOM   7722  C  CA    . TYR E 2 63  ? 218.277 200.184 254.916 1.00 66.17  ? 132 TYR F CA    1 
ATOM   7723  C  C     . TYR E 2 63  ? 217.656 198.786 254.863 1.00 67.50  ? 132 TYR F C     1 
ATOM   7724  O  O     . TYR E 2 63  ? 217.226 198.338 253.800 1.00 66.37  ? 132 TYR F O     1 
ATOM   7725  C  CB    . TYR E 2 63  ? 219.804 200.121 254.890 1.00 66.79  ? 132 TYR F CB    1 
ATOM   7726  C  CG    . TYR E 2 63  ? 220.354 199.449 253.644 1.00 69.57  ? 132 TYR F CG    1 
ATOM   7727  C  CD1   . TYR E 2 63  ? 220.172 200.021 252.390 1.00 72.61  ? 132 TYR F CD1   1 
ATOM   7728  C  CD2   . TYR E 2 63  ? 221.061 198.257 253.721 1.00 70.16  ? 132 TYR F CD2   1 
ATOM   7729  C  CE1   . TYR E 2 63  ? 220.669 199.421 251.246 1.00 73.74  ? 132 TYR F CE1   1 
ATOM   7730  C  CE2   . TYR E 2 63  ? 221.566 197.651 252.585 1.00 71.15  ? 132 TYR F CE2   1 
ATOM   7731  C  CZ    . TYR E 2 63  ? 221.367 198.231 251.344 1.00 73.06  ? 132 TYR F CZ    1 
ATOM   7732  O  OH    . TYR E 2 63  ? 221.865 197.632 250.226 1.00 74.64  ? 132 TYR F OH    1 
ATOM   7733  N  N     . LEU E 2 64  ? 217.618 198.091 256.005 1.00 68.12  ? 133 LEU F N     1 
ATOM   7734  C  CA    . LEU E 2 64  ? 216.988 196.778 256.076 1.00 70.32  ? 133 LEU F CA    1 
ATOM   7735  C  C     . LEU E 2 64  ? 215.495 196.882 255.757 1.00 67.93  ? 133 LEU F C     1 
ATOM   7736  O  O     . LEU E 2 64  ? 214.946 196.028 255.063 1.00 68.47  ? 133 LEU F O     1 
ATOM   7737  C  CB    . LEU E 2 64  ? 217.193 196.125 257.444 1.00 73.89  ? 133 LEU F CB    1 
ATOM   7738  C  CG    . LEU E 2 64  ? 218.512 195.383 257.689 1.00 78.59  ? 133 LEU F CG    1 
ATOM   7739  C  CD1   . LEU E 2 64  ? 219.726 196.292 257.769 1.00 81.63  ? 133 LEU F CD1   1 
ATOM   7740  C  CD2   . LEU E 2 64  ? 218.370 194.597 258.980 1.00 83.87  ? 133 LEU F CD2   1 
ATOM   7741  N  N     . LYS E 2 65  ? 214.824 197.902 256.298 1.00 66.70  ? 134 LYS F N     1 
ATOM   7742  C  CA    . LYS E 2 65  ? 213.414 198.103 256.006 1.00 68.26  ? 134 LYS F CA    1 
ATOM   7743  C  C     . LYS E 2 65  ? 213.212 198.290 254.502 1.00 65.47  ? 134 LYS F C     1 
ATOM   7744  O  O     . LYS E 2 65  ? 212.223 197.820 253.942 1.00 66.98  ? 134 LYS F O     1 
ATOM   7745  C  CB    . LYS E 2 65  ? 212.865 199.305 256.772 1.00 75.37  ? 134 LYS F CB    1 
ATOM   7746  C  CG    . LYS E 2 65  ? 211.368 199.488 256.635 1.00 82.80  ? 134 LYS F CG    1 
ATOM   7747  C  CD    . LYS E 2 65  ? 210.820 200.613 257.499 1.00 91.50  ? 134 LYS F CD    1 
ATOM   7748  C  CE    . LYS E 2 65  ? 211.262 201.976 257.058 1.00 96.10  ? 134 LYS F CE    1 
ATOM   7749  N  NZ    . LYS E 2 65  ? 210.739 203.027 257.937 1.00 98.36  ? 134 LYS F NZ    1 
ATOM   7750  N  N     . TYR E 2 66  ? 214.160 198.969 253.851 1.00 61.95  ? 135 TYR F N     1 
ATOM   7751  C  CA    . TYR E 2 66  ? 214.130 199.116 252.405 1.00 59.88  ? 135 TYR F CA    1 
ATOM   7752  C  C     . TYR E 2 66  ? 214.300 197.766 251.711 1.00 61.79  ? 135 TYR F C     1 
ATOM   7753  O  O     . TYR E 2 66  ? 213.608 197.485 250.735 1.00 61.41  ? 135 TYR F O     1 
ATOM   7754  C  CB    . TYR E 2 66  ? 215.220 200.088 251.962 1.00 57.22  ? 135 TYR F CB    1 
ATOM   7755  C  CG    . TYR E 2 66  ? 215.378 200.172 250.458 1.00 55.82  ? 135 TYR F CG    1 
ATOM   7756  C  CD1   . TYR E 2 66  ? 214.422 200.818 249.693 1.00 56.55  ? 135 TYR F CD1   1 
ATOM   7757  C  CD2   . TYR E 2 66  ? 216.473 199.612 249.816 1.00 54.05  ? 135 TYR F CD2   1 
ATOM   7758  C  CE1   . TYR E 2 66  ? 214.550 200.908 248.324 1.00 57.99  ? 135 TYR F CE1   1 
ATOM   7759  C  CE2   . TYR E 2 66  ? 216.621 199.703 248.443 1.00 55.40  ? 135 TYR F CE2   1 
ATOM   7760  C  CZ    . TYR E 2 66  ? 215.660 200.371 247.704 1.00 57.69  ? 135 TYR F CZ    1 
ATOM   7761  O  OH    . TYR E 2 66  ? 215.767 200.480 246.358 1.00 63.54  ? 135 TYR F OH    1 
ATOM   7762  N  N     . LEU E 2 67  ? 215.231 196.937 252.196 1.00 63.06  ? 136 LEU F N     1 
ATOM   7763  C  CA    . LEU E 2 67  ? 215.448 195.633 251.587 1.00 62.52  ? 136 LEU F CA    1 
ATOM   7764  C  C     . LEU E 2 67  ? 214.238 194.730 251.822 1.00 63.16  ? 136 LEU F C     1 
ATOM   7765  O  O     . LEU E 2 67  ? 213.895 193.922 250.962 1.00 65.20  ? 136 LEU F O     1 
ATOM   7766  C  CB    . LEU E 2 67  ? 216.720 194.991 252.132 1.00 61.03  ? 136 LEU F CB    1 
ATOM   7767  C  CG    . LEU E 2 67  ? 218.030 195.744 251.891 1.00 60.07  ? 136 LEU F CG    1 
ATOM   7768  C  CD1   . LEU E 2 67  ? 219.142 195.062 252.667 1.00 59.69  ? 136 LEU F CD1   1 
ATOM   7769  C  CD2   . LEU E 2 67  ? 218.375 195.831 250.417 1.00 59.48  ? 136 LEU F CD2   1 
ATOM   7770  N  N     . TYR E 2 68  ? 213.603 194.859 252.992 1.00 65.36  ? 137 TYR F N     1 
ATOM   7771  C  CA    . TYR E 2 68  ? 212.429 194.060 253.316 1.00 69.26  ? 137 TYR F CA    1 
ATOM   7772  C  C     . TYR E 2 68  ? 211.288 194.368 252.347 1.00 67.59  ? 137 TYR F C     1 
ATOM   7773  O  O     . TYR E 2 68  ? 210.682 193.454 251.789 1.00 70.89  ? 137 TYR F O     1 
ATOM   7774  C  CB    . TYR E 2 68  ? 212.015 194.304 254.769 1.00 75.30  ? 137 TYR F CB    1 
ATOM   7775  C  CG    . TYR E 2 68  ? 210.620 193.815 255.127 1.00 84.21  ? 137 TYR F CG    1 
ATOM   7776  C  CD1   . TYR E 2 68  ? 209.510 194.635 254.958 1.00 89.37  ? 137 TYR F CD1   1 
ATOM   7777  C  CD2   . TYR E 2 68  ? 210.415 192.541 255.641 1.00 88.96  ? 137 TYR F CD2   1 
ATOM   7778  C  CE1   . TYR E 2 68  ? 208.236 194.198 255.284 1.00 94.25  ? 137 TYR F CE1   1 
ATOM   7779  C  CE2   . TYR E 2 68  ? 209.147 192.094 255.975 1.00 93.79  ? 137 TYR F CE2   1 
ATOM   7780  C  CZ    . TYR E 2 68  ? 208.054 192.924 255.794 1.00 96.66  ? 137 TYR F CZ    1 
ATOM   7781  O  OH    . TYR E 2 68  ? 206.800 192.492 256.116 1.00 99.61  ? 137 TYR F OH    1 
ATOM   7782  N  N     . THR E 2 69  ? 210.989 195.654 252.152 1.00 67.46  ? 138 THR F N     1 
ATOM   7783  C  CA    . THR E 2 69  ? 209.861 196.044 251.312 1.00 66.92  ? 138 THR F CA    1 
ATOM   7784  C  C     . THR E 2 69  ? 210.172 195.809 249.834 1.00 64.46  ? 138 THR F C     1 
ATOM   7785  O  O     . THR E 2 69  ? 209.250 195.680 249.032 1.00 64.14  ? 138 THR F O     1 
ATOM   7786  C  CB    . THR E 2 69  ? 209.482 197.504 251.563 1.00 68.52  ? 138 THR F CB    1 
ATOM   7787  O  OG1   . THR E 2 69  ? 208.351 197.815 250.752 1.00 68.69  ? 138 THR F OG1   1 
ATOM   7788  C  CG2   . THR E 2 69  ? 210.612 198.460 251.227 1.00 70.66  ? 138 THR F CG2   1 
ATOM   7789  N  N     . LYS E 2 70  ? 211.457 195.776 249.464 1.00 62.66  ? 139 LYS F N     1 
ATOM   7790  C  CA    . LYS E 2 70  ? 211.826 195.560 248.074 1.00 65.34  ? 139 LYS F CA    1 
ATOM   7791  C  C     . LYS E 2 70  ? 211.456 194.140 247.639 1.00 68.36  ? 139 LYS F C     1 
ATOM   7792  O  O     . LYS E 2 70  ? 210.822 193.946 246.605 1.00 66.77  ? 139 LYS F O     1 
ATOM   7793  C  CB    . LYS E 2 70  ? 213.317 195.828 247.861 1.00 65.83  ? 139 LYS F CB    1 
ATOM   7794  C  CG    . LYS E 2 70  ? 213.783 195.630 246.433 1.00 67.45  ? 139 LYS F CG    1 
ATOM   7795  C  CD    . LYS E 2 70  ? 215.299 195.634 246.297 1.00 70.79  ? 139 LYS F CD    1 
ATOM   7796  C  CE    . LYS E 2 70  ? 215.912 196.980 246.425 1.00 71.58  ? 139 LYS F CE    1 
ATOM   7797  N  NZ    . LYS E 2 70  ? 217.367 196.933 246.247 1.00 73.08  ? 139 LYS F NZ    1 
ATOM   7798  N  N     . GLU E 2 71  ? 211.869 193.136 248.417 1.00 73.17  ? 140 GLU F N     1 
ATOM   7799  C  CA    . GLU E 2 71  ? 211.595 191.755 248.047 1.00 77.18  ? 140 GLU F CA    1 
ATOM   7800  C  C     . GLU E 2 71  ? 210.113 191.422 248.229 1.00 73.42  ? 140 GLU F C     1 
ATOM   7801  O  O     . GLU E 2 71  ? 209.569 190.582 247.514 1.00 74.51  ? 140 GLU F O     1 
ATOM   7802  C  CB    . GLU E 2 71  ? 212.471 190.786 248.835 1.00 80.42  ? 140 GLU F CB    1 
ATOM   7803  C  CG    . GLU E 2 71  ? 212.099 190.670 250.308 1.00 83.78  ? 140 GLU F CG    1 
ATOM   7804  C  CD    . GLU E 2 71  ? 212.923 189.617 251.029 1.00 89.71  ? 140 GLU F CD    1 
ATOM   7805  O  OE1   . GLU E 2 71  ? 213.839 189.038 250.403 1.00 89.56  ? 140 GLU F OE1   1 
ATOM   7806  O  OE2   . GLU E 2 71  ? 212.647 189.376 252.222 1.00 92.26  ? 140 GLU F OE2   1 
ATOM   7807  N  N     . LYS E 2 72  ? 209.459 192.087 249.184 1.00 70.21  ? 141 LYS F N     1 
ATOM   7808  C  CA    . LYS E 2 72  ? 208.050 191.833 249.443 1.00 70.70  ? 141 LYS F CA    1 
ATOM   7809  C  C     . LYS E 2 72  ? 207.191 192.231 248.241 1.00 68.16  ? 141 LYS F C     1 
ATOM   7810  O  O     . LYS E 2 72  ? 206.239 191.533 247.903 1.00 68.79  ? 141 LYS F O     1 
ATOM   7811  C  CB    . LYS E 2 72  ? 207.624 192.548 250.726 1.00 76.79  ? 141 LYS F CB    1 
ATOM   7812  C  CG    . LYS E 2 72  ? 206.143 192.457 251.059 1.00 83.80  ? 141 LYS F CG    1 
ATOM   7813  C  CD    . LYS E 2 72  ? 205.363 193.712 250.688 1.00 91.07  ? 141 LYS F CD    1 
ATOM   7814  C  CE    . LYS E 2 72  ? 205.671 194.837 251.641 1.00 96.43  ? 141 LYS F CE    1 
ATOM   7815  N  NZ    . LYS E 2 72  ? 204.961 196.086 251.345 1.00 98.69  ? 141 LYS F NZ    1 
ATOM   7816  N  N     . VAL E 2 73  ? 207.522 193.348 247.593 1.00 65.29  ? 142 VAL F N     1 
ATOM   7817  C  CA    . VAL E 2 73  ? 206.786 193.763 246.408 1.00 66.10  ? 142 VAL F CA    1 
ATOM   7818  C  C     . VAL E 2 73  ? 207.239 192.944 245.199 1.00 67.22  ? 142 VAL F C     1 
ATOM   7819  O  O     . VAL E 2 73  ? 206.483 192.777 244.241 1.00 66.90  ? 142 VAL F O     1 
ATOM   7820  C  CB    . VAL E 2 73  ? 206.929 195.275 246.158 1.00 66.87  ? 142 VAL F CB    1 
ATOM   7821  C  CG1   . VAL E 2 73  ? 206.473 196.075 247.371 1.00 69.55  ? 142 VAL F CG1   1 
ATOM   7822  C  CG2   . VAL E 2 73  ? 208.347 195.662 245.758 1.00 65.10  ? 142 VAL F CG2   1 
ATOM   7823  N  N     . LYS E 2 74  ? 208.481 192.447 245.228 1.00 71.00  ? 143 LYS F N     1 
ATOM   7824  C  CA    . LYS E 2 74  ? 208.935 191.519 244.203 1.00 77.84  ? 143 LYS F CA    1 
ATOM   7825  C  C     . LYS E 2 74  ? 208.154 190.208 244.296 1.00 82.84  ? 143 LYS F C     1 
ATOM   7826  O  O     . LYS E 2 74  ? 207.685 189.689 243.283 1.00 84.86  ? 143 LYS F O     1 
ATOM   7827  C  CB    . LYS E 2 74  ? 210.436 191.247 244.314 1.00 80.59  ? 143 LYS F CB    1 
ATOM   7828  C  CG    . LYS E 2 74  ? 211.321 192.408 243.919 1.00 84.93  ? 143 LYS F CG    1 
ATOM   7829  C  CD    . LYS E 2 74  ? 212.800 192.059 244.020 1.00 88.39  ? 143 LYS F CD    1 
ATOM   7830  C  CE    . LYS E 2 74  ? 213.697 193.191 243.639 1.00 92.23  ? 143 LYS F CE    1 
ATOM   7831  N  NZ    . LYS E 2 74  ? 215.113 192.824 243.747 1.00 94.32  ? 143 LYS F NZ    1 
ATOM   7832  N  N     . LYS E 2 75  ? 208.023 189.673 245.514 1.00 85.59  ? 144 LYS F N     1 
ATOM   7833  C  CA    . LYS E 2 75  ? 207.273 188.444 245.718 1.00 88.41  ? 144 LYS F CA    1 
ATOM   7834  C  C     . LYS E 2 75  ? 205.800 188.644 245.359 1.00 86.55  ? 144 LYS F C     1 
ATOM   7835  O  O     . LYS E 2 75  ? 205.199 187.793 244.706 1.00 87.82  ? 144 LYS F O     1 
ATOM   7836  C  CB    . LYS E 2 75  ? 207.409 187.960 247.161 1.00 93.36  ? 144 LYS F CB    1 
ATOM   7837  C  CG    . LYS E 2 75  ? 208.788 187.435 247.505 1.00 99.38  ? 144 LYS F CG    1 
ATOM   7838  C  CD    . LYS E 2 75  ? 208.945 187.096 248.980 1.00 104.29 ? 144 LYS F CD    1 
ATOM   7839  C  CE    . LYS E 2 75  ? 208.027 186.002 249.439 1.00 109.73 ? 144 LYS F CE    1 
ATOM   7840  N  NZ    . LYS E 2 75  ? 208.270 185.633 250.837 1.00 112.20 ? 144 LYS F NZ    1 
ATOM   7841  N  N     . ALA E 2 76  ? 205.218 189.768 245.788 1.00 85.77  ? 145 ALA F N     1 
ATOM   7842  C  CA    . ALA E 2 76  ? 203.809 190.030 245.535 1.00 89.28  ? 145 ALA F CA    1 
ATOM   7843  C  C     . ALA E 2 76  ? 203.531 190.126 244.034 1.00 95.18  ? 145 ALA F C     1 
ATOM   7844  O  O     . ALA E 2 76  ? 202.539 189.583 243.551 1.00 96.77  ? 145 ALA F O     1 
ATOM   7845  C  CB    . ALA E 2 76  ? 203.367 191.282 246.258 1.00 88.88  ? 145 ALA F CB    1 
ATOM   7846  N  N     . ARG E 2 77  ? 204.403 190.819 243.295 1.00 103.53 ? 146 ARG F N     1 
ATOM   7847  C  CA    . ARG E 2 77  ? 204.221 190.952 241.858 1.00 111.61 ? 146 ARG F CA    1 
ATOM   7848  C  C     . ARG E 2 77  ? 204.529 189.630 241.151 1.00 110.61 ? 146 ARG F C     1 
ATOM   7849  O  O     . ARG E 2 77  ? 203.893 189.300 240.150 1.00 110.79 ? 146 ARG F O     1 
ATOM   7850  C  CB    . ARG E 2 77  ? 205.088 192.087 241.306 1.00 120.34 ? 146 ARG F CB    1 
ATOM   7851  C  CG    . ARG E 2 77  ? 204.534 192.731 240.044 1.00 130.27 ? 146 ARG F CG    1 
ATOM   7852  C  CD    . ARG E 2 77  ? 203.132 193.302 240.247 1.00 139.22 ? 146 ARG F CD    1 
ATOM   7853  N  NE    . ARG E 2 77  ? 202.972 193.970 241.544 1.00 145.19 ? 146 ARG F NE    1 
ATOM   7854  C  CZ    . ARG E 2 77  ? 203.518 195.133 241.894 1.00 150.31 ? 146 ARG F CZ    1 
ATOM   7855  N  NH1   . ARG E 2 77  ? 204.268 195.816 241.043 1.00 150.23 ? 146 ARG F NH1   1 
ATOM   7856  N  NH2   . ARG E 2 77  ? 203.303 195.617 243.105 1.00 152.32 ? 146 ARG F NH2   1 
ATOM   7857  N  N     . GLN E 2 78  ? 205.509 188.874 241.660 1.00 110.81 ? 147 GLN F N     1 
ATOM   7858  C  CA    . GLN E 2 78  ? 205.846 187.586 241.068 1.00 114.01 ? 147 GLN F CA    1 
ATOM   7859  C  C     . GLN E 2 78  ? 204.700 186.592 241.260 1.00 113.50 ? 147 GLN F C     1 
ATOM   7860  O  O     . GLN E 2 78  ? 204.337 185.879 240.326 1.00 114.92 ? 147 GLN F O     1 
ATOM   7861  C  CB    . GLN E 2 78  ? 207.142 187.039 241.662 1.00 117.01 ? 147 GLN F CB    1 
ATOM   7862  C  CG    . GLN E 2 78  ? 207.650 185.777 240.974 1.00 120.72 ? 147 GLN F CG    1 
ATOM   7863  C  CD    . GLN E 2 78  ? 208.991 185.314 241.498 1.00 125.66 ? 147 GLN F CD    1 
ATOM   7864  O  OE1   . GLN E 2 78  ? 209.548 185.881 242.446 1.00 129.06 ? 147 GLN F OE1   1 
ATOM   7865  N  NE2   . GLN E 2 78  ? 209.525 184.268 240.885 1.00 127.65 ? 147 GLN F NE2   1 
ATOM   7866  N  N     . ILE E 2 79  ? 204.125 186.543 242.465 1.00 112.54 ? 148 ILE F N     1 
ATOM   7867  C  CA    . ILE E 2 79  ? 202.986 185.670 242.720 1.00 111.17 ? 148 ILE F CA    1 
ATOM   7868  C  C     . ILE E 2 79  ? 201.830 186.045 241.792 1.00 111.41 ? 148 ILE F C     1 
ATOM   7869  O  O     . ILE E 2 79  ? 201.137 185.172 241.269 1.00 115.28 ? 148 ILE F O     1 
ATOM   7870  C  CB    . ILE E 2 79  ? 202.579 185.717 244.204 1.00 110.38 ? 148 ILE F CB    1 
ATOM   7871  C  CG1   . ILE E 2 79  ? 203.661 185.094 245.082 1.00 109.55 ? 148 ILE F CG1   1 
ATOM   7872  C  CG2   . ILE E 2 79  ? 201.221 185.049 244.431 1.00 111.01 ? 148 ILE F CG2   1 
ATOM   7873  C  CD1   . ILE E 2 79  ? 203.484 185.352 246.567 1.00 109.75 ? 148 ILE F CD1   1 
ATOM   7874  N  N     . LYS E 2 80  ? 201.627 187.346 241.578 1.00 114.65 ? 149 LYS F N     1 
ATOM   7875  C  CA    . LYS E 2 80  ? 200.632 187.810 240.626 1.00 118.63 ? 149 LYS F CA    1 
ATOM   7876  C  C     . LYS E 2 80  ? 201.039 187.514 239.182 1.00 121.70 ? 149 LYS F C     1 
ATOM   7877  O  O     . LYS E 2 80  ? 200.218 187.680 238.282 1.00 122.93 ? 149 LYS F O     1 
ATOM   7878  C  CB    . LYS E 2 80  ? 200.357 189.307 240.792 1.00 122.48 ? 149 LYS F CB    1 
ATOM   7879  C  CG    . LYS E 2 80  ? 199.046 189.609 241.486 1.00 129.14 ? 149 LYS F CG    1 
ATOM   7880  C  CD    . LYS E 2 80  ? 198.781 191.100 241.650 1.00 135.06 ? 149 LYS F CD    1 
ATOM   7881  C  CE    . LYS E 2 80  ? 197.431 191.382 242.233 1.00 138.09 ? 149 LYS F CE    1 
ATOM   7882  N  NZ    . LYS E 2 80  ? 197.176 192.817 242.393 1.00 138.68 ? 149 LYS F NZ    1 
ATOM   7883  N  N     . LYS E 2 81  ? 202.289 187.094 238.947 1.00 126.16 ? 150 LYS F N     1 
ATOM   7884  C  CA    . LYS E 2 81  ? 202.731 186.773 237.598 1.00 132.53 ? 150 LYS F CA    1 
ATOM   7885  C  C     . LYS E 2 81  ? 202.357 185.337 237.226 1.00 136.58 ? 150 LYS F C     1 
ATOM   7886  O  O     . LYS E 2 81  ? 201.870 185.088 236.122 1.00 137.42 ? 150 LYS F O     1 
ATOM   7887  C  CB    . LYS E 2 81  ? 204.238 186.994 237.450 1.00 135.95 ? 150 LYS F CB    1 
ATOM   7888  C  CG    . LYS E 2 81  ? 204.765 186.722 236.050 1.00 140.56 ? 150 LYS F CG    1 
ATOM   7889  C  CD    . LYS E 2 81  ? 204.141 187.591 234.963 1.00 142.93 ? 150 LYS F CD    1 
ATOM   7890  C  CE    . LYS E 2 81  ? 204.426 189.053 235.129 1.00 144.86 ? 150 LYS F CE    1 
ATOM   7891  N  NZ    . LYS E 2 81  ? 205.855 189.357 235.002 1.00 146.04 ? 150 LYS F NZ    1 
ATOM   7892  N  N     . GLU E 2 82  ? 202.598 184.381 238.132 1.00 138.96 ? 151 GLU F N     1 
ATOM   7893  C  CA    . GLU E 2 82  ? 202.155 183.013 237.898 1.00 139.71 ? 151 GLU F CA    1 
ATOM   7894  C  C     . GLU E 2 82  ? 200.629 182.953 237.806 1.00 139.71 ? 151 GLU F C     1 
ATOM   7895  O  O     . GLU E 2 82  ? 200.081 182.184 237.017 1.00 141.63 ? 151 GLU F O     1 
ATOM   7896  C  CB    . GLU E 2 82  ? 202.648 182.032 238.962 1.00 141.51 ? 151 GLU F CB    1 
ATOM   7897  C  CG    . GLU E 2 82  ? 204.147 181.755 238.899 1.00 144.24 ? 151 GLU F CG    1 
ATOM   7898  C  CD    . GLU E 2 82  ? 204.976 182.579 239.861 1.00 147.48 ? 151 GLU F CD    1 
ATOM   7899  O  OE1   . GLU E 2 82  ? 204.371 183.242 240.727 1.00 149.60 ? 151 GLU F OE1   1 
ATOM   7900  O  OE2   . GLU E 2 82  ? 206.217 182.550 239.747 1.00 149.35 ? 151 GLU F OE2   1 
ATOM   7901  N  N     . MET E 2 83  ? 199.942 183.765 238.616 1.00 141.46 ? 152 MET F N     1 
ATOM   7902  C  CA    . MET E 2 83  ? 198.493 183.862 238.542 1.00 146.14 ? 152 MET F CA    1 
ATOM   7903  C  C     . MET E 2 83  ? 198.073 184.415 237.178 1.00 148.44 ? 152 MET F C     1 
ATOM   7904  O  O     . MET E 2 83  ? 197.148 183.895 236.556 1.00 150.49 ? 152 MET F O     1 
ATOM   7905  C  CB    . MET E 2 83  ? 197.960 184.733 239.683 1.00 149.20 ? 152 MET F CB    1 
ATOM   7906  C  CG    . MET E 2 83  ? 196.461 184.632 239.922 1.00 153.80 ? 152 MET F CG    1 
ATOM   7907  S  SD    . MET E 2 83  ? 195.435 185.577 238.776 1.00 156.45 ? 152 MET F SD    1 
ATOM   7908  C  CE    . MET E 2 83  ? 196.312 187.146 238.792 1.00 157.60 ? 152 MET F CE    1 
ATOM   7909  N  N     . LYS E 2 84  ? 198.753 185.468 236.713 1.00 154.32 ? 153 LYS F N     1 
ATOM   7910  C  CA    . LYS E 2 84  ? 198.454 186.036 235.408 1.00 159.79 ? 153 LYS F CA    1 
ATOM   7911  C  C     . LYS E 2 84  ? 198.781 185.038 234.297 1.00 160.41 ? 153 LYS F C     1 
ATOM   7912  O  O     . LYS E 2 84  ? 198.015 184.896 233.344 1.00 156.41 ? 153 LYS F O     1 
ATOM   7913  C  CB    . LYS E 2 84  ? 199.222 187.345 235.199 1.00 164.46 ? 153 LYS F CB    1 
ATOM   7914  C  CG    . LYS E 2 84  ? 198.924 188.041 233.881 1.00 170.73 ? 153 LYS F CG    1 
ATOM   7915  C  CD    . LYS E 2 84  ? 197.477 188.496 233.724 1.00 176.08 ? 153 LYS F CD    1 
ATOM   7916  C  CE    . LYS E 2 84  ? 197.099 189.596 234.676 1.00 178.62 ? 153 LYS F CE    1 
ATOM   7917  N  NZ    . LYS E 2 84  ? 195.720 190.054 234.487 1.00 179.26 ? 153 LYS F NZ    1 
ATOM   7918  N  N     . ALA E 2 85  ? 199.923 184.350 234.420 1.00 164.94 ? 154 ALA F N     1 
ATOM   7919  C  CA    . ALA E 2 85  ? 200.341 183.379 233.418 1.00 170.55 ? 154 ALA F CA    1 
ATOM   7920  C  C     . ALA E 2 85  ? 199.371 182.196 233.367 1.00 180.32 ? 154 ALA F C     1 
ATOM   7921  O  O     . ALA E 2 85  ? 199.021 181.723 232.285 1.00 183.91 ? 154 ALA F O     1 
ATOM   7922  C  CB    . ALA E 2 85  ? 201.757 182.917 233.687 1.00 168.40 ? 154 ALA F CB    1 
ATOM   7923  N  N     . ALA E 2 86  ? 198.938 181.715 234.539 1.00 184.78 ? 155 ALA F N     1 
ATOM   7924  C  CA    . ALA E 2 86  ? 198.015 180.589 234.596 1.00 186.03 ? 155 ALA F CA    1 
ATOM   7925  C  C     . ALA E 2 86  ? 196.661 180.967 233.995 1.00 187.61 ? 155 ALA F C     1 
ATOM   7926  O  O     . ALA E 2 86  ? 196.045 180.162 233.301 1.00 193.01 ? 155 ALA F O     1 
ATOM   7927  C  CB    . ALA E 2 86  ? 197.865 180.095 236.018 1.00 186.83 ? 155 ALA F CB    1 
ATOM   7928  N  N     . ALA E 2 87  ? 196.193 182.191 234.262 1.00 190.51 ? 156 ALA F N     1 
ATOM   7929  C  CA    . ALA E 2 87  ? 194.904 182.631 233.744 1.00 198.00 ? 156 ALA F CA    1 
ATOM   7930  C  C     . ALA E 2 87  ? 194.952 182.811 232.226 1.00 209.96 ? 156 ALA F C     1 
ATOM   7931  O  O     . ALA E 2 87  ? 193.925 182.700 231.558 1.00 212.82 ? 156 ALA F O     1 
ATOM   7932  C  CB    . ALA E 2 87  ? 194.465 183.905 234.434 1.00 197.42 ? 156 ALA F CB    1 
ATOM   7933  N  N     . ARG E 2 88  ? 196.138 183.093 231.676 1.00 222.00 ? 157 ARG F N     1 
ATOM   7934  C  CA    . ARG E 2 88  ? 196.263 183.294 230.239 1.00 231.79 ? 157 ARG F CA    1 
ATOM   7935  C  C     . ARG E 2 88  ? 196.152 181.966 229.490 1.00 241.82 ? 157 ARG F C     1 
ATOM   7936  O  O     . ARG E 2 88  ? 195.490 181.889 228.456 1.00 244.09 ? 157 ARG F O     1 
ATOM   7937  C  CB    . ARG E 2 88  ? 197.574 184.010 229.900 1.00 231.70 ? 157 ARG F CB    1 
ATOM   7938  C  CG    . ARG E 2 88  ? 197.553 185.494 230.239 1.00 231.74 ? 157 ARG F CG    1 
ATOM   7939  C  CD    . ARG E 2 88  ? 198.866 186.198 229.928 1.00 229.14 ? 157 ARG F CD    1 
ATOM   7940  N  NE    . ARG E 2 88  ? 199.102 186.289 228.483 1.00 228.31 ? 157 ARG F NE    1 
ATOM   7941  C  CZ    . ARG E 2 88  ? 200.027 185.629 227.790 1.00 228.17 ? 157 ARG F CZ    1 
ATOM   7942  N  NH1   . ARG E 2 88  ? 200.851 184.779 228.380 1.00 226.83 ? 157 ARG F NH1   1 
ATOM   7943  N  NH2   . ARG E 2 88  ? 200.121 185.822 226.487 1.00 228.58 ? 157 ARG F NH2   1 
ATOM   7944  N  N     . GLU E 2 89  ? 196.810 180.920 230.000 1.00 250.67 ? 158 GLU F N     1 
ATOM   7945  C  CA    . GLU E 2 89  ? 196.846 179.645 229.295 1.00 259.32 ? 158 GLU F CA    1 
ATOM   7946  C  C     . GLU E 2 89  ? 195.475 178.968 229.320 1.00 265.98 ? 158 GLU F C     1 
ATOM   7947  O  O     . GLU E 2 89  ? 195.081 178.333 228.346 1.00 269.16 ? 158 GLU F O     1 
ATOM   7948  C  CB    . GLU E 2 89  ? 197.937 178.729 229.846 1.00 260.10 ? 158 GLU F CB    1 
ATOM   7949  C  CG    . GLU E 2 89  ? 197.746 178.321 231.303 1.00 261.90 ? 158 GLU F CG    1 
ATOM   7950  C  CD    . GLU E 2 89  ? 199.017 177.784 231.937 1.00 265.03 ? 158 GLU F CD    1 
ATOM   7951  O  OE1   . GLU E 2 89  ? 200.086 177.886 231.300 1.00 266.17 ? 158 GLU F OE1   1 
ATOM   7952  O  OE2   . GLU E 2 89  ? 198.940 177.255 233.065 1.00 265.91 ? 158 GLU F OE2   1 
ATOM   7953  N  N     . GLU E 2 90  ? 194.742 179.100 230.428 1.00 272.59 ? 159 GLU F N     1 
ATOM   7954  C  CA    . GLU E 2 90  ? 193.420 178.494 230.519 1.00 278.68 ? 159 GLU F CA    1 
ATOM   7955  C  C     . GLU E 2 90  ? 192.450 179.139 229.526 1.00 284.89 ? 159 GLU F C     1 
ATOM   7956  O  O     . GLU E 2 90  ? 191.523 178.480 229.056 1.00 288.60 ? 159 GLU F O     1 
ATOM   7957  C  CB    . GLU E 2 90  ? 192.886 178.556 231.950 1.00 280.26 ? 159 GLU F CB    1 
ATOM   7958  C  CG    . GLU E 2 90  ? 192.607 179.971 232.449 1.00 282.54 ? 159 GLU F CG    1 
ATOM   7959  C  CD    . GLU E 2 90  ? 191.220 180.486 232.105 1.00 284.27 ? 159 GLU F CD    1 
ATOM   7960  O  OE1   . GLU E 2 90  ? 190.318 179.660 231.852 1.00 284.29 ? 159 GLU F OE1   1 
ATOM   7961  O  OE2   . GLU E 2 90  ? 191.042 181.719 232.076 1.00 284.96 ? 159 GLU F OE2   1 
ATOM   7962  N  N     . ALA E 2 91  ? 192.656 180.426 229.216 1.00 289.36 ? 160 ALA F N     1 
ATOM   7963  C  CA    . ALA E 2 91  ? 191.767 181.136 228.305 1.00 294.38 ? 160 ALA F CA    1 
ATOM   7964  C  C     . ALA E 2 91  ? 191.926 180.624 226.873 1.00 301.30 ? 160 ALA F C     1 
ATOM   7965  O  O     . ALA E 2 91  ? 190.936 180.468 226.158 1.00 303.13 ? 160 ALA F O     1 
ATOM   7966  C  CB    . ALA E 2 91  ? 192.008 182.630 228.383 1.00 293.89 ? 160 ALA F CB    1 
ATOM   7967  N  N     . LYS E 2 92  ? 193.169 180.374 226.450 1.00 306.94 ? 161 LYS F N     1 
ATOM   7968  C  CA    . LYS E 2 92  ? 193.432 179.973 225.074 1.00 311.49 ? 161 LYS F CA    1 
ATOM   7969  C  C     . LYS E 2 92  ? 192.972 178.535 224.826 1.00 318.16 ? 161 LYS F C     1 
ATOM   7970  O  O     . LYS E 2 92  ? 192.534 178.210 223.722 1.00 319.21 ? 161 LYS F O     1 
ATOM   7971  C  CB    . LYS E 2 92  ? 194.911 180.145 224.715 1.00 309.39 ? 161 LYS F CB    1 
ATOM   7972  C  CG    . LYS E 2 92  ? 195.868 179.254 225.482 1.00 307.30 ? 161 LYS F CG    1 
ATOM   7973  C  CD    . LYS E 2 92  ? 197.322 179.456 225.081 1.00 307.06 ? 161 LYS F CD    1 
ATOM   7974  C  CE    . LYS E 2 92  ? 198.272 178.699 225.957 1.00 307.16 ? 161 LYS F CE    1 
ATOM   7975  N  NZ    . LYS E 2 92  ? 198.131 177.247 225.821 1.00 306.72 ? 161 LYS F NZ    1 
ATOM   7976  N  N     . ASN E 2 93  ? 193.078 177.673 225.845 1.00 321.56 ? 162 ASN F N     1 
ATOM   7977  C  CA    . ASN E 2 93  ? 192.653 176.286 225.709 1.00 323.62 ? 162 ASN F CA    1 
ATOM   7978  C  C     . ASN E 2 93  ? 191.139 176.198 225.513 1.00 326.55 ? 162 ASN F C     1 
ATOM   7979  O  O     . ASN E 2 93  ? 190.661 175.330 224.782 1.00 327.50 ? 162 ASN F O     1 
ATOM   7980  C  CB    . ASN E 2 93  ? 193.109 175.444 226.894 1.00 322.97 ? 162 ASN F CB    1 
ATOM   7981  C  CG    . ASN E 2 93  ? 194.613 175.321 226.962 1.00 323.15 ? 162 ASN F CG    1 
ATOM   7982  O  OD1   . ASN E 2 93  ? 195.218 175.634 227.993 1.00 322.47 ? 162 ASN F OD1   1 
ATOM   7983  N  ND2   . ASN E 2 93  ? 195.233 174.855 225.887 1.00 323.07 ? 162 ASN F ND2   1 
ATOM   7984  N  N     . ILE E 2 94  ? 190.389 177.084 226.178 1.00 330.60 ? 163 ILE F N     1 
ATOM   7985  C  CA    . ILE E 2 94  ? 188.944 177.127 226.010 1.00 335.55 ? 163 ILE F CA    1 
ATOM   7986  C  C     . ILE E 2 94  ? 188.606 177.485 224.563 1.00 340.23 ? 163 ILE F C     1 
ATOM   7987  O  O     . ILE E 2 94  ? 187.724 176.874 223.960 1.00 342.03 ? 163 ILE F O     1 
ATOM   7988  C  CB    . ILE E 2 94  ? 188.303 178.104 227.012 1.00 335.21 ? 163 ILE F CB    1 
ATOM   7989  C  CG1   . ILE E 2 94  ? 188.348 177.540 228.427 1.00 334.91 ? 163 ILE F CG1   1 
ATOM   7990  C  CG2   . ILE E 2 94  ? 186.874 178.464 226.598 1.00 335.16 ? 163 ILE F CG2   1 
ATOM   7991  C  CD1   . ILE E 2 94  ? 188.155 178.580 229.512 1.00 335.30 ? 163 ILE F CD1   1 
ATOM   7992  N  N     . LYS E 2 95  ? 189.312 178.481 224.015 1.00 341.43 ? 164 LYS F N     1 
ATOM   7993  C  CA    . LYS E 2 95  ? 189.077 178.928 222.650 1.00 342.08 ? 164 LYS F CA    1 
ATOM   7994  C  C     . LYS E 2 95  ? 189.678 177.914 221.662 1.00 340.16 ? 164 LYS F C     1 
ATOM   7995  O  O     . LYS E 2 95  ? 188.895 177.083 221.142 1.00 336.95 ? 164 LYS F O     1 
ATOM   7996  C  CB    . LYS E 2 95  ? 189.689 180.315 222.442 1.00 342.72 ? 164 LYS F CB    1 
ATOM   7997  C  CG    . LYS E 2 95  ? 189.107 181.381 223.346 1.00 342.97 ? 164 LYS F CG    1 
ATOM   7998  C  CD    . LYS E 2 95  ? 190.079 182.521 223.617 1.00 342.57 ? 164 LYS F CD    1 
ATOM   7999  C  CE    . LYS E 2 95  ? 189.710 183.322 224.827 1.00 341.20 ? 164 LYS F CE    1 
ATOM   8000  N  NZ    . LYS E 2 95  ? 190.753 184.285 225.199 1.00 340.23 ? 164 LYS F NZ    1 
ATOM   8001  N  N     . LYS E 2 106 ? 191.469 187.778 206.706 1.00 61.36  ? 175 LYS F N     1 
ATOM   8002  C  CA    . LYS E 2 106 ? 190.935 189.148 206.927 1.00 58.66  ? 175 LYS F CA    1 
ATOM   8003  C  C     . LYS E 2 106 ? 191.890 190.168 206.308 1.00 52.93  ? 175 LYS F C     1 
ATOM   8004  O  O     . LYS E 2 106 ? 193.069 189.886 206.113 1.00 55.05  ? 175 LYS F O     1 
ATOM   8005  C  CB    . LYS E 2 106 ? 190.732 189.398 208.424 1.00 61.45  ? 175 LYS F CB    1 
ATOM   8006  C  CG    . LYS E 2 106 ? 190.054 190.709 208.750 1.00 65.18  ? 175 LYS F CG    1 
ATOM   8007  C  CD    . LYS E 2 106 ? 189.866 190.941 210.242 1.00 68.28  ? 175 LYS F CD    1 
ATOM   8008  C  CE    . LYS E 2 106 ? 189.291 192.298 210.518 1.00 70.74  ? 175 LYS F CE    1 
ATOM   8009  N  NZ    . LYS E 2 106 ? 190.197 193.398 210.163 1.00 70.00  ? 175 LYS F NZ    1 
ATOM   8010  N  N     . ASN E 2 107 ? 191.354 191.354 206.000 1.00 44.53  ? 176 ASN F N     1 
ATOM   8011  C  CA    . ASN E 2 107 ? 192.082 192.391 205.288 1.00 38.37  ? 176 ASN F CA    1 
ATOM   8012  C  C     . ASN E 2 107 ? 192.592 193.439 206.278 1.00 35.31  ? 176 ASN F C     1 
ATOM   8013  O  O     . ASN E 2 107 ? 191.813 194.061 206.998 1.00 36.47  ? 176 ASN F O     1 
ATOM   8014  C  CB    . ASN E 2 107 ? 191.193 193.030 204.226 1.00 37.93  ? 176 ASN F CB    1 
ATOM   8015  C  CG    . ASN E 2 107 ? 190.848 192.081 203.098 1.00 35.77  ? 176 ASN F CG    1 
ATOM   8016  O  OD1   . ASN E 2 107 ? 191.597 191.140 202.810 1.00 35.61  ? 176 ASN F OD1   1 
ATOM   8017  N  ND2   . ASN E 2 107 ? 189.731 192.320 202.426 1.00 36.41  ? 176 ASN F ND2   1 
ATOM   8018  N  N     . PHE E 2 108 ? 193.915 193.626 206.305 1.00 29.46  ? 177 PHE F N     1 
ATOM   8019  C  CA    . PHE E 2 108 ? 194.550 194.651 207.118 1.00 25.70  ? 177 PHE F CA    1 
ATOM   8020  C  C     . PHE E 2 108 ? 195.420 195.524 206.224 1.00 22.99  ? 177 PHE F C     1 
ATOM   8021  O  O     . PHE E 2 108 ? 195.939 195.064 205.204 1.00 22.12  ? 177 PHE F O     1 
ATOM   8022  C  CB    . PHE E 2 108 ? 195.429 194.020 208.199 1.00 26.70  ? 177 PHE F CB    1 
ATOM   8023  C  CG    . PHE E 2 108 ? 194.655 193.255 209.258 1.00 29.91  ? 177 PHE F CG    1 
ATOM   8024  C  CD1   . PHE E 2 108 ? 194.393 191.905 209.105 1.00 30.96  ? 177 PHE F CD1   1 
ATOM   8025  C  CD2   . PHE E 2 108 ? 194.202 193.893 210.404 1.00 31.66  ? 177 PHE F CD2   1 
ATOM   8026  C  CE1   . PHE E 2 108 ? 193.686 191.206 210.071 1.00 32.54  ? 177 PHE F CE1   1 
ATOM   8027  C  CE2   . PHE E 2 108 ? 193.510 193.188 211.377 1.00 31.34  ? 177 PHE F CE2   1 
ATOM   8028  C  CZ    . PHE E 2 108 ? 193.242 191.850 211.204 1.00 31.21  ? 177 PHE F CZ    1 
ATOM   8029  N  N     . LEU E 2 109 ? 195.601 196.783 206.621 1.00 21.69  ? 178 LEU F N     1 
ATOM   8030  C  CA    . LEU E 2 109 ? 196.480 197.675 205.879 1.00 23.07  ? 178 LEU F CA    1 
ATOM   8031  C  C     . LEU E 2 109 ? 197.896 197.643 206.451 1.00 20.14  ? 178 LEU F C     1 
ATOM   8032  O  O     . LEU E 2 109 ? 198.851 197.875 205.713 1.00 21.44  ? 178 LEU F O     1 
ATOM   8033  C  CB    . LEU E 2 109 ? 195.928 199.095 205.842 1.00 25.94  ? 178 LEU F CB    1 
ATOM   8034  C  CG    . LEU E 2 109 ? 196.743 200.118 205.039 1.00 30.10  ? 178 LEU F CG    1 
ATOM   8035  C  CD1   . LEU E 2 109 ? 196.799 199.784 203.560 1.00 30.15  ? 178 LEU F CD1   1 
ATOM   8036  C  CD2   . LEU E 2 109 ? 196.168 201.514 205.219 1.00 34.16  ? 178 LEU F CD2   1 
ATOM   8037  N  N     . PHE E 2 110 ? 198.028 197.387 207.757 1.00 18.40  ? 179 PHE F N     1 
ATOM   8038  C  CA    . PHE E 2 110 ? 199.325 197.387 208.409 1.00 19.17  ? 179 PHE F CA    1 
ATOM   8039  C  C     . PHE E 2 110 ? 199.504 196.110 209.216 1.00 17.27  ? 179 PHE F C     1 
ATOM   8040  O  O     . PHE E 2 110 ? 198.560 195.609 209.815 1.00 17.30  ? 179 PHE F O     1 
ATOM   8041  C  CB    . PHE E 2 110 ? 199.480 198.580 209.359 1.00 20.20  ? 179 PHE F CB    1 
ATOM   8042  C  CG    . PHE E 2 110 ? 199.110 199.909 208.740 1.00 23.24  ? 179 PHE F CG    1 
ATOM   8043  C  CD1   . PHE E 2 110 ? 199.978 200.565 207.885 1.00 24.70  ? 179 PHE F CD1   1 
ATOM   8044  C  CD2   . PHE E 2 110 ? 197.894 200.498 209.045 1.00 26.13  ? 179 PHE F CD2   1 
ATOM   8045  C  CE1   . PHE E 2 110 ? 199.641 201.802 207.361 1.00 27.35  ? 179 PHE F CE1   1 
ATOM   8046  C  CE2   . PHE E 2 110 ? 197.557 201.729 208.507 1.00 27.17  ? 179 PHE F CE2   1 
ATOM   8047  C  CZ    . PHE E 2 110 ? 198.430 202.373 207.665 1.00 26.73  ? 179 PHE F CZ    1 
ATOM   8048  N  N     . LEU E 2 111 ? 200.745 195.622 209.258 1.00 16.20  ? 180 LEU F N     1 
ATOM   8049  C  CA    . LEU E 2 111 ? 201.148 194.652 210.258 1.00 16.23  ? 180 LEU F CA    1 
ATOM   8050  C  C     . LEU E 2 111 ? 201.237 195.347 211.614 1.00 15.63  ? 180 LEU F C     1 
ATOM   8051  O  O     . LEU E 2 111 ? 201.538 196.532 211.706 1.00 16.33  ? 180 LEU F O     1 
ATOM   8052  C  CB    . LEU E 2 111 ? 202.494 194.046 209.872 1.00 16.48  ? 180 LEU F CB    1 
ATOM   8053  C  CG    . LEU E 2 111 ? 202.548 193.229 208.584 1.00 17.36  ? 180 LEU F CG    1 
ATOM   8054  C  CD1   . LEU E 2 111 ? 203.994 192.949 208.220 1.00 17.37  ? 180 LEU F CD1   1 
ATOM   8055  C  CD2   . LEU E 2 111 ? 201.757 191.937 208.695 1.00 17.68  ? 180 LEU F CD2   1 
ATOM   8056  N  N     . ARG E 2 112 ? 201.015 194.587 212.681 1.00 15.93  ? 181 ARG F N     1 
ATOM   8057  C  CA    . ARG E 2 112 ? 201.097 195.130 214.026 1.00 16.11  ? 181 ARG F CA    1 
ATOM   8058  C  C     . ARG E 2 112 ? 202.570 195.262 214.420 1.00 15.85  ? 181 ARG F C     1 
ATOM   8059  O  O     . ARG E 2 112 ? 203.156 194.352 215.008 1.00 16.27  ? 181 ARG F O     1 
ATOM   8060  C  CB    . ARG E 2 112 ? 200.278 194.279 215.002 1.00 17.06  ? 181 ARG F CB    1 
ATOM   8061  C  CG    . ARG E 2 112 ? 200.252 194.859 216.408 1.00 17.63  ? 181 ARG F CG    1 
ATOM   8062  C  CD    . ARG E 2 112 ? 199.408 194.027 217.348 1.00 17.88  ? 181 ARG F CD    1 
ATOM   8063  N  NE    . ARG E 2 112 ? 200.029 192.721 217.565 1.00 17.18  ? 181 ARG F NE    1 
ATOM   8064  C  CZ    . ARG E 2 112 ? 199.546 191.790 218.363 1.00 17.76  ? 181 ARG F CZ    1 
ATOM   8065  N  NH1   . ARG E 2 112 ? 198.413 192.011 219.008 1.00 18.20  ? 181 ARG F NH1   1 
ATOM   8066  N  NH2   . ARG E 2 112 ? 200.210 190.658 218.519 1.00 17.51  ? 181 ARG F NH2   1 
ATOM   8067  N  N     . LEU E 2 113 ? 203.156 196.411 214.069 1.00 15.66  ? 182 LEU F N     1 
ATOM   8068  C  CA    . LEU E 2 113 ? 204.540 196.724 214.398 1.00 16.90  ? 182 LEU F CA    1 
ATOM   8069  C  C     . LEU E 2 113 ? 204.655 198.118 215.024 1.00 16.95  ? 182 LEU F C     1 
ATOM   8070  O  O     . LEU E 2 113 ? 205.631 198.830 214.788 1.00 19.13  ? 182 LEU F O     1 
ATOM   8071  C  CB    . LEU E 2 113 ? 205.377 196.622 213.124 1.00 16.84  ? 182 LEU F CB    1 
ATOM   8072  C  CG    . LEU E 2 113 ? 205.510 195.220 212.520 1.00 17.43  ? 182 LEU F CG    1 
ATOM   8073  C  CD1   . LEU E 2 113 ? 206.194 195.290 211.160 1.00 17.91  ? 182 LEU F CD1   1 
ATOM   8074  C  CD2   . LEU E 2 113 ? 206.255 194.274 213.446 1.00 17.88  ? 182 LEU F CD2   1 
ATOM   8075  N  N     . TRP E 2 114 ? 203.653 198.515 215.811 1.00 17.58  ? 183 TRP F N     1 
ATOM   8076  C  CA    . TRP E 2 114 ? 203.508 199.908 216.199 1.00 19.06  ? 183 TRP F CA    1 
ATOM   8077  C  C     . TRP E 2 114 ? 204.586 200.360 217.178 1.00 19.70  ? 183 TRP F C     1 
ATOM   8078  O  O     . TRP E 2 114 ? 205.110 201.468 217.054 1.00 20.23  ? 183 TRP F O     1 
ATOM   8079  C  CB    . TRP E 2 114 ? 202.108 200.155 216.764 1.00 18.73  ? 183 TRP F CB    1 
ATOM   8080  C  CG    . TRP E 2 114 ? 201.050 199.771 215.776 1.00 18.77  ? 183 TRP F CG    1 
ATOM   8081  C  CD1   . TRP E 2 114 ? 200.162 198.745 215.892 1.00 18.59  ? 183 TRP F CD1   1 
ATOM   8082  C  CD2   . TRP E 2 114 ? 200.828 200.355 214.480 1.00 18.72  ? 183 TRP F CD2   1 
ATOM   8083  N  NE1   . TRP E 2 114 ? 199.384 198.665 214.774 1.00 18.46  ? 183 TRP F NE1   1 
ATOM   8084  C  CE2   . TRP E 2 114 ? 199.771 199.632 213.887 1.00 18.72  ? 183 TRP F CE2   1 
ATOM   8085  C  CE3   . TRP E 2 114 ? 201.403 201.415 213.776 1.00 19.53  ? 183 TRP F CE3   1 
ATOM   8086  C  CZ2   . TRP E 2 114 ? 199.274 199.940 212.627 1.00 18.54  ? 183 TRP F CZ2   1 
ATOM   8087  C  CZ3   . TRP E 2 114 ? 200.908 201.723 212.527 1.00 19.58  ? 183 TRP F CZ3   1 
ATOM   8088  C  CH2   . TRP E 2 114 ? 199.865 200.983 211.955 1.00 19.66  ? 183 TRP F CH2   1 
ATOM   8089  N  N     . ASP E 2 115 ? 204.901 199.516 218.159 1.00 21.22  ? 184 ASP F N     1 
ATOM   8090  C  CA    . ASP E 2 115 ? 205.895 199.859 219.157 1.00 23.03  ? 184 ASP F CA    1 
ATOM   8091  C  C     . ASP E 2 115 ? 207.245 200.116 218.491 1.00 21.59  ? 184 ASP F C     1 
ATOM   8092  O  O     . ASP E 2 115 ? 207.936 201.071 218.837 1.00 20.84  ? 184 ASP F O     1 
ATOM   8093  C  CB    . ASP E 2 115 ? 205.994 198.787 220.227 1.00 27.89  ? 184 ASP F CB    1 
ATOM   8094  C  CG    . ASP E 2 115 ? 206.625 199.272 221.521 1.00 35.32  ? 184 ASP F CG    1 
ATOM   8095  O  OD1   . ASP E 2 115 ? 207.567 198.601 222.019 1.00 40.07  ? 184 ASP F OD1   1 
ATOM   8096  O  OD2   . ASP E 2 115 ? 206.175 200.335 222.013 1.00 40.64  ? 184 ASP F OD2   1 
ATOM   8097  N  N     . ARG E 2 116 ? 207.623 199.256 217.541 1.00 21.14  ? 185 ARG F N     1 
ATOM   8098  C  CA    . ARG E 2 116 ? 208.854 199.437 216.793 1.00 21.51  ? 185 ARG F CA    1 
ATOM   8099  C  C     . ARG E 2 116 ? 208.772 200.708 215.947 1.00 19.63  ? 185 ARG F C     1 
ATOM   8100  O  O     . ARG E 2 116 ? 209.723 201.480 215.894 1.00 18.78  ? 185 ARG F O     1 
ATOM   8101  C  CB    . ARG E 2 116 ? 209.125 198.211 215.921 1.00 25.64  ? 185 ARG F CB    1 
ATOM   8102  C  CG    . ARG E 2 116 ? 210.428 198.298 215.146 1.00 30.17  ? 185 ARG F CG    1 
ATOM   8103  C  CD    . ARG E 2 116 ? 210.700 197.016 214.354 1.00 34.16  ? 185 ARG F CD    1 
ATOM   8104  N  NE    . ARG E 2 116 ? 212.032 197.061 213.738 1.00 36.54  ? 185 ARG F NE    1 
ATOM   8105  C  CZ    . ARG E 2 116 ? 212.351 197.724 212.631 1.00 42.48  ? 185 ARG F CZ    1 
ATOM   8106  N  NH1   . ARG E 2 116 ? 211.423 198.277 211.859 1.00 45.07  ? 185 ARG F NH1   1 
ATOM   8107  N  NH2   . ARG E 2 116 ? 213.615 197.779 212.250 1.00 47.09  ? 185 ARG F NH2   1 
ATOM   8108  N  N     . ASN E 2 117 ? 207.636 200.924 215.279 1.00 18.92  ? 186 ASN F N     1 
ATOM   8109  C  CA    . ASN E 2 117 ? 207.484 202.074 214.410 1.00 19.24  ? 186 ASN F CA    1 
ATOM   8110  C  C     . ASN E 2 117 ? 207.524 203.373 215.219 1.00 17.36  ? 186 ASN F C     1 
ATOM   8111  O  O     . ASN E 2 117 ? 208.114 204.361 214.787 1.00 15.90  ? 186 ASN F O     1 
ATOM   8112  C  CB    . ASN E 2 117 ? 206.197 201.987 213.598 1.00 21.85  ? 186 ASN F CB    1 
ATOM   8113  C  CG    . ASN E 2 117 ? 206.254 200.924 212.529 1.00 25.84  ? 186 ASN F CG    1 
ATOM   8114  O  OD1   . ASN E 2 117 ? 207.319 200.372 212.235 1.00 27.88  ? 186 ASN F OD1   1 
ATOM   8115  N  ND2   . ASN E 2 117 ? 205.111 200.628 211.932 1.00 29.82  ? 186 ASN F ND2   1 
ATOM   8116  N  N     . MET E 2 118 ? 206.873 203.382 216.381 1.00 16.47  ? 187 MET F N     1 
ATOM   8117  C  CA    . MET E 2 118 ? 206.874 204.560 217.233 1.00 17.39  ? 187 MET F CA    1 
ATOM   8118  C  C     . MET E 2 118 ? 208.293 204.888 217.703 1.00 16.91  ? 187 MET F C     1 
ATOM   8119  O  O     . MET E 2 118 ? 208.669 206.058 217.767 1.00 16.55  ? 187 MET F O     1 
ATOM   8120  C  CB    . MET E 2 118 ? 205.953 204.365 218.442 1.00 19.08  ? 187 MET F CB    1 
ATOM   8121  C  CG    . MET E 2 118 ? 204.481 204.451 218.104 1.00 22.76  ? 187 MET F CG    1 
ATOM   8122  S  SD    . MET E 2 118 ? 203.445 203.793 219.427 1.00 27.72  ? 187 MET F SD    1 
ATOM   8123  C  CE    . MET E 2 118 ? 201.931 203.454 218.522 1.00 31.23  ? 187 MET F CE    1 
ATOM   8124  N  N     . ASP E 2 119 ? 209.082 203.862 218.037 1.00 16.83  ? 188 ASP F N     1 
ATOM   8125  C  CA    . ASP E 2 119 ? 210.465 204.068 218.426 1.00 18.30  ? 188 ASP F CA    1 
ATOM   8126  C  C     . ASP E 2 119 ? 211.274 204.690 217.292 1.00 16.97  ? 188 ASP F C     1 
ATOM   8127  O  O     . ASP E 2 119 ? 212.087 205.581 217.528 1.00 16.01  ? 188 ASP F O     1 
ATOM   8128  C  CB    . ASP E 2 119 ? 211.104 202.778 218.892 1.00 21.53  ? 188 ASP F CB    1 
ATOM   8129  C  CG    . ASP E 2 119 ? 210.567 202.278 220.220 1.00 26.48  ? 188 ASP F CG    1 
ATOM   8130  O  OD1   . ASP E 2 119 ? 209.798 203.036 220.855 1.00 31.19  ? 188 ASP F OD1   1 
ATOM   8131  O  OD2   . ASP E 2 119 ? 210.891 201.123 220.594 1.00 31.99  ? 188 ASP F OD2   1 
ATOM   8132  N  N     . ILE E 2 120 ? 211.049 204.229 216.059 1.00 15.88  ? 189 ILE F N     1 
ATOM   8133  C  CA    . ILE E 2 120 ? 211.759 204.779 214.919 1.00 15.62  ? 189 ILE F CA    1 
ATOM   8134  C  C     . ILE E 2 120 ? 211.366 206.240 214.717 1.00 13.88  ? 189 ILE F C     1 
ATOM   8135  O  O     . ILE E 2 120 ? 212.226 207.085 214.457 1.00 13.30  ? 189 ILE F O     1 
ATOM   8136  C  CB    . ILE E 2 120 ? 211.496 203.939 213.653 1.00 17.24  ? 189 ILE F CB    1 
ATOM   8137  C  CG1   . ILE E 2 120 ? 211.953 202.498 213.835 1.00 18.83  ? 189 ILE F CG1   1 
ATOM   8138  C  CG2   . ILE E 2 120 ? 212.127 204.582 212.412 1.00 16.39  ? 189 ILE F CG2   1 
ATOM   8139  C  CD1   . ILE E 2 120 ? 213.369 202.366 214.336 1.00 21.61  ? 189 ILE F CD1   1 
ATOM   8140  N  N     . ALA E 2 121 ? 210.062 206.536 214.807 1.00 13.42  ? 190 ALA F N     1 
ATOM   8141  C  CA    . ALA E 2 121 ? 209.577 207.890 214.595 1.00 13.28  ? 190 ALA F CA    1 
ATOM   8142  C  C     . ALA E 2 121 ? 210.180 208.848 215.631 1.00 12.72  ? 190 ALA F C     1 
ATOM   8143  O  O     . ALA E 2 121 ? 210.557 209.966 215.303 1.00 12.79  ? 190 ALA F O     1 
ATOM   8144  C  CB    . ALA E 2 121 ? 208.067 207.924 214.619 1.00 13.05  ? 190 ALA F CB    1 
ATOM   8145  N  N     . MET E 2 122 ? 210.274 208.407 216.881 1.00 13.25  ? 191 MET F N     1 
ATOM   8146  C  CA    . MET E 2 122 ? 210.884 209.226 217.917 1.00 14.40  ? 191 MET F CA    1 
ATOM   8147  C  C     . MET E 2 122 ? 212.361 209.490 217.611 1.00 13.41  ? 191 MET F C     1 
ATOM   8148  O  O     . MET E 2 122 ? 212.854 210.582 217.864 1.00 13.51  ? 191 MET F O     1 
ATOM   8149  C  CB    . MET E 2 122 ? 210.743 208.563 219.289 1.00 15.39  ? 191 MET F CB    1 
ATOM   8150  C  CG    . MET E 2 122 ? 209.361 208.705 219.874 1.00 18.77  ? 191 MET F CG    1 
ATOM   8151  S  SD    . MET E 2 122 ? 209.281 207.987 221.526 1.00 22.75  ? 191 MET F SD    1 
ATOM   8152  C  CE    . MET E 2 122 ? 208.183 206.592 221.253 1.00 26.54  ? 191 MET F CE    1 
ATOM   8153  N  N     . GLY E 2 123 ? 213.071 208.490 217.080 1.00 12.45  ? 192 GLY F N     1 
ATOM   8154  C  CA    . GLY E 2 123 ? 214.479 208.647 216.755 1.00 12.57  ? 192 GLY F CA    1 
ATOM   8155  C  C     . GLY E 2 123 ? 214.697 209.728 215.697 1.00 11.98  ? 192 GLY F C     1 
ATOM   8156  O  O     . GLY E 2 123 ? 215.606 210.544 215.812 1.00 11.84  ? 192 GLY F O     1 
ATOM   8157  N  N     . TRP E 2 124 ? 213.863 209.723 214.659 1.00 11.77  ? 193 TRP F N     1 
ATOM   8158  C  CA    . TRP E 2 124 ? 213.943 210.757 213.644 1.00 12.10  ? 193 TRP F CA    1 
ATOM   8159  C  C     . TRP E 2 124 ? 213.698 212.140 214.243 1.00 11.70  ? 193 TRP F C     1 
ATOM   8160  O  O     . TRP E 2 124 ? 214.397 213.094 213.917 1.00 11.19  ? 193 TRP F O     1 
ATOM   8161  C  CB    . TRP E 2 124 ? 212.950 210.489 212.517 1.00 12.39  ? 193 TRP F CB    1 
ATOM   8162  C  CG    . TRP E 2 124 ? 213.354 209.373 211.605 1.00 12.63  ? 193 TRP F CG    1 
ATOM   8163  C  CD1   . TRP E 2 124 ? 212.876 208.098 211.615 1.00 13.03  ? 193 TRP F CD1   1 
ATOM   8164  C  CD2   . TRP E 2 124 ? 214.311 209.446 210.533 1.00 12.75  ? 193 TRP F CD2   1 
ATOM   8165  N  NE1   . TRP E 2 124 ? 213.465 207.373 210.616 1.00 13.26  ? 193 TRP F NE1   1 
ATOM   8166  C  CE2   . TRP E 2 124 ? 214.347 208.165 209.937 1.00 12.96  ? 193 TRP F CE2   1 
ATOM   8167  C  CE3   . TRP E 2 124 ? 215.128 210.459 210.023 1.00 12.80  ? 193 TRP F CE3   1 
ATOM   8168  C  CZ2   . TRP E 2 124 ? 215.162 207.879 208.847 1.00 13.04  ? 193 TRP F CZ2   1 
ATOM   8169  C  CZ3   . TRP E 2 124 ? 215.948 210.172 208.952 1.00 13.06  ? 193 TRP F CZ3   1 
ATOM   8170  C  CH2   . TRP E 2 124 ? 215.943 208.904 208.359 1.00 13.22  ? 193 TRP F CH2   1 
ATOM   8171  N  N     . LYS E 2 125 ? 212.696 212.259 215.114 1.00 12.70  ? 194 LYS F N     1 
ATOM   8172  C  CA    . LYS E 2 125 ? 212.448 213.521 215.788 1.00 13.27  ? 194 LYS F CA    1 
ATOM   8173  C  C     . LYS E 2 125 ? 213.613 213.881 216.713 1.00 12.26  ? 194 LYS F C     1 
ATOM   8174  O  O     . LYS E 2 125 ? 213.986 215.047 216.815 1.00 13.05  ? 194 LYS F O     1 
ATOM   8175  C  CB    . LYS E 2 125 ? 211.142 213.453 216.582 1.00 15.20  ? 194 LYS F CB    1 
ATOM   8176  C  CG    . LYS E 2 125 ? 209.924 213.381 215.690 1.00 17.45  ? 194 LYS F CG    1 
ATOM   8177  C  CD    . LYS E 2 125 ? 208.634 213.283 216.493 1.00 18.99  ? 194 LYS F CD    1 
ATOM   8178  C  CE    . LYS E 2 125 ? 208.265 214.557 217.200 1.00 20.19  ? 194 LYS F CE    1 
ATOM   8179  N  NZ    . LYS E 2 125 ? 207.597 215.496 216.297 1.00 20.48  ? 194 LYS F NZ    1 
ATOM   8180  N  N     . GLY E 2 126 ? 214.176 212.880 217.390 1.00 11.72  ? 195 GLY F N     1 
ATOM   8181  C  CA    . GLY E 2 126 ? 215.336 213.104 218.239 1.00 11.98  ? 195 GLY F CA    1 
ATOM   8182  C  C     . GLY E 2 126 ? 216.535 213.597 217.439 1.00 12.14  ? 195 GLY F C     1 
ATOM   8183  O  O     . GLY E 2 126 ? 217.243 214.500 217.875 1.00 12.64  ? 195 GLY F O     1 
ATOM   8184  N  N     . ALA E 2 127 ? 216.775 212.992 216.269 1.00 12.42  ? 196 ALA F N     1 
ATOM   8185  C  CA    . ALA E 2 127 ? 217.870 213.415 215.409 1.00 12.78  ? 196 ALA F CA    1 
ATOM   8186  C  C     . ALA E 2 127 ? 217.676 214.864 214.977 1.00 13.28  ? 196 ALA F C     1 
ATOM   8187  O  O     . ALA E 2 127 ? 218.638 215.638 214.956 1.00 14.01  ? 196 ALA F O     1 
ATOM   8188  C  CB    . ALA E 2 127 ? 218.003 212.495 214.219 1.00 13.37  ? 196 ALA F CB    1 
ATOM   8189  N  N     . GLN E 2 128 ? 216.442 215.226 214.617 1.00 13.03  ? 197 GLN F N     1 
ATOM   8190  C  CA    . GLN E 2 128 ? 216.140 216.596 214.246 1.00 14.15  ? 197 GLN F CA    1 
ATOM   8191  C  C     . GLN E 2 128 ? 216.344 217.532 215.442 1.00 13.92  ? 197 GLN F C     1 
ATOM   8192  O  O     . GLN E 2 128 ? 216.848 218.639 215.287 1.00 13.85  ? 197 GLN F O     1 
ATOM   8193  C  CB    . GLN E 2 128 ? 214.713 216.677 213.716 1.00 14.82  ? 197 GLN F CB    1 
ATOM   8194  C  CG    . GLN E 2 128 ? 214.328 218.032 213.138 1.00 16.01  ? 197 GLN F CG    1 
ATOM   8195  C  CD    . GLN E 2 128 ? 212.902 218.035 212.635 1.00 17.31  ? 197 GLN F CD    1 
ATOM   8196  O  OE1   . GLN E 2 128 ? 212.459 217.090 211.967 1.00 18.39  ? 197 GLN F OE1   1 
ATOM   8197  N  NE2   . GLN E 2 128 ? 212.162 219.079 212.973 1.00 18.11  ? 197 GLN F NE2   1 
ATOM   8198  N  N     . ALA E 2 129 ? 215.956 217.091 216.639 1.00 13.45  ? 198 ALA F N     1 
ATOM   8199  C  CA    . ALA E 2 129 ? 216.086 217.917 217.829 1.00 13.78  ? 198 ALA F CA    1 
ATOM   8200  C  C     . ALA E 2 129 ? 217.553 218.192 218.169 1.00 14.08  ? 198 ALA F C     1 
ATOM   8201  O  O     . ALA E 2 129 ? 217.893 219.281 218.620 1.00 14.39  ? 198 ALA F O     1 
ATOM   8202  C  CB    . ALA E 2 129 ? 215.389 217.260 218.997 1.00 13.73  ? 198 ALA F CB    1 
ATOM   8203  N  N     . MET E 2 130 ? 218.443 217.225 217.951 1.00 15.08  ? 199 MET F N     1 
ATOM   8204  C  CA    . MET E 2 130 ? 219.848 217.441 218.266 1.00 15.96  ? 199 MET F CA    1 
ATOM   8205  C  C     . MET E 2 130 ? 220.485 218.473 217.331 1.00 16.37  ? 199 MET F C     1 
ATOM   8206  O  O     . MET E 2 130 ? 221.536 219.014 217.662 1.00 18.57  ? 199 MET F O     1 
ATOM   8207  C  CB    . MET E 2 130 ? 220.633 216.134 218.187 1.00 16.50  ? 199 MET F CB    1 
ATOM   8208  C  CG    . MET E 2 130 ? 220.226 215.133 219.239 1.00 18.44  ? 199 MET F CG    1 
ATOM   8209  S  SD    . MET E 2 130 ? 221.396 213.770 219.304 1.00 22.04  ? 199 MET F SD    1 
ATOM   8210  C  CE    . MET E 2 130 ? 222.843 214.540 220.017 1.00 22.60  ? 199 MET F CE    1 
ATOM   8211  N  N     . GLN E 2 131 ? 219.868 218.743 216.176 1.00 16.63  ? 200 GLN F N     1 
ATOM   8212  C  CA    . GLN E 2 131 ? 220.395 219.721 215.233 1.00 17.42  ? 200 GLN F CA    1 
ATOM   8213  C  C     . GLN E 2 131 ? 219.693 221.079 215.347 1.00 16.12  ? 200 GLN F C     1 
ATOM   8214  O  O     . GLN E 2 131 ? 220.330 222.102 215.130 1.00 18.12  ? 200 GLN F O     1 
ATOM   8215  C  CB    . GLN E 2 131 ? 220.228 219.224 213.796 1.00 18.23  ? 200 GLN F CB    1 
ATOM   8216  C  CG    . GLN E 2 131 ? 220.904 217.888 213.533 1.00 20.49  ? 200 GLN F CG    1 
ATOM   8217  C  CD    . GLN E 2 131 ? 220.528 217.307 212.191 1.00 23.83  ? 200 GLN F CD    1 
ATOM   8218  O  OE1   . GLN E 2 131 ? 219.868 216.263 212.103 1.00 25.50  ? 200 GLN F OE1   1 
ATOM   8219  N  NE2   . GLN E 2 131 ? 220.931 217.999 211.132 1.00 26.07  ? 200 GLN F NE2   1 
ATOM   8220  N  N     . PHE E 2 132 ? 218.394 221.100 215.668 1.00 15.30  ? 201 PHE F N     1 
ATOM   8221  C  CA    . PHE E 2 132 ? 217.639 222.344 215.654 1.00 15.94  ? 201 PHE F CA    1 
ATOM   8222  C  C     . PHE E 2 132 ? 216.854 222.594 216.942 1.00 15.44  ? 201 PHE F C     1 
ATOM   8223  O  O     . PHE E 2 132 ? 216.262 223.659 217.074 1.00 16.29  ? 201 PHE F O     1 
ATOM   8224  C  CB    . PHE E 2 132 ? 216.632 222.370 214.504 1.00 16.28  ? 201 PHE F CB    1 
ATOM   8225  C  CG    . PHE E 2 132 ? 217.278 222.094 213.162 1.00 17.50  ? 201 PHE F CG    1 
ATOM   8226  C  CD1   . PHE E 2 132 ? 218.082 223.052 212.561 1.00 18.05  ? 201 PHE F CD1   1 
ATOM   8227  C  CD2   . PHE E 2 132 ? 217.083 220.880 212.520 1.00 17.73  ? 201 PHE F CD2   1 
ATOM   8228  C  CE1   . PHE E 2 132 ? 218.678 222.795 211.334 1.00 18.34  ? 201 PHE F CE1   1 
ATOM   8229  C  CE2   . PHE E 2 132 ? 217.670 220.637 211.286 1.00 18.20  ? 201 PHE F CE2   1 
ATOM   8230  C  CZ    . PHE E 2 132 ? 218.470 221.589 210.703 1.00 17.68  ? 201 PHE F CZ    1 
ATOM   8231  N  N     . GLY E 2 133 ? 216.821 221.636 217.869 1.00 14.22  ? 202 GLY F N     1 
ATOM   8232  C  CA    . GLY E 2 133 ? 215.996 221.798 219.055 1.00 13.75  ? 202 GLY F CA    1 
ATOM   8233  C  C     . GLY E 2 133 ? 216.591 222.817 220.020 1.00 12.75  ? 202 GLY F C     1 
ATOM   8234  O  O     . GLY E 2 133 ? 217.783 223.102 219.992 1.00 13.08  ? 202 GLY F O     1 
ATOM   8235  N  N     . GLN E 2 134 ? 215.740 223.333 220.898 1.00 12.15  ? 203 GLN F N     1 
ATOM   8236  C  CA    . GLN E 2 134 ? 216.187 224.222 221.951 1.00 12.35  ? 203 GLN F CA    1 
ATOM   8237  C  C     . GLN E 2 134 ? 216.961 223.406 222.983 1.00 12.33  ? 203 GLN F C     1 
ATOM   8238  O  O     . GLN E 2 134 ? 216.491 222.371 223.441 1.00 11.81  ? 203 GLN F O     1 
ATOM   8239  C  CB    . GLN E 2 134 ? 214.993 224.912 222.595 1.00 12.59  ? 203 GLN F CB    1 
ATOM   8240  C  CG    . GLN E 2 134 ? 215.377 225.953 223.642 1.00 13.24  ? 203 GLN F CG    1 
ATOM   8241  C  CD    . GLN E 2 134 ? 214.177 226.577 224.308 1.00 13.79  ? 203 GLN F CD    1 
ATOM   8242  O  OE1   . GLN E 2 134 ? 213.034 226.245 223.986 1.00 14.31  ? 203 GLN F OE1   1 
ATOM   8243  N  NE2   . GLN E 2 134 ? 214.421 227.485 225.240 1.00 14.15  ? 203 GLN F NE2   1 
ATOM   8244  N  N     . PRO E 2 135 ? 218.161 223.849 223.396 1.00 12.43  ? 204 PRO F N     1 
ATOM   8245  C  CA    . PRO E 2 135 ? 218.914 223.120 224.407 1.00 12.75  ? 204 PRO F CA    1 
ATOM   8246  C  C     . PRO E 2 135 ? 218.242 223.196 225.771 1.00 11.99  ? 204 PRO F C     1 
ATOM   8247  O  O     . PRO E 2 135 ? 217.750 224.246 226.175 1.00 13.34  ? 204 PRO F O     1 
ATOM   8248  C  CB    . PRO E 2 135 ? 220.286 223.801 224.422 1.00 12.97  ? 204 PRO F CB    1 
ATOM   8249  C  CG    . PRO E 2 135 ? 220.300 224.656 223.192 1.00 13.47  ? 204 PRO F CG    1 
ATOM   8250  C  CD    . PRO E 2 135 ? 218.864 225.051 222.926 1.00 12.84  ? 204 PRO F CD    1 
ATOM   8251  N  N     . LEU E 2 136 ? 218.253 222.067 226.474 1.00 11.27  ? 205 LEU F N     1 
ATOM   8252  C  CA    . LEU E 2 136 ? 217.873 222.001 227.869 1.00 11.48  ? 205 LEU F CA    1 
ATOM   8253  C  C     . LEU E 2 136 ? 218.973 221.241 228.597 1.00 11.25  ? 205 LEU F C     1 
ATOM   8254  O  O     . LEU E 2 136 ? 219.314 220.116 228.226 1.00 11.12  ? 205 LEU F O     1 
ATOM   8255  C  CB    . LEU E 2 136 ? 216.510 221.333 228.047 1.00 11.80  ? 205 LEU F CB    1 
ATOM   8256  C  CG    . LEU E 2 136 ? 216.046 221.155 229.493 1.00 12.62  ? 205 LEU F CG    1 
ATOM   8257  C  CD1   . LEU E 2 136 ? 215.709 222.483 230.107 1.00 12.48  ? 205 LEU F CD1   1 
ATOM   8258  C  CD2   . LEU E 2 136 ? 214.854 220.237 229.597 1.00 12.72  ? 205 LEU F CD2   1 
ATOM   8259  N  N     . VAL E 2 137 ? 219.490 221.853 229.668 1.00 11.17  ? 206 VAL F N     1 
ATOM   8260  C  CA    . VAL E 2 137 ? 220.657 221.334 230.346 1.00 12.02  ? 206 VAL F CA    1 
ATOM   8261  C  C     . VAL E 2 137 ? 220.241 220.726 231.678 1.00 12.58  ? 206 VAL F C     1 
ATOM   8262  O  O     . VAL E 2 137 ? 219.597 221.392 232.485 1.00 12.30  ? 206 VAL F O     1 
ATOM   8263  C  CB    . VAL E 2 137 ? 221.713 222.435 230.562 1.00 12.22  ? 206 VAL F CB    1 
ATOM   8264  C  CG1   . VAL E 2 137 ? 222.850 221.955 231.439 1.00 12.13  ? 206 VAL F CG1   1 
ATOM   8265  C  CG2   . VAL E 2 137 ? 222.264 222.934 229.241 1.00 12.19  ? 206 VAL F CG2   1 
ATOM   8266  N  N     . PHE E 2 138 ? 220.649 219.474 231.892 1.00 12.89  ? 207 PHE F N     1 
ATOM   8267  C  CA    . PHE E 2 138 ? 220.592 218.854 233.200 1.00 13.99  ? 207 PHE F CA    1 
ATOM   8268  C  C     . PHE E 2 138 ? 221.994 218.899 233.794 1.00 14.96  ? 207 PHE F C     1 
ATOM   8269  O  O     . PHE E 2 138 ? 222.896 218.205 233.320 1.00 14.71  ? 207 PHE F O     1 
ATOM   8270  C  CB    . PHE E 2 138 ? 220.072 217.420 233.111 1.00 14.54  ? 207 PHE F CB    1 
ATOM   8271  C  CG    . PHE E 2 138 ? 218.588 217.330 232.817 1.00 16.80  ? 207 PHE F CG    1 
ATOM   8272  C  CD1   . PHE E 2 138 ? 218.126 217.389 231.508 1.00 17.31  ? 207 PHE F CD1   1 
ATOM   8273  C  CD2   . PHE E 2 138 ? 217.666 217.206 233.848 1.00 17.96  ? 207 PHE F CD2   1 
ATOM   8274  C  CE1   . PHE E 2 138 ? 216.772 217.322 231.232 1.00 18.17  ? 207 PHE F CE1   1 
ATOM   8275  C  CE2   . PHE E 2 138 ? 216.316 217.124 233.571 1.00 18.05  ? 207 PHE F CE2   1 
ATOM   8276  C  CZ    . PHE E 2 138 ? 215.867 217.179 232.261 1.00 18.15  ? 207 PHE F CZ    1 
ATOM   8277  N  N     . ASP E 2 139 ? 222.166 219.717 234.835 1.00 15.30  ? 208 ASP F N     1 
ATOM   8278  C  CA    . ASP E 2 139 ? 223.472 219.917 235.430 1.00 16.69  ? 208 ASP F CA    1 
ATOM   8279  C  C     . ASP E 2 139 ? 223.773 218.779 236.404 1.00 17.28  ? 208 ASP F C     1 
ATOM   8280  O  O     . ASP E 2 139 ? 223.104 218.648 237.426 1.00 18.25  ? 208 ASP F O     1 
ATOM   8281  C  CB    . ASP E 2 139 ? 223.537 221.270 236.111 1.00 18.29  ? 208 ASP F CB    1 
ATOM   8282  C  CG    . ASP E 2 139 ? 224.912 221.641 236.640 1.00 19.88  ? 208 ASP F CG    1 
ATOM   8283  O  OD1   . ASP E 2 139 ? 225.873 220.928 236.302 1.00 22.52  ? 208 ASP F OD1   1 
ATOM   8284  O  OD2   . ASP E 2 139 ? 225.015 222.636 237.379 1.00 22.46  ? 208 ASP F OD2   1 
ATOM   8285  N  N     . MET E 2 140 ? 224.788 217.972 236.088 1.00 17.99  ? 209 MET F N     1 
ATOM   8286  C  CA    . MET E 2 140 ? 225.122 216.795 236.873 1.00 20.08  ? 209 MET F CA    1 
ATOM   8287  C  C     . MET E 2 140 ? 226.254 217.072 237.866 1.00 21.71  ? 209 MET F C     1 
ATOM   8288  O  O     . MET E 2 140 ? 226.996 216.158 238.213 1.00 22.38  ? 209 MET F O     1 
ATOM   8289  C  CB    . MET E 2 140 ? 225.546 215.645 235.953 1.00 21.43  ? 209 MET F CB    1 
ATOM   8290  C  CG    . MET E 2 140 ? 224.618 215.428 234.778 1.00 22.53  ? 209 MET F CG    1 
ATOM   8291  S  SD    . MET E 2 140 ? 223.006 214.898 235.372 1.00 25.59  ? 209 MET F SD    1 
ATOM   8292  C  CE    . MET E 2 140 ? 222.311 214.163 233.890 1.00 24.78  ? 209 MET F CE    1 
ATOM   8293  N  N     . ALA E 2 141 ? 226.364 218.313 238.346 1.00 22.68  ? 210 ALA F N     1 
ATOM   8294  C  CA    . ALA E 2 141 ? 227.438 218.699 239.250 1.00 24.87  ? 210 ALA F CA    1 
ATOM   8295  C  C     . ALA E 2 141 ? 227.041 218.556 240.720 1.00 27.41  ? 210 ALA F C     1 
ATOM   8296  O  O     . ALA E 2 141 ? 227.571 219.280 241.559 1.00 29.53  ? 210 ALA F O     1 
ATOM   8297  C  CB    . ALA E 2 141 ? 227.835 220.130 238.960 1.00 24.77  ? 210 ALA F CB    1 
ATOM   8298  N  N     . TYR E 2 142 ? 226.131 217.628 241.050 1.00 28.25  ? 211 TYR F N     1 
ATOM   8299  C  CA    . TYR E 2 142 ? 225.611 217.521 242.407 1.00 27.79  ? 211 TYR F CA    1 
ATOM   8300  C  C     . TYR E 2 142 ? 225.913 216.165 243.038 1.00 28.47  ? 211 TYR F C     1 
ATOM   8301  O  O     . TYR E 2 142 ? 225.249 215.777 243.995 1.00 29.76  ? 211 TYR F O     1 
ATOM   8302  C  CB    . TYR E 2 142 ? 224.096 217.741 242.401 1.00 27.76  ? 211 TYR F CB    1 
ATOM   8303  C  CG    . TYR E 2 142 ? 223.714 219.153 242.005 1.00 28.54  ? 211 TYR F CG    1 
ATOM   8304  C  CD1   . TYR E 2 142 ? 223.522 219.493 240.674 1.00 28.66  ? 211 TYR F CD1   1 
ATOM   8305  C  CD2   . TYR E 2 142 ? 223.541 220.135 242.968 1.00 28.35  ? 211 TYR F CD2   1 
ATOM   8306  C  CE1   . TYR E 2 142 ? 223.169 220.780 240.310 1.00 28.68  ? 211 TYR F CE1   1 
ATOM   8307  C  CE2   . TYR E 2 142 ? 223.183 221.423 242.618 1.00 29.99  ? 211 TYR F CE2   1 
ATOM   8308  C  CZ    . TYR E 2 142 ? 222.997 221.743 241.285 1.00 30.09  ? 211 TYR F CZ    1 
ATOM   8309  O  OH    . TYR E 2 142 ? 222.659 223.012 240.940 1.00 29.60  ? 211 TYR F OH    1 
ATOM   8310  N  N     . GLU E 2 143 ? 226.901 215.435 242.517 1.00 31.49  ? 212 GLU F N     1 
ATOM   8311  C  CA    . GLU E 2 143 ? 227.196 214.107 243.035 1.00 36.08  ? 212 GLU F CA    1 
ATOM   8312  C  C     . GLU E 2 143 ? 227.702 214.193 244.477 1.00 38.42  ? 212 GLU F C     1 
ATOM   8313  O  O     . GLU E 2 143 ? 227.398 213.333 245.297 1.00 39.40  ? 212 GLU F O     1 
ATOM   8314  C  CB    . GLU E 2 143 ? 228.217 213.399 242.149 1.00 40.26  ? 212 GLU F CB    1 
ATOM   8315  C  CG    . GLU E 2 143 ? 227.736 213.196 240.715 1.00 43.17  ? 212 GLU F CG    1 
ATOM   8316  C  CD    . GLU E 2 143 ? 228.648 212.280 239.920 1.00 46.72  ? 212 GLU F CD    1 
ATOM   8317  O  OE1   . GLU E 2 143 ? 228.718 211.096 240.286 1.00 50.17  ? 212 GLU F OE1   1 
ATOM   8318  O  OE2   . GLU E 2 143 ? 229.301 212.731 238.956 1.00 51.60  ? 212 GLU F OE2   1 
ATOM   8319  N  N     . ASN E 2 144 ? 228.458 215.247 244.792 1.00 40.09  ? 213 ASN F N     1 
ATOM   8320  C  CA    . ASN E 2 144 ? 229.060 215.408 246.108 1.00 42.36  ? 213 ASN F CA    1 
ATOM   8321  C  C     . ASN E 2 144 ? 228.014 215.679 247.187 1.00 39.27  ? 213 ASN F C     1 
ATOM   8322  O  O     . ASN E 2 144 ? 228.259 215.385 248.354 1.00 44.67  ? 213 ASN F O     1 
ATOM   8323  C  CB    . ASN E 2 144 ? 230.099 216.526 246.107 1.00 45.66  ? 213 ASN F CB    1 
ATOM   8324  C  CG    . ASN E 2 144 ? 231.349 216.152 245.344 1.00 51.43  ? 213 ASN F CG    1 
ATOM   8325  O  OD1   . ASN E 2 144 ? 231.580 214.972 245.049 1.00 52.07  ? 213 ASN F OD1   1 
ATOM   8326  N  ND2   . ASN E 2 144 ? 232.182 217.137 245.035 1.00 55.83  ? 213 ASN F ND2   1 
ATOM   8327  N  N     . TYR E 2 145 ? 226.856 216.224 246.811 1.00 36.71  ? 214 TYR F N     1 
ATOM   8328  C  CA    . TYR E 2 145 ? 225.835 216.600 247.778 1.00 36.57  ? 214 TYR F CA    1 
ATOM   8329  C  C     . TYR E 2 145 ? 224.794 215.499 247.985 1.00 33.82  ? 214 TYR F C     1 
ATOM   8330  O  O     . TYR E 2 145 ? 223.864 215.696 248.761 1.00 35.83  ? 214 TYR F O     1 
ATOM   8331  C  CB    . TYR E 2 145 ? 225.107 217.865 247.315 1.00 37.58  ? 214 TYR F CB    1 
ATOM   8332  C  CG    . TYR E 2 145 ? 226.003 219.072 247.091 1.00 41.43  ? 214 TYR F CG    1 
ATOM   8333  C  CD1   . TYR E 2 145 ? 226.666 219.258 245.888 1.00 42.94  ? 214 TYR F CD1   1 
ATOM   8334  C  CD2   . TYR E 2 145 ? 226.184 220.020 248.087 1.00 44.86  ? 214 TYR F CD2   1 
ATOM   8335  C  CE1   . TYR E 2 145 ? 227.481 220.358 245.679 1.00 45.72  ? 214 TYR F CE1   1 
ATOM   8336  C  CE2   . TYR E 2 145 ? 226.998 221.123 247.892 1.00 47.44  ? 214 TYR F CE2   1 
ATOM   8337  C  CZ    . TYR E 2 145 ? 227.650 221.292 246.685 1.00 47.62  ? 214 TYR F CZ    1 
ATOM   8338  O  OH    . TYR E 2 145 ? 228.455 222.378 246.498 1.00 49.93  ? 214 TYR F OH    1 
ATOM   8339  N  N     . MET E 2 146 ? 224.938 214.351 247.313 1.00 31.23  ? 215 MET F N     1 
ATOM   8340  C  CA    . MET E 2 146 ? 223.911 213.319 247.340 1.00 30.66  ? 215 MET F CA    1 
ATOM   8341  C  C     . MET E 2 146 ? 224.484 212.021 247.904 1.00 30.39  ? 215 MET F C     1 
ATOM   8342  O  O     . MET E 2 146 ? 225.607 211.641 247.591 1.00 33.08  ? 215 MET F O     1 
ATOM   8343  C  CB    . MET E 2 146 ? 223.350 213.070 245.932 1.00 28.86  ? 215 MET F CB    1 
ATOM   8344  C  CG    . MET E 2 146 ? 222.394 214.141 245.461 1.00 28.96  ? 215 MET F CG    1 
ATOM   8345  S  SD    . MET E 2 146 ? 221.436 213.634 244.018 1.00 25.82  ? 215 MET F SD    1 
ATOM   8346  C  CE    . MET E 2 146 ? 222.712 213.632 242.760 1.00 24.95  ? 215 MET F CE    1 
ATOM   8347  N  N     . LYS E 2 147 ? 223.677 211.332 248.712 1.00 33.10  ? 216 LYS F N     1 
ATOM   8348  C  CA    . LYS E 2 147 ? 224.014 210.002 249.189 1.00 37.68  ? 216 LYS F CA    1 
ATOM   8349  C  C     . LYS E 2 147 ? 223.640 208.966 248.128 1.00 37.65  ? 216 LYS F C     1 
ATOM   8350  O  O     . LYS E 2 147 ? 223.192 209.302 247.036 1.00 37.61  ? 216 LYS F O     1 
ATOM   8351  C  CB    . LYS E 2 147 ? 223.290 209.730 250.510 1.00 43.28  ? 216 LYS F CB    1 
ATOM   8352  C  CG    . LYS E 2 147 ? 223.477 210.814 251.555 1.00 48.96  ? 216 LYS F CG    1 
ATOM   8353  C  CD    . LYS E 2 147 ? 222.433 210.725 252.659 1.00 54.39  ? 216 LYS F CD    1 
ATOM   8354  C  CE    . LYS E 2 147 ? 222.523 211.845 253.648 1.00 59.73  ? 216 LYS F CE    1 
ATOM   8355  N  NZ    . LYS E 2 147 ? 221.362 211.891 254.544 1.00 61.40  ? 216 LYS F NZ    1 
ATOM   8356  N  N     . ARG E 2 148 ? 223.865 207.690 248.448 1.00 37.77  ? 217 ARG F N     1 
ATOM   8357  C  CA    . ARG E 2 148 ? 223.580 206.599 247.531 1.00 39.00  ? 217 ARG F CA    1 
ATOM   8358  C  C     . ARG E 2 148 ? 222.109 206.616 247.121 1.00 34.46  ? 217 ARG F C     1 
ATOM   8359  O  O     . ARG E 2 148 ? 221.786 206.553 245.940 1.00 32.18  ? 217 ARG F O     1 
ATOM   8360  C  CB    . ARG E 2 148 ? 223.966 205.271 248.192 1.00 45.99  ? 217 ARG F CB    1 
ATOM   8361  C  CG    . ARG E 2 148 ? 223.377 204.013 247.569 1.00 53.78  ? 217 ARG F CG    1 
ATOM   8362  C  CD    . ARG E 2 148 ? 223.625 203.895 246.085 1.00 61.14  ? 217 ARG F CD    1 
ATOM   8363  N  NE    . ARG E 2 148 ? 225.053 203.967 245.762 1.00 70.47  ? 217 ARG F NE    1 
ATOM   8364  C  CZ    . ARG E 2 148 ? 225.597 203.603 244.607 1.00 81.28  ? 217 ARG F CZ    1 
ATOM   8365  N  NH1   . ARG E 2 148 ? 224.869 203.015 243.672 1.00 80.90  ? 217 ARG F NH1   1 
ATOM   8366  N  NH2   . ARG E 2 148 ? 226.888 203.799 244.393 1.00 84.00  ? 217 ARG F NH2   1 
ATOM   8367  N  N     . LYS E 2 149 ? 221.215 206.675 248.105 1.00 31.72  ? 218 LYS F N     1 
ATOM   8368  C  CA    . LYS E 2 149 ? 219.782 206.637 247.856 1.00 31.45  ? 218 LYS F CA    1 
ATOM   8369  C  C     . LYS E 2 149 ? 219.338 207.797 246.960 1.00 29.93  ? 218 LYS F C     1 
ATOM   8370  O  O     . LYS E 2 149 ? 218.575 207.598 246.025 1.00 27.87  ? 218 LYS F O     1 
ATOM   8371  C  CB    . LYS E 2 149 ? 219.028 206.681 249.187 1.00 34.10  ? 218 LYS F CB    1 
ATOM   8372  C  CG    . LYS E 2 149 ? 217.539 206.837 249.024 1.00 39.44  ? 218 LYS F CG    1 
ATOM   8373  C  CD    . LYS E 2 149 ? 216.824 207.125 250.336 1.00 43.79  ? 218 LYS F CD    1 
ATOM   8374  C  CE    . LYS E 2 149 ? 215.448 207.648 250.079 1.00 46.25  ? 218 LYS F CE    1 
ATOM   8375  N  NZ    . LYS E 2 149 ? 214.800 208.165 251.291 1.00 50.28  ? 218 LYS F NZ    1 
ATOM   8376  N  N     . GLU E 2 150 ? 219.794 209.013 247.262 1.00 28.24  ? 219 GLU F N     1 
ATOM   8377  C  CA    . GLU E 2 150 ? 219.405 210.190 246.502 1.00 26.77  ? 219 GLU F CA    1 
ATOM   8378  C  C     . GLU E 2 150 ? 219.929 210.111 245.071 1.00 24.02  ? 219 GLU F C     1 
ATOM   8379  O  O     . GLU E 2 150 ? 219.248 210.511 244.140 1.00 23.26  ? 219 GLU F O     1 
ATOM   8380  C  CB    . GLU E 2 150 ? 219.919 211.452 247.192 1.00 30.57  ? 219 GLU F CB    1 
ATOM   8381  C  CG    . GLU E 2 150 ? 219.119 211.836 248.435 1.00 34.24  ? 219 GLU F CG    1 
ATOM   8382  C  CD    . GLU E 2 150 ? 219.854 212.826 249.329 1.00 41.01  ? 219 GLU F CD    1 
ATOM   8383  O  OE1   . GLU E 2 150 ? 221.083 213.009 249.182 1.00 40.61  ? 219 GLU F OE1   1 
ATOM   8384  O  OE2   . GLU E 2 150 ? 219.191 213.437 250.188 1.00 43.71  ? 219 GLU F OE2   1 
ATOM   8385  N  N     . LEU E 2 151 ? 221.145 209.602 244.887 1.00 24.65  ? 220 LEU F N     1 
ATOM   8386  C  CA    . LEU E 2 151 ? 221.722 209.481 243.557 1.00 24.99  ? 220 LEU F CA    1 
ATOM   8387  C  C     . LEU E 2 151 ? 220.936 208.470 242.717 1.00 24.00  ? 220 LEU F C     1 
ATOM   8388  O  O     . LEU E 2 151 ? 220.739 208.676 241.520 1.00 21.49  ? 220 LEU F O     1 
ATOM   8389  C  CB    . LEU E 2 151 ? 223.199 209.104 243.675 1.00 28.28  ? 220 LEU F CB    1 
ATOM   8390  C  CG    . LEU E 2 151 ? 224.024 209.162 242.383 1.00 32.21  ? 220 LEU F CG    1 
ATOM   8391  C  CD1   . LEU E 2 151 ? 225.454 209.564 242.669 1.00 36.08  ? 220 LEU F CD1   1 
ATOM   8392  C  CD2   . LEU E 2 151 ? 223.986 207.831 241.643 1.00 33.86  ? 220 LEU F CD2   1 
ATOM   8393  N  N     . GLN E 2 152 ? 220.471 207.387 243.345 1.00 24.38  ? 221 GLN F N     1 
ATOM   8394  C  CA    . GLN E 2 152 ? 219.638 206.412 242.662 1.00 26.11  ? 221 GLN F CA    1 
ATOM   8395  C  C     . GLN E 2 152 ? 218.353 207.064 242.158 1.00 21.86  ? 221 GLN F C     1 
ATOM   8396  O  O     . GLN E 2 152 ? 217.946 206.835 241.023 1.00 20.62  ? 221 GLN F O     1 
ATOM   8397  C  CB    . GLN E 2 152 ? 219.287 205.262 243.602 1.00 31.03  ? 221 GLN F CB    1 
ATOM   8398  C  CG    . GLN E 2 152 ? 220.475 204.385 243.964 1.00 38.26  ? 221 GLN F CG    1 
ATOM   8399  C  CD    . GLN E 2 152 ? 220.984 203.624 242.769 1.00 45.43  ? 221 GLN F CD    1 
ATOM   8400  O  OE1   . GLN E 2 152 ? 222.190 203.543 242.515 1.00 50.36  ? 221 GLN F OE1   1 
ATOM   8401  N  NE2   . GLN E 2 152 ? 220.054 203.049 242.019 1.00 52.14  ? 221 GLN F NE2   1 
ATOM   8402  N  N     . ASN E 2 153 ? 217.695 207.849 243.007 1.00 18.66  ? 222 ASN F N     1 
ATOM   8403  C  CA    . ASN E 2 153 ? 216.440 208.472 242.635 1.00 18.61  ? 222 ASN F CA    1 
ATOM   8404  C  C     . ASN E 2 153 ? 216.656 209.534 241.560 1.00 16.48  ? 222 ASN F C     1 
ATOM   8405  O  O     . ASN E 2 153 ? 215.772 209.772 240.744 1.00 16.94  ? 222 ASN F O     1 
ATOM   8406  C  CB    . ASN E 2 153 ? 215.737 209.054 243.853 1.00 19.47  ? 222 ASN F CB    1 
ATOM   8407  C  CG    . ASN E 2 153 ? 214.301 209.421 243.556 1.00 21.83  ? 222 ASN F CG    1 
ATOM   8408  O  OD1   . ASN E 2 153 ? 213.951 210.606 243.562 1.00 24.10  ? 222 ASN F OD1   1 
ATOM   8409  N  ND2   . ASN E 2 153 ? 213.453 208.436 243.293 1.00 23.22  ? 222 ASN F ND2   1 
ATOM   8410  N  N     . THR E 2 154 ? 217.824 210.179 241.555 1.00 15.25  ? 223 THR F N     1 
ATOM   8411  C  CA    . THR E 2 154 ? 218.121 211.180 240.545 1.00 14.92  ? 223 THR F CA    1 
ATOM   8412  C  C     . THR E 2 154 ? 218.111 210.531 239.161 1.00 14.09  ? 223 THR F C     1 
ATOM   8413  O  O     . THR E 2 154 ? 217.599 211.096 238.204 1.00 14.17  ? 223 THR F O     1 
ATOM   8414  C  CB    . THR E 2 154 ? 219.462 211.863 240.825 1.00 14.74  ? 223 THR F CB    1 
ATOM   8415  O  OG1   . THR E 2 154 ? 219.402 212.501 242.097 1.00 15.17  ? 223 THR F OG1   1 
ATOM   8416  C  CG2   . THR E 2 154 ? 219.771 212.893 239.757 1.00 14.94  ? 223 THR F CG2   1 
ATOM   8417  N  N     . VAL E 2 155 ? 218.730 209.358 239.038 1.00 14.76  ? 224 VAL F N     1 
ATOM   8418  C  CA    . VAL E 2 155 ? 218.789 208.673 237.757 1.00 15.46  ? 224 VAL F CA    1 
ATOM   8419  C  C     . VAL E 2 155 ? 217.398 208.220 237.313 1.00 14.32  ? 224 VAL F C     1 
ATOM   8420  O  O     . VAL E 2 155 ? 217.082 208.311 236.128 1.00 14.15  ? 224 VAL F O     1 
ATOM   8421  C  CB    . VAL E 2 155 ? 219.779 207.501 237.832 1.00 17.24  ? 224 VAL F CB    1 
ATOM   8422  C  CG1   . VAL E 2 155 ? 219.663 206.583 236.622 1.00 17.72  ? 224 VAL F CG1   1 
ATOM   8423  C  CG2   . VAL E 2 155 ? 221.193 208.031 237.995 1.00 18.53  ? 224 VAL F CG2   1 
ATOM   8424  N  N     . SER E 2 156 ? 216.576 207.747 238.261 1.00 13.83  ? 225 SER F N     1 
ATOM   8425  C  CA    . SER E 2 156 ? 215.201 207.369 237.959 1.00 14.14  ? 225 SER F CA    1 
ATOM   8426  C  C     . SER E 2 156 ? 214.430 208.552 237.371 1.00 13.39  ? 225 SER F C     1 
ATOM   8427  O  O     . SER E 2 156 ? 213.708 208.403 236.388 1.00 13.73  ? 225 SER F O     1 
ATOM   8428  C  CB    . SER E 2 156 ? 214.491 206.820 239.173 1.00 14.71  ? 225 SER F CB    1 
ATOM   8429  O  OG    . SER E 2 156 ? 215.045 205.574 239.562 1.00 18.29  ? 225 SER F OG    1 
ATOM   8430  N  N     . GLN E 2 157 ? 214.571 209.728 237.991 1.00 12.56  ? 226 GLN F N     1 
ATOM   8431  C  CA    . GLN E 2 157 ? 213.906 210.921 237.506 1.00 12.62  ? 226 GLN F CA    1 
ATOM   8432  C  C     . GLN E 2 157 ? 214.453 211.330 236.140 1.00 11.90  ? 226 GLN F C     1 
ATOM   8433  O  O     . GLN E 2 157 ? 213.699 211.801 235.294 1.00 12.90  ? 226 GLN F O     1 
ATOM   8434  C  CB    . GLN E 2 157 ? 214.049 212.059 238.511 1.00 12.87  ? 226 GLN F CB    1 
ATOM   8435  C  CG    . GLN E 2 157 ? 213.358 211.779 239.840 1.00 13.37  ? 226 GLN F CG    1 
ATOM   8436  C  CD    . GLN E 2 157 ? 213.307 213.003 240.729 1.00 13.98  ? 226 GLN F CD    1 
ATOM   8437  O  OE1   . GLN E 2 157 ? 213.570 214.132 240.296 1.00 15.29  ? 226 GLN F OE1   1 
ATOM   8438  N  NE2   . GLN E 2 157 ? 212.957 212.792 241.985 1.00 13.65  ? 226 GLN F NE2   1 
ATOM   8439  N  N     . LEU E 2 158 ? 215.759 211.165 235.927 1.00 12.38  ? 227 LEU F N     1 
ATOM   8440  C  CA    . LEU E 2 158 ? 216.363 211.486 234.641 1.00 12.72  ? 227 LEU F CA    1 
ATOM   8441  C  C     . LEU E 2 158 ? 215.837 210.554 233.554 1.00 13.08  ? 227 LEU F C     1 
ATOM   8442  O  O     . LEU E 2 158 ? 215.606 210.996 232.431 1.00 13.35  ? 227 LEU F O     1 
ATOM   8443  C  CB    . LEU E 2 158 ? 217.880 211.415 234.731 1.00 13.16  ? 227 LEU F CB    1 
ATOM   8444  C  CG    . LEU E 2 158 ? 218.569 212.570 235.462 1.00 13.09  ? 227 LEU F CG    1 
ATOM   8445  C  CD1   . LEU E 2 158 ? 219.968 212.158 235.865 1.00 13.21  ? 227 LEU F CD1   1 
ATOM   8446  C  CD2   . LEU E 2 158 ? 218.588 213.809 234.592 1.00 12.94  ? 227 LEU F CD2   1 
ATOM   8447  N  N     . LEU E 2 159 ? 215.697 209.261 233.871 1.00 13.46  ? 228 LEU F N     1 
ATOM   8448  C  CA    . LEU E 2 159 ? 215.126 208.307 232.924 1.00 13.74  ? 228 LEU F CA    1 
ATOM   8449  C  C     . LEU E 2 159 ? 213.719 208.736 232.511 1.00 13.07  ? 228 LEU F C     1 
ATOM   8450  O  O     . LEU E 2 159 ? 213.383 208.719 231.326 1.00 13.06  ? 228 LEU F O     1 
ATOM   8451  C  CB    . LEU E 2 159 ? 215.111 206.897 233.509 1.00 15.18  ? 228 LEU F CB    1 
ATOM   8452  C  CG    . LEU E 2 159 ? 216.274 205.968 233.148 1.00 16.88  ? 228 LEU F CG    1 
ATOM   8453  C  CD1   . LEU E 2 159 ? 217.622 206.552 233.459 1.00 17.38  ? 228 LEU F CD1   1 
ATOM   8454  C  CD2   . LEU E 2 159 ? 216.085 204.646 233.896 1.00 18.56  ? 228 LEU F CD2   1 
ATOM   8455  N  N     . GLU E 2 160 ? 212.880 209.099 233.484 1.00 13.18  ? 229 GLU F N     1 
ATOM   8456  C  CA    . GLU E 2 160 ? 211.527 209.539 233.182 1.00 13.82  ? 229 GLU F CA    1 
ATOM   8457  C  C     . GLU E 2 160 ? 211.539 210.844 232.382 1.00 12.26  ? 229 GLU F C     1 
ATOM   8458  O  O     . GLU E 2 160 ? 210.783 210.993 231.421 1.00 11.54  ? 229 GLU F O     1 
ATOM   8459  C  CB    . GLU E 2 160 ? 210.697 209.672 234.456 1.00 15.64  ? 229 GLU F CB    1 
ATOM   8460  C  CG    . GLU E 2 160 ? 209.268 210.115 234.155 1.00 18.39  ? 229 GLU F CG    1 
ATOM   8461  C  CD    . GLU E 2 160 ? 208.259 209.662 235.192 1.00 21.66  ? 229 GLU F CD    1 
ATOM   8462  O  OE1   . GLU E 2 160 ? 208.631 208.852 236.076 1.00 25.75  ? 229 GLU F OE1   1 
ATOM   8463  O  OE2   . GLU E 2 160 ? 207.096 210.109 235.122 1.00 24.28  ? 229 GLU F OE2   1 
ATOM   8464  N  N     . SER E 2 161 ? 212.387 211.799 232.787 1.00 11.95  ? 230 SER F N     1 
ATOM   8465  C  CA    . SER E 2 161 ? 212.457 213.095 232.132 1.00 11.77  ? 230 SER F CA    1 
ATOM   8466  C  C     . SER E 2 161 ? 212.823 212.951 230.655 1.00 11.62  ? 230 SER F C     1 
ATOM   8467  O  O     . SER E 2 161 ? 212.214 213.572 229.789 1.00 11.55  ? 230 SER F O     1 
ATOM   8468  C  CB    . SER E 2 161 ? 213.413 214.021 232.835 1.00 11.89  ? 230 SER F CB    1 
ATOM   8469  O  OG    . SER E 2 161 ? 213.096 214.110 234.215 1.00 12.42  ? 230 SER F OG    1 
ATOM   8470  N  N     . GLU E 2 162 ? 213.834 212.134 230.365 1.00 12.23  ? 231 GLU F N     1 
ATOM   8471  C  CA    . GLU E 2 162 ? 214.259 211.910 228.990 1.00 13.31  ? 231 GLU F CA    1 
ATOM   8472  C  C     . GLU E 2 162 ? 213.135 211.246 228.194 1.00 12.29  ? 231 GLU F C     1 
ATOM   8473  O  O     . GLU E 2 162 ? 212.941 211.570 227.022 1.00 12.48  ? 231 GLU F O     1 
ATOM   8474  C  CB    . GLU E 2 162 ? 215.552 211.102 228.971 1.00 14.91  ? 231 GLU F CB    1 
ATOM   8475  C  CG    . GLU E 2 162 ? 216.263 211.075 227.619 1.00 18.22  ? 231 GLU F CG    1 
ATOM   8476  C  CD    . GLU E 2 162 ? 215.631 210.137 226.588 1.00 20.54  ? 231 GLU F CD    1 
ATOM   8477  O  OE1   . GLU E 2 162 ? 215.101 209.071 226.969 1.00 21.14  ? 231 GLU F OE1   1 
ATOM   8478  O  OE2   . GLU E 2 162 ? 215.689 210.470 225.390 1.00 22.14  ? 231 GLU F OE2   1 
ATOM   8479  N  N     . GLY E 2 163 ? 212.391 210.338 228.827 1.00 11.88  ? 232 GLY F N     1 
ATOM   8480  C  CA    . GLY E 2 163 ? 211.289 209.662 228.156 1.00 11.93  ? 232 GLY F CA    1 
ATOM   8481  C  C     . GLY E 2 163 ? 210.198 210.636 227.720 1.00 11.43  ? 232 GLY F C     1 
ATOM   8482  O  O     . GLY E 2 163 ? 209.693 210.555 226.607 1.00 12.10  ? 232 GLY F O     1 
ATOM   8483  N  N     . TRP E 2 164 ? 209.840 211.569 228.598 1.00 11.25  ? 233 TRP F N     1 
ATOM   8484  C  CA    . TRP E 2 164 ? 208.821 212.550 228.258 1.00 11.65  ? 233 TRP F CA    1 
ATOM   8485  C  C     . TRP E 2 164 ? 209.293 213.469 227.135 1.00 10.21  ? 233 TRP F C     1 
ATOM   8486  O  O     . TRP E 2 164 ? 208.509 213.823 226.257 1.00 9.99   ? 233 TRP F O     1 
ATOM   8487  C  CB    . TRP E 2 164 ? 208.411 213.366 229.482 1.00 12.59  ? 233 TRP F CB    1 
ATOM   8488  C  CG    . TRP E 2 164 ? 207.588 212.557 230.439 1.00 14.29  ? 233 TRP F CG    1 
ATOM   8489  C  CD1   . TRP E 2 164 ? 207.903 212.210 231.717 1.00 15.58  ? 233 TRP F CD1   1 
ATOM   8490  C  CD2   . TRP E 2 164 ? 206.299 211.979 230.166 1.00 15.62  ? 233 TRP F CD2   1 
ATOM   8491  N  NE1   . TRP E 2 164 ? 206.894 211.472 232.265 1.00 15.99  ? 233 TRP F NE1   1 
ATOM   8492  C  CE2   . TRP E 2 164 ? 205.902 211.305 231.340 1.00 16.76  ? 233 TRP F CE2   1 
ATOM   8493  C  CE3   . TRP E 2 164 ? 205.443 211.984 229.065 1.00 16.25  ? 233 TRP F CE3   1 
ATOM   8494  C  CZ2   . TRP E 2 164 ? 204.690 210.630 231.435 1.00 17.49  ? 233 TRP F CZ2   1 
ATOM   8495  C  CZ3   . TRP E 2 164 ? 204.238 211.321 229.160 1.00 17.74  ? 233 TRP F CZ3   1 
ATOM   8496  C  CH2   . TRP E 2 164 ? 203.876 210.647 230.328 1.00 17.98  ? 233 TRP F CH2   1 
ATOM   8497  N  N     . ASN E 2 165 ? 210.576 213.838 227.156 1.00 9.27   ? 234 ASN F N     1 
ATOM   8498  C  CA    . ASN E 2 165 ? 211.137 214.641 226.087 1.00 9.23   ? 234 ASN F CA    1 
ATOM   8499  C  C     . ASN E 2 165 ? 211.112 213.874 224.766 1.00 9.40   ? 234 ASN F C     1 
ATOM   8500  O  O     . ASN E 2 165 ? 210.770 214.431 223.725 1.00 9.27   ? 234 ASN F O     1 
ATOM   8501  C  CB    . ASN E 2 165 ? 212.549 215.109 226.419 1.00 8.82   ? 234 ASN F CB    1 
ATOM   8502  C  CG    . ASN E 2 165 ? 213.059 216.110 225.412 1.00 8.56   ? 234 ASN F CG    1 
ATOM   8503  O  OD1   . ASN E 2 165 ? 212.518 217.214 225.284 1.00 8.70   ? 234 ASN F OD1   1 
ATOM   8504  N  ND2   . ASN E 2 165 ? 214.111 215.750 224.698 1.00 8.74   ? 234 ASN F ND2   1 
ATOM   8505  N  N     . ARG E 2 166 ? 211.483 212.592 224.810 1.00 10.84  ? 235 ARG F N     1 
ATOM   8506  C  CA    . ARG E 2 166 ? 211.597 211.790 223.598 1.00 12.69  ? 235 ARG F CA    1 
ATOM   8507  C  C     . ARG E 2 166 ? 210.249 211.680 222.888 1.00 12.58  ? 235 ARG F C     1 
ATOM   8508  O  O     . ARG E 2 166 ? 210.171 211.810 221.672 1.00 13.01  ? 235 ARG F O     1 
ATOM   8509  C  CB    . ARG E 2 166 ? 212.122 210.397 223.942 1.00 14.56  ? 235 ARG F CB    1 
ATOM   8510  C  CG    . ARG E 2 166 ? 212.795 209.679 222.785 1.00 16.83  ? 235 ARG F CG    1 
ATOM   8511  C  CD    . ARG E 2 166 ? 213.019 208.213 223.094 1.00 17.81  ? 235 ARG F CD    1 
ATOM   8512  N  NE    . ARG E 2 166 ? 213.891 208.015 224.255 1.00 18.77  ? 235 ARG F NE    1 
ATOM   8513  C  CZ    . ARG E 2 166 ? 214.206 206.831 224.762 1.00 19.78  ? 235 ARG F CZ    1 
ATOM   8514  N  NH1   . ARG E 2 166 ? 213.796 205.722 224.166 1.00 20.78  ? 235 ARG F NH1   1 
ATOM   8515  N  NH2   . ARG E 2 166 ? 214.963 206.750 225.840 1.00 19.52  ? 235 ARG F NH2   1 
ATOM   8516  N  N     . ARG E 2 167 ? 209.173 211.496 223.653 1.00 13.59  ? 236 ARG F N     1 
ATOM   8517  C  CA    . ARG E 2 167 ? 207.850 211.308 223.079 1.00 15.39  ? 236 ARG F CA    1 
ATOM   8518  C  C     . ARG E 2 167 ? 207.174 212.621 222.690 1.00 14.33  ? 236 ARG F C     1 
ATOM   8519  O  O     . ARG E 2 167 ? 206.119 212.596 222.072 1.00 15.64  ? 236 ARG F O     1 
ATOM   8520  C  CB    . ARG E 2 167 ? 206.942 210.584 224.078 1.00 16.95  ? 236 ARG F CB    1 
ATOM   8521  C  CG    . ARG E 2 167 ? 207.420 209.178 224.396 1.00 20.32  ? 236 ARG F CG    1 
ATOM   8522  C  CD    . ARG E 2 167 ? 206.395 208.432 225.239 1.00 23.41  ? 236 ARG F CD    1 
ATOM   8523  N  NE    . ARG E 2 167 ? 206.333 208.939 226.611 1.00 23.89  ? 236 ARG F NE    1 
ATOM   8524  C  CZ    . ARG E 2 167 ? 207.188 208.595 227.571 1.00 25.10  ? 236 ARG F CZ    1 
ATOM   8525  N  NH1   . ARG E 2 167 ? 208.172 207.754 227.322 1.00 25.90  ? 236 ARG F NH1   1 
ATOM   8526  N  NH2   . ARG E 2 167 ? 207.065 209.101 228.781 1.00 24.68  ? 236 ARG F NH2   1 
ATOM   8527  N  N     . ASN E 2 168 ? 207.757 213.767 223.038 1.00 13.93  ? 237 ASN F N     1 
ATOM   8528  C  CA    . ASN E 2 168 ? 207.088 215.038 222.827 1.00 13.61  ? 237 ASN F CA    1 
ATOM   8529  C  C     . ASN E 2 168 ? 207.025 215.384 221.340 1.00 14.14  ? 237 ASN F C     1 
ATOM   8530  O  O     . ASN E 2 168 ? 207.862 214.959 220.553 1.00 14.95  ? 237 ASN F O     1 
ATOM   8531  C  CB    . ASN E 2 168 ? 207.773 216.154 223.606 1.00 12.91  ? 237 ASN F CB    1 
ATOM   8532  C  CG    . ASN E 2 168 ? 206.875 217.344 223.801 1.00 12.42  ? 237 ASN F CG    1 
ATOM   8533  O  OD1   . ASN E 2 168 ? 207.006 218.330 223.073 1.00 13.59  ? 237 ASN F OD1   1 
ATOM   8534  N  ND2   . ASN E 2 168 ? 205.984 217.280 224.775 1.00 11.89  ? 237 ASN F ND2   1 
ATOM   8535  N  N     . VAL E 2 169 ? 206.037 216.204 220.975 1.00 16.00  ? 238 VAL F N     1 
ATOM   8536  C  CA    . VAL E 2 169 ? 205.882 216.670 219.602 1.00 18.07  ? 238 VAL F CA    1 
ATOM   8537  C  C     . VAL E 2 169 ? 207.052 217.574 219.201 1.00 18.36  ? 238 VAL F C     1 
ATOM   8538  O  O     . VAL E 2 169 ? 207.416 217.612 218.028 1.00 19.43  ? 238 VAL F O     1 
ATOM   8539  C  CB    . VAL E 2 169 ? 204.530 217.392 219.439 1.00 19.54  ? 238 VAL F CB    1 
ATOM   8540  C  CG1   . VAL E 2 169 ? 204.447 218.672 220.268 1.00 20.59  ? 238 VAL F CG1   1 
ATOM   8541  C  CG2   . VAL E 2 169 ? 204.232 217.720 217.981 1.00 20.75  ? 238 VAL F CG2   1 
ATOM   8542  N  N     . ASP E 2 170 ? 207.641 218.301 220.162 1.00 18.38  ? 239 ASP F N     1 
ATOM   8543  C  CA    . ASP E 2 170 ? 208.778 219.170 219.898 1.00 19.99  ? 239 ASP F CA    1 
ATOM   8544  C  C     . ASP E 2 170 ? 209.835 218.959 220.977 1.00 16.56  ? 239 ASP F C     1 
ATOM   8545  O  O     . ASP E 2 170 ? 209.936 219.741 221.928 1.00 16.13  ? 239 ASP F O     1 
ATOM   8546  C  CB    . ASP E 2 170 ? 208.353 220.626 219.828 1.00 24.13  ? 239 ASP F CB    1 
ATOM   8547  C  CG    . ASP E 2 170 ? 209.334 221.525 219.096 1.00 29.03  ? 239 ASP F CG    1 
ATOM   8548  O  OD1   . ASP E 2 170 ? 210.128 220.985 218.298 1.00 32.13  ? 239 ASP F OD1   1 
ATOM   8549  O  OD2   . ASP E 2 170 ? 209.304 222.759 219.338 1.00 35.63  ? 239 ASP F OD2   1 
ATOM   8550  N  N     . PRO E 2 171 ? 210.631 217.876 220.894 1.00 13.78  ? 240 PRO F N     1 
ATOM   8551  C  CA    . PRO E 2 171 ? 211.587 217.564 221.951 1.00 12.40  ? 240 PRO F CA    1 
ATOM   8552  C  C     . PRO E 2 171 ? 212.642 218.650 222.122 1.00 11.10  ? 240 PRO F C     1 
ATOM   8553  O  O     . PRO E 2 171 ? 213.027 219.304 221.162 1.00 10.59  ? 240 PRO F O     1 
ATOM   8554  C  CB    . PRO E 2 171 ? 212.212 216.238 221.516 1.00 12.69  ? 240 PRO F CB    1 
ATOM   8555  C  CG    . PRO E 2 171 ? 211.264 215.699 220.485 1.00 13.58  ? 240 PRO F CG    1 
ATOM   8556  C  CD    . PRO E 2 171 ? 210.667 216.905 219.795 1.00 13.67  ? 240 PRO F CD    1 
ATOM   8557  N  N     . PHE E 2 172 ? 213.110 218.819 223.364 1.00 10.65  ? 241 PHE F N     1 
ATOM   8558  C  CA    . PHE E 2 172 ? 214.317 219.588 223.622 1.00 10.33  ? 241 PHE F CA    1 
ATOM   8559  C  C     . PHE E 2 172 ? 215.545 218.855 223.089 1.00 10.00  ? 241 PHE F C     1 
ATOM   8560  O  O     . PHE E 2 172 ? 215.541 217.641 222.927 1.00 10.24  ? 241 PHE F O     1 
ATOM   8561  C  CB    . PHE E 2 172 ? 214.534 219.807 225.121 1.00 10.26  ? 241 PHE F CB    1 
ATOM   8562  C  CG    . PHE E 2 172 ? 213.669 220.901 225.716 1.00 10.24  ? 241 PHE F CG    1 
ATOM   8563  C  CD1   . PHE E 2 172 ? 214.019 222.236 225.551 1.00 10.62  ? 241 PHE F CD1   1 
ATOM   8564  C  CD2   . PHE E 2 172 ? 212.536 220.587 226.454 1.00 10.30  ? 241 PHE F CD2   1 
ATOM   8565  C  CE1   . PHE E 2 172 ? 213.239 223.236 226.118 1.00 10.55  ? 241 PHE F CE1   1 
ATOM   8566  C  CE2   . PHE E 2 172 ? 211.761 221.590 227.015 1.00 10.55  ? 241 PHE F CE2   1 
ATOM   8567  C  CZ    . PHE E 2 172 ? 212.113 222.911 226.833 1.00 10.61  ? 241 PHE F CZ    1 
ATOM   8568  N  N     . HIS E 2 173 ? 216.628 219.599 222.851 1.00 10.73  ? 242 HIS F N     1 
ATOM   8569  C  CA    . HIS E 2 173 ? 217.946 219.011 222.676 1.00 11.07  ? 242 HIS F CA    1 
ATOM   8570  C  C     . HIS E 2 173 ? 218.559 218.914 224.074 1.00 10.79  ? 242 HIS F C     1 
ATOM   8571  O  O     . HIS E 2 173 ? 219.190 219.864 224.527 1.00 10.99  ? 242 HIS F O     1 
ATOM   8572  C  CB    . HIS E 2 173 ? 218.767 219.895 221.729 1.00 12.00  ? 242 HIS F CB    1 
ATOM   8573  C  CG    . HIS E 2 173 ? 220.127 219.372 221.413 1.00 14.13  ? 242 HIS F CG    1 
ATOM   8574  N  ND1   . HIS E 2 173 ? 221.111 220.151 220.856 1.00 16.44  ? 242 HIS F ND1   1 
ATOM   8575  C  CD2   . HIS E 2 173 ? 220.671 218.176 221.561 1.00 16.59  ? 242 HIS F CD2   1 
ATOM   8576  C  CE1   . HIS E 2 173 ? 222.206 219.419 220.694 1.00 16.49  ? 242 HIS F CE1   1 
ATOM   8577  N  NE2   . HIS E 2 173 ? 221.959 218.219 221.111 1.00 15.99  ? 242 HIS F NE2   1 
ATOM   8578  N  N     . ILE E 2 174 ? 218.374 217.773 224.731 1.00 10.52  ? 243 ILE F N     1 
ATOM   8579  C  CA    . ILE E 2 174 ? 218.799 217.606 226.107 1.00 11.00  ? 243 ILE F CA    1 
ATOM   8580  C  C     . ILE E 2 174 ? 220.315 217.541 226.187 1.00 11.73  ? 243 ILE F C     1 
ATOM   8581  O  O     . ILE E 2 174 ? 220.950 216.785 225.472 1.00 10.97  ? 243 ILE F O     1 
ATOM   8582  C  CB    . ILE E 2 174 ? 218.129 216.378 226.741 1.00 11.43  ? 243 ILE F CB    1 
ATOM   8583  C  CG1   . ILE E 2 174 ? 216.679 216.693 227.105 1.00 11.69  ? 243 ILE F CG1   1 
ATOM   8584  C  CG2   . ILE E 2 174 ? 218.902 215.892 227.964 1.00 11.73  ? 243 ILE F CG2   1 
ATOM   8585  C  CD1   . ILE E 2 174 ? 215.913 215.491 227.604 1.00 12.35  ? 243 ILE F CD1   1 
ATOM   8586  N  N     . TYR E 2 175 ? 220.884 218.310 227.123 1.00 12.41  ? 244 TYR F N     1 
ATOM   8587  C  CA    . TYR E 2 175 ? 222.305 218.255 227.417 1.00 13.76  ? 244 TYR F CA    1 
ATOM   8588  C  C     . TYR E 2 175 ? 222.493 217.732 228.838 1.00 14.07  ? 244 TYR F C     1 
ATOM   8589  O  O     . TYR E 2 175 ? 221.872 218.239 229.766 1.00 16.14  ? 244 TYR F O     1 
ATOM   8590  C  CB    . TYR E 2 175 ? 222.945 219.646 227.318 1.00 14.31  ? 244 TYR F CB    1 
ATOM   8591  C  CG    . TYR E 2 175 ? 223.270 220.079 225.900 1.00 14.57  ? 244 TYR F CG    1 
ATOM   8592  C  CD1   . TYR E 2 175 ? 222.276 220.534 225.038 1.00 14.77  ? 244 TYR F CD1   1 
ATOM   8593  C  CD2   . TYR E 2 175 ? 224.576 220.031 225.434 1.00 15.95  ? 244 TYR F CD2   1 
ATOM   8594  C  CE1   . TYR E 2 175 ? 222.583 220.941 223.755 1.00 15.73  ? 244 TYR F CE1   1 
ATOM   8595  C  CE2   . TYR E 2 175 ? 224.891 220.418 224.142 1.00 16.65  ? 244 TYR F CE2   1 
ATOM   8596  C  CZ    . TYR E 2 175 ? 223.895 220.879 223.307 1.00 16.34  ? 244 TYR F CZ    1 
ATOM   8597  O  OH    . TYR E 2 175 ? 224.190 221.281 222.038 1.00 18.85  ? 244 TYR F OH    1 
ATOM   8598  N  N     . PHE E 2 176 ? 223.358 216.731 228.992 1.00 14.68  ? 245 PHE F N     1 
ATOM   8599  C  CA    . PHE E 2 176 ? 223.838 216.293 230.289 1.00 15.59  ? 245 PHE F CA    1 
ATOM   8600  C  C     . PHE E 2 176 ? 225.216 216.907 230.507 1.00 16.99  ? 245 PHE F C     1 
ATOM   8601  O  O     . PHE E 2 176 ? 226.205 216.398 229.995 1.00 17.87  ? 245 PHE F O     1 
ATOM   8602  C  CB    . PHE E 2 176 ? 223.880 214.767 230.365 1.00 16.23  ? 245 PHE F CB    1 
ATOM   8603  C  CG    . PHE E 2 176 ? 222.525 214.106 230.568 1.00 16.85  ? 245 PHE F CG    1 
ATOM   8604  C  CD1   . PHE E 2 176 ? 221.352 214.860 230.614 1.00 17.10  ? 245 PHE F CD1   1 
ATOM   8605  C  CD2   . PHE E 2 176 ? 222.430 212.730 230.694 1.00 17.57  ? 245 PHE F CD2   1 
ATOM   8606  C  CE1   . PHE E 2 176 ? 220.119 214.254 230.809 1.00 17.35  ? 245 PHE F CE1   1 
ATOM   8607  C  CE2   . PHE E 2 176 ? 221.196 212.122 230.875 1.00 17.84  ? 245 PHE F CE2   1 
ATOM   8608  C  CZ    . PHE E 2 176 ? 220.043 212.886 230.938 1.00 17.21  ? 245 PHE F CZ    1 
ATOM   8609  N  N     . CYS E 2 177 ? 225.257 217.999 231.276 1.00 17.47  ? 246 CYS F N     1 
ATOM   8610  C  CA    . CYS E 2 177 ? 226.481 218.744 231.520 1.00 17.96  ? 246 CYS F CA    1 
ATOM   8611  C  C     . CYS E 2 177 ? 227.076 218.401 232.884 1.00 18.95  ? 246 CYS F C     1 
ATOM   8612  O  O     . CYS E 2 177 ? 226.377 217.980 233.801 1.00 18.67  ? 246 CYS F O     1 
ATOM   8613  C  CB    . CYS E 2 177 ? 226.229 220.239 231.425 1.00 18.81  ? 246 CYS F CB    1 
ATOM   8614  S  SG    . CYS E 2 177 ? 225.915 220.814 229.731 1.00 21.28  ? 246 CYS F SG    1 
ATOM   8615  N  N     . ASN E 2 178 ? 228.399 218.601 233.000 1.00 20.83  ? 247 ASN F N     1 
ATOM   8616  C  CA    . ASN E 2 178 ? 229.154 218.305 234.213 1.00 21.57  ? 247 ASN F CA    1 
ATOM   8617  C  C     . ASN E 2 178 ? 228.992 216.842 234.614 1.00 21.17  ? 247 ASN F C     1 
ATOM   8618  O  O     . ASN E 2 178 ? 228.938 216.519 235.802 1.00 23.89  ? 247 ASN F O     1 
ATOM   8619  C  CB    . ASN E 2 178 ? 228.763 219.215 235.377 1.00 23.43  ? 247 ASN F CB    1 
ATOM   8620  C  CG    . ASN E 2 178 ? 229.224 220.637 235.169 1.00 25.05  ? 247 ASN F CG    1 
ATOM   8621  O  OD1   . ASN E 2 178 ? 230.430 220.877 235.042 1.00 28.47  ? 247 ASN F OD1   1 
ATOM   8622  N  ND2   . ASN E 2 178 ? 228.299 221.584 235.144 1.00 23.89  ? 247 ASN F ND2   1 
ATOM   8623  N  N     . LEU E 2 179 ? 228.923 215.958 233.615 1.00 22.19  ? 248 LEU F N     1 
ATOM   8624  C  CA    . LEU E 2 179 ? 228.778 214.534 233.855 1.00 24.23  ? 248 LEU F CA    1 
ATOM   8625  C  C     . LEU E 2 179 ? 230.153 213.884 233.777 1.00 27.60  ? 248 LEU F C     1 
ATOM   8626  O  O     . LEU E 2 179 ? 230.677 213.659 232.688 1.00 29.21  ? 248 LEU F O     1 
ATOM   8627  C  CB    . LEU E 2 179 ? 227.805 213.922 232.847 1.00 23.14  ? 248 LEU F CB    1 
ATOM   8628  C  CG    . LEU E 2 179 ? 227.471 212.442 233.054 1.00 23.09  ? 248 LEU F CG    1 
ATOM   8629  C  CD1   . LEU E 2 179 ? 226.895 212.211 234.430 1.00 23.38  ? 248 LEU F CD1   1 
ATOM   8630  C  CD2   . LEU E 2 179 ? 226.533 211.940 231.977 1.00 23.71  ? 248 LEU F CD2   1 
ATOM   8631  N  N     . LYS E 2 180 ? 230.721 213.566 234.939 1.00 34.02  ? 249 LYS F N     1 
ATOM   8632  C  CA    . LYS E 2 180 ? 232.006 212.886 235.000 1.00 38.16  ? 249 LYS F CA    1 
ATOM   8633  C  C     . LYS E 2 180 ? 231.868 211.474 234.438 1.00 38.54  ? 249 LYS F C     1 
ATOM   8634  O  O     . LYS E 2 180 ? 230.913 210.768 234.753 1.00 38.79  ? 249 LYS F O     1 
ATOM   8635  C  CB    . LYS E 2 180 ? 232.513 212.825 236.443 1.00 44.81  ? 249 LYS F CB    1 
ATOM   8636  C  CG    . LYS E 2 180 ? 232.701 214.164 237.144 1.00 54.09  ? 249 LYS F CG    1 
ATOM   8637  C  CD    . LYS E 2 180 ? 233.843 215.029 236.616 1.00 62.80  ? 249 LYS F CD    1 
ATOM   8638  C  CE    . LYS E 2 180 ? 233.437 216.025 235.566 1.00 68.91  ? 249 LYS F CE    1 
ATOM   8639  N  NZ    . LYS E 2 180 ? 234.563 216.877 235.166 1.00 72.65  ? 249 LYS F NZ    1 
ATOM   8640  N  N     . ILE E 2 181 ? 232.836 211.059 233.616 1.00 42.23  ? 250 ILE F N     1 
ATOM   8641  C  CA    . ILE E 2 181 ? 232.780 209.759 232.964 1.00 46.68  ? 250 ILE F CA    1 
ATOM   8642  C  C     . ILE E 2 181 ? 232.807 208.629 233.992 1.00 48.38  ? 250 ILE F C     1 
ATOM   8643  O  O     . ILE E 2 181 ? 232.021 207.688 233.895 1.00 50.78  ? 250 ILE F O     1 
ATOM   8644  C  CB    . ILE E 2 181 ? 233.915 209.616 231.936 1.00 50.27  ? 250 ILE F CB    1 
ATOM   8645  C  CG1   . ILE E 2 181 ? 233.796 210.669 230.840 1.00 54.14  ? 250 ILE F CG1   1 
ATOM   8646  C  CG2   . ILE E 2 181 ? 233.957 208.204 231.353 1.00 51.97  ? 250 ILE F CG2   1 
ATOM   8647  C  CD1   . ILE E 2 181 ? 232.509 210.599 230.041 1.00 55.92  ? 250 ILE F CD1   1 
ATOM   8648  N  N     . ASP E 2 182 ? 233.697 208.717 234.979 1.00 51.04  ? 251 ASP F N     1 
ATOM   8649  C  CA    . ASP E 2 182 ? 233.855 207.636 235.944 1.00 56.78  ? 251 ASP F CA    1 
ATOM   8650  C  C     . ASP E 2 182 ? 232.962 207.834 237.171 1.00 50.10  ? 251 ASP F C     1 
ATOM   8651  O  O     . ASP E 2 182 ? 233.027 207.043 238.111 1.00 51.96  ? 251 ASP F O     1 
ATOM   8652  C  CB    . ASP E 2 182 ? 235.305 207.532 236.391 1.00 64.88  ? 251 ASP F CB    1 
ATOM   8653  C  CG    . ASP E 2 182 ? 235.780 208.705 237.236 1.00 72.14  ? 251 ASP F CG    1 
ATOM   8654  O  OD1   . ASP E 2 182 ? 235.405 209.847 236.894 1.00 72.71  ? 251 ASP F OD1   1 
ATOM   8655  O  OD2   . ASP E 2 182 ? 236.511 208.467 238.224 1.00 77.72  ? 251 ASP F OD2   1 
ATOM   8656  N  N     . GLY E 2 183 ? 232.143 208.896 237.185 1.00 42.23  ? 252 GLY F N     1 
ATOM   8657  C  CA    . GLY E 2 183 ? 231.361 209.236 238.362 1.00 37.32  ? 252 GLY F CA    1 
ATOM   8658  C  C     . GLY E 2 183 ? 230.242 208.231 238.622 1.00 34.11  ? 252 GLY F C     1 
ATOM   8659  O  O     . GLY E 2 183 ? 229.869 207.436 237.758 1.00 33.18  ? 252 GLY F O     1 
ATOM   8660  N  N     . ALA E 2 184 ? 229.687 208.304 239.831 1.00 31.56  ? 253 ALA F N     1 
ATOM   8661  C  CA    . ALA E 2 184 ? 228.616 207.411 240.235 1.00 31.60  ? 253 ALA F CA    1 
ATOM   8662  C  C     . ALA E 2 184 ? 227.372 207.654 239.380 1.00 29.81  ? 253 ALA F C     1 
ATOM   8663  O  O     . ALA E 2 184 ? 226.682 206.709 239.003 1.00 29.67  ? 253 ALA F O     1 
ATOM   8664  C  CB    . ALA E 2 184 ? 228.309 207.581 241.709 1.00 31.55  ? 253 ALA F CB    1 
ATOM   8665  N  N     . LEU E 2 185 ? 227.076 208.923 239.091 1.00 27.92  ? 254 LEU F N     1 
ATOM   8666  C  CA    . LEU E 2 185 ? 225.892 209.256 238.314 1.00 28.08  ? 254 LEU F CA    1 
ATOM   8667  C  C     . LEU E 2 185 ? 225.995 208.657 236.912 1.00 25.59  ? 254 LEU F C     1 
ATOM   8668  O  O     . LEU E 2 185 ? 225.026 208.122 236.387 1.00 24.57  ? 254 LEU F O     1 
ATOM   8669  C  CB    . LEU E 2 185 ? 225.731 210.771 238.257 1.00 30.32  ? 254 LEU F CB    1 
ATOM   8670  C  CG    . LEU E 2 185 ? 224.345 211.309 237.908 1.00 32.97  ? 254 LEU F CG    1 
ATOM   8671  C  CD1   . LEU E 2 185 ? 223.297 210.822 238.887 1.00 32.52  ? 254 LEU F CD1   1 
ATOM   8672  C  CD2   . LEU E 2 185 ? 224.404 212.831 237.930 1.00 33.89  ? 254 LEU F CD2   1 
ATOM   8673  N  N     . HIS E 2 186 ? 227.173 208.753 236.297 1.00 23.97  ? 255 HIS F N     1 
ATOM   8674  C  CA    . HIS E 2 186 ? 227.385 208.189 234.974 1.00 24.37  ? 255 HIS F CA    1 
ATOM   8675  C  C     . HIS E 2 186 ? 227.280 206.666 235.002 1.00 24.96  ? 255 HIS F C     1 
ATOM   8676  O  O     . HIS E 2 186 ? 226.692 206.069 234.101 1.00 24.41  ? 255 HIS F O     1 
ATOM   8677  C  CB    . HIS E 2 186 ? 228.736 208.636 234.412 1.00 25.86  ? 255 HIS F CB    1 
ATOM   8678  C  CG    . HIS E 2 186 ? 228.993 208.167 233.021 1.00 28.05  ? 255 HIS F CG    1 
ATOM   8679  N  ND1   . HIS E 2 186 ? 229.667 206.999 232.745 1.00 30.05  ? 255 HIS F ND1   1 
ATOM   8680  C  CD2   . HIS E 2 186 ? 228.678 208.707 231.827 1.00 29.68  ? 255 HIS F CD2   1 
ATOM   8681  C  CE1   . HIS E 2 186 ? 229.741 206.839 231.430 1.00 31.14  ? 255 HIS F CE1   1 
ATOM   8682  N  NE2   . HIS E 2 186 ? 229.148 207.862 230.852 1.00 30.22  ? 255 HIS F NE2   1 
ATOM   8683  N  N     . ARG E 2 187 ? 227.849 206.040 236.035 1.00 24.90  ? 256 ARG F N     1 
ATOM   8684  C  CA    . ARG E 2 187 ? 227.817 204.591 236.152 1.00 27.15  ? 256 ARG F CA    1 
ATOM   8685  C  C     . ARG E 2 187 ? 226.386 204.074 236.294 1.00 24.90  ? 256 ARG F C     1 
ATOM   8686  O  O     . ARG E 2 187 ? 226.010 203.080 235.669 1.00 23.77  ? 256 ARG F O     1 
ATOM   8687  C  CB    . ARG E 2 187 ? 228.679 204.109 237.321 1.00 31.46  ? 256 ARG F CB    1 
ATOM   8688  C  CG    . ARG E 2 187 ? 230.171 204.171 237.025 1.00 39.37  ? 256 ARG F CG    1 
ATOM   8689  C  CD    . ARG E 2 187 ? 230.953 203.116 237.792 1.00 46.88  ? 256 ARG F CD    1 
ATOM   8690  N  NE    . ARG E 2 187 ? 230.483 202.988 239.176 1.00 52.31  ? 256 ARG F NE    1 
ATOM   8691  C  CZ    . ARG E 2 187 ? 230.626 203.905 240.126 1.00 59.52  ? 256 ARG F CZ    1 
ATOM   8692  N  NH1   . ARG E 2 187 ? 231.317 205.010 239.895 1.00 61.93  ? 256 ARG F NH1   1 
ATOM   8693  N  NH2   . ARG E 2 187 ? 230.088 203.699 241.319 1.00 61.66  ? 256 ARG F NH2   1 
ATOM   8694  N  N     . GLU E 2 188 ? 225.584 204.751 237.118 1.00 23.64  ? 257 GLU F N     1 
ATOM   8695  C  CA    . GLU E 2 188 ? 224.197 204.357 237.297 1.00 25.79  ? 257 GLU F CA    1 
ATOM   8696  C  C     . GLU E 2 188 ? 223.400 204.555 236.006 1.00 22.02  ? 257 GLU F C     1 
ATOM   8697  O  O     . GLU E 2 188 ? 222.542 203.736 235.671 1.00 23.74  ? 257 GLU F O     1 
ATOM   8698  C  CB    . GLU E 2 188 ? 223.572 205.121 238.464 1.00 28.94  ? 257 GLU F CB    1 
ATOM   8699  C  CG    . GLU E 2 188 ? 222.130 204.711 238.731 1.00 33.34  ? 257 GLU F CG    1 
ATOM   8700  C  CD    . GLU E 2 188 ? 221.983 203.312 239.302 1.00 39.96  ? 257 GLU F CD    1 
ATOM   8701  O  OE1   . GLU E 2 188 ? 223.005 202.687 239.673 1.00 41.51  ? 257 GLU F OE1   1 
ATOM   8702  O  OE2   . GLU E 2 188 ? 220.823 202.843 239.365 1.00 47.04  ? 257 GLU F OE2   1 
ATOM   8703  N  N     . LEU E 2 189 ? 223.676 205.644 235.289 1.00 20.75  ? 258 LEU F N     1 
ATOM   8704  C  CA    . LEU E 2 189 ? 223.001 205.907 234.025 1.00 20.34  ? 258 LEU F CA    1 
ATOM   8705  C  C     . LEU E 2 189 ? 223.294 204.793 233.025 1.00 21.81  ? 258 LEU F C     1 
ATOM   8706  O  O     . LEU E 2 189 ? 222.398 204.355 232.296 1.00 21.88  ? 258 LEU F O     1 
ATOM   8707  C  CB    . LEU E 2 189 ? 223.397 207.267 233.462 1.00 19.32  ? 258 LEU F CB    1 
ATOM   8708  C  CG    . LEU E 2 189 ? 222.699 208.483 234.075 1.00 18.82  ? 258 LEU F CG    1 
ATOM   8709  C  CD1   . LEU E 2 189 ? 223.419 209.773 233.729 1.00 18.79  ? 258 LEU F CD1   1 
ATOM   8710  C  CD2   . LEU E 2 189 ? 221.259 208.562 233.606 1.00 18.55  ? 258 LEU F CD2   1 
ATOM   8711  N  N     . VAL E 2 190 ? 224.552 204.343 232.976 1.00 23.30  ? 259 VAL F N     1 
ATOM   8712  C  CA    . VAL E 2 190 ? 224.933 203.263 232.080 1.00 24.87  ? 259 VAL F CA    1 
ATOM   8713  C  C     . VAL E 2 190 ? 224.244 201.966 232.497 1.00 25.67  ? 259 VAL F C     1 
ATOM   8714  O  O     . VAL E 2 190 ? 223.802 201.201 231.635 1.00 27.21  ? 259 VAL F O     1 
ATOM   8715  C  CB    . VAL E 2 190 ? 226.463 203.121 232.030 1.00 26.36  ? 259 VAL F CB    1 
ATOM   8716  C  CG1   . VAL E 2 190 ? 226.901 201.858 231.304 1.00 27.45  ? 259 VAL F CG1   1 
ATOM   8717  C  CG2   . VAL E 2 190 ? 227.091 204.348 231.386 1.00 27.61  ? 259 VAL F CG2   1 
ATOM   8718  N  N     . LYS E 2 191 ? 224.137 201.731 233.806 1.00 27.05  ? 260 LYS F N     1 
ATOM   8719  C  CA    . LYS E 2 191 ? 223.501 200.520 234.301 1.00 30.33  ? 260 LYS F CA    1 
ATOM   8720  C  C     . LYS E 2 191 ? 222.025 200.473 233.910 1.00 28.65  ? 260 LYS F C     1 
ATOM   8721  O  O     . LYS E 2 191 ? 221.550 199.448 233.425 1.00 31.34  ? 260 LYS F O     1 
ATOM   8722  C  CB    . LYS E 2 191 ? 223.633 200.421 235.819 1.00 36.92  ? 260 LYS F CB    1 
ATOM   8723  C  CG    . LYS E 2 191 ? 224.885 199.747 236.293 1.00 45.50  ? 260 LYS F CG    1 
ATOM   8724  C  CD    . LYS E 2 191 ? 225.032 199.769 237.808 1.00 50.60  ? 260 LYS F CD    1 
ATOM   8725  C  CE    . LYS E 2 191 ? 223.805 199.344 238.571 1.00 53.85  ? 260 LYS F CE    1 
ATOM   8726  N  NZ    . LYS E 2 191 ? 223.443 197.942 238.335 1.00 55.75  ? 260 LYS F NZ    1 
ATOM   8727  N  N     . ARG E 2 192 ? 221.300 201.576 234.118 1.00 25.98  ? 261 ARG F N     1 
ATOM   8728  C  CA    . ARG E 2 192 ? 219.875 201.588 233.835 1.00 24.99  ? 261 ARG F CA    1 
ATOM   8729  C  C     . ARG E 2 192 ? 219.617 201.512 232.330 1.00 25.85  ? 261 ARG F C     1 
ATOM   8730  O  O     . ARG E 2 192 ? 218.650 200.882 231.904 1.00 29.68  ? 261 ARG F O     1 
ATOM   8731  C  CB    . ARG E 2 192 ? 219.208 202.822 234.444 1.00 24.44  ? 261 ARG F CB    1 
ATOM   8732  C  CG    . ARG E 2 192 ? 219.339 202.942 235.955 1.00 24.37  ? 261 ARG F CG    1 
ATOM   8733  C  CD    . ARG E 2 192 ? 218.658 201.834 236.702 1.00 24.84  ? 261 ARG F CD    1 
ATOM   8734  N  NE    . ARG E 2 192 ? 217.210 201.880 236.488 1.00 26.79  ? 261 ARG F NE    1 
ATOM   8735  C  CZ    . ARG E 2 192 ? 216.370 202.730 237.078 1.00 27.48  ? 261 ARG F CZ    1 
ATOM   8736  N  NH1   . ARG E 2 192 ? 216.814 203.610 237.965 1.00 27.07  ? 261 ARG F NH1   1 
ATOM   8737  N  NH2   . ARG E 2 192 ? 215.078 202.659 236.805 1.00 27.39  ? 261 ARG F NH2   1 
ATOM   8738  N  N     . TYR E 2 193 ? 220.462 202.157 231.519 1.00 24.36  ? 262 TYR F N     1 
ATOM   8739  C  CA    . TYR E 2 193 ? 220.219 202.228 230.086 1.00 23.52  ? 262 TYR F CA    1 
ATOM   8740  C  C     . TYR E 2 193 ? 220.830 201.050 229.328 1.00 26.06  ? 262 TYR F C     1 
ATOM   8741  O  O     . TYR E 2 193 ? 220.338 200.712 228.252 1.00 27.60  ? 262 TYR F O     1 
ATOM   8742  C  CB    . TYR E 2 193 ? 220.759 203.532 229.494 1.00 21.12  ? 262 TYR F CB    1 
ATOM   8743  C  CG    . TYR E 2 193 ? 219.809 204.705 229.661 1.00 20.23  ? 262 TYR F CG    1 
ATOM   8744  C  CD1   . TYR E 2 193 ? 218.551 204.694 229.069 1.00 19.79  ? 262 TYR F CD1   1 
ATOM   8745  C  CD2   . TYR E 2 193 ? 220.186 205.837 230.365 1.00 19.22  ? 262 TYR F CD2   1 
ATOM   8746  C  CE1   . TYR E 2 193 ? 217.684 205.767 229.189 1.00 20.03  ? 262 TYR F CE1   1 
ATOM   8747  C  CE2   . TYR E 2 193 ? 219.334 206.922 230.486 1.00 19.88  ? 262 TYR F CE2   1 
ATOM   8748  C  CZ    . TYR E 2 193 ? 218.083 206.891 229.892 1.00 20.09  ? 262 TYR F CZ    1 
ATOM   8749  O  OH    . TYR E 2 193 ? 217.247 207.953 230.030 1.00 21.27  ? 262 TYR F OH    1 
ATOM   8750  N  N     . GLN E 2 194 ? 221.912 200.459 229.855 1.00 31.24  ? 263 GLN F N     1 
ATOM   8751  C  CA    . GLN E 2 194 ? 222.606 199.356 229.201 1.00 35.95  ? 263 GLN F CA    1 
ATOM   8752  C  C     . GLN E 2 194 ? 223.147 199.842 227.856 1.00 35.34  ? 263 GLN F C     1 
ATOM   8753  O  O     . GLN E 2 194 ? 223.805 200.876 227.815 1.00 36.41  ? 263 GLN F O     1 
ATOM   8754  C  CB    . GLN E 2 194 ? 221.724 198.110 229.136 1.00 41.49  ? 263 GLN F CB    1 
ATOM   8755  C  CG    . GLN E 2 194 ? 221.385 197.525 230.503 1.00 47.09  ? 263 GLN F CG    1 
ATOM   8756  C  CD    . GLN E 2 194 ? 220.654 196.207 230.392 1.00 53.47  ? 263 GLN F CD    1 
ATOM   8757  O  OE1   . GLN E 2 194 ? 219.427 196.146 230.236 1.00 55.74  ? 263 GLN F OE1   1 
ATOM   8758  N  NE2   . GLN E 2 194 ? 221.421 195.130 230.478 1.00 58.02  ? 263 GLN F NE2   1 
ATOM   8759  N  N     . GLU E 2 195 ? 222.875 199.126 226.760 1.00 35.01  ? 264 GLU F N     1 
ATOM   8760  C  CA    . GLU E 2 195 ? 223.415 199.513 225.464 1.00 37.48  ? 264 GLU F CA    1 
ATOM   8761  C  C     . GLU E 2 195 ? 222.670 200.702 224.857 1.00 31.03  ? 264 GLU F C     1 
ATOM   8762  O  O     . GLU E 2 195 ? 223.142 201.285 223.883 1.00 31.12  ? 264 GLU F O     1 
ATOM   8763  C  CB    . GLU E 2 195 ? 223.390 198.361 224.463 1.00 44.67  ? 264 GLU F CB    1 
ATOM   8764  C  CG    . GLU E 2 195 ? 222.006 197.756 224.263 1.00 56.37  ? 264 GLU F CG    1 
ATOM   8765  C  CD    . GLU E 2 195 ? 221.712 196.568 225.170 1.00 65.67  ? 264 GLU F CD    1 
ATOM   8766  O  OE1   . GLU E 2 195 ? 222.489 196.355 226.134 1.00 66.10  ? 264 GLU F OE1   1 
ATOM   8767  O  OE2   . GLU E 2 195 ? 220.719 195.856 224.904 1.00 66.47  ? 264 GLU F OE2   1 
ATOM   8768  N  N     . LYS E 2 196 ? 221.500 201.054 225.404 1.00 27.47  ? 265 LYS F N     1 
ATOM   8769  C  CA    . LYS E 2 196 ? 220.760 202.208 224.920 1.00 24.56  ? 265 LYS F CA    1 
ATOM   8770  C  C     . LYS E 2 196 ? 221.532 203.506 225.172 1.00 22.48  ? 265 LYS F C     1 
ATOM   8771  O  O     . LYS E 2 196 ? 221.293 204.504 224.495 1.00 21.09  ? 265 LYS F O     1 
ATOM   8772  C  CB    . LYS E 2 196 ? 219.386 202.261 225.587 1.00 24.66  ? 265 LYS F CB    1 
ATOM   8773  C  CG    . LYS E 2 196 ? 218.484 203.374 225.099 1.00 26.08  ? 265 LYS F CG    1 
ATOM   8774  C  CD    . LYS E 2 196 ? 218.173 203.274 223.617 1.00 27.25  ? 265 LYS F CD    1 
ATOM   8775  C  CE    . LYS E 2 196 ? 217.135 204.262 223.218 1.00 29.95  ? 265 LYS F CE    1 
ATOM   8776  N  NZ    . LYS E 2 196 ? 217.270 204.589 221.799 1.00 32.38  ? 265 LYS F NZ    1 
ATOM   8777  N  N     . TRP E 2 197 ? 222.424 203.513 226.174 1.00 21.51  ? 266 TRP F N     1 
ATOM   8778  C  CA    . TRP E 2 197 ? 223.087 204.736 226.600 1.00 22.56  ? 266 TRP F CA    1 
ATOM   8779  C  C     . TRP E 2 197 ? 223.837 205.413 225.455 1.00 24.02  ? 266 TRP F C     1 
ATOM   8780  O  O     . TRP E 2 197 ? 223.758 206.627 225.291 1.00 24.55  ? 266 TRP F O     1 
ATOM   8781  C  CB    . TRP E 2 197 ? 224.036 204.453 227.765 1.00 22.08  ? 266 TRP F CB    1 
ATOM   8782  C  CG    . TRP E 2 197 ? 224.931 205.616 228.082 1.00 21.84  ? 266 TRP F CG    1 
ATOM   8783  C  CD1   . TRP E 2 197 ? 226.265 205.725 227.823 1.00 21.44  ? 266 TRP F CD1   1 
ATOM   8784  C  CD2   . TRP E 2 197 ? 224.534 206.856 228.700 1.00 21.09  ? 266 TRP F CD2   1 
ATOM   8785  N  NE1   . TRP E 2 197 ? 226.733 206.932 228.269 1.00 21.49  ? 266 TRP F NE1   1 
ATOM   8786  C  CE2   . TRP E 2 197 ? 225.696 207.647 228.805 1.00 21.11  ? 266 TRP F CE2   1 
ATOM   8787  C  CE3   . TRP E 2 197 ? 223.321 207.361 229.177 1.00 20.88  ? 266 TRP F CE3   1 
ATOM   8788  C  CZ2   . TRP E 2 197 ? 225.678 208.923 229.361 1.00 21.83  ? 266 TRP F CZ2   1 
ATOM   8789  C  CZ3   . TRP E 2 197 ? 223.301 208.628 229.718 1.00 21.79  ? 266 TRP F CZ3   1 
ATOM   8790  C  CH2   . TRP E 2 197 ? 224.465 209.396 229.811 1.00 22.30  ? 266 TRP F CH2   1 
ATOM   8791  N  N     . ASP E 2 198 ? 224.561 204.626 224.657 1.00 26.23  ? 267 ASP F N     1 
ATOM   8792  C  CA    . ASP E 2 198 ? 225.329 205.182 223.557 1.00 28.16  ? 267 ASP F CA    1 
ATOM   8793  C  C     . ASP E 2 198 ? 224.423 205.639 222.413 1.00 26.26  ? 267 ASP F C     1 
ATOM   8794  O  O     . ASP E 2 198 ? 224.881 206.360 221.536 1.00 26.32  ? 267 ASP F O     1 
ATOM   8795  C  CB    . ASP E 2 198 ? 226.355 204.188 223.053 1.00 34.14  ? 267 ASP F CB    1 
ATOM   8796  C  CG    . ASP E 2 198 ? 227.138 203.502 224.162 1.00 40.74  ? 267 ASP F CG    1 
ATOM   8797  O  OD1   . ASP E 2 198 ? 226.574 202.560 224.780 1.00 45.37  ? 267 ASP F OD1   1 
ATOM   8798  O  OD2   . ASP E 2 198 ? 228.270 203.951 224.442 1.00 41.79  ? 267 ASP F OD2   1 
ATOM   8799  N  N     . LYS E 2 199 ? 223.155 205.208 222.407 1.00 25.20  ? 268 LYS F N     1 
ATOM   8800  C  CA    . LYS E 2 199 ? 222.237 205.540 221.327 1.00 25.31  ? 268 LYS F CA    1 
ATOM   8801  C  C     . LYS E 2 199 ? 221.246 206.638 221.709 1.00 24.15  ? 268 LYS F C     1 
ATOM   8802  O  O     . LYS E 2 199 ? 220.434 207.036 220.872 1.00 24.18  ? 268 LYS F O     1 
ATOM   8803  C  CB    . LYS E 2 199 ? 221.482 204.281 220.894 1.00 28.13  ? 268 LYS F CB    1 
ATOM   8804  C  CG    . LYS E 2 199 ? 222.342 203.321 220.096 1.00 32.11  ? 268 LYS F CG    1 
ATOM   8805  C  CD    . LYS E 2 199 ? 222.176 201.870 220.515 1.00 37.36  ? 268 LYS F CD    1 
ATOM   8806  C  CE    . LYS E 2 199 ? 220.857 201.297 220.118 1.00 41.57  ? 268 LYS F CE    1 
ATOM   8807  N  NZ    . LYS E 2 199 ? 220.770 199.868 220.453 1.00 43.79  ? 268 LYS F NZ    1 
ATOM   8808  N  N     . LEU E 2 200 ? 221.277 207.121 222.955 1.00 20.92  ? 269 LEU F N     1 
ATOM   8809  C  CA    . LEU E 2 200 ? 220.362 208.175 223.366 1.00 19.47  ? 269 LEU F CA    1 
ATOM   8810  C  C     . LEU E 2 200 ? 220.662 209.445 222.579 1.00 18.10  ? 269 LEU F C     1 
ATOM   8811  O  O     . LEU E 2 200 ? 221.809 209.878 222.511 1.00 18.84  ? 269 LEU F O     1 
ATOM   8812  C  CB    . LEU E 2 200 ? 220.475 208.444 224.863 1.00 20.71  ? 269 LEU F CB    1 
ATOM   8813  C  CG    . LEU E 2 200 ? 219.783 207.447 225.791 1.00 21.64  ? 269 LEU F CG    1 
ATOM   8814  C  CD1   . LEU E 2 200 ? 220.156 207.759 227.224 1.00 23.45  ? 269 LEU F CD1   1 
ATOM   8815  C  CD2   . LEU E 2 200 ? 218.288 207.494 225.617 1.00 22.39  ? 269 LEU F CD2   1 
ATOM   8816  N  N     . LEU E 2 201 ? 219.623 210.059 222.007 1.00 17.21  ? 270 LEU F N     1 
ATOM   8817  C  CA    . LEU E 2 201 ? 219.796 211.258 221.207 1.00 17.42  ? 270 LEU F CA    1 
ATOM   8818  C  C     . LEU E 2 201 ? 219.814 212.480 222.119 1.00 17.39  ? 270 LEU F C     1 
ATOM   8819  O  O     . LEU E 2 201 ? 218.942 213.346 222.063 1.00 17.90  ? 270 LEU F O     1 
ATOM   8820  C  CB    . LEU E 2 201 ? 218.726 211.323 220.123 1.00 17.66  ? 270 LEU F CB    1 
ATOM   8821  C  CG    . LEU E 2 201 ? 218.849 210.205 219.088 1.00 18.78  ? 270 LEU F CG    1 
ATOM   8822  C  CD1   . LEU E 2 201 ? 217.663 210.177 218.147 1.00 18.72  ? 270 LEU F CD1   1 
ATOM   8823  C  CD2   . LEU E 2 201 ? 220.160 210.350 218.323 1.00 18.64  ? 270 LEU F CD2   1 
ATOM   8824  N  N     . LEU E 2 202 ? 220.850 212.519 222.956 1.00 16.47  ? 271 LEU F N     1 
ATOM   8825  C  CA    . LEU E 2 202 ? 221.131 213.644 223.827 1.00 16.92  ? 271 LEU F CA    1 
ATOM   8826  C  C     . LEU E 2 202 ? 222.642 213.840 223.859 1.00 16.04  ? 271 LEU F C     1 
ATOM   8827  O  O     . LEU E 2 202 ? 223.404 212.941 223.504 1.00 16.77  ? 271 LEU F O     1 
ATOM   8828  C  CB    . LEU E 2 202 ? 220.556 213.427 225.229 1.00 17.13  ? 271 LEU F CB    1 
ATOM   8829  C  CG    . LEU E 2 202 ? 221.027 212.193 226.009 1.00 17.69  ? 271 LEU F CG    1 
ATOM   8830  C  CD1   . LEU E 2 202 ? 222.275 212.434 226.847 1.00 18.38  ? 271 LEU F CD1   1 
ATOM   8831  C  CD2   . LEU E 2 202 ? 219.910 211.708 226.910 1.00 18.55  ? 271 LEU F CD2   1 
ATOM   8832  N  N     . THR E 2 203 ? 223.063 215.034 224.276 1.00 15.63  ? 272 THR F N     1 
ATOM   8833  C  CA    . THR E 2 203 ? 224.478 215.349 224.384 1.00 16.78  ? 272 THR F CA    1 
ATOM   8834  C  C     . THR E 2 203 ? 224.897 215.244 225.845 1.00 17.44  ? 272 THR F C     1 
ATOM   8835  O  O     . THR E 2 203 ? 224.441 216.026 226.676 1.00 18.45  ? 272 THR F O     1 
ATOM   8836  C  CB    . THR E 2 203 ? 224.771 216.745 223.845 1.00 16.95  ? 272 THR F CB    1 
ATOM   8837  O  OG1   . THR E 2 203 ? 224.354 216.823 222.488 1.00 16.65  ? 272 THR F OG1   1 
ATOM   8838  C  CG2   . THR E 2 203 ? 226.253 217.069 223.903 1.00 17.60  ? 272 THR F CG2   1 
ATOM   8839  N  N     . SER E 2 204 ? 225.766 214.273 226.143 1.00 19.46  ? 273 SER F N     1 
ATOM   8840  C  CA    . SER E 2 204 ? 226.338 214.121 227.472 1.00 21.69  ? 273 SER F CA    1 
ATOM   8841  C  C     . SER E 2 204 ? 227.808 214.522 227.417 1.00 24.15  ? 273 SER F C     1 
ATOM   8842  O  O     . SER E 2 204 ? 228.561 213.987 226.605 1.00 26.94  ? 273 SER F O     1 
ATOM   8843  C  CB    . SER E 2 204 ? 226.182 212.716 227.992 1.00 22.14  ? 273 SER F CB    1 
ATOM   8844  O  OG    . SER E 2 204 ? 227.017 211.821 227.277 1.00 23.51  ? 273 SER F OG    1 
ATOM   8845  N  N     . THR E 2 205 ? 228.206 215.469 228.267 1.00 24.31  ? 274 THR F N     1 
ATOM   8846  C  CA    . THR E 2 205 ? 229.569 215.975 228.245 1.00 26.39  ? 274 THR F CA    1 
ATOM   8847  C  C     . THR E 2 205 ? 230.054 216.203 229.668 1.00 27.00  ? 274 THR F C     1 
ATOM   8848  O  O     . THR E 2 205 ? 229.269 216.462 230.576 1.00 24.80  ? 274 THR F O     1 
ATOM   8849  C  CB    . THR E 2 205 ? 229.647 217.265 227.428 1.00 27.93  ? 274 THR F CB    1 
ATOM   8850  O  OG1   . THR E 2 205 ? 231.006 217.699 227.393 1.00 29.51  ? 274 THR F OG1   1 
ATOM   8851  C  CG2   . THR E 2 205 ? 228.794 218.366 228.019 1.00 27.99  ? 274 THR F CG2   1 
ATOM   8852  N  N     . GLU E 2 206 ? 231.377 216.132 229.831 1.00 30.23  ? 275 GLU F N     1 
ATOM   8853  C  CA    . GLU E 2 206 ? 232.030 216.493 231.078 1.00 32.54  ? 275 GLU F CA    1 
ATOM   8854  C  C     . GLU E 2 206 ? 232.061 218.008 231.257 1.00 30.78  ? 275 GLU F C     1 
ATOM   8855  O  O     . GLU E 2 206 ? 232.229 218.483 232.375 1.00 31.40  ? 275 GLU F O     1 
ATOM   8856  C  CB    . GLU E 2 206 ? 233.465 215.973 231.125 1.00 37.49  ? 275 GLU F CB    1 
ATOM   8857  C  CG    . GLU E 2 206 ? 233.570 214.451 231.183 1.00 43.09  ? 275 GLU F CG    1 
ATOM   8858  C  CD    . GLU E 2 206 ? 234.748 213.990 232.024 1.00 51.64  ? 275 GLU F CD    1 
ATOM   8859  O  OE1   . GLU E 2 206 ? 234.866 214.467 233.177 1.00 53.32  ? 275 GLU F OE1   1 
ATOM   8860  O  OE2   . GLU E 2 206 ? 235.554 213.168 231.536 1.00 54.84  ? 275 GLU F OE2   1 
ATOM   8861  N  N     . LYS E 2 207 ? 231.895 218.766 230.169 1.00 32.31  ? 276 LYS F N     1 
ATOM   8862  C  CA    . LYS E 2 207 ? 232.020 220.212 230.223 1.00 35.24  ? 276 LYS F CA    1 
ATOM   8863  C  C     . LYS E 2 207 ? 230.777 220.841 230.845 1.00 34.78  ? 276 LYS F C     1 
ATOM   8864  O  O     . LYS E 2 207 ? 229.679 220.290 230.791 1.00 34.58  ? 276 LYS F O     1 
ATOM   8865  C  CB    . LYS E 2 207 ? 232.246 220.772 228.818 1.00 40.08  ? 276 LYS F CB    1 
ATOM   8866  C  CG    . LYS E 2 207 ? 233.497 220.246 228.140 1.00 44.95  ? 276 LYS F CG    1 
ATOM   8867  C  CD    . LYS E 2 207 ? 233.874 221.037 226.895 1.00 50.00  ? 276 LYS F CD    1 
ATOM   8868  C  CE    . LYS E 2 207 ? 232.790 221.107 225.861 1.00 53.56  ? 276 LYS F CE    1 
ATOM   8869  N  NZ    . LYS E 2 207 ? 232.530 219.824 225.200 1.00 56.78  ? 276 LYS F NZ    1 
ATOM   8870  N  N     . SER E 2 208 ? 230.970 222.023 231.429 1.00 31.74  ? 277 SER F N     1 
ATOM   8871  C  CA    . SER E 2 208 ? 229.884 222.778 232.022 1.00 30.29  ? 277 SER F CA    1 
ATOM   8872  C  C     . SER E 2 208 ? 229.042 223.434 230.929 1.00 29.23  ? 277 SER F C     1 
ATOM   8873  O  O     . SER E 2 208 ? 229.472 223.582 229.789 1.00 29.92  ? 277 SER F O     1 
ATOM   8874  C  CB    . SER E 2 208 ? 230.411 223.804 233.002 1.00 30.17  ? 277 SER F CB    1 
ATOM   8875  O  OG    . SER E 2 208 ? 229.375 224.680 233.424 1.00 29.82  ? 277 SER F OG    1 
ATOM   8876  N  N     . HIS E 2 209 ? 227.836 223.851 231.308 1.00 27.54  ? 278 HIS F N     1 
ATOM   8877  C  CA    . HIS E 2 209 ? 226.949 224.562 230.406 1.00 26.94  ? 278 HIS F CA    1 
ATOM   8878  C  C     . HIS E 2 209 ? 227.521 225.925 230.016 1.00 27.89  ? 278 HIS F C     1 
ATOM   8879  O  O     . HIS E 2 209 ? 227.233 226.424 228.936 1.00 26.56  ? 278 HIS F O     1 
ATOM   8880  C  CB    . HIS E 2 209 ? 225.559 224.714 231.027 1.00 24.69  ? 278 HIS F CB    1 
ATOM   8881  C  CG    . HIS E 2 209 ? 225.590 225.053 232.476 1.00 23.64  ? 278 HIS F CG    1 
ATOM   8882  N  ND1   . HIS E 2 209 ? 225.731 224.087 233.445 1.00 24.87  ? 278 HIS F ND1   1 
ATOM   8883  C  CD2   . HIS E 2 209 ? 225.507 226.218 233.126 1.00 24.76  ? 278 HIS F CD2   1 
ATOM   8884  C  CE1   . HIS E 2 209 ? 225.731 224.668 234.641 1.00 25.01  ? 278 HIS F CE1   1 
ATOM   8885  N  NE2   . HIS E 2 209 ? 225.592 225.966 234.473 1.00 24.78  ? 278 HIS F NE2   1 
ATOM   8886  N  N     . VAL E 2 210 ? 228.324 226.532 230.890 1.00 29.85  ? 279 VAL F N     1 
ATOM   8887  C  CA    . VAL E 2 210 ? 228.918 227.826 230.578 1.00 33.61  ? 279 VAL F CA    1 
ATOM   8888  C  C     . VAL E 2 210 ? 229.929 227.699 229.435 1.00 33.94  ? 279 VAL F C     1 
ATOM   8889  O  O     . VAL E 2 210 ? 230.151 228.657 228.700 1.00 36.36  ? 279 VAL F O     1 
ATOM   8890  C  CB    . VAL E 2 210 ? 229.560 228.445 231.829 1.00 33.62  ? 279 VAL F CB    1 
ATOM   8891  C  CG1   . VAL E 2 210 ? 228.491 228.800 232.852 1.00 34.88  ? 279 VAL F CG1   1 
ATOM   8892  C  CG2   . VAL E 2 210 ? 230.631 227.534 232.422 1.00 34.39  ? 279 VAL F CG2   1 
ATOM   8893  N  N     . ASP E 2 211 ? 230.522 226.512 229.274 1.00 36.58  ? 280 ASP F N     1 
ATOM   8894  C  CA    . ASP E 2 211 ? 231.487 226.276 228.211 1.00 39.67  ? 280 ASP F CA    1 
ATOM   8895  C  C     . ASP E 2 211 ? 230.831 225.989 226.862 1.00 39.05  ? 280 ASP F C     1 
ATOM   8896  O  O     . ASP E 2 211 ? 231.519 226.007 225.843 1.00 41.94  ? 280 ASP F O     1 
ATOM   8897  C  CB    . ASP E 2 211 ? 232.428 225.148 228.582 1.00 42.35  ? 280 ASP F CB    1 
ATOM   8898  C  CG    . ASP E 2 211 ? 233.148 225.378 229.900 1.00 49.08  ? 280 ASP F CG    1 
ATOM   8899  O  OD1   . ASP E 2 211 ? 233.473 226.558 230.184 1.00 51.03  ? 280 ASP F OD1   1 
ATOM   8900  O  OD2   . ASP E 2 211 ? 233.387 224.385 230.620 1.00 49.82  ? 280 ASP F OD2   1 
ATOM   8901  N  N     . LEU E 2 212 ? 229.516 225.722 226.842 1.00 36.27  ? 281 LEU F N     1 
ATOM   8902  C  CA    . LEU E 2 212 ? 228.830 225.340 225.612 1.00 33.55  ? 281 LEU F CA    1 
ATOM   8903  C  C     . LEU E 2 212 ? 227.899 226.437 225.107 1.00 29.97  ? 281 LEU F C     1 
ATOM   8904  O  O     . LEU E 2 212 ? 227.591 226.462 223.917 1.00 32.69  ? 281 LEU F O     1 
ATOM   8905  C  CB    . LEU E 2 212 ? 228.034 224.056 225.830 1.00 34.12  ? 281 LEU F CB    1 
ATOM   8906  C  CG    . LEU E 2 212 ? 228.837 222.797 226.150 1.00 36.68  ? 281 LEU F CG    1 
ATOM   8907  C  CD1   . LEU E 2 212 ? 227.936 221.771 226.809 1.00 37.28  ? 281 LEU F CD1   1 
ATOM   8908  C  CD2   . LEU E 2 212 ? 229.476 222.225 224.901 1.00 37.88  ? 281 LEU F CD2   1 
ATOM   8909  N  N     . PHE E 2 213 ? 227.421 227.309 225.999 1.00 27.38  ? 282 PHE F N     1 
ATOM   8910  C  CA    . PHE E 2 213 ? 226.441 228.311 225.618 1.00 27.62  ? 282 PHE F CA    1 
ATOM   8911  C  C     . PHE E 2 213 ? 226.888 229.679 226.117 1.00 28.75  ? 282 PHE F C     1 
ATOM   8912  O  O     . PHE E 2 213 ? 227.581 229.775 227.129 1.00 28.30  ? 282 PHE F O     1 
ATOM   8913  C  CB    . PHE E 2 213 ? 225.065 227.975 226.199 1.00 25.45  ? 282 PHE F CB    1 
ATOM   8914  C  CG    . PHE E 2 213 ? 224.655 226.538 225.956 1.00 23.36  ? 282 PHE F CG    1 
ATOM   8915  C  CD1   . PHE E 2 213 ? 224.148 226.147 224.724 1.00 22.01  ? 282 PHE F CD1   1 
ATOM   8916  C  CD2   . PHE E 2 213 ? 224.792 225.589 226.958 1.00 21.18  ? 282 PHE F CD2   1 
ATOM   8917  C  CE1   . PHE E 2 213 ? 223.783 224.831 224.507 1.00 21.77  ? 282 PHE F CE1   1 
ATOM   8918  C  CE2   . PHE E 2 213 ? 224.425 224.278 226.733 1.00 21.62  ? 282 PHE F CE2   1 
ATOM   8919  C  CZ    . PHE E 2 213 ? 223.922 223.899 225.510 1.00 20.93  ? 282 PHE F CZ    1 
ATOM   8920  N  N     . PRO E 2 214 ? 226.495 230.767 225.424 1.00 31.05  ? 283 PRO F N     1 
ATOM   8921  C  CA    . PRO E 2 214 ? 226.747 232.112 225.931 1.00 32.60  ? 283 PRO F CA    1 
ATOM   8922  C  C     . PRO E 2 214 ? 226.087 232.308 227.291 1.00 35.71  ? 283 PRO F C     1 
ATOM   8923  O  O     . PRO E 2 214 ? 224.970 231.843 227.525 1.00 38.52  ? 283 PRO F O     1 
ATOM   8924  C  CB    . PRO E 2 214 ? 226.155 233.034 224.871 1.00 33.16  ? 283 PRO F CB    1 
ATOM   8925  C  CG    . PRO E 2 214 ? 226.031 232.175 223.627 1.00 34.05  ? 283 PRO F CG    1 
ATOM   8926  C  CD    . PRO E 2 214 ? 225.815 230.757 224.119 1.00 33.12  ? 283 PRO F CD    1 
ATOM   8927  N  N     . LYS E 2 215 ? 226.769 233.025 228.184 1.00 37.56  ? 284 LYS F N     1 
ATOM   8928  C  CA    . LYS E 2 215 ? 226.285 233.187 229.544 1.00 38.89  ? 284 LYS F CA    1 
ATOM   8929  C  C     . LYS E 2 215 ? 224.993 233.999 229.589 1.00 36.75  ? 284 LYS F C     1 
ATOM   8930  O  O     . LYS E 2 215 ? 224.164 233.774 230.469 1.00 36.65  ? 284 LYS F O     1 
ATOM   8931  C  CB    . LYS E 2 215 ? 227.357 233.817 230.430 1.00 45.26  ? 284 LYS F CB    1 
ATOM   8932  C  CG    . LYS E 2 215 ? 228.575 232.929 230.573 1.00 53.24  ? 284 LYS F CG    1 
ATOM   8933  C  CD    . LYS E 2 215 ? 229.486 233.309 231.734 1.00 58.87  ? 284 LYS F CD    1 
ATOM   8934  C  CE    . LYS E 2 215 ? 228.888 232.999 233.068 1.00 62.28  ? 284 LYS F CE    1 
ATOM   8935  N  NZ    . LYS E 2 215 ? 229.873 233.083 234.150 1.00 63.60  ? 284 LYS F NZ    1 
ATOM   8936  N  N     . ASP E 2 216 ? 224.819 234.939 228.658 1.00 35.41  ? 285 ASP F N     1 
ATOM   8937  C  CA    . ASP E 2 216 ? 223.617 235.759 228.636 1.00 38.15  ? 285 ASP F CA    1 
ATOM   8938  C  C     . ASP E 2 216 ? 222.387 234.931 228.255 1.00 32.71  ? 285 ASP F C     1 
ATOM   8939  O  O     . ASP E 2 216 ? 221.264 235.321 228.564 1.00 32.92  ? 285 ASP F O     1 
ATOM   8940  C  CB    . ASP E 2 216 ? 223.771 236.932 227.686 1.00 45.25  ? 285 ASP F CB    1 
ATOM   8941  C  CG    . ASP E 2 216 ? 224.251 236.532 226.299 1.00 54.63  ? 285 ASP F CG    1 
ATOM   8942  O  OD1   . ASP E 2 216 ? 225.419 236.096 226.208 1.00 59.21  ? 285 ASP F OD1   1 
ATOM   8943  O  OD2   . ASP E 2 216 ? 223.451 236.623 225.340 1.00 56.94  ? 285 ASP F OD2   1 
ATOM   8944  N  N     . SER E 2 217 ? 222.596 233.795 227.578 1.00 29.21  ? 286 SER F N     1 
ATOM   8945  C  CA    . SER E 2 217 ? 221.495 232.953 227.124 1.00 26.83  ? 286 SER F CA    1 
ATOM   8946  C  C     . SER E 2 217 ? 221.086 231.916 228.173 1.00 24.24  ? 286 SER F C     1 
ATOM   8947  O  O     . SER E 2 217 ? 220.098 231.221 227.971 1.00 25.11  ? 286 SER F O     1 
ATOM   8948  C  CB    . SER E 2 217 ? 221.838 232.269 225.825 1.00 25.31  ? 286 SER F CB    1 
ATOM   8949  O  OG    . SER E 2 217 ? 222.727 231.187 226.042 1.00 26.04  ? 286 SER F OG    1 
ATOM   8950  N  N     . ILE E 2 218 ? 221.853 231.781 229.258 1.00 22.96  ? 287 ILE F N     1 
ATOM   8951  C  CA    . ILE E 2 218 ? 221.616 230.747 230.251 1.00 21.81  ? 287 ILE F CA    1 
ATOM   8952  C  C     . ILE E 2 218 ? 220.695 231.279 231.341 1.00 21.41  ? 287 ILE F C     1 
ATOM   8953  O  O     . ILE E 2 218 ? 220.930 232.357 231.880 1.00 23.05  ? 287 ILE F O     1 
ATOM   8954  C  CB    . ILE E 2 218 ? 222.941 230.248 230.841 1.00 22.92  ? 287 ILE F CB    1 
ATOM   8955  C  CG1   . ILE E 2 218 ? 223.741 229.475 229.814 1.00 23.46  ? 287 ILE F CG1   1 
ATOM   8956  C  CG2   . ILE E 2 218 ? 222.692 229.415 232.096 1.00 23.96  ? 287 ILE F CG2   1 
ATOM   8957  C  CD1   . ILE E 2 218 ? 225.147 229.132 230.265 1.00 24.48  ? 287 ILE F CD1   1 
ATOM   8958  N  N     . ILE E 2 219 ? 219.636 230.517 231.642 1.00 19.95  ? 288 ILE F N     1 
ATOM   8959  C  CA    . ILE E 2 219 ? 218.784 230.781 232.787 1.00 19.76  ? 288 ILE F CA    1 
ATOM   8960  C  C     . ILE E 2 219 ? 218.817 229.538 233.660 1.00 19.60  ? 288 ILE F C     1 
ATOM   8961  O  O     . ILE E 2 219 ? 218.396 228.471 233.224 1.00 19.60  ? 288 ILE F O     1 
ATOM   8962  C  CB    . ILE E 2 219 ? 217.345 231.138 232.386 1.00 20.69  ? 288 ILE F CB    1 
ATOM   8963  C  CG1   . ILE E 2 219 ? 217.287 232.474 231.668 1.00 20.99  ? 288 ILE F CG1   1 
ATOM   8964  C  CG2   . ILE E 2 219 ? 216.419 231.109 233.603 1.00 21.33  ? 288 ILE F CG2   1 
ATOM   8965  C  CD1   . ILE E 2 219 ? 215.911 232.823 231.159 1.00 21.67  ? 288 ILE F CD1   1 
ATOM   8966  N  N     . TYR E 2 220 ? 219.325 229.689 234.883 1.00 18.25  ? 289 TYR F N     1 
ATOM   8967  C  CA    . TYR E 2 220 ? 219.423 228.586 235.823 1.00 17.32  ? 289 TYR F CA    1 
ATOM   8968  C  C     . TYR E 2 220 ? 218.159 228.530 236.676 1.00 17.35  ? 289 TYR F C     1 
ATOM   8969  O  O     . TYR E 2 220 ? 217.889 229.440 237.444 1.00 17.92  ? 289 TYR F O     1 
ATOM   8970  C  CB    . TYR E 2 220 ? 220.667 228.723 236.698 1.00 17.28  ? 289 TYR F CB    1 
ATOM   8971  C  CG    . TYR E 2 220 ? 221.224 227.399 237.186 1.00 18.08  ? 289 TYR F CG    1 
ATOM   8972  C  CD1   . TYR E 2 220 ? 222.524 227.013 236.877 1.00 19.05  ? 289 TYR F CD1   1 
ATOM   8973  C  CD2   . TYR E 2 220 ? 220.436 226.521 237.913 1.00 18.85  ? 289 TYR F CD2   1 
ATOM   8974  C  CE1   . TYR E 2 220 ? 223.030 225.799 237.304 1.00 19.15  ? 289 TYR F CE1   1 
ATOM   8975  C  CE2   . TYR E 2 220 ? 220.926 225.296 238.335 1.00 19.27  ? 289 TYR F CE2   1 
ATOM   8976  C  CZ    . TYR E 2 220 ? 222.231 224.942 238.040 1.00 18.65  ? 289 TYR F CZ    1 
ATOM   8977  O  OH    . TYR E 2 220 ? 222.737 223.747 238.462 1.00 18.81  ? 289 TYR F OH    1 
ATOM   8978  N  N     . LEU E 2 221 ? 217.373 227.459 236.520 1.00 16.82  ? 290 LEU F N     1 
ATOM   8979  C  CA    . LEU E 2 221 ? 216.121 227.318 237.241 1.00 16.44  ? 290 LEU F CA    1 
ATOM   8980  C  C     . LEU E 2 221 ? 216.407 226.825 238.656 1.00 17.37  ? 290 LEU F C     1 
ATOM   8981  O  O     . LEU E 2 221 ? 217.146 225.863 238.846 1.00 17.40  ? 290 LEU F O     1 
ATOM   8982  C  CB    . LEU E 2 221 ? 215.198 226.351 236.513 1.00 16.91  ? 290 LEU F CB    1 
ATOM   8983  C  CG    . LEU E 2 221 ? 214.634 226.831 235.178 1.00 17.15  ? 290 LEU F CG    1 
ATOM   8984  C  CD1   . LEU E 2 221 ? 213.940 225.690 234.456 1.00 17.31  ? 290 LEU F CD1   1 
ATOM   8985  C  CD2   . LEU E 2 221 ? 213.690 227.994 235.403 1.00 18.14  ? 290 LEU F CD2   1 
ATOM   8986  N  N     . THR E 2 222 ? 215.803 227.494 239.637 1.00 18.04  ? 291 THR F N     1 
ATOM   8987  C  CA    . THR E 2 222 ? 215.908 227.077 241.026 1.00 20.78  ? 291 THR F CA    1 
ATOM   8988  C  C     . THR E 2 222 ? 214.777 227.735 241.801 1.00 19.95  ? 291 THR F C     1 
ATOM   8989  O  O     . THR E 2 222 ? 214.471 228.901 241.579 1.00 19.79  ? 291 THR F O     1 
ATOM   8990  C  CB    . THR E 2 222 ? 217.281 227.434 241.598 1.00 23.03  ? 291 THR F CB    1 
ATOM   8991  O  OG1   . THR E 2 222 ? 217.341 227.016 242.959 1.00 27.35  ? 291 THR F OG1   1 
ATOM   8992  C  CG2   . THR E 2 222 ? 217.582 228.914 241.521 1.00 24.13  ? 291 THR F CG2   1 
ATOM   8993  N  N     . ALA E 2 223 ? 214.160 226.978 242.706 1.00 20.68  ? 292 ALA F N     1 
ATOM   8994  C  CA    . ALA E 2 223 ? 213.048 227.486 243.497 1.00 22.01  ? 292 ALA F CA    1 
ATOM   8995  C  C     . ALA E 2 223 ? 213.496 228.600 244.446 1.00 23.23  ? 292 ALA F C     1 
ATOM   8996  O  O     . ALA E 2 223 ? 212.669 229.403 244.866 1.00 25.12  ? 292 ALA F O     1 
ATOM   8997  C  CB    . ALA E 2 223 ? 212.395 226.363 244.261 1.00 22.25  ? 292 ALA F CB    1 
ATOM   8998  N  N     . ASP E 2 224 ? 214.790 228.667 244.769 1.00 26.69  ? 293 ASP F N     1 
ATOM   8999  C  CA    . ASP E 2 224 ? 215.302 229.686 245.676 1.00 29.78  ? 293 ASP F CA    1 
ATOM   9000  C  C     . ASP E 2 224 ? 215.574 231.014 244.973 1.00 31.26  ? 293 ASP F C     1 
ATOM   9001  O  O     . ASP E 2 224 ? 215.953 231.983 245.628 1.00 33.40  ? 293 ASP F O     1 
ATOM   9002  C  CB    . ASP E 2 224 ? 216.568 229.207 246.360 1.00 31.97  ? 293 ASP F CB    1 
ATOM   9003  C  CG    . ASP E 2 224 ? 216.378 227.917 247.140 1.00 38.19  ? 293 ASP F CG    1 
ATOM   9004  O  OD1   . ASP E 2 224 ? 215.482 227.896 248.011 1.00 40.67  ? 293 ASP F OD1   1 
ATOM   9005  O  OD2   . ASP E 2 224 ? 217.104 226.934 246.848 1.00 42.77  ? 293 ASP F OD2   1 
ATOM   9006  N  N     . SER E 2 225 ? 215.406 231.064 243.649 1.00 30.14  ? 294 SER F N     1 
ATOM   9007  C  CA    . SER E 2 225 ? 215.718 232.263 242.889 1.00 30.04  ? 294 SER F CA    1 
ATOM   9008  C  C     . SER E 2 225 ? 214.797 233.404 243.310 1.00 31.36  ? 294 SER F C     1 
ATOM   9009  O  O     . SER E 2 225 ? 213.613 233.189 243.560 1.00 32.48  ? 294 SER F O     1 
ATOM   9010  C  CB    . SER E 2 225 ? 215.612 232.005 241.410 1.00 29.34  ? 294 SER F CB    1 
ATOM   9011  O  OG    . SER E 2 225 ? 215.605 233.221 240.677 1.00 29.25  ? 294 SER F OG    1 
ATOM   9012  N  N     . PRO E 2 226 ? 215.300 234.656 243.387 1.00 33.69  ? 295 PRO F N     1 
ATOM   9013  C  CA    . PRO E 2 226 ? 214.422 235.793 243.649 1.00 36.07  ? 295 PRO F CA    1 
ATOM   9014  C  C     . PRO E 2 226 ? 213.580 236.229 242.451 1.00 36.73  ? 295 PRO F C     1 
ATOM   9015  O  O     . PRO E 2 226 ? 212.569 236.893 242.637 1.00 41.56  ? 295 PRO F O     1 
ATOM   9016  C  CB    . PRO E 2 226 ? 215.403 236.883 244.086 1.00 36.48  ? 295 PRO F CB    1 
ATOM   9017  C  CG    . PRO E 2 226 ? 216.666 236.558 243.329 1.00 37.60  ? 295 PRO F CG    1 
ATOM   9018  C  CD    . PRO E 2 226 ? 216.716 235.041 243.251 1.00 34.95  ? 295 PRO F CD    1 
ATOM   9019  N  N     . ASN E 2 227 ? 213.995 235.859 241.234 1.00 34.35  ? 296 ASN F N     1 
ATOM   9020  C  CA    . ASN E 2 227 ? 213.297 236.262 240.026 1.00 32.17  ? 296 ASN F CA    1 
ATOM   9021  C  C     . ASN E 2 227 ? 212.260 235.204 239.665 1.00 31.94  ? 296 ASN F C     1 
ATOM   9022  O  O     . ASN E 2 227 ? 212.598 234.039 239.502 1.00 33.10  ? 296 ASN F O     1 
ATOM   9023  C  CB    . ASN E 2 227 ? 214.264 236.472 238.868 1.00 32.70  ? 296 ASN F CB    1 
ATOM   9024  C  CG    . ASN E 2 227 ? 215.540 237.149 239.308 1.00 33.99  ? 296 ASN F CG    1 
ATOM   9025  O  OD1   . ASN E 2 227 ? 215.502 238.294 239.770 1.00 37.72  ? 296 ASN F OD1   1 
ATOM   9026  N  ND2   . ASN E 2 227 ? 216.669 236.467 239.174 1.00 34.39  ? 296 ASN F ND2   1 
ATOM   9027  N  N     . VAL E 2 228 ? 210.998 235.619 239.550 1.00 29.75  ? 297 VAL F N     1 
ATOM   9028  C  CA    . VAL E 2 228 ? 209.924 234.707 239.217 1.00 28.59  ? 297 VAL F CA    1 
ATOM   9029  C  C     . VAL E 2 228 ? 209.783 234.650 237.699 1.00 28.42  ? 297 VAL F C     1 
ATOM   9030  O  O     . VAL E 2 228 ? 209.656 235.676 237.038 1.00 29.35  ? 297 VAL F O     1 
ATOM   9031  C  CB    . VAL E 2 228 ? 208.608 235.142 239.878 1.00 28.09  ? 297 VAL F CB    1 
ATOM   9032  C  CG1   . VAL E 2 228 ? 207.450 234.268 239.431 1.00 27.92  ? 297 VAL F CG1   1 
ATOM   9033  C  CG2   . VAL E 2 228 ? 208.727 235.147 241.392 1.00 29.29  ? 297 VAL F CG2   1 
ATOM   9034  N  N     . MET E 2 229 ? 209.786 233.434 237.156 1.00 27.20  ? 298 MET F N     1 
ATOM   9035  C  CA    . MET E 2 229 ? 209.636 233.254 235.724 1.00 27.19  ? 298 MET F CA    1 
ATOM   9036  C  C     . MET E 2 229 ? 208.225 233.664 235.307 1.00 26.96  ? 298 MET F C     1 
ATOM   9037  O  O     . MET E 2 229 ? 207.243 233.215 235.897 1.00 27.91  ? 298 MET F O     1 
ATOM   9038  C  CB    . MET E 2 229 ? 209.912 231.793 235.353 1.00 28.32  ? 298 MET F CB    1 
ATOM   9039  C  CG    . MET E 2 229 ? 209.655 231.440 233.908 1.00 29.24  ? 298 MET F CG    1 
ATOM   9040  S  SD    . MET E 2 229 ? 210.046 229.699 233.619 1.00 32.32  ? 298 MET F SD    1 
ATOM   9041  C  CE    . MET E 2 229 ? 210.065 229.674 231.824 1.00 30.44  ? 298 MET F CE    1 
ATOM   9042  N  N     . THR E 2 230 ? 208.134 234.484 234.251 1.00 27.26  ? 299 THR F N     1 
ATOM   9043  C  CA    . THR E 2 230 ? 206.849 234.955 233.745 1.00 28.43  ? 299 THR F CA    1 
ATOM   9044  C  C     . THR E 2 230 ? 206.482 234.270 232.433 1.00 26.92  ? 299 THR F C     1 
ATOM   9045  O  O     . THR E 2 230 ? 205.324 233.890 232.244 1.00 27.21  ? 299 THR F O     1 
ATOM   9046  C  CB    . THR E 2 230 ? 206.848 236.473 233.564 1.00 30.35  ? 299 THR F CB    1 
ATOM   9047  O  OG1   . THR E 2 230 ? 208.032 236.868 232.877 1.00 31.89  ? 299 THR F OG1   1 
ATOM   9048  C  CG2   . THR E 2 230 ? 206.820 237.193 234.896 1.00 31.24  ? 299 THR F CG2   1 
ATOM   9049  N  N     . THR E 2 231 ? 207.450 234.154 231.517 1.00 25.97  ? 300 THR F N     1 
ATOM   9050  C  CA    . THR E 2 231 ? 207.186 233.540 230.226 1.00 27.38  ? 300 THR F CA    1 
ATOM   9051  C  C     . THR E 2 231 ? 208.334 232.609 229.860 1.00 24.34  ? 300 THR F C     1 
ATOM   9052  O  O     . THR E 2 231 ? 209.468 232.803 230.285 1.00 24.58  ? 300 THR F O     1 
ATOM   9053  C  CB    . THR E 2 231 ? 206.977 234.613 229.155 1.00 29.45  ? 300 THR F CB    1 
ATOM   9054  O  OG1   . THR E 2 231 ? 206.653 233.983 227.917 1.00 31.18  ? 300 THR F OG1   1 
ATOM   9055  C  CG2   . THR E 2 231 ? 208.227 235.438 228.944 1.00 31.18  ? 300 THR F CG2   1 
ATOM   9056  N  N     . PHE E 2 232 ? 208.009 231.608 229.046 1.00 22.77  ? 301 PHE F N     1 
ATOM   9057  C  CA    . PHE E 2 232 ? 209.010 230.708 228.505 1.00 21.00  ? 301 PHE F CA    1 
ATOM   9058  C  C     . PHE E 2 232 ? 209.668 231.377 227.307 1.00 20.66  ? 301 PHE F C     1 
ATOM   9059  O  O     . PHE E 2 232 ? 208.982 231.825 226.391 1.00 22.67  ? 301 PHE F O     1 
ATOM   9060  C  CB    . PHE E 2 232 ? 208.383 229.379 228.087 1.00 19.82  ? 301 PHE F CB    1 
ATOM   9061  C  CG    . PHE E 2 232 ? 209.397 228.380 227.557 1.00 18.60  ? 301 PHE F CG    1 
ATOM   9062  C  CD1   . PHE E 2 232 ? 210.076 227.529 228.424 1.00 17.81  ? 301 PHE F CD1   1 
ATOM   9063  C  CD2   . PHE E 2 232 ? 209.684 228.317 226.202 1.00 17.45  ? 301 PHE F CD2   1 
ATOM   9064  C  CE1   . PHE E 2 232 ? 211.006 226.628 227.939 1.00 17.37  ? 301 PHE F CE1   1 
ATOM   9065  C  CE2   . PHE E 2 232 ? 210.618 227.411 225.720 1.00 18.15  ? 301 PHE F CE2   1 
ATOM   9066  C  CZ    . PHE E 2 232 ? 211.276 226.570 226.589 1.00 17.60  ? 301 PHE F CZ    1 
ATOM   9067  N  N     . ARG E 2 233 ? 211.000 231.447 227.326 1.00 20.87  ? 302 ARG F N     1 
ATOM   9068  C  CA    . ARG E 2 233 ? 211.756 232.097 226.273 1.00 22.60  ? 302 ARG F CA    1 
ATOM   9069  C  C     . ARG E 2 233 ? 212.459 231.034 225.439 1.00 22.19  ? 302 ARG F C     1 
ATOM   9070  O  O     . ARG E 2 233 ? 213.196 230.205 225.969 1.00 21.74  ? 302 ARG F O     1 
ATOM   9071  C  CB    . ARG E 2 233 ? 212.763 233.081 226.874 1.00 26.43  ? 302 ARG F CB    1 
ATOM   9072  C  CG    . ARG E 2 233 ? 212.142 234.410 227.278 1.00 30.88  ? 302 ARG F CG    1 
ATOM   9073  C  CD    . ARG E 2 233 ? 213.148 235.336 227.908 1.00 35.10  ? 302 ARG F CD    1 
ATOM   9074  N  NE    . ARG E 2 233 ? 213.250 235.114 229.354 1.00 38.11  ? 302 ARG F NE    1 
ATOM   9075  C  CZ    . ARG E 2 233 ? 214.060 235.794 230.159 1.00 42.25  ? 302 ARG F CZ    1 
ATOM   9076  N  NH1   . ARG E 2 233 ? 214.879 236.711 229.660 1.00 44.69  ? 302 ARG F NH1   1 
ATOM   9077  N  NH2   . ARG E 2 233 ? 214.054 235.555 231.458 1.00 41.39  ? 302 ARG F NH2   1 
ATOM   9078  N  N     . HIS E 2 234 ? 212.214 231.066 224.130 1.00 22.46  ? 303 HIS F N     1 
ATOM   9079  C  CA    . HIS E 2 234 ? 212.738 230.070 223.209 1.00 21.74  ? 303 HIS F CA    1 
ATOM   9080  C  C     . HIS E 2 234 ? 214.199 230.314 222.853 1.00 21.82  ? 303 HIS F C     1 
ATOM   9081  O  O     . HIS E 2 234 ? 214.850 229.416 222.332 1.00 22.99  ? 303 HIS F O     1 
ATOM   9082  C  CB    . HIS E 2 234 ? 211.877 230.032 221.947 1.00 21.26  ? 303 HIS F CB    1 
ATOM   9083  C  CG    . HIS E 2 234 ? 210.519 229.452 222.185 1.00 22.13  ? 303 HIS F CG    1 
ATOM   9084  N  ND1   . HIS E 2 234 ? 209.461 230.230 222.596 1.00 22.34  ? 303 HIS F ND1   1 
ATOM   9085  C  CD2   . HIS E 2 234 ? 210.043 228.199 222.086 1.00 21.81  ? 303 HIS F CD2   1 
ATOM   9086  C  CE1   . HIS E 2 234 ? 208.389 229.465 222.727 1.00 21.76  ? 303 HIS F CE1   1 
ATOM   9087  N  NE2   . HIS E 2 234 ? 208.721 228.230 222.424 1.00 21.77  ? 303 HIS F NE2   1 
ATOM   9088  N  N     . ASP E 2 235 ? 214.714 231.513 223.128 1.00 24.34  ? 304 ASP F N     1 
ATOM   9089  C  CA    . ASP E 2 235 ? 216.096 231.850 222.818 1.00 26.30  ? 304 ASP F CA    1 
ATOM   9090  C  C     . ASP E 2 235 ? 217.003 231.643 224.031 1.00 25.88  ? 304 ASP F C     1 
ATOM   9091  O  O     . ASP E 2 235 ? 218.179 231.992 223.981 1.00 29.08  ? 304 ASP F O     1 
ATOM   9092  C  CB    . ASP E 2 235 ? 216.181 233.297 222.360 1.00 30.07  ? 304 ASP F CB    1 
ATOM   9093  C  CG    . ASP E 2 235 ? 215.849 234.310 223.441 1.00 33.38  ? 304 ASP F CG    1 
ATOM   9094  O  OD1   . ASP E 2 235 ? 214.683 234.341 223.886 1.00 36.72  ? 304 ASP F OD1   1 
ATOM   9095  O  OD2   . ASP E 2 235 ? 216.773 235.045 223.843 1.00 41.63  ? 304 ASP F OD2   1 
ATOM   9096  N  N     . LYS E 2 236 ? 216.464 231.091 225.124 1.00 24.02  ? 305 LYS F N     1 
ATOM   9097  C  CA    . LYS E 2 236 ? 217.224 230.901 226.351 1.00 22.70  ? 305 LYS F CA    1 
ATOM   9098  C  C     . LYS E 2 236 ? 217.526 229.421 226.555 1.00 20.64  ? 305 LYS F C     1 
ATOM   9099  O  O     . LYS E 2 236 ? 216.797 228.547 226.079 1.00 21.96  ? 305 LYS F O     1 
ATOM   9100  C  CB    . LYS E 2 236 ? 216.439 231.443 227.546 1.00 25.95  ? 305 LYS F CB    1 
ATOM   9101  C  CG    . LYS E 2 236 ? 216.406 232.960 227.623 1.00 28.17  ? 305 LYS F CG    1 
ATOM   9102  C  CD    . LYS E 2 236 ? 217.794 233.546 227.840 1.00 30.68  ? 305 LYS F CD    1 
ATOM   9103  C  CE    . LYS E 2 236 ? 217.759 234.927 228.414 1.00 33.56  ? 305 LYS F CE    1 
ATOM   9104  N  NZ    . LYS E 2 236 ? 217.641 235.940 227.368 1.00 35.67  ? 305 LYS F NZ    1 
ATOM   9105  N  N     . VAL E 2 237 ? 218.624 229.158 227.261 1.00 17.51  ? 306 VAL F N     1 
ATOM   9106  C  CA    . VAL E 2 237 ? 219.016 227.815 227.623 1.00 15.86  ? 306 VAL F CA    1 
ATOM   9107  C  C     . VAL E 2 237 ? 218.743 227.633 229.111 1.00 15.47  ? 306 VAL F C     1 
ATOM   9108  O  O     . VAL E 2 237 ? 219.485 228.143 229.949 1.00 15.03  ? 306 VAL F O     1 
ATOM   9109  C  CB    . VAL E 2 237 ? 220.490 227.559 227.286 1.00 16.07  ? 306 VAL F CB    1 
ATOM   9110  C  CG1   . VAL E 2 237 ? 220.925 226.178 227.735 1.00 16.06  ? 306 VAL F CG1   1 
ATOM   9111  C  CG2   . VAL E 2 237 ? 220.751 227.743 225.800 1.00 15.91  ? 306 VAL F CG2   1 
ATOM   9112  N  N     . TYR E 2 238 ? 217.691 226.879 229.420 1.00 14.36  ? 307 TYR F N     1 
ATOM   9113  C  CA    . TYR E 2 238 ? 217.338 226.609 230.800 1.00 14.15  ? 307 TYR F CA    1 
ATOM   9114  C  C     . TYR E 2 238 ? 218.201 225.484 231.347 1.00 13.65  ? 307 TYR F C     1 
ATOM   9115  O  O     . TYR E 2 238 ? 218.483 224.512 230.654 1.00 12.96  ? 307 TYR F O     1 
ATOM   9116  C  CB    . TYR E 2 238 ? 215.856 226.278 230.934 1.00 14.38  ? 307 TYR F CB    1 
ATOM   9117  C  CG    . TYR E 2 238 ? 214.949 227.441 230.603 1.00 15.17  ? 307 TYR F CG    1 
ATOM   9118  C  CD1   . TYR E 2 238 ? 214.691 228.440 231.536 1.00 15.99  ? 307 TYR F CD1   1 
ATOM   9119  C  CD2   . TYR E 2 238 ? 214.393 227.559 229.337 1.00 16.09  ? 307 TYR F CD2   1 
ATOM   9120  C  CE1   . TYR E 2 238 ? 213.867 229.504 231.229 1.00 16.44  ? 307 TYR F CE1   1 
ATOM   9121  C  CE2   . TYR E 2 238 ? 213.576 228.627 229.015 1.00 16.67  ? 307 TYR F CE2   1 
ATOM   9122  C  CZ    . TYR E 2 238 ? 213.314 229.598 229.964 1.00 17.00  ? 307 TYR F CZ    1 
ATOM   9123  O  OH    . TYR E 2 238 ? 212.502 230.645 229.647 1.00 17.91  ? 307 TYR F OH    1 
ATOM   9124  N  N     . VAL E 2 239 ? 218.579 225.626 232.619 1.00 13.60  ? 308 VAL F N     1 
ATOM   9125  C  CA    . VAL E 2 239 ? 219.441 224.667 233.278 1.00 14.76  ? 308 VAL F CA    1 
ATOM   9126  C  C     . VAL E 2 239 ? 218.693 224.136 234.490 1.00 15.15  ? 308 VAL F C     1 
ATOM   9127  O  O     . VAL E 2 239 ? 218.215 224.905 235.315 1.00 16.69  ? 308 VAL F O     1 
ATOM   9128  C  CB    . VAL E 2 239 ? 220.801 225.263 233.685 1.00 14.86  ? 308 VAL F CB    1 
ATOM   9129  C  CG1   . VAL E 2 239 ? 221.710 224.206 234.277 1.00 14.50  ? 308 VAL F CG1   1 
ATOM   9130  C  CG2   . VAL E 2 239 ? 221.496 225.915 232.505 1.00 14.87  ? 308 VAL F CG2   1 
ATOM   9131  N  N     . ILE E 2 240 ? 218.625 222.808 234.593 1.00 15.99  ? 309 ILE F N     1 
ATOM   9132  C  CA    . ILE E 2 240 ? 217.981 222.141 235.709 1.00 16.98  ? 309 ILE F CA    1 
ATOM   9133  C  C     . ILE E 2 240 ? 219.056 221.383 236.472 1.00 16.98  ? 309 ILE F C     1 
ATOM   9134  O  O     . ILE E 2 240 ? 219.823 220.624 235.883 1.00 18.02  ? 309 ILE F O     1 
ATOM   9135  C  CB    . ILE E 2 240 ? 216.855 221.210 235.219 1.00 17.98  ? 309 ILE F CB    1 
ATOM   9136  C  CG1   . ILE E 2 240 ? 215.797 221.975 234.443 1.00 19.04  ? 309 ILE F CG1   1 
ATOM   9137  C  CG2   . ILE E 2 240 ? 216.238 220.456 236.386 1.00 19.10  ? 309 ILE F CG2   1 
ATOM   9138  C  CD1   . ILE E 2 240 ? 214.803 221.079 233.724 1.00 19.53  ? 309 ILE F CD1   1 
ATOM   9139  N  N     . GLY E 2 241 ? 219.078 221.569 237.792 1.00 17.73  ? 310 GLY F N     1 
ATOM   9140  C  CA    . GLY E 2 241 ? 220.013 220.844 238.632 1.00 17.69  ? 310 GLY F CA    1 
ATOM   9141  C  C     . GLY E 2 241 ? 219.566 219.410 238.870 1.00 18.55  ? 310 GLY F C     1 
ATOM   9142  O  O     . GLY E 2 241 ? 218.495 219.178 239.423 1.00 19.83  ? 310 GLY F O     1 
ATOM   9143  N  N     . SER E 2 242 ? 220.400 218.447 238.464 1.00 19.70  ? 311 SER F N     1 
ATOM   9144  C  CA    . SER E 2 242 ? 220.131 217.039 238.707 1.00 20.16  ? 311 SER F CA    1 
ATOM   9145  C  C     . SER E 2 242 ? 220.468 216.713 240.160 1.00 21.31  ? 311 SER F C     1 
ATOM   9146  O  O     . SER E 2 242 ? 221.518 216.141 240.457 1.00 22.16  ? 311 SER F O     1 
ATOM   9147  C  CB    . SER E 2 242 ? 220.893 216.165 237.751 1.00 21.02  ? 311 SER F CB    1 
ATOM   9148  O  OG    . SER E 2 242 ? 220.607 216.533 236.408 1.00 20.40  ? 311 SER F OG    1 
ATOM   9149  N  N     . PHE E 2 243 ? 219.558 217.092 241.055 1.00 22.35  ? 312 PHE F N     1 
ATOM   9150  C  CA    . PHE E 2 243 ? 219.845 217.088 242.477 1.00 24.28  ? 312 PHE F CA    1 
ATOM   9151  C  C     . PHE E 2 243 ? 218.574 216.726 243.234 1.00 24.42  ? 312 PHE F C     1 
ATOM   9152  O  O     . PHE E 2 243 ? 217.692 217.563 243.409 1.00 27.26  ? 312 PHE F O     1 
ATOM   9153  C  CB    . PHE E 2 243 ? 220.373 218.463 242.901 1.00 25.28  ? 312 PHE F CB    1 
ATOM   9154  C  CG    . PHE E 2 243 ? 220.797 218.561 244.355 1.00 26.75  ? 312 PHE F CG    1 
ATOM   9155  C  CD1   . PHE E 2 243 ? 221.296 217.457 245.032 1.00 27.01  ? 312 PHE F CD1   1 
ATOM   9156  C  CD2   . PHE E 2 243 ? 220.707 219.766 245.037 1.00 28.50  ? 312 PHE F CD2   1 
ATOM   9157  C  CE1   . PHE E 2 243 ? 221.695 217.555 246.358 1.00 28.84  ? 312 PHE F CE1   1 
ATOM   9158  C  CE2   . PHE E 2 243 ? 221.107 219.860 246.363 1.00 29.28  ? 312 PHE F CE2   1 
ATOM   9159  C  CZ    . PHE E 2 243 ? 221.609 218.758 247.023 1.00 29.12  ? 312 PHE F CZ    1 
ATOM   9160  N  N     . VAL E 2 244 ? 218.494 215.474 243.681 1.00 23.79  ? 313 VAL F N     1 
ATOM   9161  C  CA    . VAL E 2 244 ? 217.398 215.034 244.521 1.00 26.62  ? 313 VAL F CA    1 
ATOM   9162  C  C     . VAL E 2 244 ? 217.863 215.130 245.969 1.00 29.71  ? 313 VAL F C     1 
ATOM   9163  O  O     . VAL E 2 244 ? 218.568 214.252 246.448 1.00 34.28  ? 313 VAL F O     1 
ATOM   9164  C  CB    . VAL E 2 244 ? 216.942 213.607 244.166 1.00 26.12  ? 313 VAL F CB    1 
ATOM   9165  C  CG1   . VAL E 2 244 ? 215.979 213.041 245.203 1.00 26.29  ? 313 VAL F CG1   1 
ATOM   9166  C  CG2   . VAL E 2 244 ? 216.319 213.559 242.782 1.00 25.08  ? 313 VAL F CG2   1 
ATOM   9167  N  N     . ASP E 2 245 ? 217.487 216.216 246.643 1.00 32.21  ? 314 ASP F N     1 
ATOM   9168  C  CA    . ASP E 2 245 ? 217.914 216.457 248.016 1.00 37.79  ? 314 ASP F CA    1 
ATOM   9169  C  C     . ASP E 2 245 ? 216.779 216.101 248.975 1.00 40.56  ? 314 ASP F C     1 
ATOM   9170  O  O     . ASP E 2 245 ? 216.044 216.974 249.432 1.00 42.06  ? 314 ASP F O     1 
ATOM   9171  C  CB    . ASP E 2 245 ? 218.383 217.893 248.189 1.00 39.47  ? 314 ASP F CB    1 
ATOM   9172  C  CG    . ASP E 2 245 ? 217.329 218.923 247.819 1.00 43.07  ? 314 ASP F CG    1 
ATOM   9173  O  OD1   . ASP E 2 245 ? 216.653 218.704 246.791 1.00 47.94  ? 314 ASP F OD1   1 
ATOM   9174  O  OD2   . ASP E 2 245 ? 217.180 219.916 248.558 1.00 46.69  ? 314 ASP F OD2   1 
ATOM   9175  N  N     . LYS E 2 246 ? 216.631 214.805 249.272 1.00 42.21  ? 315 LYS F N     1 
ATOM   9176  C  CA    . LYS E 2 246 ? 215.714 214.377 250.319 1.00 42.75  ? 315 LYS F CA    1 
ATOM   9177  C  C     . LYS E 2 246 ? 216.144 214.986 251.654 1.00 43.11  ? 315 LYS F C     1 
ATOM   9178  O  O     . LYS E 2 246 ? 215.308 215.452 252.427 1.00 42.00  ? 315 LYS F O     1 
ATOM   9179  C  CB    . LYS E 2 246 ? 215.668 212.849 250.403 1.00 44.76  ? 315 LYS F CB    1 
ATOM   9180  C  CG    . LYS E 2 246 ? 215.209 212.160 249.132 1.00 46.35  ? 315 LYS F CG    1 
ATOM   9181  C  CD    . LYS E 2 246 ? 213.851 212.639 248.647 1.00 47.45  ? 315 LYS F CD    1 
ATOM   9182  C  CE    . LYS E 2 246 ? 212.740 212.328 249.610 1.00 49.38  ? 315 LYS F CE    1 
ATOM   9183  N  NZ    . LYS E 2 246 ? 212.509 210.885 249.741 1.00 48.70  ? 315 LYS F NZ    1 
ATOM   9184  N  N     . SER E 2 247 ? 217.455 214.965 251.917 1.00 44.60  ? 316 SER F N     1 
ATOM   9185  C  CA    . SER E 2 247 ? 218.057 215.783 252.957 1.00 46.96  ? 316 SER F CA    1 
ATOM   9186  C  C     . SER E 2 247 ? 218.219 217.189 252.398 1.00 45.41  ? 316 SER F C     1 
ATOM   9187  O  O     . SER E 2 247 ? 219.215 217.478 251.744 1.00 44.98  ? 316 SER F O     1 
ATOM   9188  C  CB    . SER E 2 247 ? 219.380 215.212 253.415 1.00 46.87  ? 316 SER F CB    1 
ATOM   9189  O  OG    . SER E 2 247 ? 219.205 213.935 254.014 1.00 48.91  ? 316 SER F OG    1 
ATOM   9190  N  N     . MET E 2 248 ? 217.213 218.036 252.634 1.00 47.43  ? 317 MET F N     1 
ATOM   9191  C  CA    . MET E 2 248 ? 217.103 219.317 251.953 1.00 49.17  ? 317 MET F CA    1 
ATOM   9192  C  C     . MET E 2 248 ? 218.325 220.190 252.226 1.00 48.66  ? 317 MET F C     1 
ATOM   9193  O  O     . MET E 2 248 ? 218.762 220.335 253.367 1.00 51.64  ? 317 MET F O     1 
ATOM   9194  C  CB    . MET E 2 248 ? 215.831 220.061 252.370 1.00 53.33  ? 317 MET F CB    1 
ATOM   9195  C  CG    . MET E 2 248 ? 214.678 219.853 251.410 1.00 59.01  ? 317 MET F CG    1 
ATOM   9196  S  SD    . MET E 2 248 ? 213.173 220.713 251.911 1.00 63.19  ? 317 MET F SD    1 
ATOM   9197  C  CE    . MET E 2 248 ? 212.776 219.777 253.394 1.00 61.15  ? 317 MET F CE    1 
ATOM   9198  N  N     . GLN E 2 249 ? 218.866 220.765 251.144 1.00 45.12  ? 318 GLN F N     1 
ATOM   9199  C  CA    . GLN E 2 249 ? 220.010 221.656 251.188 1.00 45.08  ? 318 GLN F CA    1 
ATOM   9200  C  C     . GLN E 2 249 ? 219.656 222.914 250.410 1.00 45.48  ? 318 GLN F C     1 
ATOM   9201  O  O     . GLN E 2 249 ? 220.063 223.071 249.257 1.00 43.77  ? 318 GLN F O     1 
ATOM   9202  C  CB    . GLN E 2 249 ? 221.237 220.963 250.603 1.00 44.68  ? 318 GLN F CB    1 
ATOM   9203  C  CG    . GLN E 2 249 ? 221.766 219.844 251.493 1.00 44.39  ? 318 GLN F CG    1 
ATOM   9204  C  CD    . GLN E 2 249 ? 222.478 218.763 250.717 1.00 45.82  ? 318 GLN F CD    1 
ATOM   9205  O  OE1   . GLN E 2 249 ? 223.509 219.012 250.089 1.00 46.22  ? 318 GLN F OE1   1 
ATOM   9206  N  NE2   . GLN E 2 249 ? 221.929 217.556 250.743 1.00 46.79  ? 318 GLN F NE2   1 
ATOM   9207  N  N     . PRO E 2 250 ? 218.889 223.844 251.017 1.00 45.74  ? 319 PRO F N     1 
ATOM   9208  C  CA    . PRO E 2 250 ? 218.448 225.037 250.301 1.00 45.99  ? 319 PRO F CA    1 
ATOM   9209  C  C     . PRO E 2 250 ? 219.627 225.908 249.881 1.00 45.36  ? 319 PRO F C     1 
ATOM   9210  O  O     . PRO E 2 250 ? 220.612 226.030 250.607 1.00 44.57  ? 319 PRO F O     1 
ATOM   9211  C  CB    . PRO E 2 250 ? 217.533 225.766 251.291 1.00 47.56  ? 319 PRO F CB    1 
ATOM   9212  C  CG    . PRO E 2 250 ? 217.235 224.746 252.368 1.00 47.20  ? 319 PRO F CG    1 
ATOM   9213  C  CD    . PRO E 2 250 ? 218.430 223.815 252.414 1.00 46.84  ? 319 PRO F CD    1 
ATOM   9214  N  N     . GLY E 2 251 ? 219.509 226.497 248.687 1.00 45.05  ? 320 GLY F N     1 
ATOM   9215  C  CA    . GLY E 2 251 ? 220.460 227.487 248.213 1.00 45.44  ? 320 GLY F CA    1 
ATOM   9216  C  C     . GLY E 2 251 ? 221.678 226.881 247.519 1.00 43.02  ? 320 GLY F C     1 
ATOM   9217  O  O     . GLY E 2 251 ? 222.503 227.623 246.994 1.00 45.71  ? 320 GLY F O     1 
ATOM   9218  N  N     . THR E 2 252 ? 221.808 225.549 247.515 1.00 43.53  ? 321 THR F N     1 
ATOM   9219  C  CA    . THR E 2 252 ? 222.943 224.913 246.860 1.00 43.90  ? 321 THR F CA    1 
ATOM   9220  C  C     . THR E 2 252 ? 222.903 225.198 245.358 1.00 41.08  ? 321 THR F C     1 
ATOM   9221  O  O     . THR E 2 252 ? 223.914 225.527 244.748 1.00 41.16  ? 321 THR F O     1 
ATOM   9222  C  CB    . THR E 2 252 ? 222.952 223.409 247.130 1.00 45.03  ? 321 THR F CB    1 
ATOM   9223  O  OG1   . THR E 2 252 ? 223.091 223.210 248.536 1.00 48.70  ? 321 THR F OG1   1 
ATOM   9224  C  CG2   . THR E 2 252 ? 224.111 222.730 246.421 1.00 44.50  ? 321 THR F CG2   1 
ATOM   9225  N  N     . SER E 2 253 ? 221.723 225.035 244.764 1.00 40.85  ? 322 SER F N     1 
ATOM   9226  C  CA    . SER E 2 253 ? 221.527 225.272 243.344 1.00 40.30  ? 322 SER F CA    1 
ATOM   9227  C  C     . SER E 2 253 ? 221.750 226.750 243.018 1.00 39.30  ? 322 SER F C     1 
ATOM   9228  O  O     . SER E 2 253 ? 222.402 227.082 242.035 1.00 36.65  ? 322 SER F O     1 
ATOM   9229  C  CB    . SER E 2 253 ? 220.149 224.800 242.947 1.00 42.07  ? 322 SER F CB    1 
ATOM   9230  O  OG    . SER E 2 253 ? 220.048 224.555 241.560 1.00 42.74  ? 322 SER F OG    1 
ATOM   9231  N  N     . LEU E 2 254 ? 221.213 227.642 243.858 1.00 37.04  ? 323 LEU F N     1 
ATOM   9232  C  CA    . LEU E 2 254 ? 221.374 229.077 243.668 1.00 36.32  ? 323 LEU F CA    1 
ATOM   9233  C  C     . LEU E 2 254 ? 222.841 229.491 243.799 1.00 35.87  ? 323 LEU F C     1 
ATOM   9234  O  O     . LEU E 2 254 ? 223.298 230.379 243.086 1.00 35.98  ? 323 LEU F O     1 
ATOM   9235  C  CB    . LEU E 2 254 ? 220.501 229.825 244.674 1.00 37.27  ? 323 LEU F CB    1 
ATOM   9236  C  CG    . LEU E 2 254 ? 220.438 231.351 244.545 1.00 38.83  ? 323 LEU F CG    1 
ATOM   9237  C  CD1   . LEU E 2 254 ? 219.747 231.773 243.261 1.00 39.33  ? 323 LEU F CD1   1 
ATOM   9238  C  CD2   . LEU E 2 254 ? 219.722 231.929 245.747 1.00 39.41  ? 323 LEU F CD2   1 
ATOM   9239  N  N     . ALA E 2 255 ? 223.583 228.847 244.701 1.00 34.80  ? 324 ALA F N     1 
ATOM   9240  C  CA    . ALA E 2 255 ? 224.984 229.182 244.910 1.00 33.92  ? 324 ALA F CA    1 
ATOM   9241  C  C     . ALA E 2 255 ? 225.812 228.873 243.665 1.00 34.63  ? 324 ALA F C     1 
ATOM   9242  O  O     . ALA E 2 255 ? 226.718 229.629 243.324 1.00 35.94  ? 324 ALA F O     1 
ATOM   9243  C  CB    . ALA E 2 255 ? 225.524 228.452 246.118 1.00 34.98  ? 324 ALA F CB    1 
ATOM   9244  N  N     . LYS E 2 256 ? 225.505 227.766 242.983 1.00 36.19  ? 325 LYS F N     1 
ATOM   9245  C  CA    . LYS E 2 256 ? 226.209 227.412 241.758 1.00 35.97  ? 325 LYS F CA    1 
ATOM   9246  C  C     . LYS E 2 256 ? 225.990 228.474 240.683 1.00 36.95  ? 325 LYS F C     1 
ATOM   9247  O  O     . LYS E 2 256 ? 226.907 228.804 239.937 1.00 39.20  ? 325 LYS F O     1 
ATOM   9248  C  CB    . LYS E 2 256 ? 225.768 226.039 241.244 1.00 37.49  ? 325 LYS F CB    1 
ATOM   9249  C  CG    . LYS E 2 256 ? 226.306 224.879 242.047 1.00 39.59  ? 325 LYS F CG    1 
ATOM   9250  C  CD    . LYS E 2 256 ? 225.925 223.527 241.459 1.00 42.04  ? 325 LYS F CD    1 
ATOM   9251  C  CE    . LYS E 2 256 ? 226.602 222.371 242.130 1.00 43.05  ? 325 LYS F CE    1 
ATOM   9252  N  NZ    . LYS E 2 256 ? 228.048 222.566 242.266 1.00 44.55  ? 325 LYS F NZ    1 
ATOM   9253  N  N     . ALA E 2 257 ? 224.764 229.002 240.600 1.00 38.35  ? 326 ALA F N     1 
ATOM   9254  C  CA    . ALA E 2 257 ? 224.431 230.020 239.618 1.00 39.87  ? 326 ALA F CA    1 
ATOM   9255  C  C     . ALA E 2 257 ? 224.954 231.396 240.021 1.00 44.19  ? 326 ALA F C     1 
ATOM   9256  O  O     . ALA E 2 257 ? 224.851 232.327 239.235 1.00 47.67  ? 326 ALA F O     1 
ATOM   9257  C  CB    . ALA E 2 257 ? 222.938 230.072 239.405 1.00 38.32  ? 326 ALA F CB    1 
ATOM   9258  N  N     . LYS E 2 258 ? 225.478 231.552 241.240 1.00 50.35  ? 327 LYS F N     1 
ATOM   9259  C  CA    . LYS E 2 258 ? 226.083 232.811 241.658 1.00 52.06  ? 327 LYS F CA    1 
ATOM   9260  C  C     . LYS E 2 258 ? 227.608 232.754 241.600 1.00 51.44  ? 327 LYS F C     1 
ATOM   9261  O  O     . LYS E 2 258 ? 228.244 233.788 241.417 1.00 56.18  ? 327 LYS F O     1 
ATOM   9262  C  CB    . LYS E 2 258 ? 225.633 233.189 243.068 1.00 55.94  ? 327 LYS F CB    1 
ATOM   9263  C  CG    . LYS E 2 258 ? 224.169 233.581 243.156 1.00 62.33  ? 327 LYS F CG    1 
ATOM   9264  C  CD    . LYS E 2 258 ? 223.755 234.060 244.544 1.00 68.58  ? 327 LYS F CD    1 
ATOM   9265  C  CE    . LYS E 2 258 ? 223.769 232.948 245.565 1.00 73.45  ? 327 LYS F CE    1 
ATOM   9266  N  NZ    . LYS E 2 258 ? 223.327 233.390 246.891 1.00 74.62  ? 327 LYS F NZ    1 
ATOM   9267  N  N     . ARG E 2 259 ? 228.195 231.563 241.761 1.00 55.45  ? 328 ARG F N     1 
ATOM   9268  C  CA    . ARG E 2 259 ? 229.635 231.406 241.608 1.00 59.60  ? 328 ARG F CA    1 
ATOM   9269  C  C     . ARG E 2 259 ? 230.048 231.804 240.192 1.00 57.83  ? 328 ARG F C     1 
ATOM   9270  O  O     . ARG E 2 259 ? 231.049 232.490 239.999 1.00 60.99  ? 328 ARG F O     1 
ATOM   9271  C  CB    . ARG E 2 259 ? 230.044 229.964 241.916 1.00 64.25  ? 328 ARG F CB    1 
ATOM   9272  C  CG    . ARG E 2 259 ? 231.546 229.727 241.889 1.00 73.09  ? 328 ARG F CG    1 
ATOM   9273  C  CD    . ARG E 2 259 ? 231.891 228.296 242.249 1.00 78.35  ? 328 ARG F CD    1 
ATOM   9274  N  NE    . ARG E 2 259 ? 231.408 227.956 243.592 1.00 84.08  ? 328 ARG F NE    1 
ATOM   9275  C  CZ    . ARG E 2 259 ? 230.434 227.096 243.877 1.00 89.54  ? 328 ARG F CZ    1 
ATOM   9276  N  NH1   . ARG E 2 259 ? 229.801 226.448 242.914 1.00 89.97  ? 328 ARG F NH1   1 
ATOM   9277  N  NH2   . ARG E 2 259 ? 230.088 226.892 245.135 1.00 91.92  ? 328 ARG F NH2   1 
ATOM   9278  N  N     . LEU E 2 260 ? 229.289 231.326 239.203 1.00 56.71  ? 329 LEU F N     1 
ATOM   9279  C  CA    . LEU E 2 260 ? 229.382 231.813 237.837 1.00 58.14  ? 329 LEU F CA    1 
ATOM   9280  C  C     . LEU E 2 260 ? 228.141 232.647 237.556 1.00 56.56  ? 329 LEU F C     1 
ATOM   9281  O  O     . LEU E 2 260 ? 227.030 232.154 237.714 1.00 65.41  ? 329 LEU F O     1 
ATOM   9282  C  CB    . LEU E 2 260 ? 229.500 230.655 236.849 1.00 63.58  ? 329 LEU F CB    1 
ATOM   9283  C  CG    . LEU E 2 260 ? 230.856 229.938 236.813 1.00 70.61  ? 329 LEU F CG    1 
ATOM   9284  C  CD1   . LEU E 2 260 ? 230.992 228.946 237.953 1.00 74.58  ? 329 LEU F CD1   1 
ATOM   9285  C  CD2   . LEU E 2 260 ? 231.089 229.246 235.489 1.00 73.29  ? 329 LEU F CD2   1 
ATOM   9286  N  N     . ASN E 2 261 ? 228.334 233.894 237.133 1.00 51.27  ? 330 ASN F N     1 
ATOM   9287  C  CA    . ASN E 2 261 ? 227.285 234.900 237.178 1.00 51.06  ? 330 ASN F CA    1 
ATOM   9288  C  C     . ASN E 2 261 ? 226.192 234.572 236.162 1.00 43.72  ? 330 ASN F C     1 
ATOM   9289  O  O     . ASN E 2 261 ? 226.173 235.109 235.056 1.00 45.41  ? 330 ASN F O     1 
ATOM   9290  C  CB    . ASN E 2 261 ? 227.864 236.293 236.945 1.00 57.58  ? 330 ASN F CB    1 
ATOM   9291  C  CG    . ASN E 2 261 ? 228.938 236.639 237.949 1.00 63.64  ? 330 ASN F CG    1 
ATOM   9292  O  OD1   . ASN E 2 261 ? 230.127 236.662 237.607 1.00 66.16  ? 330 ASN F OD1   1 
ATOM   9293  N  ND2   . ASN E 2 261 ? 228.546 236.893 239.190 1.00 66.73  ? 330 ASN F ND2   1 
ATOM   9294  N  N     . LEU E 2 262 ? 225.291 233.668 236.558 1.00 36.46  ? 331 LEU F N     1 
ATOM   9295  C  CA    . LEU E 2 262 ? 224.213 233.196 235.704 1.00 31.96  ? 331 LEU F CA    1 
ATOM   9296  C  C     . LEU E 2 262 ? 222.890 233.735 236.234 1.00 27.58  ? 331 LEU F C     1 
ATOM   9297  O  O     . LEU E 2 262 ? 222.679 233.810 237.441 1.00 29.14  ? 331 LEU F O     1 
ATOM   9298  C  CB    . LEU E 2 262 ? 224.186 231.669 235.659 1.00 31.14  ? 331 LEU F CB    1 
ATOM   9299  C  CG    . LEU E 2 262 ? 225.413 230.967 235.074 1.00 32.59  ? 331 LEU F CG    1 
ATOM   9300  C  CD1   . LEU E 2 262 ? 225.279 229.456 235.241 1.00 33.20  ? 331 LEU F CD1   1 
ATOM   9301  C  CD2   . LEU E 2 262 ? 225.620 231.337 233.618 1.00 33.32  ? 331 LEU F CD2   1 
ATOM   9302  N  N     . ALA E 2 263 ? 221.989 234.078 235.311 1.00 25.32  ? 332 ALA F N     1 
ATOM   9303  C  CA    . ALA E 2 263 ? 220.642 234.469 235.679 1.00 24.88  ? 332 ALA F CA    1 
ATOM   9304  C  C     . ALA E 2 263 ? 219.888 233.272 236.256 1.00 23.97  ? 332 ALA F C     1 
ATOM   9305  O  O     . ALA E 2 263 ? 220.075 232.135 235.827 1.00 25.06  ? 332 ALA F O     1 
ATOM   9306  C  CB    . ALA E 2 263 ? 219.936 235.046 234.477 1.00 24.67  ? 332 ALA F CB    1 
ATOM   9307  N  N     . THR E 2 264 ? 219.012 233.554 237.222 1.00 22.95  ? 333 THR F N     1 
ATOM   9308  C  CA    . THR E 2 264 ? 218.204 232.535 237.872 1.00 22.52  ? 333 THR F CA    1 
ATOM   9309  C  C     . THR E 2 264 ? 216.731 232.904 237.758 1.00 22.20  ? 333 THR F C     1 
ATOM   9310  O  O     . THR E 2 264 ? 216.363 234.071 237.736 1.00 22.88  ? 333 THR F O     1 
ATOM   9311  C  CB    . THR E 2 264 ? 218.597 232.351 239.338 1.00 23.44  ? 333 THR F CB    1 
ATOM   9312  O  OG1   . THR E 2 264 ? 218.137 233.479 240.081 1.00 25.23  ? 333 THR F OG1   1 
ATOM   9313  C  CG2   . THR E 2 264 ? 220.093 232.177 239.498 1.00 24.23  ? 333 THR F CG2   1 
ATOM   9314  N  N     . GLU E 2 265 ? 215.886 231.873 237.720 1.00 21.58  ? 334 GLU F N     1 
ATOM   9315  C  CA    . GLU E 2 265 ? 214.447 232.049 237.724 1.00 22.05  ? 334 GLU F CA    1 
ATOM   9316  C  C     . GLU E 2 265 ? 213.820 230.922 238.532 1.00 21.02  ? 334 GLU F C     1 
ATOM   9317  O  O     . GLU E 2 265 ? 214.389 229.842 238.658 1.00 20.60  ? 334 GLU F O     1 
ATOM   9318  C  CB    . GLU E 2 265 ? 213.865 232.081 236.313 1.00 25.50  ? 334 GLU F CB    1 
ATOM   9319  C  CG    . GLU E 2 265 ? 213.907 233.455 235.656 1.00 29.37  ? 334 GLU F CG    1 
ATOM   9320  C  CD    . GLU E 2 265 ? 213.355 233.460 234.244 1.00 34.66  ? 334 GLU F CD    1 
ATOM   9321  O  OE1   . GLU E 2 265 ? 213.076 232.366 233.701 1.00 33.86  ? 334 GLU F OE1   1 
ATOM   9322  O  OE2   . GLU E 2 265 ? 213.197 234.570 233.691 1.00 36.51  ? 334 GLU F OE2   1 
ATOM   9323  N  N     . CYS E 2 266 ? 212.633 231.204 239.081 1.00 20.52  ? 335 CYS F N     1 
ATOM   9324  C  CA    . CYS E 2 266 ? 211.845 230.216 239.789 1.00 20.81  ? 335 CYS F CA    1 
ATOM   9325  C  C     . CYS E 2 266 ? 210.464 230.135 239.157 1.00 19.87  ? 335 CYS F C     1 
ATOM   9326  O  O     . CYS E 2 266 ? 209.972 231.100 238.582 1.00 21.57  ? 335 CYS F O     1 
ATOM   9327  C  CB    . CYS E 2 266 ? 211.762 230.526 241.281 1.00 22.78  ? 335 CYS F CB    1 
ATOM   9328  S  SG    . CYS E 2 266 ? 210.838 232.032 241.673 1.00 23.82  ? 335 CYS F SG    1 
ATOM   9329  N  N     . LEU E 2 267 ? 209.841 228.966 239.283 1.00 19.88  ? 336 LEU F N     1 
ATOM   9330  C  CA    . LEU E 2 267 ? 208.485 228.789 238.802 1.00 20.67  ? 336 LEU F CA    1 
ATOM   9331  C  C     . LEU E 2 267 ? 207.539 229.678 239.603 1.00 21.51  ? 336 LEU F C     1 
ATOM   9332  O  O     . LEU E 2 267 ? 207.672 229.803 240.818 1.00 20.18  ? 336 LEU F O     1 
ATOM   9333  C  CB    . LEU E 2 267 ? 208.055 227.327 238.908 1.00 21.03  ? 336 LEU F CB    1 
ATOM   9334  C  CG    . LEU E 2 267 ? 208.723 226.356 237.927 1.00 21.01  ? 336 LEU F CG    1 
ATOM   9335  C  CD1   . LEU E 2 267 ? 208.088 224.995 238.087 1.00 21.27  ? 336 LEU F CD1   1 
ATOM   9336  C  CD2   . LEU E 2 267 ? 208.625 226.844 236.498 1.00 19.42  ? 336 LEU F CD2   1 
ATOM   9337  N  N     . PRO E 2 268 ? 206.524 230.278 238.947 1.00 22.36  ? 337 PRO F N     1 
ATOM   9338  C  CA    . PRO E 2 268 ? 205.508 231.072 239.644 1.00 22.55  ? 337 PRO F CA    1 
ATOM   9339  C  C     . PRO E 2 268 ? 204.462 230.238 240.372 1.00 22.49  ? 337 PRO F C     1 
ATOM   9340  O  O     . PRO E 2 268 ? 203.269 230.368 240.124 1.00 24.19  ? 337 PRO F O     1 
ATOM   9341  C  CB    . PRO E 2 268 ? 204.904 231.889 238.494 1.00 22.67  ? 337 PRO F CB    1 
ATOM   9342  C  CG    . PRO E 2 268 ? 205.008 230.973 237.307 1.00 23.22  ? 337 PRO F CG    1 
ATOM   9343  C  CD    . PRO E 2 268 ? 206.328 230.252 237.491 1.00 22.98  ? 337 PRO F CD    1 
ATOM   9344  N  N     . LEU E 2 269 ? 204.918 229.389 241.294 1.00 24.27  ? 338 LEU F N     1 
ATOM   9345  C  CA    . LEU E 2 269 ? 204.022 228.488 242.002 1.00 25.74  ? 338 LEU F CA    1 
ATOM   9346  C  C     . LEU E 2 269 ? 203.066 229.282 242.894 1.00 27.85  ? 338 LEU F C     1 
ATOM   9347  O  O     . LEU E 2 269 ? 201.874 228.985 242.954 1.00 27.87  ? 338 LEU F O     1 
ATOM   9348  C  CB    . LEU E 2 269 ? 204.821 227.479 242.824 1.00 25.67  ? 338 LEU F CB    1 
ATOM   9349  C  CG    . LEU E 2 269 ? 205.818 226.619 242.046 1.00 24.90  ? 338 LEU F CG    1 
ATOM   9350  C  CD1   . LEU E 2 269 ? 206.460 225.602 242.966 1.00 24.51  ? 338 LEU F CD1   1 
ATOM   9351  C  CD2   . LEU E 2 269 ? 205.156 225.945 240.871 1.00 24.39  ? 338 LEU F CD2   1 
ATOM   9352  N  N     . ASP E 2 270 ? 203.589 230.290 243.596 1.00 30.69  ? 339 ASP F N     1 
ATOM   9353  C  CA    . ASP E 2 270 ? 202.760 231.094 244.480 1.00 34.78  ? 339 ASP F CA    1 
ATOM   9354  C  C     . ASP E 2 270 ? 201.808 231.983 243.686 1.00 36.53  ? 339 ASP F C     1 
ATOM   9355  O  O     . ASP E 2 270 ? 200.695 232.256 244.134 1.00 40.37  ? 339 ASP F O     1 
ATOM   9356  C  CB    . ASP E 2 270 ? 203.618 231.897 245.435 1.00 36.09  ? 339 ASP F CB    1 
ATOM   9357  C  CG    . ASP E 2 270 ? 204.401 231.031 246.410 1.00 39.04  ? 339 ASP F CG    1 
ATOM   9358  O  OD1   . ASP E 2 270 ? 203.777 230.142 247.039 1.00 41.65  ? 339 ASP F OD1   1 
ATOM   9359  O  OD2   . ASP E 2 270 ? 205.626 231.237 246.526 1.00 41.21  ? 339 ASP F OD2   1 
ATOM   9360  N  N     . LYS E 2 271 ? 202.250 232.442 242.515 1.00 36.74  ? 340 LYS F N     1 
ATOM   9361  C  CA    . LYS E 2 271 ? 201.445 233.342 241.707 1.00 35.30  ? 340 LYS F CA    1 
ATOM   9362  C  C     . LYS E 2 271 ? 200.181 232.651 241.204 1.00 35.42  ? 340 LYS F C     1 
ATOM   9363  O  O     . LYS E 2 271 ? 199.121 233.271 241.148 1.00 41.78  ? 340 LYS F O     1 
ATOM   9364  C  CB    . LYS E 2 271 ? 202.258 233.881 240.528 1.00 37.87  ? 340 LYS F CB    1 
ATOM   9365  C  CG    . LYS E 2 271 ? 201.466 234.757 239.577 1.00 38.25  ? 340 LYS F CG    1 
ATOM   9366  C  CD    . LYS E 2 271 ? 202.331 235.418 238.517 1.00 42.12  ? 340 LYS F CD    1 
ATOM   9367  C  CE    . LYS E 2 271 ? 201.582 236.454 237.743 1.00 44.70  ? 340 LYS F CE    1 
ATOM   9368  N  NZ    . LYS E 2 271 ? 200.474 235.881 236.980 1.00 46.75  ? 340 LYS F NZ    1 
ATOM   9369  N  N     . TYR E 2 272 ? 200.277 231.367 240.840 1.00 33.17  ? 341 TYR F N     1 
ATOM   9370  C  CA    . TYR E 2 272 ? 199.166 230.685 240.190 1.00 31.26  ? 341 TYR F CA    1 
ATOM   9371  C  C     . TYR E 2 272 ? 198.488 229.650 241.085 1.00 31.09  ? 341 TYR F C     1 
ATOM   9372  O  O     . TYR E 2 272 ? 197.315 229.358 240.868 1.00 33.60  ? 341 TYR F O     1 
ATOM   9373  C  CB    . TYR E 2 272 ? 199.631 230.008 238.901 1.00 31.57  ? 341 TYR F CB    1 
ATOM   9374  C  CG    . TYR E 2 272 ? 199.955 230.995 237.793 1.00 32.91  ? 341 TYR F CG    1 
ATOM   9375  C  CD1   . TYR E 2 272 ? 198.954 231.503 236.977 1.00 34.77  ? 341 TYR F CD1   1 
ATOM   9376  C  CD2   . TYR E 2 272 ? 201.254 231.423 237.567 1.00 33.38  ? 341 TYR F CD2   1 
ATOM   9377  C  CE1   . TYR E 2 272 ? 199.236 232.404 235.966 1.00 35.46  ? 341 TYR F CE1   1 
ATOM   9378  C  CE2   . TYR E 2 272 ? 201.550 232.329 236.560 1.00 35.16  ? 341 TYR F CE2   1 
ATOM   9379  C  CZ    . TYR E 2 272 ? 200.539 232.817 235.755 1.00 36.31  ? 341 TYR F CZ    1 
ATOM   9380  O  OH    . TYR E 2 272 ? 200.834 233.709 234.764 1.00 38.30  ? 341 TYR F OH    1 
ATOM   9381  N  N     . LEU E 2 273 ? 199.200 229.089 242.070 1.00 31.21  ? 342 LEU F N     1 
ATOM   9382  C  CA    . LEU E 2 273 ? 198.666 227.981 242.848 1.00 31.76  ? 342 LEU F CA    1 
ATOM   9383  C  C     . LEU E 2 273 ? 198.508 228.397 244.304 1.00 32.03  ? 342 LEU F C     1 
ATOM   9384  O  O     . LEU E 2 273 ? 199.362 229.087 244.856 1.00 32.04  ? 342 LEU F O     1 
ATOM   9385  C  CB    . LEU E 2 273 ? 199.563 226.747 242.750 1.00 32.67  ? 342 LEU F CB    1 
ATOM   9386  C  CG    . LEU E 2 273 ? 199.751 226.143 241.356 1.00 32.28  ? 342 LEU F CG    1 
ATOM   9387  C  CD1   . LEU E 2 273 ? 200.920 225.180 241.365 1.00 32.78  ? 342 LEU F CD1   1 
ATOM   9388  C  CD2   . LEU E 2 273 ? 198.484 225.452 240.903 1.00 33.02  ? 342 LEU F CD2   1 
ATOM   9389  N  N     . GLN E 2 274 ? 197.410 227.939 244.914 1.00 33.51  ? 343 GLN F N     1 
ATOM   9390  C  CA    . GLN E 2 274 ? 197.181 228.104 246.338 1.00 34.44  ? 343 GLN F CA    1 
ATOM   9391  C  C     . GLN E 2 274 ? 197.913 226.981 247.064 1.00 31.43  ? 343 GLN F C     1 
ATOM   9392  O  O     . GLN E 2 274 ? 197.352 225.919 247.316 1.00 32.08  ? 343 GLN F O     1 
ATOM   9393  C  CB    . GLN E 2 274 ? 195.682 228.097 246.643 1.00 36.71  ? 343 GLN F CB    1 
ATOM   9394  C  CG    . GLN E 2 274 ? 195.341 228.381 248.101 1.00 41.18  ? 343 GLN F CG    1 
ATOM   9395  C  CD    . GLN E 2 274 ? 195.844 229.728 248.567 1.00 46.64  ? 343 GLN F CD    1 
ATOM   9396  O  OE1   . GLN E 2 274 ? 196.662 229.827 249.490 1.00 51.78  ? 343 GLN F OE1   1 
ATOM   9397  N  NE2   . GLN E 2 274 ? 195.373 230.780 247.912 1.00 50.55  ? 343 GLN F NE2   1 
ATOM   9398  N  N     . TRP E 2 275 ? 199.179 227.227 247.384 1.00 31.00  ? 344 TRP F N     1 
ATOM   9399  C  CA    . TRP E 2 275 ? 200.019 226.201 247.973 1.00 32.40  ? 344 TRP F CA    1 
ATOM   9400  C  C     . TRP E 2 275 ? 199.525 225.840 249.370 1.00 37.32  ? 344 TRP F C     1 
ATOM   9401  O  O     . TRP E 2 275 ? 199.197 226.727 250.161 1.00 38.27  ? 344 TRP F O     1 
ATOM   9402  C  CB    . TRP E 2 275 ? 201.468 226.694 248.023 1.00 31.90  ? 344 TRP F CB    1 
ATOM   9403  C  CG    . TRP E 2 275 ? 202.474 225.581 248.062 1.00 29.87  ? 344 TRP F CG    1 
ATOM   9404  C  CD1   . TRP E 2 275 ? 203.083 225.063 249.162 1.00 29.15  ? 344 TRP F CD1   1 
ATOM   9405  C  CD2   . TRP E 2 275 ? 202.978 224.848 246.930 1.00 27.64  ? 344 TRP F CD2   1 
ATOM   9406  N  NE1   . TRP E 2 275 ? 203.945 224.068 248.795 1.00 28.76  ? 344 TRP F NE1   1 
ATOM   9407  C  CE2   . TRP E 2 275 ? 203.900 223.908 247.437 1.00 28.20  ? 344 TRP F CE2   1 
ATOM   9408  C  CE3   . TRP E 2 275 ? 202.751 224.897 245.553 1.00 27.72  ? 344 TRP F CE3   1 
ATOM   9409  C  CZ2   . TRP E 2 275 ? 204.593 223.024 246.614 1.00 26.49  ? 344 TRP F CZ2   1 
ATOM   9410  C  CZ3   . TRP E 2 275 ? 203.436 224.020 244.741 1.00 26.46  ? 344 TRP F CZ3   1 
ATOM   9411  C  CH2   . TRP E 2 275 ? 204.343 223.099 245.265 1.00 25.39  ? 344 TRP F CH2   1 
ATOM   9412  N  N     . GLU E 2 276 ? 199.506 224.536 249.678 1.00 40.33  ? 345 GLU F N     1 
ATOM   9413  C  CA    . GLU E 2 276 ? 199.119 224.072 251.004 1.00 44.70  ? 345 GLU F CA    1 
ATOM   9414  C  C     . GLU E 2 276 ? 200.283 223.402 251.737 1.00 41.28  ? 345 GLU F C     1 
ATOM   9415  O  O     . GLU E 2 276 ? 200.640 223.827 252.833 1.00 41.78  ? 345 GLU F O     1 
ATOM   9416  C  CB    . GLU E 2 276 ? 197.872 223.188 250.963 1.00 53.92  ? 345 GLU F CB    1 
ATOM   9417  C  CG    . GLU E 2 276 ? 198.014 221.882 250.182 1.00 62.61  ? 345 GLU F CG    1 
ATOM   9418  C  CD    . GLU E 2 276 ? 196.757 221.026 250.200 1.00 70.16  ? 345 GLU F CD    1 
ATOM   9419  O  OE1   . GLU E 2 276 ? 195.773 221.430 250.865 1.00 72.70  ? 345 GLU F OE1   1 
ATOM   9420  O  OE2   . GLU E 2 276 ? 196.748 219.953 249.562 1.00 70.18  ? 345 GLU F OE2   1 
ATOM   9421  N  N     . ILE E 2 277 ? 200.855 222.338 251.158 1.00 42.21  ? 346 ILE F N     1 
ATOM   9422  C  CA    . ILE E 2 277 ? 201.878 221.553 251.837 1.00 42.45  ? 346 ILE F CA    1 
ATOM   9423  C  C     . ILE E 2 277 ? 202.990 221.207 250.855 1.00 39.16  ? 346 ILE F C     1 
ATOM   9424  O  O     . ILE E 2 277 ? 202.866 221.397 249.642 1.00 42.84  ? 346 ILE F O     1 
ATOM   9425  C  CB    . ILE E 2 277 ? 201.305 220.263 252.456 1.00 46.56  ? 346 ILE F CB    1 
ATOM   9426  C  CG1   . ILE E 2 277 ? 200.986 219.236 251.371 1.00 49.12  ? 346 ILE F CG1   1 
ATOM   9427  C  CG2   . ILE E 2 277 ? 200.103 220.558 253.354 1.00 47.80  ? 346 ILE F CG2   1 
ATOM   9428  C  CD1   . ILE E 2 277 ? 200.404 217.931 251.881 1.00 50.84  ? 346 ILE F CD1   1 
ATOM   9429  N  N     . GLY E 2 278 ? 204.072 220.680 251.419 1.00 36.71  ? 347 GLY F N     1 
ATOM   9430  C  CA    . GLY E 2 278 ? 205.104 220.027 250.639 1.00 36.65  ? 347 GLY F CA    1 
ATOM   9431  C  C     . GLY E 2 278 ? 206.168 220.996 250.137 1.00 33.42  ? 347 GLY F C     1 
ATOM   9432  O  O     . GLY E 2 278 ? 206.003 222.212 250.152 1.00 31.39  ? 347 GLY F O     1 
ATOM   9433  N  N     . ASN E 2 279 ? 207.272 220.405 249.689 1.00 31.44  ? 348 ASN F N     1 
ATOM   9434  C  CA    . ASN E 2 279 ? 208.405 221.150 249.175 1.00 29.60  ? 348 ASN F CA    1 
ATOM   9435  C  C     . ASN E 2 279 ? 208.013 221.829 247.865 1.00 26.74  ? 348 ASN F C     1 
ATOM   9436  O  O     . ASN E 2 279 ? 207.314 221.248 247.039 1.00 26.48  ? 348 ASN F O     1 
ATOM   9437  C  CB    . ASN E 2 279 ? 209.605 220.228 248.996 1.00 30.80  ? 348 ASN F CB    1 
ATOM   9438  C  CG    . ASN E 2 279 ? 210.869 220.974 248.645 1.00 34.05  ? 348 ASN F CG    1 
ATOM   9439  O  OD1   . ASN E 2 279 ? 210.847 222.191 248.434 1.00 35.65  ? 348 ASN F OD1   1 
ATOM   9440  N  ND2   . ASN E 2 279 ? 211.981 220.259 248.567 1.00 36.47  ? 348 ASN F ND2   1 
ATOM   9441  N  N     . LYS E 2 280 ? 208.514 223.044 247.663 1.00 25.78  ? 349 LYS F N     1 
ATOM   9442  C  CA    . LYS E 2 280 ? 208.300 223.750 246.408 1.00 24.75  ? 349 LYS F CA    1 
ATOM   9443  C  C     . LYS E 2 280 ? 209.358 223.384 245.366 1.00 23.13  ? 349 LYS F C     1 
ATOM   9444  O  O     . LYS E 2 280 ? 209.280 223.872 244.247 1.00 22.06  ? 349 LYS F O     1 
ATOM   9445  C  CB    . LYS E 2 280 ? 208.281 225.263 246.628 1.00 26.14  ? 349 LYS F CB    1 
ATOM   9446  C  CG    . LYS E 2 280 ? 207.049 225.728 247.373 1.00 28.69  ? 349 LYS F CG    1 
ATOM   9447  C  CD    . LYS E 2 280 ? 206.983 227.229 247.589 1.00 30.38  ? 349 LYS F CD    1 
ATOM   9448  C  CE    . LYS E 2 280 ? 205.737 227.637 248.313 1.00 32.02  ? 349 LYS F CE    1 
ATOM   9449  N  NZ    . LYS E 2 280 ? 205.674 229.069 248.614 1.00 34.12  ? 349 LYS F NZ    1 
ATOM   9450  N  N     . ASN E 2 281 ? 210.323 222.528 245.727 1.00 23.37  ? 350 ASN F N     1 
ATOM   9451  C  CA    . ASN E 2 281 ? 211.284 221.991 244.779 1.00 24.74  ? 350 ASN F CA    1 
ATOM   9452  C  C     . ASN E 2 281 ? 210.678 220.754 244.117 1.00 23.23  ? 350 ASN F C     1 
ATOM   9453  O  O     . ASN E 2 281 ? 210.607 219.692 244.732 1.00 25.28  ? 350 ASN F O     1 
ATOM   9454  C  CB    . ASN E 2 281 ? 212.604 221.675 245.471 1.00 26.84  ? 350 ASN F CB    1 
ATOM   9455  C  CG    . ASN E 2 281 ? 213.272 222.905 246.033 1.00 32.22  ? 350 ASN F CG    1 
ATOM   9456  O  OD1   . ASN E 2 281 ? 213.882 223.680 245.287 1.00 34.50  ? 350 ASN F OD1   1 
ATOM   9457  N  ND2   . ASN E 2 281 ? 213.176 223.111 247.341 1.00 35.37  ? 350 ASN F ND2   1 
ATOM   9458  N  N     . LEU E 2 282 ? 210.258 220.893 242.861 1.00 19.77  ? 351 LEU F N     1 
ATOM   9459  C  CA    . LEU E 2 282 ? 209.615 219.810 242.138 1.00 18.98  ? 351 LEU F CA    1 
ATOM   9460  C  C     . LEU E 2 282 ? 210.653 218.831 241.595 1.00 18.19  ? 351 LEU F C     1 
ATOM   9461  O  O     . LEU E 2 282 ? 211.832 219.142 241.471 1.00 19.13  ? 351 LEU F O     1 
ATOM   9462  C  CB    . LEU E 2 282 ? 208.770 220.390 241.004 1.00 18.56  ? 351 LEU F CB    1 
ATOM   9463  C  CG    . LEU E 2 282 ? 207.827 221.528 241.398 1.00 18.60  ? 351 LEU F CG    1 
ATOM   9464  C  CD1   . LEU E 2 282 ? 207.011 221.964 240.216 1.00 19.10  ? 351 LEU F CD1   1 
ATOM   9465  C  CD2   . LEU E 2 282 ? 206.943 221.127 242.561 1.00 18.94  ? 351 LEU F CD2   1 
ATOM   9466  N  N     . THR E 2 283 ? 210.177 217.660 241.184 1.00 16.50  ? 352 THR F N     1 
ATOM   9467  C  CA    . THR E 2 283 ? 211.051 216.624 240.651 1.00 15.89  ? 352 THR F CA    1 
ATOM   9468  C  C     . THR E 2 283 ? 211.465 216.967 239.223 1.00 15.09  ? 352 THR F C     1 
ATOM   9469  O  O     . THR E 2 283 ? 210.871 217.827 238.576 1.00 15.30  ? 352 THR F O     1 
ATOM   9470  C  CB    . THR E 2 283 ? 210.366 215.257 240.719 1.00 15.39  ? 352 THR F CB    1 
ATOM   9471  O  OG1   . THR E 2 283 ? 209.385 215.189 239.688 1.00 14.76  ? 352 THR F OG1   1 
ATOM   9472  C  CG2   . THR E 2 283 ? 209.729 215.008 242.073 1.00 15.67  ? 352 THR F CG2   1 
ATOM   9473  N  N     . LEU E 2 284 ? 212.478 216.251 238.724 1.00 15.30  ? 353 LEU F N     1 
ATOM   9474  C  CA    . LEU E 2 284 ? 212.999 216.503 237.390 1.00 15.96  ? 353 LEU F CA    1 
ATOM   9475  C  C     . LEU E 2 284 ? 211.943 216.224 236.324 1.00 15.33  ? 353 LEU F C     1 
ATOM   9476  O  O     . LEU E 2 284 ? 211.798 216.986 235.374 1.00 15.61  ? 353 LEU F O     1 
ATOM   9477  C  CB    . LEU E 2 284 ? 214.252 215.669 237.135 1.00 16.99  ? 353 LEU F CB    1 
ATOM   9478  C  CG    . LEU E 2 284 ? 215.442 215.930 238.056 1.00 18.67  ? 353 LEU F CG    1 
ATOM   9479  C  CD1   . LEU E 2 284 ? 216.671 215.197 237.574 1.00 18.76  ? 353 LEU F CD1   1 
ATOM   9480  C  CD2   . LEU E 2 284 ? 215.736 217.405 238.145 1.00 19.95  ? 353 LEU F CD2   1 
ATOM   9481  N  N     . ASP E 2 285 ? 211.223 215.113 236.459 1.00 15.82  ? 354 ASP F N     1 
ATOM   9482  C  CA    . ASP E 2 285 ? 210.219 214.734 235.477 1.00 17.25  ? 354 ASP F CA    1 
ATOM   9483  C  C     . ASP E 2 285 ? 209.094 215.769 235.436 1.00 16.27  ? 354 ASP F C     1 
ATOM   9484  O  O     . ASP E 2 285 ? 208.568 216.075 234.370 1.00 16.66  ? 354 ASP F O     1 
ATOM   9485  C  CB    . ASP E 2 285 ? 209.672 213.350 235.774 1.00 19.26  ? 354 ASP F CB    1 
ATOM   9486  C  CG    . ASP E 2 285 ? 209.191 213.190 237.208 1.00 22.05  ? 354 ASP F CG    1 
ATOM   9487  O  OD1   . ASP E 2 285 ? 210.065 213.093 238.101 1.00 22.66  ? 354 ASP F OD1   1 
ATOM   9488  O  OD2   . ASP E 2 285 ? 207.954 213.203 237.417 1.00 22.35  ? 354 ASP F OD2   1 
ATOM   9489  N  N     . GLN E 2 286 ? 208.723 216.311 236.596 1.00 15.17  ? 355 GLN F N     1 
ATOM   9490  C  CA    . GLN E 2 286 ? 207.704 217.351 236.649 1.00 15.12  ? 355 GLN F CA    1 
ATOM   9491  C  C     . GLN E 2 286 ? 208.205 218.627 235.982 1.00 14.66  ? 355 GLN F C     1 
ATOM   9492  O  O     . GLN E 2 286 ? 207.451 219.296 235.285 1.00 15.08  ? 355 GLN F O     1 
ATOM   9493  C  CB    . GLN E 2 286 ? 207.289 217.613 238.096 1.00 14.78  ? 355 GLN F CB    1 
ATOM   9494  C  CG    . GLN E 2 286 ? 206.562 216.428 238.719 1.00 15.13  ? 355 GLN F CG    1 
ATOM   9495  C  CD    . GLN E 2 286 ? 206.587 216.434 240.229 1.00 15.43  ? 355 GLN F CD    1 
ATOM   9496  O  OE1   . GLN E 2 286 ? 207.034 217.394 240.864 1.00 16.30  ? 355 GLN F OE1   1 
ATOM   9497  N  NE2   . GLN E 2 286 ? 206.120 215.352 240.827 1.00 16.07  ? 355 GLN F NE2   1 
ATOM   9498  N  N     . MET E 2 287 ? 209.481 218.962 236.193 1.00 14.89  ? 356 MET F N     1 
ATOM   9499  C  CA    . MET E 2 287 ? 210.037 220.186 235.636 1.00 14.86  ? 356 MET F CA    1 
ATOM   9500  C  C     . MET E 2 287 ? 210.025 220.128 234.105 1.00 13.46  ? 356 MET F C     1 
ATOM   9501  O  O     . MET E 2 287 ? 209.617 221.088 233.455 1.00 13.25  ? 356 MET F O     1 
ATOM   9502  C  CB    . MET E 2 287 ? 211.457 220.424 236.146 1.00 15.81  ? 356 MET F CB    1 
ATOM   9503  C  CG    . MET E 2 287 ? 211.503 220.778 237.630 1.00 17.99  ? 356 MET F CG    1 
ATOM   9504  S  SD    . MET E 2 287 ? 210.750 222.378 237.997 1.00 19.26  ? 356 MET F SD    1 
ATOM   9505  C  CE    . MET E 2 287 ? 211.498 223.415 236.736 1.00 19.27  ? 356 MET F CE    1 
ATOM   9506  N  N     . ILE E 2 288 ? 210.490 219.022 233.521 1.00 12.89  ? 357 ILE F N     1 
ATOM   9507  C  CA    . ILE E 2 288 ? 210.592 218.956 232.072 1.00 13.14  ? 357 ILE F CA    1 
ATOM   9508  C  C     . ILE E 2 288 ? 209.207 218.975 231.431 1.00 13.18  ? 357 ILE F C     1 
ATOM   9509  O  O     . ILE E 2 288 ? 209.015 219.579 230.376 1.00 13.01  ? 357 ILE F O     1 
ATOM   9510  C  CB    . ILE E 2 288 ? 211.424 217.754 231.604 1.00 13.57  ? 357 ILE F CB    1 
ATOM   9511  C  CG1   . ILE E 2 288 ? 211.780 217.921 230.115 1.00 13.87  ? 357 ILE F CG1   1 
ATOM   9512  C  CG2   . ILE E 2 288 ? 210.708 216.438 231.896 1.00 13.10  ? 357 ILE F CG2   1 
ATOM   9513  C  CD1   . ILE E 2 288 ? 212.906 217.028 229.650 1.00 14.58  ? 357 ILE F CD1   1 
ATOM   9514  N  N     . ARG E 2 289 ? 208.232 218.342 232.080 1.00 13.84  ? 358 ARG F N     1 
ATOM   9515  C  CA    . ARG E 2 289 ? 206.868 218.355 231.571 1.00 14.78  ? 358 ARG F CA    1 
ATOM   9516  C  C     . ARG E 2 289 ? 206.274 219.759 231.628 1.00 13.73  ? 358 ARG F C     1 
ATOM   9517  O  O     . ARG E 2 289 ? 205.563 220.157 230.722 1.00 13.58  ? 358 ARG F O     1 
ATOM   9518  C  CB    . ARG E 2 289 ? 205.990 217.349 232.313 1.00 15.85  ? 358 ARG F CB    1 
ATOM   9519  C  CG    . ARG E 2 289 ? 206.099 215.942 231.743 1.00 17.96  ? 358 ARG F CG    1 
ATOM   9520  C  CD    . ARG E 2 289 ? 205.192 214.965 232.447 1.00 19.39  ? 358 ARG F CD    1 
ATOM   9521  N  NE    . ARG E 2 289 ? 205.800 214.512 233.696 1.00 22.50  ? 358 ARG F NE    1 
ATOM   9522  C  CZ    . ARG E 2 289 ? 205.172 213.809 234.629 1.00 25.66  ? 358 ARG F CZ    1 
ATOM   9523  N  NH1   . ARG E 2 289 ? 203.911 213.456 234.439 1.00 26.50  ? 358 ARG F NH1   1 
ATOM   9524  N  NH2   . ARG E 2 289 ? 205.820 213.478 235.738 1.00 25.69  ? 358 ARG F NH2   1 
ATOM   9525  N  N     . ILE E 2 290 ? 206.566 220.506 232.695 1.00 14.04  ? 359 ILE F N     1 
ATOM   9526  C  CA    . ILE E 2 290 ? 206.147 221.899 232.778 1.00 13.63  ? 359 ILE F CA    1 
ATOM   9527  C  C     . ILE E 2 290 ? 206.796 222.696 231.645 1.00 12.65  ? 359 ILE F C     1 
ATOM   9528  O  O     . ILE E 2 290 ? 206.133 223.459 230.955 1.00 13.04  ? 359 ILE F O     1 
ATOM   9529  C  CB    . ILE E 2 290 ? 206.483 222.491 234.158 1.00 13.88  ? 359 ILE F CB    1 
ATOM   9530  C  CG1   . ILE E 2 290 ? 205.603 221.895 235.232 1.00 14.48  ? 359 ILE F CG1   1 
ATOM   9531  C  CG2   . ILE E 2 290 ? 206.373 224.011 234.135 1.00 14.47  ? 359 ILE F CG2   1 
ATOM   9532  C  CD1   . ILE E 2 290 ? 206.140 222.060 236.636 1.00 14.47  ? 359 ILE F CD1   1 
ATOM   9533  N  N     . LEU E 2 291 ? 208.104 222.525 231.455 1.00 12.54  ? 360 LEU F N     1 
ATOM   9534  C  CA    . LEU E 2 291 ? 208.822 223.258 230.420 1.00 13.01  ? 360 LEU F CA    1 
ATOM   9535  C  C     . LEU E 2 291 ? 208.357 222.847 229.027 1.00 12.20  ? 360 LEU F C     1 
ATOM   9536  O  O     . LEU E 2 291 ? 208.216 223.697 228.154 1.00 12.09  ? 360 LEU F O     1 
ATOM   9537  C  CB    . LEU E 2 291 ? 210.325 223.061 230.572 1.00 13.28  ? 360 LEU F CB    1 
ATOM   9538  C  CG    . LEU E 2 291 ? 210.960 223.695 231.814 1.00 14.19  ? 360 LEU F CG    1 
ATOM   9539  C  CD1   . LEU E 2 291 ? 212.439 223.343 231.883 1.00 14.92  ? 360 LEU F CD1   1 
ATOM   9540  C  CD2   . LEU E 2 291 ? 210.761 225.189 231.811 1.00 14.35  ? 360 LEU F CD2   1 
ATOM   9541  N  N     . LEU E 2 292 ? 208.102 221.552 228.828 1.00 12.44  ? 361 LEU F N     1 
ATOM   9542  C  CA    . LEU E 2 292 ? 207.628 221.071 227.536 1.00 13.70  ? 361 LEU F CA    1 
ATOM   9543  C  C     . LEU E 2 292 ? 206.274 221.681 227.195 1.00 14.88  ? 361 LEU F C     1 
ATOM   9544  O  O     . LEU E 2 292 ? 206.029 222.044 226.052 1.00 16.24  ? 361 LEU F O     1 
ATOM   9545  C  CB    . LEU E 2 292 ? 207.559 219.547 227.513 1.00 12.86  ? 361 LEU F CB    1 
ATOM   9546  C  CG    . LEU E 2 292 ? 208.888 218.835 227.273 1.00 13.09  ? 361 LEU F CG    1 
ATOM   9547  C  CD1   . LEU E 2 292 ? 208.735 217.356 227.585 1.00 12.76  ? 361 LEU F CD1   1 
ATOM   9548  C  CD2   . LEU E 2 292 ? 209.374 219.064 225.836 1.00 12.78  ? 361 LEU F CD2   1 
ATOM   9549  N  N     . CYS E 2 293 ? 205.389 221.777 228.182 1.00 16.81  ? 362 CYS F N     1 
ATOM   9550  C  CA    . CYS E 2 293 ? 204.083 222.381 227.974 1.00 18.47  ? 362 CYS F CA    1 
ATOM   9551  C  C     . CYS E 2 293 ? 204.233 223.858 227.625 1.00 17.77  ? 362 CYS F C     1 
ATOM   9552  O  O     . CYS E 2 293 ? 203.576 224.346 226.712 1.00 18.75  ? 362 CYS F O     1 
ATOM   9553  C  CB    . CYS E 2 293 ? 203.205 222.182 229.202 1.00 21.00  ? 362 CYS F CB    1 
ATOM   9554  S  SG    . CYS E 2 293 ? 201.545 222.867 229.022 1.00 27.61  ? 362 CYS F SG    1 
ATOM   9555  N  N     . LEU E 2 294 ? 205.104 224.568 228.347 1.00 17.90  ? 363 LEU F N     1 
ATOM   9556  C  CA    . LEU E 2 294 ? 205.315 225.983 228.091 1.00 18.57  ? 363 LEU F CA    1 
ATOM   9557  C  C     . LEU E 2 294 ? 205.930 226.210 226.713 1.00 18.90  ? 363 LEU F C     1 
ATOM   9558  O  O     . LEU E 2 294 ? 205.557 227.148 226.016 1.00 17.86  ? 363 LEU F O     1 
ATOM   9559  C  CB    . LEU E 2 294 ? 206.208 226.585 229.167 1.00 19.76  ? 363 LEU F CB    1 
ATOM   9560  C  CG    . LEU E 2 294 ? 205.582 226.718 230.554 1.00 21.28  ? 363 LEU F CG    1 
ATOM   9561  C  CD1   . LEU E 2 294 ? 206.660 227.121 231.535 1.00 21.70  ? 363 LEU F CD1   1 
ATOM   9562  C  CD2   . LEU E 2 294 ? 204.458 227.726 230.531 1.00 21.42  ? 363 LEU F CD2   1 
ATOM   9563  N  N     . LYS E 2 295 ? 206.888 225.365 226.322 1.00 18.67  ? 364 LYS F N     1 
ATOM   9564  C  CA    . LYS E 2 295 ? 207.521 225.517 225.024 1.00 19.58  ? 364 LYS F CA    1 
ATOM   9565  C  C     . LYS E 2 295 ? 206.510 225.343 223.890 1.00 19.74  ? 364 LYS F C     1 
ATOM   9566  O  O     . LYS E 2 295 ? 206.653 225.965 222.840 1.00 20.19  ? 364 LYS F O     1 
ATOM   9567  C  CB    . LYS E 2 295 ? 208.662 224.511 224.869 1.00 20.26  ? 364 LYS F CB    1 
ATOM   9568  C  CG    . LYS E 2 295 ? 209.454 224.691 223.596 1.00 21.42  ? 364 LYS F CG    1 
ATOM   9569  C  CD    . LYS E 2 295 ? 210.801 223.989 223.678 1.00 22.55  ? 364 LYS F CD    1 
ATOM   9570  C  CE    . LYS E 2 295 ? 210.701 222.528 223.404 1.00 22.46  ? 364 LYS F CE    1 
ATOM   9571  N  NZ    . LYS E 2 295 ? 210.672 222.283 221.952 1.00 24.70  ? 364 LYS F NZ    1 
ATOM   9572  N  N     . ASN E 2 296 ? 205.491 224.503 224.106 1.00 22.07  ? 365 ASN F N     1 
ATOM   9573  C  CA    . ASN E 2 296 ? 204.483 224.222 223.097 1.00 25.40  ? 365 ASN F CA    1 
ATOM   9574  C  C     . ASN E 2 296 ? 203.289 225.172 223.219 1.00 27.99  ? 365 ASN F C     1 
ATOM   9575  O  O     . ASN E 2 296 ? 202.168 224.789 222.903 1.00 32.17  ? 365 ASN F O     1 
ATOM   9576  C  CB    . ASN E 2 296 ? 204.026 222.771 223.187 1.00 26.11  ? 365 ASN F CB    1 
ATOM   9577  C  CG    . ASN E 2 296 ? 205.126 221.792 222.844 1.00 28.36  ? 365 ASN F CG    1 
ATOM   9578  O  OD1   . ASN E 2 296 ? 205.918 222.036 221.929 1.00 30.21  ? 365 ASN F OD1   1 
ATOM   9579  N  ND2   . ASN E 2 296 ? 205.202 220.677 223.552 1.00 28.62  ? 365 ASN F ND2   1 
ATOM   9580  N  N     . ASN E 2 297 ? 203.528 226.397 223.697 1.00 31.29  ? 366 ASN F N     1 
ATOM   9581  C  CA    . ASN E 2 297 ? 202.546 227.477 223.717 1.00 35.85  ? 366 ASN F CA    1 
ATOM   9582  C  C     . ASN E 2 297 ? 201.428 227.230 224.728 1.00 35.70  ? 366 ASN F C     1 
ATOM   9583  O  O     . ASN E 2 297 ? 200.398 227.900 224.684 1.00 39.63  ? 366 ASN F O     1 
ATOM   9584  C  CB    . ASN E 2 297 ? 201.957 227.754 222.338 1.00 40.66  ? 366 ASN F CB    1 
ATOM   9585  C  CG    . ASN E 2 297 ? 203.034 227.959 221.299 1.00 46.73  ? 366 ASN F CG    1 
ATOM   9586  O  OD1   . ASN E 2 297 ? 203.775 228.948 221.364 1.00 48.72  ? 366 ASN F OD1   1 
ATOM   9587  N  ND2   . ASN E 2 297 ? 203.145 227.036 220.352 1.00 52.32  ? 366 ASN F ND2   1 
ATOM   9588  N  N     . GLY E 2 298 ? 201.631 226.292 225.650 1.00 33.80  ? 367 GLY F N     1 
ATOM   9589  C  CA    . GLY E 2 298 ? 200.714 226.131 226.764 1.00 34.53  ? 367 GLY F CA    1 
ATOM   9590  C  C     . GLY E 2 298 ? 200.836 227.292 227.748 1.00 33.09  ? 367 GLY F C     1 
ATOM   9591  O  O     . GLY E 2 298 ? 201.892 227.900 227.892 1.00 35.46  ? 367 GLY F O     1 
ATOM   9592  N  N     . ASN E 2 299 ? 199.736 227.595 228.430 1.00 32.47  ? 368 ASN F N     1 
ATOM   9593  C  CA    . ASN E 2 299 ? 199.742 228.645 229.428 1.00 31.29  ? 368 ASN F CA    1 
ATOM   9594  C  C     . ASN E 2 299 ? 200.115 228.053 230.785 1.00 29.09  ? 368 ASN F C     1 
ATOM   9595  O  O     . ASN E 2 299 ? 200.284 226.846 230.940 1.00 27.53  ? 368 ASN F O     1 
ATOM   9596  C  CB    . ASN E 2 299 ? 198.413 229.392 229.433 1.00 35.91  ? 368 ASN F CB    1 
ATOM   9597  C  CG    . ASN E 2 299 ? 197.241 228.534 229.846 1.00 40.10  ? 368 ASN F CG    1 
ATOM   9598  O  OD1   . ASN E 2 299 ? 197.408 227.418 230.345 1.00 42.90  ? 368 ASN F OD1   1 
ATOM   9599  N  ND2   . ASN E 2 299 ? 196.035 229.042 229.657 1.00 46.11  ? 368 ASN F ND2   1 
ATOM   9600  N  N     . TRP E 2 300 ? 200.207 228.921 231.788 1.00 27.46  ? 369 TRP F N     1 
ATOM   9601  C  CA    . TRP E 2 300 ? 200.658 228.502 233.100 1.00 28.55  ? 369 TRP F CA    1 
ATOM   9602  C  C     . TRP E 2 300 ? 199.662 227.561 233.767 1.00 30.86  ? 369 TRP F C     1 
ATOM   9603  O  O     . TRP E 2 300 ? 200.052 226.766 234.615 1.00 30.59  ? 369 TRP F O     1 
ATOM   9604  C  CB    . TRP E 2 300 ? 200.938 229.717 233.985 1.00 27.86  ? 369 TRP F CB    1 
ATOM   9605  C  CG    . TRP E 2 300 ? 202.266 230.350 233.689 1.00 28.18  ? 369 TRP F CG    1 
ATOM   9606  C  CD1   . TRP E 2 300 ? 202.505 231.555 233.100 1.00 29.09  ? 369 TRP F CD1   1 
ATOM   9607  C  CD2   . TRP E 2 300 ? 203.556 229.769 233.954 1.00 27.25  ? 369 TRP F CD2   1 
ATOM   9608  N  NE1   . TRP E 2 300 ? 203.854 231.772 232.993 1.00 28.22  ? 369 TRP F NE1   1 
ATOM   9609  C  CE2   . TRP E 2 300 ? 204.522 230.693 233.503 1.00 27.17  ? 369 TRP F CE2   1 
ATOM   9610  C  CE3   . TRP E 2 300 ? 203.981 228.568 234.530 1.00 25.79  ? 369 TRP F CE3   1 
ATOM   9611  C  CZ2   . TRP E 2 300 ? 205.887 230.453 233.625 1.00 26.92  ? 369 TRP F CZ2   1 
ATOM   9612  C  CZ3   . TRP E 2 300 ? 205.330 228.330 234.644 1.00 25.24  ? 369 TRP F CZ3   1 
ATOM   9613  C  CH2   . TRP E 2 300 ? 206.269 229.263 234.203 1.00 25.43  ? 369 TRP F CH2   1 
ATOM   9614  N  N     . GLN E 2 301 ? 198.383 227.632 233.395 1.00 33.57  ? 370 GLN F N     1 
ATOM   9615  C  CA    . GLN E 2 301 ? 197.394 226.752 233.998 1.00 36.73  ? 370 GLN F CA    1 
ATOM   9616  C  C     . GLN E 2 301 ? 197.568 225.320 233.492 1.00 33.45  ? 370 GLN F C     1 
ATOM   9617  O  O     . GLN E 2 301 ? 197.464 224.371 234.268 1.00 35.17  ? 370 GLN F O     1 
ATOM   9618  C  CB    . GLN E 2 301 ? 195.973 227.245 233.736 1.00 44.02  ? 370 GLN F CB    1 
ATOM   9619  C  CG    . GLN E 2 301 ? 194.944 226.569 234.637 1.00 51.59  ? 370 GLN F CG    1 
ATOM   9620  C  CD    . GLN E 2 301 ? 193.527 227.053 234.424 1.00 59.01  ? 370 GLN F CD    1 
ATOM   9621  O  OE1   . GLN E 2 301 ? 193.221 227.775 233.467 1.00 64.42  ? 370 GLN F OE1   1 
ATOM   9622  N  NE2   . GLN E 2 301 ? 192.642 226.644 235.324 1.00 60.37  ? 370 GLN F NE2   1 
ATOM   9623  N  N     . GLU E 2 302 ? 197.840 225.155 232.197 1.00 31.55  ? 371 GLU F N     1 
ATOM   9624  C  CA    . GLU E 2 302 ? 198.096 223.829 231.656 1.00 32.54  ? 371 GLU F CA    1 
ATOM   9625  C  C     . GLU E 2 302 ? 199.460 223.315 232.126 1.00 27.37  ? 371 GLU F C     1 
ATOM   9626  O  O     . GLU E 2 302 ? 199.589 222.139 232.468 1.00 27.30  ? 371 GLU F O     1 
ATOM   9627  C  CB    . GLU E 2 302 ? 198.053 223.831 230.130 1.00 36.80  ? 371 GLU F CB    1 
ATOM   9628  C  CG    . GLU E 2 302 ? 196.822 224.512 229.545 1.00 43.69  ? 371 GLU F CG    1 
ATOM   9629  C  CD    . GLU E 2 302 ? 196.934 224.683 228.038 1.00 49.45  ? 371 GLU F CD    1 
ATOM   9630  O  OE1   . GLU E 2 302 ? 196.767 223.682 227.305 1.00 54.53  ? 371 GLU F OE1   1 
ATOM   9631  O  OE2   . GLU E 2 302 ? 197.231 225.814 227.595 1.00 49.00  ? 371 GLU F OE2   1 
ATOM   9632  N  N     . ALA E 2 303 ? 200.474 224.191 232.133 1.00 23.67  ? 372 ALA F N     1 
ATOM   9633  C  CA    . ALA E 2 303 ? 201.828 223.785 232.485 1.00 22.99  ? 372 ALA F CA    1 
ATOM   9634  C  C     . ALA E 2 303 ? 201.889 223.305 233.931 1.00 22.36  ? 372 ALA F C     1 
ATOM   9635  O  O     . ALA E 2 303 ? 202.557 222.321 234.230 1.00 23.09  ? 372 ALA F O     1 
ATOM   9636  C  CB    . ALA E 2 303 ? 202.805 224.915 232.246 1.00 22.83  ? 372 ALA F CB    1 
ATOM   9637  N  N     . LEU E 2 304 ? 201.189 224.001 234.831 1.00 22.37  ? 373 LEU F N     1 
ATOM   9638  C  CA    . LEU E 2 304 ? 201.262 223.687 236.248 1.00 23.79  ? 373 LEU F CA    1 
ATOM   9639  C  C     . LEU E 2 304 ? 200.353 222.522 236.634 1.00 23.69  ? 373 LEU F C     1 
ATOM   9640  O  O     . LEU E 2 304 ? 200.257 222.203 237.816 1.00 25.21  ? 373 LEU F O     1 
ATOM   9641  C  CB    . LEU E 2 304 ? 200.945 224.928 237.078 1.00 24.27  ? 373 LEU F CB    1 
ATOM   9642  C  CG    . LEU E 2 304 ? 201.993 226.041 237.047 1.00 25.88  ? 373 LEU F CG    1 
ATOM   9643  C  CD1   . LEU E 2 304 ? 201.687 227.073 238.120 1.00 26.43  ? 373 LEU F CD1   1 
ATOM   9644  C  CD2   . LEU E 2 304 ? 203.404 225.501 237.203 1.00 26.32  ? 373 LEU F CD2   1 
ATOM   9645  N  N     . GLN E 2 305 ? 199.710 221.872 235.662 1.00 25.09  ? 374 GLN F N     1 
ATOM   9646  C  CA    . GLN E 2 305 ? 198.984 220.639 235.935 1.00 25.43  ? 374 GLN F CA    1 
ATOM   9647  C  C     . GLN E 2 305 ? 199.922 219.538 236.430 1.00 24.46  ? 374 GLN F C     1 
ATOM   9648  O  O     . GLN E 2 305 ? 199.492 218.644 237.158 1.00 25.17  ? 374 GLN F O     1 
ATOM   9649  C  CB    . GLN E 2 305 ? 198.256 220.131 234.692 1.00 29.56  ? 374 GLN F CB    1 
ATOM   9650  C  CG    . GLN E 2 305 ? 197.090 221.008 234.245 1.00 33.86  ? 374 GLN F CG    1 
ATOM   9651  C  CD    . GLN E 2 305 ? 196.060 221.213 235.336 1.00 37.21  ? 374 GLN F CD    1 
ATOM   9652  O  OE1   . GLN E 2 305 ? 195.638 220.262 236.004 1.00 38.50  ? 374 GLN F OE1   1 
ATOM   9653  N  NE2   . GLN E 2 305 ? 195.660 222.459 235.545 1.00 38.24  ? 374 GLN F NE2   1 
ATOM   9654  N  N     . PHE E 2 306 ? 201.204 219.597 236.050 1.00 21.79  ? 375 PHE F N     1 
ATOM   9655  C  CA    . PHE E 2 306 ? 202.165 218.577 236.438 1.00 21.01  ? 375 PHE F CA    1 
ATOM   9656  C  C     . PHE E 2 306 ? 202.702 218.791 237.845 1.00 21.17  ? 375 PHE F C     1 
ATOM   9657  O  O     . PHE E 2 306 ? 203.413 217.933 238.351 1.00 20.71  ? 375 PHE F O     1 
ATOM   9658  C  CB    . PHE E 2 306 ? 203.337 218.546 235.460 1.00 20.50  ? 375 PHE F CB    1 
ATOM   9659  C  CG    . PHE E 2 306 ? 202.875 218.313 234.036 1.00 20.05  ? 375 PHE F CG    1 
ATOM   9660  C  CD1   . PHE E 2 306 ? 202.421 217.059 233.643 1.00 20.68  ? 375 PHE F CD1   1 
ATOM   9661  C  CD2   . PHE E 2 306 ? 202.902 219.347 233.110 1.00 19.88  ? 375 PHE F CD2   1 
ATOM   9662  C  CE1   . PHE E 2 306 ? 201.995 216.853 232.343 1.00 20.50  ? 375 PHE F CE1   1 
ATOM   9663  C  CE2   . PHE E 2 306 ? 202.486 219.136 231.810 1.00 20.20  ? 375 PHE F CE2   1 
ATOM   9664  C  CZ    . PHE E 2 306 ? 202.018 217.892 231.433 1.00 20.82  ? 375 PHE F CZ    1 
ATOM   9665  N  N     . VAL E 2 307 ? 202.378 219.916 238.479 1.00 21.20  ? 376 VAL F N     1 
ATOM   9666  C  CA    . VAL E 2 307 ? 202.655 220.062 239.897 1.00 22.79  ? 376 VAL F CA    1 
ATOM   9667  C  C     . VAL E 2 307 ? 201.773 219.077 240.654 1.00 24.05  ? 376 VAL F C     1 
ATOM   9668  O  O     . VAL E 2 307 ? 200.581 218.974 240.366 1.00 26.26  ? 376 VAL F O     1 
ATOM   9669  C  CB    . VAL E 2 307 ? 202.407 221.506 240.351 1.00 24.00  ? 376 VAL F CB    1 
ATOM   9670  C  CG1   . VAL E 2 307 ? 202.704 221.677 241.829 1.00 24.80  ? 376 VAL F CG1   1 
ATOM   9671  C  CG2   . VAL E 2 307 ? 203.220 222.486 239.516 1.00 24.05  ? 376 VAL F CG2   1 
ATOM   9672  N  N     . PRO E 2 308 ? 202.312 218.292 241.612 1.00 24.39  ? 377 PRO F N     1 
ATOM   9673  C  CA    . PRO E 2 308 ? 201.483 217.328 242.339 1.00 25.93  ? 377 PRO F CA    1 
ATOM   9674  C  C     . PRO E 2 308 ? 200.272 217.988 242.992 1.00 26.69  ? 377 PRO F C     1 
ATOM   9675  O  O     . PRO E 2 308 ? 200.393 219.026 243.646 1.00 27.05  ? 377 PRO F O     1 
ATOM   9676  C  CB    . PRO E 2 308 ? 202.425 216.738 243.375 1.00 24.00  ? 377 PRO F CB    1 
ATOM   9677  C  CG    . PRO E 2 308 ? 203.798 216.953 242.790 1.00 24.13  ? 377 PRO F CG    1 
ATOM   9678  C  CD    . PRO E 2 308 ? 203.724 218.253 242.022 1.00 23.50  ? 377 PRO F CD    1 
ATOM   9679  N  N     . LYS E 2 309 ? 199.100 217.379 242.792 1.00 29.23  ? 378 LYS F N     1 
ATOM   9680  C  CA    . LYS E 2 309 ? 197.853 217.936 243.287 1.00 30.97  ? 378 LYS F CA    1 
ATOM   9681  C  C     . LYS E 2 309 ? 197.842 217.986 244.811 1.00 29.19  ? 378 LYS F C     1 
ATOM   9682  O  O     . LYS E 2 309 ? 197.166 218.831 245.392 1.00 32.67  ? 378 LYS F O     1 
ATOM   9683  C  CB    . LYS E 2 309 ? 196.665 217.113 242.786 1.00 35.32  ? 378 LYS F CB    1 
ATOM   9684  C  CG    . LYS E 2 309 ? 196.425 217.181 241.292 1.00 39.25  ? 378 LYS F CG    1 
ATOM   9685  C  CD    . LYS E 2 309 ? 196.195 218.594 240.788 1.00 43.08  ? 378 LYS F CD    1 
ATOM   9686  C  CE    . LYS E 2 309 ? 195.815 218.601 239.342 1.00 45.80  ? 378 LYS F CE    1 
ATOM   9687  N  NZ    . LYS E 2 309 ? 196.937 218.245 238.469 1.00 45.55  ? 378 LYS F NZ    1 
ATOM   9688  N  N     . ARG E 2 310 ? 198.584 217.088 245.462 1.00 26.62  ? 379 ARG F N     1 
ATOM   9689  C  CA    . ARG E 2 310 ? 198.587 217.025 246.911 1.00 25.65  ? 379 ARG F CA    1 
ATOM   9690  C  C     . ARG E 2 310 ? 199.209 218.274 247.533 1.00 26.81  ? 379 ARG F C     1 
ATOM   9691  O  O     . ARG E 2 310 ? 199.036 218.510 248.725 1.00 31.92  ? 379 ARG F O     1 
ATOM   9692  C  CB    . ARG E 2 310 ? 199.344 215.787 247.396 1.00 25.47  ? 379 ARG F CB    1 
ATOM   9693  C  CG    . ARG E 2 310 ? 200.852 215.955 247.491 1.00 24.64  ? 379 ARG F CG    1 
ATOM   9694  C  CD    . ARG E 2 310 ? 201.527 214.610 247.699 1.00 23.35  ? 379 ARG F CD    1 
ATOM   9695  N  NE    . ARG E 2 310 ? 202.975 214.777 247.848 1.00 23.73  ? 379 ARG F NE    1 
ATOM   9696  C  CZ    . ARG E 2 310 ? 203.908 214.572 246.921 1.00 23.13  ? 379 ARG F CZ    1 
ATOM   9697  N  NH1   . ARG E 2 310 ? 203.591 214.145 245.712 1.00 22.19  ? 379 ARG F NH1   1 
ATOM   9698  N  NH2   . ARG E 2 310 ? 205.171 214.774 247.232 1.00 23.85  ? 379 ARG F NH2   1 
ATOM   9699  N  N     . LYS E 2 311 ? 199.942 219.070 246.750 1.00 27.62  ? 380 LYS F N     1 
ATOM   9700  C  CA    . LYS E 2 311 ? 200.696 220.186 247.302 1.00 26.91  ? 380 LYS F CA    1 
ATOM   9701  C  C     . LYS E 2 311 ? 199.923 221.503 247.277 1.00 27.47  ? 380 LYS F C     1 
ATOM   9702  O  O     . LYS E 2 311 ? 200.380 222.474 247.872 1.00 26.96  ? 380 LYS F O     1 
ATOM   9703  C  CB    . LYS E 2 311 ? 202.020 220.342 246.551 1.00 26.05  ? 380 LYS F CB    1 
ATOM   9704  C  CG    . LYS E 2 311 ? 203.010 219.223 246.816 1.00 25.38  ? 380 LYS F CG    1 
ATOM   9705  C  CD    . LYS E 2 311 ? 204.409 219.542 246.298 1.00 24.94  ? 380 LYS F CD    1 
ATOM   9706  C  CE    . LYS E 2 311 ? 205.388 218.451 246.618 1.00 23.44  ? 380 LYS F CE    1 
ATOM   9707  N  NZ    . LYS E 2 311 ? 206.745 218.734 246.151 1.00 23.03  ? 380 LYS F NZ    1 
ATOM   9708  N  N     . HIS E 2 312 ? 198.775 221.556 246.594 1.00 29.13  ? 381 HIS F N     1 
ATOM   9709  C  CA    . HIS E 2 312 ? 198.012 222.790 246.491 1.00 30.92  ? 381 HIS F CA    1 
ATOM   9710  C  C     . HIS E 2 312 ? 196.516 222.488 246.457 1.00 34.68  ? 381 HIS F C     1 
ATOM   9711  O  O     . HIS E 2 312 ? 196.107 221.340 246.289 1.00 36.59  ? 381 HIS F O     1 
ATOM   9712  C  CB    . HIS E 2 312 ? 198.439 223.599 245.261 1.00 29.79  ? 381 HIS F CB    1 
ATOM   9713  C  CG    . HIS E 2 312 ? 198.246 222.889 243.964 1.00 30.50  ? 381 HIS F CG    1 
ATOM   9714  N  ND1   . HIS E 2 312 ? 197.102 223.008 243.208 1.00 32.13  ? 381 HIS F ND1   1 
ATOM   9715  C  CD2   . HIS E 2 312 ? 199.048 222.056 243.285 1.00 31.75  ? 381 HIS F CD2   1 
ATOM   9716  C  CE1   . HIS E 2 312 ? 197.217 222.268 242.113 1.00 32.18  ? 381 HIS F CE1   1 
ATOM   9717  N  NE2   . HIS E 2 312 ? 198.395 221.680 242.135 1.00 31.59  ? 381 HIS F NE2   1 
ATOM   9718  N  N     . THR E 2 313 ? 195.709 223.548 246.606 1.00 38.01  ? 382 THR F N     1 
ATOM   9719  C  CA    . THR E 2 313 ? 194.257 223.428 246.628 1.00 41.59  ? 382 THR F CA    1 
ATOM   9720  C  C     . THR E 2 313 ? 193.634 224.037 245.376 1.00 43.87  ? 382 THR F C     1 
ATOM   9721  O  O     . THR E 2 313 ? 192.428 224.282 245.350 1.00 48.39  ? 382 THR F O     1 
ATOM   9722  C  CB    . THR E 2 313 ? 193.676 224.087 247.878 1.00 41.96  ? 382 THR F CB    1 
ATOM   9723  O  OG1   . THR E 2 313 ? 194.000 225.475 247.881 1.00 42.97  ? 382 THR F OG1   1 
ATOM   9724  C  CG2   . THR E 2 313 ? 194.190 223.434 249.143 1.00 42.61  ? 382 THR F CG2   1 
ATOM   9725  N  N     . GLY E 2 314 ? 194.442 224.281 244.339 1.00 43.61  ? 383 GLY F N     1 
ATOM   9726  C  CA    . GLY E 2 314 ? 193.893 224.692 243.055 1.00 43.87  ? 383 GLY F CA    1 
ATOM   9727  C  C     . GLY E 2 314 ? 194.554 225.952 242.506 1.00 44.20  ? 383 GLY F C     1 
ATOM   9728  O  O     . GLY E 2 314 ? 195.493 226.483 243.085 1.00 45.67  ? 383 GLY F O     1 
ATOM   9729  N  N     . PHE E 2 315 ? 194.046 226.411 241.361 1.00 49.42  ? 384 PHE F N     1 
ATOM   9730  C  CA    . PHE E 2 315 ? 194.615 227.538 240.646 1.00 54.12  ? 384 PHE F CA    1 
ATOM   9731  C  C     . PHE E 2 315 ? 193.907 228.821 241.061 1.00 57.84  ? 384 PHE F C     1 
ATOM   9732  O  O     . PHE E 2 315 ? 192.752 229.033 240.704 1.00 65.04  ? 384 PHE F O     1 
ATOM   9733  C  CB    . PHE E 2 315 ? 194.471 227.329 239.139 1.00 57.02  ? 384 PHE F CB    1 
ATOM   9734  C  CG    . PHE E 2 315 ? 195.526 226.407 238.564 1.00 61.09  ? 384 PHE F CG    1 
ATOM   9735  C  CD1   . PHE E 2 315 ? 195.344 225.030 238.580 1.00 65.38  ? 384 PHE F CD1   1 
ATOM   9736  C  CD2   . PHE E 2 315 ? 196.694 226.926 238.019 1.00 63.50  ? 384 PHE F CD2   1 
ATOM   9737  C  CE1   . PHE E 2 315 ? 196.313 224.188 238.065 1.00 65.80  ? 384 PHE F CE1   1 
ATOM   9738  C  CE2   . PHE E 2 315 ? 197.659 226.080 237.502 1.00 65.48  ? 384 PHE F CE2   1 
ATOM   9739  C  CZ    . PHE E 2 315 ? 197.462 224.713 237.522 1.00 66.20  ? 384 PHE F CZ    1 
ATOM   9740  N  N     . LEU E 2 316 ? 194.614 229.679 241.799 1.00 58.65  ? 385 LEU F N     1 
ATOM   9741  C  CA    . LEU E 2 316 ? 194.044 230.940 242.252 1.00 61.35  ? 385 LEU F CA    1 
ATOM   9742  C  C     . LEU E 2 316 ? 194.120 232.003 241.139 1.00 63.99  ? 385 LEU F C     1 
ATOM   9743  O  O     . LEU E 2 316 ? 194.586 231.680 240.021 1.00 66.13  ? 385 LEU F O     1 
ATOM   9744  C  CB    . LEU E 2 316 ? 194.723 231.411 243.542 1.00 60.39  ? 385 LEU F CB    1 
ATOM   9745  C  CG    . LEU E 2 316 ? 196.229 231.704 243.500 1.00 58.16  ? 385 LEU F CG    1 
ATOM   9746  C  CD1   . LEU E 2 316 ? 196.574 233.106 243.037 1.00 60.45  ? 385 LEU F CD1   1 
ATOM   9747  C  CD2   . LEU E 2 316 ? 196.826 231.460 244.881 1.00 58.43  ? 385 LEU F CD2   1 
ATOM   9748  P  P     . U   F 3 1   ? 212.723 230.414 268.884 1.00 160.98 ? 2   U   T P     1 
ATOM   9749  O  OP1   . U   F 3 1   ? 212.934 229.529 267.682 1.00 161.28 ? 2   U   T OP1   1 
ATOM   9750  O  OP2   . U   F 3 1   ? 213.201 229.830 270.250 1.00 163.93 ? 2   U   T OP2   1 
ATOM   9751  O  "O5'" . U   F 3 1   ? 211.129 230.676 269.034 1.00 138.76 ? 2   U   T "O5'" 1 
ATOM   9752  C  "C5'" . U   F 3 1   ? 210.661 231.847 269.753 1.00 125.26 ? 2   U   T "C5'" 1 
ATOM   9753  C  "C4'" . U   F 3 1   ? 209.163 231.774 269.933 1.00 116.08 ? 2   U   T "C4'" 1 
ATOM   9754  O  "O4'" . U   F 3 1   ? 208.487 232.756 269.097 1.00 110.44 ? 2   U   T "O4'" 1 
ATOM   9755  C  "C3'" . U   F 3 1   ? 208.492 230.453 269.540 1.00 110.11 ? 2   U   T "C3'" 1 
ATOM   9756  O  "O3'" . U   F 3 1   ? 208.645 229.457 270.537 1.00 108.63 ? 2   U   T "O3'" 1 
ATOM   9757  C  "C2'" . U   F 3 1   ? 207.037 230.898 269.377 1.00 106.60 ? 2   U   T "C2'" 1 
ATOM   9758  O  "O2'" . U   F 3 1   ? 206.374 231.047 270.614 1.00 106.24 ? 2   U   T "O2'" 1 
ATOM   9759  C  "C1'" . U   F 3 1   ? 207.205 232.278 268.737 1.00 104.69 ? 2   U   T "C1'" 1 
ATOM   9760  N  N1    . U   F 3 1   ? 207.080 232.243 267.261 1.00 96.87  ? 2   U   T N1    1 
ATOM   9761  C  C2    . U   F 3 1   ? 205.841 232.538 266.726 1.00 93.01  ? 2   U   T C2    1 
ATOM   9762  O  O2    . U   F 3 1   ? 204.876 232.830 267.415 1.00 95.60  ? 2   U   T O2    1 
ATOM   9763  N  N3    . U   F 3 1   ? 205.772 232.492 265.357 1.00 86.57  ? 2   U   T N3    1 
ATOM   9764  C  C4    . U   F 3 1   ? 206.792 232.180 264.481 1.00 88.30  ? 2   U   T C4    1 
ATOM   9765  O  O4    . U   F 3 1   ? 206.574 232.176 263.270 1.00 84.51  ? 2   U   T O4    1 
ATOM   9766  C  C5    . U   F 3 1   ? 208.047 231.887 265.108 1.00 91.93  ? 2   U   T C5    1 
ATOM   9767  C  C6    . U   F 3 1   ? 208.141 231.922 266.446 1.00 93.04  ? 2   U   T C6    1 
ATOM   9768  P  P     . A   F 3 2   ? 208.574 227.904 270.141 1.00 104.26 ? 3   A   T P     1 
ATOM   9769  O  OP1   . A   F 3 2   ? 209.037 227.074 271.289 1.00 108.77 ? 3   A   T OP1   1 
ATOM   9770  O  OP2   . A   F 3 2   ? 209.232 227.720 268.818 1.00 103.67 ? 3   A   T OP2   1 
ATOM   9771  O  "O5'" . A   F 3 2   ? 207.014 227.660 269.898 1.00 92.93  ? 3   A   T "O5'" 1 
ATOM   9772  C  "C5'" . A   F 3 2   ? 206.087 227.835 270.997 1.00 88.18  ? 3   A   T "C5'" 1 
ATOM   9773  C  "C4'" . A   F 3 2   ? 204.669 227.799 270.479 1.00 84.00  ? 3   A   T "C4'" 1 
ATOM   9774  O  "O4'" . A   F 3 2   ? 204.423 228.928 269.603 1.00 78.84  ? 3   A   T "O4'" 1 
ATOM   9775  C  "C3'" . A   F 3 2   ? 204.297 226.590 269.621 1.00 81.41  ? 3   A   T "C3'" 1 
ATOM   9776  O  "O3'" . A   F 3 2   ? 203.992 225.456 270.415 1.00 82.23  ? 3   A   T "O3'" 1 
ATOM   9777  C  "C2'" . A   F 3 2   ? 203.079 227.127 268.867 1.00 78.88  ? 3   A   T "C2'" 1 
ATOM   9778  O  "O2'" . A   F 3 2   ? 201.904 227.100 269.647 1.00 78.49  ? 3   A   T "O2'" 1 
ATOM   9779  C  "C1'" . A   F 3 2   ? 203.494 228.571 268.601 1.00 74.09  ? 3   A   T "C1'" 1 
ATOM   9780  N  N9    . A   F 3 2   ? 204.100 228.774 267.288 1.00 67.38  ? 3   A   T N9    1 
ATOM   9781  C  C8    . A   F 3 2   ? 205.431 228.933 266.984 1.00 65.37  ? 3   A   T C8    1 
ATOM   9782  N  N7    . A   F 3 2   ? 205.661 229.104 265.705 1.00 62.95  ? 3   A   T N7    1 
ATOM   9783  C  C5    . A   F 3 2   ? 204.402 229.047 265.126 1.00 57.00  ? 3   A   T C5    1 
ATOM   9784  C  C6    . A   F 3 2   ? 203.969 229.155 263.791 1.00 54.61  ? 3   A   T C6    1 
ATOM   9785  N  N6    . A   F 3 2   ? 204.792 229.353 262.765 1.00 55.53  ? 3   A   T N6    1 
ATOM   9786  N  N1    . A   F 3 2   ? 202.638 229.051 263.555 1.00 53.48  ? 3   A   T N1    1 
ATOM   9787  C  C2    . A   F 3 2   ? 201.816 228.854 264.594 1.00 55.42  ? 3   A   T C2    1 
ATOM   9788  N  N3    . A   F 3 2   ? 202.109 228.739 265.886 1.00 57.73  ? 3   A   T N3    1 
ATOM   9789  C  C4    . A   F 3 2   ? 203.433 228.843 266.090 1.00 59.37  ? 3   A   T C4    1 
ATOM   9790  P  P     . A   F 3 3   ? 204.334 223.989 269.868 1.00 82.12  ? 4   A   T P     1 
ATOM   9791  O  OP1   . A   F 3 3   ? 204.466 223.041 271.010 1.00 85.37  ? 4   A   T OP1   1 
ATOM   9792  O  OP2   . A   F 3 3   ? 205.460 224.106 268.900 1.00 84.00  ? 4   A   T OP2   1 
ATOM   9793  O  "O5'" . A   F 3 3   ? 203.039 223.589 269.023 1.00 75.42  ? 4   A   T "O5'" 1 
ATOM   9794  C  "C5'" . A   F 3 3   ? 201.730 223.777 269.606 1.00 70.40  ? 4   A   T "C5'" 1 
ATOM   9795  C  "C4'" . A   F 3 3   ? 200.697 223.854 268.509 1.00 67.87  ? 4   A   T "C4'" 1 
ATOM   9796  O  "O4'" . A   F 3 3   ? 200.891 225.064 267.737 1.00 65.04  ? 4   A   T "O4'" 1 
ATOM   9797  C  "C3'" . A   F 3 3   ? 200.749 222.740 267.463 1.00 68.03  ? 4   A   T "C3'" 1 
ATOM   9798  O  "O3'" . A   F 3 3   ? 200.082 221.569 267.904 1.00 69.75  ? 4   A   T "O3'" 1 
ATOM   9799  C  "C2'" . A   F 3 3   ? 200.049 223.407 266.277 1.00 63.91  ? 4   A   T "C2'" 1 
ATOM   9800  O  "O2'" . A   F 3 3   ? 198.643 223.402 266.399 1.00 64.25  ? 4   A   T "O2'" 1 
ATOM   9801  C  "C1'" . A   F 3 3   ? 200.569 224.837 266.380 1.00 59.76  ? 4   A   T "C1'" 1 
ATOM   9802  N  N9    . A   F 3 3   ? 201.747 225.100 265.559 1.00 52.55  ? 4   A   T N9    1 
ATOM   9803  C  C8    . A   F 3 3   ? 203.064 225.093 265.945 1.00 49.83  ? 4   A   T C8    1 
ATOM   9804  N  N7    . A   F 3 3   ? 203.896 225.381 264.972 1.00 46.96  ? 4   A   T N7    1 
ATOM   9805  C  C5    . A   F 3 3   ? 203.075 225.591 263.873 1.00 44.53  ? 4   A   T C5    1 
ATOM   9806  C  C6    . A   F 3 3   ? 203.350 225.928 262.534 1.00 41.68  ? 4   A   T C6    1 
ATOM   9807  N  N6    . A   F 3 3   ? 204.575 226.124 262.053 1.00 40.02  ? 4   A   T N6    1 
ATOM   9808  N  N1    . A   F 3 3   ? 202.295 226.057 261.697 1.00 41.54  ? 4   A   T N1    1 
ATOM   9809  C  C2    . A   F 3 3   ? 201.063 225.862 262.181 1.00 45.52  ? 4   A   T C2    1 
ATOM   9810  N  N3    . A   F 3 3   ? 200.685 225.546 263.415 1.00 49.39  ? 4   A   T N3    1 
ATOM   9811  C  C4    . A   F 3 3   ? 201.750 225.420 264.224 1.00 48.26  ? 4   A   T C4    1 
ATOM   9812  P  P     . A   F 3 4   ? 200.511 220.139 267.315 1.00 71.74  ? 5   A   T P     1 
ATOM   9813  O  OP1   . A   F 3 4   ? 200.714 219.177 268.435 1.00 77.36  ? 5   A   T OP1   1 
ATOM   9814  O  OP2   . A   F 3 4   ? 201.637 220.362 266.366 1.00 69.38  ? 5   A   T OP2   1 
ATOM   9815  O  "O5'" . A   F 3 4   ? 199.210 219.707 266.491 1.00 70.17  ? 5   A   T "O5'" 1 
ATOM   9816  C  "C5'" . A   F 3 4   ? 199.375 218.935 265.277 1.00 67.77  ? 5   A   T "C5'" 1 
ATOM   9817  C  "C4'" . A   F 3 4   ? 198.863 219.725 264.100 1.00 64.03  ? 5   A   T "C4'" 1 
ATOM   9818  O  "O4'" . A   F 3 4   ? 199.422 221.062 264.115 1.00 59.69  ? 5   A   T "O4'" 1 
ATOM   9819  C  "C3'" . A   F 3 4   ? 199.258 219.176 262.728 1.00 61.42  ? 5   A   T "C3'" 1 
ATOM   9820  O  "O3'" . A   F 3 4   ? 198.380 218.145 262.304 1.00 64.23  ? 5   A   T "O3'" 1 
ATOM   9821  C  "C2'" . A   F 3 4   ? 199.167 220.423 261.850 1.00 57.40  ? 5   A   T "C2'" 1 
ATOM   9822  O  "O2'" . A   F 3 4   ? 197.842 220.700 261.457 1.00 60.05  ? 5   A   T "O2'" 1 
ATOM   9823  C  "C1'" . A   F 3 4   ? 199.672 221.509 262.797 1.00 54.57  ? 5   A   T "C1'" 1 
ATOM   9824  N  N9    . A   F 3 4   ? 201.094 221.803 262.661 1.00 46.91  ? 5   A   T N9    1 
ATOM   9825  C  C8    . A   F 3 4   ? 202.078 221.586 263.594 1.00 44.13  ? 5   A   T C8    1 
ATOM   9826  N  N7    . A   F 3 4   ? 203.269 221.962 263.203 1.00 42.44  ? 5   A   T N7    1 
ATOM   9827  C  C5    . A   F 3 4   ? 203.062 222.467 261.930 1.00 41.56  ? 5   A   T C5    1 
ATOM   9828  C  C6    . A   F 3 4   ? 203.940 223.019 260.984 1.00 38.54  ? 5   A   T C6    1 
ATOM   9829  N  N6    . A   F 3 4   ? 205.246 223.161 261.189 1.00 38.02  ? 5   A   T N6    1 
ATOM   9830  N  N1    . A   F 3 4   ? 203.410 223.425 259.807 1.00 37.84  ? 5   A   T N1    1 
ATOM   9831  C  C2    . A   F 3 4   ? 202.095 223.279 259.608 1.00 37.41  ? 5   A   T C2    1 
ATOM   9832  N  N3    . A   F 3 4   ? 201.175 222.772 260.423 1.00 41.66  ? 5   A   T N3    1 
ATOM   9833  C  C4    . A   F 3 4   ? 201.725 222.378 261.583 1.00 43.43  ? 5   A   T C4    1 
ATOM   9834  P  P     . U   F 3 5   ? 198.877 216.618 262.308 1.00 70.04  ? 6   U   T P     1 
ATOM   9835  O  OP1   . U   F 3 5   ? 197.746 215.737 262.717 1.00 74.37  ? 6   U   T OP1   1 
ATOM   9836  O  OP2   . U   F 3 5   ? 200.158 216.541 263.070 1.00 62.78  ? 6   U   T OP2   1 
ATOM   9837  O  "O5'" . U   F 3 5   ? 199.156 216.356 260.754 1.00 65.57  ? 6   U   T "O5'" 1 
ATOM   9838  C  "C5'" . U   F 3 5   ? 200.504 216.526 260.259 1.00 58.09  ? 6   U   T "C5'" 1 
ATOM   9839  C  "C4'" . U   F 3 5   ? 200.509 217.555 259.159 1.00 50.49  ? 6   U   T "C4'" 1 
ATOM   9840  O  "O4'" . U   F 3 5   ? 200.939 218.836 259.683 1.00 47.03  ? 6   U   T "O4'" 1 
ATOM   9841  C  "C3'" . U   F 3 5   ? 201.489 217.263 258.019 1.00 46.80  ? 6   U   T "C3'" 1 
ATOM   9842  O  "O3'" . U   F 3 5   ? 200.914 216.411 257.042 1.00 43.25  ? 6   U   T "O3'" 1 
ATOM   9843  C  "C2'" . U   F 3 5   ? 201.774 218.663 257.474 1.00 44.86  ? 6   U   T "C2'" 1 
ATOM   9844  O  "O2'" . U   F 3 5   ? 200.752 219.121 256.616 1.00 44.88  ? 6   U   T "O2'" 1 
ATOM   9845  C  "C1'" . U   F 3 5   ? 201.777 219.495 258.756 1.00 42.85  ? 6   U   T "C1'" 1 
ATOM   9846  N  N1    . U   F 3 5   ? 203.113 219.643 259.370 1.00 39.54  ? 6   U   T N1    1 
ATOM   9847  C  C2    . U   F 3 5   ? 204.063 220.405 258.708 1.00 37.92  ? 6   U   T C2    1 
ATOM   9848  O  O2    . U   F 3 5   ? 203.859 220.950 257.632 1.00 38.81  ? 6   U   T O2    1 
ATOM   9849  N  N3    . U   F 3 5   ? 205.271 220.499 259.350 1.00 37.27  ? 6   U   T N3    1 
ATOM   9850  C  C4    . U   F 3 5   ? 205.619 219.933 260.561 1.00 37.97  ? 6   U   T C4    1 
ATOM   9851  O  O4    . U   F 3 5   ? 206.750 220.111 261.012 1.00 40.69  ? 6   U   T O4    1 
ATOM   9852  C  C5    . U   F 3 5   ? 204.580 219.171 261.184 1.00 38.06  ? 6   U   T C5    1 
ATOM   9853  C  C6    . U   F 3 5   ? 203.391 219.056 260.580 1.00 38.35  ? 6   U   T C6    1 
ATOM   9854  P  P     . A   F 3 6   ? 201.680 215.074 256.599 1.00 41.16  ? 7   A   T P     1 
ATOM   9855  O  OP1   . A   F 3 6   ? 200.777 214.241 255.755 1.00 43.96  ? 7   A   T OP1   1 
ATOM   9856  O  OP2   . A   F 3 6   ? 202.321 214.461 257.798 1.00 43.74  ? 7   A   T OP2   1 
ATOM   9857  O  "O5'" . A   F 3 6   ? 202.869 215.628 255.689 1.00 37.53  ? 7   A   T "O5'" 1 
ATOM   9858  C  "C5'" . A   F 3 6   ? 202.549 216.450 254.537 1.00 34.37  ? 7   A   T "C5'" 1 
ATOM   9859  C  "C4'" . A   F 3 6   ? 203.809 216.764 253.771 1.00 31.62  ? 7   A   T "C4'" 1 
ATOM   9860  O  "O4'" . A   F 3 6   ? 204.670 217.610 254.577 1.00 30.74  ? 7   A   T "O4'" 1 
ATOM   9861  C  "C3'" . A   F 3 6   ? 204.668 215.557 253.384 1.00 30.13  ? 7   A   T "C3'" 1 
ATOM   9862  O  "O3'" . A   F 3 6   ? 205.308 215.791 252.142 1.00 31.35  ? 7   A   T "O3'" 1 
ATOM   9863  C  "C2'" . A   F 3 6   ? 205.702 215.505 254.506 1.00 28.99  ? 7   A   T "C2'" 1 
ATOM   9864  O  "O2'" . A   F 3 6   ? 206.905 214.868 254.132 1.00 31.31  ? 7   A   T "O2'" 1 
ATOM   9865  C  "C1'" . A   F 3 6   ? 205.919 216.990 254.772 1.00 29.71  ? 7   A   T "C1'" 1 
ATOM   9866  N  N9    . A   F 3 6   ? 206.368 217.286 256.124 1.00 28.35  ? 7   A   T N9    1 
ATOM   9867  C  C8    . A   F 3 6   ? 205.701 216.996 257.287 1.00 28.13  ? 7   A   T C8    1 
ATOM   9868  N  N7    . A   F 3 6   ? 206.340 217.372 258.366 1.00 29.55  ? 7   A   T N7    1 
ATOM   9869  C  C5    . A   F 3 6   ? 207.504 217.947 257.883 1.00 29.68  ? 7   A   T C5    1 
ATOM   9870  C  C6    . A   F 3 6   ? 208.598 218.546 258.527 1.00 30.34  ? 7   A   T C6    1 
ATOM   9871  N  N6    . A   F 3 6   ? 208.702 218.664 259.846 1.00 33.95  ? 7   A   T N6    1 
ATOM   9872  N  N1    . A   F 3 6   ? 209.596 219.024 257.746 1.00 30.97  ? 7   A   T N1    1 
ATOM   9873  C  C2    . A   F 3 6   ? 209.487 218.906 256.418 1.00 28.16  ? 7   A   T C2    1 
ATOM   9874  N  N3    . A   F 3 6   ? 208.506 218.369 255.704 1.00 28.94  ? 7   A   T N3    1 
ATOM   9875  C  C4    . A   F 3 6   ? 207.533 217.902 256.501 1.00 28.99  ? 7   A   T C4    1 
ATOM   9876  P  P     . U   F 3 7   ? 204.746 215.134 250.795 1.00 31.23  ? 8   U   T P     1 
ATOM   9877  O  OP1   . U   F 3 7   ? 205.739 215.372 249.712 1.00 34.98  ? 8   U   T OP1   1 
ATOM   9878  O  OP2   . U   F 3 7   ? 203.340 215.572 250.575 1.00 33.86  ? 8   U   T OP2   1 
ATOM   9879  O  "O5'" . U   F 3 7   ? 204.693 213.574 251.129 1.00 29.14  ? 8   U   T "O5'" 1 
ATOM   9880  C  "C5'" . U   F 3 7   ? 205.903 212.905 251.543 1.00 28.93  ? 8   U   T "C5'" 1 
ATOM   9881  C  "C4'" . U   F 3 7   ? 206.008 211.544 250.897 1.00 29.60  ? 8   U   T "C4'" 1 
ATOM   9882  O  "O4'" . U   F 3 7   ? 204.822 210.750 251.163 1.00 30.08  ? 8   U   T "O4'" 1 
ATOM   9883  C  "C3'" . U   F 3 7   ? 206.173 211.540 249.369 1.00 29.10  ? 8   U   T "C3'" 1 
ATOM   9884  O  "O3'" . U   F 3 7   ? 207.064 210.503 248.999 1.00 28.77  ? 8   U   T "O3'" 1 
ATOM   9885  C  "C2'" . U   F 3 7   ? 204.760 211.232 248.868 1.00 30.27  ? 8   U   T "C2'" 1 
ATOM   9886  O  "O2'" . U   F 3 7   ? 204.742 210.629 247.590 1.00 30.51  ? 8   U   T "O2'" 1 
ATOM   9887  C  "C1'" . U   F 3 7   ? 204.322 210.243 249.948 1.00 32.69  ? 8   U   T "C1'" 1 
ATOM   9888  N  N1    . U   F 3 7   ? 202.858 210.101 250.047 1.00 38.70  ? 8   U   T N1    1 
ATOM   9889  C  C2    . U   F 3 7   ? 202.322 208.880 249.688 1.00 43.45  ? 8   U   T C2    1 
ATOM   9890  O  O2    . U   F 3 7   ? 203.010 207.944 249.313 1.00 43.88  ? 8   U   T O2    1 
ATOM   9891  N  N3    . U   F 3 7   ? 200.958 208.796 249.786 1.00 47.90  ? 8   U   T N3    1 
ATOM   9892  C  C4    . U   F 3 7   ? 200.093 209.793 250.190 1.00 50.65  ? 8   U   T C4    1 
ATOM   9893  O  O4    . U   F 3 7   ? 198.885 209.568 250.232 1.00 55.47  ? 8   U   T O4    1 
ATOM   9894  C  C5    . U   F 3 7   ? 200.725 211.030 250.542 1.00 47.31  ? 8   U   T C5    1 
ATOM   9895  C  C6    . U   F 3 7   ? 202.059 211.138 250.460 1.00 42.61  ? 8   U   T C6    1 
ATOM   9896  P  P     . A   F 3 8   ? 208.585 210.833 248.616 1.00 27.29  ? 9   A   T P     1 
ATOM   9897  O  OP1   . A   F 3 8   ? 209.260 209.580 248.184 1.00 29.80  ? 9   A   T OP1   1 
ATOM   9898  O  OP2   . A   F 3 8   ? 209.219 211.658 249.679 1.00 28.80  ? 9   A   T OP2   1 
ATOM   9899  O  "O5'" . A   F 3 8   ? 208.413 211.803 247.351 1.00 26.05  ? 9   A   T "O5'" 1 
ATOM   9900  C  "C5'" . A   F 3 8   ? 207.862 211.260 246.119 1.00 24.13  ? 9   A   T "C5'" 1 
ATOM   9901  C  "C4'" . A   F 3 8   ? 208.869 211.403 245.012 1.00 23.45  ? 9   A   T "C4'" 1 
ATOM   9902  O  "O4'" . A   F 3 8   ? 209.382 212.761 245.004 1.00 22.22  ? 9   A   T "O4'" 1 
ATOM   9903  C  "C3'" . A   F 3 8   ? 210.095 210.489 245.109 1.00 22.28  ? 9   A   T "C3'" 1 
ATOM   9904  O  "O3'" . A   F 3 8   ? 210.555 210.186 243.800 1.00 22.10  ? 9   A   T "O3'" 1 
ATOM   9905  C  "C2'" . A   F 3 8   ? 211.111 211.398 245.798 1.00 22.22  ? 9   A   T "C2'" 1 
ATOM   9906  O  "O2'" . A   F 3 8   ? 212.451 210.994 245.587 1.00 22.00  ? 9   A   T "O2'" 1 
ATOM   9907  C  "C1'" . A   F 3 8   ? 210.778 212.726 245.123 1.00 21.70  ? 9   A   T "C1'" 1 
ATOM   9908  N  N9    . A   F 3 8   ? 211.202 213.877 245.900 1.00 24.24  ? 9   A   T N9    1 
ATOM   9909  C  C8    . A   F 3 8   ? 210.810 214.212 247.176 1.00 24.77  ? 9   A   T C8    1 
ATOM   9910  N  N7    . A   F 3 8   ? 211.432 215.263 247.640 1.00 26.19  ? 9   A   T N7    1 
ATOM   9911  C  C5    . A   F 3 8   ? 212.281 215.644 246.611 1.00 28.02  ? 9   A   T C5    1 
ATOM   9912  C  C6    . A   F 3 8   ? 213.204 216.697 246.485 1.00 31.24  ? 9   A   T C6    1 
ATOM   9913  N  N6    . A   F 3 8   ? 213.438 217.595 247.440 1.00 33.34  ? 9   A   T N6    1 
ATOM   9914  N  N1    . A   F 3 8   ? 213.893 216.783 245.322 1.00 30.81  ? 9   A   T N1    1 
ATOM   9915  C  C2    . A   F 3 8   ? 213.652 215.882 244.361 1.00 29.58  ? 9   A   T C2    1 
ATOM   9916  N  N3    . A   F 3 8   ? 212.817 214.847 244.369 1.00 27.94  ? 9   A   T N3    1 
ATOM   9917  C  C4    . A   F 3 8   ? 212.147 214.794 245.531 1.00 26.65  ? 9   A   T C4    1 
ATOM   9918  P  P     . G   F 3 9   ? 209.918 208.992 242.948 1.00 20.19  ? 10  G   T P     1 
ATOM   9919  O  OP1   . G   F 3 9   ? 209.090 208.140 243.847 1.00 23.97  ? 10  G   T OP1   1 
ATOM   9920  O  OP2   . G   F 3 9   ? 210.980 208.345 242.134 1.00 23.90  ? 10  G   T OP2   1 
ATOM   9921  O  "O5'" . G   F 3 9   ? 208.895 209.723 241.971 1.00 20.24  ? 10  G   T "O5'" 1 
ATOM   9922  C  "C5'" . G   F 3 9   ? 209.228 211.010 241.407 1.00 18.95  ? 10  G   T "C5'" 1 
ATOM   9923  C  "C4'" . G   F 3 9   ? 208.162 211.405 240.420 1.00 18.88  ? 10  G   T "C4'" 1 
ATOM   9924  O  "O4'" . G   F 3 9   ? 208.162 210.487 239.294 1.00 18.58  ? 10  G   T "O4'" 1 
ATOM   9925  C  "C3'" . G   F 3 9   ? 206.729 211.343 240.945 1.00 18.44  ? 10  G   T "C3'" 1 
ATOM   9926  O  "O3'" . G   F 3 9   ? 206.336 212.514 241.635 1.00 18.73  ? 10  G   T "O3'" 1 
ATOM   9927  C  "C2'" . G   F 3 9   ? 205.940 211.155 239.648 1.00 18.32  ? 10  G   T "C2'" 1 
ATOM   9928  O  "O2'" . G   F 3 9   ? 205.808 212.344 238.900 1.00 18.28  ? 10  G   T "O2'" 1 
ATOM   9929  C  "C1'" . G   F 3 9   ? 206.840 210.171 238.913 1.00 18.57  ? 10  G   T "C1'" 1 
ATOM   9930  N  N9    . G   F 3 9   ? 206.579 208.780 239.265 1.00 20.26  ? 10  G   T N9    1 
ATOM   9931  C  C8    . G   F 3 9   ? 207.473 207.895 239.813 1.00 19.92  ? 10  G   T C8    1 
ATOM   9932  N  N7    . G   F 3 9   ? 206.972 206.700 239.999 1.00 20.64  ? 10  G   T N7    1 
ATOM   9933  C  C5    . G   F 3 9   ? 205.663 206.804 239.555 1.00 21.04  ? 10  G   T C5    1 
ATOM   9934  C  C6    . G   F 3 9   ? 204.629 205.837 239.520 1.00 21.27  ? 10  G   T C6    1 
ATOM   9935  O  O6    . G   F 3 9   ? 204.677 204.657 239.887 1.00 23.05  ? 10  G   T O6    1 
ATOM   9936  N  N1    . G   F 3 9   ? 203.453 206.365 238.983 1.00 21.64  ? 10  G   T N1    1 
ATOM   9937  C  C2    . G   F 3 9   ? 203.291 207.650 238.548 1.00 22.26  ? 10  G   T C2    1 
ATOM   9938  N  N2    . G   F 3 9   ? 202.088 207.977 238.067 1.00 23.92  ? 10  G   T N2    1 
ATOM   9939  N  N3    . G   F 3 9   ? 204.258 208.567 238.587 1.00 23.23  ? 10  G   T N3    1 
ATOM   9940  C  C4    . G   F 3 9   ? 205.411 208.076 239.094 1.00 21.57  ? 10  G   T C4    1 
ATOM   9941  P  P     . U   F 3 10  ? 205.391 212.412 242.927 1.00 18.45  ? 11  U   T P     1 
ATOM   9942  O  OP1   . U   F 3 10  ? 205.435 213.731 243.622 1.00 23.64  ? 11  U   T OP1   1 
ATOM   9943  O  OP2   . U   F 3 10  ? 205.747 211.190 243.696 1.00 20.60  ? 11  U   T OP2   1 
ATOM   9944  O  "O5'" . U   F 3 10  ? 203.968 212.127 242.285 1.00 19.67  ? 11  U   T "O5'" 1 
ATOM   9945  C  "C5'" . U   F 3 10  ? 203.376 213.099 241.401 1.00 21.09  ? 11  U   T "C5'" 1 
ATOM   9946  C  "C4'" . U   F 3 10  ? 202.062 212.568 240.888 1.00 22.81  ? 11  U   T "C4'" 1 
ATOM   9947  O  "O4'" . U   F 3 10  ? 202.285 211.338 240.153 1.00 23.80  ? 11  U   T "O4'" 1 
ATOM   9948  C  "C3'" . U   F 3 10  ? 201.045 212.170 241.963 1.00 24.12  ? 11  U   T "C3'" 1 
ATOM   9949  O  "O3'" . U   F 3 10  ? 200.319 213.286 242.447 1.00 26.73  ? 11  U   T "O3'" 1 
ATOM   9950  C  "C2'" . U   F 3 10  ? 200.164 211.187 241.190 1.00 24.00  ? 11  U   T "C2'" 1 
ATOM   9951  O  "O2'" . U   F 3 10  ? 199.273 211.849 240.320 1.00 24.84  ? 11  U   T "O2'" 1 
ATOM   9952  C  "C1'" . U   F 3 10  ? 201.204 210.446 240.352 1.00 23.49  ? 11  U   T "C1'" 1 
ATOM   9953  N  N1    . U   F 3 10  ? 201.712 209.228 241.010 1.00 23.37  ? 11  U   T N1    1 
ATOM   9954  C  C2    . U   F 3 10  ? 200.910 208.097 240.988 1.00 23.22  ? 11  U   T C2    1 
ATOM   9955  O  O2    . U   F 3 10  ? 199.812 208.072 240.454 1.00 23.48  ? 11  U   T O2    1 
ATOM   9956  N  N3    . U   F 3 10  ? 201.441 206.999 241.608 1.00 23.37  ? 11  U   T N3    1 
ATOM   9957  C  C4    . U   F 3 10  ? 202.666 206.910 242.233 1.00 23.92  ? 11  U   T C4    1 
ATOM   9958  O  O4    . U   F 3 10  ? 203.012 205.851 242.751 1.00 25.76  ? 11  U   T O4    1 
ATOM   9959  C  C5    . U   F 3 10  ? 203.435 208.120 242.218 1.00 22.89  ? 11  U   T C5    1 
ATOM   9960  C  C6    . U   F 3 10  ? 202.943 209.212 241.615 1.00 22.26  ? 11  U   T C6    1 
ATOM   9961  P  P     . U   F 3 11  ? 199.923 213.369 244.000 1.00 28.42  ? 12  U   T P     1 
ATOM   9962  O  OP1   . U   F 3 11  ? 199.495 214.768 244.279 1.00 30.31  ? 12  U   T OP1   1 
ATOM   9963  O  OP2   . U   F 3 11  ? 201.029 212.787 244.804 1.00 25.93  ? 12  U   T OP2   1 
ATOM   9964  O  "O5'" . U   F 3 11  ? 198.680 212.369 244.116 1.00 34.13  ? 12  U   T "O5'" 1 
ATOM   9965  C  "C5'" . U   F 3 11  ? 197.454 212.668 243.402 1.00 39.49  ? 12  U   T "C5'" 1 
ATOM   9966  C  "C4'" . U   F 3 11  ? 196.613 211.420 243.280 1.00 44.97  ? 12  U   T "C4'" 1 
ATOM   9967  O  "O4'" . U   F 3 11  ? 197.377 210.364 242.645 1.00 45.16  ? 12  U   T "O4'" 1 
ATOM   9968  C  "C3'" . U   F 3 11  ? 196.134 210.794 244.595 1.00 50.40  ? 12  U   T "C3'" 1 
ATOM   9969  O  "O3'" . U   F 3 11  ? 194.964 211.430 245.087 1.00 59.78  ? 12  U   T "O3'" 1 
ATOM   9970  C  "C2'" . U   F 3 11  ? 195.848 209.358 244.151 1.00 50.49  ? 12  U   T "C2'" 1 
ATOM   9971  O  "O2'" . U   F 3 11  ? 194.618 209.235 243.468 1.00 51.32  ? 12  U   T "O2'" 1 
ATOM   9972  C  "C1'" . U   F 3 11  ? 196.988 209.108 243.162 1.00 46.48  ? 12  U   T "C1'" 1 
ATOM   9973  N  N1    . U   F 3 11  ? 198.160 208.458 243.786 1.00 42.63  ? 12  U   T N1    1 
ATOM   9974  C  C2    . U   F 3 11  ? 198.098 207.090 243.982 1.00 40.76  ? 12  U   T C2    1 
ATOM   9975  O  O2    . U   F 3 11  ? 197.126 206.422 243.663 1.00 43.14  ? 12  U   T O2    1 
ATOM   9976  N  N3    . U   F 3 11  ? 199.207 206.530 244.562 1.00 38.50  ? 12  U   T N3    1 
ATOM   9977  C  C4    . U   F 3 11  ? 200.356 207.186 244.953 1.00 38.53  ? 12  U   T C4    1 
ATOM   9978  O  O4    . U   F 3 11  ? 201.279 206.548 245.458 1.00 37.97  ? 12  U   T O4    1 
ATOM   9979  C  C5    . U   F 3 11  ? 200.344 208.602 244.720 1.00 39.00  ? 12  U   T C5    1 
ATOM   9980  C  C6    . U   F 3 11  ? 199.271 209.176 244.155 1.00 39.83  ? 12  U   T C6    1 
ATOM   9981  P  P     . U   F 3 12  ? 194.607 211.370 246.650 1.00 73.58  ? 13  U   T P     1 
ATOM   9982  O  OP1   . U   F 3 12  ? 193.464 212.289 246.914 1.00 77.94  ? 13  U   T OP1   1 
ATOM   9983  O  OP2   . U   F 3 12  ? 195.865 211.550 247.429 1.00 72.68  ? 13  U   T OP2   1 
ATOM   9984  O  "O5'" . U   F 3 12  ? 194.146 209.854 246.882 1.00 78.63  ? 13  U   T "O5'" 1 
ATOM   9985  C  "C5'" . U   F 3 12  ? 192.928 209.381 246.253 1.00 82.35  ? 13  U   T "C5'" 1 
ATOM   9986  C  "C4'" . U   F 3 12  ? 192.842 207.878 246.364 1.00 85.50  ? 13  U   T "C4'" 1 
ATOM   9987  O  "O4'" . U   F 3 12  ? 193.992 207.261 245.728 1.00 83.53  ? 13  U   T "O4'" 1 
ATOM   9988  C  "C3'" . U   F 3 12  ? 192.858 207.310 247.788 1.00 91.39  ? 13  U   T "C3'" 1 
ATOM   9989  O  "O3'" . U   F 3 12  ? 191.580 207.355 248.402 1.00 101.31 ? 13  U   T "O3'" 1 
ATOM   9990  C  "C2'" . U   F 3 12  ? 193.325 205.875 247.533 1.00 89.71  ? 13  U   T "C2'" 1 
ATOM   9991  O  "O2'" . U   F 3 12  ? 192.293 205.047 247.042 1.00 90.90  ? 13  U   T "O2'" 1 
ATOM   9992  C  "C1'" . U   F 3 12  ? 194.363 206.091 246.431 1.00 83.70  ? 13  U   T "C1'" 1 
ATOM   9993  N  N1    . U   F 3 12  ? 195.736 206.258 246.958 1.00 74.73  ? 13  U   T N1    1 
ATOM   9994  C  C2    . U   F 3 12  ? 196.434 205.111 247.294 1.00 69.68  ? 13  U   T C2    1 
ATOM   9995  O  O2    . U   F 3 12  ? 195.966 203.988 247.171 1.00 73.70  ? 13  U   T O2    1 
ATOM   9996  N  N3    . U   F 3 12  ? 197.700 205.322 247.776 1.00 63.67  ? 13  U   T N3    1 
ATOM   9997  C  C4    . U   F 3 12  ? 198.332 206.535 247.952 1.00 60.26  ? 13  U   T C4    1 
ATOM   9998  O  O4    . U   F 3 12  ? 199.479 206.563 248.397 1.00 57.68  ? 13  U   T O4    1 
ATOM   9999  C  C5    . U   F 3 12  ? 197.544 207.675 247.586 1.00 66.00  ? 13  U   T C5    1 
ATOM   10000 C  C6    . U   F 3 12  ? 196.302 207.501 247.113 1.00 71.70  ? 13  U   T C6    1 
ATOM   10001 P  P     . A   F 3 13  ? 191.456 207.648 249.976 1.00 111.62 ? 14  A   T P     1 
ATOM   10002 O  OP1   . A   F 3 13  ? 190.024 207.881 250.314 1.00 115.21 ? 14  A   T OP1   1 
ATOM   10003 O  OP2   . A   F 3 13  ? 192.450 208.703 250.323 1.00 108.54 ? 14  A   T OP2   1 
ATOM   10004 O  "O5'" . A   F 3 13  ? 191.951 206.284 250.650 1.00 112.50 ? 14  A   T "O5'" 1 
ATOM   10005 C  "C5'" . A   F 3 13  ? 191.204 205.066 250.405 1.00 115.00 ? 14  A   T "C5'" 1 
ATOM   10006 C  "C4'" . A   F 3 13  ? 192.006 203.865 250.843 1.00 115.74 ? 14  A   T "C4'" 1 
ATOM   10007 O  "O4'" . A   F 3 13  ? 193.204 203.741 250.035 1.00 111.34 ? 14  A   T "O4'" 1 
ATOM   10008 C  "C3'" . A   F 3 13  ? 192.535 203.895 252.279 1.00 119.71 ? 14  A   T "C3'" 1 
ATOM   10009 O  "O3'" . A   F 3 13  ? 191.549 203.508 253.219 1.00 133.95 ? 14  A   T "O3'" 1 
ATOM   10010 C  "C2'" . A   F 3 13  ? 193.690 202.898 252.191 1.00 114.85 ? 14  A   T "C2'" 1 
ATOM   10011 O  "O2'" . A   F 3 13  ? 193.257 201.556 252.219 1.00 115.34 ? 14  A   T "O2'" 1 
ATOM   10012 C  "C1'" . A   F 3 13  ? 194.266 203.233 250.817 1.00 107.80 ? 14  A   T "C1'" 1 
ATOM   10013 N  N9    . A   F 3 13  ? 195.335 204.224 250.871 1.00 93.66  ? 14  A   T N9    1 
ATOM   10014 C  C8    . A   F 3 13  ? 195.263 205.554 250.537 1.00 87.78  ? 14  A   T C8    1 
ATOM   10015 N  N7    . A   F 3 13  ? 196.391 206.197 250.701 1.00 85.34  ? 14  A   T N7    1 
ATOM   10016 C  C5    . A   F 3 13  ? 197.261 205.231 251.180 1.00 82.35  ? 14  A   T C5    1 
ATOM   10017 C  C6    . A   F 3 13  ? 198.617 205.284 251.548 1.00 77.02  ? 14  A   T C6    1 
ATOM   10018 N  N6    . A   F 3 13  ? 199.345 206.391 251.490 1.00 75.04  ? 14  A   T N6    1 
ATOM   10019 N  N1    . A   F 3 13  ? 199.193 204.139 251.985 1.00 79.27  ? 14  A   T N1    1 
ATOM   10020 C  C2    . A   F 3 13  ? 198.446 203.028 252.040 1.00 81.28  ? 14  A   T C2    1 
ATOM   10021 N  N3    . A   F 3 13  ? 197.166 202.858 251.718 1.00 83.47  ? 14  A   T N3    1 
ATOM   10022 C  C4    . A   F 3 13  ? 196.624 204.010 251.290 1.00 85.39  ? 14  A   T C4    1 
ATOM   10023 P  P     . A   F 3 14  ? 191.323 204.389 254.541 1.00 147.70 ? 15  A   T P     1 
ATOM   10024 O  OP1   . A   F 3 14  ? 189.942 204.164 255.052 1.00 150.19 ? 15  A   T OP1   1 
ATOM   10025 O  OP2   . A   F 3 14  ? 191.755 205.783 254.235 1.00 146.45 ? 15  A   T OP2   1 
ATOM   10026 O  "O5'" . A   F 3 14  ? 192.370 203.786 255.589 1.00 155.79 ? 15  A   T "O5'" 1 
ATOM   10027 C  "C5'" . A   F 3 14  ? 192.311 202.375 255.911 1.00 161.02 ? 15  A   T "C5'" 1 
ATOM   10028 C  "C4'" . A   F 3 14  ? 193.688 201.873 256.279 1.00 163.37 ? 15  A   T "C4'" 1 
ATOM   10029 O  "O4'" . A   F 3 14  ? 194.602 202.100 255.176 1.00 160.14 ? 15  A   T "O4'" 1 
ATOM   10030 C  "C3'" . A   F 3 14  ? 194.369 202.546 257.475 1.00 164.56 ? 15  A   T "C3'" 1 
ATOM   10031 O  "O3'" . A   F 3 14  ? 193.923 201.984 258.702 1.00 164.45 ? 15  A   T "O3'" 1 
ATOM   10032 C  "C2'" . A   F 3 14  ? 195.840 202.241 257.181 1.00 162.01 ? 15  A   T "C2'" 1 
ATOM   10033 O  "O2'" . A   F 3 14  ? 196.206 200.927 257.542 1.00 161.54 ? 15  A   T "O2'" 1 
ATOM   10034 C  "C1'" . A   F 3 14  ? 195.890 202.408 255.664 1.00 157.18 ? 15  A   T "C1'" 1 
ATOM   10035 N  N9    . A   F 3 14  ? 196.256 203.757 255.242 1.00 147.39 ? 15  A   T N9    1 
ATOM   10036 C  C8    . A   F 3 14  ? 195.424 204.745 254.774 1.00 142.77 ? 15  A   T C8    1 
ATOM   10037 N  N7    . A   F 3 14  ? 196.047 205.859 254.479 1.00 139.11 ? 15  A   T N7    1 
ATOM   10038 C  C5    . A   F 3 14  ? 197.376 205.593 254.775 1.00 138.19 ? 15  A   T C5    1 
ATOM   10039 C  C6    . A   F 3 14  ? 198.543 206.377 254.678 1.00 136.17 ? 15  A   T C6    1 
ATOM   10040 N  N6    . A   F 3 14  ? 198.555 207.632 254.239 1.00 135.08 ? 15  A   T N6    1 
ATOM   10041 N  N1    . A   F 3 14  ? 199.713 205.805 255.056 1.00 135.10 ? 15  A   T N1    1 
ATOM   10042 C  C2    . A   F 3 14  ? 199.695 204.540 255.495 1.00 138.69 ? 15  A   T C2    1 
ATOM   10043 N  N3    . A   F 3 14  ? 198.662 203.711 255.629 1.00 140.97 ? 15  A   T N3    1 
ATOM   10044 C  C4    . A   F 3 14  ? 197.517 204.302 255.248 1.00 141.27 ? 15  A   T C4    1 
ATOM   10045 P  P     . A   F 3 18  ? 201.253 193.385 252.235 1.00 167.14 ? 19  A   T P     1 
ATOM   10046 O  OP1   . A   F 3 18  ? 202.311 192.823 253.174 1.00 165.03 ? 19  A   T OP1   1 
ATOM   10047 O  OP2   . A   F 3 18  ? 201.540 193.092 250.774 1.00 164.51 ? 19  A   T OP2   1 
ATOM   10048 O  "O5'" . A   F 3 18  ? 201.279 194.997 252.410 1.00 153.34 ? 19  A   T "O5'" 1 
ATOM   10049 C  "C5'" . A   F 3 18  ? 201.695 195.837 251.299 1.00 141.50 ? 19  A   T "C5'" 1 
ATOM   10050 C  "C4'" . A   F 3 18  ? 200.495 196.183 250.455 1.00 131.22 ? 19  A   T "C4'" 1 
ATOM   10051 O  "O4'" . A   F 3 18  ? 199.946 197.451 250.897 1.00 122.25 ? 19  A   T "O4'" 1 
ATOM   10052 C  "C3'" . A   F 3 18  ? 200.766 196.400 248.965 1.00 125.26 ? 19  A   T "C3'" 1 
ATOM   10053 O  "O3'" . A   F 3 18  ? 200.816 195.172 248.255 1.00 120.46 ? 19  A   T "O3'" 1 
ATOM   10054 C  "C2'" . A   F 3 18  ? 199.563 197.262 248.575 1.00 120.47 ? 19  A   T "C2'" 1 
ATOM   10055 O  "O2'" . A   F 3 18  ? 198.388 196.502 248.404 1.00 121.51 ? 19  A   T "O2'" 1 
ATOM   10056 C  "C1'" . A   F 3 18  ? 199.428 198.167 249.796 1.00 112.82 ? 19  A   T "C1'" 1 
ATOM   10057 N  N9    . A   F 3 18  ? 200.141 199.433 249.660 1.00 95.74  ? 19  A   T N9    1 
ATOM   10058 C  C8    . A   F 3 18  ? 201.450 199.703 249.976 1.00 91.36  ? 19  A   T C8    1 
ATOM   10059 N  N7    . A   F 3 18  ? 201.800 200.943 249.737 1.00 87.37  ? 19  A   T N7    1 
ATOM   10060 C  C5    . A   F 3 18  ? 200.652 201.530 249.227 1.00 80.29  ? 19  A   T C5    1 
ATOM   10061 C  C6    . A   F 3 18  ? 200.370 202.836 248.781 1.00 73.50  ? 19  A   T C6    1 
ATOM   10062 N  N6    . A   F 3 18  ? 201.256 203.829 248.774 1.00 69.13  ? 19  A   T N6    1 
ATOM   10063 N  N1    . A   F 3 18  ? 199.117 203.082 248.332 1.00 70.26  ? 19  A   T N1    1 
ATOM   10064 C  C2    . A   F 3 18  ? 198.223 202.087 248.338 1.00 72.21  ? 19  A   T C2    1 
ATOM   10065 N  N3    . A   F 3 18  ? 198.373 200.827 248.735 1.00 79.42  ? 19  A   T N3    1 
ATOM   10066 C  C4    . A   F 3 18  ? 199.624 200.608 249.175 1.00 83.54  ? 19  A   T C4    1 
ATOM   10067 P  P     . A   F 3 19  ? 200.960 195.162 246.655 1.00 115.37 ? 20  A   T P     1 
ATOM   10068 O  OP1   . A   F 3 19  ? 201.631 193.905 246.219 1.00 113.13 ? 20  A   T OP1   1 
ATOM   10069 O  OP2   . A   F 3 19  ? 201.557 196.462 246.234 1.00 118.76 ? 20  A   T OP2   1 
ATOM   10070 O  "O5'" . A   F 3 19  ? 199.430 195.116 246.189 1.00 97.37  ? 20  A   T "O5'" 1 
ATOM   10071 C  "C5'" . A   F 3 19  ? 199.121 195.370 244.799 1.00 85.74  ? 20  A   T "C5'" 1 
ATOM   10072 C  "C4'" . A   F 3 19  ? 197.908 196.259 244.704 1.00 78.40  ? 20  A   T "C4'" 1 
ATOM   10073 O  "O4'" . A   F 3 19  ? 197.950 197.274 245.741 1.00 75.27  ? 20  A   T "O4'" 1 
ATOM   10074 C  "C3'" . A   F 3 19  ? 197.795 197.056 243.404 1.00 73.64  ? 20  A   T "C3'" 1 
ATOM   10075 O  "O3'" . A   F 3 19  ? 197.186 196.297 242.375 1.00 71.80  ? 20  A   T "O3'" 1 
ATOM   10076 C  "C2'" . A   F 3 19  ? 196.937 198.243 243.840 1.00 72.37  ? 20  A   T "C2'" 1 
ATOM   10077 O  "O2'" . A   F 3 19  ? 195.564 197.929 243.900 1.00 73.32  ? 20  A   T "O2'" 1 
ATOM   10078 C  "C1'" . A   F 3 19  ? 197.472 198.507 245.245 1.00 69.50  ? 20  A   T "C1'" 1 
ATOM   10079 N  N9    . A   F 3 19  ? 198.561 199.480 245.293 1.00 64.43  ? 20  A   T N9    1 
ATOM   10080 C  C8    . A   F 3 19  ? 199.883 199.216 245.554 1.00 62.16  ? 20  A   T C8    1 
ATOM   10081 N  N7    . A   F 3 19  ? 200.643 200.281 245.544 1.00 59.21  ? 20  A   T N7    1 
ATOM   10082 C  C5    . A   F 3 19  ? 199.767 201.318 245.264 1.00 54.95  ? 20  A   T C5    1 
ATOM   10083 C  C6    . A   F 3 19  ? 199.964 202.703 245.122 1.00 50.72  ? 20  A   T C6    1 
ATOM   10084 N  N6    . A   F 3 19  ? 201.151 203.292 245.248 1.00 50.01  ? 20  A   T N6    1 
ATOM   10085 N  N1    . A   F 3 19  ? 198.878 203.464 244.843 1.00 50.39  ? 20  A   T N1    1 
ATOM   10086 C  C2    . A   F 3 19  ? 197.689 202.860 244.717 1.00 53.89  ? 20  A   T C2    1 
ATOM   10087 N  N3    . A   F 3 19  ? 197.386 201.569 244.830 1.00 56.51  ? 20  A   T N3    1 
ATOM   10088 C  C4    . A   F 3 19  ? 198.480 200.839 245.107 1.00 56.96  ? 20  A   T C4    1 
ATOM   10089 P  P     . A   F 3 20  ? 197.838 196.273 240.911 1.00 70.37  ? 21  A   T P     1 
ATOM   10090 O  OP1   . A   F 3 20  ? 197.378 195.060 240.177 1.00 76.36  ? 21  A   T OP1   1 
ATOM   10091 O  OP2   . A   F 3 20  ? 199.300 196.523 241.042 1.00 71.37  ? 21  A   T OP2   1 
ATOM   10092 O  "O5'" . A   F 3 20  ? 197.203 197.556 240.202 1.00 64.37  ? 21  A   T "O5'" 1 
ATOM   10093 C  "C5'" . A   F 3 20  ? 195.764 197.697 240.169 1.00 59.48  ? 21  A   T "C5'" 1 
ATOM   10094 C  "C4'" . A   F 3 20  ? 195.398 199.133 239.886 1.00 56.22  ? 21  A   T "C4'" 1 
ATOM   10095 O  "O4'" . A   F 3 20  ? 195.677 199.954 241.051 1.00 56.17  ? 21  A   T "O4'" 1 
ATOM   10096 C  "C3'" . A   F 3 20  ? 196.183 199.815 238.766 1.00 55.31  ? 21  A   T "C3'" 1 
ATOM   10097 O  "O3'" . A   F 3 20  ? 195.679 199.497 237.480 1.00 55.08  ? 21  A   T "O3'" 1 
ATOM   10098 C  "C2'" . A   F 3 20  ? 195.983 201.286 239.127 1.00 52.28  ? 21  A   T "C2'" 1 
ATOM   10099 O  "O2'" . A   F 3 20  ? 194.707 201.768 238.769 1.00 53.23  ? 21  A   T "O2'" 1 
ATOM   10100 C  "C1'" . A   F 3 20  ? 196.113 201.235 240.646 1.00 50.22  ? 21  A   T "C1'" 1 
ATOM   10101 N  N9    . A   F 3 20  ? 197.483 201.442 241.105 1.00 45.59  ? 21  A   T N9    1 
ATOM   10102 C  C8    . A   F 3 20  ? 198.385 200.494 241.522 1.00 44.27  ? 21  A   T C8    1 
ATOM   10103 N  N7    . A   F 3 20  ? 199.545 200.992 241.871 1.00 42.71  ? 21  A   T N7    1 
ATOM   10104 C  C5    . A   F 3 20  ? 199.404 202.357 241.663 1.00 41.05  ? 21  A   T C5    1 
ATOM   10105 C  C6    . A   F 3 20  ? 200.285 203.439 241.848 1.00 35.74  ? 21  A   T C6    1 
ATOM   10106 N  N6    . A   F 3 20  ? 201.530 203.308 242.297 1.00 32.33  ? 21  A   T N6    1 
ATOM   10107 N  N1    . A   F 3 20  ? 199.823 204.673 241.545 1.00 35.06  ? 21  A   T N1    1 
ATOM   10108 C  C2    . A   F 3 20  ? 198.571 204.801 241.091 1.00 36.80  ? 21  A   T C2    1 
ATOM   10109 N  N3    . A   F 3 20  ? 197.656 203.862 240.881 1.00 39.82  ? 21  A   T N3    1 
ATOM   10110 C  C4    . A   F 3 20  ? 198.139 202.646 241.188 1.00 42.14  ? 21  A   T C4    1 
ATOM   10111 P  P     . C   F 3 21  ? 196.698 199.289 236.259 1.00 58.83  ? 22  C   T P     1 
ATOM   10112 O  OP1   . C   F 3 21  ? 195.954 198.750 235.084 1.00 63.30  ? 22  C   T OP1   1 
ATOM   10113 O  OP2   . C   F 3 21  ? 197.889 198.544 236.757 1.00 57.14  ? 22  C   T OP2   1 
ATOM   10114 O  "O5'" . C   F 3 21  ? 197.180 200.778 235.928 1.00 53.89  ? 22  C   T "O5'" 1 
ATOM   10115 C  "C5'" . C   F 3 21  ? 196.178 201.764 235.587 1.00 51.42  ? 22  C   T "C5'" 1 
ATOM   10116 C  "C4'" . C   F 3 21  ? 196.755 203.152 235.704 1.00 48.60  ? 22  C   T "C4'" 1 
ATOM   10117 O  "O4'" . C   F 3 21  ? 197.226 203.397 237.053 1.00 45.89  ? 22  C   T "O4'" 1 
ATOM   10118 C  "C3'" . C   F 3 21  ? 197.987 203.440 234.845 1.00 46.92  ? 22  C   T "C3'" 1 
ATOM   10119 O  "O3'" . C   F 3 21  ? 197.646 203.704 233.497 1.00 48.43  ? 22  C   T "O3'" 1 
ATOM   10120 C  "C2'" . C   F 3 21  ? 198.555 204.669 235.556 1.00 43.29  ? 22  C   T "C2'" 1 
ATOM   10121 O  "O2'" . C   F 3 21  ? 197.846 205.845 235.237 1.00 45.12  ? 22  C   T "O2'" 1 
ATOM   10122 C  "C1'" . C   F 3 21  ? 198.296 204.319 237.024 1.00 40.90  ? 22  C   T "C1'" 1 
ATOM   10123 N  N1    . C   F 3 21  ? 199.481 203.712 237.685 1.00 34.63  ? 22  C   T N1    1 
ATOM   10124 C  C2    . C   F 3 21  ? 200.492 204.570 238.134 1.00 32.77  ? 22  C   T C2    1 
ATOM   10125 O  O2    . C   F 3 21  ? 200.363 205.791 237.958 1.00 30.49  ? 22  C   T O2    1 
ATOM   10126 N  N3    . C   F 3 21  ? 201.588 204.046 238.734 1.00 28.65  ? 22  C   T N3    1 
ATOM   10127 C  C4    . C   F 3 21  ? 201.694 202.727 238.905 1.00 31.70  ? 22  C   T C4    1 
ATOM   10128 N  N4    . C   F 3 21  ? 202.788 202.280 239.502 1.00 30.35  ? 22  C   T N4    1 
ATOM   10129 C  C5    . C   F 3 21  ? 200.675 201.836 238.455 1.00 32.59  ? 22  C   T C5    1 
ATOM   10130 C  C6    . C   F 3 21  ? 199.594 202.365 237.858 1.00 32.77  ? 22  C   T C6    1 
ATOM   10131 P  P     . A   F 3 22  ? 198.728 203.407 232.351 1.00 51.50  ? 23  A   T P     1 
ATOM   10132 O  OP1   . A   F 3 22  ? 198.083 203.541 231.011 1.00 54.71  ? 23  A   T OP1   1 
ATOM   10133 O  OP2   . A   F 3 22  ? 199.442 202.139 232.678 1.00 47.43  ? 23  A   T OP2   1 
ATOM   10134 O  "O5'" . A   F 3 22  ? 199.732 204.637 232.547 1.00 47.22  ? 23  A   T "O5'" 1 
ATOM   10135 C  "C5'" . A   F 3 22  ? 201.142 204.368 232.507 1.00 40.59  ? 23  A   T "C5'" 1 
ATOM   10136 C  "C4'" . A   F 3 22  ? 201.898 205.436 233.260 1.00 36.33  ? 23  A   T "C4'" 1 
ATOM   10137 O  "O4'" . A   F 3 22  ? 201.819 205.198 234.691 1.00 33.23  ? 23  A   T "O4'" 1 
ATOM   10138 C  "C3'" . A   F 3 22  ? 203.400 205.444 232.982 1.00 31.13  ? 23  A   T "C3'" 1 
ATOM   10139 O  "O3'" . A   F 3 22  ? 203.718 206.134 231.790 1.00 28.44  ? 23  A   T "O3'" 1 
ATOM   10140 C  "C2'" . A   F 3 22  ? 203.943 206.108 234.245 1.00 31.06  ? 23  A   T "C2'" 1 
ATOM   10141 O  "O2'" . A   F 3 22  ? 203.779 207.505 234.230 1.00 29.38  ? 23  A   T "O2'" 1 
ATOM   10142 C  "C1'" . A   F 3 22  ? 203.064 205.459 235.308 1.00 30.71  ? 23  A   T "C1'" 1 
ATOM   10143 N  N9    . A   F 3 22  ? 203.613 204.207 235.811 1.00 29.42  ? 23  A   T N9    1 
ATOM   10144 C  C8    . A   F 3 22  ? 203.029 202.966 235.740 1.00 29.78  ? 23  A   T C8    1 
ATOM   10145 N  N7    . A   F 3 22  ? 203.758 202.014 236.261 1.00 31.26  ? 23  A   T N7    1 
ATOM   10146 C  C5    . A   F 3 22  ? 204.897 202.664 236.707 1.00 28.42  ? 23  A   T C5    1 
ATOM   10147 C  C6    . A   F 3 22  ? 206.051 202.197 237.359 1.00 27.80  ? 23  A   T C6    1 
ATOM   10148 N  N6    . A   F 3 22  ? 206.243 200.923 237.684 1.00 29.18  ? 23  A   T N6    1 
ATOM   10149 N  N1    . A   F 3 22  ? 207.007 203.106 237.665 1.00 26.82  ? 23  A   T N1    1 
ATOM   10150 C  C2    . A   F 3 22  ? 206.795 204.387 237.337 1.00 24.98  ? 23  A   T C2    1 
ATOM   10151 N  N3    . A   F 3 22  ? 205.751 204.940 236.732 1.00 26.56  ? 23  A   T N3    1 
ATOM   10152 C  C4    . A   F 3 22  ? 204.824 204.015 236.434 1.00 28.73  ? 23  A   T C4    1 
ATOM   10153 P  P     . U   F 3 23  ? 204.646 205.413 230.703 1.00 24.61  ? 24  U   T P     1 
ATOM   10154 O  OP1   . U   F 3 23  ? 204.641 206.195 229.434 1.00 27.88  ? 24  U   T OP1   1 
ATOM   10155 O  OP2   . U   F 3 23  ? 204.330 203.960 230.657 1.00 27.24  ? 24  U   T OP2   1 
ATOM   10156 O  "O5'" . U   F 3 23  ? 206.096 205.507 231.354 1.00 22.45  ? 24  U   T "O5'" 1 
ATOM   10157 C  "C5'" . U   F 3 23  ? 206.558 206.761 231.906 1.00 20.23  ? 24  U   T "C5'" 1 
ATOM   10158 C  "C4'" . U   F 3 23  ? 207.886 206.546 232.587 1.00 19.29  ? 24  U   T "C4'" 1 
ATOM   10159 O  "O4'" . U   F 3 23  ? 207.724 205.862 233.852 1.00 19.13  ? 24  U   T "O4'" 1 
ATOM   10160 C  "C3'" . U   F 3 23  ? 208.864 205.654 231.830 1.00 18.17  ? 24  U   T "C3'" 1 
ATOM   10161 O  "O3'" . U   F 3 23  ? 209.520 206.344 230.789 1.00 18.86  ? 24  U   T "O3'" 1 
ATOM   10162 C  "C2'" . U   F 3 23  ? 209.826 205.250 232.945 1.00 19.29  ? 24  U   T "C2'" 1 
ATOM   10163 O  "O2'" . U   F 3 23  ? 210.748 206.267 233.284 1.00 19.04  ? 24  U   T "O2'" 1 
ATOM   10164 C  "C1'" . U   F 3 23  ? 208.852 205.049 234.107 1.00 19.87  ? 24  U   T "C1'" 1 
ATOM   10165 N  N1    . U   F 3 23  ? 208.410 203.646 234.252 1.00 19.64  ? 24  U   T N1    1 
ATOM   10166 C  C2    . U   F 3 23  ? 209.287 202.762 234.843 1.00 20.50  ? 24  U   T C2    1 
ATOM   10167 O  O2    . U   F 3 23  ? 210.396 203.091 235.236 1.00 20.39  ? 24  U   T O2    1 
ATOM   10168 N  N3    . U   F 3 23  ? 208.818 201.478 234.960 1.00 20.45  ? 24  U   T N3    1 
ATOM   10169 C  C4    . U   F 3 23  ? 207.593 201.001 234.549 1.00 20.57  ? 24  U   T C4    1 
ATOM   10170 O  O4    . U   F 3 23  ? 207.318 199.816 234.726 1.00 21.04  ? 24  U   T O4    1 
ATOM   10171 C  C5    . U   F 3 23  ? 206.743 201.976 233.935 1.00 21.63  ? 24  U   T C5    1 
ATOM   10172 C  C6    . U   F 3 23  ? 207.172 203.239 233.819 1.00 21.08  ? 24  U   T C6    1 
ATOM   10173 P  P     . C   F 3 24  ? 209.813 205.595 229.412 1.00 16.60  ? 25  C   T P     1 
ATOM   10174 O  OP1   . C   F 3 24  ? 210.081 206.583 228.332 1.00 19.45  ? 25  C   T OP1   1 
ATOM   10175 O  OP2   . C   F 3 24  ? 208.765 204.572 229.166 1.00 18.89  ? 25  C   T OP2   1 
ATOM   10176 O  "O5'" . C   F 3 24  ? 211.160 204.822 229.748 1.00 16.07  ? 25  C   T "O5'" 1 
ATOM   10177 C  "C5'" . C   F 3 24  ? 212.309 205.540 230.217 1.00 15.74  ? 25  C   T "C5'" 1 
ATOM   10178 C  "C4'" . C   F 3 24  ? 213.393 204.559 230.575 1.00 15.47  ? 25  C   T "C4'" 1 
ATOM   10179 O  "O4'" . C   F 3 24  ? 213.070 203.863 231.811 1.00 16.36  ? 25  C   T "O4'" 1 
ATOM   10180 C  "C3'" . C   F 3 24  ? 213.611 203.423 229.574 1.00 15.94  ? 25  C   T "C3'" 1 
ATOM   10181 O  "O3'" . C   F 3 24  ? 214.387 203.805 228.455 1.00 16.09  ? 25  C   T "O3'" 1 
ATOM   10182 C  "C2'" . C   F 3 24  ? 214.328 202.393 230.447 1.00 15.70  ? 25  C   T "C2'" 1 
ATOM   10183 O  "O2'" . C   F 3 24  ? 215.678 202.712 230.678 1.00 15.68  ? 25  C   T "O2'" 1 
ATOM   10184 C  "C1'" . C   F 3 24  ? 213.543 202.528 231.751 1.00 15.82  ? 25  C   T "C1'" 1 
ATOM   10185 N  N1    . C   F 3 24  ? 212.385 201.598 231.804 1.00 15.89  ? 25  C   T N1    1 
ATOM   10186 C  C2    . C   F 3 24  ? 212.616 200.264 232.144 1.00 16.73  ? 25  C   T C2    1 
ATOM   10187 O  O2    . C   F 3 24  ? 213.775 199.898 232.368 1.00 17.71  ? 25  C   T O2    1 
ATOM   10188 N  N3    . C   F 3 24  ? 211.571 199.408 232.201 1.00 17.13  ? 25  C   T N3    1 
ATOM   10189 C  C4    . C   F 3 24  ? 210.333 199.837 231.950 1.00 16.38  ? 25  C   T C4    1 
ATOM   10190 N  N4    . C   F 3 24  ? 209.345 198.960 232.023 1.00 16.47  ? 25  C   T N4    1 
ATOM   10191 C  C5    . C   F 3 24  ? 210.076 201.192 231.600 1.00 16.72  ? 25  C   T C5    1 
ATOM   10192 C  C6    . C   F 3 24  ? 211.120 202.028 231.543 1.00 16.08  ? 25  C   T C6    1 
ATOM   10193 P  P     . A   F 3 25  ? 214.109 203.111 227.045 1.00 15.27  ? 26  A   T P     1 
ATOM   10194 O  OP1   . A   F 3 25  ? 214.770 203.872 225.949 1.00 17.84  ? 26  A   T OP1   1 
ATOM   10195 O  OP2   . A   F 3 25  ? 212.657 202.828 226.928 1.00 15.79  ? 26  A   T OP2   1 
ATOM   10196 O  "O5'" . A   F 3 25  ? 214.846 201.713 227.196 1.00 15.91  ? 26  A   T "O5'" 1 
ATOM   10197 C  "C5'" . A   F 3 25  ? 216.244 201.662 227.525 1.00 16.61  ? 26  A   T "C5'" 1 
ATOM   10198 C  "C4'" . A   F 3 25  ? 216.680 200.221 227.622 1.00 18.08  ? 26  A   T "C4'" 1 
ATOM   10199 O  "O4'" . A   F 3 25  ? 216.155 199.606 228.829 1.00 18.30  ? 26  A   T "O4'" 1 
ATOM   10200 C  "C3'" . A   F 3 25  ? 216.172 199.302 226.509 1.00 18.71  ? 26  A   T "C3'" 1 
ATOM   10201 O  "O3'" . A   F 3 25  ? 216.946 199.409 225.329 1.00 19.11  ? 26  A   T "O3'" 1 
ATOM   10202 C  "C2'" . A   F 3 25  ? 216.317 197.935 227.171 1.00 18.76  ? 26  A   T "C2'" 1 
ATOM   10203 O  "O2'" . A   F 3 25  ? 217.651 197.484 227.200 1.00 19.55  ? 26  A   T "O2'" 1 
ATOM   10204 C  "C1'" . A   F 3 25  ? 215.842 198.248 228.582 1.00 18.20  ? 26  A   T "C1'" 1 
ATOM   10205 N  N9    . A   F 3 25  ? 214.411 198.044 228.757 1.00 17.86  ? 26  A   T N9    1 
ATOM   10206 C  C8    . A   F 3 25  ? 213.427 198.998 228.795 1.00 18.01  ? 26  A   T C8    1 
ATOM   10207 N  N7    . A   F 3 25  ? 212.226 198.504 228.978 1.00 18.63  ? 26  A   T N7    1 
ATOM   10208 C  C5    . A   F 3 25  ? 212.429 197.136 229.063 1.00 19.00  ? 26  A   T C5    1 
ATOM   10209 C  C6    . A   F 3 25  ? 211.547 196.058 229.254 1.00 18.26  ? 26  A   T C6    1 
ATOM   10210 N  N6    . A   F 3 25  ? 210.235 196.193 229.396 1.00 17.98  ? 26  A   T N6    1 
ATOM   10211 N  N1    . A   F 3 25  ? 212.084 194.819 229.291 1.00 20.03  ? 26  A   T N1    1 
ATOM   10212 C  C2    . A   F 3 25  ? 213.404 194.682 229.145 1.00 19.16  ? 26  A   T C2    1 
ATOM   10213 N  N3    . A   F 3 25  ? 214.329 195.618 228.964 1.00 21.05  ? 26  A   T N3    1 
ATOM   10214 C  C4    . A   F 3 25  ? 213.772 196.841 228.928 1.00 20.02  ? 26  A   T C4    1 
ATOM   10215 P  P     . G   F 3 26  ? 216.235 199.249 223.906 1.00 19.93  ? 27  G   T P     1 
ATOM   10216 O  OP1   . G   F 3 26  ? 217.212 199.647 222.855 1.00 22.28  ? 27  G   T OP1   1 
ATOM   10217 O  OP2   . G   F 3 26  ? 214.922 199.945 223.947 1.00 21.29  ? 27  G   T OP2   1 
ATOM   10218 O  "O5'" . G   F 3 26  ? 215.931 197.679 223.836 1.00 23.25  ? 27  G   T "O5'" 1 
ATOM   10219 C  "C5'" . G   F 3 26  ? 217.044 196.751 223.838 1.00 24.72  ? 27  G   T "C5'" 1 
ATOM   10220 C  "C4'" . G   F 3 26  ? 216.542 195.339 224.029 1.00 26.16  ? 27  G   T "C4'" 1 
ATOM   10221 O  "O4'" . G   F 3 26  ? 215.852 195.217 225.297 1.00 25.16  ? 27  G   T "O4'" 1 
ATOM   10222 C  "C3'" . G   F 3 26  ? 215.505 194.842 223.019 1.00 27.14  ? 27  G   T "C3'" 1 
ATOM   10223 O  "O3'" . G   F 3 26  ? 216.093 194.433 221.800 1.00 30.55  ? 27  G   T "O3'" 1 
ATOM   10224 C  "C2'" . G   F 3 26  ? 214.910 193.663 223.789 1.00 27.44  ? 27  G   T "C2'" 1 
ATOM   10225 O  "O2'" . G   F 3 26  ? 215.728 192.514 223.764 1.00 29.35  ? 27  G   T "O2'" 1 
ATOM   10226 C  "C1'" . G   F 3 26  ? 214.847 194.229 225.204 1.00 24.89  ? 27  G   T "C1'" 1 
ATOM   10227 N  N9    . G   F 3 26  ? 213.554 194.822 225.516 1.00 23.49  ? 27  G   T N9    1 
ATOM   10228 C  C8    . G   F 3 26  ? 213.214 196.151 225.520 1.00 22.62  ? 27  G   T C8    1 
ATOM   10229 N  N7    . G   F 3 26  ? 211.962 196.364 225.842 1.00 23.17  ? 27  G   T N7    1 
ATOM   10230 C  C5    . G   F 3 26  ? 211.446 195.091 226.054 1.00 23.14  ? 27  G   T C5    1 
ATOM   10231 C  C6    . G   F 3 26  ? 210.142 194.685 226.420 1.00 23.02  ? 27  G   T C6    1 
ATOM   10232 O  O6    . G   F 3 26  ? 209.151 195.388 226.648 1.00 23.84  ? 27  G   T O6    1 
ATOM   10233 N  N1    . G   F 3 26  ? 210.052 193.303 226.526 1.00 24.28  ? 27  G   T N1    1 
ATOM   10234 C  C2    . G   F 3 26  ? 211.080 192.420 226.304 1.00 23.65  ? 27  G   T C2    1 
ATOM   10235 N  N2    . G   F 3 26  ? 210.803 191.119 226.454 1.00 24.83  ? 27  G   T N2    1 
ATOM   10236 N  N3    . G   F 3 26  ? 212.306 192.792 225.954 1.00 23.92  ? 27  G   T N3    1 
ATOM   10237 C  C4    . G   F 3 26  ? 212.415 194.137 225.851 1.00 23.32  ? 27  G   T C4    1 
ATOM   10238 P  P     . A   F 3 27  ? 215.378 194.785 220.410 1.00 34.10  ? 28  A   T P     1 
ATOM   10239 O  OP1   . A   F 3 27  ? 216.247 194.301 219.299 1.00 39.19  ? 28  A   T OP1   1 
ATOM   10240 O  OP2   . A   F 3 27  ? 214.977 196.218 220.429 1.00 33.74  ? 28  A   T OP2   1 
ATOM   10241 O  "O5'" . A   F 3 27  ? 214.047 193.902 220.466 1.00 36.25  ? 28  A   T "O5'" 1 
ATOM   10242 C  "C5'" . A   F 3 27  ? 214.157 192.468 220.647 1.00 38.48  ? 28  A   T "C5'" 1 
ATOM   10243 C  "C4'" . A   F 3 27  ? 212.795 191.824 220.555 1.00 41.26  ? 28  A   T "C4'" 1 
ATOM   10244 O  "O4'" . A   F 3 27  ? 211.970 192.192 221.699 1.00 39.97  ? 28  A   T "O4'" 1 
ATOM   10245 C  "C3'" . A   F 3 27  ? 211.968 192.198 219.315 1.00 43.76  ? 28  A   T "C3'" 1 
ATOM   10246 O  "O3'" . A   F 3 27  ? 211.237 191.072 218.856 1.00 48.33  ? 28  A   T "O3'" 1 
ATOM   10247 C  "C2'" . A   F 3 27  ? 210.993 193.243 219.859 1.00 42.16  ? 28  A   T "C2'" 1 
ATOM   10248 O  "O2'" . A   F 3 27  ? 209.810 193.391 219.101 1.00 43.33  ? 28  A   T "O2'" 1 
ATOM   10249 C  "C1'" . A   F 3 27  ? 210.718 192.627 221.228 1.00 41.53  ? 28  A   T "C1'" 1 
ATOM   10250 N  N9    . A   F 3 27  ? 210.098 193.552 222.169 1.00 35.95  ? 28  A   T N9    1 
ATOM   10251 C  C8    . A   F 3 27  ? 210.417 194.864 222.414 1.00 34.19  ? 28  A   T C8    1 
ATOM   10252 N  N7    . A   F 3 27  ? 209.607 195.443 223.267 1.00 33.39  ? 28  A   T N7    1 
ATOM   10253 C  C5    . A   F 3 27  ? 208.676 194.460 223.569 1.00 32.51  ? 28  A   T C5    1 
ATOM   10254 C  C6    . A   F 3 27  ? 207.549 194.439 224.408 1.00 32.69  ? 28  A   T C6    1 
ATOM   10255 N  N6    . A   F 3 27  ? 207.161 195.475 225.142 1.00 35.44  ? 28  A   T N6    1 
ATOM   10256 N  N1    . A   F 3 27  ? 206.844 193.285 224.488 1.00 31.24  ? 28  A   T N1    1 
ATOM   10257 C  C2    . A   F 3 27  ? 207.242 192.241 223.757 1.00 30.14  ? 28  A   T C2    1 
ATOM   10258 N  N3    . A   F 3 27  ? 208.276 192.144 222.933 1.00 32.79  ? 28  A   T N3    1 
ATOM   10259 C  C4    . A   F 3 27  ? 208.961 193.297 222.886 1.00 32.36  ? 28  A   T C4    1 
ATOM   10260 P  P     . U   F 3 28  ? 211.506 190.441 217.405 1.00 52.82  ? 29  U   T P     1 
ATOM   10261 O  OP1   . U   F 3 28  ? 210.635 189.235 217.293 1.00 53.43  ? 29  U   T OP1   1 
ATOM   10262 O  OP2   . U   F 3 28  ? 212.980 190.287 217.223 1.00 55.58  ? 29  U   T OP2   1 
ATOM   10263 O  "O5'" . U   F 3 28  ? 211.002 191.561 216.376 1.00 44.09  ? 29  U   T "O5'" 1 
ATOM   10264 C  "C5'" . U   F 3 28  ? 209.623 191.992 216.466 1.00 39.79  ? 29  U   T "C5'" 1 
ATOM   10265 C  "C4'" . U   F 3 28  ? 208.979 192.037 215.103 1.00 38.49  ? 29  U   T "C4'" 1 
ATOM   10266 O  "O4'" . U   F 3 28  ? 209.583 193.097 214.317 1.00 37.70  ? 29  U   T "O4'" 1 
ATOM   10267 C  "C3'" . U   F 3 28  ? 209.076 190.762 214.254 1.00 36.78  ? 29  U   T "C3'" 1 
ATOM   10268 O  "O3'" . U   F 3 28  ? 207.851 190.553 213.575 1.00 35.98  ? 29  U   T "O3'" 1 
ATOM   10269 C  "C2'" . U   F 3 28  ? 210.212 191.083 213.280 1.00 36.27  ? 29  U   T "C2'" 1 
ATOM   10270 O  "O2'" . U   F 3 28  ? 210.103 190.382 212.057 1.00 36.52  ? 29  U   T "O2'" 1 
ATOM   10271 C  "C1'" . U   F 3 28  ? 209.987 192.582 213.073 1.00 37.50  ? 29  U   T "C1'" 1 
ATOM   10272 N  N1    . U   F 3 28  ? 211.205 193.289 212.645 1.00 38.71  ? 29  U   T N1    1 
ATOM   10273 C  C2    . U   F 3 28  ? 211.124 194.058 211.498 1.00 40.16  ? 29  U   T C2    1 
ATOM   10274 O  O2    . U   F 3 28  ? 210.092 194.184 210.853 1.00 42.15  ? 29  U   T O2    1 
ATOM   10275 N  N3    . U   F 3 28  ? 212.296 194.663 211.124 1.00 39.70  ? 29  U   T N3    1 
ATOM   10276 C  C4    . U   F 3 28  ? 213.512 194.578 211.766 1.00 39.21  ? 29  U   T C4    1 
ATOM   10277 O  O4    . U   F 3 28  ? 214.475 195.193 211.310 1.00 42.99  ? 29  U   T O4    1 
ATOM   10278 C  C5    . U   F 3 28  ? 213.512 193.771 212.952 1.00 39.99  ? 29  U   T C5    1 
ATOM   10279 C  C6    . U   F 3 28  ? 212.380 193.169 213.346 1.00 40.02  ? 29  U   T C6    1 
ATOM   10280 P  P     . U   F 3 29  ? 206.798 189.484 214.137 1.00 36.41  ? 30  U   T P     1 
ATOM   10281 O  OP1   . U   F 3 29  ? 207.471 188.164 214.314 1.00 39.18  ? 30  U   T OP1   1 
ATOM   10282 O  OP2   . U   F 3 29  ? 205.556 189.559 213.312 1.00 39.05  ? 30  U   T OP2   1 
ATOM   10283 O  "O5'" . U   F 3 29  ? 206.498 190.068 215.593 1.00 32.85  ? 30  U   T "O5'" 1 
ATOM   10284 C  "C5'" . U   F 3 29  ? 206.198 189.149 216.673 1.00 28.18  ? 30  U   T "C5'" 1 
ATOM   10285 C  "C4'" . U   F 3 29  ? 204.914 189.547 217.357 1.00 27.04  ? 30  U   T "C4'" 1 
ATOM   10286 O  "O4'" . U   F 3 29  ? 205.100 190.797 218.080 1.00 24.69  ? 30  U   T "O4'" 1 
ATOM   10287 C  "C3'" . U   F 3 29  ? 203.700 189.767 216.441 1.00 25.97  ? 30  U   T "C3'" 1 
ATOM   10288 O  "O3'" . U   F 3 29  ? 202.528 189.284 217.073 1.00 29.43  ? 30  U   T "O3'" 1 
ATOM   10289 C  "C2'" . U   F 3 29  ? 203.651 191.288 216.288 1.00 24.15  ? 30  U   T "C2'" 1 
ATOM   10290 O  "O2'" . U   F 3 29  ? 202.354 191.783 216.024 1.00 22.52  ? 30  U   T "O2'" 1 
ATOM   10291 C  "C1'" . U   F 3 29  ? 204.110 191.721 217.685 1.00 23.38  ? 30  U   T "C1'" 1 
ATOM   10292 N  N1    . U   F 3 29  ? 204.692 193.074 217.691 1.00 21.15  ? 30  U   T N1    1 
ATOM   10293 C  C2    . U   F 3 29  ? 203.925 194.097 218.211 1.00 19.51  ? 30  U   T C2    1 
ATOM   10294 O  O2    . U   F 3 29  ? 202.813 193.920 218.674 1.00 20.17  ? 30  U   T O2    1 
ATOM   10295 N  N3    . U   F 3 29  ? 204.506 195.334 218.176 1.00 20.33  ? 30  U   T N3    1 
ATOM   10296 C  C4    . U   F 3 29  ? 205.751 195.646 217.676 1.00 21.22  ? 30  U   T C4    1 
ATOM   10297 O  O4    . U   F 3 29  ? 206.137 196.813 217.715 1.00 23.43  ? 30  U   T O4    1 
ATOM   10298 C  C5    . U   F 3 29  ? 206.488 194.533 217.156 1.00 20.96  ? 30  U   T C5    1 
ATOM   10299 C  C6    . U   F 3 29  ? 205.941 193.310 217.177 1.00 20.47  ? 30  U   T C6    1 
ATOM   10300 P  P     . G   F 3 30  ? 201.720 188.034 216.468 1.00 29.67  ? 31  G   T P     1 
ATOM   10301 O  OP1   . G   F 3 30  ? 200.500 187.802 217.298 1.00 31.53  ? 31  G   T OP1   1 
ATOM   10302 O  OP2   . G   F 3 30  ? 202.687 186.922 216.265 1.00 31.60  ? 31  G   T OP2   1 
ATOM   10303 O  "O5'" . G   F 3 30  ? 201.276 188.554 215.027 1.00 29.63  ? 31  G   T "O5'" 1 
ATOM   10304 C  "C5'" . G   F 3 30  ? 200.203 189.524 214.916 1.00 30.45  ? 31  G   T "C5'" 1 
ATOM   10305 C  "C4'" . G   F 3 30  ? 199.202 189.093 213.873 1.00 31.71  ? 31  G   T "C4'" 1 
ATOM   10306 O  "O4'" . G   F 3 30  ? 199.715 189.395 212.545 1.00 32.71  ? 31  G   T "O4'" 1 
ATOM   10307 C  "C3'" . G   F 3 30  ? 198.849 187.600 213.846 1.00 31.93  ? 31  G   T "C3'" 1 
ATOM   10308 O  "O3'" . G   F 3 30  ? 197.487 187.442 213.488 1.00 35.35  ? 31  G   T "O3'" 1 
ATOM   10309 C  "C2'" . G   F 3 30  ? 199.755 187.059 212.740 1.00 31.35  ? 31  G   T "C2'" 1 
ATOM   10310 O  "O2'" . G   F 3 30  ? 199.276 185.871 212.147 1.00 32.88  ? 31  G   T "O2'" 1 
ATOM   10311 C  "C1'" . G   F 3 30  ? 199.730 188.228 211.757 1.00 31.45  ? 31  G   T "C1'" 1 
ATOM   10312 N  N9    . G   F 3 30  ? 200.887 188.292 210.877 1.00 30.91  ? 31  G   T N9    1 
ATOM   10313 C  C8    . G   F 3 30  ? 202.187 188.523 211.248 1.00 31.99  ? 31  G   T C8    1 
ATOM   10314 N  N7    . G   F 3 30  ? 203.022 188.535 210.239 1.00 31.55  ? 31  G   T N7    1 
ATOM   10315 C  C5    . G   F 3 30  ? 202.216 188.285 209.136 1.00 31.11  ? 31  G   T C5    1 
ATOM   10316 C  C6    . G   F 3 30  ? 202.562 188.165 207.771 1.00 30.56  ? 31  G   T C6    1 
ATOM   10317 O  O6    . G   F 3 30  ? 203.685 188.262 207.259 1.00 31.30  ? 31  G   T O6    1 
ATOM   10318 N  N1    . G   F 3 30  ? 201.442 187.890 206.984 1.00 30.95  ? 31  G   T N1    1 
ATOM   10319 C  C2    . G   F 3 30  ? 200.156 187.769 207.451 1.00 31.55  ? 31  G   T C2    1 
ATOM   10320 N  N2    . G   F 3 30  ? 199.204 187.527 206.540 1.00 32.37  ? 31  G   T N2    1 
ATOM   10321 N  N3    . G   F 3 30  ? 199.822 187.896 208.734 1.00 30.53  ? 31  G   T N3    1 
ATOM   10322 C  C4    . G   F 3 30  ? 200.900 188.143 209.514 1.00 30.39  ? 31  G   T C4    1 
ATOM   10323 P  P     . U   F 3 31  ? 196.350 187.264 214.608 1.00 37.69  ? 32  U   T P     1 
ATOM   10324 O  OP1   . U   F 3 31  ? 196.677 186.038 215.390 1.00 39.30  ? 32  U   T OP1   1 
ATOM   10325 O  OP2   . U   F 3 31  ? 195.024 187.360 213.933 1.00 41.58  ? 32  U   T OP2   1 
ATOM   10326 O  "O5'" . U   F 3 31  ? 196.582 188.521 215.572 1.00 39.40  ? 32  U   T "O5'" 1 
ATOM   10327 C  "C5'" . U   F 3 31  ? 195.441 189.282 216.018 1.00 38.66  ? 32  U   T "C5'" 1 
ATOM   10328 C  "C4'" . U   F 3 31  ? 195.862 190.691 216.358 1.00 35.46  ? 32  U   T "C4'" 1 
ATOM   10329 O  "O4'" . U   F 3 31  ? 196.811 191.194 215.379 1.00 34.03  ? 32  U   T "O4'" 1 
ATOM   10330 C  "C3'" . U   F 3 31  ? 194.724 191.715 216.356 1.00 36.29  ? 32  U   T "C3'" 1 
ATOM   10331 O  "O3'" . U   F 3 31  ? 194.988 192.723 217.318 1.00 41.24  ? 32  U   T "O3'" 1 
ATOM   10332 C  "C2'" . U   F 3 31  ? 194.764 192.257 214.924 1.00 33.62  ? 32  U   T "C2'" 1 
ATOM   10333 O  "O2'" . U   F 3 31  ? 194.168 193.529 214.800 1.00 34.29  ? 32  U   T "O2'" 1 
ATOM   10334 C  "C1'" . U   F 3 31  ? 196.276 192.335 214.736 1.00 31.84  ? 32  U   T "C1'" 1 
ATOM   10335 N  N1    . U   F 3 31  ? 196.708 192.320 213.327 1.00 28.76  ? 32  U   T N1    1 
ATOM   10336 C  C2    . U   F 3 31  ? 197.209 193.498 212.799 1.00 27.76  ? 32  U   T C2    1 
ATOM   10337 O  O2    . U   F 3 31  ? 197.279 194.537 213.440 1.00 28.99  ? 32  U   T O2    1 
ATOM   10338 N  N3    . U   F 3 31  ? 197.631 193.420 211.498 1.00 26.72  ? 32  U   T N3    1 
ATOM   10339 C  C4    . U   F 3 31  ? 197.601 192.304 210.687 1.00 28.61  ? 32  U   T C4    1 
ATOM   10340 O  O4    . U   F 3 31  ? 198.014 192.386 209.533 1.00 30.38  ? 32  U   T O4    1 
ATOM   10341 C  C5    . U   F 3 31  ? 197.052 191.127 211.299 1.00 28.71  ? 32  U   T C5    1 
ATOM   10342 C  C6    . U   F 3 31  ? 196.646 191.172 212.578 1.00 28.95  ? 32  U   T C6    1 
ATOM   10343 P  P     . G   F 3 32  ? 193.900 193.092 218.433 1.00 45.12  ? 33  G   T P     1 
ATOM   10344 O  OP1   . G   F 3 32  ? 192.730 192.183 218.276 1.00 46.59  ? 33  G   T OP1   1 
ATOM   10345 O  OP2   . G   F 3 32  ? 193.673 194.567 218.401 1.00 52.07  ? 33  G   T OP2   1 
ATOM   10346 O  "O5'" . G   F 3 32  ? 194.645 192.754 219.807 1.00 46.83  ? 33  G   T "O5'" 1 
ATOM   10347 C  "C5'" . G   F 3 32  ? 194.665 191.379 220.235 1.00 50.41  ? 33  G   T "C5'" 1 
ATOM   10348 C  "C4'" . G   F 3 32  ? 195.478 191.233 221.495 1.00 49.20  ? 33  G   T "C4'" 1 
ATOM   10349 O  "O4'" . G   F 3 32  ? 194.708 191.703 222.632 1.00 53.02  ? 33  G   T "O4'" 1 
ATOM   10350 C  "C3'" . G   F 3 32  ? 195.851 189.788 221.840 1.00 47.88  ? 33  G   T "C3'" 1 
ATOM   10351 O  "O3'" . G   F 3 32  ? 197.091 189.757 222.523 1.00 40.21  ? 33  G   T "O3'" 1 
ATOM   10352 C  "C2'" . G   F 3 32  ? 194.699 189.363 222.749 1.00 51.36  ? 33  G   T "C2'" 1 
ATOM   10353 O  "O2'" . G   F 3 32  ? 195.026 188.260 223.567 1.00 55.67  ? 33  G   T "O2'" 1 
ATOM   10354 C  "C1'" . G   F 3 32  ? 194.512 190.648 223.548 1.00 55.07  ? 33  G   T "C1'" 1 
ATOM   10355 N  N9    . G   F 3 32  ? 193.190 190.782 224.150 1.00 63.70  ? 33  G   T N9    1 
ATOM   10356 C  C8    . G   F 3 32  ? 192.863 190.554 225.463 1.00 66.23  ? 33  G   T C8    1 
ATOM   10357 N  N7    . G   F 3 32  ? 191.593 190.749 225.722 1.00 69.54  ? 33  G   T N7    1 
ATOM   10358 C  C5    . G   F 3 32  ? 191.050 191.125 224.500 1.00 71.37  ? 33  G   T C5    1 
ATOM   10359 C  C6    . G   F 3 32  ? 189.718 191.468 224.162 1.00 75.93  ? 33  G   T C6    1 
ATOM   10360 O  O6    . G   F 3 32  ? 188.723 191.500 224.899 1.00 80.92  ? 33  G   T O6    1 
ATOM   10361 N  N1    . G   F 3 32  ? 189.600 191.788 222.809 1.00 75.17  ? 33  G   T N1    1 
ATOM   10362 C  C2    . G   F 3 32  ? 190.632 191.787 221.903 1.00 73.98  ? 33  G   T C2    1 
ATOM   10363 N  N2    . G   F 3 32  ? 190.326 192.130 220.645 1.00 74.54  ? 33  G   T N2    1 
ATOM   10364 N  N3    . G   F 3 32  ? 191.887 191.470 222.215 1.00 71.28  ? 33  G   T N3    1 
ATOM   10365 C  C4    . G   F 3 32  ? 192.021 191.150 223.524 1.00 68.30  ? 33  G   T C4    1 
ATOM   10366 P  P     . A   F 3 33  ? 198.459 189.686 221.695 1.00 35.46  ? 34  A   T P     1 
ATOM   10367 O  OP1   . A   F 3 33  ? 198.168 189.636 220.234 1.00 36.48  ? 34  A   T OP1   1 
ATOM   10368 O  OP2   . A   F 3 33  ? 199.315 188.617 222.286 1.00 40.00  ? 34  A   T OP2   1 
ATOM   10369 O  "O5'" . A   F 3 33  ? 199.181 191.080 222.002 1.00 33.61  ? 34  A   T "O5'" 1 
ATOM   10370 C  "C5'" . A   F 3 33  ? 199.097 191.640 223.337 1.00 30.29  ? 34  A   T "C5'" 1 
ATOM   10371 C  "C4'" . A   F 3 33  ? 199.804 192.973 223.390 1.00 29.98  ? 34  A   T "C4'" 1 
ATOM   10372 O  "O4'" . A   F 3 33  ? 201.243 192.770 223.366 1.00 29.28  ? 34  A   T "O4'" 1 
ATOM   10373 C  "C3'" . A   F 3 33  ? 199.508 193.950 222.248 1.00 29.10  ? 34  A   T "C3'" 1 
ATOM   10374 O  "O3'" . A   F 3 33  ? 199.493 195.272 222.754 1.00 31.89  ? 34  A   T "O3'" 1 
ATOM   10375 C  "C2'" . A   F 3 33  ? 200.700 193.745 221.314 1.00 28.49  ? 34  A   T "C2'" 1 
ATOM   10376 O  "O2'" . A   F 3 33  ? 200.952 194.850 220.476 1.00 29.11  ? 34  A   T "O2'" 1 
ATOM   10377 C  "C1'" . A   F 3 33  ? 201.813 193.537 222.334 1.00 27.74  ? 34  A   T "C1'" 1 
ATOM   10378 N  N9    . A   F 3 33  ? 202.984 192.842 221.816 1.00 26.04  ? 34  A   T N9    1 
ATOM   10379 C  C8    . A   F 3 33  ? 203.122 191.511 221.518 1.00 25.81  ? 34  A   T C8    1 
ATOM   10380 N  N7    . A   F 3 33  ? 204.307 191.201 221.049 1.00 26.31  ? 34  A   T N7    1 
ATOM   10381 C  C5    . A   F 3 33  ? 204.996 192.406 221.044 1.00 24.51  ? 34  A   T C5    1 
ATOM   10382 C  C6    . A   F 3 33  ? 206.304 192.752 220.656 1.00 23.10  ? 34  A   T C6    1 
ATOM   10383 N  N6    . A   F 3 33  ? 207.202 191.893 220.191 1.00 24.35  ? 34  A   T N6    1 
ATOM   10384 N  N1    . A   F 3 33  ? 206.669 194.043 220.781 1.00 23.26  ? 34  A   T N1    1 
ATOM   10385 C  C2    . A   F 3 33  ? 205.775 194.920 221.256 1.00 23.97  ? 34  A   T C2    1 
ATOM   10386 N  N3    . A   F 3 33  ? 204.519 194.717 221.644 1.00 23.71  ? 34  A   T N3    1 
ATOM   10387 C  C4    . A   F 3 33  ? 204.191 193.422 221.517 1.00 24.59  ? 34  A   T C4    1 
ATOM   10388 P  P     . A   F 3 34  ? 198.119 196.089 222.857 1.00 36.37  ? 35  A   T P     1 
ATOM   10389 O  OP1   . A   F 3 34  ? 197.247 195.699 221.715 1.00 37.83  ? 35  A   T OP1   1 
ATOM   10390 O  OP2   . A   F 3 34  ? 198.441 197.531 223.066 1.00 39.12  ? 35  A   T OP2   1 
ATOM   10391 O  "O5'" . A   F 3 34  ? 197.442 195.536 224.191 1.00 39.22  ? 35  A   T "O5'" 1 
ATOM   10392 C  "C5'" . A   F 3 34  ? 198.019 195.869 225.480 1.00 41.53  ? 35  A   T "C5'" 1 
ATOM   10393 C  "C4'" . A   F 3 34  ? 197.150 195.314 226.582 1.00 42.34  ? 35  A   T "C4'" 1 
ATOM   10394 O  "O4'" . A   F 3 34  ? 195.757 195.591 226.288 1.00 44.94  ? 35  A   T "O4'" 1 
ATOM   10395 C  "C3'" . A   F 3 34  ? 197.222 193.798 226.791 1.00 43.12  ? 35  A   T "C3'" 1 
ATOM   10396 O  "O3'" . A   F 3 34  ? 197.025 193.473 228.155 1.00 45.66  ? 35  A   T "O3'" 1 
ATOM   10397 C  "C2'" . A   F 3 34  ? 196.054 193.291 225.944 1.00 44.83  ? 35  A   T "C2'" 1 
ATOM   10398 O  "O2'" . A   F 3 34  ? 195.578 192.023 226.339 1.00 44.66  ? 35  A   T "O2'" 1 
ATOM   10399 C  "C1'" . A   F 3 34  ? 195.027 194.389 226.199 1.00 47.31  ? 35  A   T "C1'" 1 
ATOM   10400 N  N9    . A   F 3 34  ? 194.034 194.535 225.140 1.00 55.71  ? 35  A   T N9    1 
ATOM   10401 C  C8    . A   F 3 34  ? 194.269 194.661 223.793 1.00 58.29  ? 35  A   T C8    1 
ATOM   10402 N  N7    . A   F 3 34  ? 193.180 194.777 223.076 1.00 60.22  ? 35  A   T N7    1 
ATOM   10403 C  C5    . A   F 3 34  ? 192.158 194.730 224.013 1.00 63.69  ? 35  A   T C5    1 
ATOM   10404 C  C6    . A   F 3 34  ? 190.758 194.804 223.886 1.00 67.16  ? 35  A   T C6    1 
ATOM   10405 N  N6    . A   F 3 34  ? 190.131 194.948 222.721 1.00 68.25  ? 35  A   T N6    1 
ATOM   10406 N  N1    . A   F 3 34  ? 190.022 194.727 225.022 1.00 69.76  ? 35  A   T N1    1 
ATOM   10407 C  C2    . A   F 3 34  ? 190.661 194.586 226.191 1.00 70.20  ? 35  A   T C2    1 
ATOM   10408 N  N3    . A   F 3 34  ? 191.967 194.505 226.431 1.00 67.74  ? 35  A   T N3    1 
ATOM   10409 C  C4    . A   F 3 34  ? 192.671 194.583 225.288 1.00 62.44  ? 35  A   T C4    1 
ATOM   10410 P  P     . U   F 3 35  ? 198.278 193.249 229.132 1.00 43.44  ? 36  U   T P     1 
ATOM   10411 O  OP1   . U   F 3 35  ? 197.834 192.590 230.395 1.00 50.11  ? 36  U   T OP1   1 
ATOM   10412 O  OP2   . U   F 3 35  ? 199.048 194.521 229.227 1.00 46.91  ? 36  U   T OP2   1 
ATOM   10413 O  "O5'" . U   F 3 35  ? 199.197 192.206 228.347 1.00 41.59  ? 36  U   T "O5'" 1 
ATOM   10414 C  "C5'" . U   F 3 35  ? 198.718 190.865 228.114 1.00 37.93  ? 36  U   T "C5'" 1 
ATOM   10415 C  "C4'" . U   F 3 35  ? 199.792 190.065 227.422 1.00 36.60  ? 36  U   T "C4'" 1 
ATOM   10416 O  "O4'" . U   F 3 35  ? 200.192 190.725 226.197 1.00 35.58  ? 36  U   T "O4'" 1 
ATOM   10417 C  "C3'" . U   F 3 35  ? 201.101 189.912 228.197 1.00 36.48  ? 36  U   T "C3'" 1 
ATOM   10418 O  "O3'" . U   F 3 35  ? 201.021 188.858 229.145 1.00 38.93  ? 36  U   T "O3'" 1 
ATOM   10419 C  "C2'" . U   F 3 35  ? 202.087 189.606 227.071 1.00 35.38  ? 36  U   T "C2'" 1 
ATOM   10420 O  "O2'" . U   F 3 35  ? 202.011 188.267 226.628 1.00 35.51  ? 36  U   T "O2'" 1 
ATOM   10421 C  "C1'" . U   F 3 35  ? 201.570 190.516 225.958 1.00 33.85  ? 36  U   T "C1'" 1 
ATOM   10422 N  N1    . U   F 3 35  ? 202.241 191.833 225.918 1.00 30.33  ? 36  U   T N1    1 
ATOM   10423 C  C2    . U   F 3 35  ? 203.481 191.906 225.311 1.00 29.89  ? 36  U   T C2    1 
ATOM   10424 O  O2    . U   F 3 35  ? 204.038 190.935 224.818 1.00 29.07  ? 36  U   T O2    1 
ATOM   10425 N  N3    . U   F 3 35  ? 204.049 193.153 225.292 1.00 29.23  ? 36  U   T N3    1 
ATOM   10426 C  C4    . U   F 3 35  ? 203.512 194.315 225.804 1.00 31.44  ? 36  U   T C4    1 
ATOM   10427 O  O4    . U   F 3 35  ? 204.140 195.370 225.714 1.00 31.29  ? 36  U   T O4    1 
ATOM   10428 C  C5    . U   F 3 35  ? 202.225 194.158 226.415 1.00 31.51  ? 36  U   T C5    1 
ATOM   10429 C  C6    . U   F 3 35  ? 201.648 192.948 226.449 1.00 30.52  ? 36  U   T C6    1 
ATOM   10430 P  P     . C   F 3 36  ? 201.895 188.910 230.486 1.00 40.37  ? 37  C   T P     1 
ATOM   10431 O  OP1   . C   F 3 36  ? 201.359 187.892 231.435 1.00 45.47  ? 37  C   T OP1   1 
ATOM   10432 O  OP2   . C   F 3 36  ? 201.964 190.330 230.932 1.00 42.31  ? 37  C   T OP2   1 
ATOM   10433 O  "O5'" . C   F 3 36  ? 203.354 188.490 229.988 1.00 36.61  ? 37  C   T "O5'" 1 
ATOM   10434 C  "C5'" . C   F 3 36  ? 203.523 187.190 229.388 1.00 37.18  ? 37  C   T "C5'" 1 
ATOM   10435 C  "C4'" . C   F 3 36  ? 204.886 187.090 228.753 1.00 37.28  ? 37  C   T "C4'" 1 
ATOM   10436 O  "O4'" . C   F 3 36  ? 204.979 187.999 227.629 1.00 35.78  ? 37  C   T "O4'" 1 
ATOM   10437 C  "C3'" . C   F 3 36  ? 206.070 187.481 229.636 1.00 37.14  ? 37  C   T "C3'" 1 
ATOM   10438 O  "O3'" . C   F 3 36  ? 206.462 186.435 230.507 1.00 40.90  ? 37  C   T "O3'" 1 
ATOM   10439 C  "C2'" . C   F 3 36  ? 207.136 187.771 228.581 1.00 35.59  ? 37  C   T "C2'" 1 
ATOM   10440 O  "O2'" . C   F 3 36  ? 207.704 186.598 228.043 1.00 36.43  ? 37  C   T "O2'" 1 
ATOM   10441 C  "C1'" . C   F 3 36  ? 206.306 188.463 227.496 1.00 33.73  ? 37  C   T "C1'" 1 
ATOM   10442 N  N1    . C   F 3 36  ? 206.316 189.945 227.618 1.00 29.23  ? 37  C   T N1    1 
ATOM   10443 C  C2    . C   F 3 36  ? 207.408 190.643 227.097 1.00 27.36  ? 37  C   T C2    1 
ATOM   10444 O  O2    . C   F 3 36  ? 208.331 190.008 226.565 1.00 26.52  ? 37  C   T O2    1 
ATOM   10445 N  N3    . C   F 3 36  ? 207.432 191.993 227.183 1.00 26.62  ? 37  C   T N3    1 
ATOM   10446 C  C4    . C   F 3 36  ? 206.422 192.651 227.755 1.00 27.22  ? 37  C   T C4    1 
ATOM   10447 N  N4    . C   F 3 36  ? 206.502 193.973 227.808 1.00 26.69  ? 37  C   T N4    1 
ATOM   10448 C  C5    . C   F 3 36  ? 205.301 191.956 228.296 1.00 27.74  ? 37  C   T C5    1 
ATOM   10449 C  C6    . C   F 3 36  ? 205.290 190.616 228.209 1.00 27.56  ? 37  C   T C6    1 
ATOM   10450 P  P     . U   F 3 37  ? 207.015 186.779 231.972 1.00 42.18  ? 38  U   T P     1 
ATOM   10451 O  OP1   . U   F 3 37  ? 206.952 185.550 232.814 1.00 47.32  ? 38  U   T OP1   1 
ATOM   10452 O  OP2   . U   F 3 37  ? 206.321 188.004 232.459 1.00 41.16  ? 38  U   T OP2   1 
ATOM   10453 O  "O5'" . U   F 3 37  ? 208.542 187.150 231.701 1.00 38.45  ? 38  U   T "O5'" 1 
ATOM   10454 C  "C5'" . U   F 3 37  ? 209.387 186.187 231.037 1.00 39.02  ? 38  U   T "C5'" 1 
ATOM   10455 C  "C4'" . U   F 3 37  ? 210.700 186.830 230.655 1.00 38.76  ? 38  U   T "C4'" 1 
ATOM   10456 O  "O4'" . U   F 3 37  ? 210.502 187.798 229.589 1.00 37.32  ? 38  U   T "O4'" 1 
ATOM   10457 C  "C3'" . U   F 3 37  ? 211.397 187.643 231.749 1.00 37.02  ? 38  U   T "C3'" 1 
ATOM   10458 O  "O3'" . U   F 3 37  ? 212.108 186.823 232.659 1.00 41.94  ? 38  U   T "O3'" 1 
ATOM   10459 C  "C2'" . U   F 3 37  ? 212.325 188.528 230.914 1.00 34.62  ? 38  U   T "C2'" 1 
ATOM   10460 O  "O2'" . U   F 3 37  ? 213.478 187.846 230.468 1.00 34.33  ? 38  U   T "O2'" 1 
ATOM   10461 C  "C1'" . U   F 3 37  ? 211.433 188.855 229.718 1.00 32.27  ? 38  U   T "C1'" 1 
ATOM   10462 N  N1    . U   F 3 37  ? 210.699 190.128 229.880 1.00 27.83  ? 38  U   T N1    1 
ATOM   10463 C  C2    . U   F 3 37  ? 211.386 191.296 229.598 1.00 25.34  ? 38  U   T C2    1 
ATOM   10464 O  O2    . U   F 3 37  ? 212.554 191.307 229.239 1.00 24.55  ? 38  U   T O2    1 
ATOM   10465 N  N3    . U   F 3 37  ? 210.655 192.448 229.738 1.00 22.97  ? 38  U   T N3    1 
ATOM   10466 C  C4    . U   F 3 37  ? 209.338 192.551 230.128 1.00 23.08  ? 38  U   T C4    1 
ATOM   10467 O  O4    . U   F 3 37  ? 208.814 193.659 230.217 1.00 22.56  ? 38  U   T O4    1 
ATOM   10468 C  C5    . U   F 3 37  ? 208.696 191.299 230.407 1.00 24.90  ? 38  U   T C5    1 
ATOM   10469 C  C6    . U   F 3 37  ? 209.383 190.156 230.273 1.00 25.36  ? 38  U   T C6    1 
ATOM   10470 P  P     . G   F 3 38  ? 212.182 187.256 234.202 1.00 47.71  ? 39  G   T P     1 
ATOM   10471 O  OP1   . G   F 3 38  ? 213.285 186.504 234.867 1.00 52.34  ? 39  G   T OP1   1 
ATOM   10472 O  OP2   . G   F 3 38  ? 210.812 187.195 234.788 1.00 47.10  ? 39  G   T OP2   1 
ATOM   10473 O  "O5'" . G   F 3 38  ? 212.573 188.804 234.095 1.00 41.79  ? 39  G   T "O5'" 1 
ATOM   10474 C  "C5'" . G   F 3 38  ? 213.624 189.318 234.938 1.00 37.14  ? 39  G   T "C5'" 1 
ATOM   10475 C  "C4'" . G   F 3 38  ? 214.508 190.255 234.159 1.00 33.95  ? 39  G   T "C4'" 1 
ATOM   10476 O  "O4'" . G   F 3 38  ? 213.848 190.699 232.947 1.00 31.09  ? 39  G   T "O4'" 1 
ATOM   10477 C  "C3'" . G   F 3 38  ? 214.842 191.566 234.872 1.00 31.96  ? 39  G   T "C3'" 1 
ATOM   10478 O  "O3'" . G   F 3 38  ? 215.874 191.435 235.830 1.00 32.34  ? 39  G   T "O3'" 1 
ATOM   10479 C  "C2'" . G   F 3 38  ? 215.230 192.457 233.695 1.00 29.52  ? 39  G   T "C2'" 1 
ATOM   10480 O  "O2'" . G   F 3 38  ? 216.528 192.177 233.228 1.00 31.27  ? 39  G   T "O2'" 1 
ATOM   10481 C  "C1'" . G   F 3 38  ? 214.179 192.046 232.671 1.00 28.02  ? 39  G   T "C1'" 1 
ATOM   10482 N  N9    . G   F 3 38  ? 212.961 192.845 232.744 1.00 24.26  ? 39  G   T N9    1 
ATOM   10483 C  C8    . G   F 3 38  ? 211.694 192.380 232.977 1.00 22.39  ? 39  G   T C8    1 
ATOM   10484 N  N7    . G   F 3 38  ? 210.787 193.323 232.995 1.00 22.16  ? 39  G   T N7    1 
ATOM   10485 C  C5    . G   F 3 38  ? 211.505 194.488 232.767 1.00 20.84  ? 39  G   T C5    1 
ATOM   10486 C  C6    . G   F 3 38  ? 211.062 195.828 232.680 1.00 18.48  ? 39  G   T C6    1 
ATOM   10487 O  O6    . G   F 3 38  ? 209.911 196.266 232.790 1.00 17.76  ? 39  G   T O6    1 
ATOM   10488 N  N1    . G   F 3 38  ? 212.119 196.697 232.436 1.00 18.65  ? 39  G   T N1    1 
ATOM   10489 C  C2    . G   F 3 38  ? 213.430 196.334 232.295 1.00 18.96  ? 39  G   T C2    1 
ATOM   10490 N  N2    . G   F 3 38  ? 214.304 197.319 232.067 1.00 19.41  ? 39  G   T N2    1 
ATOM   10491 N  N3    . G   F 3 38  ? 213.857 195.075 232.369 1.00 20.74  ? 39  G   T N3    1 
ATOM   10492 C  C4    . G   F 3 38  ? 212.843 194.208 232.604 1.00 21.77  ? 39  G   T C4    1 
ATOM   10493 P  P     . A   F 3 39  ? 215.681 192.127 237.260 1.00 32.64  ? 40  A   T P     1 
ATOM   10494 O  OP1   . A   F 3 39  ? 216.786 191.707 238.171 1.00 35.14  ? 40  A   T OP1   1 
ATOM   10495 O  OP2   . A   F 3 39  ? 214.268 191.978 237.710 1.00 30.77  ? 40  A   T OP2   1 
ATOM   10496 O  "O5'" . A   F 3 39  ? 215.866 193.676 236.922 1.00 29.10  ? 40  A   T "O5'" 1 
ATOM   10497 C  "C5'" . A   F 3 39  ? 217.085 194.138 236.294 1.00 27.27  ? 40  A   T "C5'" 1 
ATOM   10498 C  "C4'" . A   F 3 39  ? 217.020 195.636 236.105 1.00 26.96  ? 40  A   T "C4'" 1 
ATOM   10499 O  "O4'" . A   F 3 39  ? 216.063 195.978 235.067 1.00 25.95  ? 40  A   T "O4'" 1 
ATOM   10500 C  "C3'" . A   F 3 39  ? 216.543 196.438 237.317 1.00 26.22  ? 40  A   T "C3'" 1 
ATOM   10501 O  "O3'" . A   F 3 39  ? 217.583 196.636 238.259 1.00 28.40  ? 40  A   T "O3'" 1 
ATOM   10502 C  "C2'" . A   F 3 39  ? 216.089 197.737 236.654 1.00 25.15  ? 40  A   T "C2'" 1 
ATOM   10503 O  "O2'" . A   F 3 39  ? 217.173 198.579 236.342 1.00 25.21  ? 40  A   T "O2'" 1 
ATOM   10504 C  "C1'" . A   F 3 39  ? 215.449 197.214 235.365 1.00 24.30  ? 40  A   T "C1'" 1 
ATOM   10505 N  N9    . A   F 3 39  ? 214.005 197.029 235.470 1.00 21.77  ? 40  A   T N9    1 
ATOM   10506 C  C8    . A   F 3 39  ? 213.319 195.848 235.591 1.00 21.16  ? 40  A   T C8    1 
ATOM   10507 N  N7    . A   F 3 39  ? 212.024 196.002 235.680 1.00 21.26  ? 40  A   T N7    1 
ATOM   10508 C  C5    . A   F 3 39  ? 211.837 197.376 235.609 1.00 20.55  ? 40  A   T C5    1 
ATOM   10509 C  C6    . A   F 3 39  ? 210.683 198.177 235.638 1.00 19.61  ? 40  A   T C6    1 
ATOM   10510 N  N6    . A   F 3 39  ? 209.451 197.692 235.752 1.00 19.87  ? 40  A   T N6    1 
ATOM   10511 N  N1    . A   F 3 39  ? 210.848 199.517 235.547 1.00 20.24  ? 40  A   T N1    1 
ATOM   10512 C  C2    . A   F 3 39  ? 212.090 200.000 235.429 1.00 20.83  ? 40  A   T C2    1 
ATOM   10513 N  N3    . A   F 3 39  ? 213.248 199.344 235.388 1.00 20.22  ? 40  A   T N3    1 
ATOM   10514 C  C4    . A   F 3 39  ? 213.051 198.020 235.481 1.00 20.90  ? 40  A   T C4    1 
ATOM   10515 P  P     . C   F 3 40  ? 217.253 196.614 239.827 1.00 30.41  ? 41  C   T P     1 
ATOM   10516 O  OP1   . C   F 3 40  ? 218.552 196.705 240.554 1.00 33.43  ? 41  C   T OP1   1 
ATOM   10517 O  OP2   . C   F 3 40  ? 216.340 195.470 240.111 1.00 33.21  ? 41  C   T OP2   1 
ATOM   10518 O  "O5'" . C   F 3 40  ? 216.393 197.934 240.064 1.00 30.59  ? 41  C   T "O5'" 1 
ATOM   10519 C  "C5'" . C   F 3 40  ? 216.977 199.222 239.751 1.00 30.53  ? 41  C   T "C5'" 1 
ATOM   10520 C  "C4'" . C   F 3 40  ? 215.900 200.278 239.744 1.00 30.02  ? 41  C   T "C4'" 1 
ATOM   10521 O  "O4'" . C   F 3 40  ? 214.956 200.033 238.669 1.00 29.15  ? 41  C   T "O4'" 1 
ATOM   10522 C  "C3'" . C   F 3 40  ? 215.025 200.342 240.999 1.00 30.53  ? 41  C   T "C3'" 1 
ATOM   10523 O  "O3'" . C   F 3 40  ? 215.655 201.076 242.031 1.00 35.54  ? 41  C   T "O3'" 1 
ATOM   10524 C  "C2'" . C   F 3 40  ? 213.787 201.059 240.470 1.00 30.25  ? 41  C   T "C2'" 1 
ATOM   10525 O  "O2'" . C   F 3 40  ? 213.976 202.454 240.358 1.00 30.42  ? 41  C   T "O2'" 1 
ATOM   10526 C  "C1'" . C   F 3 40  ? 213.668 200.462 239.060 1.00 29.35  ? 41  C   T "C1'" 1 
ATOM   10527 N  N1    . C   F 3 40  ? 212.734 199.308 239.009 1.00 28.87  ? 41  C   T N1    1 
ATOM   10528 C  C2    . C   F 3 40  ? 211.366 199.573 238.945 1.00 29.49  ? 41  C   T C2    1 
ATOM   10529 O  O2    . C   F 3 40  ? 210.990 200.755 238.938 1.00 32.08  ? 41  C   T O2    1 
ATOM   10530 N  N3    . C   F 3 40  ? 210.495 198.536 238.893 1.00 28.58  ? 41  C   T N3    1 
ATOM   10531 C  C4    . C   F 3 40  ? 210.949 197.279 238.901 1.00 28.17  ? 41  C   T C4    1 
ATOM   10532 N  N4    . C   F 3 40  ? 210.057 196.303 238.854 1.00 30.74  ? 41  C   T N4    1 
ATOM   10533 C  C5    . C   F 3 40  ? 212.338 196.990 238.964 1.00 27.25  ? 41  C   T C5    1 
ATOM   10534 C  C6    . C   F 3 40  ? 213.188 198.022 239.013 1.00 28.09  ? 41  C   T C6    1 
ATOM   10535 P  P     . A   F 3 41  ? 215.719 200.486 243.523 1.00 37.28  ? 42  A   T P     1 
ATOM   10536 O  OP1   . A   F 3 41  ? 216.630 201.357 244.311 1.00 39.96  ? 42  A   T OP1   1 
ATOM   10537 O  OP2   . A   F 3 41  ? 216.019 199.030 243.426 1.00 38.32  ? 42  A   T OP2   1 
ATOM   10538 O  "O5'" . A   F 3 41  ? 214.220 200.641 244.055 1.00 36.03  ? 42  A   T "O5'" 1 
ATOM   10539 C  "C5'" . A   F 3 41  ? 213.603 201.951 244.102 1.00 35.79  ? 42  A   T "C5'" 1 
ATOM   10540 C  "C4'" . A   F 3 41  ? 212.121 201.825 244.378 1.00 37.45  ? 42  A   T "C4'" 1 
ATOM   10541 O  "O4'" . A   F 3 41  ? 211.544 200.826 243.501 1.00 37.54  ? 42  A   T "O4'" 1 
ATOM   10542 C  "C3'" . A   F 3 41  ? 211.726 201.388 245.799 1.00 39.27  ? 42  A   T "C3'" 1 
ATOM   10543 O  "O3'" . A   F 3 41  ? 210.488 201.959 246.193 1.00 43.42  ? 42  A   T "O3'" 1 
ATOM   10544 C  "C2'" . A   F 3 41  ? 211.587 199.873 245.655 1.00 39.17  ? 42  A   T "C2'" 1 
ATOM   10545 O  "O2'" . A   F 3 41  ? 210.741 199.295 246.628 1.00 38.80  ? 42  A   T "O2'" 1 
ATOM   10546 C  "C1'" . A   F 3 41  ? 210.989 199.772 244.252 1.00 37.71  ? 42  A   T "C1'" 1 
ATOM   10547 N  N9    . A   F 3 41  ? 211.309 198.523 243.573 1.00 35.88  ? 42  A   T N9    1 
ATOM   10548 C  C8    . A   F 3 41  ? 212.561 197.980 243.434 1.00 35.12  ? 42  A   T C8    1 
ATOM   10549 N  N7    . A   F 3 41  ? 212.569 196.842 242.788 1.00 36.01  ? 42  A   T N7    1 
ATOM   10550 C  C5    . A   F 3 41  ? 211.234 196.619 242.484 1.00 35.83  ? 42  A   T C5    1 
ATOM   10551 C  C6    . A   F 3 41  ? 210.589 195.568 241.810 1.00 35.38  ? 42  A   T C6    1 
ATOM   10552 N  N6    . A   F 3 41  ? 211.235 194.528 241.292 1.00 37.19  ? 42  A   T N6    1 
ATOM   10553 N  N1    . A   F 3 41  ? 209.245 195.647 241.672 1.00 36.34  ? 42  A   T N1    1 
ATOM   10554 C  C2    . A   F 3 41  ? 208.611 196.712 242.184 1.00 37.66  ? 42  A   T C2    1 
ATOM   10555 N  N3    . A   F 3 41  ? 209.112 197.755 242.839 1.00 36.94  ? 42  A   T N3    1 
ATOM   10556 C  C4    . A   F 3 41  ? 210.445 197.648 242.962 1.00 35.00  ? 42  A   T C4    1 
ATOM   10557 P  P     . A   F 3 42  ? 210.385 203.501 246.624 1.00 47.08  ? 43  A   T P     1 
ATOM   10558 O  OP1   . A   F 3 42  ? 209.272 204.119 245.849 1.00 52.29  ? 43  A   T OP1   1 
ATOM   10559 O  OP2   . A   F 3 42  ? 211.745 204.105 246.540 1.00 48.50  ? 43  A   T OP2   1 
ATOM   10560 O  "O5'" . A   F 3 42  ? 209.945 203.492 248.161 1.00 47.55  ? 43  A   T "O5'" 1 
ATOM   10561 C  "C5'" . A   F 3 42  ? 210.609 202.609 249.090 1.00 48.30  ? 43  A   T "C5'" 1 
ATOM   10562 C  "C4'" . A   F 3 42  ? 211.120 203.386 250.282 1.00 48.46  ? 43  A   T "C4'" 1 
ATOM   10563 O  "O4'" . A   F 3 42  ? 212.554 203.193 250.387 1.00 49.71  ? 43  A   T "O4'" 1 
ATOM   10564 C  "C3'" . A   F 3 42  ? 210.927 204.907 250.247 1.00 50.25  ? 43  A   T "C3'" 1 
ATOM   10565 O  "O3'" . A   F 3 42  ? 210.767 205.426 251.556 1.00 50.89  ? 43  A   T "O3'" 1 
ATOM   10566 C  "C2'" . A   F 3 42  ? 212.232 205.394 249.615 1.00 50.50  ? 43  A   T "C2'" 1 
ATOM   10567 O  "O2'" . A   F 3 42  ? 212.570 206.721 249.952 1.00 48.63  ? 43  A   T "O2'" 1 
ATOM   10568 C  "C1'" . A   F 3 42  ? 213.240 204.408 250.199 1.00 48.69  ? 43  A   T "C1'" 1 
ATOM   10569 N  N9    . A   F 3 42  ? 214.377 204.132 249.329 1.00 47.31  ? 43  A   T N9    1 
ATOM   10570 C  C8    . A   F 3 42  ? 214.412 204.223 247.959 1.00 48.93  ? 43  A   T C8    1 
ATOM   10571 N  N7    . A   F 3 42  ? 215.568 203.889 247.446 1.00 50.54  ? 43  A   T N7    1 
ATOM   10572 C  C5    . A   F 3 42  ? 216.347 203.561 248.547 1.00 47.46  ? 43  A   T C5    1 
ATOM   10573 C  C6    . A   F 3 42  ? 217.685 203.139 248.664 1.00 48.80  ? 43  A   T C6    1 
ATOM   10574 N  N6    . A   F 3 42  ? 218.496 202.965 247.622 1.00 51.89  ? 43  A   T N6    1 
ATOM   10575 N  N1    . A   F 3 42  ? 218.159 202.906 249.912 1.00 48.37  ? 43  A   T N1    1 
ATOM   10576 C  C2    . A   F 3 42  ? 217.333 203.084 250.953 1.00 47.57  ? 43  A   T C2    1 
ATOM   10577 N  N3    . A   F 3 42  ? 216.059 203.472 250.962 1.00 46.06  ? 43  A   T N3    1 
ATOM   10578 C  C4    . A   F 3 42  ? 215.622 203.703 249.714 1.00 44.71  ? 43  A   T C4    1 
ATOM   10579 P  P     . C   F 3 43  ? 209.479 205.043 252.438 1.00 50.89  ? 44  C   T P     1 
ATOM   10580 O  OP1   . C   F 3 43  ? 209.953 204.380 253.684 1.00 53.13  ? 44  C   T OP1   1 
ATOM   10581 O  OP2   . C   F 3 43  ? 208.490 204.330 251.579 1.00 50.93  ? 44  C   T OP2   1 
ATOM   10582 O  "O5'" . C   F 3 43  ? 208.847 206.449 252.862 1.00 50.00  ? 44  C   T "O5'" 1 
ATOM   10583 C  "C5'" . C   F 3 43  ? 208.883 207.556 251.926 1.00 47.42  ? 44  C   T "C5'" 1 
ATOM   10584 C  "C4'" . C   F 3 43  ? 207.813 208.568 252.265 1.00 45.11  ? 44  C   T "C4'" 1 
ATOM   10585 O  "O4'" . C   F 3 43  ? 206.518 208.094 251.811 1.00 45.82  ? 44  C   T "O4'" 1 
ATOM   10586 C  "C3'" . C   F 3 43  ? 207.624 208.906 253.752 1.00 43.95  ? 44  C   T "C3'" 1 
ATOM   10587 O  "O3'" . C   F 3 43  ? 207.315 210.283 253.882 1.00 42.65  ? 44  C   T "O3'" 1 
ATOM   10588 C  "C2'" . C   F 3 43  ? 206.424 208.046 254.161 1.00 47.16  ? 44  C   T "C2'" 1 
ATOM   10589 O  "O2'" . C   F 3 43  ? 205.702 208.563 255.261 1.00 48.77  ? 44  C   T "O2'" 1 
ATOM   10590 C  "C1'" . C   F 3 43  ? 205.598 208.149 252.879 1.00 46.33  ? 44  C   T "C1'" 1 
ATOM   10591 N  N1    . C   F 3 43  ? 204.587 207.073 252.711 1.00 50.15  ? 44  C   T N1    1 
ATOM   10592 C  C2    . C   F 3 43  ? 204.979 205.739 252.539 1.00 52.69  ? 44  C   T C2    1 
ATOM   10593 O  O2    . C   F 3 43  ? 206.183 205.447 252.547 1.00 53.92  ? 44  C   T O2    1 
ATOM   10594 N  N3    . C   F 3 43  ? 204.029 204.790 252.360 1.00 55.25  ? 44  C   T N3    1 
ATOM   10595 C  C4    . C   F 3 43  ? 202.735 205.122 252.352 1.00 56.46  ? 44  C   T C4    1 
ATOM   10596 N  N4    . C   F 3 43  ? 201.847 204.154 252.180 1.00 57.94  ? 44  C   T N4    1 
ATOM   10597 C  C5    . C   F 3 43  ? 202.321 206.474 252.513 1.00 57.70  ? 44  C   T C5    1 
ATOM   10598 C  C6    . C   F 3 43  ? 203.267 207.406 252.680 1.00 53.06  ? 44  C   T C6    1 
ATOM   10599 P  P     . A   F 3 44  ? 207.776 211.111 255.174 1.00 41.07  ? 45  A   T P     1 
ATOM   10600 O  OP1   . A   F 3 44  ? 208.315 210.167 256.197 1.00 47.89  ? 45  A   T OP1   1 
ATOM   10601 O  OP2   . A   F 3 44  ? 206.682 212.036 255.573 1.00 43.47  ? 45  A   T OP2   1 
ATOM   10602 O  "O5'" . A   F 3 44  ? 209.014 211.974 254.661 1.00 40.29  ? 45  A   T "O5'" 1 
ATOM   10603 C  "C5'" . A   F 3 44  ? 209.139 212.268 253.250 1.00 39.49  ? 45  A   T "C5'" 1 
ATOM   10604 C  "C4'" . A   F 3 44  ? 210.320 213.177 253.029 1.00 36.63  ? 45  A   T "C4'" 1 
ATOM   10605 O  "O4'" . A   F 3 44  ? 209.991 214.520 253.465 1.00 36.47  ? 45  A   T "O4'" 1 
ATOM   10606 C  "C3'" . A   F 3 44  ? 211.579 212.820 253.821 1.00 38.41  ? 45  A   T "C3'" 1 
ATOM   10607 O  "O3'" . A   F 3 44  ? 212.355 211.820 253.181 1.00 38.71  ? 45  A   T "O3'" 1 
ATOM   10608 C  "C2'" . A   F 3 44  ? 212.286 214.172 253.881 1.00 36.77  ? 45  A   T "C2'" 1 
ATOM   10609 O  "O2'" . A   F 3 44  ? 212.938 214.498 252.674 1.00 38.02  ? 45  A   T "O2'" 1 
ATOM   10610 C  "C1'" . A   F 3 44  ? 211.103 215.110 254.104 1.00 35.34  ? 45  A   T "C1'" 1 
ATOM   10611 N  N9    . A   F 3 44  ? 210.780 215.305 255.512 1.00 33.07  ? 45  A   T N9    1 
ATOM   10612 C  C8    . A   F 3 44  ? 209.658 214.868 256.170 1.00 32.09  ? 45  A   T C8    1 
ATOM   10613 N  N7    . A   F 3 44  ? 209.637 215.188 257.439 1.00 31.98  ? 45  A   T N7    1 
ATOM   10614 C  C5    . A   F 3 44  ? 210.825 215.876 257.633 1.00 32.13  ? 45  A   T C5    1 
ATOM   10615 C  C6    . A   F 3 44  ? 211.393 216.477 258.771 1.00 31.76  ? 45  A   T C6    1 
ATOM   10616 N  N6    . A   F 3 44  ? 210.813 216.482 259.968 1.00 34.12  ? 45  A   T N6    1 
ATOM   10617 N  N1    . A   F 3 44  ? 212.593 217.084 258.621 1.00 31.54  ? 45  A   T N1    1 
ATOM   10618 C  C2    . A   F 3 44  ? 213.167 217.076 257.413 1.00 31.38  ? 45  A   T C2    1 
ATOM   10619 N  N3    . A   F 3 44  ? 212.727 216.546 256.277 1.00 31.91  ? 45  A   T N3    1 
ATOM   10620 C  C4    . A   F 3 44  ? 211.539 215.951 256.455 1.00 30.89  ? 45  A   T C4    1 
ATOM   10621 P  P     . G   F 3 45  ? 213.056 210.675 254.056 1.00 41.90  ? 46  G   T P     1 
ATOM   10622 O  OP1   . G   F 3 45  ? 213.657 209.661 253.145 1.00 45.82  ? 46  G   T OP1   1 
ATOM   10623 O  OP2   . G   F 3 45  ? 212.087 210.226 255.098 1.00 46.14  ? 46  G   T OP2   1 
ATOM   10624 O  "O5'" . G   F 3 45  ? 214.243 211.437 254.806 1.00 39.23  ? 46  G   T "O5'" 1 
ATOM   10625 C  "C5'" . G   F 3 45  ? 215.295 212.014 254.008 1.00 36.68  ? 46  G   T "C5'" 1 
ATOM   10626 C  "C4'" . G   F 3 45  ? 216.203 212.850 254.874 1.00 37.17  ? 46  G   T "C4'" 1 
ATOM   10627 O  "O4'" . G   F 3 45  ? 215.461 213.948 255.456 1.00 35.80  ? 46  G   T "O4'" 1 
ATOM   10628 C  "C3'" . G   F 3 45  ? 216.812 212.157 256.092 1.00 38.53  ? 46  G   T "C3'" 1 
ATOM   10629 O  "O3'" . G   F 3 45  ? 217.929 211.352 255.759 1.00 42.04  ? 46  G   T "O3'" 1 
ATOM   10630 C  "C2'" . G   F 3 45  ? 217.201 213.366 256.941 1.00 37.18  ? 46  G   T "C2'" 1 
ATOM   10631 O  "O2'" . G   F 3 45  ? 218.373 214.002 256.482 1.00 38.21  ? 46  G   T "O2'" 1 
ATOM   10632 C  "C1'" . G   F 3 45  ? 215.998 214.273 256.721 1.00 35.60  ? 46  G   T "C1'" 1 
ATOM   10633 N  N9    . G   F 3 45  ? 214.963 214.109 257.735 1.00 32.94  ? 46  G   T N9    1 
ATOM   10634 C  C8    . G   F 3 45  ? 213.741 213.505 257.596 1.00 32.93  ? 46  G   T C8    1 
ATOM   10635 N  N7    . G   F 3 45  ? 213.038 213.508 258.705 1.00 33.40  ? 46  G   T N7    1 
ATOM   10636 C  C5    . G   F 3 45  ? 213.853 214.157 259.627 1.00 33.48  ? 46  G   T C5    1 
ATOM   10637 C  C6    . G   F 3 45  ? 213.636 214.460 260.995 1.00 34.19  ? 46  G   T C6    1 
ATOM   10638 O  O6    . G   F 3 45  ? 212.642 214.220 261.693 1.00 36.44  ? 46  G   T O6    1 
ATOM   10639 N  N1    . G   F 3 45  ? 214.725 215.128 261.549 1.00 33.79  ? 46  G   T N1    1 
ATOM   10640 C  C2    . G   F 3 45  ? 215.877 215.450 260.880 1.00 34.05  ? 46  G   T C2    1 
ATOM   10641 N  N2    . G   F 3 45  ? 216.819 216.088 261.581 1.00 36.10  ? 46  G   T N2    1 
ATOM   10642 N  N3    . G   F 3 45  ? 216.091 215.166 259.598 1.00 32.77  ? 46  G   T N3    1 
ATOM   10643 C  C4    . G   F 3 45  ? 215.041 214.524 259.040 1.00 31.70  ? 46  G   T C4    1 
ATOM   10644 P  P     . A   F 3 46  ? 218.246 210.046 256.630 1.00 45.93  ? 47  A   T P     1 
ATOM   10645 O  OP1   . A   F 3 46  ? 219.288 209.249 255.918 1.00 48.03  ? 47  A   T OP1   1 
ATOM   10646 O  OP2   . A   F 3 46  ? 216.961 209.388 256.998 1.00 44.08  ? 47  A   T OP2   1 
ATOM   10647 O  "O5'" . A   F 3 46  ? 218.850 210.639 257.985 1.00 47.48  ? 47  A   T "O5'" 1 
ATOM   10648 C  "C5'" . A   F 3 46  ? 220.100 211.375 257.935 1.00 48.50  ? 47  A   T "C5'" 1 
ATOM   10649 C  "C4'" . A   F 3 46  ? 220.434 211.911 259.305 1.00 50.31  ? 47  A   T "C4'" 1 
ATOM   10650 O  "O4'" . A   F 3 46  ? 219.473 212.926 259.689 1.00 49.20  ? 47  A   T "O4'" 1 
ATOM   10651 C  "C3'" . A   F 3 46  ? 220.377 210.914 260.465 1.00 52.83  ? 47  A   T "C3'" 1 
ATOM   10652 O  "O3'" . A   F 3 46  ? 221.521 210.084 260.538 1.00 56.76  ? 47  A   T "O3'" 1 
ATOM   10653 C  "C2'" . A   F 3 46  ? 220.264 211.873 261.651 1.00 52.11  ? 47  A   T "C2'" 1 
ATOM   10654 O  "O2'" . A   F 3 46  ? 221.496 212.477 261.971 1.00 55.44  ? 47  A   T "O2'" 1 
ATOM   10655 C  "C1'" . A   F 3 46  ? 219.304 212.918 261.092 1.00 47.92  ? 47  A   T "C1'" 1 
ATOM   10656 N  N9    . A   F 3 46  ? 217.914 212.624 261.415 1.00 43.92  ? 47  A   T N9    1 
ATOM   10657 C  C8    . A   F 3 46  ? 216.966 212.027 260.622 1.00 43.32  ? 47  A   T C8    1 
ATOM   10658 N  N7    . A   F 3 46  ? 215.807 211.884 261.217 1.00 43.42  ? 47  A   T N7    1 
ATOM   10659 C  C5    . A   F 3 46  ? 216.005 212.418 262.482 1.00 42.69  ? 47  A   T C5    1 
ATOM   10660 C  C6    . A   F 3 46  ? 215.155 212.563 263.592 1.00 41.01  ? 47  A   T C6    1 
ATOM   10661 N  N6    . A   F 3 46  ? 213.884 212.172 263.606 1.00 41.74  ? 47  A   T N6    1 
ATOM   10662 N  N1    . A   F 3 46  ? 215.670 213.137 264.703 1.00 41.14  ? 47  A   T N1    1 
ATOM   10663 C  C2    . A   F 3 46  ? 216.951 213.532 264.686 1.00 44.11  ? 47  A   T C2    1 
ATOM   10664 N  N3    . A   F 3 46  ? 217.845 213.446 263.704 1.00 43.87  ? 47  A   T N3    1 
ATOM   10665 C  C4    . A   F 3 46  ? 217.303 212.871 262.617 1.00 43.94  ? 47  A   T C4    1 
ATOM   10666 P  P     . G   F 3 47  ? 221.377 208.596 261.124 1.00 59.75  ? 48  G   T P     1 
ATOM   10667 O  OP1   . G   F 3 47  ? 222.649 207.851 260.901 1.00 65.15  ? 48  G   T OP1   1 
ATOM   10668 O  OP2   . G   F 3 47  ? 220.110 208.013 260.600 1.00 58.13  ? 48  G   T OP2   1 
ATOM   10669 O  "O5'" . G   F 3 47  ? 221.165 208.823 262.693 1.00 60.54  ? 48  G   T "O5'" 1 
ATOM   10670 C  "C5'" . G   F 3 47  ? 222.210 209.469 263.462 1.00 63.31  ? 48  G   T "C5'" 1 
ATOM   10671 C  "C4'" . G   F 3 47  ? 221.693 209.827 264.835 1.00 66.51  ? 48  G   T "C4'" 1 
ATOM   10672 O  "O4'" . G   F 3 47  ? 220.546 210.707 264.726 1.00 62.91  ? 48  G   T "O4'" 1 
ATOM   10673 C  "C3'" . G   F 3 47  ? 221.174 208.665 265.684 1.00 68.86  ? 48  G   T "C3'" 1 
ATOM   10674 O  "O3'" . G   F 3 47  ? 222.228 207.954 266.314 1.00 78.46  ? 48  G   T "O3'" 1 
ATOM   10675 C  "C2'" . G   F 3 47  ? 220.284 209.404 266.682 1.00 65.79  ? 48  G   T "C2'" 1 
ATOM   10676 O  "O2'" . G   F 3 47  ? 221.018 210.028 267.713 1.00 69.83  ? 48  G   T "O2'" 1 
ATOM   10677 C  "C1'" . G   F 3 47  ? 219.647 210.467 265.790 1.00 62.19  ? 48  G   T "C1'" 1 
ATOM   10678 N  N9    . G   F 3 47  ? 218.355 210.067 265.244 1.00 55.99  ? 48  G   T N9    1 
ATOM   10679 C  C8    . G   F 3 47  ? 218.101 209.588 263.984 1.00 57.73  ? 48  G   T C8    1 
ATOM   10680 N  N7    . G   F 3 47  ? 216.838 209.295 263.784 1.00 55.14  ? 48  G   T N7    1 
ATOM   10681 C  C5    . G   F 3 47  ? 216.223 209.608 264.988 1.00 52.76  ? 48  G   T C5    1 
ATOM   10682 C  C6    . G   F 3 47  ? 214.862 209.502 265.374 1.00 53.49  ? 48  G   T C6    1 
ATOM   10683 O  O6    . G   F 3 47  ? 213.894 209.112 264.708 1.00 58.52  ? 48  G   T O6    1 
ATOM   10684 N  N1    . G   F 3 47  ? 214.669 209.922 266.689 1.00 54.18  ? 48  G   T N1    1 
ATOM   10685 C  C2    . G   F 3 47  ? 215.656 210.379 267.525 1.00 54.17  ? 48  G   T C2    1 
ATOM   10686 N  N2    . G   F 3 47  ? 215.274 210.734 268.758 1.00 57.62  ? 48  G   T N2    1 
ATOM   10687 N  N3    . G   F 3 47  ? 216.936 210.483 267.171 1.00 52.38  ? 48  G   T N3    1 
ATOM   10688 C  C4    . G   F 3 47  ? 217.147 210.078 265.896 1.00 52.59  ? 48  G   T C4    1 
ATOM   10689 P  P     . G   F 3 48  ? 222.232 206.348 266.301 1.00 86.16  ? 49  G   T P     1 
ATOM   10690 O  OP1   . G   F 3 48  ? 223.638 205.854 266.328 1.00 87.64  ? 49  G   T OP1   1 
ATOM   10691 O  OP2   . G   F 3 48  ? 221.340 205.918 265.185 1.00 85.47  ? 49  G   T OP2   1 
ATOM   10692 O  "O5'" . G   F 3 48  ? 221.538 205.966 267.689 1.00 84.11  ? 49  G   T "O5'" 1 
ATOM   10693 C  "C5'" . G   F 3 48  ? 220.123 205.666 267.693 1.00 85.42  ? 49  G   T "C5'" 1 
ATOM   10694 C  "C4'" . G   F 3 48  ? 219.446 206.465 268.777 1.00 87.73  ? 49  G   T "C4'" 1 
ATOM   10695 O  "O4'" . G   F 3 48  ? 218.423 207.312 268.193 1.00 83.99  ? 49  G   T "O4'" 1 
ATOM   10696 C  "C3'" . G   F 3 48  ? 218.692 205.641 269.823 1.00 91.67  ? 49  G   T "C3'" 1 
ATOM   10697 O  "O3'" . G   F 3 48  ? 219.557 205.199 270.857 1.00 104.31 ? 49  G   T "O3'" 1 
ATOM   10698 C  "C2'" . G   F 3 48  ? 217.651 206.642 270.326 1.00 86.36  ? 49  G   T "C2'" 1 
ATOM   10699 O  "O2'" . G   F 3 48  ? 218.180 207.524 271.292 1.00 87.50  ? 49  G   T "O2'" 1 
ATOM   10700 C  "C1'" . G   F 3 48  ? 217.309 207.415 269.055 1.00 79.81  ? 49  G   T "C1'" 1 
ATOM   10701 N  N9    . G   F 3 48  ? 216.129 206.928 268.348 1.00 71.13  ? 49  G   T N9    1 
ATOM   10702 C  C8    . G   F 3 48  ? 216.095 206.364 267.097 1.00 68.50  ? 49  G   T C8    1 
ATOM   10703 N  N7    . G   F 3 48  ? 214.891 206.032 266.706 1.00 67.15  ? 49  G   T N7    1 
ATOM   10704 C  C5    . G   F 3 48  ? 214.078 206.407 267.766 1.00 65.34  ? 49  G   T C5    1 
ATOM   10705 C  C6    . G   F 3 48  ? 212.675 206.293 267.916 1.00 65.98  ? 49  G   T C6    1 
ATOM   10706 O  O6    . G   F 3 48  ? 211.853 205.825 267.119 1.00 66.16  ? 49  G   T O6    1 
ATOM   10707 N  N1    . G   F 3 48  ? 212.253 206.793 269.145 1.00 67.37  ? 49  G   T N1    1 
ATOM   10708 C  C2    . G   F 3 48  ? 213.076 207.333 270.103 1.00 69.88  ? 49  G   T C2    1 
ATOM   10709 N  N2    . G   F 3 48  ? 212.483 207.765 271.223 1.00 72.08  ? 49  G   T N2    1 
ATOM   10710 N  N3    . G   F 3 48  ? 214.397 207.444 269.970 1.00 68.27  ? 49  G   T N3    1 
ATOM   10711 C  C4    . G   F 3 48  ? 214.826 206.963 268.781 1.00 67.08  ? 49  G   T C4    1 
ATOM   10712 P  P     . C   F 3 49  ? 219.221 203.864 271.683 1.00 113.80 ? 50  C   T P     1 
ATOM   10713 O  OP1   . C   F 3 49  ? 220.376 203.558 272.575 1.00 115.10 ? 50  C   T OP1   1 
ATOM   10714 O  OP2   . C   F 3 49  ? 218.760 202.814 270.729 1.00 112.49 ? 50  C   T OP2   1 
ATOM   10715 O  "O5'" . C   F 3 49  ? 217.982 204.313 272.590 1.00 111.93 ? 50  C   T "O5'" 1 
ATOM   10716 C  "C5'" . C   F 3 49  ? 217.168 203.290 273.206 1.00 112.82 ? 50  C   T "C5'" 1 
ATOM   10717 C  "C4'" . C   F 3 49  ? 215.793 203.839 273.494 1.00 113.55 ? 50  C   T "C4'" 1 
ATOM   10718 O  "O4'" . C   F 3 49  ? 215.350 204.695 272.408 1.00 109.59 ? 50  C   T "O4'" 1 
ATOM   10719 C  "C3'" . C   F 3 49  ? 214.694 202.780 273.613 1.00 116.96 ? 50  C   T "C3'" 1 
ATOM   10720 O  "O3'" . C   F 3 49  ? 214.639 202.211 274.912 1.00 128.33 ? 50  C   T "O3'" 1 
ATOM   10721 C  "C2'" . C   F 3 49  ? 213.439 203.581 273.266 1.00 111.56 ? 50  C   T "C2'" 1 
ATOM   10722 O  "O2'" . C   F 3 49  ? 212.984 204.363 274.348 1.00 111.06 ? 50  C   T "O2'" 1 
ATOM   10723 C  "C1'" . C   F 3 49  ? 213.970 204.506 272.167 1.00 106.00 ? 50  C   T "C1'" 1 
ATOM   10724 N  N1    . C   F 3 49  ? 213.812 203.947 270.799 1.00 96.31  ? 50  C   T N1    1 
ATOM   10725 C  C2    . C   F 3 49  ? 212.536 203.841 270.229 1.00 90.69  ? 50  C   T C2    1 
ATOM   10726 O  O2    . C   F 3 49  ? 211.540 204.204 270.875 1.00 91.51  ? 50  C   T O2    1 
ATOM   10727 N  N3    . C   F 3 49  ? 212.419 203.335 268.979 1.00 88.97  ? 50  C   T N3    1 
ATOM   10728 C  C4    . C   F 3 49  ? 213.505 202.953 268.296 1.00 90.41  ? 50  C   T C4    1 
ATOM   10729 N  N4    . C   F 3 49  ? 213.327 202.467 267.077 1.00 91.76  ? 50  C   T N4    1 
ATOM   10730 C  C5    . C   F 3 49  ? 214.807 203.058 268.856 1.00 90.85  ? 50  C   T C5    1 
ATOM   10731 C  C6    . C   F 3 49  ? 214.914 203.558 270.094 1.00 93.55  ? 50  C   T C6    1 
ATOM   10732 P  P     . U   F 3 50  ? 215.083 200.684 275.137 1.00 136.65 ? 51  U   T P     1 
ATOM   10733 O  OP1   . U   F 3 50  ? 215.312 200.447 276.590 1.00 138.02 ? 51  U   T OP1   1 
ATOM   10734 O  OP2   . U   F 3 50  ? 216.177 200.363 274.176 1.00 136.51 ? 51  U   T OP2   1 
ATOM   10735 O  "O5'" . U   F 3 50  ? 213.805 199.845 274.671 1.00 139.64 ? 51  U   T "O5'" 1 
ATOM   10736 C  "C5'" . U   F 3 50  ? 212.522 200.109 275.291 1.00 145.07 ? 51  U   T "C5'" 1 
ATOM   10737 C  "C4'" . U   F 3 50  ? 211.411 199.709 274.351 1.00 149.31 ? 51  U   T "C4'" 1 
ATOM   10738 O  "O4'" . U   F 3 50  ? 211.418 200.561 273.174 1.00 149.07 ? 51  U   T "O4'" 1 
ATOM   10739 C  "C3'" . U   F 3 50  ? 211.493 198.292 273.775 1.00 152.24 ? 51  U   T "C3'" 1 
ATOM   10740 O  "O3'" . U   F 3 50  ? 211.018 197.304 274.676 1.00 160.42 ? 51  U   T "O3'" 1 
ATOM   10741 C  "C2'" . U   F 3 50  ? 210.610 198.429 272.535 1.00 149.51 ? 51  U   T "C2'" 1 
ATOM   10742 O  "O2'" . U   F 3 50  ? 209.234 198.412 272.847 1.00 147.37 ? 51  U   T "O2'" 1 
ATOM   10743 C  "C1'" . U   F 3 50  ? 211.002 199.823 272.042 1.00 147.07 ? 51  U   T "C1'" 1 
ATOM   10744 N  N1    . U   F 3 50  ? 212.106 199.792 271.055 1.00 140.03 ? 51  U   T N1    1 
ATOM   10745 C  C2    . U   F 3 50  ? 211.775 199.556 269.731 1.00 136.16 ? 51  U   T C2    1 
ATOM   10746 O  O2    . U   F 3 50  ? 210.627 199.379 269.355 1.00 137.49 ? 51  U   T O2    1 
ATOM   10747 N  N3    . U   F 3 50  ? 212.837 199.534 268.861 1.00 132.59 ? 51  U   T N3    1 
ATOM   10748 C  C4    . U   F 3 50  ? 214.170 199.723 269.171 1.00 132.55 ? 51  U   T C4    1 
ATOM   10749 O  O4    . U   F 3 50  ? 215.013 199.675 268.274 1.00 131.16 ? 51  U   T O4    1 
ATOM   10750 C  C5    . U   F 3 50  ? 214.434 199.961 270.560 1.00 134.50 ? 51  U   T C5    1 
ATOM   10751 C  C6    . U   F 3 50  ? 213.415 199.987 271.433 1.00 137.12 ? 51  U   T C6    1 
ATOM   10752 P  P     . U   F 3 51  ? 211.957 196.060 275.066 1.00 167.95 ? 52  U   T P     1 
ATOM   10753 O  OP1   . U   F 3 51  ? 211.631 195.607 276.449 1.00 169.21 ? 52  U   T OP1   1 
ATOM   10754 O  OP2   . U   F 3 51  ? 213.364 196.439 274.755 1.00 166.55 ? 52  U   T OP2   1 
ATOM   10755 O  "O5'" . U   F 3 51  ? 211.478 194.939 274.028 1.00 170.69 ? 52  U   T "O5'" 1 
ATOM   10756 C  "C5'" . U   F 3 51  ? 212.289 193.746 273.845 1.00 175.07 ? 52  U   T "C5'" 1 
ATOM   10757 C  "C4'" . U   F 3 51  ? 211.870 193.041 272.578 1.00 177.72 ? 52  U   T "C4'" 1 
ATOM   10758 O  "O4'" . U   F 3 51  ? 210.571 192.421 272.765 1.00 178.59 ? 52  U   T "O4'" 1 
ATOM   10759 C  "C3'" . U   F 3 51  ? 211.683 193.932 271.346 1.00 179.14 ? 52  U   T "C3'" 1 
ATOM   10760 O  "O3'" . U   F 3 51  ? 212.908 194.205 270.684 1.00 178.36 ? 52  U   T "O3'" 1 
ATOM   10761 C  "C2'" . U   F 3 51  ? 210.737 193.082 270.496 1.00 179.27 ? 52  U   T "C2'" 1 
ATOM   10762 O  "O2'" . U   F 3 51  ? 211.404 192.027 269.837 1.00 179.83 ? 52  U   T "O2'" 1 
ATOM   10763 C  "C1'" . U   F 3 51  ? 209.817 192.500 271.571 1.00 177.83 ? 52  U   T "C1'" 1 
ATOM   10764 N  N1    . U   F 3 51  ? 208.624 193.334 271.825 1.00 175.16 ? 52  U   T N1    1 
ATOM   10765 C  C2    . U   F 3 51  ? 207.592 193.291 270.900 1.00 176.11 ? 52  U   T C2    1 
ATOM   10766 O  O2    . U   F 3 51  ? 207.626 192.604 269.889 1.00 177.12 ? 52  U   T O2    1 
ATOM   10767 N  N3    . U   F 3 51  ? 206.517 194.090 271.200 1.00 176.07 ? 52  U   T N3    1 
ATOM   10768 C  C4    . U   F 3 51  ? 206.368 194.904 272.305 1.00 175.66 ? 52  U   T C4    1 
ATOM   10769 O  O4    . U   F 3 51  ? 205.337 195.563 272.437 1.00 177.54 ? 52  U   T O4    1 
ATOM   10770 C  C5    . U   F 3 51  ? 207.477 194.893 273.213 1.00 174.68 ? 52  U   T C5    1 
ATOM   10771 C  C6    . U   F 3 51  ? 208.542 194.125 272.946 1.00 174.18 ? 52  U   T C6    1 
ATOM   10772 P  P     . A   F 3 52  ? 213.133 195.639 269.999 1.00 176.08 ? 53  A   T P     1 
ATOM   10773 O  OP1   . A   F 3 52  ? 214.531 196.081 270.266 1.00 175.89 ? 53  A   T OP1   1 
ATOM   10774 O  OP2   . A   F 3 52  ? 212.015 196.517 270.443 1.00 174.32 ? 53  A   T OP2   1 
ATOM   10775 O  "O5'" . A   F 3 52  ? 212.936 195.334 268.441 1.00 170.53 ? 53  A   T "O5'" 1 
ATOM   10776 C  "C5'" . A   F 3 52  ? 212.262 196.322 267.619 1.00 169.65 ? 53  A   T "C5'" 1 
ATOM   10777 C  "C4'" . A   F 3 52  ? 211.024 195.720 267.003 1.00 168.48 ? 53  A   T "C4'" 1 
ATOM   10778 O  "O4'" . A   F 3 52  ? 210.169 195.166 268.036 1.00 166.52 ? 53  A   T "O4'" 1 
ATOM   10779 C  "C3'" . A   F 3 52  ? 210.115 196.706 266.266 1.00 169.28 ? 53  A   T "C3'" 1 
ATOM   10780 O  "O3'" . A   F 3 52  ? 210.547 196.962 264.940 1.00 171.42 ? 53  A   T "O3'" 1 
ATOM   10781 C  "C2'" . A   F 3 52  ? 208.774 195.975 266.308 1.00 167.01 ? 53  A   T "C2'" 1 
ATOM   10782 O  "O2'" . A   F 3 52  ? 208.686 194.968 265.324 1.00 166.51 ? 53  A   T "O2'" 1 
ATOM   10783 C  "C1'" . A   F 3 52  ? 208.809 195.350 267.702 1.00 165.32 ? 53  A   T "C1'" 1 
ATOM   10784 N  N9    . A   F 3 52  ? 208.166 196.171 268.726 1.00 163.82 ? 53  A   T N9    1 
ATOM   10785 C  C8    . A   F 3 52  ? 208.757 196.778 269.807 1.00 163.10 ? 53  A   T C8    1 
ATOM   10786 N  N7    . A   F 3 52  ? 207.920 197.455 270.553 1.00 163.08 ? 53  A   T N7    1 
ATOM   10787 C  C5    . A   F 3 52  ? 206.693 197.282 269.929 1.00 164.92 ? 53  A   T C5    1 
ATOM   10788 C  C6    . A   F 3 52  ? 205.401 197.755 270.233 1.00 165.69 ? 53  A   T C6    1 
ATOM   10789 N  N6    . A   F 3 52  ? 205.123 198.523 271.284 1.00 164.99 ? 53  A   T N6    1 
ATOM   10790 N  N1    . A   F 3 52  ? 204.393 197.400 269.399 1.00 166.97 ? 53  A   T N1    1 
ATOM   10791 C  C2    . A   F 3 52  ? 204.679 196.626 268.343 1.00 167.35 ? 53  A   T C2    1 
ATOM   10792 N  N3    . A   F 3 52  ? 205.850 196.126 267.959 1.00 166.10 ? 53  A   T N3    1 
ATOM   10793 C  C4    . A   F 3 52  ? 206.831 196.494 268.801 1.00 165.22 ? 53  A   T C4    1 
ATOM   10794 P  P     . C   F 3 53  ? 210.530 198.459 264.356 1.00 170.97 ? 54  C   T P     1 
ATOM   10795 O  OP1   . C   F 3 53  ? 211.010 198.422 262.946 1.00 169.37 ? 54  C   T OP1   1 
ATOM   10796 O  OP2   . C   F 3 53  ? 211.230 199.350 265.326 1.00 170.12 ? 54  C   T OP2   1 
ATOM   10797 O  "O5'" . C   F 3 53  ? 208.980 198.856 264.389 1.00 175.09 ? 54  C   T "O5'" 1 
ATOM   10798 C  "C5'" . C   F 3 53  ? 208.155 198.589 263.226 1.00 179.56 ? 54  C   T "C5'" 1 
ATOM   10799 C  "C4'" . C   F 3 53  ? 206.795 199.216 263.407 1.00 183.76 ? 54  C   T "C4'" 1 
ATOM   10800 O  "O4'" . C   F 3 53  ? 206.170 198.695 264.609 1.00 184.35 ? 54  C   T "O4'" 1 
ATOM   10801 C  "C3'" . C   F 3 53  ? 206.774 200.738 263.595 1.00 187.98 ? 54  C   T "C3'" 1 
ATOM   10802 O  "O3'" . C   F 3 53  ? 206.816 201.423 262.350 1.00 193.48 ? 54  C   T "O3'" 1 
ATOM   10803 C  "C2'" . C   F 3 53  ? 205.445 200.940 264.328 1.00 186.74 ? 54  C   T "C2'" 1 
ATOM   10804 O  "O2'" . C   F 3 53  ? 204.340 200.917 263.451 1.00 187.17 ? 54  C   T "O2'" 1 
ATOM   10805 C  "C1'" . C   F 3 53  ? 205.391 199.699 265.224 1.00 184.83 ? 54  C   T "C1'" 1 
ATOM   10806 N  N1    . C   F 3 53  ? 205.928 199.952 266.586 1.00 181.89 ? 54  C   T N1    1 
ATOM   10807 C  C2    . C   F 3 53  ? 205.083 200.510 267.552 1.00 180.39 ? 54  C   T C2    1 
ATOM   10808 O  O2    . C   F 3 53  ? 203.914 200.786 267.242 1.00 177.43 ? 54  C   T O2    1 
ATOM   10809 N  N3    . C   F 3 53  ? 205.571 200.736 268.797 1.00 179.62 ? 54  C   T N3    1 
ATOM   10810 C  C4    . C   F 3 53  ? 206.842 200.431 269.093 1.00 179.00 ? 54  C   T C4    1 
ATOM   10811 N  N4    . C   F 3 53  ? 207.271 200.668 270.324 1.00 178.81 ? 54  C   T N4    1 
ATOM   10812 C  C5    . C   F 3 53  ? 207.710 199.860 268.123 1.00 178.31 ? 54  C   T C5    1 
ATOM   10813 C  C6    . C   F 3 53  ? 207.219 199.639 266.896 1.00 179.74 ? 54  C   T C6    1 
ATOM   10814 P  P     . G   F 3 54  ? 208.156 202.186 261.898 1.00 197.45 ? 55  G   T P     1 
ATOM   10815 O  OP1   . G   F 3 54  ? 209.153 201.178 261.437 1.00 194.64 ? 55  G   T OP1   1 
ATOM   10816 O  OP2   . G   F 3 54  ? 208.551 203.130 262.981 1.00 197.03 ? 55  G   T OP2   1 
ATOM   10817 O  "O5'" . G   F 3 54  ? 207.678 203.025 260.622 1.00 198.66 ? 55  G   T "O5'" 1 
ATOM   10818 C  "C5'" . G   F 3 54  ? 207.793 204.474 260.636 1.00 199.95 ? 55  G   T "C5'" 1 
ATOM   10819 C  "C4'" . G   F 3 54  ? 206.428 205.100 260.492 1.00 201.28 ? 55  G   T "C4'" 1 
ATOM   10820 O  "O4'" . G   F 3 54  ? 205.699 204.425 259.433 1.00 203.39 ? 55  G   T "O4'" 1 
ATOM   10821 C  "C3'" . G   F 3 54  ? 205.518 205.021 261.724 1.00 202.33 ? 55  G   T "C3'" 1 
ATOM   10822 O  "O3'" . G   F 3 54  ? 204.671 206.155 261.772 1.00 197.76 ? 55  G   T "O3'" 1 
ATOM   10823 C  "C2'" . G   F 3 54  ? 204.692 203.766 261.442 1.00 204.68 ? 55  G   T "C2'" 1 
ATOM   10824 O  "O2'" . G   F 3 54  ? 203.464 203.724 262.137 1.00 204.61 ? 55  G   T "O2'" 1 
ATOM   10825 C  "C1'" . G   F 3 54  ? 204.492 203.899 259.936 1.00 206.14 ? 55  G   T "C1'" 1 
ATOM   10826 N  N9    . G   F 3 54  ? 204.209 202.639 259.256 1.00 208.60 ? 55  G   T N9    1 
ATOM   10827 C  C8    . G   F 3 54  ? 205.112 201.682 258.866 1.00 208.21 ? 55  G   T C8    1 
ATOM   10828 N  N7    . G   F 3 54  ? 204.554 200.654 258.273 1.00 208.41 ? 55  G   T N7    1 
ATOM   10829 C  C5    . G   F 3 54  ? 203.197 200.954 258.276 1.00 209.55 ? 55  G   T C5    1 
ATOM   10830 C  C6    . G   F 3 54  ? 202.094 200.218 257.775 1.00 210.26 ? 55  G   T C6    1 
ATOM   10831 O  O6    . G   F 3 54  ? 202.099 199.117 257.208 1.00 208.93 ? 55  G   T O6    1 
ATOM   10832 N  N1    . G   F 3 54  ? 200.890 200.892 257.988 1.00 211.80 ? 55  G   T N1    1 
ATOM   10833 C  C2    . G   F 3 54  ? 200.764 202.114 258.603 1.00 212.05 ? 55  G   T C2    1 
ATOM   10834 N  N2    . G   F 3 54  ? 199.526 202.609 258.721 1.00 210.74 ? 55  G   T N2    1 
ATOM   10835 N  N3    . G   F 3 54  ? 201.795 202.810 259.076 1.00 211.61 ? 55  G   T N3    1 
ATOM   10836 C  C4    . G   F 3 54  ? 202.974 202.174 258.877 1.00 210.28 ? 55  G   T C4    1 
ATOM   10837 P  P     . A   F 3 55  ? 204.667 207.139 263.040 1.00 192.48 ? 56  A   T P     1 
ATOM   10838 O  OP1   . A   F 3 55  ? 203.537 208.100 262.888 1.00 191.02 ? 56  A   T OP1   1 
ATOM   10839 O  OP2   . A   F 3 55  ? 206.044 207.681 263.221 1.00 192.54 ? 56  A   T OP2   1 
ATOM   10840 O  "O5'" . A   F 3 55  ? 204.366 206.162 264.271 1.00 181.21 ? 56  A   T "O5'" 1 
ATOM   10841 C  "C5'" . A   F 3 55  ? 202.994 205.773 264.544 1.00 171.03 ? 56  A   T "C5'" 1 
ATOM   10842 C  "C4'" . A   F 3 55  ? 202.848 205.393 265.997 1.00 162.85 ? 56  A   T "C4'" 1 
ATOM   10843 O  "O4'" . A   F 3 55  ? 203.541 204.146 266.261 1.00 157.62 ? 56  A   T "O4'" 1 
ATOM   10844 C  "C3'" . A   F 3 55  ? 203.448 206.372 267.007 1.00 158.25 ? 56  A   T "C3'" 1 
ATOM   10845 O  "O3'" . A   F 3 55  ? 202.570 207.453 267.276 1.00 155.20 ? 56  A   T "O3'" 1 
ATOM   10846 C  "C2'" . A   F 3 55  ? 203.654 205.468 268.222 1.00 155.60 ? 56  A   T "C2'" 1 
ATOM   10847 O  "O2'" . A   F 3 55  ? 202.466 205.279 268.958 1.00 157.82 ? 56  A   T "O2'" 1 
ATOM   10848 C  "C1'" . A   F 3 55  ? 204.077 204.153 267.569 1.00 152.52 ? 56  A   T "C1'" 1 
ATOM   10849 N  N9    . A   F 3 55  ? 205.524 203.968 267.488 1.00 144.71 ? 56  A   T N9    1 
ATOM   10850 C  C8    . A   F 3 55  ? 206.280 203.851 266.348 1.00 141.29 ? 56  A   T C8    1 
ATOM   10851 N  N7    . A   F 3 55  ? 207.559 203.685 266.579 1.00 137.65 ? 56  A   T N7    1 
ATOM   10852 C  C5    . A   F 3 55  ? 207.657 203.692 267.962 1.00 135.27 ? 56  A   T C5    1 
ATOM   10853 C  C6    . A   F 3 55  ? 208.757 203.561 268.830 1.00 132.04 ? 56  A   T C6    1 
ATOM   10854 N  N6    . A   F 3 55  ? 210.008 203.395 268.411 1.00 128.34 ? 56  A   T N6    1 
ATOM   10855 N  N1    . A   F 3 55  ? 208.512 203.612 270.162 1.00 135.80 ? 56  A   T N1    1 
ATOM   10856 C  C2    . A   F 3 55  ? 207.248 203.783 270.573 1.00 138.58 ? 56  A   T C2    1 
ATOM   10857 N  N3    . A   F 3 55  ? 206.137 203.916 269.850 1.00 139.14 ? 56  A   T N3    1 
ATOM   10858 C  C4    . A   F 3 55  ? 206.410 203.860 268.535 1.00 139.40 ? 56  A   T C4    1 
ATOM   10859 P  P     . C   F 3 56  ? 203.130 208.957 267.307 1.00 152.50 ? 57  C   T P     1 
ATOM   10860 O  OP1   . C   F 3 56  ? 201.990 209.904 267.459 1.00 151.34 ? 57  C   T OP1   1 
ATOM   10861 O  OP2   . C   F 3 56  ? 204.056 209.136 266.152 1.00 154.31 ? 57  C   T OP2   1 
ATOM   10862 O  "O5'" . C   F 3 56  ? 204.029 208.990 268.629 1.00 143.21 ? 57  C   T "O5'" 1 
ATOM   10863 C  "C5'" . C   F 3 56  ? 203.407 208.755 269.916 1.00 135.00 ? 57  C   T "C5'" 1 
ATOM   10864 C  "C4'" . C   F 3 56  ? 204.470 208.438 270.937 1.00 129.18 ? 57  C   T "C4'" 1 
ATOM   10865 O  "O4'" . C   F 3 56  ? 205.160 207.214 270.576 1.00 124.14 ? 57  C   T "O4'" 1 
ATOM   10866 C  "C3'" . C   F 3 56  ? 205.590 209.474 271.069 1.00 125.61 ? 57  C   T "C3'" 1 
ATOM   10867 O  "O3'" . C   F 3 56  ? 205.216 210.552 271.911 1.00 124.38 ? 57  C   T "O3'" 1 
ATOM   10868 C  "C2'" . C   F 3 56  ? 206.714 208.633 271.674 1.00 123.78 ? 57  C   T "C2'" 1 
ATOM   10869 O  "O2'" . C   F 3 56  ? 206.549 208.422 273.060 1.00 126.54 ? 57  C   T "O2'" 1 
ATOM   10870 C  "C1'" . C   F 3 56  ? 206.519 207.297 270.949 1.00 121.50 ? 57  C   T "C1'" 1 
ATOM   10871 N  N1    . C   F 3 56  ? 207.357 207.179 269.727 1.00 115.96 ? 57  C   T N1    1 
ATOM   10872 C  C2    . C   F 3 56  ? 208.695 206.800 269.870 1.00 113.10 ? 57  C   T C2    1 
ATOM   10873 O  O2    . C   F 3 56  ? 209.141 206.578 271.006 1.00 114.08 ? 57  C   T O2    1 
ATOM   10874 N  N3    . C   F 3 56  ? 209.467 206.682 268.762 1.00 110.51 ? 57  C   T N3    1 
ATOM   10875 C  C4    . C   F 3 56  ? 208.951 206.927 267.549 1.00 110.17 ? 57  C   T C4    1 
ATOM   10876 N  N4    . C   F 3 56  ? 209.746 206.800 266.496 1.00 109.24 ? 57  C   T N4    1 
ATOM   10877 C  C5    . C   F 3 56  ? 207.591 207.314 267.387 1.00 111.37 ? 57  C   T C5    1 
ATOM   10878 C  C6    . C   F 3 56  ? 206.836 207.426 268.490 1.00 112.80 ? 57  C   T C6    1 
ATOM   10879 P  P     . C   F 3 57  ? 205.658 212.050 271.544 1.00 123.40 ? 58  C   T P     1 
ATOM   10880 O  OP1   . C   F 3 57  ? 204.906 213.017 272.393 1.00 125.61 ? 58  C   T OP1   1 
ATOM   10881 O  OP2   . C   F 3 57  ? 205.588 212.199 270.063 1.00 121.37 ? 58  C   T OP2   1 
ATOM   10882 O  "O5'" . C   F 3 57  ? 207.200 212.084 271.961 1.00 111.04 ? 58  C   T "O5'" 1 
ATOM   10883 C  "C5'" . C   F 3 57  ? 207.560 211.740 273.320 1.00 104.39 ? 58  C   T "C5'" 1 
ATOM   10884 C  "C4'" . C   F 3 57  ? 209.062 211.727 273.456 1.00 99.67  ? 58  C   T "C4'" 1 
ATOM   10885 O  "O4'" . C   F 3 57  ? 209.621 210.582 272.763 1.00 94.05  ? 58  C   T "O4'" 1 
ATOM   10886 C  "C3'" . C   F 3 57  ? 209.791 212.925 272.846 1.00 95.99  ? 58  C   T "C3'" 1 
ATOM   10887 O  "O3'" . C   F 3 57  ? 209.783 214.033 273.731 1.00 100.26 ? 58  C   T "O3'" 1 
ATOM   10888 C  "C2'" . C   F 3 57  ? 211.197 212.356 272.639 1.00 92.00  ? 58  C   T "C2'" 1 
ATOM   10889 O  "O2'" . C   F 3 57  ? 211.963 212.350 273.825 1.00 90.80  ? 58  C   T "O2'" 1 
ATOM   10890 C  "C1'" . C   F 3 57  ? 210.892 210.908 272.241 1.00 89.11  ? 58  C   T "C1'" 1 
ATOM   10891 N  N1    . C   F 3 57  ? 210.868 210.691 270.770 1.00 83.12  ? 58  C   T N1    1 
ATOM   10892 C  C2    . C   F 3 57  ? 212.081 210.587 270.077 1.00 78.98  ? 58  C   T C2    1 
ATOM   10893 O  O2    . C   F 3 57  ? 213.146 210.691 270.705 1.00 76.77  ? 58  C   T O2    1 
ATOM   10894 N  N3    . C   F 3 57  ? 212.060 210.373 268.738 1.00 75.08  ? 58  C   T N3    1 
ATOM   10895 C  C4    . C   F 3 57  ? 210.890 210.264 268.092 1.00 77.29  ? 58  C   T C4    1 
ATOM   10896 N  N4    . C   F 3 57  ? 210.923 210.058 266.783 1.00 74.18  ? 58  C   T N4    1 
ATOM   10897 C  C5    . C   F 3 57  ? 209.649 210.366 268.781 1.00 78.69  ? 58  C   T C5    1 
ATOM   10898 C  C6    . C   F 3 57  ? 209.683 210.575 270.104 1.00 82.01  ? 58  C   T C6    1 
ATOM   10899 P  P     . C   F 3 58  ? 210.008 215.514 273.159 1.00 103.37 ? 59  C   T P     1 
ATOM   10900 O  OP1   . C   F 3 58  ? 209.610 216.502 274.203 1.00 108.56 ? 59  C   T OP1   1 
ATOM   10901 O  OP2   . C   F 3 58  ? 209.375 215.609 271.812 1.00 99.17  ? 59  C   T OP2   1 
ATOM   10902 O  "O5'" . C   F 3 58  ? 211.598 215.562 272.998 1.00 93.13  ? 59  C   T "O5'" 1 
ATOM   10903 C  "C5'" . C   F 3 58  ? 212.155 216.501 272.059 1.00 87.70  ? 59  C   T "C5'" 1 
ATOM   10904 C  "C4'" . C   F 3 58  ? 213.532 216.058 271.640 1.00 82.07  ? 59  C   T "C4'" 1 
ATOM   10905 O  "O4'" . C   F 3 58  ? 213.518 214.673 271.205 1.00 76.83  ? 59  C   T "O4'" 1 
ATOM   10906 C  "C3'" . C   F 3 58  ? 214.093 216.819 270.438 1.00 78.76  ? 59  C   T "C3'" 1 
ATOM   10907 O  "O3'" . C   F 3 58  ? 214.664 218.057 270.822 1.00 78.15  ? 59  C   T "O3'" 1 
ATOM   10908 C  "C2'" . C   F 3 58  ? 215.118 215.829 269.887 1.00 74.74  ? 59  C   T "C2'" 1 
ATOM   10909 O  "O2'" . C   F 3 58  ? 216.315 215.827 270.634 1.00 74.78  ? 59  C   T "O2'" 1 
ATOM   10910 C  "C1'" . C   F 3 58  ? 214.390 214.499 270.106 1.00 72.05  ? 59  C   T "C1'" 1 
ATOM   10911 N  N1    . C   F 3 58  ? 213.583 214.078 268.930 1.00 65.15  ? 59  C   T N1    1 
ATOM   10912 C  C2    . C   F 3 58  ? 214.228 213.592 267.786 1.00 62.45  ? 59  C   T C2    1 
ATOM   10913 O  O2    . C   F 3 58  ? 215.468 213.531 267.763 1.00 62.37  ? 59  C   T O2    1 
ATOM   10914 N  N3    . C   F 3 58  ? 213.479 213.203 266.728 1.00 58.35  ? 59  C   T N3    1 
ATOM   10915 C  C4    . C   F 3 58  ? 212.143 213.276 266.776 1.00 59.00  ? 59  C   T C4    1 
ATOM   10916 N  N4    . C   F 3 58  ? 211.448 212.886 265.716 1.00 59.21  ? 59  C   T N4    1 
ATOM   10917 C  C5    . C   F 3 58  ? 211.474 213.760 267.931 1.00 61.51  ? 59  C   T C5    1 
ATOM   10918 C  C6    . C   F 3 58  ? 212.223 214.145 268.973 1.00 62.55  ? 59  C   T C6    1 
ATOM   10919 P  P     . C   F 3 59  ? 214.006 219.425 270.300 1.00 80.68  ? 60  C   T P     1 
ATOM   10920 O  OP1   . C   F 3 59  ? 214.097 220.454 271.375 1.00 85.96  ? 60  C   T OP1   1 
ATOM   10921 O  OP2   . C   F 3 59  ? 212.670 219.116 269.717 1.00 77.52  ? 60  C   T OP2   1 
ATOM   10922 O  "O5'" . C   F 3 59  ? 214.971 219.858 269.103 1.00 72.28  ? 60  C   T "O5'" 1 
ATOM   10923 C  "C5'" . C   F 3 59  ? 216.396 219.919 269.347 1.00 68.19  ? 60  C   T "C5'" 1 
ATOM   10924 C  "C4'" . C   F 3 59  ? 217.146 219.525 268.099 1.00 63.32  ? 60  C   T "C4'" 1 
ATOM   10925 O  "O4'" . C   F 3 59  ? 216.935 218.122 267.800 1.00 59.01  ? 60  C   T "O4'" 1 
ATOM   10926 C  "C3'" . C   F 3 59  ? 216.723 220.231 266.811 1.00 61.80  ? 60  C   T "C3'" 1 
ATOM   10927 O  "O3'" . C   F 3 59  ? 217.281 221.528 266.703 1.00 63.36  ? 60  C   T "O3'" 1 
ATOM   10928 C  "C2'" . C   F 3 59  ? 217.282 219.270 265.759 1.00 60.31  ? 60  C   T "C2'" 1 
ATOM   10929 O  "O2'" . C   F 3 59  ? 218.676 219.404 265.587 1.00 60.62  ? 60  C   T "O2'" 1 
ATOM   10930 C  "C1'" . C   F 3 59  ? 216.988 217.914 266.405 1.00 55.28  ? 60  C   T "C1'" 1 
ATOM   10931 N  N1    . C   F 3 59  ? 215.699 217.329 265.950 1.00 46.95  ? 60  C   T N1    1 
ATOM   10932 C  C2    . C   F 3 59  ? 215.664 216.676 264.714 1.00 43.55  ? 60  C   T C2    1 
ATOM   10933 O  O2    . C   F 3 59  ? 216.702 216.608 264.037 1.00 42.10  ? 60  C   T O2    1 
ATOM   10934 N  N3    . C   F 3 59  ? 214.501 216.135 264.286 1.00 39.40  ? 60  C   T N3    1 
ATOM   10935 C  C4    . C   F 3 59  ? 213.400 216.219 265.038 1.00 41.13  ? 60  C   T C4    1 
ATOM   10936 N  N4    . C   F 3 59  ? 212.291 215.663 264.567 1.00 39.20  ? 60  C   T N4    1 
ATOM   10937 C  C5    . C   F 3 59  ? 213.416 216.881 266.299 1.00 42.69  ? 60  C   T C5    1 
ATOM   10938 C  C6    . C   F 3 59  ? 214.574 217.418 266.711 1.00 44.38  ? 60  C   T C6    1 
ATOM   10939 P  P     . U   F 3 60  ? 216.477 222.665 265.909 1.00 64.40  ? 61  U   T P     1 
ATOM   10940 O  OP1   . U   F 3 60  ? 217.016 224.006 266.273 1.00 68.79  ? 61  U   T OP1   1 
ATOM   10941 O  OP2   . U   F 3 60  ? 215.018 222.409 266.068 1.00 61.47  ? 61  U   T OP2   1 
ATOM   10942 O  "O5'" . U   F 3 60  ? 216.849 222.363 264.387 1.00 58.08  ? 61  U   T "O5'" 1 
ATOM   10943 C  "C5'" . U   F 3 60  ? 218.243 222.268 264.008 1.00 54.73  ? 61  U   T "C5'" 1 
ATOM   10944 C  "C4'" . U   F 3 60  ? 218.355 221.679 262.623 1.00 51.98  ? 61  U   T "C4'" 1 
ATOM   10945 O  "O4'" . U   F 3 60  ? 217.937 220.290 262.625 1.00 49.76  ? 61  U   T "O4'" 1 
ATOM   10946 C  "C3'" . U   F 3 60  ? 217.469 222.317 261.552 1.00 49.19  ? 61  U   T "C3'" 1 
ATOM   10947 O  "O3'" . U   F 3 60  ? 218.025 223.518 261.044 1.00 49.45  ? 61  U   T "O3'" 1 
ATOM   10948 C  "C2'" . U   F 3 60  ? 217.427 221.207 260.500 1.00 46.99  ? 61  U   T "C2'" 1 
ATOM   10949 O  "O2'" . U   F 3 60  ? 218.609 221.148 259.732 1.00 47.79  ? 61  U   T "O2'" 1 
ATOM   10950 C  "C1'" . U   F 3 60  ? 217.346 219.962 261.382 1.00 46.75  ? 61  U   T "C1'" 1 
ATOM   10951 N  N1    . U   F 3 60  ? 215.959 219.511 261.616 1.00 42.66  ? 61  U   T N1    1 
ATOM   10952 C  C2    . U   F 3 60  ? 215.336 218.799 260.606 1.00 39.39  ? 61  U   T C2    1 
ATOM   10953 O  O2    . U   F 3 60  ? 215.882 218.534 259.546 1.00 41.30  ? 61  U   T O2    1 
ATOM   10954 N  N3    . U   F 3 60  ? 214.052 218.402 260.882 1.00 37.36  ? 61  U   T N3    1 
ATOM   10955 C  C4    . U   F 3 60  ? 213.344 218.639 262.045 1.00 39.20  ? 61  U   T C4    1 
ATOM   10956 O  O4    . U   F 3 60  ? 212.191 218.221 262.154 1.00 38.56  ? 61  U   T O4    1 
ATOM   10957 C  C5    . U   F 3 60  ? 214.057 219.386 263.040 1.00 38.47  ? 61  U   T C5    1 
ATOM   10958 C  C6    . U   F 3 60  ? 215.312 219.785 262.796 1.00 39.89  ? 61  U   T C6    1 
ATOM   10959 P  P     . U   F 3 61  ? 217.062 224.745 260.675 1.00 49.90  ? 62  U   T P     1 
ATOM   10960 O  OP1   . U   F 3 61  ? 217.895 225.965 260.474 1.00 52.39  ? 62  U   T OP1   1 
ATOM   10961 O  OP2   . U   F 3 61  ? 215.943 224.787 261.657 1.00 45.97  ? 62  U   T OP2   1 
ATOM   10962 O  "O5'" . U   F 3 61  ? 216.435 224.300 259.274 1.00 44.38  ? 62  U   T "O5'" 1 
ATOM   10963 C  "C5'" . U   F 3 61  ? 217.320 224.020 258.166 1.00 41.74  ? 62  U   T "C5'" 1 
ATOM   10964 C  "C4'" . U   F 3 61  ? 216.568 223.277 257.089 1.00 40.80  ? 62  U   T "C4'" 1 
ATOM   10965 O  "O4'" . U   F 3 61  ? 216.153 221.972 257.570 1.00 38.57  ? 62  U   T "O4'" 1 
ATOM   10966 C  "C3'" . U   F 3 61  ? 215.260 223.915 256.617 1.00 39.91  ? 62  U   T "C3'" 1 
ATOM   10967 O  "O3'" . U   F 3 61  ? 215.476 224.969 255.695 1.00 40.66  ? 62  U   T "O3'" 1 
ATOM   10968 C  "C2'" . U   F 3 61  ? 214.562 222.710 255.982 1.00 39.40  ? 62  U   T "C2'" 1 
ATOM   10969 O  "O2'" . U   F 3 61  ? 215.082 222.402 254.707 1.00 37.38  ? 62  U   T "O2'" 1 
ATOM   10970 C  "C1'" . U   F 3 61  ? 214.933 221.600 256.965 1.00 37.01  ? 62  U   T "C1'" 1 
ATOM   10971 N  N1    . U   F 3 61  ? 213.912 221.408 258.013 1.00 35.72  ? 62  U   T N1    1 
ATOM   10972 C  C2    . U   F 3 61  ? 212.819 220.628 257.698 1.00 34.50  ? 62  U   T C2    1 
ATOM   10973 O  O2    . U   F 3 61  ? 212.677 220.098 256.606 1.00 36.31  ? 62  U   T O2    1 
ATOM   10974 N  N3    . U   F 3 61  ? 211.897 220.485 258.703 1.00 34.52  ? 62  U   T N3    1 
ATOM   10975 C  C4    . U   F 3 61  ? 211.956 221.034 259.968 1.00 34.68  ? 62  U   T C4    1 
ATOM   10976 O  O4    . U   F 3 61  ? 211.045 220.819 260.768 1.00 36.11  ? 62  U   T O4    1 
ATOM   10977 C  C5    . U   F 3 61  ? 213.113 221.837 260.216 1.00 35.09  ? 62  U   T C5    1 
ATOM   10978 C  C6    . U   F 3 61  ? 214.032 221.989 259.253 1.00 36.64  ? 62  U   T C6    1 
ATOM   10979 P  P     . A   F 3 62  ? 214.481 226.225 255.681 1.00 42.71  ? 63  A   T P     1 
ATOM   10980 O  OP1   . A   F 3 62  ? 215.092 227.284 254.827 1.00 48.04  ? 63  A   T OP1   1 
ATOM   10981 O  OP2   . A   F 3 62  ? 214.123 226.550 257.089 1.00 43.93  ? 63  A   T OP2   1 
ATOM   10982 O  "O5'" . A   F 3 62  ? 213.153 225.663 254.990 1.00 40.87  ? 63  A   T "O5'" 1 
ATOM   10983 C  "C5'" . A   F 3 62  ? 213.231 225.166 253.631 1.00 37.98  ? 63  A   T "C5'" 1 
ATOM   10984 C  "C4'" . A   F 3 62  ? 211.998 224.358 253.307 1.00 36.16  ? 63  A   T "C4'" 1 
ATOM   10985 O  "O4'" . A   F 3 62  ? 211.933 223.189 254.159 1.00 34.03  ? 63  A   T "O4'" 1 
ATOM   10986 C  "C3'" . A   F 3 62  ? 210.647 225.041 253.523 1.00 34.69  ? 63  A   T "C3'" 1 
ATOM   10987 O  "O3'" . A   F 3 62  ? 210.307 225.888 252.441 1.00 36.27  ? 63  A   T "O3'" 1 
ATOM   10988 C  "C2'" . A   F 3 62  ? 209.723 223.826 253.615 1.00 34.12  ? 63  A   T "C2'" 1 
ATOM   10989 O  "O2'" . A   F 3 62  ? 209.410 223.267 252.359 1.00 35.51  ? 63  A   T "O2'" 1 
ATOM   10990 C  "C1'" . A   F 3 62  ? 210.586 222.845 254.404 1.00 33.27  ? 63  A   T "C1'" 1 
ATOM   10991 N  N9    . A   F 3 62  ? 210.336 222.885 255.840 1.00 30.74  ? 63  A   T N9    1 
ATOM   10992 C  C8    . A   F 3 62  ? 211.147 223.406 256.817 1.00 31.21  ? 63  A   T C8    1 
ATOM   10993 N  N7    . A   F 3 62  ? 210.652 223.299 258.022 1.00 31.38  ? 63  A   T N7    1 
ATOM   10994 C  C5    . A   F 3 62  ? 209.431 222.676 257.828 1.00 30.89  ? 63  A   T C5    1 
ATOM   10995 C  C6    . A   F 3 62  ? 208.422 222.286 258.724 1.00 33.27  ? 63  A   T C6    1 
ATOM   10996 N  N6    . A   F 3 62  ? 208.488 222.480 260.038 1.00 35.46  ? 63  A   T N6    1 
ATOM   10997 N  N1    . A   F 3 62  ? 207.326 221.685 258.206 1.00 33.66  ? 63  A   T N1    1 
ATOM   10998 C  C2    . A   F 3 62  ? 207.263 221.496 256.881 1.00 32.21  ? 63  A   T C2    1 
ATOM   10999 N  N3    . A   F 3 62  ? 208.148 221.821 255.946 1.00 30.31  ? 63  A   T N3    1 
ATOM   11000 C  C4    . A   F 3 62  ? 209.222 222.416 256.489 1.00 30.58  ? 63  A   T C4    1 
ATOM   11001 P  P     . U   F 3 63  ? 209.329 227.137 252.665 1.00 36.98  ? 64  U   T P     1 
ATOM   11002 O  OP1   . U   F 3 63  ? 209.361 227.993 251.444 1.00 39.74  ? 64  U   T OP1   1 
ATOM   11003 O  OP2   . U   F 3 63  ? 209.677 227.750 253.976 1.00 39.11  ? 64  U   T OP2   1 
ATOM   11004 O  "O5'" . U   F 3 63  ? 207.888 226.470 252.815 1.00 34.08  ? 64  U   T "O5'" 1 
ATOM   11005 C  "C5'" . U   F 3 63  ? 207.330 225.733 251.707 1.00 33.56  ? 64  U   T "C5'" 1 
ATOM   11006 C  "C4'" . U   F 3 63  ? 205.992 225.157 252.097 1.00 34.19  ? 64  U   T "C4'" 1 
ATOM   11007 O  "O4'" . U   F 3 63  ? 206.164 224.125 253.100 1.00 34.14  ? 64  U   T "O4'" 1 
ATOM   11008 C  "C3'" . U   F 3 63  ? 205.004 226.129 252.742 1.00 33.55  ? 64  U   T "C3'" 1 
ATOM   11009 O  "O3'" . U   F 3 63  ? 204.309 226.899 251.773 1.00 37.85  ? 64  U   T "O3'" 1 
ATOM   11010 C  "C2'" . U   F 3 63  ? 204.069 225.172 253.481 1.00 32.41  ? 64  U   T "C2'" 1 
ATOM   11011 O  "O2'" . U   F 3 63  ? 203.124 224.563 252.629 1.00 31.40  ? 64  U   T "O2'" 1 
ATOM   11012 C  "C1'" . U   F 3 63  ? 205.051 224.111 253.971 1.00 32.72  ? 64  U   T "C1'" 1 
ATOM   11013 N  N1    . U   F 3 63  ? 205.520 224.355 255.350 1.00 32.32  ? 64  U   T N1    1 
ATOM   11014 C  C2    . U   F 3 63  ? 204.679 223.981 256.380 1.00 32.37  ? 64  U   T C2    1 
ATOM   11015 O  O2    . U   F 3 63  ? 203.581 223.479 256.196 1.00 32.33  ? 64  U   T O2    1 
ATOM   11016 N  N3    . U   F 3 63  ? 205.169 224.216 257.634 1.00 32.29  ? 64  U   T N3    1 
ATOM   11017 C  C4    . U   F 3 63  ? 206.388 224.774 257.958 1.00 33.42  ? 64  U   T C4    1 
ATOM   11018 O  O4    . U   F 3 63  ? 206.688 224.927 259.142 1.00 36.93  ? 64  U   T O4    1 
ATOM   11019 C  C5    . U   F 3 63  ? 207.201 225.136 256.839 1.00 33.33  ? 64  U   T C5    1 
ATOM   11020 C  C6    . U   F 3 63  ? 206.749 224.914 255.599 1.00 32.47  ? 64  U   T C6    1 
ATOM   11021 P  P     . U   F 3 64  ? 203.886 228.413 252.092 1.00 34.30  ? 65  U   T P     1 
ATOM   11022 O  OP1   . U   F 3 64  ? 203.542 229.074 250.802 1.00 37.65  ? 65  U   T OP1   1 
ATOM   11023 O  OP2   . U   F 3 64  ? 204.951 229.005 252.946 1.00 33.34  ? 65  U   T OP2   1 
ATOM   11024 O  "O5'" . U   F 3 64  ? 202.588 228.250 253.006 1.00 37.51  ? 65  U   T "O5'" 1 
ATOM   11025 C  "C5'" . U   F 3 64  ? 201.415 227.611 252.448 1.00 38.35  ? 65  U   T "C5'" 1 
ATOM   11026 C  "C4'" . U   F 3 64  ? 200.484 227.203 253.562 1.00 40.40  ? 65  U   T "C4'" 1 
ATOM   11027 O  "O4'" . U   F 3 64  ? 201.140 226.245 254.432 1.00 41.99  ? 65  U   T "O4'" 1 
ATOM   11028 C  "C3'" . U   F 3 64  ? 200.044 228.313 254.521 1.00 42.66  ? 65  U   T "C3'" 1 
ATOM   11029 O  "O3'" . U   F 3 64  ? 198.976 229.084 253.994 1.00 50.16  ? 65  U   T "O3'" 1 
ATOM   11030 C  "C2'" . U   F 3 64  ? 199.615 227.499 255.743 1.00 41.39  ? 65  U   T "C2'" 1 
ATOM   11031 O  "O2'" . U   F 3 64  ? 198.348 226.901 255.566 1.00 42.69  ? 65  U   T "O2'" 1 
ATOM   11032 C  "C1'" . U   F 3 64  ? 200.679 226.404 255.761 1.00 40.36  ? 65  U   T "C1'" 1 
ATOM   11033 N  N1    . U   F 3 64  ? 201.823 226.731 256.633 1.00 36.78  ? 65  U   T N1    1 
ATOM   11034 C  C2    . U   F 3 64  ? 201.675 226.477 257.986 1.00 36.31  ? 65  U   T C2    1 
ATOM   11035 O  O2    . U   F 3 64  ? 200.650 226.010 258.461 1.00 37.05  ? 65  U   T O2    1 
ATOM   11036 N  N3    . U   F 3 64  ? 202.763 226.786 258.761 1.00 34.43  ? 65  U   T N3    1 
ATOM   11037 C  C4    . U   F 3 64  ? 203.962 227.310 258.324 1.00 34.47  ? 65  U   T C4    1 
ATOM   11038 O  O4    . U   F 3 64  ? 204.859 227.537 259.139 1.00 36.53  ? 65  U   T O4    1 
ATOM   11039 C  C5    . U   F 3 64  ? 204.036 227.548 256.912 1.00 34.23  ? 65  U   T C5    1 
ATOM   11040 C  C6    . U   F 3 64  ? 202.987 227.255 256.129 1.00 34.98  ? 65  U   T C6    1 
ATOM   11041 P  P     . U   F 3 65  ? 198.864 230.643 254.358 1.00 55.10  ? 66  U   T P     1 
ATOM   11042 O  OP1   . U   F 3 65  ? 197.947 231.285 253.373 1.00 57.79  ? 66  U   T OP1   1 
ATOM   11043 O  OP2   . U   F 3 65  ? 200.240 231.185 254.540 1.00 50.66  ? 66  U   T OP2   1 
ATOM   11044 O  "O5'" . U   F 3 65  ? 198.183 230.645 255.804 1.00 58.33  ? 66  U   T "O5'" 1 
ATOM   11045 C  "C5'" . U   F 3 65  ? 196.888 230.019 255.978 1.00 61.40  ? 66  U   T "C5'" 1 
ATOM   11046 C  "C4'" . U   F 3 65  ? 196.643 229.765 257.445 1.00 64.84  ? 66  U   T "C4'" 1 
ATOM   11047 O  "O4'" . U   F 3 65  ? 197.638 228.843 257.962 1.00 60.57  ? 66  U   T "O4'" 1 
ATOM   11048 C  "C3'" . U   F 3 65  ? 196.753 230.984 258.366 1.00 69.55  ? 66  U   T "C3'" 1 
ATOM   11049 O  "O3'" . U   F 3 65  ? 195.562 231.756 258.381 1.00 81.33  ? 66  U   T "O3'" 1 
ATOM   11050 C  "C2'" . U   F 3 65  ? 197.028 230.319 259.718 1.00 66.20  ? 66  U   T "C2'" 1 
ATOM   11051 O  "O2'" . U   F 3 65  ? 195.858 229.799 260.314 1.00 66.48  ? 66  U   T "O2'" 1 
ATOM   11052 C  "C1'" . U   F 3 65  ? 197.939 229.159 259.306 1.00 59.94  ? 66  U   T "C1'" 1 
ATOM   11053 N  N1    . U   F 3 65  ? 199.376 229.489 259.417 1.00 50.68  ? 66  U   T N1    1 
ATOM   11054 C  C2    . U   F 3 65  ? 199.976 229.281 260.643 1.00 47.64  ? 66  U   T C2    1 
ATOM   11055 O  O2    . U   F 3 65  ? 199.366 228.839 261.605 1.00 50.52  ? 66  U   T O2    1 
ATOM   11056 N  N3    . U   F 3 65  ? 201.310 229.603 260.705 1.00 45.04  ? 66  U   T N3    1 
ATOM   11057 C  C4    . U   F 3 65  ? 202.088 230.098 259.677 1.00 44.19  ? 66  U   T C4    1 
ATOM   11058 O  O4    . U   F 3 65  ? 203.279 230.339 259.875 1.00 45.36  ? 66  U   T O4    1 
ATOM   11059 C  C5    . U   F 3 65  ? 201.392 230.294 258.440 1.00 43.81  ? 66  U   T C5    1 
ATOM   11060 C  C6    . U   F 3 65  ? 200.090 229.988 258.355 1.00 46.69  ? 66  U   T C6    1 
ATOM   11061 P  P     . A   F 3 66  ? 195.594 233.276 258.900 1.00 95.90  ? 67  A   T P     1 
ATOM   11062 O  OP1   . A   F 3 66  ? 194.321 233.949 258.514 1.00 97.46  ? 67  A   T OP1   1 
ATOM   11063 O  OP2   . A   F 3 66  ? 196.883 233.906 258.489 1.00 91.18  ? 67  A   T OP2   1 
ATOM   11064 O  "O5'" . A   F 3 66  ? 195.608 233.090 260.490 1.00 96.03  ? 67  A   T "O5'" 1 
ATOM   11065 C  "C5'" . A   F 3 66  ? 196.076 234.185 261.318 1.00 98.17  ? 67  A   T "C5'" 1 
ATOM   11066 C  "C4'" . A   F 3 66  ? 196.408 233.674 262.698 1.00 99.42  ? 67  A   T "C4'" 1 
ATOM   11067 O  "O4'" . A   F 3 66  ? 197.254 232.498 262.607 1.00 91.22  ? 67  A   T "O4'" 1 
ATOM   11068 C  "C3'" . A   F 3 66  ? 197.207 234.637 263.578 1.00 103.12 ? 67  A   T "C3'" 1 
ATOM   11069 O  "O3'" . A   F 3 66  ? 196.381 235.594 264.222 1.00 113.95 ? 67  A   T "O3'" 1 
ATOM   11070 C  "C2'" . A   F 3 66  ? 197.859 233.670 264.568 1.00 97.03  ? 67  A   T "C2'" 1 
ATOM   11071 O  "O2'" . A   F 3 66  ? 196.973 233.255 265.583 1.00 97.05  ? 67  A   T "O2'" 1 
ATOM   11072 C  "C1'" . A   F 3 66  ? 198.198 232.489 263.659 1.00 87.93  ? 67  A   T "C1'" 1 
ATOM   11073 N  N9    . A   F 3 66  ? 199.542 232.562 263.095 1.00 76.51  ? 67  A   T N9    1 
ATOM   11074 C  C8    . A   F 3 66  ? 199.893 232.773 261.784 1.00 72.29  ? 67  A   T C8    1 
ATOM   11075 N  N7    . A   F 3 66  ? 201.188 232.796 261.583 1.00 69.33  ? 67  A   T N7    1 
ATOM   11076 C  C5    . A   F 3 66  ? 201.728 232.586 262.842 1.00 69.59  ? 67  A   T C5    1 
ATOM   11077 C  C6    . A   F 3 66  ? 203.056 232.501 263.297 1.00 70.70  ? 67  A   T C6    1 
ATOM   11078 N  N6    . A   F 3 66  ? 204.114 232.624 262.502 1.00 73.00  ? 67  A   T N6    1 
ATOM   11079 N  N1    . A   F 3 66  ? 203.250 232.280 264.619 1.00 72.17  ? 67  A   T N1    1 
ATOM   11080 C  C2    . A   F 3 66  ? 202.179 232.158 265.412 1.00 71.84  ? 67  A   T C2    1 
ATOM   11081 N  N3    . A   F 3 66  ? 200.888 232.219 265.097 1.00 72.22  ? 67  A   T N3    1 
ATOM   11082 C  C4    . A   F 3 66  ? 200.725 232.437 263.782 1.00 71.68  ? 67  A   T C4    1 
ATOM   11083 P  P     . C   F 3 67  ? 196.850 237.126 264.326 1.00 127.10 ? 68  C   T P     1 
ATOM   11084 O  OP1   . C   F 3 67  ? 195.868 237.866 265.168 1.00 131.91 ? 68  C   T OP1   1 
ATOM   11085 O  OP2   . C   F 3 67  ? 197.133 237.630 262.952 1.00 126.79 ? 68  C   T OP2   1 
ATOM   11086 O  "O5'" . C   F 3 67  ? 198.250 237.041 265.098 1.00 131.78 ? 68  C   T "O5'" 1 
ATOM   11087 C  "C5'" . C   F 3 67  ? 198.248 236.889 266.539 1.00 136.77 ? 68  C   T "C5'" 1 
ATOM   11088 C  "C4'" . C   F 3 67  ? 199.657 236.680 267.039 1.00 143.36 ? 68  C   T "C4'" 1 
ATOM   11089 O  "O4'" . C   F 3 67  ? 200.256 235.530 266.384 1.00 137.43 ? 68  C   T "O4'" 1 
ATOM   11090 C  "C3'" . C   F 3 67  ? 200.645 237.820 266.764 1.00 151.89 ? 68  C   T "C3'" 1 
ATOM   11091 O  "O3'" . C   F 3 67  ? 200.533 238.876 267.705 1.00 172.31 ? 68  C   T "O3'" 1 
ATOM   11092 C  "C2'" . C   F 3 67  ? 201.982 237.082 266.875 1.00 146.19 ? 68  C   T "C2'" 1 
ATOM   11093 O  "O2'" . C   F 3 67  ? 202.360 236.834 268.211 1.00 149.45 ? 68  C   T "O2'" 1 
ATOM   11094 C  "C1'" . C   F 3 67  ? 201.639 235.751 266.197 1.00 132.93 ? 68  C   T "C1'" 1 
ATOM   11095 N  N1    . C   F 3 67  ? 201.928 235.773 264.740 1.00 118.49 ? 68  C   T N1    1 
ATOM   11096 C  C2    . C   F 3 67  ? 203.254 235.649 264.309 1.00 113.07 ? 68  C   T C2    1 
ATOM   11097 O  O2    . C   F 3 67  ? 204.162 235.520 265.146 1.00 108.80 ? 68  C   T O2    1 
ATOM   11098 N  N3    . C   F 3 67  ? 203.509 235.673 262.980 1.00 113.90 ? 68  C   T N3    1 
ATOM   11099 C  C4    . C   F 3 67  ? 202.514 235.814 262.095 1.00 117.77 ? 68  C   T C4    1 
ATOM   11100 N  N4    . C   F 3 67  ? 202.828 235.830 260.807 1.00 120.33 ? 68  C   T N4    1 
ATOM   11101 C  C5    . C   F 3 67  ? 201.163 235.942 262.517 1.00 115.19 ? 68  C   T C5    1 
ATOM   11102 C  C6    . C   F 3 67  ? 200.919 235.917 263.834 1.00 114.22 ? 68  C   T C6    1 
ATOM   11103 P  P     . C   F 3 68  ? 200.311 240.385 267.206 1.00 194.30 ? 69  C   T P     1 
ATOM   11104 O  OP1   . C   F 3 68  ? 200.555 241.301 268.357 1.00 194.40 ? 69  C   T OP1   1 
ATOM   11105 O  OP2   . C   F 3 68  ? 199.002 240.455 266.497 1.00 192.43 ? 69  C   T OP2   1 
ATOM   11106 O  "O5'" . C   F 3 68  ? 201.473 240.577 266.123 1.00 213.21 ? 69  C   T "O5'" 1 
ATOM   11107 C  "C5'" . C   F 3 68  ? 202.711 241.225 266.513 1.00 231.06 ? 69  C   T "C5'" 1 
ATOM   11108 C  "C4'" . C   F 3 68  ? 203.692 240.183 266.989 1.00 245.62 ? 69  C   T "C4'" 1 
ATOM   11109 O  "O4'" . C   F 3 68  ? 204.153 239.384 265.869 1.00 244.39 ? 69  C   T "O4'" 1 
ATOM   11110 C  "C3'" . C   F 3 68  ? 204.992 240.717 267.600 1.00 264.35 ? 69  C   T "C3'" 1 
ATOM   11111 O  "O3'" . C   F 3 68  ? 204.822 241.127 268.948 1.00 304.32 ? 69  C   T "O3'" 1 
ATOM   11112 C  "C2'" . C   F 3 68  ? 205.912 239.502 267.462 1.00 257.16 ? 69  C   T "C2'" 1 
ATOM   11113 O  "O2'" . C   F 3 68  ? 205.673 238.521 268.446 1.00 256.12 ? 69  C   T "O2'" 1 
ATOM   11114 C  "C1'" . C   F 3 68  ? 205.481 238.952 266.098 1.00 248.63 ? 69  C   T "C1'" 1 
ATOM   11115 N  N1    . C   F 3 68  ? 206.346 239.419 264.982 1.00 245.52 ? 69  C   T N1    1 
ATOM   11116 C  C2    . C   F 3 68  ? 206.212 238.786 263.744 1.00 243.63 ? 69  C   T C2    1 
ATOM   11117 O  O2    . C   F 3 68  ? 205.391 237.863 263.631 1.00 239.43 ? 69  C   T O2    1 
ATOM   11118 N  N3    . C   F 3 68  ? 206.988 239.190 262.709 1.00 245.06 ? 69  C   T N3    1 
ATOM   11119 C  C4    . C   F 3 68  ? 207.872 240.182 262.871 1.00 246.17 ? 69  C   T C4    1 
ATOM   11120 N  N4    . C   F 3 68  ? 208.604 240.538 261.825 1.00 246.80 ? 69  C   T N4    1 
ATOM   11121 C  C5    . C   F 3 68  ? 208.020 240.843 264.122 1.00 244.63 ? 69  C   T C5    1 
ATOM   11122 C  C6    . C   F 3 68  ? 207.248 240.434 265.139 1.00 245.58 ? 69  C   T C6    1 
ATOM   11123 P  P     . C   F 3 69  ? 205.003 242.673 269.340 1.00 349.19 ? 70  C   T P     1 
ATOM   11124 O  OP1   . C   F 3 69  ? 203.813 243.430 268.856 1.00 344.76 ? 70  C   T OP1   1 
ATOM   11125 O  OP2   . C   F 3 69  ? 206.354 243.096 268.869 1.00 350.44 ? 70  C   T OP2   1 
ATOM   11126 O  "O5'" . C   F 3 69  ? 204.968 242.636 270.939 1.00 392.49 ? 70  C   T "O5'" 1 
ATOM   11127 C  "C5'" . C   F 3 69  ? 206.210 242.766 271.680 1.00 429.80 ? 70  C   T "C5'" 1 
ATOM   11128 C  "C4'" . C   F 3 69  ? 206.653 241.406 272.153 1.00 453.71 ? 70  C   T "C4'" 1 
ATOM   11129 O  "O4'" . C   F 3 69  ? 207.563 240.811 271.188 1.00 462.75 ? 70  C   T "O4'" 1 
ATOM   11130 C  "C3'" . C   F 3 69  ? 207.405 241.379 273.494 1.00 469.14 ? 70  C   T "C3'" 1 
ATOM   11131 O  "O3'" . C   F 3 69  ? 207.120 240.218 274.260 1.00 484.52 ? 70  C   T "O3'" 1 
ATOM   11132 C  "C2'" . C   F 3 69  ? 208.871 241.370 273.052 1.00 469.36 ? 70  C   T "C2'" 1 
ATOM   11133 O  "O2'" . C   F 3 69  ? 209.751 240.826 274.016 1.00 469.73 ? 70  C   T "O2'" 1 
ATOM   11134 C  "C1'" . C   F 3 69  ? 208.770 240.458 271.827 1.00 468.95 ? 70  C   T "C1'" 1 
ATOM   11135 N  N1    . C   F 3 69  ? 209.896 240.623 270.871 1.00 470.99 ? 70  C   T N1    1 
ATOM   11136 C  C2    . C   F 3 69  ? 209.856 239.930 269.656 1.00 473.72 ? 70  C   T C2    1 
ATOM   11137 O  O2    . C   F 3 69  ? 208.880 239.206 269.403 1.00 474.93 ? 70  C   T O2    1 
ATOM   11138 N  N3    . C   F 3 69  ? 210.884 240.074 268.785 1.00 471.65 ? 70  C   T N3    1 
ATOM   11139 C  C4    . C   F 3 69  ? 211.924 240.862 269.088 1.00 470.96 ? 70  C   T C4    1 
ATOM   11140 N  N4    . C   F 3 69  ? 212.902 240.965 268.199 1.00 469.58 ? 70  C   T N4    1 
ATOM   11141 C  C5    . C   F 3 69  ? 211.983 241.568 270.321 1.00 470.90 ? 70  C   T C5    1 
ATOM   11142 C  C6    . C   F 3 69  ? 210.962 241.419 271.175 1.00 470.91 ? 70  C   T C6    1 
ATOM   11143 P  P     . C   F 3 70  ? 205.890 239.243 273.915 1.00 497.19 ? 71  C   T P     1 
ATOM   11144 O  OP1   . C   F 3 70  ? 206.205 238.431 272.706 1.00 498.00 ? 71  C   T OP1   1 
ATOM   11145 O  OP2   . C   F 3 70  ? 204.607 239.999 273.971 1.00 499.08 ? 71  C   T OP2   1 
ATOM   11146 O  "O5'" . C   F 3 70  ? 205.859 238.232 275.153 1.00 508.15 ? 71  C   T "O5'" 1 
ATOM   11147 C  "C5'" . C   F 3 70  ? 207.038 238.106 275.982 1.00 516.23 ? 71  C   T "C5'" 1 
ATOM   11148 C  "C4'" . C   F 3 70  ? 206.699 238.461 277.409 1.00 522.86 ? 71  C   T "C4'" 1 
ATOM   11149 O  "O4'" . C   F 3 70  ? 207.920 238.511 278.195 1.00 526.49 ? 71  C   T "O4'" 1 
ATOM   11150 C  "C3'" . C   F 3 70  ? 206.014 239.818 277.637 1.00 525.79 ? 71  C   T "C3'" 1 
ATOM   11151 O  "O3'" . C   F 3 70  ? 205.089 239.738 278.712 1.00 528.17 ? 71  C   T "O3'" 1 
ATOM   11152 C  "C2'" . C   F 3 70  ? 207.189 240.740 277.977 1.00 527.48 ? 71  C   T "C2'" 1 
ATOM   11153 O  "O2'" . C   F 3 70  ? 206.830 241.857 278.764 1.00 527.76 ? 71  C   T "O2'" 1 
ATOM   11154 C  "C1'" . C   F 3 70  ? 208.065 239.783 278.788 1.00 529.51 ? 71  C   T "C1'" 1 
ATOM   11155 N  N1    . C   F 3 70  ? 209.503 240.151 278.775 1.00 533.20 ? 71  C   T N1    1 
ATOM   11156 C  C2    . C   F 3 70  ? 210.397 239.373 279.518 1.00 535.19 ? 71  C   T C2    1 
ATOM   11157 O  O2    . C   F 3 70  ? 209.963 238.405 280.162 1.00 536.56 ? 71  C   T O2    1 
ATOM   11158 N  N3    . C   F 3 70  ? 211.712 239.701 279.512 1.00 534.70 ? 71  C   T N3    1 
ATOM   11159 C  C4    . C   F 3 70  ? 212.146 240.753 278.805 1.00 535.27 ? 71  C   T C4    1 
ATOM   11160 N  N4    . C   F 3 70  ? 213.442 241.028 278.836 1.00 535.28 ? 71  C   T N4    1 
ATOM   11161 C  C5    . C   F 3 70  ? 211.248 241.553 278.045 1.00 534.63 ? 71  C   T C5    1 
ATOM   11162 C  C6    . C   F 3 70  ? 209.950 241.220 278.056 1.00 534.31 ? 71  C   T C6    1 
HETATM 11163 N  N     . SAM G 4 .   ? 217.402 222.102 247.264 1.00 58.06  ? 501 SAM F N     1 
HETATM 11164 C  CA    . SAM G 4 .   ? 217.650 221.898 245.810 1.00 57.67  ? 501 SAM F CA    1 
HETATM 11165 C  C     . SAM G 4 .   ? 218.065 223.236 245.186 1.00 60.40  ? 501 SAM F C     1 
HETATM 11166 O  O     . SAM G 4 .   ? 217.545 223.543 244.093 1.00 62.85  ? 501 SAM F O     1 
HETATM 11167 O  OXT   . SAM G 4 .   ? 218.870 223.933 245.831 1.00 58.63  ? 501 SAM F OXT   1 
HETATM 11168 C  CB    . SAM G 4 .   ? 216.389 221.359 245.123 1.00 54.30  ? 501 SAM F CB    1 
HETATM 11169 C  CG    . SAM G 4 .   ? 216.646 220.528 243.874 1.00 52.85  ? 501 SAM F CG    1 
HETATM 11170 S  SD    . SAM G 4 .   ? 215.153 220.516 242.818 1.00 52.26  ? 501 SAM F SD    1 
HETATM 11171 C  CE    . SAM G 4 .   ? 214.221 219.168 243.520 1.00 52.01  ? 501 SAM F CE    1 
HETATM 11172 C  "C5'" . SAM G 4 .   ? 215.773 219.771 241.268 1.00 40.46  ? 501 SAM F "C5'" 1 
HETATM 11173 C  "C4'" . SAM G 4 .   ? 215.954 220.847 240.224 1.00 31.62  ? 501 SAM F "C4'" 1 
HETATM 11174 O  "O4'" . SAM G 4 .   ? 214.679 221.189 239.646 1.00 26.78  ? 501 SAM F "O4'" 1 
HETATM 11175 C  "C3'" . SAM G 4 .   ? 216.486 222.141 240.806 1.00 27.50  ? 501 SAM F "C3'" 1 
HETATM 11176 O  "O3'" . SAM G 4 .   ? 217.903 222.064 240.853 1.00 29.41  ? 501 SAM F "O3'" 1 
HETATM 11177 C  "C2'" . SAM G 4 .   ? 215.925 223.189 239.846 1.00 25.17  ? 501 SAM F "C2'" 1 
HETATM 11178 O  "O2'" . SAM G 4 .   ? 216.796 223.331 238.752 1.00 22.51  ? 501 SAM F "O2'" 1 
HETATM 11179 C  "C1'" . SAM G 4 .   ? 214.593 222.580 239.423 1.00 24.25  ? 501 SAM F "C1'" 1 
HETATM 11180 N  N9    . SAM G 4 .   ? 213.438 223.094 240.151 1.00 20.90  ? 501 SAM F N9    1 
HETATM 11181 C  C8    . SAM G 4 .   ? 212.692 222.387 241.054 1.00 18.78  ? 501 SAM F C8    1 
HETATM 11182 N  N7    . SAM G 4 .   ? 211.699 223.068 241.554 1.00 18.05  ? 501 SAM F N7    1 
HETATM 11183 C  C5    . SAM G 4 .   ? 211.787 224.303 240.942 1.00 18.47  ? 501 SAM F C5    1 
HETATM 11184 C  C6    . SAM G 4 .   ? 211.007 225.465 241.068 1.00 17.49  ? 501 SAM F C6    1 
HETATM 11185 N  N6    . SAM G 4 .   ? 209.955 225.554 241.869 1.00 17.23  ? 501 SAM F N6    1 
HETATM 11186 N  N1    . SAM G 4 .   ? 211.352 226.534 240.323 1.00 17.21  ? 501 SAM F N1    1 
HETATM 11187 C  C2    . SAM G 4 .   ? 212.411 226.427 239.518 1.00 16.88  ? 501 SAM F C2    1 
HETATM 11188 N  N3    . SAM G 4 .   ? 213.218 225.385 239.328 1.00 17.48  ? 501 SAM F N3    1 
HETATM 11189 C  C4    . SAM G 4 .   ? 212.860 224.339 240.080 1.00 18.61  ? 501 SAM F C4    1 
HETATM 11190 P  PG    . GTP H 5 .   ? 218.380 231.613 262.598 1.00 253.05 ? 101 GTP T PG    1 
HETATM 11191 O  O1G   . GTP H 5 .   ? 218.722 231.785 264.067 1.00 251.26 ? 101 GTP T O1G   1 
HETATM 11192 O  O2G   . GTP H 5 .   ? 217.180 230.701 262.413 1.00 252.17 ? 101 GTP T O2G   1 
HETATM 11193 O  O3G   . GTP H 5 .   ? 219.574 231.150 261.785 1.00 252.09 ? 101 GTP T O3G   1 
HETATM 11194 O  O3B   . GTP H 5 .   ? 217.994 233.074 262.010 1.00 242.63 ? 101 GTP T O3B   1 
HETATM 11195 P  PB    . GTP H 5 .   ? 217.295 234.318 262.741 1.00 234.79 ? 101 GTP T PB    1 
HETATM 11196 O  O1B   . GTP H 5 .   ? 217.837 234.416 264.112 1.00 234.29 ? 101 GTP T O1B   1 
HETATM 11197 O  O2B   . GTP H 5 .   ? 217.329 235.491 261.845 1.00 235.31 ? 101 GTP T O2B   1 
HETATM 11198 O  O3A   . GTP H 5 .   ? 215.770 233.857 262.901 1.00 224.03 ? 101 GTP T O3A   1 
HETATM 11199 P  PA    . GTP H 5 .   ? 215.104 233.081 264.142 1.00 215.05 ? 101 GTP T PA    1 
HETATM 11200 O  O1A   . GTP H 5 .   ? 213.862 232.410 263.682 1.00 211.85 ? 101 GTP T O1A   1 
HETATM 11201 O  O2A   . GTP H 5 .   ? 216.103 232.201 264.806 1.00 217.05 ? 101 GTP T O2A   1 
HETATM 11202 O  "O5'" . GTP H 5 .   ? 214.677 234.308 265.084 1.00 196.09 ? 101 GTP T "O5'" 1 
HETATM 11203 C  "C5'" . GTP H 5 .   ? 214.919 234.206 266.523 1.00 182.45 ? 101 GTP T "C5'" 1 
HETATM 11204 C  "C4'" . GTP H 5 .   ? 213.658 233.755 267.223 1.00 171.22 ? 101 GTP T "C4'" 1 
HETATM 11205 O  "O4'" . GTP H 5 .   ? 212.559 234.599 266.819 1.00 161.35 ? 101 GTP T "O4'" 1 
HETATM 11206 C  "C3'" . GTP H 5 .   ? 213.250 232.302 266.965 1.00 163.88 ? 101 GTP T "C3'" 1 
HETATM 11207 O  "O3'" . GTP H 5 .   ? 213.294 231.824 268.331 1.00 162.70 ? 101 GTP T "O3'" 1 
HETATM 11208 C  "C2'" . GTP H 5 .   ? 211.901 232.405 266.232 1.00 159.12 ? 101 GTP T "C2'" 1 
HETATM 11209 O  "O2'" . GTP H 5 .   ? 211.066 231.397 266.735 1.00 154.63 ? 101 GTP T "O2'" 1 
HETATM 11210 C  "C1'" . GTP H 5 .   ? 211.405 233.801 266.602 1.00 154.87 ? 101 GTP T "C1'" 1 
HETATM 11211 N  N9    . GTP H 5 .   ? 210.665 234.370 265.482 1.00 145.12 ? 101 GTP T N9    1 
HETATM 11212 C  C8    . GTP H 5 .   ? 211.112 234.475 264.189 1.00 142.71 ? 101 GTP T C8    1 
HETATM 11213 N  N7    . GTP H 5 .   ? 210.232 235.010 263.374 1.00 137.80 ? 101 GTP T N7    1 
HETATM 11214 C  C5    . GTP H 5 .   ? 209.136 235.283 264.180 1.00 132.62 ? 101 GTP T C5    1 
HETATM 11215 C  C6    . GTP H 5 .   ? 207.892 235.868 263.842 1.00 127.19 ? 101 GTP T C6    1 
HETATM 11216 O  O6    . GTP H 5 .   ? 207.578 236.253 262.724 1.00 128.17 ? 101 GTP T O6    1 
HETATM 11217 N  N1    . GTP H 5 .   ? 207.007 236.009 264.920 1.00 126.62 ? 101 GTP T N1    1 
HETATM 11218 C  C2    . GTP H 5 .   ? 207.322 235.595 266.192 1.00 127.83 ? 101 GTP T C2    1 
HETATM 11219 N  N2    . GTP H 5 .   ? 206.395 235.750 267.159 1.00 127.67 ? 101 GTP T N2    1 
HETATM 11220 N  N3    . GTP H 5 .   ? 208.500 235.029 266.504 1.00 131.39 ? 101 GTP T N3    1 
HETATM 11221 C  C4    . GTP H 5 .   ? 209.371 234.901 265.470 1.00 136.43 ? 101 GTP T C4    1 
HETATM 11222 MG MG    . MG  I 6 .   ? 206.976 214.797 244.378 1.00 29.80  ? 102 MG  T MG    1 
HETATM 11223 O  O     . HOH J 7 .   ? 218.980 226.619 245.231 1.00 32.48  ? 601 HOH F O     1 
HETATM 11224 O  O     . HOH J 7 .   ? 214.433 220.370 248.059 1.00 37.46  ? 602 HOH F O     1 
HETATM 11225 O  O     . HOH J 7 .   ? 215.104 224.259 243.096 1.00 20.73  ? 603 HOH F O     1 
HETATM 11226 O  O     . HOH J 7 .   ? 209.907 217.218 244.884 1.00 30.34  ? 604 HOH F O     1 
HETATM 11227 O  O     . HOH J 7 .   ? 207.216 217.753 249.715 1.00 39.12  ? 605 HOH F O     1 
HETATM 11228 O  O     . HOH J 7 .   ? 215.980 224.518 247.042 1.00 38.54  ? 606 HOH F O     1 
HETATM 11229 O  O     . HOH J 7 .   ? 207.256 217.341 243.575 1.00 20.82  ? 607 HOH F O     1 
HETATM 11230 O  O     . HOH J 7 .   ? 208.635 216.902 247.281 1.00 27.26  ? 608 HOH F O     1 
HETATM 11231 O  O     . HOH K 7 .   ? 210.826 216.899 249.500 1.00 35.29  ? 201 HOH T O     1 
# 
