data_9GAV
# 
_entry.id   9GAV 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GAV         pdb_00009gav 10.2210/pdb9gav/pdb 
WWPDB D_1292140602 ?            ?                   
EMDB  EMD-51189    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-15 
2 'Structure model' 1 1 2025-02-12 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 2 'Structure model' em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation.year'           
3 2 'Structure model' '_em_admin.last_update'    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GAV 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-29 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'map of the double stranded parallel helical assembly with 14mer RNA'                                                  
EMD-51186 'other EM volume'      
EMDB 'map of the double stranded parallel helical assembly with 12mer RNA'                                                  
EMD-51185 'other EM volume'      
EMDB 'global map of the double stranded antiparallel helical assembly with 18mer RNA'                                       
EMD-51188 'other EM volume'      
EMDB 'map of the single stranded helical assembly with 12mer RNA'                                                           
EMD-51184 'other EM volume'      
EMDB 'focused map on Strand 2 of the double stranded antiparallel helical assembly with 18mer RNA'                          
EMD-51187 'other EM volume'      
EMDB 'Focused reconstruction on strand 1 of the influenza A RNP-like particle double-stranded assembled with a 18-mer RNA.' 
EMD-51189 'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 thibaut.crepin@ibs.fr           Thibaut Crepin           ? 'principal investigator/group leader' 0000-0003-2663-1794 
3 allison.ballandras-colas@ibs.fr Allison Ballandras-Colas ? 'principal investigator/group leader' 0000-0003-4735-4984 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Chenavier, F.'        1 0000-0002-9486-3944 
'Ruigrok, R.W.H.'      2 0000-0002-8094-6642 
'Schoehn, G.'          3 0000-0002-1459-3201 
'Ballandras-Colas, A.' 4 0000-0003-4735-4984 
'Crepin, T.'           5 0000-0003-2663-1794 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nucleic Acids Res.' 
_citation.journal_id_ASTM           NARHAD 
_citation.journal_id_CSD            0389 
_citation.journal_id_ISSN           1362-4962 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            53 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Influenza a virus antiparallel helical nucleocapsid-like pseudo-atomic structure.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1093/nar/gkae1211 
_citation.pdbx_database_id_PubMed   39673795 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chenavier, F.'        1 0000-0002-9486-3944 
primary 'Zarkadas, E.'         2 0000-0002-9276-9831 
primary 'Freslon, L.L.'        3 ?                   
primary 'Stelfox, A.J.'        4 0000-0003-4553-6565 
primary 'Schoehn, G.'          5 0000-0002-1459-3201 
primary 'Ruigrok, R.W.H.'      6 0000-0002-8094-6642 
primary 'Ballandras-Colas, A.' 7 0000-0003-4735-4984 
primary 'Crepin, T.'           8 0000-0003-2663-1794 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Nucleoprotein                                                                                                  
56150.395 3 ? ? ? ? 
2 polymer     syn 
;RNA (5'-P(UC)9-FAM3')
;
5457.170  3 ? ? ? ? 
3 non-polymer syn '2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2R)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid' 
493.505   2 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Nucleocapsid protein,Protein N' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'   no no 
;HMTDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKT
GGPIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTL
PRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAE
FEDLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMA
CHSAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTF
SVQRNLPFDRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDN
AEEYDNLEHHHHHH
;
;HMTDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKT
GGPIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTL
PRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAE
FEDLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMA
CHSAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTF
SVQRNLPFDRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDN
AEEYDNLEHHHHHH
;
G,B,A ? 
2 polyribonucleotide no no UCUCUCUCUCUCUCUCUC UCUCUCUCUCUCUCUCUC D,E,F ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        
'2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2R)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid' 
_pdbx_entity_nonpoly.comp_id     A1IJK 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   HIS n 
1 2   MET n 
1 3   THR n 
1 4   ASP n 
1 5   GLY n 
1 6   GLU n 
1 7   ARG n 
1 8   GLN n 
1 9   ASN n 
1 10  ALA n 
1 11  THR n 
1 12  GLU n 
1 13  ILE n 
1 14  ARG n 
1 15  ALA n 
1 16  SER n 
1 17  VAL n 
1 18  GLY n 
1 19  LYS n 
1 20  MET n 
1 21  ILE n 
1 22  ASP n 
1 23  GLY n 
1 24  ILE n 
1 25  GLY n 
1 26  ARG n 
1 27  PHE n 
1 28  TYR n 
1 29  ILE n 
1 30  GLN n 
1 31  MET n 
1 32  CYS n 
1 33  THR n 
1 34  GLU n 
1 35  LEU n 
1 36  LYS n 
1 37  LEU n 
1 38  SER n 
1 39  ASP n 
1 40  TYR n 
1 41  GLU n 
1 42  GLY n 
1 43  ARG n 
1 44  LEU n 
1 45  ILE n 
1 46  GLN n 
1 47  ASN n 
1 48  SER n 
1 49  LEU n 
1 50  THR n 
1 51  ILE n 
1 52  GLU n 
1 53  ARG n 
1 54  MET n 
1 55  VAL n 
1 56  LEU n 
1 57  SER n 
1 58  ALA n 
1 59  PHE n 
1 60  ASP n 
1 61  GLU n 
1 62  ARG n 
1 63  ARG n 
1 64  ASN n 
1 65  LYS n 
1 66  TYR n 
1 67  LEU n 
1 68  GLU n 
1 69  GLU n 
1 70  HIS n 
1 71  PRO n 
1 72  SER n 
1 73  ALA n 
1 74  GLY n 
1 75  LYS n 
1 76  ASP n 
1 77  PRO n 
1 78  LYS n 
1 79  LYS n 
1 80  THR n 
1 81  GLY n 
1 82  GLY n 
1 83  PRO n 
1 84  ILE n 
1 85  TYR n 
1 86  ARG n 
1 87  ARG n 
1 88  VAL n 
1 89  ASP n 
1 90  GLY n 
1 91  LYS n 
1 92  TRP n 
1 93  ARG n 
1 94  ARG n 
1 95  GLU n 
1 96  LEU n 
1 97  ILE n 
1 98  LEU n 
1 99  TYR n 
1 100 ASP n 
1 101 LYS n 
1 102 GLU n 
1 103 GLU n 
1 104 ILE n 
1 105 ARG n 
1 106 ARG n 
1 107 ILE n 
1 108 TRP n 
1 109 ARG n 
1 110 GLN n 
1 111 ALA n 
1 112 ASN n 
1 113 ASN n 
1 114 GLY n 
1 115 ASP n 
1 116 ASP n 
1 117 ALA n 
1 118 THR n 
1 119 ALA n 
1 120 GLY n 
1 121 LEU n 
1 122 THR n 
1 123 HIS n 
1 124 MET n 
1 125 MET n 
1 126 ILE n 
1 127 TRP n 
1 128 HIS n 
1 129 SER n 
1 130 ASN n 
1 131 LEU n 
1 132 ASN n 
1 133 ASP n 
1 134 ALA n 
1 135 THR n 
1 136 TYR n 
1 137 GLN n 
1 138 ARG n 
1 139 THR n 
1 140 ARG n 
1 141 ALA n 
1 142 LEU n 
1 143 VAL n 
1 144 ARG n 
1 145 THR n 
1 146 GLY n 
1 147 MET n 
1 148 ASP n 
1 149 PRO n 
1 150 ARG n 
1 151 MET n 
1 152 CYS n 
1 153 SER n 
1 154 LEU n 
1 155 MET n 
1 156 GLN n 
1 157 GLY n 
1 158 SER n 
1 159 THR n 
1 160 LEU n 
1 161 PRO n 
1 162 ARG n 
1 163 ARG n 
1 164 SER n 
1 165 GLY n 
1 166 ALA n 
1 167 ALA n 
1 168 GLY n 
1 169 ALA n 
1 170 ALA n 
1 171 VAL n 
1 172 LYS n 
1 173 GLY n 
1 174 VAL n 
1 175 GLY n 
1 176 THR n 
1 177 MET n 
1 178 VAL n 
1 179 MET n 
1 180 GLU n 
1 181 LEU n 
1 182 ILE n 
1 183 ARG n 
1 184 MET n 
1 185 ILE n 
1 186 LYS n 
1 187 ARG n 
1 188 GLY n 
1 189 ILE n 
1 190 ASN n 
1 191 ASP n 
1 192 ARG n 
1 193 ASN n 
1 194 PHE n 
1 195 TRP n 
1 196 ARG n 
1 197 GLY n 
1 198 GLU n 
1 199 ASN n 
1 200 GLY n 
1 201 ARG n 
1 202 ARG n 
1 203 THR n 
1 204 ARG n 
1 205 ILE n 
1 206 ALA n 
1 207 TYR n 
1 208 GLU n 
1 209 ARG n 
1 210 MET n 
1 211 CYS n 
1 212 ASN n 
1 213 ILE n 
1 214 LEU n 
1 215 LYS n 
1 216 GLY n 
1 217 LYS n 
1 218 PHE n 
1 219 GLN n 
1 220 THR n 
1 221 ALA n 
1 222 ALA n 
1 223 GLN n 
1 224 ARG n 
1 225 THR n 
1 226 MET n 
1 227 VAL n 
1 228 ASP n 
1 229 GLN n 
1 230 VAL n 
1 231 ARG n 
1 232 GLU n 
1 233 SER n 
1 234 ARG n 
1 235 ASN n 
1 236 PRO n 
1 237 GLY n 
1 238 ASN n 
1 239 ALA n 
1 240 GLU n 
1 241 PHE n 
1 242 GLU n 
1 243 ASP n 
1 244 LEU n 
1 245 ILE n 
1 246 PHE n 
1 247 LEU n 
1 248 ALA n 
1 249 ARG n 
1 250 SER n 
1 251 ALA n 
1 252 LEU n 
1 253 ILE n 
1 254 LEU n 
1 255 ARG n 
1 256 GLY n 
1 257 SER n 
1 258 VAL n 
1 259 ALA n 
1 260 HIS n 
1 261 LYS n 
1 262 SER n 
1 263 CYS n 
1 264 LEU n 
1 265 PRO n 
1 266 ALA n 
1 267 CYS n 
1 268 VAL n 
1 269 TYR n 
1 270 GLY n 
1 271 SER n 
1 272 ALA n 
1 273 VAL n 
1 274 ALA n 
1 275 SER n 
1 276 GLY n 
1 277 TYR n 
1 278 ASP n 
1 279 PHE n 
1 280 GLU n 
1 281 ARG n 
1 282 GLU n 
1 283 GLY n 
1 284 TYR n 
1 285 SER n 
1 286 LEU n 
1 287 VAL n 
1 288 GLY n 
1 289 ILE n 
1 290 ASP n 
1 291 PRO n 
1 292 PHE n 
1 293 ARG n 
1 294 LEU n 
1 295 LEU n 
1 296 GLN n 
1 297 ASN n 
1 298 SER n 
1 299 GLN n 
1 300 VAL n 
1 301 TYR n 
1 302 SER n 
1 303 LEU n 
1 304 ILE n 
1 305 ARG n 
1 306 PRO n 
1 307 ASN n 
1 308 GLU n 
1 309 ASN n 
1 310 PRO n 
1 311 ALA n 
1 312 HIS n 
1 313 LYS n 
1 314 SER n 
1 315 GLN n 
1 316 LEU n 
1 317 VAL n 
1 318 TRP n 
1 319 MET n 
1 320 ALA n 
1 321 CYS n 
1 322 HIS n 
1 323 SER n 
1 324 ALA n 
1 325 ALA n 
1 326 PHE n 
1 327 GLU n 
1 328 ASP n 
1 329 LEU n 
1 330 ARG n 
1 331 VAL n 
1 332 SER n 
1 333 SER n 
1 334 PHE n 
1 335 ILE n 
1 336 ARG n 
1 337 GLY n 
1 338 THR n 
1 339 LYS n 
1 340 VAL n 
1 341 VAL n 
1 342 PRO n 
1 343 ARG n 
1 344 GLY n 
1 345 LYS n 
1 346 LEU n 
1 347 SER n 
1 348 THR n 
1 349 ARG n 
1 350 GLY n 
1 351 VAL n 
1 352 GLN n 
1 353 ILE n 
1 354 ALA n 
1 355 SER n 
1 356 ASN n 
1 357 GLU n 
1 358 ASN n 
1 359 MET n 
1 360 GLU n 
1 361 THR n 
1 362 MET n 
1 363 GLU n 
1 364 SER n 
1 365 SER n 
1 366 THR n 
1 367 LEU n 
1 368 GLU n 
1 369 LEU n 
1 370 ARG n 
1 371 SER n 
1 372 ARG n 
1 373 TYR n 
1 374 TRP n 
1 375 ALA n 
1 376 ILE n 
1 377 ARG n 
1 378 THR n 
1 379 ARG n 
1 380 SER n 
1 381 GLY n 
1 382 GLY n 
1 383 ASN n 
1 384 THR n 
1 385 ASN n 
1 386 GLN n 
1 387 GLN n 
1 388 ARG n 
1 389 ALA n 
1 390 SER n 
1 391 SER n 
1 392 GLY n 
1 393 GLN n 
1 394 ILE n 
1 395 SER n 
1 396 ILE n 
1 397 GLN n 
1 398 PRO n 
1 399 THR n 
1 400 PHE n 
1 401 SER n 
1 402 VAL n 
1 403 GLN n 
1 404 ARG n 
1 405 ASN n 
1 406 LEU n 
1 407 PRO n 
1 408 PHE n 
1 409 ASP n 
1 410 ARG n 
1 411 PRO n 
1 412 THR n 
1 413 ILE n 
1 414 MET n 
1 415 ALA n 
1 416 ALA n 
1 417 PHE n 
1 418 THR n 
1 419 GLY n 
1 420 ASN n 
1 421 THR n 
1 422 GLU n 
1 423 GLY n 
1 424 ARG n 
1 425 THR n 
1 426 SER n 
1 427 ASP n 
1 428 MET n 
1 429 ARG n 
1 430 THR n 
1 431 GLU n 
1 432 ILE n 
1 433 ILE n 
1 434 ARG n 
1 435 LEU n 
1 436 MET n 
1 437 GLU n 
1 438 SER n 
1 439 ALA n 
1 440 ARG n 
1 441 PRO n 
1 442 GLU n 
1 443 ASP n 
1 444 VAL n 
1 445 SER n 
1 446 PHE n 
1 447 GLN n 
1 448 GLY n 
1 449 ARG n 
1 450 GLY n 
1 451 VAL n 
1 452 PHE n 
1 453 GLU n 
1 454 LEU n 
1 455 SER n 
1 456 ASP n 
1 457 GLU n 
1 458 LYS n 
1 459 ALA n 
1 460 THR n 
1 461 SER n 
1 462 PRO n 
1 463 ILE n 
1 464 VAL n 
1 465 PRO n 
1 466 SER n 
1 467 PHE n 
1 468 ASP n 
1 469 MET n 
1 470 SER n 
1 471 ASN n 
1 472 GLU n 
1 473 GLY n 
1 474 SER n 
1 475 TYR n 
1 476 PHE n 
1 477 PHE n 
1 478 GLY n 
1 479 ASP n 
1 480 ASN n 
1 481 ALA n 
1 482 GLU n 
1 483 GLU n 
1 484 TYR n 
1 485 ASP n 
1 486 ASN n 
1 487 LEU n 
1 488 GLU n 
1 489 HIS n 
1 490 HIS n 
1 491 HIS n 
1 492 HIS n 
1 493 HIS n 
1 494 HIS n 
2 1   U   n 
2 2   C   n 
2 3   U   n 
2 4   C   n 
2 5   U   n 
2 6   C   n 
2 7   U   n 
2 8   C   n 
2 9   U   n 
2 10  C   n 
2 11  U   n 
2 12  C   n 
2 13  U   n 
2 14  C   n 
2 15  U   n 
2 16  C   n 
2 17  U   n 
2 18  C   n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   494 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 NP 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Influenza A virus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     11320 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              2 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       18 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1IJK non-polymer         . 
'2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2R)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid' ? 'C27 H27 N O8'   
493.505 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
C     'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE" ? 'C9 H14 N3 O8 P' 323.197 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'    181.189 
U     'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE" ? 'C9 H13 N2 O9 P' 324.181 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   HIS 1   13  ?   ?   ?   G . n 
A 1 2   MET 2   14  ?   ?   ?   G . n 
A 1 3   THR 3   15  ?   ?   ?   G . n 
A 1 4   ASP 4   16  ?   ?   ?   G . n 
A 1 5   GLY 5   17  ?   ?   ?   G . n 
A 1 6   GLU 6   18  ?   ?   ?   G . n 
A 1 7   ARG 7   19  ?   ?   ?   G . n 
A 1 8   GLN 8   20  ?   ?   ?   G . n 
A 1 9   ASN 9   21  ?   ?   ?   G . n 
A 1 10  ALA 10  22  ?   ?   ?   G . n 
A 1 11  THR 11  23  ?   ?   ?   G . n 
A 1 12  GLU 12  24  ?   ?   ?   G . n 
A 1 13  ILE 13  25  ?   ?   ?   G . n 
A 1 14  ARG 14  26  ?   ?   ?   G . n 
A 1 15  ALA 15  27  ?   ?   ?   G . n 
A 1 16  SER 16  28  ?   ?   ?   G . n 
A 1 17  VAL 17  29  ?   ?   ?   G . n 
A 1 18  GLY 18  30  ?   ?   ?   G . n 
A 1 19  LYS 19  31  ?   ?   ?   G . n 
A 1 20  MET 20  32  ?   ?   ?   G . n 
A 1 21  ILE 21  33  ?   ?   ?   G . n 
A 1 22  ASP 22  34  ?   ?   ?   G . n 
A 1 23  GLY 23  35  ?   ?   ?   G . n 
A 1 24  ILE 24  36  ?   ?   ?   G . n 
A 1 25  GLY 25  37  ?   ?   ?   G . n 
A 1 26  ARG 26  38  ?   ?   ?   G . n 
A 1 27  PHE 27  39  ?   ?   ?   G . n 
A 1 28  TYR 28  40  ?   ?   ?   G . n 
A 1 29  ILE 29  41  ?   ?   ?   G . n 
A 1 30  GLN 30  42  ?   ?   ?   G . n 
A 1 31  MET 31  43  ?   ?   ?   G . n 
A 1 32  CYS 32  44  ?   ?   ?   G . n 
A 1 33  THR 33  45  ?   ?   ?   G . n 
A 1 34  GLU 34  46  ?   ?   ?   G . n 
A 1 35  LEU 35  47  ?   ?   ?   G . n 
A 1 36  LYS 36  48  ?   ?   ?   G . n 
A 1 37  LEU 37  49  ?   ?   ?   G . n 
A 1 38  SER 38  50  ?   ?   ?   G . n 
A 1 39  ASP 39  51  ?   ?   ?   G . n 
A 1 40  TYR 40  52  ?   ?   ?   G . n 
A 1 41  GLU 41  53  ?   ?   ?   G . n 
A 1 42  GLY 42  54  ?   ?   ?   G . n 
A 1 43  ARG 43  55  ?   ?   ?   G . n 
A 1 44  LEU 44  56  ?   ?   ?   G . n 
A 1 45  ILE 45  57  ?   ?   ?   G . n 
A 1 46  GLN 46  58  ?   ?   ?   G . n 
A 1 47  ASN 47  59  ?   ?   ?   G . n 
A 1 48  SER 48  60  ?   ?   ?   G . n 
A 1 49  LEU 49  61  ?   ?   ?   G . n 
A 1 50  THR 50  62  ?   ?   ?   G . n 
A 1 51  ILE 51  63  ?   ?   ?   G . n 
A 1 52  GLU 52  64  ?   ?   ?   G . n 
A 1 53  ARG 53  65  ?   ?   ?   G . n 
A 1 54  MET 54  66  ?   ?   ?   G . n 
A 1 55  VAL 55  67  ?   ?   ?   G . n 
A 1 56  LEU 56  68  ?   ?   ?   G . n 
A 1 57  SER 57  69  ?   ?   ?   G . n 
A 1 58  ALA 58  70  ?   ?   ?   G . n 
A 1 59  PHE 59  71  ?   ?   ?   G . n 
A 1 60  ASP 60  72  ?   ?   ?   G . n 
A 1 61  GLU 61  73  ?   ?   ?   G . n 
A 1 62  ARG 62  74  ?   ?   ?   G . n 
A 1 63  ARG 63  75  ?   ?   ?   G . n 
A 1 64  ASN 64  76  ?   ?   ?   G . n 
A 1 65  LYS 65  77  ?   ?   ?   G . n 
A 1 66  TYR 66  78  ?   ?   ?   G . n 
A 1 67  LEU 67  79  ?   ?   ?   G . n 
A 1 68  GLU 68  80  ?   ?   ?   G . n 
A 1 69  GLU 69  81  ?   ?   ?   G . n 
A 1 70  HIS 70  82  ?   ?   ?   G . n 
A 1 71  PRO 71  83  ?   ?   ?   G . n 
A 1 72  SER 72  84  ?   ?   ?   G . n 
A 1 73  ALA 73  85  ?   ?   ?   G . n 
A 1 74  GLY 74  86  ?   ?   ?   G . n 
A 1 75  LYS 75  87  ?   ?   ?   G . n 
A 1 76  ASP 76  88  ?   ?   ?   G . n 
A 1 77  PRO 77  89  ?   ?   ?   G . n 
A 1 78  LYS 78  90  ?   ?   ?   G . n 
A 1 79  LYS 79  91  ?   ?   ?   G . n 
A 1 80  THR 80  92  ?   ?   ?   G . n 
A 1 81  GLY 81  93  ?   ?   ?   G . n 
A 1 82  GLY 82  94  ?   ?   ?   G . n 
A 1 83  PRO 83  95  ?   ?   ?   G . n 
A 1 84  ILE 84  96  ?   ?   ?   G . n 
A 1 85  TYR 85  97  ?   ?   ?   G . n 
A 1 86  ARG 86  98  ?   ?   ?   G . n 
A 1 87  ARG 87  99  ?   ?   ?   G . n 
A 1 88  VAL 88  100 ?   ?   ?   G . n 
A 1 89  ASP 89  101 ?   ?   ?   G . n 
A 1 90  GLY 90  102 ?   ?   ?   G . n 
A 1 91  LYS 91  103 ?   ?   ?   G . n 
A 1 92  TRP 92  104 ?   ?   ?   G . n 
A 1 93  ARG 93  105 ?   ?   ?   G . n 
A 1 94  ARG 94  106 ?   ?   ?   G . n 
A 1 95  GLU 95  107 ?   ?   ?   G . n 
A 1 96  LEU 96  108 ?   ?   ?   G . n 
A 1 97  ILE 97  109 ?   ?   ?   G . n 
A 1 98  LEU 98  110 ?   ?   ?   G . n 
A 1 99  TYR 99  111 ?   ?   ?   G . n 
A 1 100 ASP 100 112 ?   ?   ?   G . n 
A 1 101 LYS 101 113 ?   ?   ?   G . n 
A 1 102 GLU 102 114 ?   ?   ?   G . n 
A 1 103 GLU 103 115 ?   ?   ?   G . n 
A 1 104 ILE 104 116 ?   ?   ?   G . n 
A 1 105 ARG 105 117 ?   ?   ?   G . n 
A 1 106 ARG 106 118 ?   ?   ?   G . n 
A 1 107 ILE 107 119 ?   ?   ?   G . n 
A 1 108 TRP 108 120 ?   ?   ?   G . n 
A 1 109 ARG 109 121 ?   ?   ?   G . n 
A 1 110 GLN 110 122 ?   ?   ?   G . n 
A 1 111 ALA 111 123 ?   ?   ?   G . n 
A 1 112 ASN 112 124 ?   ?   ?   G . n 
A 1 113 ASN 113 125 ?   ?   ?   G . n 
A 1 114 GLY 114 126 ?   ?   ?   G . n 
A 1 115 ASP 115 127 ?   ?   ?   G . n 
A 1 116 ASP 116 128 ?   ?   ?   G . n 
A 1 117 ALA 117 129 ?   ?   ?   G . n 
A 1 118 THR 118 130 ?   ?   ?   G . n 
A 1 119 ALA 119 131 ?   ?   ?   G . n 
A 1 120 GLY 120 132 ?   ?   ?   G . n 
A 1 121 LEU 121 133 ?   ?   ?   G . n 
A 1 122 THR 122 134 ?   ?   ?   G . n 
A 1 123 HIS 123 135 ?   ?   ?   G . n 
A 1 124 MET 124 136 ?   ?   ?   G . n 
A 1 125 MET 125 137 ?   ?   ?   G . n 
A 1 126 ILE 126 138 ?   ?   ?   G . n 
A 1 127 TRP 127 139 ?   ?   ?   G . n 
A 1 128 HIS 128 140 ?   ?   ?   G . n 
A 1 129 SER 129 141 ?   ?   ?   G . n 
A 1 130 ASN 130 142 ?   ?   ?   G . n 
A 1 131 LEU 131 143 ?   ?   ?   G . n 
A 1 132 ASN 132 144 ?   ?   ?   G . n 
A 1 133 ASP 133 145 ?   ?   ?   G . n 
A 1 134 ALA 134 146 ?   ?   ?   G . n 
A 1 135 THR 135 147 ?   ?   ?   G . n 
A 1 136 TYR 136 148 ?   ?   ?   G . n 
A 1 137 GLN 137 149 ?   ?   ?   G . n 
A 1 138 ARG 138 150 ?   ?   ?   G . n 
A 1 139 THR 139 151 ?   ?   ?   G . n 
A 1 140 ARG 140 152 ?   ?   ?   G . n 
A 1 141 ALA 141 153 ?   ?   ?   G . n 
A 1 142 LEU 142 154 ?   ?   ?   G . n 
A 1 143 VAL 143 155 ?   ?   ?   G . n 
A 1 144 ARG 144 156 ?   ?   ?   G . n 
A 1 145 THR 145 157 ?   ?   ?   G . n 
A 1 146 GLY 146 158 ?   ?   ?   G . n 
A 1 147 MET 147 159 ?   ?   ?   G . n 
A 1 148 ASP 148 160 ?   ?   ?   G . n 
A 1 149 PRO 149 161 ?   ?   ?   G . n 
A 1 150 ARG 150 162 ?   ?   ?   G . n 
A 1 151 MET 151 163 ?   ?   ?   G . n 
A 1 152 CYS 152 164 ?   ?   ?   G . n 
A 1 153 SER 153 165 ?   ?   ?   G . n 
A 1 154 LEU 154 166 ?   ?   ?   G . n 
A 1 155 MET 155 167 ?   ?   ?   G . n 
A 1 156 GLN 156 168 ?   ?   ?   G . n 
A 1 157 GLY 157 169 ?   ?   ?   G . n 
A 1 158 SER 158 170 ?   ?   ?   G . n 
A 1 159 THR 159 171 ?   ?   ?   G . n 
A 1 160 LEU 160 172 ?   ?   ?   G . n 
A 1 161 PRO 161 173 ?   ?   ?   G . n 
A 1 162 ARG 162 174 ?   ?   ?   G . n 
A 1 163 ARG 163 175 ?   ?   ?   G . n 
A 1 164 SER 164 176 ?   ?   ?   G . n 
A 1 165 GLY 165 177 ?   ?   ?   G . n 
A 1 166 ALA 166 178 ?   ?   ?   G . n 
A 1 167 ALA 167 179 ?   ?   ?   G . n 
A 1 168 GLY 168 180 ?   ?   ?   G . n 
A 1 169 ALA 169 181 ?   ?   ?   G . n 
A 1 170 ALA 170 182 ?   ?   ?   G . n 
A 1 171 VAL 171 183 ?   ?   ?   G . n 
A 1 172 LYS 172 184 ?   ?   ?   G . n 
A 1 173 GLY 173 185 ?   ?   ?   G . n 
A 1 174 VAL 174 186 ?   ?   ?   G . n 
A 1 175 GLY 175 187 ?   ?   ?   G . n 
A 1 176 THR 176 188 ?   ?   ?   G . n 
A 1 177 MET 177 189 ?   ?   ?   G . n 
A 1 178 VAL 178 190 ?   ?   ?   G . n 
A 1 179 MET 179 191 ?   ?   ?   G . n 
A 1 180 GLU 180 192 ?   ?   ?   G . n 
A 1 181 LEU 181 193 ?   ?   ?   G . n 
A 1 182 ILE 182 194 ?   ?   ?   G . n 
A 1 183 ARG 183 195 ?   ?   ?   G . n 
A 1 184 MET 184 196 ?   ?   ?   G . n 
A 1 185 ILE 185 197 ?   ?   ?   G . n 
A 1 186 LYS 186 198 ?   ?   ?   G . n 
A 1 187 ARG 187 199 ?   ?   ?   G . n 
A 1 188 GLY 188 200 ?   ?   ?   G . n 
A 1 189 ILE 189 201 ?   ?   ?   G . n 
A 1 190 ASN 190 202 ?   ?   ?   G . n 
A 1 191 ASP 191 203 ?   ?   ?   G . n 
A 1 192 ARG 192 204 ?   ?   ?   G . n 
A 1 193 ASN 193 205 ?   ?   ?   G . n 
A 1 194 PHE 194 206 ?   ?   ?   G . n 
A 1 195 TRP 195 207 ?   ?   ?   G . n 
A 1 196 ARG 196 208 ?   ?   ?   G . n 
A 1 197 GLY 197 209 ?   ?   ?   G . n 
A 1 198 GLU 198 210 ?   ?   ?   G . n 
A 1 199 ASN 199 211 ?   ?   ?   G . n 
A 1 200 GLY 200 212 ?   ?   ?   G . n 
A 1 201 ARG 201 213 ?   ?   ?   G . n 
A 1 202 ARG 202 214 ?   ?   ?   G . n 
A 1 203 THR 203 215 ?   ?   ?   G . n 
A 1 204 ARG 204 216 ?   ?   ?   G . n 
A 1 205 ILE 205 217 ?   ?   ?   G . n 
A 1 206 ALA 206 218 ?   ?   ?   G . n 
A 1 207 TYR 207 219 ?   ?   ?   G . n 
A 1 208 GLU 208 220 ?   ?   ?   G . n 
A 1 209 ARG 209 221 ?   ?   ?   G . n 
A 1 210 MET 210 222 ?   ?   ?   G . n 
A 1 211 CYS 211 223 ?   ?   ?   G . n 
A 1 212 ASN 212 224 ?   ?   ?   G . n 
A 1 213 ILE 213 225 ?   ?   ?   G . n 
A 1 214 LEU 214 226 ?   ?   ?   G . n 
A 1 215 LYS 215 227 ?   ?   ?   G . n 
A 1 216 GLY 216 228 ?   ?   ?   G . n 
A 1 217 LYS 217 229 ?   ?   ?   G . n 
A 1 218 PHE 218 230 ?   ?   ?   G . n 
A 1 219 GLN 219 231 ?   ?   ?   G . n 
A 1 220 THR 220 232 ?   ?   ?   G . n 
A 1 221 ALA 221 233 ?   ?   ?   G . n 
A 1 222 ALA 222 234 ?   ?   ?   G . n 
A 1 223 GLN 223 235 ?   ?   ?   G . n 
A 1 224 ARG 224 236 ?   ?   ?   G . n 
A 1 225 THR 225 237 ?   ?   ?   G . n 
A 1 226 MET 226 238 ?   ?   ?   G . n 
A 1 227 VAL 227 239 ?   ?   ?   G . n 
A 1 228 ASP 228 240 ?   ?   ?   G . n 
A 1 229 GLN 229 241 ?   ?   ?   G . n 
A 1 230 VAL 230 242 ?   ?   ?   G . n 
A 1 231 ARG 231 243 ?   ?   ?   G . n 
A 1 232 GLU 232 244 ?   ?   ?   G . n 
A 1 233 SER 233 245 ?   ?   ?   G . n 
A 1 234 ARG 234 246 ?   ?   ?   G . n 
A 1 235 ASN 235 247 ?   ?   ?   G . n 
A 1 236 PRO 236 248 ?   ?   ?   G . n 
A 1 237 GLY 237 249 ?   ?   ?   G . n 
A 1 238 ASN 238 250 ?   ?   ?   G . n 
A 1 239 ALA 239 251 ?   ?   ?   G . n 
A 1 240 GLU 240 252 ?   ?   ?   G . n 
A 1 241 PHE 241 253 ?   ?   ?   G . n 
A 1 242 GLU 242 254 ?   ?   ?   G . n 
A 1 243 ASP 243 255 ?   ?   ?   G . n 
A 1 244 LEU 244 256 ?   ?   ?   G . n 
A 1 245 ILE 245 257 ?   ?   ?   G . n 
A 1 246 PHE 246 258 ?   ?   ?   G . n 
A 1 247 LEU 247 259 ?   ?   ?   G . n 
A 1 248 ALA 248 260 ?   ?   ?   G . n 
A 1 249 ARG 249 261 ?   ?   ?   G . n 
A 1 250 SER 250 262 ?   ?   ?   G . n 
A 1 251 ALA 251 263 ?   ?   ?   G . n 
A 1 252 LEU 252 264 ?   ?   ?   G . n 
A 1 253 ILE 253 265 ?   ?   ?   G . n 
A 1 254 LEU 254 266 ?   ?   ?   G . n 
A 1 255 ARG 255 267 ?   ?   ?   G . n 
A 1 256 GLY 256 268 ?   ?   ?   G . n 
A 1 257 SER 257 269 ?   ?   ?   G . n 
A 1 258 VAL 258 270 ?   ?   ?   G . n 
A 1 259 ALA 259 271 ?   ?   ?   G . n 
A 1 260 HIS 260 272 ?   ?   ?   G . n 
A 1 261 LYS 261 273 ?   ?   ?   G . n 
A 1 262 SER 262 274 ?   ?   ?   G . n 
A 1 263 CYS 263 275 ?   ?   ?   G . n 
A 1 264 LEU 264 276 ?   ?   ?   G . n 
A 1 265 PRO 265 277 ?   ?   ?   G . n 
A 1 266 ALA 266 278 ?   ?   ?   G . n 
A 1 267 CYS 267 279 ?   ?   ?   G . n 
A 1 268 VAL 268 280 ?   ?   ?   G . n 
A 1 269 TYR 269 281 ?   ?   ?   G . n 
A 1 270 GLY 270 282 ?   ?   ?   G . n 
A 1 271 SER 271 283 ?   ?   ?   G . n 
A 1 272 ALA 272 284 ?   ?   ?   G . n 
A 1 273 VAL 273 285 ?   ?   ?   G . n 
A 1 274 ALA 274 286 ?   ?   ?   G . n 
A 1 275 SER 275 287 ?   ?   ?   G . n 
A 1 276 GLY 276 288 ?   ?   ?   G . n 
A 1 277 TYR 277 289 ?   ?   ?   G . n 
A 1 278 ASP 278 290 ?   ?   ?   G . n 
A 1 279 PHE 279 291 ?   ?   ?   G . n 
A 1 280 GLU 280 292 ?   ?   ?   G . n 
A 1 281 ARG 281 293 ?   ?   ?   G . n 
A 1 282 GLU 282 294 ?   ?   ?   G . n 
A 1 283 GLY 283 295 ?   ?   ?   G . n 
A 1 284 TYR 284 296 ?   ?   ?   G . n 
A 1 285 SER 285 297 ?   ?   ?   G . n 
A 1 286 LEU 286 298 ?   ?   ?   G . n 
A 1 287 VAL 287 299 ?   ?   ?   G . n 
A 1 288 GLY 288 300 ?   ?   ?   G . n 
A 1 289 ILE 289 301 ?   ?   ?   G . n 
A 1 290 ASP 290 302 ?   ?   ?   G . n 
A 1 291 PRO 291 303 ?   ?   ?   G . n 
A 1 292 PHE 292 304 ?   ?   ?   G . n 
A 1 293 ARG 293 305 ?   ?   ?   G . n 
A 1 294 LEU 294 306 ?   ?   ?   G . n 
A 1 295 LEU 295 307 ?   ?   ?   G . n 
A 1 296 GLN 296 308 ?   ?   ?   G . n 
A 1 297 ASN 297 309 ?   ?   ?   G . n 
A 1 298 SER 298 310 ?   ?   ?   G . n 
A 1 299 GLN 299 311 ?   ?   ?   G . n 
A 1 300 VAL 300 312 ?   ?   ?   G . n 
A 1 301 TYR 301 313 ?   ?   ?   G . n 
A 1 302 SER 302 314 ?   ?   ?   G . n 
A 1 303 LEU 303 315 ?   ?   ?   G . n 
A 1 304 ILE 304 316 ?   ?   ?   G . n 
A 1 305 ARG 305 317 ?   ?   ?   G . n 
A 1 306 PRO 306 318 ?   ?   ?   G . n 
A 1 307 ASN 307 319 ?   ?   ?   G . n 
A 1 308 GLU 308 320 ?   ?   ?   G . n 
A 1 309 ASN 309 321 ?   ?   ?   G . n 
A 1 310 PRO 310 322 ?   ?   ?   G . n 
A 1 311 ALA 311 323 ?   ?   ?   G . n 
A 1 312 HIS 312 324 ?   ?   ?   G . n 
A 1 313 LYS 313 325 ?   ?   ?   G . n 
A 1 314 SER 314 326 ?   ?   ?   G . n 
A 1 315 GLN 315 327 ?   ?   ?   G . n 
A 1 316 LEU 316 328 ?   ?   ?   G . n 
A 1 317 VAL 317 329 ?   ?   ?   G . n 
A 1 318 TRP 318 330 ?   ?   ?   G . n 
A 1 319 MET 319 331 ?   ?   ?   G . n 
A 1 320 ALA 320 332 ?   ?   ?   G . n 
A 1 321 CYS 321 333 ?   ?   ?   G . n 
A 1 322 HIS 322 334 ?   ?   ?   G . n 
A 1 323 SER 323 335 ?   ?   ?   G . n 
A 1 324 ALA 324 336 ?   ?   ?   G . n 
A 1 325 ALA 325 337 ?   ?   ?   G . n 
A 1 326 PHE 326 338 ?   ?   ?   G . n 
A 1 327 GLU 327 339 ?   ?   ?   G . n 
A 1 328 ASP 328 340 ?   ?   ?   G . n 
A 1 329 LEU 329 341 ?   ?   ?   G . n 
A 1 330 ARG 330 342 ?   ?   ?   G . n 
A 1 331 VAL 331 343 ?   ?   ?   G . n 
A 1 332 SER 332 344 ?   ?   ?   G . n 
A 1 333 SER 333 345 ?   ?   ?   G . n 
A 1 334 PHE 334 346 ?   ?   ?   G . n 
A 1 335 ILE 335 347 ?   ?   ?   G . n 
A 1 336 ARG 336 348 ?   ?   ?   G . n 
A 1 337 GLY 337 349 ?   ?   ?   G . n 
A 1 338 THR 338 350 ?   ?   ?   G . n 
A 1 339 LYS 339 351 ?   ?   ?   G . n 
A 1 340 VAL 340 352 ?   ?   ?   G . n 
A 1 341 VAL 341 353 ?   ?   ?   G . n 
A 1 342 PRO 342 354 ?   ?   ?   G . n 
A 1 343 ARG 343 355 ?   ?   ?   G . n 
A 1 344 GLY 344 356 ?   ?   ?   G . n 
A 1 345 LYS 345 357 ?   ?   ?   G . n 
A 1 346 LEU 346 358 ?   ?   ?   G . n 
A 1 347 SER 347 359 ?   ?   ?   G . n 
A 1 348 THR 348 360 ?   ?   ?   G . n 
A 1 349 ARG 349 361 ?   ?   ?   G . n 
A 1 350 GLY 350 362 ?   ?   ?   G . n 
A 1 351 VAL 351 363 ?   ?   ?   G . n 
A 1 352 GLN 352 364 ?   ?   ?   G . n 
A 1 353 ILE 353 365 ?   ?   ?   G . n 
A 1 354 ALA 354 366 ?   ?   ?   G . n 
A 1 355 SER 355 367 ?   ?   ?   G . n 
A 1 356 ASN 356 368 ?   ?   ?   G . n 
A 1 357 GLU 357 369 ?   ?   ?   G . n 
A 1 358 ASN 358 370 ?   ?   ?   G . n 
A 1 359 MET 359 371 ?   ?   ?   G . n 
A 1 360 GLU 360 372 ?   ?   ?   G . n 
A 1 361 THR 361 373 ?   ?   ?   G . n 
A 1 362 MET 362 374 ?   ?   ?   G . n 
A 1 363 GLU 363 375 ?   ?   ?   G . n 
A 1 364 SER 364 376 ?   ?   ?   G . n 
A 1 365 SER 365 377 ?   ?   ?   G . n 
A 1 366 THR 366 378 ?   ?   ?   G . n 
A 1 367 LEU 367 379 ?   ?   ?   G . n 
A 1 368 GLU 368 380 ?   ?   ?   G . n 
A 1 369 LEU 369 381 ?   ?   ?   G . n 
A 1 370 ARG 370 382 ?   ?   ?   G . n 
A 1 371 SER 371 383 ?   ?   ?   G . n 
A 1 372 ARG 372 384 ?   ?   ?   G . n 
A 1 373 TYR 373 385 ?   ?   ?   G . n 
A 1 374 TRP 374 386 ?   ?   ?   G . n 
A 1 375 ALA 375 387 ?   ?   ?   G . n 
A 1 376 ILE 376 388 ?   ?   ?   G . n 
A 1 377 ARG 377 389 ?   ?   ?   G . n 
A 1 378 THR 378 390 ?   ?   ?   G . n 
A 1 379 ARG 379 391 ?   ?   ?   G . n 
A 1 380 SER 380 392 ?   ?   ?   G . n 
A 1 381 GLY 381 393 ?   ?   ?   G . n 
A 1 382 GLY 382 394 ?   ?   ?   G . n 
A 1 383 ASN 383 395 ?   ?   ?   G . n 
A 1 384 THR 384 396 ?   ?   ?   G . n 
A 1 385 ASN 385 397 ?   ?   ?   G . n 
A 1 386 GLN 386 398 ?   ?   ?   G . n 
A 1 387 GLN 387 399 ?   ?   ?   G . n 
A 1 388 ARG 388 400 ?   ?   ?   G . n 
A 1 389 ALA 389 401 ?   ?   ?   G . n 
A 1 390 SER 390 402 ?   ?   ?   G . n 
A 1 391 SER 391 403 ?   ?   ?   G . n 
A 1 392 GLY 392 404 404 GLY GLY G . n 
A 1 393 GLN 393 405 405 GLN GLN G . n 
A 1 394 ILE 394 406 406 ILE ILE G . n 
A 1 395 SER 395 407 407 SER SER G . n 
A 1 396 ILE 396 408 408 ILE ILE G . n 
A 1 397 GLN 397 409 409 GLN GLN G . n 
A 1 398 PRO 398 410 410 PRO PRO G . n 
A 1 399 THR 399 411 411 THR THR G . n 
A 1 400 PHE 400 412 412 PHE PHE G . n 
A 1 401 SER 401 413 413 SER SER G . n 
A 1 402 VAL 402 414 414 VAL VAL G . n 
A 1 403 GLN 403 415 415 GLN GLN G . n 
A 1 404 ARG 404 416 416 ARG ARG G . n 
A 1 405 ASN 405 417 417 ASN ASN G . n 
A 1 406 LEU 406 418 418 LEU LEU G . n 
A 1 407 PRO 407 419 419 PRO PRO G . n 
A 1 408 PHE 408 420 420 PHE PHE G . n 
A 1 409 ASP 409 421 421 ASP ASP G . n 
A 1 410 ARG 410 422 422 ARG ARG G . n 
A 1 411 PRO 411 423 423 PRO PRO G . n 
A 1 412 THR 412 424 424 THR THR G . n 
A 1 413 ILE 413 425 425 ILE ILE G . n 
A 1 414 MET 414 426 426 MET MET G . n 
A 1 415 ALA 415 427 427 ALA ALA G . n 
A 1 416 ALA 416 428 428 ALA ALA G . n 
A 1 417 PHE 417 429 429 PHE PHE G . n 
A 1 418 THR 418 430 ?   ?   ?   G . n 
A 1 419 GLY 419 431 ?   ?   ?   G . n 
A 1 420 ASN 420 432 ?   ?   ?   G . n 
A 1 421 THR 421 433 ?   ?   ?   G . n 
A 1 422 GLU 422 434 ?   ?   ?   G . n 
A 1 423 GLY 423 435 ?   ?   ?   G . n 
A 1 424 ARG 424 436 ?   ?   ?   G . n 
A 1 425 THR 425 437 ?   ?   ?   G . n 
A 1 426 SER 426 438 ?   ?   ?   G . n 
A 1 427 ASP 427 439 ?   ?   ?   G . n 
A 1 428 MET 428 440 ?   ?   ?   G . n 
A 1 429 ARG 429 441 ?   ?   ?   G . n 
A 1 430 THR 430 442 ?   ?   ?   G . n 
A 1 431 GLU 431 443 ?   ?   ?   G . n 
A 1 432 ILE 432 444 ?   ?   ?   G . n 
A 1 433 ILE 433 445 ?   ?   ?   G . n 
A 1 434 ARG 434 446 ?   ?   ?   G . n 
A 1 435 LEU 435 447 ?   ?   ?   G . n 
A 1 436 MET 436 448 ?   ?   ?   G . n 
A 1 437 GLU 437 449 ?   ?   ?   G . n 
A 1 438 SER 438 450 ?   ?   ?   G . n 
A 1 439 ALA 439 451 ?   ?   ?   G . n 
A 1 440 ARG 440 452 ?   ?   ?   G . n 
A 1 441 PRO 441 453 ?   ?   ?   G . n 
A 1 442 GLU 442 454 ?   ?   ?   G . n 
A 1 443 ASP 443 455 ?   ?   ?   G . n 
A 1 444 VAL 444 456 ?   ?   ?   G . n 
A 1 445 SER 445 457 ?   ?   ?   G . n 
A 1 446 PHE 446 458 ?   ?   ?   G . n 
A 1 447 GLN 447 459 ?   ?   ?   G . n 
A 1 448 GLY 448 460 ?   ?   ?   G . n 
A 1 449 ARG 449 461 ?   ?   ?   G . n 
A 1 450 GLY 450 462 ?   ?   ?   G . n 
A 1 451 VAL 451 463 ?   ?   ?   G . n 
A 1 452 PHE 452 464 ?   ?   ?   G . n 
A 1 453 GLU 453 465 ?   ?   ?   G . n 
A 1 454 LEU 454 466 ?   ?   ?   G . n 
A 1 455 SER 455 467 ?   ?   ?   G . n 
A 1 456 ASP 456 468 ?   ?   ?   G . n 
A 1 457 GLU 457 469 ?   ?   ?   G . n 
A 1 458 LYS 458 470 ?   ?   ?   G . n 
A 1 459 ALA 459 471 ?   ?   ?   G . n 
A 1 460 THR 460 472 ?   ?   ?   G . n 
A 1 461 SER 461 473 ?   ?   ?   G . n 
A 1 462 PRO 462 474 ?   ?   ?   G . n 
A 1 463 ILE 463 475 ?   ?   ?   G . n 
A 1 464 VAL 464 476 ?   ?   ?   G . n 
A 1 465 PRO 465 477 ?   ?   ?   G . n 
A 1 466 SER 466 478 ?   ?   ?   G . n 
A 1 467 PHE 467 479 ?   ?   ?   G . n 
A 1 468 ASP 468 480 ?   ?   ?   G . n 
A 1 469 MET 469 481 ?   ?   ?   G . n 
A 1 470 SER 470 482 ?   ?   ?   G . n 
A 1 471 ASN 471 483 ?   ?   ?   G . n 
A 1 472 GLU 472 484 ?   ?   ?   G . n 
A 1 473 GLY 473 485 ?   ?   ?   G . n 
A 1 474 SER 474 486 ?   ?   ?   G . n 
A 1 475 TYR 475 487 ?   ?   ?   G . n 
A 1 476 PHE 476 488 ?   ?   ?   G . n 
A 1 477 PHE 477 489 ?   ?   ?   G . n 
A 1 478 GLY 478 490 ?   ?   ?   G . n 
A 1 479 ASP 479 491 ?   ?   ?   G . n 
A 1 480 ASN 480 492 ?   ?   ?   G . n 
A 1 481 ALA 481 493 ?   ?   ?   G . n 
A 1 482 GLU 482 494 ?   ?   ?   G . n 
A 1 483 GLU 483 495 ?   ?   ?   G . n 
A 1 484 TYR 484 496 ?   ?   ?   G . n 
A 1 485 ASP 485 497 ?   ?   ?   G . n 
A 1 486 ASN 486 498 ?   ?   ?   G . n 
A 1 487 LEU 487 499 ?   ?   ?   G . n 
A 1 488 GLU 488 500 ?   ?   ?   G . n 
A 1 489 HIS 489 501 ?   ?   ?   G . n 
A 1 490 HIS 490 502 ?   ?   ?   G . n 
A 1 491 HIS 491 503 ?   ?   ?   G . n 
A 1 492 HIS 492 504 ?   ?   ?   G . n 
A 1 493 HIS 493 505 ?   ?   ?   G . n 
A 1 494 HIS 494 506 ?   ?   ?   G . n 
B 2 1   U   1   7   ?   ?   ?   D . n 
B 2 2   C   2   8   8   C   C   D . n 
B 2 3   U   3   9   9   U   U   D . n 
B 2 4   C   4   10  10  C   C   D . n 
B 2 5   U   5   11  11  U   U   D . n 
B 2 6   C   6   12  12  C   C   D . n 
B 2 7   U   7   13  13  U   U   D . n 
B 2 8   C   8   14  14  C   C   D . n 
B 2 9   U   9   15  15  U   U   D . n 
B 2 10  C   10  16  16  C   C   D . n 
B 2 11  U   11  17  17  U   U   D . n 
B 2 12  C   12  18  18  C   6FM D . n 
B 2 13  U   13  19  ?   ?   ?   D . n 
B 2 14  C   14  20  ?   ?   ?   D . n 
B 2 15  U   15  21  ?   ?   ?   D . n 
B 2 16  C   16  22  ?   ?   ?   D . n 
B 2 17  U   17  23  ?   ?   ?   D . n 
B 2 18  C   18  24  ?   ?   ?   D . n 
C 2 1   U   1   1   1   U   U   E . n 
C 2 2   C   2   2   2   C   C   E . n 
C 2 3   U   3   3   3   U   U   E . n 
C 2 4   C   4   4   4   C   C   E . n 
C 2 5   U   5   5   5   U   U   E . n 
C 2 6   C   6   6   6   C   C   E . n 
C 2 7   U   7   7   7   U   U   E . n 
C 2 8   C   8   8   8   C   C   E . n 
C 2 9   U   9   9   9   U   U   E . n 
C 2 10  C   10  10  10  C   C   E . n 
C 2 11  U   11  11  11  U   U   E . n 
C 2 12  C   12  12  12  C   C   E . n 
C 2 13  U   13  13  13  U   U   E . n 
C 2 14  C   14  14  14  C   C   E . n 
C 2 15  U   15  15  15  U   U   E . n 
C 2 16  C   16  16  16  C   C   E . n 
C 2 17  U   17  17  17  U   U   E . n 
C 2 18  C   18  18  18  C   6FM E . n 
D 2 1   U   1   1   1   U   U   F . n 
D 2 2   C   2   2   2   C   C   F . n 
D 2 3   U   3   3   3   U   U   F . n 
D 2 4   C   4   4   4   C   C   F . n 
D 2 5   U   5   5   5   U   U   F . n 
D 2 6   C   6   6   6   C   C   F . n 
D 2 7   U   7   7   7   U   U   F . n 
D 2 8   C   8   8   ?   ?   ?   F . n 
D 2 9   U   9   9   ?   ?   ?   F . n 
D 2 10  C   10  10  ?   ?   ?   F . n 
D 2 11  U   11  11  ?   ?   ?   F . n 
D 2 12  C   12  12  ?   ?   ?   F . n 
D 2 13  U   13  13  ?   ?   ?   F . n 
D 2 14  C   14  14  ?   ?   ?   F . n 
D 2 15  U   15  15  ?   ?   ?   F . n 
D 2 16  C   16  16  ?   ?   ?   F . n 
D 2 17  U   17  17  ?   ?   ?   F . n 
D 2 18  C   18  18  ?   ?   ?   F . n 
E 1 1   HIS 1   13  ?   ?   ?   B . n 
E 1 2   MET 2   14  ?   ?   ?   B . n 
E 1 3   THR 3   15  15  THR THR B . n 
E 1 4   ASP 4   16  16  ASP ASP B . n 
E 1 5   GLY 5   17  17  GLY GLY B . n 
E 1 6   GLU 6   18  18  GLU GLU B . n 
E 1 7   ARG 7   19  19  ARG ARG B . n 
E 1 8   GLN 8   20  20  GLN GLN B . n 
E 1 9   ASN 9   21  21  ASN ASN B . n 
E 1 10  ALA 10  22  22  ALA ALA B . n 
E 1 11  THR 11  23  23  THR THR B . n 
E 1 12  GLU 12  24  24  GLU GLU B . n 
E 1 13  ILE 13  25  25  ILE ILE B . n 
E 1 14  ARG 14  26  26  ARG ARG B . n 
E 1 15  ALA 15  27  27  ALA ALA B . n 
E 1 16  SER 16  28  28  SER SER B . n 
E 1 17  VAL 17  29  29  VAL VAL B . n 
E 1 18  GLY 18  30  30  GLY GLY B . n 
E 1 19  LYS 19  31  31  LYS LYS B . n 
E 1 20  MET 20  32  32  MET MET B . n 
E 1 21  ILE 21  33  33  ILE ILE B . n 
E 1 22  ASP 22  34  34  ASP ASP B . n 
E 1 23  GLY 23  35  35  GLY GLY B . n 
E 1 24  ILE 24  36  36  ILE ILE B . n 
E 1 25  GLY 25  37  37  GLY GLY B . n 
E 1 26  ARG 26  38  38  ARG ARG B . n 
E 1 27  PHE 27  39  39  PHE PHE B . n 
E 1 28  TYR 28  40  40  TYR TYR B . n 
E 1 29  ILE 29  41  41  ILE ILE B . n 
E 1 30  GLN 30  42  42  GLN GLN B . n 
E 1 31  MET 31  43  43  MET MET B . n 
E 1 32  CYS 32  44  44  CYS CYS B . n 
E 1 33  THR 33  45  45  THR THR B . n 
E 1 34  GLU 34  46  46  GLU GLU B . n 
E 1 35  LEU 35  47  47  LEU LEU B . n 
E 1 36  LYS 36  48  48  LYS LYS B . n 
E 1 37  LEU 37  49  49  LEU LEU B . n 
E 1 38  SER 38  50  50  SER SER B . n 
E 1 39  ASP 39  51  51  ASP ASP B . n 
E 1 40  TYR 40  52  52  TYR TYR B . n 
E 1 41  GLU 41  53  53  GLU GLU B . n 
E 1 42  GLY 42  54  54  GLY GLY B . n 
E 1 43  ARG 43  55  55  ARG ARG B . n 
E 1 44  LEU 44  56  56  LEU LEU B . n 
E 1 45  ILE 45  57  57  ILE ILE B . n 
E 1 46  GLN 46  58  58  GLN GLN B . n 
E 1 47  ASN 47  59  59  ASN ASN B . n 
E 1 48  SER 48  60  60  SER SER B . n 
E 1 49  LEU 49  61  61  LEU LEU B . n 
E 1 50  THR 50  62  62  THR THR B . n 
E 1 51  ILE 51  63  63  ILE ILE B . n 
E 1 52  GLU 52  64  64  GLU GLU B . n 
E 1 53  ARG 53  65  65  ARG ARG B . n 
E 1 54  MET 54  66  66  MET MET B . n 
E 1 55  VAL 55  67  67  VAL VAL B . n 
E 1 56  LEU 56  68  68  LEU LEU B . n 
E 1 57  SER 57  69  69  SER SER B . n 
E 1 58  ALA 58  70  70  ALA ALA B . n 
E 1 59  PHE 59  71  71  PHE PHE B . n 
E 1 60  ASP 60  72  72  ASP ASP B . n 
E 1 61  GLU 61  73  73  GLU GLU B . n 
E 1 62  ARG 62  74  74  ARG ARG B . n 
E 1 63  ARG 63  75  75  ARG ARG B . n 
E 1 64  ASN 64  76  76  ASN ASN B . n 
E 1 65  LYS 65  77  77  LYS LYS B . n 
E 1 66  TYR 66  78  78  TYR TYR B . n 
E 1 67  LEU 67  79  79  LEU LEU B . n 
E 1 68  GLU 68  80  80  GLU GLU B . n 
E 1 69  GLU 69  81  81  GLU GLU B . n 
E 1 70  HIS 70  82  82  HIS HIS B . n 
E 1 71  PRO 71  83  83  PRO PRO B . n 
E 1 72  SER 72  84  84  SER SER B . n 
E 1 73  ALA 73  85  85  ALA ALA B . n 
E 1 74  GLY 74  86  86  GLY GLY B . n 
E 1 75  LYS 75  87  87  LYS LYS B . n 
E 1 76  ASP 76  88  88  ASP ASP B . n 
E 1 77  PRO 77  89  89  PRO PRO B . n 
E 1 78  LYS 78  90  90  LYS LYS B . n 
E 1 79  LYS 79  91  91  LYS LYS B . n 
E 1 80  THR 80  92  92  THR THR B . n 
E 1 81  GLY 81  93  93  GLY GLY B . n 
E 1 82  GLY 82  94  94  GLY GLY B . n 
E 1 83  PRO 83  95  95  PRO PRO B . n 
E 1 84  ILE 84  96  96  ILE ILE B . n 
E 1 85  TYR 85  97  97  TYR TYR B . n 
E 1 86  ARG 86  98  98  ARG ARG B . n 
E 1 87  ARG 87  99  99  ARG ARG B . n 
E 1 88  VAL 88  100 100 VAL VAL B . n 
E 1 89  ASP 89  101 101 ASP ASP B . n 
E 1 90  GLY 90  102 102 GLY GLY B . n 
E 1 91  LYS 91  103 103 LYS LYS B . n 
E 1 92  TRP 92  104 104 TRP TRP B . n 
E 1 93  ARG 93  105 105 ARG ARG B . n 
E 1 94  ARG 94  106 106 ARG ARG B . n 
E 1 95  GLU 95  107 107 GLU GLU B . n 
E 1 96  LEU 96  108 108 LEU LEU B . n 
E 1 97  ILE 97  109 109 ILE ILE B . n 
E 1 98  LEU 98  110 110 LEU LEU B . n 
E 1 99  TYR 99  111 111 TYR TYR B . n 
E 1 100 ASP 100 112 112 ASP ASP B . n 
E 1 101 LYS 101 113 113 LYS LYS B . n 
E 1 102 GLU 102 114 114 GLU GLU B . n 
E 1 103 GLU 103 115 115 GLU GLU B . n 
E 1 104 ILE 104 116 116 ILE ILE B . n 
E 1 105 ARG 105 117 117 ARG ARG B . n 
E 1 106 ARG 106 118 118 ARG ARG B . n 
E 1 107 ILE 107 119 119 ILE ILE B . n 
E 1 108 TRP 108 120 120 TRP TRP B . n 
E 1 109 ARG 109 121 121 ARG ARG B . n 
E 1 110 GLN 110 122 122 GLN GLN B . n 
E 1 111 ALA 111 123 123 ALA ALA B . n 
E 1 112 ASN 112 124 124 ASN ASN B . n 
E 1 113 ASN 113 125 125 ASN ASN B . n 
E 1 114 GLY 114 126 126 GLY GLY B . n 
E 1 115 ASP 115 127 127 ASP ASP B . n 
E 1 116 ASP 116 128 128 ASP ASP B . n 
E 1 117 ALA 117 129 129 ALA ALA B . n 
E 1 118 THR 118 130 130 THR THR B . n 
E 1 119 ALA 119 131 131 ALA ALA B . n 
E 1 120 GLY 120 132 132 GLY GLY B . n 
E 1 121 LEU 121 133 133 LEU LEU B . n 
E 1 122 THR 122 134 134 THR THR B . n 
E 1 123 HIS 123 135 135 HIS HIS B . n 
E 1 124 MET 124 136 136 MET MET B . n 
E 1 125 MET 125 137 137 MET MET B . n 
E 1 126 ILE 126 138 138 ILE ILE B . n 
E 1 127 TRP 127 139 139 TRP TRP B . n 
E 1 128 HIS 128 140 140 HIS HIS B . n 
E 1 129 SER 129 141 141 SER SER B . n 
E 1 130 ASN 130 142 142 ASN ASN B . n 
E 1 131 LEU 131 143 143 LEU LEU B . n 
E 1 132 ASN 132 144 144 ASN ASN B . n 
E 1 133 ASP 133 145 145 ASP ASP B . n 
E 1 134 ALA 134 146 146 ALA ALA B . n 
E 1 135 THR 135 147 147 THR THR B . n 
E 1 136 TYR 136 148 148 TYR TYR B . n 
E 1 137 GLN 137 149 149 GLN GLN B . n 
E 1 138 ARG 138 150 150 ARG ARG B . n 
E 1 139 THR 139 151 151 THR THR B . n 
E 1 140 ARG 140 152 152 ARG ARG B . n 
E 1 141 ALA 141 153 153 ALA ALA B . n 
E 1 142 LEU 142 154 154 LEU LEU B . n 
E 1 143 VAL 143 155 155 VAL VAL B . n 
E 1 144 ARG 144 156 156 ARG ARG B . n 
E 1 145 THR 145 157 157 THR THR B . n 
E 1 146 GLY 146 158 158 GLY GLY B . n 
E 1 147 MET 147 159 159 MET MET B . n 
E 1 148 ASP 148 160 160 ASP ASP B . n 
E 1 149 PRO 149 161 161 PRO PRO B . n 
E 1 150 ARG 150 162 162 ARG ARG B . n 
E 1 151 MET 151 163 163 MET MET B . n 
E 1 152 CYS 152 164 164 CYS CYS B . n 
E 1 153 SER 153 165 165 SER SER B . n 
E 1 154 LEU 154 166 166 LEU LEU B . n 
E 1 155 MET 155 167 167 MET MET B . n 
E 1 156 GLN 156 168 168 GLN GLN B . n 
E 1 157 GLY 157 169 169 GLY GLY B . n 
E 1 158 SER 158 170 170 SER SER B . n 
E 1 159 THR 159 171 171 THR THR B . n 
E 1 160 LEU 160 172 172 LEU LEU B . n 
E 1 161 PRO 161 173 173 PRO PRO B . n 
E 1 162 ARG 162 174 174 ARG ARG B . n 
E 1 163 ARG 163 175 175 ARG ARG B . n 
E 1 164 SER 164 176 176 SER SER B . n 
E 1 165 GLY 165 177 177 GLY GLY B . n 
E 1 166 ALA 166 178 178 ALA ALA B . n 
E 1 167 ALA 167 179 179 ALA ALA B . n 
E 1 168 GLY 168 180 180 GLY GLY B . n 
E 1 169 ALA 169 181 181 ALA ALA B . n 
E 1 170 ALA 170 182 182 ALA ALA B . n 
E 1 171 VAL 171 183 183 VAL VAL B . n 
E 1 172 LYS 172 184 184 LYS LYS B . n 
E 1 173 GLY 173 185 185 GLY GLY B . n 
E 1 174 VAL 174 186 186 VAL VAL B . n 
E 1 175 GLY 175 187 187 GLY GLY B . n 
E 1 176 THR 176 188 188 THR THR B . n 
E 1 177 MET 177 189 189 MET MET B . n 
E 1 178 VAL 178 190 190 VAL VAL B . n 
E 1 179 MET 179 191 191 MET MET B . n 
E 1 180 GLU 180 192 192 GLU GLU B . n 
E 1 181 LEU 181 193 193 LEU LEU B . n 
E 1 182 ILE 182 194 194 ILE ILE B . n 
E 1 183 ARG 183 195 195 ARG ARG B . n 
E 1 184 MET 184 196 196 MET MET B . n 
E 1 185 ILE 185 197 197 ILE ILE B . n 
E 1 186 LYS 186 198 198 LYS LYS B . n 
E 1 187 ARG 187 199 199 ARG ARG B . n 
E 1 188 GLY 188 200 200 GLY GLY B . n 
E 1 189 ILE 189 201 201 ILE ILE B . n 
E 1 190 ASN 190 202 202 ASN ASN B . n 
E 1 191 ASP 191 203 203 ASP ASP B . n 
E 1 192 ARG 192 204 204 ARG ARG B . n 
E 1 193 ASN 193 205 205 ASN ASN B . n 
E 1 194 PHE 194 206 206 PHE PHE B . n 
E 1 195 TRP 195 207 207 TRP TRP B . n 
E 1 196 ARG 196 208 208 ARG ARG B . n 
E 1 197 GLY 197 209 209 GLY GLY B . n 
E 1 198 GLU 198 210 210 GLU GLU B . n 
E 1 199 ASN 199 211 211 ASN ASN B . n 
E 1 200 GLY 200 212 212 GLY GLY B . n 
E 1 201 ARG 201 213 213 ARG ARG B . n 
E 1 202 ARG 202 214 214 ARG ARG B . n 
E 1 203 THR 203 215 215 THR THR B . n 
E 1 204 ARG 204 216 216 ARG ARG B . n 
E 1 205 ILE 205 217 217 ILE ILE B . n 
E 1 206 ALA 206 218 218 ALA ALA B . n 
E 1 207 TYR 207 219 219 TYR TYR B . n 
E 1 208 GLU 208 220 220 GLU GLU B . n 
E 1 209 ARG 209 221 221 ARG ARG B . n 
E 1 210 MET 210 222 222 MET MET B . n 
E 1 211 CYS 211 223 223 CYS CYS B . n 
E 1 212 ASN 212 224 224 ASN ASN B . n 
E 1 213 ILE 213 225 225 ILE ILE B . n 
E 1 214 LEU 214 226 226 LEU LEU B . n 
E 1 215 LYS 215 227 227 LYS LYS B . n 
E 1 216 GLY 216 228 228 GLY GLY B . n 
E 1 217 LYS 217 229 229 LYS LYS B . n 
E 1 218 PHE 218 230 230 PHE PHE B . n 
E 1 219 GLN 219 231 231 GLN GLN B . n 
E 1 220 THR 220 232 232 THR THR B . n 
E 1 221 ALA 221 233 233 ALA ALA B . n 
E 1 222 ALA 222 234 234 ALA ALA B . n 
E 1 223 GLN 223 235 235 GLN GLN B . n 
E 1 224 ARG 224 236 236 ARG ARG B . n 
E 1 225 THR 225 237 237 THR THR B . n 
E 1 226 MET 226 238 238 MET MET B . n 
E 1 227 VAL 227 239 239 VAL VAL B . n 
E 1 228 ASP 228 240 240 ASP ASP B . n 
E 1 229 GLN 229 241 241 GLN GLN B . n 
E 1 230 VAL 230 242 242 VAL VAL B . n 
E 1 231 ARG 231 243 243 ARG ARG B . n 
E 1 232 GLU 232 244 244 GLU GLU B . n 
E 1 233 SER 233 245 245 SER SER B . n 
E 1 234 ARG 234 246 246 ARG ARG B . n 
E 1 235 ASN 235 247 247 ASN ASN B . n 
E 1 236 PRO 236 248 248 PRO PRO B . n 
E 1 237 GLY 237 249 249 GLY GLY B . n 
E 1 238 ASN 238 250 250 ASN ASN B . n 
E 1 239 ALA 239 251 251 ALA ALA B . n 
E 1 240 GLU 240 252 252 GLU GLU B . n 
E 1 241 PHE 241 253 253 PHE PHE B . n 
E 1 242 GLU 242 254 254 GLU GLU B . n 
E 1 243 ASP 243 255 255 ASP ASP B . n 
E 1 244 LEU 244 256 256 LEU LEU B . n 
E 1 245 ILE 245 257 257 ILE ILE B . n 
E 1 246 PHE 246 258 258 PHE PHE B . n 
E 1 247 LEU 247 259 259 LEU LEU B . n 
E 1 248 ALA 248 260 260 ALA ALA B . n 
E 1 249 ARG 249 261 261 ARG ARG B . n 
E 1 250 SER 250 262 262 SER SER B . n 
E 1 251 ALA 251 263 263 ALA ALA B . n 
E 1 252 LEU 252 264 264 LEU LEU B . n 
E 1 253 ILE 253 265 265 ILE ILE B . n 
E 1 254 LEU 254 266 266 LEU LEU B . n 
E 1 255 ARG 255 267 267 ARG ARG B . n 
E 1 256 GLY 256 268 268 GLY GLY B . n 
E 1 257 SER 257 269 269 SER SER B . n 
E 1 258 VAL 258 270 270 VAL VAL B . n 
E 1 259 ALA 259 271 271 ALA ALA B . n 
E 1 260 HIS 260 272 272 HIS HIS B . n 
E 1 261 LYS 261 273 273 LYS LYS B . n 
E 1 262 SER 262 274 274 SER SER B . n 
E 1 263 CYS 263 275 275 CYS CYS B . n 
E 1 264 LEU 264 276 276 LEU LEU B . n 
E 1 265 PRO 265 277 277 PRO PRO B . n 
E 1 266 ALA 266 278 278 ALA ALA B . n 
E 1 267 CYS 267 279 279 CYS CYS B . n 
E 1 268 VAL 268 280 280 VAL VAL B . n 
E 1 269 TYR 269 281 281 TYR TYR B . n 
E 1 270 GLY 270 282 282 GLY GLY B . n 
E 1 271 SER 271 283 283 SER SER B . n 
E 1 272 ALA 272 284 284 ALA ALA B . n 
E 1 273 VAL 273 285 285 VAL VAL B . n 
E 1 274 ALA 274 286 286 ALA ALA B . n 
E 1 275 SER 275 287 287 SER SER B . n 
E 1 276 GLY 276 288 288 GLY GLY B . n 
E 1 277 TYR 277 289 289 TYR TYR B . n 
E 1 278 ASP 278 290 290 ASP ASP B . n 
E 1 279 PHE 279 291 291 PHE PHE B . n 
E 1 280 GLU 280 292 292 GLU GLU B . n 
E 1 281 ARG 281 293 293 ARG ARG B . n 
E 1 282 GLU 282 294 294 GLU GLU B . n 
E 1 283 GLY 283 295 295 GLY GLY B . n 
E 1 284 TYR 284 296 296 TYR TYR B . n 
E 1 285 SER 285 297 297 SER SER B . n 
E 1 286 LEU 286 298 298 LEU LEU B . n 
E 1 287 VAL 287 299 299 VAL VAL B . n 
E 1 288 GLY 288 300 300 GLY GLY B . n 
E 1 289 ILE 289 301 301 ILE ILE B . n 
E 1 290 ASP 290 302 302 ASP ASP B . n 
E 1 291 PRO 291 303 303 PRO PRO B . n 
E 1 292 PHE 292 304 304 PHE PHE B . n 
E 1 293 ARG 293 305 305 ARG ARG B . n 
E 1 294 LEU 294 306 306 LEU LEU B . n 
E 1 295 LEU 295 307 307 LEU LEU B . n 
E 1 296 GLN 296 308 308 GLN GLN B . n 
E 1 297 ASN 297 309 309 ASN ASN B . n 
E 1 298 SER 298 310 310 SER SER B . n 
E 1 299 GLN 299 311 311 GLN GLN B . n 
E 1 300 VAL 300 312 312 VAL VAL B . n 
E 1 301 TYR 301 313 313 TYR TYR B . n 
E 1 302 SER 302 314 314 SER SER B . n 
E 1 303 LEU 303 315 315 LEU LEU B . n 
E 1 304 ILE 304 316 316 ILE ILE B . n 
E 1 305 ARG 305 317 317 ARG ARG B . n 
E 1 306 PRO 306 318 318 PRO PRO B . n 
E 1 307 ASN 307 319 319 ASN ASN B . n 
E 1 308 GLU 308 320 320 GLU GLU B . n 
E 1 309 ASN 309 321 321 ASN ASN B . n 
E 1 310 PRO 310 322 322 PRO PRO B . n 
E 1 311 ALA 311 323 323 ALA ALA B . n 
E 1 312 HIS 312 324 324 HIS HIS B . n 
E 1 313 LYS 313 325 325 LYS LYS B . n 
E 1 314 SER 314 326 326 SER SER B . n 
E 1 315 GLN 315 327 327 GLN GLN B . n 
E 1 316 LEU 316 328 328 LEU LEU B . n 
E 1 317 VAL 317 329 329 VAL VAL B . n 
E 1 318 TRP 318 330 330 TRP TRP B . n 
E 1 319 MET 319 331 331 MET MET B . n 
E 1 320 ALA 320 332 332 ALA ALA B . n 
E 1 321 CYS 321 333 333 CYS CYS B . n 
E 1 322 HIS 322 334 334 HIS HIS B . n 
E 1 323 SER 323 335 335 SER SER B . n 
E 1 324 ALA 324 336 336 ALA ALA B . n 
E 1 325 ALA 325 337 337 ALA ALA B . n 
E 1 326 PHE 326 338 338 PHE PHE B . n 
E 1 327 GLU 327 339 339 GLU GLU B . n 
E 1 328 ASP 328 340 340 ASP ASP B . n 
E 1 329 LEU 329 341 341 LEU LEU B . n 
E 1 330 ARG 330 342 342 ARG ARG B . n 
E 1 331 VAL 331 343 343 VAL VAL B . n 
E 1 332 SER 332 344 344 SER SER B . n 
E 1 333 SER 333 345 345 SER SER B . n 
E 1 334 PHE 334 346 346 PHE PHE B . n 
E 1 335 ILE 335 347 347 ILE ILE B . n 
E 1 336 ARG 336 348 348 ARG ARG B . n 
E 1 337 GLY 337 349 349 GLY GLY B . n 
E 1 338 THR 338 350 350 THR THR B . n 
E 1 339 LYS 339 351 351 LYS LYS B . n 
E 1 340 VAL 340 352 352 VAL VAL B . n 
E 1 341 VAL 341 353 353 VAL VAL B . n 
E 1 342 PRO 342 354 354 PRO PRO B . n 
E 1 343 ARG 343 355 355 ARG ARG B . n 
E 1 344 GLY 344 356 356 GLY GLY B . n 
E 1 345 LYS 345 357 357 LYS LYS B . n 
E 1 346 LEU 346 358 358 LEU LEU B . n 
E 1 347 SER 347 359 359 SER SER B . n 
E 1 348 THR 348 360 360 THR THR B . n 
E 1 349 ARG 349 361 361 ARG ARG B . n 
E 1 350 GLY 350 362 362 GLY GLY B . n 
E 1 351 VAL 351 363 363 VAL VAL B . n 
E 1 352 GLN 352 364 364 GLN GLN B . n 
E 1 353 ILE 353 365 365 ILE ILE B . n 
E 1 354 ALA 354 366 366 ALA ALA B . n 
E 1 355 SER 355 367 367 SER SER B . n 
E 1 356 ASN 356 368 368 ASN ASN B . n 
E 1 357 GLU 357 369 369 GLU GLU B . n 
E 1 358 ASN 358 370 370 ASN ASN B . n 
E 1 359 MET 359 371 371 MET MET B . n 
E 1 360 GLU 360 372 372 GLU GLU B . n 
E 1 361 THR 361 373 373 THR THR B . n 
E 1 362 MET 362 374 374 MET MET B . n 
E 1 363 GLU 363 375 375 GLU GLU B . n 
E 1 364 SER 364 376 376 SER SER B . n 
E 1 365 SER 365 377 377 SER SER B . n 
E 1 366 THR 366 378 378 THR THR B . n 
E 1 367 LEU 367 379 379 LEU LEU B . n 
E 1 368 GLU 368 380 380 GLU GLU B . n 
E 1 369 LEU 369 381 381 LEU LEU B . n 
E 1 370 ARG 370 382 382 ARG ARG B . n 
E 1 371 SER 371 383 383 SER SER B . n 
E 1 372 ARG 372 384 384 ARG ARG B . n 
E 1 373 TYR 373 385 385 TYR TYR B . n 
E 1 374 TRP 374 386 386 TRP TRP B . n 
E 1 375 ALA 375 387 387 ALA ALA B . n 
E 1 376 ILE 376 388 388 ILE ILE B . n 
E 1 377 ARG 377 389 389 ARG ARG B . n 
E 1 378 THR 378 390 390 THR THR B . n 
E 1 379 ARG 379 391 391 ARG ARG B . n 
E 1 380 SER 380 392 392 SER SER B . n 
E 1 381 GLY 381 393 393 GLY GLY B . n 
E 1 382 GLY 382 394 394 GLY GLY B . n 
E 1 383 ASN 383 395 395 ASN ASN B . n 
E 1 384 THR 384 396 ?   ?   ?   B . n 
E 1 385 ASN 385 397 ?   ?   ?   B . n 
E 1 386 GLN 386 398 ?   ?   ?   B . n 
E 1 387 GLN 387 399 ?   ?   ?   B . n 
E 1 388 ARG 388 400 ?   ?   ?   B . n 
E 1 389 ALA 389 401 ?   ?   ?   B . n 
E 1 390 SER 390 402 ?   ?   ?   B . n 
E 1 391 SER 391 403 ?   ?   ?   B . n 
E 1 392 GLY 392 404 404 GLY GLY B . n 
E 1 393 GLN 393 405 405 GLN GLN B . n 
E 1 394 ILE 394 406 406 ILE ILE B . n 
E 1 395 SER 395 407 407 SER SER B . n 
E 1 396 ILE 396 408 408 ILE ILE B . n 
E 1 397 GLN 397 409 409 GLN GLN B . n 
E 1 398 PRO 398 410 410 PRO PRO B . n 
E 1 399 THR 399 411 411 THR THR B . n 
E 1 400 PHE 400 412 412 PHE PHE B . n 
E 1 401 SER 401 413 413 SER SER B . n 
E 1 402 VAL 402 414 414 VAL VAL B . n 
E 1 403 GLN 403 415 415 GLN GLN B . n 
E 1 404 ARG 404 416 416 ARG ARG B . n 
E 1 405 ASN 405 417 417 ASN ASN B . n 
E 1 406 LEU 406 418 418 LEU LEU B . n 
E 1 407 PRO 407 419 419 PRO PRO B . n 
E 1 408 PHE 408 420 420 PHE PHE B . n 
E 1 409 ASP 409 421 421 ASP ASP B . n 
E 1 410 ARG 410 422 422 ARG ARG B . n 
E 1 411 PRO 411 423 423 PRO PRO B . n 
E 1 412 THR 412 424 424 THR THR B . n 
E 1 413 ILE 413 425 425 ILE ILE B . n 
E 1 414 MET 414 426 426 MET MET B . n 
E 1 415 ALA 415 427 427 ALA ALA B . n 
E 1 416 ALA 416 428 428 ALA ALA B . n 
E 1 417 PHE 417 429 429 PHE PHE B . n 
E 1 418 THR 418 430 ?   ?   ?   B . n 
E 1 419 GLY 419 431 ?   ?   ?   B . n 
E 1 420 ASN 420 432 ?   ?   ?   B . n 
E 1 421 THR 421 433 ?   ?   ?   B . n 
E 1 422 GLU 422 434 ?   ?   ?   B . n 
E 1 423 GLY 423 435 ?   ?   ?   B . n 
E 1 424 ARG 424 436 ?   ?   ?   B . n 
E 1 425 THR 425 437 ?   ?   ?   B . n 
E 1 426 SER 426 438 ?   ?   ?   B . n 
E 1 427 ASP 427 439 ?   ?   ?   B . n 
E 1 428 MET 428 440 440 MET MET B . n 
E 1 429 ARG 429 441 441 ARG ARG B . n 
E 1 430 THR 430 442 442 THR THR B . n 
E 1 431 GLU 431 443 443 GLU GLU B . n 
E 1 432 ILE 432 444 444 ILE ILE B . n 
E 1 433 ILE 433 445 445 ILE ILE B . n 
E 1 434 ARG 434 446 446 ARG ARG B . n 
E 1 435 LEU 435 447 447 LEU LEU B . n 
E 1 436 MET 436 448 448 MET MET B . n 
E 1 437 GLU 437 449 449 GLU GLU B . n 
E 1 438 SER 438 450 450 SER SER B . n 
E 1 439 ALA 439 451 451 ALA ALA B . n 
E 1 440 ARG 440 452 452 ARG ARG B . n 
E 1 441 PRO 441 453 453 PRO PRO B . n 
E 1 442 GLU 442 454 454 GLU GLU B . n 
E 1 443 ASP 443 455 455 ASP ASP B . n 
E 1 444 VAL 444 456 456 VAL VAL B . n 
E 1 445 SER 445 457 457 SER SER B . n 
E 1 446 PHE 446 458 458 PHE PHE B . n 
E 1 447 GLN 447 459 459 GLN GLN B . n 
E 1 448 GLY 448 460 460 GLY GLY B . n 
E 1 449 ARG 449 461 461 ARG ARG B . n 
E 1 450 GLY 450 462 462 GLY GLY B . n 
E 1 451 VAL 451 463 463 VAL VAL B . n 
E 1 452 PHE 452 464 464 PHE PHE B . n 
E 1 453 GLU 453 465 465 GLU GLU B . n 
E 1 454 LEU 454 466 466 LEU LEU B . n 
E 1 455 SER 455 467 467 SER SER B . n 
E 1 456 ASP 456 468 468 ASP ASP B . n 
E 1 457 GLU 457 469 469 GLU GLU B . n 
E 1 458 LYS 458 470 470 LYS LYS B . n 
E 1 459 ALA 459 471 471 ALA ALA B . n 
E 1 460 THR 460 472 472 THR THR B . n 
E 1 461 SER 461 473 473 SER SER B . n 
E 1 462 PRO 462 474 474 PRO PRO B . n 
E 1 463 ILE 463 475 475 ILE ILE B . n 
E 1 464 VAL 464 476 476 VAL VAL B . n 
E 1 465 PRO 465 477 477 PRO PRO B . n 
E 1 466 SER 466 478 478 SER SER B . n 
E 1 467 PHE 467 479 479 PHE PHE B . n 
E 1 468 ASP 468 480 ?   ?   ?   B . n 
E 1 469 MET 469 481 ?   ?   ?   B . n 
E 1 470 SER 470 482 ?   ?   ?   B . n 
E 1 471 ASN 471 483 ?   ?   ?   B . n 
E 1 472 GLU 472 484 484 GLU GLU B . n 
E 1 473 GLY 473 485 485 GLY GLY B . n 
E 1 474 SER 474 486 486 SER SER B . n 
E 1 475 TYR 475 487 487 TYR TYR B . n 
E 1 476 PHE 476 488 488 PHE PHE B . n 
E 1 477 PHE 477 489 489 PHE PHE B . n 
E 1 478 GLY 478 490 490 GLY GLY B . n 
E 1 479 ASP 479 491 ?   ?   ?   B . n 
E 1 480 ASN 480 492 ?   ?   ?   B . n 
E 1 481 ALA 481 493 ?   ?   ?   B . n 
E 1 482 GLU 482 494 ?   ?   ?   B . n 
E 1 483 GLU 483 495 ?   ?   ?   B . n 
E 1 484 TYR 484 496 ?   ?   ?   B . n 
E 1 485 ASP 485 497 ?   ?   ?   B . n 
E 1 486 ASN 486 498 ?   ?   ?   B . n 
E 1 487 LEU 487 499 ?   ?   ?   B . n 
E 1 488 GLU 488 500 ?   ?   ?   B . n 
E 1 489 HIS 489 501 ?   ?   ?   B . n 
E 1 490 HIS 490 502 ?   ?   ?   B . n 
E 1 491 HIS 491 503 ?   ?   ?   B . n 
E 1 492 HIS 492 504 ?   ?   ?   B . n 
E 1 493 HIS 493 505 ?   ?   ?   B . n 
E 1 494 HIS 494 506 ?   ?   ?   B . n 
F 1 1   HIS 1   13  ?   ?   ?   A . n 
F 1 2   MET 2   14  ?   ?   ?   A . n 
F 1 3   THR 3   15  15  THR THR A . n 
F 1 4   ASP 4   16  16  ASP ASP A . n 
F 1 5   GLY 5   17  17  GLY GLY A . n 
F 1 6   GLU 6   18  18  GLU GLU A . n 
F 1 7   ARG 7   19  19  ARG ARG A . n 
F 1 8   GLN 8   20  20  GLN GLN A . n 
F 1 9   ASN 9   21  21  ASN ASN A . n 
F 1 10  ALA 10  22  22  ALA ALA A . n 
F 1 11  THR 11  23  23  THR THR A . n 
F 1 12  GLU 12  24  24  GLU GLU A . n 
F 1 13  ILE 13  25  25  ILE ILE A . n 
F 1 14  ARG 14  26  26  ARG ARG A . n 
F 1 15  ALA 15  27  27  ALA ALA A . n 
F 1 16  SER 16  28  28  SER SER A . n 
F 1 17  VAL 17  29  29  VAL VAL A . n 
F 1 18  GLY 18  30  30  GLY GLY A . n 
F 1 19  LYS 19  31  31  LYS LYS A . n 
F 1 20  MET 20  32  32  MET MET A . n 
F 1 21  ILE 21  33  33  ILE ILE A . n 
F 1 22  ASP 22  34  34  ASP ASP A . n 
F 1 23  GLY 23  35  35  GLY GLY A . n 
F 1 24  ILE 24  36  36  ILE ILE A . n 
F 1 25  GLY 25  37  37  GLY GLY A . n 
F 1 26  ARG 26  38  38  ARG ARG A . n 
F 1 27  PHE 27  39  39  PHE PHE A . n 
F 1 28  TYR 28  40  40  TYR TYR A . n 
F 1 29  ILE 29  41  41  ILE ILE A . n 
F 1 30  GLN 30  42  42  GLN GLN A . n 
F 1 31  MET 31  43  43  MET MET A . n 
F 1 32  CYS 32  44  44  CYS CYS A . n 
F 1 33  THR 33  45  45  THR THR A . n 
F 1 34  GLU 34  46  46  GLU GLU A . n 
F 1 35  LEU 35  47  47  LEU LEU A . n 
F 1 36  LYS 36  48  48  LYS LYS A . n 
F 1 37  LEU 37  49  49  LEU LEU A . n 
F 1 38  SER 38  50  50  SER SER A . n 
F 1 39  ASP 39  51  51  ASP ASP A . n 
F 1 40  TYR 40  52  52  TYR TYR A . n 
F 1 41  GLU 41  53  53  GLU GLU A . n 
F 1 42  GLY 42  54  54  GLY GLY A . n 
F 1 43  ARG 43  55  55  ARG ARG A . n 
F 1 44  LEU 44  56  56  LEU LEU A . n 
F 1 45  ILE 45  57  57  ILE ILE A . n 
F 1 46  GLN 46  58  58  GLN GLN A . n 
F 1 47  ASN 47  59  59  ASN ASN A . n 
F 1 48  SER 48  60  60  SER SER A . n 
F 1 49  LEU 49  61  61  LEU LEU A . n 
F 1 50  THR 50  62  62  THR THR A . n 
F 1 51  ILE 51  63  63  ILE ILE A . n 
F 1 52  GLU 52  64  64  GLU GLU A . n 
F 1 53  ARG 53  65  65  ARG ARG A . n 
F 1 54  MET 54  66  66  MET MET A . n 
F 1 55  VAL 55  67  67  VAL VAL A . n 
F 1 56  LEU 56  68  68  LEU LEU A . n 
F 1 57  SER 57  69  69  SER SER A . n 
F 1 58  ALA 58  70  70  ALA ALA A . n 
F 1 59  PHE 59  71  71  PHE PHE A . n 
F 1 60  ASP 60  72  72  ASP ASP A . n 
F 1 61  GLU 61  73  73  GLU GLU A . n 
F 1 62  ARG 62  74  74  ARG ARG A . n 
F 1 63  ARG 63  75  75  ARG ARG A . n 
F 1 64  ASN 64  76  76  ASN ASN A . n 
F 1 65  LYS 65  77  77  LYS LYS A . n 
F 1 66  TYR 66  78  78  TYR TYR A . n 
F 1 67  LEU 67  79  79  LEU LEU A . n 
F 1 68  GLU 68  80  80  GLU GLU A . n 
F 1 69  GLU 69  81  81  GLU GLU A . n 
F 1 70  HIS 70  82  82  HIS HIS A . n 
F 1 71  PRO 71  83  83  PRO PRO A . n 
F 1 72  SER 72  84  84  SER SER A . n 
F 1 73  ALA 73  85  85  ALA ALA A . n 
F 1 74  GLY 74  86  86  GLY GLY A . n 
F 1 75  LYS 75  87  87  LYS LYS A . n 
F 1 76  ASP 76  88  88  ASP ASP A . n 
F 1 77  PRO 77  89  89  PRO PRO A . n 
F 1 78  LYS 78  90  90  LYS LYS A . n 
F 1 79  LYS 79  91  91  LYS LYS A . n 
F 1 80  THR 80  92  92  THR THR A . n 
F 1 81  GLY 81  93  93  GLY GLY A . n 
F 1 82  GLY 82  94  94  GLY GLY A . n 
F 1 83  PRO 83  95  95  PRO PRO A . n 
F 1 84  ILE 84  96  96  ILE ILE A . n 
F 1 85  TYR 85  97  97  TYR TYR A . n 
F 1 86  ARG 86  98  98  ARG ARG A . n 
F 1 87  ARG 87  99  99  ARG ARG A . n 
F 1 88  VAL 88  100 100 VAL VAL A . n 
F 1 89  ASP 89  101 101 ASP ASP A . n 
F 1 90  GLY 90  102 102 GLY GLY A . n 
F 1 91  LYS 91  103 103 LYS LYS A . n 
F 1 92  TRP 92  104 104 TRP TRP A . n 
F 1 93  ARG 93  105 105 ARG ARG A . n 
F 1 94  ARG 94  106 106 ARG ARG A . n 
F 1 95  GLU 95  107 107 GLU GLU A . n 
F 1 96  LEU 96  108 108 LEU LEU A . n 
F 1 97  ILE 97  109 109 ILE ILE A . n 
F 1 98  LEU 98  110 110 LEU LEU A . n 
F 1 99  TYR 99  111 111 TYR TYR A . n 
F 1 100 ASP 100 112 112 ASP ASP A . n 
F 1 101 LYS 101 113 113 LYS LYS A . n 
F 1 102 GLU 102 114 114 GLU GLU A . n 
F 1 103 GLU 103 115 115 GLU GLU A . n 
F 1 104 ILE 104 116 116 ILE ILE A . n 
F 1 105 ARG 105 117 117 ARG ARG A . n 
F 1 106 ARG 106 118 118 ARG ARG A . n 
F 1 107 ILE 107 119 119 ILE ILE A . n 
F 1 108 TRP 108 120 120 TRP TRP A . n 
F 1 109 ARG 109 121 121 ARG ARG A . n 
F 1 110 GLN 110 122 122 GLN GLN A . n 
F 1 111 ALA 111 123 123 ALA ALA A . n 
F 1 112 ASN 112 124 124 ASN ASN A . n 
F 1 113 ASN 113 125 125 ASN ASN A . n 
F 1 114 GLY 114 126 126 GLY GLY A . n 
F 1 115 ASP 115 127 127 ASP ASP A . n 
F 1 116 ASP 116 128 128 ASP ASP A . n 
F 1 117 ALA 117 129 129 ALA ALA A . n 
F 1 118 THR 118 130 130 THR THR A . n 
F 1 119 ALA 119 131 131 ALA ALA A . n 
F 1 120 GLY 120 132 132 GLY GLY A . n 
F 1 121 LEU 121 133 133 LEU LEU A . n 
F 1 122 THR 122 134 134 THR THR A . n 
F 1 123 HIS 123 135 135 HIS HIS A . n 
F 1 124 MET 124 136 136 MET MET A . n 
F 1 125 MET 125 137 137 MET MET A . n 
F 1 126 ILE 126 138 138 ILE ILE A . n 
F 1 127 TRP 127 139 139 TRP TRP A . n 
F 1 128 HIS 128 140 140 HIS HIS A . n 
F 1 129 SER 129 141 141 SER SER A . n 
F 1 130 ASN 130 142 142 ASN ASN A . n 
F 1 131 LEU 131 143 143 LEU LEU A . n 
F 1 132 ASN 132 144 144 ASN ASN A . n 
F 1 133 ASP 133 145 145 ASP ASP A . n 
F 1 134 ALA 134 146 146 ALA ALA A . n 
F 1 135 THR 135 147 147 THR THR A . n 
F 1 136 TYR 136 148 148 TYR TYR A . n 
F 1 137 GLN 137 149 149 GLN GLN A . n 
F 1 138 ARG 138 150 150 ARG ARG A . n 
F 1 139 THR 139 151 151 THR THR A . n 
F 1 140 ARG 140 152 152 ARG ARG A . n 
F 1 141 ALA 141 153 153 ALA ALA A . n 
F 1 142 LEU 142 154 154 LEU LEU A . n 
F 1 143 VAL 143 155 155 VAL VAL A . n 
F 1 144 ARG 144 156 156 ARG ARG A . n 
F 1 145 THR 145 157 157 THR THR A . n 
F 1 146 GLY 146 158 158 GLY GLY A . n 
F 1 147 MET 147 159 159 MET MET A . n 
F 1 148 ASP 148 160 160 ASP ASP A . n 
F 1 149 PRO 149 161 161 PRO PRO A . n 
F 1 150 ARG 150 162 162 ARG ARG A . n 
F 1 151 MET 151 163 163 MET MET A . n 
F 1 152 CYS 152 164 164 CYS CYS A . n 
F 1 153 SER 153 165 165 SER SER A . n 
F 1 154 LEU 154 166 166 LEU LEU A . n 
F 1 155 MET 155 167 167 MET MET A . n 
F 1 156 GLN 156 168 168 GLN GLN A . n 
F 1 157 GLY 157 169 169 GLY GLY A . n 
F 1 158 SER 158 170 170 SER SER A . n 
F 1 159 THR 159 171 171 THR THR A . n 
F 1 160 LEU 160 172 172 LEU LEU A . n 
F 1 161 PRO 161 173 173 PRO PRO A . n 
F 1 162 ARG 162 174 174 ARG ARG A . n 
F 1 163 ARG 163 175 175 ARG ARG A . n 
F 1 164 SER 164 176 176 SER SER A . n 
F 1 165 GLY 165 177 177 GLY GLY A . n 
F 1 166 ALA 166 178 178 ALA ALA A . n 
F 1 167 ALA 167 179 179 ALA ALA A . n 
F 1 168 GLY 168 180 180 GLY GLY A . n 
F 1 169 ALA 169 181 181 ALA ALA A . n 
F 1 170 ALA 170 182 182 ALA ALA A . n 
F 1 171 VAL 171 183 183 VAL VAL A . n 
F 1 172 LYS 172 184 184 LYS LYS A . n 
F 1 173 GLY 173 185 185 GLY GLY A . n 
F 1 174 VAL 174 186 186 VAL VAL A . n 
F 1 175 GLY 175 187 187 GLY GLY A . n 
F 1 176 THR 176 188 188 THR THR A . n 
F 1 177 MET 177 189 189 MET MET A . n 
F 1 178 VAL 178 190 190 VAL VAL A . n 
F 1 179 MET 179 191 191 MET MET A . n 
F 1 180 GLU 180 192 192 GLU GLU A . n 
F 1 181 LEU 181 193 193 LEU LEU A . n 
F 1 182 ILE 182 194 194 ILE ILE A . n 
F 1 183 ARG 183 195 195 ARG ARG A . n 
F 1 184 MET 184 196 196 MET MET A . n 
F 1 185 ILE 185 197 197 ILE ILE A . n 
F 1 186 LYS 186 198 198 LYS LYS A . n 
F 1 187 ARG 187 199 199 ARG ARG A . n 
F 1 188 GLY 188 200 200 GLY GLY A . n 
F 1 189 ILE 189 201 201 ILE ILE A . n 
F 1 190 ASN 190 202 202 ASN ASN A . n 
F 1 191 ASP 191 203 203 ASP ASP A . n 
F 1 192 ARG 192 204 204 ARG ARG A . n 
F 1 193 ASN 193 205 205 ASN ASN A . n 
F 1 194 PHE 194 206 206 PHE PHE A . n 
F 1 195 TRP 195 207 207 TRP TRP A . n 
F 1 196 ARG 196 208 208 ARG ARG A . n 
F 1 197 GLY 197 209 209 GLY GLY A . n 
F 1 198 GLU 198 210 210 GLU GLU A . n 
F 1 199 ASN 199 211 211 ASN ASN A . n 
F 1 200 GLY 200 212 212 GLY GLY A . n 
F 1 201 ARG 201 213 213 ARG ARG A . n 
F 1 202 ARG 202 214 214 ARG ARG A . n 
F 1 203 THR 203 215 215 THR THR A . n 
F 1 204 ARG 204 216 216 ARG ARG A . n 
F 1 205 ILE 205 217 217 ILE ILE A . n 
F 1 206 ALA 206 218 218 ALA ALA A . n 
F 1 207 TYR 207 219 219 TYR TYR A . n 
F 1 208 GLU 208 220 220 GLU GLU A . n 
F 1 209 ARG 209 221 221 ARG ARG A . n 
F 1 210 MET 210 222 222 MET MET A . n 
F 1 211 CYS 211 223 223 CYS CYS A . n 
F 1 212 ASN 212 224 224 ASN ASN A . n 
F 1 213 ILE 213 225 225 ILE ILE A . n 
F 1 214 LEU 214 226 226 LEU LEU A . n 
F 1 215 LYS 215 227 227 LYS LYS A . n 
F 1 216 GLY 216 228 228 GLY GLY A . n 
F 1 217 LYS 217 229 229 LYS LYS A . n 
F 1 218 PHE 218 230 230 PHE PHE A . n 
F 1 219 GLN 219 231 231 GLN GLN A . n 
F 1 220 THR 220 232 232 THR THR A . n 
F 1 221 ALA 221 233 233 ALA ALA A . n 
F 1 222 ALA 222 234 234 ALA ALA A . n 
F 1 223 GLN 223 235 235 GLN GLN A . n 
F 1 224 ARG 224 236 236 ARG ARG A . n 
F 1 225 THR 225 237 237 THR THR A . n 
F 1 226 MET 226 238 238 MET MET A . n 
F 1 227 VAL 227 239 239 VAL VAL A . n 
F 1 228 ASP 228 240 240 ASP ASP A . n 
F 1 229 GLN 229 241 241 GLN GLN A . n 
F 1 230 VAL 230 242 242 VAL VAL A . n 
F 1 231 ARG 231 243 243 ARG ARG A . n 
F 1 232 GLU 232 244 244 GLU GLU A . n 
F 1 233 SER 233 245 245 SER SER A . n 
F 1 234 ARG 234 246 246 ARG ARG A . n 
F 1 235 ASN 235 247 247 ASN ASN A . n 
F 1 236 PRO 236 248 248 PRO PRO A . n 
F 1 237 GLY 237 249 249 GLY GLY A . n 
F 1 238 ASN 238 250 250 ASN ASN A . n 
F 1 239 ALA 239 251 251 ALA ALA A . n 
F 1 240 GLU 240 252 252 GLU GLU A . n 
F 1 241 PHE 241 253 253 PHE PHE A . n 
F 1 242 GLU 242 254 254 GLU GLU A . n 
F 1 243 ASP 243 255 255 ASP ASP A . n 
F 1 244 LEU 244 256 256 LEU LEU A . n 
F 1 245 ILE 245 257 257 ILE ILE A . n 
F 1 246 PHE 246 258 258 PHE PHE A . n 
F 1 247 LEU 247 259 259 LEU LEU A . n 
F 1 248 ALA 248 260 260 ALA ALA A . n 
F 1 249 ARG 249 261 261 ARG ARG A . n 
F 1 250 SER 250 262 262 SER SER A . n 
F 1 251 ALA 251 263 263 ALA ALA A . n 
F 1 252 LEU 252 264 264 LEU LEU A . n 
F 1 253 ILE 253 265 265 ILE ILE A . n 
F 1 254 LEU 254 266 266 LEU LEU A . n 
F 1 255 ARG 255 267 267 ARG ARG A . n 
F 1 256 GLY 256 268 268 GLY GLY A . n 
F 1 257 SER 257 269 269 SER SER A . n 
F 1 258 VAL 258 270 270 VAL VAL A . n 
F 1 259 ALA 259 271 271 ALA ALA A . n 
F 1 260 HIS 260 272 272 HIS HIS A . n 
F 1 261 LYS 261 273 273 LYS LYS A . n 
F 1 262 SER 262 274 274 SER SER A . n 
F 1 263 CYS 263 275 275 CYS CYS A . n 
F 1 264 LEU 264 276 276 LEU LEU A . n 
F 1 265 PRO 265 277 277 PRO PRO A . n 
F 1 266 ALA 266 278 278 ALA ALA A . n 
F 1 267 CYS 267 279 279 CYS CYS A . n 
F 1 268 VAL 268 280 280 VAL VAL A . n 
F 1 269 TYR 269 281 281 TYR TYR A . n 
F 1 270 GLY 270 282 282 GLY GLY A . n 
F 1 271 SER 271 283 283 SER SER A . n 
F 1 272 ALA 272 284 284 ALA ALA A . n 
F 1 273 VAL 273 285 285 VAL VAL A . n 
F 1 274 ALA 274 286 286 ALA ALA A . n 
F 1 275 SER 275 287 287 SER SER A . n 
F 1 276 GLY 276 288 288 GLY GLY A . n 
F 1 277 TYR 277 289 289 TYR TYR A . n 
F 1 278 ASP 278 290 290 ASP ASP A . n 
F 1 279 PHE 279 291 291 PHE PHE A . n 
F 1 280 GLU 280 292 292 GLU GLU A . n 
F 1 281 ARG 281 293 293 ARG ARG A . n 
F 1 282 GLU 282 294 294 GLU GLU A . n 
F 1 283 GLY 283 295 295 GLY GLY A . n 
F 1 284 TYR 284 296 296 TYR TYR A . n 
F 1 285 SER 285 297 297 SER SER A . n 
F 1 286 LEU 286 298 298 LEU LEU A . n 
F 1 287 VAL 287 299 299 VAL VAL A . n 
F 1 288 GLY 288 300 300 GLY GLY A . n 
F 1 289 ILE 289 301 301 ILE ILE A . n 
F 1 290 ASP 290 302 302 ASP ASP A . n 
F 1 291 PRO 291 303 303 PRO PRO A . n 
F 1 292 PHE 292 304 304 PHE PHE A . n 
F 1 293 ARG 293 305 305 ARG ARG A . n 
F 1 294 LEU 294 306 306 LEU LEU A . n 
F 1 295 LEU 295 307 307 LEU LEU A . n 
F 1 296 GLN 296 308 308 GLN GLN A . n 
F 1 297 ASN 297 309 309 ASN ASN A . n 
F 1 298 SER 298 310 310 SER SER A . n 
F 1 299 GLN 299 311 311 GLN GLN A . n 
F 1 300 VAL 300 312 312 VAL VAL A . n 
F 1 301 TYR 301 313 313 TYR TYR A . n 
F 1 302 SER 302 314 314 SER SER A . n 
F 1 303 LEU 303 315 315 LEU LEU A . n 
F 1 304 ILE 304 316 316 ILE ILE A . n 
F 1 305 ARG 305 317 317 ARG ARG A . n 
F 1 306 PRO 306 318 318 PRO PRO A . n 
F 1 307 ASN 307 319 319 ASN ASN A . n 
F 1 308 GLU 308 320 320 GLU GLU A . n 
F 1 309 ASN 309 321 321 ASN ASN A . n 
F 1 310 PRO 310 322 322 PRO PRO A . n 
F 1 311 ALA 311 323 323 ALA ALA A . n 
F 1 312 HIS 312 324 324 HIS HIS A . n 
F 1 313 LYS 313 325 325 LYS LYS A . n 
F 1 314 SER 314 326 326 SER SER A . n 
F 1 315 GLN 315 327 327 GLN GLN A . n 
F 1 316 LEU 316 328 328 LEU LEU A . n 
F 1 317 VAL 317 329 329 VAL VAL A . n 
F 1 318 TRP 318 330 330 TRP TRP A . n 
F 1 319 MET 319 331 331 MET MET A . n 
F 1 320 ALA 320 332 332 ALA ALA A . n 
F 1 321 CYS 321 333 333 CYS CYS A . n 
F 1 322 HIS 322 334 334 HIS HIS A . n 
F 1 323 SER 323 335 335 SER SER A . n 
F 1 324 ALA 324 336 336 ALA ALA A . n 
F 1 325 ALA 325 337 337 ALA ALA A . n 
F 1 326 PHE 326 338 338 PHE PHE A . n 
F 1 327 GLU 327 339 339 GLU GLU A . n 
F 1 328 ASP 328 340 340 ASP ASP A . n 
F 1 329 LEU 329 341 341 LEU LEU A . n 
F 1 330 ARG 330 342 342 ARG ARG A . n 
F 1 331 VAL 331 343 343 VAL VAL A . n 
F 1 332 SER 332 344 344 SER SER A . n 
F 1 333 SER 333 345 345 SER SER A . n 
F 1 334 PHE 334 346 346 PHE PHE A . n 
F 1 335 ILE 335 347 347 ILE ILE A . n 
F 1 336 ARG 336 348 348 ARG ARG A . n 
F 1 337 GLY 337 349 349 GLY GLY A . n 
F 1 338 THR 338 350 350 THR THR A . n 
F 1 339 LYS 339 351 351 LYS LYS A . n 
F 1 340 VAL 340 352 352 VAL VAL A . n 
F 1 341 VAL 341 353 353 VAL VAL A . n 
F 1 342 PRO 342 354 354 PRO PRO A . n 
F 1 343 ARG 343 355 355 ARG ARG A . n 
F 1 344 GLY 344 356 356 GLY GLY A . n 
F 1 345 LYS 345 357 357 LYS LYS A . n 
F 1 346 LEU 346 358 358 LEU LEU A . n 
F 1 347 SER 347 359 359 SER SER A . n 
F 1 348 THR 348 360 360 THR THR A . n 
F 1 349 ARG 349 361 361 ARG ARG A . n 
F 1 350 GLY 350 362 362 GLY GLY A . n 
F 1 351 VAL 351 363 363 VAL VAL A . n 
F 1 352 GLN 352 364 364 GLN GLN A . n 
F 1 353 ILE 353 365 365 ILE ILE A . n 
F 1 354 ALA 354 366 366 ALA ALA A . n 
F 1 355 SER 355 367 367 SER SER A . n 
F 1 356 ASN 356 368 368 ASN ASN A . n 
F 1 357 GLU 357 369 369 GLU GLU A . n 
F 1 358 ASN 358 370 370 ASN ASN A . n 
F 1 359 MET 359 371 371 MET MET A . n 
F 1 360 GLU 360 372 372 GLU GLU A . n 
F 1 361 THR 361 373 373 THR THR A . n 
F 1 362 MET 362 374 374 MET MET A . n 
F 1 363 GLU 363 375 375 GLU GLU A . n 
F 1 364 SER 364 376 376 SER SER A . n 
F 1 365 SER 365 377 377 SER SER A . n 
F 1 366 THR 366 378 378 THR THR A . n 
F 1 367 LEU 367 379 379 LEU LEU A . n 
F 1 368 GLU 368 380 380 GLU GLU A . n 
F 1 369 LEU 369 381 381 LEU LEU A . n 
F 1 370 ARG 370 382 382 ARG ARG A . n 
F 1 371 SER 371 383 383 SER SER A . n 
F 1 372 ARG 372 384 384 ARG ARG A . n 
F 1 373 TYR 373 385 385 TYR TYR A . n 
F 1 374 TRP 374 386 386 TRP TRP A . n 
F 1 375 ALA 375 387 387 ALA ALA A . n 
F 1 376 ILE 376 388 388 ILE ILE A . n 
F 1 377 ARG 377 389 389 ARG ARG A . n 
F 1 378 THR 378 390 390 THR THR A . n 
F 1 379 ARG 379 391 391 ARG ARG A . n 
F 1 380 SER 380 392 392 SER SER A . n 
F 1 381 GLY 381 393 393 GLY GLY A . n 
F 1 382 GLY 382 394 394 GLY GLY A . n 
F 1 383 ASN 383 395 395 ASN ASN A . n 
F 1 384 THR 384 396 ?   ?   ?   A . n 
F 1 385 ASN 385 397 ?   ?   ?   A . n 
F 1 386 GLN 386 398 ?   ?   ?   A . n 
F 1 387 GLN 387 399 ?   ?   ?   A . n 
F 1 388 ARG 388 400 ?   ?   ?   A . n 
F 1 389 ALA 389 401 ?   ?   ?   A . n 
F 1 390 SER 390 402 ?   ?   ?   A . n 
F 1 391 SER 391 403 ?   ?   ?   A . n 
F 1 392 GLY 392 404 ?   ?   ?   A . n 
F 1 393 GLN 393 405 ?   ?   ?   A . n 
F 1 394 ILE 394 406 ?   ?   ?   A . n 
F 1 395 SER 395 407 ?   ?   ?   A . n 
F 1 396 ILE 396 408 ?   ?   ?   A . n 
F 1 397 GLN 397 409 ?   ?   ?   A . n 
F 1 398 PRO 398 410 ?   ?   ?   A . n 
F 1 399 THR 399 411 ?   ?   ?   A . n 
F 1 400 PHE 400 412 ?   ?   ?   A . n 
F 1 401 SER 401 413 ?   ?   ?   A . n 
F 1 402 VAL 402 414 ?   ?   ?   A . n 
F 1 403 GLN 403 415 ?   ?   ?   A . n 
F 1 404 ARG 404 416 ?   ?   ?   A . n 
F 1 405 ASN 405 417 ?   ?   ?   A . n 
F 1 406 LEU 406 418 ?   ?   ?   A . n 
F 1 407 PRO 407 419 ?   ?   ?   A . n 
F 1 408 PHE 408 420 ?   ?   ?   A . n 
F 1 409 ASP 409 421 ?   ?   ?   A . n 
F 1 410 ARG 410 422 ?   ?   ?   A . n 
F 1 411 PRO 411 423 ?   ?   ?   A . n 
F 1 412 THR 412 424 ?   ?   ?   A . n 
F 1 413 ILE 413 425 ?   ?   ?   A . n 
F 1 414 MET 414 426 ?   ?   ?   A . n 
F 1 415 ALA 415 427 ?   ?   ?   A . n 
F 1 416 ALA 416 428 ?   ?   ?   A . n 
F 1 417 PHE 417 429 ?   ?   ?   A . n 
F 1 418 THR 418 430 ?   ?   ?   A . n 
F 1 419 GLY 419 431 ?   ?   ?   A . n 
F 1 420 ASN 420 432 ?   ?   ?   A . n 
F 1 421 THR 421 433 ?   ?   ?   A . n 
F 1 422 GLU 422 434 ?   ?   ?   A . n 
F 1 423 GLY 423 435 ?   ?   ?   A . n 
F 1 424 ARG 424 436 ?   ?   ?   A . n 
F 1 425 THR 425 437 ?   ?   ?   A . n 
F 1 426 SER 426 438 ?   ?   ?   A . n 
F 1 427 ASP 427 439 ?   ?   ?   A . n 
F 1 428 MET 428 440 440 MET MET A . n 
F 1 429 ARG 429 441 441 ARG ARG A . n 
F 1 430 THR 430 442 442 THR THR A . n 
F 1 431 GLU 431 443 443 GLU GLU A . n 
F 1 432 ILE 432 444 444 ILE ILE A . n 
F 1 433 ILE 433 445 445 ILE ILE A . n 
F 1 434 ARG 434 446 446 ARG ARG A . n 
F 1 435 LEU 435 447 447 LEU LEU A . n 
F 1 436 MET 436 448 448 MET MET A . n 
F 1 437 GLU 437 449 449 GLU GLU A . n 
F 1 438 SER 438 450 450 SER SER A . n 
F 1 439 ALA 439 451 451 ALA ALA A . n 
F 1 440 ARG 440 452 452 ARG ARG A . n 
F 1 441 PRO 441 453 453 PRO PRO A . n 
F 1 442 GLU 442 454 454 GLU GLU A . n 
F 1 443 ASP 443 455 455 ASP ASP A . n 
F 1 444 VAL 444 456 456 VAL VAL A . n 
F 1 445 SER 445 457 457 SER SER A . n 
F 1 446 PHE 446 458 458 PHE PHE A . n 
F 1 447 GLN 447 459 459 GLN GLN A . n 
F 1 448 GLY 448 460 460 GLY GLY A . n 
F 1 449 ARG 449 461 461 ARG ARG A . n 
F 1 450 GLY 450 462 462 GLY GLY A . n 
F 1 451 VAL 451 463 463 VAL VAL A . n 
F 1 452 PHE 452 464 464 PHE PHE A . n 
F 1 453 GLU 453 465 465 GLU GLU A . n 
F 1 454 LEU 454 466 466 LEU LEU A . n 
F 1 455 SER 455 467 467 SER SER A . n 
F 1 456 ASP 456 468 468 ASP ASP A . n 
F 1 457 GLU 457 469 469 GLU GLU A . n 
F 1 458 LYS 458 470 470 LYS LYS A . n 
F 1 459 ALA 459 471 471 ALA ALA A . n 
F 1 460 THR 460 472 472 THR THR A . n 
F 1 461 SER 461 473 473 SER SER A . n 
F 1 462 PRO 462 474 474 PRO PRO A . n 
F 1 463 ILE 463 475 475 ILE ILE A . n 
F 1 464 VAL 464 476 476 VAL VAL A . n 
F 1 465 PRO 465 477 477 PRO PRO A . n 
F 1 466 SER 466 478 478 SER SER A . n 
F 1 467 PHE 467 479 479 PHE PHE A . n 
F 1 468 ASP 468 480 ?   ?   ?   A . n 
F 1 469 MET 469 481 ?   ?   ?   A . n 
F 1 470 SER 470 482 ?   ?   ?   A . n 
F 1 471 ASN 471 483 ?   ?   ?   A . n 
F 1 472 GLU 472 484 484 GLU GLU A . n 
F 1 473 GLY 473 485 485 GLY GLY A . n 
F 1 474 SER 474 486 486 SER SER A . n 
F 1 475 TYR 475 487 487 TYR TYR A . n 
F 1 476 PHE 476 488 488 PHE PHE A . n 
F 1 477 PHE 477 489 489 PHE PHE A . n 
F 1 478 GLY 478 490 490 GLY GLY A . n 
F 1 479 ASP 479 491 ?   ?   ?   A . n 
F 1 480 ASN 480 492 ?   ?   ?   A . n 
F 1 481 ALA 481 493 ?   ?   ?   A . n 
F 1 482 GLU 482 494 ?   ?   ?   A . n 
F 1 483 GLU 483 495 ?   ?   ?   A . n 
F 1 484 TYR 484 496 ?   ?   ?   A . n 
F 1 485 ASP 485 497 ?   ?   ?   A . n 
F 1 486 ASN 486 498 ?   ?   ?   A . n 
F 1 487 LEU 487 499 ?   ?   ?   A . n 
F 1 488 GLU 488 500 ?   ?   ?   A . n 
F 1 489 HIS 489 501 ?   ?   ?   A . n 
F 1 490 HIS 490 502 ?   ?   ?   A . n 
F 1 491 HIS 491 503 ?   ?   ?   A . n 
F 1 492 HIS 492 504 ?   ?   ?   A . n 
F 1 493 HIS 493 505 ?   ?   ?   A . n 
F 1 494 HIS 494 506 ?   ?   ?   A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 3 A1IJK 1 101 18 A1IJK 6FM D . 
H 3 A1IJK 1 101 18 A1IJK 6FM E . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 D C 18 ? OP2 ? B C 12 OP2 
2 1 Y 1 E C 18 ? OP1 ? C C 18 OP1 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GAV 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GAV 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GAV 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9GAV 
_struct.title                        
'Focused reconstruction on strand 1 of the influenza A RNP-like particle double-stranded assembled with a 18-mer RNA.' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GAV 
_struct_keywords.text            'Nucleoprotein, RNA, complex, RNP-like, influenza virus, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 2 ? 
E N N 1 ? 
F N N 1 ? 
G N N 3 ? 
H N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP Q1K9H2_I33A0 Q1K9H2 ? 1 
;TDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGG
PIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPR
RSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAEFE
DLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMACH
SAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTFSV
QRNLPFDRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDNAE
EYDN
;
15 
2 PDB 9GAV         9GAV   ? 2 ? 1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9GAV G 3 ? 486 ? Q1K9H2 15 ? 498 ? 15 498 
2 2 9GAV D 1 ? 18  ? 9GAV   7  ? 24  ? 7  24  
3 2 9GAV E 1 ? 18  ? 9GAV   1  ? 18  ? 1  18  
4 2 9GAV F 1 ? 18  ? 9GAV   1  ? 18  ? 1  18  
5 1 9GAV B 3 ? 486 ? Q1K9H2 15 ? 498 ? 15 498 
6 1 9GAV A 3 ? 486 ? Q1K9H2 15 ? 498 ? 15 498 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9GAV HIS G 1   ? UNP Q1K9H2 ? ? 'expression tag' 13  1  
1 9GAV MET G 2   ? UNP Q1K9H2 ? ? 'expression tag' 14  2  
1 9GAV LEU G 487 ? UNP Q1K9H2 ? ? 'expression tag' 499 3  
1 9GAV GLU G 488 ? UNP Q1K9H2 ? ? 'expression tag' 500 4  
1 9GAV HIS G 489 ? UNP Q1K9H2 ? ? 'expression tag' 501 5  
1 9GAV HIS G 490 ? UNP Q1K9H2 ? ? 'expression tag' 502 6  
1 9GAV HIS G 491 ? UNP Q1K9H2 ? ? 'expression tag' 503 7  
1 9GAV HIS G 492 ? UNP Q1K9H2 ? ? 'expression tag' 504 8  
1 9GAV HIS G 493 ? UNP Q1K9H2 ? ? 'expression tag' 505 9  
1 9GAV HIS G 494 ? UNP Q1K9H2 ? ? 'expression tag' 506 10 
5 9GAV HIS B 1   ? UNP Q1K9H2 ? ? 'expression tag' 13  11 
5 9GAV MET B 2   ? UNP Q1K9H2 ? ? 'expression tag' 14  12 
5 9GAV LEU B 487 ? UNP Q1K9H2 ? ? 'expression tag' 499 13 
5 9GAV GLU B 488 ? UNP Q1K9H2 ? ? 'expression tag' 500 14 
5 9GAV HIS B 489 ? UNP Q1K9H2 ? ? 'expression tag' 501 15 
5 9GAV HIS B 490 ? UNP Q1K9H2 ? ? 'expression tag' 502 16 
5 9GAV HIS B 491 ? UNP Q1K9H2 ? ? 'expression tag' 503 17 
5 9GAV HIS B 492 ? UNP Q1K9H2 ? ? 'expression tag' 504 18 
5 9GAV HIS B 493 ? UNP Q1K9H2 ? ? 'expression tag' 505 19 
5 9GAV HIS B 494 ? UNP Q1K9H2 ? ? 'expression tag' 506 20 
6 9GAV HIS A 1   ? UNP Q1K9H2 ? ? 'expression tag' 13  21 
6 9GAV MET A 2   ? UNP Q1K9H2 ? ? 'expression tag' 14  22 
6 9GAV LEU A 487 ? UNP Q1K9H2 ? ? 'expression tag' 499 23 
6 9GAV GLU A 488 ? UNP Q1K9H2 ? ? 'expression tag' 500 24 
6 9GAV HIS A 489 ? UNP Q1K9H2 ? ? 'expression tag' 501 25 
6 9GAV HIS A 490 ? UNP Q1K9H2 ? ? 'expression tag' 502 26 
6 9GAV HIS A 491 ? UNP Q1K9H2 ? ? 'expression tag' 503 27 
6 9GAV HIS A 492 ? UNP Q1K9H2 ? ? 'expression tag' 504 28 
6 9GAV HIS A 493 ? UNP Q1K9H2 ? ? 'expression tag' 505 29 
6 9GAV HIS A 494 ? UNP Q1K9H2 ? ? 'expression tag' 506 30 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 409 ? ALA A 416 ? ASP G 421 ALA G 428 1 ? 8  
HELX_P HELX_P2  AA2 GLY E 5   ? LYS E 36  ? GLY B 17  LYS B 48  1 ? 32 
HELX_P HELX_P3  AA3 SER E 38  ? ARG E 43  ? SER B 50  ARG B 55  1 ? 6  
HELX_P HELX_P4  AA4 LEU E 44  ? PHE E 59  ? LEU B 56  PHE B 71  1 ? 16 
HELX_P HELX_P5  AA5 ASP E 60  ? HIS E 70  ? ASP B 72  HIS B 82  1 ? 11 
HELX_P HELX_P6  AA6 LYS E 101 ? ASN E 112 ? LYS B 113 ASN B 124 1 ? 12 
HELX_P HELX_P7  AA7 ALA E 117 ? TYR E 136 ? ALA B 129 TYR B 148 1 ? 20 
HELX_P HELX_P8  AA8 ARG E 138 ? THR E 145 ? ARG B 150 THR B 157 1 ? 8  
HELX_P HELX_P9  AA9 MET E 151 ? MET E 155 ? MET B 163 MET B 167 5 ? 5  
HELX_P HELX_P10 AB1 ALA E 166 ? LYS E 172 ? ALA B 178 LYS B 184 1 ? 7  
HELX_P HELX_P11 AB2 GLY E 173 ? ASP E 191 ? GLY B 185 ASP B 203 1 ? 19 
HELX_P HELX_P12 AB3 ARG E 196 ? PHE E 218 ? ARG B 208 PHE B 230 1 ? 23 
HELX_P HELX_P13 AB4 THR E 220 ? SER E 233 ? THR B 232 SER B 245 1 ? 14 
HELX_P HELX_P14 AB5 GLY E 237 ? LEU E 252 ? GLY B 249 LEU B 264 1 ? 16 
HELX_P HELX_P15 AB6 PRO E 265 ? SER E 275 ? PRO B 277 SER B 287 1 ? 11 
HELX_P HELX_P16 AB7 ASP E 278 ? GLY E 283 ? ASP B 290 GLY B 295 1 ? 6  
HELX_P HELX_P17 AB8 ILE E 289 ? SER E 298 ? ILE B 301 SER B 310 1 ? 10 
HELX_P HELX_P18 AB9 ASN E 309 ? HIS E 322 ? ASN B 321 HIS B 334 1 ? 14 
HELX_P HELX_P19 AC1 ASP E 328 ? GLY E 337 ? ASP B 340 GLY B 349 1 ? 10 
HELX_P HELX_P20 AC2 PRO E 342 ? LEU E 346 ? PRO B 354 LEU B 358 5 ? 5  
HELX_P HELX_P21 AC3 ASP E 409 ? ALA E 416 ? ASP B 421 ALA B 428 1 ? 8  
HELX_P HELX_P22 AC4 ARG E 429 ? ALA E 439 ? ARG B 441 ALA B 451 1 ? 11 
HELX_P HELX_P23 AC5 GLY F 5   ? LYS F 36  ? GLY A 17  LYS A 48  1 ? 32 
HELX_P HELX_P24 AC6 SER F 38  ? ARG F 43  ? SER A 50  ARG A 55  1 ? 6  
HELX_P HELX_P25 AC7 LEU F 44  ? PHE F 59  ? LEU A 56  PHE A 71  1 ? 16 
HELX_P HELX_P26 AC8 ASP F 60  ? HIS F 70  ? ASP A 72  HIS A 82  1 ? 11 
HELX_P HELX_P27 AC9 LYS F 101 ? ASN F 112 ? LYS A 113 ASN A 124 1 ? 12 
HELX_P HELX_P28 AD1 ALA F 117 ? TYR F 136 ? ALA A 129 TYR A 148 1 ? 20 
HELX_P HELX_P29 AD2 ARG F 138 ? THR F 145 ? ARG A 150 THR A 157 1 ? 8  
HELX_P HELX_P30 AD3 ALA F 166 ? LYS F 172 ? ALA A 178 LYS A 184 1 ? 7  
HELX_P HELX_P31 AD4 GLY F 173 ? ASP F 191 ? GLY A 185 ASP A 203 1 ? 19 
HELX_P HELX_P32 AD5 ARG F 196 ? PHE F 218 ? ARG A 208 PHE A 230 1 ? 23 
HELX_P HELX_P33 AD6 THR F 220 ? SER F 233 ? THR A 232 SER A 245 1 ? 14 
HELX_P HELX_P34 AD7 GLY F 237 ? LEU F 252 ? GLY A 249 LEU A 264 1 ? 16 
HELX_P HELX_P35 AD8 PRO F 265 ? SER F 275 ? PRO A 277 SER A 287 1 ? 11 
HELX_P HELX_P36 AD9 ASP F 278 ? GLY F 283 ? ASP A 290 GLY A 295 1 ? 6  
HELX_P HELX_P37 AE1 ILE F 289 ? ASN F 297 ? ILE A 301 ASN A 309 1 ? 9  
HELX_P HELX_P38 AE2 ASN F 309 ? SER F 323 ? ASN A 321 SER A 335 1 ? 15 
HELX_P HELX_P39 AE3 ASP F 328 ? GLY F 337 ? ASP A 340 GLY A 349 1 ? 10 
HELX_P HELX_P40 AE4 PRO F 342 ? LEU F 346 ? PRO A 354 LEU A 358 5 ? 5  
HELX_P HELX_P41 AE5 ARG F 429 ? ALA F 439 ? ARG A 441 ALA A 451 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale one ? B C 12 "O3'" ? ? ? 1_555 G A1IJK . C1 ? ? D C 18 D A1IJK 101 1_555 ? ? ? ? ? ? ? 1.430 ? ? 
covale2 covale one ? C C 18 "O3'" ? ? ? 1_555 H A1IJK . C1 ? ? E C 18 E A1IJK 101 1_555 ? ? ? ? ? ? ? 1.433 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS E 79  ? VAL E 88  ? LYS B 91  VAL B 100 
AA1 2 LYS E 91  ? ASP E 100 ? LYS B 103 ASP B 112 
AA2 1 VAL E 300 ? ILE E 304 ? VAL B 312 ILE B 316 
AA2 2 GLU E 363 ? LEU E 367 ? GLU B 375 LEU B 379 
AA3 1 TYR E 373 ? TRP E 374 ? TYR B 385 TRP B 386 
AA3 2 PHE E 452 ? GLU E 453 ? PHE B 464 GLU B 465 
AA4 1 LYS F 79  ? VAL F 88  ? LYS A 91  VAL A 100 
AA4 2 LYS F 91  ? ASP F 100 ? LYS A 103 ASP A 112 
AA5 1 TYR F 301 ? ILE F 304 ? TYR A 313 ILE A 316 
AA5 2 GLU F 363 ? THR F 366 ? GLU A 375 THR A 378 
AA6 1 TYR F 373 ? TRP F 374 ? TYR A 385 TRP A 386 
AA6 2 PHE F 452 ? GLU F 453 ? PHE A 464 GLU A 465 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR E 80  ? N THR B 92  O TYR E 99  ? O TYR B 111 
AA2 1 2 N ILE E 304 ? N ILE B 316 O GLU E 363 ? O GLU B 375 
AA3 1 2 N TRP E 374 ? N TRP B 386 O PHE E 452 ? O PHE B 464 
AA4 1 2 N THR F 80  ? N THR A 92  O TYR F 99  ? O TYR A 111 
AA5 1 2 N ILE F 304 ? N ILE A 316 O GLU F 363 ? O GLU A 375 
AA6 1 2 N TRP F 374 ? N TRP A 386 O PHE F 452 ? O PHE A 464 
# 
_pdbx_entry_details.entry_id                   9GAV 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 P E U 1 ? ? OP3 E U 1 ? ? 1.479 1.607 -0.128 0.012 N 
2 1 P F U 1 ? ? OP3 F U 1 ? ? 1.477 1.607 -0.130 0.012 N 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             "C3'" 
_pdbx_validate_rmsd_angle.auth_asym_id_1             E 
_pdbx_validate_rmsd_angle.auth_comp_id_1             U 
_pdbx_validate_rmsd_angle.auth_seq_id_1              17 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             "O3'" 
_pdbx_validate_rmsd_angle.auth_asym_id_2             E 
_pdbx_validate_rmsd_angle.auth_comp_id_2             U 
_pdbx_validate_rmsd_angle.auth_seq_id_2              17 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             P 
_pdbx_validate_rmsd_angle.auth_asym_id_3             E 
_pdbx_validate_rmsd_angle.auth_comp_id_3             C 
_pdbx_validate_rmsd_angle.auth_seq_id_3              18 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                107.17 
_pdbx_validate_rmsd_angle.angle_target_value         119.70 
_pdbx_validate_rmsd_angle.angle_deviation            -12.53 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.20 
_pdbx_validate_rmsd_angle.linker_flag                Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP B 16  ? ? 74.89   -7.61  
2  1 LYS B 48  ? ? 60.08   63.16  
3  1 ARG B 150 ? ? -100.61 75.32  
4  1 ALA B 178 ? ? 60.52   -79.14 
5  1 SER B 359 ? ? -92.78  59.11  
6  1 MET B 371 ? ? -84.19  49.93  
7  1 LEU B 381 ? ? -92.53  51.93  
8  1 PRO B 453 ? ? -78.08  44.80  
9  1 PHE B 489 ? ? -95.60  58.26  
10 1 ASP A 16  ? ? 74.73   -7.13  
11 1 ARG A 150 ? ? -101.22 75.79  
12 1 ALA A 178 ? ? 60.30   -80.25 
13 1 PRO A 453 ? ? -79.78  44.18  
14 1 GLU A 454 ? ? -141.16 -9.13  
15 1 PHE A 489 ? ? -95.94  58.42  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9GAV 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9GAV 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.04 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               276761 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               HELICAL 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       
;20 mM HEPES
150 mM NaCl
5 mM beta-mercaptoethanol
2 mM methyl-PEG8-NHS
;
_em_buffer.pH            7.5 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 'MULTIPLE SOURCES' COMPLEX 'complex NP-RNA' ? ? ? '1, 2' 
2 1 RECOMBINANT        COMPLEX Nucleoprotein    ? ? ? 1      
3 1 RECOMBINANT        COMPLEX RNA              ? ? ? 2      
# 
_em_imaging.entry_id                        9GAV 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS GLACIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           36000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_vitrification.entry_id              9GAV 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              98 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   298 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               '5 seconds blot at force 0' 
# 
_em_experiment.entry_id                9GAV 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   HELICAL 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 G HIS 13  ? A HIS 1   
2   1 Y 1 G MET 14  ? A MET 2   
3   1 Y 1 G THR 15  ? A THR 3   
4   1 Y 1 G ASP 16  ? A ASP 4   
5   1 Y 1 G GLY 17  ? A GLY 5   
6   1 Y 1 G GLU 18  ? A GLU 6   
7   1 Y 1 G ARG 19  ? A ARG 7   
8   1 Y 1 G GLN 20  ? A GLN 8   
9   1 Y 1 G ASN 21  ? A ASN 9   
10  1 Y 1 G ALA 22  ? A ALA 10  
11  1 Y 1 G THR 23  ? A THR 11  
12  1 Y 1 G GLU 24  ? A GLU 12  
13  1 Y 1 G ILE 25  ? A ILE 13  
14  1 Y 1 G ARG 26  ? A ARG 14  
15  1 Y 1 G ALA 27  ? A ALA 15  
16  1 Y 1 G SER 28  ? A SER 16  
17  1 Y 1 G VAL 29  ? A VAL 17  
18  1 Y 1 G GLY 30  ? A GLY 18  
19  1 Y 1 G LYS 31  ? A LYS 19  
20  1 Y 1 G MET 32  ? A MET 20  
21  1 Y 1 G ILE 33  ? A ILE 21  
22  1 Y 1 G ASP 34  ? A ASP 22  
23  1 Y 1 G GLY 35  ? A GLY 23  
24  1 Y 1 G ILE 36  ? A ILE 24  
25  1 Y 1 G GLY 37  ? A GLY 25  
26  1 Y 1 G ARG 38  ? A ARG 26  
27  1 Y 1 G PHE 39  ? A PHE 27  
28  1 Y 1 G TYR 40  ? A TYR 28  
29  1 Y 1 G ILE 41  ? A ILE 29  
30  1 Y 1 G GLN 42  ? A GLN 30  
31  1 Y 1 G MET 43  ? A MET 31  
32  1 Y 1 G CYS 44  ? A CYS 32  
33  1 Y 1 G THR 45  ? A THR 33  
34  1 Y 1 G GLU 46  ? A GLU 34  
35  1 Y 1 G LEU 47  ? A LEU 35  
36  1 Y 1 G LYS 48  ? A LYS 36  
37  1 Y 1 G LEU 49  ? A LEU 37  
38  1 Y 1 G SER 50  ? A SER 38  
39  1 Y 1 G ASP 51  ? A ASP 39  
40  1 Y 1 G TYR 52  ? A TYR 40  
41  1 Y 1 G GLU 53  ? A GLU 41  
42  1 Y 1 G GLY 54  ? A GLY 42  
43  1 Y 1 G ARG 55  ? A ARG 43  
44  1 Y 1 G LEU 56  ? A LEU 44  
45  1 Y 1 G ILE 57  ? A ILE 45  
46  1 Y 1 G GLN 58  ? A GLN 46  
47  1 Y 1 G ASN 59  ? A ASN 47  
48  1 Y 1 G SER 60  ? A SER 48  
49  1 Y 1 G LEU 61  ? A LEU 49  
50  1 Y 1 G THR 62  ? A THR 50  
51  1 Y 1 G ILE 63  ? A ILE 51  
52  1 Y 1 G GLU 64  ? A GLU 52  
53  1 Y 1 G ARG 65  ? A ARG 53  
54  1 Y 1 G MET 66  ? A MET 54  
55  1 Y 1 G VAL 67  ? A VAL 55  
56  1 Y 1 G LEU 68  ? A LEU 56  
57  1 Y 1 G SER 69  ? A SER 57  
58  1 Y 1 G ALA 70  ? A ALA 58  
59  1 Y 1 G PHE 71  ? A PHE 59  
60  1 Y 1 G ASP 72  ? A ASP 60  
61  1 Y 1 G GLU 73  ? A GLU 61  
62  1 Y 1 G ARG 74  ? A ARG 62  
63  1 Y 1 G ARG 75  ? A ARG 63  
64  1 Y 1 G ASN 76  ? A ASN 64  
65  1 Y 1 G LYS 77  ? A LYS 65  
66  1 Y 1 G TYR 78  ? A TYR 66  
67  1 Y 1 G LEU 79  ? A LEU 67  
68  1 Y 1 G GLU 80  ? A GLU 68  
69  1 Y 1 G GLU 81  ? A GLU 69  
70  1 Y 1 G HIS 82  ? A HIS 70  
71  1 Y 1 G PRO 83  ? A PRO 71  
72  1 Y 1 G SER 84  ? A SER 72  
73  1 Y 1 G ALA 85  ? A ALA 73  
74  1 Y 1 G GLY 86  ? A GLY 74  
75  1 Y 1 G LYS 87  ? A LYS 75  
76  1 Y 1 G ASP 88  ? A ASP 76  
77  1 Y 1 G PRO 89  ? A PRO 77  
78  1 Y 1 G LYS 90  ? A LYS 78  
79  1 Y 1 G LYS 91  ? A LYS 79  
80  1 Y 1 G THR 92  ? A THR 80  
81  1 Y 1 G GLY 93  ? A GLY 81  
82  1 Y 1 G GLY 94  ? A GLY 82  
83  1 Y 1 G PRO 95  ? A PRO 83  
84  1 Y 1 G ILE 96  ? A ILE 84  
85  1 Y 1 G TYR 97  ? A TYR 85  
86  1 Y 1 G ARG 98  ? A ARG 86  
87  1 Y 1 G ARG 99  ? A ARG 87  
88  1 Y 1 G VAL 100 ? A VAL 88  
89  1 Y 1 G ASP 101 ? A ASP 89  
90  1 Y 1 G GLY 102 ? A GLY 90  
91  1 Y 1 G LYS 103 ? A LYS 91  
92  1 Y 1 G TRP 104 ? A TRP 92  
93  1 Y 1 G ARG 105 ? A ARG 93  
94  1 Y 1 G ARG 106 ? A ARG 94  
95  1 Y 1 G GLU 107 ? A GLU 95  
96  1 Y 1 G LEU 108 ? A LEU 96  
97  1 Y 1 G ILE 109 ? A ILE 97  
98  1 Y 1 G LEU 110 ? A LEU 98  
99  1 Y 1 G TYR 111 ? A TYR 99  
100 1 Y 1 G ASP 112 ? A ASP 100 
101 1 Y 1 G LYS 113 ? A LYS 101 
102 1 Y 1 G GLU 114 ? A GLU 102 
103 1 Y 1 G GLU 115 ? A GLU 103 
104 1 Y 1 G ILE 116 ? A ILE 104 
105 1 Y 1 G ARG 117 ? A ARG 105 
106 1 Y 1 G ARG 118 ? A ARG 106 
107 1 Y 1 G ILE 119 ? A ILE 107 
108 1 Y 1 G TRP 120 ? A TRP 108 
109 1 Y 1 G ARG 121 ? A ARG 109 
110 1 Y 1 G GLN 122 ? A GLN 110 
111 1 Y 1 G ALA 123 ? A ALA 111 
112 1 Y 1 G ASN 124 ? A ASN 112 
113 1 Y 1 G ASN 125 ? A ASN 113 
114 1 Y 1 G GLY 126 ? A GLY 114 
115 1 Y 1 G ASP 127 ? A ASP 115 
116 1 Y 1 G ASP 128 ? A ASP 116 
117 1 Y 1 G ALA 129 ? A ALA 117 
118 1 Y 1 G THR 130 ? A THR 118 
119 1 Y 1 G ALA 131 ? A ALA 119 
120 1 Y 1 G GLY 132 ? A GLY 120 
121 1 Y 1 G LEU 133 ? A LEU 121 
122 1 Y 1 G THR 134 ? A THR 122 
123 1 Y 1 G HIS 135 ? A HIS 123 
124 1 Y 1 G MET 136 ? A MET 124 
125 1 Y 1 G MET 137 ? A MET 125 
126 1 Y 1 G ILE 138 ? A ILE 126 
127 1 Y 1 G TRP 139 ? A TRP 127 
128 1 Y 1 G HIS 140 ? A HIS 128 
129 1 Y 1 G SER 141 ? A SER 129 
130 1 Y 1 G ASN 142 ? A ASN 130 
131 1 Y 1 G LEU 143 ? A LEU 131 
132 1 Y 1 G ASN 144 ? A ASN 132 
133 1 Y 1 G ASP 145 ? A ASP 133 
134 1 Y 1 G ALA 146 ? A ALA 134 
135 1 Y 1 G THR 147 ? A THR 135 
136 1 Y 1 G TYR 148 ? A TYR 136 
137 1 Y 1 G GLN 149 ? A GLN 137 
138 1 Y 1 G ARG 150 ? A ARG 138 
139 1 Y 1 G THR 151 ? A THR 139 
140 1 Y 1 G ARG 152 ? A ARG 140 
141 1 Y 1 G ALA 153 ? A ALA 141 
142 1 Y 1 G LEU 154 ? A LEU 142 
143 1 Y 1 G VAL 155 ? A VAL 143 
144 1 Y 1 G ARG 156 ? A ARG 144 
145 1 Y 1 G THR 157 ? A THR 145 
146 1 Y 1 G GLY 158 ? A GLY 146 
147 1 Y 1 G MET 159 ? A MET 147 
148 1 Y 1 G ASP 160 ? A ASP 148 
149 1 Y 1 G PRO 161 ? A PRO 149 
150 1 Y 1 G ARG 162 ? A ARG 150 
151 1 Y 1 G MET 163 ? A MET 151 
152 1 Y 1 G CYS 164 ? A CYS 152 
153 1 Y 1 G SER 165 ? A SER 153 
154 1 Y 1 G LEU 166 ? A LEU 154 
155 1 Y 1 G MET 167 ? A MET 155 
156 1 Y 1 G GLN 168 ? A GLN 156 
157 1 Y 1 G GLY 169 ? A GLY 157 
158 1 Y 1 G SER 170 ? A SER 158 
159 1 Y 1 G THR 171 ? A THR 159 
160 1 Y 1 G LEU 172 ? A LEU 160 
161 1 Y 1 G PRO 173 ? A PRO 161 
162 1 Y 1 G ARG 174 ? A ARG 162 
163 1 Y 1 G ARG 175 ? A ARG 163 
164 1 Y 1 G SER 176 ? A SER 164 
165 1 Y 1 G GLY 177 ? A GLY 165 
166 1 Y 1 G ALA 178 ? A ALA 166 
167 1 Y 1 G ALA 179 ? A ALA 167 
168 1 Y 1 G GLY 180 ? A GLY 168 
169 1 Y 1 G ALA 181 ? A ALA 169 
170 1 Y 1 G ALA 182 ? A ALA 170 
171 1 Y 1 G VAL 183 ? A VAL 171 
172 1 Y 1 G LYS 184 ? A LYS 172 
173 1 Y 1 G GLY 185 ? A GLY 173 
174 1 Y 1 G VAL 186 ? A VAL 174 
175 1 Y 1 G GLY 187 ? A GLY 175 
176 1 Y 1 G THR 188 ? A THR 176 
177 1 Y 1 G MET 189 ? A MET 177 
178 1 Y 1 G VAL 190 ? A VAL 178 
179 1 Y 1 G MET 191 ? A MET 179 
180 1 Y 1 G GLU 192 ? A GLU 180 
181 1 Y 1 G LEU 193 ? A LEU 181 
182 1 Y 1 G ILE 194 ? A ILE 182 
183 1 Y 1 G ARG 195 ? A ARG 183 
184 1 Y 1 G MET 196 ? A MET 184 
185 1 Y 1 G ILE 197 ? A ILE 185 
186 1 Y 1 G LYS 198 ? A LYS 186 
187 1 Y 1 G ARG 199 ? A ARG 187 
188 1 Y 1 G GLY 200 ? A GLY 188 
189 1 Y 1 G ILE 201 ? A ILE 189 
190 1 Y 1 G ASN 202 ? A ASN 190 
191 1 Y 1 G ASP 203 ? A ASP 191 
192 1 Y 1 G ARG 204 ? A ARG 192 
193 1 Y 1 G ASN 205 ? A ASN 193 
194 1 Y 1 G PHE 206 ? A PHE 194 
195 1 Y 1 G TRP 207 ? A TRP 195 
196 1 Y 1 G ARG 208 ? A ARG 196 
197 1 Y 1 G GLY 209 ? A GLY 197 
198 1 Y 1 G GLU 210 ? A GLU 198 
199 1 Y 1 G ASN 211 ? A ASN 199 
200 1 Y 1 G GLY 212 ? A GLY 200 
201 1 Y 1 G ARG 213 ? A ARG 201 
202 1 Y 1 G ARG 214 ? A ARG 202 
203 1 Y 1 G THR 215 ? A THR 203 
204 1 Y 1 G ARG 216 ? A ARG 204 
205 1 Y 1 G ILE 217 ? A ILE 205 
206 1 Y 1 G ALA 218 ? A ALA 206 
207 1 Y 1 G TYR 219 ? A TYR 207 
208 1 Y 1 G GLU 220 ? A GLU 208 
209 1 Y 1 G ARG 221 ? A ARG 209 
210 1 Y 1 G MET 222 ? A MET 210 
211 1 Y 1 G CYS 223 ? A CYS 211 
212 1 Y 1 G ASN 224 ? A ASN 212 
213 1 Y 1 G ILE 225 ? A ILE 213 
214 1 Y 1 G LEU 226 ? A LEU 214 
215 1 Y 1 G LYS 227 ? A LYS 215 
216 1 Y 1 G GLY 228 ? A GLY 216 
217 1 Y 1 G LYS 229 ? A LYS 217 
218 1 Y 1 G PHE 230 ? A PHE 218 
219 1 Y 1 G GLN 231 ? A GLN 219 
220 1 Y 1 G THR 232 ? A THR 220 
221 1 Y 1 G ALA 233 ? A ALA 221 
222 1 Y 1 G ALA 234 ? A ALA 222 
223 1 Y 1 G GLN 235 ? A GLN 223 
224 1 Y 1 G ARG 236 ? A ARG 224 
225 1 Y 1 G THR 237 ? A THR 225 
226 1 Y 1 G MET 238 ? A MET 226 
227 1 Y 1 G VAL 239 ? A VAL 227 
228 1 Y 1 G ASP 240 ? A ASP 228 
229 1 Y 1 G GLN 241 ? A GLN 229 
230 1 Y 1 G VAL 242 ? A VAL 230 
231 1 Y 1 G ARG 243 ? A ARG 231 
232 1 Y 1 G GLU 244 ? A GLU 232 
233 1 Y 1 G SER 245 ? A SER 233 
234 1 Y 1 G ARG 246 ? A ARG 234 
235 1 Y 1 G ASN 247 ? A ASN 235 
236 1 Y 1 G PRO 248 ? A PRO 236 
237 1 Y 1 G GLY 249 ? A GLY 237 
238 1 Y 1 G ASN 250 ? A ASN 238 
239 1 Y 1 G ALA 251 ? A ALA 239 
240 1 Y 1 G GLU 252 ? A GLU 240 
241 1 Y 1 G PHE 253 ? A PHE 241 
242 1 Y 1 G GLU 254 ? A GLU 242 
243 1 Y 1 G ASP 255 ? A ASP 243 
244 1 Y 1 G LEU 256 ? A LEU 244 
245 1 Y 1 G ILE 257 ? A ILE 245 
246 1 Y 1 G PHE 258 ? A PHE 246 
247 1 Y 1 G LEU 259 ? A LEU 247 
248 1 Y 1 G ALA 260 ? A ALA 248 
249 1 Y 1 G ARG 261 ? A ARG 249 
250 1 Y 1 G SER 262 ? A SER 250 
251 1 Y 1 G ALA 263 ? A ALA 251 
252 1 Y 1 G LEU 264 ? A LEU 252 
253 1 Y 1 G ILE 265 ? A ILE 253 
254 1 Y 1 G LEU 266 ? A LEU 254 
255 1 Y 1 G ARG 267 ? A ARG 255 
256 1 Y 1 G GLY 268 ? A GLY 256 
257 1 Y 1 G SER 269 ? A SER 257 
258 1 Y 1 G VAL 270 ? A VAL 258 
259 1 Y 1 G ALA 271 ? A ALA 259 
260 1 Y 1 G HIS 272 ? A HIS 260 
261 1 Y 1 G LYS 273 ? A LYS 261 
262 1 Y 1 G SER 274 ? A SER 262 
263 1 Y 1 G CYS 275 ? A CYS 263 
264 1 Y 1 G LEU 276 ? A LEU 264 
265 1 Y 1 G PRO 277 ? A PRO 265 
266 1 Y 1 G ALA 278 ? A ALA 266 
267 1 Y 1 G CYS 279 ? A CYS 267 
268 1 Y 1 G VAL 280 ? A VAL 268 
269 1 Y 1 G TYR 281 ? A TYR 269 
270 1 Y 1 G GLY 282 ? A GLY 270 
271 1 Y 1 G SER 283 ? A SER 271 
272 1 Y 1 G ALA 284 ? A ALA 272 
273 1 Y 1 G VAL 285 ? A VAL 273 
274 1 Y 1 G ALA 286 ? A ALA 274 
275 1 Y 1 G SER 287 ? A SER 275 
276 1 Y 1 G GLY 288 ? A GLY 276 
277 1 Y 1 G TYR 289 ? A TYR 277 
278 1 Y 1 G ASP 290 ? A ASP 278 
279 1 Y 1 G PHE 291 ? A PHE 279 
280 1 Y 1 G GLU 292 ? A GLU 280 
281 1 Y 1 G ARG 293 ? A ARG 281 
282 1 Y 1 G GLU 294 ? A GLU 282 
283 1 Y 1 G GLY 295 ? A GLY 283 
284 1 Y 1 G TYR 296 ? A TYR 284 
285 1 Y 1 G SER 297 ? A SER 285 
286 1 Y 1 G LEU 298 ? A LEU 286 
287 1 Y 1 G VAL 299 ? A VAL 287 
288 1 Y 1 G GLY 300 ? A GLY 288 
289 1 Y 1 G ILE 301 ? A ILE 289 
290 1 Y 1 G ASP 302 ? A ASP 290 
291 1 Y 1 G PRO 303 ? A PRO 291 
292 1 Y 1 G PHE 304 ? A PHE 292 
293 1 Y 1 G ARG 305 ? A ARG 293 
294 1 Y 1 G LEU 306 ? A LEU 294 
295 1 Y 1 G LEU 307 ? A LEU 295 
296 1 Y 1 G GLN 308 ? A GLN 296 
297 1 Y 1 G ASN 309 ? A ASN 297 
298 1 Y 1 G SER 310 ? A SER 298 
299 1 Y 1 G GLN 311 ? A GLN 299 
300 1 Y 1 G VAL 312 ? A VAL 300 
301 1 Y 1 G TYR 313 ? A TYR 301 
302 1 Y 1 G SER 314 ? A SER 302 
303 1 Y 1 G LEU 315 ? A LEU 303 
304 1 Y 1 G ILE 316 ? A ILE 304 
305 1 Y 1 G ARG 317 ? A ARG 305 
306 1 Y 1 G PRO 318 ? A PRO 306 
307 1 Y 1 G ASN 319 ? A ASN 307 
308 1 Y 1 G GLU 320 ? A GLU 308 
309 1 Y 1 G ASN 321 ? A ASN 309 
310 1 Y 1 G PRO 322 ? A PRO 310 
311 1 Y 1 G ALA 323 ? A ALA 311 
312 1 Y 1 G HIS 324 ? A HIS 312 
313 1 Y 1 G LYS 325 ? A LYS 313 
314 1 Y 1 G SER 326 ? A SER 314 
315 1 Y 1 G GLN 327 ? A GLN 315 
316 1 Y 1 G LEU 328 ? A LEU 316 
317 1 Y 1 G VAL 329 ? A VAL 317 
318 1 Y 1 G TRP 330 ? A TRP 318 
319 1 Y 1 G MET 331 ? A MET 319 
320 1 Y 1 G ALA 332 ? A ALA 320 
321 1 Y 1 G CYS 333 ? A CYS 321 
322 1 Y 1 G HIS 334 ? A HIS 322 
323 1 Y 1 G SER 335 ? A SER 323 
324 1 Y 1 G ALA 336 ? A ALA 324 
325 1 Y 1 G ALA 337 ? A ALA 325 
326 1 Y 1 G PHE 338 ? A PHE 326 
327 1 Y 1 G GLU 339 ? A GLU 327 
328 1 Y 1 G ASP 340 ? A ASP 328 
329 1 Y 1 G LEU 341 ? A LEU 329 
330 1 Y 1 G ARG 342 ? A ARG 330 
331 1 Y 1 G VAL 343 ? A VAL 331 
332 1 Y 1 G SER 344 ? A SER 332 
333 1 Y 1 G SER 345 ? A SER 333 
334 1 Y 1 G PHE 346 ? A PHE 334 
335 1 Y 1 G ILE 347 ? A ILE 335 
336 1 Y 1 G ARG 348 ? A ARG 336 
337 1 Y 1 G GLY 349 ? A GLY 337 
338 1 Y 1 G THR 350 ? A THR 338 
339 1 Y 1 G LYS 351 ? A LYS 339 
340 1 Y 1 G VAL 352 ? A VAL 340 
341 1 Y 1 G VAL 353 ? A VAL 341 
342 1 Y 1 G PRO 354 ? A PRO 342 
343 1 Y 1 G ARG 355 ? A ARG 343 
344 1 Y 1 G GLY 356 ? A GLY 344 
345 1 Y 1 G LYS 357 ? A LYS 345 
346 1 Y 1 G LEU 358 ? A LEU 346 
347 1 Y 1 G SER 359 ? A SER 347 
348 1 Y 1 G THR 360 ? A THR 348 
349 1 Y 1 G ARG 361 ? A ARG 349 
350 1 Y 1 G GLY 362 ? A GLY 350 
351 1 Y 1 G VAL 363 ? A VAL 351 
352 1 Y 1 G GLN 364 ? A GLN 352 
353 1 Y 1 G ILE 365 ? A ILE 353 
354 1 Y 1 G ALA 366 ? A ALA 354 
355 1 Y 1 G SER 367 ? A SER 355 
356 1 Y 1 G ASN 368 ? A ASN 356 
357 1 Y 1 G GLU 369 ? A GLU 357 
358 1 Y 1 G ASN 370 ? A ASN 358 
359 1 Y 1 G MET 371 ? A MET 359 
360 1 Y 1 G GLU 372 ? A GLU 360 
361 1 Y 1 G THR 373 ? A THR 361 
362 1 Y 1 G MET 374 ? A MET 362 
363 1 Y 1 G GLU 375 ? A GLU 363 
364 1 Y 1 G SER 376 ? A SER 364 
365 1 Y 1 G SER 377 ? A SER 365 
366 1 Y 1 G THR 378 ? A THR 366 
367 1 Y 1 G LEU 379 ? A LEU 367 
368 1 Y 1 G GLU 380 ? A GLU 368 
369 1 Y 1 G LEU 381 ? A LEU 369 
370 1 Y 1 G ARG 382 ? A ARG 370 
371 1 Y 1 G SER 383 ? A SER 371 
372 1 Y 1 G ARG 384 ? A ARG 372 
373 1 Y 1 G TYR 385 ? A TYR 373 
374 1 Y 1 G TRP 386 ? A TRP 374 
375 1 Y 1 G ALA 387 ? A ALA 375 
376 1 Y 1 G ILE 388 ? A ILE 376 
377 1 Y 1 G ARG 389 ? A ARG 377 
378 1 Y 1 G THR 390 ? A THR 378 
379 1 Y 1 G ARG 391 ? A ARG 379 
380 1 Y 1 G SER 392 ? A SER 380 
381 1 Y 1 G GLY 393 ? A GLY 381 
382 1 Y 1 G GLY 394 ? A GLY 382 
383 1 Y 1 G ASN 395 ? A ASN 383 
384 1 Y 1 G THR 396 ? A THR 384 
385 1 Y 1 G ASN 397 ? A ASN 385 
386 1 Y 1 G GLN 398 ? A GLN 386 
387 1 Y 1 G GLN 399 ? A GLN 387 
388 1 Y 1 G ARG 400 ? A ARG 388 
389 1 Y 1 G ALA 401 ? A ALA 389 
390 1 Y 1 G SER 402 ? A SER 390 
391 1 Y 1 G SER 403 ? A SER 391 
392 1 Y 1 G THR 430 ? A THR 418 
393 1 Y 1 G GLY 431 ? A GLY 419 
394 1 Y 1 G ASN 432 ? A ASN 420 
395 1 Y 1 G THR 433 ? A THR 421 
396 1 Y 1 G GLU 434 ? A GLU 422 
397 1 Y 1 G GLY 435 ? A GLY 423 
398 1 Y 1 G ARG 436 ? A ARG 424 
399 1 Y 1 G THR 437 ? A THR 425 
400 1 Y 1 G SER 438 ? A SER 426 
401 1 Y 1 G ASP 439 ? A ASP 427 
402 1 Y 1 G MET 440 ? A MET 428 
403 1 Y 1 G ARG 441 ? A ARG 429 
404 1 Y 1 G THR 442 ? A THR 430 
405 1 Y 1 G GLU 443 ? A GLU 431 
406 1 Y 1 G ILE 444 ? A ILE 432 
407 1 Y 1 G ILE 445 ? A ILE 433 
408 1 Y 1 G ARG 446 ? A ARG 434 
409 1 Y 1 G LEU 447 ? A LEU 435 
410 1 Y 1 G MET 448 ? A MET 436 
411 1 Y 1 G GLU 449 ? A GLU 437 
412 1 Y 1 G SER 450 ? A SER 438 
413 1 Y 1 G ALA 451 ? A ALA 439 
414 1 Y 1 G ARG 452 ? A ARG 440 
415 1 Y 1 G PRO 453 ? A PRO 441 
416 1 Y 1 G GLU 454 ? A GLU 442 
417 1 Y 1 G ASP 455 ? A ASP 443 
418 1 Y 1 G VAL 456 ? A VAL 444 
419 1 Y 1 G SER 457 ? A SER 445 
420 1 Y 1 G PHE 458 ? A PHE 446 
421 1 Y 1 G GLN 459 ? A GLN 447 
422 1 Y 1 G GLY 460 ? A GLY 448 
423 1 Y 1 G ARG 461 ? A ARG 449 
424 1 Y 1 G GLY 462 ? A GLY 450 
425 1 Y 1 G VAL 463 ? A VAL 451 
426 1 Y 1 G PHE 464 ? A PHE 452 
427 1 Y 1 G GLU 465 ? A GLU 453 
428 1 Y 1 G LEU 466 ? A LEU 454 
429 1 Y 1 G SER 467 ? A SER 455 
430 1 Y 1 G ASP 468 ? A ASP 456 
431 1 Y 1 G GLU 469 ? A GLU 457 
432 1 Y 1 G LYS 470 ? A LYS 458 
433 1 Y 1 G ALA 471 ? A ALA 459 
434 1 Y 1 G THR 472 ? A THR 460 
435 1 Y 1 G SER 473 ? A SER 461 
436 1 Y 1 G PRO 474 ? A PRO 462 
437 1 Y 1 G ILE 475 ? A ILE 463 
438 1 Y 1 G VAL 476 ? A VAL 464 
439 1 Y 1 G PRO 477 ? A PRO 465 
440 1 Y 1 G SER 478 ? A SER 466 
441 1 Y 1 G PHE 479 ? A PHE 467 
442 1 Y 1 G ASP 480 ? A ASP 468 
443 1 Y 1 G MET 481 ? A MET 469 
444 1 Y 1 G SER 482 ? A SER 470 
445 1 Y 1 G ASN 483 ? A ASN 471 
446 1 Y 1 G GLU 484 ? A GLU 472 
447 1 Y 1 G GLY 485 ? A GLY 473 
448 1 Y 1 G SER 486 ? A SER 474 
449 1 Y 1 G TYR 487 ? A TYR 475 
450 1 Y 1 G PHE 488 ? A PHE 476 
451 1 Y 1 G PHE 489 ? A PHE 477 
452 1 Y 1 G GLY 490 ? A GLY 478 
453 1 Y 1 G ASP 491 ? A ASP 479 
454 1 Y 1 G ASN 492 ? A ASN 480 
455 1 Y 1 G ALA 493 ? A ALA 481 
456 1 Y 1 G GLU 494 ? A GLU 482 
457 1 Y 1 G GLU 495 ? A GLU 483 
458 1 Y 1 G TYR 496 ? A TYR 484 
459 1 Y 1 G ASP 497 ? A ASP 485 
460 1 Y 1 G ASN 498 ? A ASN 486 
461 1 Y 1 G LEU 499 ? A LEU 487 
462 1 Y 1 G GLU 500 ? A GLU 488 
463 1 Y 1 G HIS 501 ? A HIS 489 
464 1 Y 1 G HIS 502 ? A HIS 490 
465 1 Y 1 G HIS 503 ? A HIS 491 
466 1 Y 1 G HIS 504 ? A HIS 492 
467 1 Y 1 G HIS 505 ? A HIS 493 
468 1 Y 1 G HIS 506 ? A HIS 494 
469 1 Y 1 D U   7   ? B U   1   
470 1 Y 1 D U   19  ? B U   13  
471 1 Y 1 D C   20  ? B C   14  
472 1 Y 1 D U   21  ? B U   15  
473 1 Y 1 D C   22  ? B C   16  
474 1 Y 1 D U   23  ? B U   17  
475 1 Y 1 D C   24  ? B C   18  
476 1 Y 1 F C   8   ? D C   8   
477 1 Y 1 F U   9   ? D U   9   
478 1 Y 1 F C   10  ? D C   10  
479 1 Y 1 F U   11  ? D U   11  
480 1 Y 1 F C   12  ? D C   12  
481 1 Y 1 F U   13  ? D U   13  
482 1 Y 1 F C   14  ? D C   14  
483 1 Y 1 F U   15  ? D U   15  
484 1 Y 1 F C   16  ? D C   16  
485 1 Y 1 F U   17  ? D U   17  
486 1 Y 1 F C   18  ? D C   18  
487 1 Y 1 B HIS 13  ? E HIS 1   
488 1 Y 1 B MET 14  ? E MET 2   
489 1 Y 1 B THR 396 ? E THR 384 
490 1 Y 1 B ASN 397 ? E ASN 385 
491 1 Y 1 B GLN 398 ? E GLN 386 
492 1 Y 1 B GLN 399 ? E GLN 387 
493 1 Y 1 B ARG 400 ? E ARG 388 
494 1 Y 1 B ALA 401 ? E ALA 389 
495 1 Y 1 B SER 402 ? E SER 390 
496 1 Y 1 B SER 403 ? E SER 391 
497 1 Y 1 B THR 430 ? E THR 418 
498 1 Y 1 B GLY 431 ? E GLY 419 
499 1 Y 1 B ASN 432 ? E ASN 420 
500 1 Y 1 B THR 433 ? E THR 421 
501 1 Y 1 B GLU 434 ? E GLU 422 
502 1 Y 1 B GLY 435 ? E GLY 423 
503 1 Y 1 B ARG 436 ? E ARG 424 
504 1 Y 1 B THR 437 ? E THR 425 
505 1 Y 1 B SER 438 ? E SER 426 
506 1 Y 1 B ASP 439 ? E ASP 427 
507 1 Y 1 B ASP 480 ? E ASP 468 
508 1 Y 1 B MET 481 ? E MET 469 
509 1 Y 1 B SER 482 ? E SER 470 
510 1 Y 1 B ASN 483 ? E ASN 471 
511 1 Y 1 B ASP 491 ? E ASP 479 
512 1 Y 1 B ASN 492 ? E ASN 480 
513 1 Y 1 B ALA 493 ? E ALA 481 
514 1 Y 1 B GLU 494 ? E GLU 482 
515 1 Y 1 B GLU 495 ? E GLU 483 
516 1 Y 1 B TYR 496 ? E TYR 484 
517 1 Y 1 B ASP 497 ? E ASP 485 
518 1 Y 1 B ASN 498 ? E ASN 486 
519 1 Y 1 B LEU 499 ? E LEU 487 
520 1 Y 1 B GLU 500 ? E GLU 488 
521 1 Y 1 B HIS 501 ? E HIS 489 
522 1 Y 1 B HIS 502 ? E HIS 490 
523 1 Y 1 B HIS 503 ? E HIS 491 
524 1 Y 1 B HIS 504 ? E HIS 492 
525 1 Y 1 B HIS 505 ? E HIS 493 
526 1 Y 1 B HIS 506 ? E HIS 494 
527 1 Y 1 A HIS 13  ? F HIS 1   
528 1 Y 1 A MET 14  ? F MET 2   
529 1 Y 1 A THR 396 ? F THR 384 
530 1 Y 1 A ASN 397 ? F ASN 385 
531 1 Y 1 A GLN 398 ? F GLN 386 
532 1 Y 1 A GLN 399 ? F GLN 387 
533 1 Y 1 A ARG 400 ? F ARG 388 
534 1 Y 1 A ALA 401 ? F ALA 389 
535 1 Y 1 A SER 402 ? F SER 390 
536 1 Y 1 A SER 403 ? F SER 391 
537 1 Y 1 A GLY 404 ? F GLY 392 
538 1 Y 1 A GLN 405 ? F GLN 393 
539 1 Y 1 A ILE 406 ? F ILE 394 
540 1 Y 1 A SER 407 ? F SER 395 
541 1 Y 1 A ILE 408 ? F ILE 396 
542 1 Y 1 A GLN 409 ? F GLN 397 
543 1 Y 1 A PRO 410 ? F PRO 398 
544 1 Y 1 A THR 411 ? F THR 399 
545 1 Y 1 A PHE 412 ? F PHE 400 
546 1 Y 1 A SER 413 ? F SER 401 
547 1 Y 1 A VAL 414 ? F VAL 402 
548 1 Y 1 A GLN 415 ? F GLN 403 
549 1 Y 1 A ARG 416 ? F ARG 404 
550 1 Y 1 A ASN 417 ? F ASN 405 
551 1 Y 1 A LEU 418 ? F LEU 406 
552 1 Y 1 A PRO 419 ? F PRO 407 
553 1 Y 1 A PHE 420 ? F PHE 408 
554 1 Y 1 A ASP 421 ? F ASP 409 
555 1 Y 1 A ARG 422 ? F ARG 410 
556 1 Y 1 A PRO 423 ? F PRO 411 
557 1 Y 1 A THR 424 ? F THR 412 
558 1 Y 1 A ILE 425 ? F ILE 413 
559 1 Y 1 A MET 426 ? F MET 414 
560 1 Y 1 A ALA 427 ? F ALA 415 
561 1 Y 1 A ALA 428 ? F ALA 416 
562 1 Y 1 A PHE 429 ? F PHE 417 
563 1 Y 1 A THR 430 ? F THR 418 
564 1 Y 1 A GLY 431 ? F GLY 419 
565 1 Y 1 A ASN 432 ? F ASN 420 
566 1 Y 1 A THR 433 ? F THR 421 
567 1 Y 1 A GLU 434 ? F GLU 422 
568 1 Y 1 A GLY 435 ? F GLY 423 
569 1 Y 1 A ARG 436 ? F ARG 424 
570 1 Y 1 A THR 437 ? F THR 425 
571 1 Y 1 A SER 438 ? F SER 426 
572 1 Y 1 A ASP 439 ? F ASP 427 
573 1 Y 1 A ASP 480 ? F ASP 468 
574 1 Y 1 A MET 481 ? F MET 469 
575 1 Y 1 A SER 482 ? F SER 470 
576 1 Y 1 A ASN 483 ? F ASN 471 
577 1 Y 1 A ASP 491 ? F ASP 479 
578 1 Y 1 A ASN 492 ? F ASN 480 
579 1 Y 1 A ALA 493 ? F ALA 481 
580 1 Y 1 A GLU 494 ? F GLU 482 
581 1 Y 1 A GLU 495 ? F GLU 483 
582 1 Y 1 A TYR 496 ? F TYR 484 
583 1 Y 1 A ASP 497 ? F ASP 485 
584 1 Y 1 A ASN 498 ? F ASN 486 
585 1 Y 1 A LEU 499 ? F LEU 487 
586 1 Y 1 A GLU 500 ? F GLU 488 
587 1 Y 1 A HIS 501 ? F HIS 489 
588 1 Y 1 A HIS 502 ? F HIS 490 
589 1 Y 1 A HIS 503 ? F HIS 491 
590 1 Y 1 A HIS 504 ? F HIS 492 
591 1 Y 1 A HIS 505 ? F HIS 493 
592 1 Y 1 A HIS 506 ? F HIS 494 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1IJK C1     C N N 1   
A1IJK C2     C N R 2   
A1IJK C3     C N N 3   
A1IJK C6     C N N 4   
A1IJK C7     C N N 5   
A1IJK O4     O N N 6   
A1IJK O5     O N N 7   
A1IJK C8     C N N 8   
A1IJK C10    C N N 9   
A1IJK N9     N N N 10  
A1IJK C33    C N N 11  
A1IJK C34    C N N 12  
A1IJK C11    C Y N 13  
A1IJK C12    C Y N 14  
A1IJK C13    C Y N 15  
A1IJK C14    C Y N 16  
A1IJK C15    C Y N 17  
A1IJK C16    C Y N 18  
A1IJK C17    C N N 19  
A1IJK C20    C Y N 20  
A1IJK C21    C Y N 21  
A1IJK C22    C Y N 22  
A1IJK C24    C Y N 23  
A1IJK C25    C Y N 24  
A1IJK C27    C N N 25  
A1IJK C28    C N N 26  
A1IJK C29    C N N 27  
A1IJK C30    C N N 28  
A1IJK C31    C N N 29  
A1IJK C32    C N N 30  
A1IJK O18    O N N 31  
A1IJK O19    O N N 32  
A1IJK O23    O Y N 33  
A1IJK O26    O N N 34  
A1IJK O35    O N N 35  
A1IJK O36    O N N 36  
A1IJK H1     H N N 37  
A1IJK H2     H N N 38  
A1IJK H3     H N N 39  
A1IJK H4     H N N 40  
A1IJK H5     H N N 41  
A1IJK H6     H N N 42  
A1IJK H7     H N N 43  
A1IJK H8     H N N 44  
A1IJK H9     H N N 45  
A1IJK H10    H N N 46  
A1IJK H11    H N N 47  
A1IJK H12    H N N 48  
A1IJK H13    H N N 49  
A1IJK H14    H N N 50  
A1IJK H15    H N N 51  
A1IJK H16    H N N 52  
A1IJK H17    H N N 53  
A1IJK H18    H N N 54  
A1IJK H19    H N N 55  
A1IJK H20    H N N 56  
A1IJK H21    H N N 57  
A1IJK H22    H N N 58  
A1IJK H23    H N N 59  
A1IJK H24    H N N 60  
A1IJK H25    H N N 61  
A1IJK H26    H N N 62  
A1IJK H27    H N N 63  
ALA   N      N N N 64  
ALA   CA     C N S 65  
ALA   C      C N N 66  
ALA   O      O N N 67  
ALA   CB     C N N 68  
ALA   OXT    O N N 69  
ALA   H      H N N 70  
ALA   H2     H N N 71  
ALA   HA     H N N 72  
ALA   HB1    H N N 73  
ALA   HB2    H N N 74  
ALA   HB3    H N N 75  
ALA   HXT    H N N 76  
ARG   N      N N N 77  
ARG   CA     C N S 78  
ARG   C      C N N 79  
ARG   O      O N N 80  
ARG   CB     C N N 81  
ARG   CG     C N N 82  
ARG   CD     C N N 83  
ARG   NE     N N N 84  
ARG   CZ     C N N 85  
ARG   NH1    N N N 86  
ARG   NH2    N N N 87  
ARG   OXT    O N N 88  
ARG   H      H N N 89  
ARG   H2     H N N 90  
ARG   HA     H N N 91  
ARG   HB2    H N N 92  
ARG   HB3    H N N 93  
ARG   HG2    H N N 94  
ARG   HG3    H N N 95  
ARG   HD2    H N N 96  
ARG   HD3    H N N 97  
ARG   HE     H N N 98  
ARG   HH11   H N N 99  
ARG   HH12   H N N 100 
ARG   HH21   H N N 101 
ARG   HH22   H N N 102 
ARG   HXT    H N N 103 
ASN   N      N N N 104 
ASN   CA     C N S 105 
ASN   C      C N N 106 
ASN   O      O N N 107 
ASN   CB     C N N 108 
ASN   CG     C N N 109 
ASN   OD1    O N N 110 
ASN   ND2    N N N 111 
ASN   OXT    O N N 112 
ASN   H      H N N 113 
ASN   H2     H N N 114 
ASN   HA     H N N 115 
ASN   HB2    H N N 116 
ASN   HB3    H N N 117 
ASN   HD21   H N N 118 
ASN   HD22   H N N 119 
ASN   HXT    H N N 120 
ASP   N      N N N 121 
ASP   CA     C N S 122 
ASP   C      C N N 123 
ASP   O      O N N 124 
ASP   CB     C N N 125 
ASP   CG     C N N 126 
ASP   OD1    O N N 127 
ASP   OD2    O N N 128 
ASP   OXT    O N N 129 
ASP   H      H N N 130 
ASP   H2     H N N 131 
ASP   HA     H N N 132 
ASP   HB2    H N N 133 
ASP   HB3    H N N 134 
ASP   HD2    H N N 135 
ASP   HXT    H N N 136 
C     OP3    O N N 137 
C     P      P N N 138 
C     OP1    O N N 139 
C     OP2    O N N 140 
C     "O5'"  O N N 141 
C     "C5'"  C N N 142 
C     "C4'"  C N R 143 
C     "O4'"  O N N 144 
C     "C3'"  C N S 145 
C     "O3'"  O N N 146 
C     "C2'"  C N R 147 
C     "O2'"  O N N 148 
C     "C1'"  C N R 149 
C     N1     N N N 150 
C     C2     C N N 151 
C     O2     O N N 152 
C     N3     N N N 153 
C     C4     C N N 154 
C     N4     N N N 155 
C     C5     C N N 156 
C     C6     C N N 157 
C     HOP3   H N N 158 
C     HOP2   H N N 159 
C     "H5'"  H N N 160 
C     "H5''" H N N 161 
C     "H4'"  H N N 162 
C     "H3'"  H N N 163 
C     "HO3'" H N N 164 
C     "H2'"  H N N 165 
C     "HO2'" H N N 166 
C     "H1'"  H N N 167 
C     H41    H N N 168 
C     H42    H N N 169 
C     H5     H N N 170 
C     H6     H N N 171 
CYS   N      N N N 172 
CYS   CA     C N R 173 
CYS   C      C N N 174 
CYS   O      O N N 175 
CYS   CB     C N N 176 
CYS   SG     S N N 177 
CYS   OXT    O N N 178 
CYS   H      H N N 179 
CYS   H2     H N N 180 
CYS   HA     H N N 181 
CYS   HB2    H N N 182 
CYS   HB3    H N N 183 
CYS   HG     H N N 184 
CYS   HXT    H N N 185 
GLN   N      N N N 186 
GLN   CA     C N S 187 
GLN   C      C N N 188 
GLN   O      O N N 189 
GLN   CB     C N N 190 
GLN   CG     C N N 191 
GLN   CD     C N N 192 
GLN   OE1    O N N 193 
GLN   NE2    N N N 194 
GLN   OXT    O N N 195 
GLN   H      H N N 196 
GLN   H2     H N N 197 
GLN   HA     H N N 198 
GLN   HB2    H N N 199 
GLN   HB3    H N N 200 
GLN   HG2    H N N 201 
GLN   HG3    H N N 202 
GLN   HE21   H N N 203 
GLN   HE22   H N N 204 
GLN   HXT    H N N 205 
GLU   N      N N N 206 
GLU   CA     C N S 207 
GLU   C      C N N 208 
GLU   O      O N N 209 
GLU   CB     C N N 210 
GLU   CG     C N N 211 
GLU   CD     C N N 212 
GLU   OE1    O N N 213 
GLU   OE2    O N N 214 
GLU   OXT    O N N 215 
GLU   H      H N N 216 
GLU   H2     H N N 217 
GLU   HA     H N N 218 
GLU   HB2    H N N 219 
GLU   HB3    H N N 220 
GLU   HG2    H N N 221 
GLU   HG3    H N N 222 
GLU   HE2    H N N 223 
GLU   HXT    H N N 224 
GLY   N      N N N 225 
GLY   CA     C N N 226 
GLY   C      C N N 227 
GLY   O      O N N 228 
GLY   OXT    O N N 229 
GLY   H      H N N 230 
GLY   H2     H N N 231 
GLY   HA2    H N N 232 
GLY   HA3    H N N 233 
GLY   HXT    H N N 234 
HIS   N      N N N 235 
HIS   CA     C N S 236 
HIS   C      C N N 237 
HIS   O      O N N 238 
HIS   CB     C N N 239 
HIS   CG     C Y N 240 
HIS   ND1    N Y N 241 
HIS   CD2    C Y N 242 
HIS   CE1    C Y N 243 
HIS   NE2    N Y N 244 
HIS   OXT    O N N 245 
HIS   H      H N N 246 
HIS   H2     H N N 247 
HIS   HA     H N N 248 
HIS   HB2    H N N 249 
HIS   HB3    H N N 250 
HIS   HD1    H N N 251 
HIS   HD2    H N N 252 
HIS   HE1    H N N 253 
HIS   HE2    H N N 254 
HIS   HXT    H N N 255 
ILE   N      N N N 256 
ILE   CA     C N S 257 
ILE   C      C N N 258 
ILE   O      O N N 259 
ILE   CB     C N S 260 
ILE   CG1    C N N 261 
ILE   CG2    C N N 262 
ILE   CD1    C N N 263 
ILE   OXT    O N N 264 
ILE   H      H N N 265 
ILE   H2     H N N 266 
ILE   HA     H N N 267 
ILE   HB     H N N 268 
ILE   HG12   H N N 269 
ILE   HG13   H N N 270 
ILE   HG21   H N N 271 
ILE   HG22   H N N 272 
ILE   HG23   H N N 273 
ILE   HD11   H N N 274 
ILE   HD12   H N N 275 
ILE   HD13   H N N 276 
ILE   HXT    H N N 277 
LEU   N      N N N 278 
LEU   CA     C N S 279 
LEU   C      C N N 280 
LEU   O      O N N 281 
LEU   CB     C N N 282 
LEU   CG     C N N 283 
LEU   CD1    C N N 284 
LEU   CD2    C N N 285 
LEU   OXT    O N N 286 
LEU   H      H N N 287 
LEU   H2     H N N 288 
LEU   HA     H N N 289 
LEU   HB2    H N N 290 
LEU   HB3    H N N 291 
LEU   HG     H N N 292 
LEU   HD11   H N N 293 
LEU   HD12   H N N 294 
LEU   HD13   H N N 295 
LEU   HD21   H N N 296 
LEU   HD22   H N N 297 
LEU   HD23   H N N 298 
LEU   HXT    H N N 299 
LYS   N      N N N 300 
LYS   CA     C N S 301 
LYS   C      C N N 302 
LYS   O      O N N 303 
LYS   CB     C N N 304 
LYS   CG     C N N 305 
LYS   CD     C N N 306 
LYS   CE     C N N 307 
LYS   NZ     N N N 308 
LYS   OXT    O N N 309 
LYS   H      H N N 310 
LYS   H2     H N N 311 
LYS   HA     H N N 312 
LYS   HB2    H N N 313 
LYS   HB3    H N N 314 
LYS   HG2    H N N 315 
LYS   HG3    H N N 316 
LYS   HD2    H N N 317 
LYS   HD3    H N N 318 
LYS   HE2    H N N 319 
LYS   HE3    H N N 320 
LYS   HZ1    H N N 321 
LYS   HZ2    H N N 322 
LYS   HZ3    H N N 323 
LYS   HXT    H N N 324 
MET   N      N N N 325 
MET   CA     C N S 326 
MET   C      C N N 327 
MET   O      O N N 328 
MET   CB     C N N 329 
MET   CG     C N N 330 
MET   SD     S N N 331 
MET   CE     C N N 332 
MET   OXT    O N N 333 
MET   H      H N N 334 
MET   H2     H N N 335 
MET   HA     H N N 336 
MET   HB2    H N N 337 
MET   HB3    H N N 338 
MET   HG2    H N N 339 
MET   HG3    H N N 340 
MET   HE1    H N N 341 
MET   HE2    H N N 342 
MET   HE3    H N N 343 
MET   HXT    H N N 344 
PHE   N      N N N 345 
PHE   CA     C N S 346 
PHE   C      C N N 347 
PHE   O      O N N 348 
PHE   CB     C N N 349 
PHE   CG     C Y N 350 
PHE   CD1    C Y N 351 
PHE   CD2    C Y N 352 
PHE   CE1    C Y N 353 
PHE   CE2    C Y N 354 
PHE   CZ     C Y N 355 
PHE   OXT    O N N 356 
PHE   H      H N N 357 
PHE   H2     H N N 358 
PHE   HA     H N N 359 
PHE   HB2    H N N 360 
PHE   HB3    H N N 361 
PHE   HD1    H N N 362 
PHE   HD2    H N N 363 
PHE   HE1    H N N 364 
PHE   HE2    H N N 365 
PHE   HZ     H N N 366 
PHE   HXT    H N N 367 
PRO   N      N N N 368 
PRO   CA     C N S 369 
PRO   C      C N N 370 
PRO   O      O N N 371 
PRO   CB     C N N 372 
PRO   CG     C N N 373 
PRO   CD     C N N 374 
PRO   OXT    O N N 375 
PRO   H      H N N 376 
PRO   HA     H N N 377 
PRO   HB2    H N N 378 
PRO   HB3    H N N 379 
PRO   HG2    H N N 380 
PRO   HG3    H N N 381 
PRO   HD2    H N N 382 
PRO   HD3    H N N 383 
PRO   HXT    H N N 384 
SER   N      N N N 385 
SER   CA     C N S 386 
SER   C      C N N 387 
SER   O      O N N 388 
SER   CB     C N N 389 
SER   OG     O N N 390 
SER   OXT    O N N 391 
SER   H      H N N 392 
SER   H2     H N N 393 
SER   HA     H N N 394 
SER   HB2    H N N 395 
SER   HB3    H N N 396 
SER   HG     H N N 397 
SER   HXT    H N N 398 
THR   N      N N N 399 
THR   CA     C N S 400 
THR   C      C N N 401 
THR   O      O N N 402 
THR   CB     C N R 403 
THR   OG1    O N N 404 
THR   CG2    C N N 405 
THR   OXT    O N N 406 
THR   H      H N N 407 
THR   H2     H N N 408 
THR   HA     H N N 409 
THR   HB     H N N 410 
THR   HG1    H N N 411 
THR   HG21   H N N 412 
THR   HG22   H N N 413 
THR   HG23   H N N 414 
THR   HXT    H N N 415 
TRP   N      N N N 416 
TRP   CA     C N S 417 
TRP   C      C N N 418 
TRP   O      O N N 419 
TRP   CB     C N N 420 
TRP   CG     C Y N 421 
TRP   CD1    C Y N 422 
TRP   CD2    C Y N 423 
TRP   NE1    N Y N 424 
TRP   CE2    C Y N 425 
TRP   CE3    C Y N 426 
TRP   CZ2    C Y N 427 
TRP   CZ3    C Y N 428 
TRP   CH2    C Y N 429 
TRP   OXT    O N N 430 
TRP   H      H N N 431 
TRP   H2     H N N 432 
TRP   HA     H N N 433 
TRP   HB2    H N N 434 
TRP   HB3    H N N 435 
TRP   HD1    H N N 436 
TRP   HE1    H N N 437 
TRP   HE3    H N N 438 
TRP   HZ2    H N N 439 
TRP   HZ3    H N N 440 
TRP   HH2    H N N 441 
TRP   HXT    H N N 442 
TYR   N      N N N 443 
TYR   CA     C N S 444 
TYR   C      C N N 445 
TYR   O      O N N 446 
TYR   CB     C N N 447 
TYR   CG     C Y N 448 
TYR   CD1    C Y N 449 
TYR   CD2    C Y N 450 
TYR   CE1    C Y N 451 
TYR   CE2    C Y N 452 
TYR   CZ     C Y N 453 
TYR   OH     O N N 454 
TYR   OXT    O N N 455 
TYR   H      H N N 456 
TYR   H2     H N N 457 
TYR   HA     H N N 458 
TYR   HB2    H N N 459 
TYR   HB3    H N N 460 
TYR   HD1    H N N 461 
TYR   HD2    H N N 462 
TYR   HE1    H N N 463 
TYR   HE2    H N N 464 
TYR   HH     H N N 465 
TYR   HXT    H N N 466 
U     OP3    O N N 467 
U     P      P N N 468 
U     OP1    O N N 469 
U     OP2    O N N 470 
U     "O5'"  O N N 471 
U     "C5'"  C N N 472 
U     "C4'"  C N R 473 
U     "O4'"  O N N 474 
U     "C3'"  C N S 475 
U     "O3'"  O N N 476 
U     "C2'"  C N R 477 
U     "O2'"  O N N 478 
U     "C1'"  C N R 479 
U     N1     N N N 480 
U     C2     C N N 481 
U     O2     O N N 482 
U     N3     N N N 483 
U     C4     C N N 484 
U     O4     O N N 485 
U     C5     C N N 486 
U     C6     C N N 487 
U     HOP3   H N N 488 
U     HOP2   H N N 489 
U     "H5'"  H N N 490 
U     "H5''" H N N 491 
U     "H4'"  H N N 492 
U     "H3'"  H N N 493 
U     "HO3'" H N N 494 
U     "H2'"  H N N 495 
U     "HO2'" H N N 496 
U     "H1'"  H N N 497 
U     H3     H N N 498 
U     H5     H N N 499 
U     H6     H N N 500 
VAL   N      N N N 501 
VAL   CA     C N S 502 
VAL   C      C N N 503 
VAL   O      O N N 504 
VAL   CB     C N N 505 
VAL   CG1    C N N 506 
VAL   CG2    C N N 507 
VAL   OXT    O N N 508 
VAL   H      H N N 509 
VAL   H2     H N N 510 
VAL   HA     H N N 511 
VAL   HB     H N N 512 
VAL   HG11   H N N 513 
VAL   HG12   H N N 514 
VAL   HG13   H N N 515 
VAL   HG21   H N N 516 
VAL   HG22   H N N 517 
VAL   HG23   H N N 518 
VAL   HXT    H N N 519 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1IJK C2    O5     sing N N 1   
A1IJK C2    C1     sing N N 2   
A1IJK C2    C3     sing N N 3   
A1IJK O19   C17    doub N N 4   
A1IJK C13   C12    doub Y N 5   
A1IJK C13   C14    sing Y N 6   
A1IJK C12   C11    sing Y N 7   
A1IJK O4    C3     sing N N 8   
A1IJK O4    C6     sing N N 9   
A1IJK N9    C8     sing N N 10  
A1IJK N9    C10    sing N N 11  
A1IJK C8    C7     sing N N 12  
A1IJK C17   C14    sing N N 13  
A1IJK C17   O18    sing N N 14  
A1IJK C14   C15    doub Y N 15  
A1IJK C11   C10    sing N N 16  
A1IJK C11   C16    doub Y N 17  
A1IJK C10   O26    doub N N 18  
A1IJK C6    C7     sing N N 19  
A1IJK C15   C16    sing Y N 20  
A1IJK C15   C20    sing N N 21  
A1IJK C29   C30    doub N N 22  
A1IJK C29   C28    sing N N 23  
A1IJK C30   C21    sing N N 24  
A1IJK C20   C21    doub Y N 25  
A1IJK C20   C25    sing Y N 26  
A1IJK C21   C22    sing Y N 27  
A1IJK C28   O35    doub N N 28  
A1IJK C28   C27    sing N N 29  
A1IJK C22   C27    sing N N 30  
A1IJK C22   O23    doub Y N 31  
A1IJK C25   C34    sing N N 32  
A1IJK C25   C24    doub Y N 33  
A1IJK C34   C33    doub N N 34  
A1IJK O23   C24    sing Y N 35  
A1IJK C24   C31    sing N N 36  
A1IJK C33   C32    sing N N 37  
A1IJK C31   C32    sing N N 38  
A1IJK C32   O36    doub N N 39  
A1IJK C1    H1     sing N N 40  
A1IJK C1    H2     sing N N 41  
A1IJK C1    H3     sing N N 42  
A1IJK C2    H4     sing N N 43  
A1IJK C3    H5     sing N N 44  
A1IJK C3    H6     sing N N 45  
A1IJK C6    H7     sing N N 46  
A1IJK C6    H8     sing N N 47  
A1IJK C7    H9     sing N N 48  
A1IJK C7    H10    sing N N 49  
A1IJK O5    H11    sing N N 50  
A1IJK C8    H12    sing N N 51  
A1IJK C8    H13    sing N N 52  
A1IJK N9    H14    sing N N 53  
A1IJK C33   H15    sing N N 54  
A1IJK C34   H16    sing N N 55  
A1IJK C12   H17    sing N N 56  
A1IJK C13   H18    sing N N 57  
A1IJK C16   H19    sing N N 58  
A1IJK C27   H20    sing N N 59  
A1IJK C27   H21    sing N N 60  
A1IJK C29   H22    sing N N 61  
A1IJK C30   H23    sing N N 62  
A1IJK C31   H24    sing N N 63  
A1IJK C31   H25    sing N N 64  
A1IJK O18   H26    sing N N 65  
A1IJK O23   H27    sing N N 66  
ALA   N     CA     sing N N 67  
ALA   N     H      sing N N 68  
ALA   N     H2     sing N N 69  
ALA   CA    C      sing N N 70  
ALA   CA    CB     sing N N 71  
ALA   CA    HA     sing N N 72  
ALA   C     O      doub N N 73  
ALA   C     OXT    sing N N 74  
ALA   CB    HB1    sing N N 75  
ALA   CB    HB2    sing N N 76  
ALA   CB    HB3    sing N N 77  
ALA   OXT   HXT    sing N N 78  
ARG   N     CA     sing N N 79  
ARG   N     H      sing N N 80  
ARG   N     H2     sing N N 81  
ARG   CA    C      sing N N 82  
ARG   CA    CB     sing N N 83  
ARG   CA    HA     sing N N 84  
ARG   C     O      doub N N 85  
ARG   C     OXT    sing N N 86  
ARG   CB    CG     sing N N 87  
ARG   CB    HB2    sing N N 88  
ARG   CB    HB3    sing N N 89  
ARG   CG    CD     sing N N 90  
ARG   CG    HG2    sing N N 91  
ARG   CG    HG3    sing N N 92  
ARG   CD    NE     sing N N 93  
ARG   CD    HD2    sing N N 94  
ARG   CD    HD3    sing N N 95  
ARG   NE    CZ     sing N N 96  
ARG   NE    HE     sing N N 97  
ARG   CZ    NH1    sing N N 98  
ARG   CZ    NH2    doub N N 99  
ARG   NH1   HH11   sing N N 100 
ARG   NH1   HH12   sing N N 101 
ARG   NH2   HH21   sing N N 102 
ARG   NH2   HH22   sing N N 103 
ARG   OXT   HXT    sing N N 104 
ASN   N     CA     sing N N 105 
ASN   N     H      sing N N 106 
ASN   N     H2     sing N N 107 
ASN   CA    C      sing N N 108 
ASN   CA    CB     sing N N 109 
ASN   CA    HA     sing N N 110 
ASN   C     O      doub N N 111 
ASN   C     OXT    sing N N 112 
ASN   CB    CG     sing N N 113 
ASN   CB    HB2    sing N N 114 
ASN   CB    HB3    sing N N 115 
ASN   CG    OD1    doub N N 116 
ASN   CG    ND2    sing N N 117 
ASN   ND2   HD21   sing N N 118 
ASN   ND2   HD22   sing N N 119 
ASN   OXT   HXT    sing N N 120 
ASP   N     CA     sing N N 121 
ASP   N     H      sing N N 122 
ASP   N     H2     sing N N 123 
ASP   CA    C      sing N N 124 
ASP   CA    CB     sing N N 125 
ASP   CA    HA     sing N N 126 
ASP   C     O      doub N N 127 
ASP   C     OXT    sing N N 128 
ASP   CB    CG     sing N N 129 
ASP   CB    HB2    sing N N 130 
ASP   CB    HB3    sing N N 131 
ASP   CG    OD1    doub N N 132 
ASP   CG    OD2    sing N N 133 
ASP   OD2   HD2    sing N N 134 
ASP   OXT   HXT    sing N N 135 
C     OP3   P      sing N N 136 
C     OP3   HOP3   sing N N 137 
C     P     OP1    doub N N 138 
C     P     OP2    sing N N 139 
C     P     "O5'"  sing N N 140 
C     OP2   HOP2   sing N N 141 
C     "O5'" "C5'"  sing N N 142 
C     "C5'" "C4'"  sing N N 143 
C     "C5'" "H5'"  sing N N 144 
C     "C5'" "H5''" sing N N 145 
C     "C4'" "O4'"  sing N N 146 
C     "C4'" "C3'"  sing N N 147 
C     "C4'" "H4'"  sing N N 148 
C     "O4'" "C1'"  sing N N 149 
C     "C3'" "O3'"  sing N N 150 
C     "C3'" "C2'"  sing N N 151 
C     "C3'" "H3'"  sing N N 152 
C     "O3'" "HO3'" sing N N 153 
C     "C2'" "O2'"  sing N N 154 
C     "C2'" "C1'"  sing N N 155 
C     "C2'" "H2'"  sing N N 156 
C     "O2'" "HO2'" sing N N 157 
C     "C1'" N1     sing N N 158 
C     "C1'" "H1'"  sing N N 159 
C     N1    C2     sing N N 160 
C     N1    C6     sing N N 161 
C     C2    O2     doub N N 162 
C     C2    N3     sing N N 163 
C     N3    C4     doub N N 164 
C     C4    N4     sing N N 165 
C     C4    C5     sing N N 166 
C     N4    H41    sing N N 167 
C     N4    H42    sing N N 168 
C     C5    C6     doub N N 169 
C     C5    H5     sing N N 170 
C     C6    H6     sing N N 171 
CYS   N     CA     sing N N 172 
CYS   N     H      sing N N 173 
CYS   N     H2     sing N N 174 
CYS   CA    C      sing N N 175 
CYS   CA    CB     sing N N 176 
CYS   CA    HA     sing N N 177 
CYS   C     O      doub N N 178 
CYS   C     OXT    sing N N 179 
CYS   CB    SG     sing N N 180 
CYS   CB    HB2    sing N N 181 
CYS   CB    HB3    sing N N 182 
CYS   SG    HG     sing N N 183 
CYS   OXT   HXT    sing N N 184 
GLN   N     CA     sing N N 185 
GLN   N     H      sing N N 186 
GLN   N     H2     sing N N 187 
GLN   CA    C      sing N N 188 
GLN   CA    CB     sing N N 189 
GLN   CA    HA     sing N N 190 
GLN   C     O      doub N N 191 
GLN   C     OXT    sing N N 192 
GLN   CB    CG     sing N N 193 
GLN   CB    HB2    sing N N 194 
GLN   CB    HB3    sing N N 195 
GLN   CG    CD     sing N N 196 
GLN   CG    HG2    sing N N 197 
GLN   CG    HG3    sing N N 198 
GLN   CD    OE1    doub N N 199 
GLN   CD    NE2    sing N N 200 
GLN   NE2   HE21   sing N N 201 
GLN   NE2   HE22   sing N N 202 
GLN   OXT   HXT    sing N N 203 
GLU   N     CA     sing N N 204 
GLU   N     H      sing N N 205 
GLU   N     H2     sing N N 206 
GLU   CA    C      sing N N 207 
GLU   CA    CB     sing N N 208 
GLU   CA    HA     sing N N 209 
GLU   C     O      doub N N 210 
GLU   C     OXT    sing N N 211 
GLU   CB    CG     sing N N 212 
GLU   CB    HB2    sing N N 213 
GLU   CB    HB3    sing N N 214 
GLU   CG    CD     sing N N 215 
GLU   CG    HG2    sing N N 216 
GLU   CG    HG3    sing N N 217 
GLU   CD    OE1    doub N N 218 
GLU   CD    OE2    sing N N 219 
GLU   OE2   HE2    sing N N 220 
GLU   OXT   HXT    sing N N 221 
GLY   N     CA     sing N N 222 
GLY   N     H      sing N N 223 
GLY   N     H2     sing N N 224 
GLY   CA    C      sing N N 225 
GLY   CA    HA2    sing N N 226 
GLY   CA    HA3    sing N N 227 
GLY   C     O      doub N N 228 
GLY   C     OXT    sing N N 229 
GLY   OXT   HXT    sing N N 230 
HIS   N     CA     sing N N 231 
HIS   N     H      sing N N 232 
HIS   N     H2     sing N N 233 
HIS   CA    C      sing N N 234 
HIS   CA    CB     sing N N 235 
HIS   CA    HA     sing N N 236 
HIS   C     O      doub N N 237 
HIS   C     OXT    sing N N 238 
HIS   CB    CG     sing N N 239 
HIS   CB    HB2    sing N N 240 
HIS   CB    HB3    sing N N 241 
HIS   CG    ND1    sing Y N 242 
HIS   CG    CD2    doub Y N 243 
HIS   ND1   CE1    doub Y N 244 
HIS   ND1   HD1    sing N N 245 
HIS   CD2   NE2    sing Y N 246 
HIS   CD2   HD2    sing N N 247 
HIS   CE1   NE2    sing Y N 248 
HIS   CE1   HE1    sing N N 249 
HIS   NE2   HE2    sing N N 250 
HIS   OXT   HXT    sing N N 251 
ILE   N     CA     sing N N 252 
ILE   N     H      sing N N 253 
ILE   N     H2     sing N N 254 
ILE   CA    C      sing N N 255 
ILE   CA    CB     sing N N 256 
ILE   CA    HA     sing N N 257 
ILE   C     O      doub N N 258 
ILE   C     OXT    sing N N 259 
ILE   CB    CG1    sing N N 260 
ILE   CB    CG2    sing N N 261 
ILE   CB    HB     sing N N 262 
ILE   CG1   CD1    sing N N 263 
ILE   CG1   HG12   sing N N 264 
ILE   CG1   HG13   sing N N 265 
ILE   CG2   HG21   sing N N 266 
ILE   CG2   HG22   sing N N 267 
ILE   CG2   HG23   sing N N 268 
ILE   CD1   HD11   sing N N 269 
ILE   CD1   HD12   sing N N 270 
ILE   CD1   HD13   sing N N 271 
ILE   OXT   HXT    sing N N 272 
LEU   N     CA     sing N N 273 
LEU   N     H      sing N N 274 
LEU   N     H2     sing N N 275 
LEU   CA    C      sing N N 276 
LEU   CA    CB     sing N N 277 
LEU   CA    HA     sing N N 278 
LEU   C     O      doub N N 279 
LEU   C     OXT    sing N N 280 
LEU   CB    CG     sing N N 281 
LEU   CB    HB2    sing N N 282 
LEU   CB    HB3    sing N N 283 
LEU   CG    CD1    sing N N 284 
LEU   CG    CD2    sing N N 285 
LEU   CG    HG     sing N N 286 
LEU   CD1   HD11   sing N N 287 
LEU   CD1   HD12   sing N N 288 
LEU   CD1   HD13   sing N N 289 
LEU   CD2   HD21   sing N N 290 
LEU   CD2   HD22   sing N N 291 
LEU   CD2   HD23   sing N N 292 
LEU   OXT   HXT    sing N N 293 
LYS   N     CA     sing N N 294 
LYS   N     H      sing N N 295 
LYS   N     H2     sing N N 296 
LYS   CA    C      sing N N 297 
LYS   CA    CB     sing N N 298 
LYS   CA    HA     sing N N 299 
LYS   C     O      doub N N 300 
LYS   C     OXT    sing N N 301 
LYS   CB    CG     sing N N 302 
LYS   CB    HB2    sing N N 303 
LYS   CB    HB3    sing N N 304 
LYS   CG    CD     sing N N 305 
LYS   CG    HG2    sing N N 306 
LYS   CG    HG3    sing N N 307 
LYS   CD    CE     sing N N 308 
LYS   CD    HD2    sing N N 309 
LYS   CD    HD3    sing N N 310 
LYS   CE    NZ     sing N N 311 
LYS   CE    HE2    sing N N 312 
LYS   CE    HE3    sing N N 313 
LYS   NZ    HZ1    sing N N 314 
LYS   NZ    HZ2    sing N N 315 
LYS   NZ    HZ3    sing N N 316 
LYS   OXT   HXT    sing N N 317 
MET   N     CA     sing N N 318 
MET   N     H      sing N N 319 
MET   N     H2     sing N N 320 
MET   CA    C      sing N N 321 
MET   CA    CB     sing N N 322 
MET   CA    HA     sing N N 323 
MET   C     O      doub N N 324 
MET   C     OXT    sing N N 325 
MET   CB    CG     sing N N 326 
MET   CB    HB2    sing N N 327 
MET   CB    HB3    sing N N 328 
MET   CG    SD     sing N N 329 
MET   CG    HG2    sing N N 330 
MET   CG    HG3    sing N N 331 
MET   SD    CE     sing N N 332 
MET   CE    HE1    sing N N 333 
MET   CE    HE2    sing N N 334 
MET   CE    HE3    sing N N 335 
MET   OXT   HXT    sing N N 336 
PHE   N     CA     sing N N 337 
PHE   N     H      sing N N 338 
PHE   N     H2     sing N N 339 
PHE   CA    C      sing N N 340 
PHE   CA    CB     sing N N 341 
PHE   CA    HA     sing N N 342 
PHE   C     O      doub N N 343 
PHE   C     OXT    sing N N 344 
PHE   CB    CG     sing N N 345 
PHE   CB    HB2    sing N N 346 
PHE   CB    HB3    sing N N 347 
PHE   CG    CD1    doub Y N 348 
PHE   CG    CD2    sing Y N 349 
PHE   CD1   CE1    sing Y N 350 
PHE   CD1   HD1    sing N N 351 
PHE   CD2   CE2    doub Y N 352 
PHE   CD2   HD2    sing N N 353 
PHE   CE1   CZ     doub Y N 354 
PHE   CE1   HE1    sing N N 355 
PHE   CE2   CZ     sing Y N 356 
PHE   CE2   HE2    sing N N 357 
PHE   CZ    HZ     sing N N 358 
PHE   OXT   HXT    sing N N 359 
PRO   N     CA     sing N N 360 
PRO   N     CD     sing N N 361 
PRO   N     H      sing N N 362 
PRO   CA    C      sing N N 363 
PRO   CA    CB     sing N N 364 
PRO   CA    HA     sing N N 365 
PRO   C     O      doub N N 366 
PRO   C     OXT    sing N N 367 
PRO   CB    CG     sing N N 368 
PRO   CB    HB2    sing N N 369 
PRO   CB    HB3    sing N N 370 
PRO   CG    CD     sing N N 371 
PRO   CG    HG2    sing N N 372 
PRO   CG    HG3    sing N N 373 
PRO   CD    HD2    sing N N 374 
PRO   CD    HD3    sing N N 375 
PRO   OXT   HXT    sing N N 376 
SER   N     CA     sing N N 377 
SER   N     H      sing N N 378 
SER   N     H2     sing N N 379 
SER   CA    C      sing N N 380 
SER   CA    CB     sing N N 381 
SER   CA    HA     sing N N 382 
SER   C     O      doub N N 383 
SER   C     OXT    sing N N 384 
SER   CB    OG     sing N N 385 
SER   CB    HB2    sing N N 386 
SER   CB    HB3    sing N N 387 
SER   OG    HG     sing N N 388 
SER   OXT   HXT    sing N N 389 
THR   N     CA     sing N N 390 
THR   N     H      sing N N 391 
THR   N     H2     sing N N 392 
THR   CA    C      sing N N 393 
THR   CA    CB     sing N N 394 
THR   CA    HA     sing N N 395 
THR   C     O      doub N N 396 
THR   C     OXT    sing N N 397 
THR   CB    OG1    sing N N 398 
THR   CB    CG2    sing N N 399 
THR   CB    HB     sing N N 400 
THR   OG1   HG1    sing N N 401 
THR   CG2   HG21   sing N N 402 
THR   CG2   HG22   sing N N 403 
THR   CG2   HG23   sing N N 404 
THR   OXT   HXT    sing N N 405 
TRP   N     CA     sing N N 406 
TRP   N     H      sing N N 407 
TRP   N     H2     sing N N 408 
TRP   CA    C      sing N N 409 
TRP   CA    CB     sing N N 410 
TRP   CA    HA     sing N N 411 
TRP   C     O      doub N N 412 
TRP   C     OXT    sing N N 413 
TRP   CB    CG     sing N N 414 
TRP   CB    HB2    sing N N 415 
TRP   CB    HB3    sing N N 416 
TRP   CG    CD1    doub Y N 417 
TRP   CG    CD2    sing Y N 418 
TRP   CD1   NE1    sing Y N 419 
TRP   CD1   HD1    sing N N 420 
TRP   CD2   CE2    doub Y N 421 
TRP   CD2   CE3    sing Y N 422 
TRP   NE1   CE2    sing Y N 423 
TRP   NE1   HE1    sing N N 424 
TRP   CE2   CZ2    sing Y N 425 
TRP   CE3   CZ3    doub Y N 426 
TRP   CE3   HE3    sing N N 427 
TRP   CZ2   CH2    doub Y N 428 
TRP   CZ2   HZ2    sing N N 429 
TRP   CZ3   CH2    sing Y N 430 
TRP   CZ3   HZ3    sing N N 431 
TRP   CH2   HH2    sing N N 432 
TRP   OXT   HXT    sing N N 433 
TYR   N     CA     sing N N 434 
TYR   N     H      sing N N 435 
TYR   N     H2     sing N N 436 
TYR   CA    C      sing N N 437 
TYR   CA    CB     sing N N 438 
TYR   CA    HA     sing N N 439 
TYR   C     O      doub N N 440 
TYR   C     OXT    sing N N 441 
TYR   CB    CG     sing N N 442 
TYR   CB    HB2    sing N N 443 
TYR   CB    HB3    sing N N 444 
TYR   CG    CD1    doub Y N 445 
TYR   CG    CD2    sing Y N 446 
TYR   CD1   CE1    sing Y N 447 
TYR   CD1   HD1    sing N N 448 
TYR   CD2   CE2    doub Y N 449 
TYR   CD2   HD2    sing N N 450 
TYR   CE1   CZ     doub Y N 451 
TYR   CE1   HE1    sing N N 452 
TYR   CE2   CZ     sing Y N 453 
TYR   CE2   HE2    sing N N 454 
TYR   CZ    OH     sing N N 455 
TYR   OH    HH     sing N N 456 
TYR   OXT   HXT    sing N N 457 
U     OP3   P      sing N N 458 
U     OP3   HOP3   sing N N 459 
U     P     OP1    doub N N 460 
U     P     OP2    sing N N 461 
U     P     "O5'"  sing N N 462 
U     OP2   HOP2   sing N N 463 
U     "O5'" "C5'"  sing N N 464 
U     "C5'" "C4'"  sing N N 465 
U     "C5'" "H5'"  sing N N 466 
U     "C5'" "H5''" sing N N 467 
U     "C4'" "O4'"  sing N N 468 
U     "C4'" "C3'"  sing N N 469 
U     "C4'" "H4'"  sing N N 470 
U     "O4'" "C1'"  sing N N 471 
U     "C3'" "O3'"  sing N N 472 
U     "C3'" "C2'"  sing N N 473 
U     "C3'" "H3'"  sing N N 474 
U     "O3'" "HO3'" sing N N 475 
U     "C2'" "O2'"  sing N N 476 
U     "C2'" "C1'"  sing N N 477 
U     "C2'" "H2'"  sing N N 478 
U     "O2'" "HO2'" sing N N 479 
U     "C1'" N1     sing N N 480 
U     "C1'" "H1'"  sing N N 481 
U     N1    C2     sing N N 482 
U     N1    C6     sing N N 483 
U     C2    O2     doub N N 484 
U     C2    N3     sing N N 485 
U     N3    C4     sing N N 486 
U     N3    H3     sing N N 487 
U     C4    O4     doub N N 488 
U     C4    C5     sing N N 489 
U     C5    C6     doub N N 490 
U     C5    H5     sing N N 491 
U     C6    H6     sing N N 492 
VAL   N     CA     sing N N 493 
VAL   N     H      sing N N 494 
VAL   N     H2     sing N N 495 
VAL   CA    C      sing N N 496 
VAL   CA    CB     sing N N 497 
VAL   CA    HA     sing N N 498 
VAL   C     O      doub N N 499 
VAL   C     OXT    sing N N 500 
VAL   CB    CG1    sing N N 501 
VAL   CB    CG2    sing N N 502 
VAL   CB    HB     sing N N 503 
VAL   CG1   HG11   sing N N 504 
VAL   CG1   HG12   sing N N 505 
VAL   CG1   HG13   sing N N 506 
VAL   CG2   HG21   sing N N 507 
VAL   CG2   HG22   sing N N 508 
VAL   CG2   HG23   sing N N 509 
VAL   OXT   HXT    sing N N 510 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-29 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9GAV 
_em_admin.last_update        2025-02-12 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              
'Focused reconstruction on strand 1 of the influenza A RNP-like particle double-stranded assembled with a 18-mer RNA.' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 20  mM ?    1 HEPES                   
1 150 mM NaCl 2 NaCl                    
1 5   mM ?    3 beta-mercaptoethanol    
1 2   mM ?    4 methyl-PEG8-NHS         
1 4   uM ?    5 
;RNA (5'P-(UC)6-FAM3')
;
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 2 2 11320 'Influenza A virus'   ? ? ? ? ? 
? ? 3 3 32630 'synthetic construct' ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 2 2 469008 'Escherichia coli BL21(DE3)' ? ? 
? 3 3 32630  'synthetic construct'        ? ? 
# 
_em_helical_entity.id                             1 
_em_helical_entity.image_processing_id            1 
_em_helical_entity.details                        ? 
_em_helical_entity.axial_symmetry                 C1 
_em_helical_entity.angular_rotation_per_subunit   56.13 
_em_helical_entity.axial_rise_per_subunit         27.3 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         53 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?         ?            
'MODEL REFINEMENT'              ? 2  ? ? ? PHENIX    1.20.1_4487: 
'IMAGE ACQUISITION'             ? 3  ? ? 1 SerialEM  ?            
MASKING                         ? 4  ? ? ? ?         ?            
'CTF CORRECTION'                ? 5  1 ? ? ?         ?            
'LAYERLINE INDEXING'            ? 6  ? ? ? ?         ?            
'DIFFRACTION INDEXING'          ? 7  ? ? ? ?         ?            
'MODEL FITTING'                 ? 8  ? ? ? ?         ?            
OTHER                           ? 9  ? ? ? ?         ?            
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?         ?            
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?         ?            
CLASSIFICATION                  ? 12 1 ? ? ?         ?            
RECONSTRUCTION                  ? 13 1 ? ? cryoSPARC ?            
'VOLUME SELECTION'              ? 14 1 1 1 ?         ?            
'SERIES ALIGNMENT'              ? 15 1 1 1 ?         ?            
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?         ?            
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?         ?            
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?         ?            
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?         ?            
# 
_em_specimen.concentration           0.23 
_em_specimen.details                 
;20 mM HEPES
150 mM NaCl
5 mM betamercaptoethanol
Incubation overnight with 0.004 uM RNA.
Prior freezing, the sample was incubated with 2 mM methyl PEG8 N hydroxysuccinimide ester reagent.
;
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Agence Nationale de la Recherche (ANR)'                          France ANR-23-CE11-01      1 
'Grenoble Alliance for Integrated Structural Cell Biology (GRAL)' France ANR-17-EURE-0003    2 
'Grenoble Instruct-ERIC Center (ISBG)'                            France ANR-10-INSB-0005-02 3 
# 
_atom_sites.entry_id                    9GAV 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N      . GLY   A 1 392 ? 257.251 238.863 179.060 1.00 31.34  ? 404 GLY   G N      1 
ATOM   2    C CA     . GLY   A 1 392 ? 258.048 239.786 179.846 1.00 42.35  ? 404 GLY   G CA     1 
ATOM   3    C C      . GLY   A 1 392 ? 257.300 240.366 181.029 1.00 49.10  ? 404 GLY   G C      1 
ATOM   4    O O      . GLY   A 1 392 ? 256.203 239.921 181.356 1.00 59.09  ? 404 GLY   G O      1 
ATOM   5    N N      . GLN   A 1 393 ? 257.898 241.363 181.674 1.00 43.47  ? 405 GLN   G N      1 
ATOM   6    C CA     . GLN   A 1 393 ? 257.282 242.023 182.815 1.00 44.84  ? 405 GLN   G CA     1 
ATOM   7    C C      . GLN   A 1 393 ? 256.336 243.115 182.337 1.00 47.57  ? 405 GLN   G C      1 
ATOM   8    O O      . GLN   A 1 393 ? 256.667 243.894 181.440 1.00 47.81  ? 405 GLN   G O      1 
ATOM   9    C CB     . GLN   A 1 393 ? 258.349 242.619 183.734 1.00 45.27  ? 405 GLN   G CB     1 
ATOM   10   C CG     . GLN   A 1 393 ? 257.817 243.143 185.053 1.00 41.33  ? 405 GLN   G CG     1 
ATOM   11   C CD     . GLN   A 1 393 ? 258.922 243.544 186.006 1.00 43.02  ? 405 GLN   G CD     1 
ATOM   12   O OE1    . GLN   A 1 393 ? 260.096 243.274 185.761 1.00 53.61  ? 405 GLN   G OE1    1 
ATOM   13   N NE2    . GLN   A 1 393 ? 258.552 244.198 187.098 1.00 37.29  ? 405 GLN   G NE2    1 
ATOM   14   N N      . ILE   A 1 394 ? 255.152 243.166 182.942 1.00 47.71  ? 406 ILE   G N      1 
ATOM   15   C CA     . ILE   A 1 394 ? 254.122 244.104 182.511 1.00 47.85  ? 406 ILE   G CA     1 
ATOM   16   C C      . ILE   A 1 394 ? 253.557 244.858 183.707 1.00 47.65  ? 406 ILE   G C      1 
ATOM   17   O O      . ILE   A 1 394 ? 252.535 245.542 183.593 1.00 51.42  ? 406 ILE   G O      1 
ATOM   18   C CB     . ILE   A 1 394 ? 253.003 243.375 181.744 1.00 50.33  ? 406 ILE   G CB     1 
ATOM   19   C CG1    . ILE   A 1 394 ? 251.989 242.778 182.716 1.00 45.04  ? 406 ILE   G CG1    1 
ATOM   20   C CG2    . ILE   A 1 394 ? 253.584 242.291 180.854 1.00 55.86  ? 406 ILE   G CG2    1 
ATOM   21   C CD1    . ILE   A 1 394 ? 250.850 242.060 182.032 1.00 47.05  ? 406 ILE   G CD1    1 
ATOM   22   N N      . SER   A 1 395 ? 254.215 244.749 184.855 1.00 45.35  ? 407 SER   G N      1 
ATOM   23   C CA     . SER   A 1 395 ? 253.726 245.394 186.064 1.00 45.32  ? 407 SER   G CA     1 
ATOM   24   C C      . SER   A 1 395 ? 254.913 245.752 186.948 1.00 45.97  ? 407 SER   G C      1 
ATOM   25   O O      . SER   A 1 395 ? 256.071 245.681 186.529 1.00 47.51  ? 407 SER   G O      1 
ATOM   26   C CB     . SER   A 1 395 ? 252.726 244.494 186.797 1.00 47.89  ? 407 SER   G CB     1 
ATOM   27   O OG     . SER   A 1 395 ? 251.984 245.237 187.746 1.00 50.60  ? 407 SER   G OG     1 
ATOM   28   N N      . ILE   A 1 396 ? 254.613 246.139 188.186 1.00 45.90  ? 408 ILE   G N      1 
ATOM   29   C CA     . ILE   A 1 396 ? 255.619 246.553 189.151 1.00 44.49  ? 408 ILE   G CA     1 
ATOM   30   C C      . ILE   A 1 396 ? 255.123 246.205 190.546 1.00 47.58  ? 408 ILE   G C      1 
ATOM   31   O O      . ILE   A 1 396 ? 253.921 246.146 190.809 1.00 52.80  ? 408 ILE   G O      1 
ATOM   32   C CB     . ILE   A 1 396 ? 255.924 248.061 189.055 1.00 44.65  ? 408 ILE   G CB     1 
ATOM   33   C CG1    . ILE   A 1 396 ? 257.370 248.343 189.439 1.00 41.38  ? 408 ILE   G CG1    1 
ATOM   34   C CG2    . ILE   A 1 396 ? 254.985 248.851 189.951 1.00 49.09  ? 408 ILE   G CG2    1 
ATOM   35   C CD1    . ILE   A 1 396 ? 257.693 249.803 189.443 1.00 42.72  ? 408 ILE   G CD1    1 
ATOM   36   N N      . GLN   A 1 397 ? 256.073 245.971 191.447 1.00 42.42  ? 409 GLN   G N      1 
ATOM   37   C CA     . GLN   A 1 397 ? 255.770 245.731 192.852 1.00 43.89  ? 409 GLN   G CA     1 
ATOM   38   C C      . GLN   A 1 397 ? 256.695 246.620 193.669 1.00 46.87  ? 409 GLN   G C      1 
ATOM   39   O O      . GLN   A 1 397 ? 257.901 246.317 193.783 1.00 47.93  ? 409 GLN   G O      1 
ATOM   40   C CB     . GLN   A 1 397 ? 255.942 244.258 193.227 1.00 42.91  ? 409 GLN   G CB     1 
ATOM   41   C CG     . GLN   A 1 397 ? 255.612 243.961 194.678 1.00 42.88  ? 409 GLN   G CG     1 
ATOM   42   C CD     . GLN   A 1 397 ? 254.121 243.966 194.950 1.00 39.43  ? 409 GLN   G CD     1 
ATOM   43   O OE1    . GLN   A 1 397 ? 253.315 243.724 194.056 1.00 39.11  ? 409 GLN   G OE1    1 
ATOM   44   N NE2    . GLN   A 1 397 ? 253.748 244.254 196.190 1.00 42.08  ? 409 GLN   G NE2    1 
ATOM   45   N N      . PRO   A 1 398 ? 256.198 247.712 194.244 1.00 45.70  ? 410 PRO   G N      1 
ATOM   46   C CA     . PRO   A 1 398 ? 257.086 248.633 194.958 1.00 47.81  ? 410 PRO   G CA     1 
ATOM   47   C C      . PRO   A 1 398 ? 257.751 247.958 196.145 1.00 51.01  ? 410 PRO   G C      1 
ATOM   48   O O      . PRO   A 1 398 ? 257.153 247.123 196.826 1.00 53.40  ? 410 PRO   G O      1 
ATOM   49   C CB     . PRO   A 1 398 ? 256.144 249.757 195.407 1.00 47.80  ? 410 PRO   G CB     1 
ATOM   50   C CG     . PRO   A 1 398 ? 254.794 249.140 195.406 1.00 46.17  ? 410 PRO   G CG     1 
ATOM   51   C CD     . PRO   A 1 398 ? 254.797 248.156 194.283 1.00 45.70  ? 410 PRO   G CD     1 
ATOM   52   N N      . THR   A 1 399 ? 259.000 248.327 196.387 1.00 49.60  ? 411 THR   G N      1 
ATOM   53   C CA     . THR   A 1 399 ? 259.715 247.908 197.584 1.00 48.74  ? 411 THR   G CA     1 
ATOM   54   C C      . THR   A 1 399 ? 260.036 249.070 198.506 1.00 50.83  ? 411 THR   G C      1 
ATOM   55   O O      . THR   A 1 399 ? 260.013 248.908 199.727 1.00 53.32  ? 411 THR   G O      1 
ATOM   56   C CB     . THR   A 1 399 ? 261.016 247.184 197.206 1.00 47.90  ? 411 THR   G CB     1 
ATOM   57   O OG1    . THR   A 1 399 ? 261.829 247.018 198.373 1.00 51.34  ? 411 THR   G OG1    1 
ATOM   58   C CG2    . THR   A 1 399 ? 261.788 247.988 196.182 1.00 49.12  ? 411 THR   G CG2    1 
ATOM   59   N N      . PHE   A 1 400 ? 260.326 250.241 197.950 1.00 48.83  ? 412 PHE   G N      1 
ATOM   60   C CA     . PHE   A 1 400 ? 260.674 251.427 198.714 1.00 48.15  ? 412 PHE   G CA     1 
ATOM   61   C C      . PHE   A 1 400 ? 259.475 252.359 198.829 1.00 50.57  ? 412 PHE   G C      1 
ATOM   62   O O      . PHE   A 1 400 ? 258.604 252.390 197.956 1.00 54.50  ? 412 PHE   G O      1 
ATOM   63   C CB     . PHE   A 1 400 ? 261.842 252.166 198.058 1.00 46.00  ? 412 PHE   G CB     1 
ATOM   64   C CG     . PHE   A 1 400 ? 263.078 251.330 197.903 1.00 46.01  ? 412 PHE   G CG     1 
ATOM   65   C CD1    . PHE   A 1 400 ? 263.848 250.993 199.001 1.00 45.16  ? 412 PHE   G CD1    1 
ATOM   66   C CD2    . PHE   A 1 400 ? 263.471 250.882 196.655 1.00 44.55  ? 412 PHE   G CD2    1 
ATOM   67   C CE1    . PHE   A 1 400 ? 264.986 250.223 198.858 1.00 42.79  ? 412 PHE   G CE1    1 
ATOM   68   C CE2    . PHE   A 1 400 ? 264.606 250.112 196.505 1.00 42.59  ? 412 PHE   G CE2    1 
ATOM   69   C CZ     . PHE   A 1 400 ? 265.364 249.783 197.607 1.00 42.83  ? 412 PHE   G CZ     1 
ATOM   70   N N      . SER   A 1 401 ? 259.435 253.120 199.921 1.00 47.85  ? 413 SER   G N      1 
ATOM   71   C CA     . SER   A 1 401 ? 258.399 254.132 200.129 1.00 48.26  ? 413 SER   G CA     1 
ATOM   72   C C      . SER   A 1 401 ? 258.855 255.436 199.488 1.00 53.93  ? 413 SER   G C      1 
ATOM   73   O O      . SER   A 1 401 ? 259.543 256.252 200.102 1.00 60.54  ? 413 SER   G O      1 
ATOM   74   C CB     . SER   A 1 401 ? 258.108 254.319 201.613 1.00 44.69  ? 413 SER   G CB     1 
ATOM   75   O OG     . SER   A 1 401 ? 257.253 253.306 202.106 1.00 41.82  ? 413 SER   G OG     1 
ATOM   76   N N      . VAL   A 1 402 ? 258.466 255.634 198.232 1.00 50.67  ? 414 VAL   G N      1 
ATOM   77   C CA     . VAL   A 1 402 ? 258.749 256.861 197.502 1.00 49.17  ? 414 VAL   G CA     1 
ATOM   78   C C      . VAL   A 1 402 ? 257.488 257.287 196.764 1.00 51.23  ? 414 VAL   G C      1 
ATOM   79   O O      . VAL   A 1 402 ? 256.579 256.484 196.537 1.00 57.07  ? 414 VAL   G O      1 
ATOM   80   C CB     . VAL   A 1 402 ? 259.930 256.692 196.522 1.00 51.45  ? 414 VAL   G CB     1 
ATOM   81   C CG1    . VAL   A 1 402 ? 260.433 258.045 196.062 1.00 50.55  ? 414 VAL   G CG1    1 
ATOM   82   C CG2    . VAL   A 1 402 ? 261.049 255.906 197.178 1.00 48.15  ? 414 VAL   G CG2    1 
ATOM   83   N N      . GLN   A 1 403 ? 257.441 258.562 196.382 1.00 52.16  ? 415 GLN   G N      1 
ATOM   84   C CA     . GLN   A 1 403 ? 256.267 259.170 195.752 1.00 55.29  ? 415 GLN   G CA     1 
ATOM   85   C C      . GLN   A 1 403 ? 256.087 258.768 194.281 1.00 55.18  ? 415 GLN   G C      1 
ATOM   86   O O      . GLN   A 1 403 ? 255.230 259.330 193.591 1.00 62.68  ? 415 GLN   G O      1 
ATOM   87   C CB     . GLN   A 1 403 ? 256.353 260.693 195.876 1.00 53.25  ? 415 GLN   G CB     1 
ATOM   88   C CG     . GLN   A 1 403 ? 255.239 261.455 195.176 1.00 49.66  ? 415 GLN   G CG     1 
ATOM   89   C CD     . GLN   A 1 403 ? 255.100 262.876 195.667 1.00 53.04  ? 415 GLN   G CD     1 
ATOM   90   O OE1    . GLN   A 1 403 ? 255.777 263.289 196.606 1.00 59.06  ? 415 GLN   G OE1    1 
ATOM   91   N NE2    . GLN   A 1 403 ? 254.221 263.636 195.030 1.00 53.42  ? 415 GLN   G NE2    1 
ATOM   92   N N      . ARG   A 1 404 ? 256.836 257.802 193.759 1.00 52.50  ? 416 ARG   G N      1 
ATOM   93   C CA     . ARG   A 1 404 ? 256.728 257.443 192.354 1.00 50.76  ? 416 ARG   G CA     1 
ATOM   94   C C      . ARG   A 1 404 ? 255.307 256.979 192.030 1.00 52.23  ? 416 ARG   G C      1 
ATOM   95   O O      . ARG   A 1 404 ? 254.463 256.791 192.911 1.00 54.13  ? 416 ARG   G O      1 
ATOM   96   C CB     . ARG   A 1 404 ? 257.750 256.361 192.009 1.00 52.98  ? 416 ARG   G CB     1 
ATOM   97   C CG     . ARG   A 1 404 ? 257.175 254.956 191.873 1.00 53.37  ? 416 ARG   G CG     1 
ATOM   98   C CD     . ARG   A 1 404 ? 256.604 254.414 193.175 1.00 50.81  ? 416 ARG   G CD     1 
ATOM   99   N NE     . ARG   A 1 404 ? 257.607 254.281 194.223 1.00 47.41  ? 416 ARG   G NE     1 
ATOM   100  C CZ     . ARG   A 1 404 ? 258.214 253.144 194.531 1.00 48.68  ? 416 ARG   G CZ     1 
ATOM   101  N NH1    . ARG   A 1 404 ? 257.971 252.028 193.865 1.00 45.90  ? 416 ARG   G NH1    1 
ATOM   102  N NH2    . ARG   A 1 404 ? 259.093 253.127 195.529 1.00 53.25  ? 416 ARG   G NH2    1 
ATOM   103  N N      . ASN   A 1 405 ? 255.038 256.801 190.741 1.00 53.35  ? 417 ASN   G N      1 
ATOM   104  C CA     . ASN   A 1 405 ? 253.796 256.210 190.264 1.00 50.76  ? 417 ASN   G CA     1 
ATOM   105  C C      . ASN   A 1 405 ? 254.075 254.778 189.832 1.00 52.79  ? 417 ASN   G C      1 
ATOM   106  O O      . ASN   A 1 405 ? 255.029 254.527 189.088 1.00 56.62  ? 417 ASN   G O      1 
ATOM   107  C CB     . ASN   A 1 405 ? 253.215 257.002 189.094 1.00 51.03  ? 417 ASN   G CB     1 
ATOM   108  C CG     . ASN   A 1 405 ? 254.220 257.220 187.985 1.00 52.35  ? 417 ASN   G CG     1 
ATOM   109  O OD1    . ASN   A 1 405 ? 255.178 257.976 188.139 1.00 57.19  ? 417 ASN   G OD1    1 
ATOM   110  N ND2    . ASN   A 1 405 ? 254.012 256.550 186.859 1.00 44.42  ? 417 ASN   G ND2    1 
ATOM   111  N N      . LEU   A 1 406 ? 253.252 253.847 190.294 1.00 48.14  ? 418 LEU   G N      1 
ATOM   112  C CA     . LEU   A 1 406 ? 253.470 252.443 189.974 1.00 49.96  ? 418 LEU   G CA     1 
ATOM   113  C C      . LEU   A 1 406 ? 252.991 252.145 188.559 1.00 48.99  ? 418 LEU   G C      1 
ATOM   114  O O      . LEU   A 1 406 ? 251.781 252.068 188.314 1.00 50.12  ? 418 LEU   G O      1 
ATOM   115  C CB     . LEU   A 1 406 ? 252.758 251.547 190.988 1.00 52.13  ? 418 LEU   G CB     1 
ATOM   116  C CG     . LEU   A 1 406 ? 252.754 252.050 192.432 1.00 51.73  ? 418 LEU   G CG     1 
ATOM   117  C CD1    . LEU   A 1 406 ? 251.839 251.197 193.292 1.00 59.29  ? 418 LEU   G CD1    1 
ATOM   118  C CD2    . LEU   A 1 406 ? 254.160 252.059 192.997 1.00 46.69  ? 418 LEU   G CD2    1 
ATOM   119  N N      . PRO   A 1 407 ? 253.899 251.973 187.606 1.00 47.71  ? 419 PRO   G N      1 
ATOM   120  C CA     . PRO   A 1 407 ? 253.486 251.736 186.222 1.00 44.22  ? 419 PRO   G CA     1 
ATOM   121  C C      . PRO   A 1 407 ? 252.995 250.312 186.007 1.00 46.45  ? 419 PRO   G C      1 
ATOM   122  O O      . PRO   A 1 407 ? 253.335 249.382 186.740 1.00 48.72  ? 419 PRO   G O      1 
ATOM   123  C CB     . PRO   A 1 407 ? 254.764 252.000 185.412 1.00 41.13  ? 419 PRO   G CB     1 
ATOM   124  C CG     . PRO   A 1 407 ? 255.809 252.443 186.404 1.00 43.77  ? 419 PRO   G CG     1 
ATOM   125  C CD     . PRO   A 1 407 ? 255.362 251.982 187.746 1.00 48.32  ? 419 PRO   G CD     1 
ATOM   126  N N      . PHE   A 1 408 ? 252.168 250.162 184.977 1.00 44.83  ? 420 PHE   G N      1 
ATOM   127  C CA     . PHE   A 1 408 ? 251.766 248.849 184.499 1.00 43.24  ? 420 PHE   G CA     1 
ATOM   128  C C      . PHE   A 1 408 ? 251.382 248.976 183.035 1.00 44.13  ? 420 PHE   G C      1 
ATOM   129  O O      . PHE   A 1 408 ? 251.019 250.058 182.568 1.00 48.15  ? 420 PHE   G O      1 
ATOM   130  C CB     . PHE   A 1 408 ? 250.597 248.267 185.302 1.00 43.05  ? 420 PHE   G CB     1 
ATOM   131  C CG     . PHE   A 1 408 ? 249.479 249.236 185.546 1.00 42.06  ? 420 PHE   G CG     1 
ATOM   132  C CD1    . PHE   A 1 408 ? 249.502 250.087 186.636 1.00 41.87  ? 420 PHE   G CD1    1 
ATOM   133  C CD2    . PHE   A 1 408 ? 248.398 249.291 184.686 1.00 44.22  ? 420 PHE   G CD2    1 
ATOM   134  C CE1    . PHE   A 1 408 ? 248.471 250.973 186.860 1.00 43.06  ? 420 PHE   G CE1    1 
ATOM   135  C CE2    . PHE   A 1 408 ? 247.364 250.174 184.907 1.00 45.29  ? 420 PHE   G CE2    1 
ATOM   136  C CZ     . PHE   A 1 408 ? 247.401 251.016 185.994 1.00 43.76  ? 420 PHE   G CZ     1 
ATOM   137  N N      . ASP   A 1 409 ? 251.468 247.859 182.315 1.00 42.81  ? 421 ASP   G N      1 
ATOM   138  C CA     . ASP   A 1 409 ? 251.071 247.821 180.909 1.00 47.01  ? 421 ASP   G CA     1 
ATOM   139  C C      . ASP   A 1 409 ? 249.562 247.608 180.854 1.00 47.05  ? 421 ASP   G C      1 
ATOM   140  O O      . ASP   A 1 409 ? 249.054 246.489 180.756 1.00 49.73  ? 421 ASP   G O      1 
ATOM   141  C CB     . ASP   A 1 409 ? 251.828 246.733 180.160 1.00 49.76  ? 421 ASP   G CB     1 
ATOM   142  C CG     . ASP   A 1 409 ? 251.912 247.002 178.674 1.00 51.91  ? 421 ASP   G CG     1 
ATOM   143  O OD1    . ASP   A 1 409 ? 253.030 247.251 178.177 1.00 58.10  ? 421 ASP   G OD1    1 
ATOM   144  O OD2    . ASP   A 1 409 ? 250.861 246.975 178.003 1.00 52.56  ? 421 ASP   G OD2    1 
ATOM   145  N N      . ARG   A 1 410 ? 248.834 248.718 180.927 1.00 45.52  ? 422 ARG   G N      1 
ATOM   146  C CA     . ARG   A 1 410 ? 247.375 248.660 180.976 1.00 48.40  ? 422 ARG   G CA     1 
ATOM   147  C C      . ARG   A 1 410 ? 246.756 247.928 179.794 1.00 48.86  ? 422 ARG   G C      1 
ATOM   148  O O      . ARG   A 1 410 ? 245.940 247.020 180.018 1.00 47.93  ? 422 ARG   G O      1 
ATOM   149  C CB     . ARG   A 1 410 ? 246.820 250.086 181.073 1.00 48.22  ? 422 ARG   G CB     1 
ATOM   150  C CG     . ARG   A 1 410 ? 245.325 250.161 180.886 1.00 49.85  ? 422 ARG   G CG     1 
ATOM   151  C CD     . ARG   A 1 410 ? 244.704 251.247 181.734 1.00 49.59  ? 422 ARG   G CD     1 
ATOM   152  N NE     . ARG   A 1 410 ? 243.284 250.996 181.936 1.00 59.61  ? 422 ARG   G NE     1 
ATOM   153  C CZ     . ARG   A 1 410 ? 242.365 251.120 180.989 1.00 64.44  ? 422 ARG   G CZ     1 
ATOM   154  N NH1    . ARG   A 1 410 ? 242.687 251.478 179.758 1.00 59.91  ? 422 ARG   G NH1    1 
ATOM   155  N NH2    . ARG   A 1 410 ? 241.092 250.873 181.284 1.00 66.93  ? 422 ARG   G NH2    1 
ATOM   156  N N      . PRO   A 1 411 ? 247.081 248.253 178.541 1.00 51.08  ? 423 PRO   G N      1 
ATOM   157  C CA     . PRO   A 1 411 ? 246.423 247.559 177.422 1.00 49.09  ? 423 PRO   G CA     1 
ATOM   158  C C      . PRO   A 1 411 ? 246.623 246.053 177.431 1.00 48.05  ? 423 PRO   G C      1 
ATOM   159  O O      . PRO   A 1 411 ? 245.718 245.312 177.031 1.00 49.09  ? 423 PRO   G O      1 
ATOM   160  C CB     . PRO   A 1 411 ? 247.061 248.213 176.190 1.00 45.67  ? 423 PRO   G CB     1 
ATOM   161  C CG     . PRO   A 1 411 ? 247.483 249.561 176.659 1.00 41.88  ? 423 PRO   G CG     1 
ATOM   162  C CD     . PRO   A 1 411 ? 247.906 249.385 178.086 1.00 46.59  ? 423 PRO   G CD     1 
ATOM   163  N N      . THR   A 1 412 ? 247.789 245.575 177.867 1.00 45.66  ? 424 THR   G N      1 
ATOM   164  C CA     . THR   A 1 412 ? 248.052 244.139 177.845 1.00 47.73  ? 424 THR   G CA     1 
ATOM   165  C C      . THR   A 1 412 ? 247.337 243.412 178.977 1.00 48.35  ? 424 THR   G C      1 
ATOM   166  O O      . THR   A 1 412 ? 246.884 242.276 178.799 1.00 47.90  ? 424 THR   G O      1 
ATOM   167  C CB     . THR   A 1 412 ? 249.555 243.880 177.917 1.00 49.84  ? 424 THR   G CB     1 
ATOM   168  O OG1    . THR   A 1 412 ? 250.179 244.348 176.716 1.00 49.47  ? 424 THR   G OG1    1 
ATOM   169  C CG2    . THR   A 1 412 ? 249.826 242.397 178.075 1.00 49.97  ? 424 THR   G CG2    1 
ATOM   170  N N      . ILE   A 1 413 ? 247.239 244.041 180.148 1.00 49.54  ? 425 ILE   G N      1 
ATOM   171  C CA     . ILE   A 1 413 ? 246.579 243.399 181.280 1.00 50.30  ? 425 ILE   G CA     1 
ATOM   172  C C      . ILE   A 1 413 ? 245.088 243.240 181.012 1.00 49.68  ? 425 ILE   G C      1 
ATOM   173  O O      . ILE   A 1 413 ? 244.496 242.199 181.319 1.00 47.51  ? 425 ILE   G O      1 
ATOM   174  C CB     . ILE   A 1 413 ? 246.847 244.196 182.568 1.00 49.85  ? 425 ILE   G CB     1 
ATOM   175  C CG1    . ILE   A 1 413 ? 248.338 244.174 182.895 1.00 44.92  ? 425 ILE   G CG1    1 
ATOM   176  C CG2    . ILE   A 1 413 ? 246.042 243.628 183.721 1.00 54.44  ? 425 ILE   G CG2    1 
ATOM   177  C CD1    . ILE   A 1 413 ? 248.689 244.864 184.184 1.00 47.62  ? 425 ILE   G CD1    1 
ATOM   178  N N      . MET   A 1 414 ? 244.458 244.264 180.438 1.00 51.66  ? 426 MET   G N      1 
ATOM   179  C CA     . MET   A 1 414 ? 243.032 244.215 180.146 1.00 53.07  ? 426 MET   G CA     1 
ATOM   180  C C      . MET   A 1 414 ? 242.714 243.488 178.849 1.00 54.94  ? 426 MET   G C      1 
ATOM   181  O O      . MET   A 1 414 ? 241.544 243.172 178.609 1.00 56.12  ? 426 MET   G O      1 
ATOM   182  C CB     . MET   A 1 414 ? 242.459 245.630 180.083 1.00 49.86  ? 426 MET   G CB     1 
ATOM   183  C CG     . MET   A 1 414 ? 242.903 246.523 181.217 1.00 50.75  ? 426 MET   G CG     1 
ATOM   184  S SD     . MET   A 1 414 ? 242.004 246.166 182.732 1.00 60.82  ? 426 MET   G SD     1 
ATOM   185  C CE     . MET   A 1 414 ? 242.023 247.777 183.502 1.00 66.13  ? 426 MET   G CE     1 
ATOM   186  N N      . ALA   A 1 415 ? 243.715 243.213 178.015 1.00 56.11  ? 427 ALA   G N      1 
ATOM   187  C CA     . ALA   A 1 415 ? 243.458 242.493 176.775 1.00 57.99  ? 427 ALA   G CA     1 
ATOM   188  C C      . ALA   A 1 415 ? 242.923 241.095 177.053 1.00 58.11  ? 427 ALA   G C      1 
ATOM   189  O O      . ALA   A 1 415 ? 242.010 240.623 176.366 1.00 61.99  ? 427 ALA   G O      1 
ATOM   190  C CB     . ALA   A 1 415 ? 244.730 242.425 175.931 1.00 58.48  ? 427 ALA   G CB     1 
ATOM   191  N N      . ALA   A 1 416 ? 243.473 240.420 178.057 1.00 53.27  ? 428 ALA   G N      1 
ATOM   192  C CA     . ALA   A 1 416 ? 243.074 239.049 178.368 1.00 56.77  ? 428 ALA   G CA     1 
ATOM   193  C C      . ALA   A 1 416 ? 241.920 239.012 179.364 1.00 60.52  ? 428 ALA   G C      1 
ATOM   194  O O      . ALA   A 1 416 ? 241.965 238.319 180.377 1.00 65.58  ? 428 ALA   G O      1 
ATOM   195  C CB     . ALA   A 1 416 ? 244.273 238.269 178.891 1.00 60.49  ? 428 ALA   G CB     1 
ATOM   196  N N      . PHE   A 1 417 ? 240.860 239.753 179.060 1.00 63.29  ? 429 PHE   G N      1 
ATOM   197  C CA     . PHE   A 1 417 ? 239.677 239.797 179.911 1.00 63.55  ? 429 PHE   G CA     1 
ATOM   198  C C      . PHE   A 1 417 ? 238.408 239.648 179.081 1.00 68.46  ? 429 PHE   G C      1 
ATOM   199  O O      . PHE   A 1 417 ? 238.459 239.614 177.852 1.00 69.86  ? 429 PHE   G O      1 
ATOM   200  C CB     . PHE   A 1 417 ? 239.630 241.101 180.708 1.00 58.32  ? 429 PHE   G CB     1 
ATOM   201  C CG     . PHE   A 1 417 ? 240.277 241.011 182.059 1.00 61.30  ? 429 PHE   G CG     1 
ATOM   202  C CD1    . PHE   A 1 417 ? 241.539 240.468 182.204 1.00 64.74  ? 429 PHE   G CD1    1 
ATOM   203  C CD2    . PHE   A 1 417 ? 239.621 241.468 183.185 1.00 68.03  ? 429 PHE   G CD2    1 
ATOM   204  C CE1    . PHE   A 1 417 ? 242.134 240.383 183.445 1.00 65.03  ? 429 PHE   G CE1    1 
ATOM   205  C CE2    . PHE   A 1 417 ? 240.213 241.385 184.428 1.00 66.96  ? 429 PHE   G CE2    1 
ATOM   206  C CZ     . PHE   A 1 417 ? 241.470 240.842 184.557 1.00 58.48  ? 429 PHE   G CZ     1 
ATOM   207  P P      . C     B 2 2   ? 220.776 260.606 229.781 1.00 65.95  ? 8   C     D P      1 
ATOM   208  O OP1    . C     B 2 2   ? 220.299 262.008 229.881 1.00 62.34  ? 8   C     D OP1    1 
ATOM   209  O OP2    . C     B 2 2   ? 221.263 260.084 228.480 1.00 62.73  ? 8   C     D OP2    1 
ATOM   210  O "O5'"  . C     B 2 2   ? 221.929 260.421 230.863 1.00 60.33  ? 8   C     D "O5'"  1 
ATOM   211  C "C5'"  . C     B 2 2   ? 221.877 261.117 232.097 1.00 58.56  ? 8   C     D "C5'"  1 
ATOM   212  C "C4'"  . C     B 2 2   ? 222.963 260.661 233.037 1.00 56.41  ? 8   C     D "C4'"  1 
ATOM   213  O "O4'"  . C     B 2 2   ? 222.938 259.218 233.152 1.00 56.26  ? 8   C     D "O4'"  1 
ATOM   214  C "C3'"  . C     B 2 2   ? 224.387 260.972 232.610 1.00 59.81  ? 8   C     D "C3'"  1 
ATOM   215  O "O3'"  . C     B 2 2   ? 224.766 262.302 232.912 1.00 63.01  ? 8   C     D "O3'"  1 
ATOM   216  C "C2'"  . C     B 2 2   ? 225.196 259.926 233.364 1.00 60.39  ? 8   C     D "C2'"  1 
ATOM   217  O "O2'"  . C     B 2 2   ? 225.374 260.313 234.718 1.00 63.54  ? 8   C     D "O2'"  1 
ATOM   218  C "C1'"  . C     B 2 2   ? 224.249 258.727 233.329 1.00 57.02  ? 8   C     D "C1'"  1 
ATOM   219  N N1     . C     B 2 2   ? 224.561 257.790 232.228 1.00 54.40  ? 8   C     D N1     1 
ATOM   220  C C2     . C     B 2 2   ? 225.660 256.942 232.368 1.00 53.24  ? 8   C     D C2     1 
ATOM   221  O O2     . C     B 2 2   ? 226.339 257.016 233.400 1.00 54.15  ? 8   C     D O2     1 
ATOM   222  N N3     . C     B 2 2   ? 225.958 256.071 231.379 1.00 52.43  ? 8   C     D N3     1 
ATOM   223  C C4     . C     B 2 2   ? 225.198 256.027 230.286 1.00 52.35  ? 8   C     D C4     1 
ATOM   224  N N4     . C     B 2 2   ? 225.528 255.154 229.334 1.00 53.74  ? 8   C     D N4     1 
ATOM   225  C C5     . C     B 2 2   ? 224.067 256.876 230.120 1.00 51.77  ? 8   C     D C5     1 
ATOM   226  C C6     . C     B 2 2   ? 223.786 257.733 231.107 1.00 54.22  ? 8   C     D C6     1 
ATOM   227  P P      . U     B 2 3   ? 225.799 263.089 231.968 1.00 62.63  ? 9   U     D P      1 
ATOM   228  O OP1    . U     B 2 3   ? 225.125 263.347 230.671 1.00 61.23  ? 9   U     D OP1    1 
ATOM   229  O OP2    . U     B 2 3   ? 227.098 262.372 231.998 1.00 54.88  ? 9   U     D OP2    1 
ATOM   230  O "O5'"  . U     B 2 3   ? 225.993 264.487 232.704 1.00 62.88  ? 9   U     D "O5'"  1 
ATOM   231  C "C5'"  . U     B 2 3   ? 225.043 265.534 232.549 1.00 61.71  ? 9   U     D "C5'"  1 
ATOM   232  C "C4'"  . U     B 2 3   ? 224.642 266.126 233.876 1.00 60.92  ? 9   U     D "C4'"  1 
ATOM   233  O "O4'"  . U     B 2 3   ? 224.300 267.527 233.688 1.00 61.18  ? 9   U     D "O4'"  1 
ATOM   234  C "C3'"  . U     B 2 3   ? 223.428 265.479 234.536 1.00 61.78  ? 9   U     D "C3'"  1 
ATOM   235  O "O3'"  . U     B 2 3   ? 223.572 265.538 235.953 1.00 63.44  ? 9   U     D "O3'"  1 
ATOM   236  C "C2'"  . U     B 2 3   ? 222.291 266.401 234.112 1.00 64.21  ? 9   U     D "C2'"  1 
ATOM   237  O "O2'"  . U     B 2 3   ? 221.162 266.371 234.959 1.00 68.71  ? 9   U     D "O2'"  1 
ATOM   238  C "C1'"  . U     B 2 3   ? 222.980 267.760 234.136 1.00 61.01  ? 9   U     D "C1'"  1 
ATOM   239  N N1     . U     B 2 3   ? 222.359 268.761 233.260 1.00 58.69  ? 9   U     D N1     1 
ATOM   240  C C2     . U     B 2 3   ? 222.605 268.687 231.904 1.00 60.85  ? 9   U     D C2     1 
ATOM   241  O O2     . U     B 2 3   ? 223.306 267.831 231.400 1.00 62.57  ? 9   U     D O2     1 
ATOM   242  N N3     . U     B 2 3   ? 221.989 269.655 231.153 1.00 61.32  ? 9   U     D N3     1 
ATOM   243  C C4     . U     B 2 3   ? 221.171 270.664 231.611 1.00 62.24  ? 9   U     D C4     1 
ATOM   244  O O4     . U     B 2 3   ? 220.692 271.462 230.807 1.00 64.66  ? 9   U     D O4     1 
ATOM   245  C C5     . U     B 2 3   ? 220.970 270.675 233.025 1.00 61.24  ? 9   U     D C5     1 
ATOM   246  C C6     . U     B 2 3   ? 221.557 269.745 233.782 1.00 59.57  ? 9   U     D C6     1 
ATOM   247  P P      . C     B 2 4   ? 224.003 264.233 236.781 1.00 64.75  ? 10  C     D P      1 
ATOM   248  O OP1    . C     B 2 4   ? 223.202 263.085 236.290 1.00 64.71  ? 10  C     D OP1    1 
ATOM   249  O OP2    . C     B 2 4   ? 223.981 264.584 238.222 1.00 62.26  ? 10  C     D OP2    1 
ATOM   250  O "O5'"  . C     B 2 4   ? 225.520 263.999 236.359 1.00 62.14  ? 10  C     D "O5'"  1 
ATOM   251  C "C5'"  . C     B 2 4   ? 226.511 263.727 237.340 1.00 64.86  ? 10  C     D "C5'"  1 
ATOM   252  C "C4'"  . C     B 2 4   ? 227.863 264.246 236.922 1.00 64.76  ? 10  C     D "C4'"  1 
ATOM   253  O "O4'"  . C     B 2 4   ? 227.700 265.547 236.295 1.00 63.71  ? 10  C     D "O4'"  1 
ATOM   254  C "C3'"  . C     B 2 4   ? 228.858 264.444 238.062 1.00 68.25  ? 10  C     D "C3'"  1 
ATOM   255  O "O3'"  . C     B 2 4   ? 230.177 264.178 237.593 1.00 73.15  ? 10  C     D "O3'"  1 
ATOM   256  C "C2'"  . C     B 2 4   ? 228.711 265.929 238.379 1.00 66.78  ? 10  C     D "C2'"  1 
ATOM   257  O "O2'"  . C     B 2 4   ? 229.838 266.512 238.997 1.00 69.54  ? 10  C     D "O2'"  1 
ATOM   258  C "C1'"  . C     B 2 4   ? 228.460 266.515 236.993 1.00 63.08  ? 10  C     D "C1'"  1 
ATOM   259  N N1     . C     B 2 4   ? 227.702 267.775 236.999 1.00 61.36  ? 10  C     D N1     1 
ATOM   260  C C2     . C     B 2 4   ? 228.398 268.980 236.908 1.00 60.94  ? 10  C     D C2     1 
ATOM   261  O O2     . C     B 2 4   ? 229.633 268.948 236.836 1.00 62.97  ? 10  C     D O2     1 
ATOM   262  N N3     . C     B 2 4   ? 227.713 270.146 236.908 1.00 59.32  ? 10  C     D N3     1 
ATOM   263  C C4     . C     B 2 4   ? 226.382 270.137 236.988 1.00 55.38  ? 10  C     D C4     1 
ATOM   264  N N4     . C     B 2 4   ? 225.744 271.308 236.985 1.00 51.05  ? 10  C     D N4     1 
ATOM   265  C C5     . C     B 2 4   ? 225.645 268.924 237.076 1.00 57.15  ? 10  C     D C5     1 
ATOM   266  C C6     . C     B 2 4   ? 226.338 267.779 237.076 1.00 62.06  ? 10  C     D C6     1 
ATOM   267  P P      . U     B 2 5   ? 230.875 262.765 237.902 1.00 79.92  ? 11  U     D P      1 
ATOM   268  O OP1    . U     B 2 5   ? 232.329 263.001 238.076 1.00 83.95  ? 11  U     D OP1    1 
ATOM   269  O OP2    . U     B 2 5   ? 230.414 261.783 236.890 1.00 75.50  ? 11  U     D OP2    1 
ATOM   270  O "O5'"  . U     B 2 5   ? 230.275 262.341 239.314 1.00 81.40  ? 11  U     D "O5'"  1 
ATOM   271  C "C5'"  . U     B 2 5   ? 230.768 262.922 240.510 1.00 80.34  ? 11  U     D "C5'"  1 
ATOM   272  C "C4'"  . U     B 2 5   ? 230.108 262.335 241.731 1.00 82.33  ? 11  U     D "C4'"  1 
ATOM   273  O "O4'"  . U     B 2 5   ? 228.697 262.673 241.749 1.00 81.24  ? 11  U     D "O4'"  1 
ATOM   274  C "C3'"  . U     B 2 5   ? 230.114 260.821 241.844 1.00 85.09  ? 11  U     D "C3'"  1 
ATOM   275  O "O3'"  . U     B 2 5   ? 231.352 260.293 242.279 1.00 90.28  ? 11  U     D "O3'"  1 
ATOM   276  C "C2'"  . U     B 2 5   ? 228.967 260.568 242.811 1.00 85.96  ? 11  U     D "C2'"  1 
ATOM   277  O "O2'"  . U     B 2 5   ? 229.362 260.863 244.143 1.00 88.01  ? 11  U     D "O2'"  1 
ATOM   278  C "C1'"  . U     B 2 5   ? 227.964 261.631 242.362 1.00 81.41  ? 11  U     D "C1'"  1 
ATOM   279  N N1     . U     B 2 5   ? 227.004 261.080 241.382 1.00 79.73  ? 11  U     D N1     1 
ATOM   280  C C2     . U     B 2 5   ? 225.738 260.781 241.835 1.00 82.28  ? 11  U     D C2     1 
ATOM   281  O O2     . U     B 2 5   ? 225.387 260.977 242.985 1.00 83.58  ? 11  U     D O2     1 
ATOM   282  N N3     . U     B 2 5   ? 224.892 260.259 240.888 1.00 84.65  ? 11  U     D N3     1 
ATOM   283  C C4     . U     B 2 5   ? 225.187 260.000 239.565 1.00 79.69  ? 11  U     D C4     1 
ATOM   284  O O4     . U     B 2 5   ? 224.318 259.526 238.832 1.00 80.06  ? 11  U     D O4     1 
ATOM   285  C C5     . U     B 2 5   ? 226.524 260.325 239.178 1.00 77.95  ? 11  U     D C5     1 
ATOM   286  C C6     . U     B 2 5   ? 227.367 260.837 240.080 1.00 80.92  ? 11  U     D C6     1 
ATOM   287  P P      . C     B 2 6   ? 231.787 258.809 241.845 1.00 99.31  ? 12  C     D P      1 
ATOM   288  O OP1    . C     B 2 6   ? 230.591 257.937 241.945 1.00 96.31  ? 12  C     D OP1    1 
ATOM   289  O OP2    . C     B 2 6   ? 233.024 258.444 242.578 1.00 105.13 ? 12  C     D OP2    1 
ATOM   290  O "O5'"  . C     B 2 6   ? 232.151 258.949 240.303 1.00 96.12  ? 12  C     D "O5'"  1 
ATOM   291  C "C5'"  . C     B 2 6   ? 232.918 260.050 239.829 1.00 98.48  ? 12  C     D "C5'"  1 
ATOM   292  C "C4'"  . C     B 2 6   ? 234.259 259.601 239.308 1.00 104.60 ? 12  C     D "C4'"  1 
ATOM   293  O "O4'"  . C     B 2 6   ? 235.297 260.147 240.164 1.00 106.81 ? 12  C     D "O4'"  1 
ATOM   294  C "C3'"  . C     B 2 6   ? 234.461 258.088 239.290 1.00 111.67 ? 12  C     D "C3'"  1 
ATOM   295  O "O3'"  . C     B 2 6   ? 235.180 257.678 238.119 1.00 119.64 ? 12  C     D "O3'"  1 
ATOM   296  C "C2'"  . C     B 2 6   ? 235.262 257.826 240.567 1.00 113.06 ? 12  C     D "C2'"  1 
ATOM   297  O "O2'"  . C     B 2 6   ? 236.077 256.673 240.527 1.00 114.53 ? 12  C     D "O2'"  1 
ATOM   298  C "C1'"  . C     B 2 6   ? 236.089 259.105 240.702 1.00 113.54 ? 12  C     D "C1'"  1 
ATOM   299  N N1     . C     B 2 6   ? 236.400 259.460 242.094 1.00 113.00 ? 12  C     D N1     1 
ATOM   300  C C2     . C     B 2 6   ? 237.274 260.520 242.337 1.00 110.35 ? 12  C     D C2     1 
ATOM   301  O O2     . C     B 2 6   ? 237.753 261.133 241.373 1.00 107.90 ? 12  C     D O2     1 
ATOM   302  N N3     . C     B 2 6   ? 237.561 260.856 243.615 1.00 109.84 ? 12  C     D N3     1 
ATOM   303  C C4     . C     B 2 6   ? 237.018 260.171 244.623 1.00 111.12 ? 12  C     D C4     1 
ATOM   304  N N4     . C     B 2 6   ? 237.331 260.536 245.867 1.00 112.97 ? 12  C     D N4     1 
ATOM   305  C C5     . C     B 2 6   ? 236.127 259.083 244.404 1.00 109.45 ? 12  C     D C5     1 
ATOM   306  C C6     . C     B 2 6   ? 235.852 258.763 243.134 1.00 110.77 ? 12  C     D C6     1 
ATOM   307  P P      . U     B 2 7   ? 236.681 258.170 237.812 1.00 126.43 ? 13  U     D P      1 
ATOM   308  O OP1    . U     B 2 7   ? 236.764 259.637 238.025 1.00 115.73 ? 13  U     D OP1    1 
ATOM   309  O OP2    . U     B 2 7   ? 237.069 257.612 236.492 1.00 125.23 ? 13  U     D OP2    1 
ATOM   310  O "O5'"  . U     B 2 7   ? 237.558 257.436 238.920 1.00 121.13 ? 13  U     D "O5'"  1 
ATOM   311  C "C5'"  . U     B 2 7   ? 238.885 257.013 238.644 1.00 117.60 ? 13  U     D "C5'"  1 
ATOM   312  C "C4'"  . U     B 2 7   ? 239.886 257.811 239.437 1.00 115.39 ? 13  U     D "C4'"  1 
ATOM   313  O "O4'"  . U     B 2 7   ? 239.215 258.489 240.530 1.00 115.55 ? 13  U     D "O4'"  1 
ATOM   314  C "C3'"  . U     B 2 7   ? 240.986 257.015 240.119 1.00 115.17 ? 13  U     D "C3'"  1 
ATOM   315  O "O3'"  . U     B 2 7   ? 242.045 256.668 239.246 1.00 118.10 ? 13  U     D "O3'"  1 
ATOM   316  C "C2'"  . U     B 2 7   ? 241.405 257.938 241.253 1.00 116.09 ? 13  U     D "C2'"  1 
ATOM   317  O "O2'"  . U     B 2 7   ? 242.231 258.985 240.766 1.00 117.60 ? 13  U     D "O2'"  1 
ATOM   318  C "C1'"  . U     B 2 7   ? 240.060 258.537 241.660 1.00 114.99 ? 13  U     D "C1'"  1 
ATOM   319  N N1     . U     B 2 7   ? 239.423 257.766 242.748 1.00 115.66 ? 13  U     D N1     1 
ATOM   320  C C2     . U     B 2 7   ? 239.678 258.151 244.048 1.00 115.92 ? 13  U     D C2     1 
ATOM   321  O O2     . U     B 2 7   ? 240.393 259.095 244.330 1.00 116.58 ? 13  U     D O2     1 
ATOM   322  N N3     . U     B 2 7   ? 239.056 257.392 245.007 1.00 117.24 ? 13  U     D N3     1 
ATOM   323  C C4     . U     B 2 7   ? 238.228 256.309 244.801 1.00 117.99 ? 13  U     D C4     1 
ATOM   324  O O4     . U     B 2 7   ? 237.744 255.725 245.771 1.00 120.25 ? 13  U     D O4     1 
ATOM   325  C C5     . U     B 2 7   ? 238.017 255.972 243.427 1.00 116.51 ? 13  U     D C5     1 
ATOM   326  C C6     . U     B 2 7   ? 238.609 256.694 242.472 1.00 115.31 ? 13  U     D C6     1 
ATOM   327  P P      . C     B 2 8   ? 243.147 255.595 239.708 1.00 115.64 ? 14  C     D P      1 
ATOM   328  O OP1    . C     B 2 8   ? 244.482 256.169 239.409 1.00 112.56 ? 14  C     D OP1    1 
ATOM   329  O OP2    . C     B 2 8   ? 242.780 254.265 239.161 1.00 112.31 ? 14  C     D OP2    1 
ATOM   330  O "O5'"  . C     B 2 8   ? 242.980 255.543 241.290 1.00 114.29 ? 14  C     D "O5'"  1 
ATOM   331  C "C5'"  . C     B 2 8   ? 243.649 254.556 242.065 1.00 112.17 ? 14  C     D "C5'"  1 
ATOM   332  C "C4'"  . C     B 2 8   ? 245.081 254.944 242.332 1.00 112.04 ? 14  C     D "C4'"  1 
ATOM   333  O "O4'"  . C     B 2 8   ? 245.199 256.392 242.290 1.00 116.43 ? 14  C     D "O4'"  1 
ATOM   334  C "C3'"  . C     B 2 8   ? 245.631 254.513 243.688 1.00 112.05 ? 14  C     D "C3'"  1 
ATOM   335  O "O3'"  . C     B 2 8   ? 247.024 254.239 243.562 1.00 108.78 ? 14  C     D "O3'"  1 
ATOM   336  C "C2'"  . C     B 2 8   ? 245.438 255.765 244.535 1.00 117.48 ? 14  C     D "C2'"  1 
ATOM   337  O "O2'"  . C     B 2 8   ? 246.292 255.853 245.655 1.00 122.97 ? 14  C     D "O2'"  1 
ATOM   338  C "C1'"  . C     B 2 8   ? 245.727 256.860 243.515 1.00 120.35 ? 14  C     D "C1'"  1 
ATOM   339  N N1     . C     B 2 8   ? 245.105 258.155 243.822 1.00 126.64 ? 14  C     D N1     1 
ATOM   340  C C2     . C     B 2 8   ? 245.909 259.173 244.338 1.00 131.54 ? 14  C     D C2     1 
ATOM   341  O O2     . C     B 2 8   ? 247.113 258.946 244.527 1.00 131.26 ? 14  C     D O2     1 
ATOM   342  N N3     . C     B 2 8   ? 245.355 260.374 244.624 1.00 134.75 ? 14  C     D N3     1 
ATOM   343  C C4     . C     B 2 8   ? 244.055 260.574 244.406 1.00 133.44 ? 14  C     D C4     1 
ATOM   344  N N4     . C     B 2 8   ? 243.550 261.774 244.701 1.00 134.78 ? 14  C     D N4     1 
ATOM   345  C C5     . C     B 2 8   ? 243.215 259.554 243.875 1.00 128.73 ? 14  C     D C5     1 
ATOM   346  C C6     . C     B 2 8   ? 243.774 258.369 243.599 1.00 125.26 ? 14  C     D C6     1 
ATOM   347  P P      . U     B 2 9   ? 247.556 252.724 243.569 1.00 116.55 ? 15  U     D P      1 
ATOM   348  O OP1    . U     B 2 9   ? 246.421 251.835 243.925 1.00 118.62 ? 15  U     D OP1    1 
ATOM   349  O OP2    . U     B 2 9   ? 248.805 252.683 244.370 1.00 114.09 ? 15  U     D OP2    1 
ATOM   350  O "O5'"  . U     B 2 9   ? 247.939 252.454 242.048 1.00 99.89  ? 15  U     D "O5'"  1 
ATOM   351  C "C5'"  . U     B 2 9   ? 248.488 253.489 241.249 1.00 87.14  ? 15  U     D "C5'"  1 
ATOM   352  C "C4'"  . U     B 2 9   ? 247.939 253.457 239.846 1.00 82.66  ? 15  U     D "C4'"  1 
ATOM   353  O "O4'"  . U     B 2 9   ? 248.211 254.720 239.195 1.00 80.39  ? 15  U     D "O4'"  1 
ATOM   354  C "C3'"  . U     B 2 9   ? 248.539 252.414 238.914 1.00 76.16  ? 15  U     D "C3'"  1 
ATOM   355  O "O3'"  . U     B 2 9   ? 247.935 251.141 239.068 1.00 76.49  ? 15  U     D "O3'"  1 
ATOM   356  C "C2'"  . U     B 2 9   ? 248.317 253.022 237.536 1.00 75.69  ? 15  U     D "C2'"  1 
ATOM   357  O "O2'"  . U     B 2 9   ? 246.990 252.785 237.094 1.00 78.20  ? 15  U     D "O2'"  1 
ATOM   358  C "C1'"  . U     B 2 9   ? 248.475 254.516 237.826 1.00 75.39  ? 15  U     D "C1'"  1 
ATOM   359  N N1     . U     B 2 9   ? 249.840 255.010 237.542 1.00 69.53  ? 15  U     D N1     1 
ATOM   360  C C2     . U     B 2 9   ? 249.978 255.973 236.566 1.00 68.52  ? 15  U     D C2     1 
ATOM   361  O O2     . U     B 2 9   ? 249.031 256.421 235.947 1.00 71.53  ? 15  U     D O2     1 
ATOM   362  N N3     . U     B 2 9   ? 251.262 256.405 236.351 1.00 63.79  ? 15  U     D N3     1 
ATOM   363  C C4     . U     B 2 9   ? 252.398 255.968 236.995 1.00 64.58  ? 15  U     D C4     1 
ATOM   364  O O4     . U     B 2 9   ? 253.487 256.448 236.686 1.00 63.38  ? 15  U     D O4     1 
ATOM   365  C C5     . U     B 2 9   ? 252.173 254.968 237.990 1.00 67.52  ? 15  U     D C5     1 
ATOM   366  C C6     . U     B 2 9   ? 250.932 254.534 238.224 1.00 69.47  ? 15  U     D C6     1 
ATOM   367  P P      . C     B 2 10  ? 248.726 249.804 238.661 1.00 74.65  ? 16  C     D P      1 
ATOM   368  O OP1    . C     B 2 10  ? 247.774 248.671 238.776 1.00 74.22  ? 16  C     D OP1    1 
ATOM   369  O OP2    . C     B 2 10  ? 250.001 249.765 239.418 1.00 75.39  ? 16  C     D OP2    1 
ATOM   370  O "O5'"  . C     B 2 10  ? 249.057 250.001 237.116 1.00 66.95  ? 16  C     D "O5'"  1 
ATOM   371  C "C5'"  . C     B 2 10  ? 248.021 250.000 236.141 1.00 66.95  ? 16  C     D "C5'"  1 
ATOM   372  C "C4'"  . C     B 2 10  ? 248.510 249.502 234.804 1.00 68.31  ? 16  C     D "C4'"  1 
ATOM   373  O "O4'"  . C     B 2 10  ? 249.581 250.364 234.330 1.00 71.13  ? 16  C     D "O4'"  1 
ATOM   374  C "C3'"  . C     B 2 10  ? 249.076 248.083 234.800 1.00 66.33  ? 16  C     D "C3'"  1 
ATOM   375  O "O3'"  . C     B 2 10  ? 248.785 247.470 233.545 1.00 68.46  ? 16  C     D "O3'"  1 
ATOM   376  C "C2'"  . C     B 2 10  ? 250.577 248.327 234.907 1.00 66.72  ? 16  C     D "C2'"  1 
ATOM   377  O "O2'"  . C     B 2 10  ? 251.383 247.273 234.425 1.00 69.21  ? 16  C     D "O2'"  1 
ATOM   378  C "C1'"  . C     B 2 10  ? 250.733 249.586 234.065 1.00 66.43  ? 16  C     D "C1'"  1 
ATOM   379  N N1     . C     B 2 10  ? 251.923 250.389 234.380 1.00 62.98  ? 16  C     D N1     1 
ATOM   380  C C2     . C     B 2 10  ? 252.947 250.445 233.433 1.00 61.88  ? 16  C     D C2     1 
ATOM   381  O O2     . C     B 2 10  ? 252.817 249.812 232.378 1.00 61.51  ? 16  C     D O2     1 
ATOM   382  N N3     . C     B 2 10  ? 254.049 251.182 233.690 1.00 60.49  ? 16  C     D N3     1 
ATOM   383  C C4     . C     B 2 10  ? 254.146 251.847 234.841 1.00 61.26  ? 16  C     D C4     1 
ATOM   384  N N4     . C     B 2 10  ? 255.251 252.561 235.056 1.00 57.98  ? 16  C     D N4     1 
ATOM   385  C C5     . C     B 2 10  ? 253.117 251.811 235.824 1.00 62.83  ? 16  C     D C5     1 
ATOM   386  C C6     . C     B 2 10  ? 252.031 251.076 235.555 1.00 62.56  ? 16  C     D C6     1 
ATOM   387  P P      . U     B 2 11  ? 247.660 246.327 233.439 1.00 69.85  ? 17  U     D P      1 
ATOM   388  O OP1    . U     B 2 11  ? 246.969 246.473 232.135 1.00 67.81  ? 17  U     D OP1    1 
ATOM   389  O OP2    . U     B 2 11  ? 246.869 246.324 234.693 1.00 69.61  ? 17  U     D OP2    1 
ATOM   390  O "O5'"  . U     B 2 11  ? 248.501 244.979 233.385 1.00 66.90  ? 17  U     D "O5'"  1 
ATOM   391  C "C5'"  . U     B 2 11  ? 249.852 244.952 233.827 1.00 67.75  ? 17  U     D "C5'"  1 
ATOM   392  C "C4'"  . U     B 2 11  ? 250.313 243.548 234.112 1.00 68.45  ? 17  U     D "C4'"  1 
ATOM   393  O "O4'"  . U     B 2 11  ? 249.888 242.691 233.022 1.00 69.42  ? 17  U     D "O4'"  1 
ATOM   394  C "C3'"  . U     B 2 11  ? 251.822 243.375 234.234 1.00 69.96  ? 17  U     D "C3'"  1 
ATOM   395  O "O3'"  . U     B 2 11  ? 252.116 242.377 235.208 1.00 72.74  ? 17  U     D "O3'"  1 
ATOM   396  C "C2'"  . U     B 2 11  ? 252.221 242.882 232.847 1.00 71.58  ? 17  U     D "C2'"  1 
ATOM   397  O "O2'"  . U     B 2 11  ? 253.412 242.124 232.814 1.00 74.78  ? 17  U     D "O2'"  1 
ATOM   398  C "C1'"  . U     B 2 11  ? 251.006 242.050 232.444 1.00 69.08  ? 17  U     D "C1'"  1 
ATOM   399  N N1     . U     B 2 11  ? 250.795 242.001 230.989 1.00 65.57  ? 17  U     D N1     1 
ATOM   400  C C2     . U     B 2 11  ? 249.506 241.917 230.497 1.00 67.25  ? 17  U     D C2     1 
ATOM   401  O O2     . U     B 2 11  ? 248.513 241.895 231.200 1.00 71.96  ? 17  U     D O2     1 
ATOM   402  N N3     . U     B 2 11  ? 249.409 241.879 229.129 1.00 65.53  ? 17  U     D N3     1 
ATOM   403  C C4     . U     B 2 11  ? 250.443 241.901 228.219 1.00 66.40  ? 17  U     D C4     1 
ATOM   404  O O4     . U     B 2 11  ? 250.193 241.853 227.015 1.00 68.73  ? 17  U     D O4     1 
ATOM   405  C C5     . U     B 2 11  ? 251.743 241.976 228.804 1.00 64.66  ? 17  U     D C5     1 
ATOM   406  C C6     . U     B 2 11  ? 251.869 242.020 230.133 1.00 65.22  ? 17  U     D C6     1 
ATOM   407  P P      . C     B 2 12  ? 252.685 242.806 236.649 1.00 78.50  ? 18  C     D P      1 
ATOM   408  O OP1    . C     B 2 12  ? 253.118 241.550 237.378 1.00 80.84  ? 18  C     D OP1    1 
ATOM   409  O "O5'"  . C     B 2 12  ? 253.990 243.654 236.309 1.00 71.02  ? 18  C     D "O5'"  1 
ATOM   410  C "C5'"  . C     B 2 12  ? 254.780 244.232 237.338 1.00 69.43  ? 18  C     D "C5'"  1 
ATOM   411  C "C4'"  . C     B 2 12  ? 255.690 245.302 236.792 1.00 68.39  ? 18  C     D "C4'"  1 
ATOM   412  O "O4'"  . C     B 2 12  ? 254.896 246.402 236.268 1.00 68.76  ? 18  C     D "O4'"  1 
ATOM   413  C "C3'"  . C     B 2 12  ? 256.622 245.979 237.783 1.00 67.28  ? 18  C     D "C3'"  1 
ATOM   414  O "O3'"  . C     B 2 12  ? 257.773 245.221 238.105 1.00 67.42  ? 18  C     D "O3'"  1 
ATOM   415  C "C2'"  . C     B 2 12  ? 256.929 247.290 237.081 1.00 69.45  ? 18  C     D "C2'"  1 
ATOM   416  O "O2'"  . C     B 2 12  ? 257.806 247.060 235.989 1.00 75.86  ? 18  C     D "O2'"  1 
ATOM   417  C "C1'"  . C     B 2 12  ? 255.555 247.628 236.517 1.00 67.67  ? 18  C     D "C1'"  1 
ATOM   418  N N1     . C     B 2 12  ? 254.763 248.434 237.474 1.00 65.75  ? 18  C     D N1     1 
ATOM   419  C C2     . C     B 2 12  ? 253.371 248.312 237.492 1.00 65.80  ? 18  C     D C2     1 
ATOM   420  O O2     . C     B 2 12  ? 252.826 247.526 236.701 1.00 67.66  ? 18  C     D O2     1 
ATOM   421  N N3     . C     B 2 12  ? 252.658 249.057 238.370 1.00 63.61  ? 18  C     D N3     1 
ATOM   422  C C4     . C     B 2 12  ? 253.276 249.898 239.208 1.00 62.84  ? 18  C     D C4     1 
ATOM   423  N N4     . C     B 2 12  ? 252.527 250.600 240.046 1.00 64.44  ? 18  C     D N4     1 
ATOM   424  C C5     . C     B 2 12  ? 254.689 250.036 239.203 1.00 64.60  ? 18  C     D C5     1 
ATOM   425  C C6     . C     B 2 12  ? 255.386 249.294 238.330 1.00 64.98  ? 18  C     D C6     1 
ATOM   426  O OP3    . U     C 2 1   ? 263.300 259.128 226.537 1.00 81.36  ? 1   U     E OP3    1 
ATOM   427  P P      . U     C 2 1   ? 263.114 260.295 227.426 1.00 85.96  ? 1   U     E P      1 
ATOM   428  O OP1    . U     C 2 1   ? 263.890 260.036 228.661 1.00 83.21  ? 1   U     E OP1    1 
ATOM   429  O OP2    . U     C 2 1   ? 261.661 260.564 227.531 1.00 65.56  ? 1   U     E OP2    1 
ATOM   430  O "O5'"  . U     C 2 1   ? 263.763 261.565 226.720 1.00 79.40  ? 1   U     E "O5'"  1 
ATOM   431  C "C5'"  . U     C 2 1   ? 263.000 262.745 226.491 1.00 66.45  ? 1   U     E "C5'"  1 
ATOM   432  C "C4'"  . U     C 2 1   ? 263.711 263.688 225.551 1.00 64.96  ? 1   U     E "C4'"  1 
ATOM   433  O "O4'"  . U     C 2 1   ? 265.005 264.031 226.118 1.00 62.34  ? 1   U     E "O4'"  1 
ATOM   434  C "C3'"  . U     C 2 1   ? 263.994 263.123 224.162 1.00 64.61  ? 1   U     E "C3'"  1 
ATOM   435  O "O3'"  . U     C 2 1   ? 263.972 264.182 223.207 1.00 66.00  ? 1   U     E "O3'"  1 
ATOM   436  C "C2'"  . U     C 2 1   ? 265.420 262.606 224.303 1.00 63.80  ? 1   U     E "C2'"  1 
ATOM   437  O "O2'"  . U     C 2 1   ? 266.127 262.491 223.088 1.00 67.92  ? 1   U     E "O2'"  1 
ATOM   438  C "C1'"  . U     C 2 1   ? 266.032 263.663 225.216 1.00 62.06  ? 1   U     E "C1'"  1 
ATOM   439  N N1     . U     C 2 1   ? 267.183 263.188 225.996 1.00 62.83  ? 1   U     E N1     1 
ATOM   440  C C2     . U     C 2 1   ? 268.324 263.957 225.964 1.00 64.15  ? 1   U     E C2     1 
ATOM   441  O O2     . U     C 2 1   ? 268.397 264.995 225.329 1.00 65.58  ? 1   U     E O2     1 
ATOM   442  N N3     . U     C 2 1   ? 269.372 263.475 226.703 1.00 60.09  ? 1   U     E N3     1 
ATOM   443  C C4     . U     C 2 1   ? 269.390 262.320 227.452 1.00 58.27  ? 1   U     E C4     1 
ATOM   444  O O4     . U     C 2 1   ? 270.412 262.015 228.064 1.00 60.67  ? 1   U     E O4     1 
ATOM   445  C C5     . U     C 2 1   ? 268.171 261.575 227.432 1.00 57.93  ? 1   U     E C5     1 
ATOM   446  C C6     . U     C 2 1   ? 267.133 262.023 226.720 1.00 62.93  ? 1   U     E C6     1 
ATOM   447  P P      . C     C 2 2   ? 262.632 264.525 222.391 1.00 65.80  ? 2   C     E P      1 
ATOM   448  O OP1    . C     C 2 2   ? 262.888 265.774 221.630 1.00 59.17  ? 2   C     E OP1    1 
ATOM   449  O OP2    . C     C 2 2   ? 261.480 264.473 223.325 1.00 61.69  ? 2   C     E OP2    1 
ATOM   450  O "O5'"  . C     C 2 2   ? 262.485 263.322 221.356 1.00 61.87  ? 2   C     E "O5'"  1 
ATOM   451  C "C5'"  . C     C 2 2   ? 263.450 263.109 220.338 1.00 59.02  ? 2   C     E "C5'"  1 
ATOM   452  C "C4'"  . C     C 2 2   ? 262.827 262.587 219.067 1.00 59.59  ? 2   C     E "C4'"  1 
ATOM   453  O "O4'"  . C     C 2 2   ? 262.329 261.243 219.259 1.00 60.40  ? 2   C     E "O4'"  1 
ATOM   454  C "C3'"  . C     C 2 2   ? 261.628 263.356 218.539 1.00 59.44  ? 2   C     E "C3'"  1 
ATOM   455  O "O3'"  . C     C 2 2   ? 262.015 264.511 217.819 1.00 59.40  ? 2   C     E "O3'"  1 
ATOM   456  C "C2'"  . C     C 2 2   ? 260.909 262.323 217.677 1.00 62.80  ? 2   C     E "C2'"  1 
ATOM   457  O "O2'"  . C     C 2 2   ? 261.492 262.259 216.384 1.00 66.72  ? 2   C     E "O2'"  1 
ATOM   458  C "C1'"  . C     C 2 2   ? 261.227 261.015 218.409 1.00 57.57  ? 2   C     E "C1'"  1 
ATOM   459  N N1     . C     C 2 2   ? 260.096 260.474 219.199 1.00 56.87  ? 2   C     E N1     1 
ATOM   460  C C2     . C     C 2 2   ? 259.847 260.926 220.495 1.00 60.61  ? 2   C     E C2     1 
ATOM   461  O O2     . C     C 2 2   ? 260.573 261.801 220.981 1.00 64.19  ? 2   C     E O2     1 
ATOM   462  N N3     . C     C 2 2   ? 258.819 260.399 221.197 1.00 55.82  ? 2   C     E N3     1 
ATOM   463  C C4     . C     C 2 2   ? 258.052 259.457 220.652 1.00 51.03  ? 2   C     E C4     1 
ATOM   464  N N4     . C     C 2 2   ? 257.048 258.968 221.381 1.00 50.30  ? 2   C     E N4     1 
ATOM   465  C C5     . C     C 2 2   ? 258.281 258.973 219.336 1.00 51.25  ? 2   C     E C5     1 
ATOM   466  C C6     . C     C 2 2   ? 259.305 259.501 218.656 1.00 53.43  ? 2   C     E C6     1 
ATOM   467  P P      . U     C 2 3   ? 260.948 265.663 217.487 1.00 81.98  ? 3   U     E P      1 
ATOM   468  O OP1    . U     C 2 3   ? 261.680 266.772 216.826 1.00 74.93  ? 3   U     E OP1    1 
ATOM   469  O OP2    . U     C 2 3   ? 260.155 265.929 218.712 1.00 80.34  ? 3   U     E OP2    1 
ATOM   470  O "O5'"  . U     C 2 3   ? 259.992 265.000 216.401 1.00 60.99  ? 3   U     E "O5'"  1 
ATOM   471  C "C5'"  . U     C 2 3   ? 260.502 264.574 215.148 1.00 59.45  ? 3   U     E "C5'"  1 
ATOM   472  C "C4'"  . U     C 2 3   ? 259.498 263.737 214.400 1.00 59.88  ? 3   U     E "C4'"  1 
ATOM   473  O "O4'"  . U     C 2 3   ? 259.217 262.526 215.144 1.00 54.54  ? 3   U     E "O4'"  1 
ATOM   474  C "C3'"  . U     C 2 3   ? 258.133 264.371 214.191 1.00 60.70  ? 3   U     E "C3'"  1 
ATOM   475  O "O3'"  . U     C 2 3   ? 258.118 265.252 213.083 1.00 60.53  ? 3   U     E "O3'"  1 
ATOM   476  C "C2'"  . U     C 2 3   ? 257.220 263.165 214.024 1.00 59.26  ? 3   U     E "C2'"  1 
ATOM   477  O "O2'"  . U     C 2 3   ? 257.305 262.655 212.702 1.00 57.83  ? 3   U     E "O2'"  1 
ATOM   478  C "C1'"  . U     C 2 3   ? 257.869 262.152 214.969 1.00 53.34  ? 3   U     E "C1'"  1 
ATOM   479  N N1     . U     C 2 3   ? 257.224 262.098 216.300 1.00 55.11  ? 3   U     E N1     1 
ATOM   480  C C2     . U     C 2 3   ? 256.223 261.169 216.487 1.00 55.09  ? 3   U     E C2     1 
ATOM   481  O O2     . U     C 2 3   ? 255.848 260.421 215.603 1.00 55.82  ? 3   U     E O2     1 
ATOM   482  N N3     . U     C 2 3   ? 255.677 261.153 217.745 1.00 51.83  ? 3   U     E N3     1 
ATOM   483  C C4     . U     C 2 3   ? 256.027 261.953 218.812 1.00 48.88  ? 3   U     E C4     1 
ATOM   484  O O4     . U     C 2 3   ? 255.441 261.819 219.885 1.00 53.44  ? 3   U     E O4     1 
ATOM   485  C C5     . U     C 2 3   ? 257.075 262.885 218.541 1.00 51.41  ? 3   U     E C5     1 
ATOM   486  C C6     . U     C 2 3   ? 257.626 262.921 217.324 1.00 58.90  ? 3   U     E C6     1 
ATOM   487  P P      . C     C 2 4   ? 256.864 266.221 212.831 1.00 67.75  ? 4   C     E P      1 
ATOM   488  O OP1    . C     C 2 4   ? 257.218 267.120 211.705 1.00 61.12  ? 4   C     E OP1    1 
ATOM   489  O OP2    . C     C 2 4   ? 256.446 266.804 214.130 1.00 65.63  ? 4   C     E OP2    1 
ATOM   490  O "O5'"  . C     C 2 4   ? 255.720 265.232 212.336 1.00 61.54  ? 4   C     E "O5'"  1 
ATOM   491  C "C5'"  . C     C 2 4   ? 255.857 264.518 211.119 1.00 54.89  ? 4   C     E "C5'"  1 
ATOM   492  C "C4'"  . C     C 2 4   ? 254.666 263.632 210.865 1.00 55.80  ? 4   C     E "C4'"  1 
ATOM   493  O "O4'"  . C     C 2 4   ? 254.632 262.557 211.836 1.00 59.02  ? 4   C     E "O4'"  1 
ATOM   494  C "C3'"  . C     C 2 4   ? 253.306 264.292 211.000 1.00 55.48  ? 4   C     E "C3'"  1 
ATOM   495  O "O3'"  . C     C 2 4   ? 252.944 265.033 209.849 1.00 59.79  ? 4   C     E "O3'"  1 
ATOM   496  C "C2'"  . C     C 2 4   ? 252.389 263.109 211.283 1.00 54.52  ? 4   C     E "C2'"  1 
ATOM   497  O "O2'"  . C     C 2 4   ? 252.084 262.415 210.084 1.00 56.62  ? 4   C     E "O2'"  1 
ATOM   498  C "C1'"  . C     C 2 4   ? 253.295 262.220 212.136 1.00 55.80  ? 4   C     E "C1'"  1 
ATOM   499  N N1     . C     C 2 4   ? 253.074 262.416 213.586 1.00 54.87  ? 4   C     E N1     1 
ATOM   500  C C2     . C     C 2 4   ? 252.136 261.614 214.235 1.00 54.48  ? 4   C     E C2     1 
ATOM   501  O O2     . C     C 2 4   ? 251.518 260.769 213.575 1.00 56.94  ? 4   C     E O2     1 
ATOM   502  N N3     . C     C 2 4   ? 251.929 261.780 215.559 1.00 49.05  ? 4   C     E N3     1 
ATOM   503  C C4     . C     C 2 4   ? 252.618 262.701 216.230 1.00 51.67  ? 4   C     E C4     1 
ATOM   504  N N4     . C     C 2 4   ? 252.378 262.831 217.535 1.00 56.18  ? 4   C     E N4     1 
ATOM   505  C C5     . C     C 2 4   ? 253.581 263.533 215.594 1.00 54.39  ? 4   C     E C5     1 
ATOM   506  C C6     . C     C 2 4   ? 253.776 263.357 214.283 1.00 56.22  ? 4   C     E C6     1 
ATOM   507  P P      . U     C 2 5   ? 252.243 266.470 209.997 1.00 69.90  ? 5   U     E P      1 
ATOM   508  O OP1    . U     C 2 5   ? 252.439 267.212 208.727 1.00 61.94  ? 5   U     E OP1    1 
ATOM   509  O OP2    . U     C 2 5   ? 252.689 267.073 211.277 1.00 57.74  ? 5   U     E OP2    1 
ATOM   510  O "O5'"  . U     C 2 5   ? 250.695 266.125 210.118 1.00 60.50  ? 5   U     E "O5'"  1 
ATOM   511  C "C5'"  . U     C 2 5   ? 250.075 265.260 209.180 1.00 53.15  ? 5   U     E "C5'"  1 
ATOM   512  C "C4'"  . U     C 2 5   ? 249.000 264.426 209.824 1.00 52.52  ? 5   U     E "C4'"  1 
ATOM   513  O "O4'"  . U     C 2 5   ? 247.891 265.274 210.209 1.00 55.50  ? 5   U     E "O4'"  1 
ATOM   514  C "C3'"  . U     C 2 5   ? 248.371 263.366 208.934 1.00 53.38  ? 5   U     E "C3'"  1 
ATOM   515  O "O3'"  . U     C 2 5   ? 249.139 262.178 208.890 1.00 60.23  ? 5   U     E "O3'"  1 
ATOM   516  C "C2'"  . U     C 2 5   ? 246.995 263.173 209.555 1.00 53.10  ? 5   U     E "C2'"  1 
ATOM   517  O "O2'"  . U     C 2 5   ? 247.075 262.331 210.695 1.00 59.99  ? 5   U     E "O2'"  1 
ATOM   518  C "C1'"  . U     C 2 5   ? 246.672 264.589 210.027 1.00 52.98  ? 5   U     E "C1'"  1 
ATOM   519  N N1     . U     C 2 5   ? 245.852 265.350 209.060 1.00 53.48  ? 5   U     E N1     1 
ATOM   520  C C2     . U     C 2 5   ? 244.528 265.000 208.900 1.00 51.28  ? 5   U     E C2     1 
ATOM   521  O O2     . U     C 2 5   ? 244.012 264.074 209.499 1.00 49.55  ? 5   U     E O2     1 
ATOM   522  N N3     . U     C 2 5   ? 243.835 265.767 207.999 1.00 51.44  ? 5   U     E N3     1 
ATOM   523  C C4     . U     C 2 5   ? 244.319 266.831 207.267 1.00 50.63  ? 5   U     E C4     1 
ATOM   524  O O4     . U     C 2 5   ? 243.570 267.425 206.494 1.00 50.36  ? 5   U     E O4     1 
ATOM   525  C C5     . U     C 2 5   ? 245.695 267.138 207.498 1.00 48.78  ? 5   U     E C5     1 
ATOM   526  C C6     . U     C 2 5   ? 246.393 266.407 208.369 1.00 54.16  ? 5   U     E C6     1 
ATOM   527  P P      . C     C 2 6   ? 249.368 261.410 207.499 1.00 66.36  ? 6   C     E P      1 
ATOM   528  O OP1    . C     C 2 6   ? 250.143 260.179 207.791 1.00 61.59  ? 6   C     E OP1    1 
ATOM   529  O OP2    . C     C 2 6   ? 249.889 262.383 206.508 1.00 65.90  ? 6   C     E OP2    1 
ATOM   530  O "O5'"  . C     C 2 6   ? 247.899 260.979 207.062 1.00 61.30  ? 6   C     E "O5'"  1 
ATOM   531  C "C5'"  . C     C 2 6   ? 247.149 260.061 207.842 1.00 53.80  ? 6   C     E "C5'"  1 
ATOM   532  C "C4'"  . C     C 2 6   ? 245.735 259.938 207.338 1.00 54.64  ? 6   C     E "C4'"  1 
ATOM   533  O "O4'"  . C     C 2 6   ? 245.056 261.214 207.465 1.00 58.58  ? 6   C     E "O4'"  1 
ATOM   534  C "C3'"  . C     C 2 6   ? 245.581 259.588 205.869 1.00 57.01  ? 6   C     E "C3'"  1 
ATOM   535  O "O3'"  . C     C 2 6   ? 245.749 258.208 205.603 1.00 60.98  ? 6   C     E "O3'"  1 
ATOM   536  C "C2'"  . C     C 2 6   ? 244.188 260.112 205.550 1.00 56.64  ? 6   C     E "C2'"  1 
ATOM   537  O "O2'"  . C     C 2 6   ? 243.195 259.223 206.036 1.00 59.92  ? 6   C     E "O2'"  1 
ATOM   538  C "C1'"  . C     C 2 6   ? 244.149 261.384 206.395 1.00 54.47  ? 6   C     E "C1'"  1 
ATOM   539  N N1     . C     C 2 6   ? 244.550 262.578 205.621 1.00 53.32  ? 6   C     E N1     1 
ATOM   540  C C2     . C     C 2 6   ? 243.588 263.225 204.845 1.00 54.48  ? 6   C     E C2     1 
ATOM   541  O O2     . C     C 2 6   ? 242.435 262.774 204.832 1.00 60.13  ? 6   C     E O2     1 
ATOM   542  N N3     . C     C 2 6   ? 243.932 264.319 204.130 1.00 49.80  ? 6   C     E N3     1 
ATOM   543  C C4     . C     C 2 6   ? 245.185 264.768 204.174 1.00 55.32  ? 6   C     E C4     1 
ATOM   544  N N4     . C     C 2 6   ? 245.482 265.850 203.454 1.00 60.04  ? 6   C     E N4     1 
ATOM   545  C C5     . C     C 2 6   ? 246.188 264.129 204.958 1.00 53.21  ? 6   C     E C5     1 
ATOM   546  C C6     . C     C 2 6   ? 245.831 263.047 205.658 1.00 51.54  ? 6   C     E C6     1 
ATOM   547  P P      . U     C 2 7   ? 246.549 257.737 204.293 1.00 68.84  ? 7   U     E P      1 
ATOM   548  O OP1    . U     C 2 7   ? 247.952 258.203 204.414 1.00 61.65  ? 7   U     E OP1    1 
ATOM   549  O OP2    . U     C 2 7   ? 245.753 258.128 203.103 1.00 65.76  ? 7   U     E OP2    1 
ATOM   550  O "O5'"  . U     C 2 7   ? 246.552 256.149 204.392 1.00 65.44  ? 7   U     E "O5'"  1 
ATOM   551  C "C5'"  . U     C 2 7   ? 247.301 255.482 205.400 1.00 60.82  ? 7   U     E "C5'"  1 
ATOM   552  C "C4'"  . U     C 2 7   ? 247.802 254.142 204.925 1.00 66.81  ? 7   U     E "C4'"  1 
ATOM   553  O "O4'"  . U     C 2 7   ? 246.725 253.169 205.003 1.00 70.19  ? 7   U     E "O4'"  1 
ATOM   554  C "C3'"  . U     C 2 7   ? 248.302 254.110 203.482 1.00 67.99  ? 7   U     E "C3'"  1 
ATOM   555  O "O3'"  . U     C 2 7   ? 249.386 253.192 203.375 1.00 68.42  ? 7   U     E "O3'"  1 
ATOM   556  C "C2'"  . U     C 2 7   ? 247.100 253.559 202.723 1.00 70.79  ? 7   U     E "C2'"  1 
ATOM   557  O "O2'"  . U     C 2 7   ? 247.418 252.928 201.501 1.00 74.31  ? 7   U     E "O2'"  1 
ATOM   558  C "C1'"  . U     C 2 7   ? 246.528 252.574 203.736 1.00 67.71  ? 7   U     E "C1'"  1 
ATOM   559  N N1     . U     C 2 7   ? 245.094 252.305 203.569 1.00 64.41  ? 7   U     E N1     1 
ATOM   560  C C2     . U     C 2 7   ? 244.217 253.357 203.726 1.00 71.00  ? 7   U     E C2     1 
ATOM   561  O O2     . U     C 2 7   ? 244.581 254.486 203.995 1.00 74.72  ? 7   U     E O2     1 
ATOM   562  N N3     . U     C 2 7   ? 242.894 253.040 203.555 1.00 69.37  ? 7   U     E N3     1 
ATOM   563  C C4     . U     C 2 7   ? 242.372 251.803 203.251 1.00 70.24  ? 7   U     E C4     1 
ATOM   564  O O4     . U     C 2 7   ? 241.154 251.676 203.129 1.00 77.58  ? 7   U     E O4     1 
ATOM   565  C C5     . U     C 2 7   ? 243.343 250.765 203.104 1.00 64.58  ? 7   U     E C5     1 
ATOM   566  C C6     . U     C 2 7   ? 244.639 251.045 203.264 1.00 59.83  ? 7   U     E C6     1 
ATOM   567  P P      . C     C 2 8   ? 250.869 253.725 203.062 1.00 75.83  ? 8   C     E P      1 
ATOM   568  O OP1    . C     C 2 8   ? 250.925 255.172 203.386 1.00 63.30  ? 8   C     E OP1    1 
ATOM   569  O OP2    . C     C 2 8   ? 251.247 253.266 201.704 1.00 83.28  ? 8   C     E OP2    1 
ATOM   570  O "O5'"  . C     C 2 8   ? 251.775 252.955 204.119 1.00 70.14  ? 8   C     E "O5'"  1 
ATOM   571  C "C5'"  . C     C 2 8   ? 251.903 253.434 205.447 1.00 66.44  ? 8   C     E "C5'"  1 
ATOM   572  C "C4'"  . C     C 2 8   ? 251.969 252.304 206.441 1.00 71.15  ? 8   C     E "C4'"  1 
ATOM   573  O "O4'"  . C     C 2 8   ? 250.676 251.658 206.556 1.00 71.55  ? 8   C     E "O4'"  1 
ATOM   574  C "C3'"  . C     C 2 8   ? 252.911 251.164 206.099 1.00 74.44  ? 8   C     E "C3'"  1 
ATOM   575  O "O3'"  . C     C 2 8   ? 254.263 251.465 206.383 1.00 75.52  ? 8   C     E "O3'"  1 
ATOM   576  C "C2'"  . C     C 2 8   ? 252.355 250.018 206.932 1.00 77.14  ? 8   C     E "C2'"  1 
ATOM   577  O "O2'"  . C     C 2 8   ? 252.759 250.142 208.287 1.00 80.90  ? 8   C     E "O2'"  1 
ATOM   578  C "C1'"  . C     C 2 8   ? 250.852 250.288 206.853 1.00 71.09  ? 8   C     E "C1'"  1 
ATOM   579  N N1     . C     C 2 8   ? 250.192 249.476 205.807 1.00 65.94  ? 8   C     E N1     1 
ATOM   580  C C2     . C     C 2 8   ? 250.000 248.118 206.058 1.00 67.93  ? 8   C     E C2     1 
ATOM   581  O O2     . C     C 2 8   ? 250.395 247.653 207.136 1.00 70.82  ? 8   C     E O2     1 
ATOM   582  N N3     . C     C 2 8   ? 249.399 247.346 205.128 1.00 65.18  ? 8   C     E N3     1 
ATOM   583  C C4     . C     C 2 8   ? 248.992 247.890 203.984 1.00 65.72  ? 8   C     E C4     1 
ATOM   584  N N4     . C     C 2 8   ? 248.402 247.092 203.094 1.00 68.65  ? 8   C     E N4     1 
ATOM   585  C C5     . C     C 2 8   ? 249.169 249.274 203.701 1.00 64.19  ? 8   C     E C5     1 
ATOM   586  C C6     . C     C 2 8   ? 249.770 250.025 204.632 1.00 64.81  ? 8   C     E C6     1 
ATOM   587  P P      . U     C 2 9   ? 255.410 251.073 205.332 1.00 76.91  ? 9   U     E P      1 
ATOM   588  O OP1    . U     C 2 9   ? 255.204 251.894 204.112 1.00 73.32  ? 9   U     E OP1    1 
ATOM   589  O OP2    . U     C 2 9   ? 255.456 249.593 205.230 1.00 83.16  ? 9   U     E OP2    1 
ATOM   590  O "O5'"  . U     C 2 9   ? 256.753 251.561 206.032 1.00 72.37  ? 9   U     E "O5'"  1 
ATOM   591  C "C5'"  . U     C 2 9   ? 257.190 252.909 205.909 1.00 70.41  ? 9   U     E "C5'"  1 
ATOM   592  C "C4'"  . U     C 2 9   ? 257.405 253.553 207.255 1.00 73.27  ? 9   U     E "C4'"  1 
ATOM   593  O "O4'"  . U     C 2 9   ? 258.353 254.643 207.108 1.00 73.93  ? 9   U     E "O4'"  1 
ATOM   594  C "C3'"  . U     C 2 9   ? 256.157 254.159 207.891 1.00 74.05  ? 9   U     E "C3'"  1 
ATOM   595  O "O3'"  . U     C 2 9   ? 256.258 254.069 209.311 1.00 77.57  ? 9   U     E "O3'"  1 
ATOM   596  C "C2'"  . U     C 2 9   ? 256.250 255.620 207.471 1.00 73.90  ? 9   U     E "C2'"  1 
ATOM   597  O "O2'"  . U     C 2 9   ? 255.549 256.515 208.308 1.00 77.74  ? 9   U     E "O2'"  1 
ATOM   598  C "C1'"  . U     C 2 9   ? 257.756 255.856 207.524 1.00 72.18  ? 9   U     E "C1'"  1 
ATOM   599  N N1     . U     C 2 9   ? 258.224 256.919 206.625 1.00 69.46  ? 9   U     E N1     1 
ATOM   600  C C2     . U     C 2 9   ? 258.183 256.667 205.271 1.00 69.15  ? 9   U     E C2     1 
ATOM   601  O O2     . U     C 2 9   ? 257.777 255.617 204.808 1.00 71.37  ? 9   U     E O2     1 
ATOM   602  N N3     . U     C 2 9   ? 258.633 257.691 204.477 1.00 65.48  ? 9   U     E N3     1 
ATOM   603  C C4     . U     C 2 9   ? 259.109 258.914 204.896 1.00 67.56  ? 9   U     E C4     1 
ATOM   604  O O4     . U     C 2 9   ? 259.479 259.735 204.059 1.00 70.26  ? 9   U     E O4     1 
ATOM   605  C C5     . U     C 2 9   ? 259.122 259.097 206.313 1.00 66.97  ? 9   U     E C5     1 
ATOM   606  C C6     . U     C 2 9   ? 258.691 258.116 207.110 1.00 67.88  ? 9   U     E C6     1 
ATOM   607  P P      . C     C 2 10  ? 255.428 252.954 210.115 1.00 83.14  ? 10  C     E P      1 
ATOM   608  O OP1    . C     C 2 10  ? 254.389 252.409 209.207 1.00 79.86  ? 10  C     E OP1    1 
ATOM   609  O OP2    . C     C 2 10  ? 255.032 253.526 211.425 1.00 86.52  ? 10  C     E OP2    1 
ATOM   610  O "O5'"  . C     C 2 10  ? 256.494 251.803 210.382 1.00 76.99  ? 10  C     E "O5'"  1 
ATOM   611  C "C5'"  . C     C 2 10  ? 256.631 250.715 209.476 1.00 75.86  ? 10  C     E "C5'"  1 
ATOM   612  C "C4'"  . C     C 2 10  ? 257.914 249.957 209.705 1.00 80.16  ? 10  C     E "C4'"  1 
ATOM   613  O "O4'"  . C     C 2 10  ? 259.032 250.754 209.229 1.00 78.32  ? 10  C     E "O4'"  1 
ATOM   614  C "C3'"  . C     C 2 10  ? 258.218 249.622 211.163 1.00 84.71  ? 10  C     E "C3'"  1 
ATOM   615  O "O3'"  . C     C 2 10  ? 258.885 248.364 211.232 1.00 91.56  ? 10  C     E "O3'"  1 
ATOM   616  C "C2'"  . C     C 2 10  ? 259.180 250.732 211.570 1.00 80.56  ? 10  C     E "C2'"  1 
ATOM   617  O "O2'"  . C     C 2 10  ? 260.033 250.402 212.644 1.00 81.66  ? 10  C     E "O2'"  1 
ATOM   618  C "C1'"  . C     C 2 10  ? 259.959 250.953 210.277 1.00 76.79  ? 10  C     E "C1'"  1 
ATOM   619  N N1     . C     C 2 10  ? 260.520 252.304 210.139 1.00 71.40  ? 10  C     E N1     1 
ATOM   620  C C2     . C     C 2 10  ? 261.906 252.463 210.119 1.00 70.32  ? 10  C     E C2     1 
ATOM   621  O O2     . C     C 2 10  ? 262.623 251.458 210.222 1.00 78.48  ? 10  C     E O2     1 
ATOM   622  N N3     . C     C 2 10  ? 262.431 253.702 209.992 1.00 63.85  ? 10  C     E N3     1 
ATOM   623  C C4     . C     C 2 10  ? 261.623 254.756 209.884 1.00 63.67  ? 10  C     E C4     1 
ATOM   624  N N4     . C     C 2 10  ? 262.180 255.961 209.760 1.00 65.23  ? 10  C     E N4     1 
ATOM   625  C C5     . C     C 2 10  ? 260.206 254.624 209.899 1.00 68.55  ? 10  C     E C5     1 
ATOM   626  C C6     . C     C 2 10  ? 259.704 253.391 210.027 1.00 73.67  ? 10  C     E C6     1 
ATOM   627  P P      . U     C 2 11  ? 258.034 247.003 211.237 1.00 97.78  ? 11  U     E P      1 
ATOM   628  O OP1    . U     C 2 11  ? 258.978 245.870 211.067 1.00 93.87  ? 11  U     E OP1    1 
ATOM   629  O OP2    . U     C 2 11  ? 256.902 247.162 210.291 1.00 97.64  ? 11  U     E OP2    1 
ATOM   630  O "O5'"  . U     C 2 11  ? 257.434 246.932 212.709 1.00 102.44 ? 11  U     E "O5'"  1 
ATOM   631  C "C5'"  . U     C 2 11  ? 258.140 246.277 213.756 1.00 111.07 ? 11  U     E "C5'"  1 
ATOM   632  C "C4'"  . U     C 2 11  ? 257.210 245.860 214.868 1.00 117.39 ? 11  U     E "C4'"  1 
ATOM   633  O "O4'"  . U     C 2 11  ? 256.871 247.027 215.664 1.00 114.02 ? 11  U     E "O4'"  1 
ATOM   634  C "C3'"  . U     C 2 11  ? 255.887 245.261 214.403 1.00 120.49 ? 11  U     E "C3'"  1 
ATOM   635  O "O3'"  . U     C 2 11  ? 255.458 244.263 215.325 1.00 123.47 ? 11  U     E "O3'"  1 
ATOM   636  C "C2'"  . U     C 2 11  ? 254.939 246.452 214.457 1.00 122.37 ? 11  U     E "C2'"  1 
ATOM   637  O "O2'"  . U     C 2 11  ? 253.578 246.111 214.609 1.00 129.80 ? 11  U     E "O2'"  1 
ATOM   638  C "C1'"  . U     C 2 11  ? 255.470 247.217 215.666 1.00 119.21 ? 11  U     E "C1'"  1 
ATOM   639  N N1     . U     C 2 11  ? 255.216 248.661 215.598 1.00 123.03 ? 11  U     E N1     1 
ATOM   640  C C2     . U     C 2 11  ? 254.383 249.228 216.538 1.00 131.21 ? 11  U     E C2     1 
ATOM   641  O O2     . U     C 2 11  ? 253.849 248.584 217.424 1.00 137.00 ? 11  U     E O2     1 
ATOM   642  N N3     . U     C 2 11  ? 254.199 250.581 216.397 1.00 133.15 ? 11  U     E N3     1 
ATOM   643  C C4     . U     C 2 11  ? 254.753 251.401 215.435 1.00 132.01 ? 11  U     E C4     1 
ATOM   644  O O4     . U     C 2 11  ? 254.493 252.604 215.440 1.00 135.00 ? 11  U     E O4     1 
ATOM   645  C C5     . U     C 2 11  ? 255.603 250.734 214.500 1.00 121.16 ? 11  U     E C5     1 
ATOM   646  C C6     . U     C 2 11  ? 255.798 249.419 214.613 1.00 119.22 ? 11  U     E C6     1 
ATOM   647  P P      . C     C 2 12  ? 255.087 242.798 214.787 1.00 134.07 ? 12  C     E P      1 
ATOM   648  O OP1    . C     C 2 12  ? 253.623 242.759 214.545 1.00 137.67 ? 12  C     E OP1    1 
ATOM   649  O OP2    . C     C 2 12  ? 255.715 241.794 215.683 1.00 142.11 ? 12  C     E OP2    1 
ATOM   650  O "O5'"  . C     C 2 12  ? 255.816 242.725 213.373 1.00 127.65 ? 12  C     E "O5'"  1 
ATOM   651  C "C5'"  . C     C 2 12  ? 256.238 241.483 212.834 1.00 134.26 ? 12  C     E "C5'"  1 
ATOM   652  C "C4'"  . C     C 2 12  ? 257.722 241.472 212.577 1.00 137.91 ? 12  C     E "C4'"  1 
ATOM   653  O "O4'"  . C     C 2 12  ? 258.424 241.893 213.775 1.00 140.53 ? 12  C     E "O4'"  1 
ATOM   654  C "C3'"  . C     C 2 12  ? 258.324 240.114 212.252 1.00 148.35 ? 12  C     E "C3'"  1 
ATOM   655  O "O3'"  . C     C 2 12  ? 258.165 239.744 210.895 1.00 160.09 ? 12  C     E "O3'"  1 
ATOM   656  C "C2'"  . C     C 2 12  ? 259.775 240.282 212.677 1.00 149.08 ? 12  C     E "C2'"  1 
ATOM   657  O "O2'"  . C     C 2 12  ? 260.501 241.015 211.702 1.00 152.03 ? 12  C     E "O2'"  1 
ATOM   658  C "C1'"  . C     C 2 12  ? 259.620 241.156 213.919 1.00 146.62 ? 12  C     E "C1'"  1 
ATOM   659  N N1     . C     C 2 12  ? 259.518 240.348 215.154 1.00 148.18 ? 12  C     E N1     1 
ATOM   660  C C2     . C     C 2 12  ? 260.626 239.613 215.574 1.00 150.32 ? 12  C     E C2     1 
ATOM   661  O O2     . C     C 2 12  ? 261.662 239.653 214.895 1.00 152.18 ? 12  C     E O2     1 
ATOM   662  N N3     . C     C 2 12  ? 260.538 238.873 216.702 1.00 153.10 ? 12  C     E N3     1 
ATOM   663  C C4     . C     C 2 12  ? 259.403 238.858 217.401 1.00 153.84 ? 12  C     E C4     1 
ATOM   664  N N4     . C     C 2 12  ? 259.364 238.116 218.509 1.00 160.83 ? 12  C     E N4     1 
ATOM   665  C C5     . C     C 2 12  ? 258.259 239.603 216.998 1.00 147.96 ? 12  C     E C5     1 
ATOM   666  C C6     . C     C 2 12  ? 258.360 240.327 215.878 1.00 148.09 ? 12  C     E C6     1 
ATOM   667  P P      . U     C 2 13  ? 258.068 238.190 210.499 1.00 182.27 ? 13  U     E P      1 
ATOM   668  O OP1    . U     C 2 13  ? 259.439 237.620 210.529 1.00 176.31 ? 13  U     E OP1    1 
ATOM   669  O OP2    . U     C 2 13  ? 257.249 238.076 209.266 1.00 178.60 ? 13  U     E OP2    1 
ATOM   670  O "O5'"  . U     C 2 13  ? 257.245 237.548 211.702 1.00 165.77 ? 13  U     E "O5'"  1 
ATOM   671  C "C5'"  . U     C 2 13  ? 257.247 236.147 211.926 1.00 160.20 ? 13  U     E "C5'"  1 
ATOM   672  C "C4'"  . U     C 2 13  ? 258.131 235.784 213.090 1.00 151.53 ? 13  U     E "C4'"  1 
ATOM   673  O "O4'"  . U     C 2 13  ? 258.154 236.876 214.047 1.00 154.49 ? 13  U     E "O4'"  1 
ATOM   674  C "C3'"  . U     C 2 13  ? 257.691 234.582 213.911 1.00 146.76 ? 13  U     E "C3'"  1 
ATOM   675  O "O3'"  . U     C 2 13  ? 258.060 233.345 213.330 1.00 142.64 ? 13  U     E "O3'"  1 
ATOM   676  C "C2'"  . U     C 2 13  ? 258.344 234.848 215.259 1.00 149.12 ? 13  U     E "C2'"  1 
ATOM   677  O "O2'"  . U     C 2 13  ? 259.728 234.537 215.216 1.00 144.43 ? 13  U     E "O2'"  1 
ATOM   678  C "C1'"  . U     C 2 13  ? 258.197 236.364 215.362 1.00 155.45 ? 13  U     E "C1'"  1 
ATOM   679  N N1     . U     C 2 13  ? 256.941 236.748 216.044 1.00 166.13 ? 13  U     E N1     1 
ATOM   680  C C2     . U     C 2 13  ? 256.881 236.626 217.417 1.00 167.62 ? 13  U     E C2     1 
ATOM   681  O O2     . U     C 2 13  ? 257.815 236.218 218.085 1.00 165.89 ? 13  U     E O2     1 
ATOM   682  N N3     . U     C 2 13  ? 255.686 237.000 217.981 1.00 175.01 ? 13  U     E N3     1 
ATOM   683  C C4     . U     C 2 13  ? 254.570 237.474 217.322 1.00 176.48 ? 13  U     E C4     1 
ATOM   684  O O4     . U     C 2 13  ? 253.565 237.770 217.970 1.00 182.18 ? 13  U     E O4     1 
ATOM   685  C C5     . U     C 2 13  ? 254.712 237.570 215.902 1.00 170.42 ? 13  U     E C5     1 
ATOM   686  C C6     . U     C 2 13  ? 255.864 237.212 215.326 1.00 167.15 ? 13  U     E C6     1 
ATOM   687  P P      . C     C 2 14  ? 257.625 231.970 214.034 1.00 141.73 ? 14  C     E P      1 
ATOM   688  O OP1    . C     C 2 14  ? 257.742 230.886 213.027 1.00 133.38 ? 14  C     E OP1    1 
ATOM   689  O OP2    . C     C 2 14  ? 256.332 232.187 214.730 1.00 143.30 ? 14  C     E OP2    1 
ATOM   690  O "O5'"  . C     C 2 14  ? 258.748 231.736 215.137 1.00 134.74 ? 14  C     E "O5'"  1 
ATOM   691  C "C5'"  . C     C 2 14  ? 260.007 231.178 214.781 1.00 133.35 ? 14  C     E "C5'"  1 
ATOM   692  C "C4'"  . C     C 2 14  ? 260.668 230.500 215.954 1.00 133.33 ? 14  C     E "C4'"  1 
ATOM   693  O "O4'"  . C     C 2 14  ? 261.449 231.475 216.697 1.00 147.15 ? 14  C     E "O4'"  1 
ATOM   694  C "C3'"  . C     C 2 14  ? 259.713 229.862 216.959 1.00 131.77 ? 14  C     E "C3'"  1 
ATOM   695  O "O3'"  . C     C 2 14  ? 260.304 228.676 217.487 1.00 131.04 ? 14  C     E "O3'"  1 
ATOM   696  C "C2'"  . C     C 2 14  ? 259.622 230.920 218.054 1.00 144.15 ? 14  C     E "C2'"  1 
ATOM   697  O "O2'"  . C     C 2 14  ? 259.258 230.423 219.324 1.00 152.92 ? 14  C     E "O2'"  1 
ATOM   698  C "C1'"  . C     C 2 14  ? 261.040 231.480 218.050 1.00 153.54 ? 14  C     E "C1'"  1 
ATOM   699  N N1     . C     C 2 14  ? 261.146 232.854 218.560 1.00 164.29 ? 14  C     E N1     1 
ATOM   700  C C2     . C     C 2 14  ? 262.043 233.113 219.599 1.00 171.41 ? 14  C     E C2     1 
ATOM   701  O O2     . C     C 2 14  ? 262.720 232.179 220.054 1.00 172.23 ? 14  C     E O2     1 
ATOM   702  N N3     . C     C 2 14  ? 262.153 234.373 220.080 1.00 174.08 ? 14  C     E N3     1 
ATOM   703  C C4     . C     C 2 14  ? 261.406 235.350 219.561 1.00 171.86 ? 14  C     E C4     1 
ATOM   704  N N4     . C     C 2 14  ? 261.546 236.578 220.066 1.00 174.27 ? 14  C     E N4     1 
ATOM   705  C C5     . C     C 2 14  ? 260.484 235.111 218.502 1.00 166.07 ? 14  C     E C5     1 
ATOM   706  C C6     . C     C 2 14  ? 260.385 233.860 218.036 1.00 160.65 ? 14  C     E C6     1 
ATOM   707  P P      . U     C 2 15  ? 259.969 227.254 216.823 1.00 115.41 ? 15  U     E P      1 
ATOM   708  O OP1    . U     C 2 15  ? 258.574 226.900 217.186 1.00 118.03 ? 15  U     E OP1    1 
ATOM   709  O OP2    . U     C 2 15  ? 261.073 226.310 217.123 1.00 109.03 ? 15  U     E OP2    1 
ATOM   710  O "O5'"  . U     C 2 15  ? 260.000 227.552 215.262 1.00 99.95  ? 15  U     E "O5'"  1 
ATOM   711  C "C5'"  . U     C 2 15  ? 259.699 226.535 214.323 1.00 82.08  ? 15  U     E "C5'"  1 
ATOM   712  C "C4'"  . U     C 2 15  ? 259.447 227.110 212.954 1.00 78.26  ? 15  U     E "C4'"  1 
ATOM   713  O "O4'"  . U     C 2 15  ? 260.692 227.588 212.390 1.00 76.29  ? 15  U     E "O4'"  1 
ATOM   714  C "C3'"  . U     C 2 15  ? 258.913 226.133 211.918 1.00 69.46  ? 15  U     E "C3'"  1 
ATOM   715  O "O3'"  . U     C 2 15  ? 257.509 225.968 212.006 1.00 72.46  ? 15  U     E "O3'"  1 
ATOM   716  C "C2'"  . U     C 2 15  ? 259.365 226.748 210.599 1.00 67.98  ? 15  U     E "C2'"  1 
ATOM   717  O "O2'"  . U     C 2 15  ? 258.468 227.770 210.193 1.00 70.49  ? 15  U     E "O2'"  1 
ATOM   718  C "C1'"  . U     C 2 15  ? 260.692 227.401 210.993 1.00 69.02  ? 15  U     E "C1'"  1 
ATOM   719  N N1     . U     C 2 15  ? 261.892 226.618 210.605 1.00 61.63  ? 15  U     E N1     1 
ATOM   720  C C2     . U     C 2 15  ? 261.917 225.237 210.692 1.00 63.74  ? 15  U     E C2     1 
ATOM   721  O O2     . U     C 2 15  ? 260.994 224.562 211.103 1.00 68.13  ? 15  U     E O2     1 
ATOM   722  N N3     . U     C 2 15  ? 263.096 224.654 210.296 1.00 57.71  ? 15  U     E N3     1 
ATOM   723  C C4     . U     C 2 15  ? 264.223 225.285 209.817 1.00 55.82  ? 15  U     E C4     1 
ATOM   724  O O4     . U     C 2 15  ? 265.205 224.617 209.494 1.00 55.06  ? 15  U     E O4     1 
ATOM   725  C C5     . U     C 2 15  ? 264.118 226.706 209.744 1.00 58.02  ? 15  U     E C5     1 
ATOM   726  C C6     . U     C 2 15  ? 262.986 227.299 210.128 1.00 59.50  ? 15  U     E C6     1 
ATOM   727  P P      . C     C 2 16  ? 256.847 224.511 211.872 1.00 77.95  ? 16  C     E P      1 
ATOM   728  O OP1    . C     C 2 16  ? 255.399 224.648 212.157 1.00 65.89  ? 16  C     E OP1    1 
ATOM   729  O OP2    . C     C 2 16  ? 257.658 223.548 212.658 1.00 79.55  ? 16  C     E OP2    1 
ATOM   730  O "O5'"  . C     C 2 16  ? 257.001 224.164 210.326 1.00 64.63  ? 16  C     E "O5'"  1 
ATOM   731  C "C5'"  . C     C 2 16  ? 256.504 225.051 209.332 1.00 57.92  ? 16  C     E "C5'"  1 
ATOM   732  C "C4'"  . C     C 2 16  ? 256.314 224.359 208.007 1.00 60.56  ? 16  C     E "C4'"  1 
ATOM   733  O "O4'"  . C     C 2 16  ? 257.607 223.936 207.495 1.00 65.66  ? 16  C     E "O4'"  1 
ATOM   734  C "C3'"  . C     C 2 16  ? 255.441 223.107 208.046 1.00 60.08  ? 16  C     E "C3'"  1 
ATOM   735  O "O3'"  . C     C 2 16  ? 254.701 223.017 206.831 1.00 65.96  ? 16  C     E "O3'"  1 
ATOM   736  C "C2'"  . C     C 2 16  ? 256.469 221.982 208.108 1.00 61.00  ? 16  C     E "C2'"  1 
ATOM   737  O "O2'"  . C     C 2 16  ? 256.008 220.739 207.627 1.00 61.15  ? 16  C     E "O2'"  1 
ATOM   738  C "C1'"  . C     C 2 16  ? 257.589 222.545 207.241 1.00 60.10  ? 16  C     E "C1'"  1 
ATOM   739  N N1     . C     C 2 16  ? 258.922 222.006 207.544 1.00 56.22  ? 16  C     E N1     1 
ATOM   740  C C2     . C     C 2 16  ? 259.560 221.219 206.585 1.00 54.51  ? 16  C     E C2     1 
ATOM   741  O O2     . C     C 2 16  ? 258.974 220.996 205.517 1.00 59.32  ? 16  C     E O2     1 
ATOM   742  N N3     . C     C 2 16  ? 260.790 220.722 206.843 1.00 47.81  ? 16  C     E N3     1 
ATOM   743  C C4     . C     C 2 16  ? 261.382 220.989 208.006 1.00 51.66  ? 16  C     E C4     1 
ATOM   744  N N4     . C     C 2 16  ? 262.593 220.478 208.221 1.00 52.27  ? 16  C     E N4     1 
ATOM   745  C C5     . C     C 2 16  ? 260.758 221.793 209.002 1.00 51.37  ? 16  C     E C5     1 
ATOM   746  C C6     . C     C 2 16  ? 259.541 222.277 208.732 1.00 55.26  ? 16  C     E C6     1 
ATOM   747  P P      . U     C 2 17  ? 253.153 223.444 206.801 1.00 73.65  ? 17  U     E P      1 
ATOM   748  O OP1    . U     C 2 17  ? 252.872 224.078 205.490 1.00 64.55  ? 17  U     E OP1    1 
ATOM   749  O OP2    . U     C 2 17  ? 252.857 224.186 208.051 1.00 72.09  ? 17  U     E OP2    1 
ATOM   750  O "O5'"  . U     C 2 17  ? 252.383 222.054 206.859 1.00 65.66  ? 17  U     E "O5'"  1 
ATOM   751  C "C5'"  . U     C 2 17  ? 253.086 220.862 207.181 1.00 65.40  ? 17  U     E "C5'"  1 
ATOM   752  C "C4'"  . U     C 2 17  ? 252.154 219.715 207.475 1.00 61.74  ? 17  U     E "C4'"  1 
ATOM   753  O "O4'"  . U     C 2 17  ? 251.165 219.629 206.415 1.00 61.94  ? 17  U     E "O4'"  1 
ATOM   754  C "C3'"  . U     C 2 17  ? 252.831 218.350 207.541 1.00 66.04  ? 17  U     E "C3'"  1 
ATOM   755  O "O3'"  . U     C 2 17  ? 252.162 217.526 208.494 1.00 57.82  ? 17  U     E "O3'"  1 
ATOM   756  C "C2'"  . U     C 2 17  ? 252.619 217.803 206.134 1.00 70.91  ? 17  U     E "C2'"  1 
ATOM   757  O "O2'"  . U     C 2 17  ? 252.648 216.394 206.041 1.00 76.23  ? 17  U     E "O2'"  1 
ATOM   758  C "C1'"  . U     C 2 17  ? 251.243 218.365 205.784 1.00 66.27  ? 17  U     E "C1'"  1 
ATOM   759  N N1     . U     C 2 17  ? 251.035 218.568 204.343 1.00 64.84  ? 17  U     E N1     1 
ATOM   760  C C2     . U     C 2 17  ? 250.493 217.533 203.613 1.00 71.78  ? 17  U     E C2     1 
ATOM   761  O O2     . U     C 2 17  ? 250.190 216.463 204.111 1.00 79.17  ? 17  U     E O2     1 
ATOM   762  N N3     . U     C 2 17  ? 250.328 217.793 202.276 1.00 70.32  ? 17  U     E N3     1 
ATOM   763  C C4     . U     C 2 17  ? 250.637 218.961 201.611 1.00 63.17  ? 17  U     E C4     1 
ATOM   764  O O4     . U     C 2 17  ? 250.427 219.043 200.402 1.00 61.86  ? 17  U     E O4     1 
ATOM   765  C C5     . U     C 2 17  ? 251.187 219.987 202.438 1.00 61.72  ? 17  U     E C5     1 
ATOM   766  C C6     . U     C 2 17  ? 251.361 219.759 203.742 1.00 63.97  ? 17  U     E C6     1 
ATOM   767  P P      . C     C 2 18  ? 253.025 217.530 209.792 1.00 51.84  ? 18  C     E P      1 
ATOM   768  O OP2    . C     C 2 18  ? 254.014 218.616 209.421 1.00 51.84  ? 18  C     E OP2    1 
ATOM   769  O "O5'"  . C     C 2 18  ? 253.772 216.130 209.655 1.00 51.84  ? 18  C     E "O5'"  1 
ATOM   770  C "C5'"  . C     C 2 18  ? 254.698 215.692 210.639 1.00 51.84  ? 18  C     E "C5'"  1 
ATOM   771  C "C4'"  . C     C 2 18  ? 256.035 215.377 210.020 1.00 51.84  ? 18  C     E "C4'"  1 
ATOM   772  O "O4'"  . C     C 2 18  ? 256.587 216.582 209.430 1.00 51.84  ? 18  C     E "O4'"  1 
ATOM   773  C "C3'"  . C     C 2 18  ? 257.131 214.889 210.959 1.00 51.84  ? 18  C     E "C3'"  1 
ATOM   774  O "O3'"  . C     C 2 18  ? 257.041 213.504 211.250 1.00 51.84  ? 18  C     E "O3'"  1 
ATOM   775  C "C2'"  . C     C 2 18  ? 258.397 215.259 210.203 1.00 51.84  ? 18  C     E "C2'"  1 
ATOM   776  O "O2'"  . C     C 2 18  ? 258.605 214.343 209.140 1.00 51.84  ? 18  C     E "O2'"  1 
ATOM   777  C "C1'"  . C     C 2 18  ? 257.989 216.597 209.590 1.00 51.84  ? 18  C     E "C1'"  1 
ATOM   778  N N1     . C     C 2 18  ? 258.377 217.755 210.428 1.00 51.84  ? 18  C     E N1     1 
ATOM   779  C C2     . C     C 2 18  ? 257.651 218.944 210.310 1.00 51.84  ? 18  C     E C2     1 
ATOM   780  O O2     . C     C 2 18  ? 256.703 218.991 209.512 1.00 51.84  ? 18  C     E O2     1 
ATOM   781  N N3     . C     C 2 18  ? 258.006 220.008 211.069 1.00 51.84  ? 18  C     E N3     1 
ATOM   782  C C4     . C     C 2 18  ? 259.038 219.923 211.917 1.00 51.84  ? 18  C     E C4     1 
ATOM   783  N N4     . C     C 2 18  ? 259.339 220.996 212.632 1.00 51.84  ? 18  C     E N4     1 
ATOM   784  C C5     . C     C 2 18  ? 259.789 218.724 212.047 1.00 51.84  ? 18  C     E C5     1 
ATOM   785  C C6     . C     C 2 18  ? 259.429 217.675 211.291 1.00 51.84  ? 18  C     E C6     1 
ATOM   786  O OP3    . U     D 2 1   ? 272.991 219.984 200.998 1.00 58.12  ? 1   U     F OP3    1 
ATOM   787  P P      . U     D 2 1   ? 273.467 218.605 200.768 1.00 60.12  ? 1   U     F P      1 
ATOM   788  O OP1    . U     D 2 1   ? 272.382 217.840 200.108 1.00 58.03  ? 1   U     F OP1    1 
ATOM   789  O OP2    . U     D 2 1   ? 274.025 218.100 202.044 1.00 60.70  ? 1   U     F OP2    1 
ATOM   790  O "O5'"  . U     D 2 1   ? 274.673 218.681 199.733 1.00 59.73  ? 1   U     F "O5'"  1 
ATOM   791  C "C5'"  . U     D 2 1   ? 275.353 219.908 199.497 1.00 59.47  ? 1   U     F "C5'"  1 
ATOM   792  C "C4'"  . U     D 2 1   ? 276.585 219.710 198.650 1.00 59.89  ? 1   U     F "C4'"  1 
ATOM   793  O "O4'"  . U     D 2 1   ? 277.443 218.724 199.286 1.00 60.44  ? 1   U     F "O4'"  1 
ATOM   794  C "C3'"  . U     D 2 1   ? 276.328 219.198 197.234 1.00 58.70  ? 1   U     F "C3'"  1 
ATOM   795  O "O3'"  . U     D 2 1   ? 277.280 219.764 196.335 1.00 60.06  ? 1   U     F "O3'"  1 
ATOM   796  C "C2'"  . U     D 2 1   ? 276.571 217.700 197.366 1.00 59.01  ? 1   U     F "C2'"  1 
ATOM   797  O "O2'"  . U     D 2 1   ? 276.928 217.054 196.162 1.00 60.51  ? 1   U     F "O2'"  1 
ATOM   798  C "C1'"  . U     D 2 1   ? 277.705 217.667 198.385 1.00 58.70  ? 1   U     F "C1'"  1 
ATOM   799  N N1     . U     D 2 1   ? 277.794 216.414 199.149 1.00 57.59  ? 1   U     F N1     1 
ATOM   800  C C2     . U     D 2 1   ? 278.985 215.714 199.122 1.00 57.29  ? 1   U     F C2     1 
ATOM   801  O O2     . U     D 2 1   ? 279.966 216.084 198.503 1.00 57.19  ? 1   U     F O2     1 
ATOM   802  N N3     . U     D 2 1   ? 278.990 214.555 199.853 1.00 57.36  ? 1   U     F N3     1 
ATOM   803  C C4     . U     D 2 1   ? 277.952 214.033 200.591 1.00 56.59  ? 1   U     F C4     1 
ATOM   804  O O4     . U     D 2 1   ? 278.118 212.974 201.196 1.00 56.44  ? 1   U     F O4     1 
ATOM   805  C C5     . U     D 2 1   ? 276.753 214.809 200.572 1.00 57.38  ? 1   U     F C5     1 
ATOM   806  C C6     . U     D 2 1   ? 276.720 215.943 199.866 1.00 58.25  ? 1   U     F C6     1 
ATOM   807  H "H5'"  . U     D 2 1   ? 275.613 220.292 200.348 1.00 59.48  ? 1   U     F "H5'"  1 
ATOM   808  H "H5''" . U     D 2 1   ? 274.751 220.520 199.043 1.00 59.34  ? 1   U     F "H5''" 1 
ATOM   809  H "H4'"  . U     D 2 1   ? 277.064 220.551 198.594 1.00 59.77  ? 1   U     F "H4'"  1 
ATOM   810  H "H3'"  . U     D 2 1   ? 275.419 219.382 196.949 1.00 58.91  ? 1   U     F "H3'"  1 
ATOM   811  H "H2'"  . U     D 2 1   ? 275.779 217.279 197.735 1.00 58.92  ? 1   U     F "H2'"  1 
ATOM   812  H "HO2'" . U     D 2 1   ? 276.339 217.206 195.583 1.00 59.89  ? 1   U     F "HO2'" 1 
ATOM   813  H "H1'"  . U     D 2 1   ? 278.545 217.837 197.931 1.00 58.72  ? 1   U     F "H1'"  1 
ATOM   814  H H3     . U     D 2 1   ? 279.723 214.105 199.851 1.00 57.28  ? 1   U     F H3     1 
ATOM   815  H H5     . U     D 2 1   ? 276.002 214.528 201.043 1.00 57.63  ? 1   U     F H5     1 
ATOM   816  H H6     . U     D 2 1   ? 275.934 216.439 199.860 1.00 58.62  ? 1   U     F H6     1 
ATOM   817  P P      . C     D 2 2   ? 276.859 220.964 195.355 1.00 64.07  ? 2   C     F P      1 
ATOM   818  O OP1    . C     D 2 2   ? 278.025 221.248 194.482 1.00 63.14  ? 2   C     F OP1    1 
ATOM   819  O OP2    . C     D 2 2   ? 276.273 222.054 196.173 1.00 59.52  ? 2   C     F OP2    1 
ATOM   820  O "O5'"  . C     D 2 2   ? 275.700 220.340 194.456 1.00 61.91  ? 2   C     F "O5'"  1 
ATOM   821  C "C5'"  . C     D 2 2   ? 275.992 219.399 193.436 1.00 61.32  ? 2   C     F "C5'"  1 
ATOM   822  C "C4'"  . C     D 2 2   ? 275.184 219.656 192.187 1.00 61.78  ? 2   C     F "C4'"  1 
ATOM   823  O "O4'"  . C     D 2 2   ? 273.800 219.292 192.399 1.00 63.19  ? 2   C     F "O4'"  1 
ATOM   824  C "C3'"  . C     D 2 2   ? 275.121 221.099 191.716 1.00 61.77  ? 2   C     F "C3'"  1 
ATOM   825  O "O3'"  . C     D 2 2   ? 276.273 221.468 190.980 1.00 61.61  ? 2   C     F "O3'"  1 
ATOM   826  C "C2'"  . C     D 2 2   ? 273.842 221.134 190.887 1.00 64.29  ? 2   C     F "C2'"  1 
ATOM   827  O "O2'"  . C     D 2 2   ? 274.087 220.661 189.571 1.00 66.51  ? 2   C     F "O2'"  1 
ATOM   828  C "C1'"  . C     D 2 2   ? 272.964 220.110 191.610 1.00 63.17  ? 2   C     F "C1'"  1 
ATOM   829  N N1     . C     D 2 2   ? 271.916 220.714 192.467 1.00 62.21  ? 2   C     F N1     1 
ATOM   830  C C2     . C     D 2 2   ? 272.193 221.075 193.786 1.00 62.39  ? 2   C     F C2     1 
ATOM   831  O O2     . C     D 2 2   ? 273.331 220.905 194.236 1.00 62.18  ? 2   C     F O2     1 
ATOM   832  N N3     . C     D 2 2   ? 271.214 221.609 194.549 1.00 60.91  ? 2   C     F N3     1 
ATOM   833  C C4     . C     D 2 2   ? 269.994 221.784 194.044 1.00 60.37  ? 2   C     F C4     1 
ATOM   834  N N4     . C     D 2 2   ? 269.062 222.314 194.836 1.00 59.69  ? 2   C     F N4     1 
ATOM   835  C C5     . C     D 2 2   ? 269.679 221.421 192.706 1.00 61.49  ? 2   C     F C5     1 
ATOM   836  C C6     . C     D 2 2   ? 270.659 220.893 191.964 1.00 61.23  ? 2   C     F C6     1 
ATOM   837  P P      . U     D 2 3   ? 276.561 223.010 190.642 1.00 68.24  ? 3   U     F P      1 
ATOM   838  O OP1    . U     D 2 3   ? 277.895 223.093 190.001 1.00 67.36  ? 3   U     F OP1    1 
ATOM   839  O OP2    . U     D 2 3   ? 276.277 223.807 191.862 1.00 68.67  ? 3   U     F OP2    1 
ATOM   840  O "O5'"  . U     D 2 3   ? 275.467 223.376 189.544 1.00 62.24  ? 3   U     F "O5'"  1 
ATOM   841  C "C5'"  . U     D 2 3   ? 275.511 222.799 188.248 1.00 59.94  ? 3   U     F "C5'"  1 
ATOM   842  C "C4'"  . U     D 2 3   ? 274.287 223.163 187.448 1.00 60.03  ? 3   U     F "C4'"  1 
ATOM   843  O "O4'"  . U     D 2 3   ? 273.107 222.641 188.108 1.00 59.53  ? 3   U     F "O4'"  1 
ATOM   844  C "C3'"  . U     D 2 3   ? 274.010 224.652 187.307 1.00 58.86  ? 3   U     F "C3'"  1 
ATOM   845  O "O3'"  . U     D 2 3   ? 274.752 225.246 186.259 1.00 57.70  ? 3   U     F "O3'"  1 
ATOM   846  C "C2'"  . U     D 2 3   ? 272.505 224.698 187.088 1.00 59.04  ? 3   U     F "C2'"  1 
ATOM   847  O "O2'"  . U     D 2 3   ? 272.188 224.378 185.742 1.00 59.65  ? 3   U     F "O2'"  1 
ATOM   848  C "C1'"  . U     D 2 3   ? 272.035 223.547 187.975 1.00 58.45  ? 3   U     F "C1'"  1 
ATOM   849  N N1     . U     D 2 3   ? 271.638 223.988 189.330 1.00 58.17  ? 3   U     F N1     1 
ATOM   850  C C2     . U     D 2 3   ? 270.314 224.302 189.552 1.00 58.93  ? 3   U     F C2     1 
ATOM   851  O O2     . U     D 2 3   ? 269.469 224.249 188.677 1.00 59.29  ? 3   U     F O2     1 
ATOM   852  N N3     . U     D 2 3   ? 270.016 224.686 190.836 1.00 57.31  ? 3   U     F N3     1 
ATOM   853  C C4     . U     D 2 3   ? 270.892 224.778 191.897 1.00 56.15  ? 3   U     F C4     1 
ATOM   854  O O4     . U     D 2 3   ? 270.475 225.138 192.996 1.00 55.91  ? 3   U     F O4     1 
ATOM   855  C C5     . U     D 2 3   ? 272.242 224.430 191.587 1.00 57.18  ? 3   U     F C5     1 
ATOM   856  C C6     . U     D 2 3   ? 272.559 224.053 190.346 1.00 57.89  ? 3   U     F C6     1 
ATOM   857  P P      . C     D 2 4   ? 274.745 226.840 186.066 1.00 61.24  ? 4   C     F P      1 
ATOM   858  O OP1    . C     D 2 4   ? 275.695 227.161 184.972 1.00 61.07  ? 4   C     F OP1    1 
ATOM   859  O OP2    . C     D 2 4   ? 274.914 227.477 187.395 1.00 61.42  ? 4   C     F OP2    1 
ATOM   860  O "O5'"  . C     D 2 4   ? 273.270 227.153 185.555 1.00 58.25  ? 4   C     F "O5'"  1 
ATOM   861  C "C5'"  . C     D 2 4   ? 272.849 226.765 184.257 1.00 54.95  ? 4   C     F "C5'"  1 
ATOM   862  C "C4'"  . C     D 2 4   ? 271.422 227.174 184.000 1.00 55.29  ? 4   C     F "C4'"  1 
ATOM   863  O "O4'"  . C     D 2 4   ? 270.547 226.520 184.952 1.00 56.96  ? 4   C     F "O4'"  1 
ATOM   864  C "C3'"  . C     D 2 4   ? 271.116 228.653 184.170 1.00 54.27  ? 4   C     F "C3'"  1 
ATOM   865  O "O3'"  . C     D 2 4   ? 271.470 229.418 183.033 1.00 54.25  ? 4   C     F "O3'"  1 
ATOM   866  C "C2'"  . C     D 2 4   ? 269.622 228.653 184.466 1.00 54.22  ? 4   C     F "C2'"  1 
ATOM   867  O "O2'"  . C     D 2 4   ? 268.876 228.496 183.269 1.00 54.39  ? 4   C     F "O2'"  1 
ATOM   868  C "C1'"  . C     D 2 4   ? 269.478 227.376 185.293 1.00 56.31  ? 4   C     F "C1'"  1 
ATOM   869  N N1     . C     D 2 4   ? 269.534 227.637 186.748 1.00 55.98  ? 4   C     F N1     1 
ATOM   870  C C2     . C     D 2 4   ? 268.358 227.960 187.423 1.00 55.58  ? 4   C     F C2     1 
ATOM   871  O O2     . C     D 2 4   ? 267.299 228.027 186.783 1.00 53.94  ? 4   C     F O2     1 
ATOM   872  N N3     . C     D 2 4   ? 268.402 228.190 188.753 1.00 55.99  ? 4   C     F N3     1 
ATOM   873  C C4     . C     D 2 4   ? 269.561 228.106 189.405 1.00 55.64  ? 4   C     F C4     1 
ATOM   874  N N4     . C     D 2 4   ? 269.559 228.344 190.716 1.00 55.20  ? 4   C     F N4     1 
ATOM   875  C C5     . C     D 2 4   ? 270.776 227.777 188.742 1.00 56.18  ? 4   C     F C5     1 
ATOM   876  C C6     . C     D 2 4   ? 270.716 227.550 187.425 1.00 56.69  ? 4   C     F C6     1 
ATOM   877  P P      . U     D 2 5   ? 272.330 230.764 183.197 1.00 56.35  ? 5   U     F P      1 
ATOM   878  O OP1    . U     D 2 5   ? 273.107 230.964 181.950 1.00 53.27  ? 5   U     F OP1    1 
ATOM   879  O OP2    . U     D 2 5   ? 273.032 230.710 184.503 1.00 55.61  ? 5   U     F OP2    1 
ATOM   880  O "O5'"  . U     D 2 5   ? 271.229 231.909 183.280 1.00 52.88  ? 5   U     F "O5'"  1 
ATOM   881  C "C5'"  . U     D 2 5   ? 270.137 231.924 182.376 1.00 52.11  ? 5   U     F "C5'"  1 
ATOM   882  C "C4'"  . U     D 2 5   ? 268.860 232.332 183.062 1.00 51.66  ? 5   U     F "C4'"  1 
ATOM   883  O "O4'"  . U     D 2 5   ? 268.962 233.709 183.496 1.00 52.92  ? 5   U     F "O4'"  1 
ATOM   884  C "C3'"  . U     D 2 5   ? 267.609 232.300 182.198 1.00 52.38  ? 5   U     F "C3'"  1 
ATOM   885  O "O3'"  . U     D 2 5   ? 267.039 231.007 182.130 1.00 54.85  ? 5   U     F "O3'"  1 
ATOM   886  C "C2'"  . U     D 2 5   ? 266.703 233.322 182.872 1.00 52.39  ? 5   U     F "C2'"  1 
ATOM   887  O "O2'"  . U     D 2 5   ? 266.063 232.749 184.002 1.00 53.32  ? 5   U     F "O2'"  1 
ATOM   888  C "C1'"  . U     D 2 5   ? 267.715 234.352 183.369 1.00 51.71  ? 5   U     F "C1'"  1 
ATOM   889  N N1     . U     D 2 5   ? 267.876 235.504 182.455 1.00 51.73  ? 5   U     F N1     1 
ATOM   890  C C2     . U     D 2 5   ? 266.889 236.467 182.440 1.00 50.59  ? 5   U     F C2     1 
ATOM   891  O O2     . U     D 2 5   ? 265.884 236.392 183.121 1.00 50.32  ? 5   U     F O2     1 
ATOM   892  N N3     . U     D 2 5   ? 267.117 237.515 181.587 1.00 49.94  ? 5   U     F N3     1 
ATOM   893  C C4     . U     D 2 5   ? 268.215 237.698 180.774 1.00 50.32  ? 5   U     F C4     1 
ATOM   894  O O4     . U     D 2 5   ? 268.279 238.696 180.059 1.00 53.08  ? 5   U     F O4     1 
ATOM   895  C C5     . U     D 2 5   ? 269.198 236.665 180.855 1.00 49.02  ? 5   U     F C5     1 
ATOM   896  C C6     . U     D 2 5   ? 269.001 235.632 181.677 1.00 52.19  ? 5   U     F C6     1 
ATOM   897  P P      . C     D 2 6   ? 266.572 230.395 180.723 1.00 54.89  ? 6   C     F P      1 
ATOM   898  O OP1    . C     D 2 6   ? 266.089 229.015 180.976 1.00 54.98  ? 6   C     F OP1    1 
ATOM   899  O OP2    . C     D 2 6   ? 267.649 230.627 179.730 1.00 56.33  ? 6   C     F OP2    1 
ATOM   900  O "O5'"  . C     D 2 6   ? 265.322 231.292 180.316 1.00 53.00  ? 6   C     F "O5'"  1 
ATOM   901  C "C5'"  . C     D 2 6   ? 264.195 231.398 181.171 1.00 50.76  ? 6   C     F "C5'"  1 
ATOM   902  C "C4'"  . C     D 2 6   ? 263.326 232.568 180.790 1.00 51.34  ? 6   C     F "C4'"  1 
ATOM   903  O "O4'"  . C     D 2 6   ? 264.064 233.806 180.960 1.00 53.22  ? 6   C     F "O4'"  1 
ATOM   904  C "C3'"  . C     D 2 6   ? 262.875 232.615 179.341 1.00 54.01  ? 6   C     F "C3'"  1 
ATOM   905  O "O3'"  . C     D 2 6   ? 261.788 231.754 179.059 1.00 55.40  ? 6   C     F "O3'"  1 
ATOM   906  C "C2'"  . C     D 2 6   ? 262.564 234.091 179.147 1.00 52.92  ? 6   C     F "C2'"  1 
ATOM   907  O "O2'"  . C     D 2 6   ? 261.325 234.423 179.753 1.00 52.56  ? 6   C     F "O2'"  1 
ATOM   908  C "C1'"  . C     D 2 6   ? 263.683 234.733 179.964 1.00 51.88  ? 6   C     F "C1'"  1 
ATOM   909  N N1     . C     D 2 6   ? 264.864 235.043 179.127 1.00 51.04  ? 6   C     F N1     1 
ATOM   910  C C2     . C     D 2 6   ? 264.901 236.260 178.445 1.00 51.33  ? 6   C     F C2     1 
ATOM   911  O O2     . C     D 2 6   ? 263.947 237.040 178.567 1.00 55.27  ? 6   C     F O2     1 
ATOM   912  N N3     . C     D 2 6   ? 265.972 236.560 177.677 1.00 47.32  ? 6   C     F N3     1 
ATOM   913  C C4     . C     D 2 6   ? 266.977 235.694 177.573 1.00 49.32  ? 6   C     F C4     1 
ATOM   914  N N4     . C     D 2 6   ? 268.013 236.029 176.803 1.00 49.56  ? 6   C     F N4     1 
ATOM   915  C C5     . C     D 2 6   ? 266.966 234.444 178.255 1.00 51.07  ? 6   C     F C5     1 
ATOM   916  C C6     . C     D 2 6   ? 265.900 234.161 179.012 1.00 51.21  ? 6   C     F C6     1 
ATOM   917  P P      . U     D 2 7   ? 261.763 230.933 177.679 1.00 60.51  ? 7   U     F P      1 
ATOM   918  O OP1    . U     D 2 7   ? 263.011 230.136 177.595 1.00 58.84  ? 7   U     F OP1    1 
ATOM   919  O OP2    . U     D 2 7   ? 261.430 231.883 176.588 1.00 56.05  ? 7   U     F OP2    1 
ATOM   920  O "O5'"  . U     D 2 7   ? 260.549 229.919 177.852 1.00 57.58  ? 7   U     F "O5'"  1 
ATOM   921  C "C5'"  . U     D 2 7   ? 260.585 228.899 178.842 1.00 54.20  ? 7   U     F "C5'"  1 
ATOM   922  C "C4'"  . U     D 2 7   ? 259.760 227.703 178.438 1.00 58.76  ? 7   U     F "C4'"  1 
ATOM   923  O "O4'"  . U     D 2 7   ? 258.348 228.025 178.567 1.00 62.09  ? 7   U     F "O4'"  1 
ATOM   924  C "C3'"  . U     D 2 7   ? 259.960 227.231 176.999 1.00 56.43  ? 7   U     F "C3'"  1 
ATOM   925  O "O3'"  . U     D 2 7   ? 259.842 225.810 176.947 1.00 49.45  ? 7   U     F "O3'"  1 
ATOM   926  C "C2'"  . U     D 2 7   ? 258.780 227.867 176.270 1.00 57.59  ? 7   U     F "C2'"  1 
ATOM   927  O "O2'"  . U     D 2 7   ? 258.396 227.203 175.086 1.00 57.94  ? 7   U     F "O2'"  1 
ATOM   928  C "C1'"  . U     D 2 7   ? 257.693 227.796 177.335 1.00 57.85  ? 7   U     F "C1'"  1 
ATOM   929  N N1     . U     D 2 7   ? 256.626 228.797 177.183 1.00 55.16  ? 7   U     F N1     1 
ATOM   930  C C2     . U     D 2 7   ? 256.934 230.124 177.396 1.00 57.32  ? 7   U     F C2     1 
ATOM   931  O O2     . U     D 2 7   ? 258.050 230.505 177.696 1.00 61.45  ? 7   U     F O2     1 
ATOM   932  N N3     . U     D 2 7   ? 255.886 230.995 177.241 1.00 55.07  ? 7   U     F N3     1 
ATOM   933  C C4     . U     D 2 7   ? 254.587 230.680 176.906 1.00 53.35  ? 7   U     F C4     1 
ATOM   934  O O4     . U     D 2 7   ? 253.752 231.578 176.804 1.00 53.16  ? 7   U     F O4     1 
ATOM   935  C C5     . U     D 2 7   ? 254.346 229.287 176.706 1.00 55.18  ? 7   U     F C5     1 
ATOM   936  C C6     . U     D 2 7   ? 255.349 228.417 176.849 1.00 55.96  ? 7   U     F C6     1 
ATOM   937  N N      . THR   E 1 3   ? 251.150 255.498 219.827 1.00 55.55  ? 15  THR   B N      1 
ATOM   938  C CA     . THR   E 1 3   ? 252.585 255.685 219.992 1.00 59.31  ? 15  THR   B CA     1 
ATOM   939  C C      . THR   E 1 3   ? 252.896 256.034 221.442 1.00 63.12  ? 15  THR   B C      1 
ATOM   940  O O      . THR   E 1 3   ? 251.985 256.191 222.253 1.00 69.44  ? 15  THR   B O      1 
ATOM   941  C CB     . THR   E 1 3   ? 253.127 256.787 219.062 1.00 58.35  ? 15  THR   B CB     1 
ATOM   942  O OG1    . THR   E 1 3   ? 252.486 256.691 217.784 1.00 66.86  ? 15  THR   B OG1    1 
ATOM   943  C CG2    . THR   E 1 3   ? 254.624 256.634 218.868 1.00 47.96  ? 15  THR   B CG2    1 
ATOM   944  N N      . ASP   E 1 4   ? 254.185 256.139 221.762 1.00 60.33  ? 16  ASP   B N      1 
ATOM   945  C CA     . ASP   E 1 4   ? 254.637 256.417 223.121 1.00 64.46  ? 16  ASP   B CA     1 
ATOM   946  C C      . ASP   E 1 4   ? 254.478 255.155 223.961 1.00 62.89  ? 16  ASP   B C      1 
ATOM   947  O O      . ASP   E 1 4   ? 254.935 255.089 225.105 1.00 65.40  ? 16  ASP   B O      1 
ATOM   948  C CB     . ASP   E 1 4   ? 253.850 257.590 223.716 1.00 76.78  ? 16  ASP   B CB     1 
ATOM   949  C CG     . ASP   E 1 4   ? 254.256 257.916 225.143 1.00 84.20  ? 16  ASP   B CG     1 
ATOM   950  O OD1    . ASP   E 1 4   ? 255.269 257.373 225.628 1.00 81.05  ? 16  ASP   B OD1    1 
ATOM   951  O OD2    . ASP   E 1 4   ? 253.552 258.723 225.785 1.00 90.22  ? 16  ASP   B OD2    1 
ATOM   952  N N      . GLY   E 1 5   ? 253.842 254.140 223.386 1.00 60.89  ? 17  GLY   B N      1 
ATOM   953  C CA     . GLY   E 1 5   ? 253.760 252.829 223.993 1.00 56.56  ? 17  GLY   B CA     1 
ATOM   954  C C      . GLY   E 1 5   ? 254.316 251.792 223.043 1.00 56.76  ? 17  GLY   B C      1 
ATOM   955  O O      . GLY   E 1 5   ? 254.770 250.722 223.458 1.00 55.27  ? 17  GLY   B O      1 
ATOM   956  N N      . GLU   E 1 6   ? 254.287 252.114 221.754 1.00 59.68  ? 18  GLU   B N      1 
ATOM   957  C CA     . GLU   E 1 6   ? 254.891 251.284 220.725 1.00 52.06  ? 18  GLU   B CA     1 
ATOM   958  C C      . GLU   E 1 6   ? 256.367 251.591 220.520 1.00 51.41  ? 18  GLU   B C      1 
ATOM   959  O O      . GLU   E 1 6   ? 257.034 250.874 219.768 1.00 50.87  ? 18  GLU   B O      1 
ATOM   960  C CB     . GLU   E 1 6   ? 254.132 251.450 219.406 1.00 52.51  ? 18  GLU   B CB     1 
ATOM   961  C CG     . GLU   E 1 6   ? 252.723 251.984 219.583 1.00 59.65  ? 18  GLU   B CG     1 
ATOM   962  C CD     . GLU   E 1 6   ? 251.967 252.080 218.276 1.00 73.10  ? 18  GLU   B CD     1 
ATOM   963  O OE1    . GLU   E 1 6   ? 252.617 252.236 217.224 1.00 75.70  ? 18  GLU   B OE1    1 
ATOM   964  O OE2    . GLU   E 1 6   ? 250.721 251.998 218.301 1.00 80.28  ? 18  GLU   B OE2    1 
ATOM   965  N N      . ARG   E 1 7   ? 256.888 252.641 221.161 1.00 51.78  ? 19  ARG   B N      1 
ATOM   966  C CA     . ARG   E 1 7   ? 258.334 252.828 221.208 1.00 47.54  ? 19  ARG   B CA     1 
ATOM   967  C C      . ARG   E 1 7   ? 259.007 251.667 221.925 1.00 49.05  ? 19  ARG   B C      1 
ATOM   968  O O      . ARG   E 1 7   ? 260.003 251.120 221.440 1.00 50.46  ? 19  ARG   B O      1 
ATOM   969  C CB     . ARG   E 1 7   ? 258.679 254.140 221.908 1.00 51.31  ? 19  ARG   B CB     1 
ATOM   970  C CG     . ARG   E 1 7   ? 258.879 255.320 220.991 1.00 52.51  ? 19  ARG   B CG     1 
ATOM   971  C CD     . ARG   E 1 7   ? 259.754 256.350 221.675 1.00 51.45  ? 19  ARG   B CD     1 
ATOM   972  N NE     . ARG   E 1 7   ? 259.212 256.732 222.972 1.00 49.69  ? 19  ARG   B NE     1 
ATOM   973  C CZ     . ARG   E 1 7   ? 259.679 257.723 223.716 1.00 58.55  ? 19  ARG   B CZ     1 
ATOM   974  N NH1    . ARG   E 1 7   ? 260.704 258.459 223.321 1.00 61.83  ? 19  ARG   B NH1    1 
ATOM   975  N NH2    . ARG   E 1 7   ? 259.103 257.983 224.886 1.00 65.45  ? 19  ARG   B NH2    1 
ATOM   976  N N      . GLN   E 1 8   ? 258.473 251.275 223.085 1.00 47.48  ? 20  GLN   B N      1 
ATOM   977  C CA     . GLN   E 1 8   ? 259.004 250.108 223.779 1.00 49.08  ? 20  GLN   B CA     1 
ATOM   978  C C      . GLN   E 1 8   ? 258.945 248.876 222.893 1.00 48.22  ? 20  GLN   B C      1 
ATOM   979  O O      . GLN   E 1 8   ? 259.933 248.146 222.766 1.00 49.70  ? 20  GLN   B O      1 
ATOM   980  C CB     . GLN   E 1 8   ? 258.234 249.865 225.076 1.00 55.15  ? 20  GLN   B CB     1 
ATOM   981  C CG     . GLN   E 1 8   ? 259.108 249.497 226.262 1.00 49.27  ? 20  GLN   B CG     1 
ATOM   982  C CD     . GLN   E 1 8   ? 260.302 250.409 226.409 1.00 56.60  ? 20  GLN   B CD     1 
ATOM   983  O OE1    . GLN   E 1 8   ? 260.321 251.517 225.876 1.00 59.16  ? 20  GLN   B OE1    1 
ATOM   984  N NE2    . GLN   E 1 8   ? 261.311 249.946 227.135 1.00 61.14  ? 20  GLN   B NE2    1 
ATOM   985  N N      . ASN   E 1 9   ? 257.799 248.641 222.255 1.00 45.88  ? 21  ASN   B N      1 
ATOM   986  C CA     . ASN   E 1 9   ? 257.661 247.469 221.400 1.00 47.29  ? 21  ASN   B CA     1 
ATOM   987  C C      . ASN   E 1 9   ? 258.617 247.547 220.217 1.00 45.75  ? 21  ASN   B C      1 
ATOM   988  O O      . ASN   E 1 9   ? 259.204 246.537 219.815 1.00 46.36  ? 21  ASN   B O      1 
ATOM   989  C CB     . ASN   E 1 9   ? 256.211 247.336 220.933 1.00 49.40  ? 21  ASN   B CB     1 
ATOM   990  C CG     . ASN   E 1 9   ? 255.979 246.102 220.092 1.00 56.14  ? 21  ASN   B CG     1 
ATOM   991  O OD1    . ASN   E 1 9   ? 256.818 245.205 220.039 1.00 65.96  ? 21  ASN   B OD1    1 
ATOM   992  N ND2    . ASN   E 1 9   ? 254.827 246.045 219.435 1.00 50.51  ? 21  ASN   B ND2    1 
ATOM   993  N N      . ALA   E 1 10  ? 258.796 248.745 219.653 1.00 45.85  ? 22  ALA   B N      1 
ATOM   994  C CA     . ALA   E 1 10  ? 259.771 248.920 218.581 1.00 44.21  ? 22  ALA   B CA     1 
ATOM   995  C C      . ALA   E 1 10  ? 261.183 248.630 219.070 1.00 46.04  ? 22  ALA   B C      1 
ATOM   996  O O      . ALA   E 1 10  ? 261.979 248.005 218.360 1.00 44.84  ? 22  ALA   B O      1 
ATOM   997  C CB     . ALA   E 1 10  ? 259.679 250.335 218.012 1.00 42.73  ? 22  ALA   B CB     1 
ATOM   998  N N      . THR   E 1 11  ? 261.518 249.085 220.279 1.00 48.05  ? 23  THR   B N      1 
ATOM   999  C CA     . THR   E 1 11  ? 262.834 248.792 220.838 1.00 45.75  ? 23  THR   B CA     1 
ATOM   1000 C C      . THR   E 1 11  ? 263.007 247.299 221.085 1.00 45.40  ? 23  THR   B C      1 
ATOM   1001 O O      . THR   E 1 11  ? 264.085 246.745 220.844 1.00 44.28  ? 23  THR   B O      1 
ATOM   1002 C CB     . THR   E 1 11  ? 263.048 249.578 222.129 1.00 48.50  ? 23  THR   B CB     1 
ATOM   1003 O OG1    . THR   E 1 11  ? 263.042 250.980 221.841 1.00 47.83  ? 23  THR   B OG1    1 
ATOM   1004 C CG2    . THR   E 1 11  ? 264.382 249.210 222.752 1.00 49.30  ? 23  THR   B CG2    1 
ATOM   1005 N N      . GLU   E 1 12  ? 261.959 246.630 221.575 1.00 46.80  ? 24  GLU   B N      1 
ATOM   1006 C CA     . GLU   E 1 12  ? 262.036 245.187 221.779 1.00 45.95  ? 24  GLU   B CA     1 
ATOM   1007 C C      . GLU   E 1 12  ? 262.348 244.463 220.477 1.00 46.26  ? 24  GLU   B C      1 
ATOM   1008 O O      . GLU   E 1 12  ? 263.220 243.588 220.438 1.00 44.62  ? 24  GLU   B O      1 
ATOM   1009 C CB     . GLU   E 1 12  ? 260.725 244.660 222.366 1.00 48.51  ? 24  GLU   B CB     1 
ATOM   1010 C CG     . GLU   E 1 12  ? 260.137 245.497 223.479 1.00 46.98  ? 24  GLU   B CG     1 
ATOM   1011 C CD     . GLU   E 1 12  ? 260.742 245.172 224.822 1.00 53.58  ? 24  GLU   B CD     1 
ATOM   1012 O OE1    . GLU   E 1 12  ? 261.976 245.016 224.894 1.00 59.56  ? 24  GLU   B OE1    1 
ATOM   1013 O OE2    . GLU   E 1 12  ? 259.982 245.071 225.807 1.00 58.41  ? 24  GLU   B OE2    1 
ATOM   1014 N N      . ILE   E 1 13  ? 261.643 244.813 219.400 1.00 44.08  ? 25  ILE   B N      1 
ATOM   1015 C CA     . ILE   E 1 13  ? 261.843 244.130 218.125 1.00 42.48  ? 25  ILE   B CA     1 
ATOM   1016 C C      . ILE   E 1 13  ? 263.255 244.364 217.609 1.00 43.25  ? 25  ILE   B C      1 
ATOM   1017 O O      . ILE   E 1 13  ? 263.895 243.453 217.071 1.00 42.88  ? 25  ILE   B O      1 
ATOM   1018 C CB     . ILE   E 1 13  ? 260.785 244.581 217.102 1.00 43.23  ? 25  ILE   B CB     1 
ATOM   1019 C CG1    . ILE   E 1 13  ? 259.380 244.403 217.674 1.00 42.55  ? 25  ILE   B CG1    1 
ATOM   1020 C CG2    . ILE   E 1 13  ? 260.934 243.801 215.808 1.00 51.68  ? 25  ILE   B CG2    1 
ATOM   1021 C CD1    . ILE   E 1 13  ? 259.113 243.017 218.203 1.00 42.38  ? 25  ILE   B CD1    1 
ATOM   1022 N N      . ARG   E 1 14  ? 263.761 245.589 217.758 1.00 45.28  ? 26  ARG   B N      1 
ATOM   1023 C CA     . ARG   E 1 14  ? 265.105 245.891 217.279 1.00 44.87  ? 26  ARG   B CA     1 
ATOM   1024 C C      . ARG   E 1 14  ? 266.143 245.013 217.962 1.00 45.03  ? 26  ARG   B C      1 
ATOM   1025 O O      . ARG   E 1 14  ? 267.070 244.516 217.313 1.00 46.57  ? 26  ARG   B O      1 
ATOM   1026 C CB     . ARG   E 1 14  ? 265.417 247.369 217.501 1.00 42.17  ? 26  ARG   B CB     1 
ATOM   1027 C CG     . ARG   E 1 14  ? 264.852 248.279 216.433 1.00 41.62  ? 26  ARG   B CG     1 
ATOM   1028 C CD     . ARG   E 1 14  ? 265.390 249.684 216.579 1.00 43.23  ? 26  ARG   B CD     1 
ATOM   1029 N NE     . ARG   E 1 14  ? 266.099 250.120 215.384 1.00 42.88  ? 26  ARG   B NE     1 
ATOM   1030 C CZ     . ARG   E 1 14  ? 267.416 250.243 215.304 1.00 44.85  ? 26  ARG   B CZ     1 
ATOM   1031 N NH1    . ARG   E 1 14  ? 268.198 249.975 216.336 1.00 44.52  ? 26  ARG   B NH1    1 
ATOM   1032 N NH2    . ARG   E 1 14  ? 267.962 250.651 214.163 1.00 47.01  ? 26  ARG   B NH2    1 
ATOM   1033 N N      . ALA   E 1 15  ? 266.009 244.815 219.275 1.00 45.34  ? 27  ALA   B N      1 
ATOM   1034 C CA     . ALA   E 1 15  ? 266.952 243.964 219.991 1.00 45.74  ? 27  ALA   B CA     1 
ATOM   1035 C C      . ALA   E 1 15  ? 266.863 242.516 219.523 1.00 44.99  ? 27  ALA   B C      1 
ATOM   1036 O O      . ALA   E 1 15  ? 267.888 241.843 219.368 1.00 45.04  ? 27  ALA   B O      1 
ATOM   1037 C CB     . ALA   E 1 15  ? 266.704 244.058 221.496 1.00 49.18  ? 27  ALA   B CB     1 
ATOM   1038 N N      . SER   E 1 16  ? 265.646 242.016 219.298 1.00 42.76  ? 28  SER   B N      1 
ATOM   1039 C CA     . SER   E 1 16  ? 265.484 240.621 218.900 1.00 42.69  ? 28  SER   B CA     1 
ATOM   1040 C C      . SER   E 1 16  ? 266.092 240.365 217.526 1.00 41.93  ? 28  SER   B C      1 
ATOM   1041 O O      . SER   E 1 16  ? 266.749 239.341 217.309 1.00 42.42  ? 28  SER   B O      1 
ATOM   1042 C CB     . SER   E 1 16  ? 264.004 240.237 218.919 1.00 42.35  ? 28  SER   B CB     1 
ATOM   1043 O OG     . SER   E 1 16  ? 263.341 240.698 217.757 1.00 52.76  ? 28  SER   B OG     1 
ATOM   1044 N N      . VAL   E 1 17  ? 265.882 241.283 216.582 1.00 41.08  ? 29  VAL   B N      1 
ATOM   1045 C CA     . VAL   E 1 17  ? 266.501 241.129 215.270 1.00 41.61  ? 29  VAL   B CA     1 
ATOM   1046 C C      . VAL   E 1 17  ? 268.009 241.309 215.365 1.00 42.15  ? 29  VAL   B C      1 
ATOM   1047 O O      . VAL   E 1 17  ? 268.768 240.617 214.676 1.00 44.07  ? 29  VAL   B O      1 
ATOM   1048 C CB     . VAL   E 1 17  ? 265.879 242.107 214.258 1.00 40.10  ? 29  VAL   B CB     1 
ATOM   1049 C CG1    . VAL   E 1 17  ? 264.420 241.770 214.025 1.00 40.28  ? 29  VAL   B CG1    1 
ATOM   1050 C CG2    . VAL   E 1 17  ? 266.022 243.532 214.748 1.00 44.44  ? 29  VAL   B CG2    1 
ATOM   1051 N N      . GLY   E 1 18  ? 268.471 242.231 216.209 1.00 39.90  ? 30  GLY   B N      1 
ATOM   1052 C CA     . GLY   E 1 18  ? 269.903 242.389 216.401 1.00 41.10  ? 30  GLY   B CA     1 
ATOM   1053 C C      . GLY   E 1 18  ? 270.549 241.147 216.982 1.00 43.18  ? 30  GLY   B C      1 
ATOM   1054 O O      . GLY   E 1 18  ? 271.688 240.813 216.645 1.00 42.90  ? 30  GLY   B O      1 
ATOM   1055 N N      . LYS   E 1 19  ? 269.838 240.452 217.870 1.00 44.10  ? 31  LYS   B N      1 
ATOM   1056 C CA     . LYS   E 1 19  ? 270.349 239.197 218.406 1.00 43.87  ? 31  LYS   B CA     1 
ATOM   1057 C C      . LYS   E 1 19  ? 270.452 238.130 217.324 1.00 42.81  ? 31  LYS   B C      1 
ATOM   1058 O O      . LYS   E 1 19  ? 271.401 237.340 217.322 1.00 41.55  ? 31  LYS   B O      1 
ATOM   1059 C CB     . LYS   E 1 19  ? 269.459 238.727 219.556 1.00 43.47  ? 31  LYS   B CB     1 
ATOM   1060 C CG     . LYS   E 1 19  ? 269.827 237.375 220.129 1.00 49.44  ? 31  LYS   B CG     1 
ATOM   1061 C CD     . LYS   E 1 19  ? 268.852 236.967 221.220 1.00 47.06  ? 31  LYS   B CD     1 
ATOM   1062 C CE     . LYS   E 1 19  ? 269.428 237.221 222.601 1.00 47.67  ? 31  LYS   B CE     1 
ATOM   1063 N NZ     . LYS   E 1 19  ? 270.911 237.137 222.604 1.00 55.34  ? 31  LYS   B NZ     1 
ATOM   1064 N N      . MET   E 1 20  ? 269.489 238.094 216.401 1.00 42.90  ? 32  MET   B N      1 
ATOM   1065 C CA     . MET   E 1 20  ? 269.578 237.180 215.267 1.00 40.76  ? 32  MET   B CA     1 
ATOM   1066 C C      . MET   E 1 20  ? 270.768 237.519 214.378 1.00 40.98  ? 32  MET   B C      1 
ATOM   1067 O O      . MET   E 1 20  ? 271.506 236.625 213.948 1.00 40.75  ? 32  MET   B O      1 
ATOM   1068 C CB     . MET   E 1 20  ? 268.279 237.224 214.464 1.00 37.39  ? 32  MET   B CB     1 
ATOM   1069 C CG     . MET   E 1 20  ? 268.455 236.960 212.983 1.00 37.87  ? 32  MET   B CG     1 
ATOM   1070 S SD     . MET   E 1 20  ? 267.181 237.754 211.986 1.00 48.50  ? 32  MET   B SD     1 
ATOM   1071 C CE     . MET   E 1 20  ? 265.708 236.982 212.637 1.00 41.70  ? 32  MET   B CE     1 
ATOM   1072 N N      . ILE   E 1 21  ? 270.973 238.806 214.095 1.00 40.80  ? 33  ILE   B N      1 
ATOM   1073 C CA     . ILE   E 1 21  ? 272.094 239.209 213.251 1.00 40.12  ? 33  ILE   B CA     1 
ATOM   1074 C C      . ILE   E 1 21  ? 273.415 238.884 213.933 1.00 42.93  ? 33  ILE   B C      1 
ATOM   1075 O O      . ILE   E 1 21  ? 274.396 238.516 213.277 1.00 42.66  ? 33  ILE   B O      1 
ATOM   1076 C CB     . ILE   E 1 21  ? 271.991 240.704 212.899 1.00 38.25  ? 33  ILE   B CB     1 
ATOM   1077 C CG1    . ILE   E 1 21  ? 270.734 240.974 212.072 1.00 37.07  ? 33  ILE   B CG1    1 
ATOM   1078 C CG2    . ILE   E 1 21  ? 273.226 241.154 212.143 1.00 39.15  ? 33  ILE   B CG2    1 
ATOM   1079 C CD1    . ILE   E 1 21  ? 270.453 239.922 211.033 1.00 41.47  ? 33  ILE   B CD1    1 
ATOM   1080 N N      . ASP   E 1 22  ? 273.464 239.021 215.260 1.00 42.69  ? 34  ASP   B N      1 
ATOM   1081 C CA     . ASP   E 1 22  ? 274.675 238.677 215.998 1.00 41.85  ? 34  ASP   B CA     1 
ATOM   1082 C C      . ASP   E 1 22  ? 275.001 237.197 215.865 1.00 42.39  ? 34  ASP   B C      1 
ATOM   1083 O O      . ASP   E 1 22  ? 276.166 236.823 215.687 1.00 42.65  ? 34  ASP   B O      1 
ATOM   1084 C CB     . ASP   E 1 22  ? 274.519 239.057 217.469 1.00 43.73  ? 34  ASP   B CB     1 
ATOM   1085 C CG     . ASP   E 1 22  ? 275.218 240.352 217.811 1.00 52.51  ? 34  ASP   B CG     1 
ATOM   1086 O OD1    . ASP   E 1 22  ? 275.689 241.037 216.880 1.00 55.08  ? 34  ASP   B OD1    1 
ATOM   1087 O OD2    . ASP   E 1 22  ? 275.297 240.686 219.011 1.00 57.06  ? 34  ASP   B OD2    1 
ATOM   1088 N N      . GLY   E 1 23  ? 273.986 236.336 215.958 1.00 43.12  ? 35  GLY   B N      1 
ATOM   1089 C CA     . GLY   E 1 23  ? 274.230 234.911 215.817 1.00 41.24  ? 35  GLY   B CA     1 
ATOM   1090 C C      . GLY   E 1 23  ? 274.799 234.554 214.458 1.00 40.33  ? 35  GLY   B C      1 
ATOM   1091 O O      . GLY   E 1 23  ? 275.731 233.755 214.350 1.00 40.16  ? 35  GLY   B O      1 
ATOM   1092 N N      . ILE   E 1 24  ? 274.247 235.149 213.400 1.00 40.16  ? 36  ILE   B N      1 
ATOM   1093 C CA     . ILE   E 1 24  ? 274.741 234.877 212.054 1.00 38.80  ? 36  ILE   B CA     1 
ATOM   1094 C C      . ILE   E 1 24  ? 276.199 235.299 211.933 1.00 39.48  ? 36  ILE   B C      1 
ATOM   1095 O O      . ILE   E 1 24  ? 277.034 234.568 211.388 1.00 41.33  ? 36  ILE   B O      1 
ATOM   1096 C CB     . ILE   E 1 24  ? 273.860 235.579 211.006 1.00 39.49  ? 36  ILE   B CB     1 
ATOM   1097 C CG1    . ILE   E 1 24  ? 272.441 235.016 211.037 1.00 38.77  ? 36  ILE   B CG1    1 
ATOM   1098 C CG2    . ILE   E 1 24  ? 274.458 235.419 209.622 1.00 44.07  ? 36  ILE   B CG2    1 
ATOM   1099 C CD1    . ILE   E 1 24  ? 271.517 235.653 210.031 1.00 38.02  ? 36  ILE   B CD1    1 
ATOM   1100 N N      . GLY   E 1 25  ? 276.527 236.489 212.437 1.00 38.73  ? 37  GLY   B N      1 
ATOM   1101 C CA     . GLY   E 1 25  ? 277.908 236.937 212.399 1.00 38.90  ? 37  GLY   B CA     1 
ATOM   1102 C C      . GLY   E 1 25  ? 278.819 236.093 213.268 1.00 39.87  ? 37  GLY   B C      1 
ATOM   1103 O O      . GLY   E 1 25  ? 279.916 235.714 212.849 1.00 40.44  ? 37  GLY   B O      1 
ATOM   1104 N N      . ARG   E 1 26  ? 278.377 235.781 214.487 1.00 41.83  ? 38  ARG   B N      1 
ATOM   1105 C CA     . ARG   E 1 26  ? 279.185 234.948 215.371 1.00 40.26  ? 38  ARG   B CA     1 
ATOM   1106 C C      . ARG   E 1 26  ? 279.389 233.561 214.779 1.00 37.18  ? 38  ARG   B C      1 
ATOM   1107 O O      . ARG   E 1 26  ? 280.482 232.991 214.875 1.00 34.70  ? 38  ARG   B O      1 
ATOM   1108 C CB     . ARG   E 1 26  ? 278.532 234.862 216.751 1.00 40.09  ? 38  ARG   B CB     1 
ATOM   1109 C CG     . ARG   E 1 26  ? 279.239 235.680 217.817 1.00 40.45  ? 38  ARG   B CG     1 
ATOM   1110 C CD     . ARG   E 1 26  ? 278.255 236.368 218.748 1.00 40.27  ? 38  ARG   B CD     1 
ATOM   1111 N NE     . ARG   E 1 26  ? 277.164 235.490 219.150 1.00 42.62  ? 38  ARG   B NE     1 
ATOM   1112 C CZ     . ARG   E 1 26  ? 276.084 235.893 219.804 1.00 44.23  ? 38  ARG   B CZ     1 
ATOM   1113 N NH1    . ARG   E 1 26  ? 275.915 237.159 220.144 1.00 42.65  ? 38  ARG   B NH1    1 
ATOM   1114 N NH2    . ARG   E 1 26  ? 275.147 235.004 220.118 1.00 48.39  ? 38  ARG   B NH2    1 
ATOM   1115 N N      . PHE   E 1 27  ? 278.346 233.000 214.165 1.00 39.07  ? 39  PHE   B N      1 
ATOM   1116 C CA     . PHE   E 1 27  ? 278.482 231.698 213.523 1.00 39.41  ? 39  PHE   B CA     1 
ATOM   1117 C C      . PHE   E 1 27  ? 279.434 231.760 212.335 1.00 38.34  ? 39  PHE   B C      1 
ATOM   1118 O O      . PHE   E 1 27  ? 280.258 230.859 212.144 1.00 36.21  ? 39  PHE   B O      1 
ATOM   1119 C CB     . PHE   E 1 27  ? 277.114 231.178 213.085 1.00 39.27  ? 39  PHE   B CB     1 
ATOM   1120 C CG     . PHE   E 1 27  ? 277.191 230.011 212.154 1.00 40.13  ? 39  PHE   B CG     1 
ATOM   1121 C CD1    . PHE   E 1 27  ? 277.387 228.735 212.643 1.00 41.61  ? 39  PHE   B CD1    1 
ATOM   1122 C CD2    . PHE   E 1 27  ? 277.076 230.190 210.789 1.00 39.03  ? 39  PHE   B CD2    1 
ATOM   1123 C CE1    . PHE   E 1 27  ? 277.467 227.662 211.790 1.00 40.43  ? 39  PHE   B CE1    1 
ATOM   1124 C CE2    . PHE   E 1 27  ? 277.156 229.121 209.934 1.00 37.10  ? 39  PHE   B CE2    1 
ATOM   1125 C CZ     . PHE   E 1 27  ? 277.353 227.854 210.436 1.00 38.34  ? 39  PHE   B CZ     1 
ATOM   1126 N N      . TYR   E 1 28  ? 279.332 232.811 211.520 1.00 38.44  ? 40  TYR   B N      1 
ATOM   1127 C CA     . TYR   E 1 28  ? 280.204 232.919 210.355 1.00 37.96  ? 40  TYR   B CA     1 
ATOM   1128 C C      . TYR   E 1 28  ? 281.664 233.047 210.769 1.00 36.73  ? 40  TYR   B C      1 
ATOM   1129 O O      . TYR   E 1 28  ? 282.549 232.452 210.144 1.00 37.68  ? 40  TYR   B O      1 
ATOM   1130 C CB     . TYR   E 1 28  ? 279.782 234.102 209.486 1.00 39.31  ? 40  TYR   B CB     1 
ATOM   1131 C CG     . TYR   E 1 28  ? 280.497 234.156 208.159 1.00 39.06  ? 40  TYR   B CG     1 
ATOM   1132 C CD1    . TYR   E 1 28  ? 280.148 233.301 207.124 1.00 39.69  ? 40  TYR   B CD1    1 
ATOM   1133 C CD2    . TYR   E 1 28  ? 281.524 235.061 207.941 1.00 36.78  ? 40  TYR   B CD2    1 
ATOM   1134 C CE1    . TYR   E 1 28  ? 280.804 233.346 205.913 1.00 38.73  ? 40  TYR   B CE1    1 
ATOM   1135 C CE2    . TYR   E 1 28  ? 282.182 235.114 206.734 1.00 35.77  ? 40  TYR   B CE2    1 
ATOM   1136 C CZ     . TYR   E 1 28  ? 281.819 234.255 205.724 1.00 37.98  ? 40  TYR   B CZ     1 
ATOM   1137 O OH     . TYR   E 1 28  ? 282.474 234.306 204.518 1.00 43.88  ? 40  TYR   B OH     1 
ATOM   1138 N N      . ILE   E 1 29  ? 281.934 233.823 211.819 1.00 38.61  ? 41  ILE   B N      1 
ATOM   1139 C CA     . ILE   E 1 29  ? 283.300 233.968 212.311 1.00 37.12  ? 41  ILE   B CA     1 
ATOM   1140 C C      . ILE   E 1 29  ? 283.840 232.620 212.770 1.00 36.19  ? 41  ILE   B C      1 
ATOM   1141 O O      . ILE   E 1 29  ? 284.977 232.245 212.461 1.00 34.36  ? 41  ILE   B O      1 
ATOM   1142 C CB     . ILE   E 1 29  ? 283.351 235.009 213.442 1.00 36.03  ? 41  ILE   B CB     1 
ATOM   1143 C CG1    . ILE   E 1 29  ? 283.445 236.419 212.866 1.00 36.62  ? 41  ILE   B CG1    1 
ATOM   1144 C CG2    . ILE   E 1 29  ? 284.524 234.735 214.365 1.00 41.01  ? 41  ILE   B CG2    1 
ATOM   1145 C CD1    . ILE   E 1 29  ? 283.401 237.501 213.915 1.00 42.08  ? 41  ILE   B CD1    1 
ATOM   1146 N N      . GLN   E 1 30  ? 283.026 231.869 213.514 1.00 37.68  ? 42  GLN   B N      1 
ATOM   1147 C CA     . GLN   E 1 30  ? 283.451 230.555 213.982 1.00 37.04  ? 42  GLN   B CA     1 
ATOM   1148 C C      . GLN   E 1 30  ? 283.746 229.622 212.815 1.00 36.67  ? 42  GLN   B C      1 
ATOM   1149 O O      . GLN   E 1 30  ? 284.760 228.915 212.816 1.00 36.56  ? 42  GLN   B O      1 
ATOM   1150 C CB     . GLN   E 1 30  ? 282.378 229.958 214.892 1.00 37.12  ? 42  GLN   B CB     1 
ATOM   1151 C CG     . GLN   E 1 30  ? 282.827 228.769 215.723 1.00 35.41  ? 42  GLN   B CG     1 
ATOM   1152 C CD     . GLN   E 1 30  ? 284.293 228.825 216.089 1.00 38.97  ? 42  GLN   B CD     1 
ATOM   1153 O OE1    . GLN   E 1 30  ? 285.054 227.909 215.786 1.00 34.94  ? 42  GLN   B OE1    1 
ATOM   1154 N NE2    . GLN   E 1 30  ? 284.697 229.902 216.748 1.00 43.21  ? 42  GLN   B NE2    1 
ATOM   1155 N N      . MET   E 1 31  ? 282.876 229.614 211.804 1.00 37.91  ? 43  MET   B N      1 
ATOM   1156 C CA     . MET   E 1 31  ? 283.073 228.716 210.672 1.00 38.29  ? 43  MET   B CA     1 
ATOM   1157 C C      . MET   E 1 31  ? 284.284 229.127 209.846 1.00 38.69  ? 43  MET   B C      1 
ATOM   1158 O O      . MET   E 1 31  ? 285.000 228.270 209.316 1.00 40.57  ? 43  MET   B O      1 
ATOM   1159 C CB     . MET   E 1 31  ? 281.816 228.681 209.805 1.00 39.10  ? 43  MET   B CB     1 
ATOM   1160 C CG     . MET   E 1 31  ? 280.720 227.782 210.344 1.00 42.00  ? 43  MET   B CG     1 
ATOM   1161 S SD     . MET   E 1 31  ? 280.984 226.043 209.958 1.00 56.23  ? 43  MET   B SD     1 
ATOM   1162 C CE     . MET   E 1 31  ? 282.017 226.173 208.504 1.00 51.28  ? 43  MET   B CE     1 
ATOM   1163 N N      . CYS   E 1 32  ? 284.526 230.433 209.721 1.00 39.46  ? 44  CYS   B N      1 
ATOM   1164 C CA     . CYS   E 1 32  ? 285.685 230.898 208.968 1.00 36.68  ? 44  CYS   B CA     1 
ATOM   1165 C C      . CYS   E 1 32  ? 286.985 230.442 209.618 1.00 37.19  ? 44  CYS   B C      1 
ATOM   1166 O O      . CYS   E 1 32  ? 287.912 230.000 208.929 1.00 33.55  ? 44  CYS   B O      1 
ATOM   1167 C CB     . CYS   E 1 32  ? 285.653 232.421 208.842 1.00 34.57  ? 44  CYS   B CB     1 
ATOM   1168 S SG     . CYS   E 1 32  ? 284.890 233.024 207.325 1.00 45.98  ? 44  CYS   B SG     1 
ATOM   1169 N N      . THR   E 1 33  ? 287.073 230.539 210.945 1.00 38.86  ? 45  THR   B N      1 
ATOM   1170 C CA     . THR   E 1 33  ? 288.264 230.078 211.645 1.00 35.95  ? 45  THR   B CA     1 
ATOM   1171 C C      . THR   E 1 33  ? 288.375 228.562 211.671 1.00 38.38  ? 45  THR   B C      1 
ATOM   1172 O O      . THR   E 1 33  ? 289.476 228.043 211.880 1.00 40.11  ? 45  THR   B O      1 
ATOM   1173 C CB     . THR   E 1 33  ? 288.283 230.615 213.077 1.00 33.62  ? 45  THR   B CB     1 
ATOM   1174 O OG1    . THR   E 1 33  ? 287.293 229.936 213.858 1.00 37.63  ? 45  THR   B OG1    1 
ATOM   1175 C CG2    . THR   E 1 33  ? 287.996 232.105 213.093 1.00 34.17  ? 45  THR   B CG2    1 
ATOM   1176 N N      . GLU   E 1 34  ? 287.274 227.844 211.463 1.00 38.68  ? 46  GLU   B N      1 
ATOM   1177 C CA     . GLU   E 1 34  ? 287.308 226.389 211.456 1.00 39.19  ? 46  GLU   B CA     1 
ATOM   1178 C C      . GLU   E 1 34  ? 287.596 225.822 210.074 1.00 41.77  ? 46  GLU   B C      1 
ATOM   1179 O O      . GLU   E 1 34  ? 288.190 224.745 209.967 1.00 42.70  ? 46  GLU   B O      1 
ATOM   1180 C CB     . GLU   E 1 34  ? 285.986 225.831 211.984 1.00 37.86  ? 46  GLU   B CB     1 
ATOM   1181 C CG     . GLU   E 1 34  ? 285.951 224.322 212.078 1.00 44.00  ? 46  GLU   B CG     1 
ATOM   1182 C CD     . GLU   E 1 34  ? 285.001 223.833 213.146 1.00 46.55  ? 46  GLU   B CD     1 
ATOM   1183 O OE1    . GLU   E 1 34  ? 284.911 224.492 214.202 1.00 45.62  ? 46  GLU   B OE1    1 
ATOM   1184 O OE2    . GLU   E 1 34  ? 284.349 222.792 212.934 1.00 48.97  ? 46  GLU   B OE2    1 
ATOM   1185 N N      . LEU   E 1 35  ? 287.188 226.522 209.019 1.00 43.77  ? 47  LEU   B N      1 
ATOM   1186 C CA     . LEU   E 1 35  ? 287.539 226.159 207.655 1.00 40.10  ? 47  LEU   B CA     1 
ATOM   1187 C C      . LEU   E 1 35  ? 288.878 226.741 207.222 1.00 40.51  ? 47  LEU   B C      1 
ATOM   1188 O O      . LEU   E 1 35  ? 289.335 226.451 206.113 1.00 42.42  ? 47  LEU   B O      1 
ATOM   1189 C CB     . LEU   E 1 35  ? 286.441 226.617 206.691 1.00 40.89  ? 47  LEU   B CB     1 
ATOM   1190 C CG     . LEU   E 1 35  ? 285.253 225.669 206.526 1.00 43.66  ? 47  LEU   B CG     1 
ATOM   1191 C CD1    . LEU   E 1 35  ? 284.112 226.368 205.814 1.00 44.34  ? 47  LEU   B CD1    1 
ATOM   1192 C CD2    . LEU   E 1 35  ? 285.668 224.419 205.776 1.00 46.04  ? 47  LEU   B CD2    1 
ATOM   1193 N N      . LYS   E 1 36  ? 289.514 227.546 208.074 1.00 43.02  ? 48  LYS   B N      1 
ATOM   1194 C CA     . LYS   E 1 36  ? 290.821 228.139 207.793 1.00 41.77  ? 48  LYS   B CA     1 
ATOM   1195 C C      . LYS   E 1 36  ? 290.774 229.019 206.542 1.00 40.84  ? 48  LYS   B C      1 
ATOM   1196 O O      . LYS   E 1 36  ? 291.439 228.762 205.538 1.00 45.30  ? 48  LYS   B O      1 
ATOM   1197 C CB     . LYS   E 1 36  ? 291.890 227.051 207.669 1.00 38.85  ? 48  LYS   B CB     1 
ATOM   1198 C CG     . LYS   E 1 36  ? 292.377 226.518 209.002 1.00 36.48  ? 48  LYS   B CG     1 
ATOM   1199 C CD     . LYS   E 1 36  ? 293.004 225.146 208.851 1.00 34.86  ? 48  LYS   B CD     1 
ATOM   1200 C CE     . LYS   E 1 36  ? 293.063 224.426 210.181 1.00 37.57  ? 48  LYS   B CE     1 
ATOM   1201 N NZ     . LYS   E 1 36  ? 292.899 225.368 211.319 1.00 40.41  ? 48  LYS   B NZ     1 
ATOM   1202 N N      . LEU   E 1 37  ? 289.975 230.077 206.626 1.00 40.04  ? 49  LEU   B N      1 
ATOM   1203 C CA     . LEU   E 1 37  ? 289.813 231.035 205.542 1.00 42.05  ? 49  LEU   B CA     1 
ATOM   1204 C C      . LEU   E 1 37  ? 290.423 232.370 205.945 1.00 43.73  ? 49  LEU   B C      1 
ATOM   1205 O O      . LEU   E 1 37  ? 290.205 232.845 207.064 1.00 44.11  ? 49  LEU   B O      1 
ATOM   1206 C CB     . LEU   E 1 37  ? 288.337 231.219 205.184 1.00 41.64  ? 49  LEU   B CB     1 
ATOM   1207 C CG     . LEU   E 1 37  ? 287.565 229.992 204.703 1.00 41.26  ? 49  LEU   B CG     1 
ATOM   1208 C CD1    . LEU   E 1 37  ? 286.080 230.170 204.956 1.00 39.72  ? 49  LEU   B CD1    1 
ATOM   1209 C CD2    . LEU   E 1 37  ? 287.830 229.731 203.234 1.00 44.29  ? 49  LEU   B CD2    1 
ATOM   1210 N N      . SER   E 1 38  ? 291.176 232.974 205.030 1.00 44.42  ? 50  SER   B N      1 
ATOM   1211 C CA     . SER   E 1 38  ? 291.814 234.258 205.284 1.00 44.10  ? 50  SER   B CA     1 
ATOM   1212 C C      . SER   E 1 38  ? 290.777 235.373 205.175 1.00 48.11  ? 50  SER   B C      1 
ATOM   1213 O O      . SER   E 1 38  ? 289.592 235.133 204.928 1.00 53.77  ? 50  SER   B O      1 
ATOM   1214 C CB     . SER   E 1 38  ? 292.981 234.462 204.325 1.00 46.56  ? 50  SER   B CB     1 
ATOM   1215 O OG     . SER   E 1 38  ? 292.515 234.723 203.014 1.00 52.58  ? 50  SER   B OG     1 
ATOM   1216 N N      . ASP   E 1 39  ? 291.215 236.619 205.362 1.00 44.12  ? 51  ASP   B N      1 
ATOM   1217 C CA     . ASP   E 1 39  ? 290.283 237.741 205.325 1.00 46.45  ? 51  ASP   B CA     1 
ATOM   1218 C C      . ASP   E 1 39  ? 289.646 237.886 203.950 1.00 48.31  ? 51  ASP   B C      1 
ATOM   1219 O O      . ASP   E 1 39  ? 288.433 238.094 203.837 1.00 50.67  ? 51  ASP   B O      1 
ATOM   1220 C CB     . ASP   E 1 39  ? 290.996 239.031 205.727 1.00 47.93  ? 51  ASP   B CB     1 
ATOM   1221 C CG     . ASP   E 1 39  ? 290.158 239.895 206.641 1.00 55.26  ? 51  ASP   B CG     1 
ATOM   1222 O OD1    . ASP   E 1 39  ? 289.470 239.336 207.519 1.00 58.62  ? 51  ASP   B OD1    1 
ATOM   1223 O OD2    . ASP   E 1 39  ? 290.181 241.132 206.480 1.00 58.26  ? 51  ASP   B OD2    1 
ATOM   1224 N N      . TYR   E 1 40  ? 290.448 237.781 202.890 1.00 45.50  ? 52  TYR   B N      1 
ATOM   1225 C CA     . TYR   E 1 40  ? 289.897 237.890 201.544 1.00 43.90  ? 52  TYR   B CA     1 
ATOM   1226 C C      . TYR   E 1 40  ? 288.890 236.783 201.265 1.00 45.64  ? 52  TYR   B C      1 
ATOM   1227 O O      . TYR   E 1 40  ? 287.794 237.048 200.758 1.00 46.86  ? 52  TYR   B O      1 
ATOM   1228 C CB     . TYR   E 1 40  ? 291.023 237.862 200.513 1.00 45.95  ? 52  TYR   B CB     1 
ATOM   1229 C CG     . TYR   E 1 40  ? 290.668 238.527 199.207 1.00 48.57  ? 52  TYR   B CG     1 
ATOM   1230 C CD1    . TYR   E 1 40  ? 291.003 239.849 198.963 1.00 50.50  ? 52  TYR   B CD1    1 
ATOM   1231 C CD2    . TYR   E 1 40  ? 290.000 237.829 198.214 1.00 47.46  ? 52  TYR   B CD2    1 
ATOM   1232 C CE1    . TYR   E 1 40  ? 290.679 240.456 197.769 1.00 54.47  ? 52  TYR   B CE1    1 
ATOM   1233 C CE2    . TYR   E 1 40  ? 289.673 238.425 197.018 1.00 47.87  ? 52  TYR   B CE2    1 
ATOM   1234 C CZ     . TYR   E 1 40  ? 290.013 239.738 196.800 1.00 55.52  ? 52  TYR   B CZ     1 
ATOM   1235 O OH     . TYR   E 1 40  ? 289.688 240.337 195.606 1.00 63.95  ? 52  TYR   B OH     1 
ATOM   1236 N N      . GLU   E 1 41  ? 289.237 235.539 201.593 1.00 44.20  ? 53  GLU   B N      1 
ATOM   1237 C CA     . GLU   E 1 41  ? 288.332 234.428 201.323 1.00 41.47  ? 53  GLU   B CA     1 
ATOM   1238 C C      . GLU   E 1 41  ? 287.123 234.465 202.248 1.00 40.81  ? 53  GLU   B C      1 
ATOM   1239 O O      . GLU   E 1 41  ? 286.030 234.030 201.869 1.00 41.72  ? 53  GLU   B O      1 
ATOM   1240 C CB     . GLU   E 1 41  ? 289.082 233.105 201.455 1.00 41.83  ? 53  GLU   B CB     1 
ATOM   1241 C CG     . GLU   E 1 41  ? 290.524 233.190 200.996 1.00 42.76  ? 53  GLU   B CG     1 
ATOM   1242 C CD     . GLU   E 1 41  ? 291.399 232.124 201.611 1.00 48.17  ? 53  GLU   B CD     1 
ATOM   1243 O OE1    . GLU   E 1 41  ? 291.138 230.927 201.370 1.00 53.14  ? 53  GLU   B OE1    1 
ATOM   1244 O OE2    . GLU   E 1 41  ? 292.346 232.483 202.338 1.00 47.81  ? 53  GLU   B OE2    1 
ATOM   1245 N N      . GLY   E 1 42  ? 287.300 234.977 203.465 1.00 40.91  ? 54  GLY   B N      1 
ATOM   1246 C CA     . GLY   E 1 42  ? 286.168 235.124 204.363 1.00 39.99  ? 54  GLY   B CA     1 
ATOM   1247 C C      . GLY   E 1 42  ? 285.144 236.115 203.847 1.00 40.81  ? 54  GLY   B C      1 
ATOM   1248 O O      . GLY   E 1 42  ? 283.947 235.980 204.112 1.00 42.40  ? 54  GLY   B O      1 
ATOM   1249 N N      . ARG   E 1 43  ? 285.597 237.125 203.111 1.00 42.28  ? 55  ARG   B N      1 
ATOM   1250 C CA     . ARG   E 1 43  ? 284.721 238.148 202.560 1.00 40.77  ? 55  ARG   B CA     1 
ATOM   1251 C C      . ARG   E 1 43  ? 284.203 237.802 201.170 1.00 43.49  ? 55  ARG   B C      1 
ATOM   1252 O O      . ARG   E 1 43  ? 283.489 238.613 200.572 1.00 47.55  ? 55  ARG   B O      1 
ATOM   1253 C CB     . ARG   E 1 43  ? 285.451 239.494 202.526 1.00 40.18  ? 55  ARG   B CB     1 
ATOM   1254 C CG     . ARG   E 1 43  ? 285.765 240.045 203.906 1.00 42.73  ? 55  ARG   B CG     1 
ATOM   1255 C CD     . ARG   E 1 43  ? 286.719 241.219 203.838 1.00 45.90  ? 55  ARG   B CD     1 
ATOM   1256 N NE     . ARG   E 1 43  ? 287.014 241.756 205.161 1.00 44.51  ? 55  ARG   B NE     1 
ATOM   1257 C CZ     . ARG   E 1 43  ? 286.221 242.577 205.833 1.00 46.08  ? 55  ARG   B CZ     1 
ATOM   1258 N NH1    . ARG   E 1 43  ? 285.063 242.979 205.337 1.00 50.64  ? 55  ARG   B NH1    1 
ATOM   1259 N NH2    . ARG   E 1 43  ? 286.598 243.004 207.034 1.00 47.04  ? 55  ARG   B NH2    1 
ATOM   1260 N N      . LEU   E 1 44  ? 284.548 236.631 200.642 1.00 42.42  ? 56  LEU   B N      1 
ATOM   1261 C CA     . LEU   E 1 44  ? 284.032 236.208 199.347 1.00 39.95  ? 56  LEU   B CA     1 
ATOM   1262 C C      . LEU   E 1 44  ? 282.565 235.814 199.465 1.00 39.48  ? 56  LEU   B C      1 
ATOM   1263 O O      . LEU   E 1 44  ? 282.186 235.039 200.348 1.00 38.16  ? 56  LEU   B O      1 
ATOM   1264 C CB     . LEU   E 1 44  ? 284.849 235.038 198.806 1.00 38.13  ? 56  LEU   B CB     1 
ATOM   1265 C CG     . LEU   E 1 44  ? 284.872 234.877 197.286 1.00 35.97  ? 56  LEU   B CG     1 
ATOM   1266 C CD1    . LEU   E 1 44  ? 285.773 235.916 196.648 1.00 42.74  ? 56  LEU   B CD1    1 
ATOM   1267 C CD2    . LEU   E 1 44  ? 285.309 233.477 196.904 1.00 38.41  ? 56  LEU   B CD2    1 
ATOM   1268 N N      . ILE   E 1 45  ? 281.740 236.340 198.559 1.00 41.01  ? 57  ILE   B N      1 
ATOM   1269 C CA     . ILE   E 1 45  ? 280.314 236.040 198.604 1.00 41.13  ? 57  ILE   B CA     1 
ATOM   1270 C C      . ILE   E 1 45  ? 280.059 234.570 198.296 1.00 36.59  ? 57  ILE   B C      1 
ATOM   1271 O O      . ILE   E 1 45  ? 279.134 233.965 198.851 1.00 34.98  ? 57  ILE   B O      1 
ATOM   1272 C CB     . ILE   E 1 45  ? 279.544 236.967 197.646 1.00 40.08  ? 57  ILE   B CB     1 
ATOM   1273 C CG1    . ILE   E 1 45  ? 278.089 237.103 198.094 1.00 37.41  ? 57  ILE   B CG1    1 
ATOM   1274 C CG2    . ILE   E 1 45  ? 279.622 236.452 196.221 1.00 42.43  ? 57  ILE   B CG2    1 
ATOM   1275 C CD1    . ILE   E 1 45  ? 277.314 238.142 197.328 1.00 40.15  ? 57  ILE   B CD1    1 
ATOM   1276 N N      . GLN   E 1 46  ? 280.865 233.971 197.417 1.00 38.59  ? 58  GLN   B N      1 
ATOM   1277 C CA     . GLN   E 1 46  ? 280.696 232.556 197.105 1.00 39.40  ? 58  GLN   B CA     1 
ATOM   1278 C C      . GLN   E 1 46  ? 280.946 231.684 198.330 1.00 39.90  ? 58  GLN   B C      1 
ATOM   1279 O O      . GLN   E 1 46  ? 280.206 230.725 198.575 1.00 39.28  ? 58  GLN   B O      1 
ATOM   1280 C CB     . GLN   E 1 46  ? 281.624 232.157 195.960 1.00 41.25  ? 58  GLN   B CB     1 
ATOM   1281 C CG     . GLN   E 1 46  ? 281.064 232.438 194.576 1.00 37.50  ? 58  GLN   B CG     1 
ATOM   1282 C CD     . GLN   E 1 46  ? 281.025 233.915 194.251 1.00 36.93  ? 58  GLN   B CD     1 
ATOM   1283 O OE1    . GLN   E 1 46  ? 281.763 234.708 194.832 1.00 41.87  ? 58  GLN   B OE1    1 
ATOM   1284 N NE2    . GLN   E 1 46  ? 280.163 234.293 193.319 1.00 39.83  ? 58  GLN   B NE2    1 
ATOM   1285 N N      . ASN   E 1 47  ? 281.985 231.996 199.108 1.00 41.04  ? 59  ASN   B N      1 
ATOM   1286 C CA     . ASN   E 1 47  ? 282.254 231.232 200.323 1.00 39.21  ? 59  ASN   B CA     1 
ATOM   1287 C C      . ASN   E 1 47  ? 281.127 231.382 201.335 1.00 40.15  ? 59  ASN   B C      1 
ATOM   1288 O O      . ASN   E 1 47  ? 280.747 230.411 202.000 1.00 41.73  ? 59  ASN   B O      1 
ATOM   1289 C CB     . ASN   E 1 47  ? 283.587 231.662 200.936 1.00 39.34  ? 59  ASN   B CB     1 
ATOM   1290 C CG     . ASN   E 1 47  ? 284.777 231.194 200.126 1.00 41.85  ? 59  ASN   B CG     1 
ATOM   1291 O OD1    . ASN   E 1 47  ? 284.629 230.467 199.147 1.00 45.55  ? 59  ASN   B OD1    1 
ATOM   1292 N ND2    . ASN   E 1 47  ? 285.968 231.611 200.533 1.00 42.84  ? 59  ASN   B ND2    1 
ATOM   1293 N N      . SER   E 1 48  ? 280.587 232.594 201.479 1.00 39.40  ? 60  SER   B N      1 
ATOM   1294 C CA     . SER   E 1 48  ? 279.476 232.795 202.403 1.00 39.87  ? 60  SER   B CA     1 
ATOM   1295 C C      . SER   E 1 48  ? 278.252 232.000 201.967 1.00 37.86  ? 60  SER   B C      1 
ATOM   1296 O O      . SER   E 1 48  ? 277.534 231.442 202.804 1.00 40.11  ? 60  SER   B O      1 
ATOM   1297 C CB     . SER   E 1 48  ? 279.142 234.282 202.516 1.00 40.57  ? 60  SER   B CB     1 
ATOM   1298 O OG     . SER   E 1 48  ? 278.521 234.757 201.338 1.00 43.58  ? 60  SER   B OG     1 
ATOM   1299 N N      . LEU   E 1 49  ? 278.000 231.937 200.658 1.00 37.81  ? 61  LEU   B N      1 
ATOM   1300 C CA     . LEU   E 1 49  ? 276.875 231.155 200.157 1.00 38.19  ? 61  LEU   B CA     1 
ATOM   1301 C C      . LEU   E 1 49  ? 277.007 229.688 200.547 1.00 38.81  ? 61  LEU   B C      1 
ATOM   1302 O O      . LEU   E 1 49  ? 276.035 229.064 200.987 1.00 40.26  ? 61  LEU   B O      1 
ATOM   1303 C CB     . LEU   E 1 49  ? 276.777 231.298 198.638 1.00 39.61  ? 61  LEU   B CB     1 
ATOM   1304 C CG     . LEU   E 1 49  ? 275.723 232.257 198.083 1.00 36.98  ? 61  LEU   B CG     1 
ATOM   1305 C CD1    . LEU   E 1 49  ? 274.330 231.824 198.498 1.00 40.44  ? 61  LEU   B CD1    1 
ATOM   1306 C CD2    . LEU   E 1 49  ? 275.999 233.678 198.531 1.00 39.36  ? 61  LEU   B CD2    1 
ATOM   1307 N N      . THR   E 1 50  ? 278.205 229.121 200.395 1.00 38.90  ? 62  THR   B N      1 
ATOM   1308 C CA     . THR   E 1 50  ? 278.412 227.723 200.757 1.00 38.39  ? 62  THR   B CA     1 
ATOM   1309 C C      . THR   E 1 50  ? 278.175 227.496 202.244 1.00 38.52  ? 62  THR   B C      1 
ATOM   1310 O O      . THR   E 1 50  ? 277.526 226.520 202.636 1.00 40.94  ? 62  THR   B O      1 
ATOM   1311 C CB     . THR   E 1 50  ? 279.825 227.285 200.372 1.00 41.20  ? 62  THR   B CB     1 
ATOM   1312 O OG1    . THR   E 1 50  ? 279.874 227.000 198.969 1.00 43.95  ? 62  THR   B OG1    1 
ATOM   1313 C CG2    . THR   E 1 50  ? 280.224 226.045 201.149 1.00 43.90  ? 62  THR   B CG2    1 
ATOM   1314 N N      . ILE   E 1 51  ? 278.691 228.391 203.087 1.00 38.25  ? 63  ILE   B N      1 
ATOM   1315 C CA     . ILE   E 1 51  ? 278.525 228.238 204.529 1.00 39.34  ? 63  ILE   B CA     1 
ATOM   1316 C C      . ILE   E 1 51  ? 277.052 228.330 204.908 1.00 40.73  ? 63  ILE   B C      1 
ATOM   1317 O O      . ILE   E 1 51  ? 276.555 227.558 205.735 1.00 42.50  ? 63  ILE   B O      1 
ATOM   1318 C CB     . ILE   E 1 51  ? 279.370 229.282 205.279 1.00 40.40  ? 63  ILE   B CB     1 
ATOM   1319 C CG1    . ILE   E 1 51  ? 280.859 229.008 205.065 1.00 43.29  ? 63  ILE   B CG1    1 
ATOM   1320 C CG2    . ILE   E 1 51  ? 279.033 229.278 206.757 1.00 44.14  ? 63  ILE   B CG2    1 
ATOM   1321 C CD1    . ILE   E 1 51  ? 281.761 229.876 205.903 1.00 45.50  ? 63  ILE   B CD1    1 
ATOM   1322 N N      . GLU   E 1 52  ? 276.334 229.284 204.312 1.00 38.49  ? 64  GLU   B N      1 
ATOM   1323 C CA     . GLU   E 1 52  ? 274.915 229.434 204.615 1.00 37.17  ? 64  GLU   B CA     1 
ATOM   1324 C C      . GLU   E 1 52  ? 274.124 228.202 204.191 1.00 39.06  ? 64  GLU   B C      1 
ATOM   1325 O O      . GLU   E 1 52  ? 273.254 227.730 204.931 1.00 42.74  ? 64  GLU   B O      1 
ATOM   1326 C CB     . GLU   E 1 52  ? 274.363 230.683 203.932 1.00 37.56  ? 64  GLU   B CB     1 
ATOM   1327 C CG     . GLU   E 1 52  ? 275.019 231.971 204.379 1.00 38.46  ? 64  GLU   B CG     1 
ATOM   1328 C CD     . GLU   E 1 52  ? 274.758 233.111 203.422 1.00 44.81  ? 64  GLU   B CD     1 
ATOM   1329 O OE1    . GLU   E 1 52  ? 274.183 232.861 202.344 1.00 48.71  ? 64  GLU   B OE1    1 
ATOM   1330 O OE2    . GLU   E 1 52  ? 275.123 234.258 203.746 1.00 46.52  ? 64  GLU   B OE2    1 
ATOM   1331 N N      . ARG   E 1 53  ? 274.410 227.669 203.002 1.00 38.24  ? 65  ARG   B N      1 
ATOM   1332 C CA     . ARG   E 1 53  ? 273.688 226.494 202.529 1.00 38.99  ? 65  ARG   B CA     1 
ATOM   1333 C C      . ARG   E 1 53  ? 273.987 225.273 203.388 1.00 41.44  ? 65  ARG   B C      1 
ATOM   1334 O O      . ARG   E 1 53  ? 273.102 224.438 203.607 1.00 41.12  ? 65  ARG   B O      1 
ATOM   1335 C CB     . ARG   E 1 53  ? 274.029 226.226 201.063 1.00 36.15  ? 65  ARG   B CB     1 
ATOM   1336 C CG     . ARG   E 1 53  ? 273.727 227.406 200.155 1.00 41.10  ? 65  ARG   B CG     1 
ATOM   1337 C CD     . ARG   E 1 53  ? 274.077 227.134 198.702 1.00 42.40  ? 65  ARG   B CD     1 
ATOM   1338 N NE     . ARG   E 1 53  ? 272.943 226.615 197.949 1.00 39.91  ? 65  ARG   B NE     1 
ATOM   1339 C CZ     . ARG   E 1 53  ? 272.976 225.516 197.208 1.00 47.21  ? 65  ARG   B CZ     1 
ATOM   1340 N NH1    . ARG   E 1 53  ? 274.082 224.803 197.080 1.00 50.11  ? 65  ARG   B NH1    1 
ATOM   1341 N NH2    . ARG   E 1 53  ? 271.873 225.125 196.579 1.00 50.88  ? 65  ARG   B NH2    1 
ATOM   1342 N N      . MET   E 1 54  ? 275.219 225.154 203.886 1.00 40.19  ? 66  MET   B N      1 
ATOM   1343 C CA     . MET   E 1 54  ? 275.555 224.050 204.779 1.00 39.39  ? 66  MET   B CA     1 
ATOM   1344 C C      . MET   E 1 54  ? 274.698 224.087 206.036 1.00 39.52  ? 66  MET   B C      1 
ATOM   1345 O O      . MET   E 1 54  ? 274.237 223.046 206.517 1.00 41.13  ? 66  MET   B O      1 
ATOM   1346 C CB     . MET   E 1 54  ? 277.041 224.100 205.141 1.00 37.05  ? 66  MET   B CB     1 
ATOM   1347 C CG     . MET   E 1 54  ? 277.931 223.255 204.249 1.00 41.52  ? 66  MET   B CG     1 
ATOM   1348 S SD     . MET   E 1 54  ? 279.571 222.982 204.947 1.00 52.42  ? 66  MET   B SD     1 
ATOM   1349 C CE     . MET   E 1 54  ? 280.209 224.650 205.004 1.00 41.73  ? 66  MET   B CE     1 
ATOM   1350 N N      . VAL   E 1 55  ? 274.479 225.282 206.585 1.00 39.57  ? 67  VAL   B N      1 
ATOM   1351 C CA     . VAL   E 1 55  ? 273.647 225.419 207.775 1.00 39.27  ? 67  VAL   B CA     1 
ATOM   1352 C C      . VAL   E 1 55  ? 272.213 225.009 207.476 1.00 40.78  ? 67  VAL   B C      1 
ATOM   1353 O O      . VAL   E 1 55  ? 271.591 224.265 208.242 1.00 44.15  ? 67  VAL   B O      1 
ATOM   1354 C CB     . VAL   E 1 55  ? 273.713 226.864 208.294 1.00 41.84  ? 67  VAL   B CB     1 
ATOM   1355 C CG1    . VAL   E 1 55  ? 272.936 227.003 209.591 1.00 43.24  ? 67  VAL   B CG1    1 
ATOM   1356 C CG2    . VAL   E 1 55  ? 275.141 227.289 208.450 1.00 45.75  ? 67  VAL   B CG2    1 
ATOM   1357 N N      . LEU   E 1 56  ? 271.665 225.493 206.361 1.00 38.68  ? 68  LEU   B N      1 
ATOM   1358 C CA     . LEU   E 1 56  ? 270.270 225.217 206.043 1.00 41.74  ? 68  LEU   B CA     1 
ATOM   1359 C C      . LEU   E 1 56  ? 270.036 223.727 205.839 1.00 43.80  ? 68  LEU   B C      1 
ATOM   1360 O O      . LEU   E 1 56  ? 269.020 223.184 206.287 1.00 46.78  ? 68  LEU   B O      1 
ATOM   1361 C CB     . LEU   E 1 56  ? 269.854 226.011 204.807 1.00 41.63  ? 68  LEU   B CB     1 
ATOM   1362 C CG     . LEU   E 1 56  ? 269.925 227.532 204.947 1.00 39.19  ? 68  LEU   B CG     1 
ATOM   1363 C CD1    . LEU   E 1 56  ? 269.433 228.207 203.681 1.00 39.07  ? 68  LEU   B CD1    1 
ATOM   1364 C CD2    . LEU   E 1 56  ? 269.120 227.996 206.146 1.00 39.85  ? 68  LEU   B CD2    1 
ATOM   1365 N N      . SER   E 1 57  ? 270.964 223.047 205.164 1.00 42.24  ? 69  SER   B N      1 
ATOM   1366 C CA     . SER   E 1 57  ? 270.831 221.608 204.983 1.00 42.45  ? 69  SER   B CA     1 
ATOM   1367 C C      . SER   E 1 57  ? 271.008 220.847 206.289 1.00 42.24  ? 69  SER   B C      1 
ATOM   1368 O O      . SER   E 1 57  ? 270.364 219.810 206.478 1.00 45.05  ? 69  SER   B O      1 
ATOM   1369 C CB     . SER   E 1 57  ? 271.841 221.110 203.949 1.00 40.41  ? 69  SER   B CB     1 
ATOM   1370 O OG     . SER   E 1 57  ? 273.098 220.855 204.546 1.00 46.52  ? 69  SER   B OG     1 
ATOM   1371 N N      . ALA   E 1 58  ? 271.856 221.338 207.194 1.00 38.95  ? 70  ALA   B N      1 
ATOM   1372 C CA     . ALA   E 1 58  ? 272.052 220.651 208.465 1.00 40.67  ? 70  ALA   B CA     1 
ATOM   1373 C C      . ALA   E 1 58  ? 270.798 220.692 209.329 1.00 42.60  ? 70  ALA   B C      1 
ATOM   1374 O O      . ALA   E 1 58  ? 270.580 219.788 210.142 1.00 46.13  ? 70  ALA   B O      1 
ATOM   1375 C CB     . ALA   E 1 58  ? 273.234 221.261 209.216 1.00 40.71  ? 70  ALA   B CB     1 
ATOM   1376 N N      . PHE   E 1 59  ? 269.967 221.719 209.171 1.00 42.14  ? 71  PHE   B N      1 
ATOM   1377 C CA     . PHE   E 1 59  ? 268.744 221.861 209.949 1.00 41.57  ? 71  PHE   B CA     1 
ATOM   1378 C C      . PHE   E 1 59  ? 267.502 221.430 209.181 1.00 46.20  ? 71  PHE   B C      1 
ATOM   1379 O O      . PHE   E 1 59  ? 266.385 221.672 209.647 1.00 53.12  ? 71  PHE   B O      1 
ATOM   1380 C CB     . PHE   E 1 59  ? 268.591 223.302 210.432 1.00 38.52  ? 71  PHE   B CB     1 
ATOM   1381 C CG     . PHE   E 1 59  ? 269.455 223.633 211.609 1.00 38.71  ? 71  PHE   B CG     1 
ATOM   1382 C CD1    . PHE   E 1 59  ? 268.988 223.455 212.897 1.00 40.78  ? 71  PHE   B CD1    1 
ATOM   1383 C CD2    . PHE   E 1 59  ? 270.741 224.106 211.429 1.00 36.99  ? 71  PHE   B CD2    1 
ATOM   1384 C CE1    . PHE   E 1 59  ? 269.783 223.753 213.984 1.00 39.05  ? 71  PHE   B CE1    1 
ATOM   1385 C CE2    . PHE   E 1 59  ? 271.538 224.404 212.512 1.00 38.59  ? 71  PHE   B CE2    1 
ATOM   1386 C CZ     . PHE   E 1 59  ? 271.058 224.225 213.791 1.00 37.74  ? 71  PHE   B CZ     1 
ATOM   1387 N N      . ASP   E 1 60  ? 267.668 220.800 208.022 1.00 45.60  ? 72  ASP   B N      1 
ATOM   1388 C CA     . ASP   E 1 60  ? 266.543 220.279 207.247 1.00 45.53  ? 72  ASP   B CA     1 
ATOM   1389 C C      . ASP   E 1 60  ? 266.184 218.908 207.803 1.00 47.74  ? 72  ASP   B C      1 
ATOM   1390 O O      . ASP   E 1 60  ? 266.670 217.876 207.341 1.00 49.47  ? 72  ASP   B O      1 
ATOM   1391 C CB     . ASP   E 1 60  ? 266.895 220.208 205.768 1.00 44.66  ? 72  ASP   B CB     1 
ATOM   1392 C CG     . ASP   E 1 60  ? 265.672 220.205 204.881 1.00 48.61  ? 72  ASP   B CG     1 
ATOM   1393 O OD1    . ASP   E 1 60  ? 264.588 219.825 205.365 1.00 48.65  ? 72  ASP   B OD1    1 
ATOM   1394 O OD2    . ASP   E 1 60  ? 265.797 220.582 203.698 1.00 51.23  ? 72  ASP   B OD2    1 
ATOM   1395 N N      . GLU   E 1 61  ? 265.319 218.898 208.817 1.00 46.81  ? 73  GLU   B N      1 
ATOM   1396 C CA     . GLU   E 1 61  ? 264.978 217.644 209.479 1.00 48.46  ? 73  GLU   B CA     1 
ATOM   1397 C C      . GLU   E 1 61  ? 264.291 216.673 208.526 1.00 47.97  ? 73  GLU   B C      1 
ATOM   1398 O O      . GLU   E 1 61  ? 264.630 215.484 208.491 1.00 49.95  ? 73  GLU   B O      1 
ATOM   1399 C CB     . GLU   E 1 61  ? 264.094 217.921 210.692 1.00 52.70  ? 73  GLU   B CB     1 
ATOM   1400 C CG     . GLU   E 1 61  ? 263.592 216.674 211.384 1.00 56.92  ? 73  GLU   B CG     1 
ATOM   1401 C CD     . GLU   E 1 61  ? 263.594 216.809 212.888 1.00 71.28  ? 73  GLU   B CD     1 
ATOM   1402 O OE1    . GLU   E 1 61  ? 263.069 217.822 213.392 1.00 74.58  ? 73  GLU   B OE1    1 
ATOM   1403 O OE2    . GLU   E 1 61  ? 264.118 215.903 213.566 1.00 84.87  ? 73  GLU   B OE2    1 
ATOM   1404 N N      . ARG   E 1 62  ? 263.323 217.156 207.744 1.00 45.55  ? 74  ARG   B N      1 
ATOM   1405 C CA     . ARG   E 1 62  ? 262.563 216.262 206.875 1.00 44.46  ? 74  ARG   B CA     1 
ATOM   1406 C C      . ARG   E 1 62  ? 263.438 215.668 205.779 1.00 45.43  ? 74  ARG   B C      1 
ATOM   1407 O O      . ARG   E 1 62  ? 263.441 214.450 205.569 1.00 48.01  ? 74  ARG   B O      1 
ATOM   1408 C CB     . ARG   E 1 62  ? 261.374 217.000 206.262 1.00 45.28  ? 74  ARG   B CB     1 
ATOM   1409 C CG     . ARG   E 1 62  ? 260.231 217.226 207.221 1.00 47.02  ? 74  ARG   B CG     1 
ATOM   1410 C CD     . ARG   E 1 62  ? 258.938 216.667 206.658 1.00 49.08  ? 74  ARG   B CD     1 
ATOM   1411 N NE     . ARG   E 1 62  ? 258.521 217.349 205.441 1.00 48.99  ? 74  ARG   B NE     1 
ATOM   1412 C CZ     . ARG   E 1 62  ? 257.259 217.487 205.061 1.00 51.90  ? 74  ARG   B CZ     1 
ATOM   1413 N NH1    . ARG   E 1 62  ? 256.264 216.997 205.780 1.00 45.11  ? 74  ARG   B NH1    1 
ATOM   1414 N NH2    . ARG   E 1 62  ? 256.988 218.135 203.932 1.00 59.45  ? 74  ARG   B NH2    1 
ATOM   1415 N N      . ARG   E 1 63  ? 264.183 216.511 205.064 1.00 43.66  ? 75  ARG   B N      1 
ATOM   1416 C CA     . ARG   E 1 63  ? 265.016 216.000 203.981 1.00 42.87  ? 75  ARG   B CA     1 
ATOM   1417 C C      . ARG   E 1 63  ? 266.084 215.056 204.512 1.00 43.59  ? 75  ARG   B C      1 
ATOM   1418 O O      . ARG   E 1 63  ? 266.354 214.010 203.912 1.00 46.09  ? 75  ARG   B O      1 
ATOM   1419 C CB     . ARG   E 1 63  ? 265.653 217.154 203.210 1.00 42.61  ? 75  ARG   B CB     1 
ATOM   1420 C CG     . ARG   E 1 63  ? 266.899 216.759 202.441 1.00 43.41  ? 75  ARG   B CG     1 
ATOM   1421 C CD     . ARG   E 1 63  ? 267.469 217.926 201.661 1.00 42.29  ? 75  ARG   B CD     1 
ATOM   1422 N NE     . ARG   E 1 63  ? 268.741 217.586 201.037 1.00 44.25  ? 75  ARG   B NE     1 
ATOM   1423 C CZ     . ARG   E 1 63  ? 268.866 216.849 199.943 1.00 47.56  ? 75  ARG   B CZ     1 
ATOM   1424 N NH1    . ARG   E 1 63  ? 267.811 216.348 199.322 1.00 38.01  ? 75  ARG   B NH1    1 
ATOM   1425 N NH2    . ARG   E 1 63  ? 270.081 216.605 199.461 1.00 54.91  ? 75  ARG   B NH2    1 
ATOM   1426 N N      . ASN   E 1 64  ? 266.695 215.404 205.645 1.00 42.54  ? 76  ASN   B N      1 
ATOM   1427 C CA     . ASN   E 1 64  ? 267.717 214.539 206.223 1.00 42.08  ? 76  ASN   B CA     1 
ATOM   1428 C C      . ASN   E 1 64  ? 267.144 213.170 206.563 1.00 41.34  ? 76  ASN   B C      1 
ATOM   1429 O O      . ASN   E 1 64  ? 267.790 212.144 206.327 1.00 42.04  ? 76  ASN   B O      1 
ATOM   1430 C CB     . ASN   E 1 64  ? 268.317 215.199 207.463 1.00 42.82  ? 76  ASN   B CB     1 
ATOM   1431 C CG     . ASN   E 1 64  ? 269.158 216.413 207.126 1.00 41.96  ? 76  ASN   B CG     1 
ATOM   1432 O OD1    . ASN   E 1 64  ? 269.320 216.768 205.960 1.00 41.16  ? 76  ASN   B OD1    1 
ATOM   1433 N ND2    . ASN   E 1 64  ? 269.695 217.061 208.150 1.00 43.95  ? 76  ASN   B ND2    1 
ATOM   1434 N N      . LYS   E 1 65  ? 265.928 213.135 207.112 1.00 43.27  ? 77  LYS   B N      1 
ATOM   1435 C CA     . LYS   E 1 65  ? 265.281 211.859 207.399 1.00 43.44  ? 77  LYS   B CA     1 
ATOM   1436 C C      . LYS   E 1 65  ? 265.066 211.051 206.128 1.00 44.00  ? 77  LYS   B C      1 
ATOM   1437 O O      . LYS   E 1 65  ? 265.315 209.841 206.103 1.00 44.49  ? 77  LYS   B O      1 
ATOM   1438 C CB     . LYS   E 1 65  ? 263.949 212.091 208.109 1.00 43.06  ? 77  LYS   B CB     1 
ATOM   1439 C CG     . LYS   E 1 65  ? 264.050 212.180 209.615 1.00 48.26  ? 77  LYS   B CG     1 
ATOM   1440 C CD     . LYS   E 1 65  ? 262.952 211.370 210.276 1.00 57.89  ? 77  LYS   B CD     1 
ATOM   1441 C CE     . LYS   E 1 65  ? 261.592 212.007 210.058 1.00 64.99  ? 77  LYS   B CE     1 
ATOM   1442 N NZ     . LYS   E 1 65  ? 260.769 211.996 211.296 1.00 71.89  ? 77  LYS   B NZ     1 
ATOM   1443 N N      . TYR   E 1 66  ? 264.599 211.702 205.061 1.00 42.08  ? 78  TYR   B N      1 
ATOM   1444 C CA     . TYR   E 1 66  ? 264.403 210.994 203.803 1.00 42.02  ? 78  TYR   B CA     1 
ATOM   1445 C C      . TYR   E 1 66  ? 265.724 210.459 203.269 1.00 45.13  ? 78  TYR   B C      1 
ATOM   1446 O O      . TYR   E 1 66  ? 265.792 209.328 202.773 1.00 47.42  ? 78  TYR   B O      1 
ATOM   1447 C CB     . TYR   E 1 66  ? 263.738 211.911 202.778 1.00 42.29  ? 78  TYR   B CB     1 
ATOM   1448 C CG     . TYR   E 1 66  ? 263.463 211.242 201.451 1.00 43.76  ? 78  TYR   B CG     1 
ATOM   1449 C CD1    . TYR   E 1 66  ? 262.253 210.611 201.209 1.00 44.19  ? 78  TYR   B CD1    1 
ATOM   1450 C CD2    . TYR   E 1 66  ? 264.413 211.244 200.439 1.00 43.70  ? 78  TYR   B CD2    1 
ATOM   1451 C CE1    . TYR   E 1 66  ? 261.998 210.000 200.000 1.00 47.26  ? 78  TYR   B CE1    1 
ATOM   1452 C CE2    . TYR   E 1 66  ? 264.167 210.635 199.228 1.00 45.06  ? 78  TYR   B CE2    1 
ATOM   1453 C CZ     . TYR   E 1 66  ? 262.959 210.014 199.014 1.00 52.47  ? 78  TYR   B CZ     1 
ATOM   1454 O OH     . TYR   E 1 66  ? 262.708 209.406 197.807 1.00 66.83  ? 78  TYR   B OH     1 
ATOM   1455 N N      . LEU   E 1 67  ? 266.790 211.255 203.371 1.00 44.07  ? 79  LEU   B N      1 
ATOM   1456 C CA     . LEU   E 1 67  ? 268.093 210.802 202.902 1.00 43.34  ? 79  LEU   B CA     1 
ATOM   1457 C C      . LEU   E 1 67  ? 268.564 209.579 203.678 1.00 45.39  ? 79  LEU   B C      1 
ATOM   1458 O O      . LEU   E 1 67  ? 269.121 208.644 203.094 1.00 49.78  ? 79  LEU   B O      1 
ATOM   1459 C CB     . LEU   E 1 67  ? 269.112 211.935 203.012 1.00 44.19  ? 79  LEU   B CB     1 
ATOM   1460 C CG     . LEU   E 1 67  ? 269.075 212.993 201.911 1.00 43.34  ? 79  LEU   B CG     1 
ATOM   1461 C CD1    . LEU   E 1 67  ? 270.287 213.898 202.008 1.00 44.68  ? 79  LEU   B CD1    1 
ATOM   1462 C CD2    . LEU   E 1 67  ? 269.005 212.338 200.546 1.00 46.76  ? 79  LEU   B CD2    1 
ATOM   1463 N N      . GLU   E 1 68  ? 268.350 209.568 204.996 1.00 45.18  ? 80  GLU   B N      1 
ATOM   1464 C CA     . GLU   E 1 68  ? 268.734 208.410 205.796 1.00 44.20  ? 80  GLU   B CA     1 
ATOM   1465 C C      . GLU   E 1 68  ? 267.997 207.159 205.336 1.00 43.98  ? 80  GLU   B C      1 
ATOM   1466 O O      . GLU   E 1 68  ? 268.606 206.099 205.153 1.00 41.48  ? 80  GLU   B O      1 
ATOM   1467 C CB     . GLU   E 1 68  ? 268.446 208.679 207.272 1.00 44.85  ? 80  GLU   B CB     1 
ATOM   1468 C CG     . GLU   E 1 68  ? 268.919 210.029 207.771 1.00 45.09  ? 80  GLU   B CG     1 
ATOM   1469 C CD     . GLU   E 1 68  ? 270.045 209.928 208.768 1.00 53.40  ? 80  GLU   B CD     1 
ATOM   1470 O OE1    . GLU   E 1 68  ? 270.630 208.833 208.898 1.00 62.27  ? 80  GLU   B OE1    1 
ATOM   1471 O OE2    . GLU   E 1 68  ? 270.343 210.945 209.427 1.00 52.69  ? 80  GLU   B OE2    1 
ATOM   1472 N N      . GLU   E 1 69  ? 266.681 207.265 205.147 1.00 47.25  ? 81  GLU   B N      1 
ATOM   1473 C CA     . GLU   E 1 69  ? 265.888 206.117 204.722 1.00 46.46  ? 81  GLU   B CA     1 
ATOM   1474 C C      . GLU   E 1 69  ? 266.267 205.669 203.318 1.00 47.48  ? 81  GLU   B C      1 
ATOM   1475 O O      . GLU   E 1 69  ? 266.404 204.468 203.058 1.00 50.26  ? 81  GLU   B O      1 
ATOM   1476 C CB     . GLU   E 1 69  ? 264.402 206.462 204.786 1.00 46.32  ? 81  GLU   B CB     1 
ATOM   1477 C CG     . GLU   E 1 69  ? 263.876 206.690 206.185 1.00 49.92  ? 81  GLU   B CG     1 
ATOM   1478 C CD     . GLU   E 1 69  ? 262.397 206.399 206.297 1.00 64.37  ? 81  GLU   B CD     1 
ATOM   1479 O OE1    . GLU   E 1 69  ? 262.009 205.222 206.149 1.00 71.80  ? 81  GLU   B OE1    1 
ATOM   1480 O OE2    . GLU   E 1 69  ? 261.621 207.347 206.532 1.00 68.20  ? 81  GLU   B OE2    1 
ATOM   1481 N N      . HIS   E 1 70  ? 266.446 206.617 202.403 1.00 45.11  ? 82  HIS   B N      1 
ATOM   1482 C CA     . HIS   E 1 70  ? 266.759 206.331 201.004 1.00 45.57  ? 82  HIS   B CA     1 
ATOM   1483 C C      . HIS   E 1 70  ? 268.037 207.078 200.656 1.00 47.47  ? 82  HIS   B C      1 
ATOM   1484 O O      . HIS   E 1 70  ? 267.999 208.132 200.007 1.00 48.23  ? 82  HIS   B O      1 
ATOM   1485 C CB     . HIS   E 1 70  ? 265.609 206.737 200.082 1.00 47.80  ? 82  HIS   B CB     1 
ATOM   1486 C CG     . HIS   E 1 70  ? 264.261 206.313 200.574 1.00 49.57  ? 82  HIS   B CG     1 
ATOM   1487 N ND1    . HIS   E 1 70  ? 263.126 207.069 200.377 1.00 52.28  ? 82  HIS   B ND1    1 
ATOM   1488 C CD2    . HIS   E 1 70  ? 263.863 205.206 201.244 1.00 52.68  ? 82  HIS   B CD2    1 
ATOM   1489 C CE1    . HIS   E 1 70  ? 262.089 206.451 200.913 1.00 52.02  ? 82  HIS   B CE1    1 
ATOM   1490 N NE2    . HIS   E 1 70  ? 262.509 205.318 201.444 1.00 53.24  ? 82  HIS   B NE2    1 
ATOM   1491 N N      . PRO   E 1 71  ? 269.188 206.562 201.073 1.00 47.40  ? 83  PRO   B N      1 
ATOM   1492 C CA     . PRO   E 1 71  ? 270.444 207.273 200.820 1.00 47.97  ? 83  PRO   B CA     1 
ATOM   1493 C C      . PRO   E 1 71  ? 270.723 207.404 199.334 1.00 49.47  ? 83  PRO   B C      1 
ATOM   1494 O O      . PRO   E 1 71  ? 270.369 206.541 198.528 1.00 49.10  ? 83  PRO   B O      1 
ATOM   1495 C CB     . PRO   E 1 71  ? 271.500 206.401 201.510 1.00 44.47  ? 83  PRO   B CB     1 
ATOM   1496 C CG     . PRO   E 1 71  ? 270.874 205.073 201.681 1.00 44.15  ? 83  PRO   B CG     1 
ATOM   1497 C CD     . PRO   E 1 71  ? 269.393 205.264 201.735 1.00 47.29  ? 83  PRO   B CD     1 
ATOM   1498 N N      . SER   E 1 72  ? 271.364 208.511 198.977 1.00 50.54  ? 84  SER   B N      1 
ATOM   1499 C CA     . SER   E 1 72  ? 271.768 208.751 197.601 1.00 53.74  ? 84  SER   B CA     1 
ATOM   1500 C C      . SER   E 1 72  ? 273.016 207.920 197.305 1.00 55.57  ? 84  SER   B C      1 
ATOM   1501 O O      . SER   E 1 72  ? 273.553 207.232 198.176 1.00 55.40  ? 84  SER   B O      1 
ATOM   1502 C CB     . SER   E 1 72  ? 271.984 210.244 197.368 1.00 57.74  ? 84  SER   B CB     1 
ATOM   1503 O OG     . SER   E 1 72  ? 272.184 210.523 195.994 1.00 68.69  ? 84  SER   B OG     1 
ATOM   1504 N N      . ALA   E 1 73  ? 273.498 207.978 196.068 1.00 58.90  ? 85  ALA   B N      1 
ATOM   1505 C CA     . ALA   E 1 73  ? 274.594 207.126 195.620 1.00 56.32  ? 85  ALA   B CA     1 
ATOM   1506 C C      . ALA   E 1 73  ? 275.918 207.829 195.889 1.00 57.63  ? 85  ALA   B C      1 
ATOM   1507 O O      . ALA   E 1 73  ? 276.226 208.850 195.267 1.00 59.66  ? 85  ALA   B O      1 
ATOM   1508 C CB     . ALA   E 1 73  ? 274.442 206.790 194.139 1.00 62.27  ? 85  ALA   B CB     1 
ATOM   1509 N N      . GLY   E 1 74  ? 276.703 207.276 196.811 1.00 54.81  ? 86  GLY   B N      1 
ATOM   1510 C CA     . GLY   E 1 74  ? 277.993 207.830 197.157 1.00 56.78  ? 86  GLY   B CA     1 
ATOM   1511 C C      . GLY   E 1 74  ? 277.954 209.010 198.099 1.00 62.14  ? 86  GLY   B C      1 
ATOM   1512 O O      . GLY   E 1 74  ? 279.015 209.567 198.409 1.00 68.17  ? 86  GLY   B O      1 
ATOM   1513 N N      . LYS   E 1 75  ? 276.775 209.411 198.566 1.00 58.70  ? 87  LYS   B N      1 
ATOM   1514 C CA     . LYS   E 1 75  ? 276.623 210.552 199.462 1.00 54.68  ? 87  LYS   B CA     1 
ATOM   1515 C C      . LYS   E 1 75  ? 275.915 210.074 200.720 1.00 54.37  ? 87  LYS   B C      1 
ATOM   1516 O O      . LYS   E 1 75  ? 274.723 209.754 200.677 1.00 59.26  ? 87  LYS   B O      1 
ATOM   1517 C CB     . LYS   E 1 75  ? 275.833 211.677 198.794 1.00 59.49  ? 87  LYS   B CB     1 
ATOM   1518 C CG     . LYS   E 1 75  ? 276.282 212.012 197.386 1.00 63.16  ? 87  LYS   B CG     1 
ATOM   1519 C CD     . LYS   E 1 75  ? 275.319 212.985 196.729 1.00 63.98  ? 87  LYS   B CD     1 
ATOM   1520 C CE     . LYS   E 1 75  ? 276.049 214.183 196.153 1.00 76.09  ? 87  LYS   B CE     1 
ATOM   1521 N NZ     . LYS   E 1 75  ? 276.799 213.831 194.919 1.00 86.98  ? 87  LYS   B NZ     1 
ATOM   1522 N N      . ASP   E 1 76  ? 276.636 210.022 201.832 1.00 50.90  ? 88  ASP   B N      1 
ATOM   1523 C CA     . ASP   E 1 76  ? 276.001 209.642 203.082 1.00 51.34  ? 88  ASP   B CA     1 
ATOM   1524 C C      . ASP   E 1 76  ? 275.122 210.786 203.582 1.00 48.04  ? 88  ASP   B C      1 
ATOM   1525 O O      . ASP   E 1 76  ? 275.512 211.954 203.498 1.00 45.29  ? 88  ASP   B O      1 
ATOM   1526 C CB     . ASP   E 1 76  ? 277.043 209.274 204.136 1.00 47.39  ? 88  ASP   B CB     1 
ATOM   1527 C CG     . ASP   E 1 76  ? 278.020 210.389 204.403 1.00 50.50  ? 88  ASP   B CG     1 
ATOM   1528 O OD1    . ASP   E 1 76  ? 278.325 211.149 203.461 1.00 57.97  ? 88  ASP   B OD1    1 
ATOM   1529 O OD2    . ASP   E 1 76  ? 278.488 210.502 205.553 1.00 47.49  ? 88  ASP   B OD2    1 
ATOM   1530 N N      . PRO   E 1 77  ? 273.935 210.485 204.108 1.00 46.60  ? 89  PRO   B N      1 
ATOM   1531 C CA     . PRO   E 1 77  ? 273.001 211.539 204.516 1.00 46.16  ? 89  PRO   B CA     1 
ATOM   1532 C C      . PRO   E 1 77  ? 273.351 212.226 205.826 1.00 47.71  ? 89  PRO   B C      1 
ATOM   1533 O O      . PRO   E 1 77  ? 272.504 212.937 206.372 1.00 49.01  ? 89  PRO   B O      1 
ATOM   1534 C CB     . PRO   E 1 77  ? 271.673 210.779 204.639 1.00 47.97  ? 89  PRO   B CB     1 
ATOM   1535 C CG     . PRO   E 1 77  ? 272.067 209.390 204.971 1.00 46.51  ? 89  PRO   B CG     1 
ATOM   1536 C CD     . PRO   E 1 77  ? 273.362 209.137 204.263 1.00 45.01  ? 89  PRO   B CD     1 
ATOM   1537 N N      . LYS   E 1 78  ? 274.561 212.040 206.346 1.00 46.51  ? 90  LYS   B N      1 
ATOM   1538 C CA     . LYS   E 1 78  ? 274.979 212.679 207.585 1.00 44.80  ? 90  LYS   B CA     1 
ATOM   1539 C C      . LYS   E 1 78  ? 276.003 213.785 207.369 1.00 43.28  ? 90  LYS   B C      1 
ATOM   1540 O O      . LYS   E 1 78  ? 276.376 214.458 208.335 1.00 43.68  ? 90  LYS   B O      1 
ATOM   1541 C CB     . LYS   E 1 78  ? 275.548 211.632 208.549 1.00 42.30  ? 90  LYS   B CB     1 
ATOM   1542 C CG     . LYS   E 1 78  ? 274.570 210.531 208.908 1.00 42.08  ? 90  LYS   B CG     1 
ATOM   1543 C CD     . LYS   E 1 78  ? 273.812 210.864 210.177 1.00 44.22  ? 90  LYS   B CD     1 
ATOM   1544 C CE     . LYS   E 1 78  ? 273.408 209.611 210.924 1.00 43.93  ? 90  LYS   B CE     1 
ATOM   1545 N NZ     . LYS   E 1 78  ? 272.211 209.848 211.771 1.00 50.86  ? 90  LYS   B NZ     1 
ATOM   1546 N N      . LYS   E 1 79  ? 276.456 213.999 206.137 1.00 42.76  ? 91  LYS   B N      1 
ATOM   1547 C CA     . LYS   E 1 79  ? 277.488 214.981 205.839 1.00 44.35  ? 91  LYS   B CA     1 
ATOM   1548 C C      . LYS   E 1 79  ? 276.974 215.968 204.803 1.00 46.41  ? 91  LYS   B C      1 
ATOM   1549 O O      . LYS   E 1 79  ? 276.300 215.580 203.844 1.00 53.14  ? 91  LYS   B O      1 
ATOM   1550 C CB     . LYS   E 1 79  ? 278.765 214.307 205.319 1.00 43.09  ? 91  LYS   B CB     1 
ATOM   1551 C CG     . LYS   E 1 79  ? 279.414 213.345 206.297 1.00 44.29  ? 91  LYS   B CG     1 
ATOM   1552 C CD     . LYS   E 1 79  ? 280.698 212.768 205.725 1.00 44.29  ? 91  LYS   B CD     1 
ATOM   1553 C CE     . LYS   E 1 79  ? 281.929 213.336 206.406 1.00 39.35  ? 91  LYS   B CE     1 
ATOM   1554 N NZ     . LYS   E 1 79  ? 281.902 213.100 207.871 1.00 41.03  ? 91  LYS   B NZ     1 
ATOM   1555 N N      . THR   E 1 80  ? 277.293 217.243 205.001 1.00 42.22  ? 92  THR   B N      1 
ATOM   1556 C CA     . THR   E 1 80  ? 276.978 218.300 204.050 1.00 44.25  ? 92  THR   B CA     1 
ATOM   1557 C C      . THR   E 1 80  ? 278.248 219.074 203.728 1.00 44.40  ? 92  THR   B C      1 
ATOM   1558 O O      . THR   E 1 80  ? 279.308 218.849 204.317 1.00 49.88  ? 92  THR   B O      1 
ATOM   1559 C CB     . THR   E 1 80  ? 275.898 219.248 204.585 1.00 45.08  ? 92  THR   B CB     1 
ATOM   1560 O OG1    . THR   E 1 80  ? 276.465 220.118 205.572 1.00 42.12  ? 92  THR   B OG1    1 
ATOM   1561 C CG2    . THR   E 1 80  ? 274.756 218.471 205.189 1.00 48.20  ? 92  THR   B CG2    1 
ATOM   1562 N N      . GLY   E 1 81  ? 278.131 219.996 202.782 1.00 41.13  ? 93  GLY   B N      1 
ATOM   1563 C CA     . GLY   E 1 81  ? 279.277 220.788 202.383 1.00 42.62  ? 93  GLY   B CA     1 
ATOM   1564 C C      . GLY   E 1 81  ? 278.970 221.583 201.132 1.00 44.79  ? 93  GLY   B C      1 
ATOM   1565 O O      . GLY   E 1 81  ? 277.808 221.782 200.776 1.00 50.17  ? 93  GLY   B O      1 
ATOM   1566 N N      . GLY   E 1 82  ? 280.033 222.033 200.478 1.00 42.49  ? 94  GLY   B N      1 
ATOM   1567 C CA     . GLY   E 1 82  ? 279.909 222.833 199.287 1.00 42.26  ? 94  GLY   B CA     1 
ATOM   1568 C C      . GLY   E 1 82  ? 281.252 223.320 198.792 1.00 43.86  ? 94  GLY   B C      1 
ATOM   1569 O O      . GLY   E 1 82  ? 282.303 223.003 199.355 1.00 43.98  ? 94  GLY   B O      1 
ATOM   1570 N N      . PRO   E 1 83  ? 281.242 224.097 197.710 1.00 42.76  ? 95  PRO   B N      1 
ATOM   1571 C CA     . PRO   E 1 83  ? 282.499 224.618 197.153 1.00 43.00  ? 95  PRO   B CA     1 
ATOM   1572 C C      . PRO   E 1 83  ? 283.072 225.718 198.034 1.00 44.91  ? 95  PRO   B C      1 
ATOM   1573 O O      . PRO   E 1 83  ? 282.426 226.738 198.275 1.00 47.86  ? 95  PRO   B O      1 
ATOM   1574 C CB     . PRO   E 1 83  ? 282.082 225.156 195.778 1.00 43.59  ? 95  PRO   B CB     1 
ATOM   1575 C CG     . PRO   E 1 83  ? 280.723 224.583 195.517 1.00 40.24  ? 95  PRO   B CG     1 
ATOM   1576 C CD     . PRO   E 1 83  ? 280.091 224.418 196.855 1.00 41.30  ? 95  PRO   B CD     1 
ATOM   1577 N N      . ILE   E 1 84  ? 284.294 225.506 198.512 1.00 44.20  ? 96  ILE   B N      1 
ATOM   1578 C CA     . ILE   E 1 84  ? 285.051 226.521 199.235 1.00 43.20  ? 96  ILE   B CA     1 
ATOM   1579 C C      . ILE   E 1 84  ? 286.199 226.959 198.337 1.00 41.61  ? 96  ILE   B C      1 
ATOM   1580 O O      . ILE   E 1 84  ? 286.983 226.125 197.869 1.00 44.32  ? 96  ILE   B O      1 
ATOM   1581 C CB     . ILE   E 1 84  ? 285.567 225.999 200.584 1.00 44.63  ? 96  ILE   B CB     1 
ATOM   1582 C CG1    . ILE   E 1 84  ? 284.417 225.853 201.579 1.00 42.64  ? 96  ILE   B CG1    1 
ATOM   1583 C CG2    . ILE   E 1 84  ? 286.617 226.937 201.142 1.00 45.75  ? 96  ILE   B CG2    1 
ATOM   1584 C CD1    . ILE   E 1 84  ? 283.700 227.145 201.874 1.00 43.82  ? 96  ILE   B CD1    1 
ATOM   1585 N N      . TYR   E 1 85  ? 286.295 228.261 198.092 1.00 41.20  ? 97  TYR   B N      1 
ATOM   1586 C CA     . TYR   E 1 85  ? 287.271 228.813 197.163 1.00 42.71  ? 97  TYR   B CA     1 
ATOM   1587 C C      . TYR   E 1 85  ? 288.405 229.461 197.947 1.00 42.79  ? 97  TYR   B C      1 
ATOM   1588 O O      . TYR   E 1 85  ? 288.167 230.345 198.776 1.00 44.00  ? 97  TYR   B O      1 
ATOM   1589 C CB     . TYR   E 1 85  ? 286.611 229.824 196.226 1.00 41.15  ? 97  TYR   B CB     1 
ATOM   1590 C CG     . TYR   E 1 85  ? 285.390 229.285 195.514 1.00 42.37  ? 97  TYR   B CG     1 
ATOM   1591 C CD1    . TYR   E 1 85  ? 284.141 229.324 196.115 1.00 42.24  ? 97  TYR   B CD1    1 
ATOM   1592 C CD2    . TYR   E 1 85  ? 285.489 228.725 194.250 1.00 43.68  ? 97  TYR   B CD2    1 
ATOM   1593 C CE1    . TYR   E 1 85  ? 283.024 228.830 195.473 1.00 41.13  ? 97  TYR   B CE1    1 
ATOM   1594 C CE2    . TYR   E 1 85  ? 284.378 228.226 193.602 1.00 42.77  ? 97  TYR   B CE2    1 
ATOM   1595 C CZ     . TYR   E 1 85  ? 283.149 228.282 194.219 1.00 39.37  ? 97  TYR   B CZ     1 
ATOM   1596 O OH     . TYR   E 1 85  ? 282.038 227.790 193.579 1.00 42.04  ? 97  TYR   B OH     1 
ATOM   1597 N N      . ARG   E 1 86  ? 289.632 229.023 197.681 1.00 43.71  ? 98  ARG   B N      1 
ATOM   1598 C CA     . ARG   E 1 86  ? 290.821 229.543 198.339 1.00 43.40  ? 98  ARG   B CA     1 
ATOM   1599 C C      . ARG   E 1 86  ? 291.777 230.107 197.299 1.00 44.14  ? 98  ARG   B C      1 
ATOM   1600 O O      . ARG   E 1 86  ? 291.914 229.556 196.203 1.00 44.45  ? 98  ARG   B O      1 
ATOM   1601 C CB     . ARG   E 1 86  ? 291.530 228.460 199.157 1.00 40.37  ? 98  ARG   B CB     1 
ATOM   1602 C CG     . ARG   E 1 86  ? 290.705 227.884 200.290 1.00 41.18  ? 98  ARG   B CG     1 
ATOM   1603 C CD     . ARG   E 1 86  ? 291.047 226.424 200.513 1.00 46.12  ? 98  ARG   B CD     1 
ATOM   1604 N NE     . ARG   E 1 86  ? 290.218 225.808 201.541 1.00 47.05  ? 98  ARG   B NE     1 
ATOM   1605 C CZ     . ARG   E 1 86  ? 290.282 226.105 202.831 1.00 40.91  ? 98  ARG   B CZ     1 
ATOM   1606 N NH1    . ARG   E 1 86  ? 291.111 227.028 203.286 1.00 40.96  ? 98  ARG   B NH1    1 
ATOM   1607 N NH2    . ARG   E 1 86  ? 289.492 225.460 203.684 1.00 42.84  ? 98  ARG   B NH2    1 
ATOM   1608 N N      . ARG   E 1 87  ? 292.435 231.206 197.648 1.00 42.70  ? 99  ARG   B N      1 
ATOM   1609 C CA     . ARG   E 1 87  ? 293.391 231.864 196.767 1.00 44.95  ? 99  ARG   B CA     1 
ATOM   1610 C C      . ARG   E 1 87  ? 294.803 231.511 197.220 1.00 48.48  ? 99  ARG   B C      1 
ATOM   1611 O O      . ARG   E 1 87  ? 295.251 231.956 198.281 1.00 50.38  ? 99  ARG   B O      1 
ATOM   1612 C CB     . ARG   E 1 87  ? 293.176 233.374 196.766 1.00 45.47  ? 99  ARG   B CB     1 
ATOM   1613 C CG     . ARG   E 1 87  ? 294.079 234.124 195.811 1.00 43.44  ? 99  ARG   B CG     1 
ATOM   1614 C CD     . ARG   E 1 87  ? 293.476 235.459 195.435 1.00 43.76  ? 99  ARG   B CD     1 
ATOM   1615 N NE     . ARG   E 1 87  ? 293.833 236.492 196.398 1.00 43.20  ? 99  ARG   B NE     1 
ATOM   1616 C CZ     . ARG   E 1 87  ? 293.691 237.792 196.187 1.00 54.68  ? 99  ARG   B CZ     1 
ATOM   1617 N NH1    . ARG   E 1 87  ? 293.205 238.259 195.049 1.00 58.08  ? 99  ARG   B NH1    1 
ATOM   1618 N NH2    . ARG   E 1 87  ? 294.041 238.646 197.145 1.00 61.82  ? 99  ARG   B NH2    1 
ATOM   1619 N N      . VAL   E 1 88  ? 295.500 230.717 196.414 1.00 50.70  ? 100 VAL   B N      1 
ATOM   1620 C CA     . VAL   E 1 88  ? 296.880 230.332 196.680 1.00 49.50  ? 100 VAL   B CA     1 
ATOM   1621 C C      . VAL   E 1 88  ? 297.738 230.806 195.517 1.00 55.55  ? 100 VAL   B C      1 
ATOM   1622 O O      . VAL   E 1 88  ? 297.423 230.527 194.355 1.00 60.22  ? 100 VAL   B O      1 
ATOM   1623 C CB     . VAL   E 1 88  ? 297.018 228.813 196.883 1.00 51.08  ? 100 VAL   B CB     1 
ATOM   1624 C CG1    . VAL   E 1 88  ? 298.480 228.434 197.035 1.00 55.80  ? 100 VAL   B CG1    1 
ATOM   1625 C CG2    . VAL   E 1 88  ? 296.217 228.368 198.093 1.00 48.82  ? 100 VAL   B CG2    1 
ATOM   1626 N N      . ASP   E 1 89  ? 298.811 231.528 195.833 1.00 56.39  ? 101 ASP   B N      1 
ATOM   1627 C CA     . ASP   E 1 89  ? 299.764 232.024 194.837 1.00 58.22  ? 101 ASP   B CA     1 
ATOM   1628 C C      . ASP   E 1 89  ? 299.100 232.948 193.816 1.00 60.36  ? 101 ASP   B C      1 
ATOM   1629 O O      . ASP   E 1 89  ? 299.601 233.139 192.707 1.00 64.58  ? 101 ASP   B O      1 
ATOM   1630 C CB     . ASP   E 1 89  ? 300.514 230.858 194.172 1.00 63.25  ? 101 ASP   B CB     1 
ATOM   1631 C CG     . ASP   E 1 89  ? 299.837 230.311 192.908 1.00 72.62  ? 101 ASP   B CG     1 
ATOM   1632 O OD1    . ASP   E 1 89  ? 298.838 230.864 192.406 1.00 70.62  ? 101 ASP   B OD1    1 
ATOM   1633 O OD2    . ASP   E 1 89  ? 300.329 229.283 192.405 1.00 82.92  ? 101 ASP   B OD2    1 
ATOM   1634 N N      . GLY   E 1 90  ? 297.987 233.559 194.209 1.00 56.37  ? 102 GLY   B N      1 
ATOM   1635 C CA     . GLY   E 1 90  ? 297.304 234.504 193.347 1.00 57.92  ? 102 GLY   B CA     1 
ATOM   1636 C C      . GLY   E 1 90  ? 296.202 233.909 192.495 1.00 57.64  ? 102 GLY   B C      1 
ATOM   1637 O O      . GLY   E 1 90  ? 295.342 234.636 191.991 1.00 57.99  ? 102 GLY   B O      1 
ATOM   1638 N N      . LYS   E 1 91  ? 296.219 232.595 192.309 1.00 56.74  ? 103 LYS   B N      1 
ATOM   1639 C CA     . LYS   E 1 91  ? 295.180 231.929 191.541 1.00 54.44  ? 103 LYS   B CA     1 
ATOM   1640 C C      . LYS   E 1 91  ? 294.129 231.321 192.466 1.00 52.67  ? 103 LYS   B C      1 
ATOM   1641 O O      . LYS   E 1 91  ? 294.393 231.000 193.626 1.00 53.35  ? 103 LYS   B O      1 
ATOM   1642 C CB     . LYS   E 1 91  ? 295.782 230.852 190.640 1.00 55.37  ? 103 LYS   B CB     1 
ATOM   1643 C CG     . LYS   E 1 91  ? 295.123 230.757 189.278 1.00 59.85  ? 103 LYS   B CG     1 
ATOM   1644 C CD     . LYS   E 1 91  ? 296.042 230.093 188.270 1.00 67.58  ? 103 LYS   B CD     1 
ATOM   1645 C CE     . LYS   E 1 91  ? 297.309 230.902 188.072 1.00 73.93  ? 103 LYS   B CE     1 
ATOM   1646 N NZ     . LYS   E 1 91  ? 297.034 232.363 188.115 1.00 81.01  ? 103 LYS   B NZ     1 
ATOM   1647 N N      . TRP   E 1 92  ? 292.924 231.166 191.929 1.00 50.50  ? 104 TRP   B N      1 
ATOM   1648 C CA     . TRP   E 1 92  ? 291.789 230.680 192.697 1.00 48.07  ? 104 TRP   B CA     1 
ATOM   1649 C C      . TRP   E 1 92  ? 291.544 229.204 192.411 1.00 48.62  ? 104 TRP   B C      1 
ATOM   1650 O O      . TRP   E 1 92  ? 291.628 228.750 191.267 1.00 52.08  ? 104 TRP   B O      1 
ATOM   1651 C CB     . TRP   E 1 92  ? 290.532 231.488 192.369 1.00 46.34  ? 104 TRP   B CB     1 
ATOM   1652 C CG     . TRP   E 1 92  ? 290.489 232.824 193.040 1.00 45.79  ? 104 TRP   B CG     1 
ATOM   1653 C CD1    . TRP   E 1 92  ? 290.880 234.016 192.509 1.00 46.48  ? 104 TRP   B CD1    1 
ATOM   1654 C CD2    . TRP   E 1 92  ? 290.024 233.108 194.364 1.00 44.81  ? 104 TRP   B CD2    1 
ATOM   1655 N NE1    . TRP   E 1 92  ? 290.696 235.024 193.422 1.00 46.25  ? 104 TRP   B NE1    1 
ATOM   1656 C CE2    . TRP   E 1 92  ? 290.170 234.493 194.569 1.00 44.80  ? 104 TRP   B CE2    1 
ATOM   1657 C CE3    . TRP   E 1 92  ? 289.504 232.326 195.398 1.00 44.60  ? 104 TRP   B CE3    1 
ATOM   1658 C CZ2    . TRP   E 1 92  ? 289.814 235.112 195.763 1.00 42.91  ? 104 TRP   B CZ2    1 
ATOM   1659 C CZ3    . TRP   E 1 92  ? 289.151 232.943 196.582 1.00 45.13  ? 104 TRP   B CZ3    1 
ATOM   1660 C CH2    . TRP   E 1 92  ? 289.307 234.321 196.755 1.00 42.16  ? 104 TRP   B CH2    1 
ATOM   1661 N N      . ARG   E 1 93  ? 291.229 228.459 193.467 1.00 49.04  ? 105 ARG   B N      1 
ATOM   1662 C CA     . ARG   E 1 93  ? 290.948 227.036 193.353 1.00 47.30  ? 105 ARG   B CA     1 
ATOM   1663 C C      . ARG   E 1 93  ? 289.754 226.688 194.227 1.00 45.89  ? 105 ARG   B C      1 
ATOM   1664 O O      . ARG   E 1 93  ? 289.509 227.322 195.255 1.00 45.98  ? 105 ARG   B O      1 
ATOM   1665 C CB     . ARG   E 1 93  ? 292.161 226.186 193.752 1.00 47.34  ? 105 ARG   B CB     1 
ATOM   1666 C CG     . ARG   E 1 93  ? 292.871 226.666 195.002 1.00 51.79  ? 105 ARG   B CG     1 
ATOM   1667 C CD     . ARG   E 1 93  ? 294.147 225.880 195.233 1.00 56.41  ? 105 ARG   B CD     1 
ATOM   1668 N NE     . ARG   E 1 93  ? 294.846 225.613 193.983 1.00 60.67  ? 105 ARG   B NE     1 
ATOM   1669 C CZ     . ARG   E 1 93  ? 296.003 226.161 193.641 1.00 64.81  ? 105 ARG   B CZ     1 
ATOM   1670 N NH1    . ARG   E 1 93  ? 296.628 227.010 194.440 1.00 61.21  ? 105 ARG   B NH1    1 
ATOM   1671 N NH2    . ARG   E 1 93  ? 296.548 225.849 192.469 1.00 67.76  ? 105 ARG   B NH2    1 
ATOM   1672 N N      . ARG   E 1 94  ? 289.012 225.669 193.804 1.00 46.17  ? 106 ARG   B N      1 
ATOM   1673 C CA     . ARG   E 1 94  ? 287.801 225.234 194.484 1.00 44.10  ? 106 ARG   B CA     1 
ATOM   1674 C C      . ARG   E 1 94  ? 288.000 223.815 194.992 1.00 44.19  ? 106 ARG   B C      1 
ATOM   1675 O O      . ARG   E 1 94  ? 288.444 222.940 194.243 1.00 48.46  ? 106 ARG   B O      1 
ATOM   1676 C CB     . ARG   E 1 94  ? 286.592 225.308 193.545 1.00 44.70  ? 106 ARG   B CB     1 
ATOM   1677 C CG     . ARG   E 1 94  ? 286.031 223.963 193.122 1.00 39.66  ? 106 ARG   B CG     1 
ATOM   1678 C CD     . ARG   E 1 94  ? 285.284 224.068 191.804 1.00 43.69  ? 106 ARG   B CD     1 
ATOM   1679 N NE     . ARG   E 1 94  ? 284.161 224.992 191.878 1.00 45.10  ? 106 ARG   B NE     1 
ATOM   1680 C CZ     . ARG   E 1 94  ? 282.930 224.646 192.226 1.00 48.71  ? 106 ARG   B CZ     1 
ATOM   1681 N NH1    . ARG   E 1 94  ? 282.629 223.399 192.548 1.00 54.52  ? 106 ARG   B NH1    1 
ATOM   1682 N NH2    . ARG   E 1 94  ? 281.978 225.572 192.250 1.00 50.11  ? 106 ARG   B NH2    1 
ATOM   1683 N N      . GLU   E 1 95  ? 287.685 223.594 196.264 1.00 43.92  ? 107 GLU   B N      1 
ATOM   1684 C CA     . GLU   E 1 95  ? 287.769 222.273 196.869 1.00 46.33  ? 107 GLU   B CA     1 
ATOM   1685 C C      . GLU   E 1 95  ? 286.490 222.004 197.645 1.00 43.37  ? 107 GLU   B C      1 
ATOM   1686 O O      . GLU   E 1 95  ? 286.043 222.849 198.425 1.00 42.98  ? 107 GLU   B O      1 
ATOM   1687 C CB     . GLU   E 1 95  ? 289.006 222.156 197.769 1.00 47.77  ? 107 GLU   B CB     1 
ATOM   1688 C CG     . GLU   E 1 95  ? 289.057 223.127 198.933 1.00 45.73  ? 107 GLU   B CG     1 
ATOM   1689 C CD     . GLU   E 1 95  ? 288.456 222.557 200.197 1.00 56.06  ? 107 GLU   B CD     1 
ATOM   1690 O OE1    . GLU   E 1 95  ? 288.161 221.344 200.222 1.00 56.64  ? 107 GLU   B OE1    1 
ATOM   1691 O OE2    . GLU   E 1 95  ? 288.288 223.319 201.171 1.00 61.34  ? 107 GLU   B OE2    1 
ATOM   1692 N N      . LEU   E 1 96  ? 285.898 220.835 197.417 1.00 42.33  ? 108 LEU   B N      1 
ATOM   1693 C CA     . LEU   E 1 96  ? 284.619 220.498 198.024 1.00 44.12  ? 108 LEU   B CA     1 
ATOM   1694 C C      . LEU   E 1 96  ? 284.822 220.073 199.471 1.00 46.99  ? 108 LEU   B C      1 
ATOM   1695 O O      . LEU   E 1 96  ? 285.558 219.122 199.753 1.00 51.02  ? 108 LEU   B O      1 
ATOM   1696 C CB     . LEU   E 1 96  ? 283.930 219.386 197.234 1.00 37.80  ? 108 LEU   B CB     1 
ATOM   1697 C CG     . LEU   E 1 96  ? 282.406 219.324 197.358 1.00 37.92  ? 108 LEU   B CG     1 
ATOM   1698 C CD1    . LEU   E 1 96  ? 281.770 218.962 196.031 1.00 34.82  ? 108 LEU   B CD1    1 
ATOM   1699 C CD2    . LEU   E 1 96  ? 281.994 218.340 198.438 1.00 44.83  ? 108 LEU   B CD2    1 
ATOM   1700 N N      . ILE   E 1 97  ? 284.163 220.772 200.384 1.00 46.24  ? 109 ILE   B N      1 
ATOM   1701 C CA     . ILE   E 1 97  ? 284.307 220.536 201.814 1.00 44.24  ? 109 ILE   B CA     1 
ATOM   1702 C C      . ILE   E 1 97  ? 283.129 219.710 202.301 1.00 45.04  ? 109 ILE   B C      1 
ATOM   1703 O O      . ILE   E 1 97  ? 281.972 220.000 201.974 1.00 47.20  ? 109 ILE   B O      1 
ATOM   1704 C CB     . ILE   E 1 97  ? 284.408 221.861 202.590 1.00 44.59  ? 109 ILE   B CB     1 
ATOM   1705 C CG1    . ILE   E 1 97  ? 285.814 222.442 202.465 1.00 45.57  ? 109 ILE   B CG1    1 
ATOM   1706 C CG2    . ILE   E 1 97  ? 284.043 221.650 204.046 1.00 45.97  ? 109 ILE   B CG2    1 
ATOM   1707 C CD1    . ILE   E 1 97  ? 286.831 221.753 203.337 1.00 46.58  ? 109 ILE   B CD1    1 
ATOM   1708 N N      . LEU   E 1 98  ? 283.422 218.681 203.088 1.00 44.60  ? 110 LEU   B N      1 
ATOM   1709 C CA     . LEU   E 1 98  ? 282.408 217.812 203.663 1.00 45.45  ? 110 LEU   B CA     1 
ATOM   1710 C C      . LEU   E 1 98  ? 282.416 217.990 205.172 1.00 46.70  ? 110 LEU   B C      1 
ATOM   1711 O O      . LEU   E 1 98  ? 283.472 217.906 205.806 1.00 45.95  ? 110 LEU   B O      1 
ATOM   1712 C CB     . LEU   E 1 98  ? 282.660 216.350 203.294 1.00 45.49  ? 110 LEU   B CB     1 
ATOM   1713 C CG     . LEU   E 1 98  ? 281.999 215.885 201.998 1.00 47.83  ? 110 LEU   B CG     1 
ATOM   1714 C CD1    . LEU   E 1 98  ? 282.441 214.479 201.648 1.00 45.22  ? 110 LEU   B CD1    1 
ATOM   1715 C CD2    . LEU   E 1 98  ? 280.490 215.964 202.112 1.00 50.50  ? 110 LEU   B CD2    1 
ATOM   1716 N N      . TYR   E 1 99  ? 281.242 218.240 205.740 1.00 47.21  ? 111 TYR   B N      1 
ATOM   1717 C CA     . TYR   E 1 99  ? 281.113 218.513 207.161 1.00 42.91  ? 111 TYR   B CA     1 
ATOM   1718 C C      . TYR   E 1 99  ? 279.957 217.703 207.722 1.00 43.53  ? 111 TYR   B C      1 
ATOM   1719 O O      . TYR   E 1 99  ? 278.945 217.505 207.046 1.00 48.19  ? 111 TYR   B O      1 
ATOM   1720 C CB     . TYR   E 1 99  ? 280.884 220.006 207.415 1.00 44.22  ? 111 TYR   B CB     1 
ATOM   1721 C CG     . TYR   E 1 99  ? 282.053 220.702 208.064 1.00 43.27  ? 111 TYR   B CG     1 
ATOM   1722 C CD1    . TYR   E 1 99  ? 282.242 220.653 209.436 1.00 42.91  ? 111 TYR   B CD1    1 
ATOM   1723 C CD2    . TYR   E 1 99  ? 282.975 221.400 207.300 1.00 45.53  ? 111 TYR   B CD2    1 
ATOM   1724 C CE1    . TYR   E 1 99  ? 283.311 221.288 210.029 1.00 44.41  ? 111 TYR   B CE1    1 
ATOM   1725 C CE2    . TYR   E 1 99  ? 284.048 222.036 207.884 1.00 45.59  ? 111 TYR   B CE2    1 
ATOM   1726 C CZ     . TYR   E 1 99  ? 284.211 221.977 209.247 1.00 47.58  ? 111 TYR   B CZ     1 
ATOM   1727 O OH     . TYR   E 1 99  ? 285.282 222.611 209.830 1.00 55.89  ? 111 TYR   B OH     1 
ATOM   1728 N N      . ASP   E 1 100 ? 280.119 217.228 208.951 1.00 42.98  ? 112 ASP   B N      1 
ATOM   1729 C CA     . ASP   E 1 100 ? 279.040 216.515 209.617 1.00 42.83  ? 112 ASP   B CA     1 
ATOM   1730 C C      . ASP   E 1 100 ? 277.916 217.478 209.971 1.00 41.35  ? 112 ASP   B C      1 
ATOM   1731 O O      . ASP   E 1 100 ? 278.152 218.563 210.508 1.00 42.02  ? 112 ASP   B O      1 
ATOM   1732 C CB     . ASP   E 1 100 ? 279.557 215.819 210.873 1.00 43.35  ? 112 ASP   B CB     1 
ATOM   1733 C CG     . ASP   E 1 100 ? 280.848 215.070 210.630 1.00 50.84  ? 112 ASP   B CG     1 
ATOM   1734 O OD1    . ASP   E 1 100 ? 281.753 215.639 209.986 1.00 50.50  ? 112 ASP   B OD1    1 
ATOM   1735 O OD2    . ASP   E 1 100 ? 280.958 213.912 211.082 1.00 57.48  ? 112 ASP   B OD2    1 
ATOM   1736 N N      . LYS   E 1 101 ? 276.684 217.077 209.660 1.00 41.49  ? 113 LYS   B N      1 
ATOM   1737 C CA     . LYS   E 1 101 ? 275.543 217.937 209.945 1.00 42.46  ? 113 LYS   B CA     1 
ATOM   1738 C C      . LYS   E 1 101 ? 275.404 218.178 211.441 1.00 41.11  ? 113 LYS   B C      1 
ATOM   1739 O O      . LYS   E 1 101 ? 275.000 219.265 211.868 1.00 40.89  ? 113 LYS   B O      1 
ATOM   1740 C CB     . LYS   E 1 101 ? 274.270 217.324 209.363 1.00 39.38  ? 113 LYS   B CB     1 
ATOM   1741 C CG     . LYS   E 1 101 ? 274.371 217.072 207.872 1.00 39.71  ? 113 LYS   B CG     1 
ATOM   1742 C CD     . LYS   E 1 101 ? 273.277 216.164 207.347 1.00 41.23  ? 113 LYS   B CD     1 
ATOM   1743 C CE     . LYS   E 1 101 ? 272.343 216.922 206.422 1.00 39.98  ? 113 LYS   B CE     1 
ATOM   1744 N NZ     . LYS   E 1 101 ? 271.901 216.085 205.275 1.00 36.59  ? 113 LYS   B NZ     1 
ATOM   1745 N N      . GLU   E 1 102 ? 275.739 217.176 212.253 1.00 44.71  ? 114 GLU   B N      1 
ATOM   1746 C CA     . GLU   E 1 102 ? 275.720 217.361 213.698 1.00 47.23  ? 114 GLU   B CA     1 
ATOM   1747 C C      . GLU   E 1 102 ? 276.763 218.383 214.129 1.00 41.38  ? 114 GLU   B C      1 
ATOM   1748 O O      . GLU   E 1 102 ? 276.529 219.172 215.051 1.00 41.63  ? 114 GLU   B O      1 
ATOM   1749 C CB     . GLU   E 1 102 ? 275.947 216.021 214.393 1.00 46.73  ? 114 GLU   B CB     1 
ATOM   1750 C CG     . GLU   E 1 102 ? 275.402 215.950 215.802 1.00 53.16  ? 114 GLU   B CG     1 
ATOM   1751 C CD     . GLU   E 1 102 ? 275.499 214.557 216.382 1.00 69.68  ? 114 GLU   B CD     1 
ATOM   1752 O OE1    . GLU   E 1 102 ? 274.812 214.280 217.387 1.00 81.70  ? 114 GLU   B OE1    1 
ATOM   1753 O OE2    . GLU   E 1 102 ? 276.257 213.736 215.826 1.00 70.89  ? 114 GLU   B OE2    1 
ATOM   1754 N N      . GLU   E 1 103 ? 277.922 218.381 213.472 1.00 40.42  ? 115 GLU   B N      1 
ATOM   1755 C CA     . GLU   E 1 103 ? 278.963 219.347 213.802 1.00 42.34  ? 115 GLU   B CA     1 
ATOM   1756 C C      . GLU   E 1 103 ? 278.525 220.765 213.453 1.00 41.53  ? 115 GLU   B C      1 
ATOM   1757 O O      . GLU   E 1 103 ? 278.777 221.707 214.213 1.00 41.18  ? 115 GLU   B O      1 
ATOM   1758 C CB     . GLU   E 1 103 ? 280.252 218.984 213.067 1.00 43.56  ? 115 GLU   B CB     1 
ATOM   1759 C CG     . GLU   E 1 103 ? 281.424 219.876 213.393 1.00 46.98  ? 115 GLU   B CG     1 
ATOM   1760 C CD     . GLU   E 1 103 ? 282.134 219.433 214.651 1.00 53.10  ? 115 GLU   B CD     1 
ATOM   1761 O OE1    . GLU   E 1 103 ? 281.829 218.325 215.140 1.00 46.41  ? 115 GLU   B OE1    1 
ATOM   1762 O OE2    . GLU   E 1 103 ? 282.994 220.188 215.150 1.00 59.67  ? 115 GLU   B OE2    1 
ATOM   1763 N N      . ILE   E 1 104 ? 277.877 220.936 212.299 1.00 39.84  ? 116 ILE   B N      1 
ATOM   1764 C CA     . ILE   E 1 104 ? 277.397 222.256 211.899 1.00 40.49  ? 116 ILE   B CA     1 
ATOM   1765 C C      . ILE   E 1 104 ? 276.264 222.714 212.808 1.00 40.45  ? 116 ILE   B C      1 
ATOM   1766 O O      . ILE   E 1 104 ? 276.184 223.890 213.181 1.00 38.81  ? 116 ILE   B O      1 
ATOM   1767 C CB     . ILE   E 1 104 ? 276.966 222.242 210.421 1.00 40.85  ? 116 ILE   B CB     1 
ATOM   1768 C CG1    . ILE   E 1 104 ? 278.159 221.917 209.525 1.00 42.61  ? 116 ILE   B CG1    1 
ATOM   1769 C CG2    . ILE   E 1 104 ? 276.368 223.579 210.030 1.00 42.91  ? 116 ILE   B CG2    1 
ATOM   1770 C CD1    . ILE   E 1 104 ? 279.205 223.003 209.499 1.00 46.58  ? 116 ILE   B CD1    1 
ATOM   1771 N N      . ARG   E 1 105 ? 275.362 221.799 213.166 1.00 42.00  ? 117 ARG   B N      1 
ATOM   1772 C CA     . ARG   E 1 105 ? 274.258 222.160 214.050 1.00 38.93  ? 117 ARG   B CA     1 
ATOM   1773 C C      . ARG   E 1 105 ? 274.772 222.606 215.413 1.00 38.13  ? 117 ARG   B C      1 
ATOM   1774 O O      . ARG   E 1 105 ? 274.282 223.588 215.981 1.00 40.03  ? 117 ARG   B O      1 
ATOM   1775 C CB     . ARG   E 1 105 ? 273.293 220.984 214.195 1.00 38.17  ? 117 ARG   B CB     1 
ATOM   1776 C CG     . ARG   E 1 105 ? 272.441 220.719 212.964 1.00 37.40  ? 117 ARG   B CG     1 
ATOM   1777 C CD     . ARG   E 1 105 ? 271.222 219.877 213.300 1.00 39.41  ? 117 ARG   B CD     1 
ATOM   1778 N NE     . ARG   E 1 105 ? 271.575 218.561 213.817 1.00 45.01  ? 117 ARG   B NE     1 
ATOM   1779 C CZ     . ARG   E 1 105 ? 271.767 217.486 213.065 1.00 44.57  ? 117 ARG   B CZ     1 
ATOM   1780 N NH1    . ARG   E 1 105 ? 271.630 217.528 211.751 1.00 48.22  ? 117 ARG   B NH1    1 
ATOM   1781 N NH2    . ARG   E 1 105 ? 272.096 216.337 213.648 1.00 42.24  ? 117 ARG   B NH2    1 
ATOM   1782 N N      . ARG   E 1 106 ? 275.763 221.895 215.953 1.00 37.77  ? 118 ARG   B N      1 
ATOM   1783 C CA     . ARG   E 1 106 ? 276.337 222.285 217.235 1.00 37.07  ? 118 ARG   B CA     1 
ATOM   1784 C C      . ARG   E 1 106 ? 277.012 223.647 217.145 1.00 40.06  ? 118 ARG   B C      1 
ATOM   1785 O O      . ARG   E 1 106 ? 276.893 224.470 218.060 1.00 41.12  ? 118 ARG   B O      1 
ATOM   1786 C CB     . ARG   E 1 106 ? 277.322 221.215 217.706 1.00 37.62  ? 118 ARG   B CB     1 
ATOM   1787 C CG     . ARG   E 1 106 ? 278.171 221.614 218.895 1.00 37.73  ? 118 ARG   B CG     1 
ATOM   1788 C CD     . ARG   E 1 106 ? 279.239 220.570 219.169 1.00 38.96  ? 118 ARG   B CD     1 
ATOM   1789 N NE     . ARG   E 1 106 ? 280.306 220.596 218.177 1.00 41.07  ? 118 ARG   B NE     1 
ATOM   1790 C CZ     . ARG   E 1 106 ? 281.289 221.483 218.158 1.00 43.17  ? 118 ARG   B CZ     1 
ATOM   1791 N NH1    . ARG   E 1 106 ? 281.368 222.446 219.061 1.00 44.46  ? 118 ARG   B NH1    1 
ATOM   1792 N NH2    . ARG   E 1 106 ? 282.215 221.405 217.208 1.00 42.42  ? 118 ARG   B NH2    1 
ATOM   1793 N N      . ILE   E 1 107 ? 277.725 223.905 216.047 1.00 42.47  ? 119 ILE   B N      1 
ATOM   1794 C CA     . ILE   E 1 107 ? 278.399 225.190 215.882 1.00 39.29  ? 119 ILE   B CA     1 
ATOM   1795 C C      . ILE   E 1 107 ? 277.383 226.320 215.793 1.00 39.30  ? 119 ILE   B C      1 
ATOM   1796 O O      . ILE   E 1 107 ? 277.564 227.386 216.393 1.00 38.78  ? 119 ILE   B O      1 
ATOM   1797 C CB     . ILE   E 1 107 ? 279.320 225.152 214.650 1.00 39.18  ? 119 ILE   B CB     1 
ATOM   1798 C CG1    . ILE   E 1 107 ? 280.456 224.154 214.872 1.00 40.34  ? 119 ILE   B CG1    1 
ATOM   1799 C CG2    . ILE   E 1 107 ? 279.874 226.532 214.356 1.00 39.85  ? 119 ILE   B CG2    1 
ATOM   1800 C CD1    . ILE   E 1 107 ? 281.364 223.996 213.681 1.00 43.78  ? 119 ILE   B CD1    1 
ATOM   1801 N N      . TRP   E 1 108 ? 276.304 226.113 215.034 1.00 39.64  ? 120 TRP   B N      1 
ATOM   1802 C CA     . TRP   E 1 108 ? 275.267 227.135 214.937 1.00 39.18  ? 120 TRP   B CA     1 
ATOM   1803 C C      . TRP   E 1 108 ? 274.609 227.387 216.287 1.00 41.25  ? 120 TRP   B C      1 
ATOM   1804 O O      . TRP   E 1 108 ? 274.413 228.541 216.685 1.00 42.34  ? 120 TRP   B O      1 
ATOM   1805 C CB     . TRP   E 1 108 ? 274.221 226.721 213.904 1.00 38.98  ? 120 TRP   B CB     1 
ATOM   1806 C CG     . TRP   E 1 108 ? 272.996 227.583 213.900 1.00 40.18  ? 120 TRP   B CG     1 
ATOM   1807 C CD1    . TRP   E 1 108 ? 271.812 227.322 214.520 1.00 40.50  ? 120 TRP   B CD1    1 
ATOM   1808 C CD2    . TRP   E 1 108 ? 272.831 228.841 213.235 1.00 42.05  ? 120 TRP   B CD2    1 
ATOM   1809 N NE1    . TRP   E 1 108 ? 270.920 228.338 214.287 1.00 38.87  ? 120 TRP   B NE1    1 
ATOM   1810 C CE2    . TRP   E 1 108 ? 271.521 229.283 213.498 1.00 39.49  ? 120 TRP   B CE2    1 
ATOM   1811 C CE3    . TRP   E 1 108 ? 273.663 229.636 212.443 1.00 41.63  ? 120 TRP   B CE3    1 
ATOM   1812 C CZ2    . TRP   E 1 108 ? 271.025 230.484 213.001 1.00 38.17  ? 120 TRP   B CZ2    1 
ATOM   1813 C CZ3    . TRP   E 1 108 ? 273.168 230.827 211.952 1.00 39.80  ? 120 TRP   B CZ3    1 
ATOM   1814 C CH2    . TRP   E 1 108 ? 271.863 231.239 212.231 1.00 38.53  ? 120 TRP   B CH2    1 
ATOM   1815 N N      . ARG   E 1 109 ? 274.259 226.320 217.006 1.00 40.83  ? 121 ARG   B N      1 
ATOM   1816 C CA     . ARG   E 1 109 ? 273.607 226.487 218.300 1.00 40.81  ? 121 ARG   B CA     1 
ATOM   1817 C C      . ARG   E 1 109 ? 274.526 227.176 219.299 1.00 41.79  ? 121 ARG   B C      1 
ATOM   1818 O O      . ARG   E 1 109 ? 274.079 228.030 220.073 1.00 44.75  ? 121 ARG   B O      1 
ATOM   1819 C CB     . ARG   E 1 109 ? 273.147 225.132 218.832 1.00 39.89  ? 121 ARG   B CB     1 
ATOM   1820 C CG     . ARG   E 1 109 ? 271.816 224.679 218.270 1.00 42.42  ? 121 ARG   B CG     1 
ATOM   1821 C CD     . ARG   E 1 109 ? 271.451 223.302 218.776 1.00 41.67  ? 121 ARG   B CD     1 
ATOM   1822 N NE     . ARG   E 1 109 ? 270.386 222.701 217.985 1.00 39.90  ? 121 ARG   B NE     1 
ATOM   1823 C CZ     . ARG   E 1 109 ? 270.342 221.421 217.646 1.00 41.46  ? 121 ARG   B CZ     1 
ATOM   1824 N NH1    . ARG   E 1 109 ? 271.299 220.580 217.999 1.00 38.96  ? 121 ARG   B NH1    1 
ATOM   1825 N NH2    . ARG   E 1 109 ? 269.313 220.974 216.934 1.00 44.36  ? 121 ARG   B NH2    1 
ATOM   1826 N N      . GLN   E 1 110 ? 275.811 226.820 219.301 1.00 40.37  ? 122 GLN   B N      1 
ATOM   1827 C CA     . GLN   E 1 110 ? 276.747 227.460 220.219 1.00 40.95  ? 122 GLN   B CA     1 
ATOM   1828 C C      . GLN   E 1 110 ? 276.870 228.950 219.927 1.00 42.49  ? 122 GLN   B C      1 
ATOM   1829 O O      . GLN   E 1 110 ? 277.001 229.762 220.850 1.00 45.64  ? 122 GLN   B O      1 
ATOM   1830 C CB     . GLN   E 1 110 ? 278.111 226.777 220.139 1.00 41.19  ? 122 GLN   B CB     1 
ATOM   1831 C CG     . GLN   E 1 110 ? 279.289 227.725 220.244 1.00 41.22  ? 122 GLN   B CG     1 
ATOM   1832 C CD     . GLN   E 1 110 ? 280.600 226.998 220.447 1.00 43.91  ? 122 GLN   B CD     1 
ATOM   1833 O OE1    . GLN   E 1 110 ? 280.773 225.869 219.992 1.00 47.62  ? 122 GLN   B OE1    1 
ATOM   1834 N NE2    . GLN   E 1 110 ? 281.533 227.643 221.133 1.00 47.96  ? 122 GLN   B NE2    1 
ATOM   1835 N N      . ALA   E 1 111 ? 276.829 229.328 218.649 1.00 41.90  ? 123 ALA   B N      1 
ATOM   1836 C CA     . ALA   E 1 111 ? 276.911 230.736 218.282 1.00 41.62  ? 123 ALA   B CA     1 
ATOM   1837 C C      . ALA   E 1 111 ? 275.696 231.533 218.740 1.00 40.87  ? 123 ALA   B C      1 
ATOM   1838 O O      . ALA   E 1 111 ? 275.823 232.734 218.998 1.00 41.84  ? 123 ALA   B O      1 
ATOM   1839 C CB     . ALA   E 1 111 ? 277.081 230.874 216.769 1.00 41.73  ? 123 ALA   B CB     1 
ATOM   1840 N N      . ASN   E 1 112 ? 274.529 230.899 218.853 1.00 41.57  ? 124 ASN   B N      1 
ATOM   1841 C CA     . ASN   E 1 112 ? 273.310 231.565 219.296 1.00 42.88  ? 124 ASN   B CA     1 
ATOM   1842 C C      . ASN   E 1 112 ? 272.967 231.231 220.744 1.00 44.29  ? 124 ASN   B C      1 
ATOM   1843 O O      . ASN   E 1 112 ? 271.794 231.216 221.122 1.00 45.32  ? 124 ASN   B O      1 
ATOM   1844 C CB     . ASN   E 1 112 ? 272.137 231.215 218.383 1.00 41.56  ? 124 ASN   B CB     1 
ATOM   1845 C CG     . ASN   E 1 112 ? 272.438 231.472 216.927 1.00 45.15  ? 124 ASN   B CG     1 
ATOM   1846 O OD1    . ASN   E 1 112 ? 273.353 232.222 216.592 1.00 51.55  ? 124 ASN   B OD1    1 
ATOM   1847 N ND2    . ASN   E 1 112 ? 271.659 230.861 216.049 1.00 45.64  ? 124 ASN   B ND2    1 
ATOM   1848 N N      . ASN   E 1 113 ? 273.981 230.964 221.564 1.00 45.81  ? 125 ASN   B N      1 
ATOM   1849 C CA     . ASN   E 1 113 ? 273.787 230.735 222.994 1.00 45.89  ? 125 ASN   B CA     1 
ATOM   1850 C C      . ASN   E 1 113 ? 272.948 229.488 223.256 1.00 46.72  ? 125 ASN   B C      1 
ATOM   1851 O O      . ASN   E 1 113 ? 272.130 229.450 224.177 1.00 53.47  ? 125 ASN   B O      1 
ATOM   1852 C CB     . ASN   E 1 113 ? 273.161 231.960 223.661 1.00 48.84  ? 125 ASN   B CB     1 
ATOM   1853 C CG     . ASN   E 1 113 ? 274.030 233.191 223.542 1.00 49.21  ? 125 ASN   B CG     1 
ATOM   1854 O OD1    . ASN   E 1 113 ? 275.081 233.161 222.907 1.00 49.17  ? 125 ASN   B OD1    1 
ATOM   1855 N ND2    . ASN   E 1 113 ? 273.591 234.287 224.148 1.00 49.27  ? 125 ASN   B ND2    1 
ATOM   1856 N N      . GLY   E 1 114 ? 273.152 228.457 222.441 1.00 43.04  ? 126 GLY   B N      1 
ATOM   1857 C CA     . GLY   E 1 114 ? 272.539 227.169 222.685 1.00 42.86  ? 126 GLY   B CA     1 
ATOM   1858 C C      . GLY   E 1 114 ? 271.099 227.024 222.252 1.00 44.96  ? 126 GLY   B C      1 
ATOM   1859 O O      . GLY   E 1 114 ? 270.500 225.973 222.507 1.00 51.70  ? 126 GLY   B O      1 
ATOM   1860 N N      . ASP   E 1 115 ? 270.519 228.029 221.609 1.00 42.20  ? 127 ASP   B N      1 
ATOM   1861 C CA     . ASP   E 1 115 ? 269.150 227.936 221.126 1.00 43.67  ? 127 ASP   B CA     1 
ATOM   1862 C C      . ASP   E 1 115 ? 269.126 227.704 219.620 1.00 46.29  ? 127 ASP   B C      1 
ATOM   1863 O O      . ASP   E 1 115 ? 270.069 228.047 218.904 1.00 49.26  ? 127 ASP   B O      1 
ATOM   1864 C CB     . ASP   E 1 115 ? 268.345 229.186 221.509 1.00 44.56  ? 127 ASP   B CB     1 
ATOM   1865 C CG     . ASP   E 1 115 ? 268.745 230.428 220.729 1.00 52.57  ? 127 ASP   B CG     1 
ATOM   1866 O OD1    . ASP   E 1 115 ? 268.394 231.534 221.188 1.00 59.50  ? 127 ASP   B OD1    1 
ATOM   1867 O OD2    . ASP   E 1 115 ? 269.409 230.326 219.679 1.00 58.07  ? 127 ASP   B OD2    1 
ATOM   1868 N N      . ASP   E 1 116 ? 268.040 227.090 219.149 1.00 44.44  ? 128 ASP   B N      1 
ATOM   1869 C CA     . ASP   E 1 116 ? 267.948 226.732 217.738 1.00 43.55  ? 128 ASP   B CA     1 
ATOM   1870 C C      . ASP   E 1 116 ? 268.018 227.968 216.851 1.00 42.08  ? 128 ASP   B C      1 
ATOM   1871 O O      . ASP   E 1 116 ? 268.765 227.999 215.866 1.00 46.49  ? 128 ASP   B O      1 
ATOM   1872 C CB     . ASP   E 1 116 ? 266.658 225.953 217.482 1.00 42.22  ? 128 ASP   B CB     1 
ATOM   1873 C CG     . ASP   E 1 116 ? 266.725 224.532 218.001 1.00 44.96  ? 128 ASP   B CG     1 
ATOM   1874 O OD1    . ASP   E 1 116 ? 267.621 223.782 217.567 1.00 49.22  ? 128 ASP   B OD1    1 
ATOM   1875 O OD2    . ASP   E 1 116 ? 265.882 224.164 218.844 1.00 42.43  ? 128 ASP   B OD2    1 
ATOM   1876 N N      . ALA   E 1 117 ? 267.254 229.001 217.190 1.00 37.99  ? 129 ALA   B N      1 
ATOM   1877 C CA     . ALA   E 1 117 ? 267.253 230.258 216.448 1.00 36.20  ? 129 ALA   B CA     1 
ATOM   1878 C C      . ALA   E 1 117 ? 266.960 230.022 214.967 1.00 39.55  ? 129 ALA   B C      1 
ATOM   1879 O O      . ALA   E 1 117 ? 267.782 230.282 214.088 1.00 41.30  ? 129 ALA   B O      1 
ATOM   1880 C CB     . ALA   E 1 117 ? 268.576 231.001 216.636 1.00 39.48  ? 129 ALA   B CB     1 
ATOM   1881 N N      . THR   E 1 118 ? 265.759 229.511 214.701 1.00 38.54  ? 130 THR   B N      1 
ATOM   1882 C CA     . THR   E 1 118 ? 265.319 229.334 213.324 1.00 38.78  ? 130 THR   B CA     1 
ATOM   1883 C C      . THR   E 1 118 ? 265.089 230.658 212.608 1.00 38.70  ? 130 THR   B C      1 
ATOM   1884 O O      . THR   E 1 118 ? 265.000 230.668 211.376 1.00 36.91  ? 130 THR   B O      1 
ATOM   1885 C CB     . THR   E 1 118 ? 264.043 228.493 213.282 1.00 39.65  ? 130 THR   B CB     1 
ATOM   1886 O OG1    . THR   E 1 118 ? 262.917 229.309 213.625 1.00 45.93  ? 130 THR   B OG1    1 
ATOM   1887 C CG2    . THR   E 1 118 ? 264.140 227.332 214.254 1.00 33.52  ? 130 THR   B CG2    1 
ATOM   1888 N N      . ALA   E 1 119 ? 264.994 231.767 213.343 1.00 39.80  ? 131 ALA   B N      1 
ATOM   1889 C CA     . ALA   E 1 119 ? 264.855 233.069 212.703 1.00 38.28  ? 131 ALA   B CA     1 
ATOM   1890 C C      . ALA   E 1 119 ? 266.088 233.411 211.878 1.00 36.02  ? 131 ALA   B C      1 
ATOM   1891 O O      . ALA   E 1 119 ? 265.977 233.999 210.796 1.00 35.17  ? 131 ALA   B O      1 
ATOM   1892 C CB     . ALA   E 1 119 ? 264.595 234.146 213.756 1.00 41.04  ? 131 ALA   B CB     1 
ATOM   1893 N N      . GLY   E 1 120 ? 267.274 233.065 212.378 1.00 35.59  ? 132 GLY   B N      1 
ATOM   1894 C CA     . GLY   E 1 120 ? 268.482 233.290 211.604 1.00 35.45  ? 132 GLY   B CA     1 
ATOM   1895 C C      . GLY   E 1 120 ? 268.520 232.462 210.335 1.00 37.38  ? 132 GLY   B C      1 
ATOM   1896 O O      . GLY   E 1 120 ? 268.987 232.926 209.292 1.00 36.37  ? 132 GLY   B O      1 
ATOM   1897 N N      . LEU   E 1 121 ? 268.043 231.218 210.410 1.00 39.45  ? 133 LEU   B N      1 
ATOM   1898 C CA     . LEU   E 1 121 ? 267.992 230.369 209.226 1.00 39.04  ? 133 LEU   B CA     1 
ATOM   1899 C C      . LEU   E 1 121 ? 267.011 230.915 208.197 1.00 37.66  ? 133 LEU   B C      1 
ATOM   1900 O O      . LEU   E 1 121 ? 267.320 230.973 207.002 1.00 39.75  ? 133 LEU   B O      1 
ATOM   1901 C CB     . LEU   E 1 121 ? 267.616 228.943 209.626 1.00 39.86  ? 133 LEU   B CB     1 
ATOM   1902 C CG     . LEU   E 1 121 ? 268.551 228.258 210.621 1.00 37.18  ? 133 LEU   B CG     1 
ATOM   1903 C CD1    . LEU   E 1 121 ? 268.058 226.861 210.941 1.00 43.30  ? 133 LEU   B CD1    1 
ATOM   1904 C CD2    . LEU   E 1 121 ? 269.959 228.211 210.068 1.00 38.89  ? 133 LEU   B CD2    1 
ATOM   1905 N N      . THR   E 1 122 ? 265.821 231.324 208.642 1.00 36.70  ? 134 THR   B N      1 
ATOM   1906 C CA     . THR   E 1 122 ? 264.850 231.898 207.718 1.00 38.63  ? 134 THR   B CA     1 
ATOM   1907 C C      . THR   E 1 122 ? 265.370 233.187 207.101 1.00 37.14  ? 134 THR   B C      1 
ATOM   1908 O O      . THR   E 1 122 ? 265.059 233.490 205.944 1.00 37.77  ? 134 THR   B O      1 
ATOM   1909 C CB     . THR   E 1 122 ? 263.522 232.153 208.431 1.00 39.86  ? 134 THR   B CB     1 
ATOM   1910 O OG1    . THR   E 1 122 ? 263.116 230.970 209.129 1.00 42.71  ? 134 THR   B OG1    1 
ATOM   1911 C CG2    . THR   E 1 122 ? 262.449 232.534 207.430 1.00 42.36  ? 134 THR   B CG2    1 
ATOM   1912 N N      . HIS   E 1 123 ? 266.153 233.957 207.857 1.00 36.35  ? 135 HIS   B N      1 
ATOM   1913 C CA     . HIS   E 1 123 ? 266.759 235.167 207.315 1.00 37.01  ? 135 HIS   B CA     1 
ATOM   1914 C C      . HIS   E 1 123 ? 267.711 234.836 206.173 1.00 38.14  ? 135 HIS   B C      1 
ATOM   1915 O O      . HIS   E 1 123 ? 267.708 235.500 205.130 1.00 39.02  ? 135 HIS   B O      1 
ATOM   1916 C CB     . HIS   E 1 123 ? 267.487 235.916 208.430 1.00 36.22  ? 135 HIS   B CB     1 
ATOM   1917 C CG     . HIS   E 1 123 ? 268.008 237.256 208.023 1.00 36.43  ? 135 HIS   B CG     1 
ATOM   1918 N ND1    . HIS   E 1 123 ? 267.219 238.385 208.000 1.00 40.38  ? 135 HIS   B ND1    1 
ATOM   1919 C CD2    . HIS   E 1 123 ? 269.243 237.652 207.634 1.00 36.25  ? 135 HIS   B CD2    1 
ATOM   1920 C CE1    . HIS   E 1 123 ? 267.944 239.418 207.610 1.00 43.55  ? 135 HIS   B CE1    1 
ATOM   1921 N NE2    . HIS   E 1 123 ? 269.175 239.000 207.380 1.00 41.94  ? 135 HIS   B NE2    1 
ATOM   1922 N N      . MET   E 1 124 ? 268.537 233.804 206.352 1.00 37.88  ? 136 MET   B N      1 
ATOM   1923 C CA     . MET   E 1 124 ? 269.446 233.395 205.287 1.00 38.99  ? 136 MET   B CA     1 
ATOM   1924 C C      . MET   E 1 124 ? 268.680 232.835 204.095 1.00 38.33  ? 136 MET   B C      1 
ATOM   1925 O O      . MET   E 1 124 ? 269.072 233.048 202.943 1.00 40.29  ? 136 MET   B O      1 
ATOM   1926 C CB     . MET   E 1 124 ? 270.452 232.374 205.816 1.00 37.71  ? 136 MET   B CB     1 
ATOM   1927 C CG     . MET   E 1 124 ? 271.642 232.993 206.529 1.00 37.69  ? 136 MET   B CG     1 
ATOM   1928 S SD     . MET   E 1 124 ? 272.530 231.827 207.577 1.00 53.14  ? 136 MET   B SD     1 
ATOM   1929 C CE     . MET   E 1 124 ? 271.197 230.763 208.110 1.00 45.09  ? 136 MET   B CE     1 
ATOM   1930 N N      . MET   E 1 125 ? 267.589 232.111 204.352 1.00 38.62  ? 137 MET   B N      1 
ATOM   1931 C CA     . MET   E 1 125 ? 266.772 231.595 203.259 1.00 37.47  ? 137 MET   B CA     1 
ATOM   1932 C C      . MET   E 1 125 ? 266.128 232.727 202.469 1.00 39.55  ? 137 MET   B C      1 
ATOM   1933 O O      . MET   E 1 125 ? 265.998 232.642 201.243 1.00 40.39  ? 137 MET   B O      1 
ATOM   1934 C CB     . MET   E 1 125 ? 265.713 230.636 203.804 1.00 36.97  ? 137 MET   B CB     1 
ATOM   1935 C CG     . MET   E 1 125 ? 266.269 229.272 204.184 1.00 42.84  ? 137 MET   B CG     1 
ATOM   1936 S SD     . MET   E 1 125 ? 265.096 228.219 205.053 1.00 53.21  ? 137 MET   B SD     1 
ATOM   1937 C CE     . MET   E 1 125 ? 263.674 229.295 205.119 1.00 45.42  ? 137 MET   B CE     1 
ATOM   1938 N N      . ILE   E 1 126 ? 265.712 233.794 203.153 1.00 42.71  ? 138 ILE   B N      1 
ATOM   1939 C CA     . ILE   E 1 126 ? 265.170 234.955 202.454 1.00 41.00  ? 138 ILE   B CA     1 
ATOM   1940 C C      . ILE   E 1 126 ? 266.246 235.610 201.598 1.00 39.89  ? 138 ILE   B C      1 
ATOM   1941 O O      . ILE   E 1 126 ? 265.983 236.046 200.472 1.00 40.59  ? 138 ILE   B O      1 
ATOM   1942 C CB     . ILE   E 1 126 ? 264.557 235.948 203.457 1.00 39.89  ? 138 ILE   B CB     1 
ATOM   1943 C CG1    . ILE   E 1 126 ? 263.319 235.341 204.114 1.00 42.17  ? 138 ILE   B CG1    1 
ATOM   1944 C CG2    . ILE   E 1 126 ? 264.202 237.251 202.768 1.00 43.98  ? 138 ILE   B CG2    1 
ATOM   1945 C CD1    . ILE   E 1 126 ? 262.939 236.002 205.412 1.00 42.46  ? 138 ILE   B CD1    1 
ATOM   1946 N N      . TRP   E 1 127 ? 267.474 235.689 202.116 1.00 40.04  ? 139 TRP   B N      1 
ATOM   1947 C CA     . TRP   E 1 127 ? 268.570 236.260 201.340 1.00 40.74  ? 139 TRP   B CA     1 
ATOM   1948 C C      . TRP   E 1 127 ? 268.815 235.461 200.066 1.00 40.10  ? 139 TRP   B C      1 
ATOM   1949 O O      . TRP   E 1 127 ? 269.001 236.037 198.988 1.00 39.20  ? 139 TRP   B O      1 
ATOM   1950 C CB     . TRP   E 1 127 ? 269.831 236.327 202.203 1.00 38.59  ? 139 TRP   B CB     1 
ATOM   1951 C CG     . TRP   E 1 127 ? 271.117 236.115 201.462 1.00 38.84  ? 139 TRP   B CG     1 
ATOM   1952 C CD1    . TRP   E 1 127 ? 272.009 235.102 201.647 1.00 40.21  ? 139 TRP   B CD1    1 
ATOM   1953 C CD2    . TRP   E 1 127 ? 271.663 236.946 200.432 1.00 39.89  ? 139 TRP   B CD2    1 
ATOM   1954 N NE1    . TRP   E 1 127 ? 273.073 235.244 200.792 1.00 38.29  ? 139 TRP   B NE1    1 
ATOM   1955 C CE2    . TRP   E 1 127 ? 272.885 236.369 200.034 1.00 39.17  ? 139 TRP   B CE2    1 
ATOM   1956 C CE3    . TRP   E 1 127 ? 271.236 238.118 199.805 1.00 39.13  ? 139 TRP   B CE3    1 
ATOM   1957 C CZ2    . TRP   E 1 127 ? 273.682 236.924 199.039 1.00 37.77  ? 139 TRP   B CZ2    1 
ATOM   1958 C CZ3    . TRP   E 1 127 ? 272.029 238.667 198.818 1.00 37.59  ? 139 TRP   B CZ3    1 
ATOM   1959 C CH2    . TRP   E 1 127 ? 273.238 238.071 198.444 1.00 38.26  ? 139 TRP   B CH2    1 
ATOM   1960 N N      . HIS   E 1 128 ? 268.810 234.131 200.166 1.00 39.67  ? 140 HIS   B N      1 
ATOM   1961 C CA     . HIS   E 1 128 ? 268.952 233.304 198.973 1.00 38.88  ? 140 HIS   B CA     1 
ATOM   1962 C C      . HIS   E 1 128 ? 267.781 233.507 198.020 1.00 40.57  ? 140 HIS   B C      1 
ATOM   1963 O O      . HIS   E 1 128 ? 267.966 233.563 196.799 1.00 40.61  ? 140 HIS   B O      1 
ATOM   1964 C CB     . HIS   E 1 128 ? 269.076 231.834 199.367 1.00 38.38  ? 140 HIS   B CB     1 
ATOM   1965 C CG     . HIS   E 1 128 ? 270.350 231.505 200.077 1.00 39.59  ? 140 HIS   B CG     1 
ATOM   1966 N ND1    . HIS   E 1 128 ? 270.545 230.316 200.745 1.00 41.95  ? 140 HIS   B ND1    1 
ATOM   1967 C CD2    . HIS   E 1 128 ? 271.498 232.208 200.219 1.00 40.74  ? 140 HIS   B CD2    1 
ATOM   1968 C CE1    . HIS   E 1 128 ? 271.755 230.302 201.272 1.00 41.18  ? 140 HIS   B CE1    1 
ATOM   1969 N NE2    . HIS   E 1 128 ? 272.354 231.439 200.968 1.00 44.53  ? 140 HIS   B NE2    1 
ATOM   1970 N N      . SER   E 1 129 ? 266.564 233.612 198.560 1.00 40.38  ? 141 SER   B N      1 
ATOM   1971 C CA     . SER   E 1 129 ? 265.396 233.837 197.716 1.00 39.41  ? 141 SER   B CA     1 
ATOM   1972 C C      . SER   E 1 129 ? 265.487 235.172 196.989 1.00 39.31  ? 141 SER   B C      1 
ATOM   1973 O O      . SER   E 1 129 ? 265.153 235.265 195.803 1.00 38.23  ? 141 SER   B O      1 
ATOM   1974 C CB     . SER   E 1 129 ? 264.121 233.771 198.554 1.00 41.01  ? 141 SER   B CB     1 
ATOM   1975 O OG     . SER   E 1 129 ? 263.110 234.593 198.001 1.00 45.90  ? 141 SER   B OG     1 
ATOM   1976 N N      . ASN   E 1 130 ? 265.930 236.220 197.687 1.00 39.58  ? 142 ASN   B N      1 
ATOM   1977 C CA     . ASN   E 1 130 ? 266.091 237.518 197.040 1.00 38.78  ? 142 ASN   B CA     1 
ATOM   1978 C C      . ASN   E 1 130 ? 267.121 237.448 195.922 1.00 36.52  ? 142 ASN   B C      1 
ATOM   1979 O O      . ASN   E 1 130 ? 266.914 238.006 194.839 1.00 35.47  ? 142 ASN   B O      1 
ATOM   1980 C CB     . ASN   E 1 130 ? 266.492 238.574 198.069 1.00 40.24  ? 142 ASN   B CB     1 
ATOM   1981 C CG     . ASN   E 1 130 ? 265.352 238.963 198.984 1.00 43.10  ? 142 ASN   B CG     1 
ATOM   1982 O OD1    . ASN   E 1 130 ? 264.204 238.583 198.762 1.00 47.28  ? 142 ASN   B OD1    1 
ATOM   1983 N ND2    . ASN   E 1 130 ? 265.663 239.729 200.020 1.00 42.28  ? 142 ASN   B ND2    1 
ATOM   1984 N N      . LEU   E 1 131 ? 268.242 236.768 196.168 1.00 37.77  ? 143 LEU   B N      1 
ATOM   1985 C CA     . LEU   E 1 131 ? 269.261 236.620 195.136 1.00 38.26  ? 143 LEU   B CA     1 
ATOM   1986 C C      . LEU   E 1 131 ? 268.728 235.834 193.944 1.00 37.03  ? 143 LEU   B C      1 
ATOM   1987 O O      . LEU   E 1 131 ? 269.000 236.182 192.790 1.00 34.26  ? 143 LEU   B O      1 
ATOM   1988 C CB     . LEU   E 1 131 ? 270.498 235.941 195.722 1.00 38.86  ? 143 LEU   B CB     1 
ATOM   1989 C CG     . LEU   E 1 131 ? 271.687 235.739 194.784 1.00 36.80  ? 143 LEU   B CG     1 
ATOM   1990 C CD1    . LEU   E 1 131 ? 272.094 237.054 194.149 1.00 39.43  ? 143 LEU   B CD1    1 
ATOM   1991 C CD2    . LEU   E 1 131 ? 272.851 235.122 195.534 1.00 36.85  ? 143 LEU   B CD2    1 
ATOM   1992 N N      . ASN   E 1 132 ? 267.970 234.767 194.204 1.00 40.06  ? 144 ASN   B N      1 
ATOM   1993 C CA     . ASN   E 1 132 ? 267.378 233.997 193.115 1.00 39.60  ? 144 ASN   B CA     1 
ATOM   1994 C C      . ASN   E 1 132 ? 266.393 234.840 192.315 1.00 38.37  ? 144 ASN   B C      1 
ATOM   1995 O O      . ASN   E 1 132 ? 266.356 234.762 191.082 1.00 38.81  ? 144 ASN   B O      1 
ATOM   1996 C CB     . ASN   E 1 132 ? 266.686 232.750 193.666 1.00 40.11  ? 144 ASN   B CB     1 
ATOM   1997 C CG     . ASN   E 1 132 ? 267.659 231.640 194.000 1.00 43.39  ? 144 ASN   B CG     1 
ATOM   1998 O OD1    . ASN   E 1 132 ? 267.621 231.076 195.091 1.00 50.14  ? 144 ASN   B OD1    1 
ATOM   1999 N ND2    . ASN   E 1 132 ? 268.533 231.315 193.056 1.00 43.70  ? 144 ASN   B ND2    1 
ATOM   2000 N N      . ASP   E 1 133 ? 265.584 235.649 193.000 1.00 39.90  ? 145 ASP   B N      1 
ATOM   2001 C CA     . ASP   E 1 133 ? 264.599 236.471 192.307 1.00 39.79  ? 145 ASP   B CA     1 
ATOM   2002 C C      . ASP   E 1 133 ? 265.269 237.498 191.405 1.00 39.82  ? 145 ASP   B C      1 
ATOM   2003 O O      . ASP   E 1 133 ? 264.800 237.755 190.291 1.00 42.14  ? 145 ASP   B O      1 
ATOM   2004 C CB     . ASP   E 1 133 ? 263.688 237.162 193.320 1.00 39.54  ? 145 ASP   B CB     1 
ATOM   2005 C CG     . ASP   E 1 133 ? 262.710 236.208 193.971 1.00 43.03  ? 145 ASP   B CG     1 
ATOM   2006 O OD1    . ASP   E 1 133 ? 262.319 235.218 193.320 1.00 45.93  ? 145 ASP   B OD1    1 
ATOM   2007 O OD2    . ASP   E 1 133 ? 262.330 236.447 195.134 1.00 45.63  ? 145 ASP   B OD2    1 
ATOM   2008 N N      . ALA   E 1 134 ? 266.363 238.102 191.870 1.00 36.47  ? 146 ALA   B N      1 
ATOM   2009 C CA     . ALA   E 1 134 ? 267.033 239.125 191.078 1.00 37.15  ? 146 ALA   B CA     1 
ATOM   2010 C C      . ALA   E 1 134 ? 267.827 238.525 189.925 1.00 39.94  ? 146 ALA   B C      1 
ATOM   2011 O O      . ALA   E 1 134 ? 268.081 239.210 188.929 1.00 45.21  ? 146 ALA   B O      1 
ATOM   2012 C CB     . ALA   E 1 134 ? 267.949 239.964 191.967 1.00 37.22  ? 146 ALA   B CB     1 
ATOM   2013 N N      . THR   E 1 135 ? 268.224 237.258 190.035 1.00 38.10  ? 147 THR   B N      1 
ATOM   2014 C CA     . THR   E 1 135 ? 269.092 236.629 189.046 1.00 38.02  ? 147 THR   B CA     1 
ATOM   2015 C C      . THR   E 1 135 ? 268.313 235.787 188.041 1.00 38.65  ? 147 THR   B C      1 
ATOM   2016 O O      . THR   E 1 135 ? 268.424 236.000 186.830 1.00 40.64  ? 147 THR   B O      1 
ATOM   2017 C CB     . THR   E 1 135 ? 270.150 235.767 189.748 1.00 38.01  ? 147 THR   B CB     1 
ATOM   2018 O OG1    . THR   E 1 135 ? 270.936 236.586 190.620 1.00 42.95  ? 147 THR   B OG1    1 
ATOM   2019 C CG2    . THR   E 1 135 ? 271.060 235.114 188.729 1.00 37.29  ? 147 THR   B CG2    1 
ATOM   2020 N N      . TYR   E 1 136 ? 267.520 234.835 188.522 1.00 40.52  ? 148 TYR   B N      1 
ATOM   2021 C CA     . TYR   E 1 136 ? 266.869 233.851 187.670 1.00 40.45  ? 148 TYR   B CA     1 
ATOM   2022 C C      . TYR   E 1 136 ? 265.370 234.106 187.595 1.00 40.45  ? 148 TYR   B C      1 
ATOM   2023 O O      . TYR   E 1 136 ? 264.741 234.484 188.587 1.00 37.32  ? 148 TYR   B O      1 
ATOM   2024 C CB     . TYR   E 1 136 ? 267.135 232.432 188.178 1.00 38.91  ? 148 TYR   B CB     1 
ATOM   2025 C CG     . TYR   E 1 136 ? 268.597 232.053 188.163 1.00 38.07  ? 148 TYR   B CG     1 
ATOM   2026 C CD1    . TYR   E 1 136 ? 269.316 232.036 186.979 1.00 41.34  ? 148 TYR   B CD1    1 
ATOM   2027 C CD2    . TYR   E 1 136 ? 269.258 231.717 189.334 1.00 37.43  ? 148 TYR   B CD2    1 
ATOM   2028 C CE1    . TYR   E 1 136 ? 270.653 231.694 186.959 1.00 43.22  ? 148 TYR   B CE1    1 
ATOM   2029 C CE2    . TYR   E 1 136 ? 270.595 231.372 189.324 1.00 37.35  ? 148 TYR   B CE2    1 
ATOM   2030 C CZ     . TYR   E 1 136 ? 271.287 231.362 188.134 1.00 38.62  ? 148 TYR   B CZ     1 
ATOM   2031 O OH     . TYR   E 1 136 ? 272.619 231.019 188.118 1.00 34.85  ? 148 TYR   B OH     1 
ATOM   2032 N N      . GLN   E 1 137 ? 264.810 233.897 186.408 1.00 40.46  ? 149 GLN   B N      1 
ATOM   2033 C CA     . GLN   E 1 137 ? 263.396 234.109 186.128 1.00 39.28  ? 149 GLN   B CA     1 
ATOM   2034 C C      . GLN   E 1 137 ? 262.754 232.753 185.867 1.00 42.60  ? 149 GLN   B C      1 
ATOM   2035 O O      . GLN   E 1 137 ? 263.150 232.048 184.934 1.00 50.87  ? 149 GLN   B O      1 
ATOM   2036 C CB     . GLN   E 1 137 ? 263.229 235.033 184.923 1.00 38.15  ? 149 GLN   B CB     1 
ATOM   2037 C CG     . GLN   E 1 137 ? 261.809 235.238 184.452 1.00 39.50  ? 149 GLN   B CG     1 
ATOM   2038 C CD     . GLN   E 1 137 ? 261.702 236.366 183.447 1.00 42.57  ? 149 GLN   B CD     1 
ATOM   2039 O OE1    . GLN   E 1 137 ? 262.698 236.996 183.094 1.00 34.84  ? 149 GLN   B OE1    1 
ATOM   2040 N NE2    . GLN   E 1 137 ? 260.489 236.625 182.978 1.00 50.53  ? 149 GLN   B NE2    1 
ATOM   2041 N N      . ARG   E 1 138 ? 261.770 232.387 186.689 1.00 39.65  ? 150 ARG   B N      1 
ATOM   2042 C CA     . ARG   E 1 138 ? 261.156 231.062 186.606 1.00 43.56  ? 150 ARG   B CA     1 
ATOM   2043 C C      . ARG   E 1 138 ? 259.828 231.159 185.860 1.00 43.34  ? 150 ARG   B C      1 
ATOM   2044 O O      . ARG   E 1 138 ? 258.746 231.098 186.441 1.00 45.69  ? 150 ARG   B O      1 
ATOM   2045 C CB     . ARG   E 1 138 ? 260.985 230.460 187.997 1.00 44.55  ? 150 ARG   B CB     1 
ATOM   2046 C CG     . ARG   E 1 138 ? 260.597 231.446 189.075 1.00 40.71  ? 150 ARG   B CG     1 
ATOM   2047 C CD     . ARG   E 1 138 ? 260.857 230.852 190.444 1.00 44.23  ? 150 ARG   B CD     1 
ATOM   2048 N NE     . ARG   E 1 138 ? 259.983 229.720 190.727 1.00 47.58  ? 150 ARG   B NE     1 
ATOM   2049 C CZ     . ARG   E 1 138 ? 260.372 228.452 190.702 1.00 46.36  ? 150 ARG   B CZ     1 
ATOM   2050 N NH1    . ARG   E 1 138 ? 261.610 228.116 190.387 1.00 46.17  ? 150 ARG   B NH1    1 
ATOM   2051 N NH2    . ARG   E 1 138 ? 259.494 227.499 191.000 1.00 45.86  ? 150 ARG   B NH2    1 
ATOM   2052 N N      . THR   E 1 139 ? 259.925 231.303 184.539 1.00 42.98  ? 151 THR   B N      1 
ATOM   2053 C CA     . THR   E 1 139 ? 258.741 231.244 183.694 1.00 45.78  ? 151 THR   B CA     1 
ATOM   2054 C C      . THR   E 1 139 ? 258.294 229.816 183.428 1.00 46.24  ? 151 THR   B C      1 
ATOM   2055 O O      . THR   E 1 139 ? 257.113 229.588 183.146 1.00 46.76  ? 151 THR   B O      1 
ATOM   2056 C CB     . THR   E 1 139 ? 259.000 231.952 182.364 1.00 48.86  ? 151 THR   B CB     1 
ATOM   2057 O OG1    . THR   E 1 139 ? 257.964 231.618 181.434 1.00 50.31  ? 151 THR   B OG1    1 
ATOM   2058 C CG2    . THR   E 1 139 ? 260.339 231.527 181.790 1.00 49.22  ? 151 THR   B CG2    1 
ATOM   2059 N N      . ARG   E 1 140 ? 259.213 228.855 183.516 1.00 47.24  ? 152 ARG   B N      1 
ATOM   2060 C CA     . ARG   E 1 140 ? 258.869 227.463 183.256 1.00 47.27  ? 152 ARG   B CA     1 
ATOM   2061 C C      . ARG   E 1 140 ? 257.894 226.933 184.299 1.00 43.91  ? 152 ARG   B C      1 
ATOM   2062 O O      . ARG   E 1 140 ? 256.980 226.168 183.972 1.00 44.88  ? 152 ARG   B O      1 
ATOM   2063 C CB     . ARG   E 1 140 ? 260.144 226.624 183.216 1.00 48.00  ? 152 ARG   B CB     1 
ATOM   2064 C CG     . ARG   E 1 140 ? 259.941 225.135 183.358 1.00 57.27  ? 152 ARG   B CG     1 
ATOM   2065 C CD     . ARG   E 1 140 ? 261.289 224.446 183.414 1.00 62.07  ? 152 ARG   B CD     1 
ATOM   2066 N NE     . ARG   E 1 140 ? 262.115 224.812 182.270 1.00 62.59  ? 152 ARG   B NE     1 
ATOM   2067 C CZ     . ARG   E 1 140 ? 263.074 225.727 182.304 1.00 52.16  ? 152 ARG   B CZ     1 
ATOM   2068 N NH1    . ARG   E 1 140 ? 263.352 226.394 183.410 1.00 42.51  ? 152 ARG   B NH1    1 
ATOM   2069 N NH2    . ARG   E 1 140 ? 263.769 225.980 181.199 1.00 58.65  ? 152 ARG   B NH2    1 
ATOM   2070 N N      . ALA   E 1 141 ? 258.077 227.320 185.562 1.00 43.72  ? 153 ALA   B N      1 
ATOM   2071 C CA     . ALA   E 1 141 ? 257.125 226.929 186.594 1.00 46.15  ? 153 ALA   B CA     1 
ATOM   2072 C C      . ALA   E 1 141 ? 255.787 227.633 186.419 1.00 46.35  ? 153 ALA   B C      1 
ATOM   2073 O O      . ALA   E 1 141 ? 254.740 227.055 186.729 1.00 45.26  ? 153 ALA   B O      1 
ATOM   2074 C CB     . ALA   E 1 141 ? 257.701 227.218 187.979 1.00 44.79  ? 153 ALA   B CB     1 
ATOM   2075 N N      . LEU   E 1 142 ? 255.801 228.874 185.930 1.00 45.98  ? 154 LEU   B N      1 
ATOM   2076 C CA     . LEU   E 1 142 ? 254.555 229.603 185.711 1.00 44.52  ? 154 LEU   B CA     1 
ATOM   2077 C C      . LEU   E 1 142 ? 253.705 228.933 184.641 1.00 43.50  ? 154 LEU   B C      1 
ATOM   2078 O O      . LEU   E 1 142 ? 252.494 228.756 184.815 1.00 43.50  ? 154 LEU   B O      1 
ATOM   2079 C CB     . LEU   E 1 142 ? 254.860 231.049 185.321 1.00 44.08  ? 154 LEU   B CB     1 
ATOM   2080 C CG     . LEU   E 1 142 ? 255.143 232.030 186.455 1.00 47.76  ? 154 LEU   B CG     1 
ATOM   2081 C CD1    . LEU   E 1 142 ? 255.781 233.295 185.915 1.00 49.73  ? 154 LEU   B CD1    1 
ATOM   2082 C CD2    . LEU   E 1 142 ? 253.868 232.354 187.192 1.00 49.20  ? 154 LEU   B CD2    1 
ATOM   2083 N N      . VAL   E 1 143 ? 254.322 228.560 183.518 1.00 44.33  ? 155 VAL   B N      1 
ATOM   2084 C CA     . VAL   E 1 143 ? 253.579 227.914 182.443 1.00 43.96  ? 155 VAL   B CA     1 
ATOM   2085 C C      . VAL   E 1 143 ? 253.161 226.507 182.845 1.00 44.37  ? 155 VAL   B C      1 
ATOM   2086 O O      . VAL   E 1 143 ? 252.058 226.058 182.509 1.00 47.73  ? 155 VAL   B O      1 
ATOM   2087 C CB     . VAL   E 1 143 ? 254.413 227.907 181.148 1.00 42.07  ? 155 VAL   B CB     1 
ATOM   2088 C CG1    . VAL   E 1 143 ? 255.698 227.127 181.349 1.00 40.42  ? 155 VAL   B CG1    1 
ATOM   2089 C CG2    . VAL   E 1 143 ? 253.609 227.323 180.002 1.00 43.20  ? 155 VAL   B CG2    1 
ATOM   2090 N N      . ARG   E 1 144 ? 254.024 225.790 183.562 1.00 43.67  ? 156 ARG   B N      1 
ATOM   2091 C CA     . ARG   E 1 144 ? 253.727 224.405 183.908 1.00 43.99  ? 156 ARG   B CA     1 
ATOM   2092 C C      . ARG   E 1 144 ? 252.518 224.317 184.832 1.00 45.73  ? 156 ARG   B C      1 
ATOM   2093 O O      . ARG   E 1 144 ? 251.777 223.329 184.802 1.00 50.97  ? 156 ARG   B O      1 
ATOM   2094 C CB     . ARG   E 1 144 ? 254.959 223.760 184.540 1.00 45.76  ? 156 ARG   B CB     1 
ATOM   2095 C CG     . ARG   E 1 144 ? 254.721 222.427 185.210 1.00 50.61  ? 156 ARG   B CG     1 
ATOM   2096 C CD     . ARG   E 1 144 ? 256.004 221.936 185.859 1.00 57.55  ? 156 ARG   B CD     1 
ATOM   2097 N NE     . ARG   E 1 144 ? 256.905 221.316 184.896 1.00 55.96  ? 156 ARG   B NE     1 
ATOM   2098 C CZ     . ARG   E 1 144 ? 256.783 220.077 184.442 1.00 68.62  ? 156 ARG   B CZ     1 
ATOM   2099 N NH1    . ARG   E 1 144 ? 255.805 219.285 184.850 1.00 74.18  ? 156 ARG   B NH1    1 
ATOM   2100 N NH2    . ARG   E 1 144 ? 257.665 219.620 183.559 1.00 74.63  ? 156 ARG   B NH2    1 
ATOM   2101 N N      . THR   E 1 145 ? 252.303 225.340 185.659 1.00 44.67  ? 157 THR   B N      1 
ATOM   2102 C CA     . THR   E 1 145 ? 251.112 225.407 186.496 1.00 44.32  ? 157 THR   B CA     1 
ATOM   2103 C C      . THR   E 1 145 ? 249.926 226.051 185.791 1.00 45.32  ? 157 THR   B C      1 
ATOM   2104 O O      . THR   E 1 145 ? 248.841 226.116 186.377 1.00 47.85  ? 157 THR   B O      1 
ATOM   2105 C CB     . THR   E 1 145 ? 251.407 226.175 187.786 1.00 44.72  ? 157 THR   B CB     1 
ATOM   2106 O OG1    . THR   E 1 145 ? 251.926 227.471 187.465 1.00 48.00  ? 157 THR   B OG1    1 
ATOM   2107 C CG2    . THR   E 1 145 ? 252.420 225.425 188.631 1.00 50.29  ? 157 THR   B CG2    1 
ATOM   2108 N N      . GLY   E 1 146 ? 250.103 226.531 184.564 1.00 45.30  ? 158 GLY   B N      1 
ATOM   2109 C CA     . GLY   E 1 146 ? 249.027 227.138 183.812 1.00 44.62  ? 158 GLY   B CA     1 
ATOM   2110 C C      . GLY   E 1 146 ? 248.902 228.637 183.961 1.00 45.37  ? 158 GLY   B C      1 
ATOM   2111 O O      . GLY   E 1 146 ? 247.963 229.219 183.408 1.00 47.47  ? 158 GLY   B O      1 
ATOM   2112 N N      . MET   E 1 147 ? 249.814 229.279 184.679 1.00 47.74  ? 159 MET   B N      1 
ATOM   2113 C CA     . MET   E 1 147 ? 249.737 230.712 184.904 1.00 43.62  ? 159 MET   B CA     1 
ATOM   2114 C C      . MET   E 1 147 ? 250.453 231.458 183.787 1.00 45.01  ? 159 MET   B C      1 
ATOM   2115 O O      . MET   E 1 147 ? 251.414 230.960 183.195 1.00 48.43  ? 159 MET   B O      1 
ATOM   2116 C CB     . MET   E 1 147 ? 250.340 231.079 186.261 1.00 43.78  ? 159 MET   B CB     1 
ATOM   2117 C CG     . MET   E 1 147 ? 249.418 230.778 187.429 1.00 45.76  ? 159 MET   B CG     1 
ATOM   2118 S SD     . MET   E 1 147 ? 250.152 231.046 189.051 1.00 52.62  ? 159 MET   B SD     1 
ATOM   2119 C CE     . MET   E 1 147 ? 251.200 232.454 188.723 1.00 47.41  ? 159 MET   B CE     1 
ATOM   2120 N N      . ASP   E 1 148 ? 249.966 232.651 183.494 1.00 46.72  ? 160 ASP   B N      1 
ATOM   2121 C CA     . ASP   E 1 148 ? 250.525 233.431 182.400 1.00 46.00  ? 160 ASP   B CA     1 
ATOM   2122 C C      . ASP   E 1 148 ? 251.947 233.858 182.750 1.00 43.69  ? 160 ASP   B C      1 
ATOM   2123 O O      . ASP   E 1 148 ? 252.174 234.412 183.830 1.00 46.00  ? 160 ASP   B O      1 
ATOM   2124 C CB     . ASP   E 1 148 ? 249.642 234.646 182.122 1.00 41.54  ? 160 ASP   B CB     1 
ATOM   2125 C CG     . ASP   E 1 148 ? 250.347 235.714 181.323 1.00 47.96  ? 160 ASP   B CG     1 
ATOM   2126 O OD1    . ASP   E 1 148 ? 251.198 235.367 180.478 1.00 53.90  ? 160 ASP   B OD1    1 
ATOM   2127 O OD2    . ASP   E 1 148 ? 250.044 236.905 181.533 1.00 52.23  ? 160 ASP   B OD2    1 
ATOM   2128 N N      . PRO   E 1 149 ? 252.928 233.613 181.876 1.00 45.49  ? 161 PRO   B N      1 
ATOM   2129 C CA     . PRO   E 1 149 ? 254.320 233.952 182.203 1.00 46.67  ? 161 PRO   B CA     1 
ATOM   2130 C C      . PRO   E 1 149 ? 254.582 235.441 182.356 1.00 46.82  ? 161 PRO   B C      1 
ATOM   2131 O O      . PRO   E 1 149 ? 255.707 235.819 182.699 1.00 48.86  ? 161 PRO   B O      1 
ATOM   2132 C CB     . PRO   E 1 149 ? 255.107 233.377 181.015 1.00 46.32  ? 161 PRO   B CB     1 
ATOM   2133 C CG     . PRO   E 1 149 ? 254.110 233.269 179.915 1.00 45.35  ? 161 PRO   B CG     1 
ATOM   2134 C CD     . PRO   E 1 149 ? 252.818 232.927 180.579 1.00 47.06  ? 161 PRO   B CD     1 
ATOM   2135 N N      . ARG   E 1 150 ? 253.591 236.298 182.114 1.00 46.51  ? 162 ARG   B N      1 
ATOM   2136 C CA     . ARG   E 1 150 ? 253.797 237.734 182.232 1.00 44.56  ? 162 ARG   B CA     1 
ATOM   2137 C C      . ARG   E 1 150 ? 253.729 238.232 183.670 1.00 46.10  ? 162 ARG   B C      1 
ATOM   2138 O O      . ARG   E 1 150 ? 254.188 239.345 183.942 1.00 50.85  ? 162 ARG   B O      1 
ATOM   2139 C CB     . ARG   E 1 150 ? 252.768 238.481 181.384 1.00 43.91  ? 162 ARG   B CB     1 
ATOM   2140 C CG     . ARG   E 1 150 ? 253.284 238.888 180.021 1.00 46.83  ? 162 ARG   B CG     1 
ATOM   2141 C CD     . ARG   E 1 150 ? 252.868 237.880 178.969 1.00 48.77  ? 162 ARG   B CD     1 
ATOM   2142 N NE     . ARG   E 1 150 ? 251.451 237.986 178.646 1.00 45.60  ? 162 ARG   B NE     1 
ATOM   2143 C CZ     . ARG   E 1 150 ? 250.914 238.995 177.977 1.00 51.08  ? 162 ARG   B CZ     1 
ATOM   2144 N NH1    . ARG   E 1 150 ? 251.650 240.002 177.538 1.00 52.01  ? 162 ARG   B NH1    1 
ATOM   2145 N NH2    . ARG   E 1 150 ? 249.606 238.993 177.740 1.00 54.36  ? 162 ARG   B NH2    1 
ATOM   2146 N N      . MET   E 1 151 ? 253.168 237.450 184.593 1.00 44.32  ? 163 MET   B N      1 
ATOM   2147 C CA     . MET   E 1 151 ? 253.022 237.900 185.978 1.00 46.44  ? 163 MET   B CA     1 
ATOM   2148 C C      . MET   E 1 151 ? 254.266 237.522 186.782 1.00 45.87  ? 163 MET   B C      1 
ATOM   2149 O O      . MET   E 1 151 ? 254.213 236.848 187.811 1.00 42.90  ? 163 MET   B O      1 
ATOM   2150 C CB     . MET   E 1 151 ? 251.753 237.331 186.602 1.00 45.68  ? 163 MET   B CB     1 
ATOM   2151 C CG     . MET   E 1 151 ? 251.307 235.992 186.056 1.00 48.01  ? 163 MET   B CG     1 
ATOM   2152 S SD     . MET   E 1 151 ? 249.520 235.779 186.183 1.00 48.89  ? 163 MET   B SD     1 
ATOM   2153 C CE     . MET   E 1 151 ? 248.954 236.841 184.859 1.00 44.62  ? 163 MET   B CE     1 
ATOM   2154 N N      . CYS   E 1 152 ? 255.408 237.999 186.294 1.00 50.71  ? 164 CYS   B N      1 
ATOM   2155 C CA     . CYS   E 1 152 ? 256.675 237.792 186.979 1.00 48.64  ? 164 CYS   B CA     1 
ATOM   2156 C C      . CYS   E 1 152 ? 256.905 238.792 188.102 1.00 47.73  ? 164 CYS   B C      1 
ATOM   2157 O O      . CYS   E 1 152 ? 257.783 238.567 188.939 1.00 51.49  ? 164 CYS   B O      1 
ATOM   2158 C CB     . CYS   E 1 152 ? 257.836 237.863 185.980 1.00 44.17  ? 164 CYS   B CB     1 
ATOM   2159 S SG     . CYS   E 1 152 ? 258.506 239.516 185.722 1.00 71.39  ? 164 CYS   B SG     1 
ATOM   2160 N N      . SER   E 1 153 ? 256.128 239.874 188.151 1.00 45.21  ? 165 SER   B N      1 
ATOM   2161 C CA     . SER   E 1 153 ? 256.222 240.833 189.242 1.00 42.72  ? 165 SER   B CA     1 
ATOM   2162 C C      . SER   E 1 153 ? 255.670 240.290 190.551 1.00 43.19  ? 165 SER   B C      1 
ATOM   2163 O O      . SER   E 1 153 ? 255.975 240.846 191.611 1.00 44.36  ? 165 SER   B O      1 
ATOM   2164 C CB     . SER   E 1 153 ? 255.481 242.118 188.873 1.00 43.34  ? 165 SER   B CB     1 
ATOM   2165 O OG     . SER   E 1 153 ? 256.177 242.835 187.869 1.00 57.68  ? 165 SER   B OG     1 
ATOM   2166 N N      . LEU   E 1 154 ? 254.872 239.225 190.500 1.00 43.39  ? 166 LEU   B N      1 
ATOM   2167 C CA     . LEU   E 1 154 ? 254.264 238.626 191.678 1.00 39.51  ? 166 LEU   B CA     1 
ATOM   2168 C C      . LEU   E 1 154 ? 255.007 237.380 192.144 1.00 42.60  ? 166 LEU   B C      1 
ATOM   2169 O O      . LEU   E 1 154 ? 254.534 236.686 193.049 1.00 44.61  ? 166 LEU   B O      1 
ATOM   2170 C CB     . LEU   E 1 154 ? 252.800 238.292 191.395 1.00 39.69  ? 166 LEU   B CB     1 
ATOM   2171 C CG     . LEU   E 1 154 ? 251.889 239.492 191.135 1.00 38.26  ? 166 LEU   B CG     1 
ATOM   2172 C CD1    . LEU   E 1 154 ? 250.506 239.031 190.723 1.00 39.25  ? 166 LEU   B CD1    1 
ATOM   2173 C CD2    . LEU   E 1 154 ? 251.816 240.386 192.358 1.00 38.91  ? 166 LEU   B CD2    1 
ATOM   2174 N N      . MET   E 1 155 ? 256.163 237.089 191.548 1.00 45.00  ? 167 MET   B N      1 
ATOM   2175 C CA     . MET   E 1 155 ? 256.922 235.876 191.818 1.00 45.65  ? 167 MET   B CA     1 
ATOM   2176 C C      . MET   E 1 155 ? 257.887 236.039 192.985 1.00 47.63  ? 167 MET   B C      1 
ATOM   2177 O O      . MET   E 1 155 ? 258.883 235.314 193.063 1.00 49.75  ? 167 MET   B O      1 
ATOM   2178 C CB     . MET   E 1 155 ? 257.694 235.451 190.567 1.00 48.30  ? 167 MET   B CB     1 
ATOM   2179 C CG     . MET   E 1 155 ? 256.870 234.770 189.486 1.00 52.76  ? 167 MET   B CG     1 
ATOM   2180 S SD     . MET   E 1 155 ? 255.984 233.300 190.035 1.00 63.67  ? 167 MET   B SD     1 
ATOM   2181 C CE     . MET   E 1 155 ? 254.613 234.039 190.906 1.00 42.38  ? 167 MET   B CE     1 
ATOM   2182 N N      . GLN   E 1 156 ? 257.617 236.975 193.888 1.00 45.05  ? 168 GLN   B N      1 
ATOM   2183 C CA     . GLN   E 1 156 ? 258.536 237.236 194.986 1.00 43.68  ? 168 GLN   B CA     1 
ATOM   2184 C C      . GLN   E 1 156 ? 258.548 236.057 195.952 1.00 41.68  ? 168 GLN   B C      1 
ATOM   2185 O O      . GLN   E 1 156 ? 257.500 235.638 196.453 1.00 41.74  ? 168 GLN   B O      1 
ATOM   2186 C CB     . GLN   E 1 156 ? 258.136 238.519 195.711 1.00 43.09  ? 168 GLN   B CB     1 
ATOM   2187 C CG     . GLN   E 1 156 ? 258.678 238.635 197.119 1.00 45.06  ? 168 GLN   B CG     1 
ATOM   2188 C CD     . GLN   E 1 156 ? 259.879 239.549 197.201 1.00 44.60  ? 168 GLN   B CD     1 
ATOM   2189 O OE1    . GLN   E 1 156 ? 260.692 239.607 196.281 1.00 49.93  ? 168 GLN   B OE1    1 
ATOM   2190 N NE2    . GLN   E 1 156 ? 259.998 240.268 198.307 1.00 43.63  ? 168 GLN   B NE2    1 
ATOM   2191 N N      . GLY   E 1 157 ? 259.738 235.529 196.217 1.00 42.63  ? 169 GLY   B N      1 
ATOM   2192 C CA     . GLY   E 1 157 ? 259.893 234.398 197.114 1.00 41.50  ? 169 GLY   B CA     1 
ATOM   2193 C C      . GLY   E 1 157 ? 259.301 233.097 196.615 1.00 42.10  ? 169 GLY   B C      1 
ATOM   2194 O O      . GLY   E 1 157 ? 258.802 232.300 197.419 1.00 40.12  ? 169 GLY   B O      1 
ATOM   2195 N N      . SER   E 1 158 ? 259.356 232.851 195.306 1.00 45.55  ? 170 SER   B N      1 
ATOM   2196 C CA     . SER   E 1 158 ? 258.881 231.584 194.769 1.00 43.89  ? 170 SER   B CA     1 
ATOM   2197 C C      . SER   E 1 158 ? 259.838 230.435 195.052 1.00 45.22  ? 170 SER   B C      1 
ATOM   2198 O O      . SER   E 1 158 ? 259.424 229.274 195.000 1.00 47.85  ? 170 SER   B O      1 
ATOM   2199 C CB     . SER   E 1 158 ? 258.649 231.698 193.262 1.00 44.11  ? 170 SER   B CB     1 
ATOM   2200 O OG     . SER   E 1 158 ? 259.630 232.519 192.656 1.00 51.92  ? 170 SER   B OG     1 
ATOM   2201 N N      . THR   E 1 159 ? 261.099 230.731 195.349 1.00 44.64  ? 171 THR   B N      1 
ATOM   2202 C CA     . THR   E 1 159 ? 262.088 229.712 195.670 1.00 43.44  ? 171 THR   B CA     1 
ATOM   2203 C C      . THR   E 1 159 ? 262.221 229.462 197.166 1.00 42.98  ? 171 THR   B C      1 
ATOM   2204 O O      . THR   E 1 159 ? 263.100 228.700 197.576 1.00 45.72  ? 171 THR   B O      1 
ATOM   2205 C CB     . THR   E 1 159 ? 263.450 230.101 195.092 1.00 47.42  ? 171 THR   B CB     1 
ATOM   2206 O OG1    . THR   E 1 159 ? 263.753 231.453 195.455 1.00 49.90  ? 171 THR   B OG1    1 
ATOM   2207 C CG2    . THR   E 1 159 ? 263.435 229.981 193.580 1.00 46.37  ? 171 THR   B CG2    1 
ATOM   2208 N N      . LEU   E 1 160 ? 261.385 230.084 197.982 1.00 43.92  ? 172 LEU   B N      1 
ATOM   2209 C CA     . LEU   E 1 160 ? 261.454 229.878 199.422 1.00 41.64  ? 172 LEU   B CA     1 
ATOM   2210 C C      . LEU   E 1 160 ? 260.926 228.493 199.780 1.00 44.87  ? 172 LEU   B C      1 
ATOM   2211 O O      . LEU   E 1 160 ? 259.817 228.133 199.371 1.00 49.21  ? 172 LEU   B O      1 
ATOM   2212 C CB     . LEU   E 1 160 ? 260.650 230.952 200.150 1.00 38.77  ? 172 LEU   B CB     1 
ATOM   2213 C CG     . LEU   E 1 160 ? 261.424 232.173 200.643 1.00 37.77  ? 172 LEU   B CG     1 
ATOM   2214 C CD1    . LEU   E 1 160 ? 260.470 233.297 201.000 1.00 40.85  ? 172 LEU   B CD1    1 
ATOM   2215 C CD2    . LEU   E 1 160 ? 262.285 231.806 201.834 1.00 42.72  ? 172 LEU   B CD2    1 
ATOM   2216 N N      . PRO   E 1 161 ? 261.680 227.692 200.526 1.00 44.40  ? 173 PRO   B N      1 
ATOM   2217 C CA     . PRO   E 1 161 ? 261.171 226.385 200.947 1.00 47.69  ? 173 PRO   B CA     1 
ATOM   2218 C C      . PRO   E 1 161 ? 260.043 226.532 201.957 1.00 44.65  ? 173 PRO   B C      1 
ATOM   2219 O O      . PRO   E 1 161 ? 259.895 227.558 202.624 1.00 46.57  ? 173 PRO   B O      1 
ATOM   2220 C CB     . PRO   E 1 161 ? 262.393 225.706 201.573 1.00 46.55  ? 173 PRO   B CB     1 
ATOM   2221 C CG     . PRO   E 1 161 ? 263.292 226.821 201.965 1.00 41.45  ? 173 PRO   B CG     1 
ATOM   2222 C CD     . PRO   E 1 161 ? 263.050 227.943 201.003 1.00 40.48  ? 173 PRO   B CD     1 
ATOM   2223 N N      . ARG   E 1 162 ? 259.236 225.474 202.062 1.00 38.86  ? 174 ARG   B N      1 
ATOM   2224 C CA     . ARG   E 1 162 ? 258.104 225.493 202.981 1.00 42.15  ? 174 ARG   B CA     1 
ATOM   2225 C C      . ARG   E 1 162 ? 258.532 225.653 204.434 1.00 43.85  ? 174 ARG   B C      1 
ATOM   2226 O O      . ARG   E 1 162 ? 257.703 226.029 205.268 1.00 43.96  ? 174 ARG   B O      1 
ATOM   2227 C CB     . ARG   E 1 162 ? 257.271 224.218 202.817 1.00 42.62  ? 174 ARG   B CB     1 
ATOM   2228 C CG     . ARG   E 1 162 ? 256.416 223.874 204.025 1.00 51.81  ? 174 ARG   B CG     1 
ATOM   2229 C CD     . ARG   E 1 162 ? 256.185 222.376 204.151 1.00 55.69  ? 174 ARG   B CD     1 
ATOM   2230 N NE     . ARG   E 1 162 ? 256.075 221.711 202.858 1.00 49.29  ? 174 ARG   B NE     1 
ATOM   2231 C CZ     . ARG   E 1 162 ? 255.162 221.998 201.942 1.00 49.63  ? 174 ARG   B CZ     1 
ATOM   2232 N NH1    . ARG   E 1 162 ? 254.245 222.929 202.147 1.00 46.40  ? 174 ARG   B NH1    1 
ATOM   2233 N NH2    . ARG   E 1 162 ? 255.162 221.329 200.794 1.00 55.64  ? 174 ARG   B NH2    1 
ATOM   2234 N N      . ARG   E 1 163 ? 259.801 225.396 204.750 1.00 43.07  ? 175 ARG   B N      1 
ATOM   2235 C CA     . ARG   E 1 163 ? 260.279 225.538 206.120 1.00 42.74  ? 175 ARG   B CA     1 
ATOM   2236 C C      . ARG   E 1 163 ? 260.154 226.965 206.633 1.00 46.80  ? 175 ARG   B C      1 
ATOM   2237 O O      . ARG   E 1 163 ? 260.107 227.172 207.849 1.00 51.70  ? 175 ARG   B O      1 
ATOM   2238 C CB     . ARG   E 1 163 ? 261.733 225.074 206.206 1.00 44.01  ? 175 ARG   B CB     1 
ATOM   2239 C CG     . ARG   E 1 163 ? 261.954 223.679 205.657 1.00 46.34  ? 175 ARG   B CG     1 
ATOM   2240 C CD     . ARG   E 1 163 ? 263.303 223.548 204.975 1.00 44.10  ? 175 ARG   B CD     1 
ATOM   2241 N NE     . ARG   E 1 163 ? 264.400 224.001 205.818 1.00 42.28  ? 175 ARG   B NE     1 
ATOM   2242 C CZ     . ARG   E 1 163 ? 265.642 224.182 205.391 1.00 45.60  ? 175 ARG   B CZ     1 
ATOM   2243 N NH1    . ARG   E 1 163 ? 265.978 223.967 204.130 1.00 41.41  ? 175 ARG   B NH1    1 
ATOM   2244 N NH2    . ARG   E 1 163 ? 266.569 224.592 206.250 1.00 49.87  ? 175 ARG   B NH2    1 
ATOM   2245 N N      . SER   E 1 164 ? 260.099 227.951 205.740 1.00 45.66  ? 176 SER   B N      1 
ATOM   2246 C CA     . SER   E 1 164 ? 259.994 229.355 206.132 1.00 44.29  ? 176 SER   B CA     1 
ATOM   2247 C C      . SER   E 1 164 ? 258.520 229.711 206.263 1.00 48.71  ? 176 SER   B C      1 
ATOM   2248 O O      . SER   E 1 164 ? 257.873 230.142 205.310 1.00 54.32  ? 176 SER   B O      1 
ATOM   2249 C CB     . SER   E 1 164 ? 260.695 230.249 205.118 1.00 43.94  ? 176 SER   B CB     1 
ATOM   2250 O OG     . SER   E 1 164 ? 260.251 229.966 203.805 1.00 42.95  ? 176 SER   B OG     1 
ATOM   2251 N N      . GLY   E 1 165 ? 257.982 229.528 207.461 1.00 46.69  ? 177 GLY   B N      1 
ATOM   2252 C CA     . GLY   E 1 165 ? 256.608 229.879 207.752 1.00 47.07  ? 177 GLY   B CA     1 
ATOM   2253 C C      . GLY   E 1 165 ? 256.524 231.246 208.403 1.00 48.00  ? 177 GLY   B C      1 
ATOM   2254 O O      . GLY   E 1 165 ? 257.471 231.709 209.031 1.00 51.34  ? 177 GLY   B O      1 
ATOM   2255 N N      . ALA   E 1 166 ? 255.371 231.892 208.246 1.00 43.33  ? 178 ALA   B N      1 
ATOM   2256 C CA     . ALA   E 1 166 ? 255.190 233.221 208.811 1.00 46.98  ? 178 ALA   B CA     1 
ATOM   2257 C C      . ALA   E 1 166 ? 256.206 234.187 208.218 1.00 49.41  ? 178 ALA   B C      1 
ATOM   2258 O O      . ALA   E 1 166 ? 255.876 234.972 207.324 1.00 53.52  ? 178 ALA   B O      1 
ATOM   2259 C CB     . ALA   E 1 166 ? 255.312 233.181 210.335 1.00 53.76  ? 178 ALA   B CB     1 
ATOM   2260 N N      . ALA   E 1 167 ? 257.443 234.140 208.717 1.00 45.57  ? 179 ALA   B N      1 
ATOM   2261 C CA     . ALA   E 1 167 ? 258.475 235.047 208.226 1.00 45.12  ? 179 ALA   B CA     1 
ATOM   2262 C C      . ALA   E 1 167 ? 258.645 234.921 206.718 1.00 43.80  ? 179 ALA   B C      1 
ATOM   2263 O O      . ALA   E 1 167 ? 258.682 235.926 205.999 1.00 42.68  ? 179 ALA   B O      1 
ATOM   2264 C CB     . ALA   E 1 167 ? 259.795 234.772 208.943 1.00 49.16  ? 179 ALA   B CB     1 
ATOM   2265 N N      . GLY   E 1 168 ? 258.757 233.690 206.221 1.00 43.75  ? 180 GLY   B N      1 
ATOM   2266 C CA     . GLY   E 1 168 ? 258.850 233.491 204.785 1.00 45.55  ? 180 GLY   B CA     1 
ATOM   2267 C C      . GLY   E 1 168 ? 257.565 233.839 204.061 1.00 44.93  ? 180 GLY   B C      1 
ATOM   2268 O O      . GLY   E 1 168 ? 257.590 234.429 202.979 1.00 46.54  ? 180 GLY   B O      1 
ATOM   2269 N N      . ALA   E 1 169 ? 256.422 233.477 204.647 1.00 44.54  ? 181 ALA   B N      1 
ATOM   2270 C CA     . ALA   E 1 169 ? 255.142 233.732 203.995 1.00 43.33  ? 181 ALA   B CA     1 
ATOM   2271 C C      . ALA   E 1 169 ? 254.855 235.221 203.874 1.00 42.94  ? 181 ALA   B C      1 
ATOM   2272 O O      . ALA   E 1 169 ? 254.238 235.654 202.894 1.00 45.20  ? 181 ALA   B O      1 
ATOM   2273 C CB     . ALA   E 1 169 ? 254.017 233.035 204.758 1.00 44.09  ? 181 ALA   B CB     1 
ATOM   2274 N N      . ALA   E 1 170 ? 255.284 236.018 204.853 1.00 41.72  ? 182 ALA   B N      1 
ATOM   2275 C CA     . ALA   E 1 170 ? 255.056 237.457 204.783 1.00 39.35  ? 182 ALA   B CA     1 
ATOM   2276 C C      . ALA   E 1 170 ? 255.790 238.076 203.602 1.00 41.01  ? 182 ALA   B C      1 
ATOM   2277 O O      . ALA   E 1 170 ? 255.268 238.986 202.948 1.00 41.70  ? 182 ALA   B O      1 
ATOM   2278 C CB     . ALA   E 1 170 ? 255.490 238.121 206.089 1.00 37.04  ? 182 ALA   B CB     1 
ATOM   2279 N N      . VAL   E 1 171 ? 257.003 237.598 203.313 1.00 41.62  ? 183 VAL   B N      1 
ATOM   2280 C CA     . VAL   E 1 171 ? 257.813 238.191 202.252 1.00 41.81  ? 183 VAL   B CA     1 
ATOM   2281 C C      . VAL   E 1 171 ? 257.463 237.671 200.869 1.00 41.28  ? 183 VAL   B C      1 
ATOM   2282 O O      . VAL   E 1 171 ? 257.835 238.302 199.873 1.00 42.11  ? 183 VAL   B O      1 
ATOM   2283 C CB     . VAL   E 1 171 ? 259.311 237.952 202.510 1.00 40.11  ? 183 VAL   B CB     1 
ATOM   2284 C CG1    . VAL   E 1 171 ? 260.135 238.463 201.345 1.00 39.16  ? 183 VAL   B CG1    1 
ATOM   2285 C CG2    . VAL   E 1 171 ? 259.738 238.622 203.803 1.00 43.05  ? 183 VAL   B CG2    1 
ATOM   2286 N N      . LYS   E 1 172 ? 256.762 236.549 200.772 1.00 40.60  ? 184 LYS   B N      1 
ATOM   2287 C CA     . LYS   E 1 172 ? 256.402 236.000 199.476 1.00 40.18  ? 184 LYS   B CA     1 
ATOM   2288 C C      . LYS   E 1 172 ? 255.163 236.704 198.927 1.00 40.49  ? 184 LYS   B C      1 
ATOM   2289 O O      . LYS   E 1 172 ? 254.337 237.240 199.667 1.00 42.81  ? 184 LYS   B O      1 
ATOM   2290 C CB     . LYS   E 1 172 ? 256.190 234.489 199.582 1.00 39.03  ? 184 LYS   B CB     1 
ATOM   2291 C CG     . LYS   E 1 172 ? 254.800 234.062 199.988 1.00 42.60  ? 184 LYS   B CG     1 
ATOM   2292 C CD     . LYS   E 1 172 ? 254.827 232.667 200.593 1.00 44.96  ? 184 LYS   B CD     1 
ATOM   2293 C CE     . LYS   E 1 172 ? 255.906 231.806 199.961 1.00 37.54  ? 184 LYS   B CE     1 
ATOM   2294 N NZ     . LYS   E 1 172 ? 256.061 230.509 200.672 1.00 32.87  ? 184 LYS   B NZ     1 
ATOM   2295 N N      . GLY   E 1 173 ? 255.039 236.693 197.601 1.00 41.73  ? 185 GLY   B N      1 
ATOM   2296 C CA     . GLY   E 1 173 ? 254.079 237.515 196.904 1.00 39.52  ? 185 GLY   B CA     1 
ATOM   2297 C C      . GLY   E 1 173 ? 252.822 236.761 196.500 1.00 40.83  ? 185 GLY   B C      1 
ATOM   2298 O O      . GLY   E 1 173 ? 252.668 235.563 196.727 1.00 42.59  ? 185 GLY   B O      1 
ATOM   2299 N N      . VAL   E 1 174 ? 251.908 237.512 195.885 1.00 40.18  ? 186 VAL   B N      1 
ATOM   2300 C CA     . VAL   E 1 174 ? 250.621 236.951 195.493 1.00 39.35  ? 186 VAL   B CA     1 
ATOM   2301 C C      . VAL   E 1 174 ? 250.804 235.848 194.460 1.00 41.65  ? 186 VAL   B C      1 
ATOM   2302 O O      . VAL   E 1 174 ? 250.176 234.786 194.550 1.00 45.64  ? 186 VAL   B O      1 
ATOM   2303 C CB     . VAL   E 1 174 ? 249.693 238.062 194.974 1.00 36.28  ? 186 VAL   B CB     1 
ATOM   2304 C CG1    . VAL   E 1 174 ? 248.336 237.488 194.613 1.00 39.50  ? 186 VAL   B CG1    1 
ATOM   2305 C CG2    . VAL   E 1 174 ? 249.560 239.161 196.010 1.00 38.47  ? 186 VAL   B CG2    1 
ATOM   2306 N N      . GLY   E 1 175 ? 251.662 236.074 193.465 1.00 38.49  ? 187 GLY   B N      1 
ATOM   2307 C CA     . GLY   E 1 175 ? 251.846 235.076 192.428 1.00 38.20  ? 187 GLY   B CA     1 
ATOM   2308 C C      . GLY   E 1 175 ? 252.375 233.759 192.956 1.00 39.52  ? 187 GLY   B C      1 
ATOM   2309 O O      . GLY   E 1 175 ? 251.903 232.692 192.557 1.00 41.60  ? 187 GLY   B O      1 
ATOM   2310 N N      . THR   E 1 176 ? 253.364 233.811 193.851 1.00 40.43  ? 188 THR   B N      1 
ATOM   2311 C CA     . THR   E 1 176 ? 253.896 232.584 194.434 1.00 41.63  ? 188 THR   B CA     1 
ATOM   2312 C C      . THR   E 1 176 ? 252.843 231.877 195.271 1.00 41.91  ? 188 THR   B C      1 
ATOM   2313 O O      . THR   E 1 176 ? 252.762 230.643 195.271 1.00 45.02  ? 188 THR   B O      1 
ATOM   2314 C CB     . THR   E 1 176 ? 255.129 232.888 195.283 1.00 42.43  ? 188 THR   B CB     1 
ATOM   2315 O OG1    . THR   E 1 176 ? 254.720 233.284 196.597 1.00 44.01  ? 188 THR   B OG1    1 
ATOM   2316 C CG2    . THR   E 1 176 ? 255.942 233.999 194.655 1.00 45.11  ? 188 THR   B CG2    1 
ATOM   2317 N N      . MET   E 1 177 ? 252.040 232.645 196.008 1.00 41.78  ? 189 MET   B N      1 
ATOM   2318 C CA     . MET   E 1 177 ? 250.995 232.053 196.833 1.00 41.17  ? 189 MET   B CA     1 
ATOM   2319 C C      . MET   E 1 177 ? 249.970 231.340 195.967 1.00 41.04  ? 189 MET   B C      1 
ATOM   2320 O O      . MET   E 1 177 ? 249.546 230.221 196.278 1.00 43.61  ? 189 MET   B O      1 
ATOM   2321 C CB     . MET   E 1 177 ? 250.330 233.137 197.678 1.00 39.81  ? 189 MET   B CB     1 
ATOM   2322 C CG     . MET   E 1 177 ? 251.183 233.554 198.842 1.00 41.06  ? 189 MET   B CG     1 
ATOM   2323 S SD     . MET   E 1 177 ? 251.274 232.303 200.122 1.00 58.64  ? 189 MET   B SD     1 
ATOM   2324 C CE     . MET   E 1 177 ? 251.326 233.348 201.566 1.00 49.89  ? 189 MET   B CE     1 
ATOM   2325 N N      . VAL   E 1 178 ? 249.582 231.967 194.856 1.00 38.85  ? 190 VAL   B N      1 
ATOM   2326 C CA     . VAL   E 1 178 ? 248.609 231.363 193.953 1.00 40.67  ? 190 VAL   B CA     1 
ATOM   2327 C C      . VAL   E 1 178 ? 249.165 230.084 193.341 1.00 41.08  ? 190 VAL   B C      1 
ATOM   2328 O O      . VAL   E 1 178 ? 248.438 229.102 193.155 1.00 44.04  ? 190 VAL   B O      1 
ATOM   2329 C CB     . VAL   E 1 178 ? 248.189 232.374 192.872 1.00 41.46  ? 190 VAL   B CB     1 
ATOM   2330 C CG1    . VAL   E 1 178 ? 247.349 231.689 191.819 1.00 41.99  ? 190 VAL   B CG1    1 
ATOM   2331 C CG2    . VAL   E 1 178 ? 247.424 233.521 193.500 1.00 39.43  ? 190 VAL   B CG2    1 
ATOM   2332 N N      . MET   E 1 179 ? 250.457 230.076 193.009 1.00 40.13  ? 191 MET   B N      1 
ATOM   2333 C CA     . MET   E 1 179 ? 251.069 228.870 192.462 1.00 40.35  ? 191 MET   B CA     1 
ATOM   2334 C C      . MET   E 1 179 ? 250.999 227.718 193.456 1.00 42.01  ? 191 MET   B C      1 
ATOM   2335 O O      . MET   E 1 179 ? 250.789 226.565 193.065 1.00 42.26  ? 191 MET   B O      1 
ATOM   2336 C CB     . MET   E 1 179 ? 252.519 229.152 192.064 1.00 41.53  ? 191 MET   B CB     1 
ATOM   2337 C CG     . MET   E 1 179 ? 253.072 228.207 191.014 1.00 44.35  ? 191 MET   B CG     1 
ATOM   2338 S SD     . MET   E 1 179 ? 254.832 228.436 190.686 1.00 57.43  ? 191 MET   B SD     1 
ATOM   2339 C CE     . MET   E 1 179 ? 255.018 230.183 191.013 1.00 45.74  ? 191 MET   B CE     1 
ATOM   2340 N N      . GLU   E 1 180 ? 251.185 228.008 194.745 1.00 43.77  ? 192 GLU   B N      1 
ATOM   2341 C CA     . GLU   E 1 180 ? 251.066 226.971 195.763 1.00 43.67  ? 192 GLU   B CA     1 
ATOM   2342 C C      . GLU   E 1 180 ? 249.649 226.415 195.813 1.00 41.93  ? 192 GLU   B C      1 
ATOM   2343 O O      . GLU   E 1 180 ? 249.448 225.200 195.915 1.00 40.45  ? 192 GLU   B O      1 
ATOM   2344 C CB     . GLU   E 1 180 ? 251.473 227.529 197.125 1.00 43.60  ? 192 GLU   B CB     1 
ATOM   2345 C CG     . GLU   E 1 180 ? 252.901 228.024 197.189 1.00 50.41  ? 192 GLU   B CG     1 
ATOM   2346 C CD     . GLU   E 1 180 ? 253.443 228.028 198.598 1.00 64.86  ? 192 GLU   B CD     1 
ATOM   2347 O OE1    . GLU   E 1 180 ? 252.628 228.023 199.542 1.00 65.54  ? 192 GLU   B OE1    1 
ATOM   2348 O OE2    . GLU   E 1 180 ? 254.680 228.040 198.764 1.00 75.28  ? 192 GLU   B OE2    1 
ATOM   2349 N N      . LEU   E 1 181 ? 248.650 227.298 195.746 1.00 40.71  ? 193 LEU   B N      1 
ATOM   2350 C CA     . LEU   E 1 181 ? 247.263 226.847 195.729 1.00 41.64  ? 193 LEU   B CA     1 
ATOM   2351 C C      . LEU   E 1 181 ? 246.974 226.000 194.499 1.00 43.31  ? 193 LEU   B C      1 
ATOM   2352 O O      . LEU   E 1 181 ? 246.299 224.969 194.591 1.00 46.40  ? 193 LEU   B O      1 
ATOM   2353 C CB     . LEU   E 1 181 ? 246.317 228.047 195.775 1.00 44.40  ? 193 LEU   B CB     1 
ATOM   2354 C CG     . LEU   E 1 181 ? 246.499 229.057 196.904 1.00 42.06  ? 193 LEU   B CG     1 
ATOM   2355 C CD1    . LEU   E 1 181 ? 245.339 230.030 196.932 1.00 47.14  ? 193 LEU   B CD1    1 
ATOM   2356 C CD2    . LEU   E 1 181 ? 246.588 228.328 198.215 1.00 41.46  ? 193 LEU   B CD2    1 
ATOM   2357 N N      . ILE   E 1 182 ? 247.474 226.421 193.337 1.00 41.45  ? 194 ILE   B N      1 
ATOM   2358 C CA     . ILE   E 1 182 ? 247.174 225.710 192.099 1.00 41.02  ? 194 ILE   B CA     1 
ATOM   2359 C C      . ILE   E 1 182 ? 247.748 224.300 192.140 1.00 43.43  ? 194 ILE   B C      1 
ATOM   2360 O O      . ILE   E 1 182 ? 247.082 223.333 191.752 1.00 44.14  ? 194 ILE   B O      1 
ATOM   2361 C CB     . ILE   E 1 182 ? 247.699 226.503 190.890 1.00 43.15  ? 194 ILE   B CB     1 
ATOM   2362 C CG1    . ILE   E 1 182 ? 246.733 227.634 190.542 1.00 39.77  ? 194 ILE   B CG1    1 
ATOM   2363 C CG2    . ILE   E 1 182 ? 247.893 225.586 189.697 1.00 45.85  ? 194 ILE   B CG2    1 
ATOM   2364 C CD1    . ILE   E 1 182 ? 246.996 228.264 189.200 1.00 44.08  ? 194 ILE   B CD1    1 
ATOM   2365 N N      . ARG   E 1 183 ? 248.988 224.157 192.618 1.00 44.39  ? 195 ARG   B N      1 
ATOM   2366 C CA     . ARG   E 1 183 ? 249.593 222.832 192.694 1.00 44.73  ? 195 ARG   B CA     1 
ATOM   2367 C C      . ARG   E 1 183 ? 248.801 221.922 193.620 1.00 47.42  ? 195 ARG   B C      1 
ATOM   2368 O O      . ARG   E 1 183 ? 248.648 220.726 193.345 1.00 48.99  ? 195 ARG   B O      1 
ATOM   2369 C CB     . ARG   E 1 183 ? 251.046 222.933 193.156 1.00 49.13  ? 195 ARG   B CB     1 
ATOM   2370 C CG     . ARG   E 1 183 ? 251.960 223.658 192.188 1.00 52.42  ? 195 ARG   B CG     1 
ATOM   2371 C CD     . ARG   E 1 183 ? 253.313 223.934 192.821 1.00 53.08  ? 195 ARG   B CD     1 
ATOM   2372 N NE     . ARG   E 1 183 ? 254.270 224.445 191.849 1.00 49.03  ? 195 ARG   B NE     1 
ATOM   2373 C CZ     . ARG   E 1 183 ? 255.030 223.684 191.077 1.00 55.38  ? 195 ARG   B CZ     1 
ATOM   2374 N NH1    . ARG   E 1 183 ? 254.969 222.364 191.133 1.00 59.14  ? 195 ARG   B NH1    1 
ATOM   2375 N NH2    . ARG   E 1 183 ? 255.870 224.260 190.223 1.00 59.47  ? 195 ARG   B NH2    1 
ATOM   2376 N N      . MET   E 1 184 ? 248.289 222.469 194.725 1.00 47.41  ? 196 MET   B N      1 
ATOM   2377 C CA     . MET   E 1 184 ? 247.396 221.696 195.579 1.00 47.97  ? 196 MET   B CA     1 
ATOM   2378 C C      . MET   E 1 184 ? 246.155 221.263 194.813 1.00 47.87  ? 196 MET   B C      1 
ATOM   2379 O O      . MET   E 1 184 ? 245.703 220.120 194.938 1.00 48.15  ? 196 MET   B O      1 
ATOM   2380 C CB     . MET   E 1 184 ? 247.000 222.515 196.806 1.00 46.26  ? 196 MET   B CB     1 
ATOM   2381 C CG     . MET   E 1 184 ? 248.140 222.837 197.747 1.00 43.47  ? 196 MET   B CG     1 
ATOM   2382 S SD     . MET   E 1 184 ? 247.580 223.034 199.448 1.00 52.08  ? 196 MET   B SD     1 
ATOM   2383 C CE     . MET   E 1 184 ? 249.139 222.979 200.321 1.00 55.50  ? 196 MET   B CE     1 
ATOM   2384 N N      . ILE   E 1 185 ? 245.590 222.170 194.014 1.00 46.72  ? 197 ILE   B N      1 
ATOM   2385 C CA     . ILE   E 1 185 ? 244.404 221.845 193.229 1.00 46.85  ? 197 ILE   B CA     1 
ATOM   2386 C C      . ILE   E 1 185 ? 244.719 220.761 192.207 1.00 50.17  ? 197 ILE   B C      1 
ATOM   2387 O O      . ILE   E 1 185 ? 243.948 219.810 192.031 1.00 57.89  ? 197 ILE   B O      1 
ATOM   2388 C CB     . ILE   E 1 185 ? 243.849 223.112 192.553 1.00 49.80  ? 197 ILE   B CB     1 
ATOM   2389 C CG1    . ILE   E 1 185 ? 242.787 223.771 193.433 1.00 44.84  ? 197 ILE   B CG1    1 
ATOM   2390 C CG2    . ILE   E 1 185 ? 243.274 222.777 191.187 1.00 56.46  ? 197 ILE   B CG2    1 
ATOM   2391 C CD1    . ILE   E 1 185 ? 243.340 224.408 194.683 1.00 40.71  ? 197 ILE   B CD1    1 
ATOM   2392 N N      . LYS   E 1 186 ? 245.853 220.884 191.515 1.00 48.06  ? 198 LYS   B N      1 
ATOM   2393 C CA     . LYS   E 1 186 ? 246.192 219.913 190.479 1.00 50.00  ? 198 LYS   B CA     1 
ATOM   2394 C C      . LYS   E 1 186 ? 246.356 218.515 191.059 1.00 53.34  ? 198 LYS   B C      1 
ATOM   2395 O O      . LYS   E 1 186 ? 245.893 217.533 190.469 1.00 58.07  ? 198 LYS   B O      1 
ATOM   2396 C CB     . LYS   E 1 186 ? 247.463 220.343 189.749 1.00 53.26  ? 198 LYS   B CB     1 
ATOM   2397 C CG     . LYS   E 1 186 ? 247.439 221.775 189.250 1.00 51.84  ? 198 LYS   B CG     1 
ATOM   2398 C CD     . LYS   E 1 186 ? 246.451 221.939 188.111 1.00 47.28  ? 198 LYS   B CD     1 
ATOM   2399 C CE     . LYS   E 1 186 ? 246.743 220.967 186.981 1.00 49.93  ? 198 LYS   B CE     1 
ATOM   2400 N NZ     . LYS   E 1 186 ? 248.187 220.611 186.896 1.00 53.38  ? 198 LYS   B NZ     1 
ATOM   2401 N N      . ARG   E 1 187 ? 247.017 218.401 192.212 1.00 50.41  ? 199 ARG   B N      1 
ATOM   2402 C CA     . ARG   E 1 187 ? 247.184 217.090 192.830 1.00 54.57  ? 199 ARG   B CA     1 
ATOM   2403 C C      . ARG   E 1 187 ? 245.842 216.501 193.243 1.00 57.75  ? 199 ARG   B C      1 
ATOM   2404 O O      . ARG   E 1 187 ? 245.638 215.285 193.157 1.00 62.23  ? 199 ARG   B O      1 
ATOM   2405 C CB     . ARG   E 1 187 ? 248.126 217.187 194.027 1.00 57.09  ? 199 ARG   B CB     1 
ATOM   2406 C CG     . ARG   E 1 187 ? 249.432 217.888 193.717 1.00 56.95  ? 199 ARG   B CG     1 
ATOM   2407 C CD     . ARG   E 1 187 ? 250.617 216.977 193.970 1.00 52.83  ? 199 ARG   B CD     1 
ATOM   2408 N NE     . ARG   E 1 187 ? 250.970 216.932 195.383 1.00 61.97  ? 199 ARG   B NE     1 
ATOM   2409 C CZ     . ARG   E 1 187 ? 251.510 217.942 196.049 1.00 70.65  ? 199 ARG   B CZ     1 
ATOM   2410 N NH1    . ARG   E 1 187 ? 251.778 219.095 195.460 1.00 69.84  ? 199 ARG   B NH1    1 
ATOM   2411 N NH2    . ARG   E 1 187 ? 251.789 217.792 197.341 1.00 75.02  ? 199 ARG   B NH2    1 
ATOM   2412 N N      . GLY   E 1 188 ? 244.914 217.345 193.696 1.00 55.43  ? 200 GLY   B N      1 
ATOM   2413 C CA     . GLY   E 1 188 ? 243.585 216.856 194.017 1.00 55.30  ? 200 GLY   B CA     1 
ATOM   2414 C C      . GLY   E 1 188 ? 242.840 216.349 192.798 1.00 59.54  ? 200 GLY   B C      1 
ATOM   2415 O O      . GLY   E 1 188 ? 242.157 215.324 192.858 1.00 68.60  ? 200 GLY   B O      1 
ATOM   2416 N N      . ILE   E 1 189 ? 242.958 217.058 191.675 1.00 54.61  ? 201 ILE   B N      1 
ATOM   2417 C CA     . ILE   E 1 189 ? 242.293 216.623 190.451 1.00 57.78  ? 201 ILE   B CA     1 
ATOM   2418 C C      . ILE   E 1 189 ? 242.894 215.314 189.953 1.00 59.17  ? 201 ILE   B C      1 
ATOM   2419 O O      . ILE   E 1 189 ? 242.175 214.401 189.531 1.00 57.35  ? 201 ILE   B O      1 
ATOM   2420 C CB     . ILE   E 1 189 ? 242.368 217.722 189.376 1.00 59.55  ? 201 ILE   B CB     1 
ATOM   2421 C CG1    . ILE   E 1 189 ? 241.980 219.082 189.959 1.00 53.03  ? 201 ILE   B CG1    1 
ATOM   2422 C CG2    . ILE   E 1 189 ? 241.472 217.377 188.199 1.00 67.26  ? 201 ILE   B CG2    1 
ATOM   2423 C CD1    . ILE   E 1 189 ? 240.902 219.016 191.015 1.00 53.88  ? 201 ILE   B CD1    1 
ATOM   2424 N N      . ASN   E 1 190 ? 244.223 215.207 189.985 1.00 59.71  ? 202 ASN   B N      1 
ATOM   2425 C CA     . ASN   E 1 190 ? 244.878 214.002 189.487 1.00 66.38  ? 202 ASN   B CA     1 
ATOM   2426 C C      . ASN   E 1 190 ? 244.647 212.814 190.413 1.00 69.02  ? 202 ASN   B C      1 
ATOM   2427 O O      . ASN   E 1 190 ? 244.418 211.693 189.946 1.00 68.94  ? 202 ASN   B O      1 
ATOM   2428 C CB     . ASN   E 1 190 ? 246.373 214.257 189.301 1.00 71.18  ? 202 ASN   B CB     1 
ATOM   2429 C CG     . ASN   E 1 190 ? 246.677 215.028 188.034 1.00 76.64  ? 202 ASN   B CG     1 
ATOM   2430 O OD1    . ASN   E 1 190 ? 245.885 215.036 187.093 1.00 72.96  ? 202 ASN   B OD1    1 
ATOM   2431 N ND2    . ASN   E 1 190 ? 247.832 215.682 188.002 1.00 80.37  ? 202 ASN   B ND2    1 
ATOM   2432 N N      . ASP   E 1 191 ? 244.705 213.034 191.723 1.00 69.51  ? 203 ASP   B N      1 
ATOM   2433 C CA     . ASP   E 1 191 ? 244.558 211.971 192.713 1.00 71.75  ? 203 ASP   B CA     1 
ATOM   2434 C C      . ASP   E 1 191 ? 243.212 212.137 193.407 1.00 74.90  ? 203 ASP   B C      1 
ATOM   2435 O O      . ASP   E 1 191 ? 242.973 213.148 194.075 1.00 74.17  ? 203 ASP   B O      1 
ATOM   2436 C CB     . ASP   E 1 191 ? 245.704 212.007 193.722 1.00 74.73  ? 203 ASP   B CB     1 
ATOM   2437 C CG     . ASP   E 1 191 ? 245.326 211.400 195.059 1.00 83.42  ? 203 ASP   B CG     1 
ATOM   2438 O OD1    . ASP   E 1 191 ? 244.560 210.413 195.078 1.00 88.03  ? 203 ASP   B OD1    1 
ATOM   2439 O OD2    . ASP   E 1 191 ? 245.796 211.911 196.096 1.00 85.44  ? 203 ASP   B OD2    1 
ATOM   2440 N N      . ARG   E 1 192 ? 242.340 211.137 193.260 1.00 78.05  ? 204 ARG   B N      1 
ATOM   2441 C CA     . ARG   E 1 192 ? 241.020 211.212 193.877 1.00 85.71  ? 204 ARG   B CA     1 
ATOM   2442 C C      . ARG   E 1 192 ? 241.098 211.085 195.393 1.00 82.64  ? 204 ARG   B C      1 
ATOM   2443 O O      . ARG   E 1 192 ? 240.263 211.653 196.105 1.00 81.38  ? 204 ARG   B O      1 
ATOM   2444 C CB     . ARG   E 1 192 ? 240.108 210.130 193.298 1.00 95.55  ? 204 ARG   B CB     1 
ATOM   2445 C CG     . ARG   E 1 192 ? 239.337 210.565 192.059 1.00 108.58 ? 204 ARG   B CG     1 
ATOM   2446 C CD     . ARG   E 1 192 ? 237.833 210.487 192.275 1.00 126.19 ? 204 ARG   B CD     1 
ATOM   2447 N NE     . ARG   E 1 192 ? 237.095 210.820 191.062 1.00 137.84 ? 204 ARG   B NE     1 
ATOM   2448 C CZ     . ARG   E 1 192 ? 235.871 211.330 191.044 1.00 137.71 ? 204 ARG   B CZ     1 
ATOM   2449 N NH1    . ARG   E 1 192 ? 235.209 211.581 192.162 1.00 135.45 ? 204 ARG   B NH1    1 
ATOM   2450 N NH2    . ARG   E 1 192 ? 235.295 211.595 189.874 1.00 137.32 ? 204 ARG   B NH2    1 
ATOM   2451 N N      . ASN   E 1 193 ? 242.088 210.350 195.902 1.00 84.22  ? 205 ASN   B N      1 
ATOM   2452 C CA     . ASN   E 1 193 ? 242.261 210.187 197.339 1.00 81.08  ? 205 ASN   B CA     1 
ATOM   2453 C C      . ASN   E 1 193 ? 242.560 211.514 198.024 1.00 79.82  ? 205 ASN   B C      1 
ATOM   2454 O O      . ASN   E 1 193 ? 242.218 211.678 199.200 1.00 81.05  ? 205 ASN   B O      1 
ATOM   2455 C CB     . ASN   E 1 193 ? 243.370 209.145 197.577 1.00 87.99  ? 205 ASN   B CB     1 
ATOM   2456 C CG     . ASN   E 1 193 ? 244.099 209.302 198.913 1.00 95.28  ? 205 ASN   B CG     1 
ATOM   2457 O OD1    . ASN   E 1 193 ? 243.640 209.969 199.835 1.00 93.49  ? 205 ASN   B OD1    1 
ATOM   2458 N ND2    . ASN   E 1 193 ? 245.258 208.661 199.012 1.00 98.57  ? 205 ASN   B ND2    1 
ATOM   2459 N N      . PHE   E 1 194 ? 243.126 212.478 197.305 1.00 79.29  ? 206 PHE   B N      1 
ATOM   2460 C CA     . PHE   E 1 194 ? 243.388 213.793 197.869 1.00 71.55  ? 206 PHE   B CA     1 
ATOM   2461 C C      . PHE   E 1 194 ? 242.092 214.423 198.368 1.00 73.60  ? 206 PHE   B C      1 
ATOM   2462 O O      . PHE   E 1 194 ? 241.018 214.228 197.793 1.00 76.61  ? 206 PHE   B O      1 
ATOM   2463 C CB     . PHE   E 1 194 ? 244.038 214.697 196.821 1.00 71.09  ? 206 PHE   B CB     1 
ATOM   2464 C CG     . PHE   E 1 194 ? 245.084 215.623 197.373 1.00 64.73  ? 206 PHE   B CG     1 
ATOM   2465 C CD1    . PHE   E 1 194 ? 246.194 215.125 198.028 1.00 66.58  ? 206 PHE   B CD1    1 
ATOM   2466 C CD2    . PHE   E 1 194 ? 244.965 216.993 197.219 1.00 59.60  ? 206 PHE   B CD2    1 
ATOM   2467 C CE1    . PHE   E 1 194 ? 247.158 215.976 198.529 1.00 66.94  ? 206 PHE   B CE1    1 
ATOM   2468 C CE2    . PHE   E 1 194 ? 245.926 217.847 197.719 1.00 55.07  ? 206 PHE   B CE2    1 
ATOM   2469 C CZ     . PHE   E 1 194 ? 247.023 217.338 198.374 1.00 59.64  ? 206 PHE   B CZ     1 
ATOM   2470 N N      . TRP   E 1 195 ? 242.202 215.188 199.450 1.00 70.47  ? 207 TRP   B N      1 
ATOM   2471 C CA     . TRP   E 1 195 ? 241.047 215.774 200.126 1.00 73.26  ? 207 TRP   B CA     1 
ATOM   2472 C C      . TRP   E 1 195 ? 240.203 214.724 200.833 1.00 82.02  ? 207 TRP   B C      1 
ATOM   2473 O O      . TRP   E 1 195 ? 239.081 215.011 201.261 1.00 88.43  ? 207 TRP   B O      1 
ATOM   2474 C CB     . TRP   E 1 195 ? 240.171 216.570 199.153 1.00 67.69  ? 207 TRP   B CB     1 
ATOM   2475 C CG     . TRP   E 1 195 ? 240.918 217.572 198.347 1.00 65.34  ? 207 TRP   B CG     1 
ATOM   2476 C CD1    . TRP   E 1 195 ? 241.016 217.625 196.989 1.00 66.90  ? 207 TRP   B CD1    1 
ATOM   2477 C CD2    . TRP   E 1 195 ? 241.674 218.676 198.848 1.00 60.20  ? 207 TRP   B CD2    1 
ATOM   2478 N NE1    . TRP   E 1 195 ? 241.790 218.694 196.613 1.00 65.32  ? 207 TRP   B NE1    1 
ATOM   2479 C CE2    . TRP   E 1 195 ? 242.206 219.355 197.737 1.00 61.06  ? 207 TRP   B CE2    1 
ATOM   2480 C CE3    . TRP   E 1 195 ? 241.955 219.154 200.129 1.00 59.60  ? 207 TRP   B CE3    1 
ATOM   2481 C CZ2    . TRP   E 1 195 ? 243.001 220.486 197.868 1.00 61.39  ? 207 TRP   B CZ2    1 
ATOM   2482 C CZ3    . TRP   E 1 195 ? 242.744 220.276 200.256 1.00 60.58  ? 207 TRP   B CZ3    1 
ATOM   2483 C CH2    . TRP   E 1 195 ? 243.258 220.930 199.134 1.00 60.19  ? 207 TRP   B CH2    1 
ATOM   2484 N N      . ARG   E 1 196 ? 240.720 213.505 200.965 1.00 81.24  ? 208 ARG   B N      1 
ATOM   2485 C CA     . ARG   E 1 196 ? 239.987 212.431 201.615 1.00 77.10  ? 208 ARG   B CA     1 
ATOM   2486 C C      . ARG   E 1 196 ? 240.956 211.616 202.457 1.00 78.52  ? 208 ARG   B C      1 
ATOM   2487 O O      . ARG   E 1 196 ? 242.131 211.482 202.106 1.00 83.16  ? 208 ARG   B O      1 
ATOM   2488 C CB     . ARG   E 1 196 ? 239.287 211.533 200.592 1.00 78.38  ? 208 ARG   B CB     1 
ATOM   2489 C CG     . ARG   E 1 196 ? 238.090 210.788 201.141 1.00 80.68  ? 208 ARG   B CG     1 
ATOM   2490 C CD     . ARG   E 1 196 ? 237.271 210.010 200.093 1.00 89.04  ? 208 ARG   B CD     1 
ATOM   2491 N NE     . ARG   E 1 196 ? 238.048 209.231 199.131 1.00 99.67  ? 208 ARG   B NE     1 
ATOM   2492 C CZ     . ARG   E 1 196 ? 238.807 209.729 198.162 1.00 98.82  ? 208 ARG   B CZ     1 
ATOM   2493 N NH1    . ARG   E 1 196 ? 238.839 211.025 197.900 1.00 93.44  ? 208 ARG   B NH1    1 
ATOM   2494 N NH2    . ARG   E 1 196 ? 239.524 208.898 197.410 1.00 95.63  ? 208 ARG   B NH2    1 
ATOM   2495 N N      . GLY   E 1 197 ? 240.459 211.072 203.558 1.00 77.22  ? 209 GLY   B N      1 
ATOM   2496 C CA     . GLY   E 1 197 ? 241.295 210.302 204.453 1.00 77.26  ? 209 GLY   B CA     1 
ATOM   2497 C C      . GLY   E 1 197 ? 241.949 211.161 205.514 1.00 80.43  ? 209 GLY   B C      1 
ATOM   2498 O O      . GLY   E 1 197 ? 241.710 212.366 205.635 1.00 84.14  ? 209 GLY   B O      1 
ATOM   2499 N N      . GLU   E 1 198 ? 242.803 210.511 206.305 1.00 83.59  ? 210 GLU   B N      1 
ATOM   2500 C CA     . GLU   E 1 198 ? 243.509 211.222 207.365 1.00 89.43  ? 210 GLU   B CA     1 
ATOM   2501 C C      . GLU   E 1 198 ? 244.399 212.314 206.789 1.00 85.83  ? 210 GLU   B C      1 
ATOM   2502 O O      . GLU   E 1 198 ? 244.451 213.432 207.314 1.00 85.56  ? 210 GLU   B O      1 
ATOM   2503 C CB     . GLU   E 1 198 ? 244.330 210.238 208.199 1.00 101.32 ? 210 GLU   B CB     1 
ATOM   2504 C CG     . GLU   E 1 198 ? 244.394 210.580 209.678 1.00 109.84 ? 210 GLU   B CG     1 
ATOM   2505 C CD     . GLU   E 1 198 ? 245.539 211.517 210.007 1.00 115.39 ? 210 GLU   B CD     1 
ATOM   2506 O OE1    . GLU   E 1 198 ? 246.393 211.745 209.123 1.00 113.94 ? 210 GLU   B OE1    1 
ATOM   2507 O OE2    . GLU   E 1 198 ? 245.585 212.027 211.146 1.00 117.38 ? 210 GLU   B OE2    1 
ATOM   2508 N N      . ASN   E 1 199 ? 245.108 212.008 205.702 1.00 82.95  ? 211 ASN   B N      1 
ATOM   2509 C CA     . ASN   E 1 199 ? 245.972 213.003 205.078 1.00 81.11  ? 211 ASN   B CA     1 
ATOM   2510 C C      . ASN   E 1 199 ? 245.168 214.134 204.450 1.00 78.26  ? 211 ASN   B C      1 
ATOM   2511 O O      . ASN   E 1 199 ? 245.599 215.291 204.486 1.00 75.96  ? 211 ASN   B O      1 
ATOM   2512 C CB     . ASN   E 1 199 ? 246.865 212.341 204.030 1.00 83.97  ? 211 ASN   B CB     1 
ATOM   2513 C CG     . ASN   E 1 199 ? 248.324 212.713 204.193 1.00 92.41  ? 211 ASN   B CG     1 
ATOM   2514 O OD1    . ASN   E 1 199 ? 248.681 213.504 205.066 1.00 91.06  ? 211 ASN   B OD1    1 
ATOM   2515 N ND2    . ASN   E 1 199 ? 249.179 212.142 203.352 1.00 97.40  ? 211 ASN   B ND2    1 
ATOM   2516 N N      . GLY   E 1 200 ? 244.005 213.825 203.873 1.00 78.87  ? 212 GLY   B N      1 
ATOM   2517 C CA     . GLY   E 1 200 ? 243.187 214.872 203.283 1.00 72.19  ? 212 GLY   B CA     1 
ATOM   2518 C C      . GLY   E 1 200 ? 242.797 215.932 204.293 1.00 70.68  ? 212 GLY   B C      1 
ATOM   2519 O O      . GLY   E 1 200 ? 242.693 217.115 203.960 1.00 71.34  ? 212 GLY   B O      1 
ATOM   2520 N N      . ARG   E 1 201 ? 242.571 215.521 205.541 1.00 73.20  ? 213 ARG   B N      1 
ATOM   2521 C CA     . ARG   E 1 201 ? 242.308 216.487 206.600 1.00 76.43  ? 213 ARG   B CA     1 
ATOM   2522 C C      . ARG   E 1 201 ? 243.504 217.404 206.815 1.00 69.52  ? 213 ARG   B C      1 
ATOM   2523 O O      . ARG   E 1 201 ? 243.346 218.621 206.967 1.00 68.13  ? 213 ARG   B O      1 
ATOM   2524 C CB     . ARG   E 1 201 ? 241.957 215.752 207.893 1.00 91.29  ? 213 ARG   B CB     1 
ATOM   2525 C CG     . ARG   E 1 201 ? 240.672 214.946 207.819 1.00 97.77  ? 213 ARG   B CG     1 
ATOM   2526 C CD     . ARG   E 1 201 ? 240.363 214.281 209.147 1.00 103.79 ? 213 ARG   B CD     1 
ATOM   2527 N NE     . ARG   E 1 201 ? 239.172 213.445 209.074 1.00 116.20 ? 213 ARG   B NE     1 
ATOM   2528 C CZ     . ARG   E 1 201 ? 238.729 212.685 210.067 1.00 129.13 ? 213 ARG   B CZ     1 
ATOM   2529 N NH1    . ARG   E 1 201 ? 239.357 212.633 211.230 1.00 134.58 ? 213 ARG   B NH1    1 
ATOM   2530 N NH2    . ARG   E 1 201 ? 237.628 211.962 209.888 1.00 134.03 ? 213 ARG   B NH2    1 
ATOM   2531 N N      . ARG   E 1 202 ? 244.712 216.837 206.835 1.00 71.19  ? 214 ARG   B N      1 
ATOM   2532 C CA     . ARG   E 1 202 ? 245.912 217.652 206.992 1.00 68.48  ? 214 ARG   B CA     1 
ATOM   2533 C C      . ARG   E 1 202 ? 246.095 218.598 205.814 1.00 65.07  ? 214 ARG   B C      1 
ATOM   2534 O O      . ARG   E 1 202 ? 246.469 219.762 205.992 1.00 62.15  ? 214 ARG   B O      1 
ATOM   2535 C CB     . ARG   E 1 202 ? 247.138 216.754 207.146 1.00 76.84  ? 214 ARG   B CB     1 
ATOM   2536 C CG     . ARG   E 1 202 ? 246.838 215.389 207.734 1.00 84.04  ? 214 ARG   B CG     1 
ATOM   2537 C CD     . ARG   E 1 202 ? 248.117 214.609 207.966 1.00 87.85  ? 214 ARG   B CD     1 
ATOM   2538 N NE     . ARG   E 1 202 ? 249.133 215.424 208.620 1.00 89.94  ? 214 ARG   B NE     1 
ATOM   2539 C CZ     . ARG   E 1 202 ? 248.994 215.982 209.815 1.00 94.12  ? 214 ARG   B CZ     1 
ATOM   2540 N NH1    . ARG   E 1 202 ? 247.888 215.831 210.523 1.00 94.94  ? 214 ARG   B NH1    1 
ATOM   2541 N NH2    . ARG   E 1 202 ? 249.990 216.709 210.311 1.00 99.27  ? 214 ARG   B NH2    1 
ATOM   2542 N N      . THR   E 1 203 ? 245.856 218.109 204.597 1.00 66.28  ? 215 THR   B N      1 
ATOM   2543 C CA     . THR   E 1 203 ? 245.976 218.966 203.424 1.00 59.54  ? 215 THR   B CA     1 
ATOM   2544 C C      . THR   E 1 203 ? 244.949 220.090 203.459 1.00 57.22  ? 215 THR   B C      1 
ATOM   2545 O O      . THR   E 1 203 ? 245.237 221.218 203.044 1.00 56.26  ? 215 THR   B O      1 
ATOM   2546 C CB     . THR   E 1 203 ? 245.824 218.138 202.149 1.00 63.02  ? 215 THR   B CB     1 
ATOM   2547 O OG1    . THR   E 1 203 ? 244.521 217.544 202.117 1.00 71.91  ? 215 THR   B OG1    1 
ATOM   2548 C CG2    . THR   E 1 203 ? 246.874 217.042 202.101 1.00 58.91  ? 215 THR   B CG2    1 
ATOM   2549 N N      . ARG   E 1 204 ? 243.738 219.800 203.937 1.00 60.84  ? 216 ARG   B N      1 
ATOM   2550 C CA     . ARG   E 1 204 ? 242.703 220.826 203.980 1.00 60.45  ? 216 ARG   B CA     1 
ATOM   2551 C C      . ARG   E 1 204 ? 243.087 221.955 204.928 1.00 58.42  ? 216 ARG   B C      1 
ATOM   2552 O O      . ARG   E 1 204 ? 242.918 223.133 204.596 1.00 61.06  ? 216 ARG   B O      1 
ATOM   2553 C CB     . ARG   E 1 204 ? 241.365 220.204 204.385 1.00 62.71  ? 216 ARG   B CB     1 
ATOM   2554 C CG     . ARG   E 1 204 ? 240.210 221.190 204.503 1.00 61.17  ? 216 ARG   B CG     1 
ATOM   2555 C CD     . ARG   E 1 204 ? 240.373 222.363 203.555 1.00 60.86  ? 216 ARG   B CD     1 
ATOM   2556 N NE     . ARG   E 1 204 ? 239.159 223.160 203.443 1.00 65.18  ? 216 ARG   B NE     1 
ATOM   2557 C CZ     . ARG   E 1 204 ? 238.291 223.071 202.445 1.00 71.84  ? 216 ARG   B CZ     1 
ATOM   2558 N NH1    . ARG   E 1 204 ? 238.465 222.213 201.454 1.00 73.65  ? 216 ARG   B NH1    1 
ATOM   2559 N NH2    . ARG   E 1 204 ? 237.225 223.866 202.441 1.00 68.79  ? 216 ARG   B NH2    1 
ATOM   2560 N N      . ILE   E 1 205 ? 243.617 221.623 206.105 1.00 55.97  ? 217 ILE   B N      1 
ATOM   2561 C CA     . ILE   E 1 205 ? 244.025 222.671 207.035 1.00 55.54  ? 217 ILE   B CA     1 
ATOM   2562 C C      . ILE   E 1 205 ? 245.165 223.490 206.448 1.00 57.01  ? 217 ILE   B C      1 
ATOM   2563 O O      . ILE   E 1 205 ? 245.204 224.717 206.595 1.00 61.69  ? 217 ILE   B O      1 
ATOM   2564 C CB     . ILE   E 1 205 ? 244.399 222.075 208.403 1.00 62.02  ? 217 ILE   B CB     1 
ATOM   2565 C CG1    . ILE   E 1 205 ? 244.979 223.166 209.303 1.00 57.57  ? 217 ILE   B CG1    1 
ATOM   2566 C CG2    . ILE   E 1 205 ? 245.376 220.928 208.243 1.00 64.92  ? 217 ILE   B CG2    1 
ATOM   2567 C CD1    . ILE   E 1 205 ? 244.128 224.410 209.365 1.00 50.81  ? 217 ILE   B CD1    1 
ATOM   2568 N N      . ALA   E 1 206 ? 246.110 222.832 205.775 1.00 53.92  ? 218 ALA   B N      1 
ATOM   2569 C CA     . ALA   E 1 206 ? 247.175 223.568 205.104 1.00 53.27  ? 218 ALA   B CA     1 
ATOM   2570 C C      . ALA   E 1 206 ? 246.609 224.469 204.013 1.00 53.55  ? 218 ALA   B C      1 
ATOM   2571 O O      . ALA   E 1 206 ? 247.038 225.618 203.861 1.00 53.64  ? 218 ALA   B O      1 
ATOM   2572 C CB     . ALA   E 1 206 ? 248.201 222.596 204.525 1.00 54.11  ? 218 ALA   B CB     1 
ATOM   2573 N N      . TYR   E 1 207 ? 245.638 223.963 203.251 1.00 54.48  ? 219 TYR   B N      1 
ATOM   2574 C CA     . TYR   E 1 207 ? 245.006 224.769 202.213 1.00 52.03  ? 219 TYR   B CA     1 
ATOM   2575 C C      . TYR   E 1 207 ? 244.298 225.977 202.814 1.00 51.39  ? 219 TYR   B C      1 
ATOM   2576 O O      . TYR   E 1 207 ? 244.357 227.080 202.259 1.00 49.85  ? 219 TYR   B O      1 
ATOM   2577 C CB     . TYR   E 1 207 ? 244.035 223.894 201.414 1.00 53.58  ? 219 TYR   B CB     1 
ATOM   2578 C CG     . TYR   E 1 207 ? 243.244 224.592 200.328 1.00 55.12  ? 219 TYR   B CG     1 
ATOM   2579 C CD1    . TYR   E 1 207 ? 242.204 225.457 200.636 1.00 57.99  ? 219 TYR   B CD1    1 
ATOM   2580 C CD2    . TYR   E 1 207 ? 243.527 224.365 198.991 1.00 56.68  ? 219 TYR   B CD2    1 
ATOM   2581 C CE1    . TYR   E 1 207 ? 241.480 226.084 199.644 1.00 57.62  ? 219 TYR   B CE1    1 
ATOM   2582 C CE2    . TYR   E 1 207 ? 242.810 224.988 197.994 1.00 57.79  ? 219 TYR   B CE2    1 
ATOM   2583 C CZ     . TYR   E 1 207 ? 241.788 225.846 198.325 1.00 58.88  ? 219 TYR   B CZ     1 
ATOM   2584 O OH     . TYR   E 1 207 ? 241.069 226.469 197.334 1.00 64.04  ? 219 TYR   B OH     1 
ATOM   2585 N N      . GLU   E 1 208 ? 243.621 225.787 203.948 1.00 51.11  ? 220 GLU   B N      1 
ATOM   2586 C CA     . GLU   E 1 208 ? 242.914 226.891 204.588 1.00 49.11  ? 220 GLU   B CA     1 
ATOM   2587 C C      . GLU   E 1 208 ? 243.883 227.971 205.054 1.00 48.98  ? 220 GLU   B C      1 
ATOM   2588 O O      . GLU   E 1 208 ? 243.636 229.168 204.868 1.00 49.30  ? 220 GLU   B O      1 
ATOM   2589 C CB     . GLU   E 1 208 ? 242.093 226.370 205.768 1.00 56.73  ? 220 GLU   B CB     1 
ATOM   2590 C CG     . GLU   E 1 208 ? 241.168 225.212 205.434 1.00 62.50  ? 220 GLU   B CG     1 
ATOM   2591 C CD     . GLU   E 1 208 ? 239.891 225.656 204.758 1.00 68.20  ? 220 GLU   B CD     1 
ATOM   2592 O OE1    . GLU   E 1 208 ? 238.819 225.106 205.087 1.00 62.32  ? 220 GLU   B OE1    1 
ATOM   2593 O OE2    . GLU   E 1 208 ? 239.959 226.547 203.889 1.00 71.68  ? 220 GLU   B OE2    1 
ATOM   2594 N N      . ARG   E 1 209 ? 244.992 227.565 205.674 1.00 50.14  ? 221 ARG   B N      1 
ATOM   2595 C CA     . ARG   E 1 209 ? 245.905 228.531 206.277 1.00 48.42  ? 221 ARG   B CA     1 
ATOM   2596 C C      . ARG   E 1 209 ? 246.544 229.427 205.223 1.00 45.85  ? 221 ARG   B C      1 
ATOM   2597 O O      . ARG   E 1 209 ? 246.635 230.647 205.404 1.00 43.61  ? 221 ARG   B O      1 
ATOM   2598 C CB     . ARG   E 1 209 ? 246.976 227.802 207.088 1.00 51.93  ? 221 ARG   B CB     1 
ATOM   2599 C CG     . ARG   E 1 209 ? 248.023 228.717 207.691 1.00 55.82  ? 221 ARG   B CG     1 
ATOM   2600 C CD     . ARG   E 1 209 ? 248.482 228.210 209.044 1.00 60.34  ? 221 ARG   B CD     1 
ATOM   2601 N NE     . ARG   E 1 209 ? 249.841 227.687 209.000 1.00 69.81  ? 221 ARG   B NE     1 
ATOM   2602 C CZ     . ARG   E 1 209 ? 250.142 226.399 208.911 1.00 84.61  ? 221 ARG   B CZ     1 
ATOM   2603 N NH1    . ARG   E 1 209 ? 249.200 225.473 208.851 1.00 84.53  ? 221 ARG   B NH1    1 
ATOM   2604 N NH2    . ARG   E 1 209 ? 251.420 226.032 208.882 1.00 92.48  ? 221 ARG   B NH2    1 
ATOM   2605 N N      . MET   E 1 210 ? 247.000 228.840 204.117 1.00 46.96  ? 222 MET   B N      1 
ATOM   2606 C CA     . MET   E 1 210 ? 247.655 229.635 203.085 1.00 46.80  ? 222 MET   B CA     1 
ATOM   2607 C C      . MET   E 1 210 ? 246.653 230.458 202.285 1.00 46.07  ? 222 MET   B C      1 
ATOM   2608 O O      . MET   E 1 210 ? 247.027 231.472 201.685 1.00 45.98  ? 222 MET   B O      1 
ATOM   2609 C CB     . MET   E 1 210 ? 248.491 228.725 202.184 1.00 44.66  ? 222 MET   B CB     1 
ATOM   2610 C CG     . MET   E 1 210 ? 247.742 228.050 201.063 1.00 49.21  ? 222 MET   B CG     1 
ATOM   2611 S SD     . MET   E 1 210 ? 248.858 227.052 200.058 1.00 53.86  ? 222 MET   B SD     1 
ATOM   2612 C CE     . MET   E 1 210 ? 250.096 226.620 201.272 1.00 45.27  ? 222 MET   B CE     1 
ATOM   2613 N N      . CYS   E 1 211 ? 245.384 230.050 202.266 1.00 48.75  ? 223 CYS   B N      1 
ATOM   2614 C CA     . CYS   E 1 211 ? 244.353 230.905 201.688 1.00 46.80  ? 223 CYS   B CA     1 
ATOM   2615 C C      . CYS   E 1 211 ? 244.124 232.147 202.542 1.00 44.96  ? 223 CYS   B C      1 
ATOM   2616 O O      . CYS   E 1 211 ? 243.942 233.247 202.010 1.00 42.52  ? 223 CYS   B O      1 
ATOM   2617 C CB     . CYS   E 1 211 ? 243.053 230.121 201.511 1.00 46.31  ? 223 CYS   B CB     1 
ATOM   2618 S SG     . CYS   E 1 211 ? 242.999 229.075 200.041 1.00 63.40  ? 223 CYS   B SG     1 
ATOM   2619 N N      . ASN   E 1 212 ? 244.137 231.994 203.868 1.00 48.19  ? 224 ASN   B N      1 
ATOM   2620 C CA     . ASN   E 1 212 ? 243.942 233.143 204.746 1.00 45.85  ? 224 ASN   B CA     1 
ATOM   2621 C C      . ASN   E 1 212 ? 245.088 234.138 204.625 1.00 44.75  ? 224 ASN   B C      1 
ATOM   2622 O O      . ASN   E 1 212 ? 244.866 235.352 204.570 1.00 46.40  ? 224 ASN   B O      1 
ATOM   2623 C CB     . ASN   E 1 212 ? 243.799 232.682 206.195 1.00 47.23  ? 224 ASN   B CB     1 
ATOM   2624 C CG     . ASN   E 1 212 ? 242.360 232.455 206.596 1.00 56.42  ? 224 ASN   B CG     1 
ATOM   2625 O OD1    . ASN   E 1 212 ? 241.732 231.477 206.189 1.00 61.80  ? 224 ASN   B OD1    1 
ATOM   2626 N ND2    . ASN   E 1 212 ? 241.825 233.364 207.400 1.00 56.67  ? 224 ASN   B ND2    1 
ATOM   2627 N N      . ILE   E 1 213 ? 246.326 233.644 204.602 1.00 45.29  ? 225 ILE   B N      1 
ATOM   2628 C CA     . ILE   E 1 213 ? 247.470 234.540 204.479 1.00 46.06  ? 225 ILE   B CA     1 
ATOM   2629 C C      . ILE   E 1 213 ? 247.517 235.179 203.097 1.00 43.37  ? 225 ILE   B C      1 
ATOM   2630 O O      . ILE   E 1 213 ? 247.959 236.326 202.952 1.00 42.86  ? 225 ILE   B O      1 
ATOM   2631 C CB     . ILE   E 1 213 ? 248.766 233.784 204.831 1.00 46.12  ? 225 ILE   B CB     1 
ATOM   2632 C CG1    . ILE   E 1 213 ? 249.216 232.900 203.674 1.00 45.90  ? 225 ILE   B CG1    1 
ATOM   2633 C CG2    . ILE   E 1 213 ? 248.581 232.954 206.083 1.00 48.40  ? 225 ILE   B CG2    1 
ATOM   2634 C CD1    . ILE   E 1 213 ? 250.308 231.916 204.056 1.00 44.81  ? 225 ILE   B CD1    1 
ATOM   2635 N N      . LEU   E 1 214 ? 247.073 234.461 202.063 1.00 44.80  ? 226 LEU   B N      1 
ATOM   2636 C CA     . LEU   E 1 214 ? 246.918 235.082 200.752 1.00 42.90  ? 226 LEU   B CA     1 
ATOM   2637 C C      . LEU   E 1 214 ? 245.842 236.158 200.781 1.00 41.66  ? 226 LEU   B C      1 
ATOM   2638 O O      . LEU   E 1 214 ? 245.987 237.211 200.151 1.00 38.84  ? 226 LEU   B O      1 
ATOM   2639 C CB     . LEU   E 1 214 ? 246.587 234.026 199.701 1.00 40.16  ? 226 LEU   B CB     1 
ATOM   2640 C CG     . LEU   E 1 214 ? 246.084 234.571 198.363 1.00 39.38  ? 226 LEU   B CG     1 
ATOM   2641 C CD1    . LEU   E 1 214 ? 247.104 235.504 197.734 1.00 41.45  ? 226 LEU   B CD1    1 
ATOM   2642 C CD2    . LEU   E 1 214 ? 245.750 233.429 197.424 1.00 40.68  ? 226 LEU   B CD2    1 
ATOM   2643 N N      . LYS   E 1 215 ? 244.746 235.899 201.496 1.00 45.94  ? 227 LYS   B N      1 
ATOM   2644 C CA     . LYS   E 1 215 ? 243.664 236.874 201.590 1.00 45.45  ? 227 LYS   B CA     1 
ATOM   2645 C C      . LYS   E 1 215 ? 244.124 238.146 202.290 1.00 45.23  ? 227 LYS   B C      1 
ATOM   2646 O O      . LYS   E 1 215 ? 243.775 239.255 201.870 1.00 47.39  ? 227 LYS   B O      1 
ATOM   2647 C CB     . LYS   E 1 215 ? 242.474 236.252 202.318 1.00 48.16  ? 227 LYS   B CB     1 
ATOM   2648 C CG     . LYS   E 1 215 ? 241.394 237.232 202.722 1.00 47.14  ? 227 LYS   B CG     1 
ATOM   2649 C CD     . LYS   E 1 215 ? 240.251 236.516 203.418 1.00 48.48  ? 227 LYS   B CD     1 
ATOM   2650 C CE     . LYS   E 1 215 ? 239.985 237.110 204.786 1.00 50.47  ? 227 LYS   B CE     1 
ATOM   2651 N NZ     . LYS   E 1 215 ? 240.039 238.595 204.767 1.00 56.02  ? 227 LYS   B NZ     1 
ATOM   2652 N N      . GLY   E 1 216 ? 244.904 238.007 203.362 1.00 45.07  ? 228 GLY   B N      1 
ATOM   2653 C CA     . GLY   E 1 216 ? 245.442 239.172 204.038 1.00 42.63  ? 228 GLY   B CA     1 
ATOM   2654 C C      . GLY   E 1 216 ? 246.443 239.944 203.210 1.00 42.33  ? 228 GLY   B C      1 
ATOM   2655 O O      . GLY   E 1 216 ? 246.759 241.090 203.545 1.00 42.79  ? 228 GLY   B O      1 
ATOM   2656 N N      . LYS   E 1 217 ? 246.952 239.338 202.137 1.00 43.06  ? 229 LYS   B N      1 
ATOM   2657 C CA     . LYS   E 1 217 ? 247.900 240.024 201.270 1.00 40.41  ? 229 LYS   B CA     1 
ATOM   2658 C C      . LYS   E 1 217 ? 247.206 241.056 200.390 1.00 41.80  ? 229 LYS   B C      1 
ATOM   2659 O O      . LYS   E 1 217 ? 247.836 242.029 199.964 1.00 45.00  ? 229 LYS   B O      1 
ATOM   2660 C CB     . LYS   E 1 217 ? 248.644 238.997 200.417 1.00 38.83  ? 229 LYS   B CB     1 
ATOM   2661 C CG     . LYS   E 1 217 ? 250.034 239.411 199.987 1.00 40.63  ? 229 LYS   B CG     1 
ATOM   2662 C CD     . LYS   E 1 217 ? 250.894 238.189 199.709 1.00 40.78  ? 229 LYS   B CD     1 
ATOM   2663 C CE     . LYS   E 1 217 ? 251.274 237.467 200.990 1.00 37.21  ? 229 LYS   B CE     1 
ATOM   2664 N NZ     . LYS   E 1 217 ? 251.950 238.365 201.959 1.00 37.22  ? 229 LYS   B NZ     1 
ATOM   2665 N N      . PHE   E 1 218 ? 245.921 240.862 200.111 1.00 43.31  ? 230 PHE   B N      1 
ATOM   2666 C CA     . PHE   E 1 218 ? 245.167 241.759 199.253 1.00 41.82  ? 230 PHE   B CA     1 
ATOM   2667 C C      . PHE   E 1 218 ? 244.676 242.972 200.042 1.00 45.64  ? 230 PHE   B C      1 
ATOM   2668 O O      . PHE   E 1 218 ? 244.647 242.980 201.274 1.00 51.75  ? 230 PHE   B O      1 
ATOM   2669 C CB     . PHE   E 1 218 ? 243.989 241.024 198.622 1.00 40.39  ? 230 PHE   B CB     1 
ATOM   2670 C CG     . PHE   E 1 218 ? 244.349 240.254 197.388 1.00 39.62  ? 230 PHE   B CG     1 
ATOM   2671 C CD1    . PHE   E 1 218 ? 244.957 240.881 196.317 1.00 41.10  ? 230 PHE   B CD1    1 
ATOM   2672 C CD2    . PHE   E 1 218 ? 244.065 238.904 197.294 1.00 40.61  ? 230 PHE   B CD2    1 
ATOM   2673 C CE1    . PHE   E 1 218 ? 245.285 240.173 195.181 1.00 42.65  ? 230 PHE   B CE1    1 
ATOM   2674 C CE2    . PHE   E 1 218 ? 244.390 238.193 196.160 1.00 41.83  ? 230 PHE   B CE2    1 
ATOM   2675 C CZ     . PHE   E 1 218 ? 245.000 238.828 195.101 1.00 42.46  ? 230 PHE   B CZ     1 
ATOM   2676 N N      . GLN   E 1 219 ? 244.277 244.009 199.310 1.00 42.07  ? 231 GLN   B N      1 
ATOM   2677 C CA     . GLN   E 1 219 ? 243.840 245.259 199.918 1.00 43.11  ? 231 GLN   B CA     1 
ATOM   2678 C C      . GLN   E 1 219 ? 242.390 245.591 199.606 1.00 45.87  ? 231 GLN   B C      1 
ATOM   2679 O O      . GLN   E 1 219 ? 241.638 245.962 200.514 1.00 48.63  ? 231 GLN   B O      1 
ATOM   2680 C CB     . GLN   E 1 219 ? 244.756 246.406 199.465 1.00 42.55  ? 231 GLN   B CB     1 
ATOM   2681 C CG     . GLN   E 1 219 ? 245.968 246.605 200.357 1.00 44.66  ? 231 GLN   B CG     1 
ATOM   2682 C CD     . GLN   E 1 219 ? 246.851 247.744 199.899 1.00 51.63  ? 231 GLN   B CD     1 
ATOM   2683 O OE1    . GLN   E 1 219 ? 247.629 248.293 200.677 1.00 53.94  ? 231 GLN   B OE1    1 
ATOM   2684 N NE2    . GLN   E 1 219 ? 246.741 248.103 198.627 1.00 53.83  ? 231 GLN   B NE2    1 
ATOM   2685 N N      . THR   E 1 220 ? 241.972 245.475 198.350 1.00 44.35  ? 232 THR   B N      1 
ATOM   2686 C CA     . THR   E 1 220 ? 240.587 245.756 197.999 1.00 41.06  ? 232 THR   B CA     1 
ATOM   2687 C C      . THR   E 1 220 ? 239.659 244.695 198.578 1.00 42.27  ? 232 THR   B C      1 
ATOM   2688 O O      . THR   E 1 220 ? 240.013 243.517 198.668 1.00 43.52  ? 232 THR   B O      1 
ATOM   2689 C CB     . THR   E 1 220 ? 240.418 245.823 196.482 1.00 43.09  ? 232 THR   B CB     1 
ATOM   2690 O OG1    . THR   E 1 220 ? 240.645 244.526 195.918 1.00 49.23  ? 232 THR   B OG1    1 
ATOM   2691 C CG2    . THR   E 1 220 ? 241.401 246.811 195.882 1.00 40.76  ? 232 THR   B CG2    1 
ATOM   2692 N N      . ALA   E 1 221 ? 238.459 245.125 198.970 1.00 41.40  ? 233 ALA   B N      1 
ATOM   2693 C CA     . ALA   E 1 221 ? 237.490 244.198 199.545 1.00 38.04  ? 233 ALA   B CA     1 
ATOM   2694 C C      . ALA   E 1 221 ? 237.033 243.167 198.520 1.00 41.22  ? 233 ALA   B C      1 
ATOM   2695 O O      . ALA   E 1 221 ? 236.767 242.012 198.869 1.00 45.01  ? 233 ALA   B O      1 
ATOM   2696 C CB     . ALA   E 1 221 ? 236.295 244.970 200.102 1.00 32.35  ? 233 ALA   B CB     1 
ATOM   2697 N N      . ALA   E 1 222 ? 236.942 243.564 197.250 1.00 39.23  ? 234 ALA   B N      1 
ATOM   2698 C CA     . ALA   E 1 222 ? 236.492 242.637 196.219 1.00 41.86  ? 234 ALA   B CA     1 
ATOM   2699 C C      . ALA   E 1 222 ? 237.440 241.453 196.089 1.00 43.18  ? 234 ALA   B C      1 
ATOM   2700 O O      . ALA   E 1 222 ? 236.998 240.305 195.965 1.00 43.51  ? 234 ALA   B O      1 
ATOM   2701 C CB     . ALA   E 1 222 ? 236.356 243.369 194.885 1.00 46.66  ? 234 ALA   B CB     1 
ATOM   2702 N N      . GLN   E 1 223 ? 238.747 241.711 196.121 1.00 45.17  ? 235 GLN   B N      1 
ATOM   2703 C CA     . GLN   E 1 223 ? 239.719 240.629 196.006 1.00 42.90  ? 235 GLN   B CA     1 
ATOM   2704 C C      . GLN   E 1 223 ? 239.632 239.675 197.193 1.00 45.42  ? 235 GLN   B C      1 
ATOM   2705 O O      . GLN   E 1 223 ? 239.706 238.453 197.023 1.00 47.06  ? 235 GLN   B O      1 
ATOM   2706 C CB     . GLN   E 1 223 ? 241.127 241.210 195.879 1.00 40.01  ? 235 GLN   B CB     1 
ATOM   2707 C CG     . GLN   E 1 223 ? 241.503 241.609 194.462 1.00 39.52  ? 235 GLN   B CG     1 
ATOM   2708 C CD     . GLN   E 1 223 ? 242.607 242.648 194.414 1.00 38.43  ? 235 GLN   B CD     1 
ATOM   2709 O OE1    . GLN   E 1 223 ? 242.693 243.522 195.272 1.00 37.56  ? 235 GLN   B OE1    1 
ATOM   2710 N NE2    . GLN   E 1 223 ? 243.452 242.561 193.396 1.00 39.77  ? 235 GLN   B NE2    1 
ATOM   2711 N N      . ARG   E 1 224 ? 239.476 240.214 198.406 1.00 44.11  ? 236 ARG   B N      1 
ATOM   2712 C CA     . ARG   E 1 224 ? 239.402 239.360 199.588 1.00 43.66  ? 236 ARG   B CA     1 
ATOM   2713 C C      . ARG   E 1 224 ? 238.167 238.471 199.556 1.00 44.58  ? 236 ARG   B C      1 
ATOM   2714 O O      . ARG   E 1 224 ? 238.228 237.295 199.931 1.00 48.24  ? 236 ARG   B O      1 
ATOM   2715 C CB     . ARG   E 1 224 ? 239.416 240.211 200.857 1.00 45.25  ? 236 ARG   B CB     1 
ATOM   2716 C CG     . ARG   E 1 224 ? 240.601 241.148 200.952 1.00 44.20  ? 236 ARG   B CG     1 
ATOM   2717 C CD     . ARG   E 1 224 ? 241.206 241.097 202.340 1.00 45.76  ? 236 ARG   B CD     1 
ATOM   2718 N NE     . ARG   E 1 224 ? 240.738 242.184 203.189 1.00 47.66  ? 236 ARG   B NE     1 
ATOM   2719 C CZ     . ARG   E 1 224 ? 241.060 243.458 203.023 1.00 53.78  ? 236 ARG   B CZ     1 
ATOM   2720 N NH1    . ARG   E 1 224 ? 241.874 243.845 202.056 1.00 56.47  ? 236 ARG   B NH1    1 
ATOM   2721 N NH2    . ARG   E 1 224 ? 240.561 244.367 203.855 1.00 52.13  ? 236 ARG   B NH2    1 
ATOM   2722 N N      . THR   E 1 225 ? 237.031 239.018 199.125 1.00 44.22  ? 237 THR   B N      1 
ATOM   2723 C CA     . THR   E 1 225 ? 235.817 238.217 199.038 1.00 46.58  ? 237 THR   B CA     1 
ATOM   2724 C C      . THR   E 1 225 ? 235.968 237.107 198.007 1.00 47.00  ? 237 THR   B C      1 
ATOM   2725 O O      . THR   E 1 225 ? 235.449 236.000 198.191 1.00 47.29  ? 237 THR   B O      1 
ATOM   2726 C CB     . THR   E 1 225 ? 234.627 239.113 198.702 1.00 47.61  ? 237 THR   B CB     1 
ATOM   2727 O OG1    . THR   E 1 225 ? 234.855 239.750 197.440 1.00 53.95  ? 237 THR   B OG1    1 
ATOM   2728 C CG2    . THR   E 1 225 ? 234.451 240.183 199.768 1.00 45.11  ? 237 THR   B CG2    1 
ATOM   2729 N N      . MET   E 1 226 ? 236.673 237.387 196.910 1.00 45.15  ? 238 MET   B N      1 
ATOM   2730 C CA     . MET   E 1 226 ? 236.902 236.365 195.895 1.00 45.37  ? 238 MET   B CA     1 
ATOM   2731 C C      . MET   E 1 226 ? 237.755 235.221 196.439 1.00 45.88  ? 238 MET   B C      1 
ATOM   2732 O O      . MET   E 1 226 ? 237.494 234.051 196.136 1.00 44.78  ? 238 MET   B O      1 
ATOM   2733 C CB     . MET   E 1 226 ? 237.552 237.004 194.668 1.00 46.66  ? 238 MET   B CB     1 
ATOM   2734 C CG     . MET   E 1 226 ? 237.929 236.042 193.565 1.00 51.15  ? 238 MET   B CG     1 
ATOM   2735 S SD     . MET   E 1 226 ? 237.396 236.604 191.943 1.00 65.89  ? 238 MET   B SD     1 
ATOM   2736 C CE     . MET   E 1 226 ? 238.173 235.350 190.932 1.00 56.13  ? 238 MET   B CE     1 
ATOM   2737 N N      . VAL   E 1 227 ? 238.791 235.535 197.226 1.00 46.28  ? 239 VAL   B N      1 
ATOM   2738 C CA     . VAL   E 1 227 ? 239.606 234.476 197.819 1.00 49.49  ? 239 VAL   B CA     1 
ATOM   2739 C C      . VAL   E 1 227 ? 238.811 233.702 198.861 1.00 49.56  ? 239 VAL   B C      1 
ATOM   2740 O O      . VAL   E 1 227 ? 238.992 232.488 199.016 1.00 48.63  ? 239 VAL   B O      1 
ATOM   2741 C CB     . VAL   E 1 227 ? 240.902 235.052 198.422 1.00 49.11  ? 239 VAL   B CB     1 
ATOM   2742 C CG1    . VAL   E 1 227 ? 240.661 235.528 199.837 1.00 43.74  ? 239 VAL   B CG1    1 
ATOM   2743 C CG2    . VAL   E 1 227 ? 242.022 234.010 198.396 1.00 51.76  ? 239 VAL   B CG2    1 
ATOM   2744 N N      . ASP   E 1 228 ? 237.932 234.382 199.596 1.00 51.54  ? 240 ASP   B N      1 
ATOM   2745 C CA     . ASP   E 1 228 ? 237.151 233.711 200.627 1.00 51.39  ? 240 ASP   B CA     1 
ATOM   2746 C C      . ASP   E 1 228 ? 236.244 232.647 200.021 1.00 51.61  ? 240 ASP   B C      1 
ATOM   2747 O O      . ASP   E 1 228 ? 236.046 231.579 200.610 1.00 55.91  ? 240 ASP   B O      1 
ATOM   2748 C CB     . ASP   E 1 228 ? 236.338 234.742 201.409 1.00 51.42  ? 240 ASP   B CB     1 
ATOM   2749 C CG     . ASP   E 1 228 ? 236.443 234.553 202.906 1.00 60.06  ? 240 ASP   B CG     1 
ATOM   2750 O OD1    . ASP   E 1 228 ? 237.082 233.572 203.342 1.00 68.50  ? 240 ASP   B OD1    1 
ATOM   2751 O OD2    . ASP   E 1 228 ? 235.902 235.397 203.650 1.00 62.30  ? 240 ASP   B OD2    1 
ATOM   2752 N N      . GLN   E 1 229 ? 235.675 232.927 198.847 1.00 51.75  ? 241 GLN   B N      1 
ATOM   2753 C CA     . GLN   E 1 229 ? 234.840 231.935 198.178 1.00 51.42  ? 241 GLN   B CA     1 
ATOM   2754 C C      . GLN   E 1 229 ? 235.643 230.698 197.800 1.00 52.04  ? 241 GLN   B C      1 
ATOM   2755 O O      . GLN   E 1 229 ? 235.184 229.567 197.997 1.00 55.47  ? 241 GLN   B O      1 
ATOM   2756 C CB     . GLN   E 1 229 ? 234.192 232.545 196.938 1.00 47.25  ? 241 GLN   B CB     1 
ATOM   2757 C CG     . GLN   E 1 229 ? 233.542 233.889 197.172 1.00 51.38  ? 241 GLN   B CG     1 
ATOM   2758 C CD     . GLN   E 1 229 ? 232.862 234.414 195.931 1.00 58.00  ? 241 GLN   B CD     1 
ATOM   2759 O OE1    . GLN   E 1 229 ? 232.879 233.768 194.884 1.00 54.94  ? 241 GLN   B OE1    1 
ATOM   2760 N NE2    . GLN   E 1 229 ? 232.267 235.596 196.034 1.00 67.00  ? 241 GLN   B NE2    1 
ATOM   2761 N N      . VAL   E 1 230 ? 236.845 230.891 197.254 1.00 50.34  ? 242 VAL   B N      1 
ATOM   2762 C CA     . VAL   E 1 230 ? 237.646 229.757 196.802 1.00 51.59  ? 242 VAL   B CA     1 
ATOM   2763 C C      . VAL   E 1 230 ? 238.001 228.856 197.976 1.00 55.43  ? 242 VAL   B C      1 
ATOM   2764 O O      . VAL   E 1 230 ? 238.065 227.629 197.842 1.00 57.84  ? 242 VAL   B O      1 
ATOM   2765 C CB     . VAL   E 1 230 ? 238.905 230.252 196.066 1.00 51.27  ? 242 VAL   B CB     1 
ATOM   2766 C CG1    . VAL   E 1 230 ? 239.850 229.096 195.805 1.00 54.14  ? 242 VAL   B CG1    1 
ATOM   2767 C CG2    . VAL   E 1 230 ? 238.524 230.937 194.766 1.00 52.77  ? 242 VAL   B CG2    1 
ATOM   2768 N N      . ARG   E 1 231 ? 238.237 229.451 199.145 1.00 55.18  ? 243 ARG   B N      1 
ATOM   2769 C CA     . ARG   E 1 231 ? 238.600 228.668 200.319 1.00 54.00  ? 243 ARG   B CA     1 
ATOM   2770 C C      . ARG   E 1 231 ? 237.473 227.730 200.739 1.00 59.17  ? 243 ARG   B C      1 
ATOM   2771 O O      . ARG   E 1 231 ? 237.726 226.595 201.159 1.00 65.90  ? 243 ARG   B O      1 
ATOM   2772 C CB     . ARG   E 1 231 ? 238.983 229.602 201.464 1.00 53.68  ? 243 ARG   B CB     1 
ATOM   2773 C CG     . ARG   E 1 231 ? 239.013 228.940 202.816 1.00 57.53  ? 243 ARG   B CG     1 
ATOM   2774 C CD     . ARG   E 1 231 ? 239.634 229.855 203.844 1.00 56.05  ? 243 ARG   B CD     1 
ATOM   2775 N NE     . ARG   E 1 231 ? 238.836 231.054 204.052 1.00 54.48  ? 243 ARG   B NE     1 
ATOM   2776 C CZ     . ARG   E 1 231 ? 238.598 231.594 205.238 1.00 59.96  ? 243 ARG   B CZ     1 
ATOM   2777 N NH1    . ARG   E 1 231 ? 239.088 231.066 206.347 1.00 57.75  ? 243 ARG   B NH1    1 
ATOM   2778 N NH2    . ARG   E 1 231 ? 237.851 232.691 205.313 1.00 64.96  ? 243 ARG   B NH2    1 
ATOM   2779 N N      . GLU   E 1 232 ? 236.223 228.185 200.636 1.00 57.67  ? 244 GLU   B N      1 
ATOM   2780 C CA     . GLU   E 1 232 ? 235.086 227.377 201.060 1.00 58.26  ? 244 GLU   B CA     1 
ATOM   2781 C C      . GLU   E 1 232 ? 234.892 226.114 200.229 1.00 59.52  ? 244 GLU   B C      1 
ATOM   2782 O O      . GLU   E 1 232 ? 234.235 225.184 200.705 1.00 64.22  ? 244 GLU   B O      1 
ATOM   2783 C CB     . GLU   E 1 232 ? 233.804 228.209 201.015 1.00 59.36  ? 244 GLU   B CB     1 
ATOM   2784 C CG     . GLU   E 1 232 ? 233.927 229.587 201.636 1.00 58.69  ? 244 GLU   B CG     1 
ATOM   2785 C CD     . GLU   E 1 232 ? 234.730 229.575 202.919 1.00 63.97  ? 244 GLU   B CD     1 
ATOM   2786 O OE1    . GLU   E 1 232 ? 234.592 228.609 203.696 1.00 66.25  ? 244 GLU   B OE1    1 
ATOM   2787 O OE2    . GLU   E 1 232 ? 235.497 230.532 203.152 1.00 67.48  ? 244 GLU   B OE2    1 
ATOM   2788 N N      . SER   E 1 233 ? 235.440 226.050 199.017 1.00 55.25  ? 245 SER   B N      1 
ATOM   2789 C CA     . SER   E 1 233 ? 235.218 224.896 198.153 1.00 60.63  ? 245 SER   B CA     1 
ATOM   2790 C C      . SER   E 1 233 ? 235.754 223.621 198.792 1.00 67.13  ? 245 SER   B C      1 
ATOM   2791 O O      . SER   E 1 233 ? 236.952 223.516 199.071 1.00 71.81  ? 245 SER   B O      1 
ATOM   2792 C CB     . SER   E 1 233 ? 235.870 225.116 196.788 1.00 67.57  ? 245 SER   B CB     1 
ATOM   2793 O OG     . SER   E 1 233 ? 237.281 225.030 196.880 1.00 70.12  ? 245 SER   B OG     1 
ATOM   2794 N N      . ARG   E 1 234 ? 234.872 222.647 199.026 1.00 65.26  ? 246 ARG   B N      1 
ATOM   2795 C CA     . ARG   E 1 234 ? 235.292 221.412 199.681 1.00 68.73  ? 246 ARG   B CA     1 
ATOM   2796 C C      . ARG   E 1 234 ? 236.112 220.533 198.744 1.00 70.08  ? 246 ARG   B C      1 
ATOM   2797 O O      . ARG   E 1 234 ? 237.055 219.863 199.180 1.00 71.53  ? 246 ARG   B O      1 
ATOM   2798 C CB     . ARG   E 1 234 ? 234.072 220.652 200.198 1.00 82.30  ? 246 ARG   B CB     1 
ATOM   2799 C CG     . ARG   E 1 234 ? 233.304 221.386 201.282 1.00 87.67  ? 246 ARG   B CG     1 
ATOM   2800 C CD     . ARG   E 1 234 ? 234.218 221.764 202.432 1.00 81.39  ? 246 ARG   B CD     1 
ATOM   2801 N NE     . ARG   E 1 234 ? 234.981 220.625 202.924 1.00 78.10  ? 246 ARG   B NE     1 
ATOM   2802 C CZ     . ARG   E 1 234 ? 235.878 220.695 203.896 1.00 79.63  ? 246 ARG   B CZ     1 
ATOM   2803 N NH1    . ARG   E 1 234 ? 236.151 221.838 204.503 1.00 79.27  ? 246 ARG   B NH1    1 
ATOM   2804 N NH2    . ARG   E 1 234 ? 236.519 219.590 204.269 1.00 82.49  ? 246 ARG   B NH2    1 
ATOM   2805 N N      . ASN   E 1 235 ? 235.761 220.510 197.458 1.00 68.90  ? 247 ASN   B N      1 
ATOM   2806 C CA     . ASN   E 1 235 ? 236.493 219.760 196.439 1.00 65.18  ? 247 ASN   B CA     1 
ATOM   2807 C C      . ASN   E 1 235 ? 236.828 220.762 195.340 1.00 70.67  ? 247 ASN   B C      1 
ATOM   2808 O O      . ASN   E 1 235 ? 236.062 220.933 194.379 1.00 76.29  ? 247 ASN   B O      1 
ATOM   2809 C CB     . ASN   E 1 235 ? 235.682 218.564 195.935 1.00 66.91  ? 247 ASN   B CB     1 
ATOM   2810 C CG     . ASN   E 1 235 ? 236.500 217.587 195.093 1.00 70.67  ? 247 ASN   B CG     1 
ATOM   2811 O OD1    . ASN   E 1 235 ? 237.701 217.413 195.287 1.00 78.93  ? 247 ASN   B OD1    1 
ATOM   2812 N ND2    . ASN   E 1 235 ? 235.834 216.941 194.145 1.00 66.26  ? 247 ASN   B ND2    1 
ATOM   2813 N N      . PRO   E 1 236 ? 237.929 221.495 195.484 1.00 65.28  ? 248 PRO   B N      1 
ATOM   2814 C CA     . PRO   E 1 236 ? 238.284 222.488 194.467 1.00 60.18  ? 248 PRO   B CA     1 
ATOM   2815 C C      . PRO   E 1 236 ? 238.616 221.829 193.137 1.00 59.23  ? 248 PRO   B C      1 
ATOM   2816 O O      . PRO   E 1 236 ? 239.183 220.737 193.081 1.00 59.47  ? 248 PRO   B O      1 
ATOM   2817 C CB     . PRO   E 1 236 ? 239.506 223.191 195.068 1.00 60.92  ? 248 PRO   B CB     1 
ATOM   2818 C CG     . PRO   E 1 236 ? 240.062 222.211 196.043 1.00 60.77  ? 248 PRO   B CG     1 
ATOM   2819 C CD     . PRO   E 1 236 ? 238.883 221.481 196.603 1.00 62.11  ? 248 PRO   B CD     1 
ATOM   2820 N N      . GLY   E 1 237 ? 238.253 222.513 192.057 1.00 56.57  ? 249 GLY   B N      1 
ATOM   2821 C CA     . GLY   E 1 237 ? 238.508 222.008 190.725 1.00 53.50  ? 249 GLY   B CA     1 
ATOM   2822 C C      . GLY   E 1 237 ? 238.901 223.098 189.752 1.00 54.58  ? 249 GLY   B C      1 
ATOM   2823 O O      . GLY   E 1 237 ? 239.640 224.019 190.109 1.00 58.09  ? 249 GLY   B O      1 
ATOM   2824 N N      . ASN   E 1 238 ? 238.408 223.008 188.516 1.00 52.43  ? 250 ASN   B N      1 
ATOM   2825 C CA     . ASN   E 1 238 ? 238.763 224.005 187.513 1.00 50.85  ? 250 ASN   B CA     1 
ATOM   2826 C C      . ASN   E 1 238 ? 238.170 225.369 187.839 1.00 51.81  ? 250 ASN   B C      1 
ATOM   2827 O O      . ASN   E 1 238 ? 238.760 226.396 187.490 1.00 53.97  ? 250 ASN   B O      1 
ATOM   2828 C CB     . ASN   E 1 238 ? 238.307 223.547 186.128 1.00 50.63  ? 250 ASN   B CB     1 
ATOM   2829 C CG     . ASN   E 1 238 ? 239.443 222.987 185.297 1.00 54.58  ? 250 ASN   B CG     1 
ATOM   2830 O OD1    . ASN   E 1 238 ? 240.289 222.250 185.799 1.00 51.28  ? 250 ASN   B OD1    1 
ATOM   2831 N ND2    . ASN   E 1 238 ? 239.465 223.332 184.016 1.00 59.65  ? 250 ASN   B ND2    1 
ATOM   2832 N N      . ALA   E 1 239 ? 237.012 225.403 188.502 1.00 53.52  ? 251 ALA   B N      1 
ATOM   2833 C CA     . ALA   E 1 239 ? 236.386 226.682 188.819 1.00 52.23  ? 251 ALA   B CA     1 
ATOM   2834 C C      . ALA   E 1 239 ? 237.288 227.532 189.704 1.00 51.42  ? 251 ALA   B C      1 
ATOM   2835 O O      . ALA   E 1 239 ? 237.465 228.730 189.452 1.00 52.85  ? 251 ALA   B O      1 
ATOM   2836 C CB     . ALA   E 1 239 ? 235.033 226.453 189.491 1.00 53.47  ? 251 ALA   B CB     1 
ATOM   2837 N N      . GLU   E 1 240 ? 237.868 226.933 190.746 1.00 49.49  ? 252 GLU   B N      1 
ATOM   2838 C CA     . GLU   E 1 240 ? 238.834 227.655 191.565 1.00 50.49  ? 252 GLU   B CA     1 
ATOM   2839 C C      . GLU   E 1 240 ? 240.135 227.892 190.813 1.00 50.75  ? 252 GLU   B C      1 
ATOM   2840 O O      . GLU   E 1 240 ? 240.795 228.915 191.023 1.00 49.18  ? 252 GLU   B O      1 
ATOM   2841 C CB     . GLU   E 1 240 ? 239.103 226.892 192.860 1.00 56.92  ? 252 GLU   B CB     1 
ATOM   2842 C CG     . GLU   E 1 240 ? 237.854 226.540 193.646 1.00 64.88  ? 252 GLU   B CG     1 
ATOM   2843 C CD     . GLU   E 1 240 ? 237.242 225.225 193.206 1.00 68.45  ? 252 GLU   B CD     1 
ATOM   2844 O OE1    . GLU   E 1 240 ? 237.537 224.780 192.078 1.00 69.53  ? 252 GLU   B OE1    1 
ATOM   2845 O OE2    . GLU   E 1 240 ? 236.470 224.635 193.989 1.00 65.41  ? 252 GLU   B OE2    1 
ATOM   2846 N N      . PHE   E 1 241 ? 240.522 226.956 189.944 1.00 52.45  ? 253 PHE   B N      1 
ATOM   2847 C CA     . PHE   E 1 241 ? 241.707 227.147 189.116 1.00 47.46  ? 253 PHE   B CA     1 
ATOM   2848 C C      . PHE   E 1 241 ? 241.605 228.445 188.323 1.00 47.54  ? 253 PHE   B C      1 
ATOM   2849 O O      . PHE   E 1 241 ? 242.505 229.290 188.375 1.00 49.89  ? 253 PHE   B O      1 
ATOM   2850 C CB     . PHE   E 1 241 ? 241.873 225.942 188.186 1.00 51.26  ? 253 PHE   B CB     1 
ATOM   2851 C CG     . PHE   E 1 241 ? 243.107 225.978 187.323 1.00 47.85  ? 253 PHE   B CG     1 
ATOM   2852 C CD1    . PHE   E 1 241 ? 244.060 226.970 187.463 1.00 52.16  ? 253 PHE   B CD1    1 
ATOM   2853 C CD2    . PHE   E 1 241 ? 243.297 225.014 186.349 1.00 47.14  ? 253 PHE   B CD2    1 
ATOM   2854 C CE1    . PHE   E 1 241 ? 245.181 226.990 186.657 1.00 54.48  ? 253 PHE   B CE1    1 
ATOM   2855 C CE2    . PHE   E 1 241 ? 244.413 225.031 185.541 1.00 45.16  ? 253 PHE   B CE2    1 
ATOM   2856 C CZ     . PHE   E 1 241 ? 245.356 226.018 185.695 1.00 49.09  ? 253 PHE   B CZ     1 
ATOM   2857 N N      . GLU   E 1 242 ? 240.503 228.629 187.594 1.00 47.34  ? 254 GLU   B N      1 
ATOM   2858 C CA     . GLU   E 1 242 ? 240.327 229.857 186.825 1.00 47.24  ? 254 GLU   B CA     1 
ATOM   2859 C C      . GLU   E 1 242 ? 240.143 231.066 187.733 1.00 46.29  ? 254 GLU   B C      1 
ATOM   2860 O O      . GLU   E 1 242 ? 240.645 232.154 187.433 1.00 46.47  ? 254 GLU   B O      1 
ATOM   2861 C CB     . GLU   E 1 242 ? 239.148 229.721 185.865 1.00 47.62  ? 254 GLU   B CB     1 
ATOM   2862 C CG     . GLU   E 1 242 ? 238.972 228.339 185.278 1.00 50.68  ? 254 GLU   B CG     1 
ATOM   2863 C CD     . GLU   E 1 242 ? 240.087 227.981 184.320 1.00 57.96  ? 254 GLU   B CD     1 
ATOM   2864 O OE1    . GLU   E 1 242 ? 239.998 226.924 183.665 1.00 64.05  ? 254 GLU   B OE1    1 
ATOM   2865 O OE2    . GLU   E 1 242 ? 241.058 228.757 184.224 1.00 56.89  ? 254 GLU   B OE2    1 
ATOM   2866 N N      . ASP   E 1 243 ? 239.420 230.900 188.841 1.00 47.31  ? 255 ASP   B N      1 
ATOM   2867 C CA     . ASP   E 1 243 ? 239.168 232.027 189.733 1.00 47.56  ? 255 ASP   B CA     1 
ATOM   2868 C C      . ASP   E 1 243 ? 240.468 232.573 190.311 1.00 45.46  ? 255 ASP   B C      1 
ATOM   2869 O O      . ASP   E 1 243 ? 240.664 233.792 190.380 1.00 46.67  ? 255 ASP   B O      1 
ATOM   2870 C CB     . ASP   E 1 243 ? 238.219 231.602 190.852 1.00 54.82  ? 255 ASP   B CB     1 
ATOM   2871 C CG     . ASP   E 1 243 ? 236.781 231.993 190.575 1.00 66.50  ? 255 ASP   B CG     1 
ATOM   2872 O OD1    . ASP   E 1 243 ? 235.955 231.086 190.352 1.00 70.79  ? 255 ASP   B OD1    1 
ATOM   2873 O OD2    . ASP   E 1 243 ? 236.464 233.199 190.587 1.00 69.61  ? 255 ASP   B OD2    1 
ATOM   2874 N N      . LEU   E 1 244 ? 241.369 231.683 190.733 1.00 45.87  ? 256 LEU   B N      1 
ATOM   2875 C CA     . LEU   E 1 244 ? 242.663 232.125 191.238 1.00 41.82  ? 256 LEU   B CA     1 
ATOM   2876 C C      . LEU   E 1 244 ? 243.494 232.790 190.149 1.00 41.62  ? 256 LEU   B C      1 
ATOM   2877 O O      . LEU   E 1 244 ? 244.195 233.770 190.421 1.00 40.45  ? 256 LEU   B O      1 
ATOM   2878 C CB     . LEU   E 1 244 ? 243.423 230.946 191.840 1.00 42.13  ? 256 LEU   B CB     1 
ATOM   2879 C CG     . LEU   E 1 244 ? 243.032 230.510 193.251 1.00 41.61  ? 256 LEU   B CG     1 
ATOM   2880 C CD1    . LEU   E 1 244 ? 243.637 229.153 193.559 1.00 39.76  ? 256 LEU   B CD1    1 
ATOM   2881 C CD2    . LEU   E 1 244 ? 243.484 231.541 194.271 1.00 36.92  ? 256 LEU   B CD2    1 
ATOM   2882 N N      . ILE   E 1 245 ? 243.431 232.273 188.920 1.00 44.07  ? 257 ILE   B N      1 
ATOM   2883 C CA     . ILE   E 1 245 ? 244.160 232.885 187.814 1.00 41.80  ? 257 ILE   B CA     1 
ATOM   2884 C C      . ILE   E 1 245 ? 243.699 234.322 187.606 1.00 40.77  ? 257 ILE   B C      1 
ATOM   2885 O O      . ILE   E 1 245 ? 244.503 235.214 187.313 1.00 39.34  ? 257 ILE   B O      1 
ATOM   2886 C CB     . ILE   E 1 245 ? 243.991 232.046 186.534 1.00 41.37  ? 257 ILE   B CB     1 
ATOM   2887 C CG1    . ILE   E 1 245 ? 244.917 230.831 186.566 1.00 39.75  ? 257 ILE   B CG1    1 
ATOM   2888 C CG2    . ILE   E 1 245 ? 244.281 232.888 185.311 1.00 41.56  ? 257 ILE   B CG2    1 
ATOM   2889 C CD1    . ILE   E 1 245 ? 246.372 231.191 186.657 1.00 47.41  ? 257 ILE   B CD1    1 
ATOM   2890 N N      . PHE   E 1 246 ? 242.394 234.565 187.741 1.00 42.73  ? 258 PHE   B N      1 
ATOM   2891 C CA     . PHE   E 1 246 ? 241.883 235.929 187.667 1.00 44.06  ? 258 PHE   B CA     1 
ATOM   2892 C C      . PHE   E 1 246 ? 242.418 236.774 188.815 1.00 44.88  ? 258 PHE   B C      1 
ATOM   2893 O O      . PHE   E 1 246 ? 242.748 237.951 188.632 1.00 45.76  ? 258 PHE   B O      1 
ATOM   2894 C CB     . PHE   E 1 246 ? 240.355 235.912 187.675 1.00 45.87  ? 258 PHE   B CB     1 
ATOM   2895 C CG     . PHE   E 1 246 ? 239.733 237.274 187.720 1.00 46.88  ? 258 PHE   B CG     1 
ATOM   2896 C CD1    . PHE   E 1 246 ? 239.598 238.026 186.569 1.00 46.09  ? 258 PHE   B CD1    1 
ATOM   2897 C CD2    . PHE   E 1 246 ? 239.275 237.800 188.914 1.00 46.40  ? 258 PHE   B CD2    1 
ATOM   2898 C CE1    . PHE   E 1 246 ? 239.024 239.275 186.609 1.00 50.46  ? 258 PHE   B CE1    1 
ATOM   2899 C CE2    . PHE   E 1 246 ? 238.702 239.049 188.959 1.00 47.43  ? 258 PHE   B CE2    1 
ATOM   2900 C CZ     . PHE   E 1 246 ? 238.576 239.787 187.805 1.00 50.95  ? 258 PHE   B CZ     1 
ATOM   2901 N N      . LEU   E 1 247 ? 242.512 236.185 190.007 1.00 43.27  ? 259 LEU   B N      1 
ATOM   2902 C CA     . LEU   E 1 247 ? 243.031 236.917 191.157 1.00 43.08  ? 259 LEU   B CA     1 
ATOM   2903 C C      . LEU   E 1 247 ? 244.468 237.364 190.924 1.00 43.43  ? 259 LEU   B C      1 
ATOM   2904 O O      . LEU   E 1 247 ? 244.834 238.498 191.252 1.00 45.22  ? 259 LEU   B O      1 
ATOM   2905 C CB     . LEU   E 1 247 ? 242.933 236.048 192.409 1.00 43.63  ? 259 LEU   B CB     1 
ATOM   2906 C CG     . LEU   E 1 247 ? 241.823 236.393 193.399 1.00 43.67  ? 259 LEU   B CG     1 
ATOM   2907 C CD1    . LEU   E 1 247 ? 241.980 235.583 194.669 1.00 42.17  ? 259 LEU   B CD1    1 
ATOM   2908 C CD2    . LEU   E 1 247 ? 241.828 237.877 193.706 1.00 46.43  ? 259 LEU   B CD2    1 
ATOM   2909 N N      . ALA   E 1 248 ? 245.301 236.485 190.362 1.00 43.33  ? 260 ALA   B N      1 
ATOM   2910 C CA     . ALA   E 1 248 ? 246.685 236.853 190.083 1.00 42.41  ? 260 ALA   B CA     1 
ATOM   2911 C C      . ALA   E 1 248 ? 246.762 237.965 189.046 1.00 41.58  ? 260 ALA   B C      1 
ATOM   2912 O O      . ALA   E 1 248 ? 247.547 238.909 189.192 1.00 39.96  ? 260 ALA   B O      1 
ATOM   2913 C CB     . ALA   E 1 248 ? 247.470 235.628 189.618 1.00 43.46  ? 260 ALA   B CB     1 
ATOM   2914 N N      . ARG   E 1 249 ? 245.953 237.873 187.990 1.00 43.06  ? 261 ARG   B N      1 
ATOM   2915 C CA     . ARG   E 1 249 ? 245.941 238.922 186.978 1.00 43.35  ? 261 ARG   B CA     1 
ATOM   2916 C C      . ARG   E 1 249 ? 245.500 240.250 187.577 1.00 41.30  ? 261 ARG   B C      1 
ATOM   2917 O O      . ARG   E 1 249 ? 245.994 241.313 187.186 1.00 40.56  ? 261 ARG   B O      1 
ATOM   2918 C CB     . ARG   E 1 249 ? 245.025 238.518 185.823 1.00 42.36  ? 261 ARG   B CB     1 
ATOM   2919 C CG     . ARG   E 1 249 ? 245.337 239.202 184.510 1.00 40.51  ? 261 ARG   B CG     1 
ATOM   2920 C CD     . ARG   E 1 249 ? 244.994 238.303 183.335 1.00 41.57  ? 261 ARG   B CD     1 
ATOM   2921 N NE     . ARG   E 1 249 ? 245.558 236.969 183.489 1.00 43.60  ? 261 ARG   B NE     1 
ATOM   2922 C CZ     . ARG   E 1 249 ? 245.292 235.945 182.689 1.00 44.44  ? 261 ARG   B CZ     1 
ATOM   2923 N NH1    . ARG   E 1 249 ? 244.470 236.067 181.661 1.00 44.61  ? 261 ARG   B NH1    1 
ATOM   2924 N NH2    . ARG   E 1 249 ? 245.868 234.771 182.925 1.00 49.94  ? 261 ARG   B NH2    1 
ATOM   2925 N N      . SER   E 1 250 ? 244.572 240.206 188.534 1.00 40.31  ? 262 SER   B N      1 
ATOM   2926 C CA     . SER   E 1 250 ? 244.118 241.427 189.188 1.00 40.62  ? 262 SER   B CA     1 
ATOM   2927 C C      . SER   E 1 250 ? 245.207 242.043 190.055 1.00 38.99  ? 262 SER   B C      1 
ATOM   2928 O O      . SER   E 1 250 ? 245.230 243.264 190.242 1.00 37.45  ? 262 SER   B O      1 
ATOM   2929 C CB     . SER   E 1 250 ? 242.877 241.136 190.028 1.00 43.66  ? 262 SER   B CB     1 
ATOM   2930 O OG     . SER   E 1 250 ? 243.209 240.366 191.168 1.00 45.43  ? 262 SER   B OG     1 
ATOM   2931 N N      . ALA   E 1 251 ? 246.113 241.223 190.593 1.00 39.22  ? 263 ALA   B N      1 
ATOM   2932 C CA     . ALA   E 1 251 ? 247.161 241.739 191.463 1.00 37.47  ? 263 ALA   B CA     1 
ATOM   2933 C C      . ALA   E 1 251 ? 248.144 242.635 190.724 1.00 38.63  ? 263 ALA   B C      1 
ATOM   2934 O O      . ALA   E 1 251 ? 248.876 243.393 191.369 1.00 37.88  ? 263 ALA   B O      1 
ATOM   2935 C CB     . ALA   E 1 251 ? 247.911 240.584 192.126 1.00 38.74  ? 263 ALA   B CB     1 
ATOM   2936 N N      . LEU   E 1 252 ? 248.185 242.565 189.393 1.00 41.23  ? 264 LEU   B N      1 
ATOM   2937 C CA     . LEU   E 1 252 ? 249.067 243.440 188.632 1.00 38.31  ? 264 LEU   B CA     1 
ATOM   2938 C C      . LEU   E 1 252 ? 248.653 244.900 188.736 1.00 39.19  ? 264 LEU   B C      1 
ATOM   2939 O O      . LEU   E 1 252 ? 249.517 245.781 188.709 1.00 40.16  ? 264 LEU   B O      1 
ATOM   2940 C CB     . LEU   E 1 252 ? 249.095 243.013 187.165 1.00 37.87  ? 264 LEU   B CB     1 
ATOM   2941 C CG     . LEU   E 1 252 ? 249.494 241.566 186.880 1.00 37.15  ? 264 LEU   B CG     1 
ATOM   2942 C CD1    . LEU   E 1 252 ? 249.044 241.152 185.492 1.00 36.26  ? 264 LEU   B CD1    1 
ATOM   2943 C CD2    . LEU   E 1 252 ? 250.992 241.391 187.030 1.00 38.97  ? 264 LEU   B CD2    1 
ATOM   2944 N N      . ILE   E 1 253 ? 247.356 245.170 188.860 1.00 39.57  ? 265 ILE   B N      1 
ATOM   2945 C CA     . ILE   E 1 253 ? 246.831 246.527 188.972 1.00 38.43  ? 265 ILE   B CA     1 
ATOM   2946 C C      . ILE   E 1 253 ? 246.537 246.878 190.425 1.00 37.60  ? 265 ILE   B C      1 
ATOM   2947 O O      . ILE   E 1 253 ? 246.998 247.902 190.931 1.00 36.78  ? 265 ILE   B O      1 
ATOM   2948 C CB     . ILE   E 1 253 ? 245.576 246.708 188.090 1.00 38.38  ? 265 ILE   B CB     1 
ATOM   2949 C CG1    . ILE   E 1 253 ? 245.886 246.361 186.635 1.00 37.17  ? 265 ILE   B CG1    1 
ATOM   2950 C CG2    . ILE   E 1 253 ? 245.044 248.124 188.203 1.00 44.25  ? 265 ILE   B CG2    1 
ATOM   2951 C CD1    . ILE   E 1 253 ? 247.259 246.781 186.200 1.00 47.59  ? 265 ILE   B CD1    1 
ATOM   2952 N N      . LEU   E 1 254 ? 245.759 246.040 191.110 1.00 39.13  ? 266 LEU   B N      1 
ATOM   2953 C CA     . LEU   E 1 254 ? 245.472 246.209 192.533 1.00 39.62  ? 266 LEU   B CA     1 
ATOM   2954 C C      . LEU   E 1 254 ? 246.476 245.383 193.337 1.00 40.26  ? 266 LEU   B C      1 
ATOM   2955 O O      . LEU   E 1 254 ? 246.197 244.287 193.826 1.00 45.53  ? 266 LEU   B O      1 
ATOM   2956 C CB     . LEU   E 1 254 ? 244.035 245.810 192.832 1.00 42.80  ? 266 LEU   B CB     1 
ATOM   2957 C CG     . LEU   E 1 254 ? 243.005 246.377 191.856 1.00 40.20  ? 266 LEU   B CG     1 
ATOM   2958 C CD1    . LEU   E 1 254 ? 241.624 245.824 192.141 1.00 44.89  ? 266 LEU   B CD1    1 
ATOM   2959 C CD2    . LEU   E 1 254 ? 242.999 247.892 191.931 1.00 42.23  ? 266 LEU   B CD2    1 
ATOM   2960 N N      . ARG   E 1 255 ? 247.675 245.941 193.465 1.00 38.55  ? 267 ARG   B N      1 
ATOM   2961 C CA     . ARG   E 1 255 ? 248.789 245.198 194.035 1.00 40.23  ? 267 ARG   B CA     1 
ATOM   2962 C C      . ARG   E 1 255 ? 248.531 244.846 195.493 1.00 41.83  ? 267 ARG   B C      1 
ATOM   2963 O O      . ARG   E 1 255 ? 247.919 245.614 196.239 1.00 45.53  ? 267 ARG   B O      1 
ATOM   2964 C CB     . ARG   E 1 255 ? 250.074 246.010 193.909 1.00 38.61  ? 267 ARG   B CB     1 
ATOM   2965 C CG     . ARG   E 1 255 ? 250.399 246.400 192.485 1.00 39.01  ? 267 ARG   B CG     1 
ATOM   2966 C CD     . ARG   E 1 255 ? 251.457 247.478 192.438 1.00 40.40  ? 267 ARG   B CD     1 
ATOM   2967 N NE     . ARG   E 1 255 ? 251.769 247.864 191.068 1.00 42.31  ? 267 ARG   B NE     1 
ATOM   2968 C CZ     . ARG   E 1 255 ? 251.109 248.786 190.383 1.00 42.55  ? 267 ARG   B CZ     1 
ATOM   2969 N NH1    . ARG   E 1 255 ? 250.099 249.451 190.917 1.00 39.40  ? 267 ARG   B NH1    1 
ATOM   2970 N NH2    . ARG   E 1 255 ? 251.474 249.050 189.133 1.00 47.10  ? 267 ARG   B NH2    1 
ATOM   2971 N N      . GLY   E 1 256 ? 249.001 243.667 195.894 1.00 39.34  ? 268 GLY   B N      1 
ATOM   2972 C CA     . GLY   E 1 256 ? 248.890 243.228 197.265 1.00 39.34  ? 268 GLY   B CA     1 
ATOM   2973 C C      . GLY   E 1 256 ? 250.000 243.775 198.139 1.00 42.57  ? 268 GLY   B C      1 
ATOM   2974 O O      . GLY   E 1 256 ? 250.867 244.534 197.709 1.00 46.20  ? 268 GLY   B O      1 
ATOM   2975 N N      . SER   E 1 257 ? 249.966 243.367 199.402 1.00 43.73  ? 269 SER   B N      1 
ATOM   2976 C CA     . SER   E 1 257 ? 250.934 243.808 200.403 1.00 41.14  ? 269 SER   B CA     1 
ATOM   2977 C C      . SER   E 1 257 ? 252.000 242.728 200.541 1.00 42.05  ? 269 SER   B C      1 
ATOM   2978 O O      . SER   E 1 257 ? 251.761 241.676 201.138 1.00 46.06  ? 269 SER   B O      1 
ATOM   2979 C CB     . SER   E 1 257 ? 250.245 244.087 201.734 1.00 42.82  ? 269 SER   B CB     1 
ATOM   2980 O OG     . SER   E 1 257 ? 249.909 245.456 201.853 1.00 52.04  ? 269 SER   B OG     1 
ATOM   2981 N N      . VAL   E 1 258 ? 253.178 242.991 199.989 1.00 41.80  ? 270 VAL   B N      1 
ATOM   2982 C CA     . VAL   E 1 258 ? 254.310 242.075 200.058 1.00 41.38  ? 270 VAL   B CA     1 
ATOM   2983 C C      . VAL   E 1 258 ? 255.392 242.737 200.895 1.00 42.28  ? 270 VAL   B C      1 
ATOM   2984 O O      . VAL   E 1 258 ? 255.825 243.855 200.592 1.00 43.74  ? 270 VAL   B O      1 
ATOM   2985 C CB     . VAL   E 1 258 ? 254.834 241.714 198.661 1.00 39.24  ? 270 VAL   B CB     1 
ATOM   2986 C CG1    . VAL   E 1 258 ? 256.161 240.990 198.768 1.00 41.90  ? 270 VAL   B CG1    1 
ATOM   2987 C CG2    . VAL   E 1 258 ? 253.820 240.865 197.921 1.00 35.57  ? 270 VAL   B CG2    1 
ATOM   2988 N N      . ALA   E 1 259 ? 255.823 242.055 201.952 1.00 39.56  ? 271 ALA   B N      1 
ATOM   2989 C CA     . ALA   E 1 259 ? 256.874 242.595 202.800 1.00 38.69  ? 271 ALA   B CA     1 
ATOM   2990 C C      . ALA   E 1 259 ? 258.213 242.544 202.080 1.00 40.89  ? 271 ALA   B C      1 
ATOM   2991 O O      . ALA   E 1 259 ? 258.560 241.544 201.446 1.00 43.27  ? 271 ALA   B O      1 
ATOM   2992 C CB     . ALA   E 1 259 ? 256.951 241.821 204.113 1.00 38.61  ? 271 ALA   B CB     1 
ATOM   2993 N N      . HIS   E 1 260 ? 258.971 243.631 202.184 1.00 40.12  ? 272 HIS   B N      1 
ATOM   2994 C CA     . HIS   E 1 260 ? 260.289 243.728 201.571 1.00 40.50  ? 272 HIS   B CA     1 
ATOM   2995 C C      . HIS   E 1 260 ? 261.311 243.966 202.668 1.00 41.98  ? 272 HIS   B C      1 
ATOM   2996 O O      . HIS   E 1 260 ? 261.212 244.952 203.406 1.00 44.94  ? 272 HIS   B O      1 
ATOM   2997 C CB     . HIS   E 1 260 ? 260.337 244.853 200.534 1.00 40.38  ? 272 HIS   B CB     1 
ATOM   2998 C CG     . HIS   E 1 260 ? 259.551 244.565 199.294 1.00 41.49  ? 272 HIS   B CG     1 
ATOM   2999 N ND1    . HIS   E 1 260 ? 258.196 244.801 199.199 1.00 40.56  ? 272 HIS   B ND1    1 
ATOM   3000 C CD2    . HIS   E 1 260 ? 259.927 244.051 198.099 1.00 41.54  ? 272 HIS   B CD2    1 
ATOM   3001 C CE1    . HIS   E 1 260 ? 257.774 244.452 197.998 1.00 37.20  ? 272 HIS   B CE1    1 
ATOM   3002 N NE2    . HIS   E 1 260 ? 258.804 243.995 197.310 1.00 36.67  ? 272 HIS   B NE2    1 
ATOM   3003 N N      . LYS   E 1 261 ? 262.286 243.067 202.775 1.00 39.57  ? 273 LYS   B N      1 
ATOM   3004 C CA     . LYS   E 1 261 ? 263.332 243.154 203.782 1.00 40.52  ? 273 LYS   B CA     1 
ATOM   3005 C C      . LYS   E 1 261 ? 264.693 243.034 203.116 1.00 41.07  ? 273 LYS   B C      1 
ATOM   3006 O O      . LYS   E 1 261 ? 264.844 242.330 202.114 1.00 42.49  ? 273 LYS   B O      1 
ATOM   3007 C CB     . LYS   E 1 261 ? 263.176 242.063 204.847 1.00 40.86  ? 273 LYS   B CB     1 
ATOM   3008 C CG     . LYS   E 1 261 ? 261.819 242.038 205.522 1.00 39.02  ? 273 LYS   B CG     1 
ATOM   3009 C CD     . LYS   E 1 261 ? 261.473 240.643 206.005 1.00 39.12  ? 273 LYS   B CD     1 
ATOM   3010 C CE     . LYS   E 1 261 ? 260.252 240.663 206.901 1.00 34.60  ? 273 LYS   B CE     1 
ATOM   3011 N NZ     . LYS   E 1 261 ? 260.122 241.960 207.613 1.00 39.14  ? 273 LYS   B NZ     1 
ATOM   3012 N N      . SER   E 1 262 ? 265.680 243.729 203.676 1.00 39.75  ? 274 SER   B N      1 
ATOM   3013 C CA     . SER   E 1 262 ? 267.051 243.697 203.169 1.00 38.81  ? 274 SER   B CA     1 
ATOM   3014 C C      . SER   E 1 262 ? 267.823 242.657 203.973 1.00 40.89  ? 274 SER   B C      1 
ATOM   3015 O O      . SER   E 1 262 ? 268.309 242.926 205.071 1.00 40.94  ? 274 SER   B O      1 
ATOM   3016 C CB     . SER   E 1 262 ? 267.698 245.073 203.258 1.00 38.96  ? 274 SER   B CB     1 
ATOM   3017 O OG     . SER   E 1 262 ? 266.776 246.093 202.926 1.00 45.32  ? 274 SER   B OG     1 
ATOM   3018 N N      . CYS   E 1 263 ? 267.933 241.455 203.415 1.00 42.29  ? 275 CYS   B N      1 
ATOM   3019 C CA     . CYS   E 1 263 ? 268.660 240.357 204.040 1.00 40.29  ? 275 CYS   B CA     1 
ATOM   3020 C C      . CYS   E 1 263 ? 270.023 240.243 203.366 1.00 41.83  ? 275 CYS   B C      1 
ATOM   3021 O O      . CYS   E 1 263 ? 270.116 239.846 202.201 1.00 42.97  ? 275 CYS   B O      1 
ATOM   3022 C CB     . CYS   E 1 263 ? 267.873 239.054 203.929 1.00 40.17  ? 275 CYS   B CB     1 
ATOM   3023 S SG     . CYS   E 1 263 ? 266.241 239.114 204.696 1.00 52.29  ? 275 CYS   B SG     1 
ATOM   3024 N N      . LEU   E 1 264 ? 271.073 240.594 204.099 1.00 40.90  ? 276 LEU   B N      1 
ATOM   3025 C CA     . LEU   E 1 264 ? 272.418 240.646 203.554 1.00 40.95  ? 276 LEU   B CA     1 
ATOM   3026 C C      . LEU   E 1 264 ? 273.121 239.298 203.680 1.00 41.17  ? 276 LEU   B C      1 
ATOM   3027 O O      . LEU   E 1 264 ? 272.703 238.434 204.454 1.00 40.27  ? 276 LEU   B O      1 
ATOM   3028 C CB     . LEU   E 1 264 ? 273.228 241.718 204.271 1.00 40.26  ? 276 LEU   B CB     1 
ATOM   3029 C CG     . LEU   E 1 264 ? 272.643 243.128 204.243 1.00 38.97  ? 276 LEU   B CG     1 
ATOM   3030 C CD1    . LEU   E 1 264 ? 273.649 244.128 204.778 1.00 39.57  ? 276 LEU   B CD1    1 
ATOM   3031 C CD2    . LEU   E 1 264 ? 272.209 243.496 202.838 1.00 41.60  ? 276 LEU   B CD2    1 
ATOM   3032 N N      . PRO   E 1 265 ? 274.194 239.094 202.921 1.00 41.67  ? 277 PRO   B N      1 
ATOM   3033 C CA     . PRO   E 1 265 ? 274.978 237.864 203.069 1.00 39.36  ? 277 PRO   B CA     1 
ATOM   3034 C C      . PRO   E 1 265 ? 275.665 237.804 204.423 1.00 41.93  ? 277 PRO   B C      1 
ATOM   3035 O O      . PRO   E 1 265 ? 275.972 238.827 205.039 1.00 44.27  ? 277 PRO   B O      1 
ATOM   3036 C CB     . PRO   E 1 265 ? 276.000 237.955 201.930 1.00 39.64  ? 277 PRO   B CB     1 
ATOM   3037 C CG     . PRO   E 1 265 ? 276.093 239.410 201.624 1.00 39.72  ? 277 PRO   B CG     1 
ATOM   3038 C CD     . PRO   E 1 265 ? 274.720 239.959 201.852 1.00 41.35  ? 277 PRO   B CD     1 
ATOM   3039 N N      . ALA   E 1 266 ? 275.911 236.576 204.883 1.00 40.29  ? 278 ALA   B N      1 
ATOM   3040 C CA     . ALA   E 1 266 ? 276.497 236.385 206.204 1.00 38.48  ? 278 ALA   B CA     1 
ATOM   3041 C C      . ALA   E 1 266 ? 277.900 236.966 206.309 1.00 38.64  ? 278 ALA   B C      1 
ATOM   3042 O O      . ALA   E 1 266 ? 278.364 237.232 207.423 1.00 41.23  ? 278 ALA   B O      1 
ATOM   3043 C CB     . ALA   E 1 266 ? 276.518 234.899 206.559 1.00 39.91  ? 278 ALA   B CB     1 
ATOM   3044 N N      . CYS   E 1 267 ? 278.589 237.164 205.183 1.00 38.46  ? 279 CYS   B N      1 
ATOM   3045 C CA     . CYS   E 1 267 ? 279.921 237.758 205.234 1.00 38.40  ? 279 CYS   B CA     1 
ATOM   3046 C C      . CYS   E 1 267 ? 279.867 239.184 205.764 1.00 38.74  ? 279 CYS   B C      1 
ATOM   3047 O O      . CYS   E 1 267 ? 280.764 239.618 206.495 1.00 41.47  ? 279 CYS   B O      1 
ATOM   3048 C CB     . CYS   E 1 267 ? 280.569 237.721 203.850 1.00 35.92  ? 279 CYS   B CB     1 
ATOM   3049 S SG     . CYS   E 1 267 ? 279.436 238.004 202.479 1.00 54.21  ? 279 CYS   B SG     1 
ATOM   3050 N N      . VAL   E 1 268 ? 278.825 239.932 205.399 1.00 38.31  ? 280 VAL   B N      1 
ATOM   3051 C CA     . VAL   E 1 268 ? 278.677 241.298 205.892 1.00 39.43  ? 280 VAL   B CA     1 
ATOM   3052 C C      . VAL   E 1 268 ? 278.488 241.299 207.404 1.00 40.37  ? 280 VAL   B C      1 
ATOM   3053 O O      . VAL   E 1 268 ? 279.110 242.087 208.125 1.00 41.70  ? 280 VAL   B O      1 
ATOM   3054 C CB     . VAL   E 1 268 ? 277.512 242.002 205.173 1.00 41.51  ? 280 VAL   B CB     1 
ATOM   3055 C CG1    . VAL   E 1 268 ? 277.360 243.422 205.681 1.00 42.37  ? 280 VAL   B CG1    1 
ATOM   3056 C CG2    . VAL   E 1 268 ? 277.742 241.995 203.675 1.00 41.39  ? 280 VAL   B CG2    1 
ATOM   3057 N N      . TYR   E 1 269 ? 277.621 240.418 207.906 1.00 39.12  ? 281 TYR   B N      1 
ATOM   3058 C CA     . TYR   E 1 269 ? 277.415 240.329 209.348 1.00 39.32  ? 281 TYR   B CA     1 
ATOM   3059 C C      . TYR   E 1 269 ? 278.676 239.860 210.061 1.00 38.39  ? 281 TYR   B C      1 
ATOM   3060 O O      . TYR   E 1 269 ? 279.003 240.354 211.146 1.00 40.24  ? 281 TYR   B O      1 
ATOM   3061 C CB     . TYR   E 1 269 ? 276.245 239.397 209.659 1.00 37.66  ? 281 TYR   B CB     1 
ATOM   3062 C CG     . TYR   E 1 269 ? 274.951 239.779 208.980 1.00 38.77  ? 281 TYR   B CG     1 
ATOM   3063 C CD1    . TYR   E 1 269 ? 274.551 241.103 208.902 1.00 39.68  ? 281 TYR   B CD1    1 
ATOM   3064 C CD2    . TYR   E 1 269 ? 274.125 238.813 208.426 1.00 39.48  ? 281 TYR   B CD2    1 
ATOM   3065 C CE1    . TYR   E 1 269 ? 273.367 241.455 208.286 1.00 38.94  ? 281 TYR   B CE1    1 
ATOM   3066 C CE2    . TYR   E 1 269 ? 272.940 239.155 207.811 1.00 39.14  ? 281 TYR   B CE2    1 
ATOM   3067 C CZ     . TYR   E 1 269 ? 272.566 240.477 207.744 1.00 38.01  ? 281 TYR   B CZ     1 
ATOM   3068 O OH     . TYR   E 1 269 ? 271.386 240.821 207.129 1.00 37.49  ? 281 TYR   B OH     1 
ATOM   3069 N N      . GLY   E 1 270 ? 279.389 238.898 209.477 1.00 37.25  ? 282 GLY   B N      1 
ATOM   3070 C CA     . GLY   E 1 270 ? 280.606 238.414 210.107 1.00 37.33  ? 282 GLY   B CA     1 
ATOM   3071 C C      . GLY   E 1 270 ? 281.665 239.492 210.238 1.00 40.23  ? 282 GLY   B C      1 
ATOM   3072 O O      . GLY   E 1 270 ? 282.303 239.625 211.285 1.00 41.12  ? 282 GLY   B O      1 
ATOM   3073 N N      . SER   E 1 271 ? 281.865 240.277 209.179 1.00 39.63  ? 283 SER   B N      1 
ATOM   3074 C CA     . SER   E 1 271 ? 282.820 241.377 209.248 1.00 39.37  ? 283 SER   B CA     1 
ATOM   3075 C C      . SER   E 1 271 ? 282.393 242.412 210.282 1.00 41.20  ? 283 SER   B C      1 
ATOM   3076 O O      . SER   E 1 271 ? 283.227 242.937 211.028 1.00 45.18  ? 283 SER   B O      1 
ATOM   3077 C CB     . SER   E 1 271 ? 282.975 242.021 207.871 1.00 38.56  ? 283 SER   B CB     1 
ATOM   3078 O OG     . SER   E 1 271 ? 283.606 243.284 207.967 1.00 46.45  ? 283 SER   B OG     1 
ATOM   3079 N N      . ALA   E 1 272 ? 281.096 242.722 210.338 1.00 38.66  ? 284 ALA   B N      1 
ATOM   3080 C CA     . ALA   E 1 272 ? 280.612 243.701 211.304 1.00 39.19  ? 284 ALA   B CA     1 
ATOM   3081 C C      . ALA   E 1 272 ? 280.801 243.215 212.736 1.00 39.52  ? 284 ALA   B C      1 
ATOM   3082 O O      . ALA   E 1 272 ? 281.216 243.983 213.611 1.00 40.09  ? 284 ALA   B O      1 
ATOM   3083 C CB     . ALA   E 1 272 ? 279.142 244.017 211.035 1.00 41.04  ? 284 ALA   B CB     1 
ATOM   3084 N N      . VAL   E 1 273 ? 280.494 241.943 212.997 1.00 38.45  ? 285 VAL   B N      1 
ATOM   3085 C CA     . VAL   E 1 273 ? 280.625 241.416 214.352 1.00 38.69  ? 285 VAL   B CA     1 
ATOM   3086 C C      . VAL   E 1 273 ? 282.091 241.337 214.757 1.00 40.51  ? 285 VAL   B C      1 
ATOM   3087 O O      . VAL   E 1 273 ? 282.449 241.632 215.903 1.00 43.20  ? 285 VAL   B O      1 
ATOM   3088 C CB     . VAL   E 1 273 ? 279.932 240.047 214.463 1.00 38.84  ? 285 VAL   B CB     1 
ATOM   3089 C CG1    . VAL   E 1 273 ? 280.325 239.363 215.759 1.00 39.85  ? 285 VAL   B CG1    1 
ATOM   3090 C CG2    . VAL   E 1 273 ? 278.426 240.211 214.380 1.00 40.72  ? 285 VAL   B CG2    1 
ATOM   3091 N N      . ALA   E 1 274 ? 282.962 240.935 213.829 1.00 40.13  ? 286 ALA   B N      1 
ATOM   3092 C CA     . ALA   E 1 274 ? 284.386 240.870 214.137 1.00 38.25  ? 286 ALA   B CA     1 
ATOM   3093 C C      . ALA   E 1 274 ? 284.960 242.251 214.419 1.00 39.38  ? 286 ALA   B C      1 
ATOM   3094 O O      . ALA   E 1 274 ? 285.958 242.373 215.138 1.00 39.79  ? 286 ALA   B O      1 
ATOM   3095 C CB     . ALA   E 1 274 ? 285.142 240.200 212.991 1.00 38.18  ? 286 ALA   B CB     1 
ATOM   3096 N N      . SER   E 1 275 ? 284.351 243.297 213.868 1.00 40.84  ? 287 SER   B N      1 
ATOM   3097 C CA     . SER   E 1 275 ? 284.803 244.660 214.110 1.00 39.79  ? 287 SER   B CA     1 
ATOM   3098 C C      . SER   E 1 275 ? 284.369 245.197 215.466 1.00 43.92  ? 287 SER   B C      1 
ATOM   3099 O O      . SER   E 1 275 ? 284.510 246.399 215.709 1.00 42.87  ? 287 SER   B O      1 
ATOM   3100 C CB     . SER   E 1 275 ? 284.296 245.589 213.005 1.00 39.07  ? 287 SER   B CB     1 
ATOM   3101 O OG     . SER   E 1 275 ? 284.986 245.350 211.792 1.00 40.82  ? 287 SER   B OG     1 
ATOM   3102 N N      . GLY   E 1 276 ? 283.840 244.349 216.345 1.00 46.34  ? 288 GLY   B N      1 
ATOM   3103 C CA     . GLY   E 1 276 ? 283.375 244.776 217.647 1.00 46.23  ? 288 GLY   B CA     1 
ATOM   3104 C C      . GLY   E 1 276 ? 281.954 245.286 217.666 1.00 47.65  ? 288 GLY   B C      1 
ATOM   3105 O O      . GLY   E 1 276 ? 281.446 245.623 218.741 1.00 57.36  ? 288 GLY   B O      1 
ATOM   3106 N N      . TYR   E 1 277 ? 281.304 245.355 216.514 1.00 43.56  ? 289 TYR   B N      1 
ATOM   3107 C CA     . TYR   E 1 277 ? 279.957 245.890 216.431 1.00 44.11  ? 289 TYR   B CA     1 
ATOM   3108 C C      . TYR   E 1 277 ? 278.981 244.978 217.164 1.00 46.85  ? 289 TYR   B C      1 
ATOM   3109 O O      . TYR   E 1 277 ? 279.023 243.754 217.018 1.00 49.64  ? 289 TYR   B O      1 
ATOM   3110 C CB     . TYR   E 1 277 ? 279.575 246.041 214.963 1.00 43.29  ? 289 TYR   B CB     1 
ATOM   3111 C CG     . TYR   E 1 277 ? 278.295 246.775 214.706 1.00 44.90  ? 289 TYR   B CG     1 
ATOM   3112 C CD1    . TYR   E 1 277 ? 277.830 247.738 215.585 1.00 47.98  ? 289 TYR   B CD1    1 
ATOM   3113 C CD2    . TYR   E 1 277 ? 277.558 246.518 213.563 1.00 52.29  ? 289 TYR   B CD2    1 
ATOM   3114 C CE1    . TYR   E 1 277 ? 276.653 248.410 215.344 1.00 48.11  ? 289 TYR   B CE1    1 
ATOM   3115 C CE2    . TYR   E 1 277 ? 276.387 247.185 213.309 1.00 51.89  ? 289 TYR   B CE2    1 
ATOM   3116 C CZ     . TYR   E 1 277 ? 275.941 248.129 214.204 1.00 44.56  ? 289 TYR   B CZ     1 
ATOM   3117 O OH     . TYR   E 1 277 ? 274.767 248.799 213.953 1.00 43.61  ? 289 TYR   B OH     1 
ATOM   3118 N N      . ASP   E 1 278 ? 278.100 245.579 217.960 1.00 45.49  ? 290 ASP   B N      1 
ATOM   3119 C CA     . ASP   E 1 278 ? 277.156 244.844 218.800 1.00 46.73  ? 290 ASP   B CA     1 
ATOM   3120 C C      . ASP   E 1 278 ? 275.748 245.103 218.278 1.00 48.07  ? 290 ASP   B C      1 
ATOM   3121 O O      . ASP   E 1 278 ? 275.132 246.119 218.609 1.00 52.15  ? 290 ASP   B O      1 
ATOM   3122 C CB     . ASP   E 1 278 ? 277.279 245.261 220.262 1.00 49.96  ? 290 ASP   B CB     1 
ATOM   3123 C CG     . ASP   E 1 278 ? 276.922 244.142 221.221 1.00 52.53  ? 290 ASP   B CG     1 
ATOM   3124 O OD1    . ASP   E 1 278 ? 275.829 243.560 221.077 1.00 49.70  ? 290 ASP   B OD1    1 
ATOM   3125 O OD2    . ASP   E 1 278 ? 277.723 243.865 222.138 1.00 57.89  ? 290 ASP   B OD2    1 
ATOM   3126 N N      . PHE   E 1 279 ? 275.236 244.179 217.466 1.00 45.20  ? 291 PHE   B N      1 
ATOM   3127 C CA     . PHE   E 1 279 ? 273.880 244.336 216.957 1.00 44.75  ? 291 PHE   B CA     1 
ATOM   3128 C C      . PHE   E 1 279 ? 272.848 244.234 218.069 1.00 43.90  ? 291 PHE   B C      1 
ATOM   3129 O O      . PHE   E 1 279 ? 271.840 244.947 218.044 1.00 45.57  ? 291 PHE   B O      1 
ATOM   3130 C CB     . PHE   E 1 279 ? 273.601 243.294 215.880 1.00 45.73  ? 291 PHE   B CB     1 
ATOM   3131 C CG     . PHE   E 1 279 ? 274.390 243.502 214.628 1.00 42.01  ? 291 PHE   B CG     1 
ATOM   3132 C CD1    . PHE   E 1 279 ? 273.929 244.355 213.646 1.00 40.34  ? 291 PHE   B CD1    1 
ATOM   3133 C CD2    . PHE   E 1 279 ? 275.592 242.845 214.429 1.00 41.65  ? 291 PHE   B CD2    1 
ATOM   3134 C CE1    . PHE   E 1 279 ? 274.650 244.554 212.489 1.00 41.72  ? 291 PHE   B CE1    1 
ATOM   3135 C CE2    . PHE   E 1 279 ? 276.317 243.039 213.271 1.00 41.21  ? 291 PHE   B CE2    1 
ATOM   3136 C CZ     . PHE   E 1 279 ? 275.846 243.896 212.301 1.00 41.69  ? 291 PHE   B CZ     1 
ATOM   3137 N N      . GLU   E 1 280 ? 273.083 243.359 219.047 1.00 46.43  ? 292 GLU   B N      1 
ATOM   3138 C CA     . GLU   E 1 280 ? 272.126 243.183 220.133 1.00 48.84  ? 292 GLU   B CA     1 
ATOM   3139 C C      . GLU   E 1 280 ? 271.967 244.464 220.945 1.00 48.65  ? 292 GLU   B C      1 
ATOM   3140 O O      . GLU   E 1 280 ? 270.871 244.761 221.432 1.00 50.85  ? 292 GLU   B O      1 
ATOM   3141 C CB     . GLU   E 1 280 ? 272.563 242.022 221.027 1.00 47.91  ? 292 GLU   B CB     1 
ATOM   3142 C CG     . GLU   E 1 280 ? 271.943 241.997 222.414 1.00 47.59  ? 292 GLU   B CG     1 
ATOM   3143 C CD     . GLU   E 1 280 ? 270.605 241.303 222.430 1.00 51.35  ? 292 GLU   B CD     1 
ATOM   3144 O OE1    . GLU   E 1 280 ? 269.973 241.218 221.357 1.00 55.51  ? 292 GLU   B OE1    1 
ATOM   3145 O OE2    . GLU   E 1 280 ? 270.202 240.816 223.507 1.00 57.78  ? 292 GLU   B OE2    1 
ATOM   3146 N N      . ARG   E 1 281 ? 273.041 245.242 221.097 1.00 47.05  ? 293 ARG   B N      1 
ATOM   3147 C CA     . ARG   E 1 281 ? 272.978 246.431 221.942 1.00 48.87  ? 293 ARG   B CA     1 
ATOM   3148 C C      . ARG   E 1 281 ? 272.272 247.582 221.229 1.00 51.51  ? 293 ARG   B C      1 
ATOM   3149 O O      . ARG   E 1 281 ? 271.239 248.078 221.696 1.00 55.14  ? 293 ARG   B O      1 
ATOM   3150 C CB     . ARG   E 1 281 ? 274.389 246.827 222.394 1.00 54.01  ? 293 ARG   B CB     1 
ATOM   3151 C CG     . ARG   E 1 281 ? 274.517 248.275 222.817 1.00 60.39  ? 293 ARG   B CG     1 
ATOM   3152 C CD     . ARG   E 1 281 ? 275.904 248.824 222.534 1.00 66.18  ? 293 ARG   B CD     1 
ATOM   3153 N NE     . ARG   E 1 281 ? 276.938 248.090 223.253 1.00 70.58  ? 293 ARG   B NE     1 
ATOM   3154 C CZ     . ARG   E 1 281 ? 276.981 247.977 224.573 1.00 76.65  ? 293 ARG   B CZ     1 
ATOM   3155 N NH1    . ARG   E 1 281 ? 276.059 248.531 225.344 1.00 72.11  ? 293 ARG   B NH1    1 
ATOM   3156 N NH2    . ARG   E 1 281 ? 277.980 247.303 225.135 1.00 79.44  ? 293 ARG   B NH2    1 
ATOM   3157 N N      . GLU   E 1 282 ? 272.806 248.003 220.079 1.00 50.47  ? 294 GLU   B N      1 
ATOM   3158 C CA     . GLU   E 1 282 ? 272.229 249.109 219.322 1.00 49.97  ? 294 GLU   B CA     1 
ATOM   3159 C C      . GLU   E 1 282 ? 271.038 248.690 218.468 1.00 49.00  ? 294 GLU   B C      1 
ATOM   3160 O O      . GLU   E 1 282 ? 270.334 249.559 217.948 1.00 49.94  ? 294 GLU   B O      1 
ATOM   3161 C CB     . GLU   E 1 282 ? 273.304 249.739 218.441 1.00 48.88  ? 294 GLU   B CB     1 
ATOM   3162 C CG     . GLU   E 1 282 ? 274.122 250.841 219.071 1.00 63.26  ? 294 GLU   B CG     1 
ATOM   3163 C CD     . GLU   E 1 282 ? 275.399 251.111 218.282 1.00 76.44  ? 294 GLU   B CD     1 
ATOM   3164 O OE1    . GLU   E 1 282 ? 275.549 250.574 217.168 1.00 71.51  ? 294 GLU   B OE1    1 
ATOM   3165 O OE2    . GLU   E 1 282 ? 276.245 251.894 218.751 1.00 91.34  ? 294 GLU   B OE2    1 
ATOM   3166 N N      . GLY   E 1 283 ? 270.808 247.395 218.296 1.00 49.85  ? 295 GLY   B N      1 
ATOM   3167 C CA     . GLY   E 1 283 ? 269.628 246.925 217.605 1.00 46.69  ? 295 GLY   B CA     1 
ATOM   3168 C C      . GLY   E 1 283 ? 269.735 247.047 216.097 1.00 46.26  ? 295 GLY   B C      1 
ATOM   3169 O O      . GLY   E 1 283 ? 270.647 247.663 215.541 1.00 49.52  ? 295 GLY   B O      1 
ATOM   3170 N N      . TYR   E 1 284 ? 268.747 246.464 215.423 1.00 44.23  ? 296 TYR   B N      1 
ATOM   3171 C CA     . TYR   E 1 284 ? 268.784 246.318 213.980 1.00 41.92  ? 296 TYR   B CA     1 
ATOM   3172 C C      . TYR   E 1 284 ? 267.365 246.381 213.431 1.00 43.41  ? 296 TYR   B C      1 
ATOM   3173 O O      . TYR   E 1 284 ? 266.383 246.305 214.173 1.00 46.45  ? 296 TYR   B O      1 
ATOM   3174 C CB     . TYR   E 1 284 ? 269.467 245.005 213.599 1.00 42.39  ? 296 TYR   B CB     1 
ATOM   3175 C CG     . TYR   E 1 284 ? 270.051 245.006 212.220 1.00 40.27  ? 296 TYR   B CG     1 
ATOM   3176 C CD1    . TYR   E 1 284 ? 271.207 245.719 211.954 1.00 38.26  ? 296 TYR   B CD1    1 
ATOM   3177 C CD2    . TYR   E 1 284 ? 269.470 244.285 211.190 1.00 40.71  ? 296 TYR   B CD2    1 
ATOM   3178 C CE1    . TYR   E 1 284 ? 271.761 245.731 210.705 1.00 39.33  ? 296 TYR   B CE1    1 
ATOM   3179 C CE2    . TYR   E 1 284 ? 270.020 244.287 209.930 1.00 38.42  ? 296 TYR   B CE2    1 
ATOM   3180 C CZ     . TYR   E 1 284 ? 271.169 245.012 209.697 1.00 39.77  ? 296 TYR   B CZ     1 
ATOM   3181 O OH     . TYR   E 1 284 ? 271.732 245.027 208.447 1.00 44.78  ? 296 TYR   B OH     1 
ATOM   3182 N N      . SER   E 1 285 ? 267.266 246.522 212.111 1.00 43.95  ? 297 SER   B N      1 
ATOM   3183 C CA     . SER   E 1 285 ? 265.975 246.538 211.436 1.00 42.23  ? 297 SER   B CA     1 
ATOM   3184 C C      . SER   E 1 285 ? 266.153 246.202 209.962 1.00 42.81  ? 297 SER   B C      1 
ATOM   3185 O O      . SER   E 1 285 ? 267.037 246.751 209.297 1.00 42.42  ? 297 SER   B O      1 
ATOM   3186 C CB     . SER   E 1 285 ? 265.295 247.898 211.596 1.00 41.95  ? 297 SER   B CB     1 
ATOM   3187 O OG     . SER   E 1 285 ? 266.061 248.921 210.987 1.00 50.10  ? 297 SER   B OG     1 
ATOM   3188 N N      . LEU   E 1 286 ? 265.326 245.300 209.441 1.00 42.76  ? 298 LEU   B N      1 
ATOM   3189 C CA     . LEU   E 1 286 ? 265.465 244.865 208.059 1.00 41.44  ? 298 LEU   B CA     1 
ATOM   3190 C C      . LEU   E 1 286 ? 264.771 245.788 207.069 1.00 40.67  ? 298 LEU   B C      1 
ATOM   3191 O O      . LEU   E 1 286 ? 264.923 245.596 205.858 1.00 40.18  ? 298 LEU   B O      1 
ATOM   3192 C CB     . LEU   E 1 286 ? 264.927 243.442 207.907 1.00 41.59  ? 298 LEU   B CB     1 
ATOM   3193 C CG     . LEU   E 1 286 ? 265.501 242.423 208.889 1.00 38.62  ? 298 LEU   B CG     1 
ATOM   3194 C CD1    . LEU   E 1 286 ? 265.010 241.035 208.547 1.00 38.23  ? 298 LEU   B CD1    1 
ATOM   3195 C CD2    . LEU   E 1 286 ? 267.014 242.471 208.861 1.00 43.20  ? 298 LEU   B CD2    1 
ATOM   3196 N N      . VAL   E 1 287 ? 264.023 246.779 207.550 1.00 41.06  ? 299 VAL   B N      1 
ATOM   3197 C CA     . VAL   E 1 287 ? 263.301 247.713 206.699 1.00 40.32  ? 299 VAL   B CA     1 
ATOM   3198 C C      . VAL   E 1 287 ? 263.747 249.151 206.901 1.00 42.37  ? 299 VAL   B C      1 
ATOM   3199 O O      . VAL   E 1 287 ? 263.254 250.042 206.205 1.00 44.96  ? 299 VAL   B O      1 
ATOM   3200 C CB     . VAL   E 1 287 ? 261.779 247.597 206.913 1.00 38.77  ? 299 VAL   B CB     1 
ATOM   3201 C CG1    . VAL   E 1 287 ? 261.314 246.180 206.636 1.00 41.37  ? 299 VAL   B CG1    1 
ATOM   3202 C CG2    . VAL   E 1 287 ? 261.419 248.009 208.327 1.00 40.86  ? 299 VAL   B CG2    1 
ATOM   3203 N N      . GLY   E 1 288 ? 264.662 249.405 207.830 1.00 41.50  ? 300 GLY   B N      1 
ATOM   3204 C CA     . GLY   E 1 288 ? 265.111 250.741 208.141 1.00 38.88  ? 300 GLY   B CA     1 
ATOM   3205 C C      . GLY   E 1 288 ? 266.440 251.077 207.501 1.00 42.49  ? 300 GLY   B C      1 
ATOM   3206 O O      . GLY   E 1 288 ? 266.819 250.533 206.458 1.00 46.66  ? 300 GLY   B O      1 
ATOM   3207 N N      . ILE   E 1 289 ? 267.163 252.000 208.141 1.00 42.66  ? 301 ILE   B N      1 
ATOM   3208 C CA     . ILE   E 1 289 ? 268.467 252.429 207.640 1.00 40.41  ? 301 ILE   B CA     1 
ATOM   3209 C C      . ILE   E 1 289 ? 269.596 251.487 208.015 1.00 42.57  ? 301 ILE   B C      1 
ATOM   3210 O O      . ILE   E 1 289 ? 270.685 251.585 207.435 1.00 44.44  ? 301 ILE   B O      1 
ATOM   3211 C CB     . ILE   E 1 289 ? 268.827 253.834 208.156 1.00 41.32  ? 301 ILE   B CB     1 
ATOM   3212 C CG1    . ILE   E 1 289 ? 270.032 254.389 207.397 1.00 40.48  ? 301 ILE   B CG1    1 
ATOM   3213 C CG2    . ILE   E 1 289 ? 269.095 253.801 209.647 1.00 40.91  ? 301 ILE   B CG2    1 
ATOM   3214 C CD1    . ILE   E 1 289 ? 270.473 255.750 207.870 1.00 45.93  ? 301 ILE   B CD1    1 
ATOM   3215 N N      . ASP   E 1 290 ? 269.375 250.581 208.964 1.00 44.07  ? 302 ASP   B N      1 
ATOM   3216 C CA     . ASP   E 1 290 ? 270.470 249.740 209.442 1.00 39.52  ? 302 ASP   B CA     1 
ATOM   3217 C C      . ASP   E 1 290 ? 271.136 248.958 208.323 1.00 39.84  ? 302 ASP   B C      1 
ATOM   3218 O O      . ASP   E 1 290 ? 272.375 249.000 208.222 1.00 39.44  ? 302 ASP   B O      1 
ATOM   3219 C CB     . ASP   E 1 290 ? 269.955 248.805 210.539 1.00 39.52  ? 302 ASP   B CB     1 
ATOM   3220 C CG     . ASP   E 1 290 ? 269.367 249.556 211.710 1.00 41.79  ? 302 ASP   B CG     1 
ATOM   3221 O OD1    . ASP   E 1 290 ? 268.213 250.015 211.602 1.00 44.21  ? 302 ASP   B OD1    1 
ATOM   3222 O OD2    . ASP   E 1 290 ? 270.058 249.691 212.740 1.00 45.65  ? 302 ASP   B OD2    1 
ATOM   3223 N N      . PRO   E 1 291 ? 270.411 248.235 207.464 1.00 40.21  ? 303 PRO   B N      1 
ATOM   3224 C CA     . PRO   E 1 291 ? 271.092 247.519 206.373 1.00 39.35  ? 303 PRO   B CA     1 
ATOM   3225 C C      . PRO   E 1 291 ? 271.847 248.441 205.434 1.00 40.61  ? 303 PRO   B C      1 
ATOM   3226 O O      . PRO   E 1 291 ? 272.945 248.098 204.981 1.00 41.08  ? 303 PRO   B O      1 
ATOM   3227 C CB     . PRO   E 1 291 ? 269.941 246.793 205.659 1.00 38.29  ? 303 PRO   B CB     1 
ATOM   3228 C CG     . PRO   E 1 291 ? 268.821 246.774 206.643 1.00 39.17  ? 303 PRO   B CG     1 
ATOM   3229 C CD     . PRO   E 1 291 ? 268.955 248.029 207.433 1.00 41.93  ? 303 PRO   B CD     1 
ATOM   3230 N N      . PHE   E 1 292 ? 271.286 249.615 205.138 1.00 41.34  ? 304 PHE   B N      1 
ATOM   3231 C CA     . PHE   E 1 292 ? 271.952 250.552 204.241 1.00 41.49  ? 304 PHE   B CA     1 
ATOM   3232 C C      . PHE   E 1 292 ? 273.259 251.049 204.840 1.00 42.70  ? 304 PHE   B C      1 
ATOM   3233 O O      . PHE   E 1 292 ? 274.274 251.146 204.142 1.00 45.00  ? 304 PHE   B O      1 
ATOM   3234 C CB     . PHE   E 1 292 ? 271.021 251.724 203.935 1.00 43.24  ? 304 PHE   B CB     1 
ATOM   3235 C CG     . PHE   E 1 292 ? 270.185 251.527 202.707 1.00 40.61  ? 304 PHE   B CG     1 
ATOM   3236 C CD1    . PHE   E 1 292 ? 270.740 251.651 201.448 1.00 41.82  ? 304 PHE   B CD1    1 
ATOM   3237 C CD2    . PHE   E 1 292 ? 268.845 251.205 202.813 1.00 39.82  ? 304 PHE   B CD2    1 
ATOM   3238 C CE1    . PHE   E 1 292 ? 269.971 251.469 200.319 1.00 42.42  ? 304 PHE   B CE1    1 
ATOM   3239 C CE2    . PHE   E 1 292 ? 268.073 251.019 201.686 1.00 40.59  ? 304 PHE   B CE2    1 
ATOM   3240 C CZ     . PHE   E 1 292 ? 268.637 251.151 200.438 1.00 40.48  ? 304 PHE   B CZ     1 
ATOM   3241 N N      . ARG   E 1 293 ? 273.251 251.369 206.135 1.00 42.26  ? 305 ARG   B N      1 
ATOM   3242 C CA     . ARG   E 1 293 ? 274.463 251.834 206.797 1.00 42.55  ? 305 ARG   B CA     1 
ATOM   3243 C C      . ARG   E 1 293 ? 275.505 250.729 206.897 1.00 43.40  ? 305 ARG   B C      1 
ATOM   3244 O O      . ARG   E 1 293 ? 276.707 251.000 206.803 1.00 43.15  ? 305 ARG   B O      1 
ATOM   3245 C CB     . ARG   E 1 293 ? 274.113 252.378 208.180 1.00 43.12  ? 305 ARG   B CB     1 
ATOM   3246 C CG     . ARG   E 1 293 ? 275.296 252.777 209.030 1.00 42.52  ? 305 ARG   B CG     1 
ATOM   3247 C CD     . ARG   E 1 293 ? 274.820 253.288 210.375 1.00 42.69  ? 305 ARG   B CD     1 
ATOM   3248 N NE     . ARG   E 1 293 ? 274.057 252.278 211.097 1.00 42.03  ? 305 ARG   B NE     1 
ATOM   3249 C CZ     . ARG   E 1 293 ? 273.008 252.541 211.863 1.00 43.78  ? 305 ARG   B CZ     1 
ATOM   3250 N NH1    . ARG   E 1 293 ? 272.558 253.774 212.019 1.00 42.19  ? 305 ARG   B NH1    1 
ATOM   3251 N NH2    . ARG   E 1 293 ? 272.392 251.541 212.485 1.00 47.16  ? 305 ARG   B NH2    1 
ATOM   3252 N N      . LEU   E 1 294 ? 275.066 249.485 207.088 1.00 44.52  ? 306 LEU   B N      1 
ATOM   3253 C CA     . LEU   E 1 294 ? 276.004 248.370 207.146 1.00 42.77  ? 306 LEU   B CA     1 
ATOM   3254 C C      . LEU   E 1 294 ? 276.703 248.167 205.807 1.00 41.67  ? 306 LEU   B C      1 
ATOM   3255 O O      . LEU   E 1 294 ? 277.919 247.952 205.759 1.00 41.45  ? 306 LEU   B O      1 
ATOM   3256 C CB     . LEU   E 1 294 ? 275.271 247.099 207.571 1.00 40.10  ? 306 LEU   B CB     1 
ATOM   3257 C CG     . LEU   E 1 294 ? 276.127 245.925 208.039 1.00 40.51  ? 306 LEU   B CG     1 
ATOM   3258 C CD1    . LEU   E 1 294 ? 276.932 246.308 209.265 1.00 45.25  ? 306 LEU   B CD1    1 
ATOM   3259 C CD2    . LEU   E 1 294 ? 275.252 244.721 208.329 1.00 42.45  ? 306 LEU   B CD2    1 
ATOM   3260 N N      . LEU   E 1 295 ? 275.950 248.242 204.707 1.00 41.18  ? 307 LEU   B N      1 
ATOM   3261 C CA     . LEU   E 1 295 ? 276.528 247.998 203.390 1.00 42.70  ? 307 LEU   B CA     1 
ATOM   3262 C C      . LEU   E 1 295 ? 277.490 249.104 202.977 1.00 46.43  ? 307 LEU   B C      1 
ATOM   3263 O O      . LEU   E 1 295 ? 278.415 248.857 202.196 1.00 45.00  ? 307 LEU   B O      1 
ATOM   3264 C CB     . LEU   E 1 295 ? 275.417 247.844 202.352 1.00 40.94  ? 307 LEU   B CB     1 
ATOM   3265 C CG     . LEU   E 1 295 ? 274.863 246.431 202.163 1.00 38.28  ? 307 LEU   B CG     1 
ATOM   3266 C CD1    . LEU   E 1 295 ? 274.053 246.338 200.886 1.00 40.17  ? 307 LEU   B CD1    1 
ATOM   3267 C CD2    . LEU   E 1 295 ? 275.992 245.420 202.149 1.00 42.30  ? 307 LEU   B CD2    1 
ATOM   3268 N N      . GLN   E 1 296 ? 277.289 250.323 203.478 1.00 46.45  ? 308 GLN   B N      1 
ATOM   3269 C CA     . GLN   E 1 296 ? 278.188 251.418 203.129 1.00 44.71  ? 308 GLN   B CA     1 
ATOM   3270 C C      . GLN   E 1 296 ? 279.604 251.152 203.626 1.00 44.88  ? 308 GLN   B C      1 
ATOM   3271 O O      . GLN   E 1 296 ? 280.580 251.436 202.923 1.00 45.39  ? 308 GLN   B O      1 
ATOM   3272 C CB     . GLN   E 1 296 ? 277.658 252.731 203.701 1.00 43.03  ? 308 GLN   B CB     1 
ATOM   3273 C CG     . GLN   E 1 296 ? 277.994 253.949 202.868 1.00 40.20  ? 308 GLN   B CG     1 
ATOM   3274 C CD     . GLN   E 1 296 ? 276.918 254.275 201.860 1.00 42.11  ? 308 GLN   B CD     1 
ATOM   3275 O OE1    . GLN   E 1 296 ? 275.779 253.830 201.987 1.00 43.63  ? 308 GLN   B OE1    1 
ATOM   3276 N NE2    . GLN   E 1 296 ? 277.271 255.056 200.849 1.00 46.44  ? 308 GLN   B NE2    1 
ATOM   3277 N N      . ASN   E 1 297 ? 279.735 250.610 204.833 1.00 46.08  ? 309 ASN   B N      1 
ATOM   3278 C CA     . ASN   E 1 297 ? 281.031 250.370 205.449 1.00 45.35  ? 309 ASN   B CA     1 
ATOM   3279 C C      . ASN   E 1 297 ? 281.580 248.981 205.153 1.00 45.53  ? 309 ASN   B C      1 
ATOM   3280 O O      . ASN   E 1 297 ? 282.697 248.665 205.574 1.00 47.34  ? 309 ASN   B O      1 
ATOM   3281 C CB     . ASN   E 1 297 ? 280.934 250.572 206.962 1.00 45.57  ? 309 ASN   B CB     1 
ATOM   3282 C CG     . ASN   E 1 297 ? 280.346 251.915 207.333 1.00 51.93  ? 309 ASN   B CG     1 
ATOM   3283 O OD1    . ASN   E 1 297 ? 279.992 252.711 206.465 1.00 57.77  ? 309 ASN   B OD1    1 
ATOM   3284 N ND2    . ASN   E 1 297 ? 280.231 252.172 208.629 1.00 54.13  ? 309 ASN   B ND2    1 
ATOM   3285 N N      . SER   E 1 298 ? 280.835 248.152 204.430 1.00 42.74  ? 310 SER   B N      1 
ATOM   3286 C CA     . SER   E 1 298 ? 281.176 246.751 204.242 1.00 44.08  ? 310 SER   B CA     1 
ATOM   3287 C C      . SER   E 1 298 ? 281.764 246.528 202.857 1.00 43.35  ? 310 SER   B C      1 
ATOM   3288 O O      . SER   E 1 298 ? 281.218 247.002 201.856 1.00 45.57  ? 310 SER   B O      1 
ATOM   3289 C CB     . SER   E 1 298 ? 279.945 245.862 204.429 1.00 47.06  ? 310 SER   B CB     1 
ATOM   3290 O OG     . SER   E 1 298 ? 279.186 245.802 203.236 1.00 51.49  ? 310 SER   B OG     1 
ATOM   3291 N N      . GLN   E 1 299 ? 282.876 245.799 202.808 1.00 41.82  ? 311 GLN   B N      1 
ATOM   3292 C CA     . GLN   E 1 299 ? 283.548 245.461 201.562 1.00 46.07  ? 311 GLN   B CA     1 
ATOM   3293 C C      . GLN   E 1 299 ? 283.427 243.964 201.327 1.00 46.20  ? 311 GLN   B C      1 
ATOM   3294 O O      . GLN   E 1 299 ? 283.773 243.165 202.202 1.00 47.59  ? 311 GLN   B O      1 
ATOM   3295 C CB     . GLN   E 1 299 ? 285.019 245.880 201.594 1.00 44.31  ? 311 GLN   B CB     1 
ATOM   3296 C CG     . GLN   E 1 299 ? 285.847 245.153 202.631 1.00 46.49  ? 311 GLN   B CG     1 
ATOM   3297 C CD     . GLN   E 1 299 ? 287.280 245.634 202.665 1.00 52.06  ? 311 GLN   B CD     1 
ATOM   3298 O OE1    . GLN   E 1 299 ? 287.592 246.721 202.182 1.00 51.74  ? 311 GLN   B OE1    1 
ATOM   3299 N NE2    . GLN   E 1 299 ? 288.162 244.826 203.238 1.00 59.46  ? 311 GLN   B NE2    1 
ATOM   3300 N N      . VAL   E 1 300 ? 282.936 243.590 200.150 1.00 44.43  ? 312 VAL   B N      1 
ATOM   3301 C CA     . VAL   E 1 300 ? 282.665 242.197 199.821 1.00 43.58  ? 312 VAL   B CA     1 
ATOM   3302 C C      . VAL   E 1 300 ? 283.243 241.896 198.447 1.00 45.30  ? 312 VAL   B C      1 
ATOM   3303 O O      . VAL   E 1 300 ? 283.066 242.672 197.502 1.00 51.59  ? 312 VAL   B O      1 
ATOM   3304 C CB     . VAL   E 1 300 ? 281.153 241.892 199.855 1.00 44.92  ? 312 VAL   B CB     1 
ATOM   3305 C CG1    . VAL   E 1 300 ? 280.854 240.620 199.086 1.00 45.57  ? 312 VAL   B CG1    1 
ATOM   3306 C CG2    . VAL   E 1 300 ? 280.667 241.786 201.287 1.00 46.82  ? 312 VAL   B CG2    1 
ATOM   3307 N N      . TYR   E 1 301 ? 283.935 240.768 198.339 1.00 43.14  ? 313 TYR   B N      1 
ATOM   3308 C CA     . TYR   E 1 301 ? 284.530 240.320 197.091 1.00 43.21  ? 313 TYR   B CA     1 
ATOM   3309 C C      . TYR   E 1 301 ? 283.714 239.177 196.504 1.00 42.80  ? 313 TYR   B C      1 
ATOM   3310 O O      . TYR   E 1 301 ? 282.989 238.478 197.216 1.00 42.94  ? 313 TYR   B O      1 
ATOM   3311 C CB     . TYR   E 1 301 ? 285.979 239.872 197.301 1.00 44.76  ? 313 TYR   B CB     1 
ATOM   3312 C CG     . TYR   E 1 301 ? 286.788 240.814 198.157 1.00 46.28  ? 313 TYR   B CG     1 
ATOM   3313 C CD1    . TYR   E 1 301 ? 287.366 241.951 197.616 1.00 48.51  ? 313 TYR   B CD1    1 
ATOM   3314 C CD2    . TYR   E 1 301 ? 286.965 240.572 199.510 1.00 50.20  ? 313 TYR   B CD2    1 
ATOM   3315 C CE1    . TYR   E 1 301 ? 288.104 242.817 198.397 1.00 48.70  ? 313 TYR   B CE1    1 
ATOM   3316 C CE2    . TYR   E 1 301 ? 287.699 241.433 200.298 1.00 48.57  ? 313 TYR   B CE2    1 
ATOM   3317 C CZ     . TYR   E 1 301 ? 288.266 242.552 199.737 1.00 46.79  ? 313 TYR   B CZ     1 
ATOM   3318 O OH     . TYR   E 1 301 ? 288.999 243.410 200.521 1.00 49.19  ? 313 TYR   B OH     1 
ATOM   3319 N N      . SER   E 1 302 ? 283.831 239.002 195.192 1.00 45.08  ? 314 SER   B N      1 
ATOM   3320 C CA     . SER   E 1 302 ? 283.117 237.955 194.482 1.00 42.79  ? 314 SER   B CA     1 
ATOM   3321 C C      . SER   E 1 302 ? 283.990 237.416 193.361 1.00 42.35  ? 314 SER   B C      1 
ATOM   3322 O O      . SER   E 1 302 ? 284.967 238.050 192.954 1.00 42.76  ? 314 SER   B O      1 
ATOM   3323 C CB     . SER   E 1 302 ? 281.789 238.461 193.910 1.00 44.85  ? 314 SER   B CB     1 
ATOM   3324 O OG     . SER   E 1 302 ? 281.346 237.630 192.852 1.00 47.67  ? 314 SER   B OG     1 
ATOM   3325 N N      . LEU   E 1 303 ? 283.639 236.229 192.880 1.00 45.60  ? 315 LEU   B N      1 
ATOM   3326 C CA     . LEU   E 1 303 ? 284.318 235.644 191.734 1.00 45.57  ? 315 LEU   B CA     1 
ATOM   3327 C C      . LEU   E 1 303 ? 283.666 236.134 190.449 1.00 46.84  ? 315 LEU   B C      1 
ATOM   3328 O O      . LEU   E 1 303 ? 282.449 236.017 190.276 1.00 47.02  ? 315 LEU   B O      1 
ATOM   3329 C CB     . LEU   E 1 303 ? 284.277 234.120 191.804 1.00 41.24  ? 315 LEU   B CB     1 
ATOM   3330 C CG     . LEU   E 1 303 ? 285.126 233.485 192.903 1.00 38.06  ? 315 LEU   B CG     1 
ATOM   3331 C CD1    . LEU   E 1 303 ? 284.992 231.977 192.874 1.00 41.87  ? 315 LEU   B CD1    1 
ATOM   3332 C CD2    . LEU   E 1 303 ? 286.577 233.899 192.755 1.00 46.91  ? 315 LEU   B CD2    1 
ATOM   3333 N N      . ILE   E 1 304 ? 284.475 236.681 189.549 1.00 47.68  ? 316 ILE   B N      1 
ATOM   3334 C CA     . ILE   E 1 304 ? 284.000 237.228 188.286 1.00 44.67  ? 316 ILE   B CA     1 
ATOM   3335 C C      . ILE   E 1 304 ? 284.482 236.315 187.168 1.00 45.35  ? 316 ILE   B C      1 
ATOM   3336 O O      . ILE   E 1 304 ? 285.689 236.093 187.014 1.00 48.73  ? 316 ILE   B O      1 
ATOM   3337 C CB     . ILE   E 1 304 ? 284.488 238.668 188.073 1.00 44.13  ? 316 ILE   B CB     1 
ATOM   3338 C CG1    . ILE   E 1 304 ? 283.579 239.648 188.813 1.00 41.62  ? 316 ILE   B CG1    1 
ATOM   3339 C CG2    . ILE   E 1 304 ? 284.526 239.000 186.594 1.00 46.59  ? 316 ILE   B CG2    1 
ATOM   3340 C CD1    . ILE   E 1 304 ? 282.242 239.851 188.149 1.00 42.98  ? 316 ILE   B CD1    1 
ATOM   3341 N N      . ARG   E 1 305 ? 283.542 235.782 186.396 1.00 44.02  ? 317 ARG   B N      1 
ATOM   3342 C CA     . ARG   E 1 305 ? 283.888 234.920 185.284 1.00 44.77  ? 317 ARG   B CA     1 
ATOM   3343 C C      . ARG   E 1 305 ? 284.491 235.741 184.149 1.00 48.90  ? 317 ARG   B C      1 
ATOM   3344 O O      . ARG   E 1 305 ? 284.262 236.948 184.052 1.00 52.22  ? 317 ARG   B O      1 
ATOM   3345 C CB     . ARG   E 1 305 ? 282.656 234.165 184.800 1.00 43.55  ? 317 ARG   B CB     1 
ATOM   3346 C CG     . ARG   E 1 305 ? 281.704 233.803 185.920 1.00 46.48  ? 317 ARG   B CG     1 
ATOM   3347 C CD     . ARG   E 1 305 ? 280.792 232.656 185.543 1.00 43.30  ? 317 ARG   B CD     1 
ATOM   3348 N NE     . ARG   E 1 305 ? 279.492 232.790 186.187 1.00 43.59  ? 317 ARG   B NE     1 
ATOM   3349 C CZ     . ARG   E 1 305 ? 278.913 231.841 186.910 1.00 40.22  ? 317 ARG   B CZ     1 
ATOM   3350 N NH1    . ARG   E 1 305 ? 279.480 230.659 187.079 1.00 45.12  ? 317 ARG   B NH1    1 
ATOM   3351 N NH2    . ARG   E 1 305 ? 277.734 232.083 187.473 1.00 41.47  ? 317 ARG   B NH2    1 
ATOM   3352 N N      . PRO   E 1 306 ? 285.273 235.107 183.279 1.00 48.14  ? 318 PRO   B N      1 
ATOM   3353 C CA     . PRO   E 1 306 ? 285.882 235.849 182.171 1.00 48.90  ? 318 PRO   B CA     1 
ATOM   3354 C C      . PRO   E 1 306 ? 284.820 236.520 181.314 1.00 51.85  ? 318 PRO   B C      1 
ATOM   3355 O O      . PRO   E 1 306 ? 283.757 235.954 181.051 1.00 55.48  ? 318 PRO   B O      1 
ATOM   3356 C CB     . PRO   E 1 306 ? 286.638 234.767 181.390 1.00 49.92  ? 318 PRO   B CB     1 
ATOM   3357 C CG     . PRO   E 1 306 ? 286.046 233.470 181.842 1.00 47.51  ? 318 PRO   B CG     1 
ATOM   3358 C CD     . PRO   E 1 306 ? 285.633 233.682 183.258 1.00 49.17  ? 318 PRO   B CD     1 
ATOM   3359 N N      . ASN   E 1 307 ? 285.121 237.741 180.874 1.00 48.54  ? 319 ASN   B N      1 
ATOM   3360 C CA     . ASN   E 1 307 ? 284.208 238.531 180.052 1.00 50.68  ? 319 ASN   B CA     1 
ATOM   3361 C C      . ASN   E 1 307 ? 282.885 238.771 180.786 1.00 48.34  ? 319 ASN   B C      1 
ATOM   3362 O O      . ASN   E 1 307 ? 281.801 238.404 180.331 1.00 53.25  ? 319 ASN   B O      1 
ATOM   3363 C CB     . ASN   E 1 307 ? 283.974 237.852 178.698 1.00 51.92  ? 319 ASN   B CB     1 
ATOM   3364 C CG     . ASN   E 1 307 ? 285.141 238.025 177.753 1.00 60.73  ? 319 ASN   B CG     1 
ATOM   3365 O OD1    . ASN   E 1 307 ? 286.278 238.218 178.181 1.00 66.73  ? 319 ASN   B OD1    1 
ATOM   3366 N ND2    . ASN   E 1 307 ? 284.868 237.954 176.456 1.00 66.76  ? 319 ASN   B ND2    1 
ATOM   3367 N N      . GLU   E 1 308 ? 283.012 239.411 181.944 1.00 44.29  ? 320 GLU   B N      1 
ATOM   3368 C CA     . GLU   E 1 308 ? 281.860 239.783 182.752 1.00 43.62  ? 320 GLU   B CA     1 
ATOM   3369 C C      . GLU   E 1 308 ? 282.134 241.140 183.376 1.00 45.41  ? 320 GLU   B C      1 
ATOM   3370 O O      . GLU   E 1 308 ? 283.236 241.389 183.871 1.00 47.57  ? 320 GLU   B O      1 
ATOM   3371 C CB     . GLU   E 1 308 ? 281.575 238.741 183.841 1.00 43.55  ? 320 GLU   B CB     1 
ATOM   3372 C CG     . GLU   E 1 308 ? 280.563 237.684 183.442 1.00 41.92  ? 320 GLU   B CG     1 
ATOM   3373 C CD     . GLU   E 1 308 ? 279.925 237.004 184.637 1.00 41.89  ? 320 GLU   B CD     1 
ATOM   3374 O OE1    . GLU   E 1 308 ? 280.342 237.282 185.778 1.00 43.24  ? 320 GLU   B OE1    1 
ATOM   3375 O OE2    . GLU   E 1 308 ? 279.006 236.185 184.433 1.00 41.99  ? 320 GLU   B OE2    1 
ATOM   3376 N N      . ASN   E 1 309 ? 281.131 242.013 183.351 1.00 43.99  ? 321 ASN   B N      1 
ATOM   3377 C CA     . ASN   E 1 309 ? 281.280 243.350 183.906 1.00 43.91  ? 321 ASN   B CA     1 
ATOM   3378 C C      . ASN   E 1 309 ? 281.144 243.290 185.420 1.00 44.00  ? 321 ASN   B C      1 
ATOM   3379 O O      . ASN   E 1 309 ? 280.076 242.910 185.918 1.00 45.16  ? 321 ASN   B O      1 
ATOM   3380 C CB     . ASN   E 1 309 ? 280.240 244.294 183.326 1.00 40.29  ? 321 ASN   B CB     1 
ATOM   3381 C CG     . ASN   E 1 309 ? 280.655 245.750 183.423 1.00 38.80  ? 321 ASN   B CG     1 
ATOM   3382 O OD1    . ASN   E 1 309 ? 281.691 246.074 184.000 1.00 41.38  ? 321 ASN   B OD1    1 
ATOM   3383 N ND2    . ASN   E 1 309 ? 279.842 246.635 182.864 1.00 38.27  ? 321 ASN   B ND2    1 
ATOM   3384 N N      . PRO   E 1 310 ? 282.177 243.653 186.183 1.00 43.04  ? 322 PRO   B N      1 
ATOM   3385 C CA     . PRO   E 1 310 ? 282.049 243.599 187.647 1.00 43.09  ? 322 PRO   B CA     1 
ATOM   3386 C C      . PRO   E 1 310 ? 280.937 244.477 188.182 1.00 41.03  ? 322 PRO   B C      1 
ATOM   3387 O O      . PRO   E 1 310 ? 280.304 244.118 189.182 1.00 41.39  ? 322 PRO   B O      1 
ATOM   3388 C CB     . PRO   E 1 310 ? 283.428 244.064 188.136 1.00 42.05  ? 322 PRO   B CB     1 
ATOM   3389 C CG     . PRO   E 1 310 ? 284.005 244.827 186.997 1.00 39.19  ? 322 PRO   B CG     1 
ATOM   3390 C CD     . PRO   E 1 310 ? 283.489 244.166 185.758 1.00 41.77  ? 322 PRO   B CD     1 
ATOM   3391 N N      . ALA   E 1 311 ? 280.675 245.619 187.544 1.00 41.22  ? 323 ALA   B N      1 
ATOM   3392 C CA     . ALA   E 1 311 ? 279.615 246.505 188.016 1.00 39.34  ? 323 ALA   B CA     1 
ATOM   3393 C C      . ALA   E 1 311 ? 278.247 245.847 187.897 1.00 39.21  ? 323 ALA   B C      1 
ATOM   3394 O O      . ALA   E 1 311 ? 277.397 246.001 188.781 1.00 42.63  ? 323 ALA   B O      1 
ATOM   3395 C CB     . ALA   E 1 311 ? 279.648 247.821 187.242 1.00 37.10  ? 323 ALA   B CB     1 
ATOM   3396 N N      . HIS   E 1 312 ? 278.008 245.120 186.804 1.00 38.86  ? 324 HIS   B N      1 
ATOM   3397 C CA     . HIS   E 1 312 ? 276.708 244.486 186.615 1.00 40.11  ? 324 HIS   B CA     1 
ATOM   3398 C C      . HIS   E 1 312 ? 276.460 243.403 187.658 1.00 40.70  ? 324 HIS   B C      1 
ATOM   3399 O O      . HIS   E 1 312 ? 275.337 243.257 188.152 1.00 41.47  ? 324 HIS   B O      1 
ATOM   3400 C CB     . HIS   E 1 312 ? 276.601 243.919 185.201 1.00 39.26  ? 324 HIS   B CB     1 
ATOM   3401 C CG     . HIS   E 1 312 ? 276.449 244.967 184.144 1.00 40.89  ? 324 HIS   B CG     1 
ATOM   3402 N ND1    . HIS   E 1 312 ? 276.896 244.794 182.853 1.00 43.05  ? 324 HIS   B ND1    1 
ATOM   3403 C CD2    . HIS   E 1 312 ? 275.905 246.206 184.190 1.00 42.66  ? 324 HIS   B CD2    1 
ATOM   3404 C CE1    . HIS   E 1 312 ? 276.631 245.879 182.148 1.00 43.53  ? 324 HIS   B CE1    1 
ATOM   3405 N NE2    . HIS   E 1 312 ? 276.029 246.751 182.936 1.00 41.04  ? 324 HIS   B NE2    1 
ATOM   3406 N N      . LYS   E 1 313 ? 277.490 242.628 188.000 1.00 40.23  ? 325 LYS   B N      1 
ATOM   3407 C CA     . LYS   E 1 313 ? 277.338 241.655 189.076 1.00 39.63  ? 325 LYS   B CA     1 
ATOM   3408 C C      . LYS   E 1 313 ? 277.108 242.351 190.412 1.00 38.86  ? 325 LYS   B C      1 
ATOM   3409 O O      . LYS   E 1 313 ? 276.294 241.898 191.223 1.00 39.61  ? 325 LYS   B O      1 
ATOM   3410 C CB     . LYS   E 1 313 ? 278.563 240.744 189.145 1.00 37.12  ? 325 LYS   B CB     1 
ATOM   3411 C CG     . LYS   E 1 313 ? 278.356 239.508 190.005 1.00 39.01  ? 325 LYS   B CG     1 
ATOM   3412 C CD     . LYS   E 1 313 ? 279.557 238.581 189.951 1.00 38.98  ? 325 LYS   B CD     1 
ATOM   3413 C CE     . LYS   E 1 313 ? 279.455 237.596 188.802 1.00 33.89  ? 325 LYS   B CE     1 
ATOM   3414 N NZ     . LYS   E 1 313 ? 278.112 236.975 188.724 1.00 39.24  ? 325 LYS   B NZ     1 
ATOM   3415 N N      . SER   E 1 314 ? 277.812 243.459 190.655 1.00 39.44  ? 326 SER   B N      1 
ATOM   3416 C CA     . SER   E 1 314 ? 277.610 244.205 191.891 1.00 40.34  ? 326 SER   B CA     1 
ATOM   3417 C C      . SER   E 1 314 ? 276.197 244.768 191.969 1.00 39.31  ? 326 SER   B C      1 
ATOM   3418 O O      . SER   E 1 314 ? 275.584 244.783 193.042 1.00 41.51  ? 326 SER   B O      1 
ATOM   3419 C CB     . SER   E 1 314 ? 278.646 245.323 192.004 1.00 39.92  ? 326 SER   B CB     1 
ATOM   3420 O OG     . SER   E 1 314 ? 278.540 246.225 190.919 1.00 44.88  ? 326 SER   B OG     1 
ATOM   3421 N N      . GLN   E 1 315 ? 275.665 245.244 190.842 1.00 37.52  ? 327 GLN   B N      1 
ATOM   3422 C CA     . GLN   E 1 315 ? 274.288 245.725 190.832 1.00 40.12  ? 327 GLN   B CA     1 
ATOM   3423 C C      . GLN   E 1 315 ? 273.314 244.587 191.102 1.00 40.14  ? 327 GLN   B C      1 
ATOM   3424 O O      . GLN   E 1 315 ? 272.296 244.776 191.779 1.00 43.03  ? 327 GLN   B O      1 
ATOM   3425 C CB     . GLN   E 1 315 ? 273.973 246.400 189.497 1.00 39.51  ? 327 GLN   B CB     1 
ATOM   3426 C CG     . GLN   E 1 315 ? 272.498 246.684 189.286 1.00 38.91  ? 327 GLN   B CG     1 
ATOM   3427 C CD     . GLN   E 1 315 ? 272.093 246.634 187.831 1.00 39.17  ? 327 GLN   B CD     1 
ATOM   3428 O OE1    . GLN   E 1 315 ? 272.749 247.223 186.974 1.00 43.57  ? 327 GLN   B OE1    1 
ATOM   3429 N NE2    . GLN   E 1 315 ? 271.001 245.939 187.543 1.00 34.94  ? 327 GLN   B NE2    1 
ATOM   3430 N N      . LEU   E 1 316 ? 273.608 243.398 190.578 1.00 38.66  ? 328 LEU   B N      1 
ATOM   3431 C CA     . LEU   E 1 316 ? 272.762 242.242 190.844 1.00 37.05  ? 328 LEU   B CA     1 
ATOM   3432 C C      . LEU   E 1 316 ? 272.760 241.894 192.327 1.00 37.13  ? 328 LEU   B C      1 
ATOM   3433 O O      . LEU   E 1 316 ? 271.708 241.594 192.902 1.00 37.22  ? 328 LEU   B O      1 
ATOM   3434 C CB     . LEU   E 1 316 ? 273.232 241.055 190.004 1.00 36.41  ? 328 LEU   B CB     1 
ATOM   3435 C CG     . LEU   E 1 316 ? 272.397 239.778 190.035 1.00 38.52  ? 328 LEU   B CG     1 
ATOM   3436 C CD1    . LEU   E 1 316 ? 271.250 239.884 189.050 1.00 38.30  ? 328 LEU   B CD1    1 
ATOM   3437 C CD2    . LEU   E 1 316 ? 273.267 238.581 189.711 1.00 41.67  ? 328 LEU   B CD2    1 
ATOM   3438 N N      . VAL   E 1 317 ? 273.930 241.932 192.965 1.00 38.62  ? 329 VAL   B N      1 
ATOM   3439 C CA     . VAL   E 1 317 ? 273.993 241.664 194.397 1.00 37.64  ? 329 VAL   B CA     1 
ATOM   3440 C C      . VAL   E 1 317 ? 273.324 242.787 195.178 1.00 38.62  ? 329 VAL   B C      1 
ATOM   3441 O O      . VAL   E 1 317 ? 272.659 242.545 196.191 1.00 42.03  ? 329 VAL   B O      1 
ATOM   3442 C CB     . VAL   E 1 317 ? 275.449 241.448 194.839 1.00 38.87  ? 329 VAL   B CB     1 
ATOM   3443 C CG1    . VAL   E 1 317 ? 275.533 241.360 196.351 1.00 40.46  ? 329 VAL   B CG1    1 
ATOM   3444 C CG2    . VAL   E 1 317 ? 276.008 240.191 194.201 1.00 39.71  ? 329 VAL   B CG2    1 
ATOM   3445 N N      . TRP   E 1 318 ? 273.490 244.030 194.725 1.00 37.91  ? 330 TRP   B N      1 
ATOM   3446 C CA     . TRP   E 1 318 ? 272.807 245.146 195.370 1.00 38.25  ? 330 TRP   B CA     1 
ATOM   3447 C C      . TRP   E 1 318 ? 271.295 244.985 195.271 1.00 38.69  ? 330 TRP   B C      1 
ATOM   3448 O O      . TRP   E 1 318 ? 270.566 245.222 196.240 1.00 38.85  ? 330 TRP   B O      1 
ATOM   3449 C CB     . TRP   E 1 318 ? 273.255 246.468 194.746 1.00 36.70  ? 330 TRP   B CB     1 
ATOM   3450 C CG     . TRP   E 1 318 ? 272.645 247.661 195.399 1.00 37.73  ? 330 TRP   B CG     1 
ATOM   3451 C CD1    . TRP   E 1 318 ? 273.152 248.369 196.444 1.00 40.19  ? 330 TRP   B CD1    1 
ATOM   3452 C CD2    . TRP   E 1 318 ? 271.402 248.281 195.059 1.00 38.53  ? 330 TRP   B CD2    1 
ATOM   3453 N NE1    . TRP   E 1 318 ? 272.305 249.396 196.777 1.00 39.88  ? 330 TRP   B NE1    1 
ATOM   3454 C CE2    . TRP   E 1 318 ? 271.222 249.364 195.940 1.00 38.03  ? 330 TRP   B CE2    1 
ATOM   3455 C CE3    . TRP   E 1 318 ? 270.424 248.028 194.094 1.00 37.99  ? 330 TRP   B CE3    1 
ATOM   3456 C CZ2    . TRP   E 1 318 ? 270.106 250.190 195.886 1.00 38.28  ? 330 TRP   B CZ2    1 
ATOM   3457 C CZ3    . TRP   E 1 318 ? 269.318 248.849 194.042 1.00 35.97  ? 330 TRP   B CZ3    1 
ATOM   3458 C CH2    . TRP   E 1 318 ? 269.167 249.917 194.932 1.00 40.21  ? 330 TRP   B CH2    1 
ATOM   3459 N N      . MET   E 1 319 ? 270.808 244.573 194.100 1.00 38.09  ? 331 MET   B N      1 
ATOM   3460 C CA     . MET   E 1 319 ? 269.377 244.360 193.916 1.00 39.09  ? 331 MET   B CA     1 
ATOM   3461 C C      . MET   E 1 319 ? 268.861 243.254 194.829 1.00 40.67  ? 331 MET   B C      1 
ATOM   3462 O O      . MET   E 1 319 ? 267.779 243.375 195.415 1.00 41.04  ? 331 MET   B O      1 
ATOM   3463 C CB     . MET   E 1 319 ? 269.098 244.025 192.452 1.00 40.11  ? 331 MET   B CB     1 
ATOM   3464 C CG     . MET   E 1 319 ? 269.140 245.227 191.530 1.00 40.17  ? 331 MET   B CG     1 
ATOM   3465 S SD     . MET   E 1 319 ? 268.278 244.960 189.974 1.00 52.92  ? 331 MET   B SD     1 
ATOM   3466 C CE     . MET   E 1 319 ? 266.579 244.970 190.520 1.00 46.92  ? 331 MET   B CE     1 
ATOM   3467 N N      . ALA   E 1 320 ? 269.619 242.164 194.954 1.00 39.22  ? 332 ALA   B N      1 
ATOM   3468 C CA     . ALA   E 1 320 ? 269.198 241.057 195.806 1.00 38.75  ? 332 ALA   B CA     1 
ATOM   3469 C C      . ALA   E 1 320 ? 269.218 241.449 197.277 1.00 39.61  ? 332 ALA   B C      1 
ATOM   3470 O O      . ALA   E 1 320 ? 268.362 241.012 198.054 1.00 41.03  ? 332 ALA   B O      1 
ATOM   3471 C CB     . ALA   E 1 320 ? 270.090 239.842 195.564 1.00 37.54  ? 332 ALA   B CB     1 
ATOM   3472 N N      . CYS   E 1 321 ? 270.192 242.266 197.679 1.00 38.71  ? 333 CYS   B N      1 
ATOM   3473 C CA     . CYS   E 1 321 ? 270.321 242.628 199.086 1.00 38.72  ? 333 CYS   B CA     1 
ATOM   3474 C C      . CYS   E 1 321 ? 269.081 243.357 199.584 1.00 40.82  ? 333 CYS   B C      1 
ATOM   3475 O O      . CYS   E 1 321 ? 268.614 243.112 200.702 1.00 43.77  ? 333 CYS   B O      1 
ATOM   3476 C CB     . CYS   E 1 321 ? 271.568 243.486 199.292 1.00 37.73  ? 333 CYS   B CB     1 
ATOM   3477 S SG     . CYS   E 1 321 ? 273.109 242.552 199.374 1.00 48.82  ? 333 CYS   B SG     1 
ATOM   3478 N N      . HIS   E 1 322 ? 268.534 244.257 198.770 1.00 40.45  ? 334 HIS   B N      1 
ATOM   3479 C CA     . HIS   E 1 322 ? 267.388 245.066 199.154 1.00 38.86  ? 334 HIS   B CA     1 
ATOM   3480 C C      . HIS   E 1 322 ? 266.078 244.554 198.565 1.00 40.09  ? 334 HIS   B C      1 
ATOM   3481 O O      . HIS   E 1 322 ? 265.046 245.213 198.711 1.00 40.33  ? 334 HIS   B O      1 
ATOM   3482 C CB     . HIS   E 1 322 ? 267.619 246.521 198.746 1.00 37.30  ? 334 HIS   B CB     1 
ATOM   3483 C CG     . HIS   E 1 322 ? 268.778 247.163 199.444 1.00 40.64  ? 334 HIS   B CG     1 
ATOM   3484 N ND1    . HIS   E 1 322 ? 269.968 247.440 198.808 1.00 41.76  ? 334 HIS   B ND1    1 
ATOM   3485 C CD2    . HIS   E 1 322 ? 268.934 247.565 200.727 1.00 41.18  ? 334 HIS   B CD2    1 
ATOM   3486 C CE1    . HIS   E 1 322 ? 270.804 247.996 199.666 1.00 38.63  ? 334 HIS   B CE1    1 
ATOM   3487 N NE2    . HIS   E 1 322 ? 270.202 248.082 200.838 1.00 39.96  ? 334 HIS   B NE2    1 
ATOM   3488 N N      . SER   E 1 323 ? 266.099 243.390 197.914 1.00 42.37  ? 335 SER   B N      1 
ATOM   3489 C CA     . SER   E 1 323 ? 264.894 242.767 197.363 1.00 42.26  ? 335 SER   B CA     1 
ATOM   3490 C C      . SER   E 1 323 ? 264.161 243.708 196.409 1.00 41.97  ? 335 SER   B C      1 
ATOM   3491 O O      . SER   E 1 323 ? 262.934 243.813 196.432 1.00 45.88  ? 335 SER   B O      1 
ATOM   3492 C CB     . SER   E 1 323 ? 263.963 242.289 198.479 1.00 41.04  ? 335 SER   B CB     1 
ATOM   3493 O OG     . SER   E 1 323 ? 263.327 243.378 199.120 1.00 43.84  ? 335 SER   B OG     1 
ATOM   3494 N N      . ALA   E 1 324 ? 264.921 244.392 195.555 1.00 40.28  ? 336 ALA   B N      1 
ATOM   3495 C CA     . ALA   E 1 324 ? 264.362 245.324 194.585 1.00 40.50  ? 336 ALA   B CA     1 
ATOM   3496 C C      . ALA   E 1 324 ? 264.344 244.752 193.173 1.00 40.59  ? 336 ALA   B C      1 
ATOM   3497 O O      . ALA   E 1 324 ? 264.457 245.502 192.200 1.00 45.66  ? 336 ALA   B O      1 
ATOM   3498 C CB     . ALA   E 1 324 ? 265.136 246.641 194.609 1.00 40.18  ? 336 ALA   B CB     1 
ATOM   3499 N N      . ALA   E 1 325 ? 264.196 243.433 193.041 1.00 37.09  ? 337 ALA   B N      1 
ATOM   3500 C CA     . ALA   E 1 325 ? 264.220 242.814 191.720 1.00 38.05  ? 337 ALA   B CA     1 
ATOM   3501 C C      . ALA   E 1 325 ? 263.035 243.261 190.874 1.00 42.52  ? 337 ALA   B C      1 
ATOM   3502 O O      . ALA   E 1 325 ? 263.178 243.506 189.671 1.00 45.87  ? 337 ALA   B O      1 
ATOM   3503 C CB     . ALA   E 1 325 ? 264.239 241.292 191.856 1.00 40.81  ? 337 ALA   B CB     1 
ATOM   3504 N N      . PHE   E 1 326 ? 261.857 243.370 191.482 1.00 43.34  ? 338 PHE   B N      1 
ATOM   3505 C CA     . PHE   E 1 326 ? 260.637 243.737 190.776 1.00 40.15  ? 338 PHE   B CA     1 
ATOM   3506 C C      . PHE   E 1 326 ? 260.243 245.189 190.999 1.00 42.10  ? 338 PHE   B C      1 
ATOM   3507 O O      . PHE   E 1 326 ? 259.110 245.568 190.691 1.00 50.06  ? 338 PHE   B O      1 
ATOM   3508 C CB     . PHE   E 1 326 ? 259.496 242.811 191.194 1.00 41.73  ? 338 PHE   B CB     1 
ATOM   3509 C CG     . PHE   E 1 326 ? 259.839 241.356 191.099 1.00 41.64  ? 338 PHE   B CG     1 
ATOM   3510 C CD1    . PHE   E 1 326 ? 260.122 240.779 189.876 1.00 42.17  ? 338 PHE   B CD1    1 
ATOM   3511 C CD2    . PHE   E 1 326 ? 259.888 240.567 192.232 1.00 41.36  ? 338 PHE   B CD2    1 
ATOM   3512 C CE1    . PHE   E 1 326 ? 260.442 239.442 189.784 1.00 41.45  ? 338 PHE   B CE1    1 
ATOM   3513 C CE2    . PHE   E 1 326 ? 260.204 239.229 192.145 1.00 43.64  ? 338 PHE   B CE2    1 
ATOM   3514 C CZ     . PHE   E 1 326 ? 260.483 238.666 190.920 1.00 44.15  ? 338 PHE   B CZ     1 
ATOM   3515 N N      . GLU   E 1 327 ? 261.147 246.005 191.527 1.00 40.33  ? 339 GLU   B N      1 
ATOM   3516 C CA     . GLU   E 1 327 ? 260.858 247.404 191.783 1.00 41.46  ? 339 GLU   B CA     1 
ATOM   3517 C C      . GLU   E 1 327 ? 261.216 248.250 190.564 1.00 42.00  ? 339 GLU   B C      1 
ATOM   3518 O O      . GLU   E 1 327 ? 261.972 247.833 189.683 1.00 47.26  ? 339 GLU   B O      1 
ATOM   3519 C CB     . GLU   E 1 327 ? 261.617 247.882 193.020 1.00 41.65  ? 339 GLU   B CB     1 
ATOM   3520 C CG     . GLU   E 1 327 ? 261.756 249.384 193.155 1.00 41.62  ? 339 GLU   B CG     1 
ATOM   3521 C CD     . GLU   E 1 327 ? 260.506 250.027 193.707 1.00 44.93  ? 339 GLU   B CD     1 
ATOM   3522 O OE1    . GLU   E 1 327 ? 259.422 249.430 193.560 1.00 51.96  ? 339 GLU   B OE1    1 
ATOM   3523 O OE2    . GLU   E 1 327 ? 260.603 251.124 194.290 1.00 45.48  ? 339 GLU   B OE2    1 
ATOM   3524 N N      . ASP   E 1 328 ? 260.649 249.453 190.519 1.00 39.57  ? 340 ASP   B N      1 
ATOM   3525 C CA     . ASP   E 1 328 ? 260.868 250.345 189.389 1.00 40.22  ? 340 ASP   B CA     1 
ATOM   3526 C C      . ASP   E 1 328 ? 262.354 250.619 189.198 1.00 41.59  ? 340 ASP   B C      1 
ATOM   3527 O O      . ASP   E 1 328 ? 263.088 250.867 190.158 1.00 41.64  ? 340 ASP   B O      1 
ATOM   3528 C CB     . ASP   E 1 328 ? 260.110 251.654 189.608 1.00 39.45  ? 340 ASP   B CB     1 
ATOM   3529 C CG     . ASP   E 1 328 ? 260.034 252.498 188.360 1.00 44.46  ? 340 ASP   B CG     1 
ATOM   3530 O OD1    . ASP   E 1 328 ? 260.691 252.143 187.361 1.00 51.92  ? 340 ASP   B OD1    1 
ATOM   3531 O OD2    . ASP   E 1 328 ? 259.309 253.512 188.373 1.00 45.34  ? 340 ASP   B OD2    1 
ATOM   3532 N N      . LEU   E 1 329 ? 262.798 250.569 187.942 1.00 41.23  ? 341 LEU   B N      1 
ATOM   3533 C CA     . LEU   E 1 329 ? 264.195 250.862 187.647 1.00 41.20  ? 341 LEU   B CA     1 
ATOM   3534 C C      . LEU   E 1 329 ? 264.548 252.306 187.978 1.00 41.72  ? 341 LEU   B C      1 
ATOM   3535 O O      . LEU   E 1 329 ? 265.652 252.577 188.462 1.00 43.36  ? 341 LEU   B O      1 
ATOM   3536 C CB     . LEU   E 1 329 ? 264.496 250.563 186.179 1.00 42.16  ? 341 LEU   B CB     1 
ATOM   3537 C CG     . LEU   E 1 329 ? 265.040 249.172 185.854 1.00 37.71  ? 341 LEU   B CG     1 
ATOM   3538 C CD1    . LEU   E 1 329 ? 266.491 249.058 186.271 1.00 39.92  ? 341 LEU   B CD1    1 
ATOM   3539 C CD2    . LEU   E 1 329 ? 264.209 248.102 186.534 1.00 41.04  ? 341 LEU   B CD2    1 
ATOM   3540 N N      . ARG   E 1 330 ? 263.631 253.241 187.723 1.00 41.32  ? 342 ARG   B N      1 
ATOM   3541 C CA     . ARG   E 1 330 ? 263.913 254.649 187.983 1.00 41.56  ? 342 ARG   B CA     1 
ATOM   3542 C C      . ARG   E 1 330 ? 264.145 254.899 189.468 1.00 41.06  ? 342 ARG   B C      1 
ATOM   3543 O O      . ARG   E 1 330 ? 265.058 255.640 189.847 1.00 40.55  ? 342 ARG   B O      1 
ATOM   3544 C CB     . ARG   E 1 330 ? 262.766 255.517 187.465 1.00 40.99  ? 342 ARG   B CB     1 
ATOM   3545 C CG     . ARG   E 1 330 ? 262.236 255.107 186.106 1.00 41.39  ? 342 ARG   B CG     1 
ATOM   3546 C CD     . ARG   E 1 330 ? 261.076 255.990 185.686 1.00 40.85  ? 342 ARG   B CD     1 
ATOM   3547 N NE     . ARG   E 1 330 ? 259.789 255.385 186.004 1.00 40.68  ? 342 ARG   B NE     1 
ATOM   3548 C CZ     . ARG   E 1 330 ? 258.764 256.040 186.532 1.00 42.55  ? 342 ARG   B CZ     1 
ATOM   3549 N NH1    . ARG   E 1 330 ? 258.837 257.330 186.809 1.00 43.13  ? 342 ARG   B NH1    1 
ATOM   3550 N NH2    . ARG   E 1 330 ? 257.637 255.383 186.788 1.00 44.03  ? 342 ARG   B NH2    1 
ATOM   3551 N N      . VAL   E 1 331 ? 263.321 254.295 190.325 1.00 39.11  ? 343 VAL   B N      1 
ATOM   3552 C CA     . VAL   E 1 331 ? 263.497 254.477 191.762 1.00 39.93  ? 343 VAL   B CA     1 
ATOM   3553 C C      . VAL   E 1 331 ? 264.769 253.784 192.235 1.00 39.39  ? 343 VAL   B C      1 
ATOM   3554 O O      . VAL   E 1 331 ? 265.503 254.312 193.078 1.00 39.29  ? 343 VAL   B O      1 
ATOM   3555 C CB     . VAL   E 1 331 ? 262.255 253.980 192.522 1.00 38.16  ? 343 VAL   B CB     1 
ATOM   3556 C CG1    . VAL   E 1 331 ? 261.911 252.569 192.102 1.00 44.46  ? 343 VAL   B CG1    1 
ATOM   3557 C CG2    . VAL   E 1 331 ? 262.490 254.044 194.018 1.00 38.03  ? 343 VAL   B CG2    1 
ATOM   3558 N N      . SER   E 1 332 ? 265.050 252.592 191.706 1.00 39.48  ? 344 SER   B N      1 
ATOM   3559 C CA     . SER   E 1 332 ? 266.285 251.902 192.061 1.00 39.95  ? 344 SER   B CA     1 
ATOM   3560 C C      . SER   E 1 332 ? 267.507 252.678 191.587 1.00 39.43  ? 344 SER   B C      1 
ATOM   3561 O O      . SER   E 1 332 ? 268.504 252.784 192.309 1.00 42.11  ? 344 SER   B O      1 
ATOM   3562 C CB     . SER   E 1 332 ? 266.283 250.491 191.475 1.00 42.23  ? 344 SER   B CB     1 
ATOM   3563 O OG     . SER   E 1 332 ? 265.367 249.659 192.161 1.00 45.77  ? 344 SER   B OG     1 
ATOM   3564 N N      . SER   E 1 333 ? 267.449 253.227 190.373 1.00 39.81  ? 345 SER   B N      1 
ATOM   3565 C CA     . SER   E 1 333 ? 268.567 254.017 189.868 1.00 39.67  ? 345 SER   B CA     1 
ATOM   3566 C C      . SER   E 1 333 ? 268.795 255.257 190.722 1.00 40.43  ? 345 SER   B C      1 
ATOM   3567 O O      . SER   E 1 333 ? 269.942 255.628 190.997 1.00 44.01  ? 345 SER   B O      1 
ATOM   3568 C CB     . SER   E 1 333 ? 268.318 254.406 188.412 1.00 38.32  ? 345 SER   B CB     1 
ATOM   3569 O OG     . SER   E 1 333 ? 268.209 253.259 187.591 1.00 41.12  ? 345 SER   B OG     1 
ATOM   3570 N N      . PHE   E 1 334 ? 267.714 255.910 191.150 1.00 37.88  ? 346 PHE   B N      1 
ATOM   3571 C CA     . PHE   E 1 334 ? 267.843 257.104 191.977 1.00 37.87  ? 346 PHE   B CA     1 
ATOM   3572 C C      . PHE   E 1 334 ? 268.522 256.792 193.305 1.00 41.64  ? 346 PHE   B C      1 
ATOM   3573 O O      . PHE   E 1 334 ? 269.407 257.533 193.747 1.00 46.77  ? 346 PHE   B O      1 
ATOM   3574 C CB     . PHE   E 1 334 ? 266.462 257.715 192.211 1.00 40.24  ? 346 PHE   B CB     1 
ATOM   3575 C CG     . PHE   E 1 334 ? 266.496 259.149 192.641 1.00 40.54  ? 346 PHE   B CG     1 
ATOM   3576 C CD1    . PHE   E 1 334 ? 265.985 259.530 193.868 1.00 43.46  ? 346 PHE   B CD1    1 
ATOM   3577 C CD2    . PHE   E 1 334 ? 267.032 260.119 191.816 1.00 40.93  ? 346 PHE   B CD2    1 
ATOM   3578 C CE1    . PHE   E 1 334 ? 266.011 260.849 194.264 1.00 44.00  ? 346 PHE   B CE1    1 
ATOM   3579 C CE2    . PHE   E 1 334 ? 267.061 261.440 192.209 1.00 44.10  ? 346 PHE   B CE2    1 
ATOM   3580 C CZ     . PHE   E 1 334 ? 266.550 261.804 193.434 1.00 43.60  ? 346 PHE   B CZ     1 
ATOM   3581 N N      . ILE   E 1 335 ? 268.121 255.700 193.957 1.00 41.82  ? 347 ILE   B N      1 
ATOM   3582 C CA     . ILE   E 1 335 ? 268.664 255.381 195.274 1.00 42.31  ? 347 ILE   B CA     1 
ATOM   3583 C C      . ILE   E 1 335 ? 270.119 254.944 195.168 1.00 40.07  ? 347 ILE   B C      1 
ATOM   3584 O O      . ILE   E 1 335 ? 270.959 255.331 195.988 1.00 40.83  ? 347 ILE   B O      1 
ATOM   3585 C CB     . ILE   E 1 335 ? 267.796 254.312 195.960 1.00 39.13  ? 347 ILE   B CB     1 
ATOM   3586 C CG1    . ILE   E 1 335 ? 266.410 254.876 196.270 1.00 38.16  ? 347 ILE   B CG1    1 
ATOM   3587 C CG2    . ILE   E 1 335 ? 268.463 253.817 197.227 1.00 42.63  ? 347 ILE   B CG2    1 
ATOM   3588 C CD1    . ILE   E 1 335 ? 265.457 253.863 196.845 1.00 42.74  ? 347 ILE   B CD1    1 
ATOM   3589 N N      . ARG   E 1 336 ? 270.440 254.124 194.168 1.00 38.71  ? 348 ARG   B N      1 
ATOM   3590 C CA     . ARG   E 1 336 ? 271.811 253.651 194.016 1.00 40.12  ? 348 ARG   B CA     1 
ATOM   3591 C C      . ARG   E 1 336 ? 272.747 254.781 193.604 1.00 42.03  ? 348 ARG   B C      1 
ATOM   3592 O O      . ARG   E 1 336 ? 273.914 254.808 194.012 1.00 43.17  ? 348 ARG   B O      1 
ATOM   3593 C CB     . ARG   E 1 336 ? 271.861 252.513 192.999 1.00 38.52  ? 348 ARG   B CB     1 
ATOM   3594 C CG     . ARG   E 1 336 ? 273.234 251.904 192.825 1.00 39.56  ? 348 ARG   B CG     1 
ATOM   3595 C CD     . ARG   E 1 336 ? 273.154 250.581 192.095 1.00 40.30  ? 348 ARG   B CD     1 
ATOM   3596 N NE     . ARG   E 1 336 ? 274.474 250.076 191.744 1.00 39.65  ? 348 ARG   B NE     1 
ATOM   3597 C CZ     . ARG   E 1 336 ? 275.350 249.607 192.621 1.00 43.18  ? 348 ARG   B CZ     1 
ATOM   3598 N NH1    . ARG   E 1 336 ? 275.083 249.582 193.916 1.00 46.87  ? 348 ARG   B NH1    1 
ATOM   3599 N NH2    . ARG   E 1 336 ? 276.522 249.155 192.189 1.00 44.09  ? 348 ARG   B NH2    1 
ATOM   3600 N N      . GLY   E 1 337 ? 272.259 255.717 192.797 1.00 41.68  ? 349 GLY   B N      1 
ATOM   3601 C CA     . GLY   E 1 337 ? 273.061 256.798 192.280 1.00 42.08  ? 349 GLY   B CA     1 
ATOM   3602 C C      . GLY   E 1 337 ? 273.685 256.515 190.932 1.00 47.82  ? 349 GLY   B C      1 
ATOM   3603 O O      . GLY   E 1 337 ? 274.089 257.456 190.240 1.00 58.07  ? 349 GLY   B O      1 
ATOM   3604 N N      . THR   E 1 338 ? 273.771 255.247 190.545 1.00 43.60  ? 350 THR   B N      1 
ATOM   3605 C CA     . THR   E 1 338 ? 274.229 254.842 189.226 1.00 42.29  ? 350 THR   B CA     1 
ATOM   3606 C C      . THR   E 1 338 ? 273.110 254.072 188.544 1.00 43.38  ? 350 THR   B C      1 
ATOM   3607 O O      . THR   E 1 338 ? 272.346 253.359 189.201 1.00 45.44  ? 350 THR   B O      1 
ATOM   3608 C CB     . THR   E 1 338 ? 275.492 253.980 189.305 1.00 41.90  ? 350 THR   B CB     1 
ATOM   3609 O OG1    . THR   E 1 338 ? 275.125 252.610 189.509 1.00 47.56  ? 350 THR   B OG1    1 
ATOM   3610 C CG2    . THR   E 1 338 ? 276.375 254.436 190.451 1.00 42.91  ? 350 THR   B CG2    1 
ATOM   3611 N N      . LYS   E 1 339 ? 273.008 254.229 187.230 1.00 44.13  ? 351 LYS   B N      1 
ATOM   3612 C CA     . LYS   E 1 339 ? 271.878 253.670 186.503 1.00 42.43  ? 351 LYS   B CA     1 
ATOM   3613 C C      . LYS   E 1 339 ? 271.788 252.166 186.718 1.00 41.97  ? 351 LYS   B C      1 
ATOM   3614 O O      . LYS   E 1 339 ? 272.790 251.450 186.644 1.00 41.53  ? 351 LYS   B O      1 
ATOM   3615 C CB     . LYS   E 1 339 ? 272.003 253.988 185.014 1.00 41.27  ? 351 LYS   B CB     1 
ATOM   3616 C CG     . LYS   E 1 339 ? 270.678 253.988 184.274 1.00 45.14  ? 351 LYS   B CG     1 
ATOM   3617 C CD     . LYS   E 1 339 ? 270.836 254.441 182.832 1.00 47.94  ? 351 LYS   B CD     1 
ATOM   3618 C CE     . LYS   E 1 339 ? 272.129 253.936 182.213 1.00 54.56  ? 351 LYS   B CE     1 
ATOM   3619 N NZ     . LYS   E 1 339 ? 272.411 252.512 182.552 1.00 58.84  ? 351 LYS   B NZ     1 
ATOM   3620 N N      . VAL   E 1 340 ? 270.581 251.693 187.000 1.00 40.41  ? 352 VAL   B N      1 
ATOM   3621 C CA     . VAL   E 1 340 ? 270.303 250.267 187.105 1.00 37.79  ? 352 VAL   B CA     1 
ATOM   3622 C C      . VAL   E 1 340 ? 269.836 249.768 185.745 1.00 38.42  ? 352 VAL   B C      1 
ATOM   3623 O O      . VAL   E 1 340 ? 268.933 250.352 185.134 1.00 38.90  ? 352 VAL   B O      1 
ATOM   3624 C CB     . VAL   E 1 340 ? 269.253 249.990 188.193 1.00 37.20  ? 352 VAL   B CB     1 
ATOM   3625 C CG1    . VAL   E 1 340 ? 269.019 248.500 188.336 1.00 39.19  ? 352 VAL   B CG1    1 
ATOM   3626 C CG2    . VAL   E 1 340 ? 269.698 250.585 189.514 1.00 38.63  ? 352 VAL   B CG2    1 
ATOM   3627 N N      . VAL   E 1 341 ? 270.456 248.697 185.264 1.00 39.33  ? 353 VAL   B N      1 
ATOM   3628 C CA     . VAL   E 1 341 ? 270.175 248.177 183.930 1.00 37.96  ? 353 VAL   B CA     1 
ATOM   3629 C C      . VAL   E 1 341 ? 269.164 247.040 184.024 1.00 41.69  ? 353 VAL   B C      1 
ATOM   3630 O O      . VAL   E 1 341 ? 269.133 246.321 185.032 1.00 44.61  ? 353 VAL   B O      1 
ATOM   3631 C CB     . VAL   E 1 341 ? 271.465 247.710 183.239 1.00 36.96  ? 353 VAL   B CB     1 
ATOM   3632 C CG1    . VAL   E 1 341 ? 271.280 247.682 181.735 1.00 40.29  ? 353 VAL   B CG1    1 
ATOM   3633 C CG2    . VAL   E 1 341 ? 272.620 248.617 183.619 1.00 40.33  ? 353 VAL   B CG2    1 
ATOM   3634 N N      . PRO   E 1 342 ? 268.321 246.845 183.015 1.00 40.57  ? 354 PRO   B N      1 
ATOM   3635 C CA     . PRO   E 1 342 ? 267.431 245.680 183.010 1.00 39.65  ? 354 PRO   B CA     1 
ATOM   3636 C C      . PRO   E 1 342 ? 268.226 244.384 182.951 1.00 40.99  ? 354 PRO   B C      1 
ATOM   3637 O O      . PRO   E 1 342 ? 269.424 244.360 182.665 1.00 42.52  ? 354 PRO   B O      1 
ATOM   3638 C CB     . PRO   E 1 342 ? 266.579 245.879 181.752 1.00 38.64  ? 354 PRO   B CB     1 
ATOM   3639 C CG     . PRO   E 1 342 ? 267.326 246.868 180.923 1.00 36.92  ? 354 PRO   B CG     1 
ATOM   3640 C CD     . PRO   E 1 342 ? 268.061 247.745 181.881 1.00 39.54  ? 354 PRO   B CD     1 
ATOM   3641 N N      . ARG   E 1 343 ? 267.531 243.284 183.239 1.00 41.49  ? 355 ARG   B N      1 
ATOM   3642 C CA     . ARG   E 1 343 ? 268.192 241.983 183.271 1.00 39.54  ? 355 ARG   B CA     1 
ATOM   3643 C C      . ARG   E 1 343 ? 268.755 241.613 181.905 1.00 38.50  ? 355 ARG   B C      1 
ATOM   3644 O O      . ARG   E 1 343 ? 269.831 241.013 181.811 1.00 40.75  ? 355 ARG   B O      1 
ATOM   3645 C CB     . ARG   E 1 343 ? 267.220 240.912 183.760 1.00 37.46  ? 355 ARG   B CB     1 
ATOM   3646 C CG     . ARG   E 1 343 ? 267.817 239.518 183.832 1.00 34.73  ? 355 ARG   B CG     1 
ATOM   3647 C CD     . ARG   E 1 343 ? 268.914 239.422 184.872 1.00 34.59  ? 355 ARG   B CD     1 
ATOM   3648 N NE     . ARG   E 1 343 ? 269.394 238.054 185.021 1.00 35.68  ? 355 ARG   B NE     1 
ATOM   3649 C CZ     . ARG   E 1 343 ? 270.521 237.595 184.496 1.00 34.04  ? 355 ARG   B CZ     1 
ATOM   3650 N NH1    . ARG   E 1 343 ? 271.314 238.370 183.777 1.00 35.01  ? 355 ARG   B NH1    1 
ATOM   3651 N NH2    . ARG   E 1 343 ? 270.859 236.325 184.696 1.00 32.37  ? 355 ARG   B NH2    1 
ATOM   3652 N N      . GLY   E 1 344 ? 268.039 241.955 180.834 1.00 37.70  ? 356 GLY   B N      1 
ATOM   3653 C CA     . GLY   E 1 344 ? 268.500 241.594 179.506 1.00 38.86  ? 356 GLY   B CA     1 
ATOM   3654 C C      . GLY   E 1 344 ? 269.812 242.248 179.127 1.00 40.00  ? 356 GLY   B C      1 
ATOM   3655 O O      . GLY   E 1 344 ? 270.539 241.738 178.271 1.00 42.72  ? 356 GLY   B O      1 
ATOM   3656 N N      . LYS   E 1 345 ? 270.136 243.378 179.751 1.00 38.73  ? 357 LYS   B N      1 
ATOM   3657 C CA     . LYS   E 1 345 ? 271.358 244.109 179.452 1.00 37.43  ? 357 LYS   B CA     1 
ATOM   3658 C C      . LYS   E 1 345 ? 272.435 243.908 180.509 1.00 39.52  ? 357 LYS   B C      1 
ATOM   3659 O O      . LYS   E 1 345 ? 273.426 244.643 180.517 1.00 41.04  ? 357 LYS   B O      1 
ATOM   3660 C CB     . LYS   E 1 345 ? 271.053 245.598 179.284 1.00 36.04  ? 357 LYS   B CB     1 
ATOM   3661 C CG     . LYS   E 1 345 ? 269.997 245.882 178.235 1.00 36.53  ? 357 LYS   B CG     1 
ATOM   3662 C CD     . LYS   E 1 345 ? 270.211 247.230 177.579 1.00 38.95  ? 357 LYS   B CD     1 
ATOM   3663 C CE     . LYS   E 1 345 ? 269.815 247.187 176.117 1.00 38.85  ? 357 LYS   B CE     1 
ATOM   3664 N NZ     . LYS   E 1 345 ? 270.162 245.881 175.499 1.00 40.17  ? 357 LYS   B NZ     1 
ATOM   3665 N N      . LEU   E 1 346 ? 272.261 242.936 181.397 1.00 41.27  ? 358 LEU   B N      1 
ATOM   3666 C CA     . LEU   E 1 346 ? 273.279 242.584 182.376 1.00 40.92  ? 358 LEU   B CA     1 
ATOM   3667 C C      . LEU   E 1 346 ? 274.224 241.569 181.747 1.00 42.62  ? 358 LEU   B C      1 
ATOM   3668 O O      . LEU   E 1 346 ? 273.793 240.488 181.333 1.00 45.17  ? 358 LEU   B O      1 
ATOM   3669 C CB     . LEU   E 1 346 ? 272.640 242.016 183.642 1.00 38.58  ? 358 LEU   B CB     1 
ATOM   3670 C CG     . LEU   E 1 346 ? 272.247 243.017 184.728 1.00 39.69  ? 358 LEU   B CG     1 
ATOM   3671 C CD1    . LEU   E 1 346 ? 272.063 242.314 186.058 1.00 39.17  ? 358 LEU   B CD1    1 
ATOM   3672 C CD2    . LEU   E 1 346 ? 273.282 244.118 184.842 1.00 42.84  ? 358 LEU   B CD2    1 
ATOM   3673 N N      . SER   E 1 347 ? 275.505 241.916 181.670 1.00 42.07  ? 359 SER   B N      1 
ATOM   3674 C CA     . SER   E 1 347 ? 276.500 241.038 181.056 1.00 40.52  ? 359 SER   B CA     1 
ATOM   3675 C C      . SER   E 1 347 ? 277.155 240.151 182.116 1.00 44.04  ? 359 SER   B C      1 
ATOM   3676 O O      . SER   E 1 347 ? 278.366 240.164 182.326 1.00 51.32  ? 359 SER   B O      1 
ATOM   3677 C CB     . SER   E 1 347 ? 277.536 241.864 180.304 1.00 42.84  ? 359 SER   B CB     1 
ATOM   3678 O OG     . SER   E 1 347 ? 278.328 242.620 181.201 1.00 52.24  ? 359 SER   B OG     1 
ATOM   3679 N N      . THR   E 1 348 ? 276.319 239.368 182.792 1.00 42.04  ? 360 THR   B N      1 
ATOM   3680 C CA     . THR   E 1 348 ? 276.798 238.510 183.864 1.00 41.34  ? 360 THR   B CA     1 
ATOM   3681 C C      . THR   E 1 348 ? 275.846 237.337 184.038 1.00 41.51  ? 360 THR   B C      1 
ATOM   3682 O O      . THR   E 1 348 ? 274.651 237.441 183.754 1.00 46.13  ? 360 THR   B O      1 
ATOM   3683 C CB     . THR   E 1 348 ? 276.928 239.280 185.182 1.00 40.03  ? 360 THR   B CB     1 
ATOM   3684 O OG1    . THR   E 1 348 ? 277.231 238.365 186.242 1.00 45.80  ? 360 THR   B OG1    1 
ATOM   3685 C CG2    . THR   E 1 348 ? 275.633 239.998 185.504 1.00 40.42  ? 360 THR   B CG2    1 
ATOM   3686 N N      . ARG   E 1 349 ? 276.394 236.222 184.501 1.00 38.96  ? 361 ARG   B N      1 
ATOM   3687 C CA     . ARG   E 1 349 ? 275.618 235.058 184.889 1.00 38.20  ? 361 ARG   B CA     1 
ATOM   3688 C C      . ARG   E 1 349 ? 275.421 235.067 186.405 1.00 39.31  ? 361 ARG   B C      1 
ATOM   3689 O O      . ARG   E 1 349 ? 275.724 236.049 187.089 1.00 43.20  ? 361 ARG   B O      1 
ATOM   3690 C CB     . ARG   E 1 349 ? 276.302 233.783 184.392 1.00 39.59  ? 361 ARG   B CB     1 
ATOM   3691 C CG     . ARG   E 1 349 ? 276.054 233.498 182.923 1.00 36.84  ? 361 ARG   B CG     1 
ATOM   3692 C CD     . ARG   E 1 349 ? 277.044 232.490 182.367 1.00 38.15  ? 361 ARG   B CD     1 
ATOM   3693 N NE     . ARG   E 1 349 ? 277.276 231.373 183.273 1.00 38.62  ? 361 ARG   B NE     1 
ATOM   3694 C CZ     . ARG   E 1 349 ? 276.527 230.280 183.322 1.00 41.83  ? 361 ARG   B CZ     1 
ATOM   3695 N NH1    . ARG   E 1 349 ? 275.477 230.126 182.533 1.00 45.81  ? 361 ARG   B NH1    1 
ATOM   3696 N NH2    . ARG   E 1 349 ? 276.843 229.316 184.181 1.00 42.74  ? 361 ARG   B NH2    1 
ATOM   3697 N N      . GLY   E 1 350 ? 274.907 233.966 186.944 1.00 39.50  ? 362 GLY   B N      1 
ATOM   3698 C CA     . GLY   E 1 350 ? 274.599 233.916 188.359 1.00 39.71  ? 362 GLY   B CA     1 
ATOM   3699 C C      . GLY   E 1 350 ? 275.836 234.025 189.230 1.00 38.84  ? 362 GLY   B C      1 
ATOM   3700 O O      . GLY   E 1 350 ? 276.965 233.780 188.806 1.00 42.11  ? 362 GLY   B O      1 
ATOM   3701 N N      . VAL   E 1 351 ? 275.601 234.411 190.486 1.00 38.90  ? 363 VAL   B N      1 
ATOM   3702 C CA     . VAL   E 1 351 ? 276.695 234.565 191.440 1.00 40.57  ? 363 VAL   B CA     1 
ATOM   3703 C C      . VAL   E 1 351 ? 277.347 233.222 191.740 1.00 40.54  ? 363 VAL   B C      1 
ATOM   3704 O O      . VAL   E 1 351 ? 278.577 233.113 191.802 1.00 44.09  ? 363 VAL   B O      1 
ATOM   3705 C CB     . VAL   E 1 351 ? 276.186 235.245 192.724 1.00 38.37  ? 363 VAL   B CB     1 
ATOM   3706 C CG1    . VAL   E 1 351 ? 277.177 235.047 193.852 1.00 36.40  ? 363 VAL   B CG1    1 
ATOM   3707 C CG2    . VAL   E 1 351 ? 275.948 236.723 192.479 1.00 39.77  ? 363 VAL   B CG2    1 
ATOM   3708 N N      . GLN   E 1 352 ? 276.541 232.183 191.934 1.00 40.83  ? 364 GLN   B N      1 
ATOM   3709 C CA     . GLN   E 1 352 ? 277.073 230.887 192.327 1.00 40.30  ? 364 GLN   B CA     1 
ATOM   3710 C C      . GLN   E 1 352 ? 277.803 230.232 191.161 1.00 40.83  ? 364 GLN   B C      1 
ATOM   3711 O O      . GLN   E 1 352 ? 277.297 230.185 190.037 1.00 42.83  ? 364 GLN   B O      1 
ATOM   3712 C CB     . GLN   E 1 352 ? 275.941 229.990 192.821 1.00 41.99  ? 364 GLN   B CB     1 
ATOM   3713 C CG     . GLN   E 1 352 ? 276.268 229.205 194.072 1.00 43.22  ? 364 GLN   B CG     1 
ATOM   3714 C CD     . GLN   E 1 352 ? 275.043 228.940 194.918 1.00 46.22  ? 364 GLN   B CD     1 
ATOM   3715 O OE1    . GLN   E 1 352 ? 273.923 229.255 194.521 1.00 43.47  ? 364 GLN   B OE1    1 
ATOM   3716 N NE2    . GLN   E 1 352 ? 275.249 228.356 196.091 1.00 47.44  ? 364 GLN   B NE2    1 
ATOM   3717 N N      . ILE   E 1 353 ? 278.996 229.716 191.437 1.00 39.99  ? 365 ILE   B N      1 
ATOM   3718 C CA     . ILE   E 1 353 ? 279.858 229.129 190.417 1.00 42.13  ? 365 ILE   B CA     1 
ATOM   3719 C C      . ILE   E 1 353 ? 279.570 227.640 190.325 1.00 42.54  ? 365 ILE   B C      1 
ATOM   3720 O O      . ILE   E 1 353 ? 279.334 226.975 191.341 1.00 45.36  ? 365 ILE   B O      1 
ATOM   3721 C CB     . ILE   E 1 353 ? 281.343 229.388 190.729 1.00 43.93  ? 365 ILE   B CB     1 
ATOM   3722 C CG1    . ILE   E 1 353 ? 281.600 230.886 190.868 1.00 42.12  ? 365 ILE   B CG1    1 
ATOM   3723 C CG2    . ILE   E 1 353 ? 282.222 228.810 189.638 1.00 45.09  ? 365 ILE   B CG2    1 
ATOM   3724 C CD1    . ILE   E 1 353 ? 281.361 231.659 189.599 1.00 41.83  ? 365 ILE   B CD1    1 
ATOM   3725 N N      . ALA   E 1 354 ? 279.588 227.113 189.107 1.00 42.71  ? 366 ALA   B N      1 
ATOM   3726 C CA     . ALA   E 1 354 ? 279.248 225.724 188.849 1.00 44.79  ? 366 ALA   B CA     1 
ATOM   3727 C C      . ALA   E 1 354 ? 280.472 224.830 188.992 1.00 46.88  ? 366 ALA   B C      1 
ATOM   3728 O O      . ALA   E 1 354 ? 281.614 225.294 188.959 1.00 49.10  ? 366 ALA   B O      1 
ATOM   3729 C CB     . ALA   E 1 354 ? 278.649 225.562 187.452 1.00 45.07  ? 366 ALA   B CB     1 
ATOM   3730 N N      . SER   E 1 355 ? 280.217 223.532 189.156 1.00 44.67  ? 367 SER   B N      1 
ATOM   3731 C CA     . SER   E 1 355 ? 281.309 222.574 189.290 1.00 43.43  ? 367 SER   B CA     1 
ATOM   3732 C C      . SER   E 1 355 ? 282.097 222.435 187.993 1.00 46.01  ? 367 SER   B C      1 
ATOM   3733 O O      . SER   E 1 355 ? 283.324 222.286 188.020 1.00 46.44  ? 367 SER   B O      1 
ATOM   3734 C CB     . SER   E 1 355 ? 280.761 221.219 189.733 1.00 39.92  ? 367 SER   B CB     1 
ATOM   3735 O OG     . SER   E 1 355 ? 281.738 220.207 189.585 1.00 50.27  ? 367 SER   B OG     1 
ATOM   3736 N N      . ASN   E 1 356 ? 281.415 222.470 186.850 1.00 45.94  ? 368 ASN   B N      1 
ATOM   3737 C CA     . ASN   E 1 356 ? 282.056 222.187 185.571 1.00 45.65  ? 368 ASN   B CA     1 
ATOM   3738 C C      . ASN   E 1 356 ? 282.847 223.377 185.042 1.00 48.65  ? 368 ASN   B C      1 
ATOM   3739 O O      . ASN   E 1 356 ? 283.385 223.318 183.933 1.00 51.88  ? 368 ASN   B O      1 
ATOM   3740 C CB     . ASN   E 1 356 ? 281.014 221.764 184.535 1.00 42.61  ? 368 ASN   B CB     1 
ATOM   3741 C CG     . ASN   E 1 356 ? 279.778 222.631 184.570 1.00 47.46  ? 368 ASN   B CG     1 
ATOM   3742 O OD1    . ASN   E 1 356 ? 279.724 223.678 183.929 1.00 50.97  ? 368 ASN   B OD1    1 
ATOM   3743 N ND2    . ASN   E 1 356 ? 278.777 222.203 185.327 1.00 49.34  ? 368 ASN   B ND2    1 
ATOM   3744 N N      . GLU   E 1 357 ? 282.934 224.454 185.814 1.00 48.74  ? 369 GLU   B N      1 
ATOM   3745 C CA     . GLU   E 1 357 ? 283.550 225.691 185.352 1.00 50.94  ? 369 GLU   B CA     1 
ATOM   3746 C C      . GLU   E 1 357 ? 285.046 225.651 185.620 1.00 50.28  ? 369 GLU   B C      1 
ATOM   3747 O O      . GLU   E 1 357 ? 285.478 225.249 186.705 1.00 54.24  ? 369 GLU   B O      1 
ATOM   3748 C CB     . GLU   E 1 357 ? 282.919 226.911 186.024 1.00 50.85  ? 369 GLU   B CB     1 
ATOM   3749 C CG     . GLU   E 1 357 ? 281.496 227.182 185.565 1.00 51.04  ? 369 GLU   B CG     1 
ATOM   3750 C CD     . GLU   E 1 357 ? 281.214 228.653 185.350 1.00 55.07  ? 369 GLU   B CD     1 
ATOM   3751 O OE1    . GLU   E 1 357 ? 282.168 229.409 185.081 1.00 63.48  ? 369 GLU   B OE1    1 
ATOM   3752 O OE2    . GLU   E 1 357 ? 280.035 229.051 185.441 1.00 53.75  ? 369 GLU   B OE2    1 
ATOM   3753 N N      . ASN   E 1 358 ? 285.828 226.069 184.630 1.00 49.95  ? 370 ASN   B N      1 
ATOM   3754 C CA     . ASN   E 1 358 ? 287.283 226.058 184.731 1.00 53.12  ? 370 ASN   B CA     1 
ATOM   3755 C C      . ASN   E 1 358 ? 287.671 227.103 185.765 1.00 55.83  ? 370 ASN   B C      1 
ATOM   3756 O O      . ASN   E 1 358 ? 287.659 228.305 185.491 1.00 56.13  ? 370 ASN   B O      1 
ATOM   3757 C CB     . ASN   E 1 358 ? 287.900 226.336 183.361 1.00 55.69  ? 370 ASN   B CB     1 
ATOM   3758 C CG     . ASN   E 1 358 ? 289.341 226.841 183.426 1.00 65.66  ? 370 ASN   B CG     1 
ATOM   3759 O OD1    . ASN   E 1 358 ? 289.863 227.191 184.483 1.00 68.66  ? 370 ASN   B OD1    1 
ATOM   3760 N ND2    . ASN   E 1 358 ? 289.990 226.875 182.270 1.00 68.78  ? 370 ASN   B ND2    1 
ATOM   3761 N N      . MET   E 1 359 ? 288.017 226.648 186.967 1.00 57.92  ? 371 MET   B N      1 
ATOM   3762 C CA     . MET   E 1 359 ? 288.354 227.566 188.045 1.00 57.09  ? 371 MET   B CA     1 
ATOM   3763 C C      . MET   E 1 359 ? 289.815 227.979 187.939 1.00 57.88  ? 371 MET   B C      1 
ATOM   3764 O O      . MET   E 1 359 ? 290.561 227.920 188.921 1.00 62.91  ? 371 MET   B O      1 
ATOM   3765 C CB     . MET   E 1 359 ? 288.064 226.921 189.402 1.00 48.71  ? 371 MET   B CB     1 
ATOM   3766 C CG     . MET   E 1 359 ? 286.783 227.413 190.052 1.00 45.88  ? 371 MET   B CG     1 
ATOM   3767 S SD     . MET   E 1 359 ? 286.979 228.951 190.965 1.00 67.27  ? 371 MET   B SD     1 
ATOM   3768 C CE     . MET   E 1 359 ? 288.575 228.684 191.723 1.00 54.53  ? 371 MET   B CE     1 
ATOM   3769 N N      . GLU   E 1 360 ? 290.224 228.406 186.747 1.00 54.34  ? 372 GLU   B N      1 
ATOM   3770 C CA     . GLU   E 1 360 ? 291.573 228.901 186.512 1.00 57.49  ? 372 GLU   B CA     1 
ATOM   3771 C C      . GLU   E 1 360 ? 291.615 230.208 185.740 1.00 61.01  ? 372 GLU   B C      1 
ATOM   3772 O O      . GLU   E 1 360 ? 292.602 230.942 185.867 1.00 67.18  ? 372 GLU   B O      1 
ATOM   3773 C CB     . GLU   E 1 360 ? 292.407 227.854 185.759 1.00 61.03  ? 372 GLU   B CB     1 
ATOM   3774 C CG     . GLU   E 1 360 ? 293.586 228.427 185.004 1.00 68.57  ? 372 GLU   B CG     1 
ATOM   3775 C CD     . GLU   E 1 360 ? 294.838 227.598 185.175 1.00 84.51  ? 372 GLU   B CD     1 
ATOM   3776 O OE1    . GLU   E 1 360 ? 294.803 226.622 185.953 1.00 86.54  ? 372 GLU   B OE1    1 
ATOM   3777 O OE2    . GLU   E 1 360 ? 295.858 227.922 184.533 1.00 93.56  ? 372 GLU   B OE2    1 
ATOM   3778 N N      . THR   E 1 361 ? 290.589 230.528 184.958 1.00 58.69  ? 373 THR   B N      1 
ATOM   3779 C CA     . THR   E 1 361 ? 290.463 231.824 184.311 1.00 58.60  ? 373 THR   B CA     1 
ATOM   3780 C C      . THR   E 1 361 ? 289.577 232.773 185.103 1.00 55.14  ? 373 THR   B C      1 
ATOM   3781 O O      . THR   E 1 361 ? 289.157 233.804 184.571 1.00 59.20  ? 373 THR   B O      1 
ATOM   3782 C CB     . THR   E 1 361 ? 289.911 231.659 182.895 1.00 59.23  ? 373 THR   B CB     1 
ATOM   3783 O OG1    . THR   E 1 361 ? 288.529 231.289 182.961 1.00 63.07  ? 373 THR   B OG1    1 
ATOM   3784 C CG2    . THR   E 1 361 ? 290.678 230.581 182.150 1.00 61.73  ? 373 THR   B CG2    1 
ATOM   3785 N N      . MET   E 1 362 ? 289.286 232.446 186.357 1.00 52.84  ? 374 MET   B N      1 
ATOM   3786 C CA     . MET   E 1 362 ? 288.374 233.219 187.186 1.00 51.87  ? 374 MET   B CA     1 
ATOM   3787 C C      . MET   E 1 362 ? 289.165 234.200 188.038 1.00 49.73  ? 374 MET   B C      1 
ATOM   3788 O O      . MET   E 1 362 ? 290.155 233.823 188.672 1.00 52.60  ? 374 MET   B O      1 
ATOM   3789 C CB     . MET   E 1 362 ? 287.542 232.297 188.078 1.00 47.57  ? 374 MET   B CB     1 
ATOM   3790 C CG     . MET   E 1 362 ? 286.677 231.312 187.313 1.00 51.74  ? 374 MET   B CG     1 
ATOM   3791 S SD     . MET   E 1 362 ? 285.026 231.145 188.007 1.00 54.03  ? 374 MET   B SD     1 
ATOM   3792 C CE     . MET   E 1 362 ? 284.511 232.856 188.038 1.00 49.02  ? 374 MET   B CE     1 
ATOM   3793 N N      . GLU   E 1 363 ? 288.730 235.455 188.042 1.00 49.57  ? 375 GLU   B N      1 
ATOM   3794 C CA     . GLU   E 1 363 ? 289.326 236.490 188.869 1.00 51.76  ? 375 GLU   B CA     1 
ATOM   3795 C C      . GLU   E 1 363 ? 288.278 237.043 189.825 1.00 50.65  ? 375 GLU   B C      1 
ATOM   3796 O O      . GLU   E 1 363 ? 287.073 236.902 189.600 1.00 50.37  ? 375 GLU   B O      1 
ATOM   3797 C CB     . GLU   E 1 363 ? 289.913 237.623 188.018 1.00 53.24  ? 375 GLU   B CB     1 
ATOM   3798 C CG     . GLU   E 1 363 ? 288.939 238.235 187.030 1.00 57.32  ? 375 GLU   B CG     1 
ATOM   3799 C CD     . GLU   E 1 363 ? 289.617 238.683 185.753 1.00 66.14  ? 375 GLU   B CD     1 
ATOM   3800 O OE1    . GLU   E 1 363 ? 288.938 238.753 184.708 1.00 65.16  ? 375 GLU   B OE1    1 
ATOM   3801 O OE2    . GLU   E 1 363 ? 290.831 238.969 185.795 1.00 73.83  ? 375 GLU   B OE2    1 
ATOM   3802 N N      . SER   E 1 364 ? 288.749 237.665 190.899 1.00 49.14  ? 376 SER   B N      1 
ATOM   3803 C CA     . SER   E 1 364 ? 287.881 238.204 191.934 1.00 49.63  ? 376 SER   B CA     1 
ATOM   3804 C C      . SER   E 1 364 ? 287.872 239.724 191.875 1.00 48.78  ? 376 SER   B C      1 
ATOM   3805 O O      . SER   E 1 364 ? 288.883 240.349 191.543 1.00 49.50  ? 376 SER   B O      1 
ATOM   3806 C CB     . SER   E 1 364 ? 288.336 237.742 193.318 1.00 53.39  ? 376 SER   B CB     1 
ATOM   3807 O OG     . SER   E 1 364 ? 289.544 238.379 193.689 1.00 56.74  ? 376 SER   B OG     1 
ATOM   3808 N N      . SER   E 1 365 ? 286.723 240.314 192.196 1.00 50.10  ? 377 SER   B N      1 
ATOM   3809 C CA     . SER   E 1 365 ? 286.566 241.759 192.215 1.00 49.37  ? 377 SER   B CA     1 
ATOM   3810 C C      . SER   E 1 365 ? 285.744 242.176 193.426 1.00 47.53  ? 377 SER   B C      1 
ATOM   3811 O O      . SER   E 1 365 ? 284.961 241.392 193.967 1.00 45.77  ? 377 SER   B O      1 
ATOM   3812 C CB     . SER   E 1 365 ? 285.897 242.267 190.935 1.00 48.22  ? 377 SER   B CB     1 
ATOM   3813 O OG     . SER   E 1 365 ? 284.499 242.052 190.979 1.00 55.90  ? 377 SER   B OG     1 
ATOM   3814 N N      . THR   E 1 366 ? 285.938 243.421 193.850 1.00 46.37  ? 378 THR   B N      1 
ATOM   3815 C CA     . THR   E 1 366 ? 285.155 243.969 194.947 1.00 44.83  ? 378 THR   B CA     1 
ATOM   3816 C C      . THR   E 1 366 ? 283.783 244.411 194.452 1.00 43.52  ? 378 THR   B C      1 
ATOM   3817 O O      . THR   E 1 366 ? 283.656 245.024 193.390 1.00 42.91  ? 378 THR   B O      1 
ATOM   3818 C CB     . THR   E 1 366 ? 285.886 245.149 195.585 1.00 45.18  ? 378 THR   B CB     1 
ATOM   3819 O OG1    . THR   E 1 366 ? 287.279 244.839 195.707 1.00 41.93  ? 378 THR   B OG1    1 
ATOM   3820 C CG2    . THR   E 1 366 ? 285.319 245.441 196.961 1.00 50.03  ? 378 THR   B CG2    1 
ATOM   3821 N N      . LEU   E 1 367 ? 282.752 244.093 195.228 1.00 45.90  ? 379 LEU   B N      1 
ATOM   3822 C CA     . LEU   E 1 367 ? 281.385 244.452 194.881 1.00 46.25  ? 379 LEU   B CA     1 
ATOM   3823 C C      . LEU   E 1 367 ? 281.075 245.853 195.387 1.00 46.95  ? 379 LEU   B C      1 
ATOM   3824 O O      . LEU   E 1 367 ? 281.339 246.173 196.550 1.00 49.77  ? 379 LEU   B O      1 
ATOM   3825 C CB     . LEU   E 1 367 ? 280.392 243.448 195.465 1.00 43.65  ? 379 LEU   B CB     1 
ATOM   3826 C CG     . LEU   E 1 367 ? 280.500 241.999 194.994 1.00 42.63  ? 379 LEU   B CG     1 
ATOM   3827 C CD1    . LEU   E 1 367 ? 279.595 241.109 195.824 1.00 46.24  ? 379 LEU   B CD1    1 
ATOM   3828 C CD2    . LEU   E 1 367 ? 280.157 241.888 193.523 1.00 41.13  ? 379 LEU   B CD2    1 
ATOM   3829 N N      . GLU   E 1 368 ? 280.509 246.683 194.513 1.00 46.09  ? 380 GLU   B N      1 
ATOM   3830 C CA     . GLU   E 1 368 ? 280.149 248.054 194.869 1.00 47.08  ? 380 GLU   B CA     1 
ATOM   3831 C C      . GLU   E 1 368 ? 278.715 248.058 195.387 1.00 47.08  ? 380 GLU   B C      1 
ATOM   3832 O O      . GLU   E 1 368 ? 277.764 248.429 194.697 1.00 46.36  ? 380 GLU   B O      1 
ATOM   3833 C CB     . GLU   E 1 368 ? 280.323 248.979 193.673 1.00 50.15  ? 380 GLU   B CB     1 
ATOM   3834 C CG     . GLU   E 1 368 ? 281.389 250.037 193.864 1.00 56.56  ? 380 GLU   B CG     1 
ATOM   3835 C CD     . GLU   E 1 368 ? 281.081 250.965 195.017 1.00 67.07  ? 380 GLU   B CD     1 
ATOM   3836 O OE1    . GLU   E 1 368 ? 282.002 251.673 195.474 1.00 74.67  ? 380 GLU   B OE1    1 
ATOM   3837 O OE2    . GLU   E 1 368 ? 279.917 250.989 195.467 1.00 65.30  ? 380 GLU   B OE2    1 
ATOM   3838 N N      . LEU   E 1 369 ? 278.563 247.626 196.634 1.00 47.42  ? 381 LEU   B N      1 
ATOM   3839 C CA     . LEU   E 1 369 ? 277.253 247.598 197.283 1.00 47.59  ? 381 LEU   B CA     1 
ATOM   3840 C C      . LEU   E 1 369 ? 276.994 248.882 198.063 1.00 49.07  ? 381 LEU   B C      1 
ATOM   3841 O O      . LEU   E 1 369 ? 276.637 248.856 199.239 1.00 50.68  ? 381 LEU   B O      1 
ATOM   3842 C CB     . LEU   E 1 369 ? 277.153 246.378 198.189 1.00 44.64  ? 381 LEU   B CB     1 
ATOM   3843 C CG     . LEU   E 1 369 ? 277.406 245.022 197.533 1.00 41.80  ? 381 LEU   B CG     1 
ATOM   3844 C CD1    . LEU   E 1 369 ? 277.250 243.904 198.544 1.00 40.79  ? 381 LEU   B CD1    1 
ATOM   3845 C CD2    . LEU   E 1 369 ? 276.468 244.817 196.358 1.00 46.16  ? 381 LEU   B CD2    1 
ATOM   3846 N N      . ARG   E 1 370 ? 277.164 250.022 197.403 1.00 47.76  ? 382 ARG   B N      1 
ATOM   3847 C CA     . ARG   E 1 370 ? 276.971 251.322 198.024 1.00 46.48  ? 382 ARG   B CA     1 
ATOM   3848 C C      . ARG   E 1 370 ? 275.894 252.096 197.283 1.00 45.92  ? 382 ARG   B C      1 
ATOM   3849 O O      . ARG   E 1 370 ? 275.902 252.168 196.051 1.00 47.69  ? 382 ARG   B O      1 
ATOM   3850 C CB     . ARG   E 1 370 ? 278.269 252.131 198.047 1.00 47.72  ? 382 ARG   B CB     1 
ATOM   3851 C CG     . ARG   E 1 370 ? 279.098 251.910 199.293 1.00 51.20  ? 382 ARG   B CG     1 
ATOM   3852 C CD     . ARG   E 1 370 ? 280.579 251.960 198.988 1.00 53.97  ? 382 ARG   B CD     1 
ATOM   3853 N NE     . ARG   E 1 370 ? 280.891 252.972 197.990 1.00 59.97  ? 382 ARG   B NE     1 
ATOM   3854 C CZ     . ARG   E 1 370 ? 281.846 253.882 198.124 1.00 70.43  ? 382 ARG   B CZ     1 
ATOM   3855 N NH1    . ARG   E 1 370 ? 282.594 253.941 199.213 1.00 66.95  ? 382 ARG   B NH1    1 
ATOM   3856 N NH2    . ARG   E 1 370 ? 282.053 254.754 197.143 1.00 77.90  ? 382 ARG   B NH2    1 
ATOM   3857 N N      . SER   E 1 371 ? 274.974 252.676 198.043 1.00 43.81  ? 383 SER   B N      1 
ATOM   3858 C CA     . SER   E 1 371 ? 273.872 253.451 197.501 1.00 43.16  ? 383 SER   B CA     1 
ATOM   3859 C C      . SER   E 1 371 ? 274.030 254.906 197.908 1.00 44.00  ? 383 SER   B C      1 
ATOM   3860 O O      . SER   E 1 371 ? 274.425 255.205 199.040 1.00 48.52  ? 383 SER   B O      1 
ATOM   3861 C CB     . SER   E 1 371 ? 272.528 252.915 197.989 1.00 44.84  ? 383 SER   B CB     1 
ATOM   3862 O OG     . SER   E 1 371 ? 272.611 252.524 199.346 1.00 50.00  ? 383 SER   B OG     1 
ATOM   3863 N N      . ARG   E 1 372 ? 273.733 255.809 196.976 1.00 41.58  ? 384 ARG   B N      1 
ATOM   3864 C CA     . ARG   E 1 372 ? 273.816 257.231 197.282 1.00 43.02  ? 384 ARG   B CA     1 
ATOM   3865 C C      . ARG   E 1 372 ? 272.764 257.637 198.308 1.00 45.34  ? 384 ARG   B C      1 
ATOM   3866 O O      . ARG   E 1 372 ? 273.038 258.449 199.198 1.00 45.69  ? 384 ARG   B O      1 
ATOM   3867 C CB     . ARG   E 1 372 ? 273.671 258.046 196.000 1.00 42.79  ? 384 ARG   B CB     1 
ATOM   3868 C CG     . ARG   E 1 372 ? 273.924 259.524 196.179 1.00 44.19  ? 384 ARG   B CG     1 
ATOM   3869 C CD     . ARG   E 1 372 ? 273.903 260.245 194.847 1.00 48.11  ? 384 ARG   B CD     1 
ATOM   3870 N NE     . ARG   E 1 372 ? 273.131 261.481 194.890 1.00 58.64  ? 384 ARG   B NE     1 
ATOM   3871 C CZ     . ARG   E 1 372 ? 273.270 262.427 195.809 1.00 65.68  ? 384 ARG   B CZ     1 
ATOM   3872 N NH1    . ARG   E 1 372 ? 274.154 262.320 196.787 1.00 65.55  ? 384 ARG   B NH1    1 
ATOM   3873 N NH2    . ARG   E 1 372 ? 272.509 263.516 195.738 1.00 72.03  ? 384 ARG   B NH2    1 
ATOM   3874 N N      . TYR   E 1 373 ? 271.563 257.080 198.209 1.00 45.36  ? 385 TYR   B N      1 
ATOM   3875 C CA     . TYR   E 1 373 ? 270.467 257.392 199.117 1.00 43.60  ? 385 TYR   B CA     1 
ATOM   3876 C C      . TYR   E 1 373 ? 270.012 256.119 199.830 1.00 44.12  ? 385 TYR   B C      1 
ATOM   3877 O O      . TYR   E 1 373 ? 270.442 255.010 199.503 1.00 43.67  ? 385 TYR   B O      1 
ATOM   3878 C CB     . TYR   E 1 373 ? 269.308 258.042 198.357 1.00 45.56  ? 385 TYR   B CB     1 
ATOM   3879 C CG     . TYR   E 1 373 ? 269.598 259.429 197.838 1.00 45.52  ? 385 TYR   B CG     1 
ATOM   3880 C CD1    . TYR   E 1 373 ? 269.896 260.468 198.705 1.00 49.78  ? 385 TYR   B CD1    1 
ATOM   3881 C CD2    . TYR   E 1 373 ? 269.569 259.700 196.479 1.00 47.81  ? 385 TYR   B CD2    1 
ATOM   3882 C CE1    . TYR   E 1 373 ? 270.158 261.736 198.232 1.00 53.17  ? 385 TYR   B CE1    1 
ATOM   3883 C CE2    . TYR   E 1 373 ? 269.832 260.963 195.998 1.00 48.05  ? 385 TYR   B CE2    1 
ATOM   3884 C CZ     . TYR   E 1 373 ? 270.124 261.977 196.878 1.00 52.73  ? 385 TYR   B CZ     1 
ATOM   3885 O OH     . TYR   E 1 373 ? 270.386 263.239 196.402 1.00 61.94  ? 385 TYR   B OH     1 
ATOM   3886 N N      . TRP   E 1 374 ? 269.121 256.284 200.804 1.00 43.53  ? 386 TRP   B N      1 
ATOM   3887 C CA     . TRP   E 1 374 ? 268.547 255.147 201.506 1.00 44.15  ? 386 TRP   B CA     1 
ATOM   3888 C C      . TRP   E 1 374 ? 267.062 255.396 201.711 1.00 44.95  ? 386 TRP   B C      1 
ATOM   3889 O O      . TRP   E 1 374 ? 266.644 256.525 201.975 1.00 47.88  ? 386 TRP   B O      1 
ATOM   3890 C CB     . TRP   E 1 374 ? 269.252 254.891 202.846 1.00 43.00  ? 386 TRP   B CB     1 
ATOM   3891 C CG     . TRP   E 1 374 ? 268.757 255.708 204.002 1.00 43.07  ? 386 TRP   B CG     1 
ATOM   3892 C CD1    . TRP   E 1 374 ? 269.244 256.909 204.426 1.00 45.84  ? 386 TRP   B CD1    1 
ATOM   3893 C CD2    . TRP   E 1 374 ? 267.694 255.370 204.899 1.00 41.96  ? 386 TRP   B CD2    1 
ATOM   3894 N NE1    . TRP   E 1 374 ? 268.546 257.344 205.525 1.00 43.79  ? 386 TRP   B NE1    1 
ATOM   3895 C CE2    . TRP   E 1 374 ? 267.586 256.417 205.834 1.00 43.56  ? 386 TRP   B CE2    1 
ATOM   3896 C CE3    . TRP   E 1 374 ? 266.818 254.287 204.999 1.00 41.57  ? 386 TRP   B CE3    1 
ATOM   3897 C CZ2    . TRP   E 1 374 ? 266.640 256.411 206.854 1.00 44.52  ? 386 TRP   B CZ2    1 
ATOM   3898 C CZ3    . TRP   E 1 374 ? 265.880 254.284 206.010 1.00 40.72  ? 386 TRP   B CZ3    1 
ATOM   3899 C CH2    . TRP   E 1 374 ? 265.798 255.338 206.924 1.00 40.72  ? 386 TRP   B CH2    1 
ATOM   3900 N N      . ALA   E 1 375 ? 266.272 254.334 201.577 1.00 44.33  ? 387 ALA   B N      1 
ATOM   3901 C CA     . ALA   E 1 375 ? 264.824 254.428 201.667 1.00 43.83  ? 387 ALA   B CA     1 
ATOM   3902 C C      . ALA   E 1 375 ? 264.305 253.339 202.593 1.00 42.66  ? 387 ALA   B C      1 
ATOM   3903 O O      . ALA   E 1 375 ? 265.030 252.419 202.976 1.00 43.61  ? 387 ALA   B O      1 
ATOM   3904 C CB     . ALA   E 1 375 ? 264.164 254.312 200.288 1.00 44.62  ? 387 ALA   B CB     1 
ATOM   3905 N N      . ILE   E 1 376 ? 263.037 253.466 202.961 1.00 42.73  ? 388 ILE   B N      1 
ATOM   3906 C CA     . ILE   E 1 376 ? 262.379 252.505 203.835 1.00 43.24  ? 388 ILE   B CA     1 
ATOM   3907 C C      . ILE   E 1 376 ? 261.637 251.490 202.979 1.00 43.78  ? 388 ILE   B C      1 
ATOM   3908 O O      . ILE   E 1 376 ? 260.845 251.860 202.105 1.00 47.42  ? 388 ILE   B O      1 
ATOM   3909 C CB     . ILE   E 1 376 ? 261.422 253.213 204.806 1.00 43.98  ? 388 ILE   B CB     1 
ATOM   3910 C CG1    . ILE   E 1 376 ? 262.211 254.051 205.809 1.00 44.18  ? 388 ILE   B CG1    1 
ATOM   3911 C CG2    . ILE   E 1 376 ? 260.554 252.200 205.527 1.00 45.95  ? 388 ILE   B CG2    1 
ATOM   3912 C CD1    . ILE   E 1 376 ? 261.406 255.161 206.439 1.00 47.52  ? 388 ILE   B CD1    1 
ATOM   3913 N N      . ARG   E 1 377 ? 261.898 250.210 203.223 1.00 41.67  ? 389 ARG   B N      1 
ATOM   3914 C CA     . ARG   E 1 377 ? 261.210 249.154 202.497 1.00 42.35  ? 389 ARG   B CA     1 
ATOM   3915 C C      . ARG   E 1 377 ? 259.762 249.047 202.963 1.00 42.97  ? 389 ARG   B C      1 
ATOM   3916 O O      . ARG   E 1 377 ? 259.454 249.191 204.149 1.00 45.07  ? 389 ARG   B O      1 
ATOM   3917 C CB     . ARG   E 1 377 ? 261.937 247.824 202.689 1.00 41.44  ? 389 ARG   B CB     1 
ATOM   3918 C CG     . ARG   E 1 377 ? 263.083 247.605 201.717 1.00 38.32  ? 389 ARG   B CG     1 
ATOM   3919 C CD     . ARG   E 1 377 ? 264.273 248.486 202.056 1.00 36.53  ? 389 ARG   B CD     1 
ATOM   3920 N NE     . ARG   E 1 377 ? 264.961 248.045 203.263 1.00 39.72  ? 389 ARG   B NE     1 
ATOM   3921 C CZ     . ARG   E 1 377 ? 265.742 248.819 204.003 1.00 38.58  ? 389 ARG   B CZ     1 
ATOM   3922 N NH1    . ARG   E 1 377 ? 265.958 250.085 203.690 1.00 43.71  ? 389 ARG   B NH1    1 
ATOM   3923 N NH2    . ARG   E 1 377 ? 266.316 248.312 205.089 1.00 39.29  ? 389 ARG   B NH2    1 
ATOM   3924 N N      . THR   E 1 378 ? 258.868 248.784 202.016 1.00 43.16  ? 390 THR   B N      1 
ATOM   3925 C CA     . THR   E 1 378 ? 257.434 248.833 202.259 1.00 42.55  ? 390 THR   B CA     1 
ATOM   3926 C C      . THR   E 1 378 ? 256.833 247.439 202.200 1.00 42.46  ? 390 THR   B C      1 
ATOM   3927 O O      . THR   E 1 378 ? 257.233 246.611 201.377 1.00 46.52  ? 390 THR   B O      1 
ATOM   3928 C CB     . THR   E 1 378 ? 256.726 249.724 201.237 1.00 47.59  ? 390 THR   B CB     1 
ATOM   3929 O OG1    . THR   E 1 378 ? 256.397 248.951 200.078 1.00 48.07  ? 390 THR   B OG1    1 
ATOM   3930 C CG2    . THR   E 1 378 ? 257.626 250.859 200.823 1.00 51.28  ? 390 THR   B CG2    1 
ATOM   3931 N N      . ARG   E 1 379 ? 255.872 247.186 203.084 1.00 40.36  ? 391 ARG   B N      1 
ATOM   3932 C CA     . ARG   E 1 379 ? 255.041 245.995 203.017 1.00 45.06  ? 391 ARG   B CA     1 
ATOM   3933 C C      . ARG   E 1 379 ? 253.684 246.283 202.393 1.00 46.08  ? 391 ARG   B C      1 
ATOM   3934 O O      . ARG   E 1 379 ? 252.796 245.426 202.434 1.00 50.53  ? 391 ARG   B O      1 
ATOM   3935 C CB     . ARG   E 1 379 ? 254.861 245.392 204.410 1.00 44.34  ? 391 ARG   B CB     1 
ATOM   3936 C CG     . ARG   E 1 379 ? 253.691 245.956 205.184 1.00 42.75  ? 391 ARG   B CG     1 
ATOM   3937 C CD     . ARG   E 1 379 ? 253.292 245.025 206.312 1.00 44.36  ? 391 ARG   B CD     1 
ATOM   3938 N NE     . ARG   E 1 379 ? 254.345 244.902 207.312 1.00 47.38  ? 391 ARG   B NE     1 
ATOM   3939 C CZ     . ARG   E 1 379 ? 254.156 245.034 208.617 1.00 54.69  ? 391 ARG   B CZ     1 
ATOM   3940 N NH1    . ARG   E 1 379 ? 252.960 245.288 209.121 1.00 57.55  ? 391 ARG   B NH1    1 
ATOM   3941 N NH2    . ARG   E 1 379 ? 255.194 244.907 209.438 1.00 56.62  ? 391 ARG   B NH2    1 
ATOM   3942 N N      . SER   E 1 380 ? 253.506 247.468 201.820 1.00 42.90  ? 392 SER   B N      1 
ATOM   3943 C CA     . SER   E 1 380 ? 252.247 247.890 201.231 1.00 47.97  ? 392 SER   B CA     1 
ATOM   3944 C C      . SER   E 1 380 ? 252.372 247.965 199.716 1.00 48.93  ? 392 SER   B C      1 
ATOM   3945 O O      . SER   E 1 380 ? 253.466 248.108 199.165 1.00 52.07  ? 392 SER   B O      1 
ATOM   3946 C CB     . SER   E 1 380 ? 251.812 249.250 201.786 1.00 46.67  ? 392 SER   B CB     1 
ATOM   3947 O OG     . SER   E 1 380 ? 252.160 250.296 200.899 1.00 41.28  ? 392 SER   B OG     1 
ATOM   3948 N N      . GLY   E 1 381 ? 251.230 247.863 199.046 1.00 48.08  ? 393 GLY   B N      1 
ATOM   3949 C CA     . GLY   E 1 381 ? 251.201 247.942 197.602 1.00 47.76  ? 393 GLY   B CA     1 
ATOM   3950 C C      . GLY   E 1 381 ? 251.027 249.362 197.112 1.00 52.77  ? 393 GLY   B C      1 
ATOM   3951 O O      . GLY   E 1 381 ? 251.808 250.248 197.466 1.00 60.82  ? 393 GLY   B O      1 
ATOM   3952 N N      . GLY   E 1 382 ? 249.999 249.595 196.305 1.00 48.44  ? 394 GLY   B N      1 
ATOM   3953 C CA     . GLY   E 1 382 ? 249.744 250.922 195.785 1.00 54.75  ? 394 GLY   B CA     1 
ATOM   3954 C C      . GLY   E 1 382 ? 248.607 251.613 196.505 1.00 59.61  ? 394 GLY   B C      1 
ATOM   3955 O O      . GLY   E 1 382 ? 248.774 252.089 197.631 1.00 51.06  ? 394 GLY   B O      1 
ATOM   3956 N N      . ASN   E 1 383 ? 247.447 251.679 195.859 1.00 65.34  ? 395 ASN   B N      1 
ATOM   3957 C CA     . ASN   E 1 383 ? 246.262 252.273 196.463 1.00 56.33  ? 395 ASN   B CA     1 
ATOM   3958 C C      . ASN   E 1 383 ? 245.053 251.360 196.285 1.00 50.73  ? 395 ASN   B C      1 
ATOM   3959 O O      . ASN   E 1 383 ? 244.031 251.766 195.733 1.00 52.62  ? 395 ASN   B O      1 
ATOM   3960 C CB     . ASN   E 1 383 ? 245.984 253.647 195.856 1.00 54.44  ? 395 ASN   B CB     1 
ATOM   3961 C CG     . ASN   E 1 383 ? 246.895 254.722 196.411 1.00 53.87  ? 395 ASN   B CG     1 
ATOM   3962 O OD1    . ASN   E 1 383 ? 247.876 254.429 197.093 1.00 51.56  ? 395 ASN   B OD1    1 
ATOM   3963 N ND2    . ASN   E 1 383 ? 246.574 255.977 196.123 1.00 54.00  ? 395 ASN   B ND2    1 
ATOM   3964 N N      . GLY   E 1 392 ? 237.453 258.621 205.541 1.00 27.51  ? 404 GLY   B N      1 
ATOM   3965 C CA     . GLY   E 1 392 ? 237.203 259.685 206.495 1.00 38.94  ? 404 GLY   B CA     1 
ATOM   3966 C C      . GLY   E 1 392 ? 236.248 259.295 207.605 1.00 47.61  ? 404 GLY   B C      1 
ATOM   3967 O O      . GLY   E 1 392 ? 235.956 258.117 207.799 1.00 53.61  ? 404 GLY   B O      1 
ATOM   3968 N N      . GLN   E 1 393 ? 235.759 260.291 208.336 1.00 44.55  ? 405 GLN   B N      1 
ATOM   3969 C CA     . GLN   E 1 393 ? 234.832 260.061 209.435 1.00 43.29  ? 405 GLN   B CA     1 
ATOM   3970 C C      . GLN   E 1 393 ? 233.421 259.866 208.899 1.00 44.54  ? 405 GLN   B C      1 
ATOM   3971 O O      . GLN   E 1 393 ? 233.000 260.544 207.959 1.00 43.74  ? 405 GLN   B O      1 
ATOM   3972 C CB     . GLN   E 1 393 ? 234.861 261.229 210.421 1.00 43.50  ? 405 GLN   B CB     1 
ATOM   3973 C CG     . GLN   E 1 393 ? 234.030 261.002 211.670 1.00 40.95  ? 405 GLN   B CG     1 
ATOM   3974 C CD     . GLN   E 1 393 ? 234.222 262.088 212.707 1.00 41.31  ? 405 GLN   B CD     1 
ATOM   3975 O OE1    . GLN   E 1 393 ? 233.502 262.146 213.700 1.00 47.87  ? 405 GLN   B OE1    1 
ATOM   3976 N NE2    . GLN   E 1 393 ? 235.200 262.954 212.482 1.00 42.40  ? 405 GLN   B NE2    1 
ATOM   3977 N N      . ILE   E 1 394 ? 232.695 258.929 209.502 1.00 43.88  ? 406 ILE   B N      1 
ATOM   3978 C CA     . ILE   E 1 394 ? 231.365 258.568 209.028 1.00 43.07  ? 406 ILE   B CA     1 
ATOM   3979 C C      . ILE   E 1 394 ? 230.369 258.563 210.179 1.00 46.85  ? 406 ILE   B C      1 
ATOM   3980 O O      . ILE   E 1 394 ? 229.205 258.189 210.000 1.00 49.43  ? 406 ILE   B O      1 
ATOM   3981 C CB     . ILE   E 1 394 ? 231.389 257.201 208.322 1.00 44.60  ? 406 ILE   B CB     1 
ATOM   3982 C CG1    . ILE   E 1 394 ? 231.561 256.078 209.345 1.00 43.46  ? 406 ILE   B CG1    1 
ATOM   3983 C CG2    . ILE   E 1 394 ? 232.498 257.153 207.291 1.00 52.22  ? 406 ILE   B CG2    1 
ATOM   3984 C CD1    . ILE   E 1 394 ? 231.677 254.708 208.729 1.00 45.72  ? 406 ILE   B CD1    1 
ATOM   3985 N N      . SER   E 1 395 ? 230.806 258.979 211.364 1.00 45.16  ? 407 SER   B N      1 
ATOM   3986 C CA     . SER   E 1 395 ? 229.941 258.937 212.534 1.00 46.55  ? 407 SER   B CA     1 
ATOM   3987 C C      . SER   E 1 395 ? 230.334 260.060 213.485 1.00 49.39  ? 407 SER   B C      1 
ATOM   3988 O O      . SER   E 1 395 ? 231.162 260.916 213.161 1.00 57.37  ? 407 SER   B O      1 
ATOM   3989 C CB     . SER   E 1 395 ? 230.012 257.564 213.211 1.00 52.65  ? 407 SER   B CB     1 
ATOM   3990 O OG     . SER   E 1 395 ? 228.927 257.384 214.102 1.00 58.65  ? 407 SER   B OG     1 
ATOM   3991 N N      . ILE   E 1 396 ? 229.729 260.050 214.673 1.00 47.32  ? 408 ILE   B N      1 
ATOM   3992 C CA     . ILE   E 1 396 ? 229.934 261.081 215.679 1.00 48.14  ? 408 ILE   B CA     1 
ATOM   3993 C C      . ILE   E 1 396 ? 230.000 260.426 217.051 1.00 52.55  ? 408 ILE   B C      1 
ATOM   3994 O O      . ILE   E 1 396 ? 229.514 259.313 217.260 1.00 59.56  ? 408 ILE   B O      1 
ATOM   3995 C CB     . ILE   E 1 396 ? 228.813 262.141 215.657 1.00 46.91  ? 408 ILE   B CB     1 
ATOM   3996 C CG1    . ILE   E 1 396 ? 229.331 263.485 216.153 1.00 47.13  ? 408 ILE   B CG1    1 
ATOM   3997 C CG2    . ILE   E 1 396 ? 227.639 261.690 216.506 1.00 51.87  ? 408 ILE   B CG2    1 
ATOM   3998 C CD1    . ILE   E 1 396 ? 228.249 264.514 216.284 1.00 50.46  ? 408 ILE   B CD1    1 
ATOM   3999 N N      . GLN   E 1 397 ? 230.617 261.135 217.993 1.00 46.71  ? 409 GLN   B N      1 
ATOM   4000 C CA     . GLN   E 1 397 ? 230.632 260.729 219.394 1.00 46.49  ? 409 GLN   B CA     1 
ATOM   4001 C C      . GLN   E 1 397 ? 230.307 261.956 220.230 1.00 47.64  ? 409 GLN   B C      1 
ATOM   4002 O O      . GLN   E 1 397 ? 231.116 262.906 220.274 1.00 48.67  ? 409 GLN   B O      1 
ATOM   4003 C CB     . GLN   E 1 397 ? 231.980 260.126 219.795 1.00 44.54  ? 409 GLN   B CB     1 
ATOM   4004 C CG     . GLN   E 1 397 ? 232.051 259.711 221.251 1.00 45.02  ? 409 GLN   B CG     1 
ATOM   4005 C CD     . GLN   E 1 397 ? 231.233 258.469 221.540 1.00 43.44  ? 409 GLN   B CD     1 
ATOM   4006 O OE1    . GLN   E 1 397 ? 230.976 257.662 220.652 1.00 44.18  ? 409 GLN   B OE1    1 
ATOM   4007 N NE2    . GLN   E 1 397 ? 230.814 258.316 222.789 1.00 42.00  ? 409 GLN   B NE2    1 
ATOM   4008 N N      . PRO   E 1 398 ? 229.154 261.999 220.895 1.00 45.66  ? 410 PRO   B N      1 
ATOM   4009 C CA     . PRO   E 1 398 ? 228.786 263.200 221.650 1.00 45.37  ? 410 PRO   B CA     1 
ATOM   4010 C C      . PRO   E 1 398 ? 229.790 263.501 222.751 1.00 45.44  ? 410 PRO   B C      1 
ATOM   4011 O O      . PRO   E 1 398 ? 230.311 262.600 223.410 1.00 50.61  ? 410 PRO   B O      1 
ATOM   4012 C CB     . PRO   E 1 398 ? 227.409 262.847 222.225 1.00 46.04  ? 410 PRO   B CB     1 
ATOM   4013 C CG     . PRO   E 1 398 ? 227.361 261.355 222.202 1.00 47.62  ? 410 PRO   B CG     1 
ATOM   4014 C CD     . PRO   E 1 398 ? 228.117 260.961 220.977 1.00 46.34  ? 410 PRO   B CD     1 
ATOM   4015 N N      . THR   E 1 399 ? 230.056 264.786 222.943 1.00 44.78  ? 411 THR   B N      1 
ATOM   4016 C CA     . THR   E 1 399 ? 230.925 265.269 224.007 1.00 43.39  ? 411 THR   B CA     1 
ATOM   4017 C C      . THR   E 1 399 ? 230.202 266.169 224.993 1.00 42.77  ? 411 THR   B C      1 
ATOM   4018 O O      . THR   E 1 399 ? 230.479 266.110 226.192 1.00 42.69  ? 411 THR   B O      1 
ATOM   4019 C CB     . THR   E 1 399 ? 232.124 266.023 223.414 1.00 44.12  ? 411 THR   B CB     1 
ATOM   4020 O OG1    . THR   E 1 399 ? 233.075 265.085 222.900 1.00 54.36  ? 411 THR   B OG1    1 
ATOM   4021 C CG2    . THR   E 1 399 ? 232.794 266.877 224.473 1.00 41.27  ? 411 THR   B CG2    1 
ATOM   4022 N N      . PHE   E 1 400 ? 229.279 266.997 224.518 1.00 43.79  ? 412 PHE   B N      1 
ATOM   4023 C CA     . PHE   E 1 400 ? 228.526 267.918 225.354 1.00 42.84  ? 412 PHE   B CA     1 
ATOM   4024 C C      . PHE   E 1 400 ? 227.079 267.459 225.474 1.00 42.88  ? 412 PHE   B C      1 
ATOM   4025 O O      . PHE   E 1 400 ? 226.533 266.825 224.568 1.00 43.79  ? 412 PHE   B O      1 
ATOM   4026 C CB     . PHE   E 1 400 ? 228.571 269.334 224.777 1.00 40.52  ? 412 PHE   B CB     1 
ATOM   4027 C CG     . PHE   E 1 400 ? 229.957 269.885 224.630 1.00 38.05  ? 412 PHE   B CG     1 
ATOM   4028 C CD1    . PHE   E 1 400 ? 230.670 270.311 225.735 1.00 38.76  ? 412 PHE   B CD1    1 
ATOM   4029 C CD2    . PHE   E 1 400 ? 230.549 269.973 223.383 1.00 37.58  ? 412 PHE   B CD2    1 
ATOM   4030 C CE1    . PHE   E 1 400 ? 231.946 270.817 225.598 1.00 39.98  ? 412 PHE   B CE1    1 
ATOM   4031 C CE2    . PHE   E 1 400 ? 231.825 270.474 223.242 1.00 38.24  ? 412 PHE   B CE2    1 
ATOM   4032 C CZ     . PHE   E 1 400 ? 232.524 270.897 224.351 1.00 39.93  ? 412 PHE   B CZ     1 
ATOM   4033 N N      . SER   E 1 401 ? 226.460 267.790 226.605 1.00 43.35  ? 413 SER   B N      1 
ATOM   4034 C CA     . SER   E 1 401 ? 225.052 267.475 226.844 1.00 44.60  ? 413 SER   B CA     1 
ATOM   4035 C C      . SER   E 1 401 ? 224.198 268.513 226.128 1.00 47.26  ? 413 SER   B C      1 
ATOM   4036 O O      . SER   E 1 401 ? 223.805 269.529 226.700 1.00 53.53  ? 413 SER   B O      1 
ATOM   4037 C CB     . SER   E 1 401 ? 224.746 267.447 228.336 1.00 43.08  ? 413 SER   B CB     1 
ATOM   4038 O OG     . SER   E 1 401 ? 225.202 266.250 228.937 1.00 54.42  ? 413 SER   B OG     1 
ATOM   4039 N N      . VAL   E 1 402 ? 223.906 268.254 224.856 1.00 44.07  ? 414 VAL   B N      1 
ATOM   4040 C CA     . VAL   E 1 402 ? 223.067 269.137 224.057 1.00 44.97  ? 414 VAL   B CA     1 
ATOM   4041 C C      . VAL   E 1 402 ? 222.023 268.300 223.330 1.00 49.58  ? 414 VAL   B C      1 
ATOM   4042 O O      . VAL   E 1 402 ? 222.234 267.117 223.048 1.00 52.56  ? 414 VAL   B O      1 
ATOM   4043 C CB     . VAL   E 1 402 ? 223.896 269.971 223.057 1.00 46.77  ? 414 VAL   B CB     1 
ATOM   4044 C CG1    . VAL   E 1 402 ? 223.066 271.116 222.510 1.00 49.60  ? 414 VAL   B CG1    1 
ATOM   4045 C CG2    . VAL   E 1 402 ? 225.154 270.495 223.723 1.00 44.21  ? 414 VAL   B CG2    1 
ATOM   4046 N N      . GLN   E 1 403 ? 220.895 268.935 223.008 1.00 49.20  ? 415 GLN   B N      1 
ATOM   4047 C CA     . GLN   E 1 403 ? 219.706 268.315 222.419 1.00 49.59  ? 415 GLN   B CA     1 
ATOM   4048 C C      . GLN   E 1 403 ? 219.876 267.965 220.928 1.00 52.05  ? 415 GLN   B C      1 
ATOM   4049 O O      . GLN   E 1 403 ? 218.918 267.565 220.255 1.00 60.50  ? 415 GLN   B O      1 
ATOM   4050 C CB     . GLN   E 1 403 ? 218.505 269.245 222.629 1.00 48.48  ? 415 GLN   B CB     1 
ATOM   4051 C CG     . GLN   E 1 403 ? 217.331 269.030 221.687 1.00 46.98  ? 415 GLN   B CG     1 
ATOM   4052 C CD     . GLN   E 1 403 ? 215.991 269.309 222.329 1.00 49.84  ? 415 GLN   B CD     1 
ATOM   4053 O OE1    . GLN   E 1 403 ? 215.873 270.178 223.191 1.00 62.11  ? 415 GLN   B OE1    1 
ATOM   4054 N NE2    . GLN   E 1 403 ? 214.971 268.570 221.914 1.00 50.86  ? 415 GLN   B NE2    1 
ATOM   4055 N N      . ARG   E 1 404 ? 221.081 268.047 220.376 1.00 49.96  ? 416 ARG   B N      1 
ATOM   4056 C CA     . ARG   E 1 404 ? 221.271 267.818 218.954 1.00 50.31  ? 416 ARG   B CA     1 
ATOM   4057 C C      . ARG   E 1 404 ? 220.891 266.385 218.584 1.00 51.48  ? 416 ARG   B C      1 
ATOM   4058 O O      . ARG   E 1 404 ? 220.480 265.576 219.420 1.00 51.05  ? 416 ARG   B O      1 
ATOM   4059 C CB     . ARG   E 1 404 ? 222.720 268.089 218.564 1.00 51.90  ? 416 ARG   B CB     1 
ATOM   4060 C CG     . ARG   E 1 404 ? 223.716 267.155 219.230 1.00 45.43  ? 416 ARG   B CG     1 
ATOM   4061 C CD     . ARG   E 1 404 ? 225.139 267.599 218.960 1.00 56.10  ? 416 ARG   B CD     1 
ATOM   4062 N NE     . ARG   E 1 404 ? 226.125 266.784 219.659 1.00 51.83  ? 416 ARG   B NE     1 
ATOM   4063 C CZ     . ARG   E 1 404 ? 226.123 266.553 220.964 1.00 49.12  ? 416 ARG   B CZ     1 
ATOM   4064 N NH1    . ARG   E 1 404 ? 225.187 267.051 221.754 1.00 51.95  ? 416 ARG   B NH1    1 
ATOM   4065 N NH2    . ARG   E 1 404 ? 227.089 265.807 221.490 1.00 48.19  ? 416 ARG   B NH2    1 
ATOM   4066 N N      . ASN   E 1 405 ? 221.025 266.077 217.299 1.00 50.44  ? 417 ASN   B N      1 
ATOM   4067 C CA     . ASN   E 1 405 ? 220.878 264.727 216.777 1.00 46.00  ? 417 ASN   B CA     1 
ATOM   4068 C C      . ASN   E 1 405 ? 222.253 264.200 216.395 1.00 45.99  ? 417 ASN   B C      1 
ATOM   4069 O O      . ASN   E 1 405 ? 223.044 264.917 215.774 1.00 50.27  ? 417 ASN   B O      1 
ATOM   4070 C CB     . ASN   E 1 405 ? 219.946 264.703 215.565 1.00 42.70  ? 417 ASN   B CB     1 
ATOM   4071 C CG     . ASN   E 1 405 ? 220.253 265.804 214.574 1.00 42.78  ? 417 ASN   B CG     1 
ATOM   4072 O OD1    . ASN   E 1 405 ? 220.005 266.978 214.839 1.00 45.30  ? 417 ASN   B OD1    1 
ATOM   4073 N ND2    . ASN   E 1 405 ? 220.803 265.431 213.425 1.00 37.63  ? 417 ASN   B ND2    1 
ATOM   4074 N N      . LEU   E 1 406 ? 222.539 262.961 216.775 1.00 42.63  ? 418 LEU   B N      1 
ATOM   4075 C CA     . LEU   E 1 406 ? 223.826 262.355 216.462 1.00 47.18  ? 418 LEU   B CA     1 
ATOM   4076 C C      . LEU   E 1 406 ? 223.818 261.824 215.034 1.00 46.77  ? 418 LEU   B C      1 
ATOM   4077 O O      . LEU   E 1 406 ? 223.233 260.768 214.765 1.00 48.57  ? 418 LEU   B O      1 
ATOM   4078 C CB     . LEU   E 1 406 ? 224.144 261.239 217.456 1.00 49.43  ? 418 LEU   B CB     1 
ATOM   4079 C CG     . LEU   E 1 406 ? 223.778 261.554 218.907 1.00 47.52  ? 418 LEU   B CG     1 
ATOM   4080 C CD1    . LEU   E 1 406 ? 224.165 260.412 219.828 1.00 52.69  ? 418 LEU   B CD1    1 
ATOM   4081 C CD2    . LEU   E 1 406 ? 224.434 262.847 219.349 1.00 47.60  ? 418 LEU   B CD2    1 
ATOM   4082 N N      . PRO   E 1 407 ? 224.447 262.522 214.096 1.00 44.43  ? 419 PRO   B N      1 
ATOM   4083 C CA     . PRO   E 1 407 ? 224.417 262.085 212.699 1.00 43.21  ? 419 PRO   B CA     1 
ATOM   4084 C C      . PRO   E 1 407 ? 225.383 260.940 212.432 1.00 44.73  ? 419 PRO   B C      1 
ATOM   4085 O O      . PRO   E 1 407 ? 226.415 260.786 213.086 1.00 47.75  ? 419 PRO   B O      1 
ATOM   4086 C CB     . PRO   E 1 407 ? 224.833 263.341 211.919 1.00 43.12  ? 419 PRO   B CB     1 
ATOM   4087 C CG     . PRO   E 1 407 ? 225.004 264.438 212.945 1.00 41.86  ? 419 PRO   B CG     1 
ATOM   4088 C CD     . PRO   E 1 407 ? 225.195 263.775 214.261 1.00 46.19  ? 419 PRO   B CD     1 
ATOM   4089 N N      . PHE   E 1 408 ? 225.024 260.133 211.437 1.00 43.89  ? 420 PHE   B N      1 
ATOM   4090 C CA     . PHE   E 1 408 ? 225.909 259.094 210.936 1.00 42.58  ? 420 PHE   B CA     1 
ATOM   4091 C C      . PHE   E 1 408 ? 225.596 258.870 209.465 1.00 42.64  ? 420 PHE   B C      1 
ATOM   4092 O O      . PHE   E 1 408 ? 224.510 259.211 208.991 1.00 45.29  ? 420 PHE   B O      1 
ATOM   4093 C CB     . PHE   E 1 408 ? 225.768 257.781 211.716 1.00 44.92  ? 420 PHE   B CB     1 
ATOM   4094 C CG     . PHE   E 1 408 ? 224.349 257.346 211.931 1.00 44.68  ? 420 PHE   B CG     1 
ATOM   4095 C CD1    . PHE   E 1 408 ? 223.636 257.771 213.036 1.00 48.92  ? 420 PHE   B CD1    1 
ATOM   4096 C CD2    . PHE   E 1 408 ? 223.731 256.499 211.029 1.00 43.16  ? 420 PHE   B CD2    1 
ATOM   4097 C CE1    . PHE   E 1 408 ? 222.333 257.364 213.233 1.00 47.53  ? 420 PHE   B CE1    1 
ATOM   4098 C CE2    . PHE   E 1 408 ? 222.431 256.088 211.223 1.00 44.42  ? 420 PHE   B CE2    1 
ATOM   4099 C CZ     . PHE   E 1 408 ? 221.732 256.522 212.325 1.00 44.68  ? 420 PHE   B CZ     1 
ATOM   4100 N N      . ASP   E 1 409 ? 226.564 258.299 208.750 1.00 43.48  ? 421 ASP   B N      1 
ATOM   4101 C CA     . ASP   E 1 409 ? 226.421 258.033 207.319 1.00 43.81  ? 421 ASP   B CA     1 
ATOM   4102 C C      . ASP   E 1 409 ? 225.767 256.665 207.147 1.00 43.92  ? 421 ASP   B C      1 
ATOM   4103 O O      . ASP   E 1 409 ? 226.423 255.631 207.010 1.00 45.00  ? 421 ASP   B O      1 
ATOM   4104 C CB     . ASP   E 1 409 ? 227.773 258.113 206.624 1.00 44.40  ? 421 ASP   B CB     1 
ATOM   4105 C CG     . ASP   E 1 409 ? 227.654 258.098 205.117 1.00 49.68  ? 421 ASP   B CG     1 
ATOM   4106 O OD1    . ASP   E 1 409 ? 226.525 258.241 204.607 1.00 51.75  ? 421 ASP   B OD1    1 
ATOM   4107 O OD2    . ASP   E 1 409 ? 228.692 257.950 204.442 1.00 55.62  ? 421 ASP   B OD2    1 
ATOM   4108 N N      . ARG   E 1 410 ? 224.436 256.670 207.158 1.00 43.37  ? 422 ARG   B N      1 
ATOM   4109 C CA     . ARG   E 1 410 ? 223.671 255.424 207.128 1.00 44.67  ? 422 ARG   B CA     1 
ATOM   4110 C C      . ARG   E 1 410 ? 224.000 254.533 205.938 1.00 47.66  ? 422 ARG   B C      1 
ATOM   4111 O O      . ARG   E 1 410 ? 224.234 253.332 206.144 1.00 48.16  ? 422 ARG   B O      1 
ATOM   4112 C CB     . ARG   E 1 410 ? 222.172 255.748 207.156 1.00 43.97  ? 422 ARG   B CB     1 
ATOM   4113 C CG     . ARG   E 1 410 ? 221.299 254.542 206.887 1.00 47.20  ? 422 ARG   B CG     1 
ATOM   4114 C CD     . ARG   E 1 410 ? 220.011 254.568 207.680 1.00 44.73  ? 422 ARG   B CD     1 
ATOM   4115 N NE     . ARG   E 1 410 ? 219.545 253.214 207.951 1.00 52.08  ? 422 ARG   B NE     1 
ATOM   4116 C CZ     . ARG   E 1 410 ? 219.079 252.387 207.026 1.00 58.57  ? 422 ARG   B CZ     1 
ATOM   4117 N NH1    . ARG   E 1 410 ? 218.993 252.749 205.757 1.00 59.37  ? 422 ARG   B NH1    1 
ATOM   4118 N NH2    . ARG   E 1 410 ? 218.688 251.168 207.383 1.00 65.18  ? 422 ARG   B NH2    1 
ATOM   4119 N N      . PRO   E 1 411 ? 224.017 255.024 204.698 1.00 47.45  ? 423 PRO   B N      1 
ATOM   4120 C CA     . PRO   E 1 411 ? 224.320 254.123 203.574 1.00 46.37  ? 423 PRO   B CA     1 
ATOM   4121 C C      . PRO   E 1 411 ? 225.668 253.436 203.694 1.00 47.56  ? 423 PRO   B C      1 
ATOM   4122 O O      . PRO   E 1 411 ? 225.786 252.251 203.362 1.00 51.48  ? 423 PRO   B O      1 
ATOM   4123 C CB     . PRO   E 1 411 ? 224.264 255.058 202.358 1.00 45.99  ? 423 PRO   B CB     1 
ATOM   4124 C CG     . PRO   E 1 411 ? 223.379 256.175 202.782 1.00 45.76  ? 423 PRO   B CG     1 
ATOM   4125 C CD     . PRO   E 1 411 ? 223.639 256.372 204.244 1.00 47.53  ? 423 PRO   B CD     1 
ATOM   4126 N N      . THR   E 1 412 ? 226.692 254.146 204.167 1.00 45.90  ? 424 THR   B N      1 
ATOM   4127 C CA     . THR   E 1 412 ? 228.029 253.566 204.223 1.00 46.49  ? 424 THR   B CA     1 
ATOM   4128 C C      . THR   E 1 412 ? 228.164 252.554 205.354 1.00 46.09  ? 424 THR   B C      1 
ATOM   4129 O O      . THR   E 1 412 ? 228.784 251.501 205.175 1.00 44.54  ? 424 THR   B O      1 
ATOM   4130 C CB     . THR   E 1 412 ? 229.076 254.669 204.373 1.00 48.37  ? 424 THR   B CB     1 
ATOM   4131 O OG1    . THR   E 1 412 ? 228.714 255.788 203.557 1.00 50.43  ? 424 THR   B OG1    1 
ATOM   4132 C CG2    . THR   E 1 412 ? 230.442 254.163 203.948 1.00 48.57  ? 424 THR   B CG2    1 
ATOM   4133 N N      . ILE   E 1 413 ? 227.600 252.856 206.524 1.00 47.04  ? 425 ILE   B N      1 
ATOM   4134 C CA     . ILE   E 1 413 ? 227.741 251.953 207.662 1.00 47.55  ? 425 ILE   B CA     1 
ATOM   4135 C C      . ILE   E 1 413 ? 227.010 250.643 207.402 1.00 48.31  ? 425 ILE   B C      1 
ATOM   4136 O O      . ILE   E 1 413 ? 227.546 249.558 207.652 1.00 52.72  ? 425 ILE   B O      1 
ATOM   4137 C CB     . ILE   E 1 413 ? 227.245 252.632 208.950 1.00 48.46  ? 425 ILE   B CB     1 
ATOM   4138 C CG1    . ILE   E 1 413 ? 227.868 254.019 209.093 1.00 49.36  ? 425 ILE   B CG1    1 
ATOM   4139 C CG2    . ILE   E 1 413 ? 227.578 251.780 210.160 1.00 48.81  ? 425 ILE   B CG2    1 
ATOM   4140 C CD1    . ILE   E 1 413 ? 227.023 254.981 209.890 1.00 49.69  ? 425 ILE   B CD1    1 
ATOM   4141 N N      . MET   E 1 414 ? 225.778 250.719 206.900 1.00 48.58  ? 426 MET   B N      1 
ATOM   4142 C CA     . MET   E 1 414 ? 225.000 249.519 206.621 1.00 51.49  ? 426 MET   B CA     1 
ATOM   4143 C C      . MET   E 1 414 ? 225.396 248.841 205.319 1.00 52.96  ? 426 MET   B C      1 
ATOM   4144 O O      . MET   E 1 414 ? 224.983 247.700 205.086 1.00 55.49  ? 426 MET   B O      1 
ATOM   4145 C CB     . MET   E 1 414 ? 223.509 249.853 206.588 1.00 52.87  ? 426 MET   B CB     1 
ATOM   4146 C CG     . MET   E 1 414 ? 223.055 250.727 207.736 1.00 53.10  ? 426 MET   B CG     1 
ATOM   4147 S SD     . MET   E 1 414 ? 222.991 249.788 209.267 1.00 66.79  ? 426 MET   B SD     1 
ATOM   4148 C CE     . MET   E 1 414 ? 221.228 249.720 209.535 1.00 66.64  ? 426 MET   B CE     1 
ATOM   4149 N N      . ALA   E 1 415 ? 226.182 249.505 204.471 1.00 51.74  ? 427 ALA   B N      1 
ATOM   4150 C CA     . ALA   E 1 415 ? 226.620 248.877 203.231 1.00 50.80  ? 427 ALA   B CA     1 
ATOM   4151 C C      . ALA   E 1 415 ? 227.490 247.659 203.510 1.00 56.27  ? 427 ALA   B C      1 
ATOM   4152 O O      . ALA   E 1 415 ? 227.389 246.642 202.815 1.00 63.67  ? 427 ALA   B O      1 
ATOM   4153 C CB     . ALA   E 1 415 ? 227.368 249.887 202.363 1.00 52.98  ? 427 ALA   B CB     1 
ATOM   4154 N N      . ALA   E 1 416 ? 228.347 247.739 204.524 1.00 53.13  ? 428 ALA   B N      1 
ATOM   4155 C CA     . ALA   E 1 416 ? 229.252 246.637 204.846 1.00 56.60  ? 428 ALA   B CA     1 
ATOM   4156 C C      . ALA   E 1 416 ? 228.587 245.619 205.764 1.00 60.09  ? 428 ALA   B C      1 
ATOM   4157 O O      . ALA   E 1 416 ? 229.124 245.244 206.802 1.00 60.86  ? 428 ALA   B O      1 
ATOM   4158 C CB     . ALA   E 1 416 ? 230.532 247.180 205.469 1.00 53.32  ? 428 ALA   B CB     1 
ATOM   4159 N N      . PHE   E 1 417 ? 227.416 245.143 205.356 1.00 64.30  ? 429 PHE   B N      1 
ATOM   4160 C CA     . PHE   E 1 417 ? 226.648 244.189 206.144 1.00 63.29  ? 429 PHE   B CA     1 
ATOM   4161 C C      . PHE   E 1 417 ? 225.966 243.163 205.246 1.00 61.91  ? 429 PHE   B C      1 
ATOM   4162 O O      . PHE   E 1 417 ? 226.007 243.270 204.021 1.00 53.00  ? 429 PHE   B O      1 
ATOM   4163 C CB     . PHE   E 1 417 ? 225.607 244.915 206.994 1.00 57.52  ? 429 PHE   B CB     1 
ATOM   4164 C CG     . PHE   E 1 417 ? 226.101 245.306 208.354 1.00 62.17  ? 429 PHE   B CG     1 
ATOM   4165 C CD1    . PHE   E 1 417 ? 225.372 246.174 209.145 1.00 68.42  ? 429 PHE   B CD1    1 
ATOM   4166 C CD2    . PHE   E 1 417 ? 227.288 244.800 208.844 1.00 60.47  ? 429 PHE   B CD2    1 
ATOM   4167 C CE1    . PHE   E 1 417 ? 225.824 246.533 210.395 1.00 64.36  ? 429 PHE   B CE1    1 
ATOM   4168 C CE2    . PHE   E 1 417 ? 227.743 245.157 210.092 1.00 61.98  ? 429 PHE   B CE2    1 
ATOM   4169 C CZ     . PHE   E 1 417 ? 227.010 246.024 210.871 1.00 59.86  ? 429 PHE   B CZ     1 
ATOM   4170 N N      . MET   E 1 428 ? 232.658 240.406 193.483 1.00 56.83  ? 440 MET   B N      1 
ATOM   4171 C CA     . MET   E 1 428 ? 232.913 239.165 192.762 1.00 56.81  ? 440 MET   B CA     1 
ATOM   4172 C C      . MET   E 1 428 ? 233.928 239.370 191.627 1.00 57.23  ? 440 MET   B C      1 
ATOM   4173 O O      . MET   E 1 428 ? 235.117 239.538 191.891 1.00 62.22  ? 440 MET   B O      1 
ATOM   4174 C CB     . MET   E 1 428 ? 231.582 238.564 192.266 1.00 59.70  ? 440 MET   B CB     1 
ATOM   4175 C CG     . MET   E 1 428 ? 230.879 239.276 191.115 1.00 58.04  ? 440 MET   B CG     1 
ATOM   4176 S SD     . MET   E 1 428 ? 229.954 238.132 190.071 1.00 66.31  ? 440 MET   B SD     1 
ATOM   4177 C CE     . MET   E 1 428 ? 230.987 238.076 188.611 1.00 56.22  ? 440 MET   B CE     1 
ATOM   4178 N N      . ARG   E 1 429 ? 233.483 239.361 190.387 1.00 56.08  ? 441 ARG   B N      1 
ATOM   4179 C CA     . ARG   E 1 429 ? 234.404 239.458 189.262 1.00 51.34  ? 441 ARG   B CA     1 
ATOM   4180 C C      . ARG   E 1 429 ? 234.170 240.691 188.408 1.00 53.40  ? 441 ARG   B C      1 
ATOM   4181 O O      . ARG   E 1 429 ? 235.137 241.323 187.978 1.00 55.46  ? 441 ARG   B O      1 
ATOM   4182 C CB     . ARG   E 1 429 ? 234.294 238.194 188.401 1.00 50.92  ? 441 ARG   B CB     1 
ATOM   4183 C CG     . ARG   E 1 429 ? 235.537 237.876 187.600 1.00 50.07  ? 441 ARG   B CG     1 
ATOM   4184 C CD     . ARG   E 1 429 ? 235.271 236.751 186.626 1.00 52.65  ? 441 ARG   B CD     1 
ATOM   4185 N NE     . ARG   E 1 429 ? 235.304 235.456 187.294 1.00 57.41  ? 441 ARG   B NE     1 
ATOM   4186 C CZ     . ARG   E 1 429 ? 235.969 234.400 186.849 1.00 62.51  ? 441 ARG   B CZ     1 
ATOM   4187 N NH1    . ARG   E 1 429 ? 236.671 234.447 185.728 1.00 65.21  ? 441 ARG   B NH1    1 
ATOM   4188 N NH2    . ARG   E 1 429 ? 235.925 233.267 187.542 1.00 53.51  ? 441 ARG   B NH2    1 
ATOM   4189 N N      . THR   E 1 430 ? 232.912 241.057 188.157 1.00 56.05  ? 442 THR   B N      1 
ATOM   4190 C CA     . THR   E 1 430 ? 232.643 242.286 187.422 1.00 55.34  ? 442 THR   B CA     1 
ATOM   4191 C C      . THR   E 1 430 ? 233.090 243.510 188.208 1.00 55.22  ? 442 THR   B C      1 
ATOM   4192 O O      . THR   E 1 430 ? 233.566 244.486 187.618 1.00 55.48  ? 442 THR   B O      1 
ATOM   4193 C CB     . THR   E 1 430 ? 231.157 242.388 187.083 1.00 59.64  ? 442 THR   B CB     1 
ATOM   4194 O OG1    . THR   E 1 430 ? 230.383 241.868 188.170 1.00 66.08  ? 442 THR   B OG1    1 
ATOM   4195 C CG2    . THR   E 1 430 ? 230.847 241.597 185.824 1.00 62.33  ? 442 THR   B CG2    1 
ATOM   4196 N N      . GLU   E 1 431 ? 232.947 243.479 189.534 1.00 54.44  ? 443 GLU   B N      1 
ATOM   4197 C CA     . GLU   E 1 431 ? 233.405 244.598 190.348 1.00 55.60  ? 443 GLU   B CA     1 
ATOM   4198 C C      . GLU   E 1 431 ? 234.917 244.758 190.261 1.00 57.96  ? 443 GLU   B C      1 
ATOM   4199 O O      . GLU   E 1 431 ? 235.427 245.882 190.186 1.00 61.05  ? 443 GLU   B O      1 
ATOM   4200 C CB     . GLU   E 1 431 ? 232.971 244.406 191.799 1.00 56.82  ? 443 GLU   B CB     1 
ATOM   4201 C CG     . GLU   E 1 431 ? 233.666 245.338 192.773 1.00 61.28  ? 443 GLU   B CG     1 
ATOM   4202 C CD     . GLU   E 1 431 ? 233.031 246.709 192.815 1.00 70.12  ? 443 GLU   B CD     1 
ATOM   4203 O OE1    . GLU   E 1 431 ? 232.372 247.090 191.826 1.00 74.45  ? 443 GLU   B OE1    1 
ATOM   4204 O OE2    . GLU   E 1 431 ? 233.189 247.408 193.837 1.00 73.41  ? 443 GLU   B OE2    1 
ATOM   4205 N N      . ILE   E 1 432 ? 235.650 243.645 190.273 1.00 56.67  ? 444 ILE   B N      1 
ATOM   4206 C CA     . ILE   E 1 432 ? 237.106 243.716 190.206 1.00 52.88  ? 444 ILE   B CA     1 
ATOM   4207 C C      . ILE   E 1 432 ? 237.550 244.324 188.883 1.00 52.53  ? 444 ILE   B C      1 
ATOM   4208 O O      . ILE   E 1 432 ? 238.429 245.192 188.847 1.00 52.34  ? 444 ILE   B O      1 
ATOM   4209 C CB     . ILE   E 1 432 ? 237.719 242.322 190.420 1.00 50.83  ? 444 ILE   B CB     1 
ATOM   4210 C CG1    . ILE   E 1 432 ? 237.812 242.001 191.910 1.00 45.90  ? 444 ILE   B CG1    1 
ATOM   4211 C CG2    . ILE   E 1 432 ? 239.098 242.250 189.793 1.00 53.97  ? 444 ILE   B CG2    1 
ATOM   4212 C CD1    . ILE   E 1 432 ? 238.659 240.792 192.213 1.00 44.70  ? 444 ILE   B CD1    1 
ATOM   4213 N N      . ILE   E 1 433 ? 236.949 243.884 187.775 1.00 50.26  ? 445 ILE   B N      1 
ATOM   4214 C CA     . ILE   E 1 433 ? 237.319 244.418 186.469 1.00 51.76  ? 445 ILE   B CA     1 
ATOM   4215 C C      . ILE   E 1 433 ? 237.041 245.913 186.407 1.00 53.20  ? 445 ILE   B C      1 
ATOM   4216 O O      . ILE   E 1 433 ? 237.818 246.682 185.830 1.00 55.54  ? 445 ILE   B O      1 
ATOM   4217 C CB     . ILE   E 1 433 ? 236.585 243.658 185.350 1.00 50.00  ? 445 ILE   B CB     1 
ATOM   4218 C CG1    . ILE   E 1 433 ? 236.624 242.155 185.613 1.00 49.30  ? 445 ILE   B CG1    1 
ATOM   4219 C CG2    . ILE   E 1 433 ? 237.196 243.977 184.000 1.00 54.57  ? 445 ILE   B CG2    1 
ATOM   4220 C CD1    . ILE   E 1 433 ? 236.321 241.322 184.393 1.00 51.30  ? 445 ILE   B CD1    1 
ATOM   4221 N N      . ARG   E 1 434 ? 235.928 246.349 187.000 1.00 53.32  ? 446 ARG   B N      1 
ATOM   4222 C CA     . ARG   E 1 434 ? 235.623 247.774 187.033 1.00 53.98  ? 446 ARG   B CA     1 
ATOM   4223 C C      . ARG   E 1 434 ? 236.672 248.553 187.812 1.00 57.65  ? 446 ARG   B C      1 
ATOM   4224 O O      . ARG   E 1 434 ? 237.034 249.669 187.423 1.00 61.24  ? 446 ARG   B O      1 
ATOM   4225 C CB     . ARG   E 1 434 ? 234.241 248.002 187.639 1.00 55.07  ? 446 ARG   B CB     1 
ATOM   4226 C CG     . ARG   E 1 434 ? 233.782 249.445 187.583 1.00 56.81  ? 446 ARG   B CG     1 
ATOM   4227 C CD     . ARG   E 1 434 ? 232.517 249.654 188.391 1.00 59.53  ? 446 ARG   B CD     1 
ATOM   4228 N NE     . ARG   E 1 434 ? 232.723 249.387 189.808 1.00 60.27  ? 446 ARG   B NE     1 
ATOM   4229 C CZ     . ARG   E 1 434 ? 233.202 250.270 190.672 1.00 63.60  ? 446 ARG   B CZ     1 
ATOM   4230 N NH1    . ARG   E 1 434 ? 233.550 251.488 190.294 1.00 62.07  ? 446 ARG   B NH1    1 
ATOM   4231 N NH2    . ARG   E 1 434 ? 233.337 249.921 191.948 1.00 65.10  ? 446 ARG   B NH2    1 
ATOM   4232 N N      . LEU   E 1 435 ? 237.168 247.987 188.913 1.00 54.05  ? 447 LEU   B N      1 
ATOM   4233 C CA     . LEU   E 1 435 ? 238.173 248.679 189.712 1.00 51.64  ? 447 LEU   B CA     1 
ATOM   4234 C C      . LEU   E 1 435 ? 239.451 248.921 188.918 1.00 51.07  ? 447 LEU   B C      1 
ATOM   4235 O O      . LEU   E 1 435 ? 240.036 250.007 188.996 1.00 49.92  ? 447 LEU   B O      1 
ATOM   4236 C CB     . LEU   E 1 435 ? 238.473 247.879 190.978 1.00 51.36  ? 447 LEU   B CB     1 
ATOM   4237 C CG     . LEU   E 1 435 ? 237.482 248.036 192.128 1.00 51.88  ? 447 LEU   B CG     1 
ATOM   4238 C CD1    . LEU   E 1 435 ? 237.576 246.856 193.074 1.00 57.90  ? 447 LEU   B CD1    1 
ATOM   4239 C CD2    . LEU   E 1 435 ? 237.749 249.334 192.866 1.00 42.56  ? 447 LEU   B CD2    1 
ATOM   4240 N N      . MET   E 1 436 ? 239.906 247.924 188.154 1.00 51.90  ? 448 MET   B N      1 
ATOM   4241 C CA     . MET   E 1 436 ? 241.177 248.077 187.453 1.00 51.84  ? 448 MET   B CA     1 
ATOM   4242 C C      . MET   E 1 436 ? 241.055 248.990 186.240 1.00 53.74  ? 448 MET   B C      1 
ATOM   4243 O O      . MET   E 1 436 ? 242.039 249.631 185.856 1.00 59.28  ? 448 MET   B O      1 
ATOM   4244 C CB     . MET   E 1 436 ? 241.738 246.716 187.040 1.00 52.71  ? 448 MET   B CB     1 
ATOM   4245 C CG     . MET   E 1 436 ? 241.109 245.528 187.732 1.00 51.63  ? 448 MET   B CG     1 
ATOM   4246 S SD     . MET   E 1 436 ? 241.988 244.003 187.343 1.00 57.14  ? 448 MET   B SD     1 
ATOM   4247 C CE     . MET   E 1 436 ? 241.749 243.915 185.575 1.00 46.59  ? 448 MET   B CE     1 
ATOM   4248 N N      . GLU   E 1 437 ? 239.876 249.062 185.620 1.00 52.45  ? 449 GLU   B N      1 
ATOM   4249 C CA     . GLU   E 1 437 ? 239.711 249.988 184.504 1.00 58.03  ? 449 GLU   B CA     1 
ATOM   4250 C C      . GLU   E 1 437 ? 239.830 251.436 184.958 1.00 59.25  ? 449 GLU   B C      1 
ATOM   4251 O O      . GLU   E 1 437 ? 240.375 252.271 184.227 1.00 64.94  ? 449 GLU   B O      1 
ATOM   4252 C CB     . GLU   E 1 437 ? 238.374 249.755 183.804 1.00 60.04  ? 449 GLU   B CB     1 
ATOM   4253 C CG     . GLU   E 1 437 ? 238.374 248.558 182.871 1.00 71.82  ? 449 GLU   B CG     1 
ATOM   4254 C CD     . GLU   E 1 437 ? 236.981 248.029 182.596 1.00 91.95  ? 449 GLU   B CD     1 
ATOM   4255 O OE1    . GLU   E 1 437 ? 236.272 247.686 183.566 1.00 87.18  ? 449 GLU   B OE1    1 
ATOM   4256 O OE2    . GLU   E 1 437 ? 236.596 247.954 181.411 1.00 101.75 ? 449 GLU   B OE2    1 
ATOM   4257 N N      . SER   E 1 438 ? 239.334 251.755 186.153 1.00 52.47  ? 450 SER   B N      1 
ATOM   4258 C CA     . SER   E 1 438 ? 239.486 253.113 186.665 1.00 52.14  ? 450 SER   B CA     1 
ATOM   4259 C C      . SER   E 1 438 ? 240.950 253.444 186.922 1.00 54.44  ? 450 SER   B C      1 
ATOM   4260 O O      . SER   E 1 438 ? 241.377 254.588 186.726 1.00 60.12  ? 450 SER   B O      1 
ATOM   4261 C CB     . SER   E 1 438 ? 238.663 253.290 187.940 1.00 53.45  ? 450 SER   B CB     1 
ATOM   4262 O OG     . SER   E 1 438 ? 239.381 252.844 189.075 1.00 58.20  ? 450 SER   B OG     1 
ATOM   4263 N N      . ALA   E 1 439 ? 241.733 252.462 187.359 1.00 51.51  ? 451 ALA   B N      1 
ATOM   4264 C CA     . ALA   E 1 439 ? 243.136 252.700 187.662 1.00 48.57  ? 451 ALA   B CA     1 
ATOM   4265 C C      . ALA   E 1 439 ? 243.927 252.969 186.389 1.00 52.78  ? 451 ALA   B C      1 
ATOM   4266 O O      . ALA   E 1 439 ? 243.698 252.345 185.350 1.00 56.45  ? 451 ALA   B O      1 
ATOM   4267 C CB     . ALA   E 1 439 ? 243.728 251.504 188.404 1.00 46.49  ? 451 ALA   B CB     1 
ATOM   4268 N N      . ARG   E 1 440 ? 244.865 253.906 186.475 1.00 51.39  ? 452 ARG   B N      1 
ATOM   4269 C CA     . ARG   E 1 440 ? 245.726 254.262 185.361 1.00 54.08  ? 452 ARG   B CA     1 
ATOM   4270 C C      . ARG   E 1 440 ? 247.175 254.275 185.817 1.00 58.17  ? 452 ARG   B C      1 
ATOM   4271 O O      . ARG   E 1 440 ? 247.456 254.485 187.000 1.00 59.88  ? 452 ARG   B O      1 
ATOM   4272 C CB     . ARG   E 1 440 ? 245.359 255.638 184.791 1.00 53.62  ? 452 ARG   B CB     1 
ATOM   4273 C CG     . ARG   E 1 440 ? 243.870 255.888 184.693 1.00 53.67  ? 452 ARG   B CG     1 
ATOM   4274 C CD     . ARG   E 1 440 ? 243.509 256.502 183.358 1.00 54.10  ? 452 ARG   B CD     1 
ATOM   4275 N NE     . ARG   E 1 440 ? 243.162 255.488 182.371 1.00 53.71  ? 452 ARG   B NE     1 
ATOM   4276 C CZ     . ARG   E 1 440 ? 241.980 254.895 182.294 1.00 54.83  ? 452 ARG   B CZ     1 
ATOM   4277 N NH1    . ARG   E 1 440 ? 241.009 255.178 183.144 1.00 52.48  ? 452 ARG   B NH1    1 
ATOM   4278 N NH2    . ARG   E 1 440 ? 241.768 253.994 181.340 1.00 57.76  ? 452 ARG   B NH2    1 
ATOM   4279 N N      . PRO   E 1 441 ? 248.122 254.060 184.896 1.00 60.65  ? 453 PRO   B N      1 
ATOM   4280 C CA     . PRO   E 1 441 ? 249.547 254.041 185.253 1.00 61.90  ? 453 PRO   B CA     1 
ATOM   4281 C C      . PRO   E 1 441 ? 250.131 255.440 185.438 1.00 66.06  ? 453 PRO   B C      1 
ATOM   4282 O O      . PRO   E 1 441 ? 251.228 255.743 184.965 1.00 73.61  ? 453 PRO   B O      1 
ATOM   4283 C CB     . PRO   E 1 441 ? 250.191 253.311 184.071 1.00 58.24  ? 453 PRO   B CB     1 
ATOM   4284 C CG     . PRO   E 1 441 ? 249.120 253.086 183.051 1.00 57.22  ? 453 PRO   B CG     1 
ATOM   4285 C CD     . PRO   E 1 441 ? 247.895 253.811 183.466 1.00 59.93  ? 453 PRO   B CD     1 
ATOM   4286 N N      . GLU   E 1 442 ? 249.395 256.294 186.145 1.00 60.72  ? 454 GLU   B N      1 
ATOM   4287 C CA     . GLU   E 1 442 ? 249.862 257.628 186.495 1.00 58.45  ? 454 GLU   B CA     1 
ATOM   4288 C C      . GLU   E 1 442 ? 249.533 258.025 187.922 1.00 59.28  ? 454 GLU   B C      1 
ATOM   4289 O O      . GLU   E 1 442 ? 250.035 259.056 188.379 1.00 63.19  ? 454 GLU   B O      1 
ATOM   4290 C CB     . GLU   E 1 442 ? 249.272 258.682 185.546 1.00 57.48  ? 454 GLU   B CB     1 
ATOM   4291 C CG     . GLU   E 1 442 ? 248.889 258.159 184.178 1.00 58.86  ? 454 GLU   B CG     1 
ATOM   4292 C CD     . GLU   E 1 442 ? 250.090 257.949 183.285 1.00 66.08  ? 454 GLU   B CD     1 
ATOM   4293 O OE1    . GLU   E 1 442 ? 251.227 258.017 183.796 1.00 68.56  ? 454 GLU   B OE1    1 
ATOM   4294 O OE2    . GLU   E 1 442 ? 249.900 257.720 182.074 1.00 68.31  ? 454 GLU   B OE2    1 
ATOM   4295 N N      . ASP   E 1 443 ? 248.709 257.263 188.636 1.00 57.64  ? 455 ASP   B N      1 
ATOM   4296 C CA     . ASP   E 1 443 ? 248.348 257.624 189.998 1.00 55.39  ? 455 ASP   B CA     1 
ATOM   4297 C C      . ASP   E 1 443 ? 249.593 257.711 190.867 1.00 57.42  ? 455 ASP   B C      1 
ATOM   4298 O O      . ASP   E 1 443 ? 250.454 256.827 190.832 1.00 63.07  ? 455 ASP   B O      1 
ATOM   4299 C CB     . ASP   E 1 443 ? 247.372 256.599 190.572 1.00 54.90  ? 455 ASP   B CB     1 
ATOM   4300 C CG     . ASP   E 1 443 ? 246.168 256.385 189.684 1.00 62.85  ? 455 ASP   B CG     1 
ATOM   4301 O OD1    . ASP   E 1 443 ? 245.196 255.750 190.141 1.00 65.00  ? 455 ASP   B OD1    1 
ATOM   4302 O OD2    . ASP   E 1 443 ? 246.191 256.854 188.529 1.00 67.91  ? 455 ASP   B OD2    1 
ATOM   4303 N N      . VAL   E 1 444 ? 249.689 258.778 191.644 1.00 51.73  ? 456 VAL   B N      1 
ATOM   4304 C CA     . VAL   E 1 444 ? 250.801 258.961 192.564 1.00 51.28  ? 456 VAL   B CA     1 
ATOM   4305 C C      . VAL   E 1 444 ? 250.508 258.182 193.837 1.00 52.49  ? 456 VAL   B C      1 
ATOM   4306 O O      . VAL   E 1 444 ? 249.477 258.393 194.486 1.00 52.92  ? 456 VAL   B O      1 
ATOM   4307 C CB     . VAL   E 1 444 ? 251.027 260.450 192.866 1.00 52.59  ? 456 VAL   B CB     1 
ATOM   4308 C CG1    . VAL   E 1 444 ? 251.862 260.612 194.122 1.00 53.27  ? 456 VAL   B CG1    1 
ATOM   4309 C CG2    . VAL   E 1 444 ? 251.700 261.126 191.686 1.00 50.66  ? 456 VAL   B CG2    1 
ATOM   4310 N N      . SER   E 1 445 ? 251.407 257.273 194.187 1.00 50.28  ? 457 SER   B N      1 
ATOM   4311 C CA     . SER   E 1 445 ? 251.319 256.507 195.417 1.00 48.96  ? 457 SER   B CA     1 
ATOM   4312 C C      . SER   E 1 445 ? 252.456 256.908 196.345 1.00 48.93  ? 457 SER   B C      1 
ATOM   4313 O O      . SER   E 1 445 ? 253.490 257.421 195.911 1.00 49.03  ? 457 SER   B O      1 
ATOM   4314 C CB     . SER   E 1 445 ? 251.367 255.003 195.133 1.00 49.47  ? 457 SER   B CB     1 
ATOM   4315 O OG     . SER   E 1 445 ? 250.062 254.467 195.017 1.00 56.38  ? 457 SER   B OG     1 
ATOM   4316 N N      . PHE   E 1 446 ? 252.255 256.662 197.636 1.00 47.28  ? 458 PHE   B N      1 
ATOM   4317 C CA     . PHE   E 1 446 ? 253.214 257.066 198.658 1.00 48.74  ? 458 PHE   B CA     1 
ATOM   4318 C C      . PHE   E 1 446 ? 253.463 258.571 198.594 1.00 48.93  ? 458 PHE   B C      1 
ATOM   4319 O O      . PHE   E 1 446 ? 254.601 259.042 198.578 1.00 52.74  ? 458 PHE   B O      1 
ATOM   4320 C CB     . PHE   E 1 446 ? 254.523 256.288 198.520 1.00 48.70  ? 458 PHE   B CB     1 
ATOM   4321 C CG     . PHE   E 1 446 ? 254.341 254.802 198.464 1.00 46.59  ? 458 PHE   B CG     1 
ATOM   4322 C CD1    . PHE   E 1 446 ? 254.036 254.086 199.606 1.00 47.19  ? 458 PHE   B CD1    1 
ATOM   4323 C CD2    . PHE   E 1 446 ? 254.483 254.118 197.271 1.00 45.28  ? 458 PHE   B CD2    1 
ATOM   4324 C CE1    . PHE   E 1 446 ? 253.870 252.719 199.559 1.00 46.43  ? 458 PHE   B CE1    1 
ATOM   4325 C CE2    . PHE   E 1 446 ? 254.318 252.752 197.219 1.00 45.75  ? 458 PHE   B CE2    1 
ATOM   4326 C CZ     . PHE   E 1 446 ? 254.011 252.052 198.364 1.00 47.55  ? 458 PHE   B CZ     1 
ATOM   4327 N N      . GLN   E 1 447 ? 252.372 259.328 198.549 1.00 48.38  ? 459 GLN   B N      1 
ATOM   4328 C CA     . GLN   E 1 447 ? 252.464 260.777 198.445 1.00 48.56  ? 459 GLN   B CA     1 
ATOM   4329 C C      . GLN   E 1 447 ? 253.243 261.355 199.619 1.00 50.74  ? 459 GLN   B C      1 
ATOM   4330 O O      . GLN   E 1 447 ? 253.003 261.000 200.777 1.00 50.56  ? 459 GLN   B O      1 
ATOM   4331 C CB     . GLN   E 1 447 ? 251.064 261.385 198.389 1.00 49.27  ? 459 GLN   B CB     1 
ATOM   4332 C CG     . GLN   E 1 447 ? 251.040 262.879 198.136 1.00 51.28  ? 459 GLN   B CG     1 
ATOM   4333 C CD     . GLN   E 1 447 ? 249.641 263.407 197.920 1.00 54.38  ? 459 GLN   B CD     1 
ATOM   4334 O OE1    . GLN   E 1 447 ? 248.680 262.643 197.868 1.00 58.11  ? 459 GLN   B OE1    1 
ATOM   4335 N NE2    . GLN   E 1 447 ? 249.518 264.721 197.793 1.00 56.24  ? 459 GLN   B NE2    1 
ATOM   4336 N N      . GLY   E 1 448 ? 254.180 262.249 199.316 1.00 49.80  ? 460 GLY   B N      1 
ATOM   4337 C CA     . GLY   E 1 448 ? 254.946 262.930 200.335 1.00 49.35  ? 460 GLY   B CA     1 
ATOM   4338 C C      . GLY   E 1 448 ? 256.082 262.135 200.934 1.00 52.61  ? 460 GLY   B C      1 
ATOM   4339 O O      . GLY   E 1 448 ? 256.752 262.637 201.844 1.00 59.80  ? 460 GLY   B O      1 
ATOM   4340 N N      . ARG   E 1 449 ? 256.323 260.917 200.461 1.00 50.34  ? 461 ARG   B N      1 
ATOM   4341 C CA     . ARG   E 1 449 ? 257.370 260.054 200.990 1.00 49.47  ? 461 ARG   B CA     1 
ATOM   4342 C C      . ARG   E 1 449 ? 258.509 260.002 199.983 1.00 51.70  ? 461 ARG   B C      1 
ATOM   4343 O O      . ARG   E 1 449 ? 258.277 259.764 198.793 1.00 57.24  ? 461 ARG   B O      1 
ATOM   4344 C CB     . ARG   E 1 449 ? 256.829 258.655 201.274 1.00 47.72  ? 461 ARG   B CB     1 
ATOM   4345 C CG     . ARG   E 1 449 ? 256.268 258.481 202.671 1.00 46.65  ? 461 ARG   B CG     1 
ATOM   4346 C CD     . ARG   E 1 449 ? 254.833 257.994 202.621 1.00 52.46  ? 461 ARG   B CD     1 
ATOM   4347 N NE     . ARG   E 1 449 ? 254.348 257.570 203.928 1.00 58.38  ? 461 ARG   B NE     1 
ATOM   4348 C CZ     . ARG   E 1 449 ? 254.154 258.383 204.956 1.00 56.48  ? 461 ARG   B CZ     1 
ATOM   4349 N NH1    . ARG   E 1 449 ? 254.400 259.679 204.868 1.00 51.33  ? 461 ARG   B NH1    1 
ATOM   4350 N NH2    . ARG   E 1 449 ? 253.704 257.882 206.103 1.00 60.37  ? 461 ARG   B NH2    1 
ATOM   4351 N N      . GLY   E 1 450 ? 259.729 260.235 200.455 1.00 47.89  ? 462 GLY   B N      1 
ATOM   4352 C CA     . GLY   E 1 450 ? 260.871 260.282 199.566 1.00 48.10  ? 462 GLY   B CA     1 
ATOM   4353 C C      . GLY   E 1 450 ? 262.035 259.416 199.995 1.00 48.42  ? 462 GLY   B C      1 
ATOM   4354 O O      . GLY   E 1 450 ? 261.857 258.407 200.682 1.00 53.62  ? 462 GLY   B O      1 
ATOM   4355 N N      . VAL   E 1 451 ? 263.240 259.815 199.597 1.00 46.93  ? 463 VAL   B N      1 
ATOM   4356 C CA     . VAL   E 1 451 ? 264.461 259.069 199.871 1.00 44.12  ? 463 VAL   B CA     1 
ATOM   4357 C C      . VAL   E 1 451 ? 265.377 259.957 200.697 1.00 46.54  ? 463 VAL   B C      1 
ATOM   4358 O O      . VAL   E 1 451 ? 265.526 261.147 200.404 1.00 52.87  ? 463 VAL   B O      1 
ATOM   4359 C CB     . VAL   E 1 451 ? 265.161 258.617 198.575 1.00 46.31  ? 463 VAL   B CB     1 
ATOM   4360 C CG1    . VAL   E 1 451 ? 264.141 258.095 197.580 1.00 51.21  ? 463 VAL   B CG1    1 
ATOM   4361 C CG2    . VAL   E 1 451 ? 265.959 259.757 197.973 1.00 44.88  ? 463 VAL   B CG2    1 
ATOM   4362 N N      . PHE   E 1 452 ? 265.974 259.385 201.735 1.00 45.87  ? 464 PHE   B N      1 
ATOM   4363 C CA     . PHE   E 1 452 ? 266.783 260.140 202.673 1.00 44.91  ? 464 PHE   B CA     1 
ATOM   4364 C C      . PHE   E 1 452 ? 268.262 259.989 202.337 1.00 45.82  ? 464 PHE   B C      1 
ATOM   4365 O O      . PHE   E 1 452 ? 268.657 259.230 201.449 1.00 49.26  ? 464 PHE   B O      1 
ATOM   4366 C CB     . PHE   E 1 452 ? 266.504 259.692 204.110 1.00 46.31  ? 464 PHE   B CB     1 
ATOM   4367 C CG     . PHE   E 1 452 ? 265.054 259.433 204.400 1.00 45.67  ? 464 PHE   B CG     1 
ATOM   4368 C CD1    . PHE   E 1 452 ? 264.329 260.315 205.177 1.00 49.22  ? 464 PHE   B CD1    1 
ATOM   4369 C CD2    . PHE   E 1 452 ? 264.423 258.298 203.924 1.00 46.15  ? 464 PHE   B CD2    1 
ATOM   4370 C CE1    . PHE   E 1 452 ? 263.001 260.083 205.453 1.00 51.62  ? 464 PHE   B CE1    1 
ATOM   4371 C CE2    . PHE   E 1 452 ? 263.095 258.063 204.197 1.00 49.09  ? 464 PHE   B CE2    1 
ATOM   4372 C CZ     . PHE   E 1 452 ? 262.385 258.956 204.965 1.00 51.96  ? 464 PHE   B CZ     1 
ATOM   4373 N N      . GLU   E 1 453 ? 269.091 260.719 203.072 1.00 44.54  ? 465 GLU   B N      1 
ATOM   4374 C CA     . GLU   E 1 453 ? 270.534 260.662 202.928 1.00 46.30  ? 465 GLU   B CA     1 
ATOM   4375 C C      . GLU   E 1 453 ? 271.122 259.754 203.997 1.00 47.98  ? 465 GLU   B C      1 
ATOM   4376 O O      . GLU   E 1 453 ? 270.548 259.570 205.073 1.00 48.05  ? 465 GLU   B O      1 
ATOM   4377 C CB     . GLU   E 1 453 ? 271.153 262.059 203.031 1.00 47.36  ? 465 GLU   B CB     1 
ATOM   4378 C CG     . GLU   E 1 453 ? 270.795 262.982 201.887 1.00 50.07  ? 465 GLU   B CG     1 
ATOM   4379 C CD     . GLU   E 1 453 ? 271.987 263.305 201.014 1.00 62.67  ? 465 GLU   B CD     1 
ATOM   4380 O OE1    . GLU   E 1 453 ? 272.975 262.544 201.052 1.00 63.75  ? 465 GLU   B OE1    1 
ATOM   4381 O OE2    . GLU   E 1 453 ? 271.939 264.321 200.292 1.00 71.40  ? 465 GLU   B OE2    1 
ATOM   4382 N N      . LEU   E 1 454 ? 272.285 259.181 203.683 1.00 49.01  ? 466 LEU   B N      1 
ATOM   4383 C CA     . LEU   E 1 454 ? 272.932 258.277 204.625 1.00 46.10  ? 466 LEU   B CA     1 
ATOM   4384 C C      . LEU   E 1 454 ? 273.266 258.980 205.932 1.00 51.65  ? 466 LEU   B C      1 
ATOM   4385 O O      . LEU   E 1 454 ? 273.274 258.346 206.993 1.00 61.16  ? 466 LEU   B O      1 
ATOM   4386 C CB     . LEU   E 1 454 ? 274.190 257.679 203.999 1.00 43.64  ? 466 LEU   B CB     1 
ATOM   4387 C CG     . LEU   E 1 454 ? 274.003 256.353 203.262 1.00 44.55  ? 466 LEU   B CG     1 
ATOM   4388 C CD1    . LEU   E 1 454 ? 273.918 255.206 204.249 1.00 46.07  ? 466 LEU   B CD1    1 
ATOM   4389 C CD2    . LEU   E 1 454 ? 272.766 256.399 202.389 1.00 46.30  ? 466 LEU   B CD2    1 
ATOM   4390 N N      . SER   E 1 455 ? 273.540 260.283 205.881 1.00 44.12  ? 467 SER   B N      1 
ATOM   4391 C CA     . SER   E 1 455 ? 273.813 261.046 207.090 1.00 47.06  ? 467 SER   B CA     1 
ATOM   4392 C C      . SER   E 1 455 ? 272.559 261.328 207.905 1.00 49.07  ? 467 SER   B C      1 
ATOM   4393 O O      . SER   E 1 455 ? 272.672 261.689 209.080 1.00 51.87  ? 467 SER   B O      1 
ATOM   4394 C CB     . SER   E 1 455 ? 274.498 262.365 206.731 1.00 51.37  ? 467 SER   B CB     1 
ATOM   4395 O OG     . SER   E 1 455 ? 275.622 262.139 205.901 1.00 55.35  ? 467 SER   B OG     1 
ATOM   4396 N N      . ASP   E 1 456 ? 271.379 261.172 207.312 1.00 49.90  ? 468 ASP   B N      1 
ATOM   4397 C CA     . ASP   E 1 456 ? 270.103 261.397 207.987 1.00 48.64  ? 468 ASP   B CA     1 
ATOM   4398 C C      . ASP   E 1 456 ? 269.632 260.051 208.525 1.00 51.53  ? 468 ASP   B C      1 
ATOM   4399 O O      . ASP   E 1 456 ? 268.899 259.317 207.862 1.00 56.90  ? 468 ASP   B O      1 
ATOM   4400 C CB     . ASP   E 1 456 ? 269.091 262.015 207.027 1.00 48.34  ? 468 ASP   B CB     1 
ATOM   4401 C CG     . ASP   E 1 456 ? 267.759 262.314 207.684 1.00 52.90  ? 468 ASP   B CG     1 
ATOM   4402 O OD1    . ASP   E 1 456 ? 267.387 261.619 208.652 1.00 58.92  ? 468 ASP   B OD1    1 
ATOM   4403 O OD2    . ASP   E 1 456 ? 267.073 263.248 207.224 1.00 52.61  ? 468 ASP   B OD2    1 
ATOM   4404 N N      . GLU   E 1 457 ? 270.056 259.726 209.744 1.00 49.17  ? 469 GLU   B N      1 
ATOM   4405 C CA     . GLU   E 1 457 ? 269.707 258.443 210.337 1.00 52.34  ? 469 GLU   B CA     1 
ATOM   4406 C C      . GLU   E 1 457 ? 268.312 258.421 210.943 1.00 55.35  ? 469 GLU   B C      1 
ATOM   4407 O O      . GLU   E 1 457 ? 267.808 257.335 211.247 1.00 58.58  ? 469 GLU   B O      1 
ATOM   4408 C CB     . GLU   E 1 457 ? 270.731 258.064 211.407 1.00 51.98  ? 469 GLU   B CB     1 
ATOM   4409 C CG     . GLU   E 1 457 ? 272.170 258.308 211.004 1.00 53.79  ? 469 GLU   B CG     1 
ATOM   4410 C CD     . GLU   E 1 457 ? 272.986 257.033 210.978 1.00 62.65  ? 469 GLU   B CD     1 
ATOM   4411 O OE1    . GLU   E 1 457 ? 274.226 257.117 211.091 1.00 69.24  ? 469 GLU   B OE1    1 
ATOM   4412 O OE2    . GLU   E 1 457 ? 272.387 255.946 210.848 1.00 62.94  ? 469 GLU   B OE2    1 
ATOM   4413 N N      . LYS   E 1 458 ? 267.675 259.575 211.123 1.00 53.98  ? 470 LYS   B N      1 
ATOM   4414 C CA     . LYS   E 1 458 ? 266.377 259.640 211.776 1.00 57.21  ? 470 LYS   B CA     1 
ATOM   4415 C C      . LYS   E 1 458 ? 265.220 259.836 210.807 1.00 55.68  ? 470 LYS   B C      1 
ATOM   4416 O O      . LYS   E 1 458 ? 264.083 260.012 211.255 1.00 61.31  ? 470 LYS   B O      1 
ATOM   4417 C CB     . LYS   E 1 458 ? 266.367 260.759 212.822 1.00 59.81  ? 470 LYS   B CB     1 
ATOM   4418 C CG     . LYS   E 1 458 ? 267.052 260.386 214.126 1.00 65.61  ? 470 LYS   B CG     1 
ATOM   4419 C CD     . LYS   E 1 458 ? 266.131 259.581 215.030 1.00 73.53  ? 470 LYS   B CD     1 
ATOM   4420 C CE     . LYS   E 1 458 ? 264.727 260.162 215.080 1.00 79.35  ? 470 LYS   B CE     1 
ATOM   4421 N NZ     . LYS   E 1 458 ? 264.723 261.652 215.058 1.00 82.80  ? 470 LYS   B NZ     1 
ATOM   4422 N N      . ALA   E 1 459 ? 265.470 259.804 209.500 1.00 49.01  ? 471 ALA   B N      1 
ATOM   4423 C CA     . ALA   E 1 459 ? 264.402 259.927 208.509 1.00 50.63  ? 471 ALA   B CA     1 
ATOM   4424 C C      . ALA   E 1 459 ? 263.626 261.227 208.697 1.00 52.12  ? 471 ALA   B C      1 
ATOM   4425 O O      . ALA   E 1 459 ? 262.396 261.232 208.779 1.00 55.77  ? 471 ALA   B O      1 
ATOM   4426 C CB     . ALA   E 1 459 ? 263.462 258.723 208.561 1.00 49.58  ? 471 ALA   B CB     1 
ATOM   4427 N N      . THR   E 1 460 ? 264.349 262.341 208.768 1.00 52.01  ? 472 THR   B N      1 
ATOM   4428 C CA     . THR   E 1 460 ? 263.730 263.634 209.025 1.00 50.64  ? 472 THR   B CA     1 
ATOM   4429 C C      . THR   E 1 460 ? 263.289 264.334 207.743 1.00 49.67  ? 472 THR   B C      1 
ATOM   4430 O O      . THR   E 1 460 ? 262.136 264.761 207.634 1.00 51.72  ? 472 THR   B O      1 
ATOM   4431 C CB     . THR   E 1 460 ? 264.694 264.529 209.808 1.00 50.98  ? 472 THR   B CB     1 
ATOM   4432 O OG1    . THR   E 1 460 ? 265.557 265.218 208.897 1.00 52.66  ? 472 THR   B OG1    1 
ATOM   4433 C CG2    . THR   E 1 460 ? 265.535 263.698 210.760 1.00 53.22  ? 472 THR   B CG2    1 
ATOM   4434 N N      . SER   E 1 461 ? 264.183 264.457 206.764 1.00 51.11  ? 473 SER   B N      1 
ATOM   4435 C CA     . SER   E 1 461 ? 263.892 265.222 205.555 1.00 51.64  ? 473 SER   B CA     1 
ATOM   4436 C C      . SER   E 1 461 ? 263.826 264.304 204.343 1.00 50.15  ? 473 SER   B C      1 
ATOM   4437 O O      . SER   E 1 461 ? 264.872 263.916 203.801 1.00 48.80  ? 473 SER   B O      1 
ATOM   4438 C CB     . SER   E 1 461 ? 264.950 266.308 205.342 1.00 52.51  ? 473 SER   B CB     1 
ATOM   4439 O OG     . SER   E 1 461 ? 266.223 265.736 205.103 1.00 53.11  ? 473 SER   B OG     1 
ATOM   4440 N N      . PRO   E 1 462 ? 262.637 263.930 203.878 1.00 52.44  ? 474 PRO   B N      1 
ATOM   4441 C CA     . PRO   E 1 462 ? 262.547 263.132 202.652 1.00 51.65  ? 474 PRO   B CA     1 
ATOM   4442 C C      . PRO   E 1 462 ? 262.934 263.946 201.429 1.00 49.22  ? 474 PRO   B C      1 
ATOM   4443 O O      . PRO   E 1 462 ? 262.804 265.172 201.399 1.00 55.05  ? 474 PRO   B O      1 
ATOM   4444 C CB     . PRO   E 1 462 ? 261.071 262.715 202.600 1.00 49.43  ? 474 PRO   B CB     1 
ATOM   4445 C CG     . PRO   E 1 462 ? 260.508 263.038 203.953 1.00 44.40  ? 474 PRO   B CG     1 
ATOM   4446 C CD     . PRO   E 1 462 ? 261.318 264.172 204.478 1.00 51.14  ? 474 PRO   B CD     1 
ATOM   4447 N N      . ILE   E 1 463 ? 263.418 263.243 200.410 1.00 46.31  ? 475 ILE   B N      1 
ATOM   4448 C CA     . ILE   E 1 463 ? 263.825 263.847 199.146 1.00 46.63  ? 475 ILE   B CA     1 
ATOM   4449 C C      . ILE   E 1 463 ? 262.969 263.207 198.061 1.00 47.74  ? 475 ILE   B C      1 
ATOM   4450 O O      . ILE   E 1 463 ? 263.288 262.121 197.564 1.00 49.22  ? 475 ILE   B O      1 
ATOM   4451 C CB     . ILE   E 1 463 ? 265.318 263.655 198.863 1.00 47.67  ? 475 ILE   B CB     1 
ATOM   4452 C CG1    . ILE   E 1 463 ? 266.158 264.465 199.848 1.00 46.27  ? 475 ILE   B CG1    1 
ATOM   4453 C CG2    . ILE   E 1 463 ? 265.645 264.061 197.438 1.00 44.94  ? 475 ILE   B CG2    1 
ATOM   4454 C CD1    . ILE   E 1 463 ? 267.516 264.840 199.312 1.00 49.48  ? 475 ILE   B CD1    1 
ATOM   4455 N N      . VAL   E 1 464 ? 261.880 263.872 197.690 1.00 48.32  ? 476 VAL   B N      1 
ATOM   4456 C CA     . VAL   E 1 464 ? 260.946 263.337 196.703 1.00 46.24  ? 476 VAL   B CA     1 
ATOM   4457 C C      . VAL   E 1 464 ? 261.576 263.416 195.317 1.00 48.15  ? 476 VAL   B C      1 
ATOM   4458 O O      . VAL   E 1 464 ? 262.033 264.490 194.903 1.00 47.86  ? 476 VAL   B O      1 
ATOM   4459 C CB     . VAL   E 1 464 ? 259.603 264.080 196.746 1.00 46.31  ? 476 VAL   B CB     1 
ATOM   4460 C CG1    . VAL   E 1 464 ? 258.657 263.515 195.705 1.00 51.48  ? 476 VAL   B CG1    1 
ATOM   4461 C CG2    . VAL   E 1 464 ? 258.992 263.983 198.132 1.00 51.31  ? 476 VAL   B CG2    1 
ATOM   4462 N N      . PRO   E 1 465 ? 261.628 262.316 194.575 1.00 50.21  ? 477 PRO   B N      1 
ATOM   4463 C CA     . PRO   E 1 465 ? 262.260 262.338 193.255 1.00 47.38  ? 477 PRO   B CA     1 
ATOM   4464 C C      . PRO   E 1 465 ? 261.311 262.824 192.170 1.00 45.86  ? 477 PRO   B C      1 
ATOM   4465 O O      . PRO   E 1 465 ? 260.087 262.744 192.284 1.00 44.20  ? 477 PRO   B O      1 
ATOM   4466 C CB     . PRO   E 1 465 ? 262.635 260.871 193.032 1.00 47.92  ? 477 PRO   B CB     1 
ATOM   4467 C CG     . PRO   E 1 465 ? 261.555 260.127 193.742 1.00 47.47  ? 477 PRO   B CG     1 
ATOM   4468 C CD     . PRO   E 1 465 ? 261.177 260.964 194.945 1.00 52.24  ? 477 PRO   B CD     1 
ATOM   4469 N N      . SER   E 1 466 ? 261.909 263.333 191.098 1.00 45.61  ? 478 SER   B N      1 
ATOM   4470 C CA     . SER   E 1 466 ? 261.186 263.700 189.890 1.00 45.53  ? 478 SER   B CA     1 
ATOM   4471 C C      . SER   E 1 466 ? 261.702 262.846 188.744 1.00 48.37  ? 478 SER   B C      1 
ATOM   4472 O O      . SER   E 1 466 ? 262.907 262.829 188.473 1.00 49.99  ? 478 SER   B O      1 
ATOM   4473 C CB     . SER   E 1 466 ? 261.354 265.185 189.567 1.00 46.64  ? 478 SER   B CB     1 
ATOM   4474 O OG     . SER   E 1 466 ? 262.721 265.520 189.418 1.00 49.89  ? 478 SER   B OG     1 
ATOM   4475 N N      . PHE   E 1 467 ? 260.796 262.143 188.076 1.00 46.07  ? 479 PHE   B N      1 
ATOM   4476 C CA     . PHE   E 1 467 ? 261.181 261.238 187.003 1.00 47.95  ? 479 PHE   B CA     1 
ATOM   4477 C C      . PHE   E 1 467 ? 260.714 261.764 185.651 1.00 44.92  ? 479 PHE   B C      1 
ATOM   4478 O O      . PHE   E 1 467 ? 260.330 260.994 184.774 1.00 46.67  ? 479 PHE   B O      1 
ATOM   4479 C CB     . PHE   E 1 467 ? 260.614 259.842 187.258 1.00 47.71  ? 479 PHE   B CB     1 
ATOM   4480 C CG     . PHE   E 1 467 ? 261.080 259.225 188.546 1.00 45.94  ? 479 PHE   B CG     1 
ATOM   4481 C CD1    . PHE   E 1 467 ? 262.399 259.336 188.944 1.00 43.71  ? 479 PHE   B CD1    1 
ATOM   4482 C CD2    . PHE   E 1 467 ? 260.197 258.541 189.361 1.00 45.07  ? 479 PHE   B CD2    1 
ATOM   4483 C CE1    . PHE   E 1 467 ? 262.829 258.773 190.127 1.00 44.94  ? 479 PHE   B CE1    1 
ATOM   4484 C CE2    . PHE   E 1 467 ? 260.623 257.977 190.546 1.00 39.95  ? 479 PHE   B CE2    1 
ATOM   4485 C CZ     . PHE   E 1 467 ? 261.939 258.092 190.928 1.00 42.23  ? 479 PHE   B CZ     1 
ATOM   4486 N N      . GLU   E 1 472 ? 265.072 254.947 180.250 1.00 66.53  ? 484 GLU   B N      1 
ATOM   4487 C CA     . GLU   E 1 472 ? 263.679 255.412 180.484 1.00 61.04  ? 484 GLU   B CA     1 
ATOM   4488 C C      . GLU   E 1 472 ? 262.813 254.222 180.921 1.00 60.05  ? 484 GLU   B C      1 
ATOM   4489 O O      . GLU   E 1 472 ? 261.716 254.460 181.470 1.00 57.50  ? 484 GLU   B O      1 
ATOM   4490 C CB     . GLU   E 1 472 ? 263.110 256.059 179.221 1.00 60.52  ? 484 GLU   B CB     1 
ATOM   4491 C CG     . GLU   E 1 472 ? 263.805 257.366 178.847 1.00 69.95  ? 484 GLU   B CG     1 
ATOM   4492 C CD     . GLU   E 1 472 ? 263.300 257.984 177.557 1.00 72.35  ? 484 GLU   B CD     1 
ATOM   4493 O OE1    . GLU   E 1 472 ? 262.535 257.307 176.838 1.00 68.89  ? 484 GLU   B OE1    1 
ATOM   4494 O OE2    . GLU   E 1 472 ? 263.666 259.144 177.275 1.00 63.99  ? 484 GLU   B OE2    1 
ATOM   4495 N N      . GLY   E 1 473 ? 263.287 252.994 180.685 1.00 60.55  ? 485 GLY   B N      1 
ATOM   4496 C CA     . GLY   E 1 473 ? 262.530 251.821 181.062 1.00 53.15  ? 485 GLY   B CA     1 
ATOM   4497 C C      . GLY   E 1 473 ? 262.349 251.700 182.562 1.00 52.32  ? 485 GLY   B C      1 
ATOM   4498 O O      . GLY   E 1 473 ? 263.101 252.254 183.363 1.00 56.51  ? 485 GLY   B O      1 
ATOM   4499 N N      . SER   E 1 474 ? 261.317 250.951 182.944 1.00 46.94  ? 486 SER   B N      1 
ATOM   4500 C CA     . SER   E 1 474 ? 261.008 250.749 184.352 1.00 44.78  ? 486 SER   B CA     1 
ATOM   4501 C C      . SER   E 1 474 ? 260.772 249.292 184.721 1.00 44.42  ? 486 SER   B C      1 
ATOM   4502 O O      . SER   E 1 474 ? 260.356 249.026 185.852 1.00 44.29  ? 486 SER   B O      1 
ATOM   4503 C CB     . SER   E 1 474 ? 259.777 251.574 184.751 1.00 44.23  ? 486 SER   B CB     1 
ATOM   4504 O OG     . SER   E 1 474 ? 258.616 251.102 184.092 1.00 55.42  ? 486 SER   B OG     1 
ATOM   4505 N N      . TYR   E 1 475 ? 261.016 248.348 183.818 1.00 44.37  ? 487 TYR   B N      1 
ATOM   4506 C CA     . TYR   E 1 475 ? 260.802 246.931 184.078 1.00 42.45  ? 487 TYR   B CA     1 
ATOM   4507 C C      . TYR   E 1 475 ? 262.143 246.217 184.022 1.00 41.79  ? 487 TYR   B C      1 
ATOM   4508 O O      . TYR   E 1 475 ? 262.820 246.242 182.989 1.00 39.50  ? 487 TYR   B O      1 
ATOM   4509 C CB     . TYR   E 1 475 ? 259.830 246.329 183.062 1.00 43.19  ? 487 TYR   B CB     1 
ATOM   4510 C CG     . TYR   E 1 475 ? 258.458 246.954 183.094 1.00 48.85  ? 487 TYR   B CG     1 
ATOM   4511 C CD1    . TYR   E 1 475 ? 257.723 247.112 181.931 1.00 52.43  ? 487 TYR   B CD1    1 
ATOM   4512 C CD2    . TYR   E 1 475 ? 257.899 247.390 184.286 1.00 49.07  ? 487 TYR   B CD2    1 
ATOM   4513 C CE1    . TYR   E 1 475 ? 256.471 247.685 181.953 1.00 53.60  ? 487 TYR   B CE1    1 
ATOM   4514 C CE2    . TYR   E 1 475 ? 256.646 247.965 184.317 1.00 43.58  ? 487 TYR   B CE2    1 
ATOM   4515 C CZ     . TYR   E 1 475 ? 255.938 248.109 183.147 1.00 50.49  ? 487 TYR   B CZ     1 
ATOM   4516 O OH     . TYR   E 1 475 ? 254.689 248.680 183.168 1.00 65.16  ? 487 TYR   B OH     1 
ATOM   4517 N N      . PHE   E 1 476 ? 262.526 245.583 185.130 1.00 41.01  ? 488 PHE   B N      1 
ATOM   4518 C CA     . PHE   E 1 476 ? 263.783 244.845 185.157 1.00 40.76  ? 488 PHE   B CA     1 
ATOM   4519 C C      . PHE   E 1 476 ? 263.732 243.653 184.208 1.00 39.44  ? 488 PHE   B C      1 
ATOM   4520 O O      . PHE   E 1 476 ? 264.629 243.466 183.379 1.00 35.30  ? 488 PHE   B O      1 
ATOM   4521 C CB     . PHE   E 1 476 ? 264.094 244.397 186.586 1.00 36.07  ? 488 PHE   B CB     1 
ATOM   4522 C CG     . PHE   E 1 476 ? 265.456 243.788 186.752 1.00 37.70  ? 488 PHE   B CG     1 
ATOM   4523 C CD1    . PHE   E 1 476 ? 266.593 244.485 186.387 1.00 42.24  ? 488 PHE   B CD1    1 
ATOM   4524 C CD2    . PHE   E 1 476 ? 265.602 242.522 187.288 1.00 38.57  ? 488 PHE   B CD2    1 
ATOM   4525 C CE1    . PHE   E 1 476 ? 267.846 243.927 186.545 1.00 41.26  ? 488 PHE   B CE1    1 
ATOM   4526 C CE2    . PHE   E 1 476 ? 266.854 241.960 187.447 1.00 38.17  ? 488 PHE   B CE2    1 
ATOM   4527 C CZ     . PHE   E 1 476 ? 267.976 242.664 187.075 1.00 37.06  ? 488 PHE   B CZ     1 
ATOM   4528 N N      . PHE   E 1 477 ? 262.686 242.842 184.312 1.00 39.77  ? 489 PHE   B N      1 
ATOM   4529 C CA     . PHE   E 1 477 ? 262.488 241.684 183.439 1.00 39.72  ? 489 PHE   B CA     1 
ATOM   4530 C C      . PHE   E 1 477 ? 261.578 242.024 182.265 1.00 43.27  ? 489 PHE   B C      1 
ATOM   4531 O O      . PHE   E 1 477 ? 260.535 241.406 182.066 1.00 46.20  ? 489 PHE   B O      1 
ATOM   4532 C CB     . PHE   E 1 477 ? 261.930 240.516 184.242 1.00 37.89  ? 489 PHE   B CB     1 
ATOM   4533 C CG     . PHE   E 1 477 ? 262.890 239.960 185.255 1.00 41.22  ? 489 PHE   B CG     1 
ATOM   4534 C CD1    . PHE   E 1 477 ? 264.097 239.414 184.859 1.00 41.35  ? 489 PHE   B CD1    1 
ATOM   4535 C CD2    . PHE   E 1 477 ? 262.584 239.982 186.603 1.00 43.92  ? 489 PHE   B CD2    1 
ATOM   4536 C CE1    . PHE   E 1 477 ? 264.980 238.903 185.788 1.00 38.26  ? 489 PHE   B CE1    1 
ATOM   4537 C CE2    . PHE   E 1 477 ? 263.462 239.470 187.535 1.00 42.18  ? 489 PHE   B CE2    1 
ATOM   4538 C CZ     . PHE   E 1 477 ? 264.661 238.931 187.126 1.00 36.82  ? 489 PHE   B CZ     1 
ATOM   4539 N N      . GLY   E 1 478 ? 261.965 243.014 181.468 1.00 40.84  ? 490 GLY   B N      1 
ATOM   4540 C CA     . GLY   E 1 478 ? 261.149 243.452 180.351 1.00 35.80  ? 490 GLY   B CA     1 
ATOM   4541 C C      . GLY   E 1 478 ? 261.742 243.121 178.996 1.00 41.25  ? 490 GLY   B C      1 
ATOM   4542 O O      . GLY   E 1 478 ? 261.023 243.018 178.002 1.00 36.06  ? 490 GLY   B O      1 
ATOM   4543 N N      . THR   F 1 3   ? 219.950 262.088 246.370 1.00 78.40  ? 15  THR   A N      1 
ATOM   4544 C CA     . THR   F 1 3   ? 220.383 263.456 246.625 1.00 81.29  ? 15  THR   A CA     1 
ATOM   4545 C C      . THR   F 1 3   ? 220.154 263.827 248.086 1.00 82.32  ? 15  THR   A C      1 
ATOM   4546 O O      . THR   F 1 3   ? 219.507 263.090 248.826 1.00 87.38  ? 15  THR   A O      1 
ATOM   4547 C CB     . THR   F 1 3   ? 219.646 264.461 245.722 1.00 85.97  ? 15  THR   A CB     1 
ATOM   4548 O OG1    . THR   F 1 3   ? 219.510 263.912 244.405 1.00 97.91  ? 15  THR   A OG1    1 
ATOM   4549 C CG2    . THR   F 1 3   ? 220.417 265.766 245.635 1.00 72.03  ? 15  THR   A CG2    1 
ATOM   4550 N N      . ASP   F 1 4   ? 220.705 264.970 248.493 1.00 85.36  ? 16  ASP   A N      1 
ATOM   4551 C CA     . ASP   F 1 4   ? 220.598 265.457 249.864 1.00 96.14  ? 16  ASP   A CA     1 
ATOM   4552 C C      . ASP   F 1 4   ? 221.522 264.637 250.756 1.00 90.99  ? 16  ASP   A C      1 
ATOM   4553 O O      . ASP   F 1 4   ? 221.723 264.954 251.932 1.00 93.44  ? 16  ASP   A O      1 
ATOM   4554 C CB     . ASP   F 1 4   ? 219.145 265.383 250.346 1.00 106.36 ? 16  ASP   A CB     1 
ATOM   4555 C CG     . ASP   F 1 4   ? 218.968 265.871 251.772 1.00 119.00 ? 16  ASP   A CG     1 
ATOM   4556 O OD1    . ASP   F 1 4   ? 219.918 266.448 252.340 1.00 124.01 ? 16  ASP   A OD1    1 
ATOM   4557 O OD2    . ASP   F 1 4   ? 217.869 265.674 252.329 1.00 121.62 ? 16  ASP   A OD2    1 
ATOM   4558 N N      . GLY   F 1 5   ? 222.105 263.590 250.186 1.00 81.13  ? 17  GLY   A N      1 
ATOM   4559 C CA     . GLY   F 1 5   ? 223.143 262.823 250.837 1.00 77.26  ? 17  GLY   A CA     1 
ATOM   4560 C C      . GLY   F 1 5   ? 224.361 262.759 249.944 1.00 75.26  ? 17  GLY   A C      1 
ATOM   4561 O O      . GLY   F 1 5   ? 225.484 262.554 250.411 1.00 72.89  ? 17  GLY   A O      1 
ATOM   4562 N N      . GLU   F 1 6   ? 224.143 262.935 248.645 1.00 77.00  ? 18  GLU   A N      1 
ATOM   4563 C CA     . GLU   F 1 6   ? 225.233 263.010 247.686 1.00 71.73  ? 18  GLU   A CA     1 
ATOM   4564 C C      . GLU   F 1 6   ? 225.794 264.419 247.551 1.00 71.67  ? 18  GLU   A C      1 
ATOM   4565 O O      . GLU   F 1 6   ? 226.838 264.594 246.916 1.00 69.91  ? 18  GLU   A O      1 
ATOM   4566 C CB     . GLU   F 1 6   ? 224.771 262.423 246.335 1.00 68.63  ? 18  GLU   A CB     1 
ATOM   4567 C CG     . GLU   F 1 6   ? 223.713 263.185 245.510 1.00 79.22  ? 18  GLU   A CG     1 
ATOM   4568 C CD     . GLU   F 1 6   ? 224.118 264.546 244.963 1.00 93.13  ? 18  GLU   A CD     1 
ATOM   4569 O OE1    . GLU   F 1 6   ? 223.272 265.156 244.279 1.00 97.69  ? 18  GLU   A OE1    1 
ATOM   4570 O OE2    . GLU   F 1 6   ? 225.276 264.978 245.122 1.00 90.14  ? 18  GLU   A OE2    1 
ATOM   4571 N N      . ARG   F 1 7   ? 225.151 265.418 248.163 1.00 72.77  ? 19  ARG   A N      1 
ATOM   4572 C CA     . ARG   F 1 7   ? 225.765 266.739 248.253 1.00 67.45  ? 19  ARG   A CA     1 
ATOM   4573 C C      . ARG   F 1 7   ? 227.107 266.667 248.970 1.00 63.04  ? 19  ARG   A C      1 
ATOM   4574 O O      . ARG   F 1 7   ? 228.094 267.261 248.521 1.00 60.85  ? 19  ARG   A O      1 
ATOM   4575 C CB     . ARG   F 1 7   ? 224.824 267.714 248.967 1.00 70.39  ? 19  ARG   A CB     1 
ATOM   4576 C CG     . ARG   F 1 7   ? 224.940 267.697 250.493 1.00 80.87  ? 19  ARG   A CG     1 
ATOM   4577 C CD     . ARG   F 1 7   ? 224.663 269.056 251.129 1.00 83.77  ? 19  ARG   A CD     1 
ATOM   4578 N NE     . ARG   F 1 7   ? 224.996 269.060 252.550 1.00 82.91  ? 19  ARG   A NE     1 
ATOM   4579 C CZ     . ARG   F 1 7   ? 224.663 270.023 253.400 1.00 69.55  ? 19  ARG   A CZ     1 
ATOM   4580 N NH1    . ARG   F 1 7   ? 223.998 271.096 253.004 1.00 63.08  ? 19  ARG   A NH1    1 
ATOM   4581 N NH2    . ARG   F 1 7   ? 225.012 269.910 254.678 1.00 53.96  ? 19  ARG   A NH2    1 
ATOM   4582 N N      . GLN   F 1 8   ? 227.162 265.945 250.091 1.00 63.04  ? 20  GLN   A N      1 
ATOM   4583 C CA     . GLN   F 1 8   ? 228.428 265.763 250.791 1.00 65.37  ? 20  GLN   A CA     1 
ATOM   4584 C C      . GLN   F 1 8   ? 229.420 264.994 249.934 1.00 63.73  ? 20  GLN   A C      1 
ATOM   4585 O O      . GLN   F 1 8   ? 230.605 265.344 249.874 1.00 64.29  ? 20  GLN   A O      1 
ATOM   4586 C CB     . GLN   F 1 8   ? 228.190 265.043 252.118 1.00 67.66  ? 20  GLN   A CB     1 
ATOM   4587 C CG     . GLN   F 1 8   ? 229.253 265.291 253.173 1.00 66.56  ? 20  GLN   A CG     1 
ATOM   4588 C CD     . GLN   F 1 8   ? 229.637 266.750 253.304 1.00 73.30  ? 20  GLN   A CD     1 
ATOM   4589 O OE1    . GLN   F 1 8   ? 229.016 267.628 252.709 1.00 74.35  ? 20  GLN   A OE1    1 
ATOM   4590 N NE2    . GLN   F 1 8   ? 230.673 267.015 254.090 1.00 79.60  ? 20  GLN   A NE2    1 
ATOM   4591 N N      . ASN   F 1 9   ? 228.955 263.943 249.259 1.00 62.24  ? 21  ASN   A N      1 
ATOM   4592 C CA     . ASN   F 1 9   ? 229.841 263.175 248.394 1.00 59.88  ? 21  ASN   A CA     1 
ATOM   4593 C C      . ASN   F 1 9   ? 230.378 264.034 247.258 1.00 59.28  ? 21  ASN   A C      1 
ATOM   4594 O O      . ASN   F 1 9   ? 231.571 263.983 246.940 1.00 60.24  ? 21  ASN   A O      1 
ATOM   4595 C CB     . ASN   F 1 9   ? 229.104 261.954 247.846 1.00 60.68  ? 21  ASN   A CB     1 
ATOM   4596 C CG     . ASN   F 1 9   ? 230.040 260.822 247.493 1.00 66.14  ? 21  ASN   A CG     1 
ATOM   4597 O OD1    . ASN   F 1 9   ? 231.260 260.972 247.546 1.00 71.91  ? 21  ASN   A OD1    1 
ATOM   4598 N ND2    . ASN   F 1 9   ? 229.474 259.680 247.126 1.00 64.61  ? 21  ASN   A ND2    1 
ATOM   4599 N N      . ALA   F 1 10  ? 229.513 264.841 246.639 1.00 61.01  ? 22  ALA   A N      1 
ATOM   4600 C CA     . ALA   F 1 10  ? 229.958 265.706 245.553 1.00 58.33  ? 22  ALA   A CA     1 
ATOM   4601 C C      . ALA   F 1 10  ? 230.967 266.737 246.042 1.00 55.66  ? 22  ALA   A C      1 
ATOM   4602 O O      . ALA   F 1 10  ? 231.972 266.999 245.372 1.00 53.82  ? 22  ALA   A O      1 
ATOM   4603 C CB     . ALA   F 1 10  ? 228.758 266.393 244.905 1.00 61.33  ? 22  ALA   A CB     1 
ATOM   4604 N N      . THR   F 1 11  ? 230.715 267.335 247.207 1.00 56.49  ? 23  THR   A N      1 
ATOM   4605 C CA     . THR   F 1 11  ? 231.657 268.307 247.750 1.00 54.80  ? 23  THR   A CA     1 
ATOM   4606 C C      . THR   F 1 11  ? 232.996 267.655 248.067 1.00 56.38  ? 23  THR   A C      1 
ATOM   4607 O O      . THR   F 1 11  ? 234.054 268.258 247.859 1.00 53.61  ? 23  THR   A O      1 
ATOM   4608 C CB     . THR   F 1 11  ? 231.074 268.970 248.998 1.00 55.83  ? 23  THR   A CB     1 
ATOM   4609 O OG1    . THR   F 1 11  ? 229.743 269.420 248.724 1.00 60.34  ? 23  THR   A OG1    1 
ATOM   4610 C CG2    . THR   F 1 11  ? 231.924 270.155 249.415 1.00 47.72  ? 23  THR   A CG2    1 
ATOM   4611 N N      . GLU   F 1 12  ? 232.969 266.423 248.579 1.00 57.72  ? 24  GLU   A N      1 
ATOM   4612 C CA     . GLU   F 1 12  ? 234.210 265.708 248.853 1.00 57.32  ? 24  GLU   A CA     1 
ATOM   4613 C C      . GLU   F 1 12  ? 235.005 265.468 247.576 1.00 56.30  ? 24  GLU   A C      1 
ATOM   4614 O O      . GLU   F 1 12  ? 236.222 265.684 247.545 1.00 55.87  ? 24  GLU   A O      1 
ATOM   4615 C CB     . GLU   F 1 12  ? 233.905 264.383 249.551 1.00 60.99  ? 24  GLU   A CB     1 
ATOM   4616 C CG     . GLU   F 1 12  ? 233.839 264.477 251.063 1.00 68.44  ? 24  GLU   A CG     1 
ATOM   4617 C CD     . GLU   F 1 12  ? 234.594 265.672 251.605 1.00 85.33  ? 24  GLU   A CD     1 
ATOM   4618 O OE1    . GLU   F 1 12  ? 235.799 265.801 251.299 1.00 87.34  ? 24  GLU   A OE1    1 
ATOM   4619 O OE2    . GLU   F 1 12  ? 233.986 266.483 252.335 1.00 85.37  ? 24  GLU   A OE2    1 
ATOM   4620 N N      . ILE   F 1 13  ? 234.334 265.025 246.510 1.00 54.58  ? 25  ILE   A N      1 
ATOM   4621 C CA     . ILE   F 1 13  ? 235.028 264.756 245.253 1.00 51.43  ? 25  ILE   A CA     1 
ATOM   4622 C C      . ILE   F 1 13  ? 235.623 266.037 244.683 1.00 50.33  ? 25  ILE   A C      1 
ATOM   4623 O O      . ILE   F 1 13  ? 236.718 266.027 244.108 1.00 48.58  ? 25  ILE   A O      1 
ATOM   4624 C CB     . ILE   F 1 13  ? 234.077 264.079 244.249 1.00 51.58  ? 25  ILE   A CB     1 
ATOM   4625 C CG1    . ILE   F 1 13  ? 233.396 262.872 244.888 1.00 56.69  ? 25  ILE   A CG1    1 
ATOM   4626 C CG2    . ILE   F 1 13  ? 234.835 263.650 243.007 1.00 50.07  ? 25  ILE   A CG2    1 
ATOM   4627 C CD1    . ILE   F 1 13  ? 234.347 261.956 245.620 1.00 61.03  ? 25  ILE   A CD1    1 
ATOM   4628 N N      . ARG   F 1 14  ? 234.909 267.155 244.821 1.00 51.56  ? 26  ARG   A N      1 
ATOM   4629 C CA     . ARG   F 1 14  ? 235.406 268.420 244.289 1.00 50.13  ? 26  ARG   A CA     1 
ATOM   4630 C C      . ARG   F 1 14  ? 236.719 268.820 244.949 1.00 52.22  ? 26  ARG   A C      1 
ATOM   4631 O O      . ARG   F 1 14  ? 237.650 269.272 244.274 1.00 51.76  ? 26  ARG   A O      1 
ATOM   4632 C CB     . ARG   F 1 14  ? 234.354 269.515 244.473 1.00 47.39  ? 26  ARG   A CB     1 
ATOM   4633 C CG     . ARG   F 1 14  ? 233.284 269.533 243.398 1.00 44.10  ? 26  ARG   A CG     1 
ATOM   4634 C CD     . ARG   F 1 14  ? 232.403 270.765 243.511 1.00 42.17  ? 26  ARG   A CD     1 
ATOM   4635 N NE     . ARG   F 1 14  ? 232.412 271.560 242.289 1.00 47.39  ? 26  ARG   A NE     1 
ATOM   4636 C CZ     . ARG   F 1 14  ? 233.000 272.741 242.170 1.00 49.04  ? 26  ARG   A CZ     1 
ATOM   4637 N NH1    . ARG   F 1 14  ? 233.631 273.305 243.186 1.00 52.32  ? 26  ARG   A NH1    1 
ATOM   4638 N NH2    . ARG   F 1 14  ? 232.952 273.375 241.002 1.00 49.96  ? 26  ARG   A NH2    1 
ATOM   4639 N N      . ALA   F 1 15  ? 236.813 268.657 246.270 1.00 51.69  ? 27  ALA   A N      1 
ATOM   4640 C CA     . ALA   F 1 15  ? 238.042 269.009 246.973 1.00 48.51  ? 27  ALA   A CA     1 
ATOM   4641 C C      . ALA   F 1 15  ? 239.206 268.129 246.533 1.00 46.50  ? 27  ALA   A C      1 
ATOM   4642 O O      . ALA   F 1 15  ? 240.335 268.609 246.386 1.00 45.04  ? 27  ALA   A O      1 
ATOM   4643 C CB     . ALA   F 1 15  ? 237.829 268.907 248.482 1.00 49.18  ? 27  ALA   A CB     1 
ATOM   4644 N N      . SER   F 1 16  ? 238.953 266.836 246.324 1.00 46.37  ? 28  SER   A N      1 
ATOM   4645 C CA     . SER   F 1 16  ? 240.023 265.929 245.923 1.00 46.49  ? 28  SER   A CA     1 
ATOM   4646 C C      . SER   F 1 16  ? 240.555 266.284 244.539 1.00 45.09  ? 28  SER   A C      1 
ATOM   4647 O O      . SER   F 1 16  ? 241.765 266.217 244.292 1.00 42.35  ? 28  SER   A O      1 
ATOM   4648 C CB     . SER   F 1 16  ? 239.528 264.483 245.962 1.00 44.90  ? 28  SER   A CB     1 
ATOM   4649 O OG     . SER   F 1 16  ? 238.758 264.173 244.816 1.00 56.21  ? 28  SER   A OG     1 
ATOM   4650 N N      . VAL   F 1 17  ? 239.664 266.653 243.617 1.00 46.34  ? 29  VAL   A N      1 
ATOM   4651 C CA     . VAL   F 1 17  ? 240.113 267.076 242.295 1.00 46.79  ? 29  VAL   A CA     1 
ATOM   4652 C C      . VAL   F 1 17  ? 240.834 268.413 242.376 1.00 45.46  ? 29  VAL   A C      1 
ATOM   4653 O O      . VAL   F 1 17  ? 241.837 268.629 241.686 1.00 46.95  ? 29  VAL   A O      1 
ATOM   4654 C CB     . VAL   F 1 17  ? 238.927 267.134 241.316 1.00 44.62  ? 29  VAL   A CB     1 
ATOM   4655 C CG1    . VAL   F 1 17  ? 239.357 267.762 240.004 1.00 47.45  ? 29  VAL   A CG1    1 
ATOM   4656 C CG2    . VAL   F 1 17  ? 238.368 265.745 241.080 1.00 41.34  ? 29  VAL   A CG2    1 
ATOM   4657 N N      . GLY   F 1 18  ? 240.349 269.328 243.217 1.00 43.14  ? 30  GLY   A N      1 
ATOM   4658 C CA     . GLY   F 1 18  ? 241.031 270.600 243.379 1.00 43.82  ? 30  GLY   A CA     1 
ATOM   4659 C C      . GLY   F 1 18  ? 242.433 270.442 243.934 1.00 44.43  ? 30  GLY   A C      1 
ATOM   4660 O O      . GLY   F 1 18  ? 243.348 271.174 243.551 1.00 45.11  ? 30  GLY   A O      1 
ATOM   4661 N N      . LYS   F 1 19  ? 242.621 269.487 244.846 1.00 45.47  ? 31  LYS   A N      1 
ATOM   4662 C CA     . LYS   F 1 19  ? 243.955 269.230 245.373 1.00 44.60  ? 31  LYS   A CA     1 
ATOM   4663 C C      . LYS   F 1 19  ? 244.880 268.689 244.292 1.00 44.09  ? 31  LYS   A C      1 
ATOM   4664 O O      . LYS   F 1 19  ? 246.075 269.000 244.287 1.00 43.05  ? 31  LYS   A O      1 
ATOM   4665 C CB     . LYS   F 1 19  ? 243.871 268.262 246.553 1.00 45.21  ? 31  LYS   A CB     1 
ATOM   4666 C CG     . LYS   F 1 19  ? 245.197 267.987 247.232 1.00 50.63  ? 31  LYS   A CG     1 
ATOM   4667 C CD     . LYS   F 1 19  ? 245.001 267.674 248.706 1.00 48.71  ? 31  LYS   A CD     1 
ATOM   4668 C CE     . LYS   F 1 19  ? 244.614 266.224 248.918 1.00 51.21  ? 31  LYS   A CE     1 
ATOM   4669 N NZ     . LYS   F 1 19  ? 245.241 265.335 247.906 1.00 55.24  ? 31  LYS   A NZ     1 
ATOM   4670 N N      . MET   F 1 20  ? 244.345 267.886 243.369 1.00 45.00  ? 32  MET   A N      1 
ATOM   4671 C CA     . MET   F 1 20  ? 245.142 267.419 242.240 1.00 45.05  ? 32  MET   A CA     1 
ATOM   4672 C C      . MET   F 1 20  ? 245.557 268.578 241.343 1.00 44.77  ? 32  MET   A C      1 
ATOM   4673 O O      . MET   F 1 20  ? 246.717 268.667 240.927 1.00 43.10  ? 32  MET   A O      1 
ATOM   4674 C CB     . MET   F 1 20  ? 244.355 266.383 241.438 1.00 44.61  ? 32  MET   A CB     1 
ATOM   4675 C CG     . MET   F 1 20  ? 244.922 266.115 240.058 1.00 46.01  ? 32  MET   A CG     1 
ATOM   4676 S SD     . MET   F 1 20  ? 243.647 265.908 238.801 1.00 55.23  ? 32  MET   A SD     1 
ATOM   4677 C CE     . MET   F 1 20  ? 242.933 264.344 239.287 1.00 44.30  ? 32  MET   A CE     1 
ATOM   4678 N N      . ILE   F 1 21  ? 244.619 269.476 241.035 1.00 44.74  ? 33  ILE   A N      1 
ATOM   4679 C CA     . ILE   F 1 21  ? 244.934 270.620 240.184 1.00 45.21  ? 33  ILE   A CA     1 
ATOM   4680 C C      . ILE   F 1 21  ? 245.910 271.552 240.888 1.00 46.07  ? 33  ILE   A C      1 
ATOM   4681 O O      . ILE   F 1 21  ? 246.813 272.118 240.260 1.00 46.72  ? 33  ILE   A O      1 
ATOM   4682 C CB     . ILE   F 1 21  ? 243.644 271.353 239.776 1.00 45.06  ? 33  ILE   A CB     1 
ATOM   4683 C CG1    . ILE   F 1 21  ? 242.754 270.437 238.937 1.00 42.59  ? 33  ILE   A CG1    1 
ATOM   4684 C CG2    . ILE   F 1 21  ? 243.976 272.611 238.999 1.00 45.19  ? 33  ILE   A CG2    1 
ATOM   4685 C CD1    . ILE   F 1 21  ? 243.510 269.607 237.935 1.00 48.38  ? 33  ILE   A CD1    1 
ATOM   4686 N N      . ASP   F 1 22  ? 245.744 271.729 242.201 1.00 46.24  ? 34  ASP   A N      1 
ATOM   4687 C CA     . ASP   F 1 22  ? 246.686 272.542 242.962 1.00 46.52  ? 34  ASP   A CA     1 
ATOM   4688 C C      . ASP   F 1 22  ? 248.091 271.966 242.887 1.00 46.63  ? 34  ASP   A C      1 
ATOM   4689 O O      . ASP   F 1 22  ? 249.068 272.709 242.738 1.00 47.78  ? 34  ASP   A O      1 
ATOM   4690 C CB     . ASP   F 1 22  ? 246.233 272.654 244.417 1.00 48.01  ? 34  ASP   A CB     1 
ATOM   4691 C CG     . ASP   F 1 22  ? 245.631 274.002 244.735 1.00 52.97  ? 34  ASP   A CG     1 
ATOM   4692 O OD1    . ASP   F 1 22  ? 245.429 274.798 243.796 1.00 57.52  ? 34  ASP   A OD1    1 
ATOM   4693 O OD2    . ASP   F 1 22  ? 245.365 274.269 245.924 1.00 54.17  ? 34  ASP   A OD2    1 
ATOM   4694 N N      . GLY   F 1 23  ? 248.213 270.643 242.997 1.00 46.16  ? 35  GLY   A N      1 
ATOM   4695 C CA     . GLY   F 1 23  ? 249.515 270.019 242.829 1.00 44.70  ? 35  GLY   A CA     1 
ATOM   4696 C C      . GLY   F 1 23  ? 250.091 270.256 241.447 1.00 44.04  ? 35  GLY   A C      1 
ATOM   4697 O O      . GLY   F 1 23  ? 251.280 270.541 241.295 1.00 45.26  ? 35  GLY   A O      1 
ATOM   4698 N N      . ILE   F 1 24  ? 249.250 270.143 240.417 1.00 43.65  ? 36  ILE   A N      1 
ATOM   4699 C CA     . ILE   F 1 24  ? 249.709 270.396 239.054 1.00 45.09  ? 36  ILE   A CA     1 
ATOM   4700 C C      . ILE   F 1 24  ? 250.163 271.843 238.912 1.00 46.72  ? 36  ILE   A C      1 
ATOM   4701 O O      . ILE   F 1 24  ? 251.215 272.129 238.328 1.00 49.18  ? 36  ILE   A O      1 
ATOM   4702 C CB     . ILE   F 1 24  ? 248.602 270.054 238.041 1.00 45.96  ? 36  ILE   A CB     1 
ATOM   4703 C CG1    . ILE   F 1 24  ? 248.345 268.549 238.014 1.00 45.62  ? 36  ILE   A CG1    1 
ATOM   4704 C CG2    . ILE   F 1 24  ? 248.988 270.539 236.659 1.00 48.25  ? 36  ILE   A CG2    1 
ATOM   4705 C CD1    . ILE   F 1 24  ? 247.663 268.077 236.757 1.00 43.42  ? 36  ILE   A CD1    1 
ATOM   4706 N N      . GLY   F 1 25  ? 249.368 272.778 239.433 1.00 44.38  ? 37  GLY   A N      1 
ATOM   4707 C CA     . GLY   F 1 25  ? 249.750 274.178 239.364 1.00 42.63  ? 37  GLY   A CA     1 
ATOM   4708 C C      . GLY   F 1 25  ? 250.976 274.495 240.197 1.00 44.38  ? 37  GLY   A C      1 
ATOM   4709 O O      . GLY   F 1 25  ? 251.878 275.204 239.744 1.00 48.29  ? 37  GLY   A O      1 
ATOM   4710 N N      . ARG   F 1 26  ? 251.030 273.972 241.423 1.00 46.39  ? 38  ARG   A N      1 
ATOM   4711 C CA     . ARG   F 1 26  ? 252.178 274.236 242.283 1.00 46.58  ? 38  ARG   A CA     1 
ATOM   4712 C C      . ARG   F 1 26  ? 253.459 273.690 241.669 1.00 45.95  ? 38  ARG   A C      1 
ATOM   4713 O O      . ARG   F 1 26  ? 254.510 274.337 241.725 1.00 42.18  ? 38  ARG   A O      1 
ATOM   4714 C CB     . ARG   F 1 26  ? 251.954 273.630 243.667 1.00 45.81  ? 38  ARG   A CB     1 
ATOM   4715 C CG     . ARG   F 1 26  ? 252.068 274.625 244.804 1.00 45.93  ? 38  ARG   A CG     1 
ATOM   4716 C CD     . ARG   F 1 26  ? 250.915 274.496 245.782 1.00 43.64  ? 38  ARG   A CD     1 
ATOM   4717 N NE     . ARG   F 1 26  ? 250.662 273.109 246.152 1.00 44.19  ? 38  ARG   A NE     1 
ATOM   4718 C CZ     . ARG   F 1 26  ? 249.537 272.674 246.700 1.00 48.50  ? 38  ARG   A CZ     1 
ATOM   4719 N NH1    . ARG   F 1 26  ? 248.535 273.495 246.963 1.00 48.40  ? 38  ARG   A NH1    1 
ATOM   4720 N NH2    . ARG   F 1 26  ? 249.415 271.384 246.996 1.00 52.42  ? 38  ARG   A NH2    1 
ATOM   4721 N N      . PHE   F 1 27  ? 253.394 272.491 241.088 1.00 46.02  ? 39  PHE   A N      1 
ATOM   4722 C CA     . PHE   F 1 27  ? 254.592 271.898 240.509 1.00 47.93  ? 39  PHE   A CA     1 
ATOM   4723 C C      . PHE   F 1 27  ? 255.063 272.694 239.298 1.00 45.75  ? 39  PHE   A C      1 
ATOM   4724 O O      . PHE   F 1 27  ? 256.268 272.897 239.108 1.00 48.65  ? 39  PHE   A O      1 
ATOM   4725 C CB     . PHE   F 1 27  ? 254.327 270.445 240.122 1.00 44.00  ? 39  PHE   A CB     1 
ATOM   4726 C CG     . PHE   F 1 27  ? 255.166 269.971 238.981 1.00 44.90  ? 39  PHE   A CG     1 
ATOM   4727 C CD1    . PHE   F 1 27  ? 256.498 269.664 239.181 1.00 45.96  ? 39  PHE   A CD1    1 
ATOM   4728 C CD2    . PHE   F 1 27  ? 254.641 269.857 237.709 1.00 44.71  ? 39  PHE   A CD2    1 
ATOM   4729 C CE1    . PHE   F 1 27  ? 257.285 269.231 238.145 1.00 44.04  ? 39  PHE   A CE1    1 
ATOM   4730 C CE2    . PHE   F 1 27  ? 255.428 269.428 236.666 1.00 45.48  ? 39  PHE   A CE2    1 
ATOM   4731 C CZ     . PHE   F 1 27  ? 256.754 269.119 236.888 1.00 44.21  ? 39  PHE   A CZ     1 
ATOM   4732 N N      . TYR   F 1 28  ? 254.126 273.149 238.464 1.00 44.60  ? 40  TYR   A N      1 
ATOM   4733 C CA     . TYR   F 1 28  ? 254.502 273.942 237.298 1.00 45.34  ? 40  TYR   A CA     1 
ATOM   4734 C C      . TYR   F 1 28  ? 255.170 275.245 237.713 1.00 46.89  ? 40  TYR   A C      1 
ATOM   4735 O O      . TYR   F 1 28  ? 256.142 275.681 237.086 1.00 50.26  ? 40  TYR   A O      1 
ATOM   4736 C CB     . TYR   F 1 28  ? 253.275 274.226 236.433 1.00 46.81  ? 40  TYR   A CB     1 
ATOM   4737 C CG     . TYR   F 1 28  ? 253.614 274.847 235.100 1.00 44.60  ? 40  TYR   A CG     1 
ATOM   4738 C CD1    . TYR   F 1 28  ? 254.011 274.061 234.029 1.00 46.30  ? 40  TYR   A CD1    1 
ATOM   4739 C CD2    . TYR   F 1 28  ? 253.556 276.220 234.917 1.00 43.13  ? 40  TYR   A CD2    1 
ATOM   4740 C CE1    . TYR   F 1 28  ? 254.327 274.623 232.811 1.00 46.56  ? 40  TYR   A CE1    1 
ATOM   4741 C CE2    . TYR   F 1 28  ? 253.871 276.791 233.703 1.00 44.11  ? 40  TYR   A CE2    1 
ATOM   4742 C CZ     . TYR   F 1 28  ? 254.256 275.988 232.653 1.00 45.62  ? 40  TYR   A CZ     1 
ATOM   4743 O OH     . TYR   F 1 28  ? 254.572 276.551 231.441 1.00 47.90  ? 40  TYR   A OH     1 
ATOM   4744 N N      . ILE   F 1 29  ? 254.658 275.883 238.765 1.00 48.36  ? 41  ILE   A N      1 
ATOM   4745 C CA     . ILE   F 1 29  ? 255.253 277.126 239.245 1.00 47.85  ? 41  ILE   A CA     1 
ATOM   4746 C C      . ILE   F 1 29  ? 256.699 276.889 239.659 1.00 46.60  ? 41  ILE   A C      1 
ATOM   4747 O O      . ILE   F 1 29  ? 257.599 277.666 239.319 1.00 40.90  ? 41  ILE   A O      1 
ATOM   4748 C CB     . ILE   F 1 29  ? 254.423 277.700 240.407 1.00 44.74  ? 41  ILE   A CB     1 
ATOM   4749 C CG1    . ILE   F 1 29  ? 253.256 278.529 239.875 1.00 44.80  ? 41  ILE   A CG1    1 
ATOM   4750 C CG2    . ILE   F 1 29  ? 255.296 278.541 241.320 1.00 50.33  ? 41  ILE   A CG2    1 
ATOM   4751 C CD1    . ILE   F 1 29  ? 252.339 279.038 240.957 1.00 48.94  ? 41  ILE   A CD1    1 
ATOM   4752 N N      . GLN   F 1 30  ? 256.942 275.806 240.400 1.00 47.81  ? 42  GLN   A N      1 
ATOM   4753 C CA     . GLN   F 1 30  ? 258.296 275.503 240.850 1.00 47.57  ? 42  GLN   A CA     1 
ATOM   4754 C C      . GLN   F 1 30  ? 259.219 275.216 239.675 1.00 50.43  ? 42  GLN   A C      1 
ATOM   4755 O O      . GLN   F 1 30  ? 260.357 275.699 239.637 1.00 54.56  ? 42  GLN   A O      1 
ATOM   4756 C CB     . GLN   F 1 30  ? 258.271 274.320 241.817 1.00 48.91  ? 42  GLN   A CB     1 
ATOM   4757 C CG     . GLN   F 1 30  ? 259.645 273.845 242.244 1.00 48.18  ? 42  GLN   A CG     1 
ATOM   4758 C CD     . GLN   F 1 30  ? 260.351 274.846 243.130 1.00 47.85  ? 42  GLN   A CD     1 
ATOM   4759 O OE1    . GLN   F 1 30  ? 259.715 275.594 243.869 1.00 53.83  ? 42  GLN   A OE1    1 
ATOM   4760 N NE2    . GLN   F 1 30  ? 261.675 274.869 243.057 1.00 48.62  ? 42  GLN   A NE2    1 
ATOM   4761 N N      . MET   F 1 31  ? 258.748 274.435 238.702 1.00 49.56  ? 43  MET   A N      1 
ATOM   4762 C CA     . MET   F 1 31  ? 259.596 274.091 237.567 1.00 46.81  ? 43  MET   A CA     1 
ATOM   4763 C C      . MET   F 1 31  ? 259.863 275.309 236.692 1.00 47.90  ? 43  MET   A C      1 
ATOM   4764 O O      . MET   F 1 31  ? 260.946 275.437 236.111 1.00 49.72  ? 43  MET   A O      1 
ATOM   4765 C CB     . MET   F 1 31  ? 258.957 272.967 236.755 1.00 46.13  ? 43  MET   A CB     1 
ATOM   4766 C CG     . MET   F 1 31  ? 259.487 271.589 237.110 1.00 50.49  ? 43  MET   A CG     1 
ATOM   4767 S SD     . MET   F 1 31  ? 260.868 271.051 236.089 1.00 57.93  ? 43  MET   A SD     1 
ATOM   4768 C CE     . MET   F 1 31  ? 260.005 270.215 234.765 1.00 55.58  ? 43  MET   A CE     1 
ATOM   4769 N N      . CYS   F 1 32  ? 258.887 276.212 236.580 1.00 51.58  ? 44  CYS   A N      1 
ATOM   4770 C CA     . CYS   F 1 32  ? 259.124 277.460 235.862 1.00 50.72  ? 44  CYS   A CA     1 
ATOM   4771 C C      . CYS   F 1 32  ? 260.161 278.315 236.575 1.00 51.59  ? 44  CYS   A C      1 
ATOM   4772 O O      . CYS   F 1 32  ? 261.072 278.859 235.941 1.00 50.14  ? 44  CYS   A O      1 
ATOM   4773 C CB     . CYS   F 1 32  ? 257.816 278.231 235.697 1.00 45.99  ? 44  CYS   A CB     1 
ATOM   4774 S SG     . CYS   F 1 32  ? 256.990 277.941 234.122 1.00 63.41  ? 44  CYS   A SG     1 
ATOM   4775 N N      . THR   F 1 33  ? 260.038 278.447 237.896 1.00 54.03  ? 45  THR   A N      1 
ATOM   4776 C CA     . THR   F 1 33  ? 261.028 279.166 238.687 1.00 51.60  ? 45  THR   A CA     1 
ATOM   4777 C C      . THR   F 1 33  ? 262.377 278.464 238.703 1.00 51.09  ? 45  THR   A C      1 
ATOM   4778 O O      . THR   F 1 33  ? 263.404 279.126 238.886 1.00 53.12  ? 45  THR   A O      1 
ATOM   4779 C CB     . THR   F 1 33  ? 260.526 279.337 240.124 1.00 52.59  ? 45  THR   A CB     1 
ATOM   4780 O OG1    . THR   F 1 33  ? 259.614 280.440 240.191 1.00 59.24  ? 45  THR   A OG1    1 
ATOM   4781 C CG2    . THR   F 1 33  ? 261.686 279.587 241.072 1.00 50.83  ? 45  THR   A CG2    1 
ATOM   4782 N N      . GLU   F 1 34  ? 262.397 277.151 238.503 1.00 51.43  ? 46  GLU   A N      1 
ATOM   4783 C CA     . GLU   F 1 34  ? 263.620 276.367 238.563 1.00 51.06  ? 46  GLU   A CA     1 
ATOM   4784 C C      . GLU   F 1 34  ? 264.249 276.166 237.191 1.00 53.75  ? 46  GLU   A C      1 
ATOM   4785 O O      . GLU   F 1 34  ? 265.455 275.911 237.098 1.00 55.73  ? 46  GLU   A O      1 
ATOM   4786 C CB     . GLU   F 1 34  ? 263.321 275.030 239.239 1.00 49.46  ? 46  GLU   A CB     1 
ATOM   4787 C CG     . GLU   F 1 34  ? 264.405 274.005 239.162 1.00 52.95  ? 46  GLU   A CG     1 
ATOM   4788 C CD     . GLU   F 1 34  ? 263.963 272.771 238.413 1.00 65.40  ? 46  GLU   A CD     1 
ATOM   4789 O OE1    . GLU   F 1 34  ? 262.779 272.699 238.007 1.00 67.35  ? 46  GLU   A OE1    1 
ATOM   4790 O OE2    . GLU   F 1 34  ? 264.792 271.860 238.281 1.00 71.91  ? 46  GLU   A OE2    1 
ATOM   4791 N N      . LEU   F 1 35  ? 263.463 276.280 236.124 1.00 57.78  ? 47  LEU   A N      1 
ATOM   4792 C CA     . LEU   F 1 35  ? 263.989 276.389 234.771 1.00 53.09  ? 47  LEU   A CA     1 
ATOM   4793 C C      . LEU   F 1 35  ? 264.269 277.830 234.366 1.00 53.16  ? 47  LEU   A C      1 
ATOM   4794 O O      . LEU   F 1 35  ? 264.809 278.059 233.280 1.00 56.24  ? 47  LEU   A O      1 
ATOM   4795 C CB     . LEU   F 1 35  ? 263.019 275.756 233.773 1.00 51.92  ? 47  LEU   A CB     1 
ATOM   4796 C CG     . LEU   F 1 35  ? 263.170 274.262 233.502 1.00 54.38  ? 47  LEU   A CG     1 
ATOM   4797 C CD1    . LEU   F 1 35  ? 261.933 273.746 232.804 1.00 52.33  ? 47  LEU   A CD1    1 
ATOM   4798 C CD2    . LEU   F 1 35  ? 264.402 274.000 232.655 1.00 56.56  ? 47  LEU   A CD2    1 
ATOM   4799 N N      . LYS   F 1 36  ? 263.924 278.798 235.214 1.00 53.94  ? 48  LYS   A N      1 
ATOM   4800 C CA     . LYS   F 1 36  ? 264.159 280.216 234.950 1.00 53.13  ? 48  LYS   A CA     1 
ATOM   4801 C C      . LYS   F 1 36  ? 263.456 280.655 233.664 1.00 55.40  ? 48  LYS   A C      1 
ATOM   4802 O O      . LYS   F 1 36  ? 264.080 281.064 232.685 1.00 58.82  ? 48  LYS   A O      1 
ATOM   4803 C CB     . LYS   F 1 36  ? 265.660 280.517 234.893 1.00 53.20  ? 48  LYS   A CB     1 
ATOM   4804 C CG     . LYS   F 1 36  ? 266.026 281.921 235.339 1.00 56.87  ? 48  LYS   A CG     1 
ATOM   4805 C CD     . LYS   F 1 36  ? 266.059 282.023 236.854 1.00 58.21  ? 48  LYS   A CD     1 
ATOM   4806 C CE     . LYS   F 1 36  ? 267.000 280.997 237.459 1.00 49.44  ? 48  LYS   A CE     1 
ATOM   4807 N NZ     . LYS   F 1 36  ? 268.274 280.896 236.701 1.00 47.82  ? 48  LYS   A NZ     1 
ATOM   4808 N N      . LEU   F 1 37  ? 262.130 280.557 233.684 1.00 56.68  ? 49  LEU   A N      1 
ATOM   4809 C CA     . LEU   F 1 37  ? 261.290 280.961 232.565 1.00 54.41  ? 49  LEU   A CA     1 
ATOM   4810 C C      . LEU   F 1 37  ? 260.543 282.233 232.932 1.00 57.34  ? 49  LEU   A C      1 
ATOM   4811 O O      . LEU   F 1 37  ? 260.002 282.343 234.037 1.00 62.05  ? 49  LEU   A O      1 
ATOM   4812 C CB     . LEU   F 1 37  ? 260.299 279.857 232.187 1.00 50.62  ? 49  LEU   A CB     1 
ATOM   4813 C CG     . LEU   F 1 37  ? 260.881 278.532 231.693 1.00 51.15  ? 49  LEU   A CG     1 
ATOM   4814 C CD1    . LEU   F 1 37  ? 259.918 277.394 231.968 1.00 51.60  ? 49  LEU   A CD1    1 
ATOM   4815 C CD2    . LEU   F 1 37  ? 261.211 278.606 230.216 1.00 54.15  ? 49  LEU   A CD2    1 
ATOM   4816 N N      . SER   F 1 38  ? 260.510 283.185 232.008 1.00 55.49  ? 50  SER   A N      1 
ATOM   4817 C CA     . SER   F 1 38  ? 259.845 284.457 232.252 1.00 53.84  ? 50  SER   A CA     1 
ATOM   4818 C C      . SER   F 1 38  ? 258.333 284.257 232.172 1.00 55.79  ? 50  SER   A C      1 
ATOM   4819 O O      . SER   F 1 38  ? 257.838 283.155 231.921 1.00 60.69  ? 50  SER   A O      1 
ATOM   4820 C CB     . SER   F 1 38  ? 260.346 285.509 231.269 1.00 52.75  ? 50  SER   A CB     1 
ATOM   4821 O OG     . SER   F 1 38  ? 259.800 285.303 229.980 1.00 59.20  ? 50  SER   A OG     1 
ATOM   4822 N N      . ASP   F 1 39  ? 257.576 285.331 232.392 1.00 54.09  ? 51  ASP   A N      1 
ATOM   4823 C CA     . ASP   F 1 39  ? 256.121 285.219 232.381 1.00 56.12  ? 51  ASP   A CA     1 
ATOM   4824 C C      . ASP   F 1 39  ? 255.611 284.813 231.004 1.00 55.27  ? 51  ASP   A C      1 
ATOM   4825 O O      . ASP   F 1 39  ? 254.715 283.969 230.888 1.00 57.69  ? 51  ASP   A O      1 
ATOM   4826 C CB     . ASP   F 1 39  ? 255.492 286.538 232.827 1.00 56.69  ? 51  ASP   A CB     1 
ATOM   4827 C CG     . ASP   F 1 39  ? 254.033 286.388 233.197 1.00 59.80  ? 51  ASP   A CG     1 
ATOM   4828 O OD1    . ASP   F 1 39  ? 253.353 287.419 233.367 1.00 59.98  ? 51  ASP   A OD1    1 
ATOM   4829 O OD2    . ASP   F 1 39  ? 253.567 285.238 233.321 1.00 64.28  ? 51  ASP   A OD2    1 
ATOM   4830 N N      . TYR   F 1 40  ? 256.166 285.406 229.946 1.00 51.15  ? 52  TYR   A N      1 
ATOM   4831 C CA     . TYR   F 1 40  ? 255.756 285.031 228.597 1.00 52.04  ? 52  TYR   A CA     1 
ATOM   4832 C C      . TYR   F 1 40  ? 256.126 283.590 228.277 1.00 53.92  ? 52  TYR   A C      1 
ATOM   4833 O O      . TYR   F 1 40  ? 255.284 282.818 227.805 1.00 53.35  ? 52  TYR   A O      1 
ATOM   4834 C CB     . TYR   F 1 40  ? 256.387 285.971 227.573 1.00 58.55  ? 52  TYR   A CB     1 
ATOM   4835 C CG     . TYR   F 1 40  ? 255.597 286.091 226.294 1.00 56.53  ? 52  TYR   A CG     1 
ATOM   4836 C CD1    . TYR   F 1 40  ? 254.535 286.974 226.189 1.00 57.30  ? 52  TYR   A CD1    1 
ATOM   4837 C CD2    . TYR   F 1 40  ? 255.908 285.308 225.194 1.00 55.33  ? 52  TYR   A CD2    1 
ATOM   4838 C CE1    . TYR   F 1 40  ? 253.811 287.080 225.020 1.00 58.26  ? 52  TYR   A CE1    1 
ATOM   4839 C CE2    . TYR   F 1 40  ? 255.190 285.406 224.023 1.00 56.26  ? 52  TYR   A CE2    1 
ATOM   4840 C CZ     . TYR   F 1 40  ? 254.143 286.293 223.941 1.00 56.59  ? 52  TYR   A CZ     1 
ATOM   4841 O OH     . TYR   F 1 40  ? 253.426 286.393 222.773 1.00 57.45  ? 52  TYR   A OH     1 
ATOM   4842 N N      . GLU   F 1 41  ? 257.378 283.208 228.529 1.00 54.07  ? 53  GLU   A N      1 
ATOM   4843 C CA     . GLU   F 1 41  ? 257.823 281.867 228.170 1.00 49.53  ? 53  GLU   A CA     1 
ATOM   4844 C C      . GLU   F 1 41  ? 257.094 280.808 228.985 1.00 49.70  ? 53  GLU   A C      1 
ATOM   4845 O O      . GLU   F 1 41  ? 256.824 279.711 228.485 1.00 53.93  ? 53  GLU   A O      1 
ATOM   4846 C CB     . GLU   F 1 41  ? 259.334 281.748 228.353 1.00 50.80  ? 53  GLU   A CB     1 
ATOM   4847 C CG     . GLU   F 1 41  ? 260.106 282.976 227.913 1.00 56.63  ? 53  GLU   A CG     1 
ATOM   4848 C CD     . GLU   F 1 41  ? 261.466 283.064 228.566 1.00 62.40  ? 53  GLU   A CD     1 
ATOM   4849 O OE1    . GLU   F 1 41  ? 262.246 282.103 228.436 1.00 64.20  ? 53  GLU   A OE1    1 
ATOM   4850 O OE2    . GLU   F 1 41  ? 261.754 284.094 229.210 1.00 63.81  ? 53  GLU   A OE2    1 
ATOM   4851 N N      . GLY   F 1 42  ? 256.773 281.116 230.241 1.00 50.22  ? 54  GLY   A N      1 
ATOM   4852 C CA     . GLY   F 1 42  ? 256.034 280.167 231.056 1.00 48.70  ? 54  GLY   A CA     1 
ATOM   4853 C C      . GLY   F 1 42  ? 254.649 279.885 230.510 1.00 49.73  ? 54  GLY   A C      1 
ATOM   4854 O O      . GLY   F 1 42  ? 254.124 278.779 230.666 1.00 54.20  ? 54  GLY   A O      1 
ATOM   4855 N N      . ARG   F 1 43  ? 254.040 280.873 229.863 1.00 47.22  ? 55  ARG   A N      1 
ATOM   4856 C CA     . ARG   F 1 43  ? 252.703 280.729 229.306 1.00 47.58  ? 55  ARG   A CA     1 
ATOM   4857 C C      . ARG   F 1 43  ? 252.703 280.124 227.909 1.00 50.24  ? 55  ARG   A C      1 
ATOM   4858 O O      . ARG   F 1 43  ? 251.629 279.950 227.326 1.00 53.43  ? 55  ARG   A O      1 
ATOM   4859 C CB     . ARG   F 1 43  ? 251.994 282.085 229.284 1.00 46.61  ? 55  ARG   A CB     1 
ATOM   4860 C CG     . ARG   F 1 43  ? 251.714 282.647 230.666 1.00 47.33  ? 55  ARG   A CG     1 
ATOM   4861 C CD     . ARG   F 1 43  ? 251.301 284.103 230.600 1.00 52.20  ? 55  ARG   A CD     1 
ATOM   4862 N NE     . ARG   F 1 43  ? 251.019 284.647 231.922 1.00 51.57  ? 55  ARG   A NE     1 
ATOM   4863 C CZ     . ARG   F 1 43  ? 249.889 284.453 232.586 1.00 50.33  ? 55  ARG   A CZ     1 
ATOM   4864 N NH1    . ARG   F 1 43  ? 248.911 283.720 232.084 1.00 52.23  ? 55  ARG   A NH1    1 
ATOM   4865 N NH2    . ARG   F 1 43  ? 249.739 285.007 233.784 1.00 54.34  ? 55  ARG   A NH2    1 
ATOM   4866 N N      . LEU   F 1 44  ? 253.871 279.811 227.356 1.00 49.26  ? 56  LEU   A N      1 
ATOM   4867 C CA     . LEU   F 1 44  ? 253.933 279.163 226.054 1.00 48.41  ? 56  LEU   A CA     1 
ATOM   4868 C C      . LEU   F 1 44  ? 253.454 277.722 226.162 1.00 46.95  ? 56  LEU   A C      1 
ATOM   4869 O O      . LEU   F 1 44  ? 253.873 276.984 227.058 1.00 47.45  ? 56  LEU   A O      1 
ATOM   4870 C CB     . LEU   F 1 44  ? 255.358 279.208 225.508 1.00 47.31  ? 56  LEU   A CB     1 
ATOM   4871 C CG     . LEU   F 1 44  ? 255.515 279.168 223.990 1.00 44.51  ? 56  LEU   A CG     1 
ATOM   4872 C CD1    . LEU   F 1 44  ? 255.044 280.470 223.373 1.00 49.80  ? 56  LEU   A CD1    1 
ATOM   4873 C CD2    . LEU   F 1 44  ? 256.959 278.891 223.621 1.00 46.29  ? 56  LEU   A CD2    1 
ATOM   4874 N N      . ILE   F 1 45  ? 252.578 277.319 225.241 1.00 46.43  ? 57  ILE   A N      1 
ATOM   4875 C CA     . ILE   F 1 45  ? 252.048 275.961 225.285 1.00 45.78  ? 57  ILE   A CA     1 
ATOM   4876 C C      . ILE   F 1 45  ? 253.143 274.945 224.992 1.00 45.42  ? 57  ILE   A C      1 
ATOM   4877 O O      . ILE   F 1 45  ? 253.112 273.824 225.511 1.00 45.17  ? 57  ILE   A O      1 
ATOM   4878 C CB     . ILE   F 1 45  ? 250.863 275.814 224.314 1.00 43.58  ? 57  ILE   A CB     1 
ATOM   4879 C CG1    . ILE   F 1 45  ? 249.956 274.668 224.760 1.00 43.09  ? 57  ILE   A CG1    1 
ATOM   4880 C CG2    . ILE   F 1 45  ? 251.357 275.586 222.897 1.00 48.43  ? 57  ILE   A CG2    1 
ATOM   4881 C CD1    . ILE   F 1 45  ? 248.686 274.551 223.962 1.00 47.87  ? 57  ILE   A CD1    1 
ATOM   4882 N N      . GLN   F 1 46  ? 254.122 275.309 224.162 1.00 46.87  ? 58  GLN   A N      1 
ATOM   4883 C CA     . GLN   F 1 46  ? 255.224 274.397 223.875 1.00 46.49  ? 58  GLN   A CA     1 
ATOM   4884 C C      . GLN   F 1 46  ? 256.042 274.106 225.127 1.00 46.09  ? 58  GLN   A C      1 
ATOM   4885 O O      . GLN   F 1 46  ? 256.454 272.963 225.353 1.00 43.98  ? 58  GLN   A O      1 
ATOM   4886 C CB     . GLN   F 1 46  ? 256.112 274.978 222.776 1.00 46.98  ? 58  GLN   A CB     1 
ATOM   4887 C CG     . GLN   F 1 46  ? 255.631 274.688 221.367 1.00 43.49  ? 58  GLN   A CG     1 
ATOM   4888 C CD     . GLN   F 1 46  ? 254.390 275.473 221.003 1.00 44.31  ? 58  GLN   A CD     1 
ATOM   4889 O OE1    . GLN   F 1 46  ? 254.101 276.510 221.597 1.00 46.97  ? 58  GLN   A OE1    1 
ATOM   4890 N NE2    . GLN   F 1 46  ? 253.649 274.983 220.020 1.00 44.63  ? 58  GLN   A NE2    1 
ATOM   4891 N N      . ASN   F 1 47  ? 256.299 275.129 225.945 1.00 47.43  ? 59  ASN   A N      1 
ATOM   4892 C CA     . ASN   F 1 47  ? 257.023 274.911 227.193 1.00 46.68  ? 59  ASN   A CA     1 
ATOM   4893 C C      . ASN   F 1 47  ? 256.229 274.027 228.143 1.00 47.63  ? 59  ASN   A C      1 
ATOM   4894 O O      . ASN   F 1 47  ? 256.794 273.148 228.804 1.00 50.48  ? 59  ASN   A O      1 
ATOM   4895 C CB     . ASN   F 1 47  ? 257.346 276.249 227.857 1.00 44.33  ? 59  ASN   A CB     1 
ATOM   4896 C CG     . ASN   F 1 47  ? 258.333 277.072 227.062 1.00 45.48  ? 59  ASN   A CG     1 
ATOM   4897 O OD1    . ASN   F 1 47  ? 258.842 276.630 226.035 1.00 50.10  ? 59  ASN   A OD1    1 
ATOM   4898 N ND2    . ASN   F 1 47  ? 258.610 278.279 227.534 1.00 48.28  ? 59  ASN   A ND2    1 
ATOM   4899 N N      . SER   F 1 48  ? 254.916 274.249 228.229 1.00 45.88  ? 60  SER   A N      1 
ATOM   4900 C CA     . SER   F 1 48  ? 254.092 273.463 229.139 1.00 47.96  ? 60  SER   A CA     1 
ATOM   4901 C C      . SER   F 1 48  ? 254.099 271.990 228.756 1.00 43.65  ? 60  SER   A C      1 
ATOM   4902 O O      . SER   F 1 48  ? 254.176 271.115 229.626 1.00 44.14  ? 60  SER   A O      1 
ATOM   4903 C CB     . SER   F 1 48  ? 252.664 274.007 229.158 1.00 49.62  ? 60  SER   A CB     1 
ATOM   4904 O OG     . SER   F 1 48  ? 251.990 273.712 227.949 1.00 52.60  ? 60  SER   A OG     1 
ATOM   4905 N N      . LEU   F 1 49  ? 254.017 271.694 227.458 1.00 43.81  ? 61  LEU   A N      1 
ATOM   4906 C CA     . LEU   F 1 49  ? 254.074 270.305 227.018 1.00 44.22  ? 61  LEU   A CA     1 
ATOM   4907 C C      . LEU   F 1 49  ? 255.407 269.665 227.386 1.00 43.32  ? 61  LEU   A C      1 
ATOM   4908 O O      . LEU   F 1 49  ? 255.445 268.532 227.876 1.00 44.34  ? 61  LEU   A O      1 
ATOM   4909 C CB     . LEU   F 1 49  ? 253.836 270.220 225.511 1.00 43.94  ? 61  LEU   A CB     1 
ATOM   4910 C CG     . LEU   F 1 49  ? 252.377 270.240 225.056 1.00 43.47  ? 61  LEU   A CG     1 
ATOM   4911 C CD1    . LEU   F 1 49  ? 252.237 271.000 223.751 1.00 46.57  ? 61  LEU   A CD1    1 
ATOM   4912 C CD2    . LEU   F 1 49  ? 251.844 268.828 224.915 1.00 46.38  ? 61  LEU   A CD2    1 
ATOM   4913 N N      . THR   F 1 50  ? 256.511 270.382 227.168 1.00 43.26  ? 62  THR   A N      1 
ATOM   4914 C CA     . THR   F 1 50  ? 257.821 269.834 227.501 1.00 46.08  ? 62  THR   A CA     1 
ATOM   4915 C C      . THR   F 1 50  ? 257.925 269.522 228.988 1.00 45.79  ? 62  THR   A C      1 
ATOM   4916 O O      . THR   F 1 50  ? 258.411 268.454 229.374 1.00 46.59  ? 62  THR   A O      1 
ATOM   4917 C CB     . THR   F 1 50  ? 258.919 270.809 227.081 1.00 48.79  ? 62  THR   A CB     1 
ATOM   4918 O OG1    . THR   F 1 50  ? 259.142 270.699 225.671 1.00 53.50  ? 62  THR   A OG1    1 
ATOM   4919 C CG2    . THR   F 1 50  ? 260.211 270.502 227.816 1.00 51.51  ? 62  THR   A CG2    1 
ATOM   4920 N N      . ILE   F 1 51  ? 257.460 270.440 229.837 1.00 46.15  ? 63  ILE   A N      1 
ATOM   4921 C CA     . ILE   F 1 51  ? 257.488 270.207 231.279 1.00 46.55  ? 63  ILE   A CA     1 
ATOM   4922 C C      . ILE   F 1 51  ? 256.602 269.023 231.644 1.00 44.42  ? 63  ILE   A C      1 
ATOM   4923 O O      . ILE   F 1 51  ? 256.976 268.172 232.459 1.00 42.94  ? 63  ILE   A O      1 
ATOM   4924 C CB     . ILE   F 1 51  ? 257.073 271.482 232.035 1.00 46.41  ? 63  ILE   A CB     1 
ATOM   4925 C CG1    . ILE   F 1 51  ? 257.959 272.656 231.614 1.00 45.63  ? 63  ILE   A CG1    1 
ATOM   4926 C CG2    . ILE   F 1 51  ? 257.148 271.263 233.533 1.00 50.85  ? 63  ILE   A CG2    1 
ATOM   4927 C CD1    . ILE   F 1 51  ? 258.085 273.727 232.663 1.00 48.58  ? 63  ILE   A CD1    1 
ATOM   4928 N N      . GLU   F 1 52  ? 255.411 268.951 231.045 1.00 45.38  ? 64  GLU   A N      1 
ATOM   4929 C CA     . GLU   F 1 52  ? 254.517 267.831 231.320 1.00 43.54  ? 64  GLU   A CA     1 
ATOM   4930 C C      . GLU   F 1 52  ? 255.143 266.511 230.895 1.00 44.84  ? 64  GLU   A C      1 
ATOM   4931 O O      . GLU   F 1 52  ? 255.089 265.523 231.635 1.00 43.73  ? 64  GLU   A O      1 
ATOM   4932 C CB     . GLU   F 1 52  ? 253.181 268.030 230.605 1.00 44.00  ? 64  GLU   A CB     1 
ATOM   4933 C CG     . GLU   F 1 52  ? 252.421 269.267 231.019 1.00 44.63  ? 64  GLU   A CG     1 
ATOM   4934 C CD     . GLU   F 1 52  ? 251.353 269.642 230.016 1.00 50.05  ? 64  GLU   A CD     1 
ATOM   4935 O OE1    . GLU   F 1 52  ? 251.303 269.014 228.940 1.00 50.75  ? 64  GLU   A OE1    1 
ATOM   4936 O OE2    . GLU   F 1 52  ? 250.566 270.566 230.301 1.00 54.20  ? 64  GLU   A OE2    1 
ATOM   4937 N N      . ARG   F 1 53  ? 255.743 266.478 229.703 1.00 47.54  ? 65  ARG   A N      1 
ATOM   4938 C CA     . ARG   F 1 53  ? 256.340 265.243 229.207 1.00 47.17  ? 65  ARG   A CA     1 
ATOM   4939 C C      . ARG   F 1 53  ? 257.518 264.810 230.065 1.00 47.06  ? 65  ARG   A C      1 
ATOM   4940 O O      . ARG   F 1 53  ? 257.771 263.609 230.210 1.00 47.57  ? 65  ARG   A O      1 
ATOM   4941 C CB     . ARG   F 1 53  ? 256.771 265.422 227.752 1.00 46.32  ? 65  ARG   A CB     1 
ATOM   4942 C CG     . ARG   F 1 53  ? 255.644 265.846 226.830 1.00 47.64  ? 65  ARG   A CG     1 
ATOM   4943 C CD     . ARG   F 1 53  ? 256.111 265.976 225.393 1.00 49.67  ? 65  ARG   A CD     1 
ATOM   4944 N NE     . ARG   F 1 53  ? 255.927 264.743 224.639 1.00 44.55  ? 65  ARG   A NE     1 
ATOM   4945 C CZ     . ARG   F 1 53  ? 256.896 264.108 223.995 1.00 51.32  ? 65  ARG   A CZ     1 
ATOM   4946 N NH1    . ARG   F 1 53  ? 258.136 264.566 223.988 1.00 59.77  ? 65  ARG   A NH1    1 
ATOM   4947 N NH2    . ARG   F 1 53  ? 256.612 262.987 223.339 1.00 55.05  ? 65  ARG   A NH2    1 
ATOM   4948 N N      . MET   F 1 54  ? 258.248 265.767 230.640 1.00 46.32  ? 66  MET   A N      1 
ATOM   4949 C CA     . MET   F 1 54  ? 259.359 265.422 231.519 1.00 46.80  ? 66  MET   A CA     1 
ATOM   4950 C C      . MET   F 1 54  ? 258.872 264.675 232.754 1.00 47.96  ? 66  MET   A C      1 
ATOM   4951 O O      . MET   F 1 54  ? 259.487 263.689 233.176 1.00 51.85  ? 66  MET   A O      1 
ATOM   4952 C CB     . MET   F 1 54  ? 260.124 266.683 231.919 1.00 46.57  ? 66  MET   A CB     1 
ATOM   4953 C CG     . MET   F 1 54  ? 261.177 267.108 230.913 1.00 50.46  ? 66  MET   A CG     1 
ATOM   4954 S SD     . MET   F 1 54  ? 261.583 268.861 230.994 1.00 60.24  ? 66  MET   A SD     1 
ATOM   4955 C CE     . MET   F 1 54  ? 262.193 268.989 232.668 1.00 50.18  ? 66  MET   A CE     1 
ATOM   4956 N N      . VAL   F 1 55  ? 257.769 265.131 233.347 1.00 47.69  ? 67  VAL   A N      1 
ATOM   4957 C CA     . VAL   F 1 55  ? 257.250 264.490 234.551 1.00 46.26  ? 67  VAL   A CA     1 
ATOM   4958 C C      . VAL   F 1 55  ? 256.741 263.092 234.236 1.00 46.17  ? 67  VAL   A C      1 
ATOM   4959 O O      . VAL   F 1 55  ? 257.000 262.139 234.980 1.00 47.35  ? 67  VAL   A O      1 
ATOM   4960 C CB     . VAL   F 1 55  ? 256.144 265.356 235.174 1.00 46.98  ? 67  VAL   A CB     1 
ATOM   4961 C CG1    . VAL   F 1 55  ? 255.949 265.001 236.638 1.00 47.32  ? 67  VAL   A CG1    1 
ATOM   4962 C CG2    . VAL   F 1 55  ? 256.466 266.812 234.991 1.00 50.87  ? 67  VAL   A CG2    1 
ATOM   4963 N N      . LEU   F 1 56  ? 256.002 262.949 233.136 1.00 44.54  ? 68  LEU   A N      1 
ATOM   4964 C CA     . LEU   F 1 56  ? 255.433 261.651 232.794 1.00 45.42  ? 68  LEU   A CA     1 
ATOM   4965 C C      . LEU   F 1 56  ? 256.525 260.615 232.572 1.00 47.41  ? 68  LEU   A C      1 
ATOM   4966 O O      . LEU   F 1 56  ? 256.395 259.464 233.002 1.00 52.30  ? 68  LEU   A O      1 
ATOM   4967 C CB     . LEU   F 1 56  ? 254.548 261.779 231.555 1.00 47.53  ? 68  LEU   A CB     1 
ATOM   4968 C CG     . LEU   F 1 56  ? 253.348 262.714 231.690 1.00 45.68  ? 68  LEU   A CG     1 
ATOM   4969 C CD1    . LEU   F 1 56  ? 252.501 262.671 230.434 1.00 44.07  ? 68  LEU   A CD1    1 
ATOM   4970 C CD2    . LEU   F 1 56  ? 252.524 262.348 232.909 1.00 46.67  ? 68  LEU   A CD2    1 
ATOM   4971 N N      . SER   F 1 57  ? 257.611 261.003 231.902 1.00 43.94  ? 69  SER   A N      1 
ATOM   4972 C CA     . SER   F 1 57  ? 258.723 260.085 231.705 1.00 44.18  ? 69  SER   A CA     1 
ATOM   4973 C C      . SER   F 1 57  ? 259.507 259.850 232.988 1.00 46.61  ? 69  SER   A C      1 
ATOM   4974 O O      . SER   F 1 57  ? 260.081 258.771 233.159 1.00 49.55  ? 69  SER   A O      1 
ATOM   4975 C CB     . SER   F 1 57  ? 259.654 260.610 230.612 1.00 45.14  ? 69  SER   A CB     1 
ATOM   4976 O OG     . SER   F 1 57  ? 260.609 261.509 231.143 1.00 49.41  ? 69  SER   A OG     1 
ATOM   4977 N N      . ALA   F 1 58  ? 259.538 260.831 233.892 1.00 45.74  ? 70  ALA   A N      1 
ATOM   4978 C CA     . ALA   F 1 58  ? 260.247 260.652 235.153 1.00 45.21  ? 70  ALA   A CA     1 
ATOM   4979 C C      . ALA   F 1 58  ? 259.583 259.597 236.027 1.00 46.97  ? 70  ALA   A C      1 
ATOM   4980 O O      . ALA   F 1 58  ? 260.252 258.972 236.856 1.00 48.51  ? 70  ALA   A O      1 
ATOM   4981 C CB     . ALA   F 1 58  ? 260.334 261.981 235.900 1.00 42.04  ? 70  ALA   A CB     1 
ATOM   4982 N N      . PHE   F 1 59  ? 258.280 259.390 235.864 1.00 47.16  ? 71  PHE   A N      1 
ATOM   4983 C CA     . PHE   F 1 59  ? 257.533 258.430 236.663 1.00 46.07  ? 71  PHE   A CA     1 
ATOM   4984 C C      . PHE   F 1 59  ? 257.219 257.148 235.904 1.00 49.19  ? 71  PHE   A C      1 
ATOM   4985 O O      . PHE   F 1 59  ? 256.403 256.349 236.370 1.00 54.67  ? 71  PHE   A O      1 
ATOM   4986 C CB     . PHE   F 1 59  ? 256.245 259.072 237.177 1.00 44.73  ? 71  PHE   A CB     1 
ATOM   4987 C CG     . PHE   F 1 59  ? 256.445 259.927 238.393 1.00 42.74  ? 71  PHE   A CG     1 
ATOM   4988 C CD1    . PHE   F 1 59  ? 256.281 259.400 239.661 1.00 43.17  ? 71  PHE   A CD1    1 
ATOM   4989 C CD2    . PHE   F 1 59  ? 256.811 261.253 238.269 1.00 44.62  ? 71  PHE   A CD2    1 
ATOM   4990 C CE1    . PHE   F 1 59  ? 256.469 260.184 240.780 1.00 42.69  ? 71  PHE   A CE1    1 
ATOM   4991 C CE2    . PHE   F 1 59  ? 257.000 262.040 239.385 1.00 47.26  ? 71  PHE   A CE2    1 
ATOM   4992 C CZ     . PHE   F 1 59  ? 256.830 261.504 240.641 1.00 44.15  ? 71  PHE   A CZ     1 
ATOM   4993 N N      . ASP   F 1 60  ? 257.847 256.932 234.751 1.00 48.75  ? 72  ASP   A N      1 
ATOM   4994 C CA     . ASP   F 1 60  ? 257.653 255.709 233.974 1.00 49.93  ? 72  ASP   A CA     1 
ATOM   4995 C C      . ASP   F 1 60  ? 258.632 254.662 234.485 1.00 51.99  ? 72  ASP   A C      1 
ATOM   4996 O O      . ASP   F 1 60  ? 259.739 254.506 233.971 1.00 54.35  ? 72  ASP   A O      1 
ATOM   4997 C CB     . ASP   F 1 60  ? 257.847 255.974 232.487 1.00 49.85  ? 72  ASP   A CB     1 
ATOM   4998 C CG     . ASP   F 1 60  ? 257.196 254.919 231.622 1.00 54.31  ? 72  ASP   A CG     1 
ATOM   4999 O OD1    . ASP   F 1 60  ? 257.006 253.787 232.109 1.00 57.30  ? 72  ASP   A OD1    1 
ATOM   5000 O OD2    . ASP   F 1 60  ? 256.877 255.218 230.455 1.00 57.26  ? 72  ASP   A OD2    1 
ATOM   5001 N N      . GLU   F 1 61  ? 258.211 253.928 235.514 1.00 52.25  ? 73  GLU   A N      1 
ATOM   5002 C CA     . GLU   F 1 61  ? 259.103 252.956 236.137 1.00 51.97  ? 73  GLU   A CA     1 
ATOM   5003 C C      . GLU   F 1 61  ? 259.539 251.882 235.148 1.00 51.98  ? 73  GLU   A C      1 
ATOM   5004 O O      . GLU   F 1 61  ? 260.725 251.540 235.077 1.00 55.72  ? 73  GLU   A O      1 
ATOM   5005 C CB     . GLU   F 1 61  ? 258.417 252.328 237.348 1.00 56.47  ? 73  GLU   A CB     1 
ATOM   5006 C CG     . GLU   F 1 61  ? 259.156 251.148 237.938 1.00 64.91  ? 73  GLU   A CG     1 
ATOM   5007 C CD     . GLU   F 1 61  ? 259.121 251.141 239.449 1.00 74.88  ? 73  GLU   A CD     1 
ATOM   5008 O OE1    . GLU   F 1 61  ? 258.024 251.309 240.019 1.00 74.55  ? 73  GLU   A OE1    1 
ATOM   5009 O OE2    . GLU   F 1 61  ? 260.191 250.964 240.065 1.00 87.03  ? 73  GLU   A OE2    1 
ATOM   5010 N N      . ARG   F 1 62  ? 258.599 251.343 234.368 1.00 49.79  ? 74  ARG   A N      1 
ATOM   5011 C CA     . ARG   F 1 62  ? 258.928 250.239 233.471 1.00 50.77  ? 74  ARG   A CA     1 
ATOM   5012 C C      . ARG   F 1 62  ? 259.914 250.671 232.393 1.00 52.82  ? 74  ARG   A C      1 
ATOM   5013 O O      . ARG   F 1 62  ? 260.929 250.003 232.164 1.00 55.37  ? 74  ARG   A O      1 
ATOM   5014 C CB     . ARG   F 1 62  ? 257.656 249.675 232.841 1.00 49.68  ? 74  ARG   A CB     1 
ATOM   5015 C CG     . ARG   F 1 62  ? 256.901 248.713 233.736 1.00 57.08  ? 74  ARG   A CG     1 
ATOM   5016 C CD     . ARG   F 1 62  ? 255.658 248.174 233.052 1.00 61.51  ? 74  ARG   A CD     1 
ATOM   5017 N NE     . ARG   F 1 62  ? 255.964 247.110 232.105 1.00 61.45  ? 74  ARG   A NE     1 
ATOM   5018 C CZ     . ARG   F 1 62  ? 255.086 246.213 231.679 1.00 66.90  ? 74  ARG   A CZ     1 
ATOM   5019 N NH1    . ARG   F 1 62  ? 253.835 246.214 232.108 1.00 69.33  ? 74  ARG   A NH1    1 
ATOM   5020 N NH2    . ARG   F 1 62  ? 255.471 245.293 230.801 1.00 73.02  ? 74  ARG   A NH2    1 
ATOM   5021 N N      . ARG   F 1 63  ? 259.633 251.784 231.713 1.00 49.20  ? 75  ARG   A N      1 
ATOM   5022 C CA     . ARG   F 1 63  ? 260.531 252.229 230.654 1.00 49.31  ? 75  ARG   A CA     1 
ATOM   5023 C C      . ARG   F 1 63  ? 261.874 252.665 231.223 1.00 51.49  ? 75  ARG   A C      1 
ATOM   5024 O O      . ARG   F 1 63  ? 262.923 252.421 230.617 1.00 52.87  ? 75  ARG   A O      1 
ATOM   5025 C CB     . ARG   F 1 63  ? 259.890 253.361 229.854 1.00 49.40  ? 75  ARG   A CB     1 
ATOM   5026 C CG     . ARG   F 1 63  ? 260.886 254.197 229.077 1.00 49.77  ? 75  ARG   A CG     1 
ATOM   5027 C CD     . ARG   F 1 63  ? 260.200 255.312 228.316 1.00 49.68  ? 75  ARG   A CD     1 
ATOM   5028 N NE     . ARG   F 1 63  ? 261.162 256.195 227.669 1.00 49.58  ? 75  ARG   A NE     1 
ATOM   5029 C CZ     . ARG   F 1 63  ? 261.798 255.912 226.541 1.00 52.18  ? 75  ARG   A CZ     1 
ATOM   5030 N NH1    . ARG   F 1 63  ? 261.598 254.772 225.902 1.00 52.09  ? 75  ARG   A NH1    1 
ATOM   5031 N NH2    . ARG   F 1 63  ? 262.657 256.795 226.042 1.00 52.56  ? 75  ARG   A NH2    1 
ATOM   5032 N N      . ASN   F 1 64  ? 261.862 253.310 232.390 1.00 51.31  ? 76  ASN   A N      1 
ATOM   5033 C CA     . ASN   F 1 64  ? 263.116 253.679 233.036 1.00 50.45  ? 76  ASN   A CA     1 
ATOM   5034 C C      . ASN   F 1 64  ? 263.941 252.444 233.373 1.00 51.27  ? 76  ASN   A C      1 
ATOM   5035 O O      . ASN   F 1 64  ? 265.160 252.428 233.172 1.00 53.64  ? 76  ASN   A O      1 
ATOM   5036 C CB     . ASN   F 1 64  ? 262.837 254.497 234.295 1.00 50.73  ? 76  ASN   A CB     1 
ATOM   5037 C CG     . ASN   F 1 64  ? 262.254 255.856 233.985 1.00 50.89  ? 76  ASN   A CG     1 
ATOM   5038 O OD1    . ASN   F 1 64  ? 262.043 256.204 232.826 1.00 47.10  ? 76  ASN   A OD1    1 
ATOM   5039 N ND2    . ASN   F 1 64  ? 261.988 256.635 235.025 1.00 54.47  ? 76  ASN   A ND2    1 
ATOM   5040 N N      . LYS   F 1 65  ? 263.291 251.397 233.884 1.00 51.81  ? 77  LYS   A N      1 
ATOM   5041 C CA     . LYS   F 1 65  ? 264.001 250.156 234.174 1.00 52.89  ? 77  LYS   A CA     1 
ATOM   5042 C C      . LYS   F 1 65  ? 264.618 249.569 232.913 1.00 54.30  ? 77  LYS   A C      1 
ATOM   5043 O O      . LYS   F 1 65  ? 265.776 249.136 232.922 1.00 56.65  ? 77  LYS   A O      1 
ATOM   5044 C CB     . LYS   F 1 65  ? 263.052 249.149 234.823 1.00 56.16  ? 77  LYS   A CB     1 
ATOM   5045 C CG     . LYS   F 1 65  ? 262.967 249.258 236.330 1.00 62.67  ? 77  LYS   A CG     1 
ATOM   5046 C CD     . LYS   F 1 65  ? 264.347 249.306 236.951 1.00 71.19  ? 77  LYS   A CD     1 
ATOM   5047 C CE     . LYS   F 1 65  ? 265.076 247.992 236.745 1.00 76.99  ? 77  LYS   A CE     1 
ATOM   5048 N NZ     . LYS   F 1 65  ? 264.146 246.835 236.849 1.00 70.27  ? 77  LYS   A NZ     1 
ATOM   5049 N N      . TYR   F 1 66  ? 263.858 249.541 231.817 1.00 51.18  ? 78  TYR   A N      1 
ATOM   5050 C CA     . TYR   F 1 66  ? 264.380 248.992 230.571 1.00 50.76  ? 78  TYR   A CA     1 
ATOM   5051 C C      . TYR   F 1 66  ? 265.530 249.839 230.042 1.00 51.24  ? 78  TYR   A C      1 
ATOM   5052 O O      . TYR   F 1 66  ? 266.511 249.307 229.510 1.00 51.46  ? 78  TYR   A O      1 
ATOM   5053 C CB     . TYR   F 1 66  ? 263.260 248.879 229.537 1.00 47.41  ? 78  TYR   A CB     1 
ATOM   5054 C CG     . TYR   F 1 66  ? 263.664 248.161 228.269 1.00 44.21  ? 78  TYR   A CG     1 
ATOM   5055 C CD1    . TYR   F 1 66  ? 264.342 248.822 227.256 1.00 46.21  ? 78  TYR   A CD1    1 
ATOM   5056 C CD2    . TYR   F 1 66  ? 263.378 246.816 228.093 1.00 45.91  ? 78  TYR   A CD2    1 
ATOM   5057 C CE1    . TYR   F 1 66  ? 264.716 248.165 226.101 1.00 45.24  ? 78  TYR   A CE1    1 
ATOM   5058 C CE2    . TYR   F 1 66  ? 263.749 246.151 226.944 1.00 48.23  ? 78  TYR   A CE2    1 
ATOM   5059 C CZ     . TYR   F 1 66  ? 264.416 246.830 225.953 1.00 49.37  ? 78  TYR   A CZ     1 
ATOM   5060 O OH     . TYR   F 1 66  ? 264.786 246.169 224.805 1.00 58.28  ? 78  TYR   A OH     1 
ATOM   5061 N N      . LEU   F 1 67  ? 265.427 251.161 230.180 1.00 50.91  ? 79  LEU   A N      1 
ATOM   5062 C CA     . LEU   F 1 67  ? 266.518 252.035 229.763 1.00 50.72  ? 79  LEU   A CA     1 
ATOM   5063 C C      . LEU   F 1 67  ? 267.777 251.773 230.579 1.00 53.71  ? 79  LEU   A C      1 
ATOM   5064 O O      . LEU   F 1 67  ? 268.888 251.792 230.038 1.00 57.07  ? 79  LEU   A O      1 
ATOM   5065 C CB     . LEU   F 1 67  ? 266.092 253.495 229.885 1.00 50.34  ? 79  LEU   A CB     1 
ATOM   5066 C CG     . LEU   F 1 67  ? 265.145 254.008 228.804 1.00 48.11  ? 79  LEU   A CG     1 
ATOM   5067 C CD1    . LEU   F 1 67  ? 265.012 255.514 228.895 1.00 46.14  ? 79  LEU   A CD1    1 
ATOM   5068 C CD2    . LEU   F 1 67  ? 265.630 253.590 227.430 1.00 52.56  ? 79  LEU   A CD2    1 
ATOM   5069 N N      . GLU   F 1 68  ? 267.626 251.534 231.884 1.00 54.21  ? 80  GLU   A N      1 
ATOM   5070 C CA     . GLU   F 1 68  ? 268.775 251.168 232.706 1.00 54.91  ? 80  GLU   A CA     1 
ATOM   5071 C C      . GLU   F 1 68  ? 269.402 249.867 232.226 1.00 57.16  ? 80  GLU   A C      1 
ATOM   5072 O O      . GLU   F 1 68  ? 270.613 249.799 231.991 1.00 55.92  ? 80  GLU   A O      1 
ATOM   5073 C CB     . GLU   F 1 68  ? 268.352 251.031 234.168 1.00 59.10  ? 80  GLU   A CB     1 
ATOM   5074 C CG     . GLU   F 1 68  ? 267.638 252.233 234.745 1.00 61.64  ? 80  GLU   A CG     1 
ATOM   5075 C CD     . GLU   F 1 68  ? 268.431 252.901 235.844 1.00 70.73  ? 80  GLU   A CD     1 
ATOM   5076 O OE1    . GLU   F 1 68  ? 269.636 252.605 235.972 1.00 75.03  ? 80  GLU   A OE1    1 
ATOM   5077 O OE2    . GLU   F 1 68  ? 267.848 253.718 236.586 1.00 74.14  ? 80  GLU   A OE2    1 
ATOM   5078 N N      . GLU   F 1 69  ? 268.588 248.820 232.077 1.00 60.33  ? 81  GLU   A N      1 
ATOM   5079 C CA     . GLU   F 1 69  ? 269.115 247.513 231.702 1.00 60.83  ? 81  GLU   A CA     1 
ATOM   5080 C C      . GLU   F 1 69  ? 269.742 247.543 230.315 1.00 61.13  ? 81  GLU   A C      1 
ATOM   5081 O O      . GLU   F 1 69  ? 270.818 246.973 230.101 1.00 63.93  ? 81  GLU   A O      1 
ATOM   5082 C CB     . GLU   F 1 69  ? 268.003 246.467 231.764 1.00 62.08  ? 81  GLU   A CB     1 
ATOM   5083 C CG     . GLU   F 1 69  ? 268.062 245.560 232.978 1.00 70.88  ? 81  GLU   A CG     1 
ATOM   5084 C CD     . GLU   F 1 69  ? 267.920 246.321 234.279 1.00 85.21  ? 81  GLU   A CD     1 
ATOM   5085 O OE1    . GLU   F 1 69  ? 268.262 245.755 235.339 1.00 95.51  ? 81  GLU   A OE1    1 
ATOM   5086 O OE2    . GLU   F 1 69  ? 267.469 247.484 234.242 1.00 81.34  ? 81  GLU   A OE2    1 
ATOM   5087 N N      . HIS   F 1 70  ? 269.088 248.202 229.363 1.00 57.24  ? 82  HIS   A N      1 
ATOM   5088 C CA     . HIS   F 1 70  ? 269.519 248.229 227.966 1.00 53.43  ? 82  HIS   A CA     1 
ATOM   5089 C C      . HIS   F 1 70  ? 269.642 249.684 227.535 1.00 53.98  ? 82  HIS   A C      1 
ATOM   5090 O O      . HIS   F 1 70  ? 268.760 250.220 226.851 1.00 52.85  ? 82  HIS   A O      1 
ATOM   5091 C CB     . HIS   F 1 70  ? 268.542 247.459 227.078 1.00 52.04  ? 82  HIS   A CB     1 
ATOM   5092 C CG     . HIS   F 1 70  ? 268.113 246.145 227.654 1.00 57.22  ? 82  HIS   A CG     1 
ATOM   5093 N ND1    . HIS   F 1 70  ? 266.834 245.652 227.514 1.00 62.87  ? 82  HIS   A ND1    1 
ATOM   5094 C CD2    . HIS   F 1 70  ? 268.797 245.217 228.363 1.00 62.76  ? 82  HIS   A CD2    1 
ATOM   5095 C CE1    . HIS   F 1 70  ? 266.747 244.482 228.119 1.00 63.19  ? 82  HIS   A CE1    1 
ATOM   5096 N NE2    . HIS   F 1 70  ? 267.924 244.195 228.642 1.00 65.58  ? 82  HIS   A NE2    1 
ATOM   5097 N N      . PRO   F 1 71  ? 270.731 250.350 227.909 1.00 55.41  ? 83  PRO   A N      1 
ATOM   5098 C CA     . PRO   F 1 71  ? 270.832 251.791 227.663 1.00 53.92  ? 83  PRO   A CA     1 
ATOM   5099 C C      . PRO   F 1 71  ? 270.816 252.119 226.180 1.00 57.16  ? 83  PRO   A C      1 
ATOM   5100 O O      . PRO   F 1 71  ? 271.299 251.357 225.340 1.00 59.20  ? 83  PRO   A O      1 
ATOM   5101 C CB     . PRO   F 1 71  ? 272.174 252.173 228.298 1.00 48.88  ? 83  PRO   A CB     1 
ATOM   5102 C CG     . PRO   F 1 71  ? 272.941 250.912 228.395 1.00 53.84  ? 83  PRO   A CG     1 
ATOM   5103 C CD     . PRO   F 1 71  ? 271.964 249.782 228.478 1.00 57.11  ? 83  PRO   A CD     1 
ATOM   5104 N N      . SER   F 1 72  ? 270.247 253.279 225.868 1.00 57.53  ? 84  SER   A N      1 
ATOM   5105 C CA     . SER   F 1 72  ? 270.188 253.763 224.497 1.00 55.71  ? 84  SER   A CA     1 
ATOM   5106 C C      . SER   F 1 72  ? 271.543 254.357 224.118 1.00 59.05  ? 84  SER   A C      1 
ATOM   5107 O O      . SER   F 1 72  ? 272.464 254.441 224.935 1.00 59.93  ? 84  SER   A O      1 
ATOM   5108 C CB     . SER   F 1 72  ? 269.049 254.767 224.342 1.00 54.13  ? 84  SER   A CB     1 
ATOM   5109 O OG     . SER   F 1 72  ? 268.874 255.131 222.986 1.00 58.89  ? 84  SER   A OG     1 
ATOM   5110 N N      . ALA   F 1 73  ? 271.680 254.785 222.868 1.00 59.73  ? 85  ALA   A N      1 
ATOM   5111 C CA     . ALA   F 1 73  ? 272.952 255.270 222.347 1.00 57.89  ? 85  ALA   A CA     1 
ATOM   5112 C C      . ALA   F 1 73  ? 273.020 256.781 222.530 1.00 57.83  ? 85  ALA   A C      1 
ATOM   5113 O O      . ALA   F 1 73  ? 272.214 257.521 221.957 1.00 61.71  ? 85  ALA   A O      1 
ATOM   5114 C CB     . ALA   F 1 73  ? 273.114 254.884 220.879 1.00 62.25  ? 85  ALA   A CB     1 
ATOM   5115 N N      . GLY   F 1 74  ? 273.979 257.237 223.330 1.00 53.77  ? 86  GLY   A N      1 
ATOM   5116 C CA     . GLY   F 1 74  ? 274.169 258.649 223.574 1.00 54.72  ? 86  GLY   A CA     1 
ATOM   5117 C C      . GLY   F 1 74  ? 273.228 259.262 224.586 1.00 60.13  ? 86  GLY   A C      1 
ATOM   5118 O O      . GLY   F 1 74  ? 273.335 260.465 224.854 1.00 64.30  ? 86  GLY   A O      1 
ATOM   5119 N N      . LYS   F 1 75  ? 272.319 258.482 225.162 1.00 61.19  ? 87  LYS   A N      1 
ATOM   5120 C CA     . LYS   F 1 75  ? 271.355 258.978 226.139 1.00 58.29  ? 87  LYS   A CA     1 
ATOM   5121 C C      . LYS   F 1 75  ? 271.455 258.109 227.383 1.00 57.79  ? 87  LYS   A C      1 
ATOM   5122 O O      . LYS   F 1 75  ? 271.199 256.903 227.318 1.00 63.82  ? 87  LYS   A O      1 
ATOM   5123 C CB     . LYS   F 1 75  ? 269.934 258.944 225.580 1.00 61.93  ? 87  LYS   A CB     1 
ATOM   5124 C CG     . LYS   F 1 75  ? 269.705 259.795 224.350 1.00 61.70  ? 87  LYS   A CG     1 
ATOM   5125 C CD     . LYS   F 1 75  ? 268.312 259.553 223.796 1.00 61.59  ? 87  LYS   A CD     1 
ATOM   5126 C CE     . LYS   F 1 75  ? 268.102 260.279 222.486 1.00 66.38  ? 87  LYS   A CE     1 
ATOM   5127 N NZ     . LYS   F 1 75  ? 269.024 261.438 222.356 1.00 81.09  ? 87  LYS   A NZ     1 
ATOM   5128 N N      . ASP   F 1 76  ? 271.824 258.708 228.509 1.00 53.52  ? 88  ASP   A N      1 
ATOM   5129 C CA     . ASP   F 1 76  ? 271.797 257.963 229.757 1.00 60.95  ? 88  ASP   A CA     1 
ATOM   5130 C C      . ASP   F 1 76  ? 270.353 257.783 230.216 1.00 53.23  ? 88  ASP   A C      1 
ATOM   5131 O O      . ASP   F 1 76  ? 269.534 258.695 230.065 1.00 48.52  ? 88  ASP   A O      1 
ATOM   5132 C CB     . ASP   F 1 76  ? 272.613 258.668 230.838 1.00 62.55  ? 88  ASP   A CB     1 
ATOM   5133 C CG     . ASP   F 1 76  ? 272.193 260.102 231.042 1.00 59.98  ? 88  ASP   A CG     1 
ATOM   5134 O OD1    . ASP   F 1 76  ? 271.802 260.752 230.053 1.00 65.46  ? 88  ASP   A OD1    1 
ATOM   5135 O OD2    . ASP   F 1 76  ? 272.261 260.580 232.192 1.00 57.52  ? 88  ASP   A OD2    1 
ATOM   5136 N N      . PRO   F 1 77  ? 270.007 256.622 230.772 1.00 49.68  ? 89  PRO   A N      1 
ATOM   5137 C CA     . PRO   F 1 77  ? 268.617 256.350 231.149 1.00 52.94  ? 89  PRO   A CA     1 
ATOM   5138 C C      . PRO   F 1 77  ? 268.160 257.021 232.435 1.00 53.03  ? 89  PRO   A C      1 
ATOM   5139 O O      . PRO   F 1 77  ? 267.015 256.811 232.843 1.00 55.42  ? 89  PRO   A O      1 
ATOM   5140 C CB     . PRO   F 1 77  ? 268.609 254.822 231.306 1.00 58.19  ? 89  PRO   A CB     1 
ATOM   5141 C CG     . PRO   F 1 77  ? 269.997 254.482 231.696 1.00 55.76  ? 89  PRO   A CG     1 
ATOM   5142 C CD     . PRO   F 1 77  ? 270.885 255.460 230.992 1.00 50.64  ? 89  PRO   A CD     1 
ATOM   5143 N N      . LYS   F 1 78  ? 269.004 257.820 233.082 1.00 54.28  ? 90  LYS   A N      1 
ATOM   5144 C CA     . LYS   F 1 78  ? 268.639 258.489 234.322 1.00 50.57  ? 90  LYS   A CA     1 
ATOM   5145 C C      . LYS   F 1 78  ? 268.311 259.961 234.130 1.00 49.18  ? 90  LYS   A C      1 
ATOM   5146 O O      . LYS   F 1 78  ? 268.028 260.652 235.113 1.00 48.57  ? 90  LYS   A O      1 
ATOM   5147 C CB     . LYS   F 1 78  ? 269.764 258.340 235.352 1.00 50.93  ? 90  LYS   A CB     1 
ATOM   5148 C CG     . LYS   F 1 78  ? 269.795 256.989 236.040 1.00 49.66  ? 90  LYS   A CG     1 
ATOM   5149 C CD     . LYS   F 1 78  ? 270.057 257.131 237.525 1.00 52.33  ? 90  LYS   A CD     1 
ATOM   5150 C CE     . LYS   F 1 78  ? 270.940 256.008 238.033 1.00 60.47  ? 90  LYS   A CE     1 
ATOM   5151 N NZ     . LYS   F 1 78  ? 270.244 254.695 237.969 1.00 72.05  ? 90  LYS   A NZ     1 
ATOM   5152 N N      . LYS   F 1 79  ? 268.329 260.460 232.897 1.00 51.30  ? 91  LYS   A N      1 
ATOM   5153 C CA     . LYS   F 1 79  ? 268.106 261.871 232.629 1.00 51.30  ? 91  LYS   A CA     1 
ATOM   5154 C C      . LYS   F 1 79  ? 267.036 262.034 231.563 1.00 53.28  ? 91  LYS   A C      1 
ATOM   5155 O O      . LYS   F 1 79  ? 266.993 261.275 230.590 1.00 56.82  ? 91  LYS   A O      1 
ATOM   5156 C CB     . LYS   F 1 79  ? 269.401 262.560 232.190 1.00 49.07  ? 91  LYS   A CB     1 
ATOM   5157 C CG     . LYS   F 1 79  ? 270.074 263.334 233.304 1.00 49.04  ? 91  LYS   A CG     1 
ATOM   5158 C CD     . LYS   F 1 79  ? 271.205 264.194 232.786 1.00 48.11  ? 91  LYS   A CD     1 
ATOM   5159 C CE     . LYS   F 1 79  ? 272.233 264.442 233.871 1.00 48.35  ? 91  LYS   A CE     1 
ATOM   5160 N NZ     . LYS   F 1 79  ? 272.315 265.883 234.225 1.00 57.04  ? 91  LYS   A NZ     1 
ATOM   5161 N N      . THR   F 1 80  ? 266.173 263.026 231.757 1.00 51.91  ? 92  THR   A N      1 
ATOM   5162 C CA     . THR   F 1 80  ? 265.077 263.332 230.852 1.00 49.62  ? 92  THR   A CA     1 
ATOM   5163 C C      . THR   F 1 80  ? 265.119 264.815 230.510 1.00 51.73  ? 92  THR   A C      1 
ATOM   5164 O O      . THR   F 1 80  ? 265.899 265.585 231.077 1.00 57.30  ? 92  THR   A O      1 
ATOM   5165 C CB     . THR   F 1 80  ? 263.723 262.956 231.466 1.00 50.16  ? 92  THR   A CB     1 
ATOM   5166 O OG1    . THR   F 1 80  ? 262.765 262.740 230.424 1.00 53.74  ? 92  THR   A OG1    1 
ATOM   5167 C CG2    . THR   F 1 80  ? 263.229 264.062 232.378 1.00 47.70  ? 92  THR   A CG2    1 
ATOM   5168 N N      . GLY   F 1 81  ? 264.270 265.218 229.572 1.00 51.12  ? 93  GLY   A N      1 
ATOM   5169 C CA     . GLY   F 1 81  ? 264.216 266.613 229.183 1.00 51.84  ? 93  GLY   A CA     1 
ATOM   5170 C C      . GLY   F 1 81  ? 263.415 266.789 227.910 1.00 54.87  ? 93  GLY   A C      1 
ATOM   5171 O O      . GLY   F 1 81  ? 262.685 265.891 227.490 1.00 61.00  ? 93  GLY   A O      1 
ATOM   5172 N N      . GLY   F 1 82  ? 263.569 267.963 227.307 1.00 49.26  ? 94  GLY   A N      1 
ATOM   5173 C CA     . GLY   F 1 82  ? 262.861 268.293 226.097 1.00 47.82  ? 94  GLY   A CA     1 
ATOM   5174 C C      . GLY   F 1 82  ? 263.167 269.694 225.616 1.00 52.09  ? 94  GLY   A C      1 
ATOM   5175 O O      . GLY   F 1 82  ? 263.958 270.426 226.217 1.00 54.11  ? 94  GLY   A O      1 
ATOM   5176 N N      . PRO   F 1 83  ? 262.542 270.093 224.508 1.00 51.65  ? 95  PRO   A N      1 
ATOM   5177 C CA     . PRO   F 1 83  ? 262.793 271.428 223.944 1.00 51.60  ? 95  PRO   A CA     1 
ATOM   5178 C C      . PRO   F 1 83  ? 262.184 272.514 224.818 1.00 52.26  ? 95  PRO   A C      1 
ATOM   5179 O O      . PRO   F 1 83  ? 260.974 272.536 225.050 1.00 55.63  ? 95  PRO   A O      1 
ATOM   5180 C CB     . PRO   F 1 83  ? 262.114 271.365 222.569 1.00 51.62  ? 95  PRO   A CB     1 
ATOM   5181 C CG     . PRO   F 1 83  ? 261.862 269.909 222.314 1.00 51.66  ? 95  PRO   A CG     1 
ATOM   5182 C CD     . PRO   F 1 83  ? 261.652 269.296 223.654 1.00 49.81  ? 95  PRO   A CD     1 
ATOM   5183 N N      . ILE   F 1 84  ? 263.029 273.422 225.295 1.00 51.55  ? 96  ILE   A N      1 
ATOM   5184 C CA     . ILE   F 1 84  ? 262.597 274.588 226.055 1.00 51.60  ? 96  ILE   A CA     1 
ATOM   5185 C C      . ILE   F 1 84  ? 262.861 275.817 225.199 1.00 50.94  ? 96  ILE   A C      1 
ATOM   5186 O O      . ILE   F 1 84  ? 263.998 276.055 224.775 1.00 55.19  ? 96  ILE   A O      1 
ATOM   5187 C CB     . ILE   F 1 84  ? 263.316 274.688 227.407 1.00 51.83  ? 96  ILE   A CB     1 
ATOM   5188 C CG1    . ILE   F 1 84  ? 262.804 273.608 228.357 1.00 49.87  ? 96  ILE   A CG1    1 
ATOM   5189 C CG2    . ILE   F 1 84  ? 263.106 276.061 228.014 1.00 52.12  ? 96  ILE   A CG2    1 
ATOM   5190 C CD1    . ILE   F 1 84  ? 261.320 273.674 228.607 1.00 48.46  ? 96  ILE   A CD1    1 
ATOM   5191 N N      . TYR   F 1 85  ? 261.815 276.593 224.943 1.00 50.09  ? 97  TYR   A N      1 
ATOM   5192 C CA     . TYR   F 1 85  ? 261.889 277.732 224.041 1.00 50.26  ? 97  TYR   A CA     1 
ATOM   5193 C C      . TYR   F 1 85  ? 261.986 279.011 224.862 1.00 51.36  ? 97  TYR   A C      1 
ATOM   5194 O O      . TYR   F 1 85  ? 261.100 279.306 225.671 1.00 53.64  ? 97  TYR   A O      1 
ATOM   5195 C CB     . TYR   F 1 85  ? 260.678 277.759 223.111 1.00 48.83  ? 97  TYR   A CB     1 
ATOM   5196 C CG     . TYR   F 1 85  ? 260.504 276.472 222.337 1.00 50.16  ? 97  TYR   A CG     1 
ATOM   5197 C CD1    . TYR   F 1 85  ? 259.856 275.385 222.903 1.00 51.24  ? 97  TYR   A CD1    1 
ATOM   5198 C CD2    . TYR   F 1 85  ? 261.000 276.337 221.049 1.00 52.54  ? 97  TYR   A CD2    1 
ATOM   5199 C CE1    . TYR   F 1 85  ? 259.699 274.204 222.209 1.00 49.79  ? 97  TYR   A CE1    1 
ATOM   5200 C CE2    . TYR   F 1 85  ? 260.847 275.158 220.346 1.00 53.25  ? 97  TYR   A CE2    1 
ATOM   5201 C CZ     . TYR   F 1 85  ? 260.195 274.095 220.933 1.00 49.00  ? 97  TYR   A CZ     1 
ATOM   5202 O OH     . TYR   F 1 85  ? 260.036 272.918 220.243 1.00 52.55  ? 97  TYR   A OH     1 
ATOM   5203 N N      . ARG   F 1 86  ? 263.062 279.760 224.652 1.00 53.98  ? 98  ARG   A N      1 
ATOM   5204 C CA     . ARG   F 1 86  ? 263.340 280.983 225.385 1.00 54.99  ? 98  ARG   A CA     1 
ATOM   5205 C C      . ARG   F 1 86  ? 263.392 282.154 224.416 1.00 58.13  ? 98  ARG   A C      1 
ATOM   5206 O O      . ARG   F 1 86  ? 264.033 282.074 223.365 1.00 58.35  ? 98  ARG   A O      1 
ATOM   5207 C CB     . ARG   F 1 86  ? 264.662 280.876 226.155 1.00 53.99  ? 98  ARG   A CB     1 
ATOM   5208 C CG     . ARG   F 1 86  ? 264.801 281.869 227.292 1.00 58.43  ? 98  ARG   A CG     1 
ATOM   5209 C CD     . ARG   F 1 86  ? 265.197 281.195 228.598 1.00 57.98  ? 98  ARG   A CD     1 
ATOM   5210 N NE     . ARG   F 1 86  ? 265.973 279.980 228.384 1.00 60.24  ? 98  ARG   A NE     1 
ATOM   5211 C CZ     . ARG   F 1 86  ? 265.960 278.933 229.197 1.00 58.33  ? 98  ARG   A CZ     1 
ATOM   5212 N NH1    . ARG   F 1 86  ? 265.230 278.923 230.299 1.00 55.65  ? 98  ARG   A NH1    1 
ATOM   5213 N NH2    . ARG   F 1 86  ? 266.704 277.872 228.899 1.00 55.15  ? 98  ARG   A NH2    1 
ATOM   5214 N N      . ARG   F 1 87  ? 262.703 283.234 224.769 1.00 60.27  ? 99  ARG   A N      1 
ATOM   5215 C CA     . ARG   F 1 87  ? 262.685 284.452 223.970 1.00 59.00  ? 99  ARG   A CA     1 
ATOM   5216 C C      . ARG   F 1 87  ? 263.581 285.490 224.631 1.00 67.10  ? 99  ARG   A C      1 
ATOM   5217 O O      . ARG   F 1 87  ? 263.238 286.034 225.686 1.00 74.47  ? 99  ARG   A O      1 
ATOM   5218 C CB     . ARG   F 1 87  ? 261.268 284.994 223.825 1.00 58.34  ? 99  ARG   A CB     1 
ATOM   5219 C CG     . ARG   F 1 87  ? 261.192 286.269 223.014 1.00 56.21  ? 99  ARG   A CG     1 
ATOM   5220 C CD     . ARG   F 1 87  ? 259.768 286.589 222.630 1.00 54.99  ? 99  ARG   A CD     1 
ATOM   5221 N NE     . ARG   F 1 87  ? 259.117 287.369 223.675 1.00 60.60  ? 99  ARG   A NE     1 
ATOM   5222 C CZ     . ARG   F 1 87  ? 258.017 288.085 223.498 1.00 66.67  ? 99  ARG   A CZ     1 
ATOM   5223 N NH1    . ARG   F 1 87  ? 257.421 288.156 222.320 1.00 67.71  ? 99  ARG   A NH1    1 
ATOM   5224 N NH2    . ARG   F 1 87  ? 257.501 288.746 224.530 1.00 62.00  ? 99  ARG   A NH2    1 
ATOM   5225 N N      . VAL   F 1 88  ? 264.726 285.764 224.016 1.00 65.67  ? 100 VAL   A N      1 
ATOM   5226 C CA     . VAL   F 1 88  ? 265.584 286.869 224.417 1.00 76.98  ? 100 VAL   A CA     1 
ATOM   5227 C C      . VAL   F 1 88  ? 265.958 287.652 223.167 1.00 73.68  ? 100 VAL   A C      1 
ATOM   5228 O O      . VAL   F 1 88  ? 266.415 287.072 222.176 1.00 69.22  ? 100 VAL   A O      1 
ATOM   5229 C CB     . VAL   F 1 88  ? 266.836 286.381 225.170 1.00 87.09  ? 100 VAL   A CB     1 
ATOM   5230 C CG1    . VAL   F 1 88  ? 267.453 287.521 225.959 1.00 89.05  ? 100 VAL   A CG1    1 
ATOM   5231 C CG2    . VAL   F 1 88  ? 266.482 285.225 226.094 1.00 79.31  ? 100 VAL   A CG2    1 
ATOM   5232 N N      . ASP   F 1 89  ? 265.759 288.967 223.218 1.00 76.14  ? 101 ASP   A N      1 
ATOM   5233 C CA     . ASP   F 1 89  ? 266.054 289.852 222.094 1.00 75.08  ? 101 ASP   A CA     1 
ATOM   5234 C C      . ASP   F 1 89  ? 265.054 289.576 220.965 1.00 74.47  ? 101 ASP   A C      1 
ATOM   5235 O O      . ASP   F 1 89  ? 265.395 289.461 219.792 1.00 76.46  ? 101 ASP   A O      1 
ATOM   5236 C CB     . ASP   F 1 89  ? 267.534 289.699 221.687 1.00 82.06  ? 101 ASP   A CB     1 
ATOM   5237 C CG     . ASP   F 1 89  ? 268.544 290.287 222.685 1.00 99.64  ? 101 ASP   A CG     1 
ATOM   5238 O OD1    . ASP   F 1 89  ? 268.088 291.063 223.548 1.00 110.32 ? 101 ASP   A OD1    1 
ATOM   5239 O OD2    . ASP   F 1 89  ? 269.733 289.932 222.720 1.00 97.80  ? 101 ASP   A OD2    1 
ATOM   5240 N N      . GLY   F 1 90  ? 263.789 289.410 221.341 1.00 71.60  ? 102 GLY   A N      1 
ATOM   5241 C CA     . GLY   F 1 90  ? 262.716 289.342 220.369 1.00 65.19  ? 102 GLY   A CA     1 
ATOM   5242 C C      . GLY   F 1 90  ? 262.566 288.016 219.652 1.00 65.31  ? 102 GLY   A C      1 
ATOM   5243 O O      . GLY   F 1 90  ? 261.458 287.646 219.256 1.00 64.89  ? 102 GLY   A O      1 
ATOM   5244 N N      . LYS   F 1 91  ? 263.668 287.296 219.473 1.00 65.25  ? 103 LYS   A N      1 
ATOM   5245 C CA     . LYS   F 1 91  ? 263.670 286.062 218.704 1.00 60.03  ? 103 LYS   A CA     1 
ATOM   5246 C C      . LYS   F 1 91  ? 263.554 284.845 219.615 1.00 61.92  ? 103 LYS   A C      1 
ATOM   5247 O O      . LYS   F 1 91  ? 263.857 284.896 220.809 1.00 67.43  ? 103 LYS   A O      1 
ATOM   5248 C CB     . LYS   F 1 91  ? 264.936 285.965 217.856 1.00 63.67  ? 103 LYS   A CB     1 
ATOM   5249 C CG     . LYS   F 1 91  ? 264.878 286.792 216.593 1.00 66.59  ? 103 LYS   A CG     1 
ATOM   5250 C CD     . LYS   F 1 91  ? 264.248 286.015 215.460 1.00 69.55  ? 103 LYS   A CD     1 
ATOM   5251 C CE     . LYS   F 1 91  ? 264.129 286.876 214.220 1.00 75.14  ? 103 LYS   A CE     1 
ATOM   5252 N NZ     . LYS   F 1 91  ? 265.098 288.000 214.252 1.00 77.34  ? 103 LYS   A NZ     1 
ATOM   5253 N N      . TRP   F 1 92  ? 263.111 283.739 219.027 1.00 58.90  ? 104 TRP   A N      1 
ATOM   5254 C CA     . TRP   F 1 92  ? 262.931 282.489 219.749 1.00 59.73  ? 104 TRP   A CA     1 
ATOM   5255 C C      . TRP   F 1 92  ? 264.061 281.518 219.433 1.00 60.50  ? 104 TRP   A C      1 
ATOM   5256 O O      . TRP   F 1 92  ? 264.507 281.407 218.289 1.00 65.71  ? 104 TRP   A O      1 
ATOM   5257 C CB     . TRP   F 1 92  ? 261.589 281.850 219.387 1.00 55.93  ? 104 TRP   A CB     1 
ATOM   5258 C CG     . TRP   F 1 92  ? 260.409 282.623 219.871 1.00 53.00  ? 104 TRP   A CG     1 
ATOM   5259 C CD1    . TRP   F 1 92  ? 259.690 283.541 219.168 1.00 52.17  ? 104 TRP   A CD1    1 
ATOM   5260 C CD2    . TRP   F 1 92  ? 259.807 282.549 221.169 1.00 53.33  ? 104 TRP   A CD2    1 
ATOM   5261 N NE1    . TRP   F 1 92  ? 258.680 284.046 219.946 1.00 53.41  ? 104 TRP   A NE1    1 
ATOM   5262 C CE2    . TRP   F 1 92  ? 258.729 283.454 221.179 1.00 52.35  ? 104 TRP   A CE2    1 
ATOM   5263 C CE3    . TRP   F 1 92  ? 260.075 281.809 222.321 1.00 53.66  ? 104 TRP   A CE3    1 
ATOM   5264 C CZ2    . TRP   F 1 92  ? 257.919 283.637 222.294 1.00 52.37  ? 104 TRP   A CZ2    1 
ATOM   5265 C CZ3    . TRP   F 1 92  ? 259.270 281.993 223.428 1.00 52.18  ? 104 TRP   A CZ3    1 
ATOM   5266 C CH2    . TRP   F 1 92  ? 258.207 282.898 223.408 1.00 49.44  ? 104 TRP   A CH2    1 
ATOM   5267 N N      . ARG   F 1 93  ? 264.517 280.807 220.462 1.00 56.63  ? 105 ARG   A N      1 
ATOM   5268 C CA     . ARG   F 1 93  ? 265.498 279.746 220.286 1.00 58.33  ? 105 ARG   A CA     1 
ATOM   5269 C C      . ARG   F 1 93  ? 265.129 278.564 221.167 1.00 57.60  ? 105 ARG   A C      1 
ATOM   5270 O O      . ARG   F 1 93  ? 264.487 278.718 222.207 1.00 58.69  ? 105 ARG   A O      1 
ATOM   5271 C CB     . ARG   F 1 93  ? 266.929 280.206 220.605 1.00 63.06  ? 105 ARG   A CB     1 
ATOM   5272 C CG     . ARG   F 1 93  ? 267.039 281.419 221.499 1.00 68.34  ? 105 ARG   A CG     1 
ATOM   5273 C CD     . ARG   F 1 93  ? 268.400 282.069 221.324 1.00 69.80  ? 105 ARG   A CD     1 
ATOM   5274 N NE     . ARG   F 1 93  ? 268.579 283.227 222.190 1.00 84.24  ? 105 ARG   A NE     1 
ATOM   5275 C CZ     . ARG   F 1 93  ? 267.934 284.375 222.044 1.00 80.02  ? 105 ARG   A CZ     1 
ATOM   5276 N NH1    . ARG   F 1 93  ? 267.037 284.549 221.087 1.00 75.82  ? 105 ARG   A NH1    1 
ATOM   5277 N NH2    . ARG   F 1 93  ? 268.199 285.378 222.874 1.00 75.65  ? 105 ARG   A NH2    1 
ATOM   5278 N N      . ARG   F 1 94  ? 265.544 277.378 220.733 1.00 58.71  ? 106 ARG   A N      1 
ATOM   5279 C CA     . ARG   F 1 94  ? 265.232 276.131 221.414 1.00 55.13  ? 106 ARG   A CA     1 
ATOM   5280 C C      . ARG   F 1 94  ? 266.517 275.480 221.895 1.00 55.23  ? 106 ARG   A C      1 
ATOM   5281 O O      . ARG   F 1 94  ? 267.467 275.325 221.122 1.00 61.01  ? 106 ARG   A O      1 
ATOM   5282 C CB     . ARG   F 1 94  ? 264.475 275.172 220.494 1.00 55.55  ? 106 ARG   A CB     1 
ATOM   5283 C CG     . ARG   F 1 94  ? 264.460 273.737 220.984 1.00 57.86  ? 106 ARG   A CG     1 
ATOM   5284 C CD     . ARG   F 1 94  ? 264.062 272.796 219.870 1.00 54.92  ? 106 ARG   A CD     1 
ATOM   5285 N NE     . ARG   F 1 94  ? 264.516 273.289 218.577 1.00 59.97  ? 106 ARG   A NE     1 
ATOM   5286 C CZ     . ARG   F 1 94  ? 264.058 272.859 217.411 1.00 65.23  ? 106 ARG   A CZ     1 
ATOM   5287 N NH1    . ARG   F 1 94  ? 263.121 271.930 217.338 1.00 66.91  ? 106 ARG   A NH1    1 
ATOM   5288 N NH2    . ARG   F 1 94  ? 264.551 273.376 216.290 1.00 59.49  ? 106 ARG   A NH2    1 
ATOM   5289 N N      . GLU   F 1 95  ? 266.542 275.103 223.169 1.00 53.04  ? 107 GLU   A N      1 
ATOM   5290 C CA     . GLU   F 1 95  ? 267.675 274.408 223.759 1.00 54.72  ? 107 GLU   A CA     1 
ATOM   5291 C C      . GLU   F 1 95  ? 267.162 273.205 224.531 1.00 54.81  ? 107 GLU   A C      1 
ATOM   5292 O O      . GLU   F 1 95  ? 266.191 273.317 225.285 1.00 54.93  ? 107 GLU   A O      1 
ATOM   5293 C CB     . GLU   F 1 95  ? 268.486 275.343 224.665 1.00 53.22  ? 107 GLU   A CB     1 
ATOM   5294 C CG     . GLU   F 1 95  ? 267.714 275.933 225.832 1.00 53.28  ? 107 GLU   A CG     1 
ATOM   5295 C CD     . GLU   F 1 95  ? 267.735 275.050 227.059 1.00 65.14  ? 107 GLU   A CD     1 
ATOM   5296 O OE1    . GLU   F 1 95  ? 268.473 274.043 227.058 1.00 66.69  ? 107 GLU   A OE1    1 
ATOM   5297 O OE2    . GLU   F 1 95  ? 267.017 275.367 228.030 1.00 69.71  ? 107 GLU   A OE2    1 
ATOM   5298 N N      . LEU   F 1 96  ? 267.803 272.058 224.332 1.00 54.55  ? 108 LEU   A N      1 
ATOM   5299 C CA     . LEU   F 1 96  ? 267.404 270.844 225.024 1.00 53.01  ? 108 LEU   A CA     1 
ATOM   5300 C C      . LEU   F 1 96  ? 267.847 270.908 226.478 1.00 54.14  ? 108 LEU   A C      1 
ATOM   5301 O O      . LEU   F 1 96  ? 269.023 271.142 226.771 1.00 51.39  ? 108 LEU   A O      1 
ATOM   5302 C CB     . LEU   F 1 96  ? 268.000 269.612 224.344 1.00 48.10  ? 108 LEU   A CB     1 
ATOM   5303 C CG     . LEU   F 1 96  ? 267.011 268.682 223.639 1.00 47.11  ? 108 LEU   A CG     1 
ATOM   5304 C CD1    . LEU   F 1 96  ? 266.415 269.363 222.420 1.00 53.55  ? 108 LEU   A CD1    1 
ATOM   5305 C CD2    . LEU   F 1 96  ? 267.671 267.369 223.259 1.00 40.37  ? 108 LEU   A CD2    1 
ATOM   5306 N N      . ILE   F 1 97  ? 266.906 270.702 227.384 1.00 54.04  ? 109 ILE   A N      1 
ATOM   5307 C CA     . ILE   F 1 97  ? 267.181 270.658 228.812 1.00 52.19  ? 109 ILE   A CA     1 
ATOM   5308 C C      . ILE   F 1 97  ? 267.242 269.206 229.252 1.00 54.50  ? 109 ILE   A C      1 
ATOM   5309 O O      . ILE   F 1 97  ? 266.357 268.406 228.924 1.00 57.44  ? 109 ILE   A O      1 
ATOM   5310 C CB     . ILE   F 1 97  ? 266.118 271.436 229.609 1.00 52.50  ? 109 ILE   A CB     1 
ATOM   5311 C CG1    . ILE   F 1 97  ? 266.397 272.936 229.546 1.00 50.83  ? 109 ILE   A CG1    1 
ATOM   5312 C CG2    . ILE   F 1 97  ? 266.080 270.962 231.046 1.00 57.91  ? 109 ILE   A CG2    1 
ATOM   5313 C CD1    . ILE   F 1 97  ? 267.829 273.294 229.860 1.00 46.81  ? 109 ILE   A CD1    1 
ATOM   5314 N N      . LEU   F 1 98  ? 268.291 268.862 229.991 1.00 53.10  ? 110 LEU   A N      1 
ATOM   5315 C CA     . LEU   F 1 98  ? 268.465 267.530 230.548 1.00 51.57  ? 110 LEU   A CA     1 
ATOM   5316 C C      . LEU   F 1 98  ? 268.287 267.612 232.054 1.00 51.74  ? 110 LEU   A C      1 
ATOM   5317 O O      . LEU   F 1 98  ? 268.863 268.490 232.704 1.00 49.61  ? 110 LEU   A O      1 
ATOM   5318 C CB     . LEU   F 1 98  ? 269.840 266.955 230.203 1.00 50.37  ? 110 LEU   A CB     1 
ATOM   5319 C CG     . LEU   F 1 98  ? 270.180 266.847 228.719 1.00 53.71  ? 110 LEU   A CG     1 
ATOM   5320 C CD1    . LEU   F 1 98  ? 271.158 265.712 228.476 1.00 56.24  ? 110 LEU   A CD1    1 
ATOM   5321 C CD2    . LEU   F 1 98  ? 268.918 266.644 227.905 1.00 52.70  ? 110 LEU   A CD2    1 
ATOM   5322 N N      . TYR   F 1 99  ? 267.489 266.702 232.602 1.00 50.95  ? 111 TYR   A N      1 
ATOM   5323 C CA     . TYR   F 1 99  ? 267.164 266.722 234.017 1.00 47.94  ? 111 TYR   A CA     1 
ATOM   5324 C C      . TYR   F 1 99  ? 267.147 265.305 234.559 1.00 47.96  ? 111 TYR   A C      1 
ATOM   5325 O O      . TYR   F 1 99  ? 266.717 264.376 233.871 1.00 52.37  ? 111 TYR   A O      1 
ATOM   5326 C CB     . TYR   F 1 99  ? 265.807 267.383 234.262 1.00 52.68  ? 111 TYR   A CB     1 
ATOM   5327 C CG     . TYR   F 1 99  ? 265.921 268.771 234.827 1.00 48.83  ? 111 TYR   A CG     1 
ATOM   5328 C CD1    . TYR   F 1 99  ? 266.122 268.967 236.179 1.00 49.81  ? 111 TYR   A CD1    1 
ATOM   5329 C CD2    . TYR   F 1 99  ? 265.830 269.884 234.008 1.00 51.02  ? 111 TYR   A CD2    1 
ATOM   5330 C CE1    . TYR   F 1 99  ? 266.235 270.229 236.700 1.00 56.24  ? 111 TYR   A CE1    1 
ATOM   5331 C CE2    . TYR   F 1 99  ? 265.937 271.156 234.521 1.00 49.38  ? 111 TYR   A CE2    1 
ATOM   5332 C CZ     . TYR   F 1 99  ? 266.137 271.320 235.865 1.00 56.02  ? 111 TYR   A CZ     1 
ATOM   5333 O OH     . TYR   F 1 99  ? 266.244 272.589 236.388 1.00 64.22  ? 111 TYR   A OH     1 
ATOM   5334 N N      . ASP   F 1 100 ? 267.612 265.145 235.794 1.00 49.95  ? 112 ASP   A N      1 
ATOM   5335 C CA     . ASP   F 1 100 ? 267.496 263.856 236.455 1.00 50.75  ? 112 ASP   A CA     1 
ATOM   5336 C C      . ASP   F 1 100 ? 266.030 263.521 236.679 1.00 50.46  ? 112 ASP   A C      1 
ATOM   5337 O O      . ASP   F 1 100 ? 265.242 264.361 237.121 1.00 51.40  ? 112 ASP   A O      1 
ATOM   5338 C CB     . ASP   F 1 100 ? 268.236 263.855 237.792 1.00 51.82  ? 112 ASP   A CB     1 
ATOM   5339 C CG     . ASP   F 1 100 ? 269.541 264.605 237.737 1.00 61.36  ? 112 ASP   A CG     1 
ATOM   5340 O OD1    . ASP   F 1 100 ? 270.599 263.972 237.942 1.00 67.02  ? 112 ASP   A OD1    1 
ATOM   5341 O OD2    . ASP   F 1 100 ? 269.507 265.829 237.496 1.00 64.57  ? 112 ASP   A OD2    1 
ATOM   5342 N N      . LYS   F 1 101 ? 265.665 262.280 236.369 1.00 49.15  ? 113 LYS   A N      1 
ATOM   5343 C CA     . LYS   F 1 101 ? 264.291 261.852 236.588 1.00 47.64  ? 113 LYS   A CA     1 
ATOM   5344 C C      . LYS   F 1 101 ? 263.961 261.823 238.074 1.00 47.32  ? 113 LYS   A C      1 
ATOM   5345 O O      . LYS   F 1 101 ? 262.803 262.012 238.463 1.00 49.84  ? 113 LYS   A O      1 
ATOM   5346 C CB     . LYS   F 1 101 ? 264.066 260.489 235.936 1.00 45.68  ? 113 LYS   A CB     1 
ATOM   5347 C CG     . LYS   F 1 101 ? 264.445 260.483 234.464 1.00 46.65  ? 113 LYS   A CG     1 
ATOM   5348 C CD     . LYS   F 1 101 ? 264.550 259.085 233.890 1.00 47.00  ? 113 LYS   A CD     1 
ATOM   5349 C CE     . LYS   F 1 101 ? 263.508 258.862 232.814 1.00 42.32  ? 113 LYS   A CE     1 
ATOM   5350 N NZ     . LYS   F 1 101 ? 264.013 257.993 231.723 1.00 37.92  ? 113 LYS   A NZ     1 
ATOM   5351 N N      . GLU   F 1 102 ? 264.966 261.586 238.921 1.00 48.06  ? 114 GLU   A N      1 
ATOM   5352 C CA     . GLU   F 1 102 ? 264.734 261.590 240.361 1.00 50.81  ? 114 GLU   A CA     1 
ATOM   5353 C C      . GLU   F 1 102 ? 264.536 263.007 240.884 1.00 50.10  ? 114 GLU   A C      1 
ATOM   5354 O O      . GLU   F 1 102 ? 263.728 263.235 241.792 1.00 53.15  ? 114 GLU   A O      1 
ATOM   5355 C CB     . GLU   F 1 102 ? 265.891 260.900 241.080 1.00 49.28  ? 114 GLU   A CB     1 
ATOM   5356 C CG     . GLU   F 1 102 ? 265.877 261.070 242.585 1.00 54.52  ? 114 GLU   A CG     1 
ATOM   5357 C CD     . GLU   F 1 102 ? 267.209 260.734 243.217 1.00 72.42  ? 114 GLU   A CD     1 
ATOM   5358 O OE1    . GLU   F 1 102 ? 268.253 261.105 242.639 1.00 76.40  ? 114 GLU   A OE1    1 
ATOM   5359 O OE2    . GLU   F 1 102 ? 267.214 260.097 244.291 1.00 84.04  ? 114 GLU   A OE2    1 
ATOM   5360 N N      . GLU   F 1 103 ? 265.269 263.974 240.329 1.00 47.86  ? 115 GLU   A N      1 
ATOM   5361 C CA     . GLU   F 1 103 ? 265.067 265.365 240.721 1.00 49.13  ? 115 GLU   A CA     1 
ATOM   5362 C C      . GLU   F 1 103 ? 263.683 265.851 240.316 1.00 50.59  ? 115 GLU   A C      1 
ATOM   5363 O O      . GLU   F 1 103 ? 263.010 266.548 241.084 1.00 51.03  ? 115 GLU   A O      1 
ATOM   5364 C CB     . GLU   F 1 103 ? 266.150 266.246 240.102 1.00 51.75  ? 115 GLU   A CB     1 
ATOM   5365 C CG     . GLU   F 1 103 ? 265.985 267.727 240.389 1.00 54.45  ? 115 GLU   A CG     1 
ATOM   5366 C CD     . GLU   F 1 103 ? 266.519 268.120 241.748 1.00 57.65  ? 115 GLU   A CD     1 
ATOM   5367 O OE1    . GLU   F 1 103 ? 267.182 267.282 242.392 1.00 63.82  ? 115 GLU   A OE1    1 
ATOM   5368 O OE2    . GLU   F 1 103 ? 266.280 269.269 242.172 1.00 54.18  ? 115 GLU   A OE2    1 
ATOM   5369 N N      . ILE   F 1 104 ? 263.238 265.490 239.112 1.00 49.35  ? 116 ILE   A N      1 
ATOM   5370 C CA     . ILE   F 1 104 ? 261.882 265.823 238.691 1.00 46.84  ? 116 ILE   A CA     1 
ATOM   5371 C C      . ILE   F 1 104 ? 260.869 265.178 239.626 1.00 46.72  ? 116 ILE   A C      1 
ATOM   5372 O O      . ILE   F 1 104 ? 259.874 265.802 240.014 1.00 48.30  ? 116 ILE   A O      1 
ATOM   5373 C CB     . ILE   F 1 104 ? 261.654 265.395 237.230 1.00 48.91  ? 116 ILE   A CB     1 
ATOM   5374 C CG1    . ILE   F 1 104 ? 262.537 266.213 236.290 1.00 48.44  ? 116 ILE   A CG1    1 
ATOM   5375 C CG2    . ILE   F 1 104 ? 260.193 265.545 236.856 1.00 52.51  ? 116 ILE   A CG2    1 
ATOM   5376 C CD1    . ILE   F 1 104 ? 262.142 267.662 236.201 1.00 51.86  ? 116 ILE   A CD1    1 
ATOM   5377 N N      . ARG   F 1 105 ? 261.106 263.919 240.000 1.00 47.70  ? 117 ARG   A N      1 
ATOM   5378 C CA     . ARG   F 1 105 ? 260.186 263.221 240.891 1.00 46.51  ? 117 ARG   A CA     1 
ATOM   5379 C C      . ARG   F 1 105 ? 260.083 263.923 242.239 1.00 45.74  ? 117 ARG   A C      1 
ATOM   5380 O O      . ARG   F 1 105 ? 258.984 264.077 242.785 1.00 45.65  ? 117 ARG   A O      1 
ATOM   5381 C CB     . ARG   F 1 105 ? 260.639 261.773 241.075 1.00 43.58  ? 117 ARG   A CB     1 
ATOM   5382 C CG     . ARG   F 1 105 ? 260.388 260.888 239.870 1.00 43.39  ? 117 ARG   A CG     1 
ATOM   5383 C CD     . ARG   F 1 105 ? 260.430 259.419 240.242 1.00 46.51  ? 117 ARG   A CD     1 
ATOM   5384 N NE     . ARG   F 1 105 ? 261.742 259.006 240.725 1.00 52.92  ? 117 ARG   A NE     1 
ATOM   5385 C CZ     . ARG   F 1 105 ? 262.716 258.554 239.948 1.00 54.25  ? 117 ARG   A CZ     1 
ATOM   5386 N NH1    . ARG   F 1 105 ? 262.565 258.456 238.638 1.00 52.08  ? 117 ARG   A NH1    1 
ATOM   5387 N NH2    . ARG   F 1 105 ? 263.870 258.191 240.498 1.00 55.18  ? 117 ARG   A NH2    1 
ATOM   5388 N N      . ARG   F 1 106 ? 261.217 264.351 242.795 1.00 46.24  ? 118 ARG   A N      1 
ATOM   5389 C CA     . ARG   F 1 106 ? 261.193 265.019 244.092 1.00 44.93  ? 118 ARG   A CA     1 
ATOM   5390 C C      . ARG   F 1 106 ? 260.428 266.335 244.018 1.00 44.51  ? 118 ARG   A C      1 
ATOM   5391 O O      . ARG   F 1 106 ? 259.672 266.676 244.934 1.00 42.38  ? 118 ARG   A O      1 
ATOM   5392 C CB     . ARG   F 1 106 ? 262.619 265.259 244.585 1.00 43.26  ? 118 ARG   A CB     1 
ATOM   5393 C CG     . ARG   F 1 106 ? 262.692 266.067 245.864 1.00 44.90  ? 118 ARG   A CG     1 
ATOM   5394 C CD     . ARG   F 1 106 ? 264.081 266.625 246.091 1.00 48.84  ? 118 ARG   A CD     1 
ATOM   5395 N NE     . ARG   F 1 106 ? 264.348 267.776 245.239 1.00 53.24  ? 118 ARG   A NE     1 
ATOM   5396 C CZ     . ARG   F 1 106 ? 263.854 268.988 245.448 1.00 47.96  ? 118 ARG   A CZ     1 
ATOM   5397 N NH1    . ARG   F 1 106 ? 263.054 269.241 246.469 1.00 47.80  ? 118 ARG   A NH1    1 
ATOM   5398 N NH2    . ARG   F 1 106 ? 264.171 269.972 244.612 1.00 44.20  ? 118 ARG   A NH2    1 
ATOM   5399 N N      . ILE   F 1 107 ? 260.621 267.091 242.936 1.00 47.48  ? 119 ILE   A N      1 
ATOM   5400 C CA     . ILE   F 1 107 ? 259.915 268.358 242.774 1.00 45.74  ? 119 ILE   A CA     1 
ATOM   5401 C C      . ILE   F 1 107 ? 258.414 268.125 242.680 1.00 45.56  ? 119 ILE   A C      1 
ATOM   5402 O O      . ILE   F 1 107 ? 257.617 268.852 243.285 1.00 44.99  ? 119 ILE   A O      1 
ATOM   5403 C CB     . ILE   F 1 107 ? 260.448 269.110 241.542 1.00 45.62  ? 119 ILE   A CB     1 
ATOM   5404 C CG1    . ILE   F 1 107 ? 261.897 269.537 241.765 1.00 47.61  ? 119 ILE   A CG1    1 
ATOM   5405 C CG2    . ILE   F 1 107 ? 259.581 270.317 241.240 1.00 49.23  ? 119 ILE   A CG2    1 
ATOM   5406 C CD1    . ILE   F 1 107 ? 262.520 270.204 240.567 1.00 52.21  ? 119 ILE   A CD1    1 
ATOM   5407 N N      . TRP   F 1 108 ? 258.003 267.118 241.907 1.00 45.51  ? 120 TRP   A N      1 
ATOM   5408 C CA     . TRP   F 1 108 ? 256.585 266.799 241.794 1.00 46.06  ? 120 TRP   A CA     1 
ATOM   5409 C C      . TRP   F 1 108 ? 256.016 266.337 243.128 1.00 46.08  ? 120 TRP   A C      1 
ATOM   5410 O O      . TRP   F 1 108 ? 254.945 266.789 243.547 1.00 44.83  ? 120 TRP   A O      1 
ATOM   5411 C CB     . TRP   F 1 108 ? 256.380 265.731 240.720 1.00 43.55  ? 120 TRP   A CB     1 
ATOM   5412 C CG     . TRP   F 1 108 ? 255.011 265.127 240.696 1.00 43.92  ? 120 TRP   A CG     1 
ATOM   5413 C CD1    . TRP   F 1 108 ? 254.630 263.943 241.248 1.00 45.95  ? 120 TRP   A CD1    1 
ATOM   5414 C CD2    . TRP   F 1 108 ? 253.843 265.671 240.070 1.00 45.05  ? 120 TRP   A CD2    1 
ATOM   5415 N NE1    . TRP   F 1 108 ? 253.297 263.717 241.014 1.00 45.53  ? 120 TRP   A NE1    1 
ATOM   5416 C CE2    . TRP   F 1 108 ? 252.792 264.763 240.290 1.00 45.52  ? 120 TRP   A CE2    1 
ATOM   5417 C CE3    . TRP   F 1 108 ? 253.584 266.839 239.348 1.00 46.96  ? 120 TRP   A CE3    1 
ATOM   5418 C CZ2    . TRP   F 1 108 ? 251.503 264.988 239.818 1.00 47.34  ? 120 TRP   A CZ2    1 
ATOM   5419 C CZ3    . TRP   F 1 108 ? 252.305 267.058 238.879 1.00 44.75  ? 120 TRP   A CZ3    1 
ATOM   5420 C CH2    . TRP   F 1 108 ? 251.281 266.138 239.115 1.00 43.88  ? 120 TRP   A CH2    1 
ATOM   5421 N N      . ARG   F 1 109 ? 256.727 265.443 243.817 1.00 47.72  ? 121 ARG   A N      1 
ATOM   5422 C CA     . ARG   F 1 109 ? 256.232 264.929 245.088 1.00 47.71  ? 121 ARG   A CA     1 
ATOM   5423 C C      . ARG   F 1 109 ? 256.139 266.031 246.133 1.00 46.31  ? 121 ARG   A C      1 
ATOM   5424 O O      . ARG   F 1 109 ? 255.177 266.079 246.909 1.00 49.99  ? 121 ARG   A O      1 
ATOM   5425 C CB     . ARG   F 1 109 ? 257.126 263.792 245.578 1.00 46.20  ? 121 ARG   A CB     1 
ATOM   5426 C CG     . ARG   F 1 109 ? 256.768 262.434 245.005 1.00 46.66  ? 121 ARG   A CG     1 
ATOM   5427 C CD     . ARG   F 1 109 ? 257.785 261.383 245.404 1.00 44.50  ? 121 ARG   A CD     1 
ATOM   5428 N NE     . ARG   F 1 109 ? 257.613 260.141 244.661 1.00 43.41  ? 121 ARG   A NE     1 
ATOM   5429 C CZ     . ARG   F 1 109 ? 258.611 259.399 244.202 1.00 44.95  ? 121 ARG   A CZ     1 
ATOM   5430 N NH1    . ARG   F 1 109 ? 259.872 259.758 244.370 1.00 42.46  ? 121 ARG   A NH1    1 
ATOM   5431 N NH2    . ARG   F 1 109 ? 258.336 258.266 243.565 1.00 50.18  ? 121 ARG   A NH2    1 
ATOM   5432 N N      . GLN   F 1 110 ? 257.129 266.922 246.175 1.00 44.86  ? 122 GLN   A N      1 
ATOM   5433 C CA     . GLN   F 1 110 ? 257.098 268.005 247.151 1.00 46.43  ? 122 GLN   A CA     1 
ATOM   5434 C C      . GLN   F 1 110 ? 255.932 268.947 246.885 1.00 47.41  ? 122 GLN   A C      1 
ATOM   5435 O O      . GLN   F 1 110 ? 255.309 269.456 247.823 1.00 47.68  ? 122 GLN   A O      1 
ATOM   5436 C CB     . GLN   F 1 110 ? 258.426 268.760 247.136 1.00 46.59  ? 122 GLN   A CB     1 
ATOM   5437 C CG     . GLN   F 1 110 ? 258.303 270.243 247.396 1.00 51.66  ? 122 GLN   A CG     1 
ATOM   5438 C CD     . GLN   F 1 110 ? 259.643 270.893 247.656 1.00 58.51  ? 122 GLN   A CD     1 
ATOM   5439 O OE1    . GLN   F 1 110 ? 260.662 270.477 247.109 1.00 62.37  ? 122 GLN   A OE1    1 
ATOM   5440 N NE2    . GLN   F 1 110 ? 259.651 271.914 248.501 1.00 66.70  ? 122 GLN   A NE2    1 
ATOM   5441 N N      . ALA   F 1 111 ? 255.623 269.189 245.610 1.00 47.07  ? 123 ALA   A N      1 
ATOM   5442 C CA     . ALA   F 1 111 ? 254.485 270.030 245.258 1.00 45.29  ? 123 ALA   A CA     1 
ATOM   5443 C C      . ALA   F 1 111 ? 253.151 269.404 245.648 1.00 44.64  ? 123 ALA   A C      1 
ATOM   5444 O O      . ALA   F 1 111 ? 252.156 270.124 245.769 1.00 41.56  ? 123 ALA   A O      1 
ATOM   5445 C CB     . ALA   F 1 111 ? 254.502 270.332 243.761 1.00 46.81  ? 123 ALA   A CB     1 
ATOM   5446 N N      . ASN   F 1 112 ? 253.107 268.087 245.847 1.00 46.25  ? 124 ASN   A N      1 
ATOM   5447 C CA     . ASN   F 1 112 ? 251.900 267.393 246.279 1.00 46.52  ? 124 ASN   A CA     1 
ATOM   5448 C C      . ASN   F 1 112 ? 251.974 266.978 247.744 1.00 49.66  ? 124 ASN   A C      1 
ATOM   5449 O O      . ASN   F 1 112 ? 251.359 265.989 248.148 1.00 52.33  ? 124 ASN   A O      1 
ATOM   5450 C CB     . ASN   F 1 112 ? 251.635 266.176 245.396 1.00 46.52  ? 124 ASN   A CB     1 
ATOM   5451 C CG     . ASN   F 1 112 ? 251.580 266.525 243.927 1.00 50.17  ? 124 ASN   A CG     1 
ATOM   5452 O OD1    . ASN   F 1 112 ? 251.211 267.636 243.554 1.00 55.34  ? 124 ASN   A OD1    1 
ATOM   5453 N ND2    . ASN   F 1 112 ? 251.955 265.577 243.082 1.00 52.15  ? 124 ASN   A ND2    1 
ATOM   5454 N N      . ASN   F 1 113 ? 252.718 267.731 248.552 1.00 52.51  ? 125 ASN   A N      1 
ATOM   5455 C CA     . ASN   F 1 113 ? 252.856 267.449 249.979 1.00 50.07  ? 125 ASN   A CA     1 
ATOM   5456 C C      . ASN   F 1 113 ? 253.431 266.055 250.221 1.00 50.92  ? 125 ASN   A C      1 
ATOM   5457 O O      . ASN   F 1 113 ? 252.996 265.330 251.117 1.00 51.96  ? 125 ASN   A O      1 
ATOM   5458 C CB     . ASN   F 1 113 ? 251.519 267.621 250.701 1.00 54.21  ? 125 ASN   A CB     1 
ATOM   5459 C CG     . ASN   F 1 113 ? 251.045 269.059 250.710 1.00 54.74  ? 125 ASN   A CG     1 
ATOM   5460 O OD1    . ASN   F 1 113 ? 251.175 269.772 249.717 1.00 48.17  ? 125 ASN   A OD1    1 
ATOM   5461 N ND2    . ASN   F 1 113 ? 250.495 269.494 251.836 1.00 61.10  ? 125 ASN   A ND2    1 
ATOM   5462 N N      . GLY   F 1 114 ? 254.418 265.678 249.414 1.00 51.52  ? 126 GLY   A N      1 
ATOM   5463 C CA     . GLY   F 1 114 ? 255.138 264.438 249.614 1.00 51.09  ? 126 GLY   A CA     1 
ATOM   5464 C C      . GLY   F 1 114 ? 254.430 263.190 249.144 1.00 53.70  ? 126 GLY   A C      1 
ATOM   5465 O O      . GLY   F 1 114 ? 254.960 262.090 249.333 1.00 61.48  ? 126 GLY   A O      1 
ATOM   5466 N N      . ASP   F 1 115 ? 253.259 263.319 248.535 1.00 51.52  ? 127 ASP   A N      1 
ATOM   5467 C CA     . ASP   F 1 115 ? 252.491 262.178 248.068 1.00 52.92  ? 127 ASP   A CA     1 
ATOM   5468 C C      . ASP   F 1 115 ? 252.739 261.970 246.579 1.00 53.87  ? 127 ASP   A C      1 
ATOM   5469 O O      . ASP   F 1 115 ? 253.021 262.916 245.841 1.00 54.13  ? 127 ASP   A O      1 
ATOM   5470 C CB     . ASP   F 1 115 ? 250.999 262.390 248.349 1.00 51.57  ? 127 ASP   A CB     1 
ATOM   5471 C CG     . ASP   F 1 115 ? 250.104 261.548 247.465 1.00 60.62  ? 127 ASP   A CG     1 
ATOM   5472 O OD1    . ASP   F 1 115 ? 250.520 260.442 247.061 1.00 66.28  ? 127 ASP   A OD1    1 
ATOM   5473 O OD2    . ASP   F 1 115 ? 248.977 261.996 247.173 1.00 63.07  ? 127 ASP   A OD2    1 
ATOM   5474 N N      . ASP   F 1 116 ? 252.637 260.713 246.143 1.00 54.36  ? 128 ASP   A N      1 
ATOM   5475 C CA     . ASP   F 1 116 ? 252.891 260.398 244.741 1.00 49.59  ? 128 ASP   A CA     1 
ATOM   5476 C C      . ASP   F 1 116 ? 251.952 261.176 243.830 1.00 51.30  ? 128 ASP   A C      1 
ATOM   5477 O O      . ASP   F 1 116 ? 252.374 261.728 242.808 1.00 56.12  ? 128 ASP   A O      1 
ATOM   5478 C CB     . ASP   F 1 116 ? 252.744 258.895 244.502 1.00 48.68  ? 128 ASP   A CB     1 
ATOM   5479 C CG     . ASP   F 1 116 ? 253.867 258.093 245.119 1.00 60.23  ? 128 ASP   A CG     1 
ATOM   5480 O OD1    . ASP   F 1 116 ? 254.898 258.692 245.483 1.00 65.69  ? 128 ASP   A OD1    1 
ATOM   5481 O OD2    . ASP   F 1 116 ? 253.723 256.858 245.228 1.00 65.27  ? 128 ASP   A OD2    1 
ATOM   5482 N N      . ALA   F 1 117 ? 250.674 261.238 244.190 1.00 49.83  ? 129 ALA   A N      1 
ATOM   5483 C CA     . ALA   F 1 117 ? 249.667 261.948 243.408 1.00 45.52  ? 129 ALA   A CA     1 
ATOM   5484 C C      . ALA   F 1 117 ? 249.676 261.478 241.956 1.00 46.57  ? 129 ALA   A C      1 
ATOM   5485 O O      . ALA   F 1 117 ? 249.980 262.225 241.025 1.00 48.00  ? 129 ALA   A O      1 
ATOM   5486 C CB     . ALA   F 1 117 ? 249.868 263.461 243.499 1.00 49.69  ? 129 ALA   A CB     1 
ATOM   5487 N N      . THR   F 1 118 ? 249.340 260.201 241.778 1.00 46.99  ? 130 THR   A N      1 
ATOM   5488 C CA     . THR   F 1 118 ? 249.240 259.635 240.440 1.00 47.38  ? 130 THR   A CA     1 
ATOM   5489 C C      . THR   F 1 118 ? 248.061 260.193 239.654 1.00 45.38  ? 130 THR   A C      1 
ATOM   5490 O O      . THR   F 1 118 ? 248.018 260.021 238.432 1.00 44.58  ? 130 THR   A O      1 
ATOM   5491 C CB     . THR   F 1 118 ? 249.142 258.113 240.530 1.00 46.54  ? 130 THR   A CB     1 
ATOM   5492 O OG1    . THR   F 1 118 ? 250.291 257.604 241.216 1.00 43.27  ? 130 THR   A OG1    1 
ATOM   5493 C CG2    . THR   F 1 118 ? 249.077 257.502 239.149 1.00 52.71  ? 130 THR   A CG2    1 
ATOM   5494 N N      . ALA   F 1 119 ? 247.112 260.854 240.319 1.00 44.19  ? 131 ALA   A N      1 
ATOM   5495 C CA     . ALA   F 1 119 ? 245.996 261.463 239.605 1.00 42.08  ? 131 ALA   A CA     1 
ATOM   5496 C C      . ALA   F 1 119 ? 246.469 262.601 238.711 1.00 43.58  ? 131 ALA   A C      1 
ATOM   5497 O O      . ALA   F 1 119 ? 246.000 262.745 237.576 1.00 44.56  ? 131 ALA   A O      1 
ATOM   5498 C CB     . ALA   F 1 119 ? 244.948 261.960 240.599 1.00 43.57  ? 131 ALA   A CB     1 
ATOM   5499 N N      . GLY   F 1 120 ? 247.396 263.422 239.204 1.00 41.59  ? 132 GLY   A N      1 
ATOM   5500 C CA     . GLY   F 1 120 ? 247.892 264.524 238.398 1.00 39.59  ? 132 GLY   A CA     1 
ATOM   5501 C C      . GLY   F 1 120 ? 248.585 264.054 237.134 1.00 43.56  ? 132 GLY   A C      1 
ATOM   5502 O O      . GLY   F 1 120 ? 248.402 264.634 236.061 1.00 41.71  ? 132 GLY   A O      1 
ATOM   5503 N N      . LEU   F 1 121 ? 249.389 262.995 237.243 1.00 47.98  ? 133 LEU   A N      1 
ATOM   5504 C CA     . LEU   F 1 121 ? 250.079 262.466 236.072 1.00 46.98  ? 133 LEU   A CA     1 
ATOM   5505 C C      . LEU   F 1 121 ? 249.089 261.951 235.035 1.00 46.21  ? 133 LEU   A C      1 
ATOM   5506 O O      . LEU   F 1 121 ? 249.246 262.207 233.836 1.00 44.45  ? 133 LEU   A O      1 
ATOM   5507 C CB     . LEU   F 1 121 ? 251.045 261.359 236.492 1.00 49.33  ? 133 LEU   A CB     1 
ATOM   5508 C CG     . LEU   F 1 121 ? 252.115 261.754 237.510 1.00 44.52  ? 133 LEU   A CG     1 
ATOM   5509 C CD1    . LEU   F 1 121 ? 252.979 260.561 237.870 1.00 45.41  ? 133 LEU   A CD1    1 
ATOM   5510 C CD2    . LEU   F 1 121 ? 252.967 262.887 236.973 1.00 46.74  ? 133 LEU   A CD2    1 
ATOM   5511 N N      . THR   F 1 122 ? 248.061 261.224 235.477 1.00 46.74  ? 134 THR   A N      1 
ATOM   5512 C CA     . THR   F 1 122 ? 247.055 260.731 234.544 1.00 44.34  ? 134 THR   A CA     1 
ATOM   5513 C C      . THR   F 1 122 ? 246.269 261.876 233.920 1.00 43.72  ? 134 THR   A C      1 
ATOM   5514 O O      . THR   F 1 122 ? 245.901 261.804 232.743 1.00 44.60  ? 134 THR   A O      1 
ATOM   5515 C CB     . THR   F 1 122 ? 246.107 259.763 235.253 1.00 43.03  ? 134 THR   A CB     1 
ATOM   5516 O OG1    . THR   F 1 122 ? 246.869 258.805 235.994 1.00 44.26  ? 134 THR   A OG1    1 
ATOM   5517 C CG2    . THR   F 1 122 ? 245.240 259.033 234.245 1.00 49.12  ? 134 THR   A CG2    1 
ATOM   5518 N N      . HIS   F 1 123 ? 246.013 262.936 234.686 1.00 43.49  ? 135 HIS   A N      1 
ATOM   5519 C CA     . HIS   F 1 123 ? 245.318 264.098 234.146 1.00 41.94  ? 135 HIS   A CA     1 
ATOM   5520 C C      . HIS   F 1 123 ? 246.107 264.719 233.000 1.00 42.71  ? 135 HIS   A C      1 
ATOM   5521 O O      . HIS   F 1 123 ? 245.542 265.083 231.964 1.00 43.59  ? 135 HIS   A O      1 
ATOM   5522 C CB     . HIS   F 1 123 ? 245.079 265.114 235.263 1.00 39.19  ? 135 HIS   A CB     1 
ATOM   5523 C CG     . HIS   F 1 123 ? 244.273 266.302 234.845 1.00 42.93  ? 135 HIS   A CG     1 
ATOM   5524 N ND1    . HIS   F 1 123 ? 242.900 266.268 234.740 1.00 44.45  ? 135 HIS   A ND1    1 
ATOM   5525 C CD2    . HIS   F 1 123 ? 244.645 267.562 234.521 1.00 45.48  ? 135 HIS   A CD2    1 
ATOM   5526 C CE1    . HIS   F 1 123 ? 242.461 267.455 234.361 1.00 47.82  ? 135 HIS   A CE1    1 
ATOM   5527 N NE2    . HIS   F 1 123 ? 243.499 268.258 234.222 1.00 47.76  ? 135 HIS   A NE2    1 
ATOM   5528 N N      . MET   F 1 124 ? 247.424 264.844 233.170 1.00 43.51  ? 136 MET   A N      1 
ATOM   5529 C CA     . MET   F 1 124 ? 248.265 265.339 232.087 1.00 44.94  ? 136 MET   A CA     1 
ATOM   5530 C C      . MET   F 1 124 ? 248.281 264.367 230.914 1.00 44.67  ? 136 MET   A C      1 
ATOM   5531 O O      . MET   F 1 124 ? 248.330 264.786 229.753 1.00 42.22  ? 136 MET   A O      1 
ATOM   5532 C CB     . MET   F 1 124 ? 249.681 265.593 232.603 1.00 42.35  ? 136 MET   A CB     1 
ATOM   5533 C CG     . MET   F 1 124 ? 249.907 267.001 233.119 1.00 43.88  ? 136 MET   A CG     1 
ATOM   5534 S SD     . MET   F 1 124 ? 251.014 267.062 234.539 1.00 54.18  ? 136 MET   A SD     1 
ATOM   5535 C CE     . MET   F 1 124 ? 252.092 265.679 234.189 1.00 52.55  ? 136 MET   A CE     1 
ATOM   5536 N N      . MET   F 1 125 ? 248.241 263.063 231.199 1.00 47.16  ? 137 MET   A N      1 
ATOM   5537 C CA     . MET   F 1 125 ? 248.224 262.069 230.131 1.00 43.17  ? 137 MET   A CA     1 
ATOM   5538 C C      . MET   F 1 125 ? 246.953 262.177 229.298 1.00 43.51  ? 137 MET   A C      1 
ATOM   5539 O O      . MET   F 1 125 ? 246.987 262.000 228.075 1.00 44.11  ? 137 MET   A O      1 
ATOM   5540 C CB     . MET   F 1 125 ? 248.367 260.666 230.720 1.00 43.54  ? 137 MET   A CB     1 
ATOM   5541 C CG     . MET   F 1 125 ? 249.806 260.218 230.898 1.00 48.90  ? 137 MET   A CG     1 
ATOM   5542 S SD     . MET   F 1 125 ? 250.029 259.069 232.269 1.00 53.17  ? 137 MET   A SD     1 
ATOM   5543 C CE     . MET   F 1 125 ? 249.029 257.697 231.715 1.00 49.21  ? 137 MET   A CE     1 
ATOM   5544 N N      . ILE   F 1 126 ? 245.820 262.456 229.944 1.00 45.68  ? 138 ILE   A N      1 
ATOM   5545 C CA     . ILE   F 1 126 ? 244.568 262.622 229.210 1.00 44.23  ? 138 ILE   A CA     1 
ATOM   5546 C C      . ILE   F 1 126 ? 244.610 263.885 228.359 1.00 45.07  ? 138 ILE   A C      1 
ATOM   5547 O O      . ILE   F 1 126 ? 244.073 263.918 227.246 1.00 47.77  ? 138 ILE   A O      1 
ATOM   5548 C CB     . ILE   F 1 126 ? 243.374 262.630 230.181 1.00 44.91  ? 138 ILE   A CB     1 
ATOM   5549 C CG1    . ILE   F 1 126 ? 243.215 261.261 230.844 1.00 45.61  ? 138 ILE   A CG1    1 
ATOM   5550 C CG2    . ILE   F 1 126 ? 242.101 263.013 229.455 1.00 48.78  ? 138 ILE   A CG2    1 
ATOM   5551 C CD1    . ILE   F 1 126 ? 242.424 261.295 232.127 1.00 47.13  ? 138 ILE   A CD1    1 
ATOM   5552 N N      . TRP   F 1 127 ? 245.238 264.945 228.870 1.00 44.24  ? 139 TRP   A N      1 
ATOM   5553 C CA     . TRP   F 1 127 ? 245.365 266.174 228.093 1.00 44.34  ? 139 TRP   A CA     1 
ATOM   5554 C C      . TRP   F 1 127 ? 246.177 265.941 226.825 1.00 44.08  ? 139 TRP   A C      1 
ATOM   5555 O O      . TRP   F 1 127 ? 245.826 266.445 225.752 1.00 42.58  ? 139 TRP   A O      1 
ATOM   5556 C CB     . TRP   F 1 127 ? 245.990 267.268 228.961 1.00 42.43  ? 139 TRP   A CB     1 
ATOM   5557 C CG     . TRP   F 1 127 ? 246.917 268.208 228.247 1.00 43.10  ? 139 TRP   A CG     1 
ATOM   5558 C CD1    . TRP   F 1 127 ? 248.241 268.396 228.503 1.00 45.75  ? 139 TRP   A CD1    1 
ATOM   5559 C CD2    . TRP   F 1 127 ? 246.584 269.108 227.183 1.00 45.20  ? 139 TRP   A CD2    1 
ATOM   5560 N NE1    . TRP   F 1 127 ? 248.759 269.344 227.657 1.00 46.82  ? 139 TRP   A NE1    1 
ATOM   5561 C CE2    . TRP   F 1 127 ? 247.761 269.798 226.837 1.00 44.85  ? 139 TRP   A CE2    1 
ATOM   5562 C CE3    . TRP   F 1 127 ? 245.407 269.391 226.486 1.00 46.03  ? 139 TRP   A CE3    1 
ATOM   5563 C CZ2    . TRP   F 1 127 ? 247.795 270.752 225.826 1.00 43.21  ? 139 TRP   A CZ2    1 
ATOM   5564 C CZ3    . TRP   F 1 127 ? 245.444 270.339 225.484 1.00 44.48  ? 139 TRP   A CZ3    1 
ATOM   5565 C CH2    . TRP   F 1 127 ? 246.629 271.007 225.161 1.00 43.55  ? 139 TRP   A CH2    1 
ATOM   5566 N N      . HIS   F 1 128 ? 247.265 265.176 226.924 1.00 46.24  ? 140 HIS   A N      1 
ATOM   5567 C CA     . HIS   F 1 128 ? 248.067 264.881 225.742 1.00 43.87  ? 140 HIS   A CA     1 
ATOM   5568 C C      . HIS   F 1 128 ? 247.290 264.035 224.741 1.00 44.68  ? 140 HIS   A C      1 
ATOM   5569 O O      . HIS   F 1 128 ? 247.372 264.264 223.529 1.00 47.39  ? 140 HIS   A O      1 
ATOM   5570 C CB     . HIS   F 1 128 ? 249.362 264.182 226.149 1.00 42.35  ? 140 HIS   A CB     1 
ATOM   5571 C CG     . HIS   F 1 128 ? 250.338 265.081 226.838 1.00 43.69  ? 140 HIS   A CG     1 
ATOM   5572 N ND1    . HIS   F 1 128 ? 251.458 264.609 227.487 1.00 49.78  ? 140 HIS   A ND1    1 
ATOM   5573 C CD2    . HIS   F 1 128 ? 250.360 266.427 226.980 1.00 44.30  ? 140 HIS   A CD2    1 
ATOM   5574 C CE1    . HIS   F 1 128 ? 252.127 265.626 228.001 1.00 49.38  ? 140 HIS   A CE1    1 
ATOM   5575 N NE2    . HIS   F 1 128 ? 251.482 266.740 227.708 1.00 49.29  ? 140 HIS   A NE2    1 
ATOM   5576 N N      . SER   F 1 129 ? 246.537 263.046 225.226 1.00 44.35  ? 141 SER   A N      1 
ATOM   5577 C CA     . SER   F 1 129 ? 245.728 262.231 224.326 1.00 44.42  ? 141 SER   A CA     1 
ATOM   5578 C C      . SER   F 1 129 ? 244.680 263.076 223.614 1.00 46.06  ? 141 SER   A C      1 
ATOM   5579 O O      . SER   F 1 129 ? 244.460 262.920 222.408 1.00 47.32  ? 141 SER   A O      1 
ATOM   5580 C CB     . SER   F 1 129 ? 245.068 261.091 225.098 1.00 46.12  ? 141 SER   A CB     1 
ATOM   5581 O OG     . SER   F 1 129 ? 243.845 260.711 224.493 1.00 57.04  ? 141 SER   A OG     1 
ATOM   5582 N N      . ASN   F 1 130 ? 244.026 263.983 224.344 1.00 45.71  ? 142 ASN   A N      1 
ATOM   5583 C CA     . ASN   F 1 130 ? 243.039 264.857 223.721 1.00 43.84  ? 142 ASN   A CA     1 
ATOM   5584 C C      . ASN   F 1 130 ? 243.675 265.712 222.634 1.00 43.22  ? 142 ASN   A C      1 
ATOM   5585 O O      . ASN   F 1 130 ? 243.085 265.916 221.567 1.00 43.00  ? 142 ASN   A O      1 
ATOM   5586 C CB     . ASN   F 1 130 ? 242.379 265.743 224.778 1.00 45.63  ? 142 ASN   A CB     1 
ATOM   5587 C CG     . ASN   F 1 130 ? 241.412 264.981 225.659 1.00 48.31  ? 142 ASN   A CG     1 
ATOM   5588 O OD1    . ASN   F 1 130 ? 241.081 263.828 225.388 1.00 51.65  ? 142 ASN   A OD1    1 
ATOM   5589 N ND2    . ASN   F 1 130 ? 240.952 265.624 226.724 1.00 45.05  ? 142 ASN   A ND2    1 
ATOM   5590 N N      . LEU   F 1 131 ? 244.877 266.231 222.892 1.00 45.55  ? 143 LEU   A N      1 
ATOM   5591 C CA     . LEU   F 1 131 ? 245.572 267.029 221.888 1.00 46.86  ? 143 LEU   A CA     1 
ATOM   5592 C C      . LEU   F 1 131 ? 245.954 266.185 220.678 1.00 46.15  ? 143 LEU   A C      1 
ATOM   5593 O O      . LEU   F 1 131 ? 245.824 266.633 219.534 1.00 45.16  ? 143 LEU   A O      1 
ATOM   5594 C CB     . LEU   F 1 131 ? 246.810 267.680 222.503 1.00 46.45  ? 143 LEU   A CB     1 
ATOM   5595 C CG     . LEU   F 1 131 ? 247.636 268.568 221.576 1.00 46.90  ? 143 LEU   A CG     1 
ATOM   5596 C CD1    . LEU   F 1 131 ? 246.756 269.632 220.948 1.00 44.73  ? 143 LEU   A CD1    1 
ATOM   5597 C CD2    . LEU   F 1 131 ? 248.790 269.198 222.329 1.00 49.55  ? 143 LEU   A CD2    1 
ATOM   5598 N N      . ASN   F 1 132 ? 246.439 264.964 220.912 1.00 47.20  ? 144 ASN   A N      1 
ATOM   5599 C CA     . ASN   F 1 132 ? 246.800 264.090 219.800 1.00 45.18  ? 144 ASN   A CA     1 
ATOM   5600 C C      . ASN   F 1 132 ? 245.576 263.703 218.981 1.00 46.03  ? 144 ASN   A C      1 
ATOM   5601 O O      . ASN   F 1 132 ? 245.638 263.643 217.748 1.00 48.83  ? 144 ASN   A O      1 
ATOM   5602 C CB     . ASN   F 1 132 ? 247.515 262.843 220.318 1.00 46.94  ? 144 ASN   A CB     1 
ATOM   5603 C CG     . ASN   F 1 132 ? 248.938 263.123 220.751 1.00 51.71  ? 144 ASN   A CG     1 
ATOM   5604 O OD1    . ASN   F 1 132 ? 249.363 262.708 221.827 1.00 53.32  ? 144 ASN   A OD1    1 
ATOM   5605 N ND2    . ASN   F 1 132 ? 249.682 263.831 219.914 1.00 50.91  ? 144 ASN   A ND2    1 
ATOM   5606 N N      . ASP   F 1 133 ? 244.452 263.434 219.649 1.00 44.53  ? 145 ASP   A N      1 
ATOM   5607 C CA     . ASP   F 1 133 ? 243.245 263.034 218.933 1.00 44.79  ? 145 ASP   A CA     1 
ATOM   5608 C C      . ASP   F 1 133 ? 242.751 264.146 218.016 1.00 46.32  ? 145 ASP   A C      1 
ATOM   5609 O O      . ASP   F 1 133 ? 242.286 263.879 216.902 1.00 52.97  ? 145 ASP   A O      1 
ATOM   5610 C CB     . ASP   F 1 133 ? 242.152 262.631 219.923 1.00 45.86  ? 145 ASP   A CB     1 
ATOM   5611 C CG     . ASP   F 1 133 ? 242.434 261.301 220.593 1.00 48.28  ? 145 ASP   A CG     1 
ATOM   5612 O OD1    . ASP   F 1 133 ? 243.090 260.446 219.967 1.00 52.72  ? 145 ASP   A OD1    1 
ATOM   5613 O OD2    . ASP   F 1 133 ? 241.995 261.108 221.744 1.00 47.42  ? 145 ASP   A OD2    1 
ATOM   5614 N N      . ALA   F 1 134 ? 242.832 265.398 218.469 1.00 43.34  ? 146 ALA   A N      1 
ATOM   5615 C CA     . ALA   F 1 134 ? 242.344 266.507 217.658 1.00 45.77  ? 146 ALA   A CA     1 
ATOM   5616 C C      . ALA   F 1 134 ? 243.309 266.861 216.533 1.00 48.37  ? 146 ALA   A C      1 
ATOM   5617 O O      . ALA   F 1 134 ? 242.891 267.433 215.521 1.00 54.27  ? 146 ALA   A O      1 
ATOM   5618 C CB     . ALA   F 1 134 ? 242.087 267.728 218.539 1.00 44.66  ? 146 ALA   A CB     1 
ATOM   5619 N N      . THR   F 1 135 ? 244.592 266.533 216.684 1.00 47.23  ? 147 THR   A N      1 
ATOM   5620 C CA     . THR   F 1 135 ? 245.614 266.933 215.722 1.00 46.88  ? 147 THR   A CA     1 
ATOM   5621 C C      . THR   F 1 135 ? 245.907 265.844 214.693 1.00 47.02  ? 147 THR   A C      1 
ATOM   5622 O O      . THR   F 1 135 ? 245.916 266.111 213.489 1.00 49.04  ? 147 THR   A O      1 
ATOM   5623 C CB     . THR   F 1 135 ? 246.904 267.322 216.456 1.00 48.18  ? 147 THR   A CB     1 
ATOM   5624 O OG1    . THR   F 1 135 ? 246.631 268.379 217.382 1.00 53.26  ? 147 THR   A OG1    1 
ATOM   5625 C CG2    . THR   F 1 135 ? 247.953 267.790 215.467 1.00 49.31  ? 147 THR   A CG2    1 
ATOM   5626 N N      . TYR   F 1 136 ? 246.150 264.619 215.146 1.00 47.94  ? 148 TYR   A N      1 
ATOM   5627 C CA     . TYR   F 1 136 ? 246.617 263.545 214.282 1.00 49.04  ? 148 TYR   A CA     1 
ATOM   5628 C C      . TYR   F 1 136 ? 245.586 262.426 214.212 1.00 49.68  ? 148 TYR   A C      1 
ATOM   5629 O O      . TYR   F 1 136 ? 244.958 262.080 215.217 1.00 51.90  ? 148 TYR   A O      1 
ATOM   5630 C CB     . TYR   F 1 136 ? 247.957 262.999 214.780 1.00 47.38  ? 148 TYR   A CB     1 
ATOM   5631 C CG     . TYR   F 1 136 ? 249.037 264.052 214.845 1.00 48.33  ? 148 TYR   A CG     1 
ATOM   5632 C CD1    . TYR   F 1 136 ? 249.404 264.764 213.714 1.00 49.47  ? 148 TYR   A CD1    1 
ATOM   5633 C CD2    . TYR   F 1 136 ? 249.683 264.343 216.036 1.00 50.80  ? 148 TYR   A CD2    1 
ATOM   5634 C CE1    . TYR   F 1 136 ? 250.385 265.731 213.766 1.00 49.82  ? 148 TYR   A CE1    1 
ATOM   5635 C CE2    . TYR   F 1 136 ? 250.666 265.310 216.097 1.00 48.92  ? 148 TYR   A CE2    1 
ATOM   5636 C CZ     . TYR   F 1 136 ? 251.013 265.999 214.958 1.00 49.23  ? 148 TYR   A CZ     1 
ATOM   5637 O OH     . TYR   F 1 136 ? 251.991 266.963 215.009 1.00 53.23  ? 148 TYR   A OH     1 
ATOM   5638 N N      . GLN   F 1 137 ? 245.420 261.866 213.019 1.00 48.71  ? 149 GLN   A N      1 
ATOM   5639 C CA     . GLN   F 1 137 ? 244.457 260.804 212.758 1.00 51.93  ? 149 GLN   A CA     1 
ATOM   5640 C C      . GLN   F 1 137 ? 245.223 259.531 212.426 1.00 53.68  ? 149 GLN   A C      1 
ATOM   5641 O O      . GLN   F 1 137 ? 245.990 259.500 211.457 1.00 60.63  ? 149 GLN   A O      1 
ATOM   5642 C CB     . GLN   F 1 137 ? 243.522 261.206 211.619 1.00 51.64  ? 149 GLN   A CB     1 
ATOM   5643 C CG     . GLN   F 1 137 ? 242.716 260.085 211.011 1.00 54.75  ? 149 GLN   A CG     1 
ATOM   5644 C CD     . GLN   F 1 137 ? 241.763 260.587 209.947 1.00 61.25  ? 149 GLN   A CD     1 
ATOM   5645 O OE1    . GLN   F 1 137 ? 241.885 261.716 209.471 1.00 49.72  ? 149 GLN   A OE1    1 
ATOM   5646 N NE2    . GLN   F 1 137 ? 240.806 259.750 209.567 1.00 72.41  ? 149 GLN   A NE2    1 
ATOM   5647 N N      . ARG   F 1 138 ? 245.026 258.487 213.231 1.00 49.27  ? 150 ARG   A N      1 
ATOM   5648 C CA     . ARG   F 1 138 ? 245.837 257.274 213.135 1.00 51.55  ? 150 ARG   A CA     1 
ATOM   5649 C C      . ARG   F 1 138 ? 245.066 256.190 212.388 1.00 50.16  ? 150 ARG   A C      1 
ATOM   5650 O O      . ARG   F 1 138 ? 244.560 255.230 212.967 1.00 50.14  ? 150 ARG   A O      1 
ATOM   5651 C CB     . ARG   F 1 138 ? 246.268 256.806 214.522 1.00 51.70  ? 150 ARG   A CB     1 
ATOM   5652 C CG     . ARG   F 1 138 ? 245.236 257.015 215.607 1.00 49.11  ? 150 ARG   A CG     1 
ATOM   5653 C CD     . ARG   F 1 138 ? 245.873 256.893 216.975 1.00 49.72  ? 150 ARG   A CD     1 
ATOM   5654 N NE     . ARG   F 1 138 ? 246.315 255.533 217.255 1.00 51.87  ? 150 ARG   A NE     1 
ATOM   5655 C CZ     . ARG   F 1 138 ? 247.581 255.139 217.231 1.00 47.32  ? 150 ARG   A CZ     1 
ATOM   5656 N NH1    . ARG   F 1 138 ? 248.559 255.976 216.933 1.00 44.73  ? 150 ARG   A NH1    1 
ATOM   5657 N NH2    . ARG   F 1 138 ? 247.871 253.874 217.516 1.00 48.13  ? 150 ARG   A NH2    1 
ATOM   5658 N N      . THR   F 1 139 ? 244.995 256.347 211.067 1.00 53.08  ? 151 THR   A N      1 
ATOM   5659 C CA     . THR   F 1 139 ? 244.467 255.286 210.223 1.00 52.84  ? 151 THR   A CA     1 
ATOM   5660 C C      . THR   F 1 139 ? 245.482 254.176 209.993 1.00 50.05  ? 151 THR   A C      1 
ATOM   5661 O O      . THR   F 1 139 ? 245.088 253.051 209.670 1.00 51.27  ? 151 THR   A O      1 
ATOM   5662 C CB     . THR   F 1 139 ? 244.012 255.850 208.875 1.00 51.10  ? 151 THR   A CB     1 
ATOM   5663 O OG1    . THR   F 1 139 ? 245.113 255.849 207.961 1.00 54.27  ? 151 THR   A OG1    1 
ATOM   5664 C CG2    . THR   F 1 139 ? 243.501 257.268 209.039 1.00 50.74  ? 151 THR   A CG2    1 
ATOM   5665 N N      . ARG   F 1 140 ? 246.774 254.471 210.157 1.00 48.31  ? 152 ARG   A N      1 
ATOM   5666 C CA     . ARG   F 1 140 ? 247.802 253.453 209.970 1.00 49.16  ? 152 ARG   A CA     1 
ATOM   5667 C C      . ARG   F 1 140 ? 247.646 252.320 210.973 1.00 48.82  ? 152 ARG   A C      1 
ATOM   5668 O O      . ARG   F 1 140 ? 247.771 251.143 210.616 1.00 49.08  ? 152 ARG   A O      1 
ATOM   5669 C CB     . ARG   F 1 140 ? 249.185 254.086 210.094 1.00 49.45  ? 152 ARG   A CB     1 
ATOM   5670 C CG     . ARG   F 1 140 ? 250.008 254.034 208.829 1.00 51.59  ? 152 ARG   A CG     1 
ATOM   5671 C CD     . ARG   F 1 140 ? 251.310 254.780 209.014 1.00 50.29  ? 152 ARG   A CD     1 
ATOM   5672 N NE     . ARG   F 1 140 ? 251.112 256.222 208.954 1.00 47.70  ? 152 ARG   A NE     1 
ATOM   5673 C CZ     . ARG   F 1 140 ? 252.075 257.116 209.121 1.00 60.10  ? 152 ARG   A CZ     1 
ATOM   5674 N NH1    . ARG   F 1 140 ? 253.322 256.752 209.365 1.00 63.10  ? 152 ARG   A NH1    1 
ATOM   5675 N NH2    . ARG   F 1 140 ? 251.778 258.410 209.042 1.00 68.45  ? 152 ARG   A NH2    1 
ATOM   5676 N N      . ALA   F 1 141 ? 247.382 252.655 212.237 1.00 48.40  ? 153 ALA   A N      1 
ATOM   5677 C CA     . ALA   F 1 141 ? 247.139 251.619 213.232 1.00 46.89  ? 153 ALA   A CA     1 
ATOM   5678 C C      . ALA   F 1 141 ? 245.841 250.876 212.956 1.00 48.38  ? 153 ALA   A C      1 
ATOM   5679 O O      . ALA   F 1 141 ? 245.766 249.662 213.169 1.00 52.33  ? 153 ALA   A O      1 
ATOM   5680 C CB     . ALA   F 1 141 ? 247.117 252.231 214.631 1.00 49.66  ? 153 ALA   A CB     1 
ATOM   5681 N N      . LEU   F 1 142 ? 244.817 251.584 212.479 1.00 48.67  ? 154 LEU   A N      1 
ATOM   5682 C CA     . LEU   F 1 142 ? 243.554 250.934 212.148 1.00 48.47  ? 154 LEU   A CA     1 
ATOM   5683 C C      . LEU   F 1 142 ? 243.722 249.967 210.984 1.00 49.81  ? 154 LEU   A C      1 
ATOM   5684 O O      . LEU   F 1 142 ? 243.211 248.842 211.018 1.00 50.61  ? 154 LEU   A O      1 
ATOM   5685 C CB     . LEU   F 1 142 ? 242.497 251.989 211.824 1.00 49.99  ? 154 LEU   A CB     1 
ATOM   5686 C CG     . LEU   F 1 142 ? 241.819 252.670 213.011 1.00 49.92  ? 154 LEU   A CG     1 
ATOM   5687 C CD1    . LEU   F 1 142 ? 241.069 253.907 212.557 1.00 51.55  ? 154 LEU   A CD1    1 
ATOM   5688 C CD2    . LEU   F 1 142 ? 240.885 251.706 213.716 1.00 55.22  ? 154 LEU   A CD2    1 
ATOM   5689 N N      . VAL   F 1 143 ? 244.430 250.393 209.936 1.00 50.63  ? 155 VAL   A N      1 
ATOM   5690 C CA     . VAL   F 1 143 ? 244.659 249.519 208.791 1.00 52.10  ? 155 VAL   A CA     1 
ATOM   5691 C C      . VAL   F 1 143 ? 245.614 248.392 209.154 1.00 49.32  ? 155 VAL   A C      1 
ATOM   5692 O O      . VAL   F 1 143 ? 245.457 247.259 208.684 1.00 50.86  ? 155 VAL   A O      1 
ATOM   5693 C CB     . VAL   F 1 143 ? 245.176 250.336 207.593 1.00 49.98  ? 155 VAL   A CB     1 
ATOM   5694 C CG1    . VAL   F 1 143 ? 246.507 250.980 207.926 1.00 50.18  ? 155 VAL   A CG1    1 
ATOM   5695 C CG2    . VAL   F 1 143 ? 245.302 249.453 206.366 1.00 51.42  ? 155 VAL   A CG2    1 
ATOM   5696 N N      . ARG   F 1 144 ? 246.615 248.677 209.987 1.00 48.19  ? 156 ARG   A N      1 
ATOM   5697 C CA     . ARG   F 1 144 ? 247.586 247.655 210.357 1.00 49.68  ? 156 ARG   A CA     1 
ATOM   5698 C C      . ARG   F 1 144 ? 246.936 246.530 211.153 1.00 51.37  ? 156 ARG   A C      1 
ATOM   5699 O O      . ARG   F 1 144 ? 247.278 245.357 210.971 1.00 57.06  ? 156 ARG   A O      1 
ATOM   5700 C CB     . ARG   F 1 144 ? 248.728 248.289 211.148 1.00 50.59  ? 156 ARG   A CB     1 
ATOM   5701 C CG     . ARG   F 1 144 ? 250.104 247.781 210.774 1.00 48.89  ? 156 ARG   A CG     1 
ATOM   5702 C CD     . ARG   F 1 144 ? 251.057 247.897 211.942 1.00 49.55  ? 156 ARG   A CD     1 
ATOM   5703 N NE     . ARG   F 1 144 ? 251.691 249.208 211.977 1.00 65.36  ? 156 ARG   A NE     1 
ATOM   5704 C CZ     . ARG   F 1 144 ? 252.426 249.658 212.984 1.00 80.05  ? 156 ARG   A CZ     1 
ATOM   5705 N NH1    . ARG   F 1 144 ? 252.648 248.922 214.060 1.00 82.29  ? 156 ARG   A NH1    1 
ATOM   5706 N NH2    . ARG   F 1 144 ? 252.950 250.878 212.910 1.00 76.11  ? 156 ARG   A NH2    1 
ATOM   5707 N N      . THR   F 1 145 ? 245.999 246.864 212.040 1.00 47.99  ? 157 THR   A N      1 
ATOM   5708 C CA     . THR   F 1 145 ? 245.338 245.851 212.851 1.00 50.43  ? 157 THR   A CA     1 
ATOM   5709 C C      . THR   F 1 145 ? 244.191 245.162 212.127 1.00 54.18  ? 157 THR   A C      1 
ATOM   5710 O O      . THR   F 1 145 ? 243.624 244.208 212.670 1.00 60.79  ? 157 THR   A O      1 
ATOM   5711 C CB     . THR   F 1 145 ? 244.815 246.462 214.152 1.00 51.86  ? 157 THR   A CB     1 
ATOM   5712 O OG1    . THR   F 1 145 ? 243.953 247.565 213.852 1.00 56.80  ? 157 THR   A OG1    1 
ATOM   5713 C CG2    . THR   F 1 145 ? 245.968 246.948 215.010 1.00 53.59  ? 157 THR   A CG2    1 
ATOM   5714 N N      . GLY   F 1 146 ? 243.835 245.613 210.928 1.00 51.52  ? 158 GLY   A N      1 
ATOM   5715 C CA     . GLY   F 1 146 ? 242.773 245.000 210.161 1.00 53.42  ? 158 GLY   A CA     1 
ATOM   5716 C C      . GLY   F 1 146 ? 241.424 245.669 210.281 1.00 53.38  ? 158 GLY   A C      1 
ATOM   5717 O O      . GLY   F 1 146 ? 240.453 245.170 209.700 1.00 58.30  ? 158 GLY   A O      1 
ATOM   5718 N N      . MET   F 1 147 ? 241.329 246.772 211.012 1.00 51.74  ? 159 MET   A N      1 
ATOM   5719 C CA     . MET   F 1 147 ? 240.077 247.497 211.151 1.00 52.59  ? 159 MET   A CA     1 
ATOM   5720 C C      . MET   F 1 147 ? 239.932 248.523 210.036 1.00 53.59  ? 159 MET   A C      1 
ATOM   5721 O O      . MET   F 1 147 ? 240.914 249.081 209.542 1.00 55.69  ? 159 MET   A O      1 
ATOM   5722 C CB     . MET   F 1 147 ? 239.999 248.191 212.511 1.00 52.28  ? 159 MET   A CB     1 
ATOM   5723 C CG     . MET   F 1 147 ? 240.706 247.453 213.630 1.00 55.93  ? 159 MET   A CG     1 
ATOM   5724 S SD     . MET   F 1 147 ? 240.649 248.359 215.184 1.00 65.01  ? 159 MET   A SD     1 
ATOM   5725 C CE     . MET   F 1 147 ? 238.973 248.984 215.142 1.00 55.03  ? 159 MET   A CE     1 
ATOM   5726 N N      . ASP   F 1 148 ? 238.693 248.760 209.642 1.00 55.28  ? 160 ASP   A N      1 
ATOM   5727 C CA     . ASP   F 1 148 ? 238.419 249.725 208.588 1.00 56.49  ? 160 ASP   A CA     1 
ATOM   5728 C C      . ASP   F 1 148 ? 238.765 251.129 209.072 1.00 58.66  ? 160 ASP   A C      1 
ATOM   5729 O O      . ASP   F 1 148 ? 238.306 251.541 210.143 1.00 62.69  ? 160 ASP   A O      1 
ATOM   5730 C CB     . ASP   F 1 148 ? 236.953 249.643 208.175 1.00 56.85  ? 160 ASP   A CB     1 
ATOM   5731 C CG     . ASP   F 1 148 ? 236.447 250.928 207.566 1.00 64.76  ? 160 ASP   A CG     1 
ATOM   5732 O OD1    . ASP   F 1 148 ? 237.170 251.516 206.737 1.00 73.28  ? 160 ASP   A OD1    1 
ATOM   5733 O OD2    . ASP   F 1 148 ? 235.326 251.348 207.917 1.00 63.59  ? 160 ASP   A OD2    1 
ATOM   5734 N N      . PRO   F 1 149 ? 239.564 251.892 208.321 1.00 58.51  ? 161 PRO   A N      1 
ATOM   5735 C CA     . PRO   F 1 149 ? 239.959 253.232 208.779 1.00 57.09  ? 161 PRO   A CA     1 
ATOM   5736 C C      . PRO   F 1 149 ? 238.812 254.225 208.877 1.00 55.35  ? 161 PRO   A C      1 
ATOM   5737 O O      . PRO   F 1 149 ? 239.044 255.365 209.293 1.00 57.85  ? 161 PRO   A O      1 
ATOM   5738 C CB     . PRO   F 1 149 ? 240.976 253.678 207.716 1.00 57.24  ? 161 PRO   A CB     1 
ATOM   5739 C CG     . PRO   F 1 149 ? 240.685 252.832 206.528 1.00 60.35  ? 161 PRO   A CG     1 
ATOM   5740 C CD     . PRO   F 1 149 ? 240.244 251.515 207.073 1.00 61.86  ? 161 PRO   A CD     1 
ATOM   5741 N N      . ARG   F 1 150 ? 237.588 253.844 208.512 1.00 57.06  ? 162 ARG   A N      1 
ATOM   5742 C CA     . ARG   F 1 150 ? 236.472 254.780 208.567 1.00 58.23  ? 162 ARG   A CA     1 
ATOM   5743 C C      . ARG   F 1 150 ? 235.969 255.024 209.983 1.00 60.29  ? 162 ARG   A C      1 
ATOM   5744 O O      . ARG   F 1 150 ? 235.315 256.045 210.220 1.00 61.32  ? 162 ARG   A O      1 
ATOM   5745 C CB     . ARG   F 1 150 ? 235.317 254.285 207.695 1.00 62.31  ? 162 ARG   A CB     1 
ATOM   5746 C CG     . ARG   F 1 150 ? 235.716 253.917 206.278 1.00 62.84  ? 162 ARG   A CG     1 
ATOM   5747 C CD     . ARG   F 1 150 ? 234.592 254.192 205.296 1.00 60.50  ? 162 ARG   A CD     1 
ATOM   5748 N NE     . ARG   F 1 150 ? 234.277 255.612 205.217 1.00 77.37  ? 162 ARG   A NE     1 
ATOM   5749 C CZ     . ARG   F 1 150 ? 234.551 256.384 204.174 1.00 85.26  ? 162 ARG   A CZ     1 
ATOM   5750 N NH1    . ARG   F 1 150 ? 235.144 255.902 203.095 1.00 85.05  ? 162 ARG   A NH1    1 
ATOM   5751 N NH2    . ARG   F 1 150 ? 234.222 257.672 204.215 1.00 79.59  ? 162 ARG   A NH2    1 
ATOM   5752 N N      . MET   F 1 151 ? 236.243 254.124 210.928 1.00 56.88  ? 163 MET   A N      1 
ATOM   5753 C CA     . MET   F 1 151 ? 235.817 254.334 212.312 1.00 53.80  ? 163 MET   A CA     1 
ATOM   5754 C C      . MET   F 1 151 ? 236.908 255.083 213.078 1.00 51.87  ? 163 MET   A C      1 
ATOM   5755 O O      . MET   F 1 151 ? 237.560 254.567 213.986 1.00 51.73  ? 163 MET   A O      1 
ATOM   5756 C CB     . MET   F 1 151 ? 235.459 253.013 212.983 1.00 56.43  ? 163 MET   A CB     1 
ATOM   5757 C CG     . MET   F 1 151 ? 236.542 251.954 212.985 1.00 56.20  ? 163 MET   A CG     1 
ATOM   5758 S SD     . MET   F 1 151 ? 235.811 250.305 212.965 1.00 63.45  ? 163 MET   A SD     1 
ATOM   5759 C CE     . MET   F 1 151 ? 236.968 249.420 211.936 1.00 58.78  ? 163 MET   A CE     1 
ATOM   5760 N N      . CYS   F 1 152 ? 237.091 256.340 212.687 1.00 55.84  ? 164 CYS   A N      1 
ATOM   5761 C CA     . CYS   F 1 152 ? 237.999 257.239 213.381 1.00 54.56  ? 164 CYS   A CA     1 
ATOM   5762 C C      . CYS   F 1 152 ? 237.322 257.996 214.514 1.00 53.60  ? 164 CYS   A C      1 
ATOM   5763 O O      . CYS   F 1 152 ? 238.012 258.659 215.294 1.00 57.33  ? 164 CYS   A O      1 
ATOM   5764 C CB     . CYS   F 1 152 ? 238.618 258.231 212.391 1.00 51.61  ? 164 CYS   A CB     1 
ATOM   5765 S SG     . CYS   F 1 152 ? 237.643 259.722 212.121 1.00 83.32  ? 164 CYS   A SG     1 
ATOM   5766 N N      . SER   F 1 153 ? 235.998 257.904 214.627 1.00 49.88  ? 165 SER   A N      1 
ATOM   5767 C CA     . SER   F 1 153 ? 235.272 258.521 215.728 1.00 49.17  ? 165 SER   A CA     1 
ATOM   5768 C C      . SER   F 1 153 ? 235.348 257.710 217.013 1.00 48.89  ? 165 SER   A C      1 
ATOM   5769 O O      . SER   F 1 153 ? 235.000 258.233 218.076 1.00 51.14  ? 165 SER   A O      1 
ATOM   5770 C CB     . SER   F 1 153 ? 233.805 258.718 215.341 1.00 48.59  ? 165 SER   A CB     1 
ATOM   5771 O OG     . SER   F 1 153 ? 233.668 259.735 214.367 1.00 63.21  ? 165 SER   A OG     1 
ATOM   5772 N N      . LEU   F 1 154 ? 235.783 256.454 216.941 1.00 49.27  ? 166 LEU   A N      1 
ATOM   5773 C CA     . LEU   F 1 154 ? 235.860 255.577 218.101 1.00 45.12  ? 166 LEU   A CA     1 
ATOM   5774 C C      . LEU   F 1 154 ? 237.278 255.452 218.643 1.00 48.21  ? 166 LEU   A C      1 
ATOM   5775 O O      . LEU   F 1 154 ? 237.513 254.673 219.571 1.00 52.03  ? 166 LEU   A O      1 
ATOM   5776 C CB     . LEU   F 1 154 ? 235.311 254.196 217.747 1.00 45.03  ? 166 LEU   A CB     1 
ATOM   5777 C CG     . LEU   F 1 154 ? 234.020 254.192 216.932 1.00 43.05  ? 166 LEU   A CG     1 
ATOM   5778 C CD1    . LEU   F 1 154 ? 233.966 252.975 216.028 1.00 45.44  ? 166 LEU   A CD1    1 
ATOM   5779 C CD2    . LEU   F 1 154 ? 232.811 254.244 217.847 1.00 41.75  ? 166 LEU   A CD2    1 
ATOM   5780 N N      . MET   F 1 155 ? 238.223 256.209 218.090 1.00 50.91  ? 167 MET   A N      1 
ATOM   5781 C CA     . MET   F 1 155 ? 239.621 256.140 218.487 1.00 49.51  ? 167 MET   A CA     1 
ATOM   5782 C C      . MET   F 1 155 ? 239.952 257.102 219.619 1.00 50.38  ? 167 MET   A C      1 
ATOM   5783 O O      . MET   F 1 155 ? 241.113 257.491 219.775 1.00 54.87  ? 167 MET   A O      1 
ATOM   5784 C CB     . MET   F 1 155 ? 240.521 256.416 217.285 1.00 54.65  ? 167 MET   A CB     1 
ATOM   5785 C CG     . MET   F 1 155 ? 240.572 255.290 216.276 1.00 55.45  ? 167 MET   A CG     1 
ATOM   5786 S SD     . MET   F 1 155 ? 241.096 253.737 217.016 1.00 66.56  ? 167 MET   A SD     1 
ATOM   5787 C CE     . MET   F 1 155 ? 239.630 252.751 216.764 1.00 55.74  ? 167 MET   A CE     1 
ATOM   5788 N N      . GLN   F 1 156 ? 238.958 257.493 220.410 1.00 47.29  ? 168 GLN   A N      1 
ATOM   5789 C CA     . GLN   F 1 156 ? 239.189 258.434 221.495 1.00 47.17  ? 168 GLN   A CA     1 
ATOM   5790 C C      . GLN   F 1 156 ? 240.175 257.848 222.497 1.00 46.08  ? 168 GLN   A C      1 
ATOM   5791 O O      . GLN   F 1 156 ? 239.986 256.734 222.993 1.00 47.03  ? 168 GLN   A O      1 
ATOM   5792 C CB     . GLN   F 1 156 ? 237.867 258.777 222.178 1.00 47.79  ? 168 GLN   A CB     1 
ATOM   5793 C CG     . GLN   F 1 156 ? 237.994 259.186 223.632 1.00 48.63  ? 168 GLN   A CG     1 
ATOM   5794 C CD     . GLN   F 1 156 ? 237.972 260.685 223.823 1.00 45.19  ? 168 GLN   A CD     1 
ATOM   5795 O OE1    . GLN   F 1 156 ? 237.974 261.446 222.858 1.00 50.36  ? 168 GLN   A OE1    1 
ATOM   5796 N NE2    . GLN   F 1 156 ? 237.940 261.119 225.075 1.00 43.77  ? 168 GLN   A NE2    1 
ATOM   5797 N N      . GLY   F 1 157 ? 241.227 258.600 222.794 1.00 46.21  ? 169 GLY   A N      1 
ATOM   5798 C CA     . GLY   F 1 157 ? 242.241 258.140 223.726 1.00 46.99  ? 169 GLY   A CA     1 
ATOM   5799 C C      . GLY   F 1 157 ? 243.011 256.923 223.262 1.00 47.09  ? 169 GLY   A C      1 
ATOM   5800 O O      . GLY   F 1 157 ? 243.352 256.062 224.082 1.00 48.42  ? 169 GLY   A O      1 
ATOM   5801 N N      . SER   F 1 158 ? 243.299 256.828 221.964 1.00 49.92  ? 170 SER   A N      1 
ATOM   5802 C CA     . SER   F 1 158 ? 244.081 255.708 221.457 1.00 49.90  ? 170 SER   A CA     1 
ATOM   5803 C C      . SER   F 1 158 ? 245.563 255.837 221.774 1.00 53.54  ? 170 SER   A C      1 
ATOM   5804 O O      . SER   F 1 158 ? 246.273 254.827 221.767 1.00 56.44  ? 170 SER   A O      1 
ATOM   5805 C CB     . SER   F 1 158 ? 243.896 255.571 219.946 1.00 50.71  ? 170 SER   A CB     1 
ATOM   5806 O OG     . SER   F 1 158 ? 243.835 256.840 219.322 1.00 59.01  ? 170 SER   A OG     1 
ATOM   5807 N N      . THR   F 1 159 ? 246.042 257.046 222.046 1.00 50.83  ? 171 THR   A N      1 
ATOM   5808 C CA     . THR   F 1 159 ? 247.448 257.280 222.347 1.00 50.00  ? 171 THR   A CA     1 
ATOM   5809 C C      . THR   F 1 159 ? 247.760 257.217 223.836 1.00 51.05  ? 171 THR   A C      1 
ATOM   5810 O O      . THR   F 1 159 ? 248.919 257.399 224.217 1.00 54.25  ? 171 THR   A O      1 
ATOM   5811 C CB     . THR   F 1 159 ? 247.884 258.637 221.790 1.00 51.15  ? 171 THR   A CB     1 
ATOM   5812 O OG1    . THR   F 1 159 ? 246.959 259.646 222.212 1.00 55.23  ? 171 THR   A OG1    1 
ATOM   5813 C CG2    . THR   F 1 159 ? 247.922 258.599 220.275 1.00 49.33  ? 171 THR   A CG2    1 
ATOM   5814 N N      . LEU   F 1 160 ? 246.768 256.966 224.676 1.00 49.37  ? 172 LEU   A N      1 
ATOM   5815 C CA     . LEU   F 1 160 ? 247.001 256.913 226.113 1.00 46.98  ? 172 LEU   A CA     1 
ATOM   5816 C C      . LEU   F 1 160 ? 247.851 255.697 226.464 1.00 50.65  ? 172 LEU   A C      1 
ATOM   5817 O O      . LEU   F 1 160 ? 247.557 254.588 226.004 1.00 57.20  ? 172 LEU   A O      1 
ATOM   5818 C CB     . LEU   F 1 160 ? 245.676 256.856 226.868 1.00 45.04  ? 172 LEU   A CB     1 
ATOM   5819 C CG     . LEU   F 1 160 ? 245.081 258.185 227.329 1.00 47.49  ? 172 LEU   A CG     1 
ATOM   5820 C CD1    . LEU   F 1 160 ? 243.633 258.001 227.740 1.00 45.49  ? 172 LEU   A CD1    1 
ATOM   5821 C CD2    . LEU   F 1 160 ? 245.892 258.767 228.468 1.00 50.00  ? 172 LEU   A CD2    1 
ATOM   5822 N N      . PRO   F 1 161 ? 248.904 255.858 227.259 1.00 51.95  ? 173 PRO   A N      1 
ATOM   5823 C CA     . PRO   F 1 161 ? 249.675 254.694 227.706 1.00 52.33  ? 173 PRO   A CA     1 
ATOM   5824 C C      . PRO   F 1 161 ? 248.878 253.844 228.684 1.00 50.51  ? 173 PRO   A C      1 
ATOM   5825 O O      . PRO   F 1 161 ? 247.912 254.293 229.303 1.00 52.00  ? 173 PRO   A O      1 
ATOM   5826 C CB     . PRO   F 1 161 ? 250.903 255.313 228.380 1.00 51.29  ? 173 PRO   A CB     1 
ATOM   5827 C CG     . PRO   F 1 161 ? 250.479 256.683 228.767 1.00 48.57  ? 173 PRO   A CG     1 
ATOM   5828 C CD     . PRO   F 1 161 ? 249.452 257.125 227.771 1.00 49.05  ? 173 PRO   A CD     1 
ATOM   5829 N N      . ARG   F 1 162 ? 249.299 252.584 228.812 1.00 47.51  ? 174 ARG   A N      1 
ATOM   5830 C CA     . ARG   F 1 162 ? 248.617 251.658 229.709 1.00 48.78  ? 174 ARG   A CA     1 
ATOM   5831 C C      . ARG   F 1 162 ? 248.746 252.053 231.172 1.00 49.33  ? 174 ARG   A C      1 
ATOM   5832 O O      . ARG   F 1 162 ? 248.019 251.509 232.008 1.00 48.85  ? 174 ARG   A O      1 
ATOM   5833 C CB     . ARG   F 1 162 ? 249.151 250.237 229.512 1.00 48.90  ? 174 ARG   A CB     1 
ATOM   5834 C CG     . ARG   F 1 162 ? 250.646 250.105 229.718 1.00 57.74  ? 174 ARG   A CG     1 
ATOM   5835 C CD     . ARG   F 1 162 ? 251.099 248.653 229.860 1.00 64.13  ? 174 ARG   A CD     1 
ATOM   5836 N NE     . ARG   F 1 162 ? 250.563 247.768 228.832 1.00 57.32  ? 174 ARG   A NE     1 
ATOM   5837 C CZ     . ARG   F 1 162 ? 249.375 247.181 228.885 1.00 58.52  ? 174 ARG   A CZ     1 
ATOM   5838 N NH1    . ARG   F 1 162 ? 248.564 247.353 229.915 1.00 63.81  ? 174 ARG   A NH1    1 
ATOM   5839 N NH2    . ARG   F 1 162 ? 248.996 246.393 227.884 1.00 57.58  ? 174 ARG   A NH2    1 
ATOM   5840 N N      . ARG   F 1 163 ? 249.647 252.981 231.500 1.00 51.49  ? 175 ARG   A N      1 
ATOM   5841 C CA     . ARG   F 1 163 ? 249.813 253.411 232.882 1.00 50.29  ? 175 ARG   A CA     1 
ATOM   5842 C C      . ARG   F 1 163 ? 248.564 254.082 233.434 1.00 51.63  ? 175 ARG   A C      1 
ATOM   5843 O O      . ARG   F 1 163 ? 248.349 254.061 234.650 1.00 57.05  ? 175 ARG   A O      1 
ATOM   5844 C CB     . ARG   F 1 163 ? 251.004 254.361 232.986 1.00 46.68  ? 175 ARG   A CB     1 
ATOM   5845 C CG     . ARG   F 1 163 ? 252.263 253.815 232.350 1.00 50.63  ? 175 ARG   A CG     1 
ATOM   5846 C CD     . ARG   F 1 163 ? 253.090 254.913 231.714 1.00 49.45  ? 175 ARG   A CD     1 
ATOM   5847 N NE     . ARG   F 1 163 ? 253.377 255.998 232.642 1.00 47.14  ? 175 ARG   A NE     1 
ATOM   5848 C CZ     . ARG   F 1 163 ? 253.936 257.148 232.293 1.00 49.04  ? 175 ARG   A CZ     1 
ATOM   5849 N NH1    . ARG   F 1 163 ? 254.282 257.395 231.041 1.00 43.22  ? 175 ARG   A NH1    1 
ATOM   5850 N NH2    . ARG   F 1 163 ? 254.152 258.073 233.222 1.00 52.40  ? 175 ARG   A NH2    1 
ATOM   5851 N N      . SER   F 1 164 ? 247.739 254.678 232.576 1.00 49.37  ? 176 SER   A N      1 
ATOM   5852 C CA     . SER   F 1 164 ? 246.509 255.337 233.010 1.00 49.63  ? 176 SER   A CA     1 
ATOM   5853 C C      . SER   F 1 164 ? 245.410 254.288 233.096 1.00 54.43  ? 176 SER   A C      1 
ATOM   5854 O O      . SER   F 1 164 ? 244.682 254.037 232.136 1.00 61.60  ? 176 SER   A O      1 
ATOM   5855 C CB     . SER   F 1 164 ? 246.133 256.462 232.055 1.00 49.64  ? 176 SER   A CB     1 
ATOM   5856 O OG     . SER   F 1 164 ? 246.056 255.992 230.723 1.00 45.22  ? 176 SER   A OG     1 
ATOM   5857 N N      . GLY   F 1 165 ? 245.287 253.668 234.261 1.00 48.94  ? 177 GLY   A N      1 
ATOM   5858 C CA     . GLY   F 1 165 ? 244.250 252.690 234.511 1.00 47.06  ? 177 GLY   A CA     1 
ATOM   5859 C C      . GLY   F 1 165 ? 243.038 253.342 235.148 1.00 52.78  ? 177 GLY   A C      1 
ATOM   5860 O O      . GLY   F 1 165 ? 243.131 254.415 235.737 1.00 57.14  ? 177 GLY   A O      1 
ATOM   5861 N N      . ALA   F 1 166 ? 241.891 252.680 235.023 1.00 51.59  ? 178 ALA   A N      1 
ATOM   5862 C CA     . ALA   F 1 166 ? 240.658 253.226 235.573 1.00 51.42  ? 178 ALA   A CA     1 
ATOM   5863 C C      . ALA   F 1 166 ? 240.348 254.572 234.934 1.00 52.19  ? 178 ALA   A C      1 
ATOM   5864 O O      . ALA   F 1 166 ? 239.520 254.656 234.022 1.00 59.25  ? 178 ALA   A O      1 
ATOM   5865 C CB     . ALA   F 1 166 ? 240.760 253.363 237.092 1.00 53.98  ? 178 ALA   A CB     1 
ATOM   5866 N N      . ALA   F 1 167 ? 241.006 255.631 235.409 1.00 47.98  ? 179 ALA   A N      1 
ATOM   5867 C CA     . ALA   F 1 167 ? 240.768 256.960 234.856 1.00 47.42  ? 179 ALA   A CA     1 
ATOM   5868 C C      . ALA   F 1 167 ? 241.037 256.986 233.357 1.00 47.69  ? 179 ALA   A C      1 
ATOM   5869 O O      . ALA   F 1 167 ? 240.244 257.532 232.581 1.00 47.62  ? 179 ALA   A O      1 
ATOM   5870 C CB     . ALA   F 1 167 ? 241.635 257.991 235.578 1.00 46.97  ? 179 ALA   A CB     1 
ATOM   5871 N N      . GLY   F 1 168 ? 242.153 256.397 232.931 1.00 44.74  ? 180 GLY   A N      1 
ATOM   5872 C CA     . GLY   F 1 168 ? 242.461 256.364 231.512 1.00 44.74  ? 180 GLY   A CA     1 
ATOM   5873 C C      . GLY   F 1 168 ? 241.461 255.551 230.714 1.00 44.73  ? 180 GLY   A C      1 
ATOM   5874 O O      . GLY   F 1 168 ? 241.043 255.957 229.627 1.00 46.57  ? 180 GLY   A O      1 
ATOM   5875 N N      . ALA   F 1 169 ? 241.059 254.395 231.243 1.00 46.94  ? 181 ALA   A N      1 
ATOM   5876 C CA     . ALA   F 1 169 ? 240.125 253.539 230.523 1.00 47.94  ? 181 ALA   A CA     1 
ATOM   5877 C C      . ALA   F 1 169 ? 238.746 254.173 230.416 1.00 45.81  ? 181 ALA   A C      1 
ATOM   5878 O O      . ALA   F 1 169 ? 238.032 253.940 229.435 1.00 48.30  ? 181 ALA   A O      1 
ATOM   5879 C CB     . ALA   F 1 169 ? 240.030 252.176 231.206 1.00 49.32  ? 181 ALA   A CB     1 
ATOM   5880 N N      . ALA   F 1 170 ? 238.353 254.973 231.408 1.00 44.40  ? 182 ALA   A N      1 
ATOM   5881 C CA     . ALA   F 1 170 ? 237.045 255.615 231.361 1.00 42.31  ? 182 ALA   A CA     1 
ATOM   5882 C C      . ALA   F 1 170 ? 236.947 256.586 230.193 1.00 45.00  ? 182 ALA   A C      1 
ATOM   5883 O O      . ALA   F 1 170 ? 235.903 256.676 229.538 1.00 46.94  ? 182 ALA   A O      1 
ATOM   5884 C CB     . ALA   F 1 170 ? 236.767 256.333 232.681 1.00 38.86  ? 182 ALA   A CB     1 
ATOM   5885 N N      . VAL   F 1 171 ? 238.026 257.322 229.914 1.00 45.88  ? 183 VAL   A N      1 
ATOM   5886 C CA     . VAL   F 1 171 ? 237.990 258.343 228.870 1.00 46.80  ? 183 VAL   A CA     1 
ATOM   5887 C C      . VAL   F 1 171 ? 238.265 257.795 227.481 1.00 45.55  ? 183 VAL   A C      1 
ATOM   5888 O O      . VAL   F 1 171 ? 237.997 258.487 226.492 1.00 46.32  ? 183 VAL   A O      1 
ATOM   5889 C CB     . VAL   F 1 171 ? 239.005 259.462 229.164 1.00 46.54  ? 183 VAL   A CB     1 
ATOM   5890 C CG1    . VAL   F 1 171 ? 239.044 260.449 228.013 1.00 44.58  ? 183 VAL   A CG1    1 
ATOM   5891 C CG2    . VAL   F 1 171 ? 238.655 260.164 230.462 1.00 51.35  ? 183 VAL   A CG2    1 
ATOM   5892 N N      . LYS   F 1 172 ? 238.790 256.580 227.369 1.00 46.04  ? 184 LYS   A N      1 
ATOM   5893 C CA     . LYS   F 1 172 ? 239.116 256.025 226.067 1.00 48.40  ? 184 LYS   A CA     1 
ATOM   5894 C C      . LYS   F 1 172 ? 237.885 255.378 225.437 1.00 45.07  ? 184 LYS   A C      1 
ATOM   5895 O O      . LYS   F 1 172 ? 236.927 255.004 226.116 1.00 48.59  ? 184 LYS   A O      1 
ATOM   5896 C CB     . LYS   F 1 172 ? 240.268 255.028 226.187 1.00 48.00  ? 184 LYS   A CB     1 
ATOM   5897 C CG     . LYS   F 1 172 ? 239.861 253.620 226.543 1.00 47.85  ? 184 LYS   A CG     1 
ATOM   5898 C CD     . LYS   F 1 172 ? 241.027 252.878 227.170 1.00 49.29  ? 184 LYS   A CD     1 
ATOM   5899 C CE     . LYS   F 1 172 ? 242.348 253.349 226.591 1.00 46.38  ? 184 LYS   A CE     1 
ATOM   5900 N NZ     . LYS   F 1 172 ? 243.508 252.790 227.329 1.00 43.96  ? 184 LYS   A NZ     1 
ATOM   5901 N N      . GLY   F 1 173 ? 237.925 255.244 224.112 1.00 43.46  ? 185 GLY   A N      1 
ATOM   5902 C CA     . GLY   F 1 173 ? 236.763 254.896 223.330 1.00 44.19  ? 185 GLY   A CA     1 
ATOM   5903 C C      . GLY   F 1 173 ? 236.716 253.426 222.945 1.00 46.79  ? 185 GLY   A C      1 
ATOM   5904 O O      . GLY   F 1 173 ? 237.632 252.647 223.200 1.00 50.51  ? 185 GLY   A O      1 
ATOM   5905 N N      . VAL   F 1 174 ? 235.602 253.061 222.309 1.00 45.50  ? 186 VAL   A N      1 
ATOM   5906 C CA     . VAL   F 1 174 ? 235.382 251.670 221.931 1.00 46.18  ? 186 VAL   A CA     1 
ATOM   5907 C C      . VAL   F 1 174 ? 236.435 251.212 220.933 1.00 46.13  ? 186 VAL   A C      1 
ATOM   5908 O O      . VAL   F 1 174 ? 236.962 250.098 221.034 1.00 49.43  ? 186 VAL   A O      1 
ATOM   5909 C CB     . VAL   F 1 174 ? 233.960 251.490 221.373 1.00 43.24  ? 186 VAL   A CB     1 
ATOM   5910 C CG1    . VAL   F 1 174 ? 233.720 250.040 221.000 1.00 43.49  ? 186 VAL   A CG1    1 
ATOM   5911 C CG2    . VAL   F 1 174 ? 232.933 251.965 222.383 1.00 45.78  ? 186 VAL   A CG2    1 
ATOM   5912 N N      . GLY   F 1 175 ? 236.757 252.057 219.954 1.00 43.88  ? 187 GLY   A N      1 
ATOM   5913 C CA     . GLY   F 1 175 ? 237.746 251.677 218.964 1.00 43.04  ? 187 GLY   A CA     1 
ATOM   5914 C C      . GLY   F 1 175 ? 239.104 251.383 219.565 1.00 47.02  ? 187 GLY   A C      1 
ATOM   5915 O O      . GLY   F 1 175 ? 239.782 250.441 219.147 1.00 52.54  ? 187 GLY   A O      1 
ATOM   5916 N N      . THR   F 1 176 ? 239.526 252.185 220.544 1.00 45.34  ? 188 THR   A N      1 
ATOM   5917 C CA     . THR   F 1 176 ? 240.794 251.919 221.213 1.00 46.58  ? 188 THR   A CA     1 
ATOM   5918 C C      . THR   F 1 176 ? 240.733 250.619 222.002 1.00 48.85  ? 188 THR   A C      1 
ATOM   5919 O O      . THR   F 1 176 ? 241.689 249.835 221.996 1.00 51.80  ? 188 THR   A O      1 
ATOM   5920 C CB     . THR   F 1 176 ? 241.162 253.084 222.130 1.00 45.97  ? 188 THR   A CB     1 
ATOM   5921 O OG1    . THR   F 1 176 ? 240.502 252.927 223.391 1.00 51.36  ? 188 THR   A OG1    1 
ATOM   5922 C CG2    . THR   F 1 176 ? 240.735 254.397 221.508 1.00 46.93  ? 188 THR   A CG2    1 
ATOM   5923 N N      . MET   F 1 177 ? 239.618 250.376 222.695 1.00 46.54  ? 189 MET   A N      1 
ATOM   5924 C CA     . MET   F 1 177 ? 239.471 249.129 223.437 1.00 47.28  ? 189 MET   A CA     1 
ATOM   5925 C C      . MET   F 1 177 ? 239.479 247.927 222.504 1.00 50.85  ? 189 MET   A C      1 
ATOM   5926 O O      . MET   F 1 177 ? 240.110 246.907 222.801 1.00 54.28  ? 189 MET   A O      1 
ATOM   5927 C CB     . MET   F 1 177 ? 238.186 249.153 224.263 1.00 49.01  ? 189 MET   A CB     1 
ATOM   5928 C CG     . MET   F 1 177 ? 238.064 250.340 225.195 1.00 48.27  ? 189 MET   A CG     1 
ATOM   5929 S SD     . MET   F 1 177 ? 239.004 250.087 226.707 1.00 57.12  ? 189 MET   A SD     1 
ATOM   5930 C CE     . MET   F 1 177 ? 238.987 248.301 226.806 1.00 53.60  ? 189 MET   A CE     1 
ATOM   5931 N N      . VAL   F 1 178 ? 238.777 248.023 221.375 1.00 48.98  ? 190 VAL   A N      1 
ATOM   5932 C CA     . VAL   F 1 178 ? 238.766 246.922 220.417 1.00 49.11  ? 190 VAL   A CA     1 
ATOM   5933 C C      . VAL   F 1 178 ? 240.161 246.695 219.852 1.00 49.11  ? 190 VAL   A C      1 
ATOM   5934 O O      . VAL   F 1 178 ? 240.621 245.553 219.738 1.00 50.47  ? 190 VAL   A O      1 
ATOM   5935 C CB     . VAL   F 1 178 ? 237.738 247.190 219.303 1.00 48.09  ? 190 VAL   A CB     1 
ATOM   5936 C CG1    . VAL   F 1 178 ? 237.881 246.164 218.195 1.00 49.75  ? 190 VAL   A CG1    1 
ATOM   5937 C CG2    . VAL   F 1 178 ? 236.330 247.168 219.870 1.00 46.47  ? 190 VAL   A CG2    1 
ATOM   5938 N N      . MET   F 1 179 ? 240.859 247.776 219.497 1.00 49.64  ? 191 MET   A N      1 
ATOM   5939 C CA     . MET   F 1 179 ? 242.198 247.632 218.934 1.00 50.36  ? 191 MET   A CA     1 
ATOM   5940 C C      . MET   F 1 179 ? 243.141 246.959 219.922 1.00 49.89  ? 191 MET   A C      1 
ATOM   5941 O O      . MET   F 1 179 ? 243.995 246.158 219.526 1.00 49.72  ? 191 MET   A O      1 
ATOM   5942 C CB     . MET   F 1 179 ? 242.746 248.995 218.511 1.00 52.21  ? 191 MET   A CB     1 
ATOM   5943 C CG     . MET   F 1 179 ? 244.263 249.063 218.481 1.00 57.39  ? 191 MET   A CG     1 
ATOM   5944 S SD     . MET   F 1 179 ? 244.904 250.673 217.989 1.00 64.87  ? 191 MET   A SD     1 
ATOM   5945 C CE     . MET   F 1 179 ? 243.802 251.071 216.641 1.00 50.45  ? 191 MET   A CE     1 
ATOM   5946 N N      . GLU   F 1 180 ? 243.010 247.279 221.210 1.00 51.01  ? 192 GLU   A N      1 
ATOM   5947 C CA     . GLU   F 1 180 ? 243.832 246.621 222.219 1.00 49.26  ? 192 GLU   A CA     1 
ATOM   5948 C C      . GLU   F 1 180 ? 243.551 245.125 222.257 1.00 48.89  ? 192 GLU   A C      1 
ATOM   5949 O O      . GLU   F 1 180 ? 244.476 244.307 222.305 1.00 49.28  ? 192 GLU   A O      1 
ATOM   5950 C CB     . GLU   F 1 180 ? 243.582 247.251 223.587 1.00 48.17  ? 192 GLU   A CB     1 
ATOM   5951 C CG     . GLU   F 1 180 ? 244.002 248.700 223.685 1.00 49.46  ? 192 GLU   A CG     1 
ATOM   5952 C CD     . GLU   F 1 180 ? 244.016 249.198 225.111 1.00 60.06  ? 192 GLU   A CD     1 
ATOM   5953 O OE1    . GLU   F 1 180 ? 242.963 249.127 225.777 1.00 61.64  ? 192 GLU   A OE1    1 
ATOM   5954 O OE2    . GLU   F 1 180 ? 245.080 249.664 225.567 1.00 72.19  ? 192 GLU   A OE2    1 
ATOM   5955 N N      . LEU   F 1 181 ? 242.270 244.750 222.239 1.00 49.62  ? 193 LEU   A N      1 
ATOM   5956 C CA     . LEU   F 1 181 ? 241.912 243.336 222.224 1.00 50.91  ? 193 LEU   A CA     1 
ATOM   5957 C C      . LEU   F 1 181 ? 242.404 242.658 220.955 1.00 50.22  ? 193 LEU   A C      1 
ATOM   5958 O O      . LEU   F 1 181 ? 242.910 241.531 221.000 1.00 52.28  ? 193 LEU   A O      1 
ATOM   5959 C CB     . LEU   F 1 181 ? 240.398 243.176 222.361 1.00 53.09  ? 193 LEU   A CB     1 
ATOM   5960 C CG     . LEU   F 1 181 ? 239.734 243.896 223.531 1.00 52.50  ? 193 LEU   A CG     1 
ATOM   5961 C CD1    . LEU   F 1 181 ? 238.288 243.465 223.668 1.00 50.99  ? 193 LEU   A CD1    1 
ATOM   5962 C CD2    . LEU   F 1 181 ? 240.490 243.603 224.802 1.00 50.98  ? 193 LEU   A CD2    1 
ATOM   5963 N N      . ILE   F 1 182 ? 242.265 243.329 219.811 1.00 49.74  ? 194 ILE   A N      1 
ATOM   5964 C CA     . ILE   F 1 182 ? 242.670 242.729 218.544 1.00 49.86  ? 194 ILE   A CA     1 
ATOM   5965 C C      . ILE   F 1 182 ? 244.169 242.456 218.536 1.00 48.32  ? 194 ILE   A C      1 
ATOM   5966 O O      . ILE   F 1 182 ? 244.625 241.440 217.999 1.00 48.51  ? 194 ILE   A O      1 
ATOM   5967 C CB     . ILE   F 1 182 ? 242.244 243.624 217.367 1.00 53.00  ? 194 ILE   A CB     1 
ATOM   5968 C CG1    . ILE   F 1 182 ? 240.755 243.436 217.080 1.00 49.34  ? 194 ILE   A CG1    1 
ATOM   5969 C CG2    . ILE   F 1 182 ? 243.064 243.304 216.131 1.00 58.59  ? 194 ILE   A CG2    1 
ATOM   5970 C CD1    . ILE   F 1 182 ? 240.306 244.048 215.779 1.00 55.28  ? 194 ILE   A CD1    1 
ATOM   5971 N N      . ARG   F 1 183 ? 244.960 243.354 219.128 1.00 49.89  ? 195 ARG   A N      1 
ATOM   5972 C CA     . ARG   F 1 183 ? 246.390 243.092 219.255 1.00 51.09  ? 195 ARG   A CA     1 
ATOM   5973 C C      . ARG   F 1 183 ? 246.646 241.856 220.104 1.00 53.96  ? 195 ARG   A C      1 
ATOM   5974 O O      . ARG   F 1 183 ? 247.529 241.050 219.792 1.00 57.50  ? 195 ARG   A O      1 
ATOM   5975 C CB     . ARG   F 1 183 ? 247.108 244.302 219.851 1.00 49.01  ? 195 ARG   A CB     1 
ATOM   5976 C CG     . ARG   F 1 183 ? 247.098 245.534 218.975 1.00 55.59  ? 195 ARG   A CG     1 
ATOM   5977 C CD     . ARG   F 1 183 ? 247.607 246.741 219.739 1.00 60.19  ? 195 ARG   A CD     1 
ATOM   5978 N NE     . ARG   F 1 183 ? 247.833 247.884 218.864 1.00 66.99  ? 195 ARG   A NE     1 
ATOM   5979 C CZ     . ARG   F 1 183 ? 248.969 248.124 218.226 1.00 68.31  ? 195 ARG   A CZ     1 
ATOM   5980 N NH1    . ARG   F 1 183 ? 250.012 247.320 218.345 1.00 67.80  ? 195 ARG   A NH1    1 
ATOM   5981 N NH2    . ARG   F 1 183 ? 249.062 249.199 217.449 1.00 70.06  ? 195 ARG   A NH2    1 
ATOM   5982 N N      . MET   F 1 184 ? 245.888 241.693 221.189 1.00 53.11  ? 196 MET   A N      1 
ATOM   5983 C CA     . MET   F 1 184 ? 246.018 240.491 222.005 1.00 51.77  ? 196 MET   A CA     1 
ATOM   5984 C C      . MET   F 1 184 ? 245.690 239.242 221.197 1.00 55.15  ? 196 MET   A C      1 
ATOM   5985 O O      . MET   F 1 184 ? 246.399 238.234 221.282 1.00 58.14  ? 196 MET   A O      1 
ATOM   5986 C CB     . MET   F 1 184 ? 245.110 240.589 223.230 1.00 52.51  ? 196 MET   A CB     1 
ATOM   5987 C CG     . MET   F 1 184 ? 245.562 241.601 224.264 1.00 51.59  ? 196 MET   A CG     1 
ATOM   5988 S SD     . MET   F 1 184 ? 245.321 241.019 225.950 1.00 64.72  ? 196 MET   A SD     1 
ATOM   5989 C CE     . MET   F 1 184 ? 246.166 242.299 226.867 1.00 50.90  ? 196 MET   A CE     1 
ATOM   5990 N N      . ILE   F 1 185 ? 244.616 239.291 220.407 1.00 54.31  ? 197 ILE   A N      1 
ATOM   5991 C CA     . ILE   F 1 185 ? 244.245 238.142 219.587 1.00 53.18  ? 197 ILE   A CA     1 
ATOM   5992 C C      . ILE   F 1 185 ? 245.321 237.858 218.548 1.00 55.25  ? 197 ILE   A C      1 
ATOM   5993 O O      . ILE   F 1 185 ? 245.687 236.701 218.313 1.00 61.93  ? 197 ILE   A O      1 
ATOM   5994 C CB     . ILE   F 1 185 ? 242.871 238.373 218.931 1.00 55.78  ? 197 ILE   A CB     1 
ATOM   5995 C CG1    . ILE   F 1 185 ? 241.812 238.653 219.997 1.00 52.91  ? 197 ILE   A CG1    1 
ATOM   5996 C CG2    . ILE   F 1 185 ? 242.472 237.171 218.095 1.00 63.01  ? 197 ILE   A CG2    1 
ATOM   5997 C CD1    . ILE   F 1 185 ? 242.023 237.890 221.279 1.00 58.01  ? 197 ILE   A CD1    1 
ATOM   5998 N N      . LYS   F 1 186 ? 245.845 238.906 217.908 1.00 53.51  ? 198 LYS   A N      1 
ATOM   5999 C CA     . LYS   F 1 186 ? 246.893 238.707 216.912 1.00 56.13  ? 198 LYS   A CA     1 
ATOM   6000 C C      . LYS   F 1 186 ? 248.141 238.098 217.536 1.00 58.29  ? 198 LYS   A C      1 
ATOM   6001 O O      . LYS   F 1 186 ? 248.768 237.210 216.947 1.00 64.46  ? 198 LYS   A O      1 
ATOM   6002 C CB     . LYS   F 1 186 ? 247.229 240.029 216.225 1.00 57.49  ? 198 LYS   A CB     1 
ATOM   6003 C CG     . LYS   F 1 186 ? 246.059 240.670 215.509 1.00 58.06  ? 198 LYS   A CG     1 
ATOM   6004 C CD     . LYS   F 1 186 ? 245.858 240.054 214.139 1.00 57.36  ? 198 LYS   A CD     1 
ATOM   6005 C CE     . LYS   F 1 186 ? 245.658 241.126 213.086 1.00 64.93  ? 198 LYS   A CE     1 
ATOM   6006 N NZ     . LYS   F 1 186 ? 246.765 242.120 213.100 1.00 65.86  ? 198 LYS   A NZ     1 
ATOM   6007 N N      . ARG   F 1 187 ? 248.523 238.566 218.724 1.00 54.15  ? 199 ARG   A N      1 
ATOM   6008 C CA     . ARG   F 1 187 ? 249.669 237.974 219.405 1.00 59.31  ? 199 ARG   A CA     1 
ATOM   6009 C C      . ARG   F 1 187 ? 249.402 236.519 219.765 1.00 63.47  ? 199 ARG   A C      1 
ATOM   6010 O O      . ARG   F 1 187 ? 250.289 235.668 219.633 1.00 69.01  ? 199 ARG   A O      1 
ATOM   6011 C CB     . ARG   F 1 187 ? 250.015 238.780 220.653 1.00 60.97  ? 199 ARG   A CB     1 
ATOM   6012 C CG     . ARG   F 1 187 ? 250.631 240.131 220.364 1.00 63.56  ? 199 ARG   A CG     1 
ATOM   6013 C CD     . ARG   F 1 187 ? 252.084 240.163 220.795 1.00 65.97  ? 199 ARG   A CD     1 
ATOM   6014 N NE     . ARG   F 1 187 ? 252.230 240.548 222.192 1.00 69.76  ? 199 ARG   A NE     1 
ATOM   6015 C CZ     . ARG   F 1 187 ? 251.827 241.705 222.697 1.00 72.99  ? 199 ARG   A CZ     1 
ATOM   6016 N NH1    . ARG   F 1 187 ? 251.253 242.626 221.942 1.00 71.49  ? 199 ARG   A NH1    1 
ATOM   6017 N NH2    . ARG   F 1 187 ? 252.006 241.944 223.993 1.00 71.13  ? 199 ARG   A NH2    1 
ATOM   6018 N N      . GLY   F 1 188 ? 248.188 236.213 220.222 1.00 60.47  ? 200 GLY   A N      1 
ATOM   6019 C CA     . GLY   F 1 188 ? 247.872 234.841 220.581 1.00 60.12  ? 200 GLY   A CA     1 
ATOM   6020 C C      . GLY   F 1 188 ? 247.879 233.908 219.386 1.00 62.64  ? 200 GLY   A C      1 
ATOM   6021 O O      . GLY   F 1 188 ? 248.352 232.773 219.477 1.00 73.67  ? 200 GLY   A O      1 
ATOM   6022 N N      . ILE   F 1 189 ? 247.353 234.370 218.252 1.00 60.08  ? 201 ILE   A N      1 
ATOM   6023 C CA     . ILE   F 1 189 ? 247.325 233.538 217.054 1.00 63.69  ? 201 ILE   A CA     1 
ATOM   6024 C C      . ILE   F 1 189 ? 248.740 233.259 216.565 1.00 66.93  ? 201 ILE   A C      1 
ATOM   6025 O O      . ILE   F 1 189 ? 249.071 232.133 216.179 1.00 71.21  ? 201 ILE   A O      1 
ATOM   6026 C CB     . ILE   F 1 189 ? 246.470 234.202 215.961 1.00 60.55  ? 201 ILE   A CB     1 
ATOM   6027 C CG1    . ILE   F 1 189 ? 244.984 234.000 216.258 1.00 60.90  ? 201 ILE   A CG1    1 
ATOM   6028 C CG2    . ILE   F 1 189 ? 246.826 233.646 214.596 1.00 63.02  ? 201 ILE   A CG2    1 
ATOM   6029 C CD1    . ILE   F 1 189 ? 244.074 234.834 215.392 1.00 66.41  ? 201 ILE   A CD1    1 
ATOM   6030 N N      . ASN   F 1 190 ? 249.596 234.282 216.567 1.00 65.61  ? 202 ASN   A N      1 
ATOM   6031 C CA     . ASN   F 1 190 ? 250.961 234.101 216.084 1.00 67.29  ? 202 ASN   A CA     1 
ATOM   6032 C C      . ASN   F 1 190 ? 251.769 233.199 217.010 1.00 73.41  ? 202 ASN   A C      1 
ATOM   6033 O O      . ASN   F 1 190 ? 252.485 232.306 216.544 1.00 80.78  ? 202 ASN   A O      1 
ATOM   6034 C CB     . ASN   F 1 190 ? 251.644 235.457 215.931 1.00 69.14  ? 202 ASN   A CB     1 
ATOM   6035 C CG     . ASN   F 1 190 ? 250.948 236.344 214.925 1.00 78.96  ? 202 ASN   A CG     1 
ATOM   6036 O OD1    . ASN   F 1 190 ? 249.905 235.984 214.381 1.00 79.28  ? 202 ASN   A OD1    1 
ATOM   6037 N ND2    . ASN   F 1 190 ? 251.521 237.514 214.670 1.00 83.96  ? 202 ASN   A ND2    1 
ATOM   6038 N N      . ASP   F 1 191 ? 251.667 233.411 218.318 1.00 70.15  ? 203 ASP   A N      1 
ATOM   6039 C CA     . ASP   F 1 191 ? 252.455 232.680 219.306 1.00 73.54  ? 203 ASP   A CA     1 
ATOM   6040 C C      . ASP   F 1 191 ? 251.566 231.635 219.966 1.00 77.78  ? 203 ASP   A C      1 
ATOM   6041 O O      . ASP   F 1 191 ? 250.595 231.978 220.647 1.00 81.31  ? 203 ASP   A O      1 
ATOM   6042 C CB     . ASP   F 1 191 ? 253.042 233.633 220.343 1.00 77.24  ? 203 ASP   A CB     1 
ATOM   6043 C CG     . ASP   F 1 191 ? 253.997 232.942 221.293 1.00 88.34  ? 203 ASP   A CG     1 
ATOM   6044 O OD1    . ASP   F 1 191 ? 254.301 231.752 221.070 1.00 91.20  ? 203 ASP   A OD1    1 
ATOM   6045 O OD2    . ASP   F 1 191 ? 254.443 233.588 222.264 1.00 94.15  ? 203 ASP   A OD2    1 
ATOM   6046 N N      . ARG   F 1 192 ? 251.904 230.359 219.768 1.00 77.43  ? 204 ARG   A N      1 
ATOM   6047 C CA     . ARG   F 1 192 ? 251.109 229.291 220.364 1.00 77.63  ? 204 ARG   A CA     1 
ATOM   6048 C C      . ARG   F 1 192 ? 251.268 229.246 221.878 1.00 78.23  ? 204 ARG   A C      1 
ATOM   6049 O O      . ARG   F 1 192 ? 250.346 228.819 222.582 1.00 82.62  ? 204 ARG   A O      1 
ATOM   6050 C CB     . ARG   F 1 192 ? 251.485 227.944 219.748 1.00 91.41  ? 204 ARG   A CB     1 
ATOM   6051 C CG     . ARG   F 1 192 ? 251.126 226.748 220.614 1.00 99.34  ? 204 ARG   A CG     1 
ATOM   6052 C CD     . ARG   F 1 192 ? 252.091 225.595 220.396 1.00 109.35 ? 204 ARG   A CD     1 
ATOM   6053 N NE     . ARG   F 1 192 ? 252.671 225.615 219.059 1.00 118.46 ? 204 ARG   A NE     1 
ATOM   6054 C CZ     . ARG   F 1 192 ? 253.919 225.268 218.778 1.00 121.76 ? 204 ARG   A CZ     1 
ATOM   6055 N NH1    . ARG   F 1 192 ? 254.753 224.860 219.721 1.00 123.38 ? 204 ARG   A NH1    1 
ATOM   6056 N NH2    . ARG   F 1 192 ? 254.342 225.329 217.518 1.00 120.60 ? 204 ARG   A NH2    1 
ATOM   6057 N N      . ASN   F 1 193 ? 252.419 229.674 222.398 1.00 75.12  ? 205 ASN   A N      1 
ATOM   6058 C CA     . ASN   F 1 193 ? 252.605 229.710 223.843 1.00 75.52  ? 205 ASN   A CA     1 
ATOM   6059 C C      . ASN   F 1 193 ? 251.809 230.820 224.512 1.00 76.46  ? 205 ASN   A C      1 
ATOM   6060 O O      . ASN   F 1 193 ? 251.716 230.834 225.743 1.00 77.73  ? 205 ASN   A O      1 
ATOM   6061 C CB     . ASN   F 1 193 ? 254.085 229.863 224.186 1.00 79.44  ? 205 ASN   A CB     1 
ATOM   6062 C CG     . ASN   F 1 193 ? 254.446 229.190 225.492 1.00 83.36  ? 205 ASN   A CG     1 
ATOM   6063 O OD1    . ASN   F 1 193 ? 254.232 227.991 225.665 1.00 82.93  ? 205 ASN   A OD1    1 
ATOM   6064 N ND2    . ASN   F 1 193 ? 254.993 229.962 226.424 1.00 86.07  ? 205 ASN   A ND2    1 
ATOM   6065 N N      . PHE   F 1 194 ? 251.245 231.743 223.742 1.00 75.05  ? 206 PHE   A N      1 
ATOM   6066 C CA     . PHE   F 1 194 ? 250.355 232.746 224.302 1.00 70.28  ? 206 PHE   A CA     1 
ATOM   6067 C C      . PHE   F 1 194 ? 249.135 232.077 224.924 1.00 74.15  ? 206 PHE   A C      1 
ATOM   6068 O O      . PHE   F 1 194 ? 248.647 231.052 224.442 1.00 77.51  ? 206 PHE   A O      1 
ATOM   6069 C CB     . PHE   F 1 194 ? 249.926 233.733 223.217 1.00 71.76  ? 206 PHE   A CB     1 
ATOM   6070 C CG     . PHE   F 1 194 ? 249.896 235.162 223.670 1.00 64.06  ? 206 PHE   A CG     1 
ATOM   6071 C CD1    . PHE   F 1 194 ? 251.047 235.788 224.107 1.00 65.50  ? 206 PHE   A CD1    1 
ATOM   6072 C CD2    . PHE   F 1 194 ? 248.721 235.889 223.627 1.00 60.46  ? 206 PHE   A CD2    1 
ATOM   6073 C CE1    . PHE   F 1 194 ? 251.021 237.104 224.518 1.00 61.23  ? 206 PHE   A CE1    1 
ATOM   6074 C CE2    . PHE   F 1 194 ? 248.691 237.206 224.033 1.00 59.44  ? 206 PHE   A CE2    1 
ATOM   6075 C CZ     . PHE   F 1 194 ? 249.842 237.814 224.479 1.00 59.95  ? 206 PHE   A CZ     1 
ATOM   6076 N N      . TRP   F 1 195 ? 248.648 232.666 226.013 1.00 69.59  ? 207 TRP   A N      1 
ATOM   6077 C CA     . TRP   F 1 195 ? 247.508 232.139 226.757 1.00 68.47  ? 207 TRP   A CA     1 
ATOM   6078 C C      . TRP   F 1 195 ? 247.865 230.888 227.550 1.00 75.35  ? 207 TRP   A C      1 
ATOM   6079 O O      . TRP   F 1 195 ? 246.977 230.213 228.078 1.00 81.63  ? 207 TRP   A O      1 
ATOM   6080 C CB     . TRP   F 1 195 ? 246.329 231.830 225.829 1.00 69.10  ? 207 TRP   A CB     1 
ATOM   6081 C CG     . TRP   F 1 195 ? 245.938 232.946 224.922 1.00 66.62  ? 207 TRP   A CG     1 
ATOM   6082 C CD1    . TRP   F 1 195 ? 245.995 232.951 223.560 1.00 65.75  ? 207 TRP   A CD1    1 
ATOM   6083 C CD2    . TRP   F 1 195 ? 245.410 234.218 225.306 1.00 64.38  ? 207 TRP   A CD2    1 
ATOM   6084 N NE1    . TRP   F 1 195 ? 245.541 234.150 223.072 1.00 63.98  ? 207 TRP   A NE1    1 
ATOM   6085 C CE2    . TRP   F 1 195 ? 245.176 234.946 224.125 1.00 63.90  ? 207 TRP   A CE2    1 
ATOM   6086 C CE3    . TRP   F 1 195 ? 245.116 234.813 226.534 1.00 63.59  ? 207 TRP   A CE3    1 
ATOM   6087 C CZ2    . TRP   F 1 195 ? 244.664 236.237 224.137 1.00 64.09  ? 207 TRP   A CZ2    1 
ATOM   6088 C CZ3    . TRP   F 1 195 ? 244.609 236.093 226.543 1.00 62.59  ? 207 TRP   A CZ3    1 
ATOM   6089 C CH2    . TRP   F 1 195 ? 244.387 236.792 225.354 1.00 63.68  ? 207 TRP   A CH2    1 
ATOM   6090 N N      . ARG   F 1 196 ? 249.151 230.561 227.647 1.00 73.91  ? 208 ARG   A N      1 
ATOM   6091 C CA     . ARG   F 1 196 ? 249.579 229.344 228.320 1.00 72.23  ? 208 ARG   A CA     1 
ATOM   6092 C C      . ARG   F 1 196 ? 250.776 229.667 229.197 1.00 71.93  ? 208 ARG   A C      1 
ATOM   6093 O O      . ARG   F 1 196 ? 251.586 230.534 228.861 1.00 75.84  ? 208 ARG   A O      1 
ATOM   6094 C CB     . ARG   F 1 196 ? 249.930 228.238 227.319 1.00 71.11  ? 208 ARG   A CB     1 
ATOM   6095 C CG     . ARG   F 1 196 ? 248.882 228.037 226.239 1.00 75.39  ? 208 ARG   A CG     1 
ATOM   6096 C CD     . ARG   F 1 196 ? 249.167 226.856 225.310 1.00 77.15  ? 208 ARG   A CD     1 
ATOM   6097 N NE     . ARG   F 1 196 ? 249.744 225.696 225.981 1.00 82.03  ? 208 ARG   A NE     1 
ATOM   6098 C CZ     . ARG   F 1 196 ? 251.021 225.574 226.314 1.00 88.69  ? 208 ARG   A CZ     1 
ATOM   6099 N NH1    . ARG   F 1 196 ? 251.906 226.512 226.019 1.00 86.29  ? 208 ARG   A NH1    1 
ATOM   6100 N NH2    . ARG   F 1 196 ? 251.424 224.475 226.946 1.00 90.62  ? 208 ARG   A NH2    1 
ATOM   6101 N N      . GLY   F 1 197 ? 250.877 228.969 230.317 1.00 70.38  ? 209 GLY   A N      1 
ATOM   6102 C CA     . GLY   F 1 197 ? 251.928 229.235 231.271 1.00 73.22  ? 209 GLY   A CA     1 
ATOM   6103 C C      . GLY   F 1 197 ? 251.510 230.263 232.298 1.00 72.69  ? 209 GLY   A C      1 
ATOM   6104 O O      . GLY   F 1 197 ? 250.368 230.729 232.346 1.00 75.31  ? 209 GLY   A O      1 
ATOM   6105 N N      . GLU   F 1 198 ? 252.472 230.621 233.147 1.00 72.86  ? 210 GLU   A N      1 
ATOM   6106 C CA     . GLU   F 1 198 ? 252.204 231.604 234.191 1.00 74.28  ? 210 GLU   A CA     1 
ATOM   6107 C C      . GLU   F 1 198 ? 251.882 232.968 233.594 1.00 76.42  ? 210 GLU   A C      1 
ATOM   6108 O O      . GLU   F 1 198 ? 250.967 233.660 234.053 1.00 79.10  ? 210 GLU   A O      1 
ATOM   6109 C CB     . GLU   F 1 198 ? 253.394 231.700 235.141 1.00 77.43  ? 210 GLU   A CB     1 
ATOM   6110 C CG     . GLU   F 1 198 ? 252.992 231.893 236.585 1.00 83.79  ? 210 GLU   A CG     1 
ATOM   6111 C CD     . GLU   F 1 198 ? 252.725 233.344 236.912 1.00 90.10  ? 210 GLU   A CD     1 
ATOM   6112 O OE1    . GLU   F 1 198 ? 253.052 234.210 236.075 1.00 88.86  ? 210 GLU   A OE1    1 
ATOM   6113 O OE2    . GLU   F 1 198 ? 252.186 233.619 238.003 1.00 94.21  ? 210 GLU   A OE2    1 
ATOM   6114 N N      . ASN   F 1 199 ? 252.637 233.379 232.573 1.00 76.44  ? 211 ASN   A N      1 
ATOM   6115 C CA     . ASN   F 1 199 ? 252.375 234.670 231.947 1.00 70.91  ? 211 ASN   A CA     1 
ATOM   6116 C C      . ASN   F 1 199 ? 251.065 234.665 231.172 1.00 67.64  ? 211 ASN   A C      1 
ATOM   6117 O O      . ASN   F 1 199 ? 250.398 235.700 231.082 1.00 67.76  ? 211 ASN   A O      1 
ATOM   6118 C CB     . ASN   F 1 199 ? 253.533 235.059 231.032 1.00 70.04  ? 211 ASN   A CB     1 
ATOM   6119 C CG     . ASN   F 1 199 ? 254.391 236.156 231.623 1.00 79.64  ? 211 ASN   A CG     1 
ATOM   6120 O OD1    . ASN   F 1 199 ? 253.924 236.954 232.436 1.00 71.89  ? 211 ASN   A OD1    1 
ATOM   6121 N ND2    . ASN   F 1 199 ? 255.653 236.205 231.216 1.00 93.73  ? 211 ASN   A ND2    1 
ATOM   6122 N N      . GLY   F 1 200 ? 250.682 233.520 230.607 1.00 68.17  ? 212 GLY   A N      1 
ATOM   6123 C CA     . GLY   F 1 200 ? 249.384 233.435 229.961 1.00 69.69  ? 212 GLY   A CA     1 
ATOM   6124 C C      . GLY   F 1 200 ? 248.246 233.707 230.925 1.00 67.61  ? 212 GLY   A C      1 
ATOM   6125 O O      . GLY   F 1 200 ? 247.254 234.345 230.566 1.00 68.61  ? 212 GLY   A O      1 
ATOM   6126 N N      . ARG   F 1 201 ? 248.375 233.227 232.163 1.00 64.18  ? 213 ARG   A N      1 
ATOM   6127 C CA     . ARG   F 1 201 ? 247.363 233.515 233.173 1.00 68.09  ? 213 ARG   A CA     1 
ATOM   6128 C C      . ARG   F 1 201 ? 247.269 235.010 233.443 1.00 67.10  ? 213 ARG   A C      1 
ATOM   6129 O O      . ARG   F 1 201 ? 246.169 235.560 233.562 1.00 69.55  ? 213 ARG   A O      1 
ATOM   6130 C CB     . ARG   F 1 201 ? 247.678 232.753 234.459 1.00 74.35  ? 213 ARG   A CB     1 
ATOM   6131 C CG     . ARG   F 1 201 ? 246.458 232.441 235.310 1.00 79.36  ? 213 ARG   A CG     1 
ATOM   6132 C CD     . ARG   F 1 201 ? 246.761 231.455 236.440 1.00 85.83  ? 213 ARG   A CD     1 
ATOM   6133 N NE     . ARG   F 1 201 ? 247.891 230.568 236.183 1.00 85.45  ? 213 ARG   A NE     1 
ATOM   6134 C CZ     . ARG   F 1 201 ? 248.064 229.855 235.078 1.00 83.83  ? 213 ARG   A CZ     1 
ATOM   6135 N NH1    . ARG   F 1 201 ? 247.174 229.866 234.099 1.00 81.04  ? 213 ARG   A NH1    1 
ATOM   6136 N NH2    . ARG   F 1 201 ? 249.152 229.100 234.957 1.00 83.95  ? 213 ARG   A NH2    1 
ATOM   6137 N N      . ARG   F 1 202 ? 248.415 235.685 233.545 1.00 65.14  ? 214 ARG   A N      1 
ATOM   6138 C CA     . ARG   F 1 202 ? 248.408 237.133 233.721 1.00 64.32  ? 214 ARG   A CA     1 
ATOM   6139 C C      . ARG   F 1 202 ? 247.784 237.827 232.518 1.00 61.71  ? 214 ARG   A C      1 
ATOM   6140 O O      . ARG   F 1 202 ? 247.023 238.790 232.671 1.00 59.56  ? 214 ARG   A O      1 
ATOM   6141 C CB     . ARG   F 1 202 ? 249.830 237.637 233.955 1.00 69.32  ? 214 ARG   A CB     1 
ATOM   6142 C CG     . ARG   F 1 202 ? 249.905 239.064 234.454 1.00 77.34  ? 214 ARG   A CG     1 
ATOM   6143 C CD     . ARG   F 1 202 ? 250.051 239.099 235.962 1.00 79.67  ? 214 ARG   A CD     1 
ATOM   6144 N NE     . ARG   F 1 202 ? 250.905 238.021 236.445 1.00 83.07  ? 214 ARG   A NE     1 
ATOM   6145 C CZ     . ARG   F 1 202 ? 252.176 237.862 236.103 1.00 88.63  ? 214 ARG   A CZ     1 
ATOM   6146 N NH1    . ARG   F 1 202 ? 252.779 238.698 235.274 1.00 91.12  ? 214 ARG   A NH1    1 
ATOM   6147 N NH2    . ARG   F 1 202 ? 252.859 236.839 236.606 1.00 95.00  ? 214 ARG   A NH2    1 
ATOM   6148 N N      . THR   F 1 203 ? 248.104 237.358 231.311 1.00 63.49  ? 215 THR   A N      1 
ATOM   6149 C CA     . THR   F 1 203 ? 247.481 237.907 230.111 1.00 60.99  ? 215 THR   A CA     1 
ATOM   6150 C C      . THR   F 1 203 ? 245.981 237.647 230.104 1.00 58.99  ? 215 THR   A C      1 
ATOM   6151 O O      . THR   F 1 203 ? 245.196 238.508 229.690 1.00 58.68  ? 215 THR   A O      1 
ATOM   6152 C CB     . THR   F 1 203 ? 248.132 237.315 228.861 1.00 62.61  ? 215 THR   A CB     1 
ATOM   6153 O OG1    . THR   F 1 203 ? 249.556 237.301 229.020 1.00 62.66  ? 215 THR   A OG1    1 
ATOM   6154 C CG2    . THR   F 1 203 ? 247.773 238.135 227.635 1.00 63.17  ? 215 THR   A CG2    1 
ATOM   6155 N N      . ARG   F 1 204 ? 245.563 236.463 230.555 1.00 57.35  ? 216 ARG   A N      1 
ATOM   6156 C CA     . ARG   F 1 204 ? 244.138 236.151 230.578 1.00 58.12  ? 216 ARG   A CA     1 
ATOM   6157 C C      . ARG   F 1 204 ? 243.376 237.104 231.490 1.00 59.24  ? 216 ARG   A C      1 
ATOM   6158 O O      . ARG   F 1 204 ? 242.290 237.576 231.133 1.00 60.63  ? 216 ARG   A O      1 
ATOM   6159 C CB     . ARG   F 1 204 ? 243.920 234.703 231.011 1.00 59.98  ? 216 ARG   A CB     1 
ATOM   6160 C CG     . ARG   F 1 204 ? 242.456 234.290 231.071 1.00 64.36  ? 216 ARG   A CG     1 
ATOM   6161 C CD     . ARG   F 1 204 ? 241.644 234.950 229.971 1.00 59.02  ? 216 ARG   A CD     1 
ATOM   6162 N NE     . ARG   F 1 204 ? 240.254 234.510 229.975 1.00 58.72  ? 216 ARG   A NE     1 
ATOM   6163 C CZ     . ARG   F 1 204 ? 239.552 234.237 228.885 1.00 63.27  ? 216 ARG   A CZ     1 
ATOM   6164 N NH1    . ARG   F 1 204 ? 240.085 234.332 227.678 1.00 64.45  ? 216 ARG   A NH1    1 
ATOM   6165 N NH2    . ARG   F 1 204 ? 238.284 233.860 229.007 1.00 64.29  ? 216 ARG   A NH2    1 
ATOM   6166 N N      . ILE   F 1 205 ? 243.924 237.405 232.668 1.00 56.96  ? 217 ILE   A N      1 
ATOM   6167 C CA     . ILE   F 1 205 ? 243.241 238.325 233.570 1.00 55.45  ? 217 ILE   A CA     1 
ATOM   6168 C C      . ILE   F 1 205 ? 243.185 239.721 232.963 1.00 54.55  ? 217 ILE   A C      1 
ATOM   6169 O O      . ILE   F 1 205 ? 242.190 240.440 233.114 1.00 57.20  ? 217 ILE   A O      1 
ATOM   6170 C CB     . ILE   F 1 205 ? 243.911 238.316 234.959 1.00 58.52  ? 217 ILE   A CB     1 
ATOM   6171 C CG1    . ILE   F 1 205 ? 245.230 239.094 234.957 1.00 64.34  ? 217 ILE   A CG1    1 
ATOM   6172 C CG2    . ILE   F 1 205 ? 244.135 236.891 235.431 1.00 55.93  ? 217 ILE   A CG2    1 
ATOM   6173 C CD1    . ILE   F 1 205 ? 245.078 240.589 235.164 1.00 65.40  ? 217 ILE   A CD1    1 
ATOM   6174 N N      . ALA   F 1 206 ? 244.248 240.127 232.264 1.00 55.52  ? 218 ALA   A N      1 
ATOM   6175 C CA     . ALA   F 1 206 ? 244.223 241.407 231.564 1.00 55.59  ? 218 ALA   A CA     1 
ATOM   6176 C C      . ALA   F 1 206 ? 243.192 241.400 230.445 1.00 56.24  ? 218 ALA   A C      1 
ATOM   6177 O O      . ALA   F 1 206 ? 242.457 242.376 230.260 1.00 57.26  ? 218 ALA   A O      1 
ATOM   6178 C CB     . ALA   F 1 206 ? 245.610 241.731 231.012 1.00 56.15  ? 218 ALA   A CB     1 
ATOM   6179 N N      . TYR   F 1 207 ? 243.126 240.306 229.687 1.00 55.84  ? 219 TYR   A N      1 
ATOM   6180 C CA     . TYR   F 1 207 ? 242.139 240.207 228.620 1.00 55.86  ? 219 TYR   A CA     1 
ATOM   6181 C C      . TYR   F 1 207 ? 240.726 240.264 229.185 1.00 54.93  ? 219 TYR   A C      1 
ATOM   6182 O O      . TYR   F 1 207 ? 239.850 240.933 228.626 1.00 55.00  ? 219 TYR   A O      1 
ATOM   6183 C CB     . TYR   F 1 207 ? 242.377 238.920 227.825 1.00 53.57  ? 219 TYR   A CB     1 
ATOM   6184 C CG     . TYR   F 1 207 ? 241.368 238.611 226.740 1.00 56.69  ? 219 TYR   A CG     1 
ATOM   6185 C CD1    . TYR   F 1 207 ? 240.105 238.129 227.048 1.00 60.92  ? 219 TYR   A CD1    1 
ATOM   6186 C CD2    . TYR   F 1 207 ? 241.690 238.786 225.402 1.00 56.28  ? 219 TYR   A CD2    1 
ATOM   6187 C CE1    . TYR   F 1 207 ? 239.191 237.841 226.058 1.00 58.76  ? 219 TYR   A CE1    1 
ATOM   6188 C CE2    . TYR   F 1 207 ? 240.782 238.500 224.406 1.00 55.90  ? 219 TYR   A CE2    1 
ATOM   6189 C CZ     . TYR   F 1 207 ? 239.535 238.027 224.740 1.00 56.35  ? 219 TYR   A CZ     1 
ATOM   6190 O OH     . TYR   F 1 207 ? 238.628 237.742 223.749 1.00 58.44  ? 219 TYR   A OH     1 
ATOM   6191 N N      . GLU   F 1 208 ? 240.490 239.574 230.302 1.00 51.97  ? 220 GLU   A N      1 
ATOM   6192 C CA     . GLU   F 1 208 ? 239.171 239.593 230.923 1.00 52.59  ? 220 GLU   A CA     1 
ATOM   6193 C C      . GLU   F 1 208 ? 238.815 240.991 231.411 1.00 52.43  ? 220 GLU   A C      1 
ATOM   6194 O O      . GLU   F 1 208 ? 237.710 241.485 231.165 1.00 53.82  ? 220 GLU   A O      1 
ATOM   6195 C CB     . GLU   F 1 208 ? 239.128 238.589 232.075 1.00 56.47  ? 220 GLU   A CB     1 
ATOM   6196 C CG     . GLU   F 1 208 ? 237.800 238.510 232.805 1.00 64.63  ? 220 GLU   A CG     1 
ATOM   6197 C CD     . GLU   F 1 208 ? 237.013 237.273 232.427 1.00 73.44  ? 220 GLU   A CD     1 
ATOM   6198 O OE1    . GLU   F 1 208 ? 237.619 236.334 231.869 1.00 75.79  ? 220 GLU   A OE1    1 
ATOM   6199 O OE2    . GLU   F 1 208 ? 235.795 237.231 232.698 1.00 75.34  ? 220 GLU   A OE2    1 
ATOM   6200 N N      . ARG   F 1 209 ? 239.746 241.646 232.104 1.00 52.27  ? 221 ARG   A N      1 
ATOM   6201 C CA     . ARG   F 1 209 ? 239.451 242.945 232.701 1.00 52.55  ? 221 ARG   A CA     1 
ATOM   6202 C C      . ARG   F 1 209 ? 239.174 243.995 231.634 1.00 51.31  ? 221 ARG   A C      1 
ATOM   6203 O O      . ARG   F 1 209 ? 238.249 244.804 231.770 1.00 50.51  ? 221 ARG   A O      1 
ATOM   6204 C CB     . ARG   F 1 209 ? 240.605 243.384 233.600 1.00 56.00  ? 221 ARG   A CB     1 
ATOM   6205 C CG     . ARG   F 1 209 ? 240.454 242.950 235.044 1.00 60.58  ? 221 ARG   A CG     1 
ATOM   6206 C CD     . ARG   F 1 209 ? 241.639 243.324 235.945 1.00 70.78  ? 221 ARG   A CD     1 
ATOM   6207 N NE     . ARG   F 1 209 ? 241.838 244.760 236.119 1.00 66.21  ? 221 ARG   A NE     1 
ATOM   6208 C CZ     . ARG   F 1 209 ? 242.265 245.597 235.183 1.00 64.27  ? 221 ARG   A CZ     1 
ATOM   6209 N NH1    . ARG   F 1 209 ? 242.637 245.171 233.990 1.00 62.48  ? 221 ARG   A NH1    1 
ATOM   6210 N NH2    . ARG   F 1 209 ? 242.347 246.893 235.464 1.00 72.85  ? 221 ARG   A NH2    1 
ATOM   6211 N N      . MET   F 1 210 ? 239.977 244.008 230.570 1.00 51.29  ? 222 MET   A N      1 
ATOM   6212 C CA     . MET   F 1 210 ? 239.763 244.975 229.500 1.00 49.84  ? 222 MET   A CA     1 
ATOM   6213 C C      . MET   F 1 210 ? 238.506 244.656 228.699 1.00 48.76  ? 222 MET   A C      1 
ATOM   6214 O O      . MET   F 1 210 ? 237.903 245.560 228.110 1.00 47.79  ? 222 MET   A O      1 
ATOM   6215 C CB     . MET   F 1 210 ? 240.998 245.034 228.603 1.00 48.65  ? 222 MET   A CB     1 
ATOM   6216 C CG     . MET   F 1 210 ? 241.291 243.761 227.841 1.00 57.24  ? 222 MET   A CG     1 
ATOM   6217 S SD     . MET   F 1 210 ? 242.863 243.875 226.967 1.00 71.08  ? 222 MET   A SD     1 
ATOM   6218 C CE     . MET   F 1 210 ? 243.100 245.646 226.958 1.00 50.48  ? 222 MET   A CE     1 
ATOM   6219 N N      . CYS   F 1 211 ? 238.101 243.386 228.658 1.00 50.32  ? 223 CYS   A N      1 
ATOM   6220 C CA     . CYS   F 1 211 ? 236.810 243.048 228.069 1.00 49.65  ? 223 CYS   A CA     1 
ATOM   6221 C C      . CYS   F 1 211 ? 235.665 243.542 228.944 1.00 48.46  ? 223 CYS   A C      1 
ATOM   6222 O O      . CYS   F 1 211 ? 234.627 243.978 228.433 1.00 47.61  ? 223 CYS   A O      1 
ATOM   6223 C CB     . CYS   F 1 211 ? 236.712 241.539 227.854 1.00 53.60  ? 223 CYS   A CB     1 
ATOM   6224 S SG     . CYS   F 1 211 ? 237.045 240.994 226.168 1.00 65.43  ? 223 CYS   A SG     1 
ATOM   6225 N N      . ASN   F 1 212 ? 235.837 243.480 230.265 1.00 49.34  ? 224 ASN   A N      1 
ATOM   6226 C CA     . ASN   F 1 212 ? 234.785 243.929 231.169 1.00 47.39  ? 224 ASN   A CA     1 
ATOM   6227 C C      . ASN   F 1 212 ? 234.532 245.424 231.025 1.00 48.71  ? 224 ASN   A C      1 
ATOM   6228 O O      . ASN   F 1 212 ? 233.378 245.867 231.004 1.00 49.15  ? 224 ASN   A O      1 
ATOM   6229 C CB     . ASN   F 1 212 ? 235.156 243.583 232.610 1.00 48.53  ? 224 ASN   A CB     1 
ATOM   6230 C CG     . ASN   F 1 212 ? 234.622 242.236 233.040 1.00 53.50  ? 224 ASN   A CG     1 
ATOM   6231 O OD1    . ASN   F 1 212 ? 235.123 241.196 232.620 1.00 57.55  ? 224 ASN   A OD1    1 
ATOM   6232 N ND2    . ASN   F 1 212 ? 233.595 242.246 233.880 1.00 54.70  ? 224 ASN   A ND2    1 
ATOM   6233 N N      . ILE   F 1 213 ? 235.598 246.219 230.926 1.00 48.35  ? 225 ILE   A N      1 
ATOM   6234 C CA     . ILE   F 1 213 ? 235.425 247.658 230.763 1.00 47.93  ? 225 ILE   A CA     1 
ATOM   6235 C C      . ILE   F 1 213 ? 234.807 247.977 229.409 1.00 47.02  ? 225 ILE   A C      1 
ATOM   6236 O O      . ILE   F 1 213 ? 234.029 248.931 229.283 1.00 46.27  ? 225 ILE   A O      1 
ATOM   6237 C CB     . ILE   F 1 213 ? 236.765 248.388 230.972 1.00 46.67  ? 225 ILE   A CB     1 
ATOM   6238 C CG1    . ILE   F 1 213 ? 237.626 248.313 229.715 1.00 48.30  ? 225 ILE   A CG1    1 
ATOM   6239 C CG2    . ILE   F 1 213 ? 237.508 247.809 232.161 1.00 50.13  ? 225 ILE   A CG2    1 
ATOM   6240 C CD1    . ILE   F 1 213 ? 239.046 248.775 229.936 1.00 53.72  ? 225 ILE   A CD1    1 
ATOM   6241 N N      . LEU   F 1 214 ? 235.137 247.200 228.375 1.00 45.18  ? 226 LEU   A N      1 
ATOM   6242 C CA     . LEU   F 1 214 ? 234.479 247.380 227.086 1.00 45.19  ? 226 LEU   A CA     1 
ATOM   6243 C C      . LEU   F 1 214 ? 232.995 247.050 227.179 1.00 46.31  ? 226 LEU   A C      1 
ATOM   6244 O O      . LEU   F 1 214 ? 232.158 247.741 226.586 1.00 47.36  ? 226 LEU   A O      1 
ATOM   6245 C CB     . LEU   F 1 214 ? 235.161 246.521 226.023 1.00 44.87  ? 226 LEU   A CB     1 
ATOM   6246 C CG     . LEU   F 1 214 ? 234.466 246.428 224.664 1.00 46.56  ? 226 LEU   A CG     1 
ATOM   6247 C CD1    . LEU   F 1 214 ? 234.306 247.803 224.048 1.00 46.66  ? 226 LEU   A CD1    1 
ATOM   6248 C CD2    . LEU   F 1 214 ? 235.243 245.517 223.734 1.00 47.53  ? 226 LEU   A CD2    1 
ATOM   6249 N N      . LYS   F 1 215 ? 232.647 245.998 227.922 1.00 48.29  ? 227 LYS   A N      1 
ATOM   6250 C CA     . LYS   F 1 215 ? 231.242 245.643 228.086 1.00 48.37  ? 227 LYS   A CA     1 
ATOM   6251 C C      . LYS   F 1 215 ? 230.477 246.743 228.811 1.00 49.77  ? 227 LYS   A C      1 
ATOM   6252 O O      . LYS   F 1 215 ? 229.351 247.080 228.431 1.00 53.46  ? 227 LYS   A O      1 
ATOM   6253 C CB     . LYS   F 1 215 ? 231.121 244.314 228.831 1.00 48.92  ? 227 LYS   A CB     1 
ATOM   6254 C CG     . LYS   F 1 215 ? 229.859 244.167 229.658 1.00 47.37  ? 227 LYS   A CG     1 
ATOM   6255 C CD     . LYS   F 1 215 ? 230.010 243.061 230.686 1.00 47.16  ? 227 LYS   A CD     1 
ATOM   6256 C CE     . LYS   F 1 215 ? 228.721 242.286 230.858 1.00 48.09  ? 227 LYS   A CE     1 
ATOM   6257 N NZ     . LYS   F 1 215 ? 227.554 243.192 231.000 1.00 51.44  ? 227 LYS   A NZ     1 
ATOM   6258 N N      . GLY   F 1 216 ? 231.072 247.316 229.859 1.00 47.92  ? 228 GLY   A N      1 
ATOM   6259 C CA     . GLY   F 1 216 ? 230.440 248.428 230.545 1.00 46.49  ? 228 GLY   A CA     1 
ATOM   6260 C C      . GLY   F 1 216 ? 230.361 249.686 229.712 1.00 44.35  ? 228 GLY   A C      1 
ATOM   6261 O O      . GLY   F 1 216 ? 229.540 250.563 230.002 1.00 42.61  ? 228 GLY   A O      1 
ATOM   6262 N N      . LYS   F 1 217 ? 231.198 249.793 228.681 1.00 46.81  ? 229 LYS   A N      1 
ATOM   6263 C CA     . LYS   F 1 217 ? 231.153 250.950 227.798 1.00 47.28  ? 229 LYS   A CA     1 
ATOM   6264 C C      . LYS   F 1 217 ? 229.923 250.920 226.903 1.00 48.69  ? 229 LYS   A C      1 
ATOM   6265 O O      . LYS   F 1 217 ? 229.471 251.971 226.435 1.00 52.34  ? 229 LYS   A O      1 
ATOM   6266 C CB     . LYS   F 1 217 ? 232.428 251.000 226.957 1.00 43.98  ? 229 LYS   A CB     1 
ATOM   6267 C CG     . LYS   F 1 217 ? 232.808 252.377 226.467 1.00 48.89  ? 229 LYS   A CG     1 
ATOM   6268 C CD     . LYS   F 1 217 ? 234.302 252.463 226.210 1.00 48.83  ? 229 LYS   A CD     1 
ATOM   6269 C CE     . LYS   F 1 217 ? 235.089 252.481 227.507 1.00 41.20  ? 229 LYS   A CE     1 
ATOM   6270 N NZ     . LYS   F 1 217 ? 234.635 253.564 228.414 1.00 41.38  ? 229 LYS   A NZ     1 
ATOM   6271 N N      . PHE   F 1 218 ? 229.369 249.737 226.657 1.00 47.49  ? 230 PHE   A N      1 
ATOM   6272 C CA     . PHE   F 1 218 ? 228.236 249.598 225.760 1.00 48.17  ? 230 PHE   A CA     1 
ATOM   6273 C C      . PHE   F 1 218 ? 226.931 249.871 226.503 1.00 51.19  ? 230 PHE   A C      1 
ATOM   6274 O O      . PHE   F 1 218 ? 226.873 249.891 227.734 1.00 55.10  ? 230 PHE   A O      1 
ATOM   6275 C CB     . PHE   F 1 218 ? 228.217 248.206 225.137 1.00 47.73  ? 230 PHE   A CB     1 
ATOM   6276 C CG     . PHE   F 1 218 ? 229.117 248.069 223.947 1.00 45.91  ? 230 PHE   A CG     1 
ATOM   6277 C CD1    . PHE   F 1 218 ? 228.975 248.905 222.855 1.00 44.87  ? 230 PHE   A CD1    1 
ATOM   6278 C CD2    . PHE   F 1 218 ? 230.110 247.108 223.922 1.00 48.63  ? 230 PHE   A CD2    1 
ATOM   6279 C CE1    . PHE   F 1 218 ? 229.804 248.783 221.762 1.00 46.89  ? 230 PHE   A CE1    1 
ATOM   6280 C CE2    . PHE   F 1 218 ? 230.942 246.982 222.831 1.00 45.79  ? 230 PHE   A CE2    1 
ATOM   6281 C CZ     . PHE   F 1 218 ? 230.789 247.821 221.749 1.00 44.90  ? 230 PHE   A CZ     1 
ATOM   6282 N N      . GLN   F 1 219 ? 225.869 250.084 225.732 1.00 47.74  ? 231 GLN   A N      1 
ATOM   6283 C CA     . GLN   F 1 219 ? 224.576 250.453 226.291 1.00 49.93  ? 231 GLN   A CA     1 
ATOM   6284 C C      . GLN   F 1 219 ? 223.488 249.439 225.979 1.00 53.14  ? 231 GLN   A C      1 
ATOM   6285 O O      . GLN   F 1 219 ? 222.755 249.026 226.884 1.00 59.03  ? 231 GLN   A O      1 
ATOM   6286 C CB     . GLN   F 1 219 ? 224.172 251.840 225.772 1.00 52.34  ? 231 GLN   A CB     1 
ATOM   6287 C CG     . GLN   F 1 219 ? 224.747 252.984 226.581 1.00 54.01  ? 231 GLN   A CG     1 
ATOM   6288 C CD     . GLN   F 1 219 ? 224.333 254.335 226.047 1.00 60.52  ? 231 GLN   A CD     1 
ATOM   6289 O OE1    . GLN   F 1 219 ? 224.373 255.335 226.761 1.00 64.75  ? 231 GLN   A OE1    1 
ATOM   6290 N NE2    . GLN   F 1 219 ? 223.935 254.375 224.783 1.00 63.29  ? 231 GLN   A NE2    1 
ATOM   6291 N N      . THR   F 1 220 ? 223.359 249.025 224.724 1.00 48.88  ? 232 THR   A N      1 
ATOM   6292 C CA     . THR   F 1 220 ? 222.321 248.073 224.358 1.00 46.64  ? 232 THR   A CA     1 
ATOM   6293 C C      . THR   F 1 220 ? 222.636 246.695 224.923 1.00 46.59  ? 232 THR   A C      1 
ATOM   6294 O O      . THR   F 1 220 ? 223.797 246.285 225.000 1.00 44.97  ? 232 THR   A O      1 
ATOM   6295 C CB     . THR   F 1 220 ? 222.175 247.998 222.839 1.00 48.10  ? 232 THR   A CB     1 
ATOM   6296 O OG1    . THR   F 1 220 ? 223.362 247.433 222.271 1.00 54.75  ? 232 THR   A OG1    1 
ATOM   6297 C CG2    . THR   F 1 220 ? 221.957 249.383 222.261 1.00 48.68  ? 232 THR   A CG2    1 
ATOM   6298 N N      . ALA   F 1 221 ? 221.585 245.976 225.321 1.00 46.04  ? 233 ALA   A N      1 
ATOM   6299 C CA     . ALA   F 1 221 ? 221.776 244.660 225.917 1.00 46.41  ? 233 ALA   A CA     1 
ATOM   6300 C C      . ALA   F 1 221 ? 222.404 243.688 224.927 1.00 47.61  ? 233 ALA   A C      1 
ATOM   6301 O O      . ALA   F 1 221 ? 223.149 242.786 225.323 1.00 45.38  ? 233 ALA   A O      1 
ATOM   6302 C CB     . ALA   F 1 221 ? 220.443 244.119 226.429 1.00 44.85  ? 233 ALA   A CB     1 
ATOM   6303 N N      . ALA   F 1 222 ? 222.111 243.853 223.636 1.00 46.69  ? 234 ALA   A N      1 
ATOM   6304 C CA     . ALA   F 1 222 ? 222.668 242.952 222.632 1.00 46.93  ? 234 ALA   A CA     1 
ATOM   6305 C C      . ALA   F 1 222 ? 224.186 243.063 222.563 1.00 47.97  ? 234 ALA   A C      1 
ATOM   6306 O O      . ALA   F 1 222 ? 224.885 242.047 222.478 1.00 50.27  ? 234 ALA   A O      1 
ATOM   6307 C CB     . ALA   F 1 222 ? 222.045 243.242 221.268 1.00 46.29  ? 234 ALA   A CB     1 
ATOM   6308 N N      . GLN   F 1 223 ? 224.713 244.287 222.593 1.00 47.13  ? 235 GLN   A N      1 
ATOM   6309 C CA     . GLN   F 1 223 ? 226.157 244.473 222.503 1.00 45.19  ? 235 GLN   A CA     1 
ATOM   6310 C C      . GLN   F 1 223 ? 226.867 243.886 223.715 1.00 49.26  ? 235 GLN   A C      1 
ATOM   6311 O O      . GLN   F 1 223 ? 227.939 243.284 223.585 1.00 50.48  ? 235 GLN   A O      1 
ATOM   6312 C CB     . GLN   F 1 223 ? 226.483 245.958 222.351 1.00 44.73  ? 235 GLN   A CB     1 
ATOM   6313 C CG     . GLN   F 1 223 ? 226.495 246.444 220.914 1.00 44.01  ? 235 GLN   A CG     1 
ATOM   6314 C CD     . GLN   F 1 223 ? 226.266 247.935 220.800 1.00 43.02  ? 235 GLN   A CD     1 
ATOM   6315 O OE1    . GLN   F 1 223 ? 225.485 248.513 221.552 1.00 47.11  ? 235 GLN   A OE1    1 
ATOM   6316 N NE2    . GLN   F 1 223 ? 226.951 248.568 219.858 1.00 45.23  ? 235 GLN   A NE2    1 
ATOM   6317 N N      . ARG   F 1 224 ? 226.286 244.051 224.905 1.00 50.55  ? 236 ARG   A N      1 
ATOM   6318 C CA     . ARG   F 1 224 ? 226.909 243.509 226.108 1.00 49.73  ? 236 ARG   A CA     1 
ATOM   6319 C C      . ARG   F 1 224 ? 226.994 241.991 226.049 1.00 50.06  ? 236 ARG   A C      1 
ATOM   6320 O O      . ARG   F 1 224 ? 228.003 241.402 226.451 1.00 51.77  ? 236 ARG   A O      1 
ATOM   6321 C CB     . ARG   F 1 224 ? 226.131 243.945 227.347 1.00 50.21  ? 236 ARG   A CB     1 
ATOM   6322 C CG     . ARG   F 1 224 ? 225.800 245.418 227.396 1.00 49.85  ? 236 ARG   A CG     1 
ATOM   6323 C CD     . ARG   F 1 224 ? 224.728 245.686 228.431 1.00 50.58  ? 236 ARG   A CD     1 
ATOM   6324 N NE     . ARG   F 1 224 ? 224.873 247.004 229.033 1.00 53.98  ? 236 ARG   A NE     1 
ATOM   6325 C CZ     . ARG   F 1 224 ? 225.538 247.242 230.153 1.00 58.69  ? 236 ARG   A CZ     1 
ATOM   6326 N NH1    . ARG   F 1 224 ? 226.147 246.272 230.813 1.00 56.58  ? 236 ARG   A NH1    1 
ATOM   6327 N NH2    . ARG   F 1 224 ? 225.598 248.485 230.620 1.00 64.41  ? 236 ARG   A NH2    1 
ATOM   6328 N N      . THR   F 1 225 ? 225.935 241.338 225.569 1.00 49.26  ? 237 THR   A N      1 
ATOM   6329 C CA     . THR   F 1 225 ? 225.940 239.881 225.502 1.00 49.43  ? 237 THR   A CA     1 
ATOM   6330 C C      . THR   F 1 225 ? 227.013 239.371 224.550 1.00 50.31  ? 237 THR   A C      1 
ATOM   6331 O O      . THR   F 1 225 ? 227.723 238.408 224.862 1.00 52.97  ? 237 THR   A O      1 
ATOM   6332 C CB     . THR   F 1 225 ? 224.564 239.368 225.083 1.00 53.64  ? 237 THR   A CB     1 
ATOM   6333 O OG1    . THR   F 1 225 ? 223.589 239.771 226.052 1.00 55.91  ? 237 THR   A OG1    1 
ATOM   6334 C CG2    . THR   F 1 225 ? 224.572 237.852 224.982 1.00 60.28  ? 237 THR   A CG2    1 
ATOM   6335 N N      . MET   F 1 226 ? 227.150 240.000 223.380 1.00 48.09  ? 238 MET   A N      1 
ATOM   6336 C CA     . MET   F 1 226 ? 228.154 239.544 222.425 1.00 48.33  ? 238 MET   A CA     1 
ATOM   6337 C C      . MET   F 1 226 ? 229.564 239.759 222.959 1.00 48.85  ? 238 MET   A C      1 
ATOM   6338 O O      . MET   F 1 226 ? 230.435 238.898 222.788 1.00 48.82  ? 238 MET   A O      1 
ATOM   6339 C CB     . MET   F 1 226 ? 227.973 240.249 221.081 1.00 46.29  ? 238 MET   A CB     1 
ATOM   6340 C CG     . MET   F 1 226 ? 229.245 240.312 220.251 1.00 55.49  ? 238 MET   A CG     1 
ATOM   6341 S SD     . MET   F 1 226 ? 228.982 239.979 218.499 1.00 60.93  ? 238 MET   A SD     1 
ATOM   6342 C CE     . MET   F 1 226 ? 227.700 241.163 218.118 1.00 52.01  ? 238 MET   A CE     1 
ATOM   6343 N N      . VAL   F 1 227 ? 229.815 240.900 223.604 1.00 48.72  ? 239 VAL   A N      1 
ATOM   6344 C CA     . VAL   F 1 227 ? 231.124 241.107 224.211 1.00 50.31  ? 239 VAL   A CA     1 
ATOM   6345 C C      . VAL   F 1 227 ? 231.334 240.122 225.349 1.00 52.73  ? 239 VAL   A C      1 
ATOM   6346 O O      . VAL   F 1 227 ? 232.468 239.720 225.635 1.00 55.46  ? 239 VAL   A O      1 
ATOM   6347 C CB     . VAL   F 1 227 ? 231.286 242.564 224.681 1.00 48.30  ? 239 VAL   A CB     1 
ATOM   6348 C CG1    . VAL   F 1 227 ? 230.324 242.869 225.810 1.00 53.69  ? 239 VAL   A CG1    1 
ATOM   6349 C CG2    . VAL   F 1 227 ? 232.717 242.818 225.116 1.00 46.35  ? 239 VAL   A CG2    1 
ATOM   6350 N N      . ASP   F 1 228 ? 230.253 239.716 226.016 1.00 51.34  ? 240 ASP   A N      1 
ATOM   6351 C CA     . ASP   F 1 228 ? 230.355 238.666 227.021 1.00 51.55  ? 240 ASP   A CA     1 
ATOM   6352 C C      . ASP   F 1 228 ? 230.805 237.354 226.389 1.00 52.42  ? 240 ASP   A C      1 
ATOM   6353 O O      . ASP   F 1 228 ? 231.624 236.627 226.961 1.00 51.79  ? 240 ASP   A O      1 
ATOM   6354 C CB     . ASP   F 1 228 ? 229.011 238.500 227.729 1.00 52.44  ? 240 ASP   A CB     1 
ATOM   6355 C CG     . ASP   F 1 228 ? 229.153 238.377 229.230 1.00 57.97  ? 240 ASP   A CG     1 
ATOM   6356 O OD1    . ASP   F 1 228 ? 230.301 238.356 229.718 1.00 66.02  ? 240 ASP   A OD1    1 
ATOM   6357 O OD2    . ASP   F 1 228 ? 228.117 238.313 229.922 1.00 55.94  ? 240 ASP   A OD2    1 
ATOM   6358 N N      . GLN   F 1 229 ? 230.277 237.038 225.203 1.00 55.73  ? 241 GLN   A N      1 
ATOM   6359 C CA     . GLN   F 1 229 ? 230.682 235.824 224.500 1.00 53.63  ? 241 GLN   A CA     1 
ATOM   6360 C C      . GLN   F 1 229 ? 232.155 235.869 224.116 1.00 53.71  ? 241 GLN   A C      1 
ATOM   6361 O O      . GLN   F 1 229 ? 232.867 234.866 224.240 1.00 56.52  ? 241 GLN   A O      1 
ATOM   6362 C CB     . GLN   F 1 229 ? 229.814 235.626 223.257 1.00 53.91  ? 241 GLN   A CB     1 
ATOM   6363 C CG     . GLN   F 1 229 ? 228.621 234.714 223.470 1.00 56.47  ? 241 GLN   A CG     1 
ATOM   6364 C CD     . GLN   F 1 229 ? 227.470 235.036 222.541 1.00 62.34  ? 241 GLN   A CD     1 
ATOM   6365 O OE1    . GLN   F 1 229 ? 227.515 236.012 221.794 1.00 59.45  ? 241 GLN   A OE1    1 
ATOM   6366 N NE2    . GLN   F 1 229 ? 226.427 234.217 222.584 1.00 66.83  ? 241 GLN   A NE2    1 
ATOM   6367 N N      . VAL   F 1 230 ? 232.629 237.021 223.642 1.00 54.03  ? 242 VAL   A N      1 
ATOM   6368 C CA     . VAL   F 1 230 ? 234.023 237.131 223.224 1.00 55.21  ? 242 VAL   A CA     1 
ATOM   6369 C C      . VAL   F 1 230 ? 234.950 236.923 224.413 1.00 54.68  ? 242 VAL   A C      1 
ATOM   6370 O O      . VAL   F 1 230 ? 236.036 236.347 224.282 1.00 55.80  ? 242 VAL   A O      1 
ATOM   6371 C CB     . VAL   F 1 230 ? 234.272 238.487 222.540 1.00 51.94  ? 242 VAL   A CB     1 
ATOM   6372 C CG1    . VAL   F 1 230 ? 235.756 238.694 222.306 1.00 54.08  ? 242 VAL   A CG1    1 
ATOM   6373 C CG2    . VAL   F 1 230 ? 233.507 238.568 221.233 1.00 53.65  ? 242 VAL   A CG2    1 
ATOM   6374 N N      . ARG   F 1 231 ? 234.537 237.391 225.590 1.00 53.09  ? 243 ARG   A N      1 
ATOM   6375 C CA     . ARG   F 1 231 ? 235.347 237.206 226.789 1.00 54.86  ? 243 ARG   A CA     1 
ATOM   6376 C C      . ARG   F 1 231 ? 235.469 235.733 227.158 1.00 60.12  ? 243 ARG   A C      1 
ATOM   6377 O O      . ARG   F 1 231 ? 236.541 235.276 227.570 1.00 67.32  ? 243 ARG   A O      1 
ATOM   6378 C CB     . ARG   F 1 231 ? 234.745 238.000 227.944 1.00 57.20  ? 243 ARG   A CB     1 
ATOM   6379 C CG     . ARG   F 1 231 ? 235.307 237.644 229.298 1.00 60.06  ? 243 ARG   A CG     1 
ATOM   6380 C CD     . ARG   F 1 231 ? 234.662 238.484 230.373 1.00 58.11  ? 243 ARG   A CD     1 
ATOM   6381 N NE     . ARG   F 1 231 ? 233.238 238.196 230.477 1.00 54.75  ? 243 ARG   A NE     1 
ATOM   6382 C CZ     . ARG   F 1 231 ? 232.592 238.024 231.620 1.00 62.58  ? 243 ARG   A CZ     1 
ATOM   6383 N NH1    . ARG   F 1 231 ? 233.214 238.104 232.784 1.00 69.97  ? 243 ARG   A NH1    1 
ATOM   6384 N NH2    . ARG   F 1 231 ? 231.290 237.760 231.596 1.00 67.17  ? 243 ARG   A NH2    1 
ATOM   6385 N N      . GLU   F 1 232 ? 234.379 234.973 227.023 1.00 58.38  ? 244 GLU   A N      1 
ATOM   6386 C CA     . GLU   F 1 232 ? 234.372 233.574 227.436 1.00 58.42  ? 244 GLU   A CA     1 
ATOM   6387 C C      . GLU   F 1 232 ? 235.312 232.696 226.620 1.00 62.84  ? 244 GLU   A C      1 
ATOM   6388 O O      . GLU   F 1 232 ? 235.622 231.585 227.061 1.00 69.71  ? 244 GLU   A O      1 
ATOM   6389 C CB     . GLU   F 1 232 ? 232.955 233.005 227.354 1.00 61.15  ? 244 GLU   A CB     1 
ATOM   6390 C CG     . GLU   F 1 232 ? 231.882 233.885 227.968 1.00 59.34  ? 244 GLU   A CG     1 
ATOM   6391 C CD     . GLU   F 1 232 ? 232.013 233.996 229.472 1.00 69.43  ? 244 GLU   A CD     1 
ATOM   6392 O OE1    . GLU   F 1 232 ? 233.155 233.998 229.975 1.00 74.25  ? 244 GLU   A OE1    1 
ATOM   6393 O OE2    . GLU   F 1 232 ? 230.970 234.075 230.153 1.00 70.37  ? 244 GLU   A OE2    1 
ATOM   6394 N N      . SER   F 1 233 ? 235.768 233.150 225.455 1.00 60.64  ? 245 SER   A N      1 
ATOM   6395 C CA     . SER   F 1 233 ? 236.638 232.330 224.621 1.00 64.24  ? 245 SER   A CA     1 
ATOM   6396 C C      . SER   F 1 233 ? 237.983 232.097 225.298 1.00 67.72  ? 245 SER   A C      1 
ATOM   6397 O O      . SER   F 1 233 ? 238.721 233.048 225.574 1.00 71.10  ? 245 SER   A O      1 
ATOM   6398 C CB     . SER   F 1 233 ? 236.837 232.982 223.252 1.00 69.39  ? 245 SER   A CB     1 
ATOM   6399 O OG     . SER   F 1 233 ? 235.620 233.019 222.529 1.00 73.09  ? 245 SER   A OG     1 
ATOM   6400 N N      . ARG   F 1 234 ? 238.306 230.832 225.571 1.00 68.74  ? 246 ARG   A N      1 
ATOM   6401 C CA     . ARG   F 1 234 ? 239.560 230.515 226.248 1.00 70.18  ? 246 ARG   A CA     1 
ATOM   6402 C C      . ARG   F 1 234 ? 240.755 230.712 225.324 1.00 72.75  ? 246 ARG   A C      1 
ATOM   6403 O O      . ARG   F 1 234 ? 241.830 231.131 225.769 1.00 68.19  ? 246 ARG   A O      1 
ATOM   6404 C CB     . ARG   F 1 234 ? 239.519 229.082 226.773 1.00 79.27  ? 246 ARG   A CB     1 
ATOM   6405 C CG     . ARG   F 1 234 ? 238.421 228.828 227.792 1.00 84.25  ? 246 ARG   A CG     1 
ATOM   6406 C CD     . ARG   F 1 234 ? 238.506 229.796 228.957 1.00 74.98  ? 246 ARG   A CD     1 
ATOM   6407 N NE     . ARG   F 1 234 ? 239.840 229.828 229.540 1.00 76.91  ? 246 ARG   A NE     1 
ATOM   6408 C CZ     . ARG   F 1 234 ? 240.190 230.598 230.560 1.00 78.81  ? 246 ARG   A CZ     1 
ATOM   6409 N NH1    . ARG   F 1 234 ? 239.323 231.411 231.140 1.00 77.89  ? 246 ARG   A NH1    1 
ATOM   6410 N NH2    . ARG   F 1 234 ? 241.440 230.547 231.012 1.00 80.88  ? 246 ARG   A NH2    1 
ATOM   6411 N N      . ASN   F 1 235 ? 240.591 230.403 224.035 1.00 75.07  ? 247 ASN   A N      1 
ATOM   6412 C CA     . ASN   F 1 235 ? 241.628 230.575 223.020 1.00 72.72  ? 247 ASN   A CA     1 
ATOM   6413 C C      . ASN   F 1 235 ? 241.029 231.377 221.872 1.00 79.30  ? 247 ASN   A C      1 
ATOM   6414 O O      . ASN   F 1 235 ? 240.690 230.816 220.819 1.00 86.62  ? 247 ASN   A O      1 
ATOM   6415 C CB     . ASN   F 1 235 ? 242.165 229.232 222.530 1.00 79.96  ? 247 ASN   A CB     1 
ATOM   6416 C CG     . ASN   F 1 235 ? 243.423 229.376 221.705 1.00 89.50  ? 247 ASN   A CG     1 
ATOM   6417 O OD1    . ASN   F 1 235 ? 244.218 230.289 221.920 1.00 89.07  ? 247 ASN   A OD1    1 
ATOM   6418 N ND2    . ASN   F 1 235 ? 243.613 228.470 220.752 1.00 96.12  ? 247 ASN   A ND2    1 
ATOM   6419 N N      . PRO   F 1 236 ? 240.878 232.688 222.039 1.00 72.45  ? 248 PRO   A N      1 
ATOM   6420 C CA     . PRO   F 1 236 ? 240.270 233.497 220.979 1.00 68.99  ? 248 PRO   A CA     1 
ATOM   6421 C C      . PRO   F 1 236 ? 241.095 233.454 219.702 1.00 65.59  ? 248 PRO   A C      1 
ATOM   6422 O O      . PRO   F 1 236 ? 242.325 233.385 219.730 1.00 62.88  ? 248 PRO   A O      1 
ATOM   6423 C CB     . PRO   F 1 236 ? 240.239 234.906 221.579 1.00 71.71  ? 248 PRO   A CB     1 
ATOM   6424 C CG     . PRO   F 1 236 ? 241.282 234.889 222.646 1.00 67.51  ? 248 PRO   A CG     1 
ATOM   6425 C CD     . PRO   F 1 236 ? 241.287 233.500 223.195 1.00 68.27  ? 248 PRO   A CD     1 
ATOM   6426 N N      . GLY   F 1 237 ? 240.396 233.498 218.572 1.00 64.50  ? 249 GLY   A N      1 
ATOM   6427 C CA     . GLY   F 1 237 ? 241.052 233.458 217.281 1.00 63.36  ? 249 GLY   A CA     1 
ATOM   6428 C C      . GLY   F 1 237 ? 240.418 234.375 216.259 1.00 65.76  ? 249 GLY   A C      1 
ATOM   6429 O O      . GLY   F 1 237 ? 240.012 235.494 216.585 1.00 70.58  ? 249 GLY   A O      1 
ATOM   6430 N N      . ASN   F 1 238 ? 240.325 233.908 215.013 1.00 64.70  ? 250 ASN   A N      1 
ATOM   6431 C CA     . ASN   F 1 238 ? 239.760 234.737 213.955 1.00 66.75  ? 250 ASN   A CA     1 
ATOM   6432 C C      . ASN   F 1 238 ? 238.284 235.028 214.191 1.00 66.75  ? 250 ASN   A C      1 
ATOM   6433 O O      . ASN   F 1 238 ? 237.814 236.125 213.872 1.00 66.42  ? 250 ASN   A O      1 
ATOM   6434 C CB     . ASN   F 1 238 ? 239.959 234.061 212.599 1.00 70.56  ? 250 ASN   A CB     1 
ATOM   6435 C CG     . ASN   F 1 238 ? 239.727 235.005 211.438 1.00 83.15  ? 250 ASN   A CG     1 
ATOM   6436 O OD1    . ASN   F 1 238 ? 240.318 234.851 210.370 1.00 91.39  ? 250 ASN   A OD1    1 
ATOM   6437 N ND2    . ASN   F 1 238 ? 238.861 235.992 211.640 1.00 79.38  ? 250 ASN   A ND2    1 
ATOM   6438 N N      . ALA   F 1 239 ? 237.537 234.066 214.738 1.00 68.27  ? 251 ALA   A N      1 
ATOM   6439 C CA     . ALA   F 1 239 ? 236.122 234.304 215.005 1.00 66.74  ? 251 ALA   A CA     1 
ATOM   6440 C C      . ALA   F 1 239 ? 235.935 235.457 215.980 1.00 67.29  ? 251 ALA   A C      1 
ATOM   6441 O O      . ALA   F 1 239 ? 235.116 236.353 215.744 1.00 69.51  ? 251 ALA   A O      1 
ATOM   6442 C CB     . ALA   F 1 239 ? 235.465 233.034 215.543 1.00 71.21  ? 251 ALA   A CB     1 
ATOM   6443 N N      . GLU   F 1 240 ? 236.691 235.456 217.080 1.00 65.85  ? 252 GLU   A N      1 
ATOM   6444 C CA     . GLU   F 1 240 ? 236.641 236.578 218.011 1.00 62.76  ? 252 GLU   A CA     1 
ATOM   6445 C C      . GLU   F 1 240 ? 237.204 237.847 217.385 1.00 61.36  ? 252 GLU   A C      1 
ATOM   6446 O O      . GLU   F 1 240 ? 236.873 238.954 217.821 1.00 59.99  ? 252 GLU   A O      1 
ATOM   6447 C CB     . GLU   F 1 240 ? 237.392 236.232 219.295 1.00 63.83  ? 252 GLU   A CB     1 
ATOM   6448 C CG     . GLU   F 1 240 ? 236.822 235.039 220.036 1.00 69.77  ? 252 GLU   A CG     1 
ATOM   6449 C CD     . GLU   F 1 240 ? 237.319 233.721 219.479 1.00 82.69  ? 252 GLU   A CD     1 
ATOM   6450 O OE1    . GLU   F 1 240 ? 237.751 233.694 218.307 1.00 81.36  ? 252 GLU   A OE1    1 
ATOM   6451 O OE2    . GLU   F 1 240 ? 237.281 232.713 220.215 1.00 88.48  ? 252 GLU   A OE2    1 
ATOM   6452 N N      . PHE   F 1 241 ? 238.080 237.708 216.392 1.00 63.41  ? 253 PHE   A N      1 
ATOM   6453 C CA     . PHE   F 1 241 ? 238.496 238.862 215.605 1.00 58.10  ? 253 PHE   A CA     1 
ATOM   6454 C C      . PHE   F 1 241 ? 237.295 239.517 214.930 1.00 57.17  ? 253 PHE   A C      1 
ATOM   6455 O O      . PHE   F 1 241 ? 237.124 240.740 214.986 1.00 58.94  ? 253 PHE   A O      1 
ATOM   6456 C CB     . PHE   F 1 241 ? 239.532 238.418 214.572 1.00 63.67  ? 253 PHE   A CB     1 
ATOM   6457 C CG     . PHE   F 1 241 ? 240.341 239.536 213.982 1.00 61.55  ? 253 PHE   A CG     1 
ATOM   6458 C CD1    . PHE   F 1 241 ? 239.736 240.572 213.297 1.00 66.12  ? 253 PHE   A CD1    1 
ATOM   6459 C CD2    . PHE   F 1 241 ? 241.719 239.530 214.090 1.00 59.54  ? 253 PHE   A CD2    1 
ATOM   6460 C CE1    . PHE   F 1 241 ? 240.488 241.588 212.748 1.00 65.88  ? 253 PHE   A CE1    1 
ATOM   6461 C CE2    . PHE   F 1 241 ? 242.475 240.542 213.543 1.00 62.33  ? 253 PHE   A CE2    1 
ATOM   6462 C CZ     . PHE   F 1 241 ? 241.860 241.572 212.872 1.00 63.68  ? 253 PHE   A CZ     1 
ATOM   6463 N N      . GLU   F 1 242 ? 236.444 238.707 214.296 1.00 58.55  ? 254 GLU   A N      1 
ATOM   6464 C CA     . GLU   F 1 242 ? 235.357 239.246 213.483 1.00 56.77  ? 254 GLU   A CA     1 
ATOM   6465 C C      . GLU   F 1 242 ? 234.297 239.936 214.332 1.00 55.58  ? 254 GLU   A C      1 
ATOM   6466 O O      . GLU   F 1 242 ? 233.849 241.036 213.993 1.00 57.45  ? 254 GLU   A O      1 
ATOM   6467 C CB     . GLU   F 1 242 ? 234.730 238.129 212.651 1.00 64.16  ? 254 GLU   A CB     1 
ATOM   6468 C CG     . GLU   F 1 242 ? 235.723 237.394 211.781 1.00 69.43  ? 254 GLU   A CG     1 
ATOM   6469 C CD     . GLU   F 1 242 ? 236.483 238.330 210.868 1.00 75.33  ? 254 GLU   A CD     1 
ATOM   6470 O OE1    . GLU   F 1 242 ? 236.031 239.480 210.687 1.00 72.74  ? 254 GLU   A OE1    1 
ATOM   6471 O OE2    . GLU   F 1 242 ? 237.539 237.923 210.341 1.00 82.46  ? 254 GLU   A OE2    1 
ATOM   6472 N N      . ASP   F 1 243 ? 233.876 239.308 215.432 1.00 54.97  ? 255 ASP   A N      1 
ATOM   6473 C CA     . ASP   F 1 243 ? 232.791 239.881 216.222 1.00 54.86  ? 255 ASP   A CA     1 
ATOM   6474 C C      . ASP   F 1 243 ? 233.218 241.190 216.871 1.00 52.28  ? 255 ASP   A C      1 
ATOM   6475 O O      . ASP   F 1 243 ? 232.401 242.102 217.039 1.00 53.58  ? 255 ASP   A O      1 
ATOM   6476 C CB     . ASP   F 1 243 ? 232.304 238.886 217.276 1.00 62.75  ? 255 ASP   A CB     1 
ATOM   6477 C CG     . ASP   F 1 243 ? 233.430 238.106 217.907 1.00 69.94  ? 255 ASP   A CG     1 
ATOM   6478 O OD1    . ASP   F 1 243 ? 233.225 236.923 218.247 1.00 74.52  ? 255 ASP   A OD1    1 
ATOM   6479 O OD2    . ASP   F 1 243 ? 234.516 238.690 218.084 1.00 66.95  ? 255 ASP   A OD2    1 
ATOM   6480 N N      . LEU   F 1 244 ? 234.493 241.302 217.251 1.00 52.28  ? 256 LEU   A N      1 
ATOM   6481 C CA     . LEU   F 1 244 ? 235.000 242.578 217.742 1.00 50.30  ? 256 LEU   A CA     1 
ATOM   6482 C C      . LEU   F 1 244 ? 234.960 243.648 216.658 1.00 49.23  ? 256 LEU   A C      1 
ATOM   6483 O O      . LEU   F 1 244 ? 234.637 244.807 216.944 1.00 48.90  ? 256 LEU   A O      1 
ATOM   6484 C CB     . LEU   F 1 244 ? 236.421 242.410 218.277 1.00 51.91  ? 256 LEU   A CB     1 
ATOM   6485 C CG     . LEU   F 1 244 ? 236.549 241.816 219.680 1.00 52.39  ? 256 LEU   A CG     1 
ATOM   6486 C CD1    . LEU   F 1 244 ? 237.976 241.375 219.936 1.00 53.97  ? 256 LEU   A CD1    1 
ATOM   6487 C CD2    . LEU   F 1 244 ? 236.101 242.817 220.729 1.00 52.35  ? 256 LEU   A CD2    1 
ATOM   6488 N N      . ILE   F 1 245 ? 235.285 243.284 215.416 1.00 50.61  ? 257 ILE   A N      1 
ATOM   6489 C CA     . ILE   F 1 245 ? 235.162 244.228 214.309 1.00 48.32  ? 257 ILE   A CA     1 
ATOM   6490 C C      . ILE   F 1 245 ? 233.704 244.612 214.102 1.00 46.95  ? 257 ILE   A C      1 
ATOM   6491 O O      . ILE   F 1 245 ? 233.375 245.788 213.908 1.00 48.34  ? 257 ILE   A O      1 
ATOM   6492 C CB     . ILE   F 1 245 ? 235.780 243.635 213.029 1.00 50.13  ? 257 ILE   A CB     1 
ATOM   6493 C CG1    . ILE   F 1 245 ? 237.302 243.774 213.051 1.00 44.87  ? 257 ILE   A CG1    1 
ATOM   6494 C CG2    . ILE   F 1 245 ? 235.215 244.320 211.800 1.00 53.18  ? 257 ILE   A CG2    1 
ATOM   6495 C CD1    . ILE   F 1 245 ? 237.778 245.200 213.110 1.00 53.05  ? 257 ILE   A CD1    1 
ATOM   6496 N N      . PHE   F 1 246 ? 232.806 243.626 214.145 1.00 49.41  ? 258 PHE   A N      1 
ATOM   6497 C CA     . PHE   F 1 246 ? 231.382 243.913 214.026 1.00 50.24  ? 258 PHE   A CA     1 
ATOM   6498 C C      . PHE   F 1 246 ? 230.902 244.790 215.176 1.00 51.09  ? 258 PHE   A C      1 
ATOM   6499 O O      . PHE   F 1 246 ? 230.104 245.713 214.974 1.00 51.51  ? 258 PHE   A O      1 
ATOM   6500 C CB     . PHE   F 1 246 ? 230.593 242.605 213.979 1.00 48.33  ? 258 PHE   A CB     1 
ATOM   6501 C CG     . PHE   F 1 246 ? 229.107 242.793 213.972 1.00 48.58  ? 258 PHE   A CG     1 
ATOM   6502 C CD1    . PHE   F 1 246 ? 228.437 243.055 212.794 1.00 51.91  ? 258 PHE   A CD1    1 
ATOM   6503 C CD2    . PHE   F 1 246 ? 228.379 242.701 215.143 1.00 49.58  ? 258 PHE   A CD2    1 
ATOM   6504 C CE1    . PHE   F 1 246 ? 227.071 243.224 212.783 1.00 53.09  ? 258 PHE   A CE1    1 
ATOM   6505 C CE2    . PHE   F 1 246 ? 227.013 242.872 215.136 1.00 49.53  ? 258 PHE   A CE2    1 
ATOM   6506 C CZ     . PHE   F 1 246 ? 226.359 243.133 213.955 1.00 50.96  ? 258 PHE   A CZ     1 
ATOM   6507 N N      . LEU   F 1 247 ? 231.373 244.512 216.392 1.00 51.19  ? 259 LEU   A N      1 
ATOM   6508 C CA     . LEU   F 1 247 ? 231.000 245.336 217.537 1.00 49.15  ? 259 LEU   A CA     1 
ATOM   6509 C C      . LEU   F 1 247 ? 231.480 246.771 217.358 1.00 49.12  ? 259 LEU   A C      1 
ATOM   6510 O O      . LEU   F 1 247 ? 230.776 247.719 217.723 1.00 46.99  ? 259 LEU   A O      1 
ATOM   6511 C CB     . LEU   F 1 247 ? 231.570 244.733 218.820 1.00 47.18  ? 259 LEU   A CB     1 
ATOM   6512 C CG     . LEU   F 1 247 ? 230.589 243.967 219.707 1.00 47.47  ? 259 LEU   A CG     1 
ATOM   6513 C CD1    . LEU   F 1 247 ? 231.249 243.580 221.016 1.00 46.17  ? 259 LEU   A CD1    1 
ATOM   6514 C CD2    . LEU   F 1 247 ? 229.342 244.793 219.958 1.00 50.62  ? 259 LEU   A CD2    1 
ATOM   6515 N N      . ALA   F 1 248 ? 232.683 246.947 216.810 1.00 49.38  ? 260 ALA   A N      1 
ATOM   6516 C CA     . ALA   F 1 248 ? 233.181 248.290 216.534 1.00 45.39  ? 260 ALA   A CA     1 
ATOM   6517 C C      . ALA   F 1 248 ? 232.307 249.003 215.512 1.00 46.11  ? 260 ALA   A C      1 
ATOM   6518 O O      . ALA   F 1 248 ? 231.999 250.190 215.665 1.00 48.63  ? 260 ALA   A O      1 
ATOM   6519 C CB     . ALA   F 1 248 ? 234.628 248.221 216.051 1.00 43.60  ? 260 ALA   A CB     1 
ATOM   6520 N N      . ARG   F 1 249 ? 231.896 248.293 214.460 1.00 47.04  ? 261 ARG   A N      1 
ATOM   6521 C CA     . ARG   F 1 249 ? 231.048 248.906 213.444 1.00 46.87  ? 261 ARG   A CA     1 
ATOM   6522 C C      . ARG   F 1 249 ? 229.680 249.267 214.011 1.00 45.56  ? 261 ARG   A C      1 
ATOM   6523 O O      . ARG   F 1 249 ? 229.083 250.276 213.617 1.00 46.72  ? 261 ARG   A O      1 
ATOM   6524 C CB     . ARG   F 1 249 ? 230.907 247.969 212.245 1.00 48.74  ? 261 ARG   A CB     1 
ATOM   6525 C CG     . ARG   F 1 249 ? 230.517 248.670 210.960 1.00 48.32  ? 261 ARG   A CG     1 
ATOM   6526 C CD     . ARG   F 1 249 ? 231.086 247.967 209.741 1.00 46.28  ? 261 ARG   A CD     1 
ATOM   6527 N NE     . ARG   F 1 249 ? 232.516 247.719 209.865 1.00 48.19  ? 261 ARG   A NE     1 
ATOM   6528 C CZ     . ARG   F 1 249 ? 233.228 247.000 209.009 1.00 50.83  ? 261 ARG   A CZ     1 
ATOM   6529 N NH1    . ARG   F 1 249 ? 232.673 246.441 207.947 1.00 54.52  ? 261 ARG   A NH1    1 
ATOM   6530 N NH2    . ARG   F 1 249 ? 234.530 246.840 209.221 1.00 54.10  ? 261 ARG   A NH2    1 
ATOM   6531 N N      . SER   F 1 250 ? 229.163 248.452 214.931 1.00 44.95  ? 262 SER   A N      1 
ATOM   6532 C CA     . SER   F 1 250 ? 227.877 248.761 215.544 1.00 45.70  ? 262 SER   A CA     1 
ATOM   6533 C C      . SER   F 1 250 ? 227.959 249.995 216.432 1.00 43.68  ? 262 SER   A C      1 
ATOM   6534 O O      . SER   F 1 250 ? 226.946 250.667 216.650 1.00 44.04  ? 262 SER   A O      1 
ATOM   6535 C CB     . SER   F 1 250 ? 227.375 247.564 216.348 1.00 49.49  ? 262 SER   A CB     1 
ATOM   6536 O OG     . SER   F 1 250 ? 228.143 247.384 217.523 1.00 54.13  ? 262 SER   A OG     1 
ATOM   6537 N N      . ALA   F 1 251 ? 229.147 250.307 216.952 1.00 42.25  ? 263 ALA   A N      1 
ATOM   6538 C CA     . ALA   F 1 251 ? 229.299 251.469 217.818 1.00 41.78  ? 263 ALA   A CA     1 
ATOM   6539 C C      . ALA   F 1 251 ? 229.101 252.780 217.072 1.00 42.79  ? 263 ALA   A C      1 
ATOM   6540 O O      . ALA   F 1 251 ? 228.816 253.801 217.705 1.00 45.46  ? 263 ALA   A O      1 
ATOM   6541 C CB     . ALA   F 1 251 ? 230.674 251.451 218.483 1.00 40.44  ? 263 ALA   A CB     1 
ATOM   6542 N N      . LEU   F 1 252 ? 229.249 252.779 215.747 1.00 42.96  ? 264 LEU   A N      1 
ATOM   6543 C CA     . LEU   F 1 252 ? 229.000 253.989 214.975 1.00 42.65  ? 264 LEU   A CA     1 
ATOM   6544 C C      . LEU   F 1 252 ? 227.531 254.383 214.996 1.00 43.73  ? 264 LEU   A C      1 
ATOM   6545 O O      . LEU   F 1 252 ? 227.217 255.570 214.867 1.00 48.06  ? 264 LEU   A O      1 
ATOM   6546 C CB     . LEU   F 1 252 ? 229.471 253.800 213.533 1.00 42.20  ? 264 LEU   A CB     1 
ATOM   6547 C CG     . LEU   F 1 252 ? 230.924 253.367 213.334 1.00 39.52  ? 264 LEU   A CG     1 
ATOM   6548 C CD1    . LEU   F 1 252 ? 231.131 252.819 211.936 1.00 42.33  ? 264 LEU   A CD1    1 
ATOM   6549 C CD2    . LEU   F 1 252 ? 231.869 254.521 213.597 1.00 44.17  ? 264 LEU   A CD2    1 
ATOM   6550 N N      . ILE   F 1 253 ? 226.632 253.417 215.158 1.00 40.69  ? 265 ILE   A N      1 
ATOM   6551 C CA     . ILE   F 1 253 ? 225.197 253.671 215.249 1.00 42.82  ? 265 ILE   A CA     1 
ATOM   6552 C C      . ILE   F 1 253 ? 224.720 253.574 216.693 1.00 44.65  ? 265 ILE   A C      1 
ATOM   6553 O O      . ILE   F 1 253 ? 224.062 254.482 217.202 1.00 43.37  ? 265 ILE   A O      1 
ATOM   6554 C CB     . ILE   F 1 253 ? 224.407 252.711 214.334 1.00 44.47  ? 265 ILE   A CB     1 
ATOM   6555 C CG1    . ILE   F 1 253 ? 224.912 252.807 212.895 1.00 45.40  ? 265 ILE   A CG1    1 
ATOM   6556 C CG2    . ILE   F 1 253 ? 222.922 253.016 214.400 1.00 45.04  ? 265 ILE   A CG2    1 
ATOM   6557 C CD1    . ILE   F 1 253 ? 225.301 254.199 212.486 1.00 50.64  ? 265 ILE   A CD1    1 
ATOM   6558 N N      . LEU   F 1 254 ? 225.034 252.467 217.366 1.00 47.01  ? 266 LEU   A N      1 
ATOM   6559 C CA     . LEU   F 1 254 ? 224.730 252.282 218.784 1.00 43.82  ? 266 LEU   A CA     1 
ATOM   6560 C C      . LEU   F 1 254 ? 225.969 252.648 219.603 1.00 42.14  ? 266 LEU   A C      1 
ATOM   6561 O O      . LEU   F 1 254 ? 226.719 251.799 220.087 1.00 43.78  ? 266 LEU   A O      1 
ATOM   6562 C CB     . LEU   F 1 254 ? 224.284 250.851 219.041 1.00 44.60  ? 266 LEU   A CB     1 
ATOM   6563 C CG     . LEU   F 1 254 ? 223.277 250.291 218.037 1.00 45.93  ? 266 LEU   A CG     1 
ATOM   6564 C CD1    . LEU   F 1 254 ? 223.000 248.827 218.316 1.00 54.62  ? 266 LEU   A CD1    1 
ATOM   6565 C CD2    . LEU   F 1 254 ? 221.992 251.092 218.076 1.00 42.36  ? 266 LEU   A CD2    1 
ATOM   6566 N N      . ARG   F 1 255 ? 226.177 253.953 219.747 1.00 43.72  ? 267 ARG   A N      1 
ATOM   6567 C CA     . ARG   F 1 255 ? 227.408 254.450 220.345 1.00 43.95  ? 267 ARG   A CA     1 
ATOM   6568 C C      . ARG   F 1 255 ? 227.498 254.074 221.818 1.00 45.49  ? 267 ARG   A C      1 
ATOM   6569 O O      . ARG   F 1 255 ? 226.490 254.001 222.524 1.00 50.41  ? 267 ARG   A O      1 
ATOM   6570 C CB     . ARG   F 1 255 ? 227.497 255.967 220.185 1.00 42.03  ? 267 ARG   A CB     1 
ATOM   6571 C CG     . ARG   F 1 255 ? 227.351 256.442 218.757 1.00 40.61  ? 267 ARG   A CG     1 
ATOM   6572 C CD     . ARG   F 1 255 ? 227.125 257.936 218.700 1.00 42.23  ? 267 ARG   A CD     1 
ATOM   6573 N NE     . ARG   F 1 255 ? 226.898 258.398 217.338 1.00 41.45  ? 267 ARG   A NE     1 
ATOM   6574 C CZ     . ARG   F 1 255 ? 225.713 258.419 216.746 1.00 43.97  ? 267 ARG   A CZ     1 
ATOM   6575 N NH1    . ARG   F 1 255 ? 224.625 257.998 217.367 1.00 41.37  ? 267 ARG   A NH1    1 
ATOM   6576 N NH2    . ARG   F 1 255 ? 225.616 258.878 215.503 1.00 46.26  ? 267 ARG   A NH2    1 
ATOM   6577 N N      . GLY   F 1 256 ? 228.723 253.833 222.278 1.00 42.09  ? 268 GLY   A N      1 
ATOM   6578 C CA     . GLY   F 1 256 ? 228.966 253.517 223.667 1.00 45.39  ? 268 GLY   A CA     1 
ATOM   6579 C C      . GLY   F 1 256 ? 229.057 254.754 224.537 1.00 53.11  ? 268 GLY   A C      1 
ATOM   6580 O O      . GLY   F 1 256 ? 228.923 255.891 224.088 1.00 58.11  ? 268 GLY   A O      1 
ATOM   6581 N N      . SER   F 1 257 ? 229.302 254.514 225.821 1.00 51.32  ? 269 SER   A N      1 
ATOM   6582 C CA     . SER   F 1 257 ? 229.420 255.575 226.817 1.00 49.17  ? 269 SER   A CA     1 
ATOM   6583 C C      . SER   F 1 257 ? 230.903 255.814 227.075 1.00 49.80  ? 269 SER   A C      1 
ATOM   6584 O O      . SER   F 1 257 ? 231.571 255.004 227.721 1.00 51.38  ? 269 SER   A O      1 
ATOM   6585 C CB     . SER   F 1 257 ? 228.680 255.199 228.095 1.00 47.98  ? 269 SER   A CB     1 
ATOM   6586 O OG     . SER   F 1 257 ? 229.256 254.057 228.700 1.00 51.85  ? 269 SER   A OG     1 
ATOM   6587 N N      . VAL   F 1 258 ? 231.417 256.929 226.566 1.00 47.62  ? 270 VAL   A N      1 
ATOM   6588 C CA     . VAL   F 1 258 ? 232.817 257.301 226.720 1.00 46.52  ? 270 VAL   A CA     1 
ATOM   6589 C C      . VAL   F 1 258 ? 232.872 258.597 227.516 1.00 48.86  ? 270 VAL   A C      1 
ATOM   6590 O O      . VAL   F 1 258 ? 232.245 259.593 227.135 1.00 53.91  ? 270 VAL   A O      1 
ATOM   6591 C CB     . VAL   F 1 258 ? 233.516 257.452 225.361 1.00 42.97  ? 270 VAL   A CB     1 
ATOM   6592 C CG1    . VAL   F 1 258 ? 234.891 258.066 225.539 1.00 46.02  ? 270 VAL   A CG1    1 
ATOM   6593 C CG2    . VAL   F 1 258 ? 233.617 256.106 224.670 1.00 42.49  ? 270 VAL   A CG2    1 
ATOM   6594 N N      . ALA   F 1 259 ? 233.610 258.583 228.621 1.00 46.35  ? 271 ALA   A N      1 
ATOM   6595 C CA     . ALA   F 1 259 ? 233.713 259.766 229.462 1.00 49.80  ? 271 ALA   A CA     1 
ATOM   6596 C C      . ALA   F 1 259 ? 234.550 260.838 228.780 1.00 48.51  ? 271 ALA   A C      1 
ATOM   6597 O O      . ALA   F 1 259 ? 235.587 260.551 228.176 1.00 48.73  ? 271 ALA   A O      1 
ATOM   6598 C CB     . ALA   F 1 259 ? 234.322 259.406 230.816 1.00 53.09  ? 271 ALA   A CB     1 
ATOM   6599 N N      . HIS   F 1 260 ? 234.095 262.084 228.882 1.00 46.67  ? 272 HIS   A N      1 
ATOM   6600 C CA     . HIS   F 1 260 ? 234.778 263.221 228.278 1.00 46.30  ? 272 HIS   A CA     1 
ATOM   6601 C C      . HIS   F 1 260 ? 235.131 264.211 229.376 1.00 48.92  ? 272 HIS   A C      1 
ATOM   6602 O O      . HIS   F 1 260 ? 234.241 264.726 230.059 1.00 48.89  ? 272 HIS   A O      1 
ATOM   6603 C CB     . HIS   F 1 260 ? 233.906 263.887 227.211 1.00 47.02  ? 272 HIS   A CB     1 
ATOM   6604 C CG     . HIS   F 1 260 ? 233.656 263.027 226.013 1.00 48.22  ? 272 HIS   A CG     1 
ATOM   6605 N ND1    . HIS   F 1 260 ? 232.666 262.070 225.979 1.00 45.73  ? 272 HIS   A ND1    1 
ATOM   6606 C CD2    . HIS   F 1 260 ? 234.268 262.978 224.807 1.00 50.12  ? 272 HIS   A CD2    1 
ATOM   6607 C CE1    . HIS   F 1 260 ? 232.678 261.469 224.802 1.00 45.96  ? 272 HIS   A CE1    1 
ATOM   6608 N NE2    . HIS   F 1 260 ? 233.641 262.001 224.073 1.00 45.98  ? 272 HIS   A NE2    1 
ATOM   6609 N N      . LYS   F 1 261 ? 236.423 264.478 229.540 1.00 48.47  ? 273 LYS   A N      1 
ATOM   6610 C CA     . LYS   F 1 261 ? 236.915 265.384 230.566 1.00 46.10  ? 273 LYS   A CA     1 
ATOM   6611 C C      . LYS   F 1 261 ? 237.786 266.453 229.927 1.00 48.56  ? 273 LYS   A C      1 
ATOM   6612 O O      . LYS   F 1 261 ? 238.520 266.178 228.974 1.00 52.30  ? 273 LYS   A O      1 
ATOM   6613 C CB     . LYS   F 1 261 ? 237.712 264.634 231.639 1.00 46.14  ? 273 LYS   A CB     1 
ATOM   6614 C CG     . LYS   F 1 261 ? 236.940 263.525 232.325 1.00 46.35  ? 273 LYS   A CG     1 
ATOM   6615 C CD     . LYS   F 1 261 ? 237.872 262.454 232.861 1.00 44.46  ? 273 LYS   A CD     1 
ATOM   6616 C CE     . LYS   F 1 261 ? 237.135 261.496 233.775 1.00 38.55  ? 273 LYS   A CE     1 
ATOM   6617 N NZ     . LYS   F 1 261 ? 235.990 262.157 234.451 1.00 39.50  ? 273 LYS   A NZ     1 
ATOM   6618 N N      . SER   F 1 262 ? 237.698 267.671 230.453 1.00 47.48  ? 274 SER   A N      1 
ATOM   6619 C CA     . SER   F 1 262 ? 238.464 268.809 229.946 1.00 46.40  ? 274 SER   A CA     1 
ATOM   6620 C C      . SER   F 1 262 ? 239.756 268.910 230.751 1.00 47.02  ? 274 SER   A C      1 
ATOM   6621 O O      . SER   F 1 262 ? 239.788 269.468 231.847 1.00 48.08  ? 274 SER   A O      1 
ATOM   6622 C CB     . SER   F 1 262 ? 237.648 270.092 230.025 1.00 45.28  ? 274 SER   A CB     1 
ATOM   6623 O OG     . SER   F 1 262 ? 236.300 269.858 229.668 1.00 50.25  ? 274 SER   A OG     1 
ATOM   6624 N N      . CYS   F 1 263 ? 240.830 268.362 230.194 1.00 47.12  ? 275 CYS   A N      1 
ATOM   6625 C CA     . CYS   F 1 263 ? 242.150 268.415 230.807 1.00 44.88  ? 275 CYS   A CA     1 
ATOM   6626 C C      . CYS   F 1 263 ? 242.938 269.539 230.144 1.00 46.99  ? 275 CYS   A C      1 
ATOM   6627 O O      . CYS   F 1 263 ? 243.315 269.434 228.973 1.00 47.31  ? 275 CYS   A O      1 
ATOM   6628 C CB     . CYS   F 1 263 ? 242.866 267.075 230.668 1.00 44.14  ? 275 CYS   A CB     1 
ATOM   6629 S SG     . CYS   F 1 263 ? 241.981 265.694 231.414 1.00 54.49  ? 275 CYS   A SG     1 
ATOM   6630 N N      . LEU   F 1 264 ? 243.174 270.610 230.889 1.00 46.76  ? 276 LEU   A N      1 
ATOM   6631 C CA     . LEU   F 1 264 ? 243.851 271.781 230.363 1.00 47.89  ? 276 LEU   A CA     1 
ATOM   6632 C C      . LEU   F 1 264 ? 245.364 271.626 230.455 1.00 47.22  ? 276 LEU   A C      1 
ATOM   6633 O O      . LEU   F 1 264 ? 245.871 270.797 231.214 1.00 45.40  ? 276 LEU   A O      1 
ATOM   6634 C CB     . LEU   F 1 264 ? 243.410 273.024 231.125 1.00 46.48  ? 276 LEU   A CB     1 
ATOM   6635 C CG     . LEU   F 1 264 ? 241.915 273.334 231.101 1.00 44.54  ? 276 LEU   A CG     1 
ATOM   6636 C CD1    . LEU   F 1 264 ? 241.648 274.692 231.721 1.00 45.96  ? 276 LEU   A CD1    1 
ATOM   6637 C CD2    . LEU   F 1 264 ? 241.384 273.274 229.683 1.00 47.67  ? 276 LEU   A CD2    1 
ATOM   6638 N N      . PRO   F 1 265 ? 246.111 272.411 229.685 1.00 48.60  ? 277 PRO   A N      1 
ATOM   6639 C CA     . PRO   F 1 265 ? 247.571 272.385 229.811 1.00 43.28  ? 277 PRO   A CA     1 
ATOM   6640 C C      . PRO   F 1 265 ? 248.014 272.910 231.166 1.00 45.94  ? 277 PRO   A C      1 
ATOM   6641 O O      . PRO   F 1 265 ? 247.332 273.717 231.802 1.00 46.43  ? 277 PRO   A O      1 
ATOM   6642 C CB     . PRO   F 1 265 ? 248.043 273.298 228.675 1.00 44.60  ? 277 PRO   A CB     1 
ATOM   6643 C CG     . PRO   F 1 265 ? 246.875 274.181 228.392 1.00 41.05  ? 277 PRO   A CG     1 
ATOM   6644 C CD     . PRO   F 1 265 ? 245.667 273.331 228.625 1.00 47.79  ? 277 PRO   A CD     1 
ATOM   6645 N N      . ALA   F 1 266 ? 249.179 272.434 231.608 1.00 45.84  ? 278 ALA   A N      1 
ATOM   6646 C CA     . ALA   F 1 266 ? 249.674 272.793 232.931 1.00 43.68  ? 278 ALA   A CA     1 
ATOM   6647 C C      . ALA   F 1 266 ? 249.955 274.283 233.063 1.00 44.00  ? 278 ALA   A C      1 
ATOM   6648 O O      . ALA   F 1 266 ? 249.998 274.797 234.185 1.00 45.13  ? 278 ALA   A O      1 
ATOM   6649 C CB     . ALA   F 1 266 ? 250.935 271.992 233.256 1.00 40.52  ? 278 ALA   A CB     1 
ATOM   6650 N N      . CYS   F 1 267 ? 250.147 274.990 231.948 1.00 45.38  ? 279 CYS   A N      1 
ATOM   6651 C CA     . CYS   F 1 267 ? 250.388 276.427 232.025 1.00 45.04  ? 279 CYS   A CA     1 
ATOM   6652 C C      . CYS   F 1 267 ? 249.185 277.154 232.609 1.00 43.90  ? 279 CYS   A C      1 
ATOM   6653 O O      . CYS   F 1 267 ? 249.340 278.106 233.383 1.00 44.88  ? 279 CYS   A O      1 
ATOM   6654 C CB     . CYS   F 1 267 ? 250.737 276.978 230.642 1.00 44.22  ? 279 CYS   A CB     1 
ATOM   6655 S SG     . CYS   F 1 267 ? 249.861 276.196 229.274 1.00 61.88  ? 279 CYS   A SG     1 
ATOM   6656 N N      . VAL   F 1 268 ? 247.976 276.723 232.247 1.00 43.65  ? 280 VAL   A N      1 
ATOM   6657 C CA     . VAL   F 1 268 ? 246.768 277.359 232.764 1.00 44.28  ? 280 VAL   A CA     1 
ATOM   6658 C C      . VAL   F 1 268 ? 246.664 277.159 234.271 1.00 45.00  ? 280 VAL   A C      1 
ATOM   6659 O O      . VAL   F 1 268 ? 246.315 278.083 235.016 1.00 43.07  ? 280 VAL   A O      1 
ATOM   6660 C CB     . VAL   F 1 268 ? 245.526 276.818 232.034 1.00 45.60  ? 280 VAL   A CB     1 
ATOM   6661 C CG1    . VAL   F 1 268 ? 244.273 277.509 232.535 1.00 49.47  ? 280 VAL   A CG1    1 
ATOM   6662 C CG2    . VAL   F 1 268 ? 245.679 276.995 230.535 1.00 44.26  ? 280 VAL   A CG2    1 
ATOM   6663 N N      . TYR   F 1 269 ? 246.948 275.943 234.742 1.00 48.24  ? 281 TYR   A N      1 
ATOM   6664 C CA     . TYR   F 1 269 ? 246.908 275.681 236.177 1.00 44.19  ? 281 TYR   A CA     1 
ATOM   6665 C C      . TYR   F 1 269 ? 247.982 276.468 236.916 1.00 41.81  ? 281 TYR   A C      1 
ATOM   6666 O O      . TYR   F 1 269 ? 247.733 277.000 238.003 1.00 40.10  ? 281 TYR   A O      1 
ATOM   6667 C CB     . TYR   F 1 269 ? 247.058 274.184 236.447 1.00 43.68  ? 281 TYR   A CB     1 
ATOM   6668 C CG     . TYR   F 1 269 ? 246.009 273.325 235.783 1.00 45.92  ? 281 TYR   A CG     1 
ATOM   6669 C CD1    . TYR   F 1 269 ? 244.671 273.688 235.808 1.00 45.57  ? 281 TYR   A CD1    1 
ATOM   6670 C CD2    . TYR   F 1 269 ? 246.354 272.147 235.138 1.00 46.98  ? 281 TYR   A CD2    1 
ATOM   6671 C CE1    . TYR   F 1 269 ? 243.709 272.904 235.207 1.00 46.91  ? 281 TYR   A CE1    1 
ATOM   6672 C CE2    . TYR   F 1 269 ? 245.398 271.357 234.535 1.00 45.39  ? 281 TYR   A CE2    1 
ATOM   6673 C CZ     . TYR   F 1 269 ? 244.078 271.740 234.573 1.00 44.80  ? 281 TYR   A CZ     1 
ATOM   6674 O OH     . TYR   F 1 269 ? 243.124 270.957 233.973 1.00 46.18  ? 281 TYR   A OH     1 
ATOM   6675 N N      . GLY   F 1 270 ? 249.185 276.548 236.348 1.00 43.03  ? 282 GLY   A N      1 
ATOM   6676 C CA     . GLY   F 1 270 ? 250.237 277.315 236.991 1.00 44.19  ? 282 GLY   A CA     1 
ATOM   6677 C C      . GLY   F 1 270 ? 249.886 278.784 237.118 1.00 46.53  ? 282 GLY   A C      1 
ATOM   6678 O O      . GLY   F 1 270 ? 250.134 279.405 238.154 1.00 48.83  ? 282 GLY   A O      1 
ATOM   6679 N N      . SER   F 1 271 ? 249.298 279.359 236.068 1.00 44.86  ? 283 SER   A N      1 
ATOM   6680 C CA     . SER   F 1 271 ? 248.870 280.751 236.132 1.00 43.53  ? 283 SER   A CA     1 
ATOM   6681 C C      . SER   F 1 271 ? 247.799 280.950 237.197 1.00 45.53  ? 283 SER   A C      1 
ATOM   6682 O O      . SER   F 1 271 ? 247.840 281.924 237.956 1.00 48.87  ? 283 SER   A O      1 
ATOM   6683 C CB     . SER   F 1 271 ? 248.362 281.202 234.764 1.00 46.18  ? 283 SER   A CB     1 
ATOM   6684 O OG     . SER   F 1 271 ? 247.616 282.400 234.867 1.00 53.54  ? 283 SER   A OG     1 
ATOM   6685 N N      . ALA   F 1 272 ? 246.833 280.031 237.271 1.00 44.14  ? 284 ALA   A N      1 
ATOM   6686 C CA     . ALA   F 1 272 ? 245.749 280.171 238.239 1.00 42.62  ? 284 ALA   A CA     1 
ATOM   6687 C C      . ALA   F 1 272 ? 246.260 280.067 239.671 1.00 43.22  ? 284 ALA   A C      1 
ATOM   6688 O O      . ALA   F 1 272 ? 245.849 280.842 240.542 1.00 43.60  ? 284 ALA   A O      1 
ATOM   6689 C CB     . ALA   F 1 272 ? 244.673 279.119 237.978 1.00 41.62  ? 284 ALA   A CB     1 
ATOM   6690 N N      . VAL   F 1 273 ? 247.153 279.113 239.937 1.00 43.49  ? 285 VAL   A N      1 
ATOM   6691 C CA     . VAL   F 1 273 ? 247.672 278.954 241.291 1.00 44.04  ? 285 VAL   A CA     1 
ATOM   6692 C C      . VAL   F 1 273 ? 248.497 280.169 241.692 1.00 45.58  ? 285 VAL   A C      1 
ATOM   6693 O O      . VAL   F 1 273 ? 248.448 280.617 242.843 1.00 46.68  ? 285 VAL   A O      1 
ATOM   6694 C CB     . VAL   F 1 273 ? 248.484 277.652 241.405 1.00 43.89  ? 285 VAL   A CB     1 
ATOM   6695 C CG1    . VAL   F 1 273 ? 249.243 277.620 242.717 1.00 43.72  ? 285 VAL   A CG1    1 
ATOM   6696 C CG2    . VAL   F 1 273 ? 247.570 276.448 241.287 1.00 43.74  ? 285 VAL   A CG2    1 
ATOM   6697 N N      . ALA   F 1 274 ? 249.267 280.722 240.753 1.00 45.45  ? 286 ALA   A N      1 
ATOM   6698 C CA     . ALA   F 1 274 ? 250.034 281.926 241.050 1.00 45.16  ? 286 ALA   A CA     1 
ATOM   6699 C C      . ALA   F 1 274 ? 249.120 283.106 241.350 1.00 46.70  ? 286 ALA   A C      1 
ATOM   6700 O O      . ALA   F 1 274 ? 249.510 284.023 242.081 1.00 46.27  ? 286 ALA   A O      1 
ATOM   6701 C CB     . ALA   F 1 274 ? 250.970 282.252 239.888 1.00 43.17  ? 286 ALA   A CB     1 
ATOM   6702 N N      . SER   F 1 275 ? 247.906 283.099 240.806 1.00 47.04  ? 287 SER   A N      1 
ATOM   6703 C CA     . SER   F 1 275 ? 246.926 284.142 241.079 1.00 44.64  ? 287 SER   A CA     1 
ATOM   6704 C C      . SER   F 1 275 ? 246.306 284.020 242.463 1.00 48.34  ? 287 SER   A C      1 
ATOM   6705 O O      . SER   F 1 275 ? 245.523 284.891 242.852 1.00 48.21  ? 287 SER   A O      1 
ATOM   6706 C CB     . SER   F 1 275 ? 245.822 284.117 240.020 1.00 42.23  ? 287 SER   A CB     1 
ATOM   6707 O OG     . SER   F 1 275 ? 246.303 284.587 238.775 1.00 49.38  ? 287 SER   A OG     1 
ATOM   6708 N N      . GLY   F 1 276 ? 246.634 282.971 243.209 1.00 51.14  ? 288 GLY   A N      1 
ATOM   6709 C CA     . GLY   F 1 276 ? 246.089 282.761 244.531 1.00 47.40  ? 288 GLY   A CA     1 
ATOM   6710 C C      . GLY   F 1 276 ? 244.882 281.855 244.587 1.00 50.87  ? 288 GLY   A C      1 
ATOM   6711 O O      . GLY   F 1 276 ? 244.384 281.589 245.687 1.00 58.70  ? 288 GLY   A O      1 
ATOM   6712 N N      . TYR   F 1 277 ? 244.398 281.373 243.447 1.00 48.02  ? 289 TYR   A N      1 
ATOM   6713 C CA     . TYR   F 1 277 ? 243.240 280.494 243.449 1.00 45.19  ? 289 TYR   A CA     1 
ATOM   6714 C C      . TYR   F 1 277 ? 243.538 279.220 244.226 1.00 48.87  ? 289 TYR   A C      1 
ATOM   6715 O O      . TYR   F 1 277 ? 244.552 278.554 244.002 1.00 48.87  ? 289 TYR   A O      1 
ATOM   6716 C CB     . TYR   F 1 277 ? 242.826 280.153 242.019 1.00 42.82  ? 289 TYR   A CB     1 
ATOM   6717 C CG     . TYR   F 1 277 ? 241.366 279.796 241.880 1.00 47.81  ? 289 TYR   A CG     1 
ATOM   6718 C CD1    . TYR   F 1 277 ? 240.977 278.487 241.637 1.00 50.62  ? 289 TYR   A CD1    1 
ATOM   6719 C CD2    . TYR   F 1 277 ? 240.377 280.759 242.000 1.00 47.75  ? 289 TYR   A CD2    1 
ATOM   6720 C CE1    . TYR   F 1 277 ? 239.648 278.148 241.512 1.00 45.24  ? 289 TYR   A CE1    1 
ATOM   6721 C CE2    . TYR   F 1 277 ? 239.043 280.428 241.878 1.00 47.82  ? 289 TYR   A CE2    1 
ATOM   6722 C CZ     . TYR   F 1 277 ? 238.686 279.120 241.634 1.00 46.09  ? 289 TYR   A CZ     1 
ATOM   6723 O OH     . TYR   F 1 277 ? 237.361 278.779 241.510 1.00 52.52  ? 289 TYR   A OH     1 
ATOM   6724 N N      . ASP   F 1 278 ? 242.640 278.882 245.140 1.00 49.53  ? 290 ASP   A N      1 
ATOM   6725 C CA     . ASP   F 1 278 ? 242.745 277.680 245.959 1.00 51.26  ? 290 ASP   A CA     1 
ATOM   6726 C C      . ASP   F 1 278 ? 241.721 276.684 245.433 1.00 51.66  ? 290 ASP   A C      1 
ATOM   6727 O O      . ASP   F 1 278 ? 240.549 276.723 245.814 1.00 56.79  ? 290 ASP   A O      1 
ATOM   6728 C CB     . ASP   F 1 278 ? 242.511 277.998 247.432 1.00 52.34  ? 290 ASP   A CB     1 
ATOM   6729 C CG     . ASP   F 1 278 ? 243.210 277.024 248.354 1.00 52.77  ? 290 ASP   A CG     1 
ATOM   6730 O OD1    . ASP   F 1 278 ? 243.001 275.805 248.200 1.00 52.76  ? 290 ASP   A OD1    1 
ATOM   6731 O OD2    . ASP   F 1 278 ? 243.967 277.478 249.235 1.00 58.36  ? 290 ASP   A OD2    1 
ATOM   6732 N N      . PHE   F 1 279 ? 242.167 275.793 244.548 1.00 47.09  ? 291 PHE   A N      1 
ATOM   6733 C CA     . PHE   F 1 279 ? 241.260 274.789 244.010 1.00 48.41  ? 291 PHE   A CA     1 
ATOM   6734 C C      . PHE   F 1 279 ? 240.761 273.856 245.102 1.00 51.38  ? 291 PHE   A C      1 
ATOM   6735 O O      . PHE   F 1 279 ? 239.622 273.383 245.041 1.00 56.78  ? 291 PHE   A O      1 
ATOM   6736 C CB     . PHE   F 1 279 ? 241.951 273.993 242.906 1.00 47.65  ? 291 PHE   A CB     1 
ATOM   6737 C CG     . PHE   F 1 279 ? 242.308 274.810 241.700 1.00 44.63  ? 291 PHE   A CG     1 
ATOM   6738 C CD1    . PHE   F 1 279 ? 241.366 275.077 240.724 1.00 45.84  ? 291 PHE   A CD1    1 
ATOM   6739 C CD2    . PHE   F 1 279 ? 243.591 275.296 241.533 1.00 44.83  ? 291 PHE   A CD2    1 
ATOM   6740 C CE1    . PHE   F 1 279 ? 241.695 275.825 239.614 1.00 46.23  ? 291 PHE   A CE1    1 
ATOM   6741 C CE2    . PHE   F 1 279 ? 243.926 276.041 240.422 1.00 43.23  ? 291 PHE   A CE2    1 
ATOM   6742 C CZ     . PHE   F 1 279 ? 242.976 276.306 239.462 1.00 44.22  ? 291 PHE   A CZ     1 
ATOM   6743 N N      . GLU   F 1 280 ? 241.597 273.580 246.102 1.00 50.76  ? 292 GLU   A N      1 
ATOM   6744 C CA     . GLU   F 1 280 ? 241.184 272.714 247.200 1.00 51.87  ? 292 GLU   A CA     1 
ATOM   6745 C C      . GLU   F 1 280 ? 240.024 273.326 247.976 1.00 51.99  ? 292 GLU   A C      1 
ATOM   6746 O O      . GLU   F 1 280 ? 239.084 272.622 248.359 1.00 55.60  ? 292 GLU   A O      1 
ATOM   6747 C CB     . GLU   F 1 280 ? 242.375 272.446 248.119 1.00 52.07  ? 292 GLU   A CB     1 
ATOM   6748 C CG     . GLU   F 1 280 ? 242.012 271.912 249.486 1.00 53.64  ? 292 GLU   A CG     1 
ATOM   6749 C CD     . GLU   F 1 280 ? 241.866 270.408 249.498 1.00 59.67  ? 292 GLU   A CD     1 
ATOM   6750 O OE1    . GLU   F 1 280 ? 241.658 269.823 248.416 1.00 60.95  ? 292 GLU   A OE1    1 
ATOM   6751 O OE2    . GLU   F 1 280 ? 241.965 269.809 250.588 1.00 67.45  ? 292 GLU   A OE2    1 
ATOM   6752 N N      . ARG   F 1 281 ? 240.072 274.636 248.217 1.00 52.66  ? 293 ARG   A N      1 
ATOM   6753 C CA     . ARG   F 1 281 ? 238.992 275.301 248.937 1.00 56.56  ? 293 ARG   A CA     1 
ATOM   6754 C C      . ARG   F 1 281 ? 237.761 275.457 248.054 1.00 56.27  ? 293 ARG   A C      1 
ATOM   6755 O O      . ARG   F 1 281 ? 236.653 275.060 248.432 1.00 64.03  ? 293 ARG   A O      1 
ATOM   6756 C CB     . ARG   F 1 281 ? 239.464 276.662 249.448 1.00 61.22  ? 293 ARG   A CB     1 
ATOM   6757 C CG     . ARG   F 1 281 ? 240.206 276.607 250.768 1.00 72.84  ? 293 ARG   A CG     1 
ATOM   6758 C CD     . ARG   F 1 281 ? 240.769 277.967 251.130 1.00 74.86  ? 293 ARG   A CD     1 
ATOM   6759 N NE     . ARG   F 1 281 ? 239.975 279.048 250.561 1.00 74.34  ? 293 ARG   A NE     1 
ATOM   6760 C CZ     . ARG   F 1 281 ? 238.814 279.459 251.048 1.00 87.75  ? 293 ARG   A CZ     1 
ATOM   6761 N NH1    . ARG   F 1 281 ? 238.275 278.898 252.118 1.00 87.46  ? 293 ARG   A NH1    1 
ATOM   6762 N NH2    . ARG   F 1 281 ? 238.176 280.459 250.447 1.00 97.27  ? 293 ARG   A NH2    1 
ATOM   6763 N N      . GLU   F 1 282 ? 237.937 276.039 246.869 1.00 51.82  ? 294 GLU   A N      1 
ATOM   6764 C CA     . GLU   F 1 282 ? 236.802 276.298 245.994 1.00 51.45  ? 294 GLU   A CA     1 
ATOM   6765 C C      . GLU   F 1 282 ? 236.335 275.051 245.255 1.00 52.60  ? 294 GLU   A C      1 
ATOM   6766 O O      . GLU   F 1 282 ? 235.184 275.007 244.808 1.00 51.53  ? 294 GLU   A O      1 
ATOM   6767 C CB     . GLU   F 1 282 ? 237.161 277.397 244.997 1.00 51.45  ? 294 GLU   A CB     1 
ATOM   6768 C CG     . GLU   F 1 282 ? 237.321 278.762 245.638 1.00 52.56  ? 294 GLU   A CG     1 
ATOM   6769 C CD     . GLU   F 1 282 ? 236.390 279.796 245.050 1.00 63.51  ? 294 GLU   A CD     1 
ATOM   6770 O OE1    . GLU   F 1 282 ? 235.688 279.476 244.070 1.00 69.83  ? 294 GLU   A OE1    1 
ATOM   6771 O OE2    . GLU   F 1 282 ? 236.360 280.929 245.570 1.00 66.83  ? 294 GLU   A OE2    1 
ATOM   6772 N N      . GLY   F 1 283 ? 237.188 274.041 245.123 1.00 52.49  ? 295 GLY   A N      1 
ATOM   6773 C CA     . GLY   F 1 283 ? 236.831 272.823 244.431 1.00 46.94  ? 295 GLY   A CA     1 
ATOM   6774 C C      . GLY   F 1 283 ? 236.959 272.947 242.924 1.00 48.10  ? 295 GLY   A C      1 
ATOM   6775 O O      . GLY   F 1 283 ? 237.039 274.034 242.352 1.00 50.08  ? 295 GLY   A O      1 
ATOM   6776 N N      . TYR   F 1 284 ? 236.965 271.790 242.268 1.00 47.84  ? 296 TYR   A N      1 
ATOM   6777 C CA     . TYR   F 1 284 ? 237.131 271.716 240.825 1.00 45.52  ? 296 TYR   A CA     1 
ATOM   6778 C C      . TYR   F 1 284 ? 236.314 270.553 240.282 1.00 49.29  ? 296 TYR   A C      1 
ATOM   6779 O O      . TYR   F 1 284 ? 235.856 269.682 241.025 1.00 53.82  ? 296 TYR   A O      1 
ATOM   6780 C CB     . TYR   F 1 284 ? 238.607 271.561 240.445 1.00 43.97  ? 296 TYR   A CB     1 
ATOM   6781 C CG     . TYR   F 1 284 ? 238.939 271.981 239.033 1.00 44.70  ? 296 TYR   A CG     1 
ATOM   6782 C CD1    . TYR   F 1 284 ? 238.959 273.319 238.669 1.00 43.50  ? 296 TYR   A CD1    1 
ATOM   6783 C CD2    . TYR   F 1 284 ? 239.240 271.035 238.065 1.00 49.21  ? 296 TYR   A CD2    1 
ATOM   6784 C CE1    . TYR   F 1 284 ? 239.267 273.701 237.378 1.00 46.28  ? 296 TYR   A CE1    1 
ATOM   6785 C CE2    . TYR   F 1 284 ? 239.549 271.406 236.775 1.00 48.22  ? 296 TYR   A CE2    1 
ATOM   6786 C CZ     . TYR   F 1 284 ? 239.562 272.738 236.437 1.00 47.93  ? 296 TYR   A CZ     1 
ATOM   6787 O OH     . TYR   F 1 284 ? 239.871 273.104 235.149 1.00 49.91  ? 296 TYR   A OH     1 
ATOM   6788 N N      . SER   F 1 285 ? 236.142 270.545 238.962 1.00 49.57  ? 297 SER   A N      1 
ATOM   6789 C CA     . SER   F 1 285 ? 235.407 269.488 238.283 1.00 46.96  ? 297 SER   A CA     1 
ATOM   6790 C C      . SER   F 1 285 ? 235.760 269.478 236.803 1.00 48.98  ? 297 SER   A C      1 
ATOM   6791 O O      . SER   F 1 285 ? 235.782 270.530 236.157 1.00 51.31  ? 297 SER   A O      1 
ATOM   6792 C CB     . SER   F 1 285 ? 233.901 269.667 238.473 1.00 45.01  ? 297 SER   A CB     1 
ATOM   6793 O OG     . SER   F 1 285 ? 233.464 270.893 237.917 1.00 53.28  ? 297 SER   A OG     1 
ATOM   6794 N N      . LEU   F 1 286 ? 236.040 268.297 236.257 1.00 48.72  ? 298 LEU   A N      1 
ATOM   6795 C CA     . LEU   F 1 286 ? 236.461 268.188 234.868 1.00 48.96  ? 298 LEU   A CA     1 
ATOM   6796 C C      . LEU   F 1 286 ? 235.294 268.109 233.894 1.00 49.22  ? 298 LEU   A C      1 
ATOM   6797 O O      . LEU   F 1 286 ? 235.525 268.060 232.683 1.00 48.66  ? 298 LEU   A O      1 
ATOM   6798 C CB     . LEU   F 1 286 ? 237.362 266.966 234.691 1.00 47.88  ? 298 LEU   A CB     1 
ATOM   6799 C CG     . LEU   F 1 286 ? 238.531 266.870 235.671 1.00 45.79  ? 298 LEU   A CG     1 
ATOM   6800 C CD1    . LEU   F 1 286 ? 239.454 265.727 235.292 1.00 49.17  ? 298 LEU   A CD1    1 
ATOM   6801 C CD2    . LEU   F 1 286 ? 239.288 268.181 235.732 1.00 46.94  ? 298 LEU   A CD2    1 
ATOM   6802 N N      . VAL   F 1 287 ? 234.057 268.095 234.386 1.00 48.39  ? 299 VAL   A N      1 
ATOM   6803 C CA     . VAL   F 1 287 ? 232.876 268.018 233.538 1.00 47.60  ? 299 VAL   A CA     1 
ATOM   6804 C C      . VAL   F 1 287 ? 231.947 269.208 233.713 1.00 46.41  ? 299 VAL   A C      1 
ATOM   6805 O O      . VAL   F 1 287 ? 230.945 269.303 233.000 1.00 44.33  ? 299 VAL   A O      1 
ATOM   6806 C CB     . VAL   F 1 287 ? 232.103 266.704 233.775 1.00 46.44  ? 299 VAL   A CB     1 
ATOM   6807 C CG1    . VAL   F 1 287 ? 233.004 265.512 233.522 1.00 47.71  ? 299 VAL   A CG1    1 
ATOM   6808 C CG2    . VAL   F 1 287 ? 231.554 266.665 235.187 1.00 48.40  ? 299 VAL   A CG2    1 
ATOM   6809 N N      . GLY   F 1 288 ? 232.250 270.122 234.630 1.00 47.84  ? 300 GLY   A N      1 
ATOM   6810 C CA     . GLY   F 1 288 ? 231.397 271.250 234.923 1.00 46.25  ? 300 GLY   A CA     1 
ATOM   6811 C C      . GLY   F 1 288 ? 231.884 272.539 234.295 1.00 46.88  ? 300 GLY   A C      1 
ATOM   6812 O O      . GLY   F 1 288 ? 232.556 272.548 233.257 1.00 52.03  ? 300 GLY   A O      1 
ATOM   6813 N N      . ILE   F 1 289 ? 231.529 273.656 234.938 1.00 47.01  ? 301 ILE   A N      1 
ATOM   6814 C CA     . ILE   F 1 289 ? 231.899 274.977 234.435 1.00 47.56  ? 301 ILE   A CA     1 
ATOM   6815 C C      . ILE   F 1 289 ? 233.319 275.383 234.788 1.00 46.69  ? 301 ILE   A C      1 
ATOM   6816 O O      . ILE   F 1 289 ? 233.857 276.309 234.168 1.00 45.90  ? 301 ILE   A O      1 
ATOM   6817 C CB     . ILE   F 1 289 ? 230.938 276.056 234.968 1.00 45.22  ? 301 ILE   A CB     1 
ATOM   6818 C CG1    . ILE   F 1 289 ? 231.108 277.357 234.185 1.00 44.23  ? 301 ILE   A CG1    1 
ATOM   6819 C CG2    . ILE   F 1 289 ? 231.166 276.290 236.448 1.00 44.79  ? 301 ILE   A CG2    1 
ATOM   6820 C CD1    . ILE   F 1 289 ? 230.227 278.478 234.676 1.00 50.88  ? 301 ILE   A CD1    1 
ATOM   6821 N N      . ASP   F 1 290 ? 233.943 274.720 235.757 1.00 47.99  ? 302 ASP   A N      1 
ATOM   6822 C CA     . ASP   F 1 290 ? 235.258 275.157 236.219 1.00 45.87  ? 302 ASP   A CA     1 
ATOM   6823 C C      . ASP   F 1 290 ? 236.289 275.203 235.102 1.00 45.59  ? 302 ASP   A C      1 
ATOM   6824 O O      . ASP   F 1 290 ? 237.011 276.210 235.000 1.00 48.43  ? 302 ASP   A O      1 
ATOM   6825 C CB     . ASP   F 1 290 ? 235.716 274.262 237.373 1.00 47.80  ? 302 ASP   A CB     1 
ATOM   6826 C CG     . ASP   F 1 290 ? 234.765 274.305 238.549 1.00 49.43  ? 302 ASP   A CG     1 
ATOM   6827 O OD1    . ASP   F 1 290 ? 233.725 273.618 238.502 1.00 52.00  ? 302 ASP   A OD1    1 
ATOM   6828 O OD2    . ASP   F 1 290 ? 235.052 275.033 239.520 1.00 52.33  ? 302 ASP   A OD2    1 
ATOM   6829 N N      . PRO   F 1 291 ? 236.425 274.186 234.247 1.00 45.01  ? 303 PRO   A N      1 
ATOM   6830 C CA     . PRO   F 1 291 ? 237.378 274.316 233.131 1.00 45.35  ? 303 PRO   A CA     1 
ATOM   6831 C C      . PRO   F 1 291 ? 237.065 275.487 232.217 1.00 45.82  ? 303 PRO   A C      1 
ATOM   6832 O O      . PRO   F 1 291 ? 237.985 276.157 231.732 1.00 44.24  ? 303 PRO   A O      1 
ATOM   6833 C CB     . PRO   F 1 291 ? 237.252 272.969 232.404 1.00 46.07  ? 303 PRO   A CB     1 
ATOM   6834 C CG     . PRO   F 1 291 ? 236.619 272.046 233.393 1.00 46.44  ? 303 PRO   A CG     1 
ATOM   6835 C CD     . PRO   F 1 291 ? 235.715 272.899 234.216 1.00 47.74  ? 303 PRO   A CD     1 
ATOM   6836 N N      . PHE   F 1 292 ? 235.781 275.759 231.978 1.00 46.90  ? 304 PHE   A N      1 
ATOM   6837 C CA     . PHE   F 1 292 ? 235.403 276.863 231.102 1.00 45.40  ? 304 PHE   A CA     1 
ATOM   6838 C C      . PHE   F 1 292 ? 235.736 278.209 231.730 1.00 45.45  ? 304 PHE   A C      1 
ATOM   6839 O O      . PHE   F 1 292 ? 236.246 279.109 231.053 1.00 42.77  ? 304 PHE   A O      1 
ATOM   6840 C CB     . PHE   F 1 292 ? 233.913 276.781 230.779 1.00 44.13  ? 304 PHE   A CB     1 
ATOM   6841 C CG     . PHE   F 1 292 ? 233.598 275.944 229.578 1.00 45.47  ? 304 PHE   A CG     1 
ATOM   6842 C CD1    . PHE   F 1 292 ? 233.923 276.382 228.309 1.00 50.17  ? 304 PHE   A CD1    1 
ATOM   6843 C CD2    . PHE   F 1 292 ? 232.978 274.718 229.717 1.00 45.57  ? 304 PHE   A CD2    1 
ATOM   6844 C CE1    . PHE   F 1 292 ? 233.632 275.614 227.202 1.00 49.93  ? 304 PHE   A CE1    1 
ATOM   6845 C CE2    . PHE   F 1 292 ? 232.686 273.947 228.613 1.00 46.08  ? 304 PHE   A CE2    1 
ATOM   6846 C CZ     . PHE   F 1 292 ? 233.013 274.395 227.355 1.00 44.10  ? 304 PHE   A CZ     1 
ATOM   6847 N N      . ARG   F 1 293 ? 235.445 278.366 233.022 1.00 47.90  ? 305 ARG   A N      1 
ATOM   6848 C CA     . ARG   F 1 293 ? 235.710 279.629 233.700 1.00 48.60  ? 305 ARG   A CA     1 
ATOM   6849 C C      . ARG   F 1 293 ? 237.203 279.866 233.876 1.00 48.17  ? 305 ARG   A C      1 
ATOM   6850 O O      . ARG   F 1 293 ? 237.650 281.017 233.898 1.00 49.73  ? 305 ARG   A O      1 
ATOM   6851 C CB     . ARG   F 1 293 ? 234.981 279.647 235.045 1.00 46.12  ? 305 ARG   A CB     1 
ATOM   6852 C CG     . ARG   F 1 293 ? 235.052 280.957 235.795 1.00 46.62  ? 305 ARG   A CG     1 
ATOM   6853 C CD     . ARG   F 1 293 ? 235.550 280.743 237.213 1.00 54.13  ? 305 ARG   A CD     1 
ATOM   6854 N NE     . ARG   F 1 293 ? 235.093 279.475 237.768 1.00 53.29  ? 305 ARG   A NE     1 
ATOM   6855 C CZ     . ARG   F 1 293 ? 233.834 279.208 238.089 1.00 48.71  ? 305 ARG   A CZ     1 
ATOM   6856 N NH1    . ARG   F 1 293 ? 232.874 280.101 237.922 1.00 47.26  ? 305 ARG   A NH1    1 
ATOM   6857 N NH2    . ARG   F 1 293 ? 233.532 278.016 238.594 1.00 51.32  ? 305 ARG   A NH2    1 
ATOM   6858 N N      . LEU   F 1 294 ? 237.986 278.794 234.000 1.00 49.19  ? 306 LEU   A N      1 
ATOM   6859 C CA     . LEU   F 1 294 ? 239.436 278.936 234.056 1.00 48.23  ? 306 LEU   A CA     1 
ATOM   6860 C C      . LEU   F 1 294 ? 240.000 279.387 232.714 1.00 48.41  ? 306 LEU   A C      1 
ATOM   6861 O O      . LEU   F 1 294 ? 240.897 280.236 232.662 1.00 48.33  ? 306 LEU   A O      1 
ATOM   6862 C CB     . LEU   F 1 294 ? 240.068 277.614 234.490 1.00 45.36  ? 306 LEU   A CB     1 
ATOM   6863 C CG     . LEU   F 1 294 ? 241.517 277.651 234.969 1.00 47.34  ? 306 LEU   A CG     1 
ATOM   6864 C CD1    . LEU   F 1 294 ? 241.647 278.520 236.205 1.00 49.13  ? 306 LEU   A CD1    1 
ATOM   6865 C CD2    . LEU   F 1 294 ? 242.015 276.245 235.243 1.00 46.72  ? 306 LEU   A CD2    1 
ATOM   6866 N N      . LEU   F 1 295 ? 239.489 278.825 231.616 1.00 48.88  ? 307 LEU   A N      1 
ATOM   6867 C CA     . LEU   F 1 295 ? 240.007 279.164 230.295 1.00 48.36  ? 307 LEU   A CA     1 
ATOM   6868 C C      . LEU   F 1 295 ? 239.637 280.583 229.887 1.00 50.18  ? 307 LEU   A C      1 
ATOM   6869 O O      . LEU   F 1 295 ? 240.378 281.221 229.131 1.00 48.22  ? 307 LEU   A O      1 
ATOM   6870 C CB     . LEU   F 1 295 ? 239.496 278.166 229.258 1.00 44.55  ? 307 LEU   A CB     1 
ATOM   6871 C CG     . LEU   F 1 295 ? 240.345 276.911 229.059 1.00 44.20  ? 307 LEU   A CG     1 
ATOM   6872 C CD1    . LEU   F 1 295 ? 239.967 276.205 227.773 1.00 44.90  ? 307 LEU   A CD1    1 
ATOM   6873 C CD2    . LEU   F 1 295 ? 241.818 277.269 229.057 1.00 51.83  ? 307 LEU   A CD2    1 
ATOM   6874 N N      . GLN   F 1 296 ? 238.498 281.088 230.360 1.00 52.09  ? 308 GLN   A N      1 
ATOM   6875 C CA     . GLN   F 1 296 ? 238.089 282.440 229.997 1.00 54.14  ? 308 GLN   A CA     1 
ATOM   6876 C C      . GLN   F 1 296 ? 239.070 283.477 230.525 1.00 54.56  ? 308 GLN   A C      1 
ATOM   6877 O O      . GLN   F 1 296 ? 239.394 284.447 229.831 1.00 56.79  ? 308 GLN   A O      1 
ATOM   6878 C CB     . GLN   F 1 296 ? 236.681 282.718 230.519 1.00 48.47  ? 308 GLN   A CB     1 
ATOM   6879 C CG     . GLN   F 1 296 ? 235.857 283.612 229.618 1.00 46.79  ? 308 GLN   A CG     1 
ATOM   6880 C CD     . GLN   F 1 296 ? 235.062 282.827 228.602 1.00 45.53  ? 308 GLN   A CD     1 
ATOM   6881 O OE1    . GLN   F 1 296 ? 234.853 281.627 228.757 1.00 45.34  ? 308 GLN   A OE1    1 
ATOM   6882 N NE2    . GLN   F 1 296 ? 234.612 283.502 227.554 1.00 51.46  ? 308 GLN   A NE2    1 
ATOM   6883 N N      . ASN   F 1 297 ? 239.559 283.287 231.747 1.00 56.03  ? 309 ASN   A N      1 
ATOM   6884 C CA     . ASN   F 1 297 ? 240.448 284.239 232.394 1.00 55.94  ? 309 ASN   A CA     1 
ATOM   6885 C C      . ASN   F 1 297 ? 241.920 283.915 232.180 1.00 56.80  ? 309 ASN   A C      1 
ATOM   6886 O O      . ASN   F 1 297 ? 242.781 284.595 232.746 1.00 67.40  ? 309 ASN   A O      1 
ATOM   6887 C CB     . ASN   F 1 297 ? 240.147 284.303 233.892 1.00 53.96  ? 309 ASN   A CB     1 
ATOM   6888 C CG     . ASN   F 1 297 ? 238.709 284.667 234.180 1.00 60.62  ? 309 ASN   A CG     1 
ATOM   6889 O OD1    . ASN   F 1 297 ? 237.909 284.849 233.265 1.00 66.22  ? 309 ASN   A OD1    1 
ATOM   6890 N ND2    . ASN   F 1 297 ? 238.371 284.773 235.458 1.00 61.46  ? 309 ASN   A ND2    1 
ATOM   6891 N N      . SER   F 1 298 ? 242.231 282.901 231.381 1.00 52.98  ? 310 SER   A N      1 
ATOM   6892 C CA     . SER   F 1 298 ? 243.598 282.435 231.205 1.00 51.89  ? 310 SER   A CA     1 
ATOM   6893 C C      . SER   F 1 298 ? 244.123 282.855 229.842 1.00 49.15  ? 310 SER   A C      1 
ATOM   6894 O O      . SER   F 1 298 ? 243.420 282.746 228.833 1.00 55.00  ? 310 SER   A O      1 
ATOM   6895 C CB     . SER   F 1 298 ? 243.684 280.915 231.347 1.00 52.35  ? 310 SER   A CB     1 
ATOM   6896 O OG     . SER   F 1 298 ? 243.363 280.276 230.125 1.00 55.92  ? 310 SER   A OG     1 
ATOM   6897 N N      . GLN   F 1 299 ? 245.362 283.332 229.819 1.00 45.64  ? 311 GLN   A N      1 
ATOM   6898 C CA     . GLN   F 1 299 ? 246.023 283.763 228.597 1.00 48.28  ? 311 GLN   A CA     1 
ATOM   6899 C C      . GLN   F 1 299 ? 247.238 282.880 228.352 1.00 49.10  ? 311 GLN   A C      1 
ATOM   6900 O O      . GLN   F 1 299 ? 248.090 282.729 229.234 1.00 48.59  ? 311 GLN   A O      1 
ATOM   6901 C CB     . GLN   F 1 299 ? 246.412 285.242 228.690 1.00 51.88  ? 311 GLN   A CB     1 
ATOM   6902 C CG     . GLN   F 1 299 ? 247.868 285.511 228.989 1.00 57.45  ? 311 GLN   A CG     1 
ATOM   6903 C CD     . GLN   F 1 299 ? 248.218 286.976 228.847 1.00 57.40  ? 311 GLN   A CD     1 
ATOM   6904 O OE1    . GLN   F 1 299 ? 248.144 287.539 227.757 1.00 56.07  ? 311 GLN   A OE1    1 
ATOM   6905 N NE2    . GLN   F 1 299 ? 248.604 287.601 229.951 1.00 57.95  ? 311 GLN   A NE2    1 
ATOM   6906 N N      . VAL   F 1 300 ? 247.305 282.285 227.164 1.00 48.76  ? 312 VAL   A N      1 
ATOM   6907 C CA     . VAL   F 1 300 ? 248.356 281.336 226.816 1.00 50.08  ? 312 VAL   A CA     1 
ATOM   6908 C C      . VAL   F 1 300 ? 248.833 281.627 225.400 1.00 49.30  ? 312 VAL   A C      1 
ATOM   6909 O O      . VAL   F 1 300 ? 248.039 281.991 224.527 1.00 51.12  ? 312 VAL   A O      1 
ATOM   6910 C CB     . VAL   F 1 300 ? 247.871 279.877 226.948 1.00 46.97  ? 312 VAL   A CB     1 
ATOM   6911 C CG1    . VAL   F 1 300 ? 246.526 279.704 226.269 1.00 46.19  ? 312 VAL   A CG1    1 
ATOM   6912 C CG2    . VAL   F 1 300 ? 248.893 278.921 226.362 1.00 48.61  ? 312 VAL   A CG2    1 
ATOM   6913 N N      . TYR   F 1 301 ? 250.134 281.473 225.178 1.00 49.64  ? 313 TYR   A N      1 
ATOM   6914 C CA     . TYR   F 1 301 ? 250.763 281.757 223.899 1.00 49.86  ? 313 TYR   A CA     1 
ATOM   6915 C C      . TYR   F 1 301 ? 251.263 280.471 223.255 1.00 50.75  ? 313 TYR   A C      1 
ATOM   6916 O O      . TYR   F 1 301 ? 251.464 279.457 223.927 1.00 52.26  ? 313 TYR   A O      1 
ATOM   6917 C CB     . TYR   F 1 301 ? 251.927 282.735 224.072 1.00 51.93  ? 313 TYR   A CB     1 
ATOM   6918 C CG     . TYR   F 1 301 ? 251.607 283.893 224.981 1.00 52.93  ? 313 TYR   A CG     1 
ATOM   6919 C CD1    . TYR   F 1 301 ? 250.953 285.015 224.499 1.00 53.46  ? 313 TYR   A CD1    1 
ATOM   6920 C CD2    . TYR   F 1 301 ? 251.949 283.862 226.323 1.00 55.11  ? 313 TYR   A CD2    1 
ATOM   6921 C CE1    . TYR   F 1 301 ? 250.654 286.075 225.324 1.00 52.59  ? 313 TYR   A CE1    1 
ATOM   6922 C CE2    . TYR   F 1 301 ? 251.652 284.919 227.157 1.00 55.60  ? 313 TYR   A CE2    1 
ATOM   6923 C CZ     . TYR   F 1 301 ? 251.005 286.022 226.651 1.00 55.63  ? 313 TYR   A CZ     1 
ATOM   6924 O OH     . TYR   F 1 301 ? 250.709 287.079 227.476 1.00 60.63  ? 313 TYR   A OH     1 
ATOM   6925 N N      . SER   F 1 302 ? 251.461 280.524 221.940 1.00 49.32  ? 314 SER   A N      1 
ATOM   6926 C CA     . SER   F 1 302 ? 251.942 279.378 221.185 1.00 48.67  ? 314 SER   A CA     1 
ATOM   6927 C C      . SER   F 1 302 ? 252.887 279.845 220.089 1.00 47.78  ? 314 SER   A C      1 
ATOM   6928 O O      . SER   F 1 302 ? 252.837 280.997 219.652 1.00 46.96  ? 314 SER   A O      1 
ATOM   6929 C CB     . SER   F 1 302 ? 250.787 278.580 220.571 1.00 49.74  ? 314 SER   A CB     1 
ATOM   6930 O OG     . SER   F 1 302 ? 251.241 277.782 219.495 1.00 53.36  ? 314 SER   A OG     1 
ATOM   6931 N N      . LEU   F 1 303 ? 253.758 278.936 219.660 1.00 50.64  ? 315 LEU   A N      1 
ATOM   6932 C CA     . LEU   F 1 303 ? 254.674 279.214 218.565 1.00 49.41  ? 315 LEU   A CA     1 
ATOM   6933 C C      . LEU   F 1 303 ? 253.996 278.897 217.239 1.00 47.84  ? 315 LEU   A C      1 
ATOM   6934 O O      . LEU   F 1 303 ? 253.497 277.786 217.038 1.00 48.41  ? 315 LEU   A O      1 
ATOM   6935 C CB     . LEU   F 1 303 ? 255.954 278.395 218.719 1.00 46.29  ? 315 LEU   A CB     1 
ATOM   6936 C CG     . LEU   F 1 303 ? 256.870 278.809 219.869 1.00 41.96  ? 315 LEU   A CG     1 
ATOM   6937 C CD1    . LEU   F 1 303 ? 258.070 277.889 219.951 1.00 44.57  ? 315 LEU   A CD1    1 
ATOM   6938 C CD2    . LEU   F 1 303 ? 257.304 280.253 219.711 1.00 49.39  ? 315 LEU   A CD2    1 
ATOM   6939 N N      . ILE   F 1 304 ? 253.984 279.869 216.334 1.00 49.09  ? 316 ILE   A N      1 
ATOM   6940 C CA     . ILE   F 1 304 ? 253.270 279.757 215.069 1.00 48.16  ? 316 ILE   A CA     1 
ATOM   6941 C C      . ILE   F 1 304 ? 254.293 279.597 213.954 1.00 53.11  ? 316 ILE   A C      1 
ATOM   6942 O O      . ILE   F 1 304 ? 255.189 280.434 213.796 1.00 51.92  ? 316 ILE   A O      1 
ATOM   6943 C CB     . ILE   F 1 304 ? 252.365 280.971 214.819 1.00 49.60  ? 316 ILE   A CB     1 
ATOM   6944 C CG1    . ILE   F 1 304 ? 251.025 280.786 215.529 1.00 51.41  ? 316 ILE   A CG1    1 
ATOM   6945 C CG2    . ILE   F 1 304 ? 252.147 281.171 213.333 1.00 53.64  ? 316 ILE   A CG2    1 
ATOM   6946 C CD1    . ILE   F 1 304 ? 250.119 279.787 214.854 1.00 50.73  ? 316 ILE   A CD1    1 
ATOM   6947 N N      . ARG   F 1 305 ? 254.162 278.518 213.189 1.00 55.96  ? 317 ARG   A N      1 
ATOM   6948 C CA     . ARG   F 1 305 ? 254.997 278.317 212.021 1.00 53.33  ? 317 ARG   A CA     1 
ATOM   6949 C C      . ARG   F 1 305 ? 254.610 279.314 210.934 1.00 58.76  ? 317 ARG   A C      1 
ATOM   6950 O O      . ARG   F 1 305 ? 253.467 279.770 210.875 1.00 62.10  ? 317 ARG   A O      1 
ATOM   6951 C CB     . ARG   F 1 305 ? 254.851 276.889 211.506 1.00 49.77  ? 317 ARG   A CB     1 
ATOM   6952 C CG     . ARG   F 1 305 ? 254.664 275.868 212.606 1.00 51.66  ? 317 ARG   A CG     1 
ATOM   6953 C CD     . ARG   F 1 305 ? 255.014 274.472 212.144 1.00 46.76  ? 317 ARG   A CD     1 
ATOM   6954 N NE     . ARG   F 1 305 ? 254.177 273.477 212.802 1.00 48.39  ? 317 ARG   A NE     1 
ATOM   6955 C CZ     . ARG   F 1 305 ? 254.642 272.408 213.432 1.00 50.92  ? 317 ARG   A CZ     1 
ATOM   6956 N NH1    . ARG   F 1 305 ? 255.938 272.153 213.497 1.00 55.82  ? 317 ARG   A NH1    1 
ATOM   6957 N NH2    . ARG   F 1 305 ? 253.785 271.572 214.010 1.00 54.10  ? 317 ARG   A NH2    1 
ATOM   6958 N N      . PRO   F 1 306 ? 255.549 279.674 210.064 1.00 59.23  ? 318 PRO   A N      1 
ATOM   6959 C CA     . PRO   F 1 306 ? 255.235 280.654 209.020 1.00 54.61  ? 318 PRO   A CA     1 
ATOM   6960 C C      . PRO   F 1 306 ? 254.122 280.149 208.115 1.00 58.09  ? 318 PRO   A C      1 
ATOM   6961 O O      . PRO   F 1 306 ? 254.038 278.960 207.803 1.00 61.13  ? 318 PRO   A O      1 
ATOM   6962 C CB     . PRO   F 1 306 ? 256.559 280.805 208.266 1.00 54.79  ? 318 PRO   A CB     1 
ATOM   6963 C CG     . PRO   F 1 306 ? 257.283 279.531 208.516 1.00 60.85  ? 318 PRO   A CG     1 
ATOM   6964 C CD     . PRO   F 1 306 ? 256.888 279.086 209.893 1.00 60.68  ? 318 PRO   A CD     1 
ATOM   6965 N N      . ASN   F 1 307 ? 253.259 281.073 207.695 1.00 54.48  ? 319 ASN   A N      1 
ATOM   6966 C CA     . ASN   F 1 307 ? 252.120 280.758 206.837 1.00 55.58  ? 319 ASN   A CA     1 
ATOM   6967 C C      . ASN   F 1 307 ? 251.165 279.791 207.543 1.00 53.15  ? 319 ASN   A C      1 
ATOM   6968 O O      . ASN   F 1 307 ? 250.843 278.706 207.057 1.00 54.41  ? 319 ASN   A O      1 
ATOM   6969 C CB     . ASN   F 1 307 ? 252.598 280.183 205.499 1.00 58.35  ? 319 ASN   A CB     1 
ATOM   6970 C CG     . ASN   F 1 307 ? 252.847 281.255 204.464 1.00 67.73  ? 319 ASN   A CG     1 
ATOM   6971 O OD1    . ASN   F 1 307 ? 252.148 282.265 204.421 1.00 73.70  ? 319 ASN   A OD1    1 
ATOM   6972 N ND2    . ASN   F 1 307 ? 253.854 281.044 203.625 1.00 72.15  ? 319 ASN   A ND2    1 
ATOM   6973 N N      . GLU   F 1 308 ? 250.722 280.226 208.719 1.00 53.14  ? 320 GLU   A N      1 
ATOM   6974 C CA     . GLU   F 1 308 ? 249.812 279.443 209.540 1.00 49.93  ? 320 GLU   A CA     1 
ATOM   6975 C C      . GLU   F 1 308 ? 248.844 280.391 210.229 1.00 51.79  ? 320 GLU   A C      1 
ATOM   6976 O O      . GLU   F 1 308 ? 249.250 281.432 210.749 1.00 56.96  ? 320 GLU   A O      1 
ATOM   6977 C CB     . GLU   F 1 308 ? 250.571 278.610 210.579 1.00 49.89  ? 320 GLU   A CB     1 
ATOM   6978 C CG     . GLU   F 1 308 ? 250.832 277.180 210.155 1.00 48.73  ? 320 GLU   A CG     1 
ATOM   6979 C CD     . GLU   F 1 308 ? 251.006 276.252 211.336 1.00 54.31  ? 320 GLU   A CD     1 
ATOM   6980 O OE1    . GLU   F 1 308 ? 251.080 276.750 212.477 1.00 54.62  ? 320 GLU   A OE1    1 
ATOM   6981 O OE2    . GLU   F 1 308 ? 251.065 275.025 211.123 1.00 55.93  ? 320 GLU   A OE2    1 
ATOM   6982 N N      . ASN   F 1 309 ? 247.568 280.021 210.235 1.00 47.44  ? 321 ASN   A N      1 
ATOM   6983 C CA     . ASN   F 1 309 ? 246.533 280.872 210.803 1.00 49.33  ? 321 ASN   A CA     1 
ATOM   6984 C C      . ASN   F 1 309 ? 246.481 280.685 212.312 1.00 53.49  ? 321 ASN   A C      1 
ATOM   6985 O O      . ASN   F 1 309 ? 246.238 279.563 212.776 1.00 57.76  ? 321 ASN   A O      1 
ATOM   6986 C CB     . ASN   F 1 309 ? 245.181 280.549 210.192 1.00 49.25  ? 321 ASN   A CB     1 
ATOM   6987 C CG     . ASN   F 1 309 ? 244.201 281.694 210.309 1.00 53.30  ? 321 ASN   A CG     1 
ATOM   6988 O OD1    . ASN   F 1 309 ? 244.499 282.721 210.915 1.00 57.65  ? 321 ASN   A OD1    1 
ATOM   6989 N ND2    . ASN   F 1 309 ? 243.021 281.523 209.729 1.00 51.86  ? 321 ASN   A ND2    1 
ATOM   6990 N N      . PRO   F 1 310 ? 246.701 281.732 213.109 1.00 51.96  ? 322 PRO   A N      1 
ATOM   6991 C CA     . PRO   F 1 310 ? 246.598 281.567 214.567 1.00 51.94  ? 322 PRO   A CA     1 
ATOM   6992 C C      . PRO   F 1 310 ? 245.223 281.118 215.023 1.00 51.43  ? 322 PRO   A C      1 
ATOM   6993 O O      . PRO   F 1 310 ? 245.119 280.382 216.011 1.00 53.15  ? 322 PRO   A O      1 
ATOM   6994 C CB     . PRO   F 1 310 ? 246.948 282.963 215.103 1.00 47.41  ? 322 PRO   A CB     1 
ATOM   6995 C CG     . PRO   F 1 310 ? 246.706 283.889 213.964 1.00 50.32  ? 322 PRO   A CG     1 
ATOM   6996 C CD     . PRO   F 1 310 ? 247.035 283.114 212.728 1.00 51.36  ? 322 PRO   A CD     1 
ATOM   6997 N N      . ALA   F 1 311 ? 244.160 281.539 214.334 1.00 49.88  ? 323 ALA   A N      1 
ATOM   6998 C CA     . ALA   F 1 311 ? 242.816 281.138 214.735 1.00 49.87  ? 323 ALA   A CA     1 
ATOM   6999 C C      . ALA   F 1 311 ? 242.631 279.631 214.624 1.00 48.77  ? 323 ALA   A C      1 
ATOM   7000 O O      . ALA   F 1 311 ? 242.002 279.009 215.487 1.00 50.55  ? 323 ALA   A O      1 
ATOM   7001 C CB     . ALA   F 1 311 ? 241.775 281.871 213.891 1.00 46.71  ? 323 ALA   A CB     1 
ATOM   7002 N N      . HIS   F 1 312 ? 243.159 279.026 213.559 1.00 50.64  ? 324 HIS   A N      1 
ATOM   7003 C CA     . HIS   F 1 312 ? 243.025 277.583 213.396 1.00 51.67  ? 324 HIS   A CA     1 
ATOM   7004 C C      . HIS   F 1 312 ? 243.802 276.831 214.469 1.00 51.55  ? 324 HIS   A C      1 
ATOM   7005 O O      . HIS   F 1 312 ? 243.321 275.822 214.998 1.00 52.43  ? 324 HIS   A O      1 
ATOM   7006 C CB     . HIS   F 1 312 ? 243.482 277.171 211.999 1.00 48.49  ? 324 HIS   A CB     1 
ATOM   7007 C CG     . HIS   F 1 312 ? 242.587 277.664 210.907 1.00 48.10  ? 324 HIS   A CG     1 
ATOM   7008 N ND1    . HIS   F 1 312 ? 243.039 277.926 209.633 1.00 52.17  ? 324 HIS   A ND1    1 
ATOM   7009 C CD2    . HIS   F 1 312 ? 241.265 277.956 210.904 1.00 48.37  ? 324 HIS   A CD2    1 
ATOM   7010 C CE1    . HIS   F 1 312 ? 242.033 278.351 208.889 1.00 49.17  ? 324 HIS   A CE1    1 
ATOM   7011 N NE2    . HIS   F 1 312 ? 240.946 278.378 209.637 1.00 46.71  ? 324 HIS   A NE2    1 
ATOM   7012 N N      . LYS   F 1 313 ? 245.005 277.299 214.803 1.00 48.31  ? 325 LYS   A N      1 
ATOM   7013 C CA     . LYS   F 1 313 ? 245.751 276.675 215.890 1.00 48.84  ? 325 LYS   A CA     1 
ATOM   7014 C C      . LYS   F 1 313 ? 245.036 276.862 217.223 1.00 48.11  ? 325 LYS   A C      1 
ATOM   7015 O O      . LYS   F 1 313 ? 245.004 275.945 218.050 1.00 46.14  ? 325 LYS   A O      1 
ATOM   7016 C CB     . LYS   F 1 313 ? 247.170 277.235 215.952 1.00 47.31  ? 325 LYS   A CB     1 
ATOM   7017 C CG     . LYS   F 1 313 ? 248.105 276.432 216.840 1.00 47.54  ? 325 LYS   A CG     1 
ATOM   7018 C CD     . LYS   F 1 313 ? 249.535 276.927 216.736 1.00 47.53  ? 325 LYS   A CD     1 
ATOM   7019 C CE     . LYS   F 1 313 ? 250.280 276.229 215.614 1.00 45.96  ? 325 LYS   A CE     1 
ATOM   7020 N NZ     . LYS   F 1 313 ? 250.057 274.762 215.640 1.00 49.34  ? 325 LYS   A NZ     1 
ATOM   7021 N N      . SER   F 1 314 ? 244.456 278.041 217.452 1.00 48.93  ? 326 SER   A N      1 
ATOM   7022 C CA     . SER   F 1 314 ? 243.701 278.258 218.681 1.00 48.09  ? 326 SER   A CA     1 
ATOM   7023 C C      . SER   F 1 314 ? 242.479 277.350 218.739 1.00 48.80  ? 326 SER   A C      1 
ATOM   7024 O O      . SER   F 1 314 ? 242.118 276.849 219.809 1.00 53.17  ? 326 SER   A O      1 
ATOM   7025 C CB     . SER   F 1 314 ? 243.293 279.726 218.799 1.00 45.81  ? 326 SER   A CB     1 
ATOM   7026 O OG     . SER   F 1 314 ? 242.479 280.118 217.710 1.00 55.85  ? 326 SER   A OG     1 
ATOM   7027 N N      . GLN   F 1 315 ? 241.825 277.132 217.597 1.00 46.97  ? 327 GLN   A N      1 
ATOM   7028 C CA     . GLN   F 1 315 ? 240.695 276.211 217.565 1.00 47.13  ? 327 GLN   A CA     1 
ATOM   7029 C C      . GLN   F 1 315 ? 241.139 274.787 217.866 1.00 47.85  ? 327 GLN   A C      1 
ATOM   7030 O O      . GLN   F 1 315 ? 240.429 274.036 218.545 1.00 51.02  ? 327 GLN   A O      1 
ATOM   7031 C CB     . GLN   F 1 315 ? 239.999 276.281 216.207 1.00 46.89  ? 327 GLN   A CB     1 
ATOM   7032 C CG     . GLN   F 1 315 ? 239.000 275.168 215.971 1.00 44.35  ? 327 GLN   A CG     1 
ATOM   7033 C CD     . GLN   F 1 315 ? 238.874 274.809 214.510 1.00 46.50  ? 327 GLN   A CD     1 
ATOM   7034 O OE1    . GLN   F 1 315 ? 238.745 275.683 213.655 1.00 50.45  ? 327 GLN   A OE1    1 
ATOM   7035 N NE2    . GLN   F 1 315 ? 238.905 273.517 214.213 1.00 44.11  ? 327 GLN   A NE2    1 
ATOM   7036 N N      . LEU   F 1 316 ? 242.309 274.394 217.361 1.00 46.71  ? 328 LEU   A N      1 
ATOM   7037 C CA     . LEU   F 1 316 ? 242.822 273.059 217.641 1.00 44.15  ? 328 LEU   A CA     1 
ATOM   7038 C C      . LEU   F 1 316 ? 243.058 272.863 219.133 1.00 44.76  ? 328 LEU   A C      1 
ATOM   7039 O O      . LEU   F 1 316 ? 242.724 271.811 219.689 1.00 46.27  ? 328 LEU   A O      1 
ATOM   7040 C CB     . LEU   F 1 316 ? 244.108 272.822 216.853 1.00 43.59  ? 328 LEU   A CB     1 
ATOM   7041 C CG     . LEU   F 1 316 ? 244.736 271.434 216.951 1.00 44.84  ? 328 LEU   A CG     1 
ATOM   7042 C CD1    . LEU   F 1 316 ? 244.072 270.488 215.970 1.00 44.12  ? 328 LEU   A CD1    1 
ATOM   7043 C CD2    . LEU   F 1 316 ? 246.226 271.515 216.690 1.00 47.96  ? 328 LEU   A CD2    1 
ATOM   7044 N N      . VAL   F 1 317 ? 243.634 273.865 219.798 1.00 45.40  ? 329 VAL   A N      1 
ATOM   7045 C CA     . VAL   F 1 317 ? 243.872 273.762 221.233 1.00 45.83  ? 329 VAL   A CA     1 
ATOM   7046 C C      . VAL   F 1 317 ? 242.554 273.784 221.997 1.00 47.86  ? 329 VAL   A C      1 
ATOM   7047 O O      . VAL   F 1 317 ? 242.390 273.080 223.000 1.00 51.42  ? 329 VAL   A O      1 
ATOM   7048 C CB     . VAL   F 1 317 ? 244.820 274.880 221.699 1.00 47.00  ? 329 VAL   A CB     1 
ATOM   7049 C CG1    . VAL   F 1 317 ? 244.942 274.876 223.211 1.00 47.04  ? 329 VAL   A CG1    1 
ATOM   7050 C CG2    . VAL   F 1 317 ? 246.182 274.718 221.054 1.00 48.61  ? 329 VAL   A CG2    1 
ATOM   7051 N N      . TRP   F 1 318 ? 241.594 274.590 221.539 1.00 44.87  ? 330 TRP   A N      1 
ATOM   7052 C CA     . TRP   F 1 318 ? 240.299 274.647 222.208 1.00 45.38  ? 330 TRP   A CA     1 
ATOM   7053 C C      . TRP   F 1 318 ? 239.594 273.297 222.148 1.00 47.42  ? 330 TRP   A C      1 
ATOM   7054 O O      . TRP   F 1 318 ? 239.000 272.848 223.134 1.00 48.36  ? 330 TRP   A O      1 
ATOM   7055 C CB     . TRP   F 1 318 ? 239.427 275.736 221.581 1.00 42.59  ? 330 TRP   A CB     1 
ATOM   7056 C CG     . TRP   F 1 318 ? 238.103 275.899 222.257 1.00 42.35  ? 330 TRP   A CG     1 
ATOM   7057 C CD1    . TRP   F 1 318 ? 237.819 276.715 223.311 1.00 45.88  ? 330 TRP   A CD1    1 
ATOM   7058 C CD2    . TRP   F 1 318 ? 236.888 275.209 221.946 1.00 42.41  ? 330 TRP   A CD2    1 
ATOM   7059 N NE1    . TRP   F 1 318 ? 236.499 276.588 223.667 1.00 43.46  ? 330 TRP   A NE1    1 
ATOM   7060 C CE2    . TRP   F 1 318 ? 235.906 275.668 222.845 1.00 43.06  ? 330 TRP   A CE2    1 
ATOM   7061 C CE3    . TRP   F 1 318 ? 236.533 274.252 220.992 1.00 42.11  ? 330 TRP   A CE3    1 
ATOM   7062 C CZ2    . TRP   F 1 318 ? 234.596 275.202 222.817 1.00 45.88  ? 330 TRP   A CZ2    1 
ATOM   7063 C CZ3    . TRP   F 1 318 ? 235.234 273.791 220.967 1.00 42.34  ? 330 TRP   A CZ3    1 
ATOM   7064 C CH2    . TRP   F 1 318 ? 234.280 274.267 221.873 1.00 46.83  ? 330 TRP   A CH2    1 
ATOM   7065 N N      . MET   F 1 319 ? 239.642 272.638 220.989 1.00 46.83  ? 331 MET   A N      1 
ATOM   7066 C CA     . MET   F 1 319 ? 239.002 271.333 220.858 1.00 44.86  ? 331 MET   A CA     1 
ATOM   7067 C C      . MET   F 1 319 ? 239.702 270.285 221.712 1.00 48.96  ? 331 MET   A C      1 
ATOM   7068 O O      . MET   F 1 319 ? 239.046 269.462 222.362 1.00 53.31  ? 331 MET   A O      1 
ATOM   7069 C CB     . MET   F 1 319 ? 238.977 270.902 219.394 1.00 44.17  ? 331 MET   A CB     1 
ATOM   7070 C CG     . MET   F 1 319 ? 238.037 271.714 218.527 1.00 46.91  ? 331 MET   A CG     1 
ATOM   7071 S SD     . MET   F 1 319 ? 237.985 271.091 216.841 1.00 54.15  ? 331 MET   A SD     1 
ATOM   7072 C CE     . MET   F 1 319 ? 239.090 269.693 216.982 1.00 52.57  ? 331 MET   A CE     1 
ATOM   7073 N N      . ALA   F 1 320 ? 241.036 270.294 221.720 1.00 47.51  ? 332 ALA   A N      1 
ATOM   7074 C CA     . ALA   F 1 320 ? 241.771 269.337 222.538 1.00 44.32  ? 332 ALA   A CA     1 
ATOM   7075 C C      . ALA   F 1 320 ? 241.507 269.564 224.021 1.00 45.68  ? 332 ALA   A C      1 
ATOM   7076 O O      . ALA   F 1 320 ? 241.450 268.607 224.801 1.00 48.48  ? 332 ALA   A O      1 
ATOM   7077 C CB     . ALA   F 1 320 ? 243.265 269.428 222.237 1.00 44.01  ? 332 ALA   A CB     1 
ATOM   7078 N N      . CYS   F 1 321 ? 241.346 270.824 224.428 1.00 46.81  ? 333 CYS   A N      1 
ATOM   7079 C CA     . CYS   F 1 321 ? 241.095 271.116 225.835 1.00 47.64  ? 333 CYS   A CA     1 
ATOM   7080 C C      . CYS   F 1 321 ? 239.800 270.472 226.309 1.00 48.34  ? 333 CYS   A C      1 
ATOM   7081 O O      . CYS   F 1 321 ? 239.742 269.912 227.409 1.00 50.88  ? 333 CYS   A O      1 
ATOM   7082 C CB     . CYS   F 1 321 ? 241.053 272.627 226.058 1.00 46.18  ? 333 CYS   A CB     1 
ATOM   7083 S SG     . CYS   F 1 321 ? 242.671 273.416 226.155 1.00 66.56  ? 333 CYS   A SG     1 
ATOM   7084 N N      . HIS   F 1 322 ? 238.753 270.539 225.493 1.00 48.18  ? 334 HIS   A N      1 
ATOM   7085 C CA     . HIS   F 1 322 ? 237.441 270.024 225.855 1.00 46.38  ? 334 HIS   A CA     1 
ATOM   7086 C C      . HIS   F 1 322 ? 237.141 268.678 225.209 1.00 47.06  ? 334 HIS   A C      1 
ATOM   7087 O O      . HIS   F 1 322 ? 236.016 268.184 225.325 1.00 51.79  ? 334 HIS   A O      1 
ATOM   7088 C CB     . HIS   F 1 322 ? 236.367 271.046 225.483 1.00 46.70  ? 334 HIS   A CB     1 
ATOM   7089 C CG     . HIS   F 1 322 ? 236.477 272.332 226.239 1.00 47.25  ? 334 HIS   A CG     1 
ATOM   7090 N ND1    . HIS   F 1 322 ? 236.947 273.494 225.666 1.00 45.83  ? 334 HIS   A ND1    1 
ATOM   7091 C CD2    . HIS   F 1 322 ? 236.189 272.638 227.526 1.00 49.09  ? 334 HIS   A CD2    1 
ATOM   7092 C CE1    . HIS   F 1 322 ? 236.939 274.461 226.565 1.00 45.73  ? 334 HIS   A CE1    1 
ATOM   7093 N NE2    . HIS   F 1 322 ? 236.483 273.968 227.702 1.00 48.43  ? 334 HIS   A NE2    1 
ATOM   7094 N N      . SER   F 1 323 ? 238.122 268.070 224.545 1.00 49.41  ? 335 SER   A N      1 
ATOM   7095 C CA     . SER   F 1 323 ? 237.957 266.753 223.931 1.00 49.12  ? 335 SER   A CA     1 
ATOM   7096 C C      . SER   F 1 323 ? 236.790 266.738 222.948 1.00 50.50  ? 335 SER   A C      1 
ATOM   7097 O O      . SER   F 1 323 ? 235.997 265.797 222.912 1.00 53.02  ? 335 SER   A O      1 
ATOM   7098 C CB     . SER   F 1 323 ? 237.782 265.670 224.996 1.00 46.44  ? 335 SER   A CB     1 
ATOM   7099 O OG     . SER   F 1 323 ? 236.502 265.747 225.592 1.00 51.97  ? 335 SER   A OG     1 
ATOM   7100 N N      . ALA   F 1 324 ? 236.684 267.792 222.139 1.00 48.44  ? 336 ALA   A N      1 
ATOM   7101 C CA     . ALA   F 1 324 ? 235.643 267.901 221.126 1.00 46.92  ? 336 ALA   A CA     1 
ATOM   7102 C C      . ALA   F 1 324 ? 236.149 267.527 219.738 1.00 47.72  ? 336 ALA   A C      1 
ATOM   7103 O O      . ALA   F 1 324 ? 235.628 268.020 218.733 1.00 49.23  ? 336 ALA   A O      1 
ATOM   7104 C CB     . ALA   F 1 324 ? 235.059 269.312 221.114 1.00 44.32  ? 336 ALA   A CB     1 
ATOM   7105 N N      . ALA   F 1 325 ? 237.157 266.657 219.665 1.00 44.23  ? 337 ALA   A N      1 
ATOM   7106 C CA     . ALA   F 1 325 ? 237.715 266.280 218.371 1.00 45.34  ? 337 ALA   A CA     1 
ATOM   7107 C C      . ALA   F 1 325 ? 236.690 265.547 217.515 1.00 50.48  ? 337 ALA   A C      1 
ATOM   7108 O O      . ALA   F 1 325 ? 236.587 265.794 216.309 1.00 56.96  ? 337 ALA   A O      1 
ATOM   7109 C CB     . ALA   F 1 325 ? 238.962 265.421 218.569 1.00 48.13  ? 337 ALA   A CB     1 
ATOM   7110 N N      . PHE   F 1 326 ? 235.922 264.644 218.120 1.00 47.62  ? 338 PHE   A N      1 
ATOM   7111 C CA     . PHE   F 1 326 ? 234.949 263.833 217.402 1.00 44.78  ? 338 PHE   A CA     1 
ATOM   7112 C C      . PHE   F 1 326 ? 233.519 264.323 217.580 1.00 48.75  ? 338 PHE   A C      1 
ATOM   7113 O O      . PHE   F 1 326 ? 232.582 263.626 217.180 1.00 56.20  ? 338 PHE   A O      1 
ATOM   7114 C CB     . PHE   F 1 326 ? 235.054 262.376 217.847 1.00 47.24  ? 338 PHE   A CB     1 
ATOM   7115 C CG     . PHE   F 1 326 ? 236.450 261.838 217.825 1.00 48.22  ? 338 PHE   A CG     1 
ATOM   7116 C CD1    . PHE   F 1 326 ? 237.150 261.743 216.638 1.00 48.85  ? 338 PHE   A CD1    1 
ATOM   7117 C CD2    . PHE   F 1 326 ? 237.065 261.431 218.994 1.00 48.83  ? 338 PHE   A CD2    1 
ATOM   7118 C CE1    . PHE   F 1 326 ? 238.436 261.247 216.615 1.00 48.62  ? 338 PHE   A CE1    1 
ATOM   7119 C CE2    . PHE   F 1 326 ? 238.350 260.936 218.976 1.00 49.83  ? 338 PHE   A CE2    1 
ATOM   7120 C CZ     . PHE   F 1 326 ? 239.036 260.843 217.785 1.00 48.86  ? 338 PHE   A CZ     1 
ATOM   7121 N N      . GLU   F 1 327 ? 233.329 265.499 218.165 1.00 48.59  ? 339 GLU   A N      1 
ATOM   7122 C CA     . GLU   F 1 327 ? 231.994 266.016 218.401 1.00 47.27  ? 339 GLU   A CA     1 
ATOM   7123 C C      . GLU   F 1 327 ? 231.454 266.699 217.146 1.00 48.70  ? 339 GLU   A C      1 
ATOM   7124 O O      . GLU   F 1 327 ? 232.196 267.041 216.221 1.00 48.42  ? 339 GLU   A O      1 
ATOM   7125 C CB     . GLU   F 1 327 ? 232.005 266.982 219.588 1.00 46.47  ? 339 GLU   A CB     1 
ATOM   7126 C CG     . GLU   F 1 327 ? 230.745 267.804 219.757 1.00 48.35  ? 339 GLU   A CG     1 
ATOM   7127 C CD     . GLU   F 1 327 ? 229.703 267.092 220.588 1.00 54.66  ? 339 GLU   A CD     1 
ATOM   7128 O OE1    . GLU   F 1 327 ? 229.788 265.855 220.715 1.00 63.78  ? 339 GLU   A OE1    1 
ATOM   7129 O OE2    . GLU   F 1 327 ? 228.795 267.768 221.111 1.00 55.09  ? 339 GLU   A OE2    1 
ATOM   7130 N N      . ASP   F 1 328 ? 230.136 266.872 217.114 1.00 50.26  ? 340 ASP   A N      1 
ATOM   7131 C CA     . ASP   F 1 328 ? 229.496 267.554 216.000 1.00 47.73  ? 340 ASP   A CA     1 
ATOM   7132 C C      . ASP   F 1 328 ? 230.033 268.974 215.866 1.00 49.02  ? 340 ASP   A C      1 
ATOM   7133 O O      . ASP   F 1 328 ? 230.129 269.716 216.847 1.00 48.65  ? 340 ASP   A O      1 
ATOM   7134 C CB     . ASP   F 1 328 ? 227.981 267.576 216.206 1.00 49.00  ? 340 ASP   A CB     1 
ATOM   7135 C CG     . ASP   F 1 328 ? 227.231 268.025 214.976 1.00 55.62  ? 340 ASP   A CG     1 
ATOM   7136 O OD1    . ASP   F 1 328 ? 227.882 268.490 214.020 1.00 60.36  ? 340 ASP   A OD1    1 
ATOM   7137 O OD2    . ASP   F 1 328 ? 225.989 267.910 214.963 1.00 56.07  ? 340 ASP   A OD2    1 
ATOM   7138 N N      . LEU   F 1 329 ? 230.383 269.351 214.636 1.00 51.37  ? 341 LEU   A N      1 
ATOM   7139 C CA     . LEU   F 1 329 ? 230.932 270.683 214.406 1.00 49.19  ? 341 LEU   A CA     1 
ATOM   7140 C C      . LEU   F 1 329 ? 229.907 271.769 214.701 1.00 46.55  ? 341 LEU   A C      1 
ATOM   7141 O O      . LEU   F 1 329 ? 230.276 272.868 215.128 1.00 47.67  ? 341 LEU   A O      1 
ATOM   7142 C CB     . LEU   F 1 329 ? 231.434 270.802 212.967 1.00 51.81  ? 341 LEU   A CB     1 
ATOM   7143 C CG     . LEU   F 1 329 ? 232.903 270.465 212.703 1.00 47.47  ? 341 LEU   A CG     1 
ATOM   7144 C CD1    . LEU   F 1 329 ? 233.803 271.570 213.219 1.00 54.17  ? 341 LEU   A CD1    1 
ATOM   7145 C CD2    . LEU   F 1 329 ? 233.274 269.137 213.333 1.00 47.58  ? 341 LEU   A CD2    1 
ATOM   7146 N N      . ARG   F 1 330 ? 228.624 271.484 214.477 1.00 45.50  ? 342 ARG   A N      1 
ATOM   7147 C CA     . ARG   F 1 330 ? 227.586 272.474 214.740 1.00 46.35  ? 342 ARG   A CA     1 
ATOM   7148 C C      . ARG   F 1 330 ? 227.482 272.783 216.228 1.00 49.00  ? 342 ARG   A C      1 
ATOM   7149 O O      . ARG   F 1 330 ? 227.370 273.948 216.625 1.00 50.64  ? 342 ARG   A O      1 
ATOM   7150 C CB     . ARG   F 1 330 ? 226.248 271.978 214.193 1.00 45.40  ? 342 ARG   A CB     1 
ATOM   7151 C CG     . ARG   F 1 330 ? 226.355 271.355 212.816 1.00 48.01  ? 342 ARG   A CG     1 
ATOM   7152 C CD     . ARG   F 1 330 ? 225.017 270.844 212.322 1.00 49.26  ? 342 ARG   A CD     1 
ATOM   7153 N NE     . ARG   F 1 330 ? 224.852 269.420 212.584 1.00 47.73  ? 342 ARG   A NE     1 
ATOM   7154 C CZ     . ARG   F 1 330 ? 223.725 268.862 213.000 1.00 48.28  ? 342 ARG   A CZ     1 
ATOM   7155 N NH1    . ARG   F 1 330 ? 222.630 269.576 213.193 1.00 51.70  ? 342 ARG   A NH1    1 
ATOM   7156 N NH2    . ARG   F 1 330 ? 223.695 267.553 213.227 1.00 49.25  ? 342 ARG   A NH2    1 
ATOM   7157 N N      . VAL   F 1 331 ? 227.513 271.749 217.069 1.00 49.95  ? 343 VAL   A N      1 
ATOM   7158 C CA     . VAL   F 1 331 ? 227.449 271.970 218.510 1.00 47.78  ? 343 VAL   A CA     1 
ATOM   7159 C C      . VAL   F 1 331 ? 228.740 272.601 219.013 1.00 47.34  ? 343 VAL   A C      1 
ATOM   7160 O O      . VAL   F 1 331 ? 228.720 273.475 219.887 1.00 48.03  ? 343 VAL   A O      1 
ATOM   7161 C CB     . VAL   F 1 331 ? 227.133 270.653 219.242 1.00 44.73  ? 343 VAL   A CB     1 
ATOM   7162 C CG1    . VAL   F 1 331 ? 228.130 269.583 218.858 1.00 49.14  ? 343 VAL   A CG1    1 
ATOM   7163 C CG2    . VAL   F 1 331 ? 227.134 270.872 220.742 1.00 46.23  ? 343 VAL   A CG2    1 
ATOM   7164 N N      . SER   F 1 332 ? 229.884 272.168 218.478 1.00 47.56  ? 344 SER   A N      1 
ATOM   7165 C CA     . SER   F 1 332 ? 231.150 272.794 218.843 1.00 45.33  ? 344 SER   A CA     1 
ATOM   7166 C C      . SER   F 1 332 ? 231.192 274.251 218.400 1.00 45.87  ? 344 SER   A C      1 
ATOM   7167 O O      . SER   F 1 332 ? 231.659 275.120 219.143 1.00 47.38  ? 344 SER   A O      1 
ATOM   7168 C CB     . SER   F 1 332 ? 232.316 272.014 218.236 1.00 44.74  ? 344 SER   A CB     1 
ATOM   7169 O OG     . SER   F 1 332 ? 232.491 270.770 218.887 1.00 46.11  ? 344 SER   A OG     1 
ATOM   7170 N N      . SER   F 1 333 ? 230.717 274.536 217.186 1.00 47.19  ? 345 SER   A N      1 
ATOM   7171 C CA     . SER   F 1 333 ? 230.677 275.915 216.714 1.00 48.21  ? 345 SER   A CA     1 
ATOM   7172 C C      . SER   F 1 333 ? 229.735 276.759 217.560 1.00 47.44  ? 345 SER   A C      1 
ATOM   7173 O O      . SER   F 1 333 ? 230.036 277.916 217.874 1.00 49.38  ? 345 SER   A O      1 
ATOM   7174 C CB     . SER   F 1 333 ? 230.257 275.956 215.246 1.00 46.41  ? 345 SER   A CB     1 
ATOM   7175 O OG     . SER   F 1 333 ? 231.189 275.270 214.432 1.00 50.60  ? 345 SER   A OG     1 
ATOM   7176 N N      . PHE   F 1 334 ? 228.586 276.197 217.934 1.00 45.56  ? 346 PHE   A N      1 
ATOM   7177 C CA     . PHE   F 1 334 ? 227.613 276.948 218.717 1.00 47.30  ? 346 PHE   A CA     1 
ATOM   7178 C C      . PHE   F 1 334 ? 228.175 277.308 220.087 1.00 47.09  ? 346 PHE   A C      1 
ATOM   7179 O O      . PHE   F 1 334 ? 227.963 278.421 220.581 1.00 47.54  ? 346 PHE   A O      1 
ATOM   7180 C CB     . PHE   F 1 334 ? 226.325 276.134 218.843 1.00 48.85  ? 346 PHE   A CB     1 
ATOM   7181 C CG     . PHE   F 1 334 ? 225.300 276.745 219.747 1.00 48.97  ? 346 PHE   A CG     1 
ATOM   7182 C CD1    . PHE   F 1 334 ? 224.640 277.903 219.379 1.00 45.90  ? 346 PHE   A CD1    1 
ATOM   7183 C CD2    . PHE   F 1 334 ? 224.975 276.151 220.951 1.00 53.17  ? 346 PHE   A CD2    1 
ATOM   7184 C CE1    . PHE   F 1 334 ? 223.690 278.463 220.202 1.00 48.39  ? 346 PHE   A CE1    1 
ATOM   7185 C CE2    . PHE   F 1 334 ? 224.024 276.709 221.777 1.00 54.09  ? 346 PHE   A CE2    1 
ATOM   7186 C CZ     . PHE   F 1 334 ? 223.382 277.867 221.401 1.00 52.20  ? 346 PHE   A CZ     1 
ATOM   7187 N N      . ILE   F 1 335 ? 228.901 276.380 220.712 1.00 47.53  ? 347 ILE   A N      1 
ATOM   7188 C CA     . ILE   F 1 335 ? 229.458 276.631 222.037 1.00 49.02  ? 347 ILE   A CA     1 
ATOM   7189 C C      . ILE   F 1 335 ? 230.579 277.660 221.966 1.00 46.24  ? 347 ILE   A C      1 
ATOM   7190 O O      . ILE   F 1 335 ? 230.657 278.574 222.796 1.00 47.99  ? 347 ILE   A O      1 
ATOM   7191 C CB     . ILE   F 1 335 ? 229.942 275.312 222.665 1.00 45.91  ? 347 ILE   A CB     1 
ATOM   7192 C CG1    . ILE   F 1 335 ? 228.760 274.378 222.919 1.00 47.56  ? 347 ILE   A CG1    1 
ATOM   7193 C CG2    . ILE   F 1 335 ? 230.697 275.581 223.952 1.00 46.81  ? 347 ILE   A CG2    1 
ATOM   7194 C CD1    . ILE   F 1 335 ? 229.160 273.004 223.381 1.00 50.17  ? 347 ILE   A CD1    1 
ATOM   7195 N N      . ARG   F 1 336 ? 231.469 277.527 220.983 1.00 44.53  ? 348 ARG   A N      1 
ATOM   7196 C CA     . ARG   F 1 336 ? 232.615 278.426 220.898 1.00 45.98  ? 348 ARG   A CA     1 
ATOM   7197 C C      . ARG   F 1 336 ? 232.195 279.825 220.463 1.00 48.22  ? 348 ARG   A C      1 
ATOM   7198 O O      . ARG   F 1 336 ? 232.767 280.821 220.920 1.00 46.65  ? 348 ARG   A O      1 
ATOM   7199 C CB     . ARG   F 1 336 ? 233.654 277.849 219.939 1.00 44.77  ? 348 ARG   A CB     1 
ATOM   7200 C CG     . ARG   F 1 336 ? 234.779 278.796 219.587 1.00 46.87  ? 348 ARG   A CG     1 
ATOM   7201 C CD     . ARG   F 1 336 ? 236.110 278.072 219.603 1.00 44.70  ? 348 ARG   A CD     1 
ATOM   7202 N NE     . ARG   F 1 336 ? 237.233 278.988 219.763 1.00 45.07  ? 348 ARG   A NE     1 
ATOM   7203 C CZ     . ARG   F 1 336 ? 238.207 279.132 218.876 1.00 47.53  ? 348 ARG   A CZ     1 
ATOM   7204 N NH1    . ARG   F 1 336 ? 238.223 278.440 217.750 1.00 47.64  ? 348 ARG   A NH1    1 
ATOM   7205 N NH2    . ARG   F 1 336 ? 239.188 279.994 219.125 1.00 51.62  ? 348 ARG   A NH2    1 
ATOM   7206 N N      . GLY   F 1 337 ? 231.201 279.921 219.586 1.00 48.40  ? 349 GLY   A N      1 
ATOM   7207 C CA     . GLY   F 1 337 ? 230.740 281.182 219.057 1.00 45.27  ? 349 GLY   A CA     1 
ATOM   7208 C C      . GLY   F 1 337 ? 231.344 281.555 217.720 1.00 50.20  ? 349 GLY   A C      1 
ATOM   7209 O O      . GLY   F 1 337 ? 230.764 282.374 217.000 1.00 55.35  ? 349 GLY   A O      1 
ATOM   7210 N N      . THR   F 1 338 ? 232.488 280.974 217.373 1.00 50.77  ? 350 THR   A N      1 
ATOM   7211 C CA     . THR   F 1 338 ? 233.103 281.138 216.066 1.00 49.93  ? 350 THR   A CA     1 
ATOM   7212 C C      . THR   F 1 338 ? 233.152 279.780 215.386 1.00 50.87  ? 350 THR   A C      1 
ATOM   7213 O O      . THR   F 1 338 ? 233.388 278.759 216.038 1.00 55.30  ? 350 THR   A O      1 
ATOM   7214 C CB     . THR   F 1 338 ? 234.514 281.728 216.169 1.00 48.32  ? 350 THR   A CB     1 
ATOM   7215 O OG1    . THR   F 1 338 ? 235.459 280.677 216.393 1.00 48.28  ? 350 THR   A OG1    1 
ATOM   7216 C CG2    . THR   F 1 338 ? 234.594 282.724 217.311 1.00 47.45  ? 350 THR   A CG2    1 
ATOM   7217 N N      . LYS   F 1 339 ? 232.924 279.774 214.078 1.00 49.89  ? 351 LYS   A N      1 
ATOM   7218 C CA     . LYS   F 1 339 ? 232.773 278.520 213.357 1.00 51.84  ? 351 LYS   A CA     1 
ATOM   7219 C C      . LYS   F 1 339 ? 234.018 277.654 213.506 1.00 49.07  ? 351 LYS   A C      1 
ATOM   7220 O O      . LYS   F 1 339 ? 235.145 278.130 213.353 1.00 49.63  ? 351 LYS   A O      1 
ATOM   7221 C CB     . LYS   F 1 339 ? 232.490 278.799 211.883 1.00 47.17  ? 351 LYS   A CB     1 
ATOM   7222 C CG     . LYS   F 1 339 ? 233.038 277.755 210.938 1.00 50.82  ? 351 LYS   A CG     1 
ATOM   7223 C CD     . LYS   F 1 339 ? 232.364 277.852 209.586 1.00 57.29  ? 351 LYS   A CD     1 
ATOM   7224 C CE     . LYS   F 1 339 ? 230.854 277.831 209.734 1.00 65.09  ? 351 LYS   A CE     1 
ATOM   7225 N NZ     . LYS   F 1 339 ? 230.408 276.753 210.657 1.00 64.70  ? 351 LYS   A NZ     1 
ATOM   7226 N N      . VAL   F 1 340 ? 233.807 276.379 213.812 1.00 46.38  ? 352 VAL   A N      1 
ATOM   7227 C CA     . VAL   F 1 340 ? 234.889 275.407 213.885 1.00 46.99  ? 352 VAL   A CA     1 
ATOM   7228 C C      . VAL   F 1 340 ? 235.043 274.755 212.519 1.00 47.03  ? 352 VAL   A C      1 
ATOM   7229 O O      . VAL   F 1 340 ? 234.078 274.218 211.963 1.00 46.93  ? 352 VAL   A O      1 
ATOM   7230 C CB     . VAL   F 1 340 ? 234.616 274.356 214.974 1.00 46.61  ? 352 VAL   A CB     1 
ATOM   7231 C CG1    . VAL   F 1 340 ? 235.781 273.391 215.078 1.00 44.41  ? 352 VAL   A CG1    1 
ATOM   7232 C CG2    . VAL   F 1 340 ? 234.366 275.032 216.307 1.00 48.89  ? 352 VAL   A CG2    1 
ATOM   7233 N N      . VAL   F 1 341 ? 236.254 274.803 211.978 1.00 47.18  ? 353 VAL   A N      1 
ATOM   7234 C CA     . VAL   F 1 341 ? 236.527 274.289 210.639 1.00 44.10  ? 353 VAL   A CA     1 
ATOM   7235 C C      . VAL   F 1 341 ? 236.955 272.830 210.735 1.00 47.58  ? 353 VAL   A C      1 
ATOM   7236 O O      . VAL   F 1 341 ? 237.590 272.434 211.723 1.00 49.41  ? 353 VAL   A O      1 
ATOM   7237 C CB     . VAL   F 1 341 ? 237.598 275.133 209.932 1.00 44.48  ? 353 VAL   A CB     1 
ATOM   7238 C CG1    . VAL   F 1 341 ? 237.496 274.965 208.430 1.00 47.43  ? 353 VAL   A CG1    1 
ATOM   7239 C CG2    . VAL   F 1 341 ? 237.454 276.592 210.314 1.00 48.03  ? 353 VAL   A CG2    1 
ATOM   7240 N N      . PRO   F 1 342 ? 236.626 271.999 209.752 1.00 45.77  ? 354 PRO   A N      1 
ATOM   7241 C CA     . PRO   F 1 342 ? 237.097 270.611 209.766 1.00 44.72  ? 354 PRO   A CA     1 
ATOM   7242 C C      . PRO   F 1 342 ? 238.615 270.546 209.677 1.00 46.14  ? 354 PRO   A C      1 
ATOM   7243 O O      . PRO   F 1 342 ? 239.301 271.530 209.395 1.00 48.25  ? 354 PRO   A O      1 
ATOM   7244 C CB     . PRO   F 1 342 ? 236.431 269.988 208.535 1.00 42.23  ? 354 PRO   A CB     1 
ATOM   7245 C CG     . PRO   F 1 342 ? 236.016 271.144 207.687 1.00 41.65  ? 354 PRO   A CG     1 
ATOM   7246 C CD     . PRO   F 1 342 ? 235.720 272.266 208.624 1.00 42.77  ? 354 PRO   A CD     1 
ATOM   7247 N N      . ARG   F 1 343 ? 239.139 269.346 209.932 1.00 46.21  ? 355 ARG   A N      1 
ATOM   7248 C CA     . ARG   F 1 343 ? 240.587 269.160 209.954 1.00 46.36  ? 355 ARG   A CA     1 
ATOM   7249 C C      . ARG   F 1 343 ? 241.207 269.448 208.593 1.00 46.20  ? 355 ARG   A C      1 
ATOM   7250 O O      . ARG   F 1 343 ? 242.276 270.064 208.507 1.00 45.93  ? 355 ARG   A O      1 
ATOM   7251 C CB     . ARG   F 1 343 ? 240.924 267.741 210.407 1.00 44.59  ? 355 ARG   A CB     1 
ATOM   7252 C CG     . ARG   F 1 343 ? 242.409 267.453 210.510 1.00 43.38  ? 355 ARG   A CG     1 
ATOM   7253 C CD     . ARG   F 1 343 ? 243.068 268.307 211.573 1.00 42.84  ? 355 ARG   A CD     1 
ATOM   7254 N NE     . ARG   F 1 343 ? 244.462 267.935 211.780 1.00 45.93  ? 355 ARG   A NE     1 
ATOM   7255 C CZ     . ARG   F 1 343 ? 245.496 268.589 211.271 1.00 42.24  ? 355 ARG   A CZ     1 
ATOM   7256 N NH1    . ARG   F 1 343 ? 245.332 269.658 210.511 1.00 43.13  ? 355 ARG   A NH1    1 
ATOM   7257 N NH2    . ARG   F 1 343 ? 246.727 268.158 211.529 1.00 41.53  ? 355 ARG   A NH2    1 
ATOM   7258 N N      . GLY   F 1 344 ? 240.556 269.009 207.516 1.00 48.55  ? 356 GLY   A N      1 
ATOM   7259 C CA     . GLY   F 1 344 ? 241.129 269.194 206.195 1.00 50.09  ? 356 GLY   A CA     1 
ATOM   7260 C C      . GLY   F 1 344 ? 241.285 270.649 205.803 1.00 49.13  ? 356 GLY   A C      1 
ATOM   7261 O O      . GLY   F 1 344 ? 242.113 270.980 204.952 1.00 50.13  ? 356 GLY   A O      1 
ATOM   7262 N N      . LYS   F 1 345 ? 240.503 271.535 206.414 1.00 44.73  ? 357 LYS   A N      1 
ATOM   7263 C CA     . LYS   F 1 345 ? 240.524 272.951 206.083 1.00 45.53  ? 357 LYS   A CA     1 
ATOM   7264 C C      . LYS   F 1 345 ? 241.342 273.771 207.069 1.00 46.56  ? 357 LYS   A C      1 
ATOM   7265 O O      . LYS   F 1 345 ? 241.326 275.003 207.000 1.00 44.30  ? 357 LYS   A O      1 
ATOM   7266 C CB     . LYS   F 1 345 ? 239.097 273.490 206.007 1.00 44.99  ? 357 LYS   A CB     1 
ATOM   7267 C CG     . LYS   F 1 345 ? 238.372 273.101 204.737 1.00 45.56  ? 357 LYS   A CG     1 
ATOM   7268 C CD     . LYS   F 1 345 ? 237.201 274.018 204.467 1.00 49.02  ? 357 LYS   A CD     1 
ATOM   7269 C CE     . LYS   F 1 345 ? 236.651 273.778 203.078 1.00 59.53  ? 357 LYS   A CE     1 
ATOM   7270 N NZ     . LYS   F 1 345 ? 237.596 272.964 202.265 1.00 58.37  ? 357 LYS   A NZ     1 
ATOM   7271 N N      . LEU   F 1 346 ? 242.058 273.117 207.977 1.00 50.95  ? 358 LEU   A N      1 
ATOM   7272 C CA     . LEU   F 1 346 ? 242.880 273.798 208.968 1.00 47.41  ? 358 LEU   A CA     1 
ATOM   7273 C C      . LEU   F 1 346 ? 244.257 274.067 208.374 1.00 48.03  ? 358 LEU   A C      1 
ATOM   7274 O O      . LEU   F 1 346 ? 244.965 273.132 207.987 1.00 49.43  ? 358 LEU   A O      1 
ATOM   7275 C CB     . LEU   F 1 346 ? 243.002 272.952 210.234 1.00 46.13  ? 358 LEU   A CB     1 
ATOM   7276 C CG     . LEU   F 1 346 ? 241.951 273.142 211.326 1.00 46.22  ? 358 LEU   A CG     1 
ATOM   7277 C CD1    . LEU   F 1 346 ? 242.461 272.613 212.655 1.00 41.25  ? 358 LEU   A CD1    1 
ATOM   7278 C CD2    . LEU   F 1 346 ? 241.559 274.599 211.443 1.00 49.74  ? 358 LEU   A CD2    1 
ATOM   7279 N N      . SER   F 1 347 ? 244.636 275.340 208.308 1.00 47.76  ? 359 SER   A N      1 
ATOM   7280 C CA     . SER   F 1 347 ? 245.958 275.724 207.817 1.00 48.09  ? 359 SER   A CA     1 
ATOM   7281 C C      . SER   F 1 347 ? 246.957 275.773 208.974 1.00 51.16  ? 359 SER   A C      1 
ATOM   7282 O O      . SER   F 1 347 ? 247.504 276.815 209.328 1.00 58.02  ? 359 SER   A O      1 
ATOM   7283 C CB     . SER   F 1 347 ? 245.884 277.061 207.089 1.00 46.54  ? 359 SER   A CB     1 
ATOM   7284 O OG     . SER   F 1 347 ? 245.589 278.111 207.990 1.00 48.90  ? 359 SER   A OG     1 
ATOM   7285 N N      . THR   F 1 348 ? 247.180 274.606 209.573 1.00 48.94  ? 360 THR   A N      1 
ATOM   7286 C CA     . THR   F 1 348 ? 248.108 274.500 210.687 1.00 50.30  ? 360 THR   A CA     1 
ATOM   7287 C C      . THR   F 1 348 ? 248.601 273.066 210.795 1.00 49.99  ? 360 THR   A C      1 
ATOM   7288 O O      . THR   F 1 348 ? 247.920 272.127 210.376 1.00 51.30  ? 360 THR   A O      1 
ATOM   7289 C CB     . THR   F 1 348 ? 247.459 274.930 212.006 1.00 49.99  ? 360 THR   A CB     1 
ATOM   7290 O OG1    . THR   F 1 348 ? 248.373 274.697 213.084 1.00 56.71  ? 360 THR   A OG1    1 
ATOM   7291 C CG2    . THR   F 1 348 ? 246.193 274.133 212.253 1.00 50.24  ? 360 THR   A CG2    1 
ATOM   7292 N N      . ARG   F 1 349 ? 249.795 272.913 211.348 1.00 48.53  ? 361 ARG   A N      1 
ATOM   7293 C CA     . ARG   F 1 349 ? 250.337 271.614 211.697 1.00 48.73  ? 361 ARG   A CA     1 
ATOM   7294 C C      . ARG   F 1 349 ? 250.237 271.420 213.209 1.00 48.87  ? 361 ARG   A C      1 
ATOM   7295 O O      . ARG   F 1 349 ? 249.636 272.227 213.923 1.00 52.63  ? 361 ARG   A O      1 
ATOM   7296 C CB     . ARG   F 1 349 ? 251.769 271.487 211.176 1.00 50.48  ? 361 ARG   A CB     1 
ATOM   7297 C CG     . ARG   F 1 349 ? 251.843 271.133 209.701 1.00 46.87  ? 361 ARG   A CG     1 
ATOM   7298 C CD     . ARG   F 1 349 ? 253.205 271.430 209.105 1.00 45.41  ? 361 ARG   A CD     1 
ATOM   7299 N NE     . ARG   F 1 349 ? 254.296 271.059 209.996 1.00 51.08  ? 361 ARG   A NE     1 
ATOM   7300 C CZ     . ARG   F 1 349 ? 254.811 269.841 210.083 1.00 52.40  ? 361 ARG   A CZ     1 
ATOM   7301 N NH1    . ARG   F 1 349 ? 254.338 268.839 209.362 1.00 54.78  ? 361 ARG   A NH1    1 
ATOM   7302 N NH2    . ARG   F 1 349 ? 255.824 269.623 210.916 1.00 50.36  ? 361 ARG   A NH2    1 
ATOM   7303 N N      . GLY   F 1 350 ? 250.832 270.343 213.710 1.00 49.51  ? 362 GLY   A N      1 
ATOM   7304 C CA     . GLY   F 1 350 ? 250.736 270.048 215.124 1.00 48.84  ? 362 GLY   A CA     1 
ATOM   7305 C C      . GLY   F 1 350 ? 251.341 271.140 215.984 1.00 48.39  ? 362 GLY   A C      1 
ATOM   7306 O O      . GLY   F 1 350 ? 252.140 271.963 215.536 1.00 52.71  ? 362 GLY   A O      1 
ATOM   7307 N N      . VAL   F 1 351 ? 250.937 271.142 217.254 1.00 46.47  ? 363 VAL   A N      1 
ATOM   7308 C CA     . VAL   F 1 351 ? 251.419 272.157 218.185 1.00 47.04  ? 363 VAL   A CA     1 
ATOM   7309 C C      . VAL   F 1 351 ? 252.906 271.973 218.462 1.00 47.58  ? 363 VAL   A C      1 
ATOM   7310 O O      . VAL   F 1 351 ? 253.658 272.948 218.562 1.00 52.51  ? 363 VAL   A O      1 
ATOM   7311 C CB     . VAL   F 1 351 ? 250.592 272.123 219.483 1.00 44.61  ? 363 VAL   A CB     1 
ATOM   7312 C CG1    . VAL   F 1 351 ? 251.298 272.895 220.580 1.00 47.44  ? 363 VAL   A CG1    1 
ATOM   7313 C CG2    . VAL   F 1 351 ? 249.204 272.686 219.239 1.00 43.96  ? 363 VAL   A CG2    1 
ATOM   7314 N N      . GLN   F 1 352 ? 253.351 270.728 218.595 1.00 46.61  ? 364 GLN   A N      1 
ATOM   7315 C CA     . GLN   F 1 352 ? 254.740 270.457 218.935 1.00 46.30  ? 364 GLN   A CA     1 
ATOM   7316 C C      . GLN   F 1 352 ? 255.654 270.750 217.751 1.00 46.07  ? 364 GLN   A C      1 
ATOM   7317 O O      . GLN   F 1 352 ? 255.344 270.413 216.606 1.00 45.78  ? 364 GLN   A O      1 
ATOM   7318 C CB     . GLN   F 1 352 ? 254.893 269.003 219.376 1.00 49.10  ? 364 GLN   A CB     1 
ATOM   7319 C CG     . GLN   F 1 352 ? 255.091 268.830 220.868 1.00 51.62  ? 364 GLN   A CG     1 
ATOM   7320 C CD     . GLN   F 1 352 ? 254.938 267.393 221.309 1.00 57.31  ? 364 GLN   A CD     1 
ATOM   7321 O OE1    . GLN   F 1 352 ? 254.813 266.489 220.485 1.00 57.93  ? 364 GLN   A OE1    1 
ATOM   7322 N NE2    . GLN   F 1 352 ? 254.945 267.173 222.616 1.00 60.35  ? 364 GLN   A NE2    1 
ATOM   7323 N N      . ILE   F 1 353 ? 256.791 271.377 218.035 1.00 47.45  ? 365 ILE   A N      1 
ATOM   7324 C CA     . ILE   F 1 353 ? 257.755 271.766 217.012 1.00 51.88  ? 365 ILE   A CA     1 
ATOM   7325 C C      . ILE   F 1 353 ? 258.881 270.745 216.985 1.00 54.06  ? 365 ILE   A C      1 
ATOM   7326 O O      . ILE   F 1 353 ? 259.407 270.353 218.034 1.00 57.02  ? 365 ILE   A O      1 
ATOM   7327 C CB     . ILE   F 1 353 ? 258.297 273.184 217.267 1.00 52.45  ? 365 ILE   A CB     1 
ATOM   7328 C CG1    . ILE   F 1 353 ? 257.148 274.188 217.299 1.00 48.26  ? 365 ILE   A CG1    1 
ATOM   7329 C CG2    . ILE   F 1 353 ? 259.303 273.568 216.200 1.00 57.72  ? 365 ILE   A CG2    1 
ATOM   7330 C CD1    . ILE   F 1 353 ? 256.417 274.309 215.988 1.00 52.18  ? 365 ILE   A CD1    1 
ATOM   7331 N N      . ALA   F 1 354 ? 259.255 270.317 215.786 1.00 55.46  ? 366 ALA   A N      1 
ATOM   7332 C CA     . ALA   F 1 354 ? 260.250 269.274 215.603 1.00 57.02  ? 366 ALA   A CA     1 
ATOM   7333 C C      . ALA   F 1 354 ? 261.654 269.861 215.624 1.00 58.92  ? 366 ALA   A C      1 
ATOM   7334 O O      . ALA   F 1 354 ? 261.850 271.064 215.435 1.00 60.31  ? 366 ALA   A O      1 
ATOM   7335 C CB     . ALA   F 1 354 ? 260.021 268.526 214.290 1.00 57.20  ? 366 ALA   A CB     1 
ATOM   7336 N N      . SER   F 1 355 ? 262.637 268.990 215.855 1.00 58.06  ? 367 SER   A N      1 
ATOM   7337 C CA     . SER   F 1 355 ? 264.025 269.437 215.879 1.00 58.11  ? 367 SER   A CA     1 
ATOM   7338 C C      . SER   F 1 355 ? 264.458 269.981 214.523 1.00 60.34  ? 367 SER   A C      1 
ATOM   7339 O O      . SER   F 1 355 ? 265.186 270.978 214.452 1.00 60.11  ? 367 SER   A O      1 
ATOM   7340 C CB     . SER   F 1 355 ? 264.935 268.290 216.313 1.00 59.62  ? 367 SER   A CB     1 
ATOM   7341 O OG     . SER   F 1 355 ? 266.294 268.598 216.063 1.00 71.95  ? 367 SER   A OG     1 
ATOM   7342 N N      . ASN   F 1 356 ? 264.024 269.345 213.437 1.00 60.30  ? 368 ASN   A N      1 
ATOM   7343 C CA     . ASN   F 1 356 ? 264.496 269.703 212.105 1.00 58.54  ? 368 ASN   A CA     1 
ATOM   7344 C C      . ASN   F 1 356 ? 263.907 271.020 211.620 1.00 62.83  ? 368 ASN   A C      1 
ATOM   7345 O O      . ASN   F 1 356 ? 264.108 271.398 210.462 1.00 73.52  ? 368 ASN   A O      1 
ATOM   7346 C CB     . ASN   F 1 356 ? 264.164 268.595 211.106 1.00 54.80  ? 368 ASN   A CB     1 
ATOM   7347 C CG     . ASN   F 1 356 ? 262.674 268.438 210.884 1.00 53.93  ? 368 ASN   A CG     1 
ATOM   7348 O OD1    . ASN   F 1 356 ? 262.054 269.232 210.177 1.00 56.52  ? 368 ASN   A OD1    1 
ATOM   7349 N ND2    . ASN   F 1 356 ? 262.090 267.415 211.490 1.00 54.90  ? 368 ASN   A ND2    1 
ATOM   7350 N N      . GLU   F 1 357 ? 263.182 271.726 212.481 1.00 56.70  ? 369 GLU   A N      1 
ATOM   7351 C CA     . GLU   F 1 357 ? 262.501 272.958 212.104 1.00 58.46  ? 369 GLU   A CA     1 
ATOM   7352 C C      . GLU   F 1 357 ? 263.356 274.149 212.508 1.00 58.03  ? 369 GLU   A C      1 
ATOM   7353 O O      . GLU   F 1 357 ? 263.814 274.229 213.651 1.00 61.12  ? 369 GLU   A O      1 
ATOM   7354 C CB     . GLU   F 1 357 ? 261.123 273.046 212.764 1.00 60.44  ? 369 GLU   A CB     1 
ATOM   7355 C CG     . GLU   F 1 357 ? 260.121 272.037 212.234 1.00 58.40  ? 369 GLU   A CG     1 
ATOM   7356 C CD     . GLU   F 1 357 ? 258.758 272.643 211.991 1.00 56.58  ? 369 GLU   A CD     1 
ATOM   7357 O OE1    . GLU   F 1 357 ? 258.681 273.868 211.783 1.00 60.73  ? 369 GLU   A OE1    1 
ATOM   7358 O OE2    . GLU   F 1 357 ? 257.763 271.891 212.007 1.00 58.33  ? 369 GLU   A OE2    1 
ATOM   7359 N N      . ASN   F 1 358 ? 263.573 275.068 211.572 1.00 56.96  ? 370 ASN   A N      1 
ATOM   7360 C CA     . ASN   F 1 358 ? 264.409 276.236 211.839 1.00 64.90  ? 370 ASN   A CA     1 
ATOM   7361 C C      . ASN   F 1 358 ? 263.705 277.160 212.829 1.00 63.63  ? 370 ASN   A C      1 
ATOM   7362 O O      . ASN   F 1 358 ? 262.731 277.838 212.503 1.00 61.27  ? 370 ASN   A O      1 
ATOM   7363 C CB     . ASN   F 1 358 ? 264.794 276.936 210.536 1.00 64.15  ? 370 ASN   A CB     1 
ATOM   7364 C CG     . ASN   F 1 358 ? 263.630 277.632 209.849 1.00 67.78  ? 370 ASN   A CG     1 
ATOM   7365 O OD1    . ASN   F 1 358 ? 262.482 277.545 210.274 1.00 71.69  ? 370 ASN   A OD1    1 
ATOM   7366 N ND2    . ASN   F 1 358 ? 263.937 278.342 208.772 1.00 64.67  ? 370 ASN   A ND2    1 
ATOM   7367 N N      . MET   F 1 359 ? 264.201 277.180 214.063 1.00 65.28  ? 371 MET   A N      1 
ATOM   7368 C CA     . MET   F 1 359 ? 263.552 277.948 215.116 1.00 64.65  ? 371 MET   A CA     1 
ATOM   7369 C C      . MET   F 1 359 ? 263.989 279.404 215.036 1.00 66.40  ? 371 MET   A C      1 
ATOM   7370 O O      . MET   F 1 359 ? 264.436 279.984 216.030 1.00 75.03  ? 371 MET   A O      1 
ATOM   7371 C CB     . MET   F 1 359 ? 263.877 277.344 216.484 1.00 56.47  ? 371 MET   A CB     1 
ATOM   7372 C CG     . MET   F 1 359 ? 262.663 276.829 217.243 1.00 52.59  ? 371 MET   A CG     1 
ATOM   7373 S SD     . MET   F 1 359 ? 261.611 278.141 217.876 1.00 73.77  ? 371 MET   A SD     1 
ATOM   7374 C CE     . MET   F 1 359 ? 262.644 278.749 219.200 1.00 64.94  ? 371 MET   A CE     1 
ATOM   7375 N N      . GLU   F 1 360 ? 263.852 279.999 213.851 1.00 60.64  ? 372 GLU   A N      1 
ATOM   7376 C CA     . GLU   F 1 360 ? 264.227 281.387 213.622 1.00 67.85  ? 372 GLU   A CA     1 
ATOM   7377 C C      . GLU   F 1 360 ? 263.194 282.186 212.846 1.00 71.50  ? 372 GLU   A C      1 
ATOM   7378 O O      . GLU   F 1 360 ? 263.164 283.414 212.986 1.00 76.43  ? 372 GLU   A O      1 
ATOM   7379 C CB     . GLU   F 1 360 ? 265.567 281.466 212.878 1.00 70.62  ? 372 GLU   A CB     1 
ATOM   7380 C CG     . GLU   F 1 360 ? 265.849 282.825 212.276 1.00 74.45  ? 372 GLU   A CG     1 
ATOM   7381 C CD     . GLU   F 1 360 ? 267.203 283.362 212.688 1.00 88.81  ? 372 GLU   A CD     1 
ATOM   7382 O OE1    . GLU   F 1 360 ? 267.315 284.585 212.916 1.00 95.25  ? 372 GLU   A OE1    1 
ATOM   7383 O OE2    . GLU   F 1 360 ? 268.157 282.564 212.793 1.00 91.85  ? 372 GLU   A OE2    1 
ATOM   7384 N N      . THR   F 1 361 ? 262.352 281.544 212.043 1.00 69.27  ? 373 THR   A N      1 
ATOM   7385 C CA     . THR   F 1 361 ? 261.241 282.205 211.379 1.00 67.32  ? 373 THR   A CA     1 
ATOM   7386 C C      . THR   F 1 361 ? 259.931 282.005 212.126 1.00 62.98  ? 373 THR   A C      1 
ATOM   7387 O O      . THR   F 1 361 ? 258.862 282.241 211.556 1.00 66.78  ? 373 THR   A O      1 
ATOM   7388 C CB     . THR   F 1 361 ? 261.103 281.696 209.945 1.00 67.69  ? 373 THR   A CB     1 
ATOM   7389 O OG1    . THR   F 1 361 ? 260.628 280.345 209.964 1.00 73.15  ? 373 THR   A OG1    1 
ATOM   7390 C CG2    . THR   F 1 361 ? 262.445 281.734 209.241 1.00 70.58  ? 373 THR   A CG2    1 
ATOM   7391 N N      . MET   F 1 362 ? 259.991 281.569 213.379 1.00 58.35  ? 374 MET   A N      1 
ATOM   7392 C CA     . MET   F 1 362 ? 258.807 281.243 214.161 1.00 57.49  ? 374 MET   A CA     1 
ATOM   7393 C C      . MET   F 1 362 ? 258.430 282.423 215.045 1.00 54.71  ? 374 MET   A C      1 
ATOM   7394 O O      . MET   F 1 362 ? 259.276 282.961 215.765 1.00 58.42  ? 374 MET   A O      1 
ATOM   7395 C CB     . MET   F 1 362 ? 259.050 280.000 215.018 1.00 56.62  ? 374 MET   A CB     1 
ATOM   7396 C CG     . MET   F 1 362 ? 257.915 278.996 214.995 1.00 54.34  ? 374 MET   A CG     1 
ATOM   7397 S SD     . MET   F 1 362 ? 258.501 277.301 215.148 1.00 60.28  ? 374 MET   A SD     1 
ATOM   7398 C CE     . MET   F 1 362 ? 258.967 276.953 213.458 1.00 59.88  ? 374 MET   A CE     1 
ATOM   7399 N N      . GLU   F 1 363 ? 257.164 282.822 214.988 1.00 52.40  ? 375 GLU   A N      1 
ATOM   7400 C CA     . GLU   F 1 363 ? 256.640 283.870 215.847 1.00 53.69  ? 375 GLU   A CA     1 
ATOM   7401 C C      . GLU   F 1 363 ? 255.543 283.302 216.736 1.00 52.70  ? 375 GLU   A C      1 
ATOM   7402 O O      . GLU   F 1 363 ? 254.980 282.240 216.457 1.00 52.84  ? 375 GLU   A O      1 
ATOM   7403 C CB     . GLU   F 1 363 ? 256.096 285.058 215.040 1.00 55.60  ? 375 GLU   A CB     1 
ATOM   7404 C CG     . GLU   F 1 363 ? 255.043 284.709 214.003 1.00 56.68  ? 375 GLU   A CG     1 
ATOM   7405 C CD     . GLU   F 1 363 ? 255.622 284.072 212.762 1.00 57.42  ? 375 GLU   A CD     1 
ATOM   7406 O OE1    . GLU   F 1 363 ? 256.656 283.383 212.873 1.00 62.70  ? 375 GLU   A OE1    1 
ATOM   7407 O OE2    . GLU   F 1 363 ? 255.042 284.263 211.674 1.00 54.50  ? 375 GLU   A OE2    1 
ATOM   7408 N N      . SER   F 1 364 ? 255.251 284.021 217.814 1.00 53.00  ? 376 SER   A N      1 
ATOM   7409 C CA     . SER   F 1 364 ? 254.295 283.585 218.820 1.00 55.23  ? 376 SER   A CA     1 
ATOM   7410 C C      . SER   F 1 364 ? 253.001 284.377 218.701 1.00 58.15  ? 376 SER   A C      1 
ATOM   7411 O O      . SER   F 1 364 ? 253.011 285.551 218.323 1.00 61.47  ? 376 SER   A O      1 
ATOM   7412 C CB     . SER   F 1 364 ? 254.881 283.745 220.223 1.00 53.75  ? 376 SER   A CB     1 
ATOM   7413 O OG     . SER   F 1 364 ? 254.963 285.111 220.588 1.00 53.42  ? 376 SER   A OG     1 
ATOM   7414 N N      . SER   F 1 365 ? 251.886 283.723 219.016 1.00 55.41  ? 377 SER   A N      1 
ATOM   7415 C CA     . SER   F 1 365 ? 250.574 284.350 218.992 1.00 51.01  ? 377 SER   A CA     1 
ATOM   7416 C C      . SER   F 1 365 ? 249.787 283.948 220.231 1.00 49.90  ? 377 SER   A C      1 
ATOM   7417 O O      . SER   F 1 365 ? 250.032 282.898 220.828 1.00 51.96  ? 377 SER   A O      1 
ATOM   7418 C CB     . SER   F 1 365 ? 249.797 283.964 217.731 1.00 50.55  ? 377 SER   A CB     1 
ATOM   7419 O OG     . SER   F 1 365 ? 249.248 282.665 217.857 1.00 55.66  ? 377 SER   A OG     1 
ATOM   7420 N N      . THR   F 1 366 ? 248.845 284.803 220.618 1.00 48.87  ? 378 THR   A N      1 
ATOM   7421 C CA     . THR   F 1 366 ? 247.962 284.490 221.733 1.00 50.75  ? 378 THR   A CA     1 
ATOM   7422 C C      . THR   F 1 366 ? 246.856 283.540 221.289 1.00 48.26  ? 378 THR   A C      1 
ATOM   7423 O O      . THR   F 1 366 ? 246.224 283.738 220.248 1.00 47.64  ? 378 THR   A O      1 
ATOM   7424 C CB     . THR   F 1 366 ? 247.355 285.769 222.308 1.00 51.11  ? 378 THR   A CB     1 
ATOM   7425 O OG1    . THR   F 1 366 ? 248.363 286.781 222.390 1.00 50.39  ? 378 THR   A OG1    1 
ATOM   7426 C CG2    . THR   F 1 366 ? 246.796 285.515 223.694 1.00 50.74  ? 378 THR   A CG2    1 
ATOM   7427 N N      . LEU   F 1 367 ? 246.624 282.500 222.085 1.00 49.72  ? 379 LEU   A N      1 
ATOM   7428 C CA     . LEU   F 1 367 ? 245.588 281.519 221.795 1.00 50.58  ? 379 LEU   A CA     1 
ATOM   7429 C C      . LEU   F 1 367 ? 244.244 282.005 222.321 1.00 50.20  ? 379 LEU   A C      1 
ATOM   7430 O O      . LEU   F 1 367 ? 244.134 282.407 223.484 1.00 50.09  ? 379 LEU   A O      1 
ATOM   7431 C CB     . LEU   F 1 367 ? 245.930 280.163 222.411 1.00 49.06  ? 379 LEU   A CB     1 
ATOM   7432 C CG     . LEU   F 1 367 ? 247.182 279.444 221.910 1.00 49.25  ? 379 LEU   A CG     1 
ATOM   7433 C CD1    . LEU   F 1 367 ? 247.506 278.259 222.800 1.00 49.01  ? 379 LEU   A CD1    1 
ATOM   7434 C CD2    . LEU   F 1 367 ? 247.000 278.997 220.475 1.00 50.37  ? 379 LEU   A CD2    1 
ATOM   7435 N N      . GLU   F 1 368 ? 243.224 281.963 221.463 1.00 53.21  ? 380 GLU   A N      1 
ATOM   7436 C CA     . GLU   F 1 368 ? 241.865 282.353 221.841 1.00 52.27  ? 380 GLU   A CA     1 
ATOM   7437 C C      . GLU   F 1 368 ? 241.109 281.108 222.295 1.00 48.79  ? 380 GLU   A C      1 
ATOM   7438 O O      . GLU   F 1 368 ? 240.408 280.446 221.529 1.00 49.00  ? 380 GLU   A O      1 
ATOM   7439 C CB     . GLU   F 1 368 ? 241.165 283.048 220.682 1.00 53.89  ? 380 GLU   A CB     1 
ATOM   7440 C CG     . GLU   F 1 368 ? 242.033 284.058 219.963 1.00 65.35  ? 380 GLU   A CG     1 
ATOM   7441 C CD     . GLU   F 1 368 ? 241.297 284.758 218.843 1.00 82.05  ? 380 GLU   A CD     1 
ATOM   7442 O OE1    . GLU   F 1 368 ? 240.082 284.996 218.989 1.00 86.64  ? 380 GLU   A OE1    1 
ATOM   7443 O OE2    . GLU   F 1 368 ? 241.935 285.071 217.816 1.00 88.38  ? 380 GLU   A OE2    1 
ATOM   7444 N N      . LEU   F 1 369 ? 241.265 280.791 223.575 1.00 49.92  ? 381 LEU   A N      1 
ATOM   7445 C CA     . LEU   F 1 369 ? 240.650 279.604 224.165 1.00 51.89  ? 381 LEU   A CA     1 
ATOM   7446 C C      . LEU   F 1 369 ? 239.388 279.957 224.947 1.00 53.93  ? 381 LEU   A C      1 
ATOM   7447 O O      . LEU   F 1 369 ? 239.062 279.333 225.955 1.00 57.15  ? 381 LEU   A O      1 
ATOM   7448 C CB     . LEU   F 1 369 ? 241.659 278.889 225.055 1.00 49.79  ? 381 LEU   A CB     1 
ATOM   7449 C CG     . LEU   F 1 369 ? 242.985 278.483 224.416 1.00 47.05  ? 381 LEU   A CG     1 
ATOM   7450 C CD1    . LEU   F 1 369 ? 243.866 277.773 225.427 1.00 45.23  ? 381 LEU   A CD1    1 
ATOM   7451 C CD2    . LEU   F 1 369 ? 242.745 277.608 223.205 1.00 49.20  ? 381 LEU   A CD2    1 
ATOM   7452 N N      . ARG   F 1 370 ? 238.659 280.964 224.481 1.00 51.70  ? 382 ARG   A N      1 
ATOM   7453 C CA     . ARG   F 1 370 ? 237.465 281.441 225.161 1.00 49.49  ? 382 ARG   A CA     1 
ATOM   7454 C C      . ARG   F 1 370 ? 236.229 281.049 224.367 1.00 47.88  ? 382 ARG   A C      1 
ATOM   7455 O O      . ARG   F 1 370 ? 236.198 281.181 223.140 1.00 49.97  ? 382 ARG   A O      1 
ATOM   7456 C CB     . ARG   F 1 370 ? 237.498 282.959 225.359 1.00 49.63  ? 382 ARG   A CB     1 
ATOM   7457 C CG     . ARG   F 1 370 ? 238.001 283.738 224.161 1.00 58.05  ? 382 ARG   A CG     1 
ATOM   7458 C CD     . ARG   F 1 370 ? 238.773 284.966 224.600 1.00 59.21  ? 382 ARG   A CD     1 
ATOM   7459 N NE     . ARG   F 1 370 ? 237.891 285.971 225.179 1.00 56.00  ? 382 ARG   A NE     1 
ATOM   7460 C CZ     . ARG   F 1 370 ? 237.715 286.149 226.480 1.00 58.25  ? 382 ARG   A CZ     1 
ATOM   7461 N NH1    . ARG   F 1 370 ? 238.350 285.406 227.371 1.00 58.18  ? 382 ARG   A NH1    1 
ATOM   7462 N NH2    . ARG   F 1 370 ? 236.880 287.095 226.899 1.00 61.34  ? 382 ARG   A NH2    1 
ATOM   7463 N N      . SER   F 1 371 ? 235.212 280.571 225.074 1.00 46.02  ? 383 SER   A N      1 
ATOM   7464 C CA     . SER   F 1 371 ? 233.981 280.095 224.466 1.00 45.45  ? 383 SER   A CA     1 
ATOM   7465 C C      . SER   F 1 371 ? 232.829 281.008 224.855 1.00 44.42  ? 383 SER   A C      1 
ATOM   7466 O O      . SER   F 1 371 ? 232.766 281.500 225.985 1.00 47.96  ? 383 SER   A O      1 
ATOM   7467 C CB     . SER   F 1 371 ? 233.679 278.657 224.891 1.00 47.56  ? 383 SER   A CB     1 
ATOM   7468 O OG     . SER   F 1 371 ? 233.993 278.458 226.256 1.00 51.37  ? 383 SER   A OG     1 
ATOM   7469 N N      . ARG   F 1 372 ? 231.925 281.242 223.904 1.00 44.43  ? 384 ARG   A N      1 
ATOM   7470 C CA     . ARG   F 1 372 ? 230.752 282.061 224.186 1.00 45.86  ? 384 ARG   A CA     1 
ATOM   7471 C C      . ARG   F 1 372 ? 229.803 281.355 225.146 1.00 46.84  ? 384 ARG   A C      1 
ATOM   7472 O O      . ARG   F 1 372 ? 229.168 281.999 225.989 1.00 45.62  ? 384 ARG   A O      1 
ATOM   7473 C CB     . ARG   F 1 372 ? 230.039 282.412 222.882 1.00 46.02  ? 384 ARG   A CB     1 
ATOM   7474 C CG     . ARG   F 1 372 ? 228.637 282.942 223.065 1.00 48.37  ? 384 ARG   A CG     1 
ATOM   7475 C CD     . ARG   F 1 372 ? 228.092 283.517 221.772 1.00 49.86  ? 384 ARG   A CD     1 
ATOM   7476 N NE     . ARG   F 1 372 ? 226.750 284.074 221.908 1.00 56.94  ? 384 ARG   A NE     1 
ATOM   7477 C CZ     . ARG   F 1 372 ? 226.318 284.795 222.935 1.00 65.68  ? 384 ARG   A CZ     1 
ATOM   7478 N NH1    . ARG   F 1 372 ? 227.113 285.121 223.941 1.00 63.17  ? 384 ARG   A NH1    1 
ATOM   7479 N NH2    . ARG   F 1 372 ? 225.056 285.213 222.946 1.00 71.60  ? 384 ARG   A NH2    1 
ATOM   7480 N N      . TYR   F 1 373 ? 229.694 280.040 225.035 1.00 48.05  ? 385 TYR   A N      1 
ATOM   7481 C CA     . TYR   F 1 373 ? 228.815 279.243 225.877 1.00 46.29  ? 385 TYR   A CA     1 
ATOM   7482 C C      . TYR   F 1 373 ? 229.625 278.153 226.577 1.00 48.51  ? 385 TYR   A C      1 
ATOM   7483 O O      . TYR   F 1 373 ? 230.815 277.967 226.316 1.00 52.27  ? 385 TYR   A O      1 
ATOM   7484 C CB     . TYR   F 1 373 ? 227.679 278.650 225.043 1.00 47.39  ? 385 TYR   A CB     1 
ATOM   7485 C CG     . TYR   F 1 373 ? 226.660 279.657 224.566 1.00 47.35  ? 385 TYR   A CG     1 
ATOM   7486 C CD1    . TYR   F 1 373 ? 225.933 280.417 225.468 1.00 50.34  ? 385 TYR   A CD1    1 
ATOM   7487 C CD2    . TYR   F 1 373 ? 226.420 279.843 223.213 1.00 48.54  ? 385 TYR   A CD2    1 
ATOM   7488 C CE1    . TYR   F 1 373 ? 224.999 281.334 225.038 1.00 50.60  ? 385 TYR   A CE1    1 
ATOM   7489 C CE2    . TYR   F 1 373 ? 225.488 280.759 222.774 1.00 49.17  ? 385 TYR   A CE2    1 
ATOM   7490 C CZ     . TYR   F 1 373 ? 224.781 281.502 223.691 1.00 49.63  ? 385 TYR   A CZ     1 
ATOM   7491 O OH     . TYR   F 1 373 ? 223.851 282.416 223.259 1.00 55.58  ? 385 TYR   A OH     1 
ATOM   7492 N N      . TRP   F 1 374 ? 228.965 277.428 227.477 1.00 48.76  ? 386 TRP   A N      1 
ATOM   7493 C CA     . TRP   F 1 374 ? 229.591 276.311 228.165 1.00 49.90  ? 386 TRP   A CA     1 
ATOM   7494 C C      . TRP   F 1 374 ? 228.561 275.209 228.356 1.00 50.22  ? 386 TRP   A C      1 
ATOM   7495 O O      . TRP   F 1 374 ? 227.390 275.483 228.627 1.00 52.97  ? 386 TRP   A O      1 
ATOM   7496 C CB     . TRP   F 1 374 ? 230.195 276.740 229.510 1.00 49.15  ? 386 TRP   A CB     1 
ATOM   7497 C CG     . TRP   F 1 374 ? 229.231 276.797 230.656 1.00 49.03  ? 386 TRP   A CG     1 
ATOM   7498 C CD1    . TRP   F 1 374 ? 228.497 277.874 231.055 1.00 53.45  ? 386 TRP   A CD1    1 
ATOM   7499 C CD2    . TRP   F 1 374 ? 228.920 275.740 231.572 1.00 50.36  ? 386 TRP   A CD2    1 
ATOM   7500 N NE1    . TRP   F 1 374 ? 227.739 277.551 232.152 1.00 53.51  ? 386 TRP   A NE1    1 
ATOM   7501 C CE2    . TRP   F 1 374 ? 227.981 276.246 232.489 1.00 52.05  ? 386 TRP   A CE2    1 
ATOM   7502 C CE3    . TRP   F 1 374 ? 229.339 274.413 231.699 1.00 50.11  ? 386 TRP   A CE3    1 
ATOM   7503 C CZ2    . TRP   F 1 374 ? 227.453 275.472 233.518 1.00 51.86  ? 386 TRP   A CZ2    1 
ATOM   7504 C CZ3    . TRP   F 1 374 ? 228.815 273.649 232.720 1.00 49.07  ? 386 TRP   A CZ3    1 
ATOM   7505 C CH2    . TRP   F 1 374 ? 227.883 274.179 233.616 1.00 50.39  ? 386 TRP   A CH2    1 
ATOM   7506 N N      . ALA   F 1 375 ? 229.007 273.965 228.203 1.00 49.18  ? 387 ALA   A N      1 
ATOM   7507 C CA     . ALA   F 1 375 ? 228.139 272.805 228.320 1.00 50.94  ? 387 ALA   A CA     1 
ATOM   7508 C C      . ALA   F 1 375 ? 228.791 271.785 229.242 1.00 49.60  ? 387 ALA   A C      1 
ATOM   7509 O O      . ALA   F 1 375 ? 229.979 271.874 229.561 1.00 50.45  ? 387 ALA   A O      1 
ATOM   7510 C CB     . ALA   F 1 375 ? 227.844 272.177 226.954 1.00 48.55  ? 387 ALA   A CB     1 
ATOM   7511 N N      . ILE   F 1 376 ? 227.993 270.819 229.678 1.00 46.40  ? 388 ILE   A N      1 
ATOM   7512 C CA     . ILE   F 1 376 ? 228.456 269.776 230.584 1.00 46.64  ? 388 ILE   A CA     1 
ATOM   7513 C C      . ILE   F 1 376 ? 228.897 268.570 229.767 1.00 48.54  ? 388 ILE   A C      1 
ATOM   7514 O O      . ILE   F 1 376 ? 228.145 268.072 228.921 1.00 49.09  ? 388 ILE   A O      1 
ATOM   7515 C CB     . ILE   F 1 376 ? 227.356 269.393 231.586 1.00 46.60  ? 388 ILE   A CB     1 
ATOM   7516 C CG1    . ILE   F 1 376 ? 227.078 270.554 232.538 1.00 46.77  ? 388 ILE   A CG1    1 
ATOM   7517 C CG2    . ILE   F 1 376 ? 227.759 268.156 232.365 1.00 49.51  ? 388 ILE   A CG2    1 
ATOM   7518 C CD1    . ILE   F 1 376 ? 225.716 270.500 233.175 1.00 48.96  ? 388 ILE   A CD1    1 
ATOM   7519 N N      . ARG   F 1 377 ? 230.115 268.102 230.017 1.00 49.52  ? 389 ARG   A N      1 
ATOM   7520 C CA     . ARG   F 1 377 ? 230.637 266.944 229.309 1.00 47.64  ? 389 ARG   A CA     1 
ATOM   7521 C C      . ARG   F 1 377 ? 229.901 265.678 229.736 1.00 46.08  ? 389 ARG   A C      1 
ATOM   7522 O O      . ARG   F 1 377 ? 229.529 265.509 230.899 1.00 47.34  ? 389 ARG   A O      1 
ATOM   7523 C CB     . ARG   F 1 377 ? 232.136 266.802 229.562 1.00 47.10  ? 389 ARG   A CB     1 
ATOM   7524 C CG     . ARG   F 1 377 ? 232.998 267.560 228.571 1.00 45.47  ? 389 ARG   A CG     1 
ATOM   7525 C CD     . ARG   F 1 377 ? 232.926 269.054 228.813 1.00 44.96  ? 389 ARG   A CD     1 
ATOM   7526 N NE     . ARG   F 1 377 ? 233.704 269.472 229.971 1.00 45.93  ? 389 ARG   A NE     1 
ATOM   7527 C CZ     . ARG   F 1 377 ? 233.481 270.586 230.654 1.00 45.58  ? 389 ARG   A CZ     1 
ATOM   7528 N NH1    . ARG   F 1 377 ? 232.496 271.406 230.332 1.00 44.53  ? 389 ARG   A NH1    1 
ATOM   7529 N NH2    . ARG   F 1 377 ? 234.263 270.882 231.686 1.00 50.74  ? 389 ARG   A NH2    1 
ATOM   7530 N N      . THR   F 1 378 ? 229.697 264.780 228.778 1.00 47.51  ? 390 THR   A N      1 
ATOM   7531 C CA     . THR   F 1 378 ? 228.860 263.607 228.971 1.00 50.85  ? 390 THR   A CA     1 
ATOM   7532 C C      . THR   F 1 378 ? 229.691 262.336 228.896 1.00 52.82  ? 390 THR   A C      1 
ATOM   7533 O O      . THR   F 1 378 ? 230.649 262.249 228.123 1.00 53.39  ? 390 THR   A O      1 
ATOM   7534 C CB     . THR   F 1 378 ? 227.747 263.538 227.922 1.00 53.64  ? 390 THR   A CB     1 
ATOM   7535 O OG1    . THR   F 1 378 ? 228.242 262.898 226.742 1.00 55.48  ? 390 THR   A OG1    1 
ATOM   7536 C CG2    . THR   F 1 378 ? 227.277 264.930 227.562 1.00 56.67  ? 390 THR   A CG2    1 
ATOM   7537 N N      . ARG   F 1 379 ? 229.319 261.356 229.713 1.00 54.35  ? 391 ARG   A N      1 
ATOM   7538 C CA     . ARG   F 1 379 ? 229.873 260.014 229.639 1.00 56.35  ? 391 ARG   A CA     1 
ATOM   7539 C C      . ARG   F 1 379 ? 228.943 259.051 228.916 1.00 58.22  ? 391 ARG   A C      1 
ATOM   7540 O O      . ARG   F 1 379 ? 229.184 257.841 228.933 1.00 63.36  ? 391 ARG   A O      1 
ATOM   7541 C CB     . ARG   F 1 379 ? 230.180 259.492 231.043 1.00 57.07  ? 391 ARG   A CB     1 
ATOM   7542 C CG     . ARG   F 1 379 ? 228.949 259.177 231.867 1.00 61.78  ? 391 ARG   A CG     1 
ATOM   7543 C CD     . ARG   F 1 379 ? 229.317 258.874 233.307 1.00 66.50  ? 391 ARG   A CD     1 
ATOM   7544 N NE     . ARG   F 1 379 ? 230.285 257.790 233.399 1.00 74.15  ? 391 ARG   A NE     1 
ATOM   7545 C CZ     . ARG   F 1 379 ? 231.422 257.859 234.077 1.00 92.53  ? 391 ARG   A CZ     1 
ATOM   7546 N NH1    . ARG   F 1 379 ? 231.764 258.949 234.744 1.00 92.89  ? 391 ARG   A NH1    1 
ATOM   7547 N NH2    . ARG   F 1 379 ? 232.237 256.807 234.085 1.00 97.12  ? 391 ARG   A NH2    1 
ATOM   7548 N N      . SER   F 1 380 ? 227.892 259.562 228.284 1.00 54.33  ? 392 SER   A N      1 
ATOM   7549 C CA     . SER   F 1 380 ? 226.871 258.746 227.649 1.00 57.59  ? 392 SER   A CA     1 
ATOM   7550 C C      . SER   F 1 380 ? 226.874 258.953 226.141 1.00 56.32  ? 392 SER   A C      1 
ATOM   7551 O O      . SER   F 1 380 ? 227.421 259.928 225.623 1.00 59.92  ? 392 SER   A O      1 
ATOM   7552 C CB     . SER   F 1 380 ? 225.484 259.074 228.210 1.00 57.27  ? 392 SER   A CB     1 
ATOM   7553 O OG     . SER   F 1 380 ? 224.798 259.978 227.363 1.00 52.22  ? 392 SER   A OG     1 
ATOM   7554 N N      . GLY   F 1 381 ? 226.252 258.009 225.442 1.00 53.66  ? 393 GLY   A N      1 
ATOM   7555 C CA     . GLY   F 1 381 ? 226.035 258.145 224.017 1.00 50.86  ? 393 GLY   A CA     1 
ATOM   7556 C C      . GLY   F 1 381 ? 224.742 258.879 223.735 1.00 57.66  ? 393 GLY   A C      1 
ATOM   7557 O O      . GLY   F 1 381 ? 224.503 259.955 224.289 1.00 68.87  ? 393 GLY   A O      1 
ATOM   7558 N N      . GLY   F 1 382 ? 223.894 258.307 222.890 1.00 54.58  ? 394 GLY   A N      1 
ATOM   7559 C CA     . GLY   F 1 382 ? 222.613 258.913 222.589 1.00 55.29  ? 394 GLY   A CA     1 
ATOM   7560 C C      . GLY   F 1 382 ? 221.457 258.092 223.118 1.00 58.61  ? 394 GLY   A C      1 
ATOM   7561 O O      . GLY   F 1 382 ? 221.153 258.131 224.312 1.00 59.07  ? 394 GLY   A O      1 
ATOM   7562 N N      . ASN   F 1 383 ? 220.803 257.350 222.232 1.00 62.51  ? 395 ASN   A N      1 
ATOM   7563 C CA     . ASN   F 1 383 ? 219.752 256.423 222.630 1.00 57.02  ? 395 ASN   A CA     1 
ATOM   7564 C C      . ASN   F 1 383 ? 219.982 255.051 222.003 1.00 54.84  ? 395 ASN   A C      1 
ATOM   7565 O O      . ASN   F 1 383 ? 219.173 254.138 222.165 1.00 48.29  ? 395 ASN   A O      1 
ATOM   7566 C CB     . ASN   F 1 383 ? 218.380 256.965 222.235 1.00 57.65  ? 395 ASN   A CB     1 
ATOM   7567 C CG     . ASN   F 1 383 ? 217.853 257.983 223.223 1.00 61.91  ? 395 ASN   A CG     1 
ATOM   7568 O OD1    . ASN   F 1 383 ? 218.570 258.427 224.116 1.00 60.78  ? 395 ASN   A OD1    1 
ATOM   7569 N ND2    . ASN   F 1 383 ? 216.589 258.356 223.068 1.00 70.70  ? 395 ASN   A ND2    1 
ATOM   7570 N N      . MET   F 1 428 ? 222.243 238.886 219.938 1.00 51.21  ? 440 MET   A N      1 
ATOM   7571 C CA     . MET   F 1 428 ? 223.440 238.367 219.285 1.00 49.88  ? 440 MET   A CA     1 
ATOM   7572 C C      . MET   F 1 428 ? 223.922 239.288 218.159 1.00 52.30  ? 440 MET   A C      1 
ATOM   7573 O O      . MET   F 1 428 ? 224.416 240.382 218.425 1.00 61.48  ? 440 MET   A O      1 
ATOM   7574 C CB     . MET   F 1 428 ? 223.185 236.947 218.766 1.00 51.47  ? 440 MET   A CB     1 
ATOM   7575 C CG     . MET   F 1 428 ? 222.049 236.806 217.767 1.00 53.11  ? 440 MET   A CG     1 
ATOM   7576 S SD     . MET   F 1 428 ? 222.057 235.187 216.979 1.00 66.85  ? 440 MET   A SD     1 
ATOM   7577 C CE     . MET   F 1 428 ? 223.816 234.856 216.921 1.00 40.31  ? 440 MET   A CE     1 
ATOM   7578 N N      . ARG   F 1 429 ? 223.781 238.860 216.917 1.00 51.48  ? 441 ARG   A N      1 
ATOM   7579 C CA     . ARG   F 1 429 ? 224.276 239.639 215.788 1.00 51.00  ? 441 ARG   A CA     1 
ATOM   7580 C C      . ARG   F 1 429 ? 223.173 240.094 214.845 1.00 50.85  ? 441 ARG   A C      1 
ATOM   7581 O O      . ARG   F 1 429 ? 223.233 241.215 214.338 1.00 50.57  ? 441 ARG   A O      1 
ATOM   7582 C CB     . ARG   F 1 429 ? 225.321 238.827 215.009 1.00 48.02  ? 441 ARG   A CB     1 
ATOM   7583 C CG     . ARG   F 1 429 ? 226.227 239.667 214.133 1.00 50.12  ? 441 ARG   A CG     1 
ATOM   7584 C CD     . ARG   F 1 429 ? 226.992 238.808 213.147 1.00 50.94  ? 441 ARG   A CD     1 
ATOM   7585 N NE     . ARG   F 1 429 ? 228.207 238.254 213.731 1.00 57.15  ? 441 ARG   A NE     1 
ATOM   7586 C CZ     . ARG   F 1 429 ? 229.401 238.302 213.158 1.00 58.27  ? 441 ARG   A CZ     1 
ATOM   7587 N NH1    . ARG   F 1 429 ? 229.578 238.876 211.980 1.00 59.99  ? 441 ARG   A NH1    1 
ATOM   7588 N NH2    . ARG   F 1 429 ? 230.441 237.758 213.781 1.00 56.94  ? 441 ARG   A NH2    1 
ATOM   7589 N N      . THR   F 1 430 ? 222.170 239.252 214.590 1.00 52.86  ? 442 THR   A N      1 
ATOM   7590 C CA     . THR   F 1 430 ? 221.045 239.694 213.776 1.00 53.96  ? 442 THR   A CA     1 
ATOM   7591 C C      . THR   F 1 430 ? 220.215 240.744 214.502 1.00 55.84  ? 442 THR   A C      1 
ATOM   7592 O O      . THR   F 1 430 ? 219.707 241.677 213.870 1.00 54.73  ? 442 THR   A O      1 
ATOM   7593 C CB     . THR   F 1 430 ? 220.171 238.505 213.383 1.00 61.96  ? 442 THR   A CB     1 
ATOM   7594 O OG1    . THR   F 1 430 ? 220.101 237.580 214.473 1.00 65.55  ? 442 THR   A OG1    1 
ATOM   7595 C CG2    . THR   F 1 430 ? 220.753 237.801 212.170 1.00 60.85  ? 442 THR   A CG2    1 
ATOM   7596 N N      . GLU   F 1 431 ? 220.071 240.612 215.822 1.00 55.18  ? 443 GLU   A N      1 
ATOM   7597 C CA     . GLU   F 1 431 ? 219.365 241.631 216.591 1.00 55.86  ? 443 GLU   A CA     1 
ATOM   7598 C C      . GLU   F 1 431 ? 220.120 242.952 216.572 1.00 56.47  ? 443 GLU   A C      1 
ATOM   7599 O O      . GLU   F 1 431 ? 219.508 244.026 216.537 1.00 56.98  ? 443 GLU   A O      1 
ATOM   7600 C CB     . GLU   F 1 431 ? 219.152 241.151 218.026 1.00 54.34  ? 443 GLU   A CB     1 
ATOM   7601 C CG     . GLU   F 1 431 ? 218.748 242.249 218.991 1.00 56.77  ? 443 GLU   A CG     1 
ATOM   7602 C CD     . GLU   F 1 431 ? 217.273 242.577 218.916 1.00 63.14  ? 443 GLU   A CD     1 
ATOM   7603 O OE1    . GLU   F 1 431 ? 216.660 242.332 217.857 1.00 68.56  ? 443 GLU   A OE1    1 
ATOM   7604 O OE2    . GLU   F 1 431 ? 216.725 243.083 219.915 1.00 60.28  ? 443 GLU   A OE2    1 
ATOM   7605 N N      . ILE   F 1 432 ? 221.452 242.894 216.597 1.00 56.12  ? 444 ILE   A N      1 
ATOM   7606 C CA     . ILE   F 1 432 ? 222.247 244.115 216.537 1.00 52.79  ? 444 ILE   A CA     1 
ATOM   7607 C C      . ILE   F 1 432 ? 222.025 244.833 215.213 1.00 52.44  ? 444 ILE   A C      1 
ATOM   7608 O O      . ILE   F 1 432 ? 221.856 246.057 215.177 1.00 55.45  ? 444 ILE   A O      1 
ATOM   7609 C CB     . ILE   F 1 432 ? 223.734 243.793 216.766 1.00 51.42  ? 444 ILE   A CB     1 
ATOM   7610 C CG1    . ILE   F 1 432 ? 224.031 243.684 218.261 1.00 49.48  ? 444 ILE   A CG1    1 
ATOM   7611 C CG2    . ILE   F 1 432 ? 224.612 244.854 216.131 1.00 51.48  ? 444 ILE   A CG2    1 
ATOM   7612 C CD1    . ILE   F 1 432 ? 225.502 243.665 218.585 1.00 46.61  ? 444 ILE   A CD1    1 
ATOM   7613 N N      . ILE   F 1 433 ? 222.022 244.088 214.106 1.00 50.90  ? 445 ILE   A N      1 
ATOM   7614 C CA     . ILE   F 1 433 ? 221.799 244.704 212.801 1.00 52.23  ? 445 ILE   A CA     1 
ATOM   7615 C C      . ILE   F 1 433 ? 220.382 245.252 212.706 1.00 51.39  ? 445 ILE   A C      1 
ATOM   7616 O O      . ILE   F 1 433 ? 220.138 246.274 212.056 1.00 52.67  ? 445 ILE   A O      1 
ATOM   7617 C CB     . ILE   F 1 433 ? 222.100 243.700 211.674 1.00 53.21  ? 445 ILE   A CB     1 
ATOM   7618 C CG1    . ILE   F 1 433 ? 223.400 242.953 211.963 1.00 51.44  ? 445 ILE   A CG1    1 
ATOM   7619 C CG2    . ILE   F 1 433 ? 222.197 244.413 210.339 1.00 57.77  ? 445 ILE   A CG2    1 
ATOM   7620 C CD1    . ILE   F 1 433 ? 224.005 242.305 210.746 1.00 50.07  ? 445 ILE   A CD1    1 
ATOM   7621 N N      . ARG   F 1 434 ? 219.424 244.574 213.339 1.00 53.35  ? 446 ARG   A N      1 
ATOM   7622 C CA     . ARG   F 1 434 ? 218.058 245.082 213.367 1.00 54.29  ? 446 ARG   A CA     1 
ATOM   7623 C C      . ARG   F 1 434 ? 217.967 246.407 214.111 1.00 54.82  ? 446 ARG   A C      1 
ATOM   7624 O O      . ARG   F 1 434 ? 217.234 247.307 213.688 1.00 56.19  ? 446 ARG   A O      1 
ATOM   7625 C CB     . ARG   F 1 434 ? 217.126 244.053 214.008 1.00 55.14  ? 446 ARG   A CB     1 
ATOM   7626 C CG     . ARG   F 1 434 ? 215.659 244.437 213.960 1.00 58.16  ? 446 ARG   A CG     1 
ATOM   7627 C CD     . ARG   F 1 434 ? 214.803 243.485 214.776 1.00 59.33  ? 446 ARG   A CD     1 
ATOM   7628 N NE     . ARG   F 1 434 ? 215.111 243.542 216.199 1.00 57.63  ? 446 ARG   A NE     1 
ATOM   7629 C CZ     . ARG   F 1 434 ? 214.556 244.392 217.052 1.00 58.79  ? 446 ARG   A CZ     1 
ATOM   7630 N NH1    . ARG   F 1 434 ? 213.658 245.279 216.657 1.00 61.75  ? 446 ARG   A NH1    1 
ATOM   7631 N NH2    . ARG   F 1 434 ? 214.909 244.349 218.332 1.00 58.21  ? 446 ARG   A NH2    1 
ATOM   7632 N N      . LEU   F 1 435 ? 218.695 246.543 215.220 1.00 54.57  ? 447 LEU   A N      1 
ATOM   7633 C CA     . LEU   F 1 435 ? 218.610 247.761 216.019 1.00 53.24  ? 447 LEU   A CA     1 
ATOM   7634 C C      . LEU   F 1 435 ? 219.112 248.973 215.246 1.00 53.13  ? 447 LEU   A C      1 
ATOM   7635 O O      . LEU   F 1 435 ? 218.505 250.048 215.305 1.00 56.37  ? 447 LEU   A O      1 
ATOM   7636 C CB     . LEU   F 1 435 ? 219.401 247.591 217.314 1.00 54.82  ? 447 LEU   A CB     1 
ATOM   7637 C CG     . LEU   F 1 435 ? 218.749 246.744 218.404 1.00 56.29  ? 447 LEU   A CG     1 
ATOM   7638 C CD1    . LEU   F 1 435 ? 219.797 246.245 219.377 1.00 59.38  ? 447 LEU   A CD1    1 
ATOM   7639 C CD2    . LEU   F 1 435 ? 217.688 247.543 219.130 1.00 50.86  ? 447 LEU   A CD2    1 
ATOM   7640 N N      . MET   F 1 436 ? 220.220 248.823 214.521 1.00 50.69  ? 448 MET   A N      1 
ATOM   7641 C CA     . MET   F 1 436 ? 220.785 249.965 213.813 1.00 54.31  ? 448 MET   A CA     1 
ATOM   7642 C C      . MET   F 1 436 ? 220.032 250.268 212.522 1.00 52.57  ? 448 MET   A C      1 
ATOM   7643 O O      . MET   F 1 436 ? 220.134 251.382 211.999 1.00 54.90  ? 448 MET   A O      1 
ATOM   7644 C CB     . MET   F 1 436 ? 222.272 249.730 213.554 1.00 56.09  ? 448 MET   A CB     1 
ATOM   7645 C CG     . MET   F 1 436 ? 222.652 248.284 213.337 1.00 54.06  ? 448 MET   A CG     1 
ATOM   7646 S SD     . MET   F 1 436 ? 224.338 247.970 213.884 1.00 54.27  ? 448 MET   A SD     1 
ATOM   7647 C CE     . MET   F 1 436 ? 225.269 248.698 212.545 1.00 44.35  ? 448 MET   A CE     1 
ATOM   7648 N N      . GLU   F 1 437 ? 219.278 249.302 211.991 1.00 52.03  ? 449 GLU   A N      1 
ATOM   7649 C CA     . GLU   F 1 437 ? 218.376 249.616 210.887 1.00 55.75  ? 449 GLU   A CA     1 
ATOM   7650 C C      . GLU   F 1 437 ? 217.234 250.518 211.332 1.00 56.85  ? 449 GLU   A C      1 
ATOM   7651 O O      . GLU   F 1 437 ? 216.853 251.441 210.603 1.00 58.80  ? 449 GLU   A O      1 
ATOM   7652 C CB     . GLU   F 1 437 ? 217.826 248.336 210.263 1.00 57.93  ? 449 GLU   A CB     1 
ATOM   7653 C CG     . GLU   F 1 437 ? 218.891 247.406 209.741 1.00 68.76  ? 449 GLU   A CG     1 
ATOM   7654 C CD     . GLU   F 1 437 ? 218.744 247.153 208.260 1.00 87.81  ? 449 GLU   A CD     1 
ATOM   7655 O OE1    . GLU   F 1 437 ? 219.504 246.325 207.716 1.00 98.36  ? 449 GLU   A OE1    1 
ATOM   7656 O OE2    . GLU   F 1 437 ? 217.860 247.781 207.639 1.00 86.24  ? 449 GLU   A OE2    1 
ATOM   7657 N N      . SER   F 1 438 ? 216.672 250.271 212.515 1.00 52.56  ? 450 SER   A N      1 
ATOM   7658 C CA     . SER   F 1 438 ? 215.649 251.170 213.034 1.00 53.32  ? 450 SER   A CA     1 
ATOM   7659 C C      . SER   F 1 438 ? 216.235 252.540 213.343 1.00 59.01  ? 450 SER   A C      1 
ATOM   7660 O O      . SER   F 1 438 ? 215.527 253.552 213.294 1.00 67.38  ? 450 SER   A O      1 
ATOM   7661 C CB     . SER   F 1 438 ? 215.000 250.572 214.280 1.00 58.77  ? 450 SER   A CB     1 
ATOM   7662 O OG     . SER   F 1 438 ? 215.745 250.890 215.441 1.00 63.25  ? 450 SER   A OG     1 
ATOM   7663 N N      . ALA   F 1 439 ? 217.524 252.592 213.667 1.00 53.20  ? 451 ALA   A N      1 
ATOM   7664 C CA     . ALA   F 1 439 ? 218.165 253.857 213.987 1.00 53.33  ? 451 ALA   A CA     1 
ATOM   7665 C C      . ALA   F 1 439 ? 218.264 254.742 212.751 1.00 53.85  ? 451 ALA   A C      1 
ATOM   7666 O O      . ALA   F 1 439 ? 218.647 254.292 211.669 1.00 50.75  ? 451 ALA   A O      1 
ATOM   7667 C CB     . ALA   F 1 439 ? 219.555 253.614 214.569 1.00 51.55  ? 451 ALA   A CB     1 
ATOM   7668 N N      . ARG   F 1 440 ? 217.930 256.014 212.928 1.00 56.07  ? 452 ARG   A N      1 
ATOM   7669 C CA     . ARG   F 1 440 ? 217.995 257.022 211.885 1.00 55.49  ? 452 ARG   A CA     1 
ATOM   7670 C C      . ARG   F 1 440 ? 218.892 258.158 212.346 1.00 57.41  ? 452 ARG   A C      1 
ATOM   7671 O O      . ARG   F 1 440 ? 218.972 258.440 213.545 1.00 59.56  ? 452 ARG   A O      1 
ATOM   7672 C CB     . ARG   F 1 440 ? 216.601 257.578 211.559 1.00 58.61  ? 452 ARG   A CB     1 
ATOM   7673 C CG     . ARG   F 1 440 ? 215.608 256.561 211.022 1.00 57.13  ? 452 ARG   A CG     1 
ATOM   7674 C CD     . ARG   F 1 440 ? 216.258 255.583 210.067 1.00 52.12  ? 452 ARG   A CD     1 
ATOM   7675 N NE     . ARG   F 1 440 ? 215.288 254.637 209.530 1.00 52.54  ? 452 ARG   A NE     1 
ATOM   7676 C CZ     . ARG   F 1 440 ? 215.538 253.793 208.539 1.00 57.21  ? 452 ARG   A CZ     1 
ATOM   7677 N NH1    . ARG   F 1 440 ? 216.712 253.767 207.935 1.00 54.11  ? 452 ARG   A NH1    1 
ATOM   7678 N NH2    . ARG   F 1 440 ? 214.583 252.960 208.139 1.00 62.68  ? 452 ARG   A NH2    1 
ATOM   7679 N N      . PRO   F 1 441 ? 219.582 258.826 211.421 1.00 58.74  ? 453 PRO   A N      1 
ATOM   7680 C CA     . PRO   F 1 441 ? 220.389 260.001 211.778 1.00 59.81  ? 453 PRO   A CA     1 
ATOM   7681 C C      . PRO   F 1 441 ? 219.548 261.264 211.935 1.00 59.11  ? 453 PRO   A C      1 
ATOM   7682 O O      . PRO   F 1 441 ? 219.916 262.341 211.465 1.00 64.50  ? 453 PRO   A O      1 
ATOM   7683 C CB     . PRO   F 1 441 ? 221.372 260.112 210.608 1.00 62.58  ? 453 PRO   A CB     1 
ATOM   7684 C CG     . PRO   F 1 441 ? 220.983 259.075 209.600 1.00 61.13  ? 453 PRO   A CG     1 
ATOM   7685 C CD     . PRO   F 1 441 ? 219.685 258.479 209.998 1.00 60.93  ? 453 PRO   A CD     1 
ATOM   7686 N N      . GLU   F 1 442 ? 218.412 261.130 212.614 1.00 56.39  ? 454 GLU   A N      1 
ATOM   7687 C CA     . GLU   F 1 442 ? 217.577 262.269 212.968 1.00 55.90  ? 454 GLU   A CA     1 
ATOM   7688 C C      . GLU   F 1 442 ? 216.971 262.155 214.353 1.00 55.87  ? 454 GLU   A C      1 
ATOM   7689 O O      . GLU   F 1 442 ? 216.375 263.130 214.820 1.00 55.66  ? 454 GLU   A O      1 
ATOM   7690 C CB     . GLU   F 1 442 ? 216.447 262.462 211.948 1.00 53.23  ? 454 GLU   A CB     1 
ATOM   7691 C CG     . GLU   F 1 442 ? 216.908 262.963 210.598 1.00 56.34  ? 454 GLU   A CG     1 
ATOM   7692 C CD     . GLU   F 1 442 ? 217.072 261.844 209.594 1.00 73.99  ? 454 GLU   A CD     1 
ATOM   7693 O OE1    . GLU   F 1 442 ? 217.199 262.139 208.387 1.00 86.92  ? 454 GLU   A OE1    1 
ATOM   7694 O OE2    . GLU   F 1 442 ? 217.071 260.668 210.012 1.00 74.46  ? 454 GLU   A OE2    1 
ATOM   7695 N N      . ASP   F 1 443 ? 217.083 261.010 215.020 1.00 55.56  ? 455 ASP   A N      1 
ATOM   7696 C CA     . ASP   F 1 443 ? 216.582 260.892 216.379 1.00 57.80  ? 455 ASP   A CA     1 
ATOM   7697 C C      . ASP   F 1 443 ? 217.246 261.936 217.262 1.00 55.60  ? 455 ASP   A C      1 
ATOM   7698 O O      . ASP   F 1 443 ? 218.468 262.107 217.231 1.00 60.57  ? 455 ASP   A O      1 
ATOM   7699 C CB     . ASP   F 1 443 ? 216.849 259.490 216.923 1.00 62.30  ? 455 ASP   A CB     1 
ATOM   7700 C CG     . ASP   F 1 443 ? 216.549 258.407 215.912 1.00 65.98  ? 455 ASP   A CG     1 
ATOM   7701 O OD1    . ASP   F 1 443 ? 217.051 257.278 216.083 1.00 64.04  ? 455 ASP   A OD1    1 
ATOM   7702 O OD2    . ASP   F 1 443 ? 215.815 258.686 214.942 1.00 70.41  ? 455 ASP   A OD2    1 
ATOM   7703 N N      . VAL   F 1 444 ? 216.442 262.636 218.045 1.00 51.67  ? 456 VAL   A N      1 
ATOM   7704 C CA     . VAL   F 1 444 ? 216.944 263.668 218.939 1.00 51.52  ? 456 VAL   A CA     1 
ATOM   7705 C C      . VAL   F 1 444 ? 217.454 263.004 220.207 1.00 54.02  ? 456 VAL   A C      1 
ATOM   7706 O O      . VAL   F 1 444 ? 216.763 262.174 220.809 1.00 57.31  ? 456 VAL   A O      1 
ATOM   7707 C CB     . VAL   F 1 444 ? 215.853 264.702 219.254 1.00 52.52  ? 456 VAL   A CB     1 
ATOM   7708 C CG1    . VAL   F 1 444 ? 216.224 265.499 220.489 1.00 53.63  ? 456 VAL   A CG1    1 
ATOM   7709 C CG2    . VAL   F 1 444 ? 215.644 265.621 218.066 1.00 52.58  ? 456 VAL   A CG2    1 
ATOM   7710 N N      . SER   F 1 445 ? 218.670 263.356 220.604 1.00 52.16  ? 457 SER   A N      1 
ATOM   7711 C CA     . SER   F 1 445 ? 219.272 262.869 221.832 1.00 48.51  ? 457 SER   A CA     1 
ATOM   7712 C C      . SER   F 1 445 ? 219.388 264.008 222.835 1.00 51.96  ? 457 SER   A C      1 
ATOM   7713 O O      . SER   F 1 445 ? 219.333 265.188 222.477 1.00 56.38  ? 457 SER   A O      1 
ATOM   7714 C CB     . SER   F 1 445 ? 220.649 262.259 221.559 1.00 51.76  ? 457 SER   A CB     1 
ATOM   7715 O OG     . SER   F 1 445 ? 220.548 260.866 221.329 1.00 58.90  ? 457 SER   A OG     1 
ATOM   7716 N N      . PHE   F 1 446 ? 219.550 263.642 224.104 1.00 50.76  ? 458 PHE   A N      1 
ATOM   7717 C CA     . PHE   F 1 446 ? 219.683 264.616 225.185 1.00 53.78  ? 458 PHE   A CA     1 
ATOM   7718 C C      . PHE   F 1 446 ? 218.510 265.593 225.185 1.00 53.73  ? 458 PHE   A C      1 
ATOM   7719 O O      . PHE   F 1 446 ? 218.683 266.812 225.229 1.00 58.79  ? 458 PHE   A O      1 
ATOM   7720 C CB     . PHE   F 1 446 ? 221.011 265.366 225.085 1.00 56.13  ? 458 PHE   A CB     1 
ATOM   7721 C CG     . PHE   F 1 446 ? 222.212 264.474 224.984 1.00 49.52  ? 458 PHE   A CG     1 
ATOM   7722 C CD1    . PHE   F 1 446 ? 222.698 263.816 226.097 1.00 51.92  ? 458 PHE   A CD1    1 
ATOM   7723 C CD2    . PHE   F 1 446 ? 222.863 264.303 223.776 1.00 46.65  ? 458 PHE   A CD2    1 
ATOM   7724 C CE1    . PHE   F 1 446 ? 223.805 263.000 226.006 1.00 52.40  ? 458 PHE   A CE1    1 
ATOM   7725 C CE2    . PHE   F 1 446 ? 223.970 263.487 223.680 1.00 49.74  ? 458 PHE   A CE2    1 
ATOM   7726 C CZ     . PHE   F 1 446 ? 224.442 262.836 224.796 1.00 53.93  ? 458 PHE   A CZ     1 
ATOM   7727 N N      . GLN   F 1 447 ? 217.300 265.044 225.130 1.00 52.81  ? 459 GLN   A N      1 
ATOM   7728 C CA     . GLN   F 1 447 ? 216.110 265.879 225.045 1.00 57.45  ? 459 GLN   A CA     1 
ATOM   7729 C C      . GLN   F 1 447 ? 216.034 266.843 226.222 1.00 56.86  ? 459 GLN   A C      1 
ATOM   7730 O O      . GLN   F 1 447 ? 216.149 266.440 227.382 1.00 57.99  ? 459 GLN   A O      1 
ATOM   7731 C CB     . GLN   F 1 447 ? 214.858 265.008 224.997 1.00 54.78  ? 459 GLN   A CB     1 
ATOM   7732 C CG     . GLN   F 1 447 ? 214.344 264.759 223.596 1.00 57.67  ? 459 GLN   A CG     1 
ATOM   7733 C CD     . GLN   F 1 447 ? 213.327 265.792 223.170 1.00 66.74  ? 459 GLN   A CD     1 
ATOM   7734 O OE1    . GLN   F 1 447 ? 213.002 266.705 223.927 1.00 66.36  ? 459 GLN   A OE1    1 
ATOM   7735 N NE2    . GLN   F 1 447 ? 212.819 265.656 221.952 1.00 74.00  ? 459 GLN   A NE2    1 
ATOM   7736 N N      . GLY   F 1 448 ? 215.836 268.122 225.915 1.00 52.00  ? 460 GLY   A N      1 
ATOM   7737 C CA     . GLY   F 1 448 ? 215.694 269.140 226.930 1.00 51.46  ? 460 GLY   A CA     1 
ATOM   7738 C C      . GLY   F 1 448 ? 216.986 269.612 227.553 1.00 54.60  ? 460 GLY   A C      1 
ATOM   7739 O O      . GLY   F 1 448 ? 216.949 270.496 228.417 1.00 59.43  ? 460 GLY   A O      1 
ATOM   7740 N N      . ARG   F 1 449 ? 218.123 269.062 227.143 1.00 55.42  ? 461 ARG   A N      1 
ATOM   7741 C CA     . ARG   F 1 449 ? 219.422 269.415 227.698 1.00 55.78  ? 461 ARG   A CA     1 
ATOM   7742 C C      . ARG   F 1 449 ? 220.138 270.320 226.708 1.00 53.82  ? 461 ARG   A C      1 
ATOM   7743 O O      . ARG   F 1 449 ? 220.292 269.963 225.536 1.00 57.44  ? 461 ARG   A O      1 
ATOM   7744 C CB     . ARG   F 1 449 ? 220.244 268.162 227.996 1.00 54.03  ? 461 ARG   A CB     1 
ATOM   7745 C CG     . ARG   F 1 449 ? 220.227 267.755 229.458 1.00 56.53  ? 461 ARG   A CG     1 
ATOM   7746 C CD     . ARG   F 1 449 ? 218.876 267.194 229.862 1.00 59.83  ? 461 ARG   A CD     1 
ATOM   7747 N NE     . ARG   F 1 449 ? 218.974 266.290 231.000 1.00 66.53  ? 461 ARG   A NE     1 
ATOM   7748 C CZ     . ARG   F 1 449 ? 219.676 265.166 231.007 1.00 80.52  ? 461 ARG   A CZ     1 
ATOM   7749 N NH1    . ARG   F 1 449 ? 220.352 264.767 229.943 1.00 79.68  ? 461 ARG   A NH1    1 
ATOM   7750 N NH2    . ARG   F 1 449 ? 219.699 264.422 232.109 1.00 87.26  ? 461 ARG   A NH2    1 
ATOM   7751 N N      . GLY   F 1 450 ? 220.568 271.485 227.178 1.00 52.11  ? 462 GLY   A N      1 
ATOM   7752 C CA     . GLY   F 1 450 ? 221.143 272.472 226.291 1.00 55.02  ? 462 GLY   A CA     1 
ATOM   7753 C C      . GLY   F 1 450 ? 222.470 273.042 226.744 1.00 57.30  ? 462 GLY   A C      1 
ATOM   7754 O O      . GLY   F 1 450 ? 223.286 272.348 227.355 1.00 58.24  ? 462 GLY   A O      1 
ATOM   7755 N N      . VAL   F 1 451 ? 222.686 274.318 226.440 1.00 54.99  ? 463 VAL   A N      1 
ATOM   7756 C CA     . VAL   F 1 451 ? 223.949 275.002 226.681 1.00 49.53  ? 463 VAL   A CA     1 
ATOM   7757 C C      . VAL   F 1 451 ? 223.664 276.255 227.494 1.00 51.44  ? 463 VAL   A C      1 
ATOM   7758 O O      . VAL   F 1 451 ? 222.682 276.958 227.233 1.00 54.01  ? 463 VAL   A O      1 
ATOM   7759 C CB     . VAL   F 1 451 ? 224.658 275.359 225.362 1.00 48.65  ? 463 VAL   A CB     1 
ATOM   7760 C CG1    . VAL   F 1 451 ? 225.896 276.170 225.641 1.00 52.39  ? 463 VAL   A CG1    1 
ATOM   7761 C CG2    . VAL   F 1 451 ? 225.003 274.100 224.591 1.00 53.09  ? 463 VAL   A CG2    1 
ATOM   7762 N N      . PHE   F 1 452 ? 224.511 276.527 228.479 1.00 51.91  ? 464 PHE   A N      1 
ATOM   7763 C CA     . PHE   F 1 452 ? 224.297 277.623 229.407 1.00 50.65  ? 464 PHE   A CA     1 
ATOM   7764 C C      . PHE   F 1 452 ? 225.258 278.772 229.114 1.00 51.48  ? 464 PHE   A C      1 
ATOM   7765 O O      . PHE   F 1 452 ? 226.130 278.690 228.246 1.00 52.36  ? 464 PHE   A O      1 
ATOM   7766 C CB     . PHE   F 1 452 ? 224.453 277.134 230.847 1.00 49.47  ? 464 PHE   A CB     1 
ATOM   7767 C CG     . PHE   F 1 452 ? 224.039 275.710 231.047 1.00 51.38  ? 464 PHE   A CG     1 
ATOM   7768 C CD1    . PHE   F 1 452 ? 224.930 274.677 230.819 1.00 54.86  ? 464 PHE   A CD1    1 
ATOM   7769 C CD2    . PHE   F 1 452 ? 222.762 275.402 231.471 1.00 49.86  ? 464 PHE   A CD2    1 
ATOM   7770 C CE1    . PHE   F 1 452 ? 224.550 273.368 231.000 1.00 55.45  ? 464 PHE   A CE1    1 
ATOM   7771 C CE2    . PHE   F 1 452 ? 222.380 274.094 231.656 1.00 50.55  ? 464 PHE   A CE2    1 
ATOM   7772 C CZ     . PHE   F 1 452 ? 223.276 273.077 231.420 1.00 53.79  ? 464 PHE   A CZ     1 
ATOM   7773 N N      . GLU   F 1 453 ? 225.096 279.855 229.863 1.00 48.86  ? 465 GLU   A N      1 
ATOM   7774 C CA     . GLU   F 1 453 ? 225.930 281.039 229.743 1.00 47.97  ? 465 GLU   A CA     1 
ATOM   7775 C C      . GLU   F 1 453 ? 227.057 280.984 230.765 1.00 53.16  ? 465 GLU   A C      1 
ATOM   7776 O O      . GLU   F 1 453 ? 226.939 280.356 231.820 1.00 58.42  ? 465 GLU   A O      1 
ATOM   7777 C CB     . GLU   F 1 453 ? 225.106 282.314 229.949 1.00 48.17  ? 465 GLU   A CB     1 
ATOM   7778 C CG     . GLU   F 1 453 ? 224.108 282.603 228.849 1.00 49.97  ? 465 GLU   A CG     1 
ATOM   7779 C CD     . GLU   F 1 453 ? 224.463 283.842 228.056 1.00 59.98  ? 465 GLU   A CD     1 
ATOM   7780 O OE1    . GLU   F 1 453 ? 225.647 284.234 228.068 1.00 65.20  ? 465 GLU   A OE1    1 
ATOM   7781 O OE2    . GLU   F 1 453 ? 223.559 284.427 227.428 1.00 66.12  ? 465 GLU   A OE2    1 
ATOM   7782 N N      . LEU   F 1 454 ? 228.163 281.654 230.437 1.00 52.18  ? 466 LEU   A N      1 
ATOM   7783 C CA     . LEU   F 1 454 ? 229.287 281.696 231.366 1.00 50.42  ? 466 LEU   A CA     1 
ATOM   7784 C C      . LEU   F 1 454 ? 228.892 282.340 232.686 1.00 53.06  ? 466 LEU   A C      1 
ATOM   7785 O O      . LEU   F 1 454 ? 229.465 282.016 233.732 1.00 56.78  ? 466 LEU   A O      1 
ATOM   7786 C CB     . LEU   F 1 454 ? 230.464 282.442 230.738 1.00 48.96  ? 466 LEU   A CB     1 
ATOM   7787 C CG     . LEU   F 1 454 ? 231.480 281.593 229.974 1.00 47.73  ? 466 LEU   A CG     1 
ATOM   7788 C CD1    . LEU   F 1 454 ? 232.421 280.898 230.936 1.00 46.60  ? 466 LEU   A CD1    1 
ATOM   7789 C CD2    . LEU   F 1 454 ? 230.776 280.581 229.094 1.00 50.13  ? 466 LEU   A CD2    1 
ATOM   7790 N N      . SER   F 1 455 ? 227.916 283.246 232.662 1.00 50.96  ? 467 SER   A N      1 
ATOM   7791 C CA     . SER   F 1 455 ? 227.434 283.894 233.873 1.00 51.95  ? 467 SER   A CA     1 
ATOM   7792 C C      . SER   F 1 455 ? 226.500 283.008 234.686 1.00 50.21  ? 467 SER   A C      1 
ATOM   7793 O O      . SER   F 1 455 ? 226.233 283.320 235.851 1.00 53.69  ? 467 SER   A O      1 
ATOM   7794 C CB     . SER   F 1 455 ? 226.718 285.197 233.516 1.00 53.71  ? 467 SER   A CB     1 
ATOM   7795 O OG     . SER   F 1 455 ? 227.524 286.005 232.678 1.00 52.96  ? 467 SER   A OG     1 
ATOM   7796 N N      . ASP   F 1 456 ? 226.000 281.923 234.104 1.00 51.84  ? 468 ASP   A N      1 
ATOM   7797 C CA     . ASP   F 1 456 ? 225.061 281.024 234.769 1.00 52.96  ? 468 ASP   A CA     1 
ATOM   7798 C C      . ASP   F 1 456 ? 225.879 279.868 235.336 1.00 54.75  ? 468 ASP   A C      1 
ATOM   7799 O O      . ASP   F 1 456 ? 226.000 278.807 234.725 1.00 56.14  ? 468 ASP   A O      1 
ATOM   7800 C CB     . ASP   F 1 456 ? 223.990 280.556 233.791 1.00 52.09  ? 468 ASP   A CB     1 
ATOM   7801 C CG     . ASP   F 1 456 ? 222.905 279.744 234.454 1.00 58.75  ? 468 ASP   A CG     1 
ATOM   7802 O OD1    . ASP   F 1 456 ? 223.185 279.077 235.471 1.00 65.65  ? 468 ASP   A OD1    1 
ATOM   7803 O OD2    . ASP   F 1 456 ? 221.762 279.775 233.956 1.00 58.49  ? 468 ASP   A OD2    1 
ATOM   7804 N N      . GLU   F 1 457 ? 226.444 280.083 236.521 1.00 55.90  ? 469 GLU   A N      1 
ATOM   7805 C CA     . GLU   F 1 457 ? 227.353 279.118 237.122 1.00 55.72  ? 469 GLU   A CA     1 
ATOM   7806 C C      . GLU   F 1 457 ? 226.643 277.897 237.688 1.00 57.16  ? 469 GLU   A C      1 
ATOM   7807 O O      . GLU   F 1 457 ? 227.296 276.873 237.914 1.00 56.20  ? 469 GLU   A O      1 
ATOM   7808 C CB     . GLU   F 1 457 ? 228.167 279.790 238.228 1.00 52.33  ? 469 GLU   A CB     1 
ATOM   7809 C CG     . GLU   F 1 457 ? 229.414 280.494 237.732 1.00 55.08  ? 469 GLU   A CG     1 
ATOM   7810 C CD     . GLU   F 1 457 ? 229.806 281.661 238.609 1.00 69.15  ? 469 GLU   A CD     1 
ATOM   7811 O OE1    . GLU   F 1 457 ? 228.903 282.294 239.193 1.00 70.45  ? 469 GLU   A OE1    1 
ATOM   7812 O OE2    . GLU   F 1 457 ? 231.017 281.946 238.716 1.00 78.78  ? 469 GLU   A OE2    1 
ATOM   7813 N N      . LYS   F 1 458 ? 225.337 277.975 237.922 1.00 57.74  ? 470 LYS   A N      1 
ATOM   7814 C CA     . LYS   F 1 458 ? 224.574 276.855 238.449 1.00 55.01  ? 470 LYS   A CA     1 
ATOM   7815 C C      . LYS   F 1 458 ? 223.885 276.045 237.363 1.00 55.22  ? 470 LYS   A C      1 
ATOM   7816 O O      . LYS   F 1 458 ? 223.218 275.054 237.677 1.00 60.94  ? 470 LYS   A O      1 
ATOM   7817 C CB     . LYS   F 1 458 ? 223.534 277.354 239.457 1.00 54.25  ? 470 LYS   A CB     1 
ATOM   7818 C CG     . LYS   F 1 458 ? 224.101 278.265 240.527 1.00 54.62  ? 470 LYS   A CG     1 
ATOM   7819 C CD     . LYS   F 1 458 ? 224.914 277.486 241.542 1.00 50.58  ? 470 LYS   A CD     1 
ATOM   7820 C CE     . LYS   F 1 458 ? 224.038 276.990 242.675 1.00 51.46  ? 470 LYS   A CE     1 
ATOM   7821 N NZ     . LYS   F 1 458 ? 222.991 277.984 243.029 1.00 51.87  ? 470 LYS   A NZ     1 
ATOM   7822 N N      . ALA   F 1 459 ? 224.033 276.430 236.097 1.00 53.17  ? 471 ALA   A N      1 
ATOM   7823 C CA     . ALA   F 1 459 ? 223.390 275.726 234.990 1.00 56.26  ? 471 ALA   A CA     1 
ATOM   7824 C C      . ALA   F 1 459 ? 221.875 275.677 235.172 1.00 57.93  ? 471 ALA   A C      1 
ATOM   7825 O O      . ALA   F 1 459 ? 221.253 274.619 235.068 1.00 61.06  ? 471 ALA   A O      1 
ATOM   7826 C CB     . ALA   F 1 459 ? 223.962 274.317 234.829 1.00 53.88  ? 471 ALA   A CB     1 
ATOM   7827 N N      . THR   F 1 460 ? 221.274 276.834 235.444 1.00 55.35  ? 472 THR   A N      1 
ATOM   7828 C CA     . THR   F 1 460 ? 219.844 276.889 235.720 1.00 56.27  ? 472 THR   A CA     1 
ATOM   7829 C C      . THR   F 1 460 ? 219.007 276.951 234.445 1.00 57.03  ? 472 THR   A C      1 
ATOM   7830 O O      . THR   F 1 460 ? 218.065 276.171 234.284 1.00 60.02  ? 472 THR   A O      1 
ATOM   7831 C CB     . THR   F 1 460 ? 219.526 278.088 236.618 1.00 57.89  ? 472 THR   A CB     1 
ATOM   7832 O OG1    . THR   F 1 460 ? 220.240 279.238 236.153 1.00 67.74  ? 472 THR   A OG1    1 
ATOM   7833 C CG2    . THR   F 1 460 ? 219.927 277.797 238.052 1.00 54.63  ? 472 THR   A CG2    1 
ATOM   7834 N N      . SER   F 1 461 ? 219.337 277.859 233.529 1.00 56.24  ? 473 SER   A N      1 
ATOM   7835 C CA     . SER   F 1 461 ? 218.529 278.054 232.328 1.00 58.79  ? 473 SER   A CA     1 
ATOM   7836 C C      . SER   F 1 461 ? 219.268 277.541 231.101 1.00 58.31  ? 473 SER   A C      1 
ATOM   7837 O O      . SER   F 1 461 ? 220.174 278.219 230.593 1.00 62.21  ? 473 SER   A O      1 
ATOM   7838 C CB     . SER   F 1 461 ? 218.169 279.533 232.159 1.00 53.99  ? 473 SER   A CB     1 
ATOM   7839 O OG     . SER   F 1 461 ? 219.329 280.323 231.984 1.00 61.30  ? 473 SER   A OG     1 
ATOM   7840 N N      . PRO   F 1 462 ? 218.928 276.361 230.588 1.00 58.02  ? 474 PRO   A N      1 
ATOM   7841 C CA     . PRO   F 1 462 ? 219.593 275.865 229.380 1.00 57.01  ? 474 PRO   A CA     1 
ATOM   7842 C C      . PRO   F 1 462 ? 219.189 276.658 228.150 1.00 56.56  ? 474 PRO   A C      1 
ATOM   7843 O O      . PRO   F 1 462 ? 218.084 277.198 228.060 1.00 59.65  ? 474 PRO   A O      1 
ATOM   7844 C CB     . PRO   F 1 462 ? 219.119 274.408 229.279 1.00 53.33  ? 474 PRO   A CB     1 
ATOM   7845 C CG     . PRO   F 1 462 ? 218.457 274.100 230.585 1.00 55.45  ? 474 PRO   A CG     1 
ATOM   7846 C CD     . PRO   F 1 462 ? 217.949 275.399 231.112 1.00 58.56  ? 474 PRO   A CD     1 
ATOM   7847 N N      . ILE   F 1 463 ? 220.103 276.714 227.188 1.00 52.87  ? 475 ILE   A N      1 
ATOM   7848 C CA     . ILE   F 1 463 ? 219.866 277.358 225.901 1.00 51.43  ? 475 ILE   A CA     1 
ATOM   7849 C C      . ILE   F 1 463 ? 219.941 276.261 224.848 1.00 51.18  ? 475 ILE   A C      1 
ATOM   7850 O O      . ILE   F 1 463 ? 221.033 275.856 224.433 1.00 53.73  ? 475 ILE   A O      1 
ATOM   7851 C CB     . ILE   F 1 463 ? 220.866 278.484 225.616 1.00 53.27  ? 475 ILE   A CB     1 
ATOM   7852 C CG1    . ILE   F 1 463 ? 220.661 279.640 226.594 1.00 48.23  ? 475 ILE   A CG1    1 
ATOM   7853 C CG2    . ILE   F 1 463 ? 220.723 278.971 224.187 1.00 53.86  ? 475 ILE   A CG2    1 
ATOM   7854 C CD1    . ILE   F 1 463 ? 221.687 279.696 227.695 1.00 54.98  ? 475 ILE   A CD1    1 
ATOM   7855 N N      . VAL   F 1 464 ? 218.783 275.773 224.417 1.00 49.09  ? 476 VAL   A N      1 
ATOM   7856 C CA     . VAL   F 1 464 ? 218.700 274.698 223.432 1.00 48.96  ? 476 VAL   A CA     1 
ATOM   7857 C C      . VAL   F 1 464 ? 219.034 275.246 222.050 1.00 49.12  ? 476 VAL   A C      1 
ATOM   7858 O O      . VAL   F 1 464 ? 218.426 276.231 221.609 1.00 45.18  ? 476 VAL   A O      1 
ATOM   7859 C CB     . VAL   F 1 464 ? 217.310 274.045 223.443 1.00 49.22  ? 476 VAL   A CB     1 
ATOM   7860 C CG1    . VAL   F 1 464 ? 217.245 272.933 222.417 1.00 53.11  ? 476 VAL   A CG1    1 
ATOM   7861 C CG2    . VAL   F 1 464 ? 216.989 273.517 224.826 1.00 52.32  ? 476 VAL   A CG2    1 
ATOM   7862 N N      . PRO   F 1 465 ? 219.983 274.651 221.336 1.00 54.35  ? 477 PRO   A N      1 
ATOM   7863 C CA     . PRO   F 1 465 ? 220.325 275.144 220.002 1.00 54.52  ? 477 PRO   A CA     1 
ATOM   7864 C C      . PRO   F 1 465 ? 219.366 274.624 218.942 1.00 56.91  ? 477 PRO   A C      1 
ATOM   7865 O O      . PRO   F 1 465 ? 218.763 273.558 219.070 1.00 60.79  ? 477 PRO   A O      1 
ATOM   7866 C CB     . PRO   F 1 465 ? 221.736 274.589 219.783 1.00 53.76  ? 477 PRO   A CB     1 
ATOM   7867 C CG     . PRO   F 1 465 ? 221.725 273.302 220.530 1.00 47.93  ? 477 PRO   A CG     1 
ATOM   7868 C CD     . PRO   F 1 465 ? 220.832 273.514 221.735 1.00 56.28  ? 477 PRO   A CD     1 
ATOM   7869 N N      . SER   F 1 466 ? 219.235 275.411 217.880 1.00 51.49  ? 478 SER   A N      1 
ATOM   7870 C CA     . SER   F 1 466 ? 218.493 275.017 216.692 1.00 49.53  ? 478 SER   A CA     1 
ATOM   7871 C C      . SER   F 1 466 ? 219.432 275.079 215.499 1.00 53.47  ? 478 SER   A C      1 
ATOM   7872 O O      . SER   F 1 466 ? 220.075 276.107 215.263 1.00 58.53  ? 478 SER   A O      1 
ATOM   7873 C CB     . SER   F 1 466 ? 217.277 275.918 216.464 1.00 48.55  ? 478 SER   A CB     1 
ATOM   7874 O OG     . SER   F 1 466 ? 217.667 277.271 216.315 1.00 60.66  ? 478 SER   A OG     1 
ATOM   7875 N N      . PHE   F 1 467 ? 219.512 273.986 214.754 1.00 50.88  ? 479 PHE   A N      1 
ATOM   7876 C CA     . PHE   F 1 467 ? 220.428 273.905 213.627 1.00 49.80  ? 479 PHE   A CA     1 
ATOM   7877 C C      . PHE   F 1 467 ? 219.681 273.987 212.301 1.00 42.89  ? 479 PHE   A C      1 
ATOM   7878 O O      . PHE   F 1 467 ? 220.066 273.356 211.319 1.00 45.30  ? 479 PHE   A O      1 
ATOM   7879 C CB     . PHE   F 1 467 ? 221.242 272.613 213.705 1.00 48.88  ? 479 PHE   A CB     1 
ATOM   7880 C CG     . PHE   F 1 467 ? 222.136 272.535 214.909 1.00 51.50  ? 479 PHE   A CG     1 
ATOM   7881 C CD1    . PHE   F 1 467 ? 222.875 273.633 215.312 1.00 50.90  ? 479 PHE   A CD1    1 
ATOM   7882 C CD2    . PHE   F 1 467 ? 222.235 271.366 215.641 1.00 50.08  ? 479 PHE   A CD2    1 
ATOM   7883 C CE1    . PHE   F 1 467 ? 223.697 273.565 216.417 1.00 47.66  ? 479 PHE   A CE1    1 
ATOM   7884 C CE2    . PHE   F 1 467 ? 223.055 271.294 216.746 1.00 50.69  ? 479 PHE   A CE2    1 
ATOM   7885 C CZ     . PHE   F 1 467 ? 223.787 272.395 217.134 1.00 49.77  ? 479 PHE   A CZ     1 
ATOM   7886 N N      . GLU   F 1 472 ? 227.731 273.408 206.201 1.00 74.75  ? 484 GLU   A N      1 
ATOM   7887 C CA     . GLU   F 1 472 ? 226.749 272.751 207.103 1.00 78.09  ? 484 GLU   A CA     1 
ATOM   7888 C C      . GLU   F 1 472 ? 227.298 271.386 207.545 1.00 78.23  ? 484 GLU   A C      1 
ATOM   7889 O O      . GLU   F 1 472 ? 226.516 270.592 208.112 1.00 73.23  ? 484 GLU   A O      1 
ATOM   7890 C CB     . GLU   F 1 472 ? 225.401 272.590 206.400 1.00 76.97  ? 484 GLU   A CB     1 
ATOM   7891 C CG     . GLU   F 1 472 ? 224.708 273.919 206.113 1.00 80.96  ? 484 GLU   A CG     1 
ATOM   7892 C CD     . GLU   F 1 472 ? 223.403 273.783 205.351 1.00 77.18  ? 484 GLU   A CD     1 
ATOM   7893 O OE1    . GLU   F 1 472 ? 223.114 272.668 204.869 1.00 62.34  ? 484 GLU   A OE1    1 
ATOM   7894 O OE2    . GLU   F 1 472 ? 222.671 274.790 205.249 1.00 75.86  ? 484 GLU   A OE2    1 
ATOM   7895 N N      . GLY   F 1 473 ? 228.585 271.127 207.293 1.00 77.60  ? 485 GLY   A N      1 
ATOM   7896 C CA     . GLY   F 1 473 ? 229.175 269.862 207.670 1.00 63.04  ? 485 GLY   A CA     1 
ATOM   7897 C C      . GLY   F 1 473 ? 229.212 269.668 209.172 1.00 62.64  ? 485 GLY   A C      1 
ATOM   7898 O O      . GLY   F 1 473 ? 229.060 270.604 209.957 1.00 66.95  ? 485 GLY   A O      1 
ATOM   7899 N N      . SER   F 1 474 ? 229.416 268.415 209.576 1.00 55.69  ? 486 SER   A N      1 
ATOM   7900 C CA     . SER   F 1 474 ? 229.456 268.079 210.990 1.00 54.14  ? 486 SER   A CA     1 
ATOM   7901 C C      . SER   F 1 474 ? 230.576 267.119 211.365 1.00 55.06  ? 486 SER   A C      1 
ATOM   7902 O O      . SER   F 1 474 ? 230.631 266.694 212.522 1.00 55.70  ? 486 SER   A O      1 
ATOM   7903 C CB     . SER   F 1 474 ? 228.111 267.480 211.430 1.00 51.81  ? 486 SER   A CB     1 
ATOM   7904 O OG     . SER   F 1 474 ? 227.878 266.236 210.796 1.00 61.12  ? 486 SER   A OG     1 
ATOM   7905 N N      . TYR   F 1 475 ? 231.466 266.769 210.442 1.00 57.13  ? 487 TYR   A N      1 
ATOM   7906 C CA     . TYR   F 1 475 ? 232.494 265.762 210.677 1.00 53.86  ? 487 TYR   A CA     1 
ATOM   7907 C C      . TYR   F 1 475 ? 233.856 266.437 210.627 1.00 51.49  ? 487 TYR   A C      1 
ATOM   7908 O O      . TYR   F 1 475 ? 234.226 267.017 209.602 1.00 51.98  ? 487 TYR   A O      1 
ATOM   7909 C CB     . TYR   F 1 475 ? 232.414 264.647 209.633 1.00 55.17  ? 487 TYR   A CB     1 
ATOM   7910 C CG     . TYR   F 1 475 ? 231.209 263.740 209.757 1.00 58.10  ? 487 TYR   A CG     1 
ATOM   7911 C CD1    . TYR   F 1 475 ? 230.037 264.180 210.354 1.00 60.46  ? 487 TYR   A CD1    1 
ATOM   7912 C CD2    . TYR   F 1 475 ? 231.235 262.454 209.250 1.00 61.78  ? 487 TYR   A CD2    1 
ATOM   7913 C CE1    . TYR   F 1 475 ? 228.936 263.357 210.458 1.00 59.45  ? 487 TYR   A CE1    1 
ATOM   7914 C CE2    . TYR   F 1 475 ? 230.138 261.625 209.348 1.00 65.96  ? 487 TYR   A CE2    1 
ATOM   7915 C CZ     . TYR   F 1 475 ? 228.992 262.082 209.953 1.00 65.09  ? 487 TYR   A CZ     1 
ATOM   7916 O OH     . TYR   F 1 475 ? 227.897 261.258 210.053 1.00 77.81  ? 487 TYR   A OH     1 
ATOM   7917 N N      . PHE   F 1 476 ? 234.600 266.356 211.731 1.00 50.72  ? 488 PHE   A N      1 
ATOM   7918 C CA     . PHE   F 1 476 ? 235.917 266.980 211.782 1.00 50.72  ? 488 PHE   A CA     1 
ATOM   7919 C C      . PHE   F 1 476 ? 236.895 266.270 210.853 1.00 49.32  ? 488 PHE   A C      1 
ATOM   7920 O O      . PHE   F 1 476 ? 237.596 266.911 210.061 1.00 46.26  ? 488 PHE   A O      1 
ATOM   7921 C CB     . PHE   F 1 476 ? 236.430 266.983 213.222 1.00 45.29  ? 488 PHE   A CB     1 
ATOM   7922 C CG     . PHE   F 1 476 ? 237.658 267.819 213.433 1.00 46.84  ? 488 PHE   A CG     1 
ATOM   7923 C CD1    . PHE   F 1 476 ? 237.663 269.163 213.111 1.00 47.83  ? 488 PHE   A CD1    1 
ATOM   7924 C CD2    . PHE   F 1 476 ? 238.805 267.262 213.970 1.00 48.29  ? 488 PHE   A CD2    1 
ATOM   7925 C CE1    . PHE   F 1 476 ? 238.790 269.933 213.312 1.00 45.22  ? 488 PHE   A CE1    1 
ATOM   7926 C CE2    . PHE   F 1 476 ? 239.935 268.028 214.170 1.00 45.26  ? 488 PHE   A CE2    1 
ATOM   7927 C CZ     . PHE   F 1 476 ? 239.927 269.364 213.843 1.00 41.07  ? 488 PHE   A CZ     1 
ATOM   7928 N N      . PHE   F 1 477 ? 236.953 264.947 210.934 1.00 48.92  ? 489 PHE   A N      1 
ATOM   7929 C CA     . PHE   F 1 477 ? 237.825 264.134 210.085 1.00 50.18  ? 489 PHE   A CA     1 
ATOM   7930 C C      . PHE   F 1 477 ? 237.076 263.600 208.870 1.00 55.58  ? 489 PHE   A C      1 
ATOM   7931 O O      . PHE   F 1 477 ? 236.994 262.393 208.654 1.00 62.89  ? 489 PHE   A O      1 
ATOM   7932 C CB     . PHE   F 1 477 ? 238.425 262.995 210.898 1.00 51.78  ? 489 PHE   A CB     1 
ATOM   7933 C CG     . PHE   F 1 477 ? 239.375 263.449 211.966 1.00 51.70  ? 489 PHE   A CG     1 
ATOM   7934 C CD1    . PHE   F 1 477 ? 240.549 264.098 211.637 1.00 53.18  ? 489 PHE   A CD1    1 
ATOM   7935 C CD2    . PHE   F 1 477 ? 239.089 263.232 213.300 1.00 53.54  ? 489 PHE   A CD2    1 
ATOM   7936 C CE1    . PHE   F 1 477 ? 241.422 264.516 212.618 1.00 50.29  ? 489 PHE   A CE1    1 
ATOM   7937 C CE2    . PHE   F 1 477 ? 239.959 263.650 214.285 1.00 53.62  ? 489 PHE   A CE2    1 
ATOM   7938 C CZ     . PHE   F 1 477 ? 241.126 264.293 213.942 1.00 49.20  ? 489 PHE   A CZ     1 
ATOM   7939 N N      . GLY   F 1 478 ? 236.522 264.494 208.058 1.00 48.29  ? 490 GLY   A N      1 
ATOM   7940 C CA     . GLY   F 1 478 ? 235.754 264.085 206.897 1.00 47.72  ? 490 GLY   A CA     1 
ATOM   7941 C C      . GLY   F 1 478 ? 235.916 265.000 205.700 1.00 53.31  ? 490 GLY   A C      1 
ATOM   7942 O O      . GLY   F 1 478 ? 235.854 264.552 204.555 1.00 48.34  ? 490 GLY   A O      1 
HETATM 7943 C C1     . A1IJK G 3 .   ? 257.558 244.149 239.026 1.00 67.97  ? 101 A1IJK D C1     1 
HETATM 7944 C C2     . A1IJK G 3 .   ? 258.905 243.654 239.478 1.00 65.82  ? 101 A1IJK D C2     1 
HETATM 7945 C C3     . A1IJK G 3 .   ? 259.735 244.741 240.125 1.00 64.91  ? 101 A1IJK D C3     1 
HETATM 7946 C C6     . A1IJK G 3 .   ? 259.793 246.221 242.001 1.00 61.41  ? 101 A1IJK D C6     1 
HETATM 7947 C C7     . A1IJK G 3 .   ? 258.938 246.759 243.128 1.00 61.16  ? 101 A1IJK D C7     1 
HETATM 7948 O O4     . A1IJK G 3 .   ? 259.034 245.295 241.232 1.00 62.44  ? 101 A1IJK D O4     1 
HETATM 7949 O O5     . A1IJK G 3 .   ? 259.602 243.140 238.345 1.00 64.84  ? 101 A1IJK D O5     1 
HETATM 7950 C C8     . A1IJK G 3 .   ? 259.718 247.441 244.237 1.00 59.58  ? 101 A1IJK D C8     1 
HETATM 7951 C C10    . A1IJK G 3 .   ? 259.489 249.700 243.343 1.00 53.87  ? 101 A1IJK D C10    1 
HETATM 7952 N N9     . A1IJK G 3 .   ? 260.259 248.731 243.835 1.00 54.47  ? 101 A1IJK D N9     1 
HETATM 7953 C C33    . A1IJK G 3 .   ? 262.288 254.731 239.430 1.00 49.27  ? 101 A1IJK D C33    1 
HETATM 7954 C C34    . A1IJK G 3 .   ? 261.523 254.362 240.496 1.00 48.79  ? 101 A1IJK D C34    1 
HETATM 7955 C C11    . A1IJK G 3 .   ? 259.978 251.112 243.503 1.00 50.91  ? 101 A1IJK D C11    1 
HETATM 7956 C C12    . A1IJK G 3 .   ? 260.892 251.465 244.485 1.00 46.87  ? 101 A1IJK D C12    1 
HETATM 7957 C C13    . A1IJK G 3 .   ? 261.320 252.772 244.599 1.00 45.95  ? 101 A1IJK D C13    1 
HETATM 7958 C C14    . A1IJK G 3 .   ? 260.864 253.761 243.735 1.00 46.48  ? 101 A1IJK D C14    1 
HETATM 7959 C C15    . A1IJK G 3 .   ? 259.933 253.410 242.739 1.00 47.79  ? 101 A1IJK D C15    1 
HETATM 7960 C C16    . A1IJK G 3 .   ? 259.514 252.089 242.631 1.00 50.82  ? 101 A1IJK D C16    1 
HETATM 7961 C C17    . A1IJK G 3 .   ? 261.384 255.167 243.923 1.00 47.23  ? 101 A1IJK D C17    1 
HETATM 7962 C C20    . A1IJK G 3 .   ? 259.399 254.395 241.752 1.00 48.48  ? 101 A1IJK D C20    1 
HETATM 7963 C C21    . A1IJK G 3 .   ? 258.046 254.920 241.831 1.00 49.60  ? 101 A1IJK D C21    1 
HETATM 7964 C C22    . A1IJK G 3 .   ? 257.553 255.722 240.771 1.00 47.75  ? 101 A1IJK D C22    1 
HETATM 7965 C C24    . A1IJK G 3 .   ? 259.663 255.663 239.645 1.00 47.59  ? 101 A1IJK D C24    1 
HETATM 7966 C C25    . A1IJK G 3 .   ? 260.213 254.812 240.624 1.00 49.05  ? 101 A1IJK D C25    1 
HETATM 7967 C C27    . A1IJK G 3 .   ? 256.224 256.115 240.770 1.00 47.75  ? 101 A1IJK D C27    1 
HETATM 7968 C C28    . A1IJK G 3 .   ? 255.351 255.748 241.862 1.00 49.13  ? 101 A1IJK D C28    1 
HETATM 7969 C C29    . A1IJK G 3 .   ? 255.920 255.043 242.967 1.00 50.59  ? 101 A1IJK D C29    1 
HETATM 7970 C C30    . A1IJK G 3 .   ? 257.246 254.646 242.940 1.00 50.10  ? 101 A1IJK D C30    1 
HETATM 7971 C C31    . A1IJK G 3 .   ? 260.456 256.047 238.568 1.00 46.34  ? 101 A1IJK D C31    1 
HETATM 7972 C C32    . A1IJK G 3 .   ? 261.795 255.564 238.446 1.00 47.39  ? 101 A1IJK D C32    1 
HETATM 7973 O O18    . A1IJK G 3 .   ? 260.926 256.068 243.200 1.00 46.80  ? 101 A1IJK D O18    1 
HETATM 7974 O O19    . A1IJK G 3 .   ? 262.252 255.345 244.792 1.00 48.21  ? 101 A1IJK D O19    1 
HETATM 7975 O O23    . A1IJK G 3 .   ? 258.362 256.105 239.726 1.00 47.16  ? 101 A1IJK D O23    1 
HETATM 7976 O O26    . A1IJK G 3 .   ? 258.396 249.469 242.830 1.00 55.65  ? 101 A1IJK D O26    1 
HETATM 7977 O O35    . A1IJK G 3 .   ? 254.152 256.044 241.848 1.00 51.42  ? 101 A1IJK D O35    1 
HETATM 7978 O O36    . A1IJK G 3 .   ? 262.499 255.887 237.483 1.00 47.60  ? 101 A1IJK D O36    1 
HETATM 7979 C C1     . A1IJK H 3 .   ? 256.377 213.149 212.469 1.00 51.84  ? 101 A1IJK E C1     1 
HETATM 7980 C C2     . A1IJK H 3 .   ? 257.379 213.003 213.592 1.00 51.84  ? 101 A1IJK E C2     1 
HETATM 7981 C C3     . A1IJK H 3 .   ? 258.092 214.295 213.919 1.00 51.84  ? 101 A1IJK E C3     1 
HETATM 7982 C C6     . A1IJK H 3 .   ? 259.603 215.290 215.448 1.00 51.84  ? 101 A1IJK E C6     1 
HETATM 7983 C C7     . A1IJK H 3 .   ? 260.395 215.036 216.713 1.00 51.84  ? 101 A1IJK E C7     1 
HETATM 7984 O O4     . A1IJK H 3 .   ? 258.961 214.092 215.028 1.00 51.84  ? 101 A1IJK E O4     1 
HETATM 7985 O O5     . A1IJK H 3 .   ? 258.340 212.015 213.224 1.00 51.84  ? 101 A1IJK E O5     1 
HETATM 7986 C C8     . A1IJK H 3 .   ? 261.629 214.179 216.507 1.00 51.84  ? 101 A1IJK E C8     1 
HETATM 7987 C C10    . A1IJK H 3 .   ? 263.748 214.831 217.499 1.00 51.84  ? 101 A1IJK E C10    1 
HETATM 7988 N N9     . A1IJK H 3 .   ? 262.847 214.976 216.528 1.00 51.84  ? 101 A1IJK E N9     1 
HETATM 7989 C C33    . A1IJK H 3 .   ? 268.353 215.589 212.413 1.00 51.84  ? 101 A1IJK E C33    1 
HETATM 7990 C C34    . A1IJK H 3 .   ? 267.746 216.040 213.547 1.00 51.84  ? 101 A1IJK E C34    1 
HETATM 7991 C C11    . A1IJK H 3 .   ? 265.085 215.489 217.308 1.00 51.84  ? 101 A1IJK E C11    1 
HETATM 7992 C C12    . A1IJK H 3 .   ? 266.103 215.237 218.216 1.00 51.84  ? 101 A1IJK E C12    1 
HETATM 7993 C C13    . A1IJK H 3 .   ? 267.341 215.826 218.058 1.00 51.84  ? 101 A1IJK E C13    1 
HETATM 7994 C C14    . A1IJK H 3 .   ? 267.598 216.689 216.999 1.00 51.84  ? 101 A1IJK E C14    1 
HETATM 7995 C C15    . A1IJK H 3 .   ? 266.568 216.954 216.076 1.00 51.84  ? 101 A1IJK E C15    1 
HETATM 7996 C C16    . A1IJK H 3 .   ? 265.326 216.348 216.241 1.00 51.84  ? 101 A1IJK E C16    1 
HETATM 7997 C C17    . A1IJK H 3 .   ? 268.978 217.296 216.895 1.00 51.84  ? 101 A1IJK E C17    1 
HETATM 7998 C C20    . A1IJK H 3 .   ? 266.768 217.861 214.906 1.00 51.84  ? 101 A1IJK E C20    1 
HETATM 7999 C C21    . A1IJK H 3 .   ? 266.333 219.246 214.936 1.00 51.84  ? 101 A1IJK E C21    1 
HETATM 8000 C C22    . A1IJK H 3 .   ? 266.554 220.067 213.801 1.00 51.84  ? 101 A1IJK E C22    1 
HETATM 8001 C C24    . A1IJK H 3 .   ? 267.611 218.277 212.618 1.00 51.84  ? 101 A1IJK E C24    1 
HETATM 8002 C C25    . A1IJK H 3 .   ? 267.387 217.379 213.682 1.00 51.84  ? 101 A1IJK E C25    1 
HETATM 8003 C C27    . A1IJK H 3 .   ? 266.084 221.372 213.795 1.00 51.84  ? 101 A1IJK E C27    1 
HETATM 8004 C C28    . A1IJK H 3 .   ? 265.359 221.895 214.932 1.00 51.84  ? 101 A1IJK E C28    1 
HETATM 8005 C C29    . A1IJK H 3 .   ? 265.214 221.055 216.079 1.00 51.84  ? 101 A1IJK E C29    1 
HETATM 8006 C C30    . A1IJK H 3 .   ? 265.705 219.761 216.069 1.00 51.84  ? 101 A1IJK E C30    1 
HETATM 8007 C C31    . A1IJK H 3 .   ? 268.254 217.813 211.474 1.00 51.84  ? 101 A1IJK E C31    1 
HETATM 8008 C C32    . A1IJK H 3 .   ? 268.652 216.444 211.371 1.00 51.84  ? 101 A1IJK E C32    1 
HETATM 8009 O O18    . A1IJK H 3 .   ? 269.173 218.171 216.037 1.00 51.84  ? 101 A1IJK E O18    1 
HETATM 8010 O O19    . A1IJK H 3 .   ? 269.850 216.876 217.674 1.00 51.84  ? 101 A1IJK E O19    1 
HETATM 8011 O O23    . A1IJK H 3 .   ? 267.210 219.591 212.688 1.00 51.84  ? 101 A1IJK E O23    1 
HETATM 8012 O O26    . A1IJK H 3 .   ? 263.517 214.164 218.506 1.00 51.84  ? 101 A1IJK E O26    1 
HETATM 8013 O O35    . A1IJK H 3 .   ? 264.887 223.036 214.917 1.00 51.84  ? 101 A1IJK E O35    1 
HETATM 8014 O O36    . A1IJK H 3 .   ? 269.245 216.030 210.370 1.00 51.84  ? 101 A1IJK E O36    1 
# 
