data_9GAS
# 
_entry.id   9GAS 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GAS         pdb_00009gas 10.2210/pdb9gas/pdb 
WWPDB D_1292140614 ?            ?                   
EMDB  EMD-51187    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-15 
2 'Structure model' 1 1 2025-02-12 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 2 'Structure model' em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation.year'           
3 2 'Structure model' '_em_admin.last_update'    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GAS 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-29 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'focused map on Strand 1 of the double stranded antiparallel helical assembly with 18mer RNA'                          
EMD-51189 'other EM volume'      
EMDB 'global map of the double stranded parallel helical assembly with 14mer RNA'                                           
EMD-51186 'other EM volume'      
EMDB 'map of the double stranded parallel helical assembly with 12mer RNA'                                                  
EMD-51185 'other EM volume'      
EMDB 'map of the single stranded helical assembly with 12mer RNA'                                                           
EMD-51184 'other EM volume'      
EMDB 'global map of the double stranded antiparallel helical assembly with 18mer RNA'                                       
EMD-51188 'other EM volume'      
EMDB 'Focused reconstruction on strand 2 of the influenza A RNP-like particle double-stranded assembled with a 18-mer RNA.' 
EMD-51187 'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 thibaut.crepin@ibs.fr           Thibaut Crepin           ? 'principal investigator/group leader' 0000-0003-2663-1794 
3 allison.ballandras-colas@ibs.fr Allison Ballandras-Colas ? 'principal investigator/group leader' 0000-0003-4735-4984 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Chenavier, F.'        1 0000-0002-9486-3944 
'Ruigrok, R.W.H.'      2 0000-0002-8094-6642 
'Schoehn, G.'          3 0000-0002-1459-3201 
'Ballandras-Colas, A.' 4 0000-0003-4735-4984 
'Crepin, T.'           5 0000-0003-2663-1794 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nucleic Acids Res.' 
_citation.journal_id_ASTM           NARHAD 
_citation.journal_id_CSD            0389 
_citation.journal_id_ISSN           1362-4962 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            53 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Influenza a virus antiparallel helical nucleocapsid-like pseudo-atomic structure.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1093/nar/gkae1211 
_citation.pdbx_database_id_PubMed   39673795 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chenavier, F.'        1 0000-0002-9486-3944 
primary 'Zarkadas, E.'         2 0000-0002-9276-9831 
primary 'Freslon, L.L.'        3 ?                   
primary 'Stelfox, A.J.'        4 0000-0003-4553-6565 
primary 'Schoehn, G.'          5 0000-0002-1459-3201 
primary 'Ruigrok, R.W.H.'      6 0000-0002-8094-6642 
primary 'Ballandras-Colas, A.' 7 0000-0003-4735-4984 
primary 'Crepin, T.'           8 0000-0003-2663-1794 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     syn 
;RNA (5'-P(UC)9-FAM3')
;
5457.170  2 ? ? ? ? 
2 polymer     man Nucleoprotein                                                                                                  
56150.395 2 ? ? ? ? 
3 non-polymer syn '2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2R)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid' 
493.505   1 ? ? ? ? 
# 
_entity_name_com.entity_id   2 
_entity_name_com.name        'Nucleocapsid protein,Protein N' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 polyribonucleotide no no UCUCUCUCUCUCUCUCUC UCUCUCUCUCUCUCUCUC D,C ? 
2 'polypeptide(L)'   no no 
;HMTDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKT
GGPIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTL
PRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAE
FEDLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMA
CHSAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTF
SVQRNLPFDRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDN
AEEYDNLEHHHHHH
;
;HMTDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKT
GGPIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTL
PRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAE
FEDLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMA
CHSAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTF
SVQRNLPFDRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDN
AEEYDNLEHHHHHH
;
B,A ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        
'2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2R)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid' 
_pdbx_entity_nonpoly.comp_id     A1IJK 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   U   n 
1 2   C   n 
1 3   U   n 
1 4   C   n 
1 5   U   n 
1 6   C   n 
1 7   U   n 
1 8   C   n 
1 9   U   n 
1 10  C   n 
1 11  U   n 
1 12  C   n 
1 13  U   n 
1 14  C   n 
1 15  U   n 
1 16  C   n 
1 17  U   n 
1 18  C   n 
2 1   HIS n 
2 2   MET n 
2 3   THR n 
2 4   ASP n 
2 5   GLY n 
2 6   GLU n 
2 7   ARG n 
2 8   GLN n 
2 9   ASN n 
2 10  ALA n 
2 11  THR n 
2 12  GLU n 
2 13  ILE n 
2 14  ARG n 
2 15  ALA n 
2 16  SER n 
2 17  VAL n 
2 18  GLY n 
2 19  LYS n 
2 20  MET n 
2 21  ILE n 
2 22  ASP n 
2 23  GLY n 
2 24  ILE n 
2 25  GLY n 
2 26  ARG n 
2 27  PHE n 
2 28  TYR n 
2 29  ILE n 
2 30  GLN n 
2 31  MET n 
2 32  CYS n 
2 33  THR n 
2 34  GLU n 
2 35  LEU n 
2 36  LYS n 
2 37  LEU n 
2 38  SER n 
2 39  ASP n 
2 40  TYR n 
2 41  GLU n 
2 42  GLY n 
2 43  ARG n 
2 44  LEU n 
2 45  ILE n 
2 46  GLN n 
2 47  ASN n 
2 48  SER n 
2 49  LEU n 
2 50  THR n 
2 51  ILE n 
2 52  GLU n 
2 53  ARG n 
2 54  MET n 
2 55  VAL n 
2 56  LEU n 
2 57  SER n 
2 58  ALA n 
2 59  PHE n 
2 60  ASP n 
2 61  GLU n 
2 62  ARG n 
2 63  ARG n 
2 64  ASN n 
2 65  LYS n 
2 66  TYR n 
2 67  LEU n 
2 68  GLU n 
2 69  GLU n 
2 70  HIS n 
2 71  PRO n 
2 72  SER n 
2 73  ALA n 
2 74  GLY n 
2 75  LYS n 
2 76  ASP n 
2 77  PRO n 
2 78  LYS n 
2 79  LYS n 
2 80  THR n 
2 81  GLY n 
2 82  GLY n 
2 83  PRO n 
2 84  ILE n 
2 85  TYR n 
2 86  ARG n 
2 87  ARG n 
2 88  VAL n 
2 89  ASP n 
2 90  GLY n 
2 91  LYS n 
2 92  TRP n 
2 93  ARG n 
2 94  ARG n 
2 95  GLU n 
2 96  LEU n 
2 97  ILE n 
2 98  LEU n 
2 99  TYR n 
2 100 ASP n 
2 101 LYS n 
2 102 GLU n 
2 103 GLU n 
2 104 ILE n 
2 105 ARG n 
2 106 ARG n 
2 107 ILE n 
2 108 TRP n 
2 109 ARG n 
2 110 GLN n 
2 111 ALA n 
2 112 ASN n 
2 113 ASN n 
2 114 GLY n 
2 115 ASP n 
2 116 ASP n 
2 117 ALA n 
2 118 THR n 
2 119 ALA n 
2 120 GLY n 
2 121 LEU n 
2 122 THR n 
2 123 HIS n 
2 124 MET n 
2 125 MET n 
2 126 ILE n 
2 127 TRP n 
2 128 HIS n 
2 129 SER n 
2 130 ASN n 
2 131 LEU n 
2 132 ASN n 
2 133 ASP n 
2 134 ALA n 
2 135 THR n 
2 136 TYR n 
2 137 GLN n 
2 138 ARG n 
2 139 THR n 
2 140 ARG n 
2 141 ALA n 
2 142 LEU n 
2 143 VAL n 
2 144 ARG n 
2 145 THR n 
2 146 GLY n 
2 147 MET n 
2 148 ASP n 
2 149 PRO n 
2 150 ARG n 
2 151 MET n 
2 152 CYS n 
2 153 SER n 
2 154 LEU n 
2 155 MET n 
2 156 GLN n 
2 157 GLY n 
2 158 SER n 
2 159 THR n 
2 160 LEU n 
2 161 PRO n 
2 162 ARG n 
2 163 ARG n 
2 164 SER n 
2 165 GLY n 
2 166 ALA n 
2 167 ALA n 
2 168 GLY n 
2 169 ALA n 
2 170 ALA n 
2 171 VAL n 
2 172 LYS n 
2 173 GLY n 
2 174 VAL n 
2 175 GLY n 
2 176 THR n 
2 177 MET n 
2 178 VAL n 
2 179 MET n 
2 180 GLU n 
2 181 LEU n 
2 182 ILE n 
2 183 ARG n 
2 184 MET n 
2 185 ILE n 
2 186 LYS n 
2 187 ARG n 
2 188 GLY n 
2 189 ILE n 
2 190 ASN n 
2 191 ASP n 
2 192 ARG n 
2 193 ASN n 
2 194 PHE n 
2 195 TRP n 
2 196 ARG n 
2 197 GLY n 
2 198 GLU n 
2 199 ASN n 
2 200 GLY n 
2 201 ARG n 
2 202 ARG n 
2 203 THR n 
2 204 ARG n 
2 205 ILE n 
2 206 ALA n 
2 207 TYR n 
2 208 GLU n 
2 209 ARG n 
2 210 MET n 
2 211 CYS n 
2 212 ASN n 
2 213 ILE n 
2 214 LEU n 
2 215 LYS n 
2 216 GLY n 
2 217 LYS n 
2 218 PHE n 
2 219 GLN n 
2 220 THR n 
2 221 ALA n 
2 222 ALA n 
2 223 GLN n 
2 224 ARG n 
2 225 THR n 
2 226 MET n 
2 227 VAL n 
2 228 ASP n 
2 229 GLN n 
2 230 VAL n 
2 231 ARG n 
2 232 GLU n 
2 233 SER n 
2 234 ARG n 
2 235 ASN n 
2 236 PRO n 
2 237 GLY n 
2 238 ASN n 
2 239 ALA n 
2 240 GLU n 
2 241 PHE n 
2 242 GLU n 
2 243 ASP n 
2 244 LEU n 
2 245 ILE n 
2 246 PHE n 
2 247 LEU n 
2 248 ALA n 
2 249 ARG n 
2 250 SER n 
2 251 ALA n 
2 252 LEU n 
2 253 ILE n 
2 254 LEU n 
2 255 ARG n 
2 256 GLY n 
2 257 SER n 
2 258 VAL n 
2 259 ALA n 
2 260 HIS n 
2 261 LYS n 
2 262 SER n 
2 263 CYS n 
2 264 LEU n 
2 265 PRO n 
2 266 ALA n 
2 267 CYS n 
2 268 VAL n 
2 269 TYR n 
2 270 GLY n 
2 271 SER n 
2 272 ALA n 
2 273 VAL n 
2 274 ALA n 
2 275 SER n 
2 276 GLY n 
2 277 TYR n 
2 278 ASP n 
2 279 PHE n 
2 280 GLU n 
2 281 ARG n 
2 282 GLU n 
2 283 GLY n 
2 284 TYR n 
2 285 SER n 
2 286 LEU n 
2 287 VAL n 
2 288 GLY n 
2 289 ILE n 
2 290 ASP n 
2 291 PRO n 
2 292 PHE n 
2 293 ARG n 
2 294 LEU n 
2 295 LEU n 
2 296 GLN n 
2 297 ASN n 
2 298 SER n 
2 299 GLN n 
2 300 VAL n 
2 301 TYR n 
2 302 SER n 
2 303 LEU n 
2 304 ILE n 
2 305 ARG n 
2 306 PRO n 
2 307 ASN n 
2 308 GLU n 
2 309 ASN n 
2 310 PRO n 
2 311 ALA n 
2 312 HIS n 
2 313 LYS n 
2 314 SER n 
2 315 GLN n 
2 316 LEU n 
2 317 VAL n 
2 318 TRP n 
2 319 MET n 
2 320 ALA n 
2 321 CYS n 
2 322 HIS n 
2 323 SER n 
2 324 ALA n 
2 325 ALA n 
2 326 PHE n 
2 327 GLU n 
2 328 ASP n 
2 329 LEU n 
2 330 ARG n 
2 331 VAL n 
2 332 SER n 
2 333 SER n 
2 334 PHE n 
2 335 ILE n 
2 336 ARG n 
2 337 GLY n 
2 338 THR n 
2 339 LYS n 
2 340 VAL n 
2 341 VAL n 
2 342 PRO n 
2 343 ARG n 
2 344 GLY n 
2 345 LYS n 
2 346 LEU n 
2 347 SER n 
2 348 THR n 
2 349 ARG n 
2 350 GLY n 
2 351 VAL n 
2 352 GLN n 
2 353 ILE n 
2 354 ALA n 
2 355 SER n 
2 356 ASN n 
2 357 GLU n 
2 358 ASN n 
2 359 MET n 
2 360 GLU n 
2 361 THR n 
2 362 MET n 
2 363 GLU n 
2 364 SER n 
2 365 SER n 
2 366 THR n 
2 367 LEU n 
2 368 GLU n 
2 369 LEU n 
2 370 ARG n 
2 371 SER n 
2 372 ARG n 
2 373 TYR n 
2 374 TRP n 
2 375 ALA n 
2 376 ILE n 
2 377 ARG n 
2 378 THR n 
2 379 ARG n 
2 380 SER n 
2 381 GLY n 
2 382 GLY n 
2 383 ASN n 
2 384 THR n 
2 385 ASN n 
2 386 GLN n 
2 387 GLN n 
2 388 ARG n 
2 389 ALA n 
2 390 SER n 
2 391 SER n 
2 392 GLY n 
2 393 GLN n 
2 394 ILE n 
2 395 SER n 
2 396 ILE n 
2 397 GLN n 
2 398 PRO n 
2 399 THR n 
2 400 PHE n 
2 401 SER n 
2 402 VAL n 
2 403 GLN n 
2 404 ARG n 
2 405 ASN n 
2 406 LEU n 
2 407 PRO n 
2 408 PHE n 
2 409 ASP n 
2 410 ARG n 
2 411 PRO n 
2 412 THR n 
2 413 ILE n 
2 414 MET n 
2 415 ALA n 
2 416 ALA n 
2 417 PHE n 
2 418 THR n 
2 419 GLY n 
2 420 ASN n 
2 421 THR n 
2 422 GLU n 
2 423 GLY n 
2 424 ARG n 
2 425 THR n 
2 426 SER n 
2 427 ASP n 
2 428 MET n 
2 429 ARG n 
2 430 THR n 
2 431 GLU n 
2 432 ILE n 
2 433 ILE n 
2 434 ARG n 
2 435 LEU n 
2 436 MET n 
2 437 GLU n 
2 438 SER n 
2 439 ALA n 
2 440 ARG n 
2 441 PRO n 
2 442 GLU n 
2 443 ASP n 
2 444 VAL n 
2 445 SER n 
2 446 PHE n 
2 447 GLN n 
2 448 GLY n 
2 449 ARG n 
2 450 GLY n 
2 451 VAL n 
2 452 PHE n 
2 453 GLU n 
2 454 LEU n 
2 455 SER n 
2 456 ASP n 
2 457 GLU n 
2 458 LYS n 
2 459 ALA n 
2 460 THR n 
2 461 SER n 
2 462 PRO n 
2 463 ILE n 
2 464 VAL n 
2 465 PRO n 
2 466 SER n 
2 467 PHE n 
2 468 ASP n 
2 469 MET n 
2 470 SER n 
2 471 ASN n 
2 472 GLU n 
2 473 GLY n 
2 474 SER n 
2 475 TYR n 
2 476 PHE n 
2 477 PHE n 
2 478 GLY n 
2 479 ASP n 
2 480 ASN n 
2 481 ALA n 
2 482 GLU n 
2 483 GLU n 
2 484 TYR n 
2 485 ASP n 
2 486 ASN n 
2 487 LEU n 
2 488 GLU n 
2 489 HIS n 
2 490 HIS n 
2 491 HIS n 
2 492 HIS n 
2 493 HIS n 
2 494 HIS n 
# 
_entity_src_gen.entity_id                          2 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   494 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 NP 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Influenza A virus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     11320 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              1 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       18 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1IJK non-polymer         . 
'2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2R)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid' ? 'C27 H27 N O8'   
493.505 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
C     'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE" ? 'C9 H14 N3 O8 P' 323.197 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'    181.189 
U     'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE" ? 'C9 H13 N2 O9 P' 324.181 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   U   1   1   1   U   U   D . n 
A 1 2   C   2   2   2   C   C   D . n 
A 1 3   U   3   3   3   U   U   D . n 
A 1 4   C   4   4   4   C   C   D . n 
A 1 5   U   5   5   5   U   U   D . n 
A 1 6   C   6   6   6   C   C   D . n 
A 1 7   U   7   7   7   U   U   D . n 
A 1 8   C   8   8   ?   ?   ?   D . n 
A 1 9   U   9   9   ?   ?   ?   D . n 
A 1 10  C   10  10  ?   ?   ?   D . n 
A 1 11  U   11  11  ?   ?   ?   D . n 
A 1 12  C   12  12  ?   ?   ?   D . n 
A 1 13  U   13  13  ?   ?   ?   D . n 
A 1 14  C   14  14  ?   ?   ?   D . n 
A 1 15  U   15  15  ?   ?   ?   D . n 
A 1 16  C   16  16  ?   ?   ?   D . n 
A 1 17  U   17  17  ?   ?   ?   D . n 
A 1 18  C   18  18  ?   ?   ?   D . n 
B 1 1   U   1   7   ?   ?   ?   C . n 
B 1 2   C   2   8   8   C   C   C . n 
B 1 3   U   3   9   9   U   U   C . n 
B 1 4   C   4   10  10  C   C   C . n 
B 1 5   U   5   11  11  U   U   C . n 
B 1 6   C   6   12  12  C   C   C . n 
B 1 7   U   7   13  13  U   U   C . n 
B 1 8   C   8   14  14  C   C   C . n 
B 1 9   U   9   15  15  U   U   C . n 
B 1 10  C   10  16  16  C   C   C . n 
B 1 11  U   11  17  17  U   U   C . n 
B 1 12  C   12  18  18  C   6FM C . n 
B 1 13  U   13  19  ?   ?   ?   C . n 
B 1 14  C   14  20  ?   ?   ?   C . n 
B 1 15  U   15  21  ?   ?   ?   C . n 
B 1 16  C   16  22  ?   ?   ?   C . n 
B 1 17  U   17  23  ?   ?   ?   C . n 
B 1 18  C   18  24  ?   ?   ?   C . n 
C 2 1   HIS 1   13  ?   ?   ?   B . n 
C 2 2   MET 2   14  ?   ?   ?   B . n 
C 2 3   THR 3   15  ?   ?   ?   B . n 
C 2 4   ASP 4   16  ?   ?   ?   B . n 
C 2 5   GLY 5   17  ?   ?   ?   B . n 
C 2 6   GLU 6   18  ?   ?   ?   B . n 
C 2 7   ARG 7   19  ?   ?   ?   B . n 
C 2 8   GLN 8   20  ?   ?   ?   B . n 
C 2 9   ASN 9   21  ?   ?   ?   B . n 
C 2 10  ALA 10  22  ?   ?   ?   B . n 
C 2 11  THR 11  23  ?   ?   ?   B . n 
C 2 12  GLU 12  24  ?   ?   ?   B . n 
C 2 13  ILE 13  25  ?   ?   ?   B . n 
C 2 14  ARG 14  26  ?   ?   ?   B . n 
C 2 15  ALA 15  27  ?   ?   ?   B . n 
C 2 16  SER 16  28  ?   ?   ?   B . n 
C 2 17  VAL 17  29  ?   ?   ?   B . n 
C 2 18  GLY 18  30  ?   ?   ?   B . n 
C 2 19  LYS 19  31  ?   ?   ?   B . n 
C 2 20  MET 20  32  ?   ?   ?   B . n 
C 2 21  ILE 21  33  ?   ?   ?   B . n 
C 2 22  ASP 22  34  ?   ?   ?   B . n 
C 2 23  GLY 23  35  ?   ?   ?   B . n 
C 2 24  ILE 24  36  ?   ?   ?   B . n 
C 2 25  GLY 25  37  ?   ?   ?   B . n 
C 2 26  ARG 26  38  ?   ?   ?   B . n 
C 2 27  PHE 27  39  ?   ?   ?   B . n 
C 2 28  TYR 28  40  ?   ?   ?   B . n 
C 2 29  ILE 29  41  ?   ?   ?   B . n 
C 2 30  GLN 30  42  ?   ?   ?   B . n 
C 2 31  MET 31  43  ?   ?   ?   B . n 
C 2 32  CYS 32  44  ?   ?   ?   B . n 
C 2 33  THR 33  45  ?   ?   ?   B . n 
C 2 34  GLU 34  46  ?   ?   ?   B . n 
C 2 35  LEU 35  47  ?   ?   ?   B . n 
C 2 36  LYS 36  48  ?   ?   ?   B . n 
C 2 37  LEU 37  49  ?   ?   ?   B . n 
C 2 38  SER 38  50  ?   ?   ?   B . n 
C 2 39  ASP 39  51  ?   ?   ?   B . n 
C 2 40  TYR 40  52  ?   ?   ?   B . n 
C 2 41  GLU 41  53  ?   ?   ?   B . n 
C 2 42  GLY 42  54  ?   ?   ?   B . n 
C 2 43  ARG 43  55  ?   ?   ?   B . n 
C 2 44  LEU 44  56  ?   ?   ?   B . n 
C 2 45  ILE 45  57  ?   ?   ?   B . n 
C 2 46  GLN 46  58  ?   ?   ?   B . n 
C 2 47  ASN 47  59  ?   ?   ?   B . n 
C 2 48  SER 48  60  ?   ?   ?   B . n 
C 2 49  LEU 49  61  ?   ?   ?   B . n 
C 2 50  THR 50  62  ?   ?   ?   B . n 
C 2 51  ILE 51  63  ?   ?   ?   B . n 
C 2 52  GLU 52  64  ?   ?   ?   B . n 
C 2 53  ARG 53  65  ?   ?   ?   B . n 
C 2 54  MET 54  66  ?   ?   ?   B . n 
C 2 55  VAL 55  67  ?   ?   ?   B . n 
C 2 56  LEU 56  68  ?   ?   ?   B . n 
C 2 57  SER 57  69  ?   ?   ?   B . n 
C 2 58  ALA 58  70  ?   ?   ?   B . n 
C 2 59  PHE 59  71  ?   ?   ?   B . n 
C 2 60  ASP 60  72  ?   ?   ?   B . n 
C 2 61  GLU 61  73  ?   ?   ?   B . n 
C 2 62  ARG 62  74  ?   ?   ?   B . n 
C 2 63  ARG 63  75  ?   ?   ?   B . n 
C 2 64  ASN 64  76  ?   ?   ?   B . n 
C 2 65  LYS 65  77  ?   ?   ?   B . n 
C 2 66  TYR 66  78  ?   ?   ?   B . n 
C 2 67  LEU 67  79  ?   ?   ?   B . n 
C 2 68  GLU 68  80  ?   ?   ?   B . n 
C 2 69  GLU 69  81  ?   ?   ?   B . n 
C 2 70  HIS 70  82  ?   ?   ?   B . n 
C 2 71  PRO 71  83  ?   ?   ?   B . n 
C 2 72  SER 72  84  ?   ?   ?   B . n 
C 2 73  ALA 73  85  ?   ?   ?   B . n 
C 2 74  GLY 74  86  ?   ?   ?   B . n 
C 2 75  LYS 75  87  ?   ?   ?   B . n 
C 2 76  ASP 76  88  ?   ?   ?   B . n 
C 2 77  PRO 77  89  ?   ?   ?   B . n 
C 2 78  LYS 78  90  ?   ?   ?   B . n 
C 2 79  LYS 79  91  ?   ?   ?   B . n 
C 2 80  THR 80  92  ?   ?   ?   B . n 
C 2 81  GLY 81  93  ?   ?   ?   B . n 
C 2 82  GLY 82  94  ?   ?   ?   B . n 
C 2 83  PRO 83  95  ?   ?   ?   B . n 
C 2 84  ILE 84  96  ?   ?   ?   B . n 
C 2 85  TYR 85  97  ?   ?   ?   B . n 
C 2 86  ARG 86  98  ?   ?   ?   B . n 
C 2 87  ARG 87  99  ?   ?   ?   B . n 
C 2 88  VAL 88  100 ?   ?   ?   B . n 
C 2 89  ASP 89  101 ?   ?   ?   B . n 
C 2 90  GLY 90  102 ?   ?   ?   B . n 
C 2 91  LYS 91  103 ?   ?   ?   B . n 
C 2 92  TRP 92  104 ?   ?   ?   B . n 
C 2 93  ARG 93  105 ?   ?   ?   B . n 
C 2 94  ARG 94  106 ?   ?   ?   B . n 
C 2 95  GLU 95  107 ?   ?   ?   B . n 
C 2 96  LEU 96  108 ?   ?   ?   B . n 
C 2 97  ILE 97  109 ?   ?   ?   B . n 
C 2 98  LEU 98  110 ?   ?   ?   B . n 
C 2 99  TYR 99  111 ?   ?   ?   B . n 
C 2 100 ASP 100 112 ?   ?   ?   B . n 
C 2 101 LYS 101 113 ?   ?   ?   B . n 
C 2 102 GLU 102 114 ?   ?   ?   B . n 
C 2 103 GLU 103 115 ?   ?   ?   B . n 
C 2 104 ILE 104 116 ?   ?   ?   B . n 
C 2 105 ARG 105 117 ?   ?   ?   B . n 
C 2 106 ARG 106 118 ?   ?   ?   B . n 
C 2 107 ILE 107 119 ?   ?   ?   B . n 
C 2 108 TRP 108 120 ?   ?   ?   B . n 
C 2 109 ARG 109 121 ?   ?   ?   B . n 
C 2 110 GLN 110 122 ?   ?   ?   B . n 
C 2 111 ALA 111 123 ?   ?   ?   B . n 
C 2 112 ASN 112 124 ?   ?   ?   B . n 
C 2 113 ASN 113 125 ?   ?   ?   B . n 
C 2 114 GLY 114 126 ?   ?   ?   B . n 
C 2 115 ASP 115 127 ?   ?   ?   B . n 
C 2 116 ASP 116 128 ?   ?   ?   B . n 
C 2 117 ALA 117 129 ?   ?   ?   B . n 
C 2 118 THR 118 130 ?   ?   ?   B . n 
C 2 119 ALA 119 131 ?   ?   ?   B . n 
C 2 120 GLY 120 132 ?   ?   ?   B . n 
C 2 121 LEU 121 133 ?   ?   ?   B . n 
C 2 122 THR 122 134 ?   ?   ?   B . n 
C 2 123 HIS 123 135 ?   ?   ?   B . n 
C 2 124 MET 124 136 ?   ?   ?   B . n 
C 2 125 MET 125 137 ?   ?   ?   B . n 
C 2 126 ILE 126 138 ?   ?   ?   B . n 
C 2 127 TRP 127 139 ?   ?   ?   B . n 
C 2 128 HIS 128 140 ?   ?   ?   B . n 
C 2 129 SER 129 141 ?   ?   ?   B . n 
C 2 130 ASN 130 142 ?   ?   ?   B . n 
C 2 131 LEU 131 143 ?   ?   ?   B . n 
C 2 132 ASN 132 144 ?   ?   ?   B . n 
C 2 133 ASP 133 145 ?   ?   ?   B . n 
C 2 134 ALA 134 146 ?   ?   ?   B . n 
C 2 135 THR 135 147 ?   ?   ?   B . n 
C 2 136 TYR 136 148 ?   ?   ?   B . n 
C 2 137 GLN 137 149 ?   ?   ?   B . n 
C 2 138 ARG 138 150 ?   ?   ?   B . n 
C 2 139 THR 139 151 ?   ?   ?   B . n 
C 2 140 ARG 140 152 ?   ?   ?   B . n 
C 2 141 ALA 141 153 ?   ?   ?   B . n 
C 2 142 LEU 142 154 ?   ?   ?   B . n 
C 2 143 VAL 143 155 ?   ?   ?   B . n 
C 2 144 ARG 144 156 ?   ?   ?   B . n 
C 2 145 THR 145 157 ?   ?   ?   B . n 
C 2 146 GLY 146 158 ?   ?   ?   B . n 
C 2 147 MET 147 159 ?   ?   ?   B . n 
C 2 148 ASP 148 160 ?   ?   ?   B . n 
C 2 149 PRO 149 161 ?   ?   ?   B . n 
C 2 150 ARG 150 162 ?   ?   ?   B . n 
C 2 151 MET 151 163 ?   ?   ?   B . n 
C 2 152 CYS 152 164 ?   ?   ?   B . n 
C 2 153 SER 153 165 ?   ?   ?   B . n 
C 2 154 LEU 154 166 ?   ?   ?   B . n 
C 2 155 MET 155 167 ?   ?   ?   B . n 
C 2 156 GLN 156 168 ?   ?   ?   B . n 
C 2 157 GLY 157 169 ?   ?   ?   B . n 
C 2 158 SER 158 170 ?   ?   ?   B . n 
C 2 159 THR 159 171 ?   ?   ?   B . n 
C 2 160 LEU 160 172 ?   ?   ?   B . n 
C 2 161 PRO 161 173 ?   ?   ?   B . n 
C 2 162 ARG 162 174 ?   ?   ?   B . n 
C 2 163 ARG 163 175 ?   ?   ?   B . n 
C 2 164 SER 164 176 ?   ?   ?   B . n 
C 2 165 GLY 165 177 ?   ?   ?   B . n 
C 2 166 ALA 166 178 ?   ?   ?   B . n 
C 2 167 ALA 167 179 ?   ?   ?   B . n 
C 2 168 GLY 168 180 ?   ?   ?   B . n 
C 2 169 ALA 169 181 ?   ?   ?   B . n 
C 2 170 ALA 170 182 ?   ?   ?   B . n 
C 2 171 VAL 171 183 ?   ?   ?   B . n 
C 2 172 LYS 172 184 ?   ?   ?   B . n 
C 2 173 GLY 173 185 ?   ?   ?   B . n 
C 2 174 VAL 174 186 ?   ?   ?   B . n 
C 2 175 GLY 175 187 ?   ?   ?   B . n 
C 2 176 THR 176 188 ?   ?   ?   B . n 
C 2 177 MET 177 189 ?   ?   ?   B . n 
C 2 178 VAL 178 190 ?   ?   ?   B . n 
C 2 179 MET 179 191 ?   ?   ?   B . n 
C 2 180 GLU 180 192 ?   ?   ?   B . n 
C 2 181 LEU 181 193 ?   ?   ?   B . n 
C 2 182 ILE 182 194 ?   ?   ?   B . n 
C 2 183 ARG 183 195 ?   ?   ?   B . n 
C 2 184 MET 184 196 ?   ?   ?   B . n 
C 2 185 ILE 185 197 ?   ?   ?   B . n 
C 2 186 LYS 186 198 ?   ?   ?   B . n 
C 2 187 ARG 187 199 ?   ?   ?   B . n 
C 2 188 GLY 188 200 ?   ?   ?   B . n 
C 2 189 ILE 189 201 ?   ?   ?   B . n 
C 2 190 ASN 190 202 ?   ?   ?   B . n 
C 2 191 ASP 191 203 ?   ?   ?   B . n 
C 2 192 ARG 192 204 ?   ?   ?   B . n 
C 2 193 ASN 193 205 ?   ?   ?   B . n 
C 2 194 PHE 194 206 ?   ?   ?   B . n 
C 2 195 TRP 195 207 ?   ?   ?   B . n 
C 2 196 ARG 196 208 ?   ?   ?   B . n 
C 2 197 GLY 197 209 ?   ?   ?   B . n 
C 2 198 GLU 198 210 ?   ?   ?   B . n 
C 2 199 ASN 199 211 ?   ?   ?   B . n 
C 2 200 GLY 200 212 ?   ?   ?   B . n 
C 2 201 ARG 201 213 ?   ?   ?   B . n 
C 2 202 ARG 202 214 ?   ?   ?   B . n 
C 2 203 THR 203 215 ?   ?   ?   B . n 
C 2 204 ARG 204 216 ?   ?   ?   B . n 
C 2 205 ILE 205 217 ?   ?   ?   B . n 
C 2 206 ALA 206 218 ?   ?   ?   B . n 
C 2 207 TYR 207 219 ?   ?   ?   B . n 
C 2 208 GLU 208 220 ?   ?   ?   B . n 
C 2 209 ARG 209 221 ?   ?   ?   B . n 
C 2 210 MET 210 222 ?   ?   ?   B . n 
C 2 211 CYS 211 223 ?   ?   ?   B . n 
C 2 212 ASN 212 224 ?   ?   ?   B . n 
C 2 213 ILE 213 225 ?   ?   ?   B . n 
C 2 214 LEU 214 226 ?   ?   ?   B . n 
C 2 215 LYS 215 227 ?   ?   ?   B . n 
C 2 216 GLY 216 228 ?   ?   ?   B . n 
C 2 217 LYS 217 229 ?   ?   ?   B . n 
C 2 218 PHE 218 230 ?   ?   ?   B . n 
C 2 219 GLN 219 231 ?   ?   ?   B . n 
C 2 220 THR 220 232 ?   ?   ?   B . n 
C 2 221 ALA 221 233 ?   ?   ?   B . n 
C 2 222 ALA 222 234 ?   ?   ?   B . n 
C 2 223 GLN 223 235 ?   ?   ?   B . n 
C 2 224 ARG 224 236 ?   ?   ?   B . n 
C 2 225 THR 225 237 ?   ?   ?   B . n 
C 2 226 MET 226 238 ?   ?   ?   B . n 
C 2 227 VAL 227 239 ?   ?   ?   B . n 
C 2 228 ASP 228 240 ?   ?   ?   B . n 
C 2 229 GLN 229 241 ?   ?   ?   B . n 
C 2 230 VAL 230 242 ?   ?   ?   B . n 
C 2 231 ARG 231 243 ?   ?   ?   B . n 
C 2 232 GLU 232 244 ?   ?   ?   B . n 
C 2 233 SER 233 245 ?   ?   ?   B . n 
C 2 234 ARG 234 246 ?   ?   ?   B . n 
C 2 235 ASN 235 247 ?   ?   ?   B . n 
C 2 236 PRO 236 248 ?   ?   ?   B . n 
C 2 237 GLY 237 249 ?   ?   ?   B . n 
C 2 238 ASN 238 250 ?   ?   ?   B . n 
C 2 239 ALA 239 251 ?   ?   ?   B . n 
C 2 240 GLU 240 252 ?   ?   ?   B . n 
C 2 241 PHE 241 253 ?   ?   ?   B . n 
C 2 242 GLU 242 254 ?   ?   ?   B . n 
C 2 243 ASP 243 255 ?   ?   ?   B . n 
C 2 244 LEU 244 256 ?   ?   ?   B . n 
C 2 245 ILE 245 257 ?   ?   ?   B . n 
C 2 246 PHE 246 258 ?   ?   ?   B . n 
C 2 247 LEU 247 259 ?   ?   ?   B . n 
C 2 248 ALA 248 260 ?   ?   ?   B . n 
C 2 249 ARG 249 261 ?   ?   ?   B . n 
C 2 250 SER 250 262 ?   ?   ?   B . n 
C 2 251 ALA 251 263 ?   ?   ?   B . n 
C 2 252 LEU 252 264 ?   ?   ?   B . n 
C 2 253 ILE 253 265 ?   ?   ?   B . n 
C 2 254 LEU 254 266 ?   ?   ?   B . n 
C 2 255 ARG 255 267 ?   ?   ?   B . n 
C 2 256 GLY 256 268 ?   ?   ?   B . n 
C 2 257 SER 257 269 ?   ?   ?   B . n 
C 2 258 VAL 258 270 ?   ?   ?   B . n 
C 2 259 ALA 259 271 ?   ?   ?   B . n 
C 2 260 HIS 260 272 ?   ?   ?   B . n 
C 2 261 LYS 261 273 ?   ?   ?   B . n 
C 2 262 SER 262 274 ?   ?   ?   B . n 
C 2 263 CYS 263 275 ?   ?   ?   B . n 
C 2 264 LEU 264 276 ?   ?   ?   B . n 
C 2 265 PRO 265 277 ?   ?   ?   B . n 
C 2 266 ALA 266 278 ?   ?   ?   B . n 
C 2 267 CYS 267 279 ?   ?   ?   B . n 
C 2 268 VAL 268 280 ?   ?   ?   B . n 
C 2 269 TYR 269 281 ?   ?   ?   B . n 
C 2 270 GLY 270 282 ?   ?   ?   B . n 
C 2 271 SER 271 283 ?   ?   ?   B . n 
C 2 272 ALA 272 284 ?   ?   ?   B . n 
C 2 273 VAL 273 285 ?   ?   ?   B . n 
C 2 274 ALA 274 286 ?   ?   ?   B . n 
C 2 275 SER 275 287 ?   ?   ?   B . n 
C 2 276 GLY 276 288 ?   ?   ?   B . n 
C 2 277 TYR 277 289 ?   ?   ?   B . n 
C 2 278 ASP 278 290 ?   ?   ?   B . n 
C 2 279 PHE 279 291 ?   ?   ?   B . n 
C 2 280 GLU 280 292 ?   ?   ?   B . n 
C 2 281 ARG 281 293 ?   ?   ?   B . n 
C 2 282 GLU 282 294 ?   ?   ?   B . n 
C 2 283 GLY 283 295 ?   ?   ?   B . n 
C 2 284 TYR 284 296 ?   ?   ?   B . n 
C 2 285 SER 285 297 ?   ?   ?   B . n 
C 2 286 LEU 286 298 ?   ?   ?   B . n 
C 2 287 VAL 287 299 ?   ?   ?   B . n 
C 2 288 GLY 288 300 ?   ?   ?   B . n 
C 2 289 ILE 289 301 ?   ?   ?   B . n 
C 2 290 ASP 290 302 ?   ?   ?   B . n 
C 2 291 PRO 291 303 ?   ?   ?   B . n 
C 2 292 PHE 292 304 ?   ?   ?   B . n 
C 2 293 ARG 293 305 ?   ?   ?   B . n 
C 2 294 LEU 294 306 ?   ?   ?   B . n 
C 2 295 LEU 295 307 ?   ?   ?   B . n 
C 2 296 GLN 296 308 ?   ?   ?   B . n 
C 2 297 ASN 297 309 ?   ?   ?   B . n 
C 2 298 SER 298 310 ?   ?   ?   B . n 
C 2 299 GLN 299 311 ?   ?   ?   B . n 
C 2 300 VAL 300 312 ?   ?   ?   B . n 
C 2 301 TYR 301 313 ?   ?   ?   B . n 
C 2 302 SER 302 314 ?   ?   ?   B . n 
C 2 303 LEU 303 315 ?   ?   ?   B . n 
C 2 304 ILE 304 316 ?   ?   ?   B . n 
C 2 305 ARG 305 317 ?   ?   ?   B . n 
C 2 306 PRO 306 318 ?   ?   ?   B . n 
C 2 307 ASN 307 319 ?   ?   ?   B . n 
C 2 308 GLU 308 320 ?   ?   ?   B . n 
C 2 309 ASN 309 321 ?   ?   ?   B . n 
C 2 310 PRO 310 322 ?   ?   ?   B . n 
C 2 311 ALA 311 323 ?   ?   ?   B . n 
C 2 312 HIS 312 324 ?   ?   ?   B . n 
C 2 313 LYS 313 325 ?   ?   ?   B . n 
C 2 314 SER 314 326 ?   ?   ?   B . n 
C 2 315 GLN 315 327 ?   ?   ?   B . n 
C 2 316 LEU 316 328 ?   ?   ?   B . n 
C 2 317 VAL 317 329 ?   ?   ?   B . n 
C 2 318 TRP 318 330 ?   ?   ?   B . n 
C 2 319 MET 319 331 ?   ?   ?   B . n 
C 2 320 ALA 320 332 ?   ?   ?   B . n 
C 2 321 CYS 321 333 ?   ?   ?   B . n 
C 2 322 HIS 322 334 ?   ?   ?   B . n 
C 2 323 SER 323 335 ?   ?   ?   B . n 
C 2 324 ALA 324 336 ?   ?   ?   B . n 
C 2 325 ALA 325 337 ?   ?   ?   B . n 
C 2 326 PHE 326 338 ?   ?   ?   B . n 
C 2 327 GLU 327 339 ?   ?   ?   B . n 
C 2 328 ASP 328 340 ?   ?   ?   B . n 
C 2 329 LEU 329 341 ?   ?   ?   B . n 
C 2 330 ARG 330 342 ?   ?   ?   B . n 
C 2 331 VAL 331 343 ?   ?   ?   B . n 
C 2 332 SER 332 344 ?   ?   ?   B . n 
C 2 333 SER 333 345 ?   ?   ?   B . n 
C 2 334 PHE 334 346 ?   ?   ?   B . n 
C 2 335 ILE 335 347 ?   ?   ?   B . n 
C 2 336 ARG 336 348 ?   ?   ?   B . n 
C 2 337 GLY 337 349 ?   ?   ?   B . n 
C 2 338 THR 338 350 ?   ?   ?   B . n 
C 2 339 LYS 339 351 ?   ?   ?   B . n 
C 2 340 VAL 340 352 ?   ?   ?   B . n 
C 2 341 VAL 341 353 ?   ?   ?   B . n 
C 2 342 PRO 342 354 ?   ?   ?   B . n 
C 2 343 ARG 343 355 ?   ?   ?   B . n 
C 2 344 GLY 344 356 ?   ?   ?   B . n 
C 2 345 LYS 345 357 ?   ?   ?   B . n 
C 2 346 LEU 346 358 ?   ?   ?   B . n 
C 2 347 SER 347 359 ?   ?   ?   B . n 
C 2 348 THR 348 360 ?   ?   ?   B . n 
C 2 349 ARG 349 361 ?   ?   ?   B . n 
C 2 350 GLY 350 362 ?   ?   ?   B . n 
C 2 351 VAL 351 363 ?   ?   ?   B . n 
C 2 352 GLN 352 364 ?   ?   ?   B . n 
C 2 353 ILE 353 365 ?   ?   ?   B . n 
C 2 354 ALA 354 366 ?   ?   ?   B . n 
C 2 355 SER 355 367 ?   ?   ?   B . n 
C 2 356 ASN 356 368 ?   ?   ?   B . n 
C 2 357 GLU 357 369 ?   ?   ?   B . n 
C 2 358 ASN 358 370 ?   ?   ?   B . n 
C 2 359 MET 359 371 ?   ?   ?   B . n 
C 2 360 GLU 360 372 ?   ?   ?   B . n 
C 2 361 THR 361 373 ?   ?   ?   B . n 
C 2 362 MET 362 374 ?   ?   ?   B . n 
C 2 363 GLU 363 375 ?   ?   ?   B . n 
C 2 364 SER 364 376 ?   ?   ?   B . n 
C 2 365 SER 365 377 ?   ?   ?   B . n 
C 2 366 THR 366 378 ?   ?   ?   B . n 
C 2 367 LEU 367 379 ?   ?   ?   B . n 
C 2 368 GLU 368 380 ?   ?   ?   B . n 
C 2 369 LEU 369 381 ?   ?   ?   B . n 
C 2 370 ARG 370 382 ?   ?   ?   B . n 
C 2 371 SER 371 383 ?   ?   ?   B . n 
C 2 372 ARG 372 384 ?   ?   ?   B . n 
C 2 373 TYR 373 385 ?   ?   ?   B . n 
C 2 374 TRP 374 386 ?   ?   ?   B . n 
C 2 375 ALA 375 387 ?   ?   ?   B . n 
C 2 376 ILE 376 388 ?   ?   ?   B . n 
C 2 377 ARG 377 389 ?   ?   ?   B . n 
C 2 378 THR 378 390 ?   ?   ?   B . n 
C 2 379 ARG 379 391 ?   ?   ?   B . n 
C 2 380 SER 380 392 ?   ?   ?   B . n 
C 2 381 GLY 381 393 ?   ?   ?   B . n 
C 2 382 GLY 382 394 ?   ?   ?   B . n 
C 2 383 ASN 383 395 ?   ?   ?   B . n 
C 2 384 THR 384 396 ?   ?   ?   B . n 
C 2 385 ASN 385 397 ?   ?   ?   B . n 
C 2 386 GLN 386 398 ?   ?   ?   B . n 
C 2 387 GLN 387 399 ?   ?   ?   B . n 
C 2 388 ARG 388 400 ?   ?   ?   B . n 
C 2 389 ALA 389 401 ?   ?   ?   B . n 
C 2 390 SER 390 402 ?   ?   ?   B . n 
C 2 391 SER 391 403 403 SER SER B . n 
C 2 392 GLY 392 404 404 GLY GLY B . n 
C 2 393 GLN 393 405 405 GLN GLN B . n 
C 2 394 ILE 394 406 406 ILE ILE B . n 
C 2 395 SER 395 407 407 SER SER B . n 
C 2 396 ILE 396 408 408 ILE ILE B . n 
C 2 397 GLN 397 409 409 GLN GLN B . n 
C 2 398 PRO 398 410 410 PRO PRO B . n 
C 2 399 THR 399 411 411 THR THR B . n 
C 2 400 PHE 400 412 412 PHE PHE B . n 
C 2 401 SER 401 413 413 SER SER B . n 
C 2 402 VAL 402 414 414 VAL VAL B . n 
C 2 403 GLN 403 415 415 GLN GLN B . n 
C 2 404 ARG 404 416 416 ARG ARG B . n 
C 2 405 ASN 405 417 417 ASN ASN B . n 
C 2 406 LEU 406 418 418 LEU LEU B . n 
C 2 407 PRO 407 419 419 PRO PRO B . n 
C 2 408 PHE 408 420 420 PHE PHE B . n 
C 2 409 ASP 409 421 421 ASP ASP B . n 
C 2 410 ARG 410 422 422 ARG ARG B . n 
C 2 411 PRO 411 423 423 PRO PRO B . n 
C 2 412 THR 412 424 424 THR THR B . n 
C 2 413 ILE 413 425 425 ILE ILE B . n 
C 2 414 MET 414 426 426 MET MET B . n 
C 2 415 ALA 415 427 427 ALA ALA B . n 
C 2 416 ALA 416 428 428 ALA ALA B . n 
C 2 417 PHE 417 429 429 PHE PHE B . n 
C 2 418 THR 418 430 430 THR THR B . n 
C 2 419 GLY 419 431 ?   ?   ?   B . n 
C 2 420 ASN 420 432 ?   ?   ?   B . n 
C 2 421 THR 421 433 ?   ?   ?   B . n 
C 2 422 GLU 422 434 ?   ?   ?   B . n 
C 2 423 GLY 423 435 ?   ?   ?   B . n 
C 2 424 ARG 424 436 ?   ?   ?   B . n 
C 2 425 THR 425 437 ?   ?   ?   B . n 
C 2 426 SER 426 438 ?   ?   ?   B . n 
C 2 427 ASP 427 439 ?   ?   ?   B . n 
C 2 428 MET 428 440 ?   ?   ?   B . n 
C 2 429 ARG 429 441 ?   ?   ?   B . n 
C 2 430 THR 430 442 ?   ?   ?   B . n 
C 2 431 GLU 431 443 ?   ?   ?   B . n 
C 2 432 ILE 432 444 ?   ?   ?   B . n 
C 2 433 ILE 433 445 ?   ?   ?   B . n 
C 2 434 ARG 434 446 ?   ?   ?   B . n 
C 2 435 LEU 435 447 ?   ?   ?   B . n 
C 2 436 MET 436 448 ?   ?   ?   B . n 
C 2 437 GLU 437 449 ?   ?   ?   B . n 
C 2 438 SER 438 450 ?   ?   ?   B . n 
C 2 439 ALA 439 451 ?   ?   ?   B . n 
C 2 440 ARG 440 452 ?   ?   ?   B . n 
C 2 441 PRO 441 453 ?   ?   ?   B . n 
C 2 442 GLU 442 454 ?   ?   ?   B . n 
C 2 443 ASP 443 455 ?   ?   ?   B . n 
C 2 444 VAL 444 456 ?   ?   ?   B . n 
C 2 445 SER 445 457 ?   ?   ?   B . n 
C 2 446 PHE 446 458 ?   ?   ?   B . n 
C 2 447 GLN 447 459 ?   ?   ?   B . n 
C 2 448 GLY 448 460 ?   ?   ?   B . n 
C 2 449 ARG 449 461 ?   ?   ?   B . n 
C 2 450 GLY 450 462 ?   ?   ?   B . n 
C 2 451 VAL 451 463 ?   ?   ?   B . n 
C 2 452 PHE 452 464 ?   ?   ?   B . n 
C 2 453 GLU 453 465 ?   ?   ?   B . n 
C 2 454 LEU 454 466 ?   ?   ?   B . n 
C 2 455 SER 455 467 ?   ?   ?   B . n 
C 2 456 ASP 456 468 ?   ?   ?   B . n 
C 2 457 GLU 457 469 ?   ?   ?   B . n 
C 2 458 LYS 458 470 ?   ?   ?   B . n 
C 2 459 ALA 459 471 ?   ?   ?   B . n 
C 2 460 THR 460 472 ?   ?   ?   B . n 
C 2 461 SER 461 473 ?   ?   ?   B . n 
C 2 462 PRO 462 474 ?   ?   ?   B . n 
C 2 463 ILE 463 475 ?   ?   ?   B . n 
C 2 464 VAL 464 476 ?   ?   ?   B . n 
C 2 465 PRO 465 477 ?   ?   ?   B . n 
C 2 466 SER 466 478 ?   ?   ?   B . n 
C 2 467 PHE 467 479 ?   ?   ?   B . n 
C 2 468 ASP 468 480 ?   ?   ?   B . n 
C 2 469 MET 469 481 ?   ?   ?   B . n 
C 2 470 SER 470 482 ?   ?   ?   B . n 
C 2 471 ASN 471 483 ?   ?   ?   B . n 
C 2 472 GLU 472 484 ?   ?   ?   B . n 
C 2 473 GLY 473 485 ?   ?   ?   B . n 
C 2 474 SER 474 486 ?   ?   ?   B . n 
C 2 475 TYR 475 487 ?   ?   ?   B . n 
C 2 476 PHE 476 488 ?   ?   ?   B . n 
C 2 477 PHE 477 489 ?   ?   ?   B . n 
C 2 478 GLY 478 490 ?   ?   ?   B . n 
C 2 479 ASP 479 491 ?   ?   ?   B . n 
C 2 480 ASN 480 492 ?   ?   ?   B . n 
C 2 481 ALA 481 493 ?   ?   ?   B . n 
C 2 482 GLU 482 494 ?   ?   ?   B . n 
C 2 483 GLU 483 495 ?   ?   ?   B . n 
C 2 484 TYR 484 496 ?   ?   ?   B . n 
C 2 485 ASP 485 497 ?   ?   ?   B . n 
C 2 486 ASN 486 498 ?   ?   ?   B . n 
C 2 487 LEU 487 499 ?   ?   ?   B . n 
C 2 488 GLU 488 500 ?   ?   ?   B . n 
C 2 489 HIS 489 501 ?   ?   ?   B . n 
C 2 490 HIS 490 502 ?   ?   ?   B . n 
C 2 491 HIS 491 503 ?   ?   ?   B . n 
C 2 492 HIS 492 504 ?   ?   ?   B . n 
C 2 493 HIS 493 505 ?   ?   ?   B . n 
C 2 494 HIS 494 506 ?   ?   ?   B . n 
D 2 1   HIS 1   13  ?   ?   ?   A . n 
D 2 2   MET 2   14  ?   ?   ?   A . n 
D 2 3   THR 3   15  ?   ?   ?   A . n 
D 2 4   ASP 4   16  ?   ?   ?   A . n 
D 2 5   GLY 5   17  ?   ?   ?   A . n 
D 2 6   GLU 6   18  18  GLU GLU A . n 
D 2 7   ARG 7   19  19  ARG ARG A . n 
D 2 8   GLN 8   20  20  GLN GLN A . n 
D 2 9   ASN 9   21  21  ASN ASN A . n 
D 2 10  ALA 10  22  22  ALA ALA A . n 
D 2 11  THR 11  23  23  THR THR A . n 
D 2 12  GLU 12  24  24  GLU GLU A . n 
D 2 13  ILE 13  25  25  ILE ILE A . n 
D 2 14  ARG 14  26  26  ARG ARG A . n 
D 2 15  ALA 15  27  27  ALA ALA A . n 
D 2 16  SER 16  28  28  SER SER A . n 
D 2 17  VAL 17  29  29  VAL VAL A . n 
D 2 18  GLY 18  30  30  GLY GLY A . n 
D 2 19  LYS 19  31  31  LYS LYS A . n 
D 2 20  MET 20  32  32  MET MET A . n 
D 2 21  ILE 21  33  33  ILE ILE A . n 
D 2 22  ASP 22  34  34  ASP ASP A . n 
D 2 23  GLY 23  35  35  GLY GLY A . n 
D 2 24  ILE 24  36  36  ILE ILE A . n 
D 2 25  GLY 25  37  37  GLY GLY A . n 
D 2 26  ARG 26  38  38  ARG ARG A . n 
D 2 27  PHE 27  39  39  PHE PHE A . n 
D 2 28  TYR 28  40  40  TYR TYR A . n 
D 2 29  ILE 29  41  41  ILE ILE A . n 
D 2 30  GLN 30  42  42  GLN GLN A . n 
D 2 31  MET 31  43  43  MET MET A . n 
D 2 32  CYS 32  44  44  CYS CYS A . n 
D 2 33  THR 33  45  45  THR THR A . n 
D 2 34  GLU 34  46  46  GLU GLU A . n 
D 2 35  LEU 35  47  47  LEU LEU A . n 
D 2 36  LYS 36  48  48  LYS LYS A . n 
D 2 37  LEU 37  49  49  LEU LEU A . n 
D 2 38  SER 38  50  50  SER SER A . n 
D 2 39  ASP 39  51  51  ASP ASP A . n 
D 2 40  TYR 40  52  52  TYR TYR A . n 
D 2 41  GLU 41  53  53  GLU GLU A . n 
D 2 42  GLY 42  54  54  GLY GLY A . n 
D 2 43  ARG 43  55  55  ARG ARG A . n 
D 2 44  LEU 44  56  56  LEU LEU A . n 
D 2 45  ILE 45  57  57  ILE ILE A . n 
D 2 46  GLN 46  58  58  GLN GLN A . n 
D 2 47  ASN 47  59  59  ASN ASN A . n 
D 2 48  SER 48  60  60  SER SER A . n 
D 2 49  LEU 49  61  61  LEU LEU A . n 
D 2 50  THR 50  62  62  THR THR A . n 
D 2 51  ILE 51  63  63  ILE ILE A . n 
D 2 52  GLU 52  64  64  GLU GLU A . n 
D 2 53  ARG 53  65  65  ARG ARG A . n 
D 2 54  MET 54  66  66  MET MET A . n 
D 2 55  VAL 55  67  67  VAL VAL A . n 
D 2 56  LEU 56  68  68  LEU LEU A . n 
D 2 57  SER 57  69  69  SER SER A . n 
D 2 58  ALA 58  70  70  ALA ALA A . n 
D 2 59  PHE 59  71  71  PHE PHE A . n 
D 2 60  ASP 60  72  72  ASP ASP A . n 
D 2 61  GLU 61  73  73  GLU GLU A . n 
D 2 62  ARG 62  74  74  ARG ARG A . n 
D 2 63  ARG 63  75  75  ARG ARG A . n 
D 2 64  ASN 64  76  76  ASN ASN A . n 
D 2 65  LYS 65  77  77  LYS LYS A . n 
D 2 66  TYR 66  78  78  TYR TYR A . n 
D 2 67  LEU 67  79  79  LEU LEU A . n 
D 2 68  GLU 68  80  80  GLU GLU A . n 
D 2 69  GLU 69  81  81  GLU GLU A . n 
D 2 70  HIS 70  82  82  HIS HIS A . n 
D 2 71  PRO 71  83  83  PRO PRO A . n 
D 2 72  SER 72  84  84  SER SER A . n 
D 2 73  ALA 73  85  85  ALA ALA A . n 
D 2 74  GLY 74  86  86  GLY GLY A . n 
D 2 75  LYS 75  87  87  LYS LYS A . n 
D 2 76  ASP 76  88  88  ASP ASP A . n 
D 2 77  PRO 77  89  89  PRO PRO A . n 
D 2 78  LYS 78  90  90  LYS LYS A . n 
D 2 79  LYS 79  91  91  LYS LYS A . n 
D 2 80  THR 80  92  92  THR THR A . n 
D 2 81  GLY 81  93  93  GLY GLY A . n 
D 2 82  GLY 82  94  94  GLY GLY A . n 
D 2 83  PRO 83  95  95  PRO PRO A . n 
D 2 84  ILE 84  96  96  ILE ILE A . n 
D 2 85  TYR 85  97  97  TYR TYR A . n 
D 2 86  ARG 86  98  98  ARG ARG A . n 
D 2 87  ARG 87  99  99  ARG ARG A . n 
D 2 88  VAL 88  100 100 VAL VAL A . n 
D 2 89  ASP 89  101 101 ASP ASP A . n 
D 2 90  GLY 90  102 102 GLY GLY A . n 
D 2 91  LYS 91  103 103 LYS LYS A . n 
D 2 92  TRP 92  104 104 TRP TRP A . n 
D 2 93  ARG 93  105 105 ARG ARG A . n 
D 2 94  ARG 94  106 106 ARG ARG A . n 
D 2 95  GLU 95  107 107 GLU GLU A . n 
D 2 96  LEU 96  108 108 LEU LEU A . n 
D 2 97  ILE 97  109 109 ILE ILE A . n 
D 2 98  LEU 98  110 110 LEU LEU A . n 
D 2 99  TYR 99  111 111 TYR TYR A . n 
D 2 100 ASP 100 112 112 ASP ASP A . n 
D 2 101 LYS 101 113 113 LYS LYS A . n 
D 2 102 GLU 102 114 114 GLU GLU A . n 
D 2 103 GLU 103 115 115 GLU GLU A . n 
D 2 104 ILE 104 116 116 ILE ILE A . n 
D 2 105 ARG 105 117 117 ARG ARG A . n 
D 2 106 ARG 106 118 118 ARG ARG A . n 
D 2 107 ILE 107 119 119 ILE ILE A . n 
D 2 108 TRP 108 120 120 TRP TRP A . n 
D 2 109 ARG 109 121 121 ARG ARG A . n 
D 2 110 GLN 110 122 122 GLN GLN A . n 
D 2 111 ALA 111 123 123 ALA ALA A . n 
D 2 112 ASN 112 124 124 ASN ASN A . n 
D 2 113 ASN 113 125 125 ASN ASN A . n 
D 2 114 GLY 114 126 126 GLY GLY A . n 
D 2 115 ASP 115 127 127 ASP ASP A . n 
D 2 116 ASP 116 128 128 ASP ASP A . n 
D 2 117 ALA 117 129 129 ALA ALA A . n 
D 2 118 THR 118 130 130 THR THR A . n 
D 2 119 ALA 119 131 131 ALA ALA A . n 
D 2 120 GLY 120 132 132 GLY GLY A . n 
D 2 121 LEU 121 133 133 LEU LEU A . n 
D 2 122 THR 122 134 134 THR THR A . n 
D 2 123 HIS 123 135 135 HIS HIS A . n 
D 2 124 MET 124 136 136 MET MET A . n 
D 2 125 MET 125 137 137 MET MET A . n 
D 2 126 ILE 126 138 138 ILE ILE A . n 
D 2 127 TRP 127 139 139 TRP TRP A . n 
D 2 128 HIS 128 140 140 HIS HIS A . n 
D 2 129 SER 129 141 141 SER SER A . n 
D 2 130 ASN 130 142 142 ASN ASN A . n 
D 2 131 LEU 131 143 143 LEU LEU A . n 
D 2 132 ASN 132 144 144 ASN ASN A . n 
D 2 133 ASP 133 145 145 ASP ASP A . n 
D 2 134 ALA 134 146 146 ALA ALA A . n 
D 2 135 THR 135 147 147 THR THR A . n 
D 2 136 TYR 136 148 148 TYR TYR A . n 
D 2 137 GLN 137 149 149 GLN GLN A . n 
D 2 138 ARG 138 150 150 ARG ARG A . n 
D 2 139 THR 139 151 151 THR THR A . n 
D 2 140 ARG 140 152 152 ARG ARG A . n 
D 2 141 ALA 141 153 153 ALA ALA A . n 
D 2 142 LEU 142 154 154 LEU LEU A . n 
D 2 143 VAL 143 155 155 VAL VAL A . n 
D 2 144 ARG 144 156 156 ARG ARG A . n 
D 2 145 THR 145 157 157 THR THR A . n 
D 2 146 GLY 146 158 158 GLY GLY A . n 
D 2 147 MET 147 159 159 MET MET A . n 
D 2 148 ASP 148 160 160 ASP ASP A . n 
D 2 149 PRO 149 161 161 PRO PRO A . n 
D 2 150 ARG 150 162 162 ARG ARG A . n 
D 2 151 MET 151 163 163 MET MET A . n 
D 2 152 CYS 152 164 164 CYS CYS A . n 
D 2 153 SER 153 165 165 SER SER A . n 
D 2 154 LEU 154 166 166 LEU LEU A . n 
D 2 155 MET 155 167 167 MET MET A . n 
D 2 156 GLN 156 168 168 GLN GLN A . n 
D 2 157 GLY 157 169 169 GLY GLY A . n 
D 2 158 SER 158 170 170 SER SER A . n 
D 2 159 THR 159 171 171 THR THR A . n 
D 2 160 LEU 160 172 172 LEU LEU A . n 
D 2 161 PRO 161 173 173 PRO PRO A . n 
D 2 162 ARG 162 174 174 ARG ARG A . n 
D 2 163 ARG 163 175 175 ARG ARG A . n 
D 2 164 SER 164 176 176 SER SER A . n 
D 2 165 GLY 165 177 177 GLY GLY A . n 
D 2 166 ALA 166 178 178 ALA ALA A . n 
D 2 167 ALA 167 179 179 ALA ALA A . n 
D 2 168 GLY 168 180 180 GLY GLY A . n 
D 2 169 ALA 169 181 181 ALA ALA A . n 
D 2 170 ALA 170 182 182 ALA ALA A . n 
D 2 171 VAL 171 183 183 VAL VAL A . n 
D 2 172 LYS 172 184 184 LYS LYS A . n 
D 2 173 GLY 173 185 185 GLY GLY A . n 
D 2 174 VAL 174 186 186 VAL VAL A . n 
D 2 175 GLY 175 187 187 GLY GLY A . n 
D 2 176 THR 176 188 188 THR THR A . n 
D 2 177 MET 177 189 189 MET MET A . n 
D 2 178 VAL 178 190 190 VAL VAL A . n 
D 2 179 MET 179 191 191 MET MET A . n 
D 2 180 GLU 180 192 192 GLU GLU A . n 
D 2 181 LEU 181 193 193 LEU LEU A . n 
D 2 182 ILE 182 194 194 ILE ILE A . n 
D 2 183 ARG 183 195 195 ARG ARG A . n 
D 2 184 MET 184 196 196 MET MET A . n 
D 2 185 ILE 185 197 197 ILE ILE A . n 
D 2 186 LYS 186 198 198 LYS LYS A . n 
D 2 187 ARG 187 199 199 ARG ARG A . n 
D 2 188 GLY 188 200 200 GLY GLY A . n 
D 2 189 ILE 189 201 201 ILE ILE A . n 
D 2 190 ASN 190 202 202 ASN ASN A . n 
D 2 191 ASP 191 203 203 ASP ASP A . n 
D 2 192 ARG 192 204 204 ARG ARG A . n 
D 2 193 ASN 193 205 205 ASN ASN A . n 
D 2 194 PHE 194 206 206 PHE PHE A . n 
D 2 195 TRP 195 207 207 TRP TRP A . n 
D 2 196 ARG 196 208 208 ARG ARG A . n 
D 2 197 GLY 197 209 209 GLY GLY A . n 
D 2 198 GLU 198 210 210 GLU GLU A . n 
D 2 199 ASN 199 211 211 ASN ASN A . n 
D 2 200 GLY 200 212 212 GLY GLY A . n 
D 2 201 ARG 201 213 213 ARG ARG A . n 
D 2 202 ARG 202 214 214 ARG ARG A . n 
D 2 203 THR 203 215 215 THR THR A . n 
D 2 204 ARG 204 216 216 ARG ARG A . n 
D 2 205 ILE 205 217 217 ILE ILE A . n 
D 2 206 ALA 206 218 218 ALA ALA A . n 
D 2 207 TYR 207 219 219 TYR TYR A . n 
D 2 208 GLU 208 220 220 GLU GLU A . n 
D 2 209 ARG 209 221 221 ARG ARG A . n 
D 2 210 MET 210 222 222 MET MET A . n 
D 2 211 CYS 211 223 223 CYS CYS A . n 
D 2 212 ASN 212 224 224 ASN ASN A . n 
D 2 213 ILE 213 225 225 ILE ILE A . n 
D 2 214 LEU 214 226 226 LEU LEU A . n 
D 2 215 LYS 215 227 227 LYS LYS A . n 
D 2 216 GLY 216 228 228 GLY GLY A . n 
D 2 217 LYS 217 229 229 LYS LYS A . n 
D 2 218 PHE 218 230 230 PHE PHE A . n 
D 2 219 GLN 219 231 231 GLN GLN A . n 
D 2 220 THR 220 232 232 THR THR A . n 
D 2 221 ALA 221 233 233 ALA ALA A . n 
D 2 222 ALA 222 234 234 ALA ALA A . n 
D 2 223 GLN 223 235 235 GLN GLN A . n 
D 2 224 ARG 224 236 236 ARG ARG A . n 
D 2 225 THR 225 237 237 THR THR A . n 
D 2 226 MET 226 238 238 MET MET A . n 
D 2 227 VAL 227 239 239 VAL VAL A . n 
D 2 228 ASP 228 240 240 ASP ASP A . n 
D 2 229 GLN 229 241 241 GLN GLN A . n 
D 2 230 VAL 230 242 242 VAL VAL A . n 
D 2 231 ARG 231 243 243 ARG ARG A . n 
D 2 232 GLU 232 244 244 GLU GLU A . n 
D 2 233 SER 233 245 245 SER SER A . n 
D 2 234 ARG 234 246 246 ARG ARG A . n 
D 2 235 ASN 235 247 247 ASN ASN A . n 
D 2 236 PRO 236 248 248 PRO PRO A . n 
D 2 237 GLY 237 249 249 GLY GLY A . n 
D 2 238 ASN 238 250 250 ASN ASN A . n 
D 2 239 ALA 239 251 251 ALA ALA A . n 
D 2 240 GLU 240 252 252 GLU GLU A . n 
D 2 241 PHE 241 253 253 PHE PHE A . n 
D 2 242 GLU 242 254 254 GLU GLU A . n 
D 2 243 ASP 243 255 255 ASP ASP A . n 
D 2 244 LEU 244 256 256 LEU LEU A . n 
D 2 245 ILE 245 257 257 ILE ILE A . n 
D 2 246 PHE 246 258 258 PHE PHE A . n 
D 2 247 LEU 247 259 259 LEU LEU A . n 
D 2 248 ALA 248 260 260 ALA ALA A . n 
D 2 249 ARG 249 261 261 ARG ARG A . n 
D 2 250 SER 250 262 262 SER SER A . n 
D 2 251 ALA 251 263 263 ALA ALA A . n 
D 2 252 LEU 252 264 264 LEU LEU A . n 
D 2 253 ILE 253 265 265 ILE ILE A . n 
D 2 254 LEU 254 266 266 LEU LEU A . n 
D 2 255 ARG 255 267 267 ARG ARG A . n 
D 2 256 GLY 256 268 268 GLY GLY A . n 
D 2 257 SER 257 269 269 SER SER A . n 
D 2 258 VAL 258 270 270 VAL VAL A . n 
D 2 259 ALA 259 271 271 ALA ALA A . n 
D 2 260 HIS 260 272 272 HIS HIS A . n 
D 2 261 LYS 261 273 273 LYS LYS A . n 
D 2 262 SER 262 274 274 SER SER A . n 
D 2 263 CYS 263 275 275 CYS CYS A . n 
D 2 264 LEU 264 276 276 LEU LEU A . n 
D 2 265 PRO 265 277 277 PRO PRO A . n 
D 2 266 ALA 266 278 278 ALA ALA A . n 
D 2 267 CYS 267 279 279 CYS CYS A . n 
D 2 268 VAL 268 280 280 VAL VAL A . n 
D 2 269 TYR 269 281 281 TYR TYR A . n 
D 2 270 GLY 270 282 282 GLY GLY A . n 
D 2 271 SER 271 283 283 SER SER A . n 
D 2 272 ALA 272 284 284 ALA ALA A . n 
D 2 273 VAL 273 285 285 VAL VAL A . n 
D 2 274 ALA 274 286 286 ALA ALA A . n 
D 2 275 SER 275 287 287 SER SER A . n 
D 2 276 GLY 276 288 288 GLY GLY A . n 
D 2 277 TYR 277 289 289 TYR TYR A . n 
D 2 278 ASP 278 290 290 ASP ASP A . n 
D 2 279 PHE 279 291 291 PHE PHE A . n 
D 2 280 GLU 280 292 292 GLU GLU A . n 
D 2 281 ARG 281 293 293 ARG ARG A . n 
D 2 282 GLU 282 294 294 GLU GLU A . n 
D 2 283 GLY 283 295 295 GLY GLY A . n 
D 2 284 TYR 284 296 296 TYR TYR A . n 
D 2 285 SER 285 297 297 SER SER A . n 
D 2 286 LEU 286 298 298 LEU LEU A . n 
D 2 287 VAL 287 299 299 VAL VAL A . n 
D 2 288 GLY 288 300 300 GLY GLY A . n 
D 2 289 ILE 289 301 301 ILE ILE A . n 
D 2 290 ASP 290 302 302 ASP ASP A . n 
D 2 291 PRO 291 303 303 PRO PRO A . n 
D 2 292 PHE 292 304 304 PHE PHE A . n 
D 2 293 ARG 293 305 305 ARG ARG A . n 
D 2 294 LEU 294 306 306 LEU LEU A . n 
D 2 295 LEU 295 307 307 LEU LEU A . n 
D 2 296 GLN 296 308 308 GLN GLN A . n 
D 2 297 ASN 297 309 309 ASN ASN A . n 
D 2 298 SER 298 310 310 SER SER A . n 
D 2 299 GLN 299 311 311 GLN GLN A . n 
D 2 300 VAL 300 312 312 VAL VAL A . n 
D 2 301 TYR 301 313 313 TYR TYR A . n 
D 2 302 SER 302 314 314 SER SER A . n 
D 2 303 LEU 303 315 315 LEU LEU A . n 
D 2 304 ILE 304 316 316 ILE ILE A . n 
D 2 305 ARG 305 317 317 ARG ARG A . n 
D 2 306 PRO 306 318 318 PRO PRO A . n 
D 2 307 ASN 307 319 319 ASN ASN A . n 
D 2 308 GLU 308 320 320 GLU GLU A . n 
D 2 309 ASN 309 321 321 ASN ASN A . n 
D 2 310 PRO 310 322 322 PRO PRO A . n 
D 2 311 ALA 311 323 323 ALA ALA A . n 
D 2 312 HIS 312 324 324 HIS HIS A . n 
D 2 313 LYS 313 325 325 LYS LYS A . n 
D 2 314 SER 314 326 326 SER SER A . n 
D 2 315 GLN 315 327 327 GLN GLN A . n 
D 2 316 LEU 316 328 328 LEU LEU A . n 
D 2 317 VAL 317 329 329 VAL VAL A . n 
D 2 318 TRP 318 330 330 TRP TRP A . n 
D 2 319 MET 319 331 331 MET MET A . n 
D 2 320 ALA 320 332 332 ALA ALA A . n 
D 2 321 CYS 321 333 333 CYS CYS A . n 
D 2 322 HIS 322 334 334 HIS HIS A . n 
D 2 323 SER 323 335 335 SER SER A . n 
D 2 324 ALA 324 336 336 ALA ALA A . n 
D 2 325 ALA 325 337 337 ALA ALA A . n 
D 2 326 PHE 326 338 338 PHE PHE A . n 
D 2 327 GLU 327 339 339 GLU GLU A . n 
D 2 328 ASP 328 340 340 ASP ASP A . n 
D 2 329 LEU 329 341 341 LEU LEU A . n 
D 2 330 ARG 330 342 342 ARG ARG A . n 
D 2 331 VAL 331 343 343 VAL VAL A . n 
D 2 332 SER 332 344 344 SER SER A . n 
D 2 333 SER 333 345 345 SER SER A . n 
D 2 334 PHE 334 346 346 PHE PHE A . n 
D 2 335 ILE 335 347 347 ILE ILE A . n 
D 2 336 ARG 336 348 348 ARG ARG A . n 
D 2 337 GLY 337 349 349 GLY GLY A . n 
D 2 338 THR 338 350 350 THR THR A . n 
D 2 339 LYS 339 351 351 LYS LYS A . n 
D 2 340 VAL 340 352 352 VAL VAL A . n 
D 2 341 VAL 341 353 353 VAL VAL A . n 
D 2 342 PRO 342 354 354 PRO PRO A . n 
D 2 343 ARG 343 355 355 ARG ARG A . n 
D 2 344 GLY 344 356 356 GLY GLY A . n 
D 2 345 LYS 345 357 357 LYS LYS A . n 
D 2 346 LEU 346 358 358 LEU LEU A . n 
D 2 347 SER 347 359 359 SER SER A . n 
D 2 348 THR 348 360 360 THR THR A . n 
D 2 349 ARG 349 361 361 ARG ARG A . n 
D 2 350 GLY 350 362 362 GLY GLY A . n 
D 2 351 VAL 351 363 363 VAL VAL A . n 
D 2 352 GLN 352 364 364 GLN GLN A . n 
D 2 353 ILE 353 365 365 ILE ILE A . n 
D 2 354 ALA 354 366 366 ALA ALA A . n 
D 2 355 SER 355 367 367 SER SER A . n 
D 2 356 ASN 356 368 368 ASN ASN A . n 
D 2 357 GLU 357 369 369 GLU GLU A . n 
D 2 358 ASN 358 370 370 ASN ASN A . n 
D 2 359 MET 359 371 371 MET MET A . n 
D 2 360 GLU 360 372 372 GLU GLU A . n 
D 2 361 THR 361 373 373 THR THR A . n 
D 2 362 MET 362 374 374 MET MET A . n 
D 2 363 GLU 363 375 375 GLU GLU A . n 
D 2 364 SER 364 376 376 SER SER A . n 
D 2 365 SER 365 377 377 SER SER A . n 
D 2 366 THR 366 378 378 THR THR A . n 
D 2 367 LEU 367 379 379 LEU LEU A . n 
D 2 368 GLU 368 380 380 GLU GLU A . n 
D 2 369 LEU 369 381 381 LEU LEU A . n 
D 2 370 ARG 370 382 382 ARG ARG A . n 
D 2 371 SER 371 383 383 SER SER A . n 
D 2 372 ARG 372 384 384 ARG ARG A . n 
D 2 373 TYR 373 385 385 TYR TYR A . n 
D 2 374 TRP 374 386 386 TRP TRP A . n 
D 2 375 ALA 375 387 387 ALA ALA A . n 
D 2 376 ILE 376 388 388 ILE ILE A . n 
D 2 377 ARG 377 389 389 ARG ARG A . n 
D 2 378 THR 378 390 390 THR THR A . n 
D 2 379 ARG 379 391 391 ARG ARG A . n 
D 2 380 SER 380 392 392 SER SER A . n 
D 2 381 GLY 381 393 393 GLY GLY A . n 
D 2 382 GLY 382 394 394 GLY GLY A . n 
D 2 383 ASN 383 395 395 ASN ASN A . n 
D 2 384 THR 384 396 396 THR THR A . n 
D 2 385 ASN 385 397 397 ASN ASN A . n 
D 2 386 GLN 386 398 ?   ?   ?   A . n 
D 2 387 GLN 387 399 ?   ?   ?   A . n 
D 2 388 ARG 388 400 ?   ?   ?   A . n 
D 2 389 ALA 389 401 ?   ?   ?   A . n 
D 2 390 SER 390 402 ?   ?   ?   A . n 
D 2 391 SER 391 403 ?   ?   ?   A . n 
D 2 392 GLY 392 404 ?   ?   ?   A . n 
D 2 393 GLN 393 405 ?   ?   ?   A . n 
D 2 394 ILE 394 406 ?   ?   ?   A . n 
D 2 395 SER 395 407 ?   ?   ?   A . n 
D 2 396 ILE 396 408 ?   ?   ?   A . n 
D 2 397 GLN 397 409 ?   ?   ?   A . n 
D 2 398 PRO 398 410 ?   ?   ?   A . n 
D 2 399 THR 399 411 ?   ?   ?   A . n 
D 2 400 PHE 400 412 ?   ?   ?   A . n 
D 2 401 SER 401 413 ?   ?   ?   A . n 
D 2 402 VAL 402 414 ?   ?   ?   A . n 
D 2 403 GLN 403 415 ?   ?   ?   A . n 
D 2 404 ARG 404 416 ?   ?   ?   A . n 
D 2 405 ASN 405 417 ?   ?   ?   A . n 
D 2 406 LEU 406 418 ?   ?   ?   A . n 
D 2 407 PRO 407 419 ?   ?   ?   A . n 
D 2 408 PHE 408 420 ?   ?   ?   A . n 
D 2 409 ASP 409 421 ?   ?   ?   A . n 
D 2 410 ARG 410 422 ?   ?   ?   A . n 
D 2 411 PRO 411 423 ?   ?   ?   A . n 
D 2 412 THR 412 424 ?   ?   ?   A . n 
D 2 413 ILE 413 425 ?   ?   ?   A . n 
D 2 414 MET 414 426 ?   ?   ?   A . n 
D 2 415 ALA 415 427 ?   ?   ?   A . n 
D 2 416 ALA 416 428 ?   ?   ?   A . n 
D 2 417 PHE 417 429 ?   ?   ?   A . n 
D 2 418 THR 418 430 ?   ?   ?   A . n 
D 2 419 GLY 419 431 ?   ?   ?   A . n 
D 2 420 ASN 420 432 ?   ?   ?   A . n 
D 2 421 THR 421 433 ?   ?   ?   A . n 
D 2 422 GLU 422 434 ?   ?   ?   A . n 
D 2 423 GLY 423 435 ?   ?   ?   A . n 
D 2 424 ARG 424 436 ?   ?   ?   A . n 
D 2 425 THR 425 437 437 THR THR A . n 
D 2 426 SER 426 438 438 SER SER A . n 
D 2 427 ASP 427 439 439 ASP ASP A . n 
D 2 428 MET 428 440 440 MET MET A . n 
D 2 429 ARG 429 441 441 ARG ARG A . n 
D 2 430 THR 430 442 442 THR THR A . n 
D 2 431 GLU 431 443 443 GLU GLU A . n 
D 2 432 ILE 432 444 444 ILE ILE A . n 
D 2 433 ILE 433 445 445 ILE ILE A . n 
D 2 434 ARG 434 446 446 ARG ARG A . n 
D 2 435 LEU 435 447 447 LEU LEU A . n 
D 2 436 MET 436 448 448 MET MET A . n 
D 2 437 GLU 437 449 449 GLU GLU A . n 
D 2 438 SER 438 450 450 SER SER A . n 
D 2 439 ALA 439 451 451 ALA ALA A . n 
D 2 440 ARG 440 452 452 ARG ARG A . n 
D 2 441 PRO 441 453 453 PRO PRO A . n 
D 2 442 GLU 442 454 454 GLU GLU A . n 
D 2 443 ASP 443 455 455 ASP ASP A . n 
D 2 444 VAL 444 456 456 VAL VAL A . n 
D 2 445 SER 445 457 457 SER SER A . n 
D 2 446 PHE 446 458 458 PHE PHE A . n 
D 2 447 GLN 447 459 459 GLN GLN A . n 
D 2 448 GLY 448 460 460 GLY GLY A . n 
D 2 449 ARG 449 461 461 ARG ARG A . n 
D 2 450 GLY 450 462 462 GLY GLY A . n 
D 2 451 VAL 451 463 463 VAL VAL A . n 
D 2 452 PHE 452 464 464 PHE PHE A . n 
D 2 453 GLU 453 465 465 GLU GLU A . n 
D 2 454 LEU 454 466 466 LEU LEU A . n 
D 2 455 SER 455 467 467 SER SER A . n 
D 2 456 ASP 456 468 468 ASP ASP A . n 
D 2 457 GLU 457 469 469 GLU GLU A . n 
D 2 458 LYS 458 470 470 LYS LYS A . n 
D 2 459 ALA 459 471 471 ALA ALA A . n 
D 2 460 THR 460 472 472 THR THR A . n 
D 2 461 SER 461 473 473 SER SER A . n 
D 2 462 PRO 462 474 474 PRO PRO A . n 
D 2 463 ILE 463 475 475 ILE ILE A . n 
D 2 464 VAL 464 476 476 VAL VAL A . n 
D 2 465 PRO 465 477 477 PRO PRO A . n 
D 2 466 SER 466 478 478 SER SER A . n 
D 2 467 PHE 467 479 479 PHE PHE A . n 
D 2 468 ASP 468 480 480 ASP ASP A . n 
D 2 469 MET 469 481 481 MET MET A . n 
D 2 470 SER 470 482 482 SER SER A . n 
D 2 471 ASN 471 483 483 ASN ASN A . n 
D 2 472 GLU 472 484 484 GLU GLU A . n 
D 2 473 GLY 473 485 485 GLY GLY A . n 
D 2 474 SER 474 486 486 SER SER A . n 
D 2 475 TYR 475 487 487 TYR TYR A . n 
D 2 476 PHE 476 488 488 PHE PHE A . n 
D 2 477 PHE 477 489 489 PHE PHE A . n 
D 2 478 GLY 478 490 490 GLY GLY A . n 
D 2 479 ASP 479 491 ?   ?   ?   A . n 
D 2 480 ASN 480 492 ?   ?   ?   A . n 
D 2 481 ALA 481 493 ?   ?   ?   A . n 
D 2 482 GLU 482 494 ?   ?   ?   A . n 
D 2 483 GLU 483 495 ?   ?   ?   A . n 
D 2 484 TYR 484 496 ?   ?   ?   A . n 
D 2 485 ASP 485 497 ?   ?   ?   A . n 
D 2 486 ASN 486 498 ?   ?   ?   A . n 
D 2 487 LEU 487 499 ?   ?   ?   A . n 
D 2 488 GLU 488 500 ?   ?   ?   A . n 
D 2 489 HIS 489 501 ?   ?   ?   A . n 
D 2 490 HIS 490 502 ?   ?   ?   A . n 
D 2 491 HIS 491 503 ?   ?   ?   A . n 
D 2 492 HIS 492 504 ?   ?   ?   A . n 
D 2 493 HIS 493 505 ?   ?   ?   A . n 
D 2 494 HIS 494 506 ?   ?   ?   A . n 
# 
_pdbx_nonpoly_scheme.asym_id         E 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          A1IJK 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     101 
_pdbx_nonpoly_scheme.auth_seq_num    18 
_pdbx_nonpoly_scheme.pdb_mon_id      A1IJK 
_pdbx_nonpoly_scheme.auth_mon_id     6FM 
_pdbx_nonpoly_scheme.pdb_strand_id   C 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_pdbx_unobs_or_zero_occ_atoms.id               1 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id     C 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id     C 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id      18 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id     OP2 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id     ? 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id    B 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id    C 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id     12 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id    OP2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GAS 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GAS 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GAS 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9GAS 
_struct.title                        
'Focused reconstruction on strand 2 of the influenza A RNP-like particle double-stranded assembled with a 18-mer RNA.' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GAS 
_struct_keywords.text            'Nucleoprotein, RNA, complex, RNP-like, influenza virus, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9GAS         9GAS   ? 1 ? 1  
2 UNP Q1K9H2_I33A0 Q1K9H2 ? 2 
;TDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGG
PIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPR
RSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAEFE
DLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMACH
SAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTFSV
QRNLPFDRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDNAE
EYDN
;
15 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9GAS D 1 ? 18  ? 9GAS   1  ? 18  ? 1  18  
2 1 9GAS C 1 ? 18  ? 9GAS   7  ? 24  ? 7  24  
3 2 9GAS B 3 ? 486 ? Q1K9H2 15 ? 498 ? 15 498 
4 2 9GAS A 3 ? 486 ? Q1K9H2 15 ? 498 ? 15 498 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 9GAS HIS B 1   ? UNP Q1K9H2 ? ? 'expression tag' 13  1  
3 9GAS MET B 2   ? UNP Q1K9H2 ? ? 'expression tag' 14  2  
3 9GAS LEU B 487 ? UNP Q1K9H2 ? ? 'expression tag' 499 3  
3 9GAS GLU B 488 ? UNP Q1K9H2 ? ? 'expression tag' 500 4  
3 9GAS HIS B 489 ? UNP Q1K9H2 ? ? 'expression tag' 501 5  
3 9GAS HIS B 490 ? UNP Q1K9H2 ? ? 'expression tag' 502 6  
3 9GAS HIS B 491 ? UNP Q1K9H2 ? ? 'expression tag' 503 7  
3 9GAS HIS B 492 ? UNP Q1K9H2 ? ? 'expression tag' 504 8  
3 9GAS HIS B 493 ? UNP Q1K9H2 ? ? 'expression tag' 505 9  
3 9GAS HIS B 494 ? UNP Q1K9H2 ? ? 'expression tag' 506 10 
4 9GAS HIS A 1   ? UNP Q1K9H2 ? ? 'expression tag' 13  11 
4 9GAS MET A 2   ? UNP Q1K9H2 ? ? 'expression tag' 14  12 
4 9GAS LEU A 487 ? UNP Q1K9H2 ? ? 'expression tag' 499 13 
4 9GAS GLU A 488 ? UNP Q1K9H2 ? ? 'expression tag' 500 14 
4 9GAS HIS A 489 ? UNP Q1K9H2 ? ? 'expression tag' 501 15 
4 9GAS HIS A 490 ? UNP Q1K9H2 ? ? 'expression tag' 502 16 
4 9GAS HIS A 491 ? UNP Q1K9H2 ? ? 'expression tag' 503 17 
4 9GAS HIS A 492 ? UNP Q1K9H2 ? ? 'expression tag' 504 18 
4 9GAS HIS A 493 ? UNP Q1K9H2 ? ? 'expression tag' 505 19 
4 9GAS HIS A 494 ? UNP Q1K9H2 ? ? 'expression tag' 506 20 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP C 409 ? ALA C 416 ? ASP B 421 ALA B 428 1 ? 8  
HELX_P HELX_P2  AA2 ARG D 7   ? LYS D 36  ? ARG A 19  LYS A 48  1 ? 30 
HELX_P HELX_P3  AA3 SER D 38  ? ARG D 43  ? SER A 50  ARG A 55  1 ? 6  
HELX_P HELX_P4  AA4 LEU D 44  ? PHE D 59  ? LEU A 56  PHE A 71  1 ? 16 
HELX_P HELX_P5  AA5 ASP D 60  ? HIS D 70  ? ASP A 72  HIS A 82  1 ? 11 
HELX_P HELX_P6  AA6 LYS D 101 ? ASN D 112 ? LYS A 113 ASN A 124 1 ? 12 
HELX_P HELX_P7  AA7 ALA D 117 ? TYR D 136 ? ALA A 129 TYR A 148 1 ? 20 
HELX_P HELX_P8  AA8 ARG D 138 ? THR D 145 ? ARG A 150 THR A 157 1 ? 8  
HELX_P HELX_P9  AA9 MET D 151 ? MET D 155 ? MET A 163 MET A 167 5 ? 5  
HELX_P HELX_P10 AB1 PRO D 161 ? SER D 164 ? PRO A 173 SER A 176 5 ? 4  
HELX_P HELX_P11 AB2 GLY D 165 ? ALA D 170 ? GLY A 177 ALA A 182 1 ? 6  
HELX_P HELX_P12 AB3 GLY D 173 ? ASP D 191 ? GLY A 185 ASP A 203 1 ? 19 
HELX_P HELX_P13 AB4 ARG D 196 ? PHE D 218 ? ARG A 208 PHE A 230 1 ? 23 
HELX_P HELX_P14 AB5 THR D 220 ? GLU D 232 ? THR A 232 GLU A 244 1 ? 13 
HELX_P HELX_P15 AB6 GLY D 237 ? ALA D 251 ? GLY A 249 ALA A 263 1 ? 15 
HELX_P HELX_P16 AB7 PRO D 265 ? GLY D 276 ? PRO A 277 GLY A 288 1 ? 12 
HELX_P HELX_P17 AB8 ASP D 278 ? GLY D 283 ? ASP A 290 GLY A 295 1 ? 6  
HELX_P HELX_P18 AB9 ILE D 289 ? ASN D 297 ? ILE A 301 ASN A 309 1 ? 9  
HELX_P HELX_P19 AC1 ASN D 309 ? SER D 323 ? ASN A 321 SER A 335 1 ? 15 
HELX_P HELX_P20 AC2 ASP D 328 ? GLY D 337 ? ASP A 340 GLY A 349 1 ? 10 
HELX_P HELX_P21 AC3 PRO D 342 ? LEU D 346 ? PRO A 354 LEU A 358 5 ? 5  
HELX_P HELX_P22 AC4 ASP D 427 ? ALA D 439 ? ASP A 439 ALA A 451 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            covale1 
_struct_conn.conn_type_id                  covale 
_struct_conn.pdbx_leaving_atom_flag        one 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           B 
_struct_conn.ptnr1_label_comp_id           C 
_struct_conn.ptnr1_label_seq_id            12 
_struct_conn.ptnr1_label_atom_id           "O3'" 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           E 
_struct_conn.ptnr2_label_comp_id           A1IJK 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           C1 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            C 
_struct_conn.ptnr1_auth_comp_id            C 
_struct_conn.ptnr1_auth_seq_id             18 
_struct_conn.ptnr2_auth_asym_id            C 
_struct_conn.ptnr2_auth_comp_id            A1IJK 
_struct_conn.ptnr2_auth_seq_id             101 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               1.435 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS D 79  ? VAL D 88  ? LYS A 91  VAL A 100 
AA1 2 LYS D 91  ? ASP D 100 ? LYS A 103 ASP A 112 
AA2 1 TYR D 301 ? ILE D 304 ? TYR A 313 ILE A 316 
AA2 2 GLU D 363 ? THR D 366 ? GLU A 375 THR A 378 
AA3 1 TYR D 373 ? TRP D 374 ? TYR A 385 TRP A 386 
AA3 2 PHE D 452 ? GLU D 453 ? PHE A 464 GLU A 465 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL D 88  ? N VAL A 100 O LYS D 91  ? O LYS A 103 
AA2 1 2 N ILE D 304 ? N ILE A 316 O GLU D 363 ? O GLU A 375 
AA3 1 2 N TRP D 374 ? N TRP A 386 O PHE D 452 ? O PHE A 464 
# 
_pdbx_entry_details.entry_id                   9GAS 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            P 
_pdbx_validate_rmsd_bond.auth_asym_id_1            D 
_pdbx_validate_rmsd_bond.auth_comp_id_1            U 
_pdbx_validate_rmsd_bond.auth_seq_id_1             1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            OP3 
_pdbx_validate_rmsd_bond.auth_asym_id_2            D 
_pdbx_validate_rmsd_bond.auth_comp_id_2            U 
_pdbx_validate_rmsd_bond.auth_seq_id_2             1 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.478 
_pdbx_validate_rmsd_bond.bond_target_value         1.607 
_pdbx_validate_rmsd_bond.bond_deviation            -0.129 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.012 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG B 416 ? ? 41.51   142.83  
2  1 ASN A 125 ? ? 61.22   60.31   
3  1 MET A 163 ? ? -92.36  50.89   
4  1 MET A 167 ? ? -92.74  30.25   
5  1 ASN A 319 ? ? 60.69   60.77   
6  1 MET A 371 ? ? -85.30  49.60   
7  1 LEU A 381 ? ? -95.02  52.72   
8  1 PRO A 453 ? ? -79.30  43.05   
9  1 ASP A 480 ? ? -93.15  56.75   
10 1 MET A 481 ? ? -126.45 -169.97 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9GAS 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9GAS 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.08 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               276761 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               HELICAL 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       
;20 mM HEPES
150 mM NaCl
5 mM beta-mercaptoethanol
2 mM methyl-PEG8-NHS
;
_em_buffer.pH            7.5 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 'MULTIPLE SOURCES' COMPLEX 'complex NP-RNA' ? ? ? '1, 2' 
2 1 RECOMBINANT        COMPLEX RNA              ? ? ? 1      
3 1 RECOMBINANT        COMPLEX Nucleoprotein    ? ? ? 2      
# 
_em_imaging.entry_id                        9GAS 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS GLACIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           36000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_vitrification.entry_id              9GAS 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              98 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   298 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               '5 seconds blot at force 0' 
# 
_em_experiment.entry_id                9GAS 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   HELICAL 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 D C   8   ? A C   8   
2   1 Y 1 D U   9   ? A U   9   
3   1 Y 1 D C   10  ? A C   10  
4   1 Y 1 D U   11  ? A U   11  
5   1 Y 1 D C   12  ? A C   12  
6   1 Y 1 D U   13  ? A U   13  
7   1 Y 1 D C   14  ? A C   14  
8   1 Y 1 D U   15  ? A U   15  
9   1 Y 1 D C   16  ? A C   16  
10  1 Y 1 D U   17  ? A U   17  
11  1 Y 1 D C   18  ? A C   18  
12  1 Y 1 C U   7   ? B U   1   
13  1 Y 1 C U   19  ? B U   13  
14  1 Y 1 C C   20  ? B C   14  
15  1 Y 1 C U   21  ? B U   15  
16  1 Y 1 C C   22  ? B C   16  
17  1 Y 1 C U   23  ? B U   17  
18  1 Y 1 C C   24  ? B C   18  
19  1 Y 1 B HIS 13  ? C HIS 1   
20  1 Y 1 B MET 14  ? C MET 2   
21  1 Y 1 B THR 15  ? C THR 3   
22  1 Y 1 B ASP 16  ? C ASP 4   
23  1 Y 1 B GLY 17  ? C GLY 5   
24  1 Y 1 B GLU 18  ? C GLU 6   
25  1 Y 1 B ARG 19  ? C ARG 7   
26  1 Y 1 B GLN 20  ? C GLN 8   
27  1 Y 1 B ASN 21  ? C ASN 9   
28  1 Y 1 B ALA 22  ? C ALA 10  
29  1 Y 1 B THR 23  ? C THR 11  
30  1 Y 1 B GLU 24  ? C GLU 12  
31  1 Y 1 B ILE 25  ? C ILE 13  
32  1 Y 1 B ARG 26  ? C ARG 14  
33  1 Y 1 B ALA 27  ? C ALA 15  
34  1 Y 1 B SER 28  ? C SER 16  
35  1 Y 1 B VAL 29  ? C VAL 17  
36  1 Y 1 B GLY 30  ? C GLY 18  
37  1 Y 1 B LYS 31  ? C LYS 19  
38  1 Y 1 B MET 32  ? C MET 20  
39  1 Y 1 B ILE 33  ? C ILE 21  
40  1 Y 1 B ASP 34  ? C ASP 22  
41  1 Y 1 B GLY 35  ? C GLY 23  
42  1 Y 1 B ILE 36  ? C ILE 24  
43  1 Y 1 B GLY 37  ? C GLY 25  
44  1 Y 1 B ARG 38  ? C ARG 26  
45  1 Y 1 B PHE 39  ? C PHE 27  
46  1 Y 1 B TYR 40  ? C TYR 28  
47  1 Y 1 B ILE 41  ? C ILE 29  
48  1 Y 1 B GLN 42  ? C GLN 30  
49  1 Y 1 B MET 43  ? C MET 31  
50  1 Y 1 B CYS 44  ? C CYS 32  
51  1 Y 1 B THR 45  ? C THR 33  
52  1 Y 1 B GLU 46  ? C GLU 34  
53  1 Y 1 B LEU 47  ? C LEU 35  
54  1 Y 1 B LYS 48  ? C LYS 36  
55  1 Y 1 B LEU 49  ? C LEU 37  
56  1 Y 1 B SER 50  ? C SER 38  
57  1 Y 1 B ASP 51  ? C ASP 39  
58  1 Y 1 B TYR 52  ? C TYR 40  
59  1 Y 1 B GLU 53  ? C GLU 41  
60  1 Y 1 B GLY 54  ? C GLY 42  
61  1 Y 1 B ARG 55  ? C ARG 43  
62  1 Y 1 B LEU 56  ? C LEU 44  
63  1 Y 1 B ILE 57  ? C ILE 45  
64  1 Y 1 B GLN 58  ? C GLN 46  
65  1 Y 1 B ASN 59  ? C ASN 47  
66  1 Y 1 B SER 60  ? C SER 48  
67  1 Y 1 B LEU 61  ? C LEU 49  
68  1 Y 1 B THR 62  ? C THR 50  
69  1 Y 1 B ILE 63  ? C ILE 51  
70  1 Y 1 B GLU 64  ? C GLU 52  
71  1 Y 1 B ARG 65  ? C ARG 53  
72  1 Y 1 B MET 66  ? C MET 54  
73  1 Y 1 B VAL 67  ? C VAL 55  
74  1 Y 1 B LEU 68  ? C LEU 56  
75  1 Y 1 B SER 69  ? C SER 57  
76  1 Y 1 B ALA 70  ? C ALA 58  
77  1 Y 1 B PHE 71  ? C PHE 59  
78  1 Y 1 B ASP 72  ? C ASP 60  
79  1 Y 1 B GLU 73  ? C GLU 61  
80  1 Y 1 B ARG 74  ? C ARG 62  
81  1 Y 1 B ARG 75  ? C ARG 63  
82  1 Y 1 B ASN 76  ? C ASN 64  
83  1 Y 1 B LYS 77  ? C LYS 65  
84  1 Y 1 B TYR 78  ? C TYR 66  
85  1 Y 1 B LEU 79  ? C LEU 67  
86  1 Y 1 B GLU 80  ? C GLU 68  
87  1 Y 1 B GLU 81  ? C GLU 69  
88  1 Y 1 B HIS 82  ? C HIS 70  
89  1 Y 1 B PRO 83  ? C PRO 71  
90  1 Y 1 B SER 84  ? C SER 72  
91  1 Y 1 B ALA 85  ? C ALA 73  
92  1 Y 1 B GLY 86  ? C GLY 74  
93  1 Y 1 B LYS 87  ? C LYS 75  
94  1 Y 1 B ASP 88  ? C ASP 76  
95  1 Y 1 B PRO 89  ? C PRO 77  
96  1 Y 1 B LYS 90  ? C LYS 78  
97  1 Y 1 B LYS 91  ? C LYS 79  
98  1 Y 1 B THR 92  ? C THR 80  
99  1 Y 1 B GLY 93  ? C GLY 81  
100 1 Y 1 B GLY 94  ? C GLY 82  
101 1 Y 1 B PRO 95  ? C PRO 83  
102 1 Y 1 B ILE 96  ? C ILE 84  
103 1 Y 1 B TYR 97  ? C TYR 85  
104 1 Y 1 B ARG 98  ? C ARG 86  
105 1 Y 1 B ARG 99  ? C ARG 87  
106 1 Y 1 B VAL 100 ? C VAL 88  
107 1 Y 1 B ASP 101 ? C ASP 89  
108 1 Y 1 B GLY 102 ? C GLY 90  
109 1 Y 1 B LYS 103 ? C LYS 91  
110 1 Y 1 B TRP 104 ? C TRP 92  
111 1 Y 1 B ARG 105 ? C ARG 93  
112 1 Y 1 B ARG 106 ? C ARG 94  
113 1 Y 1 B GLU 107 ? C GLU 95  
114 1 Y 1 B LEU 108 ? C LEU 96  
115 1 Y 1 B ILE 109 ? C ILE 97  
116 1 Y 1 B LEU 110 ? C LEU 98  
117 1 Y 1 B TYR 111 ? C TYR 99  
118 1 Y 1 B ASP 112 ? C ASP 100 
119 1 Y 1 B LYS 113 ? C LYS 101 
120 1 Y 1 B GLU 114 ? C GLU 102 
121 1 Y 1 B GLU 115 ? C GLU 103 
122 1 Y 1 B ILE 116 ? C ILE 104 
123 1 Y 1 B ARG 117 ? C ARG 105 
124 1 Y 1 B ARG 118 ? C ARG 106 
125 1 Y 1 B ILE 119 ? C ILE 107 
126 1 Y 1 B TRP 120 ? C TRP 108 
127 1 Y 1 B ARG 121 ? C ARG 109 
128 1 Y 1 B GLN 122 ? C GLN 110 
129 1 Y 1 B ALA 123 ? C ALA 111 
130 1 Y 1 B ASN 124 ? C ASN 112 
131 1 Y 1 B ASN 125 ? C ASN 113 
132 1 Y 1 B GLY 126 ? C GLY 114 
133 1 Y 1 B ASP 127 ? C ASP 115 
134 1 Y 1 B ASP 128 ? C ASP 116 
135 1 Y 1 B ALA 129 ? C ALA 117 
136 1 Y 1 B THR 130 ? C THR 118 
137 1 Y 1 B ALA 131 ? C ALA 119 
138 1 Y 1 B GLY 132 ? C GLY 120 
139 1 Y 1 B LEU 133 ? C LEU 121 
140 1 Y 1 B THR 134 ? C THR 122 
141 1 Y 1 B HIS 135 ? C HIS 123 
142 1 Y 1 B MET 136 ? C MET 124 
143 1 Y 1 B MET 137 ? C MET 125 
144 1 Y 1 B ILE 138 ? C ILE 126 
145 1 Y 1 B TRP 139 ? C TRP 127 
146 1 Y 1 B HIS 140 ? C HIS 128 
147 1 Y 1 B SER 141 ? C SER 129 
148 1 Y 1 B ASN 142 ? C ASN 130 
149 1 Y 1 B LEU 143 ? C LEU 131 
150 1 Y 1 B ASN 144 ? C ASN 132 
151 1 Y 1 B ASP 145 ? C ASP 133 
152 1 Y 1 B ALA 146 ? C ALA 134 
153 1 Y 1 B THR 147 ? C THR 135 
154 1 Y 1 B TYR 148 ? C TYR 136 
155 1 Y 1 B GLN 149 ? C GLN 137 
156 1 Y 1 B ARG 150 ? C ARG 138 
157 1 Y 1 B THR 151 ? C THR 139 
158 1 Y 1 B ARG 152 ? C ARG 140 
159 1 Y 1 B ALA 153 ? C ALA 141 
160 1 Y 1 B LEU 154 ? C LEU 142 
161 1 Y 1 B VAL 155 ? C VAL 143 
162 1 Y 1 B ARG 156 ? C ARG 144 
163 1 Y 1 B THR 157 ? C THR 145 
164 1 Y 1 B GLY 158 ? C GLY 146 
165 1 Y 1 B MET 159 ? C MET 147 
166 1 Y 1 B ASP 160 ? C ASP 148 
167 1 Y 1 B PRO 161 ? C PRO 149 
168 1 Y 1 B ARG 162 ? C ARG 150 
169 1 Y 1 B MET 163 ? C MET 151 
170 1 Y 1 B CYS 164 ? C CYS 152 
171 1 Y 1 B SER 165 ? C SER 153 
172 1 Y 1 B LEU 166 ? C LEU 154 
173 1 Y 1 B MET 167 ? C MET 155 
174 1 Y 1 B GLN 168 ? C GLN 156 
175 1 Y 1 B GLY 169 ? C GLY 157 
176 1 Y 1 B SER 170 ? C SER 158 
177 1 Y 1 B THR 171 ? C THR 159 
178 1 Y 1 B LEU 172 ? C LEU 160 
179 1 Y 1 B PRO 173 ? C PRO 161 
180 1 Y 1 B ARG 174 ? C ARG 162 
181 1 Y 1 B ARG 175 ? C ARG 163 
182 1 Y 1 B SER 176 ? C SER 164 
183 1 Y 1 B GLY 177 ? C GLY 165 
184 1 Y 1 B ALA 178 ? C ALA 166 
185 1 Y 1 B ALA 179 ? C ALA 167 
186 1 Y 1 B GLY 180 ? C GLY 168 
187 1 Y 1 B ALA 181 ? C ALA 169 
188 1 Y 1 B ALA 182 ? C ALA 170 
189 1 Y 1 B VAL 183 ? C VAL 171 
190 1 Y 1 B LYS 184 ? C LYS 172 
191 1 Y 1 B GLY 185 ? C GLY 173 
192 1 Y 1 B VAL 186 ? C VAL 174 
193 1 Y 1 B GLY 187 ? C GLY 175 
194 1 Y 1 B THR 188 ? C THR 176 
195 1 Y 1 B MET 189 ? C MET 177 
196 1 Y 1 B VAL 190 ? C VAL 178 
197 1 Y 1 B MET 191 ? C MET 179 
198 1 Y 1 B GLU 192 ? C GLU 180 
199 1 Y 1 B LEU 193 ? C LEU 181 
200 1 Y 1 B ILE 194 ? C ILE 182 
201 1 Y 1 B ARG 195 ? C ARG 183 
202 1 Y 1 B MET 196 ? C MET 184 
203 1 Y 1 B ILE 197 ? C ILE 185 
204 1 Y 1 B LYS 198 ? C LYS 186 
205 1 Y 1 B ARG 199 ? C ARG 187 
206 1 Y 1 B GLY 200 ? C GLY 188 
207 1 Y 1 B ILE 201 ? C ILE 189 
208 1 Y 1 B ASN 202 ? C ASN 190 
209 1 Y 1 B ASP 203 ? C ASP 191 
210 1 Y 1 B ARG 204 ? C ARG 192 
211 1 Y 1 B ASN 205 ? C ASN 193 
212 1 Y 1 B PHE 206 ? C PHE 194 
213 1 Y 1 B TRP 207 ? C TRP 195 
214 1 Y 1 B ARG 208 ? C ARG 196 
215 1 Y 1 B GLY 209 ? C GLY 197 
216 1 Y 1 B GLU 210 ? C GLU 198 
217 1 Y 1 B ASN 211 ? C ASN 199 
218 1 Y 1 B GLY 212 ? C GLY 200 
219 1 Y 1 B ARG 213 ? C ARG 201 
220 1 Y 1 B ARG 214 ? C ARG 202 
221 1 Y 1 B THR 215 ? C THR 203 
222 1 Y 1 B ARG 216 ? C ARG 204 
223 1 Y 1 B ILE 217 ? C ILE 205 
224 1 Y 1 B ALA 218 ? C ALA 206 
225 1 Y 1 B TYR 219 ? C TYR 207 
226 1 Y 1 B GLU 220 ? C GLU 208 
227 1 Y 1 B ARG 221 ? C ARG 209 
228 1 Y 1 B MET 222 ? C MET 210 
229 1 Y 1 B CYS 223 ? C CYS 211 
230 1 Y 1 B ASN 224 ? C ASN 212 
231 1 Y 1 B ILE 225 ? C ILE 213 
232 1 Y 1 B LEU 226 ? C LEU 214 
233 1 Y 1 B LYS 227 ? C LYS 215 
234 1 Y 1 B GLY 228 ? C GLY 216 
235 1 Y 1 B LYS 229 ? C LYS 217 
236 1 Y 1 B PHE 230 ? C PHE 218 
237 1 Y 1 B GLN 231 ? C GLN 219 
238 1 Y 1 B THR 232 ? C THR 220 
239 1 Y 1 B ALA 233 ? C ALA 221 
240 1 Y 1 B ALA 234 ? C ALA 222 
241 1 Y 1 B GLN 235 ? C GLN 223 
242 1 Y 1 B ARG 236 ? C ARG 224 
243 1 Y 1 B THR 237 ? C THR 225 
244 1 Y 1 B MET 238 ? C MET 226 
245 1 Y 1 B VAL 239 ? C VAL 227 
246 1 Y 1 B ASP 240 ? C ASP 228 
247 1 Y 1 B GLN 241 ? C GLN 229 
248 1 Y 1 B VAL 242 ? C VAL 230 
249 1 Y 1 B ARG 243 ? C ARG 231 
250 1 Y 1 B GLU 244 ? C GLU 232 
251 1 Y 1 B SER 245 ? C SER 233 
252 1 Y 1 B ARG 246 ? C ARG 234 
253 1 Y 1 B ASN 247 ? C ASN 235 
254 1 Y 1 B PRO 248 ? C PRO 236 
255 1 Y 1 B GLY 249 ? C GLY 237 
256 1 Y 1 B ASN 250 ? C ASN 238 
257 1 Y 1 B ALA 251 ? C ALA 239 
258 1 Y 1 B GLU 252 ? C GLU 240 
259 1 Y 1 B PHE 253 ? C PHE 241 
260 1 Y 1 B GLU 254 ? C GLU 242 
261 1 Y 1 B ASP 255 ? C ASP 243 
262 1 Y 1 B LEU 256 ? C LEU 244 
263 1 Y 1 B ILE 257 ? C ILE 245 
264 1 Y 1 B PHE 258 ? C PHE 246 
265 1 Y 1 B LEU 259 ? C LEU 247 
266 1 Y 1 B ALA 260 ? C ALA 248 
267 1 Y 1 B ARG 261 ? C ARG 249 
268 1 Y 1 B SER 262 ? C SER 250 
269 1 Y 1 B ALA 263 ? C ALA 251 
270 1 Y 1 B LEU 264 ? C LEU 252 
271 1 Y 1 B ILE 265 ? C ILE 253 
272 1 Y 1 B LEU 266 ? C LEU 254 
273 1 Y 1 B ARG 267 ? C ARG 255 
274 1 Y 1 B GLY 268 ? C GLY 256 
275 1 Y 1 B SER 269 ? C SER 257 
276 1 Y 1 B VAL 270 ? C VAL 258 
277 1 Y 1 B ALA 271 ? C ALA 259 
278 1 Y 1 B HIS 272 ? C HIS 260 
279 1 Y 1 B LYS 273 ? C LYS 261 
280 1 Y 1 B SER 274 ? C SER 262 
281 1 Y 1 B CYS 275 ? C CYS 263 
282 1 Y 1 B LEU 276 ? C LEU 264 
283 1 Y 1 B PRO 277 ? C PRO 265 
284 1 Y 1 B ALA 278 ? C ALA 266 
285 1 Y 1 B CYS 279 ? C CYS 267 
286 1 Y 1 B VAL 280 ? C VAL 268 
287 1 Y 1 B TYR 281 ? C TYR 269 
288 1 Y 1 B GLY 282 ? C GLY 270 
289 1 Y 1 B SER 283 ? C SER 271 
290 1 Y 1 B ALA 284 ? C ALA 272 
291 1 Y 1 B VAL 285 ? C VAL 273 
292 1 Y 1 B ALA 286 ? C ALA 274 
293 1 Y 1 B SER 287 ? C SER 275 
294 1 Y 1 B GLY 288 ? C GLY 276 
295 1 Y 1 B TYR 289 ? C TYR 277 
296 1 Y 1 B ASP 290 ? C ASP 278 
297 1 Y 1 B PHE 291 ? C PHE 279 
298 1 Y 1 B GLU 292 ? C GLU 280 
299 1 Y 1 B ARG 293 ? C ARG 281 
300 1 Y 1 B GLU 294 ? C GLU 282 
301 1 Y 1 B GLY 295 ? C GLY 283 
302 1 Y 1 B TYR 296 ? C TYR 284 
303 1 Y 1 B SER 297 ? C SER 285 
304 1 Y 1 B LEU 298 ? C LEU 286 
305 1 Y 1 B VAL 299 ? C VAL 287 
306 1 Y 1 B GLY 300 ? C GLY 288 
307 1 Y 1 B ILE 301 ? C ILE 289 
308 1 Y 1 B ASP 302 ? C ASP 290 
309 1 Y 1 B PRO 303 ? C PRO 291 
310 1 Y 1 B PHE 304 ? C PHE 292 
311 1 Y 1 B ARG 305 ? C ARG 293 
312 1 Y 1 B LEU 306 ? C LEU 294 
313 1 Y 1 B LEU 307 ? C LEU 295 
314 1 Y 1 B GLN 308 ? C GLN 296 
315 1 Y 1 B ASN 309 ? C ASN 297 
316 1 Y 1 B SER 310 ? C SER 298 
317 1 Y 1 B GLN 311 ? C GLN 299 
318 1 Y 1 B VAL 312 ? C VAL 300 
319 1 Y 1 B TYR 313 ? C TYR 301 
320 1 Y 1 B SER 314 ? C SER 302 
321 1 Y 1 B LEU 315 ? C LEU 303 
322 1 Y 1 B ILE 316 ? C ILE 304 
323 1 Y 1 B ARG 317 ? C ARG 305 
324 1 Y 1 B PRO 318 ? C PRO 306 
325 1 Y 1 B ASN 319 ? C ASN 307 
326 1 Y 1 B GLU 320 ? C GLU 308 
327 1 Y 1 B ASN 321 ? C ASN 309 
328 1 Y 1 B PRO 322 ? C PRO 310 
329 1 Y 1 B ALA 323 ? C ALA 311 
330 1 Y 1 B HIS 324 ? C HIS 312 
331 1 Y 1 B LYS 325 ? C LYS 313 
332 1 Y 1 B SER 326 ? C SER 314 
333 1 Y 1 B GLN 327 ? C GLN 315 
334 1 Y 1 B LEU 328 ? C LEU 316 
335 1 Y 1 B VAL 329 ? C VAL 317 
336 1 Y 1 B TRP 330 ? C TRP 318 
337 1 Y 1 B MET 331 ? C MET 319 
338 1 Y 1 B ALA 332 ? C ALA 320 
339 1 Y 1 B CYS 333 ? C CYS 321 
340 1 Y 1 B HIS 334 ? C HIS 322 
341 1 Y 1 B SER 335 ? C SER 323 
342 1 Y 1 B ALA 336 ? C ALA 324 
343 1 Y 1 B ALA 337 ? C ALA 325 
344 1 Y 1 B PHE 338 ? C PHE 326 
345 1 Y 1 B GLU 339 ? C GLU 327 
346 1 Y 1 B ASP 340 ? C ASP 328 
347 1 Y 1 B LEU 341 ? C LEU 329 
348 1 Y 1 B ARG 342 ? C ARG 330 
349 1 Y 1 B VAL 343 ? C VAL 331 
350 1 Y 1 B SER 344 ? C SER 332 
351 1 Y 1 B SER 345 ? C SER 333 
352 1 Y 1 B PHE 346 ? C PHE 334 
353 1 Y 1 B ILE 347 ? C ILE 335 
354 1 Y 1 B ARG 348 ? C ARG 336 
355 1 Y 1 B GLY 349 ? C GLY 337 
356 1 Y 1 B THR 350 ? C THR 338 
357 1 Y 1 B LYS 351 ? C LYS 339 
358 1 Y 1 B VAL 352 ? C VAL 340 
359 1 Y 1 B VAL 353 ? C VAL 341 
360 1 Y 1 B PRO 354 ? C PRO 342 
361 1 Y 1 B ARG 355 ? C ARG 343 
362 1 Y 1 B GLY 356 ? C GLY 344 
363 1 Y 1 B LYS 357 ? C LYS 345 
364 1 Y 1 B LEU 358 ? C LEU 346 
365 1 Y 1 B SER 359 ? C SER 347 
366 1 Y 1 B THR 360 ? C THR 348 
367 1 Y 1 B ARG 361 ? C ARG 349 
368 1 Y 1 B GLY 362 ? C GLY 350 
369 1 Y 1 B VAL 363 ? C VAL 351 
370 1 Y 1 B GLN 364 ? C GLN 352 
371 1 Y 1 B ILE 365 ? C ILE 353 
372 1 Y 1 B ALA 366 ? C ALA 354 
373 1 Y 1 B SER 367 ? C SER 355 
374 1 Y 1 B ASN 368 ? C ASN 356 
375 1 Y 1 B GLU 369 ? C GLU 357 
376 1 Y 1 B ASN 370 ? C ASN 358 
377 1 Y 1 B MET 371 ? C MET 359 
378 1 Y 1 B GLU 372 ? C GLU 360 
379 1 Y 1 B THR 373 ? C THR 361 
380 1 Y 1 B MET 374 ? C MET 362 
381 1 Y 1 B GLU 375 ? C GLU 363 
382 1 Y 1 B SER 376 ? C SER 364 
383 1 Y 1 B SER 377 ? C SER 365 
384 1 Y 1 B THR 378 ? C THR 366 
385 1 Y 1 B LEU 379 ? C LEU 367 
386 1 Y 1 B GLU 380 ? C GLU 368 
387 1 Y 1 B LEU 381 ? C LEU 369 
388 1 Y 1 B ARG 382 ? C ARG 370 
389 1 Y 1 B SER 383 ? C SER 371 
390 1 Y 1 B ARG 384 ? C ARG 372 
391 1 Y 1 B TYR 385 ? C TYR 373 
392 1 Y 1 B TRP 386 ? C TRP 374 
393 1 Y 1 B ALA 387 ? C ALA 375 
394 1 Y 1 B ILE 388 ? C ILE 376 
395 1 Y 1 B ARG 389 ? C ARG 377 
396 1 Y 1 B THR 390 ? C THR 378 
397 1 Y 1 B ARG 391 ? C ARG 379 
398 1 Y 1 B SER 392 ? C SER 380 
399 1 Y 1 B GLY 393 ? C GLY 381 
400 1 Y 1 B GLY 394 ? C GLY 382 
401 1 Y 1 B ASN 395 ? C ASN 383 
402 1 Y 1 B THR 396 ? C THR 384 
403 1 Y 1 B ASN 397 ? C ASN 385 
404 1 Y 1 B GLN 398 ? C GLN 386 
405 1 Y 1 B GLN 399 ? C GLN 387 
406 1 Y 1 B ARG 400 ? C ARG 388 
407 1 Y 1 B ALA 401 ? C ALA 389 
408 1 Y 1 B SER 402 ? C SER 390 
409 1 Y 1 B GLY 431 ? C GLY 419 
410 1 Y 1 B ASN 432 ? C ASN 420 
411 1 Y 1 B THR 433 ? C THR 421 
412 1 Y 1 B GLU 434 ? C GLU 422 
413 1 Y 1 B GLY 435 ? C GLY 423 
414 1 Y 1 B ARG 436 ? C ARG 424 
415 1 Y 1 B THR 437 ? C THR 425 
416 1 Y 1 B SER 438 ? C SER 426 
417 1 Y 1 B ASP 439 ? C ASP 427 
418 1 Y 1 B MET 440 ? C MET 428 
419 1 Y 1 B ARG 441 ? C ARG 429 
420 1 Y 1 B THR 442 ? C THR 430 
421 1 Y 1 B GLU 443 ? C GLU 431 
422 1 Y 1 B ILE 444 ? C ILE 432 
423 1 Y 1 B ILE 445 ? C ILE 433 
424 1 Y 1 B ARG 446 ? C ARG 434 
425 1 Y 1 B LEU 447 ? C LEU 435 
426 1 Y 1 B MET 448 ? C MET 436 
427 1 Y 1 B GLU 449 ? C GLU 437 
428 1 Y 1 B SER 450 ? C SER 438 
429 1 Y 1 B ALA 451 ? C ALA 439 
430 1 Y 1 B ARG 452 ? C ARG 440 
431 1 Y 1 B PRO 453 ? C PRO 441 
432 1 Y 1 B GLU 454 ? C GLU 442 
433 1 Y 1 B ASP 455 ? C ASP 443 
434 1 Y 1 B VAL 456 ? C VAL 444 
435 1 Y 1 B SER 457 ? C SER 445 
436 1 Y 1 B PHE 458 ? C PHE 446 
437 1 Y 1 B GLN 459 ? C GLN 447 
438 1 Y 1 B GLY 460 ? C GLY 448 
439 1 Y 1 B ARG 461 ? C ARG 449 
440 1 Y 1 B GLY 462 ? C GLY 450 
441 1 Y 1 B VAL 463 ? C VAL 451 
442 1 Y 1 B PHE 464 ? C PHE 452 
443 1 Y 1 B GLU 465 ? C GLU 453 
444 1 Y 1 B LEU 466 ? C LEU 454 
445 1 Y 1 B SER 467 ? C SER 455 
446 1 Y 1 B ASP 468 ? C ASP 456 
447 1 Y 1 B GLU 469 ? C GLU 457 
448 1 Y 1 B LYS 470 ? C LYS 458 
449 1 Y 1 B ALA 471 ? C ALA 459 
450 1 Y 1 B THR 472 ? C THR 460 
451 1 Y 1 B SER 473 ? C SER 461 
452 1 Y 1 B PRO 474 ? C PRO 462 
453 1 Y 1 B ILE 475 ? C ILE 463 
454 1 Y 1 B VAL 476 ? C VAL 464 
455 1 Y 1 B PRO 477 ? C PRO 465 
456 1 Y 1 B SER 478 ? C SER 466 
457 1 Y 1 B PHE 479 ? C PHE 467 
458 1 Y 1 B ASP 480 ? C ASP 468 
459 1 Y 1 B MET 481 ? C MET 469 
460 1 Y 1 B SER 482 ? C SER 470 
461 1 Y 1 B ASN 483 ? C ASN 471 
462 1 Y 1 B GLU 484 ? C GLU 472 
463 1 Y 1 B GLY 485 ? C GLY 473 
464 1 Y 1 B SER 486 ? C SER 474 
465 1 Y 1 B TYR 487 ? C TYR 475 
466 1 Y 1 B PHE 488 ? C PHE 476 
467 1 Y 1 B PHE 489 ? C PHE 477 
468 1 Y 1 B GLY 490 ? C GLY 478 
469 1 Y 1 B ASP 491 ? C ASP 479 
470 1 Y 1 B ASN 492 ? C ASN 480 
471 1 Y 1 B ALA 493 ? C ALA 481 
472 1 Y 1 B GLU 494 ? C GLU 482 
473 1 Y 1 B GLU 495 ? C GLU 483 
474 1 Y 1 B TYR 496 ? C TYR 484 
475 1 Y 1 B ASP 497 ? C ASP 485 
476 1 Y 1 B ASN 498 ? C ASN 486 
477 1 Y 1 B LEU 499 ? C LEU 487 
478 1 Y 1 B GLU 500 ? C GLU 488 
479 1 Y 1 B HIS 501 ? C HIS 489 
480 1 Y 1 B HIS 502 ? C HIS 490 
481 1 Y 1 B HIS 503 ? C HIS 491 
482 1 Y 1 B HIS 504 ? C HIS 492 
483 1 Y 1 B HIS 505 ? C HIS 493 
484 1 Y 1 B HIS 506 ? C HIS 494 
485 1 Y 1 A HIS 13  ? D HIS 1   
486 1 Y 1 A MET 14  ? D MET 2   
487 1 Y 1 A THR 15  ? D THR 3   
488 1 Y 1 A ASP 16  ? D ASP 4   
489 1 Y 1 A GLY 17  ? D GLY 5   
490 1 Y 1 A GLN 398 ? D GLN 386 
491 1 Y 1 A GLN 399 ? D GLN 387 
492 1 Y 1 A ARG 400 ? D ARG 388 
493 1 Y 1 A ALA 401 ? D ALA 389 
494 1 Y 1 A SER 402 ? D SER 390 
495 1 Y 1 A SER 403 ? D SER 391 
496 1 Y 1 A GLY 404 ? D GLY 392 
497 1 Y 1 A GLN 405 ? D GLN 393 
498 1 Y 1 A ILE 406 ? D ILE 394 
499 1 Y 1 A SER 407 ? D SER 395 
500 1 Y 1 A ILE 408 ? D ILE 396 
501 1 Y 1 A GLN 409 ? D GLN 397 
502 1 Y 1 A PRO 410 ? D PRO 398 
503 1 Y 1 A THR 411 ? D THR 399 
504 1 Y 1 A PHE 412 ? D PHE 400 
505 1 Y 1 A SER 413 ? D SER 401 
506 1 Y 1 A VAL 414 ? D VAL 402 
507 1 Y 1 A GLN 415 ? D GLN 403 
508 1 Y 1 A ARG 416 ? D ARG 404 
509 1 Y 1 A ASN 417 ? D ASN 405 
510 1 Y 1 A LEU 418 ? D LEU 406 
511 1 Y 1 A PRO 419 ? D PRO 407 
512 1 Y 1 A PHE 420 ? D PHE 408 
513 1 Y 1 A ASP 421 ? D ASP 409 
514 1 Y 1 A ARG 422 ? D ARG 410 
515 1 Y 1 A PRO 423 ? D PRO 411 
516 1 Y 1 A THR 424 ? D THR 412 
517 1 Y 1 A ILE 425 ? D ILE 413 
518 1 Y 1 A MET 426 ? D MET 414 
519 1 Y 1 A ALA 427 ? D ALA 415 
520 1 Y 1 A ALA 428 ? D ALA 416 
521 1 Y 1 A PHE 429 ? D PHE 417 
522 1 Y 1 A THR 430 ? D THR 418 
523 1 Y 1 A GLY 431 ? D GLY 419 
524 1 Y 1 A ASN 432 ? D ASN 420 
525 1 Y 1 A THR 433 ? D THR 421 
526 1 Y 1 A GLU 434 ? D GLU 422 
527 1 Y 1 A GLY 435 ? D GLY 423 
528 1 Y 1 A ARG 436 ? D ARG 424 
529 1 Y 1 A ASP 491 ? D ASP 479 
530 1 Y 1 A ASN 492 ? D ASN 480 
531 1 Y 1 A ALA 493 ? D ALA 481 
532 1 Y 1 A GLU 494 ? D GLU 482 
533 1 Y 1 A GLU 495 ? D GLU 483 
534 1 Y 1 A TYR 496 ? D TYR 484 
535 1 Y 1 A ASP 497 ? D ASP 485 
536 1 Y 1 A ASN 498 ? D ASN 486 
537 1 Y 1 A LEU 499 ? D LEU 487 
538 1 Y 1 A GLU 500 ? D GLU 488 
539 1 Y 1 A HIS 501 ? D HIS 489 
540 1 Y 1 A HIS 502 ? D HIS 490 
541 1 Y 1 A HIS 503 ? D HIS 491 
542 1 Y 1 A HIS 504 ? D HIS 492 
543 1 Y 1 A HIS 505 ? D HIS 493 
544 1 Y 1 A HIS 506 ? D HIS 494 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1IJK C1     C N N 1   
A1IJK C2     C N R 2   
A1IJK C3     C N N 3   
A1IJK C6     C N N 4   
A1IJK C7     C N N 5   
A1IJK O4     O N N 6   
A1IJK O5     O N N 7   
A1IJK C8     C N N 8   
A1IJK C10    C N N 9   
A1IJK N9     N N N 10  
A1IJK C33    C N N 11  
A1IJK C34    C N N 12  
A1IJK C11    C Y N 13  
A1IJK C12    C Y N 14  
A1IJK C13    C Y N 15  
A1IJK C14    C Y N 16  
A1IJK C15    C Y N 17  
A1IJK C16    C Y N 18  
A1IJK C17    C N N 19  
A1IJK C20    C Y N 20  
A1IJK C21    C Y N 21  
A1IJK C22    C Y N 22  
A1IJK C24    C Y N 23  
A1IJK C25    C Y N 24  
A1IJK C27    C N N 25  
A1IJK C28    C N N 26  
A1IJK C29    C N N 27  
A1IJK C30    C N N 28  
A1IJK C31    C N N 29  
A1IJK C32    C N N 30  
A1IJK O18    O N N 31  
A1IJK O19    O N N 32  
A1IJK O23    O Y N 33  
A1IJK O26    O N N 34  
A1IJK O35    O N N 35  
A1IJK O36    O N N 36  
A1IJK H1     H N N 37  
A1IJK H2     H N N 38  
A1IJK H3     H N N 39  
A1IJK H4     H N N 40  
A1IJK H5     H N N 41  
A1IJK H6     H N N 42  
A1IJK H7     H N N 43  
A1IJK H8     H N N 44  
A1IJK H9     H N N 45  
A1IJK H10    H N N 46  
A1IJK H11    H N N 47  
A1IJK H12    H N N 48  
A1IJK H13    H N N 49  
A1IJK H14    H N N 50  
A1IJK H15    H N N 51  
A1IJK H16    H N N 52  
A1IJK H17    H N N 53  
A1IJK H18    H N N 54  
A1IJK H19    H N N 55  
A1IJK H20    H N N 56  
A1IJK H21    H N N 57  
A1IJK H22    H N N 58  
A1IJK H23    H N N 59  
A1IJK H24    H N N 60  
A1IJK H25    H N N 61  
A1IJK H26    H N N 62  
A1IJK H27    H N N 63  
ALA   N      N N N 64  
ALA   CA     C N S 65  
ALA   C      C N N 66  
ALA   O      O N N 67  
ALA   CB     C N N 68  
ALA   OXT    O N N 69  
ALA   H      H N N 70  
ALA   H2     H N N 71  
ALA   HA     H N N 72  
ALA   HB1    H N N 73  
ALA   HB2    H N N 74  
ALA   HB3    H N N 75  
ALA   HXT    H N N 76  
ARG   N      N N N 77  
ARG   CA     C N S 78  
ARG   C      C N N 79  
ARG   O      O N N 80  
ARG   CB     C N N 81  
ARG   CG     C N N 82  
ARG   CD     C N N 83  
ARG   NE     N N N 84  
ARG   CZ     C N N 85  
ARG   NH1    N N N 86  
ARG   NH2    N N N 87  
ARG   OXT    O N N 88  
ARG   H      H N N 89  
ARG   H2     H N N 90  
ARG   HA     H N N 91  
ARG   HB2    H N N 92  
ARG   HB3    H N N 93  
ARG   HG2    H N N 94  
ARG   HG3    H N N 95  
ARG   HD2    H N N 96  
ARG   HD3    H N N 97  
ARG   HE     H N N 98  
ARG   HH11   H N N 99  
ARG   HH12   H N N 100 
ARG   HH21   H N N 101 
ARG   HH22   H N N 102 
ARG   HXT    H N N 103 
ASN   N      N N N 104 
ASN   CA     C N S 105 
ASN   C      C N N 106 
ASN   O      O N N 107 
ASN   CB     C N N 108 
ASN   CG     C N N 109 
ASN   OD1    O N N 110 
ASN   ND2    N N N 111 
ASN   OXT    O N N 112 
ASN   H      H N N 113 
ASN   H2     H N N 114 
ASN   HA     H N N 115 
ASN   HB2    H N N 116 
ASN   HB3    H N N 117 
ASN   HD21   H N N 118 
ASN   HD22   H N N 119 
ASN   HXT    H N N 120 
ASP   N      N N N 121 
ASP   CA     C N S 122 
ASP   C      C N N 123 
ASP   O      O N N 124 
ASP   CB     C N N 125 
ASP   CG     C N N 126 
ASP   OD1    O N N 127 
ASP   OD2    O N N 128 
ASP   OXT    O N N 129 
ASP   H      H N N 130 
ASP   H2     H N N 131 
ASP   HA     H N N 132 
ASP   HB2    H N N 133 
ASP   HB3    H N N 134 
ASP   HD2    H N N 135 
ASP   HXT    H N N 136 
C     OP3    O N N 137 
C     P      P N N 138 
C     OP1    O N N 139 
C     OP2    O N N 140 
C     "O5'"  O N N 141 
C     "C5'"  C N N 142 
C     "C4'"  C N R 143 
C     "O4'"  O N N 144 
C     "C3'"  C N S 145 
C     "O3'"  O N N 146 
C     "C2'"  C N R 147 
C     "O2'"  O N N 148 
C     "C1'"  C N R 149 
C     N1     N N N 150 
C     C2     C N N 151 
C     O2     O N N 152 
C     N3     N N N 153 
C     C4     C N N 154 
C     N4     N N N 155 
C     C5     C N N 156 
C     C6     C N N 157 
C     HOP3   H N N 158 
C     HOP2   H N N 159 
C     "H5'"  H N N 160 
C     "H5''" H N N 161 
C     "H4'"  H N N 162 
C     "H3'"  H N N 163 
C     "HO3'" H N N 164 
C     "H2'"  H N N 165 
C     "HO2'" H N N 166 
C     "H1'"  H N N 167 
C     H41    H N N 168 
C     H42    H N N 169 
C     H5     H N N 170 
C     H6     H N N 171 
CYS   N      N N N 172 
CYS   CA     C N R 173 
CYS   C      C N N 174 
CYS   O      O N N 175 
CYS   CB     C N N 176 
CYS   SG     S N N 177 
CYS   OXT    O N N 178 
CYS   H      H N N 179 
CYS   H2     H N N 180 
CYS   HA     H N N 181 
CYS   HB2    H N N 182 
CYS   HB3    H N N 183 
CYS   HG     H N N 184 
CYS   HXT    H N N 185 
GLN   N      N N N 186 
GLN   CA     C N S 187 
GLN   C      C N N 188 
GLN   O      O N N 189 
GLN   CB     C N N 190 
GLN   CG     C N N 191 
GLN   CD     C N N 192 
GLN   OE1    O N N 193 
GLN   NE2    N N N 194 
GLN   OXT    O N N 195 
GLN   H      H N N 196 
GLN   H2     H N N 197 
GLN   HA     H N N 198 
GLN   HB2    H N N 199 
GLN   HB3    H N N 200 
GLN   HG2    H N N 201 
GLN   HG3    H N N 202 
GLN   HE21   H N N 203 
GLN   HE22   H N N 204 
GLN   HXT    H N N 205 
GLU   N      N N N 206 
GLU   CA     C N S 207 
GLU   C      C N N 208 
GLU   O      O N N 209 
GLU   CB     C N N 210 
GLU   CG     C N N 211 
GLU   CD     C N N 212 
GLU   OE1    O N N 213 
GLU   OE2    O N N 214 
GLU   OXT    O N N 215 
GLU   H      H N N 216 
GLU   H2     H N N 217 
GLU   HA     H N N 218 
GLU   HB2    H N N 219 
GLU   HB3    H N N 220 
GLU   HG2    H N N 221 
GLU   HG3    H N N 222 
GLU   HE2    H N N 223 
GLU   HXT    H N N 224 
GLY   N      N N N 225 
GLY   CA     C N N 226 
GLY   C      C N N 227 
GLY   O      O N N 228 
GLY   OXT    O N N 229 
GLY   H      H N N 230 
GLY   H2     H N N 231 
GLY   HA2    H N N 232 
GLY   HA3    H N N 233 
GLY   HXT    H N N 234 
HIS   N      N N N 235 
HIS   CA     C N S 236 
HIS   C      C N N 237 
HIS   O      O N N 238 
HIS   CB     C N N 239 
HIS   CG     C Y N 240 
HIS   ND1    N Y N 241 
HIS   CD2    C Y N 242 
HIS   CE1    C Y N 243 
HIS   NE2    N Y N 244 
HIS   OXT    O N N 245 
HIS   H      H N N 246 
HIS   H2     H N N 247 
HIS   HA     H N N 248 
HIS   HB2    H N N 249 
HIS   HB3    H N N 250 
HIS   HD1    H N N 251 
HIS   HD2    H N N 252 
HIS   HE1    H N N 253 
HIS   HE2    H N N 254 
HIS   HXT    H N N 255 
ILE   N      N N N 256 
ILE   CA     C N S 257 
ILE   C      C N N 258 
ILE   O      O N N 259 
ILE   CB     C N S 260 
ILE   CG1    C N N 261 
ILE   CG2    C N N 262 
ILE   CD1    C N N 263 
ILE   OXT    O N N 264 
ILE   H      H N N 265 
ILE   H2     H N N 266 
ILE   HA     H N N 267 
ILE   HB     H N N 268 
ILE   HG12   H N N 269 
ILE   HG13   H N N 270 
ILE   HG21   H N N 271 
ILE   HG22   H N N 272 
ILE   HG23   H N N 273 
ILE   HD11   H N N 274 
ILE   HD12   H N N 275 
ILE   HD13   H N N 276 
ILE   HXT    H N N 277 
LEU   N      N N N 278 
LEU   CA     C N S 279 
LEU   C      C N N 280 
LEU   O      O N N 281 
LEU   CB     C N N 282 
LEU   CG     C N N 283 
LEU   CD1    C N N 284 
LEU   CD2    C N N 285 
LEU   OXT    O N N 286 
LEU   H      H N N 287 
LEU   H2     H N N 288 
LEU   HA     H N N 289 
LEU   HB2    H N N 290 
LEU   HB3    H N N 291 
LEU   HG     H N N 292 
LEU   HD11   H N N 293 
LEU   HD12   H N N 294 
LEU   HD13   H N N 295 
LEU   HD21   H N N 296 
LEU   HD22   H N N 297 
LEU   HD23   H N N 298 
LEU   HXT    H N N 299 
LYS   N      N N N 300 
LYS   CA     C N S 301 
LYS   C      C N N 302 
LYS   O      O N N 303 
LYS   CB     C N N 304 
LYS   CG     C N N 305 
LYS   CD     C N N 306 
LYS   CE     C N N 307 
LYS   NZ     N N N 308 
LYS   OXT    O N N 309 
LYS   H      H N N 310 
LYS   H2     H N N 311 
LYS   HA     H N N 312 
LYS   HB2    H N N 313 
LYS   HB3    H N N 314 
LYS   HG2    H N N 315 
LYS   HG3    H N N 316 
LYS   HD2    H N N 317 
LYS   HD3    H N N 318 
LYS   HE2    H N N 319 
LYS   HE3    H N N 320 
LYS   HZ1    H N N 321 
LYS   HZ2    H N N 322 
LYS   HZ3    H N N 323 
LYS   HXT    H N N 324 
MET   N      N N N 325 
MET   CA     C N S 326 
MET   C      C N N 327 
MET   O      O N N 328 
MET   CB     C N N 329 
MET   CG     C N N 330 
MET   SD     S N N 331 
MET   CE     C N N 332 
MET   OXT    O N N 333 
MET   H      H N N 334 
MET   H2     H N N 335 
MET   HA     H N N 336 
MET   HB2    H N N 337 
MET   HB3    H N N 338 
MET   HG2    H N N 339 
MET   HG3    H N N 340 
MET   HE1    H N N 341 
MET   HE2    H N N 342 
MET   HE3    H N N 343 
MET   HXT    H N N 344 
PHE   N      N N N 345 
PHE   CA     C N S 346 
PHE   C      C N N 347 
PHE   O      O N N 348 
PHE   CB     C N N 349 
PHE   CG     C Y N 350 
PHE   CD1    C Y N 351 
PHE   CD2    C Y N 352 
PHE   CE1    C Y N 353 
PHE   CE2    C Y N 354 
PHE   CZ     C Y N 355 
PHE   OXT    O N N 356 
PHE   H      H N N 357 
PHE   H2     H N N 358 
PHE   HA     H N N 359 
PHE   HB2    H N N 360 
PHE   HB3    H N N 361 
PHE   HD1    H N N 362 
PHE   HD2    H N N 363 
PHE   HE1    H N N 364 
PHE   HE2    H N N 365 
PHE   HZ     H N N 366 
PHE   HXT    H N N 367 
PRO   N      N N N 368 
PRO   CA     C N S 369 
PRO   C      C N N 370 
PRO   O      O N N 371 
PRO   CB     C N N 372 
PRO   CG     C N N 373 
PRO   CD     C N N 374 
PRO   OXT    O N N 375 
PRO   H      H N N 376 
PRO   HA     H N N 377 
PRO   HB2    H N N 378 
PRO   HB3    H N N 379 
PRO   HG2    H N N 380 
PRO   HG3    H N N 381 
PRO   HD2    H N N 382 
PRO   HD3    H N N 383 
PRO   HXT    H N N 384 
SER   N      N N N 385 
SER   CA     C N S 386 
SER   C      C N N 387 
SER   O      O N N 388 
SER   CB     C N N 389 
SER   OG     O N N 390 
SER   OXT    O N N 391 
SER   H      H N N 392 
SER   H2     H N N 393 
SER   HA     H N N 394 
SER   HB2    H N N 395 
SER   HB3    H N N 396 
SER   HG     H N N 397 
SER   HXT    H N N 398 
THR   N      N N N 399 
THR   CA     C N S 400 
THR   C      C N N 401 
THR   O      O N N 402 
THR   CB     C N R 403 
THR   OG1    O N N 404 
THR   CG2    C N N 405 
THR   OXT    O N N 406 
THR   H      H N N 407 
THR   H2     H N N 408 
THR   HA     H N N 409 
THR   HB     H N N 410 
THR   HG1    H N N 411 
THR   HG21   H N N 412 
THR   HG22   H N N 413 
THR   HG23   H N N 414 
THR   HXT    H N N 415 
TRP   N      N N N 416 
TRP   CA     C N S 417 
TRP   C      C N N 418 
TRP   O      O N N 419 
TRP   CB     C N N 420 
TRP   CG     C Y N 421 
TRP   CD1    C Y N 422 
TRP   CD2    C Y N 423 
TRP   NE1    N Y N 424 
TRP   CE2    C Y N 425 
TRP   CE3    C Y N 426 
TRP   CZ2    C Y N 427 
TRP   CZ3    C Y N 428 
TRP   CH2    C Y N 429 
TRP   OXT    O N N 430 
TRP   H      H N N 431 
TRP   H2     H N N 432 
TRP   HA     H N N 433 
TRP   HB2    H N N 434 
TRP   HB3    H N N 435 
TRP   HD1    H N N 436 
TRP   HE1    H N N 437 
TRP   HE3    H N N 438 
TRP   HZ2    H N N 439 
TRP   HZ3    H N N 440 
TRP   HH2    H N N 441 
TRP   HXT    H N N 442 
TYR   N      N N N 443 
TYR   CA     C N S 444 
TYR   C      C N N 445 
TYR   O      O N N 446 
TYR   CB     C N N 447 
TYR   CG     C Y N 448 
TYR   CD1    C Y N 449 
TYR   CD2    C Y N 450 
TYR   CE1    C Y N 451 
TYR   CE2    C Y N 452 
TYR   CZ     C Y N 453 
TYR   OH     O N N 454 
TYR   OXT    O N N 455 
TYR   H      H N N 456 
TYR   H2     H N N 457 
TYR   HA     H N N 458 
TYR   HB2    H N N 459 
TYR   HB3    H N N 460 
TYR   HD1    H N N 461 
TYR   HD2    H N N 462 
TYR   HE1    H N N 463 
TYR   HE2    H N N 464 
TYR   HH     H N N 465 
TYR   HXT    H N N 466 
U     OP3    O N N 467 
U     P      P N N 468 
U     OP1    O N N 469 
U     OP2    O N N 470 
U     "O5'"  O N N 471 
U     "C5'"  C N N 472 
U     "C4'"  C N R 473 
U     "O4'"  O N N 474 
U     "C3'"  C N S 475 
U     "O3'"  O N N 476 
U     "C2'"  C N R 477 
U     "O2'"  O N N 478 
U     "C1'"  C N R 479 
U     N1     N N N 480 
U     C2     C N N 481 
U     O2     O N N 482 
U     N3     N N N 483 
U     C4     C N N 484 
U     O4     O N N 485 
U     C5     C N N 486 
U     C6     C N N 487 
U     HOP3   H N N 488 
U     HOP2   H N N 489 
U     "H5'"  H N N 490 
U     "H5''" H N N 491 
U     "H4'"  H N N 492 
U     "H3'"  H N N 493 
U     "HO3'" H N N 494 
U     "H2'"  H N N 495 
U     "HO2'" H N N 496 
U     "H1'"  H N N 497 
U     H3     H N N 498 
U     H5     H N N 499 
U     H6     H N N 500 
VAL   N      N N N 501 
VAL   CA     C N S 502 
VAL   C      C N N 503 
VAL   O      O N N 504 
VAL   CB     C N N 505 
VAL   CG1    C N N 506 
VAL   CG2    C N N 507 
VAL   OXT    O N N 508 
VAL   H      H N N 509 
VAL   H2     H N N 510 
VAL   HA     H N N 511 
VAL   HB     H N N 512 
VAL   HG11   H N N 513 
VAL   HG12   H N N 514 
VAL   HG13   H N N 515 
VAL   HG21   H N N 516 
VAL   HG22   H N N 517 
VAL   HG23   H N N 518 
VAL   HXT    H N N 519 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1IJK C2    O5     sing N N 1   
A1IJK C2    C1     sing N N 2   
A1IJK C2    C3     sing N N 3   
A1IJK O19   C17    doub N N 4   
A1IJK C13   C12    doub Y N 5   
A1IJK C13   C14    sing Y N 6   
A1IJK C12   C11    sing Y N 7   
A1IJK O4    C3     sing N N 8   
A1IJK O4    C6     sing N N 9   
A1IJK N9    C8     sing N N 10  
A1IJK N9    C10    sing N N 11  
A1IJK C8    C7     sing N N 12  
A1IJK C17   C14    sing N N 13  
A1IJK C17   O18    sing N N 14  
A1IJK C14   C15    doub Y N 15  
A1IJK C11   C10    sing N N 16  
A1IJK C11   C16    doub Y N 17  
A1IJK C10   O26    doub N N 18  
A1IJK C6    C7     sing N N 19  
A1IJK C15   C16    sing Y N 20  
A1IJK C15   C20    sing N N 21  
A1IJK C29   C30    doub N N 22  
A1IJK C29   C28    sing N N 23  
A1IJK C30   C21    sing N N 24  
A1IJK C20   C21    doub Y N 25  
A1IJK C20   C25    sing Y N 26  
A1IJK C21   C22    sing Y N 27  
A1IJK C28   O35    doub N N 28  
A1IJK C28   C27    sing N N 29  
A1IJK C22   C27    sing N N 30  
A1IJK C22   O23    doub Y N 31  
A1IJK C25   C34    sing N N 32  
A1IJK C25   C24    doub Y N 33  
A1IJK C34   C33    doub N N 34  
A1IJK O23   C24    sing Y N 35  
A1IJK C24   C31    sing N N 36  
A1IJK C33   C32    sing N N 37  
A1IJK C31   C32    sing N N 38  
A1IJK C32   O36    doub N N 39  
A1IJK C1    H1     sing N N 40  
A1IJK C1    H2     sing N N 41  
A1IJK C1    H3     sing N N 42  
A1IJK C2    H4     sing N N 43  
A1IJK C3    H5     sing N N 44  
A1IJK C3    H6     sing N N 45  
A1IJK C6    H7     sing N N 46  
A1IJK C6    H8     sing N N 47  
A1IJK C7    H9     sing N N 48  
A1IJK C7    H10    sing N N 49  
A1IJK O5    H11    sing N N 50  
A1IJK C8    H12    sing N N 51  
A1IJK C8    H13    sing N N 52  
A1IJK N9    H14    sing N N 53  
A1IJK C33   H15    sing N N 54  
A1IJK C34   H16    sing N N 55  
A1IJK C12   H17    sing N N 56  
A1IJK C13   H18    sing N N 57  
A1IJK C16   H19    sing N N 58  
A1IJK C27   H20    sing N N 59  
A1IJK C27   H21    sing N N 60  
A1IJK C29   H22    sing N N 61  
A1IJK C30   H23    sing N N 62  
A1IJK C31   H24    sing N N 63  
A1IJK C31   H25    sing N N 64  
A1IJK O18   H26    sing N N 65  
A1IJK O23   H27    sing N N 66  
ALA   N     CA     sing N N 67  
ALA   N     H      sing N N 68  
ALA   N     H2     sing N N 69  
ALA   CA    C      sing N N 70  
ALA   CA    CB     sing N N 71  
ALA   CA    HA     sing N N 72  
ALA   C     O      doub N N 73  
ALA   C     OXT    sing N N 74  
ALA   CB    HB1    sing N N 75  
ALA   CB    HB2    sing N N 76  
ALA   CB    HB3    sing N N 77  
ALA   OXT   HXT    sing N N 78  
ARG   N     CA     sing N N 79  
ARG   N     H      sing N N 80  
ARG   N     H2     sing N N 81  
ARG   CA    C      sing N N 82  
ARG   CA    CB     sing N N 83  
ARG   CA    HA     sing N N 84  
ARG   C     O      doub N N 85  
ARG   C     OXT    sing N N 86  
ARG   CB    CG     sing N N 87  
ARG   CB    HB2    sing N N 88  
ARG   CB    HB3    sing N N 89  
ARG   CG    CD     sing N N 90  
ARG   CG    HG2    sing N N 91  
ARG   CG    HG3    sing N N 92  
ARG   CD    NE     sing N N 93  
ARG   CD    HD2    sing N N 94  
ARG   CD    HD3    sing N N 95  
ARG   NE    CZ     sing N N 96  
ARG   NE    HE     sing N N 97  
ARG   CZ    NH1    sing N N 98  
ARG   CZ    NH2    doub N N 99  
ARG   NH1   HH11   sing N N 100 
ARG   NH1   HH12   sing N N 101 
ARG   NH2   HH21   sing N N 102 
ARG   NH2   HH22   sing N N 103 
ARG   OXT   HXT    sing N N 104 
ASN   N     CA     sing N N 105 
ASN   N     H      sing N N 106 
ASN   N     H2     sing N N 107 
ASN   CA    C      sing N N 108 
ASN   CA    CB     sing N N 109 
ASN   CA    HA     sing N N 110 
ASN   C     O      doub N N 111 
ASN   C     OXT    sing N N 112 
ASN   CB    CG     sing N N 113 
ASN   CB    HB2    sing N N 114 
ASN   CB    HB3    sing N N 115 
ASN   CG    OD1    doub N N 116 
ASN   CG    ND2    sing N N 117 
ASN   ND2   HD21   sing N N 118 
ASN   ND2   HD22   sing N N 119 
ASN   OXT   HXT    sing N N 120 
ASP   N     CA     sing N N 121 
ASP   N     H      sing N N 122 
ASP   N     H2     sing N N 123 
ASP   CA    C      sing N N 124 
ASP   CA    CB     sing N N 125 
ASP   CA    HA     sing N N 126 
ASP   C     O      doub N N 127 
ASP   C     OXT    sing N N 128 
ASP   CB    CG     sing N N 129 
ASP   CB    HB2    sing N N 130 
ASP   CB    HB3    sing N N 131 
ASP   CG    OD1    doub N N 132 
ASP   CG    OD2    sing N N 133 
ASP   OD2   HD2    sing N N 134 
ASP   OXT   HXT    sing N N 135 
C     OP3   P      sing N N 136 
C     OP3   HOP3   sing N N 137 
C     P     OP1    doub N N 138 
C     P     OP2    sing N N 139 
C     P     "O5'"  sing N N 140 
C     OP2   HOP2   sing N N 141 
C     "O5'" "C5'"  sing N N 142 
C     "C5'" "C4'"  sing N N 143 
C     "C5'" "H5'"  sing N N 144 
C     "C5'" "H5''" sing N N 145 
C     "C4'" "O4'"  sing N N 146 
C     "C4'" "C3'"  sing N N 147 
C     "C4'" "H4'"  sing N N 148 
C     "O4'" "C1'"  sing N N 149 
C     "C3'" "O3'"  sing N N 150 
C     "C3'" "C2'"  sing N N 151 
C     "C3'" "H3'"  sing N N 152 
C     "O3'" "HO3'" sing N N 153 
C     "C2'" "O2'"  sing N N 154 
C     "C2'" "C1'"  sing N N 155 
C     "C2'" "H2'"  sing N N 156 
C     "O2'" "HO2'" sing N N 157 
C     "C1'" N1     sing N N 158 
C     "C1'" "H1'"  sing N N 159 
C     N1    C2     sing N N 160 
C     N1    C6     sing N N 161 
C     C2    O2     doub N N 162 
C     C2    N3     sing N N 163 
C     N3    C4     doub N N 164 
C     C4    N4     sing N N 165 
C     C4    C5     sing N N 166 
C     N4    H41    sing N N 167 
C     N4    H42    sing N N 168 
C     C5    C6     doub N N 169 
C     C5    H5     sing N N 170 
C     C6    H6     sing N N 171 
CYS   N     CA     sing N N 172 
CYS   N     H      sing N N 173 
CYS   N     H2     sing N N 174 
CYS   CA    C      sing N N 175 
CYS   CA    CB     sing N N 176 
CYS   CA    HA     sing N N 177 
CYS   C     O      doub N N 178 
CYS   C     OXT    sing N N 179 
CYS   CB    SG     sing N N 180 
CYS   CB    HB2    sing N N 181 
CYS   CB    HB3    sing N N 182 
CYS   SG    HG     sing N N 183 
CYS   OXT   HXT    sing N N 184 
GLN   N     CA     sing N N 185 
GLN   N     H      sing N N 186 
GLN   N     H2     sing N N 187 
GLN   CA    C      sing N N 188 
GLN   CA    CB     sing N N 189 
GLN   CA    HA     sing N N 190 
GLN   C     O      doub N N 191 
GLN   C     OXT    sing N N 192 
GLN   CB    CG     sing N N 193 
GLN   CB    HB2    sing N N 194 
GLN   CB    HB3    sing N N 195 
GLN   CG    CD     sing N N 196 
GLN   CG    HG2    sing N N 197 
GLN   CG    HG3    sing N N 198 
GLN   CD    OE1    doub N N 199 
GLN   CD    NE2    sing N N 200 
GLN   NE2   HE21   sing N N 201 
GLN   NE2   HE22   sing N N 202 
GLN   OXT   HXT    sing N N 203 
GLU   N     CA     sing N N 204 
GLU   N     H      sing N N 205 
GLU   N     H2     sing N N 206 
GLU   CA    C      sing N N 207 
GLU   CA    CB     sing N N 208 
GLU   CA    HA     sing N N 209 
GLU   C     O      doub N N 210 
GLU   C     OXT    sing N N 211 
GLU   CB    CG     sing N N 212 
GLU   CB    HB2    sing N N 213 
GLU   CB    HB3    sing N N 214 
GLU   CG    CD     sing N N 215 
GLU   CG    HG2    sing N N 216 
GLU   CG    HG3    sing N N 217 
GLU   CD    OE1    doub N N 218 
GLU   CD    OE2    sing N N 219 
GLU   OE2   HE2    sing N N 220 
GLU   OXT   HXT    sing N N 221 
GLY   N     CA     sing N N 222 
GLY   N     H      sing N N 223 
GLY   N     H2     sing N N 224 
GLY   CA    C      sing N N 225 
GLY   CA    HA2    sing N N 226 
GLY   CA    HA3    sing N N 227 
GLY   C     O      doub N N 228 
GLY   C     OXT    sing N N 229 
GLY   OXT   HXT    sing N N 230 
HIS   N     CA     sing N N 231 
HIS   N     H      sing N N 232 
HIS   N     H2     sing N N 233 
HIS   CA    C      sing N N 234 
HIS   CA    CB     sing N N 235 
HIS   CA    HA     sing N N 236 
HIS   C     O      doub N N 237 
HIS   C     OXT    sing N N 238 
HIS   CB    CG     sing N N 239 
HIS   CB    HB2    sing N N 240 
HIS   CB    HB3    sing N N 241 
HIS   CG    ND1    sing Y N 242 
HIS   CG    CD2    doub Y N 243 
HIS   ND1   CE1    doub Y N 244 
HIS   ND1   HD1    sing N N 245 
HIS   CD2   NE2    sing Y N 246 
HIS   CD2   HD2    sing N N 247 
HIS   CE1   NE2    sing Y N 248 
HIS   CE1   HE1    sing N N 249 
HIS   NE2   HE2    sing N N 250 
HIS   OXT   HXT    sing N N 251 
ILE   N     CA     sing N N 252 
ILE   N     H      sing N N 253 
ILE   N     H2     sing N N 254 
ILE   CA    C      sing N N 255 
ILE   CA    CB     sing N N 256 
ILE   CA    HA     sing N N 257 
ILE   C     O      doub N N 258 
ILE   C     OXT    sing N N 259 
ILE   CB    CG1    sing N N 260 
ILE   CB    CG2    sing N N 261 
ILE   CB    HB     sing N N 262 
ILE   CG1   CD1    sing N N 263 
ILE   CG1   HG12   sing N N 264 
ILE   CG1   HG13   sing N N 265 
ILE   CG2   HG21   sing N N 266 
ILE   CG2   HG22   sing N N 267 
ILE   CG2   HG23   sing N N 268 
ILE   CD1   HD11   sing N N 269 
ILE   CD1   HD12   sing N N 270 
ILE   CD1   HD13   sing N N 271 
ILE   OXT   HXT    sing N N 272 
LEU   N     CA     sing N N 273 
LEU   N     H      sing N N 274 
LEU   N     H2     sing N N 275 
LEU   CA    C      sing N N 276 
LEU   CA    CB     sing N N 277 
LEU   CA    HA     sing N N 278 
LEU   C     O      doub N N 279 
LEU   C     OXT    sing N N 280 
LEU   CB    CG     sing N N 281 
LEU   CB    HB2    sing N N 282 
LEU   CB    HB3    sing N N 283 
LEU   CG    CD1    sing N N 284 
LEU   CG    CD2    sing N N 285 
LEU   CG    HG     sing N N 286 
LEU   CD1   HD11   sing N N 287 
LEU   CD1   HD12   sing N N 288 
LEU   CD1   HD13   sing N N 289 
LEU   CD2   HD21   sing N N 290 
LEU   CD2   HD22   sing N N 291 
LEU   CD2   HD23   sing N N 292 
LEU   OXT   HXT    sing N N 293 
LYS   N     CA     sing N N 294 
LYS   N     H      sing N N 295 
LYS   N     H2     sing N N 296 
LYS   CA    C      sing N N 297 
LYS   CA    CB     sing N N 298 
LYS   CA    HA     sing N N 299 
LYS   C     O      doub N N 300 
LYS   C     OXT    sing N N 301 
LYS   CB    CG     sing N N 302 
LYS   CB    HB2    sing N N 303 
LYS   CB    HB3    sing N N 304 
LYS   CG    CD     sing N N 305 
LYS   CG    HG2    sing N N 306 
LYS   CG    HG3    sing N N 307 
LYS   CD    CE     sing N N 308 
LYS   CD    HD2    sing N N 309 
LYS   CD    HD3    sing N N 310 
LYS   CE    NZ     sing N N 311 
LYS   CE    HE2    sing N N 312 
LYS   CE    HE3    sing N N 313 
LYS   NZ    HZ1    sing N N 314 
LYS   NZ    HZ2    sing N N 315 
LYS   NZ    HZ3    sing N N 316 
LYS   OXT   HXT    sing N N 317 
MET   N     CA     sing N N 318 
MET   N     H      sing N N 319 
MET   N     H2     sing N N 320 
MET   CA    C      sing N N 321 
MET   CA    CB     sing N N 322 
MET   CA    HA     sing N N 323 
MET   C     O      doub N N 324 
MET   C     OXT    sing N N 325 
MET   CB    CG     sing N N 326 
MET   CB    HB2    sing N N 327 
MET   CB    HB3    sing N N 328 
MET   CG    SD     sing N N 329 
MET   CG    HG2    sing N N 330 
MET   CG    HG3    sing N N 331 
MET   SD    CE     sing N N 332 
MET   CE    HE1    sing N N 333 
MET   CE    HE2    sing N N 334 
MET   CE    HE3    sing N N 335 
MET   OXT   HXT    sing N N 336 
PHE   N     CA     sing N N 337 
PHE   N     H      sing N N 338 
PHE   N     H2     sing N N 339 
PHE   CA    C      sing N N 340 
PHE   CA    CB     sing N N 341 
PHE   CA    HA     sing N N 342 
PHE   C     O      doub N N 343 
PHE   C     OXT    sing N N 344 
PHE   CB    CG     sing N N 345 
PHE   CB    HB2    sing N N 346 
PHE   CB    HB3    sing N N 347 
PHE   CG    CD1    doub Y N 348 
PHE   CG    CD2    sing Y N 349 
PHE   CD1   CE1    sing Y N 350 
PHE   CD1   HD1    sing N N 351 
PHE   CD2   CE2    doub Y N 352 
PHE   CD2   HD2    sing N N 353 
PHE   CE1   CZ     doub Y N 354 
PHE   CE1   HE1    sing N N 355 
PHE   CE2   CZ     sing Y N 356 
PHE   CE2   HE2    sing N N 357 
PHE   CZ    HZ     sing N N 358 
PHE   OXT   HXT    sing N N 359 
PRO   N     CA     sing N N 360 
PRO   N     CD     sing N N 361 
PRO   N     H      sing N N 362 
PRO   CA    C      sing N N 363 
PRO   CA    CB     sing N N 364 
PRO   CA    HA     sing N N 365 
PRO   C     O      doub N N 366 
PRO   C     OXT    sing N N 367 
PRO   CB    CG     sing N N 368 
PRO   CB    HB2    sing N N 369 
PRO   CB    HB3    sing N N 370 
PRO   CG    CD     sing N N 371 
PRO   CG    HG2    sing N N 372 
PRO   CG    HG3    sing N N 373 
PRO   CD    HD2    sing N N 374 
PRO   CD    HD3    sing N N 375 
PRO   OXT   HXT    sing N N 376 
SER   N     CA     sing N N 377 
SER   N     H      sing N N 378 
SER   N     H2     sing N N 379 
SER   CA    C      sing N N 380 
SER   CA    CB     sing N N 381 
SER   CA    HA     sing N N 382 
SER   C     O      doub N N 383 
SER   C     OXT    sing N N 384 
SER   CB    OG     sing N N 385 
SER   CB    HB2    sing N N 386 
SER   CB    HB3    sing N N 387 
SER   OG    HG     sing N N 388 
SER   OXT   HXT    sing N N 389 
THR   N     CA     sing N N 390 
THR   N     H      sing N N 391 
THR   N     H2     sing N N 392 
THR   CA    C      sing N N 393 
THR   CA    CB     sing N N 394 
THR   CA    HA     sing N N 395 
THR   C     O      doub N N 396 
THR   C     OXT    sing N N 397 
THR   CB    OG1    sing N N 398 
THR   CB    CG2    sing N N 399 
THR   CB    HB     sing N N 400 
THR   OG1   HG1    sing N N 401 
THR   CG2   HG21   sing N N 402 
THR   CG2   HG22   sing N N 403 
THR   CG2   HG23   sing N N 404 
THR   OXT   HXT    sing N N 405 
TRP   N     CA     sing N N 406 
TRP   N     H      sing N N 407 
TRP   N     H2     sing N N 408 
TRP   CA    C      sing N N 409 
TRP   CA    CB     sing N N 410 
TRP   CA    HA     sing N N 411 
TRP   C     O      doub N N 412 
TRP   C     OXT    sing N N 413 
TRP   CB    CG     sing N N 414 
TRP   CB    HB2    sing N N 415 
TRP   CB    HB3    sing N N 416 
TRP   CG    CD1    doub Y N 417 
TRP   CG    CD2    sing Y N 418 
TRP   CD1   NE1    sing Y N 419 
TRP   CD1   HD1    sing N N 420 
TRP   CD2   CE2    doub Y N 421 
TRP   CD2   CE3    sing Y N 422 
TRP   NE1   CE2    sing Y N 423 
TRP   NE1   HE1    sing N N 424 
TRP   CE2   CZ2    sing Y N 425 
TRP   CE3   CZ3    doub Y N 426 
TRP   CE3   HE3    sing N N 427 
TRP   CZ2   CH2    doub Y N 428 
TRP   CZ2   HZ2    sing N N 429 
TRP   CZ3   CH2    sing Y N 430 
TRP   CZ3   HZ3    sing N N 431 
TRP   CH2   HH2    sing N N 432 
TRP   OXT   HXT    sing N N 433 
TYR   N     CA     sing N N 434 
TYR   N     H      sing N N 435 
TYR   N     H2     sing N N 436 
TYR   CA    C      sing N N 437 
TYR   CA    CB     sing N N 438 
TYR   CA    HA     sing N N 439 
TYR   C     O      doub N N 440 
TYR   C     OXT    sing N N 441 
TYR   CB    CG     sing N N 442 
TYR   CB    HB2    sing N N 443 
TYR   CB    HB3    sing N N 444 
TYR   CG    CD1    doub Y N 445 
TYR   CG    CD2    sing Y N 446 
TYR   CD1   CE1    sing Y N 447 
TYR   CD1   HD1    sing N N 448 
TYR   CD2   CE2    doub Y N 449 
TYR   CD2   HD2    sing N N 450 
TYR   CE1   CZ     doub Y N 451 
TYR   CE1   HE1    sing N N 452 
TYR   CE2   CZ     sing Y N 453 
TYR   CE2   HE2    sing N N 454 
TYR   CZ    OH     sing N N 455 
TYR   OH    HH     sing N N 456 
TYR   OXT   HXT    sing N N 457 
U     OP3   P      sing N N 458 
U     OP3   HOP3   sing N N 459 
U     P     OP1    doub N N 460 
U     P     OP2    sing N N 461 
U     P     "O5'"  sing N N 462 
U     OP2   HOP2   sing N N 463 
U     "O5'" "C5'"  sing N N 464 
U     "C5'" "C4'"  sing N N 465 
U     "C5'" "H5'"  sing N N 466 
U     "C5'" "H5''" sing N N 467 
U     "C4'" "O4'"  sing N N 468 
U     "C4'" "C3'"  sing N N 469 
U     "C4'" "H4'"  sing N N 470 
U     "O4'" "C1'"  sing N N 471 
U     "C3'" "O3'"  sing N N 472 
U     "C3'" "C2'"  sing N N 473 
U     "C3'" "H3'"  sing N N 474 
U     "O3'" "HO3'" sing N N 475 
U     "C2'" "O2'"  sing N N 476 
U     "C2'" "C1'"  sing N N 477 
U     "C2'" "H2'"  sing N N 478 
U     "O2'" "HO2'" sing N N 479 
U     "C1'" N1     sing N N 480 
U     "C1'" "H1'"  sing N N 481 
U     N1    C2     sing N N 482 
U     N1    C6     sing N N 483 
U     C2    O2     doub N N 484 
U     C2    N3     sing N N 485 
U     N3    C4     sing N N 486 
U     N3    H3     sing N N 487 
U     C4    O4     doub N N 488 
U     C4    C5     sing N N 489 
U     C5    C6     doub N N 490 
U     C5    H5     sing N N 491 
U     C6    H6     sing N N 492 
VAL   N     CA     sing N N 493 
VAL   N     H      sing N N 494 
VAL   N     H2     sing N N 495 
VAL   CA    C      sing N N 496 
VAL   CA    CB     sing N N 497 
VAL   CA    HA     sing N N 498 
VAL   C     O      doub N N 499 
VAL   C     OXT    sing N N 500 
VAL   CB    CG1    sing N N 501 
VAL   CB    CG2    sing N N 502 
VAL   CB    HB     sing N N 503 
VAL   CG1   HG11   sing N N 504 
VAL   CG1   HG12   sing N N 505 
VAL   CG1   HG13   sing N N 506 
VAL   CG2   HG21   sing N N 507 
VAL   CG2   HG22   sing N N 508 
VAL   CG2   HG23   sing N N 509 
VAL   OXT   HXT    sing N N 510 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-29 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9GAS 
_em_admin.last_update        2025-02-12 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              
'Focused reconstruction on strand 2 of the influenza A RNP-like particle double-stranded assembled with a 18-mer RNA.' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 20  mM ?    1 HEPES                   
1 150 mM NaCl 2 NaCl                    
1 5   mM ?    3 beta-mercaptoethanol    
1 2   mM ?    4 methyl-PEG8-NHS         
1 4   uM ?    5 
;RNA (5'P-(UC)6-FAM3')
;
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 2 2 32630 'synthetic construct' ? ? ? ? ? 
? ? 3 3 11320 'Influenza A virus'   ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 2 2 32630  'synthetic construct'        ? ? 
? 3 3 469008 'Escherichia coli BL21(DE3)' ? ? 
# 
_em_helical_entity.id                             1 
_em_helical_entity.image_processing_id            1 
_em_helical_entity.details                        ? 
_em_helical_entity.axial_symmetry                 C1 
_em_helical_entity.angular_rotation_per_subunit   56.13 
_em_helical_entity.axial_rise_per_subunit         27.3 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         53 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?         ?            
'MODEL REFINEMENT'              ? 2  ? ? ? PHENIX    1.20.1_4487: 
'IMAGE ACQUISITION'             ? 3  ? ? 1 SerialEM  ?            
MASKING                         ? 4  ? ? ? ?         ?            
'CTF CORRECTION'                ? 5  1 ? ? ?         ?            
'LAYERLINE INDEXING'            ? 6  ? ? ? ?         ?            
'DIFFRACTION INDEXING'          ? 7  ? ? ? ?         ?            
'MODEL FITTING'                 ? 8  ? ? ? ?         ?            
OTHER                           ? 9  ? ? ? ?         ?            
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?         ?            
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?         ?            
CLASSIFICATION                  ? 12 1 ? ? ?         ?            
RECONSTRUCTION                  ? 13 1 ? ? cryoSPARC ?            
'VOLUME SELECTION'              ? 14 1 1 1 ?         ?            
'SERIES ALIGNMENT'              ? 15 1 1 1 ?         ?            
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?         ?            
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?         ?            
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?         ?            
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?         ?            
# 
_em_specimen.concentration           0.23 
_em_specimen.details                 
;20 mM HEPES
150 mM NaCl
5 mM betamercaptoethanol
Incubation overnight with 0.004 uM RNA.
Prior freezing, the sample was incubated with 2 mM methyl PEG8 N hydroxysuccinimide ester reagent.
;
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Agence Nationale de la Recherche (ANR)'                          France ANR-23-CE11-01      1 
'Grenoble Alliance for Integrated Structural Cell Biology (GRAL)' France ANR-17-EURE-0003    2 
'Grenoble Instruct-ERIC Center (ISBG)'                            France ANR-10-INSB-0005-02 3 
# 
_atom_sites.entry_id                    9GAS 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    O OP3   . U     A 1 1   ? 271.822 191.031 243.109 1.00 60.21  ? 1   U     D OP3   1 
ATOM   2    P P     . U     A 1 1   ? 270.677 190.302 243.695 1.00 63.66  ? 1   U     D P     1 
ATOM   3    O OP1   . U     A 1 1   ? 269.509 191.211 243.712 1.00 59.90  ? 1   U     D OP1   1 
ATOM   4    O OP2   . U     A 1 1   ? 270.549 189.006 242.992 1.00 64.07  ? 1   U     D OP2   1 
ATOM   5    O "O5'" . U     A 1 1   ? 271.021 189.967 245.211 1.00 59.55  ? 1   U     D "O5'" 1 
ATOM   6    C "C5'" . U     A 1 1   ? 270.140 189.164 245.984 1.00 59.83  ? 1   U     D "C5'" 1 
ATOM   7    C "C4'" . U     A 1 1   ? 270.687 188.868 247.359 1.00 59.57  ? 1   U     D "C4'" 1 
ATOM   8    O "O4'" . U     A 1 1   ? 271.859 188.015 247.249 1.00 60.70  ? 1   U     D "O4'" 1 
ATOM   9    C "C3'" . U     A 1 1   ? 271.117 190.081 248.183 1.00 57.89  ? 1   U     D "C3'" 1 
ATOM   10   O "O3'" . U     A 1 1   ? 270.814 189.841 249.555 1.00 59.88  ? 1   U     D "O3'" 1 
ATOM   11   C "C2'" . U     A 1 1   ? 272.632 190.088 248.003 1.00 58.60  ? 1   U     D "C2'" 1 
ATOM   12   O "O2'" . U     A 1 1   ? 273.341 190.731 249.039 1.00 63.09  ? 1   U     D "O2'" 1 
ATOM   13   C "C1'" . U     A 1 1   ? 272.931 188.595 247.961 1.00 57.25  ? 1   U     D "C1'" 1 
ATOM   14   N N1    . U     A 1 1   ? 274.190 188.232 247.297 1.00 54.73  ? 1   U     D N1    1 
ATOM   15   C C2    . U     A 1 1   ? 275.252 187.936 248.121 1.00 55.56  ? 1   U     D C2    1 
ATOM   16   O O2    . U     A 1 1   ? 275.172 187.985 249.333 1.00 56.66  ? 1   U     D O2    1 
ATOM   17   N N3    . U     A 1 1   ? 276.411 187.590 247.481 1.00 54.72  ? 1   U     D N3    1 
ATOM   18   C C4    . U     A 1 1   ? 276.603 187.505 246.121 1.00 53.63  ? 1   U     D C4    1 
ATOM   19   O O4    . U     A 1 1   ? 277.709 187.179 245.695 1.00 54.08  ? 1   U     D O4    1 
ATOM   20   C C5    . U     A 1 1   ? 275.453 187.822 245.331 1.00 53.38  ? 1   U     D C5    1 
ATOM   21   C C6    . U     A 1 1   ? 274.309 188.163 245.931 1.00 54.79  ? 1   U     D C6    1 
ATOM   22   P P     . C     A 1 2   ? 269.443 190.352 250.225 1.00 63.69  ? 2   C     D P     1 
ATOM   23   O OP1   . C     A 1 2   ? 269.313 189.861 251.654 1.00 61.73  ? 2   C     D OP1   1 
ATOM   24   O OP2   . C     A 1 2   ? 268.214 190.076 249.377 1.00 61.89  ? 2   C     D OP2   1 
ATOM   25   O "O5'" . C     A 1 2   ? 269.607 191.958 250.305 1.00 62.16  ? 2   C     D "O5'" 1 
ATOM   26   C "C5'" . C     A 1 2   ? 270.694 192.508 251.091 1.00 58.99  ? 2   C     D "C5'" 1 
ATOM   27   C "C4'" . C     A 1 2   ? 270.390 193.944 251.440 1.00 60.80  ? 2   C     D "C4'" 1 
ATOM   28   O "O4'" . C     A 1 2   ? 270.361 194.754 250.239 1.00 62.17  ? 2   C     D "O4'" 1 
ATOM   29   C "C3'" . C     A 1 2   ? 269.018 194.206 252.073 1.00 63.40  ? 2   C     D "C3'" 1 
ATOM   30   O "O3'" . C     A 1 2   ? 268.993 193.864 253.456 1.00 64.63  ? 2   C     D "O3'" 1 
ATOM   31   C "C2'" . C     A 1 2   ? 268.845 195.708 251.812 1.00 65.44  ? 2   C     D "C2'" 1 
ATOM   32   O "O2'" . C     A 1 2   ? 269.494 196.510 252.775 1.00 68.75  ? 2   C     D "O2'" 1 
ATOM   33   C "C1'" . C     A 1 2   ? 269.547 195.887 250.459 1.00 63.57  ? 2   C     D "C1'" 1 
ATOM   34   N N1    . C     A 1 2   ? 268.592 196.020 249.326 1.00 64.29  ? 2   C     D N1    1 
ATOM   35   C C2    . C     A 1 2   ? 268.171 197.303 248.966 1.00 63.60  ? 2   C     D C2    1 
ATOM   36   O O2    . C     A 1 2   ? 268.608 198.274 249.602 1.00 65.61  ? 2   C     D O2    1 
ATOM   37   N N3    . C     A 1 2   ? 267.305 197.445 247.934 1.00 61.25  ? 2   C     D N3    1 
ATOM   38   C C4    . C     A 1 2   ? 266.858 196.370 247.273 1.00 63.71  ? 2   C     D C4    1 
ATOM   39   N N4    . C     A 1 2   ? 266.011 196.567 246.274 1.00 63.68  ? 2   C     D N4    1 
ATOM   40   C C5    . C     A 1 2   ? 267.274 195.057 247.628 1.00 64.74  ? 2   C     D C5    1 
ATOM   41   C C6    . C     A 1 2   ? 268.131 194.928 248.651 1.00 63.58  ? 2   C     D C6    1 
ATOM   42   P P     . U     A 1 3   ? 267.616 193.503 254.208 1.00 73.90  ? 3   U     D P     1 
ATOM   43   O OP1   . U     A 1 3   ? 267.926 192.909 255.529 1.00 70.12  ? 3   U     D OP1   1 
ATOM   44   O OP2   . U     A 1 3   ? 266.775 192.755 253.241 1.00 68.10  ? 3   U     D OP2   1 
ATOM   45   O "O5'" . U     A 1 3   ? 266.949 194.932 254.443 1.00 66.52  ? 3   U     D "O5'" 1 
ATOM   46   C "C5'" . U     A 1 3   ? 267.494 195.850 255.378 1.00 61.70  ? 3   U     D "C5'" 1 
ATOM   47   C "C4'" . U     A 1 3   ? 266.901 197.227 255.209 1.00 59.83  ? 3   U     D "C4'" 1 
ATOM   48   O "O4'" . U     A 1 3   ? 267.110 197.683 253.852 1.00 57.05  ? 3   U     D "O4'" 1 
ATOM   49   C "C3'" . U     A 1 3   ? 265.398 197.339 255.410 1.00 60.58  ? 3   U     D "C3'" 1 
ATOM   50   O "O3'" . U     A 1 3   ? 265.040 197.438 256.776 1.00 59.23  ? 3   U     D "O3'" 1 
ATOM   51   C "C2'" . U     A 1 3   ? 265.040 198.579 254.603 1.00 58.30  ? 3   U     D "C2'" 1 
ATOM   52   O "O2'" . U     A 1 3   ? 265.343 199.753 255.339 1.00 58.33  ? 3   U     D "O2'" 1 
ATOM   53   C "C1'" . U     A 1 3   ? 266.025 198.485 253.439 1.00 57.23  ? 3   U     D "C1'" 1 
ATOM   54   N N1    . U     A 1 3   ? 265.439 197.892 252.216 1.00 58.03  ? 3   U     D N1    1 
ATOM   55   C C2    . U     A 1 3   ? 264.970 198.763 251.258 1.00 56.64  ? 3   U     D C2    1 
ATOM   56   O O2    . U     A 1 3   ? 265.001 199.972 251.398 1.00 55.21  ? 3   U     D O2    1 
ATOM   57   N N3    . U     A 1 3   ? 264.460 198.169 250.132 1.00 56.12  ? 3   U     D N3    1 
ATOM   58   C C4    . U     A 1 3   ? 264.379 196.819 249.873 1.00 55.33  ? 3   U     D C4    1 
ATOM   59   O O4    . U     A 1 3   ? 263.891 196.435 248.811 1.00 55.42  ? 3   U     D O4    1 
ATOM   60   C C5    . U     A 1 3   ? 264.892 195.981 250.909 1.00 57.66  ? 3   U     D C5    1 
ATOM   61   C C6    . U     A 1 3   ? 265.394 196.535 252.015 1.00 59.61  ? 3   U     D C6    1 
ATOM   62   P P     . C     A 1 4   ? 263.536 197.134 257.246 1.00 60.58  ? 4   C     D P     1 
ATOM   63   O OP1   . C     A 1 4   ? 263.547 197.054 258.726 1.00 62.21  ? 4   C     D OP1   1 
ATOM   64   O OP2   . C     A 1 4   ? 263.004 195.999 256.450 1.00 57.53  ? 4   C     D OP2   1 
ATOM   65   O "O5'" . C     A 1 4   ? 262.732 198.439 256.822 1.00 56.83  ? 4   C     D "O5'" 1 
ATOM   66   C "C5'" . C     A 1 4   ? 263.000 199.693 257.428 1.00 53.54  ? 4   C     D "C5'" 1 
ATOM   67   C "C4'" . C     A 1 4   ? 262.261 200.802 256.728 1.00 52.16  ? 4   C     D "C4'" 1 
ATOM   68   O "O4'" . C     A 1 4   ? 262.655 200.843 255.335 1.00 53.63  ? 4   C     D "O4'" 1 
ATOM   69   C "C3'" . C     A 1 4   ? 260.749 200.658 256.678 1.00 50.95  ? 4   C     D "C3'" 1 
ATOM   70   O "O3'" . C     A 1 4   ? 260.121 201.077 257.875 1.00 51.98  ? 4   C     D "O3'" 1 
ATOM   71   C "C2'" . C     A 1 4   ? 260.374 201.491 255.461 1.00 50.56  ? 4   C     D "C2'" 1 
ATOM   72   O "O2'" . C     A 1 4   ? 260.366 202.873 255.785 1.00 51.66  ? 4   C     D "O2'" 1 
ATOM   73   C "C1'" . C     A 1 4   ? 261.559 201.223 254.532 1.00 52.68  ? 4   C     D "C1'" 1 
ATOM   74   N N1    . C     A 1 4   ? 261.288 200.142 253.557 1.00 55.84  ? 4   C     D N1    1 
ATOM   75   C C2    . C     A 1 4   ? 260.842 200.494 252.283 1.00 56.77  ? 4   C     D C2    1 
ATOM   76   O O2    . C     A 1 4   ? 260.680 201.692 252.021 1.00 57.23  ? 4   C     D O2    1 
ATOM   77   N N3    . C     A 1 4   ? 260.598 199.523 251.374 1.00 55.42  ? 4   C     D N3    1 
ATOM   78   C C4    . C     A 1 4   ? 260.787 198.245 251.699 1.00 55.26  ? 4   C     D C4    1 
ATOM   79   N N4    . C     A 1 4   ? 260.532 197.319 250.774 1.00 56.16  ? 4   C     D N4    1 
ATOM   80   C C5    . C     A 1 4   ? 261.244 197.855 252.987 1.00 55.19  ? 4   C     D C5    1 
ATOM   81   C C6    . C     A 1 4   ? 261.482 198.827 253.873 1.00 56.53  ? 4   C     D C6    1 
ATOM   82   P P     . U     A 1 5   ? 259.022 200.144 258.581 1.00 55.05  ? 5   U     D P     1 
ATOM   83   O OP1   . U     A 1 5   ? 259.009 200.465 260.028 1.00 54.89  ? 5   U     D OP1   1 
ATOM   84   O OP2   . U     A 1 5   ? 259.237 198.746 258.137 1.00 51.01  ? 5   U     D OP2   1 
ATOM   85   O "O5'" . U     A 1 5   ? 257.648 200.654 257.966 1.00 49.87  ? 5   U     D "O5'" 1 
ATOM   86   C "C5'" . U     A 1 5   ? 257.321 202.032 257.987 1.00 49.61  ? 5   U     D "C5'" 1 
ATOM   87   C "C4'" . U     A 1 5   ? 256.580 202.441 256.744 1.00 49.00  ? 5   U     D "C4'" 1 
ATOM   88   O "O4'" . U     A 1 5   ? 255.251 201.862 256.755 1.00 53.72  ? 5   U     D "O4'" 1 
ATOM   89   C "C3'" . U     A 1 5   ? 256.326 203.930 256.585 1.00 49.97  ? 5   U     D "C3'" 1 
ATOM   90   O "O3'" . U     A 1 5   ? 257.448 204.631 256.082 1.00 52.26  ? 5   U     D "O3'" 1 
ATOM   91   C "C2'" . U     A 1 5   ? 255.122 203.959 255.658 1.00 51.56  ? 5   U     D "C2'" 1 
ATOM   92   O "O2'" . U     A 1 5   ? 255.516 203.706 254.319 1.00 55.37  ? 5   U     D "O2'" 1 
ATOM   93   C "C1'" . U     A 1 5   ? 254.332 202.754 256.162 1.00 51.42  ? 5   U     D "C1'" 1 
ATOM   94   N N1    . U     A 1 5   ? 253.291 203.145 257.146 1.00 51.42  ? 5   U     D N1    1 
ATOM   95   C C2    . U     A 1 5   ? 253.326 202.775 258.487 1.00 51.63  ? 5   U     D C2    1 
ATOM   96   O O2    . U     A 1 5   ? 254.193 202.109 259.022 1.00 53.97  ? 5   U     D O2    1 
ATOM   97   N N3    . U     A 1 5   ? 252.271 203.226 259.237 1.00 49.50  ? 5   U     D N3    1 
ATOM   98   C C4    . U     A 1 5   ? 251.204 203.987 258.817 1.00 51.77  ? 5   U     D C4    1 
ATOM   99   O O4    . U     A 1 5   ? 250.335 204.310 259.624 1.00 54.24  ? 5   U     D O4    1 
ATOM   100  C C5    . U     A 1 5   ? 251.231 204.326 257.433 1.00 51.14  ? 5   U     D C5    1 
ATOM   101  C C6    . U     A 1 5   ? 252.244 203.903 256.676 1.00 51.22  ? 5   U     D C6    1 
ATOM   102  P P     . C     A 1 6   ? 257.969 205.958 256.821 1.00 55.09  ? 6   C     D P     1 
ATOM   103  O OP1   . C     A 1 6   ? 259.145 206.454 256.067 1.00 55.77  ? 6   C     D OP1   1 
ATOM   104  O OP2   . C     A 1 6   ? 258.094 205.681 258.273 1.00 55.60  ? 6   C     D OP2   1 
ATOM   105  O "O5'" . C     A 1 6   ? 256.776 206.993 256.632 1.00 52.02  ? 6   C     D "O5'" 1 
ATOM   106  C "C5'" . C     A 1 6   ? 256.279 207.297 255.340 1.00 48.78  ? 6   C     D "C5'" 1 
ATOM   107  C "C4'" . C     A 1 6   ? 254.953 208.009 255.412 1.00 51.33  ? 6   C     D "C4'" 1 
ATOM   108  O "O4'" . C     A 1 6   ? 253.953 207.159 256.028 1.00 53.79  ? 6   C     D "O4'" 1 
ATOM   109  C "C3'" . C     A 1 6   ? 254.918 209.274 256.248 1.00 53.64  ? 6   C     D "C3'" 1 
ATOM   110  O "O3'" . C     A 1 6   ? 255.465 210.393 255.580 1.00 56.03  ? 6   C     D "O3'" 1 
ATOM   111  C "C2'" . C     A 1 6   ? 253.436 209.414 256.564 1.00 52.90  ? 6   C     D "C2'" 1 
ATOM   112  O "O2'" . C     A 1 6   ? 252.734 209.931 255.444 1.00 53.41  ? 6   C     D "O2'" 1 
ATOM   113  C "C1'" . C     A 1 6   ? 253.031 207.952 256.748 1.00 51.70  ? 6   C     D "C1'" 1 
ATOM   114  N N1    . C     A 1 6   ? 253.059 207.540 258.168 1.00 51.46  ? 6   C     D N1    1 
ATOM   115  C C2    . C     A 1 6   ? 251.992 207.897 258.990 1.00 50.09  ? 6   C     D C2    1 
ATOM   116  O O2    . C     A 1 6   ? 251.058 208.550 258.506 1.00 48.97  ? 6   C     D O2    1 
ATOM   117  N N3    . C     A 1 6   ? 252.001 207.522 260.289 1.00 49.22  ? 6   C     D N3    1 
ATOM   118  C C4    . C     A 1 6   ? 253.025 206.821 260.770 1.00 49.57  ? 6   C     D C4    1 
ATOM   119  N N4    . C     A 1 6   ? 252.995 206.473 262.057 1.00 51.07  ? 6   C     D N4    1 
ATOM   120  C C5    . C     A 1 6   ? 254.126 206.440 259.955 1.00 49.21  ? 6   C     D C5    1 
ATOM   121  C C6    . C     A 1 6   ? 254.101 206.817 258.673 1.00 50.57  ? 6   C     D C6    1 
ATOM   122  P P     . U     A 1 7   ? 256.627 211.255 256.274 1.00 60.71  ? 7   U     D P     1 
ATOM   123  O OP1   . U     A 1 7   ? 257.755 210.353 256.608 1.00 59.74  ? 7   U     D OP1   1 
ATOM   124  O OP2   . U     A 1 7   ? 256.000 212.067 257.346 1.00 57.30  ? 7   U     D OP2   1 
ATOM   125  O "O5'" . U     A 1 7   ? 257.128 212.227 255.117 1.00 60.01  ? 7   U     D "O5'" 1 
ATOM   126  C "C5'" . U     A 1 7   ? 258.194 213.138 255.351 1.00 62.28  ? 7   U     D "C5'" 1 
ATOM   127  C "C4'" . U     A 1 7   ? 258.593 213.875 254.098 1.00 64.69  ? 7   U     D "C4'" 1 
ATOM   128  O "O4'" . U     A 1 7   ? 257.395 214.289 253.389 1.00 66.62  ? 7   U     D "O4'" 1 
ATOM   129  C "C3'" . U     A 1 7   ? 259.406 215.144 254.334 1.00 62.96  ? 7   U     D "C3'" 1 
ATOM   130  O "O3'" . U     A 1 7   ? 260.307 215.339 253.246 1.00 58.97  ? 7   U     D "O3'" 1 
ATOM   131  C "C2'" . U     A 1 7   ? 258.337 216.229 254.312 1.00 69.18  ? 7   U     D "C2'" 1 
ATOM   132  O "O2'" . U     A 1 7   ? 258.817 217.517 253.991 1.00 73.20  ? 7   U     D "O2'" 1 
ATOM   133  C "C1'" . U     A 1 7   ? 257.388 215.696 253.244 1.00 68.88  ? 7   U     D "C1'" 1 
ATOM   134  N N1    . U     A 1 7   ? 256.000 216.158 253.374 1.00 68.43  ? 7   U     D N1    1 
ATOM   135  C C2    . U     A 1 7   ? 255.659 217.377 252.824 1.00 69.86  ? 7   U     D C2    1 
ATOM   136  O O2    . U     A 1 7   ? 256.459 218.097 252.255 1.00 73.17  ? 7   U     D O2    1 
ATOM   137  N N3    . U     A 1 7   ? 254.346 217.733 252.976 1.00 69.75  ? 7   U     D N3    1 
ATOM   138  C C4    . U     A 1 7   ? 253.357 217.005 253.599 1.00 75.04  ? 7   U     D C4    1 
ATOM   139  O O4    . U     A 1 7   ? 252.215 217.460 253.656 1.00 81.51  ? 7   U     D O4    1 
ATOM   140  C C5    . U     A 1 7   ? 253.786 215.751 254.133 1.00 71.37  ? 7   U     D C5    1 
ATOM   141  C C6    . U     A 1 7   ? 255.061 215.380 254.001 1.00 68.62  ? 7   U     D C6    1 
ATOM   142  P P     . C     B 1 2   ? 235.960 195.117 227.114 1.00 114.37 ? 8   C     C P     1 
ATOM   143  O OP1   . C     B 1 2   ? 236.542 194.740 225.801 1.00 121.90 ? 8   C     C OP1   1 
ATOM   144  O OP2   . C     B 1 2   ? 235.055 194.173 227.815 1.00 115.70 ? 8   C     C OP2   1 
ATOM   145  O "O5'" . C     B 1 2   ? 237.167 195.451 228.096 1.00 118.32 ? 8   C     C "O5'" 1 
ATOM   146  C "C5'" . C     B 1 2   ? 237.796 194.423 228.851 1.00 120.02 ? 8   C     C "C5'" 1 
ATOM   147  C "C4'" . C     B 1 2   ? 238.439 194.964 230.102 1.00 120.09 ? 8   C     C "C4'" 1 
ATOM   148  O "O4'" . C     B 1 2   ? 237.459 195.749 230.832 1.00 124.47 ? 8   C     C "O4'" 1 
ATOM   149  C "C3'" . C     B 1 2   ? 238.945 193.904 231.076 1.00 119.45 ? 8   C     C "C3'" 1 
ATOM   150  O "O3'" . C     B 1 2   ? 240.096 194.395 231.758 1.00 122.38 ? 8   C     C "O3'" 1 
ATOM   151  C "C2'" . C     B 1 2   ? 237.788 193.774 232.058 1.00 122.01 ? 8   C     C "C2'" 1 
ATOM   152  O "O2'" . C     B 1 2   ? 238.151 193.283 233.330 1.00 124.74 ? 8   C     C "O2'" 1 
ATOM   153  C "C1'" . C     B 1 2   ? 237.286 195.213 232.130 1.00 128.16 ? 8   C     C "C1'" 1 
ATOM   154  N N1    . C     B 1 2   ? 235.865 195.331 232.483 1.00 132.15 ? 8   C     C N1    1 
ATOM   155  C C2    . C     B 1 2   ? 235.510 195.990 233.661 1.00 132.28 ? 8   C     C C2    1 
ATOM   156  O O2    . C     B 1 2   ? 236.407 196.455 234.378 1.00 132.02 ? 8   C     C O2    1 
ATOM   157  N N3    . C     B 1 2   ? 234.204 196.102 233.988 1.00 132.09 ? 8   C     C N3    1 
ATOM   158  C C4    . C     B 1 2   ? 233.272 195.588 233.186 1.00 133.38 ? 8   C     C C4    1 
ATOM   159  N N4    . C     B 1 2   ? 231.993 195.720 233.546 1.00 132.91 ? 8   C     C N4    1 
ATOM   160  C C5    . C     B 1 2   ? 233.605 194.912 231.978 1.00 131.54 ? 8   C     C C5    1 
ATOM   161  C C6    . C     B 1 2   ? 234.902 194.807 231.668 1.00 130.56 ? 8   C     C C6    1 
ATOM   162  P P     . U     B 1 3   ? 241.544 193.775 231.446 1.00 127.99 ? 9   U     C P     1 
ATOM   163  O OP1   . U     B 1 3   ? 242.374 193.909 232.668 1.00 127.45 ? 9   U     C OP1   1 
ATOM   164  O OP2   . U     B 1 3   ? 242.025 194.353 230.167 1.00 122.33 ? 9   U     C OP2   1 
ATOM   165  O "O5'" . U     B 1 3   ? 241.259 192.226 231.215 1.00 125.18 ? 9   U     C "O5'" 1 
ATOM   166  C "C5'" . U     B 1 3   ? 241.129 191.338 232.316 1.00 123.20 ? 9   U     C "C5'" 1 
ATOM   167  C "C4'" . U     B 1 3   ? 241.053 189.905 231.857 1.00 117.28 ? 9   U     C "C4'" 1 
ATOM   168  O "O4'" . U     B 1 3   ? 239.878 189.721 231.030 1.00 114.43 ? 9   U     C "O4'" 1 
ATOM   169  C "C3'" . U     B 1 3   ? 242.206 189.432 230.987 1.00 118.85 ? 9   U     C "C3'" 1 
ATOM   170  O "O3'" . U     B 1 3   ? 243.326 189.021 231.752 1.00 118.61 ? 9   U     C "O3'" 1 
ATOM   171  C "C2'" . U     B 1 3   ? 241.584 188.300 230.181 1.00 119.36 ? 9   U     C "C2'" 1 
ATOM   172  O "O2'" . U     B 1 3   ? 241.553 187.104 230.943 1.00 116.00 ? 9   U     C "O2'" 1 
ATOM   173  C "C1'" . U     B 1 3   ? 240.147 188.794 230.004 1.00 116.35 ? 9   U     C "C1'" 1 
ATOM   174  N N1    . U     B 1 3   ? 239.901 189.455 228.701 1.00 114.90 ? 9   U     C N1    1 
ATOM   175  C C2    . U     B 1 3   ? 240.015 188.734 227.524 1.00 117.20 ? 9   U     C C2    1 
ATOM   176  O O2    . U     B 1 3   ? 240.346 187.564 227.470 1.00 120.00 ? 9   U     C O2    1 
ATOM   177  N N3    . U     B 1 3   ? 239.741 189.445 226.383 1.00 114.35 ? 9   U     C N3    1 
ATOM   178  C C4    . U     B 1 3   ? 239.358 190.763 226.292 1.00 113.30 ? 9   U     C C4    1 
ATOM   179  O O4    . U     B 1 3   ? 239.146 191.259 225.186 1.00 117.24 ? 9   U     C O4    1 
ATOM   180  C C5    . U     B 1 3   ? 239.247 191.433 227.548 1.00 113.81 ? 9   U     C C5    1 
ATOM   181  C C6    . U     B 1 3   ? 239.508 190.770 228.677 1.00 114.07 ? 9   U     C C6    1 
ATOM   182  P P     . C     B 1 4   ? 244.770 189.673 231.494 1.00 130.30 ? 10  C     C P     1 
ATOM   183  O OP1   . C     B 1 4   ? 245.717 189.052 232.452 1.00 129.42 ? 10  C     C OP1   1 
ATOM   184  O OP2   . C     B 1 4   ? 244.618 191.149 231.460 1.00 129.55 ? 10  C     C OP2   1 
ATOM   185  O "O5'" . C     B 1 4   ? 245.163 189.178 230.034 1.00 127.16 ? 10  C     C "O5'" 1 
ATOM   186  C "C5'" . C     B 1 4   ? 245.535 187.829 229.798 1.00 123.53 ? 10  C     C "C5'" 1 
ATOM   187  C "C4'" . C     B 1 4   ? 245.577 187.523 228.323 1.00 119.01 ? 10  C     C "C4'" 1 
ATOM   188  O "O4'" . C     B 1 4   ? 244.324 187.918 227.712 1.00 116.69 ? 10  C     C "O4'" 1 
ATOM   189  C "C3'" . C     B 1 4   ? 246.631 188.266 227.519 1.00 117.73 ? 10  C     C "C3'" 1 
ATOM   190  O "O3'" . C     B 1 4   ? 247.908 187.661 227.603 1.00 122.44 ? 10  C     C "O3'" 1 
ATOM   191  C "C2'" . C     B 1 4   ? 246.049 188.258 226.113 1.00 116.44 ? 10  C     C "C2'" 1 
ATOM   192  O "O2'" . C     B 1 4   ? 246.285 187.007 225.484 1.00 119.94 ? 10  C     C "O2'" 1 
ATOM   193  C "C1'" . C     B 1 4   ? 244.552 188.381 226.400 1.00 115.15 ? 10  C     C "C1'" 1 
ATOM   194  N N1    . C     B 1 4   ? 244.062 189.773 226.298 1.00 114.87 ? 10  C     C N1    1 
ATOM   195  C C2    . C     B 1 4   ? 243.755 190.287 225.038 1.00 114.86 ? 10  C     C C2    1 
ATOM   196  O O2    . C     B 1 4   ? 243.915 189.568 224.042 1.00 114.92 ? 10  C     C O2    1 
ATOM   197  N N3    . C     B 1 4   ? 243.298 191.554 224.933 1.00 111.39 ? 10  C     C N3    1 
ATOM   198  C C4    . C     B 1 4   ? 243.140 192.297 226.027 1.00 110.99 ? 10  C     C C4    1 
ATOM   199  N N4    . C     B 1 4   ? 242.686 193.542 225.877 1.00 105.60 ? 10  C     C N4    1 
ATOM   200  C C5    . C     B 1 4   ? 243.439 191.797 227.325 1.00 115.78 ? 10  C     C C5    1 
ATOM   201  C C6    . C     B 1 4   ? 243.891 190.540 227.413 1.00 115.32 ? 10  C     C C6    1 
ATOM   202  P P     . U     B 1 5   ? 249.205 188.553 227.913 1.00 129.54 ? 11  U     C P     1 
ATOM   203  O OP1   . U     B 1 5   ? 250.206 187.685 228.580 1.00 126.40 ? 11  U     C OP1   1 
ATOM   204  O OP2   . U     B 1 5   ? 248.760 189.801 228.581 1.00 129.04 ? 11  U     C OP2   1 
ATOM   205  O "O5'" . U     B 1 5   ? 249.765 188.930 226.470 1.00 128.53 ? 11  U     C "O5'" 1 
ATOM   206  C "C5'" . U     B 1 5   ? 250.497 187.984 225.705 1.00 131.37 ? 11  U     C "C5'" 1 
ATOM   207  C "C4'" . U     B 1 5   ? 250.845 188.530 224.344 1.00 131.15 ? 11  U     C "C4'" 1 
ATOM   208  O "O4'" . U     B 1 5   ? 249.642 188.642 223.546 1.00 129.63 ? 11  U     C "O4'" 1 
ATOM   209  C "C3'" . U     B 1 5   ? 251.440 189.930 224.326 1.00 130.34 ? 11  U     C "C3'" 1 
ATOM   210  O "O3'" . U     B 1 5   ? 252.835 189.928 224.571 1.00 130.08 ? 11  U     C "O3'" 1 
ATOM   211  C "C2'" . U     B 1 5   ? 251.075 190.439 222.937 1.00 132.51 ? 11  U     C "C2'" 1 
ATOM   212  O "O2'" . U     B 1 5   ? 251.987 189.947 221.967 1.00 134.06 ? 11  U     C "O2'" 1 
ATOM   213  C "C1'" . U     B 1 5   ? 249.720 189.772 222.707 1.00 130.95 ? 11  U     C "C1'" 1 
ATOM   214  N N1    . U     B 1 5   ? 248.568 190.653 223.002 1.00 129.02 ? 11  U     C N1    1 
ATOM   215  C C2    . U     B 1 5   ? 248.145 191.518 222.016 1.00 131.05 ? 11  U     C C2    1 
ATOM   216  O O2    . U     B 1 5   ? 248.698 191.609 220.934 1.00 132.92 ? 11  U     C O2    1 
ATOM   217  N N3    . U     B 1 5   ? 247.055 192.283 222.346 1.00 129.70 ? 11  U     C N3    1 
ATOM   218  C C4    . U     B 1 5   ? 246.355 192.262 223.534 1.00 125.88 ? 11  U     C C4    1 
ATOM   219  O O4    . U     B 1 5   ? 245.391 193.014 223.682 1.00 126.25 ? 11  U     C O4    1 
ATOM   220  C C5    . U     B 1 5   ? 246.850 191.333 224.498 1.00 125.46 ? 11  U     C C5    1 
ATOM   221  C C6    . U     B 1 5   ? 247.909 190.574 224.203 1.00 126.96 ? 11  U     C C6    1 
ATOM   222  P P     . C     B 1 6   ? 253.420 190.522 225.943 1.00 141.19 ? 12  C     C P     1 
ATOM   223  O OP1   . C     B 1 6   ? 254.901 190.461 225.862 1.00 139.77 ? 12  C     C OP1   1 
ATOM   224  O OP2   . C     B 1 6   ? 252.722 189.867 227.077 1.00 137.89 ? 12  C     C OP2   1 
ATOM   225  O "O5'" . C     B 1 6   ? 252.988 192.053 225.910 1.00 141.55 ? 12  C     C "O5'" 1 
ATOM   226  C "C5'" . C     B 1 6   ? 253.758 193.015 225.197 1.00 135.76 ? 12  C     C "C5'" 1 
ATOM   227  C "C4'" . C     B 1 6   ? 253.181 193.280 223.830 1.00 133.92 ? 12  C     C "C4'" 1 
ATOM   228  O "O4'" . C     B 1 6   ? 251.732 193.253 223.916 1.00 133.20 ? 12  C     C "O4'" 1 
ATOM   229  C "C3'" . C     B 1 6   ? 253.545 194.630 223.219 1.00 134.35 ? 12  C     C "C3'" 1 
ATOM   230  O "O3'" . C     B 1 6   ? 253.636 194.500 221.801 1.00 138.60 ? 12  C     C "O3'" 1 
ATOM   231  C "C2'" . C     B 1 6   ? 252.337 195.490 223.573 1.00 132.91 ? 12  C     C "C2'" 1 
ATOM   232  O "O2'" . C     B 1 6   ? 252.137 196.600 222.725 1.00 132.38 ? 12  C     C "O2'" 1 
ATOM   233  C "C1'" . C     B 1 6   ? 251.203 194.478 223.455 1.00 133.71 ? 12  C     C "C1'" 1 
ATOM   234  N N1    . C     B 1 6   ? 250.017 194.787 224.266 1.00 136.00 ? 12  C     C N1    1 
ATOM   235  C C2    . C     B 1 6   ? 249.034 195.628 223.744 1.00 138.96 ? 12  C     C C2    1 
ATOM   236  O O2    . C     B 1 6   ? 249.201 196.116 222.616 1.00 139.22 ? 12  C     C O2    1 
ATOM   237  N N3    . C     B 1 6   ? 247.937 195.900 224.487 1.00 141.89 ? 12  C     C N3    1 
ATOM   238  C C4    . C     B 1 6   ? 247.799 195.355 225.697 1.00 139.37 ? 12  C     C C4    1 
ATOM   239  N N4    . C     B 1 6   ? 246.700 195.650 226.395 1.00 137.71 ? 12  C     C N4    1 
ATOM   240  C C5    . C     B 1 6   ? 248.780 194.482 226.248 1.00 135.63 ? 12  C     C C5    1 
ATOM   241  C C6    . C     B 1 6   ? 249.860 194.225 225.502 1.00 135.11 ? 12  C     C C6    1 
ATOM   242  P P     . U     B 1 7   ? 254.810 193.630 221.127 1.00 147.91 ? 13  U     C P     1 
ATOM   243  O OP1   . U     B 1 7   ? 255.348 194.400 219.978 1.00 142.38 ? 13  U     C OP1   1 
ATOM   244  O OP2   . U     B 1 7   ? 254.297 192.253 220.912 1.00 146.06 ? 13  U     C OP2   1 
ATOM   245  O "O5'" . U     B 1 7   ? 255.948 193.561 222.240 1.00 136.90 ? 13  U     C "O5'" 1 
ATOM   246  C "C5'" . U     B 1 7   ? 257.056 194.448 222.209 1.00 131.74 ? 13  U     C "C5'" 1 
ATOM   247  C "C4'" . U     B 1 7   ? 256.989 195.432 223.347 1.00 131.08 ? 13  U     C "C4'" 1 
ATOM   248  O "O4'" . U     B 1 7   ? 256.724 194.727 224.583 1.00 129.36 ? 13  U     C "O4'" 1 
ATOM   249  C "C3'" . U     B 1 7   ? 258.252 196.232 223.633 1.00 127.25 ? 13  U     C "C3'" 1 
ATOM   250  O "O3'" . U     B 1 7   ? 258.405 197.331 222.744 1.00 126.38 ? 13  U     C "O3'" 1 
ATOM   251  C "C2'" . U     B 1 7   ? 258.086 196.615 225.103 1.00 125.05 ? 13  U     C "C2'" 1 
ATOM   252  O "O2'" . U     B 1 7   ? 257.259 197.762 225.236 1.00 117.68 ? 13  U     C "O2'" 1 
ATOM   253  C "C1'" . U     B 1 7   ? 257.324 195.406 225.661 1.00 128.36 ? 13  U     C "C1'" 1 
ATOM   254  N N1    . U     B 1 7   ? 258.142 194.455 226.459 1.00 126.78 ? 13  U     C N1    1 
ATOM   255  C C2    . U     B 1 7   ? 259.407 193.999 226.096 1.00 126.70 ? 13  U     C C2    1 
ATOM   256  O O2    . U     B 1 7   ? 260.013 194.287 225.080 1.00 126.34 ? 13  U     C O2    1 
ATOM   257  N N3    . U     B 1 7   ? 259.979 193.124 226.987 1.00 127.48 ? 13  U     C N3    1 
ATOM   258  C C4    . U     B 1 7   ? 259.462 192.667 228.177 1.00 124.99 ? 13  U     C C4    1 
ATOM   259  O O4    . U     B 1 7   ? 260.115 191.881 228.865 1.00 123.86 ? 13  U     C O4    1 
ATOM   260  C C5    . U     B 1 7   ? 258.169 193.180 228.488 1.00 125.87 ? 13  U     C C5    1 
ATOM   261  C C6    . U     B 1 7   ? 257.582 194.029 227.642 1.00 126.92 ? 13  U     C C6    1 
ATOM   262  P P     . C     B 1 8   ? 259.301 198.615 223.118 1.00 123.53 ? 14  C     C P     1 
ATOM   263  O OP1   . C     B 1 8   ? 258.502 199.492 224.009 1.00 115.65 ? 14  C     C OP1   1 
ATOM   264  O OP2   . C     B 1 8   ? 259.832 199.169 221.848 1.00 125.59 ? 14  C     C OP2   1 
ATOM   265  O "O5'" . C     B 1 8   ? 260.539 198.034 223.933 1.00 115.52 ? 14  C     C "O5'" 1 
ATOM   266  C "C5'" . C     B 1 8   ? 261.464 198.910 224.561 1.00 111.53 ? 14  C     C "C5'" 1 
ATOM   267  C "C4'" . C     B 1 8   ? 261.002 199.284 225.945 1.00 105.84 ? 14  C     C "C4'" 1 
ATOM   268  O "O4'" . C     B 1 8   ? 260.861 198.086 226.746 1.00 101.77 ? 14  C     C "O4'" 1 
ATOM   269  C "C3'" . C     B 1 8   ? 261.936 200.167 226.759 1.00 100.95 ? 14  C     C "C3'" 1 
ATOM   270  O "O3'" . C     B 1 8   ? 261.833 201.538 226.409 1.00 100.12 ? 14  C     C "O3'" 1 
ATOM   271  C "C2'" . C     B 1 8   ? 261.522 199.851 228.191 1.00 100.09 ? 14  C     C "C2'" 1 
ATOM   272  O "O2'" . C     B 1 8   ? 260.334 200.549 228.536 1.00 104.84 ? 14  C     C "O2'" 1 
ATOM   273  C "C1'" . C     B 1 8   ? 261.189 198.361 228.090 1.00 101.06 ? 14  C     C "C1'" 1 
ATOM   274  N N1    . C     B 1 8   ? 262.328 197.498 228.479 1.00 100.71 ? 14  C     C N1    1 
ATOM   275  C C2    . C     B 1 8   ? 262.103 196.124 228.569 1.00 105.24 ? 14  C     C C2    1 
ATOM   276  O O2    . C     B 1 8   ? 260.977 195.685 228.291 1.00 110.08 ? 14  C     C O2    1 
ATOM   277  N N3    . C     B 1 8   ? 263.117 195.304 228.925 1.00 97.64  ? 14  C     C N3    1 
ATOM   278  C C4    . C     B 1 8   ? 264.312 195.815 229.209 1.00 92.50  ? 14  C     C C4    1 
ATOM   279  N N4    . C     B 1 8   ? 265.286 194.977 229.564 1.00 95.09  ? 14  C     C N4    1 
ATOM   280  C C5    . C     B 1 8   ? 264.564 197.212 229.145 1.00 91.59  ? 14  C     C C5    1 
ATOM   281  C C6    . C     B 1 8   ? 263.555 198.010 228.785 1.00 95.27  ? 14  C     C C6    1 
ATOM   282  P P     . U     B 1 9   ? 262.250 202.694 227.445 1.00 88.60  ? 15  U     C P     1 
ATOM   283  O OP1   . U     B 1 9   ? 263.458 202.276 228.193 1.00 95.79  ? 15  U     C OP1   1 
ATOM   284  O OP2   . U     B 1 9   ? 261.024 203.093 228.178 1.00 80.93  ? 15  U     C OP2   1 
ATOM   285  O "O5'" . U     B 1 9   ? 262.682 203.910 226.514 1.00 84.83  ? 15  U     C "O5'" 1 
ATOM   286  C "C5'" . U     B 1 9   ? 263.736 203.770 225.573 1.00 83.31  ? 15  U     C "C5'" 1 
ATOM   287  C "C4'" . U     B 1 9   ? 264.871 204.718 225.865 1.00 82.08  ? 15  U     C "C4'" 1 
ATOM   288  O "O4'" . U     B 1 9   ? 264.342 206.005 226.278 1.00 84.51  ? 15  U     C "O4'" 1 
ATOM   289  C "C3'" . U     B 1 9   ? 265.799 204.318 227.001 1.00 79.33  ? 15  U     C "C3'" 1 
ATOM   290  O "O3'" . U     B 1 9   ? 266.779 203.377 226.598 1.00 84.70  ? 15  U     C "O3'" 1 
ATOM   291  C "C2'" . U     B 1 9   ? 266.382 205.655 227.439 1.00 78.14  ? 15  U     C "C2'" 1 
ATOM   292  O "O2'" . U     B 1 9   ? 267.407 206.068 226.549 1.00 76.31  ? 15  U     C "O2'" 1 
ATOM   293  C "C1'" . U     B 1 9   ? 265.184 206.584 227.253 1.00 78.22  ? 15  U     C "C1'" 1 
ATOM   294  N N1    . U     B 1 9   ? 264.407 206.756 228.502 1.00 81.70  ? 15  U     C N1    1 
ATOM   295  C C2    . U     B 1 9   ? 264.890 207.616 229.468 1.00 77.50  ? 15  U     C C2    1 
ATOM   296  O O2    . U     B 1 9   ? 265.930 208.239 229.345 1.00 69.37  ? 15  U     C O2    1 
ATOM   297  N N3    . U     B 1 9   ? 264.105 207.716 230.590 1.00 78.81  ? 15  U     C N3    1 
ATOM   298  C C4    . U     B 1 9   ? 262.915 207.061 230.838 1.00 74.81  ? 15  U     C C4    1 
ATOM   299  O O4    . U     B 1 9   ? 262.321 207.250 231.899 1.00 71.92  ? 15  U     C O4    1 
ATOM   300  C C5    . U     B 1 9   ? 262.484 206.193 229.792 1.00 77.14  ? 15  U     C C5    1 
ATOM   301  C C6    . U     B 1 9   ? 263.227 206.079 228.690 1.00 84.05  ? 15  U     C C6    1 
ATOM   302  P P     . C     B 1 10  ? 267.264 202.215 227.596 1.00 91.30  ? 16  C     C P     1 
ATOM   303  O OP1   . C     B 1 10  ? 268.300 201.431 226.881 1.00 85.25  ? 16  C     C OP1   1 
ATOM   304  O OP2   . C     B 1 10  ? 266.081 201.509 228.139 1.00 95.08  ? 16  C     C OP2   1 
ATOM   305  O "O5'" . C     B 1 10  ? 267.980 203.001 228.782 1.00 82.79  ? 16  C     C "O5'" 1 
ATOM   306  C "C5'" . C     B 1 10  ? 269.188 203.714 228.550 1.00 83.60  ? 16  C     C "C5'" 1 
ATOM   307  C "C4'" . C     B 1 10  ? 269.864 204.123 229.835 1.00 88.50  ? 16  C     C "C4'" 1 
ATOM   308  O "O4'" . C     B 1 10  ? 269.053 205.119 230.517 1.00 86.51  ? 16  C     C "O4'" 1 
ATOM   309  C "C3'" . C     B 1 10  ? 270.101 202.997 230.843 1.00 93.15  ? 16  C     C "C3'" 1 
ATOM   310  O "O3'" . C     B 1 10  ? 271.362 203.172 231.482 1.00 96.34  ? 16  C     C "O3'" 1 
ATOM   311  C "C2'" . C     B 1 10  ? 268.990 203.211 231.864 1.00 94.18  ? 16  C     C "C2'" 1 
ATOM   312  O "O2'" . C     B 1 10  ? 269.280 202.723 233.156 1.00 96.55  ? 16  C     C "O2'" 1 
ATOM   313  C "C1'" . C     B 1 10  ? 268.857 204.726 231.857 1.00 88.65  ? 16  C     C "C1'" 1 
ATOM   314  N N1    . C     B 1 10  ? 267.545 205.200 232.308 1.00 86.75  ? 16  C     C N1    1 
ATOM   315  C C2    . C     B 1 10  ? 267.499 206.133 233.340 1.00 86.81  ? 16  C     C C2    1 
ATOM   316  O O2    . C     B 1 10  ? 268.565 206.542 233.819 1.00 95.16  ? 16  C     C O2    1 
ATOM   317  N N3    . C     B 1 10  ? 266.301 206.572 233.781 1.00 82.58  ? 16  C     C N3    1 
ATOM   318  C C4    . C     B 1 10  ? 265.184 206.102 233.232 1.00 84.68  ? 16  C     C C4    1 
ATOM   319  N N4    . C     B 1 10  ? 264.022 206.562 233.698 1.00 87.60  ? 16  C     C N4    1 
ATOM   320  C C5    . C     B 1 10  ? 265.204 205.140 232.183 1.00 85.18  ? 16  C     C C5    1 
ATOM   321  C C6    . C     B 1 10  ? 266.397 204.716 231.756 1.00 87.45  ? 16  C     C C6    1 
ATOM   322  P P     . U     B 1 11  ? 272.192 201.887 231.971 1.00 106.78 ? 17  U     C P     1 
ATOM   323  O OP1   . U     B 1 11  ? 273.361 202.364 232.749 1.00 106.91 ? 17  U     C OP1   1 
ATOM   324  O OP2   . U     B 1 11  ? 272.401 201.000 230.800 1.00 103.91 ? 17  U     C OP2   1 
ATOM   325  O "O5'" . U     B 1 11  ? 271.196 201.143 232.967 1.00 99.85  ? 17  U     C "O5'" 1 
ATOM   326  C "C5'" . U     B 1 11  ? 270.602 199.903 232.614 1.00 95.02  ? 17  U     C "C5'" 1 
ATOM   327  C "C4'" . U     B 1 11  ? 270.180 199.127 233.835 1.00 98.64  ? 17  U     C "C4'" 1 
ATOM   328  O "O4'" . U     B 1 11  ? 271.322 198.947 234.713 1.00 101.72 ? 17  U     C "O4'" 1 
ATOM   329  C "C3'" . U     B 1 11  ? 269.138 199.784 234.726 1.00 100.92 ? 17  U     C "C3'" 1 
ATOM   330  O "O3'" . U     B 1 11  ? 267.813 199.635 234.251 1.00 100.79 ? 17  U     C "O3'" 1 
ATOM   331  C "C2'" . U     B 1 11  ? 269.380 199.107 236.065 1.00 104.07 ? 17  U     C "C2'" 1 
ATOM   332  O "O2'" . U     B 1 11  ? 268.821 197.803 236.073 1.00 106.77 ? 17  U     C "O2'" 1 
ATOM   333  C "C1'" . U     B 1 11  ? 270.902 198.980 236.061 1.00 102.00 ? 17  U     C "C1'" 1 
ATOM   334  N N1    . U     B 1 11  ? 271.544 200.132 236.730 1.00 99.43  ? 17  U     C N1    1 
ATOM   335  C C2    . U     B 1 11  ? 271.548 200.136 238.107 1.00 109.54 ? 17  U     C C2    1 
ATOM   336  O O2    . U     B 1 11  ? 271.058 199.240 238.769 1.00 113.30 ? 17  U     C O2    1 
ATOM   337  N N3    . U     B 1 11  ? 272.149 201.227 238.681 1.00 114.04 ? 17  U     C N3    1 
ATOM   338  C C4    . U     B 1 11  ? 272.732 202.292 238.030 1.00 112.84 ? 17  U     C C4    1 
ATOM   339  O O4    . U     B 1 11  ? 273.235 203.201 238.690 1.00 119.60 ? 17  U     C O4    1 
ATOM   340  C C5    . U     B 1 11  ? 272.686 202.214 236.605 1.00 107.24 ? 17  U     C C5    1 
ATOM   341  C C6    . U     B 1 11  ? 272.108 201.163 236.020 1.00 101.68 ? 17  U     C C6    1 
ATOM   342  P P     . C     B 1 12  ? 266.587 200.266 235.077 1.00 108.92 ? 18  C     C P     1 
ATOM   343  O OP1   . C     B 1 12  ? 266.118 199.236 236.086 1.00 107.80 ? 18  C     C OP1   1 
ATOM   344  O "O5'" . C     B 1 12  ? 267.244 201.474 235.879 1.00 106.89 ? 18  C     C "O5'" 1 
ATOM   345  C "C5'" . C     B 1 12  ? 266.481 202.258 236.784 1.00 107.43 ? 18  C     C "C5'" 1 
ATOM   346  C "C4'" . C     B 1 12  ? 266.971 202.091 238.200 1.00 114.73 ? 18  C     C "C4'" 1 
ATOM   347  O "O4'" . C     B 1 12  ? 268.422 202.146 238.219 1.00 117.16 ? 18  C     C "O4'" 1 
ATOM   348  C "C3'" . C     B 1 12  ? 266.559 203.181 239.177 1.00 121.23 ? 18  C     C "C3'" 1 
ATOM   349  O "O3'" . C     B 1 12  ? 265.246 203.026 239.684 1.00 125.40 ? 18  C     C "O3'" 1 
ATOM   350  C "C2'" . C     B 1 12  ? 267.629 203.076 240.251 1.00 123.07 ? 18  C     C "C2'" 1 
ATOM   351  O "O2'" . C     B 1 12  ? 267.380 201.945 241.069 1.00 126.97 ? 18  C     C "O2'" 1 
ATOM   352  C "C1'" . C     B 1 12  ? 268.863 202.778 239.403 1.00 119.77 ? 18  C     C "C1'" 1 
ATOM   353  N N1    . C     B 1 12  ? 269.616 204.003 239.051 1.00 121.61 ? 18  C     C N1    1 
ATOM   354  C C2    . C     B 1 12  ? 270.581 204.458 239.952 1.00 123.31 ? 18  C     C C2    1 
ATOM   355  O O2    . C     B 1 12  ? 270.762 203.823 241.002 1.00 121.72 ? 18  C     C O2    1 
ATOM   356  N N3    . C     B 1 12  ? 271.283 205.577 239.652 1.00 127.28 ? 18  C     C N3    1 
ATOM   357  C C4    . C     B 1 12  ? 271.056 206.233 238.507 1.00 129.17 ? 18  C     C C4    1 
ATOM   358  N N4    . C     B 1 12  ? 271.772 207.321 238.265 1.00 132.74 ? 18  C     C N4    1 
ATOM   359  C C5    . C     B 1 12  ? 270.079 205.781 237.577 1.00 124.85 ? 18  C     C C5    1 
ATOM   360  C C6    . C     B 1 12  ? 269.389 204.672 237.884 1.00 122.54 ? 18  C     C C6    1 
ATOM   361  N N     . SER   C 2 391 ? 246.872 215.190 255.784 1.00 60.08  ? 403 SER   B N     1 
ATOM   362  C CA    . SER   C 2 391 ? 247.420 214.241 254.823 1.00 63.22  ? 403 SER   B CA    1 
ATOM   363  C C     . SER   C 2 391 ? 246.703 212.903 254.900 1.00 61.22  ? 403 SER   B C     1 
ATOM   364  O O     . SER   C 2 391 ? 245.860 212.693 255.770 1.00 62.77  ? 403 SER   B O     1 
ATOM   365  C CB    . SER   C 2 391 ? 248.917 214.041 255.057 1.00 63.99  ? 403 SER   B CB    1 
ATOM   366  O OG    . SER   C 2 391 ? 249.498 213.297 254.000 1.00 59.41  ? 403 SER   B OG    1 
ATOM   367  N N     . GLY   C 2 392 ? 247.035 212.011 253.989 1.00 54.44  ? 404 GLY   B N     1 
ATOM   368  C CA    . GLY   C 2 392 ? 246.447 210.691 253.981 1.00 54.96  ? 404 GLY   B CA    1 
ATOM   369  C C     . GLY   C 2 392 ? 245.999 210.316 252.580 1.00 52.34  ? 404 GLY   B C     1 
ATOM   370  O O     . GLY   C 2 392 ? 246.637 210.680 251.595 1.00 54.86  ? 404 GLY   B O     1 
ATOM   371  N N     . GLN   C 2 393 ? 244.896 209.576 252.525 1.00 50.63  ? 405 GLN   B N     1 
ATOM   372  C CA    . GLN   C 2 393 ? 244.274 209.133 251.281 1.00 49.16  ? 405 GLN   B CA    1 
ATOM   373  C C     . GLN   C 2 393 ? 242.967 209.904 251.135 1.00 51.27  ? 405 GLN   B C     1 
ATOM   374  O O     . GLN   C 2 393 ? 242.051 209.754 251.947 1.00 53.36  ? 405 GLN   B O     1 
ATOM   375  C CB    . GLN   C 2 393 ? 244.043 207.624 251.288 1.00 49.45  ? 405 GLN   B CB    1 
ATOM   376  C CG    . GLN   C 2 393 ? 243.325 207.098 250.063 1.00 48.90  ? 405 GLN   B CG    1 
ATOM   377  C CD    . GLN   C 2 393 ? 243.298 205.587 250.013 1.00 52.75  ? 405 GLN   B CD    1 
ATOM   378  O OE1   . GLN   C 2 393 ? 244.249 204.927 250.423 1.00 60.62  ? 405 GLN   B OE1   1 
ATOM   379  N NE2   . GLN   C 2 393 ? 242.206 205.031 249.510 1.00 50.17  ? 405 GLN   B NE2   1 
ATOM   380  N N     . ILE   C 2 394 ? 242.891 210.754 250.109 1.00 48.30  ? 406 ILE   B N     1 
ATOM   381  C CA    . ILE   C 2 394 ? 241.673 211.516 249.858 1.00 46.87  ? 406 ILE   B CA    1 
ATOM   382  C C     . ILE   C 2 394 ? 240.583 210.706 249.171 1.00 49.26  ? 406 ILE   B C     1 
ATOM   383  O O     . ILE   C 2 394 ? 239.404 210.866 249.506 1.00 51.62  ? 406 ILE   B O     1 
ATOM   384  C CB    . ILE   C 2 394 ? 241.979 212.770 249.013 1.00 48.93  ? 406 ILE   B CB    1 
ATOM   385  C CG1   . ILE   C 2 394 ? 242.564 213.882 249.875 1.00 48.93  ? 406 ILE   B CG1   1 
ATOM   386  C CG2   . ILE   C 2 394 ? 240.736 213.283 248.331 1.00 54.34  ? 406 ILE   B CG2   1 
ATOM   387  C CD1   . ILE   C 2 394 ? 243.151 215.004 249.057 1.00 54.46  ? 406 ILE   B CD1   1 
ATOM   388  N N     . SER   C 2 395 ? 240.935 209.822 248.240 1.00 46.45  ? 407 SER   B N     1 
ATOM   389  C CA    . SER   C 2 395 ? 239.941 209.214 247.369 1.00 45.75  ? 407 SER   B CA    1 
ATOM   390  C C     . SER   C 2 395 ? 240.156 207.711 247.266 1.00 47.42  ? 407 SER   B C     1 
ATOM   391  O O     . SER   C 2 395 ? 241.217 207.189 247.614 1.00 51.50  ? 407 SER   B O     1 
ATOM   392  C CB    . SER   C 2 395 ? 239.974 209.836 245.969 1.00 48.25  ? 407 SER   B CB    1 
ATOM   393  O OG    . SER   C 2 395 ? 239.016 209.228 245.123 1.00 53.63  ? 407 SER   B OG    1 
ATOM   394  N N     . ILE   C 2 396 ? 239.122 207.026 246.799 1.00 47.45  ? 408 ILE   B N     1 
ATOM   395  C CA    . ILE   C 2 396 ? 239.134 205.583 246.589 1.00 45.23  ? 408 ILE   B CA    1 
ATOM   396  C C     . ILE   C 2 396 ? 239.390 205.288 245.120 1.00 47.34  ? 408 ILE   B C     1 
ATOM   397  O O     . ILE   C 2 396 ? 238.882 205.983 244.232 1.00 53.90  ? 408 ILE   B O     1 
ATOM   398  C CB    . ILE   C 2 396 ? 237.806 204.959 247.065 1.00 43.65  ? 408 ILE   B CB    1 
ATOM   399  C CG1   . ILE   C 2 396 ? 237.552 205.290 248.530 1.00 49.02  ? 408 ILE   B CG1   1 
ATOM   400  C CG2   . ILE   C 2 396 ? 237.783 203.452 246.855 1.00 41.60  ? 408 ILE   B CG2   1 
ATOM   401  C CD1   . ILE   C 2 396 ? 238.619 204.816 249.456 1.00 50.94  ? 408 ILE   B CD1   1 
ATOM   402  N N     . GLN   C 2 397 ? 240.202 204.268 244.858 1.00 44.13  ? 409 GLN   B N     1 
ATOM   403  C CA    . GLN   C 2 397 ? 240.337 203.728 243.511 1.00 41.87  ? 409 GLN   B CA    1 
ATOM   404  C C     . GLN   C 2 397 ? 239.694 202.350 243.477 1.00 42.91  ? 409 GLN   B C     1 
ATOM   405  O O     . GLN   C 2 397 ? 240.226 201.410 244.088 1.00 42.10  ? 409 GLN   B O     1 
ATOM   406  C CB    . GLN   C 2 397 ? 241.802 203.649 243.086 1.00 40.76  ? 409 GLN   B CB    1 
ATOM   407  C CG    . GLN   C 2 397 ? 242.000 203.041 241.711 1.00 41.48  ? 409 GLN   B CG    1 
ATOM   408  C CD    . GLN   C 2 397 ? 241.924 204.071 240.602 1.00 42.01  ? 409 GLN   B CD    1 
ATOM   409  O OE1   . GLN   C 2 397 ? 242.681 205.037 240.584 1.00 45.82  ? 409 GLN   B OE1   1 
ATOM   410  N NE2   . GLN   C 2 397 ? 241.001 203.870 239.673 1.00 40.63  ? 409 GLN   B NE2   1 
ATOM   411  N N     . PRO   C 2 398 ? 238.561 202.183 242.800 1.00 43.32  ? 410 PRO   B N     1 
ATOM   412  C CA    . PRO   C 2 398 ? 237.819 200.921 242.891 1.00 44.97  ? 410 PRO   B CA    1 
ATOM   413  C C     . PRO   C 2 398 ? 238.604 199.749 242.323 1.00 47.21  ? 410 PRO   B C     1 
ATOM   414  O O     . PRO   C 2 398 ? 239.207 199.842 241.252 1.00 50.72  ? 410 PRO   B O     1 
ATOM   415  C CB    . PRO   C 2 398 ? 236.558 201.206 242.070 1.00 44.37  ? 410 PRO   B CB    1 
ATOM   416  C CG    . PRO   C 2 398 ? 237.000 202.242 241.096 1.00 43.56  ? 410 PRO   B CG    1 
ATOM   417  C CD    . PRO   C 2 398 ? 237.890 203.136 241.903 1.00 41.75  ? 410 PRO   B CD    1 
ATOM   418  N N     . THR   C 2 399 ? 238.586 198.636 243.053 1.00 45.52  ? 411 THR   B N     1 
ATOM   419  C CA    . THR   C 2 399 ? 239.158 197.375 242.598 1.00 46.48  ? 411 THR   B CA    1 
ATOM   420  C C     . THR   C 2 399 ? 238.086 196.378 242.181 1.00 48.82  ? 411 THR   B C     1 
ATOM   421  O O     . THR   C 2 399 ? 238.209 195.734 241.137 1.00 54.52  ? 411 THR   B O     1 
ATOM   422  C CB    . THR   C 2 399 ? 240.035 196.758 243.694 1.00 46.43  ? 411 THR   B CB    1 
ATOM   423  O OG1   . THR   C 2 399 ? 241.016 197.710 244.119 1.00 57.04  ? 411 THR   B OG1   1 
ATOM   424  C CG2   . THR   C 2 399 ? 240.732 195.515 243.184 1.00 42.78  ? 411 THR   B CG2   1 
ATOM   425  N N     . PHE   C 2 400 ? 237.031 196.248 242.975 1.00 48.25  ? 412 PHE   B N     1 
ATOM   426  C CA    . PHE   C 2 400 ? 235.989 195.262 242.742 1.00 47.48  ? 412 PHE   B CA    1 
ATOM   427  C C     . PHE   C 2 400 ? 234.778 195.916 242.092 1.00 46.65  ? 412 PHE   B C     1 
ATOM   428  O O     . PHE   C 2 400 ? 234.408 197.042 242.434 1.00 48.42  ? 412 PHE   B O     1 
ATOM   429  C CB    . PHE   C 2 400 ? 235.585 194.591 244.054 1.00 44.05  ? 412 PHE   B CB    1 
ATOM   430  C CG    . PHE   C 2 400 ? 236.738 194.000 244.807 1.00 43.88  ? 412 PHE   B CG    1 
ATOM   431  C CD1   . PHE   C 2 400 ? 237.304 192.806 244.403 1.00 45.87  ? 412 PHE   B CD1   1 
ATOM   432  C CD2   . PHE   C 2 400 ? 237.261 194.642 245.914 1.00 44.79  ? 412 PHE   B CD2   1 
ATOM   433  C CE1   . PHE   C 2 400 ? 238.366 192.260 245.089 1.00 42.91  ? 412 PHE   B CE1   1 
ATOM   434  C CE2   . PHE   C 2 400 ? 238.323 194.099 246.606 1.00 45.68  ? 412 PHE   B CE2   1 
ATOM   435  C CZ    . PHE   C 2 400 ? 238.878 192.908 246.191 1.00 41.93  ? 412 PHE   B CZ    1 
ATOM   436  N N     . SER   C 2 401 ? 234.164 195.199 241.152 1.00 46.86  ? 413 SER   B N     1 
ATOM   437  C CA    . SER   C 2 401 ? 232.991 195.691 240.434 1.00 46.27  ? 413 SER   B CA    1 
ATOM   438  C C     . SER   C 2 401 ? 231.759 195.467 241.309 1.00 49.64  ? 413 SER   B C     1 
ATOM   439  O O     . SER   C 2 401 ? 231.013 194.496 241.168 1.00 51.18  ? 413 SER   B O     1 
ATOM   440  C CB    . SER   C 2 401 ? 232.863 195.000 239.083 1.00 45.24  ? 413 SER   B CB    1 
ATOM   441  O OG    . SER   C 2 401 ? 232.157 195.808 238.161 1.00 45.56  ? 413 SER   B OG    1 
ATOM   442  N N     . VAL   C 2 402 ? 231.553 196.396 242.237 1.00 49.43  ? 414 VAL   B N     1 
ATOM   443  C CA    . VAL   C 2 402 ? 230.443 196.365 243.179 1.00 47.96  ? 414 VAL   B CA    1 
ATOM   444  C C     . VAL   C 2 402 ? 229.753 197.720 243.109 1.00 49.77  ? 414 VAL   B C     1 
ATOM   445  O O     . VAL   C 2 402 ? 230.375 198.722 242.745 1.00 52.99  ? 414 VAL   B O     1 
ATOM   446  C CB    . VAL   C 2 402 ? 230.935 196.051 244.612 1.00 47.01  ? 414 VAL   B CB    1 
ATOM   447  C CG1   . VAL   C 2 402 ? 229.781 195.925 245.570 1.00 45.95  ? 414 VAL   B CG1   1 
ATOM   448  C CG2   . VAL   C 2 402 ? 231.769 194.787 244.623 1.00 44.90  ? 414 VAL   B CG2   1 
ATOM   449  N N     . GLN   C 2 403 ? 228.460 197.755 243.455 1.00 47.96  ? 415 GLN   B N     1 
ATOM   450  C CA    . GLN   C 2 403 ? 227.665 198.962 243.244 1.00 49.17  ? 415 GLN   B CA    1 
ATOM   451  C C     . GLN   C 2 403 ? 228.275 200.168 243.946 1.00 52.03  ? 415 GLN   B C     1 
ATOM   452  O O     . GLN   C 2 403 ? 228.824 201.040 243.274 1.00 56.81  ? 415 GLN   B O     1 
ATOM   453  C CB    . GLN   C 2 403 ? 226.223 198.759 243.718 1.00 43.46  ? 415 GLN   B CB    1 
ATOM   454  C CG    . GLN   C 2 403 ? 225.226 199.659 243.000 1.00 41.89  ? 415 GLN   B CG    1 
ATOM   455  C CD    . GLN   C 2 403 ? 223.820 199.546 243.549 1.00 40.94  ? 415 GLN   B CD    1 
ATOM   456  O OE1   . GLN   C 2 403 ? 222.990 198.817 243.014 1.00 42.33  ? 415 GLN   B OE1   1 
ATOM   457  N NE2   . GLN   C 2 403 ? 223.543 200.278 244.619 1.00 40.21  ? 415 GLN   B NE2   1 
ATOM   458  N N     . ARG   C 2 404 ? 228.242 200.185 245.282 1.00 46.29  ? 416 ARG   B N     1 
ATOM   459  C CA    . ARG   C 2 404 ? 228.945 201.119 246.170 1.00 48.40  ? 416 ARG   B CA    1 
ATOM   460  C C     . ARG   C 2 404 ? 228.990 202.602 245.789 1.00 49.28  ? 416 ARG   B C     1 
ATOM   461  O O     . ARG   C 2 404 ? 229.123 202.977 244.623 1.00 49.25  ? 416 ARG   B O     1 
ATOM   462  C CB    . ARG   C 2 404 ? 230.386 200.643 246.374 1.00 49.05  ? 416 ARG   B CB    1 
ATOM   463  C CG    . ARG   C 2 404 ? 231.243 200.708 245.134 1.00 45.07  ? 416 ARG   B CG    1 
ATOM   464  C CD    . ARG   C 2 404 ? 232.700 200.780 245.455 1.00 44.20  ? 416 ARG   B CD    1 
ATOM   465  N NE    . ARG   C 2 404 ? 233.453 199.956 244.524 1.00 46.01  ? 416 ARG   B NE    1 
ATOM   466  C CZ    . ARG   C 2 404 ? 234.720 199.615 244.690 1.00 50.19  ? 416 ARG   B CZ    1 
ATOM   467  N NH1   . ARG   C 2 404 ? 235.420 200.050 245.723 1.00 44.60  ? 416 ARG   B NH1   1 
ATOM   468  N NH2   . ARG   C 2 404 ? 235.296 198.808 243.805 1.00 52.89  ? 416 ARG   B NH2   1 
ATOM   469  N N     . ASN   C 2 405 ? 228.900 203.466 246.790 1.00 51.10  ? 417 ASN   B N     1 
ATOM   470  C CA    . ASN   C 2 405 ? 229.289 204.854 246.602 1.00 48.29  ? 417 ASN   B CA    1 
ATOM   471  C C     . ASN   C 2 405 ? 230.810 204.952 246.546 1.00 52.44  ? 417 ASN   B C     1 
ATOM   472  O O     . ASN   C 2 405 ? 231.516 204.306 247.325 1.00 57.05  ? 417 ASN   B O     1 
ATOM   473  C CB    . ASN   C 2 405 ? 228.735 205.709 247.741 1.00 45.31  ? 417 ASN   B CB    1 
ATOM   474  C CG    . ASN   C 2 405 ? 229.561 206.949 248.000 1.00 55.05  ? 417 ASN   B CG    1 
ATOM   475  O OD1   . ASN   C 2 405 ? 229.912 207.684 247.077 1.00 60.30  ? 417 ASN   B OD1   1 
ATOM   476  N ND2   . ASN   C 2 405 ? 229.878 207.189 249.264 1.00 53.70  ? 417 ASN   B ND2   1 
ATOM   477  N N     . LEU   C 2 406 ? 231.323 205.757 245.616 1.00 45.75  ? 418 LEU   B N     1 
ATOM   478  C CA    . LEU   C 2 406 ? 232.758 205.991 245.565 1.00 46.03  ? 418 LEU   B CA    1 
ATOM   479  C C     . LEU   C 2 406 ? 233.073 207.251 246.349 1.00 47.36  ? 418 LEU   B C     1 
ATOM   480  O O     . LEU   C 2 406 ? 232.728 208.352 245.896 1.00 50.49  ? 418 LEU   B O     1 
ATOM   481  C CB    . LEU   C 2 406 ? 233.252 206.126 244.127 1.00 47.36  ? 418 LEU   B CB    1 
ATOM   482  C CG    . LEU   C 2 406 ? 233.263 204.881 243.245 1.00 45.42  ? 418 LEU   B CG    1 
ATOM   483  C CD1   . LEU   C 2 406 ? 233.497 205.277 241.802 1.00 49.77  ? 418 LEU   B CD1   1 
ATOM   484  C CD2   . LEU   C 2 406 ? 234.324 203.912 243.712 1.00 44.13  ? 418 LEU   B CD2   1 
ATOM   485  N N     . PRO   C 2 407 ? 233.723 207.155 247.502 1.00 46.79  ? 419 PRO   B N     1 
ATOM   486  C CA    . PRO   C 2 407 ? 233.918 208.340 248.337 1.00 47.43  ? 419 PRO   B CA    1 
ATOM   487  C C     . PRO   C 2 407 ? 235.173 209.109 247.966 1.00 47.04  ? 419 PRO   B C     1 
ATOM   488  O O     . PRO   C 2 407 ? 236.171 208.550 247.510 1.00 51.06  ? 419 PRO   B O     1 
ATOM   489  C CB    . PRO   C 2 407 ? 234.028 207.764 249.756 1.00 43.99  ? 419 PRO   B CB    1 
ATOM   490  C CG    . PRO   C 2 407 ? 234.063 206.263 249.606 1.00 45.92  ? 419 PRO   B CG    1 
ATOM   491  C CD    . PRO   C 2 407 ? 234.213 205.937 248.159 1.00 49.00  ? 419 PRO   B CD    1 
ATOM   492  N N     . PHE   C 2 408 ? 235.096 210.422 248.159 1.00 44.64  ? 420 PHE   B N     1 
ATOM   493  C CA    . PHE   C 2 408 ? 236.263 211.285 248.081 1.00 44.54  ? 420 PHE   B CA    1 
ATOM   494  C C     . PHE   C 2 408 ? 236.036 212.478 248.996 1.00 44.32  ? 420 PHE   B C     1 
ATOM   495  O O     . PHE   C 2 408 ? 234.904 212.792 249.369 1.00 44.80  ? 420 PHE   B O     1 
ATOM   496  C CB    . PHE   C 2 408 ? 236.559 211.738 246.644 1.00 46.41  ? 420 PHE   B CB    1 
ATOM   497  C CG    . PHE   C 2 408 ? 235.383 212.338 245.931 1.00 43.98  ? 420 PHE   B CG    1 
ATOM   498  C CD1   . PHE   C 2 408 ? 235.120 213.693 246.016 1.00 43.62  ? 420 PHE   B CD1   1 
ATOM   499  C CD2   . PHE   C 2 408 ? 234.557 211.552 245.151 1.00 45.30  ? 420 PHE   B CD2   1 
ATOM   500  C CE1   . PHE   C 2 408 ? 234.047 214.246 245.353 1.00 44.49  ? 420 PHE   B CE1   1 
ATOM   501  C CE2   . PHE   C 2 408 ? 233.484 212.100 244.487 1.00 45.81  ? 420 PHE   B CE2   1 
ATOM   502  C CZ    . PHE   C 2 408 ? 233.228 213.448 244.589 1.00 44.75  ? 420 PHE   B CZ    1 
ATOM   503  N N     . ASP   C 2 409 ? 237.132 213.128 249.373 1.00 44.59  ? 421 ASP   B N     1 
ATOM   504  C CA    . ASP   C 2 409 ? 237.071 214.309 250.232 1.00 46.47  ? 421 ASP   B CA    1 
ATOM   505  C C     . ASP   C 2 409 ? 236.872 215.519 249.333 1.00 48.05  ? 421 ASP   B C     1 
ATOM   506  O O     . ASP   C 2 409 ? 237.827 216.158 248.890 1.00 50.94  ? 421 ASP   B O     1 
ATOM   507  C CB    . ASP   C 2 409 ? 238.330 214.430 251.079 1.00 49.47  ? 421 ASP   B CB    1 
ATOM   508  C CG    . ASP   C 2 409 ? 238.055 215.010 252.447 1.00 54.36  ? 421 ASP   B CG    1 
ATOM   509  O OD1   . ASP   C 2 409 ? 237.012 215.674 252.612 1.00 54.71  ? 421 ASP   B OD1   1 
ATOM   510  O OD2   . ASP   C 2 409 ? 238.880 214.804 253.358 1.00 60.54  ? 421 ASP   B OD2   1 
ATOM   511  N N     . ARG   C 2 410 ? 235.609 215.832 249.059 1.00 46.64  ? 422 ARG   B N     1 
ATOM   512  C CA    . ARG   C 2 410 ? 235.294 216.901 248.114 1.00 47.08  ? 422 ARG   B CA    1 
ATOM   513  C C     . ARG   C 2 410 ? 235.818 218.265 248.541 1.00 48.74  ? 422 ARG   B C     1 
ATOM   514  O O     . ARG   C 2 410 ? 236.400 218.964 247.693 1.00 48.58  ? 422 ARG   B O     1 
ATOM   515  C CB    . ARG   C 2 410 ? 233.784 216.943 247.869 1.00 46.31  ? 422 ARG   B CB    1 
ATOM   516  C CG    . ARG   C 2 410 ? 233.390 217.869 246.746 1.00 44.43  ? 422 ARG   B CG    1 
ATOM   517  C CD    . ARG   C 2 410 ? 231.897 218.055 246.684 1.00 44.21  ? 422 ARG   B CD    1 
ATOM   518  N NE    . ARG   C 2 410 ? 231.533 218.998 245.637 1.00 45.26  ? 422 ARG   B NE    1 
ATOM   519  C CZ    . ARG   C 2 410 ? 231.054 220.211 245.863 1.00 52.26  ? 422 ARG   B CZ    1 
ATOM   520  N NH1   . ARG   C 2 410 ? 230.857 220.657 247.092 1.00 56.29  ? 422 ARG   B NH1   1 
ATOM   521  N NH2   . ARG   C 2 410 ? 230.763 220.996 244.831 1.00 56.77  ? 422 ARG   B NH2   1 
ATOM   522  N N     . PRO   C 2 411 ? 235.630 218.728 249.785 1.00 51.80  ? 423 PRO   B N     1 
ATOM   523  C CA    . PRO   C 2 411 ? 236.163 220.057 250.131 1.00 48.17  ? 423 PRO   B CA    1 
ATOM   524  C C     . PRO   C 2 411 ? 237.666 220.170 249.953 1.00 45.98  ? 423 PRO   B C     1 
ATOM   525  O O     . PRO   C 2 411 ? 238.146 221.201 249.471 1.00 45.35  ? 423 PRO   B O     1 
ATOM   526  C CB    . PRO   C 2 411 ? 235.740 220.239 251.597 1.00 45.88  ? 423 PRO   B CB    1 
ATOM   527  C CG    . PRO   C 2 411 ? 235.378 218.889 252.082 1.00 49.12  ? 423 PRO   B CG    1 
ATOM   528  C CD    . PRO   C 2 411 ? 234.855 218.154 250.898 1.00 52.70  ? 423 PRO   B CD    1 
ATOM   529  N N     . THR   C 2 412 ? 238.422 219.124 250.293 1.00 47.03  ? 424 THR   B N     1 
ATOM   530  C CA    . THR   C 2 412 ? 239.875 219.193 250.164 1.00 48.10  ? 424 THR   B CA    1 
ATOM   531  C C     . THR   C 2 412 ? 240.305 219.258 248.704 1.00 50.38  ? 424 THR   B C     1 
ATOM   532  O O     . THR   C 2 412 ? 241.216 220.017 248.354 1.00 51.19  ? 424 THR   B O     1 
ATOM   533  C CB    . THR   C 2 412 ? 240.525 218.001 250.863 1.00 49.94  ? 424 THR   B CB    1 
ATOM   534  O OG1   . THR   C 2 412 ? 239.897 217.791 252.132 1.00 53.76  ? 424 THR   B OG1   1 
ATOM   535  C CG2   . THR   C 2 412 ? 242.003 218.256 251.078 1.00 46.56  ? 424 THR   B CG2   1 
ATOM   536  N N     . ILE   C 2 413 ? 239.672 218.467 247.837 1.00 50.08  ? 425 ILE   B N     1 
ATOM   537  C CA    . ILE   C 2 413 ? 240.010 218.511 246.418 1.00 47.90  ? 425 ILE   B CA    1 
ATOM   538  C C     . ILE   C 2 413 ? 239.608 219.848 245.811 1.00 50.35  ? 425 ILE   B C     1 
ATOM   539  O O     . ILE   C 2 413 ? 240.345 220.426 245.005 1.00 51.16  ? 425 ILE   B O     1 
ATOM   540  C CB    . ILE   C 2 413 ? 239.352 217.336 245.674 1.00 50.58  ? 425 ILE   B CB    1 
ATOM   541  C CG1   . ILE   C 2 413 ? 239.786 216.009 246.283 1.00 44.39  ? 425 ILE   B CG1   1 
ATOM   542  C CG2   . ILE   C 2 413 ? 239.714 217.372 244.202 1.00 54.68  ? 425 ILE   B CG2   1 
ATOM   543  C CD1   . ILE   C 2 413 ? 239.254 214.818 245.542 1.00 43.36  ? 425 ILE   B CD1   1 
ATOM   544  N N     . MET   C 2 414 ? 238.434 220.358 246.184 1.00 51.61  ? 426 MET   B N     1 
ATOM   545  C CA    . MET   C 2 414 ? 237.920 221.577 245.571 1.00 51.55  ? 426 MET   B CA    1 
ATOM   546  C C     . MET   C 2 414 ? 238.658 222.821 246.045 1.00 51.78  ? 426 MET   B C     1 
ATOM   547  O O     . MET   C 2 414 ? 238.804 223.775 245.274 1.00 56.61  ? 426 MET   B O     1 
ATOM   548  C CB    . MET   C 2 414 ? 236.425 221.711 245.850 1.00 55.28  ? 426 MET   B CB    1 
ATOM   549  C CG    . MET   C 2 414 ? 235.532 220.908 244.918 1.00 57.30  ? 426 MET   B CG    1 
ATOM   550  S SD    . MET   C 2 414 ? 235.897 221.174 243.172 1.00 54.25  ? 426 MET   B SD    1 
ATOM   551  C CE    . MET   C 2 414 ? 236.830 219.703 242.788 1.00 44.32  ? 426 MET   B CE    1 
ATOM   552  N N     . ALA   C 2 415 ? 239.129 222.837 247.296 1.00 50.84  ? 427 ALA   B N     1 
ATOM   553  C CA    . ALA   C 2 415 ? 239.799 224.022 247.817 1.00 52.77  ? 427 ALA   B CA    1 
ATOM   554  C C     . ALA   C 2 415 ? 241.069 224.355 247.049 1.00 54.36  ? 427 ALA   B C     1 
ATOM   555  O O     . ALA   C 2 415 ? 241.522 225.503 247.093 1.00 60.64  ? 427 ALA   B O     1 
ATOM   556  C CB    . ALA   C 2 415 ? 240.119 223.836 249.300 1.00 53.91  ? 427 ALA   B CB    1 
ATOM   557  N N     . ALA   C 2 416 ? 241.648 223.388 246.345 1.00 48.44  ? 428 ALA   B N     1 
ATOM   558  C CA    . ALA   C 2 416 ? 242.784 223.641 245.472 1.00 49.40  ? 428 ALA   B CA    1 
ATOM   559  C C     . ALA   C 2 416 ? 242.363 224.125 244.092 1.00 51.27  ? 428 ALA   B C     1 
ATOM   560  O O     . ALA   C 2 416 ? 243.228 224.389 243.252 1.00 49.22  ? 428 ALA   B O     1 
ATOM   561  C CB    . ALA   C 2 416 ? 243.640 222.380 245.339 1.00 49.08  ? 428 ALA   B CB    1 
ATOM   562  N N     . PHE   C 2 417 ? 241.056 224.249 243.843 1.00 55.58  ? 429 PHE   B N     1 
ATOM   563  C CA    . PHE   C 2 417 ? 240.538 224.679 242.550 1.00 54.12  ? 429 PHE   B CA    1 
ATOM   564  C C     . PHE   C 2 417 ? 239.637 225.902 242.672 1.00 53.54  ? 429 PHE   B C     1 
ATOM   565  O O     . PHE   C 2 417 ? 238.763 226.104 241.824 1.00 53.02  ? 429 PHE   B O     1 
ATOM   566  C CB    . PHE   C 2 417 ? 239.776 223.542 241.869 1.00 51.11  ? 429 PHE   B CB    1 
ATOM   567  C CG    . PHE   C 2 417 ? 240.663 222.501 241.270 1.00 51.01  ? 429 PHE   B CG    1 
ATOM   568  C CD1   . PHE   C 2 417 ? 241.883 222.848 240.731 1.00 57.36  ? 429 PHE   B CD1   1 
ATOM   569  C CD2   . PHE   C 2 417 ? 240.277 221.175 241.241 1.00 52.67  ? 429 PHE   B CD2   1 
ATOM   570  C CE1   . PHE   C 2 417 ? 242.704 221.894 240.183 1.00 59.72  ? 429 PHE   B CE1   1 
ATOM   571  C CE2   . PHE   C 2 417 ? 241.096 220.219 240.688 1.00 50.39  ? 429 PHE   B CE2   1 
ATOM   572  C CZ    . PHE   C 2 417 ? 242.306 220.580 240.154 1.00 55.60  ? 429 PHE   B CZ    1 
ATOM   573  N N     . THR   C 2 418 ? 239.820 226.712 243.706 1.00 51.31  ? 430 THR   B N     1 
ATOM   574  C CA    . THR   C 2 418 ? 239.005 227.906 243.882 1.00 58.02  ? 430 THR   B CA    1 
ATOM   575  C C     . THR   C 2 418 ? 239.882 229.141 244.053 1.00 57.98  ? 430 THR   B C     1 
ATOM   576  O O     . THR   C 2 418 ? 240.000 229.960 243.142 1.00 50.09  ? 430 THR   B O     1 
ATOM   577  C CB    . THR   C 2 418 ? 238.067 227.774 245.093 1.00 60.62  ? 430 THR   B CB    1 
ATOM   578  O OG1   . THR   C 2 418 ? 236.962 226.929 244.752 1.00 55.95  ? 430 THR   B OG1   1 
ATOM   579  C CG2   . THR   C 2 418 ? 237.542 229.137 245.510 1.00 59.96  ? 430 THR   B CG2   1 
ATOM   580  N N     . GLU   D 2 6   ? 233.472 183.690 219.735 1.00 104.60 ? 18  GLU   A N     1 
ATOM   581  C CA    . GLU   D 2 6   ? 233.584 184.578 220.885 1.00 102.74 ? 18  GLU   A CA    1 
ATOM   582  C C     . GLU   D 2 6   ? 233.924 183.801 222.155 1.00 94.89  ? 18  GLU   A C     1 
ATOM   583  O O     . GLU   D 2 6   ? 234.677 184.279 223.002 1.00 95.20  ? 18  GLU   A O     1 
ATOM   584  C CB    . GLU   D 2 6   ? 232.287 185.382 221.076 1.00 109.88 ? 18  GLU   A CB    1 
ATOM   585  C CG    . GLU   D 2 6   ? 231.909 186.430 219.998 1.00 118.03 ? 18  GLU   A CG    1 
ATOM   586  C CD    . GLU   D 2 6   ? 230.571 187.154 220.198 1.00 122.37 ? 18  GLU   A CD    1 
ATOM   587  O OE1   . GLU   D 2 6   ? 229.810 186.719 221.088 1.00 120.70 ? 18  GLU   A OE1   1 
ATOM   588  O OE2   . GLU   D 2 6   ? 230.266 188.142 219.498 1.00 119.33 ? 18  GLU   A OE2   1 
ATOM   589  N N     . ARG   D 2 7   ? 233.359 182.601 222.287 1.00 87.95  ? 19  ARG   A N     1 
ATOM   590  C CA    . ARG   D 2 7   ? 233.690 181.742 223.417 1.00 88.11  ? 19  ARG   A CA    1 
ATOM   591  C C     . ARG   D 2 7   ? 235.045 181.072 223.236 1.00 82.86  ? 19  ARG   A C     1 
ATOM   592  O O     . ARG   D 2 7   ? 235.770 180.858 224.219 1.00 83.18  ? 19  ARG   A O     1 
ATOM   593  C CB    . ARG   D 2 7   ? 232.601 180.686 223.602 1.00 101.59 ? 19  ARG   A CB    1 
ATOM   594  C CG    . ARG   D 2 7   ? 232.384 180.237 225.037 1.00 108.08 ? 19  ARG   A CG    1 
ATOM   595  C CD    . ARG   D 2 7   ? 231.255 181.014 225.702 1.00 108.96 ? 19  ARG   A CD    1 
ATOM   596  N NE    . ARG   D 2 7   ? 230.090 181.142 224.835 1.00 105.58 ? 19  ARG   A NE    1 
ATOM   597  C CZ    . ARG   D 2 7   ? 229.257 180.154 224.538 1.00 101.44 ? 19  ARG   A CZ    1 
ATOM   598  N NH1   . ARG   D 2 7   ? 229.421 178.937 225.031 1.00 95.86  ? 19  ARG   A NH1   1 
ATOM   599  N NH2   . ARG   D 2 7   ? 228.233 180.392 223.724 1.00 108.77 ? 19  ARG   A NH2   1 
ATOM   600  N N     . GLN   D 2 8   ? 235.400 180.745 221.992 1.00 79.50  ? 20  GLN   A N     1 
ATOM   601  C CA    . GLN   D 2 8   ? 236.664 180.067 221.728 1.00 76.02  ? 20  GLN   A CA    1 
ATOM   602  C C     . GLN   D 2 8   ? 237.847 180.937 222.129 1.00 74.70  ? 20  GLN   A C     1 
ATOM   603  O O     . GLN   D 2 8   ? 238.801 180.456 222.751 1.00 75.98  ? 20  GLN   A O     1 
ATOM   604  C CB    . GLN   D 2 8   ? 236.746 179.685 220.251 1.00 75.71  ? 20  GLN   A CB    1 
ATOM   605  C CG    . GLN   D 2 8   ? 238.053 179.038 219.853 1.00 84.36  ? 20  GLN   A CG    1 
ATOM   606  C CD    . GLN   D 2 8   ? 238.021 177.535 220.003 1.00 95.76  ? 20  GLN   A CD    1 
ATOM   607  O OE1   . GLN   D 2 8   ? 236.952 176.926 220.033 1.00 98.19  ? 20  GLN   A OE1   1 
ATOM   608  N NE2   . GLN   D 2 8   ? 239.195 176.925 220.100 1.00 99.51  ? 20  GLN   A NE2   1 
ATOM   609  N N     . ASN   D 2 9   ? 237.799 182.226 221.791 1.00 69.94  ? 21  ASN   A N     1 
ATOM   610  C CA    . ASN   D 2 9   ? 238.878 183.125 222.183 1.00 68.17  ? 21  ASN   A CA    1 
ATOM   611  C C     . ASN   D 2 9   ? 239.013 183.185 223.696 1.00 66.82  ? 21  ASN   A C     1 
ATOM   612  O O     . ASN   D 2 9   ? 240.129 183.193 224.228 1.00 69.40  ? 21  ASN   A O     1 
ATOM   613  C CB    . ASN   D 2 9   ? 238.640 184.521 221.612 1.00 72.29  ? 21  ASN   A CB    1 
ATOM   614  C CG    . ASN   D 2 9   ? 239.920 185.185 221.148 1.00 75.35  ? 21  ASN   A CG    1 
ATOM   615  O OD1   . ASN   D 2 9   ? 240.953 184.533 221.000 1.00 73.30  ? 21  ASN   A OD1   1 
ATOM   616  N ND2   . ASN   D 2 9   ? 239.862 186.492 220.924 1.00 71.60  ? 21  ASN   A ND2   1 
ATOM   617  N N     . ALA   D 2 10  ? 237.885 183.222 224.406 1.00 63.40  ? 22  ALA   A N     1 
ATOM   618  C CA    . ALA   D 2 10  ? 237.929 183.248 225.862 1.00 63.58  ? 22  ALA   A CA    1 
ATOM   619  C C     . ALA   D 2 10  ? 238.577 181.988 226.419 1.00 61.85  ? 22  ALA   A C     1 
ATOM   620  O O     . ALA   D 2 10  ? 239.381 182.058 227.358 1.00 61.84  ? 22  ALA   A O     1 
ATOM   621  C CB    . ALA   D 2 10  ? 236.521 183.424 226.426 1.00 68.44  ? 22  ALA   A CB    1 
ATOM   622  N N     . THR   D 2 11  ? 238.247 180.823 225.854 1.00 61.59  ? 23  THR   A N     1 
ATOM   623  C CA    . THR   D 2 11  ? 238.850 179.599 226.373 1.00 60.27  ? 23  THR   A CA    1 
ATOM   624  C C     . THR   D 2 11  ? 240.346 179.526 226.060 1.00 60.08  ? 23  THR   A C     1 
ATOM   625  O O     . THR   D 2 11  ? 241.120 179.033 226.889 1.00 57.32  ? 23  THR   A O     1 
ATOM   626  C CB    . THR   D 2 11  ? 238.101 178.363 225.859 1.00 61.48  ? 23  THR   A CB    1 
ATOM   627  O OG1   . THR   D 2 11  ? 238.292 177.280 226.776 1.00 67.60  ? 23  THR   A OG1   1 
ATOM   628  C CG2   . THR   D 2 11  ? 238.585 177.927 224.490 1.00 71.41  ? 23  THR   A CG2   1 
ATOM   629  N N     . GLU   D 2 12  ? 240.785 180.048 224.907 1.00 62.49  ? 24  GLU   A N     1 
ATOM   630  C CA    . GLU   D 2 12  ? 242.226 180.107 224.648 1.00 61.97  ? 24  GLU   A CA    1 
ATOM   631  C C     . GLU   D 2 12  ? 242.928 181.077 225.590 1.00 59.26  ? 24  GLU   A C     1 
ATOM   632  O O     . GLU   D 2 12  ? 244.057 180.818 226.023 1.00 58.62  ? 24  GLU   A O     1 
ATOM   633  C CB    . GLU   D 2 12  ? 242.525 180.485 223.196 1.00 64.16  ? 24  GLU   A CB    1 
ATOM   634  C CG    . GLU   D 2 12  ? 241.606 179.899 222.161 1.00 71.14  ? 24  GLU   A CG    1 
ATOM   635  C CD    . GLU   D 2 12  ? 242.148 178.617 221.570 1.00 88.87  ? 24  GLU   A CD    1 
ATOM   636  O OE1   . GLU   D 2 12  ? 243.138 178.085 222.114 1.00 92.37  ? 24  GLU   A OE1   1 
ATOM   637  O OE2   . GLU   D 2 12  ? 241.590 178.144 220.559 1.00 99.06  ? 24  GLU   A OE2   1 
ATOM   638  N N     . ILE   D 2 13  ? 242.293 182.208 225.901 1.00 57.28  ? 25  ILE   A N     1 
ATOM   639  C CA    . ILE   D 2 13  ? 242.891 183.154 226.841 1.00 56.45  ? 25  ILE   A CA    1 
ATOM   640  C C     . ILE   D 2 13  ? 243.051 182.505 228.208 1.00 54.53  ? 25  ILE   A C     1 
ATOM   641  O O     . ILE   D 2 13  ? 244.100 182.628 228.861 1.00 57.90  ? 25  ILE   A O     1 
ATOM   642  C CB    . ILE   D 2 13  ? 242.045 184.438 226.923 1.00 57.11  ? 25  ILE   A CB    1 
ATOM   643  C CG1   . ILE   D 2 13  ? 242.120 185.224 225.613 1.00 53.88  ? 25  ILE   A CG1   1 
ATOM   644  C CG2   . ILE   D 2 13  ? 242.494 185.295 228.090 1.00 60.88  ? 25  ILE   A CG2   1 
ATOM   645  C CD1   . ILE   D 2 13  ? 243.478 185.203 224.958 1.00 63.46  ? 25  ILE   A CD1   1 
ATOM   646  N N     . ARG   D 2 14  ? 242.011 181.801 228.659 1.00 52.76  ? 26  ARG   A N     1 
ATOM   647  C CA    . ARG   D 2 14  ? 242.091 181.097 229.932 1.00 53.10  ? 26  ARG   A CA    1 
ATOM   648  C C     . ARG   D 2 14  ? 243.196 180.050 229.908 1.00 53.29  ? 26  ARG   A C     1 
ATOM   649  O O     . ARG   D 2 14  ? 243.944 179.908 230.881 1.00 54.03  ? 26  ARG   A O     1 
ATOM   650  C CB    . ARG   D 2 14  ? 240.744 180.457 230.259 1.00 52.55  ? 26  ARG   A CB    1 
ATOM   651  C CG    . ARG   D 2 14  ? 239.675 181.454 230.654 1.00 54.29  ? 26  ARG   A CG    1 
ATOM   652  C CD    . ARG   D 2 14  ? 238.382 180.759 231.009 1.00 53.12  ? 26  ARG   A CD    1 
ATOM   653  N NE    . ARG   D 2 14  ? 238.051 180.920 232.418 1.00 52.33  ? 26  ARG   A NE    1 
ATOM   654  C CZ    . ARG   D 2 14  ? 238.266 179.996 233.343 1.00 50.87  ? 26  ARG   A CZ    1 
ATOM   655  N NH1   . ARG   D 2 14  ? 238.812 178.831 233.042 1.00 51.27  ? 26  ARG   A NH1   1 
ATOM   656  N NH2   . ARG   D 2 14  ? 237.926 180.249 234.603 1.00 52.92  ? 26  ARG   A NH2   1 
ATOM   657  N N     . ALA   D 2 15  ? 243.322 179.318 228.799 1.00 56.91  ? 27  ALA   A N     1 
ATOM   658  C CA    . ALA   D 2 15  ? 244.370 178.307 228.693 1.00 57.27  ? 27  ALA   A CA    1 
ATOM   659  C C     . ALA   D 2 15  ? 245.761 178.930 228.758 1.00 55.76  ? 27  ALA   A C     1 
ATOM   660  O O     . ALA   D 2 15  ? 246.662 178.378 229.395 1.00 56.27  ? 27  ALA   A O     1 
ATOM   661  C CB    . ALA   D 2 15  ? 244.198 177.510 227.403 1.00 58.19  ? 27  ALA   A CB    1 
ATOM   662  N N     . SER   D 2 16  ? 245.959 180.072 228.097 1.00 52.06  ? 28  SER   A N     1 
ATOM   663  C CA    . SER   D 2 16  ? 247.268 180.723 228.120 1.00 51.69  ? 28  SER   A CA    1 
ATOM   664  C C     . SER   D 2 16  ? 247.626 181.206 229.525 1.00 53.00  ? 28  SER   A C     1 
ATOM   665  O O     . SER   D 2 16  ? 248.757 181.010 230.002 1.00 54.04  ? 28  SER   A O     1 
ATOM   666  C CB    . SER   D 2 16  ? 247.286 181.885 227.127 1.00 52.57  ? 28  SER   A CB    1 
ATOM   667  O OG    . SER   D 2 16  ? 246.515 182.972 227.603 1.00 58.94  ? 28  SER   A OG    1 
ATOM   668  N N     . VAL   D 2 17  ? 246.668 181.839 230.208 1.00 52.72  ? 29  VAL   A N     1 
ATOM   669  C CA    . VAL   D 2 17  ? 246.922 182.291 231.575 1.00 53.23  ? 29  VAL   A CA    1 
ATOM   670  C C     . VAL   D 2 17  ? 247.204 181.101 232.486 1.00 52.25  ? 29  VAL   A C     1 
ATOM   671  O O     . VAL   D 2 17  ? 248.094 181.150 233.349 1.00 54.96  ? 29  VAL   A O     1 
ATOM   672  C CB    . VAL   D 2 17  ? 245.744 183.138 232.088 1.00 51.67  ? 29  VAL   A CB    1 
ATOM   673  C CG1   . VAL   D 2 17  ? 246.000 183.593 233.510 1.00 53.22  ? 29  VAL   A CG1   1 
ATOM   674  C CG2   . VAL   D 2 17  ? 245.528 184.335 231.185 1.00 50.52  ? 29  VAL   A CG2   1 
ATOM   675  N N     . GLY   D 2 18  ? 246.456 180.011 232.308 1.00 49.18  ? 30  GLY   A N     1 
ATOM   676  C CA    . GLY   D 2 18  ? 246.716 178.815 233.088 1.00 50.17  ? 30  GLY   A CA    1 
ATOM   677  C C     . GLY   D 2 18  ? 248.084 178.225 232.809 1.00 51.76  ? 30  GLY   A C     1 
ATOM   678  O O     . GLY   D 2 18  ? 248.730 177.687 233.706 1.00 52.72  ? 30  GLY   A O     1 
ATOM   679  N N     . LYS   D 2 19  ? 248.537 178.310 231.558 1.00 53.11  ? 31  LYS   A N     1 
ATOM   680  C CA    . LYS   D 2 19  ? 249.881 177.855 231.221 1.00 51.37  ? 31  LYS   A CA    1 
ATOM   681  C C     . LYS   D 2 19  ? 250.930 178.653 231.979 1.00 50.60  ? 31  LYS   A C     1 
ATOM   682  O O     . LYS   D 2 19  ? 251.890 178.085 232.519 1.00 52.85  ? 31  LYS   A O     1 
ATOM   683  C CB    . LYS   D 2 19  ? 250.105 177.971 229.716 1.00 53.07  ? 31  LYS   A CB    1 
ATOM   684  C CG    . LYS   D 2 19  ? 251.079 176.964 229.148 1.00 54.95  ? 31  LYS   A CG    1 
ATOM   685  C CD    . LYS   D 2 19  ? 250.985 176.915 227.638 1.00 56.19  ? 31  LYS   A CD    1 
ATOM   686  C CE    . LYS   D 2 19  ? 252.148 177.634 226.993 1.00 61.24  ? 31  LYS   A CE    1 
ATOM   687  N NZ    . LYS   D 2 19  ? 253.396 176.831 227.072 1.00 65.36  ? 31  LYS   A NZ    1 
ATOM   688  N N     . MET   D 2 20  ? 250.754 179.975 232.039 1.00 50.77  ? 32  MET   A N     1 
ATOM   689  C CA    . MET   D 2 20  ? 251.679 180.799 232.816 1.00 50.51  ? 32  MET   A CA    1 
ATOM   690  C C     . MET   D 2 20  ? 251.670 180.400 234.291 1.00 51.86  ? 32  MET   A C     1 
ATOM   691  O O     . MET   D 2 20  ? 252.733 180.252 234.914 1.00 52.99  ? 32  MET   A O     1 
ATOM   692  C CB    . MET   D 2 20  ? 251.327 182.279 232.649 1.00 48.19  ? 32  MET   A CB    1 
ATOM   693  C CG    . MET   D 2 20  ? 251.553 183.129 233.888 1.00 50.05  ? 32  MET   A CG    1 
ATOM   694  S SD    . MET   D 2 20  ? 251.181 184.871 233.619 1.00 57.77  ? 32  MET   A SD    1 
ATOM   695  C CE    . MET   D 2 20  ? 249.535 184.978 234.304 1.00 51.76  ? 32  MET   A CE    1 
ATOM   696  N N     . ILE   D 2 21  ? 250.477 180.202 234.858 1.00 51.23  ? 33  ILE   A N     1 
ATOM   697  C CA    . ILE   D 2 21  ? 250.375 179.848 236.274 1.00 49.58  ? 33  ILE   A CA    1 
ATOM   698  C C     . ILE   D 2 21  ? 251.027 178.495 236.540 1.00 50.18  ? 33  ILE   A C     1 
ATOM   699  O O     . ILE   D 2 21  ? 251.733 178.314 237.541 1.00 51.55  ? 33  ILE   A O     1 
ATOM   700  C CB    . ILE   D 2 21  ? 248.903 179.864 236.725 1.00 49.79  ? 33  ILE   A CB    1 
ATOM   701  C CG1   . ILE   D 2 21  ? 248.318 181.271 236.602 1.00 48.72  ? 33  ILE   A CG1   1 
ATOM   702  C CG2   . ILE   D 2 21  ? 248.777 179.365 238.149 1.00 50.11  ? 33  ILE   A CG2   1 
ATOM   703  C CD1   . ILE   D 2 21  ? 249.195 182.347 237.177 1.00 52.60  ? 33  ILE   A CD1   1 
ATOM   704  N N     . ASP   D 2 22  ? 250.792 177.525 235.655 1.00 50.22  ? 34  ASP   A N     1 
ATOM   705  C CA    . ASP   D 2 22  ? 251.376 176.198 235.811 1.00 51.71  ? 34  ASP   A CA    1 
ATOM   706  C C     . ASP   D 2 22  ? 252.894 176.256 235.740 1.00 51.48  ? 34  ASP   A C     1 
ATOM   707  O O     . ASP   D 2 22  ? 253.585 175.569 236.502 1.00 53.17  ? 34  ASP   A O     1 
ATOM   708  C CB    . ASP   D 2 22  ? 250.823 175.263 234.736 1.00 54.02  ? 34  ASP   A CB    1 
ATOM   709  C CG    . ASP   D 2 22  ? 250.864 173.809 235.148 1.00 62.84  ? 34  ASP   A CG    1 
ATOM   710  O OD1   . ASP   D 2 22  ? 250.969 173.535 236.359 1.00 71.12  ? 34  ASP   A OD1   1 
ATOM   711  O OD2   . ASP   D 2 22  ? 250.791 172.936 234.259 1.00 60.97  ? 34  ASP   A OD2   1 
ATOM   712  N N     . GLY   D 2 23  ? 253.430 177.063 234.823 1.00 50.76  ? 35  GLY   A N     1 
ATOM   713  C CA    . GLY   D 2 23  ? 254.871 177.231 234.761 1.00 49.61  ? 35  GLY   A CA    1 
ATOM   714  C C     . GLY   D 2 23  ? 255.443 177.806 236.041 1.00 52.13  ? 35  GLY   A C     1 
ATOM   715  O O     . GLY   D 2 23  ? 256.451 177.313 236.558 1.00 54.29  ? 35  GLY   A O     1 
ATOM   716  N N     . ILE   D 2 24  ? 254.795 178.841 236.583 1.00 51.93  ? 36  ILE   A N     1 
ATOM   717  C CA    . ILE   D 2 24  ? 255.265 179.429 237.839 1.00 51.58  ? 36  ILE   A CA    1 
ATOM   718  C C     . ILE   D 2 24  ? 255.238 178.390 238.956 1.00 52.69  ? 36  ILE   A C     1 
ATOM   719  O O     . ILE   D 2 24  ? 256.196 178.252 239.730 1.00 54.30  ? 36  ILE   A O     1 
ATOM   720  C CB    . ILE   D 2 24  ? 254.423 180.663 238.207 1.00 48.96  ? 36  ILE   A CB    1 
ATOM   721  C CG1   . ILE   D 2 24  ? 254.513 181.729 237.119 1.00 49.31  ? 36  ILE   A CG1   1 
ATOM   722  C CG2   . ILE   D 2 24  ? 254.879 181.235 239.535 1.00 50.00  ? 36  ILE   A CG2   1 
ATOM   723  C CD1   . ILE   D 2 24  ? 253.728 182.973 237.441 1.00 50.41  ? 36  ILE   A CD1   1 
ATOM   724  N N     . GLY   D 2 25  ? 254.140 177.639 239.051 1.00 48.72  ? 37  GLY   A N     1 
ATOM   725  C CA    . GLY   D 2 25  ? 254.013 176.667 240.125 1.00 51.06  ? 37  GLY   A CA    1 
ATOM   726  C C     . GLY   D 2 25  ? 255.035 175.550 240.040 1.00 50.02  ? 37  GLY   A C     1 
ATOM   727  O O     . GLY   D 2 25  ? 255.629 175.157 241.049 1.00 51.71  ? 37  GLY   A O     1 
ATOM   728  N N     . ARG   D 2 26  ? 255.259 175.021 238.837 1.00 50.22  ? 38  ARG   A N     1 
ATOM   729  C CA    . ARG   D 2 26  ? 256.216 173.929 238.713 1.00 51.71  ? 38  ARG   A CA    1 
ATOM   730  C C     . ARG   D 2 26  ? 257.647 174.425 238.880 1.00 48.96  ? 38  ARG   A C     1 
ATOM   731  O O     . ARG   D 2 26  ? 258.504 173.682 239.377 1.00 44.68  ? 38  ARG   A O     1 
ATOM   732  C CB    . ARG   D 2 26  ? 256.012 173.201 237.384 1.00 50.10  ? 38  ARG   A CB    1 
ATOM   733  C CG    . ARG   D 2 26  ? 256.868 173.666 236.241 1.00 56.37  ? 38  ARG   A CG    1 
ATOM   734  C CD    . ARG   D 2 26  ? 256.813 172.648 235.121 1.00 59.65  ? 38  ARG   A CD    1 
ATOM   735  N NE    . ARG   D 2 26  ? 255.444 172.371 234.706 1.00 57.00  ? 38  ARG   A NE    1 
ATOM   736  C CZ    . ARG   D 2 26  ? 254.868 172.892 233.632 1.00 58.47  ? 38  ARG   A CZ    1 
ATOM   737  N NH1   . ARG   D 2 26  ? 255.510 173.735 232.843 1.00 56.34  ? 38  ARG   A NH1   1 
ATOM   738  N NH2   . ARG   D 2 26  ? 253.614 172.558 233.343 1.00 59.93  ? 38  ARG   A NH2   1 
ATOM   739  N N     . PHE   D 2 27  ? 257.919 175.686 238.527 1.00 51.02  ? 39  PHE   A N     1 
ATOM   740  C CA    . PHE   D 2 27  ? 259.209 176.262 238.883 1.00 52.31  ? 39  PHE   A CA    1 
ATOM   741  C C     . PHE   D 2 27  ? 259.380 176.323 240.393 1.00 51.67  ? 39  PHE   A C     1 
ATOM   742  O O     . PHE   D 2 27  ? 260.464 176.035 240.913 1.00 50.34  ? 39  PHE   A O     1 
ATOM   743  C CB    . PHE   D 2 27  ? 259.367 177.659 238.290 1.00 50.92  ? 39  PHE   A CB    1 
ATOM   744  C CG    . PHE   D 2 27  ? 260.580 178.378 238.794 1.00 55.85  ? 39  PHE   A CG    1 
ATOM   745  C CD1   . PHE   D 2 27  ? 261.809 178.192 238.191 1.00 56.31  ? 39  PHE   A CD1   1 
ATOM   746  C CD2   . PHE   D 2 27  ? 260.501 179.213 239.891 1.00 54.58  ? 39  PHE   A CD2   1 
ATOM   747  C CE1   . PHE   D 2 27  ? 262.931 178.839 238.662 1.00 54.83  ? 39  PHE   A CE1   1 
ATOM   748  C CE2   . PHE   D 2 27  ? 261.616 179.846 240.367 1.00 49.76  ? 39  PHE   A CE2   1 
ATOM   749  C CZ    . PHE   D 2 27  ? 262.833 179.668 239.748 1.00 50.27  ? 39  PHE   A CZ    1 
ATOM   750  N N     . TYR   D 2 28  ? 258.332 176.728 241.112 1.00 52.00  ? 40  TYR   A N     1 
ATOM   751  C CA    . TYR   D 2 28  ? 258.433 176.778 242.567 1.00 52.17  ? 40  TYR   A CA    1 
ATOM   752  C C     . TYR   D 2 28  ? 258.682 175.391 243.146 1.00 49.97  ? 40  TYR   A C     1 
ATOM   753  O O     . TYR   D 2 28  ? 259.466 175.234 244.088 1.00 49.55  ? 40  TYR   A O     1 
ATOM   754  C CB    . TYR   D 2 28  ? 257.174 177.392 243.174 1.00 52.02  ? 40  TYR   A CB    1 
ATOM   755  C CG    . TYR   D 2 28  ? 257.342 177.761 244.629 1.00 51.01  ? 40  TYR   A CG    1 
ATOM   756  C CD1   . TYR   D 2 28  ? 258.014 178.915 244.996 1.00 49.59  ? 40  TYR   A CD1   1 
ATOM   757  C CD2   . TYR   D 2 28  ? 256.842 176.948 245.634 1.00 49.55  ? 40  TYR   A CD2   1 
ATOM   758  C CE1   . TYR   D 2 28  ? 258.177 179.253 246.320 1.00 50.83  ? 40  TYR   A CE1   1 
ATOM   759  C CE2   . TYR   D 2 28  ? 257.000 177.280 246.963 1.00 47.53  ? 40  TYR   A CE2   1 
ATOM   760  C CZ    . TYR   D 2 28  ? 257.669 178.434 247.298 1.00 48.38  ? 40  TYR   A CZ    1 
ATOM   761  O OH    . TYR   D 2 28  ? 257.831 178.773 248.617 1.00 51.20  ? 40  TYR   A OH    1 
ATOM   762  N N     . ILE   D 2 29  ? 258.017 174.374 242.597 1.00 50.54  ? 41  ILE   A N     1 
ATOM   763  C CA    . ILE   D 2 29  ? 258.242 173.008 243.065 1.00 48.99  ? 41  ILE   A CA    1 
ATOM   764  C C     . ILE   D 2 29  ? 259.691 172.590 242.833 1.00 49.92  ? 41  ILE   A C     1 
ATOM   765  O O     . ILE   D 2 29  ? 260.334 171.999 243.713 1.00 46.61  ? 41  ILE   A O     1 
ATOM   766  C CB    . ILE   D 2 29  ? 257.256 172.039 242.387 1.00 48.53  ? 41  ILE   A CB    1 
ATOM   767  C CG1   . ILE   D 2 29  ? 255.821 172.415 242.741 1.00 49.17  ? 41  ILE   A CG1   1 
ATOM   768  C CG2   . ILE   D 2 29  ? 257.535 170.613 242.811 1.00 52.92  ? 41  ILE   A CG2   1 
ATOM   769  C CD1   . ILE   D 2 29  ? 254.797 171.697 241.917 1.00 50.75  ? 41  ILE   A CD1   1 
ATOM   770  N N     . GLN   D 2 30  ? 260.230 172.894 241.648 1.00 52.22  ? 42  GLN   A N     1 
ATOM   771  C CA    . GLN   D 2 30  ? 261.619 172.542 241.359 1.00 49.69  ? 42  GLN   A CA    1 
ATOM   772  C C     . GLN   D 2 30  ? 262.582 173.272 242.288 1.00 49.92  ? 42  GLN   A C     1 
ATOM   773  O O     . GLN   D 2 30  ? 263.561 172.687 242.768 1.00 51.11  ? 42  GLN   A O     1 
ATOM   774  C CB    . GLN   D 2 30  ? 261.945 172.850 239.897 1.00 47.02  ? 42  GLN   A CB    1 
ATOM   775  C CG    . GLN   D 2 30  ? 263.380 172.545 239.500 1.00 48.35  ? 42  GLN   A CG    1 
ATOM   776  C CD    . GLN   D 2 30  ? 263.670 171.059 239.432 1.00 53.63  ? 42  GLN   A CD    1 
ATOM   777  O OE1   . GLN   D 2 30  ? 262.756 170.238 239.402 1.00 62.22  ? 42  GLN   A OE1   1 
ATOM   778  N NE2   . GLN   D 2 30  ? 264.949 170.707 239.406 1.00 44.12  ? 42  GLN   A NE2   1 
ATOM   779  N N     . MET   D 2 31  ? 262.322 174.553 242.552 1.00 49.47  ? 43  MET   A N     1 
ATOM   780  C CA    . MET   D 2 31  ? 263.182 175.314 243.451 1.00 49.98  ? 43  MET   A CA    1 
ATOM   781  C C     . MET   D 2 31  ? 263.127 174.762 244.869 1.00 50.93  ? 43  MET   A C     1 
ATOM   782  O O     . MET   D 2 31  ? 264.153 174.698 245.555 1.00 52.18  ? 43  MET   A O     1 
ATOM   783  C CB    . MET   D 2 31  ? 262.786 176.788 243.432 1.00 53.31  ? 43  MET   A CB    1 
ATOM   784  C CG    . MET   D 2 31  ? 263.575 177.629 242.449 1.00 56.69  ? 43  MET   A CG    1 
ATOM   785  S SD    . MET   D 2 31  ? 265.222 178.046 243.045 1.00 67.88  ? 43  MET   A SD    1 
ATOM   786  C CE    . MET   D 2 31  ? 266.228 177.002 242.004 1.00 60.99  ? 43  MET   A CE    1 
ATOM   787  N N     . CYS   D 2 32  ? 261.939 174.363 245.325 1.00 51.62  ? 44  CYS   A N     1 
ATOM   788  C CA    . CYS   D 2 32  ? 261.814 173.771 246.651 1.00 49.59  ? 44  CYS   A CA    1 
ATOM   789  C C     . CYS   D 2 32  ? 262.562 172.447 246.734 1.00 48.80  ? 44  CYS   A C     1 
ATOM   790  O O     . CYS   D 2 32  ? 263.156 172.123 247.768 1.00 44.34  ? 44  CYS   A O     1 
ATOM   791  C CB    . CYS   D 2 32  ? 260.340 173.578 247.000 1.00 50.73  ? 44  CYS   A CB    1 
ATOM   792  S SG    . CYS   D 2 32  ? 259.562 175.014 247.755 1.00 65.87  ? 44  CYS   A SG    1 
ATOM   793  N N     . THR   D 2 33  ? 262.525 171.658 245.658 1.00 52.05  ? 45  THR   A N     1 
ATOM   794  C CA    . THR   D 2 33  ? 263.291 170.416 245.630 1.00 49.51  ? 45  THR   A CA    1 
ATOM   795  C C     . THR   D 2 33  ? 264.790 170.691 245.677 1.00 50.65  ? 45  THR   A C     1 
ATOM   796  O O     . THR   D 2 33  ? 265.536 170.001 246.381 1.00 49.74  ? 45  THR   A O     1 
ATOM   797  C CB    . THR   D 2 33  ? 262.928 169.607 244.383 1.00 50.41  ? 45  THR   A CB    1 
ATOM   798  O OG1   . THR   D 2 33  ? 261.643 169.000 244.563 1.00 51.10  ? 45  THR   A OG1   1 
ATOM   799  C CG2   . THR   D 2 33  ? 263.954 168.521 244.123 1.00 51.35  ? 45  THR   A CG2   1 
ATOM   800  N N     . GLU   D 2 34  ? 265.249 171.705 244.941 1.00 52.77  ? 46  GLU   A N     1 
ATOM   801  C CA    . GLU   D 2 34  ? 266.676 172.003 244.896 1.00 53.69  ? 46  GLU   A CA    1 
ATOM   802  C C     . GLU   D 2 34  ? 267.180 172.679 246.165 1.00 53.21  ? 46  GLU   A C     1 
ATOM   803  O O     . GLU   D 2 34  ? 268.378 172.610 246.452 1.00 53.43  ? 46  GLU   A O     1 
ATOM   804  C CB    . GLU   D 2 34  ? 266.995 172.877 243.684 1.00 55.83  ? 46  GLU   A CB    1 
ATOM   805  C CG    . GLU   D 2 34  ? 267.149 172.094 242.397 1.00 60.04  ? 46  GLU   A CG    1 
ATOM   806  C CD    . GLU   D 2 34  ? 268.511 172.275 241.769 1.00 64.42  ? 46  GLU   A CD    1 
ATOM   807  O OE1   . GLU   D 2 34  ? 269.327 173.036 242.328 1.00 68.04  ? 46  GLU   A OE1   1 
ATOM   808  O OE2   . GLU   D 2 34  ? 268.772 171.651 240.722 1.00 67.29  ? 46  GLU   A OE2   1 
ATOM   809  N N     . LEU   D 2 35  ? 266.304 173.327 246.926 1.00 54.58  ? 47  LEU   A N     1 
ATOM   810  C CA    . LEU   D 2 35  ? 266.692 173.990 248.164 1.00 52.94  ? 47  LEU   A CA    1 
ATOM   811  C C     . LEU   D 2 35  ? 266.543 173.099 249.390 1.00 53.56  ? 47  LEU   A C     1 
ATOM   812  O O     . LEU   D 2 35  ? 266.912 173.524 250.490 1.00 54.07  ? 47  LEU   A O     1 
ATOM   813  C CB    . LEU   D 2 35  ? 265.870 175.268 248.355 1.00 54.47  ? 47  LEU   A CB    1 
ATOM   814  C CG    . LEU   D 2 35  ? 266.237 176.458 247.470 1.00 52.78  ? 47  LEU   A CG    1 
ATOM   815  C CD1   . LEU   D 2 35  ? 265.467 177.688 247.892 1.00 52.57  ? 47  LEU   A CD1   1 
ATOM   816  C CD2   . LEU   D 2 35  ? 267.721 176.719 247.554 1.00 49.81  ? 47  LEU   A CD2   1 
ATOM   817  N N     . LYS   D 2 36  ? 266.022 171.882 249.225 1.00 54.98  ? 48  LYS   A N     1 
ATOM   818  C CA    . LYS   D 2 36  ? 265.807 170.943 250.330 1.00 53.85  ? 48  LYS   A CA    1 
ATOM   819  C C     . LYS   D 2 36  ? 264.879 171.528 251.392 1.00 55.55  ? 48  LYS   A C     1 
ATOM   820  O O     . LYS   D 2 36  ? 265.078 171.335 252.592 1.00 60.10  ? 48  LYS   A O     1 
ATOM   821  C CB    . LYS   D 2 36  ? 267.131 170.502 250.956 1.00 51.39  ? 48  LYS   A CB    1 
ATOM   822  C CG    . LYS   D 2 36  ? 268.127 169.941 249.965 1.00 49.82  ? 48  LYS   A CG    1 
ATOM   823  C CD    . LYS   D 2 36  ? 268.149 168.429 250.002 1.00 47.04  ? 48  LYS   A CD    1 
ATOM   824  C CE    . LYS   D 2 36  ? 269.573 167.914 250.000 1.00 53.00  ? 48  LYS   A CE    1 
ATOM   825  N NZ    . LYS   D 2 36  ? 270.409 168.626 249.000 1.00 53.98  ? 48  LYS   A NZ    1 
ATOM   826  N N     . LEU   D 2 37  ? 263.854 172.245 250.948 1.00 55.96  ? 49  LEU   A N     1 
ATOM   827  C CA    . LEU   D 2 37  ? 262.866 172.793 251.864 1.00 57.13  ? 49  LEU   A CA    1 
ATOM   828  C C     . LEU   D 2 37  ? 261.798 171.755 252.175 1.00 58.48  ? 49  LEU   A C     1 
ATOM   829  O O     . LEU   D 2 37  ? 261.371 171.000 251.297 1.00 63.99  ? 49  LEU   A O     1 
ATOM   830  C CB    . LEU   D 2 37  ? 262.215 174.040 251.270 1.00 54.80  ? 49  LEU   A CB    1 
ATOM   831  C CG    . LEU   D 2 37  ? 263.129 175.211 250.922 1.00 53.87  ? 49  LEU   A CG    1 
ATOM   832  C CD1   . LEU   D 2 37  ? 262.399 176.194 250.030 1.00 53.54  ? 49  LEU   A CD1   1 
ATOM   833  C CD2   . LEU   D 2 37  ? 263.621 175.893 252.181 1.00 55.68  ? 49  LEU   A CD2   1 
ATOM   834  N N     . SER   D 2 38  ? 261.365 171.720 253.430 1.00 56.04  ? 50  SER   A N     1 
ATOM   835  C CA    . SER   D 2 38  ? 260.254 170.867 253.813 1.00 57.27  ? 50  SER   A CA    1 
ATOM   836  C C     . SER   D 2 38  ? 258.941 171.508 253.372 1.00 60.15  ? 50  SER   A C     1 
ATOM   837  O O     . SER   D 2 38  ? 258.915 172.580 252.763 1.00 61.52  ? 50  SER   A O     1 
ATOM   838  C CB    . SER   D 2 38  ? 260.272 170.610 255.317 1.00 59.04  ? 50  SER   A CB    1 
ATOM   839  O OG    . SER   D 2 38  ? 259.994 171.795 256.038 1.00 68.03  ? 50  SER   A OG    1 
ATOM   840  N N     . ASP   D 2 39  ? 257.829 170.836 253.675 1.00 58.47  ? 51  ASP   A N     1 
ATOM   841  C CA    . ASP   D 2 39  ? 256.526 171.351 253.266 1.00 58.38  ? 51  ASP   A CA    1 
ATOM   842  C C     . ASP   D 2 39  ? 256.212 172.670 253.960 1.00 59.23  ? 51  ASP   A C     1 
ATOM   843  O O     . ASP   D 2 39  ? 255.792 173.639 253.315 1.00 61.38  ? 51  ASP   A O     1 
ATOM   844  C CB    . ASP   D 2 39  ? 255.441 170.318 253.562 1.00 58.98  ? 51  ASP   A CB    1 
ATOM   845  C CG    . ASP   D 2 39  ? 254.386 170.261 252.483 1.00 65.88  ? 51  ASP   A CG    1 
ATOM   846  O OD1   . ASP   D 2 39  ? 254.755 170.221 251.292 1.00 71.16  ? 51  ASP   A OD1   1 
ATOM   847  O OD2   . ASP   D 2 39  ? 253.186 170.257 252.824 1.00 67.27  ? 51  ASP   A OD2   1 
ATOM   848  N N     . TYR   D 2 40  ? 256.429 172.728 255.275 1.00 60.11  ? 52  TYR   A N     1 
ATOM   849  C CA    . TYR   D 2 40  ? 256.191 173.960 256.018 1.00 57.93  ? 52  TYR   A CA    1 
ATOM   850  C C     . TYR   D 2 40  ? 257.083 175.082 255.506 1.00 57.81  ? 52  TYR   A C     1 
ATOM   851  O O     . TYR   D 2 40  ? 256.619 176.200 255.259 1.00 57.95  ? 52  TYR   A O     1 
ATOM   852  C CB    . TYR   D 2 40  ? 256.429 173.716 257.507 1.00 53.83  ? 52  TYR   A CB    1 
ATOM   853  C CG    . TYR   D 2 40  ? 255.834 174.758 258.423 1.00 53.08  ? 52  TYR   A CG    1 
ATOM   854  C CD1   . TYR   D 2 40  ? 256.357 176.041 258.484 1.00 54.10  ? 52  TYR   A CD1   1 
ATOM   855  C CD2   . TYR   D 2 40  ? 254.759 174.453 259.238 1.00 52.94  ? 52  TYR   A CD2   1 
ATOM   856  C CE1   . TYR   D 2 40  ? 255.818 176.990 259.321 1.00 54.14  ? 52  TYR   A CE1   1 
ATOM   857  C CE2   . TYR   D 2 40  ? 254.216 175.395 260.080 1.00 56.20  ? 52  TYR   A CE2   1 
ATOM   858  C CZ    . TYR   D 2 40  ? 254.748 176.662 260.118 1.00 54.65  ? 52  TYR   A CZ    1 
ATOM   859  O OH    . TYR   D 2 40  ? 254.204 177.602 260.956 1.00 56.73  ? 52  TYR   A OH    1 
ATOM   860  N N     . GLU   D 2 41  ? 258.373 174.795 255.333 1.00 56.81  ? 53  GLU   A N     1 
ATOM   861  C CA    . GLU   D 2 41  ? 259.298 175.810 254.849 1.00 53.75  ? 53  GLU   A CA    1 
ATOM   862  C C     . GLU   D 2 41  ? 258.993 176.200 253.410 1.00 53.79  ? 53  GLU   A C     1 
ATOM   863  O O     . GLU   D 2 41  ? 259.203 177.355 253.025 1.00 56.28  ? 53  GLU   A O     1 
ATOM   864  C CB    . GLU   D 2 41  ? 260.733 175.310 254.987 1.00 54.60  ? 53  GLU   A CB    1 
ATOM   865  C CG    . GLU   D 2 41  ? 261.141 175.046 256.423 1.00 57.00  ? 53  GLU   A CG    1 
ATOM   866  C CD    . GLU   D 2 41  ? 262.159 173.935 256.553 1.00 56.06  ? 53  GLU   A CD    1 
ATOM   867  O OE1   . GLU   D 2 41  ? 263.241 174.041 255.943 1.00 60.68  ? 53  GLU   A OE1   1 
ATOM   868  O OE2   . GLU   D 2 41  ? 261.883 172.956 257.272 1.00 55.24  ? 53  GLU   A OE2   1 
ATOM   869  N N     . GLY   D 2 42  ? 258.489 175.262 252.609 1.00 55.64  ? 54  GLY   A N     1 
ATOM   870  C CA    . GLY   D 2 42  ? 258.085 175.586 251.254 1.00 56.70  ? 54  GLY   A CA    1 
ATOM   871  C C     . GLY   D 2 42  ? 256.818 176.407 251.174 1.00 54.97  ? 54  GLY   A C     1 
ATOM   872  O O     . GLY   D 2 42  ? 256.596 177.087 250.167 1.00 55.68  ? 54  GLY   A O     1 
ATOM   873  N N     . ARG   D 2 43  ? 255.981 176.357 252.205 1.00 54.93  ? 55  ARG   A N     1 
ATOM   874  C CA    . ARG   D 2 43  ? 254.768 177.162 252.243 1.00 52.80  ? 55  ARG   A CA    1 
ATOM   875  C C     . ARG   D 2 43  ? 254.969 178.514 252.916 1.00 57.01  ? 55  ARG   A C     1 
ATOM   876  O O     . ARG   D 2 43  ? 254.016 179.293 253.001 1.00 58.33  ? 55  ARG   A O     1 
ATOM   877  C CB    . ARG   D 2 43  ? 253.648 176.395 252.951 1.00 48.66  ? 55  ARG   A CB    1 
ATOM   878  C CG    . ARG   D 2 43  ? 253.192 175.162 252.202 1.00 50.38  ? 55  ARG   A CG    1 
ATOM   879  C CD    . ARG   D 2 43  ? 252.265 174.309 253.039 1.00 55.70  ? 55  ARG   A CD    1 
ATOM   880  N NE    . ARG   D 2 43  ? 251.992 173.030 252.399 1.00 56.72  ? 55  ARG   A NE    1 
ATOM   881  C CZ    . ARG   D 2 43  ? 251.145 172.861 251.394 1.00 54.58  ? 55  ARG   A CZ    1 
ATOM   882  N NH1   . ARG   D 2 43  ? 250.456 173.873 250.895 1.00 50.95  ? 55  ARG   A NH1   1 
ATOM   883  N NH2   . ARG   D 2 43  ? 250.986 171.648 250.877 1.00 58.23  ? 55  ARG   A NH2   1 
ATOM   884  N N     . LEU   D 2 44  ? 256.175 178.811 253.392 1.00 57.10  ? 56  LEU   A N     1 
ATOM   885  C CA    . LEU   D 2 44  ? 256.441 180.103 254.008 1.00 51.56  ? 56  LEU   A CA    1 
ATOM   886  C C     . LEU   D 2 44  ? 256.457 181.194 252.946 1.00 52.81  ? 56  LEU   A C     1 
ATOM   887  O O     . LEU   D 2 44  ? 257.073 181.036 251.888 1.00 54.10  ? 56  LEU   A O     1 
ATOM   888  C CB    . LEU   D 2 44  ? 257.772 180.070 254.755 1.00 47.50  ? 56  LEU   A CB    1 
ATOM   889  C CG    . LEU   D 2 44  ? 257.868 180.901 256.033 1.00 48.87  ? 56  LEU   A CG    1 
ATOM   890  C CD1   . LEU   D 2 44  ? 257.097 180.237 257.154 1.00 55.66  ? 56  LEU   A CD1   1 
ATOM   891  C CD2   . LEU   D 2 44  ? 259.314 181.097 256.429 1.00 49.02  ? 56  LEU   A CD2   1 
ATOM   892  N N     . ILE   D 2 45  ? 255.776 182.305 253.230 1.00 50.94  ? 57  ILE   A N     1 
ATOM   893  C CA    . ILE   D 2 45  ? 255.677 183.383 252.252 1.00 48.13  ? 57  ILE   A CA    1 
ATOM   894  C C     . ILE   D 2 45  ? 257.027 184.061 252.045 1.00 48.01  ? 57  ILE   A C     1 
ATOM   895  O O     . ILE   D 2 45  ? 257.312 184.569 250.955 1.00 48.51  ? 57  ILE   A O     1 
ATOM   896  C CB    . ILE   D 2 45  ? 254.585 184.385 252.677 1.00 46.73  ? 57  ILE   A CB    1 
ATOM   897  C CG1   . ILE   D 2 45  ? 254.251 185.337 251.530 1.00 50.57  ? 57  ILE   A CG1   1 
ATOM   898  C CG2   . ILE   D 2 45  ? 255.002 185.158 253.914 1.00 50.96  ? 57  ILE   A CG2   1 
ATOM   899  C CD1   . ILE   D 2 45  ? 252.822 185.811 251.536 1.00 54.71  ? 57  ILE   A CD1   1 
ATOM   900  N N     . GLN   D 2 46  ? 257.882 184.072 253.070 1.00 48.76  ? 58  GLN   A N     1 
ATOM   901  C CA    . GLN   D 2 46  ? 259.185 184.718 252.941 1.00 50.43  ? 58  GLN   A CA    1 
ATOM   902  C C     . GLN   D 2 46  ? 260.103 183.934 252.010 1.00 53.58  ? 58  GLN   A C     1 
ATOM   903  O O     . GLN   D 2 46  ? 260.833 184.524 251.202 1.00 52.79  ? 58  GLN   A O     1 
ATOM   904  C CB    . GLN   D 2 46  ? 259.823 184.882 254.319 1.00 49.20  ? 58  GLN   A CB    1 
ATOM   905  C CG    . GLN   D 2 46  ? 259.385 186.132 255.060 1.00 49.10  ? 58  GLN   A CG    1 
ATOM   906  C CD    . GLN   D 2 46  ? 258.121 185.917 255.860 1.00 48.80  ? 58  GLN   A CD    1 
ATOM   907  O OE1   . GLN   D 2 46  ? 257.668 184.788 256.028 1.00 54.18  ? 58  GLN   A OE1   1 
ATOM   908  N NE2   . GLN   D 2 46  ? 257.545 187.000 256.360 1.00 46.55  ? 58  GLN   A NE2   1 
ATOM   909  N N     . ASN   D 2 47  ? 260.081 182.603 252.108 1.00 51.13  ? 59  ASN   A N     1 
ATOM   910  C CA    . ASN   D 2 47  ? 260.874 181.784 251.199 1.00 49.76  ? 59  ASN   A CA    1 
ATOM   911  C C     . ASN   D 2 47  ? 260.414 181.969 249.760 1.00 49.21  ? 59  ASN   A C     1 
ATOM   912  O O     . ASN   D 2 47  ? 261.237 182.039 248.838 1.00 49.52  ? 59  ASN   A O     1 
ATOM   913  C CB    . ASN   D 2 47  ? 260.791 180.311 251.600 1.00 50.76  ? 59  ASN   A CB    1 
ATOM   914  C CG    . ASN   D 2 47  ? 261.555 180.006 252.870 1.00 51.19  ? 59  ASN   A CG    1 
ATOM   915  O OD1   . ASN   D 2 47  ? 262.727 180.348 252.999 1.00 54.71  ? 59  ASN   A OD1   1 
ATOM   916  N ND2   . ASN   D 2 47  ? 260.899 179.339 253.807 1.00 54.06  ? 59  ASN   A ND2   1 
ATOM   917  N N     . SER   D 2 48  ? 259.098 182.042 249.547 1.00 48.28  ? 60  SER   A N     1 
ATOM   918  C CA    . SER   D 2 48  ? 258.584 182.282 248.204 1.00 49.70  ? 60  SER   A CA    1 
ATOM   919  C C     . SER   D 2 48  ? 259.000 183.655 247.697 1.00 48.87  ? 60  SER   A C     1 
ATOM   920  O O     . SER   D 2 48  ? 259.330 183.811 246.518 1.00 49.41  ? 60  SER   A O     1 
ATOM   921  C CB    . SER   D 2 48  ? 257.062 182.136 248.184 1.00 51.10  ? 60  SER   A CB    1 
ATOM   922  O OG    . SER   D 2 48  ? 256.429 183.309 248.655 1.00 56.75  ? 60  SER   A OG    1 
ATOM   923  N N     . LEU   D 2 49  ? 258.986 184.664 248.571 1.00 49.12  ? 61  LEU   A N     1 
ATOM   924  C CA    . LEU   D 2 49  ? 259.458 185.988 248.176 1.00 48.02  ? 61  LEU   A CA    1 
ATOM   925  C C     . LEU   D 2 49  ? 260.913 185.934 247.731 1.00 48.35  ? 61  LEU   A C     1 
ATOM   926  O O     . LEU   D 2 49  ? 261.280 186.512 246.700 1.00 49.45  ? 61  LEU   A O     1 
ATOM   927  C CB    . LEU   D 2 49  ? 259.289 186.970 249.336 1.00 48.17  ? 61  LEU   A CB    1 
ATOM   928  C CG    . LEU   D 2 49  ? 258.121 187.956 249.309 1.00 49.07  ? 61  LEU   A CG    1 
ATOM   929  C CD1   . LEU   D 2 49  ? 258.378 189.061 248.305 1.00 53.75  ? 61  LEU   A CD1   1 
ATOM   930  C CD2   . LEU   D 2 49  ? 256.820 187.245 249.000 1.00 53.48  ? 61  LEU   A CD2   1 
ATOM   931  N N     . THR   D 2 50  ? 261.749 185.223 248.491 1.00 48.61  ? 62  THR   A N     1 
ATOM   932  C CA    . THR   D 2 50  ? 263.158 185.086 248.132 1.00 47.49  ? 62  THR   A CA    1 
ATOM   933  C C     . THR   D 2 50  ? 263.319 184.400 246.779 1.00 45.81  ? 62  THR   A C     1 
ATOM   934  O O     . THR   D 2 50  ? 264.102 184.847 245.932 1.00 45.97  ? 62  THR   A O     1 
ATOM   935  C CB    . THR   D 2 50  ? 263.895 184.306 249.222 1.00 47.68  ? 62  THR   A CB    1 
ATOM   936  O OG1   . THR   D 2 50  ? 264.003 185.115 250.398 1.00 50.28  ? 62  THR   A OG1   1 
ATOM   937  C CG2   . THR   D 2 50  ? 265.281 183.916 248.759 1.00 51.21  ? 62  THR   A CG2   1 
ATOM   938  N N     . ILE   D 2 51  ? 262.574 183.317 246.556 1.00 46.59  ? 63  ILE   A N     1 
ATOM   939  C CA    . ILE   D 2 51  ? 262.694 182.571 245.306 1.00 48.32  ? 63  ILE   A CA    1 
ATOM   940  C C     . ILE   D 2 51  ? 262.242 183.418 244.120 1.00 46.76  ? 63  ILE   A C     1 
ATOM   941  O O     . ILE   D 2 51  ? 262.904 183.451 243.072 1.00 46.98  ? 63  ILE   A O     1 
ATOM   942  C CB    . ILE   D 2 51  ? 261.906 181.253 245.403 1.00 48.73  ? 63  ILE   A CB    1 
ATOM   943  C CG1   . ILE   D 2 51  ? 262.589 180.304 246.389 1.00 46.91  ? 63  ILE   A CG1   1 
ATOM   944  C CG2   . ILE   D 2 51  ? 261.774 180.605 244.038 1.00 51.07  ? 63  ILE   A CG2   1 
ATOM   945  C CD1   . ILE   D 2 51  ? 261.973 178.932 246.438 1.00 51.07  ? 63  ILE   A CD1   1 
ATOM   946  N N     . GLU   D 2 52  ? 261.118 184.124 244.266 1.00 46.51  ? 64  GLU   A N     1 
ATOM   947  C CA    . GLU   D 2 52  ? 260.642 184.992 243.195 1.00 45.10  ? 64  GLU   A CA    1 
ATOM   948  C C     . GLU   D 2 52  ? 261.651 186.089 242.888 1.00 46.24  ? 64  GLU   A C     1 
ATOM   949  O O     . GLU   D 2 52  ? 261.885 186.418 241.718 1.00 48.34  ? 64  GLU   A O     1 
ATOM   950  C CB    . GLU   D 2 52  ? 259.292 185.601 243.570 1.00 45.87  ? 64  GLU   A CB    1 
ATOM   951  C CG    . GLU   D 2 52  ? 258.186 184.592 243.792 1.00 45.55  ? 64  GLU   A CG    1 
ATOM   952  C CD    . GLU   D 2 52  ? 257.094 185.126 244.691 1.00 52.22  ? 64  GLU   A CD    1 
ATOM   953  O OE1   . GLU   D 2 52  ? 257.153 186.317 245.053 1.00 54.03  ? 64  GLU   A OE1   1 
ATOM   954  O OE2   . GLU   D 2 52  ? 256.179 184.357 245.043 1.00 57.54  ? 64  GLU   A OE2   1 
ATOM   955  N N     . ARG   D 2 53  ? 262.252 186.676 243.926 1.00 46.36  ? 65  ARG   A N     1 
ATOM   956  C CA    . ARG   D 2 53  ? 263.257 187.707 243.696 1.00 46.74  ? 65  ARG   A CA    1 
ATOM   957  C C     . ARG   D 2 53  ? 264.477 187.135 242.986 1.00 44.51  ? 65  ARG   A C     1 
ATOM   958  O O     . ARG   D 2 53  ? 265.086 187.809 242.148 1.00 45.24  ? 65  ARG   A O     1 
ATOM   959  C CB    . ARG   D 2 53  ? 263.648 188.362 245.017 1.00 46.81  ? 65  ARG   A CB    1 
ATOM   960  C CG    . ARG   D 2 53  ? 262.637 189.377 245.504 1.00 48.39  ? 65  ARG   A CG    1 
ATOM   961  C CD    . ARG   D 2 53  ? 262.709 189.554 247.003 1.00 52.43  ? 65  ARG   A CD    1 
ATOM   962  N NE    . ARG   D 2 53  ? 263.902 190.291 247.396 1.00 56.89  ? 65  ARG   A NE    1 
ATOM   963  C CZ    . ARG   D 2 53  ? 264.000 191.612 247.376 1.00 59.86  ? 65  ARG   A CZ    1 
ATOM   964  N NH1   . ARG   D 2 53  ? 262.991 192.374 246.990 1.00 57.53  ? 65  ARG   A NH1   1 
ATOM   965  N NH2   . ARG   D 2 53  ? 265.139 192.183 247.754 1.00 63.01  ? 65  ARG   A NH2   1 
ATOM   966  N N     . MET   D 2 54  ? 264.843 185.891 243.303 1.00 43.70  ? 66  MET   A N     1 
ATOM   967  C CA    . MET   D 2 54  ? 265.909 185.218 242.565 1.00 44.63  ? 66  MET   A CA    1 
ATOM   968  C C     . MET   D 2 54  ? 265.571 185.125 241.083 1.00 47.18  ? 66  MET   A C     1 
ATOM   969  O O     . MET   D 2 54  ? 266.415 185.407 240.221 1.00 49.26  ? 66  MET   A O     1 
ATOM   970  C CB    . MET   D 2 54  ? 266.145 183.821 243.130 1.00 46.02  ? 66  MET   A CB    1 
ATOM   971  C CG    . MET   D 2 54  ? 266.994 183.758 244.371 1.00 49.27  ? 66  MET   A CG    1 
ATOM   972  S SD    . MET   D 2 54  ? 266.995 182.080 245.017 1.00 62.63  ? 66  MET   A SD    1 
ATOM   973  C CE    . MET   D 2 54  ? 268.465 182.125 246.017 1.00 59.68  ? 66  MET   A CE    1 
ATOM   974  N N     . VAL   D 2 55  ? 264.335 184.728 240.770 1.00 47.53  ? 67  VAL   A N     1 
ATOM   975  C CA    . VAL   D 2 55  ? 263.929 184.629 239.367 1.00 44.08  ? 67  VAL   A CA    1 
ATOM   976  C C     . VAL   D 2 55  ? 264.035 185.985 238.691 1.00 47.54  ? 67  VAL   A C     1 
ATOM   977  O O     . VAL   D 2 55  ? 264.571 186.111 237.584 1.00 49.56  ? 67  VAL   A O     1 
ATOM   978  C CB    . VAL   D 2 55  ? 262.498 184.082 239.239 1.00 46.59  ? 67  VAL   A CB    1 
ATOM   979  C CG1   . VAL   D 2 55  ? 262.250 183.600 237.823 1.00 49.42  ? 67  VAL   A CG1   1 
ATOM   980  C CG2   . VAL   D 2 55  ? 262.254 183.007 240.221 1.00 52.84  ? 67  VAL   A CG2   1 
ATOM   981  N N     . LEU   D 2 56  ? 263.506 187.019 239.344 1.00 46.10  ? 68  LEU   A N     1 
ATOM   982  C CA    . LEU   D 2 56  ? 263.465 188.337 238.723 1.00 47.90  ? 68  LEU   A CA    1 
ATOM   983  C C     . LEU   D 2 56  ? 264.867 188.893 238.506 1.00 50.07  ? 68  LEU   A C     1 
ATOM   984  O O     . LEU   D 2 56  ? 265.142 189.507 237.469 1.00 52.73  ? 68  LEU   A O     1 
ATOM   985  C CB    . LEU   D 2 56  ? 262.625 189.288 239.573 1.00 50.45  ? 68  LEU   A CB    1 
ATOM   986  C CG    . LEU   D 2 56  ? 261.144 188.930 239.708 1.00 47.59  ? 68  LEU   A CG    1 
ATOM   987  C CD1   . LEU   D 2 56  ? 260.408 189.990 240.501 1.00 49.06  ? 68  LEU   A CD1   1 
ATOM   988  C CD2   . LEU   D 2 56  ? 260.513 188.755 238.343 1.00 47.67  ? 68  LEU   A CD2   1 
ATOM   989  N N     . SER   D 2 57  ? 265.769 188.679 239.466 1.00 48.81  ? 69  SER   A N     1 
ATOM   990  C CA    . SER   D 2 57  ? 267.129 189.187 239.331 1.00 48.75  ? 69  SER   A CA    1 
ATOM   991  C C     . SER   D 2 57  ? 267.935 188.395 238.312 1.00 47.90  ? 69  SER   A C     1 
ATOM   992  O O     . SER   D 2 57  ? 268.847 188.947 237.687 1.00 48.53  ? 69  SER   A O     1 
ATOM   993  C CB    . SER   D 2 57  ? 267.822 189.179 240.690 1.00 50.04  ? 69  SER   A CB    1 
ATOM   994  O OG    . SER   D 2 57  ? 267.652 187.929 241.331 1.00 59.29  ? 69  SER   A OG    1 
ATOM   995  N N     . ALA   D 2 58  ? 267.628 187.108 238.131 1.00 48.03  ? 70  ALA   A N     1 
ATOM   996  C CA    . ALA   D 2 58  ? 268.319 186.337 237.103 1.00 48.68  ? 70  ALA   A CA    1 
ATOM   997  C C     . ALA   D 2 58  ? 267.976 186.839 235.705 1.00 48.59  ? 70  ALA   A C     1 
ATOM   998  O O     . ALA   D 2 58  ? 268.845 186.895 234.828 1.00 48.68  ? 70  ALA   A O     1 
ATOM   999  C CB    . ALA   D 2 58  ? 267.981 184.855 237.237 1.00 48.57  ? 70  ALA   A CB    1 
ATOM   1000 N N     . PHE   D 2 59  ? 266.720 187.211 235.478 1.00 50.67  ? 71  PHE   A N     1 
ATOM   1001 C CA    . PHE   D 2 59  ? 266.253 187.620 234.162 1.00 49.52  ? 71  PHE   A CA    1 
ATOM   1002 C C     . PHE   D 2 59  ? 266.286 189.129 233.952 1.00 55.34  ? 71  PHE   A C     1 
ATOM   1003 O O     . PHE   D 2 59  ? 265.825 189.603 232.911 1.00 62.17  ? 71  PHE   A O     1 
ATOM   1004 C CB    . PHE   D 2 59  ? 264.840 187.088 233.921 1.00 48.04  ? 71  PHE   A CB    1 
ATOM   1005 C CG    . PHE   D 2 59  ? 264.810 185.664 233.462 1.00 49.29  ? 71  PHE   A CG    1 
ATOM   1006 C CD1   . PHE   D 2 59  ? 265.013 185.349 232.131 1.00 46.96  ? 71  PHE   A CD1   1 
ATOM   1007 C CD2   . PHE   D 2 59  ? 264.595 184.638 234.361 1.00 51.43  ? 71  PHE   A CD2   1 
ATOM   1008 C CE1   . PHE   D 2 59  ? 264.996 184.040 231.708 1.00 47.96  ? 71  PHE   A CE1   1 
ATOM   1009 C CE2   . PHE   D 2 59  ? 264.578 183.328 233.941 1.00 51.13  ? 71  PHE   A CE2   1 
ATOM   1010 C CZ    . PHE   D 2 59  ? 264.779 183.029 232.614 1.00 50.11  ? 71  PHE   A CZ    1 
ATOM   1011 N N     . ASP   D 2 60  ? 266.817 189.889 234.906 1.00 53.84  ? 72  ASP   A N     1 
ATOM   1012 C CA    . ASP   D 2 60  ? 267.000 191.330 234.737 1.00 55.72  ? 72  ASP   A CA    1 
ATOM   1013 C C     . ASP   D 2 60  ? 268.245 191.539 233.886 1.00 59.01  ? 72  ASP   A C     1 
ATOM   1014 O O     . ASP   D 2 60  ? 269.347 191.744 234.395 1.00 63.31  ? 72  ASP   A O     1 
ATOM   1015 C CB    . ASP   D 2 60  ? 267.115 192.021 236.090 1.00 55.43  ? 72  ASP   A CB    1 
ATOM   1016 C CG    . ASP   D 2 60  ? 267.014 193.527 235.986 1.00 60.62  ? 72  ASP   A CG    1 
ATOM   1017 O OD1   . ASP   D 2 60  ? 266.980 194.049 234.855 1.00 60.57  ? 72  ASP   A OD1   1 
ATOM   1018 O OD2   . ASP   D 2 60  ? 266.965 194.192 237.041 1.00 64.71  ? 72  ASP   A OD2   1 
ATOM   1019 N N     . GLU   D 2 61  ? 268.060 191.496 232.566 1.00 57.19  ? 73  GLU   A N     1 
ATOM   1020 C CA    . GLU   D 2 61  ? 269.196 191.436 231.650 1.00 57.47  ? 73  GLU   A CA    1 
ATOM   1021 C C     . GLU   D 2 61  ? 270.071 192.680 231.756 1.00 59.61  ? 73  GLU   A C     1 
ATOM   1022 O O     . GLU   D 2 61  ? 271.301 192.582 231.847 1.00 61.63  ? 73  GLU   A O     1 
ATOM   1023 C CB    . GLU   D 2 61  ? 268.693 191.252 230.216 1.00 59.27  ? 73  GLU   A CB    1 
ATOM   1024 C CG    . GLU   D 2 61  ? 269.133 189.972 229.488 1.00 69.92  ? 73  GLU   A CG    1 
ATOM   1025 C CD    . GLU   D 2 61  ? 270.639 189.699 229.462 1.00 85.52  ? 73  GLU   A CD    1 
ATOM   1026 O OE1   . GLU   D 2 61  ? 271.440 190.436 230.073 1.00 81.11  ? 73  GLU   A OE1   1 
ATOM   1027 O OE2   . GLU   D 2 61  ? 271.027 188.708 228.811 1.00 94.69  ? 73  GLU   A OE2   1 
ATOM   1028 N N     . ARG   D 2 62  ? 269.455 193.864 231.748 1.00 58.84  ? 74  ARG   A N     1 
ATOM   1029 C CA    . ARG   D 2 62  ? 270.240 195.094 231.742 1.00 56.87  ? 74  ARG   A CA    1 
ATOM   1030 C C     . ARG   D 2 62  ? 271.006 195.271 233.044 1.00 57.65  ? 74  ARG   A C     1 
ATOM   1031 O O     . ARG   D 2 62  ? 272.175 195.675 233.033 1.00 58.95  ? 74  ARG   A O     1 
ATOM   1032 C CB    . ARG   D 2 62  ? 269.336 196.295 231.480 1.00 57.98  ? 74  ARG   A CB    1 
ATOM   1033 C CG    . ARG   D 2 62  ? 268.516 196.160 230.220 1.00 60.20  ? 74  ARG   A CG    1 
ATOM   1034 C CD    . ARG   D 2 62  ? 269.125 196.954 229.086 1.00 60.88  ? 74  ARG   A CD    1 
ATOM   1035 N NE    . ARG   D 2 62  ? 268.367 196.787 227.855 1.00 61.05  ? 74  ARG   A NE    1 
ATOM   1036 C CZ    . ARG   D 2 62  ? 267.397 197.597 227.461 1.00 74.70  ? 74  ARG   A CZ    1 
ATOM   1037 N NH1   . ARG   D 2 62  ? 267.090 198.687 228.143 1.00 81.84  ? 74  ARG   A NH1   1 
ATOM   1038 N NH2   . ARG   D 2 62  ? 266.725 197.313 226.350 1.00 82.29  ? 74  ARG   A NH2   1 
ATOM   1039 N N     . ARG   D 2 63  ? 270.368 194.973 234.176 1.00 57.77  ? 75  ARG   A N     1 
ATOM   1040 C CA    . ARG   D 2 63  ? 271.069 195.061 235.451 1.00 55.81  ? 75  ARG   A CA    1 
ATOM   1041 C C     . ARG   D 2 63  ? 272.199 194.045 235.525 1.00 55.66  ? 75  ARG   A C     1 
ATOM   1042 O O     . ARG   D 2 63  ? 273.269 194.341 236.062 1.00 58.89  ? 75  ARG   A O     1 
ATOM   1043 C CB    . ARG   D 2 63  ? 270.097 194.867 236.611 1.00 57.43  ? 75  ARG   A CB    1 
ATOM   1044 C CG    . ARG   D 2 63  ? 270.787 194.619 237.932 1.00 56.93  ? 75  ARG   A CG    1 
ATOM   1045 C CD    . ARG   D 2 63  ? 269.974 195.131 239.095 1.00 53.92  ? 75  ARG   A CD    1 
ATOM   1046 N NE    . ARG   D 2 63  ? 270.801 195.292 240.283 1.00 54.75  ? 75  ARG   A NE    1 
ATOM   1047 C CZ    . ARG   D 2 63  ? 271.227 194.292 241.041 1.00 58.70  ? 75  ARG   A CZ    1 
ATOM   1048 N NH1   . ARG   D 2 63  ? 270.908 193.037 240.773 1.00 55.11  ? 75  ARG   A NH1   1 
ATOM   1049 N NH2   . ARG   D 2 63  ? 271.994 194.558 242.093 1.00 64.32  ? 75  ARG   A NH2   1 
ATOM   1050 N N     . ASN   D 2 64  ? 271.979 192.838 235.000 1.00 53.04  ? 76  ASN   A N     1 
ATOM   1051 C CA    . ASN   D 2 64  ? 273.042 191.838 234.998 1.00 55.19  ? 76  ASN   A CA    1 
ATOM   1052 C C     . ASN   D 2 64  ? 274.231 192.303 234.170 1.00 58.64  ? 76  ASN   A C     1 
ATOM   1053 O O     . ASN   D 2 64  ? 275.386 192.152 234.586 1.00 63.20  ? 76  ASN   A O     1 
ATOM   1054 C CB    . ASN   D 2 64  ? 272.514 190.506 234.469 1.00 54.77  ? 76  ASN   A CB    1 
ATOM   1055 C CG    . ASN   D 2 64  ? 271.464 189.898 235.369 1.00 53.48  ? 76  ASN   A CG    1 
ATOM   1056 O OD1   . ASN   D 2 64  ? 271.234 190.368 236.480 1.00 57.88  ? 76  ASN   A OD1   1 
ATOM   1057 N ND2   . ASN   D 2 64  ? 270.818 188.845 234.891 1.00 52.26  ? 76  ASN   A ND2   1 
ATOM   1058 N N     . LYS   D 2 65  ? 273.967 192.881 232.996 1.00 53.97  ? 77  LYS   A N     1 
ATOM   1059 C CA    . LYS   D 2 65  ? 275.050 193.391 232.163 1.00 58.29  ? 77  LYS   A CA    1 
ATOM   1060 C C     . LYS   D 2 65  ? 275.793 194.526 232.858 1.00 61.79  ? 77  LYS   A C     1 
ATOM   1061 O O     . LYS   D 2 65  ? 277.030 194.572 232.844 1.00 64.80  ? 77  LYS   A O     1 
ATOM   1062 C CB    . LYS   D 2 65  ? 274.492 193.844 230.816 1.00 61.32  ? 77  LYS   A CB    1 
ATOM   1063 C CG    . LYS   D 2 65  ? 275.355 194.849 230.083 1.00 72.94  ? 77  LYS   A CG    1 
ATOM   1064 C CD    . LYS   D 2 65  ? 274.995 194.897 228.612 1.00 68.67  ? 77  LYS   A CD    1 
ATOM   1065 C CE    . LYS   D 2 65  ? 275.092 193.520 227.988 1.00 73.11  ? 77  LYS   A CE    1 
ATOM   1066 N NZ    . LYS   D 2 65  ? 276.395 192.871 228.293 1.00 76.73  ? 77  LYS   A NZ    1 
ATOM   1067 N N     . TYR   D 2 66  ? 275.054 195.444 233.485 1.00 57.98  ? 78  TYR   A N     1 
ATOM   1068 C CA    . TYR   D 2 66  ? 275.689 196.533 234.221 1.00 57.05  ? 78  TYR   A CA    1 
ATOM   1069 C C     . TYR   D 2 66  ? 276.544 196.000 235.363 1.00 57.40  ? 78  TYR   A C     1 
ATOM   1070 O O     . TYR   D 2 66  ? 277.659 196.482 235.593 1.00 60.96  ? 78  TYR   A O     1 
ATOM   1071 C CB    . TYR   D 2 66  ? 274.620 197.492 234.743 1.00 59.02  ? 78  TYR   A CB    1 
ATOM   1072 C CG    . TYR   D 2 66  ? 275.114 198.509 235.743 1.00 59.90  ? 78  TYR   A CG    1 
ATOM   1073 C CD1   . TYR   D 2 66  ? 276.241 199.275 235.489 1.00 63.23  ? 78  TYR   A CD1   1 
ATOM   1074 C CD2   . TYR   D 2 66  ? 274.443 198.713 236.938 1.00 58.80  ? 78  TYR   A CD2   1 
ATOM   1075 C CE1   . TYR   D 2 66  ? 276.690 200.205 236.401 1.00 63.17  ? 78  TYR   A CE1   1 
ATOM   1076 C CE2   . TYR   D 2 66  ? 274.883 199.640 237.853 1.00 60.96  ? 78  TYR   A CE2   1 
ATOM   1077 C CZ    . TYR   D 2 66  ? 276.007 200.384 237.581 1.00 66.63  ? 78  TYR   A CZ    1 
ATOM   1078 O OH    . TYR   D 2 66  ? 276.450 201.311 238.493 1.00 82.37  ? 78  TYR   A OH    1 
ATOM   1079 N N     . LEU   D 2 67  ? 276.039 195.002 236.089 1.00 56.09  ? 79  LEU   A N     1 
ATOM   1080 C CA    . LEU   D 2 67  ? 276.796 194.414 237.187 1.00 57.22  ? 79  LEU   A CA    1 
ATOM   1081 C C     . LEU   D 2 67  ? 278.067 193.753 236.682 1.00 58.47  ? 79  LEU   A C     1 
ATOM   1082 O O     . LEU   D 2 67  ? 279.114 193.822 237.335 1.00 62.45  ? 79  LEU   A O     1 
ATOM   1083 C CB    . LEU   D 2 67  ? 275.929 193.404 237.936 1.00 57.41  ? 79  LEU   A CB    1 
ATOM   1084 C CG    . LEU   D 2 67  ? 274.900 193.974 238.909 1.00 56.03  ? 79  LEU   A CG    1 
ATOM   1085 C CD1   . LEU   D 2 67  ? 274.268 192.856 239.711 1.00 54.98  ? 79  LEU   A CD1   1 
ATOM   1086 C CD2   . LEU   D 2 67  ? 275.544 194.994 239.826 1.00 60.33  ? 79  LEU   A CD2   1 
ATOM   1087 N N     . GLU   D 2 68  ? 277.994 193.091 235.527 1.00 60.41  ? 80  GLU   A N     1 
ATOM   1088 C CA    . GLU   D 2 68  ? 279.202 192.524 234.941 1.00 63.01  ? 80  GLU   A CA    1 
ATOM   1089 C C     . GLU   D 2 68  ? 280.208 193.613 234.597 1.00 64.95  ? 80  GLU   A C     1 
ATOM   1090 O O     . GLU   D 2 68  ? 281.402 193.476 234.882 1.00 67.74  ? 80  GLU   A O     1 
ATOM   1091 C CB    . GLU   D 2 68  ? 278.853 191.701 233.704 1.00 62.15  ? 80  GLU   A CB    1 
ATOM   1092 C CG    . GLU   D 2 68  ? 277.986 190.496 233.999 1.00 63.52  ? 80  GLU   A CG    1 
ATOM   1093 C CD    . GLU   D 2 68  ? 278.084 189.437 232.928 1.00 79.84  ? 80  GLU   A CD    1 
ATOM   1094 O OE1   . GLU   D 2 68  ? 279.215 189.135 232.496 1.00 90.06  ? 80  GLU   A OE1   1 
ATOM   1095 O OE2   . GLU   D 2 68  ? 277.033 188.905 232.517 1.00 86.99  ? 80  GLU   A OE2   1 
ATOM   1096 N N     . GLU   D 2 69  ? 279.744 194.709 233.994 1.00 66.17  ? 81  GLU   A N     1 
ATOM   1097 C CA    . GLU   D 2 69  ? 280.658 195.792 233.641 1.00 68.15  ? 81  GLU   A CA    1 
ATOM   1098 C C     . GLU   D 2 69  ? 281.190 196.498 234.885 1.00 64.12  ? 81  GLU   A C     1 
ATOM   1099 O O     . GLU   D 2 69  ? 282.395 196.750 234.999 1.00 59.80  ? 81  GLU   A O     1 
ATOM   1100 C CB    . GLU   D 2 69  ? 279.957 196.786 232.712 1.00 74.38  ? 81  GLU   A CB    1 
ATOM   1101 C CG    . GLU   D 2 69  ? 279.343 196.255 231.386 1.00 81.23  ? 81  GLU   A CG    1 
ATOM   1102 C CD    . GLU   D 2 69  ? 280.042 195.064 230.705 1.00 96.36  ? 81  GLU   A CD    1 
ATOM   1103 O OE1   . GLU   D 2 69  ? 281.159 194.650 231.081 1.00 97.33  ? 81  GLU   A OE1   1 
ATOM   1104 O OE2   . GLU   D 2 69  ? 279.438 194.526 229.753 1.00 100.61 ? 81  GLU   A OE2   1 
ATOM   1105 N N     . HIS   D 2 70  ? 280.307 196.820 235.830 1.00 64.02  ? 82  HIS   A N     1 
ATOM   1106 C CA    . HIS   D 2 70  ? 280.673 197.487 237.080 1.00 61.30  ? 82  HIS   A CA    1 
ATOM   1107 C C     . HIS   D 2 70  ? 280.347 196.538 238.224 1.00 65.41  ? 82  HIS   A C     1 
ATOM   1108 O O     . HIS   D 2 70  ? 279.202 196.498 238.701 1.00 66.96  ? 82  HIS   A O     1 
ATOM   1109 C CB    . HIS   D 2 70  ? 279.935 198.814 237.245 1.00 60.62  ? 82  HIS   A CB    1 
ATOM   1110 C CG    . HIS   D 2 70  ? 280.091 199.748 236.087 1.00 64.74  ? 82  HIS   A CG    1 
ATOM   1111 N ND1   . HIS   D 2 70  ? 279.748 199.403 234.798 1.00 66.70  ? 82  HIS   A ND1   1 
ATOM   1112 C CD2   . HIS   D 2 70  ? 280.546 201.021 236.025 1.00 70.32  ? 82  HIS   A CD2   1 
ATOM   1113 C CE1   . HIS   D 2 70  ? 279.991 200.420 233.991 1.00 69.01  ? 82  HIS   A CE1   1 
ATOM   1114 N NE2   . HIS   D 2 70  ? 280.475 201.415 234.711 1.00 73.73  ? 82  HIS   A NE2   1 
ATOM   1115 N N     . PRO   D 2 71  ? 281.314 195.754 238.693 1.00 68.34  ? 83  PRO   A N     1 
ATOM   1116 C CA    . PRO   D 2 71  ? 281.021 194.782 239.749 1.00 64.80  ? 83  PRO   A CA    1 
ATOM   1117 C C     . PRO   D 2 71  ? 280.630 195.465 241.048 1.00 63.98  ? 83  PRO   A C     1 
ATOM   1118 O O     . PRO   D 2 71  ? 281.071 196.573 241.357 1.00 60.41  ? 83  PRO   A O     1 
ATOM   1119 C CB    . PRO   D 2 71  ? 282.330 193.999 239.907 1.00 58.66  ? 83  PRO   A CB    1 
ATOM   1120 C CG    . PRO   D 2 71  ? 283.361 194.743 239.168 1.00 61.32  ? 83  PRO   A CG    1 
ATOM   1121 C CD    . PRO   D 2 71  ? 282.727 195.757 238.283 1.00 70.60  ? 83  PRO   A CD    1 
ATOM   1122 N N     . SER   D 2 72  ? 279.777 194.785 241.806 1.00 65.80  ? 84  SER   A N     1 
ATOM   1123 C CA    . SER   D 2 72  ? 279.365 195.269 243.110 1.00 65.08  ? 84  SER   A CA    1 
ATOM   1124 C C     . SER   D 2 72  ? 280.447 194.970 244.147 1.00 66.12  ? 84  SER   A C     1 
ATOM   1125 O O     . SER   D 2 72  ? 281.406 194.238 243.894 1.00 68.53  ? 84  SER   A O     1 
ATOM   1126 C CB    . SER   D 2 72  ? 278.034 194.640 243.513 1.00 63.71  ? 84  SER   A CB    1 
ATOM   1127 O OG    . SER   D 2 72  ? 277.647 195.053 244.810 1.00 75.56  ? 84  SER   A OG    1 
ATOM   1128 N N     . ALA   D 2 73  ? 280.285 195.551 245.331 1.00 63.89  ? 85  ALA   A N     1 
ATOM   1129 C CA    . ALA   D 2 73  ? 281.280 195.420 246.389 1.00 63.96  ? 85  ALA   A CA    1 
ATOM   1130 C C     . ALA   D 2 73  ? 281.144 194.054 247.049 1.00 65.67  ? 85  ALA   A C     1 
ATOM   1131 O O     . ALA   D 2 73  ? 280.146 193.775 247.720 1.00 67.57  ? 85  ALA   A O     1 
ATOM   1132 C CB    . ALA   D 2 73  ? 281.119 196.541 247.411 1.00 64.95  ? 85  ALA   A CB    1 
ATOM   1133 N N     . GLY   D 2 74  ? 282.151 193.204 246.866 1.00 63.16  ? 86  GLY   A N     1 
ATOM   1134 C CA    . GLY   D 2 74  ? 282.174 191.903 247.514 1.00 61.23  ? 86  GLY   A CA    1 
ATOM   1135 C C     . GLY   D 2 74  ? 281.058 190.971 247.103 1.00 63.02  ? 86  GLY   A C     1 
ATOM   1136 O O     . GLY   D 2 74  ? 280.602 190.165 247.919 1.00 65.34  ? 86  GLY   A O     1 
ATOM   1137 N N     . LYS   D 2 75  ? 280.612 191.048 245.853 1.00 64.12  ? 87  LYS   A N     1 
ATOM   1138 C CA    . LYS   D 2 75  ? 279.537 190.202 245.361 1.00 59.90  ? 87  LYS   A CA    1 
ATOM   1139 C C     . LYS   D 2 75  ? 279.894 189.679 243.979 1.00 59.15  ? 87  LYS   A C     1 
ATOM   1140 O O     . LYS   D 2 75  ? 280.476 190.402 243.166 1.00 63.52  ? 87  LYS   A O     1 
ATOM   1141 C CB    . LYS   D 2 75  ? 278.209 190.965 245.300 1.00 60.14  ? 87  LYS   A CB    1 
ATOM   1142 C CG    . LYS   D 2 75  ? 277.478 191.058 246.625 1.00 65.01  ? 87  LYS   A CG    1 
ATOM   1143 C CD    . LYS   D 2 75  ? 276.628 192.314 246.687 1.00 67.96  ? 87  LYS   A CD    1 
ATOM   1144 C CE    . LYS   D 2 75  ? 275.903 192.427 248.011 1.00 64.84  ? 87  LYS   A CE    1 
ATOM   1145 N NZ    . LYS   D 2 75  ? 276.742 191.948 249.138 1.00 79.02  ? 87  LYS   A NZ    1 
ATOM   1146 N N     . ASP   D 2 76  ? 279.550 188.426 243.722 1.00 56.89  ? 88  ASP   A N     1 
ATOM   1147 C CA    . ASP   D 2 76  ? 279.737 187.851 242.397 1.00 57.45  ? 88  ASP   A CA    1 
ATOM   1148 C C     . ASP   D 2 76  ? 278.586 188.283 241.497 1.00 57.46  ? 88  ASP   A C     1 
ATOM   1149 O O     . ASP   D 2 76  ? 277.427 188.000 241.818 1.00 59.75  ? 88  ASP   A O     1 
ATOM   1150 C CB    . ASP   D 2 76  ? 279.804 186.333 242.479 1.00 55.36  ? 88  ASP   A CB    1 
ATOM   1151 C CG    . ASP   D 2 76  ? 280.482 185.712 241.277 1.00 56.49  ? 88  ASP   A CG    1 
ATOM   1152 O OD1   . ASP   D 2 76  ? 281.190 186.434 240.550 1.00 61.44  ? 88  ASP   A OD1   1 
ATOM   1153 O OD2   . ASP   D 2 76  ? 280.306 184.497 241.057 1.00 57.03  ? 88  ASP   A OD2   1 
ATOM   1154 N N     . PRO   D 2 77  ? 278.850 188.962 240.377 1.00 54.06  ? 89  PRO   A N     1 
ATOM   1155 C CA    . PRO   D 2 77  ? 277.752 189.463 239.538 1.00 55.05  ? 89  PRO   A CA    1 
ATOM   1156 C C     . PRO   D 2 77  ? 276.980 188.380 238.803 1.00 57.38  ? 89  PRO   A C     1 
ATOM   1157 O O     . PRO   D 2 77  ? 276.000 188.703 238.124 1.00 57.00  ? 89  PRO   A O     1 
ATOM   1158 C CB    . PRO   D 2 77  ? 278.470 190.390 238.549 1.00 56.85  ? 89  PRO   A CB    1 
ATOM   1159 C CG    . PRO   D 2 77  ? 279.849 189.849 238.473 1.00 56.97  ? 89  PRO   A CG    1 
ATOM   1160 C CD    . PRO   D 2 77  ? 280.168 189.353 239.851 1.00 54.88  ? 89  PRO   A CD    1 
ATOM   1161 N N     . LYS   D 2 78  ? 277.383 187.115 238.899 1.00 59.18  ? 90  LYS   A N     1 
ATOM   1162 C CA    . LYS   D 2 78  ? 276.679 186.022 238.244 1.00 55.53  ? 90  LYS   A CA    1 
ATOM   1163 C C     . LYS   D 2 78  ? 275.895 185.163 239.225 1.00 54.51  ? 90  LYS   A C     1 
ATOM   1164 O O     . LYS   D 2 78  ? 275.422 184.086 238.849 1.00 58.59  ? 90  LYS   A O     1 
ATOM   1165 C CB    . LYS   D 2 78  ? 277.661 185.156 237.454 1.00 55.50  ? 90  LYS   A CB    1 
ATOM   1166 C CG    . LYS   D 2 78  ? 278.793 185.939 236.818 1.00 61.28  ? 90  LYS   A CG    1 
ATOM   1167 C CD    . LYS   D 2 78  ? 279.608 185.075 235.875 1.00 64.80  ? 90  LYS   A CD    1 
ATOM   1168 C CE    . LYS   D 2 78  ? 279.097 185.189 234.453 1.00 65.88  ? 90  LYS   A CE    1 
ATOM   1169 N NZ    . LYS   D 2 78  ? 279.000 186.604 234.014 1.00 63.21  ? 90  LYS   A NZ    1 
ATOM   1170 N N     . LYS   D 2 79  ? 275.744 185.609 240.468 1.00 54.63  ? 91  LYS   A N     1 
ATOM   1171 C CA    . LYS   D 2 79  ? 275.048 184.841 241.490 1.00 53.93  ? 91  LYS   A CA    1 
ATOM   1172 C C     . LYS   D 2 79  ? 273.952 185.688 242.116 1.00 53.82  ? 91  LYS   A C     1 
ATOM   1173 O O     . LYS   D 2 79  ? 274.188 186.838 242.497 1.00 57.65  ? 91  LYS   A O     1 
ATOM   1174 C CB    . LYS   D 2 79  ? 276.017 184.351 242.570 1.00 50.51  ? 91  LYS   A CB    1 
ATOM   1175 C CG    . LYS   D 2 79  ? 277.023 183.329 242.078 1.00 53.52  ? 91  LYS   A CG    1 
ATOM   1176 C CD    . LYS   D 2 79  ? 278.062 183.023 243.139 1.00 51.82  ? 91  LYS   A CD    1 
ATOM   1177 C CE    . LYS   D 2 79  ? 277.999 181.574 243.585 1.00 46.57  ? 91  LYS   A CE    1 
ATOM   1178 N NZ    . LYS   D 2 79  ? 278.013 180.642 242.432 1.00 46.21  ? 91  LYS   A NZ    1 
ATOM   1179 N N     . THR   D 2 80  ? 272.759 185.117 242.211 1.00 50.19  ? 92  THR   A N     1 
ATOM   1180 C CA    . THR   D 2 80  ? 271.660 185.689 242.969 1.00 50.73  ? 92  THR   A CA    1 
ATOM   1181 C C     . THR   D 2 80  ? 271.556 184.992 244.318 1.00 53.07  ? 92  THR   A C     1 
ATOM   1182 O O     . THR   D 2 80  ? 272.210 183.981 244.580 1.00 55.90  ? 92  THR   A O     1 
ATOM   1183 C CB    . THR   D 2 80  ? 270.340 185.561 242.205 1.00 53.59  ? 92  THR   A CB    1 
ATOM   1184 O OG1   . THR   D 2 80  ? 270.137 184.195 241.830 1.00 57.67  ? 92  THR   A OG1   1 
ATOM   1185 C CG2   . THR   D 2 80  ? 270.369 186.413 240.962 1.00 57.20  ? 92  THR   A CG2   1 
ATOM   1186 N N     . GLY   D 2 81  ? 270.713 185.542 245.179 1.00 51.44  ? 93  GLY   A N     1 
ATOM   1187 C CA    . GLY   D 2 81  ? 270.571 184.968 246.501 1.00 48.88  ? 93  GLY   A CA    1 
ATOM   1188 C C     . GLY   D 2 81  ? 269.429 185.616 247.244 1.00 51.81  ? 93  GLY   A C     1 
ATOM   1189 O O     . GLY   D 2 81  ? 268.671 186.420 246.696 1.00 55.94  ? 93  GLY   A O     1 
ATOM   1190 N N     . GLY   D 2 82  ? 269.312 185.241 248.510 1.00 49.94  ? 94  GLY   A N     1 
ATOM   1191 C CA    . GLY   D 2 82  ? 268.304 185.790 249.377 1.00 52.16  ? 94  GLY   A CA    1 
ATOM   1192 C C     . GLY   D 2 82  ? 268.205 185.001 250.661 1.00 54.60  ? 94  GLY   A C     1 
ATOM   1193 O O     . GLY   D 2 82  ? 268.839 183.955 250.825 1.00 60.27  ? 94  GLY   A O     1 
ATOM   1194 N N     . PRO   D 2 83  ? 267.407 185.496 251.607 1.00 50.69  ? 95  PRO   A N     1 
ATOM   1195 C CA    . PRO   D 2 83  ? 267.238 184.798 252.889 1.00 51.11  ? 95  PRO   A CA    1 
ATOM   1196 C C     . PRO   D 2 83  ? 266.306 183.607 252.735 1.00 55.38  ? 95  PRO   A C     1 
ATOM   1197 O O     . PRO   D 2 83  ? 265.157 183.752 252.311 1.00 59.09  ? 95  PRO   A O     1 
ATOM   1198 C CB    . PRO   D 2 83  ? 266.632 185.874 253.800 1.00 55.27  ? 95  PRO   A CB    1 
ATOM   1199 C CG    . PRO   D 2 83  ? 266.724 187.168 253.026 1.00 53.80  ? 95  PRO   A CG    1 
ATOM   1200 C CD    . PRO   D 2 83  ? 266.709 186.788 251.593 1.00 49.11  ? 95  PRO   A CD    1 
ATOM   1201 N N     . ILE   D 2 84  ? 266.803 182.424 253.079 1.00 53.16  ? 96  ILE   A N     1 
ATOM   1202 C CA    . ILE   D 2 84  ? 266.004 181.207 253.140 1.00 52.62  ? 96  ILE   A CA    1 
ATOM   1203 C C     . ILE   D 2 84  ? 265.922 180.783 254.598 1.00 51.62  ? 96  ILE   A C     1 
ATOM   1204 O O     . ILE   D 2 84  ? 266.948 180.680 255.279 1.00 50.70  ? 96  ILE   A O     1 
ATOM   1205 C CB    . ILE   D 2 84  ? 266.599 180.093 252.262 1.00 50.48  ? 96  ILE   A CB    1 
ATOM   1206 C CG1   . ILE   D 2 84  ? 266.273 180.354 250.793 1.00 51.72  ? 96  ILE   A CG1   1 
ATOM   1207 C CG2   . ILE   D 2 84  ? 266.066 178.739 252.681 1.00 49.97  ? 96  ILE   A CG2   1 
ATOM   1208 C CD1   . ILE   D 2 84  ? 264.808 180.238 250.472 1.00 52.79  ? 96  ILE   A CD1   1 
ATOM   1209 N N     . TYR   D 2 85  ? 264.707 180.558 255.081 1.00 52.65  ? 97  TYR   A N     1 
ATOM   1210 C CA    . TYR   D 2 85  ? 264.458 180.317 256.494 1.00 51.43  ? 97  TYR   A CA    1 
ATOM   1211 C C     . TYR   D 2 85  ? 264.167 178.843 256.727 1.00 50.65  ? 97  TYR   A C     1 
ATOM   1212 O O     . TYR   D 2 85  ? 263.306 178.260 256.060 1.00 49.77  ? 97  TYR   A O     1 
ATOM   1213 C CB    . TYR   D 2 85  ? 263.301 181.184 256.991 1.00 50.87  ? 97  TYR   A CB    1 
ATOM   1214 C CG    . TYR   D 2 85  ? 263.500 182.651 256.694 1.00 50.11  ? 97  TYR   A CG    1 
ATOM   1215 C CD1   . TYR   D 2 85  ? 264.201 183.466 257.570 1.00 47.93  ? 97  TYR   A CD1   1 
ATOM   1216 C CD2   . TYR   D 2 85  ? 263.001 183.217 255.532 1.00 50.99  ? 97  TYR   A CD2   1 
ATOM   1217 C CE1   . TYR   D 2 85  ? 264.393 184.804 257.299 1.00 48.78  ? 97  TYR   A CE1   1 
ATOM   1218 C CE2   . TYR   D 2 85  ? 263.188 184.554 255.252 1.00 49.65  ? 97  TYR   A CE2   1 
ATOM   1219 C CZ    . TYR   D 2 85  ? 263.885 185.342 256.139 1.00 49.62  ? 97  TYR   A CZ    1 
ATOM   1220 O OH    . TYR   D 2 85  ? 264.071 186.673 255.866 1.00 51.14  ? 97  TYR   A OH    1 
ATOM   1221 N N     . ARG   D 2 86  ? 264.891 178.247 257.668 1.00 53.62  ? 98  ARG   A N     1 
ATOM   1222 C CA    . ARG   D 2 86  ? 264.728 176.846 258.017 1.00 53.37  ? 98  ARG   A CA    1 
ATOM   1223 C C     . ARG   D 2 86  ? 264.377 176.718 259.493 1.00 55.65  ? 98  ARG   A C     1 
ATOM   1224 O O     . ARG   D 2 86  ? 264.836 177.501 260.330 1.00 57.00  ? 98  ARG   A O     1 
ATOM   1225 C CB    . ARG   D 2 86  ? 265.998 176.044 257.711 1.00 51.69  ? 98  ARG   A CB    1 
ATOM   1226 C CG    . ARG   D 2 86  ? 266.434 176.092 256.258 1.00 50.09  ? 98  ARG   A CG    1 
ATOM   1227 C CD    . ARG   D 2 86  ? 267.002 174.758 255.812 1.00 50.70  ? 98  ARG   A CD    1 
ATOM   1228 N NE    . ARG   D 2 86  ? 266.983 174.603 254.362 1.00 47.13  ? 98  ARG   A NE    1 
ATOM   1229 C CZ    . ARG   D 2 86  ? 267.815 175.213 253.530 1.00 50.19  ? 98  ARG   A CZ    1 
ATOM   1230 N NH1   . ARG   D 2 86  ? 268.761 176.025 253.969 1.00 52.06  ? 98  ARG   A NH1   1 
ATOM   1231 N NH2   . ARG   D 2 86  ? 267.696 175.000 252.224 1.00 53.81  ? 98  ARG   A NH2   1 
ATOM   1232 N N     . ARG   D 2 87  ? 263.560 175.719 259.807 1.00 55.16  ? 99  ARG   A N     1 
ATOM   1233 C CA    . ARG   D 2 87  ? 263.148 175.445 261.177 1.00 55.05  ? 99  ARG   A CA    1 
ATOM   1234 C C     . ARG   D 2 87  ? 263.925 174.247 261.706 1.00 55.18  ? 99  ARG   A C     1 
ATOM   1235 O O     . ARG   D 2 87  ? 263.816 173.142 261.166 1.00 57.69  ? 99  ARG   A O     1 
ATOM   1236 C CB    . ARG   D 2 87  ? 261.646 175.181 261.256 1.00 55.43  ? 99  ARG   A CB    1 
ATOM   1237 C CG    . ARG   D 2 87  ? 261.117 175.089 262.674 1.00 54.83  ? 99  ARG   A CG    1 
ATOM   1238 C CD    . ARG   D 2 87  ? 259.624 175.320 262.711 1.00 51.68  ? 99  ARG   A CD    1 
ATOM   1239 N NE    . ARG   D 2 87  ? 258.918 174.330 261.911 1.00 53.02  ? 99  ARG   A NE    1 
ATOM   1240 C CZ    . ARG   D 2 87  ? 257.620 174.084 262.000 1.00 58.89  ? 99  ARG   A CZ    1 
ATOM   1241 N NH1   . ARG   D 2 87  ? 256.847 174.755 262.837 1.00 62.76  ? 99  ARG   A NH1   1 
ATOM   1242 N NH2   . ARG   D 2 87  ? 257.085 173.142 261.230 1.00 61.30  ? 99  ARG   A NH2   1 
ATOM   1243 N N     . VAL   D 2 88  ? 264.700 174.469 262.761 1.00 58.31  ? 100 VAL   A N     1 
ATOM   1244 C CA    . VAL   D 2 88  ? 265.453 173.420 263.432 1.00 61.38  ? 100 VAL   A CA    1 
ATOM   1245 C C     . VAL   D 2 88  ? 265.023 173.412 264.890 1.00 70.42  ? 100 VAL   A C     1 
ATOM   1246 O O     . VAL   D 2 88  ? 265.204 174.412 265.598 1.00 76.23  ? 100 VAL   A O     1 
ATOM   1247 C CB    . VAL   D 2 88  ? 266.969 173.638 263.307 1.00 64.90  ? 100 VAL   A CB    1 
ATOM   1248 C CG1   . VAL   D 2 88  ? 267.718 172.725 264.259 1.00 70.27  ? 100 VAL   A CG1   1 
ATOM   1249 C CG2   . VAL   D 2 88  ? 267.416 173.408 261.876 1.00 65.79  ? 100 VAL   A CG2   1 
ATOM   1250 N N     . ASP   D 2 89  ? 264.445 172.295 265.334 1.00 62.83  ? 101 ASP   A N     1 
ATOM   1251 C CA    . ASP   D 2 89  ? 264.000 172.134 266.719 1.00 65.53  ? 101 ASP   A CA    1 
ATOM   1252 C C     . ASP   D 2 89  ? 263.032 173.241 267.127 1.00 64.66  ? 101 ASP   A C     1 
ATOM   1253 O O     . ASP   D 2 89  ? 263.054 173.724 268.260 1.00 66.63  ? 101 ASP   A O     1 
ATOM   1254 C CB    . ASP   D 2 89  ? 265.190 172.079 267.678 1.00 68.41  ? 101 ASP   A CB    1 
ATOM   1255 C CG    . ASP   D 2 89  ? 265.600 170.665 268.011 1.00 80.21  ? 101 ASP   A CG    1 
ATOM   1256 O OD1   . ASP   D 2 89  ? 264.726 169.775 268.001 1.00 83.76  ? 101 ASP   A OD1   1 
ATOM   1257 O OD2   . ASP   D 2 89  ? 266.797 170.442 268.285 1.00 85.67  ? 101 ASP   A OD2   1 
ATOM   1258 N N     . GLY   D 2 90  ? 262.178 173.651 266.195 1.00 65.00  ? 102 GLY   A N     1 
ATOM   1259 C CA    . GLY   D 2 90  ? 261.208 174.688 266.460 1.00 60.42  ? 102 GLY   A CA    1 
ATOM   1260 C C     . GLY   D 2 90  ? 261.751 176.097 266.422 1.00 63.20  ? 102 GLY   A C     1 
ATOM   1261 O O     . GLY   D 2 90  ? 260.982 177.042 266.634 1.00 69.73  ? 102 GLY   A O     1 
ATOM   1262 N N     . LYS   D 2 91  ? 263.040 176.274 266.155 1.00 59.04  ? 103 LYS   A N     1 
ATOM   1263 C CA    . LYS   D 2 91  ? 263.663 177.588 266.099 1.00 58.65  ? 103 LYS   A CA    1 
ATOM   1264 C C     . LYS   D 2 91  ? 263.952 177.941 264.648 1.00 57.74  ? 103 LYS   A C     1 
ATOM   1265 O O     . LYS   D 2 91  ? 264.486 177.117 263.901 1.00 63.75  ? 103 LYS   A O     1 
ATOM   1266 C CB    . LYS   D 2 91  ? 264.950 177.621 266.922 1.00 60.02  ? 103 LYS   A CB    1 
ATOM   1267 C CG    . LYS   D 2 91  ? 264.725 177.757 268.415 1.00 58.19  ? 103 LYS   A CG    1 
ATOM   1268 C CD    . LYS   D 2 91  ? 264.082 179.085 268.753 1.00 58.05  ? 103 LYS   A CD    1 
ATOM   1269 C CE    . LYS   D 2 91  ? 263.298 179.000 270.046 1.00 64.73  ? 103 LYS   A CE    1 
ATOM   1270 N NZ    . LYS   D 2 91  ? 262.815 177.617 270.300 1.00 74.66  ? 103 LYS   A NZ    1 
ATOM   1271 N N     . TRP   D 2 92  ? 263.586 179.154 264.251 1.00 54.16  ? 104 TRP   A N     1 
ATOM   1272 C CA    . TRP   D 2 92  ? 263.787 179.607 262.884 1.00 54.44  ? 104 TRP   A CA    1 
ATOM   1273 C C     . TRP   D 2 92  ? 265.165 180.233 262.733 1.00 55.62  ? 104 TRP   A C     1 
ATOM   1274 O O     . TRP   D 2 92  ? 265.610 181.000 263.590 1.00 60.32  ? 104 TRP   A O     1 
ATOM   1275 C CB    . TRP   D 2 92  ? 262.711 180.616 262.485 1.00 53.65  ? 104 TRP   A CB    1 
ATOM   1276 C CG    . TRP   D 2 92  ? 261.350 180.019 262.358 1.00 54.41  ? 104 TRP   A CG    1 
ATOM   1277 C CD1   . TRP   D 2 92  ? 260.385 179.970 263.319 1.00 53.91  ? 104 TRP   A CD1   1 
ATOM   1278 C CD2   . TRP   D 2 92  ? 260.799 179.382 261.203 1.00 54.86  ? 104 TRP   A CD2   1 
ATOM   1279 N NE1   . TRP   D 2 92  ? 259.266 179.341 262.833 1.00 53.79  ? 104 TRP   A NE1   1 
ATOM   1280 C CE2   . TRP   D 2 92  ? 259.495 178.972 261.535 1.00 54.84  ? 104 TRP   A CE2   1 
ATOM   1281 C CE3   . TRP   D 2 92  ? 261.281 179.118 259.919 1.00 54.39  ? 104 TRP   A CE3   1 
ATOM   1282 C CZ2   . TRP   D 2 92  ? 258.670 178.312 260.631 1.00 56.04  ? 104 TRP   A CZ2   1 
ATOM   1283 C CZ3   . TRP   D 2 92  ? 260.460 178.464 259.024 1.00 52.74  ? 104 TRP   A CZ3   1 
ATOM   1284 C CH2   . TRP   D 2 92  ? 259.171 178.068 259.383 1.00 53.15  ? 104 TRP   A CH2   1 
ATOM   1285 N N     . ARG   D 2 93  ? 265.840 179.897 261.639 1.00 57.12  ? 105 ARG   A N     1 
ATOM   1286 C CA    . ARG   D 2 93  ? 267.138 180.478 261.342 1.00 58.73  ? 105 ARG   A CA    1 
ATOM   1287 C C     . ARG   D 2 93  ? 267.203 180.849 259.869 1.00 55.41  ? 105 ARG   A C     1 
ATOM   1288 O O     . ARG   D 2 93  ? 266.657 180.154 259.007 1.00 54.87  ? 105 ARG   A O     1 
ATOM   1289 C CB    . ARG   D 2 93  ? 268.283 179.528 261.716 1.00 60.77  ? 105 ARG   A CB    1 
ATOM   1290 C CG    . ARG   D 2 93  ? 268.373 178.274 260.880 1.00 60.72  ? 105 ARG   A CG    1 
ATOM   1291 C CD    . ARG   D 2 93  ? 269.318 177.268 261.513 1.00 66.33  ? 105 ARG   A CD    1 
ATOM   1292 N NE    . ARG   D 2 93  ? 268.893 176.884 262.853 1.00 75.86  ? 105 ARG   A NE    1 
ATOM   1293 C CZ    . ARG   D 2 93  ? 269.473 177.295 263.972 1.00 77.63  ? 105 ARG   A CZ    1 
ATOM   1294 N NH1   . ARG   D 2 93  ? 270.511 178.112 263.951 1.00 75.76  ? 105 ARG   A NH1   1 
ATOM   1295 N NH2   . ARG   D 2 93  ? 268.998 176.875 265.141 1.00 78.05  ? 105 ARG   A NH2   1 
ATOM   1296 N N     . ARG   D 2 94  ? 267.876 181.959 259.595 1.00 53.05  ? 106 ARG   A N     1 
ATOM   1297 C CA    . ARG   D 2 94  ? 267.996 182.494 258.250 1.00 54.93  ? 106 ARG   A CA    1 
ATOM   1298 C C     . ARG   D 2 94  ? 269.341 182.102 257.655 1.00 59.21  ? 106 ARG   A C     1 
ATOM   1299 O O     . ARG   D 2 94  ? 270.347 181.990 258.360 1.00 67.56  ? 106 ARG   A O     1 
ATOM   1300 C CB    . ARG   D 2 94  ? 267.832 184.017 258.256 1.00 55.36  ? 106 ARG   A CB    1 
ATOM   1301 C CG    . ARG   D 2 94  ? 269.097 184.802 257.975 1.00 58.07  ? 106 ARG   A CG    1 
ATOM   1302 C CD    . ARG   D 2 94  ? 268.955 186.248 258.412 1.00 58.60  ? 106 ARG   A CD    1 
ATOM   1303 N NE    . ARG   D 2 94  ? 267.822 186.907 257.776 1.00 54.03  ? 106 ARG   A NE    1 
ATOM   1304 C CZ    . ARG   D 2 94  ? 267.895 187.601 256.649 1.00 55.51  ? 106 ARG   A CZ    1 
ATOM   1305 N NH1   . ARG   D 2 94  ? 269.036 187.740 255.995 1.00 58.93  ? 106 ARG   A NH1   1 
ATOM   1306 N NH2   . ARG   D 2 94  ? 266.796 188.172 256.167 1.00 54.68  ? 106 ARG   A NH2   1 
ATOM   1307 N N     . GLU   D 2 95  ? 269.343 181.872 256.348 1.00 57.46  ? 107 GLU   A N     1 
ATOM   1308 C CA    . GLU   D 2 95  ? 270.529 181.450 255.624 1.00 54.59  ? 107 GLU   A CA    1 
ATOM   1309 C C     . GLU   D 2 95  ? 270.629 182.249 254.336 1.00 54.18  ? 107 GLU   A C     1 
ATOM   1310 O O     . GLU   D 2 95  ? 269.613 182.561 253.711 1.00 54.72  ? 107 GLU   A O     1 
ATOM   1311 C CB    . GLU   D 2 95  ? 270.471 179.952 255.316 1.00 54.27  ? 107 GLU   A CB    1 
ATOM   1312 C CG    . GLU   D 2 95  ? 271.809 179.304 255.063 1.00 58.98  ? 107 GLU   A CG    1 
ATOM   1313 C CD    . GLU   D 2 95  ? 271.691 177.812 254.835 1.00 68.24  ? 107 GLU   A CD    1 
ATOM   1314 O OE1   . GLU   D 2 95  ? 270.780 177.389 254.095 1.00 70.58  ? 107 GLU   A OE1   1 
ATOM   1315 O OE2   . GLU   D 2 95  ? 272.511 177.058 255.398 1.00 74.06  ? 107 GLU   A OE2   1 
ATOM   1316 N N     . LEU   D 2 96  ? 271.849 182.591 253.947 1.00 54.96  ? 108 LEU   A N     1 
ATOM   1317 C CA    . LEU   D 2 96  ? 272.103 183.270 252.684 1.00 54.96  ? 108 LEU   A CA    1 
ATOM   1318 C C     . LEU   D 2 96  ? 272.759 182.260 251.754 1.00 58.06  ? 108 LEU   A C     1 
ATOM   1319 O O     . LEU   D 2 96  ? 273.939 181.935 251.916 1.00 64.09  ? 108 LEU   A O     1 
ATOM   1320 C CB    . LEU   D 2 96  ? 272.988 184.498 252.884 1.00 53.64  ? 108 LEU   A CB    1 
ATOM   1321 C CG    . LEU   D 2 96  ? 272.935 185.550 251.778 1.00 50.28  ? 108 LEU   A CG    1 
ATOM   1322 C CD1   . LEU   D 2 96  ? 271.507 186.012 251.592 1.00 51.22  ? 108 LEU   A CD1   1 
ATOM   1323 C CD2   . LEU   D 2 96  ? 273.833 186.724 252.106 1.00 55.41  ? 108 LEU   A CD2   1 
ATOM   1324 N N     . ILE   D 2 97  ? 271.999 181.762 250.786 1.00 52.14  ? 109 ILE   A N     1 
ATOM   1325 C CA    . ILE   D 2 97  ? 272.490 180.764 249.846 1.00 56.50  ? 109 ILE   A CA    1 
ATOM   1326 C C     . ILE   D 2 97  ? 272.519 181.381 248.453 1.00 55.39  ? 109 ILE   A C     1 
ATOM   1327 O O     . ILE   D 2 97  ? 271.650 182.185 248.097 1.00 56.19  ? 109 ILE   A O     1 
ATOM   1328 C CB    . ILE   D 2 97  ? 271.672 179.451 249.944 1.00 57.96  ? 109 ILE   A CB    1 
ATOM   1329 C CG1   . ILE   D 2 97  ? 270.193 179.577 249.540 1.00 51.16  ? 109 ILE   A CG1   1 
ATOM   1330 C CG2   . ILE   D 2 97  ? 271.778 178.871 251.349 1.00 63.31  ? 109 ILE   A CG2   1 
ATOM   1331 C CD1   . ILE   D 2 97  ? 269.899 179.702 248.071 1.00 55.18  ? 109 ILE   A CD1   1 
ATOM   1332 N N     . LEU   D 2 98  ? 273.558 181.050 247.694 1.00 53.35  ? 110 LEU   A N     1 
ATOM   1333 C CA    . LEU   D 2 98  ? 273.881 181.721 246.442 1.00 52.77  ? 110 LEU   A CA    1 
ATOM   1334 C C     . LEU   D 2 98  ? 273.698 180.756 245.281 1.00 55.69  ? 110 LEU   A C     1 
ATOM   1335 O O     . LEU   D 2 98  ? 274.190 179.625 245.325 1.00 57.52  ? 110 LEU   A O     1 
ATOM   1336 C CB    . LEU   D 2 98  ? 275.317 182.248 246.470 1.00 57.14  ? 110 LEU   A CB    1 
ATOM   1337 C CG    . LEU   D 2 98  ? 275.650 183.173 247.642 1.00 55.65  ? 110 LEU   A CG    1 
ATOM   1338 C CD1   . LEU   D 2 98  ? 277.031 183.787 247.496 1.00 58.90  ? 110 LEU   A CD1   1 
ATOM   1339 C CD2   . LEU   D 2 98  ? 274.596 184.252 247.768 1.00 54.09  ? 110 LEU   A CD2   1 
ATOM   1340 N N     . TYR   D 2 99  ? 272.998 181.207 244.247 1.00 54.82  ? 111 TYR   A N     1 
ATOM   1341 C CA    . TYR   D 2 99  ? 272.693 180.393 243.082 1.00 51.38  ? 111 TYR   A CA    1 
ATOM   1342 C C     . TYR   D 2 99  ? 273.163 181.103 241.822 1.00 52.13  ? 111 TYR   A C     1 
ATOM   1343 O O     . TYR   D 2 99  ? 272.978 182.312 241.678 1.00 53.92  ? 111 TYR   A O     1 
ATOM   1344 C CB    . TYR   D 2 99  ? 271.193 180.119 242.992 1.00 51.69  ? 111 TYR   A CB    1 
ATOM   1345 C CG    . TYR   D 2 99  ? 270.803 178.710 243.347 1.00 52.15  ? 111 TYR   A CG    1 
ATOM   1346 C CD1   . TYR   D 2 99  ? 270.907 177.689 242.418 1.00 57.19  ? 111 TYR   A CD1   1 
ATOM   1347 C CD2   . TYR   D 2 99  ? 270.327 178.401 244.610 1.00 51.41  ? 111 TYR   A CD2   1 
ATOM   1348 C CE1   . TYR   D 2 99  ? 270.549 176.401 242.737 1.00 58.48  ? 111 TYR   A CE1   1 
ATOM   1349 C CE2   . TYR   D 2 99  ? 269.968 177.116 244.937 1.00 55.98  ? 111 TYR   A CE2   1 
ATOM   1350 C CZ    . TYR   D 2 99  ? 270.080 176.120 243.996 1.00 59.77  ? 111 TYR   A CZ    1 
ATOM   1351 O OH    . TYR   D 2 99  ? 269.724 174.832 244.312 1.00 68.93  ? 111 TYR   A OH    1 
ATOM   1352 N N     . ASP   D 2 100 ? 273.764 180.349 240.905 1.00 53.97  ? 112 ASP   A N     1 
ATOM   1353 C CA    . ASP   D 2 100 ? 274.169 180.919 239.627 1.00 52.65  ? 112 ASP   A CA    1 
ATOM   1354 C C     . ASP   D 2 100 ? 272.954 181.433 238.865 1.00 53.22  ? 112 ASP   A C     1 
ATOM   1355 O O     . ASP   D 2 100 ? 271.893 180.804 238.859 1.00 54.54  ? 112 ASP   A O     1 
ATOM   1356 C CB    . ASP   D 2 100 ? 274.906 179.874 238.789 1.00 50.19  ? 112 ASP   A CB    1 
ATOM   1357 C CG    . ASP   D 2 100 ? 276.407 179.964 238.935 1.00 58.00  ? 112 ASP   A CG    1 
ATOM   1358 O OD1   . ASP   D 2 100 ? 276.875 180.443 239.988 1.00 66.52  ? 112 ASP   A OD1   1 
ATOM   1359 O OD2   . ASP   D 2 100 ? 277.121 179.547 238.000 1.00 54.11  ? 112 ASP   A OD2   1 
ATOM   1360 N N     . LYS   D 2 101 ? 273.113 182.590 238.220 1.00 52.44  ? 113 LYS   A N     1 
ATOM   1361 C CA    . LYS   D 2 101 ? 272.014 183.154 237.443 1.00 53.60  ? 113 LYS   A CA    1 
ATOM   1362 C C     . LYS   D 2 101 ? 271.675 182.276 236.245 1.00 53.82  ? 113 LYS   A C     1 
ATOM   1363 O O     . LYS   D 2 101 ? 270.499 182.125 235.894 1.00 54.60  ? 113 LYS   A O     1 
ATOM   1364 C CB    . LYS   D 2 101 ? 272.360 184.573 236.994 1.00 52.70  ? 113 LYS   A CB    1 
ATOM   1365 C CG    . LYS   D 2 101 ? 272.302 185.603 238.108 1.00 48.59  ? 113 LYS   A CG    1 
ATOM   1366 C CD    . LYS   D 2 101 ? 272.899 186.930 237.675 1.00 52.22  ? 113 LYS   A CD    1 
ATOM   1367 C CE    . LYS   D 2 101 ? 273.001 187.911 238.832 1.00 47.41  ? 113 LYS   A CE    1 
ATOM   1368 N NZ    . LYS   D 2 101 ? 271.762 188.704 239.004 1.00 49.07  ? 113 LYS   A NZ    1 
ATOM   1369 N N     . GLU   D 2 102 ? 272.688 181.689 235.603 1.00 54.08  ? 114 GLU   A N     1 
ATOM   1370 C CA    . GLU   D 2 102 ? 272.419 180.811 234.470 1.00 55.82  ? 114 GLU   A CA    1 
ATOM   1371 C C     . GLU   D 2 102 ? 271.679 179.554 234.910 1.00 55.27  ? 114 GLU   A C     1 
ATOM   1372 O O     . GLU   D 2 102 ? 270.816 179.050 234.183 1.00 55.86  ? 114 GLU   A O     1 
ATOM   1373 C CB    . GLU   D 2 102 ? 273.722 180.463 233.747 1.00 56.30  ? 114 GLU   A CB    1 
ATOM   1374 C CG    . GLU   D 2 102 ? 274.587 179.422 234.431 1.00 64.10  ? 114 GLU   A CG    1 
ATOM   1375 C CD    . GLU   D 2 102 ? 275.642 178.855 233.510 1.00 75.86  ? 114 GLU   A CD    1 
ATOM   1376 O OE1   . GLU   D 2 102 ? 275.473 178.961 232.278 1.00 78.78  ? 114 GLU   A OE1   1 
ATOM   1377 O OE2   . GLU   D 2 102 ? 276.641 178.304 234.015 1.00 82.92  ? 114 GLU   A OE2   1 
ATOM   1378 N N     . GLU   D 2 103 ? 271.983 179.047 236.106 1.00 53.75  ? 115 GLU   A N     1 
ATOM   1379 C CA    . GLU   D 2 103 ? 271.241 177.909 236.637 1.00 51.88  ? 115 GLU   A CA    1 
ATOM   1380 C C     . GLU   D 2 103 ? 269.780 178.267 236.875 1.00 52.40  ? 115 GLU   A C     1 
ATOM   1381 O O     . GLU   D 2 103 ? 268.880 177.486 236.546 1.00 55.71  ? 115 GLU   A O     1 
ATOM   1382 C CB    . GLU   D 2 103 ? 271.893 177.422 237.930 1.00 55.82  ? 115 GLU   A CB    1 
ATOM   1383 C CG    . GLU   D 2 103 ? 271.321 176.128 238.460 1.00 58.08  ? 115 GLU   A CG    1 
ATOM   1384 C CD    . GLU   D 2 103 ? 272.000 174.919 237.866 1.00 66.32  ? 115 GLU   A CD    1 
ATOM   1385 O OE1   . GLU   D 2 103 ? 273.009 175.098 237.153 1.00 67.88  ? 115 GLU   A OE1   1 
ATOM   1386 O OE2   . GLU   D 2 103 ? 271.529 173.790 238.110 1.00 71.32  ? 115 GLU   A OE2   1 
ATOM   1387 N N     . ILE   D 2 104 ? 269.527 179.451 237.438 1.00 50.65  ? 116 ILE   A N     1 
ATOM   1388 C CA    . ILE   D 2 104 ? 268.154 179.887 237.679 1.00 51.89  ? 116 ILE   A CA    1 
ATOM   1389 C C     . ILE   D 2 104 ? 267.407 180.044 236.362 1.00 49.65  ? 116 ILE   A C     1 
ATOM   1390 O O     . ILE   D 2 104 ? 266.242 179.647 236.241 1.00 49.39  ? 116 ILE   A O     1 
ATOM   1391 C CB    . ILE   D 2 104 ? 268.143 181.192 238.496 1.00 50.81  ? 116 ILE   A CB    1 
ATOM   1392 C CG1   . ILE   D 2 104 ? 268.790 180.972 239.862 1.00 49.72  ? 116 ILE   A CG1   1 
ATOM   1393 C CG2   . ILE   D 2 104 ? 266.727 181.704 238.668 1.00 50.31  ? 116 ILE   A CG2   1 
ATOM   1394 C CD1   . ILE   D 2 104 ? 268.000 180.065 240.765 1.00 54.45  ? 116 ILE   A CD1   1 
ATOM   1395 N N     . ARG   D 2 105 ? 268.060 180.634 235.358 1.00 49.97  ? 117 ARG   A N     1 
ATOM   1396 C CA    . ARG   D 2 105 ? 267.423 180.793 234.056 1.00 49.17  ? 117 ARG   A CA    1 
ATOM   1397 C C     . ARG   D 2 105 ? 267.115 179.442 233.423 1.00 50.45  ? 117 ARG   A C     1 
ATOM   1398 O O     . ARG   D 2 105 ? 266.037 179.249 232.851 1.00 52.11  ? 117 ARG   A O     1 
ATOM   1399 C CB    . ARG   D 2 105 ? 268.309 181.629 233.134 1.00 48.53  ? 117 ARG   A CB    1 
ATOM   1400 C CG    . ARG   D 2 105 ? 268.335 183.106 233.475 1.00 47.88  ? 117 ARG   A CG    1 
ATOM   1401 C CD    . ARG   D 2 105 ? 269.015 183.914 232.387 1.00 48.68  ? 117 ARG   A CD    1 
ATOM   1402 N NE    . ARG   D 2 105 ? 270.451 183.670 232.343 1.00 49.36  ? 117 ARG   A NE    1 
ATOM   1403 C CZ    . ARG   D 2 105 ? 271.351 184.386 233.000 1.00 46.28  ? 117 ARG   A CZ    1 
ATOM   1404 N NH1   . ARG   D 2 105 ? 271.000 185.413 233.754 1.00 50.11  ? 117 ARG   A NH1   1 
ATOM   1405 N NH2   . ARG   D 2 105 ? 272.636 184.064 232.897 1.00 46.05  ? 117 ARG   A NH2   1 
ATOM   1406 N N     . ARG   D 2 106 ? 268.053 178.495 233.513 1.00 50.63  ? 118 ARG   A N     1 
ATOM   1407 C CA    . ARG   D 2 106 ? 267.814 177.163 232.969 1.00 50.06  ? 118 ARG   A CA    1 
ATOM   1408 C C     . ARG   D 2 106 ? 266.636 176.491 233.659 1.00 48.19  ? 118 ARG   A C     1 
ATOM   1409 O O     . ARG   D 2 106 ? 265.788 175.880 233.000 1.00 48.84  ? 118 ARG   A O     1 
ATOM   1410 C CB    . ARG   D 2 106 ? 269.071 176.306 233.107 1.00 47.60  ? 118 ARG   A CB    1 
ATOM   1411 C CG    . ARG   D 2 106 ? 268.846 174.828 232.846 1.00 44.42  ? 118 ARG   A CG    1 
ATOM   1412 C CD    . ARG   D 2 106 ? 270.001 173.992 233.362 1.00 45.46  ? 118 ARG   A CD    1 
ATOM   1413 N NE    . ARG   D 2 106 ? 269.830 173.605 234.757 1.00 49.51  ? 118 ARG   A NE    1 
ATOM   1414 C CZ    . ARG   D 2 106 ? 269.055 172.611 235.170 1.00 51.77  ? 118 ARG   A CZ    1 
ATOM   1415 N NH1   . ARG   D 2 106 ? 268.342 171.892 234.321 1.00 57.28  ? 118 ARG   A NH1   1 
ATOM   1416 N NH2   . ARG   D 2 106 ? 268.996 172.331 236.468 1.00 45.46  ? 118 ARG   A NH2   1 
ATOM   1417 N N     . ILE   D 2 107 ? 266.564 176.603 234.986 1.00 49.47  ? 119 ILE   A N     1 
ATOM   1418 C CA    . ILE   D 2 107 ? 265.472 175.983 235.729 1.00 48.26  ? 119 ILE   A CA    1 
ATOM   1419 C C     . ILE   D 2 107 ? 264.139 176.621 235.355 1.00 50.84  ? 119 ILE   A C     1 
ATOM   1420 O O     . ILE   D 2 107 ? 263.132 175.927 235.165 1.00 52.82  ? 119 ILE   A O     1 
ATOM   1421 C CB    . ILE   D 2 107 ? 265.748 176.064 237.241 1.00 47.18  ? 119 ILE   A CB    1 
ATOM   1422 C CG1   . ILE   D 2 107 ? 266.934 175.169 237.602 1.00 46.19  ? 119 ILE   A CG1   1 
ATOM   1423 C CG2   . ILE   D 2 107 ? 264.520 175.666 238.033 1.00 53.66  ? 119 ILE   A CG2   1 
ATOM   1424 C CD1   . ILE   D 2 107 ? 267.368 175.275 239.035 1.00 52.62  ? 119 ILE   A CD1   1 
ATOM   1425 N N     . TRP   D 2 108 ? 264.111 177.949 235.234 1.00 49.80  ? 120 TRP   A N     1 
ATOM   1426 C CA    . TRP   D 2 108 ? 262.876 178.628 234.859 1.00 49.06  ? 120 TRP   A CA    1 
ATOM   1427 C C     . TRP   D 2 108 ? 262.431 178.237 233.456 1.00 52.54  ? 120 TRP   A C     1 
ATOM   1428 O O     . TRP   D 2 108 ? 261.241 178.001 233.219 1.00 55.93  ? 120 TRP   A O     1 
ATOM   1429 C CB    . TRP   D 2 108 ? 263.056 180.140 234.961 1.00 48.63  ? 120 TRP   A CB    1 
ATOM   1430 C CG    . TRP   D 2 108 ? 261.912 180.906 234.395 1.00 50.17  ? 120 TRP   A CG    1 
ATOM   1431 C CD1   . TRP   D 2 108 ? 261.863 181.529 233.187 1.00 53.22  ? 120 TRP   A CD1   1 
ATOM   1432 C CD2   . TRP   D 2 108 ? 260.638 181.116 235.008 1.00 51.11  ? 120 TRP   A CD2   1 
ATOM   1433 N NE1   . TRP   D 2 108 ? 260.641 182.126 233.012 1.00 54.28  ? 120 TRP   A NE1   1 
ATOM   1434 C CE2   . TRP   D 2 108 ? 259.871 181.889 234.120 1.00 51.43  ? 120 TRP   A CE2   1 
ATOM   1435 C CE3   . TRP   D 2 108 ? 260.075 180.733 236.226 1.00 53.80  ? 120 TRP   A CE3   1 
ATOM   1436 C CZ2   . TRP   D 2 108 ? 258.568 182.279 234.407 1.00 50.45  ? 120 TRP   A CZ2   1 
ATOM   1437 C CZ3   . TRP   D 2 108 ? 258.784 181.122 236.508 1.00 51.23  ? 120 TRP   A CZ3   1 
ATOM   1438 C CH2   . TRP   D 2 108 ? 258.045 181.886 235.603 1.00 47.88  ? 120 TRP   A CH2   1 
ATOM   1439 N N     . ARG   D 2 109 ? 263.369 178.168 232.510 1.00 50.81  ? 121 ARG   A N     1 
ATOM   1440 C CA    . ARG   D 2 109 ? 263.014 177.788 231.147 1.00 51.92  ? 121 ARG   A CA    1 
ATOM   1441 C C     . ARG   D 2 109 ? 262.522 176.350 231.085 1.00 53.09  ? 121 ARG   A C     1 
ATOM   1442 O O     . ARG   D 2 109 ? 261.557 176.049 230.375 1.00 57.72  ? 121 ARG   A O     1 
ATOM   1443 C CB    . ARG   D 2 109 ? 264.207 177.988 230.217 1.00 53.12  ? 121 ARG   A CB    1 
ATOM   1444 C CG    . ARG   D 2 109 ? 264.271 179.364 229.594 1.00 52.57  ? 121 ARG   A CG    1 
ATOM   1445 C CD    . ARG   D 2 109 ? 265.568 179.556 228.843 1.00 49.71  ? 121 ARG   A CD    1 
ATOM   1446 N NE    . ARG   D 2 109 ? 265.980 180.952 228.823 1.00 53.87  ? 121 ARG   A NE    1 
ATOM   1447 C CZ    . ARG   D 2 109 ? 267.222 181.364 229.027 1.00 55.33  ? 121 ARG   A CZ    1 
ATOM   1448 N NH1   . ARG   D 2 109 ? 268.201 180.508 229.270 1.00 50.55  ? 121 ARG   A NH1   1 
ATOM   1449 N NH2   . ARG   D 2 109 ? 267.488 182.665 228.991 1.00 53.61  ? 121 ARG   A NH2   1 
ATOM   1450 N N     . GLN   D 2 110 ? 263.172 175.447 231.822 1.00 51.03  ? 122 GLN   A N     1 
ATOM   1451 C CA    . GLN   D 2 110 ? 262.704 174.070 231.878 1.00 52.11  ? 122 GLN   A CA    1 
ATOM   1452 C C     . GLN   D 2 110 ? 261.322 173.983 232.509 1.00 53.53  ? 122 GLN   A C     1 
ATOM   1453 O O     . GLN   D 2 110 ? 260.525 173.112 232.144 1.00 54.26  ? 122 GLN   A O     1 
ATOM   1454 C CB    . GLN   D 2 110 ? 263.710 173.215 232.647 1.00 48.91  ? 122 GLN   A CB    1 
ATOM   1455 C CG    . GLN   D 2 110 ? 263.348 171.753 232.749 1.00 51.46  ? 122 GLN   A CG    1 
ATOM   1456 C CD    . GLN   D 2 110 ? 264.384 170.967 233.513 1.00 58.12  ? 122 GLN   A CD    1 
ATOM   1457 O OE1   . GLN   D 2 110 ? 265.562 170.976 233.166 1.00 54.67  ? 122 GLN   A OE1   1 
ATOM   1458 N NE2   . GLN   D 2 110 ? 263.953 170.285 234.564 1.00 63.45  ? 122 GLN   A NE2   1 
ATOM   1459 N N     . ALA   D 2 111 ? 261.019 174.882 233.446 1.00 53.18  ? 123 ALA   A N     1 
ATOM   1460 C CA    . ALA   D 2 111 ? 259.684 174.922 234.031 1.00 53.27  ? 123 ALA   A CA    1 
ATOM   1461 C C     . ALA   D 2 111 ? 258.633 175.312 232.999 1.00 55.94  ? 123 ALA   A C     1 
ATOM   1462 O O     . ALA   D 2 111 ? 257.525 174.768 233.000 1.00 60.32  ? 123 ALA   A O     1 
ATOM   1463 C CB    . ALA   D 2 111 ? 259.661 175.887 235.212 1.00 54.09  ? 123 ALA   A CB    1 
ATOM   1464 N N     . ASN   D 2 112 ? 258.952 176.253 232.112 1.00 53.18  ? 124 ASN   A N     1 
ATOM   1465 C CA    . ASN   D 2 112 ? 258.015 176.695 231.087 1.00 54.83  ? 124 ASN   A CA    1 
ATOM   1466 C C     . ASN   D 2 112 ? 258.181 175.951 229.770 1.00 57.42  ? 124 ASN   A C     1 
ATOM   1467 O O     . ASN   D 2 112 ? 257.795 176.481 228.722 1.00 57.04  ? 124 ASN   A O     1 
ATOM   1468 C CB    . ASN   D 2 112 ? 258.158 178.194 230.847 1.00 56.02  ? 124 ASN   A CB    1 
ATOM   1469 C CG    . ASN   D 2 112 ? 257.862 179.007 232.074 1.00 56.87  ? 124 ASN   A CG    1 
ATOM   1470 O OD1   . ASN   D 2 112 ? 257.112 178.587 232.950 1.00 57.81  ? 124 ASN   A OD1   1 
ATOM   1471 N ND2   . ASN   D 2 112 ? 258.455 180.183 232.149 1.00 61.40  ? 124 ASN   A ND2   1 
ATOM   1472 N N     . ASN   D 2 113 ? 258.749 174.745 229.802 1.00 59.84  ? 125 ASN   A N     1 
ATOM   1473 C CA    . ASN   D 2 113 ? 258.970 173.926 228.611 1.00 59.75  ? 125 ASN   A CA    1 
ATOM   1474 C C     . ASN   D 2 113 ? 259.896 174.631 227.617 1.00 59.50  ? 125 ASN   A C     1 
ATOM   1475 O O     . ASN   D 2 113 ? 259.536 174.912 226.473 1.00 62.97  ? 125 ASN   A O     1 
ATOM   1476 C CB    . ASN   D 2 113 ? 257.639 173.544 227.957 1.00 57.84  ? 125 ASN   A CB    1 
ATOM   1477 C CG    . ASN   D 2 113 ? 256.842 172.579 228.797 1.00 67.37  ? 125 ASN   A CG    1 
ATOM   1478 O OD1   . ASN   D 2 113 ? 257.331 172.067 229.803 1.00 66.33  ? 125 ASN   A OD1   1 
ATOM   1479 N ND2   . ASN   D 2 113 ? 255.603 172.327 228.396 1.00 79.78  ? 125 ASN   A ND2   1 
ATOM   1480 N N     . GLY   D 2 114 ? 261.110 174.912 228.083 1.00 53.87  ? 126 GLY   A N     1 
ATOM   1481 C CA    . GLY   D 2 114 ? 262.140 175.465 227.228 1.00 54.85  ? 126 GLY   A CA    1 
ATOM   1482 C C     . GLY   D 2 114 ? 261.890 176.869 226.736 1.00 60.13  ? 126 GLY   A C     1 
ATOM   1483 O O     . GLY   D 2 114 ? 262.616 177.338 225.856 1.00 64.94  ? 126 GLY   A O     1 
ATOM   1484 N N     . ASP   D 2 115 ? 260.892 177.557 227.275 1.00 62.30  ? 127 ASP   A N     1 
ATOM   1485 C CA    . ASP   D 2 115 ? 260.545 178.904 226.854 1.00 60.82  ? 127 ASP   A CA    1 
ATOM   1486 C C     . ASP   D 2 115 ? 260.789 179.874 227.999 1.00 64.46  ? 127 ASP   A C     1 
ATOM   1487 O O     . ASP   D 2 115 ? 260.491 179.570 229.157 1.00 68.60  ? 127 ASP   A O     1 
ATOM   1488 C CB    . ASP   D 2 115 ? 259.084 178.977 226.404 1.00 59.71  ? 127 ASP   A CB    1 
ATOM   1489 C CG    . ASP   D 2 115 ? 258.676 180.369 225.978 1.00 71.77  ? 127 ASP   A CG    1 
ATOM   1490 O OD1   . ASP   D 2 115 ? 259.563 181.170 225.620 1.00 74.03  ? 127 ASP   A OD1   1 
ATOM   1491 O OD2   . ASP   D 2 115 ? 257.463 180.663 226.001 1.00 79.79  ? 127 ASP   A OD2   1 
ATOM   1492 N N     . ASP   D 2 116 ? 261.343 181.039 227.670 1.00 62.27  ? 128 ASP   A N     1 
ATOM   1493 C CA    . ASP   D 2 116 ? 261.562 182.096 228.655 1.00 61.33  ? 128 ASP   A CA    1 
ATOM   1494 C C     . ASP   D 2 116 ? 260.293 182.937 228.742 1.00 61.06  ? 128 ASP   A C     1 
ATOM   1495 O O     . ASP   D 2 116 ? 260.209 184.062 228.244 1.00 69.83  ? 128 ASP   A O     1 
ATOM   1496 C CB    . ASP   D 2 116 ? 262.788 182.923 228.290 1.00 62.78  ? 128 ASP   A CB    1 
ATOM   1497 C CG    . ASP   D 2 116 ? 262.755 183.413 226.860 1.00 70.97  ? 128 ASP   A CG    1 
ATOM   1498 O OD1   . ASP   D 2 116 ? 261.824 183.033 226.122 1.00 72.44  ? 128 ASP   A OD1   1 
ATOM   1499 O OD2   . ASP   D 2 116 ? 263.662 184.177 226.473 1.00 78.26  ? 128 ASP   A OD2   1 
ATOM   1500 N N     . ALA   D 2 117 ? 259.286 182.369 229.397 1.00 55.43  ? 129 ALA   A N     1 
ATOM   1501 C CA    . ALA   D 2 117 ? 257.971 182.996 229.481 1.00 57.38  ? 129 ALA   A CA    1 
ATOM   1502 C C     . ALA   D 2 117 ? 258.062 184.217 230.382 1.00 56.04  ? 129 ALA   A C     1 
ATOM   1503 O O     . ALA   D 2 117 ? 258.062 184.105 231.609 1.00 56.81  ? 129 ALA   A O     1 
ATOM   1504 C CB    . ALA   D 2 117 ? 256.937 182.004 229.999 1.00 56.48  ? 129 ALA   A CB    1 
ATOM   1505 N N     . THR   D 2 118 ? 258.144 185.397 229.769 1.00 51.23  ? 130 THR   A N     1 
ATOM   1506 C CA    . THR   D 2 118 ? 258.208 186.634 230.530 1.00 52.59  ? 130 THR   A CA    1 
ATOM   1507 C C     . THR   D 2 118 ? 256.876 187.000 231.168 1.00 53.16  ? 130 THR   A C     1 
ATOM   1508 O O     . THR   D 2 118 ? 256.847 187.875 232.038 1.00 55.58  ? 130 THR   A O     1 
ATOM   1509 C CB    . THR   D 2 118 ? 258.688 187.773 229.630 1.00 54.43  ? 130 THR   A CB    1 
ATOM   1510 O OG1   . THR   D 2 118 ? 257.726 188.000 228.594 1.00 61.12  ? 130 THR   A OG1   1 
ATOM   1511 C CG2   . THR   D 2 118 ? 260.019 187.416 229.000 1.00 52.56  ? 130 THR   A CG2   1 
ATOM   1512 N N     . ALA   D 2 119 ? 255.782 186.352 230.760 1.00 48.39  ? 131 ALA   A N     1 
ATOM   1513 C CA    . ALA   D 2 119 ? 254.480 186.642 231.352 1.00 47.97  ? 131 ALA   A CA    1 
ATOM   1514 C C     . ALA   D 2 119 ? 254.439 186.255 232.825 1.00 49.18  ? 131 ALA   A C     1 
ATOM   1515 O O     . ALA   D 2 119 ? 253.901 186.998 233.651 1.00 51.06  ? 131 ALA   A O     1 
ATOM   1516 C CB    . ALA   D 2 119 ? 253.380 185.924 230.574 1.00 49.33  ? 131 ALA   A CB    1 
ATOM   1517 N N     . GLY   D 2 120 ? 255.004 185.099 233.176 1.00 46.72  ? 132 GLY   A N     1 
ATOM   1518 C CA    . GLY   D 2 120 ? 255.066 184.716 234.578 1.00 47.09  ? 132 GLY   A CA    1 
ATOM   1519 C C     . GLY   D 2 120 ? 255.953 185.636 235.396 1.00 48.22  ? 132 GLY   A C     1 
ATOM   1520 O O     . GLY   D 2 120 ? 255.652 185.939 236.556 1.00 50.69  ? 132 GLY   A O     1 
ATOM   1521 N N     . LEU   D 2 121 ? 257.062 186.087 234.807 1.00 46.86  ? 133 LEU   A N     1 
ATOM   1522 C CA    . LEU   D 2 121 ? 257.910 187.061 235.483 1.00 50.33  ? 133 LEU   A CA    1 
ATOM   1523 C C     . LEU   D 2 121 ? 257.152 188.355 235.742 1.00 49.09  ? 133 LEU   A C     1 
ATOM   1524 O O     . LEU   D 2 121 ? 257.244 188.929 236.832 1.00 48.50  ? 133 LEU   A O     1 
ATOM   1525 C CB    . LEU   D 2 121 ? 259.163 187.333 234.654 1.00 52.46  ? 133 LEU   A CB    1 
ATOM   1526 C CG    . LEU   D 2 121 ? 259.897 186.111 234.108 1.00 47.11  ? 133 LEU   A CG    1 
ATOM   1527 C CD1   . LEU   D 2 121 ? 261.103 186.541 233.300 1.00 50.81  ? 133 LEU   A CD1   1 
ATOM   1528 C CD2   . LEU   D 2 121 ? 260.309 185.208 235.243 1.00 44.82  ? 133 LEU   A CD2   1 
ATOM   1529 N N     . THR   D 2 122 ? 256.389 188.823 234.752 1.00 49.99  ? 134 THR   A N     1 
ATOM   1530 C CA    . THR   D 2 122 ? 255.572 190.016 234.945 1.00 48.97  ? 134 THR   A CA    1 
ATOM   1531 C C     . THR   D 2 122 ? 254.498 189.788 236.000 1.00 47.31  ? 134 THR   A C     1 
ATOM   1532 O O     . THR   D 2 122 ? 254.160 190.707 236.752 1.00 49.78  ? 134 THR   A O     1 
ATOM   1533 C CB    . THR   D 2 122 ? 254.939 190.437 233.618 1.00 50.91  ? 134 THR   A CB    1 
ATOM   1534 O OG1   . THR   D 2 122 ? 255.943 190.461 232.597 1.00 49.13  ? 134 THR   A OG1   1 
ATOM   1535 C CG2   . THR   D 2 122 ? 254.321 191.819 233.734 1.00 54.36  ? 134 THR   A CG2   1 
ATOM   1536 N N     . HIS   D 2 123 ? 253.961 188.569 236.075 1.00 46.30  ? 135 HIS   A N     1 
ATOM   1537 C CA    . HIS   D 2 123 ? 252.985 188.234 237.107 1.00 46.55  ? 135 HIS   A CA    1 
ATOM   1538 C C     . HIS   D 2 123 ? 253.593 188.346 238.503 1.00 46.78  ? 135 HIS   A C     1 
ATOM   1539 O O     . HIS   D 2 123 ? 253.001 188.948 239.408 1.00 46.26  ? 135 HIS   A O     1 
ATOM   1540 C CB    . HIS   D 2 123 ? 252.450 186.825 236.853 1.00 45.57  ? 135 HIS   A CB    1 
ATOM   1541 C CG    . HIS   D 2 123 ? 251.286 186.448 237.712 1.00 50.03  ? 135 HIS   A CG    1 
ATOM   1542 N ND1   . HIS   D 2 123 ? 249.995 186.834 237.425 1.00 54.90  ? 135 HIS   A ND1   1 
ATOM   1543 C CD2   . HIS   D 2 123 ? 251.213 185.696 238.835 1.00 50.50  ? 135 HIS   A CD2   1 
ATOM   1544 C CE1   . HIS   D 2 123 ? 249.179 186.346 238.342 1.00 53.86  ? 135 HIS   A CE1   1 
ATOM   1545 N NE2   . HIS   D 2 123 ? 249.893 185.652 239.209 1.00 52.07  ? 135 HIS   A NE2   1 
ATOM   1546 N N     . MET   D 2 124 ? 254.785 187.776 238.692 1.00 46.10  ? 136 MET   A N     1 
ATOM   1547 C CA    . MET   D 2 124 ? 255.462 187.890 239.983 1.00 45.67  ? 136 MET   A CA    1 
ATOM   1548 C C     . MET   D 2 124 ? 255.817 189.339 240.287 1.00 46.92  ? 136 MET   A C     1 
ATOM   1549 O O     . MET   D 2 124 ? 255.759 189.779 241.443 1.00 48.92  ? 136 MET   A O     1 
ATOM   1550 C CB    . MET   D 2 124 ? 256.719 187.023 240.007 1.00 47.38  ? 136 MET   A CB    1 
ATOM   1551 C CG    . MET   D 2 124 ? 256.458 185.537 240.021 1.00 49.55  ? 136 MET   A CG    1 
ATOM   1552 S SD    . MET   D 2 124 ? 257.995 184.604 240.032 1.00 63.77  ? 136 MET   A SD    1 
ATOM   1553 C CE    . MET   D 2 124 ? 258.002 183.977 238.364 1.00 53.68  ? 136 MET   A CE    1 
ATOM   1554 N N     . MET   D 2 125 ? 256.193 190.090 239.255 1.00 47.42  ? 137 MET   A N     1 
ATOM   1555 C CA    . MET   D 2 125 ? 256.495 191.506 239.413 1.00 46.42  ? 137 MET   A CA    1 
ATOM   1556 C C     . MET   D 2 125 ? 255.274 192.269 239.909 1.00 46.10  ? 137 MET   A C     1 
ATOM   1557 O O     . MET   D 2 125 ? 255.378 193.110 240.809 1.00 45.01  ? 137 MET   A O     1 
ATOM   1558 C CB    . MET   D 2 125 ? 256.985 192.048 238.072 1.00 45.94  ? 137 MET   A CB    1 
ATOM   1559 C CG    . MET   D 2 125 ? 258.484 191.937 237.879 1.00 51.62  ? 137 MET   A CG    1 
ATOM   1560 S SD    . MET   D 2 125 ? 258.967 191.902 236.143 1.00 56.34  ? 137 MET   A SD    1 
ATOM   1561 C CE    . MET   D 2 125 ? 258.972 193.634 235.742 1.00 55.98  ? 137 MET   A CE    1 
ATOM   1562 N N     . ILE   D 2 126 ? 254.103 191.969 239.345 1.00 48.80  ? 138 ILE   A N     1 
ATOM   1563 C CA    . ILE   D 2 126 ? 252.870 192.623 239.771 1.00 47.26  ? 138 ILE   A CA    1 
ATOM   1564 C C     . ILE   D 2 126 ? 252.507 192.210 241.192 1.00 46.05  ? 138 ILE   A C     1 
ATOM   1565 O O     . ILE   D 2 126 ? 252.000 193.020 241.973 1.00 48.70  ? 138 ILE   A O     1 
ATOM   1566 C CB    . ILE   D 2 126 ? 251.733 192.317 238.778 1.00 44.88  ? 138 ILE   A CB    1 
ATOM   1567 C CG1   . ILE   D 2 126 ? 252.025 192.954 237.422 1.00 47.02  ? 138 ILE   A CG1   1 
ATOM   1568 C CG2   . ILE   D 2 126 ? 250.413 192.849 239.297 1.00 51.82  ? 138 ILE   A CG2   1 
ATOM   1569 C CD1   . ILE   D 2 126 ? 251.058 192.546 236.344 1.00 47.24  ? 138 ILE   A CD1   1 
ATOM   1570 N N     . TRP   D 2 127 ? 252.752 190.949 241.550 1.00 46.55  ? 139 TRP   A N     1 
ATOM   1571 C CA    . TRP   D 2 127 ? 252.494 190.514 242.922 1.00 45.59  ? 139 TRP   A CA    1 
ATOM   1572 C C     . TRP   D 2 127 ? 253.352 191.295 243.913 1.00 45.59  ? 139 TRP   A C     1 
ATOM   1573 O O     . TRP   D 2 127 ? 252.859 191.783 244.940 1.00 45.81  ? 139 TRP   A O     1 
ATOM   1574 C CB    . TRP   D 2 127 ? 252.742 189.010 243.047 1.00 45.40  ? 139 TRP   A CB    1 
ATOM   1575 C CG    . TRP   D 2 127 ? 253.314 188.565 244.363 1.00 46.05  ? 139 TRP   A CG    1 
ATOM   1576 C CD1   . TRP   D 2 127 ? 254.535 187.998 244.571 1.00 45.68  ? 139 TRP   A CD1   1 
ATOM   1577 C CD2   . TRP   D 2 127 ? 252.678 188.626 245.646 1.00 46.98  ? 139 TRP   A CD2   1 
ATOM   1578 N NE1   . TRP   D 2 127 ? 254.707 187.713 245.902 1.00 45.50  ? 139 TRP   A NE1   1 
ATOM   1579 C CE2   . TRP   D 2 127 ? 253.580 188.088 246.583 1.00 46.22  ? 139 TRP   A CE2   1 
ATOM   1580 C CE3   . TRP   D 2 127 ? 251.438 189.088 246.093 1.00 46.76  ? 139 TRP   A CE3   1 
ATOM   1581 C CZ2   . TRP   D 2 127 ? 253.281 188.001 247.939 1.00 45.41  ? 139 TRP   A CZ2   1 
ATOM   1582 C CZ3   . TRP   D 2 127 ? 251.144 188.999 247.439 1.00 45.18  ? 139 TRP   A CZ3   1 
ATOM   1583 C CH2   . TRP   D 2 127 ? 252.060 188.461 248.345 1.00 44.76  ? 139 TRP   A CH2   1 
ATOM   1584 N N     . HIS   D 2 128 ? 254.641 191.443 243.605 1.00 47.28  ? 140 HIS   A N     1 
ATOM   1585 C CA    . HIS   D 2 128 ? 255.517 192.224 244.472 1.00 46.19  ? 140 HIS   A CA    1 
ATOM   1586 C C     . HIS   D 2 128 ? 255.078 193.681 244.530 1.00 46.25  ? 140 HIS   A C     1 
ATOM   1587 O O     . HIS   D 2 128 ? 255.104 194.303 245.599 1.00 47.64  ? 140 HIS   A O     1 
ATOM   1588 C CB    . HIS   D 2 128 ? 256.964 192.117 243.995 1.00 45.07  ? 140 HIS   A CB    1 
ATOM   1589 C CG    . HIS   D 2 128 ? 257.581 190.779 244.246 1.00 46.50  ? 140 HIS   A CG    1 
ATOM   1590 N ND1   . HIS   D 2 128 ? 258.701 190.337 243.578 1.00 52.47  ? 140 HIS   A ND1   1 
ATOM   1591 C CD2   . HIS   D 2 128 ? 257.230 189.783 245.093 1.00 48.14  ? 140 HIS   A CD2   1 
ATOM   1592 C CE1   . HIS   D 2 128 ? 259.015 189.127 244.003 1.00 50.57  ? 140 HIS   A CE1   1 
ATOM   1593 N NE2   . HIS   D 2 128 ? 258.139 188.768 244.923 1.00 49.91  ? 140 HIS   A NE2   1 
ATOM   1594 N N     . SER   D 2 129 ? 254.679 194.244 243.388 1.00 46.18  ? 141 SER   A N     1 
ATOM   1595 C CA    . SER   D 2 129 ? 254.229 195.631 243.360 1.00 47.52  ? 141 SER   A CA    1 
ATOM   1596 C C     . SER   D 2 129 ? 252.984 195.827 244.214 1.00 48.25  ? 141 SER   A C     1 
ATOM   1597 O O     . SER   D 2 129 ? 252.878 196.813 244.948 1.00 48.60  ? 141 SER   A O     1 
ATOM   1598 C CB    . SER   D 2 129 ? 253.963 196.065 241.922 1.00 47.98  ? 141 SER   A CB    1 
ATOM   1599 O OG    . SER   D 2 129 ? 253.014 197.113 241.883 1.00 54.29  ? 141 SER   A OG    1 
ATOM   1600 N N     . ASN   D 2 130 ? 252.032 194.896 244.130 1.00 48.24  ? 142 ASN   A N     1 
ATOM   1601 C CA    . ASN   D 2 130 ? 250.829 194.975 244.952 1.00 48.02  ? 142 ASN   A CA    1 
ATOM   1602 C C     . ASN   D 2 130 ? 251.163 194.869 246.435 1.00 46.92  ? 142 ASN   A C     1 
ATOM   1603 O O     . ASN   D 2 130 ? 250.591 195.590 247.262 1.00 45.91  ? 142 ASN   A O     1 
ATOM   1604 C CB    . ASN   D 2 130 ? 249.849 193.874 244.550 1.00 48.29  ? 142 ASN   A CB    1 
ATOM   1605 C CG    . ASN   D 2 130 ? 249.213 194.120 243.199 1.00 51.28  ? 142 ASN   A CG    1 
ATOM   1606 O OD1   . ASN   D 2 130 ? 249.310 195.212 242.644 1.00 53.15  ? 142 ASN   A OD1   1 
ATOM   1607 N ND2   . ASN   D 2 130 ? 248.556 193.101 242.664 1.00 48.01  ? 142 ASN   A ND2   1 
ATOM   1608 N N     . LEU   D 2 131 ? 252.082 193.967 246.791 1.00 45.64  ? 143 LEU   A N     1 
ATOM   1609 C CA    . LEU   D 2 131 ? 252.494 193.849 248.187 1.00 46.89  ? 143 LEU   A CA    1 
ATOM   1610 C C     . LEU   D 2 131 ? 253.128 195.141 248.688 1.00 46.97  ? 143 LEU   A C     1 
ATOM   1611 O O     . LEU   D 2 131 ? 252.824 195.608 249.793 1.00 47.24  ? 143 LEU   A O     1 
ATOM   1612 C CB    . LEU   D 2 131 ? 253.461 192.677 248.348 1.00 47.70  ? 143 LEU   A CB    1 
ATOM   1613 C CG    . LEU   D 2 131 ? 253.974 192.368 249.754 1.00 45.47  ? 143 LEU   A CG    1 
ATOM   1614 C CD1   . LEU   D 2 131 ? 252.833 192.000 250.677 1.00 45.79  ? 143 LEU   A CD1   1 
ATOM   1615 C CD2   . LEU   D 2 131 ? 255.002 191.255 249.710 1.00 45.19  ? 143 LEU   A CD2   1 
ATOM   1616 N N     . ASN   D 2 132 ? 254.006 195.739 247.880 1.00 46.87  ? 144 ASN   A N     1 
ATOM   1617 C CA    . ASN   D 2 132 ? 254.644 196.991 248.271 1.00 46.91  ? 144 ASN   A CA    1 
ATOM   1618 C C     . ASN   D 2 132 ? 253.628 198.121 248.367 1.00 47.89  ? 144 ASN   A C     1 
ATOM   1619 O O     . ASN   D 2 132 ? 253.751 199.000 249.227 1.00 48.48  ? 144 ASN   A O     1 
ATOM   1620 C CB    . ASN   D 2 132 ? 255.753 197.344 247.282 1.00 47.48  ? 144 ASN   A CB    1 
ATOM   1621 C CG    . ASN   D 2 132 ? 257.098 196.788 247.695 1.00 48.32  ? 144 ASN   A CG    1 
ATOM   1622 O OD1   . ASN   D 2 132 ? 257.568 197.032 248.803 1.00 56.76  ? 144 ASN   A OD1   1 
ATOM   1623 N ND2   . ASN   D 2 132 ? 257.726 196.035 246.803 1.00 45.53  ? 144 ASN   A ND2   1 
ATOM   1624 N N     . ASP   D 2 133 ? 252.629 198.122 247.484 1.00 49.69  ? 145 ASP   A N     1 
ATOM   1625 C CA    . ASP   D 2 133 ? 251.579 199.133 247.545 1.00 50.28  ? 145 ASP   A CA    1 
ATOM   1626 C C     . ASP   D 2 133 ? 250.760 199.000 248.819 1.00 47.48  ? 145 ASP   A C     1 
ATOM   1627 O O     . ASP   D 2 133 ? 250.408 200.005 249.446 1.00 48.20  ? 145 ASP   A O     1 
ATOM   1628 C CB    . ASP   D 2 133 ? 250.674 199.024 246.319 1.00 50.37  ? 145 ASP   A CB    1 
ATOM   1629 C CG    . ASP   D 2 133 ? 251.374 199.417 245.040 1.00 57.23  ? 145 ASP   A CG    1 
ATOM   1630 O OD1   . ASP   D 2 133 ? 252.385 200.142 245.112 1.00 60.75  ? 145 ASP   A OD1   1 
ATOM   1631 O OD2   . ASP   D 2 133 ? 250.914 198.999 243.959 1.00 57.11  ? 145 ASP   A OD2   1 
ATOM   1632 N N     . ALA   D 2 134 ? 250.436 197.769 249.210 1.00 46.41  ? 146 ALA   A N     1 
ATOM   1633 C CA    . ALA   D 2 134 ? 249.650 197.554 250.416 1.00 45.37  ? 146 ALA   A CA    1 
ATOM   1634 C C     . ALA   D 2 134 ? 250.455 197.756 251.691 1.00 45.11  ? 146 ALA   A C     1 
ATOM   1635 O O     . ALA   D 2 134 ? 249.864 198.000 252.746 1.00 47.69  ? 146 ALA   A O     1 
ATOM   1636 C CB    . ALA   D 2 134 ? 249.043 196.151 250.410 1.00 47.42  ? 146 ALA   A CB    1 
ATOM   1637 N N     . THR   D 2 135 ? 251.783 197.662 251.625 1.00 46.07  ? 147 THR   A N     1 
ATOM   1638 C CA    . THR   D 2 135 ? 252.612 197.783 252.819 1.00 46.02  ? 147 THR   A CA    1 
ATOM   1639 C C     . THR   D 2 135 ? 253.179 199.188 253.000 1.00 47.01  ? 147 THR   A C     1 
ATOM   1640 O O     . THR   D 2 135 ? 252.976 199.809 254.047 1.00 48.87  ? 147 THR   A O     1 
ATOM   1641 C CB    . THR   D 2 135 ? 253.752 196.757 252.778 1.00 46.28  ? 147 THR   A CB    1 
ATOM   1642 O OG1   . THR   D 2 135 ? 253.236 195.480 252.388 1.00 49.83  ? 147 THR   A OG1   1 
ATOM   1643 C CG2   . THR   D 2 135 ? 254.391 196.635 254.143 1.00 46.64  ? 147 THR   A CG2   1 
ATOM   1644 N N     . TYR   D 2 136 ? 253.883 199.705 252.000 1.00 47.96  ? 148 TYR   A N     1 
ATOM   1645 C CA    . TYR   D 2 136 ? 254.684 200.909 252.158 1.00 48.29  ? 148 TYR   A CA    1 
ATOM   1646 C C     . TYR   D 2 136 ? 254.114 202.065 251.349 1.00 50.54  ? 148 TYR   A C     1 
ATOM   1647 O O     . TYR   D 2 136 ? 253.664 201.886 250.214 1.00 49.71  ? 148 TYR   A O     1 
ATOM   1648 C CB    . TYR   D 2 136 ? 256.133 200.643 251.750 1.00 48.56  ? 148 TYR   A CB    1 
ATOM   1649 C CG    . TYR   D 2 136 ? 256.777 199.548 252.562 1.00 50.92  ? 148 TYR   A CG    1 
ATOM   1650 C CD1   . TYR   D 2 136 ? 257.000 199.708 253.920 1.00 53.86  ? 148 TYR   A CD1   1 
ATOM   1651 C CD2   . TYR   D 2 136 ? 257.142 198.345 251.978 1.00 51.15  ? 148 TYR   A CD2   1 
ATOM   1652 C CE1   . TYR   D 2 136 ? 257.580 198.708 254.669 1.00 56.70  ? 148 TYR   A CE1   1 
ATOM   1653 C CE2   . TYR   D 2 136 ? 257.723 197.340 252.720 1.00 52.65  ? 148 TYR   A CE2   1 
ATOM   1654 C CZ    . TYR   D 2 136 ? 257.939 197.528 254.066 1.00 57.63  ? 148 TYR   A CZ    1 
ATOM   1655 O OH    . TYR   D 2 136 ? 258.516 196.532 254.814 1.00 61.65  ? 148 TYR   A OH    1 
ATOM   1656 N N     . GLN   D 2 137 ? 254.139 203.250 251.948 1.00 52.23  ? 149 GLN   A N     1 
ATOM   1657 C CA    . GLN   D 2 137 ? 253.678 204.474 251.315 1.00 51.41  ? 149 GLN   A CA    1 
ATOM   1658 C C     . GLN   D 2 137 ? 254.832 205.169 250.601 1.00 53.40  ? 149 GLN   A C     1 
ATOM   1659 O O     . GLN   D 2 137 ? 255.995 205.044 250.992 1.00 53.77  ? 149 GLN   A O     1 
ATOM   1660 C CB    . GLN   D 2 137 ? 253.068 205.409 252.358 1.00 49.81  ? 149 GLN   A CB    1 
ATOM   1661 C CG    . GLN   D 2 137 ? 251.725 205.988 251.978 1.00 50.84  ? 149 GLN   A CG    1 
ATOM   1662 C CD    . GLN   D 2 137 ? 250.999 206.574 253.168 1.00 51.74  ? 149 GLN   A CD    1 
ATOM   1663 O OE1   . GLN   D 2 137 ? 251.000 206.000 254.254 1.00 47.27  ? 149 GLN   A OE1   1 
ATOM   1664 N NE2   . GLN   D 2 137 ? 250.376 207.726 252.970 1.00 53.31  ? 149 GLN   A NE2   1 
ATOM   1665 N N     . ARG   D 2 138 ? 254.497 205.912 249.551 1.00 52.07  ? 150 ARG   A N     1 
ATOM   1666 C CA    . ARG   D 2 138 ? 255.480 206.555 248.687 1.00 50.64  ? 150 ARG   A CA    1 
ATOM   1667 C C     . ARG   D 2 138 ? 255.367 208.072 248.749 1.00 53.78  ? 150 ARG   A C     1 
ATOM   1668 O O     . ARG   D 2 138 ? 255.446 208.760 247.730 1.00 58.09  ? 150 ARG   A O     1 
ATOM   1669 C CB    . ARG   D 2 138 ? 255.334 206.071 247.246 1.00 51.24  ? 150 ARG   A CB    1 
ATOM   1670 C CG    . ARG   D 2 138 ? 255.552 204.584 247.064 1.00 51.37  ? 150 ARG   A CG    1 
ATOM   1671 C CD    . ARG   D 2 138 ? 257.006 204.280 246.772 1.00 49.83  ? 150 ARG   A CD    1 
ATOM   1672 N NE    . ARG   D 2 138 ? 257.377 204.673 245.419 1.00 51.75  ? 150 ARG   A NE    1 
ATOM   1673 C CZ    . ARG   D 2 138 ? 258.606 205.000 245.046 1.00 52.50  ? 150 ARG   A CZ    1 
ATOM   1674 N NH1   . ARG   D 2 138 ? 259.611 204.999 245.904 1.00 50.29  ? 150 ARG   A NH1   1 
ATOM   1675 N NH2   . ARG   D 2 138 ? 258.831 205.334 243.780 1.00 58.40  ? 150 ARG   A NH2   1 
ATOM   1676 N N     . THR   D 2 139 ? 255.186 208.617 249.953 1.00 52.55  ? 151 THR   A N     1 
ATOM   1677 C CA    . THR   D 2 139 ? 254.974 210.055 250.079 1.00 54.49  ? 151 THR   A CA    1 
ATOM   1678 C C     . THR   D 2 139 ? 256.242 210.852 249.794 1.00 52.87  ? 151 THR   A C     1 
ATOM   1679 O O     . THR   D 2 139 ? 256.158 211.971 249.278 1.00 53.58  ? 151 THR   A O     1 
ATOM   1680 C CB    . THR   D 2 139 ? 254.447 210.389 251.471 1.00 53.43  ? 151 THR   A CB    1 
ATOM   1681 O OG1   . THR   D 2 139 ? 254.420 211.810 251.644 1.00 61.20  ? 151 THR   A OG1   1 
ATOM   1682 C CG2   . THR   D 2 139 ? 255.348 209.797 252.508 1.00 57.62  ? 151 THR   A CG2   1 
ATOM   1683 N N     . ARG   D 2 140 ? 257.415 210.308 250.127 1.00 51.81  ? 152 ARG   A N     1 
ATOM   1684 C CA    . ARG   D 2 140 ? 258.656 211.045 249.905 1.00 54.01  ? 152 ARG   A CA    1 
ATOM   1685 C C     . ARG   D 2 140 ? 258.909 211.266 248.419 1.00 53.64  ? 152 ARG   A C     1 
ATOM   1686 O O     . ARG   D 2 140 ? 259.263 212.375 248.000 1.00 54.23  ? 152 ARG   A O     1 
ATOM   1687 C CB    . ARG   D 2 140 ? 259.830 210.308 250.547 1.00 57.89  ? 152 ARG   A CB    1 
ATOM   1688 C CG    . ARG   D 2 140 ? 261.139 211.074 250.489 1.00 62.18  ? 152 ARG   A CG    1 
ATOM   1689 C CD    . ARG   D 2 140 ? 262.009 210.855 251.722 1.00 64.59  ? 152 ARG   A CD    1 
ATOM   1690 N NE    . ARG   D 2 140 ? 261.260 210.898 252.971 1.00 74.99  ? 152 ARG   A NE    1 
ATOM   1691 C CZ    . ARG   D 2 140 ? 260.874 209.828 253.652 1.00 84.28  ? 152 ARG   A CZ    1 
ATOM   1692 N NH1   . ARG   D 2 140 ? 261.144 208.605 253.228 1.00 80.38  ? 152 ARG   A NH1   1 
ATOM   1693 N NH2   . ARG   D 2 140 ? 260.200 209.990 254.787 1.00 89.80  ? 152 ARG   A NH2   1 
ATOM   1694 N N     . ALA   D 2 141 ? 258.718 210.224 247.607 1.00 54.29  ? 153 ALA   A N     1 
ATOM   1695 C CA    . ALA   D 2 141 ? 258.849 210.378 246.163 1.00 54.08  ? 153 ALA   A CA    1 
ATOM   1696 C C     . ALA   D 2 141 ? 257.801 211.339 245.617 1.00 51.97  ? 153 ALA   A C     1 
ATOM   1697 O O     . ALA   D 2 141 ? 258.079 212.113 244.696 1.00 52.39  ? 153 ALA   A O     1 
ATOM   1698 C CB    . ALA   D 2 141 ? 258.740 209.017 245.479 1.00 52.55  ? 153 ALA   A CB    1 
ATOM   1699 N N     . LEU   D 2 142 ? 256.589 211.297 246.172 1.00 51.61  ? 154 LEU   A N     1 
ATOM   1700 C CA    . LEU   D 2 142 ? 255.538 212.218 245.751 1.00 52.23  ? 154 LEU   A CA    1 
ATOM   1701 C C     . LEU   D 2 142 ? 255.943 213.665 245.997 1.00 52.37  ? 154 LEU   A C     1 
ATOM   1702 O O     . LEU   D 2 142 ? 255.796 214.524 245.121 1.00 52.80  ? 154 LEU   A O     1 
ATOM   1703 C CB    . LEU   D 2 142 ? 254.242 211.897 246.495 1.00 52.29  ? 154 LEU   A CB    1 
ATOM   1704 C CG    . LEU   D 2 142 ? 253.381 210.742 245.994 1.00 49.00  ? 154 LEU   A CG    1 
ATOM   1705 C CD1   . LEU   D 2 142 ? 252.540 210.177 247.119 1.00 51.78  ? 154 LEU   A CD1   1 
ATOM   1706 C CD2   . LEU   D 2 142 ? 252.491 211.234 244.890 1.00 53.04  ? 154 LEU   A CD2   1 
ATOM   1707 N N     . VAL   D 2 143 ? 256.458 213.950 247.193 1.00 52.86  ? 155 VAL   A N     1 
ATOM   1708 C CA    . VAL   D 2 143 ? 256.828 215.315 247.549 1.00 51.11  ? 155 VAL   A CA    1 
ATOM   1709 C C     . VAL   D 2 143 ? 258.032 215.772 246.739 1.00 51.87  ? 155 VAL   A C     1 
ATOM   1710 O O     . VAL   D 2 143 ? 258.123 216.940 246.343 1.00 56.18  ? 155 VAL   A O     1 
ATOM   1711 C CB    . VAL   D 2 143 ? 257.085 215.413 249.063 1.00 50.70  ? 155 VAL   A CB    1 
ATOM   1712 C CG1   . VAL   D 2 143 ? 257.612 216.787 249.431 1.00 49.20  ? 155 VAL   A CG1   1 
ATOM   1713 C CG2   . VAL   D 2 143 ? 255.813 215.113 249.830 1.00 53.08  ? 155 VAL   A CG2   1 
ATOM   1714 N N     . ARG   D 2 144 ? 258.974 214.863 246.475 1.00 49.41  ? 156 ARG   A N     1 
ATOM   1715 C CA    . ARG   D 2 144 ? 260.157 215.235 245.706 1.00 52.80  ? 156 ARG   A CA    1 
ATOM   1716 C C     . ARG   D 2 144 ? 259.788 215.675 244.293 1.00 54.02  ? 156 ARG   A C     1 
ATOM   1717 O O     . ARG   D 2 144 ? 260.363 216.633 243.765 1.00 55.72  ? 156 ARG   A O     1 
ATOM   1718 C CB    . ARG   D 2 144 ? 261.145 214.071 245.670 1.00 57.41  ? 156 ARG   A CB    1 
ATOM   1719 C CG    . ARG   D 2 144 ? 262.480 214.420 245.045 1.00 62.39  ? 156 ARG   A CG    1 
ATOM   1720 C CD    . ARG   D 2 144 ? 263.035 213.259 244.253 1.00 73.63  ? 156 ARG   A CD    1 
ATOM   1721 N NE    . ARG   D 2 144 ? 264.005 212.496 245.027 1.00 92.42  ? 156 ARG   A NE    1 
ATOM   1722 C CZ    . ARG   D 2 144 ? 263.880 211.210 245.324 1.00 103.84 ? 156 ARG   A CZ    1 
ATOM   1723 N NH1   . ARG   D 2 144 ? 262.831 210.508 244.928 1.00 95.89  ? 156 ARG   A NH1   1 
ATOM   1724 N NH2   . ARG   D 2 144 ? 264.831 210.613 246.037 1.00 108.42 ? 156 ARG   A NH2   1 
ATOM   1725 N N     . THR   D 2 145 ? 258.825 215.000 243.670 1.00 52.41  ? 157 THR   A N     1 
ATOM   1726 C CA    . THR   D 2 145 ? 258.412 215.350 242.316 1.00 53.63  ? 157 THR   A CA    1 
ATOM   1727 C C     . THR   D 2 145 ? 257.411 216.496 242.276 1.00 54.42  ? 157 THR   A C     1 
ATOM   1728 O O     . THR   D 2 145 ? 257.000 216.899 241.184 1.00 57.52  ? 157 THR   A O     1 
ATOM   1729 C CB    . THR   D 2 145 ? 257.820 214.130 241.606 1.00 53.46  ? 157 THR   A CB    1 
ATOM   1730 O OG1   . THR   D 2 145 ? 256.612 213.731 242.262 1.00 56.54  ? 157 THR   A OG1   1 
ATOM   1731 C CG2   . THR   D 2 145 ? 258.805 212.978 241.623 1.00 52.92  ? 157 THR   A CG2   1 
ATOM   1732 N N     . GLY   D 2 146 ? 257.011 217.028 243.425 1.00 53.25  ? 158 GLY   A N     1 
ATOM   1733 C CA    . GLY   D 2 146 ? 256.128 218.173 243.456 1.00 49.51  ? 158 GLY   A CA    1 
ATOM   1734 C C     . GLY   D 2 146 ? 254.654 217.856 243.448 1.00 53.28  ? 158 GLY   A C     1 
ATOM   1735 O O     . GLY   D 2 146 ? 253.847 218.750 243.174 1.00 59.34  ? 158 GLY   A O     1 
ATOM   1736 N N     . MET   D 2 147 ? 254.269 216.621 243.741 1.00 55.02  ? 159 MET   A N     1 
ATOM   1737 C CA    . MET   D 2 147 ? 252.870 216.233 243.786 1.00 51.71  ? 159 MET   A CA    1 
ATOM   1738 C C     . MET   D 2 147 ? 252.428 216.073 245.234 1.00 55.31  ? 159 MET   A C     1 
ATOM   1739 O O     . MET   D 2 147 ? 253.232 215.753 246.114 1.00 59.35  ? 159 MET   A O     1 
ATOM   1740 C CB    . MET   D 2 147 ? 252.632 214.938 243.002 1.00 53.56  ? 159 MET   A CB    1 
ATOM   1741 C CG    . MET   D 2 147 ? 252.995 215.058 241.531 1.00 61.96  ? 159 MET   A CG    1 
ATOM   1742 S SD    . MET   D 2 147 ? 253.000 213.516 240.598 1.00 74.19  ? 159 MET   A SD    1 
ATOM   1743 C CE    . MET   D 2 147 ? 251.995 212.471 241.635 1.00 55.35  ? 159 MET   A CE    1 
ATOM   1744 N N     . ASP   D 2 148 ? 251.147 216.319 245.473 1.00 56.39  ? 160 ASP   A N     1 
ATOM   1745 C CA    . ASP   D 2 148 ? 250.622 216.292 246.829 1.00 54.96  ? 160 ASP   A CA    1 
ATOM   1746 C C     . ASP   D 2 148 ? 250.765 214.889 247.413 1.00 56.07  ? 160 ASP   A C     1 
ATOM   1747 O O     . ASP   D 2 148 ? 250.554 213.899 246.707 1.00 56.47  ? 160 ASP   A O     1 
ATOM   1748 C CB    . ASP   D 2 148 ? 249.154 216.720 246.835 1.00 55.59  ? 160 ASP   A CB    1 
ATOM   1749 C CG    . ASP   D 2 148 ? 248.841 217.718 247.927 1.00 62.93  ? 160 ASP   A CG    1 
ATOM   1750 O OD1   . ASP   D 2 148 ? 249.789 218.283 248.507 1.00 69.05  ? 160 ASP   A OD1   1 
ATOM   1751 O OD2   . ASP   D 2 148 ? 247.645 217.945 248.199 1.00 62.03  ? 160 ASP   A OD2   1 
ATOM   1752 N N     . PRO   D 2 149 ? 251.133 214.761 248.689 1.00 57.81  ? 161 PRO   A N     1 
ATOM   1753 C CA    . PRO   D 2 149 ? 251.230 213.423 249.290 1.00 57.13  ? 161 PRO   A CA    1 
ATOM   1754 C C     . PRO   D 2 149 ? 249.886 212.741 249.466 1.00 56.29  ? 161 PRO   A C     1 
ATOM   1755 O O     . PRO   D 2 149 ? 249.854 211.568 249.855 1.00 54.44  ? 161 PRO   A O     1 
ATOM   1756 C CB    . PRO   D 2 149 ? 251.897 213.693 250.642 1.00 57.85  ? 161 PRO   A CB    1 
ATOM   1757 C CG    . PRO   D 2 149 ? 251.556 215.104 250.951 1.00 57.07  ? 161 PRO   A CG    1 
ATOM   1758 C CD    . PRO   D 2 149 ? 251.525 215.820 249.634 1.00 58.82  ? 161 PRO   A CD    1 
ATOM   1759 N N     . ARG   D 2 150 ? 248.784 213.434 249.192 1.00 59.68  ? 162 ARG   A N     1 
ATOM   1760 C CA    . ARG   D 2 150 ? 247.451 212.888 249.386 1.00 55.70  ? 162 ARG   A CA    1 
ATOM   1761 C C     . ARG   D 2 150 ? 246.928 212.119 248.180 1.00 54.93  ? 162 ARG   A C     1 
ATOM   1762 O O     . ARG   D 2 150 ? 245.884 211.469 248.291 1.00 53.93  ? 162 ARG   A O     1 
ATOM   1763 C CB    . ARG   D 2 150 ? 246.471 214.010 249.737 1.00 55.07  ? 162 ARG   A CB    1 
ATOM   1764 C CG    . ARG   D 2 150 ? 246.908 214.878 250.901 1.00 57.22  ? 162 ARG   A CG    1 
ATOM   1765 C CD    . ARG   D 2 150 ? 245.734 215.643 251.479 1.00 54.96  ? 162 ARG   A CD    1 
ATOM   1766 N NE    . ARG   D 2 150 ? 246.071 217.029 251.777 1.00 59.41  ? 162 ARG   A NE    1 
ATOM   1767 C CZ    . ARG   D 2 150 ? 245.920 218.034 250.926 1.00 64.75  ? 162 ARG   A CZ    1 
ATOM   1768 N NH1   . ARG   D 2 150 ? 245.446 217.841 249.707 1.00 66.30  ? 162 ARG   A NH1   1 
ATOM   1769 N NH2   . ARG   D 2 150 ? 246.253 219.262 251.307 1.00 66.56  ? 162 ARG   A NH2   1 
ATOM   1770 N N     . MET   D 2 151 ? 247.605 212.176 247.038 1.00 55.77  ? 163 MET   A N     1 
ATOM   1771 C CA    . MET   D 2 151 ? 247.198 211.351 245.901 1.00 56.53  ? 163 MET   A CA    1 
ATOM   1772 C C     . MET   D 2 151 ? 247.942 210.020 245.897 1.00 54.73  ? 163 MET   A C     1 
ATOM   1773 O O     . MET   D 2 151 ? 248.518 209.600 244.898 1.00 53.15  ? 163 MET   A O     1 
ATOM   1774 C CB    . MET   D 2 151 ? 247.404 212.101 244.590 1.00 56.75  ? 163 MET   A CB    1 
ATOM   1775 C CG    . MET   D 2 151 ? 248.580 213.044 244.565 1.00 56.69  ? 163 MET   A CG    1 
ATOM   1776 S SD    . MET   D 2 151 ? 248.709 213.966 243.021 1.00 70.11  ? 163 MET   A SD    1 
ATOM   1777 C CE    . MET   D 2 151 ? 247.482 215.238 243.278 1.00 48.65  ? 163 MET   A CE    1 
ATOM   1778 N N     . CYS   D 2 152 ? 247.916 209.341 247.041 1.00 56.83  ? 164 CYS   A N     1 
ATOM   1779 C CA    . CYS   D 2 152 ? 248.484 208.006 247.136 1.00 53.51  ? 164 CYS   A CA    1 
ATOM   1780 C C     . CYS   D 2 152 ? 247.587 206.954 246.504 1.00 52.42  ? 164 CYS   A C     1 
ATOM   1781 O O     . CYS   D 2 152 ? 248.076 205.884 246.132 1.00 54.63  ? 164 CYS   A O     1 
ATOM   1782 C CB    . CYS   D 2 152 ? 248.754 207.654 248.600 1.00 49.37  ? 164 CYS   A CB    1 
ATOM   1783 S SG    . CYS   D 2 152 ? 247.277 207.536 249.621 1.00 65.10  ? 164 CYS   A SG    1 
ATOM   1784 N N     . SER   D 2 153 ? 246.293 207.243 246.360 1.00 50.61  ? 165 SER   A N     1 
ATOM   1785 C CA    . SER   D 2 153 ? 245.372 206.295 245.752 1.00 53.89  ? 165 SER   A CA    1 
ATOM   1786 C C     . SER   D 2 153 ? 245.642 206.092 244.268 1.00 52.45  ? 165 SER   A C     1 
ATOM   1787 O O     . SER   D 2 153 ? 245.214 205.079 243.706 1.00 51.92  ? 165 SER   A O     1 
ATOM   1788 C CB    . SER   D 2 153 ? 243.933 206.762 245.966 1.00 49.22  ? 165 SER   A CB    1 
ATOM   1789 O OG    . SER   D 2 153 ? 243.519 207.630 244.929 1.00 55.55  ? 165 SER   A OG    1 
ATOM   1790 N N     . LEU   D 2 154 ? 246.336 207.025 243.624 1.00 51.18  ? 166 LEU   A N     1 
ATOM   1791 C CA    . LEU   D 2 154 ? 246.694 206.902 242.219 1.00 51.23  ? 166 LEU   A CA    1 
ATOM   1792 C C     . LEU   D 2 154 ? 248.070 206.286 242.010 1.00 53.76  ? 166 LEU   A C     1 
ATOM   1793 O O     . LEU   D 2 154 ? 248.467 206.070 240.862 1.00 57.19  ? 166 LEU   A O     1 
ATOM   1794 C CB    . LEU   D 2 154 ? 246.644 208.272 241.540 1.00 48.97  ? 166 LEU   A CB    1 
ATOM   1795 C CG    . LEU   D 2 154 ? 245.575 209.250 242.020 1.00 47.93  ? 166 LEU   A CG    1 
ATOM   1796 C CD1   . LEU   D 2 154 ? 245.960 210.665 241.654 1.00 47.13  ? 166 LEU   A CD1   1 
ATOM   1797 C CD2   . LEU   D 2 154 ? 244.228 208.893 241.427 1.00 53.35  ? 166 LEU   A CD2   1 
ATOM   1798 N N     . MET   D 2 155 ? 248.800 205.990 243.085 1.00 53.55  ? 167 MET   A N     1 
ATOM   1799 C CA    . MET   D 2 155 ? 250.165 205.490 242.994 1.00 52.58  ? 167 MET   A CA    1 
ATOM   1800 C C     . MET   D 2 155 ? 250.245 203.971 242.990 1.00 53.28  ? 167 MET   A C     1 
ATOM   1801 O O     . MET   D 2 155 ? 251.234 203.405 243.472 1.00 53.34  ? 167 MET   A O     1 
ATOM   1802 C CB    . MET   D 2 155 ? 251.012 206.066 244.128 1.00 51.58  ? 167 MET   A CB    1 
ATOM   1803 C CG    . MET   D 2 155 ? 250.989 207.575 244.188 1.00 55.12  ? 167 MET   A CG    1 
ATOM   1804 S SD    . MET   D 2 155 ? 252.050 208.330 242.945 1.00 70.01  ? 167 MET   A SD    1 
ATOM   1805 C CE    . MET   D 2 155 ? 253.331 207.093 242.778 1.00 61.04  ? 167 MET   A CE    1 
ATOM   1806 N N     . GLN   D 2 156 ? 249.230 203.294 242.467 1.00 53.25  ? 168 GLN   A N     1 
ATOM   1807 C CA    . GLN   D 2 156 ? 249.293 201.847 242.333 1.00 53.21  ? 168 GLN   A CA    1 
ATOM   1808 C C     . GLN   D 2 156 ? 250.353 201.456 241.311 1.00 52.62  ? 168 GLN   A C     1 
ATOM   1809 O O     . GLN   D 2 156 ? 250.439 202.038 240.229 1.00 55.06  ? 168 GLN   A O     1 
ATOM   1810 C CB    . GLN   D 2 156 ? 247.932 201.296 241.919 1.00 49.26  ? 168 GLN   A CB    1 
ATOM   1811 C CG    . GLN   D 2 156 ? 247.808 199.796 242.048 1.00 50.31  ? 168 GLN   A CG    1 
ATOM   1812 C CD    . GLN   D 2 156 ? 246.694 199.241 241.197 1.00 57.43  ? 168 GLN   A CD    1 
ATOM   1813 O OE1   . GLN   D 2 156 ? 245.567 199.730 241.238 1.00 67.43  ? 168 GLN   A OE1   1 
ATOM   1814 N NE2   . GLN   D 2 156 ? 247.000 198.218 240.416 1.00 58.02  ? 168 GLN   A NE2   1 
ATOM   1815 N N     . GLY   D 2 157 ? 251.162 200.461 241.660 1.00 51.63  ? 169 GLY   A N     1 
ATOM   1816 C CA    . GLY   D 2 157 ? 252.201 200.000 240.761 1.00 51.42  ? 169 GLY   A CA    1 
ATOM   1817 C C     . GLY   D 2 157 ? 253.377 200.938 240.612 1.00 53.22  ? 169 GLY   A C     1 
ATOM   1818 O O     . GLY   D 2 157 ? 254.001 200.971 239.549 1.00 53.16  ? 169 GLY   A O     1 
ATOM   1819 N N     . SER   D 2 158 ? 253.702 201.704 241.652 1.00 55.80  ? 170 SER   A N     1 
ATOM   1820 C CA    . SER   D 2 158 ? 254.828 202.625 241.582 1.00 53.60  ? 170 SER   A CA    1 
ATOM   1821 C C     . SER   D 2 158 ? 256.174 201.920 241.668 1.00 52.07  ? 170 SER   A C     1 
ATOM   1822 O O     . SER   D 2 158 ? 257.184 202.492 241.245 1.00 54.52  ? 170 SER   A O     1 
ATOM   1823 C CB    . SER   D 2 158 ? 254.722 203.670 242.693 1.00 51.63  ? 170 SER   A CB    1 
ATOM   1824 O OG    . SER   D 2 158 ? 254.351 203.068 243.919 1.00 56.65  ? 170 SER   A OG    1 
ATOM   1825 N N     . THR   D 2 159 ? 256.216 200.702 242.198 1.00 53.41  ? 171 THR   A N     1 
ATOM   1826 C CA    . THR   D 2 159 ? 257.457 199.952 242.319 1.00 52.92  ? 171 THR   A CA    1 
ATOM   1827 C C     . THR   D 2 159 ? 257.694 199.001 241.153 1.00 54.35  ? 171 THR   A C     1 
ATOM   1828 O O     . THR   D 2 159 ? 258.700 198.285 241.153 1.00 57.57  ? 171 THR   A O     1 
ATOM   1829 C CB    . THR   D 2 159 ? 257.475 199.165 243.632 1.00 53.34  ? 171 THR   A CB    1 
ATOM   1830 O OG1   . THR   D 2 159 ? 256.254 198.430 243.767 1.00 56.95  ? 171 THR   A OG1   1 
ATOM   1831 C CG2   . THR   D 2 159 ? 257.619 200.109 244.808 1.00 51.70  ? 171 THR   A CG2   1 
ATOM   1832 N N     . LEU   D 2 160 ? 256.806 198.977 240.171 1.00 51.86  ? 172 LEU   A N     1 
ATOM   1833 C CA    . LEU   D 2 160 ? 256.988 198.098 239.023 1.00 49.82  ? 172 LEU   A CA    1 
ATOM   1834 C C     . LEU   D 2 160 ? 258.160 198.588 238.182 1.00 56.45  ? 172 LEU   A C     1 
ATOM   1835 O O     . LEU   D 2 160 ? 258.191 199.762 237.799 1.00 64.37  ? 172 LEU   A O     1 
ATOM   1836 C CB    . LEU   D 2 160 ? 255.720 198.057 238.177 1.00 51.04  ? 172 LEU   A CB    1 
ATOM   1837 C CG    . LEU   D 2 160 ? 254.767 196.887 238.402 1.00 51.79  ? 172 LEU   A CG    1 
ATOM   1838 C CD1   . LEU   D 2 160 ? 253.599 196.973 237.441 1.00 51.32  ? 172 LEU   A CD1   1 
ATOM   1839 C CD2   . LEU   D 2 160 ? 255.496 195.569 238.248 1.00 53.07  ? 172 LEU   A CD2   1 
ATOM   1840 N N     . PRO   D 2 161 ? 259.134 197.737 237.880 1.00 55.45  ? 173 PRO   A N     1 
ATOM   1841 C CA    . PRO   D 2 161 ? 260.254 198.169 237.037 1.00 56.71  ? 173 PRO   A CA    1 
ATOM   1842 C C     . PRO   D 2 161 ? 259.838 198.304 235.579 1.00 52.87  ? 173 PRO   A C     1 
ATOM   1843 O O     . PRO   D 2 161 ? 258.737 197.935 235.169 1.00 54.87  ? 173 PRO   A O     1 
ATOM   1844 C CB    . PRO   D 2 161 ? 261.304 197.072 237.232 1.00 54.32  ? 173 PRO   A CB    1 
ATOM   1845 C CG    . PRO   D 2 161 ? 260.566 195.908 237.751 1.00 49.95  ? 173 PRO   A CG    1 
ATOM   1846 C CD    . PRO   D 2 161 ? 259.338 196.395 238.446 1.00 48.69  ? 173 PRO   A CD    1 
ATOM   1847 N N     . ARG   D 2 162 ? 260.758 198.863 234.791 1.00 51.19  ? 174 ARG   A N     1 
ATOM   1848 C CA    . ARG   D 2 162 ? 260.457 199.208 233.405 1.00 53.17  ? 174 ARG   A CA    1 
ATOM   1849 C C     . ARG   D 2 162 ? 260.256 197.977 232.532 1.00 54.54  ? 174 ARG   A C     1 
ATOM   1850 O O     . ARG   D 2 162 ? 259.535 198.043 231.531 1.00 55.91  ? 174 ARG   A O     1 
ATOM   1851 C CB    . ARG   D 2 162 ? 261.576 200.071 232.829 1.00 54.94  ? 174 ARG   A CB    1 
ATOM   1852 C CG    . ARG   D 2 162 ? 261.460 201.544 233.144 1.00 54.19  ? 174 ARG   A CG    1 
ATOM   1853 C CD    . ARG   D 2 162 ? 262.829 202.185 233.209 1.00 61.19  ? 174 ARG   A CD    1 
ATOM   1854 N NE    . ARG   D 2 162 ? 263.339 202.525 231.887 1.00 64.36  ? 174 ARG   A NE    1 
ATOM   1855 C CZ    . ARG   D 2 162 ? 264.366 201.924 231.304 1.00 59.16  ? 174 ARG   A CZ    1 
ATOM   1856 N NH1   . ARG   D 2 162 ? 265.006 200.928 231.890 1.00 55.32  ? 174 ARG   A NH1   1 
ATOM   1857 N NH2   . ARG   D 2 162 ? 264.761 202.333 230.103 1.00 63.69  ? 174 ARG   A NH2   1 
ATOM   1858 N N     . ARG   D 2 163 ? 260.881 196.853 232.882 1.00 52.70  ? 175 ARG   A N     1 
ATOM   1859 C CA    . ARG   D 2 163 ? 260.826 195.672 232.029 1.00 51.79  ? 175 ARG   A CA    1 
ATOM   1860 C C     . ARG   D 2 163 ? 259.460 194.999 232.026 1.00 51.05  ? 175 ARG   A C     1 
ATOM   1861 O O     . ARG   D 2 163 ? 259.262 194.055 231.254 1.00 53.30  ? 175 ARG   A O     1 
ATOM   1862 C CB    . ARG   D 2 163 ? 261.900 194.675 232.456 1.00 50.56  ? 175 ARG   A CB    1 
ATOM   1863 C CG    . ARG   D 2 163 ? 262.126 194.637 233.947 1.00 55.31  ? 175 ARG   A CG    1 
ATOM   1864 C CD    . ARG   D 2 163 ? 263.071 193.525 234.335 1.00 54.48  ? 175 ARG   A CD    1 
ATOM   1865 N NE    . ARG   D 2 163 ? 263.708 193.801 235.616 1.00 56.83  ? 175 ARG   A NE    1 
ATOM   1866 C CZ    . ARG   D 2 163 ? 263.647 192.999 236.667 1.00 57.52  ? 175 ARG   A CZ    1 
ATOM   1867 N NH1   . ARG   D 2 163 ? 263.000 191.847 236.620 1.00 55.14  ? 175 ARG   A NH1   1 
ATOM   1868 N NH2   . ARG   D 2 163 ? 264.250 193.360 237.795 1.00 59.37  ? 175 ARG   A NH2   1 
ATOM   1869 N N     . SER   D 2 164 ? 258.527 195.441 232.871 1.00 52.82  ? 176 SER   A N     1 
ATOM   1870 C CA    . SER   D 2 164 ? 257.185 194.869 232.856 1.00 54.82  ? 176 SER   A CA    1 
ATOM   1871 C C     . SER   D 2 164 ? 256.494 195.114 231.520 1.00 55.48  ? 176 SER   A C     1 
ATOM   1872 O O     . SER   D 2 164 ? 255.830 194.221 230.983 1.00 55.78  ? 176 SER   A O     1 
ATOM   1873 C CB    . SER   D 2 164 ? 256.357 195.444 234.003 1.00 50.99  ? 176 SER   A CB    1 
ATOM   1874 O OG    . SER   D 2 164 ? 256.673 196.805 234.219 1.00 56.42  ? 176 SER   A OG    1 
ATOM   1875 N N     . GLY   D 2 165 ? 256.639 196.315 230.970 1.00 51.42  ? 177 GLY   A N     1 
ATOM   1876 C CA    . GLY   D 2 165 ? 256.080 196.596 229.663 1.00 50.33  ? 177 GLY   A CA    1 
ATOM   1877 C C     . GLY   D 2 165 ? 254.590 196.890 229.713 1.00 54.43  ? 177 GLY   A C     1 
ATOM   1878 O O     . GLY   D 2 165 ? 254.065 197.421 230.692 1.00 60.79  ? 177 GLY   A O     1 
ATOM   1879 N N     . ALA   D 2 166 ? 253.903 196.531 228.627 1.00 50.33  ? 178 ALA   A N     1 
ATOM   1880 C CA    . ALA   D 2 166 ? 252.486 196.855 228.502 1.00 53.23  ? 178 ALA   A CA    1 
ATOM   1881 C C     . ALA   D 2 166 ? 251.634 196.091 229.505 1.00 54.95  ? 178 ALA   A C     1 
ATOM   1882 O O     . ALA   D 2 166 ? 250.596 196.600 229.943 1.00 61.58  ? 178 ALA   A O     1 
ATOM   1883 C CB    . ALA   D 2 166 ? 252.007 196.574 227.080 1.00 60.10  ? 178 ALA   A CB    1 
ATOM   1884 N N     . ALA   D 2 167 ? 252.037 194.872 229.867 1.00 51.32  ? 179 ALA   A N     1 
ATOM   1885 C CA    . ALA   D 2 167 ? 251.286 194.121 230.866 1.00 54.03  ? 179 ALA   A CA    1 
ATOM   1886 C C     . ALA   D 2 167 ? 251.299 194.833 232.210 1.00 50.51  ? 179 ALA   A C     1 
ATOM   1887 O O     . ALA   D 2 167 ? 250.259 194.955 232.868 1.00 49.74  ? 179 ALA   A O     1 
ATOM   1888 C CB    . ALA   D 2 167 ? 251.855 192.710 231.000 1.00 58.20  ? 179 ALA   A CB    1 
ATOM   1889 N N     . GLY   D 2 168 ? 252.468 195.314 232.634 1.00 49.07  ? 180 GLY   A N     1 
ATOM   1890 C CA    . GLY   D 2 168 ? 252.544 196.067 233.871 1.00 50.57  ? 180 GLY   A CA    1 
ATOM   1891 C C     . GLY   D 2 168 ? 252.071 197.495 233.737 1.00 51.37  ? 180 GLY   A C     1 
ATOM   1892 O O     . GLY   D 2 168 ? 251.695 198.119 234.734 1.00 54.39  ? 180 GLY   A O     1 
ATOM   1893 N N     . ALA   D 2 169 ? 252.083 198.035 232.517 1.00 46.93  ? 181 ALA   A N     1 
ATOM   1894 C CA    . ALA   D 2 169 ? 251.621 199.402 232.309 1.00 45.74  ? 181 ALA   A CA    1 
ATOM   1895 C C     . ALA   D 2 169 ? 250.126 199.521 232.567 1.00 50.23  ? 181 ALA   A C     1 
ATOM   1896 O O     . ALA   D 2 169 ? 249.651 200.565 233.026 1.00 55.93  ? 181 ALA   A O     1 
ATOM   1897 C CB    . ALA   D 2 169 ? 251.963 199.864 230.894 1.00 47.02  ? 181 ALA   A CB    1 
ATOM   1898 N N     . ALA   D 2 170 ? 249.367 198.466 232.267 1.00 48.68  ? 182 ALA   A N     1 
ATOM   1899 C CA    . ALA   D 2 170 ? 247.937 198.481 232.546 1.00 49.35  ? 182 ALA   A CA    1 
ATOM   1900 C C     . ALA   D 2 170 ? 247.655 198.511 234.042 1.00 49.94  ? 182 ALA   A C     1 
ATOM   1901 O O     . ALA   D 2 170 ? 246.603 199.000 234.465 1.00 52.61  ? 182 ALA   A O     1 
ATOM   1902 C CB    . ALA   D 2 170 ? 247.265 197.268 231.904 1.00 47.61  ? 182 ALA   A CB    1 
ATOM   1903 N N     . VAL   D 2 171 ? 248.577 197.999 234.852 1.00 51.15  ? 183 VAL   A N     1 
ATOM   1904 C CA    . VAL   D 2 171 ? 248.366 197.905 236.292 1.00 52.19  ? 183 VAL   A CA    1 
ATOM   1905 C C     . VAL   D 2 171 ? 248.720 199.206 236.999 1.00 50.18  ? 183 VAL   A C     1 
ATOM   1906 O O     . VAL   D 2 171 ? 248.046 199.602 237.952 1.00 51.40  ? 183 VAL   A O     1 
ATOM   1907 C CB    . VAL   D 2 171 ? 249.171 196.716 236.854 1.00 52.12  ? 183 VAL   A CB    1 
ATOM   1908 C CG1   . VAL   D 2 171 ? 249.015 196.626 238.357 1.00 52.82  ? 183 VAL   A CG1   1 
ATOM   1909 C CG2   . VAL   D 2 171 ? 248.725 195.427 236.198 1.00 54.58  ? 183 VAL   A CG2   1 
ATOM   1910 N N     . LYS   D 2 172 ? 249.769 199.892 236.555 1.00 51.32  ? 184 LYS   A N     1 
ATOM   1911 C CA    . LYS   D 2 172 ? 250.178 201.120 237.220 1.00 54.64  ? 184 LYS   A CA    1 
ATOM   1912 C C     . LYS   D 2 172 ? 249.145 202.218 237.000 1.00 52.86  ? 184 LYS   A C     1 
ATOM   1913 O O     . LYS   D 2 172 ? 248.577 202.354 235.913 1.00 52.82  ? 184 LYS   A O     1 
ATOM   1914 C CB    . LYS   D 2 172 ? 251.554 201.569 236.729 1.00 50.99  ? 184 LYS   A CB    1 
ATOM   1915 C CG    . LYS   D 2 172 ? 251.684 201.707 235.233 1.00 51.99  ? 184 LYS   A CG    1 
ATOM   1916 C CD    . LYS   D 2 172 ? 253.132 201.944 234.831 1.00 54.60  ? 184 LYS   A CD    1 
ATOM   1917 C CE    . LYS   D 2 172 ? 254.081 201.030 235.584 1.00 48.33  ? 184 LYS   A CE    1 
ATOM   1918 N NZ    . LYS   D 2 172 ? 255.448 201.064 235.000 1.00 42.51  ? 184 LYS   A NZ    1 
ATOM   1919 N N     . GLY   D 2 173 ? 248.903 203.000 238.046 1.00 51.50  ? 185 GLY   A N     1 
ATOM   1920 C CA    . GLY   D 2 173 ? 247.840 203.978 238.046 1.00 50.03  ? 185 GLY   A CA    1 
ATOM   1921 C C     . GLY   D 2 173 ? 248.237 205.284 237.387 1.00 53.91  ? 185 GLY   A C     1 
ATOM   1922 O O     . GLY   D 2 173 ? 249.317 205.437 236.815 1.00 56.74  ? 185 GLY   A O     1 
ATOM   1923 N N     . VAL   D 2 174 ? 247.319 206.247 237.473 1.00 52.93  ? 186 VAL   A N     1 
ATOM   1924 C CA    . VAL   D 2 174 ? 247.553 207.562 236.886 1.00 51.10  ? 186 VAL   A CA    1 
ATOM   1925 C C     . VAL   D 2 174 ? 248.680 208.280 237.615 1.00 50.72  ? 186 VAL   A C     1 
ATOM   1926 O O     . VAL   D 2 174 ? 249.478 208.997 237.000 1.00 52.51  ? 186 VAL   A O     1 
ATOM   1927 C CB    . VAL   D 2 174 ? 246.253 208.385 236.898 1.00 48.71  ? 186 VAL   A CB    1 
ATOM   1928 C CG1   . VAL   D 2 174 ? 246.501 209.785 236.372 1.00 49.10  ? 186 VAL   A CG1   1 
ATOM   1929 C CG2   . VAL   D 2 174 ? 245.180 207.690 236.079 1.00 46.98  ? 186 VAL   A CG2   1 
ATOM   1930 N N     . GLY   D 2 175 ? 248.761 208.103 238.933 1.00 52.06  ? 187 GLY   A N     1 
ATOM   1931 C CA    . GLY   D 2 175 ? 249.772 208.807 239.703 1.00 53.26  ? 187 GLY   A CA    1 
ATOM   1932 C C     . GLY   D 2 175 ? 251.184 208.421 239.314 1.00 55.78  ? 187 GLY   A C     1 
ATOM   1933 O O     . GLY   D 2 175 ? 252.053 209.282 239.173 1.00 59.37  ? 187 GLY   A O     1 
ATOM   1934 N N     . THR   D 2 176 ? 251.434 207.123 239.130 1.00 54.18  ? 188 THR   A N     1 
ATOM   1935 C CA    . THR   D 2 176 ? 252.780 206.679 238.778 1.00 56.19  ? 188 THR   A CA    1 
ATOM   1936 C C     . THR   D 2 176 ? 253.176 207.155 237.387 1.00 52.96  ? 188 THR   A C     1 
ATOM   1937 O O     . THR   D 2 176 ? 254.317 207.577 237.171 1.00 54.95  ? 188 THR   A O     1 
ATOM   1938 C CB    . THR   D 2 176 ? 252.875 205.158 238.868 1.00 57.89  ? 188 THR   A CB    1 
ATOM   1939 O OG1   . THR   D 2 176 ? 252.290 204.573 237.700 1.00 61.17  ? 188 THR   A OG1   1 
ATOM   1940 C CG2   . THR   D 2 176 ? 252.140 204.665 240.087 1.00 55.90  ? 188 THR   A CG2   1 
ATOM   1941 N N     . MET   D 2 177 ? 252.250 207.089 236.430 1.00 52.39  ? 189 MET   A N     1 
ATOM   1942 C CA    . MET   D 2 177 ? 252.552 207.580 235.091 1.00 56.84  ? 189 MET   A CA    1 
ATOM   1943 C C     . MET   D 2 177 ? 252.821 209.078 235.101 1.00 55.44  ? 189 MET   A C     1 
ATOM   1944 O O     . MET   D 2 177 ? 253.762 209.554 234.452 1.00 56.69  ? 189 MET   A O     1 
ATOM   1945 C CB    . MET   D 2 177 ? 251.411 207.247 234.134 1.00 54.23  ? 189 MET   A CB    1 
ATOM   1946 C CG    . MET   D 2 177 ? 251.046 205.785 234.089 1.00 55.58  ? 189 MET   A CG    1 
ATOM   1947 S SD    . MET   D 2 177 ? 252.222 204.949 233.025 1.00 65.26  ? 189 MET   A SD    1 
ATOM   1948 C CE    . MET   D 2 177 ? 252.123 206.019 231.605 1.00 60.66  ? 189 MET   A CE    1 
ATOM   1949 N N     . VAL   D 2 178 ? 252.009 209.835 235.841 1.00 52.28  ? 190 VAL   A N     1 
ATOM   1950 C CA    . VAL   D 2 178 ? 252.240 211.270 235.960 1.00 51.04  ? 190 VAL   A CA    1 
ATOM   1951 C C     . VAL   D 2 178 ? 253.598 211.533 236.593 1.00 50.22  ? 190 VAL   A C     1 
ATOM   1952 O O     . VAL   D 2 178 ? 254.338 212.418 236.157 1.00 48.21  ? 190 VAL   A O     1 
ATOM   1953 C CB    . VAL   D 2 178 ? 251.098 211.933 236.752 1.00 52.09  ? 190 VAL   A CB    1 
ATOM   1954 C CG1   . VAL   D 2 178 ? 251.509 213.310 237.235 1.00 52.32  ? 190 VAL   A CG1   1 
ATOM   1955 C CG2   . VAL   D 2 178 ? 249.855 212.030 235.893 1.00 49.56  ? 190 VAL   A CG2   1 
ATOM   1956 N N     . MET   D 2 179 ? 253.952 210.756 237.619 1.00 51.78  ? 191 MET   A N     1 
ATOM   1957 C CA    . MET   D 2 179 ? 255.231 210.937 238.298 1.00 52.94  ? 191 MET   A CA    1 
ATOM   1958 C C     . MET   D 2 179 ? 256.402 210.677 237.360 1.00 50.30  ? 191 MET   A C     1 
ATOM   1959 O O     . MET   D 2 179 ? 257.385 211.425 237.359 1.00 48.01  ? 191 MET   A O     1 
ATOM   1960 C CB    . MET   D 2 179 ? 255.299 210.011 239.512 1.00 51.96  ? 191 MET   A CB    1 
ATOM   1961 C CG    . MET   D 2 179 ? 256.130 210.537 240.661 1.00 56.11  ? 191 MET   A CG    1 
ATOM   1962 S SD    . MET   D 2 179 ? 256.002 209.505 242.132 1.00 60.19  ? 191 MET   A SD    1 
ATOM   1963 C CE    . MET   D 2 179 ? 256.792 208.003 241.568 1.00 50.24  ? 191 MET   A CE    1 
ATOM   1964 N N     . GLU   D 2 180 ? 256.316 209.618 236.556 1.00 53.12  ? 192 GLU   A N     1 
ATOM   1965 C CA    . GLU   D 2 180 ? 257.390 209.314 235.615 1.00 51.42  ? 192 GLU   A CA    1 
ATOM   1966 C C     . GLU   D 2 180 ? 257.513 210.391 234.541 1.00 49.91  ? 192 GLU   A C     1 
ATOM   1967 O O     . GLU   D 2 180 ? 258.627 210.813 234.191 1.00 48.89  ? 192 GLU   A O     1 
ATOM   1968 C CB    . GLU   D 2 180 ? 257.149 207.945 234.991 1.00 49.57  ? 192 GLU   A CB    1 
ATOM   1969 C CG    . GLU   D 2 180 ? 257.743 206.797 235.778 1.00 57.66  ? 192 GLU   A CG    1 
ATOM   1970 C CD    . GLU   D 2 180 ? 256.906 205.545 235.693 1.00 63.24  ? 192 GLU   A CD    1 
ATOM   1971 O OE1   . GLU   D 2 180 ? 256.422 205.231 234.587 1.00 64.04  ? 192 GLU   A OE1   1 
ATOM   1972 O OE2   . GLU   D 2 180 ? 256.732 204.873 236.729 1.00 68.57  ? 192 GLU   A OE2   1 
ATOM   1973 N N     . LEU   D 2 181 ? 256.378 210.857 234.015 1.00 50.88  ? 193 LEU   A N     1 
ATOM   1974 C CA    . LEU   D 2 181 ? 256.417 211.940 233.039 1.00 48.83  ? 193 LEU   A CA    1 
ATOM   1975 C C     . LEU   D 2 181 ? 256.999 213.207 233.652 1.00 48.04  ? 193 LEU   A C     1 
ATOM   1976 O O     . LEU   D 2 181 ? 257.766 213.924 233.001 1.00 47.35  ? 193 LEU   A O     1 
ATOM   1977 C CB    . LEU   D 2 181 ? 255.016 212.193 232.487 1.00 49.89  ? 193 LEU   A CB    1 
ATOM   1978 C CG    . LEU   D 2 181 ? 254.443 211.077 231.612 1.00 50.78  ? 193 LEU   A CG    1 
ATOM   1979 C CD1   . LEU   D 2 181 ? 253.000 211.357 231.251 1.00 46.96  ? 193 LEU   A CD1   1 
ATOM   1980 C CD2   . LEU   D 2 181 ? 255.283 210.910 230.361 1.00 56.80  ? 193 LEU   A CD2   1 
ATOM   1981 N N     . ILE   D 2 182 ? 256.655 213.493 234.909 1.00 47.79  ? 194 ILE   A N     1 
ATOM   1982 C CA    . ILE   D 2 182 ? 257.165 214.682 235.581 1.00 47.29  ? 194 ILE   A CA    1 
ATOM   1983 C C     . ILE   D 2 182 ? 258.664 214.561 235.815 1.00 48.02  ? 194 ILE   A C     1 
ATOM   1984 O O     . ILE   D 2 182 ? 259.400 215.545 235.708 1.00 49.11  ? 194 ILE   A O     1 
ATOM   1985 C CB    . ILE   D 2 182 ? 256.395 214.925 236.893 1.00 48.90  ? 194 ILE   A CB    1 
ATOM   1986 C CG1   . ILE   D 2 182 ? 254.998 215.462 236.594 1.00 48.71  ? 194 ILE   A CG1   1 
ATOM   1987 C CG2   . ILE   D 2 182 ? 257.141 215.896 237.792 1.00 51.49  ? 194 ILE   A CG2   1 
ATOM   1988 C CD1   . ILE   D 2 182 ? 254.258 215.942 237.815 1.00 52.69  ? 194 ILE   A CD1   1 
ATOM   1989 N N     . ARG   D 2 183 ? 259.142 213.356 236.131 1.00 48.13  ? 195 ARG   A N     1 
ATOM   1990 C CA    . ARG   D 2 183 ? 260.582 213.140 236.236 1.00 46.84  ? 195 ARG   A CA    1 
ATOM   1991 C C     . ARG   D 2 183 ? 261.270 213.429 234.911 1.00 47.48  ? 195 ARG   A C     1 
ATOM   1992 O O     . ARG   D 2 183 ? 262.332 214.064 234.874 1.00 46.15  ? 195 ARG   A O     1 
ATOM   1993 C CB    . ARG   D 2 183 ? 260.874 211.706 236.673 1.00 47.44  ? 195 ARG   A CB    1 
ATOM   1994 C CG    . ARG   D 2 183 ? 260.576 211.406 238.121 1.00 52.73  ? 195 ARG   A CG    1 
ATOM   1995 C CD    . ARG   D 2 183 ? 261.535 210.361 238.651 1.00 53.49  ? 195 ARG   A CD    1 
ATOM   1996 N NE    . ARG   D 2 183 ? 261.001 209.663 239.812 1.00 56.50  ? 195 ARG   A NE    1 
ATOM   1997 C CZ    . ARG   D 2 183 ? 260.465 208.452 239.771 1.00 60.74  ? 195 ARG   A CZ    1 
ATOM   1998 N NH1   . ARG   D 2 183 ? 260.375 207.775 238.640 1.00 57.44  ? 195 ARG   A NH1   1 
ATOM   1999 N NH2   . ARG   D 2 183 ? 260.013 207.906 240.895 1.00 62.21  ? 195 ARG   A NH2   1 
ATOM   2000 N N     . MET   D 2 184 ? 260.673 212.968 233.811 1.00 49.96  ? 196 MET   A N     1 
ATOM   2001 C CA    . MET   D 2 184 ? 261.235 213.246 232.492 1.00 49.10  ? 196 MET   A CA    1 
ATOM   2002 C C     . MET   D 2 184 ? 261.268 214.745 232.208 1.00 51.10  ? 196 MET   A C     1 
ATOM   2003 O O     . MET   D 2 184 ? 262.269 215.271 231.704 1.00 50.58  ? 196 MET   A O     1 
ATOM   2004 C CB    . MET   D 2 184 ? 260.430 212.508 231.424 1.00 49.04  ? 196 MET   A CB    1 
ATOM   2005 C CG    . MET   D 2 184 ? 260.963 211.128 231.092 1.00 47.09  ? 196 MET   A CG    1 
ATOM   2006 S SD    . MET   D 2 184 ? 259.813 210.173 230.089 1.00 60.70  ? 196 MET   A SD    1 
ATOM   2007 C CE    . MET   D 2 184 ? 260.777 209.928 228.607 1.00 58.75  ? 196 MET   A CE    1 
ATOM   2008 N N     . ILE   D 2 185 ? 260.185 215.452 232.540 1.00 51.87  ? 197 ILE   A N     1 
ATOM   2009 C CA    . ILE   D 2 185 ? 260.135 216.893 232.300 1.00 48.47  ? 197 ILE   A CA    1 
ATOM   2010 C C     . ILE   D 2 185 ? 261.169 217.615 233.155 1.00 48.51  ? 197 ILE   A C     1 
ATOM   2011 O O     . ILE   D 2 185 ? 261.807 218.571 232.703 1.00 52.01  ? 197 ILE   A O     1 
ATOM   2012 C CB    . ILE   D 2 185 ? 258.719 217.447 232.551 1.00 50.30  ? 197 ILE   A CB    1 
ATOM   2013 C CG1   . ILE   D 2 185 ? 257.659 216.669 231.771 1.00 45.94  ? 197 ILE   A CG1   1 
ATOM   2014 C CG2   . ILE   D 2 185 ? 258.654 218.910 232.168 1.00 53.61  ? 197 ILE   A CG2   1 
ATOM   2015 C CD1   . ILE   D 2 185 ? 258.029 216.369 230.350 1.00 52.85  ? 197 ILE   A CD1   1 
ATOM   2016 N N     . LYS   D 2 186 ? 261.340 217.185 234.407 1.00 49.08  ? 198 LYS   A N     1 
ATOM   2017 C CA    . LYS   D 2 186 ? 262.335 217.799 235.281 1.00 47.87  ? 198 LYS   A CA    1 
ATOM   2018 C C     . LYS   D 2 186 ? 263.743 217.590 234.741 1.00 47.67  ? 198 LYS   A C     1 
ATOM   2019 O O     . LYS   D 2 186 ? 264.571 218.510 234.767 1.00 49.54  ? 198 LYS   A O     1 
ATOM   2020 C CB    . LYS   D 2 186 ? 262.218 217.227 236.694 1.00 49.61  ? 198 LYS   A CB    1 
ATOM   2021 C CG    . LYS   D 2 186 ? 260.956 217.620 237.441 1.00 46.01  ? 198 LYS   A CG    1 
ATOM   2022 C CD    . LYS   D 2 186 ? 260.846 219.117 237.622 1.00 52.10  ? 198 LYS   A CD    1 
ATOM   2023 C CE    . LYS   D 2 186 ? 260.000 219.452 238.836 1.00 54.51  ? 198 LYS   A CE    1 
ATOM   2024 N NZ    . LYS   D 2 186 ? 260.331 218.585 239.994 1.00 50.15  ? 198 LYS   A NZ    1 
ATOM   2025 N N     . ARG   D 2 187 ? 264.033 216.382 234.251 1.00 48.95  ? 199 ARG   A N     1 
ATOM   2026 C CA    . ARG   D 2 187 ? 265.335 216.125 233.646 1.00 50.98  ? 199 ARG   A CA    1 
ATOM   2027 C C     . ARG   D 2 187 ? 265.550 217.000 232.420 1.00 51.99  ? 199 ARG   A C     1 
ATOM   2028 O O     . ARG   D 2 187 ? 266.657 217.501 232.190 1.00 51.27  ? 199 ARG   A O     1 
ATOM   2029 C CB    . ARG   D 2 187 ? 265.465 214.651 233.273 1.00 48.56  ? 199 ARG   A CB    1 
ATOM   2030 C CG    . ARG   D 2 187 ? 265.862 213.738 234.412 1.00 43.05  ? 199 ARG   A CG    1 
ATOM   2031 C CD    . ARG   D 2 187 ? 265.814 212.296 233.955 1.00 47.36  ? 199 ARG   A CD    1 
ATOM   2032 N NE    . ARG   D 2 187 ? 266.005 211.353 235.048 1.00 52.47  ? 199 ARG   A NE    1 
ATOM   2033 C CZ    . ARG   D 2 187 ? 265.586 210.096 235.027 1.00 60.21  ? 199 ARG   A CZ    1 
ATOM   2034 N NH1   . ARG   D 2 187 ? 264.928 209.606 233.991 1.00 58.32  ? 199 ARG   A NH1   1 
ATOM   2035 N NH2   . ARG   D 2 187 ? 265.831 209.313 236.073 1.00 65.64  ? 199 ARG   A NH2   1 
ATOM   2036 N N     . GLY   D 2 188 ? 264.506 217.186 231.613 1.00 51.48  ? 200 GLY   A N     1 
ATOM   2037 C CA    . GLY   D 2 188 ? 264.622 218.079 230.472 1.00 49.62  ? 200 GLY   A CA    1 
ATOM   2038 C C     . GLY   D 2 188 ? 264.838 219.524 230.878 1.00 49.02  ? 200 GLY   A C     1 
ATOM   2039 O O     . GLY   D 2 188 ? 265.553 220.268 230.202 1.00 57.54  ? 200 GLY   A O     1 
ATOM   2040 N N     . ILE   D 2 189 ? 264.214 219.944 231.978 1.00 47.17  ? 201 ILE   A N     1 
ATOM   2041 C CA    . ILE   D 2 189 ? 264.356 221.320 232.442 1.00 50.06  ? 201 ILE   A CA    1 
ATOM   2042 C C     . ILE   D 2 189 ? 265.767 221.571 232.960 1.00 52.02  ? 201 ILE   A C     1 
ATOM   2043 O O     . ILE   D 2 189 ? 266.358 222.625 232.700 1.00 52.27  ? 201 ILE   A O     1 
ATOM   2044 C CB    . ILE   D 2 189 ? 263.290 221.631 233.508 1.00 48.33  ? 201 ILE   A CB    1 
ATOM   2045 C CG1   . ILE   D 2 189 ? 261.966 222.000 232.843 1.00 45.31  ? 201 ILE   A CG1   1 
ATOM   2046 C CG2   . ILE   D 2 189 ? 263.745 222.754 234.422 1.00 50.64  ? 201 ILE   A CG2   1 
ATOM   2047 C CD1   . ILE   D 2 189 ? 260.797 222.000 233.790 1.00 45.85  ? 201 ILE   A CD1   1 
ATOM   2048 N N     . ASN   D 2 190 ? 266.332 220.612 233.696 1.00 52.88  ? 202 ASN   A N     1 
ATOM   2049 C CA    . ASN   D 2 190 ? 267.683 220.792 234.223 1.00 51.82  ? 202 ASN   A CA    1 
ATOM   2050 C C     . ASN   D 2 190 ? 268.719 220.838 233.105 1.00 54.05  ? 202 ASN   A C     1 
ATOM   2051 O O     . ASN   D 2 190 ? 269.542 221.758 233.046 1.00 56.26  ? 202 ASN   A O     1 
ATOM   2052 C CB    . ASN   D 2 190 ? 268.016 219.675 235.210 1.00 49.05  ? 202 ASN   A CB    1 
ATOM   2053 C CG    . ASN   D 2 190 ? 267.000 219.559 236.318 1.00 58.41  ? 202 ASN   A CG    1 
ATOM   2054 O OD1   . ASN   D 2 190 ? 266.131 220.416 236.470 1.00 64.05  ? 202 ASN   A OD1   1 
ATOM   2055 N ND2   . ASN   D 2 190 ? 267.099 218.495 237.103 1.00 62.51  ? 202 ASN   A ND2   1 
ATOM   2056 N N     . ASP   D 2 191 ? 268.694 219.856 232.209 1.00 52.71  ? 203 ASP   A N     1 
ATOM   2057 C CA    . ASP   D 2 191 ? 269.678 219.738 231.140 1.00 52.48  ? 203 ASP   A CA    1 
ATOM   2058 C C     . ASP   D 2 191 ? 268.971 219.867 229.801 1.00 54.90  ? 203 ASP   A C     1 
ATOM   2059 O O     . ASP   D 2 191 ? 268.045 219.104 229.508 1.00 59.62  ? 203 ASP   A O     1 
ATOM   2060 C CB    . ASP   D 2 191 ? 270.420 218.404 231.223 1.00 55.97  ? 203 ASP   A CB    1 
ATOM   2061 C CG    . ASP   D 2 191 ? 271.661 218.374 230.360 1.00 58.83  ? 203 ASP   A CG    1 
ATOM   2062 O OD1   . ASP   D 2 191 ? 272.000 219.416 229.766 1.00 62.08  ? 203 ASP   A OD1   1 
ATOM   2063 O OD2   . ASP   D 2 191 ? 272.298 217.305 230.272 1.00 61.63  ? 203 ASP   A OD2   1 
ATOM   2064 N N     . ARG   D 2 192 ? 269.411 220.826 228.988 1.00 54.46  ? 204 ARG   A N     1 
ATOM   2065 C CA    . ARG   D 2 192 ? 268.812 221.005 227.674 1.00 52.00  ? 204 ARG   A CA    1 
ATOM   2066 C C     . ARG   D 2 192 ? 269.228 219.910 226.703 1.00 54.53  ? 204 ARG   A C     1 
ATOM   2067 O O     . ARG   D 2 192 ? 268.532 219.684 225.709 1.00 54.94  ? 204 ARG   A O     1 
ATOM   2068 C CB    . ARG   D 2 192 ? 269.181 222.380 227.117 1.00 56.40  ? 204 ARG   A CB    1 
ATOM   2069 C CG    . ARG   D 2 192 ? 268.297 222.861 225.983 1.00 54.68  ? 204 ARG   A CG    1 
ATOM   2070 C CD    . ARG   D 2 192 ? 267.880 224.303 226.190 1.00 50.35  ? 204 ARG   A CD    1 
ATOM   2071 N NE    . ARG   D 2 192 ? 267.855 225.047 224.937 1.00 53.45  ? 204 ARG   A NE    1 
ATOM   2072 C CZ    . ARG   D 2 192 ? 266.761 225.281 224.226 1.00 59.49  ? 204 ARG   A CZ    1 
ATOM   2073 N NH1   . ARG   D 2 192 ? 265.579 224.823 224.604 1.00 56.99  ? 204 ARG   A NH1   1 
ATOM   2074 N NH2   . ARG   D 2 192 ? 266.855 225.994 223.107 1.00 52.96  ? 204 ARG   A NH2   1 
ATOM   2075 N N     . ASN   D 2 193 ? 270.341 219.223 226.969 1.00 56.86  ? 205 ASN   A N     1 
ATOM   2076 C CA    . ASN   D 2 193 ? 270.780 218.127 226.114 1.00 54.38  ? 205 ASN   A CA    1 
ATOM   2077 C C     . ASN   D 2 193 ? 269.864 216.916 226.204 1.00 54.10  ? 205 ASN   A C     1 
ATOM   2078 O O     . ASN   D 2 193 ? 269.984 216.006 225.378 1.00 57.14  ? 205 ASN   A O     1 
ATOM   2079 C CB    . ASN   D 2 193 ? 272.212 217.729 226.465 1.00 56.93  ? 205 ASN   A CB    1 
ATOM   2080 C CG    . ASN   D 2 193 ? 273.212 218.209 225.437 1.00 53.87  ? 205 ASN   A CG    1 
ATOM   2081 O OD1   . ASN   D 2 193 ? 272.864 218.937 224.510 1.00 50.10  ? 205 ASN   A OD1   1 
ATOM   2082 N ND2   . ASN   D 2 193 ? 274.464 217.806 225.598 1.00 55.21  ? 205 ASN   A ND2   1 
ATOM   2083 N N     . PHE   D 2 194 ? 268.976 216.875 227.192 1.00 53.84  ? 206 PHE   A N     1 
ATOM   2084 C CA    . PHE   D 2 194 ? 267.840 215.969 227.141 1.00 54.72  ? 206 PHE   A CA    1 
ATOM   2085 C C     . PHE   D 2 194 ? 266.982 216.315 225.930 1.00 58.70  ? 206 PHE   A C     1 
ATOM   2086 O O     . PHE   D 2 194 ? 266.873 217.478 225.534 1.00 61.02  ? 206 PHE   A O     1 
ATOM   2087 C CB    . PHE   D 2 194 ? 267.021 216.082 228.428 1.00 54.75  ? 206 PHE   A CB    1 
ATOM   2088 C CG    . PHE   D 2 194 ? 266.386 214.795 228.871 1.00 50.62  ? 206 PHE   A CG    1 
ATOM   2089 C CD1   . PHE   D 2 194 ? 267.105 213.869 229.598 1.00 54.61  ? 206 PHE   A CD1   1 
ATOM   2090 C CD2   . PHE   D 2 194 ? 265.060 214.526 228.583 1.00 52.65  ? 206 PHE   A CD2   1 
ATOM   2091 C CE1   . PHE   D 2 194 ? 266.518 212.691 230.016 1.00 60.01  ? 206 PHE   A CE1   1 
ATOM   2092 C CE2   . PHE   D 2 194 ? 264.469 213.350 229.001 1.00 50.64  ? 206 PHE   A CE2   1 
ATOM   2093 C CZ    . PHE   D 2 194 ? 265.198 212.433 229.717 1.00 50.97  ? 206 PHE   A CZ    1 
ATOM   2094 N N     . TRP   D 2 195 ? 266.385 215.289 225.327 1.00 54.51  ? 207 TRP   A N     1 
ATOM   2095 C CA    . TRP   D 2 195 ? 265.627 215.396 224.082 1.00 55.64  ? 207 TRP   A CA    1 
ATOM   2096 C C     . TRP   D 2 195 ? 266.495 215.779 222.888 1.00 56.35  ? 207 TRP   A C     1 
ATOM   2097 O O     . TRP   D 2 195 ? 265.968 216.214 221.861 1.00 59.30  ? 207 TRP   A O     1 
ATOM   2098 C CB    . TRP   D 2 195 ? 264.459 216.390 224.181 1.00 53.69  ? 207 TRP   A CB    1 
ATOM   2099 C CG    . TRP   D 2 195 ? 263.723 216.428 225.483 1.00 55.01  ? 207 TRP   A CG    1 
ATOM   2100 C CD1   . TRP   D 2 195 ? 263.864 217.354 226.473 1.00 53.01  ? 207 TRP   A CD1   1 
ATOM   2101 C CD2   . TRP   D 2 195 ? 262.694 215.532 225.917 1.00 53.55  ? 207 TRP   A CD2   1 
ATOM   2102 N NE1   . TRP   D 2 195 ? 263.002 217.079 227.505 1.00 50.22  ? 207 TRP   A NE1   1 
ATOM   2103 C CE2   . TRP   D 2 195 ? 262.272 215.965 227.187 1.00 52.99  ? 207 TRP   A CE2   1 
ATOM   2104 C CE3   . TRP   D 2 195 ? 262.096 214.400 225.358 1.00 51.26  ? 207 TRP   A CE3   1 
ATOM   2105 C CZ2   . TRP   D 2 195 ? 261.283 215.304 227.909 1.00 52.06  ? 207 TRP   A CZ2   1 
ATOM   2106 C CZ3   . TRP   D 2 195 ? 261.114 213.748 226.076 1.00 51.21  ? 207 TRP   A CZ3   1 
ATOM   2107 C CH2   . TRP   D 2 195 ? 260.718 214.200 227.337 1.00 50.95  ? 207 TRP   A CH2   1 
ATOM   2108 N N     . ARG   D 2 196 ? 267.815 215.632 222.984 1.00 54.56  ? 208 ARG   A N     1 
ATOM   2109 C CA    . ARG   D 2 196 ? 268.706 215.873 221.857 1.00 52.35  ? 208 ARG   A CA    1 
ATOM   2110 C C     . ARG   D 2 196 ? 269.579 214.649 221.622 1.00 55.56  ? 208 ARG   A C     1 
ATOM   2111 O O     . ARG   D 2 196 ? 269.952 213.944 222.561 1.00 60.49  ? 208 ARG   A O     1 
ATOM   2112 C CB    . ARG   D 2 196 ? 269.604 217.107 222.064 1.00 53.21  ? 208 ARG   A CB    1 
ATOM   2113 C CG    . ARG   D 2 196 ? 268.886 218.455 222.094 1.00 61.88  ? 208 ARG   A CG    1 
ATOM   2114 C CD    . ARG   D 2 196 ? 269.849 219.634 222.254 1.00 57.66  ? 208 ARG   A CD    1 
ATOM   2115 N NE    . ARG   D 2 196 ? 269.190 220.933 222.356 1.00 56.06  ? 208 ARG   A NE    1 
ATOM   2116 C CZ    . ARG   D 2 196 ? 269.796 222.086 222.612 1.00 55.64  ? 208 ARG   A CZ    1 
ATOM   2117 N NH1   . ARG   D 2 196 ? 271.094 222.151 222.854 1.00 45.46  ? 208 ARG   A NH1   1 
ATOM   2118 N NH2   . ARG   D 2 196 ? 269.076 223.204 222.635 1.00 51.66  ? 208 ARG   A NH2   1 
ATOM   2119 N N     . GLY   D 2 197 ? 269.906 214.410 220.355 1.00 52.19  ? 209 GLY   A N     1 
ATOM   2120 C CA    . GLY   D 2 197 ? 270.701 213.261 219.982 1.00 49.15  ? 209 GLY   A CA    1 
ATOM   2121 C C     . GLY   D 2 197 ? 269.861 212.011 219.793 1.00 59.85  ? 209 GLY   A C     1 
ATOM   2122 O O     . GLY   D 2 197 ? 268.626 212.033 219.805 1.00 69.41  ? 209 GLY   A O     1 
ATOM   2123 N N     . GLU   D 2 198 ? 270.564 210.892 219.598 1.00 53.10  ? 210 GLU   A N     1 
ATOM   2124 C CA    . GLU   D 2 198 ? 269.881 209.609 219.473 1.00 54.30  ? 210 GLU   A CA    1 
ATOM   2125 C C     . GLU   D 2 198 ? 269.145 209.257 220.758 1.00 57.29  ? 210 GLU   A C     1 
ATOM   2126 O O     . GLU   D 2 198 ? 268.007 208.768 220.723 1.00 58.16  ? 210 GLU   A O     1 
ATOM   2127 C CB    . GLU   D 2 198 ? 270.885 208.517 219.112 1.00 55.81  ? 210 GLU   A CB    1 
ATOM   2128 C CG    . GLU   D 2 198 ? 271.643 208.782 217.829 1.00 64.97  ? 210 GLU   A CG    1 
ATOM   2129 C CD    . GLU   D 2 198 ? 271.000 208.123 216.631 1.00 81.97  ? 210 GLU   A CD    1 
ATOM   2130 O OE1   . GLU   D 2 198 ? 269.804 207.774 216.715 1.00 82.07  ? 210 GLU   A OE1   1 
ATOM   2131 O OE2   . GLU   D 2 198 ? 271.688 207.954 215.603 1.00 92.89  ? 210 GLU   A OE2   1 
ATOM   2132 N N     . ASN   D 2 199 ? 269.785 209.493 221.906 1.00 57.22  ? 211 ASN   A N     1 
ATOM   2133 C CA    . ASN   D 2 199 ? 269.095 209.344 223.179 1.00 56.33  ? 211 ASN   A CA    1 
ATOM   2134 C C     . ASN   D 2 199 ? 267.893 210.268 223.259 1.00 57.43  ? 211 ASN   A C     1 
ATOM   2135 O O     . ASN   D 2 199 ? 266.868 209.903 223.841 1.00 57.98  ? 211 ASN   A O     1 
ATOM   2136 C CB    . ASN   D 2 199 ? 270.052 209.620 224.336 1.00 53.12  ? 211 ASN   A CB    1 
ATOM   2137 C CG    . ASN   D 2 199 ? 270.543 208.355 225.000 1.00 56.98  ? 211 ASN   A CG    1 
ATOM   2138 O OD1   . ASN   D 2 199 ? 269.980 207.905 225.995 1.00 56.14  ? 211 ASN   A OD1   1 
ATOM   2139 N ND2   . ASN   D 2 199 ? 271.601 207.773 224.453 1.00 64.21  ? 211 ASN   A ND2   1 
ATOM   2140 N N     . GLY   D 2 200 ? 268.000 211.463 222.678 1.00 54.09  ? 212 GLY   A N     1 
ATOM   2141 C CA    . GLY   D 2 200 ? 266.861 212.361 222.645 1.00 53.85  ? 212 GLY   A CA    1 
ATOM   2142 C C     . GLY   D 2 200 ? 265.698 211.802 221.852 1.00 57.13  ? 212 GLY   A C     1 
ATOM   2143 O O     . GLY   D 2 200 ? 264.544 211.909 222.267 1.00 60.13  ? 212 GLY   A O     1 
ATOM   2144 N N     . ARG   D 2 201 ? 265.982 211.200 220.696 1.00 56.32  ? 213 ARG   A N     1 
ATOM   2145 C CA    . ARG   D 2 201 ? 264.914 210.588 219.912 1.00 57.72  ? 213 ARG   A CA    1 
ATOM   2146 C C     . ARG   D 2 201 ? 264.283 209.423 220.664 1.00 55.00  ? 213 ARG   A C     1 
ATOM   2147 O O     . ARG   D 2 201 ? 263.053 209.277 220.687 1.00 55.22  ? 213 ARG   A O     1 
ATOM   2148 C CB    . ARG   D 2 201 ? 265.451 210.128 218.557 1.00 58.55  ? 213 ARG   A CB    1 
ATOM   2149 C CG    . ARG   D 2 201 ? 264.390 209.584 217.615 1.00 59.04  ? 213 ARG   A CG    1 
ATOM   2150 C CD    . ARG   D 2 201 ? 265.002 209.099 216.305 1.00 77.19  ? 213 ARG   A CD    1 
ATOM   2151 N NE    . ARG   D 2 201 ? 265.597 210.187 215.535 1.00 83.45  ? 213 ARG   A NE    1 
ATOM   2152 C CZ    . ARG   D 2 201 ? 264.926 210.985 214.717 1.00 63.21  ? 213 ARG   A CZ    1 
ATOM   2153 N NH1   . ARG   D 2 201 ? 263.621 210.852 214.536 1.00 44.18  ? 213 ARG   A NH1   1 
ATOM   2154 N NH2   . ARG   D 2 201 ? 265.578 211.942 214.065 1.00 46.39  ? 213 ARG   A NH2   1 
ATOM   2155 N N     . ARG   D 2 202 ? 265.113 208.594 221.298 1.00 55.78  ? 214 ARG   A N     1 
ATOM   2156 C CA    . ARG   D 2 202 ? 264.591 207.462 222.057 1.00 54.52  ? 214 ARG   A CA    1 
ATOM   2157 C C     . ARG   D 2 202 ? 263.716 207.927 223.215 1.00 53.96  ? 214 ARG   A C     1 
ATOM   2158 O O     . ARG   D 2 202 ? 262.640 207.366 223.457 1.00 54.20  ? 214 ARG   A O     1 
ATOM   2159 C CB    . ARG   D 2 202 ? 265.743 206.601 222.567 1.00 53.84  ? 214 ARG   A CB    1 
ATOM   2160 C CG    . ARG   D 2 202 ? 266.520 205.903 221.472 1.00 54.62  ? 214 ARG   A CG    1 
ATOM   2161 C CD    . ARG   D 2 202 ? 267.833 205.361 222.000 1.00 58.52  ? 214 ARG   A CD    1 
ATOM   2162 N NE    . ARG   D 2 202 ? 268.084 203.997 221.554 1.00 63.97  ? 214 ARG   A NE    1 
ATOM   2163 C CZ    . ARG   D 2 202 ? 267.437 202.929 222.000 1.00 77.06  ? 214 ARG   A CZ    1 
ATOM   2164 N NH1   . ARG   D 2 202 ? 266.492 203.026 222.920 1.00 77.29  ? 214 ARG   A NH1   1 
ATOM   2165 N NH2   . ARG   D 2 202 ? 267.748 201.732 221.512 1.00 86.78  ? 214 ARG   A NH2   1 
ATOM   2166 N N     . THR   D 2 203 ? 264.152 208.961 223.937 1.00 51.92  ? 215 THR   A N     1 
ATOM   2167 C CA    . THR   D 2 203 ? 263.371 209.437 225.070 1.00 52.36  ? 215 THR   A CA    1 
ATOM   2168 C C     . THR   D 2 203 ? 262.120 210.179 224.614 1.00 51.61  ? 215 THR   A C     1 
ATOM   2169 O O     . THR   D 2 203 ? 261.106 210.152 225.313 1.00 52.60  ? 215 THR   A O     1 
ATOM   2170 C CB    . THR   D 2 203 ? 264.239 210.309 225.985 1.00 52.05  ? 215 THR   A CB    1 
ATOM   2171 O OG1   . THR   D 2 203 ? 263.553 210.538 227.221 1.00 62.88  ? 215 THR   A OG1   1 
ATOM   2172 C CG2   . THR   D 2 203 ? 264.553 211.641 225.348 1.00 53.08  ? 215 THR   A CG2   1 
ATOM   2173 N N     . ARG   D 2 204 ? 262.156 210.817 223.442 1.00 52.55  ? 216 ARG   A N     1 
ATOM   2174 C CA    . ARG   D 2 204 ? 260.941 211.399 222.881 1.00 52.83  ? 216 ARG   A CA    1 
ATOM   2175 C C     . ARG   D 2 204 ? 259.927 210.316 222.540 1.00 52.19  ? 216 ARG   A C     1 
ATOM   2176 O O     . ARG   D 2 204 ? 258.728 210.474 222.797 1.00 52.06  ? 216 ARG   A O     1 
ATOM   2177 C CB    . ARG   D 2 204 ? 261.288 212.229 221.644 1.00 52.94  ? 216 ARG   A CB    1 
ATOM   2178 C CG    . ARG   D 2 204 ? 260.128 213.000 221.044 1.00 51.95  ? 216 ARG   A CG    1 
ATOM   2179 C CD    . ARG   D 2 204 ? 259.476 213.913 222.058 1.00 48.12  ? 216 ARG   A CD    1 
ATOM   2180 N NE    . ARG   D 2 204 ? 258.048 214.053 221.805 1.00 53.79  ? 216 ARG   A NE    1 
ATOM   2181 C CZ    . ARG   D 2 204 ? 257.298 215.046 222.263 1.00 53.45  ? 216 ARG   A CZ    1 
ATOM   2182 N NH1   . ARG   D 2 204 ? 257.810 216.015 223.000 1.00 57.35  ? 216 ARG   A NH1   1 
ATOM   2183 N NH2   . ARG   D 2 204 ? 256.000 215.061 221.978 1.00 54.70  ? 216 ARG   A NH2   1 
ATOM   2184 N N     . ILE   D 2 205 ? 260.395 209.204 221.971 1.00 53.07  ? 217 ILE   A N     1 
ATOM   2185 C CA    . ILE   D 2 205 ? 259.507 208.081 221.681 1.00 50.63  ? 217 ILE   A CA    1 
ATOM   2186 C C     . ILE   D 2 205 ? 258.923 207.515 222.970 1.00 50.47  ? 217 ILE   A C     1 
ATOM   2187 O O     . ILE   D 2 205 ? 257.727 207.204 223.047 1.00 50.94  ? 217 ILE   A O     1 
ATOM   2188 C CB    . ILE   D 2 205 ? 260.259 207.009 220.872 1.00 48.09  ? 217 ILE   A CB    1 
ATOM   2189 C CG1   . ILE   D 2 205 ? 260.370 207.434 219.409 1.00 44.97  ? 217 ILE   A CG1   1 
ATOM   2190 C CG2   . ILE   D 2 205 ? 259.572 205.661 220.985 1.00 54.91  ? 217 ILE   A CG2   1 
ATOM   2191 C CD1   . ILE   D 2 205 ? 261.477 206.746 218.662 1.00 50.42  ? 217 ILE   A CD1   1 
ATOM   2192 N N     . ALA   D 2 206 ? 259.760 207.372 224.001 1.00 51.53  ? 218 ALA   A N     1 
ATOM   2193 C CA    . ALA   D 2 206 ? 259.277 206.885 225.290 1.00 52.92  ? 218 ALA   A CA    1 
ATOM   2194 C C     . ALA   D 2 206 ? 258.238 207.828 225.887 1.00 54.28  ? 218 ALA   A C     1 
ATOM   2195 O O     . ALA   D 2 206 ? 257.218 207.382 226.423 1.00 55.78  ? 218 ALA   A O     1 
ATOM   2196 C CB    . ALA   D 2 206 ? 260.451 206.703 226.250 1.00 49.72  ? 218 ALA   A CB    1 
ATOM   2197 N N     . TYR   D 2 207 ? 258.487 209.134 225.805 1.00 54.16  ? 219 TYR   A N     1 
ATOM   2198 C CA    . TYR   D 2 207 ? 257.550 210.125 226.318 1.00 53.33  ? 219 TYR   A CA    1 
ATOM   2199 C C     . TYR   D 2 207 ? 256.218 210.056 225.583 1.00 52.77  ? 219 TYR   A C     1 
ATOM   2200 O O     . TYR   D 2 207 ? 255.153 210.098 226.209 1.00 53.95  ? 219 TYR   A O     1 
ATOM   2201 C CB    . TYR   D 2 207 ? 258.182 211.512 226.196 1.00 52.62  ? 219 TYR   A CB    1 
ATOM   2202 C CG    . TYR   D 2 207 ? 257.312 212.685 226.575 1.00 52.64  ? 219 TYR   A CG    1 
ATOM   2203 C CD1   . TYR   D 2 207 ? 257.063 212.992 227.902 1.00 54.41  ? 219 TYR   A CD1   1 
ATOM   2204 C CD2   . TYR   D 2 207 ? 256.776 213.514 225.602 1.00 55.55  ? 219 TYR   A CD2   1 
ATOM   2205 C CE1   . TYR   D 2 207 ? 256.282 214.076 228.246 1.00 58.53  ? 219 TYR   A CE1   1 
ATOM   2206 C CE2   . TYR   D 2 207 ? 255.998 214.598 225.937 1.00 56.65  ? 219 TYR   A CE2   1 
ATOM   2207 C CZ    . TYR   D 2 207 ? 255.754 214.875 227.259 1.00 57.17  ? 219 TYR   A CZ    1 
ATOM   2208 O OH    . TYR   D 2 207 ? 254.976 215.957 227.593 1.00 56.54  ? 219 TYR   A OH    1 
ATOM   2209 N N     . GLU   D 2 208 ? 256.260 209.930 224.255 1.00 52.20  ? 220 GLU   A N     1 
ATOM   2210 C CA    . GLU   D 2 208 ? 255.030 209.808 223.480 1.00 51.99  ? 220 GLU   A CA    1 
ATOM   2211 C C     . GLU   D 2 208 ? 254.261 208.548 223.854 1.00 51.08  ? 220 GLU   A C     1 
ATOM   2212 O O     . GLU   D 2 208 ? 253.036 208.585 224.012 1.00 49.29  ? 220 GLU   A O     1 
ATOM   2213 C CB    . GLU   D 2 208 ? 255.350 209.809 221.987 1.00 54.53  ? 220 GLU   A CB    1 
ATOM   2214 C CG    . GLU   D 2 208 ? 255.802 211.146 221.448 1.00 56.66  ? 220 GLU   A CG    1 
ATOM   2215 C CD    . GLU   D 2 208 ? 255.093 211.516 220.167 1.00 68.68  ? 220 GLU   A CD    1 
ATOM   2216 O OE1   . GLU   D 2 208 ? 253.906 211.160 220.021 1.00 73.54  ? 220 GLU   A OE1   1 
ATOM   2217 O OE2   . GLU   D 2 208 ? 255.721 212.161 219.304 1.00 73.91  ? 220 GLU   A OE2   1 
ATOM   2218 N N     . ARG   D 2 209 ? 254.963 207.421 223.997 1.00 53.57  ? 221 ARG   A N     1 
ATOM   2219 C CA    . ARG   D 2 209 ? 254.296 206.167 224.338 1.00 50.10  ? 221 ARG   A CA    1 
ATOM   2220 C C     . ARG   D 2 209 ? 253.670 206.231 225.726 1.00 49.21  ? 221 ARG   A C     1 
ATOM   2221 O O     . ARG   D 2 209 ? 252.543 205.760 225.937 1.00 49.09  ? 221 ARG   A O     1 
ATOM   2222 C CB    . ARG   D 2 209 ? 255.293 205.013 224.244 1.00 53.25  ? 221 ARG   A CB    1 
ATOM   2223 C CG    . ARG   D 2 209 ? 254.710 203.652 224.561 1.00 63.35  ? 221 ARG   A CG    1 
ATOM   2224 C CD    . ARG   D 2 209 ? 255.599 202.896 225.528 1.00 61.90  ? 221 ARG   A CD    1 
ATOM   2225 N NE    . ARG   D 2 209 ? 257.002 202.970 225.145 1.00 62.48  ? 221 ARG   A NE    1 
ATOM   2226 C CZ    . ARG   D 2 209 ? 258.013 202.932 226.001 1.00 74.31  ? 221 ARG   A CZ    1 
ATOM   2227 N NH1   . ARG   D 2 209 ? 257.812 202.828 227.304 1.00 71.04  ? 221 ARG   A NH1   1 
ATOM   2228 N NH2   . ARG   D 2 209 ? 259.258 203.001 225.539 1.00 74.42  ? 221 ARG   A NH2   1 
ATOM   2229 N N     . MET   D 2 210 ? 254.388 206.816 226.685 1.00 49.73  ? 222 MET   A N     1 
ATOM   2230 C CA    . MET   D 2 210 ? 253.866 206.935 228.040 1.00 51.78  ? 222 MET   A CA    1 
ATOM   2231 C C     . MET   D 2 210 ? 252.670 207.875 228.083 1.00 51.54  ? 222 MET   A C     1 
ATOM   2232 O O     . MET   D 2 210 ? 251.683 207.604 228.778 1.00 52.88  ? 222 MET   A O     1 
ATOM   2233 C CB    . MET   D 2 210 ? 254.977 207.408 228.972 1.00 51.73  ? 222 MET   A CB    1 
ATOM   2234 C CG    . MET   D 2 210 ? 256.046 206.357 229.191 1.00 56.53  ? 222 MET   A CG    1 
ATOM   2235 S SD    . MET   D 2 210 ? 257.516 207.000 229.999 1.00 65.87  ? 222 MET   A SD    1 
ATOM   2236 C CE    . MET   D 2 210 ? 256.964 206.990 231.689 1.00 61.13  ? 222 MET   A CE    1 
ATOM   2237 N N     . CYS   D 2 211 ? 252.727 208.973 227.327 1.00 51.51  ? 223 CYS   A N     1 
ATOM   2238 C CA    . CYS   D 2 211 ? 251.578 209.864 227.239 1.00 52.63  ? 223 CYS   A CA    1 
ATOM   2239 C C     . CYS   D 2 211 ? 250.386 209.161 226.604 1.00 50.76  ? 223 CYS   A C     1 
ATOM   2240 O O     . CYS   D 2 211 ? 249.242 209.376 227.012 1.00 49.10  ? 223 CYS   A O     1 
ATOM   2241 C CB    . CYS   D 2 211 ? 251.948 211.118 226.450 1.00 53.03  ? 223 CYS   A CB    1 
ATOM   2242 S SG    . CYS   D 2 211 ? 252.663 212.435 227.450 1.00 67.81  ? 223 CYS   A SG    1 
ATOM   2243 N N     . ASN   D 2 212 ? 250.633 208.313 225.605 1.00 50.56  ? 224 ASN   A N     1 
ATOM   2244 C CA    . ASN   D 2 212 ? 249.533 207.622 224.942 1.00 48.71  ? 224 ASN   A CA    1 
ATOM   2245 C C     . ASN   D 2 212 ? 248.866 206.614 225.870 1.00 48.96  ? 224 ASN   A C     1 
ATOM   2246 O O     . ASN   D 2 212 ? 247.634 206.506 225.899 1.00 50.03  ? 224 ASN   A O     1 
ATOM   2247 C CB    . ASN   D 2 212 ? 250.036 206.941 223.672 1.00 49.64  ? 224 ASN   A CB    1 
ATOM   2248 C CG    . ASN   D 2 212 ? 249.983 207.852 222.464 1.00 49.13  ? 224 ASN   A CG    1 
ATOM   2249 O OD1   . ASN   D 2 212 ? 249.165 208.768 222.399 1.00 50.13  ? 224 ASN   A OD1   1 
ATOM   2250 N ND2   . ASN   D 2 212 ? 250.863 207.610 221.503 1.00 49.94  ? 224 ASN   A ND2   1 
ATOM   2251 N N     . ILE   D 2 213 ? 249.655 205.865 226.642 1.00 48.91  ? 225 ILE   A N     1 
ATOM   2252 C CA    . ILE   D 2 213 ? 249.025 204.918 227.560 1.00 53.08  ? 225 ILE   A CA    1 
ATOM   2253 C C     . ILE   D 2 213 ? 248.349 205.646 228.721 1.00 51.27  ? 225 ILE   A C     1 
ATOM   2254 O O     . ILE   D 2 213 ? 247.309 205.194 229.222 1.00 50.25  ? 225 ILE   A O     1 
ATOM   2255 C CB    . ILE   D 2 213 ? 250.029 203.850 228.033 1.00 53.35  ? 225 ILE   A CB    1 
ATOM   2256 C CG1   . ILE   D 2 213 ? 251.231 204.482 228.711 1.00 47.33  ? 225 ILE   A CG1   1 
ATOM   2257 C CG2   . ILE   D 2 213 ? 250.472 202.984 226.862 1.00 58.32  ? 225 ILE   A CG2   1 
ATOM   2258 C CD1   . ILE   D 2 213 ? 252.392 203.536 228.883 1.00 48.66  ? 225 ILE   A CD1   1 
ATOM   2259 N N     . LEU   D 2 214 ? 248.891 206.790 229.149 1.00 50.38  ? 226 LEU   A N     1 
ATOM   2260 C CA    . LEU   D 2 214 ? 248.181 207.605 230.132 1.00 47.99  ? 226 LEU   A CA    1 
ATOM   2261 C C     . LEU   D 2 214 ? 246.857 208.114 229.575 1.00 47.00  ? 226 LEU   A C     1 
ATOM   2262 O O     . LEU   D 2 214 ? 245.843 208.138 230.281 1.00 48.32  ? 226 LEU   A O     1 
ATOM   2263 C CB    . LEU   D 2 214 ? 249.054 208.774 230.585 1.00 48.40  ? 226 LEU   A CB    1 
ATOM   2264 C CG    . LEU   D 2 214 ? 248.384 209.752 231.554 1.00 49.21  ? 226 LEU   A CG    1 
ATOM   2265 C CD1   . LEU   D 2 214 ? 247.997 209.042 232.835 1.00 53.65  ? 226 LEU   A CD1   1 
ATOM   2266 C CD2   . LEU   D 2 214 ? 249.290 210.930 231.852 1.00 47.37  ? 226 LEU   A CD2   1 
ATOM   2267 N N     . LYS   D 2 215 ? 246.850 208.533 228.308 1.00 47.72  ? 227 LYS   A N     1 
ATOM   2268 C CA    . LYS   D 2 215 ? 245.617 208.976 227.668 1.00 49.85  ? 227 LYS   A CA    1 
ATOM   2269 C C     . LYS   D 2 215 ? 244.603 207.845 227.603 1.00 50.83  ? 227 LYS   A C     1 
ATOM   2270 O O     . LYS   D 2 215 ? 243.408 208.055 227.842 1.00 51.71  ? 227 LYS   A O     1 
ATOM   2271 C CB    . LYS   D 2 215 ? 245.928 209.504 226.269 1.00 50.46  ? 227 LYS   A CB    1 
ATOM   2272 C CG    . LYS   D 2 215 ? 244.730 210.001 225.491 1.00 49.02  ? 227 LYS   A CG    1 
ATOM   2273 C CD    . LYS   D 2 215 ? 245.147 210.432 224.097 1.00 50.39  ? 227 LYS   A CD    1 
ATOM   2274 C CE    . LYS   D 2 215 ? 243.958 210.847 223.257 1.00 54.63  ? 227 LYS   A CE    1 
ATOM   2275 N NZ    . LYS   D 2 215 ? 244.332 211.000 221.829 1.00 54.31  ? 227 LYS   A NZ    1 
ATOM   2276 N N     . GLY   D 2 216 ? 245.064 206.638 227.280 1.00 52.94  ? 228 GLY   A N     1 
ATOM   2277 C CA    . GLY   D 2 216 ? 244.187 205.483 227.334 1.00 51.76  ? 228 GLY   A CA    1 
ATOM   2278 C C     . GLY   D 2 216 ? 243.645 205.224 228.724 1.00 47.56  ? 228 GLY   A C     1 
ATOM   2279 O O     . GLY   D 2 216 ? 242.531 204.719 228.877 1.00 47.45  ? 228 GLY   A O     1 
ATOM   2280 N N     . LYS   D 2 217 ? 244.421 205.567 229.754 1.00 50.48  ? 229 LYS   A N     1 
ATOM   2281 C CA    . LYS   D 2 217 ? 243.945 205.395 231.124 1.00 49.26  ? 229 LYS   A CA    1 
ATOM   2282 C C     . LYS   D 2 217 ? 242.737 206.284 231.415 1.00 51.68  ? 229 LYS   A C     1 
ATOM   2283 O O     . LYS   D 2 217 ? 241.795 205.858 232.091 1.00 54.93  ? 229 LYS   A O     1 
ATOM   2284 C CB    . LYS   D 2 217 ? 245.080 205.685 232.106 1.00 45.97  ? 229 LYS   A CB    1 
ATOM   2285 C CG    . LYS   D 2 217 ? 245.176 204.701 233.251 1.00 50.17  ? 229 LYS   A CG    1 
ATOM   2286 C CD    . LYS   D 2 217 ? 246.602 204.570 233.757 1.00 50.97  ? 229 LYS   A CD    1 
ATOM   2287 C CE    . LYS   D 2 217 ? 247.407 203.598 232.916 1.00 44.44  ? 229 LYS   A CE    1 
ATOM   2288 N NZ    . LYS   D 2 217 ? 246.870 202.219 233.000 1.00 40.62  ? 229 LYS   A NZ    1 
ATOM   2289 N N     . PHE   D 2 218 ? 242.744 207.516 230.915 1.00 51.54  ? 230 PHE   A N     1 
ATOM   2290 C CA    . PHE   D 2 218 ? 241.680 208.462 231.221 1.00 50.02  ? 230 PHE   A CA    1 
ATOM   2291 C C     . PHE   D 2 218 ? 240.389 208.097 230.490 1.00 53.87  ? 230 PHE   A C     1 
ATOM   2292 O O     . PHE   D 2 218 ? 240.391 207.385 229.483 1.00 59.51  ? 230 PHE   A O     1 
ATOM   2293 C CB    . PHE   D 2 218 ? 242.106 209.883 230.853 1.00 48.87  ? 230 PHE   A CB    1 
ATOM   2294 C CG    . PHE   D 2 218 ? 242.941 210.556 231.902 1.00 47.82  ? 230 PHE   A CG    1 
ATOM   2295 C CD1   . PHE   D 2 218 ? 242.582 210.495 233.235 1.00 50.43  ? 230 PHE   A CD1   1 
ATOM   2296 C CD2   . PHE   D 2 218 ? 244.083 211.254 231.554 1.00 48.04  ? 230 PHE   A CD2   1 
ATOM   2297 C CE1   . PHE   D 2 218 ? 243.347 211.116 234.200 1.00 52.10  ? 230 PHE   A CE1   1 
ATOM   2298 C CE2   . PHE   D 2 218 ? 244.852 211.876 232.517 1.00 46.65  ? 230 PHE   A CE2   1 
ATOM   2299 C CZ    . PHE   D 2 218 ? 244.483 211.807 233.841 1.00 46.05  ? 230 PHE   A CZ    1 
ATOM   2300 N N     . GLN   D 2 219 ? 239.274 208.606 231.011 1.00 51.86  ? 231 GLN   A N     1 
ATOM   2301 C CA    . GLN   D 2 219 ? 237.945 208.281 230.507 1.00 51.28  ? 231 GLN   A CA    1 
ATOM   2302 C C     . GLN   D 2 219 ? 237.250 209.458 229.839 1.00 54.37  ? 231 GLN   A C     1 
ATOM   2303 O O     . GLN   D 2 219 ? 236.774 209.330 228.708 1.00 60.71  ? 231 GLN   A O     1 
ATOM   2304 C CB    . GLN   D 2 219 ? 237.067 207.748 231.648 1.00 51.60  ? 231 GLN   A CB    1 
ATOM   2305 C CG    . GLN   D 2 219 ? 237.000 206.237 231.729 1.00 51.95  ? 231 GLN   A CG    1 
ATOM   2306 C CD    . GLN   D 2 219 ? 236.372 205.753 233.020 1.00 58.38  ? 231 GLN   A CD    1 
ATOM   2307 O OE1   . GLN   D 2 219 ? 236.621 206.305 234.088 1.00 57.47  ? 231 GLN   A OE1   1 
ATOM   2308 N NE2   . GLN   D 2 219 ? 235.557 204.713 232.926 1.00 61.19  ? 231 GLN   A NE2   1 
ATOM   2309 N N     . THR   D 2 220 ? 237.169 210.604 230.508 1.00 51.27  ? 232 THR   A N     1 
ATOM   2310 C CA    . THR   D 2 220 ? 236.477 211.749 229.937 1.00 50.88  ? 232 THR   A CA    1 
ATOM   2311 C C     . THR   D 2 220 ? 237.265 212.329 228.767 1.00 54.23  ? 232 THR   A C     1 
ATOM   2312 O O     . THR   D 2 220 ? 238.485 212.181 228.666 1.00 57.46  ? 232 THR   A O     1 
ATOM   2313 C CB    . THR   D 2 220 ? 236.247 212.829 230.993 1.00 51.35  ? 232 THR   A CB    1 
ATOM   2314 O OG1   . THR   D 2 220 ? 237.397 213.678 231.066 1.00 59.51  ? 232 THR   A OG1   1 
ATOM   2315 C CG2   . THR   D 2 220 ? 236.004 212.201 232.347 1.00 52.99  ? 232 THR   A CG2   1 
ATOM   2316 N N     . ALA   D 2 221 ? 236.541 212.999 227.869 1.00 51.17  ? 233 ALA   A N     1 
ATOM   2317 C CA    . ALA   D 2 221 ? 237.169 213.559 226.678 1.00 46.82  ? 233 ALA   A CA    1 
ATOM   2318 C C     . ALA   D 2 221 ? 238.090 214.724 227.014 1.00 52.10  ? 233 ALA   A C     1 
ATOM   2319 O O     . ALA   D 2 221 ? 239.112 214.913 226.346 1.00 53.65  ? 233 ALA   A O     1 
ATOM   2320 C CB    . ALA   D 2 221 ? 236.102 214.001 225.679 1.00 40.18  ? 233 ALA   A CB    1 
ATOM   2321 N N     . ALA   D 2 222 ? 237.745 215.517 228.029 1.00 51.41  ? 234 ALA   A N     1 
ATOM   2322 C CA    . ALA   D 2 222 ? 238.561 216.677 228.375 1.00 48.38  ? 234 ALA   A CA    1 
ATOM   2323 C C     . ALA   D 2 222 ? 239.935 216.262 228.889 1.00 49.98  ? 234 ALA   A C     1 
ATOM   2324 O O     . ALA   D 2 222 ? 240.949 216.877 228.536 1.00 52.06  ? 234 ALA   A O     1 
ATOM   2325 C CB    . ALA   D 2 222 ? 237.834 217.535 229.407 1.00 46.55  ? 234 ALA   A CB    1 
ATOM   2326 N N     . GLN   D 2 223 ? 239.988 215.224 229.724 1.00 48.21  ? 235 GLN   A N     1 
ATOM   2327 C CA    . GLN   D 2 223 ? 241.271 214.738 230.221 1.00 47.90  ? 235 GLN   A CA    1 
ATOM   2328 C C     . GLN   D 2 223 ? 242.132 214.206 229.082 1.00 49.36  ? 235 GLN   A C     1 
ATOM   2329 O O     . GLN   D 2 223 ? 243.346 214.451 229.039 1.00 51.14  ? 235 GLN   A O     1 
ATOM   2330 C CB    . GLN   D 2 223 ? 241.039 213.657 231.275 1.00 47.40  ? 235 GLN   A CB    1 
ATOM   2331 C CG    . GLN   D 2 223 ? 240.568 214.192 232.614 1.00 44.33  ? 235 GLN   A CG    1 
ATOM   2332 C CD    . GLN   D 2 223 ? 240.008 213.109 233.512 1.00 44.59  ? 235 GLN   A CD    1 
ATOM   2333 O OE1   . GLN   D 2 223 ? 239.203 212.287 233.083 1.00 49.94  ? 235 GLN   A OE1   1 
ATOM   2334 N NE2   . GLN   D 2 223 ? 240.435 213.103 234.767 1.00 43.93  ? 235 GLN   A NE2   1 
ATOM   2335 N N     . ARG   D 2 224 ? 241.518 213.476 228.150 1.00 47.48  ? 236 ARG   A N     1 
ATOM   2336 C CA    . ARG   D 2 224 ? 242.252 212.967 226.998 1.00 49.50  ? 236 ARG   A CA    1 
ATOM   2337 C C     . ARG   D 2 224 ? 242.777 214.105 226.135 1.00 50.66  ? 236 ARG   A C     1 
ATOM   2338 O O     . ARG   D 2 224 ? 243.912 214.055 225.652 1.00 54.66  ? 236 ARG   A O     1 
ATOM   2339 C CB    . ARG   D 2 224 ? 241.358 212.037 226.183 1.00 51.93  ? 236 ARG   A CB    1 
ATOM   2340 C CG    . ARG   D 2 224 ? 240.989 210.759 226.905 1.00 50.18  ? 236 ARG   A CG    1 
ATOM   2341 C CD    . ARG   D 2 224 ? 239.719 210.166 226.331 1.00 51.51  ? 236 ARG   A CD    1 
ATOM   2342 N NE    . ARG   D 2 224 ? 240.001 209.026 225.471 1.00 51.43  ? 236 ARG   A NE    1 
ATOM   2343 C CZ    . ARG   D 2 224 ? 240.136 207.781 225.902 1.00 56.89  ? 236 ARG   A CZ    1 
ATOM   2344 N NH1   . ARG   D 2 224 ? 240.001 207.475 227.181 1.00 59.74  ? 236 ARG   A NH1   1 
ATOM   2345 N NH2   . ARG   D 2 224 ? 240.414 206.819 225.028 1.00 61.50  ? 236 ARG   A NH2   1 
ATOM   2346 N N     . THR   D 2 225 ? 241.970 215.149 225.940 1.00 49.76  ? 237 THR   A N     1 
ATOM   2347 C CA    . THR   D 2 225 ? 242.423 216.298 225.165 1.00 49.83  ? 237 THR   A CA    1 
ATOM   2348 C C     . THR   D 2 225 ? 243.587 217.000 225.853 1.00 49.04  ? 237 THR   A C     1 
ATOM   2349 O O     . THR   D 2 225 ? 244.544 217.426 225.196 1.00 50.68  ? 237 THR   A O     1 
ATOM   2350 C CB    . THR   D 2 225 ? 241.263 217.266 224.935 1.00 50.11  ? 237 THR   A CB    1 
ATOM   2351 O OG1   . THR   D 2 225 ? 240.370 216.716 223.961 1.00 51.78  ? 237 THR   A OG1   1 
ATOM   2352 C CG2   . THR   D 2 225 ? 241.771 218.602 224.428 1.00 52.62  ? 237 THR   A CG2   1 
ATOM   2353 N N     . MET   D 2 226 ? 243.533 217.120 227.181 1.00 49.48  ? 238 MET   A N     1 
ATOM   2354 C CA    . MET   D 2 226 ? 244.614 217.802 227.886 1.00 50.08  ? 238 MET   A CA    1 
ATOM   2355 C C     . MET   D 2 226 ? 245.910 216.999 227.837 1.00 51.28  ? 238 MET   A C     1 
ATOM   2356 O O     . MET   D 2 226 ? 246.992 217.570 227.650 1.00 53.05  ? 238 MET   A O     1 
ATOM   2357 C CB    . MET   D 2 226 ? 244.218 218.088 229.331 1.00 47.19  ? 238 MET   A CB    1 
ATOM   2358 C CG    . MET   D 2 226 ? 244.953 219.284 229.893 1.00 45.95  ? 238 MET   A CG    1 
ATOM   2359 S SD    . MET   D 2 226 ? 244.169 220.040 231.318 1.00 55.16  ? 238 MET   A SD    1 
ATOM   2360 C CE    . MET   D 2 226 ? 245.542 219.999 232.456 1.00 51.35  ? 238 MET   A CE    1 
ATOM   2361 N N     . VAL   D 2 227 ? 245.830 215.677 228.000 1.00 49.36  ? 239 VAL   A N     1 
ATOM   2362 C CA    . VAL   D 2 227 ? 247.055 214.888 227.895 1.00 49.00  ? 239 VAL   A CA    1 
ATOM   2363 C C     . VAL   D 2 227 ? 247.562 214.882 226.455 1.00 50.02  ? 239 VAL   A C     1 
ATOM   2364 O O     . VAL   D 2 227 ? 248.775 214.826 226.217 1.00 53.11  ? 239 VAL   A O     1 
ATOM   2365 C CB    . VAL   D 2 227 ? 246.850 213.464 228.451 1.00 48.20  ? 239 VAL   A CB    1 
ATOM   2366 C CG1   . VAL   D 2 227 ? 245.750 212.749 227.722 1.00 51.55  ? 239 VAL   A CG1   1 
ATOM   2367 C CG2   . VAL   D 2 227 ? 248.143 212.670 228.379 1.00 51.93  ? 239 VAL   A CG2   1 
ATOM   2368 N N     . ASP   D 2 228 ? 246.658 214.966 225.475 1.00 49.46  ? 240 ASP   A N     1 
ATOM   2369 C CA    . ASP   D 2 228 ? 247.082 215.126 224.089 1.00 50.69  ? 240 ASP   A CA    1 
ATOM   2370 C C     . ASP   D 2 228 ? 247.858 216.423 223.902 1.00 50.15  ? 240 ASP   A C     1 
ATOM   2371 O O     . ASP   D 2 228 ? 248.894 216.447 223.227 1.00 52.06  ? 240 ASP   A O     1 
ATOM   2372 C CB    . ASP   D 2 228 ? 245.863 215.100 223.168 1.00 53.65  ? 240 ASP   A CB    1 
ATOM   2373 C CG    . ASP   D 2 228 ? 246.010 214.119 222.032 1.00 61.81  ? 240 ASP   A CG    1 
ATOM   2374 O OD1   . ASP   D 2 228 ? 247.087 213.502 221.915 1.00 68.70  ? 240 ASP   A OD1   1 
ATOM   2375 O OD2   . ASP   D 2 228 ? 245.046 213.967 221.254 1.00 63.49  ? 240 ASP   A OD2   1 
ATOM   2376 N N     . GLN   D 2 229 ? 247.367 217.512 224.493 1.00 51.70  ? 241 GLN   A N     1 
ATOM   2377 C CA    . GLN   D 2 229 ? 248.063 218.791 224.398 1.00 52.96  ? 241 GLN   A CA    1 
ATOM   2378 C C     . GLN   D 2 229 ? 249.422 218.731 225.085 1.00 52.56  ? 241 GLN   A C     1 
ATOM   2379 O O     . GLN   D 2 229 ? 250.387 219.350 224.624 1.00 51.43  ? 241 GLN   A O     1 
ATOM   2380 C CB    . GLN   D 2 229 ? 247.202 219.901 225.000 1.00 50.43  ? 241 GLN   A CB    1 
ATOM   2381 C CG    . GLN   D 2 229 ? 246.077 220.364 224.099 1.00 52.71  ? 241 GLN   A CG    1 
ATOM   2382 C CD    . GLN   D 2 229 ? 245.165 221.364 224.775 1.00 61.23  ? 241 GLN   A CD    1 
ATOM   2383 O OE1   . GLN   D 2 229 ? 245.473 221.878 225.849 1.00 61.97  ? 241 GLN   A OE1   1 
ATOM   2384 N NE2   . GLN   D 2 229 ? 244.035 221.650 224.144 1.00 66.02  ? 241 GLN   A NE2   1 
ATOM   2385 N N     . VAL   D 2 230 ? 249.509 218.001 226.198 1.00 53.49  ? 242 VAL   A N     1 
ATOM   2386 C CA    . VAL   D 2 230 ? 250.796 217.805 226.862 1.00 50.40  ? 242 VAL   A CA    1 
ATOM   2387 C C     . VAL   D 2 230 ? 251.752 217.040 225.956 1.00 52.60  ? 242 VAL   A C     1 
ATOM   2388 O O     . VAL   D 2 230 ? 252.948 217.348 225.885 1.00 55.60  ? 242 VAL   A O     1 
ATOM   2389 C CB    . VAL   D 2 230 ? 250.596 217.089 228.211 1.00 47.67  ? 242 VAL   A CB    1 
ATOM   2390 C CG1   . VAL   D 2 230 ? 251.930 216.692 228.808 1.00 46.34  ? 242 VAL   A CG1   1 
ATOM   2391 C CG2   . VAL   D 2 230 ? 249.838 217.982 229.171 1.00 50.55  ? 242 VAL   A CG2   1 
ATOM   2392 N N     . ARG   D 2 231 ? 251.241 216.033 225.247 1.00 52.78  ? 243 ARG   A N     1 
ATOM   2393 C CA    . ARG   D 2 231 ? 252.087 215.221 224.380 1.00 52.59  ? 243 ARG   A CA    1 
ATOM   2394 C C     . ARG   D 2 231 ? 252.635 216.016 223.198 1.00 56.77  ? 243 ARG   A C     1 
ATOM   2395 O O     . ARG   D 2 231 ? 253.749 215.747 222.737 1.00 63.05  ? 243 ARG   A O     1 
ATOM   2396 C CB    . ARG   D 2 231 ? 251.300 214.006 223.887 1.00 52.39  ? 243 ARG   A CB    1 
ATOM   2397 C CG    . ARG   D 2 231 ? 252.006 213.186 222.832 1.00 52.93  ? 243 ARG   A CG    1 
ATOM   2398 C CD    . ARG   D 2 231 ? 251.313 211.856 222.608 1.00 57.95  ? 243 ARG   A CD    1 
ATOM   2399 N NE    . ARG   D 2 231 ? 250.000 212.000 221.990 1.00 55.28  ? 243 ARG   A NE    1 
ATOM   2400 C CZ    . ARG   D 2 231 ? 249.792 212.417 220.749 1.00 57.79  ? 243 ARG   A CZ    1 
ATOM   2401 N NH1   . ARG   D 2 231 ? 250.793 212.760 219.955 1.00 57.79  ? 243 ARG   A NH1   1 
ATOM   2402 N NH2   . ARG   D 2 231 ? 248.547 212.489 220.290 1.00 61.00  ? 243 ARG   A NH2   1 
ATOM   2403 N N     . GLU   D 2 232 ? 251.888 217.004 222.709 1.00 55.35  ? 244 GLU   A N     1 
ATOM   2404 C CA    . GLU   D 2 232 ? 252.240 217.692 221.473 1.00 51.78  ? 244 GLU   A CA    1 
ATOM   2405 C C     . GLU   D 2 232 ? 253.378 218.695 221.626 1.00 55.90  ? 244 GLU   A C     1 
ATOM   2406 O O     . GLU   D 2 232 ? 253.835 219.235 220.614 1.00 62.90  ? 244 GLU   A O     1 
ATOM   2407 C CB    . GLU   D 2 232 ? 251.014 218.412 220.907 1.00 54.24  ? 244 GLU   A CB    1 
ATOM   2408 C CG    . GLU   D 2 232 ? 249.935 217.496 220.344 1.00 59.30  ? 244 GLU   A CG    1 
ATOM   2409 C CD    . GLU   D 2 232 ? 250.485 216.416 219.437 1.00 64.18  ? 244 GLU   A CD    1 
ATOM   2410 O OE1   . GLU   D 2 232 ? 251.260 216.746 218.517 1.00 71.65  ? 244 GLU   A OE1   1 
ATOM   2411 O OE2   . GLU   D 2 232 ? 250.130 215.237 219.635 1.00 62.78  ? 244 GLU   A OE2   1 
ATOM   2412 N N     . SER   D 2 233 ? 253.841 218.966 222.842 1.00 53.09  ? 245 SER   A N     1 
ATOM   2413 C CA    . SER   D 2 233 ? 254.885 219.961 223.049 1.00 55.67  ? 245 SER   A CA    1 
ATOM   2414 C C     . SER   D 2 233 ? 256.250 219.401 222.667 1.00 58.21  ? 245 SER   A C     1 
ATOM   2415 O O     . SER   D 2 233 ? 256.621 218.302 223.088 1.00 60.29  ? 245 SER   A O     1 
ATOM   2416 C CB    . SER   D 2 233 ? 254.895 220.422 224.503 1.00 59.54  ? 245 SER   A CB    1 
ATOM   2417 O OG    . SER   D 2 233 ? 255.586 219.493 225.315 1.00 64.40  ? 245 SER   A OG    1 
ATOM   2418 N N     . ARG   D 2 234 ? 257.001 220.163 221.869 1.00 60.13  ? 246 ARG   A N     1 
ATOM   2419 C CA    . ARG   D 2 234 ? 258.321 219.712 221.441 1.00 61.08  ? 246 ARG   A CA    1 
ATOM   2420 C C     . ARG   D 2 234 ? 259.308 219.722 222.602 1.00 61.93  ? 246 ARG   A C     1 
ATOM   2421 O O     . ARG   D 2 234 ? 260.056 218.760 222.803 1.00 59.33  ? 246 ARG   A O     1 
ATOM   2422 C CB    . ARG   D 2 234 ? 258.834 220.586 220.296 1.00 68.49  ? 246 ARG   A CB    1 
ATOM   2423 C CG    . ARG   D 2 234 ? 257.991 220.525 219.028 1.00 76.55  ? 246 ARG   A CG    1 
ATOM   2424 C CD    . ARG   D 2 234 ? 258.046 219.141 218.390 1.00 69.65  ? 246 ARG   A CD    1 
ATOM   2425 N NE    . ARG   D 2 234 ? 257.263 219.071 217.162 1.00 63.40  ? 246 ARG   A NE    1 
ATOM   2426 C CZ    . ARG   D 2 234 ? 256.952 217.946 216.533 1.00 59.05  ? 246 ARG   A CZ    1 
ATOM   2427 N NH1   . ARG   D 2 234 ? 257.347 216.768 216.986 1.00 52.65  ? 246 ARG   A NH1   1 
ATOM   2428 N NH2   . ARG   D 2 234 ? 256.230 218.004 215.419 1.00 52.76  ? 246 ARG   A NH2   1 
ATOM   2429 N N     . ASN   D 2 235 ? 259.324 220.804 223.380 1.00 59.86  ? 247 ASN   A N     1 
ATOM   2430 C CA    . ASN   D 2 235 ? 260.172 220.917 224.566 1.00 59.76  ? 247 ASN   A CA    1 
ATOM   2431 C C     . ASN   D 2 235 ? 259.260 221.167 225.757 1.00 62.09  ? 247 ASN   A C     1 
ATOM   2432 O O     . ASN   D 2 235 ? 259.000 222.324 226.121 1.00 61.23  ? 247 ASN   A O     1 
ATOM   2433 C CB    . ASN   D 2 235 ? 261.209 222.028 224.417 1.00 62.42  ? 247 ASN   A CB    1 
ATOM   2434 C CG    . ASN   D 2 235 ? 262.285 221.969 225.488 1.00 63.16  ? 247 ASN   A CG    1 
ATOM   2435 O OD1   . ASN   D 2 235 ? 262.754 220.892 225.850 1.00 64.94  ? 247 ASN   A OD1   1 
ATOM   2436 N ND2   . ASN   D 2 235 ? 262.686 223.128 225.992 1.00 57.01  ? 247 ASN   A ND2   1 
ATOM   2437 N N     . PRO   D 2 236 ? 258.740 220.114 226.381 1.00 62.21  ? 248 PRO   A N     1 
ATOM   2438 C CA    . PRO   D 2 236 ? 257.847 220.303 227.529 1.00 57.23  ? 248 PRO   A CA    1 
ATOM   2439 C C     . PRO   D 2 236 ? 258.584 220.932 228.700 1.00 54.78  ? 248 PRO   A C     1 
ATOM   2440 O O     . PRO   D 2 236 ? 259.652 220.470 229.106 1.00 54.83  ? 248 PRO   A O     1 
ATOM   2441 C CB    . PRO   D 2 236 ? 257.377 218.880 227.851 1.00 58.04  ? 248 PRO   A CB    1 
ATOM   2442 C CG    . PRO   D 2 236 ? 258.375 217.986 227.210 1.00 57.54  ? 248 PRO   A CG    1 
ATOM   2443 C CD    . PRO   D 2 236 ? 258.878 218.699 226.006 1.00 63.26  ? 248 PRO   A CD    1 
ATOM   2444 N N     . GLY   D 2 237 ? 258.000 221.994 229.242 1.00 50.28  ? 249 GLY   A N     1 
ATOM   2445 C CA    . GLY   D 2 237 ? 258.622 222.711 230.331 1.00 51.87  ? 249 GLY   A CA    1 
ATOM   2446 C C     . GLY   D 2 237 ? 257.777 222.744 231.584 1.00 53.93  ? 249 GLY   A C     1 
ATOM   2447 O O     . GLY   D 2 237 ? 257.129 221.754 231.935 1.00 52.91  ? 249 GLY   A O     1 
ATOM   2448 N N     . ASN   D 2 238 ? 257.777 223.888 232.267 1.00 52.99  ? 250 ASN   A N     1 
ATOM   2449 C CA    . ASN   D 2 238 ? 257.039 224.000 233.519 1.00 51.25  ? 250 ASN   A CA    1 
ATOM   2450 C C     . ASN   D 2 238 ? 255.536 223.906 233.290 1.00 53.68  ? 250 ASN   A C     1 
ATOM   2451 O O     . ASN   D 2 238 ? 254.812 223.349 234.124 1.00 55.83  ? 250 ASN   A O     1 
ATOM   2452 C CB    . ASN   D 2 238 ? 257.404 225.308 234.219 1.00 51.41  ? 250 ASN   A CB    1 
ATOM   2453 C CG    . ASN   D 2 238 ? 256.595 225.543 235.472 1.00 59.44  ? 250 ASN   A CG    1 
ATOM   2454 O OD1   . ASN   D 2 238 ? 255.467 226.027 235.416 1.00 64.08  ? 250 ASN   A OD1   1 
ATOM   2455 N ND2   . ASN   D 2 238 ? 257.168 225.198 236.616 1.00 63.33  ? 250 ASN   A ND2   1 
ATOM   2456 N N     . ALA   D 2 239 ? 255.049 224.444 232.169 1.00 49.42  ? 251 ALA   A N     1 
ATOM   2457 C CA    . ALA   D 2 239 ? 253.612 224.455 231.918 1.00 48.32  ? 251 ALA   A CA    1 
ATOM   2458 C C     . ALA   D 2 239 ? 253.054 223.043 231.807 1.00 46.19  ? 251 ALA   A C     1 
ATOM   2459 O O     . ALA   D 2 239 ? 251.990 222.745 232.358 1.00 47.82  ? 251 ALA   A O     1 
ATOM   2460 C CB    . ALA   D 2 239 ? 253.308 225.252 230.651 1.00 48.51  ? 251 ALA   A CB    1 
ATOM   2461 N N     . GLU   D 2 240 ? 253.761 222.158 231.104 1.00 47.19  ? 252 GLU   A N     1 
ATOM   2462 C CA    . GLU   D 2 240 ? 253.281 220.790 230.951 1.00 47.07  ? 252 GLU   A CA    1 
ATOM   2463 C C     . GLU   D 2 240 ? 253.369 220.014 232.258 1.00 49.32  ? 252 GLU   A C     1 
ATOM   2464 O O     . GLU   D 2 240 ? 252.513 219.170 232.533 1.00 51.34  ? 252 GLU   A O     1 
ATOM   2465 C CB    . GLU   D 2 240 ? 254.062 220.083 229.846 1.00 48.72  ? 252 GLU   A CB    1 
ATOM   2466 C CG    . GLU   D 2 240 ? 253.530 220.364 228.451 1.00 52.61  ? 252 GLU   A CG    1 
ATOM   2467 C CD    . GLU   D 2 240 ? 253.887 221.751 227.952 1.00 54.24  ? 252 GLU   A CD    1 
ATOM   2468 O OE1   . GLU   D 2 240 ? 254.784 222.384 228.544 1.00 60.30  ? 252 GLU   A OE1   1 
ATOM   2469 O OE2   . GLU   D 2 240 ? 253.267 222.211 226.973 1.00 45.60  ? 252 GLU   A OE2   1 
ATOM   2470 N N     . PHE   D 2 241 ? 254.381 220.295 233.078 1.00 49.95  ? 253 PHE   A N     1 
ATOM   2471 C CA    . PHE   D 2 241 ? 254.472 219.674 234.396 1.00 48.43  ? 253 PHE   A CA    1 
ATOM   2472 C C     . PHE   D 2 241 ? 253.316 220.114 235.293 1.00 47.25  ? 253 PHE   A C     1 
ATOM   2473 O O     . PHE   D 2 241 ? 252.717 219.291 236.000 1.00 48.85  ? 253 PHE   A O     1 
ATOM   2474 C CB    . PHE   D 2 241 ? 255.842 220.000 235.000 1.00 49.68  ? 253 PHE   A CB    1 
ATOM   2475 C CG    . PHE   D 2 241 ? 255.832 220.266 236.475 1.00 53.09  ? 253 PHE   A CG    1 
ATOM   2476 C CD1   . PHE   D 2 241 ? 255.853 219.225 237.381 1.00 53.99  ? 253 PHE   A CD1   1 
ATOM   2477 C CD2   . PHE   D 2 241 ? 255.846 221.562 236.956 1.00 57.24  ? 253 PHE   A CD2   1 
ATOM   2478 C CE1   . PHE   D 2 241 ? 255.863 219.472 238.735 1.00 54.07  ? 253 PHE   A CE1   1 
ATOM   2479 C CE2   . PHE   D 2 241 ? 255.853 221.812 238.310 1.00 53.65  ? 253 PHE   A CE2   1 
ATOM   2480 C CZ    . PHE   D 2 241 ? 255.861 220.767 239.199 1.00 50.48  ? 253 PHE   A CZ    1 
ATOM   2481 N N     . GLU   D 2 242 ? 252.959 221.399 235.243 1.00 45.80  ? 254 GLU   A N     1 
ATOM   2482 C CA    . GLU   D 2 242 ? 251.805 221.879 235.999 1.00 49.55  ? 254 GLU   A CA    1 
ATOM   2483 C C     . GLU   D 2 242 ? 250.502 221.284 235.473 1.00 48.25  ? 254 GLU   A C     1 
ATOM   2484 O O     . GLU   D 2 242 ? 249.604 220.955 236.255 1.00 46.27  ? 254 GLU   A O     1 
ATOM   2485 C CB    . GLU   D 2 242 ? 251.753 223.405 235.961 1.00 49.76  ? 254 GLU   A CB    1 
ATOM   2486 C CG    . GLU   D 2 242 ? 252.934 224.072 236.627 1.00 55.42  ? 254 GLU   A CG    1 
ATOM   2487 C CD    . GLU   D 2 242 ? 252.539 224.849 237.861 1.00 67.86  ? 254 GLU   A CD    1 
ATOM   2488 O OE1   . GLU   D 2 242 ? 251.509 225.552 237.815 1.00 73.51  ? 254 GLU   A OE1   1 
ATOM   2489 O OE2   . GLU   D 2 242 ? 253.256 224.757 238.878 1.00 70.87  ? 254 GLU   A OE2   1 
ATOM   2490 N N     . ASP   D 2 243 ? 250.375 221.150 234.151 1.00 49.40  ? 255 ASP   A N     1 
ATOM   2491 C CA    . ASP   D 2 243 ? 249.179 220.535 233.581 1.00 47.84  ? 255 ASP   A CA    1 
ATOM   2492 C C     . ASP   D 2 243 ? 249.074 219.069 233.981 1.00 46.00  ? 255 ASP   A C     1 
ATOM   2493 O O     . ASP   D 2 243 ? 247.974 218.560 234.223 1.00 47.73  ? 255 ASP   A O     1 
ATOM   2494 C CB    . ASP   D 2 243 ? 249.190 220.678 232.060 1.00 48.19  ? 255 ASP   A CB    1 
ATOM   2495 C CG    . ASP   D 2 243 ? 248.699 222.034 231.598 1.00 53.10  ? 255 ASP   A CG    1 
ATOM   2496 O OD1   . ASP   D 2 243 ? 248.792 223.000 232.380 1.00 58.58  ? 255 ASP   A OD1   1 
ATOM   2497 O OD2   . ASP   D 2 243 ? 248.221 222.135 230.451 1.00 55.97  ? 255 ASP   A OD2   1 
ATOM   2498 N N     . LEU   D 2 244 ? 250.209 218.373 234.043 1.00 46.30  ? 256 LEU   A N     1 
ATOM   2499 C CA    . LEU   D 2 244 ? 250.211 216.993 234.512 1.00 46.50  ? 256 LEU   A CA    1 
ATOM   2500 C C     . LEU   D 2 244 ? 249.776 216.905 235.967 1.00 47.54  ? 256 LEU   A C     1 
ATOM   2501 O O     . LEU   D 2 244 ? 249.023 216.000 236.344 1.00 48.02  ? 256 LEU   A O     1 
ATOM   2502 C CB    . LEU   D 2 244 ? 251.599 216.383 234.330 1.00 45.58  ? 256 LEU   A CB    1 
ATOM   2503 C CG    . LEU   D 2 244 ? 251.904 215.859 232.930 1.00 45.84  ? 256 LEU   A CG    1 
ATOM   2504 C CD1   . LEU   D 2 244 ? 253.349 215.421 232.833 1.00 45.62  ? 256 LEU   A CD1   1 
ATOM   2505 C CD2   . LEU   D 2 244 ? 250.971 214.717 232.586 1.00 46.90  ? 256 LEU   A CD2   1 
ATOM   2506 N N     . ILE   D 2 245 ? 250.245 217.834 236.802 1.00 49.20  ? 257 ILE   A N     1 
ATOM   2507 C CA    . ILE   D 2 245 ? 249.802 217.859 238.195 1.00 46.74  ? 257 ILE   A CA    1 
ATOM   2508 C C     . ILE   D 2 245 ? 248.299 218.104 238.270 1.00 46.08  ? 257 ILE   A C     1 
ATOM   2509 O O     . ILE   D 2 245 ? 247.589 217.491 239.080 1.00 46.95  ? 257 ILE   A O     1 
ATOM   2510 C CB    . ILE   D 2 245 ? 250.596 218.912 238.988 1.00 45.93  ? 257 ILE   A CB    1 
ATOM   2511 C CG1   . ILE   D 2 245 ? 251.972 218.365 239.354 1.00 45.24  ? 257 ILE   A CG1   1 
ATOM   2512 C CG2   . ILE   D 2 245 ? 249.844 219.329 240.240 1.00 51.53  ? 257 ILE   A CG2   1 
ATOM   2513 C CD1   . ILE   D 2 245 ? 252.750 219.271 240.257 1.00 51.51  ? 257 ILE   A CD1   1 
ATOM   2514 N N     . PHE   D 2 246 ? 247.793 219.002 237.424 1.00 46.29  ? 258 PHE   A N     1 
ATOM   2515 C CA    . PHE   D 2 246 ? 246.358 219.262 237.384 1.00 48.90  ? 258 PHE   A CA    1 
ATOM   2516 C C     . PHE   D 2 246 ? 245.582 218.008 237.000 1.00 47.92  ? 258 PHE   A C     1 
ATOM   2517 O O     . PHE   D 2 246 ? 244.539 217.709 237.589 1.00 47.33  ? 258 PHE   A O     1 
ATOM   2518 C CB    . PHE   D 2 246 ? 246.060 220.394 236.402 1.00 49.73  ? 258 PHE   A CB    1 
ATOM   2519 C CG    . PHE   D 2 246 ? 244.598 220.704 236.254 1.00 48.77  ? 258 PHE   A CG    1 
ATOM   2520 C CD1   . PHE   D 2 246 ? 243.818 220.030 235.333 1.00 46.49  ? 258 PHE   A CD1   1 
ATOM   2521 C CD2   . PHE   D 2 246 ? 244.009 221.687 237.024 1.00 48.77  ? 258 PHE   A CD2   1 
ATOM   2522 C CE1   . PHE   D 2 246 ? 242.485 220.316 235.196 1.00 49.94  ? 258 PHE   A CE1   1 
ATOM   2523 C CE2   . PHE   D 2 246 ? 242.673 221.979 236.888 1.00 51.82  ? 258 PHE   A CE2   1 
ATOM   2524 C CZ    . PHE   D 2 246 ? 241.910 221.291 235.975 1.00 54.11  ? 258 PHE   A CZ    1 
ATOM   2525 N N     . LEU   D 2 247 ? 246.071 217.273 236.000 1.00 46.87  ? 259 LEU   A N     1 
ATOM   2526 C CA    . LEU   D 2 247 ? 245.406 216.042 235.587 1.00 44.91  ? 259 LEU   A CA    1 
ATOM   2527 C C     . LEU   D 2 247 ? 245.440 215.000 236.697 1.00 45.88  ? 259 LEU   A C     1 
ATOM   2528 O O     . LEU   D 2 247 ? 244.462 214.274 236.912 1.00 45.99  ? 259 LEU   A O     1 
ATOM   2529 C CB    . LEU   D 2 247 ? 246.059 215.496 234.319 1.00 45.26  ? 259 LEU   A CB    1 
ATOM   2530 C CG    . LEU   D 2 247 ? 245.502 216.000 232.990 1.00 44.80  ? 259 LEU   A CG    1 
ATOM   2531 C CD1   . LEU   D 2 247 ? 246.059 215.183 231.843 1.00 47.60  ? 259 LEU   A CD1   1 
ATOM   2532 C CD2   . LEU   D 2 247 ? 243.987 215.958 232.997 1.00 48.53  ? 259 LEU   A CD2   1 
ATOM   2533 N N     . ALA   D 2 248 ? 246.563 214.910 237.410 1.00 47.35  ? 260 ALA   A N     1 
ATOM   2534 C CA    . ALA   D 2 248 ? 246.659 213.970 238.520 1.00 48.36  ? 260 ALA   A CA    1 
ATOM   2535 C C     . ALA   D 2 248 ? 245.652 214.304 239.611 1.00 49.42  ? 260 ALA   A C     1 
ATOM   2536 O O     . ALA   D 2 248 ? 245.000 213.409 240.160 1.00 47.43  ? 260 ALA   A O     1 
ATOM   2537 C CB    . ALA   D 2 248 ? 248.079 213.964 239.080 1.00 51.05  ? 260 ALA   A CB    1 
ATOM   2538 N N     . ARG   D 2 249 ? 245.506 215.589 239.936 1.00 51.46  ? 261 ARG   A N     1 
ATOM   2539 C CA    . ARG   D 2 249 ? 244.512 215.979 240.931 1.00 49.52  ? 261 ARG   A CA    1 
ATOM   2540 C C     . ARG   D 2 249 ? 243.094 215.728 240.427 1.00 47.78  ? 261 ARG   A C     1 
ATOM   2541 O O     . ARG   D 2 249 ? 242.221 215.309 241.195 1.00 50.19  ? 261 ARG   A O     1 
ATOM   2542 C CB    . ARG   D 2 249 ? 244.700 217.443 241.320 1.00 52.18  ? 261 ARG   A CB    1 
ATOM   2543 C CG    . ARG   D 2 249 ? 243.585 217.988 242.183 1.00 57.01  ? 261 ARG   A CG    1 
ATOM   2544 C CD    . ARG   D 2 249 ? 243.974 219.292 242.843 1.00 61.56  ? 261 ARG   A CD    1 
ATOM   2545 N NE    . ARG   D 2 249 ? 244.283 219.113 244.255 1.00 59.75  ? 261 ARG   A NE    1 
ATOM   2546 C CZ    . ARG   D 2 249 ? 245.503 219.185 244.764 1.00 65.81  ? 261 ARG   A CZ    1 
ATOM   2547 N NH1   . ARG   D 2 249 ? 246.555 219.440 244.003 1.00 59.39  ? 261 ARG   A NH1   1 
ATOM   2548 N NH2   . ARG   D 2 249 ? 245.672 219.000 246.070 1.00 70.76  ? 261 ARG   A NH2   1 
ATOM   2549 N N     . SER   D 2 250 ? 242.848 215.969 239.137 1.00 47.29  ? 262 SER   A N     1 
ATOM   2550 C CA    . SER   D 2 250 ? 241.532 215.698 238.566 1.00 48.40  ? 262 SER   A CA    1 
ATOM   2551 C C     . SER   D 2 250 ? 241.201 214.213 238.590 1.00 47.82  ? 262 SER   A C     1 
ATOM   2552 O O     . SER   D 2 250 ? 240.024 213.843 238.665 1.00 46.22  ? 262 SER   A O     1 
ATOM   2553 C CB    . SER   D 2 250 ? 241.461 216.223 237.135 1.00 50.10  ? 262 SER   A CB    1 
ATOM   2554 O OG    . SER   D 2 250 ? 241.997 215.280 236.226 1.00 53.02  ? 262 SER   A OG    1 
ATOM   2555 N N     . ALA   D 2 251 ? 242.218 213.354 238.526 1.00 48.53  ? 263 ALA   A N     1 
ATOM   2556 C CA    . ALA   D 2 251 ? 241.996 211.914 238.573 1.00 46.00  ? 263 ALA   A CA    1 
ATOM   2557 C C     . ALA   D 2 251 ? 241.441 211.442 239.910 1.00 46.95  ? 263 ALA   A C     1 
ATOM   2558 O O     . ALA   D 2 251 ? 241.000 210.292 240.003 1.00 47.81  ? 263 ALA   A O     1 
ATOM   2559 C CB    . ALA   D 2 251 ? 243.296 211.172 238.269 1.00 47.63  ? 263 ALA   A CB    1 
ATOM   2560 N N     . LEU   D 2 252 ? 241.462 212.286 240.943 1.00 47.61  ? 264 LEU   A N     1 
ATOM   2561 C CA    . LEU   D 2 252 ? 240.898 211.895 242.229 1.00 47.26  ? 264 LEU   A CA    1 
ATOM   2562 C C     . LEU   D 2 252 ? 239.378 211.812 242.181 1.00 49.05  ? 264 LEU   A C     1 
ATOM   2563 O O     . LEU   D 2 252 ? 238.786 210.974 242.870 1.00 51.77  ? 264 LEU   A O     1 
ATOM   2564 C CB    . LEU   D 2 252 ? 241.342 212.872 243.316 1.00 45.71  ? 264 LEU   A CB    1 
ATOM   2565 C CG    . LEU   D 2 252 ? 242.820 212.844 243.703 1.00 44.49  ? 264 LEU   A CG    1 
ATOM   2566 C CD1   . LEU   D 2 252 ? 243.200 214.109 244.444 1.00 48.40  ? 264 LEU   A CD1   1 
ATOM   2567 C CD2   . LEU   D 2 252 ? 243.122 211.623 244.544 1.00 42.96  ? 264 LEU   A CD2   1 
ATOM   2568 N N     . ILE   D 2 253 ? 238.731 212.661 241.391 1.00 47.60  ? 265 ILE   A N     1 
ATOM   2569 C CA    . ILE   D 2 253 ? 237.277 212.659 241.261 1.00 46.88  ? 265 ILE   A CA    1 
ATOM   2570 C C     . ILE   D 2 253 ? 236.832 211.991 239.968 1.00 48.11  ? 265 ILE   A C     1 
ATOM   2571 O O     . ILE   D 2 253 ? 235.988 211.096 239.981 1.00 50.04  ? 265 ILE   A O     1 
ATOM   2572 C CB    . ILE   D 2 253 ? 236.725 214.097 241.369 1.00 47.86  ? 265 ILE   A CB    1 
ATOM   2573 C CG1   . ILE   D 2 253 ? 236.936 214.640 242.780 1.00 44.64  ? 265 ILE   A CG1   1 
ATOM   2574 C CG2   . ILE   D 2 253 ? 235.257 214.131 240.999 1.00 50.57  ? 265 ILE   A CG2   1 
ATOM   2575 C CD1   . ILE   D 2 253 ? 236.464 216.054 242.961 1.00 41.62  ? 265 ILE   A CD1   1 
ATOM   2576 N N     . LEU   D 2 254 ? 237.391 212.415 238.835 1.00 47.63  ? 266 LEU   A N     1 
ATOM   2577 C CA    . LEU   D 2 254 ? 237.136 211.766 237.550 1.00 47.33  ? 266 LEU   A CA    1 
ATOM   2578 C C     . LEU   D 2 254 ? 238.217 210.710 237.346 1.00 49.20  ? 266 LEU   A C     1 
ATOM   2579 O O     . LEU   D 2 254 ? 239.216 210.914 236.654 1.00 54.00  ? 266 LEU   A O     1 
ATOM   2580 C CB    . LEU   D 2 254 ? 237.116 212.789 236.423 1.00 46.85  ? 266 LEU   A CB    1 
ATOM   2581 C CG    . LEU   D 2 254 ? 236.265 214.035 236.656 1.00 45.65  ? 266 LEU   A CG    1 
ATOM   2582 C CD1   . LEU   D 2 254 ? 236.425 215.000 235.502 1.00 47.89  ? 266 LEU   A CD1   1 
ATOM   2583 C CD2   . LEU   D 2 254 ? 234.810 213.658 236.840 1.00 52.06  ? 266 LEU   A CD2   1 
ATOM   2584 N N     . ARG   D 2 255 ? 238.000 209.555 237.967 1.00 47.53  ? 267 ARG   A N     1 
ATOM   2585 C CA    . ARG   D 2 255 ? 239.038 208.545 238.089 1.00 48.18  ? 267 ARG   A CA    1 
ATOM   2586 C C     . ARG   D 2 255 ? 239.399 207.959 236.726 1.00 50.94  ? 267 ARG   A C     1 
ATOM   2587 O O     . ARG   D 2 255 ? 238.717 208.170 235.720 1.00 59.48  ? 267 ARG   A O     1 
ATOM   2588 C CB    . ARG   D 2 255 ? 238.588 207.440 239.039 1.00 49.71  ? 267 ARG   A CB    1 
ATOM   2589 C CG    . ARG   D 2 255 ? 238.708 207.806 240.500 1.00 49.37  ? 267 ARG   A CG    1 
ATOM   2590 C CD    . ARG   D 2 255 ? 237.742 207.000 241.338 1.00 47.60  ? 267 ARG   A CD    1 
ATOM   2591 N NE    . ARG   D 2 255 ? 236.571 207.782 241.711 1.00 44.73  ? 267 ARG   A NE    1 
ATOM   2592 C CZ    . ARG   D 2 255 ? 236.371 208.296 242.915 1.00 49.69  ? 267 ARG   A CZ    1 
ATOM   2593 N NH1   . ARG   D 2 255 ? 237.243 208.123 243.893 1.00 52.43  ? 267 ARG   A NH1   1 
ATOM   2594 N NH2   . ARG   D 2 255 ? 235.268 209.000 243.144 1.00 52.68  ? 267 ARG   A NH2   1 
ATOM   2595 N N     . GLY   D 2 256 ? 240.501 207.210 236.706 1.00 46.93  ? 268 GLY   A N     1 
ATOM   2596 C CA    . GLY   D 2 256 ? 241.007 206.594 235.503 1.00 49.42  ? 268 GLY   A CA    1 
ATOM   2597 C C     . GLY   D 2 256 ? 240.784 205.090 235.473 1.00 53.22  ? 268 GLY   A C     1 
ATOM   2598 O O     . GLY   D 2 256 ? 240.282 204.477 236.411 1.00 55.78  ? 268 GLY   A O     1 
ATOM   2599 N N     . SER   D 2 257 ? 241.183 204.501 234.350 1.00 55.30  ? 269 SER   A N     1 
ATOM   2600 C CA    . SER   D 2 257 ? 241.000 203.074 234.094 1.00 50.70  ? 269 SER   A CA    1 
ATOM   2601 C C     . SER   D 2 257 ? 242.289 202.350 234.468 1.00 51.80  ? 269 SER   A C     1 
ATOM   2602 O O     . SER   D 2 257 ? 243.215 202.235 233.667 1.00 54.72  ? 269 SER   A O     1 
ATOM   2603 C CB    . SER   D 2 257 ? 240.622 202.832 232.638 1.00 50.25  ? 269 SER   A CB    1 
ATOM   2604 O OG    . SER   D 2 257 ? 239.401 203.469 232.315 1.00 56.37  ? 269 SER   A OG    1 
ATOM   2605 N N     . VAL   D 2 258 ? 242.337 201.842 235.694 1.00 51.82  ? 270 VAL   A N     1 
ATOM   2606 C CA    . VAL   D 2 258 ? 243.490 201.114 236.208 1.00 52.63  ? 270 VAL   A CA    1 
ATOM   2607 C C     . VAL   D 2 258 ? 243.102 199.650 236.347 1.00 54.42  ? 270 VAL   A C     1 
ATOM   2608 O O     . VAL   D 2 258 ? 242.090 199.327 236.980 1.00 59.78  ? 270 VAL   A O     1 
ATOM   2609 C CB    . VAL   D 2 258 ? 243.966 201.693 237.549 1.00 54.06  ? 270 VAL   A CB    1 
ATOM   2610 C CG1   . VAL   D 2 258 ? 245.128 200.893 238.088 1.00 51.89  ? 270 VAL   A CG1   1 
ATOM   2611 C CG2   . VAL   D 2 258 ? 244.350 203.149 237.381 1.00 54.82  ? 270 VAL   A CG2   1 
ATOM   2612 N N     . ALA   D 2 259 ? 243.905 198.767 235.760 1.00 51.18  ? 271 ALA   A N     1 
ATOM   2613 C CA    . ALA   D 2 259 ? 243.592 197.346 235.719 1.00 53.51  ? 271 ALA   A CA    1 
ATOM   2614 C C     . ALA   D 2 259 ? 244.053 196.667 237.000 1.00 54.61  ? 271 ALA   A C     1 
ATOM   2615 O O     . ALA   D 2 259 ? 245.217 196.788 237.393 1.00 54.49  ? 271 ALA   A O     1 
ATOM   2616 C CB    . ALA   D 2 259 ? 244.246 196.684 234.507 1.00 54.39  ? 271 ALA   A CB    1 
ATOM   2617 N N     . HIS   D 2 260 ? 243.138 195.951 237.643 1.00 55.20  ? 272 HIS   A N     1 
ATOM   2618 C CA    . HIS   D 2 260 ? 243.411 195.255 238.892 1.00 52.29  ? 272 HIS   A CA    1 
ATOM   2619 C C     . HIS   D 2 260 ? 243.378 193.753 238.655 1.00 54.64  ? 272 HIS   A C     1 
ATOM   2620 O O     . HIS   D 2 260 ? 242.402 193.227 238.112 1.00 58.32  ? 272 HIS   A O     1 
ATOM   2621 C CB    . HIS   D 2 260 ? 242.396 195.647 239.965 1.00 49.77  ? 272 HIS   A CB    1 
ATOM   2622 C CG    . HIS   D 2 260 ? 242.469 197.086 240.365 1.00 52.21  ? 272 HIS   A CG    1 
ATOM   2623 N ND1   . HIS   D 2 260 ? 241.733 198.071 239.742 1.00 52.17  ? 272 HIS   A ND1   1 
ATOM   2624 C CD2   . HIS   D 2 260 ? 243.188 197.707 241.329 1.00 52.63  ? 272 HIS   A CD2   1 
ATOM   2625 C CE1   . HIS   D 2 260 ? 241.999 199.236 240.303 1.00 49.67  ? 272 HIS   A CE1   1 
ATOM   2626 N NE2   . HIS   D 2 260 ? 242.878 199.043 241.270 1.00 50.45  ? 272 HIS   A NE2   1 
ATOM   2627 N N     . LYS   D 2 261 ? 244.446 193.071 239.056 1.00 49.21  ? 273 LYS   A N     1 
ATOM   2628 C CA    . LYS   D 2 261 ? 244.560 191.630 238.908 1.00 47.49  ? 273 LYS   A CA    1 
ATOM   2629 C C     . LYS   D 2 261 ? 245.000 191.018 240.228 1.00 50.54  ? 273 LYS   A C     1 
ATOM   2630 O O     . LYS   D 2 261 ? 245.740 191.633 240.999 1.00 59.10  ? 273 LYS   A O     1 
ATOM   2631 C CB    . LYS   D 2 261 ? 245.559 191.253 237.805 1.00 48.24  ? 273 LYS   A CB    1 
ATOM   2632 C CG    . LYS   D 2 261 ? 245.296 191.913 236.465 1.00 50.25  ? 273 LYS   A CG    1 
ATOM   2633 C CD    . LYS   D 2 261 ? 246.556 191.952 235.621 1.00 51.93  ? 273 LYS   A CD    1 
ATOM   2634 C CE    . LYS   D 2 261 ? 246.249 192.336 234.189 1.00 48.98  ? 273 LYS   A CE    1 
ATOM   2635 N NZ    . LYS   D 2 261 ? 244.848 192.004 233.830 1.00 57.95  ? 273 LYS   A NZ    1 
ATOM   2636 N N     . SER   D 2 262 ? 244.531 189.800 240.487 1.00 46.18  ? 274 SER   A N     1 
ATOM   2637 C CA    . SER   D 2 262 ? 244.926 189.054 241.680 1.00 45.01  ? 274 SER   A CA    1 
ATOM   2638 C C     . SER   D 2 262 ? 246.135 188.199 241.330 1.00 50.02  ? 274 SER   A C     1 
ATOM   2639 O O     . SER   D 2 262 ? 246.009 187.150 240.695 1.00 52.48  ? 274 SER   A O     1 
ATOM   2640 C CB    . SER   D 2 262 ? 243.775 188.201 242.199 1.00 45.18  ? 274 SER   A CB    1 
ATOM   2641 O OG    . SER   D 2 262 ? 242.783 189.000 242.810 1.00 49.84  ? 274 SER   A OG    1 
ATOM   2642 N N     . CYS   D 2 263 ? 247.310 188.645 241.753 1.00 49.68  ? 275 CYS   A N     1 
ATOM   2643 C CA    . CYS   D 2 263 ? 248.562 187.936 241.514 1.00 49.16  ? 275 CYS   A CA    1 
ATOM   2644 C C     . CYS   D 2 263 ? 249.032 187.361 242.845 1.00 48.90  ? 275 CYS   A C     1 
ATOM   2645 O O     . CYS   D 2 263 ? 249.534 188.088 243.706 1.00 49.08  ? 275 CYS   A O     1 
ATOM   2646 C CB    . CYS   D 2 263 ? 249.594 188.866 240.890 1.00 48.86  ? 275 CYS   A CB    1 
ATOM   2647 S SG    . CYS   D 2 263 ? 249.032 189.615 239.349 1.00 59.02  ? 275 CYS   A SG    1 
ATOM   2648 N N     . LEU   D 2 264 ? 248.867 186.055 243.005 1.00 48.89  ? 276 LEU   A N     1 
ATOM   2649 C CA    . LEU   D 2 264 ? 249.163 185.370 244.250 1.00 48.14  ? 276 LEU   A CA    1 
ATOM   2650 C C     . LEU   D 2 264 ? 250.651 185.050 244.357 1.00 51.19  ? 276 LEU   A C     1 
ATOM   2651 O O     . LEU   D 2 264 ? 251.360 185.000 243.350 1.00 53.28  ? 276 LEU   A O     1 
ATOM   2652 C CB    . LEU   D 2 264 ? 248.343 184.087 244.341 1.00 49.17  ? 276 LEU   A CB    1 
ATOM   2653 C CG    . LEU   D 2 264 ? 246.830 184.213 244.171 1.00 49.19  ? 276 LEU   A CG    1 
ATOM   2654 C CD1   . LEU   D 2 264 ? 246.152 182.913 244.551 1.00 50.77  ? 276 LEU   A CD1   1 
ATOM   2655 C CD2   . LEU   D 2 264 ? 246.285 185.358 245.000 1.00 49.16  ? 276 LEU   A CD2   1 
ATOM   2656 N N     . PRO   D 2 265 ? 251.153 184.835 245.572 1.00 50.43  ? 277 PRO   A N     1 
ATOM   2657 C CA    . PRO   D 2 265 ? 252.548 184.409 245.722 1.00 49.05  ? 277 PRO   A CA    1 
ATOM   2658 C C     . PRO   D 2 265 ? 252.770 183.032 245.120 1.00 51.21  ? 277 PRO   A C     1 
ATOM   2659 O O     . PRO   D 2 265 ? 251.848 182.222 245.000 1.00 57.64  ? 277 PRO   A O     1 
ATOM   2660 C CB    . PRO   D 2 265 ? 252.759 184.394 247.240 1.00 48.00  ? 277 PRO   A CB    1 
ATOM   2661 C CG    . PRO   D 2 265 ? 251.394 184.308 247.818 1.00 46.90  ? 277 PRO   A CG    1 
ATOM   2662 C CD    . PRO   D 2 265 ? 250.507 185.055 246.876 1.00 47.78  ? 277 PRO   A CD    1 
ATOM   2663 N N     . ALA   D 2 266 ? 254.020 182.774 244.734 1.00 50.72  ? 278 ALA   A N     1 
ATOM   2664 C CA    . ALA   D 2 266 ? 254.342 181.527 244.050 1.00 50.89  ? 278 ALA   A CA    1 
ATOM   2665 C C     . ALA   D 2 266 ? 254.133 180.303 244.930 1.00 50.29  ? 278 ALA   A C     1 
ATOM   2666 O O     . ALA   D 2 266 ? 254.039 179.191 244.405 1.00 51.97  ? 278 ALA   A O     1 
ATOM   2667 C CB    . ALA   D 2 266 ? 255.783 181.559 243.542 1.00 48.09  ? 278 ALA   A CB    1 
ATOM   2668 N N     . CYS   D 2 267 ? 254.068 180.474 246.252 1.00 50.08  ? 279 CYS   A N     1 
ATOM   2669 C CA    . CYS   D 2 267 ? 253.840 179.330 247.129 1.00 49.49  ? 279 CYS   A CA    1 
ATOM   2670 C C     . CYS   D 2 267 ? 252.474 178.704 246.876 1.00 47.60  ? 279 CYS   A C     1 
ATOM   2671 O O     . CYS   D 2 267 ? 252.342 177.475 246.845 1.00 49.46  ? 279 CYS   A O     1 
ATOM   2672 C CB    . CYS   D 2 267 ? 253.983 179.753 248.590 1.00 51.06  ? 279 CYS   A CB    1 
ATOM   2673 S SG    . CYS   D 2 267 ? 252.944 181.141 249.070 1.00 77.39  ? 279 CYS   A SG    1 
ATOM   2674 N N     . VAL   D 2 268 ? 251.450 179.537 246.677 1.00 48.41  ? 280 VAL   A N     1 
ATOM   2675 C CA    . VAL   D 2 268 ? 250.105 179.030 246.411 1.00 49.93  ? 280 VAL   A CA    1 
ATOM   2676 C C     . VAL   D 2 268 ? 250.073 178.271 245.090 1.00 49.86  ? 280 VAL   A C     1 
ATOM   2677 O O     . VAL   D 2 268 ? 249.517 177.169 244.998 1.00 49.55  ? 280 VAL   A O     1 
ATOM   2678 C CB    . VAL   D 2 268 ? 249.089 180.186 246.419 1.00 51.49  ? 280 VAL   A CB    1 
ATOM   2679 C CG1   . VAL   D 2 268 ? 247.675 179.645 246.434 1.00 54.44  ? 280 VAL   A CG1   1 
ATOM   2680 C CG2   . VAL   D 2 268 ? 249.327 181.092 247.609 1.00 47.80  ? 280 VAL   A CG2   1 
ATOM   2681 N N     . TYR   D 2 269 ? 250.674 178.851 244.049 1.00 50.70  ? 281 TYR   A N     1 
ATOM   2682 C CA    . TYR   D 2 269 ? 250.706 178.191 242.748 1.00 50.13  ? 281 TYR   A CA    1 
ATOM   2683 C C     . TYR   D 2 269 ? 251.471 176.877 242.815 1.00 49.52  ? 281 TYR   A C     1 
ATOM   2684 O O     . TYR   D 2 269 ? 251.055 175.877 242.221 1.00 49.18  ? 281 TYR   A O     1 
ATOM   2685 C CB    . TYR   D 2 269 ? 251.331 179.114 241.702 1.00 50.65  ? 281 TYR   A CB    1 
ATOM   2686 C CG    . TYR   D 2 269 ? 250.582 180.405 241.462 1.00 53.15  ? 281 TYR   A CG    1 
ATOM   2687 C CD1   . TYR   D 2 269 ? 249.198 180.454 241.522 1.00 52.17  ? 281 TYR   A CD1   1 
ATOM   2688 C CD2   . TYR   D 2 269 ? 251.263 181.575 241.162 1.00 53.94  ? 281 TYR   A CD2   1 
ATOM   2689 C CE1   . TYR   D 2 269 ? 248.516 181.634 241.295 1.00 50.07  ? 281 TYR   A CE1   1 
ATOM   2690 C CE2   . TYR   D 2 269 ? 250.591 182.757 240.937 1.00 50.95  ? 281 TYR   A CE2   1 
ATOM   2691 C CZ    . TYR   D 2 269 ? 249.219 182.782 241.003 1.00 47.36  ? 281 TYR   A CZ    1 
ATOM   2692 O OH    . TYR   D 2 269 ? 248.553 183.961 240.778 1.00 48.45  ? 281 TYR   A OH    1 
ATOM   2693 N N     . GLY   D 2 270 ? 252.597 176.864 243.529 1.00 49.59  ? 282 GLY   A N     1 
ATOM   2694 C CA    . GLY   D 2 270 ? 253.374 175.643 243.647 1.00 49.37  ? 282 GLY   A CA    1 
ATOM   2695 C C     . GLY   D 2 270 ? 252.636 174.552 244.396 1.00 51.54  ? 282 GLY   A C     1 
ATOM   2696 O O     . GLY   D 2 270 ? 252.675 173.384 244.001 1.00 55.77  ? 282 GLY   A O     1 
ATOM   2697 N N     . SER   D 2 271 ? 251.951 174.916 245.482 1.00 50.26  ? 283 SER   A N     1 
ATOM   2698 C CA    . SER   D 2 271 ? 251.143 173.940 246.204 1.00 47.78  ? 283 SER   A CA    1 
ATOM   2699 C C     . SER   D 2 271 ? 250.024 173.399 245.323 1.00 51.58  ? 283 SER   A C     1 
ATOM   2700 O O     . SER   D 2 271 ? 249.745 172.195 245.332 1.00 55.78  ? 283 SER   A O     1 
ATOM   2701 C CB    . SER   D 2 271 ? 250.575 174.569 247.476 1.00 49.98  ? 283 SER   A CB    1 
ATOM   2702 O OG    . SER   D 2 271 ? 249.304 174.034 247.795 1.00 46.49  ? 283 SER   A OG    1 
ATOM   2703 N N     . ALA   D 2 272 ? 249.382 174.273 244.544 1.00 49.30  ? 284 ALA   A N     1 
ATOM   2704 C CA    . ALA   D 2 272 ? 248.312 173.827 243.657 1.00 48.99  ? 284 ALA   A CA    1 
ATOM   2705 C C     . ALA   D 2 272 ? 248.832 172.884 242.578 1.00 51.73  ? 284 ALA   A C     1 
ATOM   2706 O O     . ALA   D 2 272 ? 248.173 171.894 242.243 1.00 53.00  ? 284 ALA   A O     1 
ATOM   2707 C CB    . ALA   D 2 272 ? 247.622 175.033 243.024 1.00 49.80  ? 284 ALA   A CB    1 
ATOM   2708 N N     . VAL   D 2 273 ? 250.001 173.180 242.010 1.00 51.50  ? 285 VAL   A N     1 
ATOM   2709 C CA    . VAL   D 2 273 ? 250.550 172.324 240.963 1.00 50.76  ? 285 VAL   A CA    1 
ATOM   2710 C C     . VAL   D 2 273 ? 251.000 170.989 241.541 1.00 52.70  ? 285 VAL   A C     1 
ATOM   2711 O O     . VAL   D 2 273 ? 250.811 169.936 240.922 1.00 56.65  ? 285 VAL   A O     1 
ATOM   2712 C CB    . VAL   D 2 273 ? 251.691 173.042 240.223 1.00 50.58  ? 285 VAL   A CB    1 
ATOM   2713 C CG1   . VAL   D 2 273 ? 252.358 172.104 239.237 1.00 53.87  ? 285 VAL   A CG1   1 
ATOM   2714 C CG2   . VAL   D 2 273 ? 251.159 174.262 239.503 1.00 50.66  ? 285 VAL   A CG2   1 
ATOM   2715 N N     . ALA   D 2 274 ? 251.593 171.004 242.737 1.00 51.64  ? 286 ALA   A N     1 
ATOM   2716 C CA    . ALA   D 2 274 ? 251.962 169.750 243.383 1.00 53.51  ? 286 ALA   A CA    1 
ATOM   2717 C C     . ALA   D 2 274 ? 250.734 168.946 243.791 1.00 55.74  ? 286 ALA   A C     1 
ATOM   2718 O O     . ALA   D 2 274 ? 250.813 167.719 243.912 1.00 57.80  ? 286 ALA   A O     1 
ATOM   2719 C CB    . ALA   D 2 274 ? 252.847 170.024 244.597 1.00 53.41  ? 286 ALA   A CB    1 
ATOM   2720 N N     . SER   D 2 275 ? 249.599 169.613 244.011 1.00 54.12  ? 287 SER   A N     1 
ATOM   2721 C CA    . SER   D 2 275 ? 248.376 168.894 244.350 1.00 53.31  ? 287 SER   A CA    1 
ATOM   2722 C C     . SER   D 2 275 ? 247.819 168.135 243.153 1.00 57.99  ? 287 SER   A C     1 
ATOM   2723 O O     . SER   D 2 275 ? 247.220 167.069 243.323 1.00 61.52  ? 287 SER   A O     1 
ATOM   2724 C CB    . SER   D 2 275 ? 247.327 169.863 244.893 1.00 52.06  ? 287 SER   A CB    1 
ATOM   2725 O OG    . SER   D 2 275 ? 247.674 170.314 246.188 1.00 62.59  ? 287 SER   A OG    1 
ATOM   2726 N N     . GLY   D 2 276 ? 248.000 168.662 241.946 1.00 56.78  ? 288 GLY   A N     1 
ATOM   2727 C CA    . GLY   D 2 276 ? 247.507 168.000 240.755 1.00 51.47  ? 288 GLY   A CA    1 
ATOM   2728 C C     . GLY   D 2 276 ? 246.478 168.810 239.995 1.00 55.33  ? 288 GLY   A C     1 
ATOM   2729 O O     . GLY   D 2 276 ? 245.629 168.247 239.299 1.00 60.86  ? 288 GLY   A O     1 
ATOM   2730 N N     . TYR   D 2 277 ? 246.540 170.133 240.119 1.00 53.21  ? 289 TYR   A N     1 
ATOM   2731 C CA    . TYR   D 2 277 ? 245.605 171.025 239.441 1.00 54.72  ? 289 TYR   A CA    1 
ATOM   2732 C C     . TYR   D 2 277 ? 246.215 171.448 238.109 1.00 57.34  ? 289 TYR   A C     1 
ATOM   2733 O O     . TYR   D 2 277 ? 247.227 172.153 238.078 1.00 60.35  ? 289 TYR   A O     1 
ATOM   2734 C CB    . TYR   D 2 277 ? 245.289 172.235 240.315 1.00 55.66  ? 289 TYR   A CB    1 
ATOM   2735 C CG    . TYR   D 2 277 ? 244.054 173.000 239.898 1.00 59.11  ? 289 TYR   A CG    1 
ATOM   2736 C CD1   . TYR   D 2 277 ? 242.806 172.668 240.401 1.00 62.35  ? 289 TYR   A CD1   1 
ATOM   2737 C CD2   . TYR   D 2 277 ? 244.138 174.056 239.005 1.00 58.48  ? 289 TYR   A CD2   1 
ATOM   2738 C CE1   . TYR   D 2 277 ? 241.677 173.365 240.024 1.00 58.35  ? 289 TYR   A CE1   1 
ATOM   2739 C CE2   . TYR   D 2 277 ? 243.014 174.759 238.625 1.00 56.21  ? 289 TYR   A CE2   1 
ATOM   2740 C CZ    . TYR   D 2 277 ? 241.788 174.408 239.136 1.00 57.04  ? 289 TYR   A CZ    1 
ATOM   2741 O OH    . TYR   D 2 277 ? 240.666 175.105 238.759 1.00 60.63  ? 289 TYR   A OH    1 
ATOM   2742 N N     . ASP   D 2 278 ? 245.604 171.014 237.011 1.00 55.20  ? 290 ASP   A N     1 
ATOM   2743 C CA    . ASP   D 2 278 ? 246.084 171.350 235.674 1.00 55.41  ? 290 ASP   A CA    1 
ATOM   2744 C C     . ASP   D 2 278 ? 245.460 172.678 235.269 1.00 55.38  ? 290 ASP   A C     1 
ATOM   2745 O O     . ASP   D 2 278 ? 244.315 172.728 234.817 1.00 56.28  ? 290 ASP   A O     1 
ATOM   2746 C CB    . ASP   D 2 278 ? 245.748 170.242 234.683 1.00 58.18  ? 290 ASP   A CB    1 
ATOM   2747 C CG    . ASP   D 2 278 ? 246.756 170.142 233.558 1.00 59.64  ? 290 ASP   A CG    1 
ATOM   2748 O OD1   . ASP   D 2 278 ? 247.000 171.163 232.888 1.00 61.87  ? 290 ASP   A OD1   1 
ATOM   2749 O OD2   . ASP   D 2 278 ? 247.303 169.043 233.340 1.00 62.35  ? 290 ASP   A OD2   1 
ATOM   2750 N N     . PHE   D 2 279 ? 246.214 173.764 235.447 1.00 55.40  ? 291 PHE   A N     1 
ATOM   2751 C CA    . PHE   D 2 279 ? 245.717 175.077 235.051 1.00 54.63  ? 291 PHE   A CA    1 
ATOM   2752 C C     . PHE   D 2 279 ? 245.529 175.167 233.545 1.00 55.23  ? 291 PHE   A C     1 
ATOM   2753 O O     . PHE   D 2 279 ? 244.705 175.955 233.069 1.00 57.49  ? 291 PHE   A O     1 
ATOM   2754 C CB    . PHE   D 2 279 ? 246.673 176.169 235.526 1.00 54.83  ? 291 PHE   A CB    1 
ATOM   2755 C CG    . PHE   D 2 279 ? 246.788 176.277 237.016 1.00 52.40  ? 291 PHE   A CG    1 
ATOM   2756 C CD1   . PHE   D 2 279 ? 245.834 176.954 237.750 1.00 50.26  ? 291 PHE   A CD1   1 
ATOM   2757 C CD2   . PHE   D 2 279 ? 247.863 175.719 237.681 1.00 53.63  ? 291 PHE   A CD2   1 
ATOM   2758 C CE1   . PHE   D 2 279 ? 245.944 177.061 239.118 1.00 52.36  ? 291 PHE   A CE1   1 
ATOM   2759 C CE2   . PHE   D 2 279 ? 247.977 175.824 239.048 1.00 52.10  ? 291 PHE   A CE2   1 
ATOM   2760 C CZ    . PHE   D 2 279 ? 247.016 176.494 239.768 1.00 54.41  ? 291 PHE   A CZ    1 
ATOM   2761 N N     . GLU   D 2 280 ? 246.290 174.381 232.783 1.00 55.38  ? 292 GLU   A N     1 
ATOM   2762 C CA    . GLU   D 2 280 ? 246.137 174.374 231.334 1.00 55.64  ? 292 GLU   A CA    1 
ATOM   2763 C C     . GLU   D 2 280 ? 244.763 173.859 230.924 1.00 57.12  ? 292 GLU   A C     1 
ATOM   2764 O O     . GLU   D 2 280 ? 244.124 174.415 230.025 1.00 55.99  ? 292 GLU   A O     1 
ATOM   2765 C CB    . GLU   D 2 280 ? 247.241 173.525 230.707 1.00 56.06  ? 292 GLU   A CB    1 
ATOM   2766 C CG    . GLU   D 2 280 ? 247.299 173.586 229.202 1.00 61.46  ? 292 GLU   A CG    1 
ATOM   2767 C CD    . GLU   D 2 280 ? 248.366 174.530 228.711 1.00 71.25  ? 292 GLU   A CD    1 
ATOM   2768 O OE1   . GLU   D 2 280 ? 248.063 175.728 228.536 1.00 73.99  ? 292 GLU   A OE1   1 
ATOM   2769 O OE2   . GLU   D 2 280 ? 249.510 174.076 228.505 1.00 76.31  ? 292 GLU   A OE2   1 
ATOM   2770 N N     . ARG   D 2 281 ? 244.292 172.794 231.573 1.00 56.25  ? 293 ARG   A N     1 
ATOM   2771 C CA    . ARG   D 2 281 ? 242.999 172.225 231.217 1.00 57.88  ? 293 ARG   A CA    1 
ATOM   2772 C C     . ARG   D 2 281 ? 241.848 173.013 231.828 1.00 57.39  ? 293 ARG   A C     1 
ATOM   2773 O O     . ARG   D 2 281 ? 240.858 173.296 231.146 1.00 63.14  ? 293 ARG   A O     1 
ATOM   2774 C CB    . ARG   D 2 281 ? 242.928 170.764 231.658 1.00 61.24  ? 293 ARG   A CB    1 
ATOM   2775 C CG    . ARG   D 2 281 ? 243.952 169.862 230.997 1.00 66.00  ? 293 ARG   A CG    1 
ATOM   2776 C CD    . ARG   D 2 281 ? 243.412 168.462 230.685 1.00 70.08  ? 293 ARG   A CD    1 
ATOM   2777 N NE    . ARG   D 2 281 ? 242.186 168.102 231.390 1.00 78.51  ? 293 ARG   A NE    1 
ATOM   2778 C CZ    . ARG   D 2 281 ? 242.100 167.865 232.693 1.00 86.37  ? 293 ARG   A CZ    1 
ATOM   2779 N NH1   . ARG   D 2 281 ? 243.164 167.919 233.478 1.00 83.34  ? 293 ARG   A NH1   1 
ATOM   2780 N NH2   . ARG   D 2 281 ? 240.918 167.561 233.221 1.00 88.30  ? 293 ARG   A NH2   1 
ATOM   2781 N N     . GLU   D 2 282 ? 241.955 173.369 233.108 1.00 53.50  ? 294 GLU   A N     1 
ATOM   2782 C CA    . GLU   D 2 282 ? 240.865 174.085 233.760 1.00 54.53  ? 294 GLU   A CA    1 
ATOM   2783 C C     . GLU   D 2 282 ? 240.809 175.542 233.319 1.00 56.35  ? 294 GLU   A C     1 
ATOM   2784 O O     . GLU   D 2 282 ? 239.723 176.083 233.086 1.00 61.01  ? 294 GLU   A O     1 
ATOM   2785 C CB    . GLU   D 2 282 ? 241.008 173.985 235.277 1.00 58.38  ? 294 GLU   A CB    1 
ATOM   2786 C CG    . GLU   D 2 282 ? 240.053 172.999 235.921 1.00 57.71  ? 294 GLU   A CG    1 
ATOM   2787 C CD    . GLU   D 2 282 ? 240.629 171.603 236.000 1.00 61.33  ? 294 GLU   A CD    1 
ATOM   2788 O OE1   . GLU   D 2 282 ? 241.773 171.405 235.547 1.00 67.08  ? 294 GLU   A OE1   1 
ATOM   2789 O OE2   . GLU   D 2 282 ? 239.940 170.703 236.520 1.00 65.64  ? 294 GLU   A OE2   1 
ATOM   2790 N N     . GLY   D 2 283 ? 241.956 176.188 233.196 1.00 54.98  ? 295 GLY   A N     1 
ATOM   2791 C CA    . GLY   D 2 283 ? 241.976 177.590 232.808 1.00 51.56  ? 295 GLY   A CA    1 
ATOM   2792 C C     . GLY   D 2 283 ? 241.990 178.516 234.006 1.00 52.38  ? 295 GLY   A C     1 
ATOM   2793 O O     . GLY   D 2 283 ? 241.418 178.235 235.058 1.00 58.94  ? 295 GLY   A O     1 
ATOM   2794 N N     . TYR   D 2 284 ? 242.654 179.654 233.836 1.00 51.65  ? 296 TYR   A N     1 
ATOM   2795 C CA    . TYR   D 2 284 ? 242.827 180.613 234.914 1.00 51.90  ? 296 TYR   A CA    1 
ATOM   2796 C C     . TYR   D 2 284 ? 242.457 182.011 234.442 1.00 52.35  ? 296 TYR   A C     1 
ATOM   2797 O O     . TYR   D 2 284 ? 242.688 182.381 233.289 1.00 52.58  ? 296 TYR   A O     1 
ATOM   2798 C CB    . TYR   D 2 284 ? 244.264 180.608 235.436 1.00 52.47  ? 296 TYR   A CB    1 
ATOM   2799 C CG    . TYR   D 2 284 ? 244.385 180.997 236.887 1.00 51.35  ? 296 TYR   A CG    1 
ATOM   2800 C CD1   . TYR   D 2 284 ? 244.000 180.124 237.892 1.00 50.07  ? 296 TYR   A CD1   1 
ATOM   2801 C CD2   . TYR   D 2 284 ? 244.888 182.236 237.251 1.00 52.10  ? 296 TYR   A CD2   1 
ATOM   2802 C CE1   . TYR   D 2 284 ? 244.111 180.475 239.219 1.00 50.48  ? 296 TYR   A CE1   1 
ATOM   2803 C CE2   . TYR   D 2 284 ? 245.000 182.596 238.574 1.00 52.54  ? 296 TYR   A CE2   1 
ATOM   2804 C CZ    . TYR   D 2 284 ? 244.613 181.713 239.553 1.00 53.81  ? 296 TYR   A CZ    1 
ATOM   2805 O OH    . TYR   D 2 284 ? 244.727 182.070 240.873 1.00 60.01  ? 296 TYR   A OH    1 
ATOM   2806 N N     . SER   D 2 285 ? 241.878 182.783 235.355 1.00 53.33  ? 297 SER   A N     1 
ATOM   2807 C CA    . SER   D 2 285 ? 241.534 184.176 235.125 1.00 50.74  ? 297 SER   A CA    1 
ATOM   2808 C C     . SER   D 2 285 ? 242.015 185.001 236.307 1.00 51.21  ? 297 SER   A C     1 
ATOM   2809 O O     . SER   D 2 285 ? 241.831 184.609 237.461 1.00 55.45  ? 297 SER   A O     1 
ATOM   2810 C CB    . SER   D 2 285 ? 240.024 184.359 234.940 1.00 50.61  ? 297 SER   A CB    1 
ATOM   2811 O OG    . SER   D 2 285 ? 239.733 185.590 234.306 1.00 50.22  ? 297 SER   A OG    1 
ATOM   2812 N N     . LEU   D 2 286 ? 242.636 186.139 236.017 1.00 50.80  ? 298 LEU   A N     1 
ATOM   2813 C CA    . LEU   D 2 286 ? 243.144 187.020 237.059 1.00 50.97  ? 298 LEU   A CA    1 
ATOM   2814 C C     . LEU   D 2 286 ? 242.099 188.000 237.572 1.00 53.37  ? 298 LEU   A C     1 
ATOM   2815 O O     . LEU   D 2 286 ? 242.391 188.765 238.495 1.00 54.71  ? 298 LEU   A O     1 
ATOM   2816 C CB    . LEU   D 2 286 ? 244.362 187.797 236.549 1.00 49.14  ? 298 LEU   A CB    1 
ATOM   2817 C CG    . LEU   D 2 286 ? 245.539 186.979 236.027 1.00 47.28  ? 298 LEU   A CG    1 
ATOM   2818 C CD1   . LEU   D 2 286 ? 246.724 187.881 235.754 1.00 47.45  ? 298 LEU   A CD1   1 
ATOM   2819 C CD2   . LEU   D 2 286 ? 245.910 185.893 237.015 1.00 50.93  ? 298 LEU   A CD2   1 
ATOM   2820 N N     . VAL   D 2 287 ? 240.896 188.001 237.001 1.00 53.31  ? 299 VAL   A N     1 
ATOM   2821 C CA    . VAL   D 2 287 ? 239.843 188.926 237.386 1.00 51.85  ? 299 VAL   A CA    1 
ATOM   2822 C C     . VAL   D 2 287 ? 238.572 188.206 237.818 1.00 52.60  ? 299 VAL   A C     1 
ATOM   2823 O O     . VAL   D 2 287 ? 237.547 188.847 238.036 1.00 54.74  ? 299 VAL   A O     1 
ATOM   2824 C CB    . VAL   D 2 287 ? 239.540 189.927 236.253 1.00 49.61  ? 299 VAL   A CB    1 
ATOM   2825 C CG1   . VAL   D 2 287 ? 240.761 190.774 235.958 1.00 51.41  ? 299 VAL   A CG1   1 
ATOM   2826 C CG2   . VAL   D 2 287 ? 239.087 189.190 235.010 1.00 50.11  ? 299 VAL   A CG2   1 
ATOM   2827 N N     . GLY   D 2 288 ? 238.618 186.883 237.951 1.00 53.57  ? 300 GLY   A N     1 
ATOM   2828 C CA    . GLY   D 2 288 ? 237.423 186.125 238.262 1.00 51.25  ? 300 GLY   A CA    1 
ATOM   2829 C C     . GLY   D 2 288 ? 237.484 185.355 239.563 1.00 55.53  ? 300 GLY   A C     1 
ATOM   2830 O O     . GLY   D 2 288 ? 238.092 185.807 240.537 1.00 60.50  ? 300 GLY   A O     1 
ATOM   2831 N N     . ILE   D 2 289 ? 236.853 184.179 239.588 1.00 53.71  ? 301 ILE   A N     1 
ATOM   2832 C CA    . ILE   D 2 289 ? 236.776 183.378 240.808 1.00 53.78  ? 301 ILE   A CA    1 
ATOM   2833 C C     . ILE   D 2 289 ? 237.998 182.505 241.026 1.00 53.64  ? 301 ILE   A C     1 
ATOM   2834 O O     . ILE   D 2 289 ? 238.194 182.000 242.138 1.00 56.01  ? 301 ILE   A O     1 
ATOM   2835 C CB    . ILE   D 2 289 ? 235.514 182.494 240.783 1.00 51.97  ? 301 ILE   A CB    1 
ATOM   2836 C CG1   . ILE   D 2 289 ? 235.163 182.000 242.187 1.00 50.65  ? 301 ILE   A CG1   1 
ATOM   2837 C CG2   . ILE   D 2 289 ? 235.701 181.327 239.833 1.00 53.03  ? 301 ILE   A CG2   1 
ATOM   2838 C CD1   . ILE   D 2 289 ? 233.963 181.093 242.230 1.00 57.30  ? 301 ILE   A CD1   1 
ATOM   2839 N N     . ASP   D 2 290 ? 238.829 182.316 240.003 1.00 51.58  ? 302 ASP   A N     1 
ATOM   2840 C CA    . ASP   D 2 290 ? 239.952 181.388 240.125 1.00 52.07  ? 302 ASP   A CA    1 
ATOM   2841 C C     . ASP   D 2 290 ? 240.911 181.752 241.253 1.00 52.35  ? 302 ASP   A C     1 
ATOM   2842 O O     . ASP   D 2 290 ? 241.268 180.856 242.036 1.00 51.40  ? 302 ASP   A O     1 
ATOM   2843 C CB    . ASP   D 2 290 ? 240.673 181.282 238.779 1.00 54.11  ? 302 ASP   A CB    1 
ATOM   2844 C CG    . ASP   D 2 290 ? 239.836 180.587 237.728 1.00 55.07  ? 302 ASP   A CG    1 
ATOM   2845 O OD1   . ASP   D 2 290 ? 239.009 181.260 237.083 1.00 56.48  ? 302 ASP   A OD1   1 
ATOM   2846 O OD2   . ASP   D 2 290 ? 240.000 179.363 237.552 1.00 57.45  ? 302 ASP   A OD2   1 
ATOM   2847 N N     . PRO   D 2 291 ? 241.367 183.004 241.404 1.00 53.27  ? 303 PRO   A N     1 
ATOM   2848 C CA    . PRO   D 2 291 ? 242.232 183.308 242.558 1.00 52.30  ? 303 PRO   A CA    1 
ATOM   2849 C C     . PRO   D 2 291 ? 241.542 183.120 243.897 1.00 50.20  ? 303 PRO   A C     1 
ATOM   2850 O O     . PRO   D 2 291 ? 242.173 182.659 244.854 1.00 52.32  ? 303 PRO   A O     1 
ATOM   2851 C CB    . PRO   D 2 291 ? 242.632 184.771 242.320 1.00 51.29  ? 303 PRO   A CB    1 
ATOM   2852 C CG    . PRO   D 2 291 ? 242.359 185.024 240.885 1.00 47.76  ? 303 PRO   A CG    1 
ATOM   2853 C CD    . PRO   D 2 291 ? 241.174 184.192 240.556 1.00 51.97  ? 303 PRO   A CD    1 
ATOM   2854 N N     . PHE   D 2 292 ? 240.255 183.460 243.989 1.00 49.75  ? 304 PHE   A N     1 
ATOM   2855 C CA    . PHE   D 2 292 ? 239.525 183.273 245.239 1.00 49.47  ? 304 PHE   A CA    1 
ATOM   2856 C C     . PHE   D 2 292 ? 239.421 181.797 245.596 1.00 50.65  ? 304 PHE   A C     1 
ATOM   2857 O O     . PHE   D 2 292 ? 239.677 181.403 246.742 1.00 52.84  ? 304 PHE   A O     1 
ATOM   2858 C CB    . PHE   D 2 292 ? 238.132 183.888 245.120 1.00 50.07  ? 304 PHE   A CB    1 
ATOM   2859 C CG    . PHE   D 2 292 ? 238.088 185.354 245.421 1.00 49.11  ? 304 PHE   A CG    1 
ATOM   2860 C CD1   . PHE   D 2 292 ? 238.064 185.806 246.725 1.00 50.88  ? 304 PHE   A CD1   1 
ATOM   2861 C CD2   . PHE   D 2 292 ? 238.067 186.283 244.399 1.00 49.72  ? 304 PHE   A CD2   1 
ATOM   2862 C CE1   . PHE   D 2 292 ? 238.018 187.154 247.003 1.00 49.78  ? 304 PHE   A CE1   1 
ATOM   2863 C CE2   . PHE   D 2 292 ? 238.021 187.629 244.675 1.00 49.90  ? 304 PHE   A CE2   1 
ATOM   2864 C CZ    . PHE   D 2 292 ? 238.000 188.065 245.977 1.00 46.66  ? 304 PHE   A CZ    1 
ATOM   2865 N N     . ARG   D 2 293 ? 239.060 180.968 244.615 1.00 49.53  ? 305 ARG   A N     1 
ATOM   2866 C CA    . ARG   D 2 293 ? 238.973 179.531 244.828 1.00 49.82  ? 305 ARG   A CA    1 
ATOM   2867 C C     . ARG   D 2 293 ? 240.327 178.940 245.189 1.00 48.99  ? 305 ARG   A C     1 
ATOM   2868 O O     . ARG   D 2 293 ? 240.402 178.013 246.002 1.00 48.85  ? 305 ARG   A O     1 
ATOM   2869 C CB    . ARG   D 2 293 ? 238.411 178.866 243.572 1.00 51.29  ? 305 ARG   A CB    1 
ATOM   2870 C CG    . ARG   D 2 293 ? 238.207 177.373 243.679 1.00 55.84  ? 305 ARG   A CG    1 
ATOM   2871 C CD    . ARG   D 2 293 ? 237.326 176.875 242.551 1.00 51.87  ? 305 ARG   A CD    1 
ATOM   2872 N NE    . ARG   D 2 293 ? 237.845 177.263 241.246 1.00 51.07  ? 305 ARG   A NE    1 
ATOM   2873 C CZ    . ARG   D 2 293 ? 237.092 177.662 240.231 1.00 57.04  ? 305 ARG   A CZ    1 
ATOM   2874 N NH1   . ARG   D 2 293 ? 235.778 177.745 240.338 1.00 59.92  ? 305 ARG   A NH1   1 
ATOM   2875 N NH2   . ARG   D 2 293 ? 237.673 177.989 239.082 1.00 60.49  ? 305 ARG   A NH2   1 
ATOM   2876 N N     . LEU   D 2 294 ? 241.401 179.458 244.594 1.00 50.50  ? 306 LEU   A N     1 
ATOM   2877 C CA    . LEU   D 2 294 ? 242.736 178.983 244.933 1.00 52.03  ? 306 LEU   A CA    1 
ATOM   2878 C C     . LEU   D 2 294 ? 243.116 179.369 246.356 1.00 50.51  ? 306 LEU   A C     1 
ATOM   2879 O O     . LEU   D 2 294 ? 243.734 178.577 247.077 1.00 50.29  ? 306 LEU   A O     1 
ATOM   2880 C CB    . LEU   D 2 294 ? 243.750 179.540 243.936 1.00 51.62  ? 306 LEU   A CB    1 
ATOM   2881 C CG    . LEU   D 2 294 ? 245.123 178.880 243.938 1.00 53.10  ? 306 LEU   A CG    1 
ATOM   2882 C CD1   . LEU   D 2 294 ? 244.977 177.394 243.701 1.00 57.09  ? 306 LEU   A CD1   1 
ATOM   2883 C CD2   . LEU   D 2 294 ? 246.009 179.507 242.884 1.00 52.99  ? 306 LEU   A CD2   1 
ATOM   2884 N N     . LEU   D 2 295 ? 242.756 180.582 246.777 1.00 50.13  ? 307 LEU   A N     1 
ATOM   2885 C CA    . LEU   D 2 295 ? 243.148 181.059 248.097 1.00 48.81  ? 307 LEU   A CA    1 
ATOM   2886 C C     . LEU   D 2 295 ? 242.338 180.403 249.206 1.00 51.71  ? 307 LEU   A C     1 
ATOM   2887 O O     . LEU   D 2 295 ? 242.834 180.267 250.330 1.00 53.82  ? 307 LEU   A O     1 
ATOM   2888 C CB    . LEU   D 2 295 ? 243.000 182.578 248.168 1.00 49.24  ? 307 LEU   A CB    1 
ATOM   2889 C CG    . LEU   D 2 295 ? 244.205 183.397 247.713 1.00 49.14  ? 307 LEU   A CG    1 
ATOM   2890 C CD1   . LEU   D 2 295 ? 244.000 184.863 248.032 1.00 51.52  ? 307 LEU   A CD1   1 
ATOM   2891 C CD2   . LEU   D 2 295 ? 245.471 182.880 248.362 1.00 48.79  ? 307 LEU   A CD2   1 
ATOM   2892 N N     . GLN   D 2 296 ? 241.098 180.000 248.922 1.00 53.09  ? 308 GLN   A N     1 
ATOM   2893 C CA    . GLN   D 2 296 ? 240.262 179.431 249.975 1.00 53.65  ? 308 GLN   A CA    1 
ATOM   2894 C C     . GLN   D 2 296 ? 240.836 178.125 250.515 1.00 53.24  ? 308 GLN   A C     1 
ATOM   2895 O O     . GLN   D 2 296 ? 240.842 177.906 251.731 1.00 55.58  ? 308 GLN   A O     1 
ATOM   2896 C CB    . GLN   D 2 296 ? 238.839 179.223 249.463 1.00 51.17  ? 308 GLN   A CB    1 
ATOM   2897 C CG    . GLN   D 2 296 ? 238.026 180.500 249.406 1.00 49.72  ? 308 GLN   A CG    1 
ATOM   2898 C CD    . GLN   D 2 296 ? 237.162 180.687 250.631 1.00 52.57  ? 308 GLN   A CD    1 
ATOM   2899 O OE1   . GLN   D 2 296 ? 236.713 179.720 251.239 1.00 52.66  ? 308 GLN   A OE1   1 
ATOM   2900 N NE2   . GLN   D 2 296 ? 236.926 181.937 251.001 1.00 59.53  ? 308 GLN   A NE2   1 
ATOM   2901 N N     . ASN   D 2 297 ? 241.325 177.246 249.641 1.00 51.05  ? 309 ASN   A N     1 
ATOM   2902 C CA    . ASN   D 2 297 ? 241.822 175.941 250.062 1.00 54.87  ? 309 ASN   A CA    1 
ATOM   2903 C C     . ASN   D 2 297 ? 243.346 175.869 250.082 1.00 53.51  ? 309 ASN   A C     1 
ATOM   2904 O O     . ASN   D 2 297 ? 243.917 174.787 249.914 1.00 57.21  ? 309 ASN   A O     1 
ATOM   2905 C CB    . ASN   D 2 297 ? 241.247 174.834 249.178 1.00 54.40  ? 309 ASN   A CB    1 
ATOM   2906 C CG    . ASN   D 2 297 ? 241.486 175.072 247.704 1.00 55.08  ? 309 ASN   A CG    1 
ATOM   2907 O OD1   . ASN   D 2 297 ? 242.619 175.263 247.269 1.00 60.18  ? 309 ASN   A OD1   1 
ATOM   2908 N ND2   . ASN   D 2 297 ? 240.415 175.050 246.923 1.00 55.65  ? 309 ASN   A ND2   1 
ATOM   2909 N N     . SER   D 2 298 ? 244.018 176.995 250.293 1.00 50.63  ? 310 SER   A N     1 
ATOM   2910 C CA    . SER   D 2 298 ? 245.471 177.043 250.350 1.00 52.92  ? 310 SER   A CA    1 
ATOM   2911 C C     . SER   D 2 298 ? 245.919 177.468 251.739 1.00 53.11  ? 310 SER   A C     1 
ATOM   2912 O O     . SER   D 2 298 ? 245.298 178.333 252.363 1.00 56.41  ? 310 SER   A O     1 
ATOM   2913 C CB    . SER   D 2 298 ? 246.031 178.011 249.310 1.00 53.73  ? 310 SER   A CB    1 
ATOM   2914 O OG    . SER   D 2 298 ? 246.000 179.339 249.800 1.00 51.41  ? 310 SER   A OG    1 
ATOM   2915 N N     . GLN   D 2 299 ? 247.000 176.863 252.220 1.00 50.98  ? 311 GLN   A N     1 
ATOM   2916 C CA    . GLN   D 2 299 ? 247.573 177.198 253.517 1.00 52.80  ? 311 GLN   A CA    1 
ATOM   2917 C C     . GLN   D 2 299 ? 248.935 177.843 253.307 1.00 51.71  ? 311 GLN   A C     1 
ATOM   2918 O O     . GLN   D 2 299 ? 249.806 177.268 252.647 1.00 52.28  ? 311 GLN   A O     1 
ATOM   2919 C CB    . GLN   D 2 299 ? 247.688 175.964 254.411 1.00 55.07  ? 311 GLN   A CB    1 
ATOM   2920 C CG    . GLN   D 2 299 ? 248.237 174.734 253.730 1.00 54.78  ? 311 GLN   A CG    1 
ATOM   2921 C CD    . GLN   D 2 299 ? 248.436 173.592 254.698 1.00 59.87  ? 311 GLN   A CD    1 
ATOM   2922 O OE1   . GLN   D 2 299 ? 248.085 173.693 255.871 1.00 59.97  ? 311 GLN   A OE1   1 
ATOM   2923 N NE2   . GLN   D 2 299 ? 249.001 172.496 254.212 1.00 67.09  ? 311 GLN   A NE2   1 
ATOM   2924 N N     . VAL   D 2 300 ? 249.112 179.035 253.867 1.00 53.05  ? 312 VAL   A N     1 
ATOM   2925 C CA    . VAL   D 2 300 ? 250.343 179.802 253.744 1.00 53.41  ? 312 VAL   A CA    1 
ATOM   2926 C C     . VAL   D 2 300 ? 250.807 180.163 255.146 1.00 53.35  ? 312 VAL   A C     1 
ATOM   2927 O O     . VAL   D 2 300 ? 249.987 180.487 256.010 1.00 54.32  ? 312 VAL   A O     1 
ATOM   2928 C CB    . VAL   D 2 300 ? 250.143 181.068 252.887 1.00 51.28  ? 312 VAL   A CB    1 
ATOM   2929 C CG1   . VAL   D 2 300 ? 251.371 181.957 252.938 1.00 50.37  ? 312 VAL   A CG1   1 
ATOM   2930 C CG2   . VAL   D 2 300 ? 249.825 180.692 251.455 1.00 48.12  ? 312 VAL   A CG2   1 
ATOM   2931 N N     . TYR   D 2 301 ? 252.109 180.071 255.382 1.00 52.48  ? 313 TYR   A N     1 
ATOM   2932 C CA    . TYR   D 2 301 ? 252.696 180.417 256.665 1.00 52.25  ? 313 TYR   A CA    1 
ATOM   2933 C C     . TYR   D 2 301 ? 253.561 181.661 256.524 1.00 52.39  ? 313 TYR   A C     1 
ATOM   2934 O O     . TYR   D 2 301 ? 254.056 181.983 255.442 1.00 54.72  ? 313 TYR   A O     1 
ATOM   2935 C CB    . TYR   D 2 301 ? 253.518 179.251 257.220 1.00 51.36  ? 313 TYR   A CB    1 
ATOM   2936 C CG    . TYR   D 2 301 ? 252.724 177.977 257.358 1.00 53.17  ? 313 TYR   A CG    1 
ATOM   2937 C CD1   . TYR   D 2 301 ? 252.000 177.711 258.510 1.00 52.40  ? 313 TYR   A CD1   1 
ATOM   2938 C CD2   . TYR   D 2 301 ? 252.690 177.043 256.335 1.00 55.63  ? 313 TYR   A CD2   1 
ATOM   2939 C CE1   . TYR   D 2 301 ? 251.268 176.551 258.640 1.00 53.18  ? 313 TYR   A CE1   1 
ATOM   2940 C CE2   . TYR   D 2 301 ? 251.962 175.880 256.457 1.00 54.34  ? 313 TYR   A CE2   1 
ATOM   2941 C CZ    . TYR   D 2 301 ? 251.253 175.640 257.610 1.00 54.62  ? 313 TYR   A CZ    1 
ATOM   2942 O OH    . TYR   D 2 301 ? 250.526 174.482 257.736 1.00 60.04  ? 313 TYR   A OH    1 
ATOM   2943 N N     . SER   D 2 302 ? 253.728 182.370 257.636 1.00 51.49  ? 314 SER   A N     1 
ATOM   2944 C CA    . SER   D 2 302 ? 254.493 183.606 257.629 1.00 50.05  ? 314 SER   A CA    1 
ATOM   2945 C C     . SER   D 2 302 ? 255.214 183.757 258.957 1.00 50.38  ? 314 SER   A C     1 
ATOM   2946 O O     . SER   D 2 302 ? 254.889 183.094 259.945 1.00 52.63  ? 314 SER   A O     1 
ATOM   2947 C CB    . SER   D 2 302 ? 253.605 184.824 257.367 1.00 52.27  ? 314 SER   A CB    1 
ATOM   2948 O OG    . SER   D 2 302 ? 254.222 186.005 257.843 1.00 54.46  ? 314 SER   A OG    1 
ATOM   2949 N N     . LEU   D 2 303 ? 256.204 184.640 258.962 1.00 49.27  ? 315 LEU   A N     1 
ATOM   2950 C CA    . LEU   D 2 303 ? 257.027 184.893 260.135 1.00 50.75  ? 315 LEU   A CA    1 
ATOM   2951 C C     . LEU   D 2 303 ? 256.484 186.108 260.871 1.00 51.96  ? 315 LEU   A C     1 
ATOM   2952 O O     . LEU   D 2 303 ? 256.398 187.201 260.301 1.00 55.37  ? 315 LEU   A O     1 
ATOM   2953 C CB    . LEU   D 2 303 ? 258.486 185.108 259.739 1.00 51.22  ? 315 LEU   A CB    1 
ATOM   2954 C CG    . LEU   D 2 303 ? 259.188 183.874 259.181 1.00 48.05  ? 315 LEU   A CG    1 
ATOM   2955 C CD1   . LEU   D 2 303 ? 260.639 184.179 258.890 1.00 52.26  ? 315 LEU   A CD1   1 
ATOM   2956 C CD2   . LEU   D 2 303 ? 259.068 182.720 260.152 1.00 49.71  ? 315 LEU   A CD2   1 
ATOM   2957 N N     . ILE   D 2 304 ? 256.124 185.912 262.132 1.00 51.63  ? 316 ILE   A N     1 
ATOM   2958 C CA    . ILE   D 2 304 ? 255.582 186.956 262.986 1.00 50.85  ? 316 ILE   A CA    1 
ATOM   2959 C C     . ILE   D 2 304 ? 256.669 187.369 263.965 1.00 53.06  ? 316 ILE   A C     1 
ATOM   2960 O O     . ILE   D 2 304 ? 257.165 186.544 264.745 1.00 55.65  ? 316 ILE   A O     1 
ATOM   2961 C CB    . ILE   D 2 304 ? 254.321 186.483 263.723 1.00 51.33  ? 316 ILE   A CB    1 
ATOM   2962 C CG1   . ILE   D 2 304 ? 253.160 186.341 262.743 1.00 53.32  ? 316 ILE   A CG1   1 
ATOM   2963 C CG2   . ILE   D 2 304 ? 253.954 187.449 264.829 1.00 54.62  ? 316 ILE   A CG2   1 
ATOM   2964 C CD1   . ILE   D 2 304 ? 252.616 187.659 262.259 1.00 56.63  ? 316 ILE   A CD1   1 
ATOM   2965 N N     . ARG   D 2 305 ? 257.052 188.637 263.905 1.00 51.71  ? 317 ARG   A N     1 
ATOM   2966 C CA    . ARG   D 2 305 ? 257.969 189.195 264.877 1.00 53.59  ? 317 ARG   A CA    1 
ATOM   2967 C C     . ARG   D 2 305 ? 257.274 189.288 266.234 1.00 56.93  ? 317 ARG   A C     1 
ATOM   2968 O O     . ARG   D 2 305 ? 256.045 189.365 266.300 1.00 60.42  ? 317 ARG   A O     1 
ATOM   2969 C CB    . ARG   D 2 305 ? 258.438 190.571 264.415 1.00 50.30  ? 317 ARG   A CB    1 
ATOM   2970 C CG    . ARG   D 2 305 ? 258.552 190.666 262.907 1.00 50.86  ? 317 ARG   A CG    1 
ATOM   2971 C CD    . ARG   D 2 305 ? 259.043 192.015 262.438 1.00 45.02  ? 317 ARG   A CD    1 
ATOM   2972 N NE    . ARG   D 2 305 ? 258.573 192.297 261.088 1.00 46.32  ? 317 ARG   A NE    1 
ATOM   2973 C CZ    . ARG   D 2 305 ? 259.354 192.678 260.087 1.00 48.47  ? 317 ARG   A CZ    1 
ATOM   2974 N NH1   . ARG   D 2 305 ? 260.654 192.843 260.249 1.00 52.31  ? 317 ARG   A NH1   1 
ATOM   2975 N NH2   . ARG   D 2 305 ? 258.815 192.898 258.892 1.00 50.47  ? 317 ARG   A NH2   1 
ATOM   2976 N N     . PRO   D 2 306 ? 258.031 189.260 267.330 1.00 56.77  ? 318 PRO   A N     1 
ATOM   2977 C CA    . PRO   D 2 306 ? 257.397 189.300 268.652 1.00 58.16  ? 318 PRO   A CA    1 
ATOM   2978 C C     . PRO   D 2 306 ? 256.553 190.554 268.816 1.00 62.81  ? 318 PRO   A C     1 
ATOM   2979 O O     . PRO   D 2 306 ? 256.913 191.634 268.345 1.00 64.95  ? 318 PRO   A O     1 
ATOM   2980 C CB    . PRO   D 2 306 ? 258.587 189.283 269.619 1.00 52.68  ? 318 PRO   A CB    1 
ATOM   2981 C CG    . PRO   D 2 306 ? 259.741 189.755 268.813 1.00 55.60  ? 318 PRO   A CG    1 
ATOM   2982 C CD    . PRO   D 2 306 ? 259.499 189.238 267.432 1.00 57.04  ? 318 PRO   A CD    1 
ATOM   2983 N N     . ASN   D 2 307 ? 255.408 190.389 269.478 1.00 58.93  ? 319 ASN   A N     1 
ATOM   2984 C CA    . ASN   D 2 307 ? 254.437 191.462 269.683 1.00 60.44  ? 319 ASN   A CA    1 
ATOM   2985 C C     . ASN   D 2 307 ? 253.917 191.993 268.346 1.00 57.11  ? 319 ASN   A C     1 
ATOM   2986 O O     . ASN   D 2 307 ? 254.078 193.163 267.998 1.00 58.03  ? 319 ASN   A O     1 
ATOM   2987 C CB    . ASN   D 2 307 ? 255.029 192.586 270.539 1.00 59.87  ? 319 ASN   A CB    1 
ATOM   2988 C CG    . ASN   D 2 307 ? 255.007 192.262 272.015 1.00 67.23  ? 319 ASN   A CG    1 
ATOM   2989 O OD1   . ASN   D 2 307 ? 254.048 191.680 272.519 1.00 67.30  ? 319 ASN   A OD1   1 
ATOM   2990 N ND2   . ASN   D 2 307 ? 256.068 192.633 272.719 1.00 71.40  ? 319 ASN   A ND2   1 
ATOM   2991 N N     . GLU   D 2 308 ? 253.291 191.092 267.594 1.00 53.94  ? 320 GLU   A N     1 
ATOM   2992 C CA    . GLU   D 2 308 ? 252.590 191.440 266.370 1.00 53.90  ? 320 GLU   A CA    1 
ATOM   2993 C C     . GLU   D 2 308 ? 251.292 190.650 266.314 1.00 59.64  ? 320 GLU   A C     1 
ATOM   2994 O O     . GLU   D 2 308 ? 251.153 189.603 266.948 1.00 67.63  ? 320 GLU   A O     1 
ATOM   2995 C CB    . GLU   D 2 308 ? 253.436 191.162 265.123 1.00 53.32  ? 320 GLU   A CB    1 
ATOM   2996 C CG    . GLU   D 2 308 ? 254.230 192.359 264.642 1.00 51.47  ? 320 GLU   A CG    1 
ATOM   2997 C CD    . GLU   D 2 308 ? 254.693 192.211 263.212 1.00 53.88  ? 320 GLU   A CD    1 
ATOM   2998 O OE1   . GLU   D 2 308 ? 254.486 191.128 262.631 1.00 55.56  ? 320 GLU   A OE1   1 
ATOM   2999 O OE2   . GLU   D 2 308 ? 255.263 193.176 262.669 1.00 58.74  ? 320 GLU   A OE2   1 
ATOM   3000 N N     . ASN   D 2 309 ? 250.335 191.167 265.551 1.00 56.95  ? 321 ASN   A N     1 
ATOM   3001 C CA    . ASN   D 2 309 ? 249.041 190.517 265.429 1.00 55.54  ? 321 ASN   A CA    1 
ATOM   3002 C C     . ASN   D 2 309 ? 249.000 189.725 264.133 1.00 53.28  ? 321 ASN   A C     1 
ATOM   3003 O O     . ASN   D 2 309 ? 249.017 190.330 263.050 1.00 52.68  ? 321 ASN   A O     1 
ATOM   3004 C CB    . ASN   D 2 309 ? 247.916 191.547 265.461 1.00 55.31  ? 321 ASN   A CB    1 
ATOM   3005 C CG    . ASN   D 2 309 ? 246.622 190.979 266.000 1.00 57.66  ? 321 ASN   A CG    1 
ATOM   3006 O OD1   . ASN   D 2 309 ? 246.507 189.778 266.230 1.00 63.04  ? 321 ASN   A OD1   1 
ATOM   3007 N ND2   . ASN   D 2 309 ? 245.638 191.843 266.204 1.00 59.82  ? 321 ASN   A ND2   1 
ATOM   3008 N N     . PRO   D 2 310 ? 248.958 188.392 264.182 1.00 54.20  ? 322 PRO   A N     1 
ATOM   3009 C CA    . PRO   D 2 310 ? 248.903 187.618 262.933 1.00 54.78  ? 322 PRO   A CA    1 
ATOM   3010 C C     . PRO   D 2 310 ? 247.689 187.933 262.080 1.00 54.49  ? 322 PRO   A C     1 
ATOM   3011 O O     . PRO   D 2 310 ? 247.760 187.812 260.852 1.00 54.49  ? 322 PRO   A O     1 
ATOM   3012 C CB    . PRO   D 2 310 ? 248.895 186.162 263.423 1.00 54.43  ? 322 PRO   A CB    1 
ATOM   3013 C CG    . PRO   D 2 310 ? 248.484 186.228 264.854 1.00 49.56  ? 322 PRO   A CG    1 
ATOM   3014 C CD    . PRO   D 2 310 ? 249.000 187.526 265.371 1.00 52.21  ? 322 PRO   A CD    1 
ATOM   3015 N N     . ALA   D 2 311 ? 246.575 188.335 262.695 1.00 52.51  ? 323 ALA   A N     1 
ATOM   3016 C CA    . ALA   D 2 311 ? 245.394 188.711 261.924 1.00 51.82  ? 323 ALA   A CA    1 
ATOM   3017 C C     . ALA   D 2 311 ? 245.672 189.923 261.043 1.00 51.20  ? 323 ALA   A C     1 
ATOM   3018 O O     . ALA   D 2 311 ? 245.232 189.978 259.889 1.00 49.00  ? 323 ALA   A O     1 
ATOM   3019 C CB    . ALA   D 2 311 ? 244.223 188.987 262.864 1.00 49.52  ? 323 ALA   A CB    1 
ATOM   3020 N N     . HIS   D 2 312 ? 246.401 190.906 261.571 1.00 51.66  ? 324 HIS   A N     1 
ATOM   3021 C CA    . HIS   D 2 312 ? 246.732 192.087 260.782 1.00 51.84  ? 324 HIS   A CA    1 
ATOM   3022 C C     . HIS   D 2 312 ? 247.669 191.745 259.627 1.00 51.61  ? 324 HIS   A C     1 
ATOM   3023 O O     . HIS   D 2 312 ? 247.503 192.257 258.514 1.00 55.27  ? 324 HIS   A O     1 
ATOM   3024 C CB    . HIS   D 2 312 ? 247.338 193.157 261.688 1.00 52.25  ? 324 HIS   A CB    1 
ATOM   3025 C CG    . HIS   D 2 312 ? 246.374 193.710 262.691 1.00 54.76  ? 324 HIS   A CG    1 
ATOM   3026 N ND1   . HIS   D 2 312 ? 246.777 194.256 263.890 1.00 57.74  ? 324 HIS   A ND1   1 
ATOM   3027 C CD2   . HIS   D 2 312 ? 245.023 193.798 262.674 1.00 54.48  ? 324 HIS   A CD2   1 
ATOM   3028 C CE1   . HIS   D 2 312 ? 245.716 194.658 264.568 1.00 55.19  ? 324 HIS   A CE1   1 
ATOM   3029 N NE2   . HIS   D 2 312 ? 244.639 194.392 263.852 1.00 51.68  ? 324 HIS   A NE2   1 
ATOM   3030 N N     . LYS   D 2 313 ? 248.653 190.877 259.867 1.00 49.35  ? 325 LYS   A N     1 
ATOM   3031 C CA    . LYS   D 2 313 ? 249.536 190.451 258.785 1.00 51.94  ? 325 LYS   A CA    1 
ATOM   3032 C C     . LYS   D 2 313 ? 248.768 189.687 257.713 1.00 50.81  ? 325 LYS   A C     1 
ATOM   3033 O O     . LYS   D 2 313 ? 249.004 189.875 256.512 1.00 49.35  ? 325 LYS   A O     1 
ATOM   3034 C CB    . LYS   D 2 313 ? 250.675 189.597 259.341 1.00 50.71  ? 325 LYS   A CB    1 
ATOM   3035 C CG    . LYS   D 2 313 ? 251.661 189.128 258.290 1.00 52.66  ? 325 LYS   A CG    1 
ATOM   3036 C CD    . LYS   D 2 313 ? 253.033 188.894 258.885 1.00 51.28  ? 325 LYS   A CD    1 
ATOM   3037 C CE    . LYS   D 2 313 ? 253.730 190.199 259.198 1.00 46.23  ? 325 LYS   A CE    1 
ATOM   3038 N NZ    . LYS   D 2 313 ? 255.190 190.000 259.377 1.00 48.88  ? 325 LYS   A NZ    1 
ATOM   3039 N N     . SER   D 2 314 ? 247.846 188.817 258.128 1.00 49.79  ? 326 SER   A N     1 
ATOM   3040 C CA    . SER   D 2 314 ? 247.032 188.084 257.165 1.00 50.50  ? 326 SER   A CA    1 
ATOM   3041 C C     . SER   D 2 314 ? 246.158 189.030 256.353 1.00 49.63  ? 326 SER   A C     1 
ATOM   3042 O O     . SER   D 2 314 ? 246.000 188.852 255.140 1.00 50.02  ? 326 SER   A O     1 
ATOM   3043 C CB    . SER   D 2 314 ? 246.179 187.040 257.885 1.00 49.22  ? 326 SER   A CB    1 
ATOM   3044 O OG    . SER   D 2 314 ? 245.345 187.643 258.853 1.00 56.73  ? 326 SER   A OG    1 
ATOM   3045 N N     . GLN   D 2 315 ? 245.588 190.046 257.003 1.00 49.33  ? 327 GLN   A N     1 
ATOM   3046 C CA    . GLN   D 2 315 ? 244.802 191.036 256.274 1.00 49.84  ? 327 GLN   A CA    1 
ATOM   3047 C C     . GLN   D 2 315 ? 245.663 191.788 255.269 1.00 48.02  ? 327 GLN   A C     1 
ATOM   3048 O O     . GLN   D 2 315 ? 245.231 192.048 254.140 1.00 49.96  ? 327 GLN   A O     1 
ATOM   3049 C CB    . GLN   D 2 315 ? 244.147 192.009 257.250 1.00 48.14  ? 327 GLN   A CB    1 
ATOM   3050 C CG    . GLN   D 2 315 ? 243.576 193.241 256.584 1.00 46.60  ? 327 GLN   A CG    1 
ATOM   3051 C CD    . GLN   D 2 315 ? 243.499 194.419 257.520 1.00 48.90  ? 327 GLN   A CD    1 
ATOM   3052 O OE1   . GLN   D 2 315 ? 243.000 194.306 258.637 1.00 51.28  ? 327 GLN   A OE1   1 
ATOM   3053 N NE2   . GLN   D 2 315 ? 243.995 195.563 257.070 1.00 50.01  ? 327 GLN   A NE2   1 
ATOM   3054 N N     . LEU   D 2 316 ? 246.887 192.144 255.664 1.00 48.40  ? 328 LEU   A N     1 
ATOM   3055 C CA    . LEU   D 2 316 ? 247.792 192.828 254.748 1.00 50.13  ? 328 LEU   A CA    1 
ATOM   3056 C C     . LEU   D 2 316 ? 248.100 191.964 253.532 1.00 49.13  ? 328 LEU   A C     1 
ATOM   3057 O O     . LEU   D 2 316 ? 248.075 192.447 252.393 1.00 50.72  ? 328 LEU   A O     1 
ATOM   3058 C CB    . LEU   D 2 316 ? 249.080 193.202 255.480 1.00 48.75  ? 328 LEU   A CB    1 
ATOM   3059 C CG    . LEU   D 2 316 ? 250.056 194.137 254.772 1.00 46.56  ? 328 LEU   A CG    1 
ATOM   3060 C CD1   . LEU   D 2 316 ? 250.505 195.232 255.718 1.00 44.89  ? 328 LEU   A CD1   1 
ATOM   3061 C CD2   . LEU   D 2 316 ? 251.249 193.360 254.256 1.00 51.63  ? 328 LEU   A CD2   1 
ATOM   3062 N N     . VAL   D 2 317 ? 248.381 190.680 253.755 1.00 48.18  ? 329 VAL   A N     1 
ATOM   3063 C CA    . VAL   D 2 317 ? 248.700 189.789 252.644 1.00 47.02  ? 329 VAL   A CA    1 
ATOM   3064 C C     . VAL   D 2 317 ? 247.483 189.593 251.748 1.00 46.11  ? 329 VAL   A C     1 
ATOM   3065 O O     . VAL   D 2 317 ? 247.606 189.514 250.524 1.00 46.87  ? 329 VAL   A O     1 
ATOM   3066 C CB    . VAL   D 2 317 ? 249.249 188.451 253.168 1.00 48.44  ? 329 VAL   A CB    1 
ATOM   3067 C CG1   . VAL   D 2 317 ? 249.451 187.473 252.026 1.00 45.68  ? 329 VAL   A CG1   1 
ATOM   3068 C CG2   . VAL   D 2 317 ? 250.555 188.674 253.903 1.00 50.97  ? 329 VAL   A CG2   1 
ATOM   3069 N N     . TRP   D 2 318 ? 246.290 189.515 252.341 1.00 45.38  ? 330 TRP   A N     1 
ATOM   3070 C CA    . TRP   D 2 318 ? 245.062 189.407 251.558 1.00 44.18  ? 330 TRP   A CA    1 
ATOM   3071 C C     . TRP   D 2 318 ? 244.868 190.630 250.667 1.00 46.45  ? 330 TRP   A C     1 
ATOM   3072 O O     . TRP   D 2 318 ? 244.584 190.510 249.464 1.00 48.49  ? 330 TRP   A O     1 
ATOM   3073 C CB    . TRP   D 2 318 ? 243.881 189.227 252.514 1.00 44.88  ? 330 TRP   A CB    1 
ATOM   3074 C CG    . TRP   D 2 318 ? 242.567 189.004 251.861 1.00 46.43  ? 330 TRP   A CG    1 
ATOM   3075 C CD1   . TRP   D 2 318 ? 242.016 187.808 251.520 1.00 48.95  ? 330 TRP   A CD1   1 
ATOM   3076 C CD2   . TRP   D 2 318 ? 241.616 190.005 251.490 1.00 45.02  ? 330 TRP   A CD2   1 
ATOM   3077 N NE1   . TRP   D 2 318 ? 240.786 188.000 250.946 1.00 49.52  ? 330 TRP   A NE1   1 
ATOM   3078 C CE2   . TRP   D 2 318 ? 240.517 189.341 250.917 1.00 47.63  ? 330 TRP   A CE2   1 
ATOM   3079 C CE3   . TRP   D 2 318 ? 241.591 191.398 251.580 1.00 45.11  ? 330 TRP   A CE3   1 
ATOM   3080 C CZ2   . TRP   D 2 318 ? 239.406 190.023 250.435 1.00 49.91  ? 330 TRP   A CZ2   1 
ATOM   3081 C CZ3   . TRP   D 2 318 ? 240.489 192.071 251.101 1.00 45.84  ? 330 TRP   A CZ3   1 
ATOM   3082 C CH2   . TRP   D 2 318 ? 239.411 191.384 250.537 1.00 49.40  ? 330 TRP   A CH2   1 
ATOM   3083 N N     . MET   D 2 319 ? 245.039 191.821 251.245 1.00 47.93  ? 331 MET   A N     1 
ATOM   3084 C CA    . MET   D 2 319 ? 244.904 193.058 250.484 1.00 48.98  ? 331 MET   A CA    1 
ATOM   3085 C C     . MET   D 2 319 ? 245.918 193.113 249.353 1.00 49.76  ? 331 MET   A C     1 
ATOM   3086 O O     . MET   D 2 319 ? 245.597 193.538 248.237 1.00 48.92  ? 331 MET   A O     1 
ATOM   3087 C CB    . MET   D 2 319 ? 245.079 194.256 251.416 1.00 45.65  ? 331 MET   A CB    1 
ATOM   3088 C CG    . MET   D 2 319 ? 243.982 194.406 252.447 1.00 47.89  ? 331 MET   A CG    1 
ATOM   3089 S SD    . MET   D 2 319 ? 244.071 195.957 253.356 1.00 61.42  ? 331 MET   A SD    1 
ATOM   3090 C CE    . MET   D 2 319 ? 244.009 197.135 252.021 1.00 49.72  ? 331 MET   A CE    1 
ATOM   3091 N N     . ALA   D 2 320 ? 247.154 192.695 249.629 1.00 48.96  ? 332 ALA   A N     1 
ATOM   3092 C CA    . ALA   D 2 320 ? 248.178 192.654 248.593 1.00 48.65  ? 332 ALA   A CA    1 
ATOM   3093 C C     . ALA   D 2 320 ? 247.814 191.670 247.491 1.00 48.90  ? 332 ALA   A C     1 
ATOM   3094 O O     . ALA   D 2 320 ? 248.000 191.958 246.303 1.00 49.37  ? 332 ALA   A O     1 
ATOM   3095 C CB    . ALA   D 2 320 ? 249.522 192.285 249.211 1.00 48.58  ? 332 ALA   A CB    1 
ATOM   3096 N N     . CYS   D 2 321 ? 247.302 190.497 247.868 1.00 50.27  ? 333 CYS   A N     1 
ATOM   3097 C CA    . CYS   D 2 321 ? 246.971 189.475 246.884 1.00 49.87  ? 333 CYS   A CA    1 
ATOM   3098 C C     . CYS   D 2 321 ? 245.887 189.958 245.937 1.00 50.69  ? 333 CYS   A C     1 
ATOM   3099 O O     . CYS   D 2 321 ? 245.978 189.753 244.722 1.00 53.32  ? 333 CYS   A O     1 
ATOM   3100 C CB    . CYS   D 2 321 ? 246.528 188.192 247.589 1.00 46.27  ? 333 CYS   A CB    1 
ATOM   3101 S SG    . CYS   D 2 321 ? 247.870 187.184 248.243 1.00 59.31  ? 333 CYS   A SG    1 
ATOM   3102 N N     . HIS   D 2 322 ? 244.858 190.612 246.468 1.00 49.37  ? 334 HIS   A N     1 
ATOM   3103 C CA    . HIS   D 2 322 ? 243.753 191.061 245.634 1.00 48.61  ? 334 HIS   A CA    1 
ATOM   3104 C C     . HIS   D 2 322 ? 243.927 192.489 245.129 1.00 52.20  ? 334 HIS   A C     1 
ATOM   3105 O O     . HIS   D 2 322 ? 243.019 193.014 244.479 1.00 52.06  ? 334 HIS   A O     1 
ATOM   3106 C CB    . HIS   D 2 322 ? 242.436 190.917 246.394 1.00 47.18  ? 334 HIS   A CB    1 
ATOM   3107 C CG    . HIS   D 2 322 ? 242.070 189.496 246.682 1.00 48.72  ? 334 HIS   A CG    1 
ATOM   3108 N ND1   . HIS   D 2 322 ? 241.761 188.593 245.689 1.00 49.19  ? 334 HIS   A ND1   1 
ATOM   3109 C CD2   . HIS   D 2 322 ? 241.987 188.814 247.848 1.00 49.36  ? 334 HIS   A CD2   1 
ATOM   3110 C CE1   . HIS   D 2 322 ? 241.491 187.420 246.231 1.00 49.85  ? 334 HIS   A CE1   1 
ATOM   3111 N NE2   . HIS   D 2 322 ? 241.622 187.527 247.540 1.00 51.08  ? 334 HIS   A NE2   1 
ATOM   3112 N N     . SER   D 2 323 ? 245.074 193.114 245.400 1.00 57.29  ? 335 SER   A N     1 
ATOM   3113 C CA    . SER   D 2 323 ? 245.361 194.486 244.974 1.00 54.56  ? 335 SER   A CA    1 
ATOM   3114 C C     . SER   D 2 323 ? 244.288 195.453 245.464 1.00 52.33  ? 335 SER   A C     1 
ATOM   3115 O O     . SER   D 2 323 ? 243.891 196.380 244.757 1.00 58.60  ? 335 SER   A O     1 
ATOM   3116 C CB    . SER   D 2 323 ? 245.523 194.580 243.455 1.00 50.04  ? 335 SER   A CB    1 
ATOM   3117 O OG    . SER   D 2 323 ? 244.277 194.448 242.801 1.00 55.70  ? 335 SER   A OG    1 
ATOM   3118 N N     . ALA   D 2 324 ? 243.819 195.238 246.691 1.00 49.02  ? 336 ALA   A N     1 
ATOM   3119 C CA    . ALA   D 2 324 ? 242.778 196.061 247.290 1.00 51.00  ? 336 ALA   A CA    1 
ATOM   3120 C C     . ALA   D 2 324 ? 243.344 197.113 248.233 1.00 52.21  ? 336 ALA   A C     1 
ATOM   3121 O O     . ALA   D 2 324 ? 242.659 197.536 249.169 1.00 57.65  ? 336 ALA   A O     1 
ATOM   3122 C CB    . ALA   D 2 324 ? 241.769 195.181 248.026 1.00 47.17  ? 336 ALA   A CB    1 
ATOM   3123 N N     . ALA   D 2 325 ? 244.586 197.545 248.004 1.00 49.00  ? 337 ALA   A N     1 
ATOM   3124 C CA    . ALA   D 2 325 ? 245.223 198.485 248.920 1.00 51.41  ? 337 ALA   A CA    1 
ATOM   3125 C C     . ALA   D 2 325 ? 244.478 199.812 248.965 1.00 53.19  ? 337 ALA   A C     1 
ATOM   3126 O O     . ALA   D 2 325 ? 244.255 200.372 250.043 1.00 55.24  ? 337 ALA   A O     1 
ATOM   3127 C CB    . ALA   D 2 325 ? 246.680 198.703 248.518 1.00 52.32  ? 337 ALA   A CB    1 
ATOM   3128 N N     . PHE   D 2 326 ? 244.076 200.324 247.805 1.00 52.12  ? 338 PHE   A N     1 
ATOM   3129 C CA    . PHE   D 2 326 ? 243.395 201.606 247.704 1.00 51.40  ? 338 PHE   A CA    1 
ATOM   3130 C C     . PHE   D 2 326 ? 241.887 201.444 247.596 1.00 53.94  ? 338 PHE   A C     1 
ATOM   3131 O O     . PHE   D 2 326 ? 241.192 202.372 247.173 1.00 59.48  ? 338 PHE   A O     1 
ATOM   3132 C CB    . PHE   D 2 326 ? 243.947 202.389 246.517 1.00 48.81  ? 338 PHE   A CB    1 
ATOM   3133 C CG    . PHE   D 2 326 ? 245.440 202.482 246.513 1.00 50.51  ? 338 PHE   A CG    1 
ATOM   3134 C CD1   . PHE   D 2 326 ? 246.106 203.110 247.548 1.00 50.40  ? 338 PHE   A CD1   1 
ATOM   3135 C CD2   . PHE   D 2 326 ? 246.181 201.923 245.491 1.00 52.61  ? 338 PHE   A CD2   1 
ATOM   3136 C CE1   . PHE   D 2 326 ? 247.479 203.190 247.556 1.00 51.16  ? 338 PHE   A CE1   1 
ATOM   3137 C CE2   . PHE   D 2 326 ? 247.555 202.001 245.495 1.00 55.14  ? 338 PHE   A CE2   1 
ATOM   3138 C CZ    . PHE   D 2 326 ? 248.204 202.637 246.528 1.00 52.39  ? 338 PHE   A CZ    1 
ATOM   3139 N N     . GLU   D 2 327 ? 241.379 200.277 247.965 1.00 52.62  ? 339 GLU   A N     1 
ATOM   3140 C CA    . GLU   D 2 327 ? 239.960 199.984 247.907 1.00 51.16  ? 339 GLU   A CA    1 
ATOM   3141 C C     . GLU   D 2 327 ? 239.239 200.595 249.101 1.00 52.06  ? 339 GLU   A C     1 
ATOM   3142 O O     . GLU   D 2 327 ? 239.838 200.864 250.145 1.00 57.12  ? 339 GLU   A O     1 
ATOM   3143 C CB    . GLU   D 2 327 ? 239.758 198.468 247.873 1.00 52.16  ? 339 GLU   A CB    1 
ATOM   3144 C CG    . GLU   D 2 327 ? 238.346 197.974 247.634 1.00 51.39  ? 339 GLU   A CG    1 
ATOM   3145 C CD    . GLU   D 2 327 ? 237.812 198.316 246.265 1.00 55.89  ? 339 GLU   A CD    1 
ATOM   3146 O OE1   . GLU   D 2 327 ? 238.556 198.877 245.439 1.00 67.32  ? 339 GLU   A OE1   1 
ATOM   3147 O OE2   . GLU   D 2 327 ? 236.641 197.994 246.004 1.00 54.39  ? 339 GLU   A OE2   1 
ATOM   3148 N N     . ASP   D 2 328 ? 237.943 200.832 248.929 1.00 48.44  ? 340 ASP   A N     1 
ATOM   3149 C CA    . ASP   D 2 328 ? 237.110 201.255 250.043 1.00 48.30  ? 340 ASP   A CA    1 
ATOM   3150 C C     . ASP   D 2 328 ? 237.137 200.195 251.135 1.00 49.46  ? 340 ASP   A C     1 
ATOM   3151 O O     . ASP   D 2 328 ? 237.000 199.000 250.863 1.00 49.19  ? 340 ASP   A O     1 
ATOM   3152 C CB    . ASP   D 2 328 ? 235.683 201.501 249.556 1.00 50.26  ? 340 ASP   A CB    1 
ATOM   3153 C CG    . ASP   D 2 328 ? 234.893 202.389 250.484 1.00 52.92  ? 340 ASP   A CG    1 
ATOM   3154 O OD1   . ASP   D 2 328 ? 235.300 202.546 251.651 1.00 56.66  ? 340 ASP   A OD1   1 
ATOM   3155 O OD2   . ASP   D 2 328 ? 233.862 202.937 250.043 1.00 55.33  ? 340 ASP   A OD2   1 
ATOM   3156 N N     . LEU   D 2 329 ? 237.340 200.636 252.376 1.00 53.26  ? 341 LEU   A N     1 
ATOM   3157 C CA    . LEU   D 2 329 ? 237.443 199.687 253.477 1.00 51.67  ? 341 LEU   A CA    1 
ATOM   3158 C C     . LEU   D 2 329 ? 236.133 198.948 253.702 1.00 49.10  ? 341 LEU   A C     1 
ATOM   3159 O O     . LEU   D 2 329 ? 236.144 197.788 254.121 1.00 47.03  ? 341 LEU   A O     1 
ATOM   3160 C CB    . LEU   D 2 329 ? 237.875 200.406 254.754 1.00 51.57  ? 341 LEU   A CB    1 
ATOM   3161 C CG    . LEU   D 2 329 ? 239.340 200.838 254.825 1.00 50.69  ? 341 LEU   A CG    1 
ATOM   3162 C CD1   . LEU   D 2 329 ? 239.776 201.000 256.267 1.00 54.31  ? 341 LEU   A CD1   1 
ATOM   3163 C CD2   . LEU   D 2 329 ? 240.230 199.846 254.104 1.00 46.05  ? 341 LEU   A CD2   1 
ATOM   3164 N N     . ARG   D 2 330 ? 235.002 199.595 253.418 1.00 51.30  ? 342 ARG   A N     1 
ATOM   3165 C CA    . ARG   D 2 330 ? 233.707 198.962 253.636 1.00 49.18  ? 342 ARG   A CA    1 
ATOM   3166 C C     . ARG   D 2 330 ? 233.494 197.789 252.686 1.00 48.44  ? 342 ARG   A C     1 
ATOM   3167 O O     . ARG   D 2 330 ? 233.078 196.705 253.109 1.00 47.03  ? 342 ARG   A O     1 
ATOM   3168 C CB    . ARG   D 2 330 ? 232.597 200.000 253.487 1.00 49.31  ? 342 ARG   A CB    1 
ATOM   3169 C CG    . ARG   D 2 330 ? 232.991 201.372 254.000 1.00 49.94  ? 342 ARG   A CG    1 
ATOM   3170 C CD    . ARG   D 2 330 ? 231.903 202.403 253.775 1.00 48.61  ? 342 ARG   A CD    1 
ATOM   3171 N NE    . ARG   D 2 330 ? 231.893 202.897 252.404 1.00 52.85  ? 342 ARG   A NE    1 
ATOM   3172 C CZ    . ARG   D 2 330 ? 230.919 203.627 251.880 1.00 52.81  ? 342 ARG   A CZ    1 
ATOM   3173 N NH1   . ARG   D 2 330 ? 229.873 204.000 252.596 1.00 50.48  ? 342 ARG   A NH1   1 
ATOM   3174 N NH2   . ARG   D 2 330 ? 231.001 203.997 250.606 1.00 52.79  ? 342 ARG   A NH2   1 
ATOM   3175 N N     . VAL   D 2 331 ? 233.784 197.977 251.397 1.00 50.26  ? 343 VAL   A N     1 
ATOM   3176 C CA    . VAL   D 2 331 ? 233.596 196.887 250.442 1.00 51.21  ? 343 VAL   A CA    1 
ATOM   3177 C C     . VAL   D 2 331 ? 234.630 195.789 250.669 1.00 47.03  ? 343 VAL   A C     1 
ATOM   3178 O O     . VAL   D 2 331 ? 234.328 194.597 250.539 1.00 48.17  ? 343 VAL   A O     1 
ATOM   3179 C CB    . VAL   D 2 331 ? 233.619 197.419 248.995 1.00 50.04  ? 343 VAL   A CB    1 
ATOM   3180 C CG1   . VAL   D 2 331 ? 234.866 198.214 248.730 1.00 52.93  ? 343 VAL   A CG1   1 
ATOM   3181 C CG2   . VAL   D 2 331 ? 233.500 196.279 248.000 1.00 50.40  ? 343 VAL   A CG2   1 
ATOM   3182 N N     . SER   D 2 332 ? 235.862 196.168 251.017 1.00 46.57  ? 344 SER   A N     1 
ATOM   3183 C CA    . SER   D 2 332 ? 236.885 195.171 251.320 1.00 45.53  ? 344 SER   A CA    1 
ATOM   3184 C C     . SER   D 2 332 ? 236.493 194.328 252.526 1.00 46.68  ? 344 SER   A C     1 
ATOM   3185 O O     . SER   D 2 332 ? 236.677 193.106 252.523 1.00 47.34  ? 344 SER   A O     1 
ATOM   3186 C CB    . SER   D 2 332 ? 238.230 195.854 251.558 1.00 45.98  ? 344 SER   A CB    1 
ATOM   3187 O OG    . SER   D 2 332 ? 238.857 196.185 250.335 1.00 50.50  ? 344 SER   A OG    1 
ATOM   3188 N N     . SER   D 2 333 ? 235.954 194.963 253.569 1.00 48.55  ? 345 SER   A N     1 
ATOM   3189 C CA    . SER   D 2 333 ? 235.490 194.219 254.735 1.00 47.66  ? 345 SER   A CA    1 
ATOM   3190 C C     . SER   D 2 333 ? 234.284 193.355 254.396 1.00 48.25  ? 345 SER   A C     1 
ATOM   3191 O O     . SER   D 2 333 ? 234.145 192.243 254.918 1.00 53.13  ? 345 SER   A O     1 
ATOM   3192 C CB    . SER   D 2 333 ? 235.152 195.180 255.873 1.00 47.25  ? 345 SER   A CB    1 
ATOM   3193 O OG    . SER   D 2 333 ? 236.096 196.231 255.945 1.00 51.30  ? 345 SER   A OG    1 
ATOM   3194 N N     . PHE   D 2 334 ? 233.394 193.855 253.538 1.00 47.07  ? 346 PHE   A N     1 
ATOM   3195 C CA    . PHE   D 2 334 ? 232.240 193.065 253.125 1.00 48.19  ? 346 PHE   A CA    1 
ATOM   3196 C C     . PHE   D 2 334 ? 232.673 191.808 252.385 1.00 46.68  ? 346 PHE   A C     1 
ATOM   3197 O O     . PHE   D 2 334 ? 232.116 190.727 252.600 1.00 47.86  ? 346 PHE   A O     1 
ATOM   3198 C CB    . PHE   D 2 334 ? 231.320 193.917 252.251 1.00 48.59  ? 346 PHE   A CB    1 
ATOM   3199 C CG    . PHE   D 2 334 ? 229.947 193.349 252.088 1.00 48.60  ? 346 PHE   A CG    1 
ATOM   3200 C CD1   . PHE   D 2 334 ? 229.102 193.234 253.175 1.00 48.31  ? 346 PHE   A CD1   1 
ATOM   3201 C CD2   . PHE   D 2 334 ? 229.497 192.934 250.850 1.00 48.26  ? 346 PHE   A CD2   1 
ATOM   3202 C CE1   . PHE   D 2 334 ? 227.838 192.713 253.031 1.00 46.82  ? 346 PHE   A CE1   1 
ATOM   3203 C CE2   . PHE   D 2 334 ? 228.233 192.412 250.703 1.00 50.91  ? 346 PHE   A CE2   1 
ATOM   3204 C CZ    . PHE   D 2 334 ? 227.404 192.301 251.795 1.00 50.99  ? 346 PHE   A CZ    1 
ATOM   3205 N N     . ILE   D 2 335 ? 233.666 191.935 251.506 1.00 48.90  ? 347 ILE   A N     1 
ATOM   3206 C CA    . ILE   D 2 335 ? 234.150 190.785 250.751 1.00 48.91  ? 347 ILE   A CA    1 
ATOM   3207 C C     . ILE   D 2 335 ? 234.918 189.829 251.656 1.00 49.01  ? 347 ILE   A C     1 
ATOM   3208 O O     . ILE   D 2 335 ? 234.776 188.605 251.553 1.00 50.28  ? 347 ILE   A O     1 
ATOM   3209 C CB    . ILE   D 2 335 ? 235.002 191.260 249.561 1.00 45.72  ? 347 ILE   A CB    1 
ATOM   3210 C CG1   . ILE   D 2 335 ? 234.114 191.963 248.537 1.00 44.18  ? 347 ILE   A CG1   1 
ATOM   3211 C CG2   . ILE   D 2 335 ? 235.738 190.100 248.924 1.00 46.82  ? 347 ILE   A CG2   1 
ATOM   3212 C CD1   . ILE   D 2 335 ? 234.873 192.600 247.418 1.00 49.90  ? 347 ILE   A CD1   1 
ATOM   3213 N N     . ARG   D 2 336 ? 235.740 190.366 252.557 1.00 47.52  ? 348 ARG   A N     1 
ATOM   3214 C CA    . ARG   D 2 336 ? 236.545 189.526 253.434 1.00 48.11  ? 348 ARG   A CA    1 
ATOM   3215 C C     . ARG   D 2 336 ? 235.726 188.917 254.566 1.00 49.89  ? 348 ARG   A C     1 
ATOM   3216 O O     . ARG   D 2 336 ? 235.998 187.786 254.982 1.00 52.80  ? 348 ARG   A O     1 
ATOM   3217 C CB    . ARG   D 2 336 ? 237.707 190.343 254.000 1.00 45.59  ? 348 ARG   A CB    1 
ATOM   3218 C CG    . ARG   D 2 336 ? 238.619 189.587 254.941 1.00 48.90  ? 348 ARG   A CG    1 
ATOM   3219 C CD    . ARG   D 2 336 ? 239.980 190.247 255.023 1.00 49.61  ? 348 ARG   A CD    1 
ATOM   3220 N NE    . ARG   D 2 336 ? 240.756 189.768 256.159 1.00 45.10  ? 348 ARG   A NE    1 
ATOM   3221 C CZ    . ARG   D 2 336 ? 241.355 188.587 256.214 1.00 47.16  ? 348 ARG   A CZ    1 
ATOM   3222 N NH1   . ARG   D 2 336 ? 241.296 187.734 255.205 1.00 46.80  ? 348 ARG   A NH1   1 
ATOM   3223 N NH2   . ARG   D 2 336 ? 242.030 188.253 257.308 1.00 49.80  ? 348 ARG   A NH2   1 
ATOM   3224 N N     . GLY   D 2 337 ? 234.727 189.637 255.068 1.00 46.53  ? 349 GLY   A N     1 
ATOM   3225 C CA    . GLY   D 2 337 ? 233.954 189.200 256.205 1.00 42.53  ? 349 GLY   A CA    1 
ATOM   3226 C C     . GLY   D 2 337 ? 234.512 189.630 257.544 1.00 48.68  ? 349 GLY   A C     1 
ATOM   3227 O O     . GLY   D 2 337 ? 233.778 189.629 258.537 1.00 59.27  ? 349 GLY   A O     1 
ATOM   3228 N N     . THR   D 2 338 ? 235.785 190.002 257.593 1.00 49.44  ? 350 THR   A N     1 
ATOM   3229 C CA    . THR   D 2 338 ? 236.425 190.546 258.777 1.00 49.07  ? 350 THR   A CA    1 
ATOM   3230 C C     . THR   D 2 338 ? 236.793 191.998 258.505 1.00 53.79  ? 350 THR   A C     1 
ATOM   3231 O O     . THR   D 2 338 ? 237.035 192.384 257.359 1.00 59.61  ? 350 THR   A O     1 
ATOM   3232 C CB    . THR   D 2 338 ? 237.678 189.744 259.145 1.00 52.23  ? 350 THR   A CB    1 
ATOM   3233 O OG1   . THR   D 2 338 ? 237.407 188.344 259.006 1.00 58.06  ? 350 THR   A OG1   1 
ATOM   3234 C CG2   . THR   D 2 338 ? 238.092 190.021 260.578 1.00 58.13  ? 350 THR   A CG2   1 
ATOM   3235 N N     . LYS   D 2 339 ? 236.815 192.805 259.561 1.00 52.01  ? 351 LYS   A N     1 
ATOM   3236 C CA    . LYS   D 2 339 ? 237.087 194.226 259.400 1.00 52.55  ? 351 LYS   A CA    1 
ATOM   3237 C C     . LYS   D 2 339 ? 238.486 194.446 258.847 1.00 51.14  ? 351 LYS   A C     1 
ATOM   3238 O O     . LYS   D 2 339 ? 239.474 193.989 259.428 1.00 53.34  ? 351 LYS   A O     1 
ATOM   3239 C CB    . LYS   D 2 339 ? 236.926 194.949 260.734 1.00 53.31  ? 351 LYS   A CB    1 
ATOM   3240 C CG    . LYS   D 2 339 ? 235.511 194.936 261.279 1.00 58.99  ? 351 LYS   A CG    1 
ATOM   3241 C CD    . LYS   D 2 339 ? 235.275 196.009 262.342 1.00 59.28  ? 351 LYS   A CD    1 
ATOM   3242 C CE    . LYS   D 2 339 ? 235.988 197.332 262.070 1.00 60.13  ? 351 LYS   A CE    1 
ATOM   3243 N NZ    . LYS   D 2 339 ? 235.919 197.811 260.658 1.00 69.33  ? 351 LYS   A NZ    1 
ATOM   3244 N N     . VAL   D 2 340 ? 238.567 195.144 257.720 1.00 47.74  ? 352 VAL   A N     1 
ATOM   3245 C CA    . VAL   D 2 340 ? 239.849 195.558 257.165 1.00 46.71  ? 352 VAL   A CA    1 
ATOM   3246 C C     . VAL   D 2 340 ? 240.263 196.837 257.884 1.00 47.36  ? 352 VAL   A C     1 
ATOM   3247 O O     . VAL   D 2 340 ? 239.717 197.913 257.632 1.00 49.40  ? 352 VAL   A O     1 
ATOM   3248 C CB    . VAL   D 2 340 ? 239.773 195.762 255.649 1.00 47.73  ? 352 VAL   A CB    1 
ATOM   3249 C CG1   . VAL   D 2 340 ? 241.043 196.408 255.140 1.00 51.92  ? 352 VAL   A CG1   1 
ATOM   3250 C CG2   . VAL   D 2 340 ? 239.550 194.433 254.957 1.00 45.69  ? 352 VAL   A CG2   1 
ATOM   3251 N N     . VAL   D 2 341 ? 241.213 196.711 258.801 1.00 46.76  ? 353 VAL   A N     1 
ATOM   3252 C CA    . VAL   D 2 341 ? 241.676 197.813 259.635 1.00 44.25  ? 353 VAL   A CA    1 
ATOM   3253 C C     . VAL   D 2 341 ? 242.582 198.719 258.808 1.00 47.60  ? 353 VAL   A C     1 
ATOM   3254 O O     . VAL   D 2 341 ? 243.361 198.221 257.983 1.00 49.44  ? 353 VAL   A O     1 
ATOM   3255 C CB    . VAL   D 2 341 ? 242.383 197.268 260.887 1.00 44.66  ? 353 VAL   A CB    1 
ATOM   3256 C CG1   . VAL   D 2 341 ? 243.242 198.321 261.528 1.00 50.89  ? 353 VAL   A CG1   1 
ATOM   3257 C CG2   . VAL   D 2 341 ? 241.357 196.756 261.880 1.00 42.78  ? 353 VAL   A CG2   1 
ATOM   3258 N N     . PRO   D 2 342 ? 242.501 200.039 258.969 1.00 50.93  ? 354 PRO   A N     1 
ATOM   3259 C CA    . PRO   D 2 342 ? 243.407 200.934 258.239 1.00 50.40  ? 354 PRO   A CA    1 
ATOM   3260 C C     . PRO   D 2 342 ? 244.862 200.680 258.605 1.00 50.33  ? 354 PRO   A C     1 
ATOM   3261 O O     . PRO   D 2 342 ? 245.188 199.994 259.575 1.00 52.10  ? 354 PRO   A O     1 
ATOM   3262 C CB    . PRO   D 2 342 ? 242.954 202.336 258.668 1.00 47.97  ? 354 PRO   A CB    1 
ATOM   3263 C CG    . PRO   D 2 342 ? 242.071 202.125 259.860 1.00 47.24  ? 354 PRO   A CG    1 
ATOM   3264 C CD    . PRO   D 2 342 ? 241.456 200.783 259.689 1.00 50.47  ? 354 PRO   A CD    1 
ATOM   3265 N N     . ARG   D 2 343 ? 245.752 201.254 257.794 1.00 46.60  ? 355 ARG   A N     1 
ATOM   3266 C CA    . ARG   D 2 343 ? 247.179 200.986 257.944 1.00 47.99  ? 355 ARG   A CA    1 
ATOM   3267 C C     . ARG   D 2 343 ? 247.701 201.472 259.289 1.00 49.41  ? 355 ARG   A C     1 
ATOM   3268 O O     . ARG   D 2 343 ? 248.587 200.846 259.882 1.00 49.12  ? 355 ARG   A O     1 
ATOM   3269 C CB    . ARG   D 2 343 ? 247.951 201.641 256.799 1.00 46.64  ? 355 ARG   A CB    1 
ATOM   3270 C CG    . ARG   D 2 343 ? 249.444 201.396 256.831 1.00 44.27  ? 355 ARG   A CG    1 
ATOM   3271 C CD    . ARG   D 2 343 ? 249.785 199.988 256.405 1.00 42.82  ? 355 ARG   A CD    1 
ATOM   3272 N NE    . ARG   D 2 343 ? 251.223 199.760 256.389 1.00 47.05  ? 355 ARG   A NE    1 
ATOM   3273 C CZ    . ARG   D 2 343 ? 251.914 199.294 257.420 1.00 42.68  ? 355 ARG   A CZ    1 
ATOM   3274 N NH1   . ARG   D 2 343 ? 251.329 199.003 258.569 1.00 42.04  ? 355 ARG   A NH1   1 
ATOM   3275 N NH2   . ARG   D 2 343 ? 253.225 199.117 257.294 1.00 39.58  ? 355 ARG   A NH2   1 
ATOM   3276 N N     . GLY   D 2 344 ? 247.164 202.584 259.787 1.00 52.13  ? 356 GLY   A N     1 
ATOM   3277 C CA    . GLY   D 2 344 ? 247.654 203.138 261.036 1.00 47.40  ? 356 GLY   A CA    1 
ATOM   3278 C C     . GLY   D 2 344 ? 247.441 202.227 262.228 1.00 47.87  ? 356 GLY   A C     1 
ATOM   3279 O O     . GLY   D 2 344 ? 248.255 202.211 263.153 1.00 52.07  ? 356 GLY   A O     1 
ATOM   3280 N N     . LYS   D 2 345 ? 246.353 201.462 262.229 1.00 47.99  ? 357 LYS   A N     1 
ATOM   3281 C CA    . LYS   D 2 345 ? 246.000 200.628 263.368 1.00 50.32  ? 357 LYS   A CA    1 
ATOM   3282 C C     . LYS   D 2 345 ? 246.409 199.172 263.189 1.00 47.93  ? 357 LYS   A C     1 
ATOM   3283 O O     . LYS   D 2 345 ? 246.022 198.328 264.001 1.00 47.28  ? 357 LYS   A O     1 
ATOM   3284 C CB    . LYS   D 2 345 ? 244.500 200.724 263.645 1.00 47.79  ? 357 LYS   A CB    1 
ATOM   3285 C CG    . LYS   D 2 345 ? 243.918 202.101 263.418 1.00 49.33  ? 357 LYS   A CG    1 
ATOM   3286 C CD    . LYS   D 2 345 ? 242.644 202.289 264.210 1.00 45.66  ? 357 LYS   A CD    1 
ATOM   3287 C CE    . LYS   D 2 345 ? 242.947 202.419 265.686 1.00 46.96  ? 357 LYS   A CE    1 
ATOM   3288 N NZ    . LYS   D 2 345 ? 244.022 203.415 265.927 1.00 47.79  ? 357 LYS   A NZ    1 
ATOM   3289 N N     . LEU   D 2 346 ? 247.177 198.859 262.149 1.00 50.45  ? 358 LEU   A N     1 
ATOM   3290 C CA    . LEU   D 2 346 ? 247.727 197.520 261.979 1.00 51.32  ? 358 LEU   A CA    1 
ATOM   3291 C C     . LEU   D 2 346 ? 249.000 197.392 262.805 1.00 53.28  ? 358 LEU   A C     1 
ATOM   3292 O O     . LEU   D 2 346 ? 249.991 198.078 262.537 1.00 55.59  ? 358 LEU   A O     1 
ATOM   3293 C CB    . LEU   D 2 346 ? 248.023 197.240 260.507 1.00 50.78  ? 358 LEU   A CB    1 
ATOM   3294 C CG    . LEU   D 2 346 ? 246.860 197.014 259.544 1.00 48.53  ? 358 LEU   A CG    1 
ATOM   3295 C CD1   . LEU   D 2 346 ? 247.374 196.481 258.221 1.00 46.28  ? 358 LEU   A CD1   1 
ATOM   3296 C CD2   . LEU   D 2 346 ? 245.844 196.066 260.139 1.00 49.84  ? 358 LEU   A CD2   1 
ATOM   3297 N N     . SER   D 2 347 ? 248.978 196.519 263.809 1.00 53.18  ? 359 SER   A N     1 
ATOM   3298 C CA    . SER   D 2 347 ? 250.157 196.284 264.640 1.00 56.19  ? 359 SER   A CA    1 
ATOM   3299 C C     . SER   D 2 347 ? 251.035 195.226 263.973 1.00 55.54  ? 359 SER   A C     1 
ATOM   3300 O O     . SER   D 2 347 ? 251.194 194.101 264.447 1.00 60.42  ? 359 SER   A O     1 
ATOM   3301 C CB    . SER   D 2 347 ? 249.747 195.877 266.048 1.00 54.60  ? 359 SER   A CB    1 
ATOM   3302 O OG    . SER   D 2 347 ? 249.105 194.616 266.043 1.00 63.25  ? 359 SER   A OG    1 
ATOM   3303 N N     . THR   D 2 348 ? 251.607 195.618 262.838 1.00 53.29  ? 360 THR   A N     1 
ATOM   3304 C CA    . THR   D 2 348 ? 252.439 194.720 262.052 1.00 54.07  ? 360 THR   A CA    1 
ATOM   3305 C C     . THR   D 2 348 ? 253.338 195.540 261.142 1.00 54.49  ? 360 THR   A C     1 
ATOM   3306 O O     . THR   D 2 348 ? 252.973 196.635 260.708 1.00 59.16  ? 360 THR   A O     1 
ATOM   3307 C CB    . THR   D 2 348 ? 251.598 193.751 261.214 1.00 55.38  ? 360 THR   A CB    1 
ATOM   3308 O OG1   . THR   D 2 348 ? 252.447 193.050 260.300 1.00 56.50  ? 360 THR   A OG1   1 
ATOM   3309 C CG2   . THR   D 2 348 ? 250.547 194.506 260.426 1.00 55.40  ? 360 THR   A CG2   1 
ATOM   3310 N N     . ARG   D 2 349 ? 254.514 194.999 260.867 1.00 53.68  ? 361 ARG   A N     1 
ATOM   3311 C CA    . ARG   D 2 349 ? 255.436 195.576 259.908 1.00 48.75  ? 361 ARG   A CA    1 
ATOM   3312 C C     . ARG   D 2 349 ? 255.351 194.787 258.603 1.00 50.76  ? 361 ARG   A C     1 
ATOM   3313 O O     . ARG   D 2 349 ? 254.481 193.930 258.426 1.00 53.46  ? 361 ARG   A O     1 
ATOM   3314 C CB    . ARG   D 2 349 ? 256.850 195.607 260.488 1.00 45.95  ? 361 ARG   A CB    1 
ATOM   3315 C CG    . ARG   D 2 349 ? 257.323 197.000 260.855 1.00 45.56  ? 361 ARG   A CG    1 
ATOM   3316 C CD    . ARG   D 2 349 ? 258.211 196.999 262.086 1.00 46.66  ? 361 ARG   A CD    1 
ATOM   3317 N NE    . ARG   D 2 349 ? 259.423 196.208 261.915 1.00 46.26  ? 361 ARG   A NE    1 
ATOM   3318 C CZ    . ARG   D 2 349 ? 260.439 196.540 261.130 1.00 45.16  ? 361 ARG   A CZ    1 
ATOM   3319 N NH1   . ARG   D 2 349 ? 260.419 197.643 260.402 1.00 49.57  ? 361 ARG   A NH1   1 
ATOM   3320 N NH2   . ARG   D 2 349 ? 261.502 195.746 261.076 1.00 44.99  ? 361 ARG   A NH2   1 
ATOM   3321 N N     . GLY   D 2 350 ? 256.255 195.073 257.678 1.00 53.40  ? 362 GLY   A N     1 
ATOM   3322 C CA    . GLY   D 2 350 ? 256.216 194.437 256.376 1.00 53.66  ? 362 GLY   A CA    1 
ATOM   3323 C C     . GLY   D 2 350 ? 256.417 192.936 256.456 1.00 52.12  ? 362 GLY   A C     1 
ATOM   3324 O O     . GLY   D 2 350 ? 256.847 192.374 257.462 1.00 55.69  ? 362 GLY   A O     1 
ATOM   3325 N N     . VAL   D 2 351 ? 256.075 192.273 255.351 1.00 49.00  ? 363 VAL   A N     1 
ATOM   3326 C CA    . VAL   D 2 351 ? 256.221 190.823 255.280 1.00 48.63  ? 363 VAL   A CA    1 
ATOM   3327 C C     . VAL   D 2 351 ? 257.689 190.423 255.362 1.00 51.81  ? 363 VAL   A C     1 
ATOM   3328 O O     . VAL   D 2 351 ? 258.052 189.493 256.090 1.00 59.48  ? 363 VAL   A O     1 
ATOM   3329 C CB    . VAL   D 2 351 ? 255.555 190.286 254.000 1.00 49.65  ? 363 VAL   A CB    1 
ATOM   3330 C CG1   . VAL   D 2 351 ? 256.057 188.893 253.681 1.00 48.67  ? 363 VAL   A CG1   1 
ATOM   3331 C CG2   . VAL   D 2 351 ? 254.048 190.287 254.150 1.00 51.16  ? 363 VAL   A CG2   1 
ATOM   3332 N N     . GLN   D 2 352 ? 258.554 191.121 254.632 1.00 47.49  ? 364 GLN   A N     1 
ATOM   3333 C CA    . GLN   D 2 352 ? 259.951 190.723 254.540 1.00 49.66  ? 364 GLN   A CA    1 
ATOM   3334 C C     . GLN   D 2 352 ? 260.684 190.963 255.854 1.00 50.93  ? 364 GLN   A C     1 
ATOM   3335 O O     . GLN   D 2 352 ? 260.421 191.935 256.566 1.00 52.56  ? 364 GLN   A O     1 
ATOM   3336 C CB    . GLN   D 2 352 ? 260.642 191.481 253.410 1.00 50.48  ? 364 GLN   A CB    1 
ATOM   3337 C CG    . GLN   D 2 352 ? 260.207 191.038 252.031 1.00 53.97  ? 364 GLN   A CG    1 
ATOM   3338 C CD    . GLN   D 2 352 ? 261.335 191.074 251.029 1.00 58.64  ? 364 GLN   A CD    1 
ATOM   3339 O OE1   . GLN   D 2 352 ? 261.506 192.054 250.307 1.00 63.77  ? 364 GLN   A OE1   1 
ATOM   3340 N NE2   . GLN   D 2 352 ? 262.116 190.004 250.980 1.00 59.02  ? 364 GLN   A NE2   1 
ATOM   3341 N N     . ILE   D 2 353 ? 261.614 190.067 256.167 1.00 48.31  ? 365 ILE   A N     1 
ATOM   3342 C CA    . ILE   D 2 353 ? 262.405 190.135 257.389 1.00 50.05  ? 365 ILE   A CA    1 
ATOM   3343 C C     . ILE   D 2 353 ? 263.789 190.660 257.041 1.00 50.64  ? 365 ILE   A C     1 
ATOM   3344 O O     . ILE   D 2 353 ? 264.408 190.207 256.070 1.00 53.34  ? 365 ILE   A O     1 
ATOM   3345 C CB    . ILE   D 2 353 ? 262.492 188.761 258.074 1.00 51.44  ? 365 ILE   A CB    1 
ATOM   3346 C CG1   . ILE   D 2 353 ? 261.092 188.209 258.335 1.00 52.48  ? 365 ILE   A CG1   1 
ATOM   3347 C CG2   . ILE   D 2 353 ? 263.264 188.861 259.372 1.00 53.28  ? 365 ILE   A CG2   1 
ATOM   3348 C CD1   . ILE   D 2 353 ? 260.310 189.000 259.344 1.00 52.27  ? 365 ILE   A CD1   1 
ATOM   3349 N N     . ALA   D 2 354 ? 264.270 191.621 257.823 1.00 51.26  ? 366 ALA   A N     1 
ATOM   3350 C CA    . ALA   D 2 354 ? 265.572 192.216 257.579 1.00 50.82  ? 366 ALA   A CA    1 
ATOM   3351 C C     . ALA   D 2 354 ? 266.687 191.304 258.082 1.00 53.50  ? 366 ALA   A C     1 
ATOM   3352 O O     . ALA   D 2 354 ? 266.466 190.372 258.858 1.00 52.65  ? 366 ALA   A O     1 
ATOM   3353 C CB    . ALA   D 2 354 ? 265.675 193.585 258.248 1.00 53.41  ? 366 ALA   A CB    1 
ATOM   3354 N N     . SER   D 2 355 ? 267.906 191.593 257.626 1.00 55.77  ? 367 SER   A N     1 
ATOM   3355 C CA    . SER   D 2 355 ? 269.046 190.758 257.977 1.00 55.78  ? 367 SER   A CA    1 
ATOM   3356 C C     . SER   D 2 355 ? 269.524 190.988 259.403 1.00 56.84  ? 367 SER   A C     1 
ATOM   3357 O O     . SER   D 2 355 ? 270.231 190.136 259.948 1.00 64.48  ? 367 SER   A O     1 
ATOM   3358 C CB    . SER   D 2 355 ? 270.195 191.001 257.001 1.00 55.80  ? 367 SER   A CB    1 
ATOM   3359 O OG    . SER   D 2 355 ? 271.020 192.061 257.444 1.00 64.50  ? 367 SER   A OG    1 
ATOM   3360 N N     . ASN   D 2 356 ? 269.159 192.108 260.017 1.00 55.13  ? 368 ASN   A N     1 
ATOM   3361 C CA    . ASN   D 2 356 ? 269.610 192.426 261.364 1.00 54.53  ? 368 ASN   A CA    1 
ATOM   3362 C C     . ASN   D 2 356 ? 268.625 191.996 262.442 1.00 56.59  ? 368 ASN   A C     1 
ATOM   3363 O O     . ASN   D 2 356 ? 268.887 192.233 263.625 1.00 63.21  ? 368 ASN   A O     1 
ATOM   3364 C CB    . ASN   D 2 356 ? 269.884 193.928 261.489 1.00 54.94  ? 368 ASN   A CB    1 
ATOM   3365 C CG    . ASN   D 2 356 ? 268.664 194.773 261.189 1.00 55.86  ? 368 ASN   A CG    1 
ATOM   3366 O OD1   . ASN   D 2 356 ? 267.793 194.950 262.038 1.00 53.94  ? 368 ASN   A OD1   1 
ATOM   3367 N ND2   . ASN   D 2 356 ? 268.597 195.304 259.977 1.00 58.25  ? 368 ASN   A ND2   1 
ATOM   3368 N N     . GLU   D 2 357 ? 267.511 191.373 262.072 1.00 56.88  ? 369 GLU   A N     1 
ATOM   3369 C CA    . GLU   D 2 357 ? 266.507 191.000 263.056 1.00 55.67  ? 369 GLU   A CA    1 
ATOM   3370 C C     . GLU   D 2 357 ? 267.000 189.851 263.925 1.00 56.46  ? 369 GLU   A C     1 
ATOM   3371 O O     . GLU   D 2 357 ? 267.849 189.053 263.521 1.00 60.32  ? 369 GLU   A O     1 
ATOM   3372 C CB    . GLU   D 2 357 ? 265.201 190.609 262.367 1.00 53.86  ? 369 GLU   A CB    1 
ATOM   3373 C CG    . GLU   D 2 357 ? 264.719 191.607 261.336 1.00 55.61  ? 369 GLU   A CG    1 
ATOM   3374 C CD    . GLU   D 2 357 ? 263.445 192.306 261.752 1.00 56.74  ? 369 GLU   A CD    1 
ATOM   3375 O OE1   . GLU   D 2 357 ? 262.883 191.940 262.802 1.00 61.81  ? 369 GLU   A OE1   1 
ATOM   3376 O OE2   . GLU   D 2 357 ? 263.000 193.216 261.024 1.00 56.84  ? 369 GLU   A OE2   1 
ATOM   3377 N N     . ASN   D 2 358 ? 266.456 189.774 265.135 1.00 56.76  ? 370 ASN   A N     1 
ATOM   3378 C CA    . ASN   D 2 358 ? 266.815 188.721 266.080 1.00 56.33  ? 370 ASN   A CA    1 
ATOM   3379 C C     . ASN   D 2 358 ? 266.071 187.454 265.684 1.00 57.47  ? 370 ASN   A C     1 
ATOM   3380 O O     . ASN   D 2 358 ? 264.892 187.286 266.000 1.00 63.16  ? 370 ASN   A O     1 
ATOM   3381 C CB    . ASN   D 2 358 ? 266.476 189.138 267.506 1.00 54.59  ? 370 ASN   A CB    1 
ATOM   3382 C CG    . ASN   D 2 358 ? 266.952 188.135 268.531 1.00 56.42  ? 370 ASN   A CG    1 
ATOM   3383 O OD1   . ASN   D 2 358 ? 267.981 187.487 268.350 1.00 61.82  ? 370 ASN   A OD1   1 
ATOM   3384 N ND2   . ASN   D 2 358 ? 266.203 188.001 269.618 1.00 55.58  ? 370 ASN   A ND2   1 
ATOM   3385 N N     . MET   D 2 359 ? 266.757 186.556 264.987 1.00 56.34  ? 371 MET   A N     1 
ATOM   3386 C CA    . MET   D 2 359 ? 266.125 185.326 264.515 1.00 58.33  ? 371 MET   A CA    1 
ATOM   3387 C C     . MET   D 2 359 ? 266.152 184.239 265.584 1.00 61.93  ? 371 MET   A C     1 
ATOM   3388 O O     . MET   D 2 359 ? 266.545 183.099 265.347 1.00 68.63  ? 371 MET   A O     1 
ATOM   3389 C CB    . MET   D 2 359 ? 266.804 184.857 263.236 1.00 58.98  ? 371 MET   A CB    1 
ATOM   3390 C CG    . MET   D 2 359 ? 265.913 184.029 262.342 1.00 59.72  ? 371 MET   A CG    1 
ATOM   3391 S SD    . MET   D 2 359 ? 264.947 185.042 261.217 1.00 65.52  ? 371 MET   A SD    1 
ATOM   3392 C CE    . MET   D 2 359 ? 263.506 184.005 261.030 1.00 60.10  ? 371 MET   A CE    1 
ATOM   3393 N N     . GLU   D 2 360 ? 265.724 184.608 266.785 1.00 58.71  ? 372 GLU   A N     1 
ATOM   3394 C CA    . GLU   D 2 360 ? 265.528 183.665 267.874 1.00 57.38  ? 372 GLU   A CA    1 
ATOM   3395 C C     . GLU   D 2 360 ? 264.209 183.858 268.600 1.00 56.67  ? 372 GLU   A C     1 
ATOM   3396 O O     . GLU   D 2 360 ? 263.727 182.907 269.224 1.00 57.03  ? 372 GLU   A O     1 
ATOM   3397 C CB    . GLU   D 2 360 ? 266.677 183.764 268.888 1.00 57.98  ? 372 GLU   A CB    1 
ATOM   3398 C CG    . GLU   D 2 360 ? 266.939 182.480 269.648 1.00 68.23  ? 372 GLU   A CG    1 
ATOM   3399 C CD    . GLU   D 2 360 ? 268.415 182.190 269.807 1.00 77.76  ? 372 GLU   A CD    1 
ATOM   3400 O OE1   . GLU   D 2 360 ? 269.204 183.154 269.878 1.00 84.22  ? 372 GLU   A OE1   1 
ATOM   3401 O OE2   . GLU   D 2 360 ? 268.787 181.000 269.864 1.00 73.42  ? 372 GLU   A OE2   1 
ATOM   3402 N N     . THR   D 2 361 ? 263.613 185.045 268.540 1.00 55.39  ? 373 THR   A N     1 
ATOM   3403 C CA    . THR   D 2 361 ? 262.284 185.300 269.068 1.00 53.13  ? 373 THR   A CA    1 
ATOM   3404 C C     . THR   D 2 361 ? 261.212 185.282 267.989 1.00 55.70  ? 373 THR   A C     1 
ATOM   3405 O O     . THR   D 2 361 ? 260.029 185.430 268.307 1.00 62.04  ? 373 THR   A O     1 
ATOM   3406 C CB    . THR   D 2 361 ? 262.257 186.649 269.791 1.00 55.31  ? 373 THR   A CB    1 
ATOM   3407 O OG1   . THR   D 2 361 ? 262.768 187.665 268.920 1.00 56.10  ? 373 THR   A OG1   1 
ATOM   3408 C CG2   . THR   D 2 361 ? 263.108 186.597 271.045 1.00 55.14  ? 373 THR   A CG2   1 
ATOM   3409 N N     . MET   D 2 362 ? 261.595 185.109 266.728 1.00 57.52  ? 374 MET   A N     1 
ATOM   3410 C CA    . MET   D 2 362 ? 260.625 185.103 265.643 1.00 57.95  ? 374 MET   A CA    1 
ATOM   3411 C C     . MET   D 2 362 ? 259.770 183.846 265.704 1.00 57.76  ? 374 MET   A C     1 
ATOM   3412 O O     . MET   D 2 362 ? 260.264 182.755 266.000 1.00 59.85  ? 374 MET   A O     1 
ATOM   3413 C CB    . MET   D 2 362 ? 261.337 185.193 264.294 1.00 54.60  ? 374 MET   A CB    1 
ATOM   3414 C CG    . MET   D 2 362 ? 260.477 185.737 263.170 1.00 54.58  ? 374 MET   A CG    1 
ATOM   3415 S SD    . MET   D 2 362 ? 260.586 187.526 262.994 1.00 64.83  ? 374 MET   A SD    1 
ATOM   3416 C CE    . MET   D 2 362 ? 262.356 187.765 263.001 1.00 59.53  ? 374 MET   A CE    1 
ATOM   3417 N N     . GLU   D 2 363 ? 258.482 184.000 265.421 1.00 55.35  ? 375 GLU   A N     1 
ATOM   3418 C CA    . GLU   D 2 363 ? 257.551 182.883 265.438 1.00 54.08  ? 375 GLU   A CA    1 
ATOM   3419 C C     . GLU   D 2 363 ? 256.927 182.713 264.061 1.00 52.04  ? 375 GLU   A C     1 
ATOM   3420 O O     . GLU   D 2 363 ? 257.194 183.476 263.135 1.00 52.39  ? 375 GLU   A O     1 
ATOM   3421 C CB    . GLU   D 2 363 ? 256.466 183.084 266.503 1.00 55.05  ? 375 GLU   A CB    1 
ATOM   3422 C CG    . GLU   D 2 363 ? 256.986 183.053 267.928 1.00 57.84  ? 375 GLU   A CG    1 
ATOM   3423 C CD    . GLU   D 2 363 ? 257.326 181.653 268.406 1.00 74.01  ? 375 GLU   A CD    1 
ATOM   3424 O OE1   . GLU   D 2 363 ? 257.181 180.692 267.622 1.00 76.63  ? 375 GLU   A OE1   1 
ATOM   3425 O OE2   . GLU   D 2 363 ? 257.745 181.511 269.573 1.00 82.06  ? 375 GLU   A OE2   1 
ATOM   3426 N N     . SER   D 2 364 ? 256.082 181.698 263.931 1.00 55.47  ? 376 SER   A N     1 
ATOM   3427 C CA    . SER   D 2 364 ? 255.413 181.393 262.676 1.00 55.29  ? 376 SER   A CA    1 
ATOM   3428 C C     . SER   D 2 364 ? 253.909 181.337 262.891 1.00 56.49  ? 376 SER   A C     1 
ATOM   3429 O O     . SER   D 2 364 ? 253.435 180.798 263.896 1.00 57.97  ? 376 SER   A O     1 
ATOM   3430 C CB    . SER   D 2 364 ? 255.908 180.068 262.096 1.00 54.02  ? 376 SER   A CB    1 
ATOM   3431 O OG    . SER   D 2 364 ? 255.416 178.975 262.849 1.00 54.89  ? 376 SER   A OG    1 
ATOM   3432 N N     . SER   D 2 365 ? 253.160 181.894 261.944 1.00 53.46  ? 377 SER   A N     1 
ATOM   3433 C CA    . SER   D 2 365 ? 251.709 181.910 262.031 1.00 51.96  ? 377 SER   A CA    1 
ATOM   3434 C C     . SER   D 2 365 ? 251.099 181.574 260.680 1.00 52.95  ? 377 SER   A C     1 
ATOM   3435 O O     . SER   D 2 365 ? 251.671 181.867 259.627 1.00 55.41  ? 377 SER   A O     1 
ATOM   3436 C CB    . SER   D 2 365 ? 251.186 183.269 262.504 1.00 58.95  ? 377 SER   A CB    1 
ATOM   3437 O OG    . SER   D 2 365 ? 251.121 184.185 261.427 1.00 64.67  ? 377 SER   A OG    1 
ATOM   3438 N N     . THR   D 2 366 ? 249.921 180.962 260.725 1.00 52.12  ? 378 THR   A N     1 
ATOM   3439 C CA    . THR   D 2 366 ? 249.159 180.689 259.517 1.00 52.89  ? 378 THR   A CA    1 
ATOM   3440 C C     . THR   D 2 366 ? 248.436 181.950 259.066 1.00 53.25  ? 378 THR   A C     1 
ATOM   3441 O O     . THR   D 2 366 ? 247.907 182.706 259.885 1.00 54.76  ? 378 THR   A O     1 
ATOM   3442 C CB    . THR   D 2 366 ? 248.151 179.568 259.762 1.00 51.28  ? 378 THR   A CB    1 
ATOM   3443 O OG1   . THR   D 2 366 ? 248.743 178.568 260.598 1.00 53.90  ? 378 THR   A OG1   1 
ATOM   3444 C CG2   . THR   D 2 366 ? 247.736 178.934 258.451 1.00 54.28  ? 378 THR   A CG2   1 
ATOM   3445 N N     . LEU   D 2 367 ? 248.421 182.180 257.757 1.00 52.10  ? 379 LEU   A N     1 
ATOM   3446 C CA    . LEU   D 2 367 ? 247.801 183.367 257.192 1.00 53.44  ? 379 LEU   A CA    1 
ATOM   3447 C C     . LEU   D 2 367 ? 246.362 183.060 256.805 1.00 56.03  ? 379 LEU   A C     1 
ATOM   3448 O O     . LEU   D 2 367 ? 246.097 182.094 256.082 1.00 57.35  ? 379 LEU   A O     1 
ATOM   3449 C CB    . LEU   D 2 367 ? 248.588 183.858 255.977 1.00 53.03  ? 379 LEU   A CB    1 
ATOM   3450 C CG    . LEU   D 2 367 ? 249.978 184.429 256.256 1.00 51.27  ? 379 LEU   A CG    1 
ATOM   3451 C CD1   . LEU   D 2 367 ? 250.520 185.126 255.026 1.00 51.70  ? 379 LEU   A CD1   1 
ATOM   3452 C CD2   . LEU   D 2 367 ? 249.945 185.377 257.437 1.00 49.67  ? 379 LEU   A CD2   1 
ATOM   3453 N N     . GLU   D 2 368 ? 245.435 183.885 257.291 1.00 55.44  ? 380 GLU   A N     1 
ATOM   3454 C CA    . GLU   D 2 368 ? 244.012 183.718 257.003 1.00 55.16  ? 380 GLU   A CA    1 
ATOM   3455 C C     . GLU   D 2 368 ? 243.687 184.481 255.722 1.00 55.19  ? 380 GLU   A C     1 
ATOM   3456 O O     . GLU   D 2 368 ? 243.189 185.608 255.733 1.00 58.12  ? 380 GLU   A O     1 
ATOM   3457 C CB    . GLU   D 2 368 ? 243.171 184.191 258.182 1.00 56.39  ? 380 GLU   A CB    1 
ATOM   3458 C CG    . GLU   D 2 368 ? 241.674 184.022 258.000 1.00 59.09  ? 380 GLU   A CG    1 
ATOM   3459 C CD    . GLU   D 2 368 ? 241.240 182.578 258.070 1.00 74.28  ? 380 GLU   A CD    1 
ATOM   3460 O OE1   . GLU   D 2 368 ? 241.960 181.770 258.690 1.00 78.25  ? 380 GLU   A OE1   1 
ATOM   3461 O OE2   . GLU   D 2 368 ? 240.177 182.250 257.505 1.00 79.96  ? 380 GLU   A OE2   1 
ATOM   3462 N N     . LEU   D 2 369 ? 244.000 183.853 254.597 1.00 52.78  ? 381 LEU   A N     1 
ATOM   3463 C CA    . LEU   D 2 369 ? 243.707 184.412 253.277 1.00 52.67  ? 381 LEU   A CA    1 
ATOM   3464 C C     . LEU   D 2 369 ? 242.388 183.884 252.729 1.00 55.04  ? 381 LEU   A C     1 
ATOM   3465 O O     . LEU   D 2 369 ? 242.317 183.382 251.609 1.00 62.27  ? 381 LEU   A O     1 
ATOM   3466 C CB    . LEU   D 2 369 ? 244.852 184.113 252.321 1.00 50.77  ? 381 LEU   A CB    1 
ATOM   3467 C CG    . LEU   D 2 369 ? 246.219 184.601 252.791 1.00 51.93  ? 381 LEU   A CG    1 
ATOM   3468 C CD1   . LEU   D 2 369 ? 247.285 184.261 251.771 1.00 47.82  ? 381 LEU   A CD1   1 
ATOM   3469 C CD2   . LEU   D 2 369 ? 246.173 186.092 253.046 1.00 51.67  ? 381 LEU   A CD2   1 
ATOM   3470 N N     . ARG   D 2 370 ? 241.320 184.000 253.509 1.00 55.67  ? 382 ARG   A N     1 
ATOM   3471 C CA    . ARG   D 2 370 ? 240.011 183.490 253.134 1.00 51.72  ? 382 ARG   A CA    1 
ATOM   3472 C C     . ARG   D 2 370 ? 238.992 184.616 253.183 1.00 55.89  ? 382 ARG   A C     1 
ATOM   3473 O O     . ARG   D 2 370 ? 239.015 185.447 254.096 1.00 63.56  ? 382 ARG   A O     1 
ATOM   3474 C CB    . ARG   D 2 370 ? 239.577 182.353 254.060 1.00 55.56  ? 382 ARG   A CB    1 
ATOM   3475 C CG    . ARG   D 2 370 ? 240.022 180.981 253.604 1.00 58.60  ? 382 ARG   A CG    1 
ATOM   3476 C CD    . ARG   D 2 370 ? 239.067 179.910 254.087 1.00 60.06  ? 382 ARG   A CD    1 
ATOM   3477 N NE    . ARG   D 2 370 ? 239.047 179.823 255.541 1.00 62.25  ? 382 ARG   A NE    1 
ATOM   3478 C CZ    . ARG   D 2 370 ? 240.000 179.263 256.270 1.00 67.65  ? 382 ARG   A CZ    1 
ATOM   3479 N NH1   . ARG   D 2 370 ? 241.062 178.709 255.711 1.00 71.38  ? 382 ARG   A NH1   1 
ATOM   3480 N NH2   . ARG   D 2 370 ? 239.884 179.256 257.594 1.00 71.66  ? 382 ARG   A NH2   1 
ATOM   3481 N N     . SER   D 2 371 ? 238.098 184.640 252.202 1.00 51.01  ? 383 SER   A N     1 
ATOM   3482 C CA    . SER   D 2 371 ? 237.070 185.662 252.111 1.00 49.54  ? 383 SER   A CA    1 
ATOM   3483 C C     . SER   D 2 371 ? 235.697 185.013 252.025 1.00 51.88  ? 383 SER   A C     1 
ATOM   3484 O O     . SER   D 2 371 ? 235.540 183.922 251.470 1.00 60.88  ? 383 SER   A O     1 
ATOM   3485 C CB    . SER   D 2 371 ? 237.296 186.565 250.899 1.00 49.55  ? 383 SER   A CB    1 
ATOM   3486 O OG    . SER   D 2 371 ? 237.329 185.803 249.711 1.00 51.63  ? 383 SER   A OG    1 
ATOM   3487 N N     . ARG   D 2 372 ? 234.701 185.693 252.595 1.00 48.25  ? 384 ARG   A N     1 
ATOM   3488 C CA    . ARG   D 2 372 ? 233.339 185.176 252.551 1.00 50.17  ? 384 ARG   A CA    1 
ATOM   3489 C C     . ARG   D 2 372 ? 232.741 185.300 251.156 1.00 49.44  ? 384 ARG   A C     1 
ATOM   3490 O O     . ARG   D 2 372 ? 232.120 184.357 250.653 1.00 50.63  ? 384 ARG   A O     1 
ATOM   3491 C CB    . ARG   D 2 372 ? 232.471 185.907 253.571 1.00 50.27  ? 384 ARG   A CB    1 
ATOM   3492 C CG    . ARG   D 2 372 ? 231.305 185.089 254.070 1.00 47.93  ? 384 ARG   A CG    1 
ATOM   3493 C CD    . ARG   D 2 372 ? 230.140 185.980 254.468 1.00 52.86  ? 384 ARG   A CD    1 
ATOM   3494 N NE    . ARG   D 2 372 ? 228.920 185.249 254.797 1.00 57.78  ? 384 ARG   A NE    1 
ATOM   3495 C CZ    . ARG   D 2 372 ? 228.358 184.301 254.057 1.00 64.85  ? 384 ARG   A CZ    1 
ATOM   3496 N NH1   . ARG   D 2 372 ? 228.818 183.985 252.857 1.00 63.60  ? 384 ARG   A NH1   1 
ATOM   3497 N NH2   . ARG   D 2 372 ? 227.284 183.670 254.522 1.00 75.70  ? 384 ARG   A NH2   1 
ATOM   3498 N N     . TYR   D 2 373 ? 232.916 186.449 250.519 1.00 48.43  ? 385 TYR   A N     1 
ATOM   3499 C CA    . TYR   D 2 373 ? 232.395 186.708 249.186 1.00 52.18  ? 385 TYR   A CA    1 
ATOM   3500 C C     . TYR   D 2 373 ? 233.548 186.881 248.208 1.00 52.89  ? 385 TYR   A C     1 
ATOM   3501 O O     . TYR   D 2 373 ? 234.710 187.022 248.595 1.00 56.01  ? 385 TYR   A O     1 
ATOM   3502 C CB    . TYR   D 2 373 ? 231.501 187.954 249.183 1.00 54.80  ? 385 TYR   A CB    1 
ATOM   3503 C CG    . TYR   D 2 373 ? 230.265 187.845 250.048 1.00 53.09  ? 385 TYR   A CG    1 
ATOM   3504 C CD1   . TYR   D 2 373 ? 229.238 186.975 249.719 1.00 52.74  ? 385 TYR   A CD1   1 
ATOM   3505 C CD2   . TYR   D 2 373 ? 230.128 188.613 251.195 1.00 51.26  ? 385 TYR   A CD2   1 
ATOM   3506 C CE1   . TYR   D 2 373 ? 228.109 186.874 250.507 1.00 54.11  ? 385 TYR   A CE1   1 
ATOM   3507 C CE2   . TYR   D 2 373 ? 229.003 188.516 251.990 1.00 50.11  ? 385 TYR   A CE2   1 
ATOM   3508 C CZ    . TYR   D 2 373 ? 227.999 187.646 251.639 1.00 54.24  ? 385 TYR   A CZ    1 
ATOM   3509 O OH    . TYR   D 2 373 ? 226.877 187.546 252.424 1.00 60.23  ? 385 TYR   A OH    1 
ATOM   3510 N N     . TRP   D 2 374 ? 233.216 186.856 246.922 1.00 51.48  ? 386 TRP   A N     1 
ATOM   3511 C CA    . TRP   D 2 374 ? 234.179 187.144 245.873 1.00 50.23  ? 386 TRP   A CA    1 
ATOM   3512 C C     . TRP   D 2 374 ? 233.550 188.095 244.869 1.00 53.79  ? 386 TRP   A C     1 
ATOM   3513 O O     . TRP   D 2 374 ? 232.333 188.093 244.668 1.00 60.14  ? 386 TRP   A O     1 
ATOM   3514 C CB    . TRP   D 2 374 ? 234.674 185.864 245.177 1.00 50.21  ? 386 TRP   A CB    1 
ATOM   3515 C CG    . TRP   D 2 374 ? 233.740 185.273 244.168 1.00 50.94  ? 386 TRP   A CG    1 
ATOM   3516 C CD1   . TRP   D 2 374 ? 232.815 184.296 244.384 1.00 53.58  ? 386 TRP   A CD1   1 
ATOM   3517 C CD2   . TRP   D 2 374 ? 233.666 185.592 242.774 1.00 49.51  ? 386 TRP   A CD2   1 
ATOM   3518 N NE1   . TRP   D 2 374 ? 232.156 184.000 243.217 1.00 50.45  ? 386 TRP   A NE1   1 
ATOM   3519 C CE2   . TRP   D 2 374 ? 232.661 184.782 242.214 1.00 49.83  ? 386 TRP   A CE2   1 
ATOM   3520 C CE3   . TRP   D 2 374 ? 234.344 186.491 241.949 1.00 49.63  ? 386 TRP   A CE3   1 
ATOM   3521 C CZ2   . TRP   D 2 374 ? 232.319 184.845 240.869 1.00 53.36  ? 386 TRP   A CZ2   1 
ATOM   3522 C CZ3   . TRP   D 2 374 ? 234.003 186.550 240.615 1.00 48.81  ? 386 TRP   A CZ3   1 
ATOM   3523 C CH2   . TRP   D 2 374 ? 233.001 185.734 240.087 1.00 53.10  ? 386 TRP   A CH2   1 
ATOM   3524 N N     . ALA   D 2 375 ? 234.389 188.917 244.248 1.00 50.46  ? 387 ALA   A N     1 
ATOM   3525 C CA    . ALA   D 2 375 ? 233.916 189.938 243.329 1.00 52.68  ? 387 ALA   A CA    1 
ATOM   3526 C C     . ALA   D 2 375 ? 234.833 190.000 242.118 1.00 53.08  ? 387 ALA   A C     1 
ATOM   3527 O O     . ALA   D 2 375 ? 235.986 189.565 242.157 1.00 53.46  ? 387 ALA   A O     1 
ATOM   3528 C CB    . ALA   D 2 375 ? 233.833 191.310 244.004 1.00 54.50  ? 387 ALA   A CB    1 
ATOM   3529 N N     . ILE   D 2 376 ? 234.298 190.548 241.035 1.00 55.88  ? 388 ILE   A N     1 
ATOM   3530 C CA    . ILE   D 2 376 ? 235.055 190.703 239.801 1.00 55.06  ? 388 ILE   A CA    1 
ATOM   3531 C C     . ILE   D 2 376 ? 235.951 191.926 239.922 1.00 55.36  ? 388 ILE   A C     1 
ATOM   3532 O O     . ILE   D 2 376 ? 235.500 193.005 240.323 1.00 56.44  ? 388 ILE   A O     1 
ATOM   3533 C CB    . ILE   D 2 376 ? 234.110 190.823 238.596 1.00 52.80  ? 388 ILE   A CB    1 
ATOM   3534 C CG1   . ILE   D 2 376 ? 233.203 189.599 238.510 1.00 52.72  ? 388 ILE   A CG1   1 
ATOM   3535 C CG2   . ILE   D 2 376 ? 234.900 190.984 237.313 1.00 52.93  ? 388 ILE   A CG2   1 
ATOM   3536 C CD1   . ILE   D 2 376 ? 232.043 189.774 237.566 1.00 56.69  ? 388 ILE   A CD1   1 
ATOM   3537 N N     . ARG   D 2 377 ? 237.225 191.759 239.587 1.00 52.70  ? 389 ARG   A N     1 
ATOM   3538 C CA    . ARG   D 2 377 ? 238.159 192.872 239.601 1.00 53.54  ? 389 ARG   A CA    1 
ATOM   3539 C C     . ARG   D 2 377 ? 238.022 193.670 238.313 1.00 54.57  ? 389 ARG   A C     1 
ATOM   3540 O O     . ARG   D 2 377 ? 237.972 193.099 237.219 1.00 54.82  ? 389 ARG   A O     1 
ATOM   3541 C CB    . ARG   D 2 377 ? 239.588 192.367 239.781 1.00 52.49  ? 389 ARG   A CB    1 
ATOM   3542 C CG    . ARG   D 2 377 ? 240.017 192.316 241.230 1.00 52.02  ? 389 ARG   A CG    1 
ATOM   3543 C CD    . ARG   D 2 377 ? 240.945 191.153 241.510 1.00 51.72  ? 389 ARG   A CD    1 
ATOM   3544 N NE    . ARG   D 2 377 ? 240.456 189.888 240.973 1.00 53.44  ? 389 ARG   A NE    1 
ATOM   3545 C CZ    . ARG   D 2 377 ? 239.423 189.213 241.459 1.00 50.65  ? 389 ARG   A CZ    1 
ATOM   3546 N NH1   . ARG   D 2 377 ? 238.719 189.669 242.479 1.00 52.64  ? 389 ARG   A NH1   1 
ATOM   3547 N NH2   . ARG   D 2 377 ? 239.088 188.053 240.905 1.00 50.92  ? 389 ARG   A NH2   1 
ATOM   3548 N N     . THR   D 2 378 ? 237.967 194.989 238.444 1.00 56.77  ? 390 THR   A N     1 
ATOM   3549 C CA    . THR   D 2 378 ? 237.592 195.866 237.349 1.00 54.10  ? 390 THR   A CA    1 
ATOM   3550 C C     . THR   D 2 378 ? 238.773 196.710 236.891 1.00 55.62  ? 390 THR   A C     1 
ATOM   3551 O O     . THR   D 2 378 ? 239.698 196.992 237.657 1.00 61.41  ? 390 THR   A O     1 
ATOM   3552 C CB    . THR   D 2 378 ? 236.435 196.784 237.758 1.00 53.41  ? 390 THR   A CB    1 
ATOM   3553 O OG1   . THR   D 2 378 ? 236.058 197.606 236.647 1.00 65.16  ? 390 THR   A OG1   1 
ATOM   3554 C CG2   . THR   D 2 378 ? 236.839 197.672 238.920 1.00 45.32  ? 390 THR   A CG2   1 
ATOM   3555 N N     . ARG   D 2 379 ? 238.736 197.092 235.620 1.00 51.09  ? 391 ARG   A N     1 
ATOM   3556 C CA    . ARG   D 2 379 ? 239.638 198.109 235.104 1.00 52.42  ? 391 ARG   A CA    1 
ATOM   3557 C C     . ARG   D 2 379 ? 239.036 199.502 235.216 1.00 54.70  ? 391 ARG   A C     1 
ATOM   3558 O O     . ARG   D 2 379 ? 239.769 200.476 235.416 1.00 58.68  ? 391 ARG   A O     1 
ATOM   3559 C CB    . ARG   D 2 379 ? 239.998 197.796 233.648 1.00 52.48  ? 391 ARG   A CB    1 
ATOM   3560 C CG    . ARG   D 2 379 ? 240.457 198.981 232.823 1.00 58.12  ? 391 ARG   A CG    1 
ATOM   3561 C CD    . ARG   D 2 379 ? 240.622 198.598 231.364 1.00 66.00  ? 391 ARG   A CD    1 
ATOM   3562 N NE    . ARG   D 2 379 ? 241.714 197.654 231.163 1.00 69.14  ? 391 ARG   A NE    1 
ATOM   3563 C CZ    . ARG   D 2 379 ? 242.983 198.000 230.999 1.00 68.98  ? 391 ARG   A CZ    1 
ATOM   3564 N NH1   . ARG   D 2 379 ? 243.360 199.268 231.001 1.00 64.56  ? 391 ARG   A NH1   1 
ATOM   3565 N NH2   . ARG   D 2 379 ? 243.897 197.050 230.827 1.00 64.66  ? 391 ARG   A NH2   1 
ATOM   3566 N N     . SER   D 2 380 ? 237.711 199.602 235.139 1.00 54.72  ? 392 SER   A N     1 
ATOM   3567 C CA    . SER   D 2 380 ? 237.034 200.888 235.198 1.00 53.98  ? 392 SER   A CA    1 
ATOM   3568 C C     . SER   D 2 380 ? 237.251 201.565 236.545 1.00 54.73  ? 392 SER   A C     1 
ATOM   3569 O O     . SER   D 2 380 ? 237.355 200.914 237.587 1.00 58.78  ? 392 SER   A O     1 
ATOM   3570 C CB    . SER   D 2 380 ? 235.537 200.707 234.950 1.00 51.70  ? 392 SER   A CB    1 
ATOM   3571 O OG    . SER   D 2 380 ? 234.948 201.905 234.482 1.00 63.50  ? 392 SER   A OG    1 
ATOM   3572 N N     . GLY   D 2 381 ? 237.326 202.891 236.512 1.00 54.49  ? 393 GLY   A N     1 
ATOM   3573 C CA    . GLY   D 2 381 ? 237.397 203.707 237.702 1.00 54.05  ? 393 GLY   A CA    1 
ATOM   3574 C C     . GLY   D 2 381 ? 236.076 204.296 238.137 1.00 55.60  ? 393 GLY   A C     1 
ATOM   3575 O O     . GLY   D 2 381 ? 236.064 205.195 238.985 1.00 58.04  ? 393 GLY   A O     1 
ATOM   3576 N N     . GLY   D 2 382 ? 234.967 203.824 237.589 1.00 55.11  ? 394 GLY   A N     1 
ATOM   3577 C CA    . GLY   D 2 382 ? 233.656 204.338 237.902 1.00 55.27  ? 394 GLY   A CA    1 
ATOM   3578 C C     . GLY   D 2 382 ? 233.016 205.020 236.712 1.00 58.26  ? 394 GLY   A C     1 
ATOM   3579 O O     . GLY   D 2 382 ? 233.466 204.909 235.569 1.00 61.88  ? 394 GLY   A O     1 
ATOM   3580 N N     . ASN   D 2 383 ? 231.940 205.745 236.993 1.00 61.16  ? 395 ASN   A N     1 
ATOM   3581 C CA    . ASN   D 2 383 ? 231.260 206.537 235.982 1.00 64.84  ? 395 ASN   A CA    1 
ATOM   3582 C C     . ASN   D 2 383 ? 231.645 208.000 236.148 1.00 69.83  ? 395 ASN   A C     1 
ATOM   3583 O O     . ASN   D 2 383 ? 231.789 208.492 237.270 1.00 71.04  ? 395 ASN   A O     1 
ATOM   3584 C CB    . ASN   D 2 383 ? 229.742 206.370 236.074 1.00 62.26  ? 395 ASN   A CB    1 
ATOM   3585 C CG    . ASN   D 2 383 ? 229.144 207.111 237.247 1.00 69.81  ? 395 ASN   A CG    1 
ATOM   3586 O OD1   . ASN   D 2 383 ? 229.676 207.076 238.354 1.00 71.28  ? 395 ASN   A OD1   1 
ATOM   3587 N ND2   . ASN   D 2 383 ? 228.033 207.796 237.008 1.00 76.51  ? 395 ASN   A ND2   1 
ATOM   3588 N N     . THR   D 2 384 ? 231.831 208.689 235.023 1.00 68.70  ? 396 THR   A N     1 
ATOM   3589 C CA    . THR   D 2 384 ? 232.293 210.067 235.046 1.00 66.46  ? 396 THR   A CA    1 
ATOM   3590 C C     . THR   D 2 384 ? 231.217 211.090 234.717 1.00 72.90  ? 396 THR   A C     1 
ATOM   3591 O O     . THR   D 2 384 ? 231.398 212.267 235.044 1.00 79.28  ? 396 THR   A O     1 
ATOM   3592 C CB    . THR   D 2 384 ? 233.466 210.250 234.074 1.00 67.04  ? 396 THR   A CB    1 
ATOM   3593 O OG1   . THR   D 2 384 ? 232.995 210.125 232.727 1.00 74.87  ? 396 THR   A OG1   1 
ATOM   3594 C CG2   . THR   D 2 384 ? 234.535 209.205 234.337 1.00 58.46  ? 396 THR   A CG2   1 
ATOM   3595 N N     . ASN   D 2 385 ? 230.121 210.681 234.084 1.00 70.08  ? 397 ASN   A N     1 
ATOM   3596 C CA    . ASN   D 2 385 ? 228.987 211.567 233.817 1.00 73.07  ? 397 ASN   A CA    1 
ATOM   3597 C C     . ASN   D 2 385 ? 229.387 212.792 232.999 1.00 73.74  ? 397 ASN   A C     1 
ATOM   3598 O O     . ASN   D 2 385 ? 230.410 212.790 232.317 1.00 74.06  ? 397 ASN   A O     1 
ATOM   3599 C CB    . ASN   D 2 385 ? 228.337 212.007 235.132 1.00 70.90  ? 397 ASN   A CB    1 
ATOM   3600 C CG    . ASN   D 2 385 ? 226.827 212.082 235.044 1.00 72.86  ? 397 ASN   A CG    1 
ATOM   3601 O OD1   . ASN   D 2 385 ? 226.264 212.301 233.972 1.00 69.89  ? 397 ASN   A OD1   1 
ATOM   3602 N ND2   . ASN   D 2 385 ? 226.161 211.898 236.177 1.00 67.03  ? 397 ASN   A ND2   1 
ATOM   3603 N N     . THR   D 2 425 ? 236.816 225.933 225.356 1.00 100.69 ? 437 THR   A N     1 
ATOM   3604 C CA    . THR   D 2 425 ? 237.339 225.816 224.001 1.00 107.37 ? 437 THR   A CA    1 
ATOM   3605 C C     . THR   D 2 425 ? 238.635 225.010 224.007 1.00 97.90  ? 437 THR   A C     1 
ATOM   3606 O O     . THR   D 2 425 ? 238.612 223.789 224.147 1.00 90.83  ? 437 THR   A O     1 
ATOM   3607 C CB    . THR   D 2 425 ? 237.589 227.200 223.372 1.00 111.60 ? 437 THR   A CB    1 
ATOM   3608 O OG1   . THR   D 2 425 ? 236.543 228.098 223.762 1.00 104.10 ? 437 THR   A OG1   1 
ATOM   3609 C CG2   . THR   D 2 425 ? 237.613 227.099 221.853 1.00 112.58 ? 437 THR   A CG2   1 
ATOM   3610 N N     . SER   D 2 426 ? 239.765 225.698 223.855 1.00 99.46  ? 438 SER   A N     1 
ATOM   3611 C CA    . SER   D 2 426 ? 241.070 225.059 223.923 1.00 89.77  ? 438 SER   A CA    1 
ATOM   3612 C C     . SER   D 2 426 ? 241.631 225.016 225.336 1.00 82.59  ? 438 SER   A C     1 
ATOM   3613 O O     . SER   D 2 426 ? 242.684 224.408 225.552 1.00 78.61  ? 438 SER   A O     1 
ATOM   3614 C CB    . SER   D 2 426 ? 242.060 225.776 223.000 1.00 87.36  ? 438 SER   A CB    1 
ATOM   3615 O OG    . SER   D 2 426 ? 243.229 225.001 222.810 1.00 81.04  ? 438 SER   A OG    1 
ATOM   3616 N N     . ASP   D 2 427 ? 240.960 225.648 226.295 1.00 83.50  ? 439 ASP   A N     1 
ATOM   3617 C CA    . ASP   D 2 427 ? 241.325 225.566 227.707 1.00 74.72  ? 439 ASP   A CA    1 
ATOM   3618 C C     . ASP   D 2 427 ? 240.368 224.576 228.356 1.00 71.65  ? 439 ASP   A C     1 
ATOM   3619 O O     . ASP   D 2 427 ? 239.292 224.939 228.830 1.00 69.44  ? 439 ASP   A O     1 
ATOM   3620 C CB    . ASP   D 2 427 ? 241.262 226.934 228.374 1.00 74.53  ? 439 ASP   A CB    1 
ATOM   3621 C CG    . ASP   D 2 427 ? 242.012 226.973 229.685 1.00 75.85  ? 439 ASP   A CG    1 
ATOM   3622 O OD1   . ASP   D 2 427 ? 243.039 226.274 229.803 1.00 71.66  ? 439 ASP   A OD1   1 
ATOM   3623 O OD2   . ASP   D 2 427 ? 241.574 227.699 230.600 1.00 81.42  ? 439 ASP   A OD2   1 
ATOM   3624 N N     . MET   D 2 428 ? 240.766 223.309 228.373 1.00 66.52  ? 440 MET   A N     1 
ATOM   3625 C CA    . MET   D 2 428 ? 239.916 222.269 228.933 1.00 59.14  ? 440 MET   A CA    1 
ATOM   3626 C C     . MET   D 2 428 ? 240.047 222.157 230.443 1.00 57.69  ? 440 MET   A C     1 
ATOM   3627 O O     . MET   D 2 428 ? 239.358 221.329 231.045 1.00 56.86  ? 440 MET   A O     1 
ATOM   3628 C CB    . MET   D 2 428 ? 240.231 220.926 228.274 1.00 53.50  ? 440 MET   A CB    1 
ATOM   3629 C CG    . MET   D 2 428 ? 240.494 221.036 226.787 1.00 62.39  ? 440 MET   A CG    1 
ATOM   3630 S SD    . MET   D 2 428 ? 239.004 221.047 225.774 1.00 82.64  ? 440 MET   A SD    1 
ATOM   3631 C CE    . MET   D 2 428 ? 238.108 219.659 226.445 1.00 65.39  ? 440 MET   A CE    1 
ATOM   3632 N N     . ARG   D 2 429 ? 240.912 222.965 231.063 1.00 60.46  ? 441 ARG   A N     1 
ATOM   3633 C CA    . ARG   D 2 429 ? 240.998 222.981 232.519 1.00 53.70  ? 441 ARG   A CA    1 
ATOM   3634 C C     . ARG   D 2 429 ? 239.691 223.449 233.142 1.00 54.87  ? 441 ARG   A C     1 
ATOM   3635 O O     . ARG   D 2 429 ? 239.228 222.876 234.133 1.00 57.72  ? 441 ARG   A O     1 
ATOM   3636 C CB    . ARG   D 2 429 ? 242.149 223.877 232.970 1.00 49.81  ? 441 ARG   A CB    1 
ATOM   3637 C CG    . ARG   D 2 429 ? 243.493 223.193 232.970 1.00 54.96  ? 441 ARG   A CG    1 
ATOM   3638 C CD    . ARG   D 2 429 ? 244.611 224.199 233.111 1.00 54.00  ? 441 ARG   A CD    1 
ATOM   3639 N NE    . ARG   D 2 429 ? 244.894 224.498 234.507 1.00 51.29  ? 441 ARG   A NE    1 
ATOM   3640 C CZ    . ARG   D 2 429 ? 246.091 224.394 235.064 1.00 51.59  ? 441 ARG   A CZ    1 
ATOM   3641 N NH1   . ARG   D 2 429 ? 247.144 224.000 234.369 1.00 52.75  ? 441 ARG   A NH1   1 
ATOM   3642 N NH2   . ARG   D 2 429 ? 246.236 224.694 236.351 1.00 54.23  ? 441 ARG   A NH2   1 
ATOM   3643 N N     . THR   D 2 430 ? 239.086 224.496 232.579 1.00 54.28  ? 442 THR   A N     1 
ATOM   3644 C CA    . THR   D 2 430 ? 237.811 224.977 233.097 1.00 53.14  ? 442 THR   A CA    1 
ATOM   3645 C C     . THR   D 2 430 ? 236.728 223.916 232.953 1.00 50.44  ? 442 THR   A C     1 
ATOM   3646 O O     . THR   D 2 430 ? 235.925 223.708 233.870 1.00 49.37  ? 442 THR   A O     1 
ATOM   3647 C CB    . THR   D 2 430 ? 237.414 226.270 232.384 1.00 54.50  ? 442 THR   A CB    1 
ATOM   3648 O OG1   . THR   D 2 430 ? 238.105 227.372 232.983 1.00 56.22  ? 442 THR   A OG1   1 
ATOM   3649 C CG2   . THR   D 2 430 ? 235.917 226.511 232.479 1.00 56.90  ? 442 THR   A CG2   1 
ATOM   3650 N N     . GLU   D 2 431 ? 236.706 223.217 231.816 1.00 50.86  ? 443 GLU   A N     1 
ATOM   3651 C CA    . GLU   D 2 431 ? 235.728 222.154 231.616 1.00 51.45  ? 443 GLU   A CA    1 
ATOM   3652 C C     . GLU   D 2 431 ? 235.942 221.012 232.601 1.00 50.03  ? 443 GLU   A C     1 
ATOM   3653 O O     . GLU   D 2 431 ? 234.978 220.465 233.151 1.00 52.58  ? 443 GLU   A O     1 
ATOM   3654 C CB    . GLU   D 2 431 ? 235.799 221.645 230.178 1.00 53.77  ? 443 GLU   A CB    1 
ATOM   3655 C CG    . GLU   D 2 431 ? 235.293 220.229 229.990 1.00 55.22  ? 443 GLU   A CG    1 
ATOM   3656 C CD    . GLU   D 2 431 ? 233.851 220.188 229.546 1.00 58.27  ? 443 GLU   A CD    1 
ATOM   3657 O OE1   . GLU   D 2 431 ? 233.143 221.195 229.741 1.00 61.81  ? 443 GLU   A OE1   1 
ATOM   3658 O OE2   . GLU   D 2 431 ? 233.426 219.150 228.999 1.00 62.98  ? 443 GLU   A OE2   1 
ATOM   3659 N N     . ILE   D 2 432 ? 237.201 220.640 232.842 1.00 48.72  ? 444 ILE   A N     1 
ATOM   3660 C CA    . ILE   D 2 432 ? 237.488 219.584 233.806 1.00 49.50  ? 444 ILE   A CA    1 
ATOM   3661 C C     . ILE   D 2 432 ? 237.033 220.003 235.196 1.00 47.36  ? 444 ILE   A C     1 
ATOM   3662 O O     . ILE   D 2 432 ? 236.407 219.222 235.922 1.00 45.38  ? 444 ILE   A O     1 
ATOM   3663 C CB    . ILE   D 2 432 ? 238.986 219.229 233.782 1.00 48.69  ? 444 ILE   A CB    1 
ATOM   3664 C CG1   . ILE   D 2 432 ? 239.284 218.244 232.657 1.00 45.47  ? 444 ILE   A CG1   1 
ATOM   3665 C CG2   . ILE   D 2 432 ? 239.418 218.626 235.105 1.00 53.26  ? 444 ILE   A CG2   1 
ATOM   3666 C CD1   . ILE   D 2 432 ? 240.751 217.958 232.487 1.00 49.12  ? 444 ILE   A CD1   1 
ATOM   3667 N N     . ILE   D 2 433 ? 237.331 221.245 235.581 1.00 48.49  ? 445 ILE   A N     1 
ATOM   3668 C CA    . ILE   D 2 433 ? 236.944 221.741 236.898 1.00 48.30  ? 445 ILE   A CA    1 
ATOM   3669 C C     . ILE   D 2 433 ? 235.430 221.737 237.042 1.00 49.37  ? 445 ILE   A C     1 
ATOM   3670 O O     . ILE   D 2 433 ? 234.894 221.370 238.092 1.00 50.76  ? 445 ILE   A O     1 
ATOM   3671 C CB    . ILE   D 2 433 ? 237.536 223.142 237.134 1.00 48.74  ? 445 ILE   A CB    1 
ATOM   3672 C CG1   . ILE   D 2 433 ? 239.049 223.054 237.322 1.00 48.65  ? 445 ILE   A CG1   1 
ATOM   3673 C CG2   . ILE   D 2 433 ? 236.885 223.806 238.335 1.00 55.08  ? 445 ILE   A CG2   1 
ATOM   3674 C CD1   . ILE   D 2 433 ? 239.653 224.258 237.999 1.00 48.63  ? 445 ILE   A CD1   1 
ATOM   3675 N N     . ARG   D 2 434 ? 234.719 222.134 235.987 1.00 50.50  ? 446 ARG   A N     1 
ATOM   3676 C CA    . ARG   D 2 434 ? 233.260 222.102 236.014 1.00 51.79  ? 446 ARG   A CA    1 
ATOM   3677 C C     . ARG   D 2 434 ? 232.741 220.676 236.173 1.00 50.50  ? 446 ARG   A C     1 
ATOM   3678 O O     . ARG   D 2 434 ? 231.818 220.422 236.961 1.00 53.26  ? 446 ARG   A O     1 
ATOM   3679 C CB    . ARG   D 2 434 ? 232.718 222.750 234.740 1.00 50.26  ? 446 ARG   A CB    1 
ATOM   3680 C CG    . ARG   D 2 434 ? 231.246 222.537 234.488 1.00 51.94  ? 446 ARG   A CG    1 
ATOM   3681 C CD    . ARG   D 2 434 ? 230.803 223.266 233.230 1.00 46.64  ? 446 ARG   A CD    1 
ATOM   3682 N NE    . ARG   D 2 434 ? 230.984 222.459 232.029 1.00 52.80  ? 446 ARG   A NE    1 
ATOM   3683 C CZ    . ARG   D 2 434 ? 230.262 221.389 231.724 1.00 56.86  ? 446 ARG   A CZ    1 
ATOM   3684 N NH1   . ARG   D 2 434 ? 229.289 220.963 232.511 1.00 60.08  ? 446 ARG   A NH1   1 
ATOM   3685 N NH2   . ARG   D 2 434 ? 230.522 220.731 230.600 1.00 57.50  ? 446 ARG   A NH2   1 
ATOM   3686 N N     . LEU   D 2 435 ? 233.343 219.728 235.450 1.00 48.80  ? 447 LEU   A N     1 
ATOM   3687 C CA    . LEU   D 2 435 ? 232.929 218.332 235.554 1.00 52.14  ? 447 LEU   A CA    1 
ATOM   3688 C C     . LEU   D 2 435 ? 233.129 217.794 236.966 1.00 50.74  ? 447 LEU   A C     1 
ATOM   3689 O O     . LEU   D 2 435 ? 232.263 217.088 237.496 1.00 48.91  ? 447 LEU   A O     1 
ATOM   3690 C CB    . LEU   D 2 435 ? 233.700 217.479 234.547 1.00 49.99  ? 447 LEU   A CB    1 
ATOM   3691 C CG    . LEU   D 2 435 ? 233.267 217.537 233.084 1.00 49.39  ? 447 LEU   A CG    1 
ATOM   3692 C CD1   . LEU   D 2 435 ? 234.349 216.953 232.199 1.00 44.85  ? 447 LEU   A CD1   1 
ATOM   3693 C CD2   . LEU   D 2 435 ? 231.957 216.805 232.882 1.00 56.40  ? 447 LEU   A CD2   1 
ATOM   3694 N N     . MET   D 2 436 ? 234.270 218.104 237.587 1.00 50.95  ? 448 MET   A N     1 
ATOM   3695 C CA    . MET   D 2 436 ? 234.504 217.640 238.954 1.00 52.43  ? 448 MET   A CA    1 
ATOM   3696 C C     . MET   D 2 436 ? 233.619 218.366 239.959 1.00 53.89  ? 448 MET   A C     1 
ATOM   3697 O O     . MET   D 2 436 ? 233.233 217.781 240.977 1.00 53.30  ? 448 MET   A O     1 
ATOM   3698 C CB    . MET   D 2 436 ? 235.976 217.793 239.342 1.00 52.78  ? 448 MET   A CB    1 
ATOM   3699 C CG    . MET   D 2 436 ? 236.955 217.513 238.228 1.00 52.64  ? 448 MET   A CG    1 
ATOM   3700 S SD    . MET   D 2 436 ? 238.663 217.930 238.616 1.00 60.57  ? 448 MET   A SD    1 
ATOM   3701 C CE    . MET   D 2 436 ? 238.640 217.850 240.397 1.00 50.96  ? 448 MET   A CE    1 
ATOM   3702 N N     . GLU   D 2 437 ? 233.294 219.632 239.701 1.00 53.22  ? 449 GLU   A N     1 
ATOM   3703 C CA    . GLU   D 2 437 ? 232.401 220.360 240.591 1.00 54.15  ? 449 GLU   A CA    1 
ATOM   3704 C C     . GLU   D 2 437 ? 230.996 219.783 240.557 1.00 55.85  ? 449 GLU   A C     1 
ATOM   3705 O O     . GLU   D 2 437 ? 230.292 219.810 241.573 1.00 57.41  ? 449 GLU   A O     1 
ATOM   3706 C CB    . GLU   D 2 437 ? 232.373 221.837 240.213 1.00 57.34  ? 449 GLU   A CB    1 
ATOM   3707 C CG    . GLU   D 2 437 ? 231.933 222.750 241.334 1.00 63.70  ? 449 GLU   A CG    1 
ATOM   3708 C CD    . GLU   D 2 437 ? 233.102 223.303 242.115 1.00 76.65  ? 449 GLU   A CD    1 
ATOM   3709 O OE1   . GLU   D 2 437 ? 233.952 223.984 241.507 1.00 76.18  ? 449 GLU   A OE1   1 
ATOM   3710 O OE2   . GLU   D 2 437 ? 233.173 223.055 243.335 1.00 86.57  ? 449 GLU   A OE2   1 
ATOM   3711 N N     . SER   D 2 438 ? 230.568 219.268 239.403 1.00 54.93  ? 450 SER   A N     1 
ATOM   3712 C CA    . SER   D 2 438 ? 229.254 218.639 239.328 1.00 53.48  ? 450 SER   A CA    1 
ATOM   3713 C C     . SER   D 2 438 ? 229.190 217.355 240.148 1.00 53.95  ? 450 SER   A C     1 
ATOM   3714 O O     . SER   D 2 438 ? 228.136 217.034 240.708 1.00 58.89  ? 450 SER   A O     1 
ATOM   3715 C CB    . SER   D 2 438 ? 228.892 218.354 237.874 1.00 55.13  ? 450 SER   A CB    1 
ATOM   3716 O OG    . SER   D 2 438 ? 229.328 217.064 237.488 1.00 58.79  ? 450 SER   A OG    1 
ATOM   3717 N N     . ALA   D 2 439 ? 230.292 216.616 240.234 1.00 53.98  ? 451 ALA   A N     1 
ATOM   3718 C CA    . ALA   D 2 439 ? 230.291 215.323 240.905 1.00 53.14  ? 451 ALA   A CA    1 
ATOM   3719 C C     . ALA   D 2 439 ? 230.170 215.475 242.417 1.00 56.81  ? 451 ALA   A C     1 
ATOM   3720 O O     . ALA   D 2 439 ? 230.636 216.451 243.008 1.00 60.99  ? 451 ALA   A O     1 
ATOM   3721 C CB    . ALA   D 2 439 ? 231.562 214.548 240.566 1.00 49.68  ? 451 ALA   A CB    1 
ATOM   3722 N N     . ARG   D 2 440 ? 229.538 214.486 243.043 1.00 55.51  ? 452 ARG   A N     1 
ATOM   3723 C CA    . ARG   D 2 440 ? 229.374 214.428 244.486 1.00 56.09  ? 452 ARG   A CA    1 
ATOM   3724 C C     . ARG   D 2 440 ? 229.819 213.068 245.001 1.00 57.51  ? 452 ARG   A C     1 
ATOM   3725 O O     . ARG   D 2 440 ? 229.682 212.060 244.301 1.00 57.38  ? 452 ARG   A O     1 
ATOM   3726 C CB    . ARG   D 2 440 ? 227.913 214.672 244.889 1.00 53.27  ? 452 ARG   A CB    1 
ATOM   3727 C CG    . ARG   D 2 440 ? 227.250 215.805 244.140 1.00 53.07  ? 452 ARG   A CG    1 
ATOM   3728 C CD    . ARG   D 2 440 ? 227.142 217.044 245.000 1.00 52.31  ? 452 ARG   A CD    1 
ATOM   3729 N NE    . ARG   D 2 440 ? 227.019 218.250 244.192 1.00 60.19  ? 452 ARG   A NE    1 
ATOM   3730 C CZ    . ARG   D 2 440 ? 227.481 219.438 244.550 1.00 65.34  ? 452 ARG   A CZ    1 
ATOM   3731 N NH1   . ARG   D 2 440 ? 228.081 219.623 245.713 1.00 63.60  ? 452 ARG   A NH1   1 
ATOM   3732 N NH2   . ARG   D 2 440 ? 227.329 220.469 243.725 1.00 68.76  ? 452 ARG   A NH2   1 
ATOM   3733 N N     . PRO   D 2 441 ? 230.348 213.005 246.226 1.00 59.54  ? 453 PRO   A N     1 
ATOM   3734 C CA    . PRO   D 2 441 ? 230.804 211.715 246.758 1.00 58.64  ? 453 PRO   A CA    1 
ATOM   3735 C C     . PRO   D 2 441 ? 229.659 210.865 247.276 1.00 58.76  ? 453 PRO   A C     1 
ATOM   3736 O O     . PRO   D 2 441 ? 229.760 210.245 248.339 1.00 67.13  ? 453 PRO   A O     1 
ATOM   3737 C CB    . PRO   D 2 441 ? 231.749 212.126 247.890 1.00 63.71  ? 453 PRO   A CB    1 
ATOM   3738 C CG    . PRO   D 2 441 ? 231.203 213.422 248.357 1.00 59.45  ? 453 PRO   A CG    1 
ATOM   3739 C CD    . PRO   D 2 441 ? 230.664 214.118 247.137 1.00 59.99  ? 453 PRO   A CD    1 
ATOM   3740 N N     . GLU   D 2 442 ? 228.566 210.827 246.523 1.00 58.16  ? 454 GLU   A N     1 
ATOM   3741 C CA    . GLU   D 2 442 ? 227.420 210.000 246.859 1.00 55.70  ? 454 GLU   A CA    1 
ATOM   3742 C C     . GLU   D 2 442 ? 226.834 209.306 245.641 1.00 54.39  ? 454 GLU   A C     1 
ATOM   3743 O O     . GLU   D 2 442 ? 225.870 208.550 245.790 1.00 49.69  ? 454 GLU   A O     1 
ATOM   3744 C CB    . GLU   D 2 442 ? 226.332 210.841 247.546 1.00 51.77  ? 454 GLU   A CB    1 
ATOM   3745 C CG    . GLU   D 2 442 ? 226.702 211.314 248.939 1.00 52.13  ? 454 GLU   A CG    1 
ATOM   3746 C CD    . GLU   D 2 442 ? 226.955 212.807 249.004 1.00 56.65  ? 454 GLU   A CD    1 
ATOM   3747 O OE1   . GLU   D 2 442 ? 226.729 213.500 247.992 1.00 53.87  ? 454 GLU   A OE1   1 
ATOM   3748 O OE2   . GLU   D 2 442 ? 227.379 213.289 250.073 1.00 60.36  ? 454 GLU   A OE2   1 
ATOM   3749 N N     . ASP   D 2 443 ? 227.375 209.544 244.450 1.00 59.66  ? 455 ASP   A N     1 
ATOM   3750 C CA    . ASP   D 2 443 ? 226.888 208.885 243.249 1.00 58.03  ? 455 ASP   A CA    1 
ATOM   3751 C C     . ASP   D 2 443 ? 227.220 207.403 243.290 1.00 56.95  ? 455 ASP   A C     1 
ATOM   3752 O O     . ASP   D 2 443 ? 228.282 207.000 243.772 1.00 55.86  ? 455 ASP   A O     1 
ATOM   3753 C CB    . ASP   D 2 443 ? 227.503 209.514 242.001 1.00 58.73  ? 455 ASP   A CB    1 
ATOM   3754 C CG    . ASP   D 2 443 ? 227.521 211.021 242.057 1.00 67.36  ? 455 ASP   A CG    1 
ATOM   3755 O OD1   . ASP   D 2 443 ? 226.478 211.617 242.395 1.00 76.62  ? 455 ASP   A OD1   1 
ATOM   3756 O OD2   . ASP   D 2 443 ? 228.576 211.613 241.753 1.00 66.16  ? 455 ASP   A OD2   1 
ATOM   3757 N N     . VAL   D 2 444 ? 226.306 206.593 242.779 1.00 57.01  ? 456 VAL   A N     1 
ATOM   3758 C CA    . VAL   D 2 444 ? 226.499 205.152 242.716 1.00 55.94  ? 456 VAL   A CA    1 
ATOM   3759 C C     . VAL   D 2 444 ? 227.036 204.797 241.336 1.00 59.13  ? 456 VAL   A C     1 
ATOM   3760 O O     . VAL   D 2 444 ? 226.411 205.101 240.315 1.00 64.07  ? 456 VAL   A O     1 
ATOM   3761 C CB    . VAL   D 2 444 ? 225.194 204.402 243.019 1.00 58.03  ? 456 VAL   A CB    1 
ATOM   3762 C CG1   . VAL   D 2 444 ? 224.959 204.357 244.514 1.00 52.48  ? 456 VAL   A CG1   1 
ATOM   3763 C CG2   . VAL   D 2 444 ? 224.023 205.074 242.328 1.00 59.69  ? 456 VAL   A CG2   1 
ATOM   3764 N N     . SER   D 2 445 ? 228.205 204.171 241.305 1.00 56.27  ? 457 SER   A N     1 
ATOM   3765 C CA    . SER   D 2 445 ? 228.773 203.629 240.085 1.00 58.08  ? 457 SER   A CA    1 
ATOM   3766 C C     . SER   D 2 445 ? 228.519 202.127 240.056 1.00 55.61  ? 457 SER   A C     1 
ATOM   3767 O O     . SER   D 2 445 ? 227.889 201.572 240.955 1.00 59.99  ? 457 SER   A O     1 
ATOM   3768 C CB    . SER   D 2 445 ? 230.263 203.953 239.999 1.00 57.92  ? 457 SER   A CB    1 
ATOM   3769 O OG    . SER   D 2 445 ? 230.897 203.685 241.233 1.00 64.40  ? 457 SER   A OG    1 
ATOM   3770 N N     . PHE   D 2 446 ? 228.998 201.469 239.002 1.00 50.58  ? 458 PHE   A N     1 
ATOM   3771 C CA    . PHE   D 2 446 ? 228.886 200.015 238.857 1.00 56.29  ? 458 PHE   A CA    1 
ATOM   3772 C C     . PHE   D 2 446 ? 227.482 199.526 239.212 1.00 57.62  ? 458 PHE   A C     1 
ATOM   3773 O O     . PHE   D 2 446 ? 227.303 198.587 239.989 1.00 61.67  ? 458 PHE   A O     1 
ATOM   3774 C CB    . PHE   D 2 446 ? 229.932 199.297 239.711 1.00 55.72  ? 458 PHE   A CB    1 
ATOM   3775 C CG    . PHE   D 2 446 ? 231.337 199.777 239.497 1.00 53.35  ? 458 PHE   A CG    1 
ATOM   3776 C CD1   . PHE   D 2 446 ? 232.030 199.446 238.347 1.00 54.83  ? 458 PHE   A CD1   1 
ATOM   3777 C CD2   . PHE   D 2 446 ? 231.973 200.540 240.457 1.00 51.47  ? 458 PHE   A CD2   1 
ATOM   3778 C CE1   . PHE   D 2 446 ? 233.326 199.880 238.155 1.00 53.99  ? 458 PHE   A CE1   1 
ATOM   3779 C CE2   . PHE   D 2 446 ? 233.266 200.976 240.270 1.00 51.33  ? 458 PHE   A CE2   1 
ATOM   3780 C CZ    . PHE   D 2 446 ? 233.944 200.644 239.118 1.00 52.91  ? 458 PHE   A CZ    1 
ATOM   3781 N N     . GLN   D 2 447 ? 226.477 200.188 238.650 1.00 53.06  ? 459 GLN   A N     1 
ATOM   3782 C CA    . GLN   D 2 447 ? 225.100 199.912 239.036 1.00 52.79  ? 459 GLN   A CA    1 
ATOM   3783 C C     . GLN   D 2 447 ? 224.695 198.498 238.641 1.00 52.91  ? 459 GLN   A C     1 
ATOM   3784 O O     . GLN   D 2 447 ? 225.000 198.029 237.543 1.00 53.53  ? 459 GLN   A O     1 
ATOM   3785 C CB    . GLN   D 2 447 ? 224.154 200.926 238.398 1.00 56.45  ? 459 GLN   A CB    1 
ATOM   3786 C CG    . GLN   D 2 447 ? 222.715 200.793 238.853 1.00 52.72  ? 459 GLN   A CG    1 
ATOM   3787 C CD    . GLN   D 2 447 ? 222.227 202.021 239.585 1.00 61.02  ? 459 GLN   A CD    1 
ATOM   3788 O OE1   . GLN   D 2 447 ? 222.936 203.021 239.683 1.00 65.89  ? 459 GLN   A OE1   1 
ATOM   3789 N NE2   . GLN   D 2 447 ? 221.010 201.953 240.107 1.00 63.37  ? 459 GLN   A NE2   1 
ATOM   3790 N N     . GLY   D 2 448 ? 224.000 197.820 239.550 1.00 52.88  ? 460 GLY   A N     1 
ATOM   3791 C CA    . GLY   D 2 448 ? 223.541 196.472 239.299 1.00 50.22  ? 460 GLY   A CA    1 
ATOM   3792 C C     . GLY   D 2 448 ? 224.599 195.403 239.416 1.00 51.94  ? 460 GLY   A C     1 
ATOM   3793 O O     . GLY   D 2 448 ? 224.354 194.266 239.000 1.00 56.97  ? 460 GLY   A O     1 
ATOM   3794 N N     . ARG   D 2 449 ? 225.766 195.727 239.959 1.00 51.29  ? 461 ARG   A N     1 
ATOM   3795 C CA    . ARG   D 2 449 ? 226.846 194.770 240.140 1.00 51.09  ? 461 ARG   A CA    1 
ATOM   3796 C C     . ARG   D 2 449 ? 227.049 194.511 241.624 1.00 55.75  ? 461 ARG   A C     1 
ATOM   3797 O O     . ARG   D 2 449 ? 227.011 195.439 242.436 1.00 60.56  ? 461 ARG   A O     1 
ATOM   3798 C CB    . ARG   D 2 449 ? 228.145 195.277 239.514 1.00 47.04  ? 461 ARG   A CB    1 
ATOM   3799 C CG    . ARG   D 2 449 ? 227.986 195.791 238.101 1.00 51.48  ? 461 ARG   A CG    1 
ATOM   3800 C CD    . ARG   D 2 449 ? 229.106 195.296 237.210 1.00 54.16  ? 461 ARG   A CD    1 
ATOM   3801 N NE    . ARG   D 2 449 ? 228.927 195.724 235.829 1.00 55.44  ? 461 ARG   A NE    1 
ATOM   3802 C CZ    . ARG   D 2 449 ? 228.179 195.088 234.940 1.00 60.73  ? 461 ARG   A CZ    1 
ATOM   3803 N NH1   . ARG   D 2 449 ? 227.530 193.979 235.251 1.00 59.21  ? 461 ARG   A NH1   1 
ATOM   3804 N NH2   . ARG   D 2 449 ? 228.080 195.575 233.708 1.00 71.19  ? 461 ARG   A NH2   1 
ATOM   3805 N N     . GLY   D 2 450 ? 227.258 193.247 241.974 1.00 54.02  ? 462 GLY   A N     1 
ATOM   3806 C CA    . GLY   D 2 450 ? 227.402 192.885 243.367 1.00 52.94  ? 462 GLY   A CA    1 
ATOM   3807 C C     . GLY   D 2 450 ? 228.510 191.892 243.638 1.00 53.10  ? 462 GLY   A C     1 
ATOM   3808 O O     . GLY   D 2 450 ? 229.349 191.631 242.772 1.00 59.48  ? 462 GLY   A O     1 
ATOM   3809 N N     . VAL   D 2 451 ? 228.520 191.333 244.843 1.00 50.37  ? 463 VAL   A N     1 
ATOM   3810 C CA    . VAL   D 2 451 ? 229.515 190.357 245.262 1.00 51.96  ? 463 VAL   A CA    1 
ATOM   3811 C C     . VAL   D 2 451 ? 228.871 188.981 245.243 1.00 54.80  ? 463 VAL   A C     1 
ATOM   3812 O O     . VAL   D 2 451 ? 227.732 188.810 245.692 1.00 59.33  ? 463 VAL   A O     1 
ATOM   3813 C CB    . VAL   D 2 451 ? 230.080 190.683 246.658 1.00 54.10  ? 463 VAL   A CB    1 
ATOM   3814 C CG1   . VAL   D 2 451 ? 231.047 191.842 246.574 1.00 56.01  ? 463 VAL   A CG1   1 
ATOM   3815 C CG2   . VAL   D 2 451 ? 228.958 191.000 247.618 1.00 54.72  ? 463 VAL   A CG2   1 
ATOM   3816 N N     . PHE   D 2 452 ? 229.591 188.005 244.712 1.00 52.01  ? 464 PHE   A N     1 
ATOM   3817 C CA    . PHE   D 2 452 ? 229.059 186.666 244.527 1.00 51.29  ? 464 PHE   A CA    1 
ATOM   3818 C C     . PHE   D 2 452 ? 229.605 185.720 245.586 1.00 52.79  ? 464 PHE   A C     1 
ATOM   3819 O O     . PHE   D 2 452 ? 230.752 185.838 246.023 1.00 53.59  ? 464 PHE   A O     1 
ATOM   3820 C CB    . PHE   D 2 452 ? 229.396 186.131 243.135 1.00 53.55  ? 464 PHE   A CB    1 
ATOM   3821 C CG    . PHE   D 2 452 ? 229.162 187.117 242.032 1.00 53.27  ? 464 PHE   A CG    1 
ATOM   3822 C CD1   . PHE   D 2 452 ? 230.156 187.999 241.650 1.00 54.49  ? 464 PHE   A CD1   1 
ATOM   3823 C CD2   . PHE   D 2 452 ? 227.950 187.161 241.374 1.00 53.81  ? 464 PHE   A CD2   1 
ATOM   3824 C CE1   . PHE   D 2 452 ? 229.944 188.905 240.637 1.00 54.84  ? 464 PHE   A CE1   1 
ATOM   3825 C CE2   . PHE   D 2 452 ? 227.734 188.065 240.358 1.00 55.09  ? 464 PHE   A CE2   1 
ATOM   3826 C CZ    . PHE   D 2 452 ? 228.733 188.938 239.990 1.00 53.63  ? 464 PHE   A CZ    1 
ATOM   3827 N N     . GLU   D 2 453 ? 228.765 184.778 245.996 1.00 54.86  ? 465 GLU   A N     1 
ATOM   3828 C CA    . GLU   D 2 453 ? 229.199 183.741 246.912 1.00 53.08  ? 465 GLU   A CA    1 
ATOM   3829 C C     . GLU   D 2 453 ? 230.193 182.813 246.221 1.00 54.83  ? 465 GLU   A C     1 
ATOM   3830 O O     . GLU   D 2 453 ? 230.239 182.709 244.993 1.00 57.77  ? 465 GLU   A O     1 
ATOM   3831 C CB    . GLU   D 2 453 ? 228.001 182.951 247.429 1.00 48.28  ? 465 GLU   A CB    1 
ATOM   3832 C CG    . GLU   D 2 453 ? 227.048 183.778 248.262 1.00 56.77  ? 465 GLU   A CG    1 
ATOM   3833 C CD    . GLU   D 2 453 ? 226.462 182.999 249.415 1.00 69.79  ? 465 GLU   A CD    1 
ATOM   3834 O OE1   . GLU   D 2 453 ? 227.071 183.000 250.503 1.00 73.67  ? 465 GLU   A OE1   1 
ATOM   3835 O OE2   . GLU   D 2 453 ? 225.391 182.385 249.234 1.00 80.72  ? 465 GLU   A OE2   1 
ATOM   3836 N N     . LEU   D 2 454 ? 231.003 182.135 247.036 1.00 54.20  ? 466 LEU   A N     1 
ATOM   3837 C CA    . LEU   D 2 454 ? 232.071 181.305 246.490 1.00 53.19  ? 466 LEU   A CA    1 
ATOM   3838 C C     . LEU   D 2 454 ? 231.522 180.134 245.685 1.00 52.99  ? 466 LEU   A C     1 
ATOM   3839 O O     . LEU   D 2 454 ? 232.196 179.638 244.776 1.00 54.51  ? 466 LEU   A O     1 
ATOM   3840 C CB    . LEU   D 2 454 ? 232.973 180.807 247.618 1.00 53.59  ? 466 LEU   A CB    1 
ATOM   3841 C CG    . LEU   D 2 454 ? 234.281 181.572 247.833 1.00 51.87  ? 466 LEU   A CG    1 
ATOM   3842 C CD1   . LEU   D 2 454 ? 235.236 181.325 246.683 1.00 48.89  ? 466 LEU   A CD1   1 
ATOM   3843 C CD2   . LEU   D 2 454 ? 234.026 183.056 248.001 1.00 50.79  ? 466 LEU   A CD2   1 
ATOM   3844 N N     . SER   D 2 455 ? 230.310 179.680 245.997 1.00 50.10  ? 467 SER   A N     1 
ATOM   3845 C CA    . SER   D 2 455 ? 229.699 178.599 245.235 1.00 48.30  ? 467 SER   A CA    1 
ATOM   3846 C C     . SER   D 2 455 ? 229.163 179.062 243.889 1.00 54.07  ? 467 SER   A C     1 
ATOM   3847 O O     . SER   D 2 455 ? 228.940 178.230 243.004 1.00 56.57  ? 467 SER   A O     1 
ATOM   3848 C CB    . SER   D 2 455 ? 228.572 177.962 246.045 1.00 50.05  ? 467 SER   A CB    1 
ATOM   3849 O OG    . SER   D 2 455 ? 228.992 177.702 247.371 1.00 55.58  ? 467 SER   A OG    1 
ATOM   3850 N N     . ASP   D 2 456 ? 228.959 180.367 243.715 1.00 58.82  ? 468 ASP   A N     1 
ATOM   3851 C CA    . ASP   D 2 456 ? 228.415 180.927 242.479 1.00 57.16  ? 468 ASP   A CA    1 
ATOM   3852 C C     . ASP   D 2 456 ? 229.566 181.131 241.499 1.00 59.59  ? 468 ASP   A C     1 
ATOM   3853 O O     . ASP   D 2 456 ? 230.065 182.239 241.288 1.00 66.92  ? 468 ASP   A O     1 
ATOM   3854 C CB    . ASP   D 2 456 ? 227.674 182.225 242.770 1.00 51.89  ? 468 ASP   A CB    1 
ATOM   3855 C CG    . ASP   D 2 456 ? 226.831 182.686 241.608 1.00 59.65  ? 468 ASP   A CG    1 
ATOM   3856 O OD1   . ASP   D 2 456 ? 226.772 181.969 240.590 1.00 67.22  ? 468 ASP   A OD1   1 
ATOM   3857 O OD2   . ASP   D 2 456 ? 226.219 183.768 241.716 1.00 63.52  ? 468 ASP   A OD2   1 
ATOM   3858 N N     . GLU   D 2 457 ? 229.995 180.024 240.891 1.00 56.61  ? 469 GLU   A N     1 
ATOM   3859 C CA    . GLU   D 2 457 ? 231.150 180.064 240.001 1.00 60.52  ? 469 GLU   A CA    1 
ATOM   3860 C C     . GLU   D 2 457 ? 230.879 180.914 238.767 1.00 62.45  ? 469 GLU   A C     1 
ATOM   3861 O O     . GLU   D 2 457 ? 231.764 181.638 238.299 1.00 62.10  ? 469 GLU   A O     1 
ATOM   3862 C CB    . GLU   D 2 457 ? 231.545 178.645 239.597 1.00 60.55  ? 469 GLU   A CB    1 
ATOM   3863 C CG    . GLU   D 2 457 ? 231.481 177.644 240.733 1.00 64.04  ? 469 GLU   A CG    1 
ATOM   3864 C CD    . GLU   D 2 457 ? 232.791 176.921 240.944 1.00 73.34  ? 469 GLU   A CD    1 
ATOM   3865 O OE1   . GLU   D 2 457 ? 233.609 176.889 240.003 1.00 75.50  ? 469 GLU   A OE1   1 
ATOM   3866 O OE2   . GLU   D 2 457 ? 233.004 176.384 242.049 1.00 80.78  ? 469 GLU   A OE2   1 
ATOM   3867 N N     . LYS   D 2 458 ? 229.666 180.842 238.227 1.00 61.85  ? 470 LYS   A N     1 
ATOM   3868 C CA    . LYS   D 2 458 ? 229.343 181.523 236.981 1.00 63.54  ? 470 LYS   A CA    1 
ATOM   3869 C C     . LYS   D 2 458 ? 228.949 182.979 237.178 1.00 63.82  ? 470 LYS   A C     1 
ATOM   3870 O O     . LYS   D 2 458 ? 228.673 183.661 236.186 1.00 67.52  ? 470 LYS   A O     1 
ATOM   3871 C CB    . LYS   D 2 458 ? 228.220 180.781 236.257 1.00 63.52  ? 470 LYS   A CB    1 
ATOM   3872 C CG    . LYS   D 2 458 ? 228.607 179.393 235.797 1.00 62.07  ? 470 LYS   A CG    1 
ATOM   3873 C CD    . LYS   D 2 458 ? 229.026 179.400 234.342 1.00 63.01  ? 470 LYS   A CD    1 
ATOM   3874 C CE    . LYS   D 2 458 ? 230.004 178.280 234.053 1.00 68.81  ? 470 LYS   A CE    1 
ATOM   3875 N NZ    . LYS   D 2 458 ? 229.894 177.186 235.054 1.00 69.07  ? 470 LYS   A NZ    1 
ATOM   3876 N N     . ALA   D 2 459 ? 228.914 183.464 238.418 1.00 59.71  ? 471 ALA   A N     1 
ATOM   3877 C CA    . ALA   D 2 459 ? 228.531 184.840 238.730 1.00 58.26  ? 471 ALA   A CA    1 
ATOM   3878 C C     . ALA   D 2 459 ? 227.131 185.151 238.198 1.00 59.24  ? 471 ALA   A C     1 
ATOM   3879 O O     . ALA   D 2 459 ? 226.931 186.034 237.364 1.00 64.25  ? 471 ALA   A O     1 
ATOM   3880 C CB    . ALA   D 2 459 ? 229.563 185.834 238.188 1.00 56.87  ? 471 ALA   A CB    1 
ATOM   3881 N N     . THR   D 2 460 ? 226.155 184.400 238.705 1.00 56.40  ? 472 THR   A N     1 
ATOM   3882 C CA    . THR   D 2 460 ? 224.769 184.534 238.276 1.00 57.49  ? 472 THR   A CA    1 
ATOM   3883 C C     . THR   D 2 460 ? 223.953 185.443 239.187 1.00 57.37  ? 472 THR   A C     1 
ATOM   3884 O O     . THR   D 2 460 ? 223.289 186.364 238.705 1.00 62.66  ? 472 THR   A O     1 
ATOM   3885 C CB    . THR   D 2 460 ? 224.106 183.155 238.193 1.00 61.91  ? 472 THR   A CB    1 
ATOM   3886 O OG1   . THR   D 2 460 ? 224.264 182.472 239.441 1.00 63.15  ? 472 THR   A OG1   1 
ATOM   3887 C CG2   . THR   D 2 460 ? 224.741 182.330 237.091 1.00 63.66  ? 472 THR   A CG2   1 
ATOM   3888 N N     . SER   D 2 461 ? 223.986 185.207 240.495 1.00 54.00  ? 473 SER   A N     1 
ATOM   3889 C CA    . SER   D 2 461 ? 223.174 185.985 241.425 1.00 55.54  ? 473 SER   A CA    1 
ATOM   3890 C C     . SER   D 2 461 ? 224.053 186.946 242.210 1.00 51.96  ? 473 SER   A C     1 
ATOM   3891 O O     . SER   D 2 461 ? 224.806 186.506 243.092 1.00 54.57  ? 473 SER   A O     1 
ATOM   3892 C CB    . SER   D 2 461 ? 222.412 185.061 242.375 1.00 52.51  ? 473 SER   A CB    1 
ATOM   3893 O OG    . SER   D 2 461 ? 223.300 184.255 243.124 1.00 55.31  ? 473 SER   A OG    1 
ATOM   3894 N N     . PRO   D 2 462 ? 224.003 188.245 241.936 1.00 54.64  ? 474 PRO   A N     1 
ATOM   3895 C CA    . PRO   D 2 462 ? 224.827 189.194 242.685 1.00 55.39  ? 474 PRO   A CA    1 
ATOM   3896 C C     . PRO   D 2 462 ? 224.176 189.595 244.001 1.00 55.37  ? 474 PRO   A C     1 
ATOM   3897 O O     . PRO   D 2 462 ? 222.958 189.545 244.172 1.00 59.71  ? 474 PRO   A O     1 
ATOM   3898 C CB    . PRO   D 2 462 ? 224.934 190.401 241.741 1.00 53.42  ? 474 PRO   A CB    1 
ATOM   3899 C CG    . PRO   D 2 462 ? 224.282 189.979 240.449 1.00 52.47  ? 474 PRO   A CG    1 
ATOM   3900 C CD    . PRO   D 2 462 ? 223.326 188.893 240.805 1.00 57.97  ? 474 PRO   A CD    1 
ATOM   3901 N N     . ILE   D 2 463 ? 225.027 190.000 244.939 1.00 51.19  ? 475 ILE   A N     1 
ATOM   3902 C CA    . ILE   D 2 463 ? 224.598 190.532 246.227 1.00 51.96  ? 475 ILE   A CA    1 
ATOM   3903 C C     . ILE   D 2 463 ? 225.072 191.975 246.309 1.00 52.89  ? 475 ILE   A C     1 
ATOM   3904 O O     . ILE   D 2 463 ? 226.276 192.243 246.218 1.00 54.20  ? 475 ILE   A O     1 
ATOM   3905 C CB    . ILE   D 2 463 ? 225.145 189.708 247.403 1.00 52.30  ? 475 ILE   A CB    1 
ATOM   3906 C CG1   . ILE   D 2 463 ? 224.426 188.364 247.499 1.00 52.29  ? 475 ILE   A CG1   1 
ATOM   3907 C CG2   . ILE   D 2 463 ? 224.999 190.473 248.704 1.00 50.73  ? 475 ILE   A CG2   1 
ATOM   3908 C CD1   . ILE   D 2 463 ? 225.278 187.191 247.099 1.00 55.23  ? 475 ILE   A CD1   1 
ATOM   3909 N N     . VAL   D 2 464 ? 224.133 192.898 246.482 1.00 53.33  ? 476 VAL   A N     1 
ATOM   3910 C CA    . VAL   D 2 464 ? 224.450 194.320 246.575 1.00 53.95  ? 476 VAL   A CA    1 
ATOM   3911 C C     . VAL   D 2 464 ? 224.613 194.702 248.041 1.00 55.40  ? 476 VAL   A C     1 
ATOM   3912 O O     . VAL   D 2 464 ? 223.733 194.401 248.860 1.00 53.61  ? 476 VAL   A O     1 
ATOM   3913 C CB    . VAL   D 2 464 ? 223.372 195.173 245.891 1.00 54.60  ? 476 VAL   A CB    1 
ATOM   3914 C CG1   . VAL   D 2 464 ? 223.613 196.646 246.157 1.00 58.58  ? 476 VAL   A CG1   1 
ATOM   3915 C CG2   . VAL   D 2 464 ? 223.352 194.896 244.401 1.00 50.49  ? 476 VAL   A CG2   1 
ATOM   3916 N N     . PRO   D 2 465 ? 225.713 195.342 248.423 1.00 58.56  ? 477 PRO   A N     1 
ATOM   3917 C CA    . PRO   D 2 465 ? 225.883 195.746 249.819 1.00 56.92  ? 477 PRO   A CA    1 
ATOM   3918 C C     . PRO   D 2 465 ? 225.129 197.024 250.135 1.00 62.89  ? 477 PRO   A C     1 
ATOM   3919 O O     . PRO   D 2 465 ? 225.001 197.929 249.308 1.00 67.45  ? 477 PRO   A O     1 
ATOM   3920 C CB    . PRO   D 2 465 ? 227.397 195.961 249.949 1.00 56.86  ? 477 PRO   A CB    1 
ATOM   3921 C CG    . PRO   D 2 465 ? 227.978 195.734 248.579 1.00 53.99  ? 477 PRO   A CG    1 
ATOM   3922 C CD    . PRO   D 2 465 ? 226.857 195.749 247.599 1.00 55.66  ? 477 PRO   A CD    1 
ATOM   3923 N N     . SER   D 2 466 ? 224.628 197.089 251.361 1.00 65.22  ? 478 SER   A N     1 
ATOM   3924 C CA    . SER   D 2 466 ? 223.945 198.272 251.873 1.00 72.48  ? 478 SER   A CA    1 
ATOM   3925 C C     . SER   D 2 466 ? 224.803 198.832 253.000 1.00 82.38  ? 478 SER   A C     1 
ATOM   3926 O O     . SER   D 2 466 ? 224.752 198.342 254.131 1.00 94.80  ? 478 SER   A O     1 
ATOM   3927 C CB    . SER   D 2 466 ? 222.538 197.934 252.351 1.00 75.94  ? 478 SER   A CB    1 
ATOM   3928 O OG    . SER   D 2 466 ? 222.579 197.007 253.420 1.00 82.58  ? 478 SER   A OG    1 
ATOM   3929 N N     . PHE   D 2 467 ? 225.592 199.857 252.691 1.00 78.22  ? 479 PHE   A N     1 
ATOM   3930 C CA    . PHE   D 2 467 ? 226.491 200.460 253.661 1.00 86.47  ? 479 PHE   A CA    1 
ATOM   3931 C C     . PHE   D 2 467 ? 225.810 201.529 254.501 1.00 104.88 ? 479 PHE   A C     1 
ATOM   3932 O O     . PHE   D 2 467 ? 226.492 202.392 255.063 1.00 106.48 ? 479 PHE   A O     1 
ATOM   3933 C CB    . PHE   D 2 467 ? 227.714 201.042 252.954 1.00 74.91  ? 479 PHE   A CB    1 
ATOM   3934 C CG    . PHE   D 2 467 ? 228.544 200.013 252.256 1.00 64.96  ? 479 PHE   A CG    1 
ATOM   3935 C CD1   . PHE   D 2 467 ? 228.866 198.828 252.887 1.00 61.44  ? 479 PHE   A CD1   1 
ATOM   3936 C CD2   . PHE   D 2 467 ? 228.999 200.226 250.968 1.00 61.47  ? 479 PHE   A CD2   1 
ATOM   3937 C CE1   . PHE   D 2 467 ? 229.623 197.875 252.247 1.00 62.46  ? 479 PHE   A CE1   1 
ATOM   3938 C CE2   . PHE   D 2 467 ? 229.759 199.275 250.323 1.00 56.59  ? 479 PHE   A CE2   1 
ATOM   3939 C CZ    . PHE   D 2 467 ? 230.071 198.099 250.964 1.00 60.31  ? 479 PHE   A CZ    1 
ATOM   3940 N N     . ASP   D 2 468 ? 224.485 201.486 254.606 1.00 120.28 ? 480 ASP   A N     1 
ATOM   3941 C CA    . ASP   D 2 468 ? 223.728 202.536 255.286 1.00 134.78 ? 480 ASP   A CA    1 
ATOM   3942 C C     . ASP   D 2 468 ? 223.494 202.188 256.758 1.00 139.06 ? 480 ASP   A C     1 
ATOM   3943 O O     . ASP   D 2 468 ? 222.367 202.129 257.245 1.00 145.15 ? 480 ASP   A O     1 
ATOM   3944 C CB    . ASP   D 2 468 ? 222.411 202.785 254.559 1.00 141.79 ? 480 ASP   A CB    1 
ATOM   3945 C CG    . ASP   D 2 468 ? 222.613 203.358 253.171 1.00 145.44 ? 480 ASP   A CG    1 
ATOM   3946 O OD1   . ASP   D 2 468 ? 223.782 203.528 252.763 1.00 138.82 ? 480 ASP   A OD1   1 
ATOM   3947 O OD2   . ASP   D 2 468 ? 221.606 203.641 252.489 1.00 156.84 ? 480 ASP   A OD2   1 
ATOM   3948 N N     . MET   D 2 469 ? 224.592 201.953 257.468 1.00 131.38 ? 481 MET   A N     1 
ATOM   3949 C CA    . MET   D 2 469 ? 224.571 201.940 258.927 1.00 139.35 ? 481 MET   A CA    1 
ATOM   3950 C C     . MET   D 2 469 ? 225.655 202.914 259.388 1.00 141.42 ? 481 MET   A C     1 
ATOM   3951 O O     . MET   D 2 469 ? 226.201 203.690 258.594 1.00 133.73 ? 481 MET   A O     1 
ATOM   3952 C CB    . MET   D 2 469 ? 224.714 200.524 259.518 1.00 142.82 ? 481 MET   A CB    1 
ATOM   3953 C CG    . MET   D 2 469 ? 226.128 199.933 259.672 1.00 147.86 ? 481 MET   A CG    1 
ATOM   3954 S SD    . MET   D 2 469 ? 227.318 200.239 258.360 1.00 149.03 ? 481 MET   A SD    1 
ATOM   3955 C CE    . MET   D 2 469 ? 226.467 199.456 257.000 1.00 121.91 ? 481 MET   A CE    1 
ATOM   3956 N N     . SER   D 2 470 ? 225.946 202.900 260.691 1.00 148.43 ? 482 SER   A N     1 
ATOM   3957 C CA    . SER   D 2 470 ? 226.977 203.766 261.249 1.00 147.05 ? 482 SER   A CA    1 
ATOM   3958 C C     . SER   D 2 470 ? 228.256 203.657 260.429 1.00 136.62 ? 482 SER   A C     1 
ATOM   3959 O O     . SER   D 2 470 ? 228.632 202.578 259.969 1.00 130.43 ? 482 SER   A O     1 
ATOM   3960 C CB    . SER   D 2 470 ? 227.245 203.398 262.711 1.00 151.86 ? 482 SER   A CB    1 
ATOM   3961 O OG    . SER   D 2 470 ? 228.257 204.216 263.271 1.00 153.59 ? 482 SER   A OG    1 
ATOM   3962 N N     . ASN   D 2 471 ? 228.921 204.791 260.241 1.00 131.67 ? 483 ASN   A N     1 
ATOM   3963 C CA    . ASN   D 2 471 ? 229.967 204.919 259.237 1.00 127.01 ? 483 ASN   A CA    1 
ATOM   3964 C C     . ASN   D 2 471 ? 231.303 204.436 259.788 1.00 121.47 ? 483 ASN   A C     1 
ATOM   3965 O O     . ASN   D 2 471 ? 231.753 204.904 260.839 1.00 125.15 ? 483 ASN   A O     1 
ATOM   3966 C CB    . ASN   D 2 471 ? 230.077 206.371 258.774 1.00 127.63 ? 483 ASN   A CB    1 
ATOM   3967 C CG    . ASN   D 2 471 ? 228.737 206.955 258.380 1.00 132.31 ? 483 ASN   A CG    1 
ATOM   3968 O OD1   . ASN   D 2 471 ? 227.696 206.327 258.565 1.00 132.69 ? 483 ASN   A OD1   1 
ATOM   3969 N ND2   . ASN   D 2 471 ? 228.756 208.165 257.833 1.00 136.16 ? 483 ASN   A ND2   1 
ATOM   3970 N N     . GLU   D 2 472 ? 231.927 203.496 259.083 1.00 112.58 ? 484 GLU   A N     1 
ATOM   3971 C CA    . GLU   D 2 472 ? 233.323 203.176 259.328 1.00 104.34 ? 484 GLU   A CA    1 
ATOM   3972 C C     . GLU   D 2 472 ? 234.200 204.038 258.428 1.00 91.73  ? 484 GLU   A C     1 
ATOM   3973 O O     . GLU   D 2 472 ? 233.719 204.779 257.569 1.00 84.81  ? 484 GLU   A O     1 
ATOM   3974 C CB    . GLU   D 2 472 ? 233.637 201.692 259.080 1.00 106.66 ? 484 GLU   A CB    1 
ATOM   3975 C CG    . GLU   D 2 472 ? 233.018 200.634 260.017 1.00 120.10 ? 484 GLU   A CG    1 
ATOM   3976 C CD    . GLU   D 2 472 ? 233.328 199.196 259.649 1.00 131.40 ? 484 GLU   A CD    1 
ATOM   3977 O OE1   . GLU   D 2 472 ? 233.875 198.969 258.551 1.00 126.61 ? 484 GLU   A OE1   1 
ATOM   3978 O OE2   . GLU   D 2 472 ? 233.029 198.294 260.460 1.00 136.53 ? 484 GLU   A OE2   1 
ATOM   3979 N N     . GLY   D 2 473 ? 235.508 203.939 258.637 1.00 86.06  ? 485 GLY   A N     1 
ATOM   3980 C CA    . GLY   D 2 473 ? 236.436 204.604 257.752 1.00 73.07  ? 485 GLY   A CA    1 
ATOM   3981 C C     . GLY   D 2 473 ? 236.421 203.997 256.364 1.00 64.13  ? 485 GLY   A C     1 
ATOM   3982 O O     . GLY   D 2 473 ? 236.000 202.861 256.151 1.00 64.35  ? 485 GLY   A O     1 
ATOM   3983 N N     . SER   D 2 474 ? 236.890 204.778 255.395 1.00 58.43  ? 486 SER   A N     1 
ATOM   3984 C CA    . SER   D 2 474 ? 236.882 204.346 254.008 1.00 55.53  ? 486 SER   A CA    1 
ATOM   3985 C C     . SER   D 2 474 ? 238.256 204.290 253.363 1.00 57.37  ? 486 SER   A C     1 
ATOM   3986 O O     . SER   D 2 474 ? 238.422 203.556 252.383 1.00 60.01  ? 486 SER   A O     1 
ATOM   3987 C CB    . SER   D 2 474 ? 235.984 205.264 253.166 1.00 53.65  ? 486 SER   A CB    1 
ATOM   3988 O OG    . SER   D 2 474 ? 236.023 204.894 251.802 1.00 61.61  ? 486 SER   A OG    1 
ATOM   3989 N N     . TYR   D 2 475 ? 239.236 205.024 253.872 1.00 55.61  ? 487 TYR   A N     1 
ATOM   3990 C CA    . TYR   D 2 475 ? 240.551 205.110 253.252 1.00 52.60  ? 487 TYR   A CA    1 
ATOM   3991 C C     . TYR   D 2 475 ? 241.543 204.286 254.063 1.00 52.61  ? 487 TYR   A C     1 
ATOM   3992 O O     . TYR   D 2 475 ? 241.658 204.468 255.279 1.00 54.69  ? 487 TYR   A O     1 
ATOM   3993 C CB    . TYR   D 2 475 ? 241.007 206.564 253.152 1.00 55.00  ? 487 TYR   A CB    1 
ATOM   3994 C CG    . TYR   D 2 475 ? 239.899 207.522 252.787 1.00 55.51  ? 487 TYR   A CG    1 
ATOM   3995 C CD1   . TYR   D 2 475 ? 239.443 207.621 251.483 1.00 49.52  ? 487 TYR   A CD1   1 
ATOM   3996 C CD2   . TYR   D 2 475 ? 239.304 208.322 253.749 1.00 56.57  ? 487 TYR   A CD2   1 
ATOM   3997 C CE1   . TYR   D 2 475 ? 238.428 208.486 251.147 1.00 49.52  ? 487 TYR   A CE1   1 
ATOM   3998 C CE2   . TYR   D 2 475 ? 238.290 209.194 253.421 1.00 52.42  ? 487 TYR   A CE2   1 
ATOM   3999 C CZ    . TYR   D 2 475 ? 237.857 209.272 252.120 1.00 54.66  ? 487 TYR   A CZ    1 
ATOM   4000 O OH    . TYR   D 2 475 ? 236.846 210.141 251.793 1.00 62.03  ? 487 TYR   A OH    1 
ATOM   4001 N N     . PHE   D 2 476 ? 242.249 203.380 253.385 1.00 52.31  ? 488 PHE   A N     1 
ATOM   4002 C CA    . PHE   D 2 476 ? 243.250 202.558 254.057 1.00 49.60  ? 488 PHE   A CA    1 
ATOM   4003 C C     . PHE   D 2 476 ? 244.370 203.418 254.629 1.00 50.67  ? 488 PHE   A C     1 
ATOM   4004 O O     . PHE   D 2 476 ? 244.793 203.230 255.775 1.00 50.38  ? 488 PHE   A O     1 
ATOM   4005 C CB    . PHE   D 2 476 ? 243.805 201.522 253.078 1.00 45.12  ? 488 PHE   A CB    1 
ATOM   4006 C CG    . PHE   D 2 476 ? 244.759 200.542 253.697 1.00 47.87  ? 488 PHE   A CG    1 
ATOM   4007 C CD1   . PHE   D 2 476 ? 244.468 199.936 254.903 1.00 50.03  ? 488 PHE   A CD1   1 
ATOM   4008 C CD2   . PHE   D 2 476 ? 245.944 200.215 253.060 1.00 49.03  ? 488 PHE   A CD2   1 
ATOM   4009 C CE1   . PHE   D 2 476 ? 245.343 199.030 255.467 1.00 47.28  ? 488 PHE   A CE1   1 
ATOM   4010 C CE2   . PHE   D 2 476 ? 246.822 199.312 253.623 1.00 46.85  ? 488 PHE   A CE2   1 
ATOM   4011 C CZ    . PHE   D 2 476 ? 246.520 198.720 254.828 1.00 44.29  ? 488 PHE   A CZ    1 
ATOM   4012 N N     . PHE   D 2 477 ? 244.860 204.370 253.844 1.00 48.31  ? 489 PHE   A N     1 
ATOM   4013 C CA    . PHE   D 2 477 ? 245.940 205.261 254.263 1.00 48.90  ? 489 PHE   A CA    1 
ATOM   4014 C C     . PHE   D 2 477 ? 245.377 206.598 254.741 1.00 53.56  ? 489 PHE   A C     1 
ATOM   4015 O O     . PHE   D 2 477 ? 245.608 207.646 254.144 1.00 59.71  ? 489 PHE   A O     1 
ATOM   4016 C CB    . PHE   D 2 477 ? 246.928 205.461 253.118 1.00 47.56  ? 489 PHE   A CB    1 
ATOM   4017 C CG    . PHE   D 2 477 ? 247.673 204.220 252.730 1.00 49.32  ? 489 PHE   A CG    1 
ATOM   4018 C CD1   . PHE   D 2 477 ? 248.664 203.706 253.544 1.00 51.19  ? 489 PHE   A CD1   1 
ATOM   4019 C CD2   . PHE   D 2 477 ? 247.388 203.572 251.544 1.00 52.73  ? 489 PHE   A CD2   1 
ATOM   4020 C CE1   . PHE   D 2 477 ? 249.352 202.567 253.183 1.00 50.27  ? 489 PHE   A CE1   1 
ATOM   4021 C CE2   . PHE   D 2 477 ? 248.072 202.433 251.179 1.00 52.12  ? 489 PHE   A CE2   1 
ATOM   4022 C CZ    . PHE   D 2 477 ? 249.055 201.931 252.000 1.00 49.05  ? 489 PHE   A CZ    1 
ATOM   4023 N N     . GLY   D 2 478 ? 244.627 206.556 255.836 1.00 45.67  ? 490 GLY   A N     1 
ATOM   4024 C CA    . GLY   D 2 478 ? 243.981 207.752 256.346 1.00 43.63  ? 490 GLY   A CA    1 
ATOM   4025 C C     . GLY   D 2 478 ? 244.000 207.889 257.854 1.00 45.63  ? 490 GLY   A C     1 
ATOM   4026 O O     . GLY   D 2 478 ? 243.994 209.000 258.385 1.00 35.24  ? 490 GLY   A O     1 
HETATM 4027 C C1    . A1IJK E 3 .   ? 264.775 204.154 240.436 1.00 132.88 ? 101 A1IJK C C1    1 
HETATM 4028 C C2    . A1IJK E 3 .   ? 263.546 203.768 241.217 1.00 139.30 ? 101 A1IJK C C2    1 
HETATM 4029 C C3    . A1IJK E 3 .   ? 263.830 203.608 242.693 1.00 140.15 ? 101 A1IJK C C3    1 
HETATM 4030 C C6    . A1IJK E 3 .   ? 265.286 202.476 244.202 1.00 137.33 ? 101 A1IJK C C6    1 
HETATM 4031 C C7    . A1IJK E 3 .   ? 264.248 201.516 244.743 1.00 138.35 ? 101 A1IJK C C7    1 
HETATM 4032 O O4    . A1IJK E 3 .   ? 264.988 202.798 242.849 1.00 139.26 ? 101 A1IJK C O4    1 
HETATM 4033 O O5    . A1IJK E 3 .   ? 263.044 202.535 240.703 1.00 137.65 ? 101 A1IJK C O5    1 
HETATM 4034 C C8    . A1IJK E 3 .   ? 264.134 200.236 243.938 1.00 136.99 ? 101 A1IJK C C8    1 
HETATM 4035 C C10   . A1IJK E 3 .   ? 265.986 199.463 242.558 1.00 132.08 ? 101 A1IJK C C10   1 
HETATM 4036 N N9    . A1IJK E 3 .   ? 265.435 199.608 243.762 1.00 133.31 ? 101 A1IJK C N9    1 
HETATM 4037 C C33   . A1IJK E 3 .   ? 270.499 201.061 246.797 1.00 122.86 ? 101 A1IJK C C33   1 
HETATM 4038 C C34   . A1IJK E 3 .   ? 270.180 200.163 245.823 1.00 120.10 ? 101 A1IJK C C34   1 
HETATM 4039 C C11   . A1IJK E 3 .   ? 267.421 199.026 242.521 1.00 124.31 ? 101 A1IJK C C11   1 
HETATM 4040 C C12   . A1IJK E 3 .   ? 268.127 198.991 241.328 1.00 125.16 ? 101 A1IJK C C12   1 
HETATM 4041 C C13   . A1IJK E 3 .   ? 269.446 198.587 241.314 1.00 128.48 ? 101 A1IJK C C13   1 
HETATM 4042 C C14   . A1IJK E 3 .   ? 270.099 198.202 242.480 1.00 128.35 ? 101 A1IJK C C14   1 
HETATM 4043 C C15   . A1IJK E 3 .   ? 269.387 198.245 243.697 1.00 122.38 ? 101 A1IJK C C15   1 
HETATM 4044 C C16   . A1IJK E 3 .   ? 268.056 198.646 243.696 1.00 121.10 ? 101 A1IJK C C16   1 
HETATM 4045 C C17   . A1IJK E 3 .   ? 271.545 197.777 242.357 1.00 131.10 ? 101 A1IJK C C17   1 
HETATM 4046 C C20   . A1IJK E 3 .   ? 269.989 197.836 245.000 1.00 120.41 ? 101 A1IJK C C20   1 
HETATM 4047 C C21   . A1IJK E 3 .   ? 270.173 196.431 245.302 1.00 119.53 ? 101 A1IJK C C21   1 
HETATM 4048 C C22   . A1IJK E 3 .   ? 270.777 196.056 246.527 1.00 121.22 ? 101 A1IJK C C22   1 
HETATM 4049 C C24   . A1IJK E 3 .   ? 270.990 198.341 247.203 1.00 126.40 ? 101 A1IJK C C24   1 
HETATM 4050 C C25   . A1IJK E 3 .   ? 270.389 198.800 246.011 1.00 121.69 ? 101 A1IJK C C25   1 
HETATM 4051 C C27   . A1IJK E 3 .   ? 270.906 194.714 246.842 1.00 120.13 ? 101 A1IJK C C27   1 
HETATM 4052 C C28   . A1IJK E 3 .   ? 270.395 193.700 245.946 1.00 123.03 ? 101 A1IJK C C28   1 
HETATM 4053 C C29   . A1IJK E 3 .   ? 269.840 194.123 244.700 1.00 120.85 ? 101 A1IJK C C29   1 
HETATM 4054 C C30   . A1IJK E 3 .   ? 269.747 195.466 244.394 1.00 119.73 ? 101 A1IJK C C30   1 
HETATM 4055 C C31   . A1IJK E 3 .   ? 271.339 199.268 248.181 1.00 126.77 ? 101 A1IJK C C31   1 
HETATM 4056 C C32   . A1IJK E 3 .   ? 271.065 200.657 247.991 1.00 125.31 ? 101 A1IJK C C32   1 
HETATM 4057 O O18   . A1IJK E 3 .   ? 272.173 197.484 243.389 1.00 130.13 ? 101 A1IJK C O18   1 
HETATM 4058 O O19   . A1IJK E 3 .   ? 272.034 197.747 241.213 1.00 133.07 ? 101 A1IJK C O19   1 
HETATM 4059 O O23   . A1IJK E 3 .   ? 271.217 197.001 247.426 1.00 127.54 ? 101 A1IJK C O23   1 
HETATM 4060 O O26   . A1IJK E 3 .   ? 265.366 199.692 241.520 1.00 136.19 ? 101 A1IJK C O26   1 
HETATM 4061 O O35   . A1IJK E 3 .   ? 270.445 192.503 246.244 1.00 127.83 ? 101 A1IJK C O35   1 
HETATM 4062 O O36   . A1IJK E 3 .   ? 271.335 201.481 248.871 1.00 125.38 ? 101 A1IJK C O36   1 
# 
