data_9GAP
# 
_entry.id   9GAP 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GAP         pdb_00009gap 10.2210/pdb9gap/pdb 
WWPDB D_1292140511 ?            ?                   
EMDB  EMD-51185    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-15 
2 'Structure model' 1 1 2025-02-12 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 2 'Structure model' em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation.year'           
3 2 'Structure model' '_em_admin.last_update'    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GAP 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-29 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'map of the single stranded helical assembly with 12mer RNA'                                     EMD-51184 'other EM volume' 
EMDB 'map of the double stranded parallel helical assembly with 14mer RNA'                            EMD-51186 'other EM volume' 
EMDB 'focused map on Strand 2 of the double stranded antiparallel helical assembly with 18mer RNA'    EMD-51187 'other EM volume' 
EMDB 'focused map on Strand 1 of the double stranded antiparallel helical assembly with 18mer RNA'    EMD-51189 'other EM volume' 
EMDB 'global map of the double stranded antiparallel helical assembly with 18mer RNA'                 EMD-51188 'other EM volume' 
EMDB 'CryoEM structure of influenza A RNP-like particle double-stranded assembled with a 12-mer RNA.' EMD-51185 
'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 thibaut.crepin@ibs.fr           Thibaut Crepin           ? 'principal investigator/group leader' 0000-0003-2663-1794 
3 allison.ballandras-colas@ibs.fr Allison Ballandras-Colas ? 'principal investigator/group leader' 0000-0003-4735-4984 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Chenavier, F.'        1 0000-0002-9486-3944 
'Ruigrok, R.W.H.'      2 0000-0002-8094-6642 
'Schoehn, G.'          3 0000-0002-1459-3201 
'Ballandras-Colas, A.' 4 0000-0003-4735-4984 
'Crepin, T.'           5 0000-0003-2663-1794 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nucleic Acids Res.' 
_citation.journal_id_ASTM           NARHAD 
_citation.journal_id_CSD            0389 
_citation.journal_id_ISSN           1362-4962 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            53 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Influenza a virus antiparallel helical nucleocapsid-like pseudo-atomic structure.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1093/nar/gkae1211 
_citation.pdbx_database_id_PubMed   39673795 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chenavier, F.'        1 0000-0002-9486-3944 
primary 'Zarkadas, E.'         2 0000-0002-9276-9831 
primary 'Freslon, L.L.'        3 ?                   
primary 'Stelfox, A.J.'        4 0000-0003-4553-6565 
primary 'Schoehn, G.'          5 0000-0002-1459-3201 
primary 'Ruigrok, R.W.H.'      6 0000-0002-8094-6642 
primary 'Ballandras-Colas, A.' 7 0000-0003-4735-4984 
primary 'Crepin, T.'           8 0000-0003-2663-1794 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     syn 
;RNA (5'-P(UC)6-FAM3')
;
3623.128  2 ? ? ? ? 
2 polymer     man Nucleoprotein                                                                                                  
56150.395 2 ? ? ? ? 
3 non-polymer syn '2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2R)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid' 
493.505   1 ? ? ? ? 
# 
_entity_name_com.entity_id   2 
_entity_name_com.name        'Nucleocapsid protein,Protein N' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 polyribonucleotide no no UCUCUCUCUCUC UCUCUCUCUCUC C,D ? 
2 'polypeptide(L)'   no no 
;HMTDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKT
GGPIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTL
PRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAE
FEDLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMA
CHSAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTF
SVQRNLPFDRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDN
AEEYDNLEHHHHHH
;
;HMTDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKT
GGPIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTL
PRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAE
FEDLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMA
CHSAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTF
SVQRNLPFDRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDN
AEEYDNLEHHHHHH
;
A,B ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        
'2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2R)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid' 
_pdbx_entity_nonpoly.comp_id     A1IJK 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   U   n 
1 2   C   n 
1 3   U   n 
1 4   C   n 
1 5   U   n 
1 6   C   n 
1 7   U   n 
1 8   C   n 
1 9   U   n 
1 10  C   n 
1 11  U   n 
1 12  C   n 
2 1   HIS n 
2 2   MET n 
2 3   THR n 
2 4   ASP n 
2 5   GLY n 
2 6   GLU n 
2 7   ARG n 
2 8   GLN n 
2 9   ASN n 
2 10  ALA n 
2 11  THR n 
2 12  GLU n 
2 13  ILE n 
2 14  ARG n 
2 15  ALA n 
2 16  SER n 
2 17  VAL n 
2 18  GLY n 
2 19  LYS n 
2 20  MET n 
2 21  ILE n 
2 22  ASP n 
2 23  GLY n 
2 24  ILE n 
2 25  GLY n 
2 26  ARG n 
2 27  PHE n 
2 28  TYR n 
2 29  ILE n 
2 30  GLN n 
2 31  MET n 
2 32  CYS n 
2 33  THR n 
2 34  GLU n 
2 35  LEU n 
2 36  LYS n 
2 37  LEU n 
2 38  SER n 
2 39  ASP n 
2 40  TYR n 
2 41  GLU n 
2 42  GLY n 
2 43  ARG n 
2 44  LEU n 
2 45  ILE n 
2 46  GLN n 
2 47  ASN n 
2 48  SER n 
2 49  LEU n 
2 50  THR n 
2 51  ILE n 
2 52  GLU n 
2 53  ARG n 
2 54  MET n 
2 55  VAL n 
2 56  LEU n 
2 57  SER n 
2 58  ALA n 
2 59  PHE n 
2 60  ASP n 
2 61  GLU n 
2 62  ARG n 
2 63  ARG n 
2 64  ASN n 
2 65  LYS n 
2 66  TYR n 
2 67  LEU n 
2 68  GLU n 
2 69  GLU n 
2 70  HIS n 
2 71  PRO n 
2 72  SER n 
2 73  ALA n 
2 74  GLY n 
2 75  LYS n 
2 76  ASP n 
2 77  PRO n 
2 78  LYS n 
2 79  LYS n 
2 80  THR n 
2 81  GLY n 
2 82  GLY n 
2 83  PRO n 
2 84  ILE n 
2 85  TYR n 
2 86  ARG n 
2 87  ARG n 
2 88  VAL n 
2 89  ASP n 
2 90  GLY n 
2 91  LYS n 
2 92  TRP n 
2 93  ARG n 
2 94  ARG n 
2 95  GLU n 
2 96  LEU n 
2 97  ILE n 
2 98  LEU n 
2 99  TYR n 
2 100 ASP n 
2 101 LYS n 
2 102 GLU n 
2 103 GLU n 
2 104 ILE n 
2 105 ARG n 
2 106 ARG n 
2 107 ILE n 
2 108 TRP n 
2 109 ARG n 
2 110 GLN n 
2 111 ALA n 
2 112 ASN n 
2 113 ASN n 
2 114 GLY n 
2 115 ASP n 
2 116 ASP n 
2 117 ALA n 
2 118 THR n 
2 119 ALA n 
2 120 GLY n 
2 121 LEU n 
2 122 THR n 
2 123 HIS n 
2 124 MET n 
2 125 MET n 
2 126 ILE n 
2 127 TRP n 
2 128 HIS n 
2 129 SER n 
2 130 ASN n 
2 131 LEU n 
2 132 ASN n 
2 133 ASP n 
2 134 ALA n 
2 135 THR n 
2 136 TYR n 
2 137 GLN n 
2 138 ARG n 
2 139 THR n 
2 140 ARG n 
2 141 ALA n 
2 142 LEU n 
2 143 VAL n 
2 144 ARG n 
2 145 THR n 
2 146 GLY n 
2 147 MET n 
2 148 ASP n 
2 149 PRO n 
2 150 ARG n 
2 151 MET n 
2 152 CYS n 
2 153 SER n 
2 154 LEU n 
2 155 MET n 
2 156 GLN n 
2 157 GLY n 
2 158 SER n 
2 159 THR n 
2 160 LEU n 
2 161 PRO n 
2 162 ARG n 
2 163 ARG n 
2 164 SER n 
2 165 GLY n 
2 166 ALA n 
2 167 ALA n 
2 168 GLY n 
2 169 ALA n 
2 170 ALA n 
2 171 VAL n 
2 172 LYS n 
2 173 GLY n 
2 174 VAL n 
2 175 GLY n 
2 176 THR n 
2 177 MET n 
2 178 VAL n 
2 179 MET n 
2 180 GLU n 
2 181 LEU n 
2 182 ILE n 
2 183 ARG n 
2 184 MET n 
2 185 ILE n 
2 186 LYS n 
2 187 ARG n 
2 188 GLY n 
2 189 ILE n 
2 190 ASN n 
2 191 ASP n 
2 192 ARG n 
2 193 ASN n 
2 194 PHE n 
2 195 TRP n 
2 196 ARG n 
2 197 GLY n 
2 198 GLU n 
2 199 ASN n 
2 200 GLY n 
2 201 ARG n 
2 202 ARG n 
2 203 THR n 
2 204 ARG n 
2 205 ILE n 
2 206 ALA n 
2 207 TYR n 
2 208 GLU n 
2 209 ARG n 
2 210 MET n 
2 211 CYS n 
2 212 ASN n 
2 213 ILE n 
2 214 LEU n 
2 215 LYS n 
2 216 GLY n 
2 217 LYS n 
2 218 PHE n 
2 219 GLN n 
2 220 THR n 
2 221 ALA n 
2 222 ALA n 
2 223 GLN n 
2 224 ARG n 
2 225 THR n 
2 226 MET n 
2 227 VAL n 
2 228 ASP n 
2 229 GLN n 
2 230 VAL n 
2 231 ARG n 
2 232 GLU n 
2 233 SER n 
2 234 ARG n 
2 235 ASN n 
2 236 PRO n 
2 237 GLY n 
2 238 ASN n 
2 239 ALA n 
2 240 GLU n 
2 241 PHE n 
2 242 GLU n 
2 243 ASP n 
2 244 LEU n 
2 245 ILE n 
2 246 PHE n 
2 247 LEU n 
2 248 ALA n 
2 249 ARG n 
2 250 SER n 
2 251 ALA n 
2 252 LEU n 
2 253 ILE n 
2 254 LEU n 
2 255 ARG n 
2 256 GLY n 
2 257 SER n 
2 258 VAL n 
2 259 ALA n 
2 260 HIS n 
2 261 LYS n 
2 262 SER n 
2 263 CYS n 
2 264 LEU n 
2 265 PRO n 
2 266 ALA n 
2 267 CYS n 
2 268 VAL n 
2 269 TYR n 
2 270 GLY n 
2 271 SER n 
2 272 ALA n 
2 273 VAL n 
2 274 ALA n 
2 275 SER n 
2 276 GLY n 
2 277 TYR n 
2 278 ASP n 
2 279 PHE n 
2 280 GLU n 
2 281 ARG n 
2 282 GLU n 
2 283 GLY n 
2 284 TYR n 
2 285 SER n 
2 286 LEU n 
2 287 VAL n 
2 288 GLY n 
2 289 ILE n 
2 290 ASP n 
2 291 PRO n 
2 292 PHE n 
2 293 ARG n 
2 294 LEU n 
2 295 LEU n 
2 296 GLN n 
2 297 ASN n 
2 298 SER n 
2 299 GLN n 
2 300 VAL n 
2 301 TYR n 
2 302 SER n 
2 303 LEU n 
2 304 ILE n 
2 305 ARG n 
2 306 PRO n 
2 307 ASN n 
2 308 GLU n 
2 309 ASN n 
2 310 PRO n 
2 311 ALA n 
2 312 HIS n 
2 313 LYS n 
2 314 SER n 
2 315 GLN n 
2 316 LEU n 
2 317 VAL n 
2 318 TRP n 
2 319 MET n 
2 320 ALA n 
2 321 CYS n 
2 322 HIS n 
2 323 SER n 
2 324 ALA n 
2 325 ALA n 
2 326 PHE n 
2 327 GLU n 
2 328 ASP n 
2 329 LEU n 
2 330 ARG n 
2 331 VAL n 
2 332 SER n 
2 333 SER n 
2 334 PHE n 
2 335 ILE n 
2 336 ARG n 
2 337 GLY n 
2 338 THR n 
2 339 LYS n 
2 340 VAL n 
2 341 VAL n 
2 342 PRO n 
2 343 ARG n 
2 344 GLY n 
2 345 LYS n 
2 346 LEU n 
2 347 SER n 
2 348 THR n 
2 349 ARG n 
2 350 GLY n 
2 351 VAL n 
2 352 GLN n 
2 353 ILE n 
2 354 ALA n 
2 355 SER n 
2 356 ASN n 
2 357 GLU n 
2 358 ASN n 
2 359 MET n 
2 360 GLU n 
2 361 THR n 
2 362 MET n 
2 363 GLU n 
2 364 SER n 
2 365 SER n 
2 366 THR n 
2 367 LEU n 
2 368 GLU n 
2 369 LEU n 
2 370 ARG n 
2 371 SER n 
2 372 ARG n 
2 373 TYR n 
2 374 TRP n 
2 375 ALA n 
2 376 ILE n 
2 377 ARG n 
2 378 THR n 
2 379 ARG n 
2 380 SER n 
2 381 GLY n 
2 382 GLY n 
2 383 ASN n 
2 384 THR n 
2 385 ASN n 
2 386 GLN n 
2 387 GLN n 
2 388 ARG n 
2 389 ALA n 
2 390 SER n 
2 391 SER n 
2 392 GLY n 
2 393 GLN n 
2 394 ILE n 
2 395 SER n 
2 396 ILE n 
2 397 GLN n 
2 398 PRO n 
2 399 THR n 
2 400 PHE n 
2 401 SER n 
2 402 VAL n 
2 403 GLN n 
2 404 ARG n 
2 405 ASN n 
2 406 LEU n 
2 407 PRO n 
2 408 PHE n 
2 409 ASP n 
2 410 ARG n 
2 411 PRO n 
2 412 THR n 
2 413 ILE n 
2 414 MET n 
2 415 ALA n 
2 416 ALA n 
2 417 PHE n 
2 418 THR n 
2 419 GLY n 
2 420 ASN n 
2 421 THR n 
2 422 GLU n 
2 423 GLY n 
2 424 ARG n 
2 425 THR n 
2 426 SER n 
2 427 ASP n 
2 428 MET n 
2 429 ARG n 
2 430 THR n 
2 431 GLU n 
2 432 ILE n 
2 433 ILE n 
2 434 ARG n 
2 435 LEU n 
2 436 MET n 
2 437 GLU n 
2 438 SER n 
2 439 ALA n 
2 440 ARG n 
2 441 PRO n 
2 442 GLU n 
2 443 ASP n 
2 444 VAL n 
2 445 SER n 
2 446 PHE n 
2 447 GLN n 
2 448 GLY n 
2 449 ARG n 
2 450 GLY n 
2 451 VAL n 
2 452 PHE n 
2 453 GLU n 
2 454 LEU n 
2 455 SER n 
2 456 ASP n 
2 457 GLU n 
2 458 LYS n 
2 459 ALA n 
2 460 THR n 
2 461 SER n 
2 462 PRO n 
2 463 ILE n 
2 464 VAL n 
2 465 PRO n 
2 466 SER n 
2 467 PHE n 
2 468 ASP n 
2 469 MET n 
2 470 SER n 
2 471 ASN n 
2 472 GLU n 
2 473 GLY n 
2 474 SER n 
2 475 TYR n 
2 476 PHE n 
2 477 PHE n 
2 478 GLY n 
2 479 ASP n 
2 480 ASN n 
2 481 ALA n 
2 482 GLU n 
2 483 GLU n 
2 484 TYR n 
2 485 ASP n 
2 486 ASN n 
2 487 LEU n 
2 488 GLU n 
2 489 HIS n 
2 490 HIS n 
2 491 HIS n 
2 492 HIS n 
2 493 HIS n 
2 494 HIS n 
# 
_entity_src_gen.entity_id                          2 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   494 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 NP 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Influenza A virus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     11320 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              1 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       12 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1IJK non-polymer         . 
'2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2R)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid' ? 'C27 H27 N O8'   
493.505 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
C     'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE" ? 'C9 H14 N3 O8 P' 323.197 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'    181.189 
U     'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE" ? 'C9 H13 N2 O9 P' 324.181 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   U   1   7   7   U   U   C . n 
A 1 2   C   2   8   8   C   C   C . n 
A 1 3   U   3   9   9   U   U   C . n 
A 1 4   C   4   10  10  C   C   C . n 
A 1 5   U   5   11  11  U   U   C . n 
A 1 6   C   6   12  12  C   6FM C . n 
A 1 7   U   7   13  ?   ?   ?   C . n 
A 1 8   C   8   14  ?   ?   ?   C . n 
A 1 9   U   9   15  ?   ?   ?   C . n 
A 1 10  C   10  16  ?   ?   ?   C . n 
A 1 11  U   11  17  ?   ?   ?   C . n 
A 1 12  C   12  18  ?   ?   ?   C . n 
B 1 1   U   1   1   1   U   U   D . n 
B 1 2   C   2   2   2   C   C   D . n 
B 1 3   U   3   3   3   U   U   D . n 
B 1 4   C   4   4   4   C   C   D . n 
B 1 5   U   5   5   5   U   U   D . n 
B 1 6   C   6   6   6   C   C   D . n 
B 1 7   U   7   7   ?   ?   ?   D . n 
B 1 8   C   8   8   ?   ?   ?   D . n 
B 1 9   U   9   9   ?   ?   ?   D . n 
B 1 10  C   10  10  ?   ?   ?   D . n 
B 1 11  U   11  11  ?   ?   ?   D . n 
B 1 12  C   12  12  ?   ?   ?   D . n 
C 2 1   HIS 1   13  ?   ?   ?   A . n 
C 2 2   MET 2   14  ?   ?   ?   A . n 
C 2 3   THR 3   15  15  THR THR A . n 
C 2 4   ASP 4   16  16  ASP ASP A . n 
C 2 5   GLY 5   17  17  GLY GLY A . n 
C 2 6   GLU 6   18  18  GLU GLU A . n 
C 2 7   ARG 7   19  19  ARG ARG A . n 
C 2 8   GLN 8   20  20  GLN GLN A . n 
C 2 9   ASN 9   21  21  ASN ASN A . n 
C 2 10  ALA 10  22  22  ALA ALA A . n 
C 2 11  THR 11  23  23  THR THR A . n 
C 2 12  GLU 12  24  24  GLU GLU A . n 
C 2 13  ILE 13  25  25  ILE ILE A . n 
C 2 14  ARG 14  26  26  ARG ARG A . n 
C 2 15  ALA 15  27  27  ALA ALA A . n 
C 2 16  SER 16  28  28  SER SER A . n 
C 2 17  VAL 17  29  29  VAL VAL A . n 
C 2 18  GLY 18  30  30  GLY GLY A . n 
C 2 19  LYS 19  31  31  LYS LYS A . n 
C 2 20  MET 20  32  32  MET MET A . n 
C 2 21  ILE 21  33  33  ILE ILE A . n 
C 2 22  ASP 22  34  34  ASP ASP A . n 
C 2 23  GLY 23  35  35  GLY GLY A . n 
C 2 24  ILE 24  36  36  ILE ILE A . n 
C 2 25  GLY 25  37  37  GLY GLY A . n 
C 2 26  ARG 26  38  38  ARG ARG A . n 
C 2 27  PHE 27  39  39  PHE PHE A . n 
C 2 28  TYR 28  40  40  TYR TYR A . n 
C 2 29  ILE 29  41  41  ILE ILE A . n 
C 2 30  GLN 30  42  42  GLN GLN A . n 
C 2 31  MET 31  43  43  MET MET A . n 
C 2 32  CYS 32  44  44  CYS CYS A . n 
C 2 33  THR 33  45  45  THR THR A . n 
C 2 34  GLU 34  46  46  GLU GLU A . n 
C 2 35  LEU 35  47  47  LEU LEU A . n 
C 2 36  LYS 36  48  48  LYS LYS A . n 
C 2 37  LEU 37  49  49  LEU LEU A . n 
C 2 38  SER 38  50  50  SER SER A . n 
C 2 39  ASP 39  51  51  ASP ASP A . n 
C 2 40  TYR 40  52  52  TYR TYR A . n 
C 2 41  GLU 41  53  53  GLU GLU A . n 
C 2 42  GLY 42  54  54  GLY GLY A . n 
C 2 43  ARG 43  55  55  ARG ARG A . n 
C 2 44  LEU 44  56  56  LEU LEU A . n 
C 2 45  ILE 45  57  57  ILE ILE A . n 
C 2 46  GLN 46  58  58  GLN GLN A . n 
C 2 47  ASN 47  59  59  ASN ASN A . n 
C 2 48  SER 48  60  60  SER SER A . n 
C 2 49  LEU 49  61  61  LEU LEU A . n 
C 2 50  THR 50  62  62  THR THR A . n 
C 2 51  ILE 51  63  63  ILE ILE A . n 
C 2 52  GLU 52  64  64  GLU GLU A . n 
C 2 53  ARG 53  65  65  ARG ARG A . n 
C 2 54  MET 54  66  66  MET MET A . n 
C 2 55  VAL 55  67  67  VAL VAL A . n 
C 2 56  LEU 56  68  68  LEU LEU A . n 
C 2 57  SER 57  69  69  SER SER A . n 
C 2 58  ALA 58  70  70  ALA ALA A . n 
C 2 59  PHE 59  71  71  PHE PHE A . n 
C 2 60  ASP 60  72  72  ASP ASP A . n 
C 2 61  GLU 61  73  73  GLU GLU A . n 
C 2 62  ARG 62  74  74  ARG ARG A . n 
C 2 63  ARG 63  75  75  ARG ARG A . n 
C 2 64  ASN 64  76  76  ASN ASN A . n 
C 2 65  LYS 65  77  77  LYS LYS A . n 
C 2 66  TYR 66  78  78  TYR TYR A . n 
C 2 67  LEU 67  79  79  LEU LEU A . n 
C 2 68  GLU 68  80  80  GLU GLU A . n 
C 2 69  GLU 69  81  81  GLU GLU A . n 
C 2 70  HIS 70  82  82  HIS HIS A . n 
C 2 71  PRO 71  83  83  PRO PRO A . n 
C 2 72  SER 72  84  84  SER SER A . n 
C 2 73  ALA 73  85  85  ALA ALA A . n 
C 2 74  GLY 74  86  86  GLY GLY A . n 
C 2 75  LYS 75  87  87  LYS LYS A . n 
C 2 76  ASP 76  88  88  ASP ASP A . n 
C 2 77  PRO 77  89  89  PRO PRO A . n 
C 2 78  LYS 78  90  90  LYS LYS A . n 
C 2 79  LYS 79  91  91  LYS LYS A . n 
C 2 80  THR 80  92  92  THR THR A . n 
C 2 81  GLY 81  93  93  GLY GLY A . n 
C 2 82  GLY 82  94  94  GLY GLY A . n 
C 2 83  PRO 83  95  95  PRO PRO A . n 
C 2 84  ILE 84  96  96  ILE ILE A . n 
C 2 85  TYR 85  97  97  TYR TYR A . n 
C 2 86  ARG 86  98  98  ARG ARG A . n 
C 2 87  ARG 87  99  99  ARG ARG A . n 
C 2 88  VAL 88  100 100 VAL VAL A . n 
C 2 89  ASP 89  101 101 ASP ASP A . n 
C 2 90  GLY 90  102 102 GLY GLY A . n 
C 2 91  LYS 91  103 103 LYS LYS A . n 
C 2 92  TRP 92  104 104 TRP TRP A . n 
C 2 93  ARG 93  105 105 ARG ARG A . n 
C 2 94  ARG 94  106 106 ARG ARG A . n 
C 2 95  GLU 95  107 107 GLU GLU A . n 
C 2 96  LEU 96  108 108 LEU LEU A . n 
C 2 97  ILE 97  109 109 ILE ILE A . n 
C 2 98  LEU 98  110 110 LEU LEU A . n 
C 2 99  TYR 99  111 111 TYR TYR A . n 
C 2 100 ASP 100 112 112 ASP ASP A . n 
C 2 101 LYS 101 113 113 LYS LYS A . n 
C 2 102 GLU 102 114 114 GLU GLU A . n 
C 2 103 GLU 103 115 115 GLU GLU A . n 
C 2 104 ILE 104 116 116 ILE ILE A . n 
C 2 105 ARG 105 117 117 ARG ARG A . n 
C 2 106 ARG 106 118 118 ARG ARG A . n 
C 2 107 ILE 107 119 119 ILE ILE A . n 
C 2 108 TRP 108 120 120 TRP TRP A . n 
C 2 109 ARG 109 121 121 ARG ARG A . n 
C 2 110 GLN 110 122 122 GLN GLN A . n 
C 2 111 ALA 111 123 123 ALA ALA A . n 
C 2 112 ASN 112 124 124 ASN ASN A . n 
C 2 113 ASN 113 125 125 ASN ASN A . n 
C 2 114 GLY 114 126 126 GLY GLY A . n 
C 2 115 ASP 115 127 127 ASP ASP A . n 
C 2 116 ASP 116 128 128 ASP ASP A . n 
C 2 117 ALA 117 129 129 ALA ALA A . n 
C 2 118 THR 118 130 130 THR THR A . n 
C 2 119 ALA 119 131 131 ALA ALA A . n 
C 2 120 GLY 120 132 132 GLY GLY A . n 
C 2 121 LEU 121 133 133 LEU LEU A . n 
C 2 122 THR 122 134 134 THR THR A . n 
C 2 123 HIS 123 135 135 HIS HIS A . n 
C 2 124 MET 124 136 136 MET MET A . n 
C 2 125 MET 125 137 137 MET MET A . n 
C 2 126 ILE 126 138 138 ILE ILE A . n 
C 2 127 TRP 127 139 139 TRP TRP A . n 
C 2 128 HIS 128 140 140 HIS HIS A . n 
C 2 129 SER 129 141 141 SER SER A . n 
C 2 130 ASN 130 142 142 ASN ASN A . n 
C 2 131 LEU 131 143 143 LEU LEU A . n 
C 2 132 ASN 132 144 144 ASN ASN A . n 
C 2 133 ASP 133 145 145 ASP ASP A . n 
C 2 134 ALA 134 146 146 ALA ALA A . n 
C 2 135 THR 135 147 147 THR THR A . n 
C 2 136 TYR 136 148 148 TYR TYR A . n 
C 2 137 GLN 137 149 149 GLN GLN A . n 
C 2 138 ARG 138 150 150 ARG ARG A . n 
C 2 139 THR 139 151 151 THR THR A . n 
C 2 140 ARG 140 152 152 ARG ARG A . n 
C 2 141 ALA 141 153 153 ALA ALA A . n 
C 2 142 LEU 142 154 154 LEU LEU A . n 
C 2 143 VAL 143 155 155 VAL VAL A . n 
C 2 144 ARG 144 156 156 ARG ARG A . n 
C 2 145 THR 145 157 157 THR THR A . n 
C 2 146 GLY 146 158 158 GLY GLY A . n 
C 2 147 MET 147 159 159 MET MET A . n 
C 2 148 ASP 148 160 160 ASP ASP A . n 
C 2 149 PRO 149 161 161 PRO PRO A . n 
C 2 150 ARG 150 162 162 ARG ARG A . n 
C 2 151 MET 151 163 163 MET MET A . n 
C 2 152 CYS 152 164 164 CYS CYS A . n 
C 2 153 SER 153 165 165 SER SER A . n 
C 2 154 LEU 154 166 166 LEU LEU A . n 
C 2 155 MET 155 167 167 MET MET A . n 
C 2 156 GLN 156 168 168 GLN GLN A . n 
C 2 157 GLY 157 169 169 GLY GLY A . n 
C 2 158 SER 158 170 170 SER SER A . n 
C 2 159 THR 159 171 171 THR THR A . n 
C 2 160 LEU 160 172 172 LEU LEU A . n 
C 2 161 PRO 161 173 173 PRO PRO A . n 
C 2 162 ARG 162 174 174 ARG ARG A . n 
C 2 163 ARG 163 175 175 ARG ARG A . n 
C 2 164 SER 164 176 176 SER SER A . n 
C 2 165 GLY 165 177 177 GLY GLY A . n 
C 2 166 ALA 166 178 178 ALA ALA A . n 
C 2 167 ALA 167 179 179 ALA ALA A . n 
C 2 168 GLY 168 180 180 GLY GLY A . n 
C 2 169 ALA 169 181 181 ALA ALA A . n 
C 2 170 ALA 170 182 182 ALA ALA A . n 
C 2 171 VAL 171 183 183 VAL VAL A . n 
C 2 172 LYS 172 184 184 LYS LYS A . n 
C 2 173 GLY 173 185 185 GLY GLY A . n 
C 2 174 VAL 174 186 186 VAL VAL A . n 
C 2 175 GLY 175 187 187 GLY GLY A . n 
C 2 176 THR 176 188 188 THR THR A . n 
C 2 177 MET 177 189 189 MET MET A . n 
C 2 178 VAL 178 190 190 VAL VAL A . n 
C 2 179 MET 179 191 191 MET MET A . n 
C 2 180 GLU 180 192 192 GLU GLU A . n 
C 2 181 LEU 181 193 193 LEU LEU A . n 
C 2 182 ILE 182 194 194 ILE ILE A . n 
C 2 183 ARG 183 195 195 ARG ARG A . n 
C 2 184 MET 184 196 196 MET MET A . n 
C 2 185 ILE 185 197 197 ILE ILE A . n 
C 2 186 LYS 186 198 198 LYS LYS A . n 
C 2 187 ARG 187 199 199 ARG ARG A . n 
C 2 188 GLY 188 200 200 GLY GLY A . n 
C 2 189 ILE 189 201 201 ILE ILE A . n 
C 2 190 ASN 190 202 202 ASN ASN A . n 
C 2 191 ASP 191 203 203 ASP ASP A . n 
C 2 192 ARG 192 204 204 ARG ARG A . n 
C 2 193 ASN 193 205 205 ASN ASN A . n 
C 2 194 PHE 194 206 206 PHE PHE A . n 
C 2 195 TRP 195 207 207 TRP TRP A . n 
C 2 196 ARG 196 208 208 ARG ARG A . n 
C 2 197 GLY 197 209 209 GLY GLY A . n 
C 2 198 GLU 198 210 210 GLU GLU A . n 
C 2 199 ASN 199 211 211 ASN ASN A . n 
C 2 200 GLY 200 212 212 GLY GLY A . n 
C 2 201 ARG 201 213 213 ARG ARG A . n 
C 2 202 ARG 202 214 214 ARG ARG A . n 
C 2 203 THR 203 215 215 THR THR A . n 
C 2 204 ARG 204 216 216 ARG ARG A . n 
C 2 205 ILE 205 217 217 ILE ILE A . n 
C 2 206 ALA 206 218 218 ALA ALA A . n 
C 2 207 TYR 207 219 219 TYR TYR A . n 
C 2 208 GLU 208 220 220 GLU GLU A . n 
C 2 209 ARG 209 221 221 ARG ARG A . n 
C 2 210 MET 210 222 222 MET MET A . n 
C 2 211 CYS 211 223 223 CYS CYS A . n 
C 2 212 ASN 212 224 224 ASN ASN A . n 
C 2 213 ILE 213 225 225 ILE ILE A . n 
C 2 214 LEU 214 226 226 LEU LEU A . n 
C 2 215 LYS 215 227 227 LYS LYS A . n 
C 2 216 GLY 216 228 228 GLY GLY A . n 
C 2 217 LYS 217 229 229 LYS LYS A . n 
C 2 218 PHE 218 230 230 PHE PHE A . n 
C 2 219 GLN 219 231 231 GLN GLN A . n 
C 2 220 THR 220 232 232 THR THR A . n 
C 2 221 ALA 221 233 233 ALA ALA A . n 
C 2 222 ALA 222 234 234 ALA ALA A . n 
C 2 223 GLN 223 235 235 GLN GLN A . n 
C 2 224 ARG 224 236 236 ARG ARG A . n 
C 2 225 THR 225 237 237 THR THR A . n 
C 2 226 MET 226 238 238 MET MET A . n 
C 2 227 VAL 227 239 239 VAL VAL A . n 
C 2 228 ASP 228 240 240 ASP ASP A . n 
C 2 229 GLN 229 241 241 GLN GLN A . n 
C 2 230 VAL 230 242 242 VAL VAL A . n 
C 2 231 ARG 231 243 243 ARG ARG A . n 
C 2 232 GLU 232 244 244 GLU GLU A . n 
C 2 233 SER 233 245 245 SER SER A . n 
C 2 234 ARG 234 246 246 ARG ARG A . n 
C 2 235 ASN 235 247 247 ASN ASN A . n 
C 2 236 PRO 236 248 248 PRO PRO A . n 
C 2 237 GLY 237 249 249 GLY GLY A . n 
C 2 238 ASN 238 250 250 ASN ASN A . n 
C 2 239 ALA 239 251 251 ALA ALA A . n 
C 2 240 GLU 240 252 252 GLU GLU A . n 
C 2 241 PHE 241 253 253 PHE PHE A . n 
C 2 242 GLU 242 254 254 GLU GLU A . n 
C 2 243 ASP 243 255 255 ASP ASP A . n 
C 2 244 LEU 244 256 256 LEU LEU A . n 
C 2 245 ILE 245 257 257 ILE ILE A . n 
C 2 246 PHE 246 258 258 PHE PHE A . n 
C 2 247 LEU 247 259 259 LEU LEU A . n 
C 2 248 ALA 248 260 260 ALA ALA A . n 
C 2 249 ARG 249 261 261 ARG ARG A . n 
C 2 250 SER 250 262 262 SER SER A . n 
C 2 251 ALA 251 263 263 ALA ALA A . n 
C 2 252 LEU 252 264 264 LEU LEU A . n 
C 2 253 ILE 253 265 265 ILE ILE A . n 
C 2 254 LEU 254 266 266 LEU LEU A . n 
C 2 255 ARG 255 267 267 ARG ARG A . n 
C 2 256 GLY 256 268 268 GLY GLY A . n 
C 2 257 SER 257 269 269 SER SER A . n 
C 2 258 VAL 258 270 270 VAL VAL A . n 
C 2 259 ALA 259 271 271 ALA ALA A . n 
C 2 260 HIS 260 272 272 HIS HIS A . n 
C 2 261 LYS 261 273 273 LYS LYS A . n 
C 2 262 SER 262 274 274 SER SER A . n 
C 2 263 CYS 263 275 275 CYS CYS A . n 
C 2 264 LEU 264 276 276 LEU LEU A . n 
C 2 265 PRO 265 277 277 PRO PRO A . n 
C 2 266 ALA 266 278 278 ALA ALA A . n 
C 2 267 CYS 267 279 279 CYS CYS A . n 
C 2 268 VAL 268 280 280 VAL VAL A . n 
C 2 269 TYR 269 281 281 TYR TYR A . n 
C 2 270 GLY 270 282 282 GLY GLY A . n 
C 2 271 SER 271 283 283 SER SER A . n 
C 2 272 ALA 272 284 284 ALA ALA A . n 
C 2 273 VAL 273 285 285 VAL VAL A . n 
C 2 274 ALA 274 286 286 ALA ALA A . n 
C 2 275 SER 275 287 287 SER SER A . n 
C 2 276 GLY 276 288 288 GLY GLY A . n 
C 2 277 TYR 277 289 289 TYR TYR A . n 
C 2 278 ASP 278 290 290 ASP ASP A . n 
C 2 279 PHE 279 291 291 PHE PHE A . n 
C 2 280 GLU 280 292 292 GLU GLU A . n 
C 2 281 ARG 281 293 293 ARG ARG A . n 
C 2 282 GLU 282 294 294 GLU GLU A . n 
C 2 283 GLY 283 295 295 GLY GLY A . n 
C 2 284 TYR 284 296 296 TYR TYR A . n 
C 2 285 SER 285 297 297 SER SER A . n 
C 2 286 LEU 286 298 298 LEU LEU A . n 
C 2 287 VAL 287 299 299 VAL VAL A . n 
C 2 288 GLY 288 300 300 GLY GLY A . n 
C 2 289 ILE 289 301 301 ILE ILE A . n 
C 2 290 ASP 290 302 302 ASP ASP A . n 
C 2 291 PRO 291 303 303 PRO PRO A . n 
C 2 292 PHE 292 304 304 PHE PHE A . n 
C 2 293 ARG 293 305 305 ARG ARG A . n 
C 2 294 LEU 294 306 306 LEU LEU A . n 
C 2 295 LEU 295 307 307 LEU LEU A . n 
C 2 296 GLN 296 308 308 GLN GLN A . n 
C 2 297 ASN 297 309 309 ASN ASN A . n 
C 2 298 SER 298 310 310 SER SER A . n 
C 2 299 GLN 299 311 311 GLN GLN A . n 
C 2 300 VAL 300 312 312 VAL VAL A . n 
C 2 301 TYR 301 313 313 TYR TYR A . n 
C 2 302 SER 302 314 314 SER SER A . n 
C 2 303 LEU 303 315 315 LEU LEU A . n 
C 2 304 ILE 304 316 316 ILE ILE A . n 
C 2 305 ARG 305 317 317 ARG ARG A . n 
C 2 306 PRO 306 318 318 PRO PRO A . n 
C 2 307 ASN 307 319 319 ASN ASN A . n 
C 2 308 GLU 308 320 320 GLU GLU A . n 
C 2 309 ASN 309 321 321 ASN ASN A . n 
C 2 310 PRO 310 322 322 PRO PRO A . n 
C 2 311 ALA 311 323 323 ALA ALA A . n 
C 2 312 HIS 312 324 324 HIS HIS A . n 
C 2 313 LYS 313 325 325 LYS LYS A . n 
C 2 314 SER 314 326 326 SER SER A . n 
C 2 315 GLN 315 327 327 GLN GLN A . n 
C 2 316 LEU 316 328 328 LEU LEU A . n 
C 2 317 VAL 317 329 329 VAL VAL A . n 
C 2 318 TRP 318 330 330 TRP TRP A . n 
C 2 319 MET 319 331 331 MET MET A . n 
C 2 320 ALA 320 332 332 ALA ALA A . n 
C 2 321 CYS 321 333 333 CYS CYS A . n 
C 2 322 HIS 322 334 334 HIS HIS A . n 
C 2 323 SER 323 335 335 SER SER A . n 
C 2 324 ALA 324 336 336 ALA ALA A . n 
C 2 325 ALA 325 337 337 ALA ALA A . n 
C 2 326 PHE 326 338 338 PHE PHE A . n 
C 2 327 GLU 327 339 339 GLU GLU A . n 
C 2 328 ASP 328 340 340 ASP ASP A . n 
C 2 329 LEU 329 341 341 LEU LEU A . n 
C 2 330 ARG 330 342 342 ARG ARG A . n 
C 2 331 VAL 331 343 343 VAL VAL A . n 
C 2 332 SER 332 344 344 SER SER A . n 
C 2 333 SER 333 345 345 SER SER A . n 
C 2 334 PHE 334 346 346 PHE PHE A . n 
C 2 335 ILE 335 347 347 ILE ILE A . n 
C 2 336 ARG 336 348 348 ARG ARG A . n 
C 2 337 GLY 337 349 349 GLY GLY A . n 
C 2 338 THR 338 350 350 THR THR A . n 
C 2 339 LYS 339 351 351 LYS LYS A . n 
C 2 340 VAL 340 352 352 VAL VAL A . n 
C 2 341 VAL 341 353 353 VAL VAL A . n 
C 2 342 PRO 342 354 354 PRO PRO A . n 
C 2 343 ARG 343 355 355 ARG ARG A . n 
C 2 344 GLY 344 356 356 GLY GLY A . n 
C 2 345 LYS 345 357 357 LYS LYS A . n 
C 2 346 LEU 346 358 358 LEU LEU A . n 
C 2 347 SER 347 359 359 SER SER A . n 
C 2 348 THR 348 360 360 THR THR A . n 
C 2 349 ARG 349 361 361 ARG ARG A . n 
C 2 350 GLY 350 362 362 GLY GLY A . n 
C 2 351 VAL 351 363 363 VAL VAL A . n 
C 2 352 GLN 352 364 364 GLN GLN A . n 
C 2 353 ILE 353 365 365 ILE ILE A . n 
C 2 354 ALA 354 366 366 ALA ALA A . n 
C 2 355 SER 355 367 367 SER SER A . n 
C 2 356 ASN 356 368 368 ASN ASN A . n 
C 2 357 GLU 357 369 369 GLU GLU A . n 
C 2 358 ASN 358 370 370 ASN ASN A . n 
C 2 359 MET 359 371 371 MET MET A . n 
C 2 360 GLU 360 372 372 GLU GLU A . n 
C 2 361 THR 361 373 373 THR THR A . n 
C 2 362 MET 362 374 374 MET MET A . n 
C 2 363 GLU 363 375 375 GLU GLU A . n 
C 2 364 SER 364 376 376 SER SER A . n 
C 2 365 SER 365 377 377 SER SER A . n 
C 2 366 THR 366 378 378 THR THR A . n 
C 2 367 LEU 367 379 379 LEU LEU A . n 
C 2 368 GLU 368 380 380 GLU GLU A . n 
C 2 369 LEU 369 381 381 LEU LEU A . n 
C 2 370 ARG 370 382 382 ARG ARG A . n 
C 2 371 SER 371 383 383 SER SER A . n 
C 2 372 ARG 372 384 384 ARG ARG A . n 
C 2 373 TYR 373 385 385 TYR TYR A . n 
C 2 374 TRP 374 386 386 TRP TRP A . n 
C 2 375 ALA 375 387 387 ALA ALA A . n 
C 2 376 ILE 376 388 388 ILE ILE A . n 
C 2 377 ARG 377 389 389 ARG ARG A . n 
C 2 378 THR 378 390 390 THR THR A . n 
C 2 379 ARG 379 391 391 ARG ARG A . n 
C 2 380 SER 380 392 392 SER SER A . n 
C 2 381 GLY 381 393 393 GLY GLY A . n 
C 2 382 GLY 382 394 394 GLY GLY A . n 
C 2 383 ASN 383 395 395 ASN ASN A . n 
C 2 384 THR 384 396 396 THR THR A . n 
C 2 385 ASN 385 397 397 ASN ASN A . n 
C 2 386 GLN 386 398 ?   ?   ?   A . n 
C 2 387 GLN 387 399 ?   ?   ?   A . n 
C 2 388 ARG 388 400 ?   ?   ?   A . n 
C 2 389 ALA 389 401 ?   ?   ?   A . n 
C 2 390 SER 390 402 ?   ?   ?   A . n 
C 2 391 SER 391 403 ?   ?   ?   A . n 
C 2 392 GLY 392 404 ?   ?   ?   A . n 
C 2 393 GLN 393 405 ?   ?   ?   A . n 
C 2 394 ILE 394 406 ?   ?   ?   A . n 
C 2 395 SER 395 407 ?   ?   ?   A . n 
C 2 396 ILE 396 408 ?   ?   ?   A . n 
C 2 397 GLN 397 409 ?   ?   ?   A . n 
C 2 398 PRO 398 410 ?   ?   ?   A . n 
C 2 399 THR 399 411 ?   ?   ?   A . n 
C 2 400 PHE 400 412 ?   ?   ?   A . n 
C 2 401 SER 401 413 ?   ?   ?   A . n 
C 2 402 VAL 402 414 ?   ?   ?   A . n 
C 2 403 GLN 403 415 ?   ?   ?   A . n 
C 2 404 ARG 404 416 ?   ?   ?   A . n 
C 2 405 ASN 405 417 ?   ?   ?   A . n 
C 2 406 LEU 406 418 ?   ?   ?   A . n 
C 2 407 PRO 407 419 ?   ?   ?   A . n 
C 2 408 PHE 408 420 ?   ?   ?   A . n 
C 2 409 ASP 409 421 ?   ?   ?   A . n 
C 2 410 ARG 410 422 ?   ?   ?   A . n 
C 2 411 PRO 411 423 ?   ?   ?   A . n 
C 2 412 THR 412 424 ?   ?   ?   A . n 
C 2 413 ILE 413 425 ?   ?   ?   A . n 
C 2 414 MET 414 426 ?   ?   ?   A . n 
C 2 415 ALA 415 427 ?   ?   ?   A . n 
C 2 416 ALA 416 428 ?   ?   ?   A . n 
C 2 417 PHE 417 429 ?   ?   ?   A . n 
C 2 418 THR 418 430 ?   ?   ?   A . n 
C 2 419 GLY 419 431 ?   ?   ?   A . n 
C 2 420 ASN 420 432 ?   ?   ?   A . n 
C 2 421 THR 421 433 ?   ?   ?   A . n 
C 2 422 GLU 422 434 ?   ?   ?   A . n 
C 2 423 GLY 423 435 ?   ?   ?   A . n 
C 2 424 ARG 424 436 ?   ?   ?   A . n 
C 2 425 THR 425 437 437 THR THR A . n 
C 2 426 SER 426 438 438 SER SER A . n 
C 2 427 ASP 427 439 439 ASP ASP A . n 
C 2 428 MET 428 440 440 MET MET A . n 
C 2 429 ARG 429 441 441 ARG ARG A . n 
C 2 430 THR 430 442 442 THR THR A . n 
C 2 431 GLU 431 443 443 GLU GLU A . n 
C 2 432 ILE 432 444 444 ILE ILE A . n 
C 2 433 ILE 433 445 445 ILE ILE A . n 
C 2 434 ARG 434 446 446 ARG ARG A . n 
C 2 435 LEU 435 447 447 LEU LEU A . n 
C 2 436 MET 436 448 448 MET MET A . n 
C 2 437 GLU 437 449 449 GLU GLU A . n 
C 2 438 SER 438 450 450 SER SER A . n 
C 2 439 ALA 439 451 451 ALA ALA A . n 
C 2 440 ARG 440 452 452 ARG ARG A . n 
C 2 441 PRO 441 453 453 PRO PRO A . n 
C 2 442 GLU 442 454 454 GLU GLU A . n 
C 2 443 ASP 443 455 455 ASP ASP A . n 
C 2 444 VAL 444 456 456 VAL VAL A . n 
C 2 445 SER 445 457 457 SER SER A . n 
C 2 446 PHE 446 458 458 PHE PHE A . n 
C 2 447 GLN 447 459 459 GLN GLN A . n 
C 2 448 GLY 448 460 460 GLY GLY A . n 
C 2 449 ARG 449 461 461 ARG ARG A . n 
C 2 450 GLY 450 462 462 GLY GLY A . n 
C 2 451 VAL 451 463 463 VAL VAL A . n 
C 2 452 PHE 452 464 464 PHE PHE A . n 
C 2 453 GLU 453 465 465 GLU GLU A . n 
C 2 454 LEU 454 466 466 LEU LEU A . n 
C 2 455 SER 455 467 467 SER SER A . n 
C 2 456 ASP 456 468 468 ASP ASP A . n 
C 2 457 GLU 457 469 469 GLU GLU A . n 
C 2 458 LYS 458 470 470 LYS LYS A . n 
C 2 459 ALA 459 471 471 ALA ALA A . n 
C 2 460 THR 460 472 472 THR THR A . n 
C 2 461 SER 461 473 473 SER SER A . n 
C 2 462 PRO 462 474 474 PRO PRO A . n 
C 2 463 ILE 463 475 475 ILE ILE A . n 
C 2 464 VAL 464 476 476 VAL VAL A . n 
C 2 465 PRO 465 477 477 PRO PRO A . n 
C 2 466 SER 466 478 478 SER SER A . n 
C 2 467 PHE 467 479 479 PHE PHE A . n 
C 2 468 ASP 468 480 ?   ?   ?   A . n 
C 2 469 MET 469 481 ?   ?   ?   A . n 
C 2 470 SER 470 482 ?   ?   ?   A . n 
C 2 471 ASN 471 483 ?   ?   ?   A . n 
C 2 472 GLU 472 484 484 GLU GLU A . n 
C 2 473 GLY 473 485 485 GLY GLY A . n 
C 2 474 SER 474 486 486 SER SER A . n 
C 2 475 TYR 475 487 487 TYR TYR A . n 
C 2 476 PHE 476 488 488 PHE PHE A . n 
C 2 477 PHE 477 489 489 PHE PHE A . n 
C 2 478 GLY 478 490 490 GLY GLY A . n 
C 2 479 ASP 479 491 ?   ?   ?   A . n 
C 2 480 ASN 480 492 ?   ?   ?   A . n 
C 2 481 ALA 481 493 ?   ?   ?   A . n 
C 2 482 GLU 482 494 ?   ?   ?   A . n 
C 2 483 GLU 483 495 ?   ?   ?   A . n 
C 2 484 TYR 484 496 ?   ?   ?   A . n 
C 2 485 ASP 485 497 ?   ?   ?   A . n 
C 2 486 ASN 486 498 ?   ?   ?   A . n 
C 2 487 LEU 487 499 ?   ?   ?   A . n 
C 2 488 GLU 488 500 ?   ?   ?   A . n 
C 2 489 HIS 489 501 ?   ?   ?   A . n 
C 2 490 HIS 490 502 ?   ?   ?   A . n 
C 2 491 HIS 491 503 ?   ?   ?   A . n 
C 2 492 HIS 492 504 ?   ?   ?   A . n 
C 2 493 HIS 493 505 ?   ?   ?   A . n 
C 2 494 HIS 494 506 ?   ?   ?   A . n 
D 2 1   HIS 1   13  ?   ?   ?   B . n 
D 2 2   MET 2   14  ?   ?   ?   B . n 
D 2 3   THR 3   15  ?   ?   ?   B . n 
D 2 4   ASP 4   16  ?   ?   ?   B . n 
D 2 5   GLY 5   17  ?   ?   ?   B . n 
D 2 6   GLU 6   18  ?   ?   ?   B . n 
D 2 7   ARG 7   19  ?   ?   ?   B . n 
D 2 8   GLN 8   20  ?   ?   ?   B . n 
D 2 9   ASN 9   21  ?   ?   ?   B . n 
D 2 10  ALA 10  22  ?   ?   ?   B . n 
D 2 11  THR 11  23  ?   ?   ?   B . n 
D 2 12  GLU 12  24  ?   ?   ?   B . n 
D 2 13  ILE 13  25  ?   ?   ?   B . n 
D 2 14  ARG 14  26  ?   ?   ?   B . n 
D 2 15  ALA 15  27  ?   ?   ?   B . n 
D 2 16  SER 16  28  ?   ?   ?   B . n 
D 2 17  VAL 17  29  ?   ?   ?   B . n 
D 2 18  GLY 18  30  ?   ?   ?   B . n 
D 2 19  LYS 19  31  ?   ?   ?   B . n 
D 2 20  MET 20  32  ?   ?   ?   B . n 
D 2 21  ILE 21  33  ?   ?   ?   B . n 
D 2 22  ASP 22  34  ?   ?   ?   B . n 
D 2 23  GLY 23  35  ?   ?   ?   B . n 
D 2 24  ILE 24  36  ?   ?   ?   B . n 
D 2 25  GLY 25  37  ?   ?   ?   B . n 
D 2 26  ARG 26  38  ?   ?   ?   B . n 
D 2 27  PHE 27  39  ?   ?   ?   B . n 
D 2 28  TYR 28  40  ?   ?   ?   B . n 
D 2 29  ILE 29  41  ?   ?   ?   B . n 
D 2 30  GLN 30  42  ?   ?   ?   B . n 
D 2 31  MET 31  43  ?   ?   ?   B . n 
D 2 32  CYS 32  44  ?   ?   ?   B . n 
D 2 33  THR 33  45  ?   ?   ?   B . n 
D 2 34  GLU 34  46  ?   ?   ?   B . n 
D 2 35  LEU 35  47  ?   ?   ?   B . n 
D 2 36  LYS 36  48  ?   ?   ?   B . n 
D 2 37  LEU 37  49  ?   ?   ?   B . n 
D 2 38  SER 38  50  ?   ?   ?   B . n 
D 2 39  ASP 39  51  ?   ?   ?   B . n 
D 2 40  TYR 40  52  ?   ?   ?   B . n 
D 2 41  GLU 41  53  ?   ?   ?   B . n 
D 2 42  GLY 42  54  ?   ?   ?   B . n 
D 2 43  ARG 43  55  ?   ?   ?   B . n 
D 2 44  LEU 44  56  ?   ?   ?   B . n 
D 2 45  ILE 45  57  ?   ?   ?   B . n 
D 2 46  GLN 46  58  ?   ?   ?   B . n 
D 2 47  ASN 47  59  ?   ?   ?   B . n 
D 2 48  SER 48  60  ?   ?   ?   B . n 
D 2 49  LEU 49  61  ?   ?   ?   B . n 
D 2 50  THR 50  62  ?   ?   ?   B . n 
D 2 51  ILE 51  63  ?   ?   ?   B . n 
D 2 52  GLU 52  64  ?   ?   ?   B . n 
D 2 53  ARG 53  65  ?   ?   ?   B . n 
D 2 54  MET 54  66  ?   ?   ?   B . n 
D 2 55  VAL 55  67  ?   ?   ?   B . n 
D 2 56  LEU 56  68  ?   ?   ?   B . n 
D 2 57  SER 57  69  ?   ?   ?   B . n 
D 2 58  ALA 58  70  ?   ?   ?   B . n 
D 2 59  PHE 59  71  ?   ?   ?   B . n 
D 2 60  ASP 60  72  ?   ?   ?   B . n 
D 2 61  GLU 61  73  ?   ?   ?   B . n 
D 2 62  ARG 62  74  ?   ?   ?   B . n 
D 2 63  ARG 63  75  ?   ?   ?   B . n 
D 2 64  ASN 64  76  ?   ?   ?   B . n 
D 2 65  LYS 65  77  ?   ?   ?   B . n 
D 2 66  TYR 66  78  ?   ?   ?   B . n 
D 2 67  LEU 67  79  ?   ?   ?   B . n 
D 2 68  GLU 68  80  ?   ?   ?   B . n 
D 2 69  GLU 69  81  ?   ?   ?   B . n 
D 2 70  HIS 70  82  ?   ?   ?   B . n 
D 2 71  PRO 71  83  ?   ?   ?   B . n 
D 2 72  SER 72  84  ?   ?   ?   B . n 
D 2 73  ALA 73  85  ?   ?   ?   B . n 
D 2 74  GLY 74  86  ?   ?   ?   B . n 
D 2 75  LYS 75  87  ?   ?   ?   B . n 
D 2 76  ASP 76  88  ?   ?   ?   B . n 
D 2 77  PRO 77  89  ?   ?   ?   B . n 
D 2 78  LYS 78  90  ?   ?   ?   B . n 
D 2 79  LYS 79  91  ?   ?   ?   B . n 
D 2 80  THR 80  92  ?   ?   ?   B . n 
D 2 81  GLY 81  93  ?   ?   ?   B . n 
D 2 82  GLY 82  94  ?   ?   ?   B . n 
D 2 83  PRO 83  95  ?   ?   ?   B . n 
D 2 84  ILE 84  96  ?   ?   ?   B . n 
D 2 85  TYR 85  97  ?   ?   ?   B . n 
D 2 86  ARG 86  98  ?   ?   ?   B . n 
D 2 87  ARG 87  99  ?   ?   ?   B . n 
D 2 88  VAL 88  100 ?   ?   ?   B . n 
D 2 89  ASP 89  101 ?   ?   ?   B . n 
D 2 90  GLY 90  102 ?   ?   ?   B . n 
D 2 91  LYS 91  103 ?   ?   ?   B . n 
D 2 92  TRP 92  104 ?   ?   ?   B . n 
D 2 93  ARG 93  105 ?   ?   ?   B . n 
D 2 94  ARG 94  106 ?   ?   ?   B . n 
D 2 95  GLU 95  107 ?   ?   ?   B . n 
D 2 96  LEU 96  108 ?   ?   ?   B . n 
D 2 97  ILE 97  109 ?   ?   ?   B . n 
D 2 98  LEU 98  110 ?   ?   ?   B . n 
D 2 99  TYR 99  111 ?   ?   ?   B . n 
D 2 100 ASP 100 112 ?   ?   ?   B . n 
D 2 101 LYS 101 113 ?   ?   ?   B . n 
D 2 102 GLU 102 114 ?   ?   ?   B . n 
D 2 103 GLU 103 115 ?   ?   ?   B . n 
D 2 104 ILE 104 116 ?   ?   ?   B . n 
D 2 105 ARG 105 117 ?   ?   ?   B . n 
D 2 106 ARG 106 118 ?   ?   ?   B . n 
D 2 107 ILE 107 119 ?   ?   ?   B . n 
D 2 108 TRP 108 120 ?   ?   ?   B . n 
D 2 109 ARG 109 121 ?   ?   ?   B . n 
D 2 110 GLN 110 122 ?   ?   ?   B . n 
D 2 111 ALA 111 123 ?   ?   ?   B . n 
D 2 112 ASN 112 124 ?   ?   ?   B . n 
D 2 113 ASN 113 125 ?   ?   ?   B . n 
D 2 114 GLY 114 126 ?   ?   ?   B . n 
D 2 115 ASP 115 127 ?   ?   ?   B . n 
D 2 116 ASP 116 128 ?   ?   ?   B . n 
D 2 117 ALA 117 129 ?   ?   ?   B . n 
D 2 118 THR 118 130 ?   ?   ?   B . n 
D 2 119 ALA 119 131 ?   ?   ?   B . n 
D 2 120 GLY 120 132 ?   ?   ?   B . n 
D 2 121 LEU 121 133 ?   ?   ?   B . n 
D 2 122 THR 122 134 ?   ?   ?   B . n 
D 2 123 HIS 123 135 ?   ?   ?   B . n 
D 2 124 MET 124 136 ?   ?   ?   B . n 
D 2 125 MET 125 137 ?   ?   ?   B . n 
D 2 126 ILE 126 138 ?   ?   ?   B . n 
D 2 127 TRP 127 139 ?   ?   ?   B . n 
D 2 128 HIS 128 140 ?   ?   ?   B . n 
D 2 129 SER 129 141 ?   ?   ?   B . n 
D 2 130 ASN 130 142 ?   ?   ?   B . n 
D 2 131 LEU 131 143 ?   ?   ?   B . n 
D 2 132 ASN 132 144 ?   ?   ?   B . n 
D 2 133 ASP 133 145 ?   ?   ?   B . n 
D 2 134 ALA 134 146 ?   ?   ?   B . n 
D 2 135 THR 135 147 ?   ?   ?   B . n 
D 2 136 TYR 136 148 ?   ?   ?   B . n 
D 2 137 GLN 137 149 ?   ?   ?   B . n 
D 2 138 ARG 138 150 ?   ?   ?   B . n 
D 2 139 THR 139 151 ?   ?   ?   B . n 
D 2 140 ARG 140 152 ?   ?   ?   B . n 
D 2 141 ALA 141 153 ?   ?   ?   B . n 
D 2 142 LEU 142 154 ?   ?   ?   B . n 
D 2 143 VAL 143 155 ?   ?   ?   B . n 
D 2 144 ARG 144 156 ?   ?   ?   B . n 
D 2 145 THR 145 157 ?   ?   ?   B . n 
D 2 146 GLY 146 158 ?   ?   ?   B . n 
D 2 147 MET 147 159 ?   ?   ?   B . n 
D 2 148 ASP 148 160 ?   ?   ?   B . n 
D 2 149 PRO 149 161 ?   ?   ?   B . n 
D 2 150 ARG 150 162 ?   ?   ?   B . n 
D 2 151 MET 151 163 ?   ?   ?   B . n 
D 2 152 CYS 152 164 ?   ?   ?   B . n 
D 2 153 SER 153 165 ?   ?   ?   B . n 
D 2 154 LEU 154 166 ?   ?   ?   B . n 
D 2 155 MET 155 167 ?   ?   ?   B . n 
D 2 156 GLN 156 168 ?   ?   ?   B . n 
D 2 157 GLY 157 169 ?   ?   ?   B . n 
D 2 158 SER 158 170 ?   ?   ?   B . n 
D 2 159 THR 159 171 ?   ?   ?   B . n 
D 2 160 LEU 160 172 ?   ?   ?   B . n 
D 2 161 PRO 161 173 ?   ?   ?   B . n 
D 2 162 ARG 162 174 ?   ?   ?   B . n 
D 2 163 ARG 163 175 ?   ?   ?   B . n 
D 2 164 SER 164 176 ?   ?   ?   B . n 
D 2 165 GLY 165 177 ?   ?   ?   B . n 
D 2 166 ALA 166 178 ?   ?   ?   B . n 
D 2 167 ALA 167 179 ?   ?   ?   B . n 
D 2 168 GLY 168 180 ?   ?   ?   B . n 
D 2 169 ALA 169 181 ?   ?   ?   B . n 
D 2 170 ALA 170 182 ?   ?   ?   B . n 
D 2 171 VAL 171 183 ?   ?   ?   B . n 
D 2 172 LYS 172 184 ?   ?   ?   B . n 
D 2 173 GLY 173 185 ?   ?   ?   B . n 
D 2 174 VAL 174 186 ?   ?   ?   B . n 
D 2 175 GLY 175 187 ?   ?   ?   B . n 
D 2 176 THR 176 188 ?   ?   ?   B . n 
D 2 177 MET 177 189 ?   ?   ?   B . n 
D 2 178 VAL 178 190 ?   ?   ?   B . n 
D 2 179 MET 179 191 ?   ?   ?   B . n 
D 2 180 GLU 180 192 ?   ?   ?   B . n 
D 2 181 LEU 181 193 ?   ?   ?   B . n 
D 2 182 ILE 182 194 ?   ?   ?   B . n 
D 2 183 ARG 183 195 ?   ?   ?   B . n 
D 2 184 MET 184 196 ?   ?   ?   B . n 
D 2 185 ILE 185 197 ?   ?   ?   B . n 
D 2 186 LYS 186 198 ?   ?   ?   B . n 
D 2 187 ARG 187 199 ?   ?   ?   B . n 
D 2 188 GLY 188 200 ?   ?   ?   B . n 
D 2 189 ILE 189 201 ?   ?   ?   B . n 
D 2 190 ASN 190 202 ?   ?   ?   B . n 
D 2 191 ASP 191 203 ?   ?   ?   B . n 
D 2 192 ARG 192 204 ?   ?   ?   B . n 
D 2 193 ASN 193 205 ?   ?   ?   B . n 
D 2 194 PHE 194 206 ?   ?   ?   B . n 
D 2 195 TRP 195 207 ?   ?   ?   B . n 
D 2 196 ARG 196 208 ?   ?   ?   B . n 
D 2 197 GLY 197 209 ?   ?   ?   B . n 
D 2 198 GLU 198 210 ?   ?   ?   B . n 
D 2 199 ASN 199 211 ?   ?   ?   B . n 
D 2 200 GLY 200 212 ?   ?   ?   B . n 
D 2 201 ARG 201 213 ?   ?   ?   B . n 
D 2 202 ARG 202 214 ?   ?   ?   B . n 
D 2 203 THR 203 215 ?   ?   ?   B . n 
D 2 204 ARG 204 216 ?   ?   ?   B . n 
D 2 205 ILE 205 217 ?   ?   ?   B . n 
D 2 206 ALA 206 218 ?   ?   ?   B . n 
D 2 207 TYR 207 219 ?   ?   ?   B . n 
D 2 208 GLU 208 220 ?   ?   ?   B . n 
D 2 209 ARG 209 221 ?   ?   ?   B . n 
D 2 210 MET 210 222 ?   ?   ?   B . n 
D 2 211 CYS 211 223 ?   ?   ?   B . n 
D 2 212 ASN 212 224 ?   ?   ?   B . n 
D 2 213 ILE 213 225 ?   ?   ?   B . n 
D 2 214 LEU 214 226 ?   ?   ?   B . n 
D 2 215 LYS 215 227 ?   ?   ?   B . n 
D 2 216 GLY 216 228 ?   ?   ?   B . n 
D 2 217 LYS 217 229 ?   ?   ?   B . n 
D 2 218 PHE 218 230 ?   ?   ?   B . n 
D 2 219 GLN 219 231 ?   ?   ?   B . n 
D 2 220 THR 220 232 ?   ?   ?   B . n 
D 2 221 ALA 221 233 ?   ?   ?   B . n 
D 2 222 ALA 222 234 ?   ?   ?   B . n 
D 2 223 GLN 223 235 ?   ?   ?   B . n 
D 2 224 ARG 224 236 ?   ?   ?   B . n 
D 2 225 THR 225 237 ?   ?   ?   B . n 
D 2 226 MET 226 238 ?   ?   ?   B . n 
D 2 227 VAL 227 239 ?   ?   ?   B . n 
D 2 228 ASP 228 240 ?   ?   ?   B . n 
D 2 229 GLN 229 241 ?   ?   ?   B . n 
D 2 230 VAL 230 242 ?   ?   ?   B . n 
D 2 231 ARG 231 243 ?   ?   ?   B . n 
D 2 232 GLU 232 244 ?   ?   ?   B . n 
D 2 233 SER 233 245 ?   ?   ?   B . n 
D 2 234 ARG 234 246 ?   ?   ?   B . n 
D 2 235 ASN 235 247 ?   ?   ?   B . n 
D 2 236 PRO 236 248 ?   ?   ?   B . n 
D 2 237 GLY 237 249 ?   ?   ?   B . n 
D 2 238 ASN 238 250 ?   ?   ?   B . n 
D 2 239 ALA 239 251 ?   ?   ?   B . n 
D 2 240 GLU 240 252 ?   ?   ?   B . n 
D 2 241 PHE 241 253 ?   ?   ?   B . n 
D 2 242 GLU 242 254 ?   ?   ?   B . n 
D 2 243 ASP 243 255 ?   ?   ?   B . n 
D 2 244 LEU 244 256 ?   ?   ?   B . n 
D 2 245 ILE 245 257 ?   ?   ?   B . n 
D 2 246 PHE 246 258 ?   ?   ?   B . n 
D 2 247 LEU 247 259 ?   ?   ?   B . n 
D 2 248 ALA 248 260 ?   ?   ?   B . n 
D 2 249 ARG 249 261 ?   ?   ?   B . n 
D 2 250 SER 250 262 ?   ?   ?   B . n 
D 2 251 ALA 251 263 ?   ?   ?   B . n 
D 2 252 LEU 252 264 ?   ?   ?   B . n 
D 2 253 ILE 253 265 ?   ?   ?   B . n 
D 2 254 LEU 254 266 ?   ?   ?   B . n 
D 2 255 ARG 255 267 ?   ?   ?   B . n 
D 2 256 GLY 256 268 ?   ?   ?   B . n 
D 2 257 SER 257 269 ?   ?   ?   B . n 
D 2 258 VAL 258 270 ?   ?   ?   B . n 
D 2 259 ALA 259 271 ?   ?   ?   B . n 
D 2 260 HIS 260 272 ?   ?   ?   B . n 
D 2 261 LYS 261 273 ?   ?   ?   B . n 
D 2 262 SER 262 274 ?   ?   ?   B . n 
D 2 263 CYS 263 275 ?   ?   ?   B . n 
D 2 264 LEU 264 276 ?   ?   ?   B . n 
D 2 265 PRO 265 277 ?   ?   ?   B . n 
D 2 266 ALA 266 278 ?   ?   ?   B . n 
D 2 267 CYS 267 279 ?   ?   ?   B . n 
D 2 268 VAL 268 280 ?   ?   ?   B . n 
D 2 269 TYR 269 281 ?   ?   ?   B . n 
D 2 270 GLY 270 282 ?   ?   ?   B . n 
D 2 271 SER 271 283 ?   ?   ?   B . n 
D 2 272 ALA 272 284 ?   ?   ?   B . n 
D 2 273 VAL 273 285 ?   ?   ?   B . n 
D 2 274 ALA 274 286 ?   ?   ?   B . n 
D 2 275 SER 275 287 ?   ?   ?   B . n 
D 2 276 GLY 276 288 ?   ?   ?   B . n 
D 2 277 TYR 277 289 ?   ?   ?   B . n 
D 2 278 ASP 278 290 ?   ?   ?   B . n 
D 2 279 PHE 279 291 ?   ?   ?   B . n 
D 2 280 GLU 280 292 ?   ?   ?   B . n 
D 2 281 ARG 281 293 ?   ?   ?   B . n 
D 2 282 GLU 282 294 ?   ?   ?   B . n 
D 2 283 GLY 283 295 ?   ?   ?   B . n 
D 2 284 TYR 284 296 ?   ?   ?   B . n 
D 2 285 SER 285 297 ?   ?   ?   B . n 
D 2 286 LEU 286 298 ?   ?   ?   B . n 
D 2 287 VAL 287 299 ?   ?   ?   B . n 
D 2 288 GLY 288 300 ?   ?   ?   B . n 
D 2 289 ILE 289 301 ?   ?   ?   B . n 
D 2 290 ASP 290 302 ?   ?   ?   B . n 
D 2 291 PRO 291 303 ?   ?   ?   B . n 
D 2 292 PHE 292 304 ?   ?   ?   B . n 
D 2 293 ARG 293 305 ?   ?   ?   B . n 
D 2 294 LEU 294 306 ?   ?   ?   B . n 
D 2 295 LEU 295 307 ?   ?   ?   B . n 
D 2 296 GLN 296 308 ?   ?   ?   B . n 
D 2 297 ASN 297 309 ?   ?   ?   B . n 
D 2 298 SER 298 310 ?   ?   ?   B . n 
D 2 299 GLN 299 311 ?   ?   ?   B . n 
D 2 300 VAL 300 312 ?   ?   ?   B . n 
D 2 301 TYR 301 313 ?   ?   ?   B . n 
D 2 302 SER 302 314 ?   ?   ?   B . n 
D 2 303 LEU 303 315 ?   ?   ?   B . n 
D 2 304 ILE 304 316 ?   ?   ?   B . n 
D 2 305 ARG 305 317 ?   ?   ?   B . n 
D 2 306 PRO 306 318 ?   ?   ?   B . n 
D 2 307 ASN 307 319 ?   ?   ?   B . n 
D 2 308 GLU 308 320 ?   ?   ?   B . n 
D 2 309 ASN 309 321 ?   ?   ?   B . n 
D 2 310 PRO 310 322 ?   ?   ?   B . n 
D 2 311 ALA 311 323 ?   ?   ?   B . n 
D 2 312 HIS 312 324 ?   ?   ?   B . n 
D 2 313 LYS 313 325 ?   ?   ?   B . n 
D 2 314 SER 314 326 ?   ?   ?   B . n 
D 2 315 GLN 315 327 ?   ?   ?   B . n 
D 2 316 LEU 316 328 ?   ?   ?   B . n 
D 2 317 VAL 317 329 ?   ?   ?   B . n 
D 2 318 TRP 318 330 ?   ?   ?   B . n 
D 2 319 MET 319 331 ?   ?   ?   B . n 
D 2 320 ALA 320 332 ?   ?   ?   B . n 
D 2 321 CYS 321 333 ?   ?   ?   B . n 
D 2 322 HIS 322 334 ?   ?   ?   B . n 
D 2 323 SER 323 335 ?   ?   ?   B . n 
D 2 324 ALA 324 336 ?   ?   ?   B . n 
D 2 325 ALA 325 337 ?   ?   ?   B . n 
D 2 326 PHE 326 338 ?   ?   ?   B . n 
D 2 327 GLU 327 339 ?   ?   ?   B . n 
D 2 328 ASP 328 340 ?   ?   ?   B . n 
D 2 329 LEU 329 341 ?   ?   ?   B . n 
D 2 330 ARG 330 342 ?   ?   ?   B . n 
D 2 331 VAL 331 343 ?   ?   ?   B . n 
D 2 332 SER 332 344 ?   ?   ?   B . n 
D 2 333 SER 333 345 ?   ?   ?   B . n 
D 2 334 PHE 334 346 ?   ?   ?   B . n 
D 2 335 ILE 335 347 ?   ?   ?   B . n 
D 2 336 ARG 336 348 ?   ?   ?   B . n 
D 2 337 GLY 337 349 ?   ?   ?   B . n 
D 2 338 THR 338 350 ?   ?   ?   B . n 
D 2 339 LYS 339 351 ?   ?   ?   B . n 
D 2 340 VAL 340 352 ?   ?   ?   B . n 
D 2 341 VAL 341 353 ?   ?   ?   B . n 
D 2 342 PRO 342 354 ?   ?   ?   B . n 
D 2 343 ARG 343 355 ?   ?   ?   B . n 
D 2 344 GLY 344 356 ?   ?   ?   B . n 
D 2 345 LYS 345 357 ?   ?   ?   B . n 
D 2 346 LEU 346 358 ?   ?   ?   B . n 
D 2 347 SER 347 359 ?   ?   ?   B . n 
D 2 348 THR 348 360 ?   ?   ?   B . n 
D 2 349 ARG 349 361 ?   ?   ?   B . n 
D 2 350 GLY 350 362 ?   ?   ?   B . n 
D 2 351 VAL 351 363 ?   ?   ?   B . n 
D 2 352 GLN 352 364 ?   ?   ?   B . n 
D 2 353 ILE 353 365 ?   ?   ?   B . n 
D 2 354 ALA 354 366 ?   ?   ?   B . n 
D 2 355 SER 355 367 ?   ?   ?   B . n 
D 2 356 ASN 356 368 ?   ?   ?   B . n 
D 2 357 GLU 357 369 ?   ?   ?   B . n 
D 2 358 ASN 358 370 ?   ?   ?   B . n 
D 2 359 MET 359 371 ?   ?   ?   B . n 
D 2 360 GLU 360 372 ?   ?   ?   B . n 
D 2 361 THR 361 373 ?   ?   ?   B . n 
D 2 362 MET 362 374 ?   ?   ?   B . n 
D 2 363 GLU 363 375 ?   ?   ?   B . n 
D 2 364 SER 364 376 ?   ?   ?   B . n 
D 2 365 SER 365 377 ?   ?   ?   B . n 
D 2 366 THR 366 378 ?   ?   ?   B . n 
D 2 367 LEU 367 379 ?   ?   ?   B . n 
D 2 368 GLU 368 380 ?   ?   ?   B . n 
D 2 369 LEU 369 381 ?   ?   ?   B . n 
D 2 370 ARG 370 382 ?   ?   ?   B . n 
D 2 371 SER 371 383 ?   ?   ?   B . n 
D 2 372 ARG 372 384 ?   ?   ?   B . n 
D 2 373 TYR 373 385 ?   ?   ?   B . n 
D 2 374 TRP 374 386 ?   ?   ?   B . n 
D 2 375 ALA 375 387 ?   ?   ?   B . n 
D 2 376 ILE 376 388 ?   ?   ?   B . n 
D 2 377 ARG 377 389 ?   ?   ?   B . n 
D 2 378 THR 378 390 ?   ?   ?   B . n 
D 2 379 ARG 379 391 ?   ?   ?   B . n 
D 2 380 SER 380 392 ?   ?   ?   B . n 
D 2 381 GLY 381 393 ?   ?   ?   B . n 
D 2 382 GLY 382 394 ?   ?   ?   B . n 
D 2 383 ASN 383 395 ?   ?   ?   B . n 
D 2 384 THR 384 396 ?   ?   ?   B . n 
D 2 385 ASN 385 397 ?   ?   ?   B . n 
D 2 386 GLN 386 398 ?   ?   ?   B . n 
D 2 387 GLN 387 399 ?   ?   ?   B . n 
D 2 388 ARG 388 400 ?   ?   ?   B . n 
D 2 389 ALA 389 401 ?   ?   ?   B . n 
D 2 390 SER 390 402 402 SER SER B . n 
D 2 391 SER 391 403 403 SER SER B . n 
D 2 392 GLY 392 404 404 GLY GLY B . n 
D 2 393 GLN 393 405 405 GLN GLN B . n 
D 2 394 ILE 394 406 406 ILE ILE B . n 
D 2 395 SER 395 407 407 SER SER B . n 
D 2 396 ILE 396 408 408 ILE ILE B . n 
D 2 397 GLN 397 409 409 GLN GLN B . n 
D 2 398 PRO 398 410 410 PRO PRO B . n 
D 2 399 THR 399 411 411 THR THR B . n 
D 2 400 PHE 400 412 412 PHE PHE B . n 
D 2 401 SER 401 413 413 SER SER B . n 
D 2 402 VAL 402 414 414 VAL VAL B . n 
D 2 403 GLN 403 415 415 GLN GLN B . n 
D 2 404 ARG 404 416 416 ARG ARG B . n 
D 2 405 ASN 405 417 417 ASN ASN B . n 
D 2 406 LEU 406 418 418 LEU LEU B . n 
D 2 407 PRO 407 419 419 PRO PRO B . n 
D 2 408 PHE 408 420 420 PHE PHE B . n 
D 2 409 ASP 409 421 421 ASP ASP B . n 
D 2 410 ARG 410 422 422 ARG ARG B . n 
D 2 411 PRO 411 423 423 PRO PRO B . n 
D 2 412 THR 412 424 424 THR THR B . n 
D 2 413 ILE 413 425 425 ILE ILE B . n 
D 2 414 MET 414 426 426 MET MET B . n 
D 2 415 ALA 415 427 427 ALA ALA B . n 
D 2 416 ALA 416 428 428 ALA ALA B . n 
D 2 417 PHE 417 429 429 PHE PHE B . n 
D 2 418 THR 418 430 ?   ?   ?   B . n 
D 2 419 GLY 419 431 ?   ?   ?   B . n 
D 2 420 ASN 420 432 ?   ?   ?   B . n 
D 2 421 THR 421 433 ?   ?   ?   B . n 
D 2 422 GLU 422 434 ?   ?   ?   B . n 
D 2 423 GLY 423 435 ?   ?   ?   B . n 
D 2 424 ARG 424 436 ?   ?   ?   B . n 
D 2 425 THR 425 437 ?   ?   ?   B . n 
D 2 426 SER 426 438 ?   ?   ?   B . n 
D 2 427 ASP 427 439 ?   ?   ?   B . n 
D 2 428 MET 428 440 ?   ?   ?   B . n 
D 2 429 ARG 429 441 ?   ?   ?   B . n 
D 2 430 THR 430 442 ?   ?   ?   B . n 
D 2 431 GLU 431 443 ?   ?   ?   B . n 
D 2 432 ILE 432 444 ?   ?   ?   B . n 
D 2 433 ILE 433 445 ?   ?   ?   B . n 
D 2 434 ARG 434 446 ?   ?   ?   B . n 
D 2 435 LEU 435 447 ?   ?   ?   B . n 
D 2 436 MET 436 448 ?   ?   ?   B . n 
D 2 437 GLU 437 449 ?   ?   ?   B . n 
D 2 438 SER 438 450 ?   ?   ?   B . n 
D 2 439 ALA 439 451 ?   ?   ?   B . n 
D 2 440 ARG 440 452 ?   ?   ?   B . n 
D 2 441 PRO 441 453 ?   ?   ?   B . n 
D 2 442 GLU 442 454 ?   ?   ?   B . n 
D 2 443 ASP 443 455 ?   ?   ?   B . n 
D 2 444 VAL 444 456 ?   ?   ?   B . n 
D 2 445 SER 445 457 ?   ?   ?   B . n 
D 2 446 PHE 446 458 ?   ?   ?   B . n 
D 2 447 GLN 447 459 ?   ?   ?   B . n 
D 2 448 GLY 448 460 ?   ?   ?   B . n 
D 2 449 ARG 449 461 ?   ?   ?   B . n 
D 2 450 GLY 450 462 ?   ?   ?   B . n 
D 2 451 VAL 451 463 ?   ?   ?   B . n 
D 2 452 PHE 452 464 ?   ?   ?   B . n 
D 2 453 GLU 453 465 ?   ?   ?   B . n 
D 2 454 LEU 454 466 ?   ?   ?   B . n 
D 2 455 SER 455 467 ?   ?   ?   B . n 
D 2 456 ASP 456 468 ?   ?   ?   B . n 
D 2 457 GLU 457 469 ?   ?   ?   B . n 
D 2 458 LYS 458 470 ?   ?   ?   B . n 
D 2 459 ALA 459 471 ?   ?   ?   B . n 
D 2 460 THR 460 472 ?   ?   ?   B . n 
D 2 461 SER 461 473 ?   ?   ?   B . n 
D 2 462 PRO 462 474 ?   ?   ?   B . n 
D 2 463 ILE 463 475 ?   ?   ?   B . n 
D 2 464 VAL 464 476 ?   ?   ?   B . n 
D 2 465 PRO 465 477 ?   ?   ?   B . n 
D 2 466 SER 466 478 ?   ?   ?   B . n 
D 2 467 PHE 467 479 ?   ?   ?   B . n 
D 2 468 ASP 468 480 ?   ?   ?   B . n 
D 2 469 MET 469 481 ?   ?   ?   B . n 
D 2 470 SER 470 482 ?   ?   ?   B . n 
D 2 471 ASN 471 483 ?   ?   ?   B . n 
D 2 472 GLU 472 484 ?   ?   ?   B . n 
D 2 473 GLY 473 485 ?   ?   ?   B . n 
D 2 474 SER 474 486 ?   ?   ?   B . n 
D 2 475 TYR 475 487 ?   ?   ?   B . n 
D 2 476 PHE 476 488 ?   ?   ?   B . n 
D 2 477 PHE 477 489 ?   ?   ?   B . n 
D 2 478 GLY 478 490 ?   ?   ?   B . n 
D 2 479 ASP 479 491 ?   ?   ?   B . n 
D 2 480 ASN 480 492 ?   ?   ?   B . n 
D 2 481 ALA 481 493 ?   ?   ?   B . n 
D 2 482 GLU 482 494 ?   ?   ?   B . n 
D 2 483 GLU 483 495 ?   ?   ?   B . n 
D 2 484 TYR 484 496 ?   ?   ?   B . n 
D 2 485 ASP 485 497 ?   ?   ?   B . n 
D 2 486 ASN 486 498 ?   ?   ?   B . n 
D 2 487 LEU 487 499 ?   ?   ?   B . n 
D 2 488 GLU 488 500 ?   ?   ?   B . n 
D 2 489 HIS 489 501 ?   ?   ?   B . n 
D 2 490 HIS 490 502 ?   ?   ?   B . n 
D 2 491 HIS 491 503 ?   ?   ?   B . n 
D 2 492 HIS 492 504 ?   ?   ?   B . n 
D 2 493 HIS 493 505 ?   ?   ?   B . n 
D 2 494 HIS 494 506 ?   ?   ?   B . n 
# 
_pdbx_nonpoly_scheme.asym_id         E 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          A1IJK 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     101 
_pdbx_nonpoly_scheme.auth_seq_num    12 
_pdbx_nonpoly_scheme.pdb_mon_id      A1IJK 
_pdbx_nonpoly_scheme.auth_mon_id     6FM 
_pdbx_nonpoly_scheme.pdb_strand_id   C 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_pdbx_unobs_or_zero_occ_atoms.id               1 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id     C 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id     C 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id      12 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id     OP2 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id     ? 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id    A 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id    C 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id     6 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id    OP2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GAP 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GAP 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GAP 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9GAP 
_struct.title                        
'CryoEM structure of influenza A RNP-like particle double-stranded assembled with a 12-mer RNA.' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GAP 
_struct_keywords.text            'Nucleoprotein, RNA, complex, RNP-like, influenza virus, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9GAP         9GAP   ? 1 ? 1  
2 UNP Q1K9H2_I33A0 Q1K9H2 ? 2 
;TDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGG
PIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPR
RSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAEFE
DLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMACH
SAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTFSV
QRNLPFDRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDNAE
EYDN
;
15 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9GAP C 1 ? 12  ? 9GAP   7  ? 18  ? 7  18  
2 1 9GAP D 1 ? 12  ? 9GAP   1  ? 12  ? 1  12  
3 2 9GAP A 3 ? 486 ? Q1K9H2 15 ? 498 ? 15 498 
4 2 9GAP B 3 ? 486 ? Q1K9H2 15 ? 498 ? 15 498 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 9GAP HIS A 1   ? UNP Q1K9H2 ? ? 'expression tag' 13  1  
3 9GAP MET A 2   ? UNP Q1K9H2 ? ? 'expression tag' 14  2  
3 9GAP LEU A 487 ? UNP Q1K9H2 ? ? 'expression tag' 499 3  
3 9GAP GLU A 488 ? UNP Q1K9H2 ? ? 'expression tag' 500 4  
3 9GAP HIS A 489 ? UNP Q1K9H2 ? ? 'expression tag' 501 5  
3 9GAP HIS A 490 ? UNP Q1K9H2 ? ? 'expression tag' 502 6  
3 9GAP HIS A 491 ? UNP Q1K9H2 ? ? 'expression tag' 503 7  
3 9GAP HIS A 492 ? UNP Q1K9H2 ? ? 'expression tag' 504 8  
3 9GAP HIS A 493 ? UNP Q1K9H2 ? ? 'expression tag' 505 9  
3 9GAP HIS A 494 ? UNP Q1K9H2 ? ? 'expression tag' 506 10 
4 9GAP HIS B 1   ? UNP Q1K9H2 ? ? 'expression tag' 13  11 
4 9GAP MET B 2   ? UNP Q1K9H2 ? ? 'expression tag' 14  12 
4 9GAP LEU B 487 ? UNP Q1K9H2 ? ? 'expression tag' 499 13 
4 9GAP GLU B 488 ? UNP Q1K9H2 ? ? 'expression tag' 500 14 
4 9GAP HIS B 489 ? UNP Q1K9H2 ? ? 'expression tag' 501 15 
4 9GAP HIS B 490 ? UNP Q1K9H2 ? ? 'expression tag' 502 16 
4 9GAP HIS B 491 ? UNP Q1K9H2 ? ? 'expression tag' 503 17 
4 9GAP HIS B 492 ? UNP Q1K9H2 ? ? 'expression tag' 504 18 
4 9GAP HIS B 493 ? UNP Q1K9H2 ? ? 'expression tag' 505 19 
4 9GAP HIS B 494 ? UNP Q1K9H2 ? ? 'expression tag' 506 20 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1  A,B,C,D,E 
1 2  A,B,C,D,E 
1 3  A,B,C,D,E 
1 4  A,B,C,D,E 
1 5  A,B,C,D,E 
1 6  A,B,C,D,E 
1 7  A,B,C,D,E 
1 8  A,B,C,D,E 
1 9  A,B,C,D,E 
1 10 A,B,C,D,E 
1 11 A,B,C,D,E 
1 12 A,B,C,D,E 
1 13 A,B,C,D,E 
1 14 A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1  'identity operation'       1_555 x,y,z 1.000000  0.000000  0.000000  0.00000   -0.000000 1.000000  -0.000000 0.00000   
-0.000000 0.000000  1.000000 0.00000   
2  'point symmetry operation' ?     ?     -0.991649 0.128969  0.000000  426.55375 -0.128969 -0.991649 0.000000  485.62136 0.000000 
0.000000  1.000000 -72.00012 
3  'point symmetry operation' ?     ?     -0.423568 0.905864  -0.000000 118.55415 -0.905864 -0.423568 0.000000  533.43985 0.000000 
0.000000  1.000000 -47.99995 
4  'point symmetry operation' ?     ?     0.536858  0.843672  -0.000000 -87.14112 -0.843672 0.536858  -0.000000 299.26075 0.000000 
0.000000  1.000000 -23.99994 
5  'point symmetry operation' ?     ?     0.536858  -0.843673 0.000000  299.26083 0.843673  0.536858  -0.000000 -87.14133 0.000000 
0.000000  1.000000 24.00009  
6  'point symmetry operation' ?     ?     -0.423568 -0.905864 -0.000000 533.43988 0.905864  -0.423568 -0.000000 118.55394 
-0.000000 -0.000000 1.000000 47.99993  
7  'point symmetry operation' ?     ?     -0.991649 -0.128968 0.000000  485.62108 0.128968  -0.991649 -0.000000 426.55390 0.000000 
-0.000000 1.000000 71.99967  
8  'point symmetry operation' ?     ?     0.991649  -0.128969 0.000000  31.44624  0.128969  0.991649  0.000000  -27.62177 
-0.000000 -0.000000 1.000000 -72.00008 
9  'point symmetry operation' ?     ?     0.423568  -0.905865 0.000000  339.44589 0.905865  0.423568  -0.000000 -75.43997 0.000000 
0.000000  1.000000 -47.99987 
10 'point symmetry operation' ?     ?     -0.536858 -0.843672 -0.000000 545.14167 0.843672  -0.536858 0.000000  158.73952 
-0.000000 -0.000000 1.000000 -23.99983 
11 'point symmetry operation' ?     ?     -1.000000 -0.000000 0.000000  458.00005 0.000000  -1.000000 -0.000000 457.99988 0.000000 
-0.000000 1.000000 0.00019   
12 'point symmetry operation' ?     ?     -0.536858 0.843673  0.000000  158.73936 -0.843673 -0.536858 -0.000000 545.14170 
-0.000000 -0.000000 1.000000 24.00006  
13 'point symmetry operation' ?     ?     0.423568  0.905865  0.000000  -75.43982 -0.905865 0.423568  -0.000000 339.44594 
-0.000000 -0.000000 1.000000 48.00027  
14 'point symmetry operation' ?     ?     0.991649  0.128969  -0.000000 -27.62148 -0.128969 0.991649  -0.000000 31.44613  0.000000 
0.000000  1.000000 71.99961  
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU C 6   ? LYS C 36  ? GLU A 18  LYS A 48  1 ? 31 
HELX_P HELX_P2  AA2 SER C 38  ? ARG C 43  ? SER A 50  ARG A 55  1 ? 6  
HELX_P HELX_P3  AA3 LEU C 44  ? PHE C 59  ? LEU A 56  PHE A 71  1 ? 16 
HELX_P HELX_P4  AA4 ASP C 60  ? HIS C 70  ? ASP A 72  HIS A 82  1 ? 11 
HELX_P HELX_P5  AA5 LYS C 101 ? ASN C 112 ? LYS A 113 ASN A 124 1 ? 12 
HELX_P HELX_P6  AA6 ALA C 117 ? TYR C 136 ? ALA A 129 TYR A 148 1 ? 20 
HELX_P HELX_P7  AA7 ARG C 138 ? THR C 145 ? ARG A 150 THR A 157 1 ? 8  
HELX_P HELX_P8  AA8 MET C 151 ? MET C 155 ? MET A 163 MET A 167 5 ? 5  
HELX_P HELX_P9  AA9 GLY C 165 ? LYS C 172 ? GLY A 177 LYS A 184 1 ? 8  
HELX_P HELX_P10 AB1 GLY C 173 ? ASP C 191 ? GLY A 185 ASP A 203 1 ? 19 
HELX_P HELX_P11 AB2 GLY C 197 ? PHE C 218 ? GLY A 209 PHE A 230 1 ? 22 
HELX_P HELX_P12 AB3 THR C 220 ? SER C 233 ? THR A 232 SER A 245 1 ? 14 
HELX_P HELX_P13 AB4 GLY C 237 ? ALA C 251 ? GLY A 249 ALA A 263 1 ? 15 
HELX_P HELX_P14 AB5 PRO C 265 ? SER C 275 ? PRO A 277 SER A 287 1 ? 11 
HELX_P HELX_P15 AB6 ASP C 278 ? GLY C 283 ? ASP A 290 GLY A 295 1 ? 6  
HELX_P HELX_P16 AB7 GLY C 288 ? ASN C 297 ? GLY A 300 ASN A 309 1 ? 10 
HELX_P HELX_P17 AB8 ASN C 309 ? SER C 323 ? ASN A 321 SER A 335 1 ? 15 
HELX_P HELX_P18 AB9 ASP C 328 ? GLY C 337 ? ASP A 340 GLY A 349 1 ? 10 
HELX_P HELX_P19 AC1 PRO C 342 ? LEU C 346 ? PRO A 354 LEU A 358 5 ? 5  
HELX_P HELX_P20 AC2 SER C 426 ? ALA C 439 ? SER A 438 ALA A 451 1 ? 14 
HELX_P HELX_P21 AC3 ASP D 409 ? ALA D 415 ? ASP B 421 ALA B 427 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            covale1 
_struct_conn.conn_type_id                  covale 
_struct_conn.pdbx_leaving_atom_flag        one 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           C 
_struct_conn.ptnr1_label_seq_id            6 
_struct_conn.ptnr1_label_atom_id           "O3'" 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           E 
_struct_conn.ptnr2_label_comp_id           A1IJK 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           C1 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            C 
_struct_conn.ptnr1_auth_comp_id            C 
_struct_conn.ptnr1_auth_seq_id             12 
_struct_conn.ptnr2_auth_asym_id            C 
_struct_conn.ptnr2_auth_comp_id            A1IJK 
_struct_conn.ptnr2_auth_seq_id             101 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               1.433 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS C 79  ? VAL C 88  ? LYS A 91  VAL A 100 
AA1 2 LYS C 91  ? ASP C 100 ? LYS A 103 ASP A 112 
AA2 1 VAL C 300 ? ILE C 304 ? VAL A 312 ILE A 316 
AA2 2 GLU C 363 ? LEU C 367 ? GLU A 375 LEU A 379 
AA3 1 TYR C 373 ? TRP C 374 ? TYR A 385 TRP A 386 
AA3 2 PHE C 452 ? GLU C 453 ? PHE A 464 GLU A 465 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR C 80  ? N THR A 92  O TYR C 99  ? O TYR A 111 
AA2 1 2 N ILE C 304 ? N ILE A 316 O GLU C 363 ? O GLU A 375 
AA3 1 2 N TRP C 374 ? N TRP A 386 O PHE C 452 ? O PHE A 464 
# 
_pdbx_entry_details.entry_id                   9GAP 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            P 
_pdbx_validate_rmsd_bond.auth_asym_id_1            D 
_pdbx_validate_rmsd_bond.auth_comp_id_1            U 
_pdbx_validate_rmsd_bond.auth_seq_id_1             1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            OP3 
_pdbx_validate_rmsd_bond.auth_asym_id_2            D 
_pdbx_validate_rmsd_bond.auth_comp_id_2            U 
_pdbx_validate_rmsd_bond.auth_seq_id_2             1 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.478 
_pdbx_validate_rmsd_bond.bond_target_value         1.607 
_pdbx_validate_rmsd_bond.bond_deviation            -0.129 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.012 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLU A 18  ? ? -69.46  6.41  
2 1 ASP A 101 ? ? 35.45   42.55 
3 1 ARG A 150 ? ? -101.13 65.84 
4 1 MET A 163 ? ? -90.72  57.84 
5 1 LEU A 381 ? ? -93.30  52.62 
6 1 PRO A 453 ? ? -84.67  41.74 
7 1 PHE A 489 ? ? -95.21  53.06 
8 1 LEU B 418 ? ? 53.23   73.23 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9GAP 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9GAP 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  4.00 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               158401 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               HELICAL 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       
;20 mM HEPES
150 mM NaCl
5 mM beta-mercaptoethanol
2 mM methyl-PEG8-NHS
;
_em_buffer.pH            7.5 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 'MULTIPLE SOURCES' COMPLEX 'complex NP-RNA' ? ? ? '1, 2' 
2 1 RECOMBINANT        COMPLEX RNA              ? ? ? 1      
3 1 RECOMBINANT        COMPLEX Nucleoprotein    ? ? ? 2      
# 
_em_imaging.entry_id                        9GAP 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS GLACIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           36000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_vitrification.entry_id              9GAP 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              98 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   298 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               '5 seconds blot at force 0' 
# 
_em_experiment.entry_id                9GAP 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   HELICAL 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 C U   13  ? A U   7   
2   1 Y 1 C C   14  ? A C   8   
3   1 Y 1 C U   15  ? A U   9   
4   1 Y 1 C C   16  ? A C   10  
5   1 Y 1 C U   17  ? A U   11  
6   1 Y 1 C C   18  ? A C   12  
7   1 Y 1 D U   7   ? B U   7   
8   1 Y 1 D C   8   ? B C   8   
9   1 Y 1 D U   9   ? B U   9   
10  1 Y 1 D C   10  ? B C   10  
11  1 Y 1 D U   11  ? B U   11  
12  1 Y 1 D C   12  ? B C   12  
13  1 Y 1 A HIS 13  ? C HIS 1   
14  1 Y 1 A MET 14  ? C MET 2   
15  1 Y 1 A GLN 398 ? C GLN 386 
16  1 Y 1 A GLN 399 ? C GLN 387 
17  1 Y 1 A ARG 400 ? C ARG 388 
18  1 Y 1 A ALA 401 ? C ALA 389 
19  1 Y 1 A SER 402 ? C SER 390 
20  1 Y 1 A SER 403 ? C SER 391 
21  1 Y 1 A GLY 404 ? C GLY 392 
22  1 Y 1 A GLN 405 ? C GLN 393 
23  1 Y 1 A ILE 406 ? C ILE 394 
24  1 Y 1 A SER 407 ? C SER 395 
25  1 Y 1 A ILE 408 ? C ILE 396 
26  1 Y 1 A GLN 409 ? C GLN 397 
27  1 Y 1 A PRO 410 ? C PRO 398 
28  1 Y 1 A THR 411 ? C THR 399 
29  1 Y 1 A PHE 412 ? C PHE 400 
30  1 Y 1 A SER 413 ? C SER 401 
31  1 Y 1 A VAL 414 ? C VAL 402 
32  1 Y 1 A GLN 415 ? C GLN 403 
33  1 Y 1 A ARG 416 ? C ARG 404 
34  1 Y 1 A ASN 417 ? C ASN 405 
35  1 Y 1 A LEU 418 ? C LEU 406 
36  1 Y 1 A PRO 419 ? C PRO 407 
37  1 Y 1 A PHE 420 ? C PHE 408 
38  1 Y 1 A ASP 421 ? C ASP 409 
39  1 Y 1 A ARG 422 ? C ARG 410 
40  1 Y 1 A PRO 423 ? C PRO 411 
41  1 Y 1 A THR 424 ? C THR 412 
42  1 Y 1 A ILE 425 ? C ILE 413 
43  1 Y 1 A MET 426 ? C MET 414 
44  1 Y 1 A ALA 427 ? C ALA 415 
45  1 Y 1 A ALA 428 ? C ALA 416 
46  1 Y 1 A PHE 429 ? C PHE 417 
47  1 Y 1 A THR 430 ? C THR 418 
48  1 Y 1 A GLY 431 ? C GLY 419 
49  1 Y 1 A ASN 432 ? C ASN 420 
50  1 Y 1 A THR 433 ? C THR 421 
51  1 Y 1 A GLU 434 ? C GLU 422 
52  1 Y 1 A GLY 435 ? C GLY 423 
53  1 Y 1 A ARG 436 ? C ARG 424 
54  1 Y 1 A ASP 480 ? C ASP 468 
55  1 Y 1 A MET 481 ? C MET 469 
56  1 Y 1 A SER 482 ? C SER 470 
57  1 Y 1 A ASN 483 ? C ASN 471 
58  1 Y 1 A ASP 491 ? C ASP 479 
59  1 Y 1 A ASN 492 ? C ASN 480 
60  1 Y 1 A ALA 493 ? C ALA 481 
61  1 Y 1 A GLU 494 ? C GLU 482 
62  1 Y 1 A GLU 495 ? C GLU 483 
63  1 Y 1 A TYR 496 ? C TYR 484 
64  1 Y 1 A ASP 497 ? C ASP 485 
65  1 Y 1 A ASN 498 ? C ASN 486 
66  1 Y 1 A LEU 499 ? C LEU 487 
67  1 Y 1 A GLU 500 ? C GLU 488 
68  1 Y 1 A HIS 501 ? C HIS 489 
69  1 Y 1 A HIS 502 ? C HIS 490 
70  1 Y 1 A HIS 503 ? C HIS 491 
71  1 Y 1 A HIS 504 ? C HIS 492 
72  1 Y 1 A HIS 505 ? C HIS 493 
73  1 Y 1 A HIS 506 ? C HIS 494 
74  1 Y 1 B HIS 13  ? D HIS 1   
75  1 Y 1 B MET 14  ? D MET 2   
76  1 Y 1 B THR 15  ? D THR 3   
77  1 Y 1 B ASP 16  ? D ASP 4   
78  1 Y 1 B GLY 17  ? D GLY 5   
79  1 Y 1 B GLU 18  ? D GLU 6   
80  1 Y 1 B ARG 19  ? D ARG 7   
81  1 Y 1 B GLN 20  ? D GLN 8   
82  1 Y 1 B ASN 21  ? D ASN 9   
83  1 Y 1 B ALA 22  ? D ALA 10  
84  1 Y 1 B THR 23  ? D THR 11  
85  1 Y 1 B GLU 24  ? D GLU 12  
86  1 Y 1 B ILE 25  ? D ILE 13  
87  1 Y 1 B ARG 26  ? D ARG 14  
88  1 Y 1 B ALA 27  ? D ALA 15  
89  1 Y 1 B SER 28  ? D SER 16  
90  1 Y 1 B VAL 29  ? D VAL 17  
91  1 Y 1 B GLY 30  ? D GLY 18  
92  1 Y 1 B LYS 31  ? D LYS 19  
93  1 Y 1 B MET 32  ? D MET 20  
94  1 Y 1 B ILE 33  ? D ILE 21  
95  1 Y 1 B ASP 34  ? D ASP 22  
96  1 Y 1 B GLY 35  ? D GLY 23  
97  1 Y 1 B ILE 36  ? D ILE 24  
98  1 Y 1 B GLY 37  ? D GLY 25  
99  1 Y 1 B ARG 38  ? D ARG 26  
100 1 Y 1 B PHE 39  ? D PHE 27  
101 1 Y 1 B TYR 40  ? D TYR 28  
102 1 Y 1 B ILE 41  ? D ILE 29  
103 1 Y 1 B GLN 42  ? D GLN 30  
104 1 Y 1 B MET 43  ? D MET 31  
105 1 Y 1 B CYS 44  ? D CYS 32  
106 1 Y 1 B THR 45  ? D THR 33  
107 1 Y 1 B GLU 46  ? D GLU 34  
108 1 Y 1 B LEU 47  ? D LEU 35  
109 1 Y 1 B LYS 48  ? D LYS 36  
110 1 Y 1 B LEU 49  ? D LEU 37  
111 1 Y 1 B SER 50  ? D SER 38  
112 1 Y 1 B ASP 51  ? D ASP 39  
113 1 Y 1 B TYR 52  ? D TYR 40  
114 1 Y 1 B GLU 53  ? D GLU 41  
115 1 Y 1 B GLY 54  ? D GLY 42  
116 1 Y 1 B ARG 55  ? D ARG 43  
117 1 Y 1 B LEU 56  ? D LEU 44  
118 1 Y 1 B ILE 57  ? D ILE 45  
119 1 Y 1 B GLN 58  ? D GLN 46  
120 1 Y 1 B ASN 59  ? D ASN 47  
121 1 Y 1 B SER 60  ? D SER 48  
122 1 Y 1 B LEU 61  ? D LEU 49  
123 1 Y 1 B THR 62  ? D THR 50  
124 1 Y 1 B ILE 63  ? D ILE 51  
125 1 Y 1 B GLU 64  ? D GLU 52  
126 1 Y 1 B ARG 65  ? D ARG 53  
127 1 Y 1 B MET 66  ? D MET 54  
128 1 Y 1 B VAL 67  ? D VAL 55  
129 1 Y 1 B LEU 68  ? D LEU 56  
130 1 Y 1 B SER 69  ? D SER 57  
131 1 Y 1 B ALA 70  ? D ALA 58  
132 1 Y 1 B PHE 71  ? D PHE 59  
133 1 Y 1 B ASP 72  ? D ASP 60  
134 1 Y 1 B GLU 73  ? D GLU 61  
135 1 Y 1 B ARG 74  ? D ARG 62  
136 1 Y 1 B ARG 75  ? D ARG 63  
137 1 Y 1 B ASN 76  ? D ASN 64  
138 1 Y 1 B LYS 77  ? D LYS 65  
139 1 Y 1 B TYR 78  ? D TYR 66  
140 1 Y 1 B LEU 79  ? D LEU 67  
141 1 Y 1 B GLU 80  ? D GLU 68  
142 1 Y 1 B GLU 81  ? D GLU 69  
143 1 Y 1 B HIS 82  ? D HIS 70  
144 1 Y 1 B PRO 83  ? D PRO 71  
145 1 Y 1 B SER 84  ? D SER 72  
146 1 Y 1 B ALA 85  ? D ALA 73  
147 1 Y 1 B GLY 86  ? D GLY 74  
148 1 Y 1 B LYS 87  ? D LYS 75  
149 1 Y 1 B ASP 88  ? D ASP 76  
150 1 Y 1 B PRO 89  ? D PRO 77  
151 1 Y 1 B LYS 90  ? D LYS 78  
152 1 Y 1 B LYS 91  ? D LYS 79  
153 1 Y 1 B THR 92  ? D THR 80  
154 1 Y 1 B GLY 93  ? D GLY 81  
155 1 Y 1 B GLY 94  ? D GLY 82  
156 1 Y 1 B PRO 95  ? D PRO 83  
157 1 Y 1 B ILE 96  ? D ILE 84  
158 1 Y 1 B TYR 97  ? D TYR 85  
159 1 Y 1 B ARG 98  ? D ARG 86  
160 1 Y 1 B ARG 99  ? D ARG 87  
161 1 Y 1 B VAL 100 ? D VAL 88  
162 1 Y 1 B ASP 101 ? D ASP 89  
163 1 Y 1 B GLY 102 ? D GLY 90  
164 1 Y 1 B LYS 103 ? D LYS 91  
165 1 Y 1 B TRP 104 ? D TRP 92  
166 1 Y 1 B ARG 105 ? D ARG 93  
167 1 Y 1 B ARG 106 ? D ARG 94  
168 1 Y 1 B GLU 107 ? D GLU 95  
169 1 Y 1 B LEU 108 ? D LEU 96  
170 1 Y 1 B ILE 109 ? D ILE 97  
171 1 Y 1 B LEU 110 ? D LEU 98  
172 1 Y 1 B TYR 111 ? D TYR 99  
173 1 Y 1 B ASP 112 ? D ASP 100 
174 1 Y 1 B LYS 113 ? D LYS 101 
175 1 Y 1 B GLU 114 ? D GLU 102 
176 1 Y 1 B GLU 115 ? D GLU 103 
177 1 Y 1 B ILE 116 ? D ILE 104 
178 1 Y 1 B ARG 117 ? D ARG 105 
179 1 Y 1 B ARG 118 ? D ARG 106 
180 1 Y 1 B ILE 119 ? D ILE 107 
181 1 Y 1 B TRP 120 ? D TRP 108 
182 1 Y 1 B ARG 121 ? D ARG 109 
183 1 Y 1 B GLN 122 ? D GLN 110 
184 1 Y 1 B ALA 123 ? D ALA 111 
185 1 Y 1 B ASN 124 ? D ASN 112 
186 1 Y 1 B ASN 125 ? D ASN 113 
187 1 Y 1 B GLY 126 ? D GLY 114 
188 1 Y 1 B ASP 127 ? D ASP 115 
189 1 Y 1 B ASP 128 ? D ASP 116 
190 1 Y 1 B ALA 129 ? D ALA 117 
191 1 Y 1 B THR 130 ? D THR 118 
192 1 Y 1 B ALA 131 ? D ALA 119 
193 1 Y 1 B GLY 132 ? D GLY 120 
194 1 Y 1 B LEU 133 ? D LEU 121 
195 1 Y 1 B THR 134 ? D THR 122 
196 1 Y 1 B HIS 135 ? D HIS 123 
197 1 Y 1 B MET 136 ? D MET 124 
198 1 Y 1 B MET 137 ? D MET 125 
199 1 Y 1 B ILE 138 ? D ILE 126 
200 1 Y 1 B TRP 139 ? D TRP 127 
201 1 Y 1 B HIS 140 ? D HIS 128 
202 1 Y 1 B SER 141 ? D SER 129 
203 1 Y 1 B ASN 142 ? D ASN 130 
204 1 Y 1 B LEU 143 ? D LEU 131 
205 1 Y 1 B ASN 144 ? D ASN 132 
206 1 Y 1 B ASP 145 ? D ASP 133 
207 1 Y 1 B ALA 146 ? D ALA 134 
208 1 Y 1 B THR 147 ? D THR 135 
209 1 Y 1 B TYR 148 ? D TYR 136 
210 1 Y 1 B GLN 149 ? D GLN 137 
211 1 Y 1 B ARG 150 ? D ARG 138 
212 1 Y 1 B THR 151 ? D THR 139 
213 1 Y 1 B ARG 152 ? D ARG 140 
214 1 Y 1 B ALA 153 ? D ALA 141 
215 1 Y 1 B LEU 154 ? D LEU 142 
216 1 Y 1 B VAL 155 ? D VAL 143 
217 1 Y 1 B ARG 156 ? D ARG 144 
218 1 Y 1 B THR 157 ? D THR 145 
219 1 Y 1 B GLY 158 ? D GLY 146 
220 1 Y 1 B MET 159 ? D MET 147 
221 1 Y 1 B ASP 160 ? D ASP 148 
222 1 Y 1 B PRO 161 ? D PRO 149 
223 1 Y 1 B ARG 162 ? D ARG 150 
224 1 Y 1 B MET 163 ? D MET 151 
225 1 Y 1 B CYS 164 ? D CYS 152 
226 1 Y 1 B SER 165 ? D SER 153 
227 1 Y 1 B LEU 166 ? D LEU 154 
228 1 Y 1 B MET 167 ? D MET 155 
229 1 Y 1 B GLN 168 ? D GLN 156 
230 1 Y 1 B GLY 169 ? D GLY 157 
231 1 Y 1 B SER 170 ? D SER 158 
232 1 Y 1 B THR 171 ? D THR 159 
233 1 Y 1 B LEU 172 ? D LEU 160 
234 1 Y 1 B PRO 173 ? D PRO 161 
235 1 Y 1 B ARG 174 ? D ARG 162 
236 1 Y 1 B ARG 175 ? D ARG 163 
237 1 Y 1 B SER 176 ? D SER 164 
238 1 Y 1 B GLY 177 ? D GLY 165 
239 1 Y 1 B ALA 178 ? D ALA 166 
240 1 Y 1 B ALA 179 ? D ALA 167 
241 1 Y 1 B GLY 180 ? D GLY 168 
242 1 Y 1 B ALA 181 ? D ALA 169 
243 1 Y 1 B ALA 182 ? D ALA 170 
244 1 Y 1 B VAL 183 ? D VAL 171 
245 1 Y 1 B LYS 184 ? D LYS 172 
246 1 Y 1 B GLY 185 ? D GLY 173 
247 1 Y 1 B VAL 186 ? D VAL 174 
248 1 Y 1 B GLY 187 ? D GLY 175 
249 1 Y 1 B THR 188 ? D THR 176 
250 1 Y 1 B MET 189 ? D MET 177 
251 1 Y 1 B VAL 190 ? D VAL 178 
252 1 Y 1 B MET 191 ? D MET 179 
253 1 Y 1 B GLU 192 ? D GLU 180 
254 1 Y 1 B LEU 193 ? D LEU 181 
255 1 Y 1 B ILE 194 ? D ILE 182 
256 1 Y 1 B ARG 195 ? D ARG 183 
257 1 Y 1 B MET 196 ? D MET 184 
258 1 Y 1 B ILE 197 ? D ILE 185 
259 1 Y 1 B LYS 198 ? D LYS 186 
260 1 Y 1 B ARG 199 ? D ARG 187 
261 1 Y 1 B GLY 200 ? D GLY 188 
262 1 Y 1 B ILE 201 ? D ILE 189 
263 1 Y 1 B ASN 202 ? D ASN 190 
264 1 Y 1 B ASP 203 ? D ASP 191 
265 1 Y 1 B ARG 204 ? D ARG 192 
266 1 Y 1 B ASN 205 ? D ASN 193 
267 1 Y 1 B PHE 206 ? D PHE 194 
268 1 Y 1 B TRP 207 ? D TRP 195 
269 1 Y 1 B ARG 208 ? D ARG 196 
270 1 Y 1 B GLY 209 ? D GLY 197 
271 1 Y 1 B GLU 210 ? D GLU 198 
272 1 Y 1 B ASN 211 ? D ASN 199 
273 1 Y 1 B GLY 212 ? D GLY 200 
274 1 Y 1 B ARG 213 ? D ARG 201 
275 1 Y 1 B ARG 214 ? D ARG 202 
276 1 Y 1 B THR 215 ? D THR 203 
277 1 Y 1 B ARG 216 ? D ARG 204 
278 1 Y 1 B ILE 217 ? D ILE 205 
279 1 Y 1 B ALA 218 ? D ALA 206 
280 1 Y 1 B TYR 219 ? D TYR 207 
281 1 Y 1 B GLU 220 ? D GLU 208 
282 1 Y 1 B ARG 221 ? D ARG 209 
283 1 Y 1 B MET 222 ? D MET 210 
284 1 Y 1 B CYS 223 ? D CYS 211 
285 1 Y 1 B ASN 224 ? D ASN 212 
286 1 Y 1 B ILE 225 ? D ILE 213 
287 1 Y 1 B LEU 226 ? D LEU 214 
288 1 Y 1 B LYS 227 ? D LYS 215 
289 1 Y 1 B GLY 228 ? D GLY 216 
290 1 Y 1 B LYS 229 ? D LYS 217 
291 1 Y 1 B PHE 230 ? D PHE 218 
292 1 Y 1 B GLN 231 ? D GLN 219 
293 1 Y 1 B THR 232 ? D THR 220 
294 1 Y 1 B ALA 233 ? D ALA 221 
295 1 Y 1 B ALA 234 ? D ALA 222 
296 1 Y 1 B GLN 235 ? D GLN 223 
297 1 Y 1 B ARG 236 ? D ARG 224 
298 1 Y 1 B THR 237 ? D THR 225 
299 1 Y 1 B MET 238 ? D MET 226 
300 1 Y 1 B VAL 239 ? D VAL 227 
301 1 Y 1 B ASP 240 ? D ASP 228 
302 1 Y 1 B GLN 241 ? D GLN 229 
303 1 Y 1 B VAL 242 ? D VAL 230 
304 1 Y 1 B ARG 243 ? D ARG 231 
305 1 Y 1 B GLU 244 ? D GLU 232 
306 1 Y 1 B SER 245 ? D SER 233 
307 1 Y 1 B ARG 246 ? D ARG 234 
308 1 Y 1 B ASN 247 ? D ASN 235 
309 1 Y 1 B PRO 248 ? D PRO 236 
310 1 Y 1 B GLY 249 ? D GLY 237 
311 1 Y 1 B ASN 250 ? D ASN 238 
312 1 Y 1 B ALA 251 ? D ALA 239 
313 1 Y 1 B GLU 252 ? D GLU 240 
314 1 Y 1 B PHE 253 ? D PHE 241 
315 1 Y 1 B GLU 254 ? D GLU 242 
316 1 Y 1 B ASP 255 ? D ASP 243 
317 1 Y 1 B LEU 256 ? D LEU 244 
318 1 Y 1 B ILE 257 ? D ILE 245 
319 1 Y 1 B PHE 258 ? D PHE 246 
320 1 Y 1 B LEU 259 ? D LEU 247 
321 1 Y 1 B ALA 260 ? D ALA 248 
322 1 Y 1 B ARG 261 ? D ARG 249 
323 1 Y 1 B SER 262 ? D SER 250 
324 1 Y 1 B ALA 263 ? D ALA 251 
325 1 Y 1 B LEU 264 ? D LEU 252 
326 1 Y 1 B ILE 265 ? D ILE 253 
327 1 Y 1 B LEU 266 ? D LEU 254 
328 1 Y 1 B ARG 267 ? D ARG 255 
329 1 Y 1 B GLY 268 ? D GLY 256 
330 1 Y 1 B SER 269 ? D SER 257 
331 1 Y 1 B VAL 270 ? D VAL 258 
332 1 Y 1 B ALA 271 ? D ALA 259 
333 1 Y 1 B HIS 272 ? D HIS 260 
334 1 Y 1 B LYS 273 ? D LYS 261 
335 1 Y 1 B SER 274 ? D SER 262 
336 1 Y 1 B CYS 275 ? D CYS 263 
337 1 Y 1 B LEU 276 ? D LEU 264 
338 1 Y 1 B PRO 277 ? D PRO 265 
339 1 Y 1 B ALA 278 ? D ALA 266 
340 1 Y 1 B CYS 279 ? D CYS 267 
341 1 Y 1 B VAL 280 ? D VAL 268 
342 1 Y 1 B TYR 281 ? D TYR 269 
343 1 Y 1 B GLY 282 ? D GLY 270 
344 1 Y 1 B SER 283 ? D SER 271 
345 1 Y 1 B ALA 284 ? D ALA 272 
346 1 Y 1 B VAL 285 ? D VAL 273 
347 1 Y 1 B ALA 286 ? D ALA 274 
348 1 Y 1 B SER 287 ? D SER 275 
349 1 Y 1 B GLY 288 ? D GLY 276 
350 1 Y 1 B TYR 289 ? D TYR 277 
351 1 Y 1 B ASP 290 ? D ASP 278 
352 1 Y 1 B PHE 291 ? D PHE 279 
353 1 Y 1 B GLU 292 ? D GLU 280 
354 1 Y 1 B ARG 293 ? D ARG 281 
355 1 Y 1 B GLU 294 ? D GLU 282 
356 1 Y 1 B GLY 295 ? D GLY 283 
357 1 Y 1 B TYR 296 ? D TYR 284 
358 1 Y 1 B SER 297 ? D SER 285 
359 1 Y 1 B LEU 298 ? D LEU 286 
360 1 Y 1 B VAL 299 ? D VAL 287 
361 1 Y 1 B GLY 300 ? D GLY 288 
362 1 Y 1 B ILE 301 ? D ILE 289 
363 1 Y 1 B ASP 302 ? D ASP 290 
364 1 Y 1 B PRO 303 ? D PRO 291 
365 1 Y 1 B PHE 304 ? D PHE 292 
366 1 Y 1 B ARG 305 ? D ARG 293 
367 1 Y 1 B LEU 306 ? D LEU 294 
368 1 Y 1 B LEU 307 ? D LEU 295 
369 1 Y 1 B GLN 308 ? D GLN 296 
370 1 Y 1 B ASN 309 ? D ASN 297 
371 1 Y 1 B SER 310 ? D SER 298 
372 1 Y 1 B GLN 311 ? D GLN 299 
373 1 Y 1 B VAL 312 ? D VAL 300 
374 1 Y 1 B TYR 313 ? D TYR 301 
375 1 Y 1 B SER 314 ? D SER 302 
376 1 Y 1 B LEU 315 ? D LEU 303 
377 1 Y 1 B ILE 316 ? D ILE 304 
378 1 Y 1 B ARG 317 ? D ARG 305 
379 1 Y 1 B PRO 318 ? D PRO 306 
380 1 Y 1 B ASN 319 ? D ASN 307 
381 1 Y 1 B GLU 320 ? D GLU 308 
382 1 Y 1 B ASN 321 ? D ASN 309 
383 1 Y 1 B PRO 322 ? D PRO 310 
384 1 Y 1 B ALA 323 ? D ALA 311 
385 1 Y 1 B HIS 324 ? D HIS 312 
386 1 Y 1 B LYS 325 ? D LYS 313 
387 1 Y 1 B SER 326 ? D SER 314 
388 1 Y 1 B GLN 327 ? D GLN 315 
389 1 Y 1 B LEU 328 ? D LEU 316 
390 1 Y 1 B VAL 329 ? D VAL 317 
391 1 Y 1 B TRP 330 ? D TRP 318 
392 1 Y 1 B MET 331 ? D MET 319 
393 1 Y 1 B ALA 332 ? D ALA 320 
394 1 Y 1 B CYS 333 ? D CYS 321 
395 1 Y 1 B HIS 334 ? D HIS 322 
396 1 Y 1 B SER 335 ? D SER 323 
397 1 Y 1 B ALA 336 ? D ALA 324 
398 1 Y 1 B ALA 337 ? D ALA 325 
399 1 Y 1 B PHE 338 ? D PHE 326 
400 1 Y 1 B GLU 339 ? D GLU 327 
401 1 Y 1 B ASP 340 ? D ASP 328 
402 1 Y 1 B LEU 341 ? D LEU 329 
403 1 Y 1 B ARG 342 ? D ARG 330 
404 1 Y 1 B VAL 343 ? D VAL 331 
405 1 Y 1 B SER 344 ? D SER 332 
406 1 Y 1 B SER 345 ? D SER 333 
407 1 Y 1 B PHE 346 ? D PHE 334 
408 1 Y 1 B ILE 347 ? D ILE 335 
409 1 Y 1 B ARG 348 ? D ARG 336 
410 1 Y 1 B GLY 349 ? D GLY 337 
411 1 Y 1 B THR 350 ? D THR 338 
412 1 Y 1 B LYS 351 ? D LYS 339 
413 1 Y 1 B VAL 352 ? D VAL 340 
414 1 Y 1 B VAL 353 ? D VAL 341 
415 1 Y 1 B PRO 354 ? D PRO 342 
416 1 Y 1 B ARG 355 ? D ARG 343 
417 1 Y 1 B GLY 356 ? D GLY 344 
418 1 Y 1 B LYS 357 ? D LYS 345 
419 1 Y 1 B LEU 358 ? D LEU 346 
420 1 Y 1 B SER 359 ? D SER 347 
421 1 Y 1 B THR 360 ? D THR 348 
422 1 Y 1 B ARG 361 ? D ARG 349 
423 1 Y 1 B GLY 362 ? D GLY 350 
424 1 Y 1 B VAL 363 ? D VAL 351 
425 1 Y 1 B GLN 364 ? D GLN 352 
426 1 Y 1 B ILE 365 ? D ILE 353 
427 1 Y 1 B ALA 366 ? D ALA 354 
428 1 Y 1 B SER 367 ? D SER 355 
429 1 Y 1 B ASN 368 ? D ASN 356 
430 1 Y 1 B GLU 369 ? D GLU 357 
431 1 Y 1 B ASN 370 ? D ASN 358 
432 1 Y 1 B MET 371 ? D MET 359 
433 1 Y 1 B GLU 372 ? D GLU 360 
434 1 Y 1 B THR 373 ? D THR 361 
435 1 Y 1 B MET 374 ? D MET 362 
436 1 Y 1 B GLU 375 ? D GLU 363 
437 1 Y 1 B SER 376 ? D SER 364 
438 1 Y 1 B SER 377 ? D SER 365 
439 1 Y 1 B THR 378 ? D THR 366 
440 1 Y 1 B LEU 379 ? D LEU 367 
441 1 Y 1 B GLU 380 ? D GLU 368 
442 1 Y 1 B LEU 381 ? D LEU 369 
443 1 Y 1 B ARG 382 ? D ARG 370 
444 1 Y 1 B SER 383 ? D SER 371 
445 1 Y 1 B ARG 384 ? D ARG 372 
446 1 Y 1 B TYR 385 ? D TYR 373 
447 1 Y 1 B TRP 386 ? D TRP 374 
448 1 Y 1 B ALA 387 ? D ALA 375 
449 1 Y 1 B ILE 388 ? D ILE 376 
450 1 Y 1 B ARG 389 ? D ARG 377 
451 1 Y 1 B THR 390 ? D THR 378 
452 1 Y 1 B ARG 391 ? D ARG 379 
453 1 Y 1 B SER 392 ? D SER 380 
454 1 Y 1 B GLY 393 ? D GLY 381 
455 1 Y 1 B GLY 394 ? D GLY 382 
456 1 Y 1 B ASN 395 ? D ASN 383 
457 1 Y 1 B THR 396 ? D THR 384 
458 1 Y 1 B ASN 397 ? D ASN 385 
459 1 Y 1 B GLN 398 ? D GLN 386 
460 1 Y 1 B GLN 399 ? D GLN 387 
461 1 Y 1 B ARG 400 ? D ARG 388 
462 1 Y 1 B ALA 401 ? D ALA 389 
463 1 Y 1 B THR 430 ? D THR 418 
464 1 Y 1 B GLY 431 ? D GLY 419 
465 1 Y 1 B ASN 432 ? D ASN 420 
466 1 Y 1 B THR 433 ? D THR 421 
467 1 Y 1 B GLU 434 ? D GLU 422 
468 1 Y 1 B GLY 435 ? D GLY 423 
469 1 Y 1 B ARG 436 ? D ARG 424 
470 1 Y 1 B THR 437 ? D THR 425 
471 1 Y 1 B SER 438 ? D SER 426 
472 1 Y 1 B ASP 439 ? D ASP 427 
473 1 Y 1 B MET 440 ? D MET 428 
474 1 Y 1 B ARG 441 ? D ARG 429 
475 1 Y 1 B THR 442 ? D THR 430 
476 1 Y 1 B GLU 443 ? D GLU 431 
477 1 Y 1 B ILE 444 ? D ILE 432 
478 1 Y 1 B ILE 445 ? D ILE 433 
479 1 Y 1 B ARG 446 ? D ARG 434 
480 1 Y 1 B LEU 447 ? D LEU 435 
481 1 Y 1 B MET 448 ? D MET 436 
482 1 Y 1 B GLU 449 ? D GLU 437 
483 1 Y 1 B SER 450 ? D SER 438 
484 1 Y 1 B ALA 451 ? D ALA 439 
485 1 Y 1 B ARG 452 ? D ARG 440 
486 1 Y 1 B PRO 453 ? D PRO 441 
487 1 Y 1 B GLU 454 ? D GLU 442 
488 1 Y 1 B ASP 455 ? D ASP 443 
489 1 Y 1 B VAL 456 ? D VAL 444 
490 1 Y 1 B SER 457 ? D SER 445 
491 1 Y 1 B PHE 458 ? D PHE 446 
492 1 Y 1 B GLN 459 ? D GLN 447 
493 1 Y 1 B GLY 460 ? D GLY 448 
494 1 Y 1 B ARG 461 ? D ARG 449 
495 1 Y 1 B GLY 462 ? D GLY 450 
496 1 Y 1 B VAL 463 ? D VAL 451 
497 1 Y 1 B PHE 464 ? D PHE 452 
498 1 Y 1 B GLU 465 ? D GLU 453 
499 1 Y 1 B LEU 466 ? D LEU 454 
500 1 Y 1 B SER 467 ? D SER 455 
501 1 Y 1 B ASP 468 ? D ASP 456 
502 1 Y 1 B GLU 469 ? D GLU 457 
503 1 Y 1 B LYS 470 ? D LYS 458 
504 1 Y 1 B ALA 471 ? D ALA 459 
505 1 Y 1 B THR 472 ? D THR 460 
506 1 Y 1 B SER 473 ? D SER 461 
507 1 Y 1 B PRO 474 ? D PRO 462 
508 1 Y 1 B ILE 475 ? D ILE 463 
509 1 Y 1 B VAL 476 ? D VAL 464 
510 1 Y 1 B PRO 477 ? D PRO 465 
511 1 Y 1 B SER 478 ? D SER 466 
512 1 Y 1 B PHE 479 ? D PHE 467 
513 1 Y 1 B ASP 480 ? D ASP 468 
514 1 Y 1 B MET 481 ? D MET 469 
515 1 Y 1 B SER 482 ? D SER 470 
516 1 Y 1 B ASN 483 ? D ASN 471 
517 1 Y 1 B GLU 484 ? D GLU 472 
518 1 Y 1 B GLY 485 ? D GLY 473 
519 1 Y 1 B SER 486 ? D SER 474 
520 1 Y 1 B TYR 487 ? D TYR 475 
521 1 Y 1 B PHE 488 ? D PHE 476 
522 1 Y 1 B PHE 489 ? D PHE 477 
523 1 Y 1 B GLY 490 ? D GLY 478 
524 1 Y 1 B ASP 491 ? D ASP 479 
525 1 Y 1 B ASN 492 ? D ASN 480 
526 1 Y 1 B ALA 493 ? D ALA 481 
527 1 Y 1 B GLU 494 ? D GLU 482 
528 1 Y 1 B GLU 495 ? D GLU 483 
529 1 Y 1 B TYR 496 ? D TYR 484 
530 1 Y 1 B ASP 497 ? D ASP 485 
531 1 Y 1 B ASN 498 ? D ASN 486 
532 1 Y 1 B LEU 499 ? D LEU 487 
533 1 Y 1 B GLU 500 ? D GLU 488 
534 1 Y 1 B HIS 501 ? D HIS 489 
535 1 Y 1 B HIS 502 ? D HIS 490 
536 1 Y 1 B HIS 503 ? D HIS 491 
537 1 Y 1 B HIS 504 ? D HIS 492 
538 1 Y 1 B HIS 505 ? D HIS 493 
539 1 Y 1 B HIS 506 ? D HIS 494 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1IJK C1     C N N 1   
A1IJK C2     C N R 2   
A1IJK C3     C N N 3   
A1IJK C6     C N N 4   
A1IJK C7     C N N 5   
A1IJK O4     O N N 6   
A1IJK O5     O N N 7   
A1IJK C8     C N N 8   
A1IJK C10    C N N 9   
A1IJK N9     N N N 10  
A1IJK C33    C N N 11  
A1IJK C34    C N N 12  
A1IJK C11    C Y N 13  
A1IJK C12    C Y N 14  
A1IJK C13    C Y N 15  
A1IJK C14    C Y N 16  
A1IJK C15    C Y N 17  
A1IJK C16    C Y N 18  
A1IJK C17    C N N 19  
A1IJK C20    C Y N 20  
A1IJK C21    C Y N 21  
A1IJK C22    C Y N 22  
A1IJK C24    C Y N 23  
A1IJK C25    C Y N 24  
A1IJK C27    C N N 25  
A1IJK C28    C N N 26  
A1IJK C29    C N N 27  
A1IJK C30    C N N 28  
A1IJK C31    C N N 29  
A1IJK C32    C N N 30  
A1IJK O18    O N N 31  
A1IJK O19    O N N 32  
A1IJK O23    O Y N 33  
A1IJK O26    O N N 34  
A1IJK O35    O N N 35  
A1IJK O36    O N N 36  
A1IJK H1     H N N 37  
A1IJK H2     H N N 38  
A1IJK H3     H N N 39  
A1IJK H4     H N N 40  
A1IJK H5     H N N 41  
A1IJK H6     H N N 42  
A1IJK H7     H N N 43  
A1IJK H8     H N N 44  
A1IJK H9     H N N 45  
A1IJK H10    H N N 46  
A1IJK H11    H N N 47  
A1IJK H12    H N N 48  
A1IJK H13    H N N 49  
A1IJK H14    H N N 50  
A1IJK H15    H N N 51  
A1IJK H16    H N N 52  
A1IJK H17    H N N 53  
A1IJK H18    H N N 54  
A1IJK H19    H N N 55  
A1IJK H20    H N N 56  
A1IJK H21    H N N 57  
A1IJK H22    H N N 58  
A1IJK H23    H N N 59  
A1IJK H24    H N N 60  
A1IJK H25    H N N 61  
A1IJK H26    H N N 62  
A1IJK H27    H N N 63  
ALA   N      N N N 64  
ALA   CA     C N S 65  
ALA   C      C N N 66  
ALA   O      O N N 67  
ALA   CB     C N N 68  
ALA   OXT    O N N 69  
ALA   H      H N N 70  
ALA   H2     H N N 71  
ALA   HA     H N N 72  
ALA   HB1    H N N 73  
ALA   HB2    H N N 74  
ALA   HB3    H N N 75  
ALA   HXT    H N N 76  
ARG   N      N N N 77  
ARG   CA     C N S 78  
ARG   C      C N N 79  
ARG   O      O N N 80  
ARG   CB     C N N 81  
ARG   CG     C N N 82  
ARG   CD     C N N 83  
ARG   NE     N N N 84  
ARG   CZ     C N N 85  
ARG   NH1    N N N 86  
ARG   NH2    N N N 87  
ARG   OXT    O N N 88  
ARG   H      H N N 89  
ARG   H2     H N N 90  
ARG   HA     H N N 91  
ARG   HB2    H N N 92  
ARG   HB3    H N N 93  
ARG   HG2    H N N 94  
ARG   HG3    H N N 95  
ARG   HD2    H N N 96  
ARG   HD3    H N N 97  
ARG   HE     H N N 98  
ARG   HH11   H N N 99  
ARG   HH12   H N N 100 
ARG   HH21   H N N 101 
ARG   HH22   H N N 102 
ARG   HXT    H N N 103 
ASN   N      N N N 104 
ASN   CA     C N S 105 
ASN   C      C N N 106 
ASN   O      O N N 107 
ASN   CB     C N N 108 
ASN   CG     C N N 109 
ASN   OD1    O N N 110 
ASN   ND2    N N N 111 
ASN   OXT    O N N 112 
ASN   H      H N N 113 
ASN   H2     H N N 114 
ASN   HA     H N N 115 
ASN   HB2    H N N 116 
ASN   HB3    H N N 117 
ASN   HD21   H N N 118 
ASN   HD22   H N N 119 
ASN   HXT    H N N 120 
ASP   N      N N N 121 
ASP   CA     C N S 122 
ASP   C      C N N 123 
ASP   O      O N N 124 
ASP   CB     C N N 125 
ASP   CG     C N N 126 
ASP   OD1    O N N 127 
ASP   OD2    O N N 128 
ASP   OXT    O N N 129 
ASP   H      H N N 130 
ASP   H2     H N N 131 
ASP   HA     H N N 132 
ASP   HB2    H N N 133 
ASP   HB3    H N N 134 
ASP   HD2    H N N 135 
ASP   HXT    H N N 136 
C     OP3    O N N 137 
C     P      P N N 138 
C     OP1    O N N 139 
C     OP2    O N N 140 
C     "O5'"  O N N 141 
C     "C5'"  C N N 142 
C     "C4'"  C N R 143 
C     "O4'"  O N N 144 
C     "C3'"  C N S 145 
C     "O3'"  O N N 146 
C     "C2'"  C N R 147 
C     "O2'"  O N N 148 
C     "C1'"  C N R 149 
C     N1     N N N 150 
C     C2     C N N 151 
C     O2     O N N 152 
C     N3     N N N 153 
C     C4     C N N 154 
C     N4     N N N 155 
C     C5     C N N 156 
C     C6     C N N 157 
C     HOP3   H N N 158 
C     HOP2   H N N 159 
C     "H5'"  H N N 160 
C     "H5''" H N N 161 
C     "H4'"  H N N 162 
C     "H3'"  H N N 163 
C     "HO3'" H N N 164 
C     "H2'"  H N N 165 
C     "HO2'" H N N 166 
C     "H1'"  H N N 167 
C     H41    H N N 168 
C     H42    H N N 169 
C     H5     H N N 170 
C     H6     H N N 171 
CYS   N      N N N 172 
CYS   CA     C N R 173 
CYS   C      C N N 174 
CYS   O      O N N 175 
CYS   CB     C N N 176 
CYS   SG     S N N 177 
CYS   OXT    O N N 178 
CYS   H      H N N 179 
CYS   H2     H N N 180 
CYS   HA     H N N 181 
CYS   HB2    H N N 182 
CYS   HB3    H N N 183 
CYS   HG     H N N 184 
CYS   HXT    H N N 185 
GLN   N      N N N 186 
GLN   CA     C N S 187 
GLN   C      C N N 188 
GLN   O      O N N 189 
GLN   CB     C N N 190 
GLN   CG     C N N 191 
GLN   CD     C N N 192 
GLN   OE1    O N N 193 
GLN   NE2    N N N 194 
GLN   OXT    O N N 195 
GLN   H      H N N 196 
GLN   H2     H N N 197 
GLN   HA     H N N 198 
GLN   HB2    H N N 199 
GLN   HB3    H N N 200 
GLN   HG2    H N N 201 
GLN   HG3    H N N 202 
GLN   HE21   H N N 203 
GLN   HE22   H N N 204 
GLN   HXT    H N N 205 
GLU   N      N N N 206 
GLU   CA     C N S 207 
GLU   C      C N N 208 
GLU   O      O N N 209 
GLU   CB     C N N 210 
GLU   CG     C N N 211 
GLU   CD     C N N 212 
GLU   OE1    O N N 213 
GLU   OE2    O N N 214 
GLU   OXT    O N N 215 
GLU   H      H N N 216 
GLU   H2     H N N 217 
GLU   HA     H N N 218 
GLU   HB2    H N N 219 
GLU   HB3    H N N 220 
GLU   HG2    H N N 221 
GLU   HG3    H N N 222 
GLU   HE2    H N N 223 
GLU   HXT    H N N 224 
GLY   N      N N N 225 
GLY   CA     C N N 226 
GLY   C      C N N 227 
GLY   O      O N N 228 
GLY   OXT    O N N 229 
GLY   H      H N N 230 
GLY   H2     H N N 231 
GLY   HA2    H N N 232 
GLY   HA3    H N N 233 
GLY   HXT    H N N 234 
HIS   N      N N N 235 
HIS   CA     C N S 236 
HIS   C      C N N 237 
HIS   O      O N N 238 
HIS   CB     C N N 239 
HIS   CG     C Y N 240 
HIS   ND1    N Y N 241 
HIS   CD2    C Y N 242 
HIS   CE1    C Y N 243 
HIS   NE2    N Y N 244 
HIS   OXT    O N N 245 
HIS   H      H N N 246 
HIS   H2     H N N 247 
HIS   HA     H N N 248 
HIS   HB2    H N N 249 
HIS   HB3    H N N 250 
HIS   HD1    H N N 251 
HIS   HD2    H N N 252 
HIS   HE1    H N N 253 
HIS   HE2    H N N 254 
HIS   HXT    H N N 255 
ILE   N      N N N 256 
ILE   CA     C N S 257 
ILE   C      C N N 258 
ILE   O      O N N 259 
ILE   CB     C N S 260 
ILE   CG1    C N N 261 
ILE   CG2    C N N 262 
ILE   CD1    C N N 263 
ILE   OXT    O N N 264 
ILE   H      H N N 265 
ILE   H2     H N N 266 
ILE   HA     H N N 267 
ILE   HB     H N N 268 
ILE   HG12   H N N 269 
ILE   HG13   H N N 270 
ILE   HG21   H N N 271 
ILE   HG22   H N N 272 
ILE   HG23   H N N 273 
ILE   HD11   H N N 274 
ILE   HD12   H N N 275 
ILE   HD13   H N N 276 
ILE   HXT    H N N 277 
LEU   N      N N N 278 
LEU   CA     C N S 279 
LEU   C      C N N 280 
LEU   O      O N N 281 
LEU   CB     C N N 282 
LEU   CG     C N N 283 
LEU   CD1    C N N 284 
LEU   CD2    C N N 285 
LEU   OXT    O N N 286 
LEU   H      H N N 287 
LEU   H2     H N N 288 
LEU   HA     H N N 289 
LEU   HB2    H N N 290 
LEU   HB3    H N N 291 
LEU   HG     H N N 292 
LEU   HD11   H N N 293 
LEU   HD12   H N N 294 
LEU   HD13   H N N 295 
LEU   HD21   H N N 296 
LEU   HD22   H N N 297 
LEU   HD23   H N N 298 
LEU   HXT    H N N 299 
LYS   N      N N N 300 
LYS   CA     C N S 301 
LYS   C      C N N 302 
LYS   O      O N N 303 
LYS   CB     C N N 304 
LYS   CG     C N N 305 
LYS   CD     C N N 306 
LYS   CE     C N N 307 
LYS   NZ     N N N 308 
LYS   OXT    O N N 309 
LYS   H      H N N 310 
LYS   H2     H N N 311 
LYS   HA     H N N 312 
LYS   HB2    H N N 313 
LYS   HB3    H N N 314 
LYS   HG2    H N N 315 
LYS   HG3    H N N 316 
LYS   HD2    H N N 317 
LYS   HD3    H N N 318 
LYS   HE2    H N N 319 
LYS   HE3    H N N 320 
LYS   HZ1    H N N 321 
LYS   HZ2    H N N 322 
LYS   HZ3    H N N 323 
LYS   HXT    H N N 324 
MET   N      N N N 325 
MET   CA     C N S 326 
MET   C      C N N 327 
MET   O      O N N 328 
MET   CB     C N N 329 
MET   CG     C N N 330 
MET   SD     S N N 331 
MET   CE     C N N 332 
MET   OXT    O N N 333 
MET   H      H N N 334 
MET   H2     H N N 335 
MET   HA     H N N 336 
MET   HB2    H N N 337 
MET   HB3    H N N 338 
MET   HG2    H N N 339 
MET   HG3    H N N 340 
MET   HE1    H N N 341 
MET   HE2    H N N 342 
MET   HE3    H N N 343 
MET   HXT    H N N 344 
PHE   N      N N N 345 
PHE   CA     C N S 346 
PHE   C      C N N 347 
PHE   O      O N N 348 
PHE   CB     C N N 349 
PHE   CG     C Y N 350 
PHE   CD1    C Y N 351 
PHE   CD2    C Y N 352 
PHE   CE1    C Y N 353 
PHE   CE2    C Y N 354 
PHE   CZ     C Y N 355 
PHE   OXT    O N N 356 
PHE   H      H N N 357 
PHE   H2     H N N 358 
PHE   HA     H N N 359 
PHE   HB2    H N N 360 
PHE   HB3    H N N 361 
PHE   HD1    H N N 362 
PHE   HD2    H N N 363 
PHE   HE1    H N N 364 
PHE   HE2    H N N 365 
PHE   HZ     H N N 366 
PHE   HXT    H N N 367 
PRO   N      N N N 368 
PRO   CA     C N S 369 
PRO   C      C N N 370 
PRO   O      O N N 371 
PRO   CB     C N N 372 
PRO   CG     C N N 373 
PRO   CD     C N N 374 
PRO   OXT    O N N 375 
PRO   H      H N N 376 
PRO   HA     H N N 377 
PRO   HB2    H N N 378 
PRO   HB3    H N N 379 
PRO   HG2    H N N 380 
PRO   HG3    H N N 381 
PRO   HD2    H N N 382 
PRO   HD3    H N N 383 
PRO   HXT    H N N 384 
SER   N      N N N 385 
SER   CA     C N S 386 
SER   C      C N N 387 
SER   O      O N N 388 
SER   CB     C N N 389 
SER   OG     O N N 390 
SER   OXT    O N N 391 
SER   H      H N N 392 
SER   H2     H N N 393 
SER   HA     H N N 394 
SER   HB2    H N N 395 
SER   HB3    H N N 396 
SER   HG     H N N 397 
SER   HXT    H N N 398 
THR   N      N N N 399 
THR   CA     C N S 400 
THR   C      C N N 401 
THR   O      O N N 402 
THR   CB     C N R 403 
THR   OG1    O N N 404 
THR   CG2    C N N 405 
THR   OXT    O N N 406 
THR   H      H N N 407 
THR   H2     H N N 408 
THR   HA     H N N 409 
THR   HB     H N N 410 
THR   HG1    H N N 411 
THR   HG21   H N N 412 
THR   HG22   H N N 413 
THR   HG23   H N N 414 
THR   HXT    H N N 415 
TRP   N      N N N 416 
TRP   CA     C N S 417 
TRP   C      C N N 418 
TRP   O      O N N 419 
TRP   CB     C N N 420 
TRP   CG     C Y N 421 
TRP   CD1    C Y N 422 
TRP   CD2    C Y N 423 
TRP   NE1    N Y N 424 
TRP   CE2    C Y N 425 
TRP   CE3    C Y N 426 
TRP   CZ2    C Y N 427 
TRP   CZ3    C Y N 428 
TRP   CH2    C Y N 429 
TRP   OXT    O N N 430 
TRP   H      H N N 431 
TRP   H2     H N N 432 
TRP   HA     H N N 433 
TRP   HB2    H N N 434 
TRP   HB3    H N N 435 
TRP   HD1    H N N 436 
TRP   HE1    H N N 437 
TRP   HE3    H N N 438 
TRP   HZ2    H N N 439 
TRP   HZ3    H N N 440 
TRP   HH2    H N N 441 
TRP   HXT    H N N 442 
TYR   N      N N N 443 
TYR   CA     C N S 444 
TYR   C      C N N 445 
TYR   O      O N N 446 
TYR   CB     C N N 447 
TYR   CG     C Y N 448 
TYR   CD1    C Y N 449 
TYR   CD2    C Y N 450 
TYR   CE1    C Y N 451 
TYR   CE2    C Y N 452 
TYR   CZ     C Y N 453 
TYR   OH     O N N 454 
TYR   OXT    O N N 455 
TYR   H      H N N 456 
TYR   H2     H N N 457 
TYR   HA     H N N 458 
TYR   HB2    H N N 459 
TYR   HB3    H N N 460 
TYR   HD1    H N N 461 
TYR   HD2    H N N 462 
TYR   HE1    H N N 463 
TYR   HE2    H N N 464 
TYR   HH     H N N 465 
TYR   HXT    H N N 466 
U     OP3    O N N 467 
U     P      P N N 468 
U     OP1    O N N 469 
U     OP2    O N N 470 
U     "O5'"  O N N 471 
U     "C5'"  C N N 472 
U     "C4'"  C N R 473 
U     "O4'"  O N N 474 
U     "C3'"  C N S 475 
U     "O3'"  O N N 476 
U     "C2'"  C N R 477 
U     "O2'"  O N N 478 
U     "C1'"  C N R 479 
U     N1     N N N 480 
U     C2     C N N 481 
U     O2     O N N 482 
U     N3     N N N 483 
U     C4     C N N 484 
U     O4     O N N 485 
U     C5     C N N 486 
U     C6     C N N 487 
U     HOP3   H N N 488 
U     HOP2   H N N 489 
U     "H5'"  H N N 490 
U     "H5''" H N N 491 
U     "H4'"  H N N 492 
U     "H3'"  H N N 493 
U     "HO3'" H N N 494 
U     "H2'"  H N N 495 
U     "HO2'" H N N 496 
U     "H1'"  H N N 497 
U     H3     H N N 498 
U     H5     H N N 499 
U     H6     H N N 500 
VAL   N      N N N 501 
VAL   CA     C N S 502 
VAL   C      C N N 503 
VAL   O      O N N 504 
VAL   CB     C N N 505 
VAL   CG1    C N N 506 
VAL   CG2    C N N 507 
VAL   OXT    O N N 508 
VAL   H      H N N 509 
VAL   H2     H N N 510 
VAL   HA     H N N 511 
VAL   HB     H N N 512 
VAL   HG11   H N N 513 
VAL   HG12   H N N 514 
VAL   HG13   H N N 515 
VAL   HG21   H N N 516 
VAL   HG22   H N N 517 
VAL   HG23   H N N 518 
VAL   HXT    H N N 519 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1IJK C2    O5     sing N N 1   
A1IJK C2    C1     sing N N 2   
A1IJK C2    C3     sing N N 3   
A1IJK O19   C17    doub N N 4   
A1IJK C13   C12    doub Y N 5   
A1IJK C13   C14    sing Y N 6   
A1IJK C12   C11    sing Y N 7   
A1IJK O4    C3     sing N N 8   
A1IJK O4    C6     sing N N 9   
A1IJK N9    C8     sing N N 10  
A1IJK N9    C10    sing N N 11  
A1IJK C8    C7     sing N N 12  
A1IJK C17   C14    sing N N 13  
A1IJK C17   O18    sing N N 14  
A1IJK C14   C15    doub Y N 15  
A1IJK C11   C10    sing N N 16  
A1IJK C11   C16    doub Y N 17  
A1IJK C10   O26    doub N N 18  
A1IJK C6    C7     sing N N 19  
A1IJK C15   C16    sing Y N 20  
A1IJK C15   C20    sing N N 21  
A1IJK C29   C30    doub N N 22  
A1IJK C29   C28    sing N N 23  
A1IJK C30   C21    sing N N 24  
A1IJK C20   C21    doub Y N 25  
A1IJK C20   C25    sing Y N 26  
A1IJK C21   C22    sing Y N 27  
A1IJK C28   O35    doub N N 28  
A1IJK C28   C27    sing N N 29  
A1IJK C22   C27    sing N N 30  
A1IJK C22   O23    doub Y N 31  
A1IJK C25   C34    sing N N 32  
A1IJK C25   C24    doub Y N 33  
A1IJK C34   C33    doub N N 34  
A1IJK O23   C24    sing Y N 35  
A1IJK C24   C31    sing N N 36  
A1IJK C33   C32    sing N N 37  
A1IJK C31   C32    sing N N 38  
A1IJK C32   O36    doub N N 39  
A1IJK C1    H1     sing N N 40  
A1IJK C1    H2     sing N N 41  
A1IJK C1    H3     sing N N 42  
A1IJK C2    H4     sing N N 43  
A1IJK C3    H5     sing N N 44  
A1IJK C3    H6     sing N N 45  
A1IJK C6    H7     sing N N 46  
A1IJK C6    H8     sing N N 47  
A1IJK C7    H9     sing N N 48  
A1IJK C7    H10    sing N N 49  
A1IJK O5    H11    sing N N 50  
A1IJK C8    H12    sing N N 51  
A1IJK C8    H13    sing N N 52  
A1IJK N9    H14    sing N N 53  
A1IJK C33   H15    sing N N 54  
A1IJK C34   H16    sing N N 55  
A1IJK C12   H17    sing N N 56  
A1IJK C13   H18    sing N N 57  
A1IJK C16   H19    sing N N 58  
A1IJK C27   H20    sing N N 59  
A1IJK C27   H21    sing N N 60  
A1IJK C29   H22    sing N N 61  
A1IJK C30   H23    sing N N 62  
A1IJK C31   H24    sing N N 63  
A1IJK C31   H25    sing N N 64  
A1IJK O18   H26    sing N N 65  
A1IJK O23   H27    sing N N 66  
ALA   N     CA     sing N N 67  
ALA   N     H      sing N N 68  
ALA   N     H2     sing N N 69  
ALA   CA    C      sing N N 70  
ALA   CA    CB     sing N N 71  
ALA   CA    HA     sing N N 72  
ALA   C     O      doub N N 73  
ALA   C     OXT    sing N N 74  
ALA   CB    HB1    sing N N 75  
ALA   CB    HB2    sing N N 76  
ALA   CB    HB3    sing N N 77  
ALA   OXT   HXT    sing N N 78  
ARG   N     CA     sing N N 79  
ARG   N     H      sing N N 80  
ARG   N     H2     sing N N 81  
ARG   CA    C      sing N N 82  
ARG   CA    CB     sing N N 83  
ARG   CA    HA     sing N N 84  
ARG   C     O      doub N N 85  
ARG   C     OXT    sing N N 86  
ARG   CB    CG     sing N N 87  
ARG   CB    HB2    sing N N 88  
ARG   CB    HB3    sing N N 89  
ARG   CG    CD     sing N N 90  
ARG   CG    HG2    sing N N 91  
ARG   CG    HG3    sing N N 92  
ARG   CD    NE     sing N N 93  
ARG   CD    HD2    sing N N 94  
ARG   CD    HD3    sing N N 95  
ARG   NE    CZ     sing N N 96  
ARG   NE    HE     sing N N 97  
ARG   CZ    NH1    sing N N 98  
ARG   CZ    NH2    doub N N 99  
ARG   NH1   HH11   sing N N 100 
ARG   NH1   HH12   sing N N 101 
ARG   NH2   HH21   sing N N 102 
ARG   NH2   HH22   sing N N 103 
ARG   OXT   HXT    sing N N 104 
ASN   N     CA     sing N N 105 
ASN   N     H      sing N N 106 
ASN   N     H2     sing N N 107 
ASN   CA    C      sing N N 108 
ASN   CA    CB     sing N N 109 
ASN   CA    HA     sing N N 110 
ASN   C     O      doub N N 111 
ASN   C     OXT    sing N N 112 
ASN   CB    CG     sing N N 113 
ASN   CB    HB2    sing N N 114 
ASN   CB    HB3    sing N N 115 
ASN   CG    OD1    doub N N 116 
ASN   CG    ND2    sing N N 117 
ASN   ND2   HD21   sing N N 118 
ASN   ND2   HD22   sing N N 119 
ASN   OXT   HXT    sing N N 120 
ASP   N     CA     sing N N 121 
ASP   N     H      sing N N 122 
ASP   N     H2     sing N N 123 
ASP   CA    C      sing N N 124 
ASP   CA    CB     sing N N 125 
ASP   CA    HA     sing N N 126 
ASP   C     O      doub N N 127 
ASP   C     OXT    sing N N 128 
ASP   CB    CG     sing N N 129 
ASP   CB    HB2    sing N N 130 
ASP   CB    HB3    sing N N 131 
ASP   CG    OD1    doub N N 132 
ASP   CG    OD2    sing N N 133 
ASP   OD2   HD2    sing N N 134 
ASP   OXT   HXT    sing N N 135 
C     OP3   P      sing N N 136 
C     OP3   HOP3   sing N N 137 
C     P     OP1    doub N N 138 
C     P     OP2    sing N N 139 
C     P     "O5'"  sing N N 140 
C     OP2   HOP2   sing N N 141 
C     "O5'" "C5'"  sing N N 142 
C     "C5'" "C4'"  sing N N 143 
C     "C5'" "H5'"  sing N N 144 
C     "C5'" "H5''" sing N N 145 
C     "C4'" "O4'"  sing N N 146 
C     "C4'" "C3'"  sing N N 147 
C     "C4'" "H4'"  sing N N 148 
C     "O4'" "C1'"  sing N N 149 
C     "C3'" "O3'"  sing N N 150 
C     "C3'" "C2'"  sing N N 151 
C     "C3'" "H3'"  sing N N 152 
C     "O3'" "HO3'" sing N N 153 
C     "C2'" "O2'"  sing N N 154 
C     "C2'" "C1'"  sing N N 155 
C     "C2'" "H2'"  sing N N 156 
C     "O2'" "HO2'" sing N N 157 
C     "C1'" N1     sing N N 158 
C     "C1'" "H1'"  sing N N 159 
C     N1    C2     sing N N 160 
C     N1    C6     sing N N 161 
C     C2    O2     doub N N 162 
C     C2    N3     sing N N 163 
C     N3    C4     doub N N 164 
C     C4    N4     sing N N 165 
C     C4    C5     sing N N 166 
C     N4    H41    sing N N 167 
C     N4    H42    sing N N 168 
C     C5    C6     doub N N 169 
C     C5    H5     sing N N 170 
C     C6    H6     sing N N 171 
CYS   N     CA     sing N N 172 
CYS   N     H      sing N N 173 
CYS   N     H2     sing N N 174 
CYS   CA    C      sing N N 175 
CYS   CA    CB     sing N N 176 
CYS   CA    HA     sing N N 177 
CYS   C     O      doub N N 178 
CYS   C     OXT    sing N N 179 
CYS   CB    SG     sing N N 180 
CYS   CB    HB2    sing N N 181 
CYS   CB    HB3    sing N N 182 
CYS   SG    HG     sing N N 183 
CYS   OXT   HXT    sing N N 184 
GLN   N     CA     sing N N 185 
GLN   N     H      sing N N 186 
GLN   N     H2     sing N N 187 
GLN   CA    C      sing N N 188 
GLN   CA    CB     sing N N 189 
GLN   CA    HA     sing N N 190 
GLN   C     O      doub N N 191 
GLN   C     OXT    sing N N 192 
GLN   CB    CG     sing N N 193 
GLN   CB    HB2    sing N N 194 
GLN   CB    HB3    sing N N 195 
GLN   CG    CD     sing N N 196 
GLN   CG    HG2    sing N N 197 
GLN   CG    HG3    sing N N 198 
GLN   CD    OE1    doub N N 199 
GLN   CD    NE2    sing N N 200 
GLN   NE2   HE21   sing N N 201 
GLN   NE2   HE22   sing N N 202 
GLN   OXT   HXT    sing N N 203 
GLU   N     CA     sing N N 204 
GLU   N     H      sing N N 205 
GLU   N     H2     sing N N 206 
GLU   CA    C      sing N N 207 
GLU   CA    CB     sing N N 208 
GLU   CA    HA     sing N N 209 
GLU   C     O      doub N N 210 
GLU   C     OXT    sing N N 211 
GLU   CB    CG     sing N N 212 
GLU   CB    HB2    sing N N 213 
GLU   CB    HB3    sing N N 214 
GLU   CG    CD     sing N N 215 
GLU   CG    HG2    sing N N 216 
GLU   CG    HG3    sing N N 217 
GLU   CD    OE1    doub N N 218 
GLU   CD    OE2    sing N N 219 
GLU   OE2   HE2    sing N N 220 
GLU   OXT   HXT    sing N N 221 
GLY   N     CA     sing N N 222 
GLY   N     H      sing N N 223 
GLY   N     H2     sing N N 224 
GLY   CA    C      sing N N 225 
GLY   CA    HA2    sing N N 226 
GLY   CA    HA3    sing N N 227 
GLY   C     O      doub N N 228 
GLY   C     OXT    sing N N 229 
GLY   OXT   HXT    sing N N 230 
HIS   N     CA     sing N N 231 
HIS   N     H      sing N N 232 
HIS   N     H2     sing N N 233 
HIS   CA    C      sing N N 234 
HIS   CA    CB     sing N N 235 
HIS   CA    HA     sing N N 236 
HIS   C     O      doub N N 237 
HIS   C     OXT    sing N N 238 
HIS   CB    CG     sing N N 239 
HIS   CB    HB2    sing N N 240 
HIS   CB    HB3    sing N N 241 
HIS   CG    ND1    sing Y N 242 
HIS   CG    CD2    doub Y N 243 
HIS   ND1   CE1    doub Y N 244 
HIS   ND1   HD1    sing N N 245 
HIS   CD2   NE2    sing Y N 246 
HIS   CD2   HD2    sing N N 247 
HIS   CE1   NE2    sing Y N 248 
HIS   CE1   HE1    sing N N 249 
HIS   NE2   HE2    sing N N 250 
HIS   OXT   HXT    sing N N 251 
ILE   N     CA     sing N N 252 
ILE   N     H      sing N N 253 
ILE   N     H2     sing N N 254 
ILE   CA    C      sing N N 255 
ILE   CA    CB     sing N N 256 
ILE   CA    HA     sing N N 257 
ILE   C     O      doub N N 258 
ILE   C     OXT    sing N N 259 
ILE   CB    CG1    sing N N 260 
ILE   CB    CG2    sing N N 261 
ILE   CB    HB     sing N N 262 
ILE   CG1   CD1    sing N N 263 
ILE   CG1   HG12   sing N N 264 
ILE   CG1   HG13   sing N N 265 
ILE   CG2   HG21   sing N N 266 
ILE   CG2   HG22   sing N N 267 
ILE   CG2   HG23   sing N N 268 
ILE   CD1   HD11   sing N N 269 
ILE   CD1   HD12   sing N N 270 
ILE   CD1   HD13   sing N N 271 
ILE   OXT   HXT    sing N N 272 
LEU   N     CA     sing N N 273 
LEU   N     H      sing N N 274 
LEU   N     H2     sing N N 275 
LEU   CA    C      sing N N 276 
LEU   CA    CB     sing N N 277 
LEU   CA    HA     sing N N 278 
LEU   C     O      doub N N 279 
LEU   C     OXT    sing N N 280 
LEU   CB    CG     sing N N 281 
LEU   CB    HB2    sing N N 282 
LEU   CB    HB3    sing N N 283 
LEU   CG    CD1    sing N N 284 
LEU   CG    CD2    sing N N 285 
LEU   CG    HG     sing N N 286 
LEU   CD1   HD11   sing N N 287 
LEU   CD1   HD12   sing N N 288 
LEU   CD1   HD13   sing N N 289 
LEU   CD2   HD21   sing N N 290 
LEU   CD2   HD22   sing N N 291 
LEU   CD2   HD23   sing N N 292 
LEU   OXT   HXT    sing N N 293 
LYS   N     CA     sing N N 294 
LYS   N     H      sing N N 295 
LYS   N     H2     sing N N 296 
LYS   CA    C      sing N N 297 
LYS   CA    CB     sing N N 298 
LYS   CA    HA     sing N N 299 
LYS   C     O      doub N N 300 
LYS   C     OXT    sing N N 301 
LYS   CB    CG     sing N N 302 
LYS   CB    HB2    sing N N 303 
LYS   CB    HB3    sing N N 304 
LYS   CG    CD     sing N N 305 
LYS   CG    HG2    sing N N 306 
LYS   CG    HG3    sing N N 307 
LYS   CD    CE     sing N N 308 
LYS   CD    HD2    sing N N 309 
LYS   CD    HD3    sing N N 310 
LYS   CE    NZ     sing N N 311 
LYS   CE    HE2    sing N N 312 
LYS   CE    HE3    sing N N 313 
LYS   NZ    HZ1    sing N N 314 
LYS   NZ    HZ2    sing N N 315 
LYS   NZ    HZ3    sing N N 316 
LYS   OXT   HXT    sing N N 317 
MET   N     CA     sing N N 318 
MET   N     H      sing N N 319 
MET   N     H2     sing N N 320 
MET   CA    C      sing N N 321 
MET   CA    CB     sing N N 322 
MET   CA    HA     sing N N 323 
MET   C     O      doub N N 324 
MET   C     OXT    sing N N 325 
MET   CB    CG     sing N N 326 
MET   CB    HB2    sing N N 327 
MET   CB    HB3    sing N N 328 
MET   CG    SD     sing N N 329 
MET   CG    HG2    sing N N 330 
MET   CG    HG3    sing N N 331 
MET   SD    CE     sing N N 332 
MET   CE    HE1    sing N N 333 
MET   CE    HE2    sing N N 334 
MET   CE    HE3    sing N N 335 
MET   OXT   HXT    sing N N 336 
PHE   N     CA     sing N N 337 
PHE   N     H      sing N N 338 
PHE   N     H2     sing N N 339 
PHE   CA    C      sing N N 340 
PHE   CA    CB     sing N N 341 
PHE   CA    HA     sing N N 342 
PHE   C     O      doub N N 343 
PHE   C     OXT    sing N N 344 
PHE   CB    CG     sing N N 345 
PHE   CB    HB2    sing N N 346 
PHE   CB    HB3    sing N N 347 
PHE   CG    CD1    doub Y N 348 
PHE   CG    CD2    sing Y N 349 
PHE   CD1   CE1    sing Y N 350 
PHE   CD1   HD1    sing N N 351 
PHE   CD2   CE2    doub Y N 352 
PHE   CD2   HD2    sing N N 353 
PHE   CE1   CZ     doub Y N 354 
PHE   CE1   HE1    sing N N 355 
PHE   CE2   CZ     sing Y N 356 
PHE   CE2   HE2    sing N N 357 
PHE   CZ    HZ     sing N N 358 
PHE   OXT   HXT    sing N N 359 
PRO   N     CA     sing N N 360 
PRO   N     CD     sing N N 361 
PRO   N     H      sing N N 362 
PRO   CA    C      sing N N 363 
PRO   CA    CB     sing N N 364 
PRO   CA    HA     sing N N 365 
PRO   C     O      doub N N 366 
PRO   C     OXT    sing N N 367 
PRO   CB    CG     sing N N 368 
PRO   CB    HB2    sing N N 369 
PRO   CB    HB3    sing N N 370 
PRO   CG    CD     sing N N 371 
PRO   CG    HG2    sing N N 372 
PRO   CG    HG3    sing N N 373 
PRO   CD    HD2    sing N N 374 
PRO   CD    HD3    sing N N 375 
PRO   OXT   HXT    sing N N 376 
SER   N     CA     sing N N 377 
SER   N     H      sing N N 378 
SER   N     H2     sing N N 379 
SER   CA    C      sing N N 380 
SER   CA    CB     sing N N 381 
SER   CA    HA     sing N N 382 
SER   C     O      doub N N 383 
SER   C     OXT    sing N N 384 
SER   CB    OG     sing N N 385 
SER   CB    HB2    sing N N 386 
SER   CB    HB3    sing N N 387 
SER   OG    HG     sing N N 388 
SER   OXT   HXT    sing N N 389 
THR   N     CA     sing N N 390 
THR   N     H      sing N N 391 
THR   N     H2     sing N N 392 
THR   CA    C      sing N N 393 
THR   CA    CB     sing N N 394 
THR   CA    HA     sing N N 395 
THR   C     O      doub N N 396 
THR   C     OXT    sing N N 397 
THR   CB    OG1    sing N N 398 
THR   CB    CG2    sing N N 399 
THR   CB    HB     sing N N 400 
THR   OG1   HG1    sing N N 401 
THR   CG2   HG21   sing N N 402 
THR   CG2   HG22   sing N N 403 
THR   CG2   HG23   sing N N 404 
THR   OXT   HXT    sing N N 405 
TRP   N     CA     sing N N 406 
TRP   N     H      sing N N 407 
TRP   N     H2     sing N N 408 
TRP   CA    C      sing N N 409 
TRP   CA    CB     sing N N 410 
TRP   CA    HA     sing N N 411 
TRP   C     O      doub N N 412 
TRP   C     OXT    sing N N 413 
TRP   CB    CG     sing N N 414 
TRP   CB    HB2    sing N N 415 
TRP   CB    HB3    sing N N 416 
TRP   CG    CD1    doub Y N 417 
TRP   CG    CD2    sing Y N 418 
TRP   CD1   NE1    sing Y N 419 
TRP   CD1   HD1    sing N N 420 
TRP   CD2   CE2    doub Y N 421 
TRP   CD2   CE3    sing Y N 422 
TRP   NE1   CE2    sing Y N 423 
TRP   NE1   HE1    sing N N 424 
TRP   CE2   CZ2    sing Y N 425 
TRP   CE3   CZ3    doub Y N 426 
TRP   CE3   HE3    sing N N 427 
TRP   CZ2   CH2    doub Y N 428 
TRP   CZ2   HZ2    sing N N 429 
TRP   CZ3   CH2    sing Y N 430 
TRP   CZ3   HZ3    sing N N 431 
TRP   CH2   HH2    sing N N 432 
TRP   OXT   HXT    sing N N 433 
TYR   N     CA     sing N N 434 
TYR   N     H      sing N N 435 
TYR   N     H2     sing N N 436 
TYR   CA    C      sing N N 437 
TYR   CA    CB     sing N N 438 
TYR   CA    HA     sing N N 439 
TYR   C     O      doub N N 440 
TYR   C     OXT    sing N N 441 
TYR   CB    CG     sing N N 442 
TYR   CB    HB2    sing N N 443 
TYR   CB    HB3    sing N N 444 
TYR   CG    CD1    doub Y N 445 
TYR   CG    CD2    sing Y N 446 
TYR   CD1   CE1    sing Y N 447 
TYR   CD1   HD1    sing N N 448 
TYR   CD2   CE2    doub Y N 449 
TYR   CD2   HD2    sing N N 450 
TYR   CE1   CZ     doub Y N 451 
TYR   CE1   HE1    sing N N 452 
TYR   CE2   CZ     sing Y N 453 
TYR   CE2   HE2    sing N N 454 
TYR   CZ    OH     sing N N 455 
TYR   OH    HH     sing N N 456 
TYR   OXT   HXT    sing N N 457 
U     OP3   P      sing N N 458 
U     OP3   HOP3   sing N N 459 
U     P     OP1    doub N N 460 
U     P     OP2    sing N N 461 
U     P     "O5'"  sing N N 462 
U     OP2   HOP2   sing N N 463 
U     "O5'" "C5'"  sing N N 464 
U     "C5'" "C4'"  sing N N 465 
U     "C5'" "H5'"  sing N N 466 
U     "C5'" "H5''" sing N N 467 
U     "C4'" "O4'"  sing N N 468 
U     "C4'" "C3'"  sing N N 469 
U     "C4'" "H4'"  sing N N 470 
U     "O4'" "C1'"  sing N N 471 
U     "C3'" "O3'"  sing N N 472 
U     "C3'" "C2'"  sing N N 473 
U     "C3'" "H3'"  sing N N 474 
U     "O3'" "HO3'" sing N N 475 
U     "C2'" "O2'"  sing N N 476 
U     "C2'" "C1'"  sing N N 477 
U     "C2'" "H2'"  sing N N 478 
U     "O2'" "HO2'" sing N N 479 
U     "C1'" N1     sing N N 480 
U     "C1'" "H1'"  sing N N 481 
U     N1    C2     sing N N 482 
U     N1    C6     sing N N 483 
U     C2    O2     doub N N 484 
U     C2    N3     sing N N 485 
U     N3    C4     sing N N 486 
U     N3    H3     sing N N 487 
U     C4    O4     doub N N 488 
U     C4    C5     sing N N 489 
U     C5    C6     doub N N 490 
U     C5    H5     sing N N 491 
U     C6    H6     sing N N 492 
VAL   N     CA     sing N N 493 
VAL   N     H      sing N N 494 
VAL   N     H2     sing N N 495 
VAL   CA    C      sing N N 496 
VAL   CA    CB     sing N N 497 
VAL   CA    HA     sing N N 498 
VAL   C     O      doub N N 499 
VAL   C     OXT    sing N N 500 
VAL   CB    CG1    sing N N 501 
VAL   CB    CG2    sing N N 502 
VAL   CB    HB     sing N N 503 
VAL   CG1   HG11   sing N N 504 
VAL   CG1   HG12   sing N N 505 
VAL   CG1   HG13   sing N N 506 
VAL   CG2   HG21   sing N N 507 
VAL   CG2   HG22   sing N N 508 
VAL   CG2   HG23   sing N N 509 
VAL   OXT   HXT    sing N N 510 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-29 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9GAP 
_em_admin.last_update        2025-02-12 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              'CryoEM structure of influenza A RNP-like particle double-stranded assembled with a 12-mer RNA.' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 20  mM ?    1 HEPES                   
1 150 mM NaCl 2 NaCl                    
1 5   mM ?    3 beta-mercaptoethanol    
1 2   mM ?    4 methyl-PEG8-NHS         
1 4   uM ?    5 
;RNA (5'P-(UC)6-FAM3')
;
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 2 2 32630 'synthetic construct' ? ? ? ? ? 
? ? 3 3 11320 'Influenza A virus'   ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 2 2 32630  'synthetic construct'        ? ? 
? 3 3 469008 'Escherichia coli BL21(DE3)' ? ? 
# 
_em_helical_entity.id                             1 
_em_helical_entity.image_processing_id            1 
_em_helical_entity.details                        ? 
_em_helical_entity.axial_symmetry                 C2 
_em_helical_entity.angular_rotation_per_subunit   57.53 
_em_helical_entity.axial_rise_per_subunit         23.87 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?        ?            
'MODEL REFINEMENT'              ? 2  ? ? ? PHENIX   1.20.1_4487: 
'IMAGE ACQUISITION'             ? 3  ? ? 1 SerialEM ?            
MASKING                         ? 4  ? ? ? ?        ?            
'CTF CORRECTION'                ? 5  1 ? ? ?        ?            
'LAYERLINE INDEXING'            ? 6  ? ? ? ?        ?            
'DIFFRACTION INDEXING'          ? 7  ? ? ? ?        ?            
'MODEL FITTING'                 ? 8  ? ? ? ?        ?            
OTHER                           ? 9  ? ? ? ?        ?            
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?        ?            
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?        ?            
CLASSIFICATION                  ? 12 1 ? ? ?        ?            
RECONSTRUCTION                  ? 13 1 ? ? ?        ?            
'VOLUME SELECTION'              ? 14 1 1 1 ?        ?            
'SERIES ALIGNMENT'              ? 15 1 1 1 ?        ?            
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?        ?            
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?        ?            
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?        ?            
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?        ?            
# 
_em_specimen.concentration           0.23 
_em_specimen.details                 
;20 mM HEPES
150 mM NaCl
5 mM betamercaptoethanol
Incubation overnight with 0.004 uM RNA.
Prior freezing, the sample was incubated with 2 mM methyl PEG8 N hydroxysuccinimide ester reagent.
;
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Agence Nationale de la Recherche (ANR)'                          France ANR-23-CE11-01      1 
'Grenoble Alliance for Integrated Structural Cell Biology (GRAL)' France ANR-17-EURE-0003    2 
'Grenoble Instruct-ERIC Center (ISBG)'                            France ANR-10-INSB-0005-02 3 
# 
_atom_sites.entry_id                    9GAP 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    P P     . U     A 1 1   ? 212.064 253.555 222.525 1.00 59.56  ? 7   U     C P     1 
ATOM   2    O OP1   . U     A 1 1   ? 210.967 254.397 221.990 1.00 56.78  ? 7   U     C OP1   1 
ATOM   3    O OP2   . U     A 1 1   ? 212.603 253.832 223.879 1.00 58.18  ? 7   U     C OP2   1 
ATOM   4    O "O5'" . U     A 1 1   ? 211.573 252.040 222.495 1.00 62.06  ? 7   U     C "O5'" 1 
ATOM   5    C "C5'" . U     A 1 1   ? 210.723 251.569 221.457 1.00 59.03  ? 7   U     C "C5'" 1 
ATOM   6    C "C4'" . U     A 1 1   ? 210.098 250.237 221.796 1.00 61.90  ? 7   U     C "C4'" 1 
ATOM   7    O "O4'" . U     A 1 1   ? 211.096 249.186 221.681 1.00 63.47  ? 7   U     C "O4'" 1 
ATOM   8    C "C3'" . U     A 1 1   ? 209.509 250.119 223.203 1.00 61.60  ? 7   U     C "C3'" 1 
ATOM   9    O "O3'" . U     A 1 1   ? 208.333 249.314 223.154 1.00 62.13  ? 7   U     C "O3'" 1 
ATOM   10   C "C2'" . U     A 1 1   ? 210.598 249.368 223.962 1.00 62.24  ? 7   U     C "C2'" 1 
ATOM   11   O "O2'" . U     A 1 1   ? 210.141 248.652 225.090 1.00 67.62  ? 7   U     C "O2'" 1 
ATOM   12   C "C1'" . U     A 1 1   ? 211.132 248.437 222.880 1.00 62.49  ? 7   U     C "C1'" 1 
ATOM   13   N N1    . U     A 1 1   ? 212.505 247.955 223.102 1.00 61.17  ? 7   U     C N1    1 
ATOM   14   C C2    . U     A 1 1   ? 213.568 248.840 223.055 1.00 63.57  ? 7   U     C C2    1 
ATOM   15   O O2    . U     A 1 1   ? 213.453 250.031 222.836 1.00 67.27  ? 7   U     C O2    1 
ATOM   16   N N3    . U     A 1 1   ? 214.799 248.277 223.273 1.00 62.09  ? 7   U     C N3    1 
ATOM   17   C C4    . U     A 1 1   ? 215.075 246.953 223.531 1.00 64.42  ? 7   U     C C4    1 
ATOM   18   O O4    . U     A 1 1   ? 216.242 246.602 223.708 1.00 71.79  ? 7   U     C O4    1 
ATOM   19   C C5    . U     A 1 1   ? 213.929 246.102 223.563 1.00 57.88  ? 7   U     C C5    1 
ATOM   20   C C6    . U     A 1 1   ? 212.718 246.622 223.352 1.00 57.25  ? 7   U     C C6    1 
ATOM   21   P P     . C     A 1 2   ? 206.882 250.001 223.106 1.00 60.53  ? 8   C     C P     1 
ATOM   22   O OP1   . C     A 1 2   ? 207.047 251.398 222.636 1.00 62.50  ? 8   C     C OP1   1 
ATOM   23   O OP2   . C     A 1 2   ? 206.198 249.739 224.395 1.00 59.65  ? 8   C     C OP2   1 
ATOM   24   O "O5'" . C     A 1 2   ? 206.120 249.197 221.964 1.00 58.96  ? 8   C     C "O5'" 1 
ATOM   25   C "C5'" . C     A 1 2   ? 206.081 249.688 220.634 1.00 59.93  ? 8   C     C "C5'" 1 
ATOM   26   C "C4'" . C     A 1 2   ? 205.971 248.570 219.629 1.00 63.39  ? 8   C     C "C4'" 1 
ATOM   27   O "O4'" . C     A 1 2   ? 207.252 247.914 219.466 1.00 63.05  ? 8   C     C "O4'" 1 
ATOM   28   C "C3'" . C     A 1 2   ? 205.025 247.435 219.981 1.00 62.44  ? 8   C     C "C3'" 1 
ATOM   29   O "O3'" . C     A 1 2   ? 203.668 247.753 219.735 1.00 65.57  ? 8   C     C "O3'" 1 
ATOM   30   C "C2'" . C     A 1 2   ? 205.547 246.293 219.121 1.00 62.43  ? 8   C     C "C2'" 1 
ATOM   31   O "O2'" . C     A 1 2   ? 205.096 246.427 217.782 1.00 66.53  ? 8   C     C "O2'" 1 
ATOM   32   C "C1'" . C     A 1 2   ? 207.056 246.552 219.149 1.00 61.98  ? 8   C     C "C1'" 1 
ATOM   33   N N1    . C     A 1 2   ? 207.751 245.715 220.152 1.00 61.44  ? 8   C     C N1    1 
ATOM   34   C C2    . C     A 1 2   ? 208.068 244.400 219.807 1.00 61.12  ? 8   C     C C2    1 
ATOM   35   O O2    . C     A 1 2   ? 207.758 243.982 218.684 1.00 65.38  ? 8   C     C O2    1 
ATOM   36   N N3    . C     A 1 2   ? 208.702 243.613 220.700 1.00 58.03  ? 8   C     C N3    1 
ATOM   37   C C4    . C     A 1 2   ? 209.017 244.096 221.899 1.00 58.84  ? 8   C     C C4    1 
ATOM   38   N N4    . C     A 1 2   ? 209.643 243.281 222.746 1.00 58.92  ? 8   C     C N4    1 
ATOM   39   C C5    . C     A 1 2   ? 208.711 245.434 222.279 1.00 56.71  ? 8   C     C C5    1 
ATOM   40   C C6    . C     A 1 2   ? 208.081 246.202 221.384 1.00 59.81  ? 8   C     C C6    1 
ATOM   41   P P     . U     A 1 3   ? 202.524 247.243 220.741 1.00 70.26  ? 9   U     C P     1 
ATOM   42   O OP1   . U     A 1 3   ? 202.805 247.818 222.078 1.00 68.76  ? 9   U     C OP1   1 
ATOM   43   O OP2   . U     A 1 3   ? 202.390 245.775 220.579 1.00 66.96  ? 9   U     C OP2   1 
ATOM   44   O "O5'" . U     A 1 3   ? 201.195 247.923 220.189 1.00 64.93  ? 9   U     C "O5'" 1 
ATOM   45   C "C5'" . U     A 1 3   ? 200.800 249.219 220.625 1.00 60.18  ? 9   U     C "C5'" 1 
ATOM   46   C "C4'" . U     A 1 3   ? 200.559 250.149 219.463 1.00 59.33  ? 9   U     C "C4'" 1 
ATOM   47   O "O4'" . U     A 1 3   ? 199.554 251.132 219.832 1.00 59.86  ? 9   U     C "O4'" 1 
ATOM   48   C "C3'" . U     A 1 3   ? 201.779 250.943 219.003 1.00 61.53  ? 9   U     C "C3'" 1 
ATOM   49   O "O3'" . U     A 1 3   ? 201.696 251.160 217.597 1.00 65.64  ? 9   U     C "O3'" 1 
ATOM   50   C "C2'" . U     A 1 3   ? 201.596 252.273 219.721 1.00 63.14  ? 9   U     C "C2'" 1 
ATOM   51   O "O2'" . U     A 1 3   ? 202.258 253.363 219.117 1.00 71.84  ? 9   U     C "O2'" 1 
ATOM   52   C "C1'" . U     A 1 3   ? 200.080 252.433 219.668 1.00 61.24  ? 9   U     C "C1'" 1 
ATOM   53   N N1    . U     A 1 3   ? 199.526 253.311 220.709 1.00 61.01  ? 9   U     C N1    1 
ATOM   54   C C2    . U     A 1 3   ? 199.435 252.863 222.014 1.00 67.52  ? 9   U     C C2    1 
ATOM   55   O O2    . U     A 1 3   ? 199.793 251.758 222.385 1.00 74.44  ? 9   U     C O2    1 
ATOM   56   N N3    . U     A 1 3   ? 198.906 253.766 222.897 1.00 64.94  ? 9   U     C N3    1 
ATOM   57   C C4    . U     A 1 3   ? 198.469 255.042 222.623 1.00 64.23  ? 9   U     C C4    1 
ATOM   58   O O4    . U     A 1 3   ? 198.014 255.735 223.533 1.00 70.96  ? 9   U     C O4    1 
ATOM   59   C C5    . U     A 1 3   ? 198.592 255.431 221.255 1.00 59.38  ? 9   U     C C5    1 
ATOM   60   C C6    . U     A 1 3   ? 199.103 254.573 220.371 1.00 57.59  ? 9   U     C C6    1 
ATOM   61   P P     . C     A 1 4   ? 202.525 250.231 216.584 1.00 65.86  ? 10  C     C P     1 
ATOM   62   O OP1   . C     A 1 4   ? 203.940 250.204 217.030 1.00 65.92  ? 10  C     C OP1   1 
ATOM   63   O OP2   . C     A 1 4   ? 202.200 250.661 215.202 1.00 61.86  ? 10  C     C OP2   1 
ATOM   64   O "O5'" . C     A 1 4   ? 201.911 248.780 216.806 1.00 61.82  ? 10  C     C "O5'" 1 
ATOM   65   C "C5'" . C     A 1 4   ? 201.698 247.910 215.703 1.00 60.34  ? 10  C     C "C5'" 1 
ATOM   66   C "C4'" . C     A 1 4   ? 200.486 247.038 215.908 1.00 58.22  ? 10  C     C "C4'" 1 
ATOM   67   O "O4'" . C     A 1 4   ? 199.456 247.803 216.592 1.00 58.74  ? 10  C     C "O4'" 1 
ATOM   68   C "C3'" . C     A 1 4   ? 199.845 246.517 214.625 1.00 61.57  ? 10  C     C "C3'" 1 
ATOM   69   O "O3'" . C     A 1 4   ? 199.284 245.229 214.867 1.00 68.73  ? 10  C     C "O3'" 1 
ATOM   70   C "C2'" . C     A 1 4   ? 198.726 247.525 214.383 1.00 59.23  ? 10  C     C "C2'" 1 
ATOM   71   O "O2'" . C     A 1 4   ? 197.664 247.044 213.589 1.00 66.48  ? 10  C     C "O2'" 1 
ATOM   72   C "C1'" . C     A 1 4   ? 198.279 247.825 215.809 1.00 57.08  ? 10  C     C "C1'" 1 
ATOM   73   N N1    . C     A 1 4   ? 197.634 249.134 215.980 1.00 56.06  ? 10  C     C N1    1 
ATOM   74   C C2    . C     A 1 4   ? 196.248 249.184 216.126 1.00 55.85  ? 10  C     C C2    1 
ATOM   75   O O2    . C     A 1 4   ? 195.608 248.127 216.092 1.00 59.78  ? 10  C     C O2    1 
ATOM   76   N N3    . C     A 1 4   ? 195.640 250.379 216.293 1.00 47.71  ? 10  C     C N3    1 
ATOM   77   C C4    . C     A 1 4   ? 196.368 251.494 216.323 1.00 43.83  ? 10  C     C C4    1 
ATOM   78   N N4    . C     A 1 4   ? 195.728 252.650 216.488 1.00 42.85  ? 10  C     C N4    1 
ATOM   79   C C5    . C     A 1 4   ? 197.784 251.473 216.183 1.00 50.50  ? 10  C     C C5    1 
ATOM   80   C C6    . C     A 1 4   ? 198.371 250.282 216.018 1.00 55.83  ? 10  C     C C6    1 
ATOM   81   P P     . U     A 1 5   ? 200.046 243.905 214.367 1.00 74.97  ? 11  U     C P     1 
ATOM   82   O OP1   . U     A 1 5   ? 199.022 242.860 214.126 1.00 76.18  ? 11  U     C OP1   1 
ATOM   83   O OP2   . U     A 1 5   ? 201.169 243.627 215.297 1.00 67.01  ? 11  U     C OP2   1 
ATOM   84   O "O5'" . U     A 1 5   ? 200.657 244.319 212.957 1.00 71.67  ? 11  U     C "O5'" 1 
ATOM   85   C "C5'" . U     A 1 5   ? 199.881 244.219 211.773 1.00 68.89  ? 11  U     C "C5'" 1 
ATOM   86   C "C4'" . U     A 1 5   ? 200.742 244.320 210.540 1.00 76.46  ? 11  U     C "C4'" 1 
ATOM   87   O "O4'" . U     A 1 5   ? 201.123 245.700 210.312 1.00 78.30  ? 11  U     C "O4'" 1 
ATOM   88   C "C3'" . U     A 1 5   ? 202.067 243.575 210.587 1.00 81.81  ? 11  U     C "C3'" 1 
ATOM   89   O "O3'" . U     A 1 5   ? 201.932 242.193 210.315 1.00 87.27  ? 11  U     C "O3'" 1 
ATOM   90   C "C2'" . U     A 1 5   ? 202.897 244.317 209.551 1.00 84.31  ? 11  U     C "C2'" 1 
ATOM   91   O "O2'" . U     A 1 5   ? 202.541 243.906 208.241 1.00 84.74  ? 11  U     C "O2'" 1 
ATOM   92   C "C1'" . U     A 1 5   ? 202.417 245.756 209.754 1.00 83.58  ? 11  U     C "C1'" 1 
ATOM   93   N N1    . U     A 1 5   ? 203.293 246.512 210.674 1.00 80.38  ? 11  U     C N1    1 
ATOM   94   C C2    . U     A 1 5   ? 204.532 246.907 210.214 1.00 86.42  ? 11  U     C C2    1 
ATOM   95   O O2    . U     A 1 5   ? 204.933 246.656 209.091 1.00 93.68  ? 11  U     C O2    1 
ATOM   96   N N3    . U     A 1 5   ? 205.289 247.604 211.118 1.00 85.25  ? 11  U     C N3    1 
ATOM   97   C C4    . U     A 1 5   ? 204.941 247.944 212.407 1.00 81.29  ? 11  U     C C4    1 
ATOM   98   O O4    . U     A 1 5   ? 205.734 248.577 213.103 1.00 84.94  ? 11  U     C O4    1 
ATOM   99   C C5    . U     A 1 5   ? 203.644 247.503 212.806 1.00 77.72  ? 11  U     C C5    1 
ATOM   100  C C6    . U     A 1 5   ? 202.883 246.821 211.947 1.00 77.32  ? 11  U     C C6    1 
ATOM   101  P P     . C     A 1 6   ? 203.166 241.195 210.563 1.00 91.55  ? 12  C     C P     1 
ATOM   102  O OP1   . C     A 1 6   ? 204.225 241.936 211.356 1.00 84.24  ? 12  C     C OP1   1 
ATOM   103  O "O5'" . C     A 1 6   ? 202.555 240.059 211.498 1.00 86.99  ? 12  C     C "O5'" 1 
ATOM   104  C "C5'" . C     A 1 6   ? 201.969 240.389 212.747 1.00 84.42  ? 12  C     C "C5'" 1 
ATOM   105  C "C4'" . C     A 1 6   ? 200.863 239.435 213.122 1.00 89.41  ? 12  C     C "C4'" 1 
ATOM   106  O "O4'" . C     A 1 6   ? 199.873 239.385 212.071 1.00 86.79  ? 12  C     C "O4'" 1 
ATOM   107  C "C3'" . C     A 1 6   ? 201.265 237.983 213.315 1.00 92.98  ? 12  C     C "C3'" 1 
ATOM   108  O "O3'" . C     A 1 6   ? 201.844 237.748 214.587 1.00 92.19  ? 12  C     C "O3'" 1 
ATOM   109  C "C2'" . C     A 1 6   ? 199.949 237.233 213.106 1.00 94.70  ? 12  C     C "C2'" 1 
ATOM   110  O "O2'" . C     A 1 6   ? 199.199 237.230 214.311 1.00 96.35  ? 12  C     C "O2'" 1 
ATOM   111  C "C1'" . C     A 1 6   ? 199.217 238.135 212.102 1.00 91.83  ? 12  C     C "C1'" 1 
ATOM   112  N N1    . C     A 1 6   ? 199.093 237.560 210.736 1.00 88.46  ? 12  C     C N1    1 
ATOM   113  C C2    . C     A 1 6   ? 200.169 237.606 209.842 1.00 85.22  ? 12  C     C C2    1 
ATOM   114  O O2    . C     A 1 6   ? 201.238 238.115 210.207 1.00 83.29  ? 12  C     C O2    1 
ATOM   115  N N3    . C     A 1 6   ? 200.017 237.081 208.602 1.00 81.45  ? 12  C     C N3    1 
ATOM   116  C C4    . C     A 1 6   ? 198.853 236.535 208.230 1.00 79.34  ? 12  C     C C4    1 
ATOM   117  N N4    . C     A 1 6   ? 198.763 236.039 207.005 1.00 74.70  ? 12  C     C N4    1 
ATOM   118  C C5    . C     A 1 6   ? 197.747 236.486 209.119 1.00 80.85  ? 12  C     C C5    1 
ATOM   119  C C6    . C     A 1 6   ? 197.909 237.007 210.344 1.00 85.86  ? 12  C     C C6    1 
ATOM   120  O OP3   . U     B 1 1   ? 186.452 212.641 219.972 1.00 62.81  ? 1   U     D OP3   1 
ATOM   121  P P     . U     B 1 1   ? 186.438 213.624 221.076 1.00 62.64  ? 1   U     D P     1 
ATOM   122  O OP1   . U     B 1 1   ? 186.453 214.977 220.473 1.00 61.22  ? 1   U     D OP1   1 
ATOM   123  O OP2   . U     B 1 1   ? 187.517 213.256 222.023 1.00 59.19  ? 1   U     D OP2   1 
ATOM   124  O "O5'" . U     B 1 1   ? 185.058 213.484 221.856 1.00 59.73  ? 1   U     D "O5'" 1 
ATOM   125  C "C5'" . U     B 1 1   ? 184.258 214.628 222.135 1.00 56.87  ? 1   U     D "C5'" 1 
ATOM   126  C "C4'" . U     B 1 1   ? 183.086 214.298 223.027 1.00 54.74  ? 1   U     D "C4'" 1 
ATOM   127  O "O4'" . U     B 1 1   ? 182.180 213.408 222.321 1.00 54.50  ? 1   U     D "O4'" 1 
ATOM   128  C "C3'" . U     B 1 1   ? 183.431 213.602 224.343 1.00 54.37  ? 1   U     D "C3'" 1 
ATOM   129  O "O3'" . U     B 1 1   ? 182.531 214.039 225.361 1.00 54.18  ? 1   U     D "O3'" 1 
ATOM   130  C "C2'" . U     B 1 1   ? 183.159 212.136 224.027 1.00 56.01  ? 1   U     D "C2'" 1 
ATOM   131  O "O2'" . U     B 1 1   ? 182.871 211.338 225.156 1.00 57.81  ? 1   U     D "O2'" 1 
ATOM   132  C "C1'" . U     B 1 1   ? 181.960 212.243 223.092 1.00 54.76  ? 1   U     D "C1'" 1 
ATOM   133  N N1    . U     B 1 1   ? 181.800 211.105 222.178 1.00 55.15  ? 1   U     D N1    1 
ATOM   134  C C2    . U     B 1 1   ? 180.804 210.201 222.474 1.00 57.34  ? 1   U     D C2    1 
ATOM   135  O O2    . U     B 1 1   ? 180.080 210.318 223.446 1.00 58.09  ? 1   U     D O2    1 
ATOM   136  N N3    . U     B 1 1   ? 180.687 209.153 221.597 1.00 57.23  ? 1   U     D N3    1 
ATOM   137  C C4    . U     B 1 1   ? 181.449 208.926 220.475 1.00 56.04  ? 1   U     D C4    1 
ATOM   138  O O4    . U     B 1 1   ? 181.218 207.935 219.784 1.00 56.21  ? 1   U     D O4    1 
ATOM   139  C C5    . U     B 1 1   ? 182.459 209.908 220.233 1.00 55.65  ? 1   U     D C5    1 
ATOM   140  C C6    . U     B 1 1   ? 182.597 210.939 221.071 1.00 56.35  ? 1   U     D C6    1 
ATOM   141  P P     . C     B 1 2   ? 182.866 215.345 226.235 1.00 51.73  ? 2   C     D P     1 
ATOM   142  O OP1   . C     B 1 2   ? 181.658 216.204 226.242 1.00 50.93  ? 2   C     D OP1   1 
ATOM   143  O OP2   . C     B 1 2   ? 184.159 215.901 225.768 1.00 55.05  ? 2   C     D OP2   1 
ATOM   144  O "O5'" . C     B 1 2   ? 183.067 214.792 227.714 1.00 54.35  ? 2   C     D "O5'" 1 
ATOM   145  C "C5'" . C     B 1 2   ? 183.613 213.504 227.953 1.00 52.87  ? 2   C     D "C5'" 1 
ATOM   146  C "C4'" . C     B 1 2   ? 184.332 213.448 229.277 1.00 53.92  ? 2   C     D "C4'" 1 
ATOM   147  O "O4'" . C     B 1 2   ? 185.722 213.102 229.065 1.00 55.63  ? 2   C     D "O4'" 1 
ATOM   148  C "C3'" . C     B 1 2   ? 184.387 214.750 230.061 1.00 54.27  ? 2   C     D "C3'" 1 
ATOM   149  O "O3'" . C     B 1 2   ? 183.207 214.986 230.806 1.00 54.18  ? 2   C     D "O3'" 1 
ATOM   150  C "C2'" . C     B 1 2   ? 185.621 214.570 230.934 1.00 54.91  ? 2   C     D "C2'" 1 
ATOM   151  O "O2'" . C     B 1 2   ? 185.313 213.793 232.082 1.00 56.53  ? 2   C     D "O2'" 1 
ATOM   152  C "C1'" . C     B 1 2   ? 186.530 213.744 230.026 1.00 55.10  ? 2   C     D "C1'" 1 
ATOM   153  N N1    . C     B 1 2   ? 187.588 214.545 229.357 1.00 53.97  ? 2   C     D N1    1 
ATOM   154  C C2    . C     B 1 2   ? 187.482 215.042 228.048 1.00 53.32  ? 2   C     D C2    1 
ATOM   155  O O2    . C     B 1 2   ? 186.466 214.852 227.366 1.00 54.21  ? 2   C     D O2    1 
ATOM   156  N N3    . C     B 1 2   ? 188.509 215.747 227.526 1.00 52.23  ? 2   C     D N3    1 
ATOM   157  C C4    . C     B 1 2   ? 189.610 215.968 228.237 1.00 51.81  ? 2   C     D C4    1 
ATOM   158  N N4    . C     B 1 2   ? 190.592 216.670 227.669 1.00 52.59  ? 2   C     D N4    1 
ATOM   159  C C5    . C     B 1 2   ? 189.754 215.478 229.560 1.00 52.70  ? 2   C     D C5    1 
ATOM   160  C C6    . C     B 1 2   ? 188.733 214.781 230.065 1.00 53.76  ? 2   C     D C6    1 
ATOM   161  P P     . U     B 1 3   ? 182.791 216.480 231.221 1.00 57.51  ? 3   U     D P     1 
ATOM   162  O OP1   . U     B 1 3   ? 181.464 216.401 231.875 1.00 53.94  ? 3   U     D OP1   1 
ATOM   163  O OP2   . U     B 1 3   ? 182.989 217.372 230.052 1.00 58.52  ? 3   U     D OP2   1 
ATOM   164  O "O5'" . U     B 1 3   ? 183.851 216.883 232.337 1.00 55.72  ? 3   U     D "O5'" 1 
ATOM   165  C "C5'" . U     B 1 3   ? 183.825 216.269 233.616 1.00 53.91  ? 3   U     D "C5'" 1 
ATOM   166  C "C4'" . U     B 1 3   ? 185.050 216.613 234.425 1.00 53.70  ? 3   U     D "C4'" 1 
ATOM   167  O "O4'" . U     B 1 3   ? 186.241 216.112 233.756 1.00 51.55  ? 3   U     D "O4'" 1 
ATOM   168  C "C3'" . U     B 1 3   ? 185.350 218.090 234.606 1.00 54.26  ? 3   U     D "C3'" 1 
ATOM   169  O "O3'" . U     B 1 3   ? 184.480 218.789 235.497 1.00 54.20  ? 3   U     D "O3'" 1 
ATOM   170  C "C2'" . U     B 1 3   ? 186.837 218.073 234.951 1.00 53.46  ? 3   U     D "C2'" 1 
ATOM   171  O "O2'" . U     B 1 3   ? 187.069 217.612 236.272 1.00 53.65  ? 3   U     D "O2'" 1 
ATOM   172  C "C1'" . U     B 1 3   ? 187.330 216.982 234.003 1.00 51.51  ? 3   U     D "C1'" 1 
ATOM   173  N N1    . U     B 1 3   ? 187.808 217.554 232.724 1.00 52.40  ? 3   U     D N1    1 
ATOM   174  C C2    . U     B 1 3   ? 189.098 218.041 232.708 1.00 52.60  ? 3   U     D C2    1 
ATOM   175  O O2    . U     B 1 3   ? 189.829 217.997 233.681 1.00 53.38  ? 3   U     D O2    1 
ATOM   176  N N3    . U     B 1 3   ? 189.510 218.574 231.514 1.00 52.68  ? 3   U     D N3    1 
ATOM   177  C C4    . U     B 1 3   ? 188.772 218.675 230.356 1.00 53.37  ? 3   U     D C4    1 
ATOM   178  O O4    . U     B 1 3   ? 189.283 219.182 229.358 1.00 56.31  ? 3   U     D O4    1 
ATOM   179  C C5    . U     B 1 3   ? 187.444 218.156 230.451 1.00 52.25  ? 3   U     D C5    1 
ATOM   180  C C6    . U     B 1 3   ? 187.017 217.632 231.603 1.00 53.11  ? 3   U     D C6    1 
ATOM   181  P P     . C     B 1 4   ? 184.573 218.669 237.098 1.00 58.15  ? 4   C     D P     1 
ATOM   182  O OP1   . C     B 1 4   ? 184.873 217.266 237.474 1.00 62.45  ? 4   C     D OP1   1 
ATOM   183  O OP2   . C     B 1 4   ? 183.372 219.332 237.664 1.00 56.89  ? 4   C     D OP2   1 
ATOM   184  O "O5'" . C     B 1 4   ? 185.836 219.559 237.481 1.00 53.37  ? 4   C     D "O5'" 1 
ATOM   185  C "C5'" . C     B 1 4   ? 186.450 219.423 238.752 1.00 55.37  ? 4   C     D "C5'" 1 
ATOM   186  C "C4'" . C     B 1 4   ? 187.765 220.157 238.828 1.00 54.18  ? 4   C     D "C4'" 1 
ATOM   187  O "O4'" . C     B 1 4   ? 188.616 219.788 237.715 1.00 52.27  ? 4   C     D "O4'" 1 
ATOM   188  C "C3'" . C     B 1 4   ? 187.703 221.669 238.743 1.00 53.60  ? 4   C     D "C3'" 1 
ATOM   189  O "O3'" . C     B 1 4   ? 187.287 222.275 239.952 1.00 52.22  ? 4   C     D "O3'" 1 
ATOM   190  C "C2'" . C     B 1 4   ? 189.125 222.029 238.331 1.00 53.63  ? 4   C     D "C2'" 1 
ATOM   191  O "O2'" . C     B 1 4   ? 189.995 221.985 239.451 1.00 52.76  ? 4   C     D "O2'" 1 
ATOM   192  C "C1'" . C     B 1 4   ? 189.477 220.864 237.401 1.00 53.69  ? 4   C     D "C1'" 1 
ATOM   193  N N1    . C     B 1 4   ? 189.327 221.218 235.971 1.00 54.02  ? 4   C     D N1    1 
ATOM   194  C C2    . C     B 1 4   ? 190.483 221.530 235.256 1.00 52.11  ? 4   C     D C2    1 
ATOM   195  O O2    . C     B 1 4   ? 191.574 221.486 235.843 1.00 51.39  ? 4   C     D O2    1 
ATOM   196  N N3    . C     B 1 4   ? 190.390 221.860 233.950 1.00 51.44  ? 4   C     D N3    1 
ATOM   197  C C4    . C     B 1 4   ? 189.199 221.895 233.358 1.00 53.12  ? 4   C     D C4    1 
ATOM   198  N N4    . C     B 1 4   ? 189.151 222.228 232.067 1.00 54.91  ? 4   C     D N4    1 
ATOM   199  C C5    . C     B 1 4   ? 188.000 221.588 234.060 1.00 53.29  ? 4   C     D C5    1 
ATOM   200  C C6    . C     B 1 4   ? 188.111 221.262 235.353 1.00 54.37  ? 4   C     D C6    1 
ATOM   201  P P     . U     B 1 5   ? 186.445 223.640 239.921 1.00 55.28  ? 5   U     D P     1 
ATOM   202  O OP1   . U     B 1 5   ? 185.742 223.775 241.219 1.00 52.52  ? 5   U     D OP1   1 
ATOM   203  O OP2   . U     B 1 5   ? 185.679 223.690 238.653 1.00 56.89  ? 5   U     D OP2   1 
ATOM   204  O "O5'" . U     B 1 5   ? 187.564 224.766 239.870 1.00 54.28  ? 5   U     D "O5'" 1 
ATOM   205  C "C5'" . U     B 1 5   ? 188.639 224.739 240.791 1.00 53.72  ? 5   U     D "C5'" 1 
ATOM   206  C "C4'" . U     B 1 5   ? 189.890 225.338 240.207 1.00 54.17  ? 5   U     D "C4'" 1 
ATOM   207  O "O4'" . U     B 1 5   ? 189.683 226.753 239.976 1.00 54.29  ? 5   U     D "O4'" 1 
ATOM   208  C "C3'" . U     B 1 5   ? 191.114 225.271 241.106 1.00 55.08  ? 5   U     D "C3'" 1 
ATOM   209  O "O3'" . U     B 1 5   ? 191.796 224.037 240.982 1.00 55.77  ? 5   U     D "O3'" 1 
ATOM   210  C "C2'" . U     B 1 5   ? 191.942 226.467 240.656 1.00 55.12  ? 5   U     D "C2'" 1 
ATOM   211  O "O2'" . U     B 1 5   ? 192.685 226.149 239.489 1.00 54.99  ? 5   U     D "O2'" 1 
ATOM   212  C "C1'" . U     B 1 5   ? 190.857 227.472 240.272 1.00 54.64  ? 5   U     D "C1'" 1 
ATOM   213  N N1    . U     B 1 5   ? 190.540 228.444 241.344 1.00 54.87  ? 5   U     D N1    1 
ATOM   214  C C2    . U     B 1 5   ? 191.476 229.390 241.714 1.00 55.31  ? 5   U     D C2    1 
ATOM   215  O O2    . U     B 1 5   ? 192.590 229.458 241.229 1.00 56.45  ? 5   U     D O2    1 
ATOM   216  N N3    . U     B 1 5   ? 191.068 230.254 242.697 1.00 53.14  ? 5   U     D N3    1 
ATOM   217  C C4    . U     B 1 5   ? 189.842 230.281 243.323 1.00 54.26  ? 5   U     D C4    1 
ATOM   218  O O4    . U     B 1 5   ? 189.623 231.125 244.189 1.00 55.55  ? 5   U     D O4    1 
ATOM   219  C C5    . U     B 1 5   ? 188.922 229.285 242.875 1.00 53.38  ? 5   U     D C5    1 
ATOM   220  C C6    . U     B 1 5   ? 189.295 228.429 241.922 1.00 53.41  ? 5   U     D C6    1 
ATOM   221  P P     . C     B 1 6   ? 192.239 223.218 242.287 1.00 57.84  ? 6   C     D P     1 
ATOM   222  O OP1   . C     B 1 6   ? 192.806 221.924 241.835 1.00 56.35  ? 6   C     D OP1   1 
ATOM   223  O OP2   . C     B 1 6   ? 191.111 223.225 243.249 1.00 57.15  ? 6   C     D OP2   1 
ATOM   224  O "O5'" . C     B 1 6   ? 193.422 224.091 242.895 1.00 56.71  ? 6   C     D "O5'" 1 
ATOM   225  C "C5'" . C     B 1 6   ? 194.639 224.263 242.188 1.00 54.38  ? 6   C     D "C5'" 1 
ATOM   226  C "C4'" . C     B 1 6   ? 195.512 225.294 242.853 1.00 54.28  ? 6   C     D "C4'" 1 
ATOM   227  O "O4'" . C     B 1 6   ? 194.852 226.584 242.805 1.00 53.54  ? 6   C     D "O4'" 1 
ATOM   228  C "C3'" . C     B 1 6   ? 195.786 225.074 244.333 1.00 54.10  ? 6   C     D "C3'" 1 
ATOM   229  O "O3'" . C     B 1 6   ? 196.831 224.148 244.573 1.00 47.59  ? 6   C     D "O3'" 1 
ATOM   230  C "C2'" . C     B 1 6   ? 196.091 226.481 244.829 1.00 56.03  ? 6   C     D "C2'" 1 
ATOM   231  O "O2'" . C     B 1 6   ? 197.422 226.851 244.497 1.00 59.42  ? 6   C     D "O2'" 1 
ATOM   232  C "C1'" . C     B 1 6   ? 195.134 227.315 243.978 1.00 53.97  ? 6   C     D "C1'" 1 
ATOM   233  N N1    . C     B 1 6   ? 193.861 227.600 244.676 1.00 53.75  ? 6   C     D N1    1 
ATOM   234  C C2    . C     B 1 6   ? 193.807 228.708 245.516 1.00 54.67  ? 6   C     D C2    1 
ATOM   235  O O2    . C     B 1 6   ? 194.824 229.403 245.644 1.00 55.61  ? 6   C     D O2    1 
ATOM   236  N N3    . C     B 1 6   ? 192.656 228.992 246.164 1.00 54.00  ? 6   C     D N3    1 
ATOM   237  C C4    . C     B 1 6   ? 191.588 228.217 245.994 1.00 52.80  ? 6   C     D C4    1 
ATOM   238  N N4    . C     B 1 6   ? 190.474 228.536 246.655 1.00 53.57  ? 6   C     D N4    1 
ATOM   239  C C5    . C     B 1 6   ? 191.611 227.080 245.141 1.00 53.09  ? 6   C     D C5    1 
ATOM   240  C C6    . C     B 1 6   ? 192.759 226.811 244.507 1.00 53.69  ? 6   C     D C6    1 
ATOM   241  N N     . THR   C 2 3   ? 203.948 255.071 211.054 1.00 82.04  ? 15  THR   A N     1 
ATOM   242  C CA    . THR   C 2 3   ? 203.847 254.080 209.990 1.00 79.13  ? 15  THR   A CA    1 
ATOM   243  C C     . THR   C 2 3   ? 204.467 254.607 208.700 1.00 83.13  ? 15  THR   A C     1 
ATOM   244  O O     . THR   C 2 3   ? 205.012 255.709 208.671 1.00 92.81  ? 15  THR   A O     1 
ATOM   245  C CB    . THR   C 2 3   ? 202.384 253.680 209.733 1.00 81.75  ? 15  THR   A CB    1 
ATOM   246  O OG1   . THR   C 2 3   ? 202.341 252.588 208.805 1.00 85.24  ? 15  THR   A OG1   1 
ATOM   247  C CG2   . THR   C 2 3   ? 201.599 254.853 209.170 1.00 83.20  ? 15  THR   A CG2   1 
ATOM   248  N N     . ASP   C 2 4   ? 204.379 253.818 207.636 1.00 75.19  ? 16  ASP   A N     1 
ATOM   249  C CA    . ASP   C 2 4   ? 204.983 254.176 206.357 1.00 69.48  ? 16  ASP   A CA    1 
ATOM   250  C C     . ASP   C 2 4   ? 204.246 253.415 205.258 1.00 65.58  ? 16  ASP   A C     1 
ATOM   251  O O     . ASP   C 2 4   ? 203.140 252.907 205.480 1.00 68.60  ? 16  ASP   A O     1 
ATOM   252  C CB    . ASP   C 2 4   ? 206.495 253.895 206.369 1.00 67.63  ? 16  ASP   A CB    1 
ATOM   253  C CG    . ASP   C 2 4   ? 206.815 252.447 206.654 1.00 73.52  ? 16  ASP   A CG    1 
ATOM   254  O OD1   . ASP   C 2 4   ? 206.667 251.612 205.738 1.00 74.73  ? 16  ASP   A OD1   1 
ATOM   255  O OD2   . ASP   C 2 4   ? 207.223 252.146 207.793 1.00 79.68  ? 16  ASP   A OD2   1 
ATOM   256  N N     . GLY   C 2 5   ? 204.850 253.347 204.073 1.00 59.21  ? 17  GLY   A N     1 
ATOM   257  C CA    . GLY   C 2 5   ? 204.272 252.653 202.935 1.00 53.92  ? 17  GLY   A CA    1 
ATOM   258  C C     . GLY   C 2 5   ? 203.871 251.212 203.188 1.00 60.70  ? 17  GLY   A C     1 
ATOM   259  O O     . GLY   C 2 5   ? 203.280 250.569 202.316 1.00 59.90  ? 17  GLY   A O     1 
ATOM   260  N N     . GLU   C 2 6   ? 204.187 250.691 204.377 1.00 66.61  ? 18  GLU   A N     1 
ATOM   261  C CA    . GLU   C 2 6   ? 203.700 249.395 204.833 1.00 57.80  ? 18  GLU   A CA    1 
ATOM   262  C C     . GLU   C 2 6   ? 202.204 249.396 205.130 1.00 58.54  ? 18  GLU   A C     1 
ATOM   263  O O     . GLU   C 2 6   ? 201.694 248.395 205.646 1.00 58.96  ? 18  GLU   A O     1 
ATOM   264  C CB    . GLU   C 2 6   ? 204.475 248.956 206.077 1.00 57.85  ? 18  GLU   A CB    1 
ATOM   265  C CG    . GLU   C 2 6   ? 204.003 249.607 207.368 1.00 61.49  ? 18  GLU   A CG    1 
ATOM   266  C CD    . GLU   C 2 6   ? 205.132 249.859 208.344 1.00 69.51  ? 18  GLU   A CD    1 
ATOM   267  O OE1   . GLU   C 2 6   ? 206.083 249.053 208.381 1.00 64.60  ? 18  GLU   A OE1   1 
ATOM   268  O OE2   . GLU   C 2 6   ? 205.062 250.863 209.083 1.00 78.67  ? 18  GLU   A OE2   1 
ATOM   269  N N     . ARG   C 2 7   ? 201.499 250.490 204.828 1.00 60.99  ? 19  ARG   A N     1 
ATOM   270  C CA    . ARG   C 2 7   ? 200.050 250.521 204.995 1.00 55.17  ? 19  ARG   A CA    1 
ATOM   271  C C     . ARG   C 2 7   ? 199.370 249.449 204.157 1.00 56.45  ? 19  ARG   A C     1 
ATOM   272  O O     . ARG   C 2 7   ? 198.428 248.795 204.619 1.00 57.99  ? 19  ARG   A O     1 
ATOM   273  C CB    . ARG   C 2 7   ? 199.507 251.898 204.615 1.00 55.56  ? 19  ARG   A CB    1 
ATOM   274  C CG    . ARG   C 2 7   ? 199.894 253.023 205.544 1.00 56.52  ? 19  ARG   A CG    1 
ATOM   275  C CD    . ARG   C 2 7   ? 198.783 254.048 205.589 1.00 57.47  ? 19  ARG   A CD    1 
ATOM   276  N NE    . ARG   C 2 7   ? 198.666 254.755 204.319 1.00 55.85  ? 19  ARG   A NE    1 
ATOM   277  C CZ    . ARG   C 2 7   ? 197.922 255.833 204.126 1.00 61.75  ? 19  ARG   A CZ    1 
ATOM   278  N NH1   . ARG   C 2 7   ? 197.197 256.356 205.101 1.00 67.37  ? 19  ARG   A NH1   1 
ATOM   279  N NH2   . ARG   C 2 7   ? 197.901 256.400 202.925 1.00 57.86  ? 19  ARG   A NH2   1 
ATOM   280  N N     . GLN   C 2 8   ? 199.822 249.264 202.914 1.00 55.62  ? 20  GLN   A N     1 
ATOM   281  C CA    . GLN   C 2 8   ? 199.239 248.237 202.056 1.00 56.92  ? 20  GLN   A CA    1 
ATOM   282  C C     . GLN   C 2 8   ? 199.411 246.855 202.671 1.00 57.41  ? 20  GLN   A C     1 
ATOM   283  O O     . GLN   C 2 8   ? 198.480 246.039 202.675 1.00 57.64  ? 20  GLN   A O     1 
ATOM   284  C CB    . GLN   C 2 8   ? 199.875 248.295 200.666 1.00 58.07  ? 20  GLN   A CB    1 
ATOM   285  C CG    . GLN   C 2 8   ? 199.075 247.609 199.561 1.00 61.78  ? 20  GLN   A CG    1 
ATOM   286  C CD    . GLN   C 2 8   ? 197.614 248.022 199.514 1.00 74.42  ? 20  GLN   A CD    1 
ATOM   287  O OE1   . GLN   C 2 8   ? 197.241 249.112 199.952 1.00 76.38  ? 20  GLN   A OE1   1 
ATOM   288  N NE2   . GLN   C 2 8   ? 196.774 247.143 198.981 1.00 75.48  ? 20  GLN   A NE2   1 
ATOM   289  N N     . ASN   C 2 9   ? 200.603 246.577 203.204 1.00 53.79  ? 21  ASN   A N     1 
ATOM   290  C CA    . ASN   C 2 9   ? 200.819 245.330 203.923 1.00 50.94  ? 21  ASN   A CA    1 
ATOM   291  C C     . ASN   C 2 9   ? 199.930 245.243 205.154 1.00 52.74  ? 21  ASN   A C     1 
ATOM   292  O O     . ASN   C 2 9   ? 199.411 244.168 205.468 1.00 58.57  ? 21  ASN   A O     1 
ATOM   293  C CB    . ASN   C 2 9   ? 202.291 245.201 204.313 1.00 52.11  ? 21  ASN   A CB    1 
ATOM   294  C CG    . ASN   C 2 9   ? 202.693 243.772 204.605 1.00 62.65  ? 21  ASN   A CG    1 
ATOM   295  O OD1   . ASN   C 2 9   ? 201.900 242.846 204.445 1.00 68.95  ? 21  ASN   A OD1   1 
ATOM   296  N ND2   . ASN   C 2 9   ? 203.936 243.585 205.033 1.00 61.12  ? 21  ASN   A ND2   1 
ATOM   297  N N     . ALA   C 2 10  ? 199.727 246.362 205.850 1.00 50.41  ? 22  ALA   A N     1 
ATOM   298  C CA    . ALA   C 2 10  ? 198.860 246.380 207.020 1.00 46.30  ? 22  ALA   A CA    1 
ATOM   299  C C     . ALA   C 2 10  ? 197.387 246.231 206.668 1.00 47.56  ? 22  ALA   A C     1 
ATOM   300  O O     . ALA   C 2 10  ? 196.602 245.828 207.531 1.00 47.15  ? 22  ALA   A O     1 
ATOM   301  C CB    . ALA   C 2 10  ? 199.068 247.673 207.809 1.00 46.31  ? 22  ALA   A CB    1 
ATOM   302  N N     . THR   C 2 11  ? 196.997 246.535 205.432 1.00 51.04  ? 23  THR   A N     1 
ATOM   303  C CA    . THR   C 2 11  ? 195.624 246.332 204.990 1.00 50.36  ? 23  THR   A CA    1 
ATOM   304  C C     . THR   C 2 11  ? 195.381 244.932 204.446 1.00 51.40  ? 23  THR   A C     1 
ATOM   305  O O     . THR   C 2 11  ? 194.280 244.396 204.614 1.00 52.03  ? 23  THR   A O     1 
ATOM   306  C CB    . THR   C 2 11  ? 195.251 247.364 203.920 1.00 51.78  ? 23  THR   A CB    1 
ATOM   307  O OG1   . THR   C 2 11  ? 195.738 248.653 204.308 1.00 52.81  ? 23  THR   A OG1   1 
ATOM   308  C CG2   . THR   C 2 11  ? 193.744 247.440 203.754 1.00 51.09  ? 23  THR   A CG2   1 
ATOM   309  N N     . GLU   C 2 12  ? 196.385 244.320 203.817 1.00 51.80  ? 24  GLU   A N     1 
ATOM   310  C CA    . GLU   C 2 12  ? 196.235 242.937 203.372 1.00 51.10  ? 24  GLU   A CA    1 
ATOM   311  C C     . GLU   C 2 12  ? 196.066 241.989 204.556 1.00 50.78  ? 24  GLU   A C     1 
ATOM   312  O O     . GLU   C 2 12  ? 195.246 241.063 204.508 1.00 50.33  ? 24  GLU   A O     1 
ATOM   313  C CB    . GLU   C 2 12  ? 197.432 242.530 202.515 1.00 54.20  ? 24  GLU   A CB    1 
ATOM   314  C CG    . GLU   C 2 12  ? 197.479 243.223 201.165 1.00 53.92  ? 24  GLU   A CG    1 
ATOM   315  C CD    . GLU   C 2 12  ? 198.697 242.842 200.353 1.00 65.07  ? 24  GLU   A CD    1 
ATOM   316  O OE1   . GLU   C 2 12  ? 199.588 242.160 200.900 1.00 73.24  ? 24  GLU   A OE1   1 
ATOM   317  O OE2   . GLU   C 2 12  ? 198.765 243.224 199.167 1.00 69.80  ? 24  GLU   A OE2   1 
ATOM   318  N N     . ILE   C 2 13  ? 196.837 242.199 205.626 1.00 48.29  ? 25  ILE   A N     1 
ATOM   319  C CA    . ILE   C 2 13  ? 196.686 241.380 206.826 1.00 48.26  ? 25  ILE   A CA    1 
ATOM   320  C C     . ILE   C 2 13  ? 195.301 241.568 207.427 1.00 48.38  ? 25  ILE   A C     1 
ATOM   321  O O     . ILE   C 2 13  ? 194.670 240.610 207.893 1.00 51.59  ? 25  ILE   A O     1 
ATOM   322  C CB    . ILE   C 2 13  ? 197.795 241.706 207.845 1.00 50.51  ? 25  ILE   A CB    1 
ATOM   323  C CG1   . ILE   C 2 13  ? 199.173 241.578 207.199 1.00 52.08  ? 25  ILE   A CG1   1 
ATOM   324  C CG2   . ILE   C 2 13  ? 197.696 240.797 209.055 1.00 54.11  ? 25  ILE   A CG2   1 
ATOM   325  C CD1   . ILE   C 2 13  ? 199.516 240.170 206.779 1.00 57.09  ? 25  ILE   A CD1   1 
ATOM   326  N N     . ARG   C 2 14  ? 194.812 242.811 207.440 1.00 45.57  ? 26  ARG   A N     1 
ATOM   327  C CA    . ARG   C 2 14  ? 193.467 243.076 207.937 1.00 45.08  ? 26  ARG   A CA    1 
ATOM   328  C C     . ARG   C 2 14  ? 192.424 242.333 207.114 1.00 47.59  ? 26  ARG   A C     1 
ATOM   329  O O     . ARG   C 2 14  ? 191.493 241.739 207.667 1.00 46.84  ? 26  ARG   A O     1 
ATOM   330  C CB    . ARG   C 2 14  ? 193.191 244.578 207.920 1.00 40.85  ? 26  ARG   A CB    1 
ATOM   331  C CG    . ARG   C 2 14  ? 193.669 245.313 209.152 1.00 41.63  ? 26  ARG   A CG    1 
ATOM   332  C CD    . ARG   C 2 14  ? 193.209 246.756 209.138 1.00 40.59  ? 26  ARG   A CD    1 
ATOM   333  N NE    . ARG   C 2 14  ? 192.299 247.042 210.240 1.00 41.64  ? 26  ARG   A NE    1 
ATOM   334  C CZ    . ARG   C 2 14  ? 190.983 247.134 210.117 1.00 43.17  ? 26  ARG   A CZ    1 
ATOM   335  N NH1   . ARG   C 2 14  ? 190.388 246.985 208.946 1.00 42.91  ? 26  ARG   A NH1   1 
ATOM   336  N NH2   . ARG   C 2 14  ? 190.247 247.382 211.195 1.00 42.29  ? 26  ARG   A NH2   1 
ATOM   337  N N     . ALA   C 2 15  ? 192.572 242.345 205.789 1.00 48.25  ? 27  ALA   A N     1 
ATOM   338  C CA    . ALA   C 2 15  ? 191.637 241.624 204.934 1.00 46.29  ? 27  ALA   A CA    1 
ATOM   339  C C     . ALA   C 2 15  ? 191.685 240.122 205.196 1.00 48.48  ? 27  ALA   A C     1 
ATOM   340  O O     . ALA   C 2 15  ? 190.644 239.458 205.234 1.00 49.81  ? 27  ALA   A O     1 
ATOM   341  C CB    . ALA   C 2 15  ? 191.932 241.923 203.465 1.00 46.50  ? 27  ALA   A CB    1 
ATOM   342  N N     . SER   C 2 16  ? 192.886 239.568 205.378 1.00 47.36  ? 28  SER   A N     1 
ATOM   343  C CA    . SER   C 2 16  ? 193.009 238.129 205.598 1.00 46.28  ? 28  SER   A CA    1 
ATOM   344  C C     . SER   C 2 16  ? 192.390 237.712 206.930 1.00 48.31  ? 28  SER   A C     1 
ATOM   345  O O     . SER   C 2 16  ? 191.669 236.705 207.007 1.00 47.48  ? 28  SER   A O     1 
ATOM   346  C CB    . SER   C 2 16  ? 194.479 237.716 205.528 1.00 45.35  ? 28  SER   A CB    1 
ATOM   347  O OG    . SER   C 2 16  ? 195.205 238.232 206.629 1.00 55.67  ? 28  SER   A OG    1 
ATOM   348  N N     . VAL   C 2 17  ? 192.650 238.476 207.993 1.00 47.79  ? 29  VAL   A N     1 
ATOM   349  C CA    . VAL   C 2 17  ? 192.050 238.125 209.275 1.00 45.67  ? 29  VAL   A CA    1 
ATOM   350  C C     . VAL   C 2 17  ? 190.543 238.352 209.241 1.00 46.03  ? 29  VAL   A C     1 
ATOM   351  O O     . VAL   C 2 17  ? 189.784 237.606 209.872 1.00 48.28  ? 29  VAL   A O     1 
ATOM   352  C CB    . VAL   C 2 17  ? 192.726 238.885 210.433 1.00 45.30  ? 29  VAL   A CB    1 
ATOM   353  C CG1   . VAL   C 2 17  ? 194.214 238.586 210.459 1.00 50.67  ? 29  VAL   A CG1   1 
ATOM   354  C CG2   . VAL   C 2 17  ? 192.493 240.364 210.314 1.00 46.65  ? 29  VAL   A CG2   1 
ATOM   355  N N     . GLY   C 2 18  ? 190.077 239.353 208.492 1.00 44.56  ? 30  GLY   A N     1 
ATOM   356  C CA    . GLY   C 2 18  ? 188.646 239.524 208.319 1.00 45.66  ? 30  GLY   A CA    1 
ATOM   357  C C     . GLY   C 2 18  ? 188.006 238.351 207.603 1.00 45.79  ? 30  GLY   A C     1 
ATOM   358  O O     . GLY   C 2 18  ? 186.906 237.925 207.952 1.00 49.61  ? 30  GLY   A O     1 
ATOM   359  N N     . LYS   C 2 19  ? 188.687 237.811 206.592 1.00 45.60  ? 31  LYS   A N     1 
ATOM   360  C CA    . LYS   C 2 19  ? 188.129 236.663 205.889 1.00 46.66  ? 31  LYS   A CA    1 
ATOM   361  C C     . LYS   C 2 19  ? 188.133 235.419 206.769 1.00 44.96  ? 31  LYS   A C     1 
ATOM   362  O O     . LYS   C 2 19  ? 187.206 234.604 206.689 1.00 49.33  ? 31  LYS   A O     1 
ATOM   363  C CB    . LYS   C 2 19  ? 188.883 236.421 204.577 1.00 48.88  ? 31  LYS   A CB    1 
ATOM   364  C CG    . LYS   C 2 19  ? 189.975 235.374 204.627 1.00 53.53  ? 31  LYS   A CG    1 
ATOM   365  C CD    . LYS   C 2 19  ? 190.679 235.269 203.286 1.00 55.49  ? 31  LYS   A CD    1 
ATOM   366  C CE    . LYS   C 2 19  ? 189.725 234.808 202.201 1.00 48.49  ? 31  LYS   A CE    1 
ATOM   367  N NZ    . LYS   C 2 19  ? 190.445 234.451 200.951 1.00 51.37  ? 31  LYS   A NZ    1 
ATOM   368  N N     . MET   C 2 20  ? 189.134 235.269 207.639 1.00 43.38  ? 32  MET   A N     1 
ATOM   369  C CA    . MET   C 2 20  ? 189.104 234.147 208.575 1.00 42.91  ? 32  MET   A CA    1 
ATOM   370  C C     . MET   C 2 20  ? 187.974 234.308 209.594 1.00 43.76  ? 32  MET   A C     1 
ATOM   371  O O     . MET   C 2 20  ? 187.307 233.326 209.953 1.00 44.87  ? 32  MET   A O     1 
ATOM   372  C CB    . MET   C 2 20  ? 190.466 233.989 209.256 1.00 43.85  ? 32  MET   A CB    1 
ATOM   373  C CG    . MET   C 2 20  ? 190.569 234.514 210.675 1.00 44.42  ? 32  MET   A CG    1 
ATOM   374  S SD    . MET   C 2 20  ? 192.165 234.140 211.418 1.00 54.04  ? 32  MET   A SD    1 
ATOM   375  C CE    . MET   C 2 20  ? 191.931 234.813 213.056 1.00 47.78  ? 32  MET   A CE    1 
ATOM   376  N N     . ILE   C 2 21  ? 187.719 235.540 210.043 1.00 45.61  ? 33  ILE   A N     1 
ATOM   377  C CA    . ILE   C 2 21  ? 186.612 235.779 210.964 1.00 44.66  ? 33  ILE   A CA    1 
ATOM   378  C C     . ILE   C 2 21  ? 185.277 235.508 210.275 1.00 44.90  ? 33  ILE   A C     1 
ATOM   379  O O     . ILE   C 2 21  ? 184.355 234.941 210.874 1.00 43.37  ? 33  ILE   A O     1 
ATOM   380  C CB    . ILE   C 2 21  ? 186.685 237.210 211.526 1.00 44.26  ? 33  ILE   A CB    1 
ATOM   381  C CG1   . ILE   C 2 21  ? 187.924 237.386 212.407 1.00 42.84  ? 33  ILE   A CG1   1 
ATOM   382  C CG2   . ILE   C 2 21  ? 185.439 237.541 212.321 1.00 45.49  ? 33  ILE   A CG2   1 
ATOM   383  C CD1   . ILE   C 2 21  ? 188.292 236.165 213.219 1.00 47.96  ? 33  ILE   A CD1   1 
ATOM   384  N N     . ASP   C 2 22  ? 185.157 235.906 209.007 1.00 46.35  ? 34  ASP   A N     1 
ATOM   385  C CA    . ASP   C 2 22  ? 183.957 235.604 208.234 1.00 46.36  ? 34  ASP   A CA    1 
ATOM   386  C C     . ASP   C 2 22  ? 183.758 234.103 208.092 1.00 47.41  ? 34  ASP   A C     1 
ATOM   387  O O     . ASP   C 2 22  ? 182.632 233.603 208.199 1.00 47.68  ? 34  ASP   A O     1 
ATOM   388  C CB    . ASP   C 2 22  ? 184.046 236.257 206.855 1.00 45.26  ? 34  ASP   A CB    1 
ATOM   389  C CG    . ASP   C 2 22  ? 183.051 237.377 206.673 1.00 53.39  ? 34  ASP   A CG    1 
ATOM   390  O OD1   . ASP   C 2 22  ? 182.146 237.513 207.520 1.00 56.71  ? 34  ASP   A OD1   1 
ATOM   391  O OD2   . ASP   C 2 22  ? 183.170 238.119 205.678 1.00 56.90  ? 34  ASP   A OD2   1 
ATOM   392  N N     . GLY   C 2 23  ? 184.840 233.371 207.823 1.00 45.41  ? 35  GLY   A N     1 
ATOM   393  C CA    . GLY   C 2 23  ? 184.736 231.925 207.733 1.00 40.85  ? 35  GLY   A CA    1 
ATOM   394  C C     . GLY   C 2 23  ? 184.243 231.309 209.026 1.00 43.99  ? 35  GLY   A C     1 
ATOM   395  O O     . GLY   C 2 23  ? 183.349 230.460 209.023 1.00 48.45  ? 35  GLY   A O     1 
ATOM   396  N N     . ILE   C 2 24  ? 184.801 231.756 210.154 1.00 45.09  ? 36  ILE   A N     1 
ATOM   397  C CA    . ILE   C 2 24  ? 184.367 231.244 211.453 1.00 45.34  ? 36  ILE   A CA    1 
ATOM   398  C C     . ILE   C 2 24  ? 182.888 231.541 211.676 1.00 44.90  ? 36  ILE   A C     1 
ATOM   399  O O     . ILE   C 2 24  ? 182.112 230.669 212.089 1.00 42.77  ? 36  ILE   A O     1 
ATOM   400  C CB    . ILE   C 2 24  ? 185.235 231.836 212.577 1.00 42.14  ? 36  ILE   A CB    1 
ATOM   401  C CG1   . ILE   C 2 24  ? 186.678 231.356 212.450 1.00 44.33  ? 36  ILE   A CG1   1 
ATOM   402  C CG2   . ILE   C 2 24  ? 184.673 231.466 213.938 1.00 44.07  ? 36  ILE   A CG2   1 
ATOM   403  C CD1   . ILE   C 2 24  ? 187.606 231.953 213.476 1.00 41.65  ? 36  ILE   A CD1   1 
ATOM   404  N N     . GLY   C 2 25  ? 182.474 232.777 211.392 1.00 44.03  ? 37  GLY   A N     1 
ATOM   405  C CA    . GLY   C 2 25  ? 181.098 233.166 211.657 1.00 44.13  ? 37  GLY   A CA    1 
ATOM   406  C C     . GLY   C 2 25  ? 180.096 232.416 210.800 1.00 43.72  ? 37  GLY   A C     1 
ATOM   407  O O     . GLY   C 2 25  ? 179.069 231.941 211.292 1.00 45.32  ? 37  GLY   A O     1 
ATOM   408  N N     . ARG   C 2 26  ? 180.380 232.294 209.503 1.00 42.39  ? 38  ARG   A N     1 
ATOM   409  C CA    . ARG   C 2 26  ? 179.428 231.607 208.639 1.00 44.49  ? 38  ARG   A CA    1 
ATOM   410  C C     . ARG   C 2 26  ? 179.459 230.103 208.864 1.00 43.87  ? 38  ARG   A C     1 
ATOM   411  O O     . ARG   C 2 26  ? 178.436 229.433 208.681 1.00 45.39  ? 38  ARG   A O     1 
ATOM   412  C CB    . ARG   C 2 26  ? 179.682 231.960 207.175 1.00 44.18  ? 38  ARG   A CB    1 
ATOM   413  C CG    . ARG   C 2 26  ? 180.852 231.267 206.528 1.00 43.71  ? 38  ARG   A CG    1 
ATOM   414  C CD    . ARG   C 2 26  ? 180.767 231.439 205.028 1.00 44.98  ? 38  ARG   A CD    1 
ATOM   415  N NE    . ARG   C 2 26  ? 180.616 232.840 204.661 1.00 40.87  ? 38  ARG   A NE    1 
ATOM   416  C CZ    . ARG   C 2 26  ? 181.626 233.673 204.457 1.00 43.65  ? 38  ARG   A CZ    1 
ATOM   417  N NH1   . ARG   C 2 26  ? 182.882 233.274 204.568 1.00 45.10  ? 38  ARG   A NH1   1 
ATOM   418  N NH2   . ARG   C 2 26  ? 181.370 234.936 204.133 1.00 42.16  ? 38  ARG   A NH2   1 
ATOM   419  N N     . PHE   C 2 27  ? 180.595 229.556 209.304 1.00 43.13  ? 39  PHE   A N     1 
ATOM   420  C CA    . PHE   C 2 27  ? 180.605 228.168 209.740 1.00 44.37  ? 39  PHE   A CA    1 
ATOM   421  C C     . PHE   C 2 27  ? 179.706 227.972 210.951 1.00 43.97  ? 39  PHE   A C     1 
ATOM   422  O O     . PHE   C 2 27  ? 178.969 226.982 211.035 1.00 43.54  ? 39  PHE   A O     1 
ATOM   423  C CB    . PHE   C 2 27  ? 182.026 227.723 210.067 1.00 45.39  ? 39  PHE   A CB    1 
ATOM   424  C CG    . PHE   C 2 27  ? 182.087 226.401 210.759 1.00 46.46  ? 39  PHE   A CG    1 
ATOM   425  C CD1   . PHE   C 2 27  ? 182.096 225.230 210.029 1.00 46.27  ? 39  PHE   A CD1   1 
ATOM   426  C CD2   . PHE   C 2 27  ? 182.110 226.326 212.136 1.00 45.55  ? 39  PHE   A CD2   1 
ATOM   427  C CE1   . PHE   C 2 27  ? 182.142 224.012 210.658 1.00 42.32  ? 39  PHE   A CE1   1 
ATOM   428  C CE2   . PHE   C 2 27  ? 182.142 225.116 212.762 1.00 44.27  ? 39  PHE   A CE2   1 
ATOM   429  C CZ    . PHE   C 2 27  ? 182.168 223.954 212.023 1.00 40.14  ? 39  PHE   A CZ    1 
ATOM   430  N N     . TYR   C 2 28  ? 179.772 228.895 211.913 1.00 43.65  ? 40  TYR   A N     1 
ATOM   431  C CA    . TYR   C 2 28  ? 178.905 228.797 213.080 1.00 42.71  ? 40  TYR   A CA    1 
ATOM   432  C C     . TYR   C 2 28  ? 177.441 228.904 212.680 1.00 42.48  ? 40  TYR   A C     1 
ATOM   433  O O     . TYR   C 2 28  ? 176.587 228.201 213.228 1.00 45.86  ? 40  TYR   A O     1 
ATOM   434  C CB    . TYR   C 2 28  ? 179.263 229.876 214.100 1.00 42.96  ? 40  TYR   A CB    1 
ATOM   435  C CG    . TYR   C 2 28  ? 178.519 229.744 215.409 1.00 42.75  ? 40  TYR   A CG    1 
ATOM   436  C CD1   . TYR   C 2 28  ? 178.928 228.835 216.373 1.00 42.88  ? 40  TYR   A CD1   1 
ATOM   437  C CD2   . TYR   C 2 28  ? 177.407 230.526 215.679 1.00 43.32  ? 40  TYR   A CD2   1 
ATOM   438  C CE1   . TYR   C 2 28  ? 178.252 228.710 217.566 1.00 43.72  ? 40  TYR   A CE1   1 
ATOM   439  C CE2   . TYR   C 2 28  ? 176.727 230.409 216.872 1.00 41.58  ? 40  TYR   A CE2   1 
ATOM   440  C CZ    . TYR   C 2 28  ? 177.154 229.499 217.810 1.00 43.23  ? 40  TYR   A CZ    1 
ATOM   441  O OH    . TYR   C 2 28  ? 176.478 229.376 219.000 1.00 48.54  ? 40  TYR   A OH    1 
ATOM   442  N N     . ILE   C 2 29  ? 177.134 229.781 211.724 1.00 41.81  ? 41  ILE   A N     1 
ATOM   443  C CA    . ILE   C 2 29  ? 175.759 229.913 211.247 1.00 44.62  ? 41  ILE   A CA    1 
ATOM   444  C C     . ILE   C 2 29  ? 175.286 228.607 210.618 1.00 43.46  ? 41  ILE   A C     1 
ATOM   445  O O     . ILE   C 2 29  ? 174.180 228.120 210.895 1.00 40.10  ? 41  ILE   A O     1 
ATOM   446  C CB    . ILE   C 2 29  ? 175.649 231.085 210.256 1.00 43.67  ? 41  ILE   A CB    1 
ATOM   447  C CG1   . ILE   C 2 29  ? 175.621 232.418 211.003 1.00 40.42  ? 41  ILE   A CG1   1 
ATOM   448  C CG2   . ILE   C 2 29  ? 174.410 230.939 209.393 1.00 43.86  ? 41  ILE   A CG2   1 
ATOM   449  C CD1   . ILE   C 2 29  ? 175.366 233.600 210.108 1.00 40.93  ? 41  ILE   A CD1   1 
ATOM   450  N N     . GLN   C 2 30  ? 176.123 228.015 209.763 1.00 45.69  ? 42  GLN   A N     1 
ATOM   451  C CA    . GLN   C 2 30  ? 175.749 226.767 209.106 1.00 44.77  ? 42  GLN   A CA    1 
ATOM   452  C C     . GLN   C 2 30  ? 175.561 225.643 210.115 1.00 45.38  ? 42  GLN   A C     1 
ATOM   453  O O     . GLN   C 2 30  ? 174.620 224.850 210.001 1.00 50.92  ? 42  GLN   A O     1 
ATOM   454  C CB    . GLN   C 2 30  ? 176.800 226.384 208.068 1.00 43.71  ? 42  GLN   A CB    1 
ATOM   455  C CG    . GLN   C 2 30  ? 176.605 225.000 207.495 1.00 48.78  ? 42  GLN   A CG    1 
ATOM   456  C CD    . GLN   C 2 30  ? 176.890 224.947 206.016 1.00 58.56  ? 42  GLN   A CD    1 
ATOM   457  O OE1   . GLN   C 2 30  ? 177.714 225.703 205.505 1.00 61.34  ? 42  GLN   A OE1   1 
ATOM   458  N NE2   . GLN   C 2 30  ? 176.202 224.056 205.312 1.00 54.98  ? 42  GLN   A NE2   1 
ATOM   459  N N     . MET   C 2 31  ? 176.444 225.558 211.110 1.00 44.85  ? 43  MET   A N     1 
ATOM   460  C CA    . MET   C 2 31  ? 176.317 224.516 212.121 1.00 44.98  ? 43  MET   A CA    1 
ATOM   461  C C     . MET   C 2 31  ? 175.113 224.736 213.026 1.00 45.63  ? 43  MET   A C     1 
ATOM   462  O O     . MET   C 2 31  ? 174.508 223.759 213.477 1.00 45.37  ? 43  MET   A O     1 
ATOM   463  C CB    . MET   C 2 31  ? 177.594 224.436 212.950 1.00 45.31  ? 43  MET   A CB    1 
ATOM   464  C CG    . MET   C 2 31  ? 178.712 223.700 212.246 1.00 48.64  ? 43  MET   A CG    1 
ATOM   465  S SD    . MET   C 2 31  ? 178.731 221.953 212.659 1.00 59.71  ? 43  MET   A SD    1 
ATOM   466  C CE    . MET   C 2 31  ? 178.996 222.066 214.419 1.00 53.57  ? 43  MET   A CE    1 
ATOM   467  N N     . CYS   C 2 32  ? 174.754 225.992 213.295 1.00 46.69  ? 44  CYS   A N     1 
ATOM   468  C CA    . CYS   C 2 32  ? 173.517 226.269 214.015 1.00 44.48  ? 44  CYS   A CA    1 
ATOM   469  C C     . CYS   C 2 32  ? 172.307 225.822 213.210 1.00 44.59  ? 44  CYS   A C     1 
ATOM   470  O O     . CYS   C 2 32  ? 171.343 225.291 213.771 1.00 44.80  ? 44  CYS   A O     1 
ATOM   471  C CB    . CYS   C 2 32  ? 173.422 227.758 214.341 1.00 45.22  ? 44  CYS   A CB    1 
ATOM   472  S SG    . CYS   C 2 32  ? 174.183 228.225 215.905 1.00 60.29  ? 44  CYS   A SG    1 
ATOM   473  N N     . THR   C 2 33  ? 172.334 226.035 211.892 1.00 46.40  ? 45  THR   A N     1 
ATOM   474  C CA    . THR   C 2 33  ? 171.240 225.545 211.060 1.00 44.49  ? 45  THR   A CA    1 
ATOM   475  C C     . THR   C 2 33  ? 171.202 224.023 211.008 1.00 44.18  ? 45  THR   A C     1 
ATOM   476  O O     . THR   C 2 33  ? 170.115 223.439 210.949 1.00 46.40  ? 45  THR   A O     1 
ATOM   477  C CB    . THR   C 2 33  ? 171.345 226.107 209.641 1.00 46.98  ? 45  THR   A CB    1 
ATOM   478  O OG1   . THR   C 2 33  ? 172.590 225.710 209.055 1.00 54.40  ? 45  THR   A OG1   1 
ATOM   479  C CG2   . THR   C 2 33  ? 171.243 227.623 209.653 1.00 45.22  ? 45  THR   A CG2   1 
ATOM   480  N N     . GLU   C 2 34  ? 172.360 223.366 211.031 1.00 43.42  ? 46  GLU   A N     1 
ATOM   481  C CA    . GLU   C 2 34  ? 172.407 221.911 210.989 1.00 43.34  ? 46  GLU   A CA    1 
ATOM   482  C C     . GLU   C 2 34  ? 172.122 221.265 212.338 1.00 44.83  ? 46  GLU   A C     1 
ATOM   483  O O     . GLU   C 2 34  ? 171.831 220.065 212.381 1.00 46.07  ? 46  GLU   A O     1 
ATOM   484  C CB    . GLU   C 2 34  ? 173.768 221.441 210.475 1.00 43.87  ? 46  GLU   A CB    1 
ATOM   485  C CG    . GLU   C 2 34  ? 174.065 221.869 209.053 1.00 49.62  ? 46  GLU   A CG    1 
ATOM   486  C CD    . GLU   C 2 34  ? 174.782 220.800 208.263 1.00 54.08  ? 46  GLU   A CD    1 
ATOM   487  O OE1   . GLU   C 2 34  ? 174.789 219.635 208.711 1.00 51.59  ? 46  GLU   A OE1   1 
ATOM   488  O OE2   . GLU   C 2 34  ? 175.337 221.124 207.195 1.00 58.22  ? 46  GLU   A OE2   1 
ATOM   489  N N     . LEU   C 2 35  ? 172.192 222.018 213.431 1.00 45.56  ? 47  LEU   A N     1 
ATOM   490  C CA    . LEU   C 2 35  ? 171.869 221.500 214.751 1.00 43.36  ? 47  LEU   A CA    1 
ATOM   491  C C     . LEU   C 2 35  ? 170.491 221.930 215.226 1.00 46.12  ? 47  LEU   A C     1 
ATOM   492  O O     . LEU   C 2 35  ? 170.056 221.494 216.296 1.00 52.22  ? 47  LEU   A O     1 
ATOM   493  C CB    . LEU   C 2 35  ? 172.930 221.937 215.767 1.00 47.26  ? 47  LEU   A CB    1 
ATOM   494  C CG    . LEU   C 2 35  ? 174.226 221.128 215.756 1.00 48.72  ? 47  LEU   A CG    1 
ATOM   495  C CD1   . LEU   C 2 35  ? 175.275 221.782 216.633 1.00 47.90  ? 47  LEU   A CD1   1 
ATOM   496  C CD2   . LEU   C 2 35  ? 173.962 219.705 216.208 1.00 50.85  ? 47  LEU   A CD2   1 
ATOM   497  N N     . LYS   C 2 36  ? 169.796 222.769 214.456 1.00 45.44  ? 48  LYS   A N     1 
ATOM   498  C CA    . LYS   C 2 36  ? 168.438 223.214 214.764 1.00 47.06  ? 48  LYS   A CA    1 
ATOM   499  C C     . LYS   C 2 36  ? 168.379 223.913 216.123 1.00 48.99  ? 48  LYS   A C     1 
ATOM   500  O O     . LYS   C 2 36  ? 167.606 223.550 217.012 1.00 49.26  ? 48  LYS   A O     1 
ATOM   501  C CB    . LYS   C 2 36  ? 167.452 222.043 214.698 1.00 49.18  ? 48  LYS   A CB    1 
ATOM   502  C CG    . LYS   C 2 36  ? 167.456 221.305 213.374 1.00 46.23  ? 48  LYS   A CG    1 
ATOM   503  C CD    . LYS   C 2 36  ? 166.884 222.168 212.266 1.00 49.12  ? 48  LYS   A CD    1 
ATOM   504  C CE    . LYS   C 2 36  ? 166.362 221.314 211.128 1.00 54.05  ? 48  LYS   A CE    1 
ATOM   505  N NZ    . LYS   C 2 36  ? 165.811 220.026 211.623 1.00 58.16  ? 48  LYS   A NZ    1 
ATOM   506  N N     . LEU   C 2 37  ? 169.214 224.936 216.267 1.00 47.20  ? 49  LEU   A N     1 
ATOM   507  C CA    . LEU   C 2 37  ? 169.248 225.761 217.466 1.00 47.48  ? 49  LEU   A CA    1 
ATOM   508  C C     . LEU   C 2 37  ? 168.594 227.106 217.183 1.00 46.44  ? 49  LEU   A C     1 
ATOM   509  O O     . LEU   C 2 37  ? 168.828 227.713 216.135 1.00 48.70  ? 49  LEU   A O     1 
ATOM   510  C CB    . LEU   C 2 37  ? 170.683 225.977 217.955 1.00 43.63  ? 49  LEU   A CB    1 
ATOM   511  C CG    . LEU   C 2 37  ? 171.550 224.742 218.187 1.00 45.32  ? 49  LEU   A CG    1 
ATOM   512  C CD1   . LEU   C 2 37  ? 173.021 225.096 218.090 1.00 42.68  ? 49  LEU   A CD1   1 
ATOM   513  C CD2   . LEU   C 2 37  ? 171.237 224.131 219.538 1.00 46.83  ? 49  LEU   A CD2   1 
ATOM   514  N N     . SER   C 2 38  ? 167.769 227.564 218.120 1.00 45.08  ? 50  SER   A N     1 
ATOM   515  C CA    . SER   C 2 38  ? 167.145 228.869 217.994 1.00 44.63  ? 50  SER   A CA    1 
ATOM   516  C C     . SER   C 2 38  ? 168.182 229.962 218.232 1.00 46.66  ? 50  SER   A C     1 
ATOM   517  O O     . SER   C 2 38  ? 169.360 229.697 218.484 1.00 48.54  ? 50  SER   A O     1 
ATOM   518  C CB    . SER   C 2 38  ? 165.975 228.998 218.965 1.00 47.46  ? 50  SER   A CB    1 
ATOM   519  O OG    . SER   C 2 38  ? 166.432 229.319 220.267 1.00 47.60  ? 50  SER   A OG    1 
ATOM   520  N N     . ASP   C 2 39  ? 167.739 231.217 218.141 1.00 48.89  ? 51  ASP   A N     1 
ATOM   521  C CA    . ASP   C 2 39  ? 168.656 232.329 218.353 1.00 49.71  ? 51  ASP   A CA    1 
ATOM   522  C C     . ASP   C 2 39  ? 169.196 232.338 219.776 1.00 49.08  ? 51  ASP   A C     1 
ATOM   523  O O     . ASP   C 2 39  ? 170.391 232.569 219.990 1.00 51.59  ? 51  ASP   A O     1 
ATOM   524  C CB    . ASP   C 2 39  ? 167.964 233.651 218.029 1.00 52.13  ? 51  ASP   A CB    1 
ATOM   525  C CG    . ASP   C 2 39  ? 168.540 234.320 216.800 1.00 58.92  ? 51  ASP   A CG    1 
ATOM   526  O OD1   . ASP   C 2 39  ? 169.296 233.655 216.064 1.00 56.05  ? 51  ASP   A OD1   1 
ATOM   527  O OD2   . ASP   C 2 39  ? 168.242 235.510 216.572 1.00 68.05  ? 51  ASP   A OD2   1 
ATOM   528  N N     . TYR   C 2 40  ? 168.336 232.082 220.763 1.00 46.13  ? 52  TYR   A N     1 
ATOM   529  C CA    . TYR   C 2 40  ? 168.791 232.095 222.149 1.00 42.90  ? 52  TYR   A CA    1 
ATOM   530  C C     . TYR   C 2 40  ? 169.817 230.997 222.400 1.00 46.05  ? 52  TYR   A C     1 
ATOM   531  O O     . TYR   C 2 40  ? 170.854 231.236 223.029 1.00 48.18  ? 52  TYR   A O     1 
ATOM   532  C CB    . TYR   C 2 40  ? 167.608 231.939 223.100 1.00 41.78  ? 52  TYR   A CB    1 
ATOM   533  C CG    . TYR   C 2 40  ? 167.925 232.400 224.500 1.00 43.16  ? 52  TYR   A CG    1 
ATOM   534  C CD1   . TYR   C 2 40  ? 168.195 233.732 224.762 1.00 50.81  ? 52  TYR   A CD1   1 
ATOM   535  C CD2   . TYR   C 2 40  ? 168.004 231.498 225.549 1.00 43.57  ? 52  TYR   A CD2   1 
ATOM   536  C CE1   . TYR   C 2 40  ? 168.497 234.161 226.038 1.00 53.09  ? 52  TYR   A CE1   1 
ATOM   537  C CE2   . TYR   C 2 40  ? 168.312 231.917 226.827 1.00 45.15  ? 52  TYR   A CE2   1 
ATOM   538  C CZ    . TYR   C 2 40  ? 168.559 233.249 227.065 1.00 46.38  ? 52  TYR   A CZ    1 
ATOM   539  O OH    . TYR   C 2 40  ? 168.865 233.676 228.334 1.00 44.49  ? 52  TYR   A OH    1 
ATOM   540  N N     . GLU   C 2 41  ? 169.540 229.783 221.921 1.00 44.62  ? 53  GLU   A N     1 
ATOM   541  C CA    . GLU   C 2 41  ? 170.491 228.690 222.095 1.00 44.01  ? 53  GLU   A CA    1 
ATOM   542  C C     . GLU   C 2 41  ? 171.755 228.920 221.277 1.00 48.09  ? 53  GLU   A C     1 
ATOM   543  O O     . GLU   C 2 41  ? 172.851 228.539 221.700 1.00 51.26  ? 53  GLU   A O     1 
ATOM   544  C CB    . GLU   C 2 41  ? 169.839 227.361 221.715 1.00 45.51  ? 53  GLU   A CB    1 
ATOM   545  C CG    . GLU   C 2 41  ? 168.773 226.897 222.687 1.00 47.70  ? 53  GLU   A CG    1 
ATOM   546  C CD    . GLU   C 2 41  ? 167.504 226.460 221.991 1.00 51.43  ? 53  GLU   A CD    1 
ATOM   547  O OE1   . GLU   C 2 41  ? 167.321 226.821 220.812 1.00 52.66  ? 53  GLU   A OE1   1 
ATOM   548  O OE2   . GLU   C 2 41  ? 166.689 225.754 222.618 1.00 51.95  ? 53  GLU   A OE2   1 
ATOM   549  N N     . GLY   C 2 42  ? 171.622 229.539 220.105 1.00 47.33  ? 54  GLY   A N     1 
ATOM   550  C CA    . GLY   C 2 42  ? 172.790 229.812 219.288 1.00 44.06  ? 54  GLY   A CA    1 
ATOM   551  C C     . GLY   C 2 42  ? 173.730 230.820 219.916 1.00 45.98  ? 54  GLY   A C     1 
ATOM   552  O O     . GLY   C 2 42  ? 174.925 230.832 219.613 1.00 51.87  ? 54  GLY   A O     1 
ATOM   553  N N     . ARG   C 2 43  ? 173.211 231.677 220.791 1.00 45.23  ? 55  ARG   A N     1 
ATOM   554  C CA    . ARG   C 2 43  ? 174.025 232.660 221.488 1.00 44.52  ? 55  ARG   A CA    1 
ATOM   555  C C     . ARG   C 2 43  ? 174.559 232.148 222.818 1.00 47.11  ? 55  ARG   A C     1 
ATOM   556  O O     . ARG   C 2 43  ? 175.275 232.881 223.504 1.00 51.62  ? 55  ARG   A O     1 
ATOM   557  C CB    . ARG   C 2 43  ? 173.224 233.946 221.714 1.00 41.99  ? 55  ARG   A CB    1 
ATOM   558  C CG    . ARG   C 2 43  ? 172.728 234.594 220.434 1.00 42.59  ? 55  ARG   A CG    1 
ATOM   559  C CD    . ARG   C 2 43  ? 171.774 235.738 220.723 1.00 41.78  ? 55  ARG   A CD    1 
ATOM   560  N NE    . ARG   C 2 43  ? 171.310 236.384 219.502 1.00 42.53  ? 55  ARG   A NE    1 
ATOM   561  C CZ    . ARG   C 2 43  ? 172.009 237.275 218.813 1.00 48.66  ? 55  ARG   A CZ    1 
ATOM   562  N NH1   . ARG   C 2 43  ? 173.214 237.659 219.201 1.00 50.93  ? 55  ARG   A NH1   1 
ATOM   563  N NH2   . ARG   C 2 43  ? 171.487 237.792 217.706 1.00 53.42  ? 55  ARG   A NH2   1 
ATOM   564  N N     . LEU   C 2 44  ? 174.225 230.918 223.198 1.00 46.02  ? 56  LEU   A N     1 
ATOM   565  C CA    . LEU   C 2 44  ? 174.756 230.345 224.425 1.00 46.13  ? 56  LEU   A CA    1 
ATOM   566  C C     . LEU   C 2 44  ? 176.250 230.084 224.284 1.00 45.64  ? 56  LEU   A C     1 
ATOM   567  O O     . LEU   C 2 44  ? 176.710 229.552 223.271 1.00 45.24  ? 56  LEU   A O     1 
ATOM   568  C CB    . LEU   C 2 44  ? 174.025 229.049 224.767 1.00 44.88  ? 56  LEU   A CB    1 
ATOM   569  C CG    . LEU   C 2 44  ? 173.898 228.716 226.252 1.00 43.98  ? 56  LEU   A CG    1 
ATOM   570  C CD1   . LEU   C 2 44  ? 173.096 229.785 226.963 1.00 46.14  ? 56  LEU   A CD1   1 
ATOM   571  C CD2   . LEU   C 2 44  ? 173.254 227.357 226.436 1.00 47.97  ? 56  LEU   A CD2   1 
ATOM   572  N N     . ILE   C 2 45  ? 177.009 230.463 225.313 1.00 45.50  ? 57  ILE   A N     1 
ATOM   573  C CA    . ILE   C 2 45  ? 178.456 230.299 225.259 1.00 44.91  ? 57  ILE   A CA    1 
ATOM   574  C C     . ILE   C 2 45  ? 178.842 228.827 225.345 1.00 43.99  ? 57  ILE   A C     1 
ATOM   575  O O     . ILE   C 2 45  ? 179.848 228.410 224.758 1.00 43.61  ? 57  ILE   A O     1 
ATOM   576  C CB    . ILE   C 2 45  ? 179.130 231.144 226.359 1.00 44.65  ? 57  ILE   A CB    1 
ATOM   577  C CG1   . ILE   C 2 45  ? 180.609 231.365 226.038 1.00 43.47  ? 57  ILE   A CG1   1 
ATOM   578  C CG2   . ILE   C 2 45  ? 178.958 230.511 227.726 1.00 48.70  ? 57  ILE   A CG2   1 
ATOM   579  C CD1   . ILE   C 2 45  ? 180.888 232.667 225.336 1.00 46.21  ? 57  ILE   A CD1   1 
ATOM   580  N N     . GLN   C 2 46  ? 178.058 228.014 226.058 1.00 42.34  ? 58  GLN   A N     1 
ATOM   581  C CA    . GLN   C 2 46  ? 178.370 226.592 226.163 1.00 43.30  ? 58  GLN   A CA    1 
ATOM   582  C C     . GLN   C 2 46  ? 178.162 225.880 224.832 1.00 44.47  ? 58  GLN   A C     1 
ATOM   583  O O     . GLN   C 2 46  ? 178.956 225.009 224.454 1.00 45.05  ? 58  GLN   A O     1 
ATOM   584  C CB    . GLN   C 2 46  ? 177.521 225.950 227.257 1.00 46.05  ? 58  GLN   A CB    1 
ATOM   585  C CG    . GLN   C 2 46  ? 178.021 226.223 228.663 1.00 46.07  ? 58  GLN   A CG    1 
ATOM   586  C CD    . GLN   C 2 46  ? 177.545 227.552 229.201 1.00 46.95  ? 58  GLN   A CD    1 
ATOM   587  O OE1   . GLN   C 2 46  ? 176.726 228.229 228.581 1.00 48.06  ? 58  GLN   A OE1   1 
ATOM   588  N NE2   . GLN   C 2 46  ? 178.053 227.935 230.363 1.00 45.80  ? 58  GLN   A NE2   1 
ATOM   589  N N     . ASN   C 2 47  ? 177.101 226.241 224.107 1.00 42.43  ? 59  ASN   A N     1 
ATOM   590  C CA    . ASN   C 2 47  ? 176.885 225.674 222.780 1.00 41.54  ? 59  ASN   A CA    1 
ATOM   591  C C     . ASN   C 2 47  ? 178.016 226.051 221.834 1.00 41.83  ? 59  ASN   A C     1 
ATOM   592  O O     . ASN   C 2 47  ? 178.486 225.218 221.049 1.00 44.68  ? 59  ASN   A O     1 
ATOM   593  C CB    . ASN   C 2 47  ? 175.540 226.139 222.227 1.00 42.21  ? 59  ASN   A CB    1 
ATOM   594  C CG    . ASN   C 2 47  ? 174.368 225.466 222.910 1.00 43.43  ? 59  ASN   A CG    1 
ATOM   595  O OD1   . ASN   C 2 47  ? 174.509 224.394 223.494 1.00 49.34  ? 59  ASN   A OD1   1 
ATOM   596  N ND2   . ASN   C 2 47  ? 173.201 226.093 222.838 1.00 41.33  ? 59  ASN   A ND2   1 
ATOM   597  N N     . SER   C 2 48  ? 178.468 227.306 221.892 1.00 41.70  ? 60  SER   A N     1 
ATOM   598  C CA    . SER   C 2 48  ? 179.589 227.722 221.058 1.00 42.99  ? 60  SER   A CA    1 
ATOM   599  C C     . SER   C 2 48  ? 180.857 226.966 221.426 1.00 42.15  ? 60  SER   A C     1 
ATOM   600  O O     . SER   C 2 48  ? 181.617 226.550 220.546 1.00 44.11  ? 60  SER   A O     1 
ATOM   601  C CB    . SER   C 2 48  ? 179.810 229.229 221.175 1.00 46.14  ? 60  SER   A CB    1 
ATOM   602  O OG    . SER   C 2 48  ? 180.194 229.588 222.489 1.00 51.36  ? 60  SER   A OG    1 
ATOM   603  N N     . LEU   C 2 49  ? 181.103 226.778 222.725 1.00 40.67  ? 61  LEU   A N     1 
ATOM   604  C CA    . LEU   C 2 49  ? 182.269 226.015 223.160 1.00 40.94  ? 61  LEU   A CA    1 
ATOM   605  C C     . LEU   C 2 49  ? 182.220 224.589 222.630 1.00 40.21  ? 61  LEU   A C     1 
ATOM   606  O O     . LEU   C 2 49  ? 183.229 224.063 222.146 1.00 38.60  ? 61  LEU   A O     1 
ATOM   607  C CB    . LEU   C 2 49  ? 182.353 226.019 224.687 1.00 41.03  ? 61  LEU   A CB    1 
ATOM   608  C CG    . LEU   C 2 49  ? 183.341 226.962 225.379 1.00 40.96  ? 61  LEU   A CG    1 
ATOM   609  C CD1   . LEU   C 2 49  ? 184.762 226.602 225.012 1.00 42.59  ? 61  LEU   A CD1   1 
ATOM   610  C CD2   . LEU   C 2 49  ? 183.056 228.408 225.025 1.00 45.57  ? 61  LEU   A CD2   1 
ATOM   611  N N     . THR   C 2 50  ? 181.050 223.952 222.706 1.00 42.28  ? 62  THR   A N     1 
ATOM   612  C CA    . THR   C 2 50  ? 180.906 222.594 222.195 1.00 41.93  ? 62  THR   A CA    1 
ATOM   613  C C     . THR   C 2 50  ? 181.151 222.538 220.692 1.00 41.42  ? 62  THR   A C     1 
ATOM   614  O O     . THR   C 2 50  ? 181.860 221.649 220.202 1.00 44.81  ? 62  THR   A O     1 
ATOM   615  C CB    . THR   C 2 50  ? 179.517 222.051 222.533 1.00 43.22  ? 62  THR   A CB    1 
ATOM   616  O OG1   . THR   C 2 50  ? 179.451 221.743 223.930 1.00 48.12  ? 62  THR   A OG1   1 
ATOM   617  C CG2   . THR   C 2 50  ? 179.219 220.799 221.730 1.00 44.31  ? 62  THR   A CG2   1 
ATOM   618  N N     . ILE   C 2 51  ? 180.578 223.484 219.945 1.00 42.21  ? 63  ILE   A N     1 
ATOM   619  C CA    . ILE   C 2 51  ? 180.773 223.508 218.497 1.00 43.43  ? 63  ILE   A CA    1 
ATOM   620  C C     . ILE   C 2 51  ? 182.251 223.669 218.166 1.00 42.95  ? 63  ILE   A C     1 
ATOM   621  O O     . ILE   C 2 51  ? 182.806 222.928 217.345 1.00 44.11  ? 63  ILE   A O     1 
ATOM   622  C CB    . ILE   C 2 51  ? 179.923 224.624 217.861 1.00 42.09  ? 63  ILE   A CB    1 
ATOM   623  C CG1   . ILE   C 2 51  ? 178.434 224.290 217.971 1.00 41.15  ? 63  ILE   A CG1   1 
ATOM   624  C CG2   . ILE   C 2 51  ? 180.322 224.845 216.413 1.00 42.50  ? 63  ILE   A CG2   1 
ATOM   625  C CD1   . ILE   C 2 51  ? 177.549 225.139 217.094 1.00 45.36  ? 63  ILE   A CD1   1 
ATOM   626  N N     . GLU   C 2 52  ? 182.915 224.617 218.831 1.00 40.70  ? 64  GLU   A N     1 
ATOM   627  C CA    . GLU   C 2 52  ? 184.332 224.860 218.578 1.00 40.54  ? 64  GLU   A CA    1 
ATOM   628  C C     . GLU   C 2 52  ? 185.159 223.621 218.884 1.00 42.44  ? 64  GLU   A C     1 
ATOM   629  O O     . GLU   C 2 52  ? 186.078 223.269 218.132 1.00 42.62  ? 64  GLU   A O     1 
ATOM   630  C CB    . GLU   C 2 52  ? 184.815 226.041 219.421 1.00 42.48  ? 64  GLU   A CB    1 
ATOM   631  C CG    . GLU   C 2 52  ? 184.175 227.369 219.091 1.00 40.79  ? 64  GLU   A CG    1 
ATOM   632  C CD    . GLU   C 2 52  ? 184.185 228.331 220.259 1.00 43.10  ? 64  GLU   A CD    1 
ATOM   633  O OE1   . GLU   C 2 52  ? 184.400 227.877 221.401 1.00 44.99  ? 64  GLU   A OE1   1 
ATOM   634  O OE2   . GLU   C 2 52  ? 183.972 229.539 220.041 1.00 45.59  ? 64  GLU   A OE2   1 
ATOM   635  N N     . ARG   C 2 53  ? 184.852 222.948 219.995 1.00 42.84  ? 65  ARG   A N     1 
ATOM   636  C CA    . ARG   C 2 53  ? 185.595 221.747 220.353 1.00 40.31  ? 65  ARG   A CA    1 
ATOM   637  C C     . ARG   C 2 53  ? 185.394 220.651 219.319 1.00 41.02  ? 65  ARG   A C     1 
ATOM   638  O O     . ARG   C 2 53  ? 186.335 219.919 218.995 1.00 43.65  ? 65  ARG   A O     1 
ATOM   639  C CB    . ARG   C 2 53  ? 185.185 221.270 221.746 1.00 40.17  ? 65  ARG   A CB    1 
ATOM   640  C CG    . ARG   C 2 53  ? 185.819 222.075 222.868 1.00 41.36  ? 65  ARG   A CG    1 
ATOM   641  C CD    . ARG   C 2 53  ? 184.951 222.081 224.117 1.00 47.25  ? 65  ARG   A CD    1 
ATOM   642  N NE    . ARG   C 2 53  ? 184.961 220.810 224.835 1.00 49.02  ? 65  ARG   A NE    1 
ATOM   643  C CZ    . ARG   C 2 53  ? 186.042 220.209 225.314 1.00 52.37  ? 65  ARG   A CZ    1 
ATOM   644  N NH1   . ARG   C 2 53  ? 187.239 220.767 225.239 1.00 48.92  ? 65  ARG   A NH1   1 
ATOM   645  N NH2   . ARG   C 2 53  ? 185.916 219.025 225.903 1.00 62.52  ? 65  ARG   A NH2   1 
ATOM   646  N N     . MET   C 2 54  ? 184.179 220.524 218.784 1.00 41.47  ? 66  MET   A N     1 
ATOM   647  C CA    . MET   C 2 54  ? 183.945 219.533 217.736 1.00 41.81  ? 66  MET   A CA    1 
ATOM   648  C C     . MET   C 2 54  ? 184.766 219.846 216.490 1.00 42.39  ? 66  MET   A C     1 
ATOM   649  O O     . MET   C 2 54  ? 185.346 218.944 215.871 1.00 43.99  ? 66  MET   A O     1 
ATOM   650  C CB    . MET   C 2 54  ? 182.455 219.448 217.404 1.00 42.06  ? 66  MET   A CB    1 
ATOM   651  C CG    . MET   C 2 54  ? 181.593 219.030 218.584 1.00 48.62  ? 66  MET   A CG    1 
ATOM   652  S SD    . MET   C 2 54  ? 179.826 218.934 218.233 1.00 57.03  ? 66  MET   A SD    1 
ATOM   653  C CE    . MET   C 2 54  ? 179.795 219.349 216.500 1.00 43.31  ? 66  MET   A CE    1 
ATOM   654  N N     . VAL   C 2 55  ? 184.838 221.126 216.111 1.00 43.83  ? 67  VAL   A N     1 
ATOM   655  C CA    . VAL   C 2 55  ? 185.647 221.498 214.946 1.00 41.36  ? 67  VAL   A CA    1 
ATOM   656  C C     . VAL   C 2 55  ? 187.111 221.162 215.182 1.00 40.53  ? 67  VAL   A C     1 
ATOM   657  O O     . VAL   C 2 55  ? 187.786 220.599 214.313 1.00 40.36  ? 67  VAL   A O     1 
ATOM   658  C CB    . VAL   C 2 55  ? 185.481 222.988 214.608 1.00 42.01  ? 67  VAL   A CB    1 
ATOM   659  C CG1   . VAL   C 2 55  ? 185.936 223.248 213.184 1.00 42.01  ? 67  VAL   A CG1   1 
ATOM   660  C CG2   . VAL   C 2 55  ? 184.070 223.398 214.775 1.00 46.55  ? 67  VAL   A CG2   1 
ATOM   661  N N     . LEU   C 2 56  ? 187.628 221.519 216.358 1.00 41.73  ? 68  LEU   A N     1 
ATOM   662  C CA    . LEU   C 2 56  ? 189.038 221.274 216.639 1.00 43.09  ? 68  LEU   A CA    1 
ATOM   663  C C     . LEU   C 2 56  ? 189.341 219.784 216.686 1.00 43.41  ? 68  LEU   A C     1 
ATOM   664  O O     . LEU   C 2 56  ? 190.401 219.343 216.227 1.00 46.33  ? 68  LEU   A O     1 
ATOM   665  C CB    . LEU   C 2 56  ? 189.441 221.952 217.946 1.00 42.71  ? 68  LEU   A CB    1 
ATOM   666  C CG    . LEU   C 2 56  ? 189.250 223.466 217.937 1.00 40.15  ? 68  LEU   A CG    1 
ATOM   667  C CD1   . LEU   C 2 56  ? 189.551 224.058 219.300 1.00 40.93  ? 68  LEU   A CD1   1 
ATOM   668  C CD2   . LEU   C 2 56  ? 190.103 224.101 216.857 1.00 40.34  ? 68  LEU   A CD2   1 
ATOM   669  N N     . SER   C 2 57  ? 188.420 218.990 217.235 1.00 43.04  ? 69  SER   A N     1 
ATOM   670  C CA    . SER   C 2 57  ? 188.623 217.548 217.286 1.00 43.74  ? 69  SER   A CA    1 
ATOM   671  C C     . SER   C 2 57  ? 188.564 216.922 215.902 1.00 45.46  ? 69  SER   A C     1 
ATOM   672  O O     . SER   C 2 57  ? 189.269 215.942 215.638 1.00 48.55  ? 69  SER   A O     1 
ATOM   673  C CB    . SER   C 2 57  ? 187.581 216.910 218.201 1.00 42.07  ? 69  SER   A CB    1 
ATOM   674  O OG    . SER   C 2 57  ? 187.755 215.506 218.259 1.00 48.85  ? 69  SER   A OG    1 
ATOM   675  N N     . ALA   C 2 58  ? 187.735 217.467 215.008 1.00 44.94  ? 70  ALA   A N     1 
ATOM   676  C CA    . ALA   C 2 58  ? 187.611 216.888 213.674 1.00 43.47  ? 70  ALA   A CA    1 
ATOM   677  C C     . ALA   C 2 58  ? 188.916 216.992 212.891 1.00 44.74  ? 70  ALA   A C     1 
ATOM   678  O O     . ALA   C 2 58  ? 189.252 216.090 212.115 1.00 46.49  ? 70  ALA   A O     1 
ATOM   679  C CB    . ALA   C 2 58  ? 186.475 217.567 212.912 1.00 43.42  ? 70  ALA   A CB    1 
ATOM   680  N N     . PHE   C 2 59  ? 189.662 218.079 213.075 1.00 45.50  ? 71  PHE   A N     1 
ATOM   681  C CA    . PHE   C 2 59  ? 190.874 218.326 212.306 1.00 46.00  ? 71  PHE   A CA    1 
ATOM   682  C C     . PHE   C 2 59  ? 192.145 217.865 213.007 1.00 50.35  ? 71  PHE   A C     1 
ATOM   683  O O     . PHE   C 2 59  ? 193.239 218.103 212.488 1.00 56.21  ? 71  PHE   A O     1 
ATOM   684  C CB    . PHE   C 2 59  ? 190.991 219.815 211.969 1.00 45.19  ? 71  PHE   A CB    1 
ATOM   685  C CG    . PHE   C 2 59  ? 190.224 220.223 210.746 1.00 42.46  ? 71  PHE   A CG    1 
ATOM   686  C CD1   . PHE   C 2 59  ? 188.869 220.485 210.817 1.00 41.53  ? 71  PHE   A CD1   1 
ATOM   687  C CD2   . PHE   C 2 59  ? 190.860 220.338 209.523 1.00 41.63  ? 71  PHE   A CD2   1 
ATOM   688  C CE1   . PHE   C 2 59  ? 188.164 220.862 209.694 1.00 40.68  ? 71  PHE   A CE1   1 
ATOM   689  C CE2   . PHE   C 2 59  ? 190.159 220.712 208.397 1.00 41.60  ? 71  PHE   A CE2   1 
ATOM   690  C CZ    . PHE   C 2 59  ? 188.810 220.971 208.482 1.00 41.57  ? 71  PHE   A CZ    1 
ATOM   691  N N     . ASP   C 2 60  ? 192.037 217.215 214.164 1.00 51.76  ? 72  ASP   A N     1 
ATOM   692  C CA    . ASP   C 2 60  ? 193.211 216.750 214.902 1.00 52.51  ? 72  ASP   A CA    1 
ATOM   693  C C     . ASP   C 2 60  ? 193.748 215.498 214.220 1.00 54.84  ? 72  ASP   A C     1 
ATOM   694  O O     . ASP   C 2 60  ? 193.234 214.398 214.422 1.00 54.33  ? 72  ASP   A O     1 
ATOM   695  C CB    . ASP   C 2 60  ? 192.852 216.482 216.359 1.00 49.83  ? 72  ASP   A CB    1 
ATOM   696  C CG    . ASP   C 2 60  ? 194.070 216.350 217.246 1.00 52.79  ? 72  ASP   A CG    1 
ATOM   697  O OD1   . ASP   C 2 60  ? 195.193 216.243 216.714 1.00 54.19  ? 72  ASP   A OD1   1 
ATOM   698  O OD2   . ASP   C 2 60  ? 193.904 216.356 218.483 1.00 56.86  ? 72  ASP   A OD2   1 
ATOM   699  N N     . GLU   C 2 61  ? 194.800 215.662 213.416 1.00 57.57  ? 73  GLU   A N     1 
ATOM   700  C CA    . GLU   C 2 61  ? 195.304 214.564 212.595 1.00 55.21  ? 73  GLU   A CA    1 
ATOM   701  C C     . GLU   C 2 61  ? 195.907 213.451 213.447 1.00 51.76  ? 73  GLU   A C     1 
ATOM   702  O O     . GLU   C 2 61  ? 195.579 212.271 213.273 1.00 52.90  ? 73  GLU   A O     1 
ATOM   703  C CB    . GLU   C 2 61  ? 196.336 215.095 211.599 1.00 61.77  ? 73  GLU   A CB    1 
ATOM   704  C CG    . GLU   C 2 61  ? 196.563 214.209 210.381 1.00 77.17  ? 73  GLU   A CG    1 
ATOM   705  C CD    . GLU   C 2 61  ? 195.442 214.294 209.359 1.00 98.10  ? 73  GLU   A CD    1 
ATOM   706  O OE1   . GLU   C 2 61  ? 194.387 214.889 209.660 1.00 93.78  ? 73  GLU   A OE1   1 
ATOM   707  O OE2   . GLU   C 2 61  ? 195.623 213.761 208.243 1.00 116.06 ? 73  GLU   A OE2   1 
ATOM   708  N N     . ARG   C 2 62  ? 196.802 213.807 214.372 1.00 49.82  ? 74  ARG   A N     1 
ATOM   709  C CA    . ARG   C 2 62  ? 197.531 212.799 215.134 1.00 48.67  ? 74  ARG   A CA    1 
ATOM   710  C C     . ARG   C 2 62  ? 196.604 212.023 216.060 1.00 49.02  ? 74  ARG   A C     1 
ATOM   711  O O     . ARG   C 2 62  ? 196.671 210.790 216.140 1.00 48.47  ? 74  ARG   A O     1 
ATOM   712  C CB    . ARG   C 2 62  ? 198.655 213.456 215.934 1.00 49.95  ? 74  ARG   A CB    1 
ATOM   713  C CG    . ARG   C 2 62  ? 199.679 212.468 216.454 1.00 56.66  ? 74  ARG   A CG    1 
ATOM   714  C CD    . ARG   C 2 62  ? 200.828 213.173 217.145 1.00 63.34  ? 74  ARG   A CD    1 
ATOM   715  N NE    . ARG   C 2 62  ? 200.441 213.687 218.453 1.00 74.83  ? 74  ARG   A NE    1 
ATOM   716  C CZ    . ARG   C 2 62  ? 200.255 212.934 219.529 1.00 72.55  ? 74  ARG   A CZ    1 
ATOM   717  N NH1   . ARG   C 2 62  ? 200.417 211.622 219.493 1.00 68.76  ? 74  ARG   A NH1   1 
ATOM   718  N NH2   . ARG   C 2 62  ? 199.901 213.514 220.672 1.00 69.78  ? 74  ARG   A NH2   1 
ATOM   719  N N     . ARG   C 2 63  ? 195.746 212.736 216.790 1.00 48.71  ? 75  ARG   A N     1 
ATOM   720  C CA    . ARG   C 2 63  ? 194.832 212.063 217.704 1.00 47.01  ? 75  ARG   A CA    1 
ATOM   721  C C     . ARG   C 2 63  ? 193.851 211.185 216.944 1.00 47.61  ? 75  ARG   A C     1 
ATOM   722  O O     . ARG   C 2 63  ? 193.534 210.076 217.384 1.00 49.24  ? 75  ARG   A O     1 
ATOM   723  C CB    . ARG   C 2 63  ? 194.088 213.084 218.566 1.00 48.01  ? 75  ARG   A CB    1 
ATOM   724  C CG    . ARG   C 2 63  ? 192.826 212.533 219.208 1.00 43.56  ? 75  ARG   A CG    1 
ATOM   725  C CD    . ARG   C 2 63  ? 192.153 213.552 220.107 1.00 46.41  ? 75  ARG   A CD    1 
ATOM   726  N NE    . ARG   C 2 63  ? 191.023 212.977 220.827 1.00 42.62  ? 75  ARG   A NE    1 
ATOM   727  C CZ    . ARG   C 2 63  ? 191.131 212.131 221.842 1.00 48.24  ? 75  ARG   A CZ    1 
ATOM   728  N NH1   . ARG   C 2 63  ? 192.310 211.747 222.301 1.00 53.10  ? 75  ARG   A NH1   1 
ATOM   729  N NH2   . ARG   C 2 63  ? 190.028 211.661 222.414 1.00 50.23  ? 75  ARG   A NH2   1 
ATOM   730  N N     . ASN   C 2 64  ? 193.363 211.659 215.796 1.00 48.55  ? 76  ASN   A N     1 
ATOM   731  C CA    . ASN   C 2 64  ? 192.446 210.851 215.000 1.00 46.66  ? 76  ASN   A CA    1 
ATOM   732  C C     . ASN   C 2 64  ? 193.130 209.598 214.477 1.00 45.78  ? 76  ASN   A C     1 
ATOM   733  O O     . ASN   C 2 64  ? 192.540 208.514 214.486 1.00 46.61  ? 76  ASN   A O     1 
ATOM   734  C CB    . ASN   C 2 64  ? 191.878 211.670 213.846 1.00 45.79  ? 76  ASN   A CB    1 
ATOM   735  C CG    . ASN   C 2 64  ? 190.826 212.649 214.299 1.00 48.47  ? 76  ASN   A CG    1 
ATOM   736  O OD1   . ASN   C 2 64  ? 190.386 212.611 215.447 1.00 46.94  ? 76  ASN   A OD1   1 
ATOM   737  N ND2   . ASN   C 2 64  ? 190.413 213.535 213.403 1.00 51.61  ? 76  ASN   A ND2   1 
ATOM   738  N N     . LYS   C 2 65  ? 194.377 209.725 214.018 1.00 47.16  ? 77  LYS   A N     1 
ATOM   739  C CA    . LYS   C 2 65  ? 195.112 208.556 213.548 1.00 46.40  ? 77  LYS   A CA    1 
ATOM   740  C C     . LYS   C 2 65  ? 195.328 207.550 214.671 1.00 46.26  ? 77  LYS   A C     1 
ATOM   741  O O     . LYS   C 2 65  ? 195.126 206.343 214.482 1.00 49.83  ? 77  LYS   A O     1 
ATOM   742  C CB    . LYS   C 2 65  ? 196.449 208.989 212.951 1.00 46.70  ? 77  LYS   A CB    1 
ATOM   743  C CG    . LYS   C 2 65  ? 196.737 208.413 211.580 1.00 46.36  ? 77  LYS   A CG    1 
ATOM   744  C CD    . LYS   C 2 65  ? 198.072 208.905 211.055 1.00 46.59  ? 77  LYS   A CD    1 
ATOM   745  C CE    . LYS   C 2 65  ? 199.172 208.710 212.082 1.00 45.85  ? 77  LYS   A CE    1 
ATOM   746  N NZ    . LYS   C 2 65  ? 200.520 208.926 211.492 1.00 51.40  ? 77  LYS   A NZ    1 
ATOM   747  N N     . TYR   C 2 66  ? 195.733 208.028 215.852 1.00 41.80  ? 78  TYR   A N     1 
ATOM   748  C CA    . TYR   C 2 66  ? 195.944 207.124 216.978 1.00 42.09  ? 78  TYR   A CA    1 
ATOM   749  C C     . TYR   C 2 66  ? 194.641 206.453 217.397 1.00 45.46  ? 78  TYR   A C     1 
ATOM   750  O O     . TYR   C 2 66  ? 194.618 205.251 217.684 1.00 47.08  ? 78  TYR   A O     1 
ATOM   751  C CB    . TYR   C 2 66  ? 196.570 207.883 218.150 1.00 43.75  ? 78  TYR   A CB    1 
ATOM   752  C CG    . TYR   C 2 66  ? 196.927 207.021 219.345 1.00 44.51  ? 78  TYR   A CG    1 
ATOM   753  C CD1   . TYR   C 2 66  ? 195.954 206.579 220.232 1.00 42.20  ? 78  TYR   A CD1   1 
ATOM   754  C CD2   . TYR   C 2 66  ? 198.240 206.639 219.577 1.00 44.31  ? 78  TYR   A CD2   1 
ATOM   755  C CE1   . TYR   C 2 66  ? 196.278 205.791 221.313 1.00 43.36  ? 78  TYR   A CE1   1 
ATOM   756  C CE2   . TYR   C 2 66  ? 198.574 205.851 220.656 1.00 44.32  ? 78  TYR   A CE2   1 
ATOM   757  C CZ    . TYR   C 2 66  ? 197.589 205.430 221.520 1.00 49.36  ? 78  TYR   A CZ    1 
ATOM   758  O OH    . TYR   C 2 66  ? 197.920 204.644 222.598 1.00 64.28  ? 78  TYR   A OH    1 
ATOM   759  N N     . LEU   C 2 67  ? 193.546 207.214 217.443 1.00 45.29  ? 79  LEU   A N     1 
ATOM   760  C CA    . LEU   C 2 67  ? 192.255 206.647 217.809 1.00 44.09  ? 79  LEU   A CA    1 
ATOM   761  C C     . LEU   C 2 67  ? 191.801 205.616 216.787 1.00 46.17  ? 79  LEU   A C     1 
ATOM   762  O O     . LEU   C 2 67  ? 191.205 204.594 217.143 1.00 48.46  ? 79  LEU   A O     1 
ATOM   763  C CB    . LEU   C 2 67  ? 191.221 207.764 217.950 1.00 44.50  ? 79  LEU   A CB    1 
ATOM   764  C CG    . LEU   C 2 67  ? 190.212 207.644 219.089 1.00 48.11  ? 79  LEU   A CG    1 
ATOM   765  C CD1   . LEU   C 2 67  ? 190.929 207.507 220.417 1.00 49.82  ? 79  LEU   A CD1   1 
ATOM   766  C CD2   . LEU   C 2 67  ? 189.289 208.845 219.101 1.00 46.53  ? 79  LEU   A CD2   1 
ATOM   767  N N     . GLU   C 2 68  ? 192.064 205.876 215.506 1.00 46.51  ? 80  GLU   A N     1 
ATOM   768  C CA    . GLU   C 2 68  ? 191.740 204.913 214.463 1.00 45.77  ? 80  GLU   A CA    1 
ATOM   769  C C     . GLU   C 2 68  ? 192.538 203.629 214.636 1.00 48.20  ? 80  GLU   A C     1 
ATOM   770  O O     . GLU   C 2 68  ? 191.994 202.527 214.502 1.00 50.91  ? 80  GLU   A O     1 
ATOM   771  C CB    . GLU   C 2 68  ? 192.016 205.536 213.097 1.00 47.10  ? 80  GLU   A CB    1 
ATOM   772  C CG    . GLU   C 2 68  ? 191.100 205.078 211.988 1.00 53.17  ? 80  GLU   A CG    1 
ATOM   773  C CD    . GLU   C 2 68  ? 190.933 206.140 210.922 1.00 62.43  ? 80  GLU   A CD    1 
ATOM   774  O OE1   . GLU   C 2 68  ? 191.951 206.551 210.329 1.00 64.75  ? 80  GLU   A OE1   1 
ATOM   775  O OE2   . GLU   C 2 68  ? 189.786 206.567 210.683 1.00 65.41  ? 80  GLU   A OE2   1 
ATOM   776  N N     . GLU   C 2 69  ? 193.832 203.751 214.937 1.00 47.87  ? 81  GLU   A N     1 
ATOM   777  C CA    . GLU   C 2 69  ? 194.658 202.561 215.102 1.00 45.45  ? 81  GLU   A CA    1 
ATOM   778  C C     . GLU   C 2 69  ? 194.404 201.874 216.439 1.00 48.43  ? 81  GLU   A C     1 
ATOM   779  O O     . GLU   C 2 69  ? 194.555 200.652 216.542 1.00 53.79  ? 81  GLU   A O     1 
ATOM   780  C CB    . GLU   C 2 69  ? 196.133 202.926 214.957 1.00 45.89  ? 81  GLU   A CB    1 
ATOM   781  C CG    . GLU   C 2 69  ? 196.500 203.423 213.573 1.00 47.86  ? 81  GLU   A CG    1 
ATOM   782  C CD    . GLU   C 2 69  ? 197.988 203.608 213.398 1.00 57.96  ? 81  GLU   A CD    1 
ATOM   783  O OE1   . GLU   C 2 69  ? 198.728 203.434 214.388 1.00 63.07  ? 81  GLU   A OE1   1 
ATOM   784  O OE2   . GLU   C 2 69  ? 198.420 203.928 212.272 1.00 61.05  ? 81  GLU   A OE2   1 
ATOM   785  N N     . HIS   C 2 70  ? 194.021 202.632 217.465 1.00 47.00  ? 82  HIS   A N     1 
ATOM   786  C CA    . HIS   C 2 70  ? 193.699 202.090 218.787 1.00 44.49  ? 82  HIS   A CA    1 
ATOM   787  C C     . HIS   C 2 70  ? 192.324 202.596 219.201 1.00 47.11  ? 82  HIS   A C     1 
ATOM   788  O O     . HIS   C 2 70  ? 192.211 203.584 219.940 1.00 50.01  ? 82  HIS   A O     1 
ATOM   789  C CB    . HIS   C 2 70  ? 194.755 202.474 219.825 1.00 46.48  ? 82  HIS   A CB    1 
ATOM   790  C CG    . HIS   C 2 70  ? 196.155 202.109 219.439 1.00 46.97  ? 82  HIS   A CG    1 
ATOM   791  N ND1   . HIS   C 2 70  ? 196.792 202.645 218.342 1.00 46.48  ? 82  HIS   A ND1   1 
ATOM   792  C CD2   . HIS   C 2 70  ? 197.046 201.270 220.017 1.00 47.24  ? 82  HIS   A CD2   1 
ATOM   793  C CE1   . HIS   C 2 70  ? 198.012 202.146 218.256 1.00 48.38  ? 82  HIS   A CE1   1 
ATOM   794  N NE2   . HIS   C 2 70  ? 198.191 201.308 219.260 1.00 46.18  ? 82  HIS   A NE2   1 
ATOM   795  N N     . PRO   C 2 71  ? 191.255 201.947 218.737 1.00 47.90  ? 83  PRO   A N     1 
ATOM   796  C CA    . PRO   C 2 71  ? 189.902 202.415 219.071 1.00 50.09  ? 83  PRO   A CA    1 
ATOM   797  C C     . PRO   C 2 71  ? 189.656 202.419 220.572 1.00 51.41  ? 83  PRO   A C     1 
ATOM   798  O O     . PRO   C 2 71  ? 190.134 201.550 221.303 1.00 54.73  ? 83  PRO   A O     1 
ATOM   799  C CB    . PRO   C 2 71  ? 188.995 201.409 218.356 1.00 49.42  ? 83  PRO   A CB    1 
ATOM   800  C CG    . PRO   C 2 71  ? 189.839 200.848 217.264 1.00 50.95  ? 83  PRO   A CG    1 
ATOM   801  C CD    . PRO   C 2 71  ? 191.232 200.808 217.806 1.00 48.24  ? 83  PRO   A CD    1 
ATOM   802  N N     . SER   C 2 72  ? 188.897 203.413 221.025 1.00 48.76  ? 84  SER   A N     1 
ATOM   803  C CA    . SER   C 2 72  ? 188.637 203.599 222.445 1.00 51.78  ? 84  SER   A CA    1 
ATOM   804  C C     . SER   C 2 72  ? 187.523 202.654 222.891 1.00 57.55  ? 84  SER   A C     1 
ATOM   805  O O     . SER   C 2 72  ? 187.051 201.804 222.131 1.00 60.10  ? 84  SER   A O     1 
ATOM   806  C CB    . SER   C 2 72  ? 188.303 205.059 222.731 1.00 50.01  ? 84  SER   A CB    1 
ATOM   807  O OG    . SER   C 2 72  ? 188.194 205.292 224.123 1.00 54.11  ? 84  SER   A OG    1 
ATOM   808  N N     . ALA   C 2 73  ? 187.090 202.792 224.141 1.00 56.19  ? 85  ALA   A N     1 
ATOM   809  C CA    . ALA   C 2 73  ? 186.087 201.903 224.723 1.00 56.47  ? 85  ALA   A CA    1 
ATOM   810  C C     . ALA   C 2 73  ? 184.704 202.488 224.472 1.00 56.29  ? 85  ALA   A C     1 
ATOM   811  O O     . ALA   C 2 73  ? 184.273 203.415 225.162 1.00 59.71  ? 85  ALA   A O     1 
ATOM   812  C CB    . ALA   C 2 73  ? 186.345 201.704 226.212 1.00 63.36  ? 85  ALA   A CB    1 
ATOM   813  N N     . GLY   C 2 74  ? 184.002 201.943 223.481 1.00 53.38  ? 86  GLY   A N     1 
ATOM   814  C CA    . GLY   C 2 74  ? 182.651 202.362 223.184 1.00 53.89  ? 86  GLY   A CA    1 
ATOM   815  C C     . GLY   C 2 74  ? 182.530 203.663 222.429 1.00 53.95  ? 86  GLY   A C     1 
ATOM   816  O O     . GLY   C 2 74  ? 181.407 204.133 222.214 1.00 57.70  ? 86  GLY   A O     1 
ATOM   817  N N     . LYS   C 2 75  ? 183.643 204.263 222.018 1.00 51.76  ? 87  LYS   A N     1 
ATOM   818  C CA    . LYS   C 2 75  ? 183.644 205.521 221.279 1.00 52.27  ? 87  LYS   A CA    1 
ATOM   819  C C     . LYS   C 2 75  ? 184.359 205.274 219.957 1.00 55.61  ? 87  LYS   A C     1 
ATOM   820  O O     . LYS   C 2 75  ? 185.585 205.135 219.926 1.00 63.45  ? 87  LYS   A O     1 
ATOM   821  C CB    . LYS   C 2 75  ? 184.323 206.626 222.082 1.00 53.85  ? 87  LYS   A CB    1 
ATOM   822  C CG    . LYS   C 2 75  ? 183.587 207.003 223.350 1.00 53.13  ? 87  LYS   A CG    1 
ATOM   823  C CD    . LYS   C 2 75  ? 184.366 208.021 224.157 1.00 53.57  ? 87  LYS   A CD    1 
ATOM   824  C CE    . LYS   C 2 75  ? 183.752 208.204 225.530 1.00 58.71  ? 87  LYS   A CE    1 
ATOM   825  N NZ    . LYS   C 2 75  ? 182.335 207.752 225.561 1.00 63.58  ? 87  LYS   A NZ    1 
ATOM   826  N N     . ASP   C 2 76  ? 183.597 205.209 218.872 1.00 52.04  ? 88  ASP   A N     1 
ATOM   827  C CA    . ASP   C 2 76  ? 184.201 205.015 217.564 1.00 53.73  ? 88  ASP   A CA    1 
ATOM   828  C C     . ASP   C 2 76  ? 185.051 206.229 217.193 1.00 50.30  ? 88  ASP   A C     1 
ATOM   829  O O     . ASP   C 2 76  ? 184.674 207.367 217.489 1.00 48.60  ? 88  ASP   A O     1 
ATOM   830  C CB    . ASP   C 2 76  ? 183.126 204.775 216.507 1.00 53.70  ? 88  ASP   A CB    1 
ATOM   831  C CG    . ASP   C 2 76  ? 181.940 205.691 216.671 1.00 61.33  ? 88  ASP   A CG    1 
ATOM   832  O OD1   . ASP   C 2 76  ? 182.122 206.919 216.566 1.00 57.68  ? 88  ASP   A OD1   1 
ATOM   833  O OD2   . ASP   C 2 76  ? 180.824 205.185 216.906 1.00 71.52  ? 88  ASP   A OD2   1 
ATOM   834  N N     . PRO   C 2 77  ? 186.200 206.020 216.553 1.00 47.77  ? 89  PRO   A N     1 
ATOM   835  C CA    . PRO   C 2 77  ? 187.119 207.128 216.271 1.00 48.74  ? 89  PRO   A CA    1 
ATOM   836  C C     . PRO   C 2 77  ? 186.735 207.994 215.082 1.00 49.06  ? 89  PRO   A C     1 
ATOM   837  O O     . PRO   C 2 77  ? 187.550 208.817 214.659 1.00 49.44  ? 89  PRO   A O     1 
ATOM   838  C CB    . PRO   C 2 77  ? 188.442 206.396 215.999 1.00 51.82  ? 89  PRO   A CB    1 
ATOM   839  C CG    . PRO   C 2 77  ? 188.027 205.092 215.434 1.00 50.01  ? 89  PRO   A CG    1 
ATOM   840  C CD    . PRO   C 2 77  ? 186.751 204.720 216.131 1.00 46.47  ? 89  PRO   A CD    1 
ATOM   841  N N     . LYS   C 2 78  ? 185.533 207.845 214.528 1.00 49.82  ? 90  LYS   A N     1 
ATOM   842  C CA    . LYS   C 2 78  ? 185.112 208.644 213.384 1.00 45.37  ? 90  LYS   A CA    1 
ATOM   843  C C     . LYS   C 2 78  ? 183.945 209.566 213.704 1.00 43.36  ? 90  LYS   A C     1 
ATOM   844  O O     . LYS   C 2 78  ? 183.345 210.128 212.781 1.00 44.49  ? 90  LYS   A O     1 
ATOM   845  C CB    . LYS   C 2 78  ? 184.749 207.740 212.202 1.00 42.39  ? 90  LYS   A CB    1 
ATOM   846  C CG    . LYS   C 2 78  ? 185.716 206.598 211.978 1.00 43.92  ? 90  LYS   A CG    1 
ATOM   847  C CD    . LYS   C 2 78  ? 185.526 205.989 210.604 1.00 44.48  ? 90  LYS   A CD    1 
ATOM   848  C CE    . LYS   C 2 78  ? 186.740 206.238 209.729 1.00 43.91  ? 90  LYS   A CE    1 
ATOM   849  N NZ    . LYS   C 2 78  ? 186.615 205.587 208.398 1.00 50.57  ? 90  LYS   A NZ    1 
ATOM   850  N N     . LYS   C 2 79  ? 183.606 209.739 214.975 1.00 41.56  ? 91  LYS   A N     1 
ATOM   851  C CA    . LYS   C 2 79  ? 182.514 210.616 215.366 1.00 43.35  ? 91  LYS   A CA    1 
ATOM   852  C C     . LYS   C 2 79  ? 182.965 211.540 216.485 1.00 44.35  ? 91  LYS   A C     1 
ATOM   853  O O     . LYS   C 2 79  ? 183.688 211.126 217.394 1.00 47.17  ? 91  LYS   A O     1 
ATOM   854  C CB    . LYS   C 2 79  ? 181.289 209.816 215.811 1.00 43.51  ? 91  LYS   A CB    1 
ATOM   855  C CG    . LYS   C 2 79  ? 180.372 209.415 214.674 1.00 43.35  ? 91  LYS   A CG    1 
ATOM   856  C CD    . LYS   C 2 79  ? 179.615 208.143 214.996 1.00 39.38  ? 91  LYS   A CD    1 
ATOM   857  C CE    . LYS   C 2 79  ? 178.389 208.004 214.119 1.00 40.50  ? 91  LYS   A CE    1 
ATOM   858  N NZ    . LYS   C 2 79  ? 178.607 208.600 212.777 1.00 42.97  ? 91  LYS   A NZ    1 
ATOM   859  N N     . THR   C 2 80  ? 182.533 212.790 216.407 1.00 43.64  ? 92  THR   A N     1 
ATOM   860  C CA    . THR   C 2 80  ? 182.763 213.795 217.432 1.00 41.02  ? 92  THR   A CA    1 
ATOM   861  C C     . THR   C 2 80  ? 181.423 214.234 218.004 1.00 45.10  ? 92  THR   A C     1 
ATOM   862  O O     . THR   C 2 80  ? 180.360 213.797 217.560 1.00 50.70  ? 92  THR   A O     1 
ATOM   863  C CB    . THR   C 2 80  ? 183.527 214.996 216.871 1.00 42.55  ? 92  THR   A CB    1 
ATOM   864  O OG1   . THR   C 2 80  ? 183.085 215.264 215.535 1.00 44.62  ? 92  THR   A OG1   1 
ATOM   865  C CG2   . THR   C 2 80  ? 185.009 214.722 216.863 1.00 46.09  ? 92  THR   A CG2   1 
ATOM   866  N N     . GLY   C 2 81  ? 181.478 215.109 218.998 1.00 42.36  ? 93  GLY   A N     1 
ATOM   867  C CA    . GLY   C 2 81  ? 180.261 215.611 219.596 1.00 44.65  ? 93  GLY   A CA    1 
ATOM   868  C C     . GLY   C 2 81  ? 180.555 216.347 220.885 1.00 45.77  ? 93  GLY   A C     1 
ATOM   869  O O     . GLY   C 2 81  ? 181.705 216.661 221.199 1.00 49.61  ? 93  GLY   A O     1 
ATOM   870  N N     . GLY   C 2 82  ? 179.483 216.616 221.622 1.00 40.61  ? 94  GLY   A N     1 
ATOM   871  C CA    . GLY   C 2 82  ? 179.561 217.330 222.871 1.00 41.03  ? 94  GLY   A CA    1 
ATOM   872  C C     . GLY   C 2 82  ? 178.189 217.763 223.340 1.00 45.53  ? 94  GLY   A C     1 
ATOM   873  O O     . GLY   C 2 82  ? 177.191 217.609 222.630 1.00 47.59  ? 94  GLY   A O     1 
ATOM   874  N N     . PRO   C 2 83  ? 178.110 218.309 224.551 1.00 48.89  ? 95  PRO   A N     1 
ATOM   875  C CA    . PRO   C 2 83  ? 176.804 218.698 225.095 1.00 49.49  ? 95  PRO   A CA    1 
ATOM   876  C C     . PRO   C 2 83  ? 176.174 219.834 224.302 1.00 49.13  ? 95  PRO   A C     1 
ATOM   877  O O     . PRO   C 2 83  ? 176.830 220.822 223.968 1.00 50.76  ? 95  PRO   A O     1 
ATOM   878  C CB    . PRO   C 2 83  ? 177.130 219.137 226.528 1.00 51.25  ? 95  PRO   A CB    1 
ATOM   879  C CG    . PRO   C 2 83  ? 178.492 218.589 226.813 1.00 45.82  ? 95  PRO   A CG    1 
ATOM   880  C CD    . PRO   C 2 83  ? 179.202 218.552 225.504 1.00 47.35  ? 95  PRO   A CD    1 
ATOM   881  N N     . ILE   C 2 84  ? 174.884 219.689 224.020 1.00 48.83  ? 96  ILE   A N     1 
ATOM   882  C CA    . ILE   C 2 84  ? 174.091 220.719 223.358 1.00 48.64  ? 96  ILE   A CA    1 
ATOM   883  C C     . ILE   C 2 84  ? 172.950 221.077 224.296 1.00 48.92  ? 96  ILE   A C     1 
ATOM   884  O O     . ILE   C 2 84  ? 172.131 220.218 224.645 1.00 51.95  ? 96  ILE   A O     1 
ATOM   885  C CB    . ILE   C 2 84  ? 173.563 220.257 221.994 1.00 49.10  ? 96  ILE   A CB    1 
ATOM   886  C CG1   . ILE   C 2 84  ? 174.710 220.152 220.991 1.00 47.99  ? 96  ILE   A CG1   1 
ATOM   887  C CG2   . ILE   C 2 84  ? 172.501 221.214 221.485 1.00 46.52  ? 96  ILE   A CG2   1 
ATOM   888  C CD1   . ILE   C 2 84  ? 175.542 221.407 220.892 1.00 47.02  ? 96  ILE   A CD1   1 
ATOM   889  N N     . TYR   C 2 85  ? 172.892 222.339 224.706 1.00 46.73  ? 97  TYR   A N     1 
ATOM   890  C CA    . TYR   C 2 85  ? 171.912 222.791 225.685 1.00 47.80  ? 97  TYR   A CA    1 
ATOM   891  C C     . TYR   C 2 85  ? 170.764 223.470 224.949 1.00 49.51  ? 97  TYR   A C     1 
ATOM   892  O O     . TYR   C 2 85  ? 170.951 224.513 224.316 1.00 51.13  ? 97  TYR   A O     1 
ATOM   893  C CB    . TYR   C 2 85  ? 172.566 223.724 226.700 1.00 44.90  ? 97  TYR   A CB    1 
ATOM   894  C CG    . TYR   C 2 85  ? 173.778 223.117 227.373 1.00 46.85  ? 97  TYR   A CG    1 
ATOM   895  C CD1   . TYR   C 2 85  ? 175.026 223.160 226.767 1.00 45.91  ? 97  TYR   A CD1   1 
ATOM   896  C CD2   . TYR   C 2 85  ? 173.674 222.489 228.607 1.00 50.92  ? 97  TYR   A CD2   1 
ATOM   897  C CE1   . TYR   C 2 85  ? 176.132 222.605 227.370 1.00 46.92  ? 97  TYR   A CE1   1 
ATOM   898  C CE2   . TYR   C 2 85  ? 174.780 221.931 229.218 1.00 49.48  ? 97  TYR   A CE2   1 
ATOM   899  C CZ    . TYR   C 2 85  ? 176.006 221.992 228.593 1.00 49.45  ? 97  TYR   A CZ    1 
ATOM   900  O OH    . TYR   C 2 85  ? 177.115 221.439 229.188 1.00 52.14  ? 97  TYR   A OH    1 
ATOM   901  N N     . ARG   C 2 86  ? 169.578 222.878 225.034 1.00 48.86  ? 98  ARG   A N     1 
ATOM   902  C CA    . ARG   C 2 86  ? 168.389 223.383 224.363 1.00 48.30  ? 98  ARG   A CA    1 
ATOM   903  C C     . ARG   C 2 86  ? 167.334 223.746 225.397 1.00 49.81  ? 98  ARG   A C     1 
ATOM   904  O O     . ARG   C 2 86  ? 167.136 223.013 226.371 1.00 51.12  ? 98  ARG   A O     1 
ATOM   905  C CB    . ARG   C 2 86  ? 167.838 222.350 223.378 1.00 47.34  ? 98  ARG   A CB    1 
ATOM   906  C CG    . ARG   C 2 86  ? 168.731 222.141 222.175 1.00 50.76  ? 98  ARG   A CG    1 
ATOM   907  C CD    . ARG   C 2 86  ? 168.132 221.154 221.201 1.00 51.64  ? 98  ARG   A CD    1 
ATOM   908  N NE    . ARG   C 2 86  ? 169.005 220.953 220.053 1.00 48.88  ? 98  ARG   A NE    1 
ATOM   909  C CZ    . ARG   C 2 86  ? 168.801 220.046 219.109 1.00 50.75  ? 98  ARG   A CZ    1 
ATOM   910  N NH1   . ARG   C 2 86  ? 167.754 219.239 219.142 1.00 56.02  ? 98  ARG   A NH1   1 
ATOM   911  N NH2   . ARG   C 2 86  ? 169.666 219.951 218.104 1.00 49.79  ? 98  ARG   A NH2   1 
ATOM   912  N N     . ARG   C 2 87  ? 166.666 224.877 225.186 1.00 50.81  ? 99  ARG   A N     1 
ATOM   913  C CA    . ARG   C 2 87  ? 165.644 225.366 226.104 1.00 50.44  ? 99  ARG   A CA    1 
ATOM   914  C C     . ARG   C 2 87  ? 164.285 224.868 225.628 1.00 55.78  ? 99  ARG   A C     1 
ATOM   915  O O     . ARG   C 2 87  ? 163.887 225.117 224.485 1.00 60.30  ? 99  ARG   A O     1 
ATOM   916  C CB    . ARG   C 2 87  ? 165.679 226.890 226.189 1.00 50.80  ? 99  ARG   A CB    1 
ATOM   917  C CG    . ARG   C 2 87  ? 164.324 227.536 226.410 1.00 52.26  ? 99  ARG   A CG    1 
ATOM   918  C CD    . ARG   C 2 87  ? 164.424 229.050 226.407 1.00 55.50  ? 99  ARG   A CD    1 
ATOM   919  N NE    . ARG   C 2 87  ? 164.724 229.569 227.735 1.00 56.51  ? 99  ARG   A NE    1 
ATOM   920  C CZ    . ARG   C 2 87  ? 165.023 230.833 227.996 1.00 48.61  ? 99  ARG   A CZ    1 
ATOM   921  N NH1   . ARG   C 2 87  ? 165.044 231.746 227.040 1.00 44.94  ? 99  ARG   A NH1   1 
ATOM   922  N NH2   . ARG   C 2 87  ? 165.299 231.191 229.246 1.00 46.63  ? 99  ARG   A NH2   1 
ATOM   923  N N     . VAL   C 2 88  ? 163.585 224.140 226.492 1.00 58.63  ? 100 VAL   A N     1 
ATOM   924  C CA    . VAL   C 2 88  ? 162.221 223.698 226.236 1.00 60.17  ? 100 VAL   A CA    1 
ATOM   925  C C     . VAL   C 2 88  ? 161.368 224.099 227.431 1.00 61.68  ? 100 VAL   A C     1 
ATOM   926  O O     . VAL   C 2 88  ? 161.855 224.097 228.567 1.00 66.81  ? 100 VAL   A O     1 
ATOM   927  C CB    . VAL   C 2 88  ? 162.141 222.183 225.979 1.00 66.55  ? 100 VAL   A CB    1 
ATOM   928  C CG1   . VAL   C 2 88  ? 160.765 221.804 225.457 1.00 74.92  ? 100 VAL   A CG1   1 
ATOM   929  C CG2   . VAL   C 2 88  ? 163.210 221.761 224.982 1.00 63.22  ? 100 VAL   A CG2   1 
ATOM   930  N N     . ASP   C 2 89  ? 160.125 224.510 227.151 1.00 60.47  ? 101 ASP   A N     1 
ATOM   931  C CA    . ASP   C 2 89  ? 159.125 224.955 228.137 1.00 61.80  ? 101 ASP   A CA    1 
ATOM   932  C C     . ASP   C 2 89  ? 159.750 225.717 229.307 1.00 65.34  ? 101 ASP   A C     1 
ATOM   933  O O     . ASP   C 2 89  ? 159.375 225.539 230.468 1.00 70.90  ? 101 ASP   A O     1 
ATOM   934  C CB    . ASP   C 2 89  ? 158.224 223.798 228.610 1.00 66.09  ? 101 ASP   A CB    1 
ATOM   935  C CG    . ASP   C 2 89  ? 158.886 222.849 229.599 1.00 79.15  ? 101 ASP   A CG    1 
ATOM   936  O OD1   . ASP   C 2 89  ? 160.096 222.601 229.521 1.00 76.54  ? 101 ASP   A OD1   1 
ATOM   937  O OD2   . ASP   C 2 89  ? 158.161 222.312 230.462 1.00 90.09  ? 101 ASP   A OD2   1 
ATOM   938  N N     . GLY   C 2 90  ? 160.698 226.598 228.990 1.00 60.11  ? 102 GLY   A N     1 
ATOM   939  C CA    . GLY   C 2 90  ? 161.284 227.485 229.975 1.00 50.51  ? 102 GLY   A CA    1 
ATOM   940  C C     . GLY   C 2 90  ? 162.549 226.978 230.633 1.00 53.99  ? 102 GLY   A C     1 
ATOM   941  O O     . GLY   C 2 90  ? 163.429 227.770 230.978 1.00 55.79  ? 102 GLY   A O     1 
ATOM   942  N N     . LYS   C 2 91  ? 162.660 225.668 230.815 1.00 56.56  ? 103 LYS   A N     1 
ATOM   943  C CA    . LYS   C 2 91  ? 163.811 225.092 231.489 1.00 52.85  ? 103 LYS   A CA    1 
ATOM   944  C C     . LYS   C 2 91  ? 164.830 224.584 230.477 1.00 53.41  ? 103 LYS   A C     1 
ATOM   945  O O     . LYS   C 2 91  ? 164.498 224.285 229.329 1.00 59.35  ? 103 LYS   A O     1 
ATOM   946  C CB    . LYS   C 2 91  ? 163.386 223.954 232.416 1.00 54.79  ? 103 LYS   A CB    1 
ATOM   947  C CG    . LYS   C 2 91  ? 163.141 224.388 233.851 1.00 61.19  ? 103 LYS   A CG    1 
ATOM   948  C CD    . LYS   C 2 91  ? 163.337 223.230 234.816 1.00 63.76  ? 103 LYS   A CD    1 
ATOM   949  C CE    . LYS   C 2 91  ? 162.396 222.071 234.517 1.00 66.98  ? 103 LYS   A CE    1 
ATOM   950  N NZ    . LYS   C 2 91  ? 161.066 222.530 234.032 1.00 67.17  ? 103 LYS   A NZ    1 
ATOM   951  N N     . TRP   C 2 92  ? 166.080 224.496 230.916 1.00 50.80  ? 104 TRP   A N     1 
ATOM   952  C CA    . TRP   C 2 92  ? 167.162 224.037 230.060 1.00 48.99  ? 104 TRP   A CA    1 
ATOM   953  C C     . TRP   C 2 92  ? 167.291 222.519 230.128 1.00 50.59  ? 104 TRP   A C     1 
ATOM   954  O O     . TRP   C 2 92  ? 166.825 221.872 231.068 1.00 54.64  ? 104 TRP   A O     1 
ATOM   955  C CB    . TRP   C 2 92  ? 168.479 224.701 230.455 1.00 46.74  ? 104 TRP   A CB    1 
ATOM   956  C CG    . TRP   C 2 92  ? 168.571 226.118 229.996 1.00 50.45  ? 104 TRP   A CG    1 
ATOM   957  C CD1   . TRP   C 2 92  ? 168.276 227.232 230.721 1.00 51.46  ? 104 TRP   A CD1   1 
ATOM   958  C CD2   . TRP   C 2 92  ? 168.969 226.577 228.700 1.00 49.69  ? 104 TRP   A CD2   1 
ATOM   959  N NE1   . TRP   C 2 92  ? 168.473 228.358 229.961 1.00 47.79  ? 104 TRP   A NE1   1 
ATOM   960  C CE2   . TRP   C 2 92  ? 168.899 227.982 228.716 1.00 46.12  ? 104 TRP   A CE2   1 
ATOM   961  C CE3   . TRP   C 2 92  ? 169.383 225.936 227.529 1.00 50.70  ? 104 TRP   A CE3   1 
ATOM   962  C CZ2   . TRP   C 2 92  ? 169.227 228.756 227.610 1.00 48.88  ? 104 TRP   A CZ2   1 
ATOM   963  C CZ3   . TRP   C 2 92  ? 169.707 226.708 226.431 1.00 52.85  ? 104 TRP   A CZ3   1 
ATOM   964  C CH2   . TRP   C 2 92  ? 169.628 228.103 226.479 1.00 53.27  ? 104 TRP   A CH2   1 
ATOM   965  N N     . ARG   C 2 93  ? 167.924 221.953 229.105 1.00 51.51  ? 105 ARG   A N     1 
ATOM   966  C CA    . ARG   C 2 93  ? 168.097 220.509 229.020 1.00 54.07  ? 105 ARG   A CA    1 
ATOM   967  C C     . ARG   C 2 93  ? 169.265 220.198 228.098 1.00 51.98  ? 105 ARG   A C     1 
ATOM   968  O O     . ARG   C 2 93  ? 169.380 220.784 227.018 1.00 55.36  ? 105 ARG   A O     1 
ATOM   969  C CB    . ARG   C 2 93  ? 166.820 219.830 228.517 1.00 55.74  ? 105 ARG   A CB    1 
ATOM   970  C CG    . ARG   C 2 93  ? 166.894 218.315 228.493 1.00 63.14  ? 105 ARG   A CG    1 
ATOM   971  C CD    . ARG   C 2 93  ? 165.710 217.637 227.788 1.00 65.83  ? 105 ARG   A CD    1 
ATOM   972  N NE    . ARG   C 2 93  ? 164.419 217.844 228.438 1.00 74.89  ? 105 ARG   A NE    1 
ATOM   973  C CZ    . ARG   C 2 93  ? 163.644 218.909 228.275 1.00 79.54  ? 105 ARG   A CZ    1 
ATOM   974  N NH1   . ARG   C 2 93  ? 163.958 219.871 227.425 1.00 74.18  ? 105 ARG   A NH1   1 
ATOM   975  N NH2   . ARG   C 2 93  ? 162.510 218.998 228.966 1.00 82.12  ? 105 ARG   A NH2   1 
ATOM   976  N N     . ARG   C 2 94  ? 170.123 219.279 228.528 1.00 49.99  ? 106 ARG   A N     1 
ATOM   977  C CA    . ARG   C 2 94  ? 171.317 218.920 227.778 1.00 49.42  ? 106 ARG   A CA    1 
ATOM   978  C C     . ARG   C 2 94  ? 171.110 217.613 227.025 1.00 49.03  ? 106 ARG   A C     1 
ATOM   979  O O     . ARG   C 2 94  ? 170.468 216.687 227.526 1.00 53.00  ? 106 ARG   A O     1 
ATOM   980  C CB    . ARG   C 2 94  ? 172.517 218.795 228.716 1.00 53.19  ? 106 ARG   A CB    1 
ATOM   981  C CG    . ARG   C 2 94  ? 173.841 218.619 228.007 1.00 52.93  ? 106 ARG   A CG    1 
ATOM   982  C CD    . ARG   C 2 94  ? 174.385 217.219 228.206 1.00 52.06  ? 106 ARG   A CD    1 
ATOM   983  N NE    . ARG   C 2 94  ? 174.361 216.817 229.605 1.00 51.27  ? 106 ARG   A NE    1 
ATOM   984  C CZ    . ARG   C 2 94  ? 175.159 217.310 230.543 1.00 55.32  ? 106 ARG   A CZ    1 
ATOM   985  N NH1   . ARG   C 2 94  ? 176.073 218.224 230.264 1.00 53.34  ? 106 ARG   A NH1   1 
ATOM   986  N NH2   . ARG   C 2 94  ? 175.038 216.870 231.793 1.00 60.78  ? 106 ARG   A NH2   1 
ATOM   987  N N     . GLU   C 2 95  ? 171.658 217.548 225.814 1.00 47.91  ? 107 GLU   A N     1 
ATOM   988  C CA    . GLU   C 2 95  ? 171.620 216.338 225.001 1.00 48.47  ? 107 GLU   A CA    1 
ATOM   989  C C     . GLU   C 2 95  ? 172.979 216.151 224.347 1.00 49.13  ? 107 GLU   A C     1 
ATOM   990  O O     . GLU   C 2 95  ? 173.540 217.101 223.796 1.00 52.04  ? 107 GLU   A O     1 
ATOM   991  C CB    . GLU   C 2 95  ? 170.517 216.414 223.943 1.00 47.24  ? 107 GLU   A CB    1 
ATOM   992  C CG    . GLU   C 2 95  ? 170.541 217.685 223.126 1.00 48.62  ? 107 GLU   A CG    1 
ATOM   993  C CD    . GLU   C 2 95  ? 170.139 217.455 221.691 1.00 58.54  ? 107 GLU   A CD    1 
ATOM   994  O OE1   . GLU   C 2 95  ? 169.477 216.435 221.414 1.00 60.49  ? 107 GLU   A OE1   1 
ATOM   995  O OE2   . GLU   C 2 95  ? 170.494 218.290 220.835 1.00 65.46  ? 107 GLU   A OE2   1 
ATOM   996  N N     . LEU   C 2 96  ? 173.514 214.936 224.418 1.00 45.55  ? 108 LEU   A N     1 
ATOM   997  C CA    . LEU   C 2 96  ? 174.785 214.643 223.768 1.00 44.78  ? 108 LEU   A CA    1 
ATOM   998  C C     . LEU   C 2 96  ? 174.558 214.407 222.281 1.00 47.57  ? 108 LEU   A C     1 
ATOM   999  O O     . LEU   C 2 96  ? 173.814 213.499 221.895 1.00 51.77  ? 108 LEU   A O     1 
ATOM   1000 C CB    . LEU   C 2 96  ? 175.446 213.427 224.413 1.00 42.39  ? 108 LEU   A CB    1 
ATOM   1001 C CG    . LEU   C 2 96  ? 176.844 213.078 223.904 1.00 40.85  ? 108 LEU   A CG    1 
ATOM   1002 C CD1   . LEU   C 2 96  ? 177.745 214.295 223.947 1.00 41.52  ? 108 LEU   A CD1   1 
ATOM   1003 C CD2   . LEU   C 2 96  ? 177.445 211.945 224.712 1.00 42.17  ? 108 LEU   A CD2   1 
ATOM   1004 N N     . ILE   C 2 97  ? 175.201 215.216 221.449 1.00 47.61  ? 109 ILE   A N     1 
ATOM   1005 C CA    . ILE   C 2 97  ? 175.066 215.113 220.005 1.00 45.65  ? 109 ILE   A CA    1 
ATOM   1006 C C     . ILE   C 2 97  ? 176.303 214.415 219.456 1.00 45.75  ? 109 ILE   A C     1 
ATOM   1007 O O     . ILE   C 2 97  ? 177.382 214.437 220.054 1.00 47.33  ? 109 ILE   A O     1 
ATOM   1008 C CB    . ILE   C 2 97  ? 174.859 216.494 219.346 1.00 45.58  ? 109 ILE   A CB    1 
ATOM   1009 C CG1   . ILE   C 2 97  ? 173.823 216.404 218.227 1.00 49.21  ? 109 ILE   A CG1   1 
ATOM   1010 C CG2   . ILE   C 2 97  ? 176.170 217.052 218.815 1.00 47.46  ? 109 ILE   A CG2   1 
ATOM   1011 C CD1   . ILE   C 2 97  ? 172.402 216.311 218.723 1.00 53.05  ? 109 ILE   A CD1   1 
ATOM   1012 N N     . LEU   C 2 98  ? 176.131 213.765 218.308 1.00 47.20  ? 110 LEU   A N     1 
ATOM   1013 C CA    . LEU   C 2 98  ? 177.205 213.006 217.676 1.00 47.01  ? 110 LEU   A CA    1 
ATOM   1014 C C     . LEU   C 2 98  ? 177.212 213.321 216.191 1.00 47.28  ? 110 LEU   A C     1 
ATOM   1015 O O     . LEU   C 2 98  ? 176.192 213.157 215.515 1.00 54.09  ? 110 LEU   A O     1 
ATOM   1016 C CB    . LEU   C 2 98  ? 177.027 211.502 217.904 1.00 44.57  ? 110 LEU   A CB    1 
ATOM   1017 C CG    . LEU   C 2 98  ? 177.578 210.916 219.204 1.00 42.64  ? 110 LEU   A CG    1 
ATOM   1018 C CD1   . LEU   C 2 98  ? 177.787 209.423 219.059 1.00 39.80  ? 110 LEU   A CD1   1 
ATOM   1019 C CD2   . LEU   C 2 98  ? 178.872 211.599 219.599 1.00 43.61  ? 110 LEU   A CD2   1 
ATOM   1020 N N     . TYR   C 2 99  ? 178.355 213.770 215.683 1.00 43.24  ? 111 TYR   A N     1 
ATOM   1021 C CA    . TYR   C 2 99  ? 178.501 214.134 214.283 1.00 44.25  ? 111 TYR   A CA    1 
ATOM   1022 C C     . TYR   C 2 99  ? 179.663 213.369 213.670 1.00 44.61  ? 111 TYR   A C     1 
ATOM   1023 O O     . TYR   C 2 99  ? 180.671 213.115 214.335 1.00 45.74  ? 111 TYR   A O     1 
ATOM   1024 C CB    . TYR   C 2 99  ? 178.734 215.638 214.127 1.00 45.96  ? 111 TYR   A CB    1 
ATOM   1025 C CG    . TYR   C 2 99  ? 177.507 216.411 213.710 1.00 48.60  ? 111 TYR   A CG    1 
ATOM   1026 C CD1   . TYR   C 2 99  ? 176.307 216.262 214.388 1.00 50.32  ? 111 TYR   A CD1   1 
ATOM   1027 C CD2   . TYR   C 2 99  ? 177.549 217.293 212.641 1.00 50.38  ? 111 TYR   A CD2   1 
ATOM   1028 C CE1   . TYR   C 2 99  ? 175.186 216.967 214.014 1.00 49.32  ? 111 TYR   A CE1   1 
ATOM   1029 C CE2   . TYR   C 2 99  ? 176.432 218.001 212.259 1.00 53.10  ? 111 TYR   A CE2   1 
ATOM   1030 C CZ    . TYR   C 2 99  ? 175.253 217.834 212.948 1.00 54.02  ? 111 TYR   A CZ    1 
ATOM   1031 O OH    . TYR   C 2 99  ? 174.137 218.540 212.569 1.00 63.68  ? 111 TYR   A OH    1 
ATOM   1032 N N     . ASP   C 2 100 ? 179.517 212.998 212.402 1.00 46.93  ? 112 ASP   A N     1 
ATOM   1033 C CA    . ASP   C 2 100 ? 180.626 212.402 211.671 1.00 44.54  ? 112 ASP   A CA    1 
ATOM   1034 C C     . ASP   C 2 100 ? 181.722 213.440 211.489 1.00 47.02  ? 112 ASP   A C     1 
ATOM   1035 O O     . ASP   C 2 100 ? 181.448 214.596 211.155 1.00 53.35  ? 112 ASP   A O     1 
ATOM   1036 C CB    . ASP   C 2 100 ? 180.154 211.880 210.315 1.00 42.11  ? 112 ASP   A CB    1 
ATOM   1037 C CG    . ASP   C 2 100 ? 179.505 210.516 210.410 1.00 44.71  ? 112 ASP   A CG    1 
ATOM   1038 O OD1   . ASP   C 2 100 ? 180.015 209.666 211.166 1.00 50.64  ? 112 ASP   A OD1   1 
ATOM   1039 O OD2   . ASP   C 2 100 ? 178.481 210.294 209.732 1.00 39.38  ? 112 ASP   A OD2   1 
ATOM   1040 N N     . LYS   C 2 101 ? 182.969 213.033 211.722 1.00 42.94  ? 113 LYS   A N     1 
ATOM   1041 C CA    . LYS   C 2 101 ? 184.072 213.982 211.624 1.00 42.87  ? 113 LYS   A CA    1 
ATOM   1042 C C     . LYS   C 2 101 ? 184.304 214.420 210.184 1.00 45.84  ? 113 LYS   A C     1 
ATOM   1043 O O     . LYS   C 2 101 ? 184.692 215.570 209.942 1.00 48.13  ? 113 LYS   A O     1 
ATOM   1044 C CB    . LYS   C 2 101 ? 185.335 213.371 212.222 1.00 41.70  ? 113 LYS   A CB    1 
ATOM   1045 C CG    . LYS   C 2 101 ? 185.197 213.089 213.702 1.00 43.89  ? 113 LYS   A CG    1 
ATOM   1046 C CD    . LYS   C 2 101 ? 186.263 212.145 214.205 1.00 41.02  ? 113 LYS   A CD    1 
ATOM   1047 C CE    . LYS   C 2 101 ? 187.385 212.908 214.861 1.00 39.64  ? 113 LYS   A CE    1 
ATOM   1048 N NZ    . LYS   C 2 101 ? 188.110 212.070 215.852 1.00 34.96  ? 113 LYS   A NZ    1 
ATOM   1049 N N     . GLU   C 2 102 ? 184.068 213.524 209.223 1.00 46.73  ? 114 GLU   A N     1 
ATOM   1050 C CA    . GLU   C 2 102 ? 184.114 213.923 207.821 1.00 47.79  ? 114 GLU   A CA    1 
ATOM   1051 C C     . GLU   C 2 102 ? 183.079 214.999 207.532 1.00 45.11  ? 114 GLU   A C     1 
ATOM   1052 O O     . GLU   C 2 102 ? 183.347 215.943 206.781 1.00 47.30  ? 114 GLU   A O     1 
ATOM   1053 C CB    . GLU   C 2 102 ? 183.894 212.708 206.918 1.00 50.42  ? 114 GLU   A CB    1 
ATOM   1054 C CG    . GLU   C 2 102 ? 185.167 212.089 206.346 1.00 56.83  ? 114 GLU   A CG    1 
ATOM   1055 C CD    . GLU   C 2 102 ? 185.930 213.005 205.395 1.00 72.44  ? 114 GLU   A CD    1 
ATOM   1056 O OE1   . GLU   C 2 102 ? 186.988 212.574 204.891 1.00 80.77  ? 114 GLU   A OE1   1 
ATOM   1057 O OE2   . GLU   C 2 102 ? 185.470 214.133 205.118 1.00 72.14  ? 114 GLU   A OE2   1 
ATOM   1058 N N     . GLU   C 2 103 ? 181.895 214.881 208.135 1.00 42.24  ? 115 GLU   A N     1 
ATOM   1059 C CA    . GLU   C 2 103 ? 180.865 215.897 207.954 1.00 42.76  ? 115 GLU   A CA    1 
ATOM   1060 C C     . GLU   C 2 103 ? 181.319 217.247 208.497 1.00 43.98  ? 115 GLU   A C     1 
ATOM   1061 O O     . GLU   C 2 103 ? 181.126 218.281 207.846 1.00 45.92  ? 115 GLU   A O     1 
ATOM   1062 C CB    . GLU   C 2 103 ? 179.572 215.448 208.633 1.00 43.80  ? 115 GLU   A CB    1 
ATOM   1063 C CG    . GLU   C 2 103 ? 178.436 216.446 208.549 1.00 47.03  ? 115 GLU   A CG    1 
ATOM   1064 C CD    . GLU   C 2 103 ? 177.641 216.307 207.269 1.00 53.87  ? 115 GLU   A CD    1 
ATOM   1065 O OE1   . GLU   C 2 103 ? 177.853 215.316 206.542 1.00 57.34  ? 115 GLU   A OE1   1 
ATOM   1066 O OE2   . GLU   C 2 103 ? 176.803 217.188 206.991 1.00 57.36  ? 115 GLU   A OE2   1 
ATOM   1067 N N     . ILE   C 2 104 ? 181.928 217.257 209.684 1.00 41.93  ? 116 ILE   A N     1 
ATOM   1068 C CA    . ILE   C 2 104 ? 182.382 218.513 210.276 1.00 42.56  ? 116 ILE   A CA    1 
ATOM   1069 C C     . ILE   C 2 104 ? 183.482 219.137 209.430 1.00 42.12  ? 116 ILE   A C     1 
ATOM   1070 O O     . ILE   C 2 104 ? 183.492 220.353 209.197 1.00 41.90  ? 116 ILE   A O     1 
ATOM   1071 C CB    . ILE   C 2 104 ? 182.841 218.288 211.727 1.00 43.91  ? 116 ILE   A CB    1 
ATOM   1072 C CG1   . ILE   C 2 104 ? 181.678 217.786 212.580 1.00 45.14  ? 116 ILE   A CG1   1 
ATOM   1073 C CG2   . ILE   C 2 104 ? 183.413 219.567 212.312 1.00 43.46  ? 116 ILE   A CG2   1 
ATOM   1074 C CD1   . ILE   C 2 104 ? 180.695 218.863 212.946 1.00 45.73  ? 116 ILE   A CD1   1 
ATOM   1075 N N     . ARG   C 2 105 ? 184.430 218.321 208.962 1.00 42.72  ? 117 ARG   A N     1 
ATOM   1076 C CA    . ARG   C 2 105 ? 185.481 218.844 208.098 1.00 42.03  ? 117 ARG   A CA    1 
ATOM   1077 C C     . ARG   C 2 105 ? 184.912 219.398 206.799 1.00 43.63  ? 117 ARG   A C     1 
ATOM   1078 O O     . ARG   C 2 105 ? 185.363 220.444 206.319 1.00 42.65  ? 117 ARG   A O     1 
ATOM   1079 C CB    . ARG   C 2 105 ? 186.521 217.759 207.818 1.00 41.40  ? 117 ARG   A CB    1 
ATOM   1080 C CG    . ARG   C 2 105 ? 187.474 217.531 208.979 1.00 43.32  ? 117 ARG   A CG    1 
ATOM   1081 C CD    . ARG   C 2 105 ? 188.704 216.739 208.572 1.00 44.40  ? 117 ARG   A CD    1 
ATOM   1082 N NE    . ARG   C 2 105 ? 188.364 215.413 208.077 1.00 42.25  ? 117 ARG   A NE    1 
ATOM   1083 C CZ    . ARG   C 2 105 ? 188.046 214.389 208.855 1.00 45.56  ? 117 ARG   A CZ    1 
ATOM   1084 N NH1   . ARG   C 2 105 ? 188.024 214.503 210.172 1.00 45.66  ? 117 ARG   A NH1   1 
ATOM   1085 N NH2   . ARG   C 2 105 ? 187.745 213.220 208.299 1.00 53.93  ? 117 ARG   A NH2   1 
ATOM   1086 N N     . ARG   C 2 106 ? 183.913 218.724 206.227 1.00 44.69  ? 118 ARG   A N     1 
ATOM   1087 C CA    . ARG   C 2 106 ? 183.299 219.213 205.000 1.00 40.81  ? 118 ARG   A CA    1 
ATOM   1088 C C     . ARG   C 2 106 ? 182.581 220.538 205.229 1.00 41.52  ? 118 ARG   A C     1 
ATOM   1089 O O     . ARG   C 2 106 ? 182.673 221.450 204.400 1.00 42.59  ? 118 ARG   A O     1 
ATOM   1090 C CB    . ARG   C 2 106 ? 182.335 218.164 204.449 1.00 39.88  ? 118 ARG   A CB    1 
ATOM   1091 C CG    . ARG   C 2 106 ? 181.617 218.592 203.191 1.00 43.43  ? 118 ARG   A CG    1 
ATOM   1092 C CD    . ARG   C 2 106 ? 180.459 217.669 202.871 1.00 43.13  ? 118 ARG   A CD    1 
ATOM   1093 N NE    . ARG   C 2 106 ? 179.301 217.926 203.716 1.00 46.41  ? 118 ARG   A NE    1 
ATOM   1094 C CZ    . ARG   C 2 106 ? 178.493 218.969 203.585 1.00 47.99  ? 118 ARG   A CZ    1 
ATOM   1095 N NH1   . ARG   C 2 106 ? 178.696 219.889 202.656 1.00 44.59  ? 118 ARG   A NH1   1 
ATOM   1096 N NH2   . ARG   C 2 106 ? 177.454 219.092 204.405 1.00 46.44  ? 118 ARG   A NH2   1 
ATOM   1097 N N     . ILE   C 2 107 ? 181.869 220.665 206.351 1.00 41.45  ? 119 ILE   A N     1 
ATOM   1098 C CA    . ILE   C 2 107 ? 181.183 221.918 206.660 1.00 42.27  ? 119 ILE   A CA    1 
ATOM   1099 C C     . ILE   C 2 107 ? 182.191 223.045 206.847 1.00 43.25  ? 119 ILE   A C     1 
ATOM   1100 O O     . ILE   C 2 107 ? 182.006 224.157 206.334 1.00 44.31  ? 119 ILE   A O     1 
ATOM   1101 C CB    . ILE   C 2 107 ? 180.290 221.748 207.903 1.00 39.85  ? 119 ILE   A CB    1 
ATOM   1102 C CG1   . ILE   C 2 107 ? 179.174 220.741 207.628 1.00 43.17  ? 119 ILE   A CG1   1 
ATOM   1103 C CG2   . ILE   C 2 107 ? 179.691 223.079 208.313 1.00 43.80  ? 119 ILE   A CG2   1 
ATOM   1104 C CD1   . ILE   C 2 107 ? 178.243 220.538 208.795 1.00 45.92  ? 119 ILE   A CD1   1 
ATOM   1105 N N     . TRP   C 2 108 ? 183.276 222.774 207.577 1.00 43.15  ? 120 TRP   A N     1 
ATOM   1106 C CA    . TRP   C 2 108 ? 184.297 223.792 207.790 1.00 43.18  ? 120 TRP   A CA    1 
ATOM   1107 C C     . TRP   C 2 108 ? 184.928 224.227 206.475 1.00 45.66  ? 120 TRP   A C     1 
ATOM   1108 O O     . TRP   C 2 108 ? 185.132 225.423 206.240 1.00 47.27  ? 120 TRP   A O     1 
ATOM   1109 C CB    . TRP   C 2 108 ? 185.368 223.272 208.747 1.00 44.22  ? 120 TRP   A CB    1 
ATOM   1110 C CG    . TRP   C 2 108 ? 186.499 224.226 208.940 1.00 46.35  ? 120 TRP   A CG    1 
ATOM   1111 C CD1   . TRP   C 2 108 ? 187.720 224.182 208.338 1.00 47.21  ? 120 TRP   A CD1   1 
ATOM   1112 C CD2   . TRP   C 2 108 ? 186.515 225.375 209.793 1.00 47.22  ? 120 TRP   A CD2   1 
ATOM   1113 N NE1   . TRP   C 2 108 ? 188.497 225.229 208.764 1.00 48.19  ? 120 TRP   A NE1   1 
ATOM   1114 C CE2   . TRP   C 2 108 ? 187.779 225.976 209.660 1.00 47.17  ? 120 TRP   A CE2   1 
ATOM   1115 C CE3   . TRP   C 2 108 ? 185.583 225.952 210.659 1.00 49.45  ? 120 TRP   A CE3   1 
ATOM   1116 C CZ2   . TRP   C 2 108 ? 188.134 227.126 210.356 1.00 48.64  ? 120 TRP   A CZ2   1 
ATOM   1117 C CZ3   . TRP   C 2 108 ? 185.938 227.091 211.349 1.00 50.28  ? 120 TRP   A CZ3   1 
ATOM   1118 C CH2   . TRP   C 2 108 ? 187.201 227.667 211.195 1.00 49.15  ? 120 TRP   A CH2   1 
ATOM   1119 N N     . ARG   C 2 109 ? 185.246 223.269 205.603 1.00 44.89  ? 121 ARG   A N     1 
ATOM   1120 C CA    . ARG   C 2 109 ? 185.857 223.616 204.327 1.00 42.91  ? 121 ARG   A CA    1 
ATOM   1121 C C     . ARG   C 2 109 ? 184.891 224.392 203.442 1.00 43.39  ? 121 ARG   A C     1 
ATOM   1122 O O     . ARG   C 2 109 ? 185.292 225.351 202.772 1.00 46.95  ? 121 ARG   A O     1 
ATOM   1123 C CB    . ARG   C 2 109 ? 186.352 222.353 203.628 1.00 41.53  ? 121 ARG   A CB    1 
ATOM   1124 C CG    . ARG   C 2 109 ? 187.797 222.027 203.945 1.00 42.40  ? 121 ARG   A CG    1 
ATOM   1125 C CD    . ARG   C 2 109 ? 188.222 220.707 203.343 1.00 40.52  ? 121 ARG   A CD    1 
ATOM   1126 N NE    . ARG   C 2 109 ? 189.396 220.167 204.019 1.00 40.01  ? 121 ARG   A NE    1 
ATOM   1127 C CZ    . ARG   C 2 109 ? 189.487 218.931 204.484 1.00 41.98  ? 121 ARG   A CZ    1 
ATOM   1128 N NH1   . ARG   C 2 109 ? 188.488 218.073 204.363 1.00 45.03  ? 121 ARG   A NH1   1 
ATOM   1129 N NH2   . ARG   C 2 109 ? 190.607 218.544 205.084 1.00 40.12  ? 121 ARG   A NH2   1 
ATOM   1130 N N     . GLN   C 2 110 ? 183.613 224.007 203.435 1.00 41.84  ? 122 GLN   A N     1 
ATOM   1131 C CA    . GLN   C 2 110 ? 182.630 224.723 202.630 1.00 43.48  ? 122 GLN   A CA    1 
ATOM   1132 C C     . GLN   C 2 110 ? 182.444 226.149 203.132 1.00 46.87  ? 122 GLN   A C     1 
ATOM   1133 O O     . GLN   C 2 110 ? 182.240 227.074 202.337 1.00 50.48  ? 122 GLN   A O     1 
ATOM   1134 C CB    . GLN   C 2 110 ? 181.302 223.966 202.634 1.00 44.28  ? 122 GLN   A CB    1 
ATOM   1135 C CG    . GLN   C 2 110 ? 180.068 224.849 202.609 1.00 47.61  ? 122 GLN   A CG    1 
ATOM   1136 C CD    . GLN   C 2 110 ? 178.820 224.089 202.216 1.00 52.87  ? 122 GLN   A CD    1 
ATOM   1137 O OE1   . GLN   C 2 110 ? 178.707 222.891 202.465 1.00 53.95  ? 122 GLN   A OE1   1 
ATOM   1138 N NE2   . GLN   C 2 110 ? 177.876 224.784 201.596 1.00 54.22  ? 122 GLN   A NE2   1 
ATOM   1139 N N     . ALA   C 2 111 ? 182.518 226.347 204.450 1.00 46.96  ? 123 ALA   A N     1 
ATOM   1140 C CA    . ALA   C 2 111 ? 182.384 227.691 205.001 1.00 44.88  ? 123 ALA   A CA    1 
ATOM   1141 C C     . ALA   C 2 111 ? 183.527 228.595 204.555 1.00 47.20  ? 123 ALA   A C     1 
ATOM   1142 O O     . ALA   C 2 111 ? 183.317 229.779 204.271 1.00 47.55  ? 123 ALA   A O     1 
ATOM   1143 C CB    . ALA   C 2 111 ? 182.316 227.627 206.523 1.00 45.42  ? 123 ALA   A CB    1 
ATOM   1144 N N     . ASN   C 2 112 ? 184.745 228.058 204.487 1.00 47.44  ? 124 ASN   A N     1 
ATOM   1145 C CA    . ASN   C 2 112 ? 185.916 228.835 204.099 1.00 48.04  ? 124 ASN   A CA    1 
ATOM   1146 C C     . ASN   C 2 112 ? 186.211 228.755 202.608 1.00 50.21  ? 124 ASN   A C     1 
ATOM   1147 O O     . ASN   C 2 112 ? 187.371 228.908 202.203 1.00 55.90  ? 124 ASN   A O     1 
ATOM   1148 C CB    . ASN   C 2 112 ? 187.133 228.387 204.907 1.00 47.75  ? 124 ASN   A CB    1 
ATOM   1149 C CG    . ASN   C 2 112 ? 186.869 228.382 206.392 1.00 54.57  ? 124 ASN   A CG    1 
ATOM   1150 O OD1   . ASN   C 2 112 ? 185.926 229.008 206.869 1.00 61.36  ? 124 ASN   A OD1   1 
ATOM   1151 N ND2   . ASN   C 2 112 ? 187.698 227.667 207.135 1.00 53.29  ? 124 ASN   A ND2   1 
ATOM   1152 N N     . ASN   C 2 113 ? 185.191 228.518 201.781 1.00 49.41  ? 125 ASN   A N     1 
ATOM   1153 C CA    . ASN   C 2 113 ? 185.343 228.437 200.329 1.00 51.25  ? 125 ASN   A CA    1 
ATOM   1154 C C     . ASN   C 2 113 ? 186.341 227.350 199.934 1.00 53.27  ? 125 ASN   A C     1 
ATOM   1155 O O     . ASN   C 2 113 ? 187.314 227.596 199.218 1.00 57.54  ? 125 ASN   A O     1 
ATOM   1156 C CB    . ASN   C 2 113 ? 185.744 229.792 199.740 1.00 51.63  ? 125 ASN   A CB    1 
ATOM   1157 C CG    . ASN   C 2 113 ? 184.604 230.782 199.728 1.00 52.45  ? 125 ASN   A CG    1 
ATOM   1158 O OD1   . ASN   C 2 113 ? 183.542 230.529 200.296 1.00 55.26  ? 125 ASN   A OD1   1 
ATOM   1159 N ND2   . ASN   C 2 113 ? 184.815 231.919 199.079 1.00 51.81  ? 125 ASN   A ND2   1 
ATOM   1160 N N     . GLY   C 2 114 ? 186.094 226.135 200.415 1.00 49.13  ? 126 GLY   A N     1 
ATOM   1161 C CA    . GLY   C 2 114 ? 186.909 225.002 200.026 1.00 48.27  ? 126 GLY   A CA    1 
ATOM   1162 C C     . GLY   C 2 114 ? 188.341 225.046 200.502 1.00 52.10  ? 126 GLY   A C     1 
ATOM   1163 O O     . GLY   C 2 114 ? 189.176 224.302 199.985 1.00 60.28  ? 126 GLY   A O     1 
ATOM   1164 N N     . ASP   C 2 115 ? 188.653 225.895 201.474 1.00 50.80  ? 127 ASP   A N     1 
ATOM   1165 C CA    . ASP   C 2 115 ? 190.005 226.041 201.984 1.00 51.62  ? 127 ASP   A CA    1 
ATOM   1166 C C     . ASP   C 2 115 ? 190.102 225.462 203.389 1.00 51.79  ? 127 ASP   A C     1 
ATOM   1167 O O     . ASP   C 2 115 ? 189.146 225.514 204.168 1.00 53.62  ? 127 ASP   A O     1 
ATOM   1168 C CB    . ASP   C 2 115 ? 190.431 227.510 201.996 1.00 55.96  ? 127 ASP   A CB    1 
ATOM   1169 C CG    . ASP   C 2 115 ? 191.893 227.694 201.657 1.00 66.88  ? 127 ASP   A CG    1 
ATOM   1170 O OD1   . ASP   C 2 115 ? 192.530 226.716 201.215 1.00 68.07  ? 127 ASP   A OD1   1 
ATOM   1171 O OD2   . ASP   C 2 115 ? 192.408 228.818 201.832 1.00 75.11  ? 127 ASP   A OD2   1 
ATOM   1172 N N     . ASP   C 2 116 ? 191.271 224.899 203.703 1.00 50.15  ? 128 ASP   A N     1 
ATOM   1173 C CA    . ASP   C 2 116 ? 191.490 224.331 205.029 1.00 50.27  ? 128 ASP   A CA    1 
ATOM   1174 C C     . ASP   C 2 116 ? 191.394 225.405 206.106 1.00 50.78  ? 128 ASP   A C     1 
ATOM   1175 O O     . ASP   C 2 116 ? 190.654 225.254 207.084 1.00 49.57  ? 128 ASP   A O     1 
ATOM   1176 C CB    . ASP   C 2 116 ? 192.851 223.638 205.082 1.00 49.06  ? 128 ASP   A CB    1 
ATOM   1177 C CG    . ASP   C 2 116 ? 192.798 222.218 204.569 1.00 55.22  ? 128 ASP   A CG    1 
ATOM   1178 O OD1   . ASP   C 2 116 ? 191.823 221.872 203.873 1.00 57.91  ? 128 ASP   A OD1   1 
ATOM   1179 O OD2   . ASP   C 2 116 ? 193.734 221.445 204.863 1.00 58.18  ? 128 ASP   A OD2   1 
ATOM   1180 N N     . ALA   C 2 117 ? 192.134 226.499 205.934 1.00 51.39  ? 129 ALA   A N     1 
ATOM   1181 C CA    . ALA   C 2 117 ? 192.120 227.640 206.848 1.00 45.31  ? 129 ALA   A CA    1 
ATOM   1182 C C     . ALA   C 2 117 ? 192.404 227.207 208.286 1.00 44.73  ? 129 ALA   A C     1 
ATOM   1183 O O     . ALA   C 2 117 ? 191.561 227.303 209.179 1.00 46.28  ? 129 ALA   A O     1 
ATOM   1184 C CB    . ALA   C 2 117 ? 190.796 228.402 206.753 1.00 45.21  ? 129 ALA   A CB    1 
ATOM   1185 N N     . THR   C 2 118 ? 193.623 226.707 208.492 1.00 42.69  ? 130 THR   A N     1 
ATOM   1186 C CA    . THR   C 2 118 ? 194.068 226.360 209.835 1.00 44.59  ? 130 THR   A CA    1 
ATOM   1187 C C     . THR   C 2 118 ? 194.216 227.583 210.732 1.00 46.34  ? 130 THR   A C     1 
ATOM   1188 O O     . THR   C 2 118 ? 194.280 227.437 211.959 1.00 47.53  ? 130 THR   A O     1 
ATOM   1189 C CB    . THR   C 2 118 ? 195.389 225.595 209.765 1.00 44.27  ? 130 THR   A CB    1 
ATOM   1190 O OG1   . THR   C 2 118 ? 196.378 226.408 209.123 1.00 49.92  ? 130 THR   A OG1   1 
ATOM   1191 C CG2   . THR   C 2 118 ? 195.212 224.310 208.975 1.00 40.45  ? 130 THR   A CG2   1 
ATOM   1192 N N     . ALA   C 2 119 ? 194.269 228.784 210.148 1.00 42.16  ? 131 ALA   A N     1 
ATOM   1193 C CA    . ALA   C 2 119 ? 194.338 230.001 210.949 1.00 42.05  ? 131 ALA   A CA    1 
ATOM   1194 C C     . ALA   C 2 119 ? 193.086 230.177 211.800 1.00 45.34  ? 131 ALA   A C     1 
ATOM   1195 O O     . ALA   C 2 119 ? 193.169 230.595 212.960 1.00 45.70  ? 131 ALA   A O     1 
ATOM   1196 C CB    . ALA   C 2 119 ? 194.546 231.213 210.043 1.00 39.88  ? 131 ALA   A CB    1 
ATOM   1197 N N     . GLY   C 2 120 ? 191.915 229.871 211.240 1.00 43.24  ? 132 GLY   A N     1 
ATOM   1198 C CA    . GLY   C 2 120 ? 190.693 229.947 212.024 1.00 41.63  ? 132 GLY   A CA    1 
ATOM   1199 C C     . GLY   C 2 120 ? 190.686 228.970 213.183 1.00 43.66  ? 132 GLY   A C     1 
ATOM   1200 O O     . GLY   C 2 120 ? 190.264 229.309 214.293 1.00 45.43  ? 132 GLY   A O     1 
ATOM   1201 N N     . LEU   C 2 121 ? 191.158 227.746 212.943 1.00 45.03  ? 133 LEU   A N     1 
ATOM   1202 C CA    . LEU   C 2 121 ? 191.254 226.769 214.021 1.00 44.80  ? 133 LEU   A CA    1 
ATOM   1203 C C     . LEU   C 2 121 ? 192.211 227.245 215.104 1.00 44.82  ? 133 LEU   A C     1 
ATOM   1204 O O     . LEU   C 2 121 ? 191.945 227.069 216.298 1.00 45.73  ? 133 LEU   A O     1 
ATOM   1205 C CB    . LEU   C 2 121 ? 191.697 225.416 213.470 1.00 45.76  ? 133 LEU   A CB    1 
ATOM   1206 C CG    . LEU   C 2 121 ? 190.849 224.818 212.350 1.00 44.49  ? 133 LEU   A CG    1 
ATOM   1207 C CD1   . LEU   C 2 121 ? 191.405 223.471 211.941 1.00 44.67  ? 133 LEU   A CD1   1 
ATOM   1208 C CD2   . LEU   C 2 121 ? 189.411 224.685 212.799 1.00 44.78  ? 133 LEU   A CD2   1 
ATOM   1209 N N     . THR   C 2 122 ? 193.333 227.846 214.705 1.00 45.35  ? 134 THR   A N     1 
ATOM   1210 C CA    . THR   C 2 122 ? 194.258 228.399 215.688 1.00 43.93  ? 134 THR   A CA    1 
ATOM   1211 C C     . THR   C 2 122 ? 193.599 229.516 216.491 1.00 43.52  ? 134 THR   A C     1 
ATOM   1212 O O     . THR   C 2 122 ? 193.823 229.636 217.698 1.00 44.99  ? 134 THR   A O     1 
ATOM   1213 C CB    . THR   C 2 122 ? 195.522 228.904 214.994 1.00 45.32  ? 134 THR   A CB    1 
ATOM   1214 O OG1   . THR   C 2 122 ? 196.088 227.847 214.211 1.00 51.24  ? 134 THR   A OG1   1 
ATOM   1215 C CG2   . THR   C 2 122 ? 196.544 229.357 216.016 1.00 44.35  ? 134 THR   A CG2   1 
ATOM   1216 N N     . HIS   C 2 123 ? 192.782 230.339 215.833 1.00 42.99  ? 135 HIS   A N     1 
ATOM   1217 C CA    . HIS   C 2 123 ? 192.047 231.389 216.534 1.00 42.20  ? 135 HIS   A CA    1 
ATOM   1218 C C     . HIS   C 2 123 ? 191.110 230.799 217.586 1.00 42.04  ? 135 HIS   A C     1 
ATOM   1219 O O     . HIS   C 2 123 ? 191.048 231.285 218.724 1.00 41.80  ? 135 HIS   A O     1 
ATOM   1220 C CB    . HIS   C 2 123 ? 191.267 232.218 215.513 1.00 44.25  ? 135 HIS   A CB    1 
ATOM   1221 C CG    . HIS   C 2 123 ? 190.523 233.378 216.098 1.00 44.74  ? 135 HIS   A CG    1 
ATOM   1222 N ND1   . HIS   C 2 123 ? 191.085 234.628 216.236 1.00 42.39  ? 135 HIS   A ND1   1 
ATOM   1223 C CD2   . HIS   C 2 123 ? 189.253 233.485 216.553 1.00 46.65  ? 135 HIS   A CD2   1 
ATOM   1224 C CE1   . HIS   C 2 123 ? 190.197 235.452 216.761 1.00 45.15  ? 135 HIS   A CE1   1 
ATOM   1225 N NE2   . HIS   C 2 123 ? 189.078 234.782 216.965 1.00 46.38  ? 135 HIS   A NE2   1 
ATOM   1226 N N     . MET   C 2 124 ? 190.383 229.740 217.221 1.00 43.18  ? 136 MET   A N     1 
ATOM   1227 C CA    . MET   C 2 124 ? 189.475 229.096 218.168 1.00 43.32  ? 136 MET   A CA    1 
ATOM   1228 C C     . MET   C 2 124 ? 190.247 228.487 219.336 1.00 44.49  ? 136 MET   A C     1 
ATOM   1229 O O     . MET   C 2 124 ? 189.830 228.590 220.500 1.00 46.20  ? 136 MET   A O     1 
ATOM   1230 C CB    . MET   C 2 124 ? 188.657 228.023 217.450 1.00 40.75  ? 136 MET   A CB    1 
ATOM   1231 C CG    . MET   C 2 124 ? 188.038 228.501 216.147 1.00 44.53  ? 136 MET   A CG    1 
ATOM   1232 S SD    . MET   C 2 124 ? 186.733 227.479 215.444 1.00 60.55  ? 136 MET   A SD    1 
ATOM   1233 C CE    . MET   C 2 124 ? 185.283 228.342 216.017 1.00 48.50  ? 136 MET   A CE    1 
ATOM   1234 N N     . MET   C 2 125 ? 191.383 227.852 219.039 1.00 41.73  ? 137 MET   A N     1 
ATOM   1235 C CA    . MET   C 2 125 ? 192.213 227.269 220.088 1.00 38.09  ? 137 MET   A CA    1 
ATOM   1236 C C     . MET   C 2 125 ? 192.759 228.341 221.020 1.00 40.70  ? 137 MET   A C     1 
ATOM   1237 O O     . MET   C 2 125 ? 192.859 228.123 222.232 1.00 42.69  ? 137 MET   A O     1 
ATOM   1238 C CB    . MET   C 2 125 ? 193.353 226.463 219.466 1.00 37.56  ? 137 MET   A CB    1 
ATOM   1239 C CG    . MET   C 2 125 ? 192.881 225.254 218.687 1.00 42.43  ? 137 MET   A CG    1 
ATOM   1240 S SD    . MET   C 2 125 ? 193.975 224.759 217.347 1.00 47.96  ? 137 MET   A SD    1 
ATOM   1241 C CE    . MET   C 2 125 ? 195.547 224.799 218.182 1.00 44.59  ? 137 MET   A CE    1 
ATOM   1242 N N     . ILE   C 2 126 ? 193.126 229.500 220.476 1.00 40.96  ? 138 ILE   A N     1 
ATOM   1243 C CA    . ILE   C 2 126 ? 193.645 230.575 221.313 1.00 39.29  ? 138 ILE   A CA    1 
ATOM   1244 C C     . ILE   C 2 126 ? 192.540 231.132 222.202 1.00 40.44  ? 138 ILE   A C     1 
ATOM   1245 O O     . ILE   C 2 126 ? 192.778 231.478 223.365 1.00 42.66  ? 138 ILE   A O     1 
ATOM   1246 C CB    . ILE   C 2 126 ? 194.294 231.667 220.444 1.00 40.91  ? 138 ILE   A CB    1 
ATOM   1247 C CG1   . ILE   C 2 126 ? 195.637 231.182 219.903 1.00 41.85  ? 138 ILE   A CG1   1 
ATOM   1248 C CG2   . ILE   C 2 126 ? 194.528 232.926 221.249 1.00 44.53  ? 138 ILE   A CG2   1 
ATOM   1249 C CD1   . ILE   C 2 126 ? 196.077 231.894 218.649 1.00 45.21  ? 138 ILE   A CD1   1 
ATOM   1250 N N     . TRP   C 2 127 ? 191.315 231.221 221.679 1.00 39.86  ? 139 TRP   A N     1 
ATOM   1251 C CA    . TRP   C 2 127 ? 190.196 231.625 222.528 1.00 40.12  ? 139 TRP   A CA    1 
ATOM   1252 C C     . TRP   C 2 127 ? 189.992 230.637 223.672 1.00 41.18  ? 139 TRP   A C     1 
ATOM   1253 O O     . TRP   C 2 127 ? 189.804 231.039 224.831 1.00 42.64  ? 139 TRP   A O     1 
ATOM   1254 C CB    . TRP   C 2 127 ? 188.924 231.762 221.688 1.00 41.27  ? 139 TRP   A CB    1 
ATOM   1255 C CG    . TRP   C 2 127 ? 187.656 231.348 222.386 1.00 42.83  ? 139 TRP   A CG    1 
ATOM   1256 C CD1   . TRP   C 2 127 ? 186.846 230.302 222.052 1.00 43.65  ? 139 TRP   A CD1   1 
ATOM   1257 C CD2   . TRP   C 2 127 ? 187.044 231.982 223.515 1.00 42.82  ? 139 TRP   A CD2   1 
ATOM   1258 N NE1   . TRP   C 2 127 ? 185.774 230.240 222.908 1.00 42.63  ? 139 TRP   A NE1   1 
ATOM   1259 C CE2   . TRP   C 2 127 ? 185.873 231.260 223.816 1.00 41.95  ? 139 TRP   A CE2   1 
ATOM   1260 C CE3   . TRP   C 2 127 ? 187.375 233.085 224.305 1.00 43.21  ? 139 TRP   A CE3   1 
ATOM   1261 C CZ2   . TRP   C 2 127 ? 185.033 231.606 224.870 1.00 40.41  ? 139 TRP   A CZ2   1 
ATOM   1262 C CZ3   . TRP   C 2 127 ? 186.541 233.426 225.350 1.00 44.97  ? 139 TRP   A CZ3   1 
ATOM   1263 C CH2   . TRP   C 2 127 ? 185.384 232.690 225.622 1.00 43.24  ? 139 TRP   A CH2   1 
ATOM   1264 N N     . HIS   C 2 128 ? 190.051 229.337 223.372 1.00 41.30  ? 140 HIS   A N     1 
ATOM   1265 C CA    . HIS   C 2 128 ? 189.910 228.335 224.425 1.00 39.00  ? 140 HIS   A CA    1 
ATOM   1266 C C     . HIS   C 2 128 ? 191.032 228.447 225.450 1.00 41.82  ? 140 HIS   A C     1 
ATOM   1267 O O     . HIS   C 2 128 ? 190.797 228.328 226.658 1.00 44.87  ? 140 HIS   A O     1 
ATOM   1268 C CB    . HIS   C 2 128 ? 189.889 226.932 223.823 1.00 36.66  ? 140 HIS   A CB    1 
ATOM   1269 C CG    . HIS   C 2 128 ? 188.655 226.635 223.035 1.00 38.32  ? 140 HIS   A CG    1 
ATOM   1270 N ND1   . HIS   C 2 128 ? 188.589 225.613 222.113 1.00 39.79  ? 140 HIS   A ND1   1 
ATOM   1271 C CD2   . HIS   C 2 128 ? 187.440 227.228 223.026 1.00 42.36  ? 140 HIS   A CD2   1 
ATOM   1272 C CE1   . HIS   C 2 128 ? 187.385 225.589 221.573 1.00 40.85  ? 140 HIS   A CE1   1 
ATOM   1273 N NE2   . HIS   C 2 128 ? 186.668 226.559 222.110 1.00 43.76  ? 140 HIS   A NE2   1 
ATOM   1274 N N     . SER   C 2 129 ? 192.262 228.664 224.983 1.00 41.47  ? 141 SER   A N     1 
ATOM   1275 C CA    . SER   C 2 129 ? 193.398 228.779 225.889 1.00 41.00  ? 141 SER   A CA    1 
ATOM   1276 C C     . SER   C 2 129 ? 193.270 230.006 226.780 1.00 41.22  ? 141 SER   A C     1 
ATOM   1277 O O     . SER   C 2 129 ? 193.604 229.955 227.968 1.00 43.41  ? 141 SER   A O     1 
ATOM   1278 C CB    . SER   C 2 129 ? 194.701 228.827 225.095 1.00 43.51  ? 141 SER   A CB    1 
ATOM   1279 O OG    . SER   C 2 129 ? 195.707 229.515 225.815 1.00 49.05  ? 141 SER   A OG    1 
ATOM   1280 N N     . ASN   C 2 130 ? 192.801 231.122 226.222 1.00 41.33  ? 142 ASN   A N     1 
ATOM   1281 C CA    . ASN   C 2 130 ? 192.584 232.317 227.030 1.00 42.48  ? 142 ASN   A CA    1 
ATOM   1282 C C     . ASN   C 2 130 ? 191.515 232.075 228.087 1.00 40.14  ? 142 ASN   A C     1 
ATOM   1283 O O     . ASN   C 2 130 ? 191.662 232.501 229.238 1.00 40.95  ? 142 ASN   A O     1 
ATOM   1284 C CB    . ASN   C 2 130 ? 192.205 233.498 226.139 1.00 43.31  ? 142 ASN   A CB    1 
ATOM   1285 C CG    . ASN   C 2 130 ? 193.378 234.032 225.345 1.00 44.18  ? 142 ASN   A CG    1 
ATOM   1286 O OD1   . ASN   C 2 130 ? 194.535 233.808 225.696 1.00 48.63  ? 142 ASN   A OD1   1 
ATOM   1287 N ND2   . ASN   C 2 130 ? 193.086 234.761 224.275 1.00 38.73  ? 142 ASN   A ND2   1 
ATOM   1288 N N     . LEU   C 2 131 ? 190.435 231.382 227.716 1.00 41.64  ? 143 LEU   A N     1 
ATOM   1289 C CA    . LEU   C 2 131 ? 189.410 231.045 228.701 1.00 42.07  ? 143 LEU   A CA    1 
ATOM   1290 C C     . LEU   C 2 131 ? 189.978 230.170 229.815 1.00 42.83  ? 143 LEU   A C     1 
ATOM   1291 O O     . LEU   C 2 131 ? 189.721 230.413 231.002 1.00 43.80  ? 143 LEU   A O     1 
ATOM   1292 C CB    . LEU   C 2 131 ? 188.236 230.348 228.017 1.00 41.79  ? 143 LEU   A CB    1 
ATOM   1293 C CG    . LEU   C 2 131 ? 187.063 229.948 228.911 1.00 40.81  ? 143 LEU   A CG    1 
ATOM   1294 C CD1   . LEU   C 2 131 ? 186.604 231.122 229.753 1.00 37.77  ? 143 LEU   A CD1   1 
ATOM   1295 C CD2   . LEU   C 2 131 ? 185.918 229.407 228.077 1.00 45.29  ? 143 LEU   A CD2   1 
ATOM   1296 N N     . ASN   C 2 132 ? 190.764 229.154 229.451 1.00 42.61  ? 144 ASN   A N     1 
ATOM   1297 C CA    . ASN   C 2 132 ? 191.336 228.264 230.455 1.00 41.52  ? 144 ASN   A CA    1 
ATOM   1298 C C     . ASN   C 2 132 ? 192.306 229.004 231.366 1.00 42.99  ? 144 ASN   A C     1 
ATOM   1299 O O     . ASN   C 2 132 ? 192.342 228.758 232.577 1.00 47.28  ? 144 ASN   A O     1 
ATOM   1300 C CB    . ASN   C 2 132 ? 192.031 227.085 229.776 1.00 42.63  ? 144 ASN   A CB    1 
ATOM   1301 C CG    . ASN   C 2 132 ? 191.063 226.001 229.361 1.00 45.72  ? 144 ASN   A CG    1 
ATOM   1302 O OD1   . ASN   C 2 132 ? 191.013 225.611 228.197 1.00 46.34  ? 144 ASN   A OD1   1 
ATOM   1303 N ND2   . ASN   C 2 132 ? 190.282 225.511 230.313 1.00 51.85  ? 144 ASN   A ND2   1 
ATOM   1304 N N     . ASP   C 2 133 ? 193.108 229.907 230.800 1.00 43.00  ? 145 ASP   A N     1 
ATOM   1305 C CA    . ASP   C 2 133 ? 194.033 230.692 231.609 1.00 42.69  ? 145 ASP   A CA    1 
ATOM   1306 C C     . ASP   C 2 133 ? 193.286 231.612 232.564 1.00 40.19  ? 145 ASP   A C     1 
ATOM   1307 O O     . ASP   C 2 133 ? 193.696 231.783 233.718 1.00 42.27  ? 145 ASP   A O     1 
ATOM   1308 C CB    . ASP   C 2 133 ? 194.965 231.502 230.709 1.00 44.51  ? 145 ASP   A CB    1 
ATOM   1309 C CG    . ASP   C 2 133 ? 195.935 230.631 229.942 1.00 49.26  ? 145 ASP   A CG    1 
ATOM   1310 O OD1   . ASP   C 2 133 ? 196.274 229.538 230.437 1.00 50.93  ? 145 ASP   A OD1   1 
ATOM   1311 O OD2   . ASP   C 2 133 ? 196.361 231.040 228.844 1.00 48.51  ? 145 ASP   A OD2   1 
ATOM   1312 N N     . ALA   C 2 134 ? 192.189 232.213 232.103 1.00 40.46  ? 146 ALA   A N     1 
ATOM   1313 C CA    . ALA   C 2 134 ? 191.414 233.097 232.961 1.00 42.55  ? 146 ALA   A CA    1 
ATOM   1314 C C     . ALA   C 2 134 ? 190.594 232.346 233.997 1.00 45.46  ? 146 ALA   A C     1 
ATOM   1315 O O     . ALA   C 2 134 ? 190.166 232.953 234.984 1.00 48.05  ? 146 ALA   A O     1 
ATOM   1316 C CB    . ALA   C 2 134 ? 190.486 233.973 232.117 1.00 44.18  ? 146 ALA   A CB    1 
ATOM   1317 N N     . THR   C 2 135 ? 190.366 231.046 233.804 1.00 46.82  ? 147 THR   A N     1 
ATOM   1318 C CA    . THR   C 2 135 ? 189.523 230.279 234.715 1.00 44.42  ? 147 THR   A CA    1 
ATOM   1319 C C     . THR   C 2 135 ? 190.331 229.471 235.727 1.00 43.06  ? 147 THR   A C     1 
ATOM   1320 O O     . THR   C 2 135 ? 190.109 229.591 236.935 1.00 44.66  ? 147 THR   A O     1 
ATOM   1321 C CB    . THR   C 2 135 ? 188.595 229.354 233.917 1.00 45.36  ? 147 THR   A CB    1 
ATOM   1322 O OG1   . THR   C 2 135 ? 187.776 230.138 233.044 1.00 49.52  ? 147 THR   A OG1   1 
ATOM   1323 C CG2   . THR   C 2 135 ? 187.703 228.568 234.855 1.00 45.88  ? 147 THR   A CG2   1 
ATOM   1324 N N     . TYR   C 2 136 ? 191.272 228.654 235.261 1.00 43.65  ? 148 TYR   A N     1 
ATOM   1325 C CA    . TYR   C 2 136 ? 191.908 227.648 236.098 1.00 42.50  ? 148 TYR   A CA    1 
ATOM   1326 C C     . TYR   C 2 136 ? 193.397 227.919 236.277 1.00 45.34  ? 148 TYR   A C     1 
ATOM   1327 O O     . TYR   C 2 136 ? 194.057 228.483 235.400 1.00 44.92  ? 148 TYR   A O     1 
ATOM   1328 C CB    . TYR   C 2 136 ? 191.706 226.252 235.507 1.00 41.71  ? 148 TYR   A CB    1 
ATOM   1329 C CG    . TYR   C 2 136 ? 190.258 225.832 235.446 1.00 44.83  ? 148 TYR   A CG    1 
ATOM   1330 C CD1   . TYR   C 2 136 ? 189.470 225.823 236.587 1.00 47.89  ? 148 TYR   A CD1   1 
ATOM   1331 C CD2   . TYR   C 2 136 ? 189.677 225.445 234.247 1.00 44.97  ? 148 TYR   A CD2   1 
ATOM   1332 C CE1   . TYR   C 2 136 ? 188.147 225.442 236.537 1.00 47.84  ? 148 TYR   A CE1   1 
ATOM   1333 C CE2   . TYR   C 2 136 ? 188.353 225.064 234.190 1.00 46.77  ? 148 TYR   A CE2   1 
ATOM   1334 C CZ    . TYR   C 2 136 ? 187.594 225.062 235.338 1.00 48.08  ? 148 TYR   A CZ    1 
ATOM   1335 O OH    . TYR   C 2 136 ? 186.275 224.683 235.285 1.00 46.19  ? 148 TYR   A OH    1 
ATOM   1336 N N     . GLN   C 2 137 ? 193.919 227.507 237.434 1.00 47.97  ? 149 GLN   A N     1 
ATOM   1337 C CA    . GLN   C 2 137 ? 195.338 227.598 237.760 1.00 45.58  ? 149 GLN   A CA    1 
ATOM   1338 C C     . GLN   C 2 137 ? 195.935 226.203 237.637 1.00 45.41  ? 149 GLN   A C     1 
ATOM   1339 O O     . GLN   C 2 137 ? 195.437 225.255 238.253 1.00 46.46  ? 149 GLN   A O     1 
ATOM   1340 C CB    . GLN   C 2 137 ? 195.566 228.126 239.174 1.00 45.96  ? 149 GLN   A CB    1 
ATOM   1341 C CG    . GLN   C 2 137 ? 195.263 229.582 239.419 1.00 46.74  ? 149 GLN   A CG    1 
ATOM   1342 C CD    . GLN   C 2 137 ? 195.584 229.964 240.850 1.00 48.49  ? 149 GLN   A CD    1 
ATOM   1343 O OE1   . GLN   C 2 137 ? 196.049 229.135 241.626 1.00 48.13  ? 149 GLN   A OE1   1 
ATOM   1344 N NE2   . GLN   C 2 137 ? 195.311 231.204 241.213 1.00 50.10  ? 149 GLN   A NE2   1 
ATOM   1345 N N     . ARG   C 2 138 ? 197.001 226.074 236.852 1.00 45.70  ? 150 ARG   A N     1 
ATOM   1346 C CA    . ARG   C 2 138 ? 197.732 224.810 236.777 1.00 51.43  ? 150 ARG   A CA    1 
ATOM   1347 C C     . ARG   C 2 138 ? 199.000 224.892 237.629 1.00 48.36  ? 150 ARG   A C     1 
ATOM   1348 O O     . ARG   C 2 138 ? 200.130 224.852 237.143 1.00 49.55  ? 150 ARG   A O     1 
ATOM   1349 C CB    . ARG   C 2 138 ? 198.037 224.452 235.330 1.00 53.08  ? 150 ARG   A CB    1 
ATOM   1350 C CG    . ARG   C 2 138 ? 198.303 225.632 234.430 1.00 50.52  ? 150 ARG   A CG    1 
ATOM   1351 C CD    . ARG   C 2 138 ? 197.959 225.267 233.003 1.00 52.56  ? 150 ARG   A CD    1 
ATOM   1352 N NE    . ARG   C 2 138 ? 198.970 224.395 232.418 1.00 56.68  ? 150 ARG   A NE    1 
ATOM   1353 C CZ    . ARG   C 2 138 ? 198.784 223.112 232.144 1.00 55.69  ? 150 ARG   A CZ    1 
ATOM   1354 N NH1   . ARG   C 2 138 ? 197.633 222.512 232.397 1.00 50.58  ? 150 ARG   A NH1   1 
ATOM   1355 N NH2   . ARG   C 2 138 ? 199.779 222.413 231.608 1.00 58.29  ? 150 ARG   A NH2   1 
ATOM   1356 N N     . THR   C 2 139 ? 198.783 225.010 238.940 1.00 47.50  ? 151 THR   A N     1 
ATOM   1357 C CA    . THR   C 2 139 ? 199.897 224.903 239.874 1.00 48.14  ? 151 THR   A CA    1 
ATOM   1358 C C     . THR   C 2 139 ? 200.356 223.460 240.014 1.00 47.96  ? 151 THR   A C     1 
ATOM   1359 O O     . THR   C 2 139 ? 201.505 223.208 240.389 1.00 49.56  ? 151 THR   A O     1 
ATOM   1360 C CB    . THR   C 2 139 ? 199.510 225.461 241.243 1.00 48.72  ? 151 THR   A CB    1 
ATOM   1361 O OG1   . THR   C 2 139 ? 198.506 224.628 241.831 1.00 51.25  ? 151 THR   A OG1   1 
ATOM   1362 C CG2   . THR   C 2 139 ? 198.966 226.871 241.105 1.00 49.57  ? 151 THR   A CG2   1 
ATOM   1363 N N     . ARG   C 2 140 ? 199.466 222.506 239.731 1.00 46.30  ? 152 ARG   A N     1 
ATOM   1364 C CA    . ARG   C 2 140 ? 199.834 221.096 239.799 1.00 47.44  ? 152 ARG   A CA    1 
ATOM   1365 C C     . ARG   C 2 140 ? 200.883 220.748 238.750 1.00 47.78  ? 152 ARG   A C     1 
ATOM   1366 O O     . ARG   C 2 140 ? 201.863 220.054 239.048 1.00 48.83  ? 152 ARG   A O     1 
ATOM   1367 C CB    . ARG   C 2 140 ? 198.583 220.236 239.627 1.00 48.97  ? 152 ARG   A CB    1 
ATOM   1368 C CG    . ARG   C 2 140 ? 198.841 218.786 239.287 1.00 55.28  ? 152 ARG   A CG    1 
ATOM   1369 C CD    . ARG   C 2 140 ? 197.534 218.062 238.993 1.00 62.30  ? 152 ARG   A CD    1 
ATOM   1370 N NE    . ARG   C 2 140 ? 196.613 218.109 240.124 1.00 62.69  ? 152 ARG   A NE    1 
ATOM   1371 C CZ    . ARG   C 2 140 ? 195.549 218.898 240.195 1.00 49.22  ? 152 ARG   A CZ    1 
ATOM   1372 N NH1   . ARG   C 2 140 ? 195.228 219.714 239.206 1.00 43.61  ? 152 ARG   A NH1   1 
ATOM   1373 N NH2   . ARG   C 2 140 ? 194.789 218.867 241.285 1.00 45.68  ? 152 ARG   A NH2   1 
ATOM   1374 N N     . ALA   C 2 141 ? 200.704 221.229 237.519 1.00 47.47  ? 153 ALA   A N     1 
ATOM   1375 C CA    . ALA   C 2 141 ? 201.719 221.009 236.496 1.00 43.92  ? 153 ALA   A CA    1 
ATOM   1376 C C     . ALA   C 2 141 ? 202.993 221.782 236.803 1.00 46.69  ? 153 ALA   A C     1 
ATOM   1377 O O     . ALA   C 2 141 ? 204.084 221.363 236.404 1.00 51.47  ? 153 ALA   A O     1 
ATOM   1378 C CB    . ALA   C 2 141 ? 201.179 221.394 235.122 1.00 41.09  ? 153 ALA   A CB    1 
ATOM   1379 N N     . LEU   C 2 142 ? 202.873 222.909 237.505 1.00 46.07  ? 154 LEU   A N     1 
ATOM   1380 C CA    . LEU   C 2 142 ? 204.051 223.663 237.916 1.00 43.68  ? 154 LEU   A CA    1 
ATOM   1381 C C     . LEU   C 2 142 ? 204.884 222.879 238.921 1.00 45.99  ? 154 LEU   A C     1 
ATOM   1382 O O     . LEU   C 2 142 ? 206.102 222.739 238.758 1.00 48.77  ? 154 LEU   A O     1 
ATOM   1383 C CB    . LEU   C 2 142 ? 203.628 225.006 238.509 1.00 45.88  ? 154 LEU   A CB    1 
ATOM   1384 C CG    . LEU   C 2 142 ? 203.376 226.147 237.531 1.00 48.31  ? 154 LEU   A CG    1 
ATOM   1385 C CD1   . LEU   C 2 142 ? 202.729 227.326 238.228 1.00 49.08  ? 154 LEU   A CD1   1 
ATOM   1386 C CD2   . LEU   C 2 142 ? 204.698 226.555 236.948 1.00 49.71  ? 154 LEU   A CD2   1 
ATOM   1387 N N     . VAL   C 2 143 ? 204.243 222.361 239.968 1.00 46.19  ? 155 VAL   A N     1 
ATOM   1388 C CA    . VAL   C 2 143 ? 204.977 221.637 240.999 1.00 46.94  ? 155 VAL   A CA    1 
ATOM   1389 C C     . VAL   C 2 143 ? 205.469 220.297 240.470 1.00 47.79  ? 155 VAL   A C     1 
ATOM   1390 O O     . VAL   C 2 143 ? 206.542 219.825 240.865 1.00 47.77  ? 155 VAL   A O     1 
ATOM   1391 C CB    . VAL   C 2 143 ? 204.109 221.476 242.264 1.00 48.77  ? 155 VAL   A CB    1 
ATOM   1392 C CG1   . VAL   C 2 143 ? 202.844 220.698 241.960 1.00 48.55  ? 155 VAL   A CG1   1 
ATOM   1393 C CG2   . VAL   C 2 143 ? 204.900 220.808 243.376 1.00 54.00  ? 155 VAL   A CG2   1 
ATOM   1394 N N     . ARG   C 2 144 ? 204.714 219.669 239.567 1.00 48.05  ? 156 ARG   A N     1 
ATOM   1395 C CA    . ARG   C 2 144 ? 205.133 218.382 239.023 1.00 48.12  ? 156 ARG   A CA    1 
ATOM   1396 C C     . ARG   C 2 144 ? 206.412 218.520 238.206 1.00 48.44  ? 156 ARG   A C     1 
ATOM   1397 O O     . ARG   C 2 144 ? 207.276 217.638 238.237 1.00 51.38  ? 156 ARG   A O     1 
ATOM   1398 C CB    . ARG   C 2 144 ? 204.004 217.783 238.185 1.00 48.60  ? 156 ARG   A CB    1 
ATOM   1399 C CG    . ARG   C 2 144 ? 204.404 216.608 237.318 1.00 49.32  ? 156 ARG   A CG    1 
ATOM   1400 C CD    . ARG   C 2 144 ? 203.178 215.855 236.832 1.00 47.50  ? 156 ARG   A CD    1 
ATOM   1401 N NE    . ARG   C 2 144 ? 202.841 214.742 237.711 1.00 49.89  ? 156 ARG   A NE    1 
ATOM   1402 C CZ    . ARG   C 2 144 ? 203.142 213.476 237.463 1.00 58.06  ? 156 ARG   A CZ    1 
ATOM   1403 N NH1   . ARG   C 2 144 ? 203.787 213.123 236.364 1.00 63.02  ? 156 ARG   A NH1   1 
ATOM   1404 N NH2   . ARG   C 2 144 ? 202.788 212.541 238.339 1.00 56.90  ? 156 ARG   A NH2   1 
ATOM   1405 N N     . THR   C 2 145 ? 206.557 219.626 237.483 1.00 47.03  ? 157 THR   A N     1 
ATOM   1406 C CA    . THR   C 2 145 ? 207.757 219.892 236.702 1.00 47.93  ? 157 THR   A CA    1 
ATOM   1407 C C     . THR   C 2 145 ? 208.858 220.562 237.514 1.00 48.40  ? 157 THR   A C     1 
ATOM   1408 O O     . THR   C 2 145 ? 209.931 220.833 236.968 1.00 50.83  ? 157 THR   A O     1 
ATOM   1409 C CB    . THR   C 2 145 ? 207.419 220.763 235.488 1.00 48.11  ? 157 THR   A CB    1 
ATOM   1410 O OG1   . THR   C 2 145 ? 206.737 221.946 235.920 1.00 52.32  ? 157 THR   A OG1   1 
ATOM   1411 C CG2   . THR   C 2 145 ? 206.534 220.004 234.516 1.00 45.28  ? 157 THR   A CG2   1 
ATOM   1412 N N     . GLY   C 2 146 ? 208.622 220.835 238.795 1.00 46.94  ? 158 GLY   A N     1 
ATOM   1413 C CA    . GLY   C 2 146 ? 209.617 221.446 239.646 1.00 46.00  ? 158 GLY   A CA    1 
ATOM   1414 C C     . GLY   C 2 146 ? 209.589 222.957 239.687 1.00 48.61  ? 158 GLY   A C     1 
ATOM   1415 O O     . GLY   C 2 146 ? 210.303 223.551 240.505 1.00 48.79  ? 158 GLY   A O     1 
ATOM   1416 N N     . MET   C 2 147 ? 208.795 223.598 238.838 1.00 49.43  ? 159 MET   A N     1 
ATOM   1417 C CA    . MET   C 2 147 ? 208.734 225.051 238.827 1.00 47.50  ? 159 MET   A CA    1 
ATOM   1418 C C     . MET   C 2 147 ? 207.964 225.566 240.038 1.00 47.08  ? 159 MET   A C     1 
ATOM   1419 O O     . MET   C 2 147 ? 207.092 224.888 240.585 1.00 51.70  ? 159 MET   A O     1 
ATOM   1420 C CB    . MET   C 2 147 ? 208.076 225.545 237.541 1.00 50.22  ? 159 MET   A CB    1 
ATOM   1421 C CG    . MET   C 2 147 ? 208.987 225.535 236.330 1.00 50.77  ? 159 MET   A CG    1 
ATOM   1422 S SD    . MET   C 2 147 ? 208.130 225.997 234.816 1.00 50.13  ? 159 MET   A SD    1 
ATOM   1423 C CE    . MET   C 2 147 ? 208.045 227.771 235.014 1.00 48.64  ? 159 MET   A CE    1 
ATOM   1424 N N     . ASP   C 2 148 ? 208.304 226.775 240.457 1.00 47.67  ? 160 ASP   A N     1 
ATOM   1425 C CA    . ASP   C 2 148 ? 207.618 227.400 241.580 1.00 46.98  ? 160 ASP   A CA    1 
ATOM   1426 C C     . ASP   C 2 148 ? 206.177 227.709 241.191 1.00 48.81  ? 160 ASP   A C     1 
ATOM   1427 O O     . ASP   C 2 148 ? 205.941 228.288 240.126 1.00 50.35  ? 160 ASP   A O     1 
ATOM   1428 C CB    . ASP   C 2 148 ? 208.345 228.681 241.987 1.00 44.82  ? 160 ASP   A CB    1 
ATOM   1429 C CG    . ASP   C 2 148 ? 208.156 229.030 243.445 1.00 48.96  ? 160 ASP   A CG    1 
ATOM   1430 O OD1   . ASP   C 2 148 ? 207.058 228.795 243.984 1.00 55.04  ? 160 ASP   A OD1   1 
ATOM   1431 O OD2   . ASP   C 2 148 ? 209.113 229.550 244.054 1.00 51.75  ? 160 ASP   A OD2   1 
ATOM   1432 N N     . PRO   C 2 149 ? 205.188 227.332 242.008 1.00 47.62  ? 161 PRO   A N     1 
ATOM   1433 C CA    . PRO   C 2 149 ? 203.802 227.721 241.709 1.00 47.09  ? 161 PRO   A CA    1 
ATOM   1434 C C     . PRO   C 2 149 ? 203.531 229.209 241.855 1.00 47.21  ? 161 PRO   A C     1 
ATOM   1435 O O     . PRO   C 2 149 ? 202.399 229.638 241.609 1.00 46.96  ? 161 PRO   A O     1 
ATOM   1436 C CB    . PRO   C 2 149 ? 202.985 226.905 242.722 1.00 46.41  ? 161 PRO   A CB    1 
ATOM   1437 C CG    . PRO   C 2 149 ? 203.943 226.569 243.807 1.00 48.14  ? 161 PRO   A CG    1 
ATOM   1438 C CD    . PRO   C 2 149 ? 205.265 226.390 243.134 1.00 45.61  ? 161 PRO   A CD    1 
ATOM   1439 N N     . ARG   C 2 150 ? 204.524 230.011 242.244 1.00 51.40  ? 162 ARG   A N     1 
ATOM   1440 C CA    . ARG   C 2 150 ? 204.338 231.452 242.332 1.00 49.82  ? 162 ARG   A CA    1 
ATOM   1441 C C     . ARG   C 2 150 ? 204.387 232.136 240.972 1.00 47.77  ? 162 ARG   A C     1 
ATOM   1442 O O     . ARG   C 2 150 ? 203.803 233.214 240.819 1.00 48.77  ? 162 ARG   A O     1 
ATOM   1443 C CB    . ARG   C 2 150 ? 205.396 232.069 243.251 1.00 52.83  ? 162 ARG   A CB    1 
ATOM   1444 C CG    . ARG   C 2 150 ? 205.415 231.494 244.656 1.00 53.05  ? 162 ARG   A CG    1 
ATOM   1445 C CD    . ARG   C 2 150 ? 205.742 232.558 245.687 1.00 57.70  ? 162 ARG   A CD    1 
ATOM   1446 N NE    . ARG   C 2 150 ? 204.545 233.249 246.147 1.00 81.04  ? 162 ARG   A NE    1 
ATOM   1447 C CZ    . ARG   C 2 150 ? 204.480 233.989 247.246 1.00 84.79  ? 162 ARG   A CZ    1 
ATOM   1448 N NH1   . ARG   C 2 150 ? 205.534 234.161 248.025 1.00 88.61  ? 162 ARG   A NH1   1 
ATOM   1449 N NH2   . ARG   C 2 150 ? 203.329 234.572 247.570 1.00 68.04  ? 162 ARG   A NH2   1 
ATOM   1450 N N     . MET   C 2 151 ? 205.060 231.546 239.985 1.00 45.05  ? 163 MET   A N     1 
ATOM   1451 C CA    . MET   C 2 151 ? 205.147 232.155 238.658 1.00 45.21  ? 163 MET   A CA    1 
ATOM   1452 C C     . MET   C 2 151 ? 204.000 231.672 237.767 1.00 45.99  ? 163 MET   A C     1 
ATOM   1453 O O     . MET   C 2 151 ? 204.194 231.110 236.691 1.00 44.73  ? 163 MET   A O     1 
ATOM   1454 C CB    . MET   C 2 151 ? 206.500 231.873 238.015 1.00 45.63  ? 163 MET   A CB    1 
ATOM   1455 C CG    . MET   C 2 151 ? 207.022 230.460 238.171 1.00 48.28  ? 163 MET   A CG    1 
ATOM   1456 S SD    . MET   C 2 151 ? 208.705 230.293 237.540 1.00 55.14  ? 163 MET   A SD    1 
ATOM   1457 C CE    . MET   C 2 151 ? 209.637 230.057 239.043 1.00 43.59  ? 163 MET   A CE    1 
ATOM   1458 N N     . CYS   C 2 152 ? 202.781 231.912 238.241 1.00 47.81  ? 164 CYS   A N     1 
ATOM   1459 C CA    . CYS   C 2 152 ? 201.593 231.626 237.453 1.00 45.24  ? 164 CYS   A CA    1 
ATOM   1460 C C     . CYS   C 2 152 ? 201.290 232.715 236.436 1.00 45.48  ? 164 CYS   A C     1 
ATOM   1461 O O     . CYS   C 2 152 ? 200.498 232.482 235.518 1.00 47.33  ? 164 CYS   A O     1 
ATOM   1462 C CB    . CYS   C 2 152 ? 200.382 231.430 238.373 1.00 43.10  ? 164 CYS   A CB    1 
ATOM   1463 S SG    . CYS   C 2 152 ? 199.617 232.960 238.937 1.00 67.94  ? 164 CYS   A SG    1 
ATOM   1464 N N     . SER   C 2 153 ? 201.911 233.886 236.568 1.00 43.86  ? 165 SER   A N     1 
ATOM   1465 C CA    . SER   C 2 153 ? 201.713 234.961 235.607 1.00 43.88  ? 165 SER   A CA    1 
ATOM   1466 C C     . SER   C 2 153 ? 202.407 234.698 234.278 1.00 44.72  ? 165 SER   A C     1 
ATOM   1467 O O     . SER   C 2 153 ? 202.061 235.336 233.279 1.00 46.79  ? 165 SER   A O     1 
ATOM   1468 C CB    . SER   C 2 153 ? 202.211 236.282 236.194 1.00 45.76  ? 165 SER   A CB    1 
ATOM   1469 O OG    . SER   C 2 153 ? 203.602 236.430 235.989 1.00 51.56  ? 165 SER   A OG    1 
ATOM   1470 N N     . LEU   C 2 154 ? 203.369 233.781 234.243 1.00 43.72  ? 166 LEU   A N     1 
ATOM   1471 C CA    . LEU   C 2 154 ? 204.076 233.438 233.017 1.00 42.96  ? 166 LEU   A CA    1 
ATOM   1472 C C     . LEU   C 2 154 ? 203.450 232.259 232.286 1.00 45.37  ? 166 LEU   A C     1 
ATOM   1473 O O     . LEU   C 2 154 ? 204.006 231.804 231.282 1.00 48.14  ? 166 LEU   A O     1 
ATOM   1474 C CB    . LEU   C 2 154 ? 205.544 233.135 233.320 1.00 41.00  ? 166 LEU   A CB    1 
ATOM   1475 C CG    . LEU   C 2 154 ? 206.183 233.904 234.473 1.00 38.84  ? 166 LEU   A CG    1 
ATOM   1476 C CD1   . LEU   C 2 154 ? 207.543 233.322 234.801 1.00 38.59  ? 166 LEU   A CD1   1 
ATOM   1477 C CD2   . LEU   C 2 154 ? 206.297 235.378 234.137 1.00 42.62  ? 166 LEU   A CD2   1 
ATOM   1478 N N     . MET   C 2 155 ? 202.309 231.762 232.758 1.00 44.18  ? 167 MET   A N     1 
ATOM   1479 C CA    . MET   C 2 155 ? 201.659 230.591 232.188 1.00 43.46  ? 167 MET   A CA    1 
ATOM   1480 C C     . MET   C 2 155 ? 200.658 230.943 231.094 1.00 46.61  ? 167 MET   A C     1 
ATOM   1481 O O     . MET   C 2 155 ? 199.691 230.201 230.892 1.00 51.75  ? 167 MET   A O     1 
ATOM   1482 C CB    . MET   C 2 155 ? 200.969 229.787 233.288 1.00 46.25  ? 167 MET   A CB    1 
ATOM   1483 C CG    . MET   C 2 155 ? 201.919 228.929 234.089 1.00 49.32  ? 167 MET   A CG    1 
ATOM   1484 S SD    . MET   C 2 155 ? 203.070 228.059 233.016 1.00 57.97  ? 167 MET   A SD    1 
ATOM   1485 C CE    . MET   C 2 155 ? 204.586 228.262 233.931 1.00 48.77  ? 167 MET   A CE    1 
ATOM   1486 N N     . GLN   C 2 156 ? 200.860 232.057 230.398 1.00 46.46  ? 168 GLN   A N     1 
ATOM   1487 C CA    . GLN   C 2 156 ? 199.963 232.443 229.318 1.00 45.57  ? 168 GLN   A CA    1 
ATOM   1488 C C     . GLN   C 2 156 ? 200.040 231.437 228.177 1.00 44.59  ? 168 GLN   A C     1 
ATOM   1489 O O     . GLN   C 2 156 ? 201.128 231.087 227.715 1.00 46.97  ? 168 GLN   A O     1 
ATOM   1490 C CB    . GLN   C 2 156 ? 200.324 233.844 228.822 1.00 43.79  ? 168 GLN   A CB    1 
ATOM   1491 C CG    . GLN   C 2 156 ? 199.668 234.250 227.514 1.00 45.80  ? 168 GLN   A CG    1 
ATOM   1492 C CD    . GLN   C 2 156 ? 198.269 234.800 227.692 1.00 51.65  ? 168 GLN   A CD    1 
ATOM   1493 O OE1   . GLN   C 2 156 ? 197.475 234.277 228.471 1.00 57.96  ? 168 GLN   A OE1   1 
ATOM   1494 N NE2   . GLN   C 2 156 ? 197.960 235.863 226.961 1.00 50.14  ? 168 GLN   A NE2   1 
ATOM   1495 N N     . GLY   C 2 157 ? 198.880 230.972 227.724 1.00 43.78  ? 169 GLY   A N     1 
ATOM   1496 C CA    . GLY   C 2 157 ? 198.834 230.012 226.631 1.00 46.01  ? 169 GLY   A CA    1 
ATOM   1497 C C     . GLY   C 2 157 ? 199.424 228.661 226.969 1.00 47.54  ? 169 GLY   A C     1 
ATOM   1498 O O     . GLY   C 2 157 ? 200.055 228.030 226.113 1.00 49.31  ? 169 GLY   A O     1 
ATOM   1499 N N     . SER   C 2 158 ? 199.230 228.196 228.203 1.00 48.87  ? 170 SER   A N     1 
ATOM   1500 C CA    . SER   C 2 158 ? 199.782 226.911 228.614 1.00 47.41  ? 170 SER   A CA    1 
ATOM   1501 C C     . SER   C 2 158 ? 198.983 225.734 228.071 1.00 46.32  ? 170 SER   A C     1 
ATOM   1502 O O     . SER   C 2 158 ? 199.565 224.685 227.776 1.00 49.18  ? 170 SER   A O     1 
ATOM   1503 C CB    . SER   C 2 158 ? 199.850 226.835 230.138 1.00 47.01  ? 170 SER   A CB    1 
ATOM   1504 O OG    . SER   C 2 158 ? 198.665 227.347 230.719 1.00 56.59  ? 170 SER   A OG    1 
ATOM   1505 N N     . THR   C 2 159 ? 197.670 225.881 227.928 1.00 45.21  ? 171 THR   A N     1 
ATOM   1506 C CA    . THR   C 2 159 ? 196.818 224.787 227.484 1.00 44.68  ? 171 THR   A CA    1 
ATOM   1507 C C     . THR   C 2 159 ? 196.775 224.639 225.971 1.00 46.15  ? 171 THR   A C     1 
ATOM   1508 O O     . THR   C 2 159 ? 196.032 223.789 225.469 1.00 49.67  ? 171 THR   A O     1 
ATOM   1509 C CB    . THR   C 2 159 ? 195.393 224.973 228.014 1.00 47.74  ? 171 THR   A CB    1 
ATOM   1510 O OG1   . THR   C 2 159 ? 194.935 226.293 227.700 1.00 51.47  ? 171 THR   A OG1   1 
ATOM   1511 C CG2   . THR   C 2 159 ? 195.352 224.772 229.517 1.00 48.40  ? 171 THR   A CG2   1 
ATOM   1512 N N     . LEU   C 2 160 ? 197.536 225.436 225.239 1.00 44.92  ? 172 LEU   A N     1 
ATOM   1513 C CA    . LEU   C 2 160 ? 197.520 225.347 223.785 1.00 44.98  ? 172 LEU   A CA    1 
ATOM   1514 C C     . LEU   C 2 160 ? 198.151 224.037 223.329 1.00 46.43  ? 172 LEU   A C     1 
ATOM   1515 O O     . LEU   C 2 160 ? 199.244 223.687 223.789 1.00 49.72  ? 172 LEU   A O     1 
ATOM   1516 C CB    . LEU   C 2 160 ? 198.263 226.525 223.167 1.00 42.60  ? 172 LEU   A CB    1 
ATOM   1517 C CG    . LEU   C 2 160 ? 197.418 227.758 222.856 1.00 41.39  ? 172 LEU   A CG    1 
ATOM   1518 C CD1   . LEU   C 2 160 ? 198.285 228.836 222.256 1.00 41.25  ? 172 LEU   A CD1   1 
ATOM   1519 C CD2   . LEU   C 2 160 ? 196.283 227.404 221.917 1.00 45.51  ? 172 LEU   A CD2   1 
ATOM   1520 N N     . PRO   C 2 161 ? 197.501 223.287 222.445 1.00 44.24  ? 173 PRO   A N     1 
ATOM   1521 C CA    . PRO   C 2 161 ? 198.135 222.094 221.883 1.00 44.14  ? 173 PRO   A CA    1 
ATOM   1522 C C     . PRO   C 2 161 ? 199.273 222.459 220.942 1.00 43.98  ? 173 PRO   A C     1 
ATOM   1523 O O     . PRO   C 2 161 ? 199.362 223.572 220.423 1.00 44.98  ? 173 PRO   A O     1 
ATOM   1524 C CB    . PRO   C 2 161 ? 196.994 221.400 221.134 1.00 43.81  ? 173 PRO   A CB    1 
ATOM   1525 C CG    . PRO   C 2 161 ? 196.025 222.482 220.840 1.00 43.27  ? 173 PRO   A CG    1 
ATOM   1526 C CD    . PRO   C 2 161 ? 196.120 223.461 221.968 1.00 40.54  ? 173 PRO   A CD    1 
ATOM   1527 N N     . ARG   C 2 162 ? 200.160 221.485 220.734 1.00 45.14  ? 174 ARG   A N     1 
ATOM   1528 C CA    . ARG   C 2 162 ? 201.334 221.694 219.896 1.00 49.51  ? 174 ARG   A CA    1 
ATOM   1529 C C     . ARG   C 2 162 ? 200.974 222.015 218.451 1.00 47.12  ? 174 ARG   A C     1 
ATOM   1530 O O     . ARG   C 2 162 ? 201.732 222.722 217.777 1.00 47.07  ? 174 ARG   A O     1 
ATOM   1531 C CB    . ARG   C 2 162 ? 202.232 220.457 219.962 1.00 57.10  ? 174 ARG   A CB    1 
ATOM   1532 C CG    . ARG   C 2 162 ? 203.426 220.475 219.020 1.00 59.13  ? 174 ARG   A CG    1 
ATOM   1533 C CD    . ARG   C 2 162 ? 204.500 221.480 219.441 1.00 59.99  ? 174 ARG   A CD    1 
ATOM   1534 N NE    . ARG   C 2 162 ? 204.603 221.708 220.881 1.00 66.73  ? 174 ARG   A NE    1 
ATOM   1535 C CZ    . ARG   C 2 162 ? 204.900 220.783 221.785 1.00 69.61  ? 174 ARG   A CZ    1 
ATOM   1536 N NH1   . ARG   C 2 162 ? 205.178 219.537 221.438 1.00 68.40  ? 174 ARG   A NH1   1 
ATOM   1537 N NH2   . ARG   C 2 162 ? 204.930 221.121 223.071 1.00 65.29  ? 174 ARG   A NH2   1 
ATOM   1538 N N     . ARG   C 2 163 ? 199.824 221.545 217.967 1.00 46.31  ? 175 ARG   A N     1 
ATOM   1539 C CA    . ARG   C 2 163 ? 199.449 221.738 216.572 1.00 45.27  ? 175 ARG   A CA    1 
ATOM   1540 C C     . ARG   C 2 163 ? 199.178 223.195 216.219 1.00 45.65  ? 175 ARG   A C     1 
ATOM   1541 O O     . ARG   C 2 163 ? 199.055 223.510 215.031 1.00 46.09  ? 175 ARG   A O     1 
ATOM   1542 C CB    . ARG   C 2 163 ? 198.225 220.883 216.248 1.00 46.15  ? 175 ARG   A CB    1 
ATOM   1543 C CG    . ARG   C 2 163 ? 197.023 221.202 217.102 1.00 49.16  ? 175 ARG   A CG    1 
ATOM   1544 C CD    . ARG   C 2 163 ? 195.752 220.640 216.510 1.00 46.54  ? 175 ARG   A CD    1 
ATOM   1545 N NE    . ARG   C 2 163 ? 194.837 220.199 217.554 1.00 47.21  ? 175 ARG   A NE    1 
ATOM   1546 C CZ    . ARG   C 2 163 ? 193.524 220.110 217.407 1.00 53.91  ? 175 ARG   A CZ    1 
ATOM   1547 N NH1   . ARG   C 2 163 ? 192.936 220.416 216.264 1.00 55.40  ? 175 ARG   A NH1   1 
ATOM   1548 N NH2   . ARG   C 2 163 ? 192.783 219.705 218.434 1.00 57.71  ? 175 ARG   A NH2   1 
ATOM   1549 N N     . SER   C 2 164 ? 199.072 224.082 217.205 1.00 47.53  ? 176 SER   A N     1 
ATOM   1550 C CA    . SER   C 2 164 ? 198.978 225.507 216.921 1.00 46.52  ? 176 SER   A CA    1 
ATOM   1551 C C     . SER   C 2 164 ? 200.246 225.995 216.233 1.00 48.07  ? 176 SER   A C     1 
ATOM   1552 O O     . SER   C 2 164 ? 201.361 225.630 216.617 1.00 47.99  ? 176 SER   A O     1 
ATOM   1553 C CB    . SER   C 2 164 ? 198.747 226.292 218.209 1.00 44.42  ? 176 SER   A CB    1 
ATOM   1554 O OG    . SER   C 2 164 ? 199.861 226.177 219.075 1.00 49.71  ? 176 SER   A OG    1 
ATOM   1555 N N     . GLY   C 2 165 ? 200.073 226.832 215.216 1.00 47.72  ? 177 GLY   A N     1 
ATOM   1556 C CA    . GLY   C 2 165 ? 201.191 227.291 214.417 1.00 47.46  ? 177 GLY   A CA    1 
ATOM   1557 C C     . GLY   C 2 165 ? 202.012 228.382 215.068 1.00 45.61  ? 177 GLY   A C     1 
ATOM   1558 O O     . GLY   C 2 165 ? 202.248 228.357 216.280 1.00 44.91  ? 177 GLY   A O     1 
ATOM   1559 N N     . ALA   C 2 166 ? 202.468 229.344 214.262 1.00 46.65  ? 178 ALA   A N     1 
ATOM   1560 C CA    . ALA   C 2 166 ? 203.256 230.448 214.796 1.00 49.03  ? 178 ALA   A CA    1 
ATOM   1561 C C     . ALA   C 2 166 ? 202.439 231.322 215.737 1.00 51.67  ? 178 ALA   A C     1 
ATOM   1562 O O     . ALA   C 2 166 ? 203.000 231.947 216.643 1.00 56.39  ? 178 ALA   A O     1 
ATOM   1563 C CB    . ALA   C 2 166 ? 203.825 231.286 213.652 1.00 51.73  ? 178 ALA   A CB    1 
ATOM   1564 N N     . ALA   C 2 167 ? 201.121 231.387 215.536 1.00 43.75  ? 179 ALA   A N     1 
ATOM   1565 C CA    . ALA   C 2 167 ? 200.276 232.170 216.432 1.00 46.47  ? 179 ALA   A CA    1 
ATOM   1566 C C     . ALA   C 2 167 ? 200.303 231.606 217.847 1.00 48.94  ? 179 ALA   A C     1 
ATOM   1567 O O     . ALA   C 2 167 ? 200.384 232.361 218.826 1.00 52.72  ? 179 ALA   A O     1 
ATOM   1568 C CB    . ALA   C 2 167 ? 198.846 232.217 215.899 1.00 46.73  ? 179 ALA   A CB    1 
ATOM   1569 N N     . GLY   C 2 168 ? 200.239 230.279 217.974 1.00 45.38  ? 180 GLY   A N     1 
ATOM   1570 C CA    . GLY   C 2 168 ? 200.307 229.670 219.291 1.00 44.37  ? 180 GLY   A CA    1 
ATOM   1571 C C     . GLY   C 2 168 ? 201.627 229.932 219.987 1.00 43.68  ? 180 GLY   A C     1 
ATOM   1572 O O     . GLY   C 2 168 ? 201.659 230.230 221.184 1.00 45.35  ? 180 GLY   A O     1 
ATOM   1573 N N     . ALA   C 2 169 ? 202.733 229.834 219.248 1.00 43.35  ? 181 ALA   A N     1 
ATOM   1574 C CA    . ALA   C 2 169 ? 204.038 230.144 219.817 1.00 44.23  ? 181 ALA   A CA    1 
ATOM   1575 C C     . ALA   C 2 169 ? 204.163 231.608 220.205 1.00 44.59  ? 181 ALA   A C     1 
ATOM   1576 O O     . ALA   C 2 169 ? 204.810 231.917 221.210 1.00 44.22  ? 181 ALA   A O     1 
ATOM   1577 C CB    . ALA   C 2 169 ? 205.145 229.781 218.830 1.00 44.51  ? 181 ALA   A CB    1 
ATOM   1578 N N     . ALA   C 2 170 ? 203.564 232.511 219.431 1.00 42.47  ? 182 ALA   A N     1 
ATOM   1579 C CA    . ALA   C 2 170 ? 203.638 233.929 219.756 1.00 43.35  ? 182 ALA   A CA    1 
ATOM   1580 C C     . ALA   C 2 170 ? 202.827 234.264 220.998 1.00 45.70  ? 182 ALA   A C     1 
ATOM   1581 O O     . ALA   C 2 170 ? 203.257 235.077 221.821 1.00 48.50  ? 182 ALA   A O     1 
ATOM   1582 C CB    . ALA   C 2 170 ? 203.157 234.764 218.572 1.00 39.76  ? 182 ALA   A CB    1 
ATOM   1583 N N     . VAL   C 2 171 ? 201.653 233.650 221.154 1.00 44.47  ? 183 VAL   A N     1 
ATOM   1584 C CA    . VAL   C 2 171 ? 200.791 234.017 222.270 1.00 44.59  ? 183 VAL   A CA    1 
ATOM   1585 C C     . VAL   C 2 171 ? 201.181 233.310 223.564 1.00 45.25  ? 183 VAL   A C     1 
ATOM   1586 O O     . VAL   C 2 171 ? 200.902 233.830 224.650 1.00 46.09  ? 183 VAL   A O     1 
ATOM   1587 C CB    . VAL   C 2 171 ? 199.319 233.743 221.915 1.00 41.65  ? 183 VAL   A CB    1 
ATOM   1588 C CG1   . VAL   C 2 171 ? 199.079 232.260 221.738 1.00 46.06  ? 183 VAL   A CG1   1 
ATOM   1589 C CG2   . VAL   C 2 171 ? 198.381 234.337 222.957 1.00 39.99  ? 183 VAL   A CG2   1 
ATOM   1590 N N     . LYS   C 2 172 ? 201.838 232.157 223.492 1.00 45.00  ? 184 LYS   A N     1 
ATOM   1591 C CA    . LYS   C 2 172 ? 202.165 231.426 224.708 1.00 45.09  ? 184 LYS   A CA    1 
ATOM   1592 C C     . LYS   C 2 172 ? 203.319 232.094 225.447 1.00 44.83  ? 184 LYS   A C     1 
ATOM   1593 O O     . LYS   C 2 172 ? 204.230 232.658 224.837 1.00 46.44  ? 184 LYS   A O     1 
ATOM   1594 C CB    . LYS   C 2 172 ? 202.493 229.967 224.390 1.00 42.11  ? 184 LYS   A CB    1 
ATOM   1595 C CG    . LYS   C 2 172 ? 203.815 229.729 223.697 1.00 42.22  ? 184 LYS   A CG    1 
ATOM   1596 C CD    . LYS   C 2 172 ? 204.063 228.239 223.502 1.00 44.44  ? 184 LYS   A CD    1 
ATOM   1597 C CE    . LYS   C 2 172 ? 202.775 227.463 223.291 1.00 35.69  ? 184 LYS   A CE    1 
ATOM   1598 N NZ    . LYS   C 2 172 ? 203.047 226.057 222.897 1.00 31.42  ? 184 LYS   A NZ    1 
ATOM   1599 N N     . GLY   C 2 173 ? 203.267 232.034 226.776 1.00 45.80  ? 185 GLY   A N     1 
ATOM   1600 C CA    . GLY   C 2 173 ? 204.173 232.790 227.610 1.00 44.10  ? 185 GLY   A CA    1 
ATOM   1601 C C     . GLY   C 2 173 ? 205.513 232.116 227.815 1.00 47.16  ? 185 GLY   A C     1 
ATOM   1602 O O     . GLY   C 2 173 ? 205.777 231.009 227.348 1.00 50.70  ? 185 GLY   A O     1 
ATOM   1603 N N     . VAL   C 2 174 ? 206.381 232.821 228.540 1.00 45.05  ? 186 VAL   A N     1 
ATOM   1604 C CA    . VAL   C 2 174 ? 207.724 232.317 228.807 1.00 44.96  ? 186 VAL   A CA    1 
ATOM   1605 C C     . VAL   C 2 174 ? 207.668 231.108 229.732 1.00 44.41  ? 186 VAL   A C     1 
ATOM   1606 O O     . VAL   C 2 174 ? 208.436 230.151 229.577 1.00 44.30  ? 186 VAL   A O     1 
ATOM   1607 C CB    . VAL   C 2 174 ? 208.602 233.439 229.390 1.00 40.98  ? 186 VAL   A CB    1 
ATOM   1608 C CG1   . VAL   C 2 174 ? 209.998 232.929 229.691 1.00 40.72  ? 186 VAL   A CG1   1 
ATOM   1609 C CG2   . VAL   C 2 174 ? 208.650 234.618 228.437 1.00 44.87  ? 186 VAL   A CG2   1 
ATOM   1610 N N     . GLY   C 2 175 ? 206.759 231.134 230.707 1.00 43.55  ? 187 GLY   A N     1 
ATOM   1611 C CA    . GLY   C 2 175 ? 206.650 230.022 231.634 1.00 41.97  ? 187 GLY   A CA    1 
ATOM   1612 C C     . GLY   C 2 175 ? 206.282 228.721 230.949 1.00 43.07  ? 187 GLY   A C     1 
ATOM   1613 O O     . GLY   C 2 175 ? 206.796 227.659 231.301 1.00 46.13  ? 187 GLY   A O     1 
ATOM   1614 N N     . THR   C 2 176 ? 205.383 228.783 229.965 1.00 41.62  ? 188 THR   A N     1 
ATOM   1615 C CA    . THR   C 2 176 ? 205.004 227.574 229.240 1.00 42.68  ? 188 THR   A CA    1 
ATOM   1616 C C     . THR   C 2 176 ? 206.167 227.031 228.421 1.00 44.19  ? 188 THR   A C     1 
ATOM   1617 O O     . THR   C 2 176 ? 206.348 225.812 228.321 1.00 49.54  ? 188 THR   A O     1 
ATOM   1618 C CB    . THR   C 2 176 ? 203.802 227.854 228.341 1.00 44.32  ? 188 THR   A CB    1 
ATOM   1619 O OG1   . THR   C 2 176 ? 204.251 228.386 227.091 1.00 48.30  ? 188 THR   A OG1   1 
ATOM   1620 C CG2   . THR   C 2 176 ? 202.887 228.855 229.005 1.00 43.96  ? 188 THR   A CG2   1 
ATOM   1621 N N     . MET   C 2 177 ? 206.956 227.918 227.814 1.00 42.04  ? 189 MET   A N     1 
ATOM   1622 C CA    . MET   C 2 177 ? 208.144 227.474 227.095 1.00 43.07  ? 189 MET   A CA    1 
ATOM   1623 C C     . MET   C 2 177 ? 209.134 226.803 228.035 1.00 43.25  ? 189 MET   A C     1 
ATOM   1624 O O     . MET   C 2 177 ? 209.726 225.768 227.701 1.00 43.21  ? 189 MET   A O     1 
ATOM   1625 C CB    . MET   C 2 177 ? 208.800 228.648 226.381 1.00 45.57  ? 189 MET   A CB    1 
ATOM   1626 C CG    . MET   C 2 177 ? 207.853 229.487 225.570 1.00 44.34  ? 189 MET   A CG    1 
ATOM   1627 S SD    . MET   C 2 177 ? 207.459 228.541 224.105 1.00 52.13  ? 189 MET   A SD    1 
ATOM   1628 C CE    . MET   C 2 177 ? 209.093 228.427 223.413 1.00 49.25  ? 189 MET   A CE    1 
ATOM   1629 N N     . VAL   C 2 178 ? 209.334 227.390 229.216 1.00 42.88  ? 190 VAL   A N     1 
ATOM   1630 C CA    . VAL   C 2 178 ? 210.218 226.776 230.200 1.00 41.41  ? 190 VAL   A CA    1 
ATOM   1631 C C     . VAL   C 2 178 ? 209.667 225.423 230.632 1.00 41.38  ? 190 VAL   A C     1 
ATOM   1632 O O     . VAL   C 2 178 ? 210.422 224.468 230.830 1.00 40.14  ? 190 VAL   A O     1 
ATOM   1633 C CB    . VAL   C 2 178 ? 210.428 227.718 231.399 1.00 42.96  ? 190 VAL   A CB    1 
ATOM   1634 C CG1   . VAL   C 2 178 ? 211.284 227.052 232.458 1.00 44.51  ? 190 VAL   A CG1   1 
ATOM   1635 C CG2   . VAL   C 2 178 ? 211.083 229.007 230.944 1.00 40.45  ? 190 VAL   A CG2   1 
ATOM   1636 N N     . MET   C 2 179 ? 208.342 225.315 230.763 1.00 44.68  ? 191 MET   A N     1 
ATOM   1637 C CA    . MET   C 2 179 ? 207.730 224.037 231.116 1.00 44.74  ? 191 MET   A CA    1 
ATOM   1638 C C     . MET   C 2 179 ? 207.986 222.983 230.049 1.00 44.48  ? 191 MET   A C     1 
ATOM   1639 O O     . MET   C 2 179 ? 208.337 221.843 230.368 1.00 45.72  ? 191 MET   A O     1 
ATOM   1640 C CB    . MET   C 2 179 ? 206.227 224.214 231.334 1.00 46.58  ? 191 MET   A CB    1 
ATOM   1641 C CG    . MET   C 2 179 ? 205.803 224.260 232.790 1.00 48.67  ? 191 MET   A CG    1 
ATOM   1642 S SD    . MET   C 2 179 ? 204.018 224.146 233.024 1.00 56.60  ? 191 MET   A SD    1 
ATOM   1643 C CE    . MET   C 2 179 ? 203.515 223.347 231.505 1.00 52.27  ? 191 MET   A CE    1 
ATOM   1644 N N     . GLU   C 2 180 ? 207.804 223.340 228.777 1.00 44.09  ? 192 GLU   A N     1 
ATOM   1645 C CA    . GLU   C 2 180 ? 208.049 222.385 227.699 1.00 44.25  ? 192 GLU   A CA    1 
ATOM   1646 C C     . GLU   C 2 180 ? 209.510 221.953 227.669 1.00 44.52  ? 192 GLU   A C     1 
ATOM   1647 O O     . GLU   C 2 180 ? 209.817 220.758 227.549 1.00 45.54  ? 192 GLU   A O     1 
ATOM   1648 C CB    . GLU   C 2 180 ? 207.647 222.992 226.355 1.00 47.03  ? 192 GLU   A CB    1 
ATOM   1649 C CG    . GLU   C 2 180 ? 206.287 222.552 225.842 1.00 51.48  ? 192 GLU   A CG    1 
ATOM   1650 C CD    . GLU   C 2 180 ? 205.155 223.401 226.378 1.00 53.80  ? 192 GLU   A CD    1 
ATOM   1651 O OE1   . GLU   C 2 180 ? 205.107 224.603 226.046 1.00 54.74  ? 192 GLU   A OE1   1 
ATOM   1652 O OE2   . GLU   C 2 180 ? 204.313 222.871 227.129 1.00 56.58  ? 192 GLU   A OE2   1 
ATOM   1653 N N     . LEU   C 2 181 ? 210.426 222.917 227.791 1.00 45.12  ? 193 LEU   A N     1 
ATOM   1654 C CA    . LEU   C 2 181 ? 211.845 222.586 227.789 1.00 44.75  ? 193 LEU   A CA    1 
ATOM   1655 C C     . LEU   C 2 181 ? 212.203 221.702 228.973 1.00 47.17  ? 193 LEU   A C     1 
ATOM   1656 O O     . LEU   C 2 181 ? 212.977 220.752 228.832 1.00 49.29  ? 193 LEU   A O     1 
ATOM   1657 C CB    . LEU   C 2 181 ? 212.687 223.860 227.802 1.00 45.60  ? 193 LEU   A CB    1 
ATOM   1658 C CG    . LEU   C 2 181 ? 212.747 224.666 226.507 1.00 46.53  ? 193 LEU   A CG    1 
ATOM   1659 C CD1   . LEU   C 2 181 ? 213.653 225.865 226.682 1.00 45.79  ? 193 LEU   A CD1   1 
ATOM   1660 C CD2   . LEU   C 2 181 ? 213.231 223.797 225.371 1.00 47.76  ? 193 LEU   A CD2   1 
ATOM   1661 N N     . ILE   C 2 182 ? 211.639 221.990 230.147 1.00 46.03  ? 194 ILE   A N     1 
ATOM   1662 C CA    . ILE   C 2 182 ? 211.942 221.207 231.337 1.00 45.33  ? 194 ILE   A CA    1 
ATOM   1663 C C     . ILE   C 2 182 ? 211.375 219.801 231.211 1.00 46.50  ? 194 ILE   A C     1 
ATOM   1664 O O     . ILE   C 2 182 ? 211.990 218.832 231.662 1.00 47.18  ? 194 ILE   A O     1 
ATOM   1665 C CB    . ILE   C 2 182 ? 211.422 221.931 232.592 1.00 50.10  ? 194 ILE   A CB    1 
ATOM   1666 C CG1   . ILE   C 2 182 ? 212.357 223.079 232.965 1.00 46.25  ? 194 ILE   A CG1   1 
ATOM   1667 C CG2   . ILE   C 2 182 ? 211.285 220.974 233.763 1.00 52.81  ? 194 ILE   A CG2   1 
ATOM   1668 C CD1   . ILE   C 2 182 ? 211.863 223.903 234.119 1.00 44.66  ? 194 ILE   A CD1   1 
ATOM   1669 N N     . ARG   C 2 183 ? 210.195 219.662 230.602 1.00 47.38  ? 195 ARG   A N     1 
ATOM   1670 C CA    . ARG   C 2 183 ? 209.658 218.328 230.351 1.00 46.61  ? 195 ARG   A CA    1 
ATOM   1671 C C     . ARG   C 2 183 ? 210.578 217.538 229.433 1.00 47.48  ? 195 ARG   A C     1 
ATOM   1672 O O     . ARG   C 2 183 ? 210.819 216.347 229.657 1.00 50.49  ? 195 ARG   A O     1 
ATOM   1673 C CB    . ARG   C 2 183 ? 208.256 218.420 229.752 1.00 45.39  ? 195 ARG   A CB    1 
ATOM   1674 C CG    . ARG   C 2 183 ? 207.171 218.758 230.756 1.00 50.54  ? 195 ARG   A CG    1 
ATOM   1675 C CD    . ARG   C 2 183 ? 206.115 219.657 230.149 1.00 52.78  ? 195 ARG   A CD    1 
ATOM   1676 N NE    . ARG   C 2 183 ? 204.901 219.679 230.954 1.00 58.15  ? 195 ARG   A NE    1 
ATOM   1677 C CZ    . ARG   C 2 183 ? 203.893 218.830 230.807 1.00 66.87  ? 195 ARG   A CZ    1 
ATOM   1678 N NH1   . ARG   C 2 183 ? 203.921 217.878 229.889 1.00 73.46  ? 195 ARG   A NH1   1 
ATOM   1679 N NH2   . ARG   C 2 183 ? 202.832 218.939 231.601 1.00 72.31  ? 195 ARG   A NH2   1 
ATOM   1680 N N     . MET   C 2 184 ? 211.108 218.189 228.396 1.00 48.00  ? 196 MET   A N     1 
ATOM   1681 C CA    . MET   C 2 184 ? 212.070 217.520 227.523 1.00 47.13  ? 196 MET   A CA    1 
ATOM   1682 C C     . MET   C 2 184 ? 213.335 217.135 228.288 1.00 49.60  ? 196 MET   A C     1 
ATOM   1683 O O     . MET   C 2 184 ? 213.888 216.045 228.091 1.00 51.34  ? 196 MET   A O     1 
ATOM   1684 C CB    . MET   C 2 184 ? 212.401 218.422 226.335 1.00 45.45  ? 196 MET   A CB    1 
ATOM   1685 C CG    . MET   C 2 184 ? 213.016 217.704 225.156 1.00 52.21  ? 196 MET   A CG    1 
ATOM   1686 S SD    . MET   C 2 184 ? 212.627 218.498 223.586 1.00 59.47  ? 196 MET   A SD    1 
ATOM   1687 C CE    . MET   C 2 184 ? 210.841 218.398 223.592 1.00 34.68  ? 196 MET   A CE    1 
ATOM   1688 N N     . ILE   C 2 185 ? 213.803 218.023 229.171 1.00 48.67  ? 197 ILE   A N     1 
ATOM   1689 C CA    . ILE   C 2 185 ? 214.988 217.745 229.983 1.00 46.75  ? 197 ILE   A CA    1 
ATOM   1690 C C     . ILE   C 2 185 ? 214.753 216.527 230.868 1.00 49.29  ? 197 ILE   A C     1 
ATOM   1691 O O     . ILE   C 2 185 ? 215.599 215.632 230.962 1.00 51.44  ? 197 ILE   A O     1 
ATOM   1692 C CB    . ILE   C 2 185 ? 215.355 218.977 230.828 1.00 51.45  ? 197 ILE   A CB    1 
ATOM   1693 C CG1   . ILE   C 2 185 ? 215.741 220.160 229.940 1.00 46.83  ? 197 ILE   A CG1   1 
ATOM   1694 C CG2   . ILE   C 2 185 ? 216.469 218.638 231.810 1.00 52.94  ? 197 ILE   A CG2   1 
ATOM   1695 C CD1   . ILE   C 2 185 ? 217.202 220.290 229.684 1.00 46.26  ? 197 ILE   A CD1   1 
ATOM   1696 N N     . LYS   C 2 186 ? 213.602 216.486 231.541 1.00 49.64  ? 198 LYS   A N     1 
ATOM   1697 C CA    . LYS   C 2 186 ? 213.275 215.358 232.407 1.00 50.49  ? 198 LYS   A CA    1 
ATOM   1698 C C     . LYS   C 2 186 ? 213.155 214.070 231.608 1.00 54.11  ? 198 LYS   A C     1 
ATOM   1699 O O     . LYS   C 2 186 ? 213.601 213.008 232.060 1.00 55.99  ? 198 LYS   A O     1 
ATOM   1700 C CB    . LYS   C 2 186 ? 211.975 215.628 233.166 1.00 50.22  ? 198 LYS   A CB    1 
ATOM   1701 C CG    . LYS   C 2 186 ? 211.985 216.867 234.036 1.00 46.74  ? 198 LYS   A CG    1 
ATOM   1702 C CD    . LYS   C 2 186 ? 213.184 216.905 234.953 1.00 49.47  ? 198 LYS   A CD    1 
ATOM   1703 C CE    . LYS   C 2 186 ? 212.918 217.828 236.121 1.00 50.15  ? 198 LYS   A CE    1 
ATOM   1704 N NZ    . LYS   C 2 186 ? 211.519 217.685 236.598 1.00 45.94  ? 198 LYS   A NZ    1 
ATOM   1705 N N     . ARG   C 2 187 ? 212.541 214.140 230.424 1.00 54.71  ? 199 ARG   A N     1 
ATOM   1706 C CA    . ARG   C 2 187 ? 212.413 212.954 229.588 1.00 54.13  ? 199 ARG   A CA    1 
ATOM   1707 C C     . ARG   C 2 187 ? 213.777 212.426 229.173 1.00 55.28  ? 199 ARG   A C     1 
ATOM   1708 O O     . ARG   C 2 187 ? 213.995 211.210 229.162 1.00 55.28  ? 199 ARG   A O     1 
ATOM   1709 C CB    . ARG   C 2 187 ? 211.563 213.272 228.359 1.00 56.57  ? 199 ARG   A CB    1 
ATOM   1710 C CG    . ARG   C 2 187 ? 211.286 212.076 227.470 1.00 63.91  ? 199 ARG   A CG    1 
ATOM   1711 C CD    . ARG   C 2 187 ? 210.314 211.104 228.131 1.00 67.56  ? 199 ARG   A CD    1 
ATOM   1712 N NE    . ARG   C 2 187 ? 209.087 211.716 228.641 1.00 68.82  ? 199 ARG   A NE    1 
ATOM   1713 C CZ    . ARG   C 2 187 ? 208.273 212.517 227.961 1.00 68.56  ? 199 ARG   A CZ    1 
ATOM   1714 N NH1   . ARG   C 2 187 ? 208.463 212.781 226.678 1.00 64.42  ? 199 ARG   A NH1   1 
ATOM   1715 N NH2   . ARG   C 2 187 ? 207.220 213.043 228.579 1.00 73.03  ? 199 ARG   A NH2   1 
ATOM   1716 N N     . GLY   C 2 188 ? 214.709 213.321 228.837 1.00 55.27  ? 200 GLY   A N     1 
ATOM   1717 C CA    . GLY   C 2 188 ? 216.061 212.893 228.528 1.00 53.70  ? 200 GLY   A CA    1 
ATOM   1718 C C     . GLY   C 2 188 ? 216.834 212.386 229.727 1.00 55.12  ? 200 GLY   A C     1 
ATOM   1719 O O     . GLY   C 2 188 ? 217.696 211.517 229.573 1.00 61.20  ? 200 GLY   A O     1 
ATOM   1720 N N     . ILE   C 2 189 ? 216.541 212.906 230.916 1.00 54.75  ? 201 ILE   A N     1 
ATOM   1721 C CA    . ILE   C 2 189 ? 217.208 212.433 232.124 1.00 52.78  ? 201 ILE   A CA    1 
ATOM   1722 C C     . ILE   C 2 189 ? 216.739 211.029 232.480 1.00 56.64  ? 201 ILE   A C     1 
ATOM   1723 O O     . ILE   C 2 189 ? 217.539 210.174 232.876 1.00 61.36  ? 201 ILE   A O     1 
ATOM   1724 C CB    . ILE   C 2 189 ? 216.974 213.422 233.282 1.00 52.25  ? 201 ILE   A CB    1 
ATOM   1725 C CG1   . ILE   C 2 189 ? 217.883 214.641 233.132 1.00 48.61  ? 201 ILE   A CG1   1 
ATOM   1726 C CG2   . ILE   C 2 189 ? 217.214 212.754 234.621 1.00 52.57  ? 201 ILE   A CG2   1 
ATOM   1727 C CD1   . ILE   C 2 189 ? 217.537 215.769 234.071 1.00 50.07  ? 201 ILE   A CD1   1 
ATOM   1728 N N     . ASN   C 2 190 ? 215.435 210.771 232.338 1.00 56.57  ? 202 ASN   A N     1 
ATOM   1729 C CA    . ASN   C 2 190 ? 214.897 209.450 232.645 1.00 58.41  ? 202 ASN   A CA    1 
ATOM   1730 C C     . ASN   C 2 190 ? 215.507 208.374 231.754 1.00 64.03  ? 202 ASN   A C     1 
ATOM   1731 O O     . ASN   C 2 190 ? 216.018 207.362 232.247 1.00 70.10  ? 202 ASN   A O     1 
ATOM   1732 C CB    . ASN   C 2 190 ? 213.375 209.459 232.498 1.00 58.97  ? 202 ASN   A CB    1 
ATOM   1733 C CG    . ASN   C 2 190 ? 212.695 210.306 233.545 1.00 63.48  ? 202 ASN   A CG    1 
ATOM   1734 O OD1   . ASN   C 2 190 ? 213.256 210.564 234.609 1.00 67.19  ? 202 ASN   A OD1   1 
ATOM   1735 N ND2   . ASN   C 2 190 ? 211.474 210.737 233.258 1.00 63.81  ? 202 ASN   A ND2   1 
ATOM   1736 N N     . ASP   C 2 191 ? 215.464 208.574 230.440 1.00 63.24  ? 203 ASP   A N     1 
ATOM   1737 C CA    . ASP   C 2 191 ? 215.951 207.588 229.481 1.00 64.80  ? 203 ASP   A CA    1 
ATOM   1738 C C     . ASP   C 2 191 ? 217.072 208.219 228.665 1.00 66.28  ? 203 ASP   A C     1 
ATOM   1739 O O     . ASP   C 2 191 ? 216.849 209.206 227.958 1.00 69.14  ? 203 ASP   A O     1 
ATOM   1740 C CB    . ASP   C 2 191 ? 214.820 207.098 228.579 1.00 67.84  ? 203 ASP   A CB    1 
ATOM   1741 C CG    . ASP   C 2 191 ? 215.323 206.566 227.257 1.00 77.98  ? 203 ASP   A CG    1 
ATOM   1742 O OD1   . ASP   C 2 191 ? 215.839 205.430 227.233 1.00 81.79  ? 203 ASP   A OD1   1 
ATOM   1743 O OD2   . ASP   C 2 191 ? 215.201 207.282 226.242 1.00 79.09  ? 203 ASP   A OD2   1 
ATOM   1744 N N     . ARG   C 2 192 ? 218.275 207.651 228.767 1.00 68.04  ? 204 ARG   A N     1 
ATOM   1745 C CA    . ARG   C 2 192 ? 219.430 208.208 228.074 1.00 69.97  ? 204 ARG   A CA    1 
ATOM   1746 C C     . ARG   C 2 192 ? 219.440 207.905 226.584 1.00 69.84  ? 204 ARG   A C     1 
ATOM   1747 O O     . ARG   C 2 192 ? 220.251 208.492 225.861 1.00 66.55  ? 204 ARG   A O     1 
ATOM   1748 C CB    . ARG   C 2 192 ? 220.724 207.699 228.704 1.00 80.95  ? 204 ARG   A CB    1 
ATOM   1749 C CG    . ARG   C 2 192 ? 220.972 208.194 230.112 1.00 93.03  ? 204 ARG   A CG    1 
ATOM   1750 C CD    . ARG   C 2 192 ? 222.301 207.671 230.623 1.00 112.76 ? 204 ARG   A CD    1 
ATOM   1751 N NE    . ARG   C 2 192 ? 222.541 208.070 232.005 1.00 123.92 ? 204 ARG   A NE    1 
ATOM   1752 C CZ    . ARG   C 2 192 ? 223.567 207.659 232.737 1.00 120.61 ? 204 ARG   A CZ    1 
ATOM   1753 N NH1   . ARG   C 2 192 ? 224.480 206.836 232.248 1.00 118.91 ? 204 ARG   A NH1   1 
ATOM   1754 N NH2   . ARG   C 2 192 ? 223.682 208.087 233.992 1.00 118.15 ? 204 ARG   A NH2   1 
ATOM   1755 N N     . ASN   C 2 193 ? 218.576 207.010 226.105 1.00 70.30  ? 205 ASN   A N     1 
ATOM   1756 C CA    . ASN   C 2 193 ? 218.473 206.789 224.670 1.00 67.04  ? 205 ASN   A CA    1 
ATOM   1757 C C     . ASN   C 2 193 ? 217.841 207.973 223.953 1.00 68.06  ? 205 ASN   A C     1 
ATOM   1758 O O     . ASN   C 2 193 ? 217.851 208.010 222.720 1.00 70.33  ? 205 ASN   A O     1 
ATOM   1759 C CB    . ASN   C 2 193 ? 217.678 205.517 224.387 1.00 70.49  ? 205 ASN   A CB    1 
ATOM   1760 C CG    . ASN   C 2 193 ? 218.570 204.322 224.139 1.00 78.55  ? 205 ASN   A CG    1 
ATOM   1761 O OD1   . ASN   C 2 193 ? 219.794 204.425 224.209 1.00 79.11  ? 205 ASN   A OD1   1 
ATOM   1762 N ND2   . ASN   C 2 193 ? 217.962 203.181 223.840 1.00 84.12  ? 205 ASN   A ND2   1 
ATOM   1763 N N     . PHE   C 2 194 ? 217.294 208.926 224.699 1.00 67.20  ? 206 PHE   A N     1 
ATOM   1764 C CA    . PHE   C 2 194 ? 216.878 210.213 224.176 1.00 59.91  ? 206 PHE   A CA    1 
ATOM   1765 C C     . PHE   C 2 194 ? 218.093 210.943 223.604 1.00 63.98  ? 206 PHE   A C     1 
ATOM   1766 O O     . PHE   C 2 194 ? 219.238 210.681 223.979 1.00 69.53  ? 206 PHE   A O     1 
ATOM   1767 C CB    . PHE   C 2 194 ? 216.224 211.029 225.290 1.00 61.07  ? 206 PHE   A CB    1 
ATOM   1768 C CG    . PHE   C 2 194 ? 214.994 211.773 224.870 1.00 58.07  ? 206 PHE   A CG    1 
ATOM   1769 C CD1   . PHE   C 2 194 ? 213.822 211.092 224.605 1.00 56.10  ? 206 PHE   A CD1   1 
ATOM   1770 C CD2   . PHE   C 2 194 ? 214.991 213.155 224.793 1.00 56.31  ? 206 PHE   A CD2   1 
ATOM   1771 C CE1   . PHE   C 2 194 ? 212.683 211.767 224.231 1.00 52.86  ? 206 PHE   A CE1   1 
ATOM   1772 C CE2   . PHE   C 2 194 ? 213.851 213.836 224.424 1.00 52.64  ? 206 PHE   A CE2   1 
ATOM   1773 C CZ    . PHE   C 2 194 ? 212.696 213.140 224.145 1.00 52.37  ? 206 PHE   A CZ    1 
ATOM   1774 N N     . TRP   C 2 195 ? 217.832 211.863 222.674 1.00 61.24  ? 207 TRP   A N     1 
ATOM   1775 C CA    . TRP   C 2 195 ? 218.892 212.599 221.977 1.00 63.17  ? 207 TRP   A CA    1 
ATOM   1776 C C     . TRP   C 2 195 ? 219.826 211.662 221.215 1.00 67.09  ? 207 TRP   A C     1 
ATOM   1777 O O     . TRP   C 2 195 ? 221.014 211.949 221.053 1.00 72.49  ? 207 TRP   A O     1 
ATOM   1778 C CB    . TRP   C 2 195 ? 219.706 213.469 222.941 1.00 57.74  ? 207 TRP   A CB    1 
ATOM   1779 C CG    . TRP   C 2 195 ? 218.914 214.116 224.026 1.00 57.26  ? 207 TRP   A CG    1 
ATOM   1780 C CD1   . TRP   C 2 195 ? 218.866 213.749 225.336 1.00 57.48  ? 207 TRP   A CD1   1 
ATOM   1781 C CD2   . TRP   C 2 195 ? 218.077 215.269 223.899 1.00 56.53  ? 207 TRP   A CD2   1 
ATOM   1782 N NE1   . TRP   C 2 195 ? 218.038 214.594 226.033 1.00 58.04  ? 207 TRP   A NE1   1 
ATOM   1783 C CE2   . TRP   C 2 195 ? 217.543 215.537 225.171 1.00 53.76  ? 207 TRP   A CE2   1 
ATOM   1784 C CE3   . TRP   C 2 195 ? 217.724 216.097 222.831 1.00 57.06  ? 207 TRP   A CE3   1 
ATOM   1785 C CZ2   . TRP   C 2 195 ? 216.674 216.596 225.404 1.00 52.47  ? 207 TRP   A CZ2   1 
ATOM   1786 C CZ3   . TRP   C 2 195 ? 216.864 217.145 223.064 1.00 54.60  ? 207 TRP   A CZ3   1 
ATOM   1787 C CH2   . TRP   C 2 195 ? 216.349 217.388 224.340 1.00 54.49  ? 207 TRP   A CH2   1 
ATOM   1788 N N     . ARG   C 2 196 ? 219.306 210.534 220.737 1.00 66.94  ? 208 ARG   A N     1 
ATOM   1789 C CA    . ARG   C 2 196 ? 220.155 209.551 220.077 1.00 62.93  ? 208 ARG   A CA    1 
ATOM   1790 C C     . ARG   C 2 196 ? 219.329 208.701 219.126 1.00 61.71  ? 208 ARG   A C     1 
ATOM   1791 O O     . ARG   C 2 196 ? 218.334 208.096 219.537 1.00 61.00  ? 208 ARG   A O     1 
ATOM   1792 C CB    . ARG   C 2 196 ? 220.858 208.667 221.109 1.00 62.82  ? 208 ARG   A CB    1 
ATOM   1793 C CG    . ARG   C 2 196 ? 221.884 207.715 220.524 1.00 72.51  ? 208 ARG   A CG    1 
ATOM   1794 C CD    . ARG   C 2 196 ? 222.547 206.872 221.612 1.00 81.26  ? 208 ARG   A CD    1 
ATOM   1795 N NE    . ARG   C 2 196 ? 222.855 207.608 222.836 1.00 83.51  ? 208 ARG   A NE    1 
ATOM   1796 C CZ    . ARG   C 2 196 ? 223.632 208.682 222.912 1.00 81.97  ? 208 ARG   A CZ    1 
ATOM   1797 N NH1   . ARG   C 2 196 ? 224.258 209.165 221.852 1.00 84.82  ? 208 ARG   A NH1   1 
ATOM   1798 N NH2   . ARG   C 2 196 ? 223.799 209.278 224.090 1.00 79.94  ? 208 ARG   A NH2   1 
ATOM   1799 N N     . GLY   C 2 197 ? 219.754 208.642 217.871 1.00 56.68  ? 209 GLY   A N     1 
ATOM   1800 C CA    . GLY   C 2 197 ? 219.086 207.849 216.860 1.00 55.56  ? 209 GLY   A CA    1 
ATOM   1801 C C     . GLY   C 2 197 ? 218.233 208.681 215.926 1.00 59.49  ? 209 GLY   A C     1 
ATOM   1802 O O     . GLY   C 2 197 ? 218.381 209.900 215.808 1.00 60.56  ? 209 GLY   A O     1 
ATOM   1803 N N     . GLU   C 2 198 ? 217.317 207.994 215.240 1.00 62.92  ? 210 GLU   A N     1 
ATOM   1804 C CA    . GLU   C 2 198 ? 216.402 208.690 214.342 1.00 65.68  ? 210 GLU   A CA    1 
ATOM   1805 C C     . GLU   C 2 198 ? 215.466 209.604 215.122 1.00 69.86  ? 210 GLU   A C     1 
ATOM   1806 O O     . GLU   C 2 198 ? 215.239 210.753 214.723 1.00 69.58  ? 210 GLU   A O     1 
ATOM   1807 C CB    . GLU   C 2 198 ? 215.650 207.665 213.472 1.00 75.47  ? 210 GLU   A CB    1 
ATOM   1808 C CG    . GLU   C 2 198 ? 214.358 208.094 212.723 1.00 86.52  ? 210 GLU   A CG    1 
ATOM   1809 C CD    . GLU   C 2 198 ? 213.168 208.465 213.604 1.00 90.47  ? 210 GLU   A CD    1 
ATOM   1810 O OE1   . GLU   C 2 198 ? 213.133 208.055 214.783 1.00 84.87  ? 210 GLU   A OE1   1 
ATOM   1811 O OE2   . GLU   C 2 198 ? 212.258 209.164 213.109 1.00 95.42  ? 210 GLU   A OE2   1 
ATOM   1812 N N     . ASN   C 2 199 ? 214.906 209.112 216.231 1.00 70.47  ? 211 ASN   A N     1 
ATOM   1813 C CA    . ASN   C 2 199 ? 214.100 209.971 217.094 1.00 68.23  ? 211 ASN   A CA    1 
ATOM   1814 C C     . ASN   C 2 199 ? 214.946 211.050 217.751 1.00 61.22  ? 211 ASN   A C     1 
ATOM   1815 O O     . ASN   C 2 199 ? 214.431 212.122 218.088 1.00 61.80  ? 211 ASN   A O     1 
ATOM   1816 C CB    . ASN   C 2 199 ? 213.391 209.139 218.162 1.00 67.02  ? 211 ASN   A CB    1 
ATOM   1817 C CG    . ASN   C 2 199 ? 214.250 208.010 218.684 1.00 73.09  ? 211 ASN   A CG    1 
ATOM   1818 O OD1   . ASN   C 2 199 ? 215.478 208.090 218.671 1.00 71.55  ? 211 ASN   A OD1   1 
ATOM   1819 N ND2   . ASN   C 2 199 ? 213.606 206.955 219.169 1.00 79.82  ? 211 ASN   A ND2   1 
ATOM   1820 N N     . GLY   C 2 200 ? 216.233 210.773 217.969 1.00 58.17  ? 212 GLY   A N     1 
ATOM   1821 C CA    . GLY   C 2 200 ? 217.120 211.785 218.521 1.00 59.01  ? 212 GLY   A CA    1 
ATOM   1822 C C     . GLY   C 2 200 ? 217.222 213.012 217.642 1.00 61.55  ? 212 GLY   A C     1 
ATOM   1823 O O     . GLY   C 2 200 ? 217.248 214.141 218.132 1.00 62.73  ? 212 GLY   A O     1 
ATOM   1824 N N     . ARG   C 2 201 ? 217.283 212.806 216.325 1.00 63.00  ? 213 ARG   A N     1 
ATOM   1825 C CA    . ARG   C 2 201 ? 217.314 213.928 215.391 1.00 63.78  ? 213 ARG   A CA    1 
ATOM   1826 C C     . ARG   C 2 201 ? 216.071 214.794 215.525 1.00 59.14  ? 213 ARG   A C     1 
ATOM   1827 O O     . ARG   C 2 201 ? 216.164 216.022 215.629 1.00 60.07  ? 213 ARG   A O     1 
ATOM   1828 C CB    . ARG   C 2 201 ? 217.437 213.413 213.957 1.00 73.91  ? 213 ARG   A CB    1 
ATOM   1829 C CG    . ARG   C 2 201 ? 218.820 212.931 213.561 1.00 74.37  ? 213 ARG   A CG    1 
ATOM   1830 C CD    . ARG   C 2 201 ? 218.783 212.017 212.330 1.00 78.04  ? 213 ARG   A CD    1 
ATOM   1831 N NE    . ARG   C 2 201 ? 217.712 212.296 211.375 1.00 75.85  ? 213 ARG   A NE    1 
ATOM   1832 C CZ    . ARG   C 2 201 ? 217.548 213.436 210.715 1.00 77.71  ? 213 ARG   A CZ    1 
ATOM   1833 N NH1   . ARG   C 2 201 ? 218.400 214.441 210.843 1.00 77.12  ? 213 ARG   A NH1   1 
ATOM   1834 N NH2   . ARG   C 2 201 ? 216.509 213.566 209.894 1.00 83.30  ? 213 ARG   A NH2   1 
ATOM   1835 N N     . ARG   C 2 202 ? 214.894 214.166 215.512 1.00 56.14  ? 214 ARG   A N     1 
ATOM   1836 C CA    . ARG   C 2 202 ? 213.648 214.915 215.609 1.00 58.22  ? 214 ARG   A CA    1 
ATOM   1837 C C     . ARG   C 2 202 ? 213.549 215.649 216.938 1.00 56.74  ? 214 ARG   A C     1 
ATOM   1838 O O     . ARG   C 2 202 ? 213.131 216.814 216.987 1.00 53.88  ? 214 ARG   A O     1 
ATOM   1839 C CB    . ARG   C 2 202 ? 212.462 213.968 215.427 1.00 64.63  ? 214 ARG   A CB    1 
ATOM   1840 C CG    . ARG   C 2 202 ? 211.114 214.655 215.413 1.00 75.71  ? 214 ARG   A CG    1 
ATOM   1841 C CD    . ARG   C 2 202 ? 209.952 213.849 214.790 1.00 87.66  ? 214 ARG   A CD    1 
ATOM   1842 N NE    . ARG   C 2 202 ? 209.902 212.421 215.105 1.00 97.97  ? 214 ARG   A NE    1 
ATOM   1843 C CZ    . ARG   C 2 202 ? 210.627 211.471 214.526 1.00 95.02  ? 214 ARG   A CZ    1 
ATOM   1844 N NH1   . ARG   C 2 202 ? 211.417 211.731 213.495 1.00 87.35  ? 214 ARG   A NH1   1 
ATOM   1845 N NH2   . ARG   C 2 202 ? 210.532 210.222 214.972 1.00 96.24  ? 214 ARG   A NH2   1 
ATOM   1846 N N     . THR   C 2 203 ? 213.926 214.984 218.032 1.00 58.52  ? 215 THR   A N     1 
ATOM   1847 C CA    . THR   C 2 203 ? 213.839 215.614 219.343 1.00 55.24  ? 215 THR   A CA    1 
ATOM   1848 C C     . THR   C 2 203 ? 214.813 216.777 219.459 1.00 52.39  ? 215 THR   A C     1 
ATOM   1849 O O     . THR   C 2 203 ? 214.475 217.820 220.029 1.00 53.01  ? 215 THR   A O     1 
ATOM   1850 C CB    . THR   C 2 203 ? 214.090 214.583 220.441 1.00 56.60  ? 215 THR   A CB    1 
ATOM   1851 O OG1   . THR   C 2 203 ? 215.211 213.767 220.086 1.00 63.64  ? 215 THR   A OG1   1 
ATOM   1852 C CG2   . THR   C 2 203 ? 212.869 213.697 220.610 1.00 50.64  ? 215 THR   A CG2   1 
ATOM   1853 N N     . ARG   C 2 204 ? 216.025 216.624 218.920 1.00 51.36  ? 216 ARG   A N     1 
ATOM   1854 C CA    . ARG   C 2 204 ? 216.973 217.732 218.916 1.00 50.42  ? 216 ARG   A CA    1 
ATOM   1855 C C     . ARG   C 2 204 ? 216.465 218.890 218.069 1.00 50.32  ? 216 ARG   A C     1 
ATOM   1856 O O     . ARG   C 2 204 ? 216.635 220.053 218.442 1.00 50.24  ? 216 ARG   A O     1 
ATOM   1857 C CB    . ARG   C 2 204 ? 218.339 217.257 218.420 1.00 54.51  ? 216 ARG   A CB    1 
ATOM   1858 C CG    . ARG   C 2 204 ? 219.433 218.317 218.489 1.00 49.95  ? 216 ARG   A CG    1 
ATOM   1859 C CD    . ARG   C 2 204 ? 219.317 219.154 219.746 1.00 48.73  ? 216 ARG   A CD    1 
ATOM   1860 N NE    . ARG   C 2 204 ? 220.283 220.243 219.764 1.00 50.63  ? 216 ARG   A NE    1 
ATOM   1861 C CZ    . ARG   C 2 204 ? 221.262 220.357 220.647 1.00 54.51  ? 216 ARG   A CZ    1 
ATOM   1862 N NH1   . ARG   C 2 204 ? 221.416 219.478 221.622 1.00 56.62  ? 216 ARG   A NH1   1 
ATOM   1863 N NH2   . ARG   C 2 204 ? 222.102 221.382 220.555 1.00 57.75  ? 216 ARG   A NH2   1 
ATOM   1864 N N     . ILE   C 2 205 ? 215.841 218.597 216.927 1.00 53.08  ? 217 ILE   A N     1 
ATOM   1865 C CA    . ILE   C 2 205 ? 215.299 219.662 216.087 1.00 50.25  ? 217 ILE   A CA    1 
ATOM   1866 C C     . ILE   C 2 205 ? 214.215 220.428 216.835 1.00 48.59  ? 217 ILE   A C     1 
ATOM   1867 O O     . ILE   C 2 205 ? 214.203 221.667 216.851 1.00 48.86  ? 217 ILE   A O     1 
ATOM   1868 C CB    . ILE   C 2 205 ? 214.774 219.077 214.763 1.00 53.44  ? 217 ILE   A CB    1 
ATOM   1869 C CG1   . ILE   C 2 205 ? 215.922 218.878 213.774 1.00 50.17  ? 217 ILE   A CG1   1 
ATOM   1870 C CG2   . ILE   C 2 205 ? 213.707 219.977 214.160 1.00 58.40  ? 217 ILE   A CG2   1 
ATOM   1871 C CD1   . ILE   C 2 205 ? 215.472 218.421 212.407 1.00 54.65  ? 217 ILE   A CD1   1 
ATOM   1872 N N     . ALA   C 2 206 ? 213.297 219.702 217.478 1.00 50.17  ? 218 ALA   A N     1 
ATOM   1873 C CA    . ALA   C 2 206 ? 212.234 220.355 218.234 1.00 49.74  ? 218 ALA   A CA    1 
ATOM   1874 C C     . ALA   C 2 206 ? 212.800 221.170 219.390 1.00 51.73  ? 218 ALA   A C     1 
ATOM   1875 O O     . ALA   C 2 206 ? 212.354 222.296 219.642 1.00 56.43  ? 218 ALA   A O     1 
ATOM   1876 C CB    . ALA   C 2 206 ? 211.238 219.315 218.746 1.00 47.61  ? 218 ALA   A CB    1 
ATOM   1877 N N     . TYR   C 2 207 ? 213.779 220.613 220.107 1.00 48.97  ? 219 TYR   A N     1 
ATOM   1878 C CA    . TYR   C 2 207 ? 214.431 221.335 221.195 1.00 48.09  ? 219 TYR   A CA    1 
ATOM   1879 C C     . TYR   C 2 207 ? 215.062 222.624 220.689 1.00 49.16  ? 219 TYR   A C     1 
ATOM   1880 O O     . TYR   C 2 207 ? 214.876 223.696 221.279 1.00 52.19  ? 219 TYR   A O     1 
ATOM   1881 C CB    . TYR   C 2 207 ? 215.481 220.426 221.839 1.00 50.80  ? 219 TYR   A CB    1 
ATOM   1882 C CG    . TYR   C 2 207 ? 216.222 221.013 223.017 1.00 50.87  ? 219 TYR   A CG    1 
ATOM   1883 C CD1   . TYR   C 2 207 ? 215.553 221.400 224.167 1.00 49.71  ? 219 TYR   A CD1   1 
ATOM   1884 C CD2   . TYR   C 2 207 ? 217.601 221.161 222.984 1.00 51.15  ? 219 TYR   A CD2   1 
ATOM   1885 C CE1   . TYR   C 2 207 ? 216.235 221.928 225.245 1.00 52.03  ? 219 TYR   A CE1   1 
ATOM   1886 C CE2   . TYR   C 2 207 ? 218.290 221.686 224.055 1.00 51.73  ? 219 TYR   A CE2   1 
ATOM   1887 C CZ    . TYR   C 2 207 ? 217.603 222.068 225.182 1.00 53.81  ? 219 TYR   A CZ    1 
ATOM   1888 O OH    . TYR   C 2 207 ? 218.288 222.594 226.252 1.00 57.18  ? 219 TYR   A OH    1 
ATOM   1889 N N     . GLU   C 2 208 ? 215.805 222.533 219.582 1.00 48.71  ? 220 GLU   A N     1 
ATOM   1890 C CA    . GLU   C 2 208 ? 216.394 223.704 218.947 1.00 46.99  ? 220 GLU   A CA    1 
ATOM   1891 C C     . GLU   C 2 208 ? 215.342 224.764 218.673 1.00 46.16  ? 220 GLU   A C     1 
ATOM   1892 O O     . GLU   C 2 208 ? 215.525 225.938 219.002 1.00 45.63  ? 220 GLU   A O     1 
ATOM   1893 C CB    . GLU   C 2 208 ? 217.071 223.300 217.634 1.00 50.72  ? 220 GLU   A CB    1 
ATOM   1894 C CG    . GLU   C 2 208 ? 218.399 222.582 217.760 1.00 50.83  ? 220 GLU   A CG    1 
ATOM   1895 C CD    . GLU   C 2 208 ? 219.399 223.332 218.601 1.00 57.96  ? 220 GLU   A CD    1 
ATOM   1896 O OE1   . GLU   C 2 208 ? 220.099 224.203 218.047 1.00 59.29  ? 220 GLU   A OE1   1 
ATOM   1897 O OE2   . GLU   C 2 208 ? 219.497 223.039 219.809 1.00 62.65  ? 220 GLU   A OE2   1 
ATOM   1898 N N     . ARG   C 2 209 ? 214.229 224.362 218.057 1.00 48.89  ? 221 ARG   A N     1 
ATOM   1899 C CA    . ARG   C 2 209 ? 213.253 225.339 217.588 1.00 50.99  ? 221 ARG   A CA    1 
ATOM   1900 C C     . ARG   C 2 209 ? 212.548 226.017 218.761 1.00 50.23  ? 221 ARG   A C     1 
ATOM   1901 O O     . ARG   C 2 209 ? 212.397 227.247 218.791 1.00 52.46  ? 221 ARG   A O     1 
ATOM   1902 C CB    . ARG   C 2 209 ? 212.248 224.661 216.654 1.00 54.84  ? 221 ARG   A CB    1 
ATOM   1903 C CG    . ARG   C 2 209 ? 212.786 224.480 215.241 1.00 66.35  ? 221 ARG   A CG    1 
ATOM   1904 C CD    . ARG   C 2 209 ? 212.628 225.724 214.385 1.00 83.55  ? 221 ARG   A CD    1 
ATOM   1905 N NE    . ARG   C 2 209 ? 211.242 226.153 214.261 1.00 104.69 ? 221 ARG   A NE    1 
ATOM   1906 C CZ    . ARG   C 2 209 ? 210.833 227.127 213.461 1.00 118.88 ? 221 ARG   A CZ    1 
ATOM   1907 N NH1   . ARG   C 2 209 ? 211.683 227.811 212.716 1.00 118.57 ? 221 ARG   A NH1   1 
ATOM   1908 N NH2   . ARG   C 2 209 ? 209.537 227.419 213.402 1.00 118.16 ? 221 ARG   A NH2   1 
ATOM   1909 N N     . MET   C 2 210 ? 212.115 225.224 219.747 1.00 47.12  ? 222 MET   A N     1 
ATOM   1910 C CA    . MET   C 2 210 ? 211.466 225.815 220.913 1.00 48.05  ? 222 MET   A CA    1 
ATOM   1911 C C     . MET   C 2 210 ? 212.416 226.722 221.680 1.00 49.43  ? 222 MET   A C     1 
ATOM   1912 O O     . MET   C 2 210 ? 212.012 227.801 222.132 1.00 50.90  ? 222 MET   A O     1 
ATOM   1913 C CB    . MET   C 2 210 ? 210.902 224.727 221.831 1.00 43.42  ? 222 MET   A CB    1 
ATOM   1914 C CG    . MET   C 2 210 ? 210.109 223.654 221.106 1.00 49.55  ? 222 MET   A CG    1 
ATOM   1915 S SD    . MET   C 2 210 ? 209.696 222.213 222.109 1.00 53.60  ? 222 MET   A SD    1 
ATOM   1916 C CE    . MET   C 2 210 ? 210.173 222.768 223.739 1.00 45.03  ? 222 MET   A CE    1 
ATOM   1917 N N     . CYS   C 2 211 ? 213.686 226.333 221.805 1.00 48.37  ? 223 CYS   A N     1 
ATOM   1918 C CA    . CYS   C 2 211 ? 214.627 227.198 222.503 1.00 47.24  ? 223 CYS   A CA    1 
ATOM   1919 C C     . CYS   C 2 211 ? 214.905 228.472 221.713 1.00 48.95  ? 223 CYS   A C     1 
ATOM   1920 O O     . CYS   C 2 211 ? 215.067 229.543 222.304 1.00 48.65  ? 223 CYS   A O     1 
ATOM   1921 C CB    . CYS   C 2 211 ? 215.924 226.442 222.784 1.00 49.66  ? 223 CYS   A CB    1 
ATOM   1922 S SG    . CYS   C 2 211 ? 216.885 227.141 224.135 1.00 70.24  ? 223 CYS   A SG    1 
ATOM   1923 N N     . ASN   C 2 212 ? 214.945 228.382 220.382 1.00 49.84  ? 224 ASN   A N     1 
ATOM   1924 C CA    . ASN   C 2 212 ? 215.144 229.573 219.564 1.00 47.57  ? 224 ASN   A CA    1 
ATOM   1925 C C     . ASN   C 2 212 ? 213.996 230.558 219.728 1.00 45.24  ? 224 ASN   A C     1 
ATOM   1926 O O     . ASN   C 2 212 ? 214.214 231.772 219.837 1.00 46.76  ? 224 ASN   A O     1 
ATOM   1927 C CB    . ASN   C 2 212 ? 215.298 229.190 218.092 1.00 48.25  ? 224 ASN   A CB    1 
ATOM   1928 C CG    . ASN   C 2 212 ? 216.643 228.567 217.786 1.00 51.15  ? 224 ASN   A CG    1 
ATOM   1929 O OD1   . ASN   C 2 212 ? 217.617 228.783 218.503 1.00 54.60  ? 224 ASN   A OD1   1 
ATOM   1930 N ND2   . ASN   C 2 212 ? 216.704 227.794 216.709 1.00 48.60  ? 224 ASN   A ND2   1 
ATOM   1931 N N     . ILE   C 2 213 ? 212.758 230.061 219.744 1.00 44.16  ? 225 ILE   A N     1 
ATOM   1932 C CA    . ILE   C 2 213 ? 211.652 231.008 219.847 1.00 48.13  ? 225 ILE   A CA    1 
ATOM   1933 C C     . ILE   C 2 213 ? 211.498 231.517 221.279 1.00 45.60  ? 225 ILE   A C     1 
ATOM   1934 O O     . ILE   C 2 213 ? 211.032 232.645 221.496 1.00 44.63  ? 225 ILE   A O     1 
ATOM   1935 C CB    . ILE   C 2 213 ? 210.357 230.394 219.286 1.00 49.90  ? 225 ILE   A CB    1 
ATOM   1936 C CG1   . ILE   C 2 213 ? 209.716 229.447 220.287 1.00 44.50  ? 225 ILE   A CG1   1 
ATOM   1937 C CG2   . ILE   C 2 213 ? 210.650 229.666 217.990 1.00 52.32  ? 225 ILE   A CG2   1 
ATOM   1938 C CD1   . ILE   C 2 213 ? 208.575 228.647 219.720 1.00 43.89  ? 225 ILE   A CD1   1 
ATOM   1939 N N     . LEU   C 2 214 ? 211.921 230.733 222.276 1.00 44.94  ? 226 LEU   A N     1 
ATOM   1940 C CA    . LEU   C 2 214 ? 212.025 231.272 223.630 1.00 43.39  ? 226 LEU   A CA    1 
ATOM   1941 C C     . LEU   C 2 214 ? 213.079 232.372 223.696 1.00 43.51  ? 226 LEU   A C     1 
ATOM   1942 O O     . LEU   C 2 214 ? 212.905 233.373 224.402 1.00 42.75  ? 226 LEU   A O     1 
ATOM   1943 C CB    . LEU   C 2 214 ? 212.357 230.157 224.620 1.00 44.60  ? 226 LEU   A CB    1 
ATOM   1944 C CG    . LEU   C 2 214 ? 212.696 230.598 226.047 1.00 43.55  ? 226 LEU   A CG    1 
ATOM   1945 C CD1   . LEU   C 2 214 ? 211.564 231.409 226.648 1.00 42.50  ? 226 LEU   A CD1   1 
ATOM   1946 C CD2   . LEU   C 2 214 ? 213.015 229.403 226.922 1.00 45.89  ? 226 LEU   A CD2   1 
ATOM   1947 N N     . LYS   C 2 215 ? 214.187 232.192 222.976 1.00 46.31  ? 227 LYS   A N     1 
ATOM   1948 C CA    . LYS   C 2 215 ? 215.202 233.234 222.880 1.00 46.54  ? 227 LYS   A CA    1 
ATOM   1949 C C     . LYS   C 2 215 ? 214.628 234.499 222.261 1.00 45.06  ? 227 LYS   A C     1 
ATOM   1950 O O     . LYS   C 2 215 ? 214.865 235.608 222.752 1.00 44.54  ? 227 LYS   A O     1 
ATOM   1951 C CB    . LYS   C 2 215 ? 216.383 232.721 222.056 1.00 45.31  ? 227 LYS   A CB    1 
ATOM   1952 C CG    . LYS   C 2 215 ? 217.490 233.726 221.858 1.00 40.92  ? 227 LYS   A CG    1 
ATOM   1953 C CD    . LYS   C 2 215 ? 218.161 233.551 220.512 1.00 41.55  ? 227 LYS   A CD    1 
ATOM   1954 C CE    . LYS   C 2 215 ? 219.482 234.293 220.458 1.00 46.54  ? 227 LYS   A CE    1 
ATOM   1955 N NZ    . LYS   C 2 215 ? 220.512 233.650 221.313 1.00 54.56  ? 227 LYS   A NZ    1 
ATOM   1956 N N     . GLY   C 2 216 ? 213.867 234.347 221.179 1.00 45.74  ? 228 GLY   A N     1 
ATOM   1957 C CA    . GLY   C 2 216 ? 213.208 235.486 220.570 1.00 43.39  ? 228 GLY   A CA    1 
ATOM   1958 C C     . GLY   C 2 216 ? 212.160 236.125 221.456 1.00 44.00  ? 228 GLY   A C     1 
ATOM   1959 O O     . GLY   C 2 216 ? 211.831 237.299 221.268 1.00 47.41  ? 228 GLY   A O     1 
ATOM   1960 N N     . LYS   C 2 217 ? 211.626 235.375 222.421 1.00 45.37  ? 229 LYS   A N     1 
ATOM   1961 C CA    . LYS   C 2 217 ? 210.604 235.927 223.303 1.00 43.15  ? 229 LYS   A CA    1 
ATOM   1962 C C     . LYS   C 2 217 ? 211.185 236.902 224.324 1.00 44.46  ? 229 LYS   A C     1 
ATOM   1963 O O     . LYS   C 2 217 ? 210.486 237.824 224.760 1.00 47.95  ? 229 LYS   A O     1 
ATOM   1964 C CB    . LYS   C 2 217 ? 209.866 234.789 224.006 1.00 41.91  ? 229 LYS   A CB    1 
ATOM   1965 C CG    . LYS   C 2 217 ? 208.591 235.204 224.700 1.00 44.40  ? 229 LYS   A CG    1 
ATOM   1966 C CD    . LYS   C 2 217 ? 207.668 234.018 224.891 1.00 44.99  ? 229 LYS   A CD    1 
ATOM   1967 C CE    . LYS   C 2 217 ? 207.128 233.535 223.562 1.00 42.74  ? 229 LYS   A CE    1 
ATOM   1968 N NZ    . LYS   C 2 217 ? 206.546 234.652 222.774 1.00 40.60  ? 229 LYS   A NZ    1 
ATOM   1969 N N     . PHE   C 2 218 ? 212.445 236.726 224.714 1.00 46.56  ? 230 PHE   A N     1 
ATOM   1970 C CA    . PHE   C 2 218 ? 213.015 237.532 225.785 1.00 43.40  ? 230 PHE   A CA    1 
ATOM   1971 C C     . PHE   C 2 218 ? 213.328 238.943 225.289 1.00 47.93  ? 230 PHE   A C     1 
ATOM   1972 O O     . PHE   C 2 218 ? 213.221 239.259 224.102 1.00 53.39  ? 230 PHE   A O     1 
ATOM   1973 C CB    . PHE   C 2 218 ? 214.266 236.861 226.348 1.00 44.14  ? 230 PHE   A CB    1 
ATOM   1974 C CG    . PHE   C 2 218 ? 213.981 235.885 227.449 1.00 44.55  ? 230 PHE   A CG    1 
ATOM   1975 C CD1   . PHE   C 2 218 ? 213.351 236.296 228.609 1.00 42.72  ? 230 PHE   A CD1   1 
ATOM   1976 C CD2   . PHE   C 2 218 ? 214.344 234.558 227.324 1.00 46.19  ? 230 PHE   A CD2   1 
ATOM   1977 C CE1   . PHE   C 2 218 ? 213.086 235.399 229.621 1.00 43.29  ? 230 PHE   A CE1   1 
ATOM   1978 C CE2   . PHE   C 2 218 ? 214.084 233.661 228.334 1.00 44.35  ? 230 PHE   A CE2   1 
ATOM   1979 C CZ    . PHE   C 2 218 ? 213.454 234.081 229.483 1.00 43.16  ? 230 PHE   A CZ    1 
ATOM   1980 N N     . GLN   C 2 219 ? 213.722 239.806 226.226 1.00 46.93  ? 231 GLN   A N     1 
ATOM   1981 C CA    . GLN   C 2 219 ? 213.925 241.223 225.954 1.00 47.56  ? 231 GLN   A CA    1 
ATOM   1982 C C     . GLN   C 2 219 ? 215.383 241.640 226.102 1.00 47.76  ? 231 GLN   A C     1 
ATOM   1983 O O     . GLN   C 2 219 ? 215.961 242.213 225.176 1.00 47.04  ? 231 GLN   A O     1 
ATOM   1984 C CB    . GLN   C 2 219 ? 213.040 242.061 226.887 1.00 49.09  ? 231 GLN   A CB    1 
ATOM   1985 C CG    . GLN   C 2 219 ? 211.557 242.030 226.558 1.00 50.68  ? 231 GLN   A CG    1 
ATOM   1986 C CD    . GLN   C 2 219 ? 211.173 242.976 225.444 1.00 50.23  ? 231 GLN   A CD    1 
ATOM   1987 O OE1   . GLN   C 2 219 ? 211.862 243.080 224.429 1.00 50.32  ? 231 GLN   A OE1   1 
ATOM   1988 N NE2   . GLN   C 2 219 ? 210.066 243.683 225.629 1.00 50.47  ? 231 GLN   A NE2   1 
ATOM   1989 N N     . THR   C 2 220 ? 215.994 241.370 227.251 1.00 51.21  ? 232 THR   A N     1 
ATOM   1990 C CA    . THR   C 2 220 ? 217.350 241.826 227.508 1.00 48.27  ? 232 THR   A CA    1 
ATOM   1991 C C     . THR   C 2 220 ? 218.373 240.837 226.958 1.00 47.50  ? 232 THR   A C     1 
ATOM   1992 O O     . THR   C 2 220 ? 218.090 239.654 226.749 1.00 48.46  ? 232 THR   A O     1 
ATOM   1993 C CB    . THR   C 2 220 ? 217.574 242.039 229.006 1.00 46.83  ? 232 THR   A CB    1 
ATOM   1994 O OG1   . THR   C 2 220 ? 218.960 242.306 229.248 1.00 52.85  ? 232 THR   A OG1   1 
ATOM   1995 C CG2   . THR   C 2 220 ? 217.167 240.810 229.782 1.00 45.80  ? 232 THR   A CG2   1 
ATOM   1996 N N     . ALA   C 2 221 ? 219.585 241.345 226.729 1.00 46.21  ? 233 ALA   A N     1 
ATOM   1997 C CA    . ALA   C 2 221 ? 220.610 240.560 226.047 1.00 46.71  ? 233 ALA   A CA    1 
ATOM   1998 C C     . ALA   C 2 221 ? 221.134 239.428 226.923 1.00 44.81  ? 233 ALA   A C     1 
ATOM   1999 O O     . ALA   C 2 221 ? 221.511 238.369 226.412 1.00 45.82  ? 233 ALA   A O     1 
ATOM   2000 C CB    . ALA   C 2 221 ? 221.756 241.469 225.608 1.00 47.08  ? 233 ALA   A CB    1 
ATOM   2001 N N     . ALA   C 2 222 ? 221.187 239.637 228.240 1.00 41.46  ? 234 ALA   A N     1 
ATOM   2002 C CA    . ALA   C 2 222 ? 221.750 238.624 229.127 1.00 44.60  ? 234 ALA   A CA    1 
ATOM   2003 C C     . ALA   C 2 222 ? 220.893 237.363 229.150 1.00 45.34  ? 234 ALA   A C     1 
ATOM   2004 O O     . ALA   C 2 222 ? 221.413 236.241 229.092 1.00 46.20  ? 234 ALA   A O     1 
ATOM   2005 C CB    . ALA   C 2 222 ? 221.913 239.201 230.532 1.00 45.65  ? 234 ALA   A CB    1 
ATOM   2006 N N     . GLN   C 2 223 ? 219.572 237.525 229.242 1.00 43.84  ? 235 GLN   A N     1 
ATOM   2007 C CA    . GLN   C 2 223 ? 218.677 236.373 229.168 1.00 42.90  ? 235 GLN   A CA    1 
ATOM   2008 C C     . GLN   C 2 223 ? 218.768 235.702 227.807 1.00 44.25  ? 235 GLN   A C     1 
ATOM   2009 O O     . GLN   C 2 223 ? 218.771 234.466 227.702 1.00 44.20  ? 235 GLN   A O     1 
ATOM   2010 C CB    . GLN   C 2 223 ? 217.239 236.813 229.448 1.00 42.09  ? 235 GLN   A CB    1 
ATOM   2011 C CG    . GLN   C 2 223 ? 217.000 237.321 230.856 1.00 42.10  ? 235 GLN   A CG    1 
ATOM   2012 C CD    . GLN   C 2 223 ? 215.623 237.922 231.036 1.00 42.06  ? 235 GLN   A CD    1 
ATOM   2013 O OE1   . GLN   C 2 223 ? 215.043 238.466 230.099 1.00 41.82  ? 235 GLN   A OE1   1 
ATOM   2014 N NE2   . GLN   C 2 223 ? 215.091 237.825 232.245 1.00 44.33  ? 235 GLN   A NE2   1 
ATOM   2015 N N     . ARG   C 2 224 ? 218.842 236.512 226.750 1.00 45.97  ? 236 ARG   A N     1 
ATOM   2016 C CA    . ARG   C 2 224 ? 218.954 236.012 225.388 1.00 45.30  ? 236 ARG   A CA    1 
ATOM   2017 C C     . ARG   C 2 224 ? 220.245 235.234 225.165 1.00 46.04  ? 236 ARG   A C     1 
ATOM   2018 O O     . ARG   C 2 224 ? 220.287 234.361 224.291 1.00 46.44  ? 236 ARG   A O     1 
ATOM   2019 C CB    . ARG   C 2 224 ? 218.858 237.194 224.421 1.00 46.15  ? 236 ARG   A CB    1 
ATOM   2020 C CG    . ARG   C 2 224 ? 218.466 236.836 223.010 1.00 50.61  ? 236 ARG   A CG    1 
ATOM   2021 C CD    . ARG   C 2 224 ? 218.750 237.986 222.060 1.00 53.02  ? 236 ARG   A CD    1 
ATOM   2022 N NE    . ARG   C 2 224 ? 218.031 239.198 222.431 1.00 44.88  ? 236 ARG   A NE    1 
ATOM   2023 C CZ    . ARG   C 2 224 ? 216.726 239.376 222.278 1.00 44.06  ? 236 ARG   A CZ    1 
ATOM   2024 N NH1   . ARG   C 2 224 ? 215.956 238.436 221.754 1.00 42.35  ? 236 ARG   A NH1   1 
ATOM   2025 N NH2   . ARG   C 2 224 ? 216.179 240.526 222.655 1.00 49.70  ? 236 ARG   A NH2   1 
ATOM   2026 N N     . THR   C 2 225 ? 221.294 235.529 225.928 1.00 47.20  ? 237 THR   A N     1 
ATOM   2027 C CA    . THR   C 2 225 ? 222.543 234.783 225.834 1.00 46.90  ? 237 THR   A CA    1 
ATOM   2028 C C     . THR   C 2 225 ? 222.542 233.544 226.718 1.00 47.37  ? 237 THR   A C     1 
ATOM   2029 O O     . THR   C 2 225 ? 223.110 232.514 226.338 1.00 49.93  ? 237 THR   A O     1 
ATOM   2030 C CB    . THR   C 2 225 ? 223.731 235.674 226.205 1.00 47.26  ? 237 THR   A CB    1 
ATOM   2031 O OG1   . THR   C 2 225 ? 223.465 236.338 227.445 1.00 51.86  ? 237 THR   A OG1   1 
ATOM   2032 C CG2   . THR   C 2 225 ? 223.983 236.709 225.123 1.00 49.77  ? 237 THR   A CG2   1 
ATOM   2033 N N     . MET   C 2 226 ? 221.921 233.617 227.898 1.00 48.12  ? 238 MET   A N     1 
ATOM   2034 C CA    . MET   C 2 226 ? 221.849 232.427 228.741 1.00 48.32  ? 238 MET   A CA    1 
ATOM   2035 C C     . MET   C 2 226 ? 221.000 231.345 228.088 1.00 46.52  ? 238 MET   A C     1 
ATOM   2036 O O     . MET   C 2 226 ? 221.324 230.155 228.181 1.00 47.00  ? 238 MET   A O     1 
ATOM   2037 C CB    . MET   C 2 226 ? 221.296 232.757 230.125 1.00 44.41  ? 238 MET   A CB    1 
ATOM   2038 C CG    . MET   C 2 226 ? 221.316 231.543 231.046 1.00 47.18  ? 238 MET   A CG    1 
ATOM   2039 S SD    . MET   C 2 226 ? 221.348 231.920 232.801 1.00 51.41  ? 238 MET   A SD    1 
ATOM   2040 C CE    . MET   C 2 226 ? 220.107 233.193 232.856 1.00 45.57  ? 238 MET   A CE    1 
ATOM   2041 N N     . VAL   C 2 227 ? 219.905 231.731 227.432 1.00 46.41  ? 239 VAL   A N     1 
ATOM   2042 C CA    . VAL   C 2 227 ? 219.092 230.731 226.748 1.00 46.26  ? 239 VAL   A CA    1 
ATOM   2043 C C     . VAL   C 2 227 ? 219.875 230.098 225.601 1.00 48.85  ? 239 VAL   A C     1 
ATOM   2044 O O     . VAL   C 2 227 ? 219.753 228.896 225.333 1.00 53.35  ? 239 VAL   A O     1 
ATOM   2045 C CB    . VAL   C 2 227 ? 217.758 231.350 226.285 1.00 43.98  ? 239 VAL   A CB    1 
ATOM   2046 C CG1   . VAL   C 2 227 ? 217.976 232.348 225.175 1.00 49.00  ? 239 VAL   A CG1   1 
ATOM   2047 C CG2   . VAL   C 2 227 ? 216.793 230.265 225.845 1.00 43.71  ? 239 VAL   A CG2   1 
ATOM   2048 N N     . ASP   C 2 228 ? 220.715 230.887 224.926 1.00 49.24  ? 240 ASP   A N     1 
ATOM   2049 C CA    . ASP   C 2 228 ? 221.574 230.340 223.883 1.00 52.57  ? 240 ASP   A CA    1 
ATOM   2050 C C     . ASP   C 2 228 ? 222.590 229.365 224.465 1.00 52.77  ? 240 ASP   A C     1 
ATOM   2051 O O     . ASP   C 2 228 ? 222.885 228.329 223.860 1.00 52.68  ? 240 ASP   A O     1 
ATOM   2052 C CB    . ASP   C 2 228 ? 222.274 231.475 223.140 1.00 57.78  ? 240 ASP   A CB    1 
ATOM   2053 C CG    . ASP   C 2 228 ? 222.526 231.150 221.686 1.00 66.21  ? 240 ASP   A CG    1 
ATOM   2054 O OD1   . ASP   C 2 228 ? 222.176 230.032 221.260 1.00 64.79  ? 240 ASP   A OD1   1 
ATOM   2055 O OD2   . ASP   C 2 228 ? 223.065 232.015 220.964 1.00 70.90  ? 240 ASP   A OD2   1 
ATOM   2056 N N     . GLN   C 2 229 ? 223.139 229.687 225.640 1.00 53.10  ? 241 GLN   A N     1 
ATOM   2057 C CA    . GLN   C 2 229 ? 224.042 228.761 226.318 1.00 51.94  ? 241 GLN   A CA    1 
ATOM   2058 C C     . GLN   C 2 229 ? 223.331 227.462 226.671 1.00 49.20  ? 241 GLN   A C     1 
ATOM   2059 O O     . GLN   C 2 229 ? 223.906 226.374 226.547 1.00 47.97  ? 241 GLN   A O     1 
ATOM   2060 C CB    . GLN   C 2 229 ? 224.610 229.412 227.578 1.00 53.33  ? 241 GLN   A CB    1 
ATOM   2061 C CG    . GLN   C 2 229 ? 225.836 230.269 227.342 1.00 62.97  ? 241 GLN   A CG    1 
ATOM   2062 C CD    . GLN   C 2 229 ? 226.214 231.081 228.564 1.00 72.49  ? 241 GLN   A CD    1 
ATOM   2063 O OE1   . GLN   C 2 229 ? 225.846 230.739 229.686 1.00 69.13  ? 241 GLN   A OE1   1 
ATOM   2064 N NE2   . GLN   C 2 229 ? 226.953 232.163 228.351 1.00 78.74  ? 241 GLN   A NE2   1 
ATOM   2065 N N     . VAL   C 2 230 ? 222.083 227.562 227.129 1.00 50.98  ? 242 VAL   A N     1 
ATOM   2066 C CA    . VAL   C 2 230 ? 221.305 226.371 227.460 1.00 50.09  ? 242 VAL   A CA    1 
ATOM   2067 C C     . VAL   C 2 230 ? 221.083 225.516 226.220 1.00 50.03  ? 242 VAL   A C     1 
ATOM   2068 O O     . VAL   C 2 230 ? 221.181 224.284 226.269 1.00 53.29  ? 242 VAL   A O     1 
ATOM   2069 C CB    . VAL   C 2 230 ? 219.974 226.774 228.119 1.00 48.22  ? 242 VAL   A CB    1 
ATOM   2070 C CG1   . VAL   C 2 230 ? 219.048 225.576 228.230 1.00 48.10  ? 242 VAL   A CG1   1 
ATOM   2071 C CG2   . VAL   C 2 230 ? 220.227 227.379 229.488 1.00 48.13  ? 242 VAL   A CG2   1 
ATOM   2072 N N     . ARG   C 2 231 ? 220.783 226.154 225.088 1.00 50.90  ? 243 ARG   A N     1 
ATOM   2073 C CA    . ARG   C 2 231 ? 220.502 225.402 223.870 1.00 52.11  ? 243 ARG   A CA    1 
ATOM   2074 C C     . ARG   C 2 231 ? 221.730 224.652 223.360 1.00 55.73  ? 243 ARG   A C     1 
ATOM   2075 O O     . ARG   C 2 231 ? 221.592 223.590 222.743 1.00 55.64  ? 243 ARG   A O     1 
ATOM   2076 C CB    . ARG   C 2 231 ? 219.974 226.346 222.792 1.00 53.91  ? 243 ARG   A CB    1 
ATOM   2077 C CG    . ARG   C 2 231 ? 219.681 225.683 221.468 1.00 53.17  ? 243 ARG   A CG    1 
ATOM   2078 C CD    . ARG   C 2 231 ? 220.464 226.330 220.352 1.00 50.16  ? 243 ARG   A CD    1 
ATOM   2079 N NE    . ARG   C 2 231 ? 219.897 227.615 219.972 1.00 48.50  ? 243 ARG   A NE    1 
ATOM   2080 C CZ    . ARG   C 2 231 ? 220.549 228.543 219.288 1.00 54.33  ? 243 ARG   A CZ    1 
ATOM   2081 N NH1   . ARG   C 2 231 ? 221.799 228.362 218.896 1.00 57.70  ? 243 ARG   A NH1   1 
ATOM   2082 N NH2   . ARG   C 2 231 ? 219.934 229.685 218.994 1.00 57.65  ? 243 ARG   A NH2   1 
ATOM   2083 N N     . GLU   C 2 232 ? 222.931 225.171 223.623 1.00 57.71  ? 244 GLU   A N     1 
ATOM   2084 C CA    . GLU   C 2 232 ? 224.133 224.615 223.008 1.00 54.98  ? 244 GLU   A CA    1 
ATOM   2085 C C     . GLU   C 2 232 ? 224.477 223.227 223.536 1.00 56.35  ? 244 GLU   A C     1 
ATOM   2086 O O     . GLU   C 2 232 ? 225.086 222.432 222.813 1.00 57.90  ? 244 GLU   A O     1 
ATOM   2087 C CB    . GLU   C 2 232 ? 225.313 225.563 223.215 1.00 53.05  ? 244 GLU   A CB    1 
ATOM   2088 C CG    . GLU   C 2 232 ? 225.347 226.736 222.250 1.00 61.89  ? 244 GLU   A CG    1 
ATOM   2089 C CD    . GLU   C 2 232 ? 224.868 226.368 220.857 1.00 75.31  ? 244 GLU   A CD    1 
ATOM   2090 O OE1   . GLU   C 2 232 ? 225.428 225.424 220.260 1.00 78.47  ? 244 GLU   A OE1   1 
ATOM   2091 O OE2   . GLU   C 2 232 ? 223.931 227.024 220.358 1.00 76.47  ? 244 GLU   A OE2   1 
ATOM   2092 N N     . SER   C 2 233 ? 224.115 222.918 224.780 1.00 53.56  ? 245 SER   A N     1 
ATOM   2093 C CA    . SER   C 2 233 ? 224.470 221.627 225.356 1.00 53.01  ? 245 SER   A CA    1 
ATOM   2094 C C     . SER   C 2 233 ? 223.783 220.493 224.605 1.00 56.74  ? 245 SER   A C     1 
ATOM   2095 O O     . SER   C 2 233 ? 222.571 220.527 224.378 1.00 57.90  ? 245 SER   A O     1 
ATOM   2096 C CB    . SER   C 2 233 ? 224.091 221.593 226.834 1.00 55.46  ? 245 SER   A CB    1 
ATOM   2097 O OG    . SER   C 2 233 ? 222.690 221.464 226.989 1.00 61.26  ? 245 SER   A OG    1 
ATOM   2098 N N     . ARG   C 2 234 ? 224.566 219.479 224.226 1.00 54.46  ? 246 ARG   A N     1 
ATOM   2099 C CA    . ARG   C 2 234 ? 224.044 218.427 223.358 1.00 61.02  ? 246 ARG   A CA    1 
ATOM   2100 C C     . ARG   C 2 234 ? 223.117 217.480 224.111 1.00 60.97  ? 246 ARG   A C     1 
ATOM   2101 O O     . ARG   C 2 234 ? 222.060 217.100 223.595 1.00 62.07  ? 246 ARG   A O     1 
ATOM   2102 C CB    . ARG   C 2 234 ? 225.195 217.656 222.715 1.00 66.37  ? 246 ARG   A CB    1 
ATOM   2103 C CG    . ARG   C 2 234 ? 226.036 218.476 221.743 1.00 69.84  ? 246 ARG   A CG    1 
ATOM   2104 C CD    . ARG   C 2 234 ? 225.189 219.390 220.857 1.00 66.17  ? 246 ARG   A CD    1 
ATOM   2105 N NE    . ARG   C 2 234 ? 224.108 218.698 220.164 1.00 62.13  ? 246 ARG   A NE    1 
ATOM   2106 C CZ    . ARG   C 2 234 ? 224.274 217.751 219.250 1.00 62.05  ? 246 ARG   A CZ    1 
ATOM   2107 N NH1   . ARG   C 2 234 ? 225.478 217.371 218.857 1.00 66.54  ? 246 ARG   A NH1   1 
ATOM   2108 N NH2   . ARG   C 2 234 ? 223.204 217.181 218.706 1.00 64.90  ? 246 ARG   A NH2   1 
ATOM   2109 N N     . ASN   C 2 235 ? 223.491 217.085 225.325 1.00 58.45  ? 247 ASN   A N     1 
ATOM   2110 C CA    . ASN   C 2 235 ? 222.659 216.236 226.177 1.00 55.71  ? 247 ASN   A CA    1 
ATOM   2111 C C     . ASN   C 2 235 ? 222.466 216.966 227.498 1.00 55.95  ? 247 ASN   A C     1 
ATOM   2112 O O     . ASN   C 2 235 ? 223.162 216.695 228.485 1.00 57.85  ? 247 ASN   A O     1 
ATOM   2113 C CB    . ASN   C 2 235 ? 223.275 214.851 226.373 1.00 54.17  ? 247 ASN   A CB    1 
ATOM   2114 C CG    . ASN   C 2 235 ? 224.739 214.910 226.749 1.00 68.19  ? 247 ASN   A CG    1 
ATOM   2115 O OD1   . ASN   C 2 235 ? 225.408 215.917 226.523 1.00 71.91  ? 247 ASN   A OD1   1 
ATOM   2116 N ND2   . ASN   C 2 235 ? 225.244 213.829 227.332 1.00 69.63  ? 247 ASN   A ND2   1 
ATOM   2117 N N     . PRO   C 2 236 ? 221.532 217.910 227.545 1.00 54.60  ? 248 PRO   A N     1 
ATOM   2118 C CA    . PRO   C 2 236 ? 221.382 218.744 228.739 1.00 53.80  ? 248 PRO   A CA    1 
ATOM   2119 C C     . PRO   C 2 236 ? 220.905 217.948 229.942 1.00 49.50  ? 248 PRO   A C     1 
ATOM   2120 O O     . PRO   C 2 236 ? 220.174 216.963 229.818 1.00 46.71  ? 248 PRO   A O     1 
ATOM   2121 C CB    . PRO   C 2 236 ? 220.341 219.781 228.309 1.00 56.44  ? 248 PRO   A CB    1 
ATOM   2122 C CG    . PRO   C 2 236 ? 219.556 219.090 227.247 1.00 54.10  ? 248 PRO   A CG    1 
ATOM   2123 C CD    . PRO   C 2 236 ? 220.544 218.246 226.507 1.00 53.84  ? 248 PRO   A CD    1 
ATOM   2124 N N     . GLY   C 2 237 ? 221.325 218.399 231.121 1.00 45.90  ? 249 GLY   A N     1 
ATOM   2125 C CA    . GLY   C 2 237 ? 221.042 217.719 232.370 1.00 43.72  ? 249 GLY   A CA    1 
ATOM   2126 C C     . GLY   C 2 237 ? 220.461 218.671 233.399 1.00 46.21  ? 249 GLY   A C     1 
ATOM   2127 O O     . GLY   C 2 237 ? 219.648 219.540 233.092 1.00 48.94  ? 249 GLY   A O     1 
ATOM   2128 N N     . ASN   C 2 238 ? 220.899 218.491 234.647 1.00 46.93  ? 250 ASN   A N     1 
ATOM   2129 C CA    . ASN   C 2 238 ? 220.326 219.255 235.752 1.00 47.34  ? 250 ASN   A CA    1 
ATOM   2130 C C     . ASN   C 2 238 ? 220.775 220.710 235.722 1.00 47.65  ? 250 ASN   A C     1 
ATOM   2131 O O     . ASN   C 2 238 ? 220.033 221.601 236.148 1.00 51.34  ? 250 ASN   A O     1 
ATOM   2132 C CB    . ASN   C 2 238 ? 220.698 218.605 237.083 1.00 51.18  ? 250 ASN   A CB    1 
ATOM   2133 C CG    . ASN   C 2 238 ? 220.161 219.372 238.274 1.00 59.65  ? 250 ASN   A CG    1 
ATOM   2134 O OD1   . ASN   C 2 238 ? 219.055 219.909 238.234 1.00 63.37  ? 250 ASN   A OD1   1 
ATOM   2135 N ND2   . ASN   C 2 238 ? 220.945 219.428 239.343 1.00 61.29  ? 250 ASN   A ND2   1 
ATOM   2136 N N     . ALA   C 2 239 ? 221.991 220.971 235.237 1.00 47.78  ? 251 ALA   A N     1 
ATOM   2137 C CA    . ALA   C 2 239 ? 222.476 222.346 235.167 1.00 47.63  ? 251 ALA   A CA    1 
ATOM   2138 C C     . ALA   C 2 239 ? 221.628 223.185 234.221 1.00 45.81  ? 251 ALA   A C     1 
ATOM   2139 O O     . ALA   C 2 239 ? 221.281 224.331 234.534 1.00 44.18  ? 251 ALA   A O     1 
ATOM   2140 C CB    . ALA   C 2 239 ? 223.941 222.363 234.736 1.00 49.35  ? 251 ALA   A CB    1 
ATOM   2141 N N     . GLU   C 2 240 ? 221.282 222.630 233.057 1.00 47.74  ? 252 GLU   A N     1 
ATOM   2142 C CA    . GLU   C 2 240 ? 220.434 223.351 232.114 1.00 49.33  ? 252 GLU   A CA    1 
ATOM   2143 C C     . GLU   C 2 240 ? 219.039 223.567 232.684 1.00 48.52  ? 252 GLU   A C     1 
ATOM   2144 O O     . GLU   C 2 240 ? 218.433 224.623 232.474 1.00 47.85  ? 252 GLU   A O     1 
ATOM   2145 C CB    . GLU   C 2 240 ? 220.358 222.598 230.786 1.00 50.05  ? 252 GLU   A CB    1 
ATOM   2146 C CG    . GLU   C 2 240 ? 221.569 222.769 229.882 1.00 51.76  ? 252 GLU   A CG    1 
ATOM   2147 C CD    . GLU   C 2 240 ? 222.863 222.338 230.538 1.00 60.34  ? 252 GLU   A CD    1 
ATOM   2148 O OE1   . GLU   C 2 240 ? 223.029 221.126 230.786 1.00 59.66  ? 252 GLU   A OE1   1 
ATOM   2149 O OE2   . GLU   C 2 240 ? 223.714 223.212 230.808 1.00 67.47  ? 252 GLU   A OE2   1 
ATOM   2150 N N     . PHE   C 2 241 ? 218.511 222.573 233.397 1.00 46.66  ? 253 PHE   A N     1 
ATOM   2151 C CA    . PHE   C 2 241 ? 217.206 222.719 234.033 1.00 44.35  ? 253 PHE   A CA    1 
ATOM   2152 C C     . PHE   C 2 241 ? 217.228 223.828 235.080 1.00 44.44  ? 253 PHE   A C     1 
ATOM   2153 O O     . PHE   C 2 241 ? 216.288 224.627 235.172 1.00 45.52  ? 253 PHE   A O     1 
ATOM   2154 C CB    . PHE   C 2 241 ? 216.788 221.378 234.641 1.00 45.37  ? 253 PHE   A CB    1 
ATOM   2155 C CG    . PHE   C 2 241 ? 215.791 221.486 235.755 1.00 48.74  ? 253 PHE   A CG    1 
ATOM   2156 C CD1   . PHE   C 2 241 ? 214.457 221.725 235.488 1.00 54.72  ? 253 PHE   A CD1   1 
ATOM   2157 C CD2   . PHE   C 2 241 ? 216.185 221.318 237.070 1.00 51.23  ? 253 PHE   A CD2   1 
ATOM   2158 C CE1   . PHE   C 2 241 ? 213.538 221.813 236.512 1.00 58.03  ? 253 PHE   A CE1   1 
ATOM   2159 C CE2   . PHE   C 2 241 ? 215.271 221.405 238.097 1.00 52.37  ? 253 PHE   A CE2   1 
ATOM   2160 C CZ    . PHE   C 2 241 ? 213.947 221.653 237.818 1.00 54.16  ? 253 PHE   A CZ    1 
ATOM   2161 N N     . GLU   C 2 242 ? 218.305 223.903 235.864 1.00 45.51  ? 254 GLU   A N     1 
ATOM   2162 C CA    . GLU   C 2 242 ? 218.445 224.972 236.848 1.00 44.03  ? 254 GLU   A CA    1 
ATOM   2163 C C     . GLU   C 2 242 ? 218.555 226.334 236.173 1.00 44.83  ? 254 GLU   A C     1 
ATOM   2164 O O     . GLU   C 2 242 ? 217.981 227.322 236.648 1.00 44.01  ? 254 GLU   A O     1 
ATOM   2165 C CB    . GLU   C 2 242 ? 219.665 224.701 237.724 1.00 47.27  ? 254 GLU   A CB    1 
ATOM   2166 C CG    . GLU   C 2 242 ? 219.418 224.853 239.207 1.00 54.75  ? 254 GLU   A CG    1 
ATOM   2167 C CD    . GLU   C 2 242 ? 220.444 224.110 240.034 1.00 62.09  ? 254 GLU   A CD    1 
ATOM   2168 O OE1   . GLU   C 2 242 ? 221.648 224.415 239.901 1.00 65.84  ? 254 GLU   A OE1   1 
ATOM   2169 O OE2   . GLU   C 2 242 ? 220.050 223.218 240.811 1.00 62.90  ? 254 GLU   A OE2   1 
ATOM   2170 N N     . ASP   C 2 243 ? 219.301 226.407 235.067 1.00 47.91  ? 255 ASP   A N     1 
ATOM   2171 C CA    . ASP   C 2 243 ? 219.403 227.659 234.322 1.00 48.34  ? 255 ASP   A CA    1 
ATOM   2172 C C     . ASP   C 2 243 ? 218.050 228.085 233.767 1.00 45.52  ? 255 ASP   A C     1 
ATOM   2173 O O     . ASP   C 2 243 ? 217.716 229.273 233.779 1.00 47.53  ? 255 ASP   A O     1 
ATOM   2174 C CB    . ASP   C 2 243 ? 220.426 227.523 233.195 1.00 52.60  ? 255 ASP   A CB    1 
ATOM   2175 C CG    . ASP   C 2 243 ? 221.854 227.609 233.691 1.00 59.43  ? 255 ASP   A CG    1 
ATOM   2176 O OD1   . ASP   C 2 243 ? 222.060 228.063 234.835 1.00 62.80  ? 255 ASP   A OD1   1 
ATOM   2177 O OD2   . ASP   C 2 243 ? 222.771 227.228 232.938 1.00 61.48  ? 255 ASP   A OD2   1 
ATOM   2178 N N     . LEU   C 2 244 ? 217.260 227.131 233.270 1.00 43.54  ? 256 LEU   A N     1 
ATOM   2179 C CA    . LEU   C 2 244 ? 215.920 227.453 232.787 1.00 43.37  ? 256 LEU   A CA    1 
ATOM   2180 C C     . LEU   C 2 244 ? 215.022 227.931 233.922 1.00 46.54  ? 256 LEU   A C     1 
ATOM   2181 O O     . LEU   C 2 244 ? 214.214 228.849 233.738 1.00 47.54  ? 256 LEU   A O     1 
ATOM   2182 C CB    . LEU   C 2 244 ? 215.303 226.241 232.093 1.00 45.83  ? 256 LEU   A CB    1 
ATOM   2183 C CG    . LEU   C 2 244 ? 215.889 225.861 230.735 1.00 48.68  ? 256 LEU   A CG    1 
ATOM   2184 C CD1   . LEU   C 2 244 ? 215.355 224.513 230.291 1.00 48.98  ? 256 LEU   A CD1   1 
ATOM   2185 C CD2   . LEU   C 2 244 ? 215.574 226.929 229.706 1.00 47.47  ? 256 LEU   A CD2   1 
ATOM   2186 N N     . ILE   C 2 245 ? 215.140 227.311 235.097 1.00 47.47  ? 257 ILE   A N     1 
ATOM   2187 C CA    . ILE   C 2 245 ? 214.387 227.769 236.262 1.00 44.54  ? 257 ILE   A CA    1 
ATOM   2188 C C     . ILE   C 2 245 ? 214.748 229.213 236.585 1.00 41.50  ? 257 ILE   A C     1 
ATOM   2189 O O     . ILE   C 2 245 ? 213.877 230.055 236.837 1.00 40.83  ? 257 ILE   A O     1 
ATOM   2190 C CB    . ILE   C 2 245 ? 214.645 226.843 237.464 1.00 44.31  ? 257 ILE   A CB    1 
ATOM   2191 C CG1   . ILE   C 2 245 ? 213.935 225.505 237.274 1.00 43.37  ? 257 ILE   A CG1   1 
ATOM   2192 C CG2   . ILE   C 2 245 ? 214.186 227.498 238.756 1.00 46.39  ? 257 ILE   A CG2   1 
ATOM   2193 C CD1   . ILE   C 2 245 ? 212.440 225.614 237.287 1.00 46.22  ? 257 ILE   A CD1   1 
ATOM   2194 N N     . PHE   C 2 246 ? 216.046 229.521 236.570 1.00 41.16  ? 258 PHE   A N     1 
ATOM   2195 C CA    . PHE   C 2 246 ? 216.491 230.882 236.853 1.00 43.60  ? 258 PHE   A CA    1 
ATOM   2196 C C     . PHE   C 2 246 ? 215.994 231.858 235.792 1.00 44.12  ? 258 PHE   A C     1 
ATOM   2197 O O     . PHE   C 2 246 ? 215.638 233.000 236.103 1.00 43.54  ? 258 PHE   A O     1 
ATOM   2198 C CB    . PHE   C 2 246 ? 218.014 230.920 236.948 1.00 45.34  ? 258 PHE   A CB    1 
ATOM   2199 C CG    . PHE   C 2 246 ? 218.573 232.295 237.135 1.00 43.35  ? 258 PHE   A CG    1 
ATOM   2200 C CD1   . PHE   C 2 246 ? 218.260 233.036 238.258 1.00 44.03  ? 258 PHE   A CD1   1 
ATOM   2201 C CD2   . PHE   C 2 246 ? 219.409 232.848 236.187 1.00 43.47  ? 258 PHE   A CD2   1 
ATOM   2202 C CE1   . PHE   C 2 246 ? 218.776 234.301 238.430 1.00 46.82  ? 258 PHE   A CE1   1 
ATOM   2203 C CE2   . PHE   C 2 246 ? 219.925 234.114 236.354 1.00 44.45  ? 258 PHE   A CE2   1 
ATOM   2204 C CZ    . PHE   C 2 246 ? 219.608 234.841 237.478 1.00 46.02  ? 258 PHE   A CZ    1 
ATOM   2205 N N     . LEU   C 2 247 ? 215.977 231.425 234.531 1.00 44.51  ? 259 LEU   A N     1 
ATOM   2206 C CA    . LEU   C 2 247 ? 215.478 232.269 233.452 1.00 41.50  ? 259 LEU   A CA    1 
ATOM   2207 C C     . LEU   C 2 247 ? 214.001 232.582 233.644 1.00 41.66  ? 259 LEU   A C     1 
ATOM   2208 O O     . LEU   C 2 247 ? 213.563 233.722 233.457 1.00 40.13  ? 259 LEU   A O     1 
ATOM   2209 C CB    . LEU   C 2 247 ? 215.710 231.579 232.110 1.00 41.34  ? 259 LEU   A CB    1 
ATOM   2210 C CG    . LEU   C 2 247 ? 216.797 232.166 231.218 1.00 42.34  ? 259 LEU   A CG    1 
ATOM   2211 C CD1   . LEU   C 2 247 ? 216.724 231.553 229.834 1.00 45.60  ? 259 LEU   A CD1   1 
ATOM   2212 C CD2   . LEU   C 2 247 ? 216.666 233.671 231.153 1.00 44.73  ? 259 LEU   A CD2   1 
ATOM   2213 N N     . ALA   C 2 248 ? 213.215 231.569 234.012 1.00 42.62  ? 260 ALA   A N     1 
ATOM   2214 C CA    . ALA   C 2 248 ? 211.798 231.788 234.270 1.00 40.97  ? 260 ALA   A CA    1 
ATOM   2215 C C     . ALA   C 2 248 ? 211.595 232.718 235.457 1.00 41.88  ? 260 ALA   A C     1 
ATOM   2216 O O     . ALA   C 2 248 ? 210.719 233.590 235.431 1.00 43.31  ? 260 ALA   A O     1 
ATOM   2217 C CB    . ALA   C 2 248 ? 211.094 230.453 234.503 1.00 41.56  ? 260 ALA   A CB    1 
ATOM   2218 N N     . ARG   C 2 249 ? 212.397 232.548 236.509 1.00 43.44  ? 261 ARG   A N     1 
ATOM   2219 C CA    . ARG   C 2 249 ? 212.277 233.414 237.676 1.00 43.99  ? 261 ARG   A CA    1 
ATOM   2220 C C     . ARG   C 2 249 ? 212.629 234.856 237.329 1.00 41.92  ? 261 ARG   A C     1 
ATOM   2221 O O     . ARG   C 2 249 ? 212.012 235.796 237.843 1.00 41.21  ? 261 ARG   A O     1 
ATOM   2222 C CB    . ARG   C 2 249 ? 213.168 232.898 238.804 1.00 43.06  ? 261 ARG   A CB    1 
ATOM   2223 C CG    . ARG   C 2 249 ? 213.072 233.706 240.080 1.00 46.02  ? 261 ARG   A CG    1 
ATOM   2224 C CD    . ARG   C 2 249 ? 213.732 232.988 241.241 1.00 47.03  ? 261 ARG   A CD    1 
ATOM   2225 N NE    . ARG   C 2 249 ? 212.999 231.794 241.645 1.00 47.04  ? 261 ARG   A NE    1 
ATOM   2226 C CZ    . ARG   C 2 249 ? 213.506 230.570 241.641 1.00 46.41  ? 261 ARG   A CZ    1 
ATOM   2227 N NH1   . ARG   C 2 249 ? 214.751 230.341 241.259 1.00 43.63  ? 261 ARG   A NH1   1 
ATOM   2228 N NH2   . ARG   C 2 249 ? 212.748 229.552 242.032 1.00 47.11  ? 261 ARG   A NH2   1 
ATOM   2229 N N     . SER   C 2 250 ? 213.623 235.050 236.460 1.00 43.02  ? 262 SER   A N     1 
ATOM   2230 C CA    . SER   C 2 250 ? 214.006 236.394 236.046 1.00 44.51  ? 262 SER   A CA    1 
ATOM   2231 C C     . SER   C 2 250 ? 212.954 237.053 235.165 1.00 43.94  ? 262 SER   A C     1 
ATOM   2232 O O     . SER   C 2 250 ? 212.956 238.281 235.037 1.00 45.76  ? 262 SER   A O     1 
ATOM   2233 C CB    . SER   C 2 250 ? 215.345 236.357 235.311 1.00 46.62  ? 262 SER   A CB    1 
ATOM   2234 O OG    . SER   C 2 250 ? 215.240 235.630 234.101 1.00 48.41  ? 262 SER   A OG    1 
ATOM   2235 N N     . ALA   C 2 251 ? 212.064 236.270 234.554 1.00 43.54  ? 263 ALA   A N     1 
ATOM   2236 C CA    . ALA   C 2 251 ? 211.018 236.829 233.707 1.00 43.06  ? 263 ALA   A CA    1 
ATOM   2237 C C     . ALA   C 2 251 ? 209.942 237.556 234.498 1.00 42.01  ? 263 ALA   A C     1 
ATOM   2238 O O     . ALA   C 2 251 ? 209.136 238.274 233.898 1.00 42.35  ? 263 ALA   A O     1 
ATOM   2239 C CB    . ALA   C 2 251 ? 210.378 235.726 232.864 1.00 45.70  ? 263 ALA   A CB    1 
ATOM   2240 N N     . LEU   C 2 252 ? 209.901 237.384 235.820 1.00 42.20  ? 264 LEU   A N     1 
ATOM   2241 C CA    . LEU   C 2 252 ? 208.922 238.093 236.632 1.00 42.08  ? 264 LEU   A CA    1 
ATOM   2242 C C     . LEU   C 2 252 ? 209.258 239.573 236.772 1.00 42.48  ? 264 LEU   A C     1 
ATOM   2243 O O     . LEU   C 2 252 ? 208.346 240.390 236.931 1.00 40.68  ? 264 LEU   A O     1 
ATOM   2244 C CB    . LEU   C 2 252 ? 208.823 237.443 238.010 1.00 39.63  ? 264 LEU   A CB    1 
ATOM   2245 C CG    . LEU   C 2 252 ? 208.376 235.980 238.039 1.00 36.81  ? 264 LEU   A CG    1 
ATOM   2246 C CD1   . LEU   C 2 252 ? 208.754 235.324 239.354 1.00 37.67  ? 264 LEU   A CD1   1 
ATOM   2247 C CD2   . LEU   C 2 252 ? 206.886 235.858 237.796 1.00 37.31  ? 264 LEU   A CD2   1 
ATOM   2248 N N     . ILE   C 2 253 ? 210.539 239.931 236.720 1.00 43.65  ? 265 ILE   A N     1 
ATOM   2249 C CA    . ILE   C 2 253 ? 210.981 241.324 236.773 1.00 44.87  ? 265 ILE   A CA    1 
ATOM   2250 C C     . ILE   C 2 253 ? 211.393 241.818 235.392 1.00 45.72  ? 265 ILE   A C     1 
ATOM   2251 O O     . ILE   C 2 253 ? 210.937 242.868 234.936 1.00 47.05  ? 265 ILE   A O     1 
ATOM   2252 C CB    . ILE   C 2 253 ? 212.123 241.509 237.795 1.00 42.47  ? 265 ILE   A CB    1 
ATOM   2253 C CG1   . ILE   C 2 253 ? 211.740 240.916 239.149 1.00 42.45  ? 265 ILE   A CG1   1 
ATOM   2254 C CG2   . ILE   C 2 253 ? 212.472 242.974 237.940 1.00 41.14  ? 265 ILE   A CG2   1 
ATOM   2255 C CD1   . ILE   C 2 253 ? 212.863 240.949 240.150 1.00 44.28  ? 265 ILE   A CD1   1 
ATOM   2256 N N     . LEU   C 2 254 ? 212.267 241.077 234.713 1.00 44.57  ? 266 LEU   A N     1 
ATOM   2257 C CA    . LEU   C 2 254 ? 212.634 241.368 233.329 1.00 43.90  ? 266 LEU   A CA    1 
ATOM   2258 C C     . LEU   C 2 254 ? 211.641 240.639 232.428 1.00 46.99  ? 266 LEU   A C     1 
ATOM   2259 O O     . LEU   C 2 254 ? 211.889 239.543 231.921 1.00 51.70  ? 266 LEU   A O     1 
ATOM   2260 C CB    . LEU   C 2 254 ? 214.071 240.951 233.055 1.00 43.99  ? 266 LEU   A CB    1 
ATOM   2261 C CG    . LEU   C 2 254 ? 215.095 241.441 234.076 1.00 42.94  ? 266 LEU   A CG    1 
ATOM   2262 C CD1   . LEU   C 2 254 ? 216.497 241.035 233.667 1.00 47.50  ? 266 LEU   A CD1   1 
ATOM   2263 C CD2   . LEU   C 2 254 ? 215.000 242.946 234.230 1.00 40.77  ? 266 LEU   A CD2   1 
ATOM   2264 N N     . ARG   C 2 255 ? 210.487 241.272 232.239 1.00 44.16  ? 267 ARG   A N     1 
ATOM   2265 C CA    . ARG   C 2 255 ? 209.372 240.631 231.558 1.00 44.91  ? 267 ARG   A CA    1 
ATOM   2266 C C     . ARG   C 2 255 ? 209.709 240.320 230.105 1.00 45.72  ? 267 ARG   A C     1 
ATOM   2267 O O     . ARG   C 2 255 ? 210.448 241.056 229.448 1.00 48.66  ? 267 ARG   A O     1 
ATOM   2268 C CB    . ARG   C 2 255 ? 208.138 241.525 231.631 1.00 44.80  ? 267 ARG   A CB    1 
ATOM   2269 C CG    . ARG   C 2 255 ? 207.261 241.256 232.832 1.00 41.02  ? 267 ARG   A CG    1 
ATOM   2270 C CD    . ARG   C 2 255 ? 206.303 242.401 233.070 1.00 40.60  ? 267 ARG   A CD    1 
ATOM   2271 N NE    . ARG   C 2 255 ? 206.787 243.306 234.104 1.00 41.23  ? 267 ARG   A NE    1 
ATOM   2272 C CZ    . ARG   C 2 255 ? 206.549 243.153 235.399 1.00 41.74  ? 267 ARG   A CZ    1 
ATOM   2273 N NH1   . ARG   C 2 255 ? 205.842 242.135 235.856 1.00 43.81  ? 267 ARG   A NH1   1 
ATOM   2274 N NH2   . ARG   C 2 255 ? 207.033 244.045 236.257 1.00 41.30  ? 267 ARG   A NH2   1 
ATOM   2275 N N     . GLY   C 2 256 ? 209.166 239.207 229.612 1.00 43.85  ? 268 GLY   A N     1 
ATOM   2276 C CA    . GLY   C 2 256 ? 209.321 238.845 228.222 1.00 46.27  ? 268 GLY   A CA    1 
ATOM   2277 C C     . GLY   C 2 256 ? 208.167 239.328 227.362 1.00 49.00  ? 268 GLY   A C     1 
ATOM   2278 O O     . GLY   C 2 256 ? 207.078 239.619 227.849 1.00 54.77  ? 268 GLY   A O     1 
ATOM   2279 N N     . SER   C 2 257 ? 208.421 239.407 226.059 1.00 48.40  ? 269 SER   A N     1 
ATOM   2280 C CA    . SER   C 2 257 ? 207.432 239.915 225.115 1.00 47.79  ? 269 SER   A CA    1 
ATOM   2281 C C     . SER   C 2 257 ? 206.490 238.783 224.727 1.00 46.53  ? 269 SER   A C     1 
ATOM   2282 O O     . SER   C 2 257 ? 206.888 237.844 224.031 1.00 50.34  ? 269 SER   A O     1 
ATOM   2283 C CB    . SER   C 2 257 ? 208.121 240.503 223.888 1.00 45.73  ? 269 SER   A CB    1 
ATOM   2284 O OG    . SER   C 2 257 ? 208.744 239.492 223.119 1.00 47.95  ? 269 SER   A OG    1 
ATOM   2285 N N     . VAL   C 2 258 ? 205.239 238.871 225.168 1.00 44.67  ? 270 VAL   A N     1 
ATOM   2286 C CA    . VAL   C 2 258 ? 204.226 237.861 224.892 1.00 45.63  ? 270 VAL   A CA    1 
ATOM   2287 C C     . VAL   C 2 258 ? 203.059 238.534 224.185 1.00 47.22  ? 270 VAL   A C     1 
ATOM   2288 O O     . VAL   C 2 258 ? 202.523 239.532 224.677 1.00 49.51  ? 270 VAL   A O     1 
ATOM   2289 C CB    . VAL   C 2 258 ? 203.761 237.160 226.180 1.00 47.74  ? 270 VAL   A CB    1 
ATOM   2290 C CG1   . VAL   C 2 258 ? 202.524 236.326 225.912 1.00 51.31  ? 270 VAL   A CG1   1 
ATOM   2291 C CG2   . VAL   C 2 258 ? 204.876 236.297 226.739 1.00 44.86  ? 270 VAL   A CG2   1 
ATOM   2292 N N     . ALA   C 2 259 ? 202.671 237.989 223.036 1.00 46.81  ? 271 ALA   A N     1 
ATOM   2293 C CA    . ALA   C 2 259 ? 201.590 238.574 222.257 1.00 47.25  ? 271 ALA   A CA    1 
ATOM   2294 C C     . ALA   C 2 259 ? 200.248 238.337 222.933 1.00 48.23  ? 271 ALA   A C     1 
ATOM   2295 O O     . ALA   C 2 259 ? 199.998 237.271 223.500 1.00 51.05  ? 271 ALA   A O     1 
ATOM   2296 C CB    . ALA   C 2 259 ? 201.577 237.993 220.845 1.00 43.57  ? 271 ALA   A CB    1 
ATOM   2297 N N     . HIS   C 2 260 ? 199.379 239.342 222.870 1.00 46.24  ? 272 HIS   A N     1 
ATOM   2298 C CA    . HIS   C 2 260 ? 198.032 239.248 223.412 1.00 44.22  ? 272 HIS   A CA    1 
ATOM   2299 C C     . HIS   C 2 260 ? 197.035 239.587 222.316 1.00 47.03  ? 272 HIS   A C     1 
ATOM   2300 O O     . HIS   C 2 260 ? 197.117 240.659 221.709 1.00 52.86  ? 272 HIS   A O     1 
ATOM   2301 C CB    . HIS   C 2 260 ? 197.846 240.188 224.605 1.00 43.57  ? 272 HIS   A CB    1 
ATOM   2302 C CG    . HIS   C 2 260 ? 198.756 239.893 225.755 1.00 46.92  ? 272 HIS   A CG    1 
ATOM   2303 N ND1   . HIS   C 2 260 ? 199.989 240.490 225.900 1.00 49.28  ? 272 HIS   A ND1   1 
ATOM   2304 C CD2   . HIS   C 2 260 ? 198.612 239.066 226.817 1.00 47.11  ? 272 HIS   A CD2   1 
ATOM   2305 C CE1   . HIS   C 2 260 ? 200.565 240.044 227.001 1.00 48.27  ? 272 HIS   A CE1   1 
ATOM   2306 N NE2   . HIS   C 2 260 ? 199.750 239.180 227.576 1.00 44.82  ? 272 HIS   A NE2   1 
ATOM   2307 N N     . LYS   C 2 261 ? 196.096 238.680 222.069 1.00 43.31  ? 273 LYS   A N     1 
ATOM   2308 C CA    . LYS   C 2 261 ? 195.089 238.857 221.034 1.00 42.83  ? 273 LYS   A CA    1 
ATOM   2309 C C     . LYS   C 2 261 ? 193.706 238.618 221.618 1.00 44.58  ? 273 LYS   A C     1 
ATOM   2310 O O     . LYS   C 2 261 ? 193.531 237.804 222.528 1.00 49.76  ? 273 LYS   A O     1 
ATOM   2311 C CB    . LYS   C 2 261 ? 195.320 237.906 219.852 1.00 43.27  ? 273 LYS   A CB    1 
ATOM   2312 C CG    . LYS   C 2 261 ? 196.712 237.971 219.253 1.00 39.87  ? 273 LYS   A CG    1 
ATOM   2313 C CD    . LYS   C 2 261 ? 197.016 236.723 218.445 1.00 39.34  ? 273 LYS   A CD    1 
ATOM   2314 C CE    . LYS   C 2 261 ? 198.319 236.860 217.687 1.00 36.86  ? 273 LYS   A CE    1 
ATOM   2315 N NZ    . LYS   C 2 261 ? 198.626 238.279 217.375 1.00 41.33  ? 273 LYS   A NZ    1 
ATOM   2316 N N     . SER   C 2 262 ? 192.722 239.338 221.082 1.00 41.99  ? 274 SER   A N     1 
ATOM   2317 C CA    . SER   C 2 262 ? 191.330 239.202 221.510 1.00 42.04  ? 274 SER   A CA    1 
ATOM   2318 C C     . SER   C 2 262 ? 190.644 238.194 220.600 1.00 43.98  ? 274 SER   A C     1 
ATOM   2319 O O     . SER   C 2 262 ? 190.095 238.539 219.554 1.00 44.96  ? 274 SER   A O     1 
ATOM   2320 C CB    . SER   C 2 262 ? 190.617 240.547 221.481 1.00 43.67  ? 274 SER   A CB    1 
ATOM   2321 O OG    . SER   C 2 262 ? 191.424 241.567 222.030 1.00 48.90  ? 274 SER   A OG    1 
ATOM   2322 N N     . CYS   C 2 263 ? 190.674 236.929 221.003 1.00 43.37  ? 275 CYS   A N     1 
ATOM   2323 C CA    . CYS   C 2 263 ? 190.007 235.865 220.264 1.00 43.29  ? 275 CYS   A CA    1 
ATOM   2324 C C     . CYS   C 2 263 ? 188.646 235.612 220.902 1.00 45.20  ? 275 CYS   A C     1 
ATOM   2325 O O     . CYS   C 2 263 ? 188.558 235.033 221.988 1.00 46.97  ? 275 CYS   A O     1 
ATOM   2326 C CB    . CYS   C 2 263 ? 190.867 234.606 220.246 1.00 44.15  ? 275 CYS   A CB    1 
ATOM   2327 S SG    . CYS   C 2 263 ? 192.375 234.797 219.280 1.00 59.43  ? 275 CYS   A SG    1 
ATOM   2328 N N     . LEU   C 2 264 ? 187.592 236.050 220.230 1.00 45.77  ? 276 LEU   A N     1 
ATOM   2329 C CA    . LEU   C 2 264 ? 186.227 236.002 220.725 1.00 45.31  ? 276 LEU   A CA    1 
ATOM   2330 C C     . LEU   C 2 264 ? 185.600 234.641 220.455 1.00 48.70  ? 276 LEU   A C     1 
ATOM   2331 O O     . LEU   C 2 264 ? 186.043 233.904 219.570 1.00 50.83  ? 276 LEU   A O     1 
ATOM   2332 C CB    . LEU   C 2 264 ? 185.397 237.099 220.063 1.00 43.87  ? 276 LEU   A CB    1 
ATOM   2333 C CG    . LEU   C 2 264 ? 185.772 238.542 220.395 1.00 43.54  ? 276 LEU   A CG    1 
ATOM   2334 C CD1   . LEU   C 2 264 ? 184.639 239.478 220.029 1.00 44.53  ? 276 LEU   A CD1   1 
ATOM   2335 C CD2   . LEU   C 2 264 ? 186.129 238.682 221.860 1.00 43.98  ? 276 LEU   A CD2   1 
ATOM   2336 N N     . PRO   C 2 265 ? 184.566 234.275 221.209 1.00 45.13  ? 277 PRO   A N     1 
ATOM   2337 C CA    . PRO   C 2 265 ? 183.848 233.031 220.914 1.00 42.56  ? 277 PRO   A CA    1 
ATOM   2338 C C     . PRO   C 2 265 ? 183.142 233.097 219.568 1.00 43.89  ? 277 PRO   A C     1 
ATOM   2339 O O     . PRO   C 2 265 ? 182.798 234.171 219.070 1.00 45.90  ? 277 PRO   A O     1 
ATOM   2340 C CB    . PRO   C 2 265 ? 182.844 232.917 222.067 1.00 43.18  ? 277 PRO   A CB    1 
ATOM   2341 C CG    . PRO   C 2 265 ? 182.704 234.306 222.584 1.00 43.69  ? 277 PRO   A CG    1 
ATOM   2342 C CD    . PRO   C 2 265 ? 184.050 234.929 222.422 1.00 42.54  ? 277 PRO   A CD    1 
ATOM   2343 N N     . ALA   C 2 266 ? 182.938 231.919 218.976 1.00 46.86  ? 278 ALA   A N     1 
ATOM   2344 C CA    . ALA   C 2 266 ? 182.367 231.837 217.635 1.00 46.71  ? 278 ALA   A CA    1 
ATOM   2345 C C     . ALA   C 2 266 ? 180.941 232.364 217.566 1.00 45.86  ? 278 ALA   A C     1 
ATOM   2346 O O     . ALA   C 2 266 ? 180.478 232.713 216.474 1.00 44.77  ? 278 ALA   A O     1 
ATOM   2347 C CB    . ALA   C 2 266 ? 182.405 230.393 217.136 1.00 47.17  ? 278 ALA   A CB    1 
ATOM   2348 N N     . CYS   C 2 267 ? 180.233 232.426 218.695 1.00 45.70  ? 279 CYS   A N     1 
ATOM   2349 C CA    . CYS   C 2 267 ? 178.870 232.949 218.683 1.00 44.48  ? 279 CYS   A CA    1 
ATOM   2350 C C     . CYS   C 2 267 ? 178.845 234.416 218.274 1.00 43.33  ? 279 CYS   A C     1 
ATOM   2351 O O     . CYS   C 2 267 ? 177.956 234.844 217.530 1.00 43.67  ? 279 CYS   A O     1 
ATOM   2352 C CB    . CYS   C 2 267 ? 178.220 232.758 220.053 1.00 44.58  ? 279 CYS   A CB    1 
ATOM   2353 S SG    . CYS   C 2 267 ? 179.360 232.841 221.442 1.00 65.06  ? 279 CYS   A SG    1 
ATOM   2354 N N     . VAL   C 2 268 ? 179.812 235.201 218.752 1.00 42.17  ? 280 VAL   A N     1 
ATOM   2355 C CA    . VAL   C 2 268 ? 179.861 236.619 218.407 1.00 42.32  ? 280 VAL   A CA    1 
ATOM   2356 C C     . VAL   C 2 268 ? 180.104 236.802 216.914 1.00 41.73  ? 280 VAL   A C     1 
ATOM   2357 O O     . VAL   C 2 268 ? 179.445 237.619 216.258 1.00 42.73  ? 280 VAL   A O     1 
ATOM   2358 C CB    . VAL   C 2 268 ? 180.937 237.330 219.249 1.00 45.10  ? 280 VAL   A CB    1 
ATOM   2359 C CG1   . VAL   C 2 268 ? 180.987 238.801 218.907 1.00 47.52  ? 280 VAL   A CG1   1 
ATOM   2360 C CG2   . VAL   C 2 268 ? 180.664 237.136 220.728 1.00 43.89  ? 280 VAL   A CG2   1 
ATOM   2361 N N     . TYR   C 2 269 ? 181.052 236.047 216.354 1.00 42.32  ? 281 TYR   A N     1 
ATOM   2362 C CA    . TYR   C 2 269 ? 181.317 236.134 214.921 1.00 41.50  ? 281 TYR   A CA    1 
ATOM   2363 C C     . TYR   C 2 269 ? 180.112 235.683 214.106 1.00 41.06  ? 281 TYR   A C     1 
ATOM   2364 O O     . TYR   C 2 269 ? 179.793 236.281 213.072 1.00 41.13  ? 281 TYR   A O     1 
ATOM   2365 C CB    . TYR   C 2 269 ? 182.548 235.303 214.561 1.00 42.81  ? 281 TYR   A CB    1 
ATOM   2366 C CG    . TYR   C 2 269 ? 183.802 235.686 215.313 1.00 44.63  ? 281 TYR   A CG    1 
ATOM   2367 C CD1   . TYR   C 2 269 ? 184.125 237.016 215.528 1.00 45.11  ? 281 TYR   A CD1   1 
ATOM   2368 C CD2   . TYR   C 2 269 ? 184.667 234.717 215.796 1.00 43.68  ? 281 TYR   A CD2   1 
ATOM   2369 C CE1   . TYR   C 2 269 ? 185.272 237.369 216.209 1.00 43.61  ? 281 TYR   A CE1   1 
ATOM   2370 C CE2   . TYR   C 2 269 ? 185.815 235.061 216.479 1.00 41.67  ? 281 TYR   A CE2   1 
ATOM   2371 C CZ    . TYR   C 2 269 ? 186.113 236.388 216.681 1.00 43.64  ? 281 TYR   A CZ    1 
ATOM   2372 O OH    . TYR   C 2 269 ? 187.256 236.733 217.359 1.00 48.78  ? 281 TYR   A OH    1 
ATOM   2373 N N     . GLY   C 2 270 ? 179.433 234.624 214.551 1.00 42.64  ? 282 GLY   A N     1 
ATOM   2374 C CA    . GLY   C 2 270 ? 178.238 234.181 213.851 1.00 41.75  ? 282 GLY   A CA    1 
ATOM   2375 C C     . GLY   C 2 270 ? 177.130 235.214 213.874 1.00 43.32  ? 282 GLY   A C     1 
ATOM   2376 O O     . GLY   C 2 270 ? 176.451 235.432 212.868 1.00 46.93  ? 282 GLY   A O     1 
ATOM   2377 N N     . SER   C 2 271 ? 176.930 235.863 215.022 1.00 41.54  ? 283 SER   A N     1 
ATOM   2378 C CA    . SER   C 2 271 ? 175.931 236.923 215.109 1.00 41.04  ? 283 SER   A CA    1 
ATOM   2379 C C     . SER   C 2 271 ? 176.296 238.095 214.209 1.00 40.92  ? 283 SER   A C     1 
ATOM   2380 O O     . SER   C 2 271 ? 175.425 238.681 213.555 1.00 42.51  ? 283 SER   A O     1 
ATOM   2381 C CB    . SER   C 2 271 ? 175.782 237.389 216.557 1.00 41.34  ? 283 SER   A CB    1 
ATOM   2382 O OG    . SER   C 2 271 ? 174.866 236.574 217.264 1.00 52.53  ? 283 SER   A OG    1 
ATOM   2383 N N     . ALA   C 2 272 ? 177.580 238.456 214.167 1.00 40.95  ? 284 ALA   A N     1 
ATOM   2384 C CA    . ALA   C 2 272 ? 178.010 239.552 213.306 1.00 39.93  ? 284 ALA   A CA    1 
ATOM   2385 C C     . ALA   C 2 272 ? 177.801 239.219 211.834 1.00 40.25  ? 284 ALA   A C     1 
ATOM   2386 O O     . ALA   C 2 272 ? 177.394 240.081 211.047 1.00 43.11  ? 284 ALA   A O     1 
ATOM   2387 C CB    . ALA   C 2 272 ? 179.475 239.887 213.578 1.00 42.43  ? 284 ALA   A CB    1 
ATOM   2388 N N     . VAL   C 2 273 ? 178.087 237.977 211.441 1.00 40.57  ? 285 VAL   A N     1 
ATOM   2389 C CA    . VAL   C 2 273 ? 177.890 237.576 210.051 1.00 41.88  ? 285 VAL   A CA    1 
ATOM   2390 C C     . VAL   C 2 273 ? 176.405 237.533 209.712 1.00 43.21  ? 285 VAL   A C     1 
ATOM   2391 O O     . VAL   C 2 273 ? 175.994 237.918 208.610 1.00 41.87  ? 285 VAL   A O     1 
ATOM   2392 C CB    . VAL   C 2 273 ? 178.582 236.226 209.785 1.00 38.26  ? 285 VAL   A CB    1 
ATOM   2393 C CG1   . VAL   C 2 273 ? 178.111 235.625 208.473 1.00 38.92  ? 285 VAL   A CG1   1 
ATOM   2394 C CG2   . VAL   C 2 273 ? 180.087 236.401 209.774 1.00 39.88  ? 285 VAL   A CG2   1 
ATOM   2395 N N     . ALA   C 2 274 ? 175.576 237.072 210.650 1.00 41.02  ? 286 ALA   A N     1 
ATOM   2396 C CA    . ALA   C 2 274 ? 174.134 237.095 210.432 1.00 38.39  ? 286 ALA   A CA    1 
ATOM   2397 C C     . ALA   C 2 274 ? 173.606 238.519 210.340 1.00 43.36  ? 286 ALA   A C     1 
ATOM   2398 O O     . ALA   C 2 274 ? 172.684 238.789 209.561 1.00 49.51  ? 286 ALA   A O     1 
ATOM   2399 C CB    . ALA   C 2 274 ? 173.417 236.335 211.548 1.00 37.00  ? 286 ALA   A CB    1 
ATOM   2400 N N     . SER   C 2 275 ? 174.173 239.440 211.119 1.00 42.31  ? 287 SER   A N     1 
ATOM   2401 C CA    . SER   C 2 275 ? 173.737 240.830 211.078 1.00 40.81  ? 287 SER   A CA    1 
ATOM   2402 C C     . SER   C 2 275 ? 174.167 241.546 209.805 1.00 43.43  ? 287 SER   A C     1 
ATOM   2403 O O     . SER   C 2 275 ? 173.726 242.676 209.575 1.00 48.31  ? 287 SER   A O     1 
ATOM   2404 C CB    . SER   C 2 275 ? 174.267 241.582 212.298 1.00 44.39  ? 287 SER   A CB    1 
ATOM   2405 O OG    . SER   C 2 275 ? 173.629 241.140 213.482 1.00 49.63  ? 287 SER   A OG    1 
ATOM   2406 N N     . GLY   C 2 276 ? 175.009 240.926 208.982 1.00 42.52  ? 288 GLY   A N     1 
ATOM   2407 C CA    . GLY   C 2 276 ? 175.409 241.497 207.717 1.00 42.95  ? 288 GLY   A CA    1 
ATOM   2408 C C     . GLY   C 2 276 ? 176.791 242.106 207.684 1.00 47.55  ? 288 GLY   A C     1 
ATOM   2409 O O     . GLY   C 2 276 ? 177.191 242.628 206.636 1.00 52.78  ? 288 GLY   A O     1 
ATOM   2410 N N     . TYR   C 2 277 ? 177.529 242.069 208.790 1.00 47.93  ? 289 TYR   A N     1 
ATOM   2411 C CA    . TYR   C 2 277 ? 178.883 242.604 208.802 1.00 47.48  ? 289 TYR   A CA    1 
ATOM   2412 C C     . TYR   C 2 277 ? 179.757 241.827 207.826 1.00 49.79  ? 289 TYR   A C     1 
ATOM   2413 O O     . TYR   C 2 277 ? 179.757 240.593 207.819 1.00 51.47  ? 289 TYR   A O     1 
ATOM   2414 C CB    . TYR   C 2 277 ? 179.462 242.531 210.216 1.00 46.43  ? 289 TYR   A CB    1 
ATOM   2415 C CG    . TYR   C 2 277 ? 180.610 243.479 210.504 1.00 46.38  ? 289 TYR   A CG    1 
ATOM   2416 C CD1   . TYR   C 2 277 ? 181.679 243.604 209.629 1.00 48.48  ? 289 TYR   A CD1   1 
ATOM   2417 C CD2   . TYR   C 2 277 ? 180.631 244.236 211.664 1.00 47.04  ? 289 TYR   A CD2   1 
ATOM   2418 C CE1   . TYR   C 2 277 ? 182.725 244.460 209.893 1.00 47.36  ? 289 TYR   A CE1   1 
ATOM   2419 C CE2   . TYR   C 2 277 ? 181.675 245.094 211.938 1.00 46.53  ? 289 TYR   A CE2   1 
ATOM   2420 C CZ    . TYR   C 2 277 ? 182.719 245.201 211.049 1.00 45.04  ? 289 TYR   A CZ    1 
ATOM   2421 O OH    . TYR   C 2 277 ? 183.762 246.055 211.313 1.00 48.25  ? 289 TYR   A OH    1 
ATOM   2422 N N     . ASP   C 2 278 ? 180.494 242.554 206.997 1.00 48.12  ? 290 ASP   A N     1 
ATOM   2423 C CA    . ASP   C 2 278 ? 181.445 241.965 206.060 1.00 48.91  ? 290 ASP   A CA    1 
ATOM   2424 C C     . ASP   C 2 278 ? 182.846 242.221 206.602 1.00 51.37  ? 290 ASP   A C     1 
ATOM   2425 O O     . ASP   C 2 278 ? 183.423 243.288 206.377 1.00 54.32  ? 290 ASP   A O     1 
ATOM   2426 C CB    . ASP   C 2 278 ? 181.272 242.547 204.662 1.00 52.97  ? 290 ASP   A CB    1 
ATOM   2427 C CG    . ASP   C 2 278 ? 181.662 241.571 203.576 1.00 64.19  ? 290 ASP   A CG    1 
ATOM   2428 O OD1   . ASP   C 2 278 ? 182.813 241.088 203.598 1.00 62.31  ? 290 ASP   A OD1   1 
ATOM   2429 O OD2   . ASP   C 2 278 ? 180.818 241.281 202.704 1.00 78.47  ? 290 ASP   A OD2   1 
ATOM   2430 N N     . PHE   C 2 279 ? 183.388 241.240 207.323 1.00 48.49  ? 291 PHE   A N     1 
ATOM   2431 C CA    . PHE   C 2 279 ? 184.739 241.383 207.849 1.00 47.91  ? 291 PHE   A CA    1 
ATOM   2432 C C     . PHE   C 2 279 ? 185.773 241.396 206.732 1.00 48.91  ? 291 PHE   A C     1 
ATOM   2433 O O     . PHE   C 2 279 ? 186.851 241.973 206.895 1.00 51.69  ? 291 PHE   A O     1 
ATOM   2434 C CB    . PHE   C 2 279 ? 185.041 240.261 208.840 1.00 47.32  ? 291 PHE   A CB    1 
ATOM   2435 C CG    . PHE   C 2 279 ? 184.225 240.324 210.095 1.00 46.85  ? 291 PHE   A CG    1 
ATOM   2436 C CD1   . PHE   C 2 279 ? 184.567 241.192 211.115 1.00 50.40  ? 291 PHE   A CD1   1 
ATOM   2437 C CD2   . PHE   C 2 279 ? 183.118 239.512 210.258 1.00 45.88  ? 291 PHE   A CD2   1 
ATOM   2438 C CE1   . PHE   C 2 279 ? 183.820 241.250 212.271 1.00 49.19  ? 291 PHE   A CE1   1 
ATOM   2439 C CE2   . PHE   C 2 279 ? 182.369 239.567 211.413 1.00 45.06  ? 291 PHE   A CE2   1 
ATOM   2440 C CZ    . PHE   C 2 279 ? 182.721 240.436 212.420 1.00 45.15  ? 291 PHE   A CZ    1 
ATOM   2441 N N     . GLU   C 2 280 ? 185.467 240.763 205.601 1.00 49.83  ? 292 GLU   A N     1 
ATOM   2442 C CA    . GLU   C 2 280 ? 186.384 240.787 204.466 1.00 50.55  ? 292 GLU   A CA    1 
ATOM   2443 C C     . GLU   C 2 280 ? 186.549 242.200 203.917 1.00 53.07  ? 292 GLU   A C     1 
ATOM   2444 O O     . GLU   C 2 280 ? 187.669 242.628 203.616 1.00 54.30  ? 292 GLU   A O     1 
ATOM   2445 C CB    . GLU   C 2 280 ? 185.887 239.839 203.378 1.00 48.91  ? 292 GLU   A CB    1 
ATOM   2446 C CG    . GLU   C 2 280 ? 186.653 239.938 202.076 1.00 56.28  ? 292 GLU   A CG    1 
ATOM   2447 C CD    . GLU   C 2 280 ? 188.012 239.281 202.156 1.00 60.53  ? 292 GLU   A CD    1 
ATOM   2448 O OE1   . GLU   C 2 280 ? 188.987 239.973 202.510 1.00 61.20  ? 292 GLU   A OE1   1 
ATOM   2449 O OE2   . GLU   C 2 280 ? 188.104 238.072 201.861 1.00 64.16  ? 292 GLU   A OE2   1 
ATOM   2450 N N     . ARG   C 2 281 ? 185.448 242.939 203.785 1.00 52.27  ? 293 ARG   A N     1 
ATOM   2451 C CA    . ARG   C 2 281 ? 185.512 244.294 203.248 1.00 50.05  ? 293 ARG   A CA    1 
ATOM   2452 C C     . ARG   C 2 281 ? 186.039 245.280 204.284 1.00 48.76  ? 293 ARG   A C     1 
ATOM   2453 O O     . ARG   C 2 281 ? 186.971 246.044 204.012 1.00 52.81  ? 293 ARG   A O     1 
ATOM   2454 C CB    . ARG   C 2 281 ? 184.131 244.728 202.755 1.00 55.87  ? 293 ARG   A CB    1 
ATOM   2455 C CG    . ARG   C 2 281 ? 183.744 244.166 201.400 1.00 64.41  ? 293 ARG   A CG    1 
ATOM   2456 C CD    . ARG   C 2 281 ? 182.232 244.176 201.187 1.00 70.47  ? 293 ARG   A CD    1 
ATOM   2457 N NE    . ARG   C 2 281 ? 181.531 245.140 202.029 1.00 69.69  ? 293 ARG   A NE    1 
ATOM   2458 C CZ    . ARG   C 2 281 ? 181.510 246.449 201.819 1.00 72.59  ? 293 ARG   A CZ    1 
ATOM   2459 N NH1   . ARG   C 2 281 ? 182.139 246.995 200.791 1.00 74.89  ? 293 ARG   A NH1   1 
ATOM   2460 N NH2   . ARG   C 2 281 ? 180.841 247.229 202.662 1.00 75.24  ? 293 ARG   A NH2   1 
ATOM   2461 N N     . GLU   C 2 282 ? 185.446 245.281 205.477 1.00 47.11  ? 294 GLU   A N     1 
ATOM   2462 C CA    . GLU   C 2 282 ? 185.839 246.240 206.502 1.00 47.89  ? 294 GLU   A CA    1 
ATOM   2463 C C     . GLU   C 2 282 ? 187.188 245.912 207.129 1.00 49.04  ? 294 GLU   A C     1 
ATOM   2464 O O     . GLU   C 2 282 ? 187.879 246.827 207.587 1.00 52.57  ? 294 GLU   A O     1 
ATOM   2465 C CB    . GLU   C 2 282 ? 184.767 246.317 207.587 1.00 51.16  ? 294 GLU   A CB    1 
ATOM   2466 C CG    . GLU   C 2 282 ? 183.358 246.513 207.056 1.00 57.39  ? 294 GLU   A CG    1 
ATOM   2467 C CD    . GLU   C 2 282 ? 183.058 247.956 206.705 1.00 70.63  ? 294 GLU   A CD    1 
ATOM   2468 O OE1   . GLU   C 2 282 ? 183.666 248.480 205.749 1.00 72.50  ? 294 GLU   A OE1   1 
ATOM   2469 O OE2   . GLU   C 2 282 ? 182.213 248.569 207.388 1.00 75.33  ? 294 GLU   A OE2   1 
ATOM   2470 N N     . GLY   C 2 283 ? 187.580 244.645 207.158 1.00 47.84  ? 295 GLY   A N     1 
ATOM   2471 C CA    . GLY   C 2 283 ? 188.821 244.258 207.798 1.00 45.44  ? 295 GLY   A CA    1 
ATOM   2472 C C     . GLY   C 2 283 ? 188.643 243.955 209.270 1.00 46.78  ? 295 GLY   A C     1 
ATOM   2473 O O     . GLY   C 2 283 ? 187.573 244.121 209.861 1.00 48.98  ? 295 GLY   A O     1 
ATOM   2474 N N     . TYR   C 2 284 ? 189.733 243.494 209.878 1.00 47.82  ? 296 TYR   A N     1 
ATOM   2475 C CA    . TYR   C 2 284 ? 189.721 243.130 211.286 1.00 46.36  ? 296 TYR   A CA    1 
ATOM   2476 C C     . TYR   C 2 284 ? 191.130 243.251 211.848 1.00 47.99  ? 296 TYR   A C     1 
ATOM   2477 O O     . TYR   C 2 284 ? 192.111 243.333 211.105 1.00 50.60  ? 296 TYR   A O     1 
ATOM   2478 C CB    . TYR   C 2 284 ? 189.179 241.711 211.489 1.00 45.13  ? 296 TYR   A CB    1 
ATOM   2479 C CG    . TYR   C 2 284 ? 188.571 241.472 212.850 1.00 46.20  ? 296 TYR   A CG    1 
ATOM   2480 C CD1   . TYR   C 2 284 ? 187.343 242.018 213.187 1.00 42.52  ? 296 TYR   A CD1   1 
ATOM   2481 C CD2   . TYR   C 2 284 ? 189.220 240.689 213.793 1.00 45.64  ? 296 TYR   A CD2   1 
ATOM   2482 C CE1   . TYR   C 2 284 ? 186.783 241.800 214.428 1.00 40.06  ? 296 TYR   A CE1   1 
ATOM   2483 C CE2   . TYR   C 2 284 ? 188.666 240.465 215.036 1.00 42.59  ? 296 TYR   A CE2   1 
ATOM   2484 C CZ    . TYR   C 2 284 ? 187.449 241.021 215.348 1.00 43.35  ? 296 TYR   A CZ    1 
ATOM   2485 O OH    . TYR   C 2 284 ? 186.895 240.800 216.584 1.00 47.89  ? 296 TYR   A OH    1 
ATOM   2486 N N     . SER   C 2 285 ? 191.214 243.283 213.174 1.00 47.63  ? 297 SER   A N     1 
ATOM   2487 C CA    . SER   C 2 285 ? 192.503 243.324 213.862 1.00 44.72  ? 297 SER   A CA    1 
ATOM   2488 C C     . SER   C 2 285 ? 192.292 242.830 215.282 1.00 44.99  ? 297 SER   A C     1 
ATOM   2489 O O     . SER   C 2 285 ? 191.442 243.362 216.001 1.00 45.48  ? 297 SER   A O     1 
ATOM   2490 C CB    . SER   C 2 285 ? 193.088 244.736 213.860 1.00 43.34  ? 297 SER   A CB    1 
ATOM   2491 O OG    . SER   C 2 285 ? 192.303 245.613 214.645 1.00 51.57  ? 297 SER   A OG    1 
ATOM   2492 N N     . LEU   C 2 286 ? 193.058 241.818 215.683 1.00 43.96  ? 298 LEU   A N     1 
ATOM   2493 C CA    . LEU   C 2 286 ? 192.902 241.227 217.005 1.00 42.31  ? 298 LEU   A CA    1 
ATOM   2494 C C     . LEU   C 2 286 ? 193.436 242.114 218.122 1.00 45.07  ? 298 LEU   A C     1 
ATOM   2495 O O     . LEU   C 2 286 ? 193.206 241.802 219.294 1.00 45.73  ? 298 LEU   A O     1 
ATOM   2496 C CB    . LEU   C 2 286 ? 193.601 239.868 217.048 1.00 39.75  ? 298 LEU   A CB    1 
ATOM   2497 C CG    . LEU   C 2 286 ? 193.144 238.857 215.996 1.00 39.44  ? 298 LEU   A CG    1 
ATOM   2498 C CD1   . LEU   C 2 286 ? 193.887 237.544 216.151 1.00 44.40  ? 298 LEU   A CD1   1 
ATOM   2499 C CD2   . LEU   C 2 286 ? 191.646 238.639 216.079 1.00 42.36  ? 298 LEU   A CD2   1 
ATOM   2500 N N     . VAL   C 2 287 ? 194.134 243.200 217.798 1.00 46.26  ? 299 VAL   A N     1 
ATOM   2501 C CA    . VAL   C 2 287 ? 194.730 244.070 218.806 1.00 43.87  ? 299 VAL   A CA    1 
ATOM   2502 C C     . VAL   C 2 287 ? 194.128 245.466 218.822 1.00 44.63  ? 299 VAL   A C     1 
ATOM   2503 O O     . VAL   C 2 287 ? 194.388 246.221 219.772 1.00 45.31  ? 299 VAL   A O     1 
ATOM   2504 C CB    . VAL   C 2 287 ? 196.260 244.167 218.632 1.00 41.80  ? 299 VAL   A CB    1 
ATOM   2505 C CG1   . VAL   C 2 287 ? 196.905 242.814 218.860 1.00 44.10  ? 299 VAL   A CG1   1 
ATOM   2506 C CG2   . VAL   C 2 287 ? 196.599 244.695 217.252 1.00 41.55  ? 299 VAL   A CG2   1 
ATOM   2507 N N     . GLY   C 2 288 ? 193.339 245.833 217.823 1.00 45.67  ? 300 GLY   A N     1 
ATOM   2508 C CA    . GLY   C 2 288 ? 192.793 247.172 217.709 1.00 43.77  ? 300 GLY   A CA    1 
ATOM   2509 C C     . GLY   C 2 288 ? 191.431 247.327 218.346 1.00 45.47  ? 300 GLY   A C     1 
ATOM   2510 O O     . GLY   C 2 288 ? 191.079 246.631 219.303 1.00 48.00  ? 300 GLY   A O     1 
ATOM   2511 N N     . ILE   C 2 289 ? 190.655 248.267 217.807 1.00 43.84  ? 301 ILE   A N     1 
ATOM   2512 C CA    . ILE   C 2 289 ? 189.323 248.548 218.331 1.00 42.58  ? 301 ILE   A CA    1 
ATOM   2513 C C     . ILE   C 2 289 ? 188.296 247.517 217.882 1.00 44.59  ? 301 ILE   A C     1 
ATOM   2514 O O     . ILE   C 2 289 ? 187.274 247.336 218.557 1.00 49.07  ? 301 ILE   A O     1 
ATOM   2515 C CB    . ILE   C 2 289 ? 188.884 249.962 217.909 1.00 42.34  ? 301 ILE   A CB    1 
ATOM   2516 C CG1   . ILE   C 2 289 ? 187.513 250.313 218.489 1.00 40.29  ? 301 ILE   A CG1   1 
ATOM   2517 C CG2   . ILE   C 2 289 ? 188.867 250.085 216.395 1.00 40.63  ? 301 ILE   A CG2   1 
ATOM   2518 C CD1   . ILE   C 2 289 ? 187.107 251.744 218.267 1.00 48.44  ? 301 ILE   A CD1   1 
ATOM   2519 N N     . ASP   C 2 290 ? 188.553 246.816 216.778 1.00 43.31  ? 302 ASP   A N     1 
ATOM   2520 C CA    . ASP   C 2 290 ? 187.598 245.910 216.147 1.00 42.00  ? 302 ASP   A CA    1 
ATOM   2521 C C     . ASP   C 2 290 ? 186.991 244.902 217.123 1.00 40.83  ? 302 ASP   A C     1 
ATOM   2522 O O     . ASP   C 2 290 ? 185.769 244.713 217.108 1.00 39.86  ? 302 ASP   A O     1 
ATOM   2523 C CB    . ASP   C 2 290 ? 188.261 245.180 214.976 1.00 46.28  ? 302 ASP   A CB    1 
ATOM   2524 C CG    . ASP   C 2 290 ? 188.665 246.120 213.857 1.00 49.00  ? 302 ASP   A CG    1 
ATOM   2525 O OD1   . ASP   C 2 290 ? 189.628 246.891 214.044 1.00 47.66  ? 302 ASP   A OD1   1 
ATOM   2526 O OD2   . ASP   C 2 290 ? 188.020 246.091 212.789 1.00 49.78  ? 302 ASP   A OD2   1 
ATOM   2527 N N     . PRO   C 2 291 ? 187.777 244.233 217.977 1.00 42.64  ? 303 PRO   A N     1 
ATOM   2528 C CA    . PRO   C 2 291 ? 187.140 243.336 218.957 1.00 41.41  ? 303 PRO   A CA    1 
ATOM   2529 C C     . PRO   C 2 291 ? 186.320 244.080 219.992 1.00 42.12  ? 303 PRO   A C     1 
ATOM   2530 O O     . PRO   C 2 291 ? 185.223 243.633 220.344 1.00 45.45  ? 303 PRO   A O     1 
ATOM   2531 C CB    . PRO   C 2 291 ? 188.330 242.604 219.594 1.00 40.14  ? 303 PRO   A CB    1 
ATOM   2532 C CG    . PRO   C 2 291 ? 189.472 242.831 218.672 1.00 42.87  ? 303 PRO   A CG    1 
ATOM   2533 C CD    . PRO   C 2 291 ? 189.243 244.184 218.101 1.00 43.66  ? 303 PRO   A CD    1 
ATOM   2534 N N     . PHE   C 2 292 ? 186.833 245.202 220.498 1.00 41.89  ? 304 PHE   A N     1 
ATOM   2535 C CA    . PHE   C 2 292 ? 186.121 245.958 221.521 1.00 40.27  ? 304 PHE   A CA    1 
ATOM   2536 C C     . PHE   C 2 292 ? 184.794 246.481 220.991 1.00 41.75  ? 304 PHE   A C     1 
ATOM   2537 O O     . PHE   C 2 292 ? 183.767 246.422 221.677 1.00 43.59  ? 304 PHE   A O     1 
ATOM   2538 C CB    . PHE   C 2 292 ? 186.995 247.112 222.009 1.00 41.54  ? 304 PHE   A CB    1 
ATOM   2539 C CG    . PHE   C 2 292 ? 187.783 246.796 223.241 1.00 44.81  ? 304 PHE   A CG    1 
ATOM   2540 C CD1   . PHE   C 2 292 ? 187.144 246.507 224.431 1.00 49.15  ? 304 PHE   A CD1   1 
ATOM   2541 C CD2   . PHE   C 2 292 ? 189.163 246.794 223.212 1.00 41.86  ? 304 PHE   A CD2   1 
ATOM   2542 C CE1   . PHE   C 2 292 ? 187.867 246.220 225.567 1.00 49.26  ? 304 PHE   A CE1   1 
ATOM   2543 C CE2   . PHE   C 2 292 ? 189.889 246.511 224.346 1.00 40.33  ? 304 PHE   A CE2   1 
ATOM   2544 C CZ    . PHE   C 2 292 ? 189.242 246.222 225.523 1.00 43.94  ? 304 PHE   A CZ    1 
ATOM   2545 N N     . ARG   C 2 293 ? 184.801 247.009 219.766 1.00 42.46  ? 305 ARG   A N     1 
ATOM   2546 C CA    . ARG   C 2 293 ? 183.572 247.488 219.146 1.00 40.08  ? 305 ARG   A CA    1 
ATOM   2547 C C     . ARG   C 2 293 ? 182.583 246.348 218.941 1.00 40.43  ? 305 ARG   A C     1 
ATOM   2548 O O     . ARG   C 2 293 ? 181.385 246.491 219.204 1.00 44.24  ? 305 ARG   A O     1 
ATOM   2549 C CB    . ARG   C 2 293 ? 183.903 248.166 217.818 1.00 40.89  ? 305 ARG   A CB    1 
ATOM   2550 C CG    . ARG   C 2 293 ? 182.801 248.114 216.786 1.00 41.02  ? 305 ARG   A CG    1 
ATOM   2551 C CD    . ARG   C 2 293 ? 183.093 249.082 215.663 1.00 41.83  ? 305 ARG   A CD    1 
ATOM   2552 N NE    . ARG   C 2 293 ? 184.213 248.620 214.853 1.00 41.80  ? 305 ARG   A NE    1 
ATOM   2553 C CZ    . ARG   C 2 293 ? 184.966 249.406 214.098 1.00 45.62  ? 305 ARG   A CZ    1 
ATOM   2554 N NH1   . ARG   C 2 293 ? 184.743 250.706 214.019 1.00 51.44  ? 305 ARG   A NH1   1 
ATOM   2555 N NH2   . ARG   C 2 293 ? 185.967 248.874 213.404 1.00 43.78  ? 305 ARG   A NH2   1 
ATOM   2556 N N     . LEU   C 2 294 ? 183.077 245.200 218.473 1.00 40.94  ? 306 LEU   A N     1 
ATOM   2557 C CA    . LEU   C 2 294 ? 182.209 244.054 218.229 1.00 41.12  ? 306 LEU   A CA    1 
ATOM   2558 C C     . LEU   C 2 294 ? 181.568 243.564 219.523 1.00 41.95  ? 306 LEU   A C     1 
ATOM   2559 O O     . LEU   C 2 294 ? 180.380 243.226 219.553 1.00 40.95  ? 306 LEU   A O     1 
ATOM   2560 C CB    . LEU   C 2 294 ? 183.012 242.940 217.557 1.00 38.67  ? 306 LEU   A CB    1 
ATOM   2561 C CG    . LEU   C 2 294 ? 182.277 241.663 217.164 1.00 39.00  ? 306 LEU   A CG    1 
ATOM   2562 C CD1   . LEU   C 2 294 ? 181.240 241.954 216.100 1.00 41.65  ? 306 LEU   A CD1   1 
ATOM   2563 C CD2   . LEU   C 2 294 ? 183.264 240.624 216.674 1.00 39.09  ? 306 LEU   A CD2   1 
ATOM   2564 N N     . LEU   C 2 295 ? 182.346 243.522 220.605 1.00 41.75  ? 307 LEU   A N     1 
ATOM   2565 C CA    . LEU   C 2 295 ? 181.814 243.088 221.893 1.00 41.17  ? 307 LEU   A CA    1 
ATOM   2566 C C     . LEU   C 2 295 ? 180.742 244.047 222.398 1.00 45.15  ? 307 LEU   A C     1 
ATOM   2567 O O     . LEU   C 2 295 ? 179.785 243.633 223.063 1.00 47.19  ? 307 LEU   A O     1 
ATOM   2568 C CB    . LEU   C 2 295 ? 182.945 242.963 222.911 1.00 39.03  ? 307 LEU   A CB    1 
ATOM   2569 C CG    . LEU   C 2 295 ? 183.589 241.585 223.057 1.00 39.26  ? 307 LEU   A CG    1 
ATOM   2570 C CD1   . LEU   C 2 295 ? 184.359 241.500 224.359 1.00 45.50  ? 307 LEU   A CD1   1 
ATOM   2571 C CD2   . LEU   C 2 295 ? 182.537 240.496 222.992 1.00 43.34  ? 307 LEU   A CD2   1 
ATOM   2572 N N     . GLN   C 2 296 ? 180.895 245.340 222.102 1.00 46.30  ? 308 GLN   A N     1 
ATOM   2573 C CA    . GLN   C 2 296 ? 179.931 246.331 222.568 1.00 44.10  ? 308 GLN   A CA    1 
ATOM   2574 C C     . GLN   C 2 296 ? 178.540 246.105 221.991 1.00 46.30  ? 308 GLN   A C     1 
ATOM   2575 O O     . GLN   C 2 296 ? 177.540 246.394 222.659 1.00 49.64  ? 308 GLN   A O     1 
ATOM   2576 C CB    . GLN   C 2 296 ? 180.418 247.737 222.216 1.00 41.92  ? 308 GLN   A CB    1 
ATOM   2577 C CG    . GLN   C 2 296 ? 179.940 248.816 223.169 1.00 41.13  ? 308 GLN   A CG    1 
ATOM   2578 C CD    . GLN   C 2 296 ? 180.802 248.932 224.404 1.00 48.82  ? 308 GLN   A CD    1 
ATOM   2579 O OE1   . GLN   C 2 296 ? 181.930 248.443 224.434 1.00 54.51  ? 308 GLN   A OE1   1 
ATOM   2580 N NE2   . GLN   C 2 296 ? 180.275 249.582 225.431 1.00 49.66  ? 308 GLN   A NE2   1 
ATOM   2581 N N     . ASN   C 2 297 ? 178.447 245.588 220.767 1.00 46.02  ? 309 ASN   A N     1 
ATOM   2582 C CA    . ASN   C 2 297 ? 177.170 245.493 220.065 1.00 45.47  ? 309 ASN   A CA    1 
ATOM   2583 C C     . ASN   C 2 297 ? 176.609 244.076 220.057 1.00 45.83  ? 309 ASN   A C     1 
ATOM   2584 O O     . ASN   C 2 297 ? 175.672 243.793 219.304 1.00 47.65  ? 309 ASN   A O     1 
ATOM   2585 C CB    . ASN   C 2 297 ? 177.309 245.995 218.627 1.00 46.69  ? 309 ASN   A CB    1 
ATOM   2586 C CG    . ASN   C 2 297 ? 178.204 247.210 218.512 1.00 52.23  ? 309 ASN   A CG    1 
ATOM   2587 O OD1   . ASN   C 2 297 ? 178.425 247.930 219.484 1.00 60.50  ? 309 ASN   A OD1   1 
ATOM   2588 N ND2   . ASN   C 2 297 ? 178.728 247.443 217.315 1.00 45.23  ? 309 ASN   A ND2   1 
ATOM   2589 N N     . SER   C 2 298 ? 177.147 243.178 220.876 1.00 44.50  ? 310 SER   A N     1 
ATOM   2590 C CA    . SER   C 2 298 ? 176.796 241.767 220.816 1.00 45.51  ? 310 SER   A CA    1 
ATOM   2591 C C     . SER   C 2 298 ? 176.205 241.305 222.139 1.00 44.10  ? 310 SER   A C     1 
ATOM   2592 O O     . SER   C 2 298 ? 176.668 241.705 223.212 1.00 44.56  ? 310 SER   A O     1 
ATOM   2593 C CB    . SER   C 2 298 ? 178.017 240.910 220.474 1.00 44.26  ? 310 SER   A CB    1 
ATOM   2594 O OG    . SER   C 2 298 ? 178.850 240.740 221.605 1.00 43.58  ? 310 SER   A OG    1 
ATOM   2595 N N     . GLN   C 2 299 ? 175.181 240.459 222.054 1.00 40.88  ? 311 GLN   A N     1 
ATOM   2596 C CA    . GLN   C 2 299 ? 174.565 239.838 223.217 1.00 42.15  ? 311 GLN   A CA    1 
ATOM   2597 C C     . GLN   C 2 299 ? 174.939 238.363 223.251 1.00 41.93  ? 311 GLN   A C     1 
ATOM   2598 O O     . GLN   C 2 299 ? 174.749 237.647 222.263 1.00 42.40  ? 311 GLN   A O     1 
ATOM   2599 C CB    . GLN   C 2 299 ? 173.043 240.006 223.195 1.00 42.67  ? 311 GLN   A CB    1 
ATOM   2600 C CG    . GLN   C 2 299 ? 172.383 239.657 221.872 1.00 44.91  ? 311 GLN   A CG    1 
ATOM   2601 C CD    . GLN   C 2 299 ? 171.051 240.353 221.684 1.00 50.88  ? 311 GLN   A CD    1 
ATOM   2602 O OE1   . GLN   C 2 299 ? 170.901 241.207 220.812 1.00 61.69  ? 311 GLN   A OE1   1 
ATOM   2603 N NE2   . GLN   C 2 299 ? 170.073 239.990 222.503 1.00 46.65  ? 311 GLN   A NE2   1 
ATOM   2604 N N     . VAL   C 2 300 ? 175.484 237.917 224.379 1.00 40.34  ? 312 VAL   A N     1 
ATOM   2605 C CA    . VAL   C 2 300 ? 175.897 236.533 224.568 1.00 41.83  ? 312 VAL   A CA    1 
ATOM   2606 C C     . VAL   C 2 300 ? 175.334 236.045 225.893 1.00 45.32  ? 312 VAL   A C     1 
ATOM   2607 O O     . VAL   C 2 300 ? 175.447 236.735 226.911 1.00 50.69  ? 312 VAL   A O     1 
ATOM   2608 C CB    . VAL   C 2 300 ? 177.430 236.382 224.536 1.00 41.61  ? 312 VAL   A CB    1 
ATOM   2609 C CG1   . VAL   C 2 300 ? 177.845 235.010 225.036 1.00 44.56  ? 312 VAL   A CG1   1 
ATOM   2610 C CG2   . VAL   C 2 300 ? 177.952 236.616 223.133 1.00 45.02  ? 312 VAL   A CG2   1 
ATOM   2611 N N     . TYR   C 2 301 ? 174.727 234.863 225.881 1.00 42.38  ? 313 TYR   A N     1 
ATOM   2612 C CA    . TYR   C 2 301 ? 174.107 234.289 227.062 1.00 44.63  ? 313 TYR   A CA    1 
ATOM   2613 C C     . TYR   C 2 301 ? 174.932 233.113 227.569 1.00 46.60  ? 313 TYR   A C     1 
ATOM   2614 O O     . TYR   C 2 301 ? 175.657 232.461 226.813 1.00 49.86  ? 313 TYR   A O     1 
ATOM   2615 C CB    . TYR   C 2 301 ? 172.674 233.842 226.759 1.00 47.94  ? 313 TYR   A CB    1 
ATOM   2616 C CG    . TYR   C 2 301 ? 171.837 234.915 226.104 1.00 47.75  ? 313 TYR   A CG    1 
ATOM   2617 C CD1   . TYR   C 2 301 ? 171.299 235.953 226.848 1.00 49.75  ? 313 TYR   A CD1   1 
ATOM   2618 C CD2   . TYR   C 2 301 ? 171.588 234.892 224.741 1.00 45.48  ? 313 TYR   A CD2   1 
ATOM   2619 C CE1   . TYR   C 2 301 ? 170.535 236.938 226.252 1.00 49.68  ? 313 TYR   A CE1   1 
ATOM   2620 C CE2   . TYR   C 2 301 ? 170.825 235.871 224.137 1.00 45.85  ? 313 TYR   A CE2   1 
ATOM   2621 C CZ    . TYR   C 2 301 ? 170.301 236.891 224.898 1.00 47.66  ? 313 TYR   A CZ    1 
ATOM   2622 O OH    . TYR   C 2 301 ? 169.542 237.867 224.302 1.00 50.58  ? 313 TYR   A OH    1 
ATOM   2623 N N     . SER   C 2 302 ? 174.816 232.848 228.868 1.00 45.67  ? 314 SER   A N     1 
ATOM   2624 C CA    . SER   C 2 302 ? 175.590 231.789 229.500 1.00 46.13  ? 314 SER   A CA    1 
ATOM   2625 C C     . SER   C 2 302 ? 174.766 231.150 230.605 1.00 46.94  ? 314 SER   A C     1 
ATOM   2626 O O     . SER   C 2 302 ? 173.873 231.775 231.181 1.00 48.09  ? 314 SER   A O     1 
ATOM   2627 C CB    . SER   C 2 302 ? 176.909 232.318 230.068 1.00 48.43  ? 314 SER   A CB    1 
ATOM   2628 O OG    . SER   C 2 302 ? 177.425 231.434 231.045 1.00 50.30  ? 314 SER   A OG    1 
ATOM   2629 N N     . LEU   C 2 303 ? 175.090 229.896 230.907 1.00 47.11  ? 315 LEU   A N     1 
ATOM   2630 C CA    . LEU   C 2 303 ? 174.370 229.149 231.929 1.00 48.67  ? 315 LEU   A CA    1 
ATOM   2631 C C     . LEU   C 2 303 ? 174.939 229.462 233.306 1.00 49.37  ? 315 LEU   A C     1 
ATOM   2632 O O     . LEU   C 2 303 ? 176.154 229.404 233.514 1.00 50.56  ? 315 LEU   A O     1 
ATOM   2633 C CB    . LEU   C 2 303 ? 174.449 227.650 231.652 1.00 46.38  ? 315 LEU   A CB    1 
ATOM   2634 C CG    . LEU   C 2 303 ? 173.717 227.155 230.405 1.00 44.15  ? 315 LEU   A CG    1 
ATOM   2635 C CD1   . LEU   C 2 303 ? 173.833 225.650 230.277 1.00 42.20  ? 315 LEU   A CD1   1 
ATOM   2636 C CD2   . LEU   C 2 303 ? 172.262 227.575 230.444 1.00 49.40  ? 315 LEU   A CD2   1 
ATOM   2637 N N     . ILE   C 2 304 ? 174.055 229.788 234.244 1.00 48.79  ? 316 ILE   A N     1 
ATOM   2638 C CA    . ILE   C 2 304 ? 174.437 230.159 235.601 1.00 45.81  ? 316 ILE   A CA    1 
ATOM   2639 C C     . ILE   C 2 304 ? 174.039 229.020 236.529 1.00 48.59  ? 316 ILE   A C     1 
ATOM   2640 O O     . ILE   C 2 304 ? 172.865 228.637 236.591 1.00 53.82  ? 316 ILE   A O     1 
ATOM   2641 C CB    . ILE   C 2 304 ? 173.786 231.484 236.028 1.00 43.65  ? 316 ILE   A CB    1 
ATOM   2642 C CG1   . ILE   C 2 304 ? 174.606 232.664 235.516 1.00 42.97  ? 316 ILE   A CG1   1 
ATOM   2643 C CG2   . ILE   C 2 304 ? 173.667 231.570 237.537 1.00 44.50  ? 316 ILE   A CG2   1 
ATOM   2644 C CD1   . ILE   C 2 304 ? 175.980 232.749 236.125 1.00 43.88  ? 316 ILE   A CD1   1 
ATOM   2645 N N     . ARG   C 2 305 ? 175.022 228.472 237.235 1.00 46.86  ? 317 ARG   A N     1 
ATOM   2646 C CA    . ARG   C 2 305 ? 174.751 227.439 238.218 1.00 47.16  ? 317 ARG   A CA    1 
ATOM   2647 C C     . ARG   C 2 305 ? 174.003 228.037 239.408 1.00 51.15  ? 317 ARG   A C     1 
ATOM   2648 O O     . ARG   C 2 305 ? 174.094 229.240 239.663 1.00 56.95  ? 317 ARG   A O     1 
ATOM   2649 C CB    . ARG   C 2 305 ? 176.056 226.800 238.681 1.00 43.31  ? 317 ARG   A CB    1 
ATOM   2650 C CG    . ARG   C 2 305 ? 177.053 226.614 237.560 1.00 45.66  ? 317 ARG   A CG    1 
ATOM   2651 C CD    . ARG   C 2 305 ? 178.042 225.510 237.862 1.00 40.90  ? 317 ARG   A CD    1 
ATOM   2652 N NE    . ARG   C 2 305 ? 179.321 225.758 237.211 1.00 43.30  ? 317 ARG   A NE    1 
ATOM   2653 C CZ    . ARG   C 2 305 ? 179.967 224.867 236.473 1.00 50.50  ? 317 ARG   A CZ    1 
ATOM   2654 N NH1   . ARG   C 2 305 ? 179.493 223.647 236.293 1.00 54.95  ? 317 ARG   A NH1   1 
ATOM   2655 N NH2   . ARG   C 2 305 ? 181.115 225.210 235.901 1.00 51.05  ? 317 ARG   A NH2   1 
ATOM   2656 N N     . PRO   C 2 306 ? 173.241 227.224 240.139 1.00 49.94  ? 318 PRO   A N     1 
ATOM   2657 C CA    . PRO   C 2 306 ? 172.523 227.748 241.304 1.00 48.98  ? 318 PRO   A CA    1 
ATOM   2658 C C     . PRO   C 2 306 ? 173.483 228.383 242.298 1.00 51.07  ? 318 PRO   A C     1 
ATOM   2659 O O     . PRO   C 2 306 ? 174.562 227.853 242.574 1.00 51.15  ? 318 PRO   A O     1 
ATOM   2660 C CB    . PRO   C 2 306 ? 171.838 226.508 241.890 1.00 53.48  ? 318 PRO   A CB    1 
ATOM   2661 C CG    . PRO   C 2 306 ? 172.563 225.344 241.304 1.00 56.29  ? 318 PRO   A CG    1 
ATOM   2662 C CD    . PRO   C 2 306 ? 173.003 225.784 239.950 1.00 54.23  ? 318 PRO   A CD    1 
ATOM   2663 N N     . ASN   C 2 307 ? 173.079 229.535 242.830 1.00 52.85  ? 319 ASN   A N     1 
ATOM   2664 C CA    . ASN   C 2 307 ? 173.910 230.340 243.722 1.00 54.86  ? 319 ASN   A CA    1 
ATOM   2665 C C     . ASN   C 2 307 ? 175.229 230.720 243.047 1.00 51.65  ? 319 ASN   A C     1 
ATOM   2666 O O     . ASN   C 2 307 ? 176.318 230.327 243.467 1.00 51.79  ? 319 ASN   A O     1 
ATOM   2667 C CB    . ASN   C 2 307 ? 174.150 229.620 245.052 1.00 62.88  ? 319 ASN   A CB    1 
ATOM   2668 C CG    . ASN   C 2 307 ? 173.250 230.130 246.155 1.00 71.16  ? 319 ASN   A CG    1 
ATOM   2669 O OD1   . ASN   C 2 307 ? 172.401 230.993 245.928 1.00 59.80  ? 319 ASN   A OD1   1 
ATOM   2670 N ND2   . ASN   C 2 307 ? 173.427 229.598 247.358 1.00 82.93  ? 319 ASN   A ND2   1 
ATOM   2671 N N     . GLU   C 2 308 ? 175.104 231.493 241.970 1.00 48.17  ? 320 GLU   A N     1 
ATOM   2672 C CA    . GLU   C 2 308 ? 176.248 232.071 241.283 1.00 46.87  ? 320 GLU   A CA    1 
ATOM   2673 C C     . GLU   C 2 308 ? 175.893 233.479 240.832 1.00 50.09  ? 320 GLU   A C     1 
ATOM   2674 O O     . GLU   C 2 308 ? 174.721 233.802 240.624 1.00 55.24  ? 320 GLU   A O     1 
ATOM   2675 C CB    . GLU   C 2 308 ? 176.680 231.226 240.081 1.00 46.24  ? 320 GLU   A CB    1 
ATOM   2676 C CG    . GLU   C 2 308 ? 177.624 230.095 240.431 1.00 47.52  ? 320 GLU   A CG    1 
ATOM   2677 C CD    . GLU   C 2 308 ? 178.398 229.602 239.231 1.00 52.64  ? 320 GLU   A CD    1 
ATOM   2678 O OE1   . GLU   C 2 308 ? 178.107 230.063 238.110 1.00 54.66  ? 320 GLU   A OE1   1 
ATOM   2679 O OE2   . GLU   C 2 308 ? 179.299 228.758 239.407 1.00 54.10  ? 320 GLU   A OE2   1 
ATOM   2680 N N     . ASN   C 2 309 ? 176.919 234.315 240.678 1.00 48.27  ? 321 ASN   A N     1 
ATOM   2681 C CA    . ASN   C 2 309 ? 176.721 235.714 240.328 1.00 45.11  ? 321 ASN   A CA    1 
ATOM   2682 C C     . ASN   C 2 309 ? 176.948 235.905 238.839 1.00 46.27  ? 321 ASN   A C     1 
ATOM   2683 O O     . ASN   C 2 309 ? 178.048 235.604 238.350 1.00 47.71  ? 321 ASN   A O     1 
ATOM   2684 C CB    . ASN   C 2 309 ? 177.667 236.604 241.124 1.00 45.89  ? 321 ASN   A CB    1 
ATOM   2685 C CG    . ASN   C 2 309 ? 177.125 238.004 241.316 1.00 48.02  ? 321 ASN   A CG    1 
ATOM   2686 O OD1   . ASN   C 2 309 ? 176.003 238.307 240.914 1.00 50.26  ? 321 ASN   A OD1   1 
ATOM   2687 N ND2   . ASN   C 2 309 ? 177.923 238.866 241.928 1.00 49.94  ? 321 ASN   A ND2   1 
ATOM   2688 N N     . PRO   C 2 310 ? 175.954 236.374 238.083 1.00 46.00  ? 322 PRO   A N     1 
ATOM   2689 C CA    . PRO   C 2 310 ? 176.180 236.619 236.650 1.00 44.78  ? 322 PRO   A CA    1 
ATOM   2690 C C     . PRO   C 2 310 ? 177.251 237.658 236.371 1.00 43.17  ? 322 PRO   A C     1 
ATOM   2691 O O     . PRO   C 2 310 ? 177.928 237.570 235.340 1.00 43.47  ? 322 PRO   A O     1 
ATOM   2692 C CB    . PRO   C 2 310 ? 174.801 237.079 236.152 1.00 45.43  ? 322 PRO   A CB    1 
ATOM   2693 C CG    . PRO   C 2 310 ? 174.075 237.529 237.377 1.00 43.53  ? 322 PRO   A CG    1 
ATOM   2694 C CD    . PRO   C 2 310 ? 174.564 236.651 238.480 1.00 45.05  ? 322 PRO   A CD    1 
ATOM   2695 N N     . ALA   C 2 311 ? 177.418 238.645 237.253 1.00 43.74  ? 323 ALA   A N     1 
ATOM   2696 C CA    . ALA   C 2 311 ? 178.438 239.666 237.039 1.00 42.76  ? 323 ALA   A CA    1 
ATOM   2697 C C     . ALA   C 2 311 ? 179.838 239.070 237.087 1.00 44.86  ? 323 ALA   A C     1 
ATOM   2698 O O     . ALA   C 2 311 ? 180.706 239.436 236.285 1.00 44.73  ? 323 ALA   A O     1 
ATOM   2699 C CB    . ALA   C 2 311 ? 178.291 240.780 238.075 1.00 38.02  ? 323 ALA   A CB    1 
ATOM   2700 N N     . HIS   C 2 312 ? 180.080 238.149 238.021 1.00 46.23  ? 324 HIS   A N     1 
ATOM   2701 C CA    . HIS   C 2 312 ? 181.396 237.525 238.121 1.00 45.35  ? 324 HIS   A CA    1 
ATOM   2702 C C     . HIS   C 2 312 ? 181.696 236.664 236.900 1.00 46.93  ? 324 HIS   A C     1 
ATOM   2703 O O     . HIS   C 2 312 ? 182.816 236.685 236.378 1.00 49.82  ? 324 HIS   A O     1 
ATOM   2704 C CB    . HIS   C 2 312 ? 181.485 236.699 239.402 1.00 43.05  ? 324 HIS   A CB    1 
ATOM   2705 C CG    . HIS   C 2 312 ? 181.477 237.524 240.651 1.00 43.03  ? 324 HIS   A CG    1 
ATOM   2706 N ND1   . HIS   C 2 312 ? 180.970 237.061 241.845 1.00 45.86  ? 324 HIS   A ND1   1 
ATOM   2707 C CD2   . HIS   C 2 312 ? 181.908 238.785 240.887 1.00 41.20  ? 324 HIS   A CD2   1 
ATOM   2708 C CE1   . HIS   C 2 312 ? 181.092 238.000 242.765 1.00 45.35  ? 324 HIS   A CE1   1 
ATOM   2709 N NE2   . HIS   C 2 312 ? 181.658 239.056 242.210 1.00 42.47  ? 324 HIS   A NE2   1 
ATOM   2710 N N     . LYS   C 2 313 ? 180.707 235.904 236.428 1.00 44.42  ? 325 LYS   A N     1 
ATOM   2711 C CA    . LYS   C 2 313 ? 180.913 235.099 235.229 1.00 44.38  ? 325 LYS   A CA    1 
ATOM   2712 C C     . LYS   C 2 313 ? 181.131 235.979 234.005 1.00 46.33  ? 325 LYS   A C     1 
ATOM   2713 O O     . LYS   C 2 313 ? 181.952 235.655 233.140 1.00 49.47  ? 325 LYS   A O     1 
ATOM   2714 C CB    . LYS   C 2 313 ? 179.729 234.157 235.018 1.00 43.07  ? 325 LYS   A CB    1 
ATOM   2715 C CG    . LYS   C 2 313 ? 179.981 233.084 233.974 1.00 43.89  ? 325 LYS   A CG    1 
ATOM   2716 C CD    . LYS   C 2 313 ? 178.831 232.100 233.903 1.00 45.70  ? 325 LYS   A CD    1 
ATOM   2717 C CE    . LYS   C 2 313 ? 179.002 230.976 234.907 1.00 39.37  ? 325 LYS   A CE    1 
ATOM   2718 N NZ    . LYS   C 2 313 ? 180.378 230.425 234.876 1.00 42.20  ? 325 LYS   A NZ    1 
ATOM   2719 N N     . SER   C 2 314 ? 180.405 237.096 233.914 1.00 45.38  ? 326 SER   A N     1 
ATOM   2720 C CA    . SER   C 2 314 ? 180.612 238.019 232.804 1.00 46.18  ? 326 SER   A CA    1 
ATOM   2721 C C     . SER   C 2 314 ? 182.008 238.625 232.849 1.00 45.94  ? 326 SER   A C     1 
ATOM   2722 O O     . SER   C 2 314 ? 182.660 238.776 231.810 1.00 46.50  ? 326 SER   A O     1 
ATOM   2723 C CB    . SER   C 2 314 ? 179.551 239.118 232.823 1.00 48.01  ? 326 SER   A CB    1 
ATOM   2724 O OG    . SER   C 2 314 ? 179.573 239.828 234.045 1.00 52.14  ? 326 SER   A OG    1 
ATOM   2725 N N     . GLN   C 2 315 ? 182.485 238.980 234.044 1.00 45.29  ? 327 GLN   A N     1 
ATOM   2726 C CA    . GLN   C 2 315 ? 183.845 239.491 234.172 1.00 45.66  ? 327 GLN   A CA    1 
ATOM   2727 C C     . GLN   C 2 315 ? 184.867 238.440 233.762 1.00 45.78  ? 327 GLN   A C     1 
ATOM   2728 O O     . GLN   C 2 315 ? 185.852 238.750 233.079 1.00 46.21  ? 327 GLN   A O     1 
ATOM   2729 C CB    . GLN   C 2 315 ? 184.094 239.956 235.607 1.00 42.04  ? 327 GLN   A CB    1 
ATOM   2730 C CG    . GLN   C 2 315 ? 185.555 240.154 235.953 1.00 41.86  ? 327 GLN   A CG    1 
ATOM   2731 C CD    . GLN   C 2 315 ? 185.815 240.051 237.437 1.00 40.48  ? 327 GLN   A CD    1 
ATOM   2732 O OE1   . GLN   C 2 315 ? 185.161 240.715 238.239 1.00 45.41  ? 327 GLN   A OE1   1 
ATOM   2733 N NE2   . GLN   C 2 315 ? 186.780 239.224 237.812 1.00 38.52  ? 327 GLN   A NE2   1 
ATOM   2734 N N     . LEU   C 2 316 ? 184.646 237.189 234.167 1.00 44.17  ? 328 LEU   A N     1 
ATOM   2735 C CA    . LEU   C 2 316 ? 185.545 236.110 233.776 1.00 45.70  ? 328 LEU   A CA    1 
ATOM   2736 C C     . LEU   C 2 316 ? 185.573 235.938 232.263 1.00 46.81  ? 328 LEU   A C     1 
ATOM   2737 O O     . LEU   C 2 316 ? 186.647 235.794 231.664 1.00 48.64  ? 328 LEU   A O     1 
ATOM   2738 C CB    . LEU   C 2 316 ? 185.121 234.810 234.459 1.00 46.10  ? 328 LEU   A CB    1 
ATOM   2739 C CG    . LEU   C 2 316 ? 186.076 233.621 234.389 1.00 47.99  ? 328 LEU   A CG    1 
ATOM   2740 C CD1   . LEU   C 2 316 ? 186.208 232.977 235.754 1.00 44.43  ? 328 LEU   A CD1   1 
ATOM   2741 C CD2   . LEU   C 2 316 ? 185.585 232.611 233.370 1.00 52.05  ? 328 LEU   A CD2   1 
ATOM   2742 N N     . VAL   C 2 317 ? 184.402 235.969 231.624 1.00 46.40  ? 329 VAL   A N     1 
ATOM   2743 C CA    . VAL   C 2 317 ? 184.336 235.803 230.177 1.00 45.03  ? 329 VAL   A CA    1 
ATOM   2744 C C     . VAL   C 2 317 ? 184.991 236.986 229.473 1.00 45.29  ? 329 VAL   A C     1 
ATOM   2745 O O     . VAL   C 2 317 ? 185.655 236.824 228.444 1.00 47.03  ? 329 VAL   A O     1 
ATOM   2746 C CB    . VAL   C 2 317 ? 182.876 235.599 229.731 1.00 45.32  ? 329 VAL   A CB    1 
ATOM   2747 C CG1   . VAL   C 2 317 ? 182.716 235.877 228.247 1.00 45.03  ? 329 VAL   A CG1   1 
ATOM   2748 C CG2   . VAL   C 2 317 ? 182.417 234.191 230.057 1.00 47.68  ? 329 VAL   A CG2   1 
ATOM   2749 N N     . TRP   C 2 318 ? 184.832 238.192 230.022 1.00 45.79  ? 330 TRP   A N     1 
ATOM   2750 C CA    . TRP   C 2 318 ? 185.462 239.371 229.434 1.00 44.33  ? 330 TRP   A CA    1 
ATOM   2751 C C     . TRP   C 2 318 ? 186.983 239.274 229.499 1.00 44.61  ? 330 TRP   A C     1 
ATOM   2752 O O     . TRP   C 2 318 ? 187.679 239.516 228.503 1.00 46.30  ? 330 TRP   A O     1 
ATOM   2753 C CB    . TRP   C 2 318 ? 184.962 240.626 230.152 1.00 42.97  ? 330 TRP   A CB    1 
ATOM   2754 C CG    . TRP   C 2 318 ? 185.493 241.911 229.606 1.00 42.49  ? 330 TRP   A CG    1 
ATOM   2755 C CD1   . TRP   C 2 318 ? 185.005 242.613 228.546 1.00 42.68  ? 330 TRP   A CD1   1 
ATOM   2756 C CD2   . TRP   C 2 318 ? 186.605 242.661 230.107 1.00 42.16  ? 330 TRP   A CD2   1 
ATOM   2757 N NE1   . TRP   C 2 318 ? 185.750 243.749 228.348 1.00 44.67  ? 330 TRP   A NE1   1 
ATOM   2758 C CE2   . TRP   C 2 318 ? 186.738 243.802 229.295 1.00 43.62  ? 330 TRP   A CE2   1 
ATOM   2759 C CE3   . TRP   C 2 318 ? 187.503 242.475 231.161 1.00 42.26  ? 330 TRP   A CE3   1 
ATOM   2760 C CZ2   . TRP   C 2 318 ? 187.732 244.751 229.502 1.00 43.87  ? 330 TRP   A CZ2   1 
ATOM   2761 C CZ3   . TRP   C 2 318 ? 188.488 243.419 231.365 1.00 40.93  ? 330 TRP   A CZ3   1 
ATOM   2762 C CH2   . TRP   C 2 318 ? 188.594 244.542 230.540 1.00 41.19  ? 330 TRP   A CH2   1 
ATOM   2763 N N     . MET   C 2 319 ? 187.518 238.916 230.670 1.00 44.34  ? 331 MET   A N     1 
ATOM   2764 C CA    . MET   C 2 319 ? 188.963 238.759 230.796 1.00 44.96  ? 331 MET   A CA    1 
ATOM   2765 C C     . MET   C 2 319 ? 189.483 237.631 229.916 1.00 43.67  ? 331 MET   A C     1 
ATOM   2766 O O     . MET   C 2 319 ? 190.600 237.716 229.396 1.00 44.25  ? 331 MET   A O     1 
ATOM   2767 C CB    . MET   C 2 319 ? 189.354 238.514 232.255 1.00 42.66  ? 331 MET   A CB    1 
ATOM   2768 C CG    . MET   C 2 319 ? 188.851 239.564 233.223 1.00 41.60  ? 331 MET   A CG    1 
ATOM   2769 S SD    . MET   C 2 319 ? 189.271 239.196 234.934 1.00 52.54  ? 331 MET   A SD    1 
ATOM   2770 C CE    . MET   C 2 319 ? 190.697 238.140 234.713 1.00 47.13  ? 331 MET   A CE    1 
ATOM   2771 N N     . ALA   C 2 320 ? 188.698 236.567 229.744 1.00 44.93  ? 332 ALA   A N     1 
ATOM   2772 C CA    . ALA   C 2 320 ? 189.081 235.514 228.812 1.00 46.02  ? 332 ALA   A CA    1 
ATOM   2773 C C     . ALA   C 2 320 ? 189.111 236.029 227.380 1.00 44.32  ? 332 ALA   A C     1 
ATOM   2774 O O     . ALA   C 2 320 ? 190.016 235.698 226.608 1.00 43.51  ? 332 ALA   A O     1 
ATOM   2775 C CB    . ALA   C 2 320 ? 188.118 234.336 228.935 1.00 47.95  ? 332 ALA   A CB    1 
ATOM   2776 N N     . CYS   C 2 321 ? 188.120 236.839 227.007 1.00 46.62  ? 333 CYS   A N     1 
ATOM   2777 C CA    . CYS   C 2 321 ? 188.054 237.364 225.649 1.00 44.16  ? 333 CYS   A CA    1 
ATOM   2778 C C     . CYS   C 2 321 ? 189.239 238.270 225.351 1.00 45.74  ? 333 CYS   A C     1 
ATOM   2779 O O     . CYS   C 2 321 ? 189.799 238.229 224.250 1.00 44.83  ? 333 CYS   A O     1 
ATOM   2780 C CB    . CYS   C 2 321 ? 186.740 238.117 225.444 1.00 42.44  ? 333 CYS   A CB    1 
ATOM   2781 S SG    . CYS   C 2 321 ? 185.295 237.057 225.236 1.00 60.67  ? 333 CYS   A SG    1 
ATOM   2782 N N     . HIS   C 2 322 ? 189.638 239.096 226.317 1.00 50.21  ? 334 HIS   A N     1 
ATOM   2783 C CA    . HIS   C 2 322 ? 190.712 240.054 226.104 1.00 46.29  ? 334 HIS   A CA    1 
ATOM   2784 C C     . HIS   C 2 322 ? 192.050 239.583 226.662 1.00 45.89  ? 334 HIS   A C     1 
ATOM   2785 O O     . HIS   C 2 322 ? 193.012 240.357 226.664 1.00 47.70  ? 334 HIS   A O     1 
ATOM   2786 C CB    . HIS   C 2 322 ? 190.336 241.406 226.707 1.00 43.76  ? 334 HIS   A CB    1 
ATOM   2787 C CG    . HIS   C 2 322 ? 189.210 242.082 225.993 1.00 43.10  ? 334 HIS   A CG    1 
ATOM   2788 N ND1   . HIS   C 2 322 ? 189.308 242.511 224.688 1.00 44.02  ? 334 HIS   A ND1   1 
ATOM   2789 C CD2   . HIS   C 2 322 ? 187.958 242.399 226.399 1.00 43.94  ? 334 HIS   A CD2   1 
ATOM   2790 C CE1   . HIS   C 2 322 ? 188.166 243.062 224.320 1.00 45.04  ? 334 HIS   A CE1   1 
ATOM   2791 N NE2   . HIS   C 2 322 ? 187.330 243.008 225.341 1.00 43.61  ? 334 HIS   A NE2   1 
ATOM   2792 N N     . SER   C 2 323 ? 192.132 238.334 227.122 1.00 46.05  ? 335 SER   A N     1 
ATOM   2793 C CA    . SER   C 2 323 ? 193.369 237.753 227.650 1.00 44.71  ? 335 SER   A CA    1 
ATOM   2794 C C     . SER   C 2 323 ? 193.950 238.598 228.781 1.00 46.18  ? 335 SER   A C     1 
ATOM   2795 O O     . SER   C 2 323 ? 195.164 238.785 228.881 1.00 48.08  ? 335 SER   A O     1 
ATOM   2796 C CB    . SER   C 2 323 ? 194.402 237.547 226.541 1.00 45.61  ? 335 SER   A CB    1 
ATOM   2797 O OG    . SER   C 2 323 ? 194.938 238.783 226.108 1.00 56.01  ? 335 SER   A OG    1 
ATOM   2798 N N     . ALA   C 2 324 ? 193.077 239.106 229.649 1.00 45.26  ? 336 ALA   A N     1 
ATOM   2799 C CA    . ALA   C 2 324 ? 193.478 239.922 230.787 1.00 44.04  ? 336 ALA   A CA    1 
ATOM   2800 C C     . ALA   C 2 324 ? 193.547 239.117 232.079 1.00 45.60  ? 336 ALA   A C     1 
ATOM   2801 O O     . ALA   C 2 324 ? 193.324 239.662 233.165 1.00 48.73  ? 336 ALA   A O     1 
ATOM   2802 C CB    . ALA   C 2 324 ? 192.527 241.107 230.948 1.00 44.88  ? 336 ALA   A CB    1 
ATOM   2803 N N     . ALA   C 2 325 ? 193.846 237.820 231.980 1.00 44.96  ? 337 ALA   A N     1 
ATOM   2804 C CA    . ALA   C 2 325 ? 193.896 236.970 233.164 1.00 46.07  ? 337 ALA   A CA    1 
ATOM   2805 C C     . ALA   C 2 325 ? 195.017 237.392 234.106 1.00 49.33  ? 337 ALA   A C     1 
ATOM   2806 O O     . ALA   C 2 325 ? 194.829 237.443 235.326 1.00 53.01  ? 337 ALA   A O     1 
ATOM   2807 C CB    . ALA   C 2 325 ? 194.066 235.509 232.749 1.00 46.54  ? 337 ALA   A CB    1 
ATOM   2808 N N     . PHE   C 2 326 ? 196.190 237.689 233.559 1.00 46.71  ? 338 PHE   A N     1 
ATOM   2809 C CA    . PHE   C 2 326 ? 197.353 238.054 234.354 1.00 47.71  ? 338 PHE   A CA    1 
ATOM   2810 C C     . PHE   C 2 326 ? 197.607 239.555 234.377 1.00 50.20  ? 338 PHE   A C     1 
ATOM   2811 O O     . PHE   C 2 326 ? 198.660 239.989 234.855 1.00 53.72  ? 338 PHE   A O     1 
ATOM   2812 C CB    . PHE   C 2 326 ? 198.586 237.320 233.831 1.00 46.02  ? 338 PHE   A CB    1 
ATOM   2813 C CG    . PHE   C 2 326 ? 198.362 235.854 233.626 1.00 47.87  ? 338 PHE   A CG    1 
ATOM   2814 C CD1   . PHE   C 2 326 ? 198.041 235.038 234.692 1.00 48.70  ? 338 PHE   A CD1   1 
ATOM   2815 C CD2   . PHE   C 2 326 ? 198.456 235.295 232.366 1.00 47.24  ? 338 PHE   A CD2   1 
ATOM   2816 C CE1   . PHE   C 2 326 ? 197.827 233.691 234.510 1.00 47.19  ? 338 PHE   A CE1   1 
ATOM   2817 C CE2   . PHE   C 2 326 ? 198.244 233.948 232.178 1.00 48.07  ? 338 PHE   A CE2   1 
ATOM   2818 C CZ    . PHE   C 2 326 ? 197.929 233.145 233.250 1.00 46.95  ? 338 PHE   A CZ    1 
ATOM   2819 N N     . GLU   C 2 327 ? 196.674 240.352 233.869 1.00 50.71  ? 339 GLU   A N     1 
ATOM   2820 C CA    . GLU   C 2 327 ? 196.871 241.790 233.785 1.00 50.55  ? 339 GLU   A CA    1 
ATOM   2821 C C     . GLU   C 2 327 ? 196.649 242.455 235.140 1.00 49.24  ? 339 GLU   A C     1 
ATOM   2822 O O     . GLU   C 2 327 ? 195.969 241.918 236.018 1.00 51.68  ? 339 GLU   A O     1 
ATOM   2823 C CB    . GLU   C 2 327 ? 195.930 242.380 232.732 1.00 51.15  ? 339 GLU   A CB    1 
ATOM   2824 C CG    . GLU   C 2 327 ? 195.942 243.896 232.595 1.00 46.10  ? 339 GLU   A CG    1 
ATOM   2825 C CD    . GLU   C 2 327 ? 197.217 244.417 231.963 1.00 54.86  ? 339 GLU   A CD    1 
ATOM   2826 O OE1   . GLU   C 2 327 ? 198.062 243.600 231.555 1.00 59.39  ? 339 GLU   A OE1   1 
ATOM   2827 O OE2   . GLU   C 2 327 ? 197.373 245.647 231.861 1.00 55.37  ? 339 GLU   A OE2   1 
ATOM   2828 N N     . ASP   C 2 328 ? 197.260 243.627 235.305 1.00 46.77  ? 340 ASP   A N     1 
ATOM   2829 C CA    . ASP   C 2 328 ? 197.044 244.438 236.491 1.00 44.84  ? 340 ASP   A CA    1 
ATOM   2830 C C     . ASP   C 2 328 ? 195.558 244.724 236.664 1.00 45.37  ? 340 ASP   A C     1 
ATOM   2831 O O     . ASP   C 2 328 ? 194.860 245.075 235.710 1.00 48.54  ? 340 ASP   A O     1 
ATOM   2832 C CB    . ASP   C 2 328 ? 197.837 245.742 236.374 1.00 43.33  ? 340 ASP   A CB    1 
ATOM   2833 C CG    . ASP   C 2 328 ? 197.912 246.504 237.679 1.00 44.92  ? 340 ASP   A CG    1 
ATOM   2834 O OD1   . ASP   C 2 328 ? 197.298 246.063 238.669 1.00 55.55  ? 340 ASP   A OD1   1 
ATOM   2835 O OD2   . ASP   C 2 328 ? 198.601 247.546 237.715 1.00 38.18  ? 340 ASP   A OD2   1 
ATOM   2836 N N     . LEU   C 2 329 ? 195.071 244.552 237.892 1.00 47.32  ? 341 LEU   A N     1 
ATOM   2837 C CA    . LEU   C 2 329 ? 193.640 244.683 238.147 1.00 45.32  ? 341 LEU   A CA    1 
ATOM   2838 C C     . LEU   C 2 329 ? 193.177 246.128 238.029 1.00 43.31  ? 341 LEU   A C     1 
ATOM   2839 O O     . LEU   C 2 329 ? 192.035 246.379 237.633 1.00 39.91  ? 341 LEU   A O     1 
ATOM   2840 C CB    . LEU   C 2 329 ? 193.305 244.131 239.531 1.00 46.42  ? 341 LEU   A CB    1 
ATOM   2841 C CG    . LEU   C 2 329 ? 192.867 242.669 239.598 1.00 42.60  ? 341 LEU   A CG    1 
ATOM   2842 C CD1   . LEU   C 2 329 ? 191.571 242.465 238.868 1.00 38.97  ? 341 LEU   A CD1   1 
ATOM   2843 C CD2   . LEU   C 2 329 ? 193.931 241.793 238.997 1.00 47.84  ? 341 LEU   A CD2   1 
ATOM   2844 N N     . ARG   C 2 330 ? 194.043 247.081 238.377 1.00 42.26  ? 342 ARG   A N     1 
ATOM   2845 C CA    . ARG   C 2 330 ? 193.662 248.488 238.336 1.00 41.91  ? 342 ARG   A CA    1 
ATOM   2846 C C     . ARG   C 2 330 ? 193.345 248.937 236.915 1.00 43.77  ? 342 ARG   A C     1 
ATOM   2847 O O     . ARG   C 2 330 ? 192.314 249.573 236.672 1.00 45.31  ? 342 ARG   A O     1 
ATOM   2848 C CB    . ARG   C 2 330 ? 194.780 249.339 238.935 1.00 43.30  ? 342 ARG   A CB    1 
ATOM   2849 C CG    . ARG   C 2 330 ? 195.192 248.901 240.329 1.00 42.93  ? 342 ARG   A CG    1 
ATOM   2850 C CD    . ARG   C 2 330 ? 196.302 249.765 240.900 1.00 43.52  ? 342 ARG   A CD    1 
ATOM   2851 N NE    . ARG   C 2 330 ? 197.618 249.249 240.545 1.00 44.11  ? 342 ARG   A NE    1 
ATOM   2852 C CZ    . ARG   C 2 330 ? 198.564 249.953 239.940 1.00 44.86  ? 342 ARG   A CZ    1 
ATOM   2853 N NH1   . ARG   C 2 330 ? 198.393 251.228 239.645 1.00 47.59  ? 342 ARG   A NH1   1 
ATOM   2854 N NH2   . ARG   C 2 330 ? 199.712 249.362 239.629 1.00 44.95  ? 342 ARG   A NH2   1 
ATOM   2855 N N     . VAL   C 2 331 ? 194.214 248.605 235.960 1.00 42.81  ? 343 VAL   A N     1 
ATOM   2856 C CA    . VAL   C 2 331 ? 193.985 249.005 234.575 1.00 43.81  ? 343 VAL   A CA    1 
ATOM   2857 C C     . VAL   C 2 331 ? 192.807 248.241 233.977 1.00 42.59  ? 343 VAL   A C     1 
ATOM   2858 O O     . VAL   C 2 331 ? 192.039 248.789 233.178 1.00 44.52  ? 343 VAL   A O     1 
ATOM   2859 C CB    . VAL   C 2 331 ? 195.274 248.831 233.750 1.00 43.47  ? 343 VAL   A CB    1 
ATOM   2860 C CG1   . VAL   C 2 331 ? 195.757 247.408 233.816 1.00 46.32  ? 343 VAL   A CG1   1 
ATOM   2861 C CG2   . VAL   C 2 331 ? 195.048 249.248 232.306 1.00 46.39  ? 343 VAL   A CG2   1 
ATOM   2862 N N     . SER   C 2 332 ? 192.640 246.969 234.350 1.00 40.80  ? 344 SER   A N     1 
ATOM   2863 C CA    . SER   C 2 332 ? 191.486 246.213 233.872 1.00 39.67  ? 344 SER   A CA    1 
ATOM   2864 C C     . SER   C 2 332 ? 190.183 246.841 234.348 1.00 42.85  ? 344 SER   A C     1 
ATOM   2865 O O     . SER   C 2 332 ? 189.233 246.989 233.569 1.00 45.22  ? 344 SER   A O     1 
ATOM   2866 C CB    . SER   C 2 332 ? 191.579 244.760 234.335 1.00 43.15  ? 344 SER   A CB    1 
ATOM   2867 O OG    . SER   C 2 332 ? 192.634 244.078 233.680 1.00 45.08  ? 344 SER   A OG    1 
ATOM   2868 N N     . SER   C 2 333 ? 190.125 247.230 235.624 1.00 43.34  ? 345 SER   A N     1 
ATOM   2869 C CA    . SER   C 2 333 ? 188.931 247.878 236.154 1.00 42.37  ? 345 SER   A CA    1 
ATOM   2870 C C     . SER   C 2 333 ? 188.721 249.250 235.525 1.00 44.81  ? 345 SER   A C     1 
ATOM   2871 O O     . SER   C 2 333 ? 187.581 249.663 235.285 1.00 46.67  ? 345 SER   A O     1 
ATOM   2872 C CB    . SER   C 2 333 ? 189.031 247.992 237.674 1.00 41.63  ? 345 SER   A CB    1 
ATOM   2873 O OG    . SER   C 2 333 ? 188.379 249.159 238.140 1.00 51.96  ? 345 SER   A OG    1 
ATOM   2874 N N     . PHE   C 2 334 ? 189.810 249.978 235.268 1.00 44.04  ? 346 PHE   A N     1 
ATOM   2875 C CA    . PHE   C 2 334 ? 189.697 251.280 234.621 1.00 42.82  ? 346 PHE   A CA    1 
ATOM   2876 C C     . PHE   C 2 334 ? 189.125 251.150 233.215 1.00 44.60  ? 346 PHE   A C     1 
ATOM   2877 O O     . PHE   C 2 334 ? 188.244 251.921 232.820 1.00 45.95  ? 346 PHE   A O     1 
ATOM   2878 C CB    . PHE   C 2 334 ? 191.067 251.956 234.585 1.00 44.59  ? 346 PHE   A CB    1 
ATOM   2879 C CG    . PHE   C 2 334 ? 191.073 253.294 233.904 1.00 46.98  ? 346 PHE   A CG    1 
ATOM   2880 C CD1   . PHE   C 2 334 ? 190.622 254.424 234.563 1.00 45.69  ? 346 PHE   A CD1   1 
ATOM   2881 C CD2   . PHE   C 2 334 ? 191.539 253.425 232.609 1.00 48.05  ? 346 PHE   A CD2   1 
ATOM   2882 C CE1   . PHE   C 2 334 ? 190.632 255.654 233.943 1.00 43.64  ? 346 PHE   A CE1   1 
ATOM   2883 C CE2   . PHE   C 2 334 ? 191.549 254.654 231.984 1.00 48.82  ? 346 PHE   A CE2   1 
ATOM   2884 C CZ    . PHE   C 2 334 ? 191.095 255.768 232.652 1.00 47.75  ? 346 PHE   A CZ    1 
ATOM   2885 N N     . ILE   C 2 335 ? 189.610 250.173 232.449 1.00 45.13  ? 347 ILE   A N     1 
ATOM   2886 C CA    . ILE   C 2 335 ? 189.149 249.996 231.076 1.00 46.09  ? 347 ILE   A CA    1 
ATOM   2887 C C     . ILE   C 2 335 ? 187.705 249.513 231.055 1.00 46.67  ? 347 ILE   A C     1 
ATOM   2888 O O     . ILE   C 2 335 ? 186.870 250.029 230.304 1.00 49.77  ? 347 ILE   A O     1 
ATOM   2889 C CB    . ILE   C 2 335 ? 190.078 249.030 230.320 1.00 43.28  ? 347 ILE   A CB    1 
ATOM   2890 C CG1   . ILE   C 2 335 ? 191.448 249.671 230.103 1.00 45.57  ? 347 ILE   A CG1   1 
ATOM   2891 C CG2   . ILE   C 2 335 ? 189.469 248.634 228.989 1.00 42.41  ? 347 ILE   A CG2   1 
ATOM   2892 C CD1   . ILE   C 2 335 ? 192.412 248.794 229.352 1.00 45.53  ? 347 ILE   A CD1   1 
ATOM   2893 N N     . ARG   C 2 336 ? 187.388 248.512 231.880 1.00 44.22  ? 348 ARG   A N     1 
ATOM   2894 C CA    . ARG   C 2 336 ? 186.041 247.954 231.876 1.00 42.75  ? 348 ARG   A CA    1 
ATOM   2895 C C     . ARG   C 2 336 ? 185.019 248.934 232.436 1.00 46.02  ? 348 ARG   A C     1 
ATOM   2896 O O     . ARG   C 2 336 ? 183.865 248.949 231.990 1.00 46.79  ? 348 ARG   A O     1 
ATOM   2897 C CB    . ARG   C 2 336 ? 186.023 246.647 232.667 1.00 41.62  ? 348 ARG   A CB    1 
ATOM   2898 C CG    . ARG   C 2 336 ? 184.679 245.945 232.710 1.00 42.04  ? 348 ARG   A CG    1 
ATOM   2899 C CD    . ARG   C 2 336 ? 184.816 244.554 233.302 1.00 40.82  ? 348 ARG   A CD    1 
ATOM   2900 N NE    . ARG   C 2 336 ? 183.523 243.929 233.551 1.00 39.71  ? 348 ARG   A NE    1 
ATOM   2901 C CZ    . ARG   C 2 336 ? 182.771 243.362 232.619 1.00 42.28  ? 348 ARG   A CZ    1 
ATOM   2902 N NH1   . ARG   C 2 336 ? 183.150 243.325 231.353 1.00 45.53  ? 348 ARG   A NH1   1 
ATOM   2903 N NH2   . ARG   C 2 336 ? 181.609 242.818 232.966 1.00 42.61  ? 348 ARG   A NH2   1 
ATOM   2904 N N     . GLY   C 2 337 ? 185.418 249.765 233.395 1.00 45.73  ? 349 GLY   A N     1 
ATOM   2905 C CA    . GLY   C 2 337 ? 184.509 250.661 234.069 1.00 42.66  ? 349 GLY   A CA    1 
ATOM   2906 C C     . GLY   C 2 337 ? 183.821 250.065 235.274 1.00 44.81  ? 349 GLY   A C     1 
ATOM   2907 O O     . GLY   C 2 337 ? 183.177 250.802 236.030 1.00 49.73  ? 349 GLY   A O     1 
ATOM   2908 N N     . THR   C 2 338 ? 183.940 248.758 235.478 1.00 46.45  ? 350 THR   A N     1 
ATOM   2909 C CA    . THR   C 2 338 ? 183.417 248.073 236.647 1.00 45.03  ? 350 THR   A CA    1 
ATOM   2910 C C     . THR   C 2 338 ? 184.576 247.379 237.341 1.00 45.94  ? 350 THR   A C     1 
ATOM   2911 O O     . THR   C 2 338 ? 185.412 246.753 236.682 1.00 50.91  ? 350 THR   A O     1 
ATOM   2912 C CB    . THR   C 2 338 ? 182.338 247.050 236.266 1.00 43.53  ? 350 THR   A CB    1 
ATOM   2913 O OG1   . THR   C 2 338 ? 181.258 247.717 235.604 1.00 42.10  ? 350 THR   A OG1   1 
ATOM   2914 C CG2   . THR   C 2 338 ? 181.804 246.350 237.502 1.00 45.51  ? 350 THR   A CG2   1 
ATOM   2915 N N     . LYS   C 2 339 ? 184.634 247.502 238.665 1.00 42.56  ? 351 LYS   A N     1 
ATOM   2916 C CA    . LYS   C 2 339 ? 185.757 246.956 239.414 1.00 43.50  ? 351 LYS   A CA    1 
ATOM   2917 C C     . LYS   C 2 339 ? 185.877 245.459 239.173 1.00 43.08  ? 351 LYS   A C     1 
ATOM   2918 O O     . LYS   C 2 339 ? 184.893 244.720 239.264 1.00 43.98  ? 351 LYS   A O     1 
ATOM   2919 C CB    . LYS   C 2 339 ? 185.585 247.250 240.904 1.00 44.40  ? 351 LYS   A CB    1 
ATOM   2920 C CG    . LYS   C 2 339 ? 186.294 246.272 241.818 1.00 46.62  ? 351 LYS   A CG    1 
ATOM   2921 C CD    . LYS   C 2 339 ? 186.505 246.873 243.196 1.00 47.77  ? 351 LYS   A CD    1 
ATOM   2922 C CE    . LYS   C 2 339 ? 187.314 248.155 243.118 1.00 44.72  ? 351 LYS   A CE    1 
ATOM   2923 N NZ    . LYS   C 2 339 ? 187.796 248.583 244.458 1.00 50.92  ? 351 LYS   A NZ    1 
ATOM   2924 N N     . VAL   C 2 340 ? 187.089 245.014 238.858 1.00 42.81  ? 352 VAL   A N     1 
ATOM   2925 C CA    . VAL   C 2 340 ? 187.349 243.624 238.511 1.00 43.46  ? 352 VAL   A CA    1 
ATOM   2926 C C     . VAL   C 2 340 ? 187.825 242.906 239.765 1.00 43.37  ? 352 VAL   A C     1 
ATOM   2927 O O     . VAL   C 2 340 ? 188.845 243.275 240.357 1.00 45.70  ? 352 VAL   A O     1 
ATOM   2928 C CB    . VAL   C 2 340 ? 188.379 243.510 237.376 1.00 42.15  ? 352 VAL   A CB    1 
ATOM   2929 C CG1   . VAL   C 2 340 ? 188.599 242.059 237.009 1.00 40.17  ? 352 VAL   A CG1   1 
ATOM   2930 C CG2   . VAL   C 2 340 ? 187.912 244.295 236.166 1.00 41.37  ? 352 VAL   A CG2   1 
ATOM   2931 N N     . VAL   C 2 341 ? 187.081 241.884 240.169 1.00 43.34  ? 353 VAL   A N     1 
ATOM   2932 C CA    . VAL   C 2 341 ? 187.316 241.174 241.422 1.00 39.58  ? 353 VAL   A CA    1 
ATOM   2933 C C     . VAL   C 2 341 ? 188.314 240.046 241.179 1.00 43.58  ? 353 VAL   A C     1 
ATOM   2934 O O     . VAL   C 2 341 ? 188.200 239.331 240.174 1.00 46.36  ? 353 VAL   A O     1 
ATOM   2935 C CB    . VAL   C 2 341 ? 185.992 240.650 242.000 1.00 39.95  ? 353 VAL   A CB    1 
ATOM   2936 C CG1   . VAL   C 2 341 ? 186.232 239.511 242.960 1.00 42.99  ? 353 VAL   A CG1   1 
ATOM   2937 C CG2   . VAL   C 2 341 ? 185.240 241.776 242.686 1.00 41.96  ? 353 VAL   A CG2   1 
ATOM   2938 N N     . PRO   C 2 342 ? 189.305 239.860 242.051 1.00 43.99  ? 354 PRO   A N     1 
ATOM   2939 C CA    . PRO   C 2 342 ? 190.281 238.782 241.848 1.00 43.41  ? 354 PRO   A CA    1 
ATOM   2940 C C     . PRO   C 2 342 ? 189.619 237.412 241.860 1.00 43.68  ? 354 PRO   A C     1 
ATOM   2941 O O     . PRO   C 2 342 ? 188.439 237.252 242.177 1.00 44.43  ? 354 PRO   A O     1 
ATOM   2942 C CB    . PRO   C 2 342 ? 191.252 238.950 243.023 1.00 40.47  ? 354 PRO   A CB    1 
ATOM   2943 C CG    . PRO   C 2 342 ? 190.523 239.786 244.019 1.00 39.78  ? 354 PRO   A CG    1 
ATOM   2944 C CD    . PRO   C 2 342 ? 189.628 240.682 243.227 1.00 41.80  ? 354 PRO   A CD    1 
ATOM   2945 N N     . ARG   C 2 343 ? 190.414 236.402 241.500 1.00 43.19  ? 355 ARG   A N     1 
ATOM   2946 C CA    . ARG   C 2 343 ? 189.877 235.054 241.331 1.00 43.82  ? 355 ARG   A CA    1 
ATOM   2947 C C     . ARG   C 2 343 ? 189.328 234.503 242.639 1.00 44.55  ? 355 ARG   A C     1 
ATOM   2948 O O     . ARG   C 2 343 ? 188.303 233.812 242.648 1.00 43.40  ? 355 ARG   A O     1 
ATOM   2949 C CB    . ARG   C 2 343 ? 190.954 234.126 240.774 1.00 42.75  ? 355 ARG   A CB    1 
ATOM   2950 C CG    . ARG   C 2 343 ? 190.450 232.739 240.417 1.00 41.58  ? 355 ARG   A CG    1 
ATOM   2951 C CD    . ARG   C 2 343 ? 189.356 232.810 239.369 1.00 42.03  ? 355 ARG   A CD    1 
ATOM   2952 N NE    . ARG   C 2 343 ? 188.914 231.491 238.935 1.00 42.70  ? 355 ARG   A NE    1 
ATOM   2953 C CZ    . ARG   C 2 343 ? 187.888 230.837 239.460 1.00 42.44  ? 355 ARG   A CZ    1 
ATOM   2954 N NH1   . ARG   C 2 343 ? 187.178 231.347 240.451 1.00 41.16  ? 355 ARG   A NH1   1 
ATOM   2955 N NH2   . ARG   C 2 343 ? 187.563 229.642 238.976 1.00 41.56  ? 355 ARG   A NH2   1 
ATOM   2956 N N     . GLY   C 2 344 ? 190.001 234.790 243.754 1.00 48.57  ? 356 GLY   A N     1 
ATOM   2957 C CA    . GLY   C 2 344 ? 189.591 234.221 245.025 1.00 48.70  ? 356 GLY   A CA    1 
ATOM   2958 C C     . GLY   C 2 344 ? 188.196 234.626 245.451 1.00 45.60  ? 356 GLY   A C     1 
ATOM   2959 O O     . GLY   C 2 344 ? 187.518 233.877 246.158 1.00 47.77  ? 356 GLY   A O     1 
ATOM   2960 N N     . LYS   C 2 345 ? 187.742 235.805 245.029 1.00 41.97  ? 357 LYS   A N     1 
ATOM   2961 C CA    . LYS   C 2 345 ? 186.440 236.320 245.434 1.00 40.84  ? 357 LYS   A CA    1 
ATOM   2962 C C     . LYS   C 2 345 ? 185.415 236.259 244.308 1.00 41.58  ? 357 LYS   A C     1 
ATOM   2963 O O     . LYS   C 2 345 ? 184.406 236.968 244.354 1.00 41.80  ? 357 LYS   A O     1 
ATOM   2964 C CB    . LYS   C 2 345 ? 186.577 237.748 245.959 1.00 39.51  ? 357 LYS   A CB    1 
ATOM   2965 C CG    . LYS   C 2 345 ? 187.880 238.012 246.683 1.00 42.49  ? 357 LYS   A CG    1 
ATOM   2966 C CD    . LYS   C 2 345 ? 187.913 239.407 247.263 1.00 44.33  ? 357 LYS   A CD    1 
ATOM   2967 C CE    . LYS   C 2 345 ? 187.393 239.407 248.687 1.00 52.43  ? 357 LYS   A CE    1 
ATOM   2968 N NZ    . LYS   C 2 345 ? 188.235 238.554 249.569 1.00 53.61  ? 357 LYS   A NZ    1 
ATOM   2969 N N     . LEU   C 2 346 ? 185.652 235.427 243.299 1.00 43.45  ? 358 LEU   A N     1 
ATOM   2970 C CA    . LEU   C 2 346 ? 184.688 235.210 242.225 1.00 43.29  ? 358 LEU   A CA    1 
ATOM   2971 C C     . LEU   C 2 346 ? 183.806 234.027 242.606 1.00 45.71  ? 358 LEU   A C     1 
ATOM   2972 O O     . LEU   C 2 346 ? 184.295 232.905 242.764 1.00 48.46  ? 358 LEU   A O     1 
ATOM   2973 C CB    . LEU   C 2 346 ? 185.398 234.958 240.899 1.00 41.58  ? 358 LEU   A CB    1 
ATOM   2974 C CG    . LEU   C 2 346 ? 185.984 236.169 240.177 1.00 41.65  ? 358 LEU   A CG    1 
ATOM   2975 C CD1   . LEU   C 2 346 ? 186.411 235.788 238.772 1.00 42.20  ? 358 LEU   A CD1   1 
ATOM   2976 C CD2   . LEU   C 2 346 ? 184.994 237.315 240.145 1.00 43.49  ? 358 LEU   A CD2   1 
ATOM   2977 N N     . SER   C 2 347 ? 182.509 234.277 242.760 1.00 46.48  ? 359 SER   A N     1 
ATOM   2978 C CA    . SER   C 2 347 ? 181.560 233.224 243.118 1.00 48.98  ? 359 SER   A CA    1 
ATOM   2979 C C     . SER   C 2 347 ? 181.034 232.530 241.860 1.00 51.34  ? 359 SER   A C     1 
ATOM   2980 O O     . SER   C 2 347 ? 179.846 232.553 241.546 1.00 53.90  ? 359 SER   A O     1 
ATOM   2981 C CB    . SER   C 2 347 ? 180.422 233.801 243.951 1.00 48.47  ? 359 SER   A CB    1 
ATOM   2982 O OG    . SER   C 2 347 ? 179.694 234.767 243.217 1.00 54.82  ? 359 SER   A OG    1 
ATOM   2983 N N     . THR   C 2 348 ? 181.958 231.907 241.133 1.00 50.90  ? 360 THR   A N     1 
ATOM   2984 C CA    . THR   C 2 348 ? 181.612 231.204 239.908 1.00 50.00  ? 360 THR   A CA    1 
ATOM   2985 C C     . THR   C 2 348 ? 182.633 230.110 239.643 1.00 51.59  ? 360 THR   A C     1 
ATOM   2986 O O     . THR   C 2 348 ? 183.818 230.254 239.956 1.00 57.86  ? 360 THR   A O     1 
ATOM   2987 C CB    . THR   C 2 348 ? 181.550 232.151 238.705 1.00 51.06  ? 360 THR   A CB    1 
ATOM   2988 O OG1   . THR   C 2 348 ? 181.531 231.385 237.496 1.00 49.05  ? 360 THR   A OG1   1 
ATOM   2989 C CG2   . THR   C 2 348 ? 182.756 233.069 238.693 1.00 52.44  ? 360 THR   A CG2   1 
ATOM   2990 N N     . ARG   C 2 349 ? 182.157 229.011 239.071 1.00 48.86  ? 361 ARG   A N     1 
ATOM   2991 C CA    . ARG   C 2 349 ? 183.017 227.938 238.601 1.00 47.25  ? 361 ARG   A CA    1 
ATOM   2992 C C     . ARG   C 2 349 ? 183.252 228.110 237.101 1.00 46.74  ? 361 ARG   A C     1 
ATOM   2993 O O     . ARG   C 2 349 ? 182.912 229.139 236.513 1.00 48.21  ? 361 ARG   A O     1 
ATOM   2994 C CB    . ARG   C 2 349 ? 182.409 226.585 238.955 1.00 49.24  ? 361 ARG   A CB    1 
ATOM   2995 C CG    . ARG   C 2 349 ? 182.415 226.288 240.444 1.00 46.87  ? 361 ARG   A CG    1 
ATOM   2996 C CD    . ARG   C 2 349 ? 181.443 225.180 240.795 1.00 46.59  ? 361 ARG   A CD    1 
ATOM   2997 N NE    . ARG   C 2 349 ? 181.443 224.118 239.799 1.00 52.10  ? 361 ARG   A NE    1 
ATOM   2998 C CZ    . ARG   C 2 349 ? 182.307 223.114 239.778 1.00 57.31  ? 361 ARG   A CZ    1 
ATOM   2999 N NH1   . ARG   C 2 349 ? 183.262 223.004 240.685 1.00 62.30  ? 361 ARG   A NH1   1 
ATOM   3000 N NH2   . ARG   C 2 349 ? 182.212 222.197 238.820 1.00 53.14  ? 361 ARG   A NH2   1 
ATOM   3001 N N     . GLY   C 2 350 ? 183.841 227.102 236.464 1.00 47.08  ? 362 GLY   A N     1 
ATOM   3002 C CA    . GLY   C 2 350 ? 184.168 227.211 235.059 1.00 46.23  ? 362 GLY   A CA    1 
ATOM   3003 C C     . GLY   C 2 350 ? 182.942 227.338 234.175 1.00 44.45  ? 362 GLY   A C     1 
ATOM   3004 O O     . GLY   C 2 350 ? 181.821 226.997 234.551 1.00 46.53  ? 362 GLY   A O     1 
ATOM   3005 N N     . VAL   C 2 351 ? 183.174 227.858 232.969 1.00 41.91  ? 363 VAL   A N     1 
ATOM   3006 C CA    . VAL   C 2 351 ? 182.083 228.058 232.019 1.00 42.72  ? 363 VAL   A CA    1 
ATOM   3007 C C     . VAL   C 2 351 ? 181.523 226.720 231.554 1.00 44.09  ? 363 VAL   A C     1 
ATOM   3008 O O     . VAL   C 2 351 ? 180.303 226.545 231.453 1.00 47.89  ? 363 VAL   A O     1 
ATOM   3009 C CB    . VAL   C 2 351 ? 182.564 228.915 230.834 1.00 45.11  ? 363 VAL   A CB    1 
ATOM   3010 C CG1   . VAL   C 2 351 ? 181.495 228.985 229.766 1.00 43.55  ? 363 VAL   A CG1   1 
ATOM   3011 C CG2   . VAL   C 2 351 ? 182.933 230.308 231.306 1.00 45.96  ? 363 VAL   A CG2   1 
ATOM   3012 N N     . GLN   C 2 352 ? 182.396 225.761 231.266 1.00 43.73  ? 364 GLN   A N     1 
ATOM   3013 C CA    . GLN   C 2 352 ? 181.951 224.471 230.762 1.00 44.24  ? 364 GLN   A CA    1 
ATOM   3014 C C     . GLN   C 2 352 ? 181.228 223.689 231.851 1.00 45.02  ? 364 GLN   A C     1 
ATOM   3015 O O     . GLN   C 2 352 ? 181.699 223.595 232.988 1.00 42.07  ? 364 GLN   A O     1 
ATOM   3016 C CB    . GLN   C 2 352 ? 183.140 223.671 230.238 1.00 46.07  ? 364 GLN   A CB    1 
ATOM   3017 C CG    . GLN   C 2 352 ? 183.670 224.172 228.910 1.00 48.53  ? 364 GLN   A CG    1 
ATOM   3018 C CD    . GLN   C 2 352 ? 184.190 223.059 228.031 1.00 58.26  ? 364 GLN   A CD    1 
ATOM   3019 O OE1   . GLN   C 2 352 ? 185.395 222.828 227.952 1.00 64.03  ? 364 GLN   A OE1   1 
ATOM   3020 N NE2   . GLN   C 2 352 ? 183.283 222.361 227.361 1.00 60.57  ? 364 GLN   A NE2   1 
ATOM   3021 N N     . ILE   C 2 353 ? 180.080 223.122 231.494 1.00 46.25  ? 365 ILE   A N     1 
ATOM   3022 C CA    . ILE   C 2 353 ? 179.227 222.404 232.432 1.00 47.19  ? 365 ILE   A CA    1 
ATOM   3023 C C     . ILE   C 2 353 ? 179.541 220.920 232.333 1.00 47.91  ? 365 ILE   A C     1 
ATOM   3024 O O     . ILE   C 2 353 ? 179.561 220.353 231.234 1.00 49.35  ? 365 ILE   A O     1 
ATOM   3025 C CB    . ILE   C 2 353 ? 177.740 222.673 232.148 1.00 45.64  ? 365 ILE   A CB    1 
ATOM   3026 C CG1   . ILE   C 2 353 ? 177.447 224.172 232.201 1.00 42.51  ? 365 ILE   A CG1   1 
ATOM   3027 C CG2   . ILE   C 2 353 ? 176.869 221.935 233.145 1.00 47.26  ? 365 ILE   A CG2   1 
ATOM   3028 C CD1   . ILE   C 2 353 ? 177.613 224.775 233.570 1.00 42.98  ? 365 ILE   A CD1   1 
ATOM   3029 N N     . ALA   C 2 354 ? 179.790 220.294 233.478 1.00 48.65  ? 366 ALA   A N     1 
ATOM   3030 C CA    . ALA   C 2 354 ? 180.144 218.887 233.504 1.00 50.21  ? 366 ALA   A CA    1 
ATOM   3031 C C     . ALA   C 2 354 ? 178.930 218.014 233.201 1.00 51.98  ? 366 ALA   A C     1 
ATOM   3032 O O     . ALA   C 2 354 ? 177.779 218.449 233.285 1.00 54.02  ? 366 ALA   A O     1 
ATOM   3033 C CB    . ALA   C 2 354 ? 180.738 218.509 234.859 1.00 50.92  ? 366 ALA   A CB    1 
ATOM   3034 N N     . SER   C 2 355 ? 179.207 216.762 232.836 1.00 50.04  ? 367 SER   A N     1 
ATOM   3035 C CA    . SER   C 2 355 ? 178.131 215.824 232.537 1.00 52.70  ? 367 SER   A CA    1 
ATOM   3036 C C     . SER   C 2 355 ? 177.318 215.491 233.782 1.00 54.37  ? 367 SER   A C     1 
ATOM   3037 O O     . SER   C 2 355 ? 176.093 215.347 233.707 1.00 56.63  ? 367 SER   A O     1 
ATOM   3038 C CB    . SER   C 2 355 ? 178.703 214.553 231.915 1.00 59.26  ? 367 SER   A CB    1 
ATOM   3039 O OG    . SER   C 2 355 ? 177.870 213.440 232.187 1.00 70.55  ? 367 SER   A OG    1 
ATOM   3040 N N     . ASN   C 2 356 ? 177.977 215.361 234.934 1.00 52.55  ? 368 ASN   A N     1 
ATOM   3041 C CA    . ASN   C 2 356 ? 177.300 214.997 236.180 1.00 55.02  ? 368 ASN   A CA    1 
ATOM   3042 C C     . ASN   C 2 356 ? 176.733 216.237 236.878 1.00 56.70  ? 368 ASN   A C     1 
ATOM   3043 O O     . ASN   C 2 356 ? 177.032 216.538 238.032 1.00 59.05  ? 368 ASN   A O     1 
ATOM   3044 C CB    . ASN   C 2 356 ? 178.254 214.236 237.089 1.00 58.30  ? 368 ASN   A CB    1 
ATOM   3045 C CG    . ASN   C 2 356 ? 179.559 214.968 237.309 1.00 61.81  ? 368 ASN   A CG    1 
ATOM   3046 O OD1   . ASN   C 2 356 ? 179.815 216.001 236.695 1.00 60.93  ? 368 ASN   A OD1   1 
ATOM   3047 N ND2   . ASN   C 2 356 ? 180.395 214.434 238.190 1.00 68.05  ? 368 ASN   A ND2   1 
ATOM   3048 N N     . GLU   C 2 357 ? 175.889 216.958 236.146 1.00 53.67  ? 369 GLU   A N     1 
ATOM   3049 C CA    . GLU   C 2 357 ? 175.219 218.147 236.650 1.00 53.65  ? 369 GLU   A CA    1 
ATOM   3050 C C     . GLU   C 2 357 ? 173.735 218.045 236.334 1.00 60.06  ? 369 GLU   A C     1 
ATOM   3051 O O     . GLU   C 2 357 ? 173.344 217.472 235.313 1.00 67.82  ? 369 GLU   A O     1 
ATOM   3052 C CB    . GLU   C 2 357 ? 175.795 219.426 236.027 1.00 56.06  ? 369 GLU   A CB    1 
ATOM   3053 C CG    . GLU   C 2 357 ? 177.263 219.675 236.335 1.00 58.01  ? 369 GLU   A CG    1 
ATOM   3054 C CD    . GLU   C 2 357 ? 177.481 220.892 237.210 1.00 56.39  ? 369 GLU   A CD    1 
ATOM   3055 O OE1   . GLU   C 2 357 ? 176.481 221.494 237.651 1.00 62.33  ? 369 GLU   A OE1   1 
ATOM   3056 O OE2   . GLU   C 2 357 ? 178.653 221.249 237.451 1.00 47.78  ? 369 GLU   A OE2   1 
ATOM   3057 N N     . ASN   C 2 358 ? 172.905 218.603 237.213 1.00 57.66  ? 370 ASN   A N     1 
ATOM   3058 C CA    . ASN   C 2 358 ? 171.456 218.559 237.028 1.00 56.61  ? 370 ASN   A CA    1 
ATOM   3059 C C     . ASN   C 2 358 ? 171.033 219.793 236.242 1.00 56.15  ? 370 ASN   A C     1 
ATOM   3060 O O     . ASN   C 2 358 ? 171.044 220.911 236.759 1.00 57.69  ? 370 ASN   A O     1 
ATOM   3061 C CB    . ASN   C 2 358 ? 170.734 218.466 238.368 1.00 53.95  ? 370 ASN   A CB    1 
ATOM   3062 C CG    . ASN   C 2 358 ? 171.242 219.468 239.377 1.00 62.96  ? 370 ASN   A CG    1 
ATOM   3063 O OD1   . ASN   C 2 358 ? 172.284 220.092 239.177 1.00 73.31  ? 370 ASN   A OD1   1 
ATOM   3064 N ND2   . ASN   C 2 358 ? 170.508 219.631 240.469 1.00 55.22  ? 370 ASN   A ND2   1 
ATOM   3065 N N     . MET   C 2 359 ? 170.663 219.588 234.978 1.00 56.55  ? 371 MET   A N     1 
ATOM   3066 C CA    . MET   C 2 359 ? 170.231 220.693 234.135 1.00 57.01  ? 371 MET   A CA    1 
ATOM   3067 C C     . MET   C 2 359 ? 168.758 221.005 234.364 1.00 56.65  ? 371 MET   A C     1 
ATOM   3068 O O     . MET   C 2 359 ? 167.978 221.089 233.412 1.00 64.09  ? 371 MET   A O     1 
ATOM   3069 C CB    . MET   C 2 359 ? 170.483 220.372 232.660 1.00 55.19  ? 371 MET   A CB    1 
ATOM   3070 C CG    . MET   C 2 359 ? 171.337 221.395 231.933 1.00 51.37  ? 371 MET   A CG    1 
ATOM   3071 S SD    . MET   C 2 359 ? 173.025 221.449 232.551 1.00 65.52  ? 371 MET   A SD    1 
ATOM   3072 C CE    . MET   C 2 359 ? 173.498 219.737 232.359 1.00 54.52  ? 371 MET   A CE    1 
ATOM   3073 N N     . GLU   C 2 360 ? 168.370 221.175 235.625 1.00 51.51  ? 372 GLU   A N     1 
ATOM   3074 C CA    . GLU   C 2 360 ? 167.033 221.626 235.968 1.00 53.83  ? 372 GLU   A CA    1 
ATOM   3075 C C     . GLU   C 2 360 ? 167.025 222.696 237.047 1.00 57.23  ? 372 GLU   A C     1 
ATOM   3076 O O     . GLU   C 2 360 ? 166.002 223.367 237.216 1.00 64.62  ? 372 GLU   A O     1 
ATOM   3077 C CB    . GLU   C 2 360 ? 166.158 220.447 236.418 1.00 56.49  ? 372 GLU   A CB    1 
ATOM   3078 C CG    . GLU   C 2 360 ? 166.537 219.863 237.762 1.00 63.20  ? 372 GLU   A CG    1 
ATOM   3079 C CD    . GLU   C 2 360 ? 165.954 218.482 237.971 1.00 73.91  ? 372 GLU   A CD    1 
ATOM   3080 O OE1   . GLU   C 2 360 ? 165.414 217.914 237.001 1.00 71.71  ? 372 GLU   A OE1   1 
ATOM   3081 O OE2   . GLU   C 2 360 ? 166.034 217.966 239.104 1.00 83.76  ? 372 GLU   A OE2   1 
ATOM   3082 N N     . THR   C 2 361 ? 168.124 222.877 237.776 1.00 56.02  ? 373 THR   A N     1 
ATOM   3083 C CA    . THR   C 2 361 ? 168.308 224.021 238.656 1.00 56.03  ? 373 THR   A CA    1 
ATOM   3084 C C     . THR   C 2 361 ? 169.191 225.085 238.022 1.00 57.23  ? 373 THR   A C     1 
ATOM   3085 O O     . THR   C 2 361 ? 169.541 226.066 238.685 1.00 60.70  ? 373 THR   A O     1 
ATOM   3086 C CB    . THR   C 2 361 ? 168.900 223.576 239.995 1.00 55.79  ? 373 THR   A CB    1 
ATOM   3087 O OG1   . THR   C 2 361 ? 170.259 223.166 239.806 1.00 56.65  ? 373 THR   A OG1   1 
ATOM   3088 C CG2   . THR   C 2 361 ? 168.105 222.416 240.568 1.00 57.56  ? 373 THR   A CG2   1 
ATOM   3089 N N     . MET   C 2 362 ? 169.560 224.913 236.757 1.00 56.30  ? 374 MET   A N     1 
ATOM   3090 C CA    . MET   C 2 362 ? 170.436 225.842 236.065 1.00 54.55  ? 374 MET   A CA    1 
ATOM   3091 C C     . MET   C 2 362 ? 169.623 226.845 235.258 1.00 55.07  ? 374 MET   A C     1 
ATOM   3092 O O     . MET   C 2 362 ? 168.596 226.507 234.662 1.00 58.51  ? 374 MET   A O     1 
ATOM   3093 C CB    . MET   C 2 362 ? 171.393 225.088 235.141 1.00 51.86  ? 374 MET   A CB    1 
ATOM   3094 C CG    . MET   C 2 362 ? 172.774 225.702 235.037 1.00 50.99  ? 374 MET   A CG    1 
ATOM   3095 S SD    . MET   C 2 362 ? 174.034 224.488 234.614 1.00 62.55  ? 374 MET   A SD    1 
ATOM   3096 C CE    . MET   C 2 362 ? 174.300 223.714 236.203 1.00 59.31  ? 374 MET   A CE    1 
ATOM   3097 N N     . GLU   C 2 363 ? 170.094 228.088 235.244 1.00 53.53  ? 375 GLU   A N     1 
ATOM   3098 C CA    . GLU   C 2 363 ? 169.439 229.165 234.521 1.00 51.62  ? 375 GLU   A CA    1 
ATOM   3099 C C     . GLU   C 2 363 ? 170.453 229.879 233.641 1.00 49.36  ? 375 GLU   A C     1 
ATOM   3100 O O     . GLU   C 2 363 ? 171.665 229.718 233.795 1.00 50.88  ? 375 GLU   A O     1 
ATOM   3101 C CB    . GLU   C 2 363 ? 168.777 230.171 235.469 1.00 55.06  ? 375 GLU   A CB    1 
ATOM   3102 C CG    . GLU   C 2 363 ? 168.454 229.622 236.840 1.00 62.14  ? 375 GLU   A CG    1 
ATOM   3103 C CD    . GLU   C 2 363 ? 167.996 230.701 237.794 1.00 82.35  ? 375 GLU   A CD    1 
ATOM   3104 O OE1   . GLU   C 2 363 ? 167.553 231.767 237.316 1.00 83.27  ? 375 GLU   A OE1   1 
ATOM   3105 O OE2   . GLU   C 2 363 ? 168.079 230.487 239.022 1.00 95.38  ? 375 GLU   A OE2   1 
ATOM   3106 N N     . SER   C 2 364 ? 169.938 230.673 232.708 1.00 47.59  ? 376 SER   A N     1 
ATOM   3107 C CA    . SER   C 2 364 ? 170.756 231.418 231.765 1.00 48.86  ? 376 SER   A CA    1 
ATOM   3108 C C     . SER   C 2 364 ? 170.732 232.902 232.105 1.00 47.63  ? 376 SER   A C     1 
ATOM   3109 O O     . SER   C 2 364 ? 169.677 233.459 232.421 1.00 47.39  ? 376 SER   A O     1 
ATOM   3110 C CB    . SER   C 2 364 ? 170.266 231.208 230.333 1.00 53.07  ? 376 SER   A CB    1 
ATOM   3111 O OG    . SER   C 2 364 ? 168.953 231.716 230.175 1.00 56.72  ? 376 SER   A OG    1 
ATOM   3112 N N     . SER   C 2 365 ? 171.897 233.539 232.032 1.00 46.56  ? 377 SER   A N     1 
ATOM   3113 C CA    . SER   C 2 365 ? 172.030 234.962 232.305 1.00 47.97  ? 377 SER   A CA    1 
ATOM   3114 C C     . SER   C 2 365 ? 172.776 235.634 231.164 1.00 48.71  ? 377 SER   A C     1 
ATOM   3115 O O     . SER   C 2 365 ? 173.725 235.070 230.614 1.00 50.49  ? 377 SER   A O     1 
ATOM   3116 C CB    . SER   C 2 365 ? 172.769 235.213 233.619 1.00 48.57  ? 377 SER   A CB    1 
ATOM   3117 O OG    . SER   C 2 365 ? 174.167 235.071 233.442 1.00 49.88  ? 377 SER   A OG    1 
ATOM   3118 N N     . THR   C 2 366 ? 172.340 236.839 230.812 1.00 43.46  ? 378 THR   A N     1 
ATOM   3119 C CA    . THR   C 2 366 ? 173.029 237.608 229.788 1.00 44.10  ? 378 THR   A CA    1 
ATOM   3120 C C     . THR   C 2 366 ? 174.356 238.127 230.326 1.00 46.80  ? 378 THR   A C     1 
ATOM   3121 O O     . THR   C 2 366 ? 174.435 238.640 231.444 1.00 48.85  ? 378 THR   A O     1 
ATOM   3122 C CB    . THR   C 2 366 ? 172.160 238.774 229.322 1.00 45.71  ? 378 THR   A CB    1 
ATOM   3123 O OG1   . THR   C 2 366 ? 170.820 238.316 229.118 1.00 51.32  ? 378 THR   A OG1   1 
ATOM   3124 C CG2   . THR   C 2 366 ? 172.694 239.342 228.020 1.00 48.26  ? 378 THR   A CG2   1 
ATOM   3125 N N     . LEU   C 2 367 ? 175.404 237.989 229.520 1.00 48.74  ? 379 LEU   A N     1 
ATOM   3126 C CA    . LEU   C 2 367 ? 176.741 238.405 229.917 1.00 47.23  ? 379 LEU   A CA    1 
ATOM   3127 C C     . LEU   C 2 367 ? 176.964 239.858 229.526 1.00 47.44  ? 379 LEU   A C     1 
ATOM   3128 O O     . LEU   C 2 367 ? 176.684 240.251 228.389 1.00 47.30  ? 379 LEU   A O     1 
ATOM   3129 C CB    . LEU   C 2 367 ? 177.800 237.517 229.266 1.00 45.45  ? 379 LEU   A CB    1 
ATOM   3130 C CG    . LEU   C 2 367 ? 177.796 236.042 229.658 1.00 46.18  ? 379 LEU   A CG    1 
ATOM   3131 C CD1   . LEU   C 2 367 ? 178.807 235.277 228.827 1.00 46.49  ? 379 LEU   A CD1   1 
ATOM   3132 C CD2   . LEU   C 2 367 ? 178.084 235.882 231.136 1.00 46.98  ? 379 LEU   A CD2   1 
ATOM   3133 N N     . GLU   C 2 368 ? 177.470 240.654 230.468 1.00 46.32  ? 380 GLU   A N     1 
ATOM   3134 C CA    . GLU   C 2 368 ? 177.752 242.063 230.209 1.00 48.50  ? 380 GLU   A CA    1 
ATOM   3135 C C     . GLU   C 2 368 ? 179.183 242.185 229.698 1.00 48.77  ? 380 GLU   A C     1 
ATOM   3136 O O     . GLU   C 2 368 ? 180.135 242.427 230.442 1.00 47.85  ? 380 GLU   A O     1 
ATOM   3137 C CB    . GLU   C 2 368 ? 177.520 242.900 231.459 1.00 50.72  ? 380 GLU   A CB    1 
ATOM   3138 C CG    . GLU   C 2 368 ? 177.729 244.386 231.245 1.00 48.94  ? 380 GLU   A CG    1 
ATOM   3139 C CD    . GLU   C 2 368 ? 176.483 245.076 230.737 1.00 53.42  ? 380 GLU   A CD    1 
ATOM   3140 O OE1   . GLU   C 2 368 ? 175.500 244.376 230.418 1.00 49.95  ? 380 GLU   A OE1   1 
ATOM   3141 O OE2   . GLU   C 2 368 ? 176.487 246.322 230.653 1.00 61.84  ? 380 GLU   A OE2   1 
ATOM   3142 N N     . LEU   C 2 369 ? 179.330 241.990 228.392 1.00 48.99  ? 381 LEU   A N     1 
ATOM   3143 C CA    . LEU   C 2 369 ? 180.620 242.144 227.723 1.00 46.61  ? 381 LEU   A CA    1 
ATOM   3144 C C     . LEU   C 2 369 ? 180.789 243.552 227.161 1.00 49.24  ? 381 LEU   A C     1 
ATOM   3145 O O     . LEU   C 2 369 ? 181.098 243.748 225.988 1.00 47.65  ? 381 LEU   A O     1 
ATOM   3146 C CB    . LEU   C 2 369 ? 180.765 241.093 226.632 1.00 46.12  ? 381 LEU   A CB    1 
ATOM   3147 C CG    . LEU   C 2 369 ? 180.694 239.648 227.120 1.00 47.84  ? 381 LEU   A CG    1 
ATOM   3148 C CD1   . LEU   C 2 369 ? 180.857 238.681 225.963 1.00 48.35  ? 381 LEU   A CD1   1 
ATOM   3149 C CD2   . LEU   C 2 369 ? 181.750 239.405 228.181 1.00 47.19  ? 381 LEU   A CD2   1 
ATOM   3150 N N     . ARG   C 2 370 ? 180.589 244.548 228.016 1.00 52.93  ? 382 ARG   A N     1 
ATOM   3151 C CA    . ARG   C 2 370 ? 180.723 245.948 227.647 1.00 48.48  ? 382 ARG   A CA    1 
ATOM   3152 C C     . ARG   C 2 370 ? 181.843 246.582 228.455 1.00 45.92  ? 382 ARG   A C     1 
ATOM   3153 O O     . ARG   C 2 370 ? 181.985 246.317 229.652 1.00 45.85  ? 382 ARG   A O     1 
ATOM   3154 C CB    . ARG   C 2 370 ? 179.421 246.716 227.879 1.00 48.65  ? 382 ARG   A CB    1 
ATOM   3155 C CG    . ARG   C 2 370 ? 178.383 246.528 226.794 1.00 45.76  ? 382 ARG   A CG    1 
ATOM   3156 C CD    . ARG   C 2 370 ? 177.093 247.244 227.149 1.00 44.33  ? 382 ARG   A CD    1 
ATOM   3157 N NE    . ARG   C 2 370 ? 176.235 247.439 225.988 1.00 50.08  ? 382 ARG   A NE    1 
ATOM   3158 C CZ    . ARG   C 2 370 ? 175.533 246.478 225.402 1.00 64.80  ? 382 ARG   A CZ    1 
ATOM   3159 N NH1   . ARG   C 2 370 ? 175.553 245.234 225.851 1.00 68.01  ? 382 ARG   A NH1   1 
ATOM   3160 N NH2   . ARG   C 2 370 ? 174.791 246.774 224.339 1.00 69.37  ? 382 ARG   A NH2   1 
ATOM   3161 N N     . SER   C 2 371 ? 182.634 247.418 227.794 1.00 45.18  ? 383 SER   A N     1 
ATOM   3162 C CA    . SER   C 2 371 ? 183.732 248.130 228.427 1.00 47.94  ? 383 SER   A CA    1 
ATOM   3163 C C     . SER   C 2 371 ? 183.550 249.626 228.228 1.00 45.83  ? 383 SER   A C     1 
ATOM   3164 O O     . SER   C 2 371 ? 183.146 250.075 227.152 1.00 46.08  ? 383 SER   A O     1 
ATOM   3165 C CB    . SER   C 2 371 ? 185.080 247.677 227.862 1.00 44.89  ? 383 SER   A CB    1 
ATOM   3166 O OG    . SER   C 2 371 ? 185.004 247.498 226.460 1.00 45.31  ? 383 SER   A OG    1 
ATOM   3167 N N     . ARG   C 2 372 ? 183.833 250.392 229.280 1.00 44.63  ? 384 ARG   A N     1 
ATOM   3168 C CA    . ARG   C 2 372 ? 183.679 251.840 229.205 1.00 47.19  ? 384 ARG   A CA    1 
ATOM   3169 C C     . ARG   C 2 372 ? 184.690 252.454 228.241 1.00 49.57  ? 384 ARG   A C     1 
ATOM   3170 O O     . ARG   C 2 372 ? 184.350 253.359 227.470 1.00 54.22  ? 384 ARG   A O     1 
ATOM   3171 C CB    . ARG   C 2 372 ? 183.811 252.444 230.602 1.00 46.39  ? 384 ARG   A CB    1 
ATOM   3172 C CG    . ARG   C 2 372 ? 184.226 253.895 230.627 1.00 47.19  ? 384 ARG   A CG    1 
ATOM   3173 C CD    . ARG   C 2 372 ? 183.035 254.808 230.420 1.00 47.92  ? 384 ARG   A CD    1 
ATOM   3174 N NE    . ARG   C 2 372 ? 183.443 256.177 230.134 1.00 61.73  ? 384 ARG   A NE    1 
ATOM   3175 C CZ    . ARG   C 2 372 ? 183.995 256.997 231.019 1.00 66.88  ? 384 ARG   A CZ    1 
ATOM   3176 N NH1   . ARG   C 2 372 ? 184.194 256.629 232.274 1.00 65.39  ? 384 ARG   A NH1   1 
ATOM   3177 N NH2   . ARG   C 2 372 ? 184.358 258.217 230.633 1.00 69.27  ? 384 ARG   A NH2   1 
ATOM   3178 N N     . TYR   C 2 373 ? 185.927 251.975 228.264 1.00 45.07  ? 385 TYR   A N     1 
ATOM   3179 C CA    . TYR   C 2 373 ? 186.975 252.418 227.355 1.00 45.12  ? 385 TYR   A CA    1 
ATOM   3180 C C     . TYR   C 2 373 ? 187.496 251.229 226.551 1.00 49.40  ? 385 TYR   A C     1 
ATOM   3181 O O     . TYR   C 2 373 ? 187.077 250.086 226.746 1.00 53.02  ? 385 TYR   A O     1 
ATOM   3182 C CB    . TYR   C 2 373 ? 188.123 253.081 228.119 1.00 47.13  ? 385 TYR   A CB    1 
ATOM   3183 C CG    . TYR   C 2 373 ? 187.777 254.358 228.844 1.00 49.54  ? 385 TYR   A CG    1 
ATOM   3184 C CD1   . TYR   C 2 373 ? 187.578 255.541 228.149 1.00 55.29  ? 385 TYR   A CD1   1 
ATOM   3185 C CD2   . TYR   C 2 373 ? 187.698 254.393 230.227 1.00 49.36  ? 385 TYR   A CD2   1 
ATOM   3186 C CE1   . TYR   C 2 373 ? 187.276 256.713 228.809 1.00 56.79  ? 385 TYR   A CE1   1 
ATOM   3187 C CE2   . TYR   C 2 373 ? 187.399 255.564 230.895 1.00 52.04  ? 385 TYR   A CE2   1 
ATOM   3188 C CZ    . TYR   C 2 373 ? 187.189 256.720 230.179 1.00 54.12  ? 385 TYR   A CZ    1 
ATOM   3189 O OH    . TYR   C 2 373 ? 186.889 257.891 230.835 1.00 56.14  ? 385 TYR   A OH    1 
ATOM   3190 N N     . TRP   C 2 374 ? 188.424 251.508 225.638 1.00 48.45  ? 386 TRP   A N     1 
ATOM   3191 C CA    . TRP   C 2 374 ? 189.116 250.465 224.896 1.00 44.45  ? 386 TRP   A CA    1 
ATOM   3192 C C     . TRP   C 2 374 ? 190.584 250.841 224.758 1.00 44.82  ? 386 TRP   A C     1 
ATOM   3193 O O     . TRP   C 2 374 ? 190.940 252.021 224.750 1.00 49.77  ? 386 TRP   A O     1 
ATOM   3194 C CB    . TRP   C 2 374 ? 188.493 250.227 223.511 1.00 43.76  ? 386 TRP   A CB    1 
ATOM   3195 C CG    . TRP   C 2 374 ? 188.884 251.221 222.457 1.00 43.24  ? 386 TRP   A CG    1 
ATOM   3196 C CD1   . TRP   C 2 374 ? 188.248 252.387 222.157 1.00 45.70  ? 386 TRP   A CD1   1 
ATOM   3197 C CD2   . TRP   C 2 374 ? 189.985 251.120 221.545 1.00 44.01  ? 386 TRP   A CD2   1 
ATOM   3198 N NE1   . TRP   C 2 374 ? 188.889 253.026 221.123 1.00 45.42  ? 386 TRP   A NE1   1 
ATOM   3199 C CE2   . TRP   C 2 374 ? 189.959 252.268 220.729 1.00 43.48  ? 386 TRP   A CE2   1 
ATOM   3200 C CE3   . TRP   C 2 374 ? 190.994 250.175 221.343 1.00 47.28  ? 386 TRP   A CE3   1 
ATOM   3201 C CZ2   . TRP   C 2 374 ? 190.902 252.495 219.731 1.00 43.72  ? 386 TRP   A CZ2   1 
ATOM   3202 C CZ3   . TRP   C 2 374 ? 191.928 250.403 220.350 1.00 45.41  ? 386 TRP   A CZ3   1 
ATOM   3203 C CH2   . TRP   C 2 374 ? 191.875 251.552 219.558 1.00 42.25  ? 386 TRP   A CH2   1 
ATOM   3204 N N     . ALA   C 2 375 ? 191.432 249.823 224.644 1.00 43.98  ? 387 ALA   A N     1 
ATOM   3205 C CA    . ALA   C 2 375 ? 192.870 250.032 224.576 1.00 42.82  ? 387 ALA   A CA    1 
ATOM   3206 C C     . ALA   C 2 375 ? 193.479 249.018 223.621 1.00 44.46  ? 387 ALA   A C     1 
ATOM   3207 O O     . ALA   C 2 375 ? 192.886 247.980 223.322 1.00 47.43  ? 387 ALA   A O     1 
ATOM   3208 C CB    . ALA   C 2 375 ? 193.523 249.924 225.957 1.00 44.28  ? 387 ALA   A CB    1 
ATOM   3209 N N     . ILE   C 2 376 ? 194.675 249.339 223.141 1.00 44.77  ? 388 ILE   A N     1 
ATOM   3210 C CA    . ILE   C 2 376 ? 195.379 248.476 222.199 1.00 44.99  ? 388 ILE   A CA    1 
ATOM   3211 C C     . ILE   C 2 376 ? 196.172 247.435 222.974 1.00 46.46  ? 388 ILE   A C     1 
ATOM   3212 O O     . ILE   C 2 376 ? 196.975 247.773 223.851 1.00 50.58  ? 388 ILE   A O     1 
ATOM   3213 C CB    . ILE   C 2 376 ? 196.296 249.304 221.287 1.00 43.65  ? 388 ILE   A CB    1 
ATOM   3214 C CG1   . ILE   C 2 376 ? 195.470 250.177 220.346 1.00 44.41  ? 388 ILE   A CG1   1 
ATOM   3215 C CG2   . ILE   C 2 376 ? 197.212 248.396 220.491 1.00 42.98  ? 388 ILE   A CG2   1 
ATOM   3216 C CD1   . ILE   C 2 376 ? 196.169 251.445 219.929 1.00 40.44  ? 388 ILE   A CD1   1 
ATOM   3217 N N     . ARG   C 2 377 ? 195.947 246.165 222.658 1.00 44.16  ? 389 ARG   A N     1 
ATOM   3218 C CA    . ARG   C 2 377 ? 196.734 245.106 223.267 1.00 46.14  ? 389 ARG   A CA    1 
ATOM   3219 C C     . ARG   C 2 377 ? 198.148 245.105 222.705 1.00 49.54  ? 389 ARG   A C     1 
ATOM   3220 O O     . ARG   C 2 377 ? 198.370 245.339 221.515 1.00 52.48  ? 389 ARG   A O     1 
ATOM   3221 C CB    . ARG   C 2 377 ? 196.076 243.748 223.047 1.00 44.25  ? 389 ARG   A CB    1 
ATOM   3222 C CG    . ARG   C 2 377 ? 195.064 243.403 224.114 1.00 43.90  ? 389 ARG   A CG    1 
ATOM   3223 C CD    . ARG   C 2 377 ? 193.905 242.614 223.547 1.00 49.54  ? 389 ARG   A CD    1 
ATOM   3224 N NE    . ARG   C 2 377 ? 193.317 243.242 222.368 1.00 49.69  ? 389 ARG   A NE    1 
ATOM   3225 C CZ    . ARG   C 2 377 ? 192.678 244.404 222.369 1.00 46.48  ? 389 ARG   A CZ    1 
ATOM   3226 N NH1   . ARG   C 2 377 ? 192.527 245.111 223.475 1.00 48.83  ? 389 ARG   A NH1   1 
ATOM   3227 N NH2   . ARG   C 2 377 ? 192.171 244.865 221.230 1.00 43.81  ? 389 ARG   A NH2   1 
ATOM   3228 N N     . THR   C 2 378 ? 199.110 244.838 223.579 1.00 49.10  ? 390 THR   A N     1 
ATOM   3229 C CA    . THR   C 2 378 ? 200.520 244.939 223.244 1.00 51.13  ? 390 THR   A CA    1 
ATOM   3230 C C     . THR   C 2 378 ? 201.196 243.586 223.391 1.00 49.89  ? 390 THR   A C     1 
ATOM   3231 O O     . THR   C 2 378 ? 200.843 242.792 224.268 1.00 51.45  ? 390 THR   A O     1 
ATOM   3232 C CB    . THR   C 2 378 ? 201.226 245.972 224.129 1.00 53.26  ? 390 THR   A CB    1 
ATOM   3233 O OG1   . THR   C 2 378 ? 202.636 245.939 223.877 1.00 57.56  ? 390 THR   A OG1   1 
ATOM   3234 C CG2   . THR   C 2 378 ? 200.974 245.686 225.592 1.00 46.62  ? 390 THR   A CG2   1 
ATOM   3235 N N     . ARG   C 2 379 ? 202.163 243.329 222.518 1.00 49.11  ? 391 ARG   A N     1 
ATOM   3236 C CA    . ARG   C 2 379 ? 203.007 242.149 222.594 1.00 47.51  ? 391 ARG   A CA    1 
ATOM   3237 C C     . ARG   C 2 379 ? 204.312 242.418 223.324 1.00 48.16  ? 391 ARG   A C     1 
ATOM   3238 O O     . ARG   C 2 379 ? 205.200 241.561 223.322 1.00 52.60  ? 391 ARG   A O     1 
ATOM   3239 C CB    . ARG   C 2 379 ? 203.297 241.622 221.187 1.00 51.22  ? 391 ARG   A CB    1 
ATOM   3240 C CG    . ARG   C 2 379 ? 204.271 242.477 220.397 1.00 46.02  ? 391 ARG   A CG    1 
ATOM   3241 C CD    . ARG   C 2 379 ? 205.218 241.621 219.581 1.00 47.50  ? 391 ARG   A CD    1 
ATOM   3242 N NE    . ARG   C 2 379 ? 204.501 240.785 218.627 1.00 57.02  ? 391 ARG   A NE    1 
ATOM   3243 C CZ    . ARG   C 2 379 ? 204.213 241.147 217.386 1.00 73.20  ? 391 ARG   A CZ    1 
ATOM   3244 N NH1   . ARG   C 2 379 ? 204.574 242.327 216.908 1.00 69.54  ? 391 ARG   A NH1   1 
ATOM   3245 N NH2   . ARG   C 2 379 ? 203.544 240.305 216.603 1.00 83.02  ? 391 ARG   A NH2   1 
ATOM   3246 N N     . SER   C 2 380 ? 204.444 243.580 223.950 1.00 46.53  ? 392 SER   A N     1 
ATOM   3247 C CA    . SER   C 2 380 ? 205.690 244.022 224.554 1.00 47.99  ? 392 SER   A CA    1 
ATOM   3248 C C     . SER   C 2 380 ? 205.701 243.770 226.057 1.00 48.75  ? 392 SER   A C     1 
ATOM   3249 O O     . SER   C 2 380 ? 204.668 243.524 226.683 1.00 49.16  ? 392 SER   A O     1 
ATOM   3250 C CB    . SER   C 2 380 ? 205.914 245.511 224.281 1.00 46.93  ? 392 SER   A CB    1 
ATOM   3251 O OG    . SER   C 2 380 ? 206.857 246.056 225.184 1.00 51.26  ? 392 SER   A OG    1 
ATOM   3252 N N     . GLY   C 2 381 ? 206.896 243.831 226.626 1.00 49.76  ? 393 GLY   A N     1 
ATOM   3253 C CA    . GLY   C 2 381 ? 207.086 243.835 228.061 1.00 46.33  ? 393 GLY   A CA    1 
ATOM   3254 C C     . GLY   C 2 381 ? 206.955 245.232 228.622 1.00 53.09  ? 393 GLY   A C     1 
ATOM   3255 O O     . GLY   C 2 381 ? 206.069 246.001 228.237 1.00 62.17  ? 393 GLY   A O     1 
ATOM   3256 N N     . GLY   C 2 382 ? 207.851 245.577 229.539 1.00 51.46  ? 394 GLY   A N     1 
ATOM   3257 C CA    . GLY   C 2 382 ? 207.839 246.912 230.103 1.00 59.15  ? 394 GLY   A CA    1 
ATOM   3258 C C     . GLY   C 2 382 ? 209.085 247.714 229.796 1.00 63.61  ? 394 GLY   A C     1 
ATOM   3259 O O     . GLY   C 2 382 ? 209.561 247.727 228.657 1.00 62.04  ? 394 GLY   A O     1 
ATOM   3260 N N     . ASN   C 2 383 ? 209.617 248.400 230.806 1.00 68.37  ? 395 ASN   A N     1 
ATOM   3261 C CA    . ASN   C 2 383 ? 210.872 249.139 230.674 1.00 67.18  ? 395 ASN   A CA    1 
ATOM   3262 C C     . ASN   C 2 383 ? 212.027 248.263 231.156 1.00 69.16  ? 395 ASN   A C     1 
ATOM   3263 O O     . ASN   C 2 383 ? 212.603 248.454 232.228 1.00 74.67  ? 395 ASN   A O     1 
ATOM   3264 C CB    . ASN   C 2 383 ? 210.807 250.449 231.448 1.00 72.46  ? 395 ASN   A CB    1 
ATOM   3265 C CG    . ASN   C 2 383 ? 210.284 251.593 230.611 1.00 81.62  ? 395 ASN   A CG    1 
ATOM   3266 O OD1   . ASN   C 2 383 ? 209.794 251.392 229.501 1.00 81.16  ? 395 ASN   A OD1   1 
ATOM   3267 N ND2   . ASN   C 2 383 ? 210.383 252.807 231.140 1.00 87.08  ? 395 ASN   A ND2   1 
ATOM   3268 N N     . THR   C 2 384 ? 212.359 247.276 230.330 1.00 64.18  ? 396 THR   A N     1 
ATOM   3269 C CA    . THR   C 2 384 ? 213.472 246.377 230.624 1.00 67.67  ? 396 THR   A CA    1 
ATOM   3270 C C     . THR   C 2 384 ? 214.822 246.980 230.254 1.00 70.50  ? 396 THR   A C     1 
ATOM   3271 O O     . THR   C 2 384 ? 215.589 246.384 229.493 1.00 72.59  ? 396 THR   A O     1 
ATOM   3272 C CB    . THR   C 2 384 ? 213.255 245.048 229.907 1.00 70.33  ? 396 THR   A CB    1 
ATOM   3273 O OG1   . THR   C 2 384 ? 213.428 245.229 228.497 1.00 75.72  ? 396 THR   A OG1   1 
ATOM   3274 C CG2   . THR   C 2 384 ? 211.853 244.527 230.177 1.00 58.99  ? 396 THR   A CG2   1 
ATOM   3275 N N     . ASN   C 2 385 ? 215.131 248.159 230.782 1.00 72.54  ? 397 ASN   A N     1 
ATOM   3276 C CA    . ASN   C 2 385 ? 216.376 248.847 230.467 1.00 69.92  ? 397 ASN   A CA    1 
ATOM   3277 C C     . ASN   C 2 385 ? 217.449 248.548 231.506 1.00 75.34  ? 397 ASN   A C     1 
ATOM   3278 O O     . ASN   C 2 385 ? 218.381 249.330 231.691 1.00 78.08  ? 397 ASN   A O     1 
ATOM   3279 C CB    . ASN   C 2 385 ? 216.140 250.357 230.372 1.00 65.60  ? 397 ASN   A CB    1 
ATOM   3280 C CG    . ASN   C 2 385 ? 215.766 250.976 231.706 1.00 65.53  ? 397 ASN   A CG    1 
ATOM   3281 O OD1   . ASN   C 2 385 ? 215.170 250.324 232.561 1.00 67.43  ? 397 ASN   A OD1   1 
ATOM   3282 N ND2   . ASN   C 2 385 ? 216.111 252.244 231.886 1.00 54.84  ? 397 ASN   A ND2   1 
ATOM   3283 N N     . THR   C 2 425 ? 228.632 230.787 232.556 1.00 69.29  ? 437 THR   A N     1 
ATOM   3284 C CA    . THR   C 2 425 ? 227.229 231.117 232.778 1.00 76.52  ? 437 THR   A CA    1 
ATOM   3285 C C     . THR   C 2 425 ? 227.054 231.909 234.066 1.00 70.61  ? 437 THR   A C     1 
ATOM   3286 O O     . THR   C 2 425 ? 226.012 232.522 234.291 1.00 70.07  ? 437 THR   A O     1 
ATOM   3287 C CB    . THR   C 2 425 ? 226.350 229.853 232.841 1.00 86.90  ? 437 THR   A CB    1 
ATOM   3288 O OG1   . THR   C 2 425 ? 224.968 230.226 232.785 1.00 79.58  ? 437 THR   A OG1   1 
ATOM   3289 C CG2   . THR   C 2 425 ? 226.608 229.081 234.125 1.00 80.37  ? 437 THR   A CG2   1 
ATOM   3290 N N     . SER   C 2 426 ? 228.083 231.884 234.916 1.00 71.67  ? 438 SER   A N     1 
ATOM   3291 C CA    . SER   C 2 426 ? 228.022 232.629 236.168 1.00 73.69  ? 438 SER   A CA    1 
ATOM   3292 C C     . SER   C 2 426 ? 227.964 234.128 235.914 1.00 65.27  ? 438 SER   A C     1 
ATOM   3293 O O     . SER   C 2 426 ? 227.261 234.857 236.624 1.00 62.19  ? 438 SER   A O     1 
ATOM   3294 C CB    . SER   C 2 426 ? 229.223 232.280 237.046 1.00 86.54  ? 438 SER   A CB    1 
ATOM   3295 O OG    . SER   C 2 426 ? 230.389 232.950 236.599 1.00 90.17  ? 438 SER   A OG    1 
ATOM   3296 N N     . ASP   C 2 427 ? 228.705 234.606 234.914 1.00 65.67  ? 439 ASP   A N     1 
ATOM   3297 C CA    . ASP   C 2 427 ? 228.700 236.030 234.597 1.00 64.66  ? 439 ASP   A CA    1 
ATOM   3298 C C     . ASP   C 2 427 ? 227.316 236.488 234.152 1.00 59.33  ? 439 ASP   A C     1 
ATOM   3299 O O     . ASP   C 2 427 ? 226.842 237.555 234.558 1.00 57.84  ? 439 ASP   A O     1 
ATOM   3300 C CB    . ASP   C 2 427 ? 229.746 236.329 233.524 1.00 69.87  ? 439 ASP   A CB    1 
ATOM   3301 C CG    . ASP   C 2 427 ? 231.163 236.216 234.047 1.00 76.17  ? 439 ASP   A CG    1 
ATOM   3302 O OD1   . ASP   C 2 427 ? 231.341 236.188 235.281 1.00 76.42  ? 439 ASP   A OD1   1 
ATOM   3303 O OD2   . ASP   C 2 427 ? 232.100 236.158 233.222 1.00 75.52  ? 439 ASP   A OD2   1 
ATOM   3304 N N     . MET   C 2 428 ? 226.649 235.686 233.320 1.00 59.54  ? 440 MET   A N     1 
ATOM   3305 C CA    . MET   C 2 428 ? 225.305 236.040 232.874 1.00 55.81  ? 440 MET   A CA    1 
ATOM   3306 C C     . MET   C 2 428 ? 224.329 236.064 234.042 1.00 55.69  ? 440 MET   A C     1 
ATOM   3307 O O     . MET   C 2 428 ? 223.474 236.953 234.134 1.00 54.98  ? 440 MET   A O     1 
ATOM   3308 C CB    . MET   C 2 428 ? 224.833 235.062 231.796 1.00 54.90  ? 440 MET   A CB    1 
ATOM   3309 C CG    . MET   C 2 428 ? 225.554 235.137 230.443 1.00 60.17  ? 440 MET   A CG    1 
ATOM   3310 S SD    . MET   C 2 428 ? 225.384 236.652 229.461 1.00 74.19  ? 440 MET   A SD    1 
ATOM   3311 C CE    . MET   C 2 428 ? 226.511 237.801 230.253 1.00 66.02  ? 440 MET   A CE    1 
ATOM   3312 N N     . ARG   C 2 429 ? 224.439 235.091 234.948 1.00 55.80  ? 441 ARG   A N     1 
ATOM   3313 C CA    . ARG   C 2 429 ? 223.557 235.061 236.110 1.00 50.22  ? 441 ARG   A CA    1 
ATOM   3314 C C     . ARG   C 2 429 ? 223.783 236.274 237.002 1.00 50.00  ? 441 ARG   A C     1 
ATOM   3315 O O     . ARG   C 2 429 ? 222.827 236.889 237.484 1.00 49.91  ? 441 ARG   A O     1 
ATOM   3316 C CB    . ARG   C 2 429 ? 223.756 233.766 236.898 1.00 49.36  ? 441 ARG   A CB    1 
ATOM   3317 C CG    . ARG   C 2 429 ? 223.194 232.535 236.209 1.00 53.18  ? 441 ARG   A CG    1 
ATOM   3318 C CD    . ARG   C 2 429 ? 223.540 231.265 236.963 1.00 54.67  ? 441 ARG   A CD    1 
ATOM   3319 N NE    . ARG   C 2 429 ? 222.510 230.906 237.929 1.00 50.29  ? 441 ARG   A NE    1 
ATOM   3320 C CZ    . ARG   C 2 429 ? 221.860 229.750 237.935 1.00 49.58  ? 441 ARG   A CZ    1 
ATOM   3321 N NH1   . ARG   C 2 429 ? 222.109 228.813 237.037 1.00 50.73  ? 441 ARG   A NH1   1 
ATOM   3322 N NH2   . ARG   C 2 429 ? 220.939 229.529 238.868 1.00 48.03  ? 441 ARG   A NH2   1 
ATOM   3323 N N     . THR   C 2 430 ? 225.048 236.633 237.239 1.00 53.34  ? 442 THR   A N     1 
ATOM   3324 C CA    . THR   C 2 430 ? 225.337 237.808 238.057 1.00 49.16  ? 442 THR   A CA    1 
ATOM   3325 C C     . THR   C 2 430 ? 224.820 239.081 237.396 1.00 48.58  ? 442 THR   A C     1 
ATOM   3326 O O     . THR   C 2 430 ? 224.273 239.961 238.070 1.00 48.10  ? 442 THR   A O     1 
ATOM   3327 C CB    . THR   C 2 430 ? 226.837 237.916 238.325 1.00 51.27  ? 442 THR   A CB    1 
ATOM   3328 O OG1   . THR   C 2 430 ? 227.561 237.633 237.123 1.00 58.98  ? 442 THR   A OG1   1 
ATOM   3329 C CG2   . THR   C 2 430 ? 227.256 236.930 239.401 1.00 49.66  ? 442 THR   A CG2   1 
ATOM   3330 N N     . GLU   C 2 431 ? 224.980 239.193 236.075 1.00 50.41  ? 443 GLU   A N     1 
ATOM   3331 C CA    . GLU   C 2 431 ? 224.471 240.357 235.358 1.00 50.05  ? 443 GLU   A CA    1 
ATOM   3332 C C     . GLU   C 2 431 ? 222.954 240.449 235.454 1.00 48.88  ? 443 GLU   A C     1 
ATOM   3333 O O     . GLU   C 2 431 ? 222.397 241.534 235.660 1.00 48.40  ? 443 GLU   A O     1 
ATOM   3334 C CB    . GLU   C 2 431 ? 224.919 240.297 233.895 1.00 48.35  ? 443 GLU   A CB    1 
ATOM   3335 C CG    . GLU   C 2 431 ? 224.187 241.224 232.920 1.00 53.99  ? 443 GLU   A CG    1 
ATOM   3336 C CD    . GLU   C 2 431 ? 224.359 242.714 233.196 1.00 69.50  ? 443 GLU   A CD    1 
ATOM   3337 O OE1   . GLU   C 2 431 ? 224.625 243.121 234.345 1.00 72.40  ? 443 GLU   A OE1   1 
ATOM   3338 O OE2   . GLU   C 2 431 ? 224.225 243.496 232.232 1.00 75.72  ? 443 GLU   A OE2   1 
ATOM   3339 N N     . ILE   C 2 432 ? 222.266 239.315 235.314 1.00 48.87  ? 444 ILE   A N     1 
ATOM   3340 C CA    . ILE   C 2 432 ? 220.810 239.313 235.395 1.00 45.63  ? 444 ILE   A CA    1 
ATOM   3341 C C     . ILE   C 2 432 ? 220.347 239.642 236.808 1.00 44.83  ? 444 ILE   A C     1 
ATOM   3342 O O     . ILE   C 2 432 ? 219.364 240.365 236.998 1.00 43.79  ? 444 ILE   A O     1 
ATOM   3343 C CB    . ILE   C 2 432 ? 220.261 237.964 234.903 1.00 45.79  ? 444 ILE   A CB    1 
ATOM   3344 C CG1   . ILE   C 2 432 ? 220.283 237.933 233.380 1.00 43.61  ? 444 ILE   A CG1   1 
ATOM   3345 C CG2   . ILE   C 2 432 ? 218.851 237.730 235.411 1.00 48.36  ? 444 ILE   A CG2   1 
ATOM   3346 C CD1   . ILE   C 2 432 ? 219.877 236.630 232.801 1.00 42.09  ? 444 ILE   A CD1   1 
ATOM   3347 N N     . ILE   C 2 433 ? 221.044 239.124 237.822 1.00 45.69  ? 445 ILE   A N     1 
ATOM   3348 C CA    . ILE   C 2 433 ? 220.685 239.439 239.201 1.00 43.56  ? 445 ILE   A CA    1 
ATOM   3349 C C     . ILE   C 2 433 ? 220.889 240.921 239.474 1.00 44.87  ? 445 ILE   A C     1 
ATOM   3350 O O     . ILE   C 2 433 ? 220.081 241.556 240.161 1.00 46.45  ? 445 ILE   A O     1 
ATOM   3351 C CB    . ILE   C 2 433 ? 221.484 238.558 240.181 1.00 41.65  ? 445 ILE   A CB    1 
ATOM   3352 C CG1   . ILE   C 2 433 ? 221.086 237.090 240.015 1.00 41.83  ? 445 ILE   A CG1   1 
ATOM   3353 C CG2   . ILE   C 2 433 ? 221.262 239.014 241.615 1.00 41.51  ? 445 ILE   A CG2   1 
ATOM   3354 C CD1   . ILE   C 2 433 ? 221.373 236.230 241.222 1.00 46.45  ? 445 ILE   A CD1   1 
ATOM   3355 N N     . ARG   C 2 434 ? 221.963 241.501 238.932 1.00 44.67  ? 446 ARG   A N     1 
ATOM   3356 C CA    . ARG   C 2 434 ? 222.169 242.940 239.058 1.00 43.99  ? 446 ARG   A CA    1 
ATOM   3357 C C     . ARG   C 2 434 ? 221.046 243.719 238.384 1.00 46.13  ? 446 ARG   A C     1 
ATOM   3358 O O     . ARG   C 2 434 ? 220.545 244.708 238.934 1.00 47.31  ? 446 ARG   A O     1 
ATOM   3359 C CB    . ARG   C 2 434 ? 223.524 243.323 238.464 1.00 45.74  ? 446 ARG   A CB    1 
ATOM   3360 C CG    . ARG   C 2 434 ? 223.934 244.758 238.712 1.00 50.39  ? 446 ARG   A CG    1 
ATOM   3361 C CD    . ARG   C 2 434 ? 225.217 245.098 237.974 1.00 55.30  ? 446 ARG   A CD    1 
ATOM   3362 N NE    . ARG   C 2 434 ? 225.089 244.942 236.531 1.00 56.61  ? 446 ARG   A NE    1 
ATOM   3363 C CZ    . ARG   C 2 434 ? 224.625 245.878 235.716 1.00 57.32  ? 446 ARG   A CZ    1 
ATOM   3364 N NH1   . ARG   C 2 434 ? 224.224 247.052 236.171 1.00 58.78  ? 446 ARG   A NH1   1 
ATOM   3365 N NH2   . ARG   C 2 434 ? 224.563 245.630 234.411 1.00 57.70  ? 446 ARG   A NH2   1 
ATOM   3366 N N     . LEU   C 2 435 ? 220.634 243.283 237.192 1.00 48.56  ? 447 LEU   A N     1 
ATOM   3367 C CA    . LEU   C 2 435 ? 219.542 243.951 236.490 1.00 45.99  ? 447 LEU   A CA    1 
ATOM   3368 C C     . LEU   C 2 435 ? 218.245 243.887 237.290 1.00 42.27  ? 447 LEU   A C     1 
ATOM   3369 O O     . LEU   C 2 435 ? 217.528 244.888 237.405 1.00 41.52  ? 447 LEU   A O     1 
ATOM   3370 C CB    . LEU   C 2 435 ? 219.348 243.324 235.109 1.00 47.63  ? 447 LEU   A CB    1 
ATOM   3371 C CG    . LEU   C 2 435 ? 220.271 243.778 233.976 1.00 45.04  ? 447 LEU   A CG    1 
ATOM   3372 C CD1   . LEU   C 2 435 ? 219.662 243.430 232.633 1.00 42.09  ? 447 LEU   A CD1   1 
ATOM   3373 C CD2   . LEU   C 2 435 ? 220.545 245.266 234.065 1.00 45.11  ? 447 LEU   A CD2   1 
ATOM   3374 N N     . MET   C 2 436 ? 217.925 242.716 237.844 1.00 43.27  ? 448 MET   A N     1 
ATOM   3375 C CA    . MET   C 2 436 ? 216.692 242.576 238.614 1.00 43.97  ? 448 MET   A CA    1 
ATOM   3376 C C     . MET   C 2 436 ? 216.749 243.378 239.908 1.00 44.38  ? 448 MET   A C     1 
ATOM   3377 O O     . MET   C 2 436 ? 215.746 243.970 240.321 1.00 45.36  ? 448 MET   A O     1 
ATOM   3378 C CB    . MET   C 2 436 ? 216.407 241.103 238.909 1.00 42.12  ? 448 MET   A CB    1 
ATOM   3379 C CG    . MET   C 2 436 ? 216.353 240.222 237.676 1.00 45.88  ? 448 MET   A CG    1 
ATOM   3380 S SD    . MET   C 2 436 ? 216.457 238.471 238.072 1.00 61.44  ? 448 MET   A SD    1 
ATOM   3381 C CE    . MET   C 2 436 ? 215.348 238.391 239.470 1.00 49.49  ? 448 MET   A CE    1 
ATOM   3382 N N     . GLU   C 2 437 ? 217.909 243.407 240.565 1.00 44.86  ? 449 GLU   A N     1 
ATOM   3383 C CA    . GLU   C 2 437 ? 218.047 244.199 241.779 1.00 45.21  ? 449 GLU   A CA    1 
ATOM   3384 C C     . GLU   C 2 437 ? 217.933 245.690 241.489 1.00 47.89  ? 449 GLU   A C     1 
ATOM   3385 O O     . GLU   C 2 437 ? 217.430 246.446 242.328 1.00 53.78  ? 449 GLU   A O     1 
ATOM   3386 C CB    . GLU   C 2 437 ? 219.378 243.882 242.458 1.00 45.62  ? 449 GLU   A CB    1 
ATOM   3387 C CG    . GLU   C 2 437 ? 219.608 244.616 243.765 1.00 52.93  ? 449 GLU   A CG    1 
ATOM   3388 C CD    . GLU   C 2 437 ? 218.644 244.189 244.849 1.00 60.98  ? 449 GLU   A CD    1 
ATOM   3389 O OE1   . GLU   C 2 437 ? 218.767 243.048 245.341 1.00 52.43  ? 449 GLU   A OE1   1 
ATOM   3390 O OE2   . GLU   C 2 437 ? 217.762 244.994 245.209 1.00 70.36  ? 449 GLU   A OE2   1 
ATOM   3391 N N     . SER   C 2 438 ? 218.384 246.130 240.311 1.00 45.29  ? 450 SER   A N     1 
ATOM   3392 C CA    . SER   C 2 438 ? 218.269 247.542 239.963 1.00 44.00  ? 450 SER   A CA    1 
ATOM   3393 C C     . SER   C 2 438 ? 216.820 247.940 239.693 1.00 45.74  ? 450 SER   A C     1 
ATOM   3394 O O     . SER   C 2 438 ? 216.449 249.104 239.877 1.00 46.54  ? 450 SER   A O     1 
ATOM   3395 C CB    . SER   C 2 438 ? 219.150 247.855 238.755 1.00 42.42  ? 450 SER   A CB    1 
ATOM   3396 O OG    . SER   C 2 438 ? 218.524 247.455 237.550 1.00 52.36  ? 450 SER   A OG    1 
ATOM   3397 N N     . ALA   C 2 439 ? 215.992 246.998 239.251 1.00 43.81  ? 451 ALA   A N     1 
ATOM   3398 C CA    . ALA   C 2 439 ? 214.608 247.309 238.920 1.00 40.91  ? 451 ALA   A CA    1 
ATOM   3399 C C     . ALA   C 2 439 ? 213.757 247.451 240.178 1.00 47.15  ? 451 ALA   A C     1 
ATOM   3400 O O     . ALA   C 2 439 ? 214.026 246.835 241.212 1.00 52.19  ? 451 ALA   A O     1 
ATOM   3401 C CB    . ALA   C 2 439 ? 214.021 246.232 238.012 1.00 38.17  ? 451 ALA   A CB    1 
ATOM   3402 N N     . ARG   C 2 440 ? 212.719 248.272 240.080 1.00 46.78  ? 452 ARG   A N     1 
ATOM   3403 C CA    . ARG   C 2 440 ? 211.802 248.549 241.173 1.00 46.87  ? 452 ARG   A CA    1 
ATOM   3404 C C     . ARG   C 2 440 ? 210.368 248.412 240.690 1.00 50.49  ? 452 ARG   A C     1 
ATOM   3405 O O     . ARG   C 2 440 ? 210.091 248.552 239.493 1.00 53.31  ? 452 ARG   A O     1 
ATOM   3406 C CB    . ARG   C 2 440 ? 212.018 249.960 241.741 1.00 45.01  ? 452 ARG   A CB    1 
ATOM   3407 C CG    . ARG   C 2 440 ? 213.471 250.346 241.898 1.00 49.79  ? 452 ARG   A CG    1 
ATOM   3408 C CD    . ARG   C 2 440 ? 213.716 251.039 243.220 1.00 52.36  ? 452 ARG   A CD    1 
ATOM   3409 N NE    . ARG   C 2 440 ? 213.911 250.081 244.299 1.00 54.67  ? 452 ARG   A NE    1 
ATOM   3410 C CZ    . ARG   C 2 440 ? 214.978 249.305 244.434 1.00 52.78  ? 452 ARG   A CZ    1 
ATOM   3411 N NH1   . ARG   C 2 440 ? 215.982 249.350 243.574 1.00 46.41  ? 452 ARG   A NH1   1 
ATOM   3412 N NH2   . ARG   C 2 440 ? 215.041 248.467 245.463 1.00 51.67  ? 452 ARG   A NH2   1 
ATOM   3413 N N     . PRO   C 2 441 ? 209.429 248.125 241.593 1.00 50.95  ? 453 PRO   A N     1 
ATOM   3414 C CA    . PRO   C 2 441 ? 208.020 248.068 241.183 1.00 48.20  ? 453 PRO   A CA    1 
ATOM   3415 C C     . PRO   C 2 441 ? 207.359 249.436 241.187 1.00 49.98  ? 453 PRO   A C     1 
ATOM   3416 O O     . PRO   C 2 441 ? 206.212 249.579 241.619 1.00 53.39  ? 453 PRO   A O     1 
ATOM   3417 C CB    . PRO   C 2 441 ? 207.394 247.142 242.229 1.00 47.24  ? 453 PRO   A CB    1 
ATOM   3418 C CG    . PRO   C 2 441 ? 208.213 247.376 243.446 1.00 50.74  ? 453 PRO   A CG    1 
ATOM   3419 C CD    . PRO   C 2 441 ? 209.616 247.674 242.982 1.00 50.93  ? 453 PRO   A CD    1 
ATOM   3420 N N     . GLU   C 2 442 ? 208.076 250.448 240.703 1.00 51.22  ? 454 GLU   A N     1 
ATOM   3421 C CA    . GLU   C 2 442 ? 207.533 251.788 240.559 1.00 49.49  ? 454 GLU   A CA    1 
ATOM   3422 C C     . GLU   C 2 442 ? 207.866 252.434 239.225 1.00 53.48  ? 454 GLU   A C     1 
ATOM   3423 O O     . GLU   C 2 442 ? 207.301 253.489 238.918 1.00 57.99  ? 454 GLU   A O     1 
ATOM   3424 C CB    . GLU   C 2 442 ? 208.032 252.703 241.688 1.00 50.11  ? 454 GLU   A CB    1 
ATOM   3425 C CG    . GLU   C 2 442 ? 207.238 252.590 242.973 1.00 52.76  ? 454 GLU   A CG    1 
ATOM   3426 C CD    . GLU   C 2 442 ? 207.956 251.778 244.028 1.00 62.08  ? 454 GLU   A CD    1 
ATOM   3427 O OE1   . GLU   C 2 442 ? 209.203 251.801 244.049 1.00 62.46  ? 454 GLU   A OE1   1 
ATOM   3428 O OE2   . GLU   C 2 442 ? 207.275 251.114 244.836 1.00 64.81  ? 454 GLU   A OE2   1 
ATOM   3429 N N     . ASP   C 2 443 ? 208.765 251.851 238.436 1.00 54.74  ? 455 ASP   A N     1 
ATOM   3430 C CA    . ASP   C 2 443 ? 209.120 252.428 237.147 1.00 54.98  ? 455 ASP   A CA    1 
ATOM   3431 C C     . ASP   C 2 443 ? 207.906 252.469 236.230 1.00 59.24  ? 455 ASP   A C     1 
ATOM   3432 O O     . ASP   C 2 443 ? 207.178 251.483 236.096 1.00 62.25  ? 455 ASP   A O     1 
ATOM   3433 C CB    . ASP   C 2 443 ? 210.246 251.623 236.500 1.00 57.35  ? 455 ASP   A CB    1 
ATOM   3434 C CG    . ASP   C 2 443 ? 211.429 251.435 237.424 1.00 64.08  ? 455 ASP   A CG    1 
ATOM   3435 O OD1   . ASP   C 2 443 ? 211.280 250.749 238.454 1.00 63.70  ? 455 ASP   A OD1   1 
ATOM   3436 O OD2   . ASP   C 2 443 ? 212.514 251.973 237.120 1.00 70.24  ? 455 ASP   A OD2   1 
ATOM   3437 N N     . VAL   C 2 444 ? 207.695 253.616 235.600 1.00 59.78  ? 456 VAL   A N     1 
ATOM   3438 C CA    . VAL   C 2 444 ? 206.549 253.806 234.723 1.00 57.50  ? 456 VAL   A CA    1 
ATOM   3439 C C     . VAL   C 2 444 ? 206.905 253.312 233.330 1.00 61.01  ? 456 VAL   A C     1 
ATOM   3440 O O     . VAL   C 2 444 ? 207.885 253.765 232.727 1.00 68.37  ? 456 VAL   A O     1 
ATOM   3441 C CB    . VAL   C 2 444 ? 206.123 255.282 234.700 1.00 51.87  ? 456 VAL   A CB    1 
ATOM   3442 C CG1   . VAL   C 2 444 ? 205.008 255.494 233.697 1.00 54.96  ? 456 VAL   A CG1   1 
ATOM   3443 C CG2   . VAL   C 2 444 ? 205.689 255.730 236.085 1.00 49.65  ? 456 VAL   A CG2   1 
ATOM   3444 N N     . SER   C 2 445 ? 206.116 252.376 232.818 1.00 57.55  ? 457 SER   A N     1 
ATOM   3445 C CA    . SER   C 2 445 ? 206.274 251.853 231.471 1.00 58.05  ? 457 SER   A CA    1 
ATOM   3446 C C     . SER   C 2 445 ? 205.116 252.319 230.601 1.00 56.81  ? 457 SER   A C     1 
ATOM   3447 O O     . SER   C 2 445 ? 204.086 252.786 231.094 1.00 58.85  ? 457 SER   A O     1 
ATOM   3448 C CB    . SER   C 2 445 ? 206.361 250.324 231.485 1.00 57.81  ? 457 SER   A CB    1 
ATOM   3449 O OG    . SER   C 2 445 ? 205.361 249.773 232.319 1.00 63.84  ? 457 SER   A OG    1 
ATOM   3450 N N     . PHE   C 2 446 ? 205.298 252.180 229.288 1.00 54.82  ? 458 PHE   A N     1 
ATOM   3451 C CA    . PHE   C 2 446 ? 204.346 252.686 228.302 1.00 54.85  ? 458 PHE   A CA    1 
ATOM   3452 C C     . PHE   C 2 446 ? 204.068 254.169 228.530 1.00 53.40  ? 458 PHE   A C     1 
ATOM   3453 O O     . PHE   C 2 446 ? 202.920 254.607 228.626 1.00 56.41  ? 458 PHE   A O     1 
ATOM   3454 C CB    . PHE   C 2 446 ? 203.048 251.879 228.319 1.00 55.33  ? 458 PHE   A CB    1 
ATOM   3455 C CG    . PHE   C 2 446 ? 203.247 250.401 228.164 1.00 51.89  ? 458 PHE   A CG    1 
ATOM   3456 C CD1   . PHE   C 2 446 ? 203.933 249.890 227.079 1.00 48.49  ? 458 PHE   A CD1   1 
ATOM   3457 C CD2   . PHE   C 2 446 ? 202.742 249.523 229.104 1.00 51.43  ? 458 PHE   A CD2   1 
ATOM   3458 C CE1   . PHE   C 2 446 ? 204.112 248.530 226.937 1.00 45.76  ? 458 PHE   A CE1   1 
ATOM   3459 C CE2   . PHE   C 2 446 ? 202.918 248.164 228.967 1.00 46.97  ? 458 PHE   A CE2   1 
ATOM   3460 C CZ    . PHE   C 2 446 ? 203.601 247.668 227.882 1.00 46.35  ? 458 PHE   A CZ    1 
ATOM   3461 N N     . GLN   C 2 447 ? 205.144 254.946 228.633 1.00 49.79  ? 459 GLN   A N     1 
ATOM   3462 C CA    . GLN   C 2 447 ? 205.013 256.374 228.885 1.00 48.14  ? 459 GLN   A CA    1 
ATOM   3463 C C     . GLN   C 2 447 ? 204.302 257.064 227.729 1.00 44.56  ? 459 GLN   A C     1 
ATOM   3464 O O     . GLN   C 2 447 ? 204.659 256.880 226.561 1.00 43.69  ? 459 GLN   A O     1 
ATOM   3465 C CB    . GLN   C 2 447 ? 206.390 256.996 229.102 1.00 49.34  ? 459 GLN   A CB    1 
ATOM   3466 C CG    . GLN   C 2 447 ? 206.817 257.055 230.552 1.00 52.08  ? 459 GLN   A CG    1 
ATOM   3467 C CD    . GLN   C 2 447 ? 206.510 258.392 231.185 1.00 56.11  ? 459 GLN   A CD    1 
ATOM   3468 O OE1   . GLN   C 2 447 ? 205.794 259.211 230.612 1.00 53.11  ? 459 GLN   A OE1   1 
ATOM   3469 N NE2   . GLN   C 2 447 ? 207.049 258.622 232.374 1.00 62.02  ? 459 GLN   A NE2   1 
ATOM   3470 N N     . GLY   C 2 448 ? 203.294 257.865 228.061 1.00 43.99  ? 460 GLY   A N     1 
ATOM   3471 C CA    . GLY   C 2 448 ? 202.556 258.618 227.074 1.00 40.76  ? 460 GLY   A CA    1 
ATOM   3472 C C     . GLY   C 2 448 ? 201.463 257.855 226.364 1.00 44.14  ? 460 GLY   A C     1 
ATOM   3473 O O     . GLY   C 2 448 ? 200.744 258.451 225.553 1.00 50.93  ? 460 GLY   A O     1 
ATOM   3474 N N     . ARG   C 2 449 ? 201.305 256.566 226.641 1.00 45.82  ? 461 ARG   A N     1 
ATOM   3475 C CA    . ARG   C 2 449 ? 200.286 255.747 226.001 1.00 47.32  ? 461 ARG   A CA    1 
ATOM   3476 C C     . ARG   C 2 449 ? 199.139 255.517 226.972 1.00 51.69  ? 461 ARG   A C     1 
ATOM   3477 O O     . ARG   C 2 449 ? 199.349 255.030 228.087 1.00 57.93  ? 461 ARG   A O     1 
ATOM   3478 C CB    . ARG   C 2 449 ? 200.874 254.415 225.535 1.00 44.37  ? 461 ARG   A CB    1 
ATOM   3479 C CG    . ARG   C 2 449 ? 202.166 254.568 224.762 1.00 46.72  ? 461 ARG   A CG    1 
ATOM   3480 C CD    . ARG   C 2 449 ? 202.353 253.445 223.763 1.00 52.91  ? 461 ARG   A CD    1 
ATOM   3481 N NE    . ARG   C 2 449 ? 203.560 253.621 222.964 1.00 60.93  ? 461 ARG   A NE    1 
ATOM   3482 C CZ    . ARG   C 2 449 ? 203.700 254.528 222.007 1.00 59.22  ? 461 ARG   A CZ    1 
ATOM   3483 N NH1   . ARG   C 2 449 ? 202.723 255.364 221.696 1.00 52.55  ? 461 ARG   A NH1   1 
ATOM   3484 N NH2   . ARG   C 2 449 ? 204.848 254.596 221.341 1.00 61.92  ? 461 ARG   A NH2   1 
ATOM   3485 N N     . GLY   C 2 450 ? 197.931 255.867 226.545 1.00 45.50  ? 462 GLY   A N     1 
ATOM   3486 C CA    . GLY   C 2 450 ? 196.778 255.777 227.415 1.00 47.15  ? 462 GLY   A CA    1 
ATOM   3487 C C     . GLY   C 2 450 ? 195.671 254.890 226.893 1.00 48.14  ? 462 GLY   A C     1 
ATOM   3488 O O     . GLY   C 2 450 ? 195.918 253.935 226.150 1.00 48.28  ? 462 GLY   A O     1 
ATOM   3489 N N     . VAL   C 2 451 ? 194.439 255.203 227.283 1.00 50.26  ? 463 VAL   A N     1 
ATOM   3490 C CA    . VAL   C 2 451 ? 193.264 254.415 226.942 1.00 46.21  ? 463 VAL   A CA    1 
ATOM   3491 C C     . VAL   C 2 451 ? 192.332 255.311 226.139 1.00 46.53  ? 463 VAL   A C     1 
ATOM   3492 O O     . VAL   C 2 451 ? 192.227 256.509 226.420 1.00 50.68  ? 463 VAL   A O     1 
ATOM   3493 C CB    . VAL   C 2 451 ? 192.558 253.879 228.199 1.00 44.41  ? 463 VAL   A CB    1 
ATOM   3494 C CG1   . VAL   C 2 451 ? 191.518 252.858 227.820 1.00 47.96  ? 463 VAL   A CG1   1 
ATOM   3495 C CG2   . VAL   C 2 451 ? 193.561 253.298 229.174 1.00 46.48  ? 463 VAL   A CG2   1 
ATOM   3496 N N     . PHE   C 2 452 ? 191.675 254.744 225.136 1.00 44.60  ? 464 PHE   A N     1 
ATOM   3497 C CA    . PHE   C 2 452 ? 190.812 255.518 224.258 1.00 45.99  ? 464 PHE   A CA    1 
ATOM   3498 C C     . PHE   C 2 452 ? 189.343 255.221 224.527 1.00 46.16  ? 464 PHE   A C     1 
ATOM   3499 O O     . PHE   C 2 452 ? 188.981 254.188 225.092 1.00 47.75  ? 464 PHE   A O     1 
ATOM   3500 C CB    . PHE   C 2 452 ? 191.138 255.231 222.793 1.00 46.11  ? 464 PHE   A CB    1 
ATOM   3501 C CG    . PHE   C 2 452 ? 192.593 255.006 222.538 1.00 48.45  ? 464 PHE   A CG    1 
ATOM   3502 C CD1   . PHE   C 2 452 ? 193.458 256.074 222.396 1.00 50.95  ? 464 PHE   A CD1   1 
ATOM   3503 C CD2   . PHE   C 2 452 ? 193.099 253.723 222.446 1.00 49.16  ? 464 PHE   A CD2   1 
ATOM   3504 C CE1   . PHE   C 2 452 ? 194.796 255.865 222.166 1.00 50.87  ? 464 PHE   A CE1   1 
ATOM   3505 C CE2   . PHE   C 2 452 ? 194.437 253.512 222.216 1.00 49.21  ? 464 PHE   A CE2   1 
ATOM   3506 C CZ    . PHE   C 2 452 ? 195.285 254.582 222.074 1.00 50.24  ? 464 PHE   A CZ    1 
ATOM   3507 N N     . GLU   C 2 453 ? 188.494 256.154 224.111 1.00 46.33  ? 465 GLU   A N     1 
ATOM   3508 C CA    . GLU   C 2 453 ? 187.055 255.978 224.184 1.00 44.93  ? 465 GLU   A CA    1 
ATOM   3509 C C     . GLU   C 2 453 ? 186.561 255.229 222.954 1.00 46.81  ? 465 GLU   A C     1 
ATOM   3510 O O     . GLU   C 2 453 ? 187.203 255.220 221.902 1.00 50.00  ? 465 GLU   A O     1 
ATOM   3511 C CB    . GLU   C 2 453 ? 186.347 257.328 224.296 1.00 43.65  ? 465 GLU   A CB    1 
ATOM   3512 C CG    . GLU   C 2 453 ? 186.380 257.929 225.685 1.00 47.37  ? 465 GLU   A CG    1 
ATOM   3513 C CD    . GLU   C 2 453 ? 185.112 258.677 226.030 1.00 56.58  ? 465 GLU   A CD    1 
ATOM   3514 O OE1   . GLU   C 2 453 ? 184.443 258.291 227.010 1.00 59.11  ? 465 GLU   A OE1   1 
ATOM   3515 O OE2   . GLU   C 2 453 ? 184.783 259.650 225.323 1.00 62.74  ? 465 GLU   A OE2   1 
ATOM   3516 N N     . LEU   C 2 454 ? 185.399 254.590 223.100 1.00 46.18  ? 466 LEU   A N     1 
ATOM   3517 C CA    . LEU   C 2 454 ? 184.832 253.827 221.996 1.00 43.86  ? 466 LEU   A CA    1 
ATOM   3518 C C     . LEU   C 2 454 ? 184.483 254.708 220.805 1.00 45.13  ? 466 LEU   A C     1 
ATOM   3519 O O     . LEU   C 2 454 ? 184.448 254.217 219.672 1.00 46.81  ? 466 LEU   A O     1 
ATOM   3520 C CB    . LEU   C 2 454 ? 183.591 253.066 222.461 1.00 43.42  ? 466 LEU   A CB    1 
ATOM   3521 C CG    . LEU   C 2 454 ? 183.772 251.589 222.813 1.00 39.11  ? 466 LEU   A CG    1 
ATOM   3522 C CD1   . LEU   C 2 454 ? 183.895 250.762 221.548 1.00 37.95  ? 466 LEU   A CD1   1 
ATOM   3523 C CD2   . LEU   C 2 454 ? 184.971 251.376 223.716 1.00 42.69  ? 466 LEU   A CD2   1 
ATOM   3524 N N     . SER   C 2 455 ? 184.223 255.996 221.032 1.00 45.09  ? 467 SER   A N     1 
ATOM   3525 C CA    . SER   C 2 455 ? 183.997 256.912 219.923 1.00 44.53  ? 467 SER   A CA    1 
ATOM   3526 C C     . SER   C 2 455 ? 185.287 257.220 219.174 1.00 47.19  ? 467 SER   A C     1 
ATOM   3527 O O     . SER   C 2 455 ? 185.251 257.488 217.969 1.00 50.64  ? 467 SER   A O     1 
ATOM   3528 C CB    . SER   C 2 455 ? 183.366 258.207 220.432 1.00 43.80  ? 467 SER   A CB    1 
ATOM   3529 O OG    . SER   C 2 455 ? 182.201 257.940 221.189 1.00 42.65  ? 467 SER   A OG    1 
ATOM   3530 N N     . ASP   C 2 456 ? 186.426 257.186 219.865 1.00 47.87  ? 468 ASP   A N     1 
ATOM   3531 C CA    . ASP   C 2 456 ? 187.725 257.492 219.268 1.00 45.72  ? 468 ASP   A CA    1 
ATOM   3532 C C     . ASP   C 2 456 ? 188.233 256.243 218.555 1.00 47.05  ? 468 ASP   A C     1 
ATOM   3533 O O     . ASP   C 2 456 ? 189.049 255.473 219.070 1.00 49.18  ? 468 ASP   A O     1 
ATOM   3534 C CB    . ASP   C 2 456 ? 188.701 257.974 220.334 1.00 47.39  ? 468 ASP   A CB    1 
ATOM   3535 C CG    . ASP   C 2 456 ? 189.918 258.658 219.748 1.00 56.71  ? 468 ASP   A CG    1 
ATOM   3536 O OD1   . ASP   C 2 456 ? 190.285 258.355 218.594 1.00 59.16  ? 468 ASP   A OD1   1 
ATOM   3537 O OD2   . ASP   C 2 456 ? 190.515 259.500 220.449 1.00 62.73  ? 468 ASP   A OD2   1 
ATOM   3538 N N     . GLU   C 2 457 ? 187.735 256.044 217.335 1.00 46.12  ? 469 GLU   A N     1 
ATOM   3539 C CA    . GLU   C 2 457 ? 188.119 254.874 216.556 1.00 48.10  ? 469 GLU   A CA    1 
ATOM   3540 C C     . GLU   C 2 457 ? 189.550 254.958 216.048 1.00 50.25  ? 469 GLU   A C     1 
ATOM   3541 O O     . GLU   C 2 457 ? 190.191 253.918 215.867 1.00 50.48  ? 469 GLU   A O     1 
ATOM   3542 C CB    . GLU   C 2 457 ? 187.160 254.693 215.381 1.00 48.90  ? 469 GLU   A CB    1 
ATOM   3543 C CG    . GLU   C 2 457 ? 185.726 254.430 215.795 1.00 52.37  ? 469 GLU   A CG    1 
ATOM   3544 C CD    . GLU   C 2 457 ? 184.924 253.747 214.708 1.00 64.21  ? 469 GLU   A CD    1 
ATOM   3545 O OE1   . GLU   C 2 457 ? 185.364 253.770 213.541 1.00 66.68  ? 469 GLU   A OE1   1 
ATOM   3546 O OE2   . GLU   C 2 457 ? 183.853 253.186 215.022 1.00 68.66  ? 469 GLU   A OE2   1 
ATOM   3547 N N     . LYS   C 2 458 ? 190.068 256.163 215.821 1.00 48.64  ? 470 LYS   A N     1 
ATOM   3548 C CA    . LYS   C 2 458 ? 191.411 256.354 215.293 1.00 47.99  ? 470 LYS   A CA    1 
ATOM   3549 C C     . LYS   C 2 458 ? 192.453 256.538 216.387 1.00 51.08  ? 470 LYS   A C     1 
ATOM   3550 O O     . LYS   C 2 458 ? 193.611 256.833 216.076 1.00 55.46  ? 470 LYS   A O     1 
ATOM   3551 C CB    . LYS   C 2 458 ? 191.438 257.550 214.342 1.00 48.70  ? 470 LYS   A CB    1 
ATOM   3552 C CG    . LYS   C 2 458 ? 190.336 257.534 213.303 1.00 49.03  ? 470 LYS   A CG    1 
ATOM   3553 C CD    . LYS   C 2 458 ? 190.488 256.355 212.364 1.00 50.37  ? 470 LYS   A CD    1 
ATOM   3554 C CE    . LYS   C 2 458 ? 190.412 256.800 210.919 1.00 54.47  ? 470 LYS   A CE    1 
ATOM   3555 N NZ    . LYS   C 2 458 ? 189.439 257.913 210.748 1.00 57.82  ? 470 LYS   A NZ    1 
ATOM   3556 N N     . ALA   C 2 459 ? 192.069 256.379 217.654 1.00 51.44  ? 471 ALA   A N     1 
ATOM   3557 C CA    . ALA   C 2 459 ? 192.991 256.493 218.785 1.00 51.47  ? 471 ALA   A CA    1 
ATOM   3558 C C     . ALA   C 2 459 ? 193.680 257.854 218.809 1.00 51.61  ? 471 ALA   A C     1 
ATOM   3559 O O     . ALA   C 2 459 ? 194.876 257.961 219.087 1.00 57.15  ? 471 ALA   A O     1 
ATOM   3560 C CB    . ALA   C 2 459 ? 194.023 255.363 218.772 1.00 49.33  ? 471 ALA   A CB    1 
ATOM   3561 N N     . THR   C 2 460 ? 192.919 258.907 218.510 1.00 50.26  ? 472 THR   A N     1 
ATOM   3562 C CA    . THR   C 2 460 ? 193.506 260.240 218.423 1.00 49.32  ? 472 THR   A CA    1 
ATOM   3563 C C     . THR   C 2 460 ? 193.862 260.791 219.800 1.00 51.33  ? 472 THR   A C     1 
ATOM   3564 O O     . THR   C 2 460 ? 194.949 261.344 219.993 1.00 53.02  ? 472 THR   A O     1 
ATOM   3565 C CB    . THR   C 2 460 ? 192.550 261.184 217.696 1.00 54.66  ? 472 THR   A CB    1 
ATOM   3566 O OG1   . THR   C 2 460 ? 191.238 261.066 218.260 1.00 64.03  ? 472 THR   A OG1   1 
ATOM   3567 C CG2   . THR   C 2 460 ? 192.489 260.840 216.219 1.00 53.57  ? 472 THR   A CG2   1 
ATOM   3568 N N     . SER   C 2 461 ? 192.962 260.651 220.770 1.00 51.73  ? 473 SER   A N     1 
ATOM   3569 C CA    . SER   C 2 461 ? 193.141 261.262 222.089 1.00 49.90  ? 473 SER   A CA    1 
ATOM   3570 C C     . SER   C 2 461 ? 193.223 260.200 223.175 1.00 51.57  ? 473 SER   A C     1 
ATOM   3571 O O     . SER   C 2 461 ? 192.186 259.664 223.602 1.00 53.27  ? 473 SER   A O     1 
ATOM   3572 C CB    . SER   C 2 461 ? 192.003 262.238 222.385 1.00 48.00  ? 473 SER   A CB    1 
ATOM   3573 O OG    . SER   C 2 461 ? 190.763 261.562 222.463 1.00 59.97  ? 473 SER   A OG    1 
ATOM   3574 N N     . PRO   C 2 462 ? 194.419 259.859 223.648 1.00 52.95  ? 474 PRO   A N     1 
ATOM   3575 C CA    . PRO   C 2 462 ? 194.533 258.890 224.742 1.00 50.34  ? 474 PRO   A CA    1 
ATOM   3576 C C     . PRO   C 2 462 ? 194.156 259.501 226.083 1.00 47.49  ? 474 PRO   A C     1 
ATOM   3577 O O     . PRO   C 2 462 ? 194.210 260.715 226.289 1.00 48.09  ? 474 PRO   A O     1 
ATOM   3578 C CB    . PRO   C 2 462 ? 196.015 258.492 224.715 1.00 49.81  ? 474 PRO   A CB    1 
ATOM   3579 C CG    . PRO   C 2 462 ? 196.547 259.010 223.410 1.00 47.97  ? 474 PRO   A CG    1 
ATOM   3580 C CD    . PRO   C 2 462 ? 195.733 260.219 223.099 1.00 51.26  ? 474 PRO   A CD    1 
ATOM   3581 N N     . ILE   C 2 463 ? 193.773 258.626 227.008 1.00 47.19  ? 475 ILE   A N     1 
ATOM   3582 C CA    . ILE   C 2 463 ? 193.470 259.000 228.385 1.00 47.78  ? 475 ILE   A CA    1 
ATOM   3583 C C     . ILE   C 2 463 ? 194.410 258.211 229.286 1.00 49.58  ? 475 ILE   A C     1 
ATOM   3584 O O     . ILE   C 2 463 ? 194.242 256.997 229.459 1.00 52.32  ? 475 ILE   A O     1 
ATOM   3585 C CB    . ILE   C 2 463 ? 192.003 258.739 228.753 1.00 46.86  ? 475 ILE   A CB    1 
ATOM   3586 C CG1   . ILE   C 2 463 ? 191.079 259.698 228.002 1.00 43.18  ? 475 ILE   A CG1   1 
ATOM   3587 C CG2   . ILE   C 2 463 ? 191.796 258.887 230.249 1.00 50.44  ? 475 ILE   A CG2   1 
ATOM   3588 C CD1   . ILE   C 2 463 ? 190.447 259.106 226.769 1.00 44.89  ? 475 ILE   A CD1   1 
ATOM   3589 N N     . VAL   C 2 464 ? 195.402 258.890 229.850 1.00 47.60  ? 476 VAL   A N     1 
ATOM   3590 C CA    . VAL   C 2 464 ? 196.349 258.254 230.760 1.00 49.17  ? 476 VAL   A CA    1 
ATOM   3591 C C     . VAL   C 2 464 ? 195.678 258.081 232.116 1.00 53.48  ? 476 VAL   A C     1 
ATOM   3592 O O     . VAL   C 2 464 ? 195.220 259.069 232.708 1.00 59.99  ? 476 VAL   A O     1 
ATOM   3593 C CB    . VAL   C 2 464 ? 197.645 259.068 230.879 1.00 52.66  ? 476 VAL   A CB    1 
ATOM   3594 C CG1   . VAL   C 2 464 ? 198.509 258.518 231.995 1.00 57.41  ? 476 VAL   A CG1   1 
ATOM   3595 C CG2   . VAL   C 2 464 ? 198.399 259.049 229.563 1.00 52.75  ? 476 VAL   A CG2   1 
ATOM   3596 N N     . PRO   C 2 465 ? 195.589 256.864 232.641 1.00 51.14  ? 477 PRO   A N     1 
ATOM   3597 C CA    . PRO   C 2 465 ? 194.911 256.663 233.922 1.00 52.25  ? 477 PRO   A CA    1 
ATOM   3598 C C     . PRO   C 2 465 ? 195.729 257.201 235.085 1.00 49.58  ? 477 PRO   A C     1 
ATOM   3599 O O     . PRO   C 2 465 ? 196.953 257.332 235.023 1.00 48.69  ? 477 PRO   A O     1 
ATOM   3600 C CB    . PRO   C 2 465 ? 194.763 255.143 234.007 1.00 52.59  ? 477 PRO   A CB    1 
ATOM   3601 C CG    . PRO   C 2 465 ? 195.904 254.625 233.210 1.00 50.99  ? 477 PRO   A CG    1 
ATOM   3602 C CD    . PRO   C 2 465 ? 196.100 255.601 232.084 1.00 49.23  ? 477 PRO   A CD    1 
ATOM   3603 N N     . SER   C 2 466 ? 195.021 257.518 236.164 1.00 50.43  ? 478 SER   A N     1 
ATOM   3604 C CA    . SER   C 2 466 ? 195.625 257.980 237.406 1.00 55.68  ? 478 SER   A CA    1 
ATOM   3605 C C     . SER   C 2 466 ? 195.354 256.945 238.486 1.00 57.08  ? 478 SER   A C     1 
ATOM   3606 O O     . SER   C 2 466 ? 194.194 256.616 238.756 1.00 61.85  ? 478 SER   A O     1 
ATOM   3607 C CB    . SER   C 2 466 ? 195.066 259.341 237.814 1.00 62.04  ? 478 SER   A CB    1 
ATOM   3608 O OG    . SER   C 2 466 ? 193.670 259.266 238.041 1.00 64.66  ? 478 SER   A OG    1 
ATOM   3609 N N     . PHE   C 2 467 ? 196.415 256.440 239.102 1.00 54.44  ? 479 PHE   A N     1 
ATOM   3610 C CA    . PHE   C 2 467 ? 196.278 255.417 240.129 1.00 57.54  ? 479 PHE   A CA    1 
ATOM   3611 C C     . PHE   C 2 467 ? 196.900 255.868 241.445 1.00 53.30  ? 479 PHE   A C     1 
ATOM   3612 O O     . PHE   C 2 467 ? 197.343 255.047 242.247 1.00 50.20  ? 479 PHE   A O     1 
ATOM   3613 C CB    . PHE   C 2 467 ? 196.915 254.107 239.666 1.00 57.69  ? 479 PHE   A CB    1 
ATOM   3614 C CG    . PHE   C 2 467 ? 196.259 253.505 238.453 1.00 54.23  ? 479 PHE   A CG    1 
ATOM   3615 C CD1   . PHE   C 2 467 ? 194.882 253.474 238.339 1.00 50.54  ? 479 PHE   A CD1   1 
ATOM   3616 C CD2   . PHE   C 2 467 ? 197.023 252.969 237.431 1.00 51.05  ? 479 PHE   A CD2   1 
ATOM   3617 C CE1   . PHE   C 2 467 ? 194.280 252.921 237.227 1.00 50.33  ? 479 PHE   A CE1   1 
ATOM   3618 C CE2   . PHE   C 2 467 ? 196.424 252.412 236.320 1.00 45.64  ? 479 PHE   A CE2   1 
ATOM   3619 C CZ    . PHE   C 2 467 ? 195.052 252.389 236.218 1.00 47.55  ? 479 PHE   A CZ    1 
ATOM   3620 N N     . GLU   C 2 472 ? 194.692 249.432 246.463 1.00 60.79  ? 484 GLU   A N     1 
ATOM   3621 C CA    . GLU   C 2 472 ? 193.803 248.482 245.805 1.00 67.84  ? 484 GLU   A CA    1 
ATOM   3622 C C     . GLU   C 2 472 ? 194.590 247.280 245.297 1.00 63.60  ? 484 GLU   A C     1 
ATOM   3623 O O     . GLU   C 2 472 ? 195.792 247.374 245.053 1.00 64.00  ? 484 GLU   A O     1 
ATOM   3624 C CB    . GLU   C 2 472 ? 193.032 249.136 244.645 1.00 71.41  ? 484 GLU   A CB    1 
ATOM   3625 C CG    . GLU   C 2 472 ? 192.275 250.439 244.962 1.00 82.14  ? 484 GLU   A CG    1 
ATOM   3626 C CD    . GLU   C 2 472 ? 193.165 251.589 245.401 1.00 80.61  ? 484 GLU   A CD    1 
ATOM   3627 O OE1   . GLU   C 2 472 ? 192.999 252.070 246.542 1.00 66.71  ? 484 GLU   A OE1   1 
ATOM   3628 O OE2   . GLU   C 2 472 ? 194.027 252.014 244.604 1.00 83.75  ? 484 GLU   A OE2   1 
ATOM   3629 N N     . GLY   C 2 473 ? 193.904 246.149 245.145 1.00 55.72  ? 485 GLY   A N     1 
ATOM   3630 C CA    . GLY   C 2 473 ? 194.562 244.945 244.690 1.00 52.10  ? 485 GLY   A CA    1 
ATOM   3631 C C     . GLY   C 2 473 ? 195.034 245.051 243.254 1.00 52.97  ? 485 GLY   A C     1 
ATOM   3632 O O     . GLY   C 2 473 ? 194.501 245.806 242.442 1.00 57.16  ? 485 GLY   A O     1 
ATOM   3633 N N     . SER   C 2 474 ? 196.063 244.269 242.937 1.00 46.87  ? 486 SER   A N     1 
ATOM   3634 C CA    . SER   C 2 474 ? 196.659 244.328 241.610 1.00 45.61  ? 486 SER   A CA    1 
ATOM   3635 C C     . SER   C 2 474 ? 196.941 242.968 240.987 1.00 47.00  ? 486 SER   A C     1 
ATOM   3636 O O     . SER   C 2 474 ? 197.351 242.925 239.825 1.00 47.58  ? 486 SER   A O     1 
ATOM   3637 C CB    . SER   C 2 474 ? 197.962 245.137 241.654 1.00 46.22  ? 486 SER   A CB    1 
ATOM   3638 O OG    . SER   C 2 474 ? 198.759 244.872 240.515 1.00 53.63  ? 486 SER   A OG    1 
ATOM   3639 N N     . TYR   C 2 475 ? 196.727 241.866 241.700 1.00 46.45  ? 487 TYR   A N     1 
ATOM   3640 C CA    . TYR   C 2 475 ? 196.977 240.531 241.171 1.00 44.36  ? 487 TYR   A CA    1 
ATOM   3641 C C     . TYR   C 2 475 ? 195.677 239.747 241.136 1.00 44.83  ? 487 TYR   A C     1 
ATOM   3642 O O     . TYR   C 2 475 ? 194.942 239.709 242.127 1.00 45.22  ? 487 TYR   A O     1 
ATOM   3643 C CB    . TYR   C 2 475 ? 198.023 239.784 242.007 1.00 44.81  ? 487 TYR   A CB    1 
ATOM   3644 C CG    . TYR   C 2 475 ? 199.289 240.567 242.260 1.00 51.53  ? 487 TYR   A CG    1 
ATOM   3645 C CD1   . TYR   C 2 475 ? 200.300 240.604 241.314 1.00 52.05  ? 487 TYR   A CD1   1 
ATOM   3646 C CD2   . TYR   C 2 475 ? 199.472 241.271 243.440 1.00 57.35  ? 487 TYR   A CD2   1 
ATOM   3647 C CE1   . TYR   C 2 475 ? 201.460 241.315 241.534 1.00 54.24  ? 487 TYR   A CE1   1 
ATOM   3648 C CE2   . TYR   C 2 475 ? 200.631 241.988 243.669 1.00 58.86  ? 487 TYR   A CE2   1 
ATOM   3649 C CZ    . TYR   C 2 475 ? 201.620 242.006 242.711 1.00 59.14  ? 487 TYR   A CZ    1 
ATOM   3650 O OH    . TYR   C 2 475 ? 202.774 242.717 242.934 1.00 65.34  ? 487 TYR   A OH    1 
ATOM   3651 N N     . PHE   C 2 476 ? 195.392 239.133 239.987 1.00 44.14  ? 488 PHE   A N     1 
ATOM   3652 C CA    . PHE   C 2 476 ? 194.186 238.325 239.857 1.00 44.03  ? 488 PHE   A CA    1 
ATOM   3653 C C     . PHE   C 2 476 ? 194.310 237.027 240.641 1.00 44.94  ? 488 PHE   A C     1 
ATOM   3654 O O     . PHE   C 2 476 ? 193.438 236.689 241.448 1.00 46.27  ? 488 PHE   A O     1 
ATOM   3655 C CB    . PHE   C 2 476 ? 193.908 238.039 238.382 1.00 42.45  ? 488 PHE   A CB    1 
ATOM   3656 C CG    . PHE   C 2 476 ? 192.577 237.393 238.125 1.00 43.36  ? 488 PHE   A CG    1 
ATOM   3657 C CD1   . PHE   C 2 476 ? 191.400 238.029 238.472 1.00 43.39  ? 488 PHE   A CD1   1 
ATOM   3658 C CD2   . PHE   C 2 476 ? 192.505 236.143 237.537 1.00 43.61  ? 488 PHE   A CD2   1 
ATOM   3659 C CE1   . PHE   C 2 476 ? 190.179 237.433 238.233 1.00 42.35  ? 488 PHE   A CE1   1 
ATOM   3660 C CE2   . PHE   C 2 476 ? 191.288 235.541 237.298 1.00 41.35  ? 488 PHE   A CE2   1 
ATOM   3661 C CZ    . PHE   C 2 476 ? 190.124 236.187 237.649 1.00 39.59  ? 488 PHE   A CZ    1 
ATOM   3662 N N     . PHE   C 2 477 ? 195.396 236.296 240.428 1.00 41.84  ? 489 PHE   A N     1 
ATOM   3663 C CA    . PHE   C 2 477 ? 195.591 234.987 241.048 1.00 44.23  ? 489 PHE   A CA    1 
ATOM   3664 C C     . PHE   C 2 477 ? 196.411 235.098 242.328 1.00 45.22  ? 489 PHE   A C     1 
ATOM   3665 O O     . PHE   C 2 477 ? 197.417 234.413 242.502 1.00 45.99  ? 489 PHE   A O     1 
ATOM   3666 C CB    . PHE   C 2 477 ? 196.254 234.039 240.060 1.00 47.37  ? 489 PHE   A CB    1 
ATOM   3667 C CG    . PHE   C 2 477 ? 195.353 233.602 238.941 1.00 46.57  ? 489 PHE   A CG    1 
ATOM   3668 C CD1   . PHE   C 2 477 ? 194.081 233.124 239.198 1.00 43.59  ? 489 PHE   A CD1   1 
ATOM   3669 C CD2   . PHE   C 2 477 ? 195.789 233.650 237.631 1.00 48.54  ? 489 PHE   A CD2   1 
ATOM   3670 C CE1   . PHE   C 2 477 ? 193.260 232.717 238.168 1.00 41.88  ? 489 PHE   A CE1   1 
ATOM   3671 C CE2   . PHE   C 2 477 ? 194.974 233.244 236.600 1.00 47.79  ? 489 PHE   A CE2   1 
ATOM   3672 C CZ    . PHE   C 2 477 ? 193.708 232.777 236.869 1.00 45.04  ? 489 PHE   A CZ    1 
ATOM   3673 N N     . GLY   C 2 478 ? 195.990 235.963 243.244 1.00 39.98  ? 490 GLY   A N     1 
ATOM   3674 C CA    . GLY   C 2 478 ? 196.720 236.172 244.480 1.00 39.68  ? 490 GLY   A CA    1 
ATOM   3675 C C     . GLY   C 2 478 ? 195.927 235.824 245.724 1.00 34.23  ? 490 GLY   A C     1 
ATOM   3676 O O     . GLY   C 2 478 ? 196.484 235.714 246.816 1.00 22.32  ? 490 GLY   A O     1 
ATOM   3677 N N     . SER   D 2 390 ? 201.559 231.342 251.808 1.00 70.78  ? 402 SER   B N     1 
ATOM   3678 C CA    . SER   D 2 390 ? 200.685 230.848 250.751 1.00 74.82  ? 402 SER   B CA    1 
ATOM   3679 C C     . SER   D 2 390 ? 201.110 231.397 249.393 1.00 75.99  ? 402 SER   B C     1 
ATOM   3680 O O     . SER   D 2 390 ? 201.462 232.569 249.268 1.00 76.52  ? 402 SER   B O     1 
ATOM   3681 C CB    . SER   D 2 390 ? 199.231 231.218 251.043 1.00 74.57  ? 402 SER   B CB    1 
ATOM   3682 O OG    . SER   D 2 390 ? 198.718 230.439 252.108 1.00 74.60  ? 402 SER   B OG    1 
ATOM   3683 N N     . SER   D 2 391 ? 201.075 230.540 248.379 1.00 75.50  ? 403 SER   B N     1 
ATOM   3684 C CA    . SER   D 2 391 ? 201.498 230.919 247.044 1.00 74.16  ? 403 SER   B CA    1 
ATOM   3685 C C     . SER   D 2 391 ? 200.425 231.755 246.350 1.00 71.21  ? 403 SER   B C     1 
ATOM   3686 O O     . SER   D 2 391 ? 199.280 231.850 246.797 1.00 73.71  ? 403 SER   B O     1 
ATOM   3687 C CB    . SER   D 2 391 ? 201.825 229.679 246.216 1.00 79.02  ? 403 SER   B CB    1 
ATOM   3688 O OG    . SER   D 2 391 ? 202.566 228.743 246.977 1.00 81.59  ? 403 SER   B OG    1 
ATOM   3689 N N     . GLY   D 2 392 ? 200.816 232.368 245.241 1.00 66.08  ? 404 GLY   B N     1 
ATOM   3690 C CA    . GLY   D 2 392 ? 199.891 233.159 244.457 1.00 61.44  ? 404 GLY   B CA    1 
ATOM   3691 C C     . GLY   D 2 392 ? 200.632 233.888 243.356 1.00 60.76  ? 404 GLY   B C     1 
ATOM   3692 O O     . GLY   D 2 392 ? 201.840 233.720 243.181 1.00 62.09  ? 404 GLY   B O     1 
ATOM   3693 N N     . GLN   D 2 393 ? 199.882 234.698 242.614 1.00 59.27  ? 405 GLN   B N     1 
ATOM   3694 C CA    . GLN   D 2 393 ? 200.493 235.517 241.579 1.00 57.73  ? 405 GLN   B CA    1 
ATOM   3695 C C     . GLN   D 2 393 ? 201.406 236.556 242.212 1.00 57.23  ? 405 GLN   B C     1 
ATOM   3696 O O     . GLN   D 2 393 ? 201.083 237.146 243.246 1.00 55.18  ? 405 GLN   B O     1 
ATOM   3697 C CB    . GLN   D 2 393 ? 199.426 236.197 240.725 1.00 57.96  ? 405 GLN   B CB    1 
ATOM   3698 C CG    . GLN   D 2 393 ? 199.967 236.790 239.438 1.00 54.25  ? 405 GLN   B CG    1 
ATOM   3699 C CD    . GLN   D 2 393 ? 198.933 237.593 238.686 1.00 58.78  ? 405 GLN   B CD    1 
ATOM   3700 O OE1   . GLN   D 2 393 ? 197.830 237.821 239.178 1.00 62.62  ? 405 GLN   B OE1   1 
ATOM   3701 N NE2   . GLN   D 2 393 ? 199.285 238.031 237.486 1.00 58.39  ? 405 GLN   B NE2   1 
ATOM   3702 N N     . ILE   D 2 394 ? 202.566 236.769 241.591 1.00 55.75  ? 406 ILE   B N     1 
ATOM   3703 C CA    . ILE   D 2 394 ? 203.595 237.638 242.135 1.00 53.97  ? 406 ILE   B CA    1 
ATOM   3704 C C     . ILE   D 2 394 ? 203.960 238.762 241.173 1.00 53.71  ? 406 ILE   B C     1 
ATOM   3705 O O     . ILE   D 2 394 ? 204.437 239.818 241.602 1.00 55.77  ? 406 ILE   B O     1 
ATOM   3706 C CB    . ILE   D 2 394 ? 204.846 236.820 242.530 1.00 53.10  ? 406 ILE   B CB    1 
ATOM   3707 C CG1   . ILE   D 2 394 ? 205.466 237.366 243.812 1.00 53.96  ? 406 ILE   B CG1   1 
ATOM   3708 C CG2   . ILE   D 2 394 ? 205.873 236.807 241.411 1.00 54.06  ? 406 ILE   B CG2   1 
ATOM   3709 C CD1   . ILE   D 2 394 ? 206.721 236.638 244.214 1.00 52.85  ? 406 ILE   B CD1   1 
ATOM   3710 N N     . SER   D 2 395 ? 203.746 238.563 239.876 1.00 51.51  ? 407 SER   B N     1 
ATOM   3711 C CA    . SER   D 2 395 ? 204.065 239.551 238.858 1.00 51.93  ? 407 SER   B CA    1 
ATOM   3712 C C     . SER   D 2 395 ? 202.816 239.922 238.065 1.00 52.81  ? 407 SER   B C     1 
ATOM   3713 O O     . SER   D 2 395 ? 201.715 239.429 238.319 1.00 56.93  ? 407 SER   B O     1 
ATOM   3714 C CB    . SER   D 2 395 ? 205.163 239.022 237.935 1.00 55.64  ? 407 SER   B CB    1 
ATOM   3715 O OG    . SER   D 2 395 ? 205.255 239.793 236.753 1.00 61.18  ? 407 SER   B OG    1 
ATOM   3716 N N     . ILE   D 2 396 ? 203.013 240.786 237.071 1.00 51.17  ? 408 ILE   B N     1 
ATOM   3717 C CA    . ILE   D 2 396 ? 201.956 241.259 236.181 1.00 49.40  ? 408 ILE   B CA    1 
ATOM   3718 C C     . ILE   D 2 396 ? 202.459 241.167 234.749 1.00 51.57  ? 408 ILE   B C     1 
ATOM   3719 O O     . ILE   D 2 396 ? 203.595 241.554 234.462 1.00 58.31  ? 408 ILE   B O     1 
ATOM   3720 C CB    . ILE   D 2 396 ? 201.533 242.707 236.505 1.00 50.46  ? 408 ILE   B CB    1 
ATOM   3721 C CG1   . ILE   D 2 396 ? 200.953 242.798 237.911 1.00 53.64  ? 408 ILE   B CG1   1 
ATOM   3722 C CG2   . ILE   D 2 396 ? 200.523 243.214 235.496 1.00 46.30  ? 408 ILE   B CG2   1 
ATOM   3723 C CD1   . ILE   D 2 396 ? 199.803 241.859 238.125 1.00 56.72  ? 408 ILE   B CD1   1 
ATOM   3724 N N     . GLN   D 2 397 ? 201.623 240.653 233.856 1.00 48.61  ? 409 GLN   B N     1 
ATOM   3725 C CA    . GLN   D 2 397 ? 201.972 240.604 232.442 1.00 50.34  ? 409 GLN   B CA    1 
ATOM   3726 C C     . GLN   D 2 397 ? 201.155 241.648 231.688 1.00 54.18  ? 409 GLN   B C     1 
ATOM   3727 O O     . GLN   D 2 397 ? 199.927 241.535 231.633 1.00 59.18  ? 409 GLN   B O     1 
ATOM   3728 C CB    . GLN   D 2 397 ? 201.717 239.216 231.879 1.00 52.31  ? 409 GLN   B CB    1 
ATOM   3729 C CG    . GLN   D 2 397 ? 202.098 239.057 230.421 1.00 55.26  ? 409 GLN   B CG    1 
ATOM   3730 C CD    . GLN   D 2 397 ? 203.588 239.223 230.192 1.00 49.57  ? 409 GLN   B CD    1 
ATOM   3731 O OE1   . GLN   D 2 397 ? 204.403 238.728 230.968 1.00 42.79  ? 409 GLN   B OE1   1 
ATOM   3732 N NE2   . GLN   D 2 397 ? 203.951 239.918 229.122 1.00 49.21  ? 409 GLN   B NE2   1 
ATOM   3733 N N     . PRO   D 2 398 ? 201.784 242.658 231.094 1.00 52.98  ? 410 PRO   B N     1 
ATOM   3734 C CA    . PRO   D 2 398 ? 201.033 243.804 230.560 1.00 56.47  ? 410 PRO   B CA    1 
ATOM   3735 C C     . PRO   D 2 398 ? 200.351 243.557 229.222 1.00 61.09  ? 410 PRO   B C     1 
ATOM   3736 O O     . PRO   D 2 398 ? 200.932 243.862 228.178 1.00 66.35  ? 410 PRO   B O     1 
ATOM   3737 C CB    . PRO   D 2 398 ? 202.112 244.884 230.429 1.00 59.91  ? 410 PRO   B CB    1 
ATOM   3738 C CG    . PRO   D 2 398 ? 203.371 244.125 230.219 1.00 58.67  ? 410 PRO   B CG    1 
ATOM   3739 C CD    . PRO   D 2 398 ? 203.241 242.850 230.997 1.00 56.11  ? 410 PRO   B CD    1 
ATOM   3740 N N     . THR   D 2 399 ? 199.138 242.996 229.224 1.00 59.73  ? 411 THR   B N     1 
ATOM   3741 C CA    . THR   D 2 399 ? 198.448 242.747 227.959 1.00 63.31  ? 411 THR   B CA    1 
ATOM   3742 C C     . THR   D 2 399 ? 198.065 244.051 227.261 1.00 64.49  ? 411 THR   B C     1 
ATOM   3743 O O     . THR   D 2 399 ? 198.148 244.152 226.033 1.00 67.40  ? 411 THR   B O     1 
ATOM   3744 C CB    . THR   D 2 399 ? 197.210 241.872 228.174 1.00 61.26  ? 411 THR   B CB    1 
ATOM   3745 O OG1   . THR   D 2 399 ? 196.429 241.852 226.973 1.00 66.25  ? 411 THR   B OG1   1 
ATOM   3746 C CG2   . THR   D 2 399 ? 196.352 242.406 229.281 1.00 58.60  ? 411 THR   B CG2   1 
ATOM   3747 N N     . PHE   D 2 400 ? 197.636 245.055 228.020 1.00 58.36  ? 412 PHE   B N     1 
ATOM   3748 C CA    . PHE   D 2 400 ? 197.208 246.328 227.455 1.00 56.04  ? 412 PHE   B CA    1 
ATOM   3749 C C     . PHE   D 2 400 ? 198.375 247.306 227.396 1.00 57.86  ? 412 PHE   B C     1 
ATOM   3750 O O     . PHE   D 2 400 ? 199.218 247.338 228.296 1.00 62.10  ? 412 PHE   B O     1 
ATOM   3751 C CB    . PHE   D 2 400 ? 196.065 246.937 228.269 1.00 56.60  ? 412 PHE   B CB    1 
ATOM   3752 C CG    . PHE   D 2 400 ? 194.782 246.163 228.188 1.00 59.58  ? 412 PHE   B CG    1 
ATOM   3753 C CD1   . PHE   D 2 400 ? 193.976 246.250 227.068 1.00 58.06  ? 412 PHE   B CD1   1 
ATOM   3754 C CD2   . PHE   D 2 400 ? 194.373 245.361 229.237 1.00 60.99  ? 412 PHE   B CD2   1 
ATOM   3755 C CE1   . PHE   D 2 400 ? 192.797 245.542 226.990 1.00 56.37  ? 412 PHE   B CE1   1 
ATOM   3756 C CE2   . PHE   D 2 400 ? 193.195 244.652 229.166 1.00 60.75  ? 412 PHE   B CE2   1 
ATOM   3757 C CZ    . PHE   D 2 400 ? 192.406 244.743 228.041 1.00 58.46  ? 412 PHE   B CZ    1 
ATOM   3758 N N     . SER   D 2 401 ? 198.415 248.102 226.327 1.00 56.97  ? 413 SER   B N     1 
ATOM   3759 C CA    . SER   D 2 401 ? 199.450 249.121 226.140 1.00 56.49  ? 413 SER   B CA    1 
ATOM   3760 C C     . SER   D 2 401 ? 198.974 250.422 226.779 1.00 56.57  ? 413 SER   B C     1 
ATOM   3761 O O     . SER   D 2 401 ? 198.483 251.341 226.119 1.00 58.61  ? 413 SER   B O     1 
ATOM   3762 C CB    . SER   D 2 401 ? 199.761 249.303 224.661 1.00 56.81  ? 413 SER   B CB    1 
ATOM   3763 O OG    . SER   D 2 401 ? 200.715 250.331 224.464 1.00 60.98  ? 413 SER   B OG    1 
ATOM   3764 N N     . VAL   D 2 402 ? 199.126 250.496 228.098 1.00 53.44  ? 414 VAL   B N     1 
ATOM   3765 C CA    . VAL   D 2 402 ? 198.612 251.601 228.895 1.00 50.65  ? 414 VAL   B CA    1 
ATOM   3766 C C     . VAL   D 2 402 ? 199.696 252.030 229.875 1.00 52.97  ? 414 VAL   B C     1 
ATOM   3767 O O     . VAL   D 2 402 ? 200.414 251.185 230.421 1.00 57.99  ? 414 VAL   B O     1 
ATOM   3768 C CB    . VAL   D 2 402 ? 197.321 251.194 229.640 1.00 51.13  ? 414 VAL   B CB    1 
ATOM   3769 C CG1   . VAL   D 2 402 ? 196.946 252.220 230.694 1.00 48.35  ? 414 VAL   B CG1   1 
ATOM   3770 C CG2   . VAL   D 2 402 ? 196.186 250.979 228.656 1.00 53.35  ? 414 VAL   B CG2   1 
ATOM   3771 N N     . GLN   D 2 403 ? 199.825 253.340 230.085 1.00 51.35  ? 415 GLN   B N     1 
ATOM   3772 C CA    . GLN   D 2 403 ? 200.821 253.854 231.018 1.00 51.06  ? 415 GLN   B CA    1 
ATOM   3773 C C     . GLN   D 2 403 ? 200.589 253.275 232.409 1.00 53.56  ? 415 GLN   B C     1 
ATOM   3774 O O     . GLN   D 2 403 ? 199.570 253.551 233.047 1.00 51.52  ? 415 GLN   B O     1 
ATOM   3775 C CB    . GLN   D 2 403 ? 200.777 255.380 231.059 1.00 46.28  ? 415 GLN   B CB    1 
ATOM   3776 C CG    . GLN   D 2 403 ? 202.015 256.004 231.682 1.00 46.74  ? 415 GLN   B CG    1 
ATOM   3777 C CD    . GLN   D 2 403 ? 201.937 257.513 231.781 1.00 47.53  ? 415 GLN   B CD    1 
ATOM   3778 O OE1   . GLN   D 2 403 ? 202.129 258.223 230.796 1.00 48.76  ? 415 GLN   B OE1   1 
ATOM   3779 N NE2   . GLN   D 2 403 ? 201.666 258.013 232.979 1.00 47.23  ? 415 GLN   B NE2   1 
ATOM   3780 N N     . ARG   D 2 404 ? 201.546 252.478 232.875 1.00 54.72  ? 416 ARG   B N     1 
ATOM   3781 C CA    . ARG   D 2 404 ? 201.396 251.693 234.090 1.00 49.86  ? 416 ARG   B CA    1 
ATOM   3782 C C     . ARG   D 2 404 ? 202.726 251.674 234.832 1.00 53.12  ? 416 ARG   B C     1 
ATOM   3783 O O     . ARG   D 2 404 ? 203.718 252.255 234.384 1.00 54.93  ? 416 ARG   B O     1 
ATOM   3784 C CB    . ARG   D 2 404 ? 200.938 250.271 233.758 1.00 50.46  ? 416 ARG   B CB    1 
ATOM   3785 C CG    . ARG   D 2 404 ? 199.593 249.878 234.327 1.00 55.71  ? 416 ARG   B CG    1 
ATOM   3786 C CD    . ARG   D 2 404 ? 199.366 248.393 234.117 1.00 56.80  ? 416 ARG   B CD    1 
ATOM   3787 N NE    . ARG   D 2 404 ? 200.019 247.935 232.899 1.00 52.35  ? 416 ARG   B NE    1 
ATOM   3788 C CZ    . ARG   D 2 404 ? 199.415 247.807 231.726 1.00 54.12  ? 416 ARG   B CZ    1 
ATOM   3789 N NH1   . ARG   D 2 404 ? 198.125 248.057 231.583 1.00 57.81  ? 416 ARG   B NH1   1 
ATOM   3790 N NH2   . ARG   D 2 404 ? 200.122 247.419 230.671 1.00 57.60  ? 416 ARG   B NH2   1 
ATOM   3791 N N     . ASN   D 2 405 ? 202.745 250.996 235.979 1.00 52.73  ? 417 ASN   B N     1 
ATOM   3792 C CA    . ASN   D 2 405 ? 203.970 250.799 236.736 1.00 53.31  ? 417 ASN   B CA    1 
ATOM   3793 C C     . ASN   D 2 405 ? 204.390 249.339 236.869 1.00 53.69  ? 417 ASN   B C     1 
ATOM   3794 O O     . ASN   D 2 405 ? 205.478 249.076 237.390 1.00 55.18  ? 417 ASN   B O     1 
ATOM   3795 C CB    . ASN   D 2 405 ? 203.852 251.458 238.125 1.00 51.21  ? 417 ASN   B CB    1 
ATOM   3796 C CG    . ASN   D 2 405 ? 202.989 250.669 239.104 1.00 55.03  ? 417 ASN   B CG    1 
ATOM   3797 O OD1   . ASN   D 2 405 ? 202.474 249.596 238.799 1.00 60.84  ? 417 ASN   B OD1   1 
ATOM   3798 N ND2   . ASN   D 2 405 ? 202.831 251.216 240.302 1.00 52.76  ? 417 ASN   B ND2   1 
ATOM   3799 N N     . LEU   D 2 406 ? 203.569 248.393 236.400 1.00 53.06  ? 418 LEU   B N     1 
ATOM   3800 C CA    . LEU   D 2 406 ? 203.899 246.970 236.358 1.00 52.80  ? 418 LEU   B CA    1 
ATOM   3801 C C     . LEU   D 2 406 ? 204.346 246.441 237.716 1.00 52.54  ? 418 LEU   B C     1 
ATOM   3802 O O     . LEU   D 2 406 ? 205.539 246.190 237.921 1.00 50.90  ? 418 LEU   B O     1 
ATOM   3803 C CB    . LEU   D 2 406 ? 204.979 246.709 235.308 1.00 50.91  ? 418 LEU   B CB    1 
ATOM   3804 C CG    . LEU   D 2 406 ? 204.579 247.034 233.870 1.00 49.58  ? 418 LEU   B CG    1 
ATOM   3805 C CD1   . LEU   D 2 406 ? 205.615 246.511 232.900 1.00 51.38  ? 418 LEU   B CD1   1 
ATOM   3806 C CD2   . LEU   D 2 406 ? 203.213 246.454 233.555 1.00 50.02  ? 418 LEU   B CD2   1 
ATOM   3807 N N     . PRO   D 2 407 ? 203.427 246.275 238.664 1.00 54.55  ? 419 PRO   B N     1 
ATOM   3808 C CA    . PRO   D 2 407 ? 203.829 245.874 240.017 1.00 52.44  ? 419 PRO   B CA    1 
ATOM   3809 C C     . PRO   D 2 407 ? 204.421 244.473 240.048 1.00 49.99  ? 419 PRO   B C     1 
ATOM   3810 O O     . PRO   D 2 407 ? 204.083 243.612 239.234 1.00 51.60  ? 419 PRO   B O     1 
ATOM   3811 C CB    . PRO   D 2 407 ? 202.516 245.934 240.807 1.00 54.00  ? 419 PRO   B CB    1 
ATOM   3812 C CG    . PRO   D 2 407 ? 201.584 246.735 239.968 1.00 54.16  ? 419 PRO   B CG    1 
ATOM   3813 C CD    . PRO   D 2 407 ? 201.973 246.449 238.557 1.00 55.43  ? 419 PRO   B CD    1 
ATOM   3814 N N     . PHE   D 2 408 ? 205.323 244.259 241.002 1.00 47.73  ? 420 PHE   B N     1 
ATOM   3815 C CA    . PHE   D 2 408 ? 205.780 242.921 241.350 1.00 49.25  ? 420 PHE   B CA    1 
ATOM   3816 C C     . PHE   D 2 408 ? 206.260 242.953 242.792 1.00 51.09  ? 420 PHE   B C     1 
ATOM   3817 O O     . PHE   D 2 408 ? 206.671 243.997 243.304 1.00 54.34  ? 420 PHE   B O     1 
ATOM   3818 C CB    . PHE   D 2 408 ? 206.874 242.420 240.398 1.00 49.20  ? 420 PHE   B CB    1 
ATOM   3819 C CG    . PHE   D 2 408 ? 208.134 243.238 240.418 1.00 46.08  ? 420 PHE   B CG    1 
ATOM   3820 C CD1   . PHE   D 2 408 ? 208.272 244.338 239.592 1.00 49.22  ? 420 PHE   B CD1   1 
ATOM   3821 C CD2   . PHE   D 2 408 ? 209.185 242.898 241.250 1.00 45.49  ? 420 PHE   B CD2   1 
ATOM   3822 C CE1   . PHE   D 2 408 ? 209.429 245.088 239.603 1.00 49.90  ? 420 PHE   B CE1   1 
ATOM   3823 C CE2   . PHE   D 2 408 ? 210.345 243.643 241.262 1.00 47.80  ? 420 PHE   B CE2   1 
ATOM   3824 C CZ    . PHE   D 2 408 ? 210.466 244.740 240.440 1.00 47.53  ? 420 PHE   B CZ    1 
ATOM   3825 N N     . ASP   D 2 409 ? 206.195 241.796 243.444 1.00 50.07  ? 421 ASP   B N     1 
ATOM   3826 C CA    . ASP   D 2 409 ? 206.507 241.692 244.868 1.00 51.48  ? 421 ASP   B CA    1 
ATOM   3827 C C     . ASP   D 2 409 ? 208.015 241.527 245.018 1.00 50.66  ? 421 ASP   B C     1 
ATOM   3828 O O     . ASP   D 2 409 ? 208.534 240.410 245.029 1.00 51.42  ? 421 ASP   B O     1 
ATOM   3829 C CB    . ASP   D 2 409 ? 205.745 240.534 245.501 1.00 51.22  ? 421 ASP   B CB    1 
ATOM   3830 C CG    . ASP   D 2 409 ? 205.421 240.781 246.955 1.00 55.07  ? 421 ASP   B CG    1 
ATOM   3831 O OD1   . ASP   D 2 409 ? 204.674 241.737 247.242 1.00 56.11  ? 421 ASP   B OD1   1 
ATOM   3832 O OD2   . ASP   D 2 409 ? 205.917 240.021 247.812 1.00 57.41  ? 421 ASP   B OD2   1 
ATOM   3833 N N     . ARG   D 2 410 ? 208.714 242.652 245.155 1.00 48.66  ? 422 ARG   B N     1 
ATOM   3834 C CA    . ARG   D 2 410 ? 210.176 242.636 245.131 1.00 49.19  ? 422 ARG   B CA    1 
ATOM   3835 C C     . ARG   D 2 410 ? 210.803 241.833 246.264 1.00 54.01  ? 422 ARG   B C     1 
ATOM   3836 O O     . ARG   D 2 410 ? 211.725 241.046 245.988 1.00 54.48  ? 422 ARG   B O     1 
ATOM   3837 C CB    . ARG   D 2 410 ? 210.702 244.072 245.118 1.00 50.39  ? 422 ARG   B CB    1 
ATOM   3838 C CG    . ARG   D 2 410 ? 212.001 244.221 244.367 1.00 51.97  ? 422 ARG   B CG    1 
ATOM   3839 C CD    . ARG   D 2 410 ? 212.625 245.571 244.613 1.00 48.19  ? 422 ARG   B CD    1 
ATOM   3840 N NE    . ARG   D 2 410 ? 213.429 245.553 245.826 1.00 47.49  ? 422 ARG   B NE    1 
ATOM   3841 C CZ    . ARG   D 2 410 ? 214.753 245.507 245.843 1.00 54.50  ? 422 ARG   B CZ    1 
ATOM   3842 N NH1   . ARG   D 2 410 ? 215.456 245.465 244.724 1.00 55.07  ? 422 ARG   B NH1   1 
ATOM   3843 N NH2   . ARG   D 2 410 ? 215.386 245.503 247.012 1.00 62.09  ? 422 ARG   B NH2   1 
ATOM   3844 N N     . PRO   D 2 411 ? 210.405 241.987 247.535 1.00 57.17  ? 423 PRO   B N     1 
ATOM   3845 C CA    . PRO   D 2 411 ? 211.069 241.200 248.590 1.00 53.60  ? 423 PRO   B CA    1 
ATOM   3846 C C     . PRO   D 2 411 ? 210.965 239.696 248.400 1.00 51.43  ? 423 PRO   B C     1 
ATOM   3847 O O     . PRO   D 2 411 ? 211.922 238.976 248.704 1.00 49.68  ? 423 PRO   B O     1 
ATOM   3848 C CB    . PRO   D 2 411 ? 210.361 241.666 249.871 1.00 48.47  ? 423 PRO   B CB    1 
ATOM   3849 C CG    . PRO   D 2 411 ? 209.085 242.272 249.410 1.00 50.02  ? 423 PRO   B CG    1 
ATOM   3850 C CD    . PRO   D 2 411 ? 209.419 242.917 248.111 1.00 53.39  ? 423 PRO   B CD    1 
ATOM   3851 N N     . THR   D 2 412 ? 209.832 239.196 247.902 1.00 51.56  ? 424 THR   B N     1 
ATOM   3852 C CA    . THR   D 2 412 ? 209.679 237.752 247.742 1.00 51.44  ? 424 THR   B CA    1 
ATOM   3853 C C     . THR   D 2 412 ? 210.436 237.228 246.528 1.00 51.31  ? 424 THR   B C     1 
ATOM   3854 O O     . THR   D 2 412 ? 210.950 236.104 246.563 1.00 52.61  ? 424 THR   B O     1 
ATOM   3855 C CB    . THR   D 2 412 ? 208.200 237.381 247.641 1.00 52.62  ? 424 THR   B CB    1 
ATOM   3856 O OG1   . THR   D 2 412 ? 207.524 238.332 246.813 1.00 56.57  ? 424 THR   B OG1   1 
ATOM   3857 C CG2   . THR   D 2 412 ? 207.559 237.376 249.015 1.00 52.71  ? 424 THR   B CG2   1 
ATOM   3858 N N     . ILE   D 2 413 ? 210.509 238.008 245.449 1.00 51.46  ? 425 ILE   B N     1 
ATOM   3859 C CA    . ILE   D 2 413 ? 211.238 237.563 244.266 1.00 51.32  ? 425 ILE   B CA    1 
ATOM   3860 C C     . ILE   D 2 413 ? 212.735 237.544 244.535 1.00 53.41  ? 425 ILE   B C     1 
ATOM   3861 O O     . ILE   D 2 413 ? 213.436 236.592 244.174 1.00 53.51  ? 425 ILE   B O     1 
ATOM   3862 C CB    . ILE   D 2 413 ? 210.904 238.451 243.055 1.00 51.16  ? 425 ILE   B CB    1 
ATOM   3863 C CG1   . ILE   D 2 413 ? 209.408 238.410 242.751 1.00 47.88  ? 425 ILE   B CG1   1 
ATOM   3864 C CG2   . ILE   D 2 413 ? 211.690 237.988 241.842 1.00 50.73  ? 425 ILE   B CG2   1 
ATOM   3865 C CD1   . ILE   D 2 413 ? 209.056 238.829 241.345 1.00 49.76  ? 425 ILE   B CD1   1 
ATOM   3866 N N     . MET   D 2 414 ? 213.250 238.598 245.172 1.00 53.17  ? 426 MET   B N     1 
ATOM   3867 C CA    . MET   D 2 414 ? 214.682 238.692 245.410 1.00 52.73  ? 426 MET   B CA    1 
ATOM   3868 C C     . MET   D 2 414 ? 215.130 237.853 246.598 1.00 53.49  ? 426 MET   B C     1 
ATOM   3869 O O     . MET   D 2 414 ? 216.335 237.661 246.784 1.00 57.36  ? 426 MET   B O     1 
ATOM   3870 C CB    . MET   D 2 414 ? 215.084 240.154 245.617 1.00 55.31  ? 426 MET   B CB    1 
ATOM   3871 C CG    . MET   D 2 414 ? 214.692 241.093 244.475 1.00 58.37  ? 426 MET   B CG    1 
ATOM   3872 S SD    . MET   D 2 414 ? 215.444 240.852 242.846 1.00 69.51  ? 426 MET   B SD    1 
ATOM   3873 C CE    . MET   D 2 414 ? 216.948 239.948 243.210 1.00 56.93  ? 426 MET   B CE    1 
ATOM   3874 N N     . ALA   D 2 415 ? 214.192 237.355 247.407 1.00 53.16  ? 427 ALA   B N     1 
ATOM   3875 C CA    . ALA   D 2 415 ? 214.553 236.458 248.498 1.00 53.51  ? 427 ALA   B CA    1 
ATOM   3876 C C     . ALA   D 2 415 ? 215.111 235.137 247.991 1.00 53.93  ? 427 ALA   B C     1 
ATOM   3877 O O     . ALA   D 2 415 ? 215.839 234.462 248.726 1.00 55.38  ? 427 ALA   B O     1 
ATOM   3878 C CB    . ALA   D 2 415 ? 213.342 236.195 249.394 1.00 53.77  ? 427 ALA   B CB    1 
ATOM   3879 N N     . ALA   D 2 416 ? 214.787 234.753 246.756 1.00 50.74  ? 428 ALA   B N     1 
ATOM   3880 C CA    . ALA   D 2 416 ? 215.305 233.515 246.192 1.00 50.22  ? 428 ALA   B CA    1 
ATOM   3881 C C     . ALA   D 2 416 ? 216.801 233.574 245.923 1.00 55.91  ? 428 ALA   B C     1 
ATOM   3882 O O     . ALA   D 2 416 ? 217.417 232.522 245.723 1.00 60.54  ? 428 ALA   B O     1 
ATOM   3883 C CB    . ALA   D 2 416 ? 214.557 233.176 244.902 1.00 48.94  ? 428 ALA   B CB    1 
ATOM   3884 N N     . PHE   D 2 417 ? 217.395 234.763 245.910 1.00 56.70  ? 429 PHE   B N     1 
ATOM   3885 C CA    . PHE   D 2 417 ? 218.837 234.911 245.737 1.00 53.83  ? 429 PHE   B CA    1 
ATOM   3886 C C     . PHE   D 2 417 ? 219.460 235.581 246.957 1.00 50.55  ? 429 PHE   B C     1 
ATOM   3887 O O     . PHE   D 2 417 ? 219.759 234.927 247.955 1.00 45.62  ? 429 PHE   B O     1 
ATOM   3888 C CB    . PHE   D 2 417 ? 219.153 235.720 244.479 1.00 50.98  ? 429 PHE   B CB    1 
ATOM   3889 C CG    . PHE   D 2 417 ? 218.293 235.376 243.297 1.00 54.86  ? 429 PHE   B CG    1 
ATOM   3890 C CD1   . PHE   D 2 417 ? 218.039 234.057 242.961 1.00 58.67  ? 429 PHE   B CD1   1 
ATOM   3891 C CD2   . PHE   D 2 417 ? 217.775 236.374 242.493 1.00 56.23  ? 429 PHE   B CD2   1 
ATOM   3892 C CE1   . PHE   D 2 417 ? 217.256 233.747 241.868 1.00 59.36  ? 429 PHE   B CE1   1 
ATOM   3893 C CE2   . PHE   D 2 417 ? 216.993 236.066 241.401 1.00 51.05  ? 429 PHE   B CE2   1 
ATOM   3894 C CZ    . PHE   D 2 417 ? 216.736 234.754 241.087 1.00 51.30  ? 429 PHE   B CZ    1 
HETATM 3895 C C1    . A1IJK E 3 .   ? 202.363 236.435 214.834 1.00 93.40  ? 101 A1IJK C C1    1 
HETATM 3896 C C2    . A1IJK E 3 .   ? 203.847 236.426 214.563 1.00 102.89 ? 101 A1IJK C C2    1 
HETATM 3897 C C3    . A1IJK E 3 .   ? 204.564 235.351 215.350 1.00 112.47 ? 101 A1IJK C C3    1 
HETATM 3898 C C6    . A1IJK E 3 .   ? 206.667 234.706 216.225 1.00 112.53 ? 101 A1IJK C C6    1 
HETATM 3899 C C7    . A1IJK E 3 .   ? 206.457 233.242 215.897 1.00 111.57 ? 101 A1IJK C C7    1 
HETATM 3900 O O4    . A1IJK E 3 .   ? 205.974 235.533 215.296 1.00 120.55 ? 101 A1IJK C O4    1 
HETATM 3901 O O5    . A1IJK E 3 .   ? 204.386 237.705 214.895 1.00 102.25 ? 101 A1IJK C O5    1 
HETATM 3902 C C8    . A1IJK E 3 .   ? 207.364 232.718 214.797 1.00 112.68 ? 101 A1IJK C C8    1 
HETATM 3903 C C10   . A1IJK E 3 .   ? 207.688 230.308 215.039 1.00 105.70 ? 101 A1IJK C C10   1 
HETATM 3904 N N9    . A1IJK E 3 .   ? 207.058 231.333 214.463 1.00 111.11 ? 101 A1IJK C N9    1 
HETATM 3905 C C33   . A1IJK E 3 .   ? 204.885 226.344 219.083 1.00 119.37 ? 101 A1IJK C C33   1 
HETATM 3906 C C34   . A1IJK E 3 .   ? 205.499 226.365 217.866 1.00 114.73 ? 101 A1IJK C C34   1 
HETATM 3907 C C11   . A1IJK E 3 .   ? 207.188 228.930 214.707 1.00 105.21 ? 101 A1IJK C C11   1 
HETATM 3908 C C12   . A1IJK E 3 .   ? 206.480 228.715 213.534 1.00 105.12 ? 101 A1IJK C C12   1 
HETATM 3909 C C13   . A1IJK E 3 .   ? 206.012 227.454 213.224 1.00 105.21 ? 101 A1IJK C C13   1 
HETATM 3910 C C14   . A1IJK E 3 .   ? 206.210 226.376 214.080 1.00 104.60 ? 101 A1IJK C C14   1 
HETATM 3911 C C15   . A1IJK E 3 .   ? 206.913 226.588 215.285 1.00 106.81 ? 101 A1IJK C C15   1 
HETATM 3912 C C16   . A1IJK E 3 .   ? 207.390 227.864 215.578 1.00 106.56 ? 101 A1IJK C C16   1 
HETATM 3913 C C17   . A1IJK E 3 .   ? 205.649 225.038 213.655 1.00 107.51 ? 101 A1IJK C C17   1 
HETATM 3914 C C20   . A1IJK E 3 .   ? 207.182 225.485 216.260 1.00 110.17 ? 101 A1IJK C C20   1 
HETATM 3915 C C21   . A1IJK E 3 .   ? 208.086 224.376 215.960 1.00 107.19 ? 101 A1IJK C C21   1 
HETATM 3916 C C22   . A1IJK E 3 .   ? 208.322 223.387 216.949 1.00 105.27 ? 101 A1IJK C C22   1 
HETATM 3917 C C24   . A1IJK E 3 .   ? 206.846 224.452 218.492 1.00 112.74 ? 101 A1IJK C C24   1 
HETATM 3918 C C25   . A1IJK E 3 .   ? 206.504 225.449 217.552 1.00 113.07 ? 101 A1IJK C C25   1 
HETATM 3919 C C27   . A1IJK E 3 .   ? 209.154 222.314 216.676 1.00 103.15 ? 101 A1IJK C C27   1 
HETATM 3920 C C28   . A1IJK E 3 .   ? 209.793 222.193 215.386 1.00 105.93 ? 101 A1IJK C C28   1 
HETATM 3921 C C29   . A1IJK E 3 .   ? 209.544 223.213 214.417 1.00 103.81 ? 101 A1IJK C C29   1 
HETATM 3922 C C30   . A1IJK E 3 .   ? 208.713 224.281 214.716 1.00 106.18 ? 101 A1IJK C C30   1 
HETATM 3923 C C31   . A1IJK E 3 .   ? 206.266 224.485 219.755 1.00 114.18 ? 101 A1IJK C C31   1 
HETATM 3924 C C32   . A1IJK E 3 .   ? 205.267 225.455 220.067 1.00 120.02 ? 101 A1IJK C C32   1 
HETATM 3925 O O18   . A1IJK E 3 .   ? 205.550 224.136 214.504 1.00 110.57 ? 101 A1IJK C O18   1 
HETATM 3926 O O19   . A1IJK E 3 .   ? 205.311 224.915 212.465 1.00 106.14 ? 101 A1IJK C O19   1 
HETATM 3927 O O23   . A1IJK E 3 .   ? 207.738 223.454 218.190 1.00 110.29 ? 101 A1IJK C O23   1 
HETATM 3928 O O26   . A1IJK E 3 .   ? 208.634 230.470 215.807 1.00 99.24  ? 101 A1IJK C O26   1 
HETATM 3929 O O35   . A1IJK E 3 .   ? 210.535 221.237 215.130 1.00 115.37 ? 101 A1IJK C O35   1 
HETATM 3930 O O36   . A1IJK E 3 .   ? 204.748 225.492 221.189 1.00 122.57 ? 101 A1IJK C O36   1 
# 
