data_9GA7
# 
_entry.id   9GA7 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9GA7         pdb_00009ga7 10.2210/pdb9ga7/pdb 
WWPDB D_1292140088 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-04 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9GA7 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 alessia.ruggiero@unina.it Alessia Ruggiero   ? 'principal investigator/group leader' 0000-0002-3508-385X 
3 luigi.vitagliano@cnr.it   Luigi   Vitagliano ? 'principal investigator/group leader' 0000-0002-3032-3375 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Vitagliano, L.' 1 ? 
'Barra, G.'      2 ? 
'Ghilardi, O.'   3 ? 
'Di Micco, S.'   4 ? 
'Scala, M.C.'    5 ? 
'Sala, M.'       6 ? 
'Campiglia, P.'  7 ? 
'Bifulco, G.'    8 ? 
'Ruggiero, A.'   9 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Int.J.Biol.Macromol. 
_citation.journal_id_ASTM           IJBMDR 
_citation.journal_id_CSD            0708 
_citation.journal_id_ISSN           0141-8130 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            308 
_citation.language                  ? 
_citation.page_first                142600 
_citation.page_last                 142600 
_citation.title                     
;Computational, crystallographic, and biophysical characterizations provide insights into calcium and phosphate binding by human annexin A4.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.ijbiomac.2025.142600 
_citation.pdbx_database_id_PubMed   40157693 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Di Micco, S.'   1 ? 
primary 'Scala, M.C.'    2 ? 
primary 'Sala, M.'       3 ? 
primary 'Barra, G.'      4 ? 
primary 'Ghilardi, O.'   5 ? 
primary 'Campiglia, P.'  6 ? 
primary 'Bifulco, G.'    7 ? 
primary 'Vitagliano, L.' 8 ? 
primary 'Ruggiero, A.'   9 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Annexin A4'  36760.605 1   ? ? ? ? 
2 non-polymer syn 'CALCIUM ION' 40.078    1   ? ? ? ? 
3 non-polymer syn 'SULFATE ION' 96.063    4   ? ? ? ? 
4 water       nat water         18.015    171 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;35-beta calcimedin,Annexin IV,Annexin-4,Carbohydrate-binding protein p33/p41,Chromobindin-4,Endonexin I,Lipocortin IV,P32.5,PP4-X,Placental anticoagulant protein II,PAP-II,Protein II
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MATKGGTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSELSGNFEQVI
VGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGR
DEGNYLDDALVRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIV
KCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDDH
HHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MATKGGTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSELSGNFEQVI
VGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGR
DEGNYLDDALVRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIV
KCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDDH
HHHHH
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'CALCIUM ION' CA  
3 'SULFATE ION' SO4 
4 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   THR n 
1 4   LYS n 
1 5   GLY n 
1 6   GLY n 
1 7   THR n 
1 8   VAL n 
1 9   LYS n 
1 10  ALA n 
1 11  ALA n 
1 12  SER n 
1 13  GLY n 
1 14  PHE n 
1 15  ASN n 
1 16  ALA n 
1 17  MET n 
1 18  GLU n 
1 19  ASP n 
1 20  ALA n 
1 21  GLN n 
1 22  THR n 
1 23  LEU n 
1 24  ARG n 
1 25  LYS n 
1 26  ALA n 
1 27  MET n 
1 28  LYS n 
1 29  GLY n 
1 30  LEU n 
1 31  GLY n 
1 32  THR n 
1 33  ASP n 
1 34  GLU n 
1 35  ASP n 
1 36  ALA n 
1 37  ILE n 
1 38  ILE n 
1 39  SER n 
1 40  VAL n 
1 41  LEU n 
1 42  ALA n 
1 43  TYR n 
1 44  ARG n 
1 45  ASN n 
1 46  THR n 
1 47  ALA n 
1 48  GLN n 
1 49  ARG n 
1 50  GLN n 
1 51  GLU n 
1 52  ILE n 
1 53  ARG n 
1 54  THR n 
1 55  ALA n 
1 56  TYR n 
1 57  LYS n 
1 58  SER n 
1 59  THR n 
1 60  ILE n 
1 61  GLY n 
1 62  ARG n 
1 63  ASP n 
1 64  LEU n 
1 65  ILE n 
1 66  ASP n 
1 67  ASP n 
1 68  LEU n 
1 69  LYS n 
1 70  SER n 
1 71  GLU n 
1 72  LEU n 
1 73  SER n 
1 74  GLY n 
1 75  ASN n 
1 76  PHE n 
1 77  GLU n 
1 78  GLN n 
1 79  VAL n 
1 80  ILE n 
1 81  VAL n 
1 82  GLY n 
1 83  MET n 
1 84  MET n 
1 85  THR n 
1 86  PRO n 
1 87  THR n 
1 88  VAL n 
1 89  LEU n 
1 90  TYR n 
1 91  ASP n 
1 92  VAL n 
1 93  GLN n 
1 94  GLU n 
1 95  LEU n 
1 96  ARG n 
1 97  ARG n 
1 98  ALA n 
1 99  MET n 
1 100 LYS n 
1 101 GLY n 
1 102 ALA n 
1 103 GLY n 
1 104 THR n 
1 105 ASP n 
1 106 GLU n 
1 107 GLY n 
1 108 CYS n 
1 109 LEU n 
1 110 ILE n 
1 111 GLU n 
1 112 ILE n 
1 113 LEU n 
1 114 ALA n 
1 115 SER n 
1 116 ARG n 
1 117 THR n 
1 118 PRO n 
1 119 GLU n 
1 120 GLU n 
1 121 ILE n 
1 122 ARG n 
1 123 ARG n 
1 124 ILE n 
1 125 SER n 
1 126 GLN n 
1 127 THR n 
1 128 TYR n 
1 129 GLN n 
1 130 GLN n 
1 131 GLN n 
1 132 TYR n 
1 133 GLY n 
1 134 ARG n 
1 135 SER n 
1 136 LEU n 
1 137 GLU n 
1 138 ASP n 
1 139 ASP n 
1 140 ILE n 
1 141 ARG n 
1 142 SER n 
1 143 ASP n 
1 144 THR n 
1 145 SER n 
1 146 PHE n 
1 147 MET n 
1 148 PHE n 
1 149 GLN n 
1 150 ARG n 
1 151 VAL n 
1 152 LEU n 
1 153 VAL n 
1 154 SER n 
1 155 LEU n 
1 156 SER n 
1 157 ALA n 
1 158 GLY n 
1 159 GLY n 
1 160 ARG n 
1 161 ASP n 
1 162 GLU n 
1 163 GLY n 
1 164 ASN n 
1 165 TYR n 
1 166 LEU n 
1 167 ASP n 
1 168 ASP n 
1 169 ALA n 
1 170 LEU n 
1 171 VAL n 
1 172 ARG n 
1 173 GLN n 
1 174 ASP n 
1 175 ALA n 
1 176 GLN n 
1 177 ASP n 
1 178 LEU n 
1 179 TYR n 
1 180 GLU n 
1 181 ALA n 
1 182 GLY n 
1 183 GLU n 
1 184 LYS n 
1 185 LYS n 
1 186 TRP n 
1 187 GLY n 
1 188 THR n 
1 189 ASP n 
1 190 GLU n 
1 191 VAL n 
1 192 LYS n 
1 193 PHE n 
1 194 LEU n 
1 195 THR n 
1 196 VAL n 
1 197 LEU n 
1 198 CYS n 
1 199 SER n 
1 200 ARG n 
1 201 ASN n 
1 202 ARG n 
1 203 ASN n 
1 204 HIS n 
1 205 LEU n 
1 206 LEU n 
1 207 HIS n 
1 208 VAL n 
1 209 PHE n 
1 210 ASP n 
1 211 GLU n 
1 212 TYR n 
1 213 LYS n 
1 214 ARG n 
1 215 ILE n 
1 216 SER n 
1 217 GLN n 
1 218 LYS n 
1 219 ASP n 
1 220 ILE n 
1 221 GLU n 
1 222 GLN n 
1 223 SER n 
1 224 ILE n 
1 225 LYS n 
1 226 SER n 
1 227 GLU n 
1 228 THR n 
1 229 SER n 
1 230 GLY n 
1 231 SER n 
1 232 PHE n 
1 233 GLU n 
1 234 ASP n 
1 235 ALA n 
1 236 LEU n 
1 237 LEU n 
1 238 ALA n 
1 239 ILE n 
1 240 VAL n 
1 241 LYS n 
1 242 CYS n 
1 243 MET n 
1 244 ARG n 
1 245 ASN n 
1 246 LYS n 
1 247 SER n 
1 248 ALA n 
1 249 TYR n 
1 250 PHE n 
1 251 ALA n 
1 252 GLU n 
1 253 LYS n 
1 254 LEU n 
1 255 TYR n 
1 256 LYS n 
1 257 SER n 
1 258 MET n 
1 259 LYS n 
1 260 GLY n 
1 261 LEU n 
1 262 GLY n 
1 263 THR n 
1 264 ASP n 
1 265 ASP n 
1 266 ASN n 
1 267 THR n 
1 268 LEU n 
1 269 ILE n 
1 270 ARG n 
1 271 VAL n 
1 272 MET n 
1 273 VAL n 
1 274 SER n 
1 275 ARG n 
1 276 ALA n 
1 277 GLU n 
1 278 ILE n 
1 279 ASP n 
1 280 MET n 
1 281 LEU n 
1 282 ASP n 
1 283 ILE n 
1 284 ARG n 
1 285 ALA n 
1 286 HIS n 
1 287 PHE n 
1 288 LYS n 
1 289 ARG n 
1 290 LEU n 
1 291 TYR n 
1 292 GLY n 
1 293 LYS n 
1 294 SER n 
1 295 LEU n 
1 296 TYR n 
1 297 SER n 
1 298 PHE n 
1 299 ILE n 
1 300 LYS n 
1 301 GLY n 
1 302 ASP n 
1 303 THR n 
1 304 SER n 
1 305 GLY n 
1 306 ASP n 
1 307 TYR n 
1 308 ARG n 
1 309 LYS n 
1 310 VAL n 
1 311 LEU n 
1 312 LEU n 
1 313 VAL n 
1 314 LEU n 
1 315 CYS n 
1 316 GLY n 
1 317 GLY n 
1 318 ASP n 
1 319 ASP n 
1 320 HIS n 
1 321 HIS n 
1 322 HIS n 
1 323 HIS n 
1 324 HIS n 
1 325 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   325 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'ANXA4, ANX4' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CA  non-polymer         . 'CALCIUM ION'   ? 'Ca 2'           40.078  
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   THR 3   3   3   THR THR A . n 
A 1 4   LYS 4   4   4   LYS LYS A . n 
A 1 5   GLY 5   5   5   GLY GLY A . n 
A 1 6   GLY 6   6   6   GLY GLY A . n 
A 1 7   THR 7   7   7   THR THR A . n 
A 1 8   VAL 8   8   8   VAL VAL A . n 
A 1 9   LYS 9   9   9   LYS LYS A . n 
A 1 10  ALA 10  10  10  ALA ALA A . n 
A 1 11  ALA 11  11  11  ALA ALA A . n 
A 1 12  SER 12  12  12  SER SER A . n 
A 1 13  GLY 13  13  13  GLY GLY A . n 
A 1 14  PHE 14  14  14  PHE PHE A . n 
A 1 15  ASN 15  15  15  ASN ASN A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  MET 17  17  17  MET MET A . n 
A 1 18  GLU 18  18  18  GLU GLU A . n 
A 1 19  ASP 19  19  19  ASP ASP A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  GLN 21  21  21  GLN GLN A . n 
A 1 22  THR 22  22  22  THR THR A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  ARG 24  24  24  ARG ARG A . n 
A 1 25  LYS 25  25  25  LYS LYS A . n 
A 1 26  ALA 26  26  26  ALA ALA A . n 
A 1 27  MET 27  27  27  MET MET A . n 
A 1 28  LYS 28  28  28  LYS LYS A . n 
A 1 29  GLY 29  29  29  GLY GLY A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  ASP 33  33  33  ASP ASP A . n 
A 1 34  GLU 34  34  34  GLU GLU A . n 
A 1 35  ASP 35  35  35  ASP ASP A . n 
A 1 36  ALA 36  36  36  ALA ALA A . n 
A 1 37  ILE 37  37  37  ILE ILE A . n 
A 1 38  ILE 38  38  38  ILE ILE A . n 
A 1 39  SER 39  39  39  SER SER A . n 
A 1 40  VAL 40  40  40  VAL VAL A . n 
A 1 41  LEU 41  41  41  LEU LEU A . n 
A 1 42  ALA 42  42  42  ALA ALA A . n 
A 1 43  TYR 43  43  43  TYR TYR A . n 
A 1 44  ARG 44  44  44  ARG ARG A . n 
A 1 45  ASN 45  45  45  ASN ASN A . n 
A 1 46  THR 46  46  46  THR THR A . n 
A 1 47  ALA 47  47  47  ALA ALA A . n 
A 1 48  GLN 48  48  48  GLN GLN A . n 
A 1 49  ARG 49  49  49  ARG ARG A . n 
A 1 50  GLN 50  50  50  GLN GLN A . n 
A 1 51  GLU 51  51  51  GLU GLU A . n 
A 1 52  ILE 52  52  52  ILE ILE A . n 
A 1 53  ARG 53  53  53  ARG ARG A . n 
A 1 54  THR 54  54  54  THR THR A . n 
A 1 55  ALA 55  55  55  ALA ALA A . n 
A 1 56  TYR 56  56  56  TYR TYR A . n 
A 1 57  LYS 57  57  57  LYS LYS A . n 
A 1 58  SER 58  58  58  SER SER A . n 
A 1 59  THR 59  59  59  THR THR A . n 
A 1 60  ILE 60  60  60  ILE ILE A . n 
A 1 61  GLY 61  61  61  GLY GLY A . n 
A 1 62  ARG 62  62  62  ARG ARG A . n 
A 1 63  ASP 63  63  63  ASP ASP A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  ILE 65  65  65  ILE ILE A . n 
A 1 66  ASP 66  66  66  ASP ASP A . n 
A 1 67  ASP 67  67  67  ASP ASP A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  LYS 69  69  69  LYS LYS A . n 
A 1 70  SER 70  70  70  SER SER A . n 
A 1 71  GLU 71  71  71  GLU GLU A . n 
A 1 72  LEU 72  72  72  LEU LEU A . n 
A 1 73  SER 73  73  73  SER SER A . n 
A 1 74  GLY 74  74  74  GLY GLY A . n 
A 1 75  ASN 75  75  75  ASN ASN A . n 
A 1 76  PHE 76  76  76  PHE PHE A . n 
A 1 77  GLU 77  77  77  GLU GLU A . n 
A 1 78  GLN 78  78  78  GLN GLN A . n 
A 1 79  VAL 79  79  79  VAL VAL A . n 
A 1 80  ILE 80  80  80  ILE ILE A . n 
A 1 81  VAL 81  81  81  VAL VAL A . n 
A 1 82  GLY 82  82  82  GLY GLY A . n 
A 1 83  MET 83  83  83  MET MET A . n 
A 1 84  MET 84  84  84  MET MET A . n 
A 1 85  THR 85  85  85  THR THR A . n 
A 1 86  PRO 86  86  86  PRO PRO A . n 
A 1 87  THR 87  87  87  THR THR A . n 
A 1 88  VAL 88  88  88  VAL VAL A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  TYR 90  90  90  TYR TYR A . n 
A 1 91  ASP 91  91  91  ASP ASP A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  GLN 93  93  93  GLN GLN A . n 
A 1 94  GLU 94  94  94  GLU GLU A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  ARG 96  96  96  ARG ARG A . n 
A 1 97  ARG 97  97  97  ARG ARG A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  MET 99  99  99  MET MET A . n 
A 1 100 LYS 100 100 100 LYS LYS A . n 
A 1 101 GLY 101 101 101 GLY GLY A . n 
A 1 102 ALA 102 102 102 ALA ALA A . n 
A 1 103 GLY 103 103 103 GLY GLY A . n 
A 1 104 THR 104 104 104 THR THR A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 GLU 106 106 106 GLU GLU A . n 
A 1 107 GLY 107 107 107 GLY GLY A . n 
A 1 108 CYS 108 108 108 CYS CYS A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 ILE 110 110 110 ILE ILE A . n 
A 1 111 GLU 111 111 111 GLU GLU A . n 
A 1 112 ILE 112 112 112 ILE ILE A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 ALA 114 114 114 ALA ALA A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 ARG 116 116 116 ARG ARG A . n 
A 1 117 THR 117 117 117 THR THR A . n 
A 1 118 PRO 118 118 118 PRO PRO A . n 
A 1 119 GLU 119 119 119 GLU GLU A . n 
A 1 120 GLU 120 120 120 GLU GLU A . n 
A 1 121 ILE 121 121 121 ILE ILE A . n 
A 1 122 ARG 122 122 122 ARG ARG A . n 
A 1 123 ARG 123 123 123 ARG ARG A . n 
A 1 124 ILE 124 124 124 ILE ILE A . n 
A 1 125 SER 125 125 125 SER SER A . n 
A 1 126 GLN 126 126 126 GLN GLN A . n 
A 1 127 THR 127 127 127 THR THR A . n 
A 1 128 TYR 128 128 128 TYR TYR A . n 
A 1 129 GLN 129 129 129 GLN GLN A . n 
A 1 130 GLN 130 130 130 GLN GLN A . n 
A 1 131 GLN 131 131 131 GLN GLN A . n 
A 1 132 TYR 132 132 132 TYR TYR A . n 
A 1 133 GLY 133 133 133 GLY GLY A . n 
A 1 134 ARG 134 134 134 ARG ARG A . n 
A 1 135 SER 135 135 135 SER SER A . n 
A 1 136 LEU 136 136 136 LEU LEU A . n 
A 1 137 GLU 137 137 137 GLU GLU A . n 
A 1 138 ASP 138 138 138 ASP ASP A . n 
A 1 139 ASP 139 139 139 ASP ASP A . n 
A 1 140 ILE 140 140 140 ILE ILE A . n 
A 1 141 ARG 141 141 141 ARG ARG A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 ASP 143 143 143 ASP ASP A . n 
A 1 144 THR 144 144 144 THR THR A . n 
A 1 145 SER 145 145 145 SER SER A . n 
A 1 146 PHE 146 146 146 PHE PHE A . n 
A 1 147 MET 147 147 147 MET MET A . n 
A 1 148 PHE 148 148 148 PHE PHE A . n 
A 1 149 GLN 149 149 149 GLN GLN A . n 
A 1 150 ARG 150 150 150 ARG ARG A . n 
A 1 151 VAL 151 151 151 VAL VAL A . n 
A 1 152 LEU 152 152 152 LEU LEU A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 SER 154 154 154 SER SER A . n 
A 1 155 LEU 155 155 155 LEU LEU A . n 
A 1 156 SER 156 156 156 SER SER A . n 
A 1 157 ALA 157 157 157 ALA ALA A . n 
A 1 158 GLY 158 158 158 GLY GLY A . n 
A 1 159 GLY 159 159 159 GLY GLY A . n 
A 1 160 ARG 160 160 160 ARG ARG A . n 
A 1 161 ASP 161 161 161 ASP ASP A . n 
A 1 162 GLU 162 162 162 GLU GLU A . n 
A 1 163 GLY 163 163 163 GLY GLY A . n 
A 1 164 ASN 164 164 164 ASN ASN A . n 
A 1 165 TYR 165 165 165 TYR TYR A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 ASP 167 167 167 ASP ASP A . n 
A 1 168 ASP 168 168 168 ASP ASP A . n 
A 1 169 ALA 169 169 169 ALA ALA A . n 
A 1 170 LEU 170 170 170 LEU LEU A . n 
A 1 171 VAL 171 171 171 VAL VAL A . n 
A 1 172 ARG 172 172 172 ARG ARG A . n 
A 1 173 GLN 173 173 173 GLN GLN A . n 
A 1 174 ASP 174 174 174 ASP ASP A . n 
A 1 175 ALA 175 175 175 ALA ALA A . n 
A 1 176 GLN 176 176 176 GLN GLN A . n 
A 1 177 ASP 177 177 177 ASP ASP A . n 
A 1 178 LEU 178 178 178 LEU LEU A . n 
A 1 179 TYR 179 179 179 TYR TYR A . n 
A 1 180 GLU 180 180 180 GLU GLU A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 GLY 182 182 182 GLY GLY A . n 
A 1 183 GLU 183 183 183 GLU GLU A . n 
A 1 184 LYS 184 184 184 LYS LYS A . n 
A 1 185 LYS 185 185 185 LYS LYS A . n 
A 1 186 TRP 186 186 186 TRP TRP A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 THR 188 188 188 THR THR A . n 
A 1 189 ASP 189 189 189 ASP ASP A . n 
A 1 190 GLU 190 190 190 GLU GLU A . n 
A 1 191 VAL 191 191 191 VAL VAL A . n 
A 1 192 LYS 192 192 192 LYS LYS A . n 
A 1 193 PHE 193 193 193 PHE PHE A . n 
A 1 194 LEU 194 194 194 LEU LEU A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 VAL 196 196 196 VAL VAL A . n 
A 1 197 LEU 197 197 197 LEU LEU A . n 
A 1 198 CYS 198 198 198 CYS CYS A . n 
A 1 199 SER 199 199 199 SER SER A . n 
A 1 200 ARG 200 200 200 ARG ARG A . n 
A 1 201 ASN 201 201 201 ASN ASN A . n 
A 1 202 ARG 202 202 202 ARG ARG A . n 
A 1 203 ASN 203 203 203 ASN ASN A . n 
A 1 204 HIS 204 204 204 HIS HIS A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 LEU 206 206 206 LEU LEU A . n 
A 1 207 HIS 207 207 207 HIS HIS A . n 
A 1 208 VAL 208 208 208 VAL VAL A . n 
A 1 209 PHE 209 209 209 PHE PHE A . n 
A 1 210 ASP 210 210 210 ASP ASP A . n 
A 1 211 GLU 211 211 211 GLU GLU A . n 
A 1 212 TYR 212 212 212 TYR TYR A . n 
A 1 213 LYS 213 213 213 LYS LYS A . n 
A 1 214 ARG 214 214 214 ARG ARG A . n 
A 1 215 ILE 215 215 215 ILE ILE A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 GLN 217 217 217 GLN GLN A . n 
A 1 218 LYS 218 218 218 LYS LYS A . n 
A 1 219 ASP 219 219 219 ASP ASP A . n 
A 1 220 ILE 220 220 220 ILE ILE A . n 
A 1 221 GLU 221 221 221 GLU GLU A . n 
A 1 222 GLN 222 222 222 GLN GLN A . n 
A 1 223 SER 223 223 223 SER SER A . n 
A 1 224 ILE 224 224 224 ILE ILE A . n 
A 1 225 LYS 225 225 225 LYS LYS A . n 
A 1 226 SER 226 226 226 SER SER A . n 
A 1 227 GLU 227 227 227 GLU GLU A . n 
A 1 228 THR 228 228 228 THR THR A . n 
A 1 229 SER 229 229 229 SER SER A . n 
A 1 230 GLY 230 230 230 GLY GLY A . n 
A 1 231 SER 231 231 231 SER SER A . n 
A 1 232 PHE 232 232 232 PHE PHE A . n 
A 1 233 GLU 233 233 233 GLU GLU A . n 
A 1 234 ASP 234 234 234 ASP ASP A . n 
A 1 235 ALA 235 235 235 ALA ALA A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 LEU 237 237 237 LEU LEU A . n 
A 1 238 ALA 238 238 238 ALA ALA A . n 
A 1 239 ILE 239 239 239 ILE ILE A . n 
A 1 240 VAL 240 240 240 VAL VAL A . n 
A 1 241 LYS 241 241 241 LYS LYS A . n 
A 1 242 CYS 242 242 242 CYS CYS A . n 
A 1 243 MET 243 243 243 MET MET A . n 
A 1 244 ARG 244 244 244 ARG ARG A . n 
A 1 245 ASN 245 245 245 ASN ASN A . n 
A 1 246 LYS 246 246 246 LYS LYS A . n 
A 1 247 SER 247 247 247 SER SER A . n 
A 1 248 ALA 248 248 248 ALA ALA A . n 
A 1 249 TYR 249 249 249 TYR TYR A . n 
A 1 250 PHE 250 250 250 PHE PHE A . n 
A 1 251 ALA 251 251 251 ALA ALA A . n 
A 1 252 GLU 252 252 252 GLU GLU A . n 
A 1 253 LYS 253 253 253 LYS LYS A . n 
A 1 254 LEU 254 254 254 LEU LEU A . n 
A 1 255 TYR 255 255 255 TYR TYR A . n 
A 1 256 LYS 256 256 256 LYS LYS A . n 
A 1 257 SER 257 257 257 SER SER A . n 
A 1 258 MET 258 258 258 MET MET A . n 
A 1 259 LYS 259 259 259 LYS LYS A . n 
A 1 260 GLY 260 260 260 GLY GLY A . n 
A 1 261 LEU 261 261 261 LEU LEU A . n 
A 1 262 GLY 262 262 262 GLY GLY A . n 
A 1 263 THR 263 263 263 THR THR A . n 
A 1 264 ASP 264 264 264 ASP ASP A . n 
A 1 265 ASP 265 265 265 ASP ASP A . n 
A 1 266 ASN 266 266 266 ASN ASN A . n 
A 1 267 THR 267 267 267 THR THR A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 ARG 270 270 270 ARG ARG A . n 
A 1 271 VAL 271 271 271 VAL VAL A . n 
A 1 272 MET 272 272 272 MET MET A . n 
A 1 273 VAL 273 273 273 VAL VAL A . n 
A 1 274 SER 274 274 274 SER SER A . n 
A 1 275 ARG 275 275 275 ARG ARG A . n 
A 1 276 ALA 276 276 276 ALA ALA A . n 
A 1 277 GLU 277 277 277 GLU GLU A . n 
A 1 278 ILE 278 278 278 ILE ILE A . n 
A 1 279 ASP 279 279 279 ASP ASP A . n 
A 1 280 MET 280 280 280 MET MET A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 ASP 282 282 282 ASP ASP A . n 
A 1 283 ILE 283 283 283 ILE ILE A . n 
A 1 284 ARG 284 284 284 ARG ARG A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 HIS 286 286 286 HIS HIS A . n 
A 1 287 PHE 287 287 287 PHE PHE A . n 
A 1 288 LYS 288 288 288 LYS LYS A . n 
A 1 289 ARG 289 289 289 ARG ARG A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 TYR 291 291 291 TYR TYR A . n 
A 1 292 GLY 292 292 292 GLY GLY A . n 
A 1 293 LYS 293 293 293 LYS LYS A . n 
A 1 294 SER 294 294 294 SER SER A . n 
A 1 295 LEU 295 295 295 LEU LEU A . n 
A 1 296 TYR 296 296 296 TYR TYR A . n 
A 1 297 SER 297 297 297 SER SER A . n 
A 1 298 PHE 298 298 298 PHE PHE A . n 
A 1 299 ILE 299 299 299 ILE ILE A . n 
A 1 300 LYS 300 300 300 LYS LYS A . n 
A 1 301 GLY 301 301 301 GLY GLY A . n 
A 1 302 ASP 302 302 302 ASP ASP A . n 
A 1 303 THR 303 303 303 THR THR A . n 
A 1 304 SER 304 304 304 SER SER A . n 
A 1 305 GLY 305 305 305 GLY GLY A . n 
A 1 306 ASP 306 306 306 ASP ASP A . n 
A 1 307 TYR 307 307 307 TYR TYR A . n 
A 1 308 ARG 308 308 308 ARG ARG A . n 
A 1 309 LYS 309 309 309 LYS LYS A . n 
A 1 310 VAL 310 310 310 VAL VAL A . n 
A 1 311 LEU 311 311 311 LEU LEU A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 VAL 313 313 313 VAL VAL A . n 
A 1 314 LEU 314 314 314 LEU LEU A . n 
A 1 315 CYS 315 315 315 CYS CYS A . n 
A 1 316 GLY 316 316 316 GLY GLY A . n 
A 1 317 GLY 317 317 ?   ?   ?   A . n 
A 1 318 ASP 318 318 ?   ?   ?   A . n 
A 1 319 ASP 319 319 ?   ?   ?   A . n 
A 1 320 HIS 320 320 ?   ?   ?   A . n 
A 1 321 HIS 321 321 ?   ?   ?   A . n 
A 1 322 HIS 322 322 ?   ?   ?   A . n 
A 1 323 HIS 323 323 ?   ?   ?   A . n 
A 1 324 HIS 324 324 ?   ?   ?   A . n 
A 1 325 HIS 325 325 ?   ?   ?   A . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 CA  ? ? CA  ? ? 'SUBJECT OF INVESTIGATION' ? 
2 SO4 ? ? SO4 ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 CA  1   401 1   CA  CA  A . 
C 3 SO4 1   402 239 SO4 SO4 A . 
D 3 SO4 1   403 240 SO4 SO4 A . 
E 3 SO4 1   404 241 SO4 SO4 A . 
F 3 SO4 1   405 242 SO4 SO4 A . 
G 4 HOH 1   501 17  HOH HOH A . 
G 4 HOH 2   502 171 HOH HOH A . 
G 4 HOH 3   503 159 HOH HOH A . 
G 4 HOH 4   504 8   HOH HOH A . 
G 4 HOH 5   505 110 HOH HOH A . 
G 4 HOH 6   506 45  HOH HOH A . 
G 4 HOH 7   507 118 HOH HOH A . 
G 4 HOH 8   508 50  HOH HOH A . 
G 4 HOH 9   509 140 HOH HOH A . 
G 4 HOH 10  510 154 HOH HOH A . 
G 4 HOH 11  511 176 HOH HOH A . 
G 4 HOH 12  512 89  HOH HOH A . 
G 4 HOH 13  513 21  HOH HOH A . 
G 4 HOH 14  514 43  HOH HOH A . 
G 4 HOH 15  515 177 HOH HOH A . 
G 4 HOH 16  516 117 HOH HOH A . 
G 4 HOH 17  517 161 HOH HOH A . 
G 4 HOH 18  518 111 HOH HOH A . 
G 4 HOH 19  519 149 HOH HOH A . 
G 4 HOH 20  520 101 HOH HOH A . 
G 4 HOH 21  521 143 HOH HOH A . 
G 4 HOH 22  522 22  HOH HOH A . 
G 4 HOH 23  523 84  HOH HOH A . 
G 4 HOH 24  524 172 HOH HOH A . 
G 4 HOH 25  525 103 HOH HOH A . 
G 4 HOH 26  526 173 HOH HOH A . 
G 4 HOH 27  527 168 HOH HOH A . 
G 4 HOH 28  528 6   HOH HOH A . 
G 4 HOH 29  529 123 HOH HOH A . 
G 4 HOH 30  530 75  HOH HOH A . 
G 4 HOH 31  531 175 HOH HOH A . 
G 4 HOH 32  532 54  HOH HOH A . 
G 4 HOH 33  533 38  HOH HOH A . 
G 4 HOH 34  534 26  HOH HOH A . 
G 4 HOH 35  535 102 HOH HOH A . 
G 4 HOH 36  536 83  HOH HOH A . 
G 4 HOH 37  537 73  HOH HOH A . 
G 4 HOH 38  538 87  HOH HOH A . 
G 4 HOH 39  539 25  HOH HOH A . 
G 4 HOH 40  540 1   HOH HOH A . 
G 4 HOH 41  541 158 HOH HOH A . 
G 4 HOH 42  542 76  HOH HOH A . 
G 4 HOH 43  543 35  HOH HOH A . 
G 4 HOH 44  544 133 HOH HOH A . 
G 4 HOH 45  545 150 HOH HOH A . 
G 4 HOH 46  546 56  HOH HOH A . 
G 4 HOH 47  547 28  HOH HOH A . 
G 4 HOH 48  548 12  HOH HOH A . 
G 4 HOH 49  549 2   HOH HOH A . 
G 4 HOH 50  550 98  HOH HOH A . 
G 4 HOH 51  551 48  HOH HOH A . 
G 4 HOH 52  552 155 HOH HOH A . 
G 4 HOH 53  553 4   HOH HOH A . 
G 4 HOH 54  554 31  HOH HOH A . 
G 4 HOH 55  555 78  HOH HOH A . 
G 4 HOH 56  556 29  HOH HOH A . 
G 4 HOH 57  557 128 HOH HOH A . 
G 4 HOH 58  558 119 HOH HOH A . 
G 4 HOH 59  559 90  HOH HOH A . 
G 4 HOH 60  560 81  HOH HOH A . 
G 4 HOH 61  561 13  HOH HOH A . 
G 4 HOH 62  562 146 HOH HOH A . 
G 4 HOH 63  563 178 HOH HOH A . 
G 4 HOH 64  564 94  HOH HOH A . 
G 4 HOH 65  565 42  HOH HOH A . 
G 4 HOH 66  566 124 HOH HOH A . 
G 4 HOH 67  567 15  HOH HOH A . 
G 4 HOH 68  568 41  HOH HOH A . 
G 4 HOH 69  569 52  HOH HOH A . 
G 4 HOH 70  570 34  HOH HOH A . 
G 4 HOH 71  571 93  HOH HOH A . 
G 4 HOH 72  572 79  HOH HOH A . 
G 4 HOH 73  573 74  HOH HOH A . 
G 4 HOH 74  574 51  HOH HOH A . 
G 4 HOH 75  575 134 HOH HOH A . 
G 4 HOH 76  576 144 HOH HOH A . 
G 4 HOH 77  577 23  HOH HOH A . 
G 4 HOH 78  578 162 HOH HOH A . 
G 4 HOH 79  579 3   HOH HOH A . 
G 4 HOH 80  580 63  HOH HOH A . 
G 4 HOH 81  581 88  HOH HOH A . 
G 4 HOH 82  582 19  HOH HOH A . 
G 4 HOH 83  583 40  HOH HOH A . 
G 4 HOH 84  584 126 HOH HOH A . 
G 4 HOH 85  585 16  HOH HOH A . 
G 4 HOH 86  586 24  HOH HOH A . 
G 4 HOH 87  587 68  HOH HOH A . 
G 4 HOH 88  588 57  HOH HOH A . 
G 4 HOH 89  589 47  HOH HOH A . 
G 4 HOH 90  590 91  HOH HOH A . 
G 4 HOH 91  591 166 HOH HOH A . 
G 4 HOH 92  592 104 HOH HOH A . 
G 4 HOH 93  593 55  HOH HOH A . 
G 4 HOH 94  594 120 HOH HOH A . 
G 4 HOH 95  595 53  HOH HOH A . 
G 4 HOH 96  596 65  HOH HOH A . 
G 4 HOH 97  597 67  HOH HOH A . 
G 4 HOH 98  598 11  HOH HOH A . 
G 4 HOH 99  599 37  HOH HOH A . 
G 4 HOH 100 600 9   HOH HOH A . 
G 4 HOH 101 601 135 HOH HOH A . 
G 4 HOH 102 602 36  HOH HOH A . 
G 4 HOH 103 603 69  HOH HOH A . 
G 4 HOH 104 604 108 HOH HOH A . 
G 4 HOH 105 605 145 HOH HOH A . 
G 4 HOH 106 606 106 HOH HOH A . 
G 4 HOH 107 607 164 HOH HOH A . 
G 4 HOH 108 608 112 HOH HOH A . 
G 4 HOH 109 609 5   HOH HOH A . 
G 4 HOH 110 610 72  HOH HOH A . 
G 4 HOH 111 611 147 HOH HOH A . 
G 4 HOH 112 612 142 HOH HOH A . 
G 4 HOH 113 613 139 HOH HOH A . 
G 4 HOH 114 614 49  HOH HOH A . 
G 4 HOH 115 615 99  HOH HOH A . 
G 4 HOH 116 616 151 HOH HOH A . 
G 4 HOH 117 617 64  HOH HOH A . 
G 4 HOH 118 618 97  HOH HOH A . 
G 4 HOH 119 619 77  HOH HOH A . 
G 4 HOH 120 620 136 HOH HOH A . 
G 4 HOH 121 621 27  HOH HOH A . 
G 4 HOH 122 622 122 HOH HOH A . 
G 4 HOH 123 623 46  HOH HOH A . 
G 4 HOH 124 624 10  HOH HOH A . 
G 4 HOH 125 625 30  HOH HOH A . 
G 4 HOH 126 626 59  HOH HOH A . 
G 4 HOH 127 627 86  HOH HOH A . 
G 4 HOH 128 628 58  HOH HOH A . 
G 4 HOH 129 629 137 HOH HOH A . 
G 4 HOH 130 630 179 HOH HOH A . 
G 4 HOH 131 631 70  HOH HOH A . 
G 4 HOH 132 632 39  HOH HOH A . 
G 4 HOH 133 633 121 HOH HOH A . 
G 4 HOH 134 634 85  HOH HOH A . 
G 4 HOH 135 635 109 HOH HOH A . 
G 4 HOH 136 636 156 HOH HOH A . 
G 4 HOH 137 637 95  HOH HOH A . 
G 4 HOH 138 638 115 HOH HOH A . 
G 4 HOH 139 639 141 HOH HOH A . 
G 4 HOH 140 640 71  HOH HOH A . 
G 4 HOH 141 641 100 HOH HOH A . 
G 4 HOH 142 642 113 HOH HOH A . 
G 4 HOH 143 643 116 HOH HOH A . 
G 4 HOH 144 644 14  HOH HOH A . 
G 4 HOH 145 645 18  HOH HOH A . 
G 4 HOH 146 646 105 HOH HOH A . 
G 4 HOH 147 647 66  HOH HOH A . 
G 4 HOH 148 648 44  HOH HOH A . 
G 4 HOH 149 649 80  HOH HOH A . 
G 4 HOH 150 650 60  HOH HOH A . 
G 4 HOH 151 651 131 HOH HOH A . 
G 4 HOH 152 652 61  HOH HOH A . 
G 4 HOH 153 653 32  HOH HOH A . 
G 4 HOH 154 654 170 HOH HOH A . 
G 4 HOH 155 655 127 HOH HOH A . 
G 4 HOH 156 656 129 HOH HOH A . 
G 4 HOH 157 657 148 HOH HOH A . 
G 4 HOH 158 658 160 HOH HOH A . 
G 4 HOH 159 659 92  HOH HOH A . 
G 4 HOH 160 660 152 HOH HOH A . 
G 4 HOH 161 661 130 HOH HOH A . 
G 4 HOH 162 662 125 HOH HOH A . 
G 4 HOH 163 663 96  HOH HOH A . 
G 4 HOH 164 664 138 HOH HOH A . 
G 4 HOH 165 665 163 HOH HOH A . 
G 4 HOH 166 666 82  HOH HOH A . 
G 4 HOH 167 667 114 HOH HOH A . 
G 4 HOH 168 668 153 HOH HOH A . 
G 4 HOH 169 669 157 HOH HOH A . 
G 4 HOH 170 670 174 HOH HOH A . 
G 4 HOH 171 671 132 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   99.094 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9GA7 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     58.384 
_cell.length_a_esd                 ? 
_cell.length_b                     39.926 
_cell.length_b_esd                 ? 
_cell.length_c                     65.904 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        2 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9GA7 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9GA7 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.06 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          40.39 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              4.6 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M sodium acetate (pH 4.6), 0.2 M ammonium sulfate, and 25 % (v/v) PEG 4000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2002-07-21 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.99 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE ID30B' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.99 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ID30B 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9GA7 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.4 
_reflns.d_resolution_low                               65.1 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     51347 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           95.3 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          8.9 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.048 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.45 
_reflns_shell.d_res_low                                     1.47 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2372 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.495 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.001 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            0.001 
_refine.aniso_B[2][2]                            -0.000 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            0.001 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               20.000 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.964 
_refine.correlation_coeff_Fo_to_Fc_free          0.962 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9GA7 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.446 
_refine.ls_d_res_low                             65.076 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     51336 
_refine.ls_number_reflns_R_free                  2538 
_refine.ls_number_reflns_R_work                  48798 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    95.077 
_refine.ls_percent_reflns_R_free                 4.944 
_refine.ls_R_factor_all                          0.187 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2086 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1863 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.074 
_refine.pdbx_overall_ESU_R_Free                  0.073 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             1.602 
_refine.overall_SU_ML                            0.058 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        2479 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         21 
_refine_hist.number_atoms_solvent             171 
_refine_hist.number_atoms_total               2671 
_refine_hist.d_res_high                       1.446 
_refine_hist.d_res_low                        65.076 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  0.012  2524 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  2427 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.787  1.841  3387 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.613  1.793  5579 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 5.859  5.000  313  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 9.035  5.000  24   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 11.807 10.000 485  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 15.599 10.000 120  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.084  0.200  380  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.008  0.020  2985 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  589  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.250  0.200  543  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.182  0.200  2169 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.183  0.200  1280 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.074  0.200  1345 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.247  0.200  113  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.013  0.200  1    ? r_symmetry_xyhbond_nbd_other   ? ? 
'X-RAY DIFFRACTION' ? 0.144  0.200  4    ? r_metal_ion_refined            ? ? 
'X-RAY DIFFRACTION' ? 0.230  0.200  18   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.176  0.200  65   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.198  0.200  11   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.025  1.852  1255 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.005  1.850  1254 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 3.250  3.327  1567 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.251  3.327  1568 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 3.398  2.305  1269 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 3.363  2.269  1254 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 5.261  4.048  1820 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 5.219  3.980  1797 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 7.794  21.837 2934 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 7.734  21.375 2911 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.446 1.484  3989 . 187 3479 91.9027 . 0.333 . . 0.331 . . . . . 0.297 . 20 . 0.915 0.900 0.363 
'X-RAY DIFFRACTION' 1.484 1.524  3856 . 190 3590 98.0290 . 0.296 . . 0.296 . . . . . 0.254 . 20 . 0.934 0.933 0.298 
'X-RAY DIFFRACTION' 1.524 1.568  3759 . 181 3477 97.3131 . 0.280 . . 0.278 . . . . . 0.238 . 20 . 0.944 0.934 0.310 
'X-RAY DIFFRACTION' 1.568 1.617  3634 . 184 3350 97.2482 . 0.253 . . 0.251 . . . . . 0.210 . 20 . 0.956 0.950 0.296 
'X-RAY DIFFRACTION' 1.617 1.670  3571 . 172 3288 96.8916 . 0.240 . . 0.240 . . . . . 0.194 . 20 . 0.960 0.962 0.236 
'X-RAY DIFFRACTION' 1.670 1.728  3409 . 184 3120 96.9199 . 0.219 . . 0.217 . . . . . 0.183 . 20 . 0.969 0.956 0.265 
'X-RAY DIFFRACTION' 1.728 1.793  3303 . 146 3061 97.0936 . 0.204 . . 0.201 . . . . . 0.171 . 20 . 0.973 0.963 0.255 
'X-RAY DIFFRACTION' 1.793 1.866  3172 . 131 2930 96.5006 . 0.191 . . 0.190 . . . . . 0.167 . 20 . 0.977 0.969 0.208 
'X-RAY DIFFRACTION' 1.866 1.949  3060 . 152 2813 96.8954 . 0.184 . . 0.183 . . . . . 0.165 . 20 . 0.980 0.974 0.209 
'X-RAY DIFFRACTION' 1.949 2.044  2919 . 150 2652 95.9918 . 0.170 . . 0.167 . . . . . 0.153 . 20 . 0.984 0.970 0.220 
'X-RAY DIFFRACTION' 2.044 2.155  2805 . 130 2573 96.3636 . 0.169 . . 0.168 . . . . . 0.161 . 20 . 0.985 0.979 0.188 
'X-RAY DIFFRACTION' 2.155 2.285  2639 . 139 2387 95.7181 . 0.162 . . 0.161 . . . . . 0.156 . 20 . 0.986 0.981 0.175 
'X-RAY DIFFRACTION' 2.285 2.443  2476 . 106 2241 94.7900 . 0.157 . . 0.156 . . . . . 0.157 . 20 . 0.986 0.983 0.170 
'X-RAY DIFFRACTION' 2.443 2.639  2334 . 108 2069 93.2733 . 0.158 . . 0.156 . . . . . 0.162 . 20 . 0.986 0.977 0.190 
'X-RAY DIFFRACTION' 2.639 2.890  2126 . 84  1884 92.5682 . 0.175 . . 0.174 . . . . . 0.186 . 20 . 0.981 0.978 0.194 
'X-RAY DIFFRACTION' 2.890 3.230  1946 . 90  1696 91.7780 . 0.178 . . 0.176 . . . . . 0.193 . 20 . 0.981 0.976 0.214 
'X-RAY DIFFRACTION' 3.230 3.728  1720 . 70  1480 90.1163 . 0.170 . . 0.169 . . . . . 0.192 . 20 . 0.983 0.978 0.193 
'X-RAY DIFFRACTION' 3.728 4.563  1455 . 70  1220 88.6598 . 0.151 . . 0.151 . . . . . 0.181 . 20 . 0.987 0.988 0.150 
'X-RAY DIFFRACTION' 4.563 6.437  1161 . 42  955  85.8742 . 0.205 . . 0.205 . . . . . 0.251 . 20 . 0.985 0.983 0.221 
'X-RAY DIFFRACTION' 6.437 65.076 660  . 22  533  84.0909 . 0.221 . . 0.220 . . . . . 0.294 . 20 . 0.970 0.970 0.244 
# 
_struct.entry_id                     9GA7 
_struct.title                        
'The crystal structure of human Annexin A4 derived from crystal grown at 4 mM CaCl2 and retro-soaking' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9GA7 
_struct_keywords.text            
'Calcium/phospholipid-binding protein, complex with calcium (from retro-soaking), SIGNALING PROTEIN' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    ANXA4_HUMAN 
_struct_ref.pdbx_db_accession          P09525 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MATKGGTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSELSGNFEQVI
VGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGR
DEGNYLDDALVRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIV
KCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDD
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9GA7 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 319 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P09525 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  319 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       319 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9GA7 HIS A 320 ? UNP P09525 ? ? 'expression tag' 320 1 
1 9GA7 HIS A 321 ? UNP P09525 ? ? 'expression tag' 321 2 
1 9GA7 HIS A 322 ? UNP P09525 ? ? 'expression tag' 322 3 
1 9GA7 HIS A 323 ? UNP P09525 ? ? 'expression tag' 323 4 
1 9GA7 HIS A 324 ? UNP P09525 ? ? 'expression tag' 324 5 
1 9GA7 HIS A 325 ? UNP P09525 ? ? 'expression tag' 325 6 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 610   ? 
1 MORE         -43   ? 
1 'SSA (A^2)'  15250 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASN A 15  ? LYS A 28  ? ASN A 15  LYS A 28  1 ? 14 
HELX_P HELX_P2  AA2 ASP A 33  ? ALA A 42  ? ASP A 33  ALA A 42  1 ? 10 
HELX_P HELX_P3  AA3 ASN A 45  ? GLY A 61  ? ASN A 45  GLY A 61  1 ? 17 
HELX_P HELX_P4  AA4 ASP A 63  ? LEU A 72  ? ASP A 63  LEU A 72  1 ? 10 
HELX_P HELX_P5  AA5 SER A 73  ? THR A 85  ? SER A 73  THR A 85  1 ? 13 
HELX_P HELX_P6  AA6 PRO A 86  ? LYS A 100 ? PRO A 86  LYS A 100 1 ? 15 
HELX_P HELX_P7  AA7 ASP A 105 ? ARG A 116 ? ASP A 105 ARG A 116 1 ? 12 
HELX_P HELX_P8  AA8 THR A 117 ? GLY A 133 ? THR A 117 GLY A 133 1 ? 17 
HELX_P HELX_P9  AA9 SER A 135 ? THR A 144 ? SER A 135 THR A 144 1 ? 10 
HELX_P HELX_P10 AB1 SER A 145 ? GLY A 158 ? SER A 145 GLY A 158 1 ? 14 
HELX_P HELX_P11 AB2 ASP A 167 ? GLY A 182 ? ASP A 167 GLY A 182 1 ? 16 
HELX_P HELX_P12 AB3 ASP A 189 ? ARG A 200 ? ASP A 189 ARG A 200 1 ? 12 
HELX_P HELX_P13 AB4 ASN A 201 ? GLN A 217 ? ASN A 201 GLN A 217 1 ? 17 
HELX_P HELX_P14 AB5 ASP A 219 ? THR A 228 ? ASP A 219 THR A 228 1 ? 10 
HELX_P HELX_P15 AB6 SER A 229 ? LYS A 259 ? SER A 229 LYS A 259 1 ? 31 
HELX_P HELX_P16 AB7 ASP A 264 ? ALA A 276 ? ASP A 264 ALA A 276 1 ? 13 
HELX_P HELX_P17 AB8 ASP A 279 ? GLY A 292 ? ASP A 279 GLY A 292 1 ? 14 
HELX_P HELX_P18 AB9 SER A 294 ? THR A 303 ? SER A 294 THR A 303 1 ? 10 
HELX_P HELX_P19 AC1 SER A 304 ? GLY A 316 ? SER A 304 GLY A 316 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A MET 27 O   ? ? ? 1_555 B CA  . CA ? ? A MET 27  A CA  401 1_555 ? ? ? ? ? ? ? 2.260 ? ? 
metalc2 metalc ? ? A GLY 29 O   ? ? ? 1_555 B CA  . CA ? ? A GLY 29  A CA  401 1_555 ? ? ? ? ? ? ? 2.284 ? ? 
metalc3 metalc ? ? A GLY 31 O   ? ? ? 1_555 B CA  . CA ? ? A GLY 31  A CA  401 1_555 ? ? ? ? ? ? ? 2.391 ? ? 
metalc4 metalc ? ? A GLU 71 OE1 ? ? ? 1_555 B CA  . CA ? ? A GLU 71  A CA  401 1_555 ? ? ? ? ? ? ? 2.480 ? ? 
metalc5 metalc ? ? A GLU 71 OE2 ? ? ? 1_555 B CA  . CA ? ? A GLU 71  A CA  401 1_555 ? ? ? ? ? ? ? 2.787 ? ? 
metalc6 metalc ? ? B CA  .  CA  ? ? ? 1_555 G HOH . O  ? ? A CA  401 A HOH 502 1_555 ? ? ? ? ? ? ? 2.226 ? ? 
metalc7 metalc ? ? B CA  .  CA  ? ? ? 1_555 G HOH . O  ? ? A CA  401 A HOH 568 1_555 ? ? ? ? ? ? ? 2.585 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O   ? A MET 27 ? A MET 27  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? A GLY 29 ? A GLY 29  ? 1_555 88.4  ? 
2  O   ? A MET 27 ? A MET 27  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? A GLY 31 ? A GLY 31  ? 1_555 100.6 ? 
3  O   ? A GLY 29 ? A GLY 29  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? A GLY 31 ? A GLY 31  ? 1_555 85.2  ? 
4  O   ? A MET 27 ? A MET 27  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 OE1 ? A GLU 71 ? A GLU 71  ? 1_555 89.3  ? 
5  O   ? A GLY 29 ? A GLY 29  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 OE1 ? A GLU 71 ? A GLU 71  ? 1_555 168.4 ? 
6  O   ? A GLY 31 ? A GLY 31  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 OE1 ? A GLU 71 ? A GLU 71  ? 1_555 84.1  ? 
7  O   ? A MET 27 ? A MET 27  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 OE2 ? A GLU 71 ? A GLU 71  ? 1_555 81.4  ? 
8  O   ? A GLY 29 ? A GLY 29  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 OE2 ? A GLU 71 ? A GLU 71  ? 1_555 141.5 ? 
9  O   ? A GLY 31 ? A GLY 31  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 OE2 ? A GLU 71 ? A GLU 71  ? 1_555 133.1 ? 
10 OE1 ? A GLU 71 ? A GLU 71  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 OE2 ? A GLU 71 ? A GLU 71  ? 1_555 49.0  ? 
11 O   ? A MET 27 ? A MET 27  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 502 ? 1_555 87.8  ? 
12 O   ? A GLY 29 ? A GLY 29  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 502 ? 1_555 97.5  ? 
13 O   ? A GLY 31 ? A GLY 31  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 502 ? 1_555 171.3 ? 
14 OE1 ? A GLU 71 ? A GLU 71  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 502 ? 1_555 93.7  ? 
15 OE2 ? A GLU 71 ? A GLU 71  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 502 ? 1_555 45.4  ? 
16 O   ? A MET 27 ? A MET 27  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 568 ? 1_555 170.4 ? 
17 O   ? A GLY 29 ? A GLY 29  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 568 ? 1_555 90.2  ? 
18 O   ? A GLY 31 ? A GLY 31  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 568 ? 1_555 88.8  ? 
19 OE1 ? A GLU 71 ? A GLU 71  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 568 ? 1_555 93.9  ? 
20 OE2 ? A GLU 71 ? A GLU 71  ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 568 ? 1_555 94.0  ? 
21 O   ? G HOH .  ? A HOH 502 ? 1_555 CA ? B CA . ? A CA 401 ? 1_555 O   ? G HOH .  ? A HOH 568 ? 1_555 82.9  ? 
# 
_pdbx_entry_details.entry_id                   9GA7 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   A HOH 506 ? ? O A HOH 549 ? ? 1.42 
2 1 O   A HOH 501 ? ? O A HOH 611 ? ? 1.69 
3 1 OD1 A ASP 63  ? ? O A HOH 501 ? ? 1.93 
4 1 OE2 A GLU 71  ? ? O A HOH 502 ? ? 2.00 
5 1 O   A SER 12  ? ? O A HOH 503 ? ? 2.02 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 NE A ARG 96  ? ? CZ A ARG 96  ? ? NH1 A ARG 96  ? ? 123.60 120.30 3.30   0.50 N 
2 1 NE A ARG 96  ? ? CZ A ARG 96  ? ? NH2 A ARG 96  ? ? 117.03 120.30 -3.27  0.50 N 
3 1 NE A ARG 97  ? ? CZ A ARG 97  ? ? NH2 A ARG 97  ? ? 117.14 120.30 -3.16  0.50 N 
4 1 CG A GLU 277 ? ? CD A GLU 277 ? ? OE2 A GLU 277 ? ? 105.44 118.30 -12.86 2.00 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PHE A 146 ? ? 63.68   -143.14 
2 1 ASN A 164 ? ? -142.01 21.72   
3 1 TRP A 186 ? ? -166.25 -6.88   
4 1 THR A 188 ? ? -24.11  158.01  
5 1 ASN A 245 ? ? -166.05 104.37  
6 1 ILE A 278 ? ? -103.11 -62.04  
7 1 ASP A 279 ? ? -149.51 23.75   
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 123 ? ? 0.089 'SIDE CHAIN' 
2 1 ARG A 172 ? ? 0.081 'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ALA 2   ? A ALA 2   
3  1 Y 1 A GLY 317 ? A GLY 317 
4  1 Y 1 A ASP 318 ? A ASP 318 
5  1 Y 1 A ASP 319 ? A ASP 319 
6  1 Y 1 A HIS 320 ? A HIS 320 
7  1 Y 1 A HIS 321 ? A HIS 321 
8  1 Y 1 A HIS 322 ? A HIS 322 
9  1 Y 1 A HIS 323 ? A HIS 323 
10 1 Y 1 A HIS 324 ? A HIS 324 
11 1 Y 1 A HIS 325 ? A HIS 325 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CA  CA   CA N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
HOH O    O  N N 159 
HOH H1   H  N N 160 
HOH H2   H  N N 161 
ILE N    N  N N 162 
ILE CA   C  N S 163 
ILE C    C  N N 164 
ILE O    O  N N 165 
ILE CB   C  N S 166 
ILE CG1  C  N N 167 
ILE CG2  C  N N 168 
ILE CD1  C  N N 169 
ILE OXT  O  N N 170 
ILE H    H  N N 171 
ILE H2   H  N N 172 
ILE HA   H  N N 173 
ILE HB   H  N N 174 
ILE HG12 H  N N 175 
ILE HG13 H  N N 176 
ILE HG21 H  N N 177 
ILE HG22 H  N N 178 
ILE HG23 H  N N 179 
ILE HD11 H  N N 180 
ILE HD12 H  N N 181 
ILE HD13 H  N N 182 
ILE HXT  H  N N 183 
LEU N    N  N N 184 
LEU CA   C  N S 185 
LEU C    C  N N 186 
LEU O    O  N N 187 
LEU CB   C  N N 188 
LEU CG   C  N N 189 
LEU CD1  C  N N 190 
LEU CD2  C  N N 191 
LEU OXT  O  N N 192 
LEU H    H  N N 193 
LEU H2   H  N N 194 
LEU HA   H  N N 195 
LEU HB2  H  N N 196 
LEU HB3  H  N N 197 
LEU HG   H  N N 198 
LEU HD11 H  N N 199 
LEU HD12 H  N N 200 
LEU HD13 H  N N 201 
LEU HD21 H  N N 202 
LEU HD22 H  N N 203 
LEU HD23 H  N N 204 
LEU HXT  H  N N 205 
LYS N    N  N N 206 
LYS CA   C  N S 207 
LYS C    C  N N 208 
LYS O    O  N N 209 
LYS CB   C  N N 210 
LYS CG   C  N N 211 
LYS CD   C  N N 212 
LYS CE   C  N N 213 
LYS NZ   N  N N 214 
LYS OXT  O  N N 215 
LYS H    H  N N 216 
LYS H2   H  N N 217 
LYS HA   H  N N 218 
LYS HB2  H  N N 219 
LYS HB3  H  N N 220 
LYS HG2  H  N N 221 
LYS HG3  H  N N 222 
LYS HD2  H  N N 223 
LYS HD3  H  N N 224 
LYS HE2  H  N N 225 
LYS HE3  H  N N 226 
LYS HZ1  H  N N 227 
LYS HZ2  H  N N 228 
LYS HZ3  H  N N 229 
LYS HXT  H  N N 230 
MET N    N  N N 231 
MET CA   C  N S 232 
MET C    C  N N 233 
MET O    O  N N 234 
MET CB   C  N N 235 
MET CG   C  N N 236 
MET SD   S  N N 237 
MET CE   C  N N 238 
MET OXT  O  N N 239 
MET H    H  N N 240 
MET H2   H  N N 241 
MET HA   H  N N 242 
MET HB2  H  N N 243 
MET HB3  H  N N 244 
MET HG2  H  N N 245 
MET HG3  H  N N 246 
MET HE1  H  N N 247 
MET HE2  H  N N 248 
MET HE3  H  N N 249 
MET HXT  H  N N 250 
PHE N    N  N N 251 
PHE CA   C  N S 252 
PHE C    C  N N 253 
PHE O    O  N N 254 
PHE CB   C  N N 255 
PHE CG   C  Y N 256 
PHE CD1  C  Y N 257 
PHE CD2  C  Y N 258 
PHE CE1  C  Y N 259 
PHE CE2  C  Y N 260 
PHE CZ   C  Y N 261 
PHE OXT  O  N N 262 
PHE H    H  N N 263 
PHE H2   H  N N 264 
PHE HA   H  N N 265 
PHE HB2  H  N N 266 
PHE HB3  H  N N 267 
PHE HD1  H  N N 268 
PHE HD2  H  N N 269 
PHE HE1  H  N N 270 
PHE HE2  H  N N 271 
PHE HZ   H  N N 272 
PHE HXT  H  N N 273 
PRO N    N  N N 274 
PRO CA   C  N S 275 
PRO C    C  N N 276 
PRO O    O  N N 277 
PRO CB   C  N N 278 
PRO CG   C  N N 279 
PRO CD   C  N N 280 
PRO OXT  O  N N 281 
PRO H    H  N N 282 
PRO HA   H  N N 283 
PRO HB2  H  N N 284 
PRO HB3  H  N N 285 
PRO HG2  H  N N 286 
PRO HG3  H  N N 287 
PRO HD2  H  N N 288 
PRO HD3  H  N N 289 
PRO HXT  H  N N 290 
SER N    N  N N 291 
SER CA   C  N S 292 
SER C    C  N N 293 
SER O    O  N N 294 
SER CB   C  N N 295 
SER OG   O  N N 296 
SER OXT  O  N N 297 
SER H    H  N N 298 
SER H2   H  N N 299 
SER HA   H  N N 300 
SER HB2  H  N N 301 
SER HB3  H  N N 302 
SER HG   H  N N 303 
SER HXT  H  N N 304 
SO4 S    S  N N 305 
SO4 O1   O  N N 306 
SO4 O2   O  N N 307 
SO4 O3   O  N N 308 
SO4 O4   O  N N 309 
THR N    N  N N 310 
THR CA   C  N S 311 
THR C    C  N N 312 
THR O    O  N N 313 
THR CB   C  N R 314 
THR OG1  O  N N 315 
THR CG2  C  N N 316 
THR OXT  O  N N 317 
THR H    H  N N 318 
THR H2   H  N N 319 
THR HA   H  N N 320 
THR HB   H  N N 321 
THR HG1  H  N N 322 
THR HG21 H  N N 323 
THR HG22 H  N N 324 
THR HG23 H  N N 325 
THR HXT  H  N N 326 
TRP N    N  N N 327 
TRP CA   C  N S 328 
TRP C    C  N N 329 
TRP O    O  N N 330 
TRP CB   C  N N 331 
TRP CG   C  Y N 332 
TRP CD1  C  Y N 333 
TRP CD2  C  Y N 334 
TRP NE1  N  Y N 335 
TRP CE2  C  Y N 336 
TRP CE3  C  Y N 337 
TRP CZ2  C  Y N 338 
TRP CZ3  C  Y N 339 
TRP CH2  C  Y N 340 
TRP OXT  O  N N 341 
TRP H    H  N N 342 
TRP H2   H  N N 343 
TRP HA   H  N N 344 
TRP HB2  H  N N 345 
TRP HB3  H  N N 346 
TRP HD1  H  N N 347 
TRP HE1  H  N N 348 
TRP HE3  H  N N 349 
TRP HZ2  H  N N 350 
TRP HZ3  H  N N 351 
TRP HH2  H  N N 352 
TRP HXT  H  N N 353 
TYR N    N  N N 354 
TYR CA   C  N S 355 
TYR C    C  N N 356 
TYR O    O  N N 357 
TYR CB   C  N N 358 
TYR CG   C  Y N 359 
TYR CD1  C  Y N 360 
TYR CD2  C  Y N 361 
TYR CE1  C  Y N 362 
TYR CE2  C  Y N 363 
TYR CZ   C  Y N 364 
TYR OH   O  N N 365 
TYR OXT  O  N N 366 
TYR H    H  N N 367 
TYR H2   H  N N 368 
TYR HA   H  N N 369 
TYR HB2  H  N N 370 
TYR HB3  H  N N 371 
TYR HD1  H  N N 372 
TYR HD2  H  N N 373 
TYR HE1  H  N N 374 
TYR HE2  H  N N 375 
TYR HH   H  N N 376 
TYR HXT  H  N N 377 
VAL N    N  N N 378 
VAL CA   C  N S 379 
VAL C    C  N N 380 
VAL O    O  N N 381 
VAL CB   C  N N 382 
VAL CG1  C  N N 383 
VAL CG2  C  N N 384 
VAL OXT  O  N N 385 
VAL H    H  N N 386 
VAL H2   H  N N 387 
VAL HA   H  N N 388 
VAL HB   H  N N 389 
VAL HG11 H  N N 390 
VAL HG12 H  N N 391 
VAL HG13 H  N N 392 
VAL HG21 H  N N 393 
VAL HG22 H  N N 394 
VAL HG23 H  N N 395 
VAL HXT  H  N N 396 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
SO4 S   O1   doub N N 290 
SO4 S   O2   doub N N 291 
SO4 S   O3   sing N N 292 
SO4 S   O4   sing N N 293 
THR N   CA   sing N N 294 
THR N   H    sing N N 295 
THR N   H2   sing N N 296 
THR CA  C    sing N N 297 
THR CA  CB   sing N N 298 
THR CA  HA   sing N N 299 
THR C   O    doub N N 300 
THR C   OXT  sing N N 301 
THR CB  OG1  sing N N 302 
THR CB  CG2  sing N N 303 
THR CB  HB   sing N N 304 
THR OG1 HG1  sing N N 305 
THR CG2 HG21 sing N N 306 
THR CG2 HG22 sing N N 307 
THR CG2 HG23 sing N N 308 
THR OXT HXT  sing N N 309 
TRP N   CA   sing N N 310 
TRP N   H    sing N N 311 
TRP N   H2   sing N N 312 
TRP CA  C    sing N N 313 
TRP CA  CB   sing N N 314 
TRP CA  HA   sing N N 315 
TRP C   O    doub N N 316 
TRP C   OXT  sing N N 317 
TRP CB  CG   sing N N 318 
TRP CB  HB2  sing N N 319 
TRP CB  HB3  sing N N 320 
TRP CG  CD1  doub Y N 321 
TRP CG  CD2  sing Y N 322 
TRP CD1 NE1  sing Y N 323 
TRP CD1 HD1  sing N N 324 
TRP CD2 CE2  doub Y N 325 
TRP CD2 CE3  sing Y N 326 
TRP NE1 CE2  sing Y N 327 
TRP NE1 HE1  sing N N 328 
TRP CE2 CZ2  sing Y N 329 
TRP CE3 CZ3  doub Y N 330 
TRP CE3 HE3  sing N N 331 
TRP CZ2 CH2  doub Y N 332 
TRP CZ2 HZ2  sing N N 333 
TRP CZ3 CH2  sing Y N 334 
TRP CZ3 HZ3  sing N N 335 
TRP CH2 HH2  sing N N 336 
TRP OXT HXT  sing N N 337 
TYR N   CA   sing N N 338 
TYR N   H    sing N N 339 
TYR N   H2   sing N N 340 
TYR CA  C    sing N N 341 
TYR CA  CB   sing N N 342 
TYR CA  HA   sing N N 343 
TYR C   O    doub N N 344 
TYR C   OXT  sing N N 345 
TYR CB  CG   sing N N 346 
TYR CB  HB2  sing N N 347 
TYR CB  HB3  sing N N 348 
TYR CG  CD1  doub Y N 349 
TYR CG  CD2  sing Y N 350 
TYR CD1 CE1  sing Y N 351 
TYR CD1 HD1  sing N N 352 
TYR CD2 CE2  doub Y N 353 
TYR CD2 HD2  sing N N 354 
TYR CE1 CZ   doub Y N 355 
TYR CE1 HE1  sing N N 356 
TYR CE2 CZ   sing Y N 357 
TYR CE2 HE2  sing N N 358 
TYR CZ  OH   sing N N 359 
TYR OH  HH   sing N N 360 
TYR OXT HXT  sing N N 361 
VAL N   CA   sing N N 362 
VAL N   H    sing N N 363 
VAL N   H2   sing N N 364 
VAL CA  C    sing N N 365 
VAL CA  CB   sing N N 366 
VAL CA  HA   sing N N 367 
VAL C   O    doub N N 368 
VAL C   OXT  sing N N 369 
VAL CB  CG1  sing N N 370 
VAL CB  CG2  sing N N 371 
VAL CB  HB   sing N N 372 
VAL CG1 HG11 sing N N 373 
VAL CG1 HG12 sing N N 374 
VAL CG1 HG13 sing N N 375 
VAL CG2 HG21 sing N N 376 
VAL CG2 HG22 sing N N 377 
VAL CG2 HG23 sing N N 378 
VAL OXT HXT  sing N N 379 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   2ZOC 
_pdbx_initial_refinement_model.details          ? 
# 
_pdbx_related_exp_data_set.ordinal              1 
_pdbx_related_exp_data_set.data_reference       10.15151/ESRF-ES-771453717 
_pdbx_related_exp_data_set.metadata_reference   ? 
_pdbx_related_exp_data_set.data_set_type        'diffraction image data' 
_pdbx_related_exp_data_set.details              ? 
# 
_atom_sites.entry_id                    9GA7 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.017128 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.002742 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.025046 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.015367 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512  0.2156   
CA 20 20 8.6266  10.4421 7.3873 0.6599  1.5899 85.7484 1.0211 178.4370 1.6728   
H  1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997  0.0030   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826   -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089  0.2508   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720  1.0532   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N  N   . THR A 1 3   ? 36.122 26.305  43.612 1.000 45.085  0 3   THR A N   1 ? 
ATOM   2    C  CA  . THR A 1 3   ? 36.741 27.582  43.173 1.000 46.111  0 3   THR A CA  1 ? 
ATOM   3    C  C   . THR A 1 3   ? 37.347 27.417  41.777 1.000 42.909  0 3   THR A C   1 ? 
ATOM   4    O  O   . THR A 1 3   ? 36.976 28.169  40.887 1.000 46.274  0 3   THR A O   1 ? 
ATOM   5    C  CB  . THR A 1 3   ? 37.732 28.168  44.195 1.000 52.122  0 3   THR A CB  1 ? 
ATOM   6    O  OG1 . THR A 1 3   ? 39.000 28.357  43.563 1.000 54.551  0 3   THR A OG1 1 ? 
ATOM   7    C  CG2 . THR A 1 3   ? 37.965 27.303  45.426 1.000 55.064  0 3   THR A CG2 1 ? 
ATOM   8    N  N   . LYS A 1 4   ? 38.248 26.441  41.573 1.000 34.318  0 4   LYS A N   1 ? 
ATOM   9    C  CA  . LYS A 1 4   ? 38.922 26.257  40.290 1.000 30.932  0 4   LYS A CA  1 ? 
ATOM   10   C  C   . LYS A 1 4   ? 38.330 25.099  39.477 1.000 26.786  0 4   LYS A C   1 ? 
ATOM   11   O  O   . LYS A 1 4   ? 38.353 25.134  38.243 1.000 28.774  0 4   LYS A O   1 ? 
ATOM   12   C  CB  . LYS A 1 4   ? 40.438 26.129  40.477 1.000 34.986  0 4   LYS A CB  1 ? 
ATOM   13   C  CG  . LYS A 1 4   ? 41.047 27.250  41.307 1.000 40.438  0 4   LYS A CG  1 ? 
ATOM   14   C  CD  . LYS A 1 4   ? 42.562 27.313  41.249 1.000 49.109  0 4   LYS A CD  1 ? 
ATOM   15   C  CE  . LYS A 1 4   ? 43.191 26.047  41.709 1.000 51.094  0 4   LYS A CE  1 ? 
ATOM   16   N  NZ  . LYS A 1 4   ? 44.649 26.177  41.706 1.000 57.835  0 4   LYS A NZ  1 ? 
ATOM   17   N  N   . GLY A 1 5   ? 37.808 24.058  40.125 1.000 22.418  0 5   GLY A N   1 ? 
ATOM   18   C  CA  . GLY A 1 5   ? 37.040 23.070  39.385 1.000 20.745  0 5   GLY A CA  1 ? 
ATOM   19   C  C   . GLY A 1 5   ? 37.907 21.914  38.873 1.000 19.648  0 5   GLY A C   1 ? 
ATOM   20   O  O   . GLY A 1 5   ? 38.973 21.652  39.451 1.000 19.058  0 5   GLY A O   1 ? 
ATOM   21   N  N   . GLY A 1 6   ? 37.424 21.218  37.827 1.000 18.004  0 6   GLY A N   1 ? 
ATOM   22   C  CA  . GLY A 1 6   ? 38.007 19.950  37.390 1.000 20.337  0 6   GLY A CA  1 ? 
ATOM   23   C  C   . GLY A 1 6   ? 39.126 20.119  36.368 1.000 18.701  0 6   GLY A C   1 ? 
ATOM   24   O  O   . GLY A 1 6   ? 39.263 21.189  35.785 1.000 19.975  0 6   GLY A O   1 ? 
ATOM   25   N  N   . THR A 1 7   ? 39.936 19.072  36.171 1.000 17.833  0 7   THR A N   1 ? 
ATOM   26   C  CA  . THR A 1 7   ? 40.927 19.023  35.113 1.000 18.936  0 7   THR A CA  1 ? 
ATOM   27   C  C   . THR A 1 7   ? 40.332 18.486  33.819 1.000 21.071  0 7   THR A C   1 ? 
ATOM   28   O  O   . THR A 1 7   ? 40.734 18.914  32.745 1.000 23.276  0 7   THR A O   1 ? 
ATOM   29   C  CB  . THR A 1 7   ? 42.115 18.169  35.528 1.000 20.127  0 7   THR A CB  1 ? 
ATOM   30   O  OG1 . THR A 1 7   ? 41.516 16.976  36.030 1.000 20.982  0 7   THR A OG1 1 ? 
ATOM   31   C  CG2 . THR A 1 7   ? 42.922 18.858  36.599 1.000 19.936  0 7   THR A CG2 1 ? 
ATOM   32   N  N   . VAL A 1 8   ? 39.368 17.569  33.926 1.000 20.650  0 8   VAL A N   1 ? 
ATOM   33   C  CA  . VAL A 1 8   ? 38.754 16.940  32.771 1.000 20.273  0 8   VAL A CA  1 ? 
ATOM   34   C  C   . VAL A 1 8   ? 37.467 17.677  32.467 1.000 22.360  0 8   VAL A C   1 ? 
ATOM   35   O  O   . VAL A 1 8   ? 36.597 17.803  33.329 1.000 23.914  0 8   VAL A O   1 ? 
ATOM   36   C  CB  . VAL A 1 8   ? 38.492 15.453  33.051 1.000 21.579  0 8   VAL A CB  1 ? 
ATOM   37   C  CG1 . VAL A 1 8   ? 37.667 14.816  31.952 1.000 20.770  0 8   VAL A CG1 1 ? 
ATOM   38   C  CG2 . VAL A 1 8   ? 39.795 14.710  33.229 1.000 21.826  0 8   VAL A CG2 1 ? 
ATOM   39   N  N   . LYS A 1 9   ? 37.361 18.143  31.221 1.000 22.931  0 9   LYS A N   1 ? 
ATOM   40   C  CA  . LYS A 1 9   ? 36.197 18.891  30.788 1.000 27.377  0 9   LYS A CA  1 ? 
ATOM   41   C  C   . LYS A 1 9   ? 35.634 18.212  29.543 1.000 24.376  0 9   LYS A C   1 ? 
ATOM   42   O  O   . LYS A 1 9   ? 36.329 17.411  28.917 1.000 20.872  0 9   LYS A O   1 ? 
ATOM   43   C  CB  . LYS A 1 9   ? 36.583 20.352  30.517 1.000 31.943  0 9   LYS A CB  1 ? 
ATOM   44   C  CG  . LYS A 1 9   ? 37.138 21.086  31.752 1.000 36.149  0 9   LYS A CG  1 ? 
ATOM   45   C  CD  . LYS A 1 9   ? 36.672 22.531  31.866 1.000 43.243  0 9   LYS A CD  1 ? 
ATOM   46   C  CE  . LYS A 1 9   ? 37.142 23.228  33.096 1.000 44.796  0 9   LYS A CE  1 ? 
ATOM   47   N  NZ  . LYS A 1 9   ? 36.422 22.798  34.294 1.000 46.751  0 9   LYS A NZ  1 ? 
ATOM   48   N  N   . ALA A 1 10  ? 34.381 18.546  29.201 1.000 23.985  0 10  ALA A N   1 ? 
ATOM   49   C  CA  . ALA A 1 10  ? 33.811 18.090  27.944 1.000 21.538  0 10  ALA A CA  1 ? 
ATOM   50   C  C   . ALA A 1 10  ? 34.694 18.585  26.803 1.000 21.890  0 10  ALA A C   1 ? 
ATOM   51   O  O   . ALA A 1 10  ? 35.121 19.756  26.775 1.000 22.247  0 10  ALA A O   1 ? 
ATOM   52   C  CB  . ALA A 1 10  ? 32.403 18.578  27.789 1.000 24.680  0 10  ALA A CB  1 ? 
ATOM   53   N  N   . ALA A 1 11  ? 34.940 17.693  25.845 1.000 18.067  0 11  ALA A N   1 ? 
ATOM   54   C  CA  . ALA A 1 11  ? 35.633 18.056  24.626 1.000 18.792  0 11  ALA A CA  1 ? 
ATOM   55   C  C   . ALA A 1 11  ? 34.710 18.845  23.711 1.000 20.430  0 11  ALA A C   1 ? 
ATOM   56   O  O   . ALA A 1 11  ? 33.530 18.514  23.584 1.000 19.949  0 11  ALA A O   1 ? 
ATOM   57   C  CB  . ALA A 1 11  ? 36.168 16.843  23.922 1.000 17.921  0 11  ALA A CB  1 ? 
ATOM   58   N  N   . SER A 1 12  ? 35.311 19.826  23.019 1.000 25.193  0 12  SER A N   1 ? 
ATOM   59   C  CA  . SER A 1 12  ? 34.520 20.760  22.231 1.000 28.621  0 12  SER A CA  1 ? 
ATOM   60   C  C   . SER A 1 12  ? 34.112 20.212  20.856 1.000 32.519  0 12  SER A C   1 ? 
ATOM   61   O  O   . SER A 1 12  ? 32.981 20.478  20.419 1.000 38.662  0 12  SER A O   1 ? 
ATOM   62   C  CB  . SER A 1 12  ? 35.234 22.101  22.115 1.000 30.505  0 12  SER A CB  1 ? 
ATOM   63   O  OG  . SER A 1 12  ? 36.410 21.963  21.336 1.000 37.364  0 12  SER A OG  1 ? 
ATOM   64   N  N   . GLY A 1 13  ? 35.023 19.517  20.149 1.000 24.547  0 13  GLY A N   1 ? 
ATOM   65   C  CA  . GLY A 1 13  ? 34.796 19.024  18.792 1.000 23.677  0 13  GLY A CA  1 ? 
ATOM   66   C  C   . GLY A 1 13  ? 34.477 17.517  18.782 1.000 22.171  0 13  GLY A C   1 ? 
ATOM   67   O  O   . GLY A 1 13  ? 34.865 16.772  17.889 1.000 24.335  0 13  GLY A O   1 ? 
ATOM   68   N  N   . PHE A 1 14  ? 33.786 17.082  19.821 1.000 18.996  0 14  PHE A N   1 ? 
ATOM   69   C  CA  . PHE A 1 14  ? 33.559 15.661  20.107 1.000 17.519  0 14  PHE A CA  1 ? 
ATOM   70   C  C   . PHE A 1 14  ? 32.795 14.981  18.986 1.000 16.860  0 14  PHE A C   1 ? 
ATOM   71   O  O   . PHE A 1 14  ? 31.652 15.375  18.721 1.000 17.188  0 14  PHE A O   1 ? 
ATOM   72   C  CB  . PHE A 1 14  ? 32.763 15.634  21.410 1.000 16.716  0 14  PHE A CB  1 ? 
ATOM   73   C  CG  . PHE A 1 14  ? 32.249 14.275  21.837 1.000 15.491  0 14  PHE A CG  1 ? 
ATOM   74   C  CD1 . PHE A 1 14  ? 33.034 13.141  21.647 1.000 15.013  0 14  PHE A CD1 1 ? 
ATOM   75   C  CD2 . PHE A 1 14  ? 31.018 14.114  22.460 1.000 15.868  0 14  PHE A CD2 1 ? 
ATOM   76   C  CE1 . PHE A 1 14  ? 32.574 11.901  22.015 1.000 14.709  0 14  PHE A CE1 1 ? 
ATOM   77   C  CE2 . PHE A 1 14  ? 30.575 12.868  22.860 1.000 15.006  0 14  PHE A CE2 1 ? 
ATOM   78   C  CZ  . PHE A 1 14  ? 31.355 11.751  22.642 1.000 15.029  0 14  PHE A CZ  1 ? 
ATOM   79   N  N   . ASN A 1 15  ? 33.376 13.905  18.410 1.000 15.968  0 15  ASN A N   1 ? 
ATOM   80   C  CA  . ASN A 1 15  ? 32.689 13.059  17.448 1.000 16.530  0 15  ASN A CA  1 ? 
ATOM   81   C  C   . ASN A 1 15  ? 32.717 11.615  17.958 1.000 15.776  0 15  ASN A C   1 ? 
ATOM   82   O  O   . ASN A 1 15  ? 33.774 10.999  17.907 1.000 15.785  0 15  ASN A O   1 ? 
ATOM   83   C  CB  . ASN A 1 15  ? 33.273 13.208  16.052 1.000 19.775  0 15  ASN A CB  1 ? 
ATOM   84   C  CG  . ASN A 1 15  ? 32.390 12.546  15.035 1.000 22.669  0 15  ASN A CG  1 ? 
ATOM   85   O  OD1 . ASN A 1 15  ? 32.170 11.328  15.053 1.000 22.039  0 15  ASN A OD1 1 ? 
ATOM   86   N  ND2 . ASN A 1 15  ? 31.762 13.354  14.189 1.000 29.800  0 15  ASN A ND2 1 ? 
ATOM   87   N  N   . ALA A 1 16  ? 31.572 11.112  18.423 1.000 15.636  0 16  ALA A N   1 ? 
ATOM   88   C  CA  . ALA A 1 16  ? 31.507 9.829   19.101 1.000 13.651  0 16  ALA A CA  1 ? 
ATOM   89   C  C   . ALA A 1 16  ? 31.842 8.684   18.131 1.000 15.011  0 16  ALA A C   1 ? 
ATOM   90   O  O   . ALA A 1 16  ? 32.504 7.708   18.505 1.000 13.589  0 16  ALA A O   1 ? 
ATOM   91   C  CB  . ALA A 1 16  ? 30.193 9.674   19.781 1.000 14.055  0 16  ALA A CB  1 ? 
ATOM   92   N  N   . MET A 1 17  ? 31.432 8.808   16.873 1.000 15.522  0 17  MET A N   1 ? 
ATOM   93   C  CA  . MET A 1 17  ? 31.684 7.792   15.862 1.000 16.779  0 17  MET A CA  1 ? 
ATOM   94   C  C   . MET A 1 17  ? 33.170 7.715   15.535 1.000 17.046  0 17  MET A C   1 ? 
ATOM   95   O  O   . MET A 1 17  ? 33.726 6.622   15.396 1.000 16.357  0 17  MET A O   1 ? 
ATOM   96   C  CB  . MET A 1 17  ? 30.859 8.137   14.612 1.000 19.786  0 17  MET A CB  1 ? 
ATOM   97   C  CG  . MET A 1 17  ? 30.933 7.207   13.449 1.000 24.482  0 17  MET A CG  1 ? 
ATOM   98   S  SD  . MET A 1 17  ? 29.555 7.574   12.323 1.000 32.109  0 17  MET A SD  1 ? 
ATOM   99   C  CE  . MET A 1 17  ? 28.241 7.715   13.524 1.000 16.323  0 17  MET A CE  1 ? 
ATOM   100  N  N   . GLU A 1 18  ? 33.814 8.876   15.376 1.000 16.157  0 18  GLU A N   1 ? 
ATOM   101  C  CA  . GLU A 1 18  ? 35.228 8.969   15.109 1.000 17.322  0 18  GLU A CA  1 ? 
ATOM   102  C  C   . GLU A 1 18  ? 36.018 8.380   16.285 1.000 15.598  0 18  GLU A C   1 ? 
ATOM   103  O  O   . GLU A 1 18  ? 36.976 7.640   16.063 1.000 16.860  0 18  GLU A O   1 ? 
ATOM   104  C  CB  . GLU A 1 18  ? 35.582 10.446  14.878 1.000 22.824  0 18  GLU A CB  1 ? 
ATOM   105  C  CG  . GLU A 1 18  ? 37.037 10.718  14.515 1.000 31.579  0 18  GLU A CG  1 ? 
ATOM   106  C  CD  . GLU A 1 18  ? 37.365 12.216  14.402 1.000 44.741  0 18  GLU A CD  1 ? 
ATOM   107  O  OE1 . GLU A 1 18  ? 37.012 13.010  15.321 1.000 48.725  0 18  GLU A OE1 1 ? 
ATOM   108  O  OE2 . GLU A 1 18  ? 38.027 12.589  13.396 1.000 57.311  0 18  GLU A OE2 1 ? 
ATOM   109  N  N   . ASP A 1 19  ? 35.612 8.713   17.516 1.000 15.135  0 19  ASP A N   1 ? 
ATOM   110  C  CA  . ASP A 1 19  ? 36.240 8.177   18.712 1.000 13.555  0 19  ASP A CA  1 ? 
ATOM   111  C  C   . ASP A 1 19  ? 36.108 6.661   18.743 1.000 13.682  0 19  ASP A C   1 ? 
ATOM   112  O  O   . ASP A 1 19  ? 37.082 5.972   19.072 1.000 12.722  0 19  ASP A O   1 ? 
ATOM   113  C  CB  . ASP A 1 19  ? 35.700 8.775   20.000 1.000 12.300  0 19  ASP A CB  1 ? 
ATOM   114  C  CG  . ASP A 1 19  ? 36.066 10.237  20.251 1.000 15.868  0 19  ASP A CG  1 ? 
ATOM   115  O  OD1 . ASP A 1 19  ? 36.988 10.773  19.547 1.000 15.509  0 19  ASP A OD1 1 ? 
ATOM   116  O  OD2 . ASP A 1 19  ? 35.446 10.832  21.165 1.000 16.647  0 19  ASP A OD2 1 ? 
ATOM   117  N  N   . ALA A 1 20  ? 34.917 6.147   18.417 1.000 12.489  0 20  ALA A N   1 ? 
ATOM   118  C  CA  . ALA A 1 20  ? 34.740 4.695   18.374 1.000 14.141  0 20  ALA A CA  1 ? 
ATOM   119  C  C   . ALA A 1 20  ? 35.726 4.068   17.383 1.000 14.583  0 20  ALA A C   1 ? 
ATOM   120  O  O   . ALA A 1 20  ? 36.309 3.006   17.662 1.000 14.530  0 20  ALA A O   1 ? 
ATOM   121  C  CB  . ALA A 1 20  ? 33.325 4.341   18.014 1.000 15.576  0 20  ALA A CB  1 ? 
ATOM   122  N  N   . GLN A 1 21  ? 35.907 4.693   16.204 1.000 15.113  0 21  GLN A N   1 ? 
ATOM   123  C  CA  . GLN A 1 21  ? 36.808 4.188   15.176 1.000 17.294  0 21  GLN A CA  1 ? 
ATOM   124  C  C   . GLN A 1 21  ? 38.246 4.193   15.682 1.000 15.812  0 21  GLN A C   1 ? 
ATOM   125  O  O   . GLN A 1 21  ? 39.000 3.240   15.455 1.000 16.303  0 21  GLN A O   1 ? 
ATOM   126  C  CB  . GLN A 1 21  ? 36.687 4.912   13.829 1.000 19.463  0 21  GLN A CB  1 ? 
ATOM   127  C  CG  . GLN A 1 21  ? 35.324 4.702   13.170 1.000 23.232  0 21  GLN A CG  1 ? 
ATOM   128  C  CD  . GLN A 1 21  ? 35.036 5.653   12.033 1.000 33.474  0 21  GLN A CD  1 ? 
ATOM   129  O  OE1 . GLN A 1 21  ? 35.444 6.824   12.049 1.000 36.347  0 21  GLN A OE1 1 ? 
ATOM   130  N  NE2 . GLN A 1 21  ? 34.358 5.139   11.017 1.000 38.267  0 21  GLN A NE2 1 ? 
ATOM   131  N  N   . THR A 1 22  ? 38.612 5.266   16.377 1.000 15.717  0 22  THR A N   1 ? 
ATOM   132  C  CA  . THR A 1 22  ? 39.961 5.419   16.894 1.000 15.190  0 22  THR A CA  1 ? 
ATOM   133  C  C   . THR A 1 22  ? 40.230 4.294   17.890 1.000 14.892  0 22  THR A C   1 ? 
ATOM   134  O  O   . THR A 1 22  ? 41.309 3.703   17.936 1.000 15.148  0 22  THR A O   1 ? 
ATOM   135  C  CB  . THR A 1 22  ? 40.087 6.794   17.556 1.000 15.184  0 22  THR A CB  1 ? 
ATOM   136  O  OG1 . THR A 1 22  ? 39.940 7.784   16.527 1.000 17.720  0 22  THR A OG1 1 ? 
ATOM   137  C  CG2 . THR A 1 22  ? 41.438 7.023   18.203 1.000 16.406  0 22  THR A CG2 1 ? 
ATOM   138  N  N   . LEU A 1 23  ? 39.262 4.044   18.770 1.000 13.421  0 23  LEU A N   1 ? 
ATOM   139  C  CA  . LEU A 1 23  ? 39.419 3.028   19.803 1.000 12.288  0 23  LEU A CA  1 ? 
ATOM   140  C  C   . LEU A 1 23  ? 39.503 1.638   19.188 1.000 14.233  0 23  LEU A C   1 ? 
ATOM   141  O  O   . LEU A 1 23  ? 40.317 0.822   19.629 1.000 14.102  0 23  LEU A O   1 ? 
ATOM   142  C  CB  . LEU A 1 23  ? 38.309 3.124   20.856 1.000 12.533  0 23  LEU A CB  1 ? 
ATOM   143  C  CG  . LEU A 1 23  ? 38.350 4.415   21.705 1.000 12.467  0 23  LEU A CG  1 ? 
ATOM   144  C  CD1 . LEU A 1 23  ? 37.010 4.658   22.400 1.000 12.896  0 23  LEU A CD1 1 ? 
ATOM   145  C  CD2 . LEU A 1 23  ? 39.495 4.327   22.705 1.000 13.264  0 23  LEU A CD2 1 ? 
ATOM   146  N  N   . ARG A 1 24  ? 38.675 1.344   18.184 1.000 14.324  0 24  ARG A N   1 ? 
ATOM   147  C  CA  . ARG A 1 24  ? 38.737 0.035   17.546 1.000 14.421  0 24  ARG A CA  1 ? 
ATOM   148  C  C   . ARG A 1 24  ? 40.088 -0.146  16.847 1.000 15.516  0 24  ARG A C   1 ? 
ATOM   149  O  O   . ARG A 1 24  ? 40.691 -1.218  16.932 1.000 14.501  0 24  ARG A O   1 ? 
ATOM   150  C  CB  . ARG A 1 24  ? 37.578 -0.076  16.544 1.000 14.139  0 24  ARG A CB  1 ? 
ATOM   151  C  CG  . ARG A 1 24  ? 37.567 -1.334  15.684 1.000 15.968  0 24  ARG A CG  1 ? 
ATOM   152  C  CD  . ARG A 1 24  ? 37.622 -2.596  16.464 1.000 16.300  0 24  ARG A CD  1 ? 
ATOM   153  N  NE  . ARG A 1 24  ? 37.484 -3.756  15.558 1.000 18.609  0 24  ARG A NE  1 ? 
ATOM   154  C  CZ  . ARG A 1 24  ? 37.869 -5.000  15.834 1.000 19.661  0 24  ARG A CZ  1 ? 
ATOM   155  N  NH1 . ARG A 1 24  ? 38.337 -5.337  17.014 1.000 20.435  0 24  ARG A NH1 1 ? 
ATOM   156  N  NH2 . ARG A 1 24  ? 37.781 -5.926  14.891 1.000 19.859  0 24  ARG A NH2 1 ? 
ATOM   157  N  N   . LYS A 1 25  ? 40.560 0.861   16.134 1.000 14.780  0 25  LYS A N   1 ? 
ATOM   158  C  CA  . LYS A 1 25  ? 41.862 0.757   15.485 1.000 15.444  0 25  LYS A CA  1 ? 
ATOM   159  C  C   . LYS A 1 25  ? 42.950 0.461   16.520 1.000 15.393  0 25  LYS A C   1 ? 
ATOM   160  O  O   . LYS A 1 25  ? 43.848 -0.352  16.276 1.000 16.452  0 25  LYS A O   1 ? 
ATOM   161  C  CB  . LYS A 1 25  ? 42.186 2.007   14.690 1.000 19.136  0 25  LYS A CB  1 ? 
ATOM   162  C  CG  . LYS A 1 25  ? 43.495 1.978   13.952 1.000 25.261  0 25  LYS A CG  1 ? 
ATOM   163  C  CD  . LYS A 1 25  ? 43.763 3.259   13.169 1.000 29.558  0 25  LYS A CD  1 ? 
ATOM   164  C  CE  . LYS A 1 25  ? 45.203 3.425   12.773 1.000 37.890  0 25  LYS A CE  1 ? 
ATOM   165  N  NZ  . LYS A 1 25  ? 45.806 2.152   12.348 1.000 42.195  0 25  LYS A NZ  1 ? 
ATOM   166  N  N   . ALA A 1 26  ? 42.882 1.131   17.691 1.000 14.454  0 26  ALA A N   1 ? 
ATOM   167  C  CA  . ALA A 1 26  ? 43.855 0.931   18.758 1.000 13.824  0 26  ALA A CA  1 ? 
ATOM   168  C  C   . ALA A 1 26  ? 43.893 -0.497  19.293 1.000 16.037  0 26  ALA A C   1 ? 
ATOM   169  O  O   . ALA A 1 26  ? 44.944 -0.937  19.764 1.000 15.016  0 26  ALA A O   1 ? 
ATOM   170  C  CB  . ALA A 1 26  ? 43.601 1.911   19.898 1.000 14.740  0 26  ALA A CB  1 ? 
ATOM   171  N  N   . MET A 1 27  ? 42.787 -1.256  19.223 1.000 14.072  0 27  MET A N   1 ? 
ATOM   172  C  CA  . MET A 1 27  ? 42.704 -2.565  19.850 1.000 13.193  0 27  MET A CA  1 ? 
ATOM   173  C  C   . MET A 1 27  ? 42.684 -3.742  18.851 1.000 14.294  0 27  MET A C   1 ? 
ATOM   174  O  O   . MET A 1 27  ? 43.005 -4.863  19.235 1.000 14.341  0 27  MET A O   1 ? 
ATOM   175  C  CB  . MET A 1 27  ? 41.459 -2.653  20.740 1.000 13.567  0 27  MET A CB  1 ? 
ATOM   176  C  CG  . MET A 1 27  ? 41.496 -1.718  21.926 1.000 15.446  0 27  MET A CG  1 ? 
ATOM   177  S  SD  . MET A 1 27  ? 40.106 -1.915  23.065 1.000 17.624  0 27  MET A SD  1 ? 
ATOM   178  C  CE  . MET A 1 27  ? 38.897 -0.902  22.222 1.000 15.623  0 27  MET A CE  1 ? 
ATOM   179  N  N   . LYS A 1 28  ? 42.321 -3.459  17.590 1.000 15.997  0 28  LYS A N   1 ? 
ATOM   180  C  CA  . LYS A 1 28  ? 42.140 -4.494  16.587 1.000 17.174  0 28  LYS A CA  1 ? 
ATOM   181  C  C   . LYS A 1 28  ? 43.462 -5.185  16.295 1.000 17.415  0 28  LYS A C   1 ? 
ATOM   182  O  O   . LYS A 1 28  ? 44.431 -4.519  15.994 1.000 19.064  0 28  LYS A O   1 ? 
ATOM   183  C  CB  . LYS A 1 28  ? 41.570 -3.910  15.298 1.000 18.901  0 28  LYS A CB  1 ? 
ATOM   184  C  CG  . LYS A 1 28  ? 41.160 -5.011  14.294 1.000 21.896  0 28  LYS A CG  1 ? 
ATOM   185  C  CD  . LYS A 1 28  ? 40.328 -4.528  13.116 1.000 26.258  0 28  LYS A CD  1 ? 
ATOM   186  C  CE  . LYS A 1 28  ? 40.517 -5.449  11.912 1.000 31.161  0 28  LYS A CE  1 ? 
ATOM   187  N  NZ  . LYS A 1 28  ? 40.210 -4.752  10.668 1.000 34.587  0 28  LYS A NZ  1 ? 
ATOM   188  N  N   . GLY A 1 29  ? 43.419 -6.522  16.296 1.000 18.788  0 29  GLY A N   1 ? 
ATOM   189  C  CA  . GLY A 1 29  ? 44.608 -7.284  15.944 1.000 19.837  0 29  GLY A CA  1 ? 
ATOM   190  C  C   . GLY A 1 29  ? 45.518 -7.406  17.155 1.000 19.418  0 29  GLY A C   1 ? 
ATOM   191  O  O   . GLY A 1 29  ? 45.256 -6.855  18.239 1.000 18.959  0 29  GLY A O   1 ? 
ATOM   192  N  N   . LEU A 1 30  ? 46.605 -8.139  16.969 1.000 16.488  0 30  LEU A N   1 ? 
ATOM   193  C  CA  . LEU A 1 30  ? 47.534 -8.343  18.063 1.000 15.949  0 30  LEU A CA  1 ? 
ATOM   194  C  C   . LEU A 1 30  ? 48.121 -7.016  18.502 1.000 15.517  0 30  LEU A C   1 ? 
ATOM   195  O  O   . LEU A 1 30  ? 48.529 -6.211  17.662 1.000 15.570  0 30  LEU A O   1 ? 
ATOM   196  C  CB  . LEU A 1 30  ? 48.654 -9.288  17.617 1.000 15.931  0 30  LEU A CB  1 ? 
ATOM   197  C  CG  . LEU A 1 30  ? 49.746 -9.524  18.669 1.000 15.194  0 30  LEU A CG  1 ? 
ATOM   198  C  CD1 . LEU A 1 30  ? 49.228 -10.108 19.948 1.000 16.334  0 30  LEU A CD1 1 ? 
ATOM   199  C  CD2 . LEU A 1 30  ? 50.807 -10.482 18.122 1.000 16.751  0 30  LEU A CD2 1 ? 
ATOM   200  N  N   . GLY A 1 31  ? 48.132 -6.824  19.823 1.000 13.851  0 31  GLY A N   1 ? 
ATOM   201  C  CA  . GLY A 1 31  ? 48.645 -5.618  20.451 1.000 14.424  0 31  GLY A CA  1 ? 
ATOM   202  C  C   . GLY A 1 31  ? 47.613 -4.504  20.571 1.000 14.955  0 31  GLY A C   1 ? 
ATOM   203  O  O   . GLY A 1 31  ? 46.462 -4.619  20.127 1.000 15.049  0 31  GLY A O   1 ? 
ATOM   204  N  N   . THR A 1 32  ? 48.071 -3.435  21.208 1.000 14.357  0 32  THR A N   1 ? 
ATOM   205  C  CA  . THR A 1 32  ? 47.222 -2.319  21.627 1.000 14.422  0 32  THR A CA  1 ? 
ATOM   206  C  C   . THR A 1 32  ? 48.015 -1.024  21.476 1.000 14.724  0 32  THR A C   1 ? 
ATOM   207  O  O   . THR A 1 32  ? 49.216 -0.951  21.758 1.000 15.481  0 32  THR A O   1 ? 
ATOM   208  C  CB  . THR A 1 32  ? 46.786 -2.529  23.088 1.000 15.864  0 32  THR A CB  1 ? 
ATOM   209  O  OG1 . THR A 1 32  ? 46.305 -3.854  23.279 1.000 16.899  0 32  THR A OG1 1 ? 
ATOM   210  C  CG2 . THR A 1 32  ? 45.709 -1.528  23.473 1.000 16.330  0 32  THR A CG2 1 ? 
ATOM   211  N  N   . ASP A 1 33  ? 47.346 0.029   20.982 1.000 14.630  0 33  ASP A N   1 ? 
ATOM   212  C  CA  . ASP A 1 33  ? 47.860 1.373   21.081 1.000 14.018  0 33  ASP A CA  1 ? 
ATOM   213  C  C   . ASP A 1 33  ? 47.301 2.049   22.339 1.000 15.274  0 33  ASP A C   1 ? 
ATOM   214  O  O   . ASP A 1 33  ? 46.271 2.691   22.262 1.000 14.299  0 33  ASP A O   1 ? 
ATOM   215  C  CB  . ASP A 1 33  ? 47.557 2.171   19.827 1.000 16.490  0 33  ASP A CB  1 ? 
ATOM   216  C  CG  . ASP A 1 33  ? 48.164 3.556   19.819 1.000 18.286  0 33  ASP A CG  1 ? 
ATOM   217  O  OD1 . ASP A 1 33  ? 48.735 3.974   20.840 1.000 16.949  0 33  ASP A OD1 1 ? 
ATOM   218  O  OD2 . ASP A 1 33  ? 48.098 4.181   18.748 1.000 20.069  0 33  ASP A OD2 1 ? 
ATOM   219  N  N   . GLU A 1 34  ? 47.953 1.865   23.483 1.000 15.123  0 34  GLU A N   1 ? 
ATOM   220  C  CA  . GLU A 1 34  ? 47.427 2.403   24.734 1.000 13.985  0 34  GLU A CA  1 ? 
ATOM   221  C  C   . GLU A 1 34  ? 47.408 3.940   24.708 1.000 14.551  0 34  GLU A C   1 ? 
ATOM   222  O  O   . GLU A 1 34  ? 46.535 4.573   25.305 1.000 13.903  0 34  GLU A O   1 ? 
ATOM   223  C  CB  . GLU A 1 34  ? 48.202 1.871   25.933 1.000 15.495  0 34  GLU A CB  1 ? 
ATOM   224  C  CG  . GLU A 1 34  ? 48.328 0.357   26.029 1.000 16.710  0 34  GLU A CG  1 ? 
ATOM   225  C  CD  . GLU A 1 34  ? 49.558 -0.226  25.348 1.000 17.822  0 34  GLU A CD  1 ? 
ATOM   226  O  OE1 . GLU A 1 34  ? 50.181 0.422   24.497 1.000 19.257  0 34  GLU A OE1 1 ? 
ATOM   227  O  OE2 . GLU A 1 34  ? 49.824 -1.400  25.689 1.000 24.076  0 34  GLU A OE2 1 ? 
ATOM   228  N  N   . ASP A 1 35  ? 48.409 4.534   24.061 1.000 15.038  0 35  ASP A N   1 ? 
ATOM   229  C  CA  . ASP A 1 35  ? 48.472 5.988   23.961 1.000 16.917  0 35  ASP A CA  1 ? 
ATOM   230  C  C   . ASP A 1 35  ? 47.213 6.540   23.282 1.000 16.797  0 35  ASP A C   1 ? 
ATOM   231  O  O   . ASP A 1 35  ? 46.664 7.551   23.743 1.000 16.911  0 35  ASP A O   1 ? 
ATOM   232  C  CB  . ASP A 1 35  ? 49.713 6.431   23.203 1.000 18.428  0 35  ASP A CB  1 ? 
ATOM   233  C  CG  . ASP A 1 35  ? 51.041 6.208   23.914 1.000 23.529  0 35  ASP A CG  1 ? 
ATOM   234  O  OD1 . ASP A 1 35  ? 51.073 6.294   25.146 1.000 25.812  0 35  ASP A OD1 1 ? 
ATOM   235  O  OD2 . ASP A 1 35  ? 52.058 6.030   23.205 1.000 30.978  0 35  ASP A OD2 1 ? 
ATOM   236  N  N   . ALA A 1 36  ? 46.792 5.919   22.180 1.000 14.701  0 36  ALA A N   1 ? 
ATOM   237  C  CA  . ALA A 1 36  ? 45.574 6.325   21.493 1.000 15.352  0 36  ALA A CA  1 ? 
ATOM   238  C  C   . ALA A 1 36  ? 44.352 6.224   22.409 1.000 14.680  0 36  ALA A C   1 ? 
ATOM   239  O  O   . ALA A 1 36  ? 43.489 7.125   22.405 1.000 15.478  0 36  ALA A O   1 ? 
ATOM   240  C  CB  . ALA A 1 36  ? 45.355 5.541   20.197 1.000 16.292  0 36  ALA A CB  1 ? 
ATOM   241  N  N   . ILE A 1 37  ? 44.243 5.131   23.195 1.000 13.678  0 37  ILE A N   1 ? 
ATOM   242  C  CA  . ILE A 1 37  ? 43.122 4.942   24.115 1.000 13.776  0 37  ILE A CA  1 ? 
ATOM   243  C  C   . ILE A 1 37  ? 43.080 6.107   25.122 1.000 14.638  0 37  ILE A C   1 ? 
ATOM   244  O  O   . ILE A 1 37  ? 42.031 6.712   25.366 1.000 14.408  0 37  ILE A O   1 ? 
ATOM   245  C  CB  . ILE A 1 37  ? 43.178 3.575   24.820 1.000 13.907  0 37  ILE A CB  1 ? 
ATOM   246  C  CG1 . ILE A 1 37  ? 42.945 2.402   23.863 1.000 13.806  0 37  ILE A CG1 1 ? 
ATOM   247  C  CG2 . ILE A 1 37  ? 42.197 3.473   25.988 1.000 14.339  0 37  ILE A CG2 1 ? 
ATOM   248  C  CD1 . ILE A 1 37  ? 43.246 1.043   24.449 1.000 13.757  0 37  ILE A CD1 1 ? 
ATOM   249  N  N   . ILE A 1 38  ? 44.246 6.472   25.690 1.000 13.419  0 38  ILE A N   1 ? 
ATOM   250  C  CA  . ILE A 1 38  ? 44.321 7.590   26.622 1.000 13.209  0 38  ILE A CA  1 ? 
ATOM   251  C  C   . ILE A 1 38  ? 43.962 8.891   25.919 1.000 14.053  0 38  ILE A C   1 ? 
ATOM   252  O  O   . ILE A 1 38  ? 43.207 9.681   26.483 1.000 14.972  0 38  ILE A O   1 ? 
ATOM   253  C  CB  . ILE A 1 38  ? 45.714 7.625   27.271 1.000 13.359  0 38  ILE A CB  1 ? 
ATOM   254  C  CG1 . ILE A 1 38  ? 46.012 6.358   28.075 1.000 14.071  0 38  ILE A CG1 1 ? 
ATOM   255  C  CG2 . ILE A 1 38  ? 45.898 8.911   28.097 1.000 14.196  0 38  ILE A CG2 1 ? 
ATOM   256  C  CD1 . ILE A 1 38  ? 47.469 6.262   28.515 1.000 14.563  0 38  ILE A CD1 1 ? 
ATOM   257  N  N   . SER A 1 39  ? 44.516 9.116   24.717 1.000 12.972  0 39  SER A N   1 ? 
ATOM   258  C  CA  . SER A 1 39  ? 44.333 10.364  24.005 1.000 14.793  0 39  SER A CA  1 ? 
ATOM   259  C  C   . SER A 1 39  ? 42.865 10.643  23.722 1.000 15.188  0 39  SER A C   1 ? 
ATOM   260  O  O   . SER A 1 39  ? 42.511 11.819  23.548 1.000 15.298  0 39  SER A O   1 ? 
ATOM   261  C  CB  . SER A 1 39  ? 45.059 10.312  22.736 1.000 17.265  0 39  SER A CB  1 ? 
ATOM   262  O  OG  . SER A 1 39  ? 44.329 9.588   21.753 1.000 24.810  0 39  SER A OG  1 ? 
ATOM   263  N  N   . VAL A 1 40  ? 42.048 9.593   23.569 1.000 14.077  0 40  VAL A N   1 ? 
ATOM   264  C  CA  . VAL A 1 40  ? 40.610 9.759   23.498 1.000 13.894  0 40  VAL A CA  1 ? 
ATOM   265  C  C   . VAL A 1 40  ? 39.975 9.888   24.888 1.000 13.892  0 40  VAL A C   1 ? 
ATOM   266  O  O   . VAL A 1 40  ? 39.391 10.924  25.242 1.000 15.118  0 40  VAL A O   1 ? 
ATOM   267  C  CB  . VAL A 1 40  ? 39.964 8.620   22.705 1.000 13.901  0 40  VAL A CB  1 ? 
ATOM   268  C  CG1 . VAL A 1 40  ? 38.448 8.763   22.741 1.000 15.462  0 40  VAL A CG1 1 ? 
ATOM   269  C  CG2 . VAL A 1 40  ? 40.464 8.601   21.259 1.000 14.994  0 40  VAL A CG2 1 ? 
ATOM   270  N  N   . LEU A 1 41  ? 40.052 8.822   25.688 1.000 13.515  0 41  LEU A N   1 ? 
ATOM   271  C  CA  . LEU A 1 41  ? 39.168 8.707   26.831 1.000 13.888  0 41  LEU A CA  1 ? 
ATOM   272  C  C   . LEU A 1 41  ? 39.487 9.715   27.940 1.000 14.831  0 41  LEU A C   1 ? 
ATOM   273  O  O   . LEU A 1 41  ? 38.564 10.145  28.666 1.000 13.874  0 41  LEU A O   1 ? 
ATOM   274  C  CB  . LEU A 1 41  ? 39.216 7.269   27.352 1.000 13.330  0 41  LEU A CB  1 ? 
ATOM   275  C  CG  . LEU A 1 41  ? 38.630 6.218   26.416 1.000 14.046  0 41  LEU A CG  1 ? 
ATOM   276  C  CD1 . LEU A 1 41  ? 38.775 4.871   27.108 1.000 15.291  0 41  LEU A CD1 1 ? 
ATOM   277  C  CD2 . LEU A 1 41  ? 37.165 6.472   26.006 1.000 14.171  0 41  LEU A CD2 1 ? 
ATOM   278  N  N   . ALA A 1 42  ? 40.782 10.042  28.134 1.000 14.492  0 42  ALA A N   1 ? 
ATOM   279  C  CA  . ALA A 1 42  ? 41.144 10.995  29.174 1.000 12.720  0 42  ALA A CA  1 ? 
ATOM   280  C  C   . ALA A 1 42  ? 40.853 12.439  28.792 1.000 13.637  0 42  ALA A C   1 ? 
ATOM   281  O  O   . ALA A 1 42  ? 41.062 13.352  29.600 1.000 13.914  0 42  ALA A O   1 ? 
ATOM   282  C  CB  . ALA A 1 42  ? 42.599 10.836  29.602 1.000 12.575  0 42  ALA A CB  1 ? 
ATOM   283  N  N   . TYR A 1 43  ? 40.463 12.693  27.540 1.000 13.902  0 43  TYR A N   1 ? 
ATOM   284  C  CA  . TYR A 1 43  ? 40.107 14.012  27.027 1.000 13.239  0 43  TYR A CA  1 ? 
ATOM   285  C  C   . TYR A 1 43  ? 38.619 14.126  26.668 1.000 13.259  0 43  TYR A C   1 ? 
ATOM   286  O  O   . TYR A 1 43  ? 38.222 15.020  25.902 1.000 14.604  0 43  TYR A O   1 ? 
ATOM   287  C  CB  . TYR A 1 43  ? 41.002 14.287  25.815 1.000 14.316  0 43  TYR A CB  1 ? 
ATOM   288  C  CG  . TYR A 1 43  ? 42.453 14.440  26.208 1.000 15.970  0 43  TYR A CG  1 ? 
ATOM   289  C  CD1 . TYR A 1 43  ? 42.955 15.668  26.576 1.000 18.901  0 43  TYR A CD1 1 ? 
ATOM   290  C  CD2 . TYR A 1 43  ? 43.262 13.333  26.326 1.000 17.335  0 43  TYR A CD2 1 ? 
ATOM   291  C  CE1 . TYR A 1 43  ? 44.261 15.792  27.042 1.000 20.112  0 43  TYR A CE1 1 ? 
ATOM   292  C  CE2 . TYR A 1 43  ? 44.580 13.449  26.719 1.000 19.988  0 43  TYR A CE2 1 ? 
ATOM   293  C  CZ  . TYR A 1 43  ? 45.065 14.679  27.080 1.000 19.181  0 43  TYR A CZ  1 ? 
ATOM   294  O  OH  . TYR A 1 43  ? 46.390 14.775  27.460 1.000 25.259  0 43  TYR A OH  1 ? 
ATOM   295  N  N   . ARG A 1 44  ? 37.803 13.274  27.271 1.000 12.936  0 44  ARG A N   1 ? 
ATOM   296  C  CA  . ARG A 1 44  ? 36.350 13.341  27.212 1.000 13.146  0 44  ARG A CA  1 ? 
ATOM   297  C  C   . ARG A 1 44  ? 35.833 13.264  28.647 1.000 15.032  0 44  ARG A C   1 ? 
ATOM   298  O  O   . ARG A 1 44  ? 36.474 12.641  29.537 1.000 17.263  0 44  ARG A O   1 ? 
ATOM   299  C  CB  . ARG A 1 44  ? 35.814 12.148  26.406 1.000 13.666  0 44  ARG A CB  1 ? 
ATOM   300  C  CG  . ARG A 1 44  ? 36.398 11.938  25.022 1.000 14.271  0 44  ARG A CG  1 ? 
ATOM   301  C  CD  . ARG A 1 44  ? 36.020 13.008  24.027 1.000 14.370  0 44  ARG A CD  1 ? 
ATOM   302  N  NE  . ARG A 1 44  ? 36.617 12.794  22.718 1.000 14.980  0 44  ARG A NE  1 ? 
ATOM   303  C  CZ  . ARG A 1 44  ? 37.877 13.101  22.372 1.000 14.850  0 44  ARG A CZ  1 ? 
ATOM   304  N  NH1 . ARG A 1 44  ? 38.612 13.908  23.118 1.000 16.325  0 44  ARG A NH1 1 ? 
ATOM   305  N  NH2 . ARG A 1 44  ? 38.408 12.603  21.284 1.000 17.187  0 44  ARG A NH2 1 ? 
ATOM   306  N  N   . ASN A 1 45  ? 34.658 13.835  28.938 1.000 12.967  0 45  ASN A N   1 ? 
ATOM   307  C  CA  . ASN A 1 45  ? 34.108 13.639  30.262 1.000 13.907  0 45  ASN A CA  1 ? 
ATOM   308  C  C   . ASN A 1 45  ? 33.277 12.359  30.348 1.000 12.923  0 45  ASN A C   1 ? 
ATOM   309  O  O   . ASN A 1 45  ? 33.125 11.623  29.379 1.000 13.069  0 45  ASN A O   1 ? 
ATOM   310  C  CB  . ASN A 1 45  ? 33.384 14.895  30.761 1.000 15.640  0 45  ASN A CB  1 ? 
ATOM   311  C  CG  . ASN A 1 45  ? 32.065 15.149  30.068 1.000 15.452  0 45  ASN A CG  1 ? 
ATOM   312  O  OD1 . ASN A 1 45  ? 31.586 14.334  29.285 1.000 15.141  0 45  ASN A OD1 1 ? 
ATOM   313  N  ND2 . ASN A 1 45  ? 31.422 16.264  30.394 1.000 20.333  0 45  ASN A ND2 1 ? 
ATOM   314  N  N   . THR A 1 46  ? 32.803 12.033  31.556 1.000 12.975  0 46  THR A N   1 ? 
ATOM   315  C  CA  . THR A 1 46  ? 32.155 10.747  31.788 1.000 14.068  0 46  THR A CA  1 ? 
ATOM   316  C  C   . THR A 1 46  ? 30.910 10.633  30.892 1.000 13.522  0 46  THR A C   1 ? 
ATOM   317  O  O   . THR A 1 46  ? 30.644 9.581   30.338 1.000 13.577  0 46  THR A O   1 ? 
ATOM   318  C  CB  . THR A 1 46  ? 31.811 10.562  33.277 1.000 16.107  0 46  THR A CB  1 ? 
ATOM   319  O  OG1 . THR A 1 46  ? 33.009 10.652  34.054 1.000 16.225  0 46  THR A OG1 1 ? 
ATOM   320  C  CG2 . THR A 1 46  ? 31.233 9.198   33.597 1.000 15.774  0 46  THR A CG2 1 ? 
ATOM   321  N  N   . ALA A 1 47  ? 30.119 11.705  30.764 1.000 14.279  0 47  ALA A N   1 ? 
ATOM   322  C  CA  . ALA A 1 47  ? 28.931 11.683  29.914 1.000 13.663  0 47  ALA A CA  1 ? 
ATOM   323  C  C   . ALA A 1 47  ? 29.306 11.426  28.460 1.000 13.528  0 47  ALA A C   1 ? 
ATOM   324  O  O   . ALA A 1 47  ? 28.621 10.664  27.789 1.000 14.027  0 47  ALA A O   1 ? 
ATOM   325  C  CB  . ALA A 1 47  ? 28.218 13.011  30.018 1.000 16.148  0 47  ALA A CB  1 ? 
ATOM   326  N  N   . GLN A 1 48  ? 30.364 12.080  27.959 1.000 12.231  0 48  GLN A N   1 ? 
ATOM   327  C  CA  . GLN A 1 48  ? 30.823 11.854  26.595 1.000 12.538  0 48  GLN A CA  1 ? 
ATOM   328  C  C   . GLN A 1 48  ? 31.266 10.404  26.410 1.000 11.626  0 48  GLN A C   1 ? 
ATOM   329  O  O   . GLN A 1 48  ? 30.997 9.791   25.389 1.000 13.162  0 48  GLN A O   1 ? 
ATOM   330  C  CB  . GLN A 1 48  ? 31.898 12.856  26.235 1.000 12.846  0 48  GLN A CB  1 ? 
ATOM   331  C  CG  . GLN A 1 48  ? 31.352 14.268  26.041 1.000 13.379  0 48  GLN A CG  1 ? 
ATOM   332  C  CD  . GLN A 1 48  ? 32.414 15.274  25.710 1.000 14.571  0 48  GLN A CD  1 ? 
ATOM   333  O  OE1 . GLN A 1 48  ? 33.556 15.178  26.178 1.000 15.161  0 48  GLN A OE1 1 ? 
ATOM   334  N  NE2 . GLN A 1 48  ? 31.998 16.319  25.006 1.000 14.283  0 48  GLN A NE2 1 ? 
ATOM   335  N  N   . ARG A 1 49  ? 31.929 9.825   27.403 1.000 11.018  0 49  ARG A N   1 ? 
ATOM   336  C  CA  . ARG A 1 49  ? 32.353 8.438   27.323 1.000 11.419  0 49  ARG A CA  1 ? 
ATOM   337  C  C   . ARG A 1 49  ? 31.156 7.510   27.101 1.000 13.060  0 49  ARG A C   1 ? 
ATOM   338  O  O   . ARG A 1 49  ? 31.260 6.480   26.435 1.000 12.241  0 49  ARG A O   1 ? 
ATOM   339  C  CB  . ARG A 1 49  ? 33.240 8.062   28.510 1.000 11.772  0 49  ARG A CB  1 ? 
ATOM   340  C  CG  . ARG A 1 49  ? 34.557 8.814   28.603 1.000 12.311  0 49  ARG A CG  1 ? 
ATOM   341  C  CD  . ARG A 1 49  ? 35.314 8.276   29.784 1.000 13.541  0 49  ARG A CD  1 ? 
ATOM   342  N  NE  . ARG A 1 49  ? 36.333 9.236   30.205 1.000 12.387  0 49  ARG A NE  1 ? 
ATOM   343  C  CZ  . ARG A 1 49  ? 36.390 9.864   31.375 1.000 13.591  0 49  ARG A CZ  1 ? 
ATOM   344  N  NH1 . ARG A 1 49  ? 37.234 10.867  31.488 1.000 15.804  0 49  ARG A NH1 1 ? 
ATOM   345  N  NH2 . ARG A 1 49  ? 35.579 9.551   32.350 1.000 13.894  0 49  ARG A NH2 1 ? 
ATOM   346  N  N   . GLN A 1 50  ? 30.013 7.831   27.697 1.000 12.268  0 50  GLN A N   1 ? 
ATOM   347  C  CA  . GLN A 1 50  ? 28.827 6.990   27.536 1.000 14.057  0 50  GLN A CA  1 ? 
ATOM   348  C  C   . GLN A 1 50  ? 28.325 7.060   26.095 1.000 12.696  0 50  GLN A C   1 ? 
ATOM   349  O  O   . GLN A 1 50  ? 27.853 6.041   25.567 1.000 14.802  0 50  GLN A O   1 ? 
ATOM   350  C  CB  . GLN A 1 50  ? 27.731 7.398   28.524 1.000 15.356  0 50  GLN A CB  1 ? 
ATOM   351  C  CG  . GLN A 1 50  ? 28.144 7.429   29.994 1.000 15.120  0 50  GLN A CG  1 ? 
ATOM   352  C  CD  . GLN A 1 50  ? 29.060 6.286   30.396 1.000 15.512  0 50  GLN A CD  1 ? 
ATOM   353  O  OE1 . GLN A 1 50  ? 30.188 6.459   30.915 1.000 16.286  0 50  GLN A OE1 1 ? 
ATOM   354  N  NE2 . GLN A 1 50  ? 28.537 5.099   30.254 1.000 12.734  0 50  GLN A NE2 1 ? 
ATOM   355  N  N   . GLU A 1 51  ? 28.441 8.230   25.463 1.000 14.148  0 51  GLU A N   1 ? 
ATOM   356  C  CA  . GLU A 1 51  ? 28.051 8.406   24.072 1.000 14.697  0 51  GLU A CA  1 ? 
ATOM   357  C  C   . GLU A 1 51  ? 29.006 7.622   23.188 1.000 13.633  0 51  GLU A C   1 ? 
ATOM   358  O  O   . GLU A 1 51  ? 28.614 7.096   22.158 1.000 13.542  0 51  GLU A O   1 ? 
ATOM   359  C  CB  . GLU A 1 51  ? 28.012 9.878   23.729 1.000 16.355  0 51  GLU A CB  1 ? 
ATOM   360  C  CG  . GLU A 1 51  ? 26.934 10.618  24.514 1.000 20.980  0 51  GLU A CG  1 ? 
ATOM   361  C  CD  . GLU A 1 51  ? 25.579 10.724  23.891 1.000 30.707  0 51  GLU A CD  1 ? 
ATOM   362  O  OE1 . GLU A 1 51  ? 25.335 10.162  22.802 1.000 32.441  0 51  GLU A OE1 1 ? 
ATOM   363  O  OE2 . GLU A 1 51  ? 24.814 11.502  24.509 1.000 35.822  0 51  GLU A OE2 1 ? 
ATOM   364  N  N   . ILE A 1 52  ? 30.282 7.514   23.573 1.000 12.982  0 52  ILE A N   1 ? 
ATOM   365  C  CA  . ILE A 1 52  ? 31.217 6.697   22.802 1.000 13.225  0 52  ILE A CA  1 ? 
ATOM   366  C  C   . ILE A 1 52  ? 30.817 5.220   22.898 1.000 12.514  0 52  ILE A C   1 ? 
ATOM   367  O  O   . ILE A 1 52  ? 30.879 4.507   21.908 1.000 13.653  0 52  ILE A O   1 ? 
ATOM   368  C  CB  . ILE A 1 52  ? 32.680 6.884   23.253 1.000 12.022  0 52  ILE A CB  1 ? 
ATOM   369  C  CG1 . ILE A 1 52  ? 33.114 8.313   23.083 1.000 12.539  0 52  ILE A CG1 1 ? 
ATOM   370  C  CG2 . ILE A 1 52  ? 33.604 5.949   22.465 1.000 12.650  0 52  ILE A CG2 1 ? 
ATOM   371  C  CD1 . ILE A 1 52  ? 34.460 8.657   23.688 1.000 13.525  0 52  ILE A CD1 1 ? 
ATOM   372  N  N   . ARG A 1 53  ? 30.397 4.752   24.070 1.000 12.726  0 53  ARG A N   1 ? 
ATOM   373  C  CA  . ARG A 1 53  ? 29.954 3.359   24.218 1.000 12.534  0 53  ARG A CA  1 ? 
ATOM   374  C  C   . ARG A 1 53  ? 28.793 3.076   23.272 1.000 13.535  0 53  ARG A C   1 ? 
ATOM   375  O  O   . ARG A 1 53  ? 28.741 2.024   22.619 1.000 13.836  0 53  ARG A O   1 ? 
ATOM   376  C  CB  . ARG A 1 53  ? 29.521 2.992   25.638 1.000 14.544  0 53  ARG A CB  1 ? 
ATOM   377  C  CG  . ARG A 1 53  ? 30.609 3.018   26.691 1.000 15.291  0 53  ARG A CG  1 ? 
ATOM   378  C  CD  . ARG A 1 53  ? 30.081 2.934   28.108 1.000 16.437  0 53  ARG A CD  1 ? 
ATOM   379  N  NE  . ARG A 1 53  ? 29.487 1.618   28.360 1.000 16.783  0 53  ARG A NE  1 ? 
ATOM   380  C  CZ  . ARG A 1 53  ? 28.921 1.254   29.503 1.000 18.807  0 53  ARG A CZ  1 ? 
ATOM   381  N  NH1 . ARG A 1 53  ? 28.695 2.156   30.435 1.000 20.169  0 53  ARG A NH1 1 ? 
ATOM   382  N  NH2 . ARG A 1 53  ? 28.517 0.011   29.709 1.000 19.404  0 53  ARG A NH2 1 ? 
ATOM   383  N  N   . THR A 1 54  ? 27.835 4.009   23.210 1.000 15.102  0 54  THR A N   1 ? 
ATOM   384  C  CA  . THR A 1 54  ? 26.682 3.818   22.343 1.000 15.864  0 54  THR A CA  1 ? 
ATOM   385  C  C   . THR A 1 54  ? 27.140 3.790   20.886 1.000 15.549  0 54  THR A C   1 ? 
ATOM   386  O  O   . THR A 1 54  ? 26.724 2.914   20.110 1.000 14.700  0 54  THR A O   1 ? 
ATOM   387  C  CB  . THR A 1 54  ? 25.656 4.921   22.597 1.000 15.782  0 54  THR A CB  1 ? 
ATOM   388  O  OG1 . THR A 1 54  ? 25.286 4.805   23.966 1.000 19.266  0 54  THR A OG1 1 ? 
ATOM   389  C  CG2 . THR A 1 54  ? 24.439 4.743   21.707 1.000 18.833  0 54  THR A CG2 1 ? 
ATOM   390  N  N   . ALA A 1 55  ? 27.989 4.736   20.487 1.000 14.619  0 55  ALA A N   1 ? 
ATOM   391  C  CA  . ALA A 1 55  ? 28.509 4.819   19.127 1.000 14.526  0 55  ALA A CA  1 ? 
ATOM   392  C  C   . ALA A 1 55  ? 29.327 3.587   18.762 1.000 14.581  0 55  ALA A C   1 ? 
ATOM   393  O  O   . ALA A 1 55  ? 29.377 3.167   17.581 1.000 15.066  0 55  ALA A O   1 ? 
ATOM   394  C  CB  . ALA A 1 55  ? 29.323 6.069   18.873 1.000 15.221  0 55  ALA A CB  1 ? 
ATOM   395  N  N   . TYR A 1 56  ? 30.093 3.046   19.719 1.000 14.219  0 56  TYR A N   1 ? 
ATOM   396  C  CA  . TYR A 1 56  ? 30.903 1.871   19.423 1.000 14.272  0 56  TYR A CA  1 ? 
ATOM   397  C  C   . TYR A 1 56  ? 30.022 0.677   19.049 1.000 13.683  0 56  TYR A C   1 ? 
ATOM   398  O  O   . TYR A 1 56  ? 30.307 -0.027  18.089 1.000 15.173  0 56  TYR A O   1 ? 
ATOM   399  C  CB  . TYR A 1 56  ? 31.784 1.586   20.628 1.000 14.085  0 56  TYR A CB  1 ? 
ATOM   400  C  CG  . TYR A 1 56  ? 32.949 0.624   20.439 1.000 12.976  0 56  TYR A CG  1 ? 
ATOM   401  C  CD1 . TYR A 1 56  ? 34.196 1.082   20.020 1.000 13.912  0 56  TYR A CD1 1 ? 
ATOM   402  C  CD2 . TYR A 1 56  ? 32.860 -0.717  20.773 1.000 15.028  0 56  TYR A CD2 1 ? 
ATOM   403  C  CE1 . TYR A 1 56  ? 35.287 0.242   19.910 1.000 13.427  0 56  TYR A CE1 1 ? 
ATOM   404  C  CE2 . TYR A 1 56  ? 33.950 -1.576  20.688 1.000 15.209  0 56  TYR A CE2 1 ? 
ATOM   405  C  CZ  . TYR A 1 56  ? 35.168 -1.093  20.244 1.000 15.628  0 56  TYR A CZ  1 ? 
ATOM   406  O  OH  . TYR A 1 56  ? 36.286 -1.882  20.100 1.000 17.659  0 56  TYR A OH  1 ? 
ATOM   407  N  N   . LYS A 1 57  ? 28.890 0.505   19.722 1.000 13.914  0 57  LYS A N   1 ? 
ATOM   408  C  CA  . LYS A 1 57  ? 27.992 -0.576  19.350 1.000 14.941  0 57  LYS A CA  1 ? 
ATOM   409  C  C   . LYS A 1 57  ? 27.457 -0.367  17.934 1.000 17.133  0 57  LYS A C   1 ? 
ATOM   410  O  O   . LYS A 1 57  ? 27.472 -1.290  17.127 1.000 17.279  0 57  LYS A O   1 ? 
ATOM   411  C  CB  . LYS A 1 57  ? 26.841 -0.677  20.341 1.000 15.807  0 57  LYS A CB  1 ? 
ATOM   412  C  CG  . LYS A 1 57  ? 27.254 -1.179  21.711 1.000 17.799  0 57  LYS A CG  1 ? 
ATOM   413  C  CD  . LYS A 1 57  ? 26.034 -1.321  22.611 1.000 23.564  0 57  LYS A CD  1 ? 
ATOM   414  C  CE  . LYS A 1 57  ? 26.360 -1.971  23.904 1.000 28.821  0 57  LYS A CE  1 ? 
ATOM   415  N  NZ  . LYS A 1 57  ? 25.134 -1.980  24.718 1.000 31.692  0 57  LYS A NZ  1 ? 
ATOM   416  N  N   . SER A 1 58  ? 27.051 0.871   17.592 1.000 18.307  0 58  SER A N   1 ? 
ATOM   417  C  CA  . SER A 1 58  ? 26.395 1.092   16.313 1.000 18.780  0 58  SER A CA  1 ? 
ATOM   418  C  C   . SER A 1 58  ? 27.385 1.244   15.171 1.000 19.372  0 58  SER A C   1 ? 
ATOM   419  O  O   . SER A 1 58  ? 27.039 1.035   14.006 1.000 21.996  0 58  SER A O   1 ? 
ATOM   420  C  CB  . SER A 1 58  ? 25.465 2.264   16.379 1.000 22.068  0 58  SER A CB  1 ? 
ATOM   421  O  OG  . SER A 1 58  ? 26.221 3.430   16.603 1.000 23.609  0 58  SER A OG  1 ? 
ATOM   422  N  N   . THR A 1 59  ? 28.622 1.658   15.436 1.000 17.822  0 59  THR A N   1 ? 
ATOM   423  C  CA  . THR A 1 59  ? 29.586 1.910   14.368 1.000 18.744  0 59  THR A CA  1 ? 
ATOM   424  C  C   . THR A 1 59  ? 30.581 0.765   14.183 1.000 18.373  0 59  THR A C   1 ? 
ATOM   425  O  O   . THR A 1 59  ? 31.125 0.603   13.090 1.000 19.759  0 59  THR A O   1 ? 
ATOM   426  C  CB  . THR A 1 59  ? 30.352 3.201   14.607 1.000 22.541  0 59  THR A CB  1 ? 
ATOM   427  O  OG1 . THR A 1 59  ? 31.230 3.060   15.705 1.000 37.233  0 59  THR A OG1 1 ? 
ATOM   428  C  CG2 . THR A 1 59  ? 29.408 4.317   14.968 1.000 19.380  0 59  THR A CG2 1 ? 
ATOM   429  N  N   . ILE A 1 60  ? 30.901 0.067   15.283 1.000 15.360  0 60  ILE A N   1 ? 
ATOM   430  C  CA  . ILE A 1 60  ? 31.913 -0.978  15.259 1.000 16.083  0 60  ILE A CA  1 ? 
ATOM   431  C  C   . ILE A 1 60  ? 31.261 -2.357  15.362 1.000 17.138  0 60  ILE A C   1 ? 
ATOM   432  O  O   . ILE A 1 60  ? 31.887 -3.365  15.043 1.000 18.728  0 60  ILE A O   1 ? 
ATOM   433  C  CB  . ILE A 1 60  ? 32.930 -0.765  16.401 1.000 15.522  0 60  ILE A CB  1 ? 
ATOM   434  C  CG1 . ILE A 1 60  ? 33.523 0.637   16.402 1.000 14.948  0 60  ILE A CG1 1 ? 
ATOM   435  C  CG2 . ILE A 1 60  ? 34.038 -1.821  16.415 1.000 16.132  0 60  ILE A CG2 1 ? 
ATOM   436  C  CD1 . ILE A 1 60  ? 34.154 1.083   15.120 1.000 14.990  0 60  ILE A CD1 1 ? 
ATOM   437  N  N   . GLY A 1 61  ? 30.053 -2.438  15.900 1.000 16.305  0 61  GLY A N   1 ? 
ATOM   438  C  CA  . GLY A 1 61  ? 29.391 -3.731  16.041 1.000 17.072  0 61  GLY A CA  1 ? 
ATOM   439  C  C   . GLY A 1 61  ? 29.937 -4.565  17.198 1.000 17.242  0 61  GLY A C   1 ? 
ATOM   440  O  O   . GLY A 1 61  ? 29.869 -5.801  17.152 1.000 18.802  0 61  GLY A O   1 ? 
ATOM   441  N  N   . ARG A 1 62  ? 30.486 -3.893  18.216 1.000 16.229  0 62  ARG A N   1 ? 
ATOM   442  C  CA  . ARG A 1 62  ? 31.176 -4.536  19.331 1.000 17.498  0 62  ARG A CA  1 ? 
ATOM   443  C  C   . ARG A 1 62  ? 30.856 -3.775  20.602 1.000 16.155  0 62  ARG A C   1 ? 
ATOM   444  O  O   . ARG A 1 62  ? 30.205 -2.741  20.546 1.000 14.776  0 62  ARG A O   1 ? 
ATOM   445  C  CB  . ARG A 1 62  ? 32.689 -4.599  19.083 1.000 16.340  0 62  ARG A CB  1 ? 
ATOM   446  C  CG  . ARG A 1 62  ? 33.163 -5.383  17.868 1.000 15.860  0 62  ARG A CG  1 ? 
ATOM   447  C  CD  . ARG A 1 62  ? 34.659 -5.304  17.687 1.000 17.787  0 62  ARG A CD  1 ? 
ATOM   448  N  NE  . ARG A 1 62  ? 35.368 -6.017  18.758 1.000 18.223  0 62  ARG A NE  1 ? 
ATOM   449  C  CZ  . ARG A 1 62  ? 35.974 -7.181  18.587 1.000 19.342  0 62  ARG A CZ  1 ? 
ATOM   450  N  NH1 . ARG A 1 62  ? 35.798 -7.906  17.493 1.000 21.349  0 62  ARG A NH1 1 ? 
ATOM   451  N  NH2 . ARG A 1 62  ? 36.686 -7.682  19.560 1.000 20.046  0 62  ARG A NH2 1 ? 
ATOM   452  N  N   . ASP A 1 63  ? 31.266 -4.294  21.767 1.000 15.621  0 63  ASP A N   1 ? 
ATOM   453  C  CA  . ASP A 1 63  ? 31.030 -3.685  23.054 1.000 16.964  0 63  ASP A CA  1 ? 
ATOM   454  C  C   . ASP A 1 63  ? 32.344 -3.115  23.589 1.000 16.255  0 63  ASP A C   1 ? 
ATOM   455  O  O   . ASP A 1 63  ? 33.337 -3.850  23.738 1.000 16.206  0 63  ASP A O   1 ? 
ATOM   456  C  CB  . ASP A 1 63  ? 30.548 -4.692  24.091 1.000 19.736  0 63  ASP A CB  1 ? 
ATOM   457  C  CG  . ASP A 1 63  ? 30.059 -4.033  25.389 1.000 28.786  0 63  ASP A CG  1 ? 
ATOM   458  O  OD1 . ASP A 1 63  ? 30.892 -3.541  26.274 1.000 25.649  0 63  ASP A OD1 1 ? 
ATOM   459  O  OD2 . ASP A 1 63  ? 28.806 -3.918  25.513 1.000 41.199  0 63  ASP A OD2 1 ? 
ATOM   460  N  N   . LEU A 1 64  ? 32.324 -1.810  23.898 1.000 14.735  0 64  LEU A N   1 ? 
ATOM   461  C  CA  . LEU A 1 64  ? 33.556 -1.109  24.249 1.000 13.818  0 64  LEU A CA  1 ? 
ATOM   462  C  C   . LEU A 1 64  ? 34.148 -1.572  25.579 1.000 15.459  0 64  LEU A C   1 ? 
ATOM   463  O  O   . LEU A 1 64  ? 35.364 -1.769  25.645 1.000 14.245  0 64  LEU A O   1 ? 
ATOM   464  C  CB  . LEU A 1 64  ? 33.266 0.388   24.244 1.000 13.714  0 64  LEU A CB  1 ? 
ATOM   465  C  CG  . LEU A 1 64  ? 34.441 1.320   24.572 1.000 14.226  0 64  LEU A CG  1 ? 
ATOM   466  C  CD1 . LEU A 1 64  ? 35.671 0.958   23.726 1.000 14.052  0 64  LEU A CD1 1 ? 
ATOM   467  C  CD2 . LEU A 1 64  ? 34.069 2.773   24.369 1.000 13.922  0 64  LEU A CD2 1 ? 
ATOM   468  N  N   . ILE A 1 65  ? 33.350 -1.607  26.641 1.000 17.977  0 65  ILE A N   1 ? 
ATOM   469  C  CA  . ILE A 1 65  ? 33.871 -1.994  27.955 1.000 19.005  0 65  ILE A CA  1 ? 
ATOM   470  C  C   . ILE A 1 65  ? 34.404 -3.424  27.860 1.000 18.963  0 65  ILE A C   1 ? 
ATOM   471  O  O   . ILE A 1 65  ? 35.471 -3.706  28.402 1.000 18.895  0 65  ILE A O   1 ? 
ATOM   472  C  CB  . ILE A 1 65  ? 32.826 -1.979  29.083 1.000 22.838  0 65  ILE A CB  1 ? 
ATOM   473  C  CG1 . ILE A 1 65  ? 32.070 -0.709  29.173 1.000 29.701  0 65  ILE A CG1 1 ? 
ATOM   474  C  CG2 . ILE A 1 65  ? 33.474 -2.373  30.422 1.000 21.656  0 65  ILE A CG2 1 ? 
ATOM   475  C  CD1 . ILE A 1 65  ? 32.953 0.453   29.437 1.000 25.940  0 65  ILE A CD1 1 ? 
ATOM   476  N  N   . ASP A 1 66  ? 33.665 -4.321  27.191 1.000 20.314  0 66  ASP A N   1 ? 
ATOM   477  C  CA  . ASP A 1 66  ? 34.115 -5.701  27.044 1.000 20.038  0 66  ASP A CA  1 ? 
ATOM   478  C  C   . ASP A 1 66  ? 35.465 -5.768  26.333 1.000 18.220  0 66  ASP A C   1 ? 
ATOM   479  O  O   . ASP A 1 66  ? 36.382 -6.466  26.787 1.000 18.865  0 66  ASP A O   1 ? 
ATOM   480  C  CB  . ASP A 1 66  ? 33.151 -6.569  26.256 1.000 23.074  0 66  ASP A CB  1 ? 
ATOM   481  C  CG  . ASP A 1 66  ? 31.834 -6.886  26.939 1.000 28.506  0 66  ASP A CG  1 ? 
ATOM   482  O  OD1 . ASP A 1 66  ? 31.700 -6.577  28.140 1.000 32.656  0 66  ASP A OD1 1 ? 
ATOM   483  O  OD2 . ASP A 1 66  ? 30.939 -7.406  26.243 1.000 32.579  0 66  ASP A OD2 1 ? 
ATOM   484  N  N   . ASP A 1 67  ? 35.624 -4.991  25.263 1.000 16.297  0 67  ASP A N   1 ? 
ATOM   485  C  CA  . ASP A 1 67  ? 36.867 -4.967  24.524 1.000 16.005  0 67  ASP A CA  1 ? 
ATOM   486  C  C   . ASP A 1 67  ? 37.988 -4.426  25.405 1.000 16.499  0 67  ASP A C   1 ? 
ATOM   487  O  O   . ASP A 1 67  ? 39.098 -4.962  25.376 1.000 16.016  0 67  ASP A O   1 ? 
ATOM   488  C  CB  . ASP A 1 67  ? 36.764 -4.239  23.198 1.000 16.043  0 67  ASP A CB  1 ? 
ATOM   489  C  CG  . ASP A 1 67  ? 36.009 -4.994  22.102 1.000 17.665  0 67  ASP A CG  1 ? 
ATOM   490  O  OD1 . ASP A 1 67  ? 35.596 -6.153  22.360 1.000 20.471  0 67  ASP A OD1 1 ? 
ATOM   491  O  OD2 . ASP A 1 67  ? 35.863 -4.427  21.013 1.000 18.146  0 67  ASP A OD2 1 ? 
ATOM   492  N  N   . LEU A 1 68  ? 37.755 -3.328  26.150 1.000 14.840  0 68  LEU A N   1 ? 
ATOM   493  C  CA  . LEU A 1 68  ? 38.829 -2.754  26.953 1.000 14.846  0 68  LEU A CA  1 ? 
ATOM   494  C  C   . LEU A 1 68  ? 39.254 -3.709  28.066 1.000 15.959  0 68  LEU A C   1 ? 
ATOM   495  O  O   . LEU A 1 68  ? 40.430 -3.830  28.398 1.000 16.519  0 68  LEU A O   1 ? 
ATOM   496  C  CB  . LEU A 1 68  ? 38.333 -1.443  27.563 1.000 14.503  0 68  LEU A CB  1 ? 
ATOM   497  C  CG  . LEU A 1 68  ? 38.180 -0.264  26.600 1.000 12.922  0 68  LEU A CG  1 ? 
ATOM   498  C  CD1 . LEU A 1 68  ? 37.292 0.822   27.269 1.000 13.183  0 68  LEU A CD1 1 ? 
ATOM   499  C  CD2 . LEU A 1 68  ? 39.498 0.314   26.195 1.000 13.897  0 68  LEU A CD2 1 ? 
ATOM   500  N  N   . LYS A 1 69  ? 38.287 -4.405  28.668 1.000 15.904  0 69  LYS A N   1 ? 
ATOM   501  C  CA  . LYS A 1 69  ? 38.608 -5.380  29.707 1.000 16.306  0 69  LYS A CA  1 ? 
ATOM   502  C  C   . LYS A 1 69  ? 39.453 -6.523  29.152 1.000 18.616  0 69  LYS A C   1 ? 
ATOM   503  O  O   . LYS A 1 69  ? 40.361 -6.969  29.850 1.000 19.704  0 69  LYS A O   1 ? 
ATOM   504  C  CB  . LYS A 1 69  ? 37.357 -5.953  30.346 1.000 16.545  0 69  LYS A CB  1 ? 
ATOM   505  C  CG  . LYS A 1 69  ? 36.661 -5.030  31.275 1.000 19.094  0 69  LYS A CG  1 ? 
ATOM   506  C  CD  . LYS A 1 69  ? 35.354 -5.529  31.877 1.000 21.995  0 69  LYS A CD  1 ? 
ATOM   507  C  CE  . LYS A 1 69  ? 34.898 -4.637  32.963 1.000 25.274  0 69  LYS A CE  1 ? 
ATOM   508  N  NZ  . LYS A 1 69  ? 33.562 -5.017  33.418 1.000 28.819  0 69  LYS A NZ  1 ? 
ATOM   509  N  N   . SER A 1 70  ? 39.169 -6.963  27.935 1.000 19.161  0 70  SER A N   1 ? 
ATOM   510  C  CA  . SER A 1 70  ? 39.902 -8.040  27.288 1.000 20.065  0 70  SER A CA  1 ? 
ATOM   511  C  C   . SER A 1 70  ? 41.318 -7.596  26.910 1.000 18.392  0 70  SER A C   1 ? 
ATOM   512  O  O   . SER A 1 70  ? 42.263 -8.366  27.034 1.000 20.299  0 70  SER A O   1 ? 
ATOM   513  C  CB  . SER A 1 70  ? 39.110 -8.571  26.107 1.000 22.032  0 70  SER A CB  1 ? 
ATOM   514  O  OG  . SER A 1 70  ? 39.914 -9.513  25.425 1.000 28.362  0 70  SER A OG  1 ? 
ATOM   515  N  N   . GLU A 1 71  ? 41.491 -6.348  26.444 1.000 16.017  0 71  GLU A N   1 ? 
ATOM   516  C  CA  . GLU A 1 71  ? 42.752 -5.858  25.934 1.000 17.138  0 71  GLU A CA  1 ? 
ATOM   517  C  C   . GLU A 1 71  ? 43.704 -5.467  27.050 1.000 15.614  0 71  GLU A C   1 ? 
ATOM   518  O  O   . GLU A 1 71  ? 44.887 -5.695  26.943 1.000 17.565  0 71  GLU A O   1 ? 
ATOM   519  C  CB  . GLU A 1 71  ? 42.613 -4.583  25.096 1.000 19.373  0 71  GLU A CB  1 ? 
ATOM   520  C  CG  . GLU A 1 71  ? 42.057 -4.866  23.720 1.000 25.538  0 71  GLU A CG  1 ? 
ATOM   521  C  CD  . GLU A 1 71  ? 43.025 -5.404  22.721 1.000 19.091  0 71  GLU A CD  1 ? 
ATOM   522  O  OE1 . GLU A 1 71  ? 44.114 -4.854  22.381 1.000 18.539  0 71  GLU A OE1 1 ? 
ATOM   523  O  OE2 . GLU A 1 71  ? 42.533 -6.369  22.149 1.000 26.152  0 71  GLU A OE2 1 ? 
ATOM   524  N  N   . LEU A 1 72  ? 43.194 -4.866  28.119 1.000 15.372  0 72  LEU A N   1 ? 
ATOM   525  C  CA  . LEU A 1 72  ? 44.016 -4.231  29.144 1.000 15.546  0 72  LEU A CA  1 ? 
ATOM   526  C  C   . LEU A 1 72  ? 44.101 -5.117  30.379 1.000 18.475  0 72  LEU A C   1 ? 
ATOM   527  O  O   . LEU A 1 72  ? 43.217 -5.944  30.595 1.000 20.514  0 72  LEU A O   1 ? 
ATOM   528  C  CB  . LEU A 1 72  ? 43.443 -2.860  29.488 1.000 15.205  0 72  LEU A CB  1 ? 
ATOM   529  C  CG  . LEU A 1 72  ? 43.177 -1.923  28.300 1.000 15.374  0 72  LEU A CG  1 ? 
ATOM   530  C  CD1 . LEU A 1 72  ? 42.632 -0.622  28.885 1.000 15.727  0 72  LEU A CD1 1 ? 
ATOM   531  C  CD2 . LEU A 1 72  ? 44.458 -1.743  27.512 1.000 16.084  0 72  LEU A CD2 1 ? 
ATOM   532  N  N   . SER A 1 73  ? 45.090 -4.838  31.228 1.000 16.380  0 73  SER A N   1 ? 
ATOM   533  C  CA  . SER A 1 73  ? 45.287 -5.553  32.467 1.000 17.332  0 73  SER A CA  1 ? 
ATOM   534  C  C   . SER A 1 73  ? 45.658 -4.586  33.586 1.000 15.731  0 73  SER A C   1 ? 
ATOM   535  O  O   . SER A 1 73  ? 46.095 -3.469  33.363 1.000 16.515  0 73  SER A O   1 ? 
ATOM   536  C  CB  . SER A 1 73  ? 46.363 -6.630  32.317 1.000 21.119  0 73  SER A CB  1 ? 
ATOM   537  O  OG  . SER A 1 73  ? 47.571 -6.019  31.858 1.000 29.843  0 73  SER A OG  1 ? 
ATOM   538  N  N   . GLY A 1 74  ? 45.554 -5.116  34.808 1.000 16.570  0 74  GLY A N   1 ? 
ATOM   539  C  CA  . GLY A 1 74  ? 46.126 -4.476  35.978 1.000 16.768  0 74  GLY A CA  1 ? 
ATOM   540  C  C   . GLY A 1 74  ? 45.563 -3.088  36.265 1.000 16.184  0 74  GLY A C   1 ? 
ATOM   541  O  O   . GLY A 1 74  ? 44.370 -2.835  36.074 1.000 15.298  0 74  GLY A O   1 ? 
ATOM   542  N  N   . ASN A 1 75  ? 46.429 -2.237  36.826 1.000 15.425  0 75  ASN A N   1 ? 
ATOM   543  C  CA  . ASN A 1 75  ? 46.004 -0.947  37.322 1.000 14.715  0 75  ASN A CA  1 ? 
ATOM   544  C  C   . ASN A 1 75  ? 45.547 -0.100  36.148 1.000 13.671  0 75  ASN A C   1 ? 
ATOM   545  O  O   . ASN A 1 75  ? 44.601 0.667   36.296 1.000 13.791  0 75  ASN A O   1 ? 
ATOM   546  C  CB  . ASN A 1 75  ? 47.088 -0.259  38.151 1.000 15.784  0 75  ASN A CB  1 ? 
ATOM   547  C  CG  . ASN A 1 75  ? 47.342 -0.987  39.460 1.000 19.881  0 75  ASN A CG  1 ? 
ATOM   548  O  OD1 . ASN A 1 75  ? 48.496 -1.176  39.887 1.000 25.744  0 75  ASN A OD1 1 ? 
ATOM   549  N  ND2 . ASN A 1 75  ? 46.297 -1.364  40.129 1.000 18.232  0 75  ASN A ND2 1 ? 
ATOM   550  N  N   . PHE A 1 76  ? 46.177 -0.241  34.978 1.000 12.987  0 76  PHE A N   1 ? 
ATOM   551  C  CA  . PHE A 1 76  ? 45.763 0.536   33.824 1.000 12.846  0 76  PHE A CA  1 ? 
ATOM   552  C  C   . PHE A 1 76  ? 44.332 0.188   33.445 1.000 12.652  0 76  PHE A C   1 ? 
ATOM   553  O  O   . PHE A 1 76  ? 43.491 1.062   33.202 1.000 12.372  0 76  PHE A O   1 ? 
ATOM   554  C  CB  . PHE A 1 76  ? 46.714 0.348   32.649 1.000 12.947  0 76  PHE A CB  1 ? 
ATOM   555  C  CG  . PHE A 1 76  ? 46.388 1.163   31.425 1.000 13.493  0 76  PHE A CG  1 ? 
ATOM   556  C  CD1 . PHE A 1 76  ? 46.326 2.549   31.517 1.000 13.641  0 76  PHE A CD1 1 ? 
ATOM   557  C  CD2 . PHE A 1 76  ? 46.211 0.565   30.190 1.000 12.852  0 76  PHE A CD2 1 ? 
ATOM   558  C  CE1 . PHE A 1 76  ? 46.018 3.302   30.413 1.000 14.084  0 76  PHE A CE1 1 ? 
ATOM   559  C  CE2 . PHE A 1 76  ? 45.927 1.344   29.083 1.000 14.512  0 76  PHE A CE2 1 ? 
ATOM   560  C  CZ  . PHE A 1 76  ? 45.786 2.687   29.203 1.000 13.951  0 76  PHE A CZ  1 ? 
ATOM   561  N  N   . GLU A 1 77  ? 44.026 -1.115  33.360 1.000 12.112  0 77  GLU A N   1 ? 
ATOM   562  C  CA  . GLU A 1 77  ? 42.667 -1.557  33.107 1.000 13.453  0 77  GLU A CA  1 ? 
ATOM   563  C  C   . GLU A 1 77  ? 41.726 -0.947  34.142 1.000 12.451  0 77  GLU A C   1 ? 
ATOM   564  O  O   . GLU A 1 77  ? 40.612 -0.498  33.841 1.000 12.709  0 77  GLU A O   1 ? 
ATOM   565  C  CB  . GLU A 1 77  ? 42.569 -3.076  33.113 1.000 13.840  0 77  GLU A CB  1 ? 
ATOM   566  C  CG  . GLU A 1 77  ? 41.168 -3.582  32.791 1.000 16.560  0 77  GLU A CG  1 ? 
ATOM   567  C  CD  . GLU A 1 77  ? 40.946 -5.068  32.935 1.000 23.839  0 77  GLU A CD  1 ? 
ATOM   568  O  OE1 . GLU A 1 77  ? 41.934 -5.795  33.116 1.000 32.444  0 77  GLU A OE1 1 ? 
ATOM   569  O  OE2 . GLU A 1 77  ? 39.771 -5.501  32.898 1.000 25.745  0 77  GLU A OE2 1 ? 
ATOM   570  N  N   . GLN A 1 78  ? 42.107 -0.957  35.403 1.000 12.841  0 78  GLN A N   1 ? 
ATOM   571  C  CA  . GLN A 1 78  ? 41.202 -0.489  36.432 1.000 12.743  0 78  GLN A CA  1 ? 
ATOM   572  C  C   . GLN A 1 78  ? 40.859 0.992   36.260 1.000 12.979  0 78  GLN A C   1 ? 
ATOM   573  O  O   . GLN A 1 78  ? 39.687 1.384   36.478 1.000 13.018  0 78  GLN A O   1 ? 
ATOM   574  C  CB  . GLN A 1 78  ? 41.798 -0.868  37.795 1.000 14.912  0 78  GLN A CB  1 ? 
ATOM   575  C  CG  . GLN A 1 78  ? 40.880 -0.513  38.961 1.000 16.019  0 78  GLN A CG  1 ? 
ATOM   576  C  CD  . GLN A 1 78  ? 41.478 -0.828  40.314 1.000 15.922  0 78  GLN A CD  1 ? 
ATOM   577  O  OE1 . GLN A 1 78  ? 42.373 -1.667  40.457 1.000 18.595  0 78  GLN A OE1 1 ? 
ATOM   578  N  NE2 . GLN A 1 78  ? 40.947 -0.160  41.337 1.000 16.926  0 78  GLN A NE2 1 ? 
ATOM   579  N  N   . VAL A 1 79  ? 41.861 1.835   35.950 1.000 11.616  0 79  VAL A N   1 ? 
ATOM   580  C  CA  . VAL A 1 79  ? 41.611 3.252   35.735 1.000 13.352  0 79  VAL A CA  1 ? 
ATOM   581  C  C   . VAL A 1 79  ? 40.690 3.459   34.528 1.000 12.902  0 79  VAL A C   1 ? 
ATOM   582  O  O   . VAL A 1 79  ? 39.704 4.190   34.646 1.000 12.239  0 79  VAL A O   1 ? 
ATOM   583  C  CB  . VAL A 1 79  ? 42.885 4.089   35.535 1.000 15.414  0 79  VAL A CB  1 ? 
ATOM   584  C  CG1 . VAL A 1 79  ? 43.809 3.543   34.493 1.000 22.738  0 79  VAL A CG1 1 ? 
ATOM   585  C  CG2 . VAL A 1 79  ? 42.561 5.526   35.169 1.000 15.233  0 79  VAL A CG2 1 ? 
ATOM   586  N  N   . ILE A 1 80  ? 40.982 2.762   33.431 1.000 12.362  0 80  ILE A N   1 ? 
ATOM   587  C  CA  . ILE A 1 80  ? 40.253 3.021   32.196 1.000 12.206  0 80  ILE A CA  1 ? 
ATOM   588  C  C   . ILE A 1 80  ? 38.812 2.551   32.370 1.000 12.839  0 80  ILE A C   1 ? 
ATOM   589  O  O   . ILE A 1 80  ? 37.854 3.230   31.966 1.000 11.789  0 80  ILE A O   1 ? 
ATOM   590  C  CB  . ILE A 1 80  ? 40.936 2.322   31.005 1.000 12.358  0 80  ILE A CB  1 ? 
ATOM   591  C  CG1 . ILE A 1 80  ? 42.291 2.986   30.639 1.000 12.172  0 80  ILE A CG1 1 ? 
ATOM   592  C  CG2 . ILE A 1 80  ? 39.986 2.257   29.798 1.000 13.496  0 80  ILE A CG2 1 ? 
ATOM   593  C  CD1 . ILE A 1 80  ? 42.208 4.407   30.139 1.000 11.437  0 80  ILE A CD1 1 ? 
ATOM   594  N  N   . VAL A 1 81  ? 38.613 1.349   32.910 1.000 13.099  0 81  VAL A N   1 ? 
ATOM   595  C  CA  . VAL A 1 81  ? 37.252 0.853   33.082 1.000 14.549  0 81  VAL A CA  1 ? 
ATOM   596  C  C   . VAL A 1 81  ? 36.503 1.763   34.046 1.000 14.358  0 81  VAL A C   1 ? 
ATOM   597  O  O   . VAL A 1 81  ? 35.307 2.035   33.880 1.000 14.337  0 81  VAL A O   1 ? 
ATOM   598  C  CB  . VAL A 1 81  ? 37.234 -0.609  33.550 1.000 18.449  0 81  VAL A CB  1 ? 
ATOM   599  C  CG1 . VAL A 1 81  ? 35.852 -1.098  34.007 1.000 19.880  0 81  VAL A CG1 1 ? 
ATOM   600  C  CG2 . VAL A 1 81  ? 37.775 -1.497  32.440 1.000 19.868  0 81  VAL A CG2 1 ? 
ATOM   601  N  N   . GLY A 1 82  ? 37.193 2.250   35.071 1.000 14.672  0 82  GLY A N   1 ? 
ATOM   602  C  CA  . GLY A 1 82  ? 36.574 3.172   36.002 1.000 14.234  0 82  GLY A CA  1 ? 
ATOM   603  C  C   . GLY A 1 82  ? 36.153 4.479   35.334 1.000 12.243  0 82  GLY A C   1 ? 
ATOM   604  O  O   . GLY A 1 82  ? 35.023 4.948   35.569 1.000 13.786  0 82  GLY A O   1 ? 
ATOM   605  N  N   . MET A 1 83  ? 37.005 5.025   34.463 1.000 11.676  0 83  MET A N   1 ? 
ATOM   606  C  CA  . MET A 1 83  ? 36.682 6.197   33.661 1.000 11.261  0 83  MET A CA  1 ? 
ATOM   607  C  C   . MET A 1 83  ? 35.441 5.976   32.812 1.000 12.140  0 83  MET A C   1 ? 
ATOM   608  O  O   . MET A 1 83  ? 34.633 6.876   32.604 1.000 12.533  0 83  MET A O   1 ? 
ATOM   609  C  CB  . MET A 1 83  ? 37.863 6.556   32.777 1.000 11.697  0 83  MET A CB  1 ? 
ATOM   610  C  CG  . MET A 1 83  ? 38.966 7.166   33.579 1.000 12.690  0 83  MET A CG  1 ? 
ATOM   611  S  SD  . MET A 1 83  ? 40.521 7.290   32.686 1.000 14.363  0 83  MET A SD  1 ? 
ATOM   612  C  CE  . MET A 1 83  ? 39.965 8.403   31.393 1.000 16.543  0 83  MET A CE  1 ? 
ATOM   613  N  N   . MET A 1 84  ? 35.287 4.744   32.315 1.000 11.145  0 84  MET A N   1 ? 
ATOM   614  C  CA  . MET A 1 84  ? 34.178 4.440   31.444 1.000 11.085  0 84  MET A CA  1 ? 
ATOM   615  C  C   . MET A 1 84  ? 32.856 4.216   32.149 1.000 13.201  0 84  MET A C   1 ? 
ATOM   616  O  O   . MET A 1 84  ? 31.809 4.118   31.488 1.000 13.170  0 84  MET A O   1 ? 
ATOM   617  C  CB  . MET A 1 84  ? 34.445 3.157   30.681 1.000 11.582  0 84  MET A CB  1 ? 
ATOM   618  C  CG  . MET A 1 84  ? 35.534 3.248   29.642 1.000 11.786  0 84  MET A CG  1 ? 
ATOM   619  S  SD  . MET A 1 84  ? 35.319 4.504   28.376 1.000 14.124  0 84  MET A SD  1 ? 
ATOM   620  C  CE  . MET A 1 84  ? 33.673 4.083   27.792 1.000 15.297  0 84  MET A CE  1 ? 
ATOM   621  N  N   . THR A 1 85  ? 32.898 4.097   33.471 1.000 13.239  0 85  THR A N   1 ? 
ATOM   622  C  CA  . THR A 1 85  ? 31.713 3.766   34.260 1.000 13.814  0 85  THR A CA  1 ? 
ATOM   623  C  C   . THR A 1 85  ? 30.936 5.034   34.585 1.000 12.643  0 85  THR A C   1 ? 
ATOM   624  O  O   . THR A 1 85  ? 31.479 6.038   35.045 1.000 12.680  0 85  THR A O   1 ? 
ATOM   625  C  CB  . THR A 1 85  ? 32.138 3.016   35.528 1.000 12.823  0 85  THR A CB  1 ? 
ATOM   626  O  OG1 . THR A 1 85  ? 32.909 1.873   35.130 1.000 15.081  0 85  THR A OG1 1 ? 
ATOM   627  C  CG2 . THR A 1 85  ? 30.954 2.637   36.397 1.000 13.222  0 85  THR A CG2 1 ? 
ATOM   628  N  N   . PRO A 1 86  ? 29.590 5.071   34.403 1.000 13.943  0 86  PRO A N   1 ? 
ATOM   629  C  CA  . PRO A 1 86  ? 28.816 6.208   34.877 1.000 14.097  0 86  PRO A CA  1 ? 
ATOM   630  C  C   . PRO A 1 86  ? 29.144 6.596   36.315 1.000 13.022  0 86  PRO A C   1 ? 
ATOM   631  O  O   . PRO A 1 86  ? 29.347 5.745   37.158 1.000 13.790  0 86  PRO A O   1 ? 
ATOM   632  C  CB  . PRO A 1 86  ? 27.349 5.728   34.685 1.000 16.298  0 86  PRO A CB  1 ? 
ATOM   633  C  CG  . PRO A 1 86  ? 27.439 4.664   33.599 1.000 16.570  0 86  PRO A CG  1 ? 
ATOM   634  C  CD  . PRO A 1 86  ? 28.770 3.999   33.815 1.000 13.767  0 86  PRO A CD  1 ? 
ATOM   635  N  N   . THR A 1 87  ? 29.040 7.883   36.603 1.000 14.112  0 87  THR A N   1 ? 
ATOM   636  C  CA  . THR A 1 87  ? 29.487 8.457   37.852 1.000 14.343  0 87  THR A CA  1 ? 
ATOM   637  C  C   . THR A 1 87  ? 28.880 7.737   39.045 1.000 14.548  0 87  THR A C   1 ? 
ATOM   638  O  O   . THR A 1 87  ? 29.593 7.359   39.973 1.000 14.836  0 87  THR A O   1 ? 
ATOM   639  C  CB  . THR A 1 87  ? 29.157 9.959   37.865 1.000 17.329  0 87  THR A CB  1 ? 
ATOM   640  O  OG1 . THR A 1 87  ? 29.798 10.591  36.767 1.000 19.741  0 87  THR A OG1 1 ? 
ATOM   641  C  CG2 . THR A 1 87  ? 29.669 10.669  39.097 1.000 19.900  0 87  THR A CG2 1 ? 
ATOM   642  N  N   . VAL A 1 88  ? 27.537 7.672   39.097 1.000 13.110  0 88  VAL A N   1 ? 
ATOM   643  C  CA  . VAL A 1 88  ? 26.902 7.109   40.288 1.000 13.488  0 88  VAL A CA  1 ? 
ATOM   644  C  C   . VAL A 1 88  ? 27.234 5.624   40.394 1.000 13.230  0 88  VAL A C   1 ? 
ATOM   645  O  O   . VAL A 1 88  ? 27.518 5.105   41.484 1.000 13.557  0 88  VAL A O   1 ? 
ATOM   646  C  CB  . VAL A 1 88  ? 25.378 7.316   40.240 1.000 15.089  0 88  VAL A CB  1 ? 
ATOM   647  C  CG1 . VAL A 1 88  ? 24.671 6.626   41.397 1.000 16.242  0 88  VAL A CG1 1 ? 
ATOM   648  C  CG2 . VAL A 1 88  ? 25.064 8.790   40.262 1.000 17.428  0 88  VAL A CG2 1 ? 
ATOM   649  N  N   . LEU A 1 89  ? 27.172 4.889   39.276 1.000 12.784  0 89  LEU A N   1 ? 
ATOM   650  C  CA  . LEU A 1 89  ? 27.445 3.470   39.288 1.000 13.433  0 89  LEU A CA  1 ? 
ATOM   651  C  C   . LEU A 1 89  ? 28.874 3.191   39.772 1.000 12.819  0 89  LEU A C   1 ? 
ATOM   652  O  O   . LEU A 1 89  ? 29.130 2.169   40.412 1.000 12.339  0 89  LEU A O   1 ? 
ATOM   653  C  CB  . LEU A 1 89  ? 27.175 2.874   37.913 1.000 13.489  0 89  LEU A CB  1 ? 
ATOM   654  C  CG  . LEU A 1 89  ? 27.315 1.347   37.784 1.000 15.554  0 89  LEU A CG  1 ? 
ATOM   655  C  CD1 . LEU A 1 89  ? 26.396 0.558   38.717 1.000 16.639  0 89  LEU A CD1 1 ? 
ATOM   656  C  CD2 . LEU A 1 89  ? 27.114 0.894   36.343 1.000 16.393  0 89  LEU A CD2 1 ? 
ATOM   657  N  N   . TYR A 1 90  ? 29.816 4.081   39.429 1.000 12.770  0 90  TYR A N   1 ? 
ATOM   658  C  CA  . TYR A 1 90  ? 31.203 3.850   39.832 1.000 11.509  0 90  TYR A CA  1 ? 
ATOM   659  C  C   . TYR A 1 90  ? 31.297 3.861   41.352 1.000 12.658  0 90  TYR A C   1 ? 
ATOM   660  O  O   . TYR A 1 90  ? 31.946 2.991   41.952 1.000 12.644  0 90  TYR A O   1 ? 
ATOM   661  C  CB  . TYR A 1 90  ? 32.117 4.926   39.225 1.000 13.181  0 90  TYR A CB  1 ? 
ATOM   662  C  CG  . TYR A 1 90  ? 33.585 4.705   39.588 1.000 12.869  0 90  TYR A CG  1 ? 
ATOM   663  C  CD1 . TYR A 1 90  ? 34.287 3.598   39.167 1.000 13.398  0 90  TYR A CD1 1 ? 
ATOM   664  C  CD2 . TYR A 1 90  ? 34.275 5.660   40.336 1.000 13.785  0 90  TYR A CD2 1 ? 
ATOM   665  C  CE1 . TYR A 1 90  ? 35.606 3.361   39.552 1.000 12.797  0 90  TYR A CE1 1 ? 
ATOM   666  C  CE2 . TYR A 1 90  ? 35.595 5.454   40.706 1.000 13.907  0 90  TYR A CE2 1 ? 
ATOM   667  C  CZ  . TYR A 1 90  ? 36.261 4.306   40.310 1.000 14.766  0 90  TYR A CZ  1 ? 
ATOM   668  O  OH  . TYR A 1 90  ? 37.589 4.097   40.642 1.000 14.694  0 90  TYR A OH  1 ? 
ATOM   669  N  N   . ASP A 1 91  ? 30.614 4.814   42.008 1.000 12.627  0 91  ASP A N   1 ? 
ATOM   670  C  CA  . ASP A 1 91  ? 30.579 4.868   43.467 1.000 12.136  0 91  ASP A CA  1 ? 
ATOM   671  C  C   . ASP A 1 91  ? 29.916 3.608   43.998 1.000 12.726  0 91  ASP A C   1 ? 
ATOM   672  O  O   . ASP A 1 91  ? 30.362 3.032   44.983 1.000 12.287  0 91  ASP A O   1 ? 
ATOM   673  C  CB  . ASP A 1 91  ? 29.907 6.140   43.968 1.000 14.860  0 91  ASP A CB  1 ? 
ATOM   674  C  CG  . ASP A 1 91  ? 30.692 7.430   43.783 1.000 16.816  0 91  ASP A CG  1 ? 
ATOM   675  O  OD1 . ASP A 1 91  ? 31.880 7.320   43.396 1.000 15.867  0 91  ASP A OD1 1 ? 
ATOM   676  O  OD2 . ASP A 1 91  ? 30.103 8.479   44.132 1.000 18.951  0 91  ASP A OD2 1 ? 
ATOM   677  N  N   . VAL A 1 92  ? 28.786 3.223   43.392 1.000 13.019  0 92  VAL A N   1 ? 
ATOM   678  C  CA  . VAL A 1 92  ? 28.046 2.034   43.809 1.000 13.071  0 92  VAL A CA  1 ? 
ATOM   679  C  C   . VAL A 1 92  ? 28.931 0.797   43.777 1.000 13.397  0 92  VAL A C   1 ? 
ATOM   680  O  O   . VAL A 1 92  ? 28.945 -0.026  44.711 1.000 14.331  0 92  VAL A O   1 ? 
ATOM   681  C  CB  . VAL A 1 92  ? 26.810 1.855   42.906 1.000 13.678  0 92  VAL A CB  1 ? 
ATOM   682  C  CG1 . VAL A 1 92  ? 26.234 0.455   43.055 1.000 14.113  0 92  VAL A CG1 1 ? 
ATOM   683  C  CG2 . VAL A 1 92  ? 25.734 2.884   43.205 1.000 14.187  0 92  VAL A CG2 1 ? 
ATOM   684  N  N   . GLN A 1 93  ? 29.630 0.622   42.663 1.000 13.627  0 93  GLN A N   1 ? 
ATOM   685  C  CA  . GLN A 1 93  ? 30.522 -0.515  42.459 1.000 14.225  0 93  GLN A CA  1 ? 
ATOM   686  C  C   . GLN A 1 93  ? 31.686 -0.470  43.451 1.000 12.321  0 93  GLN A C   1 ? 
ATOM   687  O  O   . GLN A 1 93  ? 32.147 -1.530  43.893 1.000 14.647  0 93  GLN A O   1 ? 
ATOM   688  C  CB  . GLN A 1 93  ? 30.993 -0.555  41.003 1.000 15.874  0 93  GLN A CB  1 ? 
ATOM   689  C  CG  . GLN A 1 93  ? 29.841 -0.913  40.063 1.000 17.723  0 93  GLN A CG  1 ? 
ATOM   690  C  CD  . GLN A 1 93  ? 30.226 -1.134  38.621 1.000 23.027  0 93  GLN A CD  1 ? 
ATOM   691  O  OE1 . GLN A 1 93  ? 31.253 -0.647  38.163 1.000 25.344  0 93  GLN A OE1 1 ? 
ATOM   692  N  NE2 . GLN A 1 93  ? 29.358 -1.832  37.898 1.000 25.951  0 93  GLN A NE2 1 ? 
ATOM   693  N  N   . GLU A 1 94  ? 32.189 0.727   43.778 1.000 12.807  0 94  GLU A N   1 ? 
ATOM   694  C  CA  . GLU A 1 94  ? 33.283 0.807   44.743 1.000 12.415  0 94  GLU A CA  1 ? 
ATOM   695  C  C   . GLU A 1 94  ? 32.794 0.396   46.121 1.000 12.873  0 94  GLU A C   1 ? 
ATOM   696  O  O   . GLU A 1 94  ? 33.474 -0.340  46.835 1.000 13.610  0 94  GLU A O   1 ? 
ATOM   697  C  CB  . GLU A 1 94  ? 33.897 2.203   44.743 1.000 13.470  0 94  GLU A CB  1 ? 
ATOM   698  C  CG  . GLU A 1 94  ? 34.769 2.445   43.516 1.000 16.588  0 94  GLU A CG  1 ? 
ATOM   699  C  CD  . GLU A 1 94  ? 36.013 1.593   43.546 1.000 20.064  0 94  GLU A CD  1 ? 
ATOM   700  O  OE1 . GLU A 1 94  ? 36.809 1.774   44.495 1.000 18.848  0 94  GLU A OE1 1 ? 
ATOM   701  O  OE2 . GLU A 1 94  ? 36.133 0.667   42.702 1.000 24.454  0 94  GLU A OE2 1 ? 
ATOM   702  N  N   . LEU A 1 95  ? 31.592 0.829   46.497 1.000 12.534  0 95  LEU A N   1 ? 
ATOM   703  C  CA  . LEU A 1 95  ? 31.052 0.410   47.773 1.000 12.926  0 95  LEU A CA  1 ? 
ATOM   704  C  C   . LEU A 1 95  ? 30.863 -1.111  47.802 1.000 13.706  0 95  LEU A C   1 ? 
ATOM   705  O  O   . LEU A 1 95  ? 31.150 -1.742  48.821 1.000 15.628  0 95  LEU A O   1 ? 
ATOM   706  C  CB  . LEU A 1 95  ? 29.730 1.126   48.080 1.000 13.616  0 95  LEU A CB  1 ? 
ATOM   707  C  CG  . LEU A 1 95  ? 29.845 2.622   48.401 1.000 13.511  0 95  LEU A CG  1 ? 
ATOM   708  C  CD1 . LEU A 1 95  ? 28.501 3.288   48.345 1.000 14.699  0 95  LEU A CD1 1 ? 
ATOM   709  C  CD2 . LEU A 1 95  ? 30.489 2.917   49.748 1.000 14.893  0 95  LEU A CD2 1 ? 
ATOM   710  N  N   . ARG A 1 96  ? 30.323 -1.697  46.739 1.000 13.858  0 96  ARG A N   1 ? 
ATOM   711  C  CA  . ARG A 1 96  ? 30.072 -3.132  46.739 1.000 15.865  0 96  ARG A CA  1 ? 
ATOM   712  C  C   . ARG A 1 96  ? 31.387 -3.882  46.875 1.000 17.264  0 96  ARG A C   1 ? 
ATOM   713  O  O   . ARG A 1 96  ? 31.460 -4.834  47.656 1.000 18.105  0 96  ARG A O   1 ? 
ATOM   714  C  CB  . ARG A 1 96  ? 29.297 -3.525  45.479 1.000 17.014  0 96  ARG A CB  1 ? 
ATOM   715  C  CG  . ARG A 1 96  ? 28.911 -5.006  45.414 1.000 22.221  0 96  ARG A CG  1 ? 
ATOM   716  C  CD  . ARG A 1 96  ? 27.650 -5.330  46.189 1.000 26.541  0 96  ARG A CD  1 ? 
ATOM   717  N  NE  . ARG A 1 96  ? 27.610 -6.701  46.689 1.000 35.802  0 96  ARG A NE  1 ? 
ATOM   718  C  CZ  . ARG A 1 96  ? 27.904 -7.100  47.934 1.000 36.080  0 96  ARG A CZ  1 ? 
ATOM   719  N  NH1 . ARG A 1 96  ? 27.980 -6.272  48.975 1.000 31.978  0 96  ARG A NH1 1 ? 
ATOM   720  N  NH2 . ARG A 1 96  ? 28.053 -8.386  48.127 1.000 37.958  0 96  ARG A NH2 1 ? 
ATOM   721  N  N   . ARG A 1 97  ? 32.418 -3.430  46.175 1.000 15.597  0 97  ARG A N   1 ? 
ATOM   722  C  CA  . ARG A 1 97  ? 33.707 -4.113  46.208 1.000 17.112  0 97  ARG A CA  1 ? 
ATOM   723  C  C   . ARG A 1 97  ? 34.297 -4.011  47.608 1.000 17.113  0 97  ARG A C   1 ? 
ATOM   724  O  O   . ARG A 1 97  ? 34.916 -4.989  48.093 1.000 17.596  0 97  ARG A O   1 ? 
ATOM   725  C  CB  . ARG A 1 97  ? 34.528 -3.461  45.107 1.000 20.914  0 97  ARG A CB  1 ? 
ATOM   726  C  CG  . ARG A 1 97  ? 35.905 -4.054  44.926 1.000 27.994  0 97  ARG A CG  1 ? 
ATOM   727  C  CD  . ARG A 1 97  ? 36.369 -3.422  43.630 1.000 31.959  0 97  ARG A CD  1 ? 
ATOM   728  N  NE  . ARG A 1 97  ? 37.804 -3.641  43.555 1.000 39.176  0 97  ARG A NE  1 ? 
ATOM   729  C  CZ  . ARG A 1 97  ? 38.750 -2.728  43.470 1.000 39.638  0 97  ARG A CZ  1 ? 
ATOM   730  N  NH1 . ARG A 1 97  ? 38.463 -1.435  43.581 1.000 38.109  0 97  ARG A NH1 1 ? 
ATOM   731  N  NH2 . ARG A 1 97  ? 39.980 -3.154  43.261 1.000 38.317  0 97  ARG A NH2 1 ? 
ATOM   732  N  N   . ALA A 1 98  ? 34.026 -2.890  48.283 1.000 16.250  0 98  ALA A N   1 ? 
ATOM   733  C  CA  . ALA A 1 98  ? 34.523 -2.691  49.628 1.000 16.962  0 98  ALA A CA  1 ? 
ATOM   734  C  C   . ALA A 1 98  ? 33.892 -3.684  50.621 1.000 18.522  0 98  ALA A C   1 ? 
ATOM   735  O  O   . ALA A 1 98  ? 34.535 -4.017  51.614 1.000 20.769  0 98  ALA A O   1 ? 
ATOM   736  C  CB  . ALA A 1 98  ? 34.335 -1.236  50.033 1.000 17.698  0 98  ALA A CB  1 ? 
ATOM   737  N  N   . MET A 1 99  ? 32.691 -4.215  50.342 1.000 17.646  0 99  MET A N   1 ? 
ATOM   738  C  CA  . MET A 1 99  ? 31.964 -5.036  51.291 1.000 20.547  0 99  MET A CA  1 ? 
ATOM   739  C  C   . MET A 1 99  ? 31.847 -6.494  50.870 1.000 26.242  0 99  MET A C   1 ? 
ATOM   740  O  O   . MET A 1 99  ? 31.340 -7.277  51.665 1.000 27.387  0 99  MET A O   1 ? 
ATOM   741  C  CB  . MET A 1 99  ? 30.555 -4.482  51.497 1.000 20.758  0 99  MET A CB  1 ? 
ATOM   742  C  CG  . MET A 1 99  ? 30.637 -3.243  52.360 1.000 18.650  0 99  MET A CG  1 ? 
ATOM   743  S  SD  . MET A 1 99  ? 29.086 -2.456  52.785 1.000 21.278  0 99  MET A SD  1 ? 
ATOM   744  C  CE  . MET A 1 99  ? 28.724 -1.719  51.178 1.000 17.701  0 99  MET A CE  1 ? 
ATOM   745  N  N   . LYS A 1 100 ? 32.259 -6.845  49.653 1.000 29.510  0 100 LYS A N   1 ? 
ATOM   746  C  CA  . LYS A 1 100 ? 31.923 -8.178  49.167 1.000 39.217  0 100 LYS A CA  1 ? 
ATOM   747  C  C   . LYS A 1 100 ? 32.986 -9.168  49.651 1.000 45.222  0 100 LYS A C   1 ? 
ATOM   748  O  O   . LYS A 1 100 ? 34.151 -8.799  49.787 1.000 46.093  0 100 LYS A O   1 ? 
ATOM   749  C  CB  . LYS A 1 100 ? 31.640 -8.207  47.662 1.000 42.425  0 100 LYS A CB  1 ? 
ATOM   750  C  CG  . LYS A 1 100 ? 32.793 -8.217  46.668 1.000 46.611  0 100 LYS A CG  1 ? 
ATOM   751  C  CD  . LYS A 1 100 ? 32.346 -8.742  45.297 1.000 47.699  0 100 LYS A CD  1 ? 
ATOM   752  C  CE  . LYS A 1 100 ? 31.378 -7.866  44.506 1.000 45.418  0 100 LYS A CE  1 ? 
ATOM   753  N  NZ  . LYS A 1 100 ? 31.978 -6.621  43.977 1.000 39.164  0 100 LYS A NZ  1 ? 
ATOM   754  N  N   . GLY A 1 101 ? 32.543 -10.409 49.930 1.000 48.496  0 101 GLY A N   1 ? 
ATOM   755  C  CA  . GLY A 1 101 ? 33.342 -11.410 50.620 1.000 52.882  0 101 GLY A CA  1 ? 
ATOM   756  C  C   . GLY A 1 101 ? 33.530 -11.039 52.088 1.000 58.023  0 101 GLY A C   1 ? 
ATOM   757  O  O   . GLY A 1 101 ? 33.159 -9.941  52.500 1.000 63.464  0 101 GLY A O   1 ? 
ATOM   758  N  N   . ALA A 1 102 ? 34.093 -11.967 52.877 1.000 59.732  0 102 ALA A N   1 ? 
ATOM   759  C  CA  . ALA A 1 102 ? 34.608 -11.627 54.196 1.000 58.488  0 102 ALA A CA  1 ? 
ATOM   760  C  C   . ALA A 1 102 ? 35.802 -10.682 54.031 1.000 53.614  0 102 ALA A C   1 ? 
ATOM   761  O  O   . ALA A 1 102 ? 36.530 -10.761 53.044 1.000 65.171  0 102 ALA A O   1 ? 
ATOM   762  C  CB  . ALA A 1 102 ? 34.967 -12.886 54.962 1.000 58.877  0 102 ALA A CB  1 ? 
ATOM   763  N  N   . GLY A 1 103 ? 35.983 -9.771  54.992 1.000 47.437  0 103 GLY A N   1 ? 
ATOM   764  C  CA  . GLY A 1 103 ? 36.924 -8.663  54.851 1.000 43.528  0 103 GLY A CA  1 ? 
ATOM   765  C  C   . GLY A 1 103 ? 36.206 -7.417  54.319 1.000 41.528  0 103 GLY A C   1 ? 
ATOM   766  O  O   . GLY A 1 103 ? 35.279 -7.544  53.507 1.000 41.269  0 103 GLY A O   1 ? 
ATOM   767  N  N   . THR A 1 104 ? 36.595 -6.229  54.820 1.000 30.757  0 104 THR A N   1 ? 
ATOM   768  C  CA  . THR A 1 104 ? 35.867 -4.998  54.532 1.000 27.936  0 104 THR A CA  1 ? 
ATOM   769  C  C   . THR A 1 104 ? 36.876 -3.869  54.340 1.000 26.961  0 104 THR A C   1 ? 
ATOM   770  O  O   . THR A 1 104 ? 37.694 -3.627  55.214 1.000 27.991  0 104 THR A O   1 ? 
ATOM   771  C  CB  . THR A 1 104 ? 34.859 -4.656  55.642 1.000 27.376  0 104 THR A CB  1 ? 
ATOM   772  O  OG1 . THR A 1 104 ? 33.889 -5.707  55.684 1.000 31.169  0 104 THR A OG1 1 ? 
ATOM   773  C  CG2 . THR A 1 104 ? 34.061 -3.392  55.368 1.000 29.789  0 104 THR A CG2 1 ? 
ATOM   774  N  N   . ASP A 1 105 ? 36.759 -3.126  53.230 1.000 22.922  0 105 ASP A N   1 ? 
ATOM   775  C  CA  . ASP A 1 105 ? 37.599 -1.960  52.995 1.000 20.320  0 105 ASP A CA  1 ? 
ATOM   776  C  C   . ASP A 1 105 ? 36.955 -0.746  53.667 1.000 19.470  0 105 ASP A C   1 ? 
ATOM   777  O  O   . ASP A 1 105 ? 36.234 0.005   53.027 1.000 17.358  0 105 ASP A O   1 ? 
ATOM   778  C  CB  . ASP A 1 105 ? 37.828 -1.708  51.515 1.000 18.547  0 105 ASP A CB  1 ? 
ATOM   779  C  CG  . ASP A 1 105 ? 38.721 -0.537  51.165 1.000 20.278  0 105 ASP A CG  1 ? 
ATOM   780  O  OD1 . ASP A 1 105 ? 39.051 0.250   52.078 1.000 20.548  0 105 ASP A OD1 1 ? 
ATOM   781  O  OD2 . ASP A 1 105 ? 39.082 -0.381  49.969 1.000 22.152  0 105 ASP A OD2 1 ? 
ATOM   782  N  N   . GLU A 1 106 ? 37.228 -0.582  54.964 1.000 19.912  0 106 GLU A N   1 ? 
ATOM   783  C  CA  . GLU A 1 106 ? 36.609 0.454   55.775 1.000 20.348  0 106 GLU A CA  1 ? 
ATOM   784  C  C   . GLU A 1 106 ? 37.008 1.851   55.298 1.000 19.143  0 106 GLU A C   1 ? 
ATOM   785  O  O   . GLU A 1 106 ? 36.184 2.762   55.389 1.000 18.148  0 106 GLU A O   1 ? 
ATOM   786  C  CB  . GLU A 1 106 ? 36.890 0.246   57.266 1.000 24.658  0 106 GLU A CB  1 ? 
ATOM   787  C  CG  . GLU A 1 106 ? 36.186 -1.022  57.754 1.000 26.279  0 106 GLU A CG  1 ? 
ATOM   788  C  CD  . GLU A 1 106 ? 36.191 -1.290  59.250 1.000 32.542  0 106 GLU A CD  1 ? 
ATOM   789  O  OE1 . GLU A 1 106 ? 37.086 -0.720  59.900 1.000 32.341  0 106 GLU A OE1 1 ? 
ATOM   790  O  OE2 . GLU A 1 106 ? 35.296 -2.028  59.752 1.000 34.086  0 106 GLU A OE2 1 ? 
ATOM   791  N  N   . GLY A 1 107 ? 38.232 2.019   54.780 1.000 18.284  0 107 GLY A N   1 ? 
ATOM   792  C  CA  . GLY A 1 107 ? 38.687 3.319   54.299 1.000 15.737  0 107 GLY A CA  1 ? 
ATOM   793  C  C   . GLY A 1 107 ? 37.849 3.799   53.119 1.000 16.125  0 107 GLY A C   1 ? 
ATOM   794  O  O   . GLY A 1 107 ? 37.502 4.963   53.041 1.000 17.527  0 107 GLY A O   1 ? 
ATOM   795  N  N   . CYS A 1 108 ? 37.480 2.881   52.214 1.000 16.233  0 108 CYS A N   1 ? 
ATOM   796  C  CA  . CYS A 1 108 ? 36.637 3.237   51.079 1.000 14.506  0 108 CYS A CA  1 ? 
ATOM   797  C  C   . CYS A 1 108 ? 35.243 3.697   51.535 1.000 13.314  0 108 CYS A C   1 ? 
ATOM   798  O  O   . CYS A 1 108 ? 34.719 4.720   51.064 1.000 13.637  0 108 CYS A O   1 ? 
ATOM   799  C  CB  . CYS A 1 108 ? 36.528 2.075   50.100 1.000 16.189  0 108 CYS A CB  1 ? 
ATOM   800  S  SG  . CYS A 1 108 ? 35.365 2.364   48.754 1.000 17.273  0 108 CYS A SG  1 ? 
ATOM   801  N  N   . LEU A 1 109 ? 34.652 2.954   52.479 1.000 14.524  0 109 LEU A N   1 ? 
ATOM   802  C  CA  . LEU A 1 109 ? 33.340 3.307   53.011 1.000 14.464  0 109 LEU A CA  1 ? 
ATOM   803  C  C   . LEU A 1 109 ? 33.330 4.715   53.613 1.000 13.171  0 109 LEU A C   1 ? 
ATOM   804  O  O   . LEU A 1 109 ? 32.453 5.496   53.312 1.000 13.859  0 109 LEU A O   1 ? 
ATOM   805  C  CB  . LEU A 1 109 ? 32.864 2.294   54.043 1.000 15.206  0 109 LEU A CB  1 ? 
ATOM   806  C  CG  . LEU A 1 109 ? 32.747 0.837   53.570 1.000 16.270  0 109 LEU A CG  1 ? 
ATOM   807  C  CD1 . LEU A 1 109 ? 32.131 0.002   54.698 1.000 16.595  0 109 LEU A CD1 1 ? 
ATOM   808  C  CD2 . LEU A 1 109 ? 31.888 0.668   52.332 1.000 16.839  0 109 LEU A CD2 1 ? 
ATOM   809  N  N   . ILE A 1 110 ? 34.342 5.031   54.442 1.000 15.256  0 110 ILE A N   1 ? 
ATOM   810  C  CA  . ILE A 1 110 ? 34.463 6.335   55.068 1.000 14.680  0 110 ILE A CA  1 ? 
ATOM   811  C  C   . ILE A 1 110 ? 34.571 7.409   53.990 1.000 14.048  0 110 ILE A C   1 ? 
ATOM   812  O  O   . ILE A 1 110 ? 33.871 8.417   54.045 1.000 13.501  0 110 ILE A O   1 ? 
ATOM   813  C  CB  . ILE A 1 110 ? 35.693 6.358   55.999 1.000 14.983  0 110 ILE A CB  1 ? 
ATOM   814  C  CG1 . ILE A 1 110 ? 35.476 5.519   57.231 1.000 14.803  0 110 ILE A CG1 1 ? 
ATOM   815  C  CG2 . ILE A 1 110 ? 36.038 7.797   56.369 1.000 15.605  0 110 ILE A CG2 1 ? 
ATOM   816  C  CD1 . ILE A 1 110 ? 36.734 5.288   58.028 1.000 15.920  0 110 ILE A CD1 1 ? 
ATOM   817  N  N   . GLU A 1 111 ? 35.482 7.187   53.032 1.000 12.458  0 111 GLU A N   1 ? 
ATOM   818  C  CA  . GLU A 1 111 ? 35.795 8.193   52.024 1.000 14.236  0 111 GLU A CA  1 ? 
ATOM   819  C  C   . GLU A 1 111 ? 34.559 8.582   51.216 1.000 14.544  0 111 GLU A C   1 ? 
ATOM   820  O  O   . GLU A 1 111 ? 34.320 9.762   50.974 1.000 14.584  0 111 GLU A O   1 ? 
ATOM   821  C  CB  . GLU A 1 111 ? 36.900 7.640   51.127 1.000 15.373  0 111 GLU A CB  1 ? 
ATOM   822  C  CG  . GLU A 1 111 ? 37.329 8.604   50.019 1.000 18.496  0 111 GLU A CG  1 ? 
ATOM   823  C  CD  . GLU A 1 111 ? 38.080 7.825   48.962 1.000 21.525  0 111 GLU A CD  1 ? 
ATOM   824  O  OE1 . GLU A 1 111 ? 39.024 7.055   49.297 1.000 23.990  0 111 GLU A OE1 1 ? 
ATOM   825  O  OE2 . GLU A 1 111 ? 37.646 7.904   47.785 1.000 20.249  0 111 GLU A OE2 1 ? 
ATOM   826  N  N   . ILE A 1 112 ? 33.806 7.596   50.723 1.000 13.314  0 112 ILE A N   1 ? 
ATOM   827  C  CA  . ILE A 1 112 ? 32.646 7.892   49.908 1.000 14.216  0 112 ILE A CA  1 ? 
ATOM   828  C  C   . ILE A 1 112 ? 31.519 8.449   50.793 1.000 12.513  0 112 ILE A C   1 ? 
ATOM   829  O  O   . ILE A 1 112 ? 30.923 9.453   50.486 1.000 14.198  0 112 ILE A O   1 ? 
ATOM   830  C  CB  . ILE A 1 112 ? 32.233 6.652   49.090 1.000 13.294  0 112 ILE A CB  1 ? 
ATOM   831  C  CG1 . ILE A 1 112 ? 33.276 6.278   48.015 1.000 13.995  0 112 ILE A CG1 1 ? 
ATOM   832  C  CG2 . ILE A 1 112 ? 30.846 6.854   48.451 1.000 13.790  0 112 ILE A CG2 1 ? 
ATOM   833  C  CD1 . ILE A 1 112 ? 32.982 4.942   47.367 1.000 14.485  0 112 ILE A CD1 1 ? 
ATOM   834  N  N   . LEU A 1 113 ? 31.259 7.848   51.940 1.000 13.215  0 113 LEU A N   1 ? 
ATOM   835  C  CA  . LEU A 1 113 ? 30.103 8.247   52.727 1.000 14.637  0 113 LEU A CA  1 ? 
ATOM   836  C  C   . LEU A 1 113 ? 30.286 9.593   53.407 1.000 14.712  0 113 LEU A C   1 ? 
ATOM   837  O  O   . LEU A 1 113 ? 29.279 10.255  53.690 1.000 15.787  0 113 LEU A O   1 ? 
ATOM   838  C  CB  . LEU A 1 113 ? 29.712 7.154   53.703 1.000 15.983  0 113 LEU A CB  1 ? 
ATOM   839  C  CG  . LEU A 1 113 ? 29.157 5.906   53.014 1.000 17.601  0 113 LEU A CG  1 ? 
ATOM   840  C  CD1 . LEU A 1 113 ? 29.072 4.795   54.065 1.000 18.643  0 113 LEU A CD1 1 ? 
ATOM   841  C  CD2 . LEU A 1 113 ? 27.840 6.129   52.287 1.000 19.683  0 113 LEU A CD2 1 ? 
ATOM   842  N  N   . ALA A 1 114 ? 31.538 9.985   53.719 1.000 14.601  0 114 ALA A N   1 ? 
ATOM   843  C  CA  . ALA A 1 114 ? 31.744 11.299  54.316 1.000 14.650  0 114 ALA A CA  1 ? 
ATOM   844  C  C   . ALA A 1 114 ? 31.856 12.413  53.280 1.000 15.386  0 114 ALA A C   1 ? 
ATOM   845  O  O   . ALA A 1 114 ? 31.609 13.574  53.640 1.000 15.762  0 114 ALA A O   1 ? 
ATOM   846  C  CB  . ALA A 1 114 ? 32.982 11.296  55.178 1.000 17.029  0 114 ALA A CB  1 ? 
ATOM   847  N  N   . SER A 1 115 ? 32.267 12.107  52.035 1.000 13.986  0 115 SER A N   1 ? 
ATOM   848  C  CA  . SER A 1 115 ? 32.577 13.146  51.062 1.000 12.488  0 115 SER A CA  1 ? 
ATOM   849  C  C   . SER A 1 115 ? 31.422 13.430  50.110 1.000 14.069  0 115 SER A C   1 ? 
ATOM   850  O  O   . SER A 1 115 ? 31.399 14.483  49.469 1.000 15.939  0 115 SER A O   1 ? 
ATOM   851  C  CB  . SER A 1 115 ? 33.833 12.803  50.274 1.000 12.896  0 115 SER A CB  1 ? 
ATOM   852  O  OG  . SER A 1 115 ? 33.614 11.728  49.376 1.000 13.598  0 115 SER A OG  1 ? 
ATOM   853  N  N   . ARG A 1 116 ? 30.521 12.486  49.923 1.000 13.785  0 116 ARG A N   1 ? 
ATOM   854  C  CA  . ARG A 1 116 ? 29.377 12.743  49.060 1.000 14.432  0 116 ARG A CA  1 ? 
ATOM   855  C  C   . ARG A 1 116 ? 28.313 13.545  49.824 1.000 14.329  0 116 ARG A C   1 ? 
ATOM   856  O  O   . ARG A 1 116 ? 28.128 13.417  51.027 1.000 17.621  0 116 ARG A O   1 ? 
ATOM   857  C  CB  . ARG A 1 116 ? 28.859 11.398  48.514 1.000 14.916  0 116 ARG A CB  1 ? 
ATOM   858  C  CG  . ARG A 1 116 ? 29.542 10.863  47.269 1.000 17.400  0 116 ARG A CG  1 ? 
ATOM   859  C  CD  . ARG A 1 116 ? 30.978 10.800  47.243 1.000 20.558  0 116 ARG A CD  1 ? 
ATOM   860  N  NE  . ARG A 1 116 ? 31.516 10.173  46.030 1.000 18.750  0 116 ARG A NE  1 ? 
ATOM   861  C  CZ  . ARG A 1 116 ? 32.790 9.932   45.989 1.000 17.360  0 116 ARG A CZ  1 ? 
ATOM   862  N  NH1 . ARG A 1 116 ? 33.590 10.482  46.889 1.000 18.839  0 116 ARG A NH1 1 ? 
ATOM   863  N  NH2 . ARG A 1 116 ? 33.325 9.185   45.057 1.000 18.022  0 116 ARG A NH2 1 ? 
ATOM   864  N  N   . THR A 1 117 ? 27.538 14.334  49.076 1.000 16.180  0 117 THR A N   1 ? 
ATOM   865  C  CA  . THR A 1 117 ? 26.447 15.071  49.664 1.000 15.287  0 117 THR A CA  1 ? 
ATOM   866  C  C   . THR A 1 117 ? 25.281 14.125  49.946 1.000 15.635  0 117 THR A C   1 ? 
ATOM   867  O  O   . THR A 1 117 ? 25.177 13.051  49.331 1.000 14.925  0 117 THR A O   1 ? 
ATOM   868  C  CB  . THR A 1 117 ? 25.995 16.195  48.728 1.000 18.327  0 117 THR A CB  1 ? 
ATOM   869  O  OG1 . THR A 1 117 ? 25.355 15.602  47.601 1.000 19.568  0 117 THR A OG1 1 ? 
ATOM   870  C  CG2 . THR A 1 117 ? 27.148 17.069  48.246 1.000 20.260  0 117 THR A CG2 1 ? 
ATOM   871  N  N   . PRO A 1 118 ? 24.330 14.511  50.820 1.000 15.752  0 118 PRO A N   1 ? 
ATOM   872  C  CA  . PRO A 1 118 ? 23.121 13.709  50.998 1.000 16.389  0 118 PRO A CA  1 ? 
ATOM   873  C  C   . PRO A 1 118 ? 22.354 13.420  49.711 1.000 17.153  0 118 PRO A C   1 ? 
ATOM   874  O  O   . PRO A 1 118 ? 21.893 12.302  49.521 1.000 16.298  0 118 PRO A O   1 ? 
ATOM   875  C  CB  . PRO A 1 118 ? 22.314 14.465  52.047 1.000 18.309  0 118 PRO A CB  1 ? 
ATOM   876  C  CG  . PRO A 1 118 ? 23.332 15.265  52.826 1.000 19.031  0 118 PRO A CG  1 ? 
ATOM   877  C  CD  . PRO A 1 118 ? 24.418 15.581  51.825 1.000 16.918  0 118 PRO A CD  1 ? 
ATOM   878  N  N   . GLU A 1 119 ? 22.273 14.376  48.782 1.000 15.141  0 119 GLU A N   1 ? 
ATOM   879  C  CA  . GLU A 1 119 ? 21.642 14.129  47.489 1.000 17.500  0 119 GLU A CA  1 ? 
ATOM   880  C  C   . GLU A 1 119 ? 22.396 13.066  46.681 1.000 17.400  0 119 GLU A C   1 ? 
ATOM   881  O  O   . GLU A 1 119 ? 21.802 12.155  46.062 1.000 16.862  0 119 GLU A O   1 ? 
ATOM   882  C  CB  . GLU A 1 119 ? 21.513 15.454  46.746 1.000 19.369  0 119 GLU A CB  1 ? 
ATOM   883  C  CG  . GLU A 1 119 ? 20.953 15.310  45.334 1.000 21.743  0 119 GLU A CG  1 ? 
ATOM   884  C  CD  . GLU A 1 119 ? 21.942 15.032  44.212 1.000 23.129  0 119 GLU A CD  1 ? 
ATOM   885  O  OE1 . GLU A 1 119 ? 23.155 15.331  44.304 1.000 27.692  0 119 GLU A OE1 1 ? 
ATOM   886  O  OE2 . GLU A 1 119 ? 21.440 14.491  43.177 1.000 30.880  0 119 GLU A OE2 1 ? 
ATOM   887  N  N   . GLU A 1 120 ? 23.739 13.113  46.664 1.000 15.706  0 120 GLU A N   1 ? 
ATOM   888  C  CA  . GLU A 1 120 ? 24.529 12.106  45.976 1.000 15.586  0 120 GLU A CA  1 ? 
ATOM   889  C  C   . GLU A 1 120 ? 24.355 10.743  46.653 1.000 14.211  0 120 GLU A C   1 ? 
ATOM   890  O  O   . GLU A 1 120 ? 24.293 9.709   45.966 1.000 15.548  0 120 GLU A O   1 ? 
ATOM   891  C  CB  . GLU A 1 120 ? 25.992 12.513  46.045 1.000 16.199  0 120 GLU A CB  1 ? 
ATOM   892  C  CG  . GLU A 1 120 ? 26.283 13.641  45.060 1.000 18.672  0 120 GLU A CG  1 ? 
ATOM   893  C  CD  . GLU A 1 120 ? 27.622 14.345  45.219 1.000 23.785  0 120 GLU A CD  1 ? 
ATOM   894  O  OE1 . GLU A 1 120 ? 28.335 14.187  46.225 1.000 21.484  0 120 GLU A OE1 1 ? 
ATOM   895  O  OE2 . GLU A 1 120 ? 27.924 15.140  44.295 1.000 25.047  0 120 GLU A OE2 1 ? 
ATOM   896  N  N   . ILE A 1 121 ? 24.324 10.722  47.981 1.000 13.888  0 121 ILE A N   1 ? 
ATOM   897  C  CA  . ILE A 1 121 ? 24.212 9.458   48.705 1.000 14.134  0 121 ILE A CA  1 ? 
ATOM   898  C  C   . ILE A 1 121 ? 22.854 8.819   48.431 1.000 13.598  0 121 ILE A C   1 ? 
ATOM   899  O  O   . ILE A 1 121 ? 22.765 7.610   48.302 1.000 13.817  0 121 ILE A O   1 ? 
ATOM   900  C  CB  . ILE A 1 121 ? 24.448 9.680   50.203 1.000 15.457  0 121 ILE A CB  1 ? 
ATOM   901  C  CG1 . ILE A 1 121 ? 25.928 10.010  50.431 1.000 18.642  0 121 ILE A CG1 1 ? 
ATOM   902  C  CG2 . ILE A 1 121 ? 24.010 8.495   51.045 1.000 17.392  0 121 ILE A CG2 1 ? 
ATOM   903  C  CD1 . ILE A 1 121 ? 26.268 10.418  51.838 1.000 20.120  0 121 ILE A CD1 1 ? 
ATOM   904  N  N   . ARG A 1 122 ? 21.804 9.622   48.290 1.000 13.710  0 122 ARG A N   1 ? 
ATOM   905  C  CA  . ARG A 1 122 ? 20.496 9.077   47.930 1.000 16.600  0 122 ARG A CA  1 ? 
ATOM   906  C  C   . ARG A 1 122 ? 20.520 8.381   46.575 1.000 15.865  0 122 ARG A C   1 ? 
ATOM   907  O  O   . ARG A 1 122 ? 19.958 7.270   46.415 1.000 15.290  0 122 ARG A O   1 ? 
ATOM   908  C  CB  . ARG A 1 122 ? 19.453 10.191  47.974 1.000 18.799  0 122 ARG A CB  1 ? 
ATOM   909  C  CG  . ARG A 1 122 ? 18.090 9.791   47.435 1.000 21.169  0 122 ARG A CG  1 ? 
ATOM   910  C  CD  . ARG A 1 122 ? 17.125 10.958  47.577 1.000 27.415  0 122 ARG A CD  1 ? 
ATOM   911  N  NE  . ARG A 1 122 ? 15.823 10.539  47.032 1.000 33.043  0 122 ARG A NE  1 ? 
ATOM   912  C  CZ  . ARG A 1 122 ? 15.431 10.833  45.811 1.000 33.268  0 122 ARG A CZ  1 ? 
ATOM   913  N  NH1 . ARG A 1 122 ? 16.197 11.576  45.039 1.000 34.277  0 122 ARG A NH1 1 ? 
ATOM   914  N  NH2 . ARG A 1 122 ? 14.280 10.362  45.365 1.000 35.228  0 122 ARG A NH2 1 ? 
ATOM   915  N  N   . ARG A 1 123 ? 21.163 8.986   45.569 1.000 14.238  0 123 ARG A N   1 ? 
ATOM   916  C  CA  . ARG A 1 123 ? 21.292 8.406   44.252 1.000 16.812  0 123 ARG A CA  1 ? 
ATOM   917  C  C   . ARG A 1 123 ? 22.096 7.096   44.304 1.000 13.848  0 123 ARG A C   1 ? 
ATOM   918  O  O   . ARG A 1 123 ? 21.723 6.079   43.695 1.000 14.235  0 123 ARG A O   1 ? 
ATOM   919  C  CB  . ARG A 1 123 ? 21.889 9.485   43.346 1.000 23.789  0 123 ARG A CB  1 ? 
ATOM   920  C  CG  . ARG A 1 123 ? 22.126 9.161   41.891 1.000 34.752  0 123 ARG A CG  1 ? 
ATOM   921  C  CD  . ARG A 1 123 ? 21.788 10.328  40.946 1.000 41.288  0 123 ARG A CD  1 ? 
ATOM   922  N  NE  . ARG A 1 123 ? 21.827 9.765   39.590 1.000 50.309  0 123 ARG A NE  1 ? 
ATOM   923  C  CZ  . ARG A 1 123 ? 21.218 8.639   39.189 1.000 55.280  0 123 ARG A CZ  1 ? 
ATOM   924  N  NH1 . ARG A 1 123 ? 20.205 8.147   39.880 1.000 61.059  0 123 ARG A NH1 1 ? 
ATOM   925  N  NH2 . ARG A 1 123 ? 21.586 8.030   38.069 1.000 51.065  0 123 ARG A NH2 1 ? 
ATOM   926  N  N   . ILE A 1 124 ? 23.202 7.124   45.047 1.000 14.158  0 124 ILE A N   1 ? 
ATOM   927  C  CA  . ILE A 1 124 ? 24.031 5.935   45.247 1.000 12.882  0 124 ILE A CA  1 ? 
ATOM   928  C  C   . ILE A 1 124 ? 23.226 4.826   45.915 1.000 12.985  0 124 ILE A C   1 ? 
ATOM   929  O  O   . ILE A 1 124 ? 23.244 3.680   45.459 1.000 13.613  0 124 ILE A O   1 ? 
ATOM   930  C  CB  . ILE A 1 124 ? 25.258 6.295   46.101 1.000 13.533  0 124 ILE A CB  1 ? 
ATOM   931  C  CG1 . ILE A 1 124 ? 26.183 7.220   45.315 1.000 14.622  0 124 ILE A CG1 1 ? 
ATOM   932  C  CG2 . ILE A 1 124 ? 25.971 5.031   46.578 1.000 14.563  0 124 ILE A CG2 1 ? 
ATOM   933  C  CD1 . ILE A 1 124 ? 27.270 7.848   46.165 1.000 14.904  0 124 ILE A CD1 1 ? 
ATOM   934  N  N   . SER A 1 125 ? 22.497 5.167   46.966 1.000 15.093  0 125 SER A N   1 ? 
ATOM   935  C  CA  . SER A 1 125 ? 21.725 4.170   47.707 1.000 15.567  0 125 SER A CA  1 ? 
ATOM   936  C  C   . SER A 1 125 ? 20.679 3.512   46.809 1.000 14.629  0 125 SER A C   1 ? 
ATOM   937  O  O   . SER A 1 125 ? 20.450 2.294   46.843 1.000 15.950  0 125 SER A O   1 ? 
ATOM   938  C  CB  . SER A 1 125 ? 21.099 4.844   48.882 1.000 18.271  0 125 SER A CB  1 ? 
ATOM   939  O  OG  . SER A 1 125 ? 20.484 3.871   49.714 1.000 23.165  0 125 SER A OG  1 ? 
ATOM   940  N  N   . GLN A 1 126 ? 20.025 4.323   45.987 1.000 15.132  0 126 GLN A N   1 ? 
ATOM   941  C  CA  . GLN A 1 126 ? 18.966 3.794   45.132 1.000 16.209  0 126 GLN A CA  1 ? 
ATOM   942  C  C   . GLN A 1 126 ? 19.559 2.940   44.038 1.000 15.619  0 126 GLN A C   1 ? 
ATOM   943  O  O   . GLN A 1 126 ? 18.995 1.889   43.681 1.000 13.538  0 126 GLN A O   1 ? 
ATOM   944  C  CB  . GLN A 1 126 ? 18.230 4.920   44.422 1.000 20.155  0 126 GLN A CB  1 ? 
ATOM   945  C  CG  . GLN A 1 126 ? 17.365 5.744   45.344 1.000 26.875  0 126 GLN A CG  1 ? 
ATOM   946  C  CD  . GLN A 1 126 ? 16.754 6.933   44.629 1.000 38.644  0 126 GLN A CD  1 ? 
ATOM   947  O  OE1 . GLN A 1 126 ? 17.309 7.471   43.657 1.000 48.361  0 126 GLN A OE1 1 ? 
ATOM   948  N  NE2 . GLN A 1 126 ? 15.633 7.390   45.156 1.000 44.351  0 126 GLN A NE2 1 ? 
ATOM   949  N  N   . THR A 1 127 ? 20.699 3.392   43.467 1.000 13.237  0 127 THR A N   1 ? 
ATOM   950  C  CA  . THR A 1 127 ? 21.343 2.625   42.411 1.000 13.363  0 127 THR A CA  1 ? 
ATOM   951  C  C   . THR A 1 127 ? 21.874 1.290   42.961 1.000 12.798  0 127 THR A C   1 ? 
ATOM   952  O  O   . THR A 1 127 ? 21.804 0.258   42.263 1.000 14.130  0 127 THR A O   1 ? 
ATOM   953  C  CB  . THR A 1 127 ? 22.416 3.440   41.670 1.000 13.236  0 127 THR A CB  1 ? 
ATOM   954  O  OG1 . THR A 1 127 ? 21.730 4.562   41.096 1.000 16.152  0 127 THR A OG1 1 ? 
ATOM   955  C  CG2 . THR A 1 127 ? 23.118 2.655   40.579 1.000 13.917  0 127 THR A CG2 1 ? 
ATOM   956  N  N   . TYR A 1 128 ? 22.438 1.294   44.180 1.000 12.628  0 128 TYR A N   1 ? 
ATOM   957  C  CA  . TYR A 1 128 ? 22.946 0.072   44.774 1.000 11.982  0 128 TYR A CA  1 ? 
ATOM   958  C  C   . TYR A 1 128 ? 21.802 -0.928  44.904 1.000 12.455  0 128 TYR A C   1 ? 
ATOM   959  O  O   . TYR A 1 128 ? 21.954 -2.123  44.621 1.000 11.647  0 128 TYR A O   1 ? 
ATOM   960  C  CB  . TYR A 1 128 ? 23.602 0.446   46.101 1.000 12.098  0 128 TYR A CB  1 ? 
ATOM   961  C  CG  . TYR A 1 128 ? 24.317 -0.657  46.878 1.000 12.986  0 128 TYR A CG  1 ? 
ATOM   962  C  CD1 . TYR A 1 128 ? 23.627 -1.580  47.664 1.000 11.414  0 128 TYR A CD1 1 ? 
ATOM   963  C  CD2 . TYR A 1 128 ? 25.714 -0.694  46.902 1.000 13.196  0 128 TYR A CD2 1 ? 
ATOM   964  C  CE1 . TYR A 1 128 ? 24.312 -2.534  48.398 1.000 13.758  0 128 TYR A CE1 1 ? 
ATOM   965  C  CE2 . TYR A 1 128 ? 26.393 -1.681  47.584 1.000 13.786  0 128 TYR A CE2 1 ? 
ATOM   966  C  CZ  . TYR A 1 128 ? 25.695 -2.560  48.378 1.000 15.378  0 128 TYR A CZ  1 ? 
ATOM   967  O  OH  . TYR A 1 128 ? 26.441 -3.514  49.038 1.000 16.300  0 128 TYR A OH  1 ? 
ATOM   968  N  N   . GLN A 1 129 ? 20.672 -0.449  45.407 1.000 13.029  0 129 GLN A N   1 ? 
ATOM   969  C  CA  . GLN A 1 129 ? 19.510 -1.314  45.592 1.000 13.663  0 129 GLN A CA  1 ? 
ATOM   970  C  C   . GLN A 1 129 ? 19.064 -1.894  44.251 1.000 14.895  0 129 GLN A C   1 ? 
ATOM   971  O  O   . GLN A 1 129 ? 18.801 -3.100  44.162 1.000 14.380  0 129 GLN A O   1 ? 
ATOM   972  C  CB  . GLN A 1 129 ? 18.418 -0.498  46.281 1.000 15.210  0 129 GLN A CB  1 ? 
ATOM   973  C  CG  . GLN A 1 129 ? 17.220 -1.333  46.714 1.000 16.924  0 129 GLN A CG  1 ? 
ATOM   974  C  CD  . GLN A 1 129 ? 17.363 -1.842  48.124 1.000 19.680  0 129 GLN A CD  1 ? 
ATOM   975  O  OE1 . GLN A 1 129 ? 17.158 -3.037  48.430 1.000 24.577  0 129 GLN A OE1 1 ? 
ATOM   976  N  NE2 . GLN A 1 129 ? 17.709 -0.925  49.022 1.000 19.493  0 129 GLN A NE2 1 ? 
ATOM   977  N  N   . GLN A 1 130 ? 19.028 -1.077  43.198 1.000 14.730  0 130 GLN A N   1 ? 
ATOM   978  C  CA  . GLN A 1 130 ? 18.554 -1.490  41.891 1.000 16.347  0 130 GLN A CA  1 ? 
ATOM   979  C  C   . GLN A 1 130 ? 19.485 -2.528  41.275 1.000 16.110  0 130 GLN A C   1 ? 
ATOM   980  O  O   . GLN A 1 130 ? 19.027 -3.498  40.639 1.000 15.140  0 130 GLN A O   1 ? 
ATOM   981  C  CB  . GLN A 1 130 ? 18.470 -0.232  41.035 1.000 20.628  0 130 GLN A CB  1 ? 
ATOM   982  C  CG  . GLN A 1 130 ? 17.378 -0.223  39.995 1.000 28.493  0 130 GLN A CG  1 ? 
ATOM   983  C  CD  . GLN A 1 130 ? 17.176 1.179   39.468 1.000 34.648  0 130 GLN A CD  1 ? 
ATOM   984  O  OE1 . GLN A 1 130 ? 16.522 2.023   40.095 1.000 41.455  0 130 GLN A OE1 1 ? 
ATOM   985  N  NE2 . GLN A 1 130 ? 17.761 1.426   38.312 1.000 37.339  0 130 GLN A NE2 1 ? 
ATOM   986  N  N   . GLN A 1 131 ? 20.795 -2.323  41.454 1.000 15.443  0 131 GLN A N   1 ? 
ATOM   987  C  CA  . GLN A 1 131 ? 21.790 -3.164  40.835 1.000 15.418  0 131 GLN A CA  1 ? 
ATOM   988  C  C   . GLN A 1 131 ? 21.886 -4.513  41.509 1.000 17.561  0 131 GLN A C   1 ? 
ATOM   989  O  O   . GLN A 1 131 ? 21.972 -5.543  40.829 1.000 21.815  0 131 GLN A O   1 ? 
ATOM   990  C  CB  . GLN A 1 131 ? 23.172 -2.496  40.907 1.000 18.036  0 131 GLN A CB  1 ? 
ATOM   991  C  CG  . GLN A 1 131 ? 23.289 -1.292  39.998 1.000 19.598  0 131 GLN A CG  1 ? 
ATOM   992  C  CD  . GLN A 1 131 ? 23.392 -1.673  38.539 1.000 22.050  0 131 GLN A CD  1 ? 
ATOM   993  O  OE1 . GLN A 1 131 ? 24.206 -2.496  38.142 1.000 24.937  0 131 GLN A OE1 1 ? 
ATOM   994  N  NE2 . GLN A 1 131 ? 22.529 -1.086  37.742 1.000 26.274  0 131 GLN A NE2 1 ? 
ATOM   995  N  N   . TYR A 1 132 ? 21.884 -4.524  42.841 1.000 14.435  0 132 TYR A N   1 ? 
ATOM   996  C  CA  . TYR A 1 132 ? 22.234 -5.739  43.567 1.000 14.435  0 132 TYR A CA  1 ? 
ATOM   997  C  C   . TYR A 1 132 ? 21.038 -6.372  44.253 1.000 15.927  0 132 TYR A C   1 ? 
ATOM   998  O  O   . TYR A 1 132 ? 21.161 -7.520  44.727 1.000 19.757  0 132 TYR A O   1 ? 
ATOM   999  C  CB  . TYR A 1 132 ? 23.294 -5.443  44.629 1.000 15.249  0 132 TYR A CB  1 ? 
ATOM   1000 C  CG  . TYR A 1 132 ? 24.546 -4.847  44.010 1.000 15.851  0 132 TYR A CG  1 ? 
ATOM   1001 C  CD1 . TYR A 1 132 ? 25.258 -5.534  43.035 1.000 17.547  0 132 TYR A CD1 1 ? 
ATOM   1002 C  CD2 . TYR A 1 132 ? 24.984 -3.578  44.365 1.000 15.984  0 132 TYR A CD2 1 ? 
ATOM   1003 C  CE1 . TYR A 1 132 ? 26.360 -4.967  42.418 1.000 17.531  0 132 TYR A CE1 1 ? 
ATOM   1004 C  CE2 . TYR A 1 132 ? 26.088 -3.001  43.769 1.000 15.372  0 132 TYR A CE2 1 ? 
ATOM   1005 C  CZ  . TYR A 1 132 ? 26.769 -3.698  42.788 1.000 16.707  0 132 TYR A CZ  1 ? 
ATOM   1006 O  OH  . TYR A 1 132 ? 27.884 -3.154  42.229 1.000 20.178  0 132 TYR A OH  1 ? 
ATOM   1007 N  N   . GLY A 1 133 ? 19.931 -5.651  44.430 1.000 14.345  0 133 GLY A N   1 ? 
ATOM   1008 C  CA  . GLY A 1 133 ? 18.807 -6.169  45.207 1.000 15.502  0 133 GLY A CA  1 ? 
ATOM   1009 C  C   . GLY A 1 133 ? 19.159 -6.339  46.676 1.000 15.982  0 133 GLY A C   1 ? 
ATOM   1010 O  O   . GLY A 1 133 ? 18.689 -7.248  47.373 1.000 16.427  0 133 GLY A O   1 ? 
ATOM   1011 N  N   . ARG A 1 134 ? 20.012 -5.412  47.160 1.000 16.973  0 134 ARG A N   1 ? 
ATOM   1012 C  CA  . ARG A 1 134 ? 20.513 -5.425  48.509 1.000 18.096  0 134 ARG A CA  1 ? 
ATOM   1013 C  C   . ARG A 1 134 ? 20.448 -3.986  49.005 1.000 17.702  0 134 ARG A C   1 ? 
ATOM   1014 O  O   . ARG A 1 134 ? 20.641 -3.077  48.227 1.000 14.775  0 134 ARG A O   1 ? 
ATOM   1015 C  CB  . ARG A 1 134 ? 22.009 -5.796  48.540 1.000 20.260  0 134 ARG A CB  1 ? 
ATOM   1016 C  CG  . ARG A 1 134 ? 22.351 -7.133  47.886 1.000 22.156  0 134 ARG A CG  1 ? 
ATOM   1017 C  CD  . ARG A 1 134 ? 23.807 -7.534  47.965 1.000 22.059  0 134 ARG A CD  1 ? 
ATOM   1018 N  NE  . ARG A 1 134 ? 24.268 -7.682  49.351 1.000 22.786  0 134 ARG A NE  1 ? 
ATOM   1019 C  CZ  . ARG A 1 134 ? 24.570 -8.837  49.950 1.000 28.028  0 134 ARG A CZ  1 ? 
ATOM   1020 N  NH1 . ARG A 1 134 ? 24.503 -9.984  49.292 1.000 30.367  0 134 ARG A NH1 1 ? 
ATOM   1021 N  NH2 . ARG A 1 134 ? 24.899 -8.884  51.223 1.000 25.247  0 134 ARG A NH2 1 ? 
ATOM   1022 N  N   . SER A 1 135 ? 20.149 -3.819  50.283 1.000 18.433  0 135 SER A N   1 ? 
ATOM   1023 C  CA  . SER A 1 135 ? 20.214 -2.524  50.937 1.000 17.099  0 135 SER A CA  1 ? 
ATOM   1024 C  C   . SER A 1 135 ? 21.662 -2.128  51.233 1.000 14.382  0 135 SER A C   1 ? 
ATOM   1025 O  O   . SER A 1 135 ? 22.400 -2.866  51.895 1.000 16.284  0 135 SER A O   1 ? 
ATOM   1026 C  CB  . SER A 1 135 ? 19.366 -2.617  52.180 1.000 21.515  0 135 SER A CB  1 ? 
ATOM   1027 O  OG  . SER A 1 135 ? 19.582 -1.570  53.104 1.000 19.428  0 135 SER A OG  1 ? 
ATOM   1028 N  N   . LEU A 1 136 ? 22.003 -0.887  50.845 1.000 15.431  0 136 LEU A N   1 ? 
ATOM   1029 C  CA  . LEU A 1 136 ? 23.301 -0.333  51.209 1.000 15.691  0 136 LEU A CA  1 ? 
ATOM   1030 C  C   . LEU A 1 136 ? 23.444 -0.299  52.730 1.000 15.163  0 136 LEU A C   1 ? 
ATOM   1031 O  O   . LEU A 1 136 ? 24.457 -0.765  53.259 1.000 14.676  0 136 LEU A O   1 ? 
ATOM   1032 C  CB  . LEU A 1 136 ? 23.486 1.039   50.575 1.000 15.479  0 136 LEU A CB  1 ? 
ATOM   1033 C  CG  . LEU A 1 136 ? 24.709 1.841   51.028 1.000 16.815  0 136 LEU A CG  1 ? 
ATOM   1034 C  CD1 . LEU A 1 136 ? 25.964 1.092   50.653 1.000 17.711  0 136 LEU A CD1 1 ? 
ATOM   1035 C  CD2 . LEU A 1 136 ? 24.700 3.218   50.420 1.000 17.517  0 136 LEU A CD2 1 ? 
ATOM   1036 N  N   . GLU A 1 137 ? 22.429 0.219   53.406 1.000 16.822  0 137 GLU A N   1 ? 
ATOM   1037 C  CA  . GLU A 1 137 ? 22.444 0.316   54.860 1.000 18.251  0 137 GLU A CA  1 ? 
ATOM   1038 C  C   . GLU A 1 137 ? 22.577 -1.067  55.494 1.000 17.327  0 137 GLU A C   1 ? 
ATOM   1039 O  O   . GLU A 1 137 ? 23.302 -1.203  56.470 1.000 19.273  0 137 GLU A O   1 ? 
ATOM   1040 C  CB  . GLU A 1 137 ? 21.161 0.961   55.384 1.000 19.081  0 137 GLU A CB  1 ? 
ATOM   1041 C  CG  . GLU A 1 137 ? 21.160 2.467   55.165 1.000 23.200  0 137 GLU A CG  1 ? 
ATOM   1042 C  CD  . GLU A 1 137 ? 19.862 3.149   55.596 1.000 27.001  0 137 GLU A CD  1 ? 
ATOM   1043 O  OE1 . GLU A 1 137 ? 19.304 2.653   56.582 1.000 28.489  0 137 GLU A OE1 1 ? 
ATOM   1044 O  OE2 . GLU A 1 137 ? 19.425 4.133   54.955 1.000 31.133  0 137 GLU A OE2 1 ? 
ATOM   1045 N  N   . ASP A 1 138 ? 21.874 -2.085  54.981 1.000 17.243  0 138 ASP A N   1 ? 
ATOM   1046 C  CA  . ASP A 1 138 ? 21.959 -3.418  55.573 1.000 18.844  0 138 ASP A CA  1 ? 
ATOM   1047 C  C   . ASP A 1 138 ? 23.345 -4.032  55.387 1.000 16.592  0 138 ASP A C   1 ? 
ATOM   1048 O  O   . ASP A 1 138 ? 23.883 -4.708  56.257 1.000 18.981  0 138 ASP A O   1 ? 
ATOM   1049 C  CB  . ASP A 1 138 ? 20.973 -4.398  54.958 1.000 22.170  0 138 ASP A CB  1 ? 
ATOM   1050 C  CG  . ASP A 1 138 ? 19.520 -4.196  55.361 1.000 29.671  0 138 ASP A CG  1 ? 
ATOM   1051 O  OD1 . ASP A 1 138 ? 19.288 -3.665  56.457 1.000 32.071  0 138 ASP A OD1 1 ? 
ATOM   1052 O  OD2 . ASP A 1 138 ? 18.636 -4.564  54.564 1.000 34.402  0 138 ASP A OD2 1 ? 
ATOM   1053 N  N   . ASP A 1 139 ? 23.959 -3.799  54.219 1.000 15.369  0 139 ASP A N   1 ? 
ATOM   1054 C  CA  . ASP A 1 139 ? 25.305 -4.284  53.991 1.000 15.264  0 139 ASP A CA  1 ? 
ATOM   1055 C  C   . ASP A 1 139 ? 26.302 -3.611  54.935 1.000 15.298  0 139 ASP A C   1 ? 
ATOM   1056 O  O   . ASP A 1 139 ? 27.160 -4.266  55.494 1.000 15.783  0 139 ASP A O   1 ? 
ATOM   1057 C  CB  . ASP A 1 139 ? 25.637 -4.204  52.511 1.000 13.995  0 139 ASP A CB  1 ? 
ATOM   1058 C  CG  . ASP A 1 139 ? 24.976 -5.283  51.673 1.000 19.317  0 139 ASP A CG  1 ? 
ATOM   1059 O  OD1 . ASP A 1 139 ? 24.339 -6.195  52.281 1.000 20.401  0 139 ASP A OD1 1 ? 
ATOM   1060 O  OD2 . ASP A 1 139 ? 25.170 -5.246  50.458 1.000 18.948  0 139 ASP A OD2 1 ? 
ATOM   1061 N  N   . ILE A 1 140 ? 26.189 -2.284  55.108 1.000 17.018  0 140 ILE A N   1 ? 
ATOM   1062 C  CA  . ILE A 1 140 ? 27.014 -1.571  56.075 1.000 16.575  0 140 ILE A CA  1 ? 
ATOM   1063 C  C   . ILE A 1 140 ? 26.819 -2.173  57.474 1.000 17.454  0 140 ILE A C   1 ? 
ATOM   1064 O  O   . ILE A 1 140 ? 27.805 -2.421  58.175 1.000 20.065  0 140 ILE A O   1 ? 
ATOM   1065 C  CB  . ILE A 1 140 ? 26.685 -0.061  56.047 1.000 17.041  0 140 ILE A CB  1 ? 
ATOM   1066 C  CG1 . ILE A 1 140 ? 27.134 0.577   54.786 1.000 18.504  0 140 ILE A CG1 1 ? 
ATOM   1067 C  CG2 . ILE A 1 140 ? 27.316 0.596   57.277 1.000 17.565  0 140 ILE A CG2 1 ? 
ATOM   1068 C  CD1 . ILE A 1 140 ? 26.510 1.941   54.544 1.000 19.730  0 140 ILE A CD1 1 ? 
ATOM   1069 N  N   . ARG A 1 141 ? 25.578 -2.416  57.884 1.000 19.103  0 141 ARG A N   1 ? 
ATOM   1070 C  CA  . ARG A 1 141 ? 25.310 -2.994  59.207 1.000 21.822  0 141 ARG A CA  1 ? 
ATOM   1071 C  C   . ARG A 1 141 ? 26.022 -4.346  59.370 1.000 25.425  0 141 ARG A C   1 ? 
ATOM   1072 O  O   . ARG A 1 141 ? 26.658 -4.586  60.385 1.000 26.797  0 141 ARG A O   1 ? 
ATOM   1073 C  CB  . ARG A 1 141 ? 23.817 -3.157  59.498 1.000 25.371  0 141 ARG A CB  1 ? 
ATOM   1074 C  CG  . ARG A 1 141 ? 23.056 -1.860  59.734 1.000 30.627  0 141 ARG A CG  1 ? 
ATOM   1075 C  CD  . ARG A 1 141 ? 21.544 -2.048  59.902 1.000 38.249  0 141 ARG A CD  1 ? 
ATOM   1076 N  NE  . ARG A 1 141 ? 20.858 -0.752  59.920 1.000 44.229  0 141 ARG A NE  1 ? 
ATOM   1077 C  CZ  . ARG A 1 141 ? 19.903 -0.343  59.086 1.000 44.721  0 141 ARG A CZ  1 ? 
ATOM   1078 N  NH1 . ARG A 1 141 ? 19.341 -1.176  58.221 1.000 47.204  0 141 ARG A NH1 1 ? 
ATOM   1079 N  NH2 . ARG A 1 141 ? 19.491 0.906   59.143 1.000 43.476  0 141 ARG A NH2 1 ? 
ATOM   1080 N  N   . SER A 1 142 ? 25.995 -5.200  58.354 1.000 20.338  0 142 SER A N   1 ? 
ATOM   1081 C  CA  . SER A 1 142 ? 26.667 -6.492  58.430 1.000 21.025  0 142 SER A CA  1 ? 
ATOM   1082 C  C   . SER A 1 142 ? 28.186 -6.400  58.427 1.000 21.391  0 142 SER A C   1 ? 
ATOM   1083 O  O   . SER A 1 142 ? 28.877 -7.314  58.887 1.000 23.668  0 142 SER A O   1 ? 
ATOM   1084 C  CB  . SER A 1 142 ? 26.236 -7.370  57.310 1.000 22.221  0 142 SER A CB  1 ? 
ATOM   1085 O  OG  . SER A 1 142 ? 24.912 -7.796  57.543 1.000 26.814  0 142 SER A OG  1 ? 
ATOM   1086 N  N   . ASP A 1 143 ? 28.751 -5.363  57.801 1.000 20.712  0 143 ASP A N   1 ? 
ATOM   1087 C  CA  . ASP A 1 143 ? 30.167 -5.367  57.493 1.000 20.008  0 143 ASP A CA  1 ? 
ATOM   1088 C  C   . ASP A 1 143 ? 30.957 -4.446  58.414 1.000 20.879  0 143 ASP A C   1 ? 
ATOM   1089 O  O   . ASP A 1 143 ? 32.180 -4.487  58.356 1.000 21.874  0 143 ASP A O   1 ? 
ATOM   1090 C  CB  . ASP A 1 143 ? 30.361 -5.155  55.996 1.000 22.597  0 143 ASP A CB  1 ? 
ATOM   1091 C  CG  . ASP A 1 143 ? 29.781 -6.297  55.167 1.000 30.034  0 143 ASP A CG  1 ? 
ATOM   1092 O  OD1 . ASP A 1 143 ? 30.112 -7.441  55.477 1.000 35.333  0 143 ASP A OD1 1 ? 
ATOM   1093 O  OD2 . ASP A 1 143 ? 28.917 -6.055  54.285 1.000 40.744  0 143 ASP A OD2 1 ? 
ATOM   1094 N  N   . THR A 1 144 ? 30.282 -3.712  59.318 1.000 17.976  0 144 THR A N   1 ? 
ATOM   1095 C  CA  . THR A 1 144 ? 30.944 -2.873  60.300 1.000 19.805  0 144 THR A CA  1 ? 
ATOM   1096 C  C   . THR A 1 144 ? 30.229 -3.066  61.632 1.000 21.586  0 144 THR A C   1 ? 
ATOM   1097 O  O   . THR A 1 144 ? 29.095 -3.529  61.625 1.000 24.348  0 144 THR A O   1 ? 
ATOM   1098 C  CB  . THR A 1 144 ? 30.917 -1.416  59.814 1.000 18.631  0 144 THR A CB  1 ? 
ATOM   1099 O  OG1 . THR A 1 144 ? 29.569 -0.983  59.816 1.000 19.784  0 144 THR A OG1 1 ? 
ATOM   1100 C  CG2 . THR A 1 144 ? 31.539 -1.293  58.437 1.000 20.639  0 144 THR A CG2 1 ? 
ATOM   1101 N  N   . SER A 1 145 ? 30.885 -2.615  62.706 1.000 23.266  0 145 SER A N   1 ? 
ATOM   1102 C  CA  . SER A 1 145 ? 30.440 -2.855  64.062 1.000 25.560  0 145 SER A CA  1 ? 
ATOM   1103 C  C   . SER A 1 145 ? 30.534 -1.588  64.920 1.000 26.171  0 145 SER A C   1 ? 
ATOM   1104 O  O   . SER A 1 145 ? 31.309 -0.655  64.637 1.000 24.140  0 145 SER A O   1 ? 
ATOM   1105 C  CB  . SER A 1 145 ? 31.225 -4.004  64.665 1.000 27.332  0 145 SER A CB  1 ? 
ATOM   1106 O  OG  . SER A 1 145 ? 32.565 -3.614  64.934 1.000 31.581  0 145 SER A OG  1 ? 
ATOM   1107 N  N   . PHE A 1 146 ? 29.706 -1.593  65.979 1.000 23.144  0 146 PHE A N   1 ? 
ATOM   1108 C  CA  . PHE A 1 146 ? 29.842 -0.677  67.105 1.000 24.851  0 146 PHE A CA  1 ? 
ATOM   1109 C  C   . PHE A 1 146 ? 29.632 0.773   66.639 1.000 20.918  0 146 PHE A C   1 ? 
ATOM   1110 O  O   . PHE A 1 146 ? 28.743 1.040   65.837 1.000 20.156  0 146 PHE A O   1 ? 
ATOM   1111 C  CB  . PHE A 1 146 ? 31.192 -0.985  67.759 1.000 26.582  0 146 PHE A CB  1 ? 
ATOM   1112 C  CG  . PHE A 1 146 ? 31.392 -2.426  68.236 1.000 29.361  0 146 PHE A CG  1 ? 
ATOM   1113 C  CD1 . PHE A 1 146 ? 30.481 -3.038  69.094 1.000 35.996  0 146 PHE A CD1 1 ? 
ATOM   1114 C  CD2 . PHE A 1 146 ? 32.502 -3.158  67.821 1.000 35.557  0 146 PHE A CD2 1 ? 
ATOM   1115 C  CE1 . PHE A 1 146 ? 30.679 -4.350  69.525 1.000 38.146  0 146 PHE A CE1 1 ? 
ATOM   1116 C  CE2 . PHE A 1 146 ? 32.689 -4.473  68.235 1.000 35.306  0 146 PHE A CE2 1 ? 
ATOM   1117 C  CZ  . PHE A 1 146 ? 31.771 -5.069  69.077 1.000 35.191  0 146 PHE A CZ  1 ? 
ATOM   1118 N  N   . MET A 1 147 ? 30.398 1.705   67.221 1.000 22.365  0 147 MET A N   1 ? 
ATOM   1119 C  CA  . MET A 1 147 ? 30.126 3.119   66.988 1.000 22.294  0 147 MET A CA  1 ? 
ATOM   1120 C  C   . MET A 1 147 ? 30.425 3.505   65.531 1.000 20.353  0 147 MET A C   1 ? 
ATOM   1121 O  O   . MET A 1 147 ? 29.686 4.314   64.974 1.000 20.086  0 147 MET A O   1 ? 
ATOM   1122 C  CB  . MET A 1 147 ? 30.906 4.029   67.947 1.000 23.626  0 147 MET A CB  1 ? 
ATOM   1123 C  CG  . MET A 1 147 ? 30.372 4.057   69.403 1.000 27.181  0 147 MET A CG  1 ? 
ATOM   1124 S  SD  . MET A 1 147 ? 28.646 4.533   69.565 1.000 32.267  0 147 MET A SD  1 ? 
ATOM   1125 C  CE  . MET A 1 147 ? 28.500 6.055   68.621 1.000 34.589  0 147 MET A CE  1 ? 
ATOM   1126 N  N   . PHE A 1 148 ? 31.449 2.869   64.928 1.000 20.638  0 148 PHE A N   1 ? 
ATOM   1127 C  CA  . PHE A 1 148 ? 31.772 3.065   63.512 1.000 19.227  0 148 PHE A CA  1 ? 
ATOM   1128 C  C   . PHE A 1 148 ? 30.583 2.747   62.614 1.000 18.800  0 148 PHE A C   1 ? 
ATOM   1129 O  O   . PHE A 1 148 ? 30.219 3.513   61.724 1.000 19.608  0 148 PHE A O   1 ? 
ATOM   1130 C  CB  . PHE A 1 148 ? 32.979 2.200   63.146 1.000 20.005  0 148 PHE A CB  1 ? 
ATOM   1131 C  CG  . PHE A 1 148 ? 33.431 2.270   61.694 1.000 21.944  0 148 PHE A CG  1 ? 
ATOM   1132 C  CD1 . PHE A 1 148 ? 33.573 3.488   61.043 1.000 21.987  0 148 PHE A CD1 1 ? 
ATOM   1133 C  CD2 . PHE A 1 148 ? 33.749 1.113   60.987 1.000 21.701  0 148 PHE A CD2 1 ? 
ATOM   1134 C  CE1 . PHE A 1 148 ? 33.988 3.562   59.728 1.000 22.540  0 148 PHE A CE1 1 ? 
ATOM   1135 C  CE2 . PHE A 1 148 ? 34.179 1.187   59.668 1.000 21.803  0 148 PHE A CE2 1 ? 
ATOM   1136 C  CZ  . PHE A 1 148 ? 34.291 2.401   59.032 1.000 21.806  0 148 PHE A CZ  1 ? 
ATOM   1137 N  N   . GLN A 1 149 ? 29.968 1.573   62.828 1.000 19.771  0 149 GLN A N   1 ? 
ATOM   1138 C  CA  . GLN A 1 149 ? 28.744 1.213   62.133 1.000 19.772  0 149 GLN A CA  1 ? 
ATOM   1139 C  C   . GLN A 1 149 ? 27.664 2.300   62.234 1.000 19.340  0 149 GLN A C   1 ? 
ATOM   1140 O  O   . GLN A 1 149 ? 26.996 2.640   61.275 1.000 18.854  0 149 GLN A O   1 ? 
ATOM   1141 C  CB  . GLN A 1 149 ? 28.204 -0.105  62.685 1.000 22.718  0 149 GLN A CB  1 ? 
ATOM   1142 C  CG  . GLN A 1 149 ? 26.946 -0.576  61.982 1.000 23.859  0 149 GLN A CG  1 ? 
ATOM   1143 C  CD  . GLN A 1 149 ? 26.155 -1.552  62.812 1.000 30.133  0 149 GLN A CD  1 ? 
ATOM   1144 O  OE1 . GLN A 1 149 ? 25.145 -1.183  63.420 1.000 30.595  0 149 GLN A OE1 1 ? 
ATOM   1145 N  NE2 . GLN A 1 149 ? 26.652 -2.779  62.877 1.000 26.320  0 149 GLN A NE2 1 ? 
ATOM   1146 N  N   . ARG A 1 150 ? 27.430 2.825   63.438 1.000 19.230  0 150 ARG A N   1 ? 
ATOM   1147 C  CA  . ARG A 1 150 ? 26.368 3.804   63.620 1.000 20.546  0 150 ARG A CA  1 ? 
ATOM   1148 C  C   . ARG A 1 150 ? 26.628 5.044   62.762 1.000 18.108  0 150 ARG A C   1 ? 
ATOM   1149 O  O   . ARG A 1 150 ? 25.690 5.599   62.234 1.000 18.503  0 150 ARG A O   1 ? 
ATOM   1150 C  CB  . ARG A 1 150 ? 26.217 4.115   65.110 1.000 22.850  0 150 ARG A CB  1 ? 
ATOM   1151 C  CG  . ARG A 1 150 ? 25.700 2.937   65.918 1.000 27.150  0 150 ARG A CG  1 ? 
ATOM   1152 C  CD  . ARG A 1 150 ? 25.478 3.306   67.364 1.000 27.898  0 150 ARG A CD  1 ? 
ATOM   1153 N  NE  . ARG A 1 150 ? 24.424 4.305   67.578 1.000 29.045  0 150 ARG A NE  1 ? 
ATOM   1154 C  CZ  . ARG A 1 150 ? 24.123 4.880   68.754 1.000 31.984  0 150 ARG A CZ  1 ? 
ATOM   1155 N  NH1 . ARG A 1 150 ? 24.810 4.606   69.846 1.000 34.401  0 150 ARG A NH1 1 ? 
ATOM   1156 N  NH2 . ARG A 1 150 ? 23.135 5.743   68.827 1.000 31.096  0 150 ARG A NH2 1 ? 
ATOM   1157 N  N   . VAL A 1 151 ? 27.895 5.481   62.687 1.000 16.990  0 151 VAL A N   1 ? 
ATOM   1158 C  CA  . VAL A 1 151 ? 28.261 6.644   61.891 1.000 17.007  0 151 VAL A CA  1 ? 
ATOM   1159 C  C   . VAL A 1 151 ? 27.946 6.358   60.424 1.000 16.166  0 151 VAL A C   1 ? 
ATOM   1160 O  O   . VAL A 1 151 ? 27.325 7.143   59.762 1.000 15.297  0 151 VAL A O   1 ? 
ATOM   1161 C  CB  . VAL A 1 151 ? 29.718 7.099   62.068 1.000 16.757  0 151 VAL A CB  1 ? 
ATOM   1162 C  CG1 . VAL A 1 151 ? 30.094 8.184   61.061 1.000 17.734  0 151 VAL A CG1 1 ? 
ATOM   1163 C  CG2 . VAL A 1 151 ? 30.030 7.555   63.498 1.000 18.565  0 151 VAL A CG2 1 ? 
ATOM   1164 N  N   . LEU A 1 152 ? 28.395 5.215   59.921 1.000 17.800  0 152 LEU A N   1 ? 
ATOM   1165 C  CA  . LEU A 1 152 ? 28.219 4.941   58.502 1.000 18.865  0 152 LEU A CA  1 ? 
ATOM   1166 C  C   . LEU A 1 152 ? 26.744 4.743   58.155 1.000 18.222  0 152 LEU A C   1 ? 
ATOM   1167 O  O   . LEU A 1 152 ? 26.302 5.185   57.115 1.000 17.504  0 152 LEU A O   1 ? 
ATOM   1168 C  CB  . LEU A 1 152 ? 29.027 3.704   58.120 1.000 18.622  0 152 LEU A CB  1 ? 
ATOM   1169 C  CG  . LEU A 1 152 ? 30.540 3.807   58.193 1.000 21.042  0 152 LEU A CG  1 ? 
ATOM   1170 C  CD1 . LEU A 1 152 ? 31.109 2.572   57.526 1.000 25.207  0 152 LEU A CD1 1 ? 
ATOM   1171 C  CD2 . LEU A 1 152 ? 31.067 5.071   57.574 1.000 22.617  0 152 LEU A CD2 1 ? 
ATOM   1172 N  N   . VAL A 1 153 ? 25.965 4.064   59.010 1.000 20.697  0 153 VAL A N   1 ? 
ATOM   1173 C  CA  . VAL A 1 153 ? 24.539 3.930   58.747 1.000 21.412  0 153 VAL A CA  1 ? 
ATOM   1174 C  C   . VAL A 1 153 ? 23.897 5.310   58.663 1.000 20.524  0 153 VAL A C   1 ? 
ATOM   1175 O  O   . VAL A 1 153 ? 23.100 5.599   57.791 1.000 20.716  0 153 VAL A O   1 ? 
ATOM   1176 C  CB  . VAL A 1 153 ? 23.860 3.037   59.803 1.000 24.355  0 153 VAL A CB  1 ? 
ATOM   1177 C  CG1 . VAL A 1 153 ? 22.335 3.125   59.737 1.000 24.277  0 153 VAL A CG1 1 ? 
ATOM   1178 C  CG2 . VAL A 1 153 ? 24.355 1.601   59.704 1.000 25.051  0 153 VAL A CG2 1 ? 
ATOM   1179 N  N   . SER A 1 154 ? 24.226 6.199   59.616 1.000 18.608  0 154 SER A N   1 ? 
ATOM   1180 C  CA  . SER A 1 154 ? 23.657 7.521   59.604 1.000 18.754  0 154 SER A CA  1 ? 
ATOM   1181 C  C   . SER A 1 154 ? 23.963 8.243   58.293 1.000 18.549  0 154 SER A C   1 ? 
ATOM   1182 O  O   . SER A 1 154 ? 23.085 8.844   57.696 1.000 19.176  0 154 SER A O   1 ? 
ATOM   1183 C  CB  . SER A 1 154 ? 24.128 8.299   60.832 1.000 20.031  0 154 SER A CB  1 ? 
ATOM   1184 O  OG  . SER A 1 154 ? 23.621 9.604   60.783 1.000 20.717  0 154 SER A OG  1 ? 
ATOM   1185 N  N   . LEU A 1 155 ? 25.240 8.249   57.874 1.000 17.569  0 155 LEU A N   1 ? 
ATOM   1186 C  CA  . LEU A 1 155 ? 25.609 8.915   56.634 1.000 16.502  0 155 LEU A CA  1 ? 
ATOM   1187 C  C   . LEU A 1 155 ? 24.862 8.330   55.429 1.000 17.412  0 155 LEU A C   1 ? 
ATOM   1188 O  O   . LEU A 1 155 ? 24.474 9.084   54.535 1.000 18.491  0 155 LEU A O   1 ? 
ATOM   1189 C  CB  . LEU A 1 155 ? 27.115 8.863   56.414 1.000 15.294  0 155 LEU A CB  1 ? 
ATOM   1190 C  CG  . LEU A 1 155 ? 27.982 9.578   57.457 1.000 16.328  0 155 LEU A CG  1 ? 
ATOM   1191 C  CD1 . LEU A 1 155 ? 29.453 9.267   57.191 1.000 16.241  0 155 LEU A CD1 1 ? 
ATOM   1192 C  CD2 . LEU A 1 155 ? 27.731 11.065  57.454 1.000 17.865  0 155 LEU A CD2 1 ? 
ATOM   1193 N  N   . SER A 1 156 ? 24.625 7.015   55.462 1.000 20.486  0 156 SER A N   1 ? 
ATOM   1194 C  CA  . SER A 1 156 ? 24.059 6.322   54.307 1.000 20.857  0 156 SER A CA  1 ? 
ATOM   1195 C  C   . SER A 1 156 ? 22.542 6.519   54.260 1.000 23.692  0 156 SER A C   1 ? 
ATOM   1196 O  O   . SER A 1 156 ? 21.914 6.407   53.203 1.000 23.435  0 156 SER A O   1 ? 
ATOM   1197 C  CB  . SER A 1 156 ? 24.506 4.901   54.283 1.000 20.994  0 156 SER A CB  1 ? 
ATOM   1198 O  OG  . SER A 1 156 ? 23.880 4.109   55.299 1.000 24.365  0 156 SER A OG  1 ? 
ATOM   1199 N  N   . ALA A 1 157 ? 21.935 6.806   55.415 1.000 25.606  0 157 ALA A N   1 ? 
ATOM   1200 C  CA  . ALA A 1 157 ? 20.490 6.917   55.549 1.000 28.736  0 157 ALA A CA  1 ? 
ATOM   1201 C  C   . ALA A 1 157 ? 19.996 8.307   55.179 1.000 31.299  0 157 ALA A C   1 ? 
ATOM   1202 O  O   . ALA A 1 157 ? 18.787 8.518   55.142 1.000 33.069  0 157 ALA A O   1 ? 
ATOM   1203 C  CB  . ALA A 1 157 ? 20.052 6.584   56.965 1.000 26.744  0 157 ALA A CB  1 ? 
ATOM   1204 N  N   . GLY A 1 158 ? 20.924 9.276   55.061 1.000 31.896  0 158 GLY A N   1 ? 
ATOM   1205 C  CA  . GLY A 1 158 ? 20.601 10.595  54.535 1.000 32.043  0 158 GLY A CA  1 ? 
ATOM   1206 C  C   . GLY A 1 158 ? 19.590 11.376  55.371 1.000 35.877  0 158 GLY A C   1 ? 
ATOM   1207 O  O   . GLY A 1 158 ? 18.685 12.001  54.835 1.000 43.938  0 158 GLY A O   1 ? 
ATOM   1208 N  N   . GLY A 1 159 ? 19.747 11.362  56.689 1.000 31.165  0 159 GLY A N   1 ? 
ATOM   1209 C  CA  . GLY A 1 159 ? 18.882 12.115  57.568 1.000 31.302  0 159 GLY A CA  1 ? 
ATOM   1210 C  C   . GLY A 1 159 ? 19.520 13.424  58.039 1.000 27.659  0 159 GLY A C   1 ? 
ATOM   1211 O  O   . GLY A 1 159 ? 18.877 14.184  58.757 1.000 28.645  0 159 GLY A O   1 ? 
ATOM   1212 N  N   . ARG A 1 160 ? 20.792 13.661  57.691 1.000 23.614  0 160 ARG A N   1 ? 
ATOM   1213 C  CA  . ARG A 1 160 ? 21.435 14.912  58.092 1.000 21.272  0 160 ARG A CA  1 ? 
ATOM   1214 C  C   . ARG A 1 160 ? 20.505 16.067  57.733 1.000 20.312  0 160 ARG A C   1 ? 
ATOM   1215 O  O   . ARG A 1 160 ? 19.912 16.117  56.638 1.000 21.787  0 160 ARG A O   1 ? 
ATOM   1216 C  CB  . ARG A 1 160 ? 22.803 15.065  57.412 1.000 20.158  0 160 ARG A CB  1 ? 
ATOM   1217 C  CG  . ARG A 1 160 ? 23.515 16.354  57.791 1.000 20.015  0 160 ARG A CG  1 ? 
ATOM   1218 C  CD  . ARG A 1 160 ? 24.786 16.592  56.971 1.000 18.596  0 160 ARG A CD  1 ? 
ATOM   1219 N  NE  . ARG A 1 160 ? 25.851 15.637  57.221 1.000 17.159  0 160 ARG A NE  1 ? 
ATOM   1220 C  CZ  . ARG A 1 160 ? 26.524 15.462  58.314 1.000 16.290  0 160 ARG A CZ  1 ? 
ATOM   1221 N  NH1 . ARG A 1 160 ? 26.284 16.288  59.347 1.000 16.290  0 160 ARG A NH1 1 ? 
ATOM   1222 N  NH2 . ARG A 1 160 ? 27.452 14.530  58.393 1.000 16.571  0 160 ARG A NH2 1 ? 
ATOM   1223 N  N   . ASP A 1 161 ? 20.390 17.034  58.641 1.000 20.773  0 161 ASP A N   1 ? 
ATOM   1224 C  CA  . ASP A 1 161 ? 19.769 18.308  58.328 1.000 20.440  0 161 ASP A CA  1 ? 
ATOM   1225 C  C   . ASP A 1 161 ? 20.417 18.914  57.079 1.000 20.443  0 161 ASP A C   1 ? 
ATOM   1226 O  O   . ASP A 1 161 ? 21.640 18.863  56.895 1.000 20.323  0 161 ASP A O   1 ? 
ATOM   1227 C  CB  . ASP A 1 161 ? 19.909 19.329  59.441 1.000 23.079  0 161 ASP A CB  1 ? 
ATOM   1228 C  CG  . ASP A 1 161 ? 19.333 18.956  60.792 1.000 27.566  0 161 ASP A CG  1 ? 
ATOM   1229 O  OD1 . ASP A 1 161 ? 18.552 17.976  60.851 1.000 30.132  0 161 ASP A OD1 1 ? 
ATOM   1230 O  OD2 . ASP A 1 161 ? 19.684 19.654  61.772 1.000 32.065  0 161 ASP A OD2 1 ? 
ATOM   1231 N  N   . GLU A 1 162 ? 19.584 19.478  56.196 1.000 22.917  0 162 GLU A N   1 ? 
ATOM   1232 C  CA  . GLU A 1 162 ? 20.063 20.102  54.973 1.000 26.068  0 162 GLU A CA  1 ? 
ATOM   1233 C  C   . GLU A 1 162 ? 19.862 21.617  55.050 1.000 23.481  0 162 GLU A C   1 ? 
ATOM   1234 O  O   . GLU A 1 162 ? 19.480 22.146  56.093 1.000 27.387  0 162 GLU A O   1 ? 
ATOM   1235 C  CB  . GLU A 1 162 ? 19.364 19.424  53.793 1.000 29.404  0 162 GLU A CB  1 ? 
ATOM   1236 C  CG  . GLU A 1 162 ? 19.573 17.913  53.782 1.000 30.616  0 162 GLU A CG  1 ? 
ATOM   1237 C  CD  . GLU A 1 162 ? 19.697 17.267  52.425 1.000 34.942  0 162 GLU A CD  1 ? 
ATOM   1238 O  OE1 . GLU A 1 162 ? 20.429 17.798  51.549 1.000 41.301  0 162 GLU A OE1 1 ? 
ATOM   1239 O  OE2 . GLU A 1 162 ? 19.154 16.142  52.303 1.000 37.825  0 162 GLU A OE2 1 ? 
ATOM   1240 N  N   . GLY A 1 163 ? 20.155 22.313  53.952 1.000 22.310  0 163 GLY A N   1 ? 
ATOM   1241 C  CA  . GLY A 1 163 ? 20.141 23.771  53.889 1.000 23.346  0 163 GLY A CA  1 ? 
ATOM   1242 C  C   . GLY A 1 163 ? 21.201 24.358  54.829 1.000 23.731  0 163 GLY A C   1 ? 
ATOM   1243 O  O   . GLY A 1 163 ? 22.135 23.652  55.203 1.000 21.463  0 163 GLY A O   1 ? 
ATOM   1244 N  N   . ASN A 1 164 ? 20.990 25.600  55.286 1.000 23.832  0 164 ASN A N   1 ? 
ATOM   1245 C  CA  . ASN A 1 164 ? 22.036 26.364  55.960 1.000 24.129  0 164 ASN A CA  1 ? 
ATOM   1246 C  C   . ASN A 1 164 ? 21.480 27.191  57.117 1.000 23.958  0 164 ASN A C   1 ? 
ATOM   1247 O  O   . ASN A 1 164 ? 22.149 28.135  57.546 1.000 23.634  0 164 ASN A O   1 ? 
ATOM   1248 C  CB  . ASN A 1 164 ? 22.808 27.277  55.013 1.000 24.102  0 164 ASN A CB  1 ? 
ATOM   1249 C  CG  . ASN A 1 164 ? 21.921 28.321  54.377 1.000 29.386  0 164 ASN A CG  1 ? 
ATOM   1250 O  OD1 . ASN A 1 164 ? 20.768 28.493  54.783 1.000 25.778  0 164 ASN A OD1 1 ? 
ATOM   1251 N  ND2 . ASN A 1 164 ? 22.428 28.992  53.353 1.000 35.158  0 164 ASN A ND2 1 ? 
ATOM   1252 N  N   . TYR A 1 165 ? 20.313 26.815  57.652 1.000 23.444  0 165 TYR A N   1 ? 
ATOM   1253 C  CA  . TYR A 1 165 ? 19.739 27.515  58.793 1.000 22.278  0 165 TYR A CA  1 ? 
ATOM   1254 C  C   . TYR A 1 165 ? 20.736 27.548  59.962 1.000 22.755  0 165 TYR A C   1 ? 
ATOM   1255 O  O   . TYR A 1 165 ? 21.286 26.517  60.361 1.000 21.432  0 165 TYR A O   1 ? 
ATOM   1256 C  CB  . TYR A 1 165 ? 18.436 26.843  59.233 1.000 24.704  0 165 TYR A CB  1 ? 
ATOM   1257 C  CG  . TYR A 1 165 ? 17.639 27.739  60.171 1.000 30.057  0 165 TYR A CG  1 ? 
ATOM   1258 C  CD1 . TYR A 1 165 ? 16.792 28.720  59.658 1.000 33.347  0 165 TYR A CD1 1 ? 
ATOM   1259 C  CD2 . TYR A 1 165 ? 17.774 27.656  61.552 1.000 33.034  0 165 TYR A CD2 1 ? 
ATOM   1260 C  CE1 . TYR A 1 165 ? 16.082 29.571  60.488 1.000 39.012  0 165 TYR A CE1 1 ? 
ATOM   1261 C  CE2 . TYR A 1 165 ? 17.059 28.497  62.393 1.000 36.746  0 165 TYR A CE2 1 ? 
ATOM   1262 C  CZ  . TYR A 1 165 ? 16.215 29.458  61.861 1.000 39.545  0 165 TYR A CZ  1 ? 
ATOM   1263 O  OH  . TYR A 1 165 ? 15.511 30.303  62.678 1.000 39.297  0 165 TYR A OH  1 ? 
ATOM   1264 N  N   . LEU A 1 166 ? 20.943 28.745  60.541 1.000 23.257  0 166 LEU A N   1 ? 
ATOM   1265 C  CA  . LEU A 1 166 ? 21.914 28.951  61.605 1.000 22.170  0 166 LEU A CA  1 ? 
ATOM   1266 C  C   . LEU A 1 166 ? 21.224 29.463  62.866 1.000 23.638  0 166 LEU A C   1 ? 
ATOM   1267 O  O   . LEU A 1 166 ? 20.811 30.618  62.951 1.000 26.767  0 166 LEU A O   1 ? 
ATOM   1268 C  CB  . LEU A 1 166 ? 22.991 29.894  61.082 1.000 23.355  0 166 LEU A CB  1 ? 
ATOM   1269 C  CG  . LEU A 1 166 ? 24.188 30.119  62.010 1.000 25.725  0 166 LEU A CG  1 ? 
ATOM   1270 C  CD1 . LEU A 1 166 ? 24.964 28.821  62.154 1.000 29.689  0 166 LEU A CD1 1 ? 
ATOM   1271 C  CD2 . LEU A 1 166 ? 25.034 31.263  61.480 1.000 24.514  0 166 LEU A CD2 1 ? 
ATOM   1272 N  N   . ASP A 1 167 ? 21.136 28.583  63.868 1.000 24.361  0 167 ASP A N   1 ? 
ATOM   1273 C  CA  . ASP A 1 167 ? 20.697 28.899  65.219 1.000 25.105  0 167 ASP A CA  1 ? 
ATOM   1274 C  C   . ASP A 1 167 ? 21.897 29.053  66.163 1.000 22.602  0 167 ASP A C   1 ? 
ATOM   1275 O  O   . ASP A 1 167 ? 22.490 28.048  66.551 1.000 20.538  0 167 ASP A O   1 ? 
ATOM   1276 C  CB  . ASP A 1 167 ? 19.806 27.759  65.672 1.000 29.787  0 167 ASP A CB  1 ? 
ATOM   1277 C  CG  . ASP A 1 167 ? 19.231 27.910  67.070 1.000 33.426  0 167 ASP A CG  1 ? 
ATOM   1278 O  OD1 . ASP A 1 167 ? 19.753 28.738  67.828 1.000 34.569  0 167 ASP A OD1 1 ? 
ATOM   1279 O  OD2 . ASP A 1 167 ? 18.212 27.259  67.333 1.000 46.689  0 167 ASP A OD2 1 ? 
ATOM   1280 N  N   . ASP A 1 168 ? 22.216 30.281  66.601 1.000 23.392  0 168 ASP A N   1 ? 
ATOM   1281 C  CA  . ASP A 1 168 ? 23.388 30.540  67.442 1.000 23.185  0 168 ASP A CA  1 ? 
ATOM   1282 C  C   . ASP A 1 168 ? 23.336 29.815  68.791 1.000 22.103  0 168 ASP A C   1 ? 
ATOM   1283 O  O   . ASP A 1 168 ? 24.359 29.315  69.273 1.000 20.247  0 168 ASP A O   1 ? 
ATOM   1284 C  CB  . ASP A 1 168 ? 23.631 32.031  67.635 1.000 26.567  0 168 ASP A CB  1 ? 
ATOM   1285 C  CG  . ASP A 1 168 ? 24.046 32.793  66.387 1.000 33.309  0 168 ASP A CG  1 ? 
ATOM   1286 O  OD1 . ASP A 1 168 ? 24.582 32.150  65.440 1.000 34.390  0 168 ASP A OD1 1 ? 
ATOM   1287 O  OD2 . ASP A 1 168 ? 23.866 34.031  66.383 1.000 37.954  0 168 ASP A OD2 1 ? 
ATOM   1288 N  N   . ALA A 1 169 ? 22.144 29.719  69.409 1.000 22.763  0 169 ALA A N   1 ? 
ATOM   1289 C  CA  . ALA A 1 169 ? 22.007 29.068  70.709 1.000 20.195  0 169 ALA A CA  1 ? 
ATOM   1290 C  C   . ALA A 1 169 ? 22.306 27.578  70.581 1.000 17.602  0 169 ALA A C   1 ? 
ATOM   1291 O  O   . ALA A 1 169 ? 22.942 26.977  71.456 1.000 18.858  0 169 ALA A O   1 ? 
ATOM   1292 C  CB  . ALA A 1 169 ? 20.617 29.300  71.305 1.000 23.386  0 169 ALA A CB  1 ? 
ATOM   1293 N  N   . LEU A 1 170 ? 21.896 26.983  69.461 1.000 18.029  0 170 LEU A N   1 ? 
ATOM   1294 C  CA  . LEU A 1 170 ? 22.121 25.559  69.282 1.000 19.379  0 170 LEU A CA  1 ? 
ATOM   1295 C  C   . LEU A 1 170 ? 23.601 25.309  68.992 1.000 18.223  0 170 LEU A C   1 ? 
ATOM   1296 O  O   . LEU A 1 170 ? 24.120 24.271  69.393 1.000 16.958  0 170 LEU A O   1 ? 
ATOM   1297 C  CB  . LEU A 1 170 ? 21.266 24.964  68.170 1.000 21.782  0 170 LEU A CB  1 ? 
ATOM   1298 C  CG  . LEU A 1 170 ? 21.376 23.453  67.936 1.000 27.345  0 170 LEU A CG  1 ? 
ATOM   1299 C  CD1 . LEU A 1 170 ? 21.151 22.613  69.187 1.000 31.779  0 170 LEU A CD1 1 ? 
ATOM   1300 C  CD2 . LEU A 1 170 ? 20.427 23.007  66.812 1.000 32.312  0 170 LEU A CD2 1 ? 
ATOM   1301 N  N   . VAL A 1 171 ? 24.235 26.189  68.207 1.000 17.304  0 171 VAL A N   1 ? 
ATOM   1302 C  CA  . VAL A 1 171 ? 25.671 26.115  67.946 1.000 16.653  0 171 VAL A CA  1 ? 
ATOM   1303 C  C   . VAL A 1 171 ? 26.402 26.063  69.281 1.000 16.372  0 171 VAL A C   1 ? 
ATOM   1304 O  O   . VAL A 1 171 ? 27.256 25.209  69.507 1.000 16.429  0 171 VAL A O   1 ? 
ATOM   1305 C  CB  . VAL A 1 171 ? 26.155 27.281  67.066 1.000 16.851  0 171 VAL A CB  1 ? 
ATOM   1306 C  CG1 . VAL A 1 171 ? 27.683 27.401  67.003 1.000 18.070  0 171 VAL A CG1 1 ? 
ATOM   1307 C  CG2 . VAL A 1 171 ? 25.599 27.183  65.657 1.000 18.074  0 171 VAL A CG2 1 ? 
ATOM   1308 N  N   . ARG A 1 172 ? 26.100 27.029  70.159 1.000 15.479  0 172 ARG A N   1 ? 
ATOM   1309 C  CA  . ARG A 1 172 ? 26.755 27.122  71.452 1.000 17.745  0 172 ARG A CA  1 ? 
ATOM   1310 C  C   . ARG A 1 172 ? 26.556 25.850  72.259 1.000 16.650  0 172 ARG A C   1 ? 
ATOM   1311 O  O   . ARG A 1 172 ? 27.493 25.348  72.892 1.000 18.963  0 172 ARG A O   1 ? 
ATOM   1312 C  CB  . ARG A 1 172 ? 26.311 28.351  72.252 1.000 21.002  0 172 ARG A CB  1 ? 
ATOM   1313 C  CG  . ARG A 1 172 ? 26.701 29.719  71.723 1.000 28.098  0 172 ARG A CG  1 ? 
ATOM   1314 C  CD  . ARG A 1 172 ? 26.085 30.849  72.620 1.000 33.434  0 172 ARG A CD  1 ? 
ATOM   1315 N  NE  . ARG A 1 172 ? 25.374 31.837  71.789 1.000 43.724  0 172 ARG A NE  1 ? 
ATOM   1316 C  CZ  . ARG A 1 172 ? 24.069 32.159  71.769 1.000 46.031  0 172 ARG A CZ  1 ? 
ATOM   1317 N  NH1 . ARG A 1 172 ? 23.246 31.909  72.773 1.000 46.166  0 172 ARG A NH1 1 ? 
ATOM   1318 N  NH2 . ARG A 1 172 ? 23.584 32.812  70.730 1.000 51.685  0 172 ARG A NH2 1 ? 
ATOM   1319 N  N   . GLN A 1 173 ? 25.326 25.300  72.243 1.000 17.113  0 173 GLN A N   1 ? 
ATOM   1320 C  CA  . GLN A 1 173 ? 25.019 24.130  73.039 1.000 18.582  0 173 GLN A CA  1 ? 
ATOM   1321 C  C   . GLN A 1 173 ? 25.811 22.924  72.547 1.000 17.207  0 173 GLN A C   1 ? 
ATOM   1322 O  O   . GLN A 1 173 ? 26.327 22.143  73.330 1.000 17.643  0 173 GLN A O   1 ? 
ATOM   1323 C  CB  . GLN A 1 173 ? 23.516 23.798  73.038 1.000 20.535  0 173 GLN A CB  1 ? 
ATOM   1324 C  CG  . GLN A 1 173 ? 23.168 22.702  74.043 1.000 29.025  0 173 GLN A CG  1 ? 
ATOM   1325 C  CD  . GLN A 1 173 ? 23.623 22.997  75.463 1.000 39.630  0 173 GLN A CD  1 ? 
ATOM   1326 O  OE1 . GLN A 1 173 ? 24.611 22.443  75.974 1.000 46.852  0 173 GLN A OE1 1 ? 
ATOM   1327 N  NE2 . GLN A 1 173 ? 22.904 23.897  76.121 1.000 42.205  0 173 GLN A NE2 1 ? 
ATOM   1328 N  N   . ASP A 1 174 ? 25.875 22.758  71.227 1.000 17.125  0 174 ASP A N   1 ? 
ATOM   1329 C  CA  . ASP A 1 174 ? 26.585 21.640  70.632 1.000 16.534  0 174 ASP A CA  1 ? 
ATOM   1330 C  C   . ASP A 1 174 ? 28.074 21.729  70.975 1.000 16.089  0 174 ASP A C   1 ? 
ATOM   1331 O  O   . ASP A 1 174 ? 28.676 20.726  71.353 1.000 16.379  0 174 ASP A O   1 ? 
ATOM   1332 C  CB  . ASP A 1 174 ? 26.413 21.627  69.113 1.000 16.659  0 174 ASP A CB  1 ? 
ATOM   1333 C  CG  . ASP A 1 174 ? 25.089 21.071  68.609 1.000 17.784  0 174 ASP A CG  1 ? 
ATOM   1334 O  OD1 . ASP A 1 174 ? 24.388 20.454  69.404 1.000 19.834  0 174 ASP A OD1 1 ? 
ATOM   1335 O  OD2 . ASP A 1 174 ? 24.791 21.277  67.447 1.000 19.146  0 174 ASP A OD2 1 ? 
ATOM   1336 N  N   . ALA A 1 175 ? 28.650 22.933  70.885 1.000 16.159  0 175 ALA A N   1 ? 
ATOM   1337 C  CA  . ALA A 1 175 ? 30.061 23.077  71.235 1.000 17.259  0 175 ALA A CA  1 ? 
ATOM   1338 C  C   . ALA A 1 175 ? 30.315 22.739  72.705 1.000 16.522  0 175 ALA A C   1 ? 
ATOM   1339 O  O   . ALA A 1 175 ? 31.309 22.068  73.029 1.000 16.834  0 175 ALA A O   1 ? 
ATOM   1340 C  CB  . ALA A 1 175 ? 30.533 24.468  70.926 1.000 16.878  0 175 ALA A CB  1 ? 
ATOM   1341 N  N   . GLN A 1 176 ? 29.434 23.244  73.600 1.000 18.710  0 176 GLN A N   1 ? 
ATOM   1342 C  CA  . GLN A 1 176 ? 29.508 22.979  75.035 1.000 19.860  0 176 GLN A CA  1 ? 
ATOM   1343 C  C   . GLN A 1 176 ? 29.411 21.484  75.338 1.000 21.160  0 176 GLN A C   1 ? 
ATOM   1344 O  O   . GLN A 1 176 ? 30.168 20.940  76.152 1.000 21.154  0 176 GLN A O   1 ? 
ATOM   1345 C  CB  . GLN A 1 176 ? 28.406 23.796  75.733 1.000 23.677  0 176 GLN A CB  1 ? 
ATOM   1346 C  CG  . GLN A 1 176 ? 28.410 23.693  77.252 1.000 30.879  0 176 GLN A CG  1 ? 
ATOM   1347 C  CD  . GLN A 1 176 ? 29.699 24.199  77.867 1.000 38.066  0 176 GLN A CD  1 ? 
ATOM   1348 O  OE1 . GLN A 1 176 ? 30.377 25.076  77.314 1.000 42.475  0 176 GLN A OE1 1 ? 
ATOM   1349 N  NE2 . GLN A 1 176 ? 30.021 23.680  79.042 1.000 41.300  0 176 GLN A NE2 1 ? 
ATOM   1350 N  N   . ASP A 1 177 ? 28.486 20.801  74.671 1.000 18.762  0 177 ASP A N   1 ? 
ATOM   1351 C  CA  . ASP A 1 177 ? 28.330 19.364  74.834 1.000 21.424  0 177 ASP A CA  1 ? 
ATOM   1352 C  C   . ASP A 1 177 ? 29.579 18.607  74.394 1.000 20.529  0 177 ASP A C   1 ? 
ATOM   1353 O  O   . ASP A 1 177 ? 30.003 17.655  75.069 1.000 21.670  0 177 ASP A O   1 ? 
ATOM   1354 C  CB  . ASP A 1 177 ? 27.134 18.860  74.054 1.000 22.405  0 177 ASP A CB  1 ? 
ATOM   1355 C  CG  . ASP A 1 177 ? 25.795 19.286  74.631 1.000 27.833  0 177 ASP A CG  1 ? 
ATOM   1356 O  OD1 . ASP A 1 177 ? 25.784 19.875  75.724 1.000 29.519  0 177 ASP A OD1 1 ? 
ATOM   1357 O  OD2 . ASP A 1 177 ? 24.808 19.072  73.940 1.000 31.976  0 177 ASP A OD2 1 ? 
ATOM   1358 N  N   . LEU A 1 178 ? 30.221 19.043  73.314 1.000 19.040  0 178 LEU A N   1 ? 
ATOM   1359 C  CA  . LEU A 1 178 ? 31.458 18.380  72.869 1.000 17.578  0 178 LEU A CA  1 ? 
ATOM   1360 C  C   . LEU A 1 178 ? 32.594 18.656  73.846 1.000 20.923  0 178 LEU A C   1 ? 
ATOM   1361 O  O   . LEU A 1 178 ? 33.432 17.777  74.091 1.000 21.945  0 178 LEU A O   1 ? 
ATOM   1362 C  CB  . LEU A 1 178 ? 31.813 18.766  71.441 1.000 18.744  0 178 LEU A CB  1 ? 
ATOM   1363 C  CG  . LEU A 1 178 ? 30.806 18.334  70.370 1.000 20.474  0 178 LEU A CG  1 ? 
ATOM   1364 C  CD1 . LEU A 1 178 ? 31.184 18.795  69.009 1.000 21.433  0 178 LEU A CD1 1 ? 
ATOM   1365 C  CD2 . LEU A 1 178 ? 30.617 16.816  70.408 1.000 23.647  0 178 LEU A CD2 1 ? 
ATOM   1366 N  N   . TYR A 1 179 ? 32.641 19.879  74.400 1.000 19.473  0 179 TYR A N   1 ? 
ATOM   1367 C  CA  . TYR A 1 179 ? 33.625 20.196  75.425 1.000 21.208  0 179 TYR A CA  1 ? 
ATOM   1368 C  C   . TYR A 1 179 ? 33.444 19.254  76.627 1.000 21.510  0 179 TYR A C   1 ? 
ATOM   1369 O  O   . TYR A 1 179 ? 34.391 18.628  77.122 1.000 21.703  0 179 TYR A O   1 ? 
ATOM   1370 C  CB  . TYR A 1 179 ? 33.476 21.670  75.782 1.000 21.745  0 179 TYR A CB  1 ? 
ATOM   1371 C  CG  . TYR A 1 179 ? 34.336 22.169  76.940 1.000 22.864  0 179 TYR A CG  1 ? 
ATOM   1372 C  CD1 . TYR A 1 179 ? 34.007 21.891  78.259 1.000 26.715  0 179 TYR A CD1 1 ? 
ATOM   1373 C  CD2 . TYR A 1 179 ? 35.526 22.819  76.697 1.000 24.211  0 179 TYR A CD2 1 ? 
ATOM   1374 C  CE1 . TYR A 1 179 ? 34.806 22.311  79.320 1.000 30.462  0 179 TYR A CE1 1 ? 
ATOM   1375 C  CE2 . TYR A 1 179 ? 36.331 23.251  77.734 1.000 22.049  0 179 TYR A CE2 1 ? 
ATOM   1376 C  CZ  . TYR A 1 179 ? 35.973 23.004  79.046 1.000 24.792  0 179 TYR A CZ  1 ? 
ATOM   1377 O  OH  . TYR A 1 179 ? 36.777 23.456  80.063 1.000 27.285  0 179 TYR A OH  1 ? 
ATOM   1378 N  N   . GLU A 1 180 ? 32.213 19.156  77.123 1.000 22.418  0 180 GLU A N   1 ? 
ATOM   1379 C  CA  . GLU A 1 180 ? 31.928 18.325  78.287 1.000 26.272  0 180 GLU A CA  1 ? 
ATOM   1380 C  C   . GLU A 1 180 ? 32.316 16.872  78.030 1.000 28.031  0 180 GLU A C   1 ? 
ATOM   1381 O  O   . GLU A 1 180 ? 32.848 16.217  78.926 1.000 31.987  0 180 GLU A O   1 ? 
ATOM   1382 C  CB  . GLU A 1 180 ? 30.459 18.504  78.684 1.000 28.357  0 180 GLU A CB  1 ? 
ATOM   1383 C  CG  . GLU A 1 180 ? 30.219 19.896  79.261 1.000 35.072  0 180 GLU A CG  1 ? 
ATOM   1384 C  CD  . GLU A 1 180 ? 28.761 20.215  79.576 1.000 44.955  0 180 GLU A CD  1 ? 
ATOM   1385 O  OE1 . GLU A 1 180 ? 27.909 19.301  79.490 1.000 53.325  0 180 GLU A OE1 1 ? 
ATOM   1386 O  OE2 . GLU A 1 180 ? 28.470 21.394  79.874 1.000 48.813  0 180 GLU A OE2 1 ? 
ATOM   1387 N  N   . ALA A 1 181 ? 32.103 16.394  76.808 1.000 26.121  0 181 ALA A N   1 ? 
ATOM   1388 C  CA  . ALA A 1 181 ? 32.453 15.035  76.436 1.000 31.977  0 181 ALA A CA  1 ? 
ATOM   1389 C  C   . ALA A 1 181 ? 33.965 14.828  76.527 1.000 37.170  0 181 ALA A C   1 ? 
ATOM   1390 O  O   . ALA A 1 181 ? 34.410 13.698  76.702 1.000 39.057  0 181 ALA A O   1 ? 
ATOM   1391 C  CB  . ALA A 1 181 ? 31.950 14.733  75.047 1.000 34.773  0 181 ALA A CB  1 ? 
ATOM   1392 N  N   . GLY A 1 182 ? 34.742 15.916  76.388 1.000 30.608  0 182 GLY A N   1 ? 
ATOM   1393 C  CA  . GLY A 1 182 ? 36.193 15.851  76.474 1.000 30.624  0 182 GLY A CA  1 ? 
ATOM   1394 C  C   . GLY A 1 182 ? 36.735 15.891  77.903 1.000 32.100  0 182 GLY A C   1 ? 
ATOM   1395 O  O   . GLY A 1 182 ? 37.932 15.737  78.095 1.000 31.025  0 182 GLY A O   1 ? 
ATOM   1396 N  N   . GLU A 1 183 ? 35.892 16.131  78.910 1.000 38.269  0 183 GLU A N   1 ? 
ATOM   1397 C  CA  . GLU A 1 183 ? 36.360 16.229  80.293 1.000 40.690  0 183 GLU A CA  1 ? 
ATOM   1398 C  C   . GLU A 1 183 ? 36.484 14.853  80.955 1.000 51.485  0 183 GLU A C   1 ? 
ATOM   1399 O  O   . GLU A 1 183 ? 37.191 14.712  81.950 1.000 53.435  0 183 GLU A O   1 ? 
ATOM   1400 C  CB  . GLU A 1 183 ? 35.421 17.103  81.120 1.000 41.342  0 183 GLU A CB  1 ? 
ATOM   1401 C  CG  . GLU A 1 183 ? 35.530 18.576  80.758 1.000 43.314  0 183 GLU A CG  1 ? 
ATOM   1402 C  CD  . GLU A 1 183 ? 34.607 19.482  81.540 1.000 49.454  0 183 GLU A CD  1 ? 
ATOM   1403 O  OE1 . GLU A 1 183 ? 33.367 19.363  81.393 1.000 45.134  0 183 GLU A OE1 1 ? 
ATOM   1404 O  OE2 . GLU A 1 183 ? 35.151 20.323  82.290 1.000 57.138  0 183 GLU A OE2 1 ? 
ATOM   1405 N  N   . LYS A 1 184 ? 35.824 13.840  80.382 1.000 56.339  0 184 LYS A N   1 ? 
ATOM   1406 C  CA  . LYS A 1 184 ? 35.624 12.550  81.025 1.000 67.127  0 184 LYS A CA  1 ? 
ATOM   1407 C  C   . LYS A 1 184 ? 36.960 11.907  81.404 1.000 75.646  0 184 LYS A C   1 ? 
ATOM   1408 O  O   . LYS A 1 184 ? 37.948 12.020  80.674 1.000 62.704  0 184 LYS A O   1 ? 
ATOM   1409 C  CB  . LYS A 1 184 ? 34.745 11.701  80.097 1.000 70.092  0 184 LYS A CB  1 ? 
ATOM   1410 C  CG  . LYS A 1 184 ? 33.408 12.385  79.795 1.000 72.909  0 184 LYS A CG  1 ? 
ATOM   1411 C  CD  . LYS A 1 184 ? 32.289 11.519  79.234 1.000 78.033  0 184 LYS A CD  1 ? 
ATOM   1412 C  CE  . LYS A 1 184 ? 30.938 12.131  79.470 1.000 82.098  0 184 LYS A CE  1 ? 
ATOM   1413 N  NZ  . LYS A 1 184 ? 29.864 11.140  79.604 1.000 84.481  0 184 LYS A NZ  1 ? 
ATOM   1414 N  N   . LYS A 1 185 ? 36.937 11.232  82.567 1.000 88.725  0 185 LYS A N   1 ? 
ATOM   1415 C  CA  . LYS A 1 185 ? 38.074 10.576  83.202 1.000 95.892  0 185 LYS A CA  1 ? 
ATOM   1416 C  C   . LYS A 1 185 ? 38.009 9.072   82.938 1.000 98.318  0 185 LYS A C   1 ? 
ATOM   1417 O  O   . LYS A 1 185 ? 38.398 8.262   83.784 1.000 91.313  0 185 LYS A O   1 ? 
ATOM   1418 C  CB  . LYS A 1 185 ? 37.944 10.836  84.712 1.000 102.049 0 185 LYS A CB  1 ? 
ATOM   1419 C  CG  . LYS A 1 185 ? 39.043 10.330  85.654 1.000 101.239 0 185 LYS A CG  1 ? 
ATOM   1420 C  CD  . LYS A 1 185 ? 38.649 10.425  87.124 1.000 98.851  0 185 LYS A CD  1 ? 
ATOM   1421 C  CE  . LYS A 1 185 ? 39.756 10.060  88.059 1.000 96.305  0 185 LYS A CE  1 ? 
ATOM   1422 N  NZ  . LYS A 1 185 ? 39.245 9.844   89.416 1.000 94.993  0 185 LYS A NZ  1 ? 
ATOM   1423 N  N   . TRP A 1 186 ? 37.488 8.698   81.764 1.000 100.255 0 186 TRP A N   1 ? 
ATOM   1424 C  CA  . TRP A 1 186 ? 36.917 7.371   81.608 1.000 100.806 0 186 TRP A CA  1 ? 
ATOM   1425 C  C   . TRP A 1 186 ? 36.670 6.974   80.151 1.000 94.719  0 186 TRP A C   1 ? 
ATOM   1426 O  O   . TRP A 1 186 ? 36.312 5.825   79.889 1.000 91.091  0 186 TRP A O   1 ? 
ATOM   1427 C  CB  . TRP A 1 186 ? 35.626 7.271   82.445 1.000 113.655 0 186 TRP A CB  1 ? 
ATOM   1428 C  CG  . TRP A 1 186 ? 34.444 8.128   82.041 1.000 118.593 0 186 TRP A CG  1 ? 
ATOM   1429 C  CD1 . TRP A 1 186 ? 33.624 7.918   80.968 1.000 122.465 0 186 TRP A CD1 1 ? 
ATOM   1430 C  CD2 . TRP A 1 186 ? 33.863 9.245   82.766 1.000 110.424 0 186 TRP A CD2 1 ? 
ATOM   1431 N  NE1 . TRP A 1 186 ? 32.616 8.846   80.942 1.000 118.478 0 186 TRP A NE1 1 ? 
ATOM   1432 C  CE2 . TRP A 1 186 ? 32.726 9.667   82.035 1.000 111.004 0 186 TRP A CE2 1 ? 
ATOM   1433 C  CE3 . TRP A 1 186 ? 34.189 9.935   83.942 1.000 96.699  0 186 TRP A CE3 1 ? 
ATOM   1434 C  CZ2 . TRP A 1 186 ? 31.929 10.738  82.443 1.000 98.196  0 186 TRP A CZ2 1 ? 
ATOM   1435 C  CZ3 . TRP A 1 186 ? 33.395 10.989  84.346 1.000 89.630  0 186 TRP A CZ3 1 ? 
ATOM   1436 C  CH2 . TRP A 1 186 ? 32.276 11.378  83.612 1.000 91.391  0 186 TRP A CH2 1 ? 
ATOM   1437 N  N   . GLY A 1 187 ? 36.857 7.898   79.202 1.000 82.516  0 187 GLY A N   1 ? 
ATOM   1438 C  CA  . GLY A 1 187 ? 36.414 7.662   77.841 1.000 82.589  0 187 GLY A CA  1 ? 
ATOM   1439 C  C   . GLY A 1 187 ? 35.233 8.564   77.481 1.000 83.116  0 187 GLY A C   1 ? 
ATOM   1440 O  O   . GLY A 1 187 ? 34.157 8.468   78.068 1.000 94.296  0 187 GLY A O   1 ? 
ATOM   1441 N  N   . THR A 1 188 ? 35.499 9.457   76.521 1.000 68.991  0 188 THR A N   1 ? 
ATOM   1442 C  CA  . THR A 1 188 ? 34.566 10.348  75.840 1.000 54.493  0 188 THR A CA  1 ? 
ATOM   1443 C  C   . THR A 1 188 ? 33.103 9.890   75.827 1.000 44.854  0 188 THR A C   1 ? 
ATOM   1444 O  O   . THR A 1 188 ? 32.810 8.697   75.904 1.000 42.798  0 188 THR A O   1 ? 
ATOM   1445 C  CB  . THR A 1 188 ? 35.124 10.402  74.421 1.000 56.837  0 188 THR A CB  1 ? 
ATOM   1446 O  OG1 . THR A 1 188 ? 36.524 10.191  74.620 1.000 53.413  0 188 THR A OG1 1 ? 
ATOM   1447 C  CG2 . THR A 1 188 ? 34.764 11.699  73.725 1.000 56.571  0 188 THR A CG2 1 ? 
ATOM   1448 N  N   . ASP A 1 189 ? 32.178 10.850  75.635 1.000 38.008  0 189 ASP A N   1 ? 
ATOM   1449 C  CA  . ASP A 1 189 ? 30.799 10.514  75.312 1.000 34.700  0 189 ASP A CA  1 ? 
ATOM   1450 C  C   . ASP A 1 189 ? 30.638 10.416  73.797 1.000 32.321  0 189 ASP A C   1 ? 
ATOM   1451 O  O   . ASP A 1 189 ? 30.352 11.419  73.143 1.000 30.482  0 189 ASP A O   1 ? 
ATOM   1452 C  CB  . ASP A 1 189 ? 29.802 11.493  75.911 1.000 36.816  0 189 ASP A CB  1 ? 
ATOM   1453 C  CG  . ASP A 1 189 ? 28.350 11.176  75.572 1.000 42.438  0 189 ASP A CG  1 ? 
ATOM   1454 O  OD1 . ASP A 1 189 ? 28.107 10.212  74.792 1.000 46.693  0 189 ASP A OD1 1 ? 
ATOM   1455 O  OD2 . ASP A 1 189 ? 27.473 11.905  76.053 1.000 42.733  0 189 ASP A OD2 1 ? 
ATOM   1456 N  N   . GLU A 1 190 ? 30.799 9.200   73.249 1.000 31.654  0 190 GLU A N   1 ? 
ATOM   1457 C  CA  . GLU A 1 190 ? 30.926 9.025   71.811 1.000 30.887  0 190 GLU A CA  1 ? 
ATOM   1458 C  C   . GLU A 1 190 ? 29.604 9.281   71.099 1.000 29.900  0 190 GLU A C   1 ? 
ATOM   1459 O  O   . GLU A 1 190 ? 29.591 9.661   69.928 1.000 26.630  0 190 GLU A O   1 ? 
ATOM   1460 C  CB  . GLU A 1 190 ? 31.509 7.656   71.469 1.000 33.488  0 190 GLU A CB  1 ? 
ATOM   1461 C  CG  . GLU A 1 190 ? 32.915 7.455   72.028 1.000 33.826  0 190 GLU A CG  1 ? 
ATOM   1462 C  CD  . GLU A 1 190 ? 33.647 6.245   71.478 1.000 38.382  0 190 GLU A CD  1 ? 
ATOM   1463 O  OE1 . GLU A 1 190 ? 32.960 5.297   71.054 1.000 38.545  0 190 GLU A OE1 1 ? 
ATOM   1464 O  OE2 . GLU A 1 190 ? 34.891 6.283   71.407 1.000 40.164  0 190 GLU A OE2 1 ? 
ATOM   1465 N  N   . VAL A 1 191 ? 28.475 9.063   71.775 1.000 26.224  0 191 VAL A N   1 ? 
ATOM   1466 C  CA  . VAL A 1 191 ? 27.194 9.293   71.142 1.000 27.756  0 191 VAL A CA  1 ? 
ATOM   1467 C  C   . VAL A 1 191 ? 27.082 10.778  70.775 1.000 24.672  0 191 VAL A C   1 ? 
ATOM   1468 O  O   . VAL A 1 191 ? 26.495 11.124  69.763 1.000 23.699  0 191 VAL A O   1 ? 
ATOM   1469 C  CB  . VAL A 1 191 ? 26.034 8.803   72.034 1.000 31.983  0 191 VAL A CB  1 ? 
ATOM   1470 C  CG1 . VAL A 1 191 ? 24.672 9.020   71.381 1.000 34.633  0 191 VAL A CG1 1 ? 
ATOM   1471 C  CG2 . VAL A 1 191 ? 26.199 7.329   72.408 1.000 35.337  0 191 VAL A CG2 1 ? 
ATOM   1472 N  N   . LYS A 1 192 ? 27.630 11.673  71.602 1.000 25.960  0 192 LYS A N   1 ? 
ATOM   1473 C  CA  . LYS A 1 192 ? 27.481 13.097  71.341 1.000 23.059  0 192 LYS A CA  1 ? 
ATOM   1474 C  C   . LYS A 1 192 ? 28.221 13.483  70.069 1.000 21.771  0 192 LYS A C   1 ? 
ATOM   1475 O  O   . LYS A 1 192 ? 27.677 14.255  69.289 1.000 20.268  0 192 LYS A O   1 ? 
ATOM   1476 C  CB  . LYS A 1 192 ? 28.002 14.024  72.450 1.000 29.797  0 192 LYS A CB  1 ? 
ATOM   1477 C  CG  . LYS A 1 192 ? 27.068 14.237  73.621 1.000 38.644  0 192 LYS A CG  1 ? 
ATOM   1478 C  CD  . LYS A 1 192 ? 27.842 14.957  74.718 1.000 45.618  0 192 LYS A CD  1 ? 
ATOM   1479 C  CE  . LYS A 1 192 ? 27.139 15.293  76.006 1.000 49.819  0 192 LYS A CE  1 ? 
ATOM   1480 N  NZ  . LYS A 1 192 ? 28.100 16.054  76.823 1.000 46.304  0 192 LYS A NZ  1 ? 
ATOM   1481 N  N   . PHE A 1 193 ? 29.434 12.966  69.865 1.000 20.089  0 193 PHE A N   1 ? 
ATOM   1482 C  CA  . PHE A 1 193 ? 30.120 13.190  68.607 1.000 21.426  0 193 PHE A CA  1 ? 
ATOM   1483 C  C   . PHE A 1 193 ? 29.291 12.684  67.435 1.000 19.876  0 193 PHE A C   1 ? 
ATOM   1484 O  O   . PHE A 1 193 ? 29.145 13.359  66.422 1.000 20.656  0 193 PHE A O   1 ? 
ATOM   1485 C  CB  . PHE A 1 193 ? 31.506 12.549  68.616 1.000 22.016  0 193 PHE A CB  1 ? 
ATOM   1486 C  CG  . PHE A 1 193 ? 32.492 13.396  69.387 1.000 25.225  0 193 PHE A CG  1 ? 
ATOM   1487 C  CD1 . PHE A 1 193 ? 33.235 14.362  68.733 1.000 23.194  0 193 PHE A CD1 1 ? 
ATOM   1488 C  CD2 . PHE A 1 193 ? 32.682 13.228  70.757 1.000 30.911  0 193 PHE A CD2 1 ? 
ATOM   1489 C  CE1 . PHE A 1 193 ? 34.151 15.150  69.413 1.000 28.277  0 193 PHE A CE1 1 ? 
ATOM   1490 C  CE2 . PHE A 1 193 ? 33.604 14.018  71.436 1.000 31.420  0 193 PHE A CE2 1 ? 
ATOM   1491 C  CZ  . PHE A 1 193 ? 34.327 14.987  70.765 1.000 30.118  0 193 PHE A CZ  1 ? 
ATOM   1492 N  N   . LEU A 1 194 ? 28.770 11.462  67.545 1.000 22.005  0 194 LEU A N   1 ? 
ATOM   1493 C  CA  . LEU A 1 194 ? 27.890 10.892  66.539 1.000 22.949  0 194 LEU A CA  1 ? 
ATOM   1494 C  C   . LEU A 1 194 ? 26.729 11.825  66.198 1.000 21.104  0 194 LEU A C   1 ? 
ATOM   1495 O  O   . LEU A 1 194 ? 26.530 12.161  65.029 1.000 19.928  0 194 LEU A O   1 ? 
ATOM   1496 C  CB  . LEU A 1 194 ? 27.369 9.514   66.987 1.000 26.333  0 194 LEU A CB  1 ? 
ATOM   1497 C  CG  . LEU A 1 194 ? 26.182 8.946   66.198 1.000 27.806  0 194 LEU A CG  1 ? 
ATOM   1498 C  CD1 . LEU A 1 194 ? 26.656 8.473   64.844 1.000 31.177  0 194 LEU A CD1 1 ? 
ATOM   1499 C  CD2 . LEU A 1 194 ? 25.460 7.820   66.951 1.000 30.322  0 194 LEU A CD2 1 ? 
ATOM   1500 N  N   . THR A 1 195 ? 25.965 12.292  67.198 1.000 19.698  0 195 THR A N   1 ? 
ATOM   1501 C  CA  . THR A 1 195 ? 24.760 13.069  66.989 1.000 21.035  0 195 THR A CA  1 ? 
ATOM   1502 C  C   . THR A 1 195 ? 25.089 14.402  66.300 1.000 20.865  0 195 THR A C   1 ? 
ATOM   1503 O  O   . THR A 1 195 ? 24.490 14.806  65.292 1.000 19.754  0 195 THR A O   1 ? 
ATOM   1504 C  CB  . THR A 1 195 ? 24.062 13.289  68.343 1.000 26.788  0 195 THR A CB  1 ? 
ATOM   1505 O  OG1 . THR A 1 195 ? 23.738 12.009  68.895 1.000 26.430  0 195 THR A OG1 1 ? 
ATOM   1506 C  CG2 . THR A 1 195 ? 22.799 14.126  68.189 1.000 28.702  0 195 THR A CG2 1 ? 
ATOM   1507 N  N   . VAL A 1 196 ? 26.055 15.147  66.858 1.000 18.369  0 196 VAL A N   1 ? 
ATOM   1508 C  CA  . VAL A 1 196 ? 26.366 16.455  66.334 1.000 16.458  0 196 VAL A CA  1 ? 
ATOM   1509 C  C   . VAL A 1 196 ? 26.902 16.305  64.920 1.000 16.485  0 196 VAL A C   1 ? 
ATOM   1510 O  O   . VAL A 1 196 ? 26.437 17.017  64.033 1.000 16.201  0 196 VAL A O   1 ? 
ATOM   1511 C  CB  . VAL A 1 196 ? 27.372 17.188  67.234 1.000 17.973  0 196 VAL A CB  1 ? 
ATOM   1512 C  CG1 . VAL A 1 196 ? 27.915 18.463  66.601 1.000 20.202  0 196 VAL A CG1 1 ? 
ATOM   1513 C  CG2 . VAL A 1 196 ? 26.765 17.477  68.607 1.000 19.313  0 196 VAL A CG2 1 ? 
ATOM   1514 N  N   . LEU A 1 197 ? 27.934 15.469  64.740 1.000 15.559  0 197 LEU A N   1 ? 
ATOM   1515 C  CA  . LEU A 1 197 ? 28.640 15.439  63.457 1.000 15.955  0 197 LEU A CA  1 ? 
ATOM   1516 C  C   . LEU A 1 197 ? 27.823 14.785  62.341 1.000 15.582  0 197 LEU A C   1 ? 
ATOM   1517 O  O   . LEU A 1 197 ? 28.068 15.101  61.177 1.000 15.740  0 197 LEU A O   1 ? 
ATOM   1518 C  CB  . LEU A 1 197 ? 30.004 14.774  63.608 1.000 17.463  0 197 LEU A CB  1 ? 
ATOM   1519 C  CG  . LEU A 1 197 ? 31.007 15.589  64.428 1.000 19.343  0 197 LEU A CG  1 ? 
ATOM   1520 C  CD1 . LEU A 1 197 ? 32.320 14.856  64.670 1.000 19.482  0 197 LEU A CD1 1 ? 
ATOM   1521 C  CD2 . LEU A 1 197 ? 31.304 16.893  63.735 1.000 21.793  0 197 LEU A CD2 1 ? 
ATOM   1522 N  N   . CYS A 1 198 ? 26.901 13.880  62.676 1.000 16.547  0 198 CYS A N   1 ? 
ATOM   1523 C  CA  . CYS A 1 198 ? 26.053 13.280  61.660 1.000 16.426  0 198 CYS A CA  1 ? 
ATOM   1524 C  C   . CYS A 1 198 ? 24.695 13.972  61.456 1.000 17.792  0 198 CYS A C   1 ? 
ATOM   1525 O  O   . CYS A 1 198 ? 24.048 13.727  60.422 1.000 19.765  0 198 CYS A O   1 ? 
ATOM   1526 C  CB  . CYS A 1 198 ? 25.820 11.805  61.961 1.000 18.558  0 198 CYS A CB  1 ? 
ATOM   1527 S  SG  . CYS A 1 198 ? 27.322 10.797  61.866 1.000 21.606  0 198 CYS A SG  1 ? 
ATOM   1528 N  N   . SER A 1 199 ? 24.188 14.796  62.371 1.000 16.640  0 199 SER A N   1 ? 
ATOM   1529 C  CA  . SER A 1 199 ? 22.839 15.332  62.252 1.000 16.723  0 199 SER A CA  1 ? 
ATOM   1530 C  C   . SER A 1 199 ? 22.792 16.751  61.704 1.000 17.598  0 199 SER A C   1 ? 
ATOM   1531 O  O   . SER A 1 199 ? 21.780 17.163  61.135 1.000 17.736  0 199 SER A O   1 ? 
ATOM   1532 C  CB  . SER A 1 199 ? 22.104 15.366  63.580 1.000 19.959  0 199 SER A CB  1 ? 
ATOM   1533 O  OG  . SER A 1 199 ? 22.050 14.077  64.133 1.000 24.174  0 199 SER A OG  1 ? 
ATOM   1534 N  N   . ARG A 1 200 ? 23.793 17.582  62.039 1.000 15.919  0 200 ARG A N   1 ? 
ATOM   1535 C  CA  . ARG A 1 200 ? 23.672 19.009  61.784 1.000 16.572  0 200 ARG A CA  1 ? 
ATOM   1536 C  C   . ARG A 1 200 ? 24.045 19.395  60.353 1.000 15.166  0 200 ARG A C   1 ? 
ATOM   1537 O  O   . ARG A 1 200 ? 24.879 18.743  59.716 1.000 16.310  0 200 ARG A O   1 ? 
ATOM   1538 C  CB  . ARG A 1 200 ? 24.533 19.799  62.780 1.000 15.727  0 200 ARG A CB  1 ? 
ATOM   1539 C  CG  . ARG A 1 200 ? 24.250 19.513  64.244 1.000 17.015  0 200 ARG A CG  1 ? 
ATOM   1540 C  CD  . ARG A 1 200 ? 22.877 19.964  64.635 1.000 19.239  0 200 ARG A CD  1 ? 
ATOM   1541 N  NE  . ARG A 1 200 ? 22.795 19.854  66.099 1.000 19.573  0 200 ARG A NE  1 ? 
ATOM   1542 C  CZ  . ARG A 1 200 ? 22.211 18.866  66.726 1.000 25.399  0 200 ARG A CZ  1 ? 
ATOM   1543 N  NH1 . ARG A 1 200 ? 21.376 18.051  66.083 1.000 26.857  0 200 ARG A NH1 1 ? 
ATOM   1544 N  NH2 . ARG A 1 200 ? 22.437 18.717  68.016 1.000 27.723  0 200 ARG A NH2 1 ? 
ATOM   1545 N  N   . ASN A 1 201 ? 23.476 20.513  59.852 1.000 16.535  0 201 ASN A N   1 ? 
ATOM   1546 C  CA  . ASN A 1 201 ? 23.845 21.038  58.537 1.000 17.089  0 201 ASN A CA  1 ? 
ATOM   1547 C  C   . ASN A 1 201 ? 25.249 21.642  58.545 1.000 17.716  0 201 ASN A C   1 ? 
ATOM   1548 O  O   . ASN A 1 201 ? 25.804 21.884  59.617 1.000 15.368  0 201 ASN A O   1 ? 
ATOM   1549 C  CB  . ASN A 1 201 ? 22.808 21.993  57.961 1.000 17.370  0 201 ASN A CB  1 ? 
ATOM   1550 C  CG  . ASN A 1 201 ? 22.783 23.370  58.571 1.000 19.629  0 201 ASN A CG  1 ? 
ATOM   1551 O  OD1 . ASN A 1 201 ? 23.810 24.055  58.621 1.000 20.381  0 201 ASN A OD1 1 ? 
ATOM   1552 N  ND2 . ASN A 1 201 ? 21.624 23.830  59.020 1.000 21.641  0 201 ASN A ND2 1 ? 
ATOM   1553 N  N   . ARG A 1 202 ? 25.860 21.768  57.356 1.000 17.778  0 202 ARG A N   1 ? 
ATOM   1554 C  CA  . ARG A 1 202 ? 27.248 22.187  57.188 1.000 17.055  0 202 ARG A CA  1 ? 
ATOM   1555 C  C   . ARG A 1 202 ? 27.528 23.565  57.790 1.000 17.616  0 202 ARG A C   1 ? 
ATOM   1556 O  O   . ARG A 1 202 ? 28.500 23.743  58.530 1.000 16.123  0 202 ARG A O   1 ? 
ATOM   1557 C  CB  . ARG A 1 202 ? 27.607 22.217  55.696 1.000 17.892  0 202 ARG A CB  1 ? 
ATOM   1558 C  CG  . ARG A 1 202 ? 29.056 22.603  55.459 1.000 20.158  0 202 ARG A CG  1 ? 
ATOM   1559 C  CD  . ARG A 1 202 ? 29.411 22.353  54.007 1.000 23.926  0 202 ARG A CD  1 ? 
ATOM   1560 N  NE  . ARG A 1 202 ? 30.807 22.767  53.817 1.000 25.785  0 202 ARG A NE  1 ? 
ATOM   1561 C  CZ  . ARG A 1 202 ? 31.226 23.896  53.241 1.000 31.425  0 202 ARG A CZ  1 ? 
ATOM   1562 N  NH1 . ARG A 1 202 ? 30.337 24.760  52.786 1.000 36.046  0 202 ARG A NH1 1 ? 
ATOM   1563 N  NH2 . ARG A 1 202 ? 32.518 24.155  53.129 1.000 32.795  0 202 ARG A NH2 1 ? 
ATOM   1564 N  N   . ASN A 1 203 ? 26.700 24.563  57.455 1.000 16.458  0 203 ASN A N   1 ? 
ATOM   1565 C  CA  . ASN A 1 203 ? 26.828 25.906  58.013 1.000 16.137  0 203 ASN A CA  1 ? 
ATOM   1566 C  C   . ASN A 1 203 ? 26.841 25.848  59.549 1.000 15.189  0 203 ASN A C   1 ? 
ATOM   1567 O  O   . ASN A 1 203 ? 27.726 26.403  60.217 1.000 15.344  0 203 ASN A O   1 ? 
ATOM   1568 C  CB  . ASN A 1 203 ? 25.750 26.813  57.451 1.000 16.431  0 203 ASN A CB  1 ? 
ATOM   1569 C  CG  . ASN A 1 203 ? 25.967 28.285  57.752 1.000 19.184  0 203 ASN A CG  1 ? 
ATOM   1570 O  OD1 . ASN A 1 203 ? 27.113 28.744  57.841 1.000 19.910  0 203 ASN A OD1 1 ? 
ATOM   1571 N  ND2 . ASN A 1 203 ? 24.882 29.023  57.940 1.000 22.918  0 203 ASN A ND2 1 ? 
ATOM   1572 N  N   . HIS A 1 204 ? 25.916 25.086  60.118 1.000 13.927  0 204 HIS A N   1 ? 
ATOM   1573 C  CA  . HIS A 1 204 ? 25.856 24.924  61.560 1.000 14.768  0 204 HIS A CA  1 ? 
ATOM   1574 C  C   . HIS A 1 204 ? 27.167 24.312  62.052 1.000 14.162  0 204 HIS A C   1 ? 
ATOM   1575 O  O   . HIS A 1 204 ? 27.752 24.766  63.046 1.000 15.418  0 204 HIS A O   1 ? 
ATOM   1576 C  CB  . HIS A 1 204 ? 24.681 24.020  61.904 1.000 16.111  0 204 HIS A CB  1 ? 
ATOM   1577 C  CG  . HIS A 1 204 ? 24.486 23.860  63.353 1.000 15.682  0 204 HIS A CG  1 ? 
ATOM   1578 N  ND1 . HIS A 1 204 ? 25.151 22.967  64.174 1.000 19.092  0 204 HIS A ND1 1 ? 
ATOM   1579 C  CD2 . HIS A 1 204 ? 23.537 24.451  64.109 1.000 17.713  0 204 HIS A CD2 1 ? 
ATOM   1580 C  CE1 . HIS A 1 204 ? 24.655 23.088  65.405 1.000 14.819  0 204 HIS A CE1 1 ? 
ATOM   1581 N  NE2 . HIS A 1 204 ? 23.684 23.985  65.382 1.000 20.267  0 204 HIS A NE2 1 ? 
ATOM   1582 N  N   . LEU A 1 205 ? 27.602 23.231  61.424 1.000 14.931  0 205 LEU A N   1 ? 
ATOM   1583 C  CA  . LEU A 1 205 ? 28.814 22.567  61.894 1.000 15.613  0 205 LEU A CA  1 ? 
ATOM   1584 C  C   . LEU A 1 205 ? 30.017 23.469  61.795 1.000 13.846  0 205 LEU A C   1 ? 
ATOM   1585 O  O   . LEU A 1 205 ? 30.901 23.398  62.667 1.000 14.769  0 205 LEU A O   1 ? 
ATOM   1586 C  CB  . LEU A 1 205 ? 29.076 21.259  61.166 1.000 15.713  0 205 LEU A CB  1 ? 
ATOM   1587 C  CG  . LEU A 1 205 ? 28.160 20.129  61.612 1.000 17.462  0 205 LEU A CG  1 ? 
ATOM   1588 C  CD1 . LEU A 1 205 ? 28.425 18.907  60.731 1.000 17.215  0 205 LEU A CD1 1 ? 
ATOM   1589 C  CD2 . LEU A 1 205 ? 28.366 19.806  63.072 1.000 17.507  0 205 LEU A CD2 1 ? 
ATOM   1590 N  N   . LEU A 1 206 ? 30.167 24.235  60.721 1.000 14.984  0 206 LEU A N   1 ? 
ATOM   1591 C  CA  . LEU A 1 206 ? 31.337 25.113  60.635 1.000 16.843  0 206 LEU A CA  1 ? 
ATOM   1592 C  C   . LEU A 1 206 ? 31.350 26.084  61.820 1.000 14.692  0 206 LEU A C   1 ? 
ATOM   1593 O  O   . LEU A 1 206 ? 32.420 26.357  62.377 1.000 14.879  0 206 LEU A O   1 ? 
ATOM   1594 C  CB  . LEU A 1 206 ? 31.421 25.854  59.303 1.000 17.495  0 206 LEU A CB  1 ? 
ATOM   1595 C  CG  . LEU A 1 206 ? 31.588 24.919  58.097 1.000 17.724  0 206 LEU A CG  1 ? 
ATOM   1596 C  CD1 . LEU A 1 206 ? 31.451 25.707  56.794 1.000 21.058  0 206 LEU A CD1 1 ? 
ATOM   1597 C  CD2 . LEU A 1 206 ? 32.915 24.216  58.140 1.000 20.844  0 206 LEU A CD2 1 ? 
ATOM   1598 N  N   . HIS A 1 207 ? 30.175 26.558  62.223 1.000 13.529  0 207 HIS A N   1 ? 
ATOM   1599 C  CA  . HIS A 1 207 ? 30.037 27.422  63.403 1.000 14.639  0 207 HIS A CA  1 ? 
ATOM   1600 C  C   . HIS A 1 207 ? 30.339 26.672  64.694 1.000 14.765  0 207 HIS A C   1 ? 
ATOM   1601 O  O   . HIS A 1 207 ? 30.951 27.232  65.618 1.000 15.403  0 207 HIS A O   1 ? 
ATOM   1602 C  CB  . HIS A 1 207 ? 28.655 28.096  63.397 1.000 14.703  0 207 HIS A CB  1 ? 
ATOM   1603 C  CG  . HIS A 1 207 ? 28.532 29.124  62.346 1.000 15.987  0 207 HIS A CG  1 ? 
ATOM   1604 N  ND1 . HIS A 1 207 ? 28.597 30.481  62.578 1.000 20.749  0 207 HIS A ND1 1 ? 
ATOM   1605 C  CD2 . HIS A 1 207 ? 28.392 28.977  61.012 1.000 14.923  0 207 HIS A CD2 1 ? 
ATOM   1606 C  CE1 . HIS A 1 207 ? 28.467 31.120  61.415 1.000 18.411  0 207 HIS A CE1 1 ? 
ATOM   1607 N  NE2 . HIS A 1 207 ? 28.326 30.231  60.448 1.000 21.472  0 207 HIS A NE2 1 ? 
ATOM   1608 N  N   . VAL A 1 208 ? 29.926 25.401  64.806 1.000 13.755  0 208 VAL A N   1 ? 
ATOM   1609 C  CA  . VAL A 1 208 ? 30.297 24.614  65.973 1.000 13.664  0 208 VAL A CA  1 ? 
ATOM   1610 C  C   . VAL A 1 208 ? 31.811 24.457  66.027 1.000 13.078  0 208 VAL A C   1 ? 
ATOM   1611 O  O   . VAL A 1 208 ? 32.381 24.548  67.107 1.000 14.401  0 208 VAL A O   1 ? 
ATOM   1612 C  CB  . VAL A 1 208 ? 29.599 23.250  65.951 1.000 13.609  0 208 VAL A CB  1 ? 
ATOM   1613 C  CG1 . VAL A 1 208 ? 30.196 22.323  66.986 1.000 15.317  0 208 VAL A CG1 1 ? 
ATOM   1614 C  CG2 . VAL A 1 208 ? 28.085 23.378  66.100 1.000 14.310  0 208 VAL A CG2 1 ? 
ATOM   1615 N  N   . PHE A 1 209 ? 32.484 24.187  64.910 1.000 14.413  0 209 PHE A N   1 ? 
ATOM   1616 C  CA  . PHE A 1 209 ? 33.935 24.023  64.959 1.000 14.045  0 209 PHE A CA  1 ? 
ATOM   1617 C  C   . PHE A 1 209 ? 34.590 25.290  65.516 1.000 14.893  0 209 PHE A C   1 ? 
ATOM   1618 O  O   . PHE A 1 209 ? 35.516 25.207  66.340 1.000 14.268  0 209 PHE A O   1 ? 
ATOM   1619 C  CB  . PHE A 1 209 ? 34.507 23.622  63.590 1.000 14.745  0 209 PHE A CB  1 ? 
ATOM   1620 C  CG  . PHE A 1 209 ? 33.932 22.360  62.943 1.000 15.017  0 209 PHE A CG  1 ? 
ATOM   1621 C  CD1 . PHE A 1 209 ? 33.289 21.356  63.652 1.000 15.903  0 209 PHE A CD1 1 ? 
ATOM   1622 C  CD2 . PHE A 1 209 ? 34.007 22.241  61.575 1.000 17.434  0 209 PHE A CD2 1 ? 
ATOM   1623 C  CE1 . PHE A 1 209 ? 32.753 20.256  62.992 1.000 17.037  0 209 PHE A CE1 1 ? 
ATOM   1624 C  CE2 . PHE A 1 209 ? 33.482 21.137  60.928 1.000 17.746  0 209 PHE A CE2 1 ? 
ATOM   1625 C  CZ  . PHE A 1 209 ? 32.896 20.136  61.641 1.000 16.463  0 209 PHE A CZ  1 ? 
ATOM   1626 N  N   . ASP A 1 210 ? 34.090 26.446  65.081 1.000 14.796  0 210 ASP A N   1 ? 
ATOM   1627 C  CA  . ASP A 1 210 ? 34.675 27.708  65.476 1.000 16.044  0 210 ASP A CA  1 ? 
ATOM   1628 C  C   . ASP A 1 210 ? 34.453 27.921  66.956 1.000 15.010  0 210 ASP A C   1 ? 
ATOM   1629 O  O   . ASP A 1 210 ? 35.396 28.311  67.671 1.000 15.346  0 210 ASP A O   1 ? 
ATOM   1630 C  CB  . ASP A 1 210 ? 34.153 28.882  64.666 1.000 18.142  0 210 ASP A CB  1 ? 
ATOM   1631 C  CG  . ASP A 1 210 ? 34.590 28.939  63.217 1.000 23.436  0 210 ASP A CG  1 ? 
ATOM   1632 O  OD1 . ASP A 1 210 ? 35.523 28.184  62.832 1.000 26.713  0 210 ASP A OD1 1 ? 
ATOM   1633 O  OD2 . ASP A 1 210 ? 33.915 29.670  62.468 1.000 26.911  0 210 ASP A OD2 1 ? 
ATOM   1634 N  N   . GLU A 1 211 ? 33.210 27.709  67.413 1.000 14.712  0 211 GLU A N   1 ? 
ATOM   1635 C  CA  . GLU A 1 211 ? 32.881 27.916  68.809 1.000 15.671  0 211 GLU A CA  1 ? 
ATOM   1636 C  C   . GLU A 1 211 ? 33.651 26.946  69.691 1.000 15.899  0 211 GLU A C   1 ? 
ATOM   1637 O  O   . GLU A 1 211 ? 34.062 27.284  70.795 1.000 15.297  0 211 GLU A O   1 ? 
ATOM   1638 C  CB  . GLU A 1 211 ? 31.368 27.788  68.955 1.000 16.993  0 211 GLU A CB  1 ? 
ATOM   1639 C  CG  . GLU A 1 211 ? 30.892 27.982  70.384 1.000 18.043  0 211 GLU A CG  1 ? 
ATOM   1640 C  CD  . GLU A 1 211 ? 30.998 29.388  70.956 1.000 21.726  0 211 GLU A CD  1 ? 
ATOM   1641 O  OE1 . GLU A 1 211 ? 31.394 30.375  70.313 1.000 23.874  0 211 GLU A OE1 1 ? 
ATOM   1642 O  OE2 . GLU A 1 211 ? 30.648 29.427  72.143 1.000 24.807  0 211 GLU A OE2 1 ? 
ATOM   1643 N  N   . TYR A 1 212 ? 33.805 25.691  69.248 1.000 13.255  0 212 TYR A N   1 ? 
ATOM   1644 C  CA  . TYR A 1 212 ? 34.526 24.679  69.992 1.000 13.817  0 212 TYR A CA  1 ? 
ATOM   1645 C  C   . TYR A 1 212 ? 35.969 25.118  70.225 1.000 14.319  0 212 TYR A C   1 ? 
ATOM   1646 O  O   . TYR A 1 212 ? 36.508 24.942  71.336 1.000 15.327  0 212 TYR A O   1 ? 
ATOM   1647 C  CB  . TYR A 1 212 ? 34.483 23.322  69.265 1.000 13.606  0 212 TYR A CB  1 ? 
ATOM   1648 C  CG  . TYR A 1 212 ? 35.185 22.252  70.082 1.000 13.005  0 212 TYR A CG  1 ? 
ATOM   1649 C  CD1 . TYR A 1 212 ? 34.558 21.630  71.141 1.000 13.770  0 212 TYR A CD1 1 ? 
ATOM   1650 C  CD2 . TYR A 1 212 ? 36.507 21.920  69.800 1.000 14.397  0 212 TYR A CD2 1 ? 
ATOM   1651 C  CE1 . TYR A 1 212 ? 35.219 20.694  71.901 1.000 14.925  0 212 TYR A CE1 1 ? 
ATOM   1652 C  CE2 . TYR A 1 212 ? 37.190 20.967  70.555 1.000 13.413  0 212 TYR A CE2 1 ? 
ATOM   1653 C  CZ  . TYR A 1 212 ? 36.539 20.381  71.624 1.000 14.286  0 212 TYR A CZ  1 ? 
ATOM   1654 O  OH  . TYR A 1 212 ? 37.194 19.452  72.427 1.000 17.171  0 212 TYR A OH  1 ? 
ATOM   1655 N  N   . LYS A 1 213 ? 36.625 25.634  69.190 1.000 15.401  0 213 LYS A N   1 ? 
ATOM   1656 C  CA  . LYS A 1 213 ? 37.987 26.142  69.352 1.000 16.009  0 213 LYS A CA  1 ? 
ATOM   1657 C  C   . LYS A 1 213 ? 38.012 27.292  70.366 1.000 17.028  0 213 LYS A C   1 ? 
ATOM   1658 O  O   . LYS A 1 213 ? 38.915 27.363  71.200 1.000 17.794  0 213 LYS A O   1 ? 
ATOM   1659 C  CB  . LYS A 1 213 ? 38.506 26.614  67.995 1.000 18.672  0 213 LYS A CB  1 ? 
ATOM   1660 C  CG  . LYS A 1 213 ? 39.918 27.225  67.921 1.000 21.896  0 213 LYS A CG  1 ? 
ATOM   1661 C  CD  . LYS A 1 213 ? 41.059 26.367  68.430 1.000 25.255  0 213 LYS A CD  1 ? 
ATOM   1662 C  CE  . LYS A 1 213 ? 42.383 27.113  68.380 1.000 33.006  0 213 LYS A CE  1 ? 
ATOM   1663 N  NZ  . LYS A 1 213 ? 43.031 26.813  67.094 1.000 35.358  0 213 LYS A NZ  1 ? 
ATOM   1664 N  N   . ARG A 1 214 ? 37.014 28.168  70.317 1.000 16.359  0 214 ARG A N   1 ? 
ATOM   1665 C  CA  . ARG A 1 214 ? 36.948 29.310  71.222 1.000 19.787  0 214 ARG A CA  1 ? 
ATOM   1666 C  C   . ARG A 1 214 ? 36.876 28.857  72.679 1.000 18.568  0 214 ARG A C   1 ? 
ATOM   1667 O  O   . ARG A 1 214 ? 37.572 29.425  73.551 1.000 20.847  0 214 ARG A O   1 ? 
ATOM   1668 C  CB  . ARG A 1 214 ? 35.741 30.191  70.860 1.000 22.132  0 214 ARG A CB  1 ? 
ATOM   1669 C  CG  . ARG A 1 214 ? 35.706 31.533  71.593 1.000 28.868  0 214 ARG A CG  1 ? 
ATOM   1670 C  CD  . ARG A 1 214 ? 34.441 32.354  71.319 1.000 31.322  0 214 ARG A CD  1 ? 
ATOM   1671 N  NE  . ARG A 1 214 ? 33.256 31.895  72.054 1.000 32.309  0 214 ARG A NE  1 ? 
ATOM   1672 C  CZ  . ARG A 1 214 ? 33.075 31.869  73.361 1.000 34.829  0 214 ARG A CZ  1 ? 
ATOM   1673 N  NH1 . ARG A 1 214 ? 33.988 32.363  74.191 1.000 40.981  0 214 ARG A NH1 1 ? 
ATOM   1674 N  NH2 . ARG A 1 214 ? 31.958 31.361  73.843 1.000 31.281  0 214 ARG A NH2 1 ? 
ATOM   1675 N  N   . ILE A 1 215 ? 36.064 27.854  72.999 1.000 16.806  0 215 ILE A N   1 ? 
ATOM   1676 C  CA  . ILE A 1 215 ? 35.831 27.471  74.381 1.000 16.660  0 215 ILE A CA  1 ? 
ATOM   1677 C  C   . ILE A 1 215 ? 36.857 26.446  74.868 1.000 17.431  0 215 ILE A C   1 ? 
ATOM   1678 O  O   . ILE A 1 215 ? 37.143 26.396  76.062 1.000 20.220  0 215 ILE A O   1 ? 
ATOM   1679 C  CB  . ILE A 1 215 ? 34.388 27.002  74.619 1.000 18.592  0 215 ILE A CB  1 ? 
ATOM   1680 C  CG1 . ILE A 1 215 ? 34.087 25.692  73.876 1.000 20.104  0 215 ILE A CG1 1 ? 
ATOM   1681 C  CG2 . ILE A 1 215 ? 33.443 28.118  74.214 1.000 19.765  0 215 ILE A CG2 1 ? 
ATOM   1682 C  CD1 . ILE A 1 215 ? 32.763 25.059  74.253 1.000 21.373  0 215 ILE A CD1 1 ? 
ATOM   1683 N  N   . SER A 1 216 ? 37.412 25.595  73.990 1.000 15.566  0 216 SER A N   1 ? 
ATOM   1684 C  CA  . SER A 1 216 ? 38.308 24.526  74.418 1.000 16.276  0 216 SER A CA  1 ? 
ATOM   1685 C  C   . SER A 1 216 ? 39.784 24.875  74.221 1.000 15.413  0 216 SER A C   1 ? 
ATOM   1686 O  O   . SER A 1 216 ? 40.657 24.221  74.814 1.000 16.879  0 216 SER A O   1 ? 
ATOM   1687 C  CB  . SER A 1 216 ? 38.028 23.232  73.658 1.000 17.330  0 216 SER A CB  1 ? 
ATOM   1688 O  OG  . SER A 1 216 ? 38.543 23.344  72.348 1.000 16.418  0 216 SER A OG  1 ? 
ATOM   1689 N  N   . GLN A 1 217 ? 40.058 25.798  73.300 1.000 17.405  0 217 GLN A N   1 ? 
ATOM   1690 C  CA  . GLN A 1 217 ? 41.394 26.184  72.880 1.000 17.296  0 217 GLN A CA  1 ? 
ATOM   1691 C  C   . GLN A 1 217 ? 42.034 25.114  71.987 1.000 20.323  0 217 GLN A C   1 ? 
ATOM   1692 O  O   . GLN A 1 217 ? 43.225 25.163  71.717 1.000 22.535  0 217 GLN A O   1 ? 
ATOM   1693 C  CB  . GLN A 1 217 ? 42.285 26.576  74.072 1.000 19.908  0 217 GLN A CB  1 ? 
ATOM   1694 C  CG  . GLN A 1 217 ? 41.790 27.799  74.844 1.000 22.075  0 217 GLN A CG  1 ? 
ATOM   1695 C  CD  . GLN A 1 217 ? 41.635 29.044  73.997 1.000 24.753  0 217 GLN A CD  1 ? 
ATOM   1696 O  OE1 . GLN A 1 217 ? 40.524 29.456  73.626 1.000 30.552  0 217 GLN A OE1 1 ? 
ATOM   1697 N  NE2 . GLN A 1 217 ? 42.742 29.656  73.639 1.000 24.022  0 217 GLN A NE2 1 ? 
ATOM   1698 N  N   . LYS A 1 218 ? 41.257 24.135  71.533 1.000 18.000  0 218 LYS A N   1 ? 
ATOM   1699 C  CA  . LYS A 1 218 ? 41.756 23.091  70.648 1.000 20.990  0 218 LYS A CA  1 ? 
ATOM   1700 C  C   . LYS A 1 218 ? 40.852 23.012  69.435 1.000 18.977  0 218 LYS A C   1 ? 
ATOM   1701 O  O   . LYS A 1 218 ? 39.662 23.319  69.515 1.000 17.769  0 218 LYS A O   1 ? 
ATOM   1702 C  CB  . LYS A 1 218 ? 41.665 21.746  71.350 1.000 23.139  0 218 LYS A CB  1 ? 
ATOM   1703 C  CG  . LYS A 1 218 ? 42.792 21.571  72.378 1.000 29.838  0 218 LYS A CG  1 ? 
ATOM   1704 C  CD  . LYS A 1 218 ? 42.311 20.991  73.686 1.000 38.302  0 218 LYS A CD  1 ? 
ATOM   1705 C  CE  . LYS A 1 218 ? 43.461 20.804  74.621 1.000 42.708  0 218 LYS A CE  1 ? 
ATOM   1706 N  NZ  . LYS A 1 218 ? 42.981 20.096  75.807 1.000 49.171  0 218 LYS A NZ  1 ? 
ATOM   1707 N  N   . ASP A 1 219 ? 41.464 22.703  68.288 1.000 17.109  0 219 ASP A N   1 ? 
ATOM   1708 C  CA  . ASP A 1 219 ? 40.665 22.308  67.138 1.000 18.366  0 219 ASP A CA  1 ? 
ATOM   1709 C  C   . ASP A 1 219 ? 39.890 21.027  67.445 1.000 16.981  0 219 ASP A C   1 ? 
ATOM   1710 O  O   . ASP A 1 219 ? 40.392 20.129  68.097 1.000 15.274  0 219 ASP A O   1 ? 
ATOM   1711 C  CB  . ASP A 1 219 ? 41.513 22.082  65.905 1.000 23.246  0 219 ASP A CB  1 ? 
ATOM   1712 C  CG  . ASP A 1 219 ? 42.498 23.181  65.537 1.000 33.196  0 219 ASP A CG  1 ? 
ATOM   1713 O  OD1 . ASP A 1 219 ? 42.066 24.336  65.346 1.000 39.210  0 219 ASP A OD1 1 ? 
ATOM   1714 O  OD2 . ASP A 1 219 ? 43.709 22.850  65.431 1.000 42.951  0 219 ASP A OD2 1 ? 
ATOM   1715 N  N   . ILE A 1 220 ? 38.682 20.891  66.879 1.000 14.852  0 220 ILE A N   1 ? 
ATOM   1716 C  CA  . ILE A 1 220 ? 37.913 19.683  67.096 1.000 16.423  0 220 ILE A CA  1 ? 
ATOM   1717 C  C   . ILE A 1 220 ? 38.681 18.443  66.608 1.000 16.282  0 220 ILE A C   1 ? 
ATOM   1718 O  O   . ILE A 1 220 ? 38.561 17.408  67.223 1.000 16.487  0 220 ILE A O   1 ? 
ATOM   1719 C  CB  . ILE A 1 220 ? 36.510 19.796  66.481 1.000 19.269  0 220 ILE A CB  1 ? 
ATOM   1720 C  CG1 . ILE A 1 220 ? 35.591 18.699  67.003 1.000 21.231  0 220 ILE A CG1 1 ? 
ATOM   1721 C  CG2 . ILE A 1 220 ? 36.591 19.828  64.968 1.000 19.212  0 220 ILE A CG2 1 ? 
ATOM   1722 C  CD1 . ILE A 1 220 ? 34.163 18.865  66.568 1.000 26.316  0 220 ILE A CD1 1 ? 
ATOM   1723 N  N   . GLU A 1 221 ? 39.482 18.577  65.546 1.000 17.406  0 221 GLU A N   1 ? 
ATOM   1724 C  CA  . GLU A 1 221 ? 40.303 17.450  65.090 1.000 18.276  0 221 GLU A CA  1 ? 
ATOM   1725 C  C   . GLU A 1 221 ? 41.259 16.933  66.161 1.000 17.021  0 221 GLU A C   1 ? 
ATOM   1726 O  O   . GLU A 1 221 ? 41.429 15.723  66.352 1.000 19.759  0 221 GLU A O   1 ? 
ATOM   1727 C  CB  . GLU A 1 221 ? 41.058 17.730  63.793 1.000 19.971  0 221 GLU A CB  1 ? 
ATOM   1728 C  CG  . GLU A 1 221 ? 40.144 17.968  62.603 1.000 23.462  0 221 GLU A CG  1 ? 
ATOM   1729 C  CD  . GLU A 1 221 ? 39.902 19.435  62.381 1.000 28.176  0 221 GLU A CD  1 ? 
ATOM   1730 O  OE1 . GLU A 1 221 ? 39.700 20.223  63.376 1.000 29.385  0 221 GLU A OE1 1 ? 
ATOM   1731 O  OE2 . GLU A 1 221 ? 39.869 19.717  61.172 1.000 29.458  0 221 GLU A OE2 1 ? 
ATOM   1732 N  N   . GLN A 1 222 ? 41.856 17.858  66.915 1.000 18.047  0 222 GLN A N   1 ? 
ATOM   1733 C  CA  . GLN A 1 222 ? 42.780 17.465  67.964 1.000 19.394  0 222 GLN A CA  1 ? 
ATOM   1734 C  C   . GLN A 1 222 ? 42.080 16.689  69.058 1.000 19.274  0 222 GLN A C   1 ? 
ATOM   1735 O  O   . GLN A 1 222 ? 42.572 15.681  69.563 1.000 20.306  0 222 GLN A O   1 ? 
ATOM   1736 C  CB  . GLN A 1 222 ? 43.304 18.735  68.620 1.000 21.377  0 222 GLN A CB  1 ? 
ATOM   1737 C  CG  . GLN A 1 222 ? 44.326 19.469  67.781 1.000 25.403  0 222 GLN A CG  1 ? 
ATOM   1738 C  CD  . GLN A 1 222 ? 44.902 20.602  68.599 1.000 30.471  0 222 GLN A CD  1 ? 
ATOM   1739 O  OE1 . GLN A 1 222 ? 45.920 20.427  69.293 1.000 36.790  0 222 GLN A OE1 1 ? 
ATOM   1740 N  NE2 . GLN A 1 222 ? 44.234 21.743  68.573 1.000 21.606  0 222 GLN A NE2 1 ? 
ATOM   1741 N  N   . SER A 1 223 ? 40.894 17.184  69.450 1.000 18.781  0 223 SER A N   1 ? 
ATOM   1742 C  CA  . SER A 1 223 ? 40.104 16.509  70.454 1.000 18.882  0 223 SER A CA  1 ? 
ATOM   1743 C  C   . SER A 1 223 ? 39.596 15.150  69.955 1.000 20.288  0 223 SER A C   1 ? 
ATOM   1744 O  O   . SER A 1 223 ? 39.600 14.197  70.711 1.000 20.226  0 223 SER A O   1 ? 
ATOM   1745 C  CB  . SER A 1 223 ? 38.977 17.399  70.914 1.000 21.367  0 223 SER A CB  1 ? 
ATOM   1746 O  OG  . SER A 1 223 ? 39.507 18.516  71.627 1.000 20.693  0 223 SER A OG  1 ? 
ATOM   1747 N  N   . ILE A 1 224 ? 39.244 15.038  68.659 1.000 18.068  0 224 ILE A N   1 ? 
ATOM   1748 C  CA  . ILE A 1 224 ? 38.796 13.751  68.143 1.000 18.046  0 224 ILE A CA  1 ? 
ATOM   1749 C  C   . ILE A 1 224 ? 39.934 12.733  68.248 1.000 18.100  0 224 ILE A C   1 ? 
ATOM   1750 O  O   . ILE A 1 224 ? 39.730 11.577  68.645 1.000 18.598  0 224 ILE A O   1 ? 
ATOM   1751 C  CB  . ILE A 1 224 ? 38.241 13.876  66.711 1.000 17.287  0 224 ILE A CB  1 ? 
ATOM   1752 C  CG1 . ILE A 1 224 ? 36.895 14.581  66.718 1.000 17.866  0 224 ILE A CG1 1 ? 
ATOM   1753 C  CG2 . ILE A 1 224 ? 38.129 12.489  66.039 1.000 17.913  0 224 ILE A CG2 1 ? 
ATOM   1754 C  CD1 . ILE A 1 224 ? 36.411 15.133  65.384 1.000 18.012  0 224 ILE A CD1 1 ? 
ATOM   1755 N  N   . LYS A 1 225 ? 41.140 13.178  67.879 1.000 18.865  0 225 LYS A N   1 ? 
ATOM   1756 C  CA  . LYS A 1 225 ? 42.320 12.327  67.915 1.000 22.145  0 225 LYS A CA  1 ? 
ATOM   1757 C  C   . LYS A 1 225 ? 42.699 11.901  69.326 1.000 25.265  0 225 LYS A C   1 ? 
ATOM   1758 O  O   . LYS A 1 225 ? 43.204 10.798  69.480 1.000 27.395  0 225 LYS A O   1 ? 
ATOM   1759 C  CB  . LYS A 1 225 ? 43.520 13.008  67.252 1.000 24.386  0 225 LYS A CB  1 ? 
ATOM   1760 C  CG  . LYS A 1 225 ? 43.390 13.275  65.778 1.000 26.785  0 225 LYS A CG  1 ? 
ATOM   1761 C  CD  . LYS A 1 225 ? 44.610 14.023  65.251 1.000 28.736  0 225 LYS A CD  1 ? 
ATOM   1762 C  CE  . LYS A 1 225 ? 44.519 14.494  63.854 1.000 33.250  0 225 LYS A CE  1 ? 
ATOM   1763 N  NZ  . LYS A 1 225 ? 44.483 13.362  62.922 1.000 40.805  0 225 LYS A NZ  1 ? 
ATOM   1764 N  N   . SER A 1 226 ? 42.504 12.763  70.338 1.000 25.544  0 226 SER A N   1 ? 
ATOM   1765 C  CA  . SER A 1 226 ? 42.787 12.420  71.731 1.000 26.779  0 226 SER A CA  1 ? 
ATOM   1766 C  C   . SER A 1 226 ? 41.739 11.519  72.365 1.000 27.489  0 226 SER A C   1 ? 
ATOM   1767 O  O   . SER A 1 226 ? 42.025 10.834  73.334 1.000 29.905  0 226 SER A O   1 ? 
ATOM   1768 C  CB  . SER A 1 226 ? 42.881 13.672  72.591 1.000 27.973  0 226 SER A CB  1 ? 
ATOM   1769 O  OG  . SER A 1 226 ? 43.960 14.472  72.163 1.000 35.243  0 226 SER A OG  1 ? 
ATOM   1770 N  N   . GLU A 1 227 ? 40.496 11.598  71.912 1.000 23.767  0 227 GLU A N   1 ? 
ATOM   1771 C  CA  . GLU A 1 227 ? 39.374 11.087  72.677 1.000 24.160  0 227 GLU A CA  1 ? 
ATOM   1772 C  C   . GLU A 1 227 ? 38.742 9.838   72.059 1.000 22.314  0 227 GLU A C   1 ? 
ATOM   1773 O  O   . GLU A 1 227 ? 37.881 9.217   72.676 1.000 23.468  0 227 GLU A O   1 ? 
ATOM   1774 C  CB  . GLU A 1 227 ? 38.331 12.195  72.772 1.000 28.094  0 227 GLU A CB  1 ? 
ATOM   1775 C  CG  . GLU A 1 227 ? 38.860 13.412  73.522 1.000 30.009  0 227 GLU A CG  1 ? 
ATOM   1776 C  CD  . GLU A 1 227 ? 37.913 14.589  73.579 1.000 34.797  0 227 GLU A CD  1 ? 
ATOM   1777 O  OE1 . GLU A 1 227 ? 36.696 14.373  73.493 1.000 33.616  0 227 GLU A OE1 1 ? 
ATOM   1778 O  OE2 . GLU A 1 227 ? 38.422 15.723  73.743 1.000 41.868  0 227 GLU A OE2 1 ? 
ATOM   1779 N  N   . THR A 1 228 ? 39.110 9.528   70.814 1.000 23.958  0 228 THR A N   1 ? 
ATOM   1780 C  CA  . THR A 1 228 ? 38.526 8.405   70.093 1.000 23.553  0 228 THR A CA  1 ? 
ATOM   1781 C  C   . THR A 1 228 ? 39.638 7.674   69.360 1.000 23.510  0 228 THR A C   1 ? 
ATOM   1782 O  O   . THR A 1 228 ? 40.762 8.164   69.250 1.000 25.081  0 228 THR A O   1 ? 
ATOM   1783 C  CB  . THR A 1 228 ? 37.420 8.827   69.119 1.000 23.034  0 228 THR A CB  1 ? 
ATOM   1784 O  OG1 . THR A 1 228 ? 38.041 9.561   68.063 1.000 22.466  0 228 THR A OG1 1 ? 
ATOM   1785 C  CG2 . THR A 1 228 ? 36.318 9.631   69.797 1.000 24.156  0 228 THR A CG2 1 ? 
ATOM   1786 N  N   . SER A 1 229 ? 39.303 6.471   68.874 1.000 24.555  0 229 SER A N   1 ? 
ATOM   1787 C  CA  . SER A 1 229 ? 40.297 5.646   68.203 1.000 24.716  0 229 SER A CA  1 ? 
ATOM   1788 C  C   . SER A 1 229 ? 39.639 4.819   67.098 1.000 24.223  0 229 SER A C   1 ? 
ATOM   1789 O  O   . SER A 1 229 ? 38.412 4.781   66.971 1.000 22.167  0 229 SER A O   1 ? 
ATOM   1790 C  CB  . SER A 1 229 ? 41.026 4.756   69.202 1.000 28.065  0 229 SER A CB  1 ? 
ATOM   1791 O  OG  . SER A 1 229 ? 40.160 3.729   69.677 1.000 31.445  0 229 SER A OG  1 ? 
ATOM   1792 N  N   . GLY A 1 230 ? 40.502 4.192   66.290 1.000 23.078  0 230 GLY A N   1 ? 
ATOM   1793 C  CA  . GLY A 1 230 ? 40.063 3.193   65.324 1.000 26.042  0 230 GLY A CA  1 ? 
ATOM   1794 C  C   . GLY A 1 230 ? 39.277 3.806   64.168 1.000 23.410  0 230 GLY A C   1 ? 
ATOM   1795 O  O   . GLY A 1 230 ? 39.436 4.980   63.852 1.000 22.333  0 230 GLY A O   1 ? 
ATOM   1796 N  N   . SER A 1 231 ? 38.423 2.987   63.550 1.000 23.212  0 231 SER A N   1 ? 
ATOM   1797 C  CA  . SER A 1 231 ? 37.650 3.427   62.403 1.000 22.136  0 231 SER A CA  1 ? 
ATOM   1798 C  C   . SER A 1 231 ? 36.677 4.544   62.776 1.000 19.107  0 231 SER A C   1 ? 
ATOM   1799 O  O   . SER A 1 231 ? 36.344 5.375   61.938 1.000 16.958  0 231 SER A O   1 ? 
ATOM   1800 C  CB  . SER A 1 231 ? 36.911 2.284   61.764 1.000 24.466  0 231 SER A CB  1 ? 
ATOM   1801 O  OG  . SER A 1 231 ? 37.806 1.538   60.937 1.000 28.124  0 231 SER A OG  1 ? 
ATOM   1802 N  N   . PHE A 1 232 ? 36.151 4.509   64.007 1.000 18.295  0 232 PHE A N   1 ? 
ATOM   1803 C  CA  . PHE A 1 232 ? 35.241 5.554   64.458 1.000 19.439  0 232 PHE A CA  1 ? 
ATOM   1804 C  C   . PHE A 1 232 ? 35.936 6.923   64.412 1.000 19.832  0 232 PHE A C   1 ? 
ATOM   1805 O  O   . PHE A 1 232 ? 35.434 7.904   63.830 1.000 17.205  0 232 PHE A O   1 ? 
ATOM   1806 C  CB  . PHE A 1 232 ? 34.761 5.160   65.862 1.000 18.987  0 232 PHE A CB  1 ? 
ATOM   1807 C  CG  . PHE A 1 232 ? 33.860 6.188   66.528 1.000 20.027  0 232 PHE A CG  1 ? 
ATOM   1808 C  CD1 . PHE A 1 232 ? 32.669 6.596   65.942 1.000 18.680  0 232 PHE A CD1 1 ? 
ATOM   1809 C  CD2 . PHE A 1 232 ? 34.238 6.786   67.734 1.000 21.568  0 232 PHE A CD2 1 ? 
ATOM   1810 C  CE1 . PHE A 1 232 ? 31.848 7.525   66.556 1.000 19.527  0 232 PHE A CE1 1 ? 
ATOM   1811 C  CE2 . PHE A 1 232 ? 33.429 7.740   68.328 1.000 22.892  0 232 PHE A CE2 1 ? 
ATOM   1812 C  CZ  . PHE A 1 232 ? 32.228 8.093   67.750 1.000 21.386  0 232 PHE A CZ  1 ? 
ATOM   1813 N  N   . GLU A 1 233 ? 37.149 6.994   64.981 1.000 17.847  0 233 GLU A N   1 ? 
ATOM   1814 C  CA  . GLU A 1 233 ? 37.961 8.200   64.900 1.000 18.433  0 233 GLU A CA  1 ? 
ATOM   1815 C  C   . GLU A 1 233 ? 38.134 8.646   63.450 1.000 18.456  0 233 GLU A C   1 ? 
ATOM   1816 O  O   . GLU A 1 233 ? 37.972 9.810   63.097 1.000 16.285  0 233 GLU A O   1 ? 
ATOM   1817 C  CB  . GLU A 1 233 ? 39.318 7.911   65.541 1.000 18.544  0 233 GLU A CB  1 ? 
ATOM   1818 C  CG  . GLU A 1 233 ? 40.269 9.097   65.451 1.000 20.739  0 233 GLU A CG  1 ? 
ATOM   1819 C  CD  . GLU A 1 233 ? 41.702 8.804   65.817 1.000 25.609  0 233 GLU A CD  1 ? 
ATOM   1820 O  OE1 . GLU A 1 233 ? 42.064 7.645   66.049 1.000 27.104  0 233 GLU A OE1 1 ? 
ATOM   1821 O  OE2 . GLU A 1 233 ? 42.460 9.761   65.750 1.000 24.501  0 233 GLU A OE2 1 ? 
ATOM   1822 N  N   . ASP A 1 234 ? 38.476 7.694   62.575 1.000 18.152  0 234 ASP A N   1 ? 
ATOM   1823 C  CA  . ASP A 1 234 ? 38.753 8.014   61.187 1.000 18.212  0 234 ASP A CA  1 ? 
ATOM   1824 C  C   . ASP A 1 234 ? 37.505 8.591   60.503 1.000 15.765  0 234 ASP A C   1 ? 
ATOM   1825 O  O   . ASP A 1 234 ? 37.588 9.533   59.703 1.000 16.166  0 234 ASP A O   1 ? 
ATOM   1826 C  CB  . ASP A 1 234 ? 39.213 6.749   60.476 1.000 18.695  0 234 ASP A CB  1 ? 
ATOM   1827 C  CG  . ASP A 1 234 ? 40.585 6.229   60.878 1.000 24.771  0 234 ASP A CG  1 ? 
ATOM   1828 O  OD1 . ASP A 1 234 ? 41.339 6.995   61.495 1.000 28.253  0 234 ASP A OD1 1 ? 
ATOM   1829 O  OD2 . ASP A 1 234 ? 40.844 5.031   60.625 1.000 27.359  0 234 ASP A OD2 1 ? 
ATOM   1830 N  N   . ALA A 1 235 ? 36.336 8.031   60.825 1.000 15.837  0 235 ALA A N   1 ? 
ATOM   1831 C  CA  . ALA A 1 235 ? 35.074 8.477   60.256 1.000 15.570  0 235 ALA A CA  1 ? 
ATOM   1832 C  C   . ALA A 1 235 ? 34.751 9.902   60.718 1.000 14.647  0 235 ALA A C   1 ? 
ATOM   1833 O  O   . ALA A 1 235 ? 34.420 10.754  59.918 1.000 14.716  0 235 ALA A O   1 ? 
ATOM   1834 C  CB  . ALA A 1 235 ? 33.961 7.527   60.627 1.000 15.324  0 235 ALA A CB  1 ? 
ATOM   1835 N  N   . LEU A 1 236 ? 34.874 10.165  62.014 1.000 14.175  0 236 LEU A N   1 ? 
ATOM   1836 C  CA  . LEU A 1 236 ? 34.644 11.503  62.526 1.000 15.227  0 236 LEU A CA  1 ? 
ATOM   1837 C  C   . LEU A 1 236 ? 35.598 12.519  61.901 1.000 13.477  0 236 LEU A C   1 ? 
ATOM   1838 O  O   . LEU A 1 236 ? 35.148 13.590  61.504 1.000 14.213  0 236 LEU A O   1 ? 
ATOM   1839 C  CB  . LEU A 1 236 ? 34.775 11.552  64.040 1.000 15.232  0 236 LEU A CB  1 ? 
ATOM   1840 C  CG  . LEU A 1 236 ? 33.823 10.685  64.865 1.000 17.730  0 236 LEU A CG  1 ? 
ATOM   1841 C  CD1 . LEU A 1 236 ? 34.157 10.933  66.347 1.000 18.495  0 236 LEU A CD1 1 ? 
ATOM   1842 C  CD2 . LEU A 1 236 ? 32.353 10.911  64.552 1.000 16.287  0 236 LEU A CD2 1 ? 
ATOM   1843 N  N   . LEU A 1 237 ? 36.899 12.194  61.780 1.000 13.832  0 237 LEU A N   1 ? 
ATOM   1844 C  CA  . LEU A 1 237 ? 37.829 13.121  61.126 1.000 14.381  0 237 LEU A CA  1 ? 
ATOM   1845 C  C   . LEU A 1 237 ? 37.443 13.380  59.673 1.000 13.469  0 237 LEU A C   1 ? 
ATOM   1846 O  O   . LEU A 1 237 ? 37.548 14.512  59.203 1.000 15.427  0 237 LEU A O   1 ? 
ATOM   1847 C  CB  . LEU A 1 237 ? 39.276 12.629  61.219 1.000 17.170  0 237 LEU A CB  1 ? 
ATOM   1848 C  CG  . LEU A 1 237 ? 39.884 12.595  62.616 1.000 18.397  0 237 LEU A CG  1 ? 
ATOM   1849 C  CD1 . LEU A 1 237 ? 41.191 11.867  62.551 1.000 17.395  0 237 LEU A CD1 1 ? 
ATOM   1850 C  CD2 . LEU A 1 237 ? 40.062 13.993  63.193 1.000 18.091  0 237 LEU A CD2 1 ? 
ATOM   1851 N  N   . ALA A 1 238 ? 37.005 12.340  58.931 1.000 13.939  0 238 ALA A N   1 ? 
ATOM   1852 C  CA  . ALA A 1 238 ? 36.666 12.527  57.538 1.000 14.252  0 238 ALA A CA  1 ? 
ATOM   1853 C  C   . ALA A 1 238 ? 35.456 13.455  57.407 1.000 13.618  0 238 ALA A C   1 ? 
ATOM   1854 O  O   . ALA A 1 238 ? 35.372 14.280  56.504 1.000 14.175  0 238 ALA A O   1 ? 
ATOM   1855 C  CB  . ALA A 1 238 ? 36.410 11.191  56.883 1.000 13.985  0 238 ALA A CB  1 ? 
ATOM   1856 N  N   . ILE A 1 239 ? 34.478 13.314  58.330 1.000 13.432  0 239 ILE A N   1 ? 
ATOM   1857 C  CA  . ILE A 1 239 ? 33.329 14.187  58.307 1.000 13.069  0 239 ILE A CA  1 ? 
ATOM   1858 C  C   . ILE A 1 239 ? 33.759 15.639  58.507 1.000 11.587  0 239 ILE A C   1 ? 
ATOM   1859 O  O   . ILE A 1 239 ? 33.372 16.525  57.740 1.000 12.750  0 239 ILE A O   1 ? 
ATOM   1860 C  CB  . ILE A 1 239 ? 32.285 13.780  59.359 1.000 14.377  0 239 ILE A CB  1 ? 
ATOM   1861 C  CG1 . ILE A 1 239 ? 31.720 12.420  59.019 1.000 13.639  0 239 ILE A CG1 1 ? 
ATOM   1862 C  CG2 . ILE A 1 239 ? 31.219 14.869  59.467 1.000 16.702  0 239 ILE A CG2 1 ? 
ATOM   1863 C  CD1 . ILE A 1 239 ? 30.885 11.833  60.135 1.000 14.869  0 239 ILE A CD1 1 ? 
ATOM   1864 N  N   . VAL A 1 240 ? 34.595 15.883  59.528 1.000 13.249  0 240 VAL A N   1 ? 
ATOM   1865 C  CA  . VAL A 1 240 ? 35.026 17.256  59.833 1.000 13.353  0 240 VAL A CA  1 ? 
ATOM   1866 C  C   . VAL A 1 240 ? 35.776 17.850  58.642 1.000 12.575  0 240 VAL A C   1 ? 
ATOM   1867 O  O   . VAL A 1 240 ? 35.481 18.962  58.231 1.000 12.992  0 240 VAL A O   1 ? 
ATOM   1868 C  CB  . VAL A 1 240 ? 35.909 17.253  61.091 1.000 13.717  0 240 VAL A CB  1 ? 
ATOM   1869 C  CG1 . VAL A 1 240 ? 36.607 18.611  61.267 1.000 13.457  0 240 VAL A CG1 1 ? 
ATOM   1870 C  CG2 . VAL A 1 240 ? 35.124 16.894  62.346 1.000 15.058  0 240 VAL A CG2 1 ? 
ATOM   1871 N  N   . LYS A 1 241 ? 36.748 17.072  58.104 1.000 13.283  0 241 LYS A N   1 ? 
ATOM   1872 C  CA  . LYS A 1 241 ? 37.577 17.520  56.988 1.000 13.327  0 241 LYS A CA  1 ? 
ATOM   1873 C  C   . LYS A 1 241 ? 36.745 17.806  55.750 1.000 13.789  0 241 LYS A C   1 ? 
ATOM   1874 O  O   . LYS A 1 241 ? 36.915 18.797  55.076 1.000 15.330  0 241 LYS A O   1 ? 
ATOM   1875 C  CB  . LYS A 1 241 ? 38.654 16.476  56.714 1.000 15.609  0 241 LYS A CB  1 ? 
ATOM   1876 C  CG  . LYS A 1 241 ? 39.709 16.449  57.799 1.000 16.086  0 241 LYS A CG  1 ? 
ATOM   1877 C  CD  . LYS A 1 241 ? 40.704 15.297  57.692 1.000 21.058  0 241 LYS A CD  1 ? 
ATOM   1878 C  CE  . LYS A 1 241 ? 41.846 15.436  58.661 1.000 23.054  0 241 LYS A CE  1 ? 
ATOM   1879 N  NZ  . LYS A 1 241 ? 42.697 14.260  58.528 1.000 29.194  0 241 LYS A NZ  1 ? 
ATOM   1880 N  N   . CYS A 1 242 ? 35.763 16.963  55.457 1.000 12.922  0 242 CYS A N   1 ? 
ATOM   1881 C  CA  . CYS A 1 242 ? 34.907 17.210  54.296 1.000 14.452  0 242 CYS A CA  1 ? 
ATOM   1882 C  C   . CYS A 1 242 ? 33.947 18.382  54.472 1.000 14.483  0 242 CYS A C   1 ? 
ATOM   1883 O  O   . CYS A 1 242 ? 33.599 19.060  53.502 1.000 16.081  0 242 CYS A O   1 ? 
ATOM   1884 C  CB  . CYS A 1 242 ? 34.128 15.949  53.940 1.000 14.302  0 242 CYS A CB  1 ? 
ATOM   1885 S  SG  . CYS A 1 242 ? 35.192 14.683  53.171 1.000 15.151  0 242 CYS A SG  1 ? 
ATOM   1886 N  N   . MET A 1 243 ? 33.560 18.666  55.721 1.000 14.870  0 243 MET A N   1 ? 
ATOM   1887 C  CA  . MET A 1 243 ? 32.734 19.827  56.004 1.000 14.845  0 243 MET A CA  1 ? 
ATOM   1888 C  C   . MET A 1 243 ? 33.555 21.103  55.835 1.000 16.381  0 243 MET A C   1 ? 
ATOM   1889 O  O   . MET A 1 243 ? 33.050 22.060  55.283 1.000 18.970  0 243 MET A O   1 ? 
ATOM   1890 C  CB  . MET A 1 243 ? 32.155 19.774  57.413 1.000 15.420  0 243 MET A CB  1 ? 
ATOM   1891 C  CG  . MET A 1 243 ? 31.094 18.768  57.583 1.000 16.605  0 243 MET A CG  1 ? 
ATOM   1892 S  SD  . MET A 1 243 ? 29.580 19.220  56.722 1.000 18.376  0 243 MET A SD  1 ? 
ATOM   1893 C  CE  . MET A 1 243 ? 28.548 17.754  56.935 1.000 20.618  0 243 MET A CE  1 ? 
ATOM   1894 N  N   . ARG A 1 244 ? 34.827 21.063  56.200 1.000 15.442  0 244 ARG A N   1 ? 
ATOM   1895 C  CA  . ARG A 1 244 ? 35.695 22.225  56.099 1.000 17.695  0 244 ARG A CA  1 ? 
ATOM   1896 C  C   . ARG A 1 244 ? 36.098 22.473  54.651 1.000 18.935  0 244 ARG A C   1 ? 
ATOM   1897 O  O   . ARG A 1 244 ? 35.952 23.596  54.171 1.000 18.477  0 244 ARG A O   1 ? 
ATOM   1898 C  CB  . ARG A 1 244 ? 36.958 22.091  56.957 1.000 18.575  0 244 ARG A CB  1 ? 
ATOM   1899 C  CG  . ARG A 1 244 ? 36.779 22.102  58.471 1.000 20.436  0 244 ARG A CG  1 ? 
ATOM   1900 C  CD  . ARG A 1 244 ? 38.149 22.160  59.173 1.000 20.637  0 244 ARG A CD  1 ? 
ATOM   1901 N  NE  . ARG A 1 244 ? 38.227 21.932  60.613 1.000 23.632  0 244 ARG A NE  1 ? 
ATOM   1902 C  CZ  . ARG A 1 244 ? 37.978 22.849  61.525 1.000 24.217  0 244 ARG A CZ  1 ? 
ATOM   1903 N  NH1 . ARG A 1 244 ? 37.443 23.992  61.166 1.000 31.528  0 244 ARG A NH1 1 ? 
ATOM   1904 N  NH2 . ARG A 1 244 ? 38.155 22.587  62.796 1.000 26.907  0 244 ARG A NH2 1 ? 
ATOM   1905 N  N   . ASN A 1 245 ? 36.653 21.441  53.989 1.000 16.076  0 245 ASN A N   1 ? 
ATOM   1906 C  CA  . ASN A 1 245 ? 37.100 21.606  52.622 1.000 16.738  0 245 ASN A CA  1 ? 
ATOM   1907 C  C   . ASN A 1 245 ? 37.356 20.239  52.010 1.000 14.765  0 245 ASN A C   1 ? 
ATOM   1908 O  O   . ASN A 1 245 ? 38.371 19.597  52.285 1.000 16.299  0 245 ASN A O   1 ? 
ATOM   1909 C  CB  . ASN A 1 245 ? 38.347 22.485  52.571 1.000 19.452  0 245 ASN A CB  1 ? 
ATOM   1910 C  CG  . ASN A 1 245 ? 38.665 22.889  51.159 1.000 22.004  0 245 ASN A CG  1 ? 
ATOM   1911 O  OD1 . ASN A 1 245 ? 38.842 22.045  50.282 1.000 22.099  0 245 ASN A OD1 1 ? 
ATOM   1912 N  ND2 . ASN A 1 245 ? 38.664 24.184  50.899 1.000 26.743  0 245 ASN A ND2 1 ? 
ATOM   1913 N  N   . LYS A 1 246 ? 36.454 19.785  51.159 1.000 16.187  0 246 LYS A N   1 ? 
ATOM   1914 C  CA  . LYS A 1 246 ? 36.586 18.435  50.620 1.000 16.791  0 246 LYS A CA  1 ? 
ATOM   1915 C  C   . LYS A 1 246 ? 37.818 18.280  49.708 1.000 16.005  0 246 LYS A C   1 ? 
ATOM   1916 O  O   . LYS A 1 246 ? 38.422 17.222  49.632 1.000 16.580  0 246 LYS A O   1 ? 
ATOM   1917 C  CB  . LYS A 1 246 ? 35.432 17.998  49.709 1.000 23.493  0 246 LYS A CB  1 ? 
ATOM   1918 C  CG  . LYS A 1 246 ? 34.175 17.687  50.399 1.000 26.241  0 246 LYS A CG  1 ? 
ATOM   1919 C  CD  . LYS A 1 246 ? 33.057 17.437  49.400 1.000 24.275  0 246 LYS A CD  1 ? 
ATOM   1920 C  CE  . LYS A 1 246 ? 31.838 17.745  50.151 1.000 26.026  0 246 LYS A CE  1 ? 
ATOM   1921 N  NZ  . LYS A 1 246 ? 30.643 17.185  49.548 1.000 25.182  0 246 LYS A NZ  1 ? 
ATOM   1922 N  N   . SER A 1 247 ? 38.193 19.332  48.989 1.000 17.650  0 247 SER A N   1 ? 
ATOM   1923 C  CA  . SER A 1 247 ? 39.367 19.247  48.127 1.000 17.304  0 247 SER A CA  1 ? 
ATOM   1924 C  C   . SER A 1 247 ? 40.622 18.972  48.950 1.000 16.280  0 247 SER A C   1 ? 
ATOM   1925 O  O   . SER A 1 247 ? 41.484 18.165  48.575 1.000 16.509  0 247 SER A O   1 ? 
ATOM   1926 C  CB  . SER A 1 247 ? 39.510 20.512  47.308 1.000 17.970  0 247 SER A CB  1 ? 
ATOM   1927 O  OG  . SER A 1 247 ? 38.380 20.672  46.472 1.000 22.043  0 247 SER A OG  1 ? 
ATOM   1928 N  N   . ALA A 1 248 ? 40.699 19.599  50.132 1.000 15.994  0 248 ALA A N   1 ? 
ATOM   1929 C  CA  . ALA A 1 248 ? 41.812 19.344  51.025 1.000 15.935  0 248 ALA A CA  1 ? 
ATOM   1930 C  C   . ALA A 1 248 ? 41.814 17.907  51.524 1.000 15.124  0 248 ALA A C   1 ? 
ATOM   1931 O  O   . ALA A 1 248 ? 42.867 17.286  51.652 1.000 14.213  0 248 ALA A O   1 ? 
ATOM   1932 C  CB  . ALA A 1 248 ? 41.830 20.298  52.181 1.000 17.751  0 248 ALA A CB  1 ? 
ATOM   1933 N  N   . TYR A 1 249 ? 40.605 17.407  51.870 1.000 15.204  0 249 TYR A N   1 ? 
ATOM   1934 C  CA  . TYR A 1 249 ? 40.478 16.031  52.305 1.000 12.759  0 249 TYR A CA  1 ? 
ATOM   1935 C  C   . TYR A 1 249 ? 41.005 15.063  51.264 1.000 12.809  0 249 TYR A C   1 ? 
ATOM   1936 O  O   . TYR A 1 249 ? 41.734 14.142  51.580 1.000 13.285  0 249 TYR A O   1 ? 
ATOM   1937 C  CB  . TYR A 1 249 ? 39.002 15.741  52.578 1.000 14.324  0 249 TYR A CB  1 ? 
ATOM   1938 C  CG  . TYR A 1 249 ? 38.712 14.277  52.840 1.000 14.370  0 249 TYR A CG  1 ? 
ATOM   1939 C  CD1 . TYR A 1 249 ? 39.055 13.696  54.061 1.000 14.070  0 249 TYR A CD1 1 ? 
ATOM   1940 C  CD2 . TYR A 1 249 ? 38.060 13.497  51.902 1.000 15.645  0 249 TYR A CD2 1 ? 
ATOM   1941 C  CE1 . TYR A 1 249 ? 38.793 12.365  54.318 1.000 14.643  0 249 TYR A CE1 1 ? 
ATOM   1942 C  CE2 . TYR A 1 249 ? 37.803 12.152  52.144 1.000 14.696  0 249 TYR A CE2 1 ? 
ATOM   1943 C  CZ  . TYR A 1 249 ? 38.116 11.611  53.376 1.000 15.277  0 249 TYR A CZ  1 ? 
ATOM   1944 O  OH  . TYR A 1 249 ? 37.887 10.287  53.609 1.000 16.838  0 249 TYR A OH  1 ? 
ATOM   1945 N  N   . PHE A 1 250 ? 40.634 15.277  50.014 1.000 12.460  0 250 PHE A N   1 ? 
ATOM   1946 C  CA  . PHE A 1 250 ? 41.101 14.427  48.944 1.000 12.703  0 250 PHE A CA  1 ? 
ATOM   1947 C  C   . PHE A 1 250 ? 42.599 14.590  48.667 1.000 12.041  0 250 PHE A C   1 ? 
ATOM   1948 O  O   . PHE A 1 250 ? 43.265 13.615  48.303 1.000 13.182  0 250 PHE A O   1 ? 
ATOM   1949 C  CB  . PHE A 1 250 ? 40.326 14.637  47.642 1.000 13.125  0 250 PHE A CB  1 ? 
ATOM   1950 C  CG  . PHE A 1 250 ? 38.936 14.024  47.718 1.000 13.922  0 250 PHE A CG  1 ? 
ATOM   1951 C  CD1 . PHE A 1 250 ? 38.781 12.659  47.894 1.000 15.201  0 250 PHE A CD1 1 ? 
ATOM   1952 C  CD2 . PHE A 1 250 ? 37.815 14.817  47.741 1.000 15.758  0 250 PHE A CD2 1 ? 
ATOM   1953 C  CE1 . PHE A 1 250 ? 37.500 12.097  47.946 1.000 16.374  0 250 PHE A CE1 1 ? 
ATOM   1954 C  CE2 . PHE A 1 250 ? 36.545 14.259  47.838 1.000 18.119  0 250 PHE A CE2 1 ? 
ATOM   1955 C  CZ  . PHE A 1 250 ? 36.402 12.916  48.004 1.000 16.337  0 250 PHE A CZ  1 ? 
ATOM   1956 N  N   . ALA A 1 251 ? 43.134 15.793  48.817 1.000 12.630  0 251 ALA A N   1 ? 
ATOM   1957 C  CA  . ALA A 1 251 ? 44.585 15.939  48.755 1.000 12.343  0 251 ALA A CA  1 ? 
ATOM   1958 C  C   . ALA A 1 251 ? 45.291 15.054  49.774 1.000 13.634  0 251 ALA A C   1 ? 
ATOM   1959 O  O   . ALA A 1 251 ? 46.301 14.404  49.469 1.000 13.882  0 251 ALA A O   1 ? 
ATOM   1960 C  CB  . ALA A 1 251 ? 44.979 17.376  48.941 1.000 12.372  0 251 ALA A CB  1 ? 
ATOM   1961 N  N   . GLU A 1 252 ? 44.781 15.057  51.022 1.000 14.235  0 252 GLU A N   1 ? 
ATOM   1962 C  CA  . GLU A 1 252 ? 45.330 14.202  52.065 1.000 15.339  0 252 GLU A CA  1 ? 
ATOM   1963 C  C   . GLU A 1 252 ? 45.225 12.708  51.708 1.000 14.298  0 252 GLU A C   1 ? 
ATOM   1964 O  O   . GLU A 1 252 ? 46.151 11.925  51.957 1.000 14.602  0 252 GLU A O   1 ? 
ATOM   1965 C  CB  . GLU A 1 252 ? 44.674 14.531  53.404 1.000 19.412  0 252 GLU A CB  1 ? 
ATOM   1966 C  CG  . GLU A 1 252 ? 45.163 13.625  54.527 1.000 29.864  0 252 GLU A CG  1 ? 
ATOM   1967 C  CD  . GLU A 1 252 ? 44.205 13.620  55.711 1.000 37.403  0 252 GLU A CD  1 ? 
ATOM   1968 O  OE1 . GLU A 1 252 ? 43.893 14.770  56.138 1.000 33.778  0 252 GLU A OE1 1 ? 
ATOM   1969 O  OE2 . GLU A 1 252 ? 43.723 12.497  56.126 1.000 41.651  0 252 GLU A OE2 1 ? 
ATOM   1970 N  N   . LYS A 1 253 ? 44.088 12.298  51.138 1.000 14.500  0 253 LYS A N   1 ? 
ATOM   1971 C  CA  . LYS A 1 253 ? 43.889 10.901  50.809 1.000 14.714  0 253 LYS A CA  1 ? 
ATOM   1972 C  C   . LYS A 1 253 ? 44.907 10.461  49.744 1.000 13.562  0 253 LYS A C   1 ? 
ATOM   1973 O  O   . LYS A 1 253 ? 45.424 9.341   49.783 1.000 14.587  0 253 LYS A O   1 ? 
ATOM   1974 C  CB  . LYS A 1 253 ? 42.487 10.601  50.265 1.000 16.793  0 253 LYS A CB  1 ? 
ATOM   1975 C  CG  . LYS A 1 253 ? 41.369 10.789  51.246 1.000 20.365  0 253 LYS A CG  1 ? 
ATOM   1976 C  CD  . LYS A 1 253 ? 41.266 9.609   52.199 1.000 26.166  0 253 LYS A CD  1 ? 
ATOM   1977 C  CE  . LYS A 1 253 ? 41.099 8.379   51.313 1.000 32.984  0 253 LYS A CE  1 ? 
ATOM   1978 N  NZ  . LYS A 1 253 ? 40.485 7.120   51.752 1.000 31.682  0 253 LYS A NZ  1 ? 
ATOM   1979 N  N   . LEU A 1 254 ? 45.158 11.320  48.744 1.000 14.284  0 254 LEU A N   1 ? 
ATOM   1980 C  CA  . LEU A 1 254 ? 46.152 11.020  47.709 1.000 12.664  0 254 LEU A CA  1 ? 
ATOM   1981 C  C   . LEU A 1 254 ? 47.547 10.934  48.311 1.000 13.679  0 254 LEU A C   1 ? 
ATOM   1982 O  O   . LEU A 1 254 ? 48.269 10.020  47.994 1.000 14.018  0 254 LEU A O   1 ? 
ATOM   1983 C  CB  . LEU A 1 254 ? 46.060 12.104  46.632 1.000 12.148  0 254 LEU A CB  1 ? 
ATOM   1984 C  CG  . LEU A 1 254 ? 44.792 12.032  45.762 1.000 12.402  0 254 LEU A CG  1 ? 
ATOM   1985 C  CD1 . LEU A 1 254 ? 44.568 13.317  45.042 1.000 13.152  0 254 LEU A CD1 1 ? 
ATOM   1986 C  CD2 . LEU A 1 254 ? 44.904 10.899  44.764 1.000 12.622  0 254 LEU A CD2 1 ? 
ATOM   1987 N  N   . TYR A 1 255 ? 47.896 11.916  49.151 1.000 13.809  0 255 TYR A N   1 ? 
ATOM   1988 C  CA  . TYR A 1 255 ? 49.160 11.867  49.867 1.000 14.386  0 255 TYR A CA  1 ? 
ATOM   1989 C  C   . TYR A 1 255 ? 49.336 10.522  50.561 1.000 14.241  0 255 TYR A C   1 ? 
ATOM   1990 O  O   . TYR A 1 255 ? 50.378 9.881   50.403 1.000 14.674  0 255 TYR A O   1 ? 
ATOM   1991 C  CB  . TYR A 1 255 ? 49.262 13.056  50.819 1.000 14.791  0 255 TYR A CB  1 ? 
ATOM   1992 C  CG  . TYR A 1 255 ? 50.548 13.086  51.634 1.000 16.181  0 255 TYR A CG  1 ? 
ATOM   1993 C  CD1 . TYR A 1 255 ? 51.729 13.617  51.129 1.000 16.040  0 255 TYR A CD1 1 ? 
ATOM   1994 C  CD2 . TYR A 1 255 ? 50.579 12.568  52.923 1.000 17.455  0 255 TYR A CD2 1 ? 
ATOM   1995 C  CE1 . TYR A 1 255 ? 52.888 13.670  51.898 1.000 17.236  0 255 TYR A CE1 1 ? 
ATOM   1996 C  CE2 . TYR A 1 255 ? 51.735 12.606  53.687 1.000 16.692  0 255 TYR A CE2 1 ? 
ATOM   1997 C  CZ  . TYR A 1 255 ? 52.903 13.108  53.155 1.000 17.988  0 255 TYR A CZ  1 ? 
ATOM   1998 O  OH  . TYR A 1 255 ? 54.047 13.193  53.942 1.000 19.543  0 255 TYR A OH  1 ? 
ATOM   1999 N  N   . LYS A 1 256 ? 48.356 10.149  51.386 1.000 13.634  0 256 LYS A N   1 ? 
ATOM   2000 C  CA  . LYS A 1 256 ? 48.431 8.938   52.185 1.000 14.701  0 256 LYS A CA  1 ? 
ATOM   2001 C  C   . LYS A 1 256 ? 48.546 7.709   51.295 1.000 14.586  0 256 LYS A C   1 ? 
ATOM   2002 O  O   . LYS A 1 256 ? 49.175 6.721   51.672 1.000 15.623  0 256 LYS A O   1 ? 
ATOM   2003 C  CB  . LYS A 1 256 ? 47.272 8.912   53.196 1.000 16.584  0 256 LYS A CB  1 ? 
ATOM   2004 C  CG  . LYS A 1 256 ? 47.457 9.904   54.339 1.000 21.525  0 256 LYS A CG  1 ? 
ATOM   2005 C  CD  . LYS A 1 256 ? 46.381 9.829   55.421 1.000 26.516  0 256 LYS A CD  1 ? 
ATOM   2006 C  CE  . LYS A 1 256 ? 46.447 10.921  56.473 1.000 32.561  0 256 LYS A CE  1 ? 
ATOM   2007 N  NZ  . LYS A 1 256 ? 47.604 10.809  57.351 1.000 41.206  0 256 LYS A NZ  1 ? 
ATOM   2008 N  N   . SER A 1 257 ? 47.912 7.736   50.116 1.000 14.691  0 257 SER A N   1 ? 
ATOM   2009 C  CA  . SER A 1 257 ? 47.880 6.581   49.262 1.000 13.933  0 257 SER A CA  1 ? 
ATOM   2010 C  C   . SER A 1 257 ? 49.264 6.305   48.666 1.000 13.259  0 257 SER A C   1 ? 
ATOM   2011 O  O   . SER A 1 257 ? 49.530 5.184   48.285 1.000 14.603  0 257 SER A O   1 ? 
ATOM   2012 C  CB  . SER A 1 257 ? 46.821 6.740   48.190 1.000 14.956  0 257 SER A CB  1 ? 
ATOM   2013 O  OG  . SER A 1 257 ? 47.252 7.592   47.137 1.000 14.052  0 257 SER A OG  1 ? 
ATOM   2014 N  N   . MET A 1 258 ? 50.126 7.314   48.586 1.000 11.966  0 258 MET A N   1 ? 
ATOM   2015 C  CA  . MET A 1 258 ? 51.376 7.186   47.846 1.000 12.417  0 258 MET A CA  1 ? 
ATOM   2016 C  C   . MET A 1 258 ? 52.611 7.334   48.727 1.000 12.163  0 258 MET A C   1 ? 
ATOM   2017 O  O   . MET A 1 258 ? 53.654 6.781   48.377 1.000 15.042  0 258 MET A O   1 ? 
ATOM   2018 C  CB  . MET A 1 258 ? 51.477 8.231   46.727 1.000 13.319  0 258 MET A CB  1 ? 
ATOM   2019 C  CG  . MET A 1 258 ? 50.617 7.928   45.532 1.000 12.897  0 258 MET A CG  1 ? 
ATOM   2020 S  SD  . MET A 1 258 ? 50.605 9.183   44.234 1.000 13.910  0 258 MET A SD  1 ? 
ATOM   2021 C  CE  . MET A 1 258 ? 49.513 10.433  44.910 1.000 14.292  0 258 MET A CE  1 ? 
ATOM   2022 N  N   . LYS A 1 259 ? 52.528 8.126   49.801 1.000 14.169  0 259 LYS A N   1 ? 
ATOM   2023 C  CA  . LYS A 1 259 ? 53.699 8.377   50.639 1.000 14.232  0 259 LYS A CA  1 ? 
ATOM   2024 C  C   . LYS A 1 259 ? 54.067 7.128   51.430 1.000 16.113  0 259 LYS A C   1 ? 
ATOM   2025 O  O   . LYS A 1 259 ? 53.208 6.561   52.072 1.000 15.956  0 259 LYS A O   1 ? 
ATOM   2026 C  CB  . LYS A 1 259 ? 53.380 9.525   51.608 1.000 15.932  0 259 LYS A CB  1 ? 
ATOM   2027 C  CG  . LYS A 1 259 ? 54.539 10.005  52.458 1.000 18.994  0 259 LYS A CG  1 ? 
ATOM   2028 C  CD  . LYS A 1 259 ? 55.659 10.686  51.693 1.000 21.389  0 259 LYS A CD  1 ? 
ATOM   2029 C  CE  . LYS A 1 259 ? 56.531 11.425  52.712 1.000 27.326  0 259 LYS A CE  1 ? 
ATOM   2030 N  NZ  . LYS A 1 259 ? 57.790 11.814  52.086 1.000 31.209  0 259 LYS A NZ  1 ? 
ATOM   2031 N  N   . GLY A 1 260 ? 55.363 6.809   51.439 1.000 16.014  0 260 GLY A N   1 ? 
ATOM   2032 C  CA  . GLY A 1 260 ? 55.863 5.758   52.328 1.000 16.857  0 260 GLY A CA  1 ? 
ATOM   2033 C  C   . GLY A 1 260 ? 55.924 4.395   51.678 1.000 18.922  0 260 GLY A C   1 ? 
ATOM   2034 O  O   . GLY A 1 260 ? 56.068 4.257   50.476 1.000 19.225  0 260 GLY A O   1 ? 
ATOM   2035 N  N   . LEU A 1 261 ? 55.919 3.366   52.530 1.000 18.122  0 261 LEU A N   1 ? 
ATOM   2036 C  CA  . LEU A 1 261 ? 56.110 2.006   52.087 1.000 20.470  0 261 LEU A CA  1 ? 
ATOM   2037 C  C   . LEU A 1 261 ? 54.804 1.501   51.486 1.000 23.529  0 261 LEU A C   1 ? 
ATOM   2038 O  O   . LEU A 1 261 ? 53.793 1.437   52.172 1.000 22.657  0 261 LEU A O   1 ? 
ATOM   2039 C  CB  . LEU A 1 261 ? 56.556 1.214   53.314 1.000 23.448  0 261 LEU A CB  1 ? 
ATOM   2040 C  CG  . LEU A 1 261 ? 56.929 -0.242  53.030 1.000 23.972  0 261 LEU A CG  1 ? 
ATOM   2041 C  CD1 . LEU A 1 261 ? 58.058 -0.356  52.032 1.000 22.652  0 261 LEU A CD1 1 ? 
ATOM   2042 C  CD2 . LEU A 1 261 ? 57.245 -0.916  54.349 1.000 24.572  0 261 LEU A CD2 1 ? 
ATOM   2043 N  N   . GLY A 1 262 ? 54.864 1.143   50.202 1.000 19.319  0 262 GLY A N   1 ? 
ATOM   2044 C  CA  . GLY A 1 262 ? 53.726 0.591   49.497 1.000 19.584  0 262 GLY A CA  1 ? 
ATOM   2045 C  C   . GLY A 1 262 ? 52.860 1.690   48.902 1.000 18.766  0 262 GLY A C   1 ? 
ATOM   2046 O  O   . GLY A 1 262 ? 53.057 2.856   49.238 1.000 22.058  0 262 GLY A O   1 ? 
ATOM   2047 N  N   . THR A 1 263 ? 51.951 1.301   47.990 1.000 16.646  0 263 THR A N   1 ? 
ATOM   2048 C  CA  . THR A 1 263 ? 50.995 2.231   47.403 1.000 17.367  0 263 THR A CA  1 ? 
ATOM   2049 C  C   . THR A 1 263 ? 49.609 1.624   47.497 1.000 17.238  0 263 THR A C   1 ? 
ATOM   2050 O  O   . THR A 1 263 ? 49.419 0.464   47.124 1.000 18.004  0 263 THR A O   1 ? 
ATOM   2051 C  CB  . THR A 1 263 ? 51.348 2.517   45.957 1.000 19.418  0 263 THR A CB  1 ? 
ATOM   2052 O  OG1 . THR A 1 263 ? 52.619 3.186   45.981 1.000 22.946  0 263 THR A OG1 1 ? 
ATOM   2053 C  CG2 . THR A 1 263 ? 50.326 3.411   45.260 1.000 18.513  0 263 THR A CG2 1 ? 
ATOM   2054 N  N   . ASP A 1 264 ? 48.672 2.450   47.936 1.000 14.354  0 264 ASP A N   1 ? 
ATOM   2055 C  CA  . ASP A 1 264 ? 47.264 2.096   47.942 1.000 13.330  0 264 ASP A CA  1 ? 
ATOM   2056 C  C   . ASP A 1 264 ? 46.642 2.465   46.596 1.000 13.639  0 264 ASP A C   1 ? 
ATOM   2057 O  O   . ASP A 1 264 ? 46.017 3.514   46.450 1.000 13.839  0 264 ASP A O   1 ? 
ATOM   2058 C  CB  . ASP A 1 264 ? 46.575 2.719   49.122 1.000 14.756  0 264 ASP A CB  1 ? 
ATOM   2059 C  CG  . ASP A 1 264 ? 45.096 2.395   49.233 1.000 15.094  0 264 ASP A CG  1 ? 
ATOM   2060 O  OD1 . ASP A 1 264 ? 44.575 1.625   48.385 1.000 16.255  0 264 ASP A OD1 1 ? 
ATOM   2061 O  OD2 . ASP A 1 264 ? 44.484 2.950   50.146 1.000 18.874  0 264 ASP A OD2 1 ? 
ATOM   2062 N  N   . ASP A 1 265 ? 46.817 1.574   45.616 1.000 14.687  0 265 ASP A N   1 ? 
ATOM   2063 C  CA  . ASP A 1 265 ? 46.367 1.840   44.258 1.000 13.862  0 265 ASP A CA  1 ? 
ATOM   2064 C  C   . ASP A 1 265 ? 44.849 1.972   44.210 1.000 13.590  0 265 ASP A C   1 ? 
ATOM   2065 O  O   . ASP A 1 265 ? 44.347 2.831   43.488 1.000 13.595  0 265 ASP A O   1 ? 
ATOM   2066 C  CB  . ASP A 1 265 ? 46.838 0.790   43.267 1.000 15.659  0 265 ASP A CB  1 ? 
ATOM   2067 C  CG  . ASP A 1 265 ? 48.351 0.737   43.085 1.000 18.431  0 265 ASP A CG  1 ? 
ATOM   2068 O  OD1 . ASP A 1 265 ? 48.913 1.718   42.595 1.000 19.312  0 265 ASP A OD1 1 ? 
ATOM   2069 O  OD2 . ASP A 1 265 ? 48.943 -0.257  43.547 1.000 24.425  0 265 ASP A OD2 1 ? 
ATOM   2070 N  N   . ASN A 1 266 ? 44.109 1.176   44.982 1.000 13.372  0 266 ASN A N   1 ? 
ATOM   2071 C  CA  . ASN A 1 266 ? 42.660 1.283   44.945 1.000 13.908  0 266 ASN A CA  1 ? 
ATOM   2072 C  C   . ASN A 1 266 ? 42.189 2.691   45.304 1.000 14.026  0 266 ASN A C   1 ? 
ATOM   2073 O  O   . ASN A 1 266 ? 41.287 3.236   44.649 1.000 16.110  0 266 ASN A O   1 ? 
ATOM   2074 C  CB  . ASN A 1 266 ? 41.950 0.262   45.824 1.000 15.784  0 266 ASN A CB  1 ? 
ATOM   2075 C  CG  . ASN A 1 266 ? 41.983 -1.142  45.289 1.000 18.791  0 266 ASN A CG  1 ? 
ATOM   2076 O  OD1 . ASN A 1 266 ? 42.006 -2.112  46.064 1.000 25.472  0 266 ASN A OD1 1 ? 
ATOM   2077 N  ND2 . ASN A 1 266 ? 41.929 -1.309  43.990 1.000 16.278  0 266 ASN A ND2 1 ? 
ATOM   2078 N  N   . THR A 1 267 ? 42.749 3.316   46.344 1.000 13.578  0 267 THR A N   1 ? 
ATOM   2079 C  CA  . THR A 1 267 ? 42.372 4.664   46.741 1.000 13.365  0 267 THR A CA  1 ? 
ATOM   2080 C  C   . THR A 1 267 ? 42.857 5.704   45.727 1.000 12.870  0 267 THR A C   1 ? 
ATOM   2081 O  O   . THR A 1 267 ? 42.099 6.575   45.323 1.000 12.514  0 267 THR A O   1 ? 
ATOM   2082 C  CB  . THR A 1 267 ? 42.922 4.959   48.134 1.000 14.454  0 267 THR A CB  1 ? 
ATOM   2083 O  OG1 . THR A 1 267 ? 42.338 4.056   49.068 1.000 15.333  0 267 THR A OG1 1 ? 
ATOM   2084 C  CG2 . THR A 1 267 ? 42.648 6.386   48.564 1.000 14.555  0 267 THR A CG2 1 ? 
ATOM   2085 N  N   . LEU A 1 268 ? 44.120 5.593   45.289 1.000 12.442  0 268 LEU A N   1 ? 
ATOM   2086 C  CA  . LEU A 1 268 ? 44.671 6.480   44.276 1.000 12.027  0 268 LEU A CA  1 ? 
ATOM   2087 C  C   . LEU A 1 268 ? 43.755 6.536   43.055 1.000 11.426  0 268 LEU A C   1 ? 
ATOM   2088 O  O   . LEU A 1 268 ? 43.415 7.621   42.597 1.000 11.667  0 268 LEU A O   1 ? 
ATOM   2089 C  CB  . LEU A 1 268 ? 46.110 6.054   43.963 1.000 11.646  0 268 LEU A CB  1 ? 
ATOM   2090 C  CG  . LEU A 1 268 ? 46.823 6.800   42.840 1.000 12.350  0 268 LEU A CG  1 ? 
ATOM   2091 C  CD1 . LEU A 1 268 ? 46.895 8.280   43.144 1.000 12.617  0 268 LEU A CD1 1 ? 
ATOM   2092 C  CD2 . LEU A 1 268 ? 48.213 6.227   42.571 1.000 13.432  0 268 LEU A CD2 1 ? 
ATOM   2093 N  N   . ILE A 1 269 ? 43.422 5.359   42.523 1.000 13.345  0 269 ILE A N   1 ? 
ATOM   2094 C  CA  . ILE A 1 269 ? 42.611 5.261   41.339 1.000 12.212  0 269 ILE A CA  1 ? 
ATOM   2095 C  C   . ILE A 1 269 ? 41.238 5.863   41.587 1.000 13.288  0 269 ILE A C   1 ? 
ATOM   2096 O  O   . ILE A 1 269 ? 40.764 6.678   40.811 1.000 12.693  0 269 ILE A O   1 ? 
ATOM   2097 C  CB  . ILE A 1 269 ? 42.507 3.797   40.892 1.000 12.944  0 269 ILE A CB  1 ? 
ATOM   2098 C  CG1 . ILE A 1 269 ? 43.859 3.317   40.331 1.000 12.905  0 269 ILE A CG1 1 ? 
ATOM   2099 C  CG2 . ILE A 1 269 ? 41.381 3.658   39.883 1.000 14.063  0 269 ILE A CG2 1 ? 
ATOM   2100 C  CD1 . ILE A 1 269 ? 43.990 1.831   40.033 1.000 12.396  0 269 ILE A CD1 1 ? 
ATOM   2101 N  N   . ARG A 1 270 ? 40.600 5.483   42.687 1.000 11.526  0 270 ARG A N   1 ? 
ATOM   2102 C  CA  . ARG A 1 270 ? 39.233 5.946   42.919 1.000 12.709  0 270 ARG A CA  1 ? 
ATOM   2103 C  C   . ARG A 1 270 ? 39.155 7.460   43.054 1.000 12.912  0 270 ARG A C   1 ? 
ATOM   2104 O  O   . ARG A 1 270 ? 38.257 8.095   42.524 1.000 13.711  0 270 ARG A O   1 ? 
ATOM   2105 C  CB  . ARG A 1 270 ? 38.645 5.329   44.193 1.000 15.270  0 270 ARG A CB  1 ? 
ATOM   2106 C  CG  . ARG A 1 270 ? 37.237 5.832   44.478 1.000 15.560  0 270 ARG A CG  1 ? 
ATOM   2107 C  CD  . ARG A 1 270 ? 36.654 5.079   45.668 1.000 15.409  0 270 ARG A CD  1 ? 
ATOM   2108 N  NE  . ARG A 1 270 ? 37.515 5.177   46.844 1.000 15.985  0 270 ARG A NE  1 ? 
ATOM   2109 C  CZ  . ARG A 1 270 ? 38.330 4.234   47.346 1.000 16.540  0 270 ARG A CZ  1 ? 
ATOM   2110 N  NH1 . ARG A 1 270 ? 38.366 3.005   46.865 1.000 18.394  0 270 ARG A NH1 1 ? 
ATOM   2111 N  NH2 . ARG A 1 270 ? 39.146 4.545   48.330 1.000 16.998  0 270 ARG A NH2 1 ? 
ATOM   2112 N  N   . VAL A 1 271 ? 40.114 8.062   43.762 1.000 12.682  0 271 VAL A N   1 ? 
ATOM   2113 C  CA  . VAL A 1 271 ? 40.107 9.501   43.962 1.000 12.493  0 271 VAL A CA  1 ? 
ATOM   2114 C  C   . VAL A 1 271 ? 40.366 10.187  42.626 1.000 12.541  0 271 VAL A C   1 ? 
ATOM   2115 O  O   . VAL A 1 271 ? 39.655 11.135  42.279 1.000 12.763  0 271 VAL A O   1 ? 
ATOM   2116 C  CB  . VAL A 1 271 ? 41.128 9.950   45.021 1.000 13.708  0 271 VAL A CB  1 ? 
ATOM   2117 C  CG1 . VAL A 1 271 ? 41.307 11.456  45.032 1.000 14.397  0 271 VAL A CG1 1 ? 
ATOM   2118 C  CG2 . VAL A 1 271 ? 40.690 9.447   46.375 1.000 14.243  0 271 VAL A CG2 1 ? 
ATOM   2119 N  N   . MET A 1 272 ? 41.359 9.714   41.869 1.000 11.984  0 272 MET A N   1 ? 
ATOM   2120 C  CA  . MET A 1 272 ? 41.687 10.365  40.599 1.000 12.154  0 272 MET A CA  1 ? 
ATOM   2121 C  C   . MET A 1 272 ? 40.526 10.266  39.603 1.000 12.507  0 272 MET A C   1 ? 
ATOM   2122 O  O   . MET A 1 272 ? 40.182 11.268  38.969 1.000 15.558  0 272 MET A O   1 ? 
ATOM   2123 C  CB  . MET A 1 272 ? 42.980 9.802   40.006 1.000 12.522  0 272 MET A CB  1 ? 
ATOM   2124 C  CG  . MET A 1 272 ? 44.233 10.159  40.787 1.000 12.780  0 272 MET A CG  1 ? 
ATOM   2125 S  SD  . MET A 1 272 ? 44.492 11.901  41.179 1.000 13.607  0 272 MET A SD  1 ? 
ATOM   2126 C  CE  . MET A 1 272 ? 44.690 12.574  39.523 1.000 14.331  0 272 MET A CE  1 ? 
ATOM   2127 N  N   . VAL A 1 273 ? 39.901 9.103   39.497 1.000 12.466  0 273 VAL A N   1 ? 
ATOM   2128 C  CA  . VAL A 1 273 ? 38.768 8.944   38.585 1.000 14.062  0 273 VAL A CA  1 ? 
ATOM   2129 C  C   . VAL A 1 273 ? 37.555 9.736   39.060 1.000 15.712  0 273 VAL A C   1 ? 
ATOM   2130 O  O   . VAL A 1 273 ? 36.927 10.430  38.239 1.000 17.371  0 273 VAL A O   1 ? 
ATOM   2131 C  CB  . VAL A 1 273 ? 38.471 7.449   38.447 1.000 13.394  0 273 VAL A CB  1 ? 
ATOM   2132 C  CG1 . VAL A 1 273 ? 37.133 7.153   37.732 1.000 13.861  0 273 VAL A CG1 1 ? 
ATOM   2133 C  CG2 . VAL A 1 273 ? 39.617 6.739   37.763 1.000 14.630  0 273 VAL A CG2 1 ? 
ATOM   2134 N  N   . SER A 1 274 ? 37.224 9.648   40.358 1.000 12.912  0 274 SER A N   1 ? 
ATOM   2135 C  CA  . SER A 1 274 ? 35.983 10.249  40.875 1.000 14.243  0 274 SER A CA  1 ? 
ATOM   2136 C  C   . SER A 1 274 ? 36.050 11.766  41.023 1.000 15.413  0 274 SER A C   1 ? 
ATOM   2137 O  O   . SER A 1 274 ? 34.988 12.421  41.079 1.000 17.019  0 274 SER A O   1 ? 
ATOM   2138 C  CB  . SER A 1 274 ? 35.554 9.616   42.154 1.000 14.707  0 274 SER A CB  1 ? 
ATOM   2139 O  OG  . SER A 1 274 ? 36.455 9.953   43.184 1.000 15.799  0 274 SER A OG  1 ? 
ATOM   2140 N  N   . ARG A 1 275 ? 37.248 12.366  41.061 1.000 13.573  0 275 ARG A N   1 ? 
ATOM   2141 C  CA  . ARG A 1 275 ? 37.353 13.803  41.312 1.000 13.878  0 275 ARG A CA  1 ? 
ATOM   2142 C  C   . ARG A 1 275 ? 37.900 14.594  40.120 1.000 13.872  0 275 ARG A C   1 ? 
ATOM   2143 O  O   . ARG A 1 275 ? 37.868 15.823  40.166 1.000 14.503  0 275 ARG A O   1 ? 
ATOM   2144 C  CB  . ARG A 1 275 ? 38.152 14.133  42.594 1.000 14.648  0 275 ARG A CB  1 ? 
ATOM   2145 C  CG  . ARG A 1 275 ? 37.677 13.440  43.863 1.000 15.426  0 275 ARG A CG  1 ? 
ATOM   2146 C  CD  . ARG A 1 275 ? 36.214 13.663  44.118 1.000 17.716  0 275 ARG A CD  1 ? 
ATOM   2147 N  NE  . ARG A 1 275 ? 35.981 15.048  44.549 1.000 18.452  0 275 ARG A NE  1 ? 
ATOM   2148 C  CZ  . ARG A 1 275 ? 34.818 15.478  45.080 1.000 22.509  0 275 ARG A CZ  1 ? 
ATOM   2149 N  NH1 . ARG A 1 275 ? 33.770 14.676  45.125 1.000 24.089  0 275 ARG A NH1 1 ? 
ATOM   2150 N  NH2 . ARG A 1 275 ? 34.703 16.696  45.584 1.000 21.672  0 275 ARG A NH2 1 ? 
ATOM   2151 N  N   . ALA A 1 276 ? 38.427 13.930  39.080 1.000 15.633  0 276 ALA A N   1 ? 
ATOM   2152 C  CA  . ALA A 1 276 ? 39.010 14.621  37.922 1.000 15.154  0 276 ALA A CA  1 ? 
ATOM   2153 C  C   . ALA A 1 276 ? 38.105 15.700  37.327 1.000 17.840  0 276 ALA A C   1 ? 
ATOM   2154 O  O   . ALA A 1 276 ? 38.590 16.756  36.897 1.000 16.650  0 276 ALA A O   1 ? 
ATOM   2155 C  CB  . ALA A 1 276 ? 39.387 13.603  36.867 1.000 16.088  0 276 ALA A CB  1 ? 
ATOM   2156 N  N   . GLU A 1 277 ? 36.792 15.436  37.283 1.000 17.717  0 277 GLU A N   1 ? 
ATOM   2157 C  CA  . GLU A 1 277 ? 35.868 16.360  36.649 1.000 19.891  0 277 GLU A CA  1 ? 
ATOM   2158 C  C   . GLU A 1 277 ? 35.274 17.351  37.621 1.000 20.425  0 277 GLU A C   1 ? 
ATOM   2159 O  O   . GLU A 1 277 ? 34.536 18.227  37.204 1.000 23.940  0 277 GLU A O   1 ? 
ATOM   2160 C  CB  . GLU A 1 277 ? 34.652 15.628  36.088 1.000 23.848  0 277 GLU A CB  1 ? 
ATOM   2161 C  CG  . GLU A 1 277 ? 34.996 14.694  34.955 1.000 24.445  0 277 GLU A CG  1 ? 
ATOM   2162 C  CD  . GLU A 1 277 ? 33.712 14.175  34.307 1.000 25.260  0 277 GLU A CD  1 ? 
ATOM   2163 O  OE1 . GLU A 1 277 ? 32.537 14.674  34.328 1.000 27.343  0 277 GLU A OE1 1 ? 
ATOM   2164 O  OE2 . GLU A 1 277 ? 34.008 13.109  33.813 1.000 23.320  0 277 GLU A OE2 1 ? 
ATOM   2165 N  N   . ILE A 1 278 ? 35.520 17.187  38.920 1.000 18.378  0 278 ILE A N   1 ? 
ATOM   2166 C  CA  . ILE A 1 278 ? 34.845 17.973  39.930 1.000 20.659  0 278 ILE A CA  1 ? 
ATOM   2167 C  C   . ILE A 1 278 ? 35.778 19.059  40.456 1.000 18.448  0 278 ILE A C   1 ? 
ATOM   2168 O  O   . ILE A 1 278 ? 35.502 20.254  40.381 1.000 19.251  0 278 ILE A O   1 ? 
ATOM   2169 C  CB  . ILE A 1 278 ? 34.319 17.062  41.052 1.000 21.738  0 278 ILE A CB  1 ? 
ATOM   2170 C  CG1 . ILE A 1 278 ? 33.323 16.048  40.483 1.000 25.546  0 278 ILE A CG1 1 ? 
ATOM   2171 C  CG2 . ILE A 1 278 ? 33.729 17.872  42.201 1.000 24.387  0 278 ILE A CG2 1 ? 
ATOM   2172 C  CD1 . ILE A 1 278 ? 32.858 15.006  41.476 1.000 27.041  0 278 ILE A CD1 1 ? 
ATOM   2173 N  N   . ASP A 1 279 ? 36.900 18.663  41.066 1.000 17.711  0 279 ASP A N   1 ? 
ATOM   2174 C  CA  . ASP A 1 279 ? 37.661 19.606  41.875 1.000 16.706  0 279 ASP A CA  1 ? 
ATOM   2175 C  C   . ASP A 1 279 ? 39.157 19.306  41.876 1.000 14.528  0 279 ASP A C   1 ? 
ATOM   2176 O  O   . ASP A 1 279 ? 39.861 19.750  42.775 1.000 15.047  0 279 ASP A O   1 ? 
ATOM   2177 C  CB  . ASP A 1 279 ? 37.153 19.690  43.307 1.000 17.900  0 279 ASP A CB  1 ? 
ATOM   2178 C  CG  . ASP A 1 279 ? 37.151 18.408  44.124 1.000 21.618  0 279 ASP A CG  1 ? 
ATOM   2179 O  OD1 . ASP A 1 279 ? 37.351 17.309  43.538 1.000 20.309  0 279 ASP A OD1 1 ? 
ATOM   2180 O  OD2 . ASP A 1 279 ? 36.933 18.509  45.347 1.000 22.935  0 279 ASP A OD2 1 ? 
ATOM   2181 N  N   . MET A 1 280 ? 39.645 18.623  40.853 1.000 14.053  0 280 MET A N   1 ? 
ATOM   2182 C  CA  . MET A 1 280 ? 41.053 18.262  40.790 1.000 13.649  0 280 MET A CA  1 ? 
ATOM   2183 C  C   . MET A 1 280 ? 41.940 19.503  40.819 1.000 14.119  0 280 MET A C   1 ? 
ATOM   2184 O  O   . MET A 1 280 ? 43.036 19.409  41.363 1.000 14.673  0 280 MET A O   1 ? 
ATOM   2185 C  CB  . MET A 1 280 ? 41.359 17.407  39.554 1.000 16.434  0 280 MET A CB  1 ? 
ATOM   2186 C  CG  . MET A 1 280 ? 42.741 16.747  39.574 1.000 15.342  0 280 MET A CG  1 ? 
ATOM   2187 S  SD  . MET A 1 280 ? 43.114 15.693  40.986 1.000 16.108  0 280 MET A SD  1 ? 
ATOM   2188 C  CE  . MET A 1 280 ? 41.823 14.443  40.825 1.000 17.815  0 280 MET A CE  1 ? 
ATOM   2189 N  N   . LEU A 1 281 ? 41.553 20.652  40.227 1.000 14.689  0 281 LEU A N   1 ? 
ATOM   2190 C  CA  . LEU A 1 281 ? 42.464 21.783  40.277 1.000 16.662  0 281 LEU A CA  1 ? 
ATOM   2191 C  C   . LEU A 1 281 ? 42.599 22.305  41.709 1.000 15.825  0 281 LEU A C   1 ? 
ATOM   2192 O  O   . LEU A 1 281 ? 43.675 22.702  42.157 1.000 15.605  0 281 LEU A O   1 ? 
ATOM   2193 C  CB  . LEU A 1 281 ? 41.956 22.873  39.339 1.000 18.104  0 281 LEU A CB  1 ? 
ATOM   2194 C  CG  . LEU A 1 281 ? 42.112 22.600  37.840 1.000 19.933  0 281 LEU A CG  1 ? 
ATOM   2195 C  CD1 . LEU A 1 281 ? 41.427 23.713  37.034 1.000 22.626  0 281 LEU A CD1 1 ? 
ATOM   2196 C  CD2 . LEU A 1 281 ? 43.568 22.524  37.426 1.000 23.180  0 281 LEU A CD2 1 ? 
ATOM   2197 N  N   . ASP A 1 282 ? 41.502 22.256  42.460 1.000 16.879  0 282 ASP A N   1 ? 
ATOM   2198 C  CA  . ASP A 1 282 ? 41.535 22.627  43.869 1.000 17.262  0 282 ASP A CA  1 ? 
ATOM   2199 C  C   . ASP A 1 282 ? 42.328 21.618  44.681 1.000 15.939  0 282 ASP A C   1 ? 
ATOM   2200 O  O   . ASP A 1 282 ? 43.047 21.994  45.599 1.000 16.551  0 282 ASP A O   1 ? 
ATOM   2201 C  CB  . ASP A 1 282 ? 40.125 22.734  44.410 1.000 18.508  0 282 ASP A CB  1 ? 
ATOM   2202 C  CG  . ASP A 1 282 ? 39.258 23.698  43.623 1.000 23.582  0 282 ASP A CG  1 ? 
ATOM   2203 O  OD1 . ASP A 1 282 ? 39.510 24.917  43.770 1.000 30.613  0 282 ASP A OD1 1 ? 
ATOM   2204 O  OD2 . ASP A 1 282 ? 38.436 23.208  42.813 1.000 24.834  0 282 ASP A OD2 1 ? 
ATOM   2205 N  N   . ILE A 1 283 ? 42.137 20.335  44.414 1.000 14.513  0 283 ILE A N   1 ? 
ATOM   2206 C  CA  . ILE A 1 283 ? 42.899 19.295  45.091 1.000 14.287  0 283 ILE A CA  1 ? 
ATOM   2207 C  C   . ILE A 1 283 ? 44.398 19.546  44.896 1.000 15.401  0 283 ILE A C   1 ? 
ATOM   2208 O  O   . ILE A 1 283 ? 45.159 19.505  45.869 1.000 14.948  0 283 ILE A O   1 ? 
ATOM   2209 C  CB  . ILE A 1 283 ? 42.491 17.906  44.586 1.000 13.216  0 283 ILE A CB  1 ? 
ATOM   2210 C  CG1 . ILE A 1 283 ? 41.054 17.578  45.031 1.000 13.179  0 283 ILE A CG1 1 ? 
ATOM   2211 C  CG2 . ILE A 1 283 ? 43.473 16.862  45.071 1.000 14.469  0 283 ILE A CG2 1 ? 
ATOM   2212 C  CD1 . ILE A 1 283 ? 40.537 16.274  44.450 1.000 13.773  0 283 ILE A CD1 1 ? 
ATOM   2213 N  N   . ARG A 1 284 ? 44.812 19.796  43.653 1.000 15.277  0 284 ARG A N   1 ? 
ATOM   2214 C  CA  . ARG A 1 284 ? 46.205 20.124  43.345 1.000 14.994  0 284 ARG A CA  1 ? 
ATOM   2215 C  C   . ARG A 1 284 ? 46.736 21.298  44.170 1.000 15.452  0 284 ARG A C   1 ? 
ATOM   2216 O  O   . ARG A 1 284 ? 47.825 21.210  44.743 1.000 14.970  0 284 ARG A O   1 ? 
ATOM   2217 C  CB  . ARG A 1 284 ? 46.354 20.509  41.878 1.000 16.517  0 284 ARG A CB  1 ? 
ATOM   2218 C  CG  . ARG A 1 284 ? 46.443 19.230  41.096 1.000 16.945  0 284 ARG A CG  1 ? 
ATOM   2219 C  CD  . ARG A 1 284 ? 46.258 19.503  39.627 1.000 20.027  0 284 ARG A CD  1 ? 
ATOM   2220 N  NE  . ARG A 1 284 ? 47.175 20.517  39.099 1.000 21.596  0 284 ARG A NE  1 ? 
ATOM   2221 C  CZ  . ARG A 1 284 ? 47.163 21.001  37.849 1.000 25.718  0 284 ARG A CZ  1 ? 
ATOM   2222 N  NH1 . ARG A 1 284 ? 46.497 20.388  36.890 1.000 20.468  0 284 ARG A NH1 1 ? 
ATOM   2223 N  NH2 . ARG A 1 284 ? 47.875 22.076  37.562 1.000 27.288  0 284 ARG A NH2 1 ? 
ATOM   2224 N  N   . ALA A 1 285 ? 45.940 22.364  44.243 1.000 16.524  0 285 ALA A N   1 ? 
ATOM   2225 C  CA  . ALA A 1 285 ? 46.335 23.551  44.978 1.000 18.021  0 285 ALA A CA  1 ? 
ATOM   2226 C  C   . ALA A 1 285 ? 46.529 23.234  46.456 1.000 17.750  0 285 ALA A C   1 ? 
ATOM   2227 O  O   . ALA A 1 285 ? 47.522 23.643  47.049 1.000 16.386  0 285 ALA A O   1 ? 
ATOM   2228 C  CB  . ALA A 1 285 ? 45.327 24.658  44.775 1.000 18.834  0 285 ALA A CB  1 ? 
ATOM   2229 N  N   . HIS A 1 286 ? 45.545 22.556  47.079 1.000 15.559  0 286 HIS A N   1 ? 
ATOM   2230 C  CA  . HIS A 1 286 ? 45.684 22.171  48.475 1.000 15.338  0 286 HIS A CA  1 ? 
ATOM   2231 C  C   . HIS A 1 286 ? 46.864 21.230  48.716 1.000 16.189  0 286 HIS A C   1 ? 
ATOM   2232 O  O   . HIS A 1 286 ? 47.529 21.351  49.740 1.000 17.135  0 286 HIS A O   1 ? 
ATOM   2233 C  CB  . HIS A 1 286 ? 44.376 21.584  49.008 1.000 17.035  0 286 HIS A CB  1 ? 
ATOM   2234 C  CG  . HIS A 1 286 ? 43.311 22.568  49.225 1.000 17.506  0 286 HIS A CG  1 ? 
ATOM   2235 N  ND1 . HIS A 1 286 ? 43.288 23.327  50.370 1.000 21.515  0 286 HIS A ND1 1 ? 
ATOM   2236 C  CD2 . HIS A 1 286 ? 42.304 23.002  48.479 1.000 22.262  0 286 HIS A CD2 1 ? 
ATOM   2237 C  CE1 . HIS A 1 286 ? 42.259 24.161  50.321 1.000 22.479  0 286 HIS A CE1 1 ? 
ATOM   2238 N  NE2 . HIS A 1 286 ? 41.667 24.007  49.176 1.000 22.490  0 286 HIS A NE2 1 ? 
ATOM   2239 N  N   . PHE A 1 287 ? 47.083 20.265  47.815 1.000 14.956  0 287 PHE A N   1 ? 
ATOM   2240 C  CA  . PHE A 1 287 ? 48.169 19.300  47.946 1.000 14.131  0 287 PHE A CA  1 ? 
ATOM   2241 C  C   . PHE A 1 287 ? 49.502 20.053  48.027 1.000 14.509  0 287 PHE A C   1 ? 
ATOM   2242 O  O   . PHE A 1 287 ? 50.314 19.811  48.907 1.000 14.697  0 287 PHE A O   1 ? 
ATOM   2243 C  CB  . PHE A 1 287 ? 48.107 18.336  46.750 1.000 14.292  0 287 PHE A CB  1 ? 
ATOM   2244 C  CG  . PHE A 1 287 ? 49.065 17.174  46.885 1.000 13.477  0 287 PHE A CG  1 ? 
ATOM   2245 C  CD1 . PHE A 1 287 ? 50.416 17.324  46.616 1.000 12.892  0 287 PHE A CD1 1 ? 
ATOM   2246 C  CD2 . PHE A 1 287 ? 48.637 15.923  47.313 1.000 12.293  0 287 PHE A CD2 1 ? 
ATOM   2247 C  CE1 . PHE A 1 287 ? 51.283 16.248  46.747 1.000 12.540  0 287 PHE A CE1 1 ? 
ATOM   2248 C  CE2 . PHE A 1 287 ? 49.507 14.864  47.492 1.000 12.450  0 287 PHE A CE2 1 ? 
ATOM   2249 C  CZ  . PHE A 1 287 ? 50.837 15.023  47.197 1.000 12.968  0 287 PHE A CZ  1 ? 
ATOM   2250 N  N   . LYS A 1 288 ? 49.690 21.010  47.130 1.000 15.511  0 288 LYS A N   1 ? 
ATOM   2251 C  CA  . LYS A 1 288 ? 50.921 21.780  47.089 1.000 17.942  0 288 LYS A CA  1 ? 
ATOM   2252 C  C   . LYS A 1 288 ? 51.083 22.583  48.383 1.000 17.163  0 288 LYS A C   1 ? 
ATOM   2253 O  O   . LYS A 1 288 ? 52.178 22.610  48.946 1.000 17.560  0 288 LYS A O   1 ? 
ATOM   2254 C  CB  . LYS A 1 288 ? 50.977 22.684  45.858 1.000 19.808  0 288 LYS A CB  1 ? 
ATOM   2255 C  CG  . LYS A 1 288 ? 52.308 23.440  45.808 1.000 24.237  0 288 LYS A CG  1 ? 
ATOM   2256 C  CD  . LYS A 1 288 ? 53.529 22.565  45.625 1.000 27.454  0 288 LYS A CD  1 ? 
ATOM   2257 C  CE  . LYS A 1 288 ? 54.862 23.269  45.610 1.000 33.124  0 288 LYS A CE  1 ? 
ATOM   2258 N  NZ  . LYS A 1 288 ? 54.947 24.150  44.435 1.000 31.465  0 288 LYS A NZ  1 ? 
ATOM   2259 N  N   . ARG A 1 289 ? 50.007 23.189  48.894 1.000 18.392  0 289 ARG A N   1 ? 
ATOM   2260 C  CA  . ARG A 1 289 ? 50.081 23.967  50.136 1.000 21.416  0 289 ARG A CA  1 ? 
ATOM   2261 C  C   . ARG A 1 289 ? 50.417 23.069  51.322 1.000 20.152  0 289 ARG A C   1 ? 
ATOM   2262 O  O   . ARG A 1 289 ? 51.205 23.415  52.200 1.000 19.302  0 289 ARG A O   1 ? 
ATOM   2263 C  CB  . ARG A 1 289 ? 48.738 24.674  50.394 1.000 24.640  0 289 ARG A CB  1 ? 
ATOM   2264 C  CG  . ARG A 1 289 ? 48.368 25.836  49.482 1.000 33.377  0 289 ARG A CG  1 ? 
ATOM   2265 C  CD  . ARG A 1 289 ? 49.377 26.993  49.647 1.000 46.083  0 289 ARG A CD  1 ? 
ATOM   2266 N  NE  . ARG A 1 289 ? 48.972 28.241  48.985 1.000 57.926  0 289 ARG A NE  1 ? 
ATOM   2267 C  CZ  . ARG A 1 289 ? 49.774 29.290  48.797 1.000 62.100  0 289 ARG A CZ  1 ? 
ATOM   2268 N  NH1 . ARG A 1 289 ? 51.017 29.253  49.241 1.000 64.167  0 289 ARG A NH1 1 ? 
ATOM   2269 N  NH2 . ARG A 1 289 ? 49.339 30.367  48.165 1.000 62.362  0 289 ARG A NH2 1 ? 
ATOM   2270 N  N   . LEU A 1 290 ? 49.805 21.896  51.384 1.000 18.022  0 290 LEU A N   1 ? 
ATOM   2271 C  CA  . LEU A 1 290 ? 49.982 20.991  52.502 1.000 18.372  0 290 LEU A CA  1 ? 
ATOM   2272 C  C   . LEU A 1 290 ? 51.368 20.351  52.503 1.000 17.454  0 290 LEU A C   1 ? 
ATOM   2273 O  O   . LEU A 1 290 ? 51.967 20.176  53.571 1.000 18.727  0 290 LEU A O   1 ? 
ATOM   2274 C  CB  . LEU A 1 290 ? 48.907 19.908  52.504 1.000 19.449  0 290 LEU A CB  1 ? 
ATOM   2275 C  CG  . LEU A 1 290 ? 47.485 20.356  52.871 1.000 20.545  0 290 LEU A CG  1 ? 
ATOM   2276 C  CD1 . LEU A 1 290 ? 46.514 19.263  52.477 1.000 23.565  0 290 LEU A CD1 1 ? 
ATOM   2277 C  CD2 . LEU A 1 290 ? 47.398 20.645  54.363 1.000 22.572  0 290 LEU A CD2 1 ? 
ATOM   2278 N  N   . TYR A 1 291 ? 51.858 19.914  51.332 1.000 16.581  0 291 TYR A N   1 ? 
ATOM   2279 C  CA  . TYR A 1 291 ? 52.975 18.996  51.268 1.000 15.819  0 291 TYR A CA  1 ? 
ATOM   2280 C  C   . TYR A 1 291 ? 54.208 19.556  50.562 1.000 18.574  0 291 TYR A C   1 ? 
ATOM   2281 O  O   . TYR A 1 291 ? 55.243 18.892  50.594 1.000 19.431  0 291 TYR A O   1 ? 
ATOM   2282 C  CB  . TYR A 1 291 ? 52.525 17.729  50.543 1.000 17.596  0 291 TYR A CB  1 ? 
ATOM   2283 C  CG  . TYR A 1 291 ? 51.372 17.056  51.279 1.000 16.298  0 291 TYR A CG  1 ? 
ATOM   2284 C  CD1 . TYR A 1 291 ? 51.472 16.705  52.626 1.000 17.132  0 291 TYR A CD1 1 ? 
ATOM   2285 C  CD2 . TYR A 1 291 ? 50.130 16.901  50.674 1.000 16.362  0 291 TYR A CD2 1 ? 
ATOM   2286 C  CE1 . TYR A 1 291 ? 50.416 16.136  53.314 1.000 17.662  0 291 TYR A CE1 1 ? 
ATOM   2287 C  CE2 . TYR A 1 291 ? 49.052 16.360  51.362 1.000 15.484  0 291 TYR A CE2 1 ? 
ATOM   2288 C  CZ  . TYR A 1 291 ? 49.196 15.944  52.679 1.000 16.134  0 291 TYR A CZ  1 ? 
ATOM   2289 O  OH  . TYR A 1 291 ? 48.143 15.405  53.388 1.000 18.852  0 291 TYR A OH  1 ? 
ATOM   2290 N  N   . GLY A 1 292 ? 54.095 20.750  49.976 1.000 17.134  0 292 GLY A N   1 ? 
ATOM   2291 C  CA  . GLY A 1 292 ? 55.225 21.447  49.357 1.000 17.806  0 292 GLY A CA  1 ? 
ATOM   2292 C  C   . GLY A 1 292 ? 55.798 20.744  48.126 1.000 18.686  0 292 GLY A C   1 ? 
ATOM   2293 O  O   . GLY A 1 292 ? 56.971 20.959  47.775 1.000 19.193  0 292 GLY A O   1 ? 
ATOM   2294 N  N   . LYS A 1 293 ? 55.017 19.840  47.520 1.000 17.014  0 293 LYS A N   1 ? 
ATOM   2295 C  CA  . LYS A 1 293 ? 55.387 19.110  46.323 1.000 15.966  0 293 LYS A CA  1 ? 
ATOM   2296 C  C   . LYS A 1 293 ? 54.134 19.119  45.450 1.000 14.996  0 293 LYS A C   1 ? 
ATOM   2297 O  O   . LYS A 1 293 ? 53.040 19.272  45.960 1.000 15.269  0 293 LYS A O   1 ? 
ATOM   2298 C  CB  . LYS A 1 293 ? 55.747 17.646  46.630 1.000 16.331  0 293 LYS A CB  1 ? 
ATOM   2299 C  CG  . LYS A 1 293 ? 56.884 17.371  47.621 1.000 17.769  0 293 LYS A CG  1 ? 
ATOM   2300 C  CD  . LYS A 1 293 ? 58.238 17.874  47.137 1.000 19.118  0 293 LYS A CD  1 ? 
ATOM   2301 C  CE  . LYS A 1 293 ? 59.489 17.540  47.951 1.000 22.191  0 293 LYS A CE  1 ? 
ATOM   2302 N  NZ  . LYS A 1 293 ? 59.785 16.124  47.827 1.000 25.487  0 293 LYS A NZ  1 ? 
ATOM   2303 N  N   . SER A 1 294 ? 54.286 19.006  44.131 1.000 13.630  0 294 SER A N   1 ? 
ATOM   2304 C  CA  . SER A 1 294 ? 53.106 18.907  43.273 1.000 13.706  0 294 SER A CA  1 ? 
ATOM   2305 C  C   . SER A 1 294 ? 52.493 17.510  43.310 1.000 13.055  0 294 SER A C   1 ? 
ATOM   2306 O  O   . SER A 1 294 ? 53.184 16.493  43.481 1.000 13.108  0 294 SER A O   1 ? 
ATOM   2307 C  CB  . SER A 1 294 ? 53.439 19.272  41.841 1.000 14.022  0 294 SER A CB  1 ? 
ATOM   2308 O  OG  . SER A 1 294 ? 54.246 18.281  41.241 1.000 15.164  0 294 SER A OG  1 ? 
ATOM   2309 N  N   . LEU A 1 295 ? 51.157 17.458  43.145 1.000 12.383  0 295 LEU A N   1 ? 
ATOM   2310 C  CA  . LEU A 1 295 ? 50.491 16.160  43.038 1.000 14.103  0 295 LEU A CA  1 ? 
ATOM   2311 C  C   . LEU A 1 295 ? 51.047 15.399  41.835 1.000 12.253  0 295 LEU A C   1 ? 
ATOM   2312 O  O   . LEU A 1 295 ? 51.261 14.195  41.891 1.000 12.651  0 295 LEU A O   1 ? 
ATOM   2313 C  CB  . LEU A 1 295 ? 48.983 16.346  42.916 1.000 13.658  0 295 LEU A CB  1 ? 
ATOM   2314 C  CG  . LEU A 1 295 ? 48.179 15.083  42.613 1.000 12.973  0 295 LEU A CG  1 ? 
ATOM   2315 C  CD1 . LEU A 1 295 ? 48.402 14.024  43.698 1.000 13.158  0 295 LEU A CD1 1 ? 
ATOM   2316 C  CD2 . LEU A 1 295 ? 46.681 15.461  42.485 1.000 13.171  0 295 LEU A CD2 1 ? 
ATOM   2317 N  N   . TYR A 1 296 ? 51.193 16.091  40.697 1.000 12.901  0 296 TYR A N   1 ? 
ATOM   2318 C  CA  . TYR A 1 296 ? 51.757 15.496  39.499 1.000 15.027  0 296 TYR A CA  1 ? 
ATOM   2319 C  C   . TYR A 1 296 ? 53.027 14.722  39.840 1.000 13.069  0 296 TYR A C   1 ? 
ATOM   2320 O  O   . TYR A 1 296 ? 53.231 13.588  39.414 1.000 12.817  0 296 TYR A O   1 ? 
ATOM   2321 C  CB  . TYR A 1 296 ? 52.053 16.626  38.499 1.000 17.202  0 296 TYR A CB  1 ? 
ATOM   2322 C  CG  . TYR A 1 296 ? 52.622 16.161  37.173 1.000 18.579  0 296 TYR A CG  1 ? 
ATOM   2323 C  CD1 . TYR A 1 296 ? 53.981 15.917  37.032 1.000 22.417  0 296 TYR A CD1 1 ? 
ATOM   2324 C  CD2 . TYR A 1 296 ? 51.795 16.043  36.062 1.000 21.495  0 296 TYR A CD2 1 ? 
ATOM   2325 C  CE1 . TYR A 1 296 ? 54.513 15.528  35.810 1.000 23.820  0 296 TYR A CE1 1 ? 
ATOM   2326 C  CE2 . TYR A 1 296 ? 52.311 15.651  34.841 1.000 23.412  0 296 TYR A CE2 1 ? 
ATOM   2327 C  CZ  . TYR A 1 296 ? 53.667 15.395  34.726 1.000 26.729  0 296 TYR A CZ  1 ? 
ATOM   2328 O  OH  . TYR A 1 296 ? 54.156 14.990  33.517 1.000 34.299  0 296 TYR A OH  1 ? 
ATOM   2329 N  N   . SER A 1 297 ? 53.930 15.358  40.578 1.000 13.820  0 297 SER A N   1 ? 
ATOM   2330 C  CA  . SER A 1 297 ? 55.227 14.764  40.850 1.000 14.311  0 297 SER A CA  1 ? 
ATOM   2331 C  C   . SER A 1 297 ? 55.149 13.519  41.739 1.000 12.925  0 297 SER A C   1 ? 
ATOM   2332 O  O   . SER A 1 297 ? 55.958 12.590  41.652 1.000 12.985  0 297 SER A O   1 ? 
ATOM   2333 C  CB  . SER A 1 297 ? 56.175 15.790  41.509 1.000 13.804  0 297 SER A CB  1 ? 
ATOM   2334 O  OG  . SER A 1 297 ? 55.825 16.046  42.861 1.000 13.722  0 297 SER A OG  1 ? 
ATOM   2335 N  N   . PHE A 1 298 ? 54.150 13.476  42.644 1.000 12.683  0 298 PHE A N   1 ? 
ATOM   2336 C  CA  . PHE A 1 298 ? 53.875 12.290  43.440 1.000 13.793  0 298 PHE A CA  1 ? 
ATOM   2337 C  C   . PHE A 1 298 ? 53.502 11.132  42.525 1.000 13.742  0 298 PHE A C   1 ? 
ATOM   2338 O  O   . PHE A 1 298 ? 54.053 10.048  42.602 1.000 13.936  0 298 PHE A O   1 ? 
ATOM   2339 C  CB  . PHE A 1 298 ? 52.779 12.519  44.493 1.000 15.093  0 298 PHE A CB  1 ? 
ATOM   2340 C  CG  . PHE A 1 298 ? 53.306 12.782  45.888 1.000 14.688  0 298 PHE A CG  1 ? 
ATOM   2341 C  CD1 . PHE A 1 298 ? 54.114 13.882  46.146 1.000 16.028  0 298 PHE A CD1 1 ? 
ATOM   2342 C  CD2 . PHE A 1 298 ? 52.973 11.940  46.937 1.000 15.101  0 298 PHE A CD2 1 ? 
ATOM   2343 C  CE1 . PHE A 1 298 ? 54.591 14.111  47.434 1.000 15.754  0 298 PHE A CE1 1 ? 
ATOM   2344 C  CE2 . PHE A 1 298 ? 53.440 12.204  48.214 1.000 15.585  0 298 PHE A CE2 1 ? 
ATOM   2345 C  CZ  . PHE A 1 298 ? 54.255 13.288  48.444 1.000 15.300  0 298 PHE A CZ  1 ? 
ATOM   2346 N  N   . ILE A 1 299 ? 52.525 11.379  41.656 1.000 14.026  0 299 ILE A N   1 ? 
ATOM   2347 C  CA  . ILE A 1 299 ? 52.080 10.333  40.745 1.000 13.601  0 299 ILE A CA  1 ? 
ATOM   2348 C  C   . ILE A 1 299 ? 53.260 9.887   39.858 1.000 14.335  0 299 ILE A C   1 ? 
ATOM   2349 O  O   . ILE A 1 299 ? 53.477 8.703   39.606 1.000 14.252  0 299 ILE A O   1 ? 
ATOM   2350 C  CB  . ILE A 1 299 ? 50.908 10.840  39.905 1.000 13.615  0 299 ILE A CB  1 ? 
ATOM   2351 C  CG1 . ILE A 1 299 ? 49.688 11.083  40.746 1.000 13.281  0 299 ILE A CG1 1 ? 
ATOM   2352 C  CG2 . ILE A 1 299 ? 50.629 9.895   38.734 1.000 13.768  0 299 ILE A CG2 1 ? 
ATOM   2353 C  CD1 . ILE A 1 299 ? 48.576 11.803  40.002 1.000 14.423  0 299 ILE A CD1 1 ? 
ATOM   2354 N  N   . LYS A 1 300 ? 53.987 10.851  39.311 1.000 14.861  0 300 LYS A N   1 ? 
ATOM   2355 C  CA  . LYS A 1 300 ? 55.116 10.561  38.435 1.000 16.228  0 300 LYS A CA  1 ? 
ATOM   2356 C  C   . LYS A 1 300 ? 56.123 9.663   39.156 1.000 16.643  0 300 LYS A C   1 ? 
ATOM   2357 O  O   . LYS A 1 300 ? 56.661 8.723   38.576 1.000 17.170  0 300 LYS A O   1 ? 
ATOM   2358 C  CB  . LYS A 1 300 ? 55.775 11.840  37.908 1.000 17.724  0 300 LYS A CB  1 ? 
ATOM   2359 C  CG  . LYS A 1 300 ? 56.970 11.630  36.949 1.000 23.950  0 300 LYS A CG  1 ? 
ATOM   2360 C  CD  . LYS A 1 300 ? 57.998 12.767  37.043 1.000 30.619  0 300 LYS A CD  1 ? 
ATOM   2361 C  CE  . LYS A 1 300 ? 59.263 12.671  36.216 1.000 30.881  0 300 LYS A CE  1 ? 
ATOM   2362 N  NZ  . LYS A 1 300 ? 60.356 11.828  36.698 1.000 31.486  0 300 LYS A NZ  1 ? 
ATOM   2363 N  N   . GLY A 1 301 ? 56.368 9.942   40.447 1.000 15.426  0 301 GLY A N   1 ? 
ATOM   2364 C  CA  . GLY A 1 301 ? 57.435 9.267   41.173 1.000 17.636  0 301 GLY A CA  1 ? 
ATOM   2365 C  C   . GLY A 1 301 ? 57.013 7.929   41.771 1.000 17.628  0 301 GLY A C   1 ? 
ATOM   2366 O  O   . GLY A 1 301 ? 57.858 7.117   42.145 1.000 19.555  0 301 GLY A O   1 ? 
ATOM   2367 N  N   . ASP A 1 302 ? 55.702 7.676   41.838 1.000 15.274  0 302 ASP A N   1 ? 
ATOM   2368 C  CA  . ASP A 1 302 ? 55.205 6.501   42.511 1.000 16.678  0 302 ASP A CA  1 ? 
ATOM   2369 C  C   . ASP A 1 302 ? 54.537 5.477   41.596 1.000 16.630  0 302 ASP A C   1 ? 
ATOM   2370 O  O   . ASP A 1 302 ? 54.251 4.376   42.052 1.000 22.134  0 302 ASP A O   1 ? 
ATOM   2371 C  CB  . ASP A 1 302 ? 54.255 6.912   43.619 1.000 17.229  0 302 ASP A CB  1 ? 
ATOM   2372 C  CG  . ASP A 1 302 ? 54.039 5.835   44.672 1.000 19.338  0 302 ASP A CG  1 ? 
ATOM   2373 O  OD1 . ASP A 1 302 ? 55.022 5.310   45.201 1.000 20.571  0 302 ASP A OD1 1 ? 
ATOM   2374 O  OD2 . ASP A 1 302 ? 52.889 5.440   44.840 1.000 20.851  0 302 ASP A OD2 1 ? 
ATOM   2375 N  N   . THR A 1 303 ? 54.280 5.811   40.323 1.000 15.781  0 303 THR A N   1 ? 
ATOM   2376 C  CA  . THR A 1 303 ? 53.666 4.887   39.390 1.000 14.903  0 303 THR A CA  1 ? 
ATOM   2377 C  C   . THR A 1 303 ? 54.521 4.800   38.126 1.000 16.501  0 303 THR A C   1 ? 
ATOM   2378 O  O   . THR A 1 303 ? 55.385 5.635   37.889 1.000 16.380  0 303 THR A O   1 ? 
ATOM   2379 C  CB  . THR A 1 303 ? 52.217 5.314   39.106 1.000 15.571  0 303 THR A CB  1 ? 
ATOM   2380 O  OG1 . THR A 1 303 ? 52.184 6.556   38.412 1.000 16.432  0 303 THR A OG1 1 ? 
ATOM   2381 C  CG2 . THR A 1 303 ? 51.406 5.442   40.378 1.000 16.154  0 303 THR A CG2 1 ? 
ATOM   2382 N  N   . SER A 1 304 ? 54.177 3.853   37.246 1.000 16.132  0 304 SER A N   1 ? 
ATOM   2383 C  CA  . SER A 1 304 ? 54.878 3.762   35.980 1.000 18.282  0 304 SER A CA  1 ? 
ATOM   2384 C  C   . SER A 1 304 ? 53.963 3.257   34.871 1.000 16.069  0 304 SER A C   1 ? 
ATOM   2385 O  O   . SER A 1 304 ? 52.802 2.917   35.086 1.000 16.782  0 304 SER A O   1 ? 
ATOM   2386 C  CB  . SER A 1 304 ? 56.141 2.927   36.122 1.000 23.320  0 304 SER A CB  1 ? 
ATOM   2387 O  OG  . SER A 1 304 ? 55.825 1.579   36.408 1.000 30.605  0 304 SER A OG  1 ? 
ATOM   2388 N  N   . GLY A 1 305 ? 54.521 3.205   33.674 1.000 16.714  0 305 GLY A N   1 ? 
ATOM   2389 C  CA  . GLY A 1 305 ? 53.803 2.615   32.566 1.000 16.631  0 305 GLY A CA  1 ? 
ATOM   2390 C  C   . GLY A 1 305 ? 52.582 3.436   32.119 1.000 15.116  0 305 GLY A C   1 ? 
ATOM   2391 O  O   . GLY A 1 305 ? 52.506 4.666   32.278 1.000 15.221  0 305 GLY A O   1 ? 
ATOM   2392 N  N   . ASP A 1 306 ? 51.661 2.744   31.446 1.000 16.866  0 306 ASP A N   1 ? 
ATOM   2393 C  CA  . ASP A 1 306 ? 50.445 3.370   30.944 1.000 16.992  0 306 ASP A CA  1 ? 
ATOM   2394 C  C   . ASP A 1 306 ? 49.535 3.835   32.095 1.000 13.177  0 306 ASP A C   1 ? 
ATOM   2395 O  O   . ASP A 1 306 ? 48.817 4.819   31.968 1.000 13.180  0 306 ASP A O   1 ? 
ATOM   2396 C  CB  . ASP A 1 306 ? 49.751 2.463   29.939 1.000 18.859  0 306 ASP A CB  1 ? 
ATOM   2397 C  CG  . ASP A 1 306 ? 50.550 2.274   28.656 1.000 22.619  0 306 ASP A CG  1 ? 
ATOM   2398 O  OD1 . ASP A 1 306 ? 51.083 3.271   28.185 1.000 29.192  0 306 ASP A OD1 1 ? 
ATOM   2399 O  OD2 . ASP A 1 306 ? 50.632 1.132   28.172 1.000 24.250  0 306 ASP A OD2 1 ? 
ATOM   2400 N  N   . TYR A 1 307 ? 49.574 3.098   33.204 1.000 14.484  0 307 TYR A N   1 ? 
ATOM   2401 C  CA  . TYR A 1 307 ? 48.931 3.506   34.440 1.000 12.612  0 307 TYR A CA  1 ? 
ATOM   2402 C  C   . TYR A 1 307 ? 49.332 4.929   34.853 1.000 12.958  0 307 TYR A C   1 ? 
ATOM   2403 O  O   . TYR A 1 307 ? 48.503 5.815   35.028 1.000 12.696  0 307 TYR A O   1 ? 
ATOM   2404 C  CB  . TYR A 1 307 ? 49.317 2.507   35.508 1.000 13.442  0 307 TYR A CB  1 ? 
ATOM   2405 C  CG  . TYR A 1 307 ? 48.805 2.765   36.909 1.000 12.887  0 307 TYR A CG  1 ? 
ATOM   2406 C  CD1 . TYR A 1 307 ? 47.491 3.153   37.174 1.000 13.575  0 307 TYR A CD1 1 ? 
ATOM   2407 C  CD2 . TYR A 1 307 ? 49.608 2.470   37.983 1.000 14.271  0 307 TYR A CD2 1 ? 
ATOM   2408 C  CE1 . TYR A 1 307 ? 47.028 3.287   38.471 1.000 13.669  0 307 TYR A CE1 1 ? 
ATOM   2409 C  CE2 . TYR A 1 307 ? 49.165 2.622   39.281 1.000 13.687  0 307 TYR A CE2 1 ? 
ATOM   2410 C  CZ  . TYR A 1 307 ? 47.864 3.012   39.531 1.000 14.844  0 307 TYR A CZ  1 ? 
ATOM   2411 O  OH  . TYR A 1 307 ? 47.427 3.165   40.824 1.000 15.406  0 307 TYR A OH  1 ? 
ATOM   2412 N  N   . ARG A 1 308 ? 50.632 5.171   34.942 1.000 13.297  0 308 ARG A N   1 ? 
ATOM   2413 C  CA  . ARG A 1 308 ? 51.152 6.503   35.236 1.000 12.663  0 308 ARG A CA  1 ? 
ATOM   2414 C  C   . ARG A 1 308 ? 50.655 7.503   34.182 1.000 12.437  0 308 ARG A C   1 ? 
ATOM   2415 O  O   . ARG A 1 308 ? 50.227 8.614   34.525 1.000 14.323  0 308 ARG A O   1 ? 
ATOM   2416 C  CB  . ARG A 1 308 ? 52.692 6.515   35.287 1.000 13.980  0 308 ARG A CB  1 ? 
ATOM   2417 C  CG  . ARG A 1 308 ? 53.275 7.919   35.304 1.000 13.462  0 308 ARG A CG  1 ? 
ATOM   2418 C  CD  . ARG A 1 308 ? 54.748 8.016   35.717 1.000 13.750  0 308 ARG A CD  1 ? 
ATOM   2419 N  NE  . ARG A 1 308 ? 55.594 7.275   34.771 1.000 16.012  0 308 ARG A NE  1 ? 
ATOM   2420 C  CZ  . ARG A 1 308 ? 56.932 7.217   34.895 1.000 16.587  0 308 ARG A CZ  1 ? 
ATOM   2421 N  NH1 . ARG A 1 308 ? 57.507 7.702   35.958 1.000 17.392  0 308 ARG A NH1 1 ? 
ATOM   2422 N  NH2 . ARG A 1 308 ? 57.665 6.586   33.985 1.000 18.620  0 308 ARG A NH2 1 ? 
ATOM   2423 N  N   . LYS A 1 309 ? 50.729 7.148   32.884 1.000 12.364  0 309 LYS A N   1 ? 
ATOM   2424 C  CA  . LYS A 1 309 ? 50.390 8.105   31.852 1.000 12.439  0 309 LYS A CA  1 ? 
ATOM   2425 C  C   . LYS A 1 309 ? 48.961 8.583   32.032 1.000 13.338  0 309 LYS A C   1 ? 
ATOM   2426 O  O   . LYS A 1 309 ? 48.716 9.777   31.912 1.000 13.500  0 309 LYS A O   1 ? 
ATOM   2427 C  CB  . LYS A 1 309 ? 50.530 7.507   30.454 1.000 14.995  0 309 LYS A CB  1 ? 
ATOM   2428 C  CG  . LYS A 1 309 ? 51.982 7.246   30.031 1.000 19.406  0 309 LYS A CG  1 ? 
ATOM   2429 C  CD  . LYS A 1 309 ? 52.149 6.600   28.646 1.000 25.077  0 309 LYS A CD  1 ? 
ATOM   2430 C  CE  . LYS A 1 309 ? 53.604 6.656   28.217 1.000 28.826  0 309 LYS A CE  1 ? 
ATOM   2431 N  NZ  . LYS A 1 309 ? 53.810 6.108   26.871 1.000 32.732  0 309 LYS A NZ  1 ? 
ATOM   2432 N  N   . VAL A 1 310 ? 48.025 7.660   32.291 1.000 13.150  0 310 VAL A N   1 ? 
ATOM   2433 C  CA  . VAL A 1 310 ? 46.640 8.105   32.354 1.000 12.727  0 310 VAL A CA  1 ? 
ATOM   2434 C  C   . VAL A 1 310 ? 46.407 8.884   33.649 1.000 12.654  0 310 VAL A C   1 ? 
ATOM   2435 O  O   . VAL A 1 310 ? 45.692 9.890   33.662 1.000 12.365  0 310 VAL A O   1 ? 
ATOM   2436 C  CB  . VAL A 1 310 ? 45.645 6.963   32.160 1.000 13.759  0 310 VAL A CB  1 ? 
ATOM   2437 C  CG1 . VAL A 1 310 ? 45.741 5.913   33.234 1.000 13.729  0 310 VAL A CG1 1 ? 
ATOM   2438 C  CG2 . VAL A 1 310 ? 44.217 7.487   31.997 1.000 13.799  0 310 VAL A CG2 1 ? 
ATOM   2439 N  N   . LEU A 1 311 ? 47.013 8.459   34.752 1.000 12.189  0 311 LEU A N   1 ? 
ATOM   2440 C  CA  . LEU A 1 311 ? 46.831 9.229   35.984 1.000 13.422  0 311 LEU A CA  1 ? 
ATOM   2441 C  C   . LEU A 1 311 ? 47.340 10.656  35.822 1.000 13.622  0 311 LEU A C   1 ? 
ATOM   2442 O  O   . LEU A 1 311 ? 46.766 11.594  36.389 1.000 12.357  0 311 LEU A O   1 ? 
ATOM   2443 C  CB  . LEU A 1 311 ? 47.516 8.559   37.156 1.000 12.681  0 311 LEU A CB  1 ? 
ATOM   2444 C  CG  . LEU A 1 311 ? 46.977 7.220   37.646 1.000 13.739  0 311 LEU A CG  1 ? 
ATOM   2445 C  CD1 . LEU A 1 311 ? 47.804 6.703   38.796 1.000 15.203  0 311 LEU A CD1 1 ? 
ATOM   2446 C  CD2 . LEU A 1 311 ? 45.522 7.336   38.025 1.000 15.217  0 311 LEU A CD2 1 ? 
ATOM   2447 N  N   . LEU A 1 312 ? 48.465 10.829  35.112 1.000 12.852  0 312 LEU A N   1 ? 
ATOM   2448 C  CA  . LEU A 1 312 ? 49.001 12.179  34.893 1.000 13.505  0 312 LEU A CA  1 ? 
ATOM   2449 C  C   . LEU A 1 312 ? 48.085 13.060  34.050 1.000 14.175  0 312 LEU A C   1 ? 
ATOM   2450 O  O   . LEU A 1 312 ? 47.952 14.254  34.330 1.000 14.888  0 312 LEU A O   1 ? 
ATOM   2451 C  CB  . LEU A 1 312 ? 50.415 12.175  34.320 1.000 14.332  0 312 LEU A CB  1 ? 
ATOM   2452 C  CG  . LEU A 1 312 ? 51.487 11.559  35.219 1.000 14.321  0 312 LEU A CG  1 ? 
ATOM   2453 C  CD1 . LEU A 1 312 ? 52.766 11.405  34.383 1.000 17.186  0 312 LEU A CD1 1 ? 
ATOM   2454 C  CD2 . LEU A 1 312 ? 51.690 12.368  36.502 1.000 14.540  0 312 LEU A CD2 1 ? 
ATOM   2455 N  N   . VAL A 1 313 ? 47.369 12.499  33.073 1.000 13.034  0 313 VAL A N   1 ? 
ATOM   2456 C  CA  . VAL A 1 313 ? 46.356 13.276  32.377 1.000 13.430  0 313 VAL A CA  1 ? 
ATOM   2457 C  C   . VAL A 1 313 ? 45.196 13.667  33.302 1.000 14.540  0 313 VAL A C   1 ? 
ATOM   2458 O  O   . VAL A 1 313 ? 44.711 14.796  33.237 1.000 15.752  0 313 VAL A O   1 ? 
ATOM   2459 C  CB  . VAL A 1 313 ? 45.839 12.603  31.102 1.000 15.443  0 313 VAL A CB  1 ? 
ATOM   2460 C  CG1 . VAL A 1 313 ? 44.830 13.498  30.416 1.000 16.066  0 313 VAL A CG1 1 ? 
ATOM   2461 C  CG2 . VAL A 1 313 ? 46.985 12.250  30.159 1.000 15.043  0 313 VAL A CG2 1 ? 
ATOM   2462 N  N   . LEU A 1 314 ? 44.749 12.745  34.152 1.000 14.157  0 314 LEU A N   1 ? 
ATOM   2463 C  CA  . LEU A 1 314 ? 43.666 13.039  35.086 1.000 13.928  0 314 LEU A CA  1 ? 
ATOM   2464 C  C   . LEU A 1 314 ? 44.084 14.134  36.067 1.000 14.154  0 314 LEU A C   1 ? 
ATOM   2465 O  O   . LEU A 1 314 ? 43.239 14.919  36.521 1.000 17.959  0 314 LEU A O   1 ? 
ATOM   2466 C  CB  . LEU A 1 314 ? 43.260 11.778  35.849 1.000 15.385  0 314 LEU A CB  1 ? 
ATOM   2467 C  CG  . LEU A 1 314 ? 42.620 10.674  35.003 1.000 15.109  0 314 LEU A CG  1 ? 
ATOM   2468 C  CD1 . LEU A 1 314 ? 42.281 9.488   35.935 1.000 15.420  0 314 LEU A CD1 1 ? 
ATOM   2469 C  CD2 . LEU A 1 314 ? 41.414 11.144  34.179 1.000 18.473  0 314 LEU A CD2 1 ? 
ATOM   2470 N  N   . CYS A 1 315 ? 45.387 14.181  36.388 1.000 15.040  0 315 CYS A N   1 ? 
ATOM   2471 C  CA  . CYS A 1 315 ? 45.900 15.230  37.252 1.000 14.742  0 315 CYS A CA  1 ? 
ATOM   2472 C  C   . CYS A 1 315 ? 45.953 16.578  36.535 1.000 18.486  0 315 CYS A C   1 ? 
ATOM   2473 O  O   . CYS A 1 315 ? 45.723 17.624  37.126 1.000 22.347  0 315 CYS A O   1 ? 
ATOM   2474 C  CB  . CYS A 1 315 ? 47.285 14.816  37.703 1.000 14.885  0 315 CYS A CB  1 ? 
ATOM   2475 S  SG  . CYS A 1 315 ? 48.024 15.912  38.925 1.000 17.270  0 315 CYS A SG  1 ? 
ATOM   2476 N  N   . GLY A 1 316 ? 46.279 16.566  35.256 1.000 19.959  0 316 GLY A N   1 ? 
ATOM   2477 C  CA  . GLY A 1 316 ? 46.535 17.803  34.534 1.000 25.073  0 316 GLY A CA  1 ? 
ATOM   2478 C  C   . GLY A 1 316 ? 47.947 18.293  34.834 1.000 32.164  0 316 GLY A C   1 ? 
ATOM   2479 O  O   . GLY A 1 316 ? 48.494 19.012  33.952 1.000 39.429  0 316 GLY A O   1 ? 
HETATM 2480 CA CA  . CA  B 2 .   ? 44.585 -6.092  20.284 1.000 21.963  0 401 CA  A CA  1 ? 
HETATM 2481 S  S   . SO4 C 3 .   ? 36.773 -3.881  11.811 1.000 36.977  0 402 SO4 A S   1 ? 
HETATM 2482 O  O1  . SO4 C 3 .   ? 37.206 -5.241  12.086 1.000 37.398  0 402 SO4 A O1  1 ? 
HETATM 2483 O  O2  . SO4 C 3 .   ? 36.218 -3.270  12.991 1.000 33.176  0 402 SO4 A O2  1 ? 
HETATM 2484 O  O3  . SO4 C 3 .   ? 37.869 -3.066  11.359 1.000 36.795  0 402 SO4 A O3  1 ? 
HETATM 2485 O  O4  . SO4 C 3 .   ? 35.735 -3.946  10.801 1.000 41.977  0 402 SO4 A O4  1 ? 
HETATM 2486 S  S   . SO4 D 3 .   ? 40.527 -8.446  16.523 1.000 70.783  0 403 SO4 A S   1 ? 
HETATM 2487 O  O1  . SO4 D 3 .   ? 40.065 -9.295  17.590 1.000 67.009  0 403 SO4 A O1  1 ? 
HETATM 2488 O  O2  . SO4 D 3 .   ? 40.758 -7.133  17.040 1.000 63.666  0 403 SO4 A O2  1 ? 
HETATM 2489 O  O3  . SO4 D 3 .   ? 41.760 -8.962  15.981 1.000 68.926  0 403 SO4 A O3  1 ? 
HETATM 2490 O  O4  . SO4 D 3 .   ? 39.527 -8.403  15.481 1.000 63.657  0 403 SO4 A O4  1 ? 
HETATM 2491 S  S   . SO4 E 3 .   ? 48.930 23.936  33.930 1.000 42.623  0 404 SO4 A S   1 ? 
HETATM 2492 O  O1  . SO4 E 3 .   ? 49.415 22.848  34.745 1.000 49.615  0 404 SO4 A O1  1 ? 
HETATM 2493 O  O2  . SO4 E 3 .   ? 49.543 25.161  34.364 1.000 39.685  0 404 SO4 A O2  1 ? 
HETATM 2494 O  O3  . SO4 E 3 .   ? 49.225 23.667  32.524 1.000 31.060  0 404 SO4 A O3  1 ? 
HETATM 2495 O  O4  . SO4 E 3 .   ? 47.494 24.031  34.088 1.000 52.952  0 404 SO4 A O4  1 ? 
HETATM 2496 S  S   . SO4 F 3 .   ? 61.231 7.806   35.199 1.000 58.564  0 405 SO4 A S   1 ? 
HETATM 2497 O  O1  . SO4 F 3 .   ? 60.722 8.070   36.516 1.000 60.942  0 405 SO4 A O1  1 ? 
HETATM 2498 O  O2  . SO4 F 3 .   ? 61.005 8.950   34.352 1.000 59.325  0 405 SO4 A O2  1 ? 
HETATM 2499 O  O3  . SO4 F 3 .   ? 62.635 7.538   35.297 1.000 61.583  0 405 SO4 A O3  1 ? 
HETATM 2500 O  O4  . SO4 F 3 .   ? 60.563 6.658   34.640 1.000 60.273  0 405 SO4 A O4  1 ? 
HETATM 2501 O  O   . HOH G 4 .   ? 29.797 -2.148  27.040 1.000 16.291  0 501 HOH A O   1 ? 
HETATM 2502 O  O   . HOH G 4 .   ? 43.018 -7.626  20.667 1.000 34.394  0 502 HOH A O   1 ? 
HETATM 2503 O  O   . HOH G 4 .   ? 32.121 18.881  21.319 1.000 26.500  0 503 HOH A O   1 ? 
HETATM 2504 O  O   . HOH G 4 .   ? 42.077 -7.779  31.135 1.000 17.695  0 504 HOH A O   1 ? 
HETATM 2505 O  O   . HOH G 4 .   ? 19.591 15.340  42.262 1.000 30.120  0 505 HOH A O   1 ? 
HETATM 2506 O  O   . HOH G 4 .   ? 54.878 5.496   33.327 1.000 64.661  0 506 HOH A O   1 ? 
HETATM 2507 O  O   . HOH G 4 .   ? 20.741 4.325   52.128 1.000 28.409  0 507 HOH A O   1 ? 
HETATM 2508 O  O   . HOH G 4 .   ? 34.753 -0.455  40.964 1.000 29.762  0 508 HOH A O   1 ? 
HETATM 2509 O  O   . HOH G 4 .   ? 55.610 15.120  53.603 1.000 29.397  0 509 HOH A O   1 ? 
HETATM 2510 O  O   . HOH G 4 .   ? 20.953 10.899  51.414 1.000 33.705  0 510 HOH A O   1 ? 
HETATM 2511 O  O   . HOH G 4 .   ? 35.296 20.283  46.144 1.000 32.002  0 511 HOH A O   1 ? 
HETATM 2512 O  O   . HOH G 4 .   ? 23.333 20.194  71.708 1.000 30.085  0 512 HOH A O   1 ? 
HETATM 2513 O  O   . HOH G 4 .   ? 35.874 17.368  73.458 1.000 25.384  0 513 HOH A O   1 ? 
HETATM 2514 O  O   . HOH G 4 .   ? 36.360 12.106  33.878 1.000 23.347  0 514 HOH A O   1 ? 
HETATM 2515 O  O   . HOH G 4 .   ? 54.750 1.754   46.085 1.000 38.194  0 515 HOH A O   1 ? 
HETATM 2516 O  O   . HOH G 4 .   ? 32.358 10.590  37.000 1.000 28.173  0 516 HOH A O   1 ? 
HETATM 2517 O  O   . HOH G 4 .   ? 44.679 -1.535  42.139 1.000 30.060  0 517 HOH A O   1 ? 
HETATM 2518 O  O   . HOH G 4 .   ? 24.610 17.253  45.749 1.000 24.234  0 518 HOH A O   1 ? 
HETATM 2519 O  O   . HOH G 4 .   ? 22.788 18.827  51.891 1.000 30.920  0 519 HOH A O   1 ? 
HETATM 2520 O  O   . HOH G 4 .   ? 21.436 21.567  61.644 1.000 23.564  0 520 HOH A O   1 ? 
HETATM 2521 O  O   . HOH G 4 .   ? 41.716 19.100  59.449 1.000 30.550  0 521 HOH A O   1 ? 
HETATM 2522 O  O   . HOH G 4 .   ? 47.017 -5.131  25.447 1.000 19.111  0 522 HOH A O   1 ? 
HETATM 2523 O  O   . HOH G 4 .   ? 22.481 5.613   38.538 1.000 25.238  0 523 HOH A O   1 ? 
HETATM 2524 O  O   . HOH G 4 .   ? 32.486 -7.858  53.952 1.000 34.766  0 524 HOH A O   1 ? 
HETATM 2525 O  O   . HOH G 4 .   ? 39.703 9.849   58.182 1.000 27.561  0 525 HOH A O   1 ? 
HETATM 2526 O  O   . HOH G 4 .   ? 38.192 23.877  35.904 1.000 28.020  0 526 HOH A O   1 ? 
HETATM 2527 O  O   . HOH G 4 .   ? 19.947 14.736  54.400 1.000 32.053  0 527 HOH A O   1 ? 
HETATM 2528 O  O   . HOH G 4 .   ? 39.450 9.228   55.447 1.000 18.865  0 528 HOH A O   1 ? 
HETATM 2529 O  O   . HOH G 4 .   ? 48.901 -5.853  15.067 1.000 27.169  0 529 HOH A O   1 ? 
HETATM 2530 O  O   . HOH G 4 .   ? 28.138 -6.055  62.014 1.000 23.150  0 530 HOH A O   1 ? 
HETATM 2531 O  O   . HOH G 4 .   ? 32.009 20.700  52.154 1.000 33.256  0 531 HOH A O   1 ? 
HETATM 2532 O  O   . HOH G 4 .   ? 29.653 -4.835  41.179 1.000 26.569  0 532 HOH A O   1 ? 
HETATM 2533 O  O   . HOH G 4 .   ? 27.994 12.581  53.665 1.000 20.432  0 533 HOH A O   1 ? 
HETATM 2534 O  O   . HOH G 4 .   ? 35.852 12.756  37.534 1.000 23.925  0 534 HOH A O   1 ? 
HETATM 2535 O  O   . HOH G 4 .   ? 44.320 -1.780  14.061 1.000 28.182  0 535 HOH A O   1 ? 
HETATM 2536 O  O   . HOH G 4 .   ? 41.295 17.649  73.433 1.000 30.295  0 536 HOH A O   1 ? 
HETATM 2537 O  O   . HOH G 4 .   ? 42.488 0.495   49.643 1.000 26.934  0 537 HOH A O   1 ? 
HETATM 2538 O  O   . HOH G 4 .   ? 59.521 10.396  50.593 1.000 30.214  0 538 HOH A O   1 ? 
HETATM 2539 O  O   . HOH G 4 .   ? 58.607 12.558  41.178 1.000 23.420  0 539 HOH A O   1 ? 
HETATM 2540 O  O   . HOH G 4 .   ? 55.112 4.513   47.966 1.000 25.607  0 540 HOH A O   1 ? 
HETATM 2541 O  O   . HOH G 4 .   ? 53.608 12.535  56.523 1.000 34.435  0 541 HOH A O   1 ? 
HETATM 2542 O  O   . HOH G 4 .   ? 41.143 1.923   51.709 1.000 28.008  0 542 HOH A O   1 ? 
HETATM 2543 O  O   . HOH G 4 .   ? 25.931 10.669  28.089 1.000 20.291  0 543 HOH A O   1 ? 
HETATM 2544 O  O   . HOH G 4 .   ? 20.732 9.691   58.741 1.000 28.327  0 544 HOH A O   1 ? 
HETATM 2545 O  O   . HOH G 4 .   ? 36.330 -8.423  23.655 1.000 28.998  0 545 HOH A O   1 ? 
HETATM 2546 O  O   . HOH G 4 .   ? 24.282 11.675  58.660 1.000 20.548  0 546 HOH A O   1 ? 
HETATM 2547 O  O   . HOH G 4 .   ? 43.679 4.537   16.901 1.000 22.679  0 547 HOH A O   1 ? 
HETATM 2548 O  O   . HOH G 4 .   ? 38.430 1.513   40.652 1.000 20.418  0 548 HOH A O   1 ? 
HETATM 2549 O  O   . HOH G 4 .   ? 54.687 6.291   32.167 1.000 16.907  0 549 HOH A O   1 ? 
HETATM 2550 O  O   . HOH G 4 .   ? 37.578 0.157   37.688 1.000 28.463  0 550 HOH A O   1 ? 
HETATM 2551 O  O   . HOH G 4 .   ? 36.977 5.398   69.894 1.000 30.387  0 551 HOH A O   1 ? 
HETATM 2552 O  O   . HOH G 4 .   ? 46.101 21.697  34.278 1.000 30.632  0 552 HOH A O   1 ? 
HETATM 2553 O  O   . HOH G 4 .   ? 36.090 9.399   46.114 1.000 19.765  0 553 HOH A O   1 ? 
HETATM 2554 O  O   . HOH G 4 .   ? 40.118 1.744   48.539 1.000 22.080  0 554 HOH A O   1 ? 
HETATM 2555 O  O   . HOH G 4 .   ? 50.993 6.842   53.710 1.000 22.540  0 555 HOH A O   1 ? 
HETATM 2556 O  O   . HOH G 4 .   ? 39.381 1.455   43.608 1.000 19.605  0 556 HOH A O   1 ? 
HETATM 2557 O  O   . HOH G 4 .   ? 17.900 3.770   48.810 1.000 32.859  0 557 HOH A O   1 ? 
HETATM 2558 O  O   . HOH G 4 .   ? 59.322 21.024  49.188 1.000 32.959  0 558 HOH A O   1 ? 
HETATM 2559 O  O   . HOH G 4 .   ? 48.976 25.775  46.107 1.000 29.394  0 559 HOH A O   1 ? 
HETATM 2560 O  O   . HOH G 4 .   ? 18.788 -9.338  49.163 1.000 21.142  0 560 HOH A O   1 ? 
HETATM 2561 O  O   . HOH G 4 .   ? 33.594 7.121   36.475 1.000 17.263  0 561 HOH A O   1 ? 
HETATM 2562 O  O   . HOH G 4 .   ? 42.523 5.667   63.599 1.000 35.887  0 562 HOH A O   1 ? 
HETATM 2563 O  O   . HOH G 4 .   ? 52.068 -1.382  47.358 1.000 32.760  0 563 HOH A O   1 ? 
HETATM 2564 O  O   . HOH G 4 .   ? 45.136 28.869  74.762 1.000 26.520  0 564 HOH A O   1 ? 
HETATM 2565 O  O   . HOH G 4 .   ? 38.406 17.562  26.967 1.000 25.115  0 565 HOH A O   1 ? 
HETATM 2566 O  O   . HOH G 4 .   ? 45.300 15.232  69.448 1.000 32.049  0 566 HOH A O   1 ? 
HETATM 2567 O  O   . HOH G 4 .   ? 15.087 13.153  43.052 1.000 20.843  0 567 HOH A O   1 ? 
HETATM 2568 O  O   . HOH G 4 .   ? 46.114 -7.826  21.441 1.000 23.936  0 568 HOH A O   1 ? 
HETATM 2569 O  O   . HOH G 4 .   ? 45.618 5.035   51.582 1.000 21.356  0 569 HOH A O   1 ? 
HETATM 2570 O  O   . HOH G 4 .   ? 31.848 16.112  13.891 1.000 24.305  0 570 HOH A O   1 ? 
HETATM 2571 O  O   . HOH G 4 .   ? 41.529 16.060  30.012 1.000 23.833  0 571 HOH A O   1 ? 
HETATM 2572 O  O   . HOH G 4 .   ? 38.505 1.784   13.139 1.000 25.112  0 572 HOH A O   1 ? 
HETATM 2573 O  O   . HOH G 4 .   ? 35.028 9.229   35.331 1.000 24.506  0 573 HOH A O   1 ? 
HETATM 2574 O  O   . HOH G 4 .   ? 38.503 -4.019  19.459 1.000 22.476  0 574 HOH A O   1 ? 
HETATM 2575 O  O   . HOH G 4 .   ? 35.892 -8.754  28.299 1.000 27.015  0 575 HOH A O   1 ? 
HETATM 2576 O  O   . HOH G 4 .   ? 24.504 7.367   24.735 1.000 28.054  0 576 HOH A O   1 ? 
HETATM 2577 O  O   . HOH G 4 .   ? 30.344 13.873  32.800 1.000 21.825  0 577 HOH A O   1 ? 
HETATM 2578 O  O   . HOH G 4 .   ? 27.980 -7.322  51.561 1.000 34.918  0 578 HOH A O   1 ? 
HETATM 2579 O  O   . HOH G 4 .   ? 31.951 8.547   40.890 1.000 16.368  0 579 HOH A O   1 ? 
HETATM 2580 O  O   . HOH G 4 .   ? 37.788 -2.065  48.157 1.000 26.797  0 580 HOH A O   1 ? 
HETATM 2581 O  O   . HOH G 4 .   ? 42.334 -4.593  36.824 1.000 25.738  0 581 HOH A O   1 ? 
HETATM 2582 O  O   . HOH G 4 .   ? 50.557 11.420  30.602 1.000 22.472  0 582 HOH A O   1 ? 
HETATM 2583 O  O   . HOH G 4 .   ? 25.859 4.562   29.666 1.000 25.867  0 583 HOH A O   1 ? 
HETATM 2584 O  O   . HOH G 4 .   ? 31.726 -0.655  35.296 1.000 31.394  0 584 HOH A O   1 ? 
HETATM 2585 O  O   . HOH G 4 .   ? 37.631 23.454  65.810 1.000 16.892  0 585 HOH A O   1 ? 
HETATM 2586 O  O   . HOH G 4 .   ? 44.376 7.488   51.599 1.000 17.595  0 586 HOH A O   1 ? 
HETATM 2587 O  O   . HOH G 4 .   ? 24.826 24.420  55.179 1.000 20.348  0 587 HOH A O   1 ? 
HETATM 2588 O  O   . HOH G 4 .   ? 36.572 25.428  58.926 1.000 29.048  0 588 HOH A O   1 ? 
HETATM 2589 O  O   . HOH G 4 .   ? 21.412 25.904  63.090 1.000 26.274  0 589 HOH A O   1 ? 
HETATM 2590 O  O   . HOH G 4 .   ? 32.371 31.153  67.807 1.000 27.223  0 590 HOH A O   1 ? 
HETATM 2591 O  O   . HOH G 4 .   ? 39.858 -6.351  23.066 1.000 28.848  0 591 HOH A O   1 ? 
HETATM 2592 O  O   . HOH G 4 .   ? 23.019 5.129   62.954 1.000 25.586  0 592 HOH A O   1 ? 
HETATM 2593 O  O   . HOH G 4 .   ? 34.942 21.990  36.762 1.000 29.580  0 593 HOH A O   1 ? 
HETATM 2594 O  O   . HOH G 4 .   ? 39.308 6.719   54.310 1.000 24.186  0 594 HOH A O   1 ? 
HETATM 2595 O  O   . HOH G 4 .   ? 26.273 7.922   20.801 1.000 25.094  0 595 HOH A O   1 ? 
HETATM 2596 O  O   . HOH G 4 .   ? 24.117 1.872   19.724 1.000 22.023  0 596 HOH A O   1 ? 
HETATM 2597 O  O   . HOH G 4 .   ? 33.751 -2.246  62.118 1.000 27.188  0 597 HOH A O   1 ? 
HETATM 2598 O  O   . HOH G 4 .   ? 49.838 20.073  43.098 1.000 15.393  0 598 HOH A O   1 ? 
HETATM 2599 O  O   . HOH G 4 .   ? 36.281 -0.500  46.445 1.000 22.539  0 599 HOH A O   1 ? 
HETATM 2600 O  O   . HOH G 4 .   ? 29.961 -0.233  23.857 1.000 16.200  0 600 HOH A O   1 ? 
HETATM 2601 O  O   . HOH G 4 .   ? 57.066 1.922   48.578 1.000 36.448  0 601 HOH A O   1 ? 
HETATM 2602 O  O   . HOH G 4 .   ? 36.202 13.426  18.867 1.000 18.825  0 602 HOH A O   1 ? 
HETATM 2603 O  O   . HOH G 4 .   ? 22.068 -6.304  38.078 1.000 32.488  0 603 HOH A O   1 ? 
HETATM 2604 O  O   . HOH G 4 .   ? 37.213 25.955  63.411 1.000 26.516  0 604 HOH A O   1 ? 
HETATM 2605 O  O   . HOH G 4 .   ? 41.443 -1.719  49.070 1.000 29.315  0 605 HOH A O   1 ? 
HETATM 2606 O  O   . HOH G 4 .   ? 26.794 -3.192  39.150 1.000 29.926  0 606 HOH A O   1 ? 
HETATM 2607 O  O   . HOH G 4 .   ? 19.834 -5.164  38.448 1.000 26.354  0 607 HOH A O   1 ? 
HETATM 2608 O  O   . HOH G 4 .   ? 34.261 21.503  50.462 1.000 30.260  0 608 HOH A O   1 ? 
HETATM 2609 O  O   . HOH G 4 .   ? 25.482 -2.709  15.620 1.000 18.427  0 609 HOH A O   1 ? 
HETATM 2610 O  O   . HOH G 4 .   ? 21.552 9.986   62.743 1.000 43.732  0 610 HOH A O   1 ? 
HETATM 2611 O  O   . HOH G 4 .   ? 30.571 -0.646  26.956 1.000 25.699  0 611 HOH A O   1 ? 
HETATM 2612 O  O   . HOH G 4 .   ? 32.959 12.330  43.657 1.000 28.657  0 612 HOH A O   1 ? 
HETATM 2613 O  O   . HOH G 4 .   ? 25.782 13.693  55.092 1.000 25.942  0 613 HOH A O   1 ? 
HETATM 2614 O  O   . HOH G 4 .   ? 19.117 12.421  45.043 1.000 24.662  0 614 HOH A O   1 ? 
HETATM 2615 O  O   . HOH G 4 .   ? 27.328 1.069   32.735 1.000 29.701  0 615 HOH A O   1 ? 
HETATM 2616 O  O   . HOH G 4 .   ? 20.104 31.167  59.204 1.000 32.544  0 616 HOH A O   1 ? 
HETATM 2617 O  O   . HOH G 4 .   ? 31.156 15.052  46.640 1.000 25.478  0 617 HOH A O   1 ? 
HETATM 2618 O  O   . HOH G 4 .   ? 58.003 5.985   39.084 1.000 28.888  0 618 HOH A O   1 ? 
HETATM 2619 O  O   . HOH G 4 .   ? 34.173 -7.419  15.137 1.000 28.180  0 619 HOH A O   1 ? 
HETATM 2620 O  O   . HOH G 4 .   ? 31.198 15.440  55.837 1.000 24.284  0 620 HOH A O   1 ? 
HETATM 2621 O  O   . HOH G 4 .   ? 48.787 -1.521  34.789 1.000 23.651  0 621 HOH A O   1 ? 
HETATM 2622 O  O   . HOH G 4 .   ? 30.826 30.143  65.658 1.000 30.086  0 622 HOH A O   1 ? 
HETATM 2623 O  O   . HOH G 4 .   ? 31.922 -4.009  42.370 1.000 22.682  0 623 HOH A O   1 ? 
HETATM 2624 O  O   . HOH G 4 .   ? 20.112 0.767   49.348 1.000 16.896  0 624 HOH A O   1 ? 
HETATM 2625 O  O   . HOH G 4 .   ? 50.577 0.356   33.383 1.000 24.507  0 625 HOH A O   1 ? 
HETATM 2626 O  O   . HOH G 4 .   ? 49.247 -2.972  37.132 1.000 30.940  0 626 HOH A O   1 ? 
HETATM 2627 O  O   . HOH G 4 .   ? 53.020 1.682   38.839 1.000 22.691  0 627 HOH A O   1 ? 
HETATM 2628 O  O   . HOH G 4 .   ? 29.655 -7.262  14.619 1.000 33.954  0 628 HOH A O   1 ? 
HETATM 2629 O  O   . HOH G 4 .   ? 46.037 3.168   16.902 1.000 30.060  0 629 HOH A O   1 ? 
HETATM 2630 O  O   . HOH G 4 .   ? 57.730 7.851   50.024 1.000 26.761  0 630 HOH A O   1 ? 
HETATM 2631 O  O   . HOH G 4 .   ? 44.513 -7.850  35.176 1.000 31.419  0 631 HOH A O   1 ? 
HETATM 2632 O  O   . HOH G 4 .   ? 36.356 2.198   65.828 1.000 25.952  0 632 HOH A O   1 ? 
HETATM 2633 O  O   . HOH G 4 .   ? 27.551 9.357   34.527 1.000 25.520  0 633 HOH A O   1 ? 
HETATM 2634 O  O   . HOH G 4 .   ? 32.735 1.498   69.017 1.000 30.718  0 634 HOH A O   1 ? 
HETATM 2635 O  O   . HOH G 4 .   ? 45.157 -1.052  46.619 1.000 28.342  0 635 HOH A O   1 ? 
HETATM 2636 O  O   . HOH G 4 .   ? 33.572 1.355   66.327 1.000 27.282  0 636 HOH A O   1 ? 
HETATM 2637 O  O   . HOH G 4 .   ? 25.745 10.264  43.443 1.000 26.959  0 637 HOH A O   1 ? 
HETATM 2638 O  O   . HOH G 4 .   ? 44.255 14.189  23.161 1.000 29.650  0 638 HOH A O   1 ? 
HETATM 2639 O  O   . HOH G 4 .   ? 27.500 32.471  69.813 1.000 33.594  0 639 HOH A O   1 ? 
HETATM 2640 O  O   . HOH G 4 .   ? 27.769 -3.837  66.294 1.000 32.992  0 640 HOH A O   1 ? 
HETATM 2641 O  O   . HOH G 4 .   ? 37.926 0.277   64.695 1.000 32.630  0 641 HOH A O   1 ? 
HETATM 2642 O  O   . HOH G 4 .   ? 28.957 16.743  28.775 1.000 27.495  0 642 HOH A O   1 ? 
HETATM 2643 O  O   . HOH G 4 .   ? 22.527 5.776   71.753 1.000 34.752  0 643 HOH A O   1 ? 
HETATM 2644 O  O   . HOH G 4 .   ? 50.005 18.799  40.241 1.000 16.328  0 644 HOH A O   1 ? 
HETATM 2645 O  O   . HOH G 4 .   ? 25.797 8.506   36.802 1.000 19.687  0 645 HOH A O   1 ? 
HETATM 2646 O  O   . HOH G 4 .   ? 49.638 3.768   51.299 1.000 30.295  0 646 HOH A O   1 ? 
HETATM 2647 O  O   . HOH G 4 .   ? 39.778 19.719  55.302 1.000 23.083  0 647 HOH A O   1 ? 
HETATM 2648 O  O   . HOH G 4 .   ? 47.113 -2.997  29.949 1.000 25.462  0 648 HOH A O   1 ? 
HETATM 2649 O  O   . HOH G 4 .   ? 29.120 14.136  55.893 1.000 33.305  0 649 HOH A O   1 ? 
HETATM 2650 O  O   . HOH G 4 .   ? 55.832 15.928  50.916 1.000 25.492  0 650 HOH A O   1 ? 
HETATM 2651 O  O   . HOH G 4 .   ? 20.017 1.519   52.013 1.000 26.434  0 651 HOH A O   1 ? 
HETATM 2652 O  O   . HOH G 4 .   ? 31.869 17.962  45.527 1.000 34.374  0 652 HOH A O   1 ? 
HETATM 2653 O  O   . HOH G 4 .   ? 24.996 5.632   37.176 1.000 20.464  0 653 HOH A O   1 ? 
HETATM 2654 O  O   . HOH G 4 .   ? 42.159 10.163  54.671 1.000 32.889  0 654 HOH A O   1 ? 
HETATM 2655 O  O   . HOH G 4 .   ? 39.863 17.740  29.326 1.000 25.375  0 655 HOH A O   1 ? 
HETATM 2656 O  O   . HOH G 4 .   ? 39.610 -0.664  12.629 1.000 28.841  0 656 HOH A O   1 ? 
HETATM 2657 O  O   . HOH G 4 .   ? 62.651 11.094  32.494 1.000 30.103  0 657 HOH A O   1 ? 
HETATM 2658 O  O   . HOH G 4 .   ? 37.509 -0.562  9.171  1.000 53.736  0 658 HOH A O   1 ? 
HETATM 2659 O  O   . HOH G 4 .   ? 23.961 -0.539  18.162 1.000 25.897  0 659 HOH A O   1 ? 
HETATM 2660 O  O   . HOH G 4 .   ? 37.381 15.822  20.309 1.000 34.203  0 660 HOH A O   1 ? 
HETATM 2661 O  O   . HOH G 4 .   ? 56.210 10.456  33.362 1.000 25.152  0 661 HOH A O   1 ? 
HETATM 2662 O  O   . HOH G 4 .   ? 19.073 24.910  70.144 1.000 48.337  0 662 HOH A O   1 ? 
HETATM 2663 O  O   . HOH G 4 .   ? 54.569 9.085   31.798 1.000 27.860  0 663 HOH A O   1 ? 
HETATM 2664 O  O   . HOH G 4 .   ? 25.462 27.402  52.048 1.000 32.746  0 664 HOH A O   1 ? 
HETATM 2665 O  O   . HOH G 4 .   ? 45.220 24.599  74.833 1.000 33.006  0 665 HOH A O   1 ? 
HETATM 2666 O  O   . HOH G 4 .   ? 33.470 8.882   38.586 1.000 15.675  0 666 HOH A O   1 ? 
HETATM 2667 O  O   . HOH G 4 .   ? 24.316 8.525   27.147 1.000 26.981  0 667 HOH A O   1 ? 
HETATM 2668 O  O   . HOH G 4 .   ? 43.920 7.978   54.021 1.000 32.127  0 668 HOH A O   1 ? 
HETATM 2669 O  O   . HOH G 4 .   ? 25.473 10.713  30.763 1.000 34.431  0 669 HOH A O   1 ? 
HETATM 2670 O  O   . HOH G 4 .   ? 53.177 10.713  30.495 1.000 30.997  0 670 HOH A O   1 ? 
HETATM 2671 O  O   . HOH G 4 .   ? 24.175 3.629   35.266 1.000 31.067  0 671 HOH A O   1 ? 
# 
