data_9G8F
# 
_entry.id   9G8F 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9G8F         pdb_00009g8f 10.2210/pdb9g8f/pdb 
WWPDB D_1292140546 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-25 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9G8F 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB . 9G88 unspecified 
PDB . 9G89 unspecified 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 jacek.plewka@uj.edu.pl       Jacek     Plewka         ? 'principal investigator/group leader' 0000-0002-0307-0907 
3 lukas.schober@tugraz.at      Lucas     Schorber       ? 'principal investigator/group leader' 0000-0001-6546-6555 
4 k.magiera@uj.edu.pl          Katarzyna Magiera-Mularz ? 'principal investigator/group leader' 0000-0002-4826-6380 
5 florian.rudroff@tuwien.ac.at Florian   Rudroff        ? 'principal investigator/group leader' 0000-0002-6680-8200 
6 margit.winkler@tugraz.at     Margit    Winkler        ? 'principal investigator/group leader' 0000-0002-0754-9704 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Plewka, J.'         1 0000-0002-0307-0907 
'Schorber, L.'       2 0000-0001-6546-6555 
'Magiera-Mularz, K.' 3 0000-0002-4826-6380 
'Rudroff, F.'        4 0000-0002-6680-8200 
'Winkler, M.'        5 0000-0002-0754-9704 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Jacs Au' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2691-3704 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'structure of carotenoid cleavage oxygenase from Moesziomyces aphidis in apo and product bound forms' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/jacsau.5c00456 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Schorber, L.'       1 ? 
primary 'Plewka, J.'         2 ? 
primary 'Magiera-Mularz, K.' 3 ? 
primary 'Rudroff, F.'        4 ? 
primary 'Winkler, M.'        5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Lignostilbene dioxygenase' 62905.562 2   ? ? ? 'Aromatic dioxygenase' 
2 non-polymer syn ortho-vanillin              152.147   2   ? ? ? ?                      
3 non-polymer syn 'FE (II) ION'               55.845    2   ? ? ? ?                      
4 water       nat water                       18.015    996 ? ? ? ?                      
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Carotenoid cleavage oxygenase, Aromatic dioxygenase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MWSHPQFEKAPTATQEPVPVPVTSKAAPSHGYVHPTDILPSGWPTATDLSGGAQPRRFEGTIFDVMTRGTIPKELHGTFY
RIMPDYAQPPTYYKGGELNAPIDGDGTVAAFRFKDGKVDYRQRFVETDRFKVERRARKSMYGLYRNPYTHHPCVRQTVES
TANTNVVMHAGRFLAMKENGNAYEMDPHTLKTLGYNPFNLPSKTMTAHPKQCSVTGNLVGFGYEAKGLATKDVYYFEVDP
SGKVVRDLWLEAPWCAFIHDCALTPNYLVLMLWPFEANLERMKAGGHHWAYDYTKPITWITIPRGAKSKDEVKYWHWKNG
MPIHTASGFEDEQGRIIIDSSLVHGNAFPFFPPDSDEQKKKQEADGTPKAQFVRWTIDPRKDNNEQLPDPEVILDTPSEF
PQIDNRFMGVEYSSAFINVFVPDRSDGNKNVFQGLNGLAHYKRKEGTTEWYYAGDNCLIQEPVFSPRSKDAPEGDGFVLA
IVDRLDLNRSEVVVIDTRDFTKAVAAVQLPFAIRSGIHGQWIPGEVTPDFETKGLVDLPKEEHWAPLSQSPYDPDA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MWSHPQFEKAPTATQEPVPVPVTSKAAPSHGYVHPTDILPSGWPTATDLSGGAQPRRFEGTIFDVMTRGTIPKELHGTFY
RIMPDYAQPPTYYKGGELNAPIDGDGTVAAFRFKDGKVDYRQRFVETDRFKVERRARKSMYGLYRNPYTHHPCVRQTVES
TANTNVVMHAGRFLAMKENGNAYEMDPHTLKTLGYNPFNLPSKTMTAHPKQCSVTGNLVGFGYEAKGLATKDVYYFEVDP
SGKVVRDLWLEAPWCAFIHDCALTPNYLVLMLWPFEANLERMKAGGHHWAYDYTKPITWITIPRGAKSKDEVKYWHWKNG
MPIHTASGFEDEQGRIIIDSSLVHGNAFPFFPPDSDEQKKKQEADGTPKAQFVRWTIDPRKDNNEQLPDPEVILDTPSEF
PQIDNRFMGVEYSSAFINVFVPDRSDGNKNVFQGLNGLAHYKRKEGTTEWYYAGDNCLIQEPVFSPRSKDAPEGDGFVLA
IVDRLDLNRSEVVVIDTRDFTKAVAAVQLPFAIRSGIHGQWIPGEVTPDFETKGLVDLPKEEHWAPLSQSPYDPDA
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 ortho-vanillin V9L 
3 'FE (II) ION'  FE2 
4 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   TRP n 
1 3   SER n 
1 4   HIS n 
1 5   PRO n 
1 6   GLN n 
1 7   PHE n 
1 8   GLU n 
1 9   LYS n 
1 10  ALA n 
1 11  PRO n 
1 12  THR n 
1 13  ALA n 
1 14  THR n 
1 15  GLN n 
1 16  GLU n 
1 17  PRO n 
1 18  VAL n 
1 19  PRO n 
1 20  VAL n 
1 21  PRO n 
1 22  VAL n 
1 23  THR n 
1 24  SER n 
1 25  LYS n 
1 26  ALA n 
1 27  ALA n 
1 28  PRO n 
1 29  SER n 
1 30  HIS n 
1 31  GLY n 
1 32  TYR n 
1 33  VAL n 
1 34  HIS n 
1 35  PRO n 
1 36  THR n 
1 37  ASP n 
1 38  ILE n 
1 39  LEU n 
1 40  PRO n 
1 41  SER n 
1 42  GLY n 
1 43  TRP n 
1 44  PRO n 
1 45  THR n 
1 46  ALA n 
1 47  THR n 
1 48  ASP n 
1 49  LEU n 
1 50  SER n 
1 51  GLY n 
1 52  GLY n 
1 53  ALA n 
1 54  GLN n 
1 55  PRO n 
1 56  ARG n 
1 57  ARG n 
1 58  PHE n 
1 59  GLU n 
1 60  GLY n 
1 61  THR n 
1 62  ILE n 
1 63  PHE n 
1 64  ASP n 
1 65  VAL n 
1 66  MET n 
1 67  THR n 
1 68  ARG n 
1 69  GLY n 
1 70  THR n 
1 71  ILE n 
1 72  PRO n 
1 73  LYS n 
1 74  GLU n 
1 75  LEU n 
1 76  HIS n 
1 77  GLY n 
1 78  THR n 
1 79  PHE n 
1 80  TYR n 
1 81  ARG n 
1 82  ILE n 
1 83  MET n 
1 84  PRO n 
1 85  ASP n 
1 86  TYR n 
1 87  ALA n 
1 88  GLN n 
1 89  PRO n 
1 90  PRO n 
1 91  THR n 
1 92  TYR n 
1 93  TYR n 
1 94  LYS n 
1 95  GLY n 
1 96  GLY n 
1 97  GLU n 
1 98  LEU n 
1 99  ASN n 
1 100 ALA n 
1 101 PRO n 
1 102 ILE n 
1 103 ASP n 
1 104 GLY n 
1 105 ASP n 
1 106 GLY n 
1 107 THR n 
1 108 VAL n 
1 109 ALA n 
1 110 ALA n 
1 111 PHE n 
1 112 ARG n 
1 113 PHE n 
1 114 LYS n 
1 115 ASP n 
1 116 GLY n 
1 117 LYS n 
1 118 VAL n 
1 119 ASP n 
1 120 TYR n 
1 121 ARG n 
1 122 GLN n 
1 123 ARG n 
1 124 PHE n 
1 125 VAL n 
1 126 GLU n 
1 127 THR n 
1 128 ASP n 
1 129 ARG n 
1 130 PHE n 
1 131 LYS n 
1 132 VAL n 
1 133 GLU n 
1 134 ARG n 
1 135 ARG n 
1 136 ALA n 
1 137 ARG n 
1 138 LYS n 
1 139 SER n 
1 140 MET n 
1 141 TYR n 
1 142 GLY n 
1 143 LEU n 
1 144 TYR n 
1 145 ARG n 
1 146 ASN n 
1 147 PRO n 
1 148 TYR n 
1 149 THR n 
1 150 HIS n 
1 151 HIS n 
1 152 PRO n 
1 153 CYS n 
1 154 VAL n 
1 155 ARG n 
1 156 GLN n 
1 157 THR n 
1 158 VAL n 
1 159 GLU n 
1 160 SER n 
1 161 THR n 
1 162 ALA n 
1 163 ASN n 
1 164 THR n 
1 165 ASN n 
1 166 VAL n 
1 167 VAL n 
1 168 MET n 
1 169 HIS n 
1 170 ALA n 
1 171 GLY n 
1 172 ARG n 
1 173 PHE n 
1 174 LEU n 
1 175 ALA n 
1 176 MET n 
1 177 LYS n 
1 178 GLU n 
1 179 ASN n 
1 180 GLY n 
1 181 ASN n 
1 182 ALA n 
1 183 TYR n 
1 184 GLU n 
1 185 MET n 
1 186 ASP n 
1 187 PRO n 
1 188 HIS n 
1 189 THR n 
1 190 LEU n 
1 191 LYS n 
1 192 THR n 
1 193 LEU n 
1 194 GLY n 
1 195 TYR n 
1 196 ASN n 
1 197 PRO n 
1 198 PHE n 
1 199 ASN n 
1 200 LEU n 
1 201 PRO n 
1 202 SER n 
1 203 LYS n 
1 204 THR n 
1 205 MET n 
1 206 THR n 
1 207 ALA n 
1 208 HIS n 
1 209 PRO n 
1 210 LYS n 
1 211 GLN n 
1 212 CYS n 
1 213 SER n 
1 214 VAL n 
1 215 THR n 
1 216 GLY n 
1 217 ASN n 
1 218 LEU n 
1 219 VAL n 
1 220 GLY n 
1 221 PHE n 
1 222 GLY n 
1 223 TYR n 
1 224 GLU n 
1 225 ALA n 
1 226 LYS n 
1 227 GLY n 
1 228 LEU n 
1 229 ALA n 
1 230 THR n 
1 231 LYS n 
1 232 ASP n 
1 233 VAL n 
1 234 TYR n 
1 235 TYR n 
1 236 PHE n 
1 237 GLU n 
1 238 VAL n 
1 239 ASP n 
1 240 PRO n 
1 241 SER n 
1 242 GLY n 
1 243 LYS n 
1 244 VAL n 
1 245 VAL n 
1 246 ARG n 
1 247 ASP n 
1 248 LEU n 
1 249 TRP n 
1 250 LEU n 
1 251 GLU n 
1 252 ALA n 
1 253 PRO n 
1 254 TRP n 
1 255 CYS n 
1 256 ALA n 
1 257 PHE n 
1 258 ILE n 
1 259 HIS n 
1 260 ASP n 
1 261 CYS n 
1 262 ALA n 
1 263 LEU n 
1 264 THR n 
1 265 PRO n 
1 266 ASN n 
1 267 TYR n 
1 268 LEU n 
1 269 VAL n 
1 270 LEU n 
1 271 MET n 
1 272 LEU n 
1 273 TRP n 
1 274 PRO n 
1 275 PHE n 
1 276 GLU n 
1 277 ALA n 
1 278 ASN n 
1 279 LEU n 
1 280 GLU n 
1 281 ARG n 
1 282 MET n 
1 283 LYS n 
1 284 ALA n 
1 285 GLY n 
1 286 GLY n 
1 287 HIS n 
1 288 HIS n 
1 289 TRP n 
1 290 ALA n 
1 291 TYR n 
1 292 ASP n 
1 293 TYR n 
1 294 THR n 
1 295 LYS n 
1 296 PRO n 
1 297 ILE n 
1 298 THR n 
1 299 TRP n 
1 300 ILE n 
1 301 THR n 
1 302 ILE n 
1 303 PRO n 
1 304 ARG n 
1 305 GLY n 
1 306 ALA n 
1 307 LYS n 
1 308 SER n 
1 309 LYS n 
1 310 ASP n 
1 311 GLU n 
1 312 VAL n 
1 313 LYS n 
1 314 TYR n 
1 315 TRP n 
1 316 HIS n 
1 317 TRP n 
1 318 LYS n 
1 319 ASN n 
1 320 GLY n 
1 321 MET n 
1 322 PRO n 
1 323 ILE n 
1 324 HIS n 
1 325 THR n 
1 326 ALA n 
1 327 SER n 
1 328 GLY n 
1 329 PHE n 
1 330 GLU n 
1 331 ASP n 
1 332 GLU n 
1 333 GLN n 
1 334 GLY n 
1 335 ARG n 
1 336 ILE n 
1 337 ILE n 
1 338 ILE n 
1 339 ASP n 
1 340 SER n 
1 341 SER n 
1 342 LEU n 
1 343 VAL n 
1 344 HIS n 
1 345 GLY n 
1 346 ASN n 
1 347 ALA n 
1 348 PHE n 
1 349 PRO n 
1 350 PHE n 
1 351 PHE n 
1 352 PRO n 
1 353 PRO n 
1 354 ASP n 
1 355 SER n 
1 356 ASP n 
1 357 GLU n 
1 358 GLN n 
1 359 LYS n 
1 360 LYS n 
1 361 LYS n 
1 362 GLN n 
1 363 GLU n 
1 364 ALA n 
1 365 ASP n 
1 366 GLY n 
1 367 THR n 
1 368 PRO n 
1 369 LYS n 
1 370 ALA n 
1 371 GLN n 
1 372 PHE n 
1 373 VAL n 
1 374 ARG n 
1 375 TRP n 
1 376 THR n 
1 377 ILE n 
1 378 ASP n 
1 379 PRO n 
1 380 ARG n 
1 381 LYS n 
1 382 ASP n 
1 383 ASN n 
1 384 ASN n 
1 385 GLU n 
1 386 GLN n 
1 387 LEU n 
1 388 PRO n 
1 389 ASP n 
1 390 PRO n 
1 391 GLU n 
1 392 VAL n 
1 393 ILE n 
1 394 LEU n 
1 395 ASP n 
1 396 THR n 
1 397 PRO n 
1 398 SER n 
1 399 GLU n 
1 400 PHE n 
1 401 PRO n 
1 402 GLN n 
1 403 ILE n 
1 404 ASP n 
1 405 ASN n 
1 406 ARG n 
1 407 PHE n 
1 408 MET n 
1 409 GLY n 
1 410 VAL n 
1 411 GLU n 
1 412 TYR n 
1 413 SER n 
1 414 SER n 
1 415 ALA n 
1 416 PHE n 
1 417 ILE n 
1 418 ASN n 
1 419 VAL n 
1 420 PHE n 
1 421 VAL n 
1 422 PRO n 
1 423 ASP n 
1 424 ARG n 
1 425 SER n 
1 426 ASP n 
1 427 GLY n 
1 428 ASN n 
1 429 LYS n 
1 430 ASN n 
1 431 VAL n 
1 432 PHE n 
1 433 GLN n 
1 434 GLY n 
1 435 LEU n 
1 436 ASN n 
1 437 GLY n 
1 438 LEU n 
1 439 ALA n 
1 440 HIS n 
1 441 TYR n 
1 442 LYS n 
1 443 ARG n 
1 444 LYS n 
1 445 GLU n 
1 446 GLY n 
1 447 THR n 
1 448 THR n 
1 449 GLU n 
1 450 TRP n 
1 451 TYR n 
1 452 TYR n 
1 453 ALA n 
1 454 GLY n 
1 455 ASP n 
1 456 ASN n 
1 457 CYS n 
1 458 LEU n 
1 459 ILE n 
1 460 GLN n 
1 461 GLU n 
1 462 PRO n 
1 463 VAL n 
1 464 PHE n 
1 465 SER n 
1 466 PRO n 
1 467 ARG n 
1 468 SER n 
1 469 LYS n 
1 470 ASP n 
1 471 ALA n 
1 472 PRO n 
1 473 GLU n 
1 474 GLY n 
1 475 ASP n 
1 476 GLY n 
1 477 PHE n 
1 478 VAL n 
1 479 LEU n 
1 480 ALA n 
1 481 ILE n 
1 482 VAL n 
1 483 ASP n 
1 484 ARG n 
1 485 LEU n 
1 486 ASP n 
1 487 LEU n 
1 488 ASN n 
1 489 ARG n 
1 490 SER n 
1 491 GLU n 
1 492 VAL n 
1 493 VAL n 
1 494 VAL n 
1 495 ILE n 
1 496 ASP n 
1 497 THR n 
1 498 ARG n 
1 499 ASP n 
1 500 PHE n 
1 501 THR n 
1 502 LYS n 
1 503 ALA n 
1 504 VAL n 
1 505 ALA n 
1 506 ALA n 
1 507 VAL n 
1 508 GLN n 
1 509 LEU n 
1 510 PRO n 
1 511 PHE n 
1 512 ALA n 
1 513 ILE n 
1 514 ARG n 
1 515 SER n 
1 516 GLY n 
1 517 ILE n 
1 518 HIS n 
1 519 GLY n 
1 520 GLN n 
1 521 TRP n 
1 522 ILE n 
1 523 PRO n 
1 524 GLY n 
1 525 GLU n 
1 526 VAL n 
1 527 THR n 
1 528 PRO n 
1 529 ASP n 
1 530 PHE n 
1 531 GLU n 
1 532 THR n 
1 533 LYS n 
1 534 GLY n 
1 535 LEU n 
1 536 VAL n 
1 537 ASP n 
1 538 LEU n 
1 539 PRO n 
1 540 LYS n 
1 541 GLU n 
1 542 GLU n 
1 543 HIS n 
1 544 TRP n 
1 545 ALA n 
1 546 PRO n 
1 547 LEU n 
1 548 SER n 
1 549 GLN n 
1 550 SER n 
1 551 PRO n 
1 552 TYR n 
1 553 ASP n 
1 554 PRO n 
1 555 ASP n 
1 556 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   556 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PaG_05861 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Moesziomyces aphidis' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     84754 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?                                                                    'C3 H7 N O2'     
89.093  
ARG 'L-peptide linking' y ARGININE        ?                                                                    'C6 H15 N4 O2 1' 
175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?                                                                    'C4 H8 N2 O3'    
132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                                                                    'C4 H7 N O4'     
133.103 
CYS 'L-peptide linking' y CYSTEINE        ?                                                                    'C3 H7 N O2 S'   
121.158 
FE2 non-polymer         . 'FE (II) ION'   ?                                                                    'Fe 2'           
55.845  
GLN 'L-peptide linking' y GLUTAMINE       ?                                                                    'C5 H10 N2 O3'   
146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                                                                    'C5 H9 N O4'     
147.129 
GLY 'peptide linking'   y GLYCINE         ?                                                                    'C2 H5 N O2'     
75.067  
HIS 'L-peptide linking' y HISTIDINE       ?                                                                    'C6 H10 N3 O2 1' 
156.162 
HOH non-polymer         . WATER           ?                                                                    'H2 O'           
18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ?                                                                    'C6 H13 N O2'    
131.173 
LEU 'L-peptide linking' y LEUCINE         ?                                                                    'C6 H13 N O2'    
131.173 
LYS 'L-peptide linking' y LYSINE          ?                                                                    'C6 H15 N2 O2 1' 
147.195 
MET 'L-peptide linking' y METHIONINE      ?                                                                    'C5 H11 N O2 S'  
149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ?                                                                    'C9 H11 N O2'    
165.189 
PRO 'L-peptide linking' y PROLINE         ?                                                                    'C5 H9 N O2'     
115.130 
SER 'L-peptide linking' y SERINE          ?                                                                    'C3 H7 N O3'     
105.093 
THR 'L-peptide linking' y THREONINE       ?                                                                    'C4 H9 N O3'     
119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?                                                                    'C11 H12 N2 O2'  
204.225 
TYR 'L-peptide linking' y TYROSINE        ?                                                                    'C9 H11 N O3'    
181.189 
V9L non-polymer         . ortho-vanillin  '3-methoxy-2-oxidanyl-benzaldehyde; 2-hydroxy-3-methoxybenzaldehyde' 'C8 H8 O3'       
152.147 
VAL 'L-peptide linking' y VALINE          ?                                                                    'C5 H11 N O2'    
117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -7  ?   ?   ?   A . n 
A 1 2   TRP 2   -6  ?   ?   ?   A . n 
A 1 3   SER 3   -5  ?   ?   ?   A . n 
A 1 4   HIS 4   -4  ?   ?   ?   A . n 
A 1 5   PRO 5   -3  ?   ?   ?   A . n 
A 1 6   GLN 6   -2  ?   ?   ?   A . n 
A 1 7   PHE 7   -1  ?   ?   ?   A . n 
A 1 8   GLU 8   0   ?   ?   ?   A . n 
A 1 9   LYS 9   1   ?   ?   ?   A . n 
A 1 10  ALA 10  2   ?   ?   ?   A . n 
A 1 11  PRO 11  3   ?   ?   ?   A . n 
A 1 12  THR 12  4   ?   ?   ?   A . n 
A 1 13  ALA 13  5   ?   ?   ?   A . n 
A 1 14  THR 14  6   ?   ?   ?   A . n 
A 1 15  GLN 15  7   ?   ?   ?   A . n 
A 1 16  GLU 16  8   ?   ?   ?   A . n 
A 1 17  PRO 17  9   ?   ?   ?   A . n 
A 1 18  VAL 18  10  ?   ?   ?   A . n 
A 1 19  PRO 19  11  ?   ?   ?   A . n 
A 1 20  VAL 20  12  ?   ?   ?   A . n 
A 1 21  PRO 21  13  ?   ?   ?   A . n 
A 1 22  VAL 22  14  ?   ?   ?   A . n 
A 1 23  THR 23  15  ?   ?   ?   A . n 
A 1 24  SER 24  16  ?   ?   ?   A . n 
A 1 25  LYS 25  17  ?   ?   ?   A . n 
A 1 26  ALA 26  18  ?   ?   ?   A . n 
A 1 27  ALA 27  19  ?   ?   ?   A . n 
A 1 28  PRO 28  20  ?   ?   ?   A . n 
A 1 29  SER 29  21  ?   ?   ?   A . n 
A 1 30  HIS 30  22  ?   ?   ?   A . n 
A 1 31  GLY 31  23  ?   ?   ?   A . n 
A 1 32  TYR 32  24  32  TYR TYR A . n 
A 1 33  VAL 33  25  33  VAL VAL A . n 
A 1 34  HIS 34  26  34  HIS HIS A . n 
A 1 35  PRO 35  27  35  PRO PRO A . n 
A 1 36  THR 36  28  36  THR THR A . n 
A 1 37  ASP 37  29  37  ASP ASP A . n 
A 1 38  ILE 38  30  38  ILE ILE A . n 
A 1 39  LEU 39  31  39  LEU LEU A . n 
A 1 40  PRO 40  32  40  PRO PRO A . n 
A 1 41  SER 41  33  41  SER SER A . n 
A 1 42  GLY 42  34  42  GLY GLY A . n 
A 1 43  TRP 43  35  43  TRP TRP A . n 
A 1 44  PRO 44  36  44  PRO PRO A . n 
A 1 45  THR 45  37  45  THR THR A . n 
A 1 46  ALA 46  38  46  ALA ALA A . n 
A 1 47  THR 47  39  47  THR THR A . n 
A 1 48  ASP 48  40  48  ASP ASP A . n 
A 1 49  LEU 49  41  49  LEU LEU A . n 
A 1 50  SER 50  42  50  SER SER A . n 
A 1 51  GLY 51  43  51  GLY GLY A . n 
A 1 52  GLY 52  44  52  GLY GLY A . n 
A 1 53  ALA 53  45  53  ALA ALA A . n 
A 1 54  GLN 54  46  54  GLN GLN A . n 
A 1 55  PRO 55  47  55  PRO PRO A . n 
A 1 56  ARG 56  48  56  ARG ARG A . n 
A 1 57  ARG 57  49  57  ARG ARG A . n 
A 1 58  PHE 58  50  58  PHE PHE A . n 
A 1 59  GLU 59  51  59  GLU GLU A . n 
A 1 60  GLY 60  52  60  GLY GLY A . n 
A 1 61  THR 61  53  61  THR THR A . n 
A 1 62  ILE 62  54  62  ILE ILE A . n 
A 1 63  PHE 63  55  63  PHE PHE A . n 
A 1 64  ASP 64  56  64  ASP ASP A . n 
A 1 65  VAL 65  57  65  VAL VAL A . n 
A 1 66  MET 66  58  66  MET MET A . n 
A 1 67  THR 67  59  67  THR THR A . n 
A 1 68  ARG 68  60  68  ARG ARG A . n 
A 1 69  GLY 69  61  69  GLY GLY A . n 
A 1 70  THR 70  62  70  THR THR A . n 
A 1 71  ILE 71  63  71  ILE ILE A . n 
A 1 72  PRO 72  64  72  PRO PRO A . n 
A 1 73  LYS 73  65  73  LYS LYS A . n 
A 1 74  GLU 74  66  74  GLU GLU A . n 
A 1 75  LEU 75  67  75  LEU LEU A . n 
A 1 76  HIS 76  68  76  HIS HIS A . n 
A 1 77  GLY 77  69  77  GLY GLY A . n 
A 1 78  THR 78  70  78  THR THR A . n 
A 1 79  PHE 79  71  79  PHE PHE A . n 
A 1 80  TYR 80  72  80  TYR TYR A . n 
A 1 81  ARG 81  73  81  ARG ARG A . n 
A 1 82  ILE 82  74  82  ILE ILE A . n 
A 1 83  MET 83  75  83  MET MET A . n 
A 1 84  PRO 84  76  84  PRO PRO A . n 
A 1 85  ASP 85  77  85  ASP ASP A . n 
A 1 86  TYR 86  78  86  TYR TYR A . n 
A 1 87  ALA 87  79  87  ALA ALA A . n 
A 1 88  GLN 88  80  88  GLN GLN A . n 
A 1 89  PRO 89  81  89  PRO PRO A . n 
A 1 90  PRO 90  82  90  PRO PRO A . n 
A 1 91  THR 91  83  91  THR THR A . n 
A 1 92  TYR 92  84  92  TYR TYR A . n 
A 1 93  TYR 93  85  93  TYR TYR A . n 
A 1 94  LYS 94  86  94  LYS LYS A . n 
A 1 95  GLY 95  87  95  GLY GLY A . n 
A 1 96  GLY 96  88  96  GLY GLY A . n 
A 1 97  GLU 97  89  97  GLU GLU A . n 
A 1 98  LEU 98  90  98  LEU LEU A . n 
A 1 99  ASN 99  91  99  ASN ASN A . n 
A 1 100 ALA 100 92  100 ALA ALA A . n 
A 1 101 PRO 101 93  101 PRO PRO A . n 
A 1 102 ILE 102 94  102 ILE ILE A . n 
A 1 103 ASP 103 95  103 ASP ASP A . n 
A 1 104 GLY 104 96  104 GLY GLY A . n 
A 1 105 ASP 105 97  105 ASP ASP A . n 
A 1 106 GLY 106 98  106 GLY GLY A . n 
A 1 107 THR 107 99  107 THR THR A . n 
A 1 108 VAL 108 100 108 VAL VAL A . n 
A 1 109 ALA 109 101 109 ALA ALA A . n 
A 1 110 ALA 110 102 110 ALA ALA A . n 
A 1 111 PHE 111 103 111 PHE PHE A . n 
A 1 112 ARG 112 104 112 ARG ARG A . n 
A 1 113 PHE 113 105 113 PHE PHE A . n 
A 1 114 LYS 114 106 114 LYS LYS A . n 
A 1 115 ASP 115 107 115 ASP ASP A . n 
A 1 116 GLY 116 108 116 GLY GLY A . n 
A 1 117 LYS 117 109 117 LYS LYS A . n 
A 1 118 VAL 118 110 118 VAL VAL A . n 
A 1 119 ASP 119 111 119 ASP ASP A . n 
A 1 120 TYR 120 112 120 TYR TYR A . n 
A 1 121 ARG 121 113 121 ARG ARG A . n 
A 1 122 GLN 122 114 122 GLN GLN A . n 
A 1 123 ARG 123 115 123 ARG ARG A . n 
A 1 124 PHE 124 116 124 PHE PHE A . n 
A 1 125 VAL 125 117 125 VAL VAL A . n 
A 1 126 GLU 126 118 126 GLU GLU A . n 
A 1 127 THR 127 119 127 THR THR A . n 
A 1 128 ASP 128 120 128 ASP ASP A . n 
A 1 129 ARG 129 121 129 ARG ARG A . n 
A 1 130 PHE 130 122 130 PHE PHE A . n 
A 1 131 LYS 131 123 131 LYS LYS A . n 
A 1 132 VAL 132 124 132 VAL VAL A . n 
A 1 133 GLU 133 125 133 GLU GLU A . n 
A 1 134 ARG 134 126 134 ARG ARG A . n 
A 1 135 ARG 135 127 135 ARG ARG A . n 
A 1 136 ALA 136 128 136 ALA ALA A . n 
A 1 137 ARG 137 129 137 ARG ARG A . n 
A 1 138 LYS 138 130 138 LYS LYS A . n 
A 1 139 SER 139 131 139 SER SER A . n 
A 1 140 MET 140 132 140 MET MET A . n 
A 1 141 TYR 141 133 141 TYR TYR A . n 
A 1 142 GLY 142 134 142 GLY GLY A . n 
A 1 143 LEU 143 135 143 LEU LEU A . n 
A 1 144 TYR 144 136 144 TYR TYR A . n 
A 1 145 ARG 145 137 145 ARG ARG A . n 
A 1 146 ASN 146 138 146 ASN ASN A . n 
A 1 147 PRO 147 139 147 PRO PRO A . n 
A 1 148 TYR 148 140 148 TYR TYR A . n 
A 1 149 THR 149 141 149 THR THR A . n 
A 1 150 HIS 150 142 150 HIS HIS A . n 
A 1 151 HIS 151 143 151 HIS HIS A . n 
A 1 152 PRO 152 144 152 PRO PRO A . n 
A 1 153 CYS 153 145 153 CYS CYS A . n 
A 1 154 VAL 154 146 154 VAL VAL A . n 
A 1 155 ARG 155 147 155 ARG ARG A . n 
A 1 156 GLN 156 148 156 GLN GLN A . n 
A 1 157 THR 157 149 157 THR THR A . n 
A 1 158 VAL 158 150 158 VAL VAL A . n 
A 1 159 GLU 159 151 159 GLU GLU A . n 
A 1 160 SER 160 152 160 SER SER A . n 
A 1 161 THR 161 153 161 THR THR A . n 
A 1 162 ALA 162 154 162 ALA ALA A . n 
A 1 163 ASN 163 155 163 ASN ASN A . n 
A 1 164 THR 164 156 164 THR THR A . n 
A 1 165 ASN 165 157 165 ASN ASN A . n 
A 1 166 VAL 166 158 166 VAL VAL A . n 
A 1 167 VAL 167 159 167 VAL VAL A . n 
A 1 168 MET 168 160 168 MET MET A . n 
A 1 169 HIS 169 161 169 HIS HIS A . n 
A 1 170 ALA 170 162 170 ALA ALA A . n 
A 1 171 GLY 171 163 171 GLY GLY A . n 
A 1 172 ARG 172 164 172 ARG ARG A . n 
A 1 173 PHE 173 165 173 PHE PHE A . n 
A 1 174 LEU 174 166 174 LEU LEU A . n 
A 1 175 ALA 175 167 175 ALA ALA A . n 
A 1 176 MET 176 168 176 MET MET A . n 
A 1 177 LYS 177 169 177 LYS LYS A . n 
A 1 178 GLU 178 170 178 GLU GLU A . n 
A 1 179 ASN 179 171 179 ASN ASN A . n 
A 1 180 GLY 180 172 180 GLY GLY A . n 
A 1 181 ASN 181 173 181 ASN ASN A . n 
A 1 182 ALA 182 174 182 ALA ALA A . n 
A 1 183 TYR 183 175 183 TYR TYR A . n 
A 1 184 GLU 184 176 184 GLU GLU A . n 
A 1 185 MET 185 177 185 MET MET A . n 
A 1 186 ASP 186 178 186 ASP ASP A . n 
A 1 187 PRO 187 179 187 PRO PRO A . n 
A 1 188 HIS 188 180 188 HIS HIS A . n 
A 1 189 THR 189 181 189 THR THR A . n 
A 1 190 LEU 190 182 190 LEU LEU A . n 
A 1 191 LYS 191 183 191 LYS LYS A . n 
A 1 192 THR 192 184 192 THR THR A . n 
A 1 193 LEU 193 185 193 LEU LEU A . n 
A 1 194 GLY 194 186 194 GLY GLY A . n 
A 1 195 TYR 195 187 195 TYR TYR A . n 
A 1 196 ASN 196 188 196 ASN ASN A . n 
A 1 197 PRO 197 189 197 PRO PRO A . n 
A 1 198 PHE 198 190 198 PHE PHE A . n 
A 1 199 ASN 199 191 199 ASN ASN A . n 
A 1 200 LEU 200 192 200 LEU LEU A . n 
A 1 201 PRO 201 193 201 PRO PRO A . n 
A 1 202 SER 202 194 202 SER SER A . n 
A 1 203 LYS 203 195 203 LYS LYS A . n 
A 1 204 THR 204 196 204 THR THR A . n 
A 1 205 MET 205 197 205 MET MET A . n 
A 1 206 THR 206 198 206 THR THR A . n 
A 1 207 ALA 207 199 207 ALA ALA A . n 
A 1 208 HIS 208 200 208 HIS HIS A . n 
A 1 209 PRO 209 201 209 PRO PRO A . n 
A 1 210 LYS 210 202 210 LYS LYS A . n 
A 1 211 GLN 211 203 211 GLN GLN A . n 
A 1 212 CYS 212 204 212 CYS CYS A . n 
A 1 213 SER 213 205 213 SER SER A . n 
A 1 214 VAL 214 206 214 VAL VAL A . n 
A 1 215 THR 215 207 215 THR THR A . n 
A 1 216 GLY 216 208 216 GLY GLY A . n 
A 1 217 ASN 217 209 217 ASN ASN A . n 
A 1 218 LEU 218 210 218 LEU LEU A . n 
A 1 219 VAL 219 211 219 VAL VAL A . n 
A 1 220 GLY 220 212 220 GLY GLY A . n 
A 1 221 PHE 221 213 221 PHE PHE A . n 
A 1 222 GLY 222 214 222 GLY GLY A . n 
A 1 223 TYR 223 215 223 TYR TYR A . n 
A 1 224 GLU 224 216 224 GLU GLU A . n 
A 1 225 ALA 225 217 225 ALA ALA A . n 
A 1 226 LYS 226 218 226 LYS LYS A . n 
A 1 227 GLY 227 219 227 GLY GLY A . n 
A 1 228 LEU 228 220 228 LEU LEU A . n 
A 1 229 ALA 229 221 229 ALA ALA A . n 
A 1 230 THR 230 222 230 THR THR A . n 
A 1 231 LYS 231 223 231 LYS LYS A . n 
A 1 232 ASP 232 224 232 ASP ASP A . n 
A 1 233 VAL 233 225 233 VAL VAL A . n 
A 1 234 TYR 234 226 234 TYR TYR A . n 
A 1 235 TYR 235 227 235 TYR TYR A . n 
A 1 236 PHE 236 228 236 PHE PHE A . n 
A 1 237 GLU 237 229 237 GLU GLU A . n 
A 1 238 VAL 238 230 238 VAL VAL A . n 
A 1 239 ASP 239 231 239 ASP ASP A . n 
A 1 240 PRO 240 232 240 PRO PRO A . n 
A 1 241 SER 241 233 241 SER SER A . n 
A 1 242 GLY 242 234 242 GLY GLY A . n 
A 1 243 LYS 243 235 243 LYS LYS A . n 
A 1 244 VAL 244 236 244 VAL VAL A . n 
A 1 245 VAL 245 237 245 VAL VAL A . n 
A 1 246 ARG 246 238 246 ARG ARG A . n 
A 1 247 ASP 247 239 247 ASP ASP A . n 
A 1 248 LEU 248 240 248 LEU LEU A . n 
A 1 249 TRP 249 241 249 TRP TRP A . n 
A 1 250 LEU 250 242 250 LEU LEU A . n 
A 1 251 GLU 251 243 251 GLU GLU A . n 
A 1 252 ALA 252 244 252 ALA ALA A . n 
A 1 253 PRO 253 245 253 PRO PRO A . n 
A 1 254 TRP 254 246 254 TRP TRP A . n 
A 1 255 CYS 255 247 255 CYS CYS A . n 
A 1 256 ALA 256 248 256 ALA ALA A . n 
A 1 257 PHE 257 249 257 PHE PHE A . n 
A 1 258 ILE 258 250 258 ILE ILE A . n 
A 1 259 HIS 259 251 259 HIS HIS A . n 
A 1 260 ASP 260 252 260 ASP ASP A . n 
A 1 261 CYS 261 253 261 CYS CYS A . n 
A 1 262 ALA 262 254 262 ALA ALA A . n 
A 1 263 LEU 263 255 263 LEU LEU A . n 
A 1 264 THR 264 256 264 THR THR A . n 
A 1 265 PRO 265 257 265 PRO PRO A . n 
A 1 266 ASN 266 258 266 ASN ASN A . n 
A 1 267 TYR 267 259 267 TYR TYR A . n 
A 1 268 LEU 268 260 268 LEU LEU A . n 
A 1 269 VAL 269 261 269 VAL VAL A . n 
A 1 270 LEU 270 262 270 LEU LEU A . n 
A 1 271 MET 271 263 271 MET MET A . n 
A 1 272 LEU 272 264 272 LEU LEU A . n 
A 1 273 TRP 273 265 273 TRP TRP A . n 
A 1 274 PRO 274 266 274 PRO PRO A . n 
A 1 275 PHE 275 267 275 PHE PHE A . n 
A 1 276 GLU 276 268 276 GLU GLU A . n 
A 1 277 ALA 277 269 277 ALA ALA A . n 
A 1 278 ASN 278 270 278 ASN ASN A . n 
A 1 279 LEU 279 271 279 LEU LEU A . n 
A 1 280 GLU 280 272 280 GLU GLU A . n 
A 1 281 ARG 281 273 281 ARG ARG A . n 
A 1 282 MET 282 274 282 MET MET A . n 
A 1 283 LYS 283 275 283 LYS LYS A . n 
A 1 284 ALA 284 276 284 ALA ALA A . n 
A 1 285 GLY 285 277 285 GLY GLY A . n 
A 1 286 GLY 286 278 286 GLY GLY A . n 
A 1 287 HIS 287 279 287 HIS HIS A . n 
A 1 288 HIS 288 280 288 HIS HIS A . n 
A 1 289 TRP 289 281 289 TRP TRP A . n 
A 1 290 ALA 290 282 290 ALA ALA A . n 
A 1 291 TYR 291 283 291 TYR TYR A . n 
A 1 292 ASP 292 284 292 ASP ASP A . n 
A 1 293 TYR 293 285 293 TYR TYR A . n 
A 1 294 THR 294 286 294 THR THR A . n 
A 1 295 LYS 295 287 295 LYS LYS A . n 
A 1 296 PRO 296 288 296 PRO PRO A . n 
A 1 297 ILE 297 289 297 ILE ILE A . n 
A 1 298 THR 298 290 298 THR THR A . n 
A 1 299 TRP 299 291 299 TRP TRP A . n 
A 1 300 ILE 300 292 300 ILE ILE A . n 
A 1 301 THR 301 293 301 THR THR A . n 
A 1 302 ILE 302 294 302 ILE ILE A . n 
A 1 303 PRO 303 295 303 PRO PRO A . n 
A 1 304 ARG 304 296 304 ARG ARG A . n 
A 1 305 GLY 305 297 305 GLY GLY A . n 
A 1 306 ALA 306 298 306 ALA ALA A . n 
A 1 307 LYS 307 299 307 LYS LYS A . n 
A 1 308 SER 308 300 308 SER SER A . n 
A 1 309 LYS 309 301 309 LYS LYS A . n 
A 1 310 ASP 310 302 310 ASP ASP A . n 
A 1 311 GLU 311 303 311 GLU GLU A . n 
A 1 312 VAL 312 304 312 VAL VAL A . n 
A 1 313 LYS 313 305 313 LYS LYS A . n 
A 1 314 TYR 314 306 314 TYR TYR A . n 
A 1 315 TRP 315 307 315 TRP TRP A . n 
A 1 316 HIS 316 308 316 HIS HIS A . n 
A 1 317 TRP 317 309 317 TRP TRP A . n 
A 1 318 LYS 318 310 318 LYS LYS A . n 
A 1 319 ASN 319 311 319 ASN ASN A . n 
A 1 320 GLY 320 312 320 GLY GLY A . n 
A 1 321 MET 321 313 321 MET MET A . n 
A 1 322 PRO 322 314 322 PRO PRO A . n 
A 1 323 ILE 323 315 323 ILE ILE A . n 
A 1 324 HIS 324 316 324 HIS HIS A . n 
A 1 325 THR 325 317 325 THR THR A . n 
A 1 326 ALA 326 318 326 ALA ALA A . n 
A 1 327 SER 327 319 327 SER SER A . n 
A 1 328 GLY 328 320 328 GLY GLY A . n 
A 1 329 PHE 329 321 329 PHE PHE A . n 
A 1 330 GLU 330 322 330 GLU GLU A . n 
A 1 331 ASP 331 323 331 ASP ASP A . n 
A 1 332 GLU 332 324 332 GLU GLU A . n 
A 1 333 GLN 333 325 333 GLN GLN A . n 
A 1 334 GLY 334 326 334 GLY GLY A . n 
A 1 335 ARG 335 327 335 ARG ARG A . n 
A 1 336 ILE 336 328 336 ILE ILE A . n 
A 1 337 ILE 337 329 337 ILE ILE A . n 
A 1 338 ILE 338 330 338 ILE ILE A . n 
A 1 339 ASP 339 331 339 ASP ASP A . n 
A 1 340 SER 340 332 340 SER SER A . n 
A 1 341 SER 341 333 341 SER SER A . n 
A 1 342 LEU 342 334 342 LEU LEU A . n 
A 1 343 VAL 343 335 343 VAL VAL A . n 
A 1 344 HIS 344 336 344 HIS HIS A . n 
A 1 345 GLY 345 337 345 GLY GLY A . n 
A 1 346 ASN 346 338 346 ASN ASN A . n 
A 1 347 ALA 347 339 347 ALA ALA A . n 
A 1 348 PHE 348 340 348 PHE PHE A . n 
A 1 349 PRO 349 341 349 PRO PRO A . n 
A 1 350 PHE 350 342 350 PHE PHE A . n 
A 1 351 PHE 351 343 351 PHE PHE A . n 
A 1 352 PRO 352 344 352 PRO PRO A . n 
A 1 353 PRO 353 345 353 PRO PRO A . n 
A 1 354 ASP 354 346 354 ASP ASP A . n 
A 1 355 SER 355 347 355 SER SER A . n 
A 1 356 ASP 356 348 356 ASP ASP A . n 
A 1 357 GLU 357 349 357 GLU GLU A . n 
A 1 358 GLN 358 350 358 GLN GLN A . n 
A 1 359 LYS 359 351 359 LYS LYS A . n 
A 1 360 LYS 360 352 360 LYS LYS A . n 
A 1 361 LYS 361 353 361 LYS LYS A . n 
A 1 362 GLN 362 354 362 GLN GLN A . n 
A 1 363 GLU 363 355 363 GLU GLU A . n 
A 1 364 ALA 364 356 364 ALA ALA A . n 
A 1 365 ASP 365 357 365 ASP ASP A . n 
A 1 366 GLY 366 358 366 GLY GLY A . n 
A 1 367 THR 367 359 367 THR THR A . n 
A 1 368 PRO 368 360 368 PRO PRO A . n 
A 1 369 LYS 369 361 369 LYS LYS A . n 
A 1 370 ALA 370 362 370 ALA ALA A . n 
A 1 371 GLN 371 363 371 GLN GLN A . n 
A 1 372 PHE 372 364 372 PHE PHE A . n 
A 1 373 VAL 373 365 373 VAL VAL A . n 
A 1 374 ARG 374 366 374 ARG ARG A . n 
A 1 375 TRP 375 367 375 TRP TRP A . n 
A 1 376 THR 376 368 376 THR THR A . n 
A 1 377 ILE 377 369 377 ILE ILE A . n 
A 1 378 ASP 378 370 378 ASP ASP A . n 
A 1 379 PRO 379 371 379 PRO PRO A . n 
A 1 380 ARG 380 372 380 ARG ARG A . n 
A 1 381 LYS 381 373 381 LYS LYS A . n 
A 1 382 ASP 382 374 382 ASP ASP A . n 
A 1 383 ASN 383 375 383 ASN ASN A . n 
A 1 384 ASN 384 376 384 ASN ASN A . n 
A 1 385 GLU 385 377 385 GLU GLU A . n 
A 1 386 GLN 386 378 386 GLN GLN A . n 
A 1 387 LEU 387 379 387 LEU LEU A . n 
A 1 388 PRO 388 380 388 PRO PRO A . n 
A 1 389 ASP 389 381 389 ASP ASP A . n 
A 1 390 PRO 390 382 390 PRO PRO A . n 
A 1 391 GLU 391 383 391 GLU GLU A . n 
A 1 392 VAL 392 384 392 VAL VAL A . n 
A 1 393 ILE 393 385 393 ILE ILE A . n 
A 1 394 LEU 394 386 394 LEU LEU A . n 
A 1 395 ASP 395 387 395 ASP ASP A . n 
A 1 396 THR 396 388 396 THR THR A . n 
A 1 397 PRO 397 389 397 PRO PRO A . n 
A 1 398 SER 398 390 398 SER SER A . n 
A 1 399 GLU 399 391 399 GLU GLU A . n 
A 1 400 PHE 400 392 400 PHE PHE A . n 
A 1 401 PRO 401 393 401 PRO PRO A . n 
A 1 402 GLN 402 394 402 GLN GLN A . n 
A 1 403 ILE 403 395 403 ILE ILE A . n 
A 1 404 ASP 404 396 404 ASP ASP A . n 
A 1 405 ASN 405 397 405 ASN ASN A . n 
A 1 406 ARG 406 398 406 ARG ARG A . n 
A 1 407 PHE 407 399 407 PHE PHE A . n 
A 1 408 MET 408 400 408 MET MET A . n 
A 1 409 GLY 409 401 409 GLY GLY A . n 
A 1 410 VAL 410 402 410 VAL VAL A . n 
A 1 411 GLU 411 403 411 GLU GLU A . n 
A 1 412 TYR 412 404 412 TYR TYR A . n 
A 1 413 SER 413 405 413 SER SER A . n 
A 1 414 SER 414 406 414 SER SER A . n 
A 1 415 ALA 415 407 415 ALA ALA A . n 
A 1 416 PHE 416 408 416 PHE PHE A . n 
A 1 417 ILE 417 409 417 ILE ILE A . n 
A 1 418 ASN 418 410 418 ASN ASN A . n 
A 1 419 VAL 419 411 419 VAL VAL A . n 
A 1 420 PHE 420 412 420 PHE PHE A . n 
A 1 421 VAL 421 413 421 VAL VAL A . n 
A 1 422 PRO 422 414 422 PRO PRO A . n 
A 1 423 ASP 423 415 423 ASP ASP A . n 
A 1 424 ARG 424 416 424 ARG ARG A . n 
A 1 425 SER 425 417 425 SER SER A . n 
A 1 426 ASP 426 418 426 ASP ASP A . n 
A 1 427 GLY 427 419 427 GLY GLY A . n 
A 1 428 ASN 428 420 428 ASN ASN A . n 
A 1 429 LYS 429 421 429 LYS LYS A . n 
A 1 430 ASN 430 422 430 ASN ASN A . n 
A 1 431 VAL 431 423 431 VAL VAL A . n 
A 1 432 PHE 432 424 432 PHE PHE A . n 
A 1 433 GLN 433 425 433 GLN GLN A . n 
A 1 434 GLY 434 426 434 GLY GLY A . n 
A 1 435 LEU 435 427 435 LEU LEU A . n 
A 1 436 ASN 436 428 436 ASN ASN A . n 
A 1 437 GLY 437 429 437 GLY GLY A . n 
A 1 438 LEU 438 430 438 LEU LEU A . n 
A 1 439 ALA 439 431 439 ALA ALA A . n 
A 1 440 HIS 440 432 440 HIS HIS A . n 
A 1 441 TYR 441 433 441 TYR TYR A . n 
A 1 442 LYS 442 434 442 LYS LYS A . n 
A 1 443 ARG 443 435 443 ARG ARG A . n 
A 1 444 LYS 444 436 444 LYS LYS A . n 
A 1 445 GLU 445 437 445 GLU GLU A . n 
A 1 446 GLY 446 438 446 GLY GLY A . n 
A 1 447 THR 447 439 447 THR THR A . n 
A 1 448 THR 448 440 448 THR THR A . n 
A 1 449 GLU 449 441 449 GLU GLU A . n 
A 1 450 TRP 450 442 450 TRP TRP A . n 
A 1 451 TYR 451 443 451 TYR TYR A . n 
A 1 452 TYR 452 444 452 TYR TYR A . n 
A 1 453 ALA 453 445 453 ALA ALA A . n 
A 1 454 GLY 454 446 454 GLY GLY A . n 
A 1 455 ASP 455 447 455 ASP ASP A . n 
A 1 456 ASN 456 448 456 ASN ASN A . n 
A 1 457 CYS 457 449 457 CYS CYS A . n 
A 1 458 LEU 458 450 458 LEU LEU A . n 
A 1 459 ILE 459 451 459 ILE ILE A . n 
A 1 460 GLN 460 452 460 GLN GLN A . n 
A 1 461 GLU 461 453 461 GLU GLU A . n 
A 1 462 PRO 462 454 462 PRO PRO A . n 
A 1 463 VAL 463 455 463 VAL VAL A . n 
A 1 464 PHE 464 456 464 PHE PHE A . n 
A 1 465 SER 465 457 465 SER SER A . n 
A 1 466 PRO 466 458 466 PRO PRO A . n 
A 1 467 ARG 467 459 467 ARG ARG A . n 
A 1 468 SER 468 460 468 SER SER A . n 
A 1 469 LYS 469 461 469 LYS LYS A . n 
A 1 470 ASP 470 462 470 ASP ASP A . n 
A 1 471 ALA 471 463 471 ALA ALA A . n 
A 1 472 PRO 472 464 472 PRO PRO A . n 
A 1 473 GLU 473 465 473 GLU GLU A . n 
A 1 474 GLY 474 466 474 GLY GLY A . n 
A 1 475 ASP 475 467 475 ASP ASP A . n 
A 1 476 GLY 476 468 476 GLY GLY A . n 
A 1 477 PHE 477 469 477 PHE PHE A . n 
A 1 478 VAL 478 470 478 VAL VAL A . n 
A 1 479 LEU 479 471 479 LEU LEU A . n 
A 1 480 ALA 480 472 480 ALA ALA A . n 
A 1 481 ILE 481 473 481 ILE ILE A . n 
A 1 482 VAL 482 474 482 VAL VAL A . n 
A 1 483 ASP 483 475 483 ASP ASP A . n 
A 1 484 ARG 484 476 484 ARG ARG A . n 
A 1 485 LEU 485 477 485 LEU LEU A . n 
A 1 486 ASP 486 478 486 ASP ASP A . n 
A 1 487 LEU 487 479 487 LEU LEU A . n 
A 1 488 ASN 488 480 488 ASN ASN A . n 
A 1 489 ARG 489 481 489 ARG ARG A . n 
A 1 490 SER 490 482 490 SER SER A . n 
A 1 491 GLU 491 483 491 GLU GLU A . n 
A 1 492 VAL 492 484 492 VAL VAL A . n 
A 1 493 VAL 493 485 493 VAL VAL A . n 
A 1 494 VAL 494 486 494 VAL VAL A . n 
A 1 495 ILE 495 487 495 ILE ILE A . n 
A 1 496 ASP 496 488 496 ASP ASP A . n 
A 1 497 THR 497 489 497 THR THR A . n 
A 1 498 ARG 498 490 498 ARG ARG A . n 
A 1 499 ASP 499 491 499 ASP ASP A . n 
A 1 500 PHE 500 492 500 PHE PHE A . n 
A 1 501 THR 501 493 501 THR THR A . n 
A 1 502 LYS 502 494 502 LYS LYS A . n 
A 1 503 ALA 503 495 503 ALA ALA A . n 
A 1 504 VAL 504 496 504 VAL VAL A . n 
A 1 505 ALA 505 497 505 ALA ALA A . n 
A 1 506 ALA 506 498 506 ALA ALA A . n 
A 1 507 VAL 507 499 507 VAL VAL A . n 
A 1 508 GLN 508 500 508 GLN GLN A . n 
A 1 509 LEU 509 501 509 LEU LEU A . n 
A 1 510 PRO 510 502 510 PRO PRO A . n 
A 1 511 PHE 511 503 511 PHE PHE A . n 
A 1 512 ALA 512 504 512 ALA ALA A . n 
A 1 513 ILE 513 505 513 ILE ILE A . n 
A 1 514 ARG 514 506 514 ARG ARG A . n 
A 1 515 SER 515 507 515 SER SER A . n 
A 1 516 GLY 516 508 516 GLY GLY A . n 
A 1 517 ILE 517 509 517 ILE ILE A . n 
A 1 518 HIS 518 510 518 HIS HIS A . n 
A 1 519 GLY 519 511 519 GLY GLY A . n 
A 1 520 GLN 520 512 520 GLN GLN A . n 
A 1 521 TRP 521 513 521 TRP TRP A . n 
A 1 522 ILE 522 514 522 ILE ILE A . n 
A 1 523 PRO 523 515 523 PRO PRO A . n 
A 1 524 GLY 524 516 524 GLY GLY A . n 
A 1 525 GLU 525 517 525 GLU GLU A . n 
A 1 526 VAL 526 518 526 VAL VAL A . n 
A 1 527 THR 527 519 527 THR THR A . n 
A 1 528 PRO 528 520 528 PRO PRO A . n 
A 1 529 ASP 529 521 529 ASP ASP A . n 
A 1 530 PHE 530 522 530 PHE PHE A . n 
A 1 531 GLU 531 523 531 GLU GLU A . n 
A 1 532 THR 532 524 532 THR THR A . n 
A 1 533 LYS 533 525 533 LYS LYS A . n 
A 1 534 GLY 534 526 534 GLY GLY A . n 
A 1 535 LEU 535 527 535 LEU LEU A . n 
A 1 536 VAL 536 528 536 VAL VAL A . n 
A 1 537 ASP 537 529 537 ASP ASP A . n 
A 1 538 LEU 538 530 538 LEU LEU A . n 
A 1 539 PRO 539 531 539 PRO PRO A . n 
A 1 540 LYS 540 532 540 LYS LYS A . n 
A 1 541 GLU 541 533 541 GLU GLU A . n 
A 1 542 GLU 542 534 542 GLU GLU A . n 
A 1 543 HIS 543 535 543 HIS HIS A . n 
A 1 544 TRP 544 536 544 TRP TRP A . n 
A 1 545 ALA 545 537 545 ALA ALA A . n 
A 1 546 PRO 546 538 546 PRO PRO A . n 
A 1 547 LEU 547 539 547 LEU LEU A . n 
A 1 548 SER 548 540 548 SER SER A . n 
A 1 549 GLN 549 541 549 GLN GLN A . n 
A 1 550 SER 550 542 550 SER SER A . n 
A 1 551 PRO 551 543 551 PRO PRO A . n 
A 1 552 TYR 552 544 552 TYR TYR A . n 
A 1 553 ASP 553 545 553 ASP ASP A . n 
A 1 554 PRO 554 546 554 PRO PRO A . n 
A 1 555 ASP 555 547 555 ASP ASP A . n 
A 1 556 ALA 556 548 556 ALA ALA A . n 
B 1 1   MET 1   -7  ?   ?   ?   B . n 
B 1 2   TRP 2   -6  ?   ?   ?   B . n 
B 1 3   SER 3   -5  ?   ?   ?   B . n 
B 1 4   HIS 4   -4  ?   ?   ?   B . n 
B 1 5   PRO 5   -3  ?   ?   ?   B . n 
B 1 6   GLN 6   -2  ?   ?   ?   B . n 
B 1 7   PHE 7   -1  ?   ?   ?   B . n 
B 1 8   GLU 8   0   ?   ?   ?   B . n 
B 1 9   LYS 9   1   ?   ?   ?   B . n 
B 1 10  ALA 10  2   ?   ?   ?   B . n 
B 1 11  PRO 11  3   ?   ?   ?   B . n 
B 1 12  THR 12  4   ?   ?   ?   B . n 
B 1 13  ALA 13  5   ?   ?   ?   B . n 
B 1 14  THR 14  6   ?   ?   ?   B . n 
B 1 15  GLN 15  7   ?   ?   ?   B . n 
B 1 16  GLU 16  8   ?   ?   ?   B . n 
B 1 17  PRO 17  9   ?   ?   ?   B . n 
B 1 18  VAL 18  10  ?   ?   ?   B . n 
B 1 19  PRO 19  11  ?   ?   ?   B . n 
B 1 20  VAL 20  12  ?   ?   ?   B . n 
B 1 21  PRO 21  13  ?   ?   ?   B . n 
B 1 22  VAL 22  14  ?   ?   ?   B . n 
B 1 23  THR 23  15  ?   ?   ?   B . n 
B 1 24  SER 24  16  ?   ?   ?   B . n 
B 1 25  LYS 25  17  ?   ?   ?   B . n 
B 1 26  ALA 26  18  ?   ?   ?   B . n 
B 1 27  ALA 27  19  ?   ?   ?   B . n 
B 1 28  PRO 28  20  ?   ?   ?   B . n 
B 1 29  SER 29  21  ?   ?   ?   B . n 
B 1 30  HIS 30  22  ?   ?   ?   B . n 
B 1 31  GLY 31  23  ?   ?   ?   B . n 
B 1 32  TYR 32  24  32  TYR TYR B . n 
B 1 33  VAL 33  25  33  VAL VAL B . n 
B 1 34  HIS 34  26  34  HIS HIS B . n 
B 1 35  PRO 35  27  35  PRO PRO B . n 
B 1 36  THR 36  28  36  THR THR B . n 
B 1 37  ASP 37  29  37  ASP ASP B . n 
B 1 38  ILE 38  30  38  ILE ILE B . n 
B 1 39  LEU 39  31  39  LEU LEU B . n 
B 1 40  PRO 40  32  40  PRO PRO B . n 
B 1 41  SER 41  33  41  SER SER B . n 
B 1 42  GLY 42  34  42  GLY GLY B . n 
B 1 43  TRP 43  35  43  TRP TRP B . n 
B 1 44  PRO 44  36  44  PRO PRO B . n 
B 1 45  THR 45  37  45  THR THR B . n 
B 1 46  ALA 46  38  46  ALA ALA B . n 
B 1 47  THR 47  39  47  THR THR B . n 
B 1 48  ASP 48  40  48  ASP ASP B . n 
B 1 49  LEU 49  41  49  LEU LEU B . n 
B 1 50  SER 50  42  50  SER SER B . n 
B 1 51  GLY 51  43  51  GLY GLY B . n 
B 1 52  GLY 52  44  52  GLY GLY B . n 
B 1 53  ALA 53  45  53  ALA ALA B . n 
B 1 54  GLN 54  46  54  GLN GLN B . n 
B 1 55  PRO 55  47  55  PRO PRO B . n 
B 1 56  ARG 56  48  56  ARG ARG B . n 
B 1 57  ARG 57  49  57  ARG ARG B . n 
B 1 58  PHE 58  50  58  PHE PHE B . n 
B 1 59  GLU 59  51  59  GLU GLU B . n 
B 1 60  GLY 60  52  60  GLY GLY B . n 
B 1 61  THR 61  53  61  THR THR B . n 
B 1 62  ILE 62  54  62  ILE ILE B . n 
B 1 63  PHE 63  55  63  PHE PHE B . n 
B 1 64  ASP 64  56  64  ASP ASP B . n 
B 1 65  VAL 65  57  65  VAL VAL B . n 
B 1 66  MET 66  58  66  MET MET B . n 
B 1 67  THR 67  59  67  THR THR B . n 
B 1 68  ARG 68  60  68  ARG ARG B . n 
B 1 69  GLY 69  61  69  GLY GLY B . n 
B 1 70  THR 70  62  70  THR THR B . n 
B 1 71  ILE 71  63  71  ILE ILE B . n 
B 1 72  PRO 72  64  72  PRO PRO B . n 
B 1 73  LYS 73  65  73  LYS LYS B . n 
B 1 74  GLU 74  66  74  GLU GLU B . n 
B 1 75  LEU 75  67  75  LEU LEU B . n 
B 1 76  HIS 76  68  76  HIS HIS B . n 
B 1 77  GLY 77  69  77  GLY GLY B . n 
B 1 78  THR 78  70  78  THR THR B . n 
B 1 79  PHE 79  71  79  PHE PHE B . n 
B 1 80  TYR 80  72  80  TYR TYR B . n 
B 1 81  ARG 81  73  81  ARG ARG B . n 
B 1 82  ILE 82  74  82  ILE ILE B . n 
B 1 83  MET 83  75  83  MET MET B . n 
B 1 84  PRO 84  76  84  PRO PRO B . n 
B 1 85  ASP 85  77  85  ASP ASP B . n 
B 1 86  TYR 86  78  86  TYR TYR B . n 
B 1 87  ALA 87  79  87  ALA ALA B . n 
B 1 88  GLN 88  80  88  GLN GLN B . n 
B 1 89  PRO 89  81  89  PRO PRO B . n 
B 1 90  PRO 90  82  90  PRO PRO B . n 
B 1 91  THR 91  83  91  THR THR B . n 
B 1 92  TYR 92  84  92  TYR TYR B . n 
B 1 93  TYR 93  85  93  TYR TYR B . n 
B 1 94  LYS 94  86  94  LYS LYS B . n 
B 1 95  GLY 95  87  95  GLY GLY B . n 
B 1 96  GLY 96  88  96  GLY GLY B . n 
B 1 97  GLU 97  89  97  GLU GLU B . n 
B 1 98  LEU 98  90  98  LEU LEU B . n 
B 1 99  ASN 99  91  99  ASN ASN B . n 
B 1 100 ALA 100 92  100 ALA ALA B . n 
B 1 101 PRO 101 93  101 PRO PRO B . n 
B 1 102 ILE 102 94  102 ILE ILE B . n 
B 1 103 ASP 103 95  103 ASP ASP B . n 
B 1 104 GLY 104 96  104 GLY GLY B . n 
B 1 105 ASP 105 97  105 ASP ASP B . n 
B 1 106 GLY 106 98  106 GLY GLY B . n 
B 1 107 THR 107 99  107 THR THR B . n 
B 1 108 VAL 108 100 108 VAL VAL B . n 
B 1 109 ALA 109 101 109 ALA ALA B . n 
B 1 110 ALA 110 102 110 ALA ALA B . n 
B 1 111 PHE 111 103 111 PHE PHE B . n 
B 1 112 ARG 112 104 112 ARG ARG B . n 
B 1 113 PHE 113 105 113 PHE PHE B . n 
B 1 114 LYS 114 106 114 LYS LYS B . n 
B 1 115 ASP 115 107 115 ASP ASP B . n 
B 1 116 GLY 116 108 116 GLY GLY B . n 
B 1 117 LYS 117 109 117 LYS LYS B . n 
B 1 118 VAL 118 110 118 VAL VAL B . n 
B 1 119 ASP 119 111 119 ASP ASP B . n 
B 1 120 TYR 120 112 120 TYR TYR B . n 
B 1 121 ARG 121 113 121 ARG ARG B . n 
B 1 122 GLN 122 114 122 GLN GLN B . n 
B 1 123 ARG 123 115 123 ARG ARG B . n 
B 1 124 PHE 124 116 124 PHE PHE B . n 
B 1 125 VAL 125 117 125 VAL VAL B . n 
B 1 126 GLU 126 118 126 GLU GLU B . n 
B 1 127 THR 127 119 127 THR THR B . n 
B 1 128 ASP 128 120 128 ASP ASP B . n 
B 1 129 ARG 129 121 129 ARG ARG B . n 
B 1 130 PHE 130 122 130 PHE PHE B . n 
B 1 131 LYS 131 123 131 LYS LYS B . n 
B 1 132 VAL 132 124 132 VAL VAL B . n 
B 1 133 GLU 133 125 133 GLU GLU B . n 
B 1 134 ARG 134 126 134 ARG ARG B . n 
B 1 135 ARG 135 127 135 ARG ARG B . n 
B 1 136 ALA 136 128 136 ALA ALA B . n 
B 1 137 ARG 137 129 137 ARG ARG B . n 
B 1 138 LYS 138 130 138 LYS LYS B . n 
B 1 139 SER 139 131 139 SER SER B . n 
B 1 140 MET 140 132 140 MET MET B . n 
B 1 141 TYR 141 133 141 TYR TYR B . n 
B 1 142 GLY 142 134 142 GLY GLY B . n 
B 1 143 LEU 143 135 143 LEU LEU B . n 
B 1 144 TYR 144 136 144 TYR TYR B . n 
B 1 145 ARG 145 137 145 ARG ARG B . n 
B 1 146 ASN 146 138 146 ASN ASN B . n 
B 1 147 PRO 147 139 147 PRO PRO B . n 
B 1 148 TYR 148 140 148 TYR TYR B . n 
B 1 149 THR 149 141 149 THR THR B . n 
B 1 150 HIS 150 142 150 HIS HIS B . n 
B 1 151 HIS 151 143 151 HIS HIS B . n 
B 1 152 PRO 152 144 152 PRO PRO B . n 
B 1 153 CYS 153 145 153 CYS CYS B . n 
B 1 154 VAL 154 146 154 VAL VAL B . n 
B 1 155 ARG 155 147 155 ARG ARG B . n 
B 1 156 GLN 156 148 156 GLN GLN B . n 
B 1 157 THR 157 149 157 THR THR B . n 
B 1 158 VAL 158 150 158 VAL VAL B . n 
B 1 159 GLU 159 151 159 GLU GLU B . n 
B 1 160 SER 160 152 160 SER SER B . n 
B 1 161 THR 161 153 161 THR THR B . n 
B 1 162 ALA 162 154 162 ALA ALA B . n 
B 1 163 ASN 163 155 163 ASN ASN B . n 
B 1 164 THR 164 156 164 THR THR B . n 
B 1 165 ASN 165 157 165 ASN ASN B . n 
B 1 166 VAL 166 158 166 VAL VAL B . n 
B 1 167 VAL 167 159 167 VAL VAL B . n 
B 1 168 MET 168 160 168 MET MET B . n 
B 1 169 HIS 169 161 169 HIS HIS B . n 
B 1 170 ALA 170 162 170 ALA ALA B . n 
B 1 171 GLY 171 163 171 GLY GLY B . n 
B 1 172 ARG 172 164 172 ARG ARG B . n 
B 1 173 PHE 173 165 173 PHE PHE B . n 
B 1 174 LEU 174 166 174 LEU LEU B . n 
B 1 175 ALA 175 167 175 ALA ALA B . n 
B 1 176 MET 176 168 176 MET MET B . n 
B 1 177 LYS 177 169 177 LYS LYS B . n 
B 1 178 GLU 178 170 178 GLU GLU B . n 
B 1 179 ASN 179 171 179 ASN ASN B . n 
B 1 180 GLY 180 172 180 GLY GLY B . n 
B 1 181 ASN 181 173 181 ASN ASN B . n 
B 1 182 ALA 182 174 182 ALA ALA B . n 
B 1 183 TYR 183 175 183 TYR TYR B . n 
B 1 184 GLU 184 176 184 GLU GLU B . n 
B 1 185 MET 185 177 185 MET MET B . n 
B 1 186 ASP 186 178 186 ASP ASP B . n 
B 1 187 PRO 187 179 187 PRO PRO B . n 
B 1 188 HIS 188 180 188 HIS HIS B . n 
B 1 189 THR 189 181 189 THR THR B . n 
B 1 190 LEU 190 182 190 LEU LEU B . n 
B 1 191 LYS 191 183 191 LYS LYS B . n 
B 1 192 THR 192 184 192 THR THR B . n 
B 1 193 LEU 193 185 193 LEU LEU B . n 
B 1 194 GLY 194 186 194 GLY GLY B . n 
B 1 195 TYR 195 187 195 TYR TYR B . n 
B 1 196 ASN 196 188 196 ASN ASN B . n 
B 1 197 PRO 197 189 197 PRO PRO B . n 
B 1 198 PHE 198 190 198 PHE PHE B . n 
B 1 199 ASN 199 191 199 ASN ASN B . n 
B 1 200 LEU 200 192 200 LEU LEU B . n 
B 1 201 PRO 201 193 201 PRO PRO B . n 
B 1 202 SER 202 194 202 SER SER B . n 
B 1 203 LYS 203 195 203 LYS LYS B . n 
B 1 204 THR 204 196 204 THR THR B . n 
B 1 205 MET 205 197 205 MET MET B . n 
B 1 206 THR 206 198 206 THR THR B . n 
B 1 207 ALA 207 199 207 ALA ALA B . n 
B 1 208 HIS 208 200 208 HIS HIS B . n 
B 1 209 PRO 209 201 209 PRO PRO B . n 
B 1 210 LYS 210 202 210 LYS LYS B . n 
B 1 211 GLN 211 203 211 GLN GLN B . n 
B 1 212 CYS 212 204 212 CYS CYS B . n 
B 1 213 SER 213 205 213 SER SER B . n 
B 1 214 VAL 214 206 214 VAL VAL B . n 
B 1 215 THR 215 207 215 THR THR B . n 
B 1 216 GLY 216 208 216 GLY GLY B . n 
B 1 217 ASN 217 209 217 ASN ASN B . n 
B 1 218 LEU 218 210 218 LEU LEU B . n 
B 1 219 VAL 219 211 219 VAL VAL B . n 
B 1 220 GLY 220 212 220 GLY GLY B . n 
B 1 221 PHE 221 213 221 PHE PHE B . n 
B 1 222 GLY 222 214 222 GLY GLY B . n 
B 1 223 TYR 223 215 223 TYR TYR B . n 
B 1 224 GLU 224 216 224 GLU GLU B . n 
B 1 225 ALA 225 217 225 ALA ALA B . n 
B 1 226 LYS 226 218 226 LYS LYS B . n 
B 1 227 GLY 227 219 227 GLY GLY B . n 
B 1 228 LEU 228 220 228 LEU LEU B . n 
B 1 229 ALA 229 221 229 ALA ALA B . n 
B 1 230 THR 230 222 230 THR THR B . n 
B 1 231 LYS 231 223 231 LYS LYS B . n 
B 1 232 ASP 232 224 232 ASP ASP B . n 
B 1 233 VAL 233 225 233 VAL VAL B . n 
B 1 234 TYR 234 226 234 TYR TYR B . n 
B 1 235 TYR 235 227 235 TYR TYR B . n 
B 1 236 PHE 236 228 236 PHE PHE B . n 
B 1 237 GLU 237 229 237 GLU GLU B . n 
B 1 238 VAL 238 230 238 VAL VAL B . n 
B 1 239 ASP 239 231 239 ASP ASP B . n 
B 1 240 PRO 240 232 240 PRO PRO B . n 
B 1 241 SER 241 233 241 SER SER B . n 
B 1 242 GLY 242 234 242 GLY GLY B . n 
B 1 243 LYS 243 235 243 LYS LYS B . n 
B 1 244 VAL 244 236 244 VAL VAL B . n 
B 1 245 VAL 245 237 245 VAL VAL B . n 
B 1 246 ARG 246 238 246 ARG ARG B . n 
B 1 247 ASP 247 239 247 ASP ASP B . n 
B 1 248 LEU 248 240 248 LEU LEU B . n 
B 1 249 TRP 249 241 249 TRP TRP B . n 
B 1 250 LEU 250 242 250 LEU LEU B . n 
B 1 251 GLU 251 243 251 GLU GLU B . n 
B 1 252 ALA 252 244 252 ALA ALA B . n 
B 1 253 PRO 253 245 253 PRO PRO B . n 
B 1 254 TRP 254 246 254 TRP TRP B . n 
B 1 255 CYS 255 247 255 CYS CYS B . n 
B 1 256 ALA 256 248 256 ALA ALA B . n 
B 1 257 PHE 257 249 257 PHE PHE B . n 
B 1 258 ILE 258 250 258 ILE ILE B . n 
B 1 259 HIS 259 251 259 HIS HIS B . n 
B 1 260 ASP 260 252 260 ASP ASP B . n 
B 1 261 CYS 261 253 261 CYS CYS B . n 
B 1 262 ALA 262 254 262 ALA ALA B . n 
B 1 263 LEU 263 255 263 LEU LEU B . n 
B 1 264 THR 264 256 264 THR THR B . n 
B 1 265 PRO 265 257 265 PRO PRO B . n 
B 1 266 ASN 266 258 266 ASN ASN B . n 
B 1 267 TYR 267 259 267 TYR TYR B . n 
B 1 268 LEU 268 260 268 LEU LEU B . n 
B 1 269 VAL 269 261 269 VAL VAL B . n 
B 1 270 LEU 270 262 270 LEU LEU B . n 
B 1 271 MET 271 263 271 MET MET B . n 
B 1 272 LEU 272 264 272 LEU LEU B . n 
B 1 273 TRP 273 265 273 TRP TRP B . n 
B 1 274 PRO 274 266 274 PRO PRO B . n 
B 1 275 PHE 275 267 275 PHE PHE B . n 
B 1 276 GLU 276 268 276 GLU GLU B . n 
B 1 277 ALA 277 269 277 ALA ALA B . n 
B 1 278 ASN 278 270 278 ASN ASN B . n 
B 1 279 LEU 279 271 279 LEU LEU B . n 
B 1 280 GLU 280 272 280 GLU GLU B . n 
B 1 281 ARG 281 273 281 ARG ARG B . n 
B 1 282 MET 282 274 282 MET MET B . n 
B 1 283 LYS 283 275 283 LYS LYS B . n 
B 1 284 ALA 284 276 284 ALA ALA B . n 
B 1 285 GLY 285 277 285 GLY GLY B . n 
B 1 286 GLY 286 278 286 GLY GLY B . n 
B 1 287 HIS 287 279 287 HIS HIS B . n 
B 1 288 HIS 288 280 288 HIS HIS B . n 
B 1 289 TRP 289 281 289 TRP TRP B . n 
B 1 290 ALA 290 282 290 ALA ALA B . n 
B 1 291 TYR 291 283 291 TYR TYR B . n 
B 1 292 ASP 292 284 292 ASP ASP B . n 
B 1 293 TYR 293 285 293 TYR TYR B . n 
B 1 294 THR 294 286 294 THR THR B . n 
B 1 295 LYS 295 287 295 LYS LYS B . n 
B 1 296 PRO 296 288 296 PRO PRO B . n 
B 1 297 ILE 297 289 297 ILE ILE B . n 
B 1 298 THR 298 290 298 THR THR B . n 
B 1 299 TRP 299 291 299 TRP TRP B . n 
B 1 300 ILE 300 292 300 ILE ILE B . n 
B 1 301 THR 301 293 301 THR THR B . n 
B 1 302 ILE 302 294 302 ILE ILE B . n 
B 1 303 PRO 303 295 303 PRO PRO B . n 
B 1 304 ARG 304 296 304 ARG ARG B . n 
B 1 305 GLY 305 297 305 GLY GLY B . n 
B 1 306 ALA 306 298 306 ALA ALA B . n 
B 1 307 LYS 307 299 307 LYS LYS B . n 
B 1 308 SER 308 300 308 SER SER B . n 
B 1 309 LYS 309 301 309 LYS LYS B . n 
B 1 310 ASP 310 302 310 ASP ASP B . n 
B 1 311 GLU 311 303 311 GLU GLU B . n 
B 1 312 VAL 312 304 312 VAL VAL B . n 
B 1 313 LYS 313 305 313 LYS LYS B . n 
B 1 314 TYR 314 306 314 TYR TYR B . n 
B 1 315 TRP 315 307 315 TRP TRP B . n 
B 1 316 HIS 316 308 316 HIS HIS B . n 
B 1 317 TRP 317 309 317 TRP TRP B . n 
B 1 318 LYS 318 310 318 LYS LYS B . n 
B 1 319 ASN 319 311 319 ASN ASN B . n 
B 1 320 GLY 320 312 320 GLY GLY B . n 
B 1 321 MET 321 313 321 MET MET B . n 
B 1 322 PRO 322 314 322 PRO PRO B . n 
B 1 323 ILE 323 315 323 ILE ILE B . n 
B 1 324 HIS 324 316 324 HIS HIS B . n 
B 1 325 THR 325 317 325 THR THR B . n 
B 1 326 ALA 326 318 326 ALA ALA B . n 
B 1 327 SER 327 319 327 SER SER B . n 
B 1 328 GLY 328 320 328 GLY GLY B . n 
B 1 329 PHE 329 321 329 PHE PHE B . n 
B 1 330 GLU 330 322 330 GLU GLU B . n 
B 1 331 ASP 331 323 331 ASP ASP B . n 
B 1 332 GLU 332 324 332 GLU GLU B . n 
B 1 333 GLN 333 325 333 GLN GLN B . n 
B 1 334 GLY 334 326 334 GLY GLY B . n 
B 1 335 ARG 335 327 335 ARG ARG B . n 
B 1 336 ILE 336 328 336 ILE ILE B . n 
B 1 337 ILE 337 329 337 ILE ILE B . n 
B 1 338 ILE 338 330 338 ILE ILE B . n 
B 1 339 ASP 339 331 339 ASP ASP B . n 
B 1 340 SER 340 332 340 SER SER B . n 
B 1 341 SER 341 333 341 SER SER B . n 
B 1 342 LEU 342 334 342 LEU LEU B . n 
B 1 343 VAL 343 335 343 VAL VAL B . n 
B 1 344 HIS 344 336 344 HIS HIS B . n 
B 1 345 GLY 345 337 345 GLY GLY B . n 
B 1 346 ASN 346 338 346 ASN ASN B . n 
B 1 347 ALA 347 339 347 ALA ALA B . n 
B 1 348 PHE 348 340 348 PHE PHE B . n 
B 1 349 PRO 349 341 349 PRO PRO B . n 
B 1 350 PHE 350 342 350 PHE PHE B . n 
B 1 351 PHE 351 343 351 PHE PHE B . n 
B 1 352 PRO 352 344 352 PRO PRO B . n 
B 1 353 PRO 353 345 353 PRO PRO B . n 
B 1 354 ASP 354 346 354 ASP ASP B . n 
B 1 355 SER 355 347 355 SER SER B . n 
B 1 356 ASP 356 348 356 ASP ASP B . n 
B 1 357 GLU 357 349 357 GLU GLU B . n 
B 1 358 GLN 358 350 358 GLN GLN B . n 
B 1 359 LYS 359 351 359 LYS LYS B . n 
B 1 360 LYS 360 352 360 LYS LYS B . n 
B 1 361 LYS 361 353 361 LYS LYS B . n 
B 1 362 GLN 362 354 362 GLN GLN B . n 
B 1 363 GLU 363 355 363 GLU GLU B . n 
B 1 364 ALA 364 356 364 ALA ALA B . n 
B 1 365 ASP 365 357 365 ASP ASP B . n 
B 1 366 GLY 366 358 366 GLY GLY B . n 
B 1 367 THR 367 359 367 THR THR B . n 
B 1 368 PRO 368 360 368 PRO PRO B . n 
B 1 369 LYS 369 361 369 LYS LYS B . n 
B 1 370 ALA 370 362 370 ALA ALA B . n 
B 1 371 GLN 371 363 371 GLN GLN B . n 
B 1 372 PHE 372 364 372 PHE PHE B . n 
B 1 373 VAL 373 365 373 VAL VAL B . n 
B 1 374 ARG 374 366 374 ARG ARG B . n 
B 1 375 TRP 375 367 375 TRP TRP B . n 
B 1 376 THR 376 368 376 THR THR B . n 
B 1 377 ILE 377 369 377 ILE ILE B . n 
B 1 378 ASP 378 370 378 ASP ASP B . n 
B 1 379 PRO 379 371 379 PRO PRO B . n 
B 1 380 ARG 380 372 380 ARG ARG B . n 
B 1 381 LYS 381 373 381 LYS LYS B . n 
B 1 382 ASP 382 374 382 ASP ASP B . n 
B 1 383 ASN 383 375 383 ASN ASN B . n 
B 1 384 ASN 384 376 384 ASN ASN B . n 
B 1 385 GLU 385 377 385 GLU GLU B . n 
B 1 386 GLN 386 378 386 GLN GLN B . n 
B 1 387 LEU 387 379 387 LEU LEU B . n 
B 1 388 PRO 388 380 388 PRO PRO B . n 
B 1 389 ASP 389 381 389 ASP ASP B . n 
B 1 390 PRO 390 382 390 PRO PRO B . n 
B 1 391 GLU 391 383 391 GLU GLU B . n 
B 1 392 VAL 392 384 392 VAL VAL B . n 
B 1 393 ILE 393 385 393 ILE ILE B . n 
B 1 394 LEU 394 386 394 LEU LEU B . n 
B 1 395 ASP 395 387 395 ASP ASP B . n 
B 1 396 THR 396 388 396 THR THR B . n 
B 1 397 PRO 397 389 397 PRO PRO B . n 
B 1 398 SER 398 390 398 SER SER B . n 
B 1 399 GLU 399 391 399 GLU GLU B . n 
B 1 400 PHE 400 392 400 PHE PHE B . n 
B 1 401 PRO 401 393 401 PRO PRO B . n 
B 1 402 GLN 402 394 402 GLN GLN B . n 
B 1 403 ILE 403 395 403 ILE ILE B . n 
B 1 404 ASP 404 396 404 ASP ASP B . n 
B 1 405 ASN 405 397 405 ASN ASN B . n 
B 1 406 ARG 406 398 406 ARG ARG B . n 
B 1 407 PHE 407 399 407 PHE PHE B . n 
B 1 408 MET 408 400 408 MET MET B . n 
B 1 409 GLY 409 401 409 GLY GLY B . n 
B 1 410 VAL 410 402 410 VAL VAL B . n 
B 1 411 GLU 411 403 411 GLU GLU B . n 
B 1 412 TYR 412 404 412 TYR TYR B . n 
B 1 413 SER 413 405 413 SER SER B . n 
B 1 414 SER 414 406 414 SER SER B . n 
B 1 415 ALA 415 407 415 ALA ALA B . n 
B 1 416 PHE 416 408 416 PHE PHE B . n 
B 1 417 ILE 417 409 417 ILE ILE B . n 
B 1 418 ASN 418 410 418 ASN ASN B . n 
B 1 419 VAL 419 411 419 VAL VAL B . n 
B 1 420 PHE 420 412 420 PHE PHE B . n 
B 1 421 VAL 421 413 421 VAL VAL B . n 
B 1 422 PRO 422 414 422 PRO PRO B . n 
B 1 423 ASP 423 415 423 ASP ASP B . n 
B 1 424 ARG 424 416 424 ARG ARG B . n 
B 1 425 SER 425 417 425 SER SER B . n 
B 1 426 ASP 426 418 426 ASP ASP B . n 
B 1 427 GLY 427 419 427 GLY GLY B . n 
B 1 428 ASN 428 420 428 ASN ASN B . n 
B 1 429 LYS 429 421 429 LYS LYS B . n 
B 1 430 ASN 430 422 430 ASN ASN B . n 
B 1 431 VAL 431 423 431 VAL VAL B . n 
B 1 432 PHE 432 424 432 PHE PHE B . n 
B 1 433 GLN 433 425 433 GLN GLN B . n 
B 1 434 GLY 434 426 434 GLY GLY B . n 
B 1 435 LEU 435 427 435 LEU LEU B . n 
B 1 436 ASN 436 428 436 ASN ASN B . n 
B 1 437 GLY 437 429 437 GLY GLY B . n 
B 1 438 LEU 438 430 438 LEU LEU B . n 
B 1 439 ALA 439 431 439 ALA ALA B . n 
B 1 440 HIS 440 432 440 HIS HIS B . n 
B 1 441 TYR 441 433 441 TYR TYR B . n 
B 1 442 LYS 442 434 442 LYS LYS B . n 
B 1 443 ARG 443 435 443 ARG ARG B . n 
B 1 444 LYS 444 436 444 LYS LYS B . n 
B 1 445 GLU 445 437 445 GLU GLU B . n 
B 1 446 GLY 446 438 446 GLY GLY B . n 
B 1 447 THR 447 439 447 THR THR B . n 
B 1 448 THR 448 440 448 THR THR B . n 
B 1 449 GLU 449 441 449 GLU GLU B . n 
B 1 450 TRP 450 442 450 TRP TRP B . n 
B 1 451 TYR 451 443 451 TYR TYR B . n 
B 1 452 TYR 452 444 452 TYR TYR B . n 
B 1 453 ALA 453 445 453 ALA ALA B . n 
B 1 454 GLY 454 446 454 GLY GLY B . n 
B 1 455 ASP 455 447 455 ASP ASP B . n 
B 1 456 ASN 456 448 456 ASN ASN B . n 
B 1 457 CYS 457 449 457 CYS CYS B . n 
B 1 458 LEU 458 450 458 LEU LEU B . n 
B 1 459 ILE 459 451 459 ILE ILE B . n 
B 1 460 GLN 460 452 460 GLN GLN B . n 
B 1 461 GLU 461 453 461 GLU GLU B . n 
B 1 462 PRO 462 454 462 PRO PRO B . n 
B 1 463 VAL 463 455 463 VAL VAL B . n 
B 1 464 PHE 464 456 464 PHE PHE B . n 
B 1 465 SER 465 457 465 SER SER B . n 
B 1 466 PRO 466 458 466 PRO PRO B . n 
B 1 467 ARG 467 459 467 ARG ARG B . n 
B 1 468 SER 468 460 468 SER SER B . n 
B 1 469 LYS 469 461 469 LYS LYS B . n 
B 1 470 ASP 470 462 470 ASP ASP B . n 
B 1 471 ALA 471 463 471 ALA ALA B . n 
B 1 472 PRO 472 464 472 PRO PRO B . n 
B 1 473 GLU 473 465 473 GLU GLU B . n 
B 1 474 GLY 474 466 474 GLY GLY B . n 
B 1 475 ASP 475 467 475 ASP ASP B . n 
B 1 476 GLY 476 468 476 GLY GLY B . n 
B 1 477 PHE 477 469 477 PHE PHE B . n 
B 1 478 VAL 478 470 478 VAL VAL B . n 
B 1 479 LEU 479 471 479 LEU LEU B . n 
B 1 480 ALA 480 472 480 ALA ALA B . n 
B 1 481 ILE 481 473 481 ILE ILE B . n 
B 1 482 VAL 482 474 482 VAL VAL B . n 
B 1 483 ASP 483 475 483 ASP ASP B . n 
B 1 484 ARG 484 476 484 ARG ARG B . n 
B 1 485 LEU 485 477 485 LEU LEU B . n 
B 1 486 ASP 486 478 486 ASP ASP B . n 
B 1 487 LEU 487 479 487 LEU LEU B . n 
B 1 488 ASN 488 480 488 ASN ASN B . n 
B 1 489 ARG 489 481 489 ARG ARG B . n 
B 1 490 SER 490 482 490 SER SER B . n 
B 1 491 GLU 491 483 491 GLU GLU B . n 
B 1 492 VAL 492 484 492 VAL VAL B . n 
B 1 493 VAL 493 485 493 VAL VAL B . n 
B 1 494 VAL 494 486 494 VAL VAL B . n 
B 1 495 ILE 495 487 495 ILE ILE B . n 
B 1 496 ASP 496 488 496 ASP ASP B . n 
B 1 497 THR 497 489 497 THR THR B . n 
B 1 498 ARG 498 490 498 ARG ARG B . n 
B 1 499 ASP 499 491 499 ASP ASP B . n 
B 1 500 PHE 500 492 500 PHE PHE B . n 
B 1 501 THR 501 493 501 THR THR B . n 
B 1 502 LYS 502 494 502 LYS LYS B . n 
B 1 503 ALA 503 495 503 ALA ALA B . n 
B 1 504 VAL 504 496 504 VAL VAL B . n 
B 1 505 ALA 505 497 505 ALA ALA B . n 
B 1 506 ALA 506 498 506 ALA ALA B . n 
B 1 507 VAL 507 499 507 VAL VAL B . n 
B 1 508 GLN 508 500 508 GLN GLN B . n 
B 1 509 LEU 509 501 509 LEU LEU B . n 
B 1 510 PRO 510 502 510 PRO PRO B . n 
B 1 511 PHE 511 503 511 PHE PHE B . n 
B 1 512 ALA 512 504 512 ALA ALA B . n 
B 1 513 ILE 513 505 513 ILE ILE B . n 
B 1 514 ARG 514 506 514 ARG ARG B . n 
B 1 515 SER 515 507 515 SER SER B . n 
B 1 516 GLY 516 508 516 GLY GLY B . n 
B 1 517 ILE 517 509 517 ILE ILE B . n 
B 1 518 HIS 518 510 518 HIS HIS B . n 
B 1 519 GLY 519 511 519 GLY GLY B . n 
B 1 520 GLN 520 512 520 GLN GLN B . n 
B 1 521 TRP 521 513 521 TRP TRP B . n 
B 1 522 ILE 522 514 522 ILE ILE B . n 
B 1 523 PRO 523 515 523 PRO PRO B . n 
B 1 524 GLY 524 516 524 GLY GLY B . n 
B 1 525 GLU 525 517 525 GLU GLU B . n 
B 1 526 VAL 526 518 526 VAL VAL B . n 
B 1 527 THR 527 519 527 THR THR B . n 
B 1 528 PRO 528 520 528 PRO PRO B . n 
B 1 529 ASP 529 521 529 ASP ASP B . n 
B 1 530 PHE 530 522 530 PHE PHE B . n 
B 1 531 GLU 531 523 531 GLU GLU B . n 
B 1 532 THR 532 524 532 THR THR B . n 
B 1 533 LYS 533 525 533 LYS LYS B . n 
B 1 534 GLY 534 526 534 GLY GLY B . n 
B 1 535 LEU 535 527 535 LEU LEU B . n 
B 1 536 VAL 536 528 536 VAL VAL B . n 
B 1 537 ASP 537 529 537 ASP ASP B . n 
B 1 538 LEU 538 530 538 LEU LEU B . n 
B 1 539 PRO 539 531 539 PRO PRO B . n 
B 1 540 LYS 540 532 540 LYS LYS B . n 
B 1 541 GLU 541 533 541 GLU GLU B . n 
B 1 542 GLU 542 534 542 GLU GLU B . n 
B 1 543 HIS 543 535 543 HIS HIS B . n 
B 1 544 TRP 544 536 544 TRP TRP B . n 
B 1 545 ALA 545 537 545 ALA ALA B . n 
B 1 546 PRO 546 538 546 PRO PRO B . n 
B 1 547 LEU 547 539 547 LEU LEU B . n 
B 1 548 SER 548 540 548 SER SER B . n 
B 1 549 GLN 549 541 549 GLN GLN B . n 
B 1 550 SER 550 542 550 SER SER B . n 
B 1 551 PRO 551 543 551 PRO PRO B . n 
B 1 552 TYR 552 544 552 TYR TYR B . n 
B 1 553 ASP 553 545 553 ASP ASP B . n 
B 1 554 PRO 554 546 554 PRO PRO B . n 
B 1 555 ASP 555 547 555 ASP ASP B . n 
B 1 556 ALA 556 548 556 ALA ALA B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 FE2 ? ? FE2 ? ? 'SUBJECT OF INVESTIGATION' ? 
2 V9L ? ? V9L ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 V9L 1   601  1   V9L 00Z A . 
D 3 FE2 1   602  1   FE2 FE  A . 
E 2 V9L 1   601  10  V9L 00Z B . 
F 3 FE2 1   602  2   FE2 FE  B . 
G 4 HOH 1   701  578 HOH HOH A . 
G 4 HOH 2   702  425 HOH HOH A . 
G 4 HOH 3   703  867 HOH HOH A . 
G 4 HOH 4   704  794 HOH HOH A . 
G 4 HOH 5   705  718 HOH HOH A . 
G 4 HOH 6   706  690 HOH HOH A . 
G 4 HOH 7   707  510 HOH HOH A . 
G 4 HOH 8   708  992 HOH HOH A . 
G 4 HOH 9   709  590 HOH HOH A . 
G 4 HOH 10  710  107 HOH HOH A . 
G 4 HOH 11  711  521 HOH HOH A . 
G 4 HOH 12  712  526 HOH HOH A . 
G 4 HOH 13  713  680 HOH HOH A . 
G 4 HOH 14  714  531 HOH HOH A . 
G 4 HOH 15  715  671 HOH HOH A . 
G 4 HOH 16  716  797 HOH HOH A . 
G 4 HOH 17  717  733 HOH HOH A . 
G 4 HOH 18  718  864 HOH HOH A . 
G 4 HOH 19  719  655 HOH HOH A . 
G 4 HOH 20  720  412 HOH HOH A . 
G 4 HOH 21  721  591 HOH HOH A . 
G 4 HOH 22  722  743 HOH HOH A . 
G 4 HOH 23  723  318 HOH HOH A . 
G 4 HOH 24  724  807 HOH HOH A . 
G 4 HOH 25  725  150 HOH HOH A . 
G 4 HOH 26  726  987 HOH HOH A . 
G 4 HOH 27  727  86  HOH HOH A . 
G 4 HOH 28  728  212 HOH HOH A . 
G 4 HOH 29  729  240 HOH HOH A . 
G 4 HOH 30  730  900 HOH HOH A . 
G 4 HOH 31  731  366 HOH HOH A . 
G 4 HOH 32  732  572 HOH HOH A . 
G 4 HOH 33  733  28  HOH HOH A . 
G 4 HOH 34  734  849 HOH HOH A . 
G 4 HOH 35  735  784 HOH HOH A . 
G 4 HOH 36  736  343 HOH HOH A . 
G 4 HOH 37  737  699 HOH HOH A . 
G 4 HOH 38  738  136 HOH HOH A . 
G 4 HOH 39  739  12  HOH HOH A . 
G 4 HOH 40  740  338 HOH HOH A . 
G 4 HOH 41  741  156 HOH HOH A . 
G 4 HOH 42  742  345 HOH HOH A . 
G 4 HOH 43  743  164 HOH HOH A . 
G 4 HOH 44  744  634 HOH HOH A . 
G 4 HOH 45  745  709 HOH HOH A . 
G 4 HOH 46  746  10  HOH HOH A . 
G 4 HOH 47  747  760 HOH HOH A . 
G 4 HOH 48  748  43  HOH HOH A . 
G 4 HOH 49  749  471 HOH HOH A . 
G 4 HOH 50  750  841 HOH HOH A . 
G 4 HOH 51  751  190 HOH HOH A . 
G 4 HOH 52  752  3   HOH HOH A . 
G 4 HOH 53  753  382 HOH HOH A . 
G 4 HOH 54  754  234 HOH HOH A . 
G 4 HOH 55  755  368 HOH HOH A . 
G 4 HOH 56  756  223 HOH HOH A . 
G 4 HOH 57  757  204 HOH HOH A . 
G 4 HOH 58  758  364 HOH HOH A . 
G 4 HOH 59  759  746 HOH HOH A . 
G 4 HOH 60  760  14  HOH HOH A . 
G 4 HOH 61  761  796 HOH HOH A . 
G 4 HOH 62  762  115 HOH HOH A . 
G 4 HOH 63  763  285 HOH HOH A . 
G 4 HOH 64  764  440 HOH HOH A . 
G 4 HOH 65  765  532 HOH HOH A . 
G 4 HOH 66  766  57  HOH HOH A . 
G 4 HOH 67  767  449 HOH HOH A . 
G 4 HOH 68  768  892 HOH HOH A . 
G 4 HOH 69  769  291 HOH HOH A . 
G 4 HOH 70  770  830 HOH HOH A . 
G 4 HOH 71  771  489 HOH HOH A . 
G 4 HOH 72  772  593 HOH HOH A . 
G 4 HOH 73  773  217 HOH HOH A . 
G 4 HOH 74  774  764 HOH HOH A . 
G 4 HOH 75  775  474 HOH HOH A . 
G 4 HOH 76  776  558 HOH HOH A . 
G 4 HOH 77  777  203 HOH HOH A . 
G 4 HOH 78  778  236 HOH HOH A . 
G 4 HOH 79  779  295 HOH HOH A . 
G 4 HOH 80  780  96  HOH HOH A . 
G 4 HOH 81  781  994 HOH HOH A . 
G 4 HOH 82  782  75  HOH HOH A . 
G 4 HOH 83  783  323 HOH HOH A . 
G 4 HOH 84  784  68  HOH HOH A . 
G 4 HOH 85  785  544 HOH HOH A . 
G 4 HOH 86  786  543 HOH HOH A . 
G 4 HOH 87  787  304 HOH HOH A . 
G 4 HOH 88  788  803 HOH HOH A . 
G 4 HOH 89  789  358 HOH HOH A . 
G 4 HOH 90  790  725 HOH HOH A . 
G 4 HOH 91  791  271 HOH HOH A . 
G 4 HOH 92  792  982 HOH HOH A . 
G 4 HOH 93  793  4   HOH HOH A . 
G 4 HOH 94  794  110 HOH HOH A . 
G 4 HOH 95  795  64  HOH HOH A . 
G 4 HOH 96  796  913 HOH HOH A . 
G 4 HOH 97  797  72  HOH HOH A . 
G 4 HOH 98  798  221 HOH HOH A . 
G 4 HOH 99  799  51  HOH HOH A . 
G 4 HOH 100 800  192 HOH HOH A . 
G 4 HOH 101 801  881 HOH HOH A . 
G 4 HOH 102 802  135 HOH HOH A . 
G 4 HOH 103 803  781 HOH HOH A . 
G 4 HOH 104 804  116 HOH HOH A . 
G 4 HOH 105 805  577 HOH HOH A . 
G 4 HOH 106 806  504 HOH HOH A . 
G 4 HOH 107 807  677 HOH HOH A . 
G 4 HOH 108 808  482 HOH HOH A . 
G 4 HOH 109 809  656 HOH HOH A . 
G 4 HOH 110 810  498 HOH HOH A . 
G 4 HOH 111 811  766 HOH HOH A . 
G 4 HOH 112 812  551 HOH HOH A . 
G 4 HOH 113 813  83  HOH HOH A . 
G 4 HOH 114 814  871 HOH HOH A . 
G 4 HOH 115 815  187 HOH HOH A . 
G 4 HOH 116 816  894 HOH HOH A . 
G 4 HOH 117 817  461 HOH HOH A . 
G 4 HOH 118 818  215 HOH HOH A . 
G 4 HOH 119 819  816 HOH HOH A . 
G 4 HOH 120 820  53  HOH HOH A . 
G 4 HOH 121 821  377 HOH HOH A . 
G 4 HOH 122 822  458 HOH HOH A . 
G 4 HOH 123 823  280 HOH HOH A . 
G 4 HOH 124 824  61  HOH HOH A . 
G 4 HOH 125 825  162 HOH HOH A . 
G 4 HOH 126 826  479 HOH HOH A . 
G 4 HOH 127 827  350 HOH HOH A . 
G 4 HOH 128 828  454 HOH HOH A . 
G 4 HOH 129 829  105 HOH HOH A . 
G 4 HOH 130 830  58  HOH HOH A . 
G 4 HOH 131 831  359 HOH HOH A . 
G 4 HOH 132 832  173 HOH HOH A . 
G 4 HOH 133 833  93  HOH HOH A . 
G 4 HOH 134 834  76  HOH HOH A . 
G 4 HOH 135 835  34  HOH HOH A . 
G 4 HOH 136 836  46  HOH HOH A . 
G 4 HOH 137 837  985 HOH HOH A . 
G 4 HOH 138 838  21  HOH HOH A . 
G 4 HOH 139 839  45  HOH HOH A . 
G 4 HOH 140 840  460 HOH HOH A . 
G 4 HOH 141 841  315 HOH HOH A . 
G 4 HOH 142 842  629 HOH HOH A . 
G 4 HOH 143 843  565 HOH HOH A . 
G 4 HOH 144 844  980 HOH HOH A . 
G 4 HOH 145 845  873 HOH HOH A . 
G 4 HOH 146 846  663 HOH HOH A . 
G 4 HOH 147 847  455 HOH HOH A . 
G 4 HOH 148 848  213 HOH HOH A . 
G 4 HOH 149 849  542 HOH HOH A . 
G 4 HOH 150 850  868 HOH HOH A . 
G 4 HOH 151 851  899 HOH HOH A . 
G 4 HOH 152 852  139 HOH HOH A . 
G 4 HOH 153 853  759 HOH HOH A . 
G 4 HOH 154 854  30  HOH HOH A . 
G 4 HOH 155 855  818 HOH HOH A . 
G 4 HOH 156 856  245 HOH HOH A . 
G 4 HOH 157 857  353 HOH HOH A . 
G 4 HOH 158 858  168 HOH HOH A . 
G 4 HOH 159 859  481 HOH HOH A . 
G 4 HOH 160 860  689 HOH HOH A . 
G 4 HOH 161 861  211 HOH HOH A . 
G 4 HOH 162 862  228 HOH HOH A . 
G 4 HOH 163 863  493 HOH HOH A . 
G 4 HOH 164 864  410 HOH HOH A . 
G 4 HOH 165 865  275 HOH HOH A . 
G 4 HOH 166 866  800 HOH HOH A . 
G 4 HOH 167 867  520 HOH HOH A . 
G 4 HOH 168 868  716 HOH HOH A . 
G 4 HOH 169 869  351 HOH HOH A . 
G 4 HOH 170 870  9   HOH HOH A . 
G 4 HOH 171 871  265 HOH HOH A . 
G 4 HOH 172 872  862 HOH HOH A . 
G 4 HOH 173 873  180 HOH HOH A . 
G 4 HOH 174 874  362 HOH HOH A . 
G 4 HOH 175 875  16  HOH HOH A . 
G 4 HOH 176 876  480 HOH HOH A . 
G 4 HOH 177 877  456 HOH HOH A . 
G 4 HOH 178 878  124 HOH HOH A . 
G 4 HOH 179 879  129 HOH HOH A . 
G 4 HOH 180 880  114 HOH HOH A . 
G 4 HOH 181 881  95  HOH HOH A . 
G 4 HOH 182 882  853 HOH HOH A . 
G 4 HOH 183 883  69  HOH HOH A . 
G 4 HOH 184 884  5   HOH HOH A . 
G 4 HOH 185 885  44  HOH HOH A . 
G 4 HOH 186 886  15  HOH HOH A . 
G 4 HOH 187 887  6   HOH HOH A . 
G 4 HOH 188 888  157 HOH HOH A . 
G 4 HOH 189 889  536 HOH HOH A . 
G 4 HOH 190 890  826 HOH HOH A . 
G 4 HOH 191 891  553 HOH HOH A . 
G 4 HOH 192 892  255 HOH HOH A . 
G 4 HOH 193 893  836 HOH HOH A . 
G 4 HOH 194 894  35  HOH HOH A . 
G 4 HOH 195 895  774 HOH HOH A . 
G 4 HOH 196 896  409 HOH HOH A . 
G 4 HOH 197 897  263 HOH HOH A . 
G 4 HOH 198 898  310 HOH HOH A . 
G 4 HOH 199 899  451 HOH HOH A . 
G 4 HOH 200 900  687 HOH HOH A . 
G 4 HOH 201 901  492 HOH HOH A . 
G 4 HOH 202 902  889 HOH HOH A . 
G 4 HOH 203 903  559 HOH HOH A . 
G 4 HOH 204 904  989 HOH HOH A . 
G 4 HOH 205 905  89  HOH HOH A . 
G 4 HOH 206 906  316 HOH HOH A . 
G 4 HOH 207 907  777 HOH HOH A . 
G 4 HOH 208 908  726 HOH HOH A . 
G 4 HOH 209 909  434 HOH HOH A . 
G 4 HOH 210 910  158 HOH HOH A . 
G 4 HOH 211 911  167 HOH HOH A . 
G 4 HOH 212 912  576 HOH HOH A . 
G 4 HOH 213 913  610 HOH HOH A . 
G 4 HOH 214 914  243 HOH HOH A . 
G 4 HOH 215 915  90  HOH HOH A . 
G 4 HOH 216 916  406 HOH HOH A . 
G 4 HOH 217 917  522 HOH HOH A . 
G 4 HOH 218 918  670 HOH HOH A . 
G 4 HOH 219 919  299 HOH HOH A . 
G 4 HOH 220 920  664 HOH HOH A . 
G 4 HOH 221 921  821 HOH HOH A . 
G 4 HOH 222 922  87  HOH HOH A . 
G 4 HOH 223 923  823 HOH HOH A . 
G 4 HOH 224 924  561 HOH HOH A . 
G 4 HOH 225 925  756 HOH HOH A . 
G 4 HOH 226 926  305 HOH HOH A . 
G 4 HOH 227 927  732 HOH HOH A . 
G 4 HOH 228 928  326 HOH HOH A . 
G 4 HOH 229 929  441 HOH HOH A . 
G 4 HOH 230 930  958 HOH HOH A . 
G 4 HOH 231 931  247 HOH HOH A . 
G 4 HOH 232 932  48  HOH HOH A . 
G 4 HOH 233 933  912 HOH HOH A . 
G 4 HOH 234 934  717 HOH HOH A . 
G 4 HOH 235 935  174 HOH HOH A . 
G 4 HOH 236 936  206 HOH HOH A . 
G 4 HOH 237 937  294 HOH HOH A . 
G 4 HOH 238 938  205 HOH HOH A . 
G 4 HOH 239 939  851 HOH HOH A . 
G 4 HOH 240 940  120 HOH HOH A . 
G 4 HOH 241 941  840 HOH HOH A . 
G 4 HOH 242 942  738 HOH HOH A . 
G 4 HOH 243 943  519 HOH HOH A . 
G 4 HOH 244 944  837 HOH HOH A . 
G 4 HOH 245 945  82  HOH HOH A . 
G 4 HOH 246 946  515 HOH HOH A . 
G 4 HOH 247 947  714 HOH HOH A . 
G 4 HOH 248 948  78  HOH HOH A . 
G 4 HOH 249 949  979 HOH HOH A . 
G 4 HOH 250 950  39  HOH HOH A . 
G 4 HOH 251 951  251 HOH HOH A . 
G 4 HOH 252 952  360 HOH HOH A . 
G 4 HOH 253 953  820 HOH HOH A . 
G 4 HOH 254 954  839 HOH HOH A . 
G 4 HOH 255 955  983 HOH HOH A . 
G 4 HOH 256 956  445 HOH HOH A . 
G 4 HOH 257 957  437 HOH HOH A . 
G 4 HOH 258 958  7   HOH HOH A . 
G 4 HOH 259 959  172 HOH HOH A . 
G 4 HOH 260 960  77  HOH HOH A . 
G 4 HOH 261 961  846 HOH HOH A . 
G 4 HOH 262 962  721 HOH HOH A . 
G 4 HOH 263 963  94  HOH HOH A . 
G 4 HOH 264 964  2   HOH HOH A . 
G 4 HOH 265 965  282 HOH HOH A . 
G 4 HOH 266 966  370 HOH HOH A . 
G 4 HOH 267 967  662 HOH HOH A . 
G 4 HOH 268 968  564 HOH HOH A . 
G 4 HOH 269 969  281 HOH HOH A . 
G 4 HOH 270 970  198 HOH HOH A . 
G 4 HOH 271 971  735 HOH HOH A . 
G 4 HOH 272 972  765 HOH HOH A . 
G 4 HOH 273 973  603 HOH HOH A . 
G 4 HOH 274 974  36  HOH HOH A . 
G 4 HOH 275 975  8   HOH HOH A . 
G 4 HOH 276 976  225 HOH HOH A . 
G 4 HOH 277 977  901 HOH HOH A . 
G 4 HOH 278 978  722 HOH HOH A . 
G 4 HOH 279 979  679 HOH HOH A . 
G 4 HOH 280 980  809 HOH HOH A . 
G 4 HOH 281 981  132 HOH HOH A . 
G 4 HOH 282 982  500 HOH HOH A . 
G 4 HOH 283 983  177 HOH HOH A . 
G 4 HOH 284 984  457 HOH HOH A . 
G 4 HOH 285 985  525 HOH HOH A . 
G 4 HOH 286 986  195 HOH HOH A . 
G 4 HOH 287 987  142 HOH HOH A . 
G 4 HOH 288 988  365 HOH HOH A . 
G 4 HOH 289 989  371 HOH HOH A . 
G 4 HOH 290 990  428 HOH HOH A . 
G 4 HOH 291 991  540 HOH HOH A . 
G 4 HOH 292 992  974 HOH HOH A . 
G 4 HOH 293 993  352 HOH HOH A . 
G 4 HOH 294 994  673 HOH HOH A . 
G 4 HOH 295 995  331 HOH HOH A . 
G 4 HOH 296 996  218 HOH HOH A . 
G 4 HOH 297 997  253 HOH HOH A . 
G 4 HOH 298 998  67  HOH HOH A . 
G 4 HOH 299 999  146 HOH HOH A . 
G 4 HOH 300 1000 88  HOH HOH A . 
G 4 HOH 301 1001 413 HOH HOH A . 
G 4 HOH 302 1002 644 HOH HOH A . 
G 4 HOH 303 1003 686 HOH HOH A . 
G 4 HOH 304 1004 152 HOH HOH A . 
G 4 HOH 305 1005 54  HOH HOH A . 
G 4 HOH 306 1006 497 HOH HOH A . 
G 4 HOH 307 1007 420 HOH HOH A . 
G 4 HOH 308 1008 131 HOH HOH A . 
G 4 HOH 309 1009 750 HOH HOH A . 
G 4 HOH 310 1010 199 HOH HOH A . 
G 4 HOH 311 1011 825 HOH HOH A . 
G 4 HOH 312 1012 681 HOH HOH A . 
G 4 HOH 313 1013 148 HOH HOH A . 
G 4 HOH 314 1014 119 HOH HOH A . 
G 4 HOH 315 1015 978 HOH HOH A . 
G 4 HOH 316 1016 571 HOH HOH A . 
G 4 HOH 317 1017 24  HOH HOH A . 
G 4 HOH 318 1018 99  HOH HOH A . 
G 4 HOH 319 1019 339 HOH HOH A . 
G 4 HOH 320 1020 427 HOH HOH A . 
G 4 HOH 321 1021 267 HOH HOH A . 
G 4 HOH 322 1022 847 HOH HOH A . 
G 4 HOH 323 1023 171 HOH HOH A . 
G 4 HOH 324 1024 667 HOH HOH A . 
G 4 HOH 325 1025 762 HOH HOH A . 
G 4 HOH 326 1026 730 HOH HOH A . 
G 4 HOH 327 1027 298 HOH HOH A . 
G 4 HOH 328 1028 185 HOH HOH A . 
G 4 HOH 329 1029 624 HOH HOH A . 
G 4 HOH 330 1030 13  HOH HOH A . 
G 4 HOH 331 1031 505 HOH HOH A . 
G 4 HOH 332 1032 701 HOH HOH A . 
G 4 HOH 333 1033 252 HOH HOH A . 
G 4 HOH 334 1034 376 HOH HOH A . 
G 4 HOH 335 1035 675 HOH HOH A . 
G 4 HOH 336 1036 880 HOH HOH A . 
G 4 HOH 337 1037 340 HOH HOH A . 
G 4 HOH 338 1038 747 HOH HOH A . 
G 4 HOH 339 1039 279 HOH HOH A . 
G 4 HOH 340 1040 293 HOH HOH A . 
G 4 HOH 341 1041 342 HOH HOH A . 
G 4 HOH 342 1042 374 HOH HOH A . 
G 4 HOH 343 1043 650 HOH HOH A . 
G 4 HOH 344 1044 828 HOH HOH A . 
G 4 HOH 345 1045 856 HOH HOH A . 
G 4 HOH 346 1046 637 HOH HOH A . 
G 4 HOH 347 1047 143 HOH HOH A . 
G 4 HOH 348 1048 314 HOH HOH A . 
G 4 HOH 349 1049 548 HOH HOH A . 
G 4 HOH 350 1050 229 HOH HOH A . 
G 4 HOH 351 1051 560 HOH HOH A . 
G 4 HOH 352 1052 798 HOH HOH A . 
G 4 HOH 353 1053 97  HOH HOH A . 
G 4 HOH 354 1054 788 HOH HOH A . 
G 4 HOH 355 1055 584 HOH HOH A . 
G 4 HOH 356 1056 911 HOH HOH A . 
G 4 HOH 357 1057 904 HOH HOH A . 
G 4 HOH 358 1058 745 HOH HOH A . 
G 4 HOH 359 1059 439 HOH HOH A . 
G 4 HOH 360 1060 876 HOH HOH A . 
G 4 HOH 361 1061 485 HOH HOH A . 
G 4 HOH 362 1062 848 HOH HOH A . 
G 4 HOH 363 1063 708 HOH HOH A . 
G 4 HOH 364 1064 424 HOH HOH A . 
G 4 HOH 365 1065 63  HOH HOH A . 
G 4 HOH 366 1066 587 HOH HOH A . 
G 4 HOH 367 1067 309 HOH HOH A . 
G 4 HOH 368 1068 812 HOH HOH A . 
G 4 HOH 369 1069 744 HOH HOH A . 
G 4 HOH 370 1070 769 HOH HOH A . 
G 4 HOH 371 1071 919 HOH HOH A . 
G 4 HOH 372 1072 433 HOH HOH A . 
G 4 HOH 373 1073 939 HOH HOH A . 
G 4 HOH 374 1074 741 HOH HOH A . 
G 4 HOH 375 1075 811 HOH HOH A . 
G 4 HOH 376 1076 630 HOH HOH A . 
G 4 HOH 377 1077 692 HOH HOH A . 
G 4 HOH 378 1078 344 HOH HOH A . 
G 4 HOH 379 1079 945 HOH HOH A . 
G 4 HOH 380 1080 937 HOH HOH A . 
G 4 HOH 381 1081 691 HOH HOH A . 
G 4 HOH 382 1082 758 HOH HOH A . 
G 4 HOH 383 1083 568 HOH HOH A . 
G 4 HOH 384 1084 778 HOH HOH A . 
G 4 HOH 385 1085 842 HOH HOH A . 
G 4 HOH 386 1086 538 HOH HOH A . 
G 4 HOH 387 1087 954 HOH HOH A . 
G 4 HOH 388 1088 940 HOH HOH A . 
G 4 HOH 389 1089 651 HOH HOH A . 
G 4 HOH 390 1090 666 HOH HOH A . 
G 4 HOH 391 1091 574 HOH HOH A . 
G 4 HOH 392 1092 813 HOH HOH A . 
G 4 HOH 393 1093 771 HOH HOH A . 
G 4 HOH 394 1094 874 HOH HOH A . 
G 4 HOH 395 1095 915 HOH HOH A . 
G 4 HOH 396 1096 925 HOH HOH A . 
G 4 HOH 397 1097 905 HOH HOH A . 
G 4 HOH 398 1098 401 HOH HOH A . 
G 4 HOH 399 1099 121 HOH HOH A . 
G 4 HOH 400 1100 838 HOH HOH A . 
G 4 HOH 401 1101 444 HOH HOH A . 
G 4 HOH 402 1102 975 HOH HOH A . 
G 4 HOH 403 1103 909 HOH HOH A . 
G 4 HOH 404 1104 477 HOH HOH A . 
G 4 HOH 405 1105 776 HOH HOH A . 
G 4 HOH 406 1106 949 HOH HOH A . 
G 4 HOH 407 1107 941 HOH HOH A . 
G 4 HOH 408 1108 385 HOH HOH A . 
G 4 HOH 409 1109 659 HOH HOH A . 
G 4 HOH 410 1110 936 HOH HOH A . 
G 4 HOH 411 1111 976 HOH HOH A . 
G 4 HOH 412 1112 266 HOH HOH A . 
G 4 HOH 413 1113 635 HOH HOH A . 
G 4 HOH 414 1114 423 HOH HOH A . 
G 4 HOH 415 1115 890 HOH HOH A . 
G 4 HOH 416 1116 895 HOH HOH A . 
G 4 HOH 417 1117 957 HOH HOH A . 
G 4 HOH 418 1118 934 HOH HOH A . 
G 4 HOH 419 1119 388 HOH HOH A . 
G 4 HOH 420 1120 962 HOH HOH A . 
G 4 HOH 421 1121 539 HOH HOH A . 
G 4 HOH 422 1122 602 HOH HOH A . 
G 4 HOH 423 1123 611 HOH HOH A . 
G 4 HOH 424 1124 720 HOH HOH A . 
G 4 HOH 425 1125 436 HOH HOH A . 
G 4 HOH 426 1126 604 HOH HOH A . 
G 4 HOH 427 1127 601 HOH HOH A . 
G 4 HOH 428 1128 533 HOH HOH A . 
G 4 HOH 429 1129 739 HOH HOH A . 
G 4 HOH 430 1130 529 HOH HOH A . 
G 4 HOH 431 1131 956 HOH HOH A . 
G 4 HOH 432 1132 506 HOH HOH A . 
G 4 HOH 433 1133 472 HOH HOH A . 
G 4 HOH 434 1134 772 HOH HOH A . 
G 4 HOH 435 1135 953 HOH HOH A . 
G 4 HOH 436 1136 935 HOH HOH A . 
G 4 HOH 437 1137 783 HOH HOH A . 
G 4 HOH 438 1138 517 HOH HOH A . 
G 4 HOH 439 1139 683 HOH HOH A . 
G 4 HOH 440 1140 242 HOH HOH A . 
G 4 HOH 441 1141 903 HOH HOH A . 
G 4 HOH 442 1142 802 HOH HOH A . 
G 4 HOH 443 1143 827 HOH HOH A . 
G 4 HOH 444 1144 596 HOH HOH A . 
G 4 HOH 445 1145 452 HOH HOH A . 
G 4 HOH 446 1146 503 HOH HOH A . 
G 4 HOH 447 1147 888 HOH HOH A . 
G 4 HOH 448 1148 648 HOH HOH A . 
G 4 HOH 449 1149 814 HOH HOH A . 
G 4 HOH 450 1150 770 HOH HOH A . 
G 4 HOH 451 1151 751 HOH HOH A . 
G 4 HOH 452 1152 682 HOH HOH A . 
G 4 HOH 453 1153 918 HOH HOH A . 
G 4 HOH 454 1154 595 HOH HOH A . 
G 4 HOH 455 1155 857 HOH HOH A . 
G 4 HOH 456 1156 511 HOH HOH A . 
G 4 HOH 457 1157 661 HOH HOH A . 
G 4 HOH 458 1158 430 HOH HOH A . 
G 4 HOH 459 1159 527 HOH HOH A . 
G 4 HOH 460 1160 893 HOH HOH A . 
G 4 HOH 461 1161 483 HOH HOH A . 
G 4 HOH 462 1162 795 HOH HOH A . 
G 4 HOH 463 1163 928 HOH HOH A . 
G 4 HOH 464 1164 965 HOH HOH A . 
G 4 HOH 465 1165 643 HOH HOH A . 
G 4 HOH 466 1166 929 HOH HOH A . 
G 4 HOH 467 1167 569 HOH HOH A . 
G 4 HOH 468 1168 822 HOH HOH A . 
G 4 HOH 469 1169 885 HOH HOH A . 
G 4 HOH 470 1170 669 HOH HOH A . 
G 4 HOH 471 1171 955 HOH HOH A . 
G 4 HOH 472 1172 432 HOH HOH A . 
G 4 HOH 473 1173 462 HOH HOH A . 
G 4 HOH 474 1174 906 HOH HOH A . 
G 4 HOH 475 1175 557 HOH HOH A . 
G 4 HOH 476 1176 665 HOH HOH A . 
G 4 HOH 477 1177 879 HOH HOH A . 
G 4 HOH 478 1178 882 HOH HOH A . 
G 4 HOH 479 1179 833 HOH HOH A . 
G 4 HOH 480 1180 554 HOH HOH A . 
G 4 HOH 481 1181 932 HOH HOH A . 
G 4 HOH 482 1182 860 HOH HOH A . 
G 4 HOH 483 1183 907 HOH HOH A . 
G 4 HOH 484 1184 728 HOH HOH A . 
G 4 HOH 485 1185 711 HOH HOH A . 
G 4 HOH 486 1186 967 HOH HOH A . 
H 4 HOH 1   701  599 HOH HOH B . 
H 4 HOH 2   702  678 HOH HOH B . 
H 4 HOH 3   703  288 HOH HOH B . 
H 4 HOH 4   704  707 HOH HOH B . 
H 4 HOH 5   705  695 HOH HOH B . 
H 4 HOH 6   706  705 HOH HOH B . 
H 4 HOH 7   707  470 HOH HOH B . 
H 4 HOH 8   708  411 HOH HOH B . 
H 4 HOH 9   709  516 HOH HOH B . 
H 4 HOH 10  710  419 HOH HOH B . 
H 4 HOH 11  711  447 HOH HOH B . 
H 4 HOH 12  712  319 HOH HOH B . 
H 4 HOH 13  713  476 HOH HOH B . 
H 4 HOH 14  714  898 HOH HOH B . 
H 4 HOH 15  715  734 HOH HOH B . 
H 4 HOH 16  716  991 HOH HOH B . 
H 4 HOH 17  717  20  HOH HOH B . 
H 4 HOH 18  718  18  HOH HOH B . 
H 4 HOH 19  719  98  HOH HOH B . 
H 4 HOH 20  720  672 HOH HOH B . 
H 4 HOH 21  721  896 HOH HOH B . 
H 4 HOH 22  722  361 HOH HOH B . 
H 4 HOH 23  723  32  HOH HOH B . 
H 4 HOH 24  724  566 HOH HOH B . 
H 4 HOH 25  725  111 HOH HOH B . 
H 4 HOH 26  726  196 HOH HOH B . 
H 4 HOH 27  727  197 HOH HOH B . 
H 4 HOH 28  728  416 HOH HOH B . 
H 4 HOH 29  729  393 HOH HOH B . 
H 4 HOH 30  730  262 HOH HOH B . 
H 4 HOH 31  731  400 HOH HOH B . 
H 4 HOH 32  732  523 HOH HOH B . 
H 4 HOH 33  733  117 HOH HOH B . 
H 4 HOH 34  734  891 HOH HOH B . 
H 4 HOH 35  735  74  HOH HOH B . 
H 4 HOH 36  736  570 HOH HOH B . 
H 4 HOH 37  737  290 HOH HOH B . 
H 4 HOH 38  738  264 HOH HOH B . 
H 4 HOH 39  739  52  HOH HOH B . 
H 4 HOH 40  740  62  HOH HOH B . 
H 4 HOH 41  741  311 HOH HOH B . 
H 4 HOH 42  742  902 HOH HOH B . 
H 4 HOH 43  743  348 HOH HOH B . 
H 4 HOH 44  744  346 HOH HOH B . 
H 4 HOH 45  745  514 HOH HOH B . 
H 4 HOH 46  746  248 HOH HOH B . 
H 4 HOH 47  747  276 HOH HOH B . 
H 4 HOH 48  748  286 HOH HOH B . 
H 4 HOH 49  749  59  HOH HOH B . 
H 4 HOH 50  750  494 HOH HOH B . 
H 4 HOH 51  751  396 HOH HOH B . 
H 4 HOH 52  752  405 HOH HOH B . 
H 4 HOH 53  753  307 HOH HOH B . 
H 4 HOH 54  754  81  HOH HOH B . 
H 4 HOH 55  755  612 HOH HOH B . 
H 4 HOH 56  756  31  HOH HOH B . 
H 4 HOH 57  757  347 HOH HOH B . 
H 4 HOH 58  758  189 HOH HOH B . 
H 4 HOH 59  759  620 HOH HOH B . 
H 4 HOH 60  760  327 HOH HOH B . 
H 4 HOH 61  761  391 HOH HOH B . 
H 4 HOH 62  762  219 HOH HOH B . 
H 4 HOH 63  763  308 HOH HOH B . 
H 4 HOH 64  764  395 HOH HOH B . 
H 4 HOH 65  765  684 HOH HOH B . 
H 4 HOH 66  766  367 HOH HOH B . 
H 4 HOH 67  767  615 HOH HOH B . 
H 4 HOH 68  768  407 HOH HOH B . 
H 4 HOH 69  769  399 HOH HOH B . 
H 4 HOH 70  770  804 HOH HOH B . 
H 4 HOH 71  771  292 HOH HOH B . 
H 4 HOH 72  772  448 HOH HOH B . 
H 4 HOH 73  773  176 HOH HOH B . 
H 4 HOH 74  774  768 HOH HOH B . 
H 4 HOH 75  775  786 HOH HOH B . 
H 4 HOH 76  776  815 HOH HOH B . 
H 4 HOH 77  777  597 HOH HOH B . 
H 4 HOH 78  778  563 HOH HOH B . 
H 4 HOH 79  779  512 HOH HOH B . 
H 4 HOH 80  780  641 HOH HOH B . 
H 4 HOH 81  781  313 HOH HOH B . 
H 4 HOH 82  782  964 HOH HOH B . 
H 4 HOH 83  783  763 HOH HOH B . 
H 4 HOH 84  784  638 HOH HOH B . 
H 4 HOH 85  785  91  HOH HOH B . 
H 4 HOH 86  786  582 HOH HOH B . 
H 4 HOH 87  787  133 HOH HOH B . 
H 4 HOH 88  788  883 HOH HOH B . 
H 4 HOH 89  789  866 HOH HOH B . 
H 4 HOH 90  790  49  HOH HOH B . 
H 4 HOH 91  791  194 HOH HOH B . 
H 4 HOH 92  792  579 HOH HOH B . 
H 4 HOH 93  793  33  HOH HOH B . 
H 4 HOH 94  794  147 HOH HOH B . 
H 4 HOH 95  795  698 HOH HOH B . 
H 4 HOH 96  796  580 HOH HOH B . 
H 4 HOH 97  797  123 HOH HOH B . 
H 4 HOH 98  798  986 HOH HOH B . 
H 4 HOH 99  799  922 HOH HOH B . 
H 4 HOH 100 800  977 HOH HOH B . 
H 4 HOH 101 801  151 HOH HOH B . 
H 4 HOH 102 802  389 HOH HOH B . 
H 4 HOH 103 803  27  HOH HOH B . 
H 4 HOH 104 804  417 HOH HOH B . 
H 4 HOH 105 805  312 HOH HOH B . 
H 4 HOH 106 806  42  HOH HOH B . 
H 4 HOH 107 807  284 HOH HOH B . 
H 4 HOH 108 808  297 HOH HOH B . 
H 4 HOH 109 809  435 HOH HOH B . 
H 4 HOH 110 810  487 HOH HOH B . 
H 4 HOH 111 811  878 HOH HOH B . 
H 4 HOH 112 812  270 HOH HOH B . 
H 4 HOH 113 813  60  HOH HOH B . 
H 4 HOH 114 814  668 HOH HOH B . 
H 4 HOH 115 815  250 HOH HOH B . 
H 4 HOH 116 816  336 HOH HOH B . 
H 4 HOH 117 817  773 HOH HOH B . 
H 4 HOH 118 818  438 HOH HOH B . 
H 4 HOH 119 819  550 HOH HOH B . 
H 4 HOH 120 820  652 HOH HOH B . 
H 4 HOH 121 821  246 HOH HOH B . 
H 4 HOH 122 822  706 HOH HOH B . 
H 4 HOH 123 823  154 HOH HOH B . 
H 4 HOH 124 824  65  HOH HOH B . 
H 4 HOH 125 825  235 HOH HOH B . 
H 4 HOH 126 826  126 HOH HOH B . 
H 4 HOH 127 827  155 HOH HOH B . 
H 4 HOH 128 828  226 HOH HOH B . 
H 4 HOH 129 829  817 HOH HOH B . 
H 4 HOH 130 830  153 HOH HOH B . 
H 4 HOH 131 831  306 HOH HOH B . 
H 4 HOH 132 832  40  HOH HOH B . 
H 4 HOH 133 833  674 HOH HOH B . 
H 4 HOH 134 834  631 HOH HOH B . 
H 4 HOH 135 835  639 HOH HOH B . 
H 4 HOH 136 836  490 HOH HOH B . 
H 4 HOH 137 837  254 HOH HOH B . 
H 4 HOH 138 838  179 HOH HOH B . 
H 4 HOH 139 839  585 HOH HOH B . 
H 4 HOH 140 840  216 HOH HOH B . 
H 4 HOH 141 841  625 HOH HOH B . 
H 4 HOH 142 842  712 HOH HOH B . 
H 4 HOH 143 843  1   HOH HOH B . 
H 4 HOH 144 844  383 HOH HOH B . 
H 4 HOH 145 845  623 HOH HOH B . 
H 4 HOH 146 846  694 HOH HOH B . 
H 4 HOH 147 847  249 HOH HOH B . 
H 4 HOH 148 848  101 HOH HOH B . 
H 4 HOH 149 849  79  HOH HOH B . 
H 4 HOH 150 850  300 HOH HOH B . 
H 4 HOH 151 851  321 HOH HOH B . 
H 4 HOH 152 852  330 HOH HOH B . 
H 4 HOH 153 853  429 HOH HOH B . 
H 4 HOH 154 854  333 HOH HOH B . 
H 4 HOH 155 855  222 HOH HOH B . 
H 4 HOH 156 856  166 HOH HOH B . 
H 4 HOH 157 857  260 HOH HOH B . 
H 4 HOH 158 858  421 HOH HOH B . 
H 4 HOH 159 859  354 HOH HOH B . 
H 4 HOH 160 860  622 HOH HOH B . 
H 4 HOH 161 861  397 HOH HOH B . 
H 4 HOH 162 862  375 HOH HOH B . 
H 4 HOH 163 863  404 HOH HOH B . 
H 4 HOH 164 864  535 HOH HOH B . 
H 4 HOH 165 865  50  HOH HOH B . 
H 4 HOH 166 866  537 HOH HOH B . 
H 4 HOH 167 867  858 HOH HOH B . 
H 4 HOH 168 868  47  HOH HOH B . 
H 4 HOH 169 869  761 HOH HOH B . 
H 4 HOH 170 870  184 HOH HOH B . 
H 4 HOH 171 871  633 HOH HOH B . 
H 4 HOH 172 872  546 HOH HOH B . 
H 4 HOH 173 873  496 HOH HOH B . 
H 4 HOH 174 874  239 HOH HOH B . 
H 4 HOH 175 875  988 HOH HOH B . 
H 4 HOH 176 876  379 HOH HOH B . 
H 4 HOH 177 877  617 HOH HOH B . 
H 4 HOH 178 878  19  HOH HOH B . 
H 4 HOH 179 879  11  HOH HOH B . 
H 4 HOH 180 880  268 HOH HOH B . 
H 4 HOH 181 881  102 HOH HOH B . 
H 4 HOH 182 882  640 HOH HOH B . 
H 4 HOH 183 883  209 HOH HOH B . 
H 4 HOH 184 884  731 HOH HOH B . 
H 4 HOH 185 885  259 HOH HOH B . 
H 4 HOH 186 886  233 HOH HOH B . 
H 4 HOH 187 887  70  HOH HOH B . 
H 4 HOH 188 888  459 HOH HOH B . 
H 4 HOH 189 889  38  HOH HOH B . 
H 4 HOH 190 890  328 HOH HOH B . 
H 4 HOH 191 891  402 HOH HOH B . 
H 4 HOH 192 892  169 HOH HOH B . 
H 4 HOH 193 893  127 HOH HOH B . 
H 4 HOH 194 894  175 HOH HOH B . 
H 4 HOH 195 895  990 HOH HOH B . 
H 4 HOH 196 896  657 HOH HOH B . 
H 4 HOH 197 897  801 HOH HOH B . 
H 4 HOH 198 898  71  HOH HOH B . 
H 4 HOH 199 899  636 HOH HOH B . 
H 4 HOH 200 900  442 HOH HOH B . 
H 4 HOH 201 901  170 HOH HOH B . 
H 4 HOH 202 902  109 HOH HOH B . 
H 4 HOH 203 903  507 HOH HOH B . 
H 4 HOH 204 904  80  HOH HOH B . 
H 4 HOH 205 905  140 HOH HOH B . 
H 4 HOH 206 906  181 HOH HOH B . 
H 4 HOH 207 907  996 HOH HOH B . 
H 4 HOH 208 908  381 HOH HOH B . 
H 4 HOH 209 909  112 HOH HOH B . 
H 4 HOH 210 910  654 HOH HOH B . 
H 4 HOH 211 911  647 HOH HOH B . 
H 4 HOH 212 912  161 HOH HOH B . 
H 4 HOH 213 913  122 HOH HOH B . 
H 4 HOH 214 914  403 HOH HOH B . 
H 4 HOH 215 915  697 HOH HOH B . 
H 4 HOH 216 916  289 HOH HOH B . 
H 4 HOH 217 917  160 HOH HOH B . 
H 4 HOH 218 918  556 HOH HOH B . 
H 4 HOH 219 919  149 HOH HOH B . 
H 4 HOH 220 920  224 HOH HOH B . 
H 4 HOH 221 921  84  HOH HOH B . 
H 4 HOH 222 922  466 HOH HOH B . 
H 4 HOH 223 923  380 HOH HOH B . 
H 4 HOH 224 924  626 HOH HOH B . 
H 4 HOH 225 925  258 HOH HOH B . 
H 4 HOH 226 926  178 HOH HOH B . 
H 4 HOH 227 927  56  HOH HOH B . 
H 4 HOH 228 928  332 HOH HOH B . 
H 4 HOH 229 929  201 HOH HOH B . 
H 4 HOH 230 930  509 HOH HOH B . 
H 4 HOH 231 931  606 HOH HOH B . 
H 4 HOH 232 932  214 HOH HOH B . 
H 4 HOH 233 933  426 HOH HOH B . 
H 4 HOH 234 934  141 HOH HOH B . 
H 4 HOH 235 935  227 HOH HOH B . 
H 4 HOH 236 936  182 HOH HOH B . 
H 4 HOH 237 937  159 HOH HOH B . 
H 4 HOH 238 938  562 HOH HOH B . 
H 4 HOH 239 939  106 HOH HOH B . 
H 4 HOH 240 940  302 HOH HOH B . 
H 4 HOH 241 941  805 HOH HOH B . 
H 4 HOH 242 942  356 HOH HOH B . 
H 4 HOH 243 943  128 HOH HOH B . 
H 4 HOH 244 944  495 HOH HOH B . 
H 4 HOH 245 945  719 HOH HOH B . 
H 4 HOH 246 946  103 HOH HOH B . 
H 4 HOH 247 947  386 HOH HOH B . 
H 4 HOH 248 948  431 HOH HOH B . 
H 4 HOH 249 949  793 HOH HOH B . 
H 4 HOH 250 950  193 HOH HOH B . 
H 4 HOH 251 951  753 HOH HOH B . 
H 4 HOH 252 952  337 HOH HOH B . 
H 4 HOH 253 953  808 HOH HOH B . 
H 4 HOH 254 954  513 HOH HOH B . 
H 4 HOH 255 955  910 HOH HOH B . 
H 4 HOH 256 956  465 HOH HOH B . 
H 4 HOH 257 957  272 HOH HOH B . 
H 4 HOH 258 958  501 HOH HOH B . 
H 4 HOH 259 959  41  HOH HOH B . 
H 4 HOH 260 960  220 HOH HOH B . 
H 4 HOH 261 961  186 HOH HOH B . 
H 4 HOH 262 962  355 HOH HOH B . 
H 4 HOH 263 963  145 HOH HOH B . 
H 4 HOH 264 964  85  HOH HOH B . 
H 4 HOH 265 965  37  HOH HOH B . 
H 4 HOH 266 966  104 HOH HOH B . 
H 4 HOH 267 967  138 HOH HOH B . 
H 4 HOH 268 968  528 HOH HOH B . 
H 4 HOH 269 969  446 HOH HOH B . 
H 4 HOH 270 970  981 HOH HOH B . 
H 4 HOH 271 971  488 HOH HOH B . 
H 4 HOH 272 972  831 HOH HOH B . 
H 4 HOH 273 973  632 HOH HOH B . 
H 4 HOH 274 974  237 HOH HOH B . 
H 4 HOH 275 975  144 HOH HOH B . 
H 4 HOH 276 976  499 HOH HOH B . 
H 4 HOH 277 977  113 HOH HOH B . 
H 4 HOH 278 978  780 HOH HOH B . 
H 4 HOH 279 979  573 HOH HOH B . 
H 4 HOH 280 980  378 HOH HOH B . 
H 4 HOH 281 981  693 HOH HOH B . 
H 4 HOH 282 982  130 HOH HOH B . 
H 4 HOH 283 983  256 HOH HOH B . 
H 4 HOH 284 984  55  HOH HOH B . 
H 4 HOH 285 985  791 HOH HOH B . 
H 4 HOH 286 986  202 HOH HOH B . 
H 4 HOH 287 987  277 HOH HOH B . 
H 4 HOH 288 988  464 HOH HOH B . 
H 4 HOH 289 989  278 HOH HOH B . 
H 4 HOH 290 990  469 HOH HOH B . 
H 4 HOH 291 991  715 HOH HOH B . 
H 4 HOH 292 992  210 HOH HOH B . 
H 4 HOH 293 993  524 HOH HOH B . 
H 4 HOH 294 994  188 HOH HOH B . 
H 4 HOH 295 995  704 HOH HOH B . 
H 4 HOH 296 996  125 HOH HOH B . 
H 4 HOH 297 997  727 HOH HOH B . 
H 4 HOH 298 998  191 HOH HOH B . 
H 4 HOH 299 999  408 HOH HOH B . 
H 4 HOH 300 1000 700 HOH HOH B . 
H 4 HOH 301 1001 422 HOH HOH B . 
H 4 HOH 302 1002 296 HOH HOH B . 
H 4 HOH 303 1003 200 HOH HOH B . 
H 4 HOH 304 1004 418 HOH HOH B . 
H 4 HOH 305 1005 134 HOH HOH B . 
H 4 HOH 306 1006 207 HOH HOH B . 
H 4 HOH 307 1007 865 HOH HOH B . 
H 4 HOH 308 1008 552 HOH HOH B . 
H 4 HOH 309 1009 137 HOH HOH B . 
H 4 HOH 310 1010 645 HOH HOH B . 
H 4 HOH 311 1011 324 HOH HOH B . 
H 4 HOH 312 1012 25  HOH HOH B . 
H 4 HOH 313 1013 238 HOH HOH B . 
H 4 HOH 314 1014 183 HOH HOH B . 
H 4 HOH 315 1015 17  HOH HOH B . 
H 4 HOH 316 1016 92  HOH HOH B . 
H 4 HOH 317 1017 609 HOH HOH B . 
H 4 HOH 318 1018 724 HOH HOH B . 
H 4 HOH 319 1019 230 HOH HOH B . 
H 4 HOH 320 1020 320 HOH HOH B . 
H 4 HOH 321 1021 335 HOH HOH B . 
H 4 HOH 322 1022 29  HOH HOH B . 
H 4 HOH 323 1023 414 HOH HOH B . 
H 4 HOH 324 1024 736 HOH HOH B . 
H 4 HOH 325 1025 301 HOH HOH B . 
H 4 HOH 326 1026 702 HOH HOH B . 
H 4 HOH 327 1027 283 HOH HOH B . 
H 4 HOH 328 1028 392 HOH HOH B . 
H 4 HOH 329 1029 23  HOH HOH B . 
H 4 HOH 330 1030 394 HOH HOH B . 
H 4 HOH 331 1031 22  HOH HOH B . 
H 4 HOH 332 1032 545 HOH HOH B . 
H 4 HOH 333 1033 993 HOH HOH B . 
H 4 HOH 334 1034 628 HOH HOH B . 
H 4 HOH 335 1035 334 HOH HOH B . 
H 4 HOH 336 1036 875 HOH HOH B . 
H 4 HOH 337 1037 325 HOH HOH B . 
H 4 HOH 338 1038 713 HOH HOH B . 
H 4 HOH 339 1039 984 HOH HOH B . 
H 4 HOH 340 1040 749 HOH HOH B . 
H 4 HOH 341 1041 390 HOH HOH B . 
H 4 HOH 342 1042 317 HOH HOH B . 
H 4 HOH 343 1043 852 HOH HOH B . 
H 4 HOH 344 1044 502 HOH HOH B . 
H 4 HOH 345 1045 163 HOH HOH B . 
H 4 HOH 346 1046 357 HOH HOH B . 
H 4 HOH 347 1047 914 HOH HOH B . 
H 4 HOH 348 1048 660 HOH HOH B . 
H 4 HOH 349 1049 696 HOH HOH B . 
H 4 HOH 350 1050 287 HOH HOH B . 
H 4 HOH 351 1051 118 HOH HOH B . 
H 4 HOH 352 1052 824 HOH HOH B . 
H 4 HOH 353 1053 232 HOH HOH B . 
H 4 HOH 354 1054 415 HOH HOH B . 
H 4 HOH 355 1055 861 HOH HOH B . 
H 4 HOH 356 1056 845 HOH HOH B . 
H 4 HOH 357 1057 581 HOH HOH B . 
H 4 HOH 358 1058 108 HOH HOH B . 
H 4 HOH 359 1059 165 HOH HOH B . 
H 4 HOH 360 1060 467 HOH HOH B . 
H 4 HOH 361 1061 843 HOH HOH B . 
H 4 HOH 362 1062 884 HOH HOH B . 
H 4 HOH 363 1063 541 HOH HOH B . 
H 4 HOH 364 1064 618 HOH HOH B . 
H 4 HOH 365 1065 208 HOH HOH B . 
H 4 HOH 366 1066 923 HOH HOH B . 
H 4 HOH 367 1067 66  HOH HOH B . 
H 4 HOH 368 1068 274 HOH HOH B . 
H 4 HOH 369 1069 244 HOH HOH B . 
H 4 HOH 370 1070 779 HOH HOH B . 
H 4 HOH 371 1071 26  HOH HOH B . 
H 4 HOH 372 1072 491 HOH HOH B . 
H 4 HOH 373 1073 486 HOH HOH B . 
H 4 HOH 374 1074 322 HOH HOH B . 
H 4 HOH 375 1075 475 HOH HOH B . 
H 4 HOH 376 1076 73  HOH HOH B . 
H 4 HOH 377 1077 908 HOH HOH B . 
H 4 HOH 378 1078 384 HOH HOH B . 
H 4 HOH 379 1079 100 HOH HOH B . 
H 4 HOH 380 1080 646 HOH HOH B . 
H 4 HOH 381 1081 261 HOH HOH B . 
H 4 HOH 382 1082 710 HOH HOH B . 
H 4 HOH 383 1083 752 HOH HOH B . 
H 4 HOH 384 1084 785 HOH HOH B . 
H 4 HOH 385 1085 938 HOH HOH B . 
H 4 HOH 386 1086 257 HOH HOH B . 
H 4 HOH 387 1087 598 HOH HOH B . 
H 4 HOH 388 1088 363 HOH HOH B . 
H 4 HOH 389 1089 589 HOH HOH B . 
H 4 HOH 390 1090 605 HOH HOH B . 
H 4 HOH 391 1091 450 HOH HOH B . 
H 4 HOH 392 1092 792 HOH HOH B . 
H 4 HOH 393 1093 921 HOH HOH B . 
H 4 HOH 394 1094 863 HOH HOH B . 
H 4 HOH 395 1095 995 HOH HOH B . 
H 4 HOH 396 1096 241 HOH HOH B . 
H 4 HOH 397 1097 688 HOH HOH B . 
H 4 HOH 398 1098 567 HOH HOH B . 
H 4 HOH 399 1099 508 HOH HOH B . 
H 4 HOH 400 1100 806 HOH HOH B . 
H 4 HOH 401 1101 754 HOH HOH B . 
H 4 HOH 402 1102 373 HOH HOH B . 
H 4 HOH 403 1103 782 HOH HOH B . 
H 4 HOH 404 1104 627 HOH HOH B . 
H 4 HOH 405 1105 547 HOH HOH B . 
H 4 HOH 406 1106 473 HOH HOH B . 
H 4 HOH 407 1107 775 HOH HOH B . 
H 4 HOH 408 1108 588 HOH HOH B . 
H 4 HOH 409 1109 859 HOH HOH B . 
H 4 HOH 410 1110 468 HOH HOH B . 
H 4 HOH 411 1111 723 HOH HOH B . 
H 4 HOH 412 1112 789 HOH HOH B . 
H 4 HOH 413 1113 737 HOH HOH B . 
H 4 HOH 414 1114 748 HOH HOH B . 
H 4 HOH 415 1115 600 HOH HOH B . 
H 4 HOH 416 1116 835 HOH HOH B . 
H 4 HOH 417 1117 787 HOH HOH B . 
H 4 HOH 418 1118 810 HOH HOH B . 
H 4 HOH 419 1119 653 HOH HOH B . 
H 4 HOH 420 1120 613 HOH HOH B . 
H 4 HOH 421 1121 872 HOH HOH B . 
H 4 HOH 422 1122 850 HOH HOH B . 
H 4 HOH 423 1123 329 HOH HOH B . 
H 4 HOH 424 1124 742 HOH HOH B . 
H 4 HOH 425 1125 854 HOH HOH B . 
H 4 HOH 426 1126 443 HOH HOH B . 
H 4 HOH 427 1127 478 HOH HOH B . 
H 4 HOH 428 1128 942 HOH HOH B . 
H 4 HOH 429 1129 341 HOH HOH B . 
H 4 HOH 430 1130 740 HOH HOH B . 
H 4 HOH 431 1131 676 HOH HOH B . 
H 4 HOH 432 1132 966 HOH HOH B . 
H 4 HOH 433 1133 870 HOH HOH B . 
H 4 HOH 434 1134 453 HOH HOH B . 
H 4 HOH 435 1135 819 HOH HOH B . 
H 4 HOH 436 1136 685 HOH HOH B . 
H 4 HOH 437 1137 372 HOH HOH B . 
H 4 HOH 438 1138 594 HOH HOH B . 
H 4 HOH 439 1139 273 HOH HOH B . 
H 4 HOH 440 1140 869 HOH HOH B . 
H 4 HOH 441 1141 575 HOH HOH B . 
H 4 HOH 442 1142 917 HOH HOH B . 
H 4 HOH 443 1143 607 HOH HOH B . 
H 4 HOH 444 1144 549 HOH HOH B . 
H 4 HOH 445 1145 931 HOH HOH B . 
H 4 HOH 446 1146 947 HOH HOH B . 
H 4 HOH 447 1147 586 HOH HOH B . 
H 4 HOH 448 1148 369 HOH HOH B . 
H 4 HOH 449 1149 961 HOH HOH B . 
H 4 HOH 450 1150 614 HOH HOH B . 
H 4 HOH 451 1151 886 HOH HOH B . 
H 4 HOH 452 1152 592 HOH HOH B . 
H 4 HOH 453 1153 621 HOH HOH B . 
H 4 HOH 454 1154 484 HOH HOH B . 
H 4 HOH 455 1155 887 HOH HOH B . 
H 4 HOH 456 1156 790 HOH HOH B . 
H 4 HOH 457 1157 755 HOH HOH B . 
H 4 HOH 458 1158 844 HOH HOH B . 
H 4 HOH 459 1159 924 HOH HOH B . 
H 4 HOH 460 1160 834 HOH HOH B . 
H 4 HOH 461 1161 829 HOH HOH B . 
H 4 HOH 462 1162 703 HOH HOH B . 
H 4 HOH 463 1163 530 HOH HOH B . 
H 4 HOH 464 1164 877 HOH HOH B . 
H 4 HOH 465 1165 658 HOH HOH B . 
H 4 HOH 466 1166 387 HOH HOH B . 
H 4 HOH 467 1167 927 HOH HOH B . 
H 4 HOH 468 1168 608 HOH HOH B . 
H 4 HOH 469 1169 767 HOH HOH B . 
H 4 HOH 470 1170 943 HOH HOH B . 
H 4 HOH 471 1171 757 HOH HOH B . 
H 4 HOH 472 1172 231 HOH HOH B . 
H 4 HOH 473 1173 920 HOH HOH B . 
H 4 HOH 474 1174 269 HOH HOH B . 
H 4 HOH 475 1175 972 HOH HOH B . 
H 4 HOH 476 1176 930 HOH HOH B . 
H 4 HOH 477 1177 555 HOH HOH B . 
H 4 HOH 478 1178 971 HOH HOH B . 
H 4 HOH 479 1179 518 HOH HOH B . 
H 4 HOH 480 1180 926 HOH HOH B . 
H 4 HOH 481 1181 968 HOH HOH B . 
H 4 HOH 482 1182 349 HOH HOH B . 
H 4 HOH 483 1183 950 HOH HOH B . 
H 4 HOH 484 1184 649 HOH HOH B . 
H 4 HOH 485 1185 951 HOH HOH B . 
H 4 HOH 486 1186 952 HOH HOH B . 
H 4 HOH 487 1187 616 HOH HOH B . 
H 4 HOH 488 1188 583 HOH HOH B . 
H 4 HOH 489 1189 944 HOH HOH B . 
H 4 HOH 490 1190 799 HOH HOH B . 
H 4 HOH 491 1191 463 HOH HOH B . 
H 4 HOH 492 1192 916 HOH HOH B . 
H 4 HOH 493 1193 959 HOH HOH B . 
H 4 HOH 494 1194 969 HOH HOH B . 
H 4 HOH 495 1195 946 HOH HOH B . 
H 4 HOH 496 1196 973 HOH HOH B . 
H 4 HOH 497 1197 729 HOH HOH B . 
H 4 HOH 498 1198 948 HOH HOH B . 
H 4 HOH 499 1199 933 HOH HOH B . 
H 4 HOH 500 1200 642 HOH HOH B . 
H 4 HOH 501 1201 832 HOH HOH B . 
H 4 HOH 502 1202 303 HOH HOH B . 
H 4 HOH 503 1203 398 HOH HOH B . 
H 4 HOH 504 1204 855 HOH HOH B . 
H 4 HOH 505 1205 960 HOH HOH B . 
H 4 HOH 506 1206 970 HOH HOH B . 
H 4 HOH 507 1207 619 HOH HOH B . 
H 4 HOH 508 1208 897 HOH HOH B . 
H 4 HOH 509 1209 963 HOH HOH B . 
H 4 HOH 510 1210 534 HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0430 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   108.399 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9G8F 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     71.883 
_cell.length_a_esd                 ? 
_cell.length_b                     84.937 
_cell.length_b_esd                 ? 
_cell.length_c                     107.02 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9G8F 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9G8F 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.46 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          50.08 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2M Sodium acetate trihydrate 0.1M Sodium HEPES 7.525% w/v PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-08-18 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.03322 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, DESY BEAMLINE P11' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.03322 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   P11 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, DESY' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9G8F 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.84 
_reflns.d_resolution_low                               48.76 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     101754 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           96.8 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               0.98 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.184 
_reflns.pdbx_Rpim_I_all                                0.099 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.990 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.154 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
10.10 48.76 ? 17.8 ? ? ? ? 681  ? ? ? ? ? ? ? ? ? ? ? 6.5 1.02 ? ? 0.103 0.054 ? 1 ? 0.994 ? ? 98.9 ? 0.088 ? ? ? ? ? ? ? ? ? 
1.84  1.88  ? 4.0  ? ? ? ? 3118 ? ? ? ? ? ? ? ? ? ? ? 6.5 0.60 ? ? 0.735 0.394 ? 2 ? 0.919 ? ? 60.5 ? 0.618 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            -1.085 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.903 
_refine.aniso_B[2][2]                            -0.462 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.774 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               20.601 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.922 
_refine.correlation_coeff_Fo_to_Fc_free          0.881 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9G8F 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.844 
_refine.ls_d_res_low                             48.76 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     101375 
_refine.ls_number_reflns_R_free                  5064 
_refine.ls_number_reflns_R_work                  96311 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    96.338 
_refine.ls_percent_reflns_R_free                 4.995 
_refine.ls_R_factor_all                          0.212 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2593 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2095 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.160 
_refine.pdbx_overall_ESU_R_Free                  0.154 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             3.507 
_refine.overall_SU_ML                            0.109 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.844 
_refine_hist.d_res_low                        48.76 
_refine_hist.number_atoms_solvent             996 
_refine_hist.number_atoms_total               9440 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8420 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         24 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.014  0.012  8706  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 2.344  1.820  11850 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 7.961  5.000  1048  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 10.327 6.000  60    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.668 10.000 1358  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.831 10.000 430   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.164  0.200  1216  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.014  0.020  6978  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.212  0.200  4446  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.305  0.200  5808  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.203  0.200  1036  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.207  0.200  54    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.129  0.200  21    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.476  1.838  4198  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 3.197  3.295  5244  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.321  2.024  4508  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.385  3.619  6606  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 6.382  21.455 14228 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 0.077  0.050  17538 ? r_ncsr_local_group_1           ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.ncs_model_details 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.pdbx_ens_id 
'X-RAY DIFFRACTION' 1 ? ? 0.07711 ? 0.05008 1 'Local ncs' ? A ? ? ? 1 
'X-RAY DIFFRACTION' 2 ? ? 0.07711 ? 0.05008 2 'Local ncs' ? B ? ? ? 1 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.844 1.892 7736 . 290 5420 73.8108 . 0.221 . . 0.218 . . . . . 0.200 . 20 . 0.968 0.947 0.280 
'X-RAY DIFFRACTION' 1.892 1.943 7545 . 361 7147 99.5096 . 0.211 . . 0.207 . . . . . 0.190 . 20 . 0.971 0.945 0.282 
'X-RAY DIFFRACTION' 1.943 2.000 7307 . 381 6880 99.3705 . 0.213 . . 0.210 . . . . . 0.192 . 20 . 0.969 0.952 0.265 
'X-RAY DIFFRACTION' 2.000 2.061 7166 . 271 6835 99.1627 . 0.212 . . 0.210 . . . . . 0.194 . 20 . 0.969 0.951 0.271 
'X-RAY DIFFRACTION' 2.061 2.129 6880 . 320 6456 98.4884 . 0.199 . . 0.197 . . . . . 0.183 . 20 . 0.973 0.956 0.245 
'X-RAY DIFFRACTION' 2.129 2.203 6691 . 350 6232 98.3709 . 0.200 . . 0.197 . . . . . 0.184 . 20 . 0.973 0.955 0.256 
'X-RAY DIFFRACTION' 2.203 2.286 6478 . 348 5997 97.9469 . 0.211 . . 0.207 . . . . . 0.194 . 20 . 0.969 0.951 0.268 
'X-RAY DIFFRACTION' 2.286 2.379 6205 . 337 5699 97.2764 . 0.223 . . 0.219 . . . . . 0.205 . 20 . 0.967 0.946 0.287 
'X-RAY DIFFRACTION' 2.379 2.485 5983 . 278 5422 95.2699 . 0.229 . . 0.226 . . . . . 0.212 . 20 . 0.963 0.947 0.288 
'X-RAY DIFFRACTION' 2.485 2.606 5696 . 308 5340 99.1573 . 0.218 . . 0.215 . . . . . 0.209 . 20 . 0.970 0.944 0.285 
'X-RAY DIFFRACTION' 2.606 2.746 5447 . 280 5131 99.3391 . 0.212 . . 0.209 . . . . . 0.204 . 20 . 0.971 0.957 0.262 
'X-RAY DIFFRACTION' 2.746 2.912 5133 . 287 4791 98.9285 . 0.223 . . 0.219 . . . . . 0.219 . 20 . 0.968 0.948 0.287 
'X-RAY DIFFRACTION' 2.912 3.113 4846 . 229 4543 98.4730 . 0.222 . . 0.220 . . . . . 0.222 . 20 . 0.967 0.950 0.266 
'X-RAY DIFFRACTION' 3.113 3.361 4516 . 191 4257 98.4942 . 0.222 . . 0.219 . . . . . 0.224 . 20 . 0.966 0.955 0.271 
'X-RAY DIFFRACTION' 3.361 3.680 4140 . 218 3822 97.5845 . 0.217 . . 0.215 . . . . . 0.220 . 20 . 0.967 0.958 0.249 
'X-RAY DIFFRACTION' 3.680 4.111 3766 . 165 3440 95.7249 . 0.220 . . 0.218 . . . . . 0.231 . 20 . 0.966 0.953 0.256 
'X-RAY DIFFRACTION' 4.111 4.742 3359 . 153 2904 91.0092 . 0.195 . . 0.194 . . . . . 0.207 . 20 . 0.973 0.967 0.205 
'X-RAY DIFFRACTION' 4.742 5.794 2820 . 150 2649 99.2553 . 0.195 . . 0.193 . . . . . 0.208 . 20 . 0.973 0.966 0.224 
'X-RAY DIFFRACTION' 5.794 8.136 2224 . 89  2125 99.5504 . 0.196 . . 0.194 . . . . . 0.213 . 20 . 0.974 0.961 0.251 
'X-RAY DIFFRACTION' 8.136 48.76 1282 . 58  1221 99.7660 . 0.188 . . 0.188 . . . . . 0.214 . 20 . 0.977 0.975 0.189 
# 
loop_
_struct_ncs_dom.id 
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.details 
1 1 A 
2 1 B 
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
1 1 1 A TYR 32 . A ALA 556 . A TYR 24 A ALA 548 ? ? 
1 2 1 B TYR 32 . B ALA 556 . B TYR 24 B ALA 548 ? ? 
# 
_struct_ncs_ens.id        1 
_struct_ncs_ens.details   'Local NCS retraints between domains:       1       2' 
# 
_struct.entry_id                     9G8F 
_struct.title                        'Carotenoid cleavage oxygenase from Moesziomyces aphidis bound to orto vanillin' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9G8F 
_struct_keywords.text            'oxygenase, Moesziomyces aphidis, METAL BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'METAL BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 2 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    W3VHW6_MOEAP 
_struct_ref.pdbx_db_accession          W3VHW6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;APTATQEPVPVPVTSKAAPSHGYVHPTDILPSGWPTATDLSGGAQPRRFEGTIFDVMTRGTIPKELHGTFYRIMPDYAQP
PTYYKGGELNAPIDGDGTVAAFRFKDGKVDYRQRFVETDRFKVERRARKSMYGLYRNPYTHHPCVRQTVESTANTNVVMH
AGRFLAMKENGNAYEMDPHTLKTLGYNPFNLPSKTMTAHPKQCSVTGNLVGFGYEAKGLATKDVYYFEVDPSGKVVRDLW
LEAPWCAFIHDCALTPNYLVLMLWPFEANLERMKAGGHHWAYDYTKPITWITIPRGAKSKDEVKYWHWKNGMPIHTASGF
EDEQGRIIIDSSLVHGNAFPFFPPDSDEQKKKQEADGTPKAQFVRWTIDPRKDNNEQLPDPEVILDTPSEFPQIDNRFMG
VEYSSAFINVFVPDRSDGNKNVFQGLNGLAHYKRKEGTTEWYYAGDNCLIQEPVFSPRSKDAPEGDGFVLAIVDRLDLNR
SEVVVIDTRDFTKAVAAVQLPFAIRSGIHGQWIPGEVTPDFETKGLVDLPKEEHWAPLSQSPYDPDA
;
_struct_ref.pdbx_align_begin           2 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9G8F A 10 ? 556 ? W3VHW6 2 ? 548 ? 2 548 
2 1 9G8F B 10 ? 556 ? W3VHW6 2 ? 548 ? 2 548 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9G8F MET A 1 ? UNP W3VHW6 ? ? 'initiating methionine' -7 1  
1 9G8F TRP A 2 ? UNP W3VHW6 ? ? 'expression tag'        -6 2  
1 9G8F SER A 3 ? UNP W3VHW6 ? ? 'expression tag'        -5 3  
1 9G8F HIS A 4 ? UNP W3VHW6 ? ? 'expression tag'        -4 4  
1 9G8F PRO A 5 ? UNP W3VHW6 ? ? 'expression tag'        -3 5  
1 9G8F GLN A 6 ? UNP W3VHW6 ? ? 'expression tag'        -2 6  
1 9G8F PHE A 7 ? UNP W3VHW6 ? ? 'expression tag'        -1 7  
1 9G8F GLU A 8 ? UNP W3VHW6 ? ? 'expression tag'        0  8  
1 9G8F LYS A 9 ? UNP W3VHW6 ? ? 'expression tag'        1  9  
2 9G8F MET B 1 ? UNP W3VHW6 ? ? 'initiating methionine' -7 10 
2 9G8F TRP B 2 ? UNP W3VHW6 ? ? 'expression tag'        -6 11 
2 9G8F SER B 3 ? UNP W3VHW6 ? ? 'expression tag'        -5 12 
2 9G8F HIS B 4 ? UNP W3VHW6 ? ? 'expression tag'        -4 13 
2 9G8F PRO B 5 ? UNP W3VHW6 ? ? 'expression tag'        -3 14 
2 9G8F GLN B 6 ? UNP W3VHW6 ? ? 'expression tag'        -2 15 
2 9G8F PHE B 7 ? UNP W3VHW6 ? ? 'expression tag'        -1 16 
2 9G8F GLU B 8 ? UNP W3VHW6 ? ? 'expression tag'        0  17 
2 9G8F LYS B 9 ? UNP W3VHW6 ? ? 'expression tag'        1  18 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,D,G 
2 1 B,E,F,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'light scattering' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 HIS A 34  ? LEU A 39  ? HIS A 26  LEU A 31  5 ? 6  
HELX_P HELX_P2  AA2 TYR A 93  ? GLU A 97  ? TYR A 85  GLU A 89  5 ? 5  
HELX_P HELX_P3  AA3 THR A 127 ? ARG A 137 ? THR A 119 ARG A 129 1 ? 11 
HELX_P HELX_P4  AA4 ASN A 146 ? HIS A 150 ? ASN A 138 HIS A 142 5 ? 5  
HELX_P HELX_P5  AA5 HIS A 151 ? ARG A 155 ? HIS A 143 ARG A 147 5 ? 5  
HELX_P HELX_P6  AA6 ASN A 278 ? ALA A 284 ? ASN A 270 ALA A 276 1 ? 7  
HELX_P HELX_P7  AA7 SER A 308 ? VAL A 312 ? SER A 300 VAL A 304 5 ? 5  
HELX_P HELX_P8  AA8 SER A 355 ? GLY A 366 ? SER A 347 GLY A 358 1 ? 12 
HELX_P HELX_P9  AA9 ASP A 404 ? MET A 408 ? ASP A 396 MET A 400 5 ? 5  
HELX_P HELX_P10 AB1 ARG A 498 ? PHE A 500 ? ARG A 490 PHE A 492 5 ? 3  
HELX_P HELX_P11 AB2 GLU A 525 ? THR A 527 ? GLU A 517 THR A 519 5 ? 3  
HELX_P HELX_P12 AB3 PRO A 546 ? SER A 550 ? PRO A 538 SER A 542 5 ? 5  
HELX_P HELX_P13 AB4 HIS B 34  ? LEU B 39  ? HIS B 26  LEU B 31  5 ? 6  
HELX_P HELX_P14 AB5 TYR B 93  ? GLU B 97  ? TYR B 85  GLU B 89  5 ? 5  
HELX_P HELX_P15 AB6 THR B 127 ? ARG B 137 ? THR B 119 ARG B 129 1 ? 11 
HELX_P HELX_P16 AB7 ASN B 146 ? HIS B 150 ? ASN B 138 HIS B 142 5 ? 5  
HELX_P HELX_P17 AB8 HIS B 151 ? ARG B 155 ? HIS B 143 ARG B 147 5 ? 5  
HELX_P HELX_P18 AB9 ASN B 278 ? ALA B 284 ? ASN B 270 ALA B 276 1 ? 7  
HELX_P HELX_P19 AC1 SER B 308 ? VAL B 312 ? SER B 300 VAL B 304 5 ? 5  
HELX_P HELX_P20 AC2 SER B 355 ? GLY B 366 ? SER B 347 GLY B 358 1 ? 12 
HELX_P HELX_P21 AC3 ASN B 405 ? MET B 408 ? ASN B 397 MET B 400 5 ? 4  
HELX_P HELX_P22 AC4 ASP B 486 ? ASN B 488 ? ASP B 478 ASN B 480 5 ? 3  
HELX_P HELX_P23 AC5 ARG B 498 ? PHE B 500 ? ARG B 490 PHE B 492 5 ? 3  
HELX_P HELX_P24 AC6 GLU B 525 ? THR B 527 ? GLU B 517 THR B 519 5 ? 3  
HELX_P HELX_P25 AC7 PRO B 546 ? SER B 550 ? PRO B 538 SER B 542 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A HIS 208 NE2 ? ? ? 1_555 D FE2 . FE ? ? A HIS 200 A FE2 602 1_555 ? ? ? ? ? ? ? 2.166 ? ? 
metalc2  metalc ? ? A HIS 259 NE2 ? ? ? 1_555 D FE2 . FE ? ? A HIS 251 A FE2 602 1_555 ? ? ? ? ? ? ? 2.151 ? ? 
metalc3  metalc ? ? A HIS 324 NE2 ? ? ? 1_555 D FE2 . FE ? ? A HIS 316 A FE2 602 1_555 ? ? ? ? ? ? ? 2.101 ? ? 
metalc4  metalc ? ? A HIS 518 NE2 ? ? ? 1_555 D FE2 . FE ? ? A HIS 510 A FE2 602 1_555 ? ? ? ? ? ? ? 2.165 ? ? 
metalc5  metalc ? ? D FE2 .   FE  ? ? ? 1_555 G HOH . O  ? ? A FE2 602 A HOH 884 1_555 ? ? ? ? ? ? ? 2.083 ? ? 
metalc6  metalc ? ? B HIS 208 NE2 ? ? ? 1_555 F FE2 . FE ? ? B HIS 200 B FE2 602 1_555 ? ? ? ? ? ? ? 2.155 ? ? 
metalc7  metalc ? ? B HIS 259 NE2 ? ? ? 1_555 F FE2 . FE ? ? B HIS 251 B FE2 602 1_555 ? ? ? ? ? ? ? 2.082 ? ? 
metalc8  metalc ? ? B HIS 324 NE2 ? ? ? 1_555 F FE2 . FE ? ? B HIS 316 B FE2 602 1_555 ? ? ? ? ? ? ? 2.192 ? ? 
metalc9  metalc ? ? B HIS 518 NE2 ? ? ? 1_555 F FE2 . FE ? ? B HIS 510 B FE2 602 1_555 ? ? ? ? ? ? ? 2.162 ? ? 
metalc10 metalc ? ? F FE2 .   FE  ? ? ? 1_555 H HOH . O  ? ? B FE2 602 B HOH 999 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 259 ? A HIS 251 ? 1_555 90.4  ? 
2  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 324 ? A HIS 316 ? 1_555 100.1 ? 
3  NE2 ? A HIS 259 ? A HIS 251 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 324 ? A HIS 316 ? 1_555 94.1  ? 
4  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 88.5  ? 
5  NE2 ? A HIS 259 ? A HIS 251 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 176.5 ? 
6  NE2 ? A HIS 324 ? A HIS 316 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 89.3  ? 
7  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? G HOH .   ? A HOH 884 ? 1_555 129.7 ? 
8  NE2 ? A HIS 259 ? A HIS 251 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? G HOH .   ? A HOH 884 ? 1_555 88.6  ? 
9  NE2 ? A HIS 324 ? A HIS 316 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? G HOH .   ? A HOH 884 ? 1_555 130.2 ? 
10 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? G HOH .   ? A HOH 884 ? 1_555 89.7  ? 
11 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 92.4  ? 
12 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 101.5 ? 
13 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 93.6  ? 
14 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 89.3  ? 
15 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 178.1 ? 
16 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 86.8  ? 
17 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? H HOH .   ? B HOH 999 ? 1_555 132.8 ? 
18 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? H HOH .   ? B HOH 999 ? 1_555 91.5  ? 
19 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? H HOH .   ? B HOH 999 ? 1_555 125.2 ? 
20 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? H HOH .   ? B HOH 999 ? 1_555 86.7  ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 10 ? 
AA2 ? 5  ? 
AA3 ? 5  ? 
AA4 ? 4  ? 
AA5 ? 4  ? 
AA6 ? 3  ? 
AA7 ? 4  ? 
AA8 ? 4  ? 
AA9 ? 4  ? 
AB1 ? 5  ? 
AB2 ? 5  ? 
AB3 ? 4  ? 
AB4 ? 4  ? 
AB5 ? 3  ? 
AB6 ? 4  ? 
AB7 ? 4  ? 
AB8 ? 4  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? anti-parallel 
AA1 2 3  ? anti-parallel 
AA1 3 4  ? anti-parallel 
AA1 4 5  ? anti-parallel 
AA1 5 6  ? anti-parallel 
AA1 6 7  ? anti-parallel 
AA1 7 8  ? anti-parallel 
AA1 8 9  ? anti-parallel 
AA1 9 10 ? anti-parallel 
AA2 1 2  ? anti-parallel 
AA2 2 3  ? anti-parallel 
AA2 3 4  ? anti-parallel 
AA2 4 5  ? anti-parallel 
AA3 1 2  ? anti-parallel 
AA3 2 3  ? anti-parallel 
AA3 3 4  ? anti-parallel 
AA3 4 5  ? anti-parallel 
AA4 1 2  ? anti-parallel 
AA4 2 3  ? anti-parallel 
AA4 3 4  ? anti-parallel 
AA5 1 2  ? anti-parallel 
AA5 2 3  ? anti-parallel 
AA5 3 4  ? anti-parallel 
AA6 1 2  ? anti-parallel 
AA6 2 3  ? anti-parallel 
AA7 1 2  ? anti-parallel 
AA7 2 3  ? anti-parallel 
AA7 3 4  ? anti-parallel 
AA8 1 2  ? anti-parallel 
AA8 2 3  ? anti-parallel 
AA8 3 4  ? anti-parallel 
AA9 1 2  ? anti-parallel 
AA9 2 3  ? anti-parallel 
AA9 3 4  ? anti-parallel 
AB1 1 2  ? anti-parallel 
AB1 2 3  ? anti-parallel 
AB1 3 4  ? anti-parallel 
AB1 4 5  ? anti-parallel 
AB2 1 2  ? anti-parallel 
AB2 2 3  ? anti-parallel 
AB2 3 4  ? anti-parallel 
AB2 4 5  ? anti-parallel 
AB3 1 2  ? anti-parallel 
AB3 2 3  ? anti-parallel 
AB3 3 4  ? anti-parallel 
AB4 1 2  ? anti-parallel 
AB4 2 3  ? anti-parallel 
AB4 3 4  ? anti-parallel 
AB5 1 2  ? anti-parallel 
AB5 2 3  ? anti-parallel 
AB6 1 2  ? anti-parallel 
AB6 2 3  ? anti-parallel 
AB6 3 4  ? anti-parallel 
AB7 1 2  ? anti-parallel 
AB7 2 3  ? anti-parallel 
AB7 3 4  ? anti-parallel 
AB8 1 2  ? anti-parallel 
AB8 2 3  ? anti-parallel 
AB8 3 4  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  GLY A 519 ? PRO A 523 ? GLY A 511 PRO A 515 
AA1 2  GLY A 77  ? PRO A 84  ? GLY A 69  PRO A 76  
AA1 3  GLY A 106 ? LYS A 114 ? GLY A 98  LYS A 106 
AA1 4  LYS A 117 ? PHE A 124 ? LYS A 109 PHE A 116 
AA1 5  GLU A 59  ? ILE A 62  ? GLU A 51  ILE A 54  
AA1 6  GLU B 59  ? ILE B 62  ? GLU B 51  ILE B 54  
AA1 7  LYS B 117 ? PHE B 124 ? LYS B 109 PHE B 116 
AA1 8  GLY B 106 ? LYS B 114 ? GLY B 98  LYS B 106 
AA1 9  GLY B 77  ? PRO B 84  ? GLY B 69  PRO B 76  
AA1 10 GLY B 519 ? PRO B 523 ? GLY B 511 PRO B 515 
AA2 1  THR A 67  ? GLY A 69  ? THR A 59  GLY A 61  
AA2 2  ALA A 503 ? GLN A 508 ? ALA A 495 GLN A 500 
AA2 3  ARG A 489 ? ASP A 496 ? ARG A 481 ASP A 488 
AA2 4  GLY A 476 ? ARG A 484 ? GLY A 468 ARG A 476 
AA2 5  CYS A 457 ? ILE A 459 ? CYS A 449 ILE A 451 
AA3 1  THR A 67  ? GLY A 69  ? THR A 59  GLY A 61  
AA3 2  ALA A 503 ? GLN A 508 ? ALA A 495 GLN A 500 
AA3 3  ARG A 489 ? ASP A 496 ? ARG A 481 ASP A 488 
AA3 4  GLY A 476 ? ARG A 484 ? GLY A 468 ARG A 476 
AA3 5  VAL A 463 ? PRO A 466 ? VAL A 455 PRO A 458 
AA4 1  ASN A 165 ? HIS A 169 ? ASN A 157 HIS A 161 
AA4 2  ARG A 172 ? MET A 176 ? ARG A 164 MET A 168 
AA4 3  TYR A 183 ? MET A 185 ? TYR A 175 MET A 177 
AA4 4  THR A 192 ? TYR A 195 ? THR A 184 TYR A 187 
AA5 1  LYS A 210 ? GLN A 211 ? LYS A 202 GLN A 203 
AA5 2  LEU A 218 ? TYR A 223 ? LEU A 210 TYR A 215 
AA5 3  ASP A 232 ? VAL A 238 ? ASP A 224 VAL A 230 
AA5 4  VAL A 244 ? GLU A 251 ? VAL A 236 GLU A 243 
AA6 1  ALA A 256 ? LEU A 263 ? ALA A 248 LEU A 255 
AA6 2  TYR A 267 ? ALA A 277 ? TYR A 259 ALA A 269 
AA6 3  TRP A 289 ? TYR A 291 ? TRP A 281 TYR A 283 
AA7 1  ALA A 256 ? LEU A 263 ? ALA A 248 LEU A 255 
AA7 2  TYR A 267 ? ALA A 277 ? TYR A 259 ALA A 269 
AA7 3  THR A 298 ? PRO A 303 ? THR A 290 PRO A 295 
AA7 4  LYS A 313 ? HIS A 316 ? LYS A 305 HIS A 308 
AA8 1  THR A 325 ? GLU A 330 ? THR A 317 GLU A 322 
AA8 2  ILE A 336 ? VAL A 343 ? ILE A 328 VAL A 335 
AA8 3  ALA A 370 ? ILE A 377 ? ALA A 362 ILE A 369 
AA8 4  GLU A 391 ? LEU A 394 ? GLU A 383 LEU A 386 
AA9 1  SER A 398 ? GLN A 402 ? SER A 390 GLN A 394 
AA9 2  SER A 414 ? VAL A 419 ? SER A 406 VAL A 411 
AA9 3  GLY A 437 ? LYS A 442 ? GLY A 429 LYS A 434 
AA9 4  THR A 447 ? TYR A 452 ? THR A 439 TYR A 444 
AB1 1  THR B 67  ? GLY B 69  ? THR B 59  GLY B 61  
AB1 2  ALA B 503 ? GLN B 508 ? ALA B 495 GLN B 500 
AB1 3  ARG B 489 ? ASP B 496 ? ARG B 481 ASP B 488 
AB1 4  GLY B 476 ? ARG B 484 ? GLY B 468 ARG B 476 
AB1 5  CYS B 457 ? ILE B 459 ? CYS B 449 ILE B 451 
AB2 1  THR B 67  ? GLY B 69  ? THR B 59  GLY B 61  
AB2 2  ALA B 503 ? GLN B 508 ? ALA B 495 GLN B 500 
AB2 3  ARG B 489 ? ASP B 496 ? ARG B 481 ASP B 488 
AB2 4  GLY B 476 ? ARG B 484 ? GLY B 468 ARG B 476 
AB2 5  VAL B 463 ? PRO B 466 ? VAL B 455 PRO B 458 
AB3 1  ASN B 165 ? HIS B 169 ? ASN B 157 HIS B 161 
AB3 2  ARG B 172 ? MET B 176 ? ARG B 164 MET B 168 
AB3 3  TYR B 183 ? MET B 185 ? TYR B 175 MET B 177 
AB3 4  THR B 192 ? TYR B 195 ? THR B 184 TYR B 187 
AB4 1  LYS B 210 ? GLN B 211 ? LYS B 202 GLN B 203 
AB4 2  LEU B 218 ? TYR B 223 ? LEU B 210 TYR B 215 
AB4 3  ASP B 232 ? VAL B 238 ? ASP B 224 VAL B 230 
AB4 4  VAL B 244 ? GLU B 251 ? VAL B 236 GLU B 243 
AB5 1  ALA B 256 ? LEU B 263 ? ALA B 248 LEU B 255 
AB5 2  TYR B 267 ? ALA B 277 ? TYR B 259 ALA B 269 
AB5 3  TRP B 289 ? TYR B 291 ? TRP B 281 TYR B 283 
AB6 1  ALA B 256 ? LEU B 263 ? ALA B 248 LEU B 255 
AB6 2  TYR B 267 ? ALA B 277 ? TYR B 259 ALA B 269 
AB6 3  THR B 298 ? PRO B 303 ? THR B 290 PRO B 295 
AB6 4  LYS B 313 ? HIS B 316 ? LYS B 305 HIS B 308 
AB7 1  THR B 325 ? GLU B 330 ? THR B 317 GLU B 322 
AB7 2  ILE B 336 ? VAL B 343 ? ILE B 328 VAL B 335 
AB7 3  ALA B 370 ? ILE B 377 ? ALA B 362 ILE B 369 
AB7 4  GLU B 391 ? LEU B 394 ? GLU B 383 LEU B 386 
AB8 1  SER B 398 ? ILE B 403 ? SER B 390 ILE B 395 
AB8 2  SER B 414 ? VAL B 419 ? SER B 406 VAL B 411 
AB8 3  GLY B 437 ? LYS B 442 ? GLY B 429 LYS B 434 
AB8 4  THR B 447 ? TYR B 452 ? THR B 439 TYR B 444 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  O ILE A 522 ? O ILE A 514 N THR A 78  ? N THR A 70  
AA1 2 3  N ARG A 81  ? N ARG A 73  O ALA A 109 ? O ALA A 101 
AA1 3 4  N ALA A 110 ? N ALA A 102 O ARG A 121 ? O ARG A 113 
AA1 4 5  O GLN A 122 ? O GLN A 114 N GLY A 60  ? N GLY A 52  
AA1 5 6  N THR A 61  ? N THR A 53  O GLU B 59  ? O GLU B 51  
AA1 6 7  N GLY B 60  ? N GLY B 52  O GLN B 122 ? O GLN B 114 
AA1 7 8  O ARG B 121 ? O ARG B 113 N ALA B 110 ? N ALA B 102 
AA1 8 9  O ALA B 109 ? O ALA B 101 N ARG B 81  ? N ARG B 73  
AA1 9 10 N THR B 78  ? N THR B 70  O ILE B 522 ? O ILE B 514 
AA2 1 2  N ARG A 68  ? N ARG A 60  O ALA A 506 ? O ALA A 498 
AA2 2 3  O VAL A 507 ? O VAL A 499 N VAL A 492 ? N VAL A 484 
AA2 3 4  O GLU A 491 ? O GLU A 483 N VAL A 482 ? N VAL A 474 
AA2 4 5  O ASP A 483 ? O ASP A 475 N LEU A 458 ? N LEU A 450 
AA3 1 2  N ARG A 68  ? N ARG A 60  O ALA A 506 ? O ALA A 498 
AA3 2 3  O VAL A 507 ? O VAL A 499 N VAL A 492 ? N VAL A 484 
AA3 3 4  O GLU A 491 ? O GLU A 483 N VAL A 482 ? N VAL A 474 
AA3 4 5  O PHE A 477 ? O PHE A 469 N SER A 465 ? N SER A 457 
AA4 1 2  N VAL A 167 ? N VAL A 159 O LEU A 174 ? O LEU A 166 
AA4 2 3  N ALA A 175 ? N ALA A 167 O TYR A 183 ? O TYR A 175 
AA4 3 4  N GLU A 184 ? N GLU A 176 O LEU A 193 ? O LEU A 185 
AA5 1 2  N LYS A 210 ? N LYS A 202 O VAL A 219 ? O VAL A 211 
AA5 2 3  N LEU A 218 ? N LEU A 210 O VAL A 238 ? O VAL A 230 
AA5 3 4  N TYR A 235 ? N TYR A 227 O LEU A 248 ? O LEU A 240 
AA6 1 2  N ALA A 262 ? N ALA A 254 O VAL A 269 ? O VAL A 261 
AA6 2 3  N GLU A 276 ? N GLU A 268 O ALA A 290 ? O ALA A 282 
AA7 1 2  N ALA A 262 ? N ALA A 254 O VAL A 269 ? O VAL A 261 
AA7 2 3  N LEU A 272 ? N LEU A 264 O THR A 298 ? O THR A 290 
AA7 3 4  N THR A 301 ? N THR A 293 O LYS A 313 ? O LYS A 305 
AA8 1 2  N ALA A 326 ? N ALA A 318 O ASP A 339 ? O ASP A 331 
AA8 2 3  N ILE A 338 ? N ILE A 330 O TRP A 375 ? O TRP A 367 
AA8 3 4  N ARG A 374 ? N ARG A 366 O GLU A 391 ? O GLU A 383 
AA9 1 2  N GLN A 402 ? N GLN A 394 O PHE A 416 ? O PHE A 408 
AA9 2 3  N ALA A 415 ? N ALA A 407 O TYR A 441 ? O TYR A 433 
AA9 3 4  N LEU A 438 ? N LEU A 430 O TYR A 451 ? O TYR A 443 
AB1 1 2  N ARG B 68  ? N ARG B 60  O ALA B 506 ? O ALA B 498 
AB1 2 3  O VAL B 507 ? O VAL B 499 N VAL B 492 ? N VAL B 484 
AB1 3 4  O GLU B 491 ? O GLU B 483 N VAL B 482 ? N VAL B 474 
AB1 4 5  O ASP B 483 ? O ASP B 475 N LEU B 458 ? N LEU B 450 
AB2 1 2  N ARG B 68  ? N ARG B 60  O ALA B 506 ? O ALA B 498 
AB2 2 3  O VAL B 507 ? O VAL B 499 N VAL B 492 ? N VAL B 484 
AB2 3 4  O GLU B 491 ? O GLU B 483 N VAL B 482 ? N VAL B 474 
AB2 4 5  O PHE B 477 ? O PHE B 469 N SER B 465 ? N SER B 457 
AB3 1 2  N HIS B 169 ? N HIS B 161 O ARG B 172 ? O ARG B 164 
AB3 2 3  N PHE B 173 ? N PHE B 165 O MET B 185 ? O MET B 177 
AB3 3 4  N GLU B 184 ? N GLU B 176 O LEU B 193 ? O LEU B 185 
AB4 1 2  N LYS B 210 ? N LYS B 202 O VAL B 219 ? O VAL B 211 
AB4 2 3  N LEU B 218 ? N LEU B 210 O VAL B 238 ? O VAL B 230 
AB4 3 4  N TYR B 235 ? N TYR B 227 O LEU B 248 ? O LEU B 240 
AB5 1 2  N ALA B 262 ? N ALA B 254 O VAL B 269 ? O VAL B 261 
AB5 2 3  N GLU B 276 ? N GLU B 268 O ALA B 290 ? O ALA B 282 
AB6 1 2  N ALA B 262 ? N ALA B 254 O VAL B 269 ? O VAL B 261 
AB6 2 3  N LEU B 272 ? N LEU B 264 O THR B 298 ? O THR B 290 
AB6 3 4  N TRP B 299 ? N TRP B 291 O TRP B 315 ? O TRP B 307 
AB7 1 2  N ALA B 326 ? N ALA B 318 O ASP B 339 ? O ASP B 331 
AB7 2 3  N ILE B 338 ? N ILE B 330 O TRP B 375 ? O TRP B 367 
AB7 3 4  N ARG B 374 ? N ARG B 366 O GLU B 391 ? O GLU B 383 
AB8 1 2  N GLN B 402 ? N GLN B 394 O PHE B 416 ? O PHE B 408 
AB8 2 3  N VAL B 419 ? N VAL B 411 O GLY B 437 ? O GLY B 429 
AB8 3 4  N LEU B 438 ? N LEU B 430 O TYR B 451 ? O TYR B 443 
# 
_pdbx_entry_details.entry_id                   9G8F 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 O   B HOH 718  ? ? O B HOH 721  ? ? 1.08 
2  1 C5  A V9L 601  ? ? O A HOH 708  ? ? 1.62 
3  1 C5  B V9L 601  ? ? O B HOH 716  ? ? 1.71 
4  1 O   A HOH 724  ? ? O A HOH 777  ? ? 1.74 
5  1 NE2 B GLN 500  ? ? O B HOH 701  ? ? 1.78 
6  1 O   A GLU 176  ? ? O A HOH 701  ? ? 1.80 
7  1 N   A THR 141  ? ? O A HOH 702  ? ? 1.93 
8  1 O   B ASP 396  ? ? O B HOH 702  ? ? 1.98 
9  1 N   B GLY 419  ? ? O B HOH 703  ? ? 1.98 
10 1 O   B ASP 77   ? ? O B HOH 704  ? ? 1.99 
11 1 O   B HOH 713  ? ? O B HOH 1152 ? ? 2.04 
12 1 NE  A ARG 147  ? ? O A HOH 703  ? ? 2.09 
13 1 O   B HOH 918  ? ? O B HOH 945  ? ? 2.09 
14 1 O   A HIS 142  ? ? O A HOH 703  ? ? 2.11 
15 1 N   A GLY 419  ? ? O A HOH 704  ? ? 2.11 
16 1 O   A HOH 1020 ? ? O A HOH 1025 ? ? 2.13 
17 1 O   A HOH 990  ? ? O A HOH 1126 ? ? 2.13 
18 1 CE  A MET 313  ? ? O A HOH 757  ? ? 2.14 
19 1 C   A GLU 176  ? ? O A HOH 701  ? ? 2.15 
20 1 O   A TYR 187  ? ? O A HOH 705  ? ? 2.16 
21 1 O   A ASN 138  ? ? O A HOH 702  ? ? 2.17 
22 1 O   A HOH 706  ? ? O A HOH 947  ? ? 2.17 
23 1 O   A HOH 953  ? ? O A HOH 1025 ? ? 2.18 
24 1 OE1 A GLN 46   ? ? O B HOH 701  ? ? 2.19 
25 1 OD1 A ASN 138  ? ? O A HOH 702  ? ? 2.19 
26 1 CB  A LEU 185  ? ? O A HOH 701  ? ? 2.19 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    HOH 
_pdbx_validate_symm_contact.auth_seq_id_1     775 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O 
_pdbx_validate_symm_contact.auth_asym_id_2    B 
_pdbx_validate_symm_contact.auth_comp_id_2    HOH 
_pdbx_validate_symm_contact.auth_seq_id_2     705 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   1_455 
_pdbx_validate_symm_contact.dist              2.07 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CD 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_1             118 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            OE2 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_2             118 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.184 
_pdbx_validate_rmsd_bond.bond_target_value         1.252 
_pdbx_validate_rmsd_bond.bond_deviation            -0.068 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.011 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 NE A ARG 49  ? ? CZ A ARG 49  ? ? NH1 A ARG 49  ? ? 123.73 120.30 3.43   0.50 N 
2  1 CG A ARG 73  ? ? CD A ARG 73  ? ? NE  A ARG 73  ? ? 95.24  111.80 -16.56 2.10 N 
3  1 CD A LYS 106 ? ? CE A LYS 106 ? ? NZ  A LYS 106 ? ? 96.74  111.70 -14.96 2.30 N 
4  1 CB A LYS 109 ? ? CG A LYS 109 ? ? CD  A LYS 109 ? ? 133.95 111.60 22.35  2.60 N 
5  1 CG A GLU 118 ? ? CD A GLU 118 ? ? OE1 A GLU 118 ? ? 130.64 118.30 12.34  2.00 N 
6  1 NE A ARG 126 ? ? CZ A ARG 126 ? ? NH1 A ARG 126 ? ? 115.93 120.30 -4.37  0.50 N 
7  1 NE A ARG 137 ? ? CZ A ARG 137 ? ? NH2 A ARG 137 ? ? 117.28 120.30 -3.02  0.50 N 
8  1 CG A ARG 147 ? ? CD A ARG 147 ? ? NE  A ARG 147 ? ? 95.39  111.80 -16.41 2.10 N 
9  1 NE A ARG 164 ? ? CZ A ARG 164 ? ? NH1 A ARG 164 ? ? 126.42 120.30 6.12   0.50 N 
10 1 NE A ARG 164 ? ? CZ A ARG 164 ? ? NH2 A ARG 164 ? ? 114.85 120.30 -5.45  0.50 N 
11 1 CB A LEU 192 ? ? CG A LEU 192 ? ? CD1 A LEU 192 ? ? 99.46  111.00 -11.54 1.70 N 
12 1 CB A HIS 251 ? ? CG A HIS 251 ? ? CD2 A HIS 251 ? ? 139.94 131.40 8.54   1.20 N 
13 1 NE A ARG 296 ? ? CZ A ARG 296 ? ? NH1 A ARG 296 ? ? 116.90 120.30 -3.40  0.50 N 
14 1 NE A ARG 366 ? ? CZ A ARG 366 ? ? NH2 A ARG 366 ? ? 116.41 120.30 -3.89  0.50 N 
15 1 CB A ASP 418 ? ? CA A ASP 418 ? ? C   A ASP 418 ? ? 124.97 110.40 14.57  2.00 N 
16 1 CB B LYS 109 ? ? CG B LYS 109 ? ? CD  B LYS 109 ? ? 129.20 111.60 17.60  2.60 N 
17 1 CG B ARG 147 ? ? CD B ARG 147 ? ? NE  B ARG 147 ? ? 95.56  111.80 -16.24 2.10 N 
18 1 NE B ARG 164 ? ? CZ B ARG 164 ? ? NH2 B ARG 164 ? ? 116.46 120.30 -3.84  0.50 N 
19 1 CB B LEU 192 ? ? CG B LEU 192 ? ? CD1 B LEU 192 ? ? 99.41  111.00 -11.59 1.70 N 
20 1 N  B LEU 220 ? ? CA B LEU 220 ? ? CB  B LEU 220 ? ? 95.23  110.40 -15.17 2.00 N 
21 1 CB B HIS 251 ? ? CG B HIS 251 ? ? CD2 B HIS 251 ? ? 138.67 131.40 7.27   1.20 N 
22 1 NE B ARG 366 ? ? CZ B ARG 366 ? ? NH1 B ARG 366 ? ? 123.47 120.30 3.17   0.50 N 
23 1 CB B ASP 418 ? ? CA B ASP 418 ? ? C   B ASP 418 ? ? 124.92 110.40 14.52  2.00 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 48  ? ? -117.64 -74.92  
2  1 ASP A 77  ? ? -158.07 78.73   
3  1 LEU A 182 ? ? 57.95   19.22   
4  1 ILE A 250 ? ? -102.09 79.89   
5  1 TRP A 309 ? ? -121.56 -105.56 
6  1 ALA A 318 ? ? -78.51  -75.29  
7  1 PHE A 340 ? ? -114.04 73.18   
8  1 PHE A 343 ? ? -107.66 73.79   
9  1 ASP A 387 ? ? -96.01  59.69   
10 1 PHE A 392 ? ? 32.74   66.99   
11 1 ASP A 415 ? ? 74.30   -0.07   
12 1 PRO A 464 ? ? -49.73  160.68  
13 1 ILE A 509 ? ? -104.06 -95.39  
14 1 ARG B 48  ? ? -113.36 -74.61  
15 1 ASP B 77  ? ? -155.91 71.22   
16 1 TYR B 78  ? ? -32.46  120.56  
17 1 LEU B 182 ? ? 58.77   17.79   
18 1 TRP B 309 ? ? -123.66 -109.83 
19 1 ALA B 318 ? ? -77.65  -74.10  
20 1 PHE B 340 ? ? -112.12 73.20   
21 1 PHE B 343 ? ? -109.95 76.30   
22 1 ASP B 387 ? ? -93.72  52.41   
23 1 PHE B 392 ? ? 38.12   59.69   
24 1 PRO B 464 ? ? -49.53  154.52  
25 1 ILE B 509 ? ? -108.40 -95.23  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG A 73  ? ? 0.075 'SIDE CHAIN' 
2  1 ARG A 129 ? ? 0.076 'SIDE CHAIN' 
3  1 ARG A 366 ? ? 0.081 'SIDE CHAIN' 
4  1 ARG A 459 ? ? 0.076 'SIDE CHAIN' 
5  1 ARG B 73  ? ? 0.120 'SIDE CHAIN' 
6  1 ARG B 127 ? ? 0.104 'SIDE CHAIN' 
7  1 ARG B 129 ? ? 0.079 'SIDE CHAIN' 
8  1 ARG B 147 ? ? 0.123 'SIDE CHAIN' 
9  1 ARG B 327 ? ? 0.094 'SIDE CHAIN' 
10 1 ARG B 366 ? ? 0.107 'SIDE CHAIN' 
11 1 ARG B 459 ? ? 0.078 'SIDE CHAIN' 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 1185 ? 5.90 . 
2 1 O ? A HOH 1186 ? 7.38 . 
3 1 O ? B HOH 1210 ? 6.49 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET -7 ? A MET 1  
2  1 Y 1 A TRP -6 ? A TRP 2  
3  1 Y 1 A SER -5 ? A SER 3  
4  1 Y 1 A HIS -4 ? A HIS 4  
5  1 Y 1 A PRO -3 ? A PRO 5  
6  1 Y 1 A GLN -2 ? A GLN 6  
7  1 Y 1 A PHE -1 ? A PHE 7  
8  1 Y 1 A GLU 0  ? A GLU 8  
9  1 Y 1 A LYS 1  ? A LYS 9  
10 1 Y 1 A ALA 2  ? A ALA 10 
11 1 Y 1 A PRO 3  ? A PRO 11 
12 1 Y 1 A THR 4  ? A THR 12 
13 1 Y 1 A ALA 5  ? A ALA 13 
14 1 Y 1 A THR 6  ? A THR 14 
15 1 Y 1 A GLN 7  ? A GLN 15 
16 1 Y 1 A GLU 8  ? A GLU 16 
17 1 Y 1 A PRO 9  ? A PRO 17 
18 1 Y 1 A VAL 10 ? A VAL 18 
19 1 Y 1 A PRO 11 ? A PRO 19 
20 1 Y 1 A VAL 12 ? A VAL 20 
21 1 Y 1 A PRO 13 ? A PRO 21 
22 1 Y 1 A VAL 14 ? A VAL 22 
23 1 Y 1 A THR 15 ? A THR 23 
24 1 Y 1 A SER 16 ? A SER 24 
25 1 Y 1 A LYS 17 ? A LYS 25 
26 1 Y 1 A ALA 18 ? A ALA 26 
27 1 Y 1 A ALA 19 ? A ALA 27 
28 1 Y 1 A PRO 20 ? A PRO 28 
29 1 Y 1 A SER 21 ? A SER 29 
30 1 Y 1 A HIS 22 ? A HIS 30 
31 1 Y 1 A GLY 23 ? A GLY 31 
32 1 Y 1 B MET -7 ? B MET 1  
33 1 Y 1 B TRP -6 ? B TRP 2  
34 1 Y 1 B SER -5 ? B SER 3  
35 1 Y 1 B HIS -4 ? B HIS 4  
36 1 Y 1 B PRO -3 ? B PRO 5  
37 1 Y 1 B GLN -2 ? B GLN 6  
38 1 Y 1 B PHE -1 ? B PHE 7  
39 1 Y 1 B GLU 0  ? B GLU 8  
40 1 Y 1 B LYS 1  ? B LYS 9  
41 1 Y 1 B ALA 2  ? B ALA 10 
42 1 Y 1 B PRO 3  ? B PRO 11 
43 1 Y 1 B THR 4  ? B THR 12 
44 1 Y 1 B ALA 5  ? B ALA 13 
45 1 Y 1 B THR 6  ? B THR 14 
46 1 Y 1 B GLN 7  ? B GLN 15 
47 1 Y 1 B GLU 8  ? B GLU 16 
48 1 Y 1 B PRO 9  ? B PRO 17 
49 1 Y 1 B VAL 10 ? B VAL 18 
50 1 Y 1 B PRO 11 ? B PRO 19 
51 1 Y 1 B VAL 12 ? B VAL 20 
52 1 Y 1 B PRO 13 ? B PRO 21 
53 1 Y 1 B VAL 14 ? B VAL 22 
54 1 Y 1 B THR 15 ? B THR 23 
55 1 Y 1 B SER 16 ? B SER 24 
56 1 Y 1 B LYS 17 ? B LYS 25 
57 1 Y 1 B ALA 18 ? B ALA 26 
58 1 Y 1 B ALA 19 ? B ALA 27 
59 1 Y 1 B PRO 20 ? B PRO 28 
60 1 Y 1 B SER 21 ? B SER 29 
61 1 Y 1 B HIS 22 ? B HIS 30 
62 1 Y 1 B GLY 23 ? B GLY 31 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
FE2 FE   FE N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
HOH O    O  N N 159 
HOH H1   H  N N 160 
HOH H2   H  N N 161 
ILE N    N  N N 162 
ILE CA   C  N S 163 
ILE C    C  N N 164 
ILE O    O  N N 165 
ILE CB   C  N S 166 
ILE CG1  C  N N 167 
ILE CG2  C  N N 168 
ILE CD1  C  N N 169 
ILE OXT  O  N N 170 
ILE H    H  N N 171 
ILE H2   H  N N 172 
ILE HA   H  N N 173 
ILE HB   H  N N 174 
ILE HG12 H  N N 175 
ILE HG13 H  N N 176 
ILE HG21 H  N N 177 
ILE HG22 H  N N 178 
ILE HG23 H  N N 179 
ILE HD11 H  N N 180 
ILE HD12 H  N N 181 
ILE HD13 H  N N 182 
ILE HXT  H  N N 183 
LEU N    N  N N 184 
LEU CA   C  N S 185 
LEU C    C  N N 186 
LEU O    O  N N 187 
LEU CB   C  N N 188 
LEU CG   C  N N 189 
LEU CD1  C  N N 190 
LEU CD2  C  N N 191 
LEU OXT  O  N N 192 
LEU H    H  N N 193 
LEU H2   H  N N 194 
LEU HA   H  N N 195 
LEU HB2  H  N N 196 
LEU HB3  H  N N 197 
LEU HG   H  N N 198 
LEU HD11 H  N N 199 
LEU HD12 H  N N 200 
LEU HD13 H  N N 201 
LEU HD21 H  N N 202 
LEU HD22 H  N N 203 
LEU HD23 H  N N 204 
LEU HXT  H  N N 205 
LYS N    N  N N 206 
LYS CA   C  N S 207 
LYS C    C  N N 208 
LYS O    O  N N 209 
LYS CB   C  N N 210 
LYS CG   C  N N 211 
LYS CD   C  N N 212 
LYS CE   C  N N 213 
LYS NZ   N  N N 214 
LYS OXT  O  N N 215 
LYS H    H  N N 216 
LYS H2   H  N N 217 
LYS HA   H  N N 218 
LYS HB2  H  N N 219 
LYS HB3  H  N N 220 
LYS HG2  H  N N 221 
LYS HG3  H  N N 222 
LYS HD2  H  N N 223 
LYS HD3  H  N N 224 
LYS HE2  H  N N 225 
LYS HE3  H  N N 226 
LYS HZ1  H  N N 227 
LYS HZ2  H  N N 228 
LYS HZ3  H  N N 229 
LYS HXT  H  N N 230 
MET N    N  N N 231 
MET CA   C  N S 232 
MET C    C  N N 233 
MET O    O  N N 234 
MET CB   C  N N 235 
MET CG   C  N N 236 
MET SD   S  N N 237 
MET CE   C  N N 238 
MET OXT  O  N N 239 
MET H    H  N N 240 
MET H2   H  N N 241 
MET HA   H  N N 242 
MET HB2  H  N N 243 
MET HB3  H  N N 244 
MET HG2  H  N N 245 
MET HG3  H  N N 246 
MET HE1  H  N N 247 
MET HE2  H  N N 248 
MET HE3  H  N N 249 
MET HXT  H  N N 250 
PHE N    N  N N 251 
PHE CA   C  N S 252 
PHE C    C  N N 253 
PHE O    O  N N 254 
PHE CB   C  N N 255 
PHE CG   C  Y N 256 
PHE CD1  C  Y N 257 
PHE CD2  C  Y N 258 
PHE CE1  C  Y N 259 
PHE CE2  C  Y N 260 
PHE CZ   C  Y N 261 
PHE OXT  O  N N 262 
PHE H    H  N N 263 
PHE H2   H  N N 264 
PHE HA   H  N N 265 
PHE HB2  H  N N 266 
PHE HB3  H  N N 267 
PHE HD1  H  N N 268 
PHE HD2  H  N N 269 
PHE HE1  H  N N 270 
PHE HE2  H  N N 271 
PHE HZ   H  N N 272 
PHE HXT  H  N N 273 
PRO N    N  N N 274 
PRO CA   C  N S 275 
PRO C    C  N N 276 
PRO O    O  N N 277 
PRO CB   C  N N 278 
PRO CG   C  N N 279 
PRO CD   C  N N 280 
PRO OXT  O  N N 281 
PRO H    H  N N 282 
PRO HA   H  N N 283 
PRO HB2  H  N N 284 
PRO HB3  H  N N 285 
PRO HG2  H  N N 286 
PRO HG3  H  N N 287 
PRO HD2  H  N N 288 
PRO HD3  H  N N 289 
PRO HXT  H  N N 290 
SER N    N  N N 291 
SER CA   C  N S 292 
SER C    C  N N 293 
SER O    O  N N 294 
SER CB   C  N N 295 
SER OG   O  N N 296 
SER OXT  O  N N 297 
SER H    H  N N 298 
SER H2   H  N N 299 
SER HA   H  N N 300 
SER HB2  H  N N 301 
SER HB3  H  N N 302 
SER HG   H  N N 303 
SER HXT  H  N N 304 
THR N    N  N N 305 
THR CA   C  N S 306 
THR C    C  N N 307 
THR O    O  N N 308 
THR CB   C  N R 309 
THR OG1  O  N N 310 
THR CG2  C  N N 311 
THR OXT  O  N N 312 
THR H    H  N N 313 
THR H2   H  N N 314 
THR HA   H  N N 315 
THR HB   H  N N 316 
THR HG1  H  N N 317 
THR HG21 H  N N 318 
THR HG22 H  N N 319 
THR HG23 H  N N 320 
THR HXT  H  N N 321 
TRP N    N  N N 322 
TRP CA   C  N S 323 
TRP C    C  N N 324 
TRP O    O  N N 325 
TRP CB   C  N N 326 
TRP CG   C  Y N 327 
TRP CD1  C  Y N 328 
TRP CD2  C  Y N 329 
TRP NE1  N  Y N 330 
TRP CE2  C  Y N 331 
TRP CE3  C  Y N 332 
TRP CZ2  C  Y N 333 
TRP CZ3  C  Y N 334 
TRP CH2  C  Y N 335 
TRP OXT  O  N N 336 
TRP H    H  N N 337 
TRP H2   H  N N 338 
TRP HA   H  N N 339 
TRP HB2  H  N N 340 
TRP HB3  H  N N 341 
TRP HD1  H  N N 342 
TRP HE1  H  N N 343 
TRP HE3  H  N N 344 
TRP HZ2  H  N N 345 
TRP HZ3  H  N N 346 
TRP HH2  H  N N 347 
TRP HXT  H  N N 348 
TYR N    N  N N 349 
TYR CA   C  N S 350 
TYR C    C  N N 351 
TYR O    O  N N 352 
TYR CB   C  N N 353 
TYR CG   C  Y N 354 
TYR CD1  C  Y N 355 
TYR CD2  C  Y N 356 
TYR CE1  C  Y N 357 
TYR CE2  C  Y N 358 
TYR CZ   C  Y N 359 
TYR OH   O  N N 360 
TYR OXT  O  N N 361 
TYR H    H  N N 362 
TYR H2   H  N N 363 
TYR HA   H  N N 364 
TYR HB2  H  N N 365 
TYR HB3  H  N N 366 
TYR HD1  H  N N 367 
TYR HD2  H  N N 368 
TYR HE1  H  N N 369 
TYR HE2  H  N N 370 
TYR HH   H  N N 371 
TYR HXT  H  N N 372 
V9L O1   O  N N 373 
V9L C1   C  Y N 374 
V9L C2   C  Y N 375 
V9L C3   C  Y N 376 
V9L C4   C  Y N 377 
V9L C5   C  Y N 378 
V9L C6   C  Y N 379 
V9L O2   O  N N 380 
V9L C7   C  N N 381 
V9L C8   C  N N 382 
V9L O3   O  N N 383 
V9L H1   H  N N 384 
V9L H2   H  N N 385 
V9L H3   H  N N 386 
V9L H4   H  N N 387 
V9L H5   H  N N 388 
V9L H6   H  N N 389 
V9L H7   H  N N 390 
V9L H8   H  N N 391 
VAL N    N  N N 392 
VAL CA   C  N S 393 
VAL C    C  N N 394 
VAL O    O  N N 395 
VAL CB   C  N N 396 
VAL CG1  C  N N 397 
VAL CG2  C  N N 398 
VAL OXT  O  N N 399 
VAL H    H  N N 400 
VAL H2   H  N N 401 
VAL HA   H  N N 402 
VAL HB   H  N N 403 
VAL HG11 H  N N 404 
VAL HG12 H  N N 405 
VAL HG13 H  N N 406 
VAL HG21 H  N N 407 
VAL HG22 H  N N 408 
VAL HG23 H  N N 409 
VAL HXT  H  N N 410 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
V9L C8  O3   doub N N 358 
V9L C8  C2   sing N N 359 
V9L C3  C2   doub Y N 360 
V9L C3  C4   sing Y N 361 
V9L C2  C1   sing Y N 362 
V9L C4  C5   doub Y N 363 
V9L C1  O1   sing N N 364 
V9L C1  C6   doub Y N 365 
V9L C5  C6   sing Y N 366 
V9L C6  O2   sing N N 367 
V9L O2  C7   sing N N 368 
V9L O1  H1   sing N N 369 
V9L C3  H2   sing N N 370 
V9L C4  H3   sing N N 371 
V9L C5  H4   sing N N 372 
V9L C7  H5   sing N N 373 
V9L C7  H6   sing N N 374 
V9L C7  H7   sing N N 375 
V9L C8  H8   sing N N 376 
VAL N   CA   sing N N 377 
VAL N   H    sing N N 378 
VAL N   H2   sing N N 379 
VAL CA  C    sing N N 380 
VAL CA  CB   sing N N 381 
VAL CA  HA   sing N N 382 
VAL C   O    doub N N 383 
VAL C   OXT  sing N N 384 
VAL CB  CG1  sing N N 385 
VAL CB  CG2  sing N N 386 
VAL CB  HB   sing N N 387 
VAL CG1 HG11 sing N N 388 
VAL CG1 HG12 sing N N 389 
VAL CG1 HG13 sing N N 390 
VAL CG2 HG21 sing N N 391 
VAL CG2 HG22 sing N N 392 
VAL CG2 HG23 sing N N 393 
VAL OXT HXT  sing N N 394 
# 
_pdbx_audit_support.funding_organization   'Austrian Science Fund' 
_pdbx_audit_support.country                Austria 
_pdbx_audit_support.grant_number           P33687 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9G8F 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013911 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.004627 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011773 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.009847 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
FE 26 26 11.7738 4.7611  7.3600 0.3072  3.5235 15.3535 2.3054 76.8805 1.2402   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0650   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . TYR A 1 32  ? 4.245   19.154  20.787  1 50.742 ? 24   TYR A N   1 
ATOM   2    C  CA  . TYR A 1 32  ? 4.796   18.161  19.814  1 52.245 ? 24   TYR A CA  1 
ATOM   3    C  C   . TYR A 1 32  ? 4.12    16.801  19.999  1 52.74  ? 24   TYR A C   1 
ATOM   4    O  O   . TYR A 1 32  ? 4.021   16.302  21.116  1 58.543 ? 24   TYR A O   1 
ATOM   5    C  CB  . TYR A 1 32  ? 6.322   17.975  19.813  1 47.632 ? 24   TYR A CB  1 
ATOM   6    C  CG  . TYR A 1 32  ? 6.819   16.978  18.767  1 48.905 ? 24   TYR A CG  1 
ATOM   7    C  CD1 . TYR A 1 32  ? 6.838   17.307  17.406  1 41.877 ? 24   TYR A CD1 1 
ATOM   8    C  CD2 . TYR A 1 32  ? 7.22    15.692  19.132  1 42.343 ? 24   TYR A CD2 1 
ATOM   9    C  CE1 . TYR A 1 32  ? 7.25    16.393  16.44   1 45.951 ? 24   TYR A CE1 1 
ATOM   10   C  CE2 . TYR A 1 32  ? 7.645   14.774  18.176  1 45.185 ? 24   TYR A CE2 1 
ATOM   11   C  CZ  . TYR A 1 32  ? 7.662   15.127  16.83   1 47.921 ? 24   TYR A CZ  1 
ATOM   12   O  OH  . TYR A 1 32  ? 8.084   14.249  15.869  1 45.524 ? 24   TYR A OH  1 
ATOM   13   N  N   . VAL A 1 33  ? 3.697   16.192  18.879  1 53.67  ? 25   VAL A N   1 
ATOM   14   C  CA  . VAL A 1 33  ? 3.204   14.819  18.877  1 50.038 ? 25   VAL A CA  1 
ATOM   15   C  C   . VAL A 1 33  ? 3.933   14.046  17.777  1 54.271 ? 25   VAL A C   1 
ATOM   16   O  O   . VAL A 1 33  ? 3.997   14.472  16.624  1 47.438 ? 25   VAL A O   1 
ATOM   17   C  CB  . VAL A 1 33  ? 1.671   14.586  18.833  1 58.352 ? 25   VAL A CB  1 
ATOM   18   C  CG1 . VAL A 1 33  ? 1.269   13.108  18.78   1 54.799 ? 25   VAL A CG1 1 
ATOM   19   C  CG2 . VAL A 1 33  ? 0.932   15.254  19.998  1 51.597 ? 25   VAL A CG2 1 
ATOM   20   N  N   . HIS A 1 34  ? 4.442   12.874  18.177  1 54.024 ? 26   HIS A N   1 
ATOM   21   C  CA  . HIS A 1 34  ? 5.132   11.927  17.323  1 41.173 ? 26   HIS A CA  1 
ATOM   22   C  C   . HIS A 1 34  ? 4.077   11.106  16.574  1 43.799 ? 26   HIS A C   1 
ATOM   23   O  O   . HIS A 1 34  ? 3.26    10.437  17.208  1 34.716 ? 26   HIS A O   1 
ATOM   24   C  CB  . HIS A 1 34  ? 5.999   11.018  18.2    1 46.619 ? 26   HIS A CB  1 
ATOM   25   C  CG  . HIS A 1 34  ? 7.147   10.43   17.476  1 41.22  ? 26   HIS A CG  1 
ATOM   26   N  ND1 . HIS A 1 34  ? 6.991   9.501   16.46   1 39.31  ? 26   HIS A ND1 1 
ATOM   27   C  CD2 . HIS A 1 34  ? 8.473   10.681  17.602  1 28.082 ? 26   HIS A CD2 1 
ATOM   28   C  CE1 . HIS A 1 34  ? 8.209   9.18    15.992  1 34.127 ? 26   HIS A CE1 1 
ATOM   29   N  NE2 . HIS A 1 34  ? 9.11    9.889   16.678  1 25.568 ? 26   HIS A NE2 1 
ATOM   30   N  N   . PRO A 1 35  ? 4.057   11.122  15.21   1 44.62  ? 27   PRO A N   1 
ATOM   31   C  CA  . PRO A 1 35  ? 3.012   10.459  14.421  1 44.18  ? 27   PRO A CA  1 
ATOM   32   C  C   . PRO A 1 35  ? 2.729   8.994   14.739  1 39.657 ? 27   PRO A C   1 
ATOM   33   O  O   . PRO A 1 35  ? 1.592   8.586   14.687  1 43.774 ? 27   PRO A O   1 
ATOM   34   C  CB  . PRO A 1 35  ? 3.379   10.702  12.961  1 45.479 ? 27   PRO A CB  1 
ATOM   35   C  CG  . PRO A 1 35  ? 4.805   11.212  13.005  1 41.484 ? 27   PRO A CG  1 
ATOM   36   C  CD  . PRO A 1 35  ? 5.006   11.864  14.354  1 50.179 ? 27   PRO A CD  1 
ATOM   37   N  N   . THR A 1 36  ? 3.746   8.208   15.094  1 37.151 ? 28   THR A N   1 
ATOM   38   C  CA  . THR A 1 36  ? 3.564   6.829   15.549  1 37.039 ? 28   THR A CA  1 
ATOM   39   C  C   . THR A 1 36  ? 2.793   6.748   16.888  1 35.245 ? 28   THR A C   1 
ATOM   40   O  O   . THR A 1 36  ? 2.16    5.725   17.167  1 27.862 ? 28   THR A O   1 
ATOM   41   C  CB  . THR A 1 36  ? 4.909   6.074   15.594  1 32.601 ? 28   THR A CB  1 
ATOM   42   O  OG1 . THR A 1 36  ? 5.681   6.681   16.628  1 28.404 ? 28   THR A OG1 1 
ATOM   43   C  CG2 . THR A 1 36  ? 5.749   6.245   14.333  1 32.304 ? 28   THR A CG2 1 
ATOM   44   N  N   . ASP A 1 37  ? 2.801   7.826   17.701  1 32.919 ? 29   ASP A N   1 
ATOM   45   C  CA  . ASP A 1 37  ? 2.123   7.798   18.994  1 35.793 ? 29   ASP A CA  1 
ATOM   46   C  C   . ASP A 1 37  ? 0.593   7.83    18.877  1 39.635 ? 29   ASP A C   1 
ATOM   47   O  O   . ASP A 1 37  ? -0.089  7.351   19.788  1 32.715 ? 29   ASP A O   1 
ATOM   48   C  CB  . ASP A 1 37  ? 2.672   8.818   19.971  1 23.566 ? 29   ASP A CB  1 
ATOM   49   C  CG  . ASP A 1 37  ? 4.112   8.568   20.387  1 26.127 ? 29   ASP A CG  1 
ATOM   50   O  OD1 . ASP A 1 37  ? 4.675   7.498   20.032  1 30.024 ? 29   ASP A OD1 1 
ATOM   51   O  OD2 . ASP A 1 37  ? 4.724   9.481   20.971  1 24.168 ? 29   ASP A OD2 1 
ATOM   52   N  N   . ILE A 1 38  ? 0.073   8.313   17.739  1 48.177 ? 30   ILE A N   1 
ATOM   53   C  CA  . ILE A 1 38  ? -1.374  8.392   17.519  1 52.505 ? 30   ILE A CA  1 
ATOM   54   C  C   . ILE A 1 38  ? -1.901  7.137   16.815  1 51.948 ? 30   ILE A C   1 
ATOM   55   O  O   . ILE A 1 38  ? -3.118  7.001   16.629  1 51.264 ? 30   ILE A O   1 
ATOM   56   C  CB  . ILE A 1 38  ? -1.843  9.707   16.848  1 45.157 ? 30   ILE A CB  1 
ATOM   57   C  CG1 . ILE A 1 38  ? -1.297  9.926   15.404  1 42.857 ? 30   ILE A CG1 1 
ATOM   58   C  CG2 . ILE A 1 38  ? -1.596  10.909  17.76   1 44.197 ? 30   ILE A CG2 1 
ATOM   59   C  CD1 . ILE A 1 38  ? -2.062  9.24    14.28   1 43.879 ? 30   ILE A CD1 1 
ATOM   60   N  N   . LEU A 1 39  ? -0.982  6.241   16.408  1 41.304 ? 31   LEU A N   1 
ATOM   61   C  CA  . LEU A 1 39  ? -1.333  4.908   15.956  1 34.752 ? 31   LEU A CA  1 
ATOM   62   C  C   . LEU A 1 39  ? -2.014  4.175   17.102  1 38.614 ? 31   LEU A C   1 
ATOM   63   O  O   . LEU A 1 39  ? -1.549  4.293   18.248  1 41.836 ? 31   LEU A O   1 
ATOM   64   C  CB  . LEU A 1 39  ? -0.155  4.102   15.394  1 34.616 ? 31   LEU A CB  1 
ATOM   65   C  CG  . LEU A 1 39  ? 0.541   4.601   14.117  1 36.744 ? 31   LEU A CG  1 
ATOM   66   C  CD1 . LEU A 1 39  ? 1.8     3.786   13.832  1 42.897 ? 31   LEU A CD1 1 
ATOM   67   C  CD2 . LEU A 1 39  ? -0.323  4.551   12.86   1 42.579 ? 31   LEU A CD2 1 
ATOM   68   N  N   . PRO A 1 40  ? -3.102  3.401   16.802  1 40.019 ? 32   PRO A N   1 
ATOM   69   C  CA  . PRO A 1 40  ? -3.891  2.683   17.794  1 38.357 ? 32   PRO A CA  1 
ATOM   70   C  C   . PRO A 1 40  ? -3.203  1.497   18.472  1 37.17  ? 32   PRO A C   1 
ATOM   71   O  O   . PRO A 1 40  ? -2.62   0.597   17.859  1 29.193 ? 32   PRO A O   1 
ATOM   72   C  CB  . PRO A 1 40  ? -5.159  2.269   17.042  1 42.93  ? 32   PRO A CB  1 
ATOM   73   C  CG  . PRO A 1 40  ? -4.602  2.061   15.652  1 48.897 ? 32   PRO A CG  1 
ATOM   74   C  CD  . PRO A 1 40  ? -3.663  3.215   15.45   1 47.049 ? 32   PRO A CD  1 
ATOM   75   N  N   . SER A 1 41  ? -3.259  1.597   19.786  1 35.176 ? 33   SER A N   1 
ATOM   76   C  CA  . SER A 1 41  ? -3.103  0.512   20.711  1 34.424 ? 33   SER A CA  1 
ATOM   77   C  C   . SER A 1 41  ? -4.451  -0.211  20.825  1 35.529 ? 33   SER A C   1 
ATOM   78   O  O   . SER A 1 41  ? -5.532  0.413   20.824  1 38.16  ? 33   SER A O   1 
ATOM   79   C  CB  . SER A 1 41  ? -2.743  1.119   22.023  1 39.189 ? 33   SER A CB  1 
ATOM   80   O  OG  . SER A 1 41  ? -2.437  0.096   22.936  1 28.021 ? 33   SER A OG  1 
ATOM   81   N  N   . GLY A 1 42  ? -4.353  -1.54   20.94   1 26.644 ? 34   GLY A N   1 
ATOM   82   C  CA  . GLY A 1 42  ? -5.483  -2.385  21.278  1 25.856 ? 34   GLY A CA  1 
ATOM   83   C  C   . GLY A 1 42  ? -5.474  -2.726  22.774  1 26.658 ? 34   GLY A C   1 
ATOM   84   O  O   . GLY A 1 42  ? -6.171  -3.668  23.176  1 23.054 ? 34   GLY A O   1 
ATOM   85   N  N   . TRP A 1 43  ? -4.647  -1.999  23.556  1 25.421 ? 35   TRP A N   1 
ATOM   86   C  CA  . TRP A 1 43  ? -4.568  -2.165  25.004  1 25.273 ? 35   TRP A CA  1 
ATOM   87   C  C   . TRP A 1 43  ? -5.547  -1.247  25.733  1 28.528 ? 35   TRP A C   1 
ATOM   88   O  O   . TRP A 1 43  ? -5.535  -0.025  25.549  1 28     ? 35   TRP A O   1 
ATOM   89   C  CB  . TRP A 1 43  ? -3.141  -1.906  25.505  1 23.416 ? 35   TRP A CB  1 
ATOM   90   C  CG  . TRP A 1 43  ? -2.277  -3.13   25.491  1 19.911 ? 35   TRP A CG  1 
ATOM   91   C  CD1 . TRP A 1 43  ? -1.638  -3.706  24.429  1 22.023 ? 35   TRP A CD1 1 
ATOM   92   C  CD2 . TRP A 1 43  ? -1.981  -3.942  26.635  1 20.995 ? 35   TRP A CD2 1 
ATOM   93   N  NE1 . TRP A 1 43  ? -0.959  -4.836  24.831  1 21.457 ? 35   TRP A NE1 1 
ATOM   94   C  CE2 . TRP A 1 43  ? -1.152  -5.003  26.176  1 21.156 ? 35   TRP A CE2 1 
ATOM   95   C  CE3 . TRP A 1 43  ? -2.318  -3.857  27.993  1 20.395 ? 35   TRP A CE3 1 
ATOM   96   C  CZ2 . TRP A 1 43  ? -0.69   -5.988  27.051  1 24.226 ? 35   TRP A CZ2 1 
ATOM   97   C  CZ3 . TRP A 1 43  ? -1.85   -4.835  28.859  1 21.721 ? 35   TRP A CZ3 1 
ATOM   98   C  CH2 . TRP A 1 43  ? -1.061  -5.883  28.383  1 21.958 ? 35   TRP A CH2 1 
ATOM   99   N  N   . PRO A 1 44  ? -6.372  -1.788  26.657  1 23.058 ? 36   PRO A N   1 
ATOM   100  C  CA  . PRO A 1 44  ? -7.069  -0.955  27.621  1 26.555 ? 36   PRO A CA  1 
ATOM   101  C  C   . PRO A 1 44  ? -6.108  -0.406  28.664  1 23.539 ? 36   PRO A C   1 
ATOM   102  O  O   . PRO A 1 44  ? -4.949  -0.849  28.776  1 25.208 ? 36   PRO A O   1 
ATOM   103  C  CB  . PRO A 1 44  ? -8.1    -1.917  28.206  1 30.861 ? 36   PRO A CB  1 
ATOM   104  C  CG  . PRO A 1 44  ? -7.28   -3.197  28.226  1 22.467 ? 36   PRO A CG  1 
ATOM   105  C  CD  . PRO A 1 44  ? -6.661  -3.215  26.86   1 19.831 ? 36   PRO A CD  1 
ATOM   106  N  N   . THR A 1 45  ? -6.599  0.575   29.411  1 24.022 ? 37   THR A N   1 
ATOM   107  C  CA  . THR A 1 45  ? -5.837  1.05    30.554  1 25.088 ? 37   THR A CA  1 
ATOM   108  C  C   . THR A 1 45  ? -5.738  -0.056  31.594  1 24.243 ? 37   THR A C   1 
ATOM   109  O  O   . THR A 1 45  ? -6.748  -0.449  32.191  1 23.202 ? 37   THR A O   1 
ATOM   110  C  CB  . THR A 1 45  ? -6.444  2.317   31.154  1 26.258 ? 37   THR A CB  1 
ATOM   111  O  OG1 . THR A 1 45  ? -6.586  3.111   29.976  1 25.547 ? 37   THR A OG1 1 
ATOM   112  C  CG2 . THR A 1 45  ? -5.468  2.913   32.16   1 25.062 ? 37   THR A CG2 1 
ATOM   113  N  N   . ALA A 1 46  ? -4.531  -0.581  31.768  1 22.564 ? 38   ALA A N   1 
ATOM   114  C  CA  . ALA A 1 46  ? -4.306  -1.66   32.727  1 20.662 ? 38   ALA A CA  1 
ATOM   115  C  C   . ALA A 1 46  ? -3.454  -1.141  33.882  1 18.204 ? 38   ALA A C   1 
ATOM   116  O  O   . ALA A 1 46  ? -2.197  -1.172  33.803  1 17.431 ? 38   ALA A O   1 
ATOM   117  C  CB  . ALA A 1 46  ? -3.703  -2.877  32.051  1 23.015 ? 38   ALA A CB  1 
ATOM   118  N  N   . THR A 1 47  ? -4.124  -0.603  34.92   1 19.595 ? 39   THR A N   1 
ATOM   119  C  CA  . THR A 1 47  ? -3.393  0.028   36.013  1 20.869 ? 39   THR A CA  1 
ATOM   120  C  C   . THR A 1 47  ? -2.851  -1.032  36.985  1 22.254 ? 39   THR A C   1 
ATOM   121  O  O   . THR A 1 47  ? -3.357  -2.161  37.039  1 22.618 ? 39   THR A O   1 
ATOM   122  C  CB  . THR A 1 47  ? -4.173  1.14    36.74   1 24.023 ? 39   THR A CB  1 
ATOM   123  O  OG1 . THR A 1 47  ? -5.057  0.479   37.648  1 23.013 ? 39   THR A OG1 1 
ATOM   124  C  CG2 . THR A 1 47  ? -4.782  2.193   35.826  1 19.114 ? 39   THR A CG2 1 
ATOM   125  N  N   . ASP A 1 48  ? -1.824  -0.636  37.741  1 15.849 ? 40   ASP A N   1 
ATOM   126  C  CA  . ASP A 1 48  ? -1.444  -1.308  38.97   1 14.559 ? 40   ASP A CA  1 
ATOM   127  C  C   . ASP A 1 48  ? -1.872  -0.448  40.155  1 12.451 ? 40   ASP A C   1 
ATOM   128  O  O   . ASP A 1 48  ? -2.374  0.675   39.985  1 17.962 ? 40   ASP A O   1 
ATOM   129  C  CB  . ASP A 1 48  ? 0.041   -1.692  38.914  1 18.11  ? 40   ASP A CB  1 
ATOM   130  C  CG  . ASP A 1 48  ? 0.981   -0.491  38.861  1 22.714 ? 40   ASP A CG  1 
ATOM   131  O  OD1 . ASP A 1 48  ? 0.827   0.415   39.702  1 22.014 ? 40   ASP A OD1 1 
ATOM   132  O  OD2 . ASP A 1 48  ? 1.815   -0.422  37.946  1 24.538 ? 40   ASP A OD2 1 
ATOM   133  N  N   . LEU A 1 49  ? -1.648  -0.937  41.383  1 15.61  ? 41   LEU A N   1 
ATOM   134  C  CA  . LEU A 1 49  ? -2.092  -0.283  42.606  1 14.279 ? 41   LEU A CA  1 
ATOM   135  C  C   . LEU A 1 49  ? -1.643  1.163   42.705  1 17.673 ? 41   LEU A C   1 
ATOM   136  O  O   . LEU A 1 49  ? -2.374  1.966   43.312  1 18.991 ? 41   LEU A O   1 
ATOM   137  C  CB  . LEU A 1 49  ? -1.91   -0.963  43.965  1 14.878 ? 41   LEU A CB  1 
ATOM   138  C  CG  . LEU A 1 49  ? -2.968  -2.001  44.364  1 17.104 ? 41   LEU A CG  1 
ATOM   139  C  CD1 . LEU A 1 49  ? -2.556  -2.536  45.707  1 18.88  ? 41   LEU A CD1 1 
ATOM   140  C  CD2 . LEU A 1 49  ? -4.329  -1.341  44.498  1 13.362 ? 41   LEU A CD2 1 
ATOM   141  N  N   . SER A 1 50  ? -0.432  1.463   42.18   1 16.85  ? 42   SER A N   1 
ATOM   142  C  CA  . SER A 1 50  ? 0.168   2.802   42.252  1 17.188 ? 42   SER A CA  1 
ATOM   143  C  C   . SER A 1 50  ? -0.573  3.818   41.384  1 18.912 ? 42   SER A C   1 
ATOM   144  O  O   . SER A 1 50  ? -0.426  5.039   41.576  1 20.012 ? 42   SER A O   1 
ATOM   145  C  CB  . SER A 1 50  ? 1.69    2.704   41.915  1 15.511 ? 42   SER A CB  1 
ATOM   146  O  OG  . SER A 1 50  ? 1.949   2.734   40.487  1 16.616 ? 42   SER A OG  1 
ATOM   147  N  N   . GLY A 1 51  ? -1.29   3.317   40.372  1 18.963 ? 43   GLY A N   1 
ATOM   148  C  CA  . GLY A 1 51  ? -1.999  4.098   39.399  1 17.844 ? 43   GLY A CA  1 
ATOM   149  C  C   . GLY A 1 51  ? -1.249  4.081   38.065  1 20.612 ? 43   GLY A C   1 
ATOM   150  O  O   . GLY A 1 51  ? -1.744  4.59    37.063  1 23.163 ? 43   GLY A O   1 
ATOM   151  N  N   . GLY A 1 52  ? -0.055  3.484   38.07   1 17.84  ? 44   GLY A N   1 
ATOM   152  C  CA  . GLY A 1 52  ? 0.784   3.352   36.889  1 18.752 ? 44   GLY A CA  1 
ATOM   153  C  C   . GLY A 1 52  ? 0.105   2.49    35.849  1 17.918 ? 44   GLY A C   1 
ATOM   154  O  O   . GLY A 1 52  ? -0.507  1.481   36.217  1 16.961 ? 44   GLY A O   1 
ATOM   155  N  N   . ALA A 1 53  ? 0.279   2.828   34.571  1 17.065 ? 45   ALA A N   1 
ATOM   156  C  CA  . ALA A 1 53  ? -0.456  2.046   33.581  1 16.49  ? 45   ALA A CA  1 
ATOM   157  C  C   . ALA A 1 53  ? 0.418   1.504   32.467  1 19.25  ? 45   ALA A C   1 
ATOM   158  O  O   . ALA A 1 53  ? -0.123  1.108   31.431  1 21.719 ? 45   ALA A O   1 
ATOM   159  C  CB  . ALA A 1 53  ? -1.608  2.882   33.001  1 24.241 ? 45   ALA A CB  1 
ATOM   160  N  N   . GLN A 1 54  ? 1.762   1.46    32.651  1 18.31  ? 46   GLN A N   1 
ATOM   161  C  CA  . GLN A 1 54  ? 2.552   0.985   31.545  1 18.167 ? 46   GLN A CA  1 
ATOM   162  C  C   . GLN A 1 54  ? 2.719   -0.537  31.679  1 16.678 ? 46   GLN A C   1 
ATOM   163  O  O   . GLN A 1 54  ? 3.328   -0.964  32.674  1 16.535 ? 46   GLN A O   1 
ATOM   164  C  CB  . GLN A 1 54  ? 3.824   1.84    31.487  1 21.549 ? 46   GLN A CB  1 
ATOM   165  C  CG  . GLN A 1 54  ? 4.883   1.265   30.564  1 32.451 ? 46   GLN A CG  1 
ATOM   166  C  CD  . GLN A 1 54  ? 4.503   1.215   29.105  1 38.231 ? 46   GLN A CD  1 
ATOM   167  O  OE1 . GLN A 1 54  ? 3.795   2.094   28.58   1 34.624 ? 46   GLN A OE1 1 
ATOM   168  N  NE2 . GLN A 1 54  ? 4.939   0.122   28.477  1 32.109 ? 46   GLN A NE2 1 
ATOM   169  N  N   . PRO A 1 55  ? 2.257   -1.368  30.701  1 14.856 ? 47   PRO A N   1 
ATOM   170  C  CA  . PRO A 1 55  ? 2.565   -2.797  30.7    1 14.816 ? 47   PRO A CA  1 
ATOM   171  C  C   . PRO A 1 55  ? 4.08    -2.999  30.604  1 13.383 ? 47   PRO A C   1 
ATOM   172  O  O   . PRO A 1 55  ? 4.711   -2.221  29.881  1 13.106 ? 47   PRO A O   1 
ATOM   173  C  CB  . PRO A 1 55  ? 1.93    -3.278  29.414  1 17.253 ? 47   PRO A CB  1 
ATOM   174  C  CG  . PRO A 1 55  ? 0.723   -2.353  29.307  1 16.772 ? 47   PRO A CG  1 
ATOM   175  C  CD  . PRO A 1 55  ? 1.386   -1.019  29.558  1 15.821 ? 47   PRO A CD  1 
ATOM   176  N  N   . ARG A 1 56  ? 4.614   -4.029  31.291  1 14.348 ? 48   ARG A N   1 
ATOM   177  C  CA  . ARG A 1 56  ? 6.052   -4.267  31.296  1 13.483 ? 48   ARG A CA  1 
ATOM   178  C  C   . ARG A 1 56  ? 6.301   -5.635  30.66   1 17.16  ? 48   ARG A C   1 
ATOM   179  O  O   . ARG A 1 56  ? 6.559   -5.688  29.458  1 17.042 ? 48   ARG A O   1 
ATOM   180  C  CB  . ARG A 1 56  ? 6.667   -4.082  32.685  1 15.328 ? 48   ARG A CB  1 
ATOM   181  C  CG  . ARG A 1 56  ? 6.617   -2.653  33.218  1 19.395 ? 48   ARG A CG  1 
ATOM   182  C  CD  . ARG A 1 56  ? 7.329   -1.66   32.325  1 17.189 ? 48   ARG A CD  1 
ATOM   183  N  NE  . ARG A 1 56  ? 7.044   -0.389  32.995  1 18.014 ? 48   ARG A NE  1 
ATOM   184  C  CZ  . ARG A 1 56  ? 7.464   0.827   32.635  1 22.839 ? 48   ARG A CZ  1 
ATOM   185  N  NH1 . ARG A 1 56  ? 8.267   0.933   31.574  1 21.546 ? 48   ARG A NH1 1 
ATOM   186  N  NH2 . ARG A 1 56  ? 7.024   1.876   33.336  1 19.969 ? 48   ARG A NH2 1 
ATOM   187  N  N   . ARG A 1 57  ? 6.003   -6.706  31.415  1 14.784 ? 49   ARG A N   1 
ATOM   188  C  CA  . ARG A 1 57  ? 5.807   -8.067  30.891  1 15.226 ? 49   ARG A CA  1 
ATOM   189  C  C   . ARG A 1 57  ? 7.09    -8.742  30.397  1 16.199 ? 49   ARG A C   1 
ATOM   190  O  O   . ARG A 1 57  ? 7.016   -9.765  29.731  1 20.776 ? 49   ARG A O   1 
ATOM   191  C  CB  . ARG A 1 57  ? 4.76    -8.242  29.761  1 16.462 ? 49   ARG A CB  1 
ATOM   192  C  CG  . ARG A 1 57  ? 3.524   -7.426  30.098  1 13.33  ? 49   ARG A CG  1 
ATOM   193  C  CD  . ARG A 1 57  ? 2.579   -7.426  28.925  1 14.693 ? 49   ARG A CD  1 
ATOM   194  N  NE  . ARG A 1 57  ? 3.12    -6.834  27.696  1 18.408 ? 49   ARG A NE  1 
ATOM   195  C  CZ  . ARG A 1 57  ? 3.003   -7.302  26.446  1 15.841 ? 49   ARG A CZ  1 
ATOM   196  N  NH1 . ARG A 1 57  ? 2.286   -8.333  26.128  1 15.488 ? 49   ARG A NH1 1 
ATOM   197  N  NH2 . ARG A 1 57  ? 3.598   -6.707  25.441  1 13.92  ? 49   ARG A NH2 1 
ATOM   198  N  N   . PHE A 1 58  ? 8.255   -8.251  30.791  1 14.504 ? 50   PHE A N   1 
ATOM   199  C  CA  . PHE A 1 58  ? 9.438   -8.978  30.357  1 17.613 ? 50   PHE A CA  1 
ATOM   200  C  C   . PHE A 1 58  ? 9.701   -10.142 31.318  1 13.394 ? 50   PHE A C   1 
ATOM   201  O  O   . PHE A 1 58  ? 9.425   -10.08  32.523  1 15.152 ? 50   PHE A O   1 
ATOM   202  C  CB  . PHE A 1 58  ? 10.644  -8.041  30.198  1 24.373 ? 50   PHE A CB  1 
ATOM   203  C  CG  . PHE A 1 58  ? 10.759  -7.008  31.311  1 24.384 ? 50   PHE A CG  1 
ATOM   204  C  CD1 . PHE A 1 58  ? 11.209  -7.35   32.58   1 31.565 ? 50   PHE A CD1 1 
ATOM   205  C  CD2 . PHE A 1 58  ? 10.435  -5.659  31.069  1 34.131 ? 50   PHE A CD2 1 
ATOM   206  C  CE1 . PHE A 1 58  ? 11.29   -6.376  33.574  1 35.299 ? 50   PHE A CE1 1 
ATOM   207  C  CE2 . PHE A 1 58  ? 10.575  -4.674  32.062  1 25.149 ? 50   PHE A CE2 1 
ATOM   208  C  CZ  . PHE A 1 58  ? 10.999  -5.048  33.3    1 32.711 ? 50   PHE A CZ  1 
ATOM   209  N  N   . GLU A 1 59  ? 10.289  -11.191 30.74   1 12.261 ? 51   GLU A N   1 
ATOM   210  C  CA  . GLU A 1 59  ? 10.739  -12.332 31.531  1 12.234 ? 51   GLU A CA  1 
ATOM   211  C  C   . GLU A 1 59  ? 12.196  -12.596 31.198  1 10.639 ? 51   GLU A C   1 
ATOM   212  O  O   . GLU A 1 59  ? 12.568  -12.813 30.026  1 9.789  ? 51   GLU A O   1 
ATOM   213  C  CB  . GLU A 1 59  ? 9.884   -13.571 31.247  1 12.808 ? 51   GLU A CB  1 
ATOM   214  C  CG  . GLU A 1 59  ? 8.369   -13.338 31.352  1 15.518 ? 51   GLU A CG  1 
ATOM   215  C  CD  . GLU A 1 59  ? 7.61    -14.619 31.073  1 14.037 ? 51   GLU A CD  1 
ATOM   216  O  OE1 . GLU A 1 59  ? 7.443   -15.059 29.905  1 13.593 ? 51   GLU A OE1 1 
ATOM   217  O  OE2 . GLU A 1 59  ? 7.311   -15.274 32.075  1 11.057 ? 51   GLU A OE2 1 
ATOM   218  N  N   . GLY A 1 60  ? 13.044  -12.538 32.204  1 10.387 ? 52   GLY A N   1 
ATOM   219  C  CA  . GLY A 1 60  ? 14.468  -12.721 31.976  1 11.24  ? 52   GLY A CA  1 
ATOM   220  C  C   . GLY A 1 60  ? 15.352  -12.268 33.13   1 13.091 ? 52   GLY A C   1 
ATOM   221  O  O   . GLY A 1 60  ? 14.845  -12.115 34.257  1 13.812 ? 52   GLY A O   1 
ATOM   222  N  N   . THR A 1 61  ? 16.651  -12.04  32.82   1 14.439 ? 53   THR A N   1 
ATOM   223  C  CA  . THR A 1 61  ? 17.672  -11.792 33.847  1 12.074 ? 53   THR A CA  1 
ATOM   224  C  C   . THR A 1 61  ? 18.58   -10.63  33.482  1 11.215 ? 53   THR A C   1 
ATOM   225  O  O   . THR A 1 61  ? 18.738  -10.262 32.341  1 10.846 ? 53   THR A O   1 
ATOM   226  C  CB  . THR A 1 61  ? 18.509  -13.06  34.145  1 12.036 ? 53   THR A CB  1 
ATOM   227  O  OG1 . THR A 1 61  ? 19.134  -13.418 32.911  1 12.794 ? 53   THR A OG1 1 
ATOM   228  C  CG2 . THR A 1 61  ? 17.593  -14.235 34.53   1 12.233 ? 53   THR A CG2 1 
ATOM   229  N  N   . ILE A 1 62  ? 19.205  -10.101 34.525  1 11.251 ? 54   ILE A N   1 
ATOM   230  C  CA  . ILE A 1 62  ? 20.424  -9.279  34.471  1 13.081 ? 54   ILE A CA  1 
ATOM   231  C  C   . ILE A 1 62  ? 21.407  -9.832  35.497  1 15.098 ? 54   ILE A C   1 
ATOM   232  O  O   . ILE A 1 62  ? 21.079  -9.909  36.686  1 17.02  ? 54   ILE A O   1 
ATOM   233  C  CB  . ILE A 1 62  ? 20.056  -7.808  34.82   1 13.989 ? 54   ILE A CB  1 
ATOM   234  C  CG1 . ILE A 1 62  ? 19.048  -7.234  33.828  1 15.278 ? 54   ILE A CG1 1 
ATOM   235  C  CG2 . ILE A 1 62  ? 21.342  -6.97   34.885  1 15.866 ? 54   ILE A CG2 1 
ATOM   236  C  CD1 . ILE A 1 62  ? 18.53   -5.877  34.255  1 18.171 ? 54   ILE A CD1 1 
ATOM   237  N  N   . PHE A 1 63  ? 22.586  -10.251 35.004  1 14.656 ? 55   PHE A N   1 
ATOM   238  C  CA  . PHE A 1 63  ? 23.623  -10.707 35.923  1 15.385 ? 55   PHE A CA  1 
ATOM   239  C  C   . PHE A 1 63  ? 24.451  -9.497  36.358  1 15.344 ? 55   PHE A C   1 
ATOM   240  O  O   . PHE A 1 63  ? 24.912  -8.737  35.508  1 12.969 ? 55   PHE A O   1 
ATOM   241  C  CB  . PHE A 1 63  ? 24.48   -11.693 35.145  1 15.166 ? 55   PHE A CB  1 
ATOM   242  C  CG  . PHE A 1 63  ? 25.654  -12.256 35.937  1 17.052 ? 55   PHE A CG  1 
ATOM   243  C  CD1 . PHE A 1 63  ? 25.477  -13.405 36.727  1 18.771 ? 55   PHE A CD1 1 
ATOM   244  C  CD2 . PHE A 1 63  ? 26.922  -11.681 35.864  1 18.126 ? 55   PHE A CD2 1 
ATOM   245  C  CE1 . PHE A 1 63  ? 26.54   -13.935 37.465  1 16.567 ? 55   PHE A CE1 1 
ATOM   246  C  CE2 . PHE A 1 63  ? 27.997  -12.226 36.566  1 17.724 ? 55   PHE A CE2 1 
ATOM   247  C  CZ  . PHE A 1 63  ? 27.801  -13.35  37.37   1 17.035 ? 55   PHE A CZ  1 
ATOM   248  N  N   . ASP A 1 64  ? 24.711  -9.396  37.674  1 15.625 ? 56   ASP A N   1 
ATOM   249  C  CA  . ASP A 1 64  ? 25.561  -8.327  38.164  1 15.267 ? 56   ASP A CA  1 
ATOM   250  C  C   . ASP A 1 64  ? 24.902  -6.973  37.905  1 16.031 ? 56   ASP A C   1 
ATOM   251  O  O   . ASP A 1 64  ? 25.47   -6.134  37.208  1 17.215 ? 56   ASP A O   1 
ATOM   252  C  CB  . ASP A 1 64  ? 27.022  -8.505  37.738  1 18.609 ? 56   ASP A CB  1 
ATOM   253  C  CG  . ASP A 1 64  ? 28.041  -7.878  38.693  1 25.265 ? 56   ASP A CG  1 
ATOM   254  O  OD1 . ASP A 1 64  ? 27.639  -7.451  39.784  1 29.715 ? 56   ASP A OD1 1 
ATOM   255  O  OD2 . ASP A 1 64  ? 29.265  -7.853  38.375  1 27.38  ? 56   ASP A OD2 1 
ATOM   256  N  N   . VAL A 1 65  ? 23.667  -6.795  38.451  1 15.125 ? 57   VAL A N   1 
ATOM   257  C  CA  . VAL A 1 65  ? 22.916  -5.523  38.372  1 15.908 ? 57   VAL A CA  1 
ATOM   258  C  C   . VAL A 1 65  ? 23.8    -4.322  38.783  1 17.095 ? 57   VAL A C   1 
ATOM   259  O  O   . VAL A 1 65  ? 24.517  -4.374  39.784  1 14.866 ? 57   VAL A O   1 
ATOM   260  C  CB  . VAL A 1 65  ? 21.535  -5.579  39.048  1 15.781 ? 57   VAL A CB  1 
ATOM   261  C  CG1 . VAL A 1 65  ? 20.67   -4.341  38.784  1 15.085 ? 57   VAL A CG1 1 
ATOM   262  C  CG2 . VAL A 1 65  ? 20.757  -6.837  38.625  1 15.605 ? 57   VAL A CG2 1 
ATOM   263  N  N   . MET A 1 66  ? 23.779  -3.261  37.981  1 16.201 ? 58   MET A N   1 
ATOM   264  C  CA  . MET A 1 66  ? 24.514  -2.038  38.301  1 22.657 ? 58   MET A CA  1 
ATOM   265  C  C   . MET A 1 66  ? 24.135  -1.503  39.689  1 21.407 ? 58   MET A C   1 
ATOM   266  O  O   . MET A 1 66  ? 22.954  -1.447  40.018  1 17.612 ? 58   MET A O   1 
ATOM   267  C  CB  . MET A 1 66  ? 24.213  -0.998  37.224  1 22.231 ? 58   MET A CB  1 
ATOM   268  C  CG  . MET A 1 66  ? 24.885  0.321   37.413  1 36.484 ? 58   MET A CG  1 
ATOM   269  S  SD  . MET A 1 66  ? 24.766  1.308   35.896  1 50.703 ? 58   MET A SD  1 
ATOM   270  C  CE  . MET A 1 66  ? 24.269  0.058   34.728  1 17.071 ? 58   MET A CE  1 
ATOM   271  N  N   . THR A 1 67  ? 25.151  -1.217  40.539  1 16.487 ? 59   THR A N   1 
ATOM   272  C  CA  . THR A 1 67  ? 24.834  -0.651  41.852  1 21.681 ? 59   THR A CA  1 
ATOM   273  C  C   . THR A 1 67  ? 25.533  0.709   42.055  1 23.352 ? 59   THR A C   1 
ATOM   274  O  O   . THR A 1 67  ? 26.561  1.005   41.411  1 27.929 ? 59   THR A O   1 
ATOM   275  C  CB  . THR A 1 67  ? 25.063  -1.662  42.982  1 18.652 ? 59   THR A CB  1 
ATOM   276  O  OG1 . THR A 1 67  ? 26.478  -1.791  42.982  1 28.584 ? 59   THR A OG1 1 
ATOM   277  C  CG2 . THR A 1 67  ? 24.404  -3.019  42.809  1 16.213 ? 59   THR A CG2 1 
ATOM   278  N  N   . ARG A 1 68  ? 24.89   1.582   42.845  1 22.457 ? 60   ARG A N   1 
ATOM   279  C  CA  . ARG A 1 68  ? 25.477  2.832   43.282  1 20.253 ? 60   ARG A CA  1 
ATOM   280  C  C   . ARG A 1 68  ? 25.697  2.668   44.795  1 23.976 ? 60   ARG A C   1 
ATOM   281  O  O   . ARG A 1 68  ? 24.825  2.132   45.498  1 19.651 ? 60   ARG A O   1 
ATOM   282  C  CB  . ARG A 1 68  ? 24.639  4.088   42.986  1 20.062 ? 60   ARG A CB  1 
ATOM   283  C  CG  . ARG A 1 68  ? 24.36   4.337   41.5    1 20.082 ? 60   ARG A CG  1 
ATOM   284  C  CD  . ARG A 1 68  ? 23.66   5.642   41.268  1 21.043 ? 60   ARG A CD  1 
ATOM   285  N  NE  . ARG A 1 68  ? 22.431  5.959   42.016  1 20.762 ? 60   ARG A NE  1 
ATOM   286  C  CZ  . ARG A 1 68  ? 21.206  5.469   41.71   1 21.187 ? 60   ARG A CZ  1 
ATOM   287  N  NH1 . ARG A 1 68  ? 21.066  4.607   40.681  1 23.451 ? 60   ARG A NH1 1 
ATOM   288  N  NH2 . ARG A 1 68  ? 20.143  5.873   42.402  1 22.026 ? 60   ARG A NH2 1 
ATOM   289  N  N   . GLY A 1 69  ? 26.875  3.098   45.278  1 21.599 ? 61   GLY A N   1 
ATOM   290  C  CA  . GLY A 1 69  ? 27.261  2.884   46.676  1 26.076 ? 61   GLY A CA  1 
ATOM   291  C  C   . GLY A 1 69  ? 27.717  1.453   46.899  1 22.567 ? 61   GLY A C   1 
ATOM   292  O  O   . GLY A 1 69  ? 27.996  0.761   45.929  1 27.928 ? 61   GLY A O   1 
ATOM   293  N  N   . THR A 1 70  ? 27.707  0.99    48.162  1 22.07  ? 62   THR A N   1 
ATOM   294  C  CA  . THR A 1 70  ? 28.257  -0.299  48.518  1 27.392 ? 62   THR A CA  1 
ATOM   295  C  C   . THR A 1 70  ? 27.138  -1.192  49.063  1 29.599 ? 62   THR A C   1 
ATOM   296  O  O   . THR A 1 70  ? 26.471  -0.813  50.041  1 29.618 ? 62   THR A O   1 
ATOM   297  C  CB  . THR A 1 70  ? 29.38   -0.09   49.554  1 36.811 ? 62   THR A CB  1 
ATOM   298  O  OG1 . THR A 1 70  ? 30.509  0.466   48.87   1 37.791 ? 62   THR A OG1 1 
ATOM   299  C  CG2 . THR A 1 70  ? 29.771  -1.352  50.305  1 28.398 ? 62   THR A CG2 1 
ATOM   300  N  N   . ILE A 1 71  ? 26.988  -2.36   48.438  1 22.518 ? 63   ILE A N   1 
ATOM   301  C  CA  . ILE A 1 71  ? 26.052  -3.403  48.893  1 26.501 ? 63   ILE A CA  1 
ATOM   302  C  C   . ILE A 1 71  ? 26.606  -4.064  50.154  1 22.427 ? 63   ILE A C   1 
ATOM   303  O  O   . ILE A 1 71  ? 27.696  -4.654  50.118  1 21.028 ? 63   ILE A O   1 
ATOM   304  C  CB  . ILE A 1 71  ? 25.822  -4.437  47.783  1 21.515 ? 63   ILE A CB  1 
ATOM   305  C  CG1 . ILE A 1 71  ? 25.184  -3.817  46.487  1 21.412 ? 63   ILE A CG1 1 
ATOM   306  C  CG2 . ILE A 1 71  ? 25.09   -5.705  48.265  1 21.374 ? 63   ILE A CG2 1 
ATOM   307  C  CD1 . ILE A 1 71  ? 23.834  -3.149  46.619  1 19.404 ? 63   ILE A CD1 1 
ATOM   308  N  N   . PRO A 1 72  ? 25.89   -4.011  51.302  1 23.998 ? 64   PRO A N   1 
ATOM   309  C  CA  . PRO A 1 72  ? 26.419  -4.637  52.512  1 28.365 ? 64   PRO A CA  1 
ATOM   310  C  C   . PRO A 1 72  ? 26.697  -6.126  52.312  1 27.223 ? 64   PRO A C   1 
ATOM   311  O  O   . PRO A 1 72  ? 25.845  -6.851  51.805  1 29.493 ? 64   PRO A O   1 
ATOM   312  C  CB  . PRO A 1 72  ? 25.316  -4.381  53.548  1 26.201 ? 64   PRO A CB  1 
ATOM   313  C  CG  . PRO A 1 72  ? 24.392  -3.325  52.989  1 23.629 ? 64   PRO A CG  1 
ATOM   314  C  CD  . PRO A 1 72  ? 24.569  -3.369  51.483  1 20.823 ? 64   PRO A CD  1 
ATOM   315  N  N   . LYS A 1 73  ? 27.89   -6.59   52.707  1 25.258 ? 65   LYS A N   1 
ATOM   316  C  CA  . LYS A 1 73  ? 28.234  -8.002  52.667  1 26.857 ? 65   LYS A CA  1 
ATOM   317  C  C   . LYS A 1 73  ? 27.355  -8.834  53.594  1 22.67  ? 65   LYS A C   1 
ATOM   318  O  O   . LYS A 1 73  ? 27.266  -10.048 53.421  1 22.885 ? 65   LYS A O   1 
ATOM   319  C  CB  . LYS A 1 73  ? 29.726  -8.251  52.966  1 36.023 ? 65   LYS A CB  1 
ATOM   320  C  CG  . LYS A 1 73  ? 30.599  -8.227  51.686  1 46.241 ? 65   LYS A CG  1 
ATOM   321  C  CD  . LYS A 1 73  ? 30.637  -9.554  50.931  1 49.354 ? 65   LYS A CD  1 
ATOM   322  C  CE  . LYS A 1 73  ? 31.728  -9.716  49.92   1 56.661 ? 65   LYS A CE  1 
ATOM   323  N  NZ  . LYS A 1 73  ? 33.048  -9.836  50.541  1 61.649 ? 65   LYS A NZ  1 
ATOM   324  N  N   . GLU A 1 74  ? 26.58   -8.163  54.45   1 23.752 ? 66   GLU A N   1 
ATOM   325  C  CA  . GLU A 1 74  ? 25.733  -8.884  55.402  1 25.877 ? 66   GLU A CA  1 
ATOM   326  C  C   . GLU A 1 74  ? 24.474  -9.404  54.727  1 29.227 ? 66   GLU A C   1 
ATOM   327  O  O   . GLU A 1 74  ? 23.882  -10.357 55.239  1 20.726 ? 66   GLU A O   1 
ATOM   328  C  CB  . GLU A 1 74  ? 25.264  -8.113  56.642  1 27.978 ? 66   GLU A CB  1 
ATOM   329  C  CG  . GLU A 1 74  ? 26.469  -7.621  57.446  1 30.283 ? 66   GLU A CG  1 
ATOM   330  C  CD  . GLU A 1 74  ? 26.974  -6.213  57.137  1 30.688 ? 66   GLU A CD  1 
ATOM   331  O  OE1 . GLU A 1 74  ? 27.111  -5.778  55.981  1 26.489 ? 66   GLU A OE1 1 
ATOM   332  O  OE2 . GLU A 1 74  ? 27.238  -5.495  58.145  1 32.492 ? 66   GLU A OE2 1 
ATOM   333  N  N   . LEU A 1 75  ? 24.125  -8.823  53.559  1 26.32  ? 67   LEU A N   1 
ATOM   334  C  CA  . LEU A 1 75  ? 22.951  -9.341  52.856  1 24.451 ? 67   LEU A CA  1 
ATOM   335  C  C   . LEU A 1 75  ? 23.297  -10.689 52.248  1 23.086 ? 67   LEU A C   1 
ATOM   336  O  O   . LEU A 1 75  ? 24.194  -10.749 51.423  1 26.064 ? 67   LEU A O   1 
ATOM   337  C  CB  . LEU A 1 75  ? 22.361  -8.364  51.82   1 21.672 ? 67   LEU A CB  1 
ATOM   338  C  CG  . LEU A 1 75  ? 21.76   -7.089  52.403  1 21.542 ? 67   LEU A CG  1 
ATOM   339  C  CD1 . LEU A 1 75  ? 21.485  -6.237  51.211  1 21.471 ? 67   LEU A CD1 1 
ATOM   340  C  CD2 . LEU A 1 75  ? 20.457  -7.438  53.076  1 20.572 ? 67   LEU A CD2 1 
ATOM   341  N  N   . HIS A 1 76  ? 22.531  -11.746 52.601  1 20.106 ? 68   HIS A N   1 
ATOM   342  C  CA  . HIS A 1 76  ? 22.708  -13.074 52.032  1 18.451 ? 68   HIS A CA  1 
ATOM   343  C  C   . HIS A 1 76  ? 21.345  -13.743 51.818  1 17.538 ? 68   HIS A C   1 
ATOM   344  O  O   . HIS A 1 76  ? 20.801  -14.449 52.685  1 15.275 ? 68   HIS A O   1 
ATOM   345  C  CB  . HIS A 1 76  ? 23.67   -13.913 52.899  1 21.025 ? 68   HIS A CB  1 
ATOM   346  C  CG  . HIS A 1 76  ? 24.045  -15.275 52.396  1 22.28  ? 68   HIS A CG  1 
ATOM   347  N  ND1 . HIS A 1 76  ? 25.098  -15.408 51.521  1 27.262 ? 68   HIS A ND1 1 
ATOM   348  C  CD2 . HIS A 1 76  ? 23.591  -16.513 52.578  1 21.962 ? 68   HIS A CD2 1 
ATOM   349  C  CE1 . HIS A 1 76  ? 25.289  -16.684 51.247  1 25.116 ? 68   HIS A CE1 1 
ATOM   350  N  NE2 . HIS A 1 76  ? 24.372  -17.367 51.853  1 25.012 ? 68   HIS A NE2 1 
ATOM   351  N  N   . GLY A 1 77  ? 20.804  -13.595 50.589  1 15.827 ? 69   GLY A N   1 
ATOM   352  C  CA  . GLY A 1 77  ? 19.396  -13.969 50.464  1 19.011 ? 69   GLY A CA  1 
ATOM   353  C  C   . GLY A 1 77  ? 18.771  -13.357 49.225  1 17.355 ? 69   GLY A C   1 
ATOM   354  O  O   . GLY A 1 77  ? 19.51   -12.965 48.301  1 16.584 ? 69   GLY A O   1 
ATOM   355  N  N   . THR A 1 78  ? 17.419  -13.362 49.179  1 20.038 ? 70   THR A N   1 
ATOM   356  C  CA  . THR A 1 78  ? 16.776  -12.94  47.941  1 15.99  ? 70   THR A CA  1 
ATOM   357  C  C   . THR A 1 78  ? 15.612  -12.036 48.322  1 15.261 ? 70   THR A C   1 
ATOM   358  O  O   . THR A 1 78  ? 14.827  -12.44  49.198  1 17.447 ? 70   THR A O   1 
ATOM   359  C  CB  . THR A 1 78  ? 16.25   -14.104 47.086  1 14.435 ? 70   THR A CB  1 
ATOM   360  O  OG1 . THR A 1 78  ? 17.229  -15.114 46.951  1 13.427 ? 70   THR A OG1 1 
ATOM   361  C  CG2 . THR A 1 78  ? 15.834  -13.598 45.685  1 14.862 ? 70   THR A CG2 1 
ATOM   362  N  N   . PHE A 1 79  ? 15.518  -10.842 47.68   1 10.816 ? 71   PHE A N   1 
ATOM   363  C  CA  . PHE A 1 79  ? 14.313  -10.016 47.796  1 10.947 ? 71   PHE A CA  1 
ATOM   364  C  C   . PHE A 1 79  ? 13.42   -10.403 46.626  1 13.766 ? 71   PHE A C   1 
ATOM   365  O  O   . PHE A 1 79  ? 13.8    -10.14  45.476  1 13.856 ? 71   PHE A O   1 
ATOM   366  C  CB  . PHE A 1 79  ? 14.712  -8.557  47.686  1 12.73  ? 71   PHE A CB  1 
ATOM   367  C  CG  . PHE A 1 79  ? 13.613  -7.506  47.784  1 11.814 ? 71   PHE A CG  1 
ATOM   368  C  CD1 . PHE A 1 79  ? 12.393  -7.767  48.412  1 12.584 ? 71   PHE A CD1 1 
ATOM   369  C  CD2 . PHE A 1 79  ? 13.864  -6.222  47.322  1 13.223 ? 71   PHE A CD2 1 
ATOM   370  C  CE1 . PHE A 1 79  ? 11.408  -6.771  48.504  1 11.531 ? 71   PHE A CE1 1 
ATOM   371  C  CE2 . PHE A 1 79  ? 12.913  -5.187  47.507  1 14.133 ? 71   PHE A CE2 1 
ATOM   372  C  CZ  . PHE A 1 79  ? 11.66   -5.478  48.062  1 14.038 ? 71   PHE A CZ  1 
ATOM   373  N  N   . TYR A 1 80  ? 12.301  -11.07  46.946  1 13.788 ? 72   TYR A N   1 
ATOM   374  C  CA  . TYR A 1 80  ? 11.335  -11.458 45.942  1 14.296 ? 72   TYR A CA  1 
ATOM   375  C  C   . TYR A 1 80  ? 10.152  -10.517 45.998  1 15.114 ? 72   TYR A C   1 
ATOM   376  O  O   . TYR A 1 80  ? 9.643   -10.244 47.08   1 15.188 ? 72   TYR A O   1 
ATOM   377  C  CB  . TYR A 1 80  ? 10.779  -12.876 46.143  1 10.757 ? 72   TYR A CB  1 
ATOM   378  C  CG  . TYR A 1 80  ? 11.723  -14.03  45.915  1 11.476 ? 72   TYR A CG  1 
ATOM   379  C  CD1 . TYR A 1 80  ? 11.952  -14.548 44.628  1 10.738 ? 72   TYR A CD1 1 
ATOM   380  C  CD2 . TYR A 1 80  ? 12.364  -14.623 46.975  1 11.858 ? 72   TYR A CD2 1 
ATOM   381  C  CE1 . TYR A 1 80  ? 12.829  -15.621 44.464  1 12.462 ? 72   TYR A CE1 1 
ATOM   382  C  CE2 . TYR A 1 80  ? 13.267  -15.652 46.831  1 12.788 ? 72   TYR A CE2 1 
ATOM   383  C  CZ  . TYR A 1 80  ? 13.503  -16.174 45.565  1 16.056 ? 72   TYR A CZ  1 
ATOM   384  O  OH  . TYR A 1 80  ? 14.347  -17.281 45.431  1 15.807 ? 72   TYR A OH  1 
ATOM   385  N  N   . ARG A 1 81  ? 9.716   -10.036 44.816  1 11.129 ? 73   ARG A N   1 
ATOM   386  C  CA  . ARG A 1 81  ? 8.654   -9.045  44.84   1 11.838 ? 73   ARG A CA  1 
ATOM   387  C  C   . ARG A 1 81  ? 7.652   -9.498  43.826  1 12.993 ? 73   ARG A C   1 
ATOM   388  O  O   . ARG A 1 81  ? 8.101   -10.081 42.822  1 17.92  ? 73   ARG A O   1 
ATOM   389  C  CB  . ARG A 1 81  ? 9.289   -7.728  44.413  1 16.372 ? 73   ARG A CB  1 
ATOM   390  C  CG  . ARG A 1 81  ? 8.361   -6.553  44.658  1 19.671 ? 73   ARG A CG  1 
ATOM   391  C  CD  . ARG A 1 81  ? 8.578   -5.761  45.914  1 15.321 ? 73   ARG A CD  1 
ATOM   392  N  NE  . ARG A 1 81  ? 7.706   -4.639  45.518  1 14.703 ? 73   ARG A NE  1 
ATOM   393  C  CZ  . ARG A 1 81  ? 6.584   -4.349  46.141  1 12.445 ? 73   ARG A CZ  1 
ATOM   394  N  NH1 . ARG A 1 81  ? 6.354   -4.879  47.354  1 13.334 ? 73   ARG A NH1 1 
ATOM   395  N  NH2 . ARG A 1 81  ? 5.711   -3.536  45.584  1 11.803 ? 73   ARG A NH2 1 
ATOM   396  N  N   . ILE A 1 82  ? 6.343   -9.263  44.072  1 12.011 ? 74   ILE A N   1 
ATOM   397  C  CA  . ILE A 1 82  ? 5.395   -9.799  43.1    1 13.246 ? 74   ILE A CA  1 
ATOM   398  C  C   . ILE A 1 82  ? 4.532   -8.653  42.625  1 12.42  ? 74   ILE A C   1 
ATOM   399  O  O   . ILE A 1 82  ? 4.162   -7.788  43.4    1 13.077 ? 74   ILE A O   1 
ATOM   400  C  CB  . ILE A 1 82  ? 4.629   -11.035 43.625  1 12.396 ? 74   ILE A CB  1 
ATOM   401  C  CG1 . ILE A 1 82  ? 3.848   -11.706 42.522  1 12.286 ? 74   ILE A CG1 1 
ATOM   402  C  CG2 . ILE A 1 82  ? 3.785   -10.713 44.877  1 11.345 ? 74   ILE A CG2 1 
ATOM   403  C  CD1 . ILE A 1 82  ? 3.428   -13.138 42.836  1 11.732 ? 74   ILE A CD1 1 
ATOM   404  N  N   . MET A 1 83  ? 4.273   -8.633  41.315  1 13.579 ? 75   MET A N   1 
ATOM   405  C  CA  . MET A 1 83  ? 3.506   -7.539  40.753  1 13.86  ? 75   MET A CA  1 
ATOM   406  C  C   . MET A 1 83  ? 2.352   -8.056  39.89   1 13.57  ? 75   MET A C   1 
ATOM   407  O  O   . MET A 1 83  ? 2.481   -9.132  39.304  1 12.166 ? 75   MET A O   1 
ATOM   408  C  CB  . MET A 1 83  ? 4.4     -6.686  39.845  1 13.067 ? 75   MET A CB  1 
ATOM   409  C  CG  . MET A 1 83  ? 5.526   -5.996  40.58   1 16.008 ? 75   MET A CG  1 
ATOM   410  S  SD  . MET A 1 83  ? 7.121   -6.108  39.744  1 22.357 ? 75   MET A SD  1 
ATOM   411  C  CE  . MET A 1 83  ? 7.369   -7.831  40.056  1 20.378 ? 75   MET A CE  1 
ATOM   412  N  N   . PRO A 1 84  ? 1.253   -7.255  39.683  1 13.815 ? 76   PRO A N   1 
ATOM   413  C  CA  . PRO A 1 84  ? 0.284   -7.557  38.69   1 10.762 ? 76   PRO A CA  1 
ATOM   414  C  C   . PRO A 1 84  ? 0.698   -6.957  37.351  1 11.694 ? 76   PRO A C   1 
ATOM   415  O  O   . PRO A 1 84  ? 1.012   -5.773  37.29   1 11.886 ? 76   PRO A O   1 
ATOM   416  C  CB  . PRO A 1 84  ? -0.978  -6.913  39.277  1 12.335 ? 76   PRO A CB  1 
ATOM   417  C  CG  . PRO A 1 84  ? -0.438  -5.587  39.808  1 13.708 ? 76   PRO A CG  1 
ATOM   418  C  CD  . PRO A 1 84  ? 0.963   -5.972  40.366  1 14.511 ? 76   PRO A CD  1 
ATOM   419  N  N   . ASP A 1 85  ? 0.673   -7.732  36.27   1 11.334 ? 77   ASP A N   1 
ATOM   420  C  CA  . ASP A 1 85  ? 1.187   -7.139  35.046  1 14.101 ? 77   ASP A CA  1 
ATOM   421  C  C   . ASP A 1 85  ? 0.56    -7.949  33.918  1 15.262 ? 77   ASP A C   1 
ATOM   422  O  O   . ASP A 1 85  ? 1.145   -8.913  33.46   1 16.679 ? 77   ASP A O   1 
ATOM   423  C  CB  . ASP A 1 85  ? 2.715   -7.27   34.986  1 13.482 ? 77   ASP A CB  1 
ATOM   424  C  CG  . ASP A 1 85  ? 3.487   -6.45   33.951  1 15.995 ? 77   ASP A CG  1 
ATOM   425  O  OD1 . ASP A 1 85  ? 2.916   -5.498  33.327  1 14.286 ? 77   ASP A OD1 1 
ATOM   426  O  OD2 . ASP A 1 85  ? 4.702   -6.725  33.822  1 18.038 ? 77   ASP A OD2 1 
ATOM   427  N  N   . TYR A 1 86  ? -0.694  -7.671  33.604  1 15.732 ? 78   TYR A N   1 
ATOM   428  C  CA  . TYR A 1 86  ? -1.405  -8.468  32.605  1 17.482 ? 78   TYR A CA  1 
ATOM   429  C  C   . TYR A 1 86  ? -0.512  -8.796  31.393  1 17.42  ? 78   TYR A C   1 
ATOM   430  O  O   . TYR A 1 86  ? 0.101   -7.904  30.848  1 15.481 ? 78   TYR A O   1 
ATOM   431  C  CB  . TYR A 1 86  ? -2.558  -7.596  32.09   1 20.331 ? 78   TYR A CB  1 
ATOM   432  C  CG  . TYR A 1 86  ? -3.903  -7.774  32.774  1 17.033 ? 78   TYR A CG  1 
ATOM   433  C  CD1 . TYR A 1 86  ? -4.495  -9.031  32.847  1 14.665 ? 78   TYR A CD1 1 
ATOM   434  C  CD2 . TYR A 1 86  ? -4.543  -6.694  33.399  1 16.31  ? 78   TYR A CD2 1 
ATOM   435  C  CE1 . TYR A 1 86  ? -5.736  -9.231  33.428  1 13.582 ? 78   TYR A CE1 1 
ATOM   436  C  CE2 . TYR A 1 86  ? -5.778  -6.875  34.019  1 17.55  ? 78   TYR A CE2 1 
ATOM   437  C  CZ  . TYR A 1 86  ? -6.377  -8.131  33.988  1 16.982 ? 78   TYR A CZ  1 
ATOM   438  O  OH  . TYR A 1 86  ? -7.608  -8.262  34.52   1 15.901 ? 78   TYR A OH  1 
ATOM   439  N  N   . ALA A 1 87  ? -0.397  -10.095 31.036  1 12.675 ? 79   ALA A N   1 
ATOM   440  C  CA  . ALA A 1 87  ? 0.505   -10.575 30.002  1 11.01  ? 79   ALA A CA  1 
ATOM   441  C  C   . ALA A 1 87  ? -0.114  -10.322 28.626  1 11.418 ? 79   ALA A C   1 
ATOM   442  O  O   . ALA A 1 87  ? 0.616   -10.091 27.656  1 11.808 ? 79   ALA A O   1 
ATOM   443  C  CB  . ALA A 1 87  ? 0.809   -12.06  30.184  1 8.626  ? 79   ALA A CB  1 
ATOM   444  N  N   . GLN A 1 88  ? -1.452  -10.357 28.555  1 12.833 ? 80   GLN A N   1 
ATOM   445  C  CA  . GLN A 1 88  ? -2.225  -10.126 27.308  1 16.503 ? 80   GLN A CA  1 
ATOM   446  C  C   . GLN A 1 88  ? -3.162  -8.944  27.616  1 13.608 ? 80   GLN A C   1 
ATOM   447  O  O   . GLN A 1 88  ? -3.485  -8.753  28.789  1 14.1   ? 80   GLN A O   1 
ATOM   448  C  CB  . GLN A 1 88  ? -3.043  -11.357 26.865  1 13.94  ? 80   GLN A CB  1 
ATOM   449  C  CG  . GLN A 1 88  ? -2.209  -12.615 26.53   1 11.359 ? 80   GLN A CG  1 
ATOM   450  C  CD  . GLN A 1 88  ? -1.214  -12.428 25.389  1 14.048 ? 80   GLN A CD  1 
ATOM   451  O  OE1 . GLN A 1 88  ? -0.01   -12.704 25.52   1 16.307 ? 80   GLN A OE1 1 
ATOM   452  N  NE2 . GLN A 1 88  ? -1.651  -11.861 24.27   1 13.457 ? 80   GLN A NE2 1 
ATOM   453  N  N   . PRO A 1 89  ? -3.529  -8.094  26.622  1 12.489 ? 81   PRO A N   1 
ATOM   454  C  CA  . PRO A 1 89  ? -4.45   -6.992  26.875  1 13.938 ? 81   PRO A CA  1 
ATOM   455  C  C   . PRO A 1 89  ? -5.782  -7.585  27.361  1 14.947 ? 81   PRO A C   1 
ATOM   456  O  O   . PRO A 1 89  ? -6.272  -8.503  26.739  1 16.225 ? 81   PRO A O   1 
ATOM   457  C  CB  . PRO A 1 89  ? -4.615  -6.276  25.509  1 12.611 ? 81   PRO A CB  1 
ATOM   458  C  CG  . PRO A 1 89  ? -4.101  -7.262  24.536  1 12.464 ? 81   PRO A CG  1 
ATOM   459  C  CD  . PRO A 1 89  ? -3.181  -8.25   25.201  1 11.5   ? 81   PRO A CD  1 
ATOM   460  N  N   . PRO A 1 90  ? -6.263  -7.221  28.594  1 15.677 ? 82   PRO A N   1 
ATOM   461  C  CA  . PRO A 1 90  ? -7.356  -7.923  29.272  1 15.094 ? 82   PRO A CA  1 
ATOM   462  C  C   . PRO A 1 90  ? -8.759  -7.624  28.68   1 15.638 ? 82   PRO A C   1 
ATOM   463  O  O   . PRO A 1 90  ? -9.624  -7.148  29.379  1 14.6   ? 82   PRO A O   1 
ATOM   464  C  CB  . PRO A 1 90  ? -7.108  -7.531  30.741  1 13.62  ? 82   PRO A CB  1 
ATOM   465  C  CG  . PRO A 1 90  ? -6.635  -6.077  30.58   1 14.494 ? 82   PRO A CG  1 
ATOM   466  C  CD  . PRO A 1 90  ? -5.658  -6.176  29.435  1 15.36  ? 82   PRO A CD  1 
ATOM   467  N  N   . THR A 1 91  ? -8.955  -7.835  27.372  1 15.551 ? 83   THR A N   1 
ATOM   468  C  CA  . THR A 1 91  ? -10.07  -7.228  26.68   1 14.822 ? 83   THR A CA  1 
ATOM   469  C  C   . THR A 1 91  ? -11.321 -8.121  26.72   1 16.967 ? 83   THR A C   1 
ATOM   470  O  O   . THR A 1 91  ? -12.341 -7.638  26.279  1 20.542 ? 83   THR A O   1 
ATOM   471  C  CB  . THR A 1 91  ? -9.767  -6.913  25.198  1 13.843 ? 83   THR A CB  1 
ATOM   472  O  OG1 . THR A 1 91  ? -9.167  -8.099  24.703  1 16.353 ? 83   THR A OG1 1 
ATOM   473  C  CG2 . THR A 1 91  ? -8.677  -5.882  25.064  1 17.334 ? 83   THR A CG2 1 
ATOM   474  N  N   . TYR A 1 92  ? -11.293 -9.33   27.315  1 13.775 ? 84   TYR A N   1 
ATOM   475  C  CA  . TYR A 1 92  ? -12.395 -10.297 27.211  1 16.779 ? 84   TYR A CA  1 
ATOM   476  C  C   . TYR A 1 92  ? -13.756 -9.692  27.599  1 14.483 ? 84   TYR A C   1 
ATOM   477  O  O   . TYR A 1 92  ? -14.717 -9.736  26.815  1 14.537 ? 84   TYR A O   1 
ATOM   478  C  CB  . TYR A 1 92  ? -12.19  -11.659 27.891  1 13.24  ? 84   TYR A CB  1 
ATOM   479  C  CG  . TYR A 1 92  ? -13.285 -12.614 27.46   1 16.811 ? 84   TYR A CG  1 
ATOM   480  C  CD1 . TYR A 1 92  ? -13.267 -13.168 26.165  1 19.001 ? 84   TYR A CD1 1 
ATOM   481  C  CD2 . TYR A 1 92  ? -14.389 -12.875 28.267  1 24.853 ? 84   TYR A CD2 1 
ATOM   482  C  CE1 . TYR A 1 92  ? -14.281 -14.015 25.722  1 22.007 ? 84   TYR A CE1 1 
ATOM   483  C  CE2 . TYR A 1 92  ? -15.431 -13.687 27.807  1 21.456 ? 84   TYR A CE2 1 
ATOM   484  C  CZ  . TYR A 1 92  ? -15.389 -14.248 26.534  1 22.526 ? 84   TYR A CZ  1 
ATOM   485  O  OH  . TYR A 1 92  ? -16.443 -15.037 26.105  1 19.82  ? 84   TYR A OH  1 
ATOM   486  N  N   . TYR A 1 93  ? -13.88  -9.203  28.842  1 18.157 ? 85   TYR A N   1 
ATOM   487  C  CA  . TYR A 1 93  ? -15.127 -8.601  29.284  1 18.728 ? 85   TYR A CA  1 
ATOM   488  C  C   . TYR A 1 93  ? -15.157 -7.072  29.147  1 20.114 ? 85   TYR A C   1 
ATOM   489  O  O   . TYR A 1 93  ? -14.34  -6.364  29.748  1 22.394 ? 85   TYR A O   1 
ATOM   490  C  CB  . TYR A 1 93  ? -15.337 -9.1    30.71   1 20.236 ? 85   TYR A CB  1 
ATOM   491  C  CG  . TYR A 1 93  ? -16.698 -8.748  31.298  1 20.664 ? 85   TYR A CG  1 
ATOM   492  C  CD1 . TYR A 1 93  ? -17.854 -9.4    30.898  1 22.661 ? 85   TYR A CD1 1 
ATOM   493  C  CD2 . TYR A 1 93  ? -16.803 -7.781  32.289  1 22.425 ? 85   TYR A CD2 1 
ATOM   494  C  CE1 . TYR A 1 93  ? -19.1   -9.085  31.447  1 22.114 ? 85   TYR A CE1 1 
ATOM   495  C  CE2 . TYR A 1 93  ? -18.028 -7.482  32.874  1 22.587 ? 85   TYR A CE2 1 
ATOM   496  C  CZ  . TYR A 1 93  ? -19.176 -8.153  32.475  1 23.106 ? 85   TYR A CZ  1 
ATOM   497  O  OH  . TYR A 1 93  ? -20.374 -7.857  33.139  1 24.288 ? 85   TYR A OH  1 
ATOM   498  N  N   . LYS A 1 94  ? -16.146 -6.56   28.386  1 20.26  ? 86   LYS A N   1 
ATOM   499  C  CA  . LYS A 1 94  ? -16.405 -5.117  28.263  1 18.867 ? 86   LYS A CA  1 
ATOM   500  C  C   . LYS A 1 94  ? -15.124 -4.371  27.843  1 20.759 ? 86   LYS A C   1 
ATOM   501  O  O   . LYS A 1 94  ? -14.783 -3.306  28.402  1 19.189 ? 86   LYS A O   1 
ATOM   502  C  CB  . LYS A 1 94  ? -17.062 -4.492  29.508  1 17.644 ? 86   LYS A CB  1 
ATOM   503  C  CG  . LYS A 1 94  ? -18.431 -4.951  29.933  1 21.042 ? 86   LYS A CG  1 
ATOM   504  C  CD  . LYS A 1 94  ? -18.868 -4.414  31.291  1 28.008 ? 86   LYS A CD  1 
ATOM   505  C  CE  . LYS A 1 94  ? -20.266 -4.671  31.691  1 33.166 ? 86   LYS A CE  1 
ATOM   506  N  NZ  . LYS A 1 94  ? -20.493 -4.001  32.983  1 37.568 ? 86   LYS A NZ  1 
ATOM   507  N  N   . GLY A 1 95  ? -14.342 -5.016  26.951  1 17.938 ? 87   GLY A N   1 
ATOM   508  C  CA  . GLY A 1 95  ? -13.093 -4.508  26.409  1 19.943 ? 87   GLY A CA  1 
ATOM   509  C  C   . GLY A 1 95  ? -12.077 -4.223  27.509  1 19.031 ? 87   GLY A C   1 
ATOM   510  O  O   . GLY A 1 95  ? -11.122 -3.484  27.283  1 21.252 ? 87   GLY A O   1 
ATOM   511  N  N   . GLY A 1 96  ? -12.31  -4.836  28.691  1 18.625 ? 88   GLY A N   1 
ATOM   512  C  CA  . GLY A 1 96  ? -11.39  -4.726  29.812  1 19.627 ? 88   GLY A CA  1 
ATOM   513  C  C   . GLY A 1 96  ? -11.558 -3.391  30.546  1 21.643 ? 88   GLY A C   1 
ATOM   514  O  O   . GLY A 1 96  ? -10.706 -3.036  31.375  1 18.111 ? 88   GLY A O   1 
ATOM   515  N  N   . GLU A 1 97  ? -12.713 -2.689  30.335  1 20.777 ? 89   GLU A N   1 
ATOM   516  C  CA  . GLU A 1 97  ? -12.762 -1.334  30.865  1 21.024 ? 89   GLU A CA  1 
ATOM   517  C  C   . GLU A 1 97  ? -12.946 -1.369  32.379  1 19.075 ? 89   GLU A C   1 
ATOM   518  O  O   . GLU A 1 97  ? -12.704 -0.345  33      1 15.691 ? 89   GLU A O   1 
ATOM   519  C  CB  . GLU A 1 97  ? -13.63  -0.338  30.091  1 33.612 ? 89   GLU A CB  1 
ATOM   520  C  CG  . GLU A 1 97  ? -12.809 0.617   29.213  1 38.143 ? 89   GLU A CG  1 
ATOM   521  C  CD  . GLU A 1 97  ? -13.48  0.986   27.901  1 58.315 ? 89   GLU A CD  1 
ATOM   522  O  OE1 . GLU A 1 97  ? -14.681 1.396   27.854  1 57.051 ? 89   GLU A OE1 1 
ATOM   523  O  OE2 . GLU A 1 97  ? -12.756 0.853   26.889  1 61.898 ? 89   GLU A OE2 1 
ATOM   524  N  N   . LEU A 1 98  ? -13.283 -2.545  32.933  1 15.414 ? 90   LEU A N   1 
ATOM   525  C  CA  . LEU A 1 98  ? -13.462 -2.606  34.387  1 16.069 ? 90   LEU A CA  1 
ATOM   526  C  C   . LEU A 1 98  ? -12.373 -3.406  35.094  1 19.622 ? 90   LEU A C   1 
ATOM   527  O  O   . LEU A 1 98  ? -12.599 -3.844  36.215  1 19.935 ? 90   LEU A O   1 
ATOM   528  C  CB  . LEU A 1 98  ? -14.865 -3.169  34.669  1 16.943 ? 90   LEU A CB  1 
ATOM   529  C  CG  . LEU A 1 98  ? -16.061 -2.256  34.368  1 18.221 ? 90   LEU A CG  1 
ATOM   530  C  CD1 . LEU A 1 98  ? -17.305 -2.993  34.885  1 21.49  ? 90   LEU A CD1 1 
ATOM   531  C  CD2 . LEU A 1 98  ? -15.985 -0.902  35.008  1 22.948 ? 90   LEU A CD2 1 
ATOM   532  N  N   . ASN A 1 99  ? -11.211 -3.633  34.44   1 17.578 ? 91   ASN A N   1 
ATOM   533  C  CA  . ASN A 1 99  ? -10.125 -4.386  35.062  1 17.19  ? 91   ASN A CA  1 
ATOM   534  C  C   . ASN A 1 99  ? -9.708  -3.612  36.317  1 15.799 ? 91   ASN A C   1 
ATOM   535  O  O   . ASN A 1 99  ? -9.739  -2.356  36.313  1 18.522 ? 91   ASN A O   1 
ATOM   536  C  CB  . ASN A 1 99  ? -9.052  -4.715  34.028  1 15.748 ? 91   ASN A CB  1 
ATOM   537  C  CG  . ASN A 1 99  ? -8.077  -3.565  33.824  1 21.094 ? 91   ASN A CG  1 
ATOM   538  O  OD1 . ASN A 1 99  ? -7.253  -3.275  34.704  1 17.994 ? 91   ASN A OD1 1 
ATOM   539  N  ND2 . ASN A 1 99  ? -8.17   -2.871  32.689  1 19.214 ? 91   ASN A ND2 1 
ATOM   540  N  N   . ALA A 1 100 ? -9.402  -4.331  37.41   1 13.119 ? 92   ALA A N   1 
ATOM   541  C  CA  . ALA A 1 100 ? -9.06   -3.704  38.67   1 13.803 ? 92   ALA A CA  1 
ATOM   542  C  C   . ALA A 1 100 ? -7.504  -3.662  38.781  1 14.244 ? 92   ALA A C   1 
ATOM   543  O  O   . ALA A 1 100 ? -6.821  -4.505  38.193  1 14.633 ? 92   ALA A O   1 
ATOM   544  C  CB  . ALA A 1 100 ? -9.682  -4.44   39.859  1 15.099 ? 92   ALA A CB  1 
ATOM   545  N  N   . PRO A 1 101 ? -6.866  -2.702  39.493  1 14.966 ? 93   PRO A N   1 
ATOM   546  C  CA  . PRO A 1 101 ? -5.407  -2.736  39.696  1 15.044 ? 93   PRO A CA  1 
ATOM   547  C  C   . PRO A 1 101 ? -4.835  -4.03   40.303  1 15.082 ? 93   PRO A C   1 
ATOM   548  O  O   . PRO A 1 101 ? -3.668  -4.313  40.087  1 14.672 ? 93   PRO A O   1 
ATOM   549  C  CB  . PRO A 1 101 ? -5.113  -1.517  40.547  1 19.78  ? 93   PRO A CB  1 
ATOM   550  C  CG  . PRO A 1 101 ? -6.466  -1.267  41.267  1 19.896 ? 93   PRO A CG  1 
ATOM   551  C  CD  . PRO A 1 101 ? -7.495  -1.561  40.204  1 15.982 ? 93   PRO A CD  1 
ATOM   552  N  N   . ILE A 1 102 ? -5.692  -4.816  40.982  1 15.52  ? 94   ILE A N   1 
ATOM   553  C  CA  . ILE A 1 102 ? -5.361  -6.051  41.659  1 13.8   ? 94   ILE A CA  1 
ATOM   554  C  C   . ILE A 1 102 ? -5.551  -7.242  40.742  1 13.485 ? 94   ILE A C   1 
ATOM   555  O  O   . ILE A 1 102 ? -5.347  -8.361  41.215  1 14.406 ? 94   ILE A O   1 
ATOM   556  C  CB  . ILE A 1 102 ? -6.061  -6.2    43.02   1 12.47  ? 94   ILE A CB  1 
ATOM   557  C  CG1 . ILE A 1 102 ? -7.625  -6.301  42.853  1 14.373 ? 94   ILE A CG1 1 
ATOM   558  C  CG2 . ILE A 1 102 ? -5.637  -5.089  43.983  1 14.886 ? 94   ILE A CG2 1 
ATOM   559  C  CD1 . ILE A 1 102 ? -8.376  -6.608  44.153  1 15.34  ? 94   ILE A CD1 1 
ATOM   560  N  N   . ASP A 1 103 ? -5.904  -7.031  39.446  1 13.658 ? 95   ASP A N   1 
ATOM   561  C  CA  . ASP A 1 103 ? -6.216  -8.162  38.601  1 14.053 ? 95   ASP A CA  1 
ATOM   562  C  C   . ASP A 1 103 ? -5.025  -8.836  37.916  1 13.312 ? 95   ASP A C   1 
ATOM   563  O  O   . ASP A 1 103 ? -5.117  -10.024 37.632  1 13.714 ? 95   ASP A O   1 
ATOM   564  C  CB  . ASP A 1 103 ? -7.184  -7.877  37.46   1 15.684 ? 95   ASP A CB  1 
ATOM   565  C  CG  . ASP A 1 103 ? -8.652  -8.089  37.784  1 17.973 ? 95   ASP A CG  1 
ATOM   566  O  OD1 . ASP A 1 103 ? -9.002  -9.199  38.241  1 16.581 ? 95   ASP A OD1 1 
ATOM   567  O  OD2 . ASP A 1 103 ? -9.415  -7.134  37.575  1 18.607 ? 95   ASP A OD2 1 
ATOM   568  N  N   . GLY A 1 104 ? -3.996  -8.093  37.522  1 12.866 ? 96   GLY A N   1 
ATOM   569  C  CA  . GLY A 1 104 ? -3.176  -8.597  36.399  1 12.938 ? 96   GLY A CA  1 
ATOM   570  C  C   . GLY A 1 104 ? -2.335  -9.833  36.776  1 11.412 ? 96   GLY A C   1 
ATOM   571  O  O   . GLY A 1 104 ? -2.069  -10.074 37.967  1 11.289 ? 96   GLY A O   1 
ATOM   572  N  N   . ASP A 1 105 ? -2.007  -10.634 35.756  1 11.117 ? 97   ASP A N   1 
ATOM   573  C  CA  . ASP A 1 105 ? -1.194  -11.852 35.873  1 13.189 ? 97   ASP A CA  1 
ATOM   574  C  C   . ASP A 1 105 ? 0.037   -11.612 36.739  1 12.507 ? 97   ASP A C   1 
ATOM   575  O  O   . ASP A 1 105 ? 0.735   -10.596 36.569  1 10.727 ? 97   ASP A O   1 
ATOM   576  C  CB  . ASP A 1 105 ? -0.683  -12.245 34.496  1 13.196 ? 97   ASP A CB  1 
ATOM   577  C  CG  . ASP A 1 105 ? -1.821  -12.592 33.582  1 16.478 ? 97   ASP A CG  1 
ATOM   578  O  OD1 . ASP A 1 105 ? -2.559  -13.548 33.994  1 13.212 ? 97   ASP A OD1 1 
ATOM   579  O  OD2 . ASP A 1 105 ? -1.956  -11.931 32.47   1 14.53  ? 97   ASP A OD2 1 
ATOM   580  N  N   . GLY A 1 106 ? 0.226   -12.463 37.752  1 13.059 ? 98   GLY A N   1 
ATOM   581  C  CA  . GLY A 1 106 ? 1.373   -12.336 38.633  1 13.037 ? 98   GLY A CA  1 
ATOM   582  C  C   . GLY A 1 106 ? 2.752   -12.52  37.999  1 11.615 ? 98   GLY A C   1 
ATOM   583  O  O   . GLY A 1 106 ? 2.99    -13.461 37.259  1 12.972 ? 98   GLY A O   1 
ATOM   584  N  N   . THR A 1 107 ? 3.661   -11.568 38.264  1 10.763 ? 99   THR A N   1 
ATOM   585  C  CA  . THR A 1 107 ? 5.034   -11.744 37.814  1 13.163 ? 99   THR A CA  1 
ATOM   586  C  C   . THR A 1 107 ? 5.945   -11.497 39.013  1 13.517 ? 99   THR A C   1 
ATOM   587  O  O   . THR A 1 107 ? 5.65    -10.593 39.777  1 15.923 ? 99   THR A O   1 
ATOM   588  C  CB  . THR A 1 107 ? 5.291   -10.856 36.601  1 11.885 ? 99   THR A CB  1 
ATOM   589  O  OG1 . THR A 1 107 ? 6.646   -11.068 36.233  1 15.375 ? 99   THR A OG1 1 
ATOM   590  C  CG2 . THR A 1 107 ? 5.006   -9.375  36.836  1 11.044 ? 99   THR A CG2 1 
ATOM   591  N  N   . VAL A 1 108 ? 7.009   -12.305 39.154  1 12.638 ? 100  VAL A N   1 
ATOM   592  C  CA  . VAL A 1 108 ? 7.877   -12.286 40.332  1 12.459 ? 100  VAL A CA  1 
ATOM   593  C  C   . VAL A 1 108 ? 9.199   -11.684 39.892  1 12.623 ? 100  VAL A C   1 
ATOM   594  O  O   . VAL A 1 108 ? 9.715   -12.14  38.867  1 12.656 ? 100  VAL A O   1 
ATOM   595  C  CB  . VAL A 1 108 ? 8.107   -13.664 40.993  1 12.541 ? 100  VAL A CB  1 
ATOM   596  C  CG1 . VAL A 1 108 ? 9.171   -13.652 42.112  1 15.505 ? 100  VAL A CG1 1 
ATOM   597  C  CG2 . VAL A 1 108 ? 6.798   -14.242 41.474  1 11.773 ? 100  VAL A CG2 1 
ATOM   598  N  N   . ALA A 1 109 ? 9.656   -10.655 40.595  1 11.163 ? 101  ALA A N   1 
ATOM   599  C  CA  . ALA A 1 109 ? 10.995  -10.09  40.371  1 12.346 ? 101  ALA A CA  1 
ATOM   600  C  C   . ALA A 1 109 ? 11.881  -10.64  41.481  1 13.456 ? 101  ALA A C   1 
ATOM   601  O  O   . ALA A 1 109 ? 11.489  -10.493 42.64   1 16.078 ? 101  ALA A O   1 
ATOM   602  C  CB  . ALA A 1 109 ? 10.978  -8.564  40.413  1 12.409 ? 101  ALA A CB  1 
ATOM   603  N  N   . ALA A 1 110 ? 13.029  -11.284 41.157  1 13.339 ? 102  ALA A N   1 
ATOM   604  C  CA  . ALA A 1 110 ? 13.867  -11.722 42.273  1 11.542 ? 102  ALA A CA  1 
ATOM   605  C  C   . ALA A 1 110 ? 15.182  -10.935 42.225  1 14.087 ? 102  ALA A C   1 
ATOM   606  O  O   . ALA A 1 110 ? 15.73   -10.72  41.143  1 13.912 ? 102  ALA A O   1 
ATOM   607  C  CB  . ALA A 1 110 ? 14.155  -13.196 42.139  1 10.717 ? 102  ALA A CB  1 
ATOM   608  N  N   . PHE A 1 111 ? 15.646  -10.46  43.398  1 11.687 ? 103  PHE A N   1 
ATOM   609  C  CA  . PHE A 1 111 ? 16.92   -9.754  43.473  1 13.394 ? 103  PHE A CA  1 
ATOM   610  C  C   . PHE A 1 111 ? 17.799  -10.447 44.505  1 15.998 ? 103  PHE A C   1 
ATOM   611  O  O   . PHE A 1 111 ? 17.578  -10.309 45.731  1 12.772 ? 103  PHE A O   1 
ATOM   612  C  CB  . PHE A 1 111 ? 16.729  -8.298  43.924  1 14.333 ? 103  PHE A CB  1 
ATOM   613  C  CG  . PHE A 1 111 ? 15.877  -7.416  43.015  1 15.594 ? 103  PHE A CG  1 
ATOM   614  C  CD1 . PHE A 1 111 ? 16.441  -6.721  41.94   1 16.978 ? 103  PHE A CD1 1 
ATOM   615  C  CD2 . PHE A 1 111 ? 14.482  -7.322  43.19   1 16.323 ? 103  PHE A CD2 1 
ATOM   616  C  CE1 . PHE A 1 111 ? 15.641  -5.905  41.108  1 15.875 ? 103  PHE A CE1 1 
ATOM   617  C  CE2 . PHE A 1 111 ? 13.71   -6.513  42.374  1 15.107 ? 103  PHE A CE2 1 
ATOM   618  C  CZ  . PHE A 1 111 ? 14.288  -5.813  41.335  1 15.515 ? 103  PHE A CZ  1 
ATOM   619  N  N   . ARG A 1 112 ? 18.782  -11.178 43.991  1 16.444 ? 104  ARG A N   1 
ATOM   620  C  CA  . ARG A 1 112 ? 19.538  -12.052 44.864  1 20.054 ? 104  ARG A CA  1 
ATOM   621  C  C   . ARG A 1 112 ? 20.895  -11.391 45.212  1 19.2   ? 104  ARG A C   1 
ATOM   622  O  O   . ARG A 1 112 ? 21.629  -10.956 44.327  1 16.868 ? 104  ARG A O   1 
ATOM   623  C  CB  . ARG A 1 112 ? 19.629  -13.419 44.214  1 15.347 ? 104  ARG A CB  1 
ATOM   624  C  CG  . ARG A 1 112 ? 20.389  -14.293 45.208  1 19.006 ? 104  ARG A CG  1 
ATOM   625  C  CD  . ARG A 1 112 ? 20.382  -15.756 44.752  1 17.062 ? 104  ARG A CD  1 
ATOM   626  N  NE  . ARG A 1 112 ? 19.059  -16.31  45.02   1 16.158 ? 104  ARG A NE  1 
ATOM   627  C  CZ  . ARG A 1 112 ? 18.563  -17.486 44.621  1 15.175 ? 104  ARG A CZ  1 
ATOM   628  N  NH1 . ARG A 1 112 ? 19.364  -18.403 44.089  1 17.399 ? 104  ARG A NH1 1 
ATOM   629  N  NH2 . ARG A 1 112 ? 17.263  -17.754 44.817  1 16.971 ? 104  ARG A NH2 1 
ATOM   630  N  N   . PHE A 1 113 ? 21.145  -11.312 46.525  1 14.028 ? 105  PHE A N   1 
ATOM   631  C  CA  . PHE A 1 113 ? 22.252  -10.659 47.168  1 18.374 ? 105  PHE A CA  1 
ATOM   632  C  C   . PHE A 1 113 ? 23.144  -11.759 47.769  1 21.613 ? 105  PHE A C   1 
ATOM   633  O  O   . PHE A 1 113 ? 22.761  -12.496 48.652  1 24.285 ? 105  PHE A O   1 
ATOM   634  C  CB  . PHE A 1 113 ? 21.753  -9.663  48.219  1 17.079 ? 105  PHE A CB  1 
ATOM   635  C  CG  . PHE A 1 113 ? 20.967  -8.429  47.782  1 17.193 ? 105  PHE A CG  1 
ATOM   636  C  CD1 . PHE A 1 113 ? 19.599  -8.553  47.459  1 16.747 ? 105  PHE A CD1 1 
ATOM   637  C  CD2 . PHE A 1 113 ? 21.566  -7.171  47.695  1 15.341 ? 105  PHE A CD2 1 
ATOM   638  C  CE1 . PHE A 1 113 ? 18.856  -7.452  47.077  1 16.607 ? 105  PHE A CE1 1 
ATOM   639  C  CE2 . PHE A 1 113 ? 20.834  -6.058  47.287  1 17.699 ? 105  PHE A CE2 1 
ATOM   640  C  CZ  . PHE A 1 113 ? 19.477  -6.195  46.985  1 18.432 ? 105  PHE A CZ  1 
ATOM   641  N  N   . LYS A 1 114 ? 24.326  -11.907 47.202  1 20.409 ? 106  LYS A N   1 
ATOM   642  C  CA  . LYS A 1 114 ? 25.312  -12.895 47.599  1 22.829 ? 106  LYS A CA  1 
ATOM   643  C  C   . LYS A 1 114 ? 26.685  -12.251 47.466  1 27.743 ? 106  LYS A C   1 
ATOM   644  O  O   . LYS A 1 114 ? 27.102  -11.874 46.374  1 20.763 ? 106  LYS A O   1 
ATOM   645  C  CB  . LYS A 1 114 ? 25.104  -14.289 47.012  1 24.518 ? 106  LYS A CB  1 
ATOM   646  C  CG  . LYS A 1 114 ? 26.063  -15.373 47.477  1 29.479 ? 106  LYS A CG  1 
ATOM   647  C  CD  . LYS A 1 114 ? 25.591  -16.759 47.1    1 31.733 ? 106  LYS A CD  1 
ATOM   648  C  CE  . LYS A 1 114 ? 26.74   -17.707 47.326  1 30.421 ? 106  LYS A CE  1 
ATOM   649  N  NZ  . LYS A 1 114 ? 26.003  -18.932 47.071  1 39.106 ? 106  LYS A NZ  1 
ATOM   650  N  N   . ASP A 1 115 ? 27.34   -12.094 48.62   1 27.635 ? 107  ASP A N   1 
ATOM   651  C  CA  . ASP A 1 115 ? 28.713  -11.61  48.649  1 28.83  ? 107  ASP A CA  1 
ATOM   652  C  C   . ASP A 1 115 ? 28.82   -10.247 47.957  1 30.231 ? 107  ASP A C   1 
ATOM   653  O  O   . ASP A 1 115 ? 29.795  -9.976  47.236  1 32.48  ? 107  ASP A O   1 
ATOM   654  C  CB  . ASP A 1 115 ? 29.706  -12.606 48.06   1 28.331 ? 107  ASP A CB  1 
ATOM   655  C  CG  . ASP A 1 115 ? 29.812  -13.973 48.705  1 31.371 ? 107  ASP A CG  1 
ATOM   656  O  OD1 . ASP A 1 115 ? 29.798  -14.038 49.928  1 32.616 ? 107  ASP A OD1 1 
ATOM   657  O  OD2 . ASP A 1 115 ? 29.977  -14.95  47.971  1 33.548 ? 107  ASP A OD2 1 
ATOM   658  N  N   . GLY A 1 116 ? 27.823  -9.39   48.183  1 23.425 ? 108  GLY A N   1 
ATOM   659  C  CA  . GLY A 1 116 ? 27.812  -8.047  47.674  1 20.464 ? 108  GLY A CA  1 
ATOM   660  C  C   . GLY A 1 116 ? 27.464  -7.965  46.173  1 18.811 ? 108  GLY A C   1 
ATOM   661  O  O   . GLY A 1 116 ? 27.363  -6.863  45.669  1 22.219 ? 108  GLY A O   1 
ATOM   662  N  N   . LYS A 1 117 ? 27.304  -9.077  45.468  1 19.413 ? 109  LYS A N   1 
ATOM   663  C  CA  . LYS A 1 117 ? 26.813  -9.018  44.08   1 18.523 ? 109  LYS A CA  1 
ATOM   664  C  C   . LYS A 1 117 ? 25.285  -9.15   44.11   1 18.137 ? 109  LYS A C   1 
ATOM   665  O  O   . LYS A 1 117 ? 24.773  -9.914  44.933  1 19.041 ? 109  LYS A O   1 
ATOM   666  C  CB  . LYS A 1 117 ? 27.321  -10.174 43.208  1 18.547 ? 109  LYS A CB  1 
ATOM   667  C  CG  . LYS A 1 117 ? 26.86   -10.186 41.694  1 23.112 ? 109  LYS A CG  1 
ATOM   668  C  CD  . LYS A 1 117 ? 27.201  -11.072 40.478  1 19.97  ? 109  LYS A CD  1 
ATOM   669  C  CE  . LYS A 1 117 ? 27.53   -12.498 40.677  1 23.501 ? 109  LYS A CE  1 
ATOM   670  N  NZ  . LYS A 1 117 ? 26.32   -13.287 40.899  1 24.276 ? 109  LYS A NZ  1 
ATOM   671  N  N   . VAL A 1 118 ? 24.601  -8.587  43.088  1 15.298 ? 110  VAL A N   1 
ATOM   672  C  CA  . VAL A 1 118 ? 23.143  -8.581  43.034  1 13.638 ? 110  VAL A CA  1 
ATOM   673  C  C   . VAL A 1 118 ? 22.769  -9.055  41.635  1 14.766 ? 110  VAL A C   1 
ATOM   674  O  O   . VAL A 1 118 ? 23.226  -8.431  40.66   1 11.339 ? 110  VAL A O   1 
ATOM   675  C  CB  . VAL A 1 118 ? 22.481  -7.22   43.296  1 17.437 ? 110  VAL A CB  1 
ATOM   676  C  CG1 . VAL A 1 118 ? 20.955  -7.336  43.274  1 18     ? 110  VAL A CG1 1 
ATOM   677  C  CG2 . VAL A 1 118 ? 22.956  -6.589  44.616  1 19.209 ? 110  VAL A CG2 1 
ATOM   678  N  N   . ASP A 1 119 ? 21.908  -10.09  41.57   1 15.227 ? 111  ASP A N   1 
ATOM   679  C  CA  . ASP A 1 119 ? 21.388  -10.479 40.254  1 12.851 ? 111  ASP A CA  1 
ATOM   680  C  C   . ASP A 1 119 ? 19.872  -10.366 40.287  1 14.332 ? 111  ASP A C   1 
ATOM   681  O  O   . ASP A 1 119 ? 19.269  -10.348 41.366  1 14.476 ? 111  ASP A O   1 
ATOM   682  C  CB  . ASP A 1 119 ? 21.708  -11.936 39.948  1 12.245 ? 111  ASP A CB  1 
ATOM   683  C  CG  . ASP A 1 119 ? 23.175  -12.335 39.824  1 12.284 ? 111  ASP A CG  1 
ATOM   684  O  OD1 . ASP A 1 119 ? 23.978  -11.484 39.485  1 15.78  ? 111  ASP A OD1 1 
ATOM   685  O  OD2 . ASP A 1 119 ? 23.495  -13.511 40.054  1 16.969 ? 111  ASP A OD2 1 
ATOM   686  N  N   . TYR A 1 120 ? 19.268  -10.342 39.072  1 12.286 ? 112  TYR A N   1 
ATOM   687  C  CA  . TYR A 1 120 ? 17.846  -10.129 39.01   1 13.467 ? 112  TYR A CA  1 
ATOM   688  C  C   . TYR A 1 120 ? 17.308  -11.121 38      1 12.416 ? 112  TYR A C   1 
ATOM   689  O  O   . TYR A 1 120 ? 17.901  -11.254 36.926  1 15.782 ? 112  TYR A O   1 
ATOM   690  C  CB  . TYR A 1 120 ? 17.614  -8.693  38.484  1 15.14  ? 112  TYR A CB  1 
ATOM   691  C  CG  . TYR A 1 120 ? 16.319  -8.355  37.754  1 15.828 ? 112  TYR A CG  1 
ATOM   692  C  CD1 . TYR A 1 120 ? 15.147  -8.081  38.466  1 17.684 ? 112  TYR A CD1 1 
ATOM   693  C  CD2 . TYR A 1 120 ? 16.285  -8.369  36.333  1 17.5   ? 112  TYR A CD2 1 
ATOM   694  C  CE1 . TYR A 1 120 ? 13.954  -7.782  37.807  1 19.002 ? 112  TYR A CE1 1 
ATOM   695  C  CE2 . TYR A 1 120 ? 15.086  -8.061  35.68   1 16.256 ? 112  TYR A CE2 1 
ATOM   696  C  CZ  . TYR A 1 120 ? 13.952  -7.779  36.416  1 20.627 ? 112  TYR A CZ  1 
ATOM   697  O  OH  . TYR A 1 120 ? 12.788  -7.436  35.816  1 22.432 ? 112  TYR A OH  1 
ATOM   698  N  N   . ARG A 1 121 ? 16.084  -11.6   38.316  1 13.075 ? 113  ARG A N   1 
ATOM   699  C  CA  . ARG A 1 121 ? 15.261  -12.417 37.456  1 11.909 ? 113  ARG A CA  1 
ATOM   700  C  C   . ARG A 1 121 ? 13.778  -11.979 37.61   1 12.619 ? 113  ARG A C   1 
ATOM   701  O  O   . ARG A 1 121 ? 13.295  -11.704 38.719  1 10.379 ? 113  ARG A O   1 
ATOM   702  C  CB  . ARG A 1 121 ? 15.423  -13.929 37.641  1 11.228 ? 113  ARG A CB  1 
ATOM   703  C  CG  . ARG A 1 121 ? 14.546  -14.821 36.779  1 11.715 ? 113  ARG A CG  1 
ATOM   704  C  CD  . ARG A 1 121 ? 14.822  -16.307 37.075  1 9.396  ? 113  ARG A CD  1 
ATOM   705  N  NE  . ARG A 1 121 ? 16.042  -16.875 36.494  1 12.302 ? 113  ARG A NE  1 
ATOM   706  C  CZ  . ARG A 1 121 ? 16.198  -17.29  35.215  1 15.543 ? 113  ARG A CZ  1 
ATOM   707  N  NH1 . ARG A 1 121 ? 15.289  -17.064 34.249  1 11.329 ? 113  ARG A NH1 1 
ATOM   708  N  NH2 . ARG A 1 121 ? 17.331  -17.866 34.887  1 14.906 ? 113  ARG A NH2 1 
ATOM   709  N  N   . GLN A 1 122 ? 13.119  -11.827 36.451  1 8.617  ? 114  GLN A N   1 
ATOM   710  C  CA  . GLN A 1 122 ? 11.681  -11.685 36.459  1 12.42  ? 114  GLN A CA  1 
ATOM   711  C  C   . GLN A 1 122 ? 11.027  -12.791 35.633  1 12.613 ? 114  GLN A C   1 
ATOM   712  O  O   . GLN A 1 122 ? 11.506  -13.093 34.527  1 14.72  ? 114  GLN A O   1 
ATOM   713  C  CB  . GLN A 1 122 ? 11.362  -10.287 35.915  1 13.94  ? 114  GLN A CB  1 
ATOM   714  C  CG  . GLN A 1 122 ? 9.853   -10.047 35.941  1 15.71  ? 114  GLN A CG  1 
ATOM   715  C  CD  . GLN A 1 122 ? 9.528   -8.674  36.457  1 20.089 ? 114  GLN A CD  1 
ATOM   716  O  OE1 . GLN A 1 122 ? 10.409  -7.854  36.744  1 22.22  ? 114  GLN A OE1 1 
ATOM   717  N  NE2 . GLN A 1 122 ? 8.248   -8.379  36.533  1 27.037 ? 114  GLN A NE2 1 
ATOM   718  N  N   . ARG A 1 123 ? 9.895   -13.34  36.157  1 11.597 ? 115  ARG A N   1 
ATOM   719  C  CA  . ARG A 1 123 ? 9.181   -14.347 35.416  1 11.644 ? 115  ARG A CA  1 
ATOM   720  C  C   . ARG A 1 123 ? 7.692   -14.345 35.835  1 13.232 ? 115  ARG A C   1 
ATOM   721  O  O   . ARG A 1 123 ? 7.358   -14.156 37.046  1 10.712 ? 115  ARG A O   1 
ATOM   722  C  CB  . ARG A 1 123 ? 9.657   -15.788 35.598  1 10.886 ? 115  ARG A CB  1 
ATOM   723  C  CG  . ARG A 1 123 ? 9.303   -16.697 34.418  1 12.905 ? 115  ARG A CG  1 
ATOM   724  C  CD  . ARG A 1 123 ? 10.219  -17.898 34.731  1 14.726 ? 115  ARG A CD  1 
ATOM   725  N  NE  . ARG A 1 123 ? 9.994   -18.881 33.676  1 15.164 ? 115  ARG A NE  1 
ATOM   726  C  CZ  . ARG A 1 123 ? 10.695  -20.01  33.419  1 19.959 ? 115  ARG A CZ  1 
ATOM   727  N  NH1 . ARG A 1 123 ? 11.729  -20.378 34.151  1 21.149 ? 115  ARG A NH1 1 
ATOM   728  N  NH2 . ARG A 1 123 ? 10.417  -20.739 32.335  1 23.741 ? 115  ARG A NH2 1 
ATOM   729  N  N   . PHE A 1 124 ? 6.839   -14.515 34.826  1 13.664 ? 116  PHE A N   1 
ATOM   730  C  CA  . PHE A 1 124 ? 5.402   -14.696 35.111  1 13.521 ? 116  PHE A CA  1 
ATOM   731  C  C   . PHE A 1 124 ? 5.131   -16.047 35.762  1 14.022 ? 116  PHE A C   1 
ATOM   732  O  O   . PHE A 1 124 ? 5.806   -17.035 35.446  1 13.945 ? 116  PHE A O   1 
ATOM   733  C  CB  . PHE A 1 124 ? 4.566   -14.733 33.835  1 13.995 ? 116  PHE A CB  1 
ATOM   734  C  CG  . PHE A 1 124 ? 4.274   -13.344 33.292  1 13.175 ? 116  PHE A CG  1 
ATOM   735  C  CD1 . PHE A 1 124 ? 3.363   -12.534 33.964  1 12.571 ? 116  PHE A CD1 1 
ATOM   736  C  CD2 . PHE A 1 124 ? 4.827   -12.93  32.077  1 13.787 ? 116  PHE A CD2 1 
ATOM   737  C  CE1 . PHE A 1 124 ? 3.096   -11.245 33.544  1 13.628 ? 116  PHE A CE1 1 
ATOM   738  C  CE2 . PHE A 1 124 ? 4.508   -11.656 31.597  1 16.716 ? 116  PHE A CE2 1 
ATOM   739  C  CZ  . PHE A 1 124 ? 3.588   -10.84  32.296  1 14.719 ? 116  PHE A CZ  1 
ATOM   740  N  N   . VAL A 1 125 ? 4.206   -16.028 36.746  1 13.898 ? 117  VAL A N   1 
ATOM   741  C  CA  . VAL A 1 125 ? 3.658   -17.239 37.325  1 13.477 ? 117  VAL A CA  1 
ATOM   742  C  C   . VAL A 1 125 ? 2.841   -17.931 36.22   1 13.919 ? 117  VAL A C   1 
ATOM   743  O  O   . VAL A 1 125 ? 1.974   -17.332 35.589  1 14.688 ? 117  VAL A O   1 
ATOM   744  C  CB  . VAL A 1 125 ? 2.823   -17.048 38.6    1 12.302 ? 117  VAL A CB  1 
ATOM   745  C  CG1 . VAL A 1 125 ? 2.383   -18.38  39.184  1 10.509 ? 117  VAL A CG1 1 
ATOM   746  C  CG2 . VAL A 1 125 ? 3.617   -16.267 39.646  1 9.925  ? 117  VAL A CG2 1 
ATOM   747  N  N   . GLU A 1 126 ? 3.138   -19.208 35.965  1 12.994 ? 118  GLU A N   1 
ATOM   748  C  CA  . GLU A 1 126 ? 2.395   -19.967 34.972  1 13.357 ? 118  GLU A CA  1 
ATOM   749  C  C   . GLU A 1 126 ? 1.119   -20.504 35.586  1 13.429 ? 118  GLU A C   1 
ATOM   750  O  O   . GLU A 1 126 ? 0.897   -21.706 35.607  1 11.24  ? 118  GLU A O   1 
ATOM   751  C  CB  . GLU A 1 126 ? 3.145   -21.156 34.377  1 18.259 ? 118  GLU A CB  1 
ATOM   752  C  CG  . GLU A 1 126 ? 4.353   -20.818 33.549  1 20.798 ? 118  GLU A CG  1 
ATOM   753  C  CD  . GLU A 1 126 ? 4.683   -22.162 32.847  1 24.75  ? 118  GLU A CD  1 
ATOM   754  O  OE1 . GLU A 1 126 ? 4.194   -23.323 33.011  1 24.056 ? 118  GLU A OE1 1 
ATOM   755  O  OE2 . GLU A 1 126 ? 5.575   -21.972 32.092  1 21.461 ? 118  GLU A OE2 1 
ATOM   756  N  N   . THR A 1 127 ? 0.2     -19.59  35.973  1 13.475 ? 119  THR A N   1 
ATOM   757  C  CA  . THR A 1 127 ? -1.125  -19.986 36.449  1 11.713 ? 119  THR A CA  1 
ATOM   758  C  C   . THR A 1 127 ? -1.89   -20.621 35.296  1 11.2   ? 119  THR A C   1 
ATOM   759  O  O   . THR A 1 127 ? -1.572  -20.4   34.126  1 11.605 ? 119  THR A O   1 
ATOM   760  C  CB  . THR A 1 127 ? -1.889  -18.748 36.958  1 12.311 ? 119  THR A CB  1 
ATOM   761  O  OG1 . THR A 1 127 ? -2.219  -17.945 35.822  1 11.65  ? 119  THR A OG1 1 
ATOM   762  C  CG2 . THR A 1 127 ? -1.097  -17.981 37.987  1 10.946 ? 119  THR A CG2 1 
ATOM   763  N  N   . ASP A 1 128 ? -2.936  -21.398 35.673  1 13.565 ? 120  ASP A N   1 
ATOM   764  C  CA  . ASP A 1 128 ? -3.779  -21.993 34.652  1 14.878 ? 120  ASP A CA  1 
ATOM   765  C  C   . ASP A 1 128 ? -4.329  -20.931 33.715  1 14.487 ? 120  ASP A C   1 
ATOM   766  O  O   . ASP A 1 128 ? -4.385  -21.117 32.48   1 14.884 ? 120  ASP A O   1 
ATOM   767  C  CB  . ASP A 1 128 ? -4.804  -22.93  35.269  1 13.224 ? 120  ASP A CB  1 
ATOM   768  C  CG  . ASP A 1 128 ? -4.229  -24.245 35.783  1 14.313 ? 120  ASP A CG  1 
ATOM   769  O  OD1 . ASP A 1 128 ? -3.053  -24.555 35.435  1 14.955 ? 120  ASP A OD1 1 
ATOM   770  O  OD2 . ASP A 1 128 ? -4.972  -25.04  36.381  1 16.258 ? 120  ASP A OD2 1 
ATOM   771  N  N   . ARG A 1 129 ? -4.738  -19.809 34.335  1 14.441 ? 121  ARG A N   1 
ATOM   772  C  CA  . ARG A 1 129 ? -5.271  -18.67  33.589  1 14.837 ? 121  ARG A CA  1 
ATOM   773  C  C   . ARG A 1 129 ? -4.246  -18.093 32.603  1 12.065 ? 121  ARG A C   1 
ATOM   774  O  O   . ARG A 1 129 ? -4.568  -17.876 31.42   1 13.166 ? 121  ARG A O   1 
ATOM   775  C  CB  . ARG A 1 129 ? -5.774  -17.683 34.634  1 12.493 ? 121  ARG A CB  1 
ATOM   776  C  CG  . ARG A 1 129 ? -5.863  -16.268 34.089  1 14.4   ? 121  ARG A CG  1 
ATOM   777  C  CD  . ARG A 1 129 ? -6.76   -15.504 35.032  1 13.536 ? 121  ARG A CD  1 
ATOM   778  N  NE  . ARG A 1 129 ? -7.07   -14.121 34.685  1 11.359 ? 121  ARG A NE  1 
ATOM   779  C  CZ  . ARG A 1 129 ? -7.883  -13.326 35.363  1 11.142 ? 121  ARG A CZ  1 
ATOM   780  N  NH1 . ARG A 1 129 ? -8.389  -13.736 36.5    1 11.144 ? 121  ARG A NH1 1 
ATOM   781  N  NH2 . ARG A 1 129 ? -7.995  -12.053 35.024  1 11.184 ? 121  ARG A NH2 1 
ATOM   782  N  N   . PHE A 1 130 ? -2.996  -17.924 33.081  1 13.994 ? 122  PHE A N   1 
ATOM   783  C  CA  . PHE A 1 130 ? -1.899  -17.427 32.274  1 13.909 ? 122  PHE A CA  1 
ATOM   784  C  C   . PHE A 1 130 ? -1.698  -18.317 31.078  1 13.317 ? 122  PHE A C   1 
ATOM   785  O  O   . PHE A 1 130 ? -1.488  -17.764 29.97   1 12.703 ? 122  PHE A O   1 
ATOM   786  C  CB  . PHE A 1 130 ? -0.611  -17.264 33.077  1 14.166 ? 122  PHE A CB  1 
ATOM   787  C  CG  . PHE A 1 130 ? 0.637   -16.931 32.269  1 14.265 ? 122  PHE A CG  1 
ATOM   788  C  CD1 . PHE A 1 130 ? 0.992   -15.601 31.994  1 13.65  ? 122  PHE A CD1 1 
ATOM   789  C  CD2 . PHE A 1 130 ? 1.484   -17.962 31.844  1 12.025 ? 122  PHE A CD2 1 
ATOM   790  C  CE1 . PHE A 1 130 ? 2.198   -15.298 31.309  1 14.09  ? 122  PHE A CE1 1 
ATOM   791  C  CE2 . PHE A 1 130 ? 2.688   -17.665 31.203  1 15.197 ? 122  PHE A CE2 1 
ATOM   792  C  CZ  . PHE A 1 130 ? 3.044   -16.33  30.937  1 14.96  ? 122  PHE A CZ  1 
ATOM   793  N  N   . LYS A 1 131 ? -1.689  -19.666 31.351  1 12.977 ? 123  LYS A N   1 
ATOM   794  C  CA  . LYS A 1 131 ? -1.406  -20.573 30.282  1 12.537 ? 123  LYS A CA  1 
ATOM   795  C  C   . LYS A 1 131 ? -2.442  -20.507 29.183  1 15.928 ? 123  LYS A C   1 
ATOM   796  O  O   . LYS A 1 131 ? -2.057  -20.533 27.99   1 15.12  ? 123  LYS A O   1 
ATOM   797  C  CB  . LYS A 1 131 ? -1.195  -21.967 30.858  1 16.971 ? 123  LYS A CB  1 
ATOM   798  C  CG  . LYS A 1 131 ? 0.009   -22.128 31.844  1 16.412 ? 123  LYS A CG  1 
ATOM   799  C  CD  . LYS A 1 131 ? 0.413   -23.575 32.075  1 13.87  ? 123  LYS A CD  1 
ATOM   800  C  CE  . LYS A 1 131 ? -0.581  -24.512 32.701  1 17.565 ? 123  LYS A CE  1 
ATOM   801  N  NZ  . LYS A 1 131 ? -1.455  -24.976 31.597  1 14.423 ? 123  LYS A NZ  1 
ATOM   802  N  N   . VAL A 1 132 ? -3.733  -20.498 29.588  1 15.643 ? 124  VAL A N   1 
ATOM   803  C  CA  . VAL A 1 132 ? -4.857  -20.37  28.669  1 15.108 ? 124  VAL A CA  1 
ATOM   804  C  C   . VAL A 1 132 ? -4.656  -19.154 27.776  1 13.379 ? 124  VAL A C   1 
ATOM   805  O  O   . VAL A 1 132 ? -4.686  -19.249 26.538  1 13.222 ? 124  VAL A O   1 
ATOM   806  C  CB  . VAL A 1 132 ? -6.197  -20.3   29.444  1 15.126 ? 124  VAL A CB  1 
ATOM   807  C  CG1 . VAL A 1 132 ? -7.376  -19.709 28.612  1 15.658 ? 124  VAL A CG1 1 
ATOM   808  C  CG2 . VAL A 1 132 ? -6.625  -21.703 29.937  1 18.417 ? 124  VAL A CG2 1 
ATOM   809  N  N   . GLU A 1 133 ? -4.49   -17.993 28.412  1 11.935 ? 125  GLU A N   1 
ATOM   810  C  CA  . GLU A 1 133 ? -4.352  -16.711 27.692  1 12.625 ? 125  GLU A CA  1 
ATOM   811  C  C   . GLU A 1 133 ? -3.102  -16.632 26.8    1 14.762 ? 125  GLU A C   1 
ATOM   812  O  O   . GLU A 1 133 ? -3.188  -16.097 25.677  1 17.269 ? 125  GLU A O   1 
ATOM   813  C  CB  . GLU A 1 133 ? -4.454  -15.49  28.633  1 12.361 ? 125  GLU A CB  1 
ATOM   814  C  CG  . GLU A 1 133 ? -5.866  -15.358 29.196  1 13.285 ? 125  GLU A CG  1 
ATOM   815  C  CD  . GLU A 1 133 ? -6.121  -14.121 30.027  1 13.018 ? 125  GLU A CD  1 
ATOM   816  O  OE1 . GLU A 1 133 ? -5.173  -13.364 30.44   1 14.214 ? 125  GLU A OE1 1 
ATOM   817  O  OE2 . GLU A 1 133 ? -7.328  -13.881 30.185  1 13.017 ? 125  GLU A OE2 1 
ATOM   818  N  N   . ARG A 1 134 ? -1.976  -17.23  27.251  1 14.22  ? 126  ARG A N   1 
ATOM   819  C  CA  . ARG A 1 134 ? -0.763  -17.133 26.447  1 14.997 ? 126  ARG A CA  1 
ATOM   820  C  C   . ARG A 1 134 ? -0.937  -18.047 25.234  1 14.769 ? 126  ARG A C   1 
ATOM   821  O  O   . ARG A 1 134 ? -0.624  -17.636 24.085  1 17.713 ? 126  ARG A O   1 
ATOM   822  C  CB  . ARG A 1 134 ? 0.505   -17.414 27.271  1 14.208 ? 126  ARG A CB  1 
ATOM   823  C  CG  . ARG A 1 134 ? 1.734   -17.586 26.357  1 14.94  ? 126  ARG A CG  1 
ATOM   824  C  CD  . ARG A 1 134 ? 3.047   -17.35  27.171  1 11.296 ? 126  ARG A CD  1 
ATOM   825  N  NE  . ARG A 1 134 ? 3.157   -15.923 27.489  1 12.189 ? 126  ARG A NE  1 
ATOM   826  C  CZ  . ARG A 1 134 ? 4.267   -15.344 27.947  1 15.806 ? 126  ARG A CZ  1 
ATOM   827  N  NH1 . ARG A 1 134 ? 5.31    -16.133 28.091  1 12.889 ? 126  ARG A NH1 1 
ATOM   828  N  NH2 . ARG A 1 134 ? 4.307   -14.084 28.391  1 14.353 ? 126  ARG A NH2 1 
ATOM   829  N  N   . ARG A 1 135 ? -1.521  -19.248 25.466  1 16.598 ? 127  ARG A N   1 
ATOM   830  C  CA  . ARG A 1 135 ? -1.615  -20.208 24.367  1 16.448 ? 127  ARG A CA  1 
ATOM   831  C  C   . ARG A 1 135 ? -2.591  -19.708 23.307  1 20.104 ? 127  ARG A C   1 
ATOM   832  O  O   . ARG A 1 135 ? -2.351  -19.91  22.081  1 17.819 ? 127  ARG A O   1 
ATOM   833  C  CB  . ARG A 1 135 ? -1.956  -21.605 24.891  1 19.159 ? 127  ARG A CB  1 
ATOM   834  C  CG  . ARG A 1 135 ? -0.833  -22.283 25.682  1 19.003 ? 127  ARG A CG  1 
ATOM   835  C  CD  . ARG A 1 135 ? -1.315  -23.544 26.384  1 20.168 ? 127  ARG A CD  1 
ATOM   836  N  NE  . ARG A 1 135 ? -1.732  -24.529 25.369  1 22.287 ? 127  ARG A NE  1 
ATOM   837  C  CZ  . ARG A 1 135 ? -0.977  -25.202 24.515  1 23.413 ? 127  ARG A CZ  1 
ATOM   838  N  NH1 . ARG A 1 135 ? 0.331   -25.268 24.651  1 23.002 ? 127  ARG A NH1 1 
ATOM   839  N  NH2 . ARG A 1 135 ? -1.55   -25.876 23.539  1 26.598 ? 127  ARG A NH2 1 
ATOM   840  N  N   . ALA A 1 136 ? -3.687  -19.084 23.804  1 20.049 ? 128  ALA A N   1 
ATOM   841  C  CA  . ALA A 1 136 ? -4.753  -18.485 23.011  1 19.614 ? 128  ALA A CA  1 
ATOM   842  C  C   . ALA A 1 136 ? -4.342  -17.155 22.371  1 17.218 ? 128  ALA A C   1 
ATOM   843  O  O   . ALA A 1 136 ? -5.016  -16.753 21.426  1 21.993 ? 128  ALA A O   1 
ATOM   844  C  CB  . ALA A 1 136 ? -6.052  -18.371 23.757  1 21.079 ? 128  ALA A CB  1 
ATOM   845  N  N   . ARG A 1 137 ? -3.264  -16.514 22.867  1 16.055 ? 129  ARG A N   1 
ATOM   846  C  CA  . ARG A 1 137 ? -2.858  -15.149 22.533  1 17.72  ? 129  ARG A CA  1 
ATOM   847  C  C   . ARG A 1 137 ? -4.109  -14.27  22.697  1 18.951 ? 129  ARG A C   1 
ATOM   848  O  O   . ARG A 1 137 ? -4.376  -13.392 21.863  1 16.366 ? 129  ARG A O   1 
ATOM   849  C  CB  . ARG A 1 137 ? -2.27   -15.098 21.094  1 15.967 ? 129  ARG A CB  1 
ATOM   850  C  CG  . ARG A 1 137 ? -1.653  -13.71  20.889  1 15.994 ? 129  ARG A CG  1 
ATOM   851  C  CD  . ARG A 1 137 ? -1.766  -13.169 19.459  1 18.302 ? 129  ARG A CD  1 
ATOM   852  N  NE  . ARG A 1 137 ? -1.299  -11.776 19.393  1 19.318 ? 129  ARG A NE  1 
ATOM   853  C  CZ  . ARG A 1 137 ? -1.21   -11.005 18.303  1 26.204 ? 129  ARG A CZ  1 
ATOM   854  N  NH1 . ARG A 1 137 ? -1.824  -11.307 17.196  1 19.948 ? 129  ARG A NH1 1 
ATOM   855  N  NH2 . ARG A 1 137 ? -0.502  -9.902  18.304  1 25.191 ? 129  ARG A NH2 1 
ATOM   856  N  N   . LYS A 1 138 ? -4.804  -14.415 23.846  1 12.471 ? 130  LYS A N   1 
ATOM   857  C  CA  . LYS A 1 138 ? -6.142  -13.811 23.939  1 16.799 ? 130  LYS A CA  1 
ATOM   858  C  C   . LYS A 1 138 ? -6.616  -13.746 25.385  1 16.605 ? 130  LYS A C   1 
ATOM   859  O  O   . LYS A 1 138 ? -6.495  -14.727 26.084  1 16.554 ? 130  LYS A O   1 
ATOM   860  C  CB  . LYS A 1 138 ? -7.202  -14.55  23.107  1 20.741 ? 130  LYS A CB  1 
ATOM   861  C  CG  . LYS A 1 138 ? -8.633  -13.946 22.962  1 23.033 ? 130  LYS A CG  1 
ATOM   862  C  CD  . LYS A 1 138 ? -9.574  -14.699 22.041  1 25.321 ? 130  LYS A CD  1 
ATOM   863  C  CE  . LYS A 1 138 ? -10.896 -13.968 22.1    1 25.308 ? 130  LYS A CE  1 
ATOM   864  N  NZ  . LYS A 1 138 ? -11.864 -14.35  21.067  1 25.569 ? 130  LYS A NZ  1 
ATOM   865  N  N   . SER A 1 139 ? -7.22   -12.609 25.77   1 13.927 ? 131  SER A N   1 
ATOM   866  C  CA  . SER A 1 139 ? -7.843  -12.532 27.09   1 16.57  ? 131  SER A CA  1 
ATOM   867  C  C   . SER A 1 139 ? -9.099  -13.41  27.057  1 14.304 ? 131  SER A C   1 
ATOM   868  O  O   . SER A 1 139 ? -9.891  -13.386 26.097  1 14.29  ? 131  SER A O   1 
ATOM   869  C  CB  . SER A 1 139 ? -8.175  -11.085 27.419  1 16.694 ? 131  SER A CB  1 
ATOM   870  O  OG  . SER A 1 139 ? -9.099  -10.972 28.497  1 12.454 ? 131  SER A OG  1 
ATOM   871  N  N   . MET A 1 140 ? -9.297  -14.189 28.133  1 12.675 ? 132  MET A N   1 
ATOM   872  C  CA  . MET A 1 140 ? -10.393 -15.137 28.262  1 14.186 ? 132  MET A CA  1 
ATOM   873  C  C   . MET A 1 140 ? -11.048 -15.014 29.634  1 12.792 ? 132  MET A C   1 
ATOM   874  O  O   . MET A 1 140 ? -11.98  -15.797 29.868  1 12.682 ? 132  MET A O   1 
ATOM   875  C  CB  . MET A 1 140 ? -9.936  -16.599 28.096  1 13.73  ? 132  MET A CB  1 
ATOM   876  C  CG  . MET A 1 140 ? -9.297  -16.852 26.7    1 18.213 ? 132  MET A CG  1 
ATOM   877  S  SD  . MET A 1 140 ? -10.479 -17.064 25.349  1 24.772 ? 132  MET A SD  1 
ATOM   878  C  CE  . MET A 1 140 ? -11.013 -18.781 25.419  1 20.112 ? 132  MET A CE  1 
ATOM   879  N  N   . TYR A 1 141 ? -10.585 -14.02  30.423  1 11.814 ? 133  TYR A N   1 
ATOM   880  C  CA  . TYR A 1 141 ? -11.087 -13.832 31.783  1 12.536 ? 133  TYR A CA  1 
ATOM   881  C  C   . TYR A 1 141 ? -11.691 -12.444 31.926  1 13.514 ? 133  TYR A C   1 
ATOM   882  O  O   . TYR A 1 141 ? -11.168 -11.52  31.323  1 15.92  ? 133  TYR A O   1 
ATOM   883  C  CB  . TYR A 1 141 ? -10.014 -14.15  32.815  1 10.719 ? 133  TYR A CB  1 
ATOM   884  C  CG  . TYR A 1 141 ? -9.673  -15.64  32.859  1 11.058 ? 133  TYR A CG  1 
ATOM   885  C  CD1 . TYR A 1 141 ? -8.77   -16.203 31.971  1 12.467 ? 133  TYR A CD1 1 
ATOM   886  C  CD2 . TYR A 1 141 ? -10.233 -16.452 33.868  1 12.227 ? 133  TYR A CD2 1 
ATOM   887  C  CE1 . TYR A 1 141 ? -8.471  -17.558 32.014  1 13.783 ? 133  TYR A CE1 1 
ATOM   888  C  CE2 . TYR A 1 141 ? -9.896  -17.8   33.957  1 15.215 ? 133  TYR A CE2 1 
ATOM   889  C  CZ  . TYR A 1 141 ? -9.039  -18.354 33.009  1 14.085 ? 133  TYR A CZ  1 
ATOM   890  O  OH  . TYR A 1 141 ? -8.673  -19.683 33.052  1 13.797 ? 133  TYR A OH  1 
ATOM   891  N  N   . GLY A 1 142 ? -12.775 -12.328 32.7    1 16.048 ? 134  GLY A N   1 
ATOM   892  C  CA  . GLY A 1 142 ? -13.426 -11.033 32.924  1 11.988 ? 134  GLY A CA  1 
ATOM   893  C  C   . GLY A 1 142 ? -13.013 -10.381 34.244  1 11.963 ? 134  GLY A C   1 
ATOM   894  O  O   . GLY A 1 142 ? -11.868 -10.041 34.435  1 14.33  ? 134  GLY A O   1 
ATOM   895  N  N   . LEU A 1 143 ? -14.012 -9.991  35.035  1 13.172 ? 135  LEU A N   1 
ATOM   896  C  CA  . LEU A 1 143 ? -13.844 -9.228  36.258  1 12.548 ? 135  LEU A CA  1 
ATOM   897  C  C   . LEU A 1 143 ? -13.119 -10.053 37.333  1 14.707 ? 135  LEU A C   1 
ATOM   898  O  O   . LEU A 1 143 ? -13.191 -11.28  37.395  1 14.133 ? 135  LEU A O   1 
ATOM   899  C  CB  . LEU A 1 143 ? -15.194 -8.698  36.779  1 13.254 ? 135  LEU A CB  1 
ATOM   900  C  CG  . LEU A 1 143 ? -16.086 -7.864  35.839  1 13.819 ? 135  LEU A CG  1 
ATOM   901  C  CD1 . LEU A 1 143 ? -17.372 -7.458  36.621  1 18.147 ? 135  LEU A CD1 1 
ATOM   902  C  CD2 . LEU A 1 143 ? -15.336 -6.55   35.422  1 13.334 ? 135  LEU A CD2 1 
ATOM   903  N  N   . TYR A 1 144 ? -12.46  -9.335  38.235  1 13.617 ? 136  TYR A N   1 
ATOM   904  C  CA  . TYR A 1 144 ? -11.815 -9.923  39.394  1 14.284 ? 136  TYR A CA  1 
ATOM   905  C  C   . TYR A 1 144 ? -12.824 -10.799 40.124  1 12.927 ? 136  TYR A C   1 
ATOM   906  O  O   . TYR A 1 144 ? -13.846 -10.306 40.567  1 13.872 ? 136  TYR A O   1 
ATOM   907  C  CB  . TYR A 1 144 ? -11.576 -8.761  40.353  1 11.606 ? 136  TYR A CB  1 
ATOM   908  C  CG  . TYR A 1 144 ? -10.952 -9.125  41.672  1 12.903 ? 136  TYR A CG  1 
ATOM   909  C  CD1 . TYR A 1 144 ? -9.599  -9.528  41.67   1 12.797 ? 136  TYR A CD1 1 
ATOM   910  C  CD2 . TYR A 1 144 ? -11.682 -9.023  42.862  1 12.408 ? 136  TYR A CD2 1 
ATOM   911  C  CE1 . TYR A 1 144 ? -9.013  -9.835  42.864  1 12.56  ? 136  TYR A CE1 1 
ATOM   912  C  CE2 . TYR A 1 144 ? -11.081 -9.33   44.063  1 11.372 ? 136  TYR A CE2 1 
ATOM   913  C  CZ  . TYR A 1 144 ? -9.746  -9.728  44.021  1 11.928 ? 136  TYR A CZ  1 
ATOM   914  O  OH  . TYR A 1 144 ? -9.006  -10.038 45.079  1 12.578 ? 136  TYR A OH  1 
ATOM   915  N  N   . ARG A 1 145 ? -12.482 -12.073 40.368  1 11.421 ? 137  ARG A N   1 
ATOM   916  C  CA  . ARG A 1 145 ? -13.346 -12.99  41.114  1 10.94  ? 137  ARG A CA  1 
ATOM   917  C  C   . ARG A 1 145 ? -14.756 -13.102 40.563  1 11.683 ? 137  ARG A C   1 
ATOM   918  O  O   . ARG A 1 145 ? -15.726 -13.411 41.289  1 13.426 ? 137  ARG A O   1 
ATOM   919  C  CB  . ARG A 1 145 ? -13.209 -12.769 42.646  1 9.959  ? 137  ARG A CB  1 
ATOM   920  C  CG  . ARG A 1 145 ? -11.753 -12.687 43.037  1 9.439  ? 137  ARG A CG  1 
ATOM   921  C  CD  . ARG A 1 145 ? -11.763 -12.696 44.635  1 11.958 ? 137  ARG A CD  1 
ATOM   922  N  NE  . ARG A 1 145 ? -12.285 -13.961 45.145  1 9.974  ? 137  ARG A NE  1 
ATOM   923  C  CZ  . ARG A 1 145 ? -12.141 -14.421 46.405  1 13.463 ? 137  ARG A CZ  1 
ATOM   924  N  NH1 . ARG A 1 145 ? -11.606 -13.629 47.354  1 12.616 ? 137  ARG A NH1 1 
ATOM   925  N  NH2 . ARG A 1 145 ? -12.507 -15.69  46.642  1 10.244 ? 137  ARG A NH2 1 
ATOM   926  N  N   . ASN A 1 146 ? -14.911 -12.93  39.21   1 11.024 ? 138  ASN A N   1 
ATOM   927  C  CA  . ASN A 1 146 ? -16.24  -13.256 38.716  1 10.79  ? 138  ASN A CA  1 
ATOM   928  C  C   . ASN A 1 146 ? -16.171 -14.226 37.545  1 9.903  ? 138  ASN A C   1 
ATOM   929  O  O   . ASN A 1 146 ? -16.179 -13.768 36.403  1 10.104 ? 138  ASN A O   1 
ATOM   930  C  CB  . ASN A 1 146 ? -16.994 -11.971 38.342  1 10.735 ? 138  ASN A CB  1 
ATOM   931  C  CG  . ASN A 1 146 ? -18.46  -12.302 38.188  1 10.003 ? 138  ASN A CG  1 
ATOM   932  O  OD1 . ASN A 1 146 ? -18.845 -13.47  38.085  1 11.024 ? 138  ASN A OD1 1 
ATOM   933  N  ND2 . ASN A 1 146 ? -19.291 -11.276 38.148  1 11.406 ? 138  ASN A ND2 1 
ATOM   934  N  N   . PRO A 1 147 ? -16.208 -15.555 37.795  1 11.668 ? 139  PRO A N   1 
ATOM   935  C  CA  . PRO A 1 147 ? -16.279 -16.553 36.729  1 11.129 ? 139  PRO A CA  1 
ATOM   936  C  C   . PRO A 1 147 ? -17.467 -16.399 35.762  1 13.292 ? 139  PRO A C   1 
ATOM   937  O  O   . PRO A 1 147 ? -17.37  -16.842 34.626  1 15.308 ? 139  PRO A O   1 
ATOM   938  C  CB  . PRO A 1 147 ? -16.41  -17.846 37.54   1 11.207 ? 139  PRO A CB  1 
ATOM   939  C  CG  . PRO A 1 147 ? -15.529 -17.497 38.795  1 11.949 ? 139  PRO A CG  1 
ATOM   940  C  CD  . PRO A 1 147 ? -15.987 -16.153 39.13   1 10.14  ? 139  PRO A CD  1 
ATOM   941  N  N   . TYR A 1 148 ? -18.563 -15.727 36.17   1 13.003 ? 140  TYR A N   1 
ATOM   942  C  CA  . TYR A 1 148 ? -19.723 -15.556 35.297  1 17.142 ? 140  TYR A CA  1 
ATOM   943  C  C   . TYR A 1 148 ? -19.407 -14.618 34.111  1 14.657 ? 140  TYR A C   1 
ATOM   944  O  O   . TYR A 1 148 ? -20.216 -14.479 33.175  1 13.209 ? 140  TYR A O   1 
ATOM   945  C  CB  . TYR A 1 148 ? -20.963 -15.163 36.101  1 15.483 ? 140  TYR A CB  1 
ATOM   946  C  CG  . TYR A 1 148 ? -21.408 -16.257 37.074  1 13.781 ? 140  TYR A CG  1 
ATOM   947  C  CD1 . TYR A 1 148 ? -22.081 -17.422 36.633  1 15.994 ? 140  TYR A CD1 1 
ATOM   948  C  CD2 . TYR A 1 148 ? -21.121 -16.126 38.432  1 14.856 ? 140  TYR A CD2 1 
ATOM   949  C  CE1 . TYR A 1 148 ? -22.416 -18.437 37.54   1 13.59  ? 140  TYR A CE1 1 
ATOM   950  C  CE2 . TYR A 1 148 ? -21.51  -17.1   39.335  1 12.3   ? 140  TYR A CE2 1 
ATOM   951  C  CZ  . TYR A 1 148 ? -22.143 -18.249 38.879  1 11.794 ? 140  TYR A CZ  1 
ATOM   952  O  OH  . TYR A 1 148 ? -22.436 -19.118 39.892  1 14.508 ? 140  TYR A OH  1 
ATOM   953  N  N   . THR A 1 149 ? -18.294 -13.886 34.23   1 10.934 ? 141  THR A N   1 
ATOM   954  C  CA  . THR A 1 149 ? -17.791 -12.973 33.197  1 15.33  ? 141  THR A CA  1 
ATOM   955  C  C   . THR A 1 149 ? -16.554 -13.533 32.483  1 14.654 ? 141  THR A C   1 
ATOM   956  O  O   . THR A 1 149 ? -15.98  -12.836 31.653  1 16.124 ? 141  THR A O   1 
ATOM   957  C  CB  . THR A 1 149 ? -17.452 -11.609 33.807  1 16.339 ? 141  THR A CB  1 
ATOM   958  O  OG1 . THR A 1 149 ? -16.349 -11.631 34.72   1 16.359 ? 141  THR A OG1 1 
ATOM   959  C  CG2 . THR A 1 149 ? -18.651 -10.962 34.481  1 17.154 ? 141  THR A CG2 1 
ATOM   960  N  N   . HIS A 1 150 ? -16.172 -14.785 32.768  1 11.759 ? 142  HIS A N   1 
ATOM   961  C  CA  . HIS A 1 150 ? -15.068 -15.399 32.058  1 14.359 ? 142  HIS A CA  1 
ATOM   962  C  C   . HIS A 1 150 ? -15.65  -16.045 30.821  1 14.416 ? 142  HIS A C   1 
ATOM   963  O  O   . HIS A 1 150 ? -16.885 -16.153 30.734  1 15.558 ? 142  HIS A O   1 
ATOM   964  C  CB  . HIS A 1 150 ? -14.27  -16.352 32.943  1 13.404 ? 142  HIS A CB  1 
ATOM   965  C  CG  . HIS A 1 150 ? -13.687 -15.756 34.196  1 15.376 ? 142  HIS A CG  1 
ATOM   966  N  ND1 . HIS A 1 150 ? -13.399 -14.438 34.42   1 14.152 ? 142  HIS A ND1 1 
ATOM   967  C  CD2 . HIS A 1 150 ? -13.277 -16.426 35.306  1 12.932 ? 142  HIS A CD2 1 
ATOM   968  C  CE1 . HIS A 1 150 ? -12.988 -14.299 35.668  1 13.657 ? 142  HIS A CE1 1 
ATOM   969  N  NE2 . HIS A 1 150 ? -12.853 -15.513 36.237  1 13.673 ? 142  HIS A NE2 1 
ATOM   970  N  N   . HIS A 1 151 ? -14.78  -16.405 29.866  1 13.558 ? 143  HIS A N   1 
ATOM   971  C  CA  . HIS A 1 151 ? -15.206 -17.127 28.671  1 15.87  ? 143  HIS A CA  1 
ATOM   972  C  C   . HIS A 1 151 ? -15.761 -18.488 29.134  1 17.686 ? 143  HIS A C   1 
ATOM   973  O  O   . HIS A 1 151 ? -15.191 -19.099 30.053  1 16.109 ? 143  HIS A O   1 
ATOM   974  C  CB  . HIS A 1 151 ? -14.046 -17.433 27.728  1 14.509 ? 143  HIS A CB  1 
ATOM   975  C  CG  . HIS A 1 151 ? -14.413 -18.064 26.414  1 17.618 ? 143  HIS A CG  1 
ATOM   976  N  ND1 . HIS A 1 151 ? -14.698 -19.41  26.318  1 17.935 ? 143  HIS A ND1 1 
ATOM   977  C  CD2 . HIS A 1 151 ? -14.462 -17.583 25.166  1 16.621 ? 143  HIS A CD2 1 
ATOM   978  C  CE1 . HIS A 1 151 ? -14.926 -19.714 25.029  1 16.148 ? 143  HIS A CE1 1 
ATOM   979  N  NE2 . HIS A 1 151 ? -14.715 -18.645 24.332  1 15.737 ? 143  HIS A NE2 1 
ATOM   980  N  N   . PRO A 1 152 ? -16.951 -18.928 28.602  1 19.449 ? 144  PRO A N   1 
ATOM   981  C  CA  . PRO A 1 152 ? -17.594 -20.187 28.991  1 20.222 ? 144  PRO A CA  1 
ATOM   982  C  C   . PRO A 1 152 ? -16.648 -21.372 29.153  1 17.881 ? 144  PRO A C   1 
ATOM   983  O  O   . PRO A 1 152 ? -16.79  -22.126 30.132  1 17.13  ? 144  PRO A O   1 
ATOM   984  C  CB  . PRO A 1 152 ? -18.824 -20.316 28.054  1 20.752 ? 144  PRO A CB  1 
ATOM   985  C  CG  . PRO A 1 152 ? -18.669 -19.21  27.073  1 22.907 ? 144  PRO A CG  1 
ATOM   986  C  CD  . PRO A 1 152 ? -17.745 -18.194 27.609  1 18.592 ? 144  PRO A CD  1 
ATOM   987  N  N   . CYS A 1 153 ? -15.607 -21.437 28.315  1 17.046 ? 145  CYS A N   1 
ATOM   988  C  CA  . CYS A 1 153 ? -14.689 -22.586 28.325  1 19.753 ? 145  CYS A CA  1 
ATOM   989  C  C   . CYS A 1 153 ? -13.768 -22.571 29.547  1 18.848 ? 145  CYS A C   1 
ATOM   990  O  O   . CYS A 1 153 ? -13.274 -23.642 29.9    1 21.832 ? 145  CYS A O   1 
ATOM   991  C  CB  . CYS A 1 153 ? -13.865 -22.692 27.055  1 24.582 ? 145  CYS A CB  1 
ATOM   992  S  SG  . CYS A 1 153 ? -14.893 -23.279 25.688  1 31.205 ? 145  CYS A SG  1 
ATOM   993  N  N   . VAL A 1 154 ? -13.588 -21.408 30.201  1 16.651 ? 146  VAL A N   1 
ATOM   994  C  CA  . VAL A 1 154 ? -12.684 -21.287 31.351  1 14.744 ? 146  VAL A CA  1 
ATOM   995  C  C   . VAL A 1 154 ? -13.388 -21.07  32.701  1 18.06  ? 146  VAL A C   1 
ATOM   996  O  O   . VAL A 1 154 ? -12.699 -20.884 33.721  1 14.006 ? 146  VAL A O   1 
ATOM   997  C  CB  . VAL A 1 154 ? -11.53  -20.278 31.078  1 17.208 ? 146  VAL A CB  1 
ATOM   998  C  CG1 . VAL A 1 154 ? -10.878 -20.517 29.714  1 18.749 ? 146  VAL A CG1 1 
ATOM   999  C  CG2 . VAL A 1 154 ? -11.993 -18.841 31.063  1 16.381 ? 146  VAL A CG2 1 
ATOM   1000 N  N   . ARG A 1 155 ? -14.734 -21.133 32.753  1 15.898 ? 147  ARG A N   1 
ATOM   1001 C  CA  . ARG A 1 155 ? -15.42  -20.694 33.967  1 16.812 ? 147  ARG A CA  1 
ATOM   1002 C  C   . ARG A 1 155 ? -15.087 -21.608 35.141  1 15.842 ? 147  ARG A C   1 
ATOM   1003 O  O   . ARG A 1 155 ? -15.052 -21.148 36.291  1 13.042 ? 147  ARG A O   1 
ATOM   1004 C  CB  . ARG A 1 155 ? -16.956 -20.802 33.844  1 17.617 ? 147  ARG A CB  1 
ATOM   1005 C  CG  . ARG A 1 155 ? -17.528 -19.598 33.121  1 24.525 ? 147  ARG A CG  1 
ATOM   1006 C  CD  . ARG A 1 155 ? -19.019 -19.425 33.234  1 23.747 ? 147  ARG A CD  1 
ATOM   1007 N  NE  . ARG A 1 155 ? -19.092 -18.263 32.333  1 28.144 ? 147  ARG A NE  1 
ATOM   1008 C  CZ  . ARG A 1 155 ? -20.028 -17.924 31.455  1 30.69  ? 147  ARG A CZ  1 
ATOM   1009 N  NH1 . ARG A 1 155 ? -21.179 -18.614 31.471  1 33.455 ? 147  ARG A NH1 1 
ATOM   1010 N  NH2 . ARG A 1 155 ? -19.804 -16.888 30.616  1 22.116 ? 147  ARG A NH2 1 
ATOM   1011 N  N   . GLN A 1 156 ? -14.821 -22.891 34.84   1 18.06  ? 148  GLN A N   1 
ATOM   1012 C  CA  . GLN A 1 156 ? -14.52  -23.872 35.866  1 19.149 ? 148  GLN A CA  1 
ATOM   1013 C  C   . GLN A 1 156 ? -13.026 -24.125 36.011  1 18.365 ? 148  GLN A C   1 
ATOM   1014 O  O   . GLN A 1 156 ? -12.598 -25.22  36.375  1 23.175 ? 148  GLN A O   1 
ATOM   1015 C  CB  . GLN A 1 156 ? -15.443 -25.068 35.584  1 21.017 ? 148  GLN A CB  1 
ATOM   1016 C  CG  . GLN A 1 156 ? -15.775 -25.786 36.891  1 27.514 ? 148  GLN A CG  1 
ATOM   1017 C  CD  . GLN A 1 156 ? -16.807 -26.896 36.755  1 27.566 ? 148  GLN A CD  1 
ATOM   1018 O  OE1 . GLN A 1 156 ? -17.388 -27.136 35.683  1 26.948 ? 148  GLN A OE1 1 
ATOM   1019 N  NE2 . GLN A 1 156 ? -17.052 -27.54  37.887  1 26.744 ? 148  GLN A NE2 1 
ATOM   1020 N  N   . THR A 1 157 ? -12.213 -23.101 35.722  1 15.155 ? 149  THR A N   1 
ATOM   1021 C  CA  . THR A 1 157 ? -10.778 -23.161 35.936  1 16.047 ? 149  THR A CA  1 
ATOM   1022 C  C   . THR A 1 157 ? -10.473 -22.511 37.283  1 15.508 ? 149  THR A C   1 
ATOM   1023 O  O   . THR A 1 157 ? -11.315 -21.79  37.829  1 13.419 ? 149  THR A O   1 
ATOM   1024 C  CB  . THR A 1 157 ? -9.962  -22.498 34.836  1 15.227 ? 149  THR A CB  1 
ATOM   1025 O  OG1 . THR A 1 157 ? -10.49  -21.169 34.766  1 17.167 ? 149  THR A OG1 1 
ATOM   1026 C  CG2 . THR A 1 157 ? -10.019 -23.232 33.515  1 15.311 ? 149  THR A CG2 1 
ATOM   1027 N  N   . VAL A 1 158 ? -9.243  -22.708 37.739  1 15.978 ? 150  VAL A N   1 
ATOM   1028 C  CA  . VAL A 1 158 ? -8.714  -21.876 38.828  1 15.167 ? 150  VAL A CA  1 
ATOM   1029 C  C   . VAL A 1 158 ? -8.428  -20.524 38.156  1 12.755 ? 150  VAL A C   1 
ATOM   1030 O  O   . VAL A 1 158 ? -7.7    -20.477 37.15   1 14.576 ? 150  VAL A O   1 
ATOM   1031 C  CB  . VAL A 1 158 ? -7.447  -22.528 39.455  1 17.652 ? 150  VAL A CB  1 
ATOM   1032 C  CG1 . VAL A 1 158 ? -6.61   -21.563 40.299  1 14.771 ? 150  VAL A CG1 1 
ATOM   1033 C  CG2 . VAL A 1 158 ? -7.815  -23.755 40.247  1 16.415 ? 150  VAL A CG2 1 
ATOM   1034 N  N   . GLU A 1 159 ? -9.076  -19.469 38.666  1 9.812  ? 151  GLU A N   1 
ATOM   1035 C  CA  . GLU A 1 159 ? -9.044  -18.141 38.045  1 10.14  ? 151  GLU A CA  1 
ATOM   1036 C  C   . GLU A 1 159 ? -7.926  -17.25  38.638  1 11.826 ? 151  GLU A C   1 
ATOM   1037 O  O   . GLU A 1 159 ? -7.708  -16.132 38.174  1 11.733 ? 151  GLU A O   1 
ATOM   1038 C  CB  . GLU A 1 159 ? -10.409 -17.44  38.133  1 9.471  ? 151  GLU A CB  1 
ATOM   1039 C  CG  . GLU A 1 159 ? -10.776 -17.175 39.608  1 12.182 ? 151  GLU A CG  1 
ATOM   1040 C  CD  . GLU A 1 159 ? -11.849 -16.102 39.761  1 12.351 ? 151  GLU A CD  1 
ATOM   1041 O  OE1 . GLU A 1 159 ? -12.373 -15.548 38.731  1 14.982 ? 151  GLU A OE1 1 
ATOM   1042 O  OE2 . GLU A 1 159 ? -12.122 -15.85  40.969  1 14.106 ? 151  GLU A OE2 1 
ATOM   1043 N  N   . SER A 1 160 ? -7.215  -17.748 39.654  1 11.459 ? 152  SER A N   1 
ATOM   1044 C  CA  . SER A 1 160 ? -6.158  -17.003 40.331  1 13.826 ? 152  SER A CA  1 
ATOM   1045 C  C   . SER A 1 160 ? -5.024  -16.538 39.401  1 12.232 ? 152  SER A C   1 
ATOM   1046 O  O   . SER A 1 160 ? -4.518  -17.289 38.56   1 13.92  ? 152  SER A O   1 
ATOM   1047 C  CB  . SER A 1 160 ? -5.626  -17.849 41.497  1 11.625 ? 152  SER A CB  1 
ATOM   1048 O  OG  . SER A 1 160 ? -4.46   -17.172 41.859  1 10.346 ? 152  SER A OG  1 
ATOM   1049 N  N   . THR A 1 161 ? -4.643  -15.25  39.509  1 12.115 ? 153  THR A N   1 
ATOM   1050 C  CA  . THR A 1 161 ? -3.472  -14.718 38.811  1 12.791 ? 153  THR A CA  1 
ATOM   1051 C  C   . THR A 1 161 ? -2.239  -14.814 39.722  1 12.24  ? 153  THR A C   1 
ATOM   1052 O  O   . THR A 1 161 ? -1.213  -14.295 39.333  1 13.76  ? 153  THR A O   1 
ATOM   1053 C  CB  . THR A 1 161 ? -3.733  -13.259 38.329  1 10.084 ? 153  THR A CB  1 
ATOM   1054 O  OG1 . THR A 1 161 ? -4.361  -12.615 39.425  1 11.767 ? 153  THR A OG1 1 
ATOM   1055 C  CG2 . THR A 1 161 ? -4.709  -13.159 37.155  1 9.61   ? 153  THR A CG2 1 
ATOM   1056 N  N   . ALA A 1 162 ? -2.394  -15.267 40.998  1 11.135 ? 154  ALA A N   1 
ATOM   1057 C  CA  . ALA A 1 162 ? -1.233  -15.504 41.865  1 10.388 ? 154  ALA A CA  1 
ATOM   1058 C  C   . ALA A 1 162 ? -0.283  -14.3   41.877  1 10.639 ? 154  ALA A C   1 
ATOM   1059 O  O   . ALA A 1 162 ? 0.909   -14.414 41.563  1 12.539 ? 154  ALA A O   1 
ATOM   1060 C  CB  . ALA A 1 162 ? -0.439  -16.754 41.424  1 10.817 ? 154  ALA A CB  1 
ATOM   1061 N  N   . ASN A 1 163 ? -0.794  -13.159 42.29   1 11.136 ? 155  ASN A N   1 
ATOM   1062 C  CA  . ASN A 1 163 ? -0.069  -11.9   42.048  1 10.036 ? 155  ASN A CA  1 
ATOM   1063 C  C   . ASN A 1 163 ? 0.029   -11.012 43.283  1 10.348 ? 155  ASN A C   1 
ATOM   1064 O  O   . ASN A 1 163 ? 0.421   -9.851  43.155  1 12.559 ? 155  ASN A O   1 
ATOM   1065 C  CB  . ASN A 1 163 ? -0.719  -11.103 40.932  1 11.934 ? 155  ASN A CB  1 
ATOM   1066 C  CG  . ASN A 1 163 ? -2.131  -10.628 41.309  1 10.8   ? 155  ASN A CG  1 
ATOM   1067 O  OD1 . ASN A 1 163 ? -2.656  -10.927 42.393  1 11.075 ? 155  ASN A OD1 1 
ATOM   1068 N  ND2 . ASN A 1 163 ? -2.68   -9.795  40.466  1 10.889 ? 155  ASN A ND2 1 
ATOM   1069 N  N   . THR A 1 164 ? -0.198  -11.556 44.488  1 12.288 ? 156  THR A N   1 
ATOM   1070 C  CA  . THR A 1 164 ? -0.279  -10.744 45.697  1 12.918 ? 156  THR A CA  1 
ATOM   1071 C  C   . THR A 1 164 ? 0.926   -10.868 46.613  1 13.178 ? 156  THR A C   1 
ATOM   1072 O  O   . THR A 1 164 ? 1.459   -9.851  47.001  1 11.243 ? 156  THR A O   1 
ATOM   1073 C  CB  . THR A 1 164 ? -1.59   -11.124 46.4    1 16.324 ? 156  THR A CB  1 
ATOM   1074 O  OG1 . THR A 1 164 ? -2.64   -10.905 45.464  1 19.481 ? 156  THR A OG1 1 
ATOM   1075 C  CG2 . THR A 1 164 ? -1.769  -10.551 47.784  1 15.516 ? 156  THR A CG2 1 
ATOM   1076 N  N   . ASN A 1 165 ? 1.436   -12.084 46.867  1 11.711 ? 157  ASN A N   1 
ATOM   1077 C  CA  . ASN A 1 165 ? 2.45    -12.238 47.911  1 10.627 ? 157  ASN A CA  1 
ATOM   1078 C  C   . ASN A 1 165 ? 3.199   -13.557 47.674  1 10.733 ? 157  ASN A C   1 
ATOM   1079 O  O   . ASN A 1 165 ? 2.744   -14.41  46.905  1 11.679 ? 157  ASN A O   1 
ATOM   1080 C  CB  . ASN A 1 165 ? 1.856   -12.127 49.314  1 8.974  ? 157  ASN A CB  1 
ATOM   1081 C  CG  . ASN A 1 165 ? 2.868   -12.015 50.437  1 11.284 ? 157  ASN A CG  1 
ATOM   1082 O  OD1 . ASN A 1 165 ? 4.064   -11.678 50.246  1 12.211 ? 157  ASN A OD1 1 
ATOM   1083 N  ND2 . ASN A 1 165 ? 2.412   -12.295 51.662  1 11.654 ? 157  ASN A ND2 1 
ATOM   1084 N  N   . VAL A 1 166 ? 4.361   -13.702 48.35   1 12.39  ? 158  VAL A N   1 
ATOM   1085 C  CA  . VAL A 1 166 ? 5.186   -14.885 48.2    1 11.772 ? 158  VAL A CA  1 
ATOM   1086 C  C   . VAL A 1 166 ? 5.607   -15.381 49.583  1 10.274 ? 158  VAL A C   1 
ATOM   1087 O  O   . VAL A 1 166 ? 5.519   -14.635 50.586  1 10.821 ? 158  VAL A O   1 
ATOM   1088 C  CB  . VAL A 1 166 ? 6.389   -14.74  47.27   1 12.346 ? 158  VAL A CB  1 
ATOM   1089 C  CG1 . VAL A 1 166 ? 5.898   -14.471 45.817  1 10.518 ? 158  VAL A CG1 1 
ATOM   1090 C  CG2 . VAL A 1 166 ? 7.356   -13.653 47.799  1 13.974 ? 158  VAL A CG2 1 
ATOM   1091 N  N   . VAL A 1 167 ? 5.939   -16.696 49.626  1 11.223 ? 159  VAL A N   1 
ATOM   1092 C  CA  . VAL A 1 167 ? 6.432   -17.277 50.89   1 11.527 ? 159  VAL A CA  1 
ATOM   1093 C  C   . VAL A 1 167 ? 7.342   -18.47  50.563  1 11.641 ? 159  VAL A C   1 
ATOM   1094 O  O   . VAL A 1 167 ? 7.138   -19.129 49.537  1 14.062 ? 159  VAL A O   1 
ATOM   1095 C  CB  . VAL A 1 167 ? 5.273   -17.653 51.831  1 11.353 ? 159  VAL A CB  1 
ATOM   1096 C  CG1 . VAL A 1 167 ? 4.383   -18.799 51.334  1 10.276 ? 159  VAL A CG1 1 
ATOM   1097 C  CG2 . VAL A 1 167 ? 5.754   -17.862 53.282  1 11.849 ? 159  VAL A CG2 1 
ATOM   1098 N  N   . MET A 1 168 ? 8.339   -18.74  51.423  1 14.065 ? 160  MET A N   1 
ATOM   1099 C  CA  . MET A 1 168 ? 9.179   -19.939 51.296  1 11.824 ? 160  MET A CA  1 
ATOM   1100 C  C   . MET A 1 168 ? 8.896   -20.736 52.564  1 15.072 ? 160  MET A C   1 
ATOM   1101 O  O   . MET A 1 168 ? 9.187   -20.225 53.678  1 13.018 ? 160  MET A O   1 
ATOM   1102 C  CB  . MET A 1 168 ? 10.673  -19.506 51.346  1 15.947 ? 160  MET A CB  1 
ATOM   1103 C  CG  . MET A 1 168 ? 11.64   -20.736 51.283  1 14.606 ? 160  MET A CG  1 
ATOM   1104 S  SD  . MET A 1 168 ? 11.539  -21.64  49.716  1 19.596 ? 160  MET A SD  1 
ATOM   1105 C  CE  . MET A 1 168 ? 12.613  -20.519 48.819  1 20.113 ? 160  MET A CE  1 
ATOM   1106 N  N   . HIS A 1 169 ? 8.243   -21.91  52.388  1 13.502 ? 161  HIS A N   1 
ATOM   1107 C  CA  . HIS A 1 169 ? 7.847   -22.711 53.545  1 16.635 ? 161  HIS A CA  1 
ATOM   1108 C  C   . HIS A 1 169 ? 8.144   -24.168 53.257  1 14.903 ? 161  HIS A C   1 
ATOM   1109 O  O   . HIS A 1 169 ? 7.805   -24.687 52.168  1 15.421 ? 161  HIS A O   1 
ATOM   1110 C  CB  . HIS A 1 169 ? 6.361   -22.54  53.894  1 14.738 ? 161  HIS A CB  1 
ATOM   1111 C  CG  . HIS A 1 169 ? 6.019   -23.255 55.182  1 13.398 ? 161  HIS A CG  1 
ATOM   1112 N  ND1 . HIS A 1 169 ? 6.463   -22.818 56.42   1 16.595 ? 161  HIS A ND1 1 
ATOM   1113 C  CD2 . HIS A 1 169 ? 5.456   -24.425 55.402  1 15.072 ? 161  HIS A CD2 1 
ATOM   1114 C  CE1 . HIS A 1 169 ? 6.072   -23.629 57.391  1 13.244 ? 161  HIS A CE1 1 
ATOM   1115 N  NE2 . HIS A 1 169 ? 5.493   -24.649 56.807  1 13.683 ? 161  HIS A NE2 1 
ATOM   1116 N  N   . ALA A 1 170 ? 8.806   -24.798 54.229  1 15.528 ? 162  ALA A N   1 
ATOM   1117 C  CA  . ALA A 1 170 ? 9.19    -26.218 54.136  1 16.65  ? 162  ALA A CA  1 
ATOM   1118 C  C   . ALA A 1 170 ? 9.878   -26.517 52.786  1 16.307 ? 162  ALA A C   1 
ATOM   1119 O  O   . ALA A 1 170 ? 9.649   -27.557 52.162  1 18.244 ? 162  ALA A O   1 
ATOM   1120 C  CB  . ALA A 1 170 ? 7.903   -27.038 54.312  1 17.097 ? 162  ALA A CB  1 
ATOM   1121 N  N   . GLY A 1 171 ? 10.811  -25.627 52.421  1 14.555 ? 163  GLY A N   1 
ATOM   1122 C  CA  . GLY A 1 171 ? 11.657  -25.724 51.242  1 14.352 ? 163  GLY A CA  1 
ATOM   1123 C  C   . GLY A 1 171 ? 10.91   -25.419 49.951  1 15.775 ? 163  GLY A C   1 
ATOM   1124 O  O   . GLY A 1 171 ? 11.514  -25.61  48.876  1 14.215 ? 163  GLY A O   1 
ATOM   1125 N  N   . ARG A 1 172 ? 9.647   -24.948 50.063  1 16.046 ? 164  ARG A N   1 
ATOM   1126 C  CA  . ARG A 1 172 ? 8.79    -24.703 48.887  1 15.42  ? 164  ARG A CA  1 
ATOM   1127 C  C   . ARG A 1 172 ? 8.457   -23.22  48.744  1 16.266 ? 164  ARG A C   1 
ATOM   1128 O  O   . ARG A 1 172 ? 8.071   -22.55  49.713  1 15.673 ? 164  ARG A O   1 
ATOM   1129 C  CB  . ARG A 1 172 ? 7.434   -25.373 49.09   1 15.684 ? 164  ARG A CB  1 
ATOM   1130 C  CG  . ARG A 1 172 ? 7.589   -26.884 49.226  1 19.2   ? 164  ARG A CG  1 
ATOM   1131 C  CD  . ARG A 1 172 ? 6.301   -27.418 48.834  1 22.892 ? 164  ARG A CD  1 
ATOM   1132 N  NE  . ARG A 1 172 ? 6.388   -28.869 48.802  1 29.848 ? 164  ARG A NE  1 
ATOM   1133 C  CZ  . ARG A 1 172 ? 6.181   -29.717 47.822  1 29.778 ? 164  ARG A CZ  1 
ATOM   1134 N  NH1 . ARG A 1 172 ? 5.885   -29.414 46.576  1 23.329 ? 164  ARG A NH1 1 
ATOM   1135 N  NH2 . ARG A 1 172 ? 6.323   -30.981 48.147  1 43.61  ? 164  ARG A NH2 1 
ATOM   1136 N  N   . PHE A 1 173 ? 8.631   -22.717 47.508  1 16.77  ? 165  PHE A N   1 
ATOM   1137 C  CA  . PHE A 1 173 ? 8.444   -21.306 47.205  1 18.958 ? 165  PHE A CA  1 
ATOM   1138 C  C   . PHE A 1 173 ? 7.106   -21.116 46.521  1 16.184 ? 165  PHE A C   1 
ATOM   1139 O  O   . PHE A 1 173 ? 6.882   -21.648 45.43   1 14.003 ? 165  PHE A O   1 
ATOM   1140 C  CB  . PHE A 1 173 ? 9.562   -20.749 46.298  1 17.88  ? 165  PHE A CB  1 
ATOM   1141 C  CG  . PHE A 1 173 ? 9.466   -19.261 46.036  1 15.748 ? 165  PHE A CG  1 
ATOM   1142 C  CD1 . PHE A 1 173 ? 9.531   -18.339 47.084  1 14.864 ? 165  PHE A CD1 1 
ATOM   1143 C  CD2 . PHE A 1 173 ? 9.273   -18.776 44.714  1 13.933 ? 165  PHE A CD2 1 
ATOM   1144 C  CE1 . PHE A 1 173 ? 9.387   -16.958 46.846  1 15.561 ? 165  PHE A CE1 1 
ATOM   1145 C  CE2 . PHE A 1 173 ? 9.122   -17.405 44.491  1 14.729 ? 165  PHE A CE2 1 
ATOM   1146 C  CZ  . PHE A 1 173 ? 9.208   -16.506 45.536  1 16.778 ? 165  PHE A CZ  1 
ATOM   1147 N  N   . LEU A 1 174 ? 6.28    -20.246 47.112  1 18.332 ? 166  LEU A N   1 
ATOM   1148 C  CA  . LEU A 1 174 ? 4.883   -20.116 46.722  1 15.349 ? 166  LEU A CA  1 
ATOM   1149 C  C   . LEU A 1 174 ? 4.563   -18.69  46.283  1 14.485 ? 166  LEU A C   1 
ATOM   1150 O  O   . LEU A 1 174 ? 4.897   -17.747 46.98   1 12.501 ? 166  LEU A O   1 
ATOM   1151 C  CB  . LEU A 1 174 ? 3.898   -20.487 47.831  1 15.965 ? 166  LEU A CB  1 
ATOM   1152 C  CG  . LEU A 1 174 ? 3.536   -21.96  48.075  1 16.586 ? 166  LEU A CG  1 
ATOM   1153 C  CD1 . LEU A 1 174 ? 4.7     -22.949 48.086  1 21.517 ? 166  LEU A CD1 1 
ATOM   1154 C  CD2 . LEU A 1 174 ? 2.918   -22.001 49.476  1 15.3   ? 166  LEU A CD2 1 
ATOM   1155 N  N   . ALA A 1 175 ? 3.797   -18.579 45.162  1 12.241 ? 167  ALA A N   1 
ATOM   1156 C  CA  . ALA A 1 175 ? 3.063   -17.381 44.783  1 13.309 ? 167  ALA A CA  1 
ATOM   1157 C  C   . ALA A 1 175 ? 1.59    -17.561 45.124  1 11.796 ? 167  ALA A C   1 
ATOM   1158 O  O   . ALA A 1 175 ? 0.963   -18.584 44.78   1 10.606 ? 167  ALA A O   1 
ATOM   1159 C  CB  . ALA A 1 175 ? 3.275   -17.165 43.249  1 12.558 ? 167  ALA A CB  1 
ATOM   1160 N  N   . MET A 1 176 ? 0.998   -16.515 45.736  1 11.431 ? 168  MET A N   1 
ATOM   1161 C  CA  . MET A 1 176 ? -0.272  -16.611 46.406  1 11.719 ? 168  MET A CA  1 
ATOM   1162 C  C   . MET A 1 176 ? -1.226  -15.52  45.91   1 10.828 ? 168  MET A C   1 
ATOM   1163 O  O   . MET A 1 176 ? -0.806  -14.413 45.541  1 11.661 ? 168  MET A O   1 
ATOM   1164 C  CB  . MET A 1 176 ? 0.006   -16.385 47.905  1 11.387 ? 168  MET A CB  1 
ATOM   1165 C  CG  . MET A 1 176 ? 0.837   -17.47  48.533  1 9.066  ? 168  MET A CG  1 
ATOM   1166 S  SD  . MET A 1 176 ? 1.033   -17.264 50.331  1 12.826 ? 168  MET A SD  1 
ATOM   1167 C  CE  . MET A 1 176 ? 2.188   -15.882 50.436  1 11.945 ? 168  MET A CE  1 
ATOM   1168 N  N   . LYS A 1 177 ? -2.492  -15.875 45.823  1 11.664 ? 169  LYS A N   1 
ATOM   1169 C  CA  . LYS A 1 177 ? -3.618  -14.96  45.686  1 11.686 ? 169  LYS A CA  1 
ATOM   1170 C  C   . LYS A 1 177 ? -4.813  -15.615 46.392  1 11.261 ? 169  LYS A C   1 
ATOM   1171 O  O   . LYS A 1 177 ? -5.072  -16.791 46.189  1 10.305 ? 169  LYS A O   1 
ATOM   1172 C  CB  . LYS A 1 177 ? -3.829  -14.676 44.165  1 9.525  ? 169  LYS A CB  1 
ATOM   1173 C  CG  . LYS A 1 177 ? -4.737  -13.398 44.027  1 13.098 ? 169  LYS A CG  1 
ATOM   1174 C  CD  . LYS A 1 177 ? -5.122  -13.138 42.572  1 13.22  ? 169  LYS A CD  1 
ATOM   1175 C  CE  . LYS A 1 177 ? -6.065  -11.892 42.418  1 15.109 ? 169  LYS A CE  1 
ATOM   1176 N  NZ  . LYS A 1 177 ? -5.261  -10.731 42.935  1 11.944 ? 169  LYS A NZ  1 
ATOM   1177 N  N   . GLU A 1 178 ? -5.614  -14.799 47.101  1 11.414 ? 170  GLU A N   1 
ATOM   1178 C  CA  . GLU A 1 178 ? -6.566  -15.296 48.067  1 12.616 ? 170  GLU A CA  1 
ATOM   1179 C  C   . GLU A 1 178 ? -7.766  -16.019 47.448  1 11.532 ? 170  GLU A C   1 
ATOM   1180 O  O   . GLU A 1 178 ? -8.458  -16.654 48.236  1 12.575 ? 170  GLU A O   1 
ATOM   1181 C  CB  . GLU A 1 178 ? -6.991  -14.22  49.07   1 13.029 ? 170  GLU A CB  1 
ATOM   1182 C  CG  . GLU A 1 178 ? -7.893  -13.159 48.442  1 11.718 ? 170  GLU A CG  1 
ATOM   1183 C  CD  . GLU A 1 178 ? -7.719  -11.888 49.235  1 14.196 ? 170  GLU A CD  1 
ATOM   1184 O  OE1 . GLU A 1 178 ? -6.593  -11.297 49.272  1 15.485 ? 170  GLU A OE1 1 
ATOM   1185 O  OE2 . GLU A 1 178 ? -8.732  -11.562 49.872  1 14.825 ? 170  GLU A OE2 1 
ATOM   1186 N  N   . ASN A 1 179 ? -7.973  -15.939 46.08   1 10.862 ? 171  ASN A N   1 
ATOM   1187 C  CA  . ASN A 1 179 ? -9.058  -16.631 45.422  1 10.21  ? 171  ASN A CA  1 
ATOM   1188 C  C   . ASN A 1 179 ? -8.66   -18.052 44.974  1 10.496 ? 171  ASN A C   1 
ATOM   1189 O  O   . ASN A 1 179 ? -9.421  -18.713 44.256  1 13.833 ? 171  ASN A O   1 
ATOM   1190 C  CB  . ASN A 1 179 ? -9.635  -15.823 44.242  1 10.881 ? 171  ASN A CB  1 
ATOM   1191 C  CG  . ASN A 1 179 ? -8.608  -15.518 43.194  1 11.647 ? 171  ASN A CG  1 
ATOM   1192 O  OD1 . ASN A 1 179 ? -7.419  -15.497 43.481  1 13.195 ? 171  ASN A OD1 1 
ATOM   1193 N  ND2 . ASN A 1 179 ? -9.021  -15.284 41.962  1 13.252 ? 171  ASN A ND2 1 
ATOM   1194 N  N   . GLY A 1 180 ? -7.455  -18.511 45.311  1 9.725  ? 172  GLY A N   1 
ATOM   1195 C  CA  . GLY A 1 180 ? -7.074  -19.903 45.029  1 9.975  ? 172  GLY A CA  1 
ATOM   1196 C  C   . GLY A 1 180 ? -6.024  -20.419 45.993  1 11.261 ? 172  GLY A C   1 
ATOM   1197 O  O   . GLY A 1 180 ? -5.54   -19.71  46.842  1 13.555 ? 172  GLY A O   1 
ATOM   1198 N  N   . ASN A 1 181 ? -5.644  -21.694 45.851  1 12.924 ? 173  ASN A N   1 
ATOM   1199 C  CA  . ASN A 1 181 ? -4.439  -22.188 46.472  1 11.761 ? 173  ASN A CA  1 
ATOM   1200 C  C   . ASN A 1 181 ? -3.244  -21.563 45.764  1 11.65  ? 173  ASN A C   1 
ATOM   1201 O  O   . ASN A 1 181 ? -3.348  -21.055 44.631  1 10.893 ? 173  ASN A O   1 
ATOM   1202 C  CB  . ASN A 1 181 ? -4.45   -23.711 46.581  1 9.933  ? 173  ASN A CB  1 
ATOM   1203 C  CG  . ASN A 1 181 ? -5.204  -24.12  47.834  1 10.481 ? 173  ASN A CG  1 
ATOM   1204 O  OD1 . ASN A 1 181 ? -4.746  -23.859 48.961  1 11.423 ? 173  ASN A OD1 1 
ATOM   1205 N  ND2 . ASN A 1 181 ? -6.398  -24.739 47.713  1 14.305 ? 173  ASN A ND2 1 
ATOM   1206 N  N   . ALA A 1 182 ? -2.079  -21.744 46.387  1 12.818 ? 174  ALA A N   1 
ATOM   1207 C  CA  . ALA A 1 182 ? -0.832  -21.182 45.893  1 12.186 ? 174  ALA A CA  1 
ATOM   1208 C  C   . ALA A 1 182 ? -0.31   -21.99  44.705  1 13.48  ? 174  ALA A C   1 
ATOM   1209 O  O   . ALA A 1 182 ? -0.642  -23.175 44.555  1 13.198 ? 174  ALA A O   1 
ATOM   1210 C  CB  . ALA A 1 182 ? 0.175   -21.241 47.043  1 11.138 ? 174  ALA A CB  1 
ATOM   1211 N  N   . TYR A 1 183 ? 0.518   -21.326 43.889  1 13.912 ? 175  TYR A N   1 
ATOM   1212 C  CA  . TYR A 1 183 ? 1.328   -22     42.891  1 14.924 ? 175  TYR A CA  1 
ATOM   1213 C  C   . TYR A 1 183 ? 2.765   -22.074 43.41   1 14.084 ? 175  TYR A C   1 
ATOM   1214 O  O   . TYR A 1 183 ? 3.327   -21.073 43.866  1 15.409 ? 175  TYR A O   1 
ATOM   1215 C  CB  . TYR A 1 183 ? 1.244   -21.294 41.547  1 12.08  ? 175  TYR A CB  1 
ATOM   1216 C  CG  . TYR A 1 183 ? -0.073  -21.401 40.811  1 13.07  ? 175  TYR A CG  1 
ATOM   1217 C  CD1 . TYR A 1 183 ? -1.117  -20.498 41.032  1 11.741 ? 175  TYR A CD1 1 
ATOM   1218 C  CD2 . TYR A 1 183 ? -0.229  -22.388 39.842  1 12.496 ? 175  TYR A CD2 1 
ATOM   1219 C  CE1 . TYR A 1 183 ? -2.295  -20.612 40.282  1 13.891 ? 175  TYR A CE1 1 
ATOM   1220 C  CE2 . TYR A 1 183 ? -1.375  -22.512 39.071  1 11.543 ? 175  TYR A CE2 1 
ATOM   1221 C  CZ  . TYR A 1 183 ? -2.41   -21.618 39.318  1 11.221 ? 175  TYR A CZ  1 
ATOM   1222 O  OH  . TYR A 1 183 ? -3.527  -21.765 38.564  1 10.711 ? 175  TYR A OH  1 
ATOM   1223 N  N   . GLU A 1 184 ? 3.399   -23.242 43.226  1 11.161 ? 176  GLU A N   1 
ATOM   1224 C  CA  . GLU A 1 184 ? 4.818   -23.322 43.535  1 13.84  ? 176  GLU A CA  1 
ATOM   1225 C  C   . GLU A 1 184 ? 5.666   -22.961 42.323  1 16.718 ? 176  GLU A C   1 
ATOM   1226 O  O   . GLU A 1 184 ? 5.279   -23.207 41.156  1 15.83  ? 176  GLU A O   1 
ATOM   1227 C  CB  . GLU A 1 184 ? 5.109   -24.767 43.997  1 17.726 ? 176  GLU A CB  1 
ATOM   1228 C  CG  . GLU A 1 184 ? 6.528   -24.972 44.542  1 17.058 ? 176  GLU A CG  1 
ATOM   1229 C  CD  . GLU A 1 184 ? 6.782   -26.419 44.974  1 20.464 ? 176  GLU A CD  1 
ATOM   1230 O  OE1 . GLU A 1 184 ? 5.908   -27.332 44.842  1 24.325 ? 176  GLU A OE1 1 
ATOM   1231 O  OE2 . GLU A 1 184 ? 7.889   -26.597 45.45   1 22.059 ? 176  GLU A OE2 1 
ATOM   1232 N  N   . MET A 1 185 ? 6.822   -22.362 42.61   1 15.572 ? 177  MET A N   1 
ATOM   1233 C  CA  . MET A 1 185 ? 7.795   -22.019 41.584  1 16.995 ? 177  MET A CA  1 
ATOM   1234 C  C   . MET A 1 185 ? 9.157   -22.445 42.091  1 15.852 ? 177  MET A C   1 
ATOM   1235 O  O   . MET A 1 185 ? 9.451   -22.516 43.314  1 13.483 ? 177  MET A O   1 
ATOM   1236 C  CB  . MET A 1 185 ? 7.844   -20.49  41.403  1 15.033 ? 177  MET A CB  1 
ATOM   1237 C  CG  . MET A 1 185 ? 6.464   -19.824 41.288  1 16.309 ? 177  MET A CG  1 
ATOM   1238 S  SD  . MET A 1 185 ? 6.555   -18.009 41.122  1 17.434 ? 177  MET A SD  1 
ATOM   1239 C  CE  . MET A 1 185 ? 6.861   -17.65  39.377  1 14.889 ? 177  MET A CE  1 
ATOM   1240 N  N   . ASP A 1 186 ? 10.001  -22.722 41.133  1 13.979 ? 178  ASP A N   1 
ATOM   1241 C  CA  . ASP A 1 186 ? 11.412  -22.926 41.425  1 16.907 ? 178  ASP A CA  1 
ATOM   1242 C  C   . ASP A 1 186 ? 12.019  -21.623 41.933  1 18.152 ? 178  ASP A C   1 
ATOM   1243 O  O   . ASP A 1 186 ? 11.789  -20.607 41.31   1 15.72  ? 178  ASP A O   1 
ATOM   1244 C  CB  . ASP A 1 186 ? 12.163  -23.442 40.2    1 18.399 ? 178  ASP A CB  1 
ATOM   1245 C  CG  . ASP A 1 186 ? 13.604  -23.795 40.529  1 18.556 ? 178  ASP A CG  1 
ATOM   1246 O  OD1 . ASP A 1 186 ? 14.414  -22.877 40.571  1 15.607 ? 178  ASP A OD1 1 
ATOM   1247 O  OD2 . ASP A 1 186 ? 13.873  -25     40.78   1 18.916 ? 178  ASP A OD2 1 
ATOM   1248 N  N   . PRO A 1 187 ? 12.757  -21.557 43.076  1 17.403 ? 179  PRO A N   1 
ATOM   1249 C  CA  . PRO A 1 187 ? 13.212  -20.267 43.582  1 19.497 ? 179  PRO A CA  1 
ATOM   1250 C  C   . PRO A 1 187 ? 14.421  -19.647 42.858  1 16.14  ? 179  PRO A C   1 
ATOM   1251 O  O   . PRO A 1 187 ? 14.75   -18.476 43.092  1 18.044 ? 179  PRO A O   1 
ATOM   1252 C  CB  . PRO A 1 187 ? 13.482  -20.557 45.055  1 21.25  ? 179  PRO A CB  1 
ATOM   1253 C  CG  . PRO A 1 187 ? 13.991  -21.978 44.97   1 15.995 ? 179  PRO A CG  1 
ATOM   1254 C  CD  . PRO A 1 187 ? 13.113  -22.667 43.995  1 15.802 ? 179  PRO A CD  1 
ATOM   1255 N  N   . HIS A 1 188 ? 14.959  -20.367 41.872  1 15.555 ? 180  HIS A N   1 
ATOM   1256 C  CA  . HIS A 1 188 ? 16.141  -19.899 41.183  1 16.625 ? 180  HIS A CA  1 
ATOM   1257 C  C   . HIS A 1 188 ? 15.796  -19.525 39.732  1 16.386 ? 180  HIS A C   1 
ATOM   1258 O  O   . HIS A 1 188 ? 16.257  -18.489 39.277  1 18.629 ? 180  HIS A O   1 
ATOM   1259 C  CB  . HIS A 1 188 ? 17.253  -20.977 41.187  1 16.04  ? 180  HIS A CB  1 
ATOM   1260 C  CG  . HIS A 1 188 ? 17.465  -21.544 42.563  1 15.582 ? 180  HIS A CG  1 
ATOM   1261 N  ND1 . HIS A 1 188 ? 17.994  -20.845 43.627  1 17.312 ? 180  HIS A ND1 1 
ATOM   1262 C  CD2 . HIS A 1 188 ? 17.199  -22.778 43.014  1 16.426 ? 180  HIS A CD2 1 
ATOM   1263 C  CE1 . HIS A 1 188 ? 18.018  -21.638 44.691  1 17.25  ? 180  HIS A CE1 1 
ATOM   1264 N  NE2 . HIS A 1 188 ? 17.528  -22.82  44.337  1 17.719 ? 180  HIS A NE2 1 
ATOM   1265 N  N   . THR A 1 189 ? 15.023  -20.374 39.054  1 16.842 ? 181  THR A N   1 
ATOM   1266 C  CA  . THR A 1 189 ? 14.662  -20.154 37.651  1 15.559 ? 181  THR A CA  1 
ATOM   1267 C  C   . THR A 1 189 ? 13.286  -19.474 37.595  1 15.419 ? 181  THR A C   1 
ATOM   1268 O  O   . THR A 1 189 ? 12.886  -18.999 36.523  1 15.563 ? 181  THR A O   1 
ATOM   1269 C  CB  . THR A 1 189 ? 14.646  -21.433 36.803  1 17.673 ? 181  THR A CB  1 
ATOM   1270 O  OG1 . THR A 1 189 ? 13.603  -22.255 37.332  1 16.626 ? 181  THR A OG1 1 
ATOM   1271 C  CG2 . THR A 1 189 ? 15.949  -22.22  36.868  1 20.719 ? 181  THR A CG2 1 
ATOM   1272 N  N   . LEU A 1 190 ? 12.549  -19.498 38.726  1 14.175 ? 182  LEU A N   1 
ATOM   1273 C  CA  . LEU A 1 190 ? 11.137  -19.087 38.818  1 14.258 ? 182  LEU A CA  1 
ATOM   1274 C  C   . LEU A 1 190 ? 10.22   -19.884 37.872  1 12.761 ? 182  LEU A C   1 
ATOM   1275 O  O   . LEU A 1 190 ? 9.091   -19.477 37.648  1 15.008 ? 182  LEU A O   1 
ATOM   1276 C  CB  . LEU A 1 190 ? 10.963  -17.562 38.659  1 13.478 ? 182  LEU A CB  1 
ATOM   1277 C  CG  . LEU A 1 190 ? 11.749  -16.716 39.654  1 13.133 ? 182  LEU A CG  1 
ATOM   1278 C  CD1 . LEU A 1 190 ? 11.599  -15.215 39.238  1 12.401 ? 182  LEU A CD1 1 
ATOM   1279 C  CD2 . LEU A 1 190 ? 11.106  -17.026 41.057  1 13.353 ? 182  LEU A CD2 1 
ATOM   1280 N  N   . LYS A 1 191 ? 10.656  -21.068 37.387  1 13.347 ? 183  LYS A N   1 
ATOM   1281 C  CA  . LYS A 1 191 ? 9.753   -21.97  36.672  1 15.075 ? 183  LYS A CA  1 
ATOM   1282 C  C   . LYS A 1 191 ? 8.61    -22.433 37.588  1 15.263 ? 183  LYS A C   1 
ATOM   1283 O  O   . LYS A 1 191 ? 8.879   -22.702 38.781  1 13.073 ? 183  LYS A O   1 
ATOM   1284 C  CB  . LYS A 1 191 ? 10.567  -23.162 36.131  1 16.613 ? 183  LYS A CB  1 
ATOM   1285 C  CG  . LYS A 1 191 ? 9.648   -24.038 35.272  1 21.606 ? 183  LYS A CG  1 
ATOM   1286 C  CD  . LYS A 1 191 ? 10.447  -25.11  34.499  1 26.611 ? 183  LYS A CD  1 
ATOM   1287 C  CE  . LYS A 1 191 ? 9.615   -26.002 33.615  1 30.602 ? 183  LYS A CE  1 
ATOM   1288 N  NZ  . LYS A 1 191 ? 9.025   -25.396 32.408  1 26.058 ? 183  LYS A NZ  1 
ATOM   1289 N  N   . THR A 1 192 ? 7.356   -22.419 37.05   1 12.743 ? 184  THR A N   1 
ATOM   1290 C  CA  . THR A 1 192 ? 6.177   -22.949 37.745  1 12.462 ? 184  THR A CA  1 
ATOM   1291 C  C   . THR A 1 192 ? 6.263   -24.486 37.819  1 11.116 ? 184  THR A C   1 
ATOM   1292 O  O   . THR A 1 192 ? 6.497   -25.096 36.811  1 9.36   ? 184  THR A O   1 
ATOM   1293 C  CB  . THR A 1 192 ? 4.879   -22.421 37.156  1 14.203 ? 184  THR A CB  1 
ATOM   1294 O  OG1 . THR A 1 192 ? 5.019   -20.99  37.249  1 15.607 ? 184  THR A OG1 1 
ATOM   1295 C  CG2 . THR A 1 192 ? 3.623   -22.945 37.841  1 18.627 ? 184  THR A CG2 1 
ATOM   1296 N  N   . LEU A 1 193 ? 6.134   -25.014 39.032  1 9.764  ? 185  LEU A N   1 
ATOM   1297 C  CA  . LEU A 1 193 ? 6.27    -26.453 39.317  1 14.007 ? 185  LEU A CA  1 
ATOM   1298 C  C   . LEU A 1 193 ? 4.898   -27.112 39.57   1 15.91  ? 185  LEU A C   1 
ATOM   1299 O  O   . LEU A 1 193 ? 4.779   -28.339 39.423  1 15.762 ? 185  LEU A O   1 
ATOM   1300 C  CB  . LEU A 1 193 ? 7.14    -26.611 40.575  1 14.91  ? 185  LEU A CB  1 
ATOM   1301 C  CG  . LEU A 1 193 ? 8.537   -25.973 40.497  1 19.143 ? 185  LEU A CG  1 
ATOM   1302 C  CD1 . LEU A 1 193 ? 9.213   -26.236 41.817  1 20.366 ? 185  LEU A CD1 1 
ATOM   1303 C  CD2 . LEU A 1 193 ? 9.356   -26.48  39.312  1 19.364 ? 185  LEU A CD2 1 
ATOM   1304 N  N   . GLY A 1 194 ? 3.855   -26.356 39.973  1 17.385 ? 186  GLY A N   1 
ATOM   1305 C  CA  . GLY A 1 194 ? 2.633   -27.02  40.428  1 18.818 ? 186  GLY A CA  1 
ATOM   1306 C  C   . GLY A 1 194 ? 1.701   -26.094 41.18   1 16.175 ? 186  GLY A C   1 
ATOM   1307 O  O   . GLY A 1 194 ? 2.072   -24.954 41.424  1 16.773 ? 186  GLY A O   1 
ATOM   1308 N  N   . TYR A 1 195 ? 0.488   -26.587 41.474  1 14.398 ? 187  TYR A N   1 
ATOM   1309 C  CA  . TYR A 1 195 ? -0.58   -25.903 42.226  1 12.766 ? 187  TYR A CA  1 
ATOM   1310 C  C   . TYR A 1 195 ? -0.91   -26.667 43.505  1 12.606 ? 187  TYR A C   1 
ATOM   1311 O  O   . TYR A 1 195 ? -0.915  -27.92  43.518  1 12.73  ? 187  TYR A O   1 
ATOM   1312 C  CB  . TYR A 1 195 ? -1.792  -25.873 41.298  1 13.445 ? 187  TYR A CB  1 
ATOM   1313 C  CG  . TYR A 1 195 ? -3.043  -25.289 41.939  1 11.533 ? 187  TYR A CG  1 
ATOM   1314 C  CD1 . TYR A 1 195 ? -3.215  -23.907 42.059  1 11.982 ? 187  TYR A CD1 1 
ATOM   1315 C  CD2 . TYR A 1 195 ? -4.025  -26.134 42.466  1 14.496 ? 187  TYR A CD2 1 
ATOM   1316 C  CE1 . TYR A 1 195 ? -4.369  -23.378 42.639  1 12.633 ? 187  TYR A CE1 1 
ATOM   1317 C  CE2 . TYR A 1 195 ? -5.176  -25.617 43.04   1 12.208 ? 187  TYR A CE2 1 
ATOM   1318 C  CZ  . TYR A 1 195 ? -5.336  -24.234 43.151  1 13.538 ? 187  TYR A CZ  1 
ATOM   1319 O  OH  . TYR A 1 195 ? -6.461  -23.705 43.756  1 12.015 ? 187  TYR A OH  1 
ATOM   1320 N  N   . ASN A 1 196 ? -1.15   -25.904 44.575  1 12.098 ? 188  ASN A N   1 
ATOM   1321 C  CA  . ASN A 1 196 ? -1.515  -26.417 45.892  1 13.742 ? 188  ASN A CA  1 
ATOM   1322 C  C   . ASN A 1 196 ? -0.537  -27.488 46.363  1 13.589 ? 188  ASN A C   1 
ATOM   1323 O  O   . ASN A 1 196 ? -0.93   -28.618 46.68   1 14.76  ? 188  ASN A O   1 
ATOM   1324 C  CB  . ASN A 1 196 ? -2.974  -26.943 45.833  1 9.656  ? 188  ASN A CB  1 
ATOM   1325 C  CG  . ASN A 1 196 ? -3.54   -27.211 47.202  1 10.673 ? 188  ASN A CG  1 
ATOM   1326 O  OD1 . ASN A 1 196 ? -3.116  -26.667 48.215  1 10.781 ? 188  ASN A OD1 1 
ATOM   1327 N  ND2 . ASN A 1 196 ? -4.634  -27.954 47.263  1 15.823 ? 188  ASN A ND2 1 
ATOM   1328 N  N   . PRO A 1 197 ? 0.763   -27.126 46.558  1 14.806 ? 189  PRO A N   1 
ATOM   1329 C  CA  . PRO A 1 197 ? 1.759   -28.051 47.026  1 18.324 ? 189  PRO A CA  1 
ATOM   1330 C  C   . PRO A 1 197 ? 1.522   -28.655 48.402  1 18.634 ? 189  PRO A C   1 
ATOM   1331 O  O   . PRO A 1 197 ? 1.997   -29.768 48.622  1 21.509 ? 189  PRO A O   1 
ATOM   1332 C  CB  . PRO A 1 197 ? 3.026   -27.176 47.09   1 15.478 ? 189  PRO A CB  1 
ATOM   1333 C  CG  . PRO A 1 197 ? 2.507   -25.764 47.29   1 15.85  ? 189  PRO A CG  1 
ATOM   1334 C  CD  . PRO A 1 197 ? 1.347   -25.779 46.345  1 16.354 ? 189  PRO A CD  1 
ATOM   1335 N  N   . PHE A 1 198 ? 0.881   -27.904 49.302  1 16.686 ? 190  PHE A N   1 
ATOM   1336 C  CA  . PHE A 1 198 ? 0.547   -28.451 50.624  1 16.239 ? 190  PHE A CA  1 
ATOM   1337 C  C   . PHE A 1 198 ? -0.804  -29.207 50.652  1 19.717 ? 190  PHE A C   1 
ATOM   1338 O  O   . PHE A 1 198 ? -1.254  -29.689 51.729  1 17.465 ? 190  PHE A O   1 
ATOM   1339 C  CB  . PHE A 1 198 ? 0.666   -27.392 51.716  1 14.499 ? 190  PHE A CB  1 
ATOM   1340 C  CG  . PHE A 1 198 ? 2.066   -26.799 51.828  1 17.72  ? 190  PHE A CG  1 
ATOM   1341 C  CD1 . PHE A 1 198 ? 3.187   -27.634 52      1 15.155 ? 190  PHE A CD1 1 
ATOM   1342 C  CD2 . PHE A 1 198 ? 2.263   -25.422 51.694  1 18.187 ? 190  PHE A CD2 1 
ATOM   1343 C  CE1 . PHE A 1 198 ? 4.456   -27.079 52.045  1 13.88  ? 190  PHE A CE1 1 
ATOM   1344 C  CE2 . PHE A 1 198 ? 3.533   -24.855 51.793  1 17.121 ? 190  PHE A CE2 1 
ATOM   1345 C  CZ  . PHE A 1 198 ? 4.626   -25.703 51.901  1 17.291 ? 190  PHE A CZ  1 
ATOM   1346 N  N   . ASN A 1 199 ? -1.45   -29.352 49.486  1 13.793 ? 191  ASN A N   1 
ATOM   1347 C  CA  . ASN A 1 199 ? -2.68   -30.135 49.368  1 19.803 ? 191  ASN A CA  1 
ATOM   1348 C  C   . ASN A 1 199 ? -3.769  -29.752 50.384  1 18.165 ? 191  ASN A C   1 
ATOM   1349 O  O   . ASN A 1 199 ? -4.449  -30.603 50.952  1 15.862 ? 191  ASN A O   1 
ATOM   1350 C  CB  . ASN A 1 199 ? -2.362  -31.636 49.385  1 21.363 ? 191  ASN A CB  1 
ATOM   1351 C  CG  . ASN A 1 199 ? -3.503  -32.476 48.861  1 27.762 ? 191  ASN A CG  1 
ATOM   1352 O  OD1 . ASN A 1 199 ? -4.162  -32.111 47.863  1 25.723 ? 191  ASN A OD1 1 
ATOM   1353 N  ND2 . ASN A 1 199 ? -3.791  -33.576 49.557  1 29.512 ? 191  ASN A ND2 1 
ATOM   1354 N  N   . LEU A 1 200 ? -3.967  -28.449 50.582  1 14.803 ? 192  LEU A N   1 
ATOM   1355 C  CA  . LEU A 1 200 ? -5.054  -27.908 51.379  1 12.924 ? 192  LEU A CA  1 
ATOM   1356 C  C   . LEU A 1 200 ? -6.421  -28.33  50.821  1 13.487 ? 192  LEU A C   1 
ATOM   1357 O  O   . LEU A 1 200 ? -6.644  -28.376 49.617  1 12.264 ? 192  LEU A O   1 
ATOM   1358 C  CB  . LEU A 1 200 ? -4.913  -26.415 51.673  1 12.316 ? 192  LEU A CB  1 
ATOM   1359 C  CG  . LEU A 1 200 ? -3.514  -25.944 52.128  1 10.704 ? 192  LEU A CG  1 
ATOM   1360 C  CD1 . LEU A 1 200 ? -3.793  -24.426 52.28   1 12.798 ? 192  LEU A CD1 1 
ATOM   1361 C  CD2 . LEU A 1 200 ? -3.043  -26.547 53.45   1 12.45  ? 192  LEU A CD2 1 
ATOM   1362 N  N   . PRO A 1 201 ? -7.348  -28.719 51.702  1 15.044 ? 193  PRO A N   1 
ATOM   1363 C  CA  . PRO A 1 201 ? -8.69   -29.133 51.281  1 14.282 ? 193  PRO A CA  1 
ATOM   1364 C  C   . PRO A 1 201 ? -9.633  -28.001 50.874  1 15.752 ? 193  PRO A C   1 
ATOM   1365 O  O   . PRO A 1 201 ? -10.703 -28.251 50.293  1 16.921 ? 193  PRO A O   1 
ATOM   1366 C  CB  . PRO A 1 201 ? -9.133  -29.957 52.503  1 14.018 ? 193  PRO A CB  1 
ATOM   1367 C  CG  . PRO A 1 201 ? -8.461  -29.292 53.674  1 15.051 ? 193  PRO A CG  1 
ATOM   1368 C  CD  . PRO A 1 201 ? -7.11   -28.867 53.16   1 14.942 ? 193  PRO A CD  1 
ATOM   1369 N  N   . SER A 1 202 ? -9.256  -26.744 51.208  1 14.134 ? 194  SER A N   1 
ATOM   1370 C  CA  . SER A 1 202 ? -10.08  -25.591 50.862  1 14.846 ? 194  SER A CA  1 
ATOM   1371 C  C   . SER A 1 202 ? -9.818  -25.283 49.367  1 13.067 ? 194  SER A C   1 
ATOM   1372 O  O   . SER A 1 202 ? -8.907  -25.824 48.774  1 14.492 ? 194  SER A O   1 
ATOM   1373 C  CB  . SER A 1 202 ? -9.679  -24.479 51.792  1 15.884 ? 194  SER A CB  1 
ATOM   1374 O  OG  . SER A 1 202 ? -8.256  -24.337 51.744  1 17.046 ? 194  SER A OG  1 
ATOM   1375 N  N   . LYS A 1 203 ? -10.681 -24.509 48.734  1 14.001 ? 195  LYS A N   1 
ATOM   1376 C  CA  . LYS A 1 203 ? -10.493 -24.093 47.347  1 10.858 ? 195  LYS A CA  1 
ATOM   1377 C  C   . LYS A 1 203 ? -9.628  -22.814 47.318  1 9.749  ? 195  LYS A C   1 
ATOM   1378 O  O   . LYS A 1 203 ? -9.221  -22.396 46.195  1 8.811  ? 195  LYS A O   1 
ATOM   1379 C  CB  . LYS A 1 203 ? -11.852 -23.846 46.737  1 14.057 ? 195  LYS A CB  1 
ATOM   1380 C  CG  . LYS A 1 203 ? -12.734 -25.091 46.585  1 17.005 ? 195  LYS A CG  1 
ATOM   1381 C  CD  . LYS A 1 203 ? -13.968 -24.499 45.902  1 19.296 ? 195  LYS A CD  1 
ATOM   1382 C  CE  . LYS A 1 203 ? -15.091 -25.512 45.724  1 20.243 ? 195  LYS A CE  1 
ATOM   1383 N  NZ  . LYS A 1 203 ? -15.079 -26.012 44.36   1 23.906 ? 195  LYS A NZ  1 
ATOM   1384 N  N   . THR A 1 204 ? -9.308  -22.257 48.526  1 8.603  ? 196  THR A N   1 
ATOM   1385 C  CA  . THR A 1 204 ? -8.508  -21.023 48.562  1 10.204 ? 196  THR A CA  1 
ATOM   1386 C  C   . THR A 1 204 ? -7.481  -21.084 49.698  1 10.988 ? 196  THR A C   1 
ATOM   1387 O  O   . THR A 1 204 ? -7.633  -21.851 50.686  1 10.181 ? 196  THR A O   1 
ATOM   1388 C  CB  . THR A 1 204 ? -9.466  -19.854 48.852  1 9.713  ? 196  THR A CB  1 
ATOM   1389 O  OG1 . THR A 1 204 ? -10.054 -20.029 50.146  1 15.189 ? 196  THR A OG1 1 
ATOM   1390 C  CG2 . THR A 1 204 ? -10.532 -19.644 47.781  1 12.312 ? 196  THR A CG2 1 
ATOM   1391 N  N   . MET A 1 205 ? -6.446  -20.217 49.558  1 10.97  ? 197  MET A N   1 
ATOM   1392 C  CA  . MET A 1 205 ? -5.556  -19.956 50.654  1 11.322 ? 197  MET A CA  1 
ATOM   1393 C  C   . MET A 1 205 ? -5.3    -18.448 50.642  1 10.583 ? 197  MET A C   1 
ATOM   1394 O  O   . MET A 1 205 ? -5.135  -17.837 49.582  1 8.918  ? 197  MET A O   1 
ATOM   1395 C  CB  . MET A 1 205 ? -4.21   -20.705 50.479  1 12.166 ? 197  MET A CB  1 
ATOM   1396 C  CG  . MET A 1 205 ? -3.347  -20.528 51.756  1 12.054 ? 197  MET A CG  1 
ATOM   1397 S  SD  . MET A 1 205 ? -1.702  -21.279 51.611  1 14.346 ? 197  MET A SD  1 
ATOM   1398 C  CE  . MET A 1 205 ? -0.705  -20.025 50.791  1 14.525 ? 197  MET A CE  1 
ATOM   1399 N  N   . THR A 1 206 ? -5.263  -17.871 51.854  1 9.095  ? 198  THR A N   1 
ATOM   1400 C  CA  . THR A 1 206 ? -4.899  -16.46  52.006  1 10.265 ? 198  THR A CA  1 
ATOM   1401 C  C   . THR A 1 206 ? -3.564  -16.194 51.354  1 11.585 ? 198  THR A C   1 
ATOM   1402 O  O   . THR A 1 206 ? -2.694  -17.079 51.28   1 13.332 ? 198  THR A O   1 
ATOM   1403 C  CB  . THR A 1 206 ? -4.894  -16.112 53.522  1 12.169 ? 198  THR A CB  1 
ATOM   1404 O  OG1 . THR A 1 206 ? -4.561  -14.727 53.672  1 12.961 ? 198  THR A OG1 1 
ATOM   1405 C  CG2 . THR A 1 206 ? -3.73   -16.757 54.236  1 12.812 ? 198  THR A CG2 1 
ATOM   1406 N  N   . ALA A 1 207 ? -3.357  -14.936 50.895  1 11.994 ? 199  ALA A N   1 
ATOM   1407 C  CA  . ALA A 1 207 ? -2.001  -14.543 50.476  1 11.444 ? 199  ALA A CA  1 
ATOM   1408 C  C   . ALA A 1 207 ? -1.23   -13.969 51.644  1 12.155 ? 199  ALA A C   1 
ATOM   1409 O  O   . ALA A 1 207 ? -0.111  -13.514 51.474  1 12.454 ? 199  ALA A O   1 
ATOM   1410 C  CB  . ALA A 1 207 ? -2.004  -13.594 49.325  1 11.689 ? 199  ALA A CB  1 
ATOM   1411 N  N   . HIS A 1 208 ? -1.827  -14.032 52.853  1 13.121 ? 200  HIS A N   1 
ATOM   1412 C  CA  . HIS A 1 208 ? -1.184  -13.508 54.029  1 12.845 ? 200  HIS A CA  1 
ATOM   1413 C  C   . HIS A 1 208 ? -1.112  -14.548 55.135  1 14.166 ? 200  HIS A C   1 
ATOM   1414 O  O   . HIS A 1 208 ? -1.49   -14.24  56.271  1 13.194 ? 200  HIS A O   1 
ATOM   1415 C  CB  . HIS A 1 208 ? -1.95   -12.242 54.501  1 13.104 ? 200  HIS A CB  1 
ATOM   1416 C  CG  . HIS A 1 208 ? -1.621  -11.022 53.708  1 10.617 ? 200  HIS A CG  1 
ATOM   1417 N  ND1 . HIS A 1 208 ? -0.317  -10.619 53.681  1 9.049  ? 200  HIS A ND1 1 
ATOM   1418 C  CD2 . HIS A 1 208 ? -2.265  -10.243 52.79   1 10.722 ? 200  HIS A CD2 1 
ATOM   1419 C  CE1 . HIS A 1 208 ? -0.181  -9.554  52.909  1 9.156  ? 200  HIS A CE1 1 
ATOM   1420 N  NE2 . HIS A 1 208 ? -1.394  -9.272  52.39   1 11.324 ? 200  HIS A NE2 1 
ATOM   1421 N  N   . PRO A 1 209 ? -0.516  -15.757 54.893  1 15.017 ? 201  PRO A N   1 
ATOM   1422 C  CA  . PRO A 1 209 ? -0.15   -16.661 55.967  1 15.171 ? 201  PRO A CA  1 
ATOM   1423 C  C   . PRO A 1 209 ? 1.036   -16.133 56.746  1 15.433 ? 201  PRO A C   1 
ATOM   1424 O  O   . PRO A 1 209 ? 1.771   -15.272 56.281  1 12.129 ? 201  PRO A O   1 
ATOM   1425 C  CB  . PRO A 1 209 ? 0.094   -17.952 55.2    1 17.825 ? 201  PRO A CB  1 
ATOM   1426 C  CG  . PRO A 1 209 ? 0.778   -17.496 53.947  1 14.858 ? 201  PRO A CG  1 
ATOM   1427 C  CD  . PRO A 1 209 ? -0.108  -16.329 53.579  1 13.513 ? 201  PRO A CD  1 
ATOM   1428 N  N   . LYS A 1 210 ? 1.048   -16.518 57.996  1 14.324 ? 202  LYS A N   1 
ATOM   1429 C  CA  . LYS A 1 210 ? 2.097   -16.07  58.886  1 16.671 ? 202  LYS A CA  1 
ATOM   1430 C  C   . LYS A 1 210 ? 2.972   -17.255 59.332  1 14.923 ? 202  LYS A C   1 
ATOM   1431 O  O   . LYS A 1 210 ? 2.474   -18.291 59.742  1 15.105 ? 202  LYS A O   1 
ATOM   1432 C  CB  . LYS A 1 210 ? 1.451   -15.355 60.072  1 15.997 ? 202  LYS A CB  1 
ATOM   1433 C  CG  . LYS A 1 210 ? 0.488   -14.222 59.801  1 17.162 ? 202  LYS A CG  1 
ATOM   1434 C  CD  . LYS A 1 210 ? 1.027   -13.028 58.98   1 16.625 ? 202  LYS A CD  1 
ATOM   1435 C  CE  . LYS A 1 210 ? -0.181  -12.308 58.454  1 15.149 ? 202  LYS A CE  1 
ATOM   1436 N  NZ  . LYS A 1 210 ? 0.162   -10.995 57.879  1 11.74  ? 202  LYS A NZ  1 
ATOM   1437 N  N   . GLN A 1 211 ? 4.288   -17.046 59.34   1 15.23  ? 203  GLN A N   1 
ATOM   1438 C  CA  . GLN A 1 211 ? 5.239   -18.088 59.74   1 12.942 ? 203  GLN A CA  1 
ATOM   1439 C  C   . GLN A 1 211 ? 5.708   -17.821 61.173  1 14.201 ? 203  GLN A C   1 
ATOM   1440 O  O   . GLN A 1 211 ? 6.521   -16.936 61.457  1 15.381 ? 203  GLN A O   1 
ATOM   1441 C  CB  . GLN A 1 211 ? 6.417   -18.023 58.79   1 16.236 ? 203  GLN A CB  1 
ATOM   1442 C  CG  . GLN A 1 211 ? 6.107   -18.8   57.515  1 17.211 ? 203  GLN A CG  1 
ATOM   1443 C  CD  . GLN A 1 211 ? 7.332   -18.968 56.63   1 22.022 ? 203  GLN A CD  1 
ATOM   1444 O  OE1 . GLN A 1 211 ? 7.965   -17.991 56.207  1 22.122 ? 203  GLN A OE1 1 
ATOM   1445 N  NE2 . GLN A 1 211 ? 7.726   -20.212 56.371  1 24.034 ? 203  GLN A NE2 1 
ATOM   1446 N  N   . CYS A 1 212 ? 5.113   -18.592 62.043  1 12.602 ? 204  CYS A N   1 
ATOM   1447 C  CA  . CYS A 1 212 ? 5.28    -18.563 63.488  1 13.212 ? 204  CYS A CA  1 
ATOM   1448 C  C   . CYS A 1 212 ? 6.767   -18.721 63.851  1 14.774 ? 204  CYS A C   1 
ATOM   1449 O  O   . CYS A 1 212 ? 7.363   -19.723 63.503  1 16.733 ? 204  CYS A O   1 
ATOM   1450 C  CB  . CYS A 1 212 ? 4.532   -19.797 64.015  1 11.405 ? 204  CYS A CB  1 
ATOM   1451 S  SG  . CYS A 1 212 ? 4.624   -19.851 65.862  1 17.353 ? 204  CYS A SG  1 
ATOM   1452 N  N   . SER A 1 213 ? 7.315   -17.783 64.641  1 18.276 ? 205  SER A N   1 
ATOM   1453 C  CA  . SER A 1 213 ? 8.726   -17.856 64.979  1 23.463 ? 205  SER A CA  1 
ATOM   1454 C  C   . SER A 1 213 ? 9.012   -18.896 66.063  1 26.057 ? 205  SER A C   1 
ATOM   1455 O  O   . SER A 1 213 ? 10.177  -19.176 66.282  1 26.215 ? 205  SER A O   1 
ATOM   1456 C  CB  . SER A 1 213 ? 9.276   -16.49  65.346  1 23.389 ? 205  SER A CB  1 
ATOM   1457 O  OG  . SER A 1 213 ? 8.722   -16.02  66.577  1 26.139 ? 205  SER A OG  1 
ATOM   1458 N  N   . VAL A 1 214 ? 7.964   -19.463 66.706  1 22.852 ? 206  VAL A N   1 
ATOM   1459 C  CA  . VAL A 1 214 ? 8.15    -20.392 67.815  1 23.81  ? 206  VAL A CA  1 
ATOM   1460 C  C   . VAL A 1 214 ? 8.112   -21.821 67.277  1 24.508 ? 206  VAL A C   1 
ATOM   1461 O  O   . VAL A 1 214 ? 9.077   -22.545 67.42   1 25.735 ? 206  VAL A O   1 
ATOM   1462 C  CB  . VAL A 1 214 ? 7.259   -20.103 69.05   1 23.495 ? 206  VAL A CB  1 
ATOM   1463 C  CG1 . VAL A 1 214 ? 7.397   -21.117 70.197  1 22.476 ? 206  VAL A CG1 1 
ATOM   1464 C  CG2 . VAL A 1 214 ? 7.44    -18.673 69.552  1 20.214 ? 206  VAL A CG2 1 
ATOM   1465 N  N   . THR A 1 215 ? 7.049   -22.174 66.548  1 20.611 ? 207  THR A N   1 
ATOM   1466 C  CA  . THR A 1 215 ? 6.782   -23.491 65.995  1 17.116 ? 207  THR A CA  1 
ATOM   1467 C  C   . THR A 1 215 ? 7.362   -23.617 64.587  1 19.239 ? 207  THR A C   1 
ATOM   1468 O  O   . THR A 1 215 ? 7.636   -24.731 64.155  1 19.099 ? 207  THR A O   1 
ATOM   1469 C  CB  . THR A 1 215 ? 5.271   -23.814 66.027  1 15.922 ? 207  THR A CB  1 
ATOM   1470 O  OG1 . THR A 1 215 ? 4.701   -23.013 65.002  1 17.262 ? 207  THR A OG1 1 
ATOM   1471 C  CG2 . THR A 1 215 ? 4.551   -23.423 67.306  1 15.476 ? 207  THR A CG2 1 
ATOM   1472 N  N   . GLY A 1 216 ? 7.544   -22.51  63.853  1 17.425 ? 208  GLY A N   1 
ATOM   1473 C  CA  . GLY A 1 216 ? 7.886   -22.65  62.426  1 19.085 ? 208  GLY A CA  1 
ATOM   1474 C  C   . GLY A 1 216 ? 6.688   -22.994 61.536  1 18.113 ? 208  GLY A C   1 
ATOM   1475 O  O   . GLY A 1 216 ? 6.844   -23.142 60.296  1 20.832 ? 208  GLY A O   1 
ATOM   1476 N  N   . ASN A 1 217 ? 5.471   -23.117 62.118  1 18.996 ? 209  ASN A N   1 
ATOM   1477 C  CA  . ASN A 1 217 ? 4.232   -23.377 61.374  1 18.947 ? 209  ASN A CA  1 
ATOM   1478 C  C   . ASN A 1 217 ? 3.856   -22.236 60.438  1 15.966 ? 209  ASN A C   1 
ATOM   1479 O  O   . ASN A 1 217 ? 3.937   -21.068 60.81   1 17.421 ? 209  ASN A O   1 
ATOM   1480 C  CB  . ASN A 1 217 ? 3.001   -23.69  62.236  1 19.621 ? 209  ASN A CB  1 
ATOM   1481 C  CG  . ASN A 1 217 ? 3.138   -24.962 63.031  1 21.28  ? 209  ASN A CG  1 
ATOM   1482 O  OD1 . ASN A 1 217 ? 4.139   -25.68  62.894  1 18.869 ? 209  ASN A OD1 1 
ATOM   1483 N  ND2 . ASN A 1 217 ? 2.198   -25.189 63.94   1 20.779 ? 209  ASN A ND2 1 
ATOM   1484 N  N   . LEU A 1 218 ? 3.512   -22.597 59.188  1 14.314 ? 210  LEU A N   1 
ATOM   1485 C  CA  . LEU A 1 218 ? 2.833   -21.656 58.306  1 11.973 ? 210  LEU A CA  1 
ATOM   1486 C  C   . LEU A 1 218 ? 1.38    -21.567 58.769  1 14.29  ? 210  LEU A C   1 
ATOM   1487 O  O   . LEU A 1 218 ? 0.618   -22.527 58.612  1 17.431 ? 210  LEU A O   1 
ATOM   1488 C  CB  . LEU A 1 218 ? 2.983   -22.169 56.845  1 11.044 ? 210  LEU A CB  1 
ATOM   1489 C  CG  . LEU A 1 218 ? 2.447   -21.25  55.755  1 12.771 ? 210  LEU A CG  1 
ATOM   1490 C  CD1 . LEU A 1 218 ? 3.134   -19.874 55.637  1 11.997 ? 210  LEU A CD1 1 
ATOM   1491 C  CD2 . LEU A 1 218 ? 2.556   -22.071 54.413  1 13.674 ? 210  LEU A CD2 1 
ATOM   1492 N  N   . VAL A 1 219 ? 0.98    -20.424 59.367  1 13.12  ? 211  VAL A N   1 
ATOM   1493 C  CA  . VAL A 1 219 ? -0.346  -20.38  59.966  1 15.465 ? 211  VAL A CA  1 
ATOM   1494 C  C   . VAL A 1 219 ? -1.22   -19.517 59.073  1 14.3   ? 211  VAL A C   1 
ATOM   1495 O  O   . VAL A 1 219 ? -0.813  -18.415 58.691  1 13.233 ? 211  VAL A O   1 
ATOM   1496 C  CB  . VAL A 1 219 ? -0.321  -19.805 61.394  1 16.099 ? 211  VAL A CB  1 
ATOM   1497 C  CG1 . VAL A 1 219 ? -1.723  -19.827 62.015  1 20.238 ? 211  VAL A CG1 1 
ATOM   1498 C  CG2 . VAL A 1 219 ? 0.696   -20.559 62.259  1 15.659 ? 211  VAL A CG2 1 
ATOM   1499 N  N   . GLY A 1 220 ? -2.413  -20.016 58.754  1 17.575 ? 212  GLY A N   1 
ATOM   1500 C  CA  . GLY A 1 220 ? -3.198  -19.276 57.764  1 15.047 ? 212  GLY A CA  1 
ATOM   1501 C  C   . GLY A 1 220 ? -4.629  -19.777 57.726  1 16.128 ? 212  GLY A C   1 
ATOM   1502 O  O   . GLY A 1 220 ? -5.081  -20.454 58.649  1 16.688 ? 212  GLY A O   1 
ATOM   1503 N  N   . PHE A 1 221 ? -5.306  -19.434 56.63   1 15.021 ? 213  PHE A N   1 
ATOM   1504 C  CA  . PHE A 1 221 ? -6.721  -19.678 56.51   1 12.125 ? 213  PHE A CA  1 
ATOM   1505 C  C   . PHE A 1 221 ? -7.011  -19.554 55.009  1 13.706 ? 213  PHE A C   1 
ATOM   1506 O  O   . PHE A 1 221 ? -6.164  -19.093 54.244  1 16.929 ? 213  PHE A O   1 
ATOM   1507 C  CB  . PHE A 1 221 ? -7.57   -18.682 57.294  1 11.99  ? 213  PHE A CB  1 
ATOM   1508 C  CG  . PHE A 1 221 ? -7.458  -17.231 56.877  1 12.416 ? 213  PHE A CG  1 
ATOM   1509 C  CD1 . PHE A 1 221 ? -6.282  -16.47  57.138  1 15.28  ? 213  PHE A CD1 1 
ATOM   1510 C  CD2 . PHE A 1 221 ? -8.485  -16.675 56.1    1 10.848 ? 213  PHE A CD2 1 
ATOM   1511 C  CE1 . PHE A 1 221 ? -6.203  -15.136 56.712  1 13.51  ? 213  PHE A CE1 1 
ATOM   1512 C  CE2 . PHE A 1 221 ? -8.446  -15.355 55.726  1 13.011 ? 213  PHE A CE2 1 
ATOM   1513 C  CZ  . PHE A 1 221 ? -7.265  -14.602 55.933  1 11.03  ? 213  PHE A CZ  1 
ATOM   1514 N  N   . GLY A 1 222 ? -8.227  -19.9   54.633  1 13.545 ? 214  GLY A N   1 
ATOM   1515 C  CA  . GLY A 1 222 ? -8.698  -19.5   53.308  1 12.911 ? 214  GLY A CA  1 
ATOM   1516 C  C   . GLY A 1 222 ? -10.18  -19.208 53.491  1 13.921 ? 214  GLY A C   1 
ATOM   1517 O  O   . GLY A 1 222 ? -10.841 -19.969 54.201  1 16.316 ? 214  GLY A O   1 
ATOM   1518 N  N   . TYR A 1 223 ? -10.691 -18.086 52.962  1 12.891 ? 215  TYR A N   1 
ATOM   1519 C  CA  . TYR A 1 223 ? -12.134 -17.801 53.037  1 12.523 ? 215  TYR A CA  1 
ATOM   1520 C  C   . TYR A 1 223 ? -12.74  -17.981 51.637  1 11.271 ? 215  TYR A C   1 
ATOM   1521 O  O   . TYR A 1 223 ? -11.983 -18.206 50.663  1 15.701 ? 215  TYR A O   1 
ATOM   1522 C  CB  . TYR A 1 223 ? -12.334 -16.417 53.69   1 13.786 ? 215  TYR A CB  1 
ATOM   1523 C  CG  . TYR A 1 223 ? -11.998 -15.285 52.728  1 12.603 ? 215  TYR A CG  1 
ATOM   1524 C  CD1 . TYR A 1 223 ? -10.687 -14.847 52.542  1 12.931 ? 215  TYR A CD1 1 
ATOM   1525 C  CD2 . TYR A 1 223 ? -12.992 -14.695 51.938  1 14.329 ? 215  TYR A CD2 1 
ATOM   1526 C  CE1 . TYR A 1 223 ? -10.395 -13.856 51.599  1 14.961 ? 215  TYR A CE1 1 
ATOM   1527 C  CE2 . TYR A 1 223 ? -12.714 -13.705 50.995  1 12.762 ? 215  TYR A CE2 1 
ATOM   1528 C  CZ  . TYR A 1 223 ? -11.411 -13.261 50.849  1 13.953 ? 215  TYR A CZ  1 
ATOM   1529 O  OH  . TYR A 1 223 ? -11.14  -12.301 49.906  1 14.429 ? 215  TYR A OH  1 
ATOM   1530 N  N   . GLU A 1 224 ? -14.104 -17.99  51.563  1 11.322 ? 216  GLU A N   1 
ATOM   1531 C  CA  . GLU A 1 224 ? -14.795 -18.529 50.392  1 12.225 ? 216  GLU A CA  1 
ATOM   1532 C  C   . GLU A 1 224 ? -14.272 -19.925 50.067  1 10.536 ? 216  GLU A C   1 
ATOM   1533 O  O   . GLU A 1 224 ? -14.046 -20.289 48.868  1 9.561  ? 216  GLU A O   1 
ATOM   1534 C  CB  . GLU A 1 224 ? -14.747 -17.645 49.133  1 10.558 ? 216  GLU A CB  1 
ATOM   1535 C  CG  . GLU A 1 224 ? -15.462 -16.301 49.411  1 12.595 ? 216  GLU A CG  1 
ATOM   1536 C  CD  . GLU A 1 224 ? -15.696 -15.376 48.262  1 12.491 ? 216  GLU A CD  1 
ATOM   1537 O  OE1 . GLU A 1 224 ? -16.098 -15.994 47.233  1 13.962 ? 216  GLU A OE1 1 
ATOM   1538 O  OE2 . GLU A 1 224 ? -15.65  -14.086 48.365  1 15.478 ? 216  GLU A OE2 1 
ATOM   1539 N  N   . ALA A 1 225 ? -14.139 -20.708 51.151  1 13.239 ? 217  ALA A N   1 
ATOM   1540 C  CA  . ALA A 1 225 ? -13.29  -21.905 51.133  1 12.855 ? 217  ALA A CA  1 
ATOM   1541 C  C   . ALA A 1 225 ? -13.994 -23.031 50.378  1 13.62  ? 217  ALA A C   1 
ATOM   1542 O  O   . ALA A 1 225 ? -13.349 -23.986 49.912  1 14.207 ? 217  ALA A O   1 
ATOM   1543 C  CB  . ALA A 1 225 ? -12.945 -22.293 52.537  1 13.237 ? 217  ALA A CB  1 
ATOM   1544 N  N   . LYS A 1 226 ? -15.315 -22.866 50.201  1 14.547 ? 218  LYS A N   1 
ATOM   1545 C  CA  . LYS A 1 226 ? -16.125 -23.879 49.55   1 13.299 ? 218  LYS A CA  1 
ATOM   1546 C  C   . LYS A 1 226 ? -16.607 -23.362 48.191  1 13.517 ? 218  LYS A C   1 
ATOM   1547 O  O   . LYS A 1 226 ? -17.389 -24.037 47.54   1 16.289 ? 218  LYS A O   1 
ATOM   1548 C  CB  . LYS A 1 226 ? -17.269 -24.379 50.423  1 13.668 ? 218  LYS A CB  1 
ATOM   1549 C  CG  . LYS A 1 226 ? -16.77  -25.126 51.667  1 18.335 ? 218  LYS A CG  1 
ATOM   1550 C  CD  . LYS A 1 226 ? -17.839 -25.97  52.39   1 16.506 ? 218  LYS A CD  1 
ATOM   1551 C  CE  . LYS A 1 226 ? -17.269 -26.576 53.712  1 20.233 ? 218  LYS A CE  1 
ATOM   1552 N  NZ  . LYS A 1 226 ? -17.98  -27.771 54.271  1 17.633 ? 218  LYS A NZ  1 
ATOM   1553 N  N   . GLY A 1 227 ? -16.137 -22.198 47.736  1 12.58  ? 219  GLY A N   1 
ATOM   1554 C  CA  . GLY A 1 227 ? -16.509 -21.69  46.394  1 14.403 ? 219  GLY A CA  1 
ATOM   1555 C  C   . GLY A 1 227 ? -17.076 -20.267 46.456  1 14.261 ? 219  GLY A C   1 
ATOM   1556 O  O   . GLY A 1 227 ? -17.145 -19.694 47.545  1 11.319 ? 219  GLY A O   1 
ATOM   1557 N  N   . LEU A 1 228 ? -17.423 -19.679 45.278  1 13.954 ? 220  LEU A N   1 
ATOM   1558 C  CA  . LEU A 1 228 ? -17.885 -18.287 45.181  1 14.184 ? 220  LEU A CA  1 
ATOM   1559 C  C   . LEU A 1 228 ? -18.991 -17.963 46.188  1 17.314 ? 220  LEU A C   1 
ATOM   1560 O  O   . LEU A 1 228 ? -20.041 -18.64  46.287  1 15.311 ? 220  LEU A O   1 
ATOM   1561 C  CB  . LEU A 1 228 ? -18.374 -18.265 43.729  1 17.901 ? 220  LEU A CB  1 
ATOM   1562 C  CG  . LEU A 1 228 ? -18.037 -17.133 42.779  1 19.01  ? 220  LEU A CG  1 
ATOM   1563 C  CD1 . LEU A 1 228 ? -16.584 -16.651 42.674  1 11.322 ? 220  LEU A CD1 1 
ATOM   1564 C  CD2 . LEU A 1 228 ? -18.574 -17.607 41.356  1 18.545 ? 220  LEU A CD2 1 
ATOM   1565 N  N   . ALA A 1 229 ? -18.706 -16.927 46.993  1 16.843 ? 221  ALA A N   1 
ATOM   1566 C  CA  . ALA A 1 229 ? -19.657 -16.277 47.88   1 18.754 ? 221  ALA A CA  1 
ATOM   1567 C  C   . ALA A 1 229 ? -20.002 -17.155 49.085  1 18.721 ? 221  ALA A C   1 
ATOM   1568 O  O   . ALA A 1 229 ? -20.883 -16.767 49.858  1 16.191 ? 221  ALA A O   1 
ATOM   1569 C  CB  . ALA A 1 229 ? -20.936 -15.791 47.147  1 19.159 ? 221  ALA A CB  1 
ATOM   1570 N  N   . THR A 1 230 ? -19.24  -18.236 49.314  1 15.12  ? 222  THR A N   1 
ATOM   1571 C  CA  . THR A 1 230 ? -19.404 -19.022 50.544  1 12.559 ? 222  THR A CA  1 
ATOM   1572 C  C   . THR A 1 230 ? -18.835 -18.296 51.767  1 16.038 ? 222  THR A C   1 
ATOM   1573 O  O   . THR A 1 230 ? -17.791 -17.618 51.733  1 14.772 ? 222  THR A O   1 
ATOM   1574 C  CB  . THR A 1 230 ? -18.85  -20.447 50.398  1 15.05  ? 222  THR A CB  1 
ATOM   1575 O  OG1 . THR A 1 230 ? -17.431 -20.445 50.141  1 12.244 ? 222  THR A OG1 1 
ATOM   1576 C  CG2 . THR A 1 230 ? -19.579 -21.256 49.334  1 15.035 ? 222  THR A CG2 1 
ATOM   1577 N  N   . LYS A 1 231 ? -19.511 -18.533 52.9    1 13.636 ? 223  LYS A N   1 
ATOM   1578 C  CA  . LYS A 1 231 ? -19.084 -18.017 54.189  1 18.42  ? 223  LYS A CA  1 
ATOM   1579 C  C   . LYS A 1 231 ? -18.016 -18.865 54.849  1 17.716 ? 223  LYS A C   1 
ATOM   1580 O  O   . LYS A 1 231 ? -17.423 -18.447 55.858  1 14.516 ? 223  LYS A O   1 
ATOM   1581 C  CB  . LYS A 1 231 ? -20.328 -17.835 55.066  1 19.102 ? 223  LYS A CB  1 
ATOM   1582 C  CG  . LYS A 1 231 ? -21.285 -16.727 54.673  1 22.096 ? 223  LYS A CG  1 
ATOM   1583 C  CD  . LYS A 1 231 ? -22.395 -16.444 55.714  1 26.525 ? 223  LYS A CD  1 
ATOM   1584 C  CE  . LYS A 1 231 ? -23.522 -17.426 55.796  1 36.645 ? 223  LYS A CE  1 
ATOM   1585 N  NZ  . LYS A 1 231 ? -24.314 -17.031 56.974  1 47.12  ? 223  LYS A NZ  1 
ATOM   1586 N  N   . ASP A 1 232 ? -17.794 -20.095 54.334  1 19.113 ? 224  ASP A N   1 
ATOM   1587 C  CA  . ASP A 1 232 ? -16.823 -21.008 54.931  1 17.372 ? 224  ASP A CA  1 
ATOM   1588 C  C   . ASP A 1 232 ? -15.4   -20.44  54.972  1 14.146 ? 224  ASP A C   1 
ATOM   1589 O  O   . ASP A 1 232 ? -14.902 -19.872 53.989  1 13.852 ? 224  ASP A O   1 
ATOM   1590 C  CB  . ASP A 1 232 ? -16.831 -22.331 54.197  1 15.686 ? 224  ASP A CB  1 
ATOM   1591 C  CG  . ASP A 1 232 ? -18.254 -22.889 54.118  1 17.414 ? 224  ASP A CG  1 
ATOM   1592 O  OD1 . ASP A 1 232 ? -18.728 -23.536 55.11   1 20.193 ? 224  ASP A OD1 1 
ATOM   1593 O  OD2 . ASP A 1 232 ? -18.912 -22.624 53.119  1 18.838 ? 224  ASP A OD2 1 
ATOM   1594 N  N   . VAL A 1 233 ? -14.811 -20.537 56.18   1 12.076 ? 225  VAL A N   1 
ATOM   1595 C  CA  . VAL A 1 233 ? -13.365 -20.35  56.343  1 12.728 ? 225  VAL A CA  1 
ATOM   1596 C  C   . VAL A 1 233 ? -12.748 -21.661 56.799  1 14.971 ? 225  VAL A C   1 
ATOM   1597 O  O   . VAL A 1 233 ? -13.209 -22.259 57.786  1 17.365 ? 225  VAL A O   1 
ATOM   1598 C  CB  . VAL A 1 233 ? -13.082 -19.195 57.325  1 13.249 ? 225  VAL A CB  1 
ATOM   1599 C  CG1 . VAL A 1 233 ? -11.564 -18.953 57.531  1 14.87  ? 225  VAL A CG1 1 
ATOM   1600 C  CG2 . VAL A 1 233 ? -13.901 -18.012 56.801  1 12.303 ? 225  VAL A CG2 1 
ATOM   1601 N  N   . TYR A 1 234 ? -11.599 -21.968 56.193  1 14.652 ? 226  TYR A N   1 
ATOM   1602 C  CA  . TYR A 1 234 ? -10.725 -23.049 56.653  1 15.096 ? 226  TYR A CA  1 
ATOM   1603 C  C   . TYR A 1 234 ? -9.424  -22.496 57.272  1 16.532 ? 226  TYR A C   1 
ATOM   1604 O  O   . TYR A 1 234 ? -8.669  -21.832 56.592  1 14.539 ? 226  TYR A O   1 
ATOM   1605 C  CB  . TYR A 1 234 ? -10.428 -23.916 55.415  1 11.379 ? 226  TYR A CB  1 
ATOM   1606 C  CG  . TYR A 1 234 ? -9.435  -25.039 55.729  1 13.705 ? 226  TYR A CG  1 
ATOM   1607 C  CD1 . TYR A 1 234 ? -9.817  -26.129 56.526  1 15.12  ? 226  TYR A CD1 1 
ATOM   1608 C  CD2 . TYR A 1 234 ? -8.146  -25.043 55.169  1 13.362 ? 226  TYR A CD2 1 
ATOM   1609 C  CE1 . TYR A 1 234 ? -8.939  -27.187 56.779  1 15.788 ? 226  TYR A CE1 1 
ATOM   1610 C  CE2 . TYR A 1 234 ? -7.258  -26.103 55.4    1 13.994 ? 226  TYR A CE2 1 
ATOM   1611 C  CZ  . TYR A 1 234 ? -7.637  -27.14  56.261  1 17.119 ? 226  TYR A CZ  1 
ATOM   1612 O  OH  . TYR A 1 234 ? -6.793  -28.204 56.462  1 21.314 ? 226  TYR A OH  1 
ATOM   1613 N  N   . TYR A 1 235 ? -9.186  -22.736 58.59   1 14.089 ? 227  TYR A N   1 
ATOM   1614 C  CA  . TYR A 1 235 ? -7.964  -22.43  59.297  1 13.375 ? 227  TYR A CA  1 
ATOM   1615 C  C   . TYR A 1 235 ? -7.004  -23.62  59.262  1 11.953 ? 227  TYR A C   1 
ATOM   1616 O  O   . TYR A 1 235 ? -7.406  -24.778 59.363  1 12.012 ? 227  TYR A O   1 
ATOM   1617 C  CB  . TYR A 1 235 ? -8.385  -22.058 60.745  1 12.45  ? 227  TYR A CB  1 
ATOM   1618 C  CG  . TYR A 1 235 ? -7.31   -22.376 61.785  1 15.769 ? 227  TYR A CG  1 
ATOM   1619 C  CD1 . TYR A 1 235 ? -6.166  -21.539 61.936  1 17.062 ? 227  TYR A CD1 1 
ATOM   1620 C  CD2 . TYR A 1 235 ? -7.439  -23.504 62.642  1 18.136 ? 227  TYR A CD2 1 
ATOM   1621 C  CE1 . TYR A 1 235 ? -5.213  -21.8   62.93   1 16.771 ? 227  TYR A CE1 1 
ATOM   1622 C  CE2 . TYR A 1 235 ? -6.469  -23.757 63.623  1 18.9   ? 227  TYR A CE2 1 
ATOM   1623 C  CZ  . TYR A 1 235 ? -5.34   -22.94  63.736  1 17.685 ? 227  TYR A CZ  1 
ATOM   1624 O  OH  . TYR A 1 235 ? -4.456  -23.271 64.757  1 18.933 ? 227  TYR A OH  1 
ATOM   1625 N  N   . PHE A 1 236 ? -5.695  -23.336 59.168  1 10.748 ? 228  PHE A N   1 
ATOM   1626 C  CA  . PHE A 1 236 ? -4.707  -24.404 59.046  1 11.965 ? 228  PHE A CA  1 
ATOM   1627 C  C   . PHE A 1 236 ? -3.402  -23.912 59.69   1 14.42  ? 228  PHE A C   1 
ATOM   1628 O  O   . PHE A 1 236 ? -3.146  -22.706 59.79   1 14.264 ? 228  PHE A O   1 
ATOM   1629 C  CB  . PHE A 1 236 ? -4.596  -24.926 57.596  1 12.293 ? 228  PHE A CB  1 
ATOM   1630 C  CG  . PHE A 1 236 ? -4.035  -23.826 56.696  1 13.577 ? 228  PHE A CG  1 
ATOM   1631 C  CD1 . PHE A 1 236 ? -2.669  -23.546 56.709  1 13.709 ? 228  PHE A CD1 1 
ATOM   1632 C  CD2 . PHE A 1 236 ? -4.852  -23.031 55.906  1 14.722 ? 228  PHE A CD2 1 
ATOM   1633 C  CE1 . PHE A 1 236 ? -2.141  -22.522 55.965  1 13.807 ? 228  PHE A CE1 1 
ATOM   1634 C  CE2 . PHE A 1 236 ? -4.306  -22.052 55.084  1 13.79  ? 228  PHE A CE2 1 
ATOM   1635 C  CZ  . PHE A 1 236 ? -2.95   -21.767 55.154  1 16.157 ? 228  PHE A CZ  1 
ATOM   1636 N  N   . GLU A 1 237 ? -2.596  -24.868 60.15   1 14.154 ? 229  GLU A N   1 
ATOM   1637 C  CA  . GLU A 1 237 ? -1.182  -24.703 60.438  1 13.979 ? 229  GLU A CA  1 
ATOM   1638 C  C   . GLU A 1 237 ? -0.423  -25.832 59.756  1 16.089 ? 229  GLU A C   1 
ATOM   1639 O  O   . GLU A 1 237 ? -0.74   -27.013 59.926  1 15.446 ? 229  GLU A O   1 
ATOM   1640 C  CB  . GLU A 1 237 ? -0.886  -24.636 61.953  1 15.416 ? 229  GLU A CB  1 
ATOM   1641 C  CG  . GLU A 1 237 ? -1.667  -23.521 62.64   1 15.522 ? 229  GLU A CG  1 
ATOM   1642 C  CD  . GLU A 1 237 ? -1.198  -23.105 64.017  1 15.384 ? 229  GLU A CD  1 
ATOM   1643 O  OE1 . GLU A 1 237 ? -0.029  -23.391 64.309  1 15.799 ? 229  GLU A OE1 1 
ATOM   1644 O  OE2 . GLU A 1 237 ? -1.935  -22.442 64.777  1 17.4   ? 229  GLU A OE2 1 
ATOM   1645 N  N   . VAL A 1 238 ? 0.545   -25.452 58.9    1 17.732 ? 230  VAL A N   1 
ATOM   1646 C  CA  . VAL A 1 238 ? 1.405   -26.362 58.167  1 17.781 ? 230  VAL A CA  1 
ATOM   1647 C  C   . VAL A 1 238 ? 2.73    -26.364 58.908  1 15.843 ? 230  VAL A C   1 
ATOM   1648 O  O   . VAL A 1 238 ? 3.339   -25.314 58.996  1 16.732 ? 230  VAL A O   1 
ATOM   1649 C  CB  . VAL A 1 238 ? 1.605   -25.976 56.696  1 17.294 ? 230  VAL A CB  1 
ATOM   1650 C  CG1 . VAL A 1 238 ? 2.568   -26.948 56.009  1 14.247 ? 230  VAL A CG1 1 
ATOM   1651 C  CG2 . VAL A 1 238 ? 0.277   -25.878 55.923  1 15.901 ? 230  VAL A CG2 1 
ATOM   1652 N  N   . ASP A 1 239 ? 3.204   -27.535 59.376  1 21.219 ? 231  ASP A N   1 
ATOM   1653 C  CA  . ASP A 1 239 ? 4.461   -27.607 60.125  1 23.326 ? 231  ASP A CA  1 
ATOM   1654 C  C   . ASP A 1 239 ? 5.674   -27.448 59.213  1 22.889 ? 231  ASP A C   1 
ATOM   1655 O  O   . ASP A 1 239 ? 5.484   -27.445 57.99   1 21.365 ? 231  ASP A O   1 
ATOM   1656 C  CB  . ASP A 1 239 ? 4.464   -28.827 61.035  1 24.491 ? 231  ASP A CB  1 
ATOM   1657 C  CG  . ASP A 1 239 ? 4.818   -30.156 60.402  1 23.47  ? 231  ASP A CG  1 
ATOM   1658 O  OD1 . ASP A 1 239 ? 5.078   -30.255 59.183  1 25.423 ? 231  ASP A OD1 1 
ATOM   1659 O  OD2 . ASP A 1 239 ? 4.887   -31.089 61.184  1 26.333 ? 231  ASP A OD2 1 
ATOM   1660 N  N   . PRO A 1 240 ? 6.93    -27.304 59.736  1 19.939 ? 232  PRO A N   1 
ATOM   1661 C  CA  . PRO A 1 240 ? 8.1     -27.11  58.866  1 23.68  ? 232  PRO A CA  1 
ATOM   1662 C  C   . PRO A 1 240 ? 8.419   -28.282 57.914  1 22.934 ? 232  PRO A C   1 
ATOM   1663 O  O   . PRO A 1 240 ? 9.261   -28.185 57.029  1 18.201 ? 232  PRO A O   1 
ATOM   1664 C  CB  . PRO A 1 240 ? 9.209   -26.918 59.887  1 21.885 ? 232  PRO A CB  1 
ATOM   1665 C  CG  . PRO A 1 240 ? 8.538   -26.355 61.142  1 20.8   ? 232  PRO A CG  1 
ATOM   1666 C  CD  . PRO A 1 240 ? 7.296   -27.201 61.196  1 19.975 ? 232  PRO A CD  1 
ATOM   1667 N  N   . SER A 1 241 ? 7.711   -29.41  58.079  1 18.886 ? 233  SER A N   1 
ATOM   1668 C  CA  . SER A 1 241 ? 7.894   -30.569 57.244  1 19.471 ? 233  SER A CA  1 
ATOM   1669 C  C   . SER A 1 241 ? 6.872   -30.559 56.105  1 19.578 ? 233  SER A C   1 
ATOM   1670 O  O   . SER A 1 241 ? 6.861   -31.469 55.301  1 25.288 ? 233  SER A O   1 
ATOM   1671 C  CB  . SER A 1 241 ? 7.851   -31.829 58.144  1 23.39  ? 233  SER A CB  1 
ATOM   1672 O  OG  . SER A 1 241 ? 6.544   -32.342 58.288  1 32.078 ? 233  SER A OG  1 
ATOM   1673 N  N   . GLY A 1 242 ? 5.899   -29.627 56.132  1 23.165 ? 234  GLY A N   1 
ATOM   1674 C  CA  . GLY A 1 242 ? 4.888   -29.519 55.082  1 21.067 ? 234  GLY A CA  1 
ATOM   1675 C  C   . GLY A 1 242 ? 3.566   -30.255 55.368  1 25.061 ? 234  GLY A C   1 
ATOM   1676 O  O   . GLY A 1 242 ? 2.733   -30.387 54.463  1 22.518 ? 234  GLY A O   1 
ATOM   1677 N  N   . LYS A 1 243 ? 3.311   -30.653 56.632  1 23.373 ? 235  LYS A N   1 
ATOM   1678 C  CA  . LYS A 1 243 ? 2.105   -31.389 56.999  1 22.777 ? 235  LYS A CA  1 
ATOM   1679 C  C   . LYS A 1 243 ? 1.117   -30.464 57.712  1 18.164 ? 235  LYS A C   1 
ATOM   1680 O  O   . LYS A 1 243 ? 1.504   -29.684 58.57   1 17.968 ? 235  LYS A O   1 
ATOM   1681 C  CB  . LYS A 1 243 ? 2.554   -32.502 57.958  1 27.044 ? 235  LYS A CB  1 
ATOM   1682 C  CG  . LYS A 1 243 ? 1.523   -33.643 58.108  1 29.147 ? 235  LYS A CG  1 
ATOM   1683 C  CD  . LYS A 1 243 ? 1.887   -34.674 59.177  1 35.07  ? 235  LYS A CD  1 
ATOM   1684 C  CE  . LYS A 1 243 ? 1.617   -34.184 60.574  1 41.316 ? 235  LYS A CE  1 
ATOM   1685 N  NZ  . LYS A 1 243 ? 2.025   -35.009 61.718  1 45.397 ? 235  LYS A NZ  1 
ATOM   1686 N  N   . VAL A 1 244 ? -0.177  -30.641 57.44   1 20.568 ? 236  VAL A N   1 
ATOM   1687 C  CA  . VAL A 1 244 ? -1.175  -29.884 58.172  1 17.136 ? 236  VAL A CA  1 
ATOM   1688 C  C   . VAL A 1 244 ? -1.287  -30.598 59.523  1 21.313 ? 236  VAL A C   1 
ATOM   1689 O  O   . VAL A 1 244 ? -1.644  -31.793 59.585  1 20.518 ? 236  VAL A O   1 
ATOM   1690 C  CB  . VAL A 1 244 ? -2.512  -29.87  57.417  1 17.52  ? 236  VAL A CB  1 
ATOM   1691 C  CG1 . VAL A 1 244 ? -3.632  -29.247 58.211  1 16.359 ? 236  VAL A CG1 1 
ATOM   1692 C  CG2 . VAL A 1 244 ? -2.383  -29.322 55.983  1 21.768 ? 236  VAL A CG2 1 
ATOM   1693 N  N   . VAL A 1 245 ? -0.918  -29.863 60.558  1 18.987 ? 237  VAL A N   1 
ATOM   1694 C  CA  . VAL A 1 245 ? -0.883  -30.353 61.93   1 20.081 ? 237  VAL A CA  1 
ATOM   1695 C  C   . VAL A 1 245 ? -2.08   -29.876 62.746  1 22.634 ? 237  VAL A C   1 
ATOM   1696 O  O   . VAL A 1 245 ? -2.362  -30.436 63.845  1 18.594 ? 237  VAL A O   1 
ATOM   1697 C  CB  . VAL A 1 245 ? 0.451   -30.127 62.674  1 20.194 ? 237  VAL A CB  1 
ATOM   1698 C  CG1 . VAL A 1 245 ? 1.54    -31.005 62.075  1 19.897 ? 237  VAL A CG1 1 
ATOM   1699 C  CG2 . VAL A 1 245 ? 0.946   -28.674 62.742  1 21.07  ? 237  VAL A CG2 1 
ATOM   1700 N  N   . ARG A 1 246 ? -2.737  -28.814 62.261  1 16.204 ? 238  ARG A N   1 
ATOM   1701 C  CA  . ARG A 1 246 ? -3.889  -28.207 62.934  1 18.346 ? 238  ARG A CA  1 
ATOM   1702 C  C   . ARG A 1 246 ? -4.783  -27.696 61.824  1 19.257 ? 238  ARG A C   1 
ATOM   1703 O  O   . ARG A 1 246 ? -4.269  -27.152 60.834  1 17.959 ? 238  ARG A O   1 
ATOM   1704 C  CB  . ARG A 1 246 ? -3.554  -26.995 63.81   1 22.015 ? 238  ARG A CB  1 
ATOM   1705 C  CG  . ARG A 1 246 ? -2.693  -27.304 65.035  1 24.325 ? 238  ARG A CG  1 
ATOM   1706 C  CD  . ARG A 1 246 ? -2.047  -26.077 65.644  1 19.58  ? 238  ARG A CD  1 
ATOM   1707 N  NE  . ARG A 1 246 ? -1.697  -26.11  67.067  1 23.251 ? 238  ARG A NE  1 
ATOM   1708 C  CZ  . ARG A 1 246 ? -1.069  -25.164 67.761  1 21.318 ? 238  ARG A CZ  1 
ATOM   1709 N  NH1 . ARG A 1 246 ? -0.49   -24.115 67.178  1 18.519 ? 238  ARG A NH1 1 
ATOM   1710 N  NH2 . ARG A 1 246 ? -1.004  -25.258 69.094  1 27.08  ? 238  ARG A NH2 1 
ATOM   1711 N  N   . ASP A 1 247 ? -6.087  -27.907 61.972  1 16.89  ? 239  ASP A N   1 
ATOM   1712 C  CA  . ASP A 1 247 ? -7.043  -27.244 61.092  1 17.15  ? 239  ASP A CA  1 
ATOM   1713 C  C   . ASP A 1 247 ? -8.398  -27.153 61.793  1 20.943 ? 239  ASP A C   1 
ATOM   1714 O  O   . ASP A 1 247 ? -8.605  -27.717 62.881  1 18.713 ? 239  ASP A O   1 
ATOM   1715 C  CB  . ASP A 1 247 ? -7.046  -27.862 59.683  1 15.877 ? 239  ASP A CB  1 
ATOM   1716 C  CG  . ASP A 1 247 ? -7.691  -29.243 59.543  1 21.035 ? 239  ASP A CG  1 
ATOM   1717 O  OD1 . ASP A 1 247 ? -8.145  -29.775 60.566  1 18.529 ? 239  ASP A OD1 1 
ATOM   1718 O  OD2 . ASP A 1 247 ? -7.751  -29.785 58.402  1 18.157 ? 239  ASP A OD2 1 
ATOM   1719 N  N   . LEU A 1 248 ? -9.322  -26.412 61.16   1 16.966 ? 240  LEU A N   1 
ATOM   1720 C  CA  . LEU A 1 248 ? -10.665 -26.165 61.65   1 15.753 ? 240  LEU A CA  1 
ATOM   1721 C  C   . LEU A 1 248 ? -11.449 -25.557 60.495  1 17.931 ? 240  LEU A C   1 
ATOM   1722 O  O   . LEU A 1 248 ? -10.98  -24.603 59.871  1 16.578 ? 240  LEU A O   1 
ATOM   1723 C  CB  . LEU A 1 248 ? -10.702 -25.227 62.865  1 19.69  ? 240  LEU A CB  1 
ATOM   1724 C  CG  . LEU A 1 248 ? -12.067 -25.05  63.535  1 19.461 ? 240  LEU A CG  1 
ATOM   1725 C  CD1 . LEU A 1 248 ? -12.401 -26.368 64.242  1 19.473 ? 240  LEU A CD1 1 
ATOM   1726 C  CD2 . LEU A 1 248 ? -12.048 -23.908 64.556  1 19.633 ? 240  LEU A CD2 1 
ATOM   1727 N  N   . TRP A 1 249 ? -12.686 -26.038 60.343  1 15.491 ? 241  TRP A N   1 
ATOM   1728 C  CA  . TRP A 1 249 ? -13.66  -25.355 59.501  1 17.802 ? 241  TRP A CA  1 
ATOM   1729 C  C   . TRP A 1 249 ? -14.597 -24.536 60.375  1 20.516 ? 241  TRP A C   1 
ATOM   1730 O  O   . TRP A 1 249 ? -14.932 -24.919 61.505  1 16.811 ? 241  TRP A O   1 
ATOM   1731 C  CB  . TRP A 1 249 ? -14.458 -26.385 58.727  1 16.253 ? 241  TRP A CB  1 
ATOM   1732 C  CG  . TRP A 1 249 ? -13.702 -26.967 57.582  1 17.658 ? 241  TRP A CG  1 
ATOM   1733 C  CD1 . TRP A 1 249 ? -12.937 -28.094 57.625  1 14.655 ? 241  TRP A CD1 1 
ATOM   1734 C  CD2 . TRP A 1 249 ? -13.687 -26.497 56.207  1 17.769 ? 241  TRP A CD2 1 
ATOM   1735 N  NE1 . TRP A 1 249 ? -12.528 -28.382 56.355  1 14.836 ? 241  TRP A NE1 1 
ATOM   1736 C  CE2 . TRP A 1 249 ? -12.879 -27.417 55.488  1 15.245 ? 241  TRP A CE2 1 
ATOM   1737 C  CE3 . TRP A 1 249 ? -14.208 -25.376 55.545  1 20.761 ? 241  TRP A CE3 1 
ATOM   1738 C  CZ2 . TRP A 1 249 ? -12.608 -27.298 54.125  1 16.173 ? 241  TRP A CZ2 1 
ATOM   1739 C  CZ3 . TRP A 1 249 ? -13.976 -25.297 54.176  1 23.225 ? 241  TRP A CZ3 1 
ATOM   1740 C  CH2 . TRP A 1 249 ? -13.189 -26.23  53.494  1 20.651 ? 241  TRP A CH2 1 
ATOM   1741 N  N   . LEU A 1 250 ? -14.916 -23.341 59.885  1 18.068 ? 242  LEU A N   1 
ATOM   1742 C  CA  . LEU A 1 250 ? -15.764 -22.358 60.561  1 16.69  ? 242  LEU A CA  1 
ATOM   1743 C  C   . LEU A 1 250 ? -16.39  -21.478 59.471  1 17.14  ? 242  LEU A C   1 
ATOM   1744 O  O   . LEU A 1 250 ? -16.302 -21.786 58.291  1 15.375 ? 242  LEU A O   1 
ATOM   1745 C  CB  . LEU A 1 250 ? -14.905 -21.53  61.535  1 18.456 ? 242  LEU A CB  1 
ATOM   1746 C  CG  . LEU A 1 250 ? -13.712 -20.768 60.91   1 18.614 ? 242  LEU A CG  1 
ATOM   1747 C  CD1 . LEU A 1 250 ? -13.69  -19.273 61.415  1 22.233 ? 242  LEU A CD1 1 
ATOM   1748 C  CD2 . LEU A 1 250 ? -12.388 -21.508 61.145  1 20.477 ? 242  LEU A CD2 1 
ATOM   1749 N  N   . GLU A 1 251 ? -17.091 -20.407 59.885  1 17.433 ? 243  GLU A N   1 
ATOM   1750 C  CA  . GLU A 1 251 ? -17.728 -19.455 58.989  1 16.908 ? 243  GLU A CA  1 
ATOM   1751 C  C   . GLU A 1 251 ? -17.517 -18.05  59.508  1 18.189 ? 243  GLU A C   1 
ATOM   1752 O  O   . GLU A 1 251 ? -17.357 -17.818 60.711  1 18.994 ? 243  GLU A O   1 
ATOM   1753 C  CB  . GLU A 1 251 ? -19.244 -19.684 58.897  1 19.259 ? 243  GLU A CB  1 
ATOM   1754 C  CG  . GLU A 1 251 ? -19.631 -21.051 58.342  1 18.309 ? 243  GLU A CG  1 
ATOM   1755 C  CD  . GLU A 1 251 ? -21.162 -21.156 58.316  1 26.471 ? 243  GLU A CD  1 
ATOM   1756 O  OE1 . GLU A 1 251 ? -21.745 -21.325 59.411  1 28.276 ? 243  GLU A OE1 1 
ATOM   1757 O  OE2 . GLU A 1 251 ? -21.739 -20.921 57.244  1 29.833 ? 243  GLU A OE2 1 
ATOM   1758 N  N   . ALA A 1 252 ? -17.476 -17.148 58.54   1 17.613 ? 244  ALA A N   1 
ATOM   1759 C  CA  . ALA A 1 252 ? -17.501 -15.74  58.822  1 19.36  ? 244  ALA A CA  1 
ATOM   1760 C  C   . ALA A 1 252 ? -18.958 -15.29  58.983  1 16.648 ? 244  ALA A C   1 
ATOM   1761 O  O   . ALA A 1 252 ? -19.87  -15.948 58.443  1 14.224 ? 244  ALA A O   1 
ATOM   1762 C  CB  . ALA A 1 252 ? -16.729 -14.987 57.719  1 17.456 ? 244  ALA A CB  1 
ATOM   1763 N  N   . PRO A 1 253 ? -19.24  -14.206 59.759  1 17.251 ? 245  PRO A N   1 
ATOM   1764 C  CA  . PRO A 1 253 ? -20.629 -13.758 59.973  1 16.016 ? 245  PRO A CA  1 
ATOM   1765 C  C   . PRO A 1 253 ? -21.306 -13.29  58.678  1 17.1   ? 245  PRO A C   1 
ATOM   1766 O  O   . PRO A 1 253 ? -22.538 -13.348 58.552  1 18.336 ? 245  PRO A O   1 
ATOM   1767 C  CB  . PRO A 1 253 ? -20.493 -12.556 60.904  1 17.373 ? 245  PRO A CB  1 
ATOM   1768 C  CG  . PRO A 1 253 ? -19.018 -12.137 60.743  1 15.767 ? 245  PRO A CG  1 
ATOM   1769 C  CD  . PRO A 1 253 ? -18.264 -13.375 60.49   1 16.735 ? 245  PRO A CD  1 
ATOM   1770 N  N   . TRP A 1 254 ? -20.508 -12.763 57.745  1 15.685 ? 246  TRP A N   1 
ATOM   1771 C  CA  . TRP A 1 254 ? -20.986 -12.563 56.357  1 12.588 ? 246  TRP A CA  1 
ATOM   1772 C  C   . TRP A 1 254 ? -19.904 -13.015 55.409  1 12.647 ? 246  TRP A C   1 
ATOM   1773 O  O   . TRP A 1 254 ? -18.774 -13.195 55.879  1 14.838 ? 246  TRP A O   1 
ATOM   1774 C  CB  . TRP A 1 254 ? -21.434 -11.117 56.046  1 12.561 ? 246  TRP A CB  1 
ATOM   1775 C  CG  . TRP A 1 254 ? -20.379 -10.034 55.861  1 14.5   ? 246  TRP A CG  1 
ATOM   1776 C  CD1 . TRP A 1 254 ? -19.801 -9.546  54.717  1 12.655 ? 246  TRP A CD1 1 
ATOM   1777 C  CD2 . TRP A 1 254 ? -19.771 -9.32   56.948  1 14.207 ? 246  TRP A CD2 1 
ATOM   1778 N  NE1 . TRP A 1 254 ? -18.888 -8.567  55.024  1 12.216 ? 246  TRP A NE1 1 
ATOM   1779 C  CE2 . TRP A 1 254 ? -18.861 -8.393  56.386  1 13.452 ? 246  TRP A CE2 1 
ATOM   1780 C  CE3 . TRP A 1 254 ? -19.951 -9.366  58.341  1 14.016 ? 246  TRP A CE3 1 
ATOM   1781 C  CZ2 . TRP A 1 254 ? -18.073 -7.562  57.183  1 13.439 ? 246  TRP A CZ2 1 
ATOM   1782 C  CZ3 . TRP A 1 254 ? -19.182 -8.539  59.131  1 13.593 ? 246  TRP A CZ3 1 
ATOM   1783 C  CH2 . TRP A 1 254 ? -18.236 -7.644  58.567  1 14.108 ? 246  TRP A CH2 1 
ATOM   1784 N  N   . CYS A 1 255 ? -20.233 -13.152 54.086  1 13.499 ? 247  CYS A N   1 
ATOM   1785 C  CA  . CYS A 1 255 ? -19.139 -13.414 53.158  1 13.824 ? 247  CYS A CA  1 
ATOM   1786 C  C   . CYS A 1 255 ? -18.379 -12.103 52.942  1 12.954 ? 247  CYS A C   1 
ATOM   1787 O  O   . CYS A 1 255 ? -18.781 -11.3   52.058  1 15.869 ? 247  CYS A O   1 
ATOM   1788 C  CB  . CYS A 1 255 ? -19.612 -13.924 51.786  1 15.972 ? 247  CYS A CB  1 
ATOM   1789 S  SG  . CYS A 1 255 ? -18.166 -14.424 50.781  1 15.428 ? 247  CYS A SG  1 
ATOM   1790 N  N   . ALA A 1 256 ? -17.257 -11.993 53.683  1 11.278 ? 248  ALA A N   1 
ATOM   1791 C  CA  . ALA A 1 256 ? -16.448 -10.79  53.884  1 13.43  ? 248  ALA A CA  1 
ATOM   1792 C  C   . ALA A 1 256 ? -15.129 -10.915 53.134  1 12.007 ? 248  ALA A C   1 
ATOM   1793 O  O   . ALA A 1 256 ? -14.626 -12.029 52.971  1 12.98  ? 248  ALA A O   1 
ATOM   1794 C  CB  . ALA A 1 256 ? -16.232 -10.662 55.412  1 14.472 ? 248  ALA A CB  1 
ATOM   1795 N  N   . PHE A 1 257 ? -14.498 -9.773  52.797  1 16.885 ? 249  PHE A N   1 
ATOM   1796 C  CA  . PHE A 1 257 ? -13.178 -9.761  52.19   1 14.792 ? 249  PHE A CA  1 
ATOM   1797 C  C   . PHE A 1 257 ? -12.206 -9.808  53.37   1 12.838 ? 249  PHE A C   1 
ATOM   1798 O  O   . PHE A 1 257 ? -11.889 -8.75   53.922  1 14.084 ? 249  PHE A O   1 
ATOM   1799 C  CB  . PHE A 1 257 ? -13.155 -8.453  51.392  1 15.202 ? 249  PHE A CB  1 
ATOM   1800 C  CG  . PHE A 1 257 ? -12.113 -8.2    50.335  1 13.501 ? 249  PHE A CG  1 
ATOM   1801 C  CD1 . PHE A 1 257 ? -10.857 -8.856  50.346  1 16.427 ? 249  PHE A CD1 1 
ATOM   1802 C  CD2 . PHE A 1 257 ? -12.391 -7.323  49.284  1 13.501 ? 249  PHE A CD2 1 
ATOM   1803 C  CE1 . PHE A 1 257 ? -9.89   -8.608  49.371  1 14.879 ? 249  PHE A CE1 1 
ATOM   1804 C  CE2 . PHE A 1 257 ? -11.43  -7.08   48.27   1 12.775 ? 249  PHE A CE2 1 
ATOM   1805 C  CZ  . PHE A 1 257 ? -10.175 -7.741  48.286  1 12.243 ? 249  PHE A CZ  1 
ATOM   1806 N  N   . ILE A 1 258 ? -11.666 -11.012 53.612  1 10.062 ? 250  ILE A N   1 
ATOM   1807 C  CA  . ILE A 1 258 ? -10.72  -11.294 54.698  1 12.579 ? 250  ILE A CA  1 
ATOM   1808 C  C   . ILE A 1 258 ? -9.315  -11.365 54.108  1 11.785 ? 250  ILE A C   1 
ATOM   1809 O  O   . ILE A 1 258 ? -8.768  -12.453 53.863  1 12.688 ? 250  ILE A O   1 
ATOM   1810 C  CB  . ILE A 1 258 ? -11.083 -12.537 55.543  1 13.238 ? 250  ILE A CB  1 
ATOM   1811 C  CG1 . ILE A 1 258 ? -12.612 -12.694 55.836  1 17     ? 250  ILE A CG1 1 
ATOM   1812 C  CG2 . ILE A 1 258 ? -10.206 -12.504 56.818  1 13.614 ? 250  ILE A CG2 1 
ATOM   1813 C  CD1 . ILE A 1 258 ? -12.935 -13.878 56.763  1 12.731 ? 250  ILE A CD1 1 
ATOM   1814 N  N   . HIS A 1 259 ? -8.726  -10.205 53.876  1 12.317 ? 251  HIS A N   1 
ATOM   1815 C  CA  . HIS A 1 259 ? -7.458  -10.117 53.147  1 13.789 ? 251  HIS A CA  1 
ATOM   1816 C  C   . HIS A 1 259 ? -6.247  -10.554 53.982  1 13.299 ? 251  HIS A C   1 
ATOM   1817 O  O   . HIS A 1 259 ? -5.355  -11.283 53.506  1 11.078 ? 251  HIS A O   1 
ATOM   1818 C  CB  . HIS A 1 259 ? -7.331  -8.711  52.517  1 15.829 ? 251  HIS A CB  1 
ATOM   1819 C  CG  . HIS A 1 259 ? -5.968  -8.532  51.91   1 13.839 ? 251  HIS A CG  1 
ATOM   1820 N  ND1 . HIS A 1 259 ? -5.788  -9.223  50.733  1 16.38  ? 251  HIS A ND1 1 
ATOM   1821 C  CD2 . HIS A 1 259 ? -4.821  -7.906  52.152  1 14.702 ? 251  HIS A CD2 1 
ATOM   1822 C  CE1 . HIS A 1 259 ? -4.58   -9.066  50.258  1 17.649 ? 251  HIS A CE1 1 
ATOM   1823 N  NE2 . HIS A 1 259 ? -3.967  -8.241  51.089  1 15.409 ? 251  HIS A NE2 1 
ATOM   1824 N  N   . ASP A 1 260 ? -6.224  -10.127 55.265  1 13.028 ? 252  ASP A N   1 
ATOM   1825 C  CA  . ASP A 1 260 ? -5.046  -10.295 56.085  1 13.423 ? 252  ASP A CA  1 
ATOM   1826 C  C   . ASP A 1 260 ? -5.475  -10.696 57.497  1 13.959 ? 252  ASP A C   1 
ATOM   1827 O  O   . ASP A 1 260 ? -6.656  -10.835 57.812  1 14.181 ? 252  ASP A O   1 
ATOM   1828 C  CB  . ASP A 1 260 ? -4.236  -8.996  56.085  1 12.213 ? 252  ASP A CB  1 
ATOM   1829 C  CG  . ASP A 1 260 ? -2.777  -9.081  56.536  1 13.775 ? 252  ASP A CG  1 
ATOM   1830 O  OD1 . ASP A 1 260 ? -2.331  -10.201 56.906  1 11.816 ? 252  ASP A OD1 1 
ATOM   1831 O  OD2 . ASP A 1 260 ? -2.106  -8.029  56.517  1 13.488 ? 252  ASP A OD2 1 
ATOM   1832 N  N   . CYS A 1 261 ? -4.479  -10.925 58.357  1 12.648 ? 253  CYS A N   1 
ATOM   1833 C  CA  . CYS A 1 261 ? -4.684  -11.478 59.693  1 12.572 ? 253  CYS A CA  1 
ATOM   1834 C  C   . CYS A 1 261 ? -3.516  -11.071 60.573  1 12.564 ? 253  CYS A C   1 
ATOM   1835 O  O   . CYS A 1 261 ? -2.521  -10.451 60.137  1 12.567 ? 253  CYS A O   1 
ATOM   1836 C  CB  . CYS A 1 261 ? -4.913  -12.996 59.582  1 12.926 ? 253  CYS A CB  1 
ATOM   1837 S  SG  . CYS A 1 261 ? -3.46   -13.862 58.957  1 15.931 ? 253  CYS A SG  1 
ATOM   1838 N  N   . ALA A 1 262 ? -3.65   -11.394 61.859  1 14.833 ? 254  ALA A N   1 
ATOM   1839 C  CA  . ALA A 1 262 ? -2.515  -11.278 62.757  1 14.835 ? 254  ALA A CA  1 
ATOM   1840 C  C   . ALA A 1 262 ? -2.303  -12.59  63.514  1 15.625 ? 254  ALA A C   1 
ATOM   1841 O  O   . ALA A 1 262 ? -3.278  -13.256 63.895  1 18.383 ? 254  ALA A O   1 
ATOM   1842 C  CB  . ALA A 1 262 ? -2.719  -10.093 63.681  1 14.746 ? 254  ALA A CB  1 
ATOM   1843 N  N   . LEU A 1 263 ? -1.036  -13.005 63.689  1 15.27  ? 255  LEU A N   1 
ATOM   1844 C  CA  . LEU A 1 263 ? -0.757  -14.212 64.472  1 14.488 ? 255  LEU A CA  1 
ATOM   1845 C  C   . LEU A 1 263 ? -0.222  -13.761 65.83   1 16.192 ? 255  LEU A C   1 
ATOM   1846 O  O   . LEU A 1 263 ? 0.657   -12.878 65.888  1 17.019 ? 255  LEU A O   1 
ATOM   1847 C  CB  . LEU A 1 263 ? 0.293   -15.041 63.745  1 15.083 ? 255  LEU A CB  1 
ATOM   1848 C  CG  . LEU A 1 263 ? 0.764   -16.325 64.386  1 14.45  ? 255  LEU A CG  1 
ATOM   1849 C  CD1 . LEU A 1 263 ? -0.371  -17.333 64.334  1 14.601 ? 255  LEU A CD1 1 
ATOM   1850 C  CD2 . LEU A 1 263 ? 2.048   -16.82  63.74   1 16.97  ? 255  LEU A CD2 1 
ATOM   1851 N  N   . THR A 1 264 ? -0.686  -14.472 66.864  1 14.18  ? 256  THR A N   1 
ATOM   1852 C  CA  . THR A 1 264 ? -0.209  -14.303 68.245  1 18.816 ? 256  THR A CA  1 
ATOM   1853 C  C   . THR A 1 264 ? 0.211   -15.67  68.778  1 18.564 ? 256  THR A C   1 
ATOM   1854 O  O   . THR A 1 264 ? 0.09    -16.658 68.06   1 19.421 ? 256  THR A O   1 
ATOM   1855 C  CB  . THR A 1 264 ? -1.231  -13.629 69.15   1 17.894 ? 256  THR A CB  1 
ATOM   1856 O  OG1 . THR A 1 264 ? -2.154  -14.648 69.524  1 21.234 ? 256  THR A OG1 1 
ATOM   1857 C  CG2 . THR A 1 264 ? -1.86   -12.389 68.531  1 17.823 ? 256  THR A CG2 1 
ATOM   1858 N  N   . PRO A 1 265 ? 0.751   -15.837 70.017  1 19.251 ? 257  PRO A N   1 
ATOM   1859 C  CA  . PRO A 1 265 ? 1.079   -17.185 70.462  1 18.115 ? 257  PRO A CA  1 
ATOM   1860 C  C   . PRO A 1 265 ? -0.104  -18.156 70.509  1 15.835 ? 257  PRO A C   1 
ATOM   1861 O  O   . PRO A 1 265 ? 0.045   -19.34  70.241  1 15.42  ? 257  PRO A O   1 
ATOM   1862 C  CB  . PRO A 1 265 ? 1.7     -16.942 71.86   1 17.867 ? 257  PRO A CB  1 
ATOM   1863 C  CG  . PRO A 1 265 ? 2.323   -15.553 71.685  1 20.62  ? 257  PRO A CG  1 
ATOM   1864 C  CD  . PRO A 1 265 ? 1.322   -14.805 70.904  1 20.63  ? 257  PRO A CD  1 
ATOM   1865 N  N   . ASN A 1 266 ? -1.272  -17.662 70.911  1 15.374 ? 258  ASN A N   1 
ATOM   1866 C  CA  . ASN A 1 266 ? -2.451  -18.506 71.148  1 18.217 ? 258  ASN A CA  1 
ATOM   1867 C  C   . ASN A 1 266 ? -3.601  -18.272 70.156  1 17.516 ? 258  ASN A C   1 
ATOM   1868 O  O   . ASN A 1 266 ? -4.642  -18.914 70.302  1 19.328 ? 258  ASN A O   1 
ATOM   1869 C  CB  . ASN A 1 266 ? -2.969  -18.336 72.578  1 20.439 ? 258  ASN A CB  1 
ATOM   1870 C  CG  . ASN A 1 266 ? -1.89   -18.751 73.562  1 21.154 ? 258  ASN A CG  1 
ATOM   1871 O  OD1 . ASN A 1 266 ? -1.461  -19.914 73.528  1 27.32  ? 258  ASN A OD1 1 
ATOM   1872 N  ND2 . ASN A 1 266 ? -1.355  -17.835 74.355  1 21.1   ? 258  ASN A ND2 1 
ATOM   1873 N  N   . TYR A 1 267 ? -3.452  -17.36  69.172  1 16.81  ? 259  TYR A N   1 
ATOM   1874 C  CA  . TYR A 1 267 ? -4.566  -17.024 68.282  1 15.425 ? 259  TYR A CA  1 
ATOM   1875 C  C   . TYR A 1 267 ? -4.07   -16.837 66.86   1 16.334 ? 259  TYR A C   1 
ATOM   1876 O  O   . TYR A 1 267 ? -2.944  -16.386 66.655  1 18.781 ? 259  TYR A O   1 
ATOM   1877 C  CB  . TYR A 1 267 ? -5.335  -15.73  68.6    1 15.304 ? 259  TYR A CB  1 
ATOM   1878 C  CG  . TYR A 1 267 ? -6.065  -15.821 69.938  1 17.504 ? 259  TYR A CG  1 
ATOM   1879 C  CD1 . TYR A 1 267 ? -5.414  -15.449 71.121  1 17.704 ? 259  TYR A CD1 1 
ATOM   1880 C  CD2 . TYR A 1 267 ? -7.395  -16.289 70      1 17.099 ? 259  TYR A CD2 1 
ATOM   1881 C  CE1 . TYR A 1 267 ? -6.102  -15.519 72.33   1 21.265 ? 259  TYR A CE1 1 
ATOM   1882 C  CE2 . TYR A 1 267 ? -8.063  -16.401 71.204  1 18.097 ? 259  TYR A CE2 1 
ATOM   1883 C  CZ  . TYR A 1 267 ? -7.402  -16.012 72.369  1 21.227 ? 259  TYR A CZ  1 
ATOM   1884 O  OH  . TYR A 1 267 ? -8.049  -16.1   73.556  1 22.538 ? 259  TYR A OH  1 
ATOM   1885 N  N   . LEU A 1 268 ? -4.954  -17.143 65.91   1 15.376 ? 260  LEU A N   1 
ATOM   1886 C  CA  . LEU A 1 268 ? -4.939  -16.481 64.615  1 13.575 ? 260  LEU A CA  1 
ATOM   1887 C  C   . LEU A 1 268 ? -6.104  -15.491 64.613  1 16.53  ? 260  LEU A C   1 
ATOM   1888 O  O   . LEU A 1 268 ? -7.251  -15.876 64.922  1 18.787 ? 260  LEU A O   1 
ATOM   1889 C  CB  . LEU A 1 268 ? -5.019  -17.504 63.484  1 14.872 ? 260  LEU A CB  1 
ATOM   1890 C  CG  . LEU A 1 268 ? -4.938  -16.854 62.084  1 13.422 ? 260  LEU A CG  1 
ATOM   1891 C  CD1 . LEU A 1 268 ? -3.526  -16.282 61.921  1 14.082 ? 260  LEU A CD1 1 
ATOM   1892 C  CD2 . LEU A 1 268 ? -5.326  -17.913 61.028  1 15.159 ? 260  LEU A CD2 1 
ATOM   1893 N  N   . VAL A 1 269 ? -5.849  -14.225 64.215  1 14.886 ? 261  VAL A N   1 
ATOM   1894 C  CA  . VAL A 1 269 ? -6.946  -13.251 64.243  1 15.985 ? 261  VAL A CA  1 
ATOM   1895 C  C   . VAL A 1 269 ? -7.242  -12.835 62.804  1 14.641 ? 261  VAL A C   1 
ATOM   1896 O  O   . VAL A 1 269 ? -6.384  -12.203 62.203  1 14.89  ? 261  VAL A O   1 
ATOM   1897 C  CB  . VAL A 1 269 ? -6.695  -12.046 65.157  1 14.748 ? 261  VAL A CB  1 
ATOM   1898 C  CG1 . VAL A 1 269 ? -7.903  -11.13  65.279  1 13.097 ? 261  VAL A CG1 1 
ATOM   1899 C  CG2 . VAL A 1 269 ? -6.233  -12.498 66.557  1 16.973 ? 261  VAL A CG2 1 
ATOM   1900 N  N   . LEU A 1 270 ? -8.468  -13.086 62.339  1 17.714 ? 262  LEU A N   1 
ATOM   1901 C  CA  . LEU A 1 270 ? -8.817  -12.737 60.927  1 15.308 ? 262  LEU A CA  1 
ATOM   1902 C  C   . LEU A 1 270 ? -9.365  -11.308 60.882  1 16.783 ? 262  LEU A C   1 
ATOM   1903 O  O   . LEU A 1 270 ? -10.1   -10.918 61.778  1 17.766 ? 262  LEU A O   1 
ATOM   1904 C  CB  . LEU A 1 270 ? -9.868  -13.716 60.43   1 17.568 ? 262  LEU A CB  1 
ATOM   1905 C  CG  . LEU A 1 270 ? -9.529  -15.208 60.484  1 19.642 ? 262  LEU A CG  1 
ATOM   1906 C  CD1 . LEU A 1 270 ? -10.585 -15.922 59.609  1 19.221 ? 262  LEU A CD1 1 
ATOM   1907 C  CD2 . LEU A 1 270 ? -8.149  -15.504 59.973  1 18.111 ? 262  LEU A CD2 1 
ATOM   1908 N  N   . MET A 1 271 ? -8.996  -10.495 59.879  1 13.13  ? 263  MET A N   1 
ATOM   1909 C  CA  . MET A 1 271 ? -9.446  -9.108  59.796  1 11.393 ? 263  MET A CA  1 
ATOM   1910 C  C   . MET A 1 271 ? -10.414 -8.935  58.636  1 12.167 ? 263  MET A C   1 
ATOM   1911 O  O   . MET A 1 271 ? -10.018 -9.166  57.475  1 12.52  ? 263  MET A O   1 
ATOM   1912 C  CB  . MET A 1 271 ? -8.198  -8.214  59.708  1 12.914 ? 263  MET A CB  1 
ATOM   1913 C  CG  . MET A 1 271 ? -8.402  -6.715  59.559  1 15.923 ? 263  MET A CG  1 
ATOM   1914 S  SD  . MET A 1 271 ? -6.815  -5.867  59.767  1 17.448 ? 263  MET A SD  1 
ATOM   1915 C  CE  . MET A 1 271 ? -6.099  -6.222  58.144  1 17.639 ? 263  MET A CE  1 
ATOM   1916 N  N   . LEU A 1 272 ? -11.688 -8.598  58.956  1 11.712 ? 264  LEU A N   1 
ATOM   1917 C  CA  . LEU A 1 272 ? -12.751 -8.505  57.957  1 14.529 ? 264  LEU A CA  1 
ATOM   1918 C  C   . LEU A 1 272 ? -12.852 -7.06   57.511  1 15.537 ? 264  LEU A C   1 
ATOM   1919 O  O   . LEU A 1 272 ? -13.129 -6.173  58.321  1 14.253 ? 264  LEU A O   1 
ATOM   1920 C  CB  . LEU A 1 272 ? -14.131 -9.031  58.397  1 13.036 ? 264  LEU A CB  1 
ATOM   1921 C  CG  . LEU A 1 272 ? -14.275 -10.554 58.55   1 12.336 ? 264  LEU A CG  1 
ATOM   1922 C  CD1 . LEU A 1 272 ? -13.16  -11.252 59.398  1 14.921 ? 264  LEU A CD1 1 
ATOM   1923 C  CD2 . LEU A 1 272 ? -15.709 -10.773 59.077  1 13.919 ? 264  LEU A CD2 1 
ATOM   1924 N  N   . TRP A 1 273 ? -12.742 -6.849  56.193  1 13.974 ? 265  TRP A N   1 
ATOM   1925 C  CA  . TRP A 1 273 ? -13.028 -5.56   55.575  1 13.041 ? 265  TRP A CA  1 
ATOM   1926 C  C   . TRP A 1 273 ? -14.538 -5.483  55.327  1 13.489 ? 265  TRP A C   1 
ATOM   1927 O  O   . TRP A 1 273 ? -15.182 -6.523  55.146  1 14.437 ? 265  TRP A O   1 
ATOM   1928 C  CB  . TRP A 1 273 ? -12.305 -5.46   54.199  1 11.526 ? 265  TRP A CB  1 
ATOM   1929 C  CG  . TRP A 1 273 ? -10.782 -5.412  54.264  1 12.403 ? 265  TRP A CG  1 
ATOM   1930 C  CD1 . TRP A 1 273 ? -9.939  -5.317  55.33   1 13.632 ? 265  TRP A CD1 1 
ATOM   1931 C  CD2 . TRP A 1 273 ? -9.96   -5.385  53.089  1 13.151 ? 265  TRP A CD2 1 
ATOM   1932 N  NE1 . TRP A 1 273 ? -8.624  -5.278  54.903  1 15.391 ? 265  TRP A NE1 1 
ATOM   1933 C  CE2 . TRP A 1 273 ? -8.625  -5.295  53.516  1 12.772 ? 265  TRP A CE2 1 
ATOM   1934 C  CE3 . TRP A 1 273 ? -10.253 -5.434  51.706  1 10.901 ? 265  TRP A CE3 1 
ATOM   1935 C  CZ2 . TRP A 1 273 ? -7.572  -5.247  52.623  1 12.893 ? 265  TRP A CZ2 1 
ATOM   1936 C  CZ3 . TRP A 1 273 ? -9.194  -5.346  50.809  1 10.903 ? 265  TRP A CZ3 1 
ATOM   1937 C  CH2 . TRP A 1 273 ? -7.865  -5.251  51.265  1 12.805 ? 265  TRP A CH2 1 
ATOM   1938 N  N   . PRO A 1 274 ? -15.161 -4.291  55.315  1 11.072 ? 266  PRO A N   1 
ATOM   1939 C  CA  . PRO A 1 274 ? -16.6   -4.19   55.098  1 13.224 ? 266  PRO A CA  1 
ATOM   1940 C  C   . PRO A 1 274 ? -16.967 -4.24   53.603  1 15.525 ? 266  PRO A C   1 
ATOM   1941 O  O   . PRO A 1 274 ? -17.539 -3.284  53.073  1 15.486 ? 266  PRO A O   1 
ATOM   1942 C  CB  . PRO A 1 274 ? -16.915 -2.839  55.68   1 13.972 ? 266  PRO A CB  1 
ATOM   1943 C  CG  . PRO A 1 274 ? -15.632 -2.005  55.389  1 12.03  ? 266  PRO A CG  1 
ATOM   1944 C  CD  . PRO A 1 274 ? -14.506 -2.986  55.503  1 12.724 ? 266  PRO A CD  1 
ATOM   1945 N  N   . PHE A 1 275 ? -16.567 -5.349  52.945  1 16.07  ? 267  PHE A N   1 
ATOM   1946 C  CA  . PHE A 1 275 ? -17.113 -5.671  51.631  1 15.027 ? 267  PHE A CA  1 
ATOM   1947 C  C   . PHE A 1 275 ? -17.914 -6.954  51.79   1 16.008 ? 267  PHE A C   1 
ATOM   1948 O  O   . PHE A 1 275 ? -17.523 -7.775  52.626  1 16.818 ? 267  PHE A O   1 
ATOM   1949 C  CB  . PHE A 1 275 ? -16.026 -5.95   50.574  1 14.622 ? 267  PHE A CB  1 
ATOM   1950 C  CG  . PHE A 1 275 ? -15.172 -4.743  50.276  1 15.656 ? 267  PHE A CG  1 
ATOM   1951 C  CD1 . PHE A 1 275 ? -14.099 -4.395  51.119  1 15.692 ? 267  PHE A CD1 1 
ATOM   1952 C  CD2 . PHE A 1 275 ? -15.421 -3.978  49.131  1 12.831 ? 267  PHE A CD2 1 
ATOM   1953 C  CE1 . PHE A 1 275 ? -13.267 -3.278  50.838  1 14.427 ? 267  PHE A CE1 1 
ATOM   1954 C  CE2 . PHE A 1 275 ? -14.638 -2.865  48.881  1 14.961 ? 267  PHE A CE2 1 
ATOM   1955 C  CZ  . PHE A 1 275 ? -13.492 -2.564  49.657  1 16.022 ? 267  PHE A CZ  1 
ATOM   1956 N  N   . GLU A 1 276 ? -18.977 -7.119  50.977  1 13.292 ? 268  GLU A N   1 
ATOM   1957 C  CA  . GLU A 1 276 ? -19.749 -8.349  51.012  1 12.221 ? 268  GLU A CA  1 
ATOM   1958 C  C   . GLU A 1 276 ? -19.848 -8.88   49.591  1 11.985 ? 268  GLU A C   1 
ATOM   1959 O  O   . GLU A 1 276 ? -19.879 -8.103  48.673  1 12.912 ? 268  GLU A O   1 
ATOM   1960 C  CB  . GLU A 1 276 ? -21.131 -8.041  51.584  1 13.436 ? 268  GLU A CB  1 
ATOM   1961 C  CG  . GLU A 1 276 ? -22.076 -9.247  51.708  1 17.049 ? 268  GLU A CG  1 
ATOM   1962 C  CD  . GLU A 1 276 ? -23.206 -9.173  52.741  1 16.624 ? 268  GLU A CD  1 
ATOM   1963 O  OE1 . GLU A 1 276 ? -23.614 -8.048  53.098  1 16.615 ? 268  GLU A OE1 1 
ATOM   1964 O  OE2 . GLU A 1 276 ? -23.745 -10.255 53.144  1 17.389 ? 268  GLU A OE2 1 
ATOM   1965 N  N   . ALA A 1 277 ? -19.761 -10.21  49.428  1 12.823 ? 269  ALA A N   1 
ATOM   1966 C  CA  . ALA A 1 277 ? -19.892 -10.87  48.123  1 13.863 ? 269  ALA A CA  1 
ATOM   1967 C  C   . ALA A 1 277 ? -21.341 -11.292 47.933  1 16.958 ? 269  ALA A C   1 
ATOM   1968 O  O   . ALA A 1 277 ? -22.002 -11.675 48.885  1 19.477 ? 269  ALA A O   1 
ATOM   1969 C  CB  . ALA A 1 277 ? -19.048 -12.126 48.083  1 11.626 ? 269  ALA A CB  1 
ATOM   1970 N  N   . ASN A 1 278 ? -21.802 -11.32  46.681  1 15.72  ? 270  ASN A N   1 
ATOM   1971 C  CA  . ASN A 1 278 ? -23.201 -11.6   46.398  1 15.381 ? 270  ASN A CA  1 
ATOM   1972 C  C   . ASN A 1 278 ? -23.253 -12.345 45.067  1 14.675 ? 270  ASN A C   1 
ATOM   1973 O  O   . ASN A 1 278 ? -22.882 -11.771 44.033  1 14.774 ? 270  ASN A O   1 
ATOM   1974 C  CB  . ASN A 1 278 ? -24.003 -10.285 46.336  1 15.974 ? 270  ASN A CB  1 
ATOM   1975 C  CG  . ASN A 1 278 ? -25.465 -10.552 46.027  1 17.062 ? 270  ASN A CG  1 
ATOM   1976 O  OD1 . ASN A 1 278 ? -25.867 -10.735 44.866  1 13.712 ? 270  ASN A OD1 1 
ATOM   1977 N  ND2 . ASN A 1 278 ? -26.236 -10.531 47.091  1 19.141 ? 270  ASN A ND2 1 
ATOM   1978 N  N   . LEU A 1 279 ? -23.78  -13.581 45.115  1 15.561 ? 271  LEU A N   1 
ATOM   1979 C  CA  . LEU A 1 279 ? -23.774 -14.459 43.947  1 16.716 ? 271  LEU A CA  1 
ATOM   1980 C  C   . LEU A 1 279 ? -24.663 -13.922 42.834  1 18.164 ? 271  LEU A C   1 
ATOM   1981 O  O   . LEU A 1 279 ? -24.286 -13.952 41.627  1 17.705 ? 271  LEU A O   1 
ATOM   1982 C  CB  . LEU A 1 279 ? -24.072 -15.907 44.402  1 15.311 ? 271  LEU A CB  1 
ATOM   1983 C  CG  . LEU A 1 279 ? -23.873 -16.989 43.326  1 16.708 ? 271  LEU A CG  1 
ATOM   1984 C  CD1 . LEU A 1 279 ? -22.382 -17.299 42.945  1 17.247 ? 271  LEU A CD1 1 
ATOM   1985 C  CD2 . LEU A 1 279 ? -24.635 -18.3   43.754  1 17.219 ? 271  LEU A CD2 1 
ATOM   1986 N  N   . GLU A 1 280 ? -25.848 -13.385 43.24   1 18.603 ? 272  GLU A N   1 
ATOM   1987 C  CA  . GLU A 1 280 ? -26.778 -12.889 42.234  1 20.733 ? 272  GLU A CA  1 
ATOM   1988 C  C   . GLU A 1 280 ? -26.198 -11.679 41.502  1 16.389 ? 272  GLU A C   1 
ATOM   1989 O  O   . GLU A 1 280 ? -26.235 -11.694 40.286  1 17.666 ? 272  GLU A O   1 
ATOM   1990 C  CB  . GLU A 1 280 ? -28.189 -12.887 42.81   1 26.464 ? 272  GLU A CB  1 
ATOM   1991 C  CG  . GLU A 1 280 ? -28.712 -14.329 42.833  1 32.715 ? 272  GLU A CG  1 
ATOM   1992 C  CD  . GLU A 1 280 ? -29.442 -14.838 41.603  1 37.067 ? 272  GLU A CD  1 
ATOM   1993 O  OE1 . GLU A 1 280 ? -30.632 -15.116 41.881  1 54.644 ? 272  GLU A OE1 1 
ATOM   1994 O  OE2 . GLU A 1 280 ? -28.972 -14.933 40.419  1 37.016 ? 272  GLU A OE2 1 
ATOM   1995 N  N   . ARG A 1 281 ? -25.547 -10.772 42.228  1 15.505 ? 273  ARG A N   1 
ATOM   1996 C  CA  . ARG A 1 281 ? -24.737 -9.713  41.61   1 16.463 ? 273  ARG A CA  1 
ATOM   1997 C  C   . ARG A 1 281 ? -23.644 -10.235 40.664  1 16.544 ? 273  ARG A C   1 
ATOM   1998 O  O   . ARG A 1 281 ? -23.493 -9.68   39.559  1 17.808 ? 273  ARG A O   1 
ATOM   1999 C  CB  . ARG A 1 281 ? -24.07  -8.825  42.643  1 18.288 ? 273  ARG A CB  1 
ATOM   2000 C  CG  . ARG A 1 281 ? -23.428 -7.606  41.982  1 18.386 ? 273  ARG A CG  1 
ATOM   2001 C  CD  . ARG A 1 281 ? -22.846 -6.652  43.016  1 20.059 ? 273  ARG A CD  1 
ATOM   2002 N  NE  . ARG A 1 281 ? -21.904 -7.38   43.899  1 17.173 ? 273  ARG A NE  1 
ATOM   2003 C  CZ  . ARG A 1 281 ? -22.071 -7.339  45.236  1 15.559 ? 273  ARG A CZ  1 
ATOM   2004 N  NH1 . ARG A 1 281 ? -23.15  -6.754  45.782  1 13.919 ? 273  ARG A NH1 1 
ATOM   2005 N  NH2 . ARG A 1 281 ? -21.206 -7.955  45.987  1 16.022 ? 273  ARG A NH2 1 
ATOM   2006 N  N   . MET A 1 282 ? -22.958 -11.331 41.044  1 14.327 ? 274  MET A N   1 
ATOM   2007 C  CA  . MET A 1 282 ? -21.938 -11.856 40.165  1 14.656 ? 274  MET A CA  1 
ATOM   2008 C  C   . MET A 1 282 ? -22.585 -12.434 38.923  1 14.052 ? 274  MET A C   1 
ATOM   2009 O  O   . MET A 1 282 ? -22.105 -12.23  37.812  1 15.12  ? 274  MET A O   1 
ATOM   2010 C  CB  . MET A 1 282 ? -21.097 -12.906 40.89   1 14.402 ? 274  MET A CB  1 
ATOM   2011 C  CG  . MET A 1 282 ? -20.156 -12.194 41.929  1 14.957 ? 274  MET A CG  1 
ATOM   2012 S  SD  . MET A 1 282 ? -19.181 -13.561 42.611  1 18.959 ? 274  MET A SD  1 
ATOM   2013 C  CE  . MET A 1 282 ? -19.367 -13.365 44.388  1 14.52  ? 274  MET A CE  1 
ATOM   2014 N  N   . LYS A 1 283 ? -23.721 -13.117 39.118  1 17.752 ? 275  LYS A N   1 
ATOM   2015 C  CA  . LYS A 1 283 ? -24.36  -13.771 38      1 13.841 ? 275  LYS A CA  1 
ATOM   2016 C  C   . LYS A 1 283 ? -24.778 -12.713 37.004  1 18.027 ? 275  LYS A C   1 
ATOM   2017 O  O   . LYS A 1 283 ? -24.724 -12.956 35.793  1 14.467 ? 275  LYS A O   1 
ATOM   2018 C  CB  . LYS A 1 283 ? -25.495 -14.684 38.436  1 16.2   ? 275  LYS A CB  1 
ATOM   2019 C  CG  . LYS A 1 283 ? -25.007 -15.968 39.074  1 17.153 ? 275  LYS A CG  1 
ATOM   2020 C  CD  . LYS A 1 283 ? -26.262 -16.82  39.336  1 20.398 ? 275  LYS A CD  1 
ATOM   2021 C  CE  . LYS A 1 283 ? -25.708 -18.17  39.864  1 20.944 ? 275  LYS A CE  1 
ATOM   2022 N  NZ  . LYS A 1 283 ? -26.796 -19.131 40.087  1 29.384 ? 275  LYS A NZ  1 
ATOM   2023 N  N   . ALA A 1 284 ? -25.192 -11.554 37.539  1 18.316 ? 276  ALA A N   1 
ATOM   2024 C  CA  . ALA A 1 284 ? -25.632 -10.415 36.737  1 18.177 ? 276  ALA A CA  1 
ATOM   2025 C  C   . ALA A 1 284 ? -24.474 -9.629  36.108  1 18.953 ? 276  ALA A C   1 
ATOM   2026 O  O   . ALA A 1 284 ? -24.738 -8.599  35.465  1 19.84  ? 276  ALA A O   1 
ATOM   2027 C  CB  . ALA A 1 284 ? -26.486 -9.53   37.634  1 17.617 ? 276  ALA A CB  1 
ATOM   2028 N  N   . GLY A 1 285 ? -23.219 -10.119 36.233  1 14.898 ? 277  GLY A N   1 
ATOM   2029 C  CA  . GLY A 1 285 ? -22.088 -9.49   35.575  1 15.144 ? 277  GLY A CA  1 
ATOM   2030 C  C   . GLY A 1 285 ? -21.534 -8.299  36.35   1 15.267 ? 277  GLY A C   1 
ATOM   2031 O  O   . GLY A 1 285 ? -20.741 -7.539  35.797  1 13.21  ? 277  GLY A O   1 
ATOM   2032 N  N   . GLY A 1 286 ? -21.895 -8.186  37.654  1 15.369 ? 278  GLY A N   1 
ATOM   2033 C  CA  . GLY A 1 286 ? -21.345 -7.137  38.493  1 13.826 ? 278  GLY A CA  1 
ATOM   2034 C  C   . GLY A 1 286 ? -20.097 -7.636  39.245  1 17.831 ? 278  GLY A C   1 
ATOM   2035 O  O   . GLY A 1 286 ? -19.69  -8.776  39.1    1 17.414 ? 278  GLY A O   1 
ATOM   2036 N  N   . HIS A 1 287 ? -19.459 -6.753  40.018  1 17.494 ? 279  HIS A N   1 
ATOM   2037 C  CA  . HIS A 1 287 ? -18.298 -7.053  40.839  1 15.065 ? 279  HIS A CA  1 
ATOM   2038 C  C   . HIS A 1 287 ? -18.609 -8.096  41.909  1 16.026 ? 279  HIS A C   1 
ATOM   2039 O  O   . HIS A 1 287 ? -19.716 -8.199  42.423  1 12.317 ? 279  HIS A O   1 
ATOM   2040 C  CB  . HIS A 1 287 ? -17.74  -5.768  41.445  1 15.35  ? 279  HIS A CB  1 
ATOM   2041 C  CG  . HIS A 1 287 ? -16.837 -5.058  40.445  1 19.752 ? 279  HIS A CG  1 
ATOM   2042 N  ND1 . HIS A 1 287 ? -16.933 -3.719  40.094  1 22.215 ? 279  HIS A ND1 1 
ATOM   2043 C  CD2 . HIS A 1 287 ? -15.741 -5.536  39.803  1 17.794 ? 279  HIS A CD2 1 
ATOM   2044 C  CE1 . HIS A 1 287 ? -15.939 -3.41   39.258  1 17.285 ? 279  HIS A CE1 1 
ATOM   2045 N  NE2 . HIS A 1 287 ? -15.234 -4.523  39.044  1 23.054 ? 279  HIS A NE2 1 
ATOM   2046 N  N   . HIS A 1 288 ? -17.562 -8.85   42.249  1 12.773 ? 280  HIS A N   1 
ATOM   2047 C  CA  . HIS A 1 288 ? -17.585 -9.839  43.313  1 14.03  ? 280  HIS A CA  1 
ATOM   2048 C  C   . HIS A 1 288 ? -17.917 -9.155  44.64   1 11.448 ? 280  HIS A C   1 
ATOM   2049 O  O   . HIS A 1 288 ? -18.797 -9.599  45.346  1 15.002 ? 280  HIS A O   1 
ATOM   2050 C  CB  . HIS A 1 288 ? -16.181 -10.458 43.487  1 12.18  ? 280  HIS A CB  1 
ATOM   2051 C  CG  . HIS A 1 288 ? -16.177 -11.709 44.393  1 13.959 ? 280  HIS A CG  1 
ATOM   2052 N  ND1 . HIS A 1 288 ? -16.113 -13.025 43.951  1 9.548  ? 280  HIS A ND1 1 
ATOM   2053 C  CD2 . HIS A 1 288 ? -16.055 -11.752 45.77   1 13.65  ? 280  HIS A CD2 1 
ATOM   2054 C  CE1 . HIS A 1 288 ? -16.005 -13.812 45.007  1 11.849 ? 280  HIS A CE1 1 
ATOM   2055 N  NE2 . HIS A 1 288 ? -16.028 -13.067 46.133  1 9.928  ? 280  HIS A NE2 1 
ATOM   2056 N  N   . TRP A 1 289 ? -17.288 -8.003  44.873  1 11.713 ? 281  TRP A N   1 
ATOM   2057 C  CA  . TRP A 1 289 ? -17.351 -7.354  46.164  1 10.874 ? 281  TRP A CA  1 
ATOM   2058 C  C   . TRP A 1 289 ? -18.145 -6.054  45.975  1 13.422 ? 281  TRP A C   1 
ATOM   2059 O  O   . TRP A 1 289 ? -18.022 -5.413  44.922  1 16.277 ? 281  TRP A O   1 
ATOM   2060 C  CB  . TRP A 1 289 ? -15.926 -6.996  46.658  1 10.811 ? 281  TRP A CB  1 
ATOM   2061 C  CG  . TRP A 1 289 ? -15.074 -8.196  46.989  1 11.467 ? 281  TRP A CG  1 
ATOM   2062 C  CD1 . TRP A 1 289 ? -13.905 -8.596  46.384  1 13.264 ? 281  TRP A CD1 1 
ATOM   2063 C  CD2 . TRP A 1 289 ? -15.309 -9.141  48.054  1 12.445 ? 281  TRP A CD2 1 
ATOM   2064 N  NE1 . TRP A 1 289 ? -13.406 -9.74   46.946  1 11.63  ? 281  TRP A NE1 1 
ATOM   2065 C  CE2 . TRP A 1 289 ? -14.214 -10.075 48.017  1 14.267 ? 281  TRP A CE2 1 
ATOM   2066 C  CE3 . TRP A 1 289 ? -16.323 -9.302  49.027  1 13.944 ? 281  TRP A CE3 1 
ATOM   2067 C  CZ2 . TRP A 1 289 ? -14.159 -11.15  48.914  1 13.135 ? 281  TRP A CZ2 1 
ATOM   2068 C  CZ3 . TRP A 1 289 ? -16.245 -10.343 49.923  1 13.541 ? 281  TRP A CZ3 1 
ATOM   2069 C  CH2 . TRP A 1 289 ? -15.185 -11.269 49.848  1 13.33  ? 281  TRP A CH2 1 
ATOM   2070 N  N   . ALA A 1 290 ? -18.76  -5.61   47.072  1 12.54  ? 282  ALA A N   1 
ATOM   2071 C  CA  . ALA A 1 290 ? -19.348 -4.267  47.141  1 12.133 ? 282  ALA A CA  1 
ATOM   2072 C  C   . ALA A 1 290 ? -19.096 -3.745  48.546  1 13.432 ? 282  ALA A C   1 
ATOM   2073 O  O   . ALA A 1 290 ? -19.41  -4.416  49.514  1 13.453 ? 282  ALA A O   1 
ATOM   2074 C  CB  . ALA A 1 290 ? -20.854 -4.328  46.881  1 11.837 ? 282  ALA A CB  1 
ATOM   2075 N  N   . TYR A 1 291 ? -18.537 -2.523  48.632  1 13.902 ? 283  TYR A N   1 
ATOM   2076 C  CA  . TYR A 1 291 ? -18.269 -1.904  49.918  1 15.938 ? 283  TYR A CA  1 
ATOM   2077 C  C   . TYR A 1 291 ? -19.607 -1.645  50.619  1 15.862 ? 283  TYR A C   1 
ATOM   2078 O  O   . TYR A 1 291 ? -20.572 -1.315  49.972  1 18.081 ? 283  TYR A O   1 
ATOM   2079 C  CB  . TYR A 1 291 ? -17.539 -0.561  49.706  1 15.842 ? 283  TYR A CB  1 
ATOM   2080 C  CG  . TYR A 1 291 ? -16.992 0.027   50.997  1 14.162 ? 283  TYR A CG  1 
ATOM   2081 C  CD1 . TYR A 1 291 ? -15.681 -0.282  51.428  1 13.653 ? 283  TYR A CD1 1 
ATOM   2082 C  CD2 . TYR A 1 291 ? -17.748 0.921   51.747  1 17.113 ? 283  TYR A CD2 1 
ATOM   2083 C  CE1 . TYR A 1 291 ? -15.205 0.224   52.625  1 13.142 ? 283  TYR A CE1 1 
ATOM   2084 C  CE2 . TYR A 1 291 ? -17.266 1.445   52.943  1 15.134 ? 283  TYR A CE2 1 
ATOM   2085 C  CZ  . TYR A 1 291 ? -15.979 1.108   53.361  1 14.293 ? 283  TYR A CZ  1 
ATOM   2086 O  OH  . TYR A 1 291 ? -15.472 1.569   54.574  1 15.762 ? 283  TYR A OH  1 
ATOM   2087 N  N   . ASP A 1 292 ? -19.618 -1.797  51.963  1 16.008 ? 284  ASP A N   1 
ATOM   2088 C  CA  . ASP A 1 292 ? -20.832 -1.545  52.693  1 18.516 ? 284  ASP A CA  1 
ATOM   2089 C  C   . ASP A 1 292 ? -20.521 -0.672  53.888  1 16.782 ? 284  ASP A C   1 
ATOM   2090 O  O   . ASP A 1 292 ? -19.971 -1.184  54.843  1 14.71  ? 284  ASP A O   1 
ATOM   2091 C  CB  . ASP A 1 292 ? -21.508 -2.858  53.089  1 18.893 ? 284  ASP A CB  1 
ATOM   2092 C  CG  . ASP A 1 292 ? -22.834 -2.778  53.836  1 19.544 ? 284  ASP A CG  1 
ATOM   2093 O  OD1 . ASP A 1 292 ? -23.254 -1.682  54.217  1 19.213 ? 284  ASP A OD1 1 
ATOM   2094 O  OD2 . ASP A 1 292 ? -23.485 -3.844  53.966  1 17.731 ? 284  ASP A OD2 1 
ATOM   2095 N  N   . TYR A 1 293 ? -20.94  0.597   53.853  1 17.24  ? 285  TYR A N   1 
ATOM   2096 C  CA  . TYR A 1 293 ? -20.718 1.483   55.007  1 17.592 ? 285  TYR A CA  1 
ATOM   2097 C  C   . TYR A 1 293 ? -21.323 0.99    56.324  1 18.464 ? 285  TYR A C   1 
ATOM   2098 O  O   . TYR A 1 293 ? -20.955 1.507   57.393  1 15.568 ? 285  TYR A O   1 
ATOM   2099 C  CB  . TYR A 1 293 ? -21.255 2.88    54.636  1 19.184 ? 285  TYR A CB  1 
ATOM   2100 C  CG  . TYR A 1 293 ? -20.287 3.562   53.7    1 17.168 ? 285  TYR A CG  1 
ATOM   2101 C  CD1 . TYR A 1 293 ? -19.22  4.319   54.197  1 18.237 ? 285  TYR A CD1 1 
ATOM   2102 C  CD2 . TYR A 1 293 ? -20.475 3.493   52.306  1 19.305 ? 285  TYR A CD2 1 
ATOM   2103 C  CE1 . TYR A 1 293 ? -18.307 4.904   53.341  1 23.517 ? 285  TYR A CE1 1 
ATOM   2104 C  CE2 . TYR A 1 293 ? -19.586 4.121   51.451  1 20.253 ? 285  TYR A CE2 1 
ATOM   2105 C  CZ  . TYR A 1 293 ? -18.51  4.82    51.966  1 27.022 ? 285  TYR A CZ  1 
ATOM   2106 O  OH  . TYR A 1 293 ? -17.675 5.367   51.018  1 30.957 ? 285  TYR A OH  1 
ATOM   2107 N  N   . THR A 1 294 ? -22.338 0.104   56.269  1 22.111 ? 286  THR A N   1 
ATOM   2108 C  CA  . THR A 1 294 ? -23.051 -0.338  57.47   1 23.05  ? 286  THR A CA  1 
ATOM   2109 C  C   . THR A 1 294 ? -22.316 -1.495  58.151  1 24.692 ? 286  THR A C   1 
ATOM   2110 O  O   . THR A 1 294 ? -22.65  -1.86   59.286  1 22.896 ? 286  THR A O   1 
ATOM   2111 C  CB  . THR A 1 294 ? -24.535 -0.676  57.198  1 22.378 ? 286  THR A CB  1 
ATOM   2112 O  OG1 . THR A 1 294 ? -24.708 -1.887  56.461  1 23.305 ? 286  THR A OG1 1 
ATOM   2113 C  CG2 . THR A 1 294 ? -25.26  0.489   56.55   1 22.624 ? 286  THR A CG2 1 
ATOM   2114 N  N   . LYS A 1 295 ? -21.331 -2.081  57.455  1 20.114 ? 287  LYS A N   1 
ATOM   2115 C  CA  . LYS A 1 295 ? -20.581 -3.173  58.068  1 21.14  ? 287  LYS A CA  1 
ATOM   2116 C  C   . LYS A 1 295 ? -19.473 -2.638  58.971  1 18.235 ? 287  LYS A C   1 
ATOM   2117 O  O   . LYS A 1 295 ? -18.652 -1.84   58.538  1 18.86  ? 287  LYS A O   1 
ATOM   2118 C  CB  . LYS A 1 295 ? -19.975 -4.098  57.013  1 23.72  ? 287  LYS A CB  1 
ATOM   2119 C  CG  . LYS A 1 295 ? -20.968 -4.955  56.314  1 23.513 ? 287  LYS A CG  1 
ATOM   2120 C  CD  . LYS A 1 295 ? -21.517 -6.142  57.087  1 27.787 ? 287  LYS A CD  1 
ATOM   2121 C  CE  . LYS A 1 295 ? -22.527 -6.824  56.159  1 29.509 ? 287  LYS A CE  1 
ATOM   2122 N  NZ  . LYS A 1 295 ? -23.266 -7.898  56.812  1 35.282 ? 287  LYS A NZ  1 
ATOM   2123 N  N   . PRO A 1 296 ? -19.394 -3.049  60.263  1 15.762 ? 288  PRO A N   1 
ATOM   2124 C  CA  . PRO A 1 296 ? -18.301 -2.606  61.12   1 17.201 ? 288  PRO A CA  1 
ATOM   2125 C  C   . PRO A 1 296 ? -17.083 -3.468  60.803  1 18.579 ? 288  PRO A C   1 
ATOM   2126 O  O   . PRO A 1 296 ? -17.253 -4.617  60.365  1 15.57  ? 288  PRO A O   1 
ATOM   2127 C  CB  . PRO A 1 296 ? -18.751 -2.91   62.547  1 15.479 ? 288  PRO A CB  1 
ATOM   2128 C  CG  . PRO A 1 296 ? -19.739 -4.068  62.35   1 15.058 ? 288  PRO A CG  1 
ATOM   2129 C  CD  . PRO A 1 296 ? -20.275 -4.039  60.916  1 17.483 ? 288  PRO A CD  1 
ATOM   2130 N  N   . ILE A 1 297 ? -15.893 -2.913  60.976  1 17.259 ? 289  ILE A N   1 
ATOM   2131 C  CA  . ILE A 1 297 ? -14.693 -3.726  61.022  1 19.346 ? 289  ILE A CA  1 
ATOM   2132 C  C   . ILE A 1 297 ? -14.913 -4.825  62.061  1 18.72  ? 289  ILE A C   1 
ATOM   2133 O  O   . ILE A 1 297 ? -15.364 -4.538  63.18   1 18.62  ? 289  ILE A O   1 
ATOM   2134 C  CB  . ILE A 1 297 ? -13.443 -2.86   61.301  1 16.958 ? 289  ILE A CB  1 
ATOM   2135 C  CG1 . ILE A 1 297 ? -13.203 -1.887  60.105  1 17.634 ? 289  ILE A CG1 1 
ATOM   2136 C  CG2 . ILE A 1 297 ? -12.205 -3.749  61.629  1 14.735 ? 289  ILE A CG2 1 
ATOM   2137 C  CD1 . ILE A 1 297 ? -12.347 -0.685  60.478  1 24.663 ? 289  ILE A CD1 1 
ATOM   2138 N  N   . THR A 1 298 ? -14.674 -6.07   61.63   1 20.219 ? 290  THR A N   1 
ATOM   2139 C  CA  . THR A 1 298 ? -14.952 -7.279  62.375  1 18.073 ? 290  THR A CA  1 
ATOM   2140 C  C   . THR A 1 298 ? -13.674 -8.134  62.372  1 22.215 ? 290  THR A C   1 
ATOM   2141 O  O   . THR A 1 298 ? -12.928 -8.157  61.395  1 24.777 ? 290  THR A O   1 
ATOM   2142 C  CB  . THR A 1 298 ? -16.154 -7.964  61.735  1 19.219 ? 290  THR A CB  1 
ATOM   2143 O  OG1 . THR A 1 298 ? -17.193 -6.999  61.832  1 18.527 ? 290  THR A OG1 1 
ATOM   2144 C  CG2 . THR A 1 298 ? -16.58  -9.224  62.472  1 21.685 ? 290  THR A CG2 1 
ATOM   2145 N  N   . TRP A 1 299 ? -13.384 -8.732  63.544  1 20.433 ? 291  TRP A N   1 
ATOM   2146 C  CA  . TRP A 1 299 ? -12.257 -9.61   63.766  1 19.178 ? 291  TRP A CA  1 
ATOM   2147 C  C   . TRP A 1 299 ? -12.771 -10.968 64.229  1 19.258 ? 291  TRP A C   1 
ATOM   2148 O  O   . TRP A 1 299 ? -13.701 -10.992 65      1 18.762 ? 291  TRP A O   1 
ATOM   2149 C  CB  . TRP A 1 299 ? -11.343 -9.02   64.85   1 18.262 ? 291  TRP A CB  1 
ATOM   2150 C  CG  . TRP A 1 299 ? -10.833 -7.637  64.58   1 19.606 ? 291  TRP A CG  1 
ATOM   2151 C  CD1 . TRP A 1 299 ? -11.492 -6.481  64.879  1 21.517 ? 291  TRP A CD1 1 
ATOM   2152 C  CD2 . TRP A 1 299 ? -9.55   -7.248  64.029  1 16.605 ? 291  TRP A CD2 1 
ATOM   2153 N  NE1 . TRP A 1 299 ? -10.697 -5.406  64.567  1 21.155 ? 291  TRP A NE1 1 
ATOM   2154 C  CE2 . TRP A 1 299 ? -9.512  -5.832  64.042  1 15.855 ? 291  TRP A CE2 1 
ATOM   2155 C  CE3 . TRP A 1 299 ? -8.446  -7.933  63.529  1 13.545 ? 291  TRP A CE3 1 
ATOM   2156 C  CZ2 . TRP A 1 299 ? -8.42   -5.095  63.561  1 18.807 ? 291  TRP A CZ2 1 
ATOM   2157 C  CZ3 . TRP A 1 299 ? -7.348  -7.217  63.091  1 17.872 ? 291  TRP A CZ3 1 
ATOM   2158 C  CH2 . TRP A 1 299 ? -7.307  -5.816  63.143  1 19.084 ? 291  TRP A CH2 1 
ATOM   2159 N  N   . ILE A 1 300 ? -12.152 -12.066 63.749  1 17.281 ? 292  ILE A N   1 
ATOM   2160 C  CA  . ILE A 1 300 ? -12.467 -13.433 64.17   1 15.138 ? 292  ILE A CA  1 
ATOM   2161 C  C   . ILE A 1 300 ? -11.257 -13.985 64.906  1 16.9   ? 292  ILE A C   1 
ATOM   2162 O  O   . ILE A 1 300 ? -10.154 -14.113 64.348  1 13.761 ? 292  ILE A O   1 
ATOM   2163 C  CB  . ILE A 1 300 ? -12.825 -14.313 62.947  1 17.869 ? 292  ILE A CB  1 
ATOM   2164 C  CG1 . ILE A 1 300 ? -14.017 -13.735 62.194  1 18.172 ? 292  ILE A CG1 1 
ATOM   2165 C  CG2 . ILE A 1 300 ? -13.018 -15.79  63.348  1 16.233 ? 292  ILE A CG2 1 
ATOM   2166 C  CD1 . ILE A 1 300 ? -14.287 -14.343 60.838  1 20.884 ? 292  ILE A CD1 1 
ATOM   2167 N  N   . THR A 1 301 ? -11.42  -14.231 66.23   1 17.2   ? 293  THR A N   1 
ATOM   2168 C  CA  . THR A 1 301 ? -10.339 -14.84  66.978  1 15.314 ? 293  THR A CA  1 
ATOM   2169 C  C   . THR A 1 301 ? -10.523 -16.351 66.867  1 16.268 ? 293  THR A C   1 
ATOM   2170 O  O   . THR A 1 301 ? -11.621 -16.866 67.127  1 16.692 ? 293  THR A O   1 
ATOM   2171 C  CB  . THR A 1 301 ? -10.248 -14.386 68.454  1 14.379 ? 293  THR A CB  1 
ATOM   2172 O  OG1 . THR A 1 301 ? -11.563 -14.481 68.965  1 14.864 ? 293  THR A OG1 1 
ATOM   2173 C  CG2 . THR A 1 301 ? -9.857  -12.925 68.574  1 15.705 ? 293  THR A CG2 1 
ATOM   2174 N  N   . ILE A 1 302 ? -9.454  -17.043 66.428  1 14.548 ? 294  ILE A N   1 
ATOM   2175 C  CA  . ILE A 1 302 ? -9.378  -18.495 66.31   1 13.44  ? 294  ILE A CA  1 
ATOM   2176 C  C   . ILE A 1 302 ? -8.278  -18.934 67.262  1 15.281 ? 294  ILE A C   1 
ATOM   2177 O  O   . ILE A 1 302 ? -7.079  -18.773 67.006  1 13.514 ? 294  ILE A O   1 
ATOM   2178 C  CB  . ILE A 1 302 ? -9.102  -18.985 64.881  1 15.282 ? 294  ILE A CB  1 
ATOM   2179 C  CG1 . ILE A 1 302 ? -10.025 -18.314 63.864  1 14.982 ? 294  ILE A CG1 1 
ATOM   2180 C  CG2 . ILE A 1 302 ? -9.217  -20.511 64.801  1 14.922 ? 294  ILE A CG2 1 
ATOM   2181 C  CD1 . ILE A 1 302 ? -9.771  -18.676 62.4    1 17.196 ? 294  ILE A CD1 1 
ATOM   2182 N  N   . PRO A 1 303 ? -8.646  -19.513 68.42   1 18.253 ? 295  PRO A N   1 
ATOM   2183 C  CA  . PRO A 1 303 ? -7.623  -20.112 69.293  1 17.842 ? 295  PRO A CA  1 
ATOM   2184 C  C   . PRO A 1 303 ? -6.757  -21.125 68.534  1 18.212 ? 295  PRO A C   1 
ATOM   2185 O  O   . PRO A 1 303 ? -7.295  -21.996 67.851  1 20.741 ? 295  PRO A O   1 
ATOM   2186 C  CB  . PRO A 1 303 ? -8.454  -20.777 70.408  1 17     ? 295  PRO A CB  1 
ATOM   2187 C  CG  . PRO A 1 303 ? -9.784  -20.06  70.387  1 18.597 ? 295  PRO A CG  1 
ATOM   2188 C  CD  . PRO A 1 303 ? -10.034 -19.654 68.918  1 18.25  ? 295  PRO A CD  1 
ATOM   2189 N  N   . ARG A 1 304 ? -5.422  -21.034 68.634  1 17.178 ? 296  ARG A N   1 
ATOM   2190 C  CA  . ARG A 1 304 ? -4.55   -21.924 67.876  1 21.693 ? 296  ARG A CA  1 
ATOM   2191 C  C   . ARG A 1 304 ? -4.764  -23.384 68.307  1 20.537 ? 296  ARG A C   1 
ATOM   2192 O  O   . ARG A 1 304 ? -4.769  -23.701 69.508  1 18.88  ? 296  ARG A O   1 
ATOM   2193 C  CB  . ARG A 1 304 ? -3.058  -21.587 67.859  1 18.649 ? 296  ARG A CB  1 
ATOM   2194 C  CG  . ARG A 1 304 ? -2.943  -20.255 67.11   1 18.181 ? 296  ARG A CG  1 
ATOM   2195 C  CD  . ARG A 1 304 ? -1.55   -19.624 67.117  1 17.47  ? 296  ARG A CD  1 
ATOM   2196 N  NE  . ARG A 1 304 ? -0.608  -20.554 66.488  1 16.739 ? 296  ARG A NE  1 
ATOM   2197 C  CZ  . ARG A 1 304 ? 0.68    -20.361 66.429  1 16.18  ? 296  ARG A CZ  1 
ATOM   2198 N  NH1 . ARG A 1 304 ? 1.142   -19.236 66.954  1 18.29  ? 296  ARG A NH1 1 
ATOM   2199 N  NH2 . ARG A 1 304 ? 1.467   -21.323 65.91   1 17.787 ? 296  ARG A NH2 1 
ATOM   2200 N  N   . GLY A 1 305 ? -4.984  -24.237 67.313  1 17.793 ? 297  GLY A N   1 
ATOM   2201 C  CA  . GLY A 1 305 ? -5.287  -25.656 67.538  1 18.089 ? 297  GLY A CA  1 
ATOM   2202 C  C   . GLY A 1 305 ? -6.68   -25.901 68.155  1 20.931 ? 297  GLY A C   1 
ATOM   2203 O  O   . GLY A 1 305 ? -6.888  -26.91  68.84   1 21.228 ? 297  GLY A O   1 
ATOM   2204 N  N   . ALA A 1 306 ? -7.617  -24.951 67.964  1 21.311 ? 298  ALA A N   1 
ATOM   2205 C  CA  . ALA A 1 306 ? -8.992  -25.1   68.414  1 23.733 ? 298  ALA A CA  1 
ATOM   2206 C  C   . ALA A 1 306 ? -9.602  -26.441 67.996  1 25.138 ? 298  ALA A C   1 
ATOM   2207 O  O   . ALA A 1 306 ? -9.524  -26.885 66.841  1 23.337 ? 298  ALA A O   1 
ATOM   2208 C  CB  . ALA A 1 306 ? -9.844  -23.939 67.922  1 31.155 ? 298  ALA A CB  1 
ATOM   2209 N  N   . LYS A 1 307 ? -10.308 -27.015 68.967  1 25.306 ? 299  LYS A N   1 
ATOM   2210 C  CA  . LYS A 1 307 ? -10.984 -28.286 68.813  1 30.971 ? 299  LYS A CA  1 
ATOM   2211 C  C   . LYS A 1 307 ? -12.402 -28.098 68.271  1 24.596 ? 299  LYS A C   1 
ATOM   2212 O  O   . LYS A 1 307 ? -12.903 -29.008 67.617  1 27.987 ? 299  LYS A O   1 
ATOM   2213 C  CB  . LYS A 1 307 ? -10.84  -29.097 70.115  1 34.752 ? 299  LYS A CB  1 
ATOM   2214 C  CG  . LYS A 1 307 ? -9.387  -29.566 70.296  1 39.827 ? 299  LYS A CG  1 
ATOM   2215 C  CD  . LYS A 1 307 ? -9.014  -30.801 69.469  1 46.511 ? 299  LYS A CD  1 
ATOM   2216 C  CE  . LYS A 1 307 ? -7.671  -30.835 68.762  1 49.366 ? 299  LYS A CE  1 
ATOM   2217 N  NZ  . LYS A 1 307 ? -7.621  -31.956 67.813  1 49.748 ? 299  LYS A NZ  1 
ATOM   2218 N  N   . SER A 1 308 ? -12.989 -26.913 68.485  1 22.081 ? 300  SER A N   1 
ATOM   2219 C  CA  . SER A 1 308 ? -14.339 -26.632 68.016  1 22.566 ? 300  SER A CA  1 
ATOM   2220 C  C   . SER A 1 308 ? -14.467 -25.226 67.438  1 20.761 ? 300  SER A C   1 
ATOM   2221 O  O   . SER A 1 308 ? -13.902 -24.301 68.003  1 20.653 ? 300  SER A O   1 
ATOM   2222 C  CB  . SER A 1 308 ? -15.314 -26.792 69.178  1 22.214 ? 300  SER A CB  1 
ATOM   2223 O  OG  . SER A 1 308 ? -16.622 -26.548 68.706  1 26.84  ? 300  SER A OG  1 
ATOM   2224 N  N   . LYS A 1 309 ? -15.315 -25.07  66.381  1 24.524 ? 301  LYS A N   1 
ATOM   2225 C  CA  . LYS A 1 309 ? -15.745 -23.74  65.924  1 21.874 ? 301  LYS A CA  1 
ATOM   2226 C  C   . LYS A 1 309 ? -16.432 -22.97  67.057  1 23.472 ? 301  LYS A C   1 
ATOM   2227 O  O   . LYS A 1 309 ? -16.495 -21.747 67.027  1 17.881 ? 301  LYS A O   1 
ATOM   2228 C  CB  . LYS A 1 309 ? -16.579 -23.852 64.652  1 20.387 ? 301  LYS A CB  1 
ATOM   2229 C  CG  . LYS A 1 309 ? -17.985 -24.429 64.842  1 23.928 ? 301  LYS A CG  1 
ATOM   2230 C  CD  . LYS A 1 309 ? -18.753 -24.508 63.533  1 25.636 ? 301  LYS A CD  1 
ATOM   2231 C  CE  . LYS A 1 309 ? -20.229 -24.517 63.797  1 33.71  ? 301  LYS A CE  1 
ATOM   2232 N  NZ  . LYS A 1 309 ? -20.803 -24.718 62.467  1 44.054 ? 301  LYS A NZ  1 
ATOM   2233 N  N   . ASP A 1 310 ? -16.908 -23.691 68.084  1 24.551 ? 302  ASP A N   1 
ATOM   2234 C  CA  . ASP A 1 310 ? -17.437 -23.069 69.307  1 26.891 ? 302  ASP A CA  1 
ATOM   2235 C  C   . ASP A 1 310 ? -16.438 -22.14  70.009  1 22.236 ? 302  ASP A C   1 
ATOM   2236 O  O   . ASP A 1 310 ? -16.826 -21.29  70.797  1 22.086 ? 302  ASP A O   1 
ATOM   2237 C  CB  . ASP A 1 310 ? -17.91  -24.088 70.332  1 28.764 ? 302  ASP A CB  1 
ATOM   2238 C  CG  . ASP A 1 310 ? -19.12  -24.944 69.962  1 31.136 ? 302  ASP A CG  1 
ATOM   2239 O  OD1 . ASP A 1 310 ? -19.674 -24.816 68.836  1 31.27  ? 302  ASP A OD1 1 
ATOM   2240 O  OD2 . ASP A 1 310 ? -19.469 -25.782 70.795  1 30.088 ? 302  ASP A OD2 1 
ATOM   2241 N  N   . GLU A 1 311 ? -15.143 -22.311 69.778  1 20.21  ? 303  GLU A N   1 
ATOM   2242 C  CA  . GLU A 1 311 ? -14.104 -21.565 70.481  1 18.275 ? 303  GLU A CA  1 
ATOM   2243 C  C   . GLU A 1 311 ? -13.811 -20.214 69.802  1 21.029 ? 303  GLU A C   1 
ATOM   2244 O  O   . GLU A 1 311 ? -13.184 -19.346 70.409  1 17.336 ? 303  GLU A O   1 
ATOM   2245 C  CB  . GLU A 1 311 ? -12.804 -22.357 70.469  1 18.982 ? 303  GLU A CB  1 
ATOM   2246 C  CG  . GLU A 1 311 ? -12.862 -23.667 71.248  1 24.494 ? 303  GLU A CG  1 
ATOM   2247 C  CD  . GLU A 1 311 ? -11.505 -24.351 71.321  1 22.328 ? 303  GLU A CD  1 
ATOM   2248 O  OE1 . GLU A 1 311 ? -10.447 -23.77  71.63   1 22.214 ? 303  GLU A OE1 1 
ATOM   2249 O  OE2 . GLU A 1 311 ? -11.565 -25.535 71.033  1 22.111 ? 303  GLU A OE2 1 
ATOM   2250 N  N   . VAL A 1 312 ? -14.268 -20.055 68.536  1 19.494 ? 304  VAL A N   1 
ATOM   2251 C  CA  . VAL A 1 312 ? -14.053 -18.86  67.738  1 17.55  ? 304  VAL A CA  1 
ATOM   2252 C  C   . VAL A 1 312 ? -15.01  -17.751 68.215  1 18.708 ? 304  VAL A C   1 
ATOM   2253 O  O   . VAL A 1 312 ? -16.185 -18.012 68.518  1 21.646 ? 304  VAL A O   1 
ATOM   2254 C  CB  . VAL A 1 312 ? -14.314 -19.332 66.286  1 18.237 ? 304  VAL A CB  1 
ATOM   2255 C  CG1 . VAL A 1 312 ? -14.337 -18.195 65.268  1 18.765 ? 304  VAL A CG1 1 
ATOM   2256 C  CG2 . VAL A 1 312 ? -13.297 -20.38  65.835  1 20.37  ? 304  VAL A CG2 1 
ATOM   2257 N  N   . LYS A 1 313 ? -14.534 -16.489 68.212  1 13.832 ? 305  LYS A N   1 
ATOM   2258 C  CA  . LYS A 1 313 ? -15.34  -15.327 68.584  1 16.055 ? 305  LYS A CA  1 
ATOM   2259 C  C   . LYS A 1 313 ? -15.283 -14.252 67.511  1 17.754 ? 305  LYS A C   1 
ATOM   2260 O  O   . LYS A 1 313 ? -14.266 -14.154 66.837  1 19.365 ? 305  LYS A O   1 
ATOM   2261 C  CB  . LYS A 1 313 ? -14.956 -14.836 69.995  1 14.545 ? 305  LYS A CB  1 
ATOM   2262 C  CG  . LYS A 1 313 ? -15.015 -15.875 71.077  1 17.328 ? 305  LYS A CG  1 
ATOM   2263 C  CD  . LYS A 1 313 ? -14.908 -15.191 72.446  1 21.374 ? 305  LYS A CD  1 
ATOM   2264 C  CE  . LYS A 1 313 ? -15.121 -16.072 73.661  1 29.701 ? 305  LYS A CE  1 
ATOM   2265 N  NZ  . LYS A 1 313 ? -16.317 -16.889 73.474  1 36.251 ? 305  LYS A NZ  1 
ATOM   2266 N  N   . TYR A 1 314 ? -16.397 -13.49  67.326  1 19.497 ? 306  TYR A N   1 
ATOM   2267 C  CA  . TYR A 1 314 ? -16.422 -12.275 66.518  1 20.992 ? 306  TYR A CA  1 
ATOM   2268 C  C   . TYR A 1 314 ? -16.402 -11.031 67.408  1 19.981 ? 306  TYR A C   1 
ATOM   2269 O  O   . TYR A 1 314 ? -17.082 -10.968 68.442  1 22.361 ? 306  TYR A O   1 
ATOM   2270 C  CB  . TYR A 1 314 ? -17.673 -12.218 65.625  1 20.554 ? 306  TYR A CB  1 
ATOM   2271 C  CG  . TYR A 1 314 ? -18.034 -13.472 64.828  1 20.572 ? 306  TYR A CG  1 
ATOM   2272 C  CD1 . TYR A 1 314 ? -17.045 -14.323 64.311  1 19.021 ? 306  TYR A CD1 1 
ATOM   2273 C  CD2 . TYR A 1 314 ? -19.359 -13.747 64.494  1 20.313 ? 306  TYR A CD2 1 
ATOM   2274 C  CE1 . TYR A 1 314 ? -17.378 -15.463 63.595  1 19.316 ? 306  TYR A CE1 1 
ATOM   2275 C  CE2 . TYR A 1 314 ? -19.709 -14.849 63.721  1 17.718 ? 306  TYR A CE2 1 
ATOM   2276 C  CZ  . TYR A 1 314 ? -18.715 -15.713 63.288  1 19.241 ? 306  TYR A CZ  1 
ATOM   2277 O  OH  . TYR A 1 314 ? -19.003 -16.821 62.542  1 20.671 ? 306  TYR A OH  1 
ATOM   2278 N  N   . TRP A 1 315 ? -15.553 -10.072 67.03   1 18.957 ? 307  TRP A N   1 
ATOM   2279 C  CA  . TRP A 1 315 ? -15.388 -8.791  67.681  1 18.607 ? 307  TRP A CA  1 
ATOM   2280 C  C   . TRP A 1 315 ? -15.66  -7.708  66.64   1 24.11  ? 307  TRP A C   1 
ATOM   2281 O  O   . TRP A 1 315 ? -15.322 -7.865  65.464  1 21.245 ? 307  TRP A O   1 
ATOM   2282 C  CB  . TRP A 1 315 ? -13.955 -8.692  68.226  1 15.592 ? 307  TRP A CB  1 
ATOM   2283 C  CG  . TRP A 1 315 ? -13.549 -9.893  69.032  1 14.931 ? 307  TRP A CG  1 
ATOM   2284 C  CD1 . TRP A 1 315 ? -13.218 -11.149 68.59   1 17.333 ? 307  TRP A CD1 1 
ATOM   2285 C  CD2 . TRP A 1 315 ? -13.481 -9.93   70.478  1 14.789 ? 307  TRP A CD2 1 
ATOM   2286 N  NE1 . TRP A 1 315 ? -12.946 -11.953 69.672  1 18.222 ? 307  TRP A NE1 1 
ATOM   2287 C  CE2 . TRP A 1 315 ? -13.102 -11.24  70.832  1 15.309 ? 307  TRP A CE2 1 
ATOM   2288 C  CE3 . TRP A 1 315 ? -13.721 -8.98   71.482  1 14.433 ? 307  TRP A CE3 1 
ATOM   2289 C  CZ2 . TRP A 1 315 ? -12.971 -11.641 72.178  1 16.608 ? 307  TRP A CZ2 1 
ATOM   2290 C  CZ3 . TRP A 1 315 ? -13.619 -9.379  72.821  1 15.728 ? 307  TRP A CZ3 1 
ATOM   2291 C  CH2 . TRP A 1 315 ? -13.289 -10.704 73.143  1 17.169 ? 307  TRP A CH2 1 
ATOM   2292 N  N   . HIS A 1 316 ? -16.226 -6.577  67.069  1 19.56  ? 308  HIS A N   1 
ATOM   2293 C  CA  . HIS A 1 316 ? -16.57  -5.568  66.076  1 19.371 ? 308  HIS A CA  1 
ATOM   2294 C  C   . HIS A 1 316 ? -16.126 -4.176  66.544  1 21.769 ? 308  HIS A C   1 
ATOM   2295 O  O   . HIS A 1 316 ? -16.058 -3.887  67.758  1 18.991 ? 308  HIS A O   1 
ATOM   2296 C  CB  . HIS A 1 316 ? -18.035 -5.762  65.676  1 21.318 ? 308  HIS A CB  1 
ATOM   2297 C  CG  . HIS A 1 316 ? -18.979 -5.233  66.707  1 21.569 ? 308  HIS A CG  1 
ATOM   2298 N  ND1 . HIS A 1 316 ? -19.343 -5.973  67.805  1 20.675 ? 308  HIS A ND1 1 
ATOM   2299 C  CD2 . HIS A 1 316 ? -19.486 -4.012  66.897  1 22.403 ? 308  HIS A CD2 1 
ATOM   2300 C  CE1 . HIS A 1 316 ? -20.081 -5.234  68.609  1 21.505 ? 308  HIS A CE1 1 
ATOM   2301 N  NE2 . HIS A 1 316 ? -20.195 -4.048  68.071  1 20.884 ? 308  HIS A NE2 1 
ATOM   2302 N  N   . TRP A 1 317 ? -15.874 -3.292  65.577  1 16.62  ? 309  TRP A N   1 
ATOM   2303 C  CA  . TRP A 1 317 ? -15.634 -1.903  65.923  1 19.972 ? 309  TRP A CA  1 
ATOM   2304 C  C   . TRP A 1 317 ? -16.647 -1.015  65.223  1 18.655 ? 309  TRP A C   1 
ATOM   2305 O  O   . TRP A 1 317 ? -17.801 -1.039  65.629  1 20.806 ? 309  TRP A O   1 
ATOM   2306 C  CB  . TRP A 1 317 ? -14.152 -1.485  65.771  1 20.245 ? 309  TRP A CB  1 
ATOM   2307 C  CG  . TRP A 1 317 ? -13.931 -0.032  66.096  1 19.096 ? 309  TRP A CG  1 
ATOM   2308 C  CD1 . TRP A 1 317 ? -14.046 0.549   67.334  1 18.075 ? 309  TRP A CD1 1 
ATOM   2309 C  CD2 . TRP A 1 317 ? -13.597 1.018   65.166  1 18.365 ? 309  TRP A CD2 1 
ATOM   2310 N  NE1 . TRP A 1 317 ? -13.826 1.896   67.223  1 16.787 ? 309  TRP A NE1 1 
ATOM   2311 C  CE2 . TRP A 1 317 ? -13.557 2.215   65.908  1 19.503 ? 309  TRP A CE2 1 
ATOM   2312 C  CE3 . TRP A 1 317 ? -13.369 1.072   63.773  1 17.992 ? 309  TRP A CE3 1 
ATOM   2313 C  CZ2 . TRP A 1 317 ? -13.254 3.448   65.31   1 21.85  ? 309  TRP A CZ2 1 
ATOM   2314 C  CZ3 . TRP A 1 317 ? -13.11  2.293   63.181  1 20.19  ? 309  TRP A CZ3 1 
ATOM   2315 C  CH2 . TRP A 1 317 ? -13.027 3.469   63.939  1 21.746 ? 309  TRP A CH2 1 
ATOM   2316 N  N   . LYS A 1 318 ? -16.235 -0.277  64.16   1 17.664 ? 310  LYS A N   1 
ATOM   2317 C  CA  . LYS A 1 318 ? -17.14  0.548   63.386  1 18.022 ? 310  LYS A CA  1 
ATOM   2318 C  C   . LYS A 1 318 ? -16.68  0.447   61.933  1 16.567 ? 310  LYS A C   1 
ATOM   2319 O  O   . LYS A 1 318 ? -15.637 -0.152  61.669  1 16.67  ? 310  LYS A O   1 
ATOM   2320 C  CB  . LYS A 1 318 ? -16.988 1.981   63.912  1 20.425 ? 310  LYS A CB  1 
ATOM   2321 C  CG  . LYS A 1 318 ? -17.3   2.211   65.386  1 27.191 ? 310  LYS A CG  1 
ATOM   2322 C  CD  . LYS A 1 318 ? -17.076 3.663   65.797  1 27.593 ? 310  LYS A CD  1 
ATOM   2323 C  CE  . LYS A 1 318 ? -17.192 3.762   67.288  1 33.715 ? 310  LYS A CE  1 
ATOM   2324 N  NZ  . LYS A 1 318 ? -16.48  4.924   67.855  1 39.074 ? 310  LYS A NZ  1 
ATOM   2325 N  N   . ASN A 1 319 ? -17.361 1.096   61.01   1 16.407 ? 311  ASN A N   1 
ATOM   2326 C  CA  . ASN A 1 319 ? -16.983 0.925   59.596  1 15.798 ? 311  ASN A CA  1 
ATOM   2327 C  C   . ASN A 1 319 ? -15.625 1.564   59.276  1 15.998 ? 311  ASN A C   1 
ATOM   2328 O  O   . ASN A 1 319 ? -15.241 2.582   59.856  1 17.857 ? 311  ASN A O   1 
ATOM   2329 C  CB  . ASN A 1 319 ? -18.004 1.602   58.7    1 17.713 ? 311  ASN A CB  1 
ATOM   2330 C  CG  . ASN A 1 319 ? -17.741 1.418   57.222  1 15.313 ? 311  ASN A CG  1 
ATOM   2331 O  OD1 . ASN A 1 319 ? -17.44  2.379   56.501  1 16.563 ? 311  ASN A OD1 1 
ATOM   2332 N  ND2 . ASN A 1 319 ? -17.788 0.175   56.784  1 14.723 ? 311  ASN A ND2 1 
ATOM   2333 N  N   . GLY A 1 320 ? -14.898 0.968   58.32   1 17.69  ? 312  GLY A N   1 
ATOM   2334 C  CA  . GLY A 1 320 ? -13.629 1.498   57.804  1 16.454 ? 312  GLY A CA  1 
ATOM   2335 C  C   . GLY A 1 320 ? -12.81  0.333   57.228  1 19.034 ? 312  GLY A C   1 
ATOM   2336 O  O   . GLY A 1 320 ? -13.296 -0.79   57.237  1 18.18  ? 312  GLY A O   1 
ATOM   2337 N  N   . MET A 1 321 ? -11.57  0.59    56.777  1 15.449 ? 313  MET A N   1 
ATOM   2338 C  CA  . MET A 1 321 ? -10.854 -0.423  56.003  1 13.799 ? 313  MET A CA  1 
ATOM   2339 C  C   . MET A 1 321 ? -9.44   -0.501  56.544  1 14.234 ? 313  MET A C   1 
ATOM   2340 O  O   . MET A 1 321 ? -8.575  0.332   56.219  1 15.034 ? 313  MET A O   1 
ATOM   2341 C  CB  . MET A 1 321 ? -11.018 -0.128  54.493  1 12.016 ? 313  MET A CB  1 
ATOM   2342 C  CG  . MET A 1 321 ? -10.439 -1.193  53.64   1 12.122 ? 313  MET A CG  1 
ATOM   2343 S  SD  . MET A 1 321 ? -10.902 -0.759  51.951  1 13.774 ? 313  MET A SD  1 
ATOM   2344 C  CE  . MET A 1 321 ? -9.61   -1.818  51.282  1 14.31  ? 313  MET A CE  1 
ATOM   2345 N  N   . PRO A 1 322 ? -9.17   -1.41   57.511  1 15.154 ? 314  PRO A N   1 
ATOM   2346 C  CA  . PRO A 1 322 ? -7.806  -1.657  57.923  1 15.829 ? 314  PRO A CA  1 
ATOM   2347 C  C   . PRO A 1 322 ? -7.146  -2.627  56.95   1 14.681 ? 314  PRO A C   1 
ATOM   2348 O  O   . PRO A 1 322 ? -7.605  -3.772  56.909  1 12.954 ? 314  PRO A O   1 
ATOM   2349 C  CB  . PRO A 1 322 ? -8.006  -2.364  59.296  1 15.631 ? 314  PRO A CB  1 
ATOM   2350 C  CG  . PRO A 1 322 ? -9.333  -3.051  59.25   1 15.116 ? 314  PRO A CG  1 
ATOM   2351 C  CD  . PRO A 1 322 ? -10.114 -2.375  58.118  1 17.252 ? 314  PRO A CD  1 
ATOM   2352 N  N   . ILE A 1 323 ? -6.164  -2.138  56.15   1 17.322 ? 315  ILE A N   1 
ATOM   2353 C  CA  . ILE A 1 323 ? -5.762  -2.862  54.955  1 14.327 ? 315  ILE A CA  1 
ATOM   2354 C  C   . ILE A 1 323 ? -4.862  -4.062  55.28   1 16.184 ? 315  ILE A C   1 
ATOM   2355 O  O   . ILE A 1 323 ? -5.184  -5.217  54.906  1 16.202 ? 315  ILE A O   1 
ATOM   2356 C  CB  . ILE A 1 323 ? -5.302  -1.96   53.781  1 16.171 ? 315  ILE A CB  1 
ATOM   2357 C  CG1 . ILE A 1 323 ? -6.298  -0.873  53.453  1 15.555 ? 315  ILE A CG1 1 
ATOM   2358 C  CG2 . ILE A 1 323 ? -5.032  -2.815  52.523  1 15.427 ? 315  ILE A CG2 1 
ATOM   2359 C  CD1 . ILE A 1 323 ? -5.741  0.318   52.676  1 21.383 ? 315  ILE A CD1 1 
ATOM   2360 N  N   . HIS A 1 324 ? -3.755  -3.794  56.005  1 13.526 ? 316  HIS A N   1 
ATOM   2361 C  CA  . HIS A 1 324 ? -2.725  -4.752  56.324  1 15.11  ? 316  HIS A CA  1 
ATOM   2362 C  C   . HIS A 1 324 ? -2.336  -4.549  57.787  1 16.267 ? 316  HIS A C   1 
ATOM   2363 O  O   . HIS A 1 324 ? -2.304  -3.412  58.275  1 18.195 ? 316  HIS A O   1 
ATOM   2364 C  CB  . HIS A 1 324 ? -1.534  -4.534  55.439  1 13.955 ? 316  HIS A CB  1 
ATOM   2365 C  CG  . HIS A 1 324 ? -1.754  -5.063  54.044  1 11.522 ? 316  HIS A CG  1 
ATOM   2366 N  ND1 . HIS A 1 324 ? -1.642  -4.179  53.011  1 11.875 ? 316  HIS A ND1 1 
ATOM   2367 C  CD2 . HIS A 1 324 ? -1.952  -6.26   53.527  1 13.317 ? 316  HIS A CD2 1 
ATOM   2368 C  CE1 . HIS A 1 324 ? -1.718  -4.82   51.847  1 11.04  ? 316  HIS A CE1 1 
ATOM   2369 N  NE2 . HIS A 1 324 ? -2.016  -6.068  52.167  1 12.776 ? 316  HIS A NE2 1 
ATOM   2370 N  N   . THR A 1 325 ? -2.136  -5.685  58.441  1 12.575 ? 317  THR A N   1 
ATOM   2371 C  CA  . THR A 1 325 ? -1.553  -5.664  59.774  1 14.414 ? 317  THR A CA  1 
ATOM   2372 C  C   . THR A 1 325 ? -0.03   -5.572  59.641  1 15.727 ? 317  THR A C   1 
ATOM   2373 O  O   . THR A 1 325 ? 0.584   -6.037  58.666  1 15.544 ? 317  THR A O   1 
ATOM   2374 C  CB  . THR A 1 325 ? -1.971  -6.918  60.535  1 11.871 ? 317  THR A CB  1 
ATOM   2375 O  OG1 . THR A 1 325 ? -1.54   -8.107  59.847  1 15.989 ? 317  THR A OG1 1 
ATOM   2376 C  CG2 . THR A 1 325 ? -3.452  -6.963  60.776  1 16.093 ? 317  THR A CG2 1 
ATOM   2377 N  N   . ALA A 1 326 ? 0.582   -4.991  60.656  1 14.021 ? 318  ALA A N   1 
ATOM   2378 C  CA  . ALA A 1 326 ? 2.018   -5.11   60.81   1 16.176 ? 318  ALA A CA  1 
ATOM   2379 C  C   . ALA A 1 326 ? 2.274   -6.492  61.402  1 15.573 ? 318  ALA A C   1 
ATOM   2380 O  O   . ALA A 1 326 ? 2.76    -7.422  60.726  1 14.868 ? 318  ALA A O   1 
ATOM   2381 C  CB  . ALA A 1 326 ? 2.46    -3.97   61.706  1 15.477 ? 318  ALA A CB  1 
ATOM   2382 N  N   . SER A 1 327 ? 1.993   -6.635  62.708  1 18.338 ? 319  SER A N   1 
ATOM   2383 C  CA  . SER A 1 327 ? 1.743   -7.935  63.298  1 17.209 ? 319  SER A CA  1 
ATOM   2384 C  C   . SER A 1 327 ? 0.845   -7.824  64.554  1 15.247 ? 319  SER A C   1 
ATOM   2385 O  O   . SER A 1 327 ? 0.206   -6.774  64.753  1 14.519 ? 319  SER A O   1 
ATOM   2386 C  CB  . SER A 1 327 ? 3.056   -8.653  63.558  1 18.214 ? 319  SER A CB  1 
ATOM   2387 O  OG  . SER A 1 327 ? 2.86    -10.033 63.79   1 15.753 ? 319  SER A OG  1 
ATOM   2388 N  N   . GLY A 1 328 ? 0.761   -8.95   65.281  1 14.4   ? 320  GLY A N   1 
ATOM   2389 C  CA  . GLY A 1 328 ? 0.081   -8.982  66.57   1 15.339 ? 320  GLY A CA  1 
ATOM   2390 C  C   . GLY A 1 328 ? 0.88    -9.703  67.624  1 15.569 ? 320  GLY A C   1 
ATOM   2391 O  O   . GLY A 1 328 ? 1.894   -10.341 67.366  1 19.101 ? 320  GLY A O   1 
ATOM   2392 N  N   . PHE A 1 329 ? 0.394   -9.598  68.866  1 18.421 ? 321  PHE A N   1 
ATOM   2393 C  CA  . PHE A 1 329 ? 0.99    -10.369 69.932  1 18.446 ? 321  PHE A CA  1 
ATOM   2394 C  C   . PHE A 1 329 ? 0.024   -10.375 71.102  1 16.952 ? 321  PHE A C   1 
ATOM   2395 O  O   . PHE A 1 329 ? -0.983  -9.692  71.027  1 17.091 ? 321  PHE A O   1 
ATOM   2396 C  CB  . PHE A 1 329 ? 2.348   -9.788  70.328  1 17.189 ? 321  PHE A CB  1 
ATOM   2397 C  CG  . PHE A 1 329 ? 2.386   -8.411  70.978  1 19.277 ? 321  PHE A CG  1 
ATOM   2398 C  CD1 . PHE A 1 329 ? 2.357   -7.242  70.212  1 18.236 ? 321  PHE A CD1 1 
ATOM   2399 C  CD2 . PHE A 1 329 ? 2.41    -8.321  72.389  1 16.841 ? 321  PHE A CD2 1 
ATOM   2400 C  CE1 . PHE A 1 329 ? 2.377   -5.992  70.804  1 23.111 ? 321  PHE A CE1 1 
ATOM   2401 C  CE2 . PHE A 1 329 ? 2.419   -7.074  72.989  1 16.379 ? 321  PHE A CE2 1 
ATOM   2402 C  CZ  . PHE A 1 329 ? 2.387   -5.905  72.21   1 23.797 ? 321  PHE A CZ  1 
ATOM   2403 N  N   . GLU A 1 330 ? 0.408   -11.103 72.157  1 19.174 ? 322  GLU A N   1 
ATOM   2404 C  CA  . GLU A 1 330 ? -0.34   -11.097 73.403  1 19.128 ? 322  GLU A CA  1 
ATOM   2405 C  C   . GLU A 1 330 ? 0.463   -10.365 74.447  1 17.541 ? 322  GLU A C   1 
ATOM   2406 O  O   . GLU A 1 330 ? 1.623   -10.725 74.67   1 18.946 ? 322  GLU A O   1 
ATOM   2407 C  CB  . GLU A 1 330 ? -0.756  -12.511 73.82   1 19.354 ? 322  GLU A CB  1 
ATOM   2408 C  CG  . GLU A 1 330 ? -1.936  -13.039 72.999  1 18.446 ? 322  GLU A CG  1 
ATOM   2409 C  CD  . GLU A 1 330 ? -1.976  -14.535 73.07   1 18.598 ? 322  GLU A CD  1 
ATOM   2410 O  OE1 . GLU A 1 330 ? -1.961  -15.083 74.202  1 20.601 ? 322  GLU A OE1 1 
ATOM   2411 O  OE2 . GLU A 1 330 ? -1.967  -15.171 71.987  1 15.946 ? 322  GLU A OE2 1 
ATOM   2412 N  N   . ASP A 1 331 ? -0.135  -9.337  75.055  1 18.721 ? 323  ASP A N   1 
ATOM   2413 C  CA  . ASP A 1 331 ? 0.575   -8.614  76.12   1 20.338 ? 323  ASP A CA  1 
ATOM   2414 C  C   . ASP A 1 331 ? 0.577   -9.453  77.398  1 22.227 ? 323  ASP A C   1 
ATOM   2415 O  O   . ASP A 1 331 ? -0.002  -10.541 77.423  1 19.403 ? 323  ASP A O   1 
ATOM   2416 C  CB  . ASP A 1 331 ? 0.009   -7.203  76.309  1 18.343 ? 323  ASP A CB  1 
ATOM   2417 C  CG  . ASP A 1 331 ? -1.34   -7.089  77.013  1 20.144 ? 323  ASP A CG  1 
ATOM   2418 O  OD1 . ASP A 1 331 ? -1.911  -8.122  77.51   1 24.268 ? 323  ASP A OD1 1 
ATOM   2419 O  OD2 . ASP A 1 331 ? -1.867  -5.99   76.957  1 22.777 ? 323  ASP A OD2 1 
ATOM   2420 N  N   . GLU A 1 332 ? 1.263   -8.927  78.449  1 20.236 ? 324  GLU A N   1 
ATOM   2421 C  CA  . GLU A 1 332 ? 1.415   -9.581  79.761  1 28.2   ? 324  GLU A CA  1 
ATOM   2422 C  C   . GLU A 1 332 ? 0.118   -10.135 80.381  1 25.464 ? 324  GLU A C   1 
ATOM   2423 O  O   . GLU A 1 332 ? 0.17    -11.144 81.121  1 26.779 ? 324  GLU A O   1 
ATOM   2424 C  CB  . GLU A 1 332 ? 2.236   -8.722  80.726  1 24.834 ? 324  GLU A CB  1 
ATOM   2425 C  CG  . GLU A 1 332 ? 3.663   -8.468  80.209  1 28.748 ? 324  GLU A CG  1 
ATOM   2426 C  CD  . GLU A 1 332 ? 3.921   -7.194  79.382  1 33.509 ? 324  GLU A CD  1 
ATOM   2427 O  OE1 . GLU A 1 332 ? 2.975   -6.568  78.762  1 33.756 ? 324  GLU A OE1 1 
ATOM   2428 O  OE2 . GLU A 1 332 ? 5.121   -6.772  79.368  1 31.902 ? 324  GLU A OE2 1 
ATOM   2429 N  N   . GLN A 1 333 ? -1.019  -9.491  80.083  1 23.454 ? 325  GLN A N   1 
ATOM   2430 C  CA  . GLN A 1 333 ? -2.352  -9.784  80.608  1 23.426 ? 325  GLN A CA  1 
ATOM   2431 C  C   . GLN A 1 333 ? -3.174  -10.63  79.633  1 24.738 ? 325  GLN A C   1 
ATOM   2432 O  O   . GLN A 1 333 ? -4.349  -10.876 79.878  1 24.57  ? 325  GLN A O   1 
ATOM   2433 C  CB  . GLN A 1 333 ? -3.196  -8.504  80.638  1 24.973 ? 325  GLN A CB  1 
ATOM   2434 C  CG  . GLN A 1 333 ? -2.711  -7.343  81.5    1 28.249 ? 325  GLN A CG  1 
ATOM   2435 C  CD  . GLN A 1 333 ? -1.369  -6.688  81.177  1 24.145 ? 325  GLN A CD  1 
ATOM   2436 O  OE1 . GLN A 1 333 ? -1.212  -5.896  80.227  1 24.838 ? 325  GLN A OE1 1 
ATOM   2437 N  NE2 . GLN A 1 333 ? -0.405  -6.911  82.057  1 19.777 ? 325  GLN A NE2 1 
ATOM   2438 N  N   . GLY A 1 334 ? -2.576  -11.007 78.505  1 25.325 ? 326  GLY A N   1 
ATOM   2439 C  CA  . GLY A 1 334 ? -3.218  -11.891 77.53   1 25.838 ? 326  GLY A CA  1 
ATOM   2440 C  C   . GLY A 1 334 ? -4.001  -11.133 76.464  1 24.252 ? 326  GLY A C   1 
ATOM   2441 O  O   . GLY A 1 334 ? -4.69   -11.757 75.658  1 18.739 ? 326  GLY A O   1 
ATOM   2442 N  N   . ARG A 1 335 ? -3.875  -9.8    76.423  1 25.973 ? 327  ARG A N   1 
ATOM   2443 C  CA  . ARG A 1 335 ? -4.68   -9.031  75.486  1 17.262 ? 327  ARG A CA  1 
ATOM   2444 C  C   . ARG A 1 335 ? -3.998  -9.138  74.111  1 19.155 ? 327  ARG A C   1 
ATOM   2445 O  O   . ARG A 1 335 ? -2.768  -9.118  74.005  1 19.263 ? 327  ARG A O   1 
ATOM   2446 C  CB  . ARG A 1 335 ? -4.921  -7.546  75.804  1 15.92  ? 327  ARG A CB  1 
ATOM   2447 C  CG  . ARG A 1 335 ? -5.265  -7.318  77.297  1 20.328 ? 327  ARG A CG  1 
ATOM   2448 C  CD  . ARG A 1 335 ? -5.667  -5.89   77.733  1 22.577 ? 327  ARG A CD  1 
ATOM   2449 N  NE  . ARG A 1 335 ? -4.474  -5.024  77.813  1 20.404 ? 327  ARG A NE  1 
ATOM   2450 C  CZ  . ARG A 1 335 ? -4.428  -3.675  77.755  1 19.399 ? 327  ARG A CZ  1 
ATOM   2451 N  NH1 . ARG A 1 335 ? -5.518  -2.93   77.763  1 21.356 ? 327  ARG A NH1 1 
ATOM   2452 N  NH2 . ARG A 1 335 ? -3.236  -3.074  77.707  1 22.126 ? 327  ARG A NH2 1 
ATOM   2453 N  N   . ILE A 1 336 ? -4.828  -9.308  73.084  1 21.6   ? 328  ILE A N   1 
ATOM   2454 C  CA  . ILE A 1 336 ? -4.406  -9.279  71.68   1 18.494 ? 328  ILE A CA  1 
ATOM   2455 C  C   . ILE A 1 336 ? -4.186  -7.838  71.245  1 17.211 ? 328  ILE A C   1 
ATOM   2456 O  O   . ILE A 1 336 ? -5.115  -7.022  71.292  1 18.716 ? 328  ILE A O   1 
ATOM   2457 C  CB  . ILE A 1 336 ? -5.448  -9.963  70.796  1 16.669 ? 328  ILE A CB  1 
ATOM   2458 C  CG1 . ILE A 1 336 ? -5.657  -11.439 71.241  1 17.67  ? 328  ILE A CG1 1 
ATOM   2459 C  CG2 . ILE A 1 336 ? -4.993  -9.856  69.335  1 16.724 ? 328  ILE A CG2 1 
ATOM   2460 C  CD1 . ILE A 1 336 ? -6.914  -12.119 70.717  1 17.744 ? 328  ILE A CD1 1 
ATOM   2461 N  N   . ILE A 1 337 ? -2.938  -7.517  70.865  1 17.594 ? 329  ILE A N   1 
ATOM   2462 C  CA  . ILE A 1 337 ? -2.631  -6.169  70.367  1 15.195 ? 329  ILE A CA  1 
ATOM   2463 C  C   . ILE A 1 337 ? -2.234  -6.359  68.906  1 14.908 ? 329  ILE A C   1 
ATOM   2464 O  O   . ILE A 1 337 ? -1.364  -7.164  68.634  1 15.45  ? 329  ILE A O   1 
ATOM   2465 C  CB  . ILE A 1 337 ? -1.47   -5.583  71.186  1 21.481 ? 329  ILE A CB  1 
ATOM   2466 C  CG1 . ILE A 1 337 ? -1.735  -5.59   72.758  1 20.582 ? 329  ILE A CG1 1 
ATOM   2467 C  CG2 . ILE A 1 337 ? -1.029  -4.187  70.71   1 20.393 ? 329  ILE A CG2 1 
ATOM   2468 C  CD1 . ILE A 1 337 ? -3.03   -4.966  73.209  1 22.644 ? 329  ILE A CD1 1 
ATOM   2469 N  N   . ILE A 1 338 ? -2.875  -5.632  68.031  1 17.492 ? 330  ILE A N   1 
ATOM   2470 C  CA  . ILE A 1 338 ? -2.557  -5.663  66.597  1 15.691 ? 330  ILE A CA  1 
ATOM   2471 C  C   . ILE A 1 338 ? -2.366  -4.216  66.123  1 15.056 ? 330  ILE A C   1 
ATOM   2472 O  O   . ILE A 1 338 ? -3.275  -3.388  66.362  1 17.093 ? 330  ILE A O   1 
ATOM   2473 C  CB  . ILE A 1 338 ? -3.737  -6.321  65.882  1 16.414 ? 330  ILE A CB  1 
ATOM   2474 C  CG1 . ILE A 1 338 ? -3.996  -7.745  66.412  1 21.402 ? 330  ILE A CG1 1 
ATOM   2475 C  CG2 . ILE A 1 338 ? -3.509  -6.3    64.349  1 13.88  ? 330  ILE A CG2 1 
ATOM   2476 C  CD1 . ILE A 1 338 ? -5.32   -8.361  65.992  1 20.158 ? 330  ILE A CD1 1 
ATOM   2477 N  N   . ASP A 1 339 ? -1.352  -3.933  65.271  1 13.97  ? 331  ASP A N   1 
ATOM   2478 C  CA  . ASP A 1 339 ? -1.326  -2.672  64.567  1 15.21  ? 331  ASP A CA  1 
ATOM   2479 C  C   . ASP A 1 339 ? -1.65   -2.908  63.084  1 15.628 ? 331  ASP A C   1 
ATOM   2480 O  O   . ASP A 1 339 ? -1.257  -3.955  62.527  1 16.474 ? 331  ASP A O   1 
ATOM   2481 C  CB  . ASP A 1 339 ? 0.034   -1.975  64.667  1 15.019 ? 331  ASP A CB  1 
ATOM   2482 C  CG  . ASP A 1 339 ? 0.476   -1.45   66.023  1 17.742 ? 331  ASP A CG  1 
ATOM   2483 O  OD1 . ASP A 1 339 ? -0.229  -1.792  67.002  1 20.255 ? 331  ASP A OD1 1 
ATOM   2484 O  OD2 . ASP A 1 339 ? 1.574   -0.755  66.093  1 18.524 ? 331  ASP A OD2 1 
ATOM   2485 N  N   . SER A 1 340 ? -2.325  -1.912  62.501  1 15.363 ? 332  SER A N   1 
ATOM   2486 C  CA  . SER A 1 340 ? -2.707  -1.981  61.107  1 16.478 ? 332  SER A CA  1 
ATOM   2487 C  C   . SER A 1 340 ? -2.784  -0.593  60.521  1 16.026 ? 332  SER A C   1 
ATOM   2488 O  O   . SER A 1 340 ? -2.959  0.4     61.242  1 17.79  ? 332  SER A O   1 
ATOM   2489 C  CB  . SER A 1 340 ? -4.079  -2.681  60.976  1 17.698 ? 332  SER A CB  1 
ATOM   2490 O  OG  . SER A 1 340 ? -5.165  -1.817  61.305  1 17.3   ? 332  SER A OG  1 
ATOM   2491 N  N   . SER A 1 341 ? -2.836  -0.556  59.178  1 16.137 ? 333  SER A N   1 
ATOM   2492 C  CA  . SER A 1 341 ? -3.286  0.678   58.611  1 15.198 ? 333  SER A CA  1 
ATOM   2493 C  C   . SER A 1 341 ? -4.815  0.775   58.795  1 17.849 ? 333  SER A C   1 
ATOM   2494 O  O   . SER A 1 341 ? -5.486  -0.198  59.119  1 21.516 ? 333  SER A O   1 
ATOM   2495 C  CB  . SER A 1 341 ? -2.86   0.743   57.165  1 16.973 ? 333  SER A CB  1 
ATOM   2496 O  OG  . SER A 1 341 ? -3.434  -0.39   56.524  1 18.396 ? 333  SER A OG  1 
ATOM   2497 N  N   . LEU A 1 342 ? -5.34   1.996   58.739  1 15.351 ? 334  LEU A N   1 
ATOM   2498 C  CA  . LEU A 1 342 ? -6.755  2.307   58.826  1 15.467 ? 334  LEU A CA  1 
ATOM   2499 C  C   . LEU A 1 342 ? -7.019  3.462   57.893  1 18.823 ? 334  LEU A C   1 
ATOM   2500 O  O   . LEU A 1 342 ? -6.474  4.564   58.109  1 17.404 ? 334  LEU A O   1 
ATOM   2501 C  CB  . LEU A 1 342 ? -7.222  2.704   60.24   1 16.646 ? 334  LEU A CB  1 
ATOM   2502 C  CG  . LEU A 1 342 ? -8.712  3.053   60.412  1 17.33  ? 334  LEU A CG  1 
ATOM   2503 C  CD1 . LEU A 1 342 ? -9.535  1.865   59.925  1 16.922 ? 334  LEU A CD1 1 
ATOM   2504 C  CD2 . LEU A 1 342 ? -8.893  3.093   61.959  1 15.893 ? 334  LEU A CD2 1 
ATOM   2505 N  N   . VAL A 1 343 ? -7.863  3.142   56.895  1 19.035 ? 335  VAL A N   1 
ATOM   2506 C  CA  . VAL A 1 343 ? -8.457  4.054   55.964  1 17.331 ? 335  VAL A CA  1 
ATOM   2507 C  C   . VAL A 1 343 ? -9.926  4.19    56.326  1 17.299 ? 335  VAL A C   1 
ATOM   2508 O  O   . VAL A 1 343 ? -10.68  3.2     56.371  1 14.85  ? 335  VAL A O   1 
ATOM   2509 C  CB  . VAL A 1 343 ? -8.238  3.627   54.495  1 17.007 ? 335  VAL A CB  1 
ATOM   2510 C  CG1 . VAL A 1 343 ? -8.884  4.626   53.547  1 17.447 ? 335  VAL A CG1 1 
ATOM   2511 C  CG2 . VAL A 1 343 ? -6.743  3.589   54.177  1 15.838 ? 335  VAL A CG2 1 
ATOM   2512 N  N   . HIS A 1 344 ? -10.335 5.451   56.51   1 19.63  ? 336  HIS A N   1 
ATOM   2513 C  CA  . HIS A 1 344 ? -11.645 5.761   57.072  1 18.786 ? 336  HIS A CA  1 
ATOM   2514 C  C   . HIS A 1 344 ? -12.767 5.765   56.023  1 21.99  ? 336  HIS A C   1 
ATOM   2515 O  O   . HIS A 1 344 ? -13.452 6.765   55.866  1 21.211 ? 336  HIS A O   1 
ATOM   2516 C  CB  . HIS A 1 344 ? -11.541 7.022   57.932  1 18.785 ? 336  HIS A CB  1 
ATOM   2517 C  CG  . HIS A 1 344 ? -10.808 6.841   59.214  1 18.849 ? 336  HIS A CG  1 
ATOM   2518 N  ND1 . HIS A 1 344 ? -11.381 6.4     60.385  1 24.766 ? 336  HIS A ND1 1 
ATOM   2519 C  CD2 . HIS A 1 344 ? -9.499  7.018   59.511  1 20.119 ? 336  HIS A CD2 1 
ATOM   2520 C  CE1 . HIS A 1 344 ? -10.468 6.372   61.363  1 23.396 ? 336  HIS A CE1 1 
ATOM   2521 N  NE2 . HIS A 1 344 ? -9.322  6.773   60.829  1 22.994 ? 336  HIS A NE2 1 
ATOM   2522 N  N   . GLY A 1 345 ? -12.994 4.631   55.354  1 16.451 ? 337  GLY A N   1 
ATOM   2523 C  CA  . GLY A 1 345 ? -13.785 4.551   54.138  1 18.448 ? 337  GLY A CA  1 
ATOM   2524 C  C   . GLY A 1 345 ? -13.141 3.633   53.107  1 16.704 ? 337  GLY A C   1 
ATOM   2525 O  O   . GLY A 1 345 ? -12.317 2.808   53.47   1 13.957 ? 337  GLY A O   1 
ATOM   2526 N  N   . ASN A 1 346 ? -13.495 3.821   51.831  1 16.128 ? 338  ASN A N   1 
ATOM   2527 C  CA  . ASN A 1 346 ? -13.194 2.79    50.858  1 17.544 ? 338  ASN A CA  1 
ATOM   2528 C  C   . ASN A 1 346 ? -11.872 3.058   50.148  1 19.832 ? 338  ASN A C   1 
ATOM   2529 O  O   . ASN A 1 346 ? -11.826 3.949   49.288  1 21.518 ? 338  ASN A O   1 
ATOM   2530 C  CB  . ASN A 1 346 ? -14.372 2.546   49.925  1 17.16  ? 338  ASN A CB  1 
ATOM   2531 C  CG  . ASN A 1 346 ? -14.156 1.374   48.983  1 18.381 ? 338  ASN A CG  1 
ATOM   2532 O  OD1 . ASN A 1 346 ? -13.128 0.658   49.058  1 18.223 ? 338  ASN A OD1 1 
ATOM   2533 N  ND2 . ASN A 1 346 ? -15.066 1.201   48.038  1 15.135 ? 338  ASN A ND2 1 
ATOM   2534 N  N   . ALA A 1 347 ? -10.846 2.244   50.442  1 16.809 ? 339  ALA A N   1 
ATOM   2535 C  CA  . ALA A 1 347 ? -9.538  2.386   49.793  1 18.238 ? 339  ALA A CA  1 
ATOM   2536 C  C   . ALA A 1 347 ? -9.493  1.675   48.434  1 17.308 ? 339  ALA A C   1 
ATOM   2537 O  O   . ALA A 1 347 ? -8.503  1.888   47.687  1 18.988 ? 339  ALA A O   1 
ATOM   2538 C  CB  . ALA A 1 347 ? -8.384  1.919   50.66   1 17.526 ? 339  ALA A CB  1 
ATOM   2539 N  N   . PHE A 1 348 ? -10.513 0.847   48.128  1 14.727 ? 340  PHE A N   1 
ATOM   2540 C  CA  . PHE A 1 348 ? -10.708 0.302   46.769  1 13.868 ? 340  PHE A CA  1 
ATOM   2541 C  C   . PHE A 1 348 ? -12.003 0.855   46.16   1 14.356 ? 340  PHE A C   1 
ATOM   2542 O  O   . PHE A 1 348 ? -12.997 0.129   46.028  1 13.855 ? 340  PHE A O   1 
ATOM   2543 C  CB  . PHE A 1 348 ? -10.863 -1.235  46.888  1 14.936 ? 340  PHE A CB  1 
ATOM   2544 C  CG  . PHE A 1 348 ? -9.611  -2.088  47.078  1 18.197 ? 340  PHE A CG  1 
ATOM   2545 C  CD1 . PHE A 1 348 ? -8.35   -1.505  47.199  1 13.209 ? 340  PHE A CD1 1 
ATOM   2546 C  CD2 . PHE A 1 348 ? -9.714  -3.469  47.184  1 16.814 ? 340  PHE A CD2 1 
ATOM   2547 C  CE1 . PHE A 1 348 ? -7.207  -2.29   47.32   1 15.555 ? 340  PHE A CE1 1 
ATOM   2548 C  CE2 . PHE A 1 348 ? -8.555  -4.243  47.31   1 13.177 ? 340  PHE A CE2 1 
ATOM   2549 C  CZ  . PHE A 1 348 ? -7.33   -3.675  47.356  1 12.439 ? 340  PHE A CZ  1 
ATOM   2550 N  N   . PRO A 1 349 ? -12.046 2.146   45.749  1 17.794 ? 341  PRO A N   1 
ATOM   2551 C  CA  . PRO A 1 349 ? -13.256 2.744   45.246  1 17.153 ? 341  PRO A CA  1 
ATOM   2552 C  C   . PRO A 1 349 ? -13.748 2.128   43.943  1 16.251 ? 341  PRO A C   1 
ATOM   2553 O  O   . PRO A 1 349 ? -14.916 2.297   43.654  1 18.216 ? 341  PRO A O   1 
ATOM   2554 C  CB  . PRO A 1 349 ? -12.836 4.213   45.011  1 21.262 ? 341  PRO A CB  1 
ATOM   2555 C  CG  . PRO A 1 349 ? -11.349 4.149   44.708  1 18.69  ? 341  PRO A CG  1 
ATOM   2556 C  CD  . PRO A 1 349 ? -10.944 3.131   45.82   1 15.444 ? 341  PRO A CD  1 
ATOM   2557 N  N   . PHE A 1 350 ? -12.907 1.285   43.3    1 16.629 ? 342  PHE A N   1 
ATOM   2558 C  CA  . PHE A 1 350 ? -13.274 0.599   42.051  1 19.517 ? 342  PHE A CA  1 
ATOM   2559 C  C   . PHE A 1 350 ? -14.224 -0.576  42.369  1 16.28  ? 342  PHE A C   1 
ATOM   2560 O  O   . PHE A 1 350 ? -14.807 -1.116  41.434  1 15.434 ? 342  PHE A O   1 
ATOM   2561 C  CB  . PHE A 1 350 ? -12.041 0.184   41.219  1 18.83  ? 342  PHE A CB  1 
ATOM   2562 C  CG  . PHE A 1 350 ? -10.958 -0.487  42.072  1 18.266 ? 342  PHE A CG  1 
ATOM   2563 C  CD1 . PHE A 1 350 ? -10.995 -1.862  42.368  1 20.151 ? 342  PHE A CD1 1 
ATOM   2564 C  CD2 . PHE A 1 350 ? -9.908  0.275   42.584  1 20.281 ? 342  PHE A CD2 1 
ATOM   2565 C  CE1 . PHE A 1 350 ? -10.055 -2.407  43.23   1 16.414 ? 342  PHE A CE1 1 
ATOM   2566 C  CE2 . PHE A 1 350 ? -8.965  -0.266  43.422  1 20.697 ? 342  PHE A CE2 1 
ATOM   2567 C  CZ  . PHE A 1 350 ? -9.039  -1.623  43.721  1 20.919 ? 342  PHE A CZ  1 
ATOM   2568 N  N   . PHE A 1 351 ? -14.357 -0.947  43.666  1 13.934 ? 343  PHE A N   1 
ATOM   2569 C  CA  . PHE A 1 351 ? -15.439 -1.821  44.157  1 13.928 ? 343  PHE A CA  1 
ATOM   2570 C  C   . PHE A 1 351 ? -16.449 -1.003  44.973  1 14.187 ? 343  PHE A C   1 
ATOM   2571 O  O   . PHE A 1 351 ? -16.463 -1.063  46.203  1 19.599 ? 343  PHE A O   1 
ATOM   2572 C  CB  . PHE A 1 351 ? -15.009 -3.072  44.919  1 12.064 ? 343  PHE A CB  1 
ATOM   2573 C  CG  . PHE A 1 351 ? -13.935 -3.928  44.241  1 13.349 ? 343  PHE A CG  1 
ATOM   2574 C  CD1 . PHE A 1 351 ? -13.938 -4.096  42.841  1 13.49  ? 343  PHE A CD1 1 
ATOM   2575 C  CD2 . PHE A 1 351 ? -12.957 -4.624  45.009  1 13.5   ? 343  PHE A CD2 1 
ATOM   2576 C  CE1 . PHE A 1 351 ? -13.01  -4.931  42.203  1 14.934 ? 343  PHE A CE1 1 
ATOM   2577 C  CE2 . PHE A 1 351 ? -12.013 -5.439  44.371  1 15.635 ? 343  PHE A CE2 1 
ATOM   2578 C  CZ  . PHE A 1 351 ? -12.022 -5.556  42.957  1 14.375 ? 343  PHE A CZ  1 
ATOM   2579 N  N   . PRO A 1 352 ? -17.303 -0.171  44.341  1 14.669 ? 344  PRO A N   1 
ATOM   2580 C  CA  . PRO A 1 352 ? -18.219 0.663   45.114  1 15.32  ? 344  PRO A CA  1 
ATOM   2581 C  C   . PRO A 1 352 ? -19.334 -0.12   45.839  1 19.521 ? 344  PRO A C   1 
ATOM   2582 O  O   . PRO A 1 352 ? -19.581 -1.316  45.549  1 17.4   ? 344  PRO A O   1 
ATOM   2583 C  CB  . PRO A 1 352 ? -18.801 1.615   44.031  1 17.846 ? 344  PRO A CB  1 
ATOM   2584 C  CG  . PRO A 1 352 ? -18.755 0.757   42.787  1 14.603 ? 344  PRO A CG  1 
ATOM   2585 C  CD  . PRO A 1 352 ? -17.499 -0.034  42.863  1 14.113 ? 344  PRO A CD  1 
ATOM   2586 N  N   . PRO A 1 353 ? -20.127 0.551   46.731  1 20.852 ? 345  PRO A N   1 
ATOM   2587 C  CA  . PRO A 1 353 ? -21.365 -0.029  47.253  1 20.624 ? 345  PRO A CA  1 
ATOM   2588 C  C   . PRO A 1 353 ? -22.358 -0.382  46.178  1 16.239 ? 345  PRO A C   1 
ATOM   2589 O  O   . PRO A 1 353 ? -22.208 0.068   45.034  1 17.69  ? 345  PRO A O   1 
ATOM   2590 C  CB  . PRO A 1 353 ? -21.93  1.076   48.154  1 23.017 ? 345  PRO A CB  1 
ATOM   2591 C  CG  . PRO A 1 353 ? -20.673 1.918   48.502  1 23.369 ? 345  PRO A CG  1 
ATOM   2592 C  CD  . PRO A 1 353 ? -19.879 1.914   47.265  1 21.503 ? 345  PRO A CD  1 
ATOM   2593 N  N   . ASP A 1 354 ? -23.275 -1.317  46.51   1 18.248 ? 346  ASP A N   1 
ATOM   2594 C  CA  . ASP A 1 354 ? -24.427 -1.628  45.679  1 24.559 ? 346  ASP A CA  1 
ATOM   2595 C  C   . ASP A 1 354 ? -25.432 -0.481  45.56   1 23.603 ? 346  ASP A C   1 
ATOM   2596 O  O   . ASP A 1 354 ? -25.96  -0.23   44.47   1 25.98  ? 346  ASP A O   1 
ATOM   2597 C  CB  . ASP A 1 354 ? -25.342 -2.695  46.305  1 28.37  ? 346  ASP A CB  1 
ATOM   2598 C  CG  . ASP A 1 354 ? -25.21  -4.147  45.899  1 36.211 ? 346  ASP A CG  1 
ATOM   2599 O  OD1 . ASP A 1 354 ? -25.072 -4.417  44.661  1 29.271 ? 346  ASP A OD1 1 
ATOM   2600 O  OD2 . ASP A 1 354 ? -25.328 -4.991  46.847  1 38.373 ? 346  ASP A OD2 1 
ATOM   2601 N  N   . SER A 1 355 ? -25.816 0.112   46.696  1 23.873 ? 347  SER A N   1 
ATOM   2602 C  CA  . SER A 1 355 ? -26.997 0.983   46.667  1 22.036 ? 347  SER A CA  1 
ATOM   2603 C  C   . SER A 1 355 ? -26.63  2.367   46.157  1 25.883 ? 347  SER A C   1 
ATOM   2604 O  O   . SER A 1 355 ? -25.489 2.814   46.335  1 19.545 ? 347  SER A O   1 
ATOM   2605 C  CB  . SER A 1 355 ? -27.687 1.038   47.986  1 23.624 ? 347  SER A CB  1 
ATOM   2606 O  OG  . SER A 1 355 ? -26.974 1.844   48.898  1 23.311 ? 347  SER A OG  1 
ATOM   2607 N  N   . ASP A 1 356 ? -27.617 3.056   45.558  1 26.74  ? 348  ASP A N   1 
ATOM   2608 C  CA  . ASP A 1 356 ? -27.395 4.411   45.059  1 27.405 ? 348  ASP A CA  1 
ATOM   2609 C  C   . ASP A 1 356 ? -26.96  5.313   46.203  1 24.86  ? 348  ASP A C   1 
ATOM   2610 O  O   . ASP A 1 356 ? -26.023 6.119   46.052  1 20.029 ? 348  ASP A O   1 
ATOM   2611 C  CB  . ASP A 1 356 ? -28.618 4.977   44.364  1 32.187 ? 348  ASP A CB  1 
ATOM   2612 C  CG  . ASP A 1 356 ? -28.832 4.523   42.928  1 41.377 ? 348  ASP A CG  1 
ATOM   2613 O  OD1 . ASP A 1 356 ? -27.853 4.067   42.257  1 46.473 ? 348  ASP A OD1 1 
ATOM   2614 O  OD2 . ASP A 1 356 ? -29.99  4.594   42.496  1 43.066 ? 348  ASP A OD2 1 
ATOM   2615 N  N   . GLU A 1 357 ? -27.618 5.111   47.344  1 24.391 ? 349  GLU A N   1 
ATOM   2616 C  CA  . GLU A 1 357 ? -27.39  5.847   48.574  1 20.904 ? 349  GLU A CA  1 
ATOM   2617 C  C   . GLU A 1 357 ? -25.919 5.775   49.001  1 19.298 ? 349  GLU A C   1 
ATOM   2618 O  O   . GLU A 1 357 ? -25.284 6.808   49.26   1 14.507 ? 349  GLU A O   1 
ATOM   2619 C  CB  . GLU A 1 357 ? -28.45  5.472   49.611  1 24.872 ? 349  GLU A CB  1 
ATOM   2620 C  CG  . GLU A 1 357 ? -28.032 5.851   51.031  1 31.278 ? 349  GLU A CG  1 
ATOM   2621 C  CD  . GLU A 1 357 ? -28.84  5.731   52.291  1 37.804 ? 349  GLU A CD  1 
ATOM   2622 O  OE1 . GLU A 1 357 ? -29.844 4.975   52.403  1 39.688 ? 349  GLU A OE1 1 
ATOM   2623 O  OE2 . GLU A 1 357 ? -28.398 6.496   53.185  1 37.15  ? 349  GLU A OE2 1 
ATOM   2624 N  N   . GLN A 1 358 ? -25.382 4.548   49.123  1 15.638 ? 350  GLN A N   1 
ATOM   2625 C  CA  . GLN A 1 358 ? -23.992 4.378   49.532  1 16.732 ? 350  GLN A CA  1 
ATOM   2626 C  C   . GLN A 1 358 ? -23.028 4.809   48.446  1 15.867 ? 350  GLN A C   1 
ATOM   2627 O  O   . GLN A 1 358 ? -21.943 5.248   48.786  1 15.566 ? 350  GLN A O   1 
ATOM   2628 C  CB  . GLN A 1 358 ? -23.809 2.932   49.934  1 18.537 ? 350  GLN A CB  1 
ATOM   2629 C  CG  . GLN A 1 358 ? -24.499 2.567   51.244  1 19.429 ? 350  GLN A CG  1 
ATOM   2630 C  CD  . GLN A 1 358 ? -23.845 1.386   51.915  1 18.725 ? 350  GLN A CD  1 
ATOM   2631 O  OE1 . GLN A 1 358 ? -22.642 1.158   51.726  1 16.742 ? 350  GLN A OE1 1 
ATOM   2632 N  NE2 . GLN A 1 358 ? -24.604 0.685   52.764  1 17.418 ? 350  GLN A NE2 1 
ATOM   2633 N  N   . LYS A 1 359 ? -23.42  4.671   47.161  1 13.422 ? 351  LYS A N   1 
ATOM   2634 C  CA  . LYS A 1 359 ? -22.621 5.176   46.061  1 14.583 ? 351  LYS A CA  1 
ATOM   2635 C  C   . LYS A 1 359 ? -22.384 6.668   46.207  1 17.651 ? 351  LYS A C   1 
ATOM   2636 O  O   . LYS A 1 359 ? -21.258 7.141   46.044  1 17.539 ? 351  LYS A O   1 
ATOM   2637 C  CB  . LYS A 1 359 ? -23.119 4.929   44.631  1 15.928 ? 351  LYS A CB  1 
ATOM   2638 C  CG  . LYS A 1 359 ? -22.749 3.483   44.283  1 23.006 ? 351  LYS A CG  1 
ATOM   2639 C  CD  . LYS A 1 359 ? -22.959 3.386   42.776  1 27.272 ? 351  LYS A CD  1 
ATOM   2640 C  CE  . LYS A 1 359 ? -22.611 2.039   42.334  1 32.401 ? 351  LYS A CE  1 
ATOM   2641 N  NZ  . LYS A 1 359 ? -23.8   1.18    42.46   1 44.407 ? 351  LYS A NZ  1 
ATOM   2642 N  N   . LYS A 1 360 ? -23.445 7.386   46.568  1 16.254 ? 352  LYS A N   1 
ATOM   2643 C  CA  . LYS A 1 360 ? -23.307 8.817   46.663  1 16.491 ? 352  LYS A CA  1 
ATOM   2644 C  C   . LYS A 1 360 ? -22.404 9.163   47.856  1 15.241 ? 352  LYS A C   1 
ATOM   2645 O  O   . LYS A 1 360 ? -21.646 10.119  47.772  1 15.931 ? 352  LYS A O   1 
ATOM   2646 C  CB  . LYS A 1 360 ? -24.738 9.379   46.791  1 16.2   ? 352  LYS A CB  1 
ATOM   2647 C  CG  . LYS A 1 360 ? -25.517 9.472   45.5    1 19.659 ? 352  LYS A CG  1 
ATOM   2648 C  CD  . LYS A 1 360 ? -26.895 10.158  45.673  1 17.197 ? 352  LYS A CD  1 
ATOM   2649 C  CE  . LYS A 1 360 ? -27.815 9.823   44.519  1 17.592 ? 352  LYS A CE  1 
ATOM   2650 N  NZ  . LYS A 1 360 ? -27.288 10.188  43.187  1 18.672 ? 352  LYS A NZ  1 
ATOM   2651 N  N   . LYS A 1 361 ? -22.479 8.379   48.944  1 15.265 ? 353  LYS A N   1 
ATOM   2652 C  CA  . LYS A 1 361 ? -21.632 8.61    50.111  1 15.385 ? 353  LYS A CA  1 
ATOM   2653 C  C   . LYS A 1 361 ? -20.151 8.405   49.788  1 14.665 ? 353  LYS A C   1 
ATOM   2654 O  O   . LYS A 1 361 ? -19.31  9.218   50.162  1 15.903 ? 353  LYS A O   1 
ATOM   2655 C  CB  . LYS A 1 361 ? -22.093 7.691   51.237  1 12.99  ? 353  LYS A CB  1 
ATOM   2656 C  CG  . LYS A 1 361 ? -21.304 8.04    52.501  1 18.342 ? 353  LYS A CG  1 
ATOM   2657 C  CD  . LYS A 1 361 ? -21.887 7.346   53.705  1 18.497 ? 353  LYS A CD  1 
ATOM   2658 C  CE  . LYS A 1 361 ? -20.931 7.645   54.863  1 22.841 ? 353  LYS A CE  1 
ATOM   2659 N  NZ  . LYS A 1 361 ? -21.085 9.008   55.365  1 28.237 ? 353  LYS A NZ  1 
ATOM   2660 N  N   . GLN A 1 362 ? -19.831 7.339   49.049  1 18.262 ? 354  GLN A N   1 
ATOM   2661 C  CA  . GLN A 1 362 ? -18.456 7.159   48.57   1 15.833 ? 354  GLN A CA  1 
ATOM   2662 C  C   . GLN A 1 362 ? -17.985 8.389   47.79   1 16.178 ? 354  GLN A C   1 
ATOM   2663 O  O   . GLN A 1 362 ? -16.894 8.864   48.046  1 16.387 ? 354  GLN A O   1 
ATOM   2664 C  CB  . GLN A 1 362 ? -18.265 5.856   47.78   1 18.068 ? 354  GLN A CB  1 
ATOM   2665 C  CG  . GLN A 1 362 ? -16.799 5.56    47.449  1 16.732 ? 354  GLN A CG  1 
ATOM   2666 C  CD  . GLN A 1 362 ? -16.641 4.319   46.581  1 18.652 ? 354  GLN A CD  1 
ATOM   2667 O  OE1 . GLN A 1 362 ? -16.887 3.213   47.061  1 20.64  ? 354  GLN A OE1 1 
ATOM   2668 N  NE2 . GLN A 1 362 ? -16.344 4.498   45.29   1 16.543 ? 354  GLN A NE2 1 
ATOM   2669 N  N   . GLU A 1 363 ? -18.812 8.902   46.849  1 17.373 ? 355  GLU A N   1 
ATOM   2670 C  CA  . GLU A 1 363 ? -18.401 10.045  46.041  1 19.995 ? 355  GLU A CA  1 
ATOM   2671 C  C   . GLU A 1 363 ? -18.196 11.254  46.965  1 19.97  ? 355  GLU A C   1 
ATOM   2672 O  O   . GLU A 1 363 ? -17.145 11.919  46.948  1 16.461 ? 355  GLU A O   1 
ATOM   2673 C  CB  . GLU A 1 363 ? -19.329 10.326  44.861  1 18.744 ? 355  GLU A CB  1 
ATOM   2674 C  CG  . GLU A 1 363 ? -18.767 11.392  43.927  1 19.797 ? 355  GLU A CG  1 
ATOM   2675 C  CD  . GLU A 1 363 ? -19.49  11.478  42.569  1 19.843 ? 355  GLU A CD  1 
ATOM   2676 O  OE1 . GLU A 1 363 ? -20.597 10.919  42.44   1 24.854 ? 355  GLU A OE1 1 
ATOM   2677 O  OE2 . GLU A 1 363 ? -19.02  12.165  41.652  1 24.404 ? 355  GLU A OE2 1 
ATOM   2678 N  N   . ALA A 1 364 ? -19.161 11.408  47.879  1 20.55  ? 356  ALA A N   1 
ATOM   2679 C  CA  . ALA A 1 364 ? -19.168 12.52   48.817  1 20.501 ? 356  ALA A CA  1 
ATOM   2680 C  C   . ALA A 1 364 ? -17.9   12.512  49.664  1 21.184 ? 356  ALA A C   1 
ATOM   2681 O  O   . ALA A 1 364 ? -17.26  13.556  49.797  1 20.824 ? 356  ALA A O   1 
ATOM   2682 C  CB  . ALA A 1 364 ? -20.423 12.526  49.652  1 22.464 ? 356  ALA A CB  1 
ATOM   2683 N  N   . ASP A 1 365 ? -17.564 11.346  50.197  1 16.777 ? 357  ASP A N   1 
ATOM   2684 C  CA  . ASP A 1 365 ? -16.379 11.2    51.04   1 24.805 ? 357  ASP A CA  1 
ATOM   2685 C  C   . ASP A 1 365 ? -15.041 11.482  50.363  1 22.477 ? 357  ASP A C   1 
ATOM   2686 O  O   . ASP A 1 365 ? -14.122 11.77   51.09   1 24.416 ? 357  ASP A O   1 
ATOM   2687 C  CB  . ASP A 1 365 ? -16.323 9.874   51.771  1 19.7   ? 357  ASP A CB  1 
ATOM   2688 C  CG  . ASP A 1 365 ? -17.328 9.71    52.897  1 25.151 ? 357  ASP A CG  1 
ATOM   2689 O  OD1 . ASP A 1 365 ? -18.014 10.711  53.248  1 23.682 ? 357  ASP A OD1 1 
ATOM   2690 O  OD2 . ASP A 1 365 ? -17.5   8.559   53.33   1 29.12  ? 357  ASP A OD2 1 
ATOM   2691 N  N   . GLY A 1 366 ? -14.914 11.358  49.034  1 20.635 ? 358  GLY A N   1 
ATOM   2692 C  CA  . GLY A 1 366 ? -13.634 11.498  48.342  1 24.046 ? 358  GLY A CA  1 
ATOM   2693 C  C   . GLY A 1 366 ? -12.539 10.591  48.942  1 27.698 ? 358  GLY A C   1 
ATOM   2694 O  O   . GLY A 1 366 ? -12.827 9.472   49.343  1 27.159 ? 358  GLY A O   1 
ATOM   2695 N  N   . THR A 1 367 ? -11.312 11.122  49.105  1 26.074 ? 359  THR A N   1 
ATOM   2696 C  CA  . THR A 1 367 ? -10.155 10.39   49.618  1 23.928 ? 359  THR A CA  1 
ATOM   2697 C  C   . THR A 1 367 ? -10.308 10.297  51.13   1 21.957 ? 359  THR A C   1 
ATOM   2698 O  O   . THR A 1 367 ? -10.334 11.346  51.746  1 21.883 ? 359  THR A O   1 
ATOM   2699 C  CB  . THR A 1 367 ? -8.898  11.194  49.263  1 24.414 ? 359  THR A CB  1 
ATOM   2700 O  OG1 . THR A 1 367 ? -8.788  11.13   47.85   1 23.749 ? 359  THR A OG1 1 
ATOM   2701 C  CG2 . THR A 1 367 ? -7.623  10.593  49.855  1 23.551 ? 359  THR A CG2 1 
ATOM   2702 N  N   . PRO A 1 368 ? -10.432 9.108   51.786  1 16.588 ? 360  PRO A N   1 
ATOM   2703 C  CA  . PRO A 1 368 ? -10.579 9.046   53.247  1 15.995 ? 360  PRO A CA  1 
ATOM   2704 C  C   . PRO A 1 368 ? -9.366  9.465   54.042  1 18.229 ? 360  PRO A C   1 
ATOM   2705 O  O   . PRO A 1 368 ? -8.23   9.365   53.572  1 18.728 ? 360  PRO A O   1 
ATOM   2706 C  CB  . PRO A 1 368 ? -11.046 7.61    53.547  1 15.658 ? 360  PRO A CB  1 
ATOM   2707 C  CG  . PRO A 1 368 ? -11.548 7.129   52.191  1 17.823 ? 360  PRO A CG  1 
ATOM   2708 C  CD  . PRO A 1 368 ? -10.667 7.8     51.162  1 16.446 ? 360  PRO A CD  1 
ATOM   2709 N  N   . LYS A 1 369 ? -9.61   9.786   55.323  1 21.162 ? 361  LYS A N   1 
ATOM   2710 C  CA  . LYS A 1 369 ? -8.546  9.859   56.289  1 20.057 ? 361  LYS A CA  1 
ATOM   2711 C  C   . LYS A 1 369 ? -7.796  8.524   56.323  1 19.313 ? 361  LYS A C   1 
ATOM   2712 O  O   . LYS A 1 369 ? -8.418  7.467   56.293  1 19.435 ? 361  LYS A O   1 
ATOM   2713 C  CB  . LYS A 1 369 ? -9.241  10.103  57.63   1 22.997 ? 361  LYS A CB  1 
ATOM   2714 C  CG  . LYS A 1 369 ? -8.303  10.265  58.797  1 31.439 ? 361  LYS A CG  1 
ATOM   2715 C  CD  . LYS A 1 369 ? -8.842  10.979  60.042  1 34.456 ? 361  LYS A CD  1 
ATOM   2716 C  CE  . LYS A 1 369 ? -9.644  10.122  60.991  1 31.981 ? 361  LYS A CE  1 
ATOM   2717 N  NZ  . LYS A 1 369 ? -9.778  10.603  62.366  1 38.105 ? 361  LYS A NZ  1 
ATOM   2718 N  N   . ALA A 1 370 ? -6.459  8.596   56.447  1 19.99  ? 362  ALA A N   1 
ATOM   2719 C  CA  . ALA A 1 370 ? -5.606  7.409   56.455  1 20.217 ? 362  ALA A CA  1 
ATOM   2720 C  C   . ALA A 1 370 ? -4.558  7.552   57.534  1 16.266 ? 362  ALA A C   1 
ATOM   2721 O  O   . ALA A 1 370 ? -3.878  8.57    57.545  1 17.049 ? 362  ALA A O   1 
ATOM   2722 C  CB  . ALA A 1 370 ? -4.974  7.194   55.087  1 18.965 ? 362  ALA A CB  1 
ATOM   2723 N  N   . GLN A 1 371 ? -4.461  6.566   58.427  1 15.368 ? 363  GLN A N   1 
ATOM   2724 C  CA  . GLN A 1 371 ? -3.52   6.453   59.54   1 17.489 ? 363  GLN A CA  1 
ATOM   2725 C  C   . GLN A 1 371 ? -2.975  5.038   59.752  1 19.207 ? 363  GLN A C   1 
ATOM   2726 O  O   . GLN A 1 371 ? -3.309  4.121   59.027  1 20.701 ? 363  GLN A O   1 
ATOM   2727 C  CB  . GLN A 1 371 ? -4.276  6.853   60.813  1 20.638 ? 363  GLN A CB  1 
ATOM   2728 C  CG  . GLN A 1 371 ? -5.037  8.161   60.651  1 22.309 ? 363  GLN A CG  1 
ATOM   2729 C  CD  . GLN A 1 371 ? -5.918  8.437   61.847  1 30.795 ? 363  GLN A CD  1 
ATOM   2730 O  OE1 . GLN A 1 371 ? -6.738  7.582   62.225  1 30.187 ? 363  GLN A OE1 1 
ATOM   2731 N  NE2 . GLN A 1 371 ? -5.698  9.601   62.457  1 28.301 ? 363  GLN A NE2 1 
ATOM   2732 N  N   . PHE A 1 372 ? -2.038  4.883   60.687  1 19.891 ? 364  PHE A N   1 
ATOM   2733 C  CA  . PHE A 1 372 ? -1.563  3.629   61.218  1 20.139 ? 364  PHE A CA  1 
ATOM   2734 C  C   . PHE A 1 372 ? -2.076  3.602   62.66   1 21.796 ? 364  PHE A C   1 
ATOM   2735 O  O   . PHE A 1 372 ? -1.834  4.562   63.376  1 16.819 ? 364  PHE A O   1 
ATOM   2736 C  CB  . PHE A 1 372 ? -0.018  3.594   61.161  1 20.231 ? 364  PHE A CB  1 
ATOM   2737 C  CG  . PHE A 1 372 ? 0.632   2.255   61.505  1 23.883 ? 364  PHE A CG  1 
ATOM   2738 C  CD1 . PHE A 1 372 ? 0.569   1.167   60.622  1 23.63  ? 364  PHE A CD1 1 
ATOM   2739 C  CD2 . PHE A 1 372 ? 1.347   2.09    62.706  1 18.675 ? 364  PHE A CD2 1 
ATOM   2740 C  CE1 . PHE A 1 372 ? 1.101   -0.08   60.992  1 18.628 ? 364  PHE A CE1 1 
ATOM   2741 C  CE2 . PHE A 1 372 ? 1.93    0.869   63.047  1 17.582 ? 364  PHE A CE2 1 
ATOM   2742 C  CZ  . PHE A 1 372 ? 1.832   -0.203  62.183  1 19.095 ? 364  PHE A CZ  1 
ATOM   2743 N  N   . VAL A 1 373 ? -2.752  2.501   63.056  1 19.018 ? 365  VAL A N   1 
ATOM   2744 C  CA  . VAL A 1 373 ? -3.453  2.428   64.345  1 19.479 ? 365  VAL A CA  1 
ATOM   2745 C  C   . VAL A 1 373 ? -3.143  1.124   65.095  1 18.398 ? 365  VAL A C   1 
ATOM   2746 O  O   . VAL A 1 373 ? -2.738  0.107   64.524  1 14.244 ? 365  VAL A O   1 
ATOM   2747 C  CB  . VAL A 1 373 ? -4.985  2.639   64.141  1 19.97  ? 365  VAL A CB  1 
ATOM   2748 C  CG1 . VAL A 1 373 ? -5.364  3.971   63.495  1 19.549 ? 365  VAL A CG1 1 
ATOM   2749 C  CG2 . VAL A 1 373 ? -5.702  1.433   63.501  1 17.493 ? 365  VAL A CG2 1 
ATOM   2750 N  N   . ARG A 1 374 ? -3.347  1.14    66.421  1 16.342 ? 366  ARG A N   1 
ATOM   2751 C  CA  . ARG A 1 374 ? -3.217  -0.024  67.292  1 18.819 ? 366  ARG A CA  1 
ATOM   2752 C  C   . ARG A 1 374 ? -4.564  -0.422  67.913  1 20.36  ? 366  ARG A C   1 
ATOM   2753 O  O   . ARG A 1 374 ? -5.226  0.391   68.572  1 18.696 ? 366  ARG A O   1 
ATOM   2754 C  CB  . ARG A 1 374 ? -2.302  0.334   68.463  1 22.385 ? 366  ARG A CB  1 
ATOM   2755 C  CG  . ARG A 1 374 ? -2.159  -0.731  69.55   1 23.614 ? 366  ARG A CG  1 
ATOM   2756 C  CD  . ARG A 1 374 ? -0.846  -0.649  70.332  1 27.199 ? 366  ARG A CD  1 
ATOM   2757 N  NE  . ARG A 1 374 ? 0.351   -0.556  69.492  1 24.967 ? 366  ARG A NE  1 
ATOM   2758 C  CZ  . ARG A 1 374 ? 1.375   0.305   69.638  1 26.064 ? 366  ARG A CZ  1 
ATOM   2759 N  NH1 . ARG A 1 374 ? 1.642   0.938   70.809  1 20.223 ? 366  ARG A NH1 1 
ATOM   2760 N  NH2 . ARG A 1 374 ? 2.189   0.446   68.585  1 22.83  ? 366  ARG A NH2 1 
ATOM   2761 N  N   . TRP A 1 375 ? -4.931  -1.701  67.735  1 18.975 ? 367  TRP A N   1 
ATOM   2762 C  CA  . TRP A 1 375 ? -6.168  -2.316  68.212  1 18.971 ? 367  TRP A CA  1 
ATOM   2763 C  C   . TRP A 1 375 ? -5.887  -3.118  69.471  1 17.57  ? 367  TRP A C   1 
ATOM   2764 O  O   . TRP A 1 375 ? -4.822  -3.684  69.609  1 22.165 ? 367  TRP A O   1 
ATOM   2765 C  CB  . TRP A 1 375 ? -6.694  -3.304  67.167  1 17.362 ? 367  TRP A CB  1 
ATOM   2766 C  CG  . TRP A 1 375 ? -6.949  -2.697  65.818  1 17.067 ? 367  TRP A CG  1 
ATOM   2767 C  CD1 . TRP A 1 375 ? -6.078  -2.692  64.767  1 20.5   ? 367  TRP A CD1 1 
ATOM   2768 C  CD2 . TRP A 1 375 ? -8.145  -2.014  65.359  1 21.722 ? 367  TRP A CD2 1 
ATOM   2769 N  NE1 . TRP A 1 375 ? -6.632  -2.049  63.696  1 16.958 ? 367  TRP A NE1 1 
ATOM   2770 C  CE2 . TRP A 1 375 ? -7.902  -1.628  64.008  1 19.991 ? 367  TRP A CE2 1 
ATOM   2771 C  CE3 . TRP A 1 375 ? -9.403  -1.722  65.921  1 20.208 ? 367  TRP A CE3 1 
ATOM   2772 C  CZ2 . TRP A 1 375 ? -8.861  -0.959  63.23   1 20.671 ? 367  TRP A CZ2 1 
ATOM   2773 C  CZ3 . TRP A 1 375 ? -10.336 -1.065  65.135  1 27.438 ? 367  TRP A CZ3 1 
ATOM   2774 C  CH2 . TRP A 1 375 ? -10.082 -0.682  63.809  1 25.264 ? 367  TRP A CH2 1 
ATOM   2775 N  N   . THR A 1 376 ? -6.833  -3.149  70.399  1 16.239 ? 368  THR A N   1 
ATOM   2776 C  CA  . THR A 1 376 ? -6.761  -3.986  71.604  1 16.771 ? 368  THR A CA  1 
ATOM   2777 C  C   . THR A 1 376 ? -8.031  -4.848  71.678  1 18.817 ? 368  THR A C   1 
ATOM   2778 O  O   . THR A 1 376 ? -9.139  -4.309  71.76   1 24.402 ? 368  THR A O   1 
ATOM   2779 C  CB  . THR A 1 376 ? -6.604  -3.152  72.881  1 17.739 ? 368  THR A CB  1 
ATOM   2780 O  OG1 . THR A 1 376 ? -5.451  -2.329  72.812  1 22.537 ? 368  THR A OG1 1 
ATOM   2781 C  CG2 . THR A 1 376 ? -6.497  -4.021  74.108  1 14.444 ? 368  THR A CG2 1 
ATOM   2782 N  N   . ILE A 1 377 ? -7.87   -6.17   71.579  1 19.477 ? 369  ILE A N   1 
ATOM   2783 C  CA  . ILE A 1 377 ? -8.928  -7.183  71.658  1 14.75  ? 369  ILE A CA  1 
ATOM   2784 C  C   . ILE A 1 377 ? -8.617  -7.973  72.915  1 14.644 ? 369  ILE A C   1 
ATOM   2785 O  O   . ILE A 1 377 ? -7.686  -8.794  72.947  1 18.4   ? 369  ILE A O   1 
ATOM   2786 C  CB  . ILE A 1 377 ? -8.921  -8.132  70.447  1 14.551 ? 369  ILE A CB  1 
ATOM   2787 C  CG1 . ILE A 1 377 ? -9.064  -7.321  69.172  1 17.605 ? 369  ILE A CG1 1 
ATOM   2788 C  CG2 . ILE A 1 377 ? -10.009 -9.216  70.605  1 19.368 ? 369  ILE A CG2 1 
ATOM   2789 C  CD1 . ILE A 1 377 ? -9.017  -8.138  67.863  1 17.028 ? 369  ILE A CD1 1 
ATOM   2790 N  N   . ASP A 1 378 ? -9.237  -7.516  73.998  1 16.813 ? 370  ASP A N   1 
ATOM   2791 C  CA  . ASP A 1 378 ? -8.989  -8.141  75.295  1 16.982 ? 370  ASP A CA  1 
ATOM   2792 C  C   . ASP A 1 378 ? -9.907  -9.37   75.457  1 17.66  ? 370  ASP A C   1 
ATOM   2793 O  O   . ASP A 1 378 ? -11.112 -9.202  75.609  1 21.671 ? 370  ASP A O   1 
ATOM   2794 C  CB  . ASP A 1 378 ? -9.092  -7.109  76.397  1 15.276 ? 370  ASP A CB  1 
ATOM   2795 C  CG  . ASP A 1 378 ? -8.958  -7.603  77.837  1 18.688 ? 370  ASP A CG  1 
ATOM   2796 O  OD1 . ASP A 1 378 ? -8.88   -8.84   78.043  1 18.649 ? 370  ASP A OD1 1 
ATOM   2797 O  OD2 . ASP A 1 378 ? -8.847  -6.7    78.734  1 19.896 ? 370  ASP A OD2 1 
ATOM   2798 N  N   . PRO A 1 379 ? -9.4    -10.635 75.419  1 18.999 ? 371  PRO A N   1 
ATOM   2799 C  CA  . PRO A 1 379 ? -10.27  -11.804 75.485  1 23.51  ? 371  PRO A CA  1 
ATOM   2800 C  C   . PRO A 1 379 ? -10.976 -12.046 76.832  1 26.552 ? 371  PRO A C   1 
ATOM   2801 O  O   . PRO A 1 379 ? -11.824 -12.95  76.921  1 22.98  ? 371  PRO A O   1 
ATOM   2802 C  CB  . PRO A 1 379 ? -9.379  -12.976 75.097  1 24.881 ? 371  PRO A CB  1 
ATOM   2803 C  CG  . PRO A 1 379 ? -7.953  -12.502 75.225  1 25.515 ? 371  PRO A CG  1 
ATOM   2804 C  CD  . PRO A 1 379 ? -7.976  -10.976 75.328  1 20.27  ? 371  PRO A CD  1 
ATOM   2805 N  N   . ARG A 1 380 ? -10.624 -11.25  77.875  1 26.717 ? 372  ARG A N   1 
ATOM   2806 C  CA  . ARG A 1 380 ? -11.377 -11.269 79.141  1 27.739 ? 372  ARG A CA  1 
ATOM   2807 C  C   . ARG A 1 380 ? -12.735 -10.543 79.036  1 29.689 ? 372  ARG A C   1 
ATOM   2808 O  O   . ARG A 1 380 ? -13.537 -10.648 79.956  1 34.193 ? 372  ARG A O   1 
ATOM   2809 C  CB  . ARG A 1 380 ? -10.563 -10.647 80.286  1 24.287 ? 372  ARG A CB  1 
ATOM   2810 C  CG  . ARG A 1 380 ? -9.318  -11.459 80.584  1 21.889 ? 372  ARG A CG  1 
ATOM   2811 C  CD  . ARG A 1 380 ? -8.268  -10.655 81.324  1 25.624 ? 372  ARG A CD  1 
ATOM   2812 N  NE  . ARG A 1 380 ? -7.89   -9.341  80.788  1 24.639 ? 372  ARG A NE  1 
ATOM   2813 C  CZ  . ARG A 1 380 ? -7.079  -8.459  81.344  1 23.704 ? 372  ARG A CZ  1 
ATOM   2814 N  NH1 . ARG A 1 380 ? -6.454  -8.744  82.503  1 27.189 ? 372  ARG A NH1 1 
ATOM   2815 N  NH2 . ARG A 1 380 ? -6.947  -7.251  80.814  1 24.119 ? 372  ARG A NH2 1 
ATOM   2816 N  N   . LYS A 1 381 ? -12.964 -9.75   77.977  1 28.761 ? 373  LYS A N   1 
ATOM   2817 C  CA  . LYS A 1 381 ? -14.149 -8.91   77.83   1 28.187 ? 373  LYS A CA  1 
ATOM   2818 C  C   . LYS A 1 381 ? -15.158 -9.66   76.975  1 32.457 ? 373  LYS A C   1 
ATOM   2819 O  O   . LYS A 1 381 ? -14.803 -10.619 76.31   1 27.733 ? 373  LYS A O   1 
ATOM   2820 C  CB  . LYS A 1 381 ? -13.887 -7.519  77.233  1 37.571 ? 373  LYS A CB  1 
ATOM   2821 C  CG  . LYS A 1 381 ? -12.862 -6.647  77.95   1 38.047 ? 373  LYS A CG  1 
ATOM   2822 C  CD  . LYS A 1 381 ? -13.029 -5.158  77.687  1 38.071 ? 373  LYS A CD  1 
ATOM   2823 C  CE  . LYS A 1 381 ? -14.177 -4.566  78.472  1 38.261 ? 373  LYS A CE  1 
ATOM   2824 N  NZ  . LYS A 1 381 ? -14.04  -4.593  79.935  1 42.104 ? 373  LYS A NZ  1 
ATOM   2825 N  N   . ASP A 1 382 ? -16.427 -9.217  77.031  1 28.528 ? 374  ASP A N   1 
ATOM   2826 C  CA  . ASP A 1 382 ? -17.512 -9.752  76.25   1 27.612 ? 374  ASP A CA  1 
ATOM   2827 C  C   . ASP A 1 382 ? -17.304 -9.317  74.796  1 22.939 ? 374  ASP A C   1 
ATOM   2828 O  O   . ASP A 1 382 ? -17.29  -8.134  74.513  1 26.324 ? 374  ASP A O   1 
ATOM   2829 C  CB  . ASP A 1 382 ? -18.831 -9.273  76.847  1 34.324 ? 374  ASP A CB  1 
ATOM   2830 C  CG  . ASP A 1 382 ? -20.107 -9.626  76.095  1 36.267 ? 374  ASP A CG  1 
ATOM   2831 O  OD1 . ASP A 1 382 ? -20.013 -10.251 75.022  1 33.871 ? 374  ASP A OD1 1 
ATOM   2832 O  OD2 . ASP A 1 382 ? -21.206 -9.307  76.609  1 46.712 ? 374  ASP A OD2 1 
ATOM   2833 N  N   . ASN A 1 383 ? -17.21  -10.282 73.882  1 26.68  ? 375  ASN A N   1 
ATOM   2834 C  CA  . ASN A 1 383 ? -17     -9.97   72.466  1 25.669 ? 375  ASN A CA  1 
ATOM   2835 C  C   . ASN A 1 383 ? -18.204 -9.285  71.824  1 28.003 ? 375  ASN A C   1 
ATOM   2836 O  O   . ASN A 1 383 ? -18.075 -8.779  70.704  1 28.753 ? 375  ASN A O   1 
ATOM   2837 C  CB  . ASN A 1 383 ? -16.577 -11.187 71.652  1 22.127 ? 375  ASN A CB  1 
ATOM   2838 C  CG  . ASN A 1 383 ? -17.632 -12.261 71.624  1 26.365 ? 375  ASN A CG  1 
ATOM   2839 O  OD1 . ASN A 1 383 ? -17.947 -12.814 72.682  1 26.211 ? 375  ASN A OD1 1 
ATOM   2840 N  ND2 . ASN A 1 383 ? -18.155 -12.582 70.443  1 20.486 ? 375  ASN A ND2 1 
ATOM   2841 N  N   . ASN A 1 384 ? -19.387 -9.328  72.485  1 27.48  ? 376  ASN A N   1 
ATOM   2842 C  CA  . ASN A 1 384 ? -20.548 -8.583  72.001  1 28.316 ? 376  ASN A CA  1 
ATOM   2843 C  C   . ASN A 1 384 ? -20.421 -7.074  72.238  1 29.889 ? 376  ASN A C   1 
ATOM   2844 O  O   . ASN A 1 384 ? -21.169 -6.3    71.636  1 27.413 ? 376  ASN A O   1 
ATOM   2845 C  CB  . ASN A 1 384 ? -21.872 -9.147  72.499  1 32.738 ? 376  ASN A CB  1 
ATOM   2846 C  CG  . ASN A 1 384 ? -22.061 -10.598 72.151  1 37.383 ? 376  ASN A CG  1 
ATOM   2847 O  OD1 . ASN A 1 384 ? -22.378 -11.383 73.049  1 47.276 ? 376  ASN A OD1 1 
ATOM   2848 N  ND2 . ASN A 1 384 ? -21.917 -10.972 70.888  1 31.635 ? 376  ASN A ND2 1 
ATOM   2849 N  N   . GLU A 1 385 ? -19.489 -6.632  73.098  1 28.662 ? 377  GLU A N   1 
ATOM   2850 C  CA  . GLU A 1 385 ? -19.299 -5.207  73.295  1 28.952 ? 377  GLU A CA  1 
ATOM   2851 C  C   . GLU A 1 385 ? -18.402 -4.667  72.178  1 30.521 ? 377  GLU A C   1 
ATOM   2852 O  O   . GLU A 1 385 ? -17.361 -5.27   71.862  1 25.537 ? 377  GLU A O   1 
ATOM   2853 C  CB  . GLU A 1 385 ? -18.7   -4.98   74.686  1 34.798 ? 377  GLU A CB  1 
ATOM   2854 C  CG  . GLU A 1 385 ? -18.532 -3.511  75.078  1 33.891 ? 377  GLU A CG  1 
ATOM   2855 C  CD  . GLU A 1 385 ? -17.885 -3.462  76.463  1 42.612 ? 377  GLU A CD  1 
ATOM   2856 O  OE1 . GLU A 1 385 ? -18.536 -3.892  77.435  1 51.593 ? 377  GLU A OE1 1 
ATOM   2857 O  OE2 . GLU A 1 385 ? -16.703 -3.079  76.598  1 36.794 ? 377  GLU A OE2 1 
ATOM   2858 N  N   . GLN A 1 386 ? -18.784 -3.488  71.663  1 25.707 ? 378  GLN A N   1 
ATOM   2859 C  CA  . GLN A 1 386 ? -17.986 -2.76   70.695  1 25.503 ? 378  GLN A CA  1 
ATOM   2860 C  C   . GLN A 1 386 ? -16.574 -2.564  71.231  1 25.879 ? 378  GLN A C   1 
ATOM   2861 O  O   . GLN A 1 386 ? -16.335 -2.162  72.397  1 22.242 ? 378  GLN A O   1 
ATOM   2862 C  CB  . GLN A 1 386 ? -18.656 -1.44   70.327  1 26.331 ? 378  GLN A CB  1 
ATOM   2863 C  CG  . GLN A 1 386 ? -17.938 -0.602  69.268  1 23.707 ? 378  GLN A CG  1 
ATOM   2864 C  CD  . GLN A 1 386 ? -18.764 0.605   68.893  1 29.66  ? 378  GLN A CD  1 
ATOM   2865 O  OE1 . GLN A 1 386 ? -19.842 0.511   68.284  1 30.76  ? 378  GLN A OE1 1 
ATOM   2866 N  NE2 . GLN A 1 386 ? -18.299 1.763   69.324  1 37.649 ? 378  GLN A NE2 1 
ATOM   2867 N  N   . LEU A 1 387 ? -15.632 -2.855  70.336  1 21.294 ? 379  LEU A N   1 
ATOM   2868 C  CA  . LEU A 1 387 ? -14.221 -2.667  70.62   1 20.479 ? 379  LEU A CA  1 
ATOM   2869 C  C   . LEU A 1 387 ? -13.906 -1.234  71.032  1 21.995 ? 379  LEU A C   1 
ATOM   2870 O  O   . LEU A 1 387 ? -14.562 -0.308  70.542  1 19.636 ? 379  LEU A O   1 
ATOM   2871 C  CB  . LEU A 1 387 ? -13.376 -3.15   69.432  1 21.172 ? 379  LEU A CB  1 
ATOM   2872 C  CG  . LEU A 1 387 ? -13.169 -4.671  69.323  1 18.189 ? 379  LEU A CG  1 
ATOM   2873 C  CD1 . LEU A 1 387 ? -12.389 -4.968  68.015  1 18.221 ? 379  LEU A CD1 1 
ATOM   2874 C  CD2 . LEU A 1 387 ? -12.435 -5.271  70.533  1 21.07  ? 379  LEU A CD2 1 
ATOM   2875 N  N   . PRO A 1 388 ? -12.85  -1.015  71.889  1 21.186 ? 380  PRO A N   1 
ATOM   2876 C  CA  . PRO A 1 388 ? -12.28  0.312   72.096  1 22.243 ? 380  PRO A CA  1 
ATOM   2877 C  C   . PRO A 1 388 ? -11.787 0.924   70.793  1 25.141 ? 380  PRO A C   1 
ATOM   2878 O  O   . PRO A 1 388 ? -11.402 0.192   69.894  1 22.02  ? 380  PRO A O   1 
ATOM   2879 C  CB  . PRO A 1 388 ? -11.339 0.171   73.286  1 21.869 ? 380  PRO A CB  1 
ATOM   2880 C  CG  . PRO A 1 388 ? -10.896 -1.262  73.134  1 22.299 ? 380  PRO A CG  1 
ATOM   2881 C  CD  . PRO A 1 388 ? -12.121 -2.035  72.659  1 22.476 ? 380  PRO A CD  1 
ATOM   2882 N  N   . ASP A 1 389 ? -11.911 2.264   70.672  1 28.243 ? 381  ASP A N   1 
ATOM   2883 C  CA  . ASP A 1 389 ? -11.343 2.957   69.525  1 24.021 ? 381  ASP A CA  1 
ATOM   2884 C  C   . ASP A 1 389 ? -9.853  2.643   69.47   1 21.352 ? 381  ASP A C   1 
ATOM   2885 O  O   . ASP A 1 389 ? -9.209  2.549   70.513  1 20.953 ? 381  ASP A O   1 
ATOM   2886 C  CB  . ASP A 1 389 ? -11.614 4.459   69.536  1 29.248 ? 381  ASP A CB  1 
ATOM   2887 C  CG  . ASP A 1 389 ? -13.068 4.873   69.337  1 29.605 ? 381  ASP A CG  1 
ATOM   2888 O  OD1 . ASP A 1 389 ? -13.918 3.989   69.1    1 26.089 ? 381  ASP A OD1 1 
ATOM   2889 O  OD2 . ASP A 1 389 ? -13.378 6.067   69.546  1 35.319 ? 381  ASP A OD2 1 
ATOM   2890 N  N   . PRO A 1 390 ? -9.281  2.375   68.252  1 20.681 ? 382  PRO A N   1 
ATOM   2891 C  CA  . PRO A 1 390 ? -7.868  2.063   68.149  1 20.88  ? 382  PRO A CA  1 
ATOM   2892 C  C   . PRO A 1 390 ? -7.029  3.312   68.402  1 22.509 ? 382  PRO A C   1 
ATOM   2893 O  O   . PRO A 1 390 ? -7.514  4.429   68.168  1 22.565 ? 382  PRO A O   1 
ATOM   2894 C  CB  . PRO A 1 390 ? -7.732  1.551   66.686  1 23.279 ? 382  PRO A CB  1 
ATOM   2895 C  CG  . PRO A 1 390 ? -8.856  2.263   65.952  1 18.882 ? 382  PRO A CG  1 
ATOM   2896 C  CD  . PRO A 1 390 ? -9.988  2.306   66.962  1 19.764 ? 382  PRO A CD  1 
ATOM   2897 N  N   . GLU A 1 391 ? -5.783  3.114   68.826  1 19.799 ? 383  GLU A N   1 
ATOM   2898 C  CA  . GLU A 1 391 ? -4.934  4.253   69.138  1 24.568 ? 383  GLU A CA  1 
ATOM   2899 C  C   . GLU A 1 391 ? -4.241  4.666   67.858  1 26.231 ? 383  GLU A C   1 
ATOM   2900 O  O   . GLU A 1 391 ? -3.87   3.799   67.068  1 22.873 ? 383  GLU A O   1 
ATOM   2901 C  CB  . GLU A 1 391 ? -4.038  3.816   70.282  1 21.584 ? 383  GLU A CB  1 
ATOM   2902 C  CG  . GLU A 1 391 ? -2.934  4.797   70.658  1 30.84  ? 383  GLU A CG  1 
ATOM   2903 C  CD  . GLU A 1 391 ? -1.919  4.213   71.618  1 29.748 ? 383  GLU A CD  1 
ATOM   2904 O  OE1 . GLU A 1 391 ? -1.932  3.02    71.985  1 26.953 ? 383  GLU A OE1 1 
ATOM   2905 O  OE2 . GLU A 1 391 ? -1.065  5.019   72.007  1 38.863 ? 383  GLU A OE2 1 
ATOM   2906 N  N   . VAL A 1 392 ? -4.127  5.988   67.665  1 24.681 ? 384  VAL A N   1 
ATOM   2907 C  CA  . VAL A 1 392 ? -3.44   6.472   66.475  1 26.778 ? 384  VAL A CA  1 
ATOM   2908 C  C   . VAL A 1 392 ? -1.935  6.448   66.769  1 24.417 ? 384  VAL A C   1 
ATOM   2909 O  O   . VAL A 1 392 ? -1.457  7.047   67.762  1 20.65  ? 384  VAL A O   1 
ATOM   2910 C  CB  . VAL A 1 392 ? -4.006  7.782   65.904  1 24.134 ? 384  VAL A CB  1 
ATOM   2911 C  CG1 . VAL A 1 392 ? -3.201  8.349   64.737  1 22.864 ? 384  VAL A CG1 1 
ATOM   2912 C  CG2 . VAL A 1 392 ? -5.495  7.645   65.54   1 31.227 ? 384  VAL A CG2 1 
ATOM   2913 N  N   . ILE A 1 393 ? -1.221  5.654   65.942  1 18.454 ? 385  ILE A N   1 
ATOM   2914 C  CA  . ILE A 1 393 ? 0.216   5.461   66.087  1 20.093 ? 385  ILE A CA  1 
ATOM   2915 C  C   . ILE A 1 393 ? 0.953   6.444   65.185  1 20.909 ? 385  ILE A C   1 
ATOM   2916 O  O   . ILE A 1 393 ? 1.771   7.212   65.674  1 21.122 ? 385  ILE A O   1 
ATOM   2917 C  CB  . ILE A 1 393 ? 0.65    3.975   65.949  1 20.82  ? 385  ILE A CB  1 
ATOM   2918 C  CG1 . ILE A 1 393 ? 0.015   3.095   67.054  1 18.608 ? 385  ILE A CG1 1 
ATOM   2919 C  CG2 . ILE A 1 393 ? 2.182   3.866   65.959  1 16.792 ? 385  ILE A CG2 1 
ATOM   2920 C  CD1 . ILE A 1 393 ? 0.335   3.469   68.512  1 18.27  ? 385  ILE A CD1 1 
ATOM   2921 N  N   . LEU A 1 394 ? 0.643   6.399   63.895  1 17.74  ? 386  LEU A N   1 
ATOM   2922 C  CA  . LEU A 1 394 ? 1.054   7.409   62.938  1 23.87  ? 386  LEU A CA  1 
ATOM   2923 C  C   . LEU A 1 394 ? -0.166  8.073   62.31   1 23.219 ? 386  LEU A C   1 
ATOM   2924 O  O   . LEU A 1 394 ? -1.065  7.443   61.74   1 20.075 ? 386  LEU A O   1 
ATOM   2925 C  CB  . LEU A 1 394 ? 1.929   6.785   61.859  1 25.954 ? 386  LEU A CB  1 
ATOM   2926 C  CG  . LEU A 1 394 ? 3.193   6.032   62.295  1 24.977 ? 386  LEU A CG  1 
ATOM   2927 C  CD1 . LEU A 1 394 ? 3.823   5.558   60.965  1 26.358 ? 386  LEU A CD1 1 
ATOM   2928 C  CD2 . LEU A 1 394 ? 4.177   6.933   63.074  1 26.208 ? 386  LEU A CD2 1 
ATOM   2929 N  N   . ASP A 1 395 ? -0.155  9.394   62.373  1 21.454 ? 387  ASP A N   1 
ATOM   2930 C  CA  . ASP A 1 395 ? -1.242  10.151  61.833  1 20.543 ? 387  ASP A CA  1 
ATOM   2931 C  C   . ASP A 1 395 ? -0.855  10.576  60.436  1 23.099 ? 387  ASP A C   1 
ATOM   2932 O  O   . ASP A 1 395 ? -0.78   11.796  60.133  1 23.203 ? 387  ASP A O   1 
ATOM   2933 C  CB  . ASP A 1 395 ? -1.602  11.323  62.711  1 29.428 ? 387  ASP A CB  1 
ATOM   2934 C  CG  . ASP A 1 395 ? -2.896  12.028  62.335  1 33.97  ? 387  ASP A CG  1 
ATOM   2935 O  OD1 . ASP A 1 395 ? -3.816  11.402  61.696  1 26.625 ? 387  ASP A OD1 1 
ATOM   2936 O  OD2 . ASP A 1 395 ? -2.887  13.241  62.565  1 39.311 ? 387  ASP A OD2 1 
ATOM   2937 N  N   . THR A 1 396 ? -0.594  9.573   59.594  1 18.513 ? 388  THR A N   1 
ATOM   2938 C  CA  . THR A 1 396 ? -0.319  9.898   58.197  1 20.254 ? 388  THR A CA  1 
ATOM   2939 C  C   . THR A 1 396 ? -0.735  8.689   57.374  1 20.523 ? 388  THR A C   1 
ATOM   2940 O  O   . THR A 1 396 ? -0.73   7.59    57.903  1 19.202 ? 388  THR A O   1 
ATOM   2941 C  CB  . THR A 1 396 ? 1.187   10.226  57.993  1 22.413 ? 388  THR A CB  1 
ATOM   2942 O  OG1 . THR A 1 396 ? 1.448   10.932  56.778  1 21.768 ? 388  THR A OG1 1 
ATOM   2943 C  CG2 . THR A 1 396 ? 2.163   9.055   58.04   1 24.824 ? 388  THR A CG2 1 
ATOM   2944 N  N   . PRO A 1 397 ? -1.045  8.858   56.086  1 21.111 ? 389  PRO A N   1 
ATOM   2945 C  CA  . PRO A 1 397 ? -1.35   7.718   55.234  1 24.834 ? 389  PRO A CA  1 
ATOM   2946 C  C   . PRO A 1 397 ? -0.231  6.69    55.22   1 22.393 ? 389  PRO A C   1 
ATOM   2947 O  O   . PRO A 1 397 ? 0.909   7.066   54.992  1 23.958 ? 389  PRO A O   1 
ATOM   2948 C  CB  . PRO A 1 397 ? -1.6    8.349   53.864  1 24.216 ? 389  PRO A CB  1 
ATOM   2949 C  CG  . PRO A 1 397 ? -2.007  9.803   54.188  1 24.207 ? 389  PRO A CG  1 
ATOM   2950 C  CD  . PRO A 1 397 ? -1.194  10.142  55.381  1 21.146 ? 389  PRO A CD  1 
ATOM   2951 N  N   . SER A 1 398 ? -0.579  5.422   55.504  1 18.807 ? 390  SER A N   1 
ATOM   2952 C  CA  . SER A 1 398 ? 0.384   4.38    55.875  1 17.733 ? 390  SER A CA  1 
ATOM   2953 C  C   . SER A 1 398 ? -0.117  3.084   55.275  1 19.185 ? 390  SER A C   1 
ATOM   2954 O  O   . SER A 1 398 ? -1.315  2.83    55.273  1 20.637 ? 390  SER A O   1 
ATOM   2955 C  CB  . SER A 1 398 ? 0.415   4.173   57.395  1 16.587 ? 390  SER A CB  1 
ATOM   2956 O  OG  . SER A 1 398 ? 1.041   5.319   57.992  1 20.023 ? 390  SER A OG  1 
ATOM   2957 N  N   . GLU A 1 399 ? 0.804   2.264   54.766  1 19.745 ? 391  GLU A N   1 
ATOM   2958 C  CA  . GLU A 1 399 ? 0.402   1.005   54.161  1 20.873 ? 391  GLU A CA  1 
ATOM   2959 C  C   . GLU A 1 399 ? 1.609   0.097   54.013  1 14.18  ? 391  GLU A C   1 
ATOM   2960 O  O   . GLU A 1 399 ? 2.688   0.444   54.482  1 16.161 ? 391  GLU A O   1 
ATOM   2961 C  CB  . GLU A 1 399 ? -0.425  1.161   52.869  1 15.718 ? 391  GLU A CB  1 
ATOM   2962 C  CG  . GLU A 1 399 ? -1.851  0.646   53.062  1 16.499 ? 391  GLU A CG  1 
ATOM   2963 C  CD  . GLU A 1 399 ? -1.82   -0.833  53.34   1 18.162 ? 391  GLU A CD  1 
ATOM   2964 O  OE1 . GLU A 1 399 ? -1.298  -1.571  52.503  1 21.545 ? 391  GLU A OE1 1 
ATOM   2965 O  OE2 . GLU A 1 399 ? -2.112  -1.231  54.46   1 20.613 ? 391  GLU A OE2 1 
ATOM   2966 N  N   . PHE A 1 400 ? 1.352   -1.118  53.522  1 14.747 ? 392  PHE A N   1 
ATOM   2967 C  CA  . PHE A 1 400 ? 2.284   -2.228  53.414  1 13.538 ? 392  PHE A CA  1 
ATOM   2968 C  C   . PHE A 1 400 ? 3.295   -2.244  54.527  1 12.636 ? 392  PHE A C   1 
ATOM   2969 O  O   . PHE A 1 400 ? 4.5     -2.076  54.286  1 16.196 ? 392  PHE A O   1 
ATOM   2970 C  CB  . PHE A 1 400 ? 3.039   -2.086  52.097  1 14.596 ? 392  PHE A CB  1 
ATOM   2971 C  CG  . PHE A 1 400 ? 2.162   -2.232  50.859  1 16.28  ? 392  PHE A CG  1 
ATOM   2972 C  CD1 . PHE A 1 400 ? 1.63    -3.484  50.555  1 17.706 ? 392  PHE A CD1 1 
ATOM   2973 C  CD2 . PHE A 1 400 ? 1.846   -1.131  50.051  1 15.736 ? 392  PHE A CD2 1 
ATOM   2974 C  CE1 . PHE A 1 400 ? 0.823   -3.655  49.421  1 20.314 ? 392  PHE A CE1 1 
ATOM   2975 C  CE2 . PHE A 1 400 ? 1.088   -1.309  48.893  1 14.715 ? 392  PHE A CE2 1 
ATOM   2976 C  CZ  . PHE A 1 400 ? 0.569   -2.569  48.613  1 18.93  ? 392  PHE A CZ  1 
ATOM   2977 N  N   . PRO A 1 401 ? 2.852   -2.491  55.777  1 14.561 ? 393  PRO A N   1 
ATOM   2978 C  CA  . PRO A 1 401 ? 3.788   -2.674  56.853  1 13.769 ? 393  PRO A CA  1 
ATOM   2979 C  C   . PRO A 1 401 ? 4.438   -4.063  56.905  1 13.157 ? 393  PRO A C   1 
ATOM   2980 O  O   . PRO A 1 401 ? 3.755   -5.072  56.677  1 14.543 ? 393  PRO A O   1 
ATOM   2981 C  CB  . PRO A 1 401 ? 2.93    -2.451  58.091  1 13.052 ? 393  PRO A CB  1 
ATOM   2982 C  CG  . PRO A 1 401 ? 1.548   -2.891  57.672  1 14.848 ? 393  PRO A CG  1 
ATOM   2983 C  CD  . PRO A 1 401 ? 1.437   -2.649  56.187  1 15.533 ? 393  PRO A CD  1 
ATOM   2984 N  N   . GLN A 1 402 ? 5.718   -4.125  57.315  1 13.408 ? 394  GLN A N   1 
ATOM   2985 C  CA  . GLN A 1 402 ? 6.361   -5.384  57.655  1 16.127 ? 394  GLN A CA  1 
ATOM   2986 C  C   . GLN A 1 402 ? 7.045   -5.224  59.015  1 17.842 ? 394  GLN A C   1 
ATOM   2987 O  O   . GLN A 1 402 ? 7.125   -4.103  59.555  1 18.439 ? 394  GLN A O   1 
ATOM   2988 C  CB  . GLN A 1 402 ? 7.332   -5.973  56.634  1 15.446 ? 394  GLN A CB  1 
ATOM   2989 C  CG  . GLN A 1 402 ? 6.703   -6.239  55.268  1 14.767 ? 394  GLN A CG  1 
ATOM   2990 C  CD  . GLN A 1 402 ? 7.429   -7.315  54.504  1 15.272 ? 394  GLN A CD  1 
ATOM   2991 O  OE1 . GLN A 1 402 ? 8.389   -7.887  54.992  1 24.022 ? 394  GLN A OE1 1 
ATOM   2992 N  NE2 . GLN A 1 402 ? 6.926   -7.728  53.335  1 14.046 ? 394  GLN A NE2 1 
ATOM   2993 N  N   . ILE A 1 403 ? 7.49    -6.344  59.558  1 14.418 ? 395  ILE A N   1 
ATOM   2994 C  CA  . ILE A 1 403 ? 8.144   -6.354  60.869  1 16.661 ? 395  ILE A CA  1 
ATOM   2995 C  C   . ILE A 1 403 ? 9.5     -7.057  60.747  1 16.657 ? 395  ILE A C   1 
ATOM   2996 O  O   . ILE A 1 403 ? 9.917   -7.447  59.603  1 14.83  ? 395  ILE A O   1 
ATOM   2997 C  CB  . ILE A 1 403 ? 7.201   -7.01   61.908  1 13.194 ? 395  ILE A CB  1 
ATOM   2998 C  CG1 . ILE A 1 403 ? 6.97    -8.567  61.776  1 14.002 ? 395  ILE A CG1 1 
ATOM   2999 C  CG2 . ILE A 1 403 ? 5.907   -6.217  62.023  1 13.799 ? 395  ILE A CG2 1 
ATOM   3000 C  CD1 . ILE A 1 403 ? 6.787   -9.277  63.144  1 12.919 ? 395  ILE A CD1 1 
ATOM   3001 N  N   . ASP A 1 404 ? 10.157  -7.262  61.92   1 16.801 ? 396  ASP A N   1 
ATOM   3002 C  CA  . ASP A 1 404 ? 11.278  -8.215  61.978  1 18.633 ? 396  ASP A CA  1 
ATOM   3003 C  C   . ASP A 1 404 ? 10.687  -9.61   62.2    1 17.563 ? 396  ASP A C   1 
ATOM   3004 O  O   . ASP A 1 404 ? 10.265  -9.924  63.302  1 16.228 ? 396  ASP A O   1 
ATOM   3005 C  CB  . ASP A 1 404 ? 12.328  -7.787  63.025  1 17.371 ? 396  ASP A CB  1 
ATOM   3006 C  CG  . ASP A 1 404 ? 13.576  -8.63   63.211  1 18.228 ? 396  ASP A CG  1 
ATOM   3007 O  OD1 . ASP A 1 404 ? 13.657  -9.821  62.735  1 18.038 ? 396  ASP A OD1 1 
ATOM   3008 O  OD2 . ASP A 1 404 ? 14.496  -8.1    63.906  1 23.656 ? 396  ASP A OD2 1 
ATOM   3009 N  N   . ASN A 1 405 ? 10.707  -10.476 61.164  1 17.264 ? 397  ASN A N   1 
ATOM   3010 C  CA  . ASN A 1 405 ? 10.045  -11.784 61.21   1 20.133 ? 397  ASN A CA  1 
ATOM   3011 C  C   . ASN A 1 405 ? 10.602  -12.743 62.258  1 20.672 ? 397  ASN A C   1 
ATOM   3012 O  O   . ASN A 1 405 ? 9.995   -13.752 62.556  1 21.903 ? 397  ASN A O   1 
ATOM   3013 C  CB  . ASN A 1 405 ? 10.025  -12.433 59.834  1 19.6   ? 397  ASN A CB  1 
ATOM   3014 C  CG  . ASN A 1 405 ? 8.927   -11.748 59.063  1 22.267 ? 397  ASN A CG  1 
ATOM   3015 O  OD1 . ASN A 1 405 ? 8.032   -11.124 59.655  1 21.334 ? 397  ASN A OD1 1 
ATOM   3016 N  ND2 . ASN A 1 405 ? 8.963   -11.807 57.741  1 23.717 ? 397  ASN A ND2 1 
ATOM   3017 N  N   . ARG A 1 406 ? 11.793  -12.496 62.795  1 21.555 ? 398  ARG A N   1 
ATOM   3018 C  CA  . ARG A 1 406 ? 12.245  -13.268 63.952  1 22.206 ? 398  ARG A CA  1 
ATOM   3019 C  C   . ARG A 1 406 ? 11.335  -13.108 65.178  1 21.04  ? 398  ARG A C   1 
ATOM   3020 O  O   . ARG A 1 406 ? 11.506  -13.789 66.214  1 19.624 ? 398  ARG A O   1 
ATOM   3021 C  CB  . ARG A 1 406 ? 13.684  -12.847 64.258  1 22.872 ? 398  ARG A CB  1 
ATOM   3022 C  CG  . ARG A 1 406 ? 14.728  -13.325 63.248  1 22.698 ? 398  ARG A CG  1 
ATOM   3023 C  CD  . ARG A 1 406 ? 16.102  -12.676 63.646  1 22.206 ? 398  ARG A CD  1 
ATOM   3024 N  NE  . ARG A 1 406 ? 16.022  -11.212 63.821  1 20.549 ? 398  ARG A NE  1 
ATOM   3025 C  CZ  . ARG A 1 406 ? 16.987  -10.449 64.367  1 21.592 ? 398  ARG A CZ  1 
ATOM   3026 N  NH1 . ARG A 1 406 ? 18.112  -11.013 64.768  1 25.008 ? 398  ARG A NH1 1 
ATOM   3027 N  NH2 . ARG A 1 406 ? 16.844  -9.134  64.539  1 20.483 ? 398  ARG A NH2 1 
ATOM   3028 N  N   . PHE A 1 407 ? 10.369  -12.197 65.052  1 21.991 ? 399  PHE A N   1 
ATOM   3029 C  CA  . PHE A 1 407 ? 9.425   -11.85  66.109  1 21.583 ? 399  PHE A CA  1 
ATOM   3030 C  C   . PHE A 1 407 ? 8.005   -12.137 65.634  1 21.446 ? 399  PHE A C   1 
ATOM   3031 O  O   . PHE A 1 407 ? 7.045   -11.742 66.28   1 16.665 ? 399  PHE A O   1 
ATOM   3032 C  CB  . PHE A 1 407 ? 9.661   -10.431 66.635  1 23.924 ? 399  PHE A CB  1 
ATOM   3033 C  CG  . PHE A 1 407 ? 11.04   -10.261 67.263  1 30.371 ? 399  PHE A CG  1 
ATOM   3034 C  CD1 . PHE A 1 407 ? 12.165  -10.018 66.456  1 32.696 ? 399  PHE A CD1 1 
ATOM   3035 C  CD2 . PHE A 1 407 ? 11.242  -10.433 68.645  1 29.06  ? 399  PHE A CD2 1 
ATOM   3036 C  CE1 . PHE A 1 407 ? 13.452  -9.925  66.985  1 29.068 ? 399  PHE A CE1 1 
ATOM   3037 C  CE2 . PHE A 1 407 ? 12.537  -10.301 69.181  1 30.776 ? 399  PHE A CE2 1 
ATOM   3038 C  CZ  . PHE A 1 407 ? 13.63   -10.027 68.355  1 34.636 ? 399  PHE A CZ  1 
ATOM   3039 N  N   . MET A 1 408 ? 7.87    -12.887 64.53   1 18.799 ? 400  MET A N   1 
ATOM   3040 C  CA  . MET A 1 408 ? 6.532   -13.179 64.029  1 20.486 ? 400  MET A CA  1 
ATOM   3041 C  C   . MET A 1 408 ? 5.779   -14.123 64.992  1 20.154 ? 400  MET A C   1 
ATOM   3042 O  O   . MET A 1 408 ? 6.288   -15.185 65.297  1 24.418 ? 400  MET A O   1 
ATOM   3043 C  CB  . MET A 1 408 ? 6.608   -13.68  62.562  1 16.406 ? 400  MET A CB  1 
ATOM   3044 C  CG  . MET A 1 408 ? 5.263   -14.131 62.009  1 14.94  ? 400  MET A CG  1 
ATOM   3045 S  SD  . MET A 1 408 ? 3.954   -12.899 62.124  1 19.076 ? 400  MET A SD  1 
ATOM   3046 C  CE  . MET A 1 408 ? 4.578   -11.705 60.945  1 16.414 ? 400  MET A CE  1 
ATOM   3047 N  N   . GLY A 1 409 ? 4.56    -13.73  65.424  1 18.755 ? 401  GLY A N   1 
ATOM   3048 C  CA  . GLY A 1 409 ? 3.682   -14.536 66.275  1 17.008 ? 401  GLY A CA  1 
ATOM   3049 C  C   . GLY A 1 409 ? 4.06    -14.431 67.765  1 19.792 ? 401  GLY A C   1 
ATOM   3050 O  O   . GLY A 1 409 ? 3.597   -15.23  68.575  1 22.459 ? 401  GLY A O   1 
ATOM   3051 N  N   . VAL A 1 410 ? 4.93    -13.479 68.109  1 18.738 ? 402  VAL A N   1 
ATOM   3052 C  CA  . VAL A 1 410 ? 5.287   -13.182 69.505  1 20.414 ? 402  VAL A CA  1 
ATOM   3053 C  C   . VAL A 1 410 ? 5.331   -11.668 69.615  1 22.159 ? 402  VAL A C   1 
ATOM   3054 O  O   . VAL A 1 410 ? 5.174   -10.995 68.585  1 22.21  ? 402  VAL A O   1 
ATOM   3055 C  CB  . VAL A 1 410 ? 6.643   -13.802 69.929  1 19.53  ? 402  VAL A CB  1 
ATOM   3056 C  CG1 . VAL A 1 410 ? 6.665   -15.324 69.974  1 18.831 ? 402  VAL A CG1 1 
ATOM   3057 C  CG2 . VAL A 1 410 ? 7.803   -13.304 69.067  1 16.99  ? 402  VAL A CG2 1 
ATOM   3058 N  N   . GLU A 1 411 ? 5.599   -11.131 70.833  1 17.643 ? 403  GLU A N   1 
ATOM   3059 C  CA  . GLU A 1 411 ? 5.742   -9.68   71.008  1 18.471 ? 403  GLU A CA  1 
ATOM   3060 C  C   . GLU A 1 411 ? 6.783   -9.096  70.047  1 17.699 ? 403  GLU A C   1 
ATOM   3061 O  O   . GLU A 1 411 ? 7.874   -9.64   70.016  1 21.654 ? 403  GLU A O   1 
ATOM   3062 C  CB  . GLU A 1 411 ? 5.993   -9.347  72.491  1 18.021 ? 403  GLU A CB  1 
ATOM   3063 C  CG  . GLU A 1 411 ? 6.34    -7.891  72.728  1 18.532 ? 403  GLU A CG  1 
ATOM   3064 C  CD  . GLU A 1 411 ? 6.336   -7.45   74.193  1 22.783 ? 403  GLU A CD  1 
ATOM   3065 O  OE1 . GLU A 1 411 ? 6.15    -8.323  75.087  1 23.434 ? 403  GLU A OE1 1 
ATOM   3066 O  OE2 . GLU A 1 411 ? 6.443   -6.236  74.385  1 25.113 ? 403  GLU A OE2 1 
ATOM   3067 N  N   . TYR A 1 412 ? 6.416   -8.001  69.358  1 18.146 ? 404  TYR A N   1 
ATOM   3068 C  CA  . TYR A 1 412 ? 7.247   -7.276  68.4    1 17.297 ? 404  TYR A CA  1 
ATOM   3069 C  C   . TYR A 1 412 ? 7.209   -5.801  68.762  1 20.236 ? 404  TYR A C   1 
ATOM   3070 O  O   . TYR A 1 412 ? 6.245   -5.351  69.402  1 17.627 ? 404  TYR A O   1 
ATOM   3071 C  CB  . TYR A 1 412 ? 6.918   -7.65   66.935  1 16.887 ? 404  TYR A CB  1 
ATOM   3072 C  CG  . TYR A 1 412 ? 5.733   -6.834  66.456  1 16.796 ? 404  TYR A CG  1 
ATOM   3073 C  CD1 . TYR A 1 412 ? 4.419   -7.228  66.768  1 18.231 ? 404  TYR A CD1 1 
ATOM   3074 C  CD2 . TYR A 1 412 ? 5.924   -5.696  65.698  1 18.107 ? 404  TYR A CD2 1 
ATOM   3075 C  CE1 . TYR A 1 412 ? 3.329   -6.456  66.396  1 18.51  ? 404  TYR A CE1 1 
ATOM   3076 C  CE2 . TYR A 1 412 ? 4.849   -4.905  65.314  1 18.76  ? 404  TYR A CE2 1 
ATOM   3077 C  CZ  . TYR A 1 412 ? 3.554   -5.307  65.636  1 20.697 ? 404  TYR A CZ  1 
ATOM   3078 O  OH  . TYR A 1 412 ? 2.491   -4.518  65.254  1 18.629 ? 404  TYR A OH  1 
ATOM   3079 N  N   . SER A 1 413 ? 8.277   -5.067  68.342  1 15.462 ? 405  SER A N   1 
ATOM   3080 C  CA  . SER A 1 413 ? 8.417   -3.632  68.499  1 19.331 ? 405  SER A CA  1 
ATOM   3081 C  C   . SER A 1 413 ? 8.587   -2.885  67.174  1 17.235 ? 405  SER A C   1 
ATOM   3082 O  O   . SER A 1 413 ? 8.017   -1.808  66.986  1 20.422 ? 405  SER A O   1 
ATOM   3083 C  CB  . SER A 1 413 ? 9.587   -3.343  69.409  1 21.613 ? 405  SER A CB  1 
ATOM   3084 O  OG  . SER A 1 413 ? 9.554   -1.964  69.701  1 22.662 ? 405  SER A OG  1 
ATOM   3085 N  N   . SER A 1 414 ? 9.392   -3.454  66.289  1 18.203 ? 406  SER A N   1 
ATOM   3086 C  CA  . SER A 1 414 ? 9.712   -2.837  65.007  1 19.645 ? 406  SER A CA  1 
ATOM   3087 C  C   . SER A 1 414 ? 8.581   -2.949  63.986  1 15.719 ? 406  SER A C   1 
ATOM   3088 O  O   . SER A 1 414 ? 8.084   -4.048  63.766  1 17.527 ? 406  SER A O   1 
ATOM   3089 C  CB  . SER A 1 414 ? 11.069  -3.27   64.493  1 23.571 ? 406  SER A CB  1 
ATOM   3090 O  OG  . SER A 1 414 ? 12.078  -2.432  65.064  1 22.124 ? 406  SER A OG  1 
ATOM   3091 N  N   . ALA A 1 415 ? 8.24    -1.815  63.345  1 16.011 ? 407  ALA A N   1 
ATOM   3092 C  CA  . ALA A 1 415 ? 7.485   -1.882  62.084  1 16.306 ? 407  ALA A CA  1 
ATOM   3093 C  C   . ALA A 1 415 ? 8.129   -1      61.031  1 19.938 ? 407  ALA A C   1 
ATOM   3094 O  O   . ALA A 1 415 ? 8.609   0.093   61.332  1 19.405 ? 407  ALA A O   1 
ATOM   3095 C  CB  . ALA A 1 415 ? 6.055   -1.477  62.33   1 15.696 ? 407  ALA A CB  1 
ATOM   3096 N  N   . PHE A 1 416 ? 8.042   -1.469  59.788  1 18.519 ? 408  PHE A N   1 
ATOM   3097 C  CA  . PHE A 1 416 ? 8.679   -0.802  58.661  1 16.834 ? 408  PHE A CA  1 
ATOM   3098 C  C   . PHE A 1 416 ? 7.508   -0.562  57.728  1 16.373 ? 408  PHE A C   1 
ATOM   3099 O  O   . PHE A 1 416 ? 6.886   -1.545  57.359  1 16.877 ? 408  PHE A O   1 
ATOM   3100 C  CB  . PHE A 1 416 ? 9.703   -1.738  57.986  1 17.488 ? 408  PHE A CB  1 
ATOM   3101 C  CG  . PHE A 1 416 ? 10.816  -2.215  58.91   1 16.499 ? 408  PHE A CG  1 
ATOM   3102 C  CD1 . PHE A 1 416 ? 11.839  -1.345  59.271  1 16.559 ? 408  PHE A CD1 1 
ATOM   3103 C  CD2 . PHE A 1 416 ? 10.79   -3.503  59.443  1 16.28  ? 408  PHE A CD2 1 
ATOM   3104 C  CE1 . PHE A 1 416 ? 12.828  -1.738  60.181  1 21.659 ? 408  PHE A CE1 1 
ATOM   3105 C  CE2 . PHE A 1 416 ? 11.792  -3.912  60.322  1 24.582 ? 408  PHE A CE2 1 
ATOM   3106 C  CZ  . PHE A 1 416 ? 12.805  -3.022  60.705  1 19.591 ? 408  PHE A CZ  1 
ATOM   3107 N  N   . ILE A 1 417 ? 7.119   0.704   57.526  1 15.185 ? 409  ILE A N   1 
ATOM   3108 C  CA  . ILE A 1 417 ? 5.764   1.075   57.057  1 15.823 ? 409  ILE A CA  1 
ATOM   3109 C  C   . ILE A 1 417 ? 5.961   1.9     55.807  1 15.586 ? 409  ILE A C   1 
ATOM   3110 O  O   . ILE A 1 417 ? 6.846   2.773   55.756  1 14.73  ? 409  ILE A O   1 
ATOM   3111 C  CB  . ILE A 1 417 ? 5.039   1.895   58.136  1 14.737 ? 409  ILE A CB  1 
ATOM   3112 C  CG1 . ILE A 1 417 ? 5.122   1.157   59.508  1 18.358 ? 409  ILE A CG1 1 
ATOM   3113 C  CG2 . ILE A 1 417 ? 3.598   2.206   57.716  1 20.168 ? 409  ILE A CG2 1 
ATOM   3114 C  CD1 . ILE A 1 417 ? 4.528   1.934   60.682  1 17.29  ? 409  ILE A CD1 1 
ATOM   3115 N  N   . ASN A 1 418 ? 5.194   1.621   54.768  1 13.653 ? 410  ASN A N   1 
ATOM   3116 C  CA  . ASN A 1 418 ? 5.297   2.463   53.598  1 13.062 ? 410  ASN A CA  1 
ATOM   3117 C  C   . ASN A 1 418 ? 4.43    3.677   53.894  1 13.243 ? 410  ASN A C   1 
ATOM   3118 O  O   . ASN A 1 418 ? 3.318   3.487   54.374  1 14.656 ? 410  ASN A O   1 
ATOM   3119 C  CB  . ASN A 1 418 ? 4.856   1.587   52.434  1 11.554 ? 410  ASN A CB  1 
ATOM   3120 C  CG  . ASN A 1 418 ? 5.096   2.014   51.018  1 13.927 ? 410  ASN A CG  1 
ATOM   3121 O  OD1 . ASN A 1 418 ? 4.6     1.264   50.142  1 14.55  ? 410  ASN A OD1 1 
ATOM   3122 N  ND2 . ASN A 1 418 ? 5.874   3.061   50.735  1 13.88  ? 410  ASN A ND2 1 
ATOM   3123 N  N   . VAL A 1 419 ? 4.886   4.909   53.603  1 15.115 ? 411  VAL A N   1 
ATOM   3124 C  CA  . VAL A 1 419 ? 4.158   6.088   54.089  1 17.585 ? 411  VAL A CA  1 
ATOM   3125 C  C   . VAL A 1 419 ? 4.05    7.184   53.036  1 22.378 ? 411  VAL A C   1 
ATOM   3126 O  O   . VAL A 1 419 ? 4.965   7.336   52.2    1 20.235 ? 411  VAL A O   1 
ATOM   3127 C  CB  . VAL A 1 419 ? 4.705   6.666   55.433  1 21.62  ? 411  VAL A CB  1 
ATOM   3128 C  CG1 . VAL A 1 419 ? 4.531   5.709   56.599  1 16.689 ? 411  VAL A CG1 1 
ATOM   3129 C  CG2 . VAL A 1 419 ? 6.186   7.072   55.342  1 20.743 ? 411  VAL A CG2 1 
ATOM   3130 N  N   . PHE A 1 420 ? 2.965   8.009   53.162  1 20.533 ? 412  PHE A N   1 
ATOM   3131 C  CA  . PHE A 1 420 ? 2.946   9.39    52.637  1 20.446 ? 412  PHE A CA  1 
ATOM   3132 C  C   . PHE A 1 420 ? 3.784   10.234  53.613  1 24.854 ? 412  PHE A C   1 
ATOM   3133 O  O   . PHE A 1 420 ? 3.467   10.301  54.815  1 23.479 ? 412  PHE A O   1 
ATOM   3134 C  CB  . PHE A 1 420 ? 1.546   10.04   52.51   1 21.308 ? 412  PHE A CB  1 
ATOM   3135 C  CG  . PHE A 1 420 ? 0.567   9.514   51.449  1 26.92  ? 412  PHE A CG  1 
ATOM   3136 C  CD1 . PHE A 1 420 ? 0.55    8.15    51.095  1 20.245 ? 412  PHE A CD1 1 
ATOM   3137 C  CD2 . PHE A 1 420 ? -0.397  10.357  50.873  1 21.164 ? 412  PHE A CD2 1 
ATOM   3138 C  CE1 . PHE A 1 420 ? -0.353  7.653   50.159  1 19.192 ? 412  PHE A CE1 1 
ATOM   3139 C  CE2 . PHE A 1 420 ? -1.347  9.852   49.976  1 27.45  ? 412  PHE A CE2 1 
ATOM   3140 C  CZ  . PHE A 1 420 ? -1.345  8.481   49.641  1 21.47  ? 412  PHE A CZ  1 
ATOM   3141 N  N   . VAL A 1 421 ? 4.922   10.788  53.138  1 24.289 ? 413  VAL A N   1 
ATOM   3142 C  CA  . VAL A 1 421 ? 5.794   11.525  54.055  1 21.688 ? 413  VAL A CA  1 
ATOM   3143 C  C   . VAL A 1 421 ? 5.084   12.792  54.546  1 19.523 ? 413  VAL A C   1 
ATOM   3144 O  O   . VAL A 1 421 ? 4.616   13.589  53.725  1 20.951 ? 413  VAL A O   1 
ATOM   3145 C  CB  . VAL A 1 421 ? 7.21    11.756  53.483  1 23.002 ? 413  VAL A CB  1 
ATOM   3146 C  CG1 . VAL A 1 421 ? 8.069   12.616  54.422  1 24.507 ? 413  VAL A CG1 1 
ATOM   3147 C  CG2 . VAL A 1 421 ? 7.895   10.416  53.219  1 21.568 ? 413  VAL A CG2 1 
ATOM   3148 N  N   . PRO A 1 422 ? 4.952   12.996  55.886  1 19.613 ? 414  PRO A N   1 
ATOM   3149 C  CA  . PRO A 1 422 ? 4.364   14.219  56.42   1 22.459 ? 414  PRO A CA  1 
ATOM   3150 C  C   . PRO A 1 422 ? 4.961   15.503  55.858  1 23.833 ? 414  PRO A C   1 
ATOM   3151 O  O   . PRO A 1 422 ? 6.175   15.629  55.783  1 22.208 ? 414  PRO A O   1 
ATOM   3152 C  CB  . PRO A 1 422 ? 4.412   14.069  57.951  1 17.859 ? 414  PRO A CB  1 
ATOM   3153 C  CG  . PRO A 1 422 ? 4.892   12.69   58.263  1 20.881 ? 414  PRO A CG  1 
ATOM   3154 C  CD  . PRO A 1 422 ? 5.253   12.016  56.945  1 20.516 ? 414  PRO A CD  1 
ATOM   3155 N  N   . ASP A 1 423 ? 4.044   16.372  55.386  1 29.002 ? 415  ASP A N   1 
ATOM   3156 C  CA  . ASP A 1 423 ? 4.279   17.707  54.864  1 29.429 ? 415  ASP A CA  1 
ATOM   3157 C  C   . ASP A 1 423 ? 4.901   17.646  53.472  1 28.217 ? 415  ASP A C   1 
ATOM   3158 O  O   . ASP A 1 423 ? 5.132   18.711  52.923  1 28.589 ? 415  ASP A O   1 
ATOM   3159 C  CB  . ASP A 1 423 ? 4.996   18.577  55.894  1 30.212 ? 415  ASP A CB  1 
ATOM   3160 C  CG  . ASP A 1 423 ? 4.259   18.716  57.22   1 39.533 ? 415  ASP A CG  1 
ATOM   3161 O  OD1 . ASP A 1 423 ? 3.04    19.071  57.191  1 39.252 ? 415  ASP A OD1 1 
ATOM   3162 O  OD2 . ASP A 1 423 ? 4.899   18.455  58.263  1 32.934 ? 415  ASP A OD2 1 
ATOM   3163 N  N   . ARG A 1 424 ? 5.145   16.423  52.926  1 31.327 ? 416  ARG A N   1 
ATOM   3164 C  CA  . ARG A 1 424 ? 5.931   16.236  51.703  1 26.715 ? 416  ARG A CA  1 
ATOM   3165 C  C   . ARG A 1 424 ? 5.247   15.291  50.709  1 28.391 ? 416  ARG A C   1 
ATOM   3166 O  O   . ARG A 1 424 ? 5.881   14.682  49.842  1 28.962 ? 416  ARG A O   1 
ATOM   3167 C  CB  . ARG A 1 424 ? 7.379   15.811  51.978  1 28.312 ? 416  ARG A CB  1 
ATOM   3168 C  CG  . ARG A 1 424 ? 8.228   16.644  52.926  1 29.084 ? 416  ARG A CG  1 
ATOM   3169 C  CD  . ARG A 1 424 ? 9.553   15.954  53.034  1 26.983 ? 416  ARG A CD  1 
ATOM   3170 N  NE  . ARG A 1 424 ? 10.313  16.205  51.795  1 28.689 ? 416  ARG A NE  1 
ATOM   3171 C  CZ  . ARG A 1 424 ? 11.659  16.021  51.701  1 33.471 ? 416  ARG A CZ  1 
ATOM   3172 N  NH1 . ARG A 1 424 ? 12.309  15.373  52.664  1 33.237 ? 416  ARG A NH1 1 
ATOM   3173 N  NH2 . ARG A 1 424 ? 12.364  16.487  50.657  1 28.762 ? 416  ARG A NH2 1 
ATOM   3174 N  N   . SER A 1 425 ? 3.914   15.301  50.709  1 28.672 ? 417  SER A N   1 
ATOM   3175 C  CA  . SER A 1 425 ? 3.114   14.338  49.959  1 26.47  ? 417  SER A CA  1 
ATOM   3176 C  C   . SER A 1 425 ? 1.776   14.995  49.624  1 32.109 ? 417  SER A C   1 
ATOM   3177 O  O   . SER A 1 425 ? 1.425   16.023  50.228  1 25.736 ? 417  SER A O   1 
ATOM   3178 C  CB  . SER A 1 425 ? 2.957   13.083  50.769  1 25.072 ? 417  SER A CB  1 
ATOM   3179 O  OG  . SER A 1 425 ? 2.559   13.344  52.108  1 24.962 ? 417  SER A OG  1 
ATOM   3180 N  N   . ASP A 1 426 ? 1.058   14.408  48.66   1 36.245 ? 418  ASP A N   1 
ATOM   3181 C  CA  . ASP A 1 426 ? -0.161  15.023  48.151  1 42.994 ? 418  ASP A CA  1 
ATOM   3182 C  C   . ASP A 1 426 ? -1.247  15.231  49.229  1 47.449 ? 418  ASP A C   1 
ATOM   3183 O  O   . ASP A 1 426 ? -1.565  16.385  49.542  1 69.418 ? 418  ASP A O   1 
ATOM   3184 C  CB  . ASP A 1 426 ? -0.426  14.582  46.722  1 38.263 ? 418  ASP A CB  1 
ATOM   3185 C  CG  . ASP A 1 426 ? -1.656  15.187  46.069  1 32.232 ? 418  ASP A CG  1 
ATOM   3186 O  OD1 . ASP A 1 426 ? -2.552  15.632  46.812  1 30.642 ? 418  ASP A OD1 1 
ATOM   3187 O  OD2 . ASP A 1 426 ? -1.703  15.18   44.824  1 32.852 ? 418  ASP A OD2 1 
ATOM   3188 N  N   . GLY A 1 427 ? -1.777  14.149  49.822  1 42.905 ? 419  GLY A N   1 
ATOM   3189 C  CA  . GLY A 1 427 ? -2.937  14.142  50.733  1 37.965 ? 419  GLY A CA  1 
ATOM   3190 C  C   . GLY A 1 427 ? -4.233  13.712  50.022  1 35.373 ? 419  GLY A C   1 
ATOM   3191 O  O   . GLY A 1 427 ? -5.025  12.923  50.557  1 34.997 ? 419  GLY A O   1 
ATOM   3192 N  N   . ASN A 1 428 ? -4.406  14.198  48.784  1 33.6   ? 420  ASN A N   1 
ATOM   3193 C  CA  . ASN A 1 428 ? -5.6    13.943  47.972  1 35.616 ? 420  ASN A CA  1 
ATOM   3194 C  C   . ASN A 1 428 ? -5.569  12.578  47.283  1 31.317 ? 420  ASN A C   1 
ATOM   3195 O  O   . ASN A 1 428 ? -6.595  12.145  46.752  1 26.912 ? 420  ASN A O   1 
ATOM   3196 C  CB  . ASN A 1 428 ? -5.959  15.099  47.044  1 38.348 ? 420  ASN A CB  1 
ATOM   3197 C  CG  . ASN A 1 428 ? -6.636  16.228  47.795  1 44.424 ? 420  ASN A CG  1 
ATOM   3198 O  OD1 . ASN A 1 428 ? -7.091  16.06   48.94   1 45.407 ? 420  ASN A OD1 1 
ATOM   3199 N  ND2 . ASN A 1 428 ? -6.718  17.387  47.162  1 40.205 ? 420  ASN A ND2 1 
ATOM   3200 N  N   . LYS A 1 429 ? -4.373  11.952  47.256  1 27.546 ? 421  LYS A N   1 
ATOM   3201 C  CA  . LYS A 1 429 ? -4.15   10.689  46.545  1 26.474 ? 421  LYS A CA  1 
ATOM   3202 C  C   . LYS A 1 429 ? -4.773  9.54    47.327  1 22.824 ? 421  LYS A C   1 
ATOM   3203 O  O   . LYS A 1 429 ? -4.631  9.461   48.565  1 20.655 ? 421  LYS A O   1 
ATOM   3204 C  CB  . LYS A 1 429 ? -2.637  10.408  46.401  1 29.421 ? 421  LYS A CB  1 
ATOM   3205 C  CG  . LYS A 1 429 ? -1.796  11.271  45.465  1 31.877 ? 421  LYS A CG  1 
ATOM   3206 C  CD  . LYS A 1 429 ? -2.103  11.338  43.972  1 40.569 ? 421  LYS A CD  1 
ATOM   3207 C  CE  . LYS A 1 429 ? -1.874  10.168  43.095  1 43.439 ? 421  LYS A CE  1 
ATOM   3208 N  NZ  . LYS A 1 429 ? -1.389  10.667  41.808  1 53.298 ? 421  LYS A NZ  1 
ATOM   3209 N  N   . ASN A 1 430 ? -5.4    8.592   46.598  1 22.317 ? 422  ASN A N   1 
ATOM   3210 C  CA  . ASN A 1 430 ? -5.669  7.254   47.132  1 22.07  ? 422  ASN A CA  1 
ATOM   3211 C  C   . ASN A 1 430 ? -4.453  6.705   47.895  1 23.725 ? 422  ASN A C   1 
ATOM   3212 O  O   . ASN A 1 430 ? -3.302  6.968   47.519  1 24.706 ? 422  ASN A O   1 
ATOM   3213 C  CB  . ASN A 1 430 ? -6.188  6.357   46.006  1 23.597 ? 422  ASN A CB  1 
ATOM   3214 C  CG  . ASN A 1 430 ? -6.336  4.912   46.42   1 21.938 ? 422  ASN A CG  1 
ATOM   3215 O  OD1 . ASN A 1 430 ? -5.381  4.142   46.197  1 17.53  ? 422  ASN A OD1 1 
ATOM   3216 N  ND2 . ASN A 1 430 ? -7.476  4.54    47.012  1 22.311 ? 422  ASN A ND2 1 
ATOM   3217 N  N   . VAL A 1 431 ? -4.697  5.917   48.959  1 19.83  ? 423  VAL A N   1 
ATOM   3218 C  CA  . VAL A 1 431 ? -3.628  5.453   49.855  1 19.473 ? 423  VAL A CA  1 
ATOM   3219 C  C   . VAL A 1 431 ? -2.538  4.664   49.105  1 19.059 ? 423  VAL A C   1 
ATOM   3220 O  O   . VAL A 1 431 ? -1.376  4.706   49.518  1 18.085 ? 423  VAL A O   1 
ATOM   3221 C  CB  . VAL A 1 431 ? -4.196  4.665   51.061  1 20.462 ? 423  VAL A CB  1 
ATOM   3222 C  CG1 . VAL A 1 431 ? -4.78   3.317   50.637  1 20.695 ? 423  VAL A CG1 1 
ATOM   3223 C  CG2 . VAL A 1 431 ? -3.2    4.46    52.187  1 22.872 ? 423  VAL A CG2 1 
ATOM   3224 N  N   . PHE A 1 432 ? -2.903  4.005   47.983  1 17.88  ? 424  PHE A N   1 
ATOM   3225 C  CA  . PHE A 1 432 ? -1.935  3.182   47.25   1 18.255 ? 424  PHE A CA  1 
ATOM   3226 C  C   . PHE A 1 432 ? -1.09   4.004   46.277  1 20.881 ? 424  PHE A C   1 
ATOM   3227 O  O   . PHE A 1 432 ? -0.086  3.482   45.762  1 20.816 ? 424  PHE A O   1 
ATOM   3228 C  CB  . PHE A 1 432 ? -2.59   2.018   46.507  1 18.776 ? 424  PHE A CB  1 
ATOM   3229 C  CG  . PHE A 1 432 ? -3.24   1.051   47.489  1 16.752 ? 424  PHE A CG  1 
ATOM   3230 C  CD1 . PHE A 1 432 ? -2.445  0.241   48.316  1 20.118 ? 424  PHE A CD1 1 
ATOM   3231 C  CD2 . PHE A 1 432 ? -4.615  1.063   47.671  1 17.151 ? 424  PHE A CD2 1 
ATOM   3232 C  CE1 . PHE A 1 432 ? -3.003  -0.587  49.262  1 17.047 ? 424  PHE A CE1 1 
ATOM   3233 C  CE2 . PHE A 1 432 ? -5.201  0.2     48.595  1 18.221 ? 424  PHE A CE2 1 
ATOM   3234 C  CZ  . PHE A 1 432 ? -4.379  -0.648  49.37   1 17.131 ? 424  PHE A CZ  1 
ATOM   3235 N  N   . GLN A 1 433 ? -1.439  5.275   46.095  1 20.583 ? 425  GLN A N   1 
ATOM   3236 C  CA  . GLN A 1 433 ? -0.95   6.057   44.961  1 25.511 ? 425  GLN A CA  1 
ATOM   3237 C  C   . GLN A 1 433 ? -0.07   7.25    45.333  1 23.932 ? 425  GLN A C   1 
ATOM   3238 O  O   . GLN A 1 433 ? 0.537   7.849   44.43   1 21.224 ? 425  GLN A O   1 
ATOM   3239 C  CB  . GLN A 1 433 ? -2.153  6.495   44.124  1 26.639 ? 425  GLN A CB  1 
ATOM   3240 C  CG  . GLN A 1 433 ? -3.057  5.351   43.674  1 24.91  ? 425  GLN A CG  1 
ATOM   3241 C  CD  . GLN A 1 433 ? -4.055  5.777   42.628  1 27.485 ? 425  GLN A CD  1 
ATOM   3242 O  OE1 . GLN A 1 433 ? -4.301  6.965   42.398  1 30.479 ? 425  GLN A OE1 1 
ATOM   3243 N  NE2 . GLN A 1 433 ? -4.716  4.793   42.047  1 27.306 ? 425  GLN A NE2 1 
ATOM   3244 N  N   . GLY A 1 434 ? 0.082   7.6     46.615  1 22.103 ? 426  GLY A N   1 
ATOM   3245 C  CA  . GLY A 1 434 ? 1.033   8.647   46.967  1 24.498 ? 426  GLY A CA  1 
ATOM   3246 C  C   . GLY A 1 434 ? 2.114   8.241   47.985  1 24.719 ? 426  GLY A C   1 
ATOM   3247 O  O   . GLY A 1 434 ? 2.619   9.082   48.733  1 21.703 ? 426  GLY A O   1 
ATOM   3248 N  N   . LEU A 1 435 ? 2.471   6.956   48.044  1 20.698 ? 427  LEU A N   1 
ATOM   3249 C  CA  . LEU A 1 435 ? 3.398   6.406   49.024  1 20.318 ? 427  LEU A CA  1 
ATOM   3250 C  C   . LEU A 1 435 ? 4.838   6.743   48.6    1 21.118 ? 427  LEU A C   1 
ATOM   3251 O  O   . LEU A 1 435 ? 5.404   6.167   47.659  1 23.404 ? 427  LEU A O   1 
ATOM   3252 C  CB  . LEU A 1 435 ? 3.203   4.904   49.288  1 19.236 ? 427  LEU A CB  1 
ATOM   3253 C  CG  . LEU A 1 435 ? 1.82    4.501   49.816  1 18.087 ? 427  LEU A CG  1 
ATOM   3254 C  CD1 . LEU A 1 435 ? 1.56    3.064   49.448  1 15.5   ? 427  LEU A CD1 1 
ATOM   3255 C  CD2 . LEU A 1 435 ? 1.72    4.62    51.362  1 15.953 ? 427  LEU A CD2 1 
ATOM   3256 N  N   . ASN A 1 436 ? 5.409   7.721   49.294  1 19.607 ? 428  ASN A N   1 
ATOM   3257 C  CA  . ASN A 1 436 ? 6.666   8.281   48.805  1 22.89  ? 428  ASN A CA  1 
ATOM   3258 C  C   . ASN A 1 436 ? 7.742   8.23    49.884  1 23.515 ? 428  ASN A C   1 
ATOM   3259 O  O   . ASN A 1 436 ? 8.725   8.96    49.797  1 24.243 ? 428  ASN A O   1 
ATOM   3260 C  CB  . ASN A 1 436 ? 6.464   9.708   48.283  1 29.062 ? 428  ASN A CB  1 
ATOM   3261 C  CG  . ASN A 1 436 ? 6.025   10.731  49.325  1 26.249 ? 428  ASN A CG  1 
ATOM   3262 O  OD1 . ASN A 1 436 ? 5.568   10.424  50.434  1 20.413 ? 428  ASN A OD1 1 
ATOM   3263 N  ND2 . ASN A 1 436 ? 6.108   11.989  48.941  1 27.925 ? 428  ASN A ND2 1 
ATOM   3264 N  N   . GLY A 1 437 ? 7.527   7.448   50.944  1 17.785 ? 429  GLY A N   1 
ATOM   3265 C  CA  . GLY A 1 437 ? 8.557   7.283   51.947  1 18.124 ? 429  GLY A CA  1 
ATOM   3266 C  C   . GLY A 1 437 ? 8.42    5.973   52.71   1 20.075 ? 429  GLY A C   1 
ATOM   3267 O  O   . GLY A 1 437 ? 7.493   5.201   52.43   1 16.905 ? 429  GLY A O   1 
ATOM   3268 N  N   . LEU A 1 438 ? 9.317   5.786   53.69   1 14.647 ? 430  LEU A N   1 
ATOM   3269 C  CA  . LEU A 1 438 ? 9.166   4.667   54.618  1 12.298 ? 430  LEU A CA  1 
ATOM   3270 C  C   . LEU A 1 438 ? 9.284   5.258   56.011  1 15.251 ? 430  LEU A C   1 
ATOM   3271 O  O   . LEU A 1 438 ? 9.991   6.259   56.201  1 19.699 ? 430  LEU A O   1 
ATOM   3272 C  CB  . LEU A 1 438 ? 10.269  3.624   54.481  1 12.234 ? 430  LEU A CB  1 
ATOM   3273 C  CG  . LEU A 1 438 ? 10.571  3.119   53.073  1 13.218 ? 430  LEU A CG  1 
ATOM   3274 C  CD1 . LEU A 1 438 ? 11.823  2.298   52.979  1 14.101 ? 430  LEU A CD1 1 
ATOM   3275 C  CD2 . LEU A 1 438 ? 9.395   2.24    52.662  1 13.616 ? 430  LEU A CD2 1 
ATOM   3276 N  N   . ALA A 1 439 ? 8.748   4.517   56.97   1 15.309 ? 431  ALA A N   1 
ATOM   3277 C  CA  . ALA A 1 439 ? 8.911   4.83    58.393  1 16.146 ? 431  ALA A CA  1 
ATOM   3278 C  C   . ALA A 1 439 ? 9.437   3.611   59.123  1 18.099 ? 431  ALA A C   1 
ATOM   3279 O  O   . ALA A 1 439 ? 8.969   2.493   58.902  1 18.132 ? 431  ALA A O   1 
ATOM   3280 C  CB  . ALA A 1 439 ? 7.554   5.315   58.897  1 18.119 ? 431  ALA A CB  1 
ATOM   3281 N  N   . HIS A 1 440 ? 10.396  3.802   60.05   1 21.445 ? 432  HIS A N   1 
ATOM   3282 C  CA  . HIS A 1 440 ? 10.762  2.784   61.018  1 23.691 ? 432  HIS A CA  1 
ATOM   3283 C  C   . HIS A 1 440 ? 10.223  3.173   62.378  1 26.45  ? 432  HIS A C   1 
ATOM   3284 O  O   . HIS A 1 440 ? 10.791  4.065   62.977  1 23.013 ? 432  HIS A O   1 
ATOM   3285 C  CB  . HIS A 1 440 ? 12.273  2.484   61.12   1 19.241 ? 432  HIS A CB  1 
ATOM   3286 C  CG  . HIS A 1 440 ? 12.681  1.32    61.981  1 18.993 ? 432  HIS A CG  1 
ATOM   3287 N  ND1 . HIS A 1 440 ? 14.009  1.019   62.22   1 18.293 ? 432  HIS A ND1 1 
ATOM   3288 C  CD2 . HIS A 1 440 ? 11.984  0.364   62.651  1 18.965 ? 432  HIS A CD2 1 
ATOM   3289 C  CE1 . HIS A 1 440 ? 14.107  -0.061  62.935  1 18.267 ? 432  HIS A CE1 1 
ATOM   3290 N  NE2 . HIS A 1 440 ? 12.869  -0.442  63.265  1 20.481 ? 432  HIS A NE2 1 
ATOM   3291 N  N   . TYR A 1 441 ? 9.164   2.467   62.812  1 23.8   ? 433  TYR A N   1 
ATOM   3292 C  CA  . TYR A 1 441 ? 8.537   2.729   64.097  1 23.275 ? 433  TYR A CA  1 
ATOM   3293 C  C   . TYR A 1 441 ? 8.995   1.666   65.059  1 20.7   ? 433  TYR A C   1 
ATOM   3294 O  O   . TYR A 1 441 ? 9.056   0.499   64.697  1 23.776 ? 433  TYR A O   1 
ATOM   3295 C  CB  . TYR A 1 441 ? 7.015   2.747   63.959  1 28.722 ? 433  TYR A CB  1 
ATOM   3296 C  CG  . TYR A 1 441 ? 6.257   2.663   65.278  1 30.345 ? 433  TYR A CG  1 
ATOM   3297 C  CD1 . TYR A 1 441 ? 6.153   3.799   66.083  1 30.361 ? 433  TYR A CD1 1 
ATOM   3298 C  CD2 . TYR A 1 441 ? 5.638   1.481   65.708  1 26.159 ? 433  TYR A CD2 1 
ATOM   3299 C  CE1 . TYR A 1 441 ? 5.476   3.752   67.293  1 25.841 ? 433  TYR A CE1 1 
ATOM   3300 C  CE2 . TYR A 1 441 ? 4.94    1.443   66.902  1 24.415 ? 433  TYR A CE2 1 
ATOM   3301 C  CZ  . TYR A 1 441 ? 4.867   2.585   67.691  1 22.885 ? 433  TYR A CZ  1 
ATOM   3302 O  OH  . TYR A 1 441 ? 4.15    2.62    68.849  1 21.31  ? 433  TYR A OH  1 
ATOM   3303 N  N   . LYS A 1 442 ? 9.329   2.094   66.299  1 21.12  ? 434  LYS A N   1 
ATOM   3304 C  CA  . LYS A 1 442 ? 9.677   1.163   67.336  1 21.462 ? 434  LYS A CA  1 
ATOM   3305 C  C   . LYS A 1 442 ? 8.81    1.481   68.543  1 25.859 ? 434  LYS A C   1 
ATOM   3306 O  O   . LYS A 1 442 ? 9.008   2.527   69.16   1 23.369 ? 434  LYS A O   1 
ATOM   3307 C  CB  . LYS A 1 442 ? 11.137  1.414   67.737  1 25.641 ? 434  LYS A CB  1 
ATOM   3308 C  CG  . LYS A 1 442 ? 12.205  0.839   66.793  1 34.091 ? 434  LYS A CG  1 
ATOM   3309 C  CD  . LYS A 1 442 ? 13.548  1.406   67.213  1 28.662 ? 434  LYS A CD  1 
ATOM   3310 C  CE  . LYS A 1 442 ? 14.61   0.928   66.276  1 31.036 ? 434  LYS A CE  1 
ATOM   3311 N  NZ  . LYS A 1 442 ? 16.025  0.979   66.726  1 25.894 ? 434  LYS A NZ  1 
ATOM   3312 N  N   . ARG A 1 443 ? 7.871   0.575   68.836  1 22.802 ? 435  ARG A N   1 
ATOM   3313 C  CA  . ARG A 1 443 ? 6.886   0.742   69.887  1 21.36  ? 435  ARG A CA  1 
ATOM   3314 C  C   . ARG A 1 443 ? 7.592   0.891   71.24   1 21.982 ? 435  ARG A C   1 
ATOM   3315 O  O   . ARG A 1 443 ? 7.151   1.693   72.074  1 25.288 ? 435  ARG A O   1 
ATOM   3316 C  CB  . ARG A 1 443 ? 6.038   -0.545  70.017  1 20.553 ? 435  ARG A CB  1 
ATOM   3317 C  CG  . ARG A 1 443 ? 4.918   -0.439  71.047  1 18.894 ? 435  ARG A CG  1 
ATOM   3318 C  CD  . ARG A 1 443 ? 3.978   -1.684  71.054  1 19.692 ? 435  ARG A CD  1 
ATOM   3319 N  NE  . ARG A 1 443 ? 4.624   -2.997  71.169  1 18.939 ? 435  ARG A NE  1 
ATOM   3320 C  CZ  . ARG A 1 443 ? 5.264   -3.52   72.213  1 24.455 ? 435  ARG A CZ  1 
ATOM   3321 N  NH1 . ARG A 1 443 ? 5.147   -2.959  73.415  1 19.281 ? 435  ARG A NH1 1 
ATOM   3322 N  NH2 . ARG A 1 443 ? 6.003   -4.626  72.054  1 22.924 ? 435  ARG A NH2 1 
ATOM   3323 N  N   . LYS A 1 444 ? 8.634   0.095   71.471  1 19.17  ? 436  LYS A N   1 
ATOM   3324 C  CA  . LYS A 1 444 ? 9.219   0.094   72.824  1 28.837 ? 436  LYS A CA  1 
ATOM   3325 C  C   . LYS A 1 444 ? 9.88    1.433   73.173  1 28.881 ? 436  LYS A C   1 
ATOM   3326 O  O   . LYS A 1 444 ? 9.772   1.88    74.317  1 27.578 ? 436  LYS A O   1 
ATOM   3327 C  CB  . LYS A 1 444 ? 10.108  -1.137  73.009  1 27.364 ? 436  LYS A CB  1 
ATOM   3328 C  CG  . LYS A 1 444 ? 9.262   -2.374  73.307  1 23.056 ? 436  LYS A CG  1 
ATOM   3329 C  CD  . LYS A 1 444 ? 10.192  -3.537  73.075  1 22.925 ? 436  LYS A CD  1 
ATOM   3330 C  CE  . LYS A 1 444 ? 9.48    -4.773  73.4    1 26.165 ? 436  LYS A CE  1 
ATOM   3331 N  NZ  . LYS A 1 444 ? 10.541  -5.784  73.374  1 25.782 ? 436  LYS A NZ  1 
ATOM   3332 N  N   . GLU A 1 445 ? 10.602  2.02    72.21   1 25.913 ? 437  GLU A N   1 
ATOM   3333 C  CA  . GLU A 1 445 ? 11.224  3.347   72.308  1 27.79  ? 437  GLU A CA  1 
ATOM   3334 C  C   . GLU A 1 445 ? 10.231  4.466   72.018  1 35.322 ? 437  GLU A C   1 
ATOM   3335 O  O   . GLU A 1 445 ? 10.497  5.619   72.372  1 39.537 ? 437  GLU A O   1 
ATOM   3336 C  CB  . GLU A 1 445 ? 12.43   3.546   71.375  1 29.216 ? 437  GLU A CB  1 
ATOM   3337 C  CG  . GLU A 1 445 ? 13.581  2.57    71.65   1 36.462 ? 437  GLU A CG  1 
ATOM   3338 C  CD  . GLU A 1 445 ? 13.478  1.123   71.162  1 41.706 ? 437  GLU A CD  1 
ATOM   3339 O  OE1 . GLU A 1 445 ? 12.422  0.666   70.653  1 41.077 ? 437  GLU A OE1 1 
ATOM   3340 O  OE2 . GLU A 1 445 ? 14.48   0.423   71.306  1 40.223 ? 437  GLU A OE2 1 
ATOM   3341 N  N   . GLY A 1 446 ? 9.126   4.137   71.332  1 28.84  ? 438  GLY A N   1 
ATOM   3342 C  CA  . GLY A 1 446 ? 8.124   5.114   70.921  1 28.439 ? 438  GLY A CA  1 
ATOM   3343 C  C   . GLY A 1 446 ? 8.639   6.102   69.869  1 34.535 ? 438  GLY A C   1 
ATOM   3344 O  O   . GLY A 1 446 ? 8.068   7.197   69.746  1 35.012 ? 438  GLY A O   1 
ATOM   3345 N  N   . THR A 1 447 ? 9.676   5.705   69.094  1 28.063 ? 439  THR A N   1 
ATOM   3346 C  CA  . THR A 1 447 ? 10.261  6.593   68.094  1 26.698 ? 439  THR A CA  1 
ATOM   3347 C  C   . THR A 1 447 ? 9.881   6.141   66.679  1 21.525 ? 439  THR A C   1 
ATOM   3348 O  O   . THR A 1 447 ? 9.538   4.988   66.451  1 17.971 ? 439  THR A O   1 
ATOM   3349 C  CB  . THR A 1 447 ? 11.783  6.577   68.237  1 31.228 ? 439  THR A CB  1 
ATOM   3350 O  OG1 . THR A 1 447 ? 12.099  5.179   68.204  1 32.33  ? 439  THR A OG1 1 
ATOM   3351 C  CG2 . THR A 1 447 ? 12.288  7.442   69.39   1 30.697 ? 439  THR A CG2 1 
ATOM   3352 N  N   . THR A 1 448 ? 9.934   7.097   65.761  1 21.881 ? 440  THR A N   1 
ATOM   3353 C  CA  . THR A 1 448 ? 9.707   6.888   64.334  1 21.186 ? 440  THR A CA  1 
ATOM   3354 C  C   . THR A 1 448 ? 10.844  7.59    63.61   1 27.246 ? 440  THR A C   1 
ATOM   3355 O  O   . THR A 1 448 ? 11.189  8.735   63.945  1 27.342 ? 440  THR A O   1 
ATOM   3356 C  CB  . THR A 1 448 ? 8.34    7.442   63.906  1 21.864 ? 440  THR A CB  1 
ATOM   3357 O  OG1 . THR A 1 448 ? 7.439   6.723   64.724  1 23.395 ? 440  THR A OG1 1 
ATOM   3358 C  CG2 . THR A 1 448 ? 7.916   7.045   62.488  1 22.972 ? 440  THR A CG2 1 
ATOM   3359 N  N   . GLU A 1 449 ? 11.457  6.866   62.66   1 24.596 ? 441  GLU A N   1 
ATOM   3360 C  CA  . GLU A 1 449 ? 12.4    7.489   61.732  1 23.121 ? 441  GLU A CA  1 
ATOM   3361 C  C   . GLU A 1 449 ? 11.848  7.38    60.314  1 21.402 ? 441  GLU A C   1 
ATOM   3362 O  O   . GLU A 1 449 ? 10.966  6.55    60.061  1 19.468 ? 441  GLU A O   1 
ATOM   3363 C  CB  . GLU A 1 449 ? 13.734  6.782   61.892  1 27.225 ? 441  GLU A CB  1 
ATOM   3364 C  CG  . GLU A 1 449 ? 14.187  6.814   63.355  1 35.867 ? 441  GLU A CG  1 
ATOM   3365 C  CD  . GLU A 1 449 ? 15.244  5.812   63.661  1 35.647 ? 441  GLU A CD  1 
ATOM   3366 O  OE1 . GLU A 1 449 ? 16.31   6.172   63.175  1 39.421 ? 441  GLU A OE1 1 
ATOM   3367 O  OE2 . GLU A 1 449 ? 15.041  4.781   64.342  1 38.526 ? 441  GLU A OE2 1 
ATOM   3368 N  N   . TRP A 1 450 ? 12.357  8.233   59.413  1 20.576 ? 442  TRP A N   1 
ATOM   3369 C  CA  . TRP A 1 450 ? 11.675  8.474   58.154  1 21.696 ? 442  TRP A CA  1 
ATOM   3370 C  C   . TRP A 1 450 ? 12.681  8.448   57.024  1 21.472 ? 442  TRP A C   1 
ATOM   3371 O  O   . TRP A 1 450 ? 13.735  9.047   57.147  1 21.542 ? 442  TRP A O   1 
ATOM   3372 C  CB  . TRP A 1 450 ? 10.935  9.824   58.157  1 19.69  ? 442  TRP A CB  1 
ATOM   3373 C  CG  . TRP A 1 450 ? 9.919   9.992   59.262  1 23.621 ? 442  TRP A CG  1 
ATOM   3374 C  CD1 . TRP A 1 450 ? 10.184  10.336  60.562  1 28.435 ? 442  TRP A CD1 1 
ATOM   3375 C  CD2 . TRP A 1 450 ? 8.488   9.751   59.19   1 25.736 ? 442  TRP A CD2 1 
ATOM   3376 N  NE1 . TRP A 1 450 ? 9.029   10.364  61.302  1 31.14  ? 442  TRP A NE1 1 
ATOM   3377 C  CE2 . TRP A 1 450 ? 7.968   10.004  60.499  1 30.65  ? 442  TRP A CE2 1 
ATOM   3378 C  CE3 . TRP A 1 450 ? 7.597   9.343   58.178  1 22.502 ? 442  TRP A CE3 1 
ATOM   3379 C  CZ2 . TRP A 1 450 ? 6.606   9.854   60.805  1 27.625 ? 442  TRP A CZ2 1 
ATOM   3380 C  CZ3 . TRP A 1 450 ? 6.254   9.196   58.48   1 21.3   ? 442  TRP A CZ3 1 
ATOM   3381 C  CH2 . TRP A 1 450 ? 5.765   9.459   59.788  1 25.273 ? 442  TRP A CH2 1 
ATOM   3382 N  N   . TYR A 1 451 ? 12.26   7.856   55.906  1 21.557 ? 443  TYR A N   1 
ATOM   3383 C  CA  . TYR A 1 451 ? 13.067  7.808   54.681  1 23.973 ? 443  TYR A CA  1 
ATOM   3384 C  C   . TYR A 1 451 ? 12.187  8.435   53.593  1 23.253 ? 443  TYR A C   1 
ATOM   3385 O  O   . TYR A 1 451 ? 11.033  8.021   53.437  1 21.341 ? 443  TYR A O   1 
ATOM   3386 C  CB  . TYR A 1 451 ? 13.642  6.403   54.371  1 21.568 ? 443  TYR A CB  1 
ATOM   3387 C  CG  . TYR A 1 451 ? 14.348  6.438   53.013  1 19.262 ? 443  TYR A CG  1 
ATOM   3388 C  CD1 . TYR A 1 451 ? 15.682  6.893   52.904  1 16.872 ? 443  TYR A CD1 1 
ATOM   3389 C  CD2 . TYR A 1 451 ? 13.676  6.07    51.852  1 17.604 ? 443  TYR A CD2 1 
ATOM   3390 C  CE1 . TYR A 1 451 ? 16.285  7.016   51.663  1 19.027 ? 443  TYR A CE1 1 
ATOM   3391 C  CE2 . TYR A 1 451 ? 14.289  6.176   50.597  1 19.132 ? 443  TYR A CE2 1 
ATOM   3392 C  CZ  . TYR A 1 451 ? 15.607  6.631   50.512  1 21.082 ? 443  TYR A CZ  1 
ATOM   3393 O  OH  . TYR A 1 451 ? 16.228  6.8     49.293  1 20.951 ? 443  TYR A OH  1 
ATOM   3394 N  N   . TYR A 1 452 ? 12.703  9.452   52.861  1 21.828 ? 444  TYR A N   1 
ATOM   3395 C  CA  . TYR A 1 452 ? 11.929  10.067  51.79   1 24.131 ? 444  TYR A CA  1 
ATOM   3396 C  C   . TYR A 1 452 ? 12.465  9.522   50.473  1 21.823 ? 444  TYR A C   1 
ATOM   3397 O  O   . TYR A 1 452 ? 13.681  9.525   50.25   1 23.371 ? 444  TYR A O   1 
ATOM   3398 C  CB  . TYR A 1 452 ? 12.124  11.589  51.729  1 22.972 ? 444  TYR A CB  1 
ATOM   3399 C  CG  . TYR A 1 452 ? 11.52   12.387  50.584  1 20.837 ? 444  TYR A CG  1 
ATOM   3400 C  CD1 . TYR A 1 452 ? 10.164  12.357  50.31   1 22.343 ? 444  TYR A CD1 1 
ATOM   3401 C  CD2 . TYR A 1 452 ? 12.32   13.229  49.807  1 24.19  ? 444  TYR A CD2 1 
ATOM   3402 C  CE1 . TYR A 1 452 ? 9.614   13.131  49.306  1 24.131 ? 444  TYR A CE1 1 
ATOM   3403 C  CE2 . TYR A 1 452 ? 11.789  13.979  48.763  1 23.577 ? 444  TYR A CE2 1 
ATOM   3404 C  CZ  . TYR A 1 452 ? 10.425  13.937  48.532  1 27.736 ? 444  TYR A CZ  1 
ATOM   3405 O  OH  . TYR A 1 452 ? 9.823   14.657  47.558  1 25.982 ? 444  TYR A OH  1 
ATOM   3406 N  N   . ALA A 1 453 ? 11.55   9.048   49.617  1 24.103 ? 445  ALA A N   1 
ATOM   3407 C  CA  . ALA A 1 453 ? 11.952  8.417   48.357  1 26.515 ? 445  ALA A CA  1 
ATOM   3408 C  C   . ALA A 1 453 ? 12.602  9.424   47.415  1 21.741 ? 445  ALA A C   1 
ATOM   3409 O  O   . ALA A 1 453 ? 13.433  9.01    46.632  1 22.618 ? 445  ALA A O   1 
ATOM   3410 C  CB  . ALA A 1 453 ? 10.784  7.736   47.677  1 24.221 ? 445  ALA A CB  1 
ATOM   3411 N  N   . GLY A 1 454 ? 12.225  10.703  47.503  1 24.529 ? 446  GLY A N   1 
ATOM   3412 C  CA  . GLY A 1 454 ? 12.698  11.676  46.52   1 27.887 ? 446  GLY A CA  1 
ATOM   3413 C  C   . GLY A 1 454 ? 11.587  12.419  45.802  1 28.393 ? 446  GLY A C   1 
ATOM   3414 O  O   . GLY A 1 454 ? 10.447  11.949  45.819  1 27.551 ? 446  GLY A O   1 
ATOM   3415 N  N   . ASP A 1 455 ? 11.916  13.605  45.213  1 21.072 ? 447  ASP A N   1 
ATOM   3416 C  CA  . ASP A 1 455 ? 10.932  14.271  44.378  1 27.35  ? 447  ASP A CA  1 
ATOM   3417 C  C   . ASP A 1 455 ? 10.799  13.431  43.114  1 22.208 ? 447  ASP A C   1 
ATOM   3418 O  O   . ASP A 1 455 ? 11.805  12.921  42.633  1 25.89  ? 447  ASP A O   1 
ATOM   3419 C  CB  . ASP A 1 455 ? 11.323  15.693  43.941  1 28.761 ? 447  ASP A CB  1 
ATOM   3420 C  CG  . ASP A 1 455 ? 11.436  16.75   45.041  1 29.641 ? 447  ASP A CG  1 
ATOM   3421 O  OD1 . ASP A 1 455 ? 11.166  16.432  46.216  1 23.585 ? 447  ASP A OD1 1 
ATOM   3422 O  OD2 . ASP A 1 455 ? 11.822  17.883  44.712  1 30.941 ? 447  ASP A OD2 1 
ATOM   3423 N  N   . ASN A 1 456 ? 9.547   13.287  42.647  1 24.787 ? 448  ASN A N   1 
ATOM   3424 C  CA  . ASN A 1 456 ? 9.161   12.544  41.448  1 31.226 ? 448  ASN A CA  1 
ATOM   3425 C  C   . ASN A 1 456 ? 9.537   11.069  41.618  1 27.201 ? 448  ASN A C   1 
ATOM   3426 O  O   . ASN A 1 456 ? 9.965   10.424  40.666  1 26.547 ? 448  ASN A O   1 
ATOM   3427 C  CB  . ASN A 1 456 ? 9.688   13.182  40.165  1 35.4   ? 448  ASN A CB  1 
ATOM   3428 C  CG  . ASN A 1 456 ? 9.239   14.614  40.004  1 37.28  ? 448  ASN A CG  1 
ATOM   3429 O  OD1 . ASN A 1 456 ? 10.065  15.485  39.701  1 46.004 ? 448  ASN A OD1 1 
ATOM   3430 N  ND2 . ASN A 1 456 ? 7.939   14.879  40.095  1 42.971 ? 448  ASN A ND2 1 
ATOM   3431 N  N   . CYS A 1 457 ? 9.397   10.598  42.867  1 23.63  ? 449  CYS A N   1 
ATOM   3432 C  CA  . CYS A 1 457 ? 9.612   9.201   43.221  1 26.365 ? 449  CYS A CA  1 
ATOM   3433 C  C   . CYS A 1 457 ? 8.477   8.692   44.099  1 24.411 ? 449  CYS A C   1 
ATOM   3434 O  O   . CYS A 1 457 ? 7.826   9.432   44.869  1 21.148 ? 449  CYS A O   1 
ATOM   3435 C  CB  . CYS A 1 457 ? 10.907  8.951   43.998  1 23.362 ? 449  CYS A CB  1 
ATOM   3436 S  SG  . CYS A 1 457 ? 12.443  9.447   43.163  1 27.602 ? 449  CYS A SG  1 
ATOM   3437 N  N   . LEU A 1 458 ? 8.267   7.389   43.936  1 21.716 ? 450  LEU A N   1 
ATOM   3438 C  CA  . LEU A 1 458 ? 7.442   6.592   44.823  1 19.126 ? 450  LEU A CA  1 
ATOM   3439 C  C   . LEU A 1 458 ? 8.274   5.433   45.34   1 20.193 ? 450  LEU A C   1 
ATOM   3440 O  O   . LEU A 1 458 ? 9.264   5.038   44.76   1 20.992 ? 450  LEU A O   1 
ATOM   3441 C  CB  . LEU A 1 458 ? 6.128   6.147   44.178  1 20.21  ? 450  LEU A CB  1 
ATOM   3442 C  CG  . LEU A 1 458 ? 5.215   7.23    43.569  1 21.681 ? 450  LEU A CG  1 
ATOM   3443 C  CD1 . LEU A 1 458 ? 4.15    6.49    42.735  1 25.618 ? 450  LEU A CD1 1 
ATOM   3444 C  CD2 . LEU A 1 458 ? 4.496   8.201   44.545  1 21.709 ? 450  LEU A CD2 1 
ATOM   3445 N  N   . ILE A 1 459 ? 7.921   4.926   46.518  1 17.615 ? 451  ILE A N   1 
ATOM   3446 C  CA  . ILE A 1 459 ? 8.613   3.793   47.085  1 17.649 ? 451  ILE A CA  1 
ATOM   3447 C  C   . ILE A 1 459 ? 7.556   2.768   47.491  1 14.473 ? 451  ILE A C   1 
ATOM   3448 O  O   . ILE A 1 459 ? 6.467   3.147   47.914  1 17.141 ? 451  ILE A O   1 
ATOM   3449 C  CB  . ILE A 1 459 ? 9.514   4.214   48.272  1 18.92  ? 451  ILE A CB  1 
ATOM   3450 C  CG1 . ILE A 1 459 ? 10.539  3.159   48.615  1 20.55  ? 451  ILE A CG1 1 
ATOM   3451 C  CG2 . ILE A 1 459 ? 8.697   4.667   49.483  1 16.695 ? 451  ILE A CG2 1 
ATOM   3452 C  CD1 . ILE A 1 459 ? 11.753  3.681   49.379  1 21.989 ? 451  ILE A CD1 1 
ATOM   3453 N  N   . GLN A 1 460 ? 7.884   1.483   47.332  1 16.776 ? 452  GLN A N   1 
ATOM   3454 C  CA  . GLN A 1 460 ? 7.002   0.364   47.567  1 11.521 ? 452  GLN A CA  1 
ATOM   3455 C  C   . GLN A 1 460 ? 7.271   -0.202  48.941  1 12.345 ? 452  GLN A C   1 
ATOM   3456 O  O   . GLN A 1 460 ? 8.106   0.318   49.731  1 12.983 ? 452  GLN A O   1 
ATOM   3457 C  CB  . GLN A 1 460 ? 7.058   -0.581  46.36   1 12.7   ? 452  GLN A CB  1 
ATOM   3458 C  CG  . GLN A 1 460 ? 6.622   0.158   45.107  1 11.577 ? 452  GLN A CG  1 
ATOM   3459 C  CD  . GLN A 1 460 ? 6.973   -0.552  43.817  1 13     ? 452  GLN A CD  1 
ATOM   3460 O  OE1 . GLN A 1 460 ? 6.982   -1.793  43.701  1 13.734 ? 452  GLN A OE1 1 
ATOM   3461 N  NE2 . GLN A 1 460 ? 7.442   0.248   42.862  1 16.102 ? 452  GLN A NE2 1 
ATOM   3462 N  N   . GLU A 1 461 ? 6.597   -1.312  49.212  1 11.404 ? 453  GLU A N   1 
ATOM   3463 C  CA  . GLU A 1 461 ? 6.739   -2.012  50.501  1 11.828 ? 453  GLU A CA  1 
ATOM   3464 C  C   . GLU A 1 461 ? 8.208   -2.305  50.905  1 11.983 ? 453  GLU A C   1 
ATOM   3465 O  O   . GLU A 1 461 ? 9.034   -2.92   50.177  1 9.661  ? 453  GLU A O   1 
ATOM   3466 C  CB  . GLU A 1 461 ? 5.951   -3.331  50.439  1 10.087 ? 453  GLU A CB  1 
ATOM   3467 C  CG  . GLU A 1 461 ? 5.964   -4.066  51.809  1 11.76  ? 453  GLU A CG  1 
ATOM   3468 C  CD  . GLU A 1 461 ? 5.462   -5.463  51.535  1 15.554 ? 453  GLU A CD  1 
ATOM   3469 O  OE1 . GLU A 1 461 ? 5.913   -6.136  50.583  1 16.135 ? 453  GLU A OE1 1 
ATOM   3470 O  OE2 . GLU A 1 461 ? 4.542   -5.843  52.228  1 16.948 ? 453  GLU A OE2 1 
ATOM   3471 N  N   . PRO A 1 462 ? 8.558   -2.027  52.182  1 13.42  ? 454  PRO A N   1 
ATOM   3472 C  CA  . PRO A 1 462 ? 9.842   -2.413  52.741  1 15.156 ? 454  PRO A CA  1 
ATOM   3473 C  C   . PRO A 1 462 ? 9.926   -3.844  53.252  1 15.199 ? 454  PRO A C   1 
ATOM   3474 O  O   . PRO A 1 462 ? 8.894   -4.438  53.666  1 15.186 ? 454  PRO A O   1 
ATOM   3475 C  CB  . PRO A 1 462 ? 10.005  -1.38   53.913  1 17.842 ? 454  PRO A CB  1 
ATOM   3476 C  CG  . PRO A 1 462 ? 8.575   -1.297  54.391  1 16.406 ? 454  PRO A CG  1 
ATOM   3477 C  CD  . PRO A 1 462 ? 7.717   -1.295  53.17   1 14.806 ? 454  PRO A CD  1 
ATOM   3478 N  N   . VAL A 1 463 ? 11.148  -4.397  53.176  1 16.74  ? 455  VAL A N   1 
ATOM   3479 C  CA  . VAL A 1 463 ? 11.489  -5.685  53.763  1 16.16  ? 455  VAL A CA  1 
ATOM   3480 C  C   . VAL A 1 463 ? 12.76   -5.495  54.587  1 17.139 ? 455  VAL A C   1 
ATOM   3481 O  O   . VAL A 1 463 ? 13.624  -4.684  54.24   1 18.865 ? 455  VAL A O   1 
ATOM   3482 C  CB  . VAL A 1 463 ? 11.721  -6.82   52.775  1 21.175 ? 455  VAL A CB  1 
ATOM   3483 C  CG1 . VAL A 1 463 ? 10.44   -7.129  51.99   1 16.911 ? 455  VAL A CG1 1 
ATOM   3484 C  CG2 . VAL A 1 463 ? 12.857  -6.499  51.8    1 24.136 ? 455  VAL A CG2 1 
ATOM   3485 N  N   . PHE A 1 464 ? 12.801  -6.289  55.643  1 16.224 ? 456  PHE A N   1 
ATOM   3486 C  CA  . PHE A 1 464 ? 13.908  -6.26   56.606  1 18.54  ? 456  PHE A CA  1 
ATOM   3487 C  C   . PHE A 1 464 ? 14.753  -7.531  56.563  1 14.964 ? 456  PHE A C   1 
ATOM   3488 O  O   . PHE A 1 464 ? 14.255  -8.668  56.561  1 17.237 ? 456  PHE A O   1 
ATOM   3489 C  CB  . PHE A 1 464 ? 13.283  -6.077  57.989  1 16.016 ? 456  PHE A CB  1 
ATOM   3490 C  CG  . PHE A 1 464 ? 14.391  -6.063  59.057  1 21.378 ? 456  PHE A CG  1 
ATOM   3491 C  CD1 . PHE A 1 464 ? 15.234  -4.94   59.229  1 23.787 ? 456  PHE A CD1 1 
ATOM   3492 C  CD2 . PHE A 1 464 ? 14.578  -7.171  59.893  1 27.125 ? 456  PHE A CD2 1 
ATOM   3493 C  CE1 . PHE A 1 464 ? 16.2    -4.922  60.26   1 20.529 ? 456  PHE A CE1 1 
ATOM   3494 C  CE2 . PHE A 1 464 ? 15.554  -7.157  60.902  1 21.271 ? 456  PHE A CE2 1 
ATOM   3495 C  CZ  . PHE A 1 464 ? 16.368  -6.043  61.057  1 24.292 ? 456  PHE A CZ  1 
ATOM   3496 N  N   . SER A 1 465 ? 16.071  -7.338  56.583  1 17.391 ? 457  SER A N   1 
ATOM   3497 C  CA  . SER A 1 465 ? 17.038  -8.426  56.738  1 19.256 ? 457  SER A CA  1 
ATOM   3498 C  C   . SER A 1 465 ? 17.879  -8.13   57.989  1 22.529 ? 457  SER A C   1 
ATOM   3499 O  O   . SER A 1 465 ? 18.504  -7.066  58.037  1 18.551 ? 457  SER A O   1 
ATOM   3500 C  CB  . SER A 1 465 ? 17.95   -8.518  55.536  1 22.274 ? 457  SER A CB  1 
ATOM   3501 O  OG  . SER A 1 465 ? 18.996  -9.438  55.797  1 20.855 ? 457  SER A OG  1 
ATOM   3502 N  N   . PRO A 1 466 ? 17.959  -9.027  58.993  1 20.068 ? 458  PRO A N   1 
ATOM   3503 C  CA  . PRO A 1 466 ? 18.761  -8.695  60.168  1 22.464 ? 458  PRO A CA  1 
ATOM   3504 C  C   . PRO A 1 466 ? 20.267  -8.692  59.871  1 24.524 ? 458  PRO A C   1 
ATOM   3505 O  O   . PRO A 1 466 ? 20.735  -9.546  59.082  1 25.503 ? 458  PRO A O   1 
ATOM   3506 C  CB  . PRO A 1 466 ? 18.246  -9.655  61.243  1 23.807 ? 458  PRO A CB  1 
ATOM   3507 C  CG  . PRO A 1 466 ? 17.479  -10.753 60.532  1 26.943 ? 458  PRO A CG  1 
ATOM   3508 C  CD  . PRO A 1 466 ? 17.338  -10.372 59.053  1 23.305 ? 458  PRO A CD  1 
ATOM   3509 N  N   . ARG A 1 467 ? 21.015  -7.824  60.581  1 24.722 ? 459  ARG A N   1 
ATOM   3510 C  CA  . ARG A 1 467 ? 22.447  -7.595  60.417  1 27.94  ? 459  ARG A CA  1 
ATOM   3511 C  C   . ARG A 1 467 ? 23.226  -8.906  60.523  1 27.514 ? 459  ARG A C   1 
ATOM   3512 O  O   . ARG A 1 467 ? 24.128  -9.2    59.708  1 24.083 ? 459  ARG A O   1 
ATOM   3513 C  CB  . ARG A 1 467 ? 22.971  -6.521  61.386  1 27.133 ? 459  ARG A CB  1 
ATOM   3514 C  CG  . ARG A 1 467 ? 24.37   -5.999  61.047  1 26.711 ? 459  ARG A CG  1 
ATOM   3515 C  CD  . ARG A 1 467 ? 24.882  -4.945  62.009  1 23.758 ? 459  ARG A CD  1 
ATOM   3516 N  NE  . ARG A 1 467 ? 24.047  -3.752  62.109  1 23.026 ? 459  ARG A NE  1 
ATOM   3517 C  CZ  . ARG A 1 467 ? 23.749  -2.844  61.172  1 29.552 ? 459  ARG A CZ  1 
ATOM   3518 N  NH1 . ARG A 1 467 ? 24.53   -2.752  60.113  1 27.48  ? 459  ARG A NH1 1 
ATOM   3519 N  NH2 . ARG A 1 467 ? 22.728  -1.99   61.34   1 33.194 ? 459  ARG A NH2 1 
ATOM   3520 N  N   . SER A 1 468 ? 22.824  -9.7    61.517  1 28.099 ? 460  SER A N   1 
ATOM   3521 C  CA  . SER A 1 468 ? 23.264  -11.066 61.708  1 27.606 ? 460  SER A CA  1 
ATOM   3522 C  C   . SER A 1 468 ? 22.135  -11.777 62.432  1 24.739 ? 460  SER A C   1 
ATOM   3523 O  O   . SER A 1 468 ? 21.172  -11.124 62.86   1 24.527 ? 460  SER A O   1 
ATOM   3524 C  CB  . SER A 1 468 ? 24.55   -11.133 62.528  1 27.45  ? 460  SER A CB  1 
ATOM   3525 O  OG  . SER A 1 468 ? 24.283  -10.564 63.795  1 30.423 ? 460  SER A OG  1 
ATOM   3526 N  N   . LYS A 1 469 ? 22.285  -13.105 62.518  1 25.497 ? 461  LYS A N   1 
ATOM   3527 C  CA  . LYS A 1 469 ? 21.377  -14.008 63.2    1 31.406 ? 461  LYS A CA  1 
ATOM   3528 C  C   . LYS A 1 469 ? 20.956  -13.435 64.553  1 34.873 ? 461  LYS A C   1 
ATOM   3529 O  O   . LYS A 1 469 ? 19.761  -13.461 64.849  1 34.486 ? 461  LYS A O   1 
ATOM   3530 C  CB  . LYS A 1 469 ? 22.01   -15.4   63.291  1 38.524 ? 461  LYS A CB  1 
ATOM   3531 C  CG  . LYS A 1 469 ? 21.334  -16.501 64.118  1 38.064 ? 461  LYS A CG  1 
ATOM   3532 C  CD  . LYS A 1 469 ? 22.083  -17.833 64.227  1 40.538 ? 461  LYS A CD  1 
ATOM   3533 C  CE  . LYS A 1 469 ? 23.203  -17.916 65.236  1 53.901 ? 461  LYS A CE  1 
ATOM   3534 N  NZ  . LYS A 1 469 ? 22.784  -17.824 66.641  1 47.995 ? 461  LYS A NZ  1 
ATOM   3535 N  N   . ASP A 1 470 ? 21.934  -12.935 65.335  1 34.871 ? 462  ASP A N   1 
ATOM   3536 C  CA  . ASP A 1 470 ? 21.715  -12.579 66.737  1 33.292 ? 462  ASP A CA  1 
ATOM   3537 C  C   . ASP A 1 470 ? 21.642  -11.065 66.933  1 32.176 ? 462  ASP A C   1 
ATOM   3538 O  O   . ASP A 1 470 ? 21.744  -10.596 68.061  1 29.775 ? 462  ASP A O   1 
ATOM   3539 C  CB  . ASP A 1 470 ? 22.745  -13.216 67.659  1 39.094 ? 462  ASP A CB  1 
ATOM   3540 C  CG  . ASP A 1 470 ? 22.939  -14.725 67.562  1 45.198 ? 462  ASP A CG  1 
ATOM   3541 O  OD1 . ASP A 1 470 ? 21.911  -15.455 67.559  1 36.66  ? 462  ASP A OD1 1 
ATOM   3542 O  OD2 . ASP A 1 470 ? 24.125  -15.164 67.496  1 55.334 ? 462  ASP A OD2 1 
ATOM   3543 N  N   . ALA A 1 471 ? 21.486  -10.294 65.839  1 25.897 ? 463  ALA A N   1 
ATOM   3544 C  CA  . ALA A 1 471 ? 21.367  -8.837  65.942  1 21.626 ? 463  ALA A CA  1 
ATOM   3545 C  C   . ALA A 1 471 ? 20.116  -8.473  66.738  1 26.513 ? 463  ALA A C   1 
ATOM   3546 O  O   . ALA A 1 471 ? 19.157  -9.218  66.634  1 27.98  ? 463  ALA A O   1 
ATOM   3547 C  CB  . ALA A 1 471 ? 21.287  -8.21   64.569  1 17.433 ? 463  ALA A CB  1 
ATOM   3548 N  N   . PRO A 1 472 ? 20.074  -7.37   67.535  1 26.051 ? 464  PRO A N   1 
ATOM   3549 C  CA  . PRO A 1 472 ? 18.831  -6.877  68.128  1 24.183 ? 464  PRO A CA  1 
ATOM   3550 C  C   . PRO A 1 472 ? 17.689  -6.733  67.117  1 27.824 ? 464  PRO A C   1 
ATOM   3551 O  O   . PRO A 1 472 ? 17.922  -6.613  65.905  1 24.771 ? 464  PRO A O   1 
ATOM   3552 C  CB  . PRO A 1 472 ? 19.19   -5.465  68.537  1 25.787 ? 464  PRO A CB  1 
ATOM   3553 C  CG  . PRO A 1 472 ? 20.678  -5.564  68.869  1 29.567 ? 464  PRO A CG  1 
ATOM   3554 C  CD  . PRO A 1 472 ? 21.215  -6.474  67.825  1 26.394 ? 464  PRO A CD  1 
ATOM   3555 N  N   . GLU A 1 473 ? 16.463  -6.682  67.631  1 29.106 ? 465  GLU A N   1 
ATOM   3556 C  CA  . GLU A 1 473 ? 15.254  -6.499  66.824  1 26.439 ? 465  GLU A CA  1 
ATOM   3557 C  C   . GLU A 1 473 ? 15.312  -5.221  65.987  1 21.667 ? 465  GLU A C   1 
ATOM   3558 O  O   . GLU A 1 473 ? 15.515  -4.125  66.501  1 18.839 ? 465  GLU A O   1 
ATOM   3559 C  CB  . GLU A 1 473 ? 14      -6.43   67.693  1 27.197 ? 465  GLU A CB  1 
ATOM   3560 C  CG  . GLU A 1 473 ? 12.728  -6.361  66.833  1 23.755 ? 465  GLU A CG  1 
ATOM   3561 C  CD  . GLU A 1 473 ? 11.445  -6.359  67.632  1 25.641 ? 465  GLU A CD  1 
ATOM   3562 O  OE1 . GLU A 1 473 ? 11.523  -6.48   68.917  1 23.407 ? 465  GLU A OE1 1 
ATOM   3563 O  OE2 . GLU A 1 473 ? 10.413  -6.303  66.964  1 15.656 ? 465  GLU A OE2 1 
ATOM   3564 N  N   . GLY A 1 474 ? 15.163  -5.366  64.661  1 17.016 ? 466  GLY A N   1 
ATOM   3565 C  CA  . GLY A 1 474 ? 15.106  -4.225  63.798  1 18.176 ? 466  GLY A CA  1 
ATOM   3566 C  C   . GLY A 1 474 ? 16.476  -3.592  63.561  1 19.327 ? 466  GLY A C   1 
ATOM   3567 O  O   . GLY A 1 474 ? 16.534  -2.464  63.101  1 20.76  ? 466  GLY A O   1 
ATOM   3568 N  N   . ASP A 1 475 ? 17.536  -4.361  63.822  1 23.04  ? 467  ASP A N   1 
ATOM   3569 C  CA  . ASP A 1 475 ? 18.906  -3.979  63.526  1 24.584 ? 467  ASP A CA  1 
ATOM   3570 C  C   . ASP A 1 475 ? 19.335  -4.745  62.279  1 19.672 ? 467  ASP A C   1 
ATOM   3571 O  O   . ASP A 1 475 ? 19.426  -5.976  62.281  1 25.22  ? 467  ASP A O   1 
ATOM   3572 C  CB  . ASP A 1 475 ? 19.848  -4.084  64.716  1 23.855 ? 467  ASP A CB  1 
ATOM   3573 C  CG  . ASP A 1 475 ? 21.263  -3.611  64.37   1 22.098 ? 467  ASP A CG  1 
ATOM   3574 O  OD1 . ASP A 1 475 ? 21.459  -2.434  64.094  1 23.391 ? 467  ASP A OD1 1 
ATOM   3575 O  OD2 . ASP A 1 475 ? 22.152  -4.438  64.334  1 21.352 ? 467  ASP A OD2 1 
ATOM   3576 N  N   . GLY A 1 476 ? 19.533  -3.986  61.213  1 19.048 ? 468  GLY A N   1 
ATOM   3577 C  CA  . GLY A 1 476 ? 19.821  -4.586  59.929  1 18.717 ? 468  GLY A CA  1 
ATOM   3578 C  C   . GLY A 1 476 ? 19.578  -3.618  58.784  1 16.453 ? 468  GLY A C   1 
ATOM   3579 O  O   . GLY A 1 476 ? 19.87   -2.422  58.853  1 17.308 ? 468  GLY A O   1 
ATOM   3580 N  N   . PHE A 1 477 ? 19.124  -4.214  57.681  1 22.831 ? 469  PHE A N   1 
ATOM   3581 C  CA  . PHE A 1 477 ? 18.986  -3.523  56.414  1 18.459 ? 469  PHE A CA  1 
ATOM   3582 C  C   . PHE A 1 477 ? 17.525  -3.634  55.956  1 16.978 ? 469  PHE A C   1 
ATOM   3583 O  O   . PHE A 1 477 ? 16.913  -4.714  56.104  1 17.418 ? 469  PHE A O   1 
ATOM   3584 C  CB  . PHE A 1 477 ? 19.945  -4.189  55.422  1 21.487 ? 469  PHE A CB  1 
ATOM   3585 C  CG  . PHE A 1 477 ? 21.386  -4.024  55.936  1 21.926 ? 469  PHE A CG  1 
ATOM   3586 C  CD1 . PHE A 1 477 ? 22.042  -2.793  55.826  1 25.528 ? 469  PHE A CD1 1 
ATOM   3587 C  CD2 . PHE A 1 477 ? 22.04   -5.076  56.582  1 22.505 ? 469  PHE A CD2 1 
ATOM   3588 C  CE1 . PHE A 1 477 ? 23.347  -2.622  56.312  1 25.132 ? 469  PHE A CE1 1 
ATOM   3589 C  CE2 . PHE A 1 477 ? 23.354  -4.901  57.076  1 21.858 ? 469  PHE A CE2 1 
ATOM   3590 C  CZ  . PHE A 1 477 ? 23.995  -3.678  56.916  1 21.045 ? 469  PHE A CZ  1 
ATOM   3591 N  N   . VAL A 1 478 ? 17.032  -2.525  55.402  1 14.963 ? 470  VAL A N   1 
ATOM   3592 C  CA  . VAL A 1 478 ? 15.695  -2.428  54.842  1 13.123 ? 470  VAL A CA  1 
ATOM   3593 C  C   . VAL A 1 478 ? 15.915  -2.157  53.352  1 16.455 ? 470  VAL A C   1 
ATOM   3594 O  O   . VAL A 1 478 ? 16.691  -1.249  52.985  1 20.183 ? 470  VAL A O   1 
ATOM   3595 C  CB  . VAL A 1 478 ? 14.893  -1.295  55.522  1 15.316 ? 470  VAL A CB  1 
ATOM   3596 C  CG1 . VAL A 1 478 ? 13.567  -1.015  54.818  1 15.228 ? 470  VAL A CG1 1 
ATOM   3597 C  CG2 . VAL A 1 478 ? 14.586  -1.626  56.993  1 11.464 ? 470  VAL A CG2 1 
ATOM   3598 N  N   . LEU A 1 479 ? 15.188  -2.907  52.536  1 14.627 ? 471  LEU A N   1 
ATOM   3599 C  CA  . LEU A 1 479 ? 15.195  -2.809  51.084  1 12.709 ? 471  LEU A CA  1 
ATOM   3600 C  C   . LEU A 1 479 ? 13.787  -2.449  50.605  1 14.996 ? 471  LEU A C   1 
ATOM   3601 O  O   . LEU A 1 479 ? 12.779  -2.92   51.168  1 14.711 ? 471  LEU A O   1 
ATOM   3602 C  CB  . LEU A 1 479 ? 15.584  -4.197  50.567  1 12.572 ? 471  LEU A CB  1 
ATOM   3603 C  CG  . LEU A 1 479 ? 17.055  -4.614  50.722  1 19.636 ? 471  LEU A CG  1 
ATOM   3604 C  CD1 . LEU A 1 479 ? 17.373  -5.111  52.115  1 19.576 ? 471  LEU A CD1 1 
ATOM   3605 C  CD2 . LEU A 1 479 ? 17.139  -5.792  49.764  1 22.908 ? 471  LEU A CD2 1 
ATOM   3606 N  N   . ALA A 1 480 ? 13.696  -1.727  49.464  1 14.245 ? 472  ALA A N   1 
ATOM   3607 C  CA  . ALA A 1 480 ? 12.401  -1.456  48.847  1 12.099 ? 472  ALA A CA  1 
ATOM   3608 C  C   . ALA A 1 480 ? 12.654  -1.03   47.419  1 11.822 ? 472  ALA A C   1 
ATOM   3609 O  O   . ALA A 1 480 ? 13.704  -0.431  47.126  1 13.859 ? 472  ALA A O   1 
ATOM   3610 C  CB  . ALA A 1 480 ? 11.684  -0.287  49.519  1 10.793 ? 472  ALA A CB  1 
ATOM   3611 N  N   . ILE A 1 481 ? 11.611  -1.184  46.6    1 12.226 ? 473  ILE A N   1 
ATOM   3612 C  CA  . ILE A 1 481 ? 11.687  -0.751  45.207  1 11.181 ? 473  ILE A CA  1 
ATOM   3613 C  C   . ILE A 1 481 ? 11.288  0.741   45.162  1 13.184 ? 473  ILE A C   1 
ATOM   3614 O  O   . ILE A 1 481 ? 10.231  1.128   45.636  1 13.611 ? 473  ILE A O   1 
ATOM   3615 C  CB  . ILE A 1 481 ? 10.8    -1.594  44.275  1 11.57  ? 473  ILE A CB  1 
ATOM   3616 C  CG1 . ILE A 1 481 ? 11.102  -3.152  44.432  1 11.853 ? 473  ILE A CG1 1 
ATOM   3617 C  CG2 . ILE A 1 481 ? 11.054  -1.11   42.805  1 10.995 ? 473  ILE A CG2 1 
ATOM   3618 C  CD1 . ILE A 1 481 ? 12.611  -3.449  44.25   1 13.352 ? 473  ILE A CD1 1 
ATOM   3619 N  N   . VAL A 1 482 ? 12.078  1.543   44.456  1 13.718 ? 474  VAL A N   1 
ATOM   3620 C  CA  . VAL A 1 482 ? 11.807  2.945   44.191  1 13.838 ? 474  VAL A CA  1 
ATOM   3621 C  C   . VAL A 1 482 ? 11.498  3.109   42.706  1 16.515 ? 474  VAL A C   1 
ATOM   3622 O  O   . VAL A 1 482 ? 12.308  2.661   41.888  1 16.648 ? 474  VAL A O   1 
ATOM   3623 C  CB  . VAL A 1 482 ? 13.007  3.839   44.518  1 13.132 ? 474  VAL A CB  1 
ATOM   3624 C  CG1 . VAL A 1 482 ? 12.727  5.281   44.084  1 12.551 ? 474  VAL A CG1 1 
ATOM   3625 C  CG2 . VAL A 1 482 ? 13.289  3.814   46.02   1 15.687 ? 474  VAL A CG2 1 
ATOM   3626 N  N   . ASP A 1 483 ? 10.377  3.806   42.42   1 14.099 ? 475  ASP A N   1 
ATOM   3627 C  CA  . ASP A 1 483 ? 10.085  4.28    41.062  1 14.571 ? 475  ASP A CA  1 
ATOM   3628 C  C   . ASP A 1 483 ? 10.705  5.658   40.855  1 14.934 ? 475  ASP A C   1 
ATOM   3629 O  O   . ASP A 1 483 ? 10.246  6.592   41.487  1 17.194 ? 475  ASP A O   1 
ATOM   3630 C  CB  . ASP A 1 483 ? 8.584   4.404   40.852  1 17.639 ? 475  ASP A CB  1 
ATOM   3631 C  CG  . ASP A 1 483 ? 7.869   3.077   41.123  1 23.054 ? 475  ASP A CG  1 
ATOM   3632 O  OD1 . ASP A 1 483 ? 7.659   2.745   42.335  1 24.334 ? 475  ASP A OD1 1 
ATOM   3633 O  OD2 . ASP A 1 483 ? 7.647   2.376   40.137  1 21.695 ? 475  ASP A OD2 1 
ATOM   3634 N  N   . ARG A 1 484 ? 11.724  5.773   40.001  1 19.074 ? 476  ARG A N   1 
ATOM   3635 C  CA  . ARG A 1 484 ? 12.252  7.068   39.584  1 15.01  ? 476  ARG A CA  1 
ATOM   3636 C  C   . ARG A 1 484 ? 11.393  7.544   38.406  1 18.503 ? 476  ARG A C   1 
ATOM   3637 O  O   . ARG A 1 484 ? 11.661  7.192   37.244  1 16.751 ? 476  ARG A O   1 
ATOM   3638 C  CB  . ARG A 1 484 ? 13.702  6.761   39.207  1 19.709 ? 476  ARG A CB  1 
ATOM   3639 C  CG  . ARG A 1 484 ? 14.739  6.231   40.186  1 20.349 ? 476  ARG A CG  1 
ATOM   3640 C  CD  . ARG A 1 484 ? 14.859  7.051   41.44   1 19.613 ? 476  ARG A CD  1 
ATOM   3641 N  NE  . ARG A 1 484 ? 15.326  8.41    41.098  1 22.362 ? 476  ARG A NE  1 
ATOM   3642 C  CZ  . ARG A 1 484 ? 16.614  8.739   41.036  1 20.965 ? 476  ARG A CZ  1 
ATOM   3643 N  NH1 . ARG A 1 484 ? 17.539  7.885   41.392  1 19.429 ? 476  ARG A NH1 1 
ATOM   3644 N  NH2 . ARG A 1 484 ? 16.984  9.942   40.673  1 20.388 ? 476  ARG A NH2 1 
ATOM   3645 N  N   . LEU A 1 485 ? 10.314  8.306   38.701  1 18.128 ? 477  LEU A N   1 
ATOM   3646 C  CA  . LEU A 1 485 ? 9.259   8.517   37.711  1 24.205 ? 477  LEU A CA  1 
ATOM   3647 C  C   . LEU A 1 485 ? 9.731   9.374   36.529  1 23.454 ? 477  LEU A C   1 
ATOM   3648 O  O   . LEU A 1 485 ? 9.28    9.166   35.419  1 31.218 ? 477  LEU A O   1 
ATOM   3649 C  CB  . LEU A 1 485 ? 7.993   9.091   38.336  1 29.96  ? 477  LEU A CB  1 
ATOM   3650 C  CG  . LEU A 1 485 ? 7.375   8.331   39.516  1 32.014 ? 477  LEU A CG  1 
ATOM   3651 C  CD1 . LEU A 1 485 ? 6.326   9.266   40.179  1 29.985 ? 477  LEU A CD1 1 
ATOM   3652 C  CD2 . LEU A 1 485 ? 6.688   7.083   38.924  1 27.553 ? 477  LEU A CD2 1 
ATOM   3653 N  N   . ASP A 1 486 ? 10.656  10.291  36.77   1 27.022 ? 478  ASP A N   1 
ATOM   3654 C  CA  . ASP A 1 486 ? 11.26   11.117  35.719  1 36.779 ? 478  ASP A CA  1 
ATOM   3655 C  C   . ASP A 1 486 ? 12.32   10.37   34.877  1 37.363 ? 478  ASP A C   1 
ATOM   3656 O  O   . ASP A 1 486 ? 12.658  10.81   33.768  1 33.547 ? 478  ASP A O   1 
ATOM   3657 C  CB  . ASP A 1 486 ? 11.862  12.371  36.335  1 38.874 ? 478  ASP A CB  1 
ATOM   3658 C  CG  . ASP A 1 486 ? 12.94   12.116  37.378  1 44.475 ? 478  ASP A CG  1 
ATOM   3659 O  OD1 . ASP A 1 486 ? 13.05   10.969  37.868  1 55.632 ? 478  ASP A OD1 1 
ATOM   3660 O  OD2 . ASP A 1 486 ? 13.684  13.054  37.685  1 52.189 ? 478  ASP A OD2 1 
ATOM   3661 N  N   . LEU A 1 487 ? 12.834  9.227   35.373  1 35.406 ? 479  LEU A N   1 
ATOM   3662 C  CA  . LEU A 1 487 ? 13.871  8.473   34.656  1 29.371 ? 479  LEU A CA  1 
ATOM   3663 C  C   . LEU A 1 487 ? 13.357  7.22    33.948  1 28.382 ? 479  LEU A C   1 
ATOM   3664 O  O   . LEU A 1 487 ? 14.145  6.51    33.303  1 31.162 ? 479  LEU A O   1 
ATOM   3665 C  CB  . LEU A 1 487 ? 14.988  8.184   35.654  1 31.001 ? 479  LEU A CB  1 
ATOM   3666 C  CG  . LEU A 1 487 ? 15.729  9.412   36.193  1 32.523 ? 479  LEU A CG  1 
ATOM   3667 C  CD1 . LEU A 1 487 ? 16.685  9.101   37.319  1 27.132 ? 479  LEU A CD1 1 
ATOM   3668 C  CD2 . LEU A 1 487 ? 16.481  10.107  35.051  1 34.861 ? 479  LEU A CD2 1 
ATOM   3669 N  N   . ASN A 1 488 ? 12.063  6.902   34.102  1 23.371 ? 480  ASN A N   1 
ATOM   3670 C  CA  . ASN A 1 488 ? 11.496  5.641   33.624  1 23.888 ? 480  ASN A CA  1 
ATOM   3671 C  C   . ASN A 1 488 ? 12.361  4.444   34.024  1 15.447 ? 480  ASN A C   1 
ATOM   3672 O  O   . ASN A 1 488 ? 12.763  3.623   33.19   1 16.772 ? 480  ASN A O   1 
ATOM   3673 C  CB  . ASN A 1 488 ? 11.142  5.689   32.127  1 31.484 ? 480  ASN A CB  1 
ATOM   3674 C  CG  . ASN A 1 488 ? 10.27   4.535   31.629  1 41.779 ? 480  ASN A CG  1 
ATOM   3675 O  OD1 . ASN A 1 488 ? 9.379   4.023   32.328  1 40.785 ? 480  ASN A OD1 1 
ATOM   3676 N  ND2 . ASN A 1 488 ? 10.48   4.122   30.38   1 38.181 ? 480  ASN A ND2 1 
ATOM   3677 N  N   . ARG A 1 489 ? 12.688  4.327   35.323  1 12.483 ? 481  ARG A N   1 
ATOM   3678 C  CA  . ARG A 1 489 ? 13.383  3.114   35.72   1 12.11  ? 481  ARG A CA  1 
ATOM   3679 C  C   . ARG A 1 489 ? 13.033  2.867   37.195  1 13.364 ? 481  ARG A C   1 
ATOM   3680 O  O   . ARG A 1 489 ? 12.43   3.722   37.843  1 15.446 ? 481  ARG A O   1 
ATOM   3681 C  CB  . ARG A 1 489 ? 14.91   3.269   35.516  1 15.589 ? 481  ARG A CB  1 
ATOM   3682 C  CG  . ARG A 1 489 ? 15.634  4.076   36.608  1 16.039 ? 481  ARG A CG  1 
ATOM   3683 C  CD  . ARG A 1 489 ? 17.135  4.053   36.416  1 19.534 ? 481  ARG A CD  1 
ATOM   3684 N  NE  . ARG A 1 489 ? 17.812  4.818   37.475  1 25.155 ? 481  ARG A NE  1 
ATOM   3685 C  CZ  . ARG A 1 489 ? 18.636  5.782   37.158  1 26.621 ? 481  ARG A CZ  1 
ATOM   3686 N  NH1 . ARG A 1 489 ? 18.807  6.133   35.873  1 25.581 ? 481  ARG A NH1 1 
ATOM   3687 N  NH2 . ARG A 1 489 ? 19.371  6.294   38.109  1 28.933 ? 481  ARG A NH2 1 
ATOM   3688 N  N   . SER A 1 490 ? 13.322  1.658   37.652  1 13.581 ? 482  SER A N   1 
ATOM   3689 C  CA  . SER A 1 490 ? 13.064  1.299   39.035  1 13.57  ? 482  SER A CA  1 
ATOM   3690 C  C   . SER A 1 490 ? 14.388  0.974   39.669  1 13     ? 482  SER A C   1 
ATOM   3691 O  O   . SER A 1 490 ? 15.305  0.535   38.973  1 14.174 ? 482  SER A O   1 
ATOM   3692 C  CB  . SER A 1 490 ? 12.13   0.112   39.111  1 13.27  ? 482  SER A CB  1 
ATOM   3693 O  OG  . SER A 1 490 ? 10.909  0.392   38.438  1 11.117 ? 482  SER A OG  1 
ATOM   3694 N  N   . GLU A 1 491 ? 14.456  1.056   41.026  1 13.571 ? 483  GLU A N   1 
ATOM   3695 C  CA  . GLU A 1 491 ? 15.707  0.754   41.653  1 15.419 ? 483  GLU A CA  1 
ATOM   3696 C  C   . GLU A 1 491 ? 15.38   0.075   42.975  1 14.512 ? 483  GLU A C   1 
ATOM   3697 O  O   . GLU A 1 491 ? 14.256  0.205   43.42   1 17.722 ? 483  GLU A O   1 
ATOM   3698 C  CB  . GLU A 1 491 ? 16.414  2.073   42.063  1 19.246 ? 483  GLU A CB  1 
ATOM   3699 C  CG  . GLU A 1 491 ? 16.817  2.934   40.883  1 20.694 ? 483  GLU A CG  1 
ATOM   3700 C  CD  . GLU A 1 491 ? 17.518  4.254   41.129  1 22.165 ? 483  GLU A CD  1 
ATOM   3701 O  OE1 . GLU A 1 491 ? 17.546  4.796   42.266  1 19.972 ? 483  GLU A OE1 1 
ATOM   3702 O  OE2 . GLU A 1 491 ? 18.077  4.663   40.118  1 23.591 ? 483  GLU A OE2 1 
ATOM   3703 N  N   . VAL A 1 492 ? 16.359  -0.586  43.579  1 15.242 ? 484  VAL A N   1 
ATOM   3704 C  CA  . VAL A 1 492 ? 16.207  -1.145  44.919  1 13.838 ? 484  VAL A CA  1 
ATOM   3705 C  C   . VAL A 1 492 ? 17.094  -0.327  45.834  1 16.657 ? 484  VAL A C   1 
ATOM   3706 O  O   . VAL A 1 492 ? 18.267  -0.17   45.58   1 17.8   ? 484  VAL A O   1 
ATOM   3707 C  CB  . VAL A 1 492 ? 16.552  -2.647  45.034  1 13.725 ? 484  VAL A CB  1 
ATOM   3708 C  CG1 . VAL A 1 492 ? 16.111  -3.261  46.39   1 13.703 ? 484  VAL A CG1 1 
ATOM   3709 C  CG2 . VAL A 1 492 ? 16.078  -3.455  43.815  1 15.648 ? 484  VAL A CG2 1 
ATOM   3710 N  N   . VAL A 1 493 ? 16.509  0.25    46.868  1 18.153 ? 485  VAL A N   1 
ATOM   3711 C  CA  . VAL A 1 493 ? 17.295  1.018   47.815  1 19.884 ? 485  VAL A CA  1 
ATOM   3712 C  C   . VAL A 1 493 ? 17.545  0.094   48.976  1 17.237 ? 485  VAL A C   1 
ATOM   3713 O  O   . VAL A 1 493 ? 16.73   -0.776  49.234  1 15.787 ? 485  VAL A O   1 
ATOM   3714 C  CB  . VAL A 1 493 ? 16.581  2.33    48.215  1 19.962 ? 485  VAL A CB  1 
ATOM   3715 C  CG1 . VAL A 1 493 ? 15.242  2.162   48.951  1 19.109 ? 485  VAL A CG1 1 
ATOM   3716 C  CG2 . VAL A 1 493 ? 17.449  3.295   48.999  1 25.854 ? 485  VAL A CG2 1 
ATOM   3717 N  N   . VAL A 1 494 ? 18.716  0.291   49.594  1 16.239 ? 486  VAL A N   1 
ATOM   3718 C  CA  . VAL A 1 494 ? 19.162  -0.445  50.748  1 17.897 ? 486  VAL A CA  1 
ATOM   3719 C  C   . VAL A 1 494 ? 19.517  0.589   51.797  1 16.016 ? 486  VAL A C   1 
ATOM   3720 O  O   . VAL A 1 494 ? 20.282  1.552   51.536  1 15.514 ? 486  VAL A O   1 
ATOM   3721 C  CB  . VAL A 1 494 ? 20.378  -1.289  50.356  1 20.018 ? 486  VAL A CB  1 
ATOM   3722 C  CG1 . VAL A 1 494 ? 20.829  -2.224  51.489  1 19.587 ? 486  VAL A CG1 1 
ATOM   3723 C  CG2 . VAL A 1 494 ? 20.103  -2.114  49.095  1 21.826 ? 486  VAL A CG2 1 
ATOM   3724 N  N   . ILE A 1 495 ? 19.001  0.362   52.998  1 18.769 ? 487  ILE A N   1 
ATOM   3725 C  CA  . ILE A 1 495 ? 19.112  1.379   54.036  1 18.942 ? 487  ILE A CA  1 
ATOM   3726 C  C   . ILE A 1 495 ? 19.534  0.636   55.292  1 19.198 ? 487  ILE A C   1 
ATOM   3727 O  O   . ILE A 1 495 ? 18.974  -0.385  55.637  1 17.273 ? 487  ILE A O   1 
ATOM   3728 C  CB  . ILE A 1 495 ? 17.754  2.115   54.248  1 19.19  ? 487  ILE A CB  1 
ATOM   3729 C  CG1 . ILE A 1 495 ? 17.258  2.911   53.065  1 16.198 ? 487  ILE A CG1 1 
ATOM   3730 C  CG2 . ILE A 1 495 ? 17.691  2.934   55.554  1 19.13  ? 487  ILE A CG2 1 
ATOM   3731 C  CD1 . ILE A 1 495 ? 15.745  3.161   53.074  1 19.326 ? 487  ILE A CD1 1 
ATOM   3732 N  N   . ASP A 1 496 ? 20.5    1.206   55.993  1 21.134 ? 488  ASP A N   1 
ATOM   3733 C  CA  . ASP A 1 496 ? 20.951  0.64    57.26   1 21.181 ? 488  ASP A CA  1 
ATOM   3734 C  C   . ASP A 1 496 ? 20.107  1.27    58.37   1 17.436 ? 488  ASP A C   1 
ATOM   3735 O  O   . ASP A 1 496 ? 20.001  2.466   58.431  1 18.471 ? 488  ASP A O   1 
ATOM   3736 C  CB  . ASP A 1 496 ? 22.441  0.92    57.425  1 19.939 ? 488  ASP A CB  1 
ATOM   3737 C  CG  . ASP A 1 496 ? 23.117  0.231   58.589  1 21.791 ? 488  ASP A CG  1 
ATOM   3738 O  OD1 . ASP A 1 496 ? 22.531  0.299   59.688  1 20.039 ? 488  ASP A OD1 1 
ATOM   3739 O  OD2 . ASP A 1 496 ? 24.231  -0.341  58.38   1 23.895 ? 488  ASP A OD2 1 
ATOM   3740 N  N   . THR A 1 497 ? 19.516  0.458   59.251  1 20.572 ? 489  THR A N   1 
ATOM   3741 C  CA  . THR A 1 497 ? 18.666  0.972   60.339  1 23.304 ? 489  THR A CA  1 
ATOM   3742 C  C   . THR A 1 497 ? 19.451  1.878   61.307  1 29.301 ? 489  THR A C   1 
ATOM   3743 O  O   . THR A 1 497 ? 18.873  2.617   62.088  1 28.865 ? 489  THR A O   1 
ATOM   3744 C  CB  . THR A 1 497 ? 18.006  -0.169  61.115  1 23.072 ? 489  THR A CB  1 
ATOM   3745 O  OG1 . THR A 1 497 ? 19.08   -0.973  61.629  1 22.548 ? 489  THR A OG1 1 
ATOM   3746 C  CG2 . THR A 1 497 ? 17.021  -0.955  60.257  1 22.964 ? 489  THR A CG2 1 
ATOM   3747 N  N   . ARG A 1 498 ? 20.768  1.854   61.252  1 25.822 ? 490  ARG A N   1 
ATOM   3748 C  CA  . ARG A 1 498 ? 21.542  2.756   62.104  1 31.562 ? 490  ARG A CA  1 
ATOM   3749 C  C   . ARG A 1 498 ? 21.447  4.186   61.589  1 28.728 ? 490  ARG A C   1 
ATOM   3750 O  O   . ARG A 1 498 ? 21.547  5.127   62.369  1 28.886 ? 490  ARG A O   1 
ATOM   3751 C  CB  . ARG A 1 498 ? 22.958  2.238   62.347  1 29.952 ? 490  ARG A CB  1 
ATOM   3752 C  CG  . ARG A 1 498 ? 23.189  0.917   63.069  1 33.073 ? 490  ARG A CG  1 
ATOM   3753 C  CD  . ARG A 1 498 ? 24.63   0.603   62.721  1 34.624 ? 490  ARG A CD  1 
ATOM   3754 N  NE  . ARG A 1 498 ? 25.12   -0.712  63.159  1 38.664 ? 490  ARG A NE  1 
ATOM   3755 C  CZ  . ARG A 1 498 ? 26.326  -1.241  62.896  1 40.094 ? 490  ARG A CZ  1 
ATOM   3756 N  NH1 . ARG A 1 498 ? 27.191  -0.607  62.11   1 39.632 ? 490  ARG A NH1 1 
ATOM   3757 N  NH2 . ARG A 1 498 ? 26.661  -2.404  63.443  1 39.087 ? 490  ARG A NH2 1 
ATOM   3758 N  N   . ASP A 1 499 ? 21.165  4.359   60.289  1 30.35  ? 491  ASP A N   1 
ATOM   3759 C  CA  . ASP A 1 499 ? 20.724  5.662   59.843  1 29.058 ? 491  ASP A CA  1 
ATOM   3760 C  C   . ASP A 1 499 ? 19.598  5.55    58.81   1 29.575 ? 491  ASP A C   1 
ATOM   3761 O  O   . ASP A 1 499 ? 19.86   5.542   57.606  1 30.204 ? 491  ASP A O   1 
ATOM   3762 C  CB  . ASP A 1 499 ? 21.893  6.527   59.398  1 28.892 ? 491  ASP A CB  1 
ATOM   3763 C  CG  . ASP A 1 499 ? 21.479  7.923   58.959  1 25.009 ? 491  ASP A CG  1 
ATOM   3764 O  OD1 . ASP A 1 499 ? 20.32   8.323   59.167  1 31.382 ? 491  ASP A OD1 1 
ATOM   3765 O  OD2 . ASP A 1 499 ? 22.325  8.628   58.431  1 27.149 ? 491  ASP A OD2 1 
ATOM   3766 N  N   . PHE A 1 500 ? 18.349  5.583   59.295  1 30.273 ? 492  PHE A N   1 
ATOM   3767 C  CA  . PHE A 1 500 ? 17.184  5.246   58.466  1 24.997 ? 492  PHE A CA  1 
ATOM   3768 C  C   . PHE A 1 500 ? 16.886  6.301   57.403  1 30.552 ? 492  PHE A C   1 
ATOM   3769 O  O   . PHE A 1 500 ? 16.235  5.972   56.381  1 25.658 ? 492  PHE A O   1 
ATOM   3770 C  CB  . PHE A 1 500 ? 15.98   4.952   59.36   1 25.061 ? 492  PHE A CB  1 
ATOM   3771 C  CG  . PHE A 1 500 ? 14.862  4.248   58.602  1 24.596 ? 492  PHE A CG  1 
ATOM   3772 C  CD1 . PHE A 1 500 ? 14.986  2.894   58.262  1 29.871 ? 492  PHE A CD1 1 
ATOM   3773 C  CD2 . PHE A 1 500 ? 13.723  4.96    58.19   1 24.073 ? 492  PHE A CD2 1 
ATOM   3774 C  CE1 . PHE A 1 500 ? 13.976  2.235   57.544  1 25.021 ? 492  PHE A CE1 1 
ATOM   3775 C  CE2 . PHE A 1 500 ? 12.699  4.31    57.488  1 21.548 ? 492  PHE A CE2 1 
ATOM   3776 C  CZ  . PHE A 1 500 ? 12.832  2.958   57.179  1 23.349 ? 492  PHE A CZ  1 
ATOM   3777 N  N   . THR A 1 501 ? 17.416  7.533   57.607  1 22.964 ? 493  THR A N   1 
ATOM   3778 C  CA  . THR A 1 501 ? 17.178  8.649   56.717  1 22.325 ? 493  THR A CA  1 
ATOM   3779 C  C   . THR A 1 501 ? 17.919  8.543   55.384  1 22.619 ? 493  THR A C   1 
ATOM   3780 O  O   . THR A 1 501 ? 17.569  9.279   54.459  1 27.91  ? 493  THR A O   1 
ATOM   3781 C  CB  . THR A 1 501 ? 17.353  9.984   57.451  1 27.815 ? 493  THR A CB  1 
ATOM   3782 O  OG1 . THR A 1 501 ? 18.721  10.29   57.298  1 26.516 ? 493  THR A OG1 1 
ATOM   3783 C  CG2 . THR A 1 501 ? 16.875  9.941   58.896  1 28.023 ? 493  THR A CG2 1 
ATOM   3784 N  N   . LYS A 1 502 ? 18.904  7.639   55.293  1 27.936 ? 494  LYS A N   1 
ATOM   3785 C  CA  . LYS A 1 502 ? 19.88   7.627   54.201  1 31.999 ? 494  LYS A CA  1 
ATOM   3786 C  C   . LYS A 1 502 ? 20      6.243   53.567  1 26.78  ? 494  LYS A C   1 
ATOM   3787 O  O   . LYS A 1 502 ? 20.242  5.246   54.257  1 30.437 ? 494  LYS A O   1 
ATOM   3788 C  CB  . LYS A 1 502 ? 21.236  8.031   54.807  1 36.344 ? 494  LYS A CB  1 
ATOM   3789 C  CG  . LYS A 1 502 ? 22.408  8.287   53.883  1 40.143 ? 494  LYS A CG  1 
ATOM   3790 C  CD  . LYS A 1 502 ? 22.69   9.764   53.643  1 43.019 ? 494  LYS A CD  1 
ATOM   3791 C  CE  . LYS A 1 502 ? 24.047  9.961   53.01   1 43.166 ? 494  LYS A CE  1 
ATOM   3792 N  NZ  . LYS A 1 502 ? 25.216  9.754   53.88   1 39.37  ? 494  LYS A NZ  1 
ATOM   3793 N  N   . ALA A 1 503 ? 19.973  6.19    52.218  1 24.382 ? 495  ALA A N   1 
ATOM   3794 C  CA  . ALA A 1 503 ? 20.352  4.974   51.523  1 20.829 ? 495  ALA A CA  1 
ATOM   3795 C  C   . ALA A 1 503 ? 21.856  4.728   51.544  1 24.288 ? 495  ALA A C   1 
ATOM   3796 O  O   . ALA A 1 503 ? 22.61   5.648   51.224  1 26.855 ? 495  ALA A O   1 
ATOM   3797 C  CB  . ALA A 1 503 ? 19.925  5.12    50.065  1 20.905 ? 495  ALA A CB  1 
ATOM   3798 N  N   . VAL A 1 504 ? 22.271  3.477   51.831  1 21.019 ? 496  VAL A N   1 
ATOM   3799 C  CA  . VAL A 1 504 ? 23.651  3.038   51.68   1 25.613 ? 496  VAL A CA  1 
ATOM   3800 C  C   . VAL A 1 504 ? 23.925  2.679   50.218  1 29.108 ? 496  VAL A C   1 
ATOM   3801 O  O   . VAL A 1 504 ? 25.016  2.929   49.684  1 26.491 ? 496  VAL A O   1 
ATOM   3802 C  CB  . VAL A 1 504 ? 24.136  1.958   52.653  1 25.498 ? 496  VAL A CB  1 
ATOM   3803 C  CG1 . VAL A 1 504 ? 24.108  2.515   54.072  1 24.6   ? 496  VAL A CG1 1 
ATOM   3804 C  CG2 . VAL A 1 504 ? 23.418  0.612   52.578  1 25.197 ? 496  VAL A CG2 1 
ATOM   3805 N  N   . ALA A 1 505 ? 22.92   2.094   49.567  1 23.758 ? 497  ALA A N   1 
ATOM   3806 C  CA  . ALA A 1 505 ? 23.149  1.586   48.222  1 18.983 ? 497  ALA A CA  1 
ATOM   3807 C  C   . ALA A 1 505 ? 21.887  1.689   47.402  1 20.185 ? 497  ALA A C   1 
ATOM   3808 O  O   . ALA A 1 505 ? 20.8    1.731   47.971  1 16.494 ? 497  ALA A O   1 
ATOM   3809 C  CB  . ALA A 1 505 ? 23.683  0.171   48.258  1 21.02  ? 497  ALA A CB  1 
ATOM   3810 N  N   . ALA A 1 506 ? 22.055  1.701   46.053  1 18.714 ? 498  ALA A N   1 
ATOM   3811 C  CA  . ALA A 1 506 ? 20.915  1.686   45.16   1 18.697 ? 498  ALA A CA  1 
ATOM   3812 C  C   . ALA A 1 506 ? 21.205  0.695   44.03   1 20.538 ? 498  ALA A C   1 
ATOM   3813 O  O   . ALA A 1 506 ? 22.257  0.815   43.43   1 20.18  ? 498  ALA A O   1 
ATOM   3814 C  CB  . ALA A 1 506 ? 20.606  3.076   44.617  1 19.56  ? 498  ALA A CB  1 
ATOM   3815 N  N   . VAL A 1 507 ? 20.379  -0.375  43.904  1 14.474 ? 499  VAL A N   1 
ATOM   3816 C  CA  . VAL A 1 507 ? 20.51   -1.291  42.794  1 15.584 ? 499  VAL A CA  1 
ATOM   3817 C  C   . VAL A 1 507 ? 19.759  -0.651  41.627  1 14.684 ? 499  VAL A C   1 
ATOM   3818 O  O   . VAL A 1 507 ? 18.516  -0.448  41.696  1 18.307 ? 499  VAL A O   1 
ATOM   3819 C  CB  . VAL A 1 507 ? 19.934  -2.67   43.199  1 14.332 ? 499  VAL A CB  1 
ATOM   3820 C  CG1 . VAL A 1 507 ? 20.102  -3.669  42.057  1 15.155 ? 499  VAL A CG1 1 
ATOM   3821 C  CG2 . VAL A 1 507 ? 20.615  -3.305  44.401  1 15.675 ? 499  VAL A CG2 1 
ATOM   3822 N  N   . GLN A 1 508 ? 20.439  -0.476  40.49   1 12.899 ? 500  GLN A N   1 
ATOM   3823 C  CA  . GLN A 1 508 ? 19.911  0.382   39.447  1 14.402 ? 500  GLN A CA  1 
ATOM   3824 C  C   . GLN A 1 508 ? 19.553  -0.506  38.268  1 14.19  ? 500  GLN A C   1 
ATOM   3825 O  O   . GLN A 1 508 ? 20.433  -0.91   37.549  1 13.075 ? 500  GLN A O   1 
ATOM   3826 C  CB  . GLN A 1 508 ? 20.979  1.429   39.095  1 13.939 ? 500  GLN A CB  1 
ATOM   3827 C  CG  . GLN A 1 508 ? 20.565  2.448   38.036  1 17.907 ? 500  GLN A CG  1 
ATOM   3828 C  CD  . GLN A 1 508 ? 21.671  3.425   37.67   1 19.592 ? 500  GLN A CD  1 
ATOM   3829 O  OE1 . GLN A 1 508 ? 22.474  3.829   38.521  1 17.11  ? 500  GLN A OE1 1 
ATOM   3830 N  NE2 . GLN A 1 508 ? 21.755  3.78    36.39   1 16.447 ? 500  GLN A NE2 1 
ATOM   3831 N  N   . LEU A 1 509 ? 18.243  -0.756  38.052  1 12.24  ? 501  LEU A N   1 
ATOM   3832 C  CA  . LEU A 1 509 ? 17.827  -1.435  36.839  1 10.84  ? 501  LEU A CA  1 
ATOM   3833 C  C   . LEU A 1 509 ? 17.997  -0.509  35.641  1 10.591 ? 501  LEU A C   1 
ATOM   3834 O  O   . LEU A 1 509 ? 17.864  0.727   35.736  1 12.274 ? 501  LEU A O   1 
ATOM   3835 C  CB  . LEU A 1 509 ? 16.409  -2.026  36.931  1 9.502  ? 501  LEU A CB  1 
ATOM   3836 C  CG  . LEU A 1 509 ? 16.239  -3.198  37.917  1 10.202 ? 501  LEU A CG  1 
ATOM   3837 C  CD1 . LEU A 1 509 ? 14.722  -3.442  38.052  1 11.799 ? 501  LEU A CD1 1 
ATOM   3838 C  CD2 . LEU A 1 509 ? 16.991  -4.531  37.688  1 12.811 ? 501  LEU A CD2 1 
ATOM   3839 N  N   . PRO A 1 510 ? 18.153  -1.055  34.421  1 10.897 ? 502  PRO A N   1 
ATOM   3840 C  CA  . PRO A 1 510 ? 18.144  -0.205  33.239  1 13.429 ? 502  PRO A CA  1 
ATOM   3841 C  C   . PRO A 1 510 ? 16.749  0.116   32.715  1 16.905 ? 502  PRO A C   1 
ATOM   3842 O  O   . PRO A 1 510 ? 16.597  0.555   31.579  1 19.702 ? 502  PRO A O   1 
ATOM   3843 C  CB  . PRO A 1 510 ? 18.93   -1.026  32.235  1 14.634 ? 502  PRO A CB  1 
ATOM   3844 C  CG  . PRO A 1 510 ? 18.652  -2.478  32.604  1 14.482 ? 502  PRO A CG  1 
ATOM   3845 C  CD  . PRO A 1 510 ? 18.444  -2.463  34.144  1 11.286 ? 502  PRO A CD  1 
ATOM   3846 N  N   . PHE A 1 511 ? 15.724  -0.245  33.491  1 13.488 ? 503  PHE A N   1 
ATOM   3847 C  CA  . PHE A 1 511 ? 14.326  -0.106  33.088  1 14.957 ? 503  PHE A CA  1 
ATOM   3848 C  C   . PHE A 1 511 ? 13.475  -0.035  34.337  1 14.754 ? 503  PHE A C   1 
ATOM   3849 O  O   . PHE A 1 511 ? 14.029  -0.253  35.428  1 15.141 ? 503  PHE A O   1 
ATOM   3850 C  CB  . PHE A 1 511 ? 13.902  -1.253  32.126  1 15.571 ? 503  PHE A CB  1 
ATOM   3851 C  CG  . PHE A 1 511 ? 14.225  -2.692  32.538  1 16.686 ? 503  PHE A CG  1 
ATOM   3852 C  CD1 . PHE A 1 511 ? 14.023  -3.18   33.83   1 14.98  ? 503  PHE A CD1 1 
ATOM   3853 C  CD2 . PHE A 1 511 ? 14.685  -3.604  31.583  1 16.57  ? 503  PHE A CD2 1 
ATOM   3854 C  CE1 . PHE A 1 511 ? 14.379  -4.471  34.19   1 16.203 ? 503  PHE A CE1 1 
ATOM   3855 C  CE2 . PHE A 1 511 ? 14.963  -4.947  31.914  1 14.09  ? 503  PHE A CE2 1 
ATOM   3856 C  CZ  . PHE A 1 511 ? 14.851  -5.369  33.234  1 16.455 ? 503  PHE A CZ  1 
ATOM   3857 N  N   . ALA A 1 512 ? 12.17   0.314   34.137  1 16.406 ? 504  ALA A N   1 
ATOM   3858 C  CA  . ALA A 1 512 ? 11.148  0.258   35.18   1 12.413 ? 504  ALA A CA  1 
ATOM   3859 C  C   . ALA A 1 512 ? 10.425  -1.087  35.128  1 13.55  ? 504  ALA A C   1 
ATOM   3860 O  O   . ALA A 1 512 ? 10.251  -1.647  34.041  1 13.041 ? 504  ALA A O   1 
ATOM   3861 C  CB  . ALA A 1 512 ? 10.176  1.396   34.955  1 14.942 ? 504  ALA A CB  1 
ATOM   3862 N  N   . ILE A 1 513 ? 10.078  -1.596  36.311  1 11.935 ? 505  ILE A N   1 
ATOM   3863 C  CA  . ILE A 1 513 ? 9.206   -2.727  36.527  1 14.091 ? 505  ILE A CA  1 
ATOM   3864 C  C   . ILE A 1 513 ? 7.867   -2.201  37.06   1 13.401 ? 505  ILE A C   1 
ATOM   3865 O  O   . ILE A 1 513 ? 7.764   -1.068  37.583  1 11.805 ? 505  ILE A O   1 
ATOM   3866 C  CB  . ILE A 1 513 ? 9.888   -3.813  37.39   1 16.869 ? 505  ILE A CB  1 
ATOM   3867 C  CG1 . ILE A 1 513 ? 10.11   -3.362  38.877  1 18.984 ? 505  ILE A CG1 1 
ATOM   3868 C  CG2 . ILE A 1 513 ? 11.182  -4.295  36.746  1 21.276 ? 505  ILE A CG2 1 
ATOM   3869 C  CD1 . ILE A 1 513 ? 10.926  -4.309  39.773  1 18.059 ? 505  ILE A CD1 1 
ATOM   3870 N  N   . ARG A 1 514 ? 6.812   -3.044  36.989  1 12.276 ? 506  ARG A N   1 
ATOM   3871 C  CA  . ARG A 1 514 ? 5.502   -2.667  37.479  1 14.099 ? 506  ARG A CA  1 
ATOM   3872 C  C   . ARG A 1 514 ? 5.585   -2.335  38.967  1 14.03  ? 506  ARG A C   1 
ATOM   3873 O  O   . ARG A 1 514 ? 6.48    -2.825  39.65   1 11.927 ? 506  ARG A O   1 
ATOM   3874 C  CB  . ARG A 1 514 ? 4.592   -3.912  37.457  1 14.733 ? 506  ARG A CB  1 
ATOM   3875 C  CG  . ARG A 1 514 ? 3.839   -3.98   36.139  1 15.513 ? 506  ARG A CG  1 
ATOM   3876 C  CD  . ARG A 1 514 ? 2.776   -2.881  35.992  1 15.679 ? 506  ARG A CD  1 
ATOM   3877 N  NE  . ARG A 1 514 ? 1.928   -3.225  34.84   1 19.112 ? 506  ARG A NE  1 
ATOM   3878 C  CZ  . ARG A 1 514 ? 0.869   -2.575  34.435  1 17.715 ? 506  ARG A CZ  1 
ATOM   3879 N  NH1 . ARG A 1 514 ? 0.475   -1.494  35.091  1 16.825 ? 506  ARG A NH1 1 
ATOM   3880 N  NH2 . ARG A 1 514 ? 0.225   -2.994  33.352  1 20.482 ? 506  ARG A NH2 1 
ATOM   3881 N  N   . SER A 1 515 ? 4.764   -1.397  39.416  1 11.719 ? 507  SER A N   1 
ATOM   3882 C  CA  . SER A 1 515 ? 4.677   -1.224  40.866  1 14.127 ? 507  SER A CA  1 
ATOM   3883 C  C   . SER A 1 515 ? 3.897   -2.43   41.362  1 16.43  ? 507  SER A C   1 
ATOM   3884 O  O   . SER A 1 515 ? 2.923   -2.826  40.716  1 14.408 ? 507  SER A O   1 
ATOM   3885 C  CB  . SER A 1 515 ? 3.976   0.071   41.242  1 13.881 ? 507  SER A CB  1 
ATOM   3886 O  OG  . SER A 1 515 ? 3.952   0.29    42.674  1 14.758 ? 507  SER A OG  1 
ATOM   3887 N  N   . GLY A 1 516 ? 4.396   -3.017  42.451  1 17.623 ? 508  GLY A N   1 
ATOM   3888 C  CA  . GLY A 1 516 ? 3.918   -4.316  42.873  1 14.335 ? 508  GLY A CA  1 
ATOM   3889 C  C   . GLY A 1 516 ? 3.11    -4.268  44.152  1 12.797 ? 508  GLY A C   1 
ATOM   3890 O  O   . GLY A 1 516 ? 2.597   -3.22   44.529  1 14.51  ? 508  GLY A O   1 
ATOM   3891 N  N   . ILE A 1 517 ? 2.875   -5.472  44.69   1 11.893 ? 509  ILE A N   1 
ATOM   3892 C  CA  . ILE A 1 517 ? 2.022   -5.644  45.82   1 13.532 ? 509  ILE A CA  1 
ATOM   3893 C  C   . ILE A 1 517 ? 2.916   -5.88   47.041  1 13.099 ? 509  ILE A C   1 
ATOM   3894 O  O   . ILE A 1 517 ? 3.496   -4.931  47.533  1 12.271 ? 509  ILE A O   1 
ATOM   3895 C  CB  . ILE A 1 517 ? 0.916   -6.699  45.547  1 14.11  ? 509  ILE A CB  1 
ATOM   3896 C  CG1 . ILE A 1 517 ? 0.211   -6.485  44.187  1 12.926 ? 509  ILE A CG1 1 
ATOM   3897 C  CG2 . ILE A 1 517 ? -0.105  -6.689  46.679  1 12.417 ? 509  ILE A CG2 1 
ATOM   3898 C  CD1 . ILE A 1 517 ? -0.642  -5.234  44.129  1 18.108 ? 509  ILE A CD1 1 
ATOM   3899 N  N   . HIS A 1 518 ? 3.163   -7.153  47.409  1 16.352 ? 510  HIS A N   1 
ATOM   3900 C  CA  . HIS A 1 518 ? 4.114   -7.5    48.473  1 16.573 ? 510  HIS A CA  1 
ATOM   3901 C  C   . HIS A 1 518 ? 5.421   -8.067  47.915  1 16.096 ? 510  HIS A C   1 
ATOM   3902 O  O   . HIS A 1 518 ? 5.565   -8.376  46.715  1 14.034 ? 510  HIS A O   1 
ATOM   3903 C  CB  . HIS A 1 518 ? 3.493   -8.528  49.432  1 14.802 ? 510  HIS A CB  1 
ATOM   3904 C  CG  . HIS A 1 518 ? 2.244   -8.016  50.069  1 12.46  ? 510  HIS A CG  1 
ATOM   3905 N  ND1 . HIS A 1 518 ? 2.343   -7.215  51.18   1 14.929 ? 510  HIS A ND1 1 
ATOM   3906 C  CD2 . HIS A 1 518 ? 0.915   -8.132  49.777  1 12.867 ? 510  HIS A CD2 1 
ATOM   3907 C  CE1 . HIS A 1 518 ? 1.096   -6.806  51.506  1 15.44  ? 510  HIS A CE1 1 
ATOM   3908 N  NE2 . HIS A 1 518 ? 0.242   -7.381  50.694  1 11.86  ? 510  HIS A NE2 1 
ATOM   3909 N  N   . GLY A 1 519 ? 6.396   -8.116  48.806  1 12.744 ? 511  GLY A N   1 
ATOM   3910 C  CA  . GLY A 1 519 ? 7.688   -8.777  48.567  1 11.241 ? 511  GLY A CA  1 
ATOM   3911 C  C   . GLY A 1 519 ? 8.229   -9.285  49.897  1 13.28  ? 511  GLY A C   1 
ATOM   3912 O  O   . GLY A 1 519 ? 7.692   -8.894  50.939  1 15.019 ? 511  GLY A O   1 
ATOM   3913 N  N   . GLN A 1 520 ? 9.274   -10.158 49.833  1 13.159 ? 512  GLN A N   1 
ATOM   3914 C  CA  . GLN A 1 520 ? 9.74    -10.728 51.076  1 14.1   ? 512  GLN A CA  1 
ATOM   3915 C  C   . GLN A 1 520 ? 11.257  -10.779 50.957  1 16.542 ? 512  GLN A C   1 
ATOM   3916 O  O   . GLN A 1 520 ? 11.773  -10.971 49.848  1 14.459 ? 512  GLN A O   1 
ATOM   3917 C  CB  . GLN A 1 520 ? 9.131   -12.138 51.183  1 14.035 ? 512  GLN A CB  1 
ATOM   3918 C  CG  . GLN A 1 520 ? 7.601   -12.153 51.334  1 13.988 ? 512  GLN A CG  1 
ATOM   3919 C  CD  . GLN A 1 520 ? 7.008   -11.468 52.564  1 17.979 ? 512  GLN A CD  1 
ATOM   3920 O  OE1 . GLN A 1 520 ? 7.646   -11.383 53.624  1 16.717 ? 512  GLN A OE1 1 
ATOM   3921 N  NE2 . GLN A 1 520 ? 5.764   -10.981 52.461  1 15.743 ? 512  GLN A NE2 1 
ATOM   3922 N  N   . TRP A 1 521 ? 11.933  -10.525 52.097  1 13.081 ? 513  TRP A N   1 
ATOM   3923 C  CA  . TRP A 1 521 ? 13.29   -10.974 52.238  1 16.965 ? 513  TRP A CA  1 
ATOM   3924 C  C   . TRP A 1 521 ? 13.275  -12.468 52.603  1 15.673 ? 513  TRP A C   1 
ATOM   3925 O  O   . TRP A 1 521 ? 12.81   -12.845 53.694  1 14.165 ? 513  TRP A O   1 
ATOM   3926 C  CB  . TRP A 1 521 ? 14.051  -10.135 53.274  1 14.906 ? 513  TRP A CB  1 
ATOM   3927 C  CG  . TRP A 1 521 ? 15.469  -10.635 53.37   1 19.126 ? 513  TRP A CG  1 
ATOM   3928 C  CD1 . TRP A 1 521 ? 16.02   -11.389 54.379  1 23.422 ? 513  TRP A CD1 1 
ATOM   3929 C  CD2 . TRP A 1 521 ? 16.501  -10.455 52.371  1 22.657 ? 513  TRP A CD2 1 
ATOM   3930 N  NE1 . TRP A 1 521 ? 17.352  -11.665 54.101  1 23.355 ? 513  TRP A NE1 1 
ATOM   3931 C  CE2 . TRP A 1 521 ? 17.661  -11.106 52.869  1 23.687 ? 513  TRP A CE2 1 
ATOM   3932 C  CE3 . TRP A 1 521 ? 16.555  -9.81   51.114  1 22.147 ? 513  TRP A CE3 1 
ATOM   3933 C  CZ2 . TRP A 1 521 ? 18.86   -11.091 52.157  1 20.32  ? 513  TRP A CZ2 1 
ATOM   3934 C  CZ3 . TRP A 1 521 ? 17.741  -9.831  50.395  1 20.275 ? 513  TRP A CZ3 1 
ATOM   3935 C  CH2 . TRP A 1 521 ? 18.886  -10.459 50.926  1 18.698 ? 513  TRP A CH2 1 
ATOM   3936 N  N   . ILE A 1 522 ? 13.831  -13.279 51.685  1 15.986 ? 514  ILE A N   1 
ATOM   3937 C  CA  . ILE A 1 522 ? 13.996  -14.71  51.922  1 17.394 ? 514  ILE A CA  1 
ATOM   3938 C  C   . ILE A 1 522 ? 15.467  -15.072 52.177  1 24.256 ? 514  ILE A C   1 
ATOM   3939 O  O   . ILE A 1 522 ? 16.289  -15.137 51.232  1 20.425 ? 514  ILE A O   1 
ATOM   3940 C  CB  . ILE A 1 522 ? 13.335  -15.546 50.823  1 16.155 ? 514  ILE A CB  1 
ATOM   3941 C  CG1 . ILE A 1 522 ? 11.84   -15.177 50.588  1 16.833 ? 514  ILE A CG1 1 
ATOM   3942 C  CG2 . ILE A 1 522 ? 13.56   -17.052 51.093  1 13.491 ? 514  ILE A CG2 1 
ATOM   3943 C  CD1 . ILE A 1 522 ? 10.947  -15.265 51.839  1 17.757 ? 514  ILE A CD1 1 
ATOM   3944 N  N   . PRO A 1 523 ? 15.834  -15.4   53.442  1 18.801 ? 515  PRO A N   1 
ATOM   3945 C  CA  . PRO A 1 523 ? 17.192  -15.785 53.786  1 20.316 ? 515  PRO A CA  1 
ATOM   3946 C  C   . PRO A 1 523 ? 17.756  -16.886 52.914  1 16.441 ? 515  PRO A C   1 
ATOM   3947 O  O   . PRO A 1 523 ? 17.063  -17.853 52.603  1 20.991 ? 515  PRO A O   1 
ATOM   3948 C  CB  . PRO A 1 523 ? 17.042  -16.408 55.23   1 21.439 ? 515  PRO A CB  1 
ATOM   3949 C  CG  . PRO A 1 523 ? 15.906  -15.576 55.792  1 21.078 ? 515  PRO A CG  1 
ATOM   3950 C  CD  . PRO A 1 523 ? 14.945  -15.432 54.626  1 17.529 ? 515  PRO A CD  1 
ATOM   3951 N  N   . GLY A 1 524 ? 19.058  -16.769 52.56   1 18.582 ? 516  GLY A N   1 
ATOM   3952 C  CA  . GLY A 1 524 ? 19.707  -17.857 51.813  1 19.63  ? 516  GLY A CA  1 
ATOM   3953 C  C   . GLY A 1 524 ? 19.529  -19.25  52.442  1 21.089 ? 516  GLY A C   1 
ATOM   3954 O  O   . GLY A 1 524 ? 19.407  -20.264 51.747  1 18.982 ? 516  GLY A O   1 
ATOM   3955 N  N   . GLU A 1 525 ? 19.525  -19.266 53.78   1 23.137 ? 517  GLU A N   1 
ATOM   3956 C  CA  . GLU A 1 525 ? 19.613  -20.455 54.621  1 20.72  ? 517  GLU A CA  1 
ATOM   3957 C  C   . GLU A 1 525 ? 18.339  -21.292 54.564  1 20.397 ? 517  GLU A C   1 
ATOM   3958 O  O   . GLU A 1 525 ? 18.427  -22.492 54.793  1 18.047 ? 517  GLU A O   1 
ATOM   3959 C  CB  . GLU A 1 525 ? 19.993  -20.041 56.053  1 23.024 ? 517  GLU A CB  1 
ATOM   3960 C  CG  . GLU A 1 525 ? 21.416  -19.495 56.146  1 34.857 ? 517  GLU A CG  1 
ATOM   3961 C  CD  . GLU A 1 525 ? 21.655  -18.008 55.855  1 45.389 ? 517  GLU A CD  1 
ATOM   3962 O  OE1 . GLU A 1 525 ? 20.784  -17.242 55.306  1 35.111 ? 517  GLU A OE1 1 
ATOM   3963 O  OE2 . GLU A 1 525 ? 22.789  -17.593 56.232  1 47.673 ? 517  GLU A OE2 1 
ATOM   3964 N  N   . VAL A 1 526 ? 17.197  -20.672 54.193  1 17.938 ? 518  VAL A N   1 
ATOM   3965 C  CA  . VAL A 1 526 ? 15.925  -21.344 54.09   1 17.729 ? 518  VAL A CA  1 
ATOM   3966 C  C   . VAL A 1 526 ? 15.618  -21.582 52.608  1 16.812 ? 518  VAL A C   1 
ATOM   3967 O  O   . VAL A 1 526 ? 14.548  -22.104 52.306  1 18.83  ? 518  VAL A O   1 
ATOM   3968 C  CB  . VAL A 1 526 ? 14.823  -20.504 54.783  1 21.929 ? 518  VAL A CB  1 
ATOM   3969 C  CG1 . VAL A 1 526 ? 15.121  -20.196 56.265  1 19.965 ? 518  VAL A CG1 1 
ATOM   3970 C  CG2 . VAL A 1 526 ? 14.5    -19.197 54.058  1 22.301 ? 518  VAL A CG2 1 
ATOM   3971 N  N   . THR A 1 527 ? 16.562  -21.226 51.72   1 16.689 ? 519  THR A N   1 
ATOM   3972 C  CA  . THR A 1 527 ? 16.346  -21.449 50.289  1 16.584 ? 519  THR A CA  1 
ATOM   3973 C  C   . THR A 1 527 ? 17.092  -22.718 49.873  1 16.184 ? 519  THR A C   1 
ATOM   3974 O  O   . THR A 1 527 ? 18.307  -22.712 49.908  1 16.651 ? 519  THR A O   1 
ATOM   3975 C  CB  . THR A 1 527 ? 16.797  -20.216 49.494  1 17.236 ? 519  THR A CB  1 
ATOM   3976 O  OG1 . THR A 1 527 ? 16.184  -19.055 50.032  1 19.465 ? 519  THR A OG1 1 
ATOM   3977 C  CG2 . THR A 1 527 ? 16.45   -20.276 48.007  1 14.531 ? 519  THR A CG2 1 
ATOM   3978 N  N   . PRO A 1 528 ? 16.441  -23.78  49.363  1 16.968 ? 520  PRO A N   1 
ATOM   3979 C  CA  . PRO A 1 528 ? 17.177  -24.931 48.856  1 21.021 ? 520  PRO A CA  1 
ATOM   3980 C  C   . PRO A 1 528 ? 18.197  -24.495 47.798  1 23.109 ? 520  PRO A C   1 
ATOM   3981 O  O   . PRO A 1 528 ? 17.898  -23.613 46.963  1 23.594 ? 520  PRO A O   1 
ATOM   3982 C  CB  . PRO A 1 528 ? 16.135  -25.882 48.338  1 19.807 ? 520  PRO A CB  1 
ATOM   3983 C  CG  . PRO A 1 528 ? 14.812  -25.41  48.988  1 19.294 ? 520  PRO A CG  1 
ATOM   3984 C  CD  . PRO A 1 528 ? 14.968  -23.958 49.267  1 16.762 ? 520  PRO A CD  1 
ATOM   3985 N  N   . ASP A 1 529 ? 19.442  -25.013 47.963  1 17.702 ? 521  ASP A N   1 
ATOM   3986 C  CA  . ASP A 1 529 ? 20.492  -24.959 46.952  1 21.973 ? 521  ASP A CA  1 
ATOM   3987 C  C   . ASP A 1 529 ? 20.927  -23.519 46.671  1 21.738 ? 521  ASP A C   1 
ATOM   3988 O  O   . ASP A 1 529 ? 21.337  -23.252 45.539  1 25.007 ? 521  ASP A O   1 
ATOM   3989 C  CB  . ASP A 1 529 ? 20.016  -25.59  45.647  1 18.645 ? 521  ASP A CB  1 
ATOM   3990 C  CG  . ASP A 1 529 ? 19.502  -26.999 45.783  1 20.791 ? 521  ASP A CG  1 
ATOM   3991 O  OD1 . ASP A 1 529 ? 20.26   -27.858 46.266  1 24.215 ? 521  ASP A OD1 1 
ATOM   3992 O  OD2 . ASP A 1 529 ? 18.35   -27.226 45.458  1 22.311 ? 521  ASP A OD2 1 
ATOM   3993 N  N   . PHE A 1 530 ? 20.759  -22.616 47.661  1 18.533 ? 522  PHE A N   1 
ATOM   3994 C  CA  . PHE A 1 530 ? 21.121  -21.217 47.515  1 19.481 ? 522  PHE A CA  1 
ATOM   3995 C  C   . PHE A 1 530 ? 22.64   -21.09  47.345  1 23.857 ? 522  PHE A C   1 
ATOM   3996 O  O   . PHE A 1 530 ? 23.12   -20.163 46.694  1 20.226 ? 522  PHE A O   1 
ATOM   3997 C  CB  . PHE A 1 530 ? 20.637  -20.409 48.72   1 20.631 ? 522  PHE A CB  1 
ATOM   3998 C  CG  . PHE A 1 530 ? 20.962  -18.917 48.708  1 20.092 ? 522  PHE A CG  1 
ATOM   3999 C  CD1 . PHE A 1 530 ? 22.194  -18.447 49.211  1 20.493 ? 522  PHE A CD1 1 
ATOM   4000 C  CD2 . PHE A 1 530 ? 20.087  -18.006 48.083  1 16.881 ? 522  PHE A CD2 1 
ATOM   4001 C  CE1 . PHE A 1 530 ? 22.524  -17.101 49.148  1 22.094 ? 522  PHE A CE1 1 
ATOM   4002 C  CE2 . PHE A 1 530 ? 20.381  -16.626 48.101  1 18.297 ? 522  PHE A CE2 1 
ATOM   4003 C  CZ  . PHE A 1 530 ? 21.611  -16.181 48.589  1 18.132 ? 522  PHE A CZ  1 
ATOM   4004 N  N   . GLU A 1 531 ? 23.397  -22.011 47.949  1 26.109 ? 523  GLU A N   1 
ATOM   4005 C  CA  . GLU A 1 531 ? 24.852  -22.061 47.856  1 24.741 ? 523  GLU A CA  1 
ATOM   4006 C  C   . GLU A 1 531 ? 25.372  -22.544 46.502  1 21.505 ? 523  GLU A C   1 
ATOM   4007 O  O   . GLU A 1 531 ? 26.541  -22.244 46.191  1 27.917 ? 523  GLU A O   1 
ATOM   4008 C  CB  . GLU A 1 531 ? 25.476  -22.833 49.021  1 21.801 ? 523  GLU A CB  1 
ATOM   4009 C  CG  . GLU A 1 531 ? 25.249  -22.179 50.384  1 23.708 ? 523  GLU A CG  1 
ATOM   4010 C  CD  . GLU A 1 531 ? 25.628  -20.71  50.536  1 31.462 ? 523  GLU A CD  1 
ATOM   4011 O  OE1 . GLU A 1 531 ? 26.664  -20.225 50.003  1 35.693 ? 523  GLU A OE1 1 
ATOM   4012 O  OE2 . GLU A 1 531 ? 24.902  -20.049 51.305  1 29.346 ? 523  GLU A OE2 1 
ATOM   4013 N  N   . THR A 1 532 ? 24.552  -23.196 45.669  1 20.99  ? 524  THR A N   1 
ATOM   4014 C  CA  . THR A 1 532 ? 24.992  -23.779 44.404  1 21.643 ? 524  THR A CA  1 
ATOM   4015 C  C   . THR A 1 532 ? 24.294  -23.249 43.137  1 24.124 ? 524  THR A C   1 
ATOM   4016 O  O   . THR A 1 532 ? 24.741  -23.523 42.021  1 23.365 ? 524  THR A O   1 
ATOM   4017 C  CB  . THR A 1 532 ? 25.008  -25.301 44.441  1 22.036 ? 524  THR A CB  1 
ATOM   4018 O  OG1 . THR A 1 532 ? 23.682  -25.789 44.518  1 20.667 ? 524  THR A OG1 1 
ATOM   4019 C  CG2 . THR A 1 532 ? 25.908  -25.894 45.52   1 27.389 ? 524  THR A CG2 1 
ATOM   4020 N  N   . LYS A 1 533 ? 23.179  -22.523 43.303  1 25.049 ? 525  LYS A N   1 
ATOM   4021 C  CA  . LYS A 1 533 ? 22.339  -22.087 42.19   1 23.043 ? 525  LYS A CA  1 
ATOM   4022 C  C   . LYS A 1 533 ? 22.201  -20.581 42.321  1 26.976 ? 525  LYS A C   1 
ATOM   4023 O  O   . LYS A 1 533 ? 21.886  -20.086 43.407  1 30.11  ? 525  LYS A O   1 
ATOM   4024 C  CB  . LYS A 1 533 ? 20.988  -22.807 42.198  1 21.198 ? 525  LYS A CB  1 
ATOM   4025 C  CG  . LYS A 1 533 ? 21.078  -24.204 41.653  1 23.825 ? 525  LYS A CG  1 
ATOM   4026 C  CD  . LYS A 1 533 ? 19.815  -24.978 41.969  1 32.12  ? 525  LYS A CD  1 
ATOM   4027 C  CE  . LYS A 1 533 ? 20.062  -26.454 41.922  1 41.288 ? 525  LYS A CE  1 
ATOM   4028 N  NZ  . LYS A 1 533 ? 18.841  -27.148 42.337  1 50.706 ? 525  LYS A NZ  1 
ATOM   4029 N  N   . GLY A 1 534 ? 22.511  -19.854 41.23   1 25.259 ? 526  GLY A N   1 
ATOM   4030 C  CA  . GLY A 1 534 ? 22.221  -18.424 41.207  1 22.552 ? 526  GLY A CA  1 
ATOM   4031 C  C   . GLY A 1 534 ? 20.918  -18.222 40.438  1 20.957 ? 526  GLY A C   1 
ATOM   4032 O  O   . GLY A 1 534 ? 20.348  -19.198 39.976  1 20.612 ? 526  GLY A O   1 
ATOM   4033 N  N   . LEU A 1 535 ? 20.465  -16.969 40.331  1 16.2   ? 527  LEU A N   1 
ATOM   4034 C  CA  . LEU A 1 535 ? 19.291  -16.646 39.505  1 17.817 ? 527  LEU A CA  1 
ATOM   4035 C  C   . LEU A 1 535 ? 19.625  -16.826 38.023  1 16.003 ? 527  LEU A C   1 
ATOM   4036 O  O   . LEU A 1 535 ? 18.725  -17.096 37.206  1 19.224 ? 527  LEU A O   1 
ATOM   4037 C  CB  . LEU A 1 535 ? 18.904  -15.19  39.785  1 16.446 ? 527  LEU A CB  1 
ATOM   4038 C  CG  . LEU A 1 535 ? 18.429  -14.89  41.223  1 15.909 ? 527  LEU A CG  1 
ATOM   4039 C  CD1 . LEU A 1 535 ? 17.94   -13.448 41.265  1 16.022 ? 527  LEU A CD1 1 
ATOM   4040 C  CD2 . LEU A 1 535 ? 17.29   -15.847 41.675  1 17.661 ? 527  LEU A CD2 1 
ATOM   4041 N  N   . VAL A 1 536 ? 20.929  -16.795 37.696  1 16.965 ? 528  VAL A N   1 
ATOM   4042 C  CA  . VAL A 1 536 ? 21.332  -16.924 36.29   1 17.029 ? 528  VAL A CA  1 
ATOM   4043 C  C   . VAL A 1 536 ? 22.241  -18.14  36.19   1 18.116 ? 528  VAL A C   1 
ATOM   4044 O  O   . VAL A 1 536 ? 23.251  -18.158 36.883  1 20.011 ? 528  VAL A O   1 
ATOM   4045 C  CB  . VAL A 1 536 ? 22.09   -15.652 35.854  1 20.333 ? 528  VAL A CB  1 
ATOM   4046 C  CG1 . VAL A 1 536 ? 22.315  -15.629 34.315  1 21.37  ? 528  VAL A CG1 1 
ATOM   4047 C  CG2 . VAL A 1 536 ? 21.407  -14.334 36.267  1 19.911 ? 528  VAL A CG2 1 
ATOM   4048 N  N   . ASP A 1 537 ? 22.029  -19.068 35.246  1 21.349 ? 529  ASP A N   1 
ATOM   4049 C  CA  . ASP A 1 537 ? 22.932  -20.207 35.2    1 23.491 ? 529  ASP A CA  1 
ATOM   4050 C  C   . ASP A 1 537 ? 24.269  -19.784 34.554  1 25.475 ? 529  ASP A C   1 
ATOM   4051 O  O   . ASP A 1 537 ? 24.245  -19.068 33.573  1 21.285 ? 529  ASP A O   1 
ATOM   4052 C  CB  . ASP A 1 537 ? 22.284  -21.395 34.528  1 29.878 ? 529  ASP A CB  1 
ATOM   4053 C  CG  . ASP A 1 537 ? 21.496  -22.367 35.41   1 30.374 ? 529  ASP A CG  1 
ATOM   4054 O  OD1 . ASP A 1 537 ? 21.412  -22.204 36.676  1 33.497 ? 529  ASP A OD1 1 
ATOM   4055 O  OD2 . ASP A 1 537 ? 21.06   -23.367 34.847  1 35.735 ? 529  ASP A OD2 1 
ATOM   4056 N  N   . LEU A 1 538 ? 25.411  -20.171 35.122  1 20.278 ? 530  LEU A N   1 
ATOM   4057 C  CA  . LEU A 1 538 ? 26.698  -19.735 34.596  1 27.08  ? 530  LEU A CA  1 
ATOM   4058 C  C   . LEU A 1 538 ? 26.955  -20.424 33.261  1 22.826 ? 530  LEU A C   1 
ATOM   4059 O  O   . LEU A 1 538 ? 26.545  -21.567 33.071  1 20.198 ? 530  LEU A O   1 
ATOM   4060 C  CB  . LEU A 1 538 ? 27.874  -19.918 35.55   1 30.119 ? 530  LEU A CB  1 
ATOM   4061 C  CG  . LEU A 1 538 ? 27.884  -18.985 36.761  1 33.714 ? 530  LEU A CG  1 
ATOM   4062 C  CD1 . LEU A 1 538 ? 29.122  -19.301 37.576  1 30.691 ? 530  LEU A CD1 1 
ATOM   4063 C  CD2 . LEU A 1 538 ? 27.799  -17.477 36.391  1 32.998 ? 530  LEU A CD2 1 
ATOM   4064 N  N   . PRO A 1 539 ? 27.623  -19.778 32.276  1 21.569 ? 531  PRO A N   1 
ATOM   4065 C  CA  . PRO A 1 539 ? 28.039  -20.536 31.104  1 20.795 ? 531  PRO A CA  1 
ATOM   4066 C  C   . PRO A 1 539 ? 29.13   -21.552 31.454  1 17.178 ? 531  PRO A C   1 
ATOM   4067 O  O   . PRO A 1 539 ? 29.781  -21.446 32.532  1 15.749 ? 531  PRO A O   1 
ATOM   4068 C  CB  . PRO A 1 539 ? 28.262  -19.463 30.023  1 20.999 ? 531  PRO A CB  1 
ATOM   4069 C  CG  . PRO A 1 539 ? 28.755  -18.308 30.894  1 25.082 ? 531  PRO A CG  1 
ATOM   4070 C  CD  . PRO A 1 539 ? 27.958  -18.34  32.182  1 23.046 ? 531  PRO A CD  1 
ATOM   4071 N  N   . LYS A 1 540 ? 29.376  -22.471 30.511  1 17.632 ? 532  LYS A N   1 
ATOM   4072 C  CA  . LYS A 1 540 ? 30.334  -23.563 30.711  1 18.17  ? 532  LYS A CA  1 
ATOM   4073 C  C   . LYS A 1 540 ? 31.754  -23.005 30.862  1 19.414 ? 532  LYS A C   1 
ATOM   4074 O  O   . LYS A 1 540 ? 32.058  -21.923 30.369  1 17.62  ? 532  LYS A O   1 
ATOM   4075 C  CB  . LYS A 1 540 ? 30.278  -24.599 29.588  1 18.663 ? 532  LYS A CB  1 
ATOM   4076 C  CG  . LYS A 1 540 ? 30.607  -24.123 28.178  1 20.687 ? 532  LYS A CG  1 
ATOM   4077 C  CD  . LYS A 1 540 ? 30.703  -25.401 27.327  1 25.057 ? 532  LYS A CD  1 
ATOM   4078 C  CE  . LYS A 1 540 ? 31.114  -25.121 25.934  1 26.313 ? 532  LYS A CE  1 
ATOM   4079 N  NZ  . LYS A 1 540 ? 31.204  -26.344 25.116  1 24.2   ? 532  LYS A NZ  1 
ATOM   4080 N  N   . GLU A 1 541 ? 32.605  -23.737 31.563  1 20.345 ? 533  GLU A N   1 
ATOM   4081 C  CA  . GLU A 1 541 ? 34.006  -23.398 31.736  1 19.129 ? 533  GLU A CA  1 
ATOM   4082 C  C   . GLU A 1 541 ? 34.821  -23.583 30.451  1 18.449 ? 533  GLU A C   1 
ATOM   4083 O  O   . GLU A 1 541 ? 35.604  -22.688 30.068  1 20.193 ? 533  GLU A O   1 
ATOM   4084 C  CB  . GLU A 1 541 ? 34.621  -24.085 32.954  1 23.075 ? 533  GLU A CB  1 
ATOM   4085 C  CG  . GLU A 1 541 ? 35.975  -23.478 33.26   1 24.774 ? 533  GLU A CG  1 
ATOM   4086 C  CD  . GLU A 1 541 ? 36.609  -24.164 34.459  1 38.296 ? 533  GLU A CD  1 
ATOM   4087 O  OE1 . GLU A 1 541 ? 36.169  -25.283 34.815  1 41.345 ? 533  GLU A OE1 1 
ATOM   4088 O  OE2 . GLU A 1 541 ? 37.528  -23.551 35.042  1 40.962 ? 533  GLU A OE2 1 
ATOM   4089 N  N   . GLU A 1 542 ? 34.684  -24.733 29.821  1 22.257 ? 534  GLU A N   1 
ATOM   4090 C  CA  . GLU A 1 542 ? 35.429  -25.072 28.607  1 22.745 ? 534  GLU A CA  1 
ATOM   4091 C  C   . GLU A 1 542 ? 35.265  -23.98  27.542  1 17.003 ? 534  GLU A C   1 
ATOM   4092 O  O   . GLU A 1 542 ? 34.202  -23.471 27.382  1 19.57  ? 534  GLU A O   1 
ATOM   4093 C  CB  . GLU A 1 542 ? 34.906  -26.328 27.909  1 23.152 ? 534  GLU A CB  1 
ATOM   4094 C  CG  . GLU A 1 542 ? 35.936  -26.942 26.953  1 28.203 ? 534  GLU A CG  1 
ATOM   4095 C  CD  . GLU A 1 542 ? 36      -28.453 26.847  1 43.961 ? 534  GLU A CD  1 
ATOM   4096 O  OE1 . GLU A 1 542 ? 34.969  -29.086 26.53   1 41.083 ? 534  GLU A OE1 1 
ATOM   4097 O  OE2 . GLU A 1 542 ? 37.103  -28.993 27.11   1 54.321 ? 534  GLU A OE2 1 
ATOM   4098 N  N   . HIS A 1 543 ? 36.355  -23.563 26.901  1 17.435 ? 535  HIS A N   1 
ATOM   4099 C  CA  . HIS A 1 543 ? 36.356  -22.65  25.781  1 18.827 ? 535  HIS A CA  1 
ATOM   4100 C  C   . HIS A 1 543 ? 35.691  -23.345 24.596  1 18.206 ? 535  HIS A C   1 
ATOM   4101 O  O   . HIS A 1 543 ? 35.894  -24.536 24.348  1 17.381 ? 535  HIS A O   1 
ATOM   4102 C  CB  . HIS A 1 543 ? 37.809  -22.251 25.456  1 20.644 ? 535  HIS A CB  1 
ATOM   4103 C  CG  . HIS A 1 543 ? 38.435  -21.386 26.502  1 24.038 ? 535  HIS A CG  1 
ATOM   4104 N  ND1 . HIS A 1 543 ? 39.776  -21.432 26.838  1 27.598 ? 535  HIS A ND1 1 
ATOM   4105 C  CD2 . HIS A 1 543 ? 37.886  -20.45  27.309  1 25.873 ? 535  HIS A CD2 1 
ATOM   4106 C  CE1 . HIS A 1 543 ? 40.018  -20.529 27.798  1 22.107 ? 535  HIS A CE1 1 
ATOM   4107 N  NE2 . HIS A 1 543 ? 38.881  -19.929 28.104  1 28.039 ? 535  HIS A NE2 1 
ATOM   4108 N  N   . TRP A 1 544 ? 34.929  -22.583 23.837  1 17.649 ? 536  TRP A N   1 
ATOM   4109 C  CA  . TRP A 1 544 ? 34.453  -23.085 22.551  1 21.123 ? 536  TRP A CA  1 
ATOM   4110 C  C   . TRP A 1 544 ? 35.608  -23.218 21.585  1 18.947 ? 536  TRP A C   1 
ATOM   4111 O  O   . TRP A 1 544 ? 35.652  -24.161 20.808  1 18.244 ? 536  TRP A O   1 
ATOM   4112 C  CB  . TRP A 1 544 ? 33.395  -22.183 21.905  1 20.993 ? 536  TRP A CB  1 
ATOM   4113 C  CG  . TRP A 1 544 ? 32.135  -21.959 22.69   1 20.946 ? 536  TRP A CG  1 
ATOM   4114 C  CD1 . TRP A 1 544 ? 31.771  -20.79  23.309  1 18.748 ? 536  TRP A CD1 1 
ATOM   4115 C  CD2 . TRP A 1 544 ? 31.016  -22.864 22.811  1 18.887 ? 536  TRP A CD2 1 
ATOM   4116 N  NE1 . TRP A 1 544 ? 30.53   -20.962 23.864  1 19.05  ? 536  TRP A NE1 1 
ATOM   4117 C  CE2 . TRP A 1 544 ? 30.042  -22.208 23.585  1 17.972 ? 536  TRP A CE2 1 
ATOM   4118 C  CE3 . TRP A 1 544 ? 30.756  -24.172 22.393  1 19.317 ? 536  TRP A CE3 1 
ATOM   4119 C  CZ2 . TRP A 1 544 ? 28.803  -22.781 23.908  1 20.393 ? 536  TRP A CZ2 1 
ATOM   4120 C  CZ3 . TRP A 1 544 ? 29.538  -24.745 22.705  1 23.821 ? 536  TRP A CZ3 1 
ATOM   4121 C  CH2 . TRP A 1 544 ? 28.559  -24.065 23.463  1 23.9   ? 536  TRP A CH2 1 
ATOM   4122 N  N   . ALA A 1 545 ? 36.54   -22.255 21.627  1 19.774 ? 537  ALA A N   1 
ATOM   4123 C  CA  . ALA A 1 545 ? 37.475  -22.184 20.527  1 17.86  ? 537  ALA A CA  1 
ATOM   4124 C  C   . ALA A 1 545 ? 38.775  -22.943 20.826  1 13.907 ? 537  ALA A C   1 
ATOM   4125 O  O   . ALA A 1 545 ? 39.203  -23.045 22.003  1 16.023 ? 537  ALA A O   1 
ATOM   4126 C  CB  . ALA A 1 545 ? 37.681  -20.71  20.173  1 14.91  ? 537  ALA A CB  1 
ATOM   4127 N  N   . PRO A 1 546 ? 39.453  -23.51  19.805  1 14.35  ? 538  PRO A N   1 
ATOM   4128 C  CA  . PRO A 1 546 ? 40.764  -24.128 20.035  1 17.556 ? 538  PRO A CA  1 
ATOM   4129 C  C   . PRO A 1 546 ? 41.856  -23.105 20.338  1 21.108 ? 538  PRO A C   1 
ATOM   4130 O  O   . PRO A 1 546 ? 41.711  -21.958 19.907  1 18.833 ? 538  PRO A O   1 
ATOM   4131 C  CB  . PRO A 1 546 ? 40.963  -24.955 18.758  1 19.251 ? 538  PRO A CB  1 
ATOM   4132 C  CG  . PRO A 1 546 ? 40.236  -24.134 17.727  1 16.698 ? 538  PRO A CG  1 
ATOM   4133 C  CD  . PRO A 1 546 ? 39.035  -23.562 18.37   1 16.985 ? 538  PRO A CD  1 
ATOM   4134 N  N   . LEU A 1 547 ? 42.953  -23.533 21.039  1 22.041 ? 539  LEU A N   1 
ATOM   4135 C  CA  . LEU A 1 547 ? 44.096  -22.666 21.322  1 22.961 ? 539  LEU A CA  1 
ATOM   4136 C  C   . LEU A 1 547 ? 44.692  -22.06  20.047  1 21.031 ? 539  LEU A C   1 
ATOM   4137 O  O   . LEU A 1 547 ? 45.096  -20.897 20.056  1 26.607 ? 539  LEU A O   1 
ATOM   4138 C  CB  . LEU A 1 547 ? 45.157  -23.419 22.102  1 27.815 ? 539  LEU A CB  1 
ATOM   4139 C  CG  . LEU A 1 547 ? 46.231  -22.523 22.726  1 27.118 ? 539  LEU A CG  1 
ATOM   4140 C  CD1 . LEU A 1 547 ? 45.763  -21.827 23.997  1 30.784 ? 539  LEU A CD1 1 
ATOM   4141 C  CD2 . LEU A 1 547 ? 47.553  -23.268 22.889  1 32.948 ? 539  LEU A CD2 1 
ATOM   4142 N  N   . SER A 1 548 ? 44.647  -22.826 18.971  1 18.878 ? 540  SER A N   1 
ATOM   4143 C  CA  . SER A 1 548 ? 45.255  -22.437 17.698  1 21.505 ? 540  SER A CA  1 
ATOM   4144 C  C   . SER A 1 548 ? 44.605  -21.202 17.073  1 23.225 ? 540  SER A C   1 
ATOM   4145 O  O   . SER A 1 548 ? 45.174  -20.584 16.183  1 23.104 ? 540  SER A O   1 
ATOM   4146 C  CB  . SER A 1 548 ? 45.202  -23.573 16.714  1 21.009 ? 540  SER A CB  1 
ATOM   4147 O  OG  . SER A 1 548 ? 43.861  -23.877 16.375  1 19.854 ? 540  SER A OG  1 
ATOM   4148 N  N   . GLN A 1 549 ? 43.369  -20.89  17.483  1 23.383 ? 541  GLN A N   1 
ATOM   4149 C  CA  . GLN A 1 549 ? 42.613  -19.804 16.891  1 21.939 ? 541  GLN A CA  1 
ATOM   4150 C  C   . GLN A 1 549 ? 42.994  -18.457 17.517  1 20.884 ? 541  GLN A C   1 
ATOM   4151 O  O   . GLN A 1 549 ? 42.68   -17.445 16.932  1 20.312 ? 541  GLN A O   1 
ATOM   4152 C  CB  . GLN A 1 549 ? 41.118  -20.175 16.979  1 20.472 ? 541  GLN A CB  1 
ATOM   4153 C  CG  . GLN A 1 549 ? 40.681  -21.119 15.866  1 19.193 ? 541  GLN A CG  1 
ATOM   4154 C  CD  . GLN A 1 549 ? 40.337  -20.392 14.584  1 16.531 ? 541  GLN A CD  1 
ATOM   4155 O  OE1 . GLN A 1 549 ? 39.62   -19.38  14.563  1 15.709 ? 541  GLN A OE1 1 
ATOM   4156 N  NE2 . GLN A 1 549 ? 40.824  -20.92  13.466  1 16.785 ? 541  GLN A NE2 1 
ATOM   4157 N  N   . SER A 1 550 ? 43.639  -18.426 18.705  1 21.921 ? 542  SER A N   1 
ATOM   4158 C  CA  . SER A 1 550 ? 43.985  -17.162 19.347  1 20.542 ? 542  SER A CA  1 
ATOM   4159 C  C   . SER A 1 550 ? 44.807  -16.289 18.387  1 18.177 ? 542  SER A C   1 
ATOM   4160 O  O   . SER A 1 550 ? 45.661  -16.803 17.645  1 19.044 ? 542  SER A O   1 
ATOM   4161 C  CB  . SER A 1 550 ? 44.775  -17.317 20.622  1 22.438 ? 542  SER A CB  1 
ATOM   4162 O  OG  . SER A 1 550 ? 44.968  -16.035 21.185  1 18.672 ? 542  SER A OG  1 
ATOM   4163 N  N   . PRO A 1 551 ? 44.53   -14.961 18.311  1 15.506 ? 543  PRO A N   1 
ATOM   4164 C  CA  . PRO A 1 551 ? 45.351  -14.075 17.509  1 16.859 ? 543  PRO A CA  1 
ATOM   4165 C  C   . PRO A 1 551 ? 46.746  -13.923 18.113  1 16.553 ? 543  PRO A C   1 
ATOM   4166 O  O   . PRO A 1 551 ? 47.657  -13.599 17.398  1 15.423 ? 543  PRO A O   1 
ATOM   4167 C  CB  . PRO A 1 551 ? 44.615  -12.738 17.544  1 14.564 ? 543  PRO A CB  1 
ATOM   4168 C  CG  . PRO A 1 551 ? 43.857  -12.815 18.898  1 15.648 ? 543  PRO A CG  1 
ATOM   4169 C  CD  . PRO A 1 551 ? 43.387  -14.249 18.89   1 17.769 ? 543  PRO A CD  1 
ATOM   4170 N  N   . TYR A 1 552 ? 46.863  -14.195 19.414  1 17.183 ? 544  TYR A N   1 
ATOM   4171 C  CA  . TYR A 1 552 ? 48.104  -13.994 20.148  1 15.66  ? 544  TYR A CA  1 
ATOM   4172 C  C   . TYR A 1 552 ? 48.959  -15.248 20.023  1 17.002 ? 544  TYR A C   1 
ATOM   4173 O  O   . TYR A 1 552 ? 48.449  -16.385 20.114  1 19.196 ? 544  TYR A O   1 
ATOM   4174 C  CB  . TYR A 1 552 ? 47.656  -13.797 21.605  1 18.199 ? 544  TYR A CB  1 
ATOM   4175 C  CG  . TYR A 1 552 ? 48.83   -13.838 22.581  1 19.767 ? 544  TYR A CG  1 
ATOM   4176 C  CD1 . TYR A 1 552 ? 49.794  -12.798 22.644  1 22.206 ? 544  TYR A CD1 1 
ATOM   4177 C  CD2 . TYR A 1 552 ? 49.042  -14.972 23.349  1 22.943 ? 544  TYR A CD2 1 
ATOM   4178 C  CE1 . TYR A 1 552 ? 50.855  -12.853 23.57   1 18.894 ? 544  TYR A CE1 1 
ATOM   4179 C  CE2 . TYR A 1 552 ? 50.096  -15.029 24.266  1 20.316 ? 544  TYR A CE2 1 
ATOM   4180 C  CZ  . TYR A 1 552 ? 51.005  -13.992 24.345  1 20.699 ? 544  TYR A CZ  1 
ATOM   4181 O  OH  . TYR A 1 552 ? 52.012  -14.137 25.278  1 25.983 ? 544  TYR A OH  1 
ATOM   4182 N  N   . ASP A 1 553 ? 50.254  -15.001 19.781  1 18.386 ? 545  ASP A N   1 
ATOM   4183 C  CA  . ASP A 1 553 ? 51.314  -15.998 19.725  1 19.544 ? 545  ASP A CA  1 
ATOM   4184 C  C   . ASP A 1 553 ? 52.38   -15.591 20.734  1 19.394 ? 545  ASP A C   1 
ATOM   4185 O  O   . ASP A 1 553 ? 53.054  -14.562 20.565  1 23.555 ? 545  ASP A O   1 
ATOM   4186 C  CB  . ASP A 1 553 ? 51.875  -16.133 18.313  1 19.244 ? 545  ASP A CB  1 
ATOM   4187 C  CG  . ASP A 1 553 ? 53.025  -17.127 18.128  1 28.197 ? 545  ASP A CG  1 
ATOM   4188 O  OD1 . ASP A 1 553 ? 53.567  -17.678 19.145  1 20.436 ? 545  ASP A OD1 1 
ATOM   4189 O  OD2 . ASP A 1 553 ? 53.393  -17.341 16.956  1 22.799 ? 545  ASP A OD2 1 
ATOM   4190 N  N   . PRO A 1 554 ? 52.577  -16.345 21.836  1 20.957 ? 546  PRO A N   1 
ATOM   4191 C  CA  . PRO A 1 554 ? 53.588  -15.979 22.819  1 19.31  ? 546  PRO A CA  1 
ATOM   4192 C  C   . PRO A 1 554 ? 55.015  -15.842 22.269  1 20.672 ? 546  PRO A C   1 
ATOM   4193 O  O   . PRO A 1 554 ? 55.806  -15.155 22.886  1 18.58  ? 546  PRO A O   1 
ATOM   4194 C  CB  . PRO A 1 554 ? 53.595  -17.119 23.847  1 21.179 ? 546  PRO A CB  1 
ATOM   4195 C  CG  . PRO A 1 554 ? 52.714  -18.191 23.275  1 20.918 ? 546  PRO A CG  1 
ATOM   4196 C  CD  . PRO A 1 554 ? 51.835  -17.566 22.203  1 23.69  ? 546  PRO A CD  1 
ATOM   4197 N  N   . ASP A 1 555 ? 55.301  -16.416 21.079  1 16.435 ? 547  ASP A N   1 
ATOM   4198 C  CA  . ASP A 1 555 ? 56.62   -16.36  20.467  1 21.381 ? 547  ASP A CA  1 
ATOM   4199 C  C   . ASP A 1 555 ? 56.758  -15.171 19.53   1 24.963 ? 547  ASP A C   1 
ATOM   4200 O  O   . ASP A 1 555 ? 57.896  -14.824 19.156  1 20.957 ? 547  ASP A O   1 
ATOM   4201 C  CB  . ASP A 1 555 ? 57.039  -17.664 19.808  1 21.38  ? 547  ASP A CB  1 
ATOM   4202 C  CG  . ASP A 1 555 ? 57.068  -18.884 20.707  1 23.034 ? 547  ASP A CG  1 
ATOM   4203 O  OD1 . ASP A 1 555 ? 57.55   -18.824 21.839  1 22.541 ? 547  ASP A OD1 1 
ATOM   4204 O  OD2 . ASP A 1 555 ? 56.557  -19.899 20.268  1 33.498 ? 547  ASP A OD2 1 
ATOM   4205 N  N   . ALA A 1 556 ? 55.628  -14.526 19.196  1 19.894 ? 548  ALA A N   1 
ATOM   4206 C  CA  . ALA A 1 556 ? 55.644  -13.396 18.271  1 23.339 ? 548  ALA A CA  1 
ATOM   4207 C  C   . ALA A 1 556 ? 56.336  -12.156 18.842  1 21.58  ? 548  ALA A C   1 
ATOM   4208 O  O   . ALA A 1 556 ? 56.728  -11.324 17.986  1 20.428 ? 548  ALA A O   1 
ATOM   4209 C  CB  . ALA A 1 556 ? 54.231  -13.083 17.751  1 21.784 ? 548  ALA A CB  1 
ATOM   4210 O  OXT . ALA A 1 556 ? 56.438  -11.998 20.092  1 18.358 ? 548  ALA A OXT 1 
ATOM   4211 N  N   . TYR B 1 32  ? 16.788  20.497  41.525  1 37.311 ? 24   TYR B N   1 
ATOM   4212 C  CA  . TYR B 1 32  ? 16.591  19.304  42.411  1 33.52  ? 24   TYR B CA  1 
ATOM   4213 C  C   . TYR B 1 32  ? 17.718  18.304  42.192  1 27.285 ? 24   TYR B C   1 
ATOM   4214 O  O   . TYR B 1 32  ? 18.028  17.967  41.045  1 23.118 ? 24   TYR B O   1 
ATOM   4215 C  CB  . TYR B 1 32  ? 15.22   18.599  42.355  1 33.738 ? 24   TYR B CB  1 
ATOM   4216 C  CG  . TYR B 1 32  ? 15.095  17.346  43.219  1 30.083 ? 24   TYR B CG  1 
ATOM   4217 C  CD1 . TYR B 1 32  ? 14.966  17.46   44.616  1 32.901 ? 24   TYR B CD1 1 
ATOM   4218 C  CD2 . TYR B 1 32  ? 15.232  16.052  42.675  1 25.908 ? 24   TYR B CD2 1 
ATOM   4219 C  CE1 . TYR B 1 32  ? 14.899  16.339  45.43   1 31.733 ? 24   TYR B CE1 1 
ATOM   4220 C  CE2 . TYR B 1 32  ? 15.178  14.923  43.482  1 29.291 ? 24   TYR B CE2 1 
ATOM   4221 C  CZ  . TYR B 1 32  ? 15.01   15.074  44.862  1 34.067 ? 24   TYR B CZ  1 
ATOM   4222 O  OH  . TYR B 1 32  ? 14.924  14.003  45.707  1 35.914 ? 24   TYR B OH  1 
ATOM   4223 N  N   . VAL B 1 33  ? 18.245  17.757  43.297  1 26.444 ? 25   VAL B N   1 
ATOM   4224 C  CA  . VAL B 1 33  ? 19.264  16.694  43.168  1 31.784 ? 25   VAL B CA  1 
ATOM   4225 C  C   . VAL B 1 33  ? 18.863  15.521  44.065  1 30.599 ? 25   VAL B C   1 
ATOM   4226 O  O   . VAL B 1 33  ? 18.622  15.741  45.272  1 29.593 ? 25   VAL B O   1 
ATOM   4227 C  CB  . VAL B 1 33  ? 20.747  17.078  43.423  1 30.37  ? 25   VAL B CB  1 
ATOM   4228 C  CG1 . VAL B 1 33  ? 21.702  15.901  43.2    1 31.116 ? 25   VAL B CG1 1 
ATOM   4229 C  CG2 . VAL B 1 33  ? 21.221  18.281  42.609  1 33.057 ? 25   VAL B CG2 1 
ATOM   4230 N  N   . HIS B 1 34  ? 18.864  14.303  43.481  1 29.666 ? 26   HIS B N   1 
ATOM   4231 C  CA  . HIS B 1 34  ? 18.506  13.079  44.204  1 28.215 ? 26   HIS B CA  1 
ATOM   4232 C  C   . HIS B 1 34  ? 19.702  12.619  45.032  1 22.044 ? 26   HIS B C   1 
ATOM   4233 O  O   . HIS B 1 34  ? 20.723  12.32   44.455  1 24.718 ? 26   HIS B O   1 
ATOM   4234 C  CB  . HIS B 1 34  ? 17.971  11.941  43.3    1 26.98  ? 26   HIS B CB  1 
ATOM   4235 C  CG  . HIS B 1 34  ? 17.137  10.936  44.075  1 26.358 ? 26   HIS B CG  1 
ATOM   4236 N  ND1 . HIS B 1 34  ? 17.695  10.077  44.998  1 24.356 ? 26   HIS B ND1 1 
ATOM   4237 C  CD2 . HIS B 1 34  ? 15.802  10.734  44.166  1 27.207 ? 26   HIS B CD2 1 
ATOM   4238 C  CE1 . HIS B 1 34  ? 16.752  9.328   45.572  1 21.571 ? 26   HIS B CE1 1 
ATOM   4239 N  NE2 . HIS B 1 34  ? 15.605  9.714   45.087  1 23.639 ? 26   HIS B NE2 1 
ATOM   4240 N  N   . PRO B 1 35  ? 19.602  12.525  46.396  1 22.481 ? 27   PRO B N   1 
ATOM   4241 C  CA  . PRO B 1 35  ? 20.657  12.012  47.232  1 20.231 ? 27   PRO B CA  1 
ATOM   4242 C  C   . PRO B 1 35  ? 21.369  10.749  46.774  1 20.079 ? 27   PRO B C   1 
ATOM   4243 O  O   . PRO B 1 35  ? 22.568  10.613  46.98   1 18.592 ? 27   PRO B O   1 
ATOM   4244 C  CB  . PRO B 1 35  ? 20.053  11.886  48.661  1 21.533 ? 27   PRO B CB  1 
ATOM   4245 C  CG  . PRO B 1 35  ? 18.958  12.882  48.623  1 26.559 ? 27   PRO B CG  1 
ATOM   4246 C  CD  . PRO B 1 35  ? 18.458  12.986  47.199  1 24.871 ? 27   PRO B CD  1 
ATOM   4247 N  N   . THR B 1 36  ? 20.64   9.745   46.267  1 23.112 ? 28   THR B N   1 
ATOM   4248 C  CA  . THR B 1 36  ? 21.266  8.47    45.946  1 18.61  ? 28   THR B CA  1 
ATOM   4249 C  C   . THR B 1 36  ? 22.02   8.519   44.606  1 22.961 ? 28   THR B C   1 
ATOM   4250 O  O   . THR B 1 36  ? 22.811  7.617   44.333  1 25.092 ? 28   THR B O   1 
ATOM   4251 C  CB  . THR B 1 36  ? 20.29   7.286   45.939  1 21.697 ? 28   THR B CB  1 
ATOM   4252 O  OG1 . THR B 1 36  ? 19.416  7.494   44.838  1 21.994 ? 28   THR B OG1 1 
ATOM   4253 C  CG2 . THR B 1 36  ? 19.537  7.164   47.249  1 16.601 ? 28   THR B CG2 1 
ATOM   4254 N  N   . ASP B 1 37  ? 21.801  9.571   43.813  1 23.214 ? 29   ASP B N   1 
ATOM   4255 C  CA  . ASP B 1 37  ? 22.572  9.765   42.582  1 24.474 ? 29   ASP B CA  1 
ATOM   4256 C  C   . ASP B 1 37  ? 24.026  10.185  42.818  1 29.854 ? 29   ASP B C   1 
ATOM   4257 O  O   . ASP B 1 37  ? 24.865  10.104  41.889  1 21.749 ? 29   ASP B O   1 
ATOM   4258 C  CB  . ASP B 1 37  ? 21.848  10.702  41.656  1 26.401 ? 29   ASP B CB  1 
ATOM   4259 C  CG  . ASP B 1 37  ? 20.6    10.109  41.041  1 21.786 ? 29   ASP B CG  1 
ATOM   4260 O  OD1 . ASP B 1 37  ? 20.4    8.91    41.254  1 28.601 ? 29   ASP B OD1 1 
ATOM   4261 O  OD2 . ASP B 1 37  ? 19.792  10.895  40.56   1 21.963 ? 29   ASP B OD2 1 
ATOM   4262 N  N   . ILE B 1 38  ? 24.341  10.602  44.062  1 24.759 ? 30   ILE B N   1 
ATOM   4263 C  CA  . ILE B 1 38  ? 25.72   10.992  44.355  1 30.055 ? 30   ILE B CA  1 
ATOM   4264 C  C   . ILE B 1 38  ? 26.493  9.817   44.944  1 31.777 ? 30   ILE B C   1 
ATOM   4265 O  O   . ILE B 1 38  ? 27.696  9.925   45.148  1 28.454 ? 30   ILE B O   1 
ATOM   4266 C  CB  . ILE B 1 38  ? 25.889  12.333  45.107  1 29.676 ? 30   ILE B CB  1 
ATOM   4267 C  CG1 . ILE B 1 38  ? 25.446  12.242  46.577  1 29.11  ? 30   ILE B CG1 1 
ATOM   4268 C  CG2 . ILE B 1 38  ? 25.229  13.473  44.321  1 33.87  ? 30   ILE B CG2 1 
ATOM   4269 C  CD1 . ILE B 1 38  ? 26.198  13.121  47.564  1 30.961 ? 30   ILE B CD1 1 
ATOM   4270 N  N   . LEU B 1 39  ? 25.788  8.705   45.223  1 27.54  ? 31   LEU B N   1 
ATOM   4271 C  CA  . LEU B 1 39  ? 26.425  7.459   45.615  1 21.928 ? 31   LEU B CA  1 
ATOM   4272 C  C   . LEU B 1 39  ? 27.245  6.966   44.423  1 28.424 ? 31   LEU B C   1 
ATOM   4273 O  O   . LEU B 1 39  ? 26.772  7.088   43.28   1 25.998 ? 31   LEU B O   1 
ATOM   4274 C  CB  . LEU B 1 39  ? 25.478  6.356   46.114  1 22.444 ? 31   LEU B CB  1 
ATOM   4275 C  CG  . LEU B 1 39  ? 24.572  6.653   47.318  1 23.327 ? 31   LEU B CG  1 
ATOM   4276 C  CD1 . LEU B 1 39  ? 23.435  5.572   47.534  1 23.152 ? 31   LEU B CD1 1 
ATOM   4277 C  CD2 . LEU B 1 39  ? 25.31   6.874   48.68   1 26.722 ? 31   LEU B CD2 1 
ATOM   4278 N  N   . PRO B 1 40  ? 28.483  6.442   44.681  1 28.513 ? 32   PRO B N   1 
ATOM   4279 C  CA  . PRO B 1 40  ? 29.446  6.066   43.644  1 32.817 ? 32   PRO B CA  1 
ATOM   4280 C  C   . PRO B 1 40  ? 29.161  4.798   42.84   1 27.431 ? 32   PRO B C   1 
ATOM   4281 O  O   . PRO B 1 40  ? 28.787  3.765   43.382  1 25.515 ? 32   PRO B O   1 
ATOM   4282 C  CB  . PRO B 1 40  ? 30.762  5.992   44.424  1 32.824 ? 32   PRO B CB  1 
ATOM   4283 C  CG  . PRO B 1 40  ? 30.263  5.46    45.772  1 32.258 ? 32   PRO B CG  1 
ATOM   4284 C  CD  . PRO B 1 40  ? 29.081  6.33    46.032  1 25.605 ? 32   PRO B CD  1 
ATOM   4285 N  N   . SER B 1 41  ? 29.4    4.896   41.52   1 33.744 ? 33   SER B N   1 
ATOM   4286 C  CA  . SER B 1 41  ? 29.47   3.792   40.57   1 25.534 ? 33   SER B CA  1 
ATOM   4287 C  C   . SER B 1 41  ? 30.93   3.322   40.375  1 30.718 ? 33   SER B C   1 
ATOM   4288 O  O   . SER B 1 41  ? 31.908  4.119   40.315  1 22.917 ? 33   SER B O   1 
ATOM   4289 C  CB  . SER B 1 41  ? 28.924  4.288   39.254  1 29.64  ? 33   SER B CB  1 
ATOM   4290 O  OG  . SER B 1 41  ? 28.843  3.262   38.273  1 21.228 ? 33   SER B OG  1 
ATOM   4291 N  N   . GLY B 1 42  ? 31.034  1.999   40.182  1 22.356 ? 34   GLY B N   1 
ATOM   4292 C  CA  . GLY B 1 42  ? 32.25   1.308   39.819  1 21.656 ? 34   GLY B CA  1 
ATOM   4293 C  C   . GLY B 1 42  ? 32.292  1.055   38.306  1 24.265 ? 34   GLY B C   1 
ATOM   4294 O  O   . GLY B 1 42  ? 33.148  0.264   37.858  1 28.869 ? 34   GLY B O   1 
ATOM   4295 N  N   . TRP B 1 43  ? 31.368  1.702   37.548  1 19.34  ? 35   TRP B N   1 
ATOM   4296 C  CA  . TRP B 1 43  ? 31.348  1.577   36.09   1 17.611 ? 35   TRP B CA  1 
ATOM   4297 C  C   . TRP B 1 43  ? 32.177  2.663   35.423  1 19.33  ? 35   TRP B C   1 
ATOM   4298 O  O   . TRP B 1 43  ? 31.956  3.833   35.681  1 23.001 ? 35   TRP B O   1 
ATOM   4299 C  CB  . TRP B 1 43  ? 29.918  1.552   35.538  1 15.839 ? 35   TRP B CB  1 
ATOM   4300 C  CG  . TRP B 1 43  ? 29.341  0.161   35.526  1 16.205 ? 35   TRP B CG  1 
ATOM   4301 C  CD1 . TRP B 1 43  ? 28.802  -0.583  36.559  1 17.494 ? 35   TRP B CD1 1 
ATOM   4302 C  CD2 . TRP B 1 43  ? 29.196  -0.642  34.342  1 17.878 ? 35   TRP B CD2 1 
ATOM   4303 N  NE1 . TRP B 1 43  ? 28.373  -1.814  36.104  1 17.602 ? 35   TRP B NE1 1 
ATOM   4304 C  CE2 . TRP B 1 43  ? 28.607  -1.87   34.742  1 15.757 ? 35   TRP B CE2 1 
ATOM   4305 C  CE3 . TRP B 1 43  ? 29.509  -0.435  32.992  1 17.495 ? 35   TRP B CE3 1 
ATOM   4306 C  CZ2 . TRP B 1 43  ? 28.321  -2.865  33.811  1 19.023 ? 35   TRP B CZ2 1 
ATOM   4307 C  CZ3 . TRP B 1 43  ? 29.273  -1.452  32.084  1 19.996 ? 35   TRP B CZ3 1 
ATOM   4308 C  CH2 . TRP B 1 43  ? 28.623  -2.613  32.492  1 17.628 ? 35   TRP B CH2 1 
ATOM   4309 N  N   . PRO B 1 44  ? 33.104  2.323   34.491  1 17.433 ? 36   PRO B N   1 
ATOM   4310 C  CA  . PRO B 1 44  ? 33.61   3.318   33.543  1 18.968 ? 36   PRO B CA  1 
ATOM   4311 C  C   . PRO B 1 44  ? 32.535  3.712   32.521  1 22.13  ? 36   PRO B C   1 
ATOM   4312 O  O   . PRO B 1 44  ? 31.499  3.051   32.367  1 19.199 ? 36   PRO B O   1 
ATOM   4313 C  CB  . PRO B 1 44  ? 34.846  2.643   32.941  1 17.6   ? 36   PRO B CB  1 
ATOM   4314 C  CG  . PRO B 1 44  ? 34.284  1.229   32.811  1 17.61  ? 36   PRO B CG  1 
ATOM   4315 C  CD  . PRO B 1 44  ? 33.577  0.964   34.176  1 17.747 ? 36   PRO B CD  1 
ATOM   4316 N  N   . THR B 1 45  ? 32.758  4.827   31.846  1 21.651 ? 37   THR B N   1 
ATOM   4317 C  CA  . THR B 1 45  ? 31.892  5.206   30.753  1 21.788 ? 37   THR B CA  1 
ATOM   4318 C  C   . THR B 1 45  ? 32.019  4.17    29.639  1 20.389 ? 37   THR B C   1 
ATOM   4319 O  O   . THR B 1 45  ? 33.079  4.06    29.019  1 21.146 ? 37   THR B O   1 
ATOM   4320 C  CB  . THR B 1 45  ? 32.155  6.624   30.268  1 21.462 ? 37   THR B CB  1 
ATOM   4321 O  OG1 . THR B 1 45  ? 32.003  7.321   31.496  1 23.772 ? 37   THR B OG1 1 
ATOM   4322 C  CG2 . THR B 1 45  ? 31.06   7.057   29.309  1 18.177 ? 37   THR B CG2 1 
ATOM   4323 N  N   . ALA B 1 46  ? 30.926  3.414   29.431  1 15.803 ? 38   ALA B N   1 
ATOM   4324 C  CA  . ALA B 1 46  ? 30.939  2.403   28.375  1 19.413 ? 38   ALA B CA  1 
ATOM   4325 C  C   . ALA B 1 46  ? 30.007  2.81    27.223  1 19.882 ? 38   ALA B C   1 
ATOM   4326 O  O   . ALA B 1 46  ? 28.812  2.552   27.265  1 17.803 ? 38   ALA B O   1 
ATOM   4327 C  CB  . ALA B 1 46  ? 30.577  1.052   28.99   1 21.898 ? 38   ALA B CB  1 
ATOM   4328 N  N   . THR B 1 47  ? 30.546  3.52    26.215  1 18.856 ? 39   THR B N   1 
ATOM   4329 C  CA  . THR B 1 47  ? 29.7    4.068   25.175  1 16.976 ? 39   THR B CA  1 
ATOM   4330 C  C   . THR B 1 47  ? 29.426  2.996   24.103  1 16.967 ? 39   THR B C   1 
ATOM   4331 O  O   . THR B 1 47  ? 30.167  2.023   23.998  1 18.149 ? 39   THR B O   1 
ATOM   4332 C  CB  . THR B 1 47  ? 30.267  5.357   24.533  1 19.855 ? 39   THR B CB  1 
ATOM   4333 O  OG1 . THR B 1 47  ? 31.295  4.937   23.62   1 18.003 ? 39   THR B OG1 1 
ATOM   4334 C  CG2 . THR B 1 47  ? 30.596  6.426   25.571  1 16.227 ? 39   THR B CG2 1 
ATOM   4335 N  N   . ASP B 1 48  ? 28.334  3.186   23.365  1 15.009 ? 40   ASP B N   1 
ATOM   4336 C  CA  . ASP B 1 48  ? 28.118  2.477   22.105  1 14.266 ? 40   ASP B CA  1 
ATOM   4337 C  C   . ASP B 1 48  ? 28.351  3.471   20.974  1 12.721 ? 40   ASP B C   1 
ATOM   4338 O  O   . ASP B 1 48  ? 28.61   4.667   21.216  1 15.393 ? 40   ASP B O   1 
ATOM   4339 C  CB  . ASP B 1 48  ? 26.774  1.726   22.063  1 13.608 ? 40   ASP B CB  1 
ATOM   4340 C  CG  . ASP B 1 48  ? 25.603  2.699   22.21   1 17.407 ? 40   ASP B CG  1 
ATOM   4341 O  OD1 . ASP B 1 48  ? 25.517  3.665   21.432  1 15.035 ? 40   ASP B OD1 1 
ATOM   4342 O  OD2 . ASP B 1 48  ? 24.78   2.519   23.112  1 17.722 ? 40   ASP B OD2 1 
ATOM   4343 N  N   . LEU B 1 49  ? 28.206  3.016   19.706  1 13.799 ? 41   LEU B N   1 
ATOM   4344 C  CA  . LEU B 1 49  ? 28.585  3.896   18.589  1 13.163 ? 41   LEU B CA  1 
ATOM   4345 C  C   . LEU B 1 49  ? 27.837  5.217   18.587  1 15.494 ? 41   LEU B C   1 
ATOM   4346 O  O   . LEU B 1 49  ? 28.325  6.168   17.99   1 17.699 ? 41   LEU B O   1 
ATOM   4347 C  CB  . LEU B 1 49  ? 28.42   3.187   17.222  1 13.715 ? 41   LEU B CB  1 
ATOM   4348 C  CG  . LEU B 1 49  ? 29.679  2.435   16.744  1 16.244 ? 41   LEU B CG  1 
ATOM   4349 C  CD1 . LEU B 1 49  ? 29.314  1.886   15.357  1 17.537 ? 41   LEU B CD1 1 
ATOM   4350 C  CD2 . LEU B 1 49  ? 30.909  3.363   16.669  1 17.483 ? 41   LEU B CD2 1 
ATOM   4351 N  N   . SER B 1 50  ? 26.571  5.188   19.069  1 14.821 ? 42   SER B N   1 
ATOM   4352 C  CA  . SER B 1 50  ? 25.676  6.338   19.068  1 14.65  ? 42   SER B CA  1 
ATOM   4353 C  C   . SER B 1 50  ? 26.172  7.416   20.024  1 16.963 ? 42   SER B C   1 
ATOM   4354 O  O   . SER B 1 50  ? 25.813  8.59    19.894  1 18.84  ? 42   SER B O   1 
ATOM   4355 C  CB  . SER B 1 50  ? 24.231  5.894   19.376  1 16.456 ? 42   SER B CB  1 
ATOM   4356 O  OG  . SER B 1 50  ? 24.013  5.704   20.775  1 17.089 ? 42   SER B OG  1 
ATOM   4357 N  N   . GLY B 1 51  ? 26.939  6.987   21.021  1 16.494 ? 43   GLY B N   1 
ATOM   4358 C  CA  . GLY B 1 51  ? 27.461  7.872   22.042  1 16.608 ? 43   GLY B CA  1 
ATOM   4359 C  C   . GLY B 1 51  ? 26.746  7.617   23.348  1 16.089 ? 43   GLY B C   1 
ATOM   4360 O  O   . GLY B 1 51  ? 27.207  8.084   24.401  1 18.914 ? 43   GLY B O   1 
ATOM   4361 N  N   . GLY B 1 52  ? 25.694  6.768   23.275  1 18.107 ? 44   GLY B N   1 
ATOM   4362 C  CA  . GLY B 1 52  ? 24.887  6.417   24.433  1 18.291 ? 44   GLY B CA  1 
ATOM   4363 C  C   . GLY B 1 52  ? 25.749  5.661   25.429  1 20.118 ? 44   GLY B C   1 
ATOM   4364 O  O   . GLY B 1 52  ? 26.57   4.836   25.012  1 17.312 ? 44   GLY B O   1 
ATOM   4365 N  N   . ALA B 1 53  ? 25.521  5.892   26.731  1 18.233 ? 45   ALA B N   1 
ATOM   4366 C  CA  . ALA B 1 53  ? 26.405  5.245   27.682  1 20.361 ? 45   ALA B CA  1 
ATOM   4367 C  C   . ALA B 1 53  ? 25.654  4.402   28.733  1 22.435 ? 45   ALA B C   1 
ATOM   4368 O  O   . ALA B 1 53  ? 26.208  4.145   29.81   1 22.442 ? 45   ALA B O   1 
ATOM   4369 C  CB  . ALA B 1 53  ? 27.3    6.304   28.323  1 27.299 ? 45   ALA B CB  1 
ATOM   4370 N  N   . GLN B 1 54  ? 24.397  4.036   28.485  1 18.366 ? 46   GLN B N   1 
ATOM   4371 C  CA  . GLN B 1 54  ? 23.695  3.335   29.542  1 19.169 ? 46   GLN B CA  1 
ATOM   4372 C  C   . GLN B 1 54  ? 23.823  1.82    29.329  1 16.975 ? 46   GLN B C   1 
ATOM   4373 O  O   . GLN B 1 54  ? 23.282  1.329   28.311  1 15.44  ? 46   GLN B O   1 
ATOM   4374 C  CB  . GLN B 1 54  ? 22.238  3.826   29.688  1 20.317 ? 46   GLN B CB  1 
ATOM   4375 C  CG  . GLN B 1 54  ? 21.417  2.972   30.651  1 29.079 ? 46   GLN B CG  1 
ATOM   4376 C  CD  . GLN B 1 54  ? 21.858  3.006   32.111  1 33.911 ? 46   GLN B CD  1 
ATOM   4377 O  OE1 . GLN B 1 54  ? 22.061  4.095   32.665  1 32.76  ? 46   GLN B OE1 1 
ATOM   4378 N  NE2 . GLN B 1 54  ? 21.994  1.841   32.76   1 22.217 ? 46   GLN B NE2 1 
ATOM   4379 N  N   . PRO B 1 55  ? 24.464  1.035   30.257  1 17.079 ? 47   PRO B N   1 
ATOM   4380 C  CA  . PRO B 1 55  ? 24.406  -0.428  30.182  1 14.865 ? 47   PRO B CA  1 
ATOM   4381 C  C   . PRO B 1 55  ? 22.959  -0.913  30.245  1 15.356 ? 47   PRO B C   1 
ATOM   4382 O  O   . PRO B 1 55  ? 22.22   -0.353  31.065  1 14.842 ? 47   PRO B O   1 
ATOM   4383 C  CB  . PRO B 1 55  ? 25.102  -0.874  31.473  1 14.091 ? 47   PRO B CB  1 
ATOM   4384 C  CG  . PRO B 1 55  ? 26.161  0.242   31.656  1 16.174 ? 47   PRO B CG  1 
ATOM   4385 C  CD  . PRO B 1 55  ? 25.342  1.486   31.352  1 15.588 ? 47   PRO B CD  1 
ATOM   4386 N  N   . ARG B 1 56  ? 22.615  -1.951  29.447  1 14.256 ? 48   ARG B N   1 
ATOM   4387 C  CA  . ARG B 1 56  ? 21.289  -2.538  29.473  1 14.741 ? 48   ARG B CA  1 
ATOM   4388 C  C   . ARG B 1 56  ? 21.407  -3.97   30.019  1 15.881 ? 48   ARG B C   1 
ATOM   4389 O  O   . ARG B 1 56  ? 21.18   -4.164  31.201  1 14.84  ? 48   ARG B O   1 
ATOM   4390 C  CB  . ARG B 1 56  ? 20.614  -2.406  28.101  1 15.305 ? 48   ARG B CB  1 
ATOM   4391 C  CG  . ARG B 1 56  ? 20.497  -0.975  27.586  1 15.892 ? 48   ARG B CG  1 
ATOM   4392 C  CD  . ARG B 1 56  ? 19.605  -0.165  28.438  1 13.567 ? 48   ARG B CD  1 
ATOM   4393 N  NE  . ARG B 1 56  ? 19.546  1.202   27.946  1 14.218 ? 48   ARG B NE  1 
ATOM   4394 C  CZ  . ARG B 1 56  ? 18.913  2.217   28.48   1 20.286 ? 48   ARG B CZ  1 
ATOM   4395 N  NH1 . ARG B 1 56  ? 18.166  2.095   29.564  1 16.764 ? 48   ARG B NH1 1 
ATOM   4396 N  NH2 . ARG B 1 56  ? 19.04   3.409   27.882  1 22.497 ? 48   ARG B NH2 1 
ATOM   4397 N  N   . ARG B 1 57  ? 21.92   -4.892  29.197  1 13.241 ? 49   ARG B N   1 
ATOM   4398 C  CA  . ARG B 1 57  ? 22.414  -6.214  29.576  1 13.077 ? 49   ARG B CA  1 
ATOM   4399 C  C   . ARG B 1 57  ? 21.274  -7.173  29.952  1 14.954 ? 49   ARG B C   1 
ATOM   4400 O  O   . ARG B 1 57  ? 21.499  -8.225  30.565  1 17.638 ? 49   ARG B O   1 
ATOM   4401 C  CB  . ARG B 1 57  ? 23.493  -6.227  30.682  1 11.493 ? 49   ARG B CB  1 
ATOM   4402 C  CG  . ARG B 1 57  ? 24.523  -5.094  30.471  1 12.881 ? 49   ARG B CG  1 
ATOM   4403 C  CD  . ARG B 1 57  ? 25.493  -4.938  31.632  1 13.69  ? 49   ARG B CD  1 
ATOM   4404 N  NE  . ARG B 1 57  ? 24.81   -4.544  32.859  1 14.599 ? 49   ARG B NE  1 
ATOM   4405 C  CZ  . ARG B 1 57  ? 25.004  -4.999  34.101  1 15.884 ? 49   ARG B CZ  1 
ATOM   4406 N  NH1 . ARG B 1 57  ? 25.923  -5.907  34.368  1 15.087 ? 49   ARG B NH1 1 
ATOM   4407 N  NH2 . ARG B 1 57  ? 24.258  -4.519  35.066  1 14.205 ? 49   ARG B NH2 1 
ATOM   4408 N  N   . PHE B 1 58  ? 20.068  -6.877  29.511  1 17.643 ? 50   PHE B N   1 
ATOM   4409 C  CA  . PHE B 1 58  ? 18.977  -7.809  29.853  1 18.934 ? 50   PHE B CA  1 
ATOM   4410 C  C   . PHE B 1 58  ? 19.006  -9.006  28.922  1 15.735 ? 50   PHE B C   1 
ATOM   4411 O  O   . PHE B 1 58  ? 19.31   -8.882  27.694  1 14.756 ? 50   PHE B O   1 
ATOM   4412 C  CB  . PHE B 1 58  ? 17.633  -7.09   29.825  1 27.159 ? 50   PHE B CB  1 
ATOM   4413 C  CG  . PHE B 1 58  ? 17.559  -5.98   28.792  1 39.085 ? 50   PHE B CG  1 
ATOM   4414 C  CD1 . PHE B 1 58  ? 16.79   -4.836  29.03   1 43.631 ? 50   PHE B CD1 1 
ATOM   4415 C  CD2 . PHE B 1 58  ? 18.326  -6.017  27.618  1 50.373 ? 50   PHE B CD2 1 
ATOM   4416 C  CE1 . PHE B 1 58  ? 16.722  -3.808  28.088  1 26.47  ? 50   PHE B CE1 1 
ATOM   4417 C  CE2 . PHE B 1 58  ? 18.332  -4.961  26.726  1 39.849 ? 50   PHE B CE2 1 
ATOM   4418 C  CZ  . PHE B 1 58  ? 17.492  -3.876  26.95   1 47.915 ? 50   PHE B CZ  1 
ATOM   4419 N  N   . GLU B 1 59  ? 18.625  -10.16  29.509  1 15.738 ? 51   GLU B N   1 
ATOM   4420 C  CA  . GLU B 1 59  ? 18.508  -11.355 28.686  1 13.47  ? 51   GLU B CA  1 
ATOM   4421 C  C   . GLU B 1 59  ? 17.152  -11.952 28.99   1 14.378 ? 51   GLU B C   1 
ATOM   4422 O  O   . GLU B 1 59  ? 16.882  -12.323 30.137  1 12.541 ? 51   GLU B O   1 
ATOM   4423 C  CB  . GLU B 1 59  ? 19.624  -12.393 28.856  1 13.004 ? 51   GLU B CB  1 
ATOM   4424 C  CG  . GLU B 1 59  ? 21.051  -11.792 28.814  1 14.179 ? 51   GLU B CG  1 
ATOM   4425 C  CD  . GLU B 1 59  ? 22.051  -12.939 28.93   1 12.505 ? 51   GLU B CD  1 
ATOM   4426 O  OE1 . GLU B 1 59  ? 22.341  -13.351 30.087  1 11.688 ? 51   GLU B OE1 1 
ATOM   4427 O  OE2 . GLU B 1 59  ? 22.524  -13.49  27.939  1 9.486  ? 51   GLU B OE2 1 
ATOM   4428 N  N   . GLY B 1 60  ? 16.361  -12.101 27.93   1 10.78  ? 52   GLY B N   1 
ATOM   4429 C  CA  . GLY B 1 60  ? 14.993  -12.52  28.178  1 12.563 ? 52   GLY B CA  1 
ATOM   4430 C  C   . GLY B 1 60  ? 14.042  -12.179 27.04   1 15.702 ? 52   GLY B C   1 
ATOM   4431 O  O   . GLY B 1 60  ? 14.517  -11.946 25.92   1 14.907 ? 52   GLY B O   1 
ATOM   4432 N  N   . THR B 1 61  ? 12.719  -12.347 27.33   1 15.326 ? 53   THR B N   1 
ATOM   4433 C  CA  . THR B 1 61  ? 11.718  -12.26  26.26   1 13.641 ? 53   THR B CA  1 
ATOM   4434 C  C   . THR B 1 61  ? 10.57   -11.343 26.669  1 13.463 ? 53   THR B C   1 
ATOM   4435 O  O   . THR B 1 61  ? 10.35   -11.05  27.873  1 11.513 ? 53   THR B O   1 
ATOM   4436 C  CB  . THR B 1 61  ? 11.175  -13.649 25.934  1 13.194 ? 53   THR B CB  1 
ATOM   4437 O  OG1 . THR B 1 61  ? 10.696  -14.2   27.17   1 13.505 ? 53   THR B OG1 1 
ATOM   4438 C  CG2 . THR B 1 61  ? 12.242  -14.531 25.305  1 13.349 ? 53   THR B CG2 1 
ATOM   4439 N  N   . ILE B 1 62  ? 9.794   -11.025 25.634  1 11.573 ? 54   ILE B N   1 
ATOM   4440 C  CA  . ILE B 1 62  ? 8.442   -10.487 25.749  1 14.922 ? 54   ILE B CA  1 
ATOM   4441 C  C   . ILE B 1 62  ? 7.574   -11.185 24.69   1 15.338 ? 54   ILE B C   1 
ATOM   4442 O  O   . ILE B 1 62  ? 7.889   -11.13  23.484  1 17.409 ? 54   ILE B O   1 
ATOM   4443 C  CB  . ILE B 1 62  ? 8.428   -8.959  25.5    1 13.846 ? 54   ILE B CB  1 
ATOM   4444 C  CG1 . ILE B 1 62  ? 9.271   -8.215  26.53   1 17.487 ? 54   ILE B CG1 1 
ATOM   4445 C  CG2 . ILE B 1 62  ? 6.968   -8.446  25.549  1 10.98  ? 54   ILE B CG2 1 
ATOM   4446 C  CD1 . ILE B 1 62  ? 9.507   -6.761  26.178  1 15.284 ? 54   ILE B CD1 1 
ATOM   4447 N  N   . PHE B 1 63  ? 6.477   -11.792 25.139  1 14.445 ? 55   PHE B N   1 
ATOM   4448 C  CA  . PHE B 1 63  ? 5.572   -12.455 24.207  1 15.338 ? 55   PHE B CA  1 
ATOM   4449 C  C   . PHE B 1 63  ? 4.514   -11.443 23.797  1 14.623 ? 55   PHE B C   1 
ATOM   4450 O  O   . PHE B 1 63  ? 3.909   -10.812 24.647  1 15.327 ? 55   PHE B O   1 
ATOM   4451 C  CB  . PHE B 1 63  ? 4.929   -13.648 24.933  1 16.531 ? 55   PHE B CB  1 
ATOM   4452 C  CG  . PHE B 1 63  ? 3.896   -14.356 24.088  1 17.878 ? 55   PHE B CG  1 
ATOM   4453 C  CD1 . PHE B 1 63  ? 4.284   -15.34  23.168  1 18.63  ? 55   PHE B CD1 1 
ATOM   4454 C  CD2 . PHE B 1 63  ? 2.537   -14.083 24.264  1 16.789 ? 55   PHE B CD2 1 
ATOM   4455 C  CE1 . PHE B 1 63  ? 3.322   -16.023 22.417  1 17.691 ? 55   PHE B CE1 1 
ATOM   4456 C  CE2 . PHE B 1 63  ? 1.592   -14.722 23.48   1 17.7   ? 55   PHE B CE2 1 
ATOM   4457 C  CZ  . PHE B 1 63  ? 1.985   -15.671 22.538  1 18.232 ? 55   PHE B CZ  1 
ATOM   4458 N  N   . ASP B 1 64  ? 4.248   -11.287 22.483  1 15.991 ? 56   ASP B N   1 
ATOM   4459 C  CA  . ASP B 1 64  ? 3.196   -10.357 22.113  1 14.286 ? 56   ASP B CA  1 
ATOM   4460 C  C   . ASP B 1 64  ? 3.571   -8.917  22.518  1 16.103 ? 56   ASP B C   1 
ATOM   4461 O  O   . ASP B 1 64  ? 2.809   -8.236  23.266  1 16.296 ? 56   ASP B O   1 
ATOM   4462 C  CB  . ASP B 1 64  ? 1.801   -10.8   22.561  1 16.932 ? 56   ASP B CB  1 
ATOM   4463 C  CG  . ASP B 1 64  ? 0.673   -10.374 21.629  1 16.738 ? 56   ASP B CG  1 
ATOM   4464 O  OD1 . ASP B 1 64  ? 0.97    -9.822  20.568  1 16.563 ? 56   ASP B OD1 1 
ATOM   4465 O  OD2 . ASP B 1 64  ? -0.452  -10.615 21.931  1 16.544 ? 56   ASP B OD2 1 
ATOM   4466 N  N   . VAL B 1 65  ? 4.74    -8.475  22.026  1 15.135 ? 57   VAL B N   1 
ATOM   4467 C  CA  . VAL B 1 65  ? 5.226   -7.092  22.173  1 16.335 ? 57   VAL B CA  1 
ATOM   4468 C  C   . VAL B 1 65  ? 4.14    -6.075  21.781  1 17.868 ? 57   VAL B C   1 
ATOM   4469 O  O   . VAL B 1 65  ? 3.484   -6.244  20.769  1 17.807 ? 57   VAL B O   1 
ATOM   4470 C  CB  . VAL B 1 65  ? 6.582   -6.8    21.473  1 13.683 ? 57   VAL B CB  1 
ATOM   4471 C  CG1 . VAL B 1 65  ? 7.18    -5.453  21.853  1 14.258 ? 57   VAL B CG1 1 
ATOM   4472 C  CG2 . VAL B 1 65  ? 7.629   -7.859  21.738  1 11.931 ? 57   VAL B CG2 1 
ATOM   4473 N  N   . MET B 1 66  ? 3.966   -5.014  22.588  1 16.04  ? 58   MET B N   1 
ATOM   4474 C  CA  . MET B 1 66  ? 2.966   -4.003  22.269  1 16.334 ? 58   MET B CA  1 
ATOM   4475 C  C   . MET B 1 66  ? 3.244   -3.357  20.91   1 15.023 ? 58   MET B C   1 
ATOM   4476 O  O   . MET B 1 66  ? 4.381   -3.074  20.608  1 17.301 ? 58   MET B O   1 
ATOM   4477 C  CB  . MET B 1 66  ? 2.944   -2.953  23.375  1 19.406 ? 58   MET B CB  1 
ATOM   4478 C  CG  . MET B 1 66  ? 1.929   -1.869  23.087  1 21.705 ? 58   MET B CG  1 
ATOM   4479 S  SD  . MET B 1 66  ? 1.823   -0.555  24.321  1 34.086 ? 58   MET B SD  1 
ATOM   4480 C  CE  . MET B 1 66  ? 1.592   -1.606  25.763  1 21.284 ? 58   MET B CE  1 
ATOM   4481 N  N   . THR B 1 67  ? 2.226   -3.246  20.051  1 16.075 ? 59   THR B N   1 
ATOM   4482 C  CA  . THR B 1 67  ? 2.397   -2.607  18.746  1 18.205 ? 59   THR B CA  1 
ATOM   4483 C  C   . THR B 1 67  ? 1.364   -1.478  18.606  1 23.351 ? 59   THR B C   1 
ATOM   4484 O  O   . THR B 1 67  ? 0.228   -1.596  19.066  1 25.868 ? 59   THR B O   1 
ATOM   4485 C  CB  . THR B 1 67  ? 2.366   -3.611  17.603  1 17.308 ? 59   THR B CB  1 
ATOM   4486 O  OG1 . THR B 1 67  ? 1.071   -4.235  17.642  1 22.813 ? 59   THR B OG1 1 
ATOM   4487 C  CG2 . THR B 1 67  ? 3.443   -4.699  17.674  1 16.407 ? 59   THR B CG2 1 
ATOM   4488 N  N   . ARG B 1 68  ? 1.812   -0.322  18.069  1 21.738 ? 60   ARG B N   1 
ATOM   4489 C  CA  . ARG B 1 68  ? 0.898   0.754   17.694  1 20.421 ? 60   ARG B CA  1 
ATOM   4490 C  C   . ARG B 1 68  ? 0.713   0.644   16.174  1 21.213 ? 60   ARG B C   1 
ATOM   4491 O  O   . ARG B 1 68  ? 1.689   0.517   15.451  1 14.622 ? 60   ARG B O   1 
ATOM   4492 C  CB  . ARG B 1 68  ? 1.402   2.113   18.182  1 21     ? 60   ARG B CB  1 
ATOM   4493 C  CG  . ARG B 1 68  ? 1.505   2.271   19.705  1 26.921 ? 60   ARG B CG  1 
ATOM   4494 C  CD  . ARG B 1 68  ? 1.916   3.722   20.089  1 28.632 ? 60   ARG B CD  1 
ATOM   4495 N  NE  . ARG B 1 68  ? 3.031   4.406   19.391  1 31.702 ? 60   ARG B NE  1 
ATOM   4496 C  CZ  . ARG B 1 68  ? 4.356   4.171   19.536  1 31.287 ? 60   ARG B CZ  1 
ATOM   4497 N  NH1 . ARG B 1 68  ? 4.726   3.343   20.5    1 21.596 ? 60   ARG B NH1 1 
ATOM   4498 N  NH2 . ARG B 1 68  ? 5.29    4.843   18.828  1 25.503 ? 60   ARG B NH2 1 
ATOM   4499 N  N   . GLY B 1 69  ? -0.561  0.602   15.732  1 20.443 ? 61   GLY B N   1 
ATOM   4500 C  CA  . GLY B 1 69  ? -0.898  0.508   14.326  1 22.413 ? 61   GLY B CA  1 
ATOM   4501 C  C   . GLY B 1 69  ? -0.882  -0.953  13.914  1 24.047 ? 61   GLY B C   1 
ATOM   4502 O  O   . GLY B 1 69  ? -0.717  -1.862  14.736  1 28.453 ? 61   GLY B O   1 
ATOM   4503 N  N   . THR B 1 70  ? -0.946  -1.195  12.602  1 29.134 ? 62   THR B N   1 
ATOM   4504 C  CA  . THR B 1 70  ? -1.216  -2.551  12.166  1 29.362 ? 62   THR B CA  1 
ATOM   4505 C  C   . THR B 1 70  ? 0.074   -3.14   11.608  1 26.514 ? 62   THR B C   1 
ATOM   4506 O  O   . THR B 1 70  ? 0.638   -2.548  10.694  1 27.88  ? 62   THR B O   1 
ATOM   4507 C  CB  . THR B 1 70  ? -2.401  -2.569  11.193  1 32.685 ? 62   THR B CB  1 
ATOM   4508 O  OG1 . THR B 1 70  ? -3.529  -2.603  12.06   1 35.072 ? 62   THR B OG1 1 
ATOM   4509 C  CG2 . THR B 1 70  ? -2.471  -3.867  10.419  1 25.765 ? 62   THR B CG2 1 
ATOM   4510 N  N   . ILE B 1 71  ? 0.471   -4.313  12.148  1 22.379 ? 63   ILE B N   1 
ATOM   4511 C  CA  . ILE B 1 71  ? 1.673   -5.019  11.676  1 19.532 ? 63   ILE B CA  1 
ATOM   4512 C  C   . ILE B 1 71  ? 1.33    -5.68   10.348  1 17.868 ? 63   ILE B C   1 
ATOM   4513 O  O   . ILE B 1 71  ? 0.399   -6.491  10.302  1 20.356 ? 63   ILE B O   1 
ATOM   4514 C  CB  . ILE B 1 71  ? 2.147   -6.036  12.706  1 16.369 ? 63   ILE B CB  1 
ATOM   4515 C  CG1 . ILE B 1 71  ? 2.591   -5.292  14.001  1 19.75  ? 63   ILE B CG1 1 
ATOM   4516 C  CG2 . ILE B 1 71  ? 3.21    -7.036  12.141  1 17.185 ? 63   ILE B CG2 1 
ATOM   4517 C  CD1 . ILE B 1 71  ? 3.839   -4.422  13.855  1 18.667 ? 63   ILE B CD1 1 
ATOM   4518 N  N   . PRO B 1 72  ? 2.048   -5.369  9.248   1 17.966 ? 64   PRO B N   1 
ATOM   4519 C  CA  . PRO B 1 72  ? 1.647   -5.943  7.96    1 18.321 ? 64   PRO B CA  1 
ATOM   4520 C  C   . PRO B 1 72  ? 1.716   -7.464  7.992   1 23.523 ? 64   PRO B C   1 
ATOM   4521 O  O   . PRO B 1 72  ? 2.664   -8.052  8.499   1 18.796 ? 64   PRO B O   1 
ATOM   4522 C  CB  . PRO B 1 72  ? 2.643   -5.364  6.982   1 23.856 ? 64   PRO B CB  1 
ATOM   4523 C  CG  . PRO B 1 72  ? 3.265   -4.16   7.658   1 21.525 ? 64   PRO B CG  1 
ATOM   4524 C  CD  . PRO B 1 72  ? 3.158   -4.4    9.161   1 16.6   ? 64   PRO B CD  1 
ATOM   4525 N  N   . LYS B 1 73  ? 0.664   -8.118  7.499   1 24.395 ? 65   LYS B N   1 
ATOM   4526 C  CA  . LYS B 1 73  ? 0.601   -9.571  7.401   1 27.949 ? 65   LYS B CA  1 
ATOM   4527 C  C   . LYS B 1 73  ? 1.708   -10.138 6.514   1 24.017 ? 65   LYS B C   1 
ATOM   4528 O  O   . LYS B 1 73  ? 2.082   -11.312 6.645   1 20.476 ? 65   LYS B O   1 
ATOM   4529 C  CB  . LYS B 1 73  ? -0.791  -10.058 6.996   1 36.405 ? 65   LYS B CB  1 
ATOM   4530 C  CG  . LYS B 1 73  ? -1.76   -10.272 8.171   1 48.134 ? 65   LYS B CG  1 
ATOM   4531 C  CD  . LYS B 1 73  ? -1.482  -11.299 9.274   1 44.619 ? 65   LYS B CD  1 
ATOM   4532 C  CE  . LYS B 1 73  ? -1.396  -12.715 8.751   1 53.902 ? 65   LYS B CE  1 
ATOM   4533 N  NZ  . LYS B 1 73  ? -2.634  -13.273 8.19    1 53.528 ? 65   LYS B NZ  1 
ATOM   4534 N  N   . GLU B 1 74  ? 2.358   -9.267  5.746   1 21.697 ? 66   GLU B N   1 
ATOM   4535 C  CA  . GLU B 1 74  ? 3.388   -9.749  4.821   1 21.475 ? 66   GLU B CA  1 
ATOM   4536 C  C   . GLU B 1 74  ? 4.711   -9.987  5.53    1 20.363 ? 66   GLU B C   1 
ATOM   4537 O  O   . GLU B 1 74  ? 5.549   -10.682 4.999   1 16.819 ? 66   GLU B O   1 
ATOM   4538 C  CB  . GLU B 1 74  ? 3.73    -8.797  3.68    1 24.975 ? 66   GLU B CB  1 
ATOM   4539 C  CG  . GLU B 1 74  ? 2.526   -8.597  2.759   1 25.128 ? 66   GLU B CG  1 
ATOM   4540 C  CD  . GLU B 1 74  ? 1.473   -7.589  3.208   1 31.71  ? 66   GLU B CD  1 
ATOM   4541 O  OE1 . GLU B 1 74  ? 1.417   -7.011  4.341   1 27.084 ? 66   GLU B OE1 1 
ATOM   4542 O  OE2 . GLU B 1 74  ? 0.636   -7.392  2.307   1 28.942 ? 66   GLU B OE2 1 
ATOM   4543 N  N   . LEU B 1 75  ? 4.864   -9.461  6.76    1 21.676 ? 67   LEU B N   1 
ATOM   4544 C  CA  . LEU B 1 75  ? 6.093   -9.753  7.484   1 16.069 ? 67   LEU B CA  1 
ATOM   4545 C  C   . LEU B 1 75  ? 6.007   -11.167 8.015   1 17.28  ? 67   LEU B C   1 
ATOM   4546 O  O   . LEU B 1 75  ? 5.086   -11.52  8.759   1 20.915 ? 67   LEU B O   1 
ATOM   4547 C  CB  . LEU B 1 75  ? 6.332   -8.677  8.538   1 17.903 ? 67   LEU B CB  1 
ATOM   4548 C  CG  . LEU B 1 75  ? 6.671   -7.275  7.986   1 16.912 ? 67   LEU B CG  1 
ATOM   4549 C  CD1 . LEU B 1 75  ? 6.55    -6.351  9.248   1 13.995 ? 67   LEU B CD1 1 
ATOM   4550 C  CD2 . LEU B 1 75  ? 8.08    -7.164  7.375   1 18.894 ? 67   LEU B CD2 1 
ATOM   4551 N  N   . HIS B 1 76  ? 6.985   -12.002 7.618   1 18.727 ? 68   HIS B N   1 
ATOM   4552 C  CA  . HIS B 1 76  ? 7.024   -13.401 8.035   1 16.772 ? 68   HIS B CA  1 
ATOM   4553 C  C   . HIS B 1 76  ? 8.487   -13.824 8.185   1 14.758 ? 68   HIS B C   1 
ATOM   4554 O  O   . HIS B 1 76  ? 9.13    -14.319 7.268   1 12.964 ? 68   HIS B O   1 
ATOM   4555 C  CB  . HIS B 1 76  ? 6.283   -14.287 7.017   1 21.856 ? 68   HIS B CB  1 
ATOM   4556 C  CG  . HIS B 1 76  ? 6.052   -15.689 7.436   1 20.035 ? 68   HIS B CG  1 
ATOM   4557 N  ND1 . HIS B 1 76  ? 5.003   -16.034 8.257   1 22.586 ? 68   HIS B ND1 1 
ATOM   4558 C  CD2 . HIS B 1 76  ? 6.687   -16.825 7.133   1 20.543 ? 68   HIS B CD2 1 
ATOM   4559 C  CE1 . HIS B 1 76  ? 5.008   -17.347 8.443   1 20.507 ? 68   HIS B CE1 1 
ATOM   4560 N  NE2 . HIS B 1 76  ? 6.018   -17.839 7.779   1 19.904 ? 68   HIS B NE2 1 
ATOM   4561 N  N   . GLY B 1 77  ? 9.026   -13.639 9.389   1 13.51  ? 69   GLY B N   1 
ATOM   4562 C  CA  . GLY B 1 77  ? 10.484  -13.636 9.533   1 13.649 ? 69   GLY B CA  1 
ATOM   4563 C  C   . GLY B 1 77  ? 10.931  -12.925 10.828  1 14.861 ? 69   GLY B C   1 
ATOM   4564 O  O   . GLY B 1 77  ? 10.109  -12.655 11.694  1 14.347 ? 69   GLY B O   1 
ATOM   4565 N  N   . THR B 1 78  ? 12.233  -12.647 10.948  1 14.353 ? 70   THR B N   1 
ATOM   4566 C  CA  . THR B 1 78  ? 12.783  -12.167 12.209  1 13.793 ? 70   THR B CA  1 
ATOM   4567 C  C   . THR B 1 78  ? 13.758  -11.057 11.861  1 15.093 ? 70   THR B C   1 
ATOM   4568 O  O   . THR B 1 78  ? 14.568  -11.222 10.932  1 18.903 ? 70   THR B O   1 
ATOM   4569 C  CB  . THR B 1 78  ? 13.488  -13.254 13.015  1 14.24  ? 70   THR B CB  1 
ATOM   4570 O  OG1 . THR B 1 78  ? 12.746  -14.471 13.05   1 13.757 ? 70   THR B OG1 1 
ATOM   4571 C  CG2 . THR B 1 78  ? 13.8    -12.817 14.452  1 13.145 ? 70   THR B CG2 1 
ATOM   4572 N  N   . PHE B 1 79  ? 13.618  -9.927  12.566  1 12.57  ? 71   PHE B N   1 
ATOM   4573 C  CA  . PHE B 1 79  ? 14.603  -8.867  12.54   1 10.827 ? 71   PHE B CA  1 
ATOM   4574 C  C   . PHE B 1 79  ? 15.536  -9.136  13.723  1 13.723 ? 71   PHE B C   1 
ATOM   4575 O  O   . PHE B 1 79  ? 15.096  -8.973  14.872  1 13.136 ? 71   PHE B O   1 
ATOM   4576 C  CB  . PHE B 1 79  ? 13.81   -7.561  12.774  1 13.385 ? 71   PHE B CB  1 
ATOM   4577 C  CG  . PHE B 1 79  ? 14.693  -6.303  12.701  1 15.81  ? 71   PHE B CG  1 
ATOM   4578 C  CD1 . PHE B 1 79  ? 15.989  -6.329  12.11   1 14.535 ? 71   PHE B CD1 1 
ATOM   4579 C  CD2 . PHE B 1 79  ? 14.219  -5.087  13.217  1 13.772 ? 71   PHE B CD2 1 
ATOM   4580 C  CE1 . PHE B 1 79  ? 16.783  -5.176  12.098  1 14.629 ? 71   PHE B CE1 1 
ATOM   4581 C  CE2 . PHE B 1 79  ? 14.996  -3.917  13.152  1 14.396 ? 71   PHE B CE2 1 
ATOM   4582 C  CZ  . PHE B 1 79  ? 16.282  -3.974  12.596  1 12.081 ? 71   PHE B CZ  1 
ATOM   4583 N  N   . TYR B 1 80  ? 16.752  -9.588  13.392  1 13.266 ? 72   TYR B N   1 
ATOM   4584 C  CA  . TYR B 1 80  ? 17.787  -9.778  14.394  1 12.677 ? 72   TYR B CA  1 
ATOM   4585 C  C   . TYR B 1 80  ? 18.708  -8.573  14.363  1 13.75  ? 72   TYR B C   1 
ATOM   4586 O  O   . TYR B 1 80  ? 19.144  -8.135  13.303  1 15.125 ? 72   TYR B O   1 
ATOM   4587 C  CB  . TYR B 1 80  ? 18.612  -11.018 14.123  1 11.551 ? 72   TYR B CB  1 
ATOM   4588 C  CG  . TYR B 1 80  ? 17.878  -12.351 14.225  1 13.129 ? 72   TYR B CG  1 
ATOM   4589 C  CD1 . TYR B 1 80  ? 17.785  -13.027 15.437  1 13.656 ? 72   TYR B CD1 1 
ATOM   4590 C  CD2 . TYR B 1 80  ? 17.383  -12.991 13.058  1 14.173 ? 72   TYR B CD2 1 
ATOM   4591 C  CE1 . TYR B 1 80  ? 17.143  -14.268 15.506  1 15.308 ? 72   TYR B CE1 1 
ATOM   4592 C  CE2 . TYR B 1 80  ? 16.719  -14.219 13.133  1 13.593 ? 72   TYR B CE2 1 
ATOM   4593 C  CZ  . TYR B 1 80  ? 16.597  -14.855 14.364  1 14.024 ? 72   TYR B CZ  1 
ATOM   4594 O  OH  . TYR B 1 80  ? 16      -16.12  14.471  1 15.602 ? 72   TYR B OH  1 
ATOM   4595 N  N   . ARG B 1 81  ? 19.033  -8.067  15.577  1 11.354 ? 73   ARG B N   1 
ATOM   4596 C  CA  . ARG B 1 81  ? 19.881  -6.904  15.612  1 12.655 ? 73   ARG B CA  1 
ATOM   4597 C  C   . ARG B 1 81  ? 20.939  -7.156  16.673  1 12.83  ? 73   ARG B C   1 
ATOM   4598 O  O   . ARG B 1 81  ? 20.606  -7.814  17.645  1 16.938 ? 73   ARG B O   1 
ATOM   4599 C  CB  . ARG B 1 81  ? 18.912  -5.76   15.968  1 14.875 ? 73   ARG B CB  1 
ATOM   4600 C  CG  . ARG B 1 81  ? 19.658  -4.438  15.973  1 21.385 ? 73   ARG B CG  1 
ATOM   4601 C  CD  . ARG B 1 81  ? 19.298  -3.622  14.788  1 17.355 ? 73   ARG B CD  1 
ATOM   4602 N  NE  . ARG B 1 81  ? 19.821  -2.303  15.167  1 16.892 ? 73   ARG B NE  1 
ATOM   4603 C  CZ  . ARG B 1 81  ? 20.93   -1.828  14.652  1 15.65  ? 73   ARG B CZ  1 
ATOM   4604 N  NH1 . ARG B 1 81  ? 21.353  -2.232  13.455  1 13.323 ? 73   ARG B NH1 1 
ATOM   4605 N  NH2 . ARG B 1 81  ? 21.577  -0.926  15.321  1 12.32  ? 73   ARG B NH2 1 
ATOM   4606 N  N   . ILE B 1 82  ? 22.184  -6.725  16.421  1 12.378 ? 74   ILE B N   1 
ATOM   4607 C  CA  . ILE B 1 82  ? 23.228  -7.034  17.382  1 13.961 ? 74   ILE B CA  1 
ATOM   4608 C  C   . ILE B 1 82  ? 23.797  -5.742  17.937  1 13.036 ? 74   ILE B C   1 
ATOM   4609 O  O   . ILE B 1 82  ? 24.081  -4.81   17.222  1 13.047 ? 74   ILE B O   1 
ATOM   4610 C  CB  . ILE B 1 82  ? 24.29   -7.98   16.765  1 13.318 ? 74   ILE B CB  1 
ATOM   4611 C  CG1 . ILE B 1 82  ? 25.224  -8.55   17.828  1 13.217 ? 74   ILE B CG1 1 
ATOM   4612 C  CG2 . ILE B 1 82  ? 25.102  -7.352  15.62   1 14.599 ? 74   ILE B CG2 1 
ATOM   4613 C  CD1 . ILE B 1 82  ? 25.968  -9.794  17.357  1 12.911 ? 74   ILE B CD1 1 
ATOM   4614 N  N   . MET B 1 83  ? 24.06   -5.743  19.256  1 12.461 ? 75   MET B N   1 
ATOM   4615 C  CA  . MET B 1 83  ? 24.562  -4.524  19.85   1 13.99  ? 75   MET B CA  1 
ATOM   4616 C  C   . MET B 1 83  ? 25.762  -4.812  20.76   1 12.778 ? 75   MET B C   1 
ATOM   4617 O  O   . MET B 1 83  ? 25.894  -5.944  21.249  1 11.961 ? 75   MET B O   1 
ATOM   4618 C  CB  . MET B 1 83  ? 23.485  -3.963  20.78   1 14.929 ? 75   MET B CB  1 
ATOM   4619 C  CG  . MET B 1 83  ? 22.232  -3.5    20.069  1 16.249 ? 75   MET B CG  1 
ATOM   4620 S  SD  . MET B 1 83  ? 20.797  -3.997  21.03   1 15.722 ? 75   MET B SD  1 
ATOM   4621 C  CE  . MET B 1 83  ? 20.838  -5.746  20.612  1 16.042 ? 75   MET B CE  1 
ATOM   4622 N  N   . PRO B 1 84  ? 26.66   -3.828  21.026  1 12.807 ? 76   PRO B N   1 
ATOM   4623 C  CA  . PRO B 1 84  ? 27.697  -4.035  22.009  1 11.088 ? 76   PRO B CA  1 
ATOM   4624 C  C   . PRO B 1 84  ? 27.207  -3.573  23.381  1 12.103 ? 76   PRO B C   1 
ATOM   4625 O  O   . PRO B 1 84  ? 26.634  -2.495  23.503  1 12.454 ? 76   PRO B O   1 
ATOM   4626 C  CB  . PRO B 1 84  ? 28.866  -3.159  21.485  1 12.069 ? 76   PRO B CB  1 
ATOM   4627 C  CG  . PRO B 1 84  ? 28.094  -1.94   20.931  1 13.687 ? 76   PRO B CG  1 
ATOM   4628 C  CD  . PRO B 1 84  ? 26.749  -2.501  20.371  1 14.624 ? 76   PRO B CD  1 
ATOM   4629 N  N   . ASP B 1 85  ? 27.397  -4.398  24.41   1 11.186 ? 77   ASP B N   1 
ATOM   4630 C  CA  . ASP B 1 85  ? 26.726  -4.03   25.657  1 10.676 ? 77   ASP B CA  1 
ATOM   4631 C  C   . ASP B 1 85  ? 27.545  -4.705  26.745  1 11.739 ? 77   ASP B C   1 
ATOM   4632 O  O   . ASP B 1 85  ? 27.214  -5.814  27.144  1 12.959 ? 77   ASP B O   1 
ATOM   4633 C  CB  . ASP B 1 85  ? 25.277  -4.527  25.705  1 9.438  ? 77   ASP B CB  1 
ATOM   4634 C  CG  . ASP B 1 85  ? 24.333  -3.893  26.713  1 11.766 ? 77   ASP B CG  1 
ATOM   4635 O  OD1 . ASP B 1 85  ? 24.723  -2.943  27.46   1 12.766 ? 77   ASP B OD1 1 
ATOM   4636 O  OD2 . ASP B 1 85  ? 23.177  -4.376  26.775  1 13.443 ? 77   ASP B OD2 1 
ATOM   4637 N  N   . TYR B 1 86  ? 28.74   -4.203  26.984  1 11.049 ? 78   TYR B N   1 
ATOM   4638 C  CA  . TYR B 1 86  ? 29.624  -4.808  27.975  1 13.174 ? 78   TYR B CA  1 
ATOM   4639 C  C   . TYR B 1 86  ? 28.847  -5.427  29.139  1 14.651 ? 78   TYR B C   1 
ATOM   4640 O  O   . TYR B 1 86  ? 28.071  -4.723  29.754  1 14.149 ? 78   TYR B O   1 
ATOM   4641 C  CB  . TYR B 1 86  ? 30.508  -3.704  28.532  1 16.161 ? 78   TYR B CB  1 
ATOM   4642 C  CG  . TYR B 1 86  ? 31.89   -3.585  27.94   1 14.157 ? 78   TYR B CG  1 
ATOM   4643 C  CD1 . TYR B 1 86  ? 32.73   -4.69   27.848  1 13.913 ? 78   TYR B CD1 1 
ATOM   4644 C  CD2 . TYR B 1 86  ? 32.299  -2.366  27.398  1 15.671 ? 78   TYR B CD2 1 
ATOM   4645 C  CE1 . TYR B 1 86  ? 34      -4.58   27.285  1 13.889 ? 78   TYR B CE1 1 
ATOM   4646 C  CE2 . TYR B 1 86  ? 33.57   -2.246  26.824  1 15.674 ? 78   TYR B CE2 1 
ATOM   4647 C  CZ  . TYR B 1 86  ? 34.416  -3.343  26.803  1 14.077 ? 78   TYR B CZ  1 
ATOM   4648 O  OH  . TYR B 1 86  ? 35.637  -3.111  26.285  1 15.434 ? 78   TYR B OH  1 
ATOM   4649 N  N   . ALA B 1 87  ? 29.01   -6.755  29.365  1 13.804 ? 79   ALA B N   1 
ATOM   4650 C  CA  . ALA B 1 87  ? 28.184  -7.49   30.319  1 12.079 ? 79   ALA B CA  1 
ATOM   4651 C  C   . ALA B 1 87  ? 28.721  -7.258  31.731  1 13.629 ? 79   ALA B C   1 
ATOM   4652 O  O   . ALA B 1 87  ? 27.975  -7.334  32.663  1 13.496 ? 79   ALA B O   1 
ATOM   4653 C  CB  . ALA B 1 87  ? 28.209  -8.971  29.971  1 13.583 ? 79   ALA B CB  1 
ATOM   4654 N  N   . GLN B 1 88  ? 30.034  -6.984  31.873  1 14.311 ? 80   GLN B N   1 
ATOM   4655 C  CA  . GLN B 1 88  ? 30.649  -6.592  33.155  1 16.623 ? 80   GLN B CA  1 
ATOM   4656 C  C   . GLN B 1 88  ? 31.308  -5.196  32.972  1 16.452 ? 80   GLN B C   1 
ATOM   4657 O  O   . GLN B 1 88  ? 31.679  -4.875  31.826  1 12.946 ? 80   GLN B O   1 
ATOM   4658 C  CB  . GLN B 1 88  ? 31.776  -7.572  33.58   1 12.345 ? 80   GLN B CB  1 
ATOM   4659 C  CG  . GLN B 1 88  ? 31.363  -9.022  33.873  1 12.763 ? 80   GLN B CG  1 
ATOM   4660 C  CD  . GLN B 1 88  ? 30.357  -9.14   35.006  1 18.091 ? 80   GLN B CD  1 
ATOM   4661 O  OE1 . GLN B 1 88  ? 29.333  -9.838  34.89   1 14.89  ? 80   GLN B OE1 1 
ATOM   4662 N  NE2 . GLN B 1 88  ? 30.667  -8.51   36.141  1 14.784 ? 80   GLN B NE2 1 
ATOM   4663 N  N   . PRO B 1 89  ? 31.522  -4.383  34.046  1 14.054 ? 81   PRO B N   1 
ATOM   4664 C  CA  . PRO B 1 89  ? 32.245  -3.117  33.921  1 15.455 ? 81   PRO B CA  1 
ATOM   4665 C  C   . PRO B 1 89  ? 33.675  -3.4    33.449  1 16.321 ? 81   PRO B C   1 
ATOM   4666 O  O   . PRO B 1 89  ? 34.374  -4.195  34.088  1 22.758 ? 81   PRO B O   1 
ATOM   4667 C  CB  . PRO B 1 89  ? 32.261  -2.492  35.354  1 17.86  ? 81   PRO B CB  1 
ATOM   4668 C  CG  . PRO B 1 89  ? 31.903  -3.664  36.259  1 16.829 ? 81   PRO B CG  1 
ATOM   4669 C  CD  . PRO B 1 89  ? 31.202  -4.723  35.456  1 16.685 ? 81   PRO B CD  1 
ATOM   4670 N  N   . PRO B 1 90  ? 34.111  -2.893  32.251  1 18.717 ? 82   PRO B N   1 
ATOM   4671 C  CA  . PRO B 1 90  ? 35.355  -3.298  31.594  1 14.403 ? 82   PRO B CA  1 
ATOM   4672 C  C   . PRO B 1 90  ? 36.634  -2.735  32.262  1 15.402 ? 82   PRO B C   1 
ATOM   4673 O  O   . PRO B 1 90  ? 37.405  -1.999  31.642  1 17.159 ? 82   PRO B O   1 
ATOM   4674 C  CB  . PRO B 1 90  ? 35.08   -2.882  30.109  1 12.081 ? 82   PRO B CB  1 
ATOM   4675 C  CG  . PRO B 1 90  ? 34.289  -1.607  30.32   1 13.163 ? 82   PRO B CG  1 
ATOM   4676 C  CD  . PRO B 1 90  ? 33.307  -1.987  31.396  1 16.373 ? 82   PRO B CD  1 
ATOM   4677 N  N   . THR B 1 91  ? 36.818  -2.989  33.568  1 13.477 ? 83   THR B N   1 
ATOM   4678 C  CA  . THR B 1 91  ? 37.805  -2.199  34.321  1 13.349 ? 83   THR B CA  1 
ATOM   4679 C  C   . THR B 1 91  ? 39.202  -2.824  34.294  1 15.278 ? 83   THR B C   1 
ATOM   4680 O  O   . THR B 1 91  ? 40.097  -2.223  34.844  1 17.832 ? 83   THR B O   1 
ATOM   4681 C  CB  . THR B 1 91  ? 37.419  -2.006  35.806  1 12.33  ? 83   THR B CB  1 
ATOM   4682 O  OG1 . THR B 1 91  ? 37.006  -3.305  36.186  1 12.011 ? 83   THR B OG1 1 
ATOM   4683 C  CG2 . THR B 1 91  ? 36.24   -1.097  36.018  1 15.744 ? 83   THR B CG2 1 
ATOM   4684 N  N   . TYR B 1 92  ? 39.433  -3.932  33.591  1 13.937 ? 84   TYR B N   1 
ATOM   4685 C  CA  . TYR B 1 92  ? 40.705  -4.667  33.604  1 13.552 ? 84   TYR B CA  1 
ATOM   4686 C  C   . TYR B 1 92  ? 41.91   -3.758  33.34   1 15.534 ? 84   TYR B C   1 
ATOM   4687 O  O   . TYR B 1 92  ? 42.911  -3.772  34.104  1 13.327 ? 84   TYR B O   1 
ATOM   4688 C  CB  . TYR B 1 92  ? 40.736  -5.98   32.809  1 15.462 ? 84   TYR B CB  1 
ATOM   4689 C  CG  . TYR B 1 92  ? 42.125  -6.597  32.81   1 18.973 ? 84   TYR B CG  1 
ATOM   4690 C  CD1 . TYR B 1 92  ? 42.609  -7.155  34.011  1 21.389 ? 84   TYR B CD1 1 
ATOM   4691 C  CD2 . TYR B 1 92  ? 43.02   -6.458  31.734  1 17.756 ? 84   TYR B CD2 1 
ATOM   4692 C  CE1 . TYR B 1 92  ? 43.888  -7.678  34.084  1 24.725 ? 84   TYR B CE1 1 
ATOM   4693 C  CE2 . TYR B 1 92  ? 44.349  -6.872  31.869  1 21.413 ? 84   TYR B CE2 1 
ATOM   4694 C  CZ  . TYR B 1 92  ? 44.779  -7.486  33.045  1 21.426 ? 84   TYR B CZ  1 
ATOM   4695 O  OH  . TYR B 1 92  ? 46.052  -7.978  33.232  1 22.939 ? 84   TYR B OH  1 
ATOM   4696 N  N   . TYR B 1 93  ? 41.914  -3.115  32.164  1 16.861 ? 85   TYR B N   1 
ATOM   4697 C  CA  . TYR B 1 93  ? 43.068  -2.345  31.733  1 18.554 ? 85   TYR B CA  1 
ATOM   4698 C  C   . TYR B 1 93  ? 42.791  -0.849  31.873  1 18.696 ? 85   TYR B C   1 
ATOM   4699 O  O   . TYR B 1 93  ? 41.825  -0.309  31.296  1 16.942 ? 85   TYR B O   1 
ATOM   4700 C  CB  . TYR B 1 93  ? 43.372  -2.679  30.262  1 17.754 ? 85   TYR B CB  1 
ATOM   4701 C  CG  . TYR B 1 93  ? 44.639  -2.055  29.701  1 21.676 ? 85   TYR B CG  1 
ATOM   4702 C  CD1 . TYR B 1 93  ? 45.889  -2.539  30.088  1 22.447 ? 85   TYR B CD1 1 
ATOM   4703 C  CD2 . TYR B 1 93  ? 44.587  -1.01   28.792  1 24.303 ? 85   TYR B CD2 1 
ATOM   4704 C  CE1 . TYR B 1 93  ? 47.053  -1.969  29.606  1 26.501 ? 85   TYR B CE1 1 
ATOM   4705 C  CE2 . TYR B 1 93  ? 45.745  -0.452  28.271  1 27.029 ? 85   TYR B CE2 1 
ATOM   4706 C  CZ  . TYR B 1 93  ? 46.981  -0.932  28.683  1 26.26  ? 85   TYR B CZ  1 
ATOM   4707 O  OH  . TYR B 1 93  ? 48.162  -0.399  28.204  1 26.229 ? 85   TYR B OH  1 
ATOM   4708 N  N   . LYS B 1 94  ? 43.712  -0.149  32.58   1 19.731 ? 86   LYS B N   1 
ATOM   4709 C  CA  . LYS B 1 94  ? 43.599  1.277   32.906  1 19.76  ? 86   LYS B CA  1 
ATOM   4710 C  C   . LYS B 1 94  ? 42.17   1.663   33.351  1 19.414 ? 86   LYS B C   1 
ATOM   4711 O  O   . LYS B 1 94  ? 41.625  2.666   32.877  1 17.252 ? 86   LYS B O   1 
ATOM   4712 C  CB  . LYS B 1 94  ? 44.098  2.055   31.664  1 22.495 ? 86   LYS B CB  1 
ATOM   4713 C  CG  . LYS B 1 94  ? 45.592  1.916   31.36   1 23.006 ? 86   LYS B CG  1 
ATOM   4714 C  CD  . LYS B 1 94  ? 46.028  2.635   30.08   1 24.049 ? 86   LYS B CD  1 
ATOM   4715 C  CE  . LYS B 1 94  ? 47.496  2.605   29.787  1 24.575 ? 86   LYS B CE  1 
ATOM   4716 N  NZ  . LYS B 1 94  ? 47.67   3.399   28.54   1 22.558 ? 86   LYS B NZ  1 
ATOM   4717 N  N   . GLY B 1 95  ? 41.528  0.783   34.146  1 18.009 ? 87   GLY B N   1 
ATOM   4718 C  CA  . GLY B 1 95  ? 40.205  1.001   34.716  1 18.293 ? 87   GLY B CA  1 
ATOM   4719 C  C   . GLY B 1 95  ? 39.14   1.143   33.628  1 22.038 ? 87   GLY B C   1 
ATOM   4720 O  O   . GLY B 1 95  ? 38.073  1.715   33.887  1 20.309 ? 87   GLY B O   1 
ATOM   4721 N  N   . GLY B 1 96  ? 39.5    0.675   32.413  1 18.438 ? 88   GLY B N   1 
ATOM   4722 C  CA  . GLY B 1 96  ? 38.587  0.734   31.27   1 26.525 ? 88   GLY B CA  1 
ATOM   4723 C  C   . GLY B 1 96  ? 38.48   2.116   30.627  1 22.591 ? 88   GLY B C   1 
ATOM   4724 O  O   . GLY B 1 96  ? 37.564  2.368   29.829  1 17.383 ? 88   GLY B O   1 
ATOM   4725 N  N   . GLU B 1 97  ? 39.468  2.989   30.894  1 19.361 ? 89   GLU B N   1 
ATOM   4726 C  CA  . GLU B 1 97  ? 39.306  4.37    30.456  1 21.489 ? 89   GLU B CA  1 
ATOM   4727 C  C   . GLU B 1 97  ? 39.451  4.497   28.935  1 18.097 ? 89   GLU B C   1 
ATOM   4728 O  O   . GLU B 1 97  ? 38.919  5.451   28.355  1 18.674 ? 89   GLU B O   1 
ATOM   4729 C  CB  . GLU B 1 97  ? 40.102  5.4     31.23   1 30.549 ? 89   GLU B CB  1 
ATOM   4730 C  CG  . GLU B 1 97  ? 39.634  5.417   32.682  1 46.991 ? 89   GLU B CG  1 
ATOM   4731 C  CD  . GLU B 1 97  ? 39.897  6.722   33.408  1 57.703 ? 89   GLU B CD  1 
ATOM   4732 O  OE1 . GLU B 1 97  ? 41.085  7.08    33.525  1 63.187 ? 89   GLU B OE1 1 
ATOM   4733 O  OE2 . GLU B 1 97  ? 38.915  7.393   33.817  1 69.55  ? 89   GLU B OE2 1 
ATOM   4734 N  N   . LEU B 1 98  ? 39.992  3.454   28.312  1 15.556 ? 90   LEU B N   1 
ATOM   4735 C  CA  . LEU B 1 98  ? 40.228  3.48    26.879  1 17.018 ? 90   LEU B CA  1 
ATOM   4736 C  C   . LEU B 1 98  ? 39.323  2.489   26.128  1 19.334 ? 90   LEU B C   1 
ATOM   4737 O  O   . LEU B 1 98  ? 39.64   2.123   24.986  1 18.931 ? 90   LEU B O   1 
ATOM   4738 C  CB  . LEU B 1 98  ? 41.699  3.203   26.602  1 17.248 ? 90   LEU B CB  1 
ATOM   4739 C  CG  . LEU B 1 98  ? 42.661  4.319   27.036  1 23.8   ? 90   LEU B CG  1 
ATOM   4740 C  CD1 . LEU B 1 98  ? 44.105  3.841   26.9    1 23.486 ? 90   LEU B CD1 1 
ATOM   4741 C  CD2 . LEU B 1 98  ? 42.394  5.713   26.443  1 21.665 ? 90   LEU B CD2 1 
ATOM   4742 N  N   . ASN B 1 99  ? 38.194  2.067   26.732  1 20.532 ? 91   ASN B N   1 
ATOM   4743 C  CA  . ASN B 1 99  ? 37.314  1.104   26.047  1 15.565 ? 91   ASN B CA  1 
ATOM   4744 C  C   . ASN B 1 99  ? 36.742  1.831   24.856  1 13.97  ? 91   ASN B C   1 
ATOM   4745 O  O   . ASN B 1 99  ? 36.511  3.075   24.964  1 14.953 ? 91   ASN B O   1 
ATOM   4746 C  CB  . ASN B 1 99  ? 36.328  0.49    27.029  1 14.425 ? 91   ASN B CB  1 
ATOM   4747 C  CG  . ASN B 1 99  ? 35.135  1.41    27.3    1 16.887 ? 91   ASN B CG  1 
ATOM   4748 O  OD1 . ASN B 1 99  ? 34.271  1.55    26.424  1 14.291 ? 91   ASN B OD1 1 
ATOM   4749 N  ND2 . ASN B 1 99  ? 35.05   2.047   28.466  1 14.072 ? 91   ASN B ND2 1 
ATOM   4750 N  N   . ALA B 1 100 ? 36.631  1.15    23.695  1 14.125 ? 92   ALA B N   1 
ATOM   4751 C  CA  . ALA B 1 100 ? 36.09   1.76    22.486  1 13.024 ? 92   ALA B CA  1 
ATOM   4752 C  C   . ALA B 1 100 ? 34.585  1.439   22.353  1 12.735 ? 92   ALA B C   1 
ATOM   4753 O  O   . ALA B 1 100 ? 34.107  0.429   22.879  1 16.624 ? 92   ALA B O   1 
ATOM   4754 C  CB  . ALA B 1 100 ? 36.848  1.278   21.23   1 11.328 ? 92   ALA B CB  1 
ATOM   4755 N  N   . PRO B 1 101 ? 33.74   2.256   21.663  1 13.46  ? 93   PRO B N   1 
ATOM   4756 C  CA  . PRO B 1 101 ? 32.322  1.92    21.456  1 12.773 ? 93   PRO B CA  1 
ATOM   4757 C  C   . PRO B 1 101 ? 32.046  0.574   20.773  1 14.087 ? 93   PRO B C   1 
ATOM   4758 O  O   . PRO B 1 101 ? 30.963  0.013   20.928  1 15.778 ? 93   PRO B O   1 
ATOM   4759 C  CB  . PRO B 1 101 ? 31.759  3.108   20.692  1 12.77  ? 93   PRO B CB  1 
ATOM   4760 C  CG  . PRO B 1 101 ? 33.029  3.718   20.062  1 13.155 ? 93   PRO B CG  1 
ATOM   4761 C  CD  . PRO B 1 101 ? 34.091  3.571   21.06   1 13.707 ? 93   PRO B CD  1 
ATOM   4762 N  N   . ILE B 1 102 ? 33.027  0.07    20.018  1 12.869 ? 94   ILE B N   1 
ATOM   4763 C  CA  . ILE B 1 102 ? 32.957  -1.183  19.276  1 12.929 ? 94   ILE B CA  1 
ATOM   4764 C  C   . ILE B 1 102 ? 33.458  -2.341  20.128  1 12.318 ? 94   ILE B C   1 
ATOM   4765 O  O   . ILE B 1 102 ? 33.572  -3.436  19.606  1 11.644 ? 94   ILE B O   1 
ATOM   4766 C  CB  . ILE B 1 102 ? 33.718  -1.074  17.923  1 11.773 ? 94   ILE B CB  1 
ATOM   4767 C  CG1 . ILE B 1 102 ? 35.258  -0.835  18.135  1 11.762 ? 94   ILE B CG1 1 
ATOM   4768 C  CG2 . ILE B 1 102 ? 33.087  0.017   17.043  1 11.039 ? 94   ILE B CG2 1 
ATOM   4769 C  CD1 . ILE B 1 102 ? 36.099  -0.955  16.859  1 14.393 ? 94   ILE B CD1 1 
ATOM   4770 N  N   . ASP B 1 103 ? 33.735  -2.126  21.449  1 11.013 ? 95   ASP B N   1 
ATOM   4771 C  CA  . ASP B 1 103 ? 34.318  -3.217  22.202  1 11.741 ? 95   ASP B CA  1 
ATOM   4772 C  C   . ASP B 1 103 ? 33.292  -4.182  22.809  1 13.065 ? 95   ASP B C   1 
ATOM   4773 O  O   . ASP B 1 103 ? 33.612  -5.38   22.963  1 14.099 ? 95   ASP B O   1 
ATOM   4774 C  CB  . ASP B 1 103 ? 35.224  -2.811  23.365  1 14.395 ? 95   ASP B CB  1 
ATOM   4775 C  CG  . ASP B 1 103 ? 36.695  -2.597  22.998  1 13.463 ? 95   ASP B CG  1 
ATOM   4776 O  OD1 . ASP B 1 103 ? 37.369  -3.525  22.58   1 12.207 ? 95   ASP B OD1 1 
ATOM   4777 O  OD2 . ASP B 1 103 ? 37.196  -1.556  23.259  1 15.491 ? 95   ASP B OD2 1 
ATOM   4778 N  N   . GLY B 1 104 ? 32.117  -3.683  23.253  1 15.111 ? 96   GLY B N   1 
ATOM   4779 C  CA  . GLY B 1 104 ? 31.39   -4.422  24.291  1 15.553 ? 96   GLY B CA  1 
ATOM   4780 C  C   . GLY B 1 104 ? 30.789  -5.753  23.8    1 13.339 ? 96   GLY B C   1 
ATOM   4781 O  O   . GLY B 1 104 ? 30.605  -5.972  22.582  1 10.104 ? 96   GLY B O   1 
ATOM   4782 N  N   . ASP B 1 105 ? 30.631  -6.698  24.741  1 11.063 ? 97   ASP B N   1 
ATOM   4783 C  CA  . ASP B 1 105 ? 30.118  -8.055  24.476  1 10.627 ? 97   ASP B CA  1 
ATOM   4784 C  C   . ASP B 1 105 ? 28.844  -7.986  23.636  1 12.929 ? 97   ASP B C   1 
ATOM   4785 O  O   . ASP B 1 105 ? 27.941  -7.231  23.988  1 11.78  ? 97   ASP B O   1 
ATOM   4786 C  CB  . ASP B 1 105 ? 29.643  -8.666  25.785  1 11.815 ? 97   ASP B CB  1 
ATOM   4787 C  CG  . ASP B 1 105 ? 30.798  -8.801  26.739  1 10.452 ? 97   ASP B CG  1 
ATOM   4788 O  OD1 . ASP B 1 105 ? 31.718  -9.59   26.398  1 11.544 ? 97   ASP B OD1 1 
ATOM   4789 O  OD2 . ASP B 1 105 ? 30.8    -8.125  27.759  1 14.866 ? 97   ASP B OD2 1 
ATOM   4790 N  N   . GLY B 1 106 ? 28.815  -8.789  22.559  1 11.64  ? 98   GLY B N   1 
ATOM   4791 C  CA  . GLY B 1 106 ? 27.687  -8.825  21.632  1 12.2   ? 98   GLY B CA  1 
ATOM   4792 C  C   . GLY B 1 106 ? 26.408  -9.392  22.283  1 13.033 ? 98   GLY B C   1 
ATOM   4793 O  O   . GLY B 1 106 ? 26.422  -10.396 23.011  1 15.298 ? 98   GLY B O   1 
ATOM   4794 N  N   . THR B 1 107 ? 25.305  -8.668  22.128  1 13.669 ? 99   THR B N   1 
ATOM   4795 C  CA  . THR B 1 107 ? 24.017  -9.206  22.501  1 13.224 ? 99   THR B CA  1 
ATOM   4796 C  C   . THR B 1 107 ? 23.095  -9.086  21.29   1 12.984 ? 99   THR B C   1 
ATOM   4797 O  O   . THR B 1 107 ? 23.143  -8.051  20.634  1 14.037 ? 99   THR B O   1 
ATOM   4798 C  CB  . THR B 1 107 ? 23.49   -8.47   23.735  1 12.669 ? 99   THR B CB  1 
ATOM   4799 O  OG1 . THR B 1 107 ? 22.174  -8.981  23.936  1 11.853 ? 99   THR B OG1 1 
ATOM   4800 C  CG2 . THR B 1 107 ? 23.432  -6.942  23.622  1 13.022 ? 99   THR B CG2 1 
ATOM   4801 N  N   . VAL B 1 108 ? 22.276  -10.114 21.063  1 14.476 ? 100  VAL B N   1 
ATOM   4802 C  CA  . VAL B 1 108 ? 21.4    -10.197 19.871  1 14.236 ? 100  VAL B CA  1 
ATOM   4803 C  C   . VAL B 1 108 ? 19.974  -10.002 20.369  1 12.937 ? 100  VAL B C   1 
ATOM   4804 O  O   . VAL B 1 108 ? 19.565  -10.675 21.317  1 13.128 ? 100  VAL B O   1 
ATOM   4805 C  CB  . VAL B 1 108 ? 21.504  -11.545 19.116  1 16.356 ? 100  VAL B CB  1 
ATOM   4806 C  CG1 . VAL B 1 108 ? 20.42   -11.723 18      1 16.435 ? 100  VAL B CG1 1 
ATOM   4807 C  CG2 . VAL B 1 108 ? 22.909  -11.755 18.582  1 13.7   ? 100  VAL B CG2 1 
ATOM   4808 N  N   . ALA B 1 109 ? 19.265  -9.013  19.794  1 11.568 ? 101  ALA B N   1 
ATOM   4809 C  CA  . ALA B 1 109 ? 17.846  -8.876  20.064  1 10.935 ? 101  ALA B CA  1 
ATOM   4810 C  C   . ALA B 1 109 ? 17.123  -9.436  18.846  1 16.49  ? 101  ALA B C   1 
ATOM   4811 O  O   . ALA B 1 109 ? 17.502  -9.064  17.742  1 15.221 ? 101  ALA B O   1 
ATOM   4812 C  CB  . ALA B 1 109 ? 17.549  -7.396  20.23   1 12.327 ? 101  ALA B CB  1 
ATOM   4813 N  N   . ALA B 1 110 ? 16.161  -10.364 19.038  1 17.766 ? 102  ALA B N   1 
ATOM   4814 C  CA  . ALA B 1 110 ? 15.398  -10.856 17.914  1 14.203 ? 102  ALA B CA  1 
ATOM   4815 C  C   . ALA B 1 110 ? 13.946  -10.352 18.022  1 15.265 ? 102  ALA B C   1 
ATOM   4816 O  O   . ALA B 1 110 ? 13.358  -10.363 19.109  1 15.161 ? 102  ALA B O   1 
ATOM   4817 C  CB  . ALA B 1 110 ? 15.435  -12.349 17.985  1 14.935 ? 102  ALA B CB  1 
ATOM   4818 N  N   . PHE B 1 111 ? 13.372  -9.943  16.875  1 13.101 ? 103  PHE B N   1 
ATOM   4819 C  CA  . PHE B 1 111 ? 11.97   -9.496  16.805  1 14.165 ? 103  PHE B CA  1 
ATOM   4820 C  C   . PHE B 1 111 ? 11.228  -10.286 15.751  1 13.347 ? 103  PHE B C   1 
ATOM   4821 O  O   . PHE B 1 111 ? 11.442  -10.048 14.556  1 12.815 ? 103  PHE B O   1 
ATOM   4822 C  CB  . PHE B 1 111 ? 11.764  -8.005  16.444  1 14.176 ? 103  PHE B CB  1 
ATOM   4823 C  CG  . PHE B 1 111 ? 12.422  -7.035  17.426  1 15.381 ? 103  PHE B CG  1 
ATOM   4824 C  CD1 . PHE B 1 111 ? 13.786  -6.677  17.28   1 18.685 ? 103  PHE B CD1 1 
ATOM   4825 C  CD2 . PHE B 1 111 ? 11.684  -6.466  18.458  1 16.539 ? 103  PHE B CD2 1 
ATOM   4826 C  CE1 . PHE B 1 111 ? 14.399  -5.792  18.203  1 20.116 ? 103  PHE B CE1 1 
ATOM   4827 C  CE2 . PHE B 1 111 ? 12.258  -5.527  19.328  1 16.148 ? 103  PHE B CE2 1 
ATOM   4828 C  CZ  . PHE B 1 111 ? 13.614  -5.217  19.212  1 18.889 ? 103  PHE B CZ  1 
ATOM   4829 N  N   . ARG B 1 112 ? 10.403  -11.232 16.191  1 13.729 ? 104  ARG B N   1 
ATOM   4830 C  CA  . ARG B 1 112 ? 9.893   -12.211 15.237  1 15.602 ? 104  ARG B CA  1 
ATOM   4831 C  C   . ARG B 1 112 ? 8.407   -11.882 14.944  1 15.728 ? 104  ARG B C   1 
ATOM   4832 O  O   . ARG B 1 112 ? 7.615   -11.685 15.857  1 15     ? 104  ARG B O   1 
ATOM   4833 C  CB  . ARG B 1 112 ? 10.108  -13.612 15.832  1 13.108 ? 104  ARG B CB  1 
ATOM   4834 C  CG  . ARG B 1 112 ? 9.525   -14.573 14.784  1 16.194 ? 104  ARG B CG  1 
ATOM   4835 C  CD  . ARG B 1 112 ? 9.861   -16.029 15.091  1 15.221 ? 104  ARG B CD  1 
ATOM   4836 N  NE  . ARG B 1 112 ? 11.293  -16.227 14.901  1 15.61  ? 104  ARG B NE  1 
ATOM   4837 C  CZ  . ARG B 1 112 ? 12.028  -17.289 15.149  1 13.685 ? 104  ARG B CZ  1 
ATOM   4838 N  NH1 . ARG B 1 112 ? 11.491  -18.405 15.648  1 13.814 ? 104  ARG B NH1 1 
ATOM   4839 N  NH2 . ARG B 1 112 ? 13.328  -17.22  14.913  1 13.891 ? 104  ARG B NH2 1 
ATOM   4840 N  N   . PHE B 1 113 ? 8.135   -11.758 13.627  1 18.165 ? 105  PHE B N   1 
ATOM   4841 C  CA  . PHE B 1 113 ? 6.898   -11.299 13.016  1 18.027 ? 105  PHE B CA  1 
ATOM   4842 C  C   . PHE B 1 113 ? 6.267   -12.515 12.338  1 18.17  ? 105  PHE B C   1 
ATOM   4843 O  O   . PHE B 1 113 ? 6.848   -13.171 11.441  1 18.682 ? 105  PHE B O   1 
ATOM   4844 C  CB  . PHE B 1 113 ? 7.203   -10.186 12      1 16.939 ? 105  PHE B CB  1 
ATOM   4845 C  CG  . PHE B 1 113 ? 7.729   -8.853  12.513  1 17.377 ? 105  PHE B CG  1 
ATOM   4846 C  CD1 . PHE B 1 113 ? 9.082   -8.719  12.865  1 16.442 ? 105  PHE B CD1 1 
ATOM   4847 C  CD2 . PHE B 1 113 ? 6.888   -7.733  12.624  1 15.941 ? 105  PHE B CD2 1 
ATOM   4848 C  CE1 . PHE B 1 113 ? 9.594   -7.505  13.305  1 16.653 ? 105  PHE B CE1 1 
ATOM   4849 C  CE2 . PHE B 1 113 ? 7.401   -6.494  13.058  1 15.551 ? 105  PHE B CE2 1 
ATOM   4850 C  CZ  . PHE B 1 113 ? 8.754   -6.391  13.406  1 17.602 ? 105  PHE B CZ  1 
ATOM   4851 N  N   . LYS B 1 114 ? 5.064   -12.834 12.824  1 19.85  ? 106  LYS B N   1 
ATOM   4852 C  CA  . LYS B 1 114 ? 4.336   -14.008 12.361  1 19.564 ? 106  LYS B CA  1 
ATOM   4853 C  C   . LYS B 1 114 ? 2.863   -13.715 12.546  1 17.694 ? 106  LYS B C   1 
ATOM   4854 O  O   . LYS B 1 114 ? 2.384   -13.495 13.679  1 17.366 ? 106  LYS B O   1 
ATOM   4855 C  CB  . LYS B 1 114 ? 4.864   -15.343 12.905  1 23.877 ? 106  LYS B CB  1 
ATOM   4856 C  CG  . LYS B 1 114 ? 4.294   -16.631 12.382  1 27.697 ? 106  LYS B CG  1 
ATOM   4857 C  CD  . LYS B 1 114 ? 5.15    -17.781 12.916  1 28.628 ? 106  LYS B CD  1 
ATOM   4858 C  CE  . LYS B 1 114 ? 4.78    -19.126 12.348  1 39.038 ? 106  LYS B CE  1 
ATOM   4859 N  NZ  . LYS B 1 114 ? 3.349   -19.43  12.561  1 33.767 ? 106  LYS B NZ  1 
ATOM   4860 N  N   . ASP B 1 115 ? 2.153   -13.666 11.406  1 21.913 ? 107  ASP B N   1 
ATOM   4861 C  CA  . ASP B 1 115 ? 0.709   -13.392 11.43   1 23.344 ? 107  ASP B CA  1 
ATOM   4862 C  C   . ASP B 1 115 ? 0.392   -12.112 12.225  1 21.742 ? 107  ASP B C   1 
ATOM   4863 O  O   . ASP B 1 115 ? -0.622  -12.032 12.894  1 22.608 ? 107  ASP B O   1 
ATOM   4864 C  CB  . ASP B 1 115 ? -0.074  -14.579 12.008  1 33.643 ? 107  ASP B CB  1 
ATOM   4865 C  CG  . ASP B 1 115 ? 0.059   -15.927 11.303  1 42.421 ? 107  ASP B CG  1 
ATOM   4866 O  OD1 . ASP B 1 115 ? 0.052   -15.945 10.045  1 45.505 ? 107  ASP B OD1 1 
ATOM   4867 O  OD2 . ASP B 1 115 ? 0.097   -16.961 12.01   1 49.184 ? 107  ASP B OD2 1 
ATOM   4868 N  N   . GLY B 1 116 ? 1.251   -11.087 12.152  1 16.111 ? 108  GLY B N   1 
ATOM   4869 C  CA  . GLY B 1 116 ? 0.903   -9.793  12.704  1 18.235 ? 108  GLY B CA  1 
ATOM   4870 C  C   . GLY B 1 116 ? 1.241   -9.753  14.22   1 19.581 ? 108  GLY B C   1 
ATOM   4871 O  O   . GLY B 1 116 ? 1.06    -8.708  14.844  1 20.007 ? 108  GLY B O   1 
ATOM   4872 N  N   . LYS B 1 117 ? 1.713   -10.877 14.784  1 15.253 ? 109  LYS B N   1 
ATOM   4873 C  CA  . LYS B 1 117 ? 2.154   -10.842 16.192  1 14.464 ? 109  LYS B CA  1 
ATOM   4874 C  C   . LYS B 1 117 ? 3.66    -10.633 16.157  1 14.417 ? 109  LYS B C   1 
ATOM   4875 O  O   . LYS B 1 117 ? 4.287   -11.237 15.288  1 15.364 ? 109  LYS B O   1 
ATOM   4876 C  CB  . LYS B 1 117 ? 1.899   -12.162 16.943  1 15.661 ? 109  LYS B CB  1 
ATOM   4877 C  CG  . LYS B 1 117 ? 2.253   -12.108 18.506  1 18.585 ? 109  LYS B CG  1 
ATOM   4878 C  CD  . LYS B 1 117 ? 1.935   -13.136 19.616  1 19.707 ? 109  LYS B CD  1 
ATOM   4879 C  CE  . LYS B 1 117 ? 2.107   -14.643 19.327  1 18.993 ? 109  LYS B CE  1 
ATOM   4880 N  NZ  . LYS B 1 117 ? 3.472   -15.086 19.047  1 19.327 ? 109  LYS B NZ  1 
ATOM   4881 N  N   . VAL B 1 118 ? 4.218   -9.993  17.216  1 14.851 ? 110  VAL B N   1 
ATOM   4882 C  CA  . VAL B 1 118 ? 5.647   -9.756  17.35   1 13.008 ? 110  VAL B CA  1 
ATOM   4883 C  C   . VAL B 1 118 ? 6.117   -10.274 18.708  1 13.902 ? 110  VAL B C   1 
ATOM   4884 O  O   . VAL B 1 118 ? 5.526   -9.843  19.707  1 10.867 ? 110  VAL B O   1 
ATOM   4885 C  CB  . VAL B 1 118 ? 6.039   -8.276  17.192  1 12.129 ? 110  VAL B CB  1 
ATOM   4886 C  CG1 . VAL B 1 118 ? 7.545   -8.156  17.195  1 14.442 ? 110  VAL B CG1 1 
ATOM   4887 C  CG2 . VAL B 1 118 ? 5.687   -7.798  15.774  1 15.946 ? 110  VAL B CG2 1 
ATOM   4888 N  N   . ASP B 1 119 ? 7.189   -11.094 18.692  1 14.382 ? 111  ASP B N   1 
ATOM   4889 C  CA  . ASP B 1 119 ? 7.793   -11.488 19.948  1 14.54  ? 111  ASP B CA  1 
ATOM   4890 C  C   . ASP B 1 119 ? 9.256   -11.014 19.932  1 15.78  ? 111  ASP B C   1 
ATOM   4891 O  O   . ASP B 1 119 ? 9.849   -10.766 18.861  1 12.554 ? 111  ASP B O   1 
ATOM   4892 C  CB  . ASP B 1 119 ? 7.786   -12.996 20.134  1 13.649 ? 111  ASP B CB  1 
ATOM   4893 C  CG  . ASP B 1 119 ? 6.432   -13.704 20.273  1 13.128 ? 111  ASP B CG  1 
ATOM   4894 O  OD1 . ASP B 1 119 ? 5.411   -13.085 20.624  1 15.058 ? 111  ASP B OD1 1 
ATOM   4895 O  OD2 . ASP B 1 119 ? 6.416   -14.928 20.024  1 18.346 ? 111  ASP B OD2 1 
ATOM   4896 N  N   . TYR B 1 120 ? 9.82    -10.912 21.139  1 11.008 ? 112  TYR B N   1 
ATOM   4897 C  CA  . TYR B 1 120 ? 11.164  -10.397 21.274  1 12.784 ? 112  TYR B CA  1 
ATOM   4898 C  C   . TYR B 1 120 ? 11.903  -11.344 22.186  1 13.37  ? 112  TYR B C   1 
ATOM   4899 O  O   . TYR B 1 120 ? 11.342  -11.758 23.219  1 15.184 ? 112  TYR B O   1 
ATOM   4900 C  CB  . TYR B 1 120 ? 11.073  -9.037  21.963  1 13.151 ? 112  TYR B CB  1 
ATOM   4901 C  CG  . TYR B 1 120 ? 12.264  -8.469  22.707  1 16.434 ? 112  TYR B CG  1 
ATOM   4902 C  CD1 . TYR B 1 120 ? 13.373  -7.875  22.073  1 19.902 ? 112  TYR B CD1 1 
ATOM   4903 C  CD2 . TYR B 1 120 ? 12.28   -8.607  24.093  1 19.045 ? 112  TYR B CD2 1 
ATOM   4904 C  CE1 . TYR B 1 120 ? 14.418  -7.353  22.842  1 20.942 ? 112  TYR B CE1 1 
ATOM   4905 C  CE2 . TYR B 1 120 ? 13.342  -8.144  24.833  1 18.083 ? 112  TYR B CE2 1 
ATOM   4906 C  CZ  . TYR B 1 120 ? 14.404  -7.511  24.226  1 19.769 ? 112  TYR B CZ  1 
ATOM   4907 O  OH  . TYR B 1 120 ? 15.344  -7.187  25.206  1 18.376 ? 112  TYR B OH  1 
ATOM   4908 N  N   . ARG B 1 121 ? 13.192  -11.502 21.873  1 13.528 ? 113  ARG B N   1 
ATOM   4909 C  CA  . ARG B 1 121 ? 14.154  -12.186 22.708  1 13.78  ? 113  ARG B CA  1 
ATOM   4910 C  C   . ARG B 1 121 ? 15.494  -11.47  22.569  1 15.139 ? 113  ARG B C   1 
ATOM   4911 O  O   . ARG B 1 121 ? 15.926  -11.109 21.461  1 14.07  ? 113  ARG B O   1 
ATOM   4912 C  CB  . ARG B 1 121 ? 14.204  -13.678 22.293  1 16.305 ? 113  ARG B CB  1 
ATOM   4913 C  CG  . ARG B 1 121 ? 15.353  -14.409 22.96   1 16.01  ? 113  ARG B CG  1 
ATOM   4914 C  CD  . ARG B 1 121 ? 15.387  -15.933 22.776  1 14.629 ? 113  ARG B CD  1 
ATOM   4915 N  NE  . ARG B 1 121 ? 14.271  -16.721 23.316  1 17.235 ? 113  ARG B NE  1 
ATOM   4916 C  CZ  . ARG B 1 121 ? 14.198  -17.2   24.587  1 16.449 ? 113  ARG B CZ  1 
ATOM   4917 N  NH1 . ARG B 1 121 ? 15.11   -16.842 25.514  1 11.838 ? 113  ARG B NH1 1 
ATOM   4918 N  NH2 . ARG B 1 121 ? 13.182  -17.973 24.897  1 15.098 ? 113  ARG B NH2 1 
ATOM   4919 N  N   . GLN B 1 122 ? 16.11   -11.264 23.75   1 12.468 ? 114  GLN B N   1 
ATOM   4920 C  CA  . GLN B 1 122 ? 17.472  -10.769 23.765  1 12.613 ? 114  GLN B CA  1 
ATOM   4921 C  C   . GLN B 1 122 ? 18.393  -11.681 24.544  1 12.846 ? 114  GLN B C   1 
ATOM   4922 O  O   . GLN B 1 122 ? 17.977  -12.235 25.567  1 14.71  ? 114  GLN B O   1 
ATOM   4923 C  CB  . GLN B 1 122 ? 17.489  -9.363  24.288  1 12.331 ? 114  GLN B CB  1 
ATOM   4924 C  CG  . GLN B 1 122 ? 18.875  -8.775  24.106  1 13.266 ? 114  GLN B CG  1 
ATOM   4925 C  CD  . GLN B 1 122 ? 18.883  -7.281  24.191  1 15.834 ? 114  GLN B CD  1 
ATOM   4926 O  OE1 . GLN B 1 122 ? 17.889  -6.647  24.536  1 18.616 ? 114  GLN B OE1 1 
ATOM   4927 N  NE2 . GLN B 1 122 ? 20.077  -6.734  24      1 20.46  ? 114  GLN B NE2 1 
ATOM   4928 N  N   . ARG B 1 123 ? 19.598  -11.902 24.004  1 12.428 ? 115  ARG B N   1 
ATOM   4929 C  CA  . ARG B 1 123 ? 20.562  -12.797 24.628  1 12.465 ? 115  ARG B CA  1 
ATOM   4930 C  C   . ARG B 1 123 ? 22.002  -12.427 24.258  1 12.511 ? 115  ARG B C   1 
ATOM   4931 O  O   . ARG B 1 123 ? 22.356  -12.212 23.077  1 12.553 ? 115  ARG B O   1 
ATOM   4932 C  CB  . ARG B 1 123 ? 20.385  -14.291 24.362  1 13.248 ? 115  ARG B CB  1 
ATOM   4933 C  CG  . ARG B 1 123 ? 20.818  -15.233 25.455  1 16.121 ? 115  ARG B CG  1 
ATOM   4934 C  CD  . ARG B 1 123 ? 20.161  -16.55  25.107  1 15.578 ? 115  ARG B CD  1 
ATOM   4935 N  NE  . ARG B 1 123 ? 20.628  -17.539 26.099  1 19.023 ? 115  ARG B NE  1 
ATOM   4936 C  CZ  . ARG B 1 123 ? 20.199  -18.815 26.256  1 19.858 ? 115  ARG B CZ  1 
ATOM   4937 N  NH1 . ARG B 1 123 ? 19.276  -19.357 25.491  1 21.58  ? 115  ARG B NH1 1 
ATOM   4938 N  NH2 . ARG B 1 123 ? 20.678  -19.577 27.199  1 19.982 ? 115  ARG B NH2 1 
ATOM   4939 N  N   . PHE B 1 124 ? 22.862  -12.513 25.288  1 10.98  ? 116  PHE B N   1 
ATOM   4940 C  CA  . PHE B 1 124 ? 24.293  -12.307 24.991  1 12.335 ? 116  PHE B CA  1 
ATOM   4941 C  C   . PHE B 1 124 ? 24.86   -13.497 24.236  1 12.984 ? 116  PHE B C   1 
ATOM   4942 O  O   . PHE B 1 124 ? 24.45   -14.627 24.528  1 13.316 ? 116  PHE B O   1 
ATOM   4943 C  CB  . PHE B 1 124 ? 25.089  -12.268 26.289  1 10.1   ? 116  PHE B CB  1 
ATOM   4944 C  CG  . PHE B 1 124 ? 25.049  -10.872 26.882  1 12.547 ? 116  PHE B CG  1 
ATOM   4945 C  CD1 . PHE B 1 124 ? 25.738  -9.833  26.234  1 12.961 ? 116  PHE B CD1 1 
ATOM   4946 C  CD2 . PHE B 1 124 ? 24.476  -10.649 28.138  1 12.427 ? 116  PHE B CD2 1 
ATOM   4947 C  CE1 . PHE B 1 124 ? 25.706  -8.537  26.79   1 13.203 ? 116  PHE B CE1 1 
ATOM   4948 C  CE2 . PHE B 1 124 ? 24.489  -9.362  28.697  1 13.63  ? 116  PHE B CE2 1 
ATOM   4949 C  CZ  . PHE B 1 124 ? 25.172  -8.342  28.082  1 12.644 ? 116  PHE B CZ  1 
ATOM   4950 N  N   . VAL B 1 125 ? 25.751  -13.228 23.246  1 13.88  ? 117  VAL B N   1 
ATOM   4951 C  CA  . VAL B 1 125 ? 26.506  -14.3   22.598  1 12.914 ? 117  VAL B CA  1 
ATOM   4952 C  C   . VAL B 1 125 ? 27.444  -14.886 23.659  1 15.534 ? 117  VAL B C   1 
ATOM   4953 O  O   . VAL B 1 125 ? 28.144  -14.122 24.343  1 15.72  ? 117  VAL B O   1 
ATOM   4954 C  CB  . VAL B 1 125 ? 27.323  -13.83  21.383  1 14.351 ? 117  VAL B CB  1 
ATOM   4955 C  CG1 . VAL B 1 125 ? 28.038  -14.988 20.722  1 14.109 ? 117  VAL B CG1 1 
ATOM   4956 C  CG2 . VAL B 1 125 ? 26.404  -13.198 20.37   1 10.771 ? 117  VAL B CG2 1 
ATOM   4957 N  N   . GLU B 1 126 ? 27.436  -16.225 23.812  1 15.683 ? 118  GLU B N   1 
ATOM   4958 C  CA  . GLU B 1 126 ? 28.308  -16.819 24.814  1 15.403 ? 118  GLU B CA  1 
ATOM   4959 C  C   . GLU B 1 126 ? 29.695  -17.032 24.213  1 15.389 ? 118  GLU B C   1 
ATOM   4960 O  O   . GLU B 1 126 ? 30.178  -18.188 24.144  1 14.517 ? 118  GLU B O   1 
ATOM   4961 C  CB  . GLU B 1 126 ? 27.807  -18.186 25.3    1 18.198 ? 118  GLU B CB  1 
ATOM   4962 C  CG  . GLU B 1 126 ? 26.564  -18.115 26.17   1 20.469 ? 118  GLU B CG  1 
ATOM   4963 C  CD  . GLU B 1 126 ? 26.493  -19.497 26.85   1 28.921 ? 118  GLU B CD  1 
ATOM   4964 O  OE1 . GLU B 1 126 ? 27.199  -20.549 26.571  1 28.575 ? 118  GLU B OE1 1 
ATOM   4965 O  OE2 . GLU B 1 126 ? 25.636  -19.497 27.723  1 24.123 ? 118  GLU B OE2 1 
ATOM   4966 N  N   . THR B 1 127 ? 30.387  -15.934 23.861  1 14.116 ? 119  THR B N   1 
ATOM   4967 C  CA  . THR B 1 127 ? 31.773  -15.993 23.396  1 12.62  ? 119  THR B CA  1 
ATOM   4968 C  C   . THR B 1 127 ? 32.642  -16.509 24.548  1 12.482 ? 119  THR B C   1 
ATOM   4969 O  O   . THR B 1 127 ? 32.253  -16.334 25.726  1 11.923 ? 119  THR B O   1 
ATOM   4970 C  CB  . THR B 1 127 ? 32.263  -14.609 22.919  1 12.297 ? 119  THR B CB  1 
ATOM   4971 O  OG1 . THR B 1 127 ? 32.397  -13.825 24.103  1 12.118 ? 119  THR B OG1 1 
ATOM   4972 C  CG2 . THR B 1 127 ? 31.322  -13.912 21.948  1 12.707 ? 119  THR B CG2 1 
ATOM   4973 N  N   . ASP B 1 128 ? 33.837  -17.028 24.185  1 13.881 ? 120  ASP B N   1 
ATOM   4974 C  CA  . ASP B 1 128 ? 34.816  -17.422 25.177  1 16.617 ? 120  ASP B CA  1 
ATOM   4975 C  C   . ASP B 1 128 ? 35.066  -16.282 26.148  1 18.292 ? 120  ASP B C   1 
ATOM   4976 O  O   . ASP B 1 128 ? 35.129  -16.504 27.368  1 15.875 ? 120  ASP B O   1 
ATOM   4977 C  CB  . ASP B 1 128 ? 36.048  -18.045 24.55   1 16.73  ? 120  ASP B CB  1 
ATOM   4978 C  CG  . ASP B 1 128 ? 35.868  -19.468 24.074  1 16.861 ? 120  ASP B CG  1 
ATOM   4979 O  OD1 . ASP B 1 128 ? 34.818  -20.044 24.39   1 16.188 ? 120  ASP B OD1 1 
ATOM   4980 O  OD2 . ASP B 1 128 ? 36.799  -19.985 23.378  1 19.67  ? 120  ASP B OD2 1 
ATOM   4981 N  N   . ARG B 1 129 ? 35.258  -15.077 25.576  1 15.127 ? 121  ARG B N   1 
ATOM   4982 C  CA  . ARG B 1 129 ? 35.456  -13.882 26.38   1 15.595 ? 121  ARG B CA  1 
ATOM   4983 C  C   . ARG B 1 129 ? 34.334  -13.64  27.401  1 13.154 ? 121  ARG B C   1 
ATOM   4984 O  O   . ARG B 1 129 ? 34.61   -13.462 28.626  1 12.659 ? 121  ARG B O   1 
ATOM   4985 C  CB  . ARG B 1 129 ? 35.69   -12.713 25.433  1 18.009 ? 121  ARG B CB  1 
ATOM   4986 C  CG  . ARG B 1 129 ? 35.529  -11.343 26.091  1 15.286 ? 121  ARG B CG  1 
ATOM   4987 C  CD  . ARG B 1 129 ? 36.243  -10.395 25.179  1 14.628 ? 121  ARG B CD  1 
ATOM   4988 N  NE  . ARG B 1 129 ? 36.285  -8.988  25.626  1 13.124 ? 121  ARG B NE  1 
ATOM   4989 C  CZ  . ARG B 1 129 ? 36.925  -7.989  25.025  1 13.281 ? 121  ARG B CZ  1 
ATOM   4990 N  NH1 . ARG B 1 129 ? 37.634  -8.189  23.92   1 11.652 ? 121  ARG B NH1 1 
ATOM   4991 N  NH2 . ARG B 1 129 ? 36.775  -6.801  25.506  1 16.206 ? 121  ARG B NH2 1 
ATOM   4992 N  N   . PHE B 1 130 ? 33.089  -13.667 26.908  1 15.9   ? 122  PHE B N   1 
ATOM   4993 C  CA  . PHE B 1 130 ? 31.915  -13.496 27.745  1 12.875 ? 122  PHE B CA  1 
ATOM   4994 C  C   . PHE B 1 130 ? 31.892  -14.504 28.88   1 14.062 ? 122  PHE B C   1 
ATOM   4995 O  O   . PHE B 1 130 ? 31.565  -14.118 30.023  1 12.413 ? 122  PHE B O   1 
ATOM   4996 C  CB  . PHE B 1 130 ? 30.664  -13.591 26.879  1 16.54  ? 122  PHE B CB  1 
ATOM   4997 C  CG  . PHE B 1 130 ? 29.338  -13.622 27.657  1 14.493 ? 122  PHE B CG  1 
ATOM   4998 C  CD1 . PHE B 1 130 ? 28.731  -12.418 28.063  1 16.283 ? 122  PHE B CD1 1 
ATOM   4999 C  CD2 . PHE B 1 130 ? 28.74   -14.835 28.019  1 14.29  ? 122  PHE B CD2 1 
ATOM   5000 C  CE1 . PHE B 1 130 ? 27.523  -12.433 28.778  1 13.292 ? 122  PHE B CE1 1 
ATOM   5001 C  CE2 . PHE B 1 130 ? 27.515  -14.859 28.712  1 13.494 ? 122  PHE B CE2 1 
ATOM   5002 C  CZ  . PHE B 1 130 ? 26.911  -13.639 29.065  1 12.205 ? 122  PHE B CZ  1 
ATOM   5003 N  N   . LYS B 1 131 ? 32.178  -15.781 28.52   1 12.569 ? 123  LYS B N   1 
ATOM   5004 C  CA  . LYS B 1 131 ? 32.066  -16.829 29.525  1 14.605 ? 123  LYS B CA  1 
ATOM   5005 C  C   . LYS B 1 131 ? 33.054  -16.601 30.655  1 14.7   ? 123  LYS B C   1 
ATOM   5006 O  O   . LYS B 1 131 ? 32.705  -16.77  31.845  1 14.756 ? 123  LYS B O   1 
ATOM   5007 C  CB  . LYS B 1 131 ? 32.241  -18.22  28.892  1 14.867 ? 123  LYS B CB  1 
ATOM   5008 C  CG  . LYS B 1 131 ? 31.096  -18.587 27.854  1 14.422 ? 123  LYS B CG  1 
ATOM   5009 C  CD  . LYS B 1 131 ? 31.096  -20.085 27.573  1 16.221 ? 123  LYS B CD  1 
ATOM   5010 C  CE  . LYS B 1 131 ? 32.25   -20.676 26.897  1 18.466 ? 123  LYS B CE  1 
ATOM   5011 N  NZ  . LYS B 1 131 ? 33.265  -20.965 27.928  1 15.594 ? 123  LYS B NZ  1 
ATOM   5012 N  N   . VAL B 1 132 ? 34.314  -16.308 30.25   1 16.735 ? 124  VAL B N   1 
ATOM   5013 C  CA  . VAL B 1 132 ? 35.379  -16.068 31.199  1 17.993 ? 124  VAL B CA  1 
ATOM   5014 C  C   . VAL B 1 132 ? 34.924  -14.993 32.187  1 17.355 ? 124  VAL B C   1 
ATOM   5015 O  O   . VAL B 1 132 ? 35.028  -15.152 33.425  1 13.893 ? 124  VAL B O   1 
ATOM   5016 C  CB  . VAL B 1 132 ? 36.591  -15.658 30.319  1 23.375 ? 124  VAL B CB  1 
ATOM   5017 C  CG1 . VAL B 1 132 ? 37.362  -14.44  30.837  1 25.652 ? 124  VAL B CG1 1 
ATOM   5018 C  CG2 . VAL B 1 132 ? 37.423  -16.87  29.898  1 22.707 ? 124  VAL B CG2 1 
ATOM   5019 N  N   . GLU B 1 133 ? 34.525  -13.846 31.619  1 13.945 ? 125  GLU B N   1 
ATOM   5020 C  CA  . GLU B 1 133 ? 34.183  -12.674 32.42   1 15.738 ? 125  GLU B CA  1 
ATOM   5021 C  C   . GLU B 1 133 ? 32.955  -12.884 33.326  1 13.133 ? 125  GLU B C   1 
ATOM   5022 O  O   . GLU B 1 133 ? 32.943  -12.422 34.481  1 15.598 ? 125  GLU B O   1 
ATOM   5023 C  CB  . GLU B 1 133 ? 34.075  -11.416 31.528  1 15.148 ? 125  GLU B CB  1 
ATOM   5024 C  CG  . GLU B 1 133 ? 35.453  -10.934 31.051  1 15.415 ? 125  GLU B CG  1 
ATOM   5025 C  CD  . GLU B 1 133 ? 35.387  -9.586  30.308  1 15.794 ? 125  GLU B CD  1 
ATOM   5026 O  OE1 . GLU B 1 133 ? 34.302  -9      29.924  1 15.813 ? 125  GLU B OE1 1 
ATOM   5027 O  OE2 . GLU B 1 133 ? 36.478  -9.009  30.164  1 15.459 ? 125  GLU B OE2 1 
ATOM   5028 N  N   . ARG B 1 134 ? 31.957  -13.6   32.817  1 14.232 ? 126  ARG B N   1 
ATOM   5029 C  CA  . ARG B 1 134 ? 30.741  -13.959 33.522  1 14.494 ? 126  ARG B CA  1 
ATOM   5030 C  C   . ARG B 1 134 ? 31.128  -14.802 34.725  1 17.426 ? 126  ARG B C   1 
ATOM   5031 O  O   . ARG B 1 134 ? 30.744  -14.473 35.874  1 17.433 ? 126  ARG B O   1 
ATOM   5032 C  CB  . ARG B 1 134 ? 29.613  -14.517 32.616  1 14.294 ? 126  ARG B CB  1 
ATOM   5033 C  CG  . ARG B 1 134 ? 28.429  -14.632 33.581  1 15.656 ? 126  ARG B CG  1 
ATOM   5034 C  CD  . ARG B 1 134 ? 26.996  -14.769 32.933  1 12.976 ? 126  ARG B CD  1 
ATOM   5035 N  NE  . ARG B 1 134 ? 26.718  -13.391 32.549  1 14.287 ? 126  ARG B NE  1 
ATOM   5036 C  CZ  . ARG B 1 134 ? 25.529  -13.049 32.022  1 17.106 ? 126  ARG B CZ  1 
ATOM   5037 N  NH1 . ARG B 1 134 ? 24.646  -14.004 31.749  1 14.49  ? 126  ARG B NH1 1 
ATOM   5038 N  NH2 . ARG B 1 134 ? 25.287  -11.776 31.738  1 14.761 ? 126  ARG B NH2 1 
ATOM   5039 N  N   . ARG B 1 135 ? 31.93   -15.856 34.439  1 15.529 ? 127  ARG B N   1 
ATOM   5040 C  CA  . ARG B 1 135 ? 32.21   -16.805 35.502  1 18.816 ? 127  ARG B CA  1 
ATOM   5041 C  C   . ARG B 1 135 ? 33.037  -16.178 36.62   1 19.208 ? 127  ARG B C   1 
ATOM   5042 O  O   . ARG B 1 135 ? 32.732  -16.475 37.785  1 18.983 ? 127  ARG B O   1 
ATOM   5043 C  CB  . ARG B 1 135 ? 32.822  -18.053 34.892  1 17.219 ? 127  ARG B CB  1 
ATOM   5044 C  CG  . ARG B 1 135 ? 31.9    -18.92  34.058  1 18.174 ? 127  ARG B CG  1 
ATOM   5045 C  CD  . ARG B 1 135 ? 32.709  -19.941 33.306  1 18.333 ? 127  ARG B CD  1 
ATOM   5046 N  NE  . ARG B 1 135 ? 33.251  -20.944 34.221  1 23.65  ? 127  ARG B NE  1 
ATOM   5047 C  CZ  . ARG B 1 135 ? 32.604  -21.813 34.977  1 26.938 ? 127  ARG B CZ  1 
ATOM   5048 N  NH1 . ARG B 1 135 ? 31.405  -22.25  34.657  1 25.045 ? 127  ARG B NH1 1 
ATOM   5049 N  NH2 . ARG B 1 135 ? 33.216  -22.306 36.025  1 24.472 ? 127  ARG B NH2 1 
ATOM   5050 N  N   . ALA B 1 136 ? 33.989  -15.274 36.244  1 19.634 ? 128  ALA B N   1 
ATOM   5051 C  CA  . ALA B 1 136 ? 34.87   -14.54  37.153  1 21.709 ? 128  ALA B CA  1 
ATOM   5052 C  C   . ALA B 1 136 ? 34.2    -13.321 37.804  1 22.687 ? 128  ALA B C   1 
ATOM   5053 O  O   . ALA B 1 136 ? 34.738  -12.78  38.803  1 16.434 ? 128  ALA B O   1 
ATOM   5054 C  CB  . ALA B 1 136 ? 36.224  -14.165 36.543  1 19.875 ? 128  ALA B CB  1 
ATOM   5055 N  N   . ARG B 1 137 ? 33.025  -12.907 37.265  1 18.226 ? 129  ARG B N   1 
ATOM   5056 C  CA  . ARG B 1 137 ? 32.321  -11.692 37.619  1 15.145 ? 129  ARG B CA  1 
ATOM   5057 C  C   . ARG B 1 137 ? 33.32   -10.532 37.521  1 17.906 ? 129  ARG B C   1 
ATOM   5058 O  O   . ARG B 1 137 ? 33.388  -9.674  38.411  1 17.797 ? 129  ARG B O   1 
ATOM   5059 C  CB  . ARG B 1 137 ? 31.606  -11.853 38.988  1 21.063 ? 129  ARG B CB  1 
ATOM   5060 C  CG  . ARG B 1 137 ? 30.587  -10.768 39.305  1 22.167 ? 129  ARG B CG  1 
ATOM   5061 C  CD  . ARG B 1 137 ? 30.441  -10.239 40.741  1 32.312 ? 129  ARG B CD  1 
ATOM   5062 N  NE  . ARG B 1 137 ? 30.017  -8.833  40.949  1 29.33  ? 129  ARG B NE  1 
ATOM   5063 C  CZ  . ARG B 1 137 ? 29.896  -8.168  42.11   1 31.624 ? 129  ARG B CZ  1 
ATOM   5064 N  NH1 . ARG B 1 137 ? 30.48   -8.61   43.207  1 31.472 ? 129  ARG B NH1 1 
ATOM   5065 N  NH2 . ARG B 1 137 ? 29.213  -7.031  42.194  1 28.209 ? 129  ARG B NH2 1 
ATOM   5066 N  N   . LYS B 1 138 ? 34.096  -10.488 36.416  1 16.546 ? 130  LYS B N   1 
ATOM   5067 C  CA  . LYS B 1 138 ? 35.269  -9.625  36.378  1 21.174 ? 130  LYS B CA  1 
ATOM   5068 C  C   . LYS B 1 138 ? 35.739  -9.424  34.952  1 17.231 ? 130  LYS B C   1 
ATOM   5069 O  O   . LYS B 1 138 ? 35.904  -10.398 34.223  1 16.54  ? 130  LYS B O   1 
ATOM   5070 C  CB  . LYS B 1 138 ? 36.416  -10.148 37.242  1 27.096 ? 130  LYS B CB  1 
ATOM   5071 C  CG  . LYS B 1 138 ? 37.45   -9.082  37.649  1 43.885 ? 130  LYS B CG  1 
ATOM   5072 C  CD  . LYS B 1 138 ? 36.981  -8.063  38.692  1 46.619 ? 130  LYS B CD  1 
ATOM   5073 C  CE  . LYS B 1 138 ? 38.088  -7.47   39.492  1 49.136 ? 130  LYS B CE  1 
ATOM   5074 N  NZ  . LYS B 1 138 ? 38.908  -6.6    38.647  1 55.385 ? 130  LYS B NZ  1 
ATOM   5075 N  N   . SER B 1 139 ? 35.99   -8.15   34.629  1 16.589 ? 131  SER B N   1 
ATOM   5076 C  CA  . SER B 1 139 ? 36.65   -7.803  33.358  1 14.363 ? 131  SER B CA  1 
ATOM   5077 C  C   . SER B 1 139 ? 38.064  -8.396  33.349  1 14.573 ? 131  SER B C   1 
ATOM   5078 O  O   . SER B 1 139 ? 38.726  -8.389  34.381  1 17.01  ? 131  SER B O   1 
ATOM   5079 C  CB  . SER B 1 139 ? 36.712  -6.28   33.175  1 13.827 ? 131  SER B CB  1 
ATOM   5080 O  OG  . SER B 1 139 ? 37.67   -5.867  32.189  1 15.185 ? 131  SER B OG  1 
ATOM   5081 N  N   . MET B 1 140 ? 38.46   -9.015  32.228  1 14.163 ? 132  MET B N   1 
ATOM   5082 C  CA  . MET B 1 140 ? 39.737  -9.7    32.066  1 14.938 ? 132  MET B CA  1 
ATOM   5083 C  C   . MET B 1 140 ? 40.314  -9.366  30.68   1 19.971 ? 132  MET B C   1 
ATOM   5084 O  O   . MET B 1 140 ? 41.264  -10.016 30.263  1 17.93  ? 132  MET B O   1 
ATOM   5085 C  CB  . MET B 1 140 ? 39.479  -11.206 32.087  1 17.107 ? 132  MET B CB  1 
ATOM   5086 C  CG  . MET B 1 140 ? 38.904  -11.661 33.441  1 22.27  ? 132  MET B CG  1 
ATOM   5087 S  SD  . MET B 1 140 ? 38.86   -13.404 33.843  1 24.719 ? 132  MET B SD  1 
ATOM   5088 C  CE  . MET B 1 140 ? 40.608  -13.838 33.974  1 28.892 ? 132  MET B CE  1 
ATOM   5089 N  N   . TYR B 1 141 ? 39.697  -8.396  29.985  1 18.212 ? 133  TYR B N   1 
ATOM   5090 C  CA  . TYR B 1 141 ? 40.131  -8.003  28.636  1 18.056 ? 133  TYR B CA  1 
ATOM   5091 C  C   . TYR B 1 141 ? 40.43   -6.505  28.619  1 16.702 ? 133  TYR B C   1 
ATOM   5092 O  O   . TYR B 1 141 ? 39.756  -5.757  29.331  1 15.986 ? 133  TYR B O   1 
ATOM   5093 C  CB  . TYR B 1 141 ? 39.136  -8.481  27.594  1 13.418 ? 133  TYR B CB  1 
ATOM   5094 C  CG  . TYR B 1 141 ? 39.136  -9.978  27.391  1 14.421 ? 133  TYR B CG  1 
ATOM   5095 C  CD1 . TYR B 1 141 ? 38.375  -10.809 28.214  1 14.666 ? 133  TYR B CD1 1 
ATOM   5096 C  CD2 . TYR B 1 141 ? 39.879  -10.571 26.365  1 15.208 ? 133  TYR B CD2 1 
ATOM   5097 C  CE1 . TYR B 1 141 ? 38.337  -12.19  27.997  1 13.358 ? 133  TYR B CE1 1 
ATOM   5098 C  CE2 . TYR B 1 141 ? 39.894  -11.955 26.169  1 14.879 ? 133  TYR B CE2 1 
ATOM   5099 C  CZ  . TYR B 1 141 ? 39.051  -12.753 26.935  1 13.183 ? 133  TYR B CZ  1 
ATOM   5100 O  OH  . TYR B 1 141 ? 38.977  -14.108 26.76   1 10.658 ? 133  TYR B OH  1 
ATOM   5101 N  N   . GLY B 1 142 ? 41.514  -6.107  27.922  1 11.731 ? 134  GLY B N   1 
ATOM   5102 C  CA  . GLY B 1 142 ? 41.863  -4.693  27.806  1 12.984 ? 134  GLY B CA  1 
ATOM   5103 C  C   . GLY B 1 142 ? 41.393  -4.119  26.47   1 13.615 ? 134  GLY B C   1 
ATOM   5104 O  O   . GLY B 1 142 ? 40.198  -4.105  26.166  1 16.111 ? 134  GLY B O   1 
ATOM   5105 N  N   . LEU B 1 143 ? 42.348  -3.506  25.775  1 14.337 ? 135  LEU B N   1 
ATOM   5106 C  CA  . LEU B 1 143 ? 42.054  -2.681  24.605  1 14.583 ? 135  LEU B CA  1 
ATOM   5107 C  C   . LEU B 1 143 ? 41.52   -3.526  23.439  1 14.522 ? 135  LEU B C   1 
ATOM   5108 O  O   . LEU B 1 143 ? 41.849  -4.702  23.283  1 13.404 ? 135  LEU B O   1 
ATOM   5109 C  CB  . LEU B 1 143 ? 43.291  -1.854  24.158  1 15.666 ? 135  LEU B CB  1 
ATOM   5110 C  CG  . LEU B 1 143 ? 43.966  -0.927  25.177  1 16.457 ? 135  LEU B CG  1 
ATOM   5111 C  CD1 . LEU B 1 143 ? 45.104  -0.103  24.414  1 13.989 ? 135  LEU B CD1 1 
ATOM   5112 C  CD2 . LEU B 1 143 ? 42.814  0.014   25.578  1 13.146 ? 135  LEU B CD2 1 
ATOM   5113 N  N   . TYR B 1 144 ? 40.713  -2.851  22.603  1 15.85  ? 136  TYR B N   1 
ATOM   5114 C  CA  . TYR B 1 144 ? 40.242  -3.474  21.365  1 13.07  ? 136  TYR B CA  1 
ATOM   5115 C  C   . TYR B 1 144 ? 41.388  -4.151  20.652  1 10.458 ? 136  TYR B C   1 
ATOM   5116 O  O   . TYR B 1 144 ? 42.334  -3.477  20.245  1 14.549 ? 136  TYR B O   1 
ATOM   5117 C  CB  . TYR B 1 144 ? 39.771  -2.379  20.426  1 11.37  ? 136  TYR B CB  1 
ATOM   5118 C  CG  . TYR B 1 144 ? 39.19   -2.88   19.109  1 11.341 ? 136  TYR B CG  1 
ATOM   5119 C  CD1 . TYR B 1 144 ? 37.963  -3.576  19.122  1 12.231 ? 136  TYR B CD1 1 
ATOM   5120 C  CD2 . TYR B 1 144 ? 39.817  -2.598  17.898  1 10.363 ? 136  TYR B CD2 1 
ATOM   5121 C  CE1 . TYR B 1 144 ? 37.385  -3.974  17.907  1 13.261 ? 136  TYR B CE1 1 
ATOM   5122 C  CE2 . TYR B 1 144 ? 39.24   -2.954  16.687  1 10.243 ? 136  TYR B CE2 1 
ATOM   5123 C  CZ  . TYR B 1 144 ? 38.035  -3.668  16.722  1 12.518 ? 136  TYR B CZ  1 
ATOM   5124 O  OH  . TYR B 1 144 ? 37.437  -4.044  15.548  1 13.951 ? 136  TYR B OH  1 
ATOM   5125 N  N   . ARG B 1 145 ? 41.281  -5.466  20.427  1 11.647 ? 137  ARG B N   1 
ATOM   5126 C  CA  . ARG B 1 145 ? 42.177  -6.267  19.603  1 13.542 ? 137  ARG B CA  1 
ATOM   5127 C  C   . ARG B 1 145 ? 43.634  -6.191  20.1    1 14.754 ? 137  ARG B C   1 
ATOM   5128 O  O   . ARG B 1 145 ? 44.56   -6.275  19.289  1 14.149 ? 137  ARG B O   1 
ATOM   5129 C  CB  . ARG B 1 145 ? 42.069  -5.909  18.1    1 12.267 ? 137  ARG B CB  1 
ATOM   5130 C  CG  . ARG B 1 145 ? 40.655  -6.146  17.582  1 12.523 ? 137  ARG B CG  1 
ATOM   5131 C  CD  . ARG B 1 145 ? 40.772  -6.038  16.008  1 11.673 ? 137  ARG B CD  1 
ATOM   5132 N  NE  . ARG B 1 145 ? 41.531  -7.154  15.443  1 11.397 ? 137  ARG B NE  1 
ATOM   5133 C  CZ  . ARG B 1 145 ? 41.484  -7.571  14.152  1 14.814 ? 137  ARG B CZ  1 
ATOM   5134 N  NH1 . ARG B 1 145 ? 40.725  -6.932  13.282  1 11.05  ? 137  ARG B NH1 1 
ATOM   5135 N  NH2 . ARG B 1 145 ? 42.074  -8.732  13.799  1 16.698 ? 137  ARG B NH2 1 
ATOM   5136 N  N   . ASN B 1 146 ? 43.848  -6.041  21.442  1 14.586 ? 138  ASN B N   1 
ATOM   5137 C  CA  . ASN B 1 146 ? 45.2    -6.066  21.923  1 13.066 ? 138  ASN B CA  1 
ATOM   5138 C  C   . ASN B 1 146 ? 45.352  -7.11   23.027  1 13.094 ? 138  ASN B C   1 
ATOM   5139 O  O   . ASN B 1 146 ? 45.248  -6.725  24.195  1 12.206 ? 138  ASN B O   1 
ATOM   5140 C  CB  . ASN B 1 146 ? 45.663  -4.679  22.387  1 14.007 ? 138  ASN B CB  1 
ATOM   5141 C  CG  . ASN B 1 146 ? 47.154  -4.674  22.616  1 12.823 ? 138  ASN B CG  1 
ATOM   5142 O  OD1 . ASN B 1 146 ? 47.788  -5.724  22.539  1 14.576 ? 138  ASN B OD1 1 
ATOM   5143 N  ND2 . ASN B 1 146 ? 47.738  -3.517  22.831  1 14.139 ? 138  ASN B ND2 1 
ATOM   5144 N  N   . PRO B 1 147 ? 45.656  -8.395  22.716  1 14.28  ? 139  PRO B N   1 
ATOM   5145 C  CA  . PRO B 1 147 ? 45.994  -9.38   23.731  1 14.04  ? 139  PRO B CA  1 
ATOM   5146 C  C   . PRO B 1 147 ? 47.084  -8.998  24.741  1 15.847 ? 139  PRO B C   1 
ATOM   5147 O  O   . PRO B 1 147 ? 47.084  -9.493  25.871  1 14.542 ? 139  PRO B O   1 
ATOM   5148 C  CB  . PRO B 1 147 ? 46.299  -10.617 22.936  1 17.208 ? 139  PRO B CB  1 
ATOM   5149 C  CG  . PRO B 1 147 ? 45.742  -10.42  21.549  1 15.316 ? 139  PRO B CG  1 
ATOM   5150 C  CD  . PRO B 1 147 ? 45.58   -8.975  21.355  1 13.015 ? 139  PRO B CD  1 
ATOM   5151 N  N   . TYR B 1 148 ? 48.003  -8.09   24.358  1 16.399 ? 140  TYR B N   1 
ATOM   5152 C  CA  . TYR B 1 148 ? 49.094  -7.656  25.249  1 21.157 ? 140  TYR B CA  1 
ATOM   5153 C  C   . TYR B 1 148 ? 48.553  -6.824  26.434  1 21.179 ? 140  TYR B C   1 
ATOM   5154 O  O   . TYR B 1 148 ? 49.272  -6.543  27.408  1 16.916 ? 140  TYR B O   1 
ATOM   5155 C  CB  . TYR B 1 148 ? 50.177  -6.932  24.435  1 15.911 ? 140  TYR B CB  1 
ATOM   5156 C  CG  . TYR B 1 148 ? 50.848  -7.895  23.448  1 15.549 ? 140  TYR B CG  1 
ATOM   5157 C  CD1 . TYR B 1 148 ? 51.772  -8.877  23.86   1 12.207 ? 140  TYR B CD1 1 
ATOM   5158 C  CD2 . TYR B 1 148 ? 50.527  -7.8    22.092  1 13.91  ? 140  TYR B CD2 1 
ATOM   5159 C  CE1 . TYR B 1 148 ? 52.345  -9.768  22.965  1 11.98  ? 140  TYR B CE1 1 
ATOM   5160 C  CE2 . TYR B 1 148 ? 51.121  -8.652  21.186  1 13.063 ? 140  TYR B CE2 1 
ATOM   5161 C  CZ  . TYR B 1 148 ? 51.98   -9.644  21.628  1 10.368 ? 140  TYR B CZ  1 
ATOM   5162 O  OH  . TYR B 1 148 ? 52.429  -10.407 20.631  1 11.212 ? 140  TYR B OH  1 
ATOM   5163 N  N   . THR B 1 149 ? 47.276  -6.418  26.345  1 17.478 ? 141  THR B N   1 
ATOM   5164 C  CA  . THR B 1 149 ? 46.534  -5.694  27.382  1 19.05  ? 141  THR B CA  1 
ATOM   5165 C  C   . THR B 1 149 ? 45.428  -6.553  28.048  1 16.587 ? 141  THR B C   1 
ATOM   5166 O  O   . THR B 1 149 ? 44.698  -6.06   28.908  1 16.281 ? 141  THR B O   1 
ATOM   5167 C  CB  . THR B 1 149 ? 45.973  -4.357  26.879  1 18.003 ? 141  THR B CB  1 
ATOM   5168 O  OG1 . THR B 1 149 ? 44.973  -4.633  25.898  1 18.575 ? 141  THR B OG1 1 
ATOM   5169 C  CG2 . THR B 1 149 ? 47.058  -3.452  26.313  1 17.051 ? 141  THR B CG2 1 
ATOM   5170 N  N   . HIS B 1 150 ? 45.374  -7.842  27.767  1 15.229 ? 142  HIS B N   1 
ATOM   5171 C  CA  . HIS B 1 150 ? 44.395  -8.725  28.395  1 16.818 ? 142  HIS B CA  1 
ATOM   5172 C  C   . HIS B 1 150 ? 45.034  -9.353  29.621  1 17.884 ? 142  HIS B C   1 
ATOM   5173 O  O   . HIS B 1 150 ? 46.286  -9.296  29.802  1 19.51  ? 142  HIS B O   1 
ATOM   5174 C  CB  . HIS B 1 150 ? 43.807  -9.779  27.436  1 13.887 ? 142  HIS B CB  1 
ATOM   5175 C  CG  . HIS B 1 150 ? 43.137  -9.147  26.262  1 14.644 ? 142  HIS B CG  1 
ATOM   5176 N  ND1 . HIS B 1 150 ? 43.083  -9.787  25.048  1 14.071 ? 142  HIS B ND1 1 
ATOM   5177 C  CD2 . HIS B 1 150 ? 42.6    -7.981  26.079  1 11.674 ? 142  HIS B CD2 1 
ATOM   5178 C  CE1 . HIS B 1 150 ? 42.379  -9.053  24.189  1 12.768 ? 142  HIS B CE1 1 
ATOM   5179 N  NE2 . HIS B 1 150 ? 42.089  -7.958  24.797  1 17.133 ? 142  HIS B NE2 1 
ATOM   5180 N  N   . HIS B 1 151 ? 44.149  -9.994  30.426  1 17.083 ? 143  HIS B N   1 
ATOM   5181 C  CA  . HIS B 1 151 ? 44.605  -10.733 31.586  1 19.608 ? 143  HIS B CA  1 
ATOM   5182 C  C   . HIS B 1 151 ? 45.469  -11.918 31.126  1 18.623 ? 143  HIS B C   1 
ATOM   5183 O  O   . HIS B 1 151 ? 45.113  -12.587 30.126  1 17.3   ? 143  HIS B O   1 
ATOM   5184 C  CB  . HIS B 1 151 ? 43.393  -11.249 32.355  1 15.869 ? 143  HIS B CB  1 
ATOM   5185 C  CG  . HIS B 1 151 ? 43.671  -11.876 33.685  1 15.074 ? 143  HIS B CG  1 
ATOM   5186 N  ND1 . HIS B 1 151 ? 44.166  -13.131 33.794  1 15.303 ? 143  HIS B ND1 1 
ATOM   5187 C  CD2 . HIS B 1 151 ? 43.39   -11.481 34.912  1 13.365 ? 143  HIS B CD2 1 
ATOM   5188 C  CE1 . HIS B 1 151 ? 44.166  -13.498 35.076  1 14.198 ? 143  HIS B CE1 1 
ATOM   5189 N  NE2 . HIS B 1 151 ? 43.715  -12.507 35.791  1 13.02  ? 143  HIS B NE2 1 
ATOM   5190 N  N   . PRO B 1 152 ? 46.618  -12.211 31.803  1 17.7   ? 144  PRO B N   1 
ATOM   5191 C  CA  . PRO B 1 152 ? 47.513  -13.318 31.459  1 17.622 ? 144  PRO B CA  1 
ATOM   5192 C  C   . PRO B 1 152 ? 46.805  -14.645 31.185  1 19.448 ? 144  PRO B C   1 
ATOM   5193 O  O   . PRO B 1 152 ? 47.116  -15.332 30.188  1 18.159 ? 144  PRO B O   1 
ATOM   5194 C  CB  . PRO B 1 152 ? 48.289  -13.496 32.763  1 19.186 ? 144  PRO B CB  1 
ATOM   5195 C  CG  . PRO B 1 152 ? 48.509  -12.022 33.023  1 22.52  ? 144  PRO B CG  1 
ATOM   5196 C  CD  . PRO B 1 152 ? 47.117  -11.537 33.022  1 18.794 ? 144  PRO B CD  1 
ATOM   5197 N  N   . CYS B 1 153 ? 45.758  -14.928 31.972  1 16.269 ? 145  CYS B N   1 
ATOM   5198 C  CA  . CYS B 1 153 ? 45.032  -16.18  31.832  1 17.251 ? 145  CYS B CA  1 
ATOM   5199 C  C   . CYS B 1 153 ? 44.214  -16.255 30.531  1 17.404 ? 145  CYS B C   1 
ATOM   5200 O  O   . CYS B 1 153 ? 43.884  -17.351 30.126  1 19.094 ? 145  CYS B O   1 
ATOM   5201 C  CB  . CYS B 1 153 ? 44.088  -16.467 32.975  1 17.068 ? 145  CYS B CB  1 
ATOM   5202 S  SG  . CYS B 1 153 ? 44.961  -16.683 34.575  1 31.033 ? 145  CYS B SG  1 
ATOM   5203 N  N   . VAL B 1 154 ? 43.933  -15.125 29.879  1 20.285 ? 146  VAL B N   1 
ATOM   5204 C  CA  . VAL B 1 154 ? 43.084  -15.138 28.689  1 18.84  ? 146  VAL B CA  1 
ATOM   5205 C  C   . VAL B 1 154 ? 43.805  -14.656 27.438  1 19.798 ? 146  VAL B C   1 
ATOM   5206 O  O   . VAL B 1 154 ? 43.178  -14.597 26.373  1 15.158 ? 146  VAL B O   1 
ATOM   5207 C  CB  . VAL B 1 154 ? 41.709  -14.441 28.867  1 20.306 ? 146  VAL B CB  1 
ATOM   5208 C  CG1 . VAL B 1 154 ? 40.887  -15.177 29.913  1 22.254 ? 146  VAL B CG1 1 
ATOM   5209 C  CG2 . VAL B 1 154 ? 41.866  -12.94  29.136  1 16.301 ? 146  VAL B CG2 1 
ATOM   5210 N  N   . ARG B 1 155 ? 45.13   -14.417 27.512  1 18.483 ? 147  ARG B N   1 
ATOM   5211 C  CA  . ARG B 1 155 ? 45.824  -13.861 26.375  1 17.065 ? 147  ARG B CA  1 
ATOM   5212 C  C   . ARG B 1 155 ? 45.705  -14.732 25.139  1 18.352 ? 147  ARG B C   1 
ATOM   5213 O  O   . ARG B 1 155 ? 45.635  -14.19  24.039  1 18.219 ? 147  ARG B O   1 
ATOM   5214 C  CB  . ARG B 1 155 ? 47.339  -13.803 26.597  1 22.896 ? 147  ARG B CB  1 
ATOM   5215 C  CG  . ARG B 1 155 ? 47.723  -12.538 27.33   1 26.715 ? 147  ARG B CG  1 
ATOM   5216 C  CD  . ARG B 1 155 ? 49.221  -12.208 27.179  1 29.331 ? 147  ARG B CD  1 
ATOM   5217 N  NE  . ARG B 1 155 ? 49.278  -11.281 28.318  1 33.385 ? 147  ARG B NE  1 
ATOM   5218 C  CZ  . ARG B 1 155 ? 49.659  -10.033 28.334  1 45.763 ? 147  ARG B CZ  1 
ATOM   5219 N  NH1 . ARG B 1 155 ? 50.63   -9.649  27.529  1 53.772 ? 147  ARG B NH1 1 
ATOM   5220 N  NH2 . ARG B 1 155 ? 49.188  -9.22   29.27   1 48.939 ? 147  ARG B NH2 1 
ATOM   5221 N  N   . GLN B 1 156 ? 45.68   -16.068 25.339  1 19.233 ? 148  GLN B N   1 
ATOM   5222 C  CA  . GLN B 1 156 ? 45.67   -17.012 24.231  1 20.983 ? 148  GLN B CA  1 
ATOM   5223 C  C   . GLN B 1 156 ? 44.247  -17.528 23.939  1 18.225 ? 148  GLN B C   1 
ATOM   5224 O  O   . GLN B 1 156 ? 44.065  -18.619 23.382  1 23.916 ? 148  GLN B O   1 
ATOM   5225 C  CB  . GLN B 1 156 ? 46.766  -18.075 24.444  1 21.695 ? 148  GLN B CB  1 
ATOM   5226 C  CG  . GLN B 1 156 ? 47.374  -18.433 23.09   1 27.951 ? 148  GLN B CG  1 
ATOM   5227 C  CD  . GLN B 1 156 ? 48.646  -19.253 23.126  1 32.549 ? 148  GLN B CD  1 
ATOM   5228 O  OE1 . GLN B 1 156 ? 49.212  -19.555 24.176  1 29.843 ? 148  GLN B OE1 1 
ATOM   5229 N  NE2 . GLN B 1 156 ? 49.121  -19.587 21.938  1 38.076 ? 148  GLN B NE2 1 
ATOM   5230 N  N   . THR B 1 157 ? 43.252  -16.696 24.231  1 16.258 ? 149  THR B N   1 
ATOM   5231 C  CA  . THR B 1 157 ? 41.855  -17.032 23.982  1 14.326 ? 149  THR B CA  1 
ATOM   5232 C  C   . THR B 1 157 ? 41.472  -16.392 22.634  1 15.311 ? 149  THR B C   1 
ATOM   5233 O  O   . THR B 1 157 ? 42.161  -15.487 22.151  1 14.299 ? 149  THR B O   1 
ATOM   5234 C  CB  . THR B 1 157 ? 40.905  -16.601 25.091  1 12.081 ? 149  THR B CB  1 
ATOM   5235 O  OG1 . THR B 1 157 ? 41.121  -15.181 25.19   1 15.599 ? 149  THR B OG1 1 
ATOM   5236 C  CG2 . THR B 1 157 ? 41.022  -17.451 26.352  1 13.342 ? 149  THR B CG2 1 
ATOM   5237 N  N   . VAL B 1 158 ? 40.384  -16.85  22.067  1 12.643 ? 150  VAL B N   1 
ATOM   5238 C  CA  . VAL B 1 158 ? 39.646  -16.017 21.072  1 17.722 ? 150  VAL B CA  1 
ATOM   5239 C  C   . VAL B 1 158 ? 39.037  -14.821 21.836  1 13.94  ? 150  VAL B C   1 
ATOM   5240 O  O   . VAL B 1 158 ? 38.31   -15.028 22.81   1 15.115 ? 150  VAL B O   1 
ATOM   5241 C  CB  . VAL B 1 158 ? 38.566  -16.784 20.267  1 16.202 ? 150  VAL B CB  1 
ATOM   5242 C  CG1 . VAL B 1 158 ? 37.729  -15.885 19.37   1 12.376 ? 150  VAL B CG1 1 
ATOM   5243 C  CG2 . VAL B 1 158 ? 39.173  -17.875 19.381  1 19.805 ? 150  VAL B CG2 1 
ATOM   5244 N  N   . GLU B 1 159 ? 39.421  -13.593 21.451  1 11.161 ? 151  GLU B N   1 
ATOM   5245 C  CA  . GLU B 1 159 ? 39.115  -12.353 22.153  1 12.206 ? 151  GLU B CA  1 
ATOM   5246 C  C   . GLU B 1 159 ? 37.872  -11.635 21.587  1 14.601 ? 151  GLU B C   1 
ATOM   5247 O  O   . GLU B 1 159 ? 37.477  -10.563 22.057  1 14.728 ? 151  GLU B O   1 
ATOM   5248 C  CB  . GLU B 1 159 ? 40.39   -11.484 22.098  1 13.279 ? 151  GLU B CB  1 
ATOM   5249 C  CG  . GLU B 1 159 ? 40.694  -11.074 20.657  1 13.857 ? 151  GLU B CG  1 
ATOM   5250 C  CD  . GLU B 1 159 ? 41.371  -9.729  20.465  1 16.959 ? 151  GLU B CD  1 
ATOM   5251 O  OE1 . GLU B 1 159 ? 41.684  -9.063  21.471  1 16.14  ? 151  GLU B OE1 1 
ATOM   5252 O  OE2 . GLU B 1 159 ? 41.56   -9.352  19.282  1 17.079 ? 151  GLU B OE2 1 
ATOM   5253 N  N   . SER B 1 160 ? 37.287  -12.212 20.521  1 14.444 ? 152  SER B N   1 
ATOM   5254 C  CA  . SER B 1 160 ? 36.099  -11.68  19.869  1 14.516 ? 152  SER B CA  1 
ATOM   5255 C  C   . SER B 1 160 ? 34.911  -11.548 20.829  1 14.366 ? 152  SER B C   1 
ATOM   5256 O  O   . SER B 1 160 ? 34.571  -12.462 21.566  1 14.468 ? 152  SER B O   1 
ATOM   5257 C  CB  . SER B 1 160 ? 35.729  -12.56  18.684  1 13.107 ? 152  SER B CB  1 
ATOM   5258 O  OG  . SER B 1 160 ? 34.42   -12.206 18.25   1 10.955 ? 152  SER B OG  1 
ATOM   5259 N  N   . THR B 1 161 ? 34.279  -10.375 20.81   1 11.837 ? 153  THR B N   1 
ATOM   5260 C  CA  . THR B 1 161 ? 33.004  -10.17  21.485  1 12.651 ? 153  THR B CA  1 
ATOM   5261 C  C   . THR B 1 161 ? 31.813  -10.435 20.538  1 13.008 ? 153  THR B C   1 
ATOM   5262 O  O   . THR B 1 161 ? 30.691  -10.163 20.896  1 13.89  ? 153  THR B O   1 
ATOM   5263 C  CB  . THR B 1 161 ? 32.912  -8.778  22.114  1 11.293 ? 153  THR B CB  1 
ATOM   5264 O  OG1 . THR B 1 161 ? 33.333  -7.885  21.089  1 11.422 ? 153  THR B OG1 1 
ATOM   5265 C  CG2 . THR B 1 161 ? 33.775  -8.586  23.368  1 11.41  ? 153  THR B CG2 1 
ATOM   5266 N  N   . ALA B 1 162 ? 32.063  -10.801 19.265  1 12.486 ? 154  ALA B N   1 
ATOM   5267 C  CA  . ALA B 1 162 ? 31.017  -11.221 18.356  1 11.798 ? 154  ALA B CA  1 
ATOM   5268 C  C   . ALA B 1 162 ? 29.846  -10.244 18.379  1 12.297 ? 154  ALA B C   1 
ATOM   5269 O  O   . ALA B 1 162 ? 28.719  -10.652 18.659  1 12.944 ? 154  ALA B O   1 
ATOM   5270 C  CB  . ALA B 1 162 ? 30.555  -12.639 18.696  1 12.87  ? 154  ALA B CB  1 
ATOM   5271 N  N   . ASN B 1 163 ? 30.09   -8.988  17.992  1 12.029 ? 155  ASN B N   1 
ATOM   5272 C  CA  . ASN B 1 163 ? 29.136  -7.932  18.342  1 11.071 ? 155  ASN B CA  1 
ATOM   5273 C  C   . ASN B 1 163 ? 28.771  -7.003  17.203  1 10.9   ? 155  ASN B C   1 
ATOM   5274 O  O   . ASN B 1 163 ? 28.165  -5.953  17.475  1 11.588 ? 155  ASN B O   1 
ATOM   5275 C  CB  . ASN B 1 163 ? 29.636  -7.132  19.54   1 15.265 ? 155  ASN B CB  1 
ATOM   5276 C  CG  . ASN B 1 163 ? 30.84   -6.274  19.207  1 13.139 ? 155  ASN B CG  1 
ATOM   5277 O  OD1 . ASN B 1 163 ? 31.38   -6.31   18.096  1 10.843 ? 155  ASN B OD1 1 
ATOM   5278 N  ND2 . ASN B 1 163 ? 31.176  -5.414  20.147  1 10.281 ? 155  ASN B ND2 1 
ATOM   5279 N  N   . THR B 1 164 ? 29.023  -7.42   15.944  1 14.617 ? 156  THR B N   1 
ATOM   5280 C  CA  . THR B 1 164 ? 28.946  -6.504  14.793  1 13.187 ? 156  THR B CA  1 
ATOM   5281 C  C   . THR B 1 164 ? 27.828  -6.845  13.809  1 13.3   ? 156  THR B C   1 
ATOM   5282 O  O   . THR B 1 164 ? 27.112  -5.935  13.357  1 10.151 ? 156  THR B O   1 
ATOM   5283 C  CB  . THR B 1 164 ? 30.335  -6.558  14.116  1 18.2   ? 156  THR B CB  1 
ATOM   5284 O  OG1 . THR B 1 164 ? 31.302  -6.156  15.062  1 18.482 ? 156  THR B OG1 1 
ATOM   5285 C  CG2 . THR B 1 164 ? 30.441  -5.903  12.759  1 20.074 ? 156  THR B CG2 1 
ATOM   5286 N  N   . ASN B 1 165 ? 27.602  -8.13   13.513  1 10.443 ? 157  ASN B N   1 
ATOM   5287 C  CA  . ASN B 1 165 ? 26.663  -8.498  12.483  1 12.178 ? 157  ASN B CA  1 
ATOM   5288 C  C   . ASN B 1 165 ? 26.225  -9.939  12.675  1 12.863 ? 157  ASN B C   1 
ATOM   5289 O  O   . ASN B 1 165 ? 26.862  -10.713 13.397  1 12.5   ? 157  ASN B O   1 
ATOM   5290 C  CB  . ASN B 1 165 ? 27.257  -8.207  11.109  1 9.336  ? 157  ASN B CB  1 
ATOM   5291 C  CG  . ASN B 1 165 ? 26.25   -8.172  9.981   1 12.247 ? 157  ASN B CG  1 
ATOM   5292 O  OD1 . ASN B 1 165 ? 25.025  -8.132  10.167  1 11.623 ? 157  ASN B OD1 1 
ATOM   5293 N  ND2 . ASN B 1 165 ? 26.763  -8.245  8.766   1 12.131 ? 157  ASN B ND2 1 
ATOM   5294 N  N   . VAL B 1 166 ? 25.111  -10.28  12.002  1 13.314 ? 158  VAL B N   1 
ATOM   5295 C  CA  . VAL B 1 166 ? 24.528  -11.593 12.081  1 12.607 ? 158  VAL B CA  1 
ATOM   5296 C  C   . VAL B 1 166 ? 24.238  -12.039 10.633  1 12.995 ? 158  VAL B C   1 
ATOM   5297 O  O   . VAL B 1 166 ? 24.147  -11.193 9.756   1 10.58  ? 158  VAL B O   1 
ATOM   5298 C  CB  . VAL B 1 166 ? 23.275  -11.696 12.948  1 11.239 ? 158  VAL B CB  1 
ATOM   5299 C  CG1 . VAL B 1 166 ? 23.564  -11.354 14.399  1 11.131 ? 158  VAL B CG1 1 
ATOM   5300 C  CG2 . VAL B 1 166 ? 22.113  -10.85  12.398  1 15.049 ? 158  VAL B CG2 1 
ATOM   5301 N  N   . VAL B 1 167 ? 24.143  -13.386 10.457  1 12.827 ? 159  VAL B N   1 
ATOM   5302 C  CA  . VAL B 1 167 ? 23.753  -13.967 9.166   1 11.221 ? 159  VAL B CA  1 
ATOM   5303 C  C   . VAL B 1 167 ? 23.102  -15.33  9.403   1 11.907 ? 159  VAL B C   1 
ATOM   5304 O  O   . VAL B 1 167 ? 23.416  -15.99  10.376  1 12.272 ? 159  VAL B O   1 
ATOM   5305 C  CB  . VAL B 1 167 ? 24.926  -14.036 8.201   1 12.264 ? 159  VAL B CB  1 
ATOM   5306 C  CG1 . VAL B 1 167 ? 26.028  -15.027 8.622   1 15.597 ? 159  VAL B CG1 1 
ATOM   5307 C  CG2 . VAL B 1 167 ? 24.438  -14.189 6.726   1 13.794 ? 159  VAL B CG2 1 
ATOM   5308 N  N   . MET B 1 168 ? 22.116  -15.706 8.541   1 11.26  ? 160  MET B N   1 
ATOM   5309 C  CA  . MET B 1 168 ? 21.618  -17.089 8.542   1 11.809 ? 160  MET B CA  1 
ATOM   5310 C  C   . MET B 1 168 ? 22.146  -17.723 7.255   1 13.378 ? 160  MET B C   1 
ATOM   5311 O  O   . MET B 1 168 ? 21.77   -17.27  6.175   1 14.631 ? 160  MET B O   1 
ATOM   5312 C  CB  . MET B 1 168 ? 20.091  -17.069 8.466   1 13.456 ? 160  MET B CB  1 
ATOM   5313 C  CG  . MET B 1 168 ? 19.446  -18.496 8.425   1 14.973 ? 160  MET B CG  1 
ATOM   5314 S  SD  . MET B 1 168 ? 19.721  -19.422 9.942   1 22.687 ? 160  MET B SD  1 
ATOM   5315 C  CE  . MET B 1 168 ? 18.395  -18.661 10.884  1 19.784 ? 160  MET B CE  1 
ATOM   5316 N  N   . HIS B 1 169 ? 23.047  -18.719 7.38    1 13.879 ? 161  HIS B N   1 
ATOM   5317 C  CA  . HIS B 1 169 ? 23.645  -19.312 6.191   1 12.845 ? 161  HIS B CA  1 
ATOM   5318 C  C   . HIS B 1 169 ? 23.75   -20.809 6.418   1 15.108 ? 161  HIS B C   1 
ATOM   5319 O  O   . HIS B 1 169 ? 24.208  -21.247 7.49    1 18.759 ? 161  HIS B O   1 
ATOM   5320 C  CB  . HIS B 1 169 ? 25.071  -18.799 5.895   1 13.026 ? 161  HIS B CB  1 
ATOM   5321 C  CG  . HIS B 1 169 ? 25.571  -19.324 4.599   1 13.552 ? 161  HIS B CG  1 
ATOM   5322 N  ND1 . HIS B 1 169 ? 25.06   -18.964 3.359   1 16.092 ? 161  HIS B ND1 1 
ATOM   5323 C  CD2 . HIS B 1 169 ? 26.464  -20.307 4.383   1 14.426 ? 161  HIS B CD2 1 
ATOM   5324 C  CE1 . HIS B 1 169 ? 25.65   -19.685 2.408   1 14.692 ? 161  HIS B CE1 1 
ATOM   5325 N  NE2 . HIS B 1 169 ? 26.495  -20.501 2.97    1 13.627 ? 161  HIS B NE2 1 
ATOM   5326 N  N   . ALA B 1 170 ? 23.266  -21.553 5.408   1 18.054 ? 162  ALA B N   1 
ATOM   5327 C  CA  . ALA B 1 170 ? 23.252  -23.02  5.461   1 17.384 ? 162  ALA B CA  1 
ATOM   5328 C  C   . ALA B 1 170 ? 22.609  -23.508 6.759   1 20.395 ? 162  ALA B C   1 
ATOM   5329 O  O   . ALA B 1 170 ? 23.145  -24.402 7.441   1 21.592 ? 162  ALA B O   1 
ATOM   5330 C  CB  . ALA B 1 170 ? 24.655  -23.502 5.269   1 17.74  ? 162  ALA B CB  1 
ATOM   5331 N  N   . GLY B 1 171 ? 21.44   -22.899 7.056   1 17.253 ? 163  GLY B N   1 
ATOM   5332 C  CA  . GLY B 1 171 ? 20.596  -23.225 8.208   1 19.9   ? 163  GLY B CA  1 
ATOM   5333 C  C   . GLY B 1 171 ? 21.229  -22.94  9.56    1 17.94  ? 163  GLY B C   1 
ATOM   5334 O  O   . GLY B 1 171 ? 20.708  -23.479 10.551  1 17.181 ? 163  GLY B O   1 
ATOM   5335 N  N   . ARG B 1 172 ? 22.348  -22.186 9.55    1 17.064 ? 164  ARG B N   1 
ATOM   5336 C  CA  . ARG B 1 172 ? 23.125  -21.803 10.731  1 17.645 ? 164  ARG B CA  1 
ATOM   5337 C  C   . ARG B 1 172 ? 23.077  -20.28  10.944  1 17.348 ? 164  ARG B C   1 
ATOM   5338 O  O   . ARG B 1 172 ? 23.226  -19.491 10.012  1 13.593 ? 164  ARG B O   1 
ATOM   5339 C  CB  . ARG B 1 172 ? 24.602  -22.19  10.727  1 17.095 ? 164  ARG B CB  1 
ATOM   5340 C  CG  . ARG B 1 172 ? 24.741  -23.696 10.626  1 22.715 ? 164  ARG B CG  1 
ATOM   5341 C  CD  . ARG B 1 172 ? 26.219  -23.915 10.847  1 24.612 ? 164  ARG B CD  1 
ATOM   5342 N  NE  . ARG B 1 172 ? 26.523  -25.303 10.482  1 27.849 ? 164  ARG B NE  1 
ATOM   5343 C  CZ  . ARG B 1 172 ? 26.792  -26.265 11.313  1 29.294 ? 164  ARG B CZ  1 
ATOM   5344 N  NH1 . ARG B 1 172 ? 26.806  -26.05  12.647  1 26.624 ? 164  ARG B NH1 1 
ATOM   5345 N  NH2 . ARG B 1 172 ? 27.046  -27.455 10.779  1 34.126 ? 164  ARG B NH2 1 
ATOM   5346 N  N   . PHE B 1 173 ? 22.782  -19.902 12.205  1 15.611 ? 165  PHE B N   1 
ATOM   5347 C  CA  . PHE B 1 173 ? 22.655  -18.51  12.569  1 15.736 ? 165  PHE B CA  1 
ATOM   5348 C  C   . PHE B 1 173 ? 23.919  -18.077 13.269  1 17.307 ? 165  PHE B C   1 
ATOM   5349 O  O   . PHE B 1 173 ? 24.219  -18.64  14.331  1 14.491 ? 165  PHE B O   1 
ATOM   5350 C  CB  . PHE B 1 173 ? 21.415  -18.276 13.46   1 15.86  ? 165  PHE B CB  1 
ATOM   5351 C  CG  . PHE B 1 173 ? 21.23   -16.819 13.858  1 12.643 ? 165  PHE B CG  1 
ATOM   5352 C  CD1 . PHE B 1 173 ? 20.893  -15.895 12.878  1 13.663 ? 165  PHE B CD1 1 
ATOM   5353 C  CD2 . PHE B 1 173 ? 21.43   -16.39  15.185  1 13.212 ? 165  PHE B CD2 1 
ATOM   5354 C  CE1 . PHE B 1 173 ? 20.763  -14.555 13.197  1 16.73  ? 165  PHE B CE1 1 
ATOM   5355 C  CE2 . PHE B 1 173 ? 21.26   -15.025 15.51   1 16.468 ? 165  PHE B CE2 1 
ATOM   5356 C  CZ  . PHE B 1 173 ? 20.935  -14.108 14.51   1 15.048 ? 165  PHE B CZ  1 
ATOM   5357 N  N   . LEU B 1 174 ? 24.561  -17.016 12.738  1 15.49  ? 166  LEU B N   1 
ATOM   5358 C  CA  . LEU B 1 174 ? 25.926  -16.66  13.159  1 14.857 ? 166  LEU B CA  1 
ATOM   5359 C  C   . LEU B 1 174 ? 25.985  -15.226 13.635  1 13.649 ? 166  LEU B C   1 
ATOM   5360 O  O   . LEU B 1 174 ? 25.404  -14.377 12.964  1 13.149 ? 166  LEU B O   1 
ATOM   5361 C  CB  . LEU B 1 174 ? 26.99   -16.792 12.046  1 12.578 ? 166  LEU B CB  1 
ATOM   5362 C  CG  . LEU B 1 174 ? 27.536  -18.171 11.665  1 16.279 ? 166  LEU B CG  1 
ATOM   5363 C  CD1 . LEU B 1 174 ? 26.649  -19.347 11.762  1 16.074 ? 166  LEU B CD1 1 
ATOM   5364 C  CD2 . LEU B 1 174 ? 28.017  -18.053 10.216  1 14.892 ? 166  LEU B CD2 1 
ATOM   5365 N  N   . ALA B 1 175 ? 26.625  -15.015 14.81   1 14.198 ? 167  ALA B N   1 
ATOM   5366 C  CA  . ALA B 1 175 ? 27.117  -13.729 15.292  1 14.176 ? 167  ALA B CA  1 
ATOM   5367 C  C   . ALA B 1 175 ? 28.627  -13.581 14.976  1 13.564 ? 167  ALA B C   1 
ATOM   5368 O  O   . ALA B 1 175 ? 29.434  -14.491 15.24   1 16.601 ? 167  ALA B O   1 
ATOM   5369 C  CB  . ALA B 1 175 ? 26.96   -13.707 16.836  1 16.867 ? 167  ALA B CB  1 
ATOM   5370 N  N   . MET B 1 176 ? 29.011  -12.42  14.435  1 12.661 ? 168  MET B N   1 
ATOM   5371 C  CA  . MET B 1 176 ? 30.284  -12.145 13.771  1 11.486 ? 168  MET B CA  1 
ATOM   5372 C  C   . MET B 1 176 ? 30.973  -10.887 14.312  1 11.321 ? 168  MET B C   1 
ATOM   5373 O  O   . MET B 1 176 ? 30.383  -9.893  14.673  1 13.106 ? 168  MET B O   1 
ATOM   5374 C  CB  . MET B 1 176 ? 30.021  -11.932 12.269  1 11.293 ? 168  MET B CB  1 
ATOM   5375 C  CG  . MET B 1 176 ? 29.445  -13.143 11.622  1 11.546 ? 168  MET B CG  1 
ATOM   5376 S  SD  . MET B 1 176 ? 29.152  -12.961 9.838   1 15.366 ? 168  MET B SD  1 
ATOM   5377 C  CE  . MET B 1 176 ? 27.685  -11.887 9.818   1 11.738 ? 168  MET B CE  1 
ATOM   5378 N  N   . LYS B 1 177 ? 32.28   -10.983 14.444  1 11.679 ? 169  LYS B N   1 
ATOM   5379 C  CA  . LYS B 1 177 ? 33.181  -9.861  14.664  1 14.825 ? 169  LYS B CA  1 
ATOM   5380 C  C   . LYS B 1 177 ? 34.494  -10.247 13.969  1 14.073 ? 169  LYS B C   1 
ATOM   5381 O  O   . LYS B 1 177 ? 34.971  -11.373 14.112  1 14.797 ? 169  LYS B O   1 
ATOM   5382 C  CB  . LYS B 1 177 ? 33.369  -9.615  16.182  1 11.229 ? 169  LYS B CB  1 
ATOM   5383 C  CG  . LYS B 1 177 ? 33.965  -8.205  16.423  1 13.636 ? 169  LYS B CG  1 
ATOM   5384 C  CD  . LYS B 1 177 ? 34.335  -8.037  17.915  1 13.344 ? 169  LYS B CD  1 
ATOM   5385 C  CE  . LYS B 1 177 ? 34.911  -6.637  18.182  1 13.64  ? 169  LYS B CE  1 
ATOM   5386 N  NZ  . LYS B 1 177 ? 33.926  -5.584  17.775  1 12.269 ? 169  LYS B NZ  1 
ATOM   5387 N  N   . GLU B 1 178 ? 35.121  -9.275  13.29   1 13.854 ? 170  GLU B N   1 
ATOM   5388 C  CA  . GLU B 1 178 ? 36.156  -9.533  12.294  1 12.943 ? 170  GLU B CA  1 
ATOM   5389 C  C   . GLU B 1 178 ? 37.469  -10.013 12.9    1 13.34  ? 170  GLU B C   1 
ATOM   5390 O  O   . GLU B 1 178 ? 38.36   -10.349 12.122  1 14.162 ? 170  GLU B O   1 
ATOM   5391 C  CB  . GLU B 1 178 ? 36.319  -8.324  11.372  1 13.647 ? 170  GLU B CB  1 
ATOM   5392 C  CG  . GLU B 1 178 ? 37.049  -7.16   12.018  1 12.344 ? 170  GLU B CG  1 
ATOM   5393 C  CD  . GLU B 1 178 ? 36.606  -5.846  11.41   1 13.148 ? 170  GLU B CD  1 
ATOM   5394 O  OE1 . GLU B 1 178 ? 35.392  -5.464  11.451  1 13.063 ? 170  GLU B OE1 1 
ATOM   5395 O  OE2 . GLU B 1 178 ? 37.542  -5.31   10.801  1 13.184 ? 170  GLU B OE2 1 
ATOM   5396 N  N   . ASN B 1 179 ? 37.622  -9.96   14.255  1 12.895 ? 171  ASN B N   1 
ATOM   5397 C  CA  . ASN B 1 179 ? 38.843  -10.41  14.91   1 12.978 ? 171  ASN B CA  1 
ATOM   5398 C  C   . ASN B 1 179 ? 38.791  -11.915 15.265  1 13.91  ? 171  ASN B C   1 
ATOM   5399 O  O   . ASN B 1 179 ? 39.695  -12.419 15.964  1 16.368 ? 171  ASN B O   1 
ATOM   5400 C  CB  . ASN B 1 179 ? 39.249  -9.543  16.123  1 13.233 ? 171  ASN B CB  1 
ATOM   5401 C  CG  . ASN B 1 179 ? 38.206  -9.53   17.199  1 15.327 ? 171  ASN B CG  1 
ATOM   5402 O  OD1 . ASN B 1 179 ? 37.034  -9.78   16.902  1 12.654 ? 171  ASN B OD1 1 
ATOM   5403 N  ND2 . ASN B 1 179 ? 38.664  -9.326  18.44   1 14.427 ? 171  ASN B ND2 1 
ATOM   5404 N  N   . GLY B 1 180 ? 37.68   -12.607 14.886  1 13.693 ? 172  GLY B N   1 
ATOM   5405 C  CA  . GLY B 1 180 ? 37.653  -14.067 15.052  1 12.093 ? 172  GLY B CA  1 
ATOM   5406 C  C   . GLY B 1 180 ? 36.695  -14.708 14.038  1 14.179 ? 172  GLY B C   1 
ATOM   5407 O  O   . GLY B 1 180 ? 36.014  -14.036 13.3    1 13.251 ? 172  GLY B O   1 
ATOM   5408 N  N   . ASN B 1 181 ? 36.586  -16.033 14.085  1 15.335 ? 173  ASN B N   1 
ATOM   5409 C  CA  . ASN B 1 181 ? 35.501  -16.733 13.423  1 15.219 ? 173  ASN B CA  1 
ATOM   5410 C  C   . ASN B 1 181 ? 34.203  -16.452 14.151  1 16.215 ? 173  ASN B C   1 
ATOM   5411 O  O   . ASN B 1 181 ? 34.185  -15.982 15.311  1 12.526 ? 173  ASN B O   1 
ATOM   5412 C  CB  . ASN B 1 181 ? 35.864  -18.207 13.262  1 14.293 ? 173  ASN B CB  1 
ATOM   5413 C  CG  . ASN B 1 181 ? 36.745  -18.39  12.047  1 14.729 ? 173  ASN B CG  1 
ATOM   5414 O  OD1 . ASN B 1 181 ? 36.303  -18.161 10.891  1 13.938 ? 173  ASN B OD1 1 
ATOM   5415 N  ND2 . ASN B 1 181 ? 38.001  -18.741 12.309  1 16.378 ? 173  ASN B ND2 1 
ATOM   5416 N  N   . ALA B 1 182 ? 33.13   -16.924 13.51   1 13.902 ? 174  ALA B N   1 
ATOM   5417 C  CA  . ALA B 1 182 ? 31.797  -16.668 14.02   1 15.136 ? 174  ALA B CA  1 
ATOM   5418 C  C   . ALA B 1 182 ? 31.464  -17.611 15.17   1 15.797 ? 174  ALA B C   1 
ATOM   5419 O  O   . ALA B 1 182 ? 32.07   -18.701 15.287  1 14.775 ? 174  ALA B O   1 
ATOM   5420 C  CB  . ALA B 1 182 ? 30.814  -16.848 12.875  1 12.459 ? 174  ALA B CB  1 
ATOM   5421 N  N   . TYR B 1 183 ? 30.547  -17.151 16.022  1 13.481 ? 175  TYR B N   1 
ATOM   5422 C  CA  . TYR B 1 183 ? 29.852  -18.048 16.929  1 15.457 ? 175  TYR B CA  1 
ATOM   5423 C  C   . TYR B 1 183 ? 28.437  -18.321 16.396  1 15.055 ? 175  TYR B C   1 
ATOM   5424 O  O   . TYR B 1 183 ? 27.711  -17.411 16.056  1 16.288 ? 175  TYR B O   1 
ATOM   5425 C  CB  . TYR B 1 183 ? 29.823  -17.399 18.315  1 14.19  ? 175  TYR B CB  1 
ATOM   5426 C  CG  . TYR B 1 183 ? 31.157  -17.277 19.051  1 14.137 ? 175  TYR B CG  1 
ATOM   5427 C  CD1 . TYR B 1 183 ? 32.041  -16.212 18.832  1 15.204 ? 175  TYR B CD1 1 
ATOM   5428 C  CD2 . TYR B 1 183 ? 31.49   -18.236 19.998  1 14.466 ? 175  TYR B CD2 1 
ATOM   5429 C  CE1 . TYR B 1 183 ? 33.212  -16.088 19.593  1 13.075 ? 175  TYR B CE1 1 
ATOM   5430 C  CE2 . TYR B 1 183 ? 32.67   -18.194 20.714  1 13.75  ? 175  TYR B CE2 1 
ATOM   5431 C  CZ  . TYR B 1 183 ? 33.526  -17.102 20.505  1 14.313 ? 175  TYR B CZ  1 
ATOM   5432 O  OH  . TYR B 1 183 ? 34.62   -17.101 21.313  1 13.781 ? 175  TYR B OH  1 
ATOM   5433 N  N   . GLU B 1 184 ? 28.005  -19.591 16.384  1 16.992 ? 176  GLU B N   1 
ATOM   5434 C  CA  . GLU B 1 184 ? 26.654  -19.985 16.057  1 14.362 ? 176  GLU B CA  1 
ATOM   5435 C  C   . GLU B 1 184 ? 25.772  -19.901 17.305  1 17.991 ? 176  GLU B C   1 
ATOM   5436 O  O   . GLU B 1 184 ? 26.208  -20.201 18.432  1 16.685 ? 176  GLU B O   1 
ATOM   5437 C  CB  . GLU B 1 184 ? 26.678  -21.432 15.566  1 14.404 ? 176  GLU B CB  1 
ATOM   5438 C  CG  . GLU B 1 184 ? 25.317  -21.91  15.056  1 16.275 ? 176  GLU B CG  1 
ATOM   5439 C  CD  . GLU B 1 184 ? 25.271  -23.276 14.374  1 17.784 ? 176  GLU B CD  1 
ATOM   5440 O  OE1 . GLU B 1 184 ? 26.347  -23.876 14.231  1 20.081 ? 176  GLU B OE1 1 
ATOM   5441 O  OE2 . GLU B 1 184 ? 24.149  -23.689 14      1 17.143 ? 176  GLU B OE2 1 
ATOM   5442 N  N   . MET B 1 185 ? 24.506  -19.497 17.068  1 16.11  ? 177  MET B N   1 
ATOM   5443 C  CA  . MET B 1 185 ? 23.499  -19.491 18.108  1 16.854 ? 177  MET B CA  1 
ATOM   5444 C  C   . MET B 1 185 ? 22.273  -20.198 17.562  1 14.658 ? 177  MET B C   1 
ATOM   5445 O  O   . MET B 1 185 ? 22.018  -20.182 16.364  1 15.042 ? 177  MET B O   1 
ATOM   5446 C  CB  . MET B 1 185 ? 23.091  -18.037 18.353  1 14.001 ? 177  MET B CB  1 
ATOM   5447 C  CG  . MET B 1 185 ? 24.214  -17.2   18.87   1 14.608 ? 177  MET B CG  1 
ATOM   5448 S  SD  . MET B 1 185 ? 23.896  -15.426 18.878  1 17.94  ? 177  MET B SD  1 
ATOM   5449 C  CE  . MET B 1 185 ? 23.361  -15.183 20.589  1 14.848 ? 177  MET B CE  1 
ATOM   5450 N  N   . ASP B 1 186 ? 21.479  -20.753 18.466  1 16.118 ? 178  ASP B N   1 
ATOM   5451 C  CA  . ASP B 1 186 ? 20.171  -21.258 18.087  1 17.939 ? 178  ASP B CA  1 
ATOM   5452 C  C   . ASP B 1 186 ? 19.3    -20.078 17.65   1 17.178 ? 178  ASP B C   1 
ATOM   5453 O  O   . ASP B 1 186 ? 19.251  -19.09  18.373  1 15.029 ? 178  ASP B O   1 
ATOM   5454 C  CB  . ASP B 1 186 ? 19.523  -22.026 19.24   1 17.714 ? 178  ASP B CB  1 
ATOM   5455 C  CG  . ASP B 1 186 ? 18.186  -22.646 18.867  1 19.895 ? 178  ASP B CG  1 
ATOM   5456 O  OD1 . ASP B 1 186 ? 17.16   -21.915 18.81   1 15.363 ? 178  ASP B OD1 1 
ATOM   5457 O  OD2 . ASP B 1 186 ? 18.199  -23.851 18.561  1 21.023 ? 178  ASP B OD2 1 
ATOM   5458 N  N   . PRO B 1 187 ? 18.588  -20.097 16.488  1 16.872 ? 179  PRO B N   1 
ATOM   5459 C  CA  . PRO B 1 187 ? 17.799  -18.938 16.063  1 16.928 ? 179  PRO B CA  1 
ATOM   5460 C  C   . PRO B 1 187 ? 16.485  -18.662 16.807  1 19.084 ? 179  PRO B C   1 
ATOM   5461 O  O   . PRO B 1 187 ? 15.897  -17.564 16.62   1 17.628 ? 179  PRO B O   1 
ATOM   5462 C  CB  . PRO B 1 187 ? 17.551  -19.218 14.569  1 16.167 ? 179  PRO B CB  1 
ATOM   5463 C  CG  . PRO B 1 187 ? 17.372  -20.709 14.546  1 15.787 ? 179  PRO B CG  1 
ATOM   5464 C  CD  . PRO B 1 187 ? 18.494  -21.187 15.496  1 18.614 ? 179  PRO B CD  1 
ATOM   5465 N  N   . HIS B 1 188 ? 16.084  -19.579 17.732  1 16.768 ? 180  HIS B N   1 
ATOM   5466 C  CA  . HIS B 1 188 ? 14.842  -19.379 18.451  1 15.695 ? 180  HIS B CA  1 
ATOM   5467 C  C   . HIS B 1 188 ? 15.157  -19.01  19.923  1 16.06  ? 180  HIS B C   1 
ATOM   5468 O  O   . HIS B 1 188 ? 14.519  -18.124 20.457  1 16.014 ? 180  HIS B O   1 
ATOM   5469 C  CB  . HIS B 1 188 ? 13.934  -20.628 18.32   1 15.169 ? 180  HIS B CB  1 
ATOM   5470 C  CG  . HIS B 1 188 ? 13.844  -21.15  16.9    1 15.454 ? 180  HIS B CG  1 
ATOM   5471 N  ND1 . HIS B 1 188 ? 13.194  -20.543 15.851  1 15.121 ? 180  HIS B ND1 1 
ATOM   5472 C  CD2 . HIS B 1 188 ? 14.386  -22.271 16.37   1 18.416 ? 180  HIS B CD2 1 
ATOM   5473 C  CE1 . HIS B 1 188 ? 13.306  -21.251 14.709  1 13.955 ? 180  HIS B CE1 1 
ATOM   5474 N  NE2 . HIS B 1 188 ? 14.044  -22.332 14.982  1 17.085 ? 180  HIS B NE2 1 
ATOM   5475 N  N   . THR B 1 189 ? 16.097  -19.734 20.562  1 13.111 ? 181  THR B N   1 
ATOM   5476 C  CA  . THR B 1 189 ? 16.404  -19.569 21.985  1 13.323 ? 181  THR B CA  1 
ATOM   5477 C  C   . THR B 1 189 ? 17.588  -18.607 22.133  1 13.513 ? 181  THR B C   1 
ATOM   5478 O  O   . THR B 1 189 ? 17.799  -18.093 23.244  1 12.991 ? 181  THR B O   1 
ATOM   5479 C  CB  . THR B 1 189 ? 16.69   -20.883 22.695  1 18.472 ? 181  THR B CB  1 
ATOM   5480 O  OG1 . THR B 1 189 ? 17.908  -21.37  22.133  1 18.169 ? 181  THR B OG1 1 
ATOM   5481 C  CG2 . THR B 1 189 ? 15.551  -21.892 22.558  1 19.45  ? 181  THR B CG2 1 
ATOM   5482 N  N   . LEU B 1 190 ? 18.316  -18.364 21.024  1 13.683 ? 182  LEU B N   1 
ATOM   5483 C  CA  . LEU B 1 190 ? 19.618  -17.65  21.029  1 13.842 ? 182  LEU B CA  1 
ATOM   5484 C  C   . LEU B 1 190 ? 20.695  -18.309 21.895  1 13.364 ? 182  LEU B C   1 
ATOM   5485 O  O   . LEU B 1 190 ? 21.748  -17.698 22.118  1 13.731 ? 182  LEU B O   1 
ATOM   5486 C  CB  . LEU B 1 190 ? 19.511  -16.124 21.271  1 13.948 ? 182  LEU B CB  1 
ATOM   5487 C  CG  . LEU B 1 190 ? 18.614  -15.414 20.264  1 16.951 ? 182  LEU B CG  1 
ATOM   5488 C  CD1 . LEU B 1 190 ? 18.504  -13.979 20.718  1 14.188 ? 182  LEU B CD1 1 
ATOM   5489 C  CD2 . LEU B 1 190 ? 19.325  -15.536 18.844  1 12.462 ? 182  LEU B CD2 1 
ATOM   5490 N  N   . LYS B 1 191 ? 20.523  -19.588 22.252  1 15.316 ? 183  LYS B N   1 
ATOM   5491 C  CA  . LYS B 1 191 ? 21.589  -20.345 22.93   1 18.198 ? 183  LYS B CA  1 
ATOM   5492 C  C   . LYS B 1 191 ? 22.811  -20.421 22.024  1 17.414 ? 183  LYS B C   1 
ATOM   5493 O  O   . LYS B 1 191 ? 22.651  -20.625 20.796  1 18.825 ? 183  LYS B O   1 
ATOM   5494 C  CB  . LYS B 1 191 ? 21.095  -21.76  23.276  1 20.726 ? 183  LYS B CB  1 
ATOM   5495 C  CG  . LYS B 1 191 ? 22.163  -22.605 23.94   1 26.113 ? 183  LYS B CG  1 
ATOM   5496 C  CD  . LYS B 1 191 ? 21.637  -23.719 24.838  1 31.14  ? 183  LYS B CD  1 
ATOM   5497 C  CE  . LYS B 1 191 ? 22.771  -24.451 25.5    1 24.739 ? 183  LYS B CE  1 
ATOM   5498 N  NZ  . LYS B 1 191 ? 22.976  -23.8   26.786  1 25.799 ? 183  LYS B NZ  1 
ATOM   5499 N  N   . THR B 1 192 ? 24.01   -20.182 22.616  1 15.141 ? 184  THR B N   1 
ATOM   5500 C  CA  . THR B 1 192 ? 25.231  -20.404 21.824  1 14.642 ? 184  THR B CA  1 
ATOM   5501 C  C   . THR B 1 192 ? 25.51   -21.906 21.648  1 14.114 ? 184  THR B C   1 
ATOM   5502 O  O   . THR B 1 192 ? 25.403  -22.671 22.62   1 14.901 ? 184  THR B O   1 
ATOM   5503 C  CB  . THR B 1 192 ? 26.397  -19.658 22.452  1 13.56  ? 184  THR B CB  1 
ATOM   5504 O  OG1 . THR B 1 192 ? 26.03   -18.288 22.358  1 15.613 ? 184  THR B OG1 1 
ATOM   5505 C  CG2 . THR B 1 192 ? 27.764  -19.886 21.806  1 13.352 ? 184  THR B CG2 1 
ATOM   5506 N  N   . LEU B 1 193 ? 25.754  -22.275 20.385  1 12.823 ? 185  LEU B N   1 
ATOM   5507 C  CA  . LEU B 1 193 ? 25.992  -23.665 19.974  1 16.826 ? 185  LEU B CA  1 
ATOM   5508 C  C   . LEU B 1 193 ? 27.451  -24.024 19.703  1 16.235 ? 185  LEU B C   1 
ATOM   5509 O  O   . LEU B 1 193 ? 27.793  -25.212 19.748  1 19.358 ? 185  LEU B O   1 
ATOM   5510 C  CB  . LEU B 1 193 ? 25.159  -23.842 18.714  1 15.635 ? 185  LEU B CB  1 
ATOM   5511 C  CG  . LEU B 1 193 ? 23.667  -23.587 18.957  1 15.069 ? 185  LEU B CG  1 
ATOM   5512 C  CD1 . LEU B 1 193 ? 23.028  -23.938 17.643  1 14.912 ? 185  LEU B CD1 1 
ATOM   5513 C  CD2 . LEU B 1 193 ? 23.027  -24.36  20.177  1 15.569 ? 185  LEU B CD2 1 
ATOM   5514 N  N   . GLY B 1 194 ? 28.309  -23.035 19.379  1 14.715 ? 186  GLY B N   1 
ATOM   5515 C  CA  . GLY B 1 194 ? 29.704  -23.378 19.064  1 16.833 ? 186  GLY B CA  1 
ATOM   5516 C  C   . GLY B 1 194 ? 30.424  -22.225 18.381  1 20.127 ? 186  GLY B C   1 
ATOM   5517 O  O   . GLY B 1 194 ? 29.824  -21.142 18.247  1 20.483 ? 186  GLY B O   1 
ATOM   5518 N  N   . TYR B 1 195 ? 31.676  -22.498 17.954  1 19.151 ? 187  TYR B N   1 
ATOM   5519 C  CA  . TYR B 1 195 ? 32.57   -21.516 17.351  1 13.864 ? 187  TYR B CA  1 
ATOM   5520 C  C   . TYR B 1 195 ? 33.057  -22.085 16.036  1 14.309 ? 187  TYR B C   1 
ATOM   5521 O  O   . TYR B 1 195 ? 33.351  -23.281 15.948  1 14.937 ? 187  TYR B O   1 
ATOM   5522 C  CB  . TYR B 1 195 ? 33.741  -21.247 18.304  1 14.11  ? 187  TYR B CB  1 
ATOM   5523 C  CG  . TYR B 1 195 ? 34.852  -20.375 17.725  1 14.646 ? 187  TYR B CG  1 
ATOM   5524 C  CD1 . TYR B 1 195 ? 34.714  -18.985 17.648  1 14.718 ? 187  TYR B CD1 1 
ATOM   5525 C  CD2 . TYR B 1 195 ? 35.992  -20.959 17.191  1 14.332 ? 187  TYR B CD2 1 
ATOM   5526 C  CE1 . TYR B 1 195 ? 35.715  -18.191 17.088  1 14.234 ? 187  TYR B CE1 1 
ATOM   5527 C  CE2 . TYR B 1 195 ? 37.038  -20.158 16.693  1 12.669 ? 187  TYR B CE2 1 
ATOM   5528 C  CZ  . TYR B 1 195 ? 36.881  -18.776 16.623  1 15.136 ? 187  TYR B CZ  1 
ATOM   5529 O  OH  . TYR B 1 195 ? 37.883  -17.986 16.12   1 15.976 ? 187  TYR B OH  1 
ATOM   5530 N  N   . ASN B 1 196 ? 33.118  -21.209 15.02   1 13.303 ? 188  ASN B N   1 
ATOM   5531 C  CA  . ASN B 1 196 ? 33.612  -21.526 13.679  1 13.851 ? 188  ASN B CA  1 
ATOM   5532 C  C   . ASN B 1 196 ? 32.939  -22.768 13.12   1 14.794 ? 188  ASN B C   1 
ATOM   5533 O  O   . ASN B 1 196 ? 33.614  -23.794 12.81   1 15.134 ? 188  ASN B O   1 
ATOM   5534 C  CB  . ASN B 1 196 ? 35.138  -21.712 13.754  1 12.001 ? 188  ASN B CB  1 
ATOM   5535 C  CG  . ASN B 1 196 ? 35.806  -21.773 12.391  1 15.76  ? 188  ASN B CG  1 
ATOM   5536 O  OD1 . ASN B 1 196 ? 35.272  -21.294 11.397  1 16.65  ? 188  ASN B OD1 1 
ATOM   5537 N  ND2 . ASN B 1 196 ? 36.995  -22.351 12.344  1 16.722 ? 188  ASN B ND2 1 
ATOM   5538 N  N   . PRO B 1 197 ? 31.614  -22.678 12.871  1 15.624 ? 189  PRO B N   1 
ATOM   5539 C  CA  . PRO B 1 197 ? 30.845  -23.817 12.387  1 17.724 ? 189  PRO B CA  1 
ATOM   5540 C  C   . PRO B 1 197 ? 31.215  -24.309 10.996  1 23.498 ? 189  PRO B C   1 
ATOM   5541 O  O   . PRO B 1 197 ? 31.052  -25.491 10.704  1 20.095 ? 189  PRO B O   1 
ATOM   5542 C  CB  . PRO B 1 197 ? 29.412  -23.273 12.361  1 16.218 ? 189  PRO B CB  1 
ATOM   5543 C  CG  . PRO B 1 197 ? 29.573  -21.782 12.23   1 16.528 ? 189  PRO B CG  1 
ATOM   5544 C  CD  . PRO B 1 197 ? 30.745  -21.504 13.132  1 13.132 ? 189  PRO B CD  1 
ATOM   5545 N  N   . PHE B 1 198 ? 31.695  -23.402 10.139  1 18.697 ? 190  PHE B N   1 
ATOM   5546 C  CA  . PHE B 1 198 ? 32.158  -23.823 8.817   1 18.562 ? 190  PHE B CA  1 
ATOM   5547 C  C   . PHE B 1 198 ? 33.659  -24.207 8.81    1 16.557 ? 190  PHE B C   1 
ATOM   5548 O  O   . PHE B 1 198 ? 34.227  -24.511 7.763   1 15.489 ? 190  PHE B O   1 
ATOM   5549 C  CB  . PHE B 1 198 ? 31.86   -22.664 7.873   1 19.243 ? 190  PHE B CB  1 
ATOM   5550 C  CG  . PHE B 1 198 ? 30.414  -22.25  7.77    1 18.622 ? 190  PHE B CG  1 
ATOM   5551 C  CD1 . PHE B 1 198 ? 29.361  -23.187 7.695   1 18.669 ? 190  PHE B CD1 1 
ATOM   5552 C  CD2 . PHE B 1 198 ? 30.109  -20.91  7.906   1 20.122 ? 190  PHE B CD2 1 
ATOM   5553 C  CE1 . PHE B 1 198 ? 28.053  -22.753 7.634   1 22.781 ? 190  PHE B CE1 1 
ATOM   5554 C  CE2 . PHE B 1 198 ? 28.799  -20.477 7.833   1 20.26  ? 190  PHE B CE2 1 
ATOM   5555 C  CZ  . PHE B 1 198 ? 27.773  -21.385 7.756   1 20.073 ? 190  PHE B CZ  1 
ATOM   5556 N  N   . ASN B 1 199 ? 34.306  -24.275 9.982   1 13.593 ? 191  ASN B N   1 
ATOM   5557 C  CA  . ASN B 1 199 ? 35.673  -24.793 10.055  1 15.417 ? 191  ASN B CA  1 
ATOM   5558 C  C   . ASN B 1 199 ? 36.665  -24.099 9.12    1 18.171 ? 191  ASN B C   1 
ATOM   5559 O  O   . ASN B 1 199 ? 37.519  -24.775 8.515   1 14.157 ? 191  ASN B O   1 
ATOM   5560 C  CB  . ASN B 1 199 ? 35.784  -26.327 9.867   1 19.873 ? 191  ASN B CB  1 
ATOM   5561 C  CG  . ASN B 1 199 ? 35.18   -27.078 11.029  1 26.736 ? 191  ASN B CG  1 
ATOM   5562 O  OD1 . ASN B 1 199 ? 34.278  -27.912 10.85   1 35.422 ? 191  ASN B OD1 1 
ATOM   5563 N  ND2 . ASN B 1 199 ? 35.659  -26.774 12.228  1 22.973 ? 191  ASN B ND2 1 
ATOM   5564 N  N   . LEU B 1 200 ? 36.557  -22.744 9.024   1 15.322 ? 192  LEU B N   1 
ATOM   5565 C  CA  . LEU B 1 200 ? 37.495  -21.939 8.269   1 15.884 ? 192  LEU B CA  1 
ATOM   5566 C  C   . LEU B 1 200 ? 38.904  -22.056 8.841   1 19.179 ? 192  LEU B C   1 
ATOM   5567 O  O   . LEU B 1 200 ? 39.122  -22.051 10.073  1 18.273 ? 192  LEU B O   1 
ATOM   5568 C  CB  . LEU B 1 200 ? 37.03   -20.48  8.151   1 17.08  ? 192  LEU B CB  1 
ATOM   5569 C  CG  . LEU B 1 200 ? 35.602  -20.235 7.677   1 15.217 ? 192  LEU B CG  1 
ATOM   5570 C  CD1 . LEU B 1 200 ? 35.631  -18.703 7.574   1 17.811 ? 192  LEU B CD1 1 
ATOM   5571 C  CD2 . LEU B 1 200 ? 35.23   -20.807 6.341   1 16.241 ? 192  LEU B CD2 1 
ATOM   5572 N  N   . PRO B 1 201 ? 39.906  -22.19  7.948   1 19.638 ? 193  PRO B N   1 
ATOM   5573 C  CA  . PRO B 1 201 ? 41.304  -22.274 8.382   1 19.688 ? 193  PRO B CA  1 
ATOM   5574 C  C   . PRO B 1 201 ? 41.912  -20.954 8.862   1 19.736 ? 193  PRO B C   1 
ATOM   5575 O  O   . PRO B 1 201 ? 42.998  -20.937 9.481   1 16.976 ? 193  PRO B O   1 
ATOM   5576 C  CB  . PRO B 1 201 ? 42.072  -22.82  7.129   1 20.348 ? 193  PRO B CB  1 
ATOM   5577 C  CG  . PRO B 1 201 ? 41.142  -22.374 6.002   1 22.356 ? 193  PRO B CG  1 
ATOM   5578 C  CD  . PRO B 1 201 ? 39.721  -22.408 6.492   1 17.699 ? 193  PRO B CD  1 
ATOM   5579 N  N   . SER B 1 202 ? 41.219  -19.847 8.572   1 16.896 ? 194  SER B N   1 
ATOM   5580 C  CA  . SER B 1 202 ? 41.709  -18.546 9.023   1 16.882 ? 194  SER B CA  1 
ATOM   5581 C  C   . SER B 1 202 ? 41.407  -18.385 10.529  1 16.301 ? 194  SER B C   1 
ATOM   5582 O  O   . SER B 1 202 ? 40.585  -19.148 11.087  1 14.76  ? 194  SER B O   1 
ATOM   5583 C  CB  . SER B 1 202 ? 41.109  -17.465 8.206   1 18.441 ? 194  SER B CB  1 
ATOM   5584 O  OG  . SER B 1 202 ? 39.719  -17.7   8.16    1 25.258 ? 194  SER B OG  1 
ATOM   5585 N  N   . LYS B 1 203 ? 42.231  -17.567 11.232  1 15.657 ? 195  LYS B N   1 
ATOM   5586 C  CA  . LYS B 1 203 ? 41.922  -17.232 12.627  1 13.627 ? 195  LYS B CA  1 
ATOM   5587 C  C   . LYS B 1 203 ? 40.715  -16.276 12.697  1 11.984 ? 195  LYS B C   1 
ATOM   5588 O  O   . LYS B 1 203 ? 40.213  -16.029 13.823  1 11.337 ? 195  LYS B O   1 
ATOM   5589 C  CB  . LYS B 1 203 ? 43.106  -16.671 13.439  1 15.378 ? 195  LYS B CB  1 
ATOM   5590 C  CG  . LYS B 1 203 ? 44.385  -17.475 13.428  1 15.704 ? 195  LYS B CG  1 
ATOM   5591 C  CD  . LYS B 1 203 ? 45.397  -16.882 14.42   1 16.938 ? 195  LYS B CD  1 
ATOM   5592 C  CE  . LYS B 1 203 ? 46.588  -17.794 14.352  1 20.961 ? 195  LYS B CE  1 
ATOM   5593 N  NZ  . LYS B 1 203 ? 46.707  -18.564 15.584  1 25.466 ? 195  LYS B NZ  1 
ATOM   5594 N  N   . THR B 1 204 ? 40.305  -15.72  11.51   1 11.676 ? 196  THR B N   1 
ATOM   5595 C  CA  . THR B 1 204 ? 39.31   -14.65  11.514  1 12.845 ? 196  THR B CA  1 
ATOM   5596 C  C   . THR B 1 204 ? 38.286  -14.837 10.401  1 14.344 ? 196  THR B C   1 
ATOM   5597 O  O   . THR B 1 204 ? 38.556  -15.502 9.406   1 14.626 ? 196  THR B O   1 
ATOM   5598 C  CB  . THR B 1 204 ? 40.011  -13.294 11.324  1 11.435 ? 196  THR B CB  1 
ATOM   5599 O  OG1 . THR B 1 204 ? 40.66   -13.371 10.056  1 13.132 ? 196  THR B OG1 1 
ATOM   5600 C  CG2 . THR B 1 204 ? 40.983  -12.953 12.451  1 12.687 ? 196  THR B CG2 1 
ATOM   5601 N  N   . MET B 1 205 ? 37.128  -14.194 10.563  1 15.467 ? 197  MET B N   1 
ATOM   5602 C  CA  . MET B 1 205 ? 36.171  -14.072 9.476   1 15.41  ? 197  MET B CA  1 
ATOM   5603 C  C   . MET B 1 205 ? 35.594  -12.665 9.564   1 16.258 ? 197  MET B C   1 
ATOM   5604 O  O   . MET B 1 205 ? 35.237  -12.205 10.652  1 14.919 ? 197  MET B O   1 
ATOM   5605 C  CB  . MET B 1 205 ? 35.037  -15.106 9.542   1 13.335 ? 197  MET B CB  1 
ATOM   5606 C  CG  . MET B 1 205 ? 34.18   -15.048 8.299   1 13.495 ? 197  MET B CG  1 
ATOM   5607 S  SD  . MET B 1 205 ? 32.745  -16.12  8.395   1 14.625 ? 197  MET B SD  1 
ATOM   5608 C  CE  . MET B 1 205 ? 31.472  -15.19  9.265   1 14.621 ? 197  MET B CE  1 
ATOM   5609 N  N   . THR B 1 206 ? 35.521  -12     8.396   1 14.444 ? 198  THR B N   1 
ATOM   5610 C  CA  . THR B 1 206 ? 34.852  -10.704 8.33    1 12.431 ? 198  THR B CA  1 
ATOM   5611 C  C   . THR B 1 206 ? 33.454  -10.804 8.973   1 13.077 ? 198  THR B C   1 
ATOM   5612 O  O   . THR B 1 206 ? 32.785  -11.868 8.936   1 12.177 ? 198  THR B O   1 
ATOM   5613 C  CB  . THR B 1 206 ? 34.759  -10.32  6.828   1 13.111 ? 198  THR B CB  1 
ATOM   5614 O  OG1 . THR B 1 206 ? 34.127  -9.031  6.725   1 13.365 ? 198  THR B OG1 1 
ATOM   5615 C  CG2 . THR B 1 206 ? 33.77   -11.182 6.049   1 13.609 ? 198  THR B CG2 1 
ATOM   5616 N  N   . ALA B 1 207 ? 32.944  -9.654  9.452   1 10.333 ? 199  ALA B N   1 
ATOM   5617 C  CA  . ALA B 1 207 ? 31.541  -9.546  9.85    1 11.769 ? 199  ALA B CA  1 
ATOM   5618 C  C   . ALA B 1 207 ? 30.708  -9.088  8.689   1 12.132 ? 199  ALA B C   1 
ATOM   5619 O  O   . ALA B 1 207 ? 29.499  -8.927  8.866   1 15.689 ? 199  ALA B O   1 
ATOM   5620 C  CB  . ALA B 1 207 ? 31.33   -8.586  10.975  1 12.961 ? 199  ALA B CB  1 
ATOM   5621 N  N   . HIS B 1 208 ? 31.319  -9      7.486   1 11.905 ? 200  HIS B N   1 
ATOM   5622 C  CA  . HIS B 1 208 ? 30.551  -8.565  6.342   1 12.567 ? 200  HIS B CA  1 
ATOM   5623 C  C   . HIS B 1 208 ? 30.692  -9.566  5.203   1 13.729 ? 200  HIS B C   1 
ATOM   5624 O  O   . HIS B 1 208 ? 31.037  -9.159  4.108   1 13.648 ? 200  HIS B O   1 
ATOM   5625 C  CB  . HIS B 1 208 ? 31.006  -7.148  5.928   1 14.382 ? 200  HIS B CB  1 
ATOM   5626 C  CG  . HIS B 1 208 ? 30.448  -6.068  6.82    1 11.666 ? 200  HIS B CG  1 
ATOM   5627 N  ND1 . HIS B 1 208 ? 29.087  -5.908  6.792   1 12.324 ? 200  HIS B ND1 1 
ATOM   5628 C  CD2 . HIS B 1 208 ? 30.947  -5.213  7.77    1 11.539 ? 200  HIS B CD2 1 
ATOM   5629 C  CE1 . HIS B 1 208 ? 28.72   -4.972  7.669   1 12.083 ? 200  HIS B CE1 1 
ATOM   5630 N  NE2 . HIS B 1 208 ? 29.847  -4.48   8.227   1 13.987 ? 200  HIS B NE2 1 
ATOM   5631 N  N   . PRO B 1 209 ? 30.321  -10.875 5.376   1 15.994 ? 201  PRO B N   1 
ATOM   5632 C  CA  . PRO B 1 209 ? 30.203  -11.771 4.245   1 12.142 ? 201  PRO B CA  1 
ATOM   5633 C  C   . PRO B 1 209 ? 28.972  -11.446 3.465   1 14.276 ? 201  PRO B C   1 
ATOM   5634 O  O   . PRO B 1 209 ? 28.012  -10.833 3.964   1 13.107 ? 201  PRO B O   1 
ATOM   5635 C  CB  . PRO B 1 209 ? 30.295  -13.182 4.891   1 15.245 ? 201  PRO B CB  1 
ATOM   5636 C  CG  . PRO B 1 209 ? 29.414  -12.907 6.167   1 12.314 ? 201  PRO B CG  1 
ATOM   5637 C  CD  . PRO B 1 209 ? 29.988  -11.563 6.641   1 11.534 ? 201  PRO B CD  1 
ATOM   5638 N  N   . LYS B 1 210 ? 29.039  -11.766 2.188   1 15.238 ? 202  LYS B N   1 
ATOM   5639 C  CA  . LYS B 1 210 ? 27.881  -11.474 1.376   1 13.357 ? 202  LYS B CA  1 
ATOM   5640 C  C   . LYS B 1 210 ? 27.327  -12.794 0.836   1 18.496 ? 202  LYS B C   1 
ATOM   5641 O  O   . LYS B 1 210 ? 28.07   -13.646 0.332   1 18.098 ? 202  LYS B O   1 
ATOM   5642 C  CB  . LYS B 1 210 ? 28.278  -10.539 0.218   1 13.842 ? 202  LYS B CB  1 
ATOM   5643 C  CG  . LYS B 1 210 ? 29.173  -9.265  0.57    1 12.201 ? 202  LYS B CG  1 
ATOM   5644 C  CD  . LYS B 1 210 ? 28.366  -8.3    1.447   1 12.744 ? 202  LYS B CD  1 
ATOM   5645 C  CE  . LYS B 1 210 ? 29.415  -7.361  2.077   1 11.805 ? 202  LYS B CE  1 
ATOM   5646 N  NZ  . LYS B 1 210 ? 28.773  -6.173  2.704   1 12.985 ? 202  LYS B NZ  1 
ATOM   5647 N  N   . GLN B 1 211 ? 26      -12.905 0.865   1 18.039 ? 203  GLN B N   1 
ATOM   5648 C  CA  . GLN B 1 211 ? 25.308  -14.081 0.339   1 16.59  ? 203  GLN B CA  1 
ATOM   5649 C  C   . GLN B 1 211 ? 24.801  -13.785 -1.059  1 15.813 ? 203  GLN B C   1 
ATOM   5650 O  O   . GLN B 1 211 ? 23.766  -13.154 -1.254  1 17.887 ? 203  GLN B O   1 
ATOM   5651 C  CB  . GLN B 1 211 ? 24.14   -14.525 1.192   1 16.908 ? 203  GLN B CB  1 
ATOM   5652 C  CG  . GLN B 1 211 ? 24.507  -14.782 2.653   1 20.315 ? 203  GLN B CG  1 
ATOM   5653 C  CD  . GLN B 1 211 ? 23.327  -15.314 3.441   1 21.932 ? 203  GLN B CD  1 
ATOM   5654 O  OE1 . GLN B 1 211 ? 22.399  -14.576 3.807   1 25.135 ? 203  GLN B OE1 1 
ATOM   5655 N  NE2 . GLN B 1 211 ? 23.331  -16.625 3.649   1 21.016 ? 203  GLN B NE2 1 
ATOM   5656 N  N   . CYS B 1 212 ? 25.528  -14.381 -1.98   1 16.914 ? 204  CYS B N   1 
ATOM   5657 C  CA  . CYS B 1 212 ? 25.37   -14.321 -3.419  1 15.242 ? 204  CYS B CA  1 
ATOM   5658 C  C   . CYS B 1 212 ? 23.962  -14.793 -3.807  1 18.657 ? 204  CYS B C   1 
ATOM   5659 O  O   . CYS B 1 212 ? 23.556  -15.919 -3.502  1 16.599 ? 204  CYS B O   1 
ATOM   5660 C  CB  . CYS B 1 212 ? 26.444  -15.233 -4.004  1 13.666 ? 204  CYS B CB  1 
ATOM   5661 S  SG  . CYS B 1 212 ? 26.393  -15.256 -5.829  1 19.178 ? 204  CYS B SG  1 
ATOM   5662 N  N   . SER B 1 213 ? 23.238  -13.941 -4.529  1 18.364 ? 205  SER B N   1 
ATOM   5663 C  CA  . SER B 1 213 ? 21.867  -14.295 -4.877  1 24.321 ? 205  SER B CA  1 
ATOM   5664 C  C   . SER B 1 213 ? 21.832  -15.272 -6.063  1 28.084 ? 205  SER B C   1 
ATOM   5665 O  O   . SER B 1 213 ? 20.741  -15.779 -6.341  1 22.454 ? 205  SER B O   1 
ATOM   5666 C  CB  . SER B 1 213 ? 21.011  -13.078 -5.142  1 27.791 ? 205  SER B CB  1 
ATOM   5667 O  OG  . SER B 1 213 ? 21.425  -12.409 -6.337  1 27.45  ? 205  SER B OG  1 
ATOM   5668 N  N   . VAL B 1 214 ? 22.998  -15.543 -6.696  1 22.842 ? 206  VAL B N   1 
ATOM   5669 C  CA  . VAL B 1 214 ? 23.036  -16.444 -7.841  1 22.326 ? 206  VAL B CA  1 
ATOM   5670 C  C   . VAL B 1 214 ? 23.35   -17.866 -7.369  1 26.479 ? 206  VAL B C   1 
ATOM   5671 O  O   . VAL B 1 214 ? 22.504  -18.768 -7.513  1 26.276 ? 206  VAL B O   1 
ATOM   5672 C  CB  . VAL B 1 214 ? 23.844  -15.989 -9.061  1 23.55  ? 206  VAL B CB  1 
ATOM   5673 C  CG1 . VAL B 1 214 ? 23.654  -16.913 -10.283 1 25.927 ? 206  VAL B CG1 1 
ATOM   5674 C  CG2 . VAL B 1 214 ? 23.451  -14.577 -9.443  1 18.444 ? 206  VAL B CG2 1 
ATOM   5675 N  N   . THR B 1 215 ? 24.514  -18.02  -6.699  1 21.049 ? 207  THR B N   1 
ATOM   5676 C  CA  . THR B 1 215 ? 25.015  -19.306 -6.229  1 22.471 ? 207  THR B CA  1 
ATOM   5677 C  C   . THR B 1 215 ? 24.456  -19.637 -4.838  1 21.426 ? 207  THR B C   1 
ATOM   5678 O  O   . THR B 1 215 ? 24.505  -20.784 -4.436  1 17.54  ? 207  THR B O   1 
ATOM   5679 C  CB  . THR B 1 215 ? 26.564  -19.29  -6.204  1 19.953 ? 207  THR B CB  1 
ATOM   5680 O  OG1 . THR B 1 215 ? 26.963  -18.431 -5.132  1 19.287 ? 207  THR B OG1 1 
ATOM   5681 C  CG2 . THR B 1 215 ? 27.229  -18.955 -7.53   1 17.312 ? 207  THR B CG2 1 
ATOM   5682 N  N   . GLY B 1 216 ? 24.061  -18.64  -4.022  1 20.916 ? 208  GLY B N   1 
ATOM   5683 C  CA  . GLY B 1 216 ? 23.708  -18.976 -2.637  1 23.173 ? 208  GLY B CA  1 
ATOM   5684 C  C   . GLY B 1 216 ? 24.921  -19.037 -1.708  1 22.657 ? 208  GLY B C   1 
ATOM   5685 O  O   . GLY B 1 216 ? 24.773  -19.264 -0.481  1 22.171 ? 208  GLY B O   1 
ATOM   5686 N  N   . ASN B 1 217 ? 26.132  -18.834 -2.276  1 21.557 ? 209  ASN B N   1 
ATOM   5687 C  CA  . ASN B 1 217 ? 27.382  -18.916 -1.514  1 16.847 ? 209  ASN B CA  1 
ATOM   5688 C  C   . ASN B 1 217 ? 27.538  -17.753 -0.537  1 16.848 ? 209  ASN B C   1 
ATOM   5689 O  O   . ASN B 1 217 ? 27.216  -16.616 -0.864  1 18.218 ? 209  ASN B O   1 
ATOM   5690 C  CB  . ASN B 1 217 ? 28.652  -18.942 -2.374  1 22.501 ? 209  ASN B CB  1 
ATOM   5691 C  CG  . ASN B 1 217 ? 28.753  -20.187 -3.242  1 24.784 ? 209  ASN B CG  1 
ATOM   5692 O  OD1 . ASN B 1 217 ? 27.891  -21.08  -3.137  1 19.015 ? 209  ASN B OD1 1 
ATOM   5693 N  ND2 . ASN B 1 217 ? 29.779  -20.253 -4.1    1 20.453 ? 209  ASN B ND2 1 
ATOM   5694 N  N   . LEU B 1 218 ? 27.999  -18.087 0.674   1 15.04  ? 210  LEU B N   1 
ATOM   5695 C  CA  . LEU B 1 218 ? 28.407  -17.07  1.624   1 15.426 ? 210  LEU B CA  1 
ATOM   5696 C  C   . LEU B 1 218 ? 29.824  -16.663 1.23    1 14.591 ? 210  LEU B C   1 
ATOM   5697 O  O   . LEU B 1 218 ? 30.76   -17.466 1.405   1 14.014 ? 210  LEU B O   1 
ATOM   5698 C  CB  . LEU B 1 218 ? 28.364  -17.607 3.079   1 11.098 ? 210  LEU B CB  1 
ATOM   5699 C  CG  . LEU B 1 218 ? 28.581  -16.534 4.16    1 14.678 ? 210  LEU B CG  1 
ATOM   5700 C  CD1 . LEU B 1 218 ? 27.461  -15.418 4.231   1 15.278 ? 210  LEU B CD1 1 
ATOM   5701 C  CD2 . LEU B 1 218 ? 28.673  -17.299 5.485   1 14.205 ? 210  LEU B CD2 1 
ATOM   5702 N  N   . VAL B 1 219 ? 29.983  -15.474 0.604   1 15.976 ? 211  VAL B N   1 
ATOM   5703 C  CA  . VAL B 1 219 ? 31.293  -15.132 0.094   1 16.135 ? 211  VAL B CA  1 
ATOM   5704 C  C   . VAL B 1 219 ? 31.922  -14.097 1.034   1 14.19  ? 211  VAL B C   1 
ATOM   5705 O  O   . VAL B 1 219 ? 31.267  -13.1   1.383   1 14.899 ? 211  VAL B O   1 
ATOM   5706 C  CB  . VAL B 1 219 ? 31.23   -14.546 -1.346  1 15.526 ? 211  VAL B CB  1 
ATOM   5707 C  CG1 . VAL B 1 219 ? 32.659  -14.269 -1.878  1 13.397 ? 211  VAL B CG1 1 
ATOM   5708 C  CG2 . VAL B 1 219 ? 30.329  -15.366 -2.286  1 14.866 ? 211  VAL B CG2 1 
ATOM   5709 N  N   . GLY B 1 220 ? 33.173  -14.319 1.4     1 15.267 ? 212  GLY B N   1 
ATOM   5710 C  CA  . GLY B 1 220 ? 33.773  -13.496 2.445   1 15.071 ? 212  GLY B CA  1 
ATOM   5711 C  C   . GLY B 1 220 ? 35.278  -13.689 2.461   1 13.014 ? 212  GLY B C   1 
ATOM   5712 O  O   . GLY B 1 220 ? 35.884  -14.188 1.535   1 12.391 ? 212  GLY B O   1 
ATOM   5713 N  N   . PHE B 1 221 ? 35.896  -13.25  3.562   1 12.495 ? 213  PHE B N   1 
ATOM   5714 C  CA  . PHE B 1 221 ? 37.34   -13.211 3.687   1 11.432 ? 213  PHE B CA  1 
ATOM   5715 C  C   . PHE B 1 221 ? 37.611  -13.118 5.196   1 11.796 ? 213  PHE B C   1 
ATOM   5716 O  O   . PHE B 1 221 ? 36.664  -12.838 5.931   1 12.424 ? 213  PHE B O   1 
ATOM   5717 C  CB  . PHE B 1 221 ? 37.919  -12.013 2.903   1 12.484 ? 213  PHE B CB  1 
ATOM   5718 C  CG  . PHE B 1 221 ? 37.546  -10.654 3.464   1 12.478 ? 213  PHE B CG  1 
ATOM   5719 C  CD1 . PHE B 1 221 ? 36.26   -10.119 3.233   1 12.608 ? 213  PHE B CD1 1 
ATOM   5720 C  CD2 . PHE B 1 221 ? 38.475  -9.987  4.29    1 13.196 ? 213  PHE B CD2 1 
ATOM   5721 C  CE1 . PHE B 1 221 ? 35.923  -8.87   3.768   1 12.456 ? 213  PHE B CE1 1 
ATOM   5722 C  CE2 . PHE B 1 221 ? 38.11   -8.757  4.863   1 11.886 ? 213  PHE B CE2 1 
ATOM   5723 C  CZ  . PHE B 1 221 ? 36.859  -8.231  4.623   1 10.96  ? 213  PHE B CZ  1 
ATOM   5724 N  N   . GLY B 1 222 ? 38.875  -13.331 5.595   1 14.08  ? 214  GLY B N   1 
ATOM   5725 C  CA  . GLY B 1 222 ? 39.308  -12.98  6.938   1 14.377 ? 214  GLY B CA  1 
ATOM   5726 C  C   . GLY B 1 222 ? 40.66   -12.285 6.799   1 16.904 ? 214  GLY B C   1 
ATOM   5727 O  O   . GLY B 1 222 ? 41.473  -12.821 6.061   1 21.072 ? 214  GLY B O   1 
ATOM   5728 N  N   . TYR B 1 223 ? 40.921  -11.107 7.452   1 14.321 ? 215  TYR B N   1 
ATOM   5729 C  CA  . TYR B 1 223 ? 42.261  -10.511 7.418   1 11.925 ? 215  TYR B CA  1 
ATOM   5730 C  C   . TYR B 1 223 ? 42.877  -10.655 8.808   1 12.145 ? 215  TYR B C   1 
ATOM   5731 O  O   . TYR B 1 223 ? 42.179  -11.134 9.71    1 13.391 ? 215  TYR B O   1 
ATOM   5732 C  CB  . TYR B 1 223 ? 42.175  -9.077  6.865   1 15.281 ? 215  TYR B CB  1 
ATOM   5733 C  CG  . TYR B 1 223 ? 41.611  -8.109  7.903   1 13.626 ? 215  TYR B CG  1 
ATOM   5734 C  CD1 . TYR B 1 223 ? 40.231  -7.954  8.042   1 12.544 ? 215  TYR B CD1 1 
ATOM   5735 C  CD2 . TYR B 1 223 ? 42.477  -7.391  8.779   1 15.93  ? 215  TYR B CD2 1 
ATOM   5736 C  CE1 . TYR B 1 223 ? 39.735  -7.066  9.007   1 15.986 ? 215  TYR B CE1 1 
ATOM   5737 C  CE2 . TYR B 1 223 ? 41.971  -6.497  9.722   1 17.493 ? 215  TYR B CE2 1 
ATOM   5738 C  CZ  . TYR B 1 223 ? 40.593  -6.373  9.869   1 16.195 ? 215  TYR B CZ  1 
ATOM   5739 O  OH  . TYR B 1 223 ? 40.066  -5.519  10.845  1 18.862 ? 215  TYR B OH  1 
ATOM   5740 N  N   . GLU B 1 224 ? 44.197  -10.366 8.919   1 12.21  ? 216  GLU B N   1 
ATOM   5741 C  CA  . GLU B 1 224 ? 45.028  -10.802 10.032  1 13.133 ? 216  GLU B CA  1 
ATOM   5742 C  C   . GLU B 1 224 ? 44.818  -12.31  10.216  1 14.646 ? 216  GLU B C   1 
ATOM   5743 O  O   . GLU B 1 224 ? 44.627  -12.776 11.36   1 15.655 ? 216  GLU B O   1 
ATOM   5744 C  CB  . GLU B 1 224 ? 44.785  -9.995  11.326  1 11.681 ? 216  GLU B CB  1 
ATOM   5745 C  CG  . GLU B 1 224 ? 45.062  -8.48   11.121  1 13.241 ? 216  GLU B CG  1 
ATOM   5746 C  CD  . GLU B 1 224 ? 45.165  -7.61   12.359  1 17.956 ? 216  GLU B CD  1 
ATOM   5747 O  OE1 . GLU B 1 224 ? 45.56   -8.203  13.401  1 14.757 ? 216  GLU B OE1 1 
ATOM   5748 O  OE2 . GLU B 1 224 ? 44.908  -6.358  12.359  1 16.524 ? 216  GLU B OE2 1 
ATOM   5749 N  N   . ALA B 1 225 ? 44.817  -13.042 9.071   1 13.492 ? 217  ALA B N   1 
ATOM   5750 C  CA  . ALA B 1 225 ? 44.286  -14.411 9.045   1 14.013 ? 217  ALA B CA  1 
ATOM   5751 C  C   . ALA B 1 225 ? 45.224  -15.37  9.776   1 17.102 ? 217  ALA B C   1 
ATOM   5752 O  O   . ALA B 1 225 ? 44.81   -16.477 10.166  1 15.561 ? 217  ALA B O   1 
ATOM   5753 C  CB  . ALA B 1 225 ? 44.131  -14.83  7.6     1 14.891 ? 217  ALA B CB  1 
ATOM   5754 N  N   . LYS B 1 226 ? 46.485  -14.93  9.959   1 17.331 ? 218  LYS B N   1 
ATOM   5755 C  CA  . LYS B 1 226 ? 47.465  -15.769 10.642  1 18.478 ? 218  LYS B CA  1 
ATOM   5756 C  C   . LYS B 1 226 ? 47.78   -15.251 12.034  1 16.969 ? 218  LYS B C   1 
ATOM   5757 O  O   . LYS B 1 226 ? 48.645  -15.824 12.677  1 16.321 ? 218  LYS B O   1 
ATOM   5758 C  CB  . LYS B 1 226 ? 48.726  -16.089 9.844   1 17.462 ? 218  LYS B CB  1 
ATOM   5759 C  CG  . LYS B 1 226 ? 48.432  -16.764 8.501   1 19.747 ? 218  LYS B CG  1 
ATOM   5760 C  CD  . LYS B 1 226 ? 49.721  -17.314 7.875   1 20.878 ? 218  LYS B CD  1 
ATOM   5761 C  CE  . LYS B 1 226 ? 49.466  -17.924 6.537   1 25.098 ? 218  LYS B CE  1 
ATOM   5762 N  NZ  . LYS B 1 226 ? 50.609  -18.678 6.002   1 27.72  ? 218  LYS B NZ  1 
ATOM   5763 N  N   . GLY B 1 227 ? 47.039  -14.261 12.532  1 16.361 ? 219  GLY B N   1 
ATOM   5764 C  CA  . GLY B 1 227 ? 47.315  -13.744 13.878  1 17.883 ? 219  GLY B CA  1 
ATOM   5765 C  C   . GLY B 1 227 ? 47.533  -12.228 13.885  1 15.074 ? 219  GLY B C   1 
ATOM   5766 O  O   . GLY B 1 227 ? 47.507  -11.602 12.833  1 15.761 ? 219  GLY B O   1 
ATOM   5767 N  N   . LEU B 1 228 ? 47.829  -11.646 15.069  1 13.097 ? 220  LEU B N   1 
ATOM   5768 C  CA  . LEU B 1 228 ? 47.833  -10.206 15.261  1 14.27  ? 220  LEU B CA  1 
ATOM   5769 C  C   . LEU B 1 228 ? 48.853  -9.536  14.323  1 16.979 ? 220  LEU B C   1 
ATOM   5770 O  O   . LEU B 1 228 ? 49.991  -9.969  14.214  1 17.238 ? 220  LEU B O   1 
ATOM   5771 C  CB  . LEU B 1 228 ? 48.294  -10.261 16.722  1 19.324 ? 220  LEU B CB  1 
ATOM   5772 C  CG  . LEU B 1 228 ? 47.802  -9.245  17.748  1 25.028 ? 220  LEU B CG  1 
ATOM   5773 C  CD1 . LEU B 1 228 ? 46.254  -8.994  17.822  1 15.949 ? 220  LEU B CD1 1 
ATOM   5774 C  CD2 . LEU B 1 228 ? 48.369  -9.816  19.054  1 18.814 ? 220  LEU B CD2 1 
ATOM   5775 N  N   . ALA B 1 229 ? 48.379  -8.543  13.569  1 16.67  ? 221  ALA B N   1 
ATOM   5776 C  CA  . ALA B 1 229 ? 49.178  -7.689  12.711  1 18.569 ? 221  ALA B CA  1 
ATOM   5777 C  C   . ALA B 1 229 ? 49.673  -8.418  11.452  1 21.161 ? 221  ALA B C   1 
ATOM   5778 O  O   . ALA B 1 229 ? 50.486  -7.851  10.736  1 19.182 ? 221  ALA B O   1 
ATOM   5779 C  CB  . ALA B 1 229 ? 50.341  -7.033  13.471  1 17.156 ? 221  ALA B CB  1 
ATOM   5780 N  N   . THR B 1 230 ? 49.19   -9.642  11.16   1 18.721 ? 222  THR B N   1 
ATOM   5781 C  CA  . THR B 1 230 ? 49.619  -10.353 9.966   1 13.266 ? 222  THR B CA  1 
ATOM   5782 C  C   . THR B 1 230 ? 48.944  -9.742  8.75    1 15.45  ? 222  THR B C   1 
ATOM   5783 O  O   . THR B 1 230 ? 47.807  -9.263  8.821   1 15.044 ? 222  THR B O   1 
ATOM   5784 C  CB  . THR B 1 230 ? 49.406  -11.876 10.028  1 15.301 ? 222  THR B CB  1 
ATOM   5785 O  OG1 . THR B 1 230 ? 47.998  -12.131 10.23   1 16.592 ? 222  THR B OG1 1 
ATOM   5786 C  CG2 . THR B 1 230 ? 50.256  -12.538 11.096  1 17.122 ? 222  THR B CG2 1 
ATOM   5787 N  N   . LYS B 1 231 ? 49.669  -9.765  7.643   1 14.85  ? 223  LYS B N   1 
ATOM   5788 C  CA  . LYS B 1 231 ? 49.15   -9.233  6.372   1 18.752 ? 223  LYS B CA  1 
ATOM   5789 C  C   . LYS B 1 231 ? 48.276  -10.235 5.634   1 17.531 ? 223  LYS B C   1 
ATOM   5790 O  O   . LYS B 1 231 ? 47.603  -9.88   4.691   1 15.654 ? 223  LYS B O   1 
ATOM   5791 C  CB  . LYS B 1 231 ? 50.31   -8.687  5.531   1 18.173 ? 223  LYS B CB  1 
ATOM   5792 C  CG  . LYS B 1 231 ? 50.906  -7.374  6.147   1 19.43  ? 223  LYS B CG  1 
ATOM   5793 C  CD  . LYS B 1 231 ? 52.09   -6.715  5.407   1 25.887 ? 223  LYS B CD  1 
ATOM   5794 C  CE  . LYS B 1 231 ? 52.916  -7.72   4.668   1 25.122 ? 223  LYS B CE  1 
ATOM   5795 N  NZ  . LYS B 1 231 ? 54.111  -7.068  4.119   1 35.149 ? 223  LYS B NZ  1 
ATOM   5796 N  N   . ASP B 1 232 ? 48.276  -11.51  6.048   1 17.336 ? 224  ASP B N   1 
ATOM   5797 C  CA  . ASP B 1 232 ? 47.483  -12.563 5.435   1 16.751 ? 224  ASP B CA  1 
ATOM   5798 C  C   . ASP B 1 232 ? 45.981  -12.239 5.384   1 18.886 ? 224  ASP B C   1 
ATOM   5799 O  O   . ASP B 1 232 ? 45.384  -11.819 6.374   1 15.678 ? 224  ASP B O   1 
ATOM   5800 C  CB  . ASP B 1 232 ? 47.72   -13.892 6.126   1 18.516 ? 224  ASP B CB  1 
ATOM   5801 C  CG  . ASP B 1 232 ? 49.216  -14.187 6.195   1 21.691 ? 224  ASP B CG  1 
ATOM   5802 O  OD1 . ASP B 1 232 ? 49.741  -14.698 5.18    1 21.91  ? 224  ASP B OD1 1 
ATOM   5803 O  OD2 . ASP B 1 232 ? 49.85   -13.795 7.219   1 20.309 ? 224  ASP B OD2 1 
ATOM   5804 N  N   . VAL B 1 233 ? 45.427  -12.426 4.184   1 14.069 ? 225  VAL B N   1 
ATOM   5805 C  CA  . VAL B 1 233 ? 44.002  -12.467 3.919   1 17.334 ? 225  VAL B CA  1 
ATOM   5806 C  C   . VAL B 1 233 ? 43.652  -13.835 3.35    1 18.16  ? 225  VAL B C   1 
ATOM   5807 O  O   . VAL B 1 233 ? 44.265  -14.289 2.395   1 16.18  ? 225  VAL B O   1 
ATOM   5808 C  CB  . VAL B 1 233 ? 43.596  -11.297 2.985   1 14.962 ? 225  VAL B CB  1 
ATOM   5809 C  CG1 . VAL B 1 233 ? 42.13   -11.332 2.613   1 14.759 ? 225  VAL B CG1 1 
ATOM   5810 C  CG2 . VAL B 1 233 ? 43.972  -9.957  3.641   1 15.288 ? 225  VAL B CG2 1 
ATOM   5811 N  N   . TYR B 1 234 ? 42.521  -14.391 3.85    1 19.636 ? 226  TYR B N   1 
ATOM   5812 C  CA  . TYR B 1 234 ? 41.968  -15.66  3.381   1 18.731 ? 226  TYR B CA  1 
ATOM   5813 C  C   . TYR B 1 234 ? 40.595  -15.378 2.769   1 17.435 ? 226  TYR B C   1 
ATOM   5814 O  O   . TYR B 1 234 ? 39.698  -14.894 3.441   1 16.171 ? 226  TYR B O   1 
ATOM   5815 C  CB  . TYR B 1 234 ? 41.917  -16.629 4.578   1 16.815 ? 226  TYR B CB  1 
ATOM   5816 C  CG  . TYR B 1 234 ? 41.112  -17.897 4.279   1 19.01  ? 226  TYR B CG  1 
ATOM   5817 C  CD1 . TYR B 1 234 ? 41.645  -18.859 3.405   1 17.212 ? 226  TYR B CD1 1 
ATOM   5818 C  CD2 . TYR B 1 234 ? 39.849  -18.145 4.853   1 15.959 ? 226  TYR B CD2 1 
ATOM   5819 C  CE1 . TYR B 1 234 ? 40.939  -20.023 3.108   1 16.894 ? 226  TYR B CE1 1 
ATOM   5820 C  CE2 . TYR B 1 234 ? 39.139  -19.307 4.554   1 17.99  ? 226  TYR B CE2 1 
ATOM   5821 C  CZ  . TYR B 1 234 ? 39.69   -20.224 3.651   1 19.649 ? 226  TYR B CZ  1 
ATOM   5822 O  OH  . TYR B 1 234 ? 39.092  -21.392 3.341   1 17.066 ? 226  TYR B OH  1 
ATOM   5823 N  N   . TYR B 1 235 ? 40.443  -15.611 1.445   1 14.795 ? 227  TYR B N   1 
ATOM   5824 C  CA  . TYR B 1 235 ? 39.201  -15.465 0.721   1 12.79  ? 227  TYR B CA  1 
ATOM   5825 C  C   . TYR B 1 235 ? 38.462  -16.814 0.712   1 13.638 ? 227  TYR B C   1 
ATOM   5826 O  O   . TYR B 1 235 ? 39.103  -17.845 0.575   1 14.094 ? 227  TYR B O   1 
ATOM   5827 C  CB  . TYR B 1 235 ? 39.532  -15.036 -0.716  1 13.361 ? 227  TYR B CB  1 
ATOM   5828 C  CG  . TYR B 1 235 ? 38.541  -15.531 -1.754  1 18.346 ? 227  TYR B CG  1 
ATOM   5829 C  CD1 . TYR B 1 235 ? 37.234  -14.987 -1.88   1 17.649 ? 227  TYR B CD1 1 
ATOM   5830 C  CD2 . TYR B 1 235 ? 38.932  -16.531 -2.647  1 20.416 ? 227  TYR B CD2 1 
ATOM   5831 C  CE1 . TYR B 1 235 ? 36.366  -15.429 -2.887  1 17     ? 227  TYR B CE1 1 
ATOM   5832 C  CE2 . TYR B 1 235 ? 38.028  -17.045 -3.581  1 16.915 ? 227  TYR B CE2 1 
ATOM   5833 C  CZ  . TYR B 1 235 ? 36.764  -16.486 -3.708  1 16.27  ? 227  TYR B CZ  1 
ATOM   5834 O  OH  . TYR B 1 235 ? 35.953  -16.96  -4.708  1 15.858 ? 227  TYR B OH  1 
ATOM   5835 N  N   . PHE B 1 236 ? 37.126  -16.804 0.847   1 13.085 ? 228  PHE B N   1 
ATOM   5836 C  CA  . PHE B 1 236 ? 36.364  -18.053 0.828   1 15.947 ? 228  PHE B CA  1 
ATOM   5837 C  C   . PHE B 1 236 ? 35.006  -17.834 0.166   1 15.827 ? 228  PHE B C   1 
ATOM   5838 O  O   . PHE B 1 236 ? 34.437  -16.716 0.171   1 17.113 ? 228  PHE B O   1 
ATOM   5839 C  CB  . PHE B 1 236 ? 36.332  -18.677 2.226   1 16.987 ? 228  PHE B CB  1 
ATOM   5840 C  CG  . PHE B 1 236 ? 35.551  -17.79  3.182   1 18.568 ? 228  PHE B CG  1 
ATOM   5841 C  CD1 . PHE B 1 236 ? 34.16   -17.851 3.187   1 17.122 ? 228  PHE B CD1 1 
ATOM   5842 C  CD2 . PHE B 1 236 ? 36.193  -16.886 4.03    1 20.966 ? 228  PHE B CD2 1 
ATOM   5843 C  CE1 . PHE B 1 236 ? 33.424  -17.024 4.013   1 18.665 ? 228  PHE B CE1 1 
ATOM   5844 C  CE2 . PHE B 1 236 ? 35.432  -16.098 4.913   1 18.121 ? 228  PHE B CE2 1 
ATOM   5845 C  CZ  . PHE B 1 236 ? 34.071  -16.148 4.867   1 19.259 ? 228  PHE B CZ  1 
ATOM   5846 N  N   . GLU B 1 237 ? 34.444  -18.946 -0.366  1 14.275 ? 229  GLU B N   1 
ATOM   5847 C  CA  . GLU B 1 237 ? 33.004  -19.089 -0.559  1 15.69  ? 229  GLU B CA  1 
ATOM   5848 C  C   . GLU B 1 237 ? 32.553  -20.369 0.15    1 17.547 ? 229  GLU B C   1 
ATOM   5849 O  O   . GLU B 1 237 ? 33.109  -21.434 -0.081  1 19.331 ? 229  GLU B O   1 
ATOM   5850 C  CB  . GLU B 1 237 ? 32.707  -19.134 -2.079  1 15.929 ? 229  GLU B CB  1 
ATOM   5851 C  CG  . GLU B 1 237 ? 33.254  -17.856 -2.731  1 14.931 ? 229  GLU B CG  1 
ATOM   5852 C  CD  . GLU B 1 237 ? 32.683  -17.472 -4.075  1 17.366 ? 229  GLU B CD  1 
ATOM   5853 O  OE1 . GLU B 1 237 ? 31.565  -17.906 -4.317  1 16.359 ? 229  GLU B OE1 1 
ATOM   5854 O  OE2 . GLU B 1 237 ? 33.302  -16.688 -4.807  1 19.895 ? 229  GLU B OE2 1 
ATOM   5855 N  N   . VAL B 1 238 ? 31.556  -20.257 1.025   1 19.004 ? 230  VAL B N   1 
ATOM   5856 C  CA  . VAL B 1 238 ? 30.909  -21.389 1.677   1 18.794 ? 230  VAL B CA  1 
ATOM   5857 C  C   . VAL B 1 238 ? 29.6    -21.613 0.938   1 18.142 ? 230  VAL B C   1 
ATOM   5858 O  O   . VAL B 1 238 ? 28.783  -20.697 0.856   1 19.744 ? 230  VAL B O   1 
ATOM   5859 C  CB  . VAL B 1 238 ? 30.661  -21.119 3.185   1 17.402 ? 230  VAL B CB  1 
ATOM   5860 C  CG1 . VAL B 1 238 ? 29.84   -22.217 3.844   1 14.76  ? 230  VAL B CG1 1 
ATOM   5861 C  CG2 . VAL B 1 238 ? 31.976  -20.976 3.943   1 18.743 ? 230  VAL B CG2 1 
ATOM   5862 N  N   . ASP B 1 239 ? 29.383  -22.837 0.393   1 18.914 ? 231  ASP B N   1 
ATOM   5863 C  CA  . ASP B 1 239 ? 28.176  -23.089 -0.402  1 18.545 ? 231  ASP B CA  1 
ATOM   5864 C  C   . ASP B 1 239 ? 26.954  -23.229 0.504   1 18.24  ? 231  ASP B C   1 
ATOM   5865 O  O   . ASP B 1 239 ? 27.147  -23.265 1.751   1 17.129 ? 231  ASP B O   1 
ATOM   5866 C  CB  . ASP B 1 239 ? 28.394  -24.216 -1.403  1 22.297 ? 231  ASP B CB  1 
ATOM   5867 C  CG  . ASP B 1 239 ? 28.375  -25.627 -0.819  1 24.403 ? 231  ASP B CG  1 
ATOM   5868 O  OD1 . ASP B 1 239 ? 28.173  -25.822 0.438   1 19.949 ? 231  ASP B OD1 1 
ATOM   5869 O  OD2 . ASP B 1 239 ? 28.506  -26.531 -1.64   1 23.771 ? 231  ASP B OD2 1 
ATOM   5870 N  N   . PRO B 1 240 ? 25.697  -23.346 -0.041  1 21.007 ? 232  PRO B N   1 
ATOM   5871 C  CA  . PRO B 1 240 ? 24.472  -23.54  0.752   1 23.602 ? 232  PRO B CA  1 
ATOM   5872 C  C   . PRO B 1 240 ? 24.46   -24.747 1.691   1 24.678 ? 232  PRO B C   1 
ATOM   5873 O  O   . PRO B 1 240 ? 23.614  -24.829 2.571   1 18.68  ? 232  PRO B O   1 
ATOM   5874 C  CB  . PRO B 1 240 ? 23.503  -23.87  -0.38   1 23.368 ? 232  PRO B CB  1 
ATOM   5875 C  CG  . PRO B 1 240 ? 23.93   -22.77  -1.339  1 19.742 ? 232  PRO B CG  1 
ATOM   5876 C  CD  . PRO B 1 240 ? 25.309  -23.229 -1.483  1 18.784 ? 232  PRO B CD  1 
ATOM   5877 N  N   . SER B 1 241 ? 25.435  -25.663 1.525   1 26.835 ? 233  SER B N   1 
ATOM   5878 C  CA  . SER B 1 241 ? 25.513  -26.891 2.301   1 23.63  ? 233  SER B CA  1 
ATOM   5879 C  C   . SER B 1 241 ? 26.44   -26.678 3.485   1 26.678 ? 233  SER B C   1 
ATOM   5880 O  O   . SER B 1 241 ? 26.505  -27.543 4.352   1 26.09  ? 233  SER B O   1 
ATOM   5881 C  CB  . SER B 1 241 ? 25.951  -28.078 1.401   1 29.413 ? 233  SER B CB  1 
ATOM   5882 O  OG  . SER B 1 241 ? 27.389  -28.199 1.355   1 23.733 ? 233  SER B OG  1 
ATOM   5883 N  N   . GLY B 1 242 ? 27.2    -25.549 3.504   1 23.449 ? 234  GLY B N   1 
ATOM   5884 C  CA  . GLY B 1 242 ? 28.089  -25.253 4.618   1 20.644 ? 234  GLY B CA  1 
ATOM   5885 C  C   . GLY B 1 242 ? 29.524  -25.78  4.461   1 25.36  ? 234  GLY B C   1 
ATOM   5886 O  O   . GLY B 1 242 ? 30.224  -25.96  5.469   1 32.273 ? 234  GLY B O   1 
ATOM   5887 N  N   . LYS B 1 243 ? 29.974  -25.988 3.21    1 25.531 ? 235  LYS B N   1 
ATOM   5888 C  CA  . LYS B 1 243 ? 31.332  -26.423 2.889   1 26.625 ? 235  LYS B CA  1 
ATOM   5889 C  C   . LYS B 1 243 ? 32.038  -25.296 2.134   1 22.287 ? 235  LYS B C   1 
ATOM   5890 O  O   . LYS B 1 243 ? 31.43   -24.705 1.245   1 18.5   ? 235  LYS B O   1 
ATOM   5891 C  CB  . LYS B 1 243 ? 31.2    -27.661 1.993   1 30.613 ? 235  LYS B CB  1 
ATOM   5892 C  CG  . LYS B 1 243 ? 32.33   -28.193 1.154   1 39.818 ? 235  LYS B CG  1 
ATOM   5893 C  CD  . LYS B 1 243 ? 31.805  -29.076 0.019   1 38.907 ? 235  LYS B CD  1 
ATOM   5894 C  CE  . LYS B 1 243 ? 32.648  -29.033 -1.226  1 41.162 ? 235  LYS B CE  1 
ATOM   5895 N  NZ  . LYS B 1 243 ? 32.175  -29.551 -2.523  1 28.167 ? 235  LYS B NZ  1 
ATOM   5896 N  N   . VAL B 1 244 ? 33.34   -25.084 2.442   1 22.693 ? 236  VAL B N   1 
ATOM   5897 C  CA  . VAL B 1 244 ? 34.119  -24.137 1.666   1 18.795 ? 236  VAL B CA  1 
ATOM   5898 C  C   . VAL B 1 244 ? 34.305  -24.81  0.296   1 19.034 ? 236  VAL B C   1 
ATOM   5899 O  O   . VAL B 1 244 ? 34.946  -25.877 0.208   1 24.088 ? 236  VAL B O   1 
ATOM   5900 C  CB  . VAL B 1 244 ? 35.466  -23.787 2.34    1 24.114 ? 236  VAL B CB  1 
ATOM   5901 C  CG1 . VAL B 1 244 ? 36.387  -23.048 1.398   1 20.844 ? 236  VAL B CG1 1 
ATOM   5902 C  CG2 . VAL B 1 244 ? 35.347  -22.889 3.564   1 20.66  ? 236  VAL B CG2 1 
ATOM   5903 N  N   . VAL B 1 245 ? 33.809  -24.166 -0.732  1 16.409 ? 237  VAL B N   1 
ATOM   5904 C  CA  . VAL B 1 245 ? 33.909  -24.657 -2.11   1 20.866 ? 237  VAL B CA  1 
ATOM   5905 C  C   . VAL B 1 245 ? 34.999  -23.943 -2.913  1 26.899 ? 237  VAL B C   1 
ATOM   5906 O  O   . VAL B 1 245 ? 35.452  -24.481 -3.94   1 24.359 ? 237  VAL B O   1 
ATOM   5907 C  CB  . VAL B 1 245 ? 32.6    -24.716 -2.923  1 22.713 ? 237  VAL B CB  1 
ATOM   5908 C  CG1 . VAL B 1 245 ? 31.712  -25.797 -2.365  1 23.565 ? 237  VAL B CG1 1 
ATOM   5909 C  CG2 . VAL B 1 245 ? 31.841  -23.375 -3.003  1 26.772 ? 237  VAL B CG2 1 
ATOM   5910 N  N   . ARG B 1 246 ? 35.4    -22.748 -2.454  1 21.538 ? 238  ARG B N   1 
ATOM   5911 C  CA  . ARG B 1 246 ? 36.451  -21.963 -3.091  1 21.568 ? 238  ARG B CA  1 
ATOM   5912 C  C   . ARG B 1 246 ? 37.209  -21.252 -1.978  1 23.265 ? 238  ARG B C   1 
ATOM   5913 O  O   . ARG B 1 246 ? 36.562  -20.806 -1.047  1 19.071 ? 238  ARG B O   1 
ATOM   5914 C  CB  . ARG B 1 246 ? 35.82   -20.875 -3.963  1 22.558 ? 238  ARG B CB  1 
ATOM   5915 C  CG  . ARG B 1 246 ? 35.375  -21.401 -5.314  1 22.297 ? 238  ARG B CG  1 
ATOM   5916 C  CD  . ARG B 1 246 ? 34.429  -20.317 -5.768  1 24.171 ? 238  ARG B CD  1 
ATOM   5917 N  NE  . ARG B 1 246 ? 34.13   -20.547 -7.195  1 27.886 ? 238  ARG B NE  1 
ATOM   5918 C  CZ  . ARG B 1 246 ? 33.24   -19.819 -7.911  1 27.459 ? 238  ARG B CZ  1 
ATOM   5919 N  NH1 . ARG B 1 246 ? 32.714  -18.671 -7.458  1 29.545 ? 238  ARG B NH1 1 
ATOM   5920 N  NH2 . ARG B 1 246 ? 32.98   -20.18  -9.153  1 31.872 ? 238  ARG B NH2 1 
ATOM   5921 N  N   . ASP B 1 247 ? 38.537  -21.153 -2.096  1 18.048 ? 239  ASP B N   1 
ATOM   5922 C  CA  . ASP B 1 247 ? 39.283  -20.257 -1.215  1 18.936 ? 239  ASP B CA  1 
ATOM   5923 C  C   . ASP B 1 247 ? 40.586  -19.829 -1.889  1 20.325 ? 239  ASP B C   1 
ATOM   5924 O  O   . ASP B 1 247 ? 40.918  -20.309 -2.989  1 19.074 ? 239  ASP B O   1 
ATOM   5925 C  CB  . ASP B 1 247 ? 39.385  -20.892 0.174   1 18.487 ? 239  ASP B CB  1 
ATOM   5926 C  CG  . ASP B 1 247 ? 40.351  -22.078 0.305   1 23.144 ? 239  ASP B CG  1 
ATOM   5927 O  OD1 . ASP B 1 247 ? 41.02   -22.425 -0.7    1 23.975 ? 239  ASP B OD1 1 
ATOM   5928 O  OD2 . ASP B 1 247 ? 40.407  -22.687 1.41    1 18.653 ? 239  ASP B OD2 1 
ATOM   5929 N  N   . LEU B 1 248 ? 41.347  -18.955 -1.206  1 16.73  ? 240  LEU B N   1 
ATOM   5930 C  CA  . LEU B 1 248 ? 42.638  -18.439 -1.678  1 19.119 ? 240  LEU B CA  1 
ATOM   5931 C  C   . LEU B 1 248 ? 43.313  -17.72  -0.517  1 16.807 ? 240  LEU B C   1 
ATOM   5932 O  O   . LEU B 1 248 ? 42.652  -16.952 0.179   1 18.75  ? 240  LEU B O   1 
ATOM   5933 C  CB  . LEU B 1 248 ? 42.512  -17.471 -2.863  1 18.537 ? 240  LEU B CB  1 
ATOM   5934 C  CG  . LEU B 1 248 ? 43.833  -17.085 -3.537  1 20.452 ? 240  LEU B CG  1 
ATOM   5935 C  CD1 . LEU B 1 248 ? 44.572  -18.24  -4.244  1 22.648 ? 240  LEU B CD1 1 
ATOM   5936 C  CD2 . LEU B 1 248 ? 43.585  -15.9   -4.469  1 20.836 ? 240  LEU B CD2 1 
ATOM   5937 N  N   . TRP B 1 249 ? 44.623  -17.91  -0.389  1 18.445 ? 241  TRP B N   1 
ATOM   5938 C  CA  . TRP B 1 249 ? 45.399  -17.122 0.551   1 18.109 ? 241  TRP B CA  1 
ATOM   5939 C  C   . TRP B 1 249 ? 46.191  -16.078 -0.237  1 20.333 ? 241  TRP B C   1 
ATOM   5940 O  O   . TRP B 1 249 ? 46.685  -16.321 -1.358  1 18.985 ? 241  TRP B O   1 
ATOM   5941 C  CB  . TRP B 1 249 ? 46.32   -18.019 1.352   1 20.921 ? 241  TRP B CB  1 
ATOM   5942 C  CG  . TRP B 1 249 ? 45.594  -18.904 2.323   1 19.237 ? 241  TRP B CG  1 
ATOM   5943 C  CD1 . TRP B 1 249 ? 44.956  -20.08  2.064   1 17.25  ? 241  TRP B CD1 1 
ATOM   5944 C  CD2 . TRP B 1 249 ? 45.494  -18.673 3.748   1 18.295 ? 241  TRP B CD2 1 
ATOM   5945 N  NE1 . TRP B 1 249 ? 44.488  -20.619 3.243   1 16.895 ? 241  TRP B NE1 1 
ATOM   5946 C  CE2 . TRP B 1 249 ? 44.819  -19.79  4.286   1 17.068 ? 241  TRP B CE2 1 
ATOM   5947 C  CE3 . TRP B 1 249 ? 45.936  -17.657 4.614   1 20.267 ? 241  TRP B CE3 1 
ATOM   5948 C  CZ2 . TRP B 1 249 ? 44.515  -19.905 5.651   1 20.133 ? 241  TRP B CZ2 1 
ATOM   5949 C  CZ3 . TRP B 1 249 ? 45.603  -17.757 5.957   1 20.384 ? 241  TRP B CZ3 1 
ATOM   5950 C  CH2 . TRP B 1 249 ? 44.946  -18.896 6.473   1 19.218 ? 241  TRP B CH2 1 
ATOM   5951 N  N   . LEU B 1 250 ? 46.187  -14.87  0.319   1 17.997 ? 242  LEU B N   1 
ATOM   5952 C  CA  . LEU B 1 250 ? 46.806  -13.698 -0.285  1 16.474 ? 242  LEU B CA  1 
ATOM   5953 C  C   . LEU B 1 250 ? 47.218  -12.791 0.866   1 16.004 ? 242  LEU B C   1 
ATOM   5954 O  O   . LEU B 1 250 ? 47.216  -13.181 2.05    1 13.588 ? 242  LEU B O   1 
ATOM   5955 C  CB  . LEU B 1 250 ? 45.793  -13.06  -1.242  1 18.318 ? 242  LEU B CB  1 
ATOM   5956 C  CG  . LEU B 1 250 ? 44.463  -12.601 -0.603  1 18.692 ? 242  LEU B CG  1 
ATOM   5957 C  CD1 . LEU B 1 250 ? 44.04   -11.186 -1.019  1 18.416 ? 242  LEU B CD1 1 
ATOM   5958 C  CD2 . LEU B 1 250 ? 43.331  -13.559 -0.991  1 20.409 ? 242  LEU B CD2 1 
ATOM   5959 N  N   . GLU B 1 251 ? 47.635  -11.564 0.503   1 19.57  ? 243  GLU B N   1 
ATOM   5960 C  CA  . GLU B 1 251 ? 48.077  -10.565 1.463   1 18.781 ? 243  GLU B CA  1 
ATOM   5961 C  C   . GLU B 1 251 ? 47.534  -9.204  1.094   1 17.669 ? 243  GLU B C   1 
ATOM   5962 O  O   . GLU B 1 251 ? 47.271  -8.939  -0.084  1 15.791 ? 243  GLU B O   1 
ATOM   5963 C  CB  . GLU B 1 251 ? 49.592  -10.463 1.516   1 22.121 ? 243  GLU B CB  1 
ATOM   5964 C  CG  . GLU B 1 251 ? 50.233  -11.663 2.216   1 29.194 ? 243  GLU B CG  1 
ATOM   5965 C  CD  . GLU B 1 251 ? 51.743  -11.71  2.163   1 29.061 ? 243  GLU B CD  1 
ATOM   5966 O  OE1 . GLU B 1 251 ? 52.284  -11.762 1.05    1 35.356 ? 243  GLU B OE1 1 
ATOM   5967 O  OE2 . GLU B 1 251 ? 52.362  -11.701 3.237   1 31.787 ? 243  GLU B OE2 1 
ATOM   5968 N  N   . ALA B 1 252 ? 47.349  -8.4    2.145   1 15.305 ? 244  ALA B N   1 
ATOM   5969 C  CA  . ALA B 1 252 ? 47.06   -6.993  1.984   1 16.749 ? 244  ALA B CA  1 
ATOM   5970 C  C   . ALA B 1 252 ? 48.396  -6.252  1.798   1 18.492 ? 244  ALA B C   1 
ATOM   5971 O  O   . ALA B 1 252 ? 49.414  -6.732  2.303   1 18.306 ? 244  ALA B O   1 
ATOM   5972 C  CB  . ALA B 1 252 ? 46.308  -6.476  3.209   1 13.91  ? 244  ALA B CB  1 
ATOM   5973 N  N   . PRO B 1 253 ? 48.44   -5.092  1.078   1 19.239 ? 245  PRO B N   1 
ATOM   5974 C  CA  . PRO B 1 253 ? 49.689  -4.349  0.901   1 18.956 ? 245  PRO B CA  1 
ATOM   5975 C  C   . PRO B 1 253 ? 50.282  -3.83   2.218   1 18.515 ? 245  PRO B C   1 
ATOM   5976 O  O   . PRO B 1 253 ? 51.519  -3.67   2.359   1 23.4   ? 245  PRO B O   1 
ATOM   5977 C  CB  . PRO B 1 253 ? 49.294  -3.146  0.07    1 17.453 ? 245  PRO B CB  1 
ATOM   5978 C  CG  . PRO B 1 253 ? 47.751  -3.095  0.076   1 17.36  ? 245  PRO B CG  1 
ATOM   5979 C  CD  . PRO B 1 253 ? 47.287  -4.5    0.354   1 17.258 ? 245  PRO B CD  1 
ATOM   5980 N  N   . TRP B 1 254 ? 49.391  -3.539  3.171   1 16.565 ? 246  TRP B N   1 
ATOM   5981 C  CA  . TRP B 1 254 ? 49.814  -3.27   4.559   1 12.875 ? 246  TRP B CA  1 
ATOM   5982 C  C   . TRP B 1 254 ? 48.887  -4.01   5.498   1 13.906 ? 246  TRP B C   1 
ATOM   5983 O  O   . TRP B 1 254 ? 47.866  -4.451  5.038   1 12.812 ? 246  TRP B O   1 
ATOM   5984 C  CB  . TRP B 1 254 ? 49.919  -1.775  4.95    1 16.01  ? 246  TRP B CB  1 
ATOM   5985 C  CG  . TRP B 1 254 ? 48.641  -0.976  5.127   1 17.309 ? 246  TRP B CG  1 
ATOM   5986 C  CD1 . TRP B 1 254 ? 47.966  -0.672  6.283   1 17.919 ? 246  TRP B CD1 1 
ATOM   5987 C  CD2 . TRP B 1 254 ? 47.879  -0.384  4.056   1 15.918 ? 246  TRP B CD2 1 
ATOM   5988 N  NE1 . TRP B 1 254 ? 46.849  0.072   6.009   1 17.729 ? 246  TRP B NE1 1 
ATOM   5989 C  CE2 . TRP B 1 254 ? 46.778  0.264   4.642   1 15.365 ? 246  TRP B CE2 1 
ATOM   5990 C  CE3 . TRP B 1 254 ? 48.069  -0.322  2.663   1 17.963 ? 246  TRP B CE3 1 
ATOM   5991 C  CZ2 . TRP B 1 254 ? 45.844  0.943   3.883   1 16.162 ? 246  TRP B CZ2 1 
ATOM   5992 C  CZ3 . TRP B 1 254 ? 47.132  0.336   1.897   1 16.026 ? 246  TRP B CZ3 1 
ATOM   5993 C  CH2 . TRP B 1 254 ? 46.052  0.985   2.501   1 16.384 ? 246  TRP B CH2 1 
ATOM   5994 N  N   . CYS B 1 255 ? 49.176  -4.09   6.829   1 12.422 ? 247  CYS B N   1 
ATOM   5995 C  CA  . CYS B 1 255 ? 48.139  -4.665  7.664   1 13.972 ? 247  CYS B CA  1 
ATOM   5996 C  C   . CYS B 1 255 ? 47.132  -3.542  7.932   1 15.99  ? 247  CYS B C   1 
ATOM   5997 O  O   . CYS B 1 255 ? 47.328  -2.748  8.868   1 16.396 ? 247  CYS B O   1 
ATOM   5998 C  CB  . CYS B 1 255 ? 48.666  -5.128  9.044   1 13.871 ? 247  CYS B CB  1 
ATOM   5999 S  SG  . CYS B 1 255 ? 47.459  -6.116  9.972   1 18.296 ? 247  CYS B SG  1 
ATOM   6000 N  N   . ALA B 1 256 ? 46.004  -3.608  7.182   1 14.028 ? 248  ALA B N   1 
ATOM   6001 C  CA  . ALA B 1 256 ? 44.946  -2.619  7.073   1 13.496 ? 248  ALA B CA  1 
ATOM   6002 C  C   . ALA B 1 256 ? 43.669  -3.089  7.753   1 14.175 ? 248  ALA B C   1 
ATOM   6003 O  O   . ALA B 1 256 ? 43.418  -4.291  7.804   1 14.219 ? 248  ALA B O   1 
ATOM   6004 C  CB  . ALA B 1 256 ? 44.664  -2.47   5.565   1 12.049 ? 248  ALA B CB  1 
ATOM   6005 N  N   . PHE B 1 257 ? 42.809  -2.144  8.207   1 14.937 ? 249  PHE B N   1 
ATOM   6006 C  CA  . PHE B 1 257 ? 41.507  -2.486  8.753   1 15.967 ? 249  PHE B CA  1 
ATOM   6007 C  C   . PHE B 1 257 ? 40.536  -2.691  7.586   1 15.445 ? 249  PHE B C   1 
ATOM   6008 O  O   . PHE B 1 257 ? 39.972  -1.738  7.071   1 15.799 ? 249  PHE B O   1 
ATOM   6009 C  CB  . PHE B 1 257 ? 41.213  -1.24   9.618   1 13.629 ? 249  PHE B CB  1 
ATOM   6010 C  CG  . PHE B 1 257 ? 40.125  -1.291  10.661  1 14.758 ? 249  PHE B CG  1 
ATOM   6011 C  CD1 . PHE B 1 257 ? 39.057  -2.193  10.577  1 13.273 ? 249  PHE B CD1 1 
ATOM   6012 C  CD2 . PHE B 1 257 ? 40.199  -0.438  11.775  1 13.58  ? 249  PHE B CD2 1 
ATOM   6013 C  CE1 . PHE B 1 257 ? 38.035  -2.216  11.528  1 14.676 ? 249  PHE B CE1 1 
ATOM   6014 C  CE2 . PHE B 1 257 ? 39.216  -0.491  12.779  1 14.159 ? 249  PHE B CE2 1 
ATOM   6015 C  CZ  . PHE B 1 257 ? 38.147  -1.391  12.677  1 15.217 ? 249  PHE B CZ  1 
ATOM   6016 N  N   . ILE B 1 258 ? 40.3    -3.961  7.222   1 13.436 ? 250  ILE B N   1 
ATOM   6017 C  CA  . ILE B 1 258 ? 39.469  -4.353  6.11    1 12.326 ? 250  ILE B CA  1 
ATOM   6018 C  C   . ILE B 1 258 ? 38.101  -4.727  6.675   1 13.677 ? 250  ILE B C   1 
ATOM   6019 O  O   . ILE B 1 258 ? 37.778  -5.903  6.867   1 15.073 ? 250  ILE B O   1 
ATOM   6020 C  CB  . ILE B 1 258 ? 40.079  -5.449  5.189   1 13.41  ? 250  ILE B CB  1 
ATOM   6021 C  CG1 . ILE B 1 258 ? 41.58   -5.177  4.906   1 13.187 ? 250  ILE B CG1 1 
ATOM   6022 C  CG2 . ILE B 1 258 ? 39.207  -5.517  3.887   1 13.771 ? 250  ILE B CG2 1 
ATOM   6023 C  CD1 . ILE B 1 258 ? 42.293  -6.199  4.013   1 14.362 ? 250  ILE B CD1 1 
ATOM   6024 N  N   . HIS B 1 259 ? 37.281  -3.708  6.913   1 13.769 ? 251  HIS B N   1 
ATOM   6025 C  CA  . HIS B 1 259 ? 36.011  -3.957  7.611   1 13.34  ? 251  HIS B CA  1 
ATOM   6026 C  C   . HIS B 1 259 ? 34.948  -4.577  6.708   1 15.775 ? 251  HIS B C   1 
ATOM   6027 O  O   . HIS B 1 259 ? 34.229  -5.515  7.103   1 15.581 ? 251  HIS B O   1 
ATOM   6028 C  CB  . HIS B 1 259 ? 35.476  -2.671  8.239   1 15.447 ? 251  HIS B CB  1 
ATOM   6029 C  CG  . HIS B 1 259 ? 34.122  -2.845  8.861   1 14.108 ? 251  HIS B CG  1 
ATOM   6030 N  ND1 . HIS B 1 259 ? 34.103  -3.557  10.044  1 18.078 ? 251  HIS B ND1 1 
ATOM   6031 C  CD2 . HIS B 1 259 ? 32.844  -2.497  8.616   1 14.382 ? 251  HIS B CD2 1 
ATOM   6032 C  CE1 . HIS B 1 259 ? 32.87   -3.634  10.514  1 14.788 ? 251  HIS B CE1 1 
ATOM   6033 N  NE2 . HIS B 1 259 ? 32.066  -2.984  9.706   1 15.914 ? 251  HIS B NE2 1 
ATOM   6034 N  N   . ASP B 1 260 ? 34.863  -4.081  5.461   1 15.79  ? 252  ASP B N   1 
ATOM   6035 C  CA  . ASP B 1 260 ? 33.712  -4.43   4.621   1 13.15  ? 252  ASP B CA  1 
ATOM   6036 C  C   . ASP B 1 260 ? 34.257  -4.73   3.22    1 14.313 ? 252  ASP B C   1 
ATOM   6037 O  O   . ASP B 1 260 ? 35.474  -4.607  2.959   1 12.764 ? 252  ASP B O   1 
ATOM   6038 C  CB  . ASP B 1 260 ? 32.67   -3.301  4.613   1 12.261 ? 252  ASP B CB  1 
ATOM   6039 C  CG  . ASP B 1 260 ? 31.247  -3.676  4.164   1 12.022 ? 252  ASP B CG  1 
ATOM   6040 O  OD1 . ASP B 1 260 ? 31.015  -4.874  3.77    1 11.945 ? 252  ASP B OD1 1 
ATOM   6041 O  OD2 . ASP B 1 260 ? 30.3    -2.84   4.309   1 13.142 ? 252  ASP B OD2 1 
ATOM   6042 N  N   . CYS B 1 261 ? 33.316  -5.106  2.336   1 13.896 ? 253  CYS B N   1 
ATOM   6043 C  CA  . CYS B 1 261 ? 33.634  -5.541  0.995   1 14.1   ? 253  CYS B CA  1 
ATOM   6044 C  C   . CYS B 1 261 ? 32.43   -5.326  0.081   1 14.514 ? 253  CYS B C   1 
ATOM   6045 O  O   . CYS B 1 261 ? 31.32   -4.921  0.513   1 13.402 ? 253  CYS B O   1 
ATOM   6046 C  CB  . CYS B 1 261 ? 34.228  -6.973  1.035   1 14.69  ? 253  CYS B CB  1 
ATOM   6047 S  SG  . CYS B 1 261 ? 32.954  -8.137  1.525   1 15.743 ? 253  CYS B SG  1 
ATOM   6048 N  N   . ALA B 1 262 ? 32.648  -5.582  -1.216  1 17.038 ? 254  ALA B N   1 
ATOM   6049 C  CA  . ALA B 1 262 ? 31.511  -5.654  -2.13   1 16.094 ? 254  ALA B CA  1 
ATOM   6050 C  C   . ALA B 1 262 ? 31.578  -6.927  -2.983  1 15.096 ? 254  ALA B C   1 
ATOM   6051 O  O   . ALA B 1 262 ? 32.664  -7.32   -3.428  1 20.632 ? 254  ALA B O   1 
ATOM   6052 C  CB  . ALA B 1 262 ? 31.396  -4.426  -2.997  1 14.891 ? 254  ALA B CB  1 
ATOM   6053 N  N   . LEU B 1 263 ? 30.417  -7.602  -3.159  1 17.237 ? 255  LEU B N   1 
ATOM   6054 C  CA  . LEU B 1 263 ? 30.347  -8.762  -4.033  1 14.161 ? 255  LEU B CA  1 
ATOM   6055 C  C   . LEU B 1 263 ? 29.754  -8.36   -5.369  1 15.36  ? 255  LEU B C   1 
ATOM   6056 O  O   . LEU B 1 263 ? 28.717  -7.698  -5.385  1 15.271 ? 255  LEU B O   1 
ATOM   6057 C  CB  . LEU B 1 263 ? 29.5    -9.83   -3.368  1 14.934 ? 255  LEU B CB  1 
ATOM   6058 C  CG  . LEU B 1 263 ? 29.437  -11.173 -4.09   1 13.756 ? 255  LEU B CG  1 
ATOM   6059 C  CD1 . LEU B 1 263 ? 30.763  -11.889 -4.13   1 14.319 ? 255  LEU B CD1 1 
ATOM   6060 C  CD2 . LEU B 1 263 ? 28.301  -11.979 -3.4    1 19.68  ? 255  LEU B CD2 1 
ATOM   6061 N  N   . THR B 1 264 ? 30.354  -8.877  -6.439  1 18.221 ? 256  THR B N   1 
ATOM   6062 C  CA  . THR B 1 264 ? 29.856  -8.706  -7.802  1 17.391 ? 256  THR B CA  1 
ATOM   6063 C  C   . THR B 1 264 ? 29.834  -10.089 -8.451  1 20.005 ? 256  THR B C   1 
ATOM   6064 O  O   . THR B 1 264 ? 30.241  -11.076 -7.826  1 17.369 ? 256  THR B O   1 
ATOM   6065 C  CB  . THR B 1 264 ? 30.762  -7.764  -8.63   1 19.977 ? 256  THR B CB  1 
ATOM   6066 O  OG1 . THR B 1 264 ? 31.951  -8.47   -9.043  1 18.774 ? 256  THR B OG1 1 
ATOM   6067 C  CG2 . THR B 1 264 ? 31.058  -6.441  -7.939  1 18.186 ? 256  THR B CG2 1 
ATOM   6068 N  N   . PRO B 1 265 ? 29.349  -10.254 -9.734  1 19.632 ? 257  PRO B N   1 
ATOM   6069 C  CA  . PRO B 1 265 ? 29.268  -11.593 -10.281 1 18.194 ? 257  PRO B CA  1 
ATOM   6070 C  C   . PRO B 1 265 ? 30.598  -12.329 -10.368 1 16.432 ? 257  PRO B C   1 
ATOM   6071 O  O   . PRO B 1 265 ? 30.628  -13.568 -10.167 1 20.084 ? 257  PRO B O   1 
ATOM   6072 C  CB  . PRO B 1 265 ? 28.616  -11.408 -11.659 1 21.403 ? 257  PRO B CB  1 
ATOM   6073 C  CG  . PRO B 1 265 ? 27.681  -10.228 -11.37  1 24.848 ? 257  PRO B CG  1 
ATOM   6074 C  CD  . PRO B 1 265 ? 28.593  -9.293  -10.56  1 22.47  ? 257  PRO B CD  1 
ATOM   6075 N  N   . ASN B 1 266 ? 31.659  -11.559 -10.651 1 18.745 ? 258  ASN B N   1 
ATOM   6076 C  CA  . ASN B 1 266 ? 32.994  -12.103 -10.918 1 17.265 ? 258  ASN B CA  1 
ATOM   6077 C  C   . ASN B 1 266 ? 34.04   -11.789 -9.836  1 16.665 ? 258  ASN B C   1 
ATOM   6078 O  O   . ASN B 1 266 ? 35.182  -12.282 -9.949  1 15.928 ? 258  ASN B O   1 
ATOM   6079 C  CB  . ASN B 1 266 ? 33.479  -11.702 -12.3   1 18.283 ? 258  ASN B CB  1 
ATOM   6080 C  CG  . ASN B 1 266 ? 32.513  -12.211 -13.356 1 20.86  ? 258  ASN B CG  1 
ATOM   6081 O  OD1 . ASN B 1 266 ? 32.207  -13.419 -13.402 1 21.621 ? 258  ASN B OD1 1 
ATOM   6082 N  ND2 . ASN B 1 266 ? 31.883  -11.307 -14.103 1 22.45  ? 258  ASN B ND2 1 
ATOM   6083 N  N   . TYR B 1 267 ? 33.709  -10.966 -8.81   1 15.696 ? 259  TYR B N   1 
ATOM   6084 C  CA  . TYR B 1 267 ? 34.767  -10.525 -7.895  1 12.416 ? 259  TYR B CA  1 
ATOM   6085 C  C   . TYR B 1 267 ? 34.227  -10.467 -6.47   1 13.771 ? 259  TYR B C   1 
ATOM   6086 O  O   . TYR B 1 267 ? 33.052  -10.207 -6.297  1 16.615 ? 259  TYR B O   1 
ATOM   6087 C  CB  . TYR B 1 267 ? 35.271  -9.069  -8.113  1 13.427 ? 259  TYR B CB  1 
ATOM   6088 C  CG  . TYR B 1 267 ? 36.007  -8.897  -9.431  1 14.198 ? 259  TYR B CG  1 
ATOM   6089 C  CD1 . TYR B 1 267 ? 35.3    -8.707  -10.639 1 14.992 ? 259  TYR B CD1 1 
ATOM   6090 C  CD2 . TYR B 1 267 ? 37.39   -9.074  -9.476  1 16.112 ? 259  TYR B CD2 1 
ATOM   6091 C  CE1 . TYR B 1 267 ? 36.011  -8.629  -11.834 1 15.148 ? 259  TYR B CE1 1 
ATOM   6092 C  CE2 . TYR B 1 267 ? 38.11   -8.984  -10.667 1 19.357 ? 259  TYR B CE2 1 
ATOM   6093 C  CZ  . TYR B 1 267 ? 37.395  -8.745  -11.843 1 18.367 ? 259  TYR B CZ  1 
ATOM   6094 O  OH  . TYR B 1 267 ? 38.109  -8.683  -13.015 1 19.766 ? 259  TYR B OH  1 
ATOM   6095 N  N   . LEU B 1 268 ? 35.131  -10.691 -5.519  1 12.908 ? 260  LEU B N   1 
ATOM   6096 C  CA  . LEU B 1 268 ? 34.987  -10.109 -4.174  1 13.077 ? 260  LEU B CA  1 
ATOM   6097 C  C   . LEU B 1 268 ? 35.914  -8.893  -4.125  1 14.74  ? 260  LEU B C   1 
ATOM   6098 O  O   . LEU B 1 268 ? 37.136  -9.056  -4.392  1 15.593 ? 260  LEU B O   1 
ATOM   6099 C  CB  . LEU B 1 268 ? 35.342  -11.051 -3.019  1 11.015 ? 260  LEU B CB  1 
ATOM   6100 C  CG  . LEU B 1 268 ? 35.05   -10.467 -1.618  1 9.038  ? 260  LEU B CG  1 
ATOM   6101 C  CD1 . LEU B 1 268 ? 33.558  -10.342 -1.495  1 13.625 ? 260  LEU B CD1 1 
ATOM   6102 C  CD2 . LEU B 1 268 ? 35.596  -11.531 -0.644  1 9.348  ? 260  LEU B CD2 1 
ATOM   6103 N  N   . VAL B 1 269 ? 35.373  -7.729  -3.709  1 13.942 ? 261  VAL B N   1 
ATOM   6104 C  CA  . VAL B 1 269 ? 36.273  -6.571  -3.626  1 14.588 ? 261  VAL B CA  1 
ATOM   6105 C  C   . VAL B 1 269 ? 36.449  -6.12   -2.163  1 14.419 ? 261  VAL B C   1 
ATOM   6106 O  O   . VAL B 1 269 ? 35.473  -5.731  -1.558  1 15.943 ? 261  VAL B O   1 
ATOM   6107 C  CB  . VAL B 1 269 ? 35.822  -5.411  -4.496  1 14.691 ? 261  VAL B CB  1 
ATOM   6108 C  CG1 . VAL B 1 269 ? 36.922  -4.316  -4.54   1 13.059 ? 261  VAL B CG1 1 
ATOM   6109 C  CG2 . VAL B 1 269 ? 35.438  -5.885  -5.92   1 14.413 ? 261  VAL B CG2 1 
ATOM   6110 N  N   . LEU B 1 270 ? 37.673  -6.15   -1.662  1 15.433 ? 262  LEU B N   1 
ATOM   6111 C  CA  . LEU B 1 270 ? 37.967  -5.762  -0.262  1 16.009 ? 262  LEU B CA  1 
ATOM   6112 C  C   . LEU B 1 270 ? 38.138  -4.264  -0.162  1 16.238 ? 262  LEU B C   1 
ATOM   6113 O  O   . LEU B 1 270 ? 38.877  -3.703  -0.938  1 15.532 ? 262  LEU B O   1 
ATOM   6114 C  CB  . LEU B 1 270 ? 39.223  -6.46   0.214   1 16.883 ? 262  LEU B CB  1 
ATOM   6115 C  CG  . LEU B 1 270 ? 39.202  -7.995  0.159   1 18.64  ? 262  LEU B CG  1 
ATOM   6116 C  CD1 . LEU B 1 270 ? 40.375  -8.584  0.888   1 14.625 ? 262  LEU B CD1 1 
ATOM   6117 C  CD2 . LEU B 1 270 ? 37.878  -8.678  0.49    1 16.394 ? 262  LEU B CD2 1 
ATOM   6118 N  N   . MET B 1 271 ? 37.624  -3.622  0.894   1 16.028 ? 263  MET B N   1 
ATOM   6119 C  CA  . MET B 1 271 ? 37.79   -2.193  1.049   1 13.774 ? 263  MET B CA  1 
ATOM   6120 C  C   . MET B 1 271 ? 38.734  -1.923  2.222   1 13.012 ? 263  MET B C   1 
ATOM   6121 O  O   . MET B 1 271 ? 38.402  -2.299  3.334   1 12.779 ? 263  MET B O   1 
ATOM   6122 C  CB  . MET B 1 271 ? 36.378  -1.608  1.226   1 13.699 ? 263  MET B CB  1 
ATOM   6123 C  CG  . MET B 1 271 ? 36.306  -0.088  1.454   1 15.672 ? 263  MET B CG  1 
ATOM   6124 S  SD  . MET B 1 271 ? 34.625  0.474   1.191   1 18.124 ? 263  MET B SD  1 
ATOM   6125 C  CE  . MET B 1 271 ? 33.858  -0.048  2.751   1 16.101 ? 263  MET B CE  1 
ATOM   6126 N  N   . LEU B 1 272 ? 39.894  -1.281  1.96    1 13.177 ? 264  LEU B N   1 
ATOM   6127 C  CA  . LEU B 1 272 ? 40.901  -1.035  2.989   1 13.389 ? 264  LEU B CA  1 
ATOM   6128 C  C   . LEU B 1 272 ? 40.692  0.345   3.608   1 13.826 ? 264  LEU B C   1 
ATOM   6129 O  O   . LEU B 1 272 ? 40.787  1.352   2.872   1 16.992 ? 264  LEU B O   1 
ATOM   6130 C  CB  . LEU B 1 272 ? 42.356  -1.203  2.518   1 12.91  ? 264  LEU B CB  1 
ATOM   6131 C  CG  . LEU B 1 272 ? 42.863  -2.644  2.375   1 15.246 ? 264  LEU B CG  1 
ATOM   6132 C  CD1 . LEU B 1 272 ? 42.056  -3.496  1.4     1 15.668 ? 264  LEU B CD1 1 
ATOM   6133 C  CD2 . LEU B 1 272 ? 44.354  -2.517  1.951   1 15.209 ? 264  LEU B CD2 1 
ATOM   6134 N  N   . TRP B 1 273 ? 40.585  0.386   4.967   1 12.014 ? 265  TRP B N   1 
ATOM   6135 C  CA  . TRP B 1 273 ? 40.54   1.683   5.64    1 12.731 ? 265  TRP B CA  1 
ATOM   6136 C  C   . TRP B 1 273 ? 41.968  2.127   5.9     1 14.39  ? 265  TRP B C   1 
ATOM   6137 O  O   . TRP B 1 273 ? 42.839  1.275   6.068   1 14.588 ? 265  TRP B O   1 
ATOM   6138 C  CB  . TRP B 1 273 ? 39.783  1.6     6.991   1 13.112 ? 265  TRP B CB  1 
ATOM   6139 C  CG  . TRP B 1 273 ? 38.285  1.349   6.899   1 14.702 ? 265  TRP B CG  1 
ATOM   6140 C  CD1 . TRP B 1 273 ? 37.474  1.268   5.807   1 15.998 ? 265  TRP B CD1 1 
ATOM   6141 C  CD2 . TRP B 1 273 ? 37.441  1.094   8.036   1 14.062 ? 265  TRP B CD2 1 
ATOM   6142 N  NE1 . TRP B 1 273 ? 36.168  1.02    6.181   1 15.004 ? 265  TRP B NE1 1 
ATOM   6143 C  CE2 . TRP B 1 273 ? 36.127  0.92    7.556   1 14.208 ? 265  TRP B CE2 1 
ATOM   6144 C  CE3 . TRP B 1 273 ? 37.695  1.057   9.423   1 12.749 ? 265  TRP B CE3 1 
ATOM   6145 C  CZ2 . TRP B 1 273 ? 35.05   0.647   8.413   1 13.828 ? 265  TRP B CZ2 1 
ATOM   6146 C  CZ3 . TRP B 1 273 ? 36.625  0.8     10.273  1 11.851 ? 265  TRP B CZ3 1 
ATOM   6147 C  CH2 . TRP B 1 273 ? 35.331  0.573   9.781   1 13.314 ? 265  TRP B CH2 1 
ATOM   6148 N  N   . PRO B 1 274 ? 42.263  3.448   6.062   1 14.235 ? 266  PRO B N   1 
ATOM   6149 C  CA  . PRO B 1 274 ? 43.629  3.896   6.318   1 16.013 ? 266  PRO B CA  1 
ATOM   6150 C  C   . PRO B 1 274 ? 43.986  3.844   7.805   1 16.317 ? 266  PRO B C   1 
ATOM   6151 O  O   . PRO B 1 274 ? 44.301  4.866   8.388   1 15.481 ? 266  PRO B O   1 
ATOM   6152 C  CB  . PRO B 1 274 ? 43.629  5.312   5.759   1 15.233 ? 266  PRO B CB  1 
ATOM   6153 C  CG  . PRO B 1 274 ? 42.197  5.784   6.056   1 16.512 ? 266  PRO B CG  1 
ATOM   6154 C  CD  . PRO B 1 274 ? 41.336  4.568   5.854   1 13.971 ? 266  PRO B CD  1 
ATOM   6155 N  N   . PHE B 1 275 ? 43.911  2.622   8.362   1 16.415 ? 267  PHE B N   1 
ATOM   6156 C  CA  . PHE B 1 275 ? 44.485  2.304   9.66    1 14.818 ? 267  PHE B CA  1 
ATOM   6157 C  C   . PHE B 1 275 ? 45.574  1.289   9.37    1 15.955 ? 267  PHE B C   1 
ATOM   6158 O  O   . PHE B 1 275 ? 45.433  0.499   8.454   1 19.59  ? 267  PHE B O   1 
ATOM   6159 C  CB  . PHE B 1 275 ? 43.436  1.732   10.64   1 14.161 ? 267  PHE B CB  1 
ATOM   6160 C  CG  . PHE B 1 275 ? 42.349  2.719   11.042  1 15.377 ? 267  PHE B CG  1 
ATOM   6161 C  CD1 . PHE B 1 275 ? 41.249  2.951   10.197  1 13.121 ? 267  PHE B CD1 1 
ATOM   6162 C  CD2 . PHE B 1 275 ? 42.427  3.419   12.271  1 15.23  ? 267  PHE B CD2 1 
ATOM   6163 C  CE1 . PHE B 1 275 ? 40.213  3.845   10.538  1 17.452 ? 267  PHE B CE1 1 
ATOM   6164 C  CE2 . PHE B 1 275 ? 41.389  4.298   12.619  1 17.841 ? 267  PHE B CE2 1 
ATOM   6165 C  CZ  . PHE B 1 275 ? 40.279  4.533   11.75   1 15.944 ? 267  PHE B CZ  1 
ATOM   6166 N  N   . GLU B 1 276 ? 46.631  1.285   10.18   1 16.039 ? 268  GLU B N   1 
ATOM   6167 C  CA  . GLU B 1 276 ? 47.619  0.232   10.101  1 16.562 ? 268  GLU B CA  1 
ATOM   6168 C  C   . GLU B 1 276 ? 47.799  -0.303  11.513  1 16.593 ? 268  GLU B C   1 
ATOM   6169 O  O   . GLU B 1 276 ? 47.646  0.469   12.475  1 16.609 ? 268  GLU B O   1 
ATOM   6170 C  CB  . GLU B 1 276 ? 48.956  0.831   9.636   1 17.489 ? 268  GLU B CB  1 
ATOM   6171 C  CG  . GLU B 1 276 ? 50.03   -0.227  9.352   1 18.928 ? 268  GLU B CG  1 
ATOM   6172 C  CD  . GLU B 1 276 ? 51.186  0.217   8.463   1 20.557 ? 268  GLU B CD  1 
ATOM   6173 O  OE1 . GLU B 1 276 ? 51.266  1.41    8.08    1 26.053 ? 268  GLU B OE1 1 
ATOM   6174 O  OE2 . GLU B 1 276 ? 51.999  -0.676  8.162   1 19.531 ? 268  GLU B OE2 1 
ATOM   6175 N  N   . ALA B 1 277 ? 48.013  -1.627  11.6    1 17.925 ? 269  ALA B N   1 
ATOM   6176 C  CA  . ALA B 1 277 ? 48.309  -2.264  12.859  1 17.211 ? 269  ALA B CA  1 
ATOM   6177 C  C   . ALA B 1 277 ? 49.822  -2.306  13.068  1 20.439 ? 269  ALA B C   1 
ATOM   6178 O  O   . ALA B 1 277 ? 50.594  -2.478  12.121  1 24.103 ? 269  ALA B O   1 
ATOM   6179 C  CB  . ALA B 1 277 ? 47.735  -3.685  12.852  1 16.989 ? 269  ALA B CB  1 
ATOM   6180 N  N   . ASN B 1 278 ? 50.234  -2.223  14.343  1 18.419 ? 270  ASN B N   1 
ATOM   6181 C  CA  . ASN B 1 278 ? 51.641  -2.328  14.662  1 19.818 ? 270  ASN B CA  1 
ATOM   6182 C  C   . ASN B 1 278 ? 51.794  -3.127  15.94   1 16.522 ? 270  ASN B C   1 
ATOM   6183 O  O   . ASN B 1 278 ? 51.354  -2.666  16.99   1 20.71  ? 270  ASN B O   1 
ATOM   6184 C  CB  . ASN B 1 278 ? 52.217  -0.921  14.841  1 23.361 ? 270  ASN B CB  1 
ATOM   6185 C  CG  . ASN B 1 278 ? 53.705  -0.95   15.11   1 25.955 ? 270  ASN B CG  1 
ATOM   6186 O  OD1 . ASN B 1 278 ? 54.115  -1.046  16.256  1 22.054 ? 270  ASN B OD1 1 
ATOM   6187 N  ND2 . ASN B 1 278 ? 54.53   -0.853  14.077  1 31.167 ? 270  ASN B ND2 1 
ATOM   6188 N  N   . LEU B 1 279 ? 52.535  -4.255  15.833  1 17.519 ? 271  LEU B N   1 
ATOM   6189 C  CA  . LEU B 1 279 ? 52.733  -5.152  16.974  1 14.382 ? 271  LEU B CA  1 
ATOM   6190 C  C   . LEU B 1 279 ? 53.509  -4.471  18.068  1 16.788 ? 271  LEU B C   1 
ATOM   6191 O  O   . LEU B 1 279 ? 53.193  -4.682  19.259  1 16.976 ? 271  LEU B O   1 
ATOM   6192 C  CB  . LEU B 1 279 ? 53.49   -6.415  16.488  1 16.301 ? 271  LEU B CB  1 
ATOM   6193 C  CG  . LEU B 1 279 ? 53.451  -7.654  17.389  1 16.576 ? 271  LEU B CG  1 
ATOM   6194 C  CD1 . LEU B 1 279 ? 52.023  -8.259  17.609  1 17.509 ? 271  LEU B CD1 1 
ATOM   6195 C  CD2 . LEU B 1 279 ? 54.265  -8.786  16.707  1 16.784 ? 271  LEU B CD2 1 
ATOM   6196 N  N   . GLU B 1 280 ? 54.566  -3.694  17.678  1 20.727 ? 272  GLU B N   1 
ATOM   6197 C  CA  . GLU B 1 280 ? 55.409  -3.036  18.671  1 25.898 ? 272  GLU B CA  1 
ATOM   6198 C  C   . GLU B 1 280 ? 54.576  -2.132  19.566  1 23.537 ? 272  GLU B C   1 
ATOM   6199 O  O   . GLU B 1 280 ? 54.669  -2.217  20.801  1 23.999 ? 272  GLU B O   1 
ATOM   6200 C  CB  . GLU B 1 280 ? 56.643  -2.319  18.095  1 30.972 ? 272  GLU B CB  1 
ATOM   6201 C  CG  . GLU B 1 280 ? 57.838  -3.248  17.888  1 38.939 ? 272  GLU B CG  1 
ATOM   6202 C  CD  . GLU B 1 280 ? 58.209  -3.983  19.18   1 54.625 ? 272  GLU B CD  1 
ATOM   6203 O  OE1 . GLU B 1 280 ? 58.579  -3.342  20.189  1 53.043 ? 272  GLU B OE1 1 
ATOM   6204 O  OE2 . GLU B 1 280 ? 58.06   -5.224  19.212  1 57.767 ? 272  GLU B OE2 1 
ATOM   6205 N  N   . ARG B 1 281 ? 53.765  -1.282  18.91   1 23.946 ? 273  ARG B N   1 
ATOM   6206 C  CA  . ARG B 1 281 ? 52.805  -0.432  19.607  1 24.197 ? 273  ARG B CA  1 
ATOM   6207 C  C   . ARG B 1 281 ? 51.864  -1.255  20.502  1 21.45  ? 273  ARG B C   1 
ATOM   6208 O  O   . ARG B 1 281 ? 51.633  -0.865  21.652  1 20.455 ? 273  ARG B O   1 
ATOM   6209 C  CB  . ARG B 1 281 ? 51.997  0.378   18.586  1 20.254 ? 273  ARG B CB  1 
ATOM   6210 C  CG  . ARG B 1 281 ? 51.018  1.322   19.288  1 23.977 ? 273  ARG B CG  1 
ATOM   6211 C  CD  . ARG B 1 281 ? 50.232  2.18    18.32   1 21.63  ? 273  ARG B CD  1 
ATOM   6212 N  NE  . ARG B 1 281 ? 49.411  1.415   17.365  1 18.528 ? 273  ARG B NE  1 
ATOM   6213 C  CZ  . ARG B 1 281 ? 49.607  1.475   16.04   1 19.857 ? 273  ARG B CZ  1 
ATOM   6214 N  NH1 . ARG B 1 281 ? 50.504  2.321   15.547  1 19.547 ? 273  ARG B NH1 1 
ATOM   6215 N  NH2 . ARG B 1 281 ? 48.921  0.712   15.22   1 20.427 ? 273  ARG B NH2 1 
ATOM   6216 N  N   . MET B 1 282 ? 51.37   -2.414  20.021  1 18.348 ? 274  MET B N   1 
ATOM   6217 C  CA  . MET B 1 282 ? 50.491  -3.226  20.862  1 14.789 ? 274  MET B CA  1 
ATOM   6218 C  C   . MET B 1 282 ? 51.255  -3.738  22.076  1 15.587 ? 274  MET B C   1 
ATOM   6219 O  O   . MET B 1 282 ? 50.75   -3.649  23.192  1 16.165 ? 274  MET B O   1 
ATOM   6220 C  CB  . MET B 1 282 ? 49.887  -4.393  20.064  1 18.316 ? 274  MET B CB  1 
ATOM   6221 C  CG  . MET B 1 282 ? 48.822  -3.894  19.041  1 21.346 ? 274  MET B CG  1 
ATOM   6222 S  SD  . MET B 1 282 ? 48.054  -5.343  18.267  1 18.941 ? 274  MET B SD  1 
ATOM   6223 C  CE  . MET B 1 282 ? 48.344  -5.03   16.512  1 14.964 ? 274  MET B CE  1 
ATOM   6224 N  N   . LYS B 1 283 ? 52.499  -4.223  21.842  1 17.694 ? 275  LYS B N   1 
ATOM   6225 C  CA  . LYS B 1 283 ? 53.241  -4.785  22.954  1 19.798 ? 275  LYS B CA  1 
ATOM   6226 C  C   . LYS B 1 283 ? 53.502  -3.701  24.003  1 22.581 ? 275  LYS B C   1 
ATOM   6227 O  O   . LYS B 1 283 ? 53.524  -3.995  25.188  1 26.495 ? 275  LYS B O   1 
ATOM   6228 C  CB  . LYS B 1 283 ? 54.532  -5.406  22.413  1 20.546 ? 275  LYS B CB  1 
ATOM   6229 C  CG  . LYS B 1 283 ? 54.292  -6.82   21.929  1 18.758 ? 275  LYS B CG  1 
ATOM   6230 C  CD  . LYS B 1 283 ? 55.436  -7.137  20.963  1 20.39  ? 275  LYS B CD  1 
ATOM   6231 C  CE  . LYS B 1 283 ? 55.425  -8.581  20.56   1 23.076 ? 275  LYS B CE  1 
ATOM   6232 N  NZ  . LYS B 1 283 ? 56.698  -8.969  19.978  1 22.067 ? 275  LYS B NZ  1 
ATOM   6233 N  N   . ALA B 1 284 ? 53.65   -2.456  23.557  1 24.466 ? 276  ALA B N   1 
ATOM   6234 C  CA  . ALA B 1 284 ? 53.862  -1.301  24.431  1 28.609 ? 276  ALA B CA  1 
ATOM   6235 C  C   . ALA B 1 284 ? 52.585  -0.828  25.138  1 27.139 ? 276  ALA B C   1 
ATOM   6236 O  O   . ALA B 1 284 ? 52.652  0.112   25.917  1 23.921 ? 276  ALA B O   1 
ATOM   6237 C  CB  . ALA B 1 284 ? 54.523  -0.171  23.645  1 32.583 ? 276  ALA B CB  1 
ATOM   6238 N  N   . GLY B 1 285 ? 51.448  -1.494  24.91   1 24.625 ? 277  GLY B N   1 
ATOM   6239 C  CA  . GLY B 1 285 ? 50.189  -1.222  25.607  1 23.944 ? 277  GLY B CA  1 
ATOM   6240 C  C   . GLY B 1 285 ? 49.328  -0.188  24.885  1 25.865 ? 277  GLY B C   1 
ATOM   6241 O  O   . GLY B 1 285 ? 48.394  0.368   25.469  1 23.274 ? 277  GLY B O   1 
ATOM   6242 N  N   . GLY B 1 286 ? 49.622  0.012   23.596  1 20.363 ? 278  GLY B N   1 
ATOM   6243 C  CA  . GLY B 1 286 ? 48.945  1.002   22.778  1 21.475 ? 278  GLY B CA  1 
ATOM   6244 C  C   . GLY B 1 286 ? 47.825  0.328   21.984  1 18.846 ? 278  GLY B C   1 
ATOM   6245 O  O   . GLY B 1 286 ? 47.717  -0.892  22.037  1 18.504 ? 278  GLY B O   1 
ATOM   6246 N  N   . HIS B 1 287 ? 47.012  1.13    21.262  1 18.528 ? 279  HIS B N   1 
ATOM   6247 C  CA  . HIS B 1 287 ? 45.942  0.588   20.435  1 21.857 ? 279  HIS B CA  1 
ATOM   6248 C  C   . HIS B 1 287 ? 46.443  -0.263  19.248  1 23.066 ? 279  HIS B C   1 
ATOM   6249 O  O   . HIS B 1 287 ? 47.537  -0.05   18.694  1 20.957 ? 279  HIS B O   1 
ATOM   6250 C  CB  . HIS B 1 287 ? 45.063  1.728   19.926  1 22.261 ? 279  HIS B CB  1 
ATOM   6251 C  CG  . HIS B 1 287 ? 44.066  2.21    20.922  1 21.834 ? 279  HIS B CG  1 
ATOM   6252 N  ND1 . HIS B 1 287 ? 43.09   1.424   21.518  1 20.558 ? 279  HIS B ND1 1 
ATOM   6253 C  CD2 . HIS B 1 287 ? 43.885  3.465   21.395  1 19.594 ? 279  HIS B CD2 1 
ATOM   6254 C  CE1 . HIS B 1 287 ? 42.342  2.205   22.33   1 17.957 ? 279  HIS B CE1 1 
ATOM   6255 N  NE2 . HIS B 1 287 ? 42.781  3.442   22.221  1 17.878 ? 279  HIS B NE2 1 
ATOM   6256 N  N   . HIS B 1 288 ? 45.575  -1.201  18.826  1 16.826 ? 280  HIS B N   1 
ATOM   6257 C  CA  . HIS B 1 288 ? 45.844  -2.074  17.681  1 15.192 ? 280  HIS B CA  1 
ATOM   6258 C  C   . HIS B 1 288 ? 46.008  -1.258  16.387  1 14.877 ? 280  HIS B C   1 
ATOM   6259 O  O   . HIS B 1 288 ? 46.987  -1.445  15.667  1 16.612 ? 280  HIS B O   1 
ATOM   6260 C  CB  . HIS B 1 288 ? 44.7    -3.063  17.504  1 13.014 ? 280  HIS B CB  1 
ATOM   6261 C  CG  . HIS B 1 288 ? 44.864  -4.122  16.443  1 13.338 ? 280  HIS B CG  1 
ATOM   6262 N  ND1 . HIS B 1 288 ? 45.016  -5.447  16.776  1 13.373 ? 280  HIS B ND1 1 
ATOM   6263 C  CD2 . HIS B 1 288 ? 44.844  -4.101  15.06   1 13.953 ? 280  HIS B CD2 1 
ATOM   6264 C  CE1 . HIS B 1 288 ? 45.13   -6.186  15.68   1 14.693 ? 280  HIS B CE1 1 
ATOM   6265 N  NE2 . HIS B 1 288 ? 45.018  -5.386  14.612  1 14.771 ? 280  HIS B NE2 1 
ATOM   6266 N  N   . TRP B 1 289 ? 45.16   -0.276  16.205  1 13.946 ? 281  TRP B N   1 
ATOM   6267 C  CA  . TRP B 1 289 ? 45.022  0.483   14.969  1 16.258 ? 281  TRP B CA  1 
ATOM   6268 C  C   . TRP B 1 289 ? 45.475  1.905   15.249  1 16.388 ? 281  TRP B C   1 
ATOM   6269 O  O   . TRP B 1 289 ? 45.195  2.394   16.336  1 16.054 ? 281  TRP B O   1 
ATOM   6270 C  CB  . TRP B 1 289 ? 43.549  0.487   14.498  1 15.642 ? 281  TRP B CB  1 
ATOM   6271 C  CG  . TRP B 1 289 ? 43.006  -0.843  14.06   1 16.087 ? 281  TRP B CG  1 
ATOM   6272 C  CD1 . TRP B 1 289 ? 41.961  -1.531  14.611  1 16.655 ? 281  TRP B CD1 1 
ATOM   6273 C  CD2 . TRP B 1 289 ? 43.453  -1.635  12.934  1 16.462 ? 281  TRP B CD2 1 
ATOM   6274 N  NE1 . TRP B 1 289 ? 41.735  -2.71   13.942  1 14.256 ? 281  TRP B NE1 1 
ATOM   6275 C  CE2 . TRP B 1 289 ? 42.618  -2.78   12.888  1 17.661 ? 281  TRP B CE2 1 
ATOM   6276 C  CE3 . TRP B 1 289 ? 44.483  -1.5    11.98   1 17.401 ? 281  TRP B CE3 1 
ATOM   6277 C  CZ2 . TRP B 1 289 ? 42.801  -3.792  11.918  1 16.894 ? 281  TRP B CZ2 1 
ATOM   6278 C  CZ3 . TRP B 1 289 ? 44.669  -2.489  11.023  1 17.726 ? 281  TRP B CZ3 1 
ATOM   6279 C  CH2 . TRP B 1 289 ? 43.836  -3.636  11.014  1 20.032 ? 281  TRP B CH2 1 
ATOM   6280 N  N   . ALA B 1 290 ? 46.037  2.572   14.221  1 17.184 ? 282  ALA B N   1 
ATOM   6281 C  CA  . ALA B 1 290 ? 46.285  4.017   14.211  1 16.274 ? 282  ALA B CA  1 
ATOM   6282 C  C   . ALA B 1 290 ? 45.935  4.522   12.825  1 16.649 ? 282  ALA B C   1 
ATOM   6283 O  O   . ALA B 1 290 ? 46.332  3.943   11.798  1 13.533 ? 282  ALA B O   1 
ATOM   6284 C  CB  . ALA B 1 290 ? 47.774  4.281   14.55   1 20.505 ? 282  ALA B CB  1 
ATOM   6285 N  N   . TYR B 1 291 ? 45.122  5.583   12.794  1 17.575 ? 283  TYR B N   1 
ATOM   6286 C  CA  . TYR B 1 291 ? 44.716  6.186   11.53   1 18.797 ? 283  TYR B CA  1 
ATOM   6287 C  C   . TYR B 1 291 ? 45.978  6.789   10.908  1 19.069 ? 283  TYR B C   1 
ATOM   6288 O  O   . TYR B 1 291 ? 46.854  7.276   11.628  1 19.266 ? 283  TYR B O   1 
ATOM   6289 C  CB  . TYR B 1 291 ? 43.67   7.302   11.764  1 15.533 ? 283  TYR B CB  1 
ATOM   6290 C  CG  . TYR B 1 291 ? 43.037  7.852   10.496  1 19.298 ? 283  TYR B CG  1 
ATOM   6291 C  CD1 . TYR B 1 291 ? 43.598  8.907   9.763   1 20.984 ? 283  TYR B CD1 1 
ATOM   6292 C  CD2 . TYR B 1 291 ? 41.858  7.272   9.993   1 18.971 ? 283  TYR B CD2 1 
ATOM   6293 C  CE1 . TYR B 1 291 ? 42.994  9.38    8.602   1 20.041 ? 283  TYR B CE1 1 
ATOM   6294 C  CE2 . TYR B 1 291 ? 41.225  7.772   8.849   1 22.19  ? 283  TYR B CE2 1 
ATOM   6295 C  CZ  . TYR B 1 291 ? 41.787  8.832   8.157   1 21.768 ? 283  TYR B CZ  1 
ATOM   6296 O  OH  . TYR B 1 291 ? 41.199  9.238   6.981   1 25.758 ? 283  TYR B OH  1 
ATOM   6297 N  N   . ASP B 1 292 ? 46.059  6.744   9.574   1 14.747 ? 284  ASP B N   1 
ATOM   6298 C  CA  . ASP B 1 292 ? 47.193  7.302   8.88    1 18.56  ? 284  ASP B CA  1 
ATOM   6299 C  C   . ASP B 1 292 ? 46.688  8.116   7.707   1 18.322 ? 284  ASP B C   1 
ATOM   6300 O  O   . ASP B 1 292 ? 46.248  7.516   6.707   1 18.144 ? 284  ASP B O   1 
ATOM   6301 C  CB  . ASP B 1 292 ? 48.021  6.182   8.266   1 20.727 ? 284  ASP B CB  1 
ATOM   6302 C  CG  . ASP B 1 292 ? 49.342  6.527   7.595   1 18.343 ? 284  ASP B CG  1 
ATOM   6303 O  OD1 . ASP B 1 292 ? 49.633  7.75    7.423   1 22.875 ? 284  ASP B OD1 1 
ATOM   6304 O  OD2 . ASP B 1 292 ? 50.104  5.552   7.352   1 18.713 ? 284  ASP B OD2 1 
ATOM   6305 N  N   . TYR B 1 293 ? 46.837  9.455   7.815   1 15.77  ? 285  TYR B N   1 
ATOM   6306 C  CA  . TYR B 1 293 ? 46.46   10.321  6.685   1 18.415 ? 285  TYR B CA  1 
ATOM   6307 C  C   . TYR B 1 293 ? 47.194  10.002  5.378   1 16.42  ? 285  TYR B C   1 
ATOM   6308 O  O   . TYR B 1 293 ? 46.725  10.398  4.3     1 19.444 ? 285  TYR B O   1 
ATOM   6309 C  CB  . TYR B 1 293 ? 46.614  11.805  7.057   1 20.608 ? 285  TYR B CB  1 
ATOM   6310 C  CG  . TYR B 1 293 ? 45.526  12.206  8.037   1 22.547 ? 285  TYR B CG  1 
ATOM   6311 C  CD1 . TYR B 1 293 ? 44.262  12.644  7.584   1 28.042 ? 285  TYR B CD1 1 
ATOM   6312 C  CD2 . TYR B 1 293 ? 45.762  12.173  9.419   1 25.515 ? 285  TYR B CD2 1 
ATOM   6313 C  CE1 . TYR B 1 293 ? 43.259  13.041  8.479   1 29.256 ? 285  TYR B CE1 1 
ATOM   6314 C  CE2 . TYR B 1 293 ? 44.791  12.605  10.318  1 24.765 ? 285  TYR B CE2 1 
ATOM   6315 C  CZ  . TYR B 1 293 ? 43.54   13.012  9.85    1 29.109 ? 285  TYR B CZ  1 
ATOM   6316 O  OH  . TYR B 1 293 ? 42.611  13.352  10.781  1 37.121 ? 285  TYR B OH  1 
ATOM   6317 N  N   . THR B 1 294 ? 48.381  9.384   5.448   1 18.774 ? 286  THR B N   1 
ATOM   6318 C  CA  . THR B 1 294 ? 49.188  9.097   4.256   1 22.692 ? 286  THR B CA  1 
ATOM   6319 C  C   . THR B 1 294 ? 48.693  7.873   3.475   1 24.633 ? 286  THR B C   1 
ATOM   6320 O  O   . THR B 1 294 ? 48.987  7.749   2.284   1 21.468 ? 286  THR B O   1 
ATOM   6321 C  CB  . THR B 1 294 ? 50.711  9.084   4.496   1 26.617 ? 286  THR B CB  1 
ATOM   6322 O  OG1 . THR B 1 294 ? 51.07   7.91    5.219   1 26.8   ? 286  THR B OG1 1 
ATOM   6323 C  CG2 . THR B 1 294 ? 51.205  10.362  5.145   1 23.209 ? 286  THR B CG2 1 
ATOM   6324 N  N   . LYS B 1 295 ? 47.875  7.015   4.104   1 22.92  ? 287  LYS B N   1 
ATOM   6325 C  CA  . LYS B 1 295 ? 47.346  5.843   3.409   1 23.223 ? 287  LYS B CA  1 
ATOM   6326 C  C   . LYS B 1 295 ? 46.209  6.187   2.48    1 16.804 ? 287  LYS B C   1 
ATOM   6327 O  O   . LYS B 1 295 ? 45.219  6.742   2.937   1 17.754 ? 287  LYS B O   1 
ATOM   6328 C  CB  . LYS B 1 295 ? 46.895  4.706   4.323   1 21.062 ? 287  LYS B CB  1 
ATOM   6329 C  CG  . LYS B 1 295 ? 48.082  4.053   5.01    1 23.588 ? 287  LYS B CG  1 
ATOM   6330 C  CD  . LYS B 1 295 ? 48.863  3.095   4.119   1 20.496 ? 287  LYS B CD  1 
ATOM   6331 C  CE  . LYS B 1 295 ? 50.1    2.584   4.778   1 27.266 ? 287  LYS B CE  1 
ATOM   6332 N  NZ  . LYS B 1 295 ? 50.799  2.022   3.603   1 33.705 ? 287  LYS B NZ  1 
ATOM   6333 N  N   . PRO B 1 296 ? 46.255  5.842   1.157   1 15.332 ? 288  PRO B N   1 
ATOM   6334 C  CA  . PRO B 1 296 ? 45.076  6.066   0.345   1 14.716 ? 288  PRO B CA  1 
ATOM   6335 C  C   . PRO B 1 296 ? 44.067  4.943   0.57    1 15.221 ? 288  PRO B C   1 
ATOM   6336 O  O   . PRO B 1 296 ? 44.456  3.814   0.906   1 14.869 ? 288  PRO B O   1 
ATOM   6337 C  CB  . PRO B 1 296 ? 45.556  5.9     -1.116  1 13.896 ? 288  PRO B CB  1 
ATOM   6338 C  CG  . PRO B 1 296 ? 46.818  5.097   -0.943  1 16.338 ? 288  PRO B CG  1 
ATOM   6339 C  CD  . PRO B 1 296 ? 47.332  5.16    0.45    1 18.416 ? 288  PRO B CD  1 
ATOM   6340 N  N   . ILE B 1 297 ? 42.781  5.239   0.344   1 14.094 ? 289  ILE B N   1 
ATOM   6341 C  CA  . ILE B 1 297 ? 41.777  4.197   0.255   1 17.397 ? 289  ILE B CA  1 
ATOM   6342 C  C   . ILE B 1 297 ? 42.243  3.217   -0.831  1 20.136 ? 289  ILE B C   1 
ATOM   6343 O  O   . ILE B 1 297 ? 42.606  3.635   -1.946  1 15.139 ? 289  ILE B O   1 
ATOM   6344 C  CB  . ILE B 1 297 ? 40.402  4.84    -0.08   1 17.13  ? 289  ILE B CB  1 
ATOM   6345 C  CG1 . ILE B 1 297 ? 39.888  5.635   1.175   1 19.667 ? 289  ILE B CG1 1 
ATOM   6346 C  CG2 . ILE B 1 297 ? 39.352  3.811   -0.528  1 17.632 ? 289  ILE B CG2 1 
ATOM   6347 C  CD1 . ILE B 1 297 ? 38.808  6.649   0.83    1 23.371 ? 289  ILE B CD1 1 
ATOM   6348 N  N   . THR B 1 298 ? 42.186  1.904   -0.477  1 15.749 ? 290  THR B N   1 
ATOM   6349 C  CA  . THR B 1 298 ? 42.762  0.846   -1.308  1 17.179 ? 290  THR B CA  1 
ATOM   6350 C  C   . THR B 1 298 ? 41.715  -0.282  -1.387  1 17.866 ? 290  THR B C   1 
ATOM   6351 O  O   . THR B 1 298 ? 40.973  -0.5    -0.429  1 17.178 ? 290  THR B O   1 
ATOM   6352 C  CB  . THR B 1 298 ? 44.104  0.439   -0.692  1 16.417 ? 290  THR B CB  1 
ATOM   6353 O  OG1 . THR B 1 298 ? 44.972  1.571   -0.791  1 16.272 ? 290  THR B OG1 1 
ATOM   6354 C  CG2 . THR B 1 298 ? 44.792  -0.709  -1.421  1 18.024 ? 290  THR B CG2 1 
ATOM   6355 N  N   . TRP B 1 299 ? 41.534  -0.836  -2.592  1 16.692 ? 291  TRP B N   1 
ATOM   6356 C  CA  . TRP B 1 299 ? 40.667  -1.967  -2.875  1 15.159 ? 291  TRP B CA  1 
ATOM   6357 C  C   . TRP B 1 299 ? 41.522  -3.157  -3.337  1 17.073 ? 291  TRP B C   1 
ATOM   6358 O  O   . TRP B 1 299 ? 42.488  -2.967  -4.077  1 17.876 ? 291  TRP B O   1 
ATOM   6359 C  CB  . TRP B 1 299 ? 39.671  -1.572  -3.988  1 17.299 ? 291  TRP B CB  1 
ATOM   6360 C  CG  . TRP B 1 299 ? 38.89   -0.313  -3.667  1 17.267 ? 291  TRP B CG  1 
ATOM   6361 C  CD1 . TRP B 1 299 ? 39.294  0.972   -3.886  1 18.828 ? 291  TRP B CD1 1 
ATOM   6362 C  CD2 . TRP B 1 299 ? 37.562  -0.236  -3.11   1 18.154 ? 291  TRP B CD2 1 
ATOM   6363 N  NE1 . TRP B 1 299 ? 38.32   1.853   -3.505  1 16.958 ? 291  TRP B NE1 1 
ATOM   6364 C  CE2 . TRP B 1 299 ? 37.234  1.141   -3.046  1 18.299 ? 291  TRP B CE2 1 
ATOM   6365 C  CE3 . TRP B 1 299 ? 36.615  -1.19   -2.682  1 16.659 ? 291  TRP B CE3 1 
ATOM   6366 C  CZ2 . TRP B 1 299 ? 35.996  1.575   -2.562  1 16.173 ? 291  TRP B CZ2 1 
ATOM   6367 C  CZ3 . TRP B 1 299 ? 35.395  -0.754  -2.209  1 16.412 ? 291  TRP B CZ3 1 
ATOM   6368 C  CH2 . TRP B 1 299 ? 35.066  0.608   -2.186  1 14.824 ? 291  TRP B CH2 1 
ATOM   6369 N  N   . ILE B 1 300 ? 41.131  -4.363  -2.903  1 14.858 ? 292  ILE B N   1 
ATOM   6370 C  CA  . ILE B 1 300 ? 41.683  -5.616  -3.422  1 17.337 ? 292  ILE B CA  1 
ATOM   6371 C  C   . ILE B 1 300 ? 40.604  -6.306  -4.24   1 17.893 ? 292  ILE B C   1 
ATOM   6372 O  O   . ILE B 1 300 ? 39.566  -6.743  -3.681  1 17.501 ? 292  ILE B O   1 
ATOM   6373 C  CB  . ILE B 1 300 ? 42.23   -6.478  -2.265  1 16.226 ? 292  ILE B CB  1 
ATOM   6374 C  CG1 . ILE B 1 300 ? 43.272  -5.726  -1.46   1 15.464 ? 292  ILE B CG1 1 
ATOM   6375 C  CG2 . ILE B 1 300 ? 42.72   -7.839  -2.779  1 15.944 ? 292  ILE B CG2 1 
ATOM   6376 C  CD1 . ILE B 1 300 ? 43.626  -6.373  -0.141  1 15.006 ? 292  ILE B CD1 1 
ATOM   6377 N  N   . THR B 1 301 ? 40.852  -6.458  -5.56   1 16.446 ? 293  THR B N   1 
ATOM   6378 C  CA  . THR B 1 301 ? 39.881  -7.207  -6.346  1 15.628 ? 293  THR B CA  1 
ATOM   6379 C  C   . THR B 1 301 ? 40.389  -8.66   -6.362  1 18.761 ? 293  THR B C   1 
ATOM   6380 O  O   . THR B 1 301 ? 41.573  -8.932  -6.629  1 18.585 ? 293  THR B O   1 
ATOM   6381 C  CB  . THR B 1 301 ? 39.722  -6.674  -7.786  1 17.061 ? 293  THR B CB  1 
ATOM   6382 O  OG1 . THR B 1 301 ? 41.039  -6.528  -8.318  1 14.443 ? 293  THR B OG1 1 
ATOM   6383 C  CG2 . THR B 1 301 ? 39.06   -5.307  -7.813  1 13.363 ? 293  THR B CG2 1 
ATOM   6384 N  N   . ILE B 1 302 ? 39.494  -9.583  -6.031  1 16.05  ? 294  ILE B N   1 
ATOM   6385 C  CA  . ILE B 1 302 ? 39.778  -11.016 -5.966  1 15.254 ? 294  ILE B CA  1 
ATOM   6386 C  C   . ILE B 1 302 ? 38.803  -11.647 -6.945  1 15.943 ? 294  ILE B C   1 
ATOM   6387 O  O   . ILE B 1 302 ? 37.602  -11.785 -6.668  1 13.202 ? 294  ILE B O   1 
ATOM   6388 C  CB  . ILE B 1 302 ? 39.608  -11.618 -4.544  1 14.723 ? 294  ILE B CB  1 
ATOM   6389 C  CG1 . ILE B 1 302 ? 40.394  -10.893 -3.514  1 16.237 ? 294  ILE B CG1 1 
ATOM   6390 C  CG2 . ILE B 1 302 ? 39.98   -13.096 -4.55   1 15.3   ? 294  ILE B CG2 1 
ATOM   6391 C  CD1 . ILE B 1 302 ? 40.053  -11.289 -2.064  1 17.092 ? 294  ILE B CD1 1 
ATOM   6392 N  N   . PRO B 1 303 ? 39.291  -12.075 -8.129  1 17.751 ? 295  PRO B N   1 
ATOM   6393 C  CA  . PRO B 1 303 ? 38.434  -12.856 -9.025  1 19.947 ? 295  PRO B CA  1 
ATOM   6394 C  C   . PRO B 1 303 ? 37.821  -14.064 -8.313  1 18.546 ? 295  PRO B C   1 
ATOM   6395 O  O   . PRO B 1 303 ? 38.562  -14.827 -7.658  1 16.308 ? 295  PRO B O   1 
ATOM   6396 C  CB  . PRO B 1 303 ? 39.451  -13.323 -10.098 1 23.911 ? 295  PRO B CB  1 
ATOM   6397 C  CG  . PRO B 1 303 ? 40.529  -12.242 -10.076 1 23.481 ? 295  PRO B CG  1 
ATOM   6398 C  CD  . PRO B 1 303 ? 40.669  -11.885 -8.614  1 21.385 ? 295  PRO B CD  1 
ATOM   6399 N  N   . ARG B 1 304 ? 36.485  -14.257 -8.44   1 16.548 ? 296  ARG B N   1 
ATOM   6400 C  CA  . ARG B 1 304 ? 35.856  -15.36  -7.714  1 16.309 ? 296  ARG B CA  1 
ATOM   6401 C  C   . ARG B 1 304 ? 36.377  -16.709 -8.234  1 16.514 ? 296  ARG B C   1 
ATOM   6402 O  O   . ARG B 1 304 ? 36.48   -16.93  -9.465  1 16.242 ? 296  ARG B O   1 
ATOM   6403 C  CB  . ARG B 1 304 ? 34.331  -15.314 -7.686  1 17.219 ? 296  ARG B CB  1 
ATOM   6404 C  CG  . ARG B 1 304 ? 33.889  -14.092 -6.879  1 15.852 ? 296  ARG B CG  1 
ATOM   6405 C  CD  . ARG B 1 304 ? 32.456  -13.758 -6.906  1 19.686 ? 296  ARG B CD  1 
ATOM   6406 N  NE  . ARG B 1 304 ? 31.699  -14.907 -6.396  1 17.564 ? 296  ARG B NE  1 
ATOM   6407 C  CZ  . ARG B 1 304 ? 30.374  -14.934 -6.378  1 18.737 ? 296  ARG B CZ  1 
ATOM   6408 N  NH1 . ARG B 1 304 ? 29.739  -13.965 -7.005  1 17.933 ? 296  ARG B NH1 1 
ATOM   6409 N  NH2 . ARG B 1 304 ? 29.743  -15.97  -5.805  1 17.771 ? 296  ARG B NH2 1 
ATOM   6410 N  N   . GLY B 1 305 ? 36.747  -17.56  -7.295  1 14.362 ? 297  GLY B N   1 
ATOM   6411 C  CA  . GLY B 1 305 ? 37.398  -18.846 -7.596  1 17.478 ? 297  GLY B CA  1 
ATOM   6412 C  C   . GLY B 1 305 ? 38.797  -18.775 -8.228  1 22.292 ? 297  GLY B C   1 
ATOM   6413 O  O   . GLY B 1 305 ? 39.229  -19.738 -8.906  1 22.944 ? 297  GLY B O   1 
ATOM   6414 N  N   . ALA B 1 306 ? 39.505  -17.645 -8.067  1 20.55  ? 298  ALA B N   1 
ATOM   6415 C  CA  . ALA B 1 306 ? 40.913  -17.522 -8.44   1 20.577 ? 298  ALA B CA  1 
ATOM   6416 C  C   . ALA B 1 306 ? 41.759  -18.703 -7.975  1 20.534 ? 298  ALA B C   1 
ATOM   6417 O  O   . ALA B 1 306 ? 41.741  -19.096 -6.791  1 22.509 ? 298  ALA B O   1 
ATOM   6418 C  CB  . ALA B 1 306 ? 41.477  -16.216 -7.862  1 16.89  ? 298  ALA B CB  1 
ATOM   6419 N  N   . LYS B 1 307 ? 42.621  -19.16  -8.891  1 19.705 ? 299  LYS B N   1 
ATOM   6420 C  CA  . LYS B 1 307 ? 43.595  -20.228 -8.612  1 20.981 ? 299  LYS B CA  1 
ATOM   6421 C  C   . LYS B 1 307 ? 44.949  -19.741 -8.103  1 23.493 ? 299  LYS B C   1 
ATOM   6422 O  O   . LYS B 1 307 ? 45.743  -20.54  -7.568  1 21.202 ? 299  LYS B O   1 
ATOM   6423 C  CB  . LYS B 1 307 ? 43.702  -21.147 -9.836  1 22.078 ? 299  LYS B CB  1 
ATOM   6424 C  CG  . LYS B 1 307 ? 42.325  -21.824 -10.119 1 20.833 ? 299  LYS B CG  1 
ATOM   6425 C  CD  . LYS B 1 307 ? 41.689  -22.542 -8.919  1 21.509 ? 299  LYS B CD  1 
ATOM   6426 C  CE  . LYS B 1 307 ? 40.595  -23.44  -9.446  1 22.88  ? 299  LYS B CE  1 
ATOM   6427 N  NZ  . LYS B 1 307 ? 39.415  -22.656 -9.916  1 21.833 ? 299  LYS B NZ  1 
ATOM   6428 N  N   . SER B 1 308 ? 45.237  -18.441 -8.29   1 20.273 ? 300  SER B N   1 
ATOM   6429 C  CA  . SER B 1 308 ? 46.502  -17.884 -7.836  1 21.679 ? 300  SER B CA  1 
ATOM   6430 C  C   . SER B 1 308 ? 46.314  -16.477 -7.253  1 18.998 ? 300  SER B C   1 
ATOM   6431 O  O   . SER B 1 308 ? 45.573  -15.705 -7.806  1 21.517 ? 300  SER B O   1 
ATOM   6432 C  CB  . SER B 1 308 ? 47.469  -17.761 -9.042  1 29.036 ? 300  SER B CB  1 
ATOM   6433 O  OG  . SER B 1 308 ? 48.681  -17.118 -8.654  1 25.094 ? 300  SER B OG  1 
ATOM   6434 N  N   . LYS B 1 309 ? 47.105  -16.111 -6.232  1 20.511 ? 301  LYS B N   1 
ATOM   6435 C  CA  . LYS B 1 309 ? 47.119  -14.746 -5.717  1 19.931 ? 301  LYS B CA  1 
ATOM   6436 C  C   . LYS B 1 309 ? 47.649  -13.79  -6.787  1 24.525 ? 301  LYS B C   1 
ATOM   6437 O  O   . LYS B 1 309 ? 47.483  -12.575 -6.691  1 19.577 ? 301  LYS B O   1 
ATOM   6438 C  CB  . LYS B 1 309 ? 47.936  -14.653 -4.428  1 22.743 ? 301  LYS B CB  1 
ATOM   6439 C  CG  . LYS B 1 309 ? 49.458  -14.799 -4.6    1 23.041 ? 301  LYS B CG  1 
ATOM   6440 C  CD  . LYS B 1 309 ? 50.057  -15.082 -3.224  1 26.188 ? 301  LYS B CD  1 
ATOM   6441 C  CE  . LYS B 1 309 ? 51.5    -14.878 -3.283  1 31.755 ? 301  LYS B CE  1 
ATOM   6442 N  NZ  . LYS B 1 309 ? 51.805  -14.786 -1.856  1 48.906 ? 301  LYS B NZ  1 
ATOM   6443 N  N   . ASP B 1 310 ? 48.284  -14.343 -7.847  1 25.383 ? 302  ASP B N   1 
ATOM   6444 C  CA  . ASP B 1 310 ? 48.715  -13.514 -8.975  1 25.657 ? 302  ASP B CA  1 
ATOM   6445 C  C   . ASP B 1 310 ? 47.539  -12.864 -9.695  1 24.653 ? 302  ASP B C   1 
ATOM   6446 O  O   . ASP B 1 310 ? 47.726  -11.86  -10.395 1 24.039 ? 302  ASP B O   1 
ATOM   6447 C  CB  . ASP B 1 310 ? 49.556  -14.291 -9.975  1 26.459 ? 302  ASP B CB  1 
ATOM   6448 C  CG  . ASP B 1 310 ? 50.892  -14.816 -9.476  1 30.223 ? 302  ASP B CG  1 
ATOM   6449 O  OD1 . ASP B 1 310 ? 51.249  -14.529 -8.302  1 27.643 ? 302  ASP B OD1 1 
ATOM   6450 O  OD2 . ASP B 1 310 ? 51.522  -15.583 -10.238 1 33.546 ? 302  ASP B OD2 1 
ATOM   6451 N  N   . GLU B 1 311 ? 46.344  -13.454 -9.564  1 20.96  ? 303  GLU B N   1 
ATOM   6452 C  CA  . GLU B 1 311 ? 45.121  -12.937 -10.163 1 17.802 ? 303  GLU B CA  1 
ATOM   6453 C  C   . GLU B 1 311 ? 44.513  -11.734 -9.413  1 16.532 ? 303  GLU B C   1 
ATOM   6454 O  O   . GLU B 1 311 ? 43.716  -10.99  -9.993  1 16.304 ? 303  GLU B O   1 
ATOM   6455 C  CB  . GLU B 1 311 ? 44.043  -14.023 -10.172 1 17.538 ? 303  GLU B CB  1 
ATOM   6456 C  CG  . GLU B 1 311 ? 44.426  -15.204 -11.072 1 21.16  ? 303  GLU B CG  1 
ATOM   6457 C  CD  . GLU B 1 311 ? 43.304  -16.229 -11.174 1 22.126 ? 303  GLU B CD  1 
ATOM   6458 O  OE1 . GLU B 1 311 ? 42.125  -15.863 -11.524 1 25.415 ? 303  GLU B OE1 1 
ATOM   6459 O  OE2 . GLU B 1 311 ? 43.649  -17.395 -10.853 1 25.718 ? 303  GLU B OE2 1 
ATOM   6460 N  N   . VAL B 1 312 ? 44.892  -11.55  -8.139  1 16.14  ? 304  VAL B N   1 
ATOM   6461 C  CA  . VAL B 1 312 ? 44.393  -10.433 -7.319  1 15.802 ? 304  VAL B CA  1 
ATOM   6462 C  C   . VAL B 1 312 ? 45.158  -9.148  -7.708  1 16.03  ? 304  VAL B C   1 
ATOM   6463 O  O   . VAL B 1 312 ? 46.364  -9.185  -8.019  1 16.502 ? 304  VAL B O   1 
ATOM   6464 C  CB  . VAL B 1 312 ? 44.731  -10.869 -5.871  1 19.096 ? 304  VAL B CB  1 
ATOM   6465 C  CG1 . VAL B 1 312 ? 44.433  -9.775  -4.842  1 23.464 ? 304  VAL B CG1 1 
ATOM   6466 C  CG2 . VAL B 1 312 ? 44.029  -12.159 -5.457  1 21.602 ? 304  VAL B CG2 1 
ATOM   6467 N  N   . LYS B 1 313 ? 44.471  -7.985  -7.604  1 16.317 ? 305  LYS B N   1 
ATOM   6468 C  CA  . LYS B 1 313 ? 44.986  -6.66   -7.934  1 15.907 ? 305  LYS B CA  1 
ATOM   6469 C  C   . LYS B 1 313 ? 44.661  -5.672  -6.814  1 16.001 ? 305  LYS B C   1 
ATOM   6470 O  O   . LYS B 1 313 ? 43.633  -5.825  -6.185  1 16.575 ? 305  LYS B O   1 
ATOM   6471 C  CB  . LYS B 1 313 ? 44.396  -6.197  -9.285  1 17.298 ? 305  LYS B CB  1 
ATOM   6472 C  CG  . LYS B 1 313 ? 45.021  -7.012  -10.463 1 23.365 ? 305  LYS B CG  1 
ATOM   6473 C  CD  . LYS B 1 313 ? 44.464  -6.472  -11.786 1 27.089 ? 305  LYS B CD  1 
ATOM   6474 C  CE  . LYS B 1 313 ? 44.944  -7.225  -13.018 1 35.78  ? 305  LYS B CE  1 
ATOM   6475 N  NZ  . LYS B 1 313 ? 46.402  -7.174  -13.021 1 42.271 ? 305  LYS B NZ  1 
ATOM   6476 N  N   . TYR B 1 314 ? 45.605  -4.748  -6.521  1 19.005 ? 306  TYR B N   1 
ATOM   6477 C  CA  . TYR B 1 314 ? 45.373  -3.599  -5.641  1 19.317 ? 306  TYR B CA  1 
ATOM   6478 C  C   . TYR B 1 314 ? 45.099  -2.338  -6.463  1 21.518 ? 306  TYR B C   1 
ATOM   6479 O  O   . TYR B 1 314 ? 45.855  -2.04   -7.425  1 21.583 ? 306  TYR B O   1 
ATOM   6480 C  CB  . TYR B 1 314 ? 46.56   -3.292  -4.716  1 19.214 ? 306  TYR B CB  1 
ATOM   6481 C  CG  . TYR B 1 314 ? 47.162  -4.456  -3.962  1 18.656 ? 306  TYR B CG  1 
ATOM   6482 C  CD1 . TYR B 1 314 ? 46.366  -5.542  -3.552  1 22.346 ? 306  TYR B CD1 1 
ATOM   6483 C  CD2 . TYR B 1 314 ? 48.508  -4.463  -3.62   1 20.609 ? 306  TYR B CD2 1 
ATOM   6484 C  CE1 . TYR B 1 314 ? 46.905  -6.604  -2.853  1 20.838 ? 306  TYR B CE1 1 
ATOM   6485 C  CE2 . TYR B 1 314 ? 49.061  -5.515  -2.902  1 22.104 ? 306  TYR B CE2 1 
ATOM   6486 C  CZ  . TYR B 1 314 ? 48.256  -6.586  -2.529  1 23.319 ? 306  TYR B CZ  1 
ATOM   6487 O  OH  . TYR B 1 314 ? 48.78   -7.638  -1.83   1 24.473 ? 306  TYR B OH  1 
ATOM   6488 N  N   . TRP B 1 315 ? 44.053  -1.594  -6.033  1 16.343 ? 307  TRP B N   1 
ATOM   6489 C  CA  . TRP B 1 315 ? 43.681  -0.332  -6.64   1 17.63  ? 307  TRP B CA  1 
ATOM   6490 C  C   . TRP B 1 315 ? 43.673  0.741   -5.549  1 18.195 ? 307  TRP B C   1 
ATOM   6491 O  O   . TRP B 1 315 ? 43.299  0.452   -4.407  1 20.3   ? 307  TRP B O   1 
ATOM   6492 C  CB  . TRP B 1 315 ? 42.264  -0.49   -7.184  1 17.816 ? 307  TRP B CB  1 
ATOM   6493 C  CG  . TRP B 1 315 ? 42.133  -1.692  -8.066  1 16.397 ? 307  TRP B CG  1 
ATOM   6494 C  CD1 . TRP B 1 315 ? 41.995  -2.995  -7.67   1 14.882 ? 307  TRP B CD1 1 
ATOM   6495 C  CD2 . TRP B 1 315 ? 42.132  -1.673  -9.516  1 16.11  ? 307  TRP B CD2 1 
ATOM   6496 N  NE1 . TRP B 1 315 ? 41.905  -3.784  -8.78   1 17.134 ? 307  TRP B NE1 1 
ATOM   6497 C  CE2 . TRP B 1 315 ? 41.974  -3.016  -9.922  1 15.324 ? 307  TRP B CE2 1 
ATOM   6498 C  CE3 . TRP B 1 315 ? 42.218  -0.666  -10.491 1 16.937 ? 307  TRP B CE3 1 
ATOM   6499 C  CZ2 . TRP B 1 315 ? 41.928  -3.407  -11.253 1 16.901 ? 307  TRP B CZ2 1 
ATOM   6500 C  CZ3 . TRP B 1 315 ? 42.212  -1.045  -11.827 1 15.734 ? 307  TRP B CZ3 1 
ATOM   6501 C  CH2 . TRP B 1 315 ? 42.086  -2.399  -12.192 1 17.489 ? 307  TRP B CH2 1 
ATOM   6502 N  N   . HIS B 1 316 ? 44.023  1.987   -5.912  1 19.74  ? 308  HIS B N   1 
ATOM   6503 C  CA  . HIS B 1 316 ? 44.155  3.053   -4.899  1 19.301 ? 308  HIS B CA  1 
ATOM   6504 C  C   . HIS B 1 316 ? 43.408  4.325   -5.315  1 19.746 ? 308  HIS B C   1 
ATOM   6505 O  O   . HIS B 1 316 ? 43.258  4.667   -6.508  1 14.867 ? 308  HIS B O   1 
ATOM   6506 C  CB  . HIS B 1 316 ? 45.62   3.29    -4.473  1 21.765 ? 308  HIS B CB  1 
ATOM   6507 C  CG  . HIS B 1 316 ? 46.439  3.867   -5.565  1 23.088 ? 308  HIS B CG  1 
ATOM   6508 N  ND1 . HIS B 1 316 ? 46.98   5.14    -5.525  1 31.557 ? 308  HIS B ND1 1 
ATOM   6509 C  CD2 . HIS B 1 316 ? 46.787  3.364   -6.762  1 21.158 ? 308  HIS B CD2 1 
ATOM   6510 C  CE1 . HIS B 1 316 ? 47.626  5.379   -6.679  1 22.072 ? 308  HIS B CE1 1 
ATOM   6511 N  NE2 . HIS B 1 316 ? 47.5    4.33    -7.437  1 26.974 ? 308  HIS B NE2 1 
ATOM   6512 N  N   . TRP B 1 317 ? 42.97   5.071   -4.303  1 19.475 ? 309  TRP B N   1 
ATOM   6513 C  CA  . TRP B 1 317 ? 42.421  6.393   -4.581  1 19.588 ? 309  TRP B CA  1 
ATOM   6514 C  C   . TRP B 1 317 ? 43.195  7.422   -3.776  1 17.948 ? 309  TRP B C   1 
ATOM   6515 O  O   . TRP B 1 317 ? 44.359  7.583   -4.076  1 20.819 ? 309  TRP B O   1 
ATOM   6516 C  CB  . TRP B 1 317 ? 40.88   6.491   -4.54   1 19.348 ? 309  TRP B CB  1 
ATOM   6517 C  CG  . TRP B 1 317 ? 40.399  7.905   -4.804  1 20.922 ? 309  TRP B CG  1 
ATOM   6518 C  CD1 . TRP B 1 317 ? 40.497  8.579   -5.986  1 22.359 ? 309  TRP B CD1 1 
ATOM   6519 C  CD2 . TRP B 1 317 ? 39.861  8.835   -3.825  1 23.104 ? 309  TRP B CD2 1 
ATOM   6520 N  NE1 . TRP B 1 317 ? 40.042  9.859   -5.821  1 21.083 ? 309  TRP B NE1 1 
ATOM   6521 C  CE2 . TRP B 1 317 ? 39.644  10.051  -4.51   1 21.553 ? 309  TRP B CE2 1 
ATOM   6522 C  CE3 . TRP B 1 317 ? 39.541  8.749   -2.45   1 22.302 ? 309  TRP B CE3 1 
ATOM   6523 C  CZ2 . TRP B 1 317 ? 39.105  11.171  -3.872  1 21.179 ? 309  TRP B CZ2 1 
ATOM   6524 C  CZ3 . TRP B 1 317 ? 39.011  9.858   -1.809  1 24.598 ? 309  TRP B CZ3 1 
ATOM   6525 C  CH2 . TRP B 1 317 ? 38.807  11.061  -2.519  1 27.905 ? 309  TRP B CH2 1 
ATOM   6526 N  N   . LYS B 1 318 ? 42.606  8.05    -2.736  1 17.043 ? 310  LYS B N   1 
ATOM   6527 C  CA  . LYS B 1 318 ? 43.286  8.99    -1.841  1 16.136 ? 310  LYS B CA  1 
ATOM   6528 C  C   . LYS B 1 318 ? 42.827  8.733   -0.406  1 16.334 ? 310  LYS B C   1 
ATOM   6529 O  O   . LYS B 1 318 ? 41.974  7.901   -0.19   1 16.672 ? 310  LYS B O   1 
ATOM   6530 C  CB  . LYS B 1 318 ? 42.855  10.39   -2.274  1 17.472 ? 310  LYS B CB  1 
ATOM   6531 C  CG  . LYS B 1 318 ? 43.266  10.696  -3.73   1 18.619 ? 310  LYS B CG  1 
ATOM   6532 C  CD  . LYS B 1 318 ? 43.112  12.187  -4.039  1 22.24  ? 310  LYS B CD  1 
ATOM   6533 C  CE  . LYS B 1 318 ? 43.33   12.191  -5.543  1 21.907 ? 310  LYS B CE  1 
ATOM   6534 N  NZ  . LYS B 1 318 ? 43.316  13.56   -6.072  1 26.132 ? 310  LYS B NZ  1 
ATOM   6535 N  N   . ASN B 1 319 ? 43.343  9.458   0.561   1 15.548 ? 311  ASN B N   1 
ATOM   6536 C  CA  . ASN B 1 319 ? 42.996  9.172   1.965   1 17.154 ? 311  ASN B CA  1 
ATOM   6537 C  C   . ASN B 1 319 ? 41.542  9.557   2.273   1 19.642 ? 311  ASN B C   1 
ATOM   6538 O  O   . ASN B 1 319 ? 41.038  10.592  1.815   1 19.143 ? 311  ASN B O   1 
ATOM   6539 C  CB  . ASN B 1 319 ? 43.861  9.995   2.886   1 16.438 ? 311  ASN B CB  1 
ATOM   6540 C  CG  . ASN B 1 319 ? 43.634  9.68    4.354   1 17.275 ? 311  ASN B CG  1 
ATOM   6541 O  OD1 . ASN B 1 319 ? 43.1    10.519  5.081   1 18.452 ? 311  ASN B OD1 1 
ATOM   6542 N  ND2 . ASN B 1 319 ? 43.974  8.474   4.751   1 15.45  ? 311  ASN B ND2 1 
ATOM   6543 N  N   . GLY B 1 320 ? 40.888  8.739   3.123   1 17.736 ? 312  GLY B N   1 
ATOM   6544 C  CA  . GLY B 1 320 ? 39.557  8.937   3.655   1 18.558 ? 312  GLY B CA  1 
ATOM   6545 C  C   . GLY B 1 320 ? 39.035  7.604   4.213   1 19.598 ? 312  GLY B C   1 
ATOM   6546 O  O   . GLY B 1 320 ? 39.749  6.582   4.115   1 14.864 ? 312  GLY B O   1 
ATOM   6547 N  N   . MET B 1 321 ? 37.771  7.585   4.693   1 16.579 ? 313  MET B N   1 
ATOM   6548 C  CA  . MET B 1 321 ? 37.26   6.419   5.427   1 14.205 ? 313  MET B CA  1 
ATOM   6549 C  C   . MET B 1 321 ? 35.92   6.056   4.833   1 15.663 ? 313  MET B C   1 
ATOM   6550 O  O   . MET B 1 321 ? 34.868  6.659   5.169   1 14.156 ? 313  MET B O   1 
ATOM   6551 C  CB  . MET B 1 321 ? 37.344  6.648   6.954   1 12.814 ? 313  MET B CB  1 
ATOM   6552 C  CG  . MET B 1 321 ? 36.783  5.531   7.788   1 13.87  ? 313  MET B CG  1 
ATOM   6553 S  SD  . MET B 1 321 ? 37.23   5.84    9.509   1 17.059 ? 313  MET B SD  1 
ATOM   6554 C  CE  . MET B 1 321 ? 36.32   4.437   10.246  1 13.094 ? 313  MET B CE  1 
ATOM   6555 N  N   . PRO B 1 322 ? 35.898  5.139   3.834   1 15.35  ? 314  PRO B N   1 
ATOM   6556 C  CA  . PRO B 1 322 ? 34.622  4.623   3.371   1 17.153 ? 314  PRO B CA  1 
ATOM   6557 C  C   . PRO B 1 322 ? 34.197  3.497   4.308   1 13.261 ? 314  PRO B C   1 
ATOM   6558 O  O   . PRO B 1 322 ? 34.922  2.489   4.302   1 12.807 ? 314  PRO B O   1 
ATOM   6559 C  CB  . PRO B 1 322 ? 34.918  4.118   1.939   1 16.52  ? 314  PRO B CB  1 
ATOM   6560 C  CG  . PRO B 1 322 ? 36.434  3.692   2.029   1 18.312 ? 314  PRO B CG  1 
ATOM   6561 C  CD  . PRO B 1 322 ? 37.047  4.435   3.227   1 19.872 ? 314  PRO B CD  1 
ATOM   6562 N  N   . ILE B 1 323 ? 33.08   3.679   5.038   1 16.774 ? 315  ILE B N   1 
ATOM   6563 C  CA  . ILE B 1 323 ? 32.856  2.807   6.204   1 15.25  ? 315  ILE B CA  1 
ATOM   6564 C  C   . ILE B 1 323 ? 32.193  1.507   5.774   1 14.166 ? 315  ILE B C   1 
ATOM   6565 O  O   . ILE B 1 323 ? 32.691  0.459   6.153   1 16.701 ? 315  ILE B O   1 
ATOM   6566 C  CB  . ILE B 1 323 ? 32.197  3.473   7.414   1 14.889 ? 315  ILE B CB  1 
ATOM   6567 C  CG1 . ILE B 1 323 ? 32.853  4.786   7.811   1 17.688 ? 315  ILE B CG1 1 
ATOM   6568 C  CG2 . ILE B 1 323 ? 32.049  2.514   8.623   1 10.734 ? 315  ILE B CG2 1 
ATOM   6569 C  CD1 . ILE B 1 323 ? 31.835  5.703   8.492   1 15.566 ? 315  ILE B CD1 1 
ATOM   6570 N  N   . HIS B 1 324 ? 31.087  1.583   5.013   1 17.243 ? 316  HIS B N   1 
ATOM   6571 C  CA  . HIS B 1 324 ? 30.234  0.466   4.635   1 18.655 ? 316  HIS B CA  1 
ATOM   6572 C  C   . HIS B 1 324 ? 29.799  0.639   3.182   1 17.884 ? 316  HIS B C   1 
ATOM   6573 O  O   . HIS B 1 324 ? 29.594  1.752   2.727   1 16.417 ? 316  HIS B O   1 
ATOM   6574 C  CB  . HIS B 1 324 ? 28.982  0.364   5.49    1 15.878 ? 316  HIS B CB  1 
ATOM   6575 C  CG  . HIS B 1 324 ? 29.277  -0.133  6.878   1 15.465 ? 316  HIS B CG  1 
ATOM   6576 N  ND1 . HIS B 1 324 ? 29.006  0.657   7.968   1 14.087 ? 316  HIS B ND1 1 
ATOM   6577 C  CD2 . HIS B 1 324 ? 29.725  -1.286  7.36    1 15.846 ? 316  HIS B CD2 1 
ATOM   6578 C  CE1 . HIS B 1 324 ? 29.258  -0      9.092   1 15.967 ? 316  HIS B CE1 1 
ATOM   6579 N  NE2 . HIS B 1 324 ? 29.742  -1.153  8.725   1 17.513 ? 316  HIS B NE2 1 
ATOM   6580 N  N   . THR B 1 325 ? 29.789  -0.483  2.478   1 14.516 ? 317  THR B N   1 
ATOM   6581 C  CA  . THR B 1 325 ? 29.305  -0.536  1.115   1 14.351 ? 317  THR B CA  1 
ATOM   6582 C  C   . THR B 1 325 ? 27.797  -0.748  1.174   1 16.431 ? 317  THR B C   1 
ATOM   6583 O  O   . THR B 1 325 ? 27.291  -1.344  2.092   1 14.66  ? 317  THR B O   1 
ATOM   6584 C  CB  . THR B 1 325 ? 29.985  -1.622  0.316   1 12.782 ? 317  THR B CB  1 
ATOM   6585 O  OG1 . THR B 1 325 ? 29.764  -2.901  0.943   1 14.655 ? 317  THR B OG1 1 
ATOM   6586 C  CG2 . THR B 1 325 ? 31.473  -1.396  0.168   1 14.187 ? 317  THR B CG2 1 
ATOM   6587 N  N   . ALA B 1 326 ? 27.098  -0.216  0.178   1 15.305 ? 318  ALA B N   1 
ATOM   6588 C  CA  . ALA B 1 326 ? 25.709  -0.547  -0.015  1 15.504 ? 318  ALA B CA  1 
ATOM   6589 C  C   . ALA B 1 326 ? 25.697  -1.923  -0.669  1 18.243 ? 318  ALA B C   1 
ATOM   6590 O  O   . ALA B 1 326 ? 25.392  -2.945  0.004   1 16.355 ? 318  ALA B O   1 
ATOM   6591 C  CB  . ALA B 1 326 ? 25.051  0.514   -0.859  1 15.319 ? 318  ALA B CB  1 
ATOM   6592 N  N   . SER B 1 327 ? 26.056  -1.95   -1.98   1 17.444 ? 319  SER B N   1 
ATOM   6593 C  CA  . SER B 1 327 ? 26.595  -3.19   -2.551  1 15.777 ? 319  SER B CA  1 
ATOM   6594 C  C   . SER B 1 327 ? 27.462  -2.886  -3.779  1 16.278 ? 319  SER B C   1 
ATOM   6595 O  O   . SER B 1 327 ? 27.907  -1.727  -3.95   1 15.522 ? 319  SER B O   1 
ATOM   6596 C  CB  . SER B 1 327 ? 25.436  -4.205  -2.815  1 15.099 ? 319  SER B CB  1 
ATOM   6597 O  OG  . SER B 1 327 ? 25.946  -5.495  -3.139  1 18.802 ? 319  SER B OG  1 
ATOM   6598 N  N   . GLY B 1 328 ? 27.804  -3.953  -4.526  1 18.544 ? 320  GLY B N   1 
ATOM   6599 C  CA  . GLY B 1 328 ? 28.468  -3.765  -5.813  1 17.735 ? 320  GLY B CA  1 
ATOM   6600 C  C   . GLY B 1 328 ? 27.802  -4.516  -6.967  1 16.718 ? 320  GLY B C   1 
ATOM   6601 O  O   . GLY B 1 328 ? 26.872  -5.294  -6.784  1 18.074 ? 320  GLY B O   1 
ATOM   6602 N  N   . PHE B 1 329 ? 28.317  -4.246  -8.172  1 16.348 ? 321  PHE B N   1 
ATOM   6603 C  CA  . PHE B 1 329 ? 27.867  -5.014  -9.33   1 16.921 ? 321  PHE B CA  1 
ATOM   6604 C  C   . PHE B 1 329 ? 28.843  -4.755  -10.463 1 18.174 ? 321  PHE B C   1 
ATOM   6605 O  O   . PHE B 1 329 ? 29.69   -3.88   -10.325 1 18.874 ? 321  PHE B O   1 
ATOM   6606 C  CB  . PHE B 1 329 ? 26.412  -4.731  -9.736  1 15.585 ? 321  PHE B CB  1 
ATOM   6607 C  CG  . PHE B 1 329 ? 26.126  -3.343  -10.304 1 18.139 ? 321  PHE B CG  1 
ATOM   6608 C  CD1 . PHE B 1 329 ? 25.861  -2.274  -9.447  1 18.821 ? 321  PHE B CD1 1 
ATOM   6609 C  CD2 . PHE B 1 329 ? 26.128  -3.129  -11.708 1 18.391 ? 321  PHE B CD2 1 
ATOM   6610 C  CE1 . PHE B 1 329 ? 25.641  -0.992  -9.925  1 17.355 ? 321  PHE B CE1 1 
ATOM   6611 C  CE2 . PHE B 1 329 ? 25.869  -1.865  -12.218 1 19.151 ? 321  PHE B CE2 1 
ATOM   6612 C  CZ  . PHE B 1 329 ? 25.631  -0.803  -11.334 1 24.576 ? 321  PHE B CZ  1 
ATOM   6613 N  N   . GLU B 1 330 ? 28.607  -5.413  -11.626 1 18.828 ? 322  GLU B N   1 
ATOM   6614 C  CA  . GLU B 1 330 ? 29.434  -5.107  -12.793 1 20.141 ? 322  GLU B CA  1 
ATOM   6615 C  C   . GLU B 1 330 ? 28.508  -4.564  -13.868 1 18.359 ? 322  GLU B C   1 
ATOM   6616 O  O   . GLU B 1 330 ? 27.457  -5.151  -14.136 1 19.486 ? 322  GLU B O   1 
ATOM   6617 C  CB  . GLU B 1 330 ? 30.242  -6.321  -13.283 1 21.587 ? 322  GLU B CB  1 
ATOM   6618 C  CG  . GLU B 1 330 ? 31.435  -6.66   -12.378 1 20.626 ? 322  GLU B CG  1 
ATOM   6619 C  CD  . GLU B 1 330 ? 31.773  -8.122  -12.536 1 21.426 ? 322  GLU B CD  1 
ATOM   6620 O  OE1 . GLU B 1 330 ? 31.909  -8.564  -13.709 1 18.436 ? 322  GLU B OE1 1 
ATOM   6621 O  OE2 . GLU B 1 330 ? 31.855  -8.827  -11.523 1 17.665 ? 322  GLU B OE2 1 
ATOM   6622 N  N   . ASP B 1 331 ? 28.867  -3.407  -14.405 1 18.542 ? 323  ASP B N   1 
ATOM   6623 C  CA  . ASP B 1 331 ? 28.034  -2.754  -15.406 1 24.869 ? 323  ASP B CA  1 
ATOM   6624 C  C   . ASP B 1 331 ? 28.144  -3.506  -16.74  1 25.051 ? 323  ASP B C   1 
ATOM   6625 O  O   . ASP B 1 331 ? 28.86   -4.502  -16.814 1 18.601 ? 323  ASP B O   1 
ATOM   6626 C  CB  . ASP B 1 331 ? 28.336  -1.262  -15.509 1 25.9   ? 323  ASP B CB  1 
ATOM   6627 C  CG  . ASP B 1 331 ? 29.66   -0.878  -16.16  1 20.892 ? 323  ASP B CG  1 
ATOM   6628 O  OD1 . ASP B 1 331 ? 30.362  -1.77   -16.699 1 23.451 ? 323  ASP B OD1 1 
ATOM   6629 O  OD2 . ASP B 1 331 ? 30.017  0.301   -16.072 1 21.491 ? 323  ASP B OD2 1 
ATOM   6630 N  N   . GLU B 1 332 ? 27.445  -2.983  -17.782 1 24.299 ? 324  GLU B N   1 
ATOM   6631 C  CA  . GLU B 1 332 ? 27.425  -3.52   -19.154 1 32.824 ? 324  GLU B CA  1 
ATOM   6632 C  C   . GLU B 1 332 ? 28.807  -3.884  -19.716 1 28.595 ? 324  GLU B C   1 
ATOM   6633 O  O   . GLU B 1 332 ? 28.937  -4.884  -20.457 1 30.866 ? 324  GLU B O   1 
ATOM   6634 C  CB  . GLU B 1 332 ? 26.72   -2.571  -20.137 1 31.517 ? 324  GLU B CB  1 
ATOM   6635 C  CG  . GLU B 1 332 ? 27.122  -1.088  -20.114 1 41.911 ? 324  GLU B CG  1 
ATOM   6636 C  CD  . GLU B 1 332 ? 26.807  -0.166  -18.918 1 54.007 ? 324  GLU B CD  1 
ATOM   6637 O  OE1 . GLU B 1 332 ? 25.91   -0.469  -18.066 1 48.224 ? 324  GLU B OE1 1 
ATOM   6638 O  OE2 . GLU B 1 332 ? 27.533  0.86    -18.791 1 55.712 ? 324  GLU B OE2 1 
ATOM   6639 N  N   . GLN B 1 333 ? 29.799  -3.019  -19.414 1 27.922 ? 325  GLN B N   1 
ATOM   6640 C  CA  . GLN B 1 333 ? 31.164  -3.08   -19.924 1 25.745 ? 325  GLN B CA  1 
ATOM   6641 C  C   . GLN B 1 333 ? 32.12   -3.595  -18.843 1 23.419 ? 325  GLN B C   1 
ATOM   6642 O  O   . GLN B 1 333 ? 33.305  -3.336  -18.944 1 24.405 ? 325  GLN B O   1 
ATOM   6643 C  CB  . GLN B 1 333 ? 31.828  -1.816  -20.474 1 28.096 ? 325  GLN B CB  1 
ATOM   6644 C  CG  . GLN B 1 333 ? 30.933  -0.762  -21.105 1 34.717 ? 325  GLN B CG  1 
ATOM   6645 C  CD  . GLN B 1 333 ? 31.458  0.655   -20.949 1 39.573 ? 325  GLN B CD  1 
ATOM   6646 O  OE1 . GLN B 1 333 ? 32.611  0.923   -20.586 1 35.763 ? 325  GLN B OE1 1 
ATOM   6647 N  NE2 . GLN B 1 333 ? 30.58   1.598   -21.223 1 40.838 ? 325  GLN B NE2 1 
ATOM   6648 N  N   . GLY B 1 334 ? 31.586  -4.341  -17.847 1 25.117 ? 326  GLY B N   1 
ATOM   6649 C  CA  . GLY B 1 334 ? 32.33   -5.159  -16.888 1 21.268 ? 326  GLY B CA  1 
ATOM   6650 C  C   . GLY B 1 334 ? 32.98   -4.353  -15.769 1 20.568 ? 326  GLY B C   1 
ATOM   6651 O  O   . GLY B 1 334 ? 33.809  -4.901  -15.018 1 18.401 ? 326  GLY B O   1 
ATOM   6652 N  N   . ARG B 1 335 ? 32.649  -3.058  -15.686 1 18.155 ? 327  ARG B N   1 
ATOM   6653 C  CA  . ARG B 1 335 ? 33.273  -2.242  -14.639 1 17.403 ? 327  ARG B CA  1 
ATOM   6654 C  C   . ARG B 1 335 ? 32.598  -2.549  -13.296 1 15.548 ? 327  ARG B C   1 
ATOM   6655 O  O   . ARG B 1 335 ? 31.384  -2.648  -13.243 1 18.273 ? 327  ARG B O   1 
ATOM   6656 C  CB  . ARG B 1 335 ? 33.28   -0.735  -14.924 1 17.962 ? 327  ARG B CB  1 
ATOM   6657 C  CG  . ARG B 1 335 ? 33.659  -0.512  -16.395 1 19.895 ? 327  ARG B CG  1 
ATOM   6658 C  CD  . ARG B 1 335 ? 33.828  0.949   -16.758 1 24.589 ? 327  ARG B CD  1 
ATOM   6659 N  NE  . ARG B 1 335 ? 32.522  1.62    -16.669 1 32.36  ? 327  ARG B NE  1 
ATOM   6660 C  CZ  . ARG B 1 335 ? 32.229  2.864   -17.057 1 40.948 ? 327  ARG B CZ  1 
ATOM   6661 N  NH1 . ARG B 1 335 ? 33.184  3.772   -17.199 1 39.069 ? 327  ARG B NH1 1 
ATOM   6662 N  NH2 . ARG B 1 335 ? 30.957  3.181   -17.279 1 39.249 ? 327  ARG B NH2 1 
ATOM   6663 N  N   . ILE B 1 336 ? 33.41   -2.678  -12.251 1 16.367 ? 328  ILE B N   1 
ATOM   6664 C  CA  . ILE B 1 336 ? 33.006  -2.839  -10.864 1 15.396 ? 328  ILE B CA  1 
ATOM   6665 C  C   . ILE B 1 336 ? 32.525  -1.493  -10.34  1 14.765 ? 328  ILE B C   1 
ATOM   6666 O  O   . ILE B 1 336 ? 33.278  -0.51   -10.338 1 15.188 ? 328  ILE B O   1 
ATOM   6667 C  CB  . ILE B 1 336 ? 34.185  -3.363  -10.022 1 17.23  ? 328  ILE B CB  1 
ATOM   6668 C  CG1 . ILE B 1 336 ? 34.702  -4.755  -10.481 1 19.435 ? 328  ILE B CG1 1 
ATOM   6669 C  CG2 . ILE B 1 336 ? 33.884  -3.293  -8.501  1 15.823 ? 328  ILE B CG2 1 
ATOM   6670 C  CD1 . ILE B 1 336 ? 36.026  -5.186  -9.887  1 20.179 ? 328  ILE B CD1 1 
ATOM   6671 N  N   . ILE B 1 337 ? 31.251  -1.451  -9.938  1 15.442 ? 329  ILE B N   1 
ATOM   6672 C  CA  . ILE B 1 337 ? 30.617  -0.242  -9.447  1 14.441 ? 329  ILE B CA  1 
ATOM   6673 C  C   . ILE B 1 337 ? 30.199  -0.562  -8.017  1 15.013 ? 329  ILE B C   1 
ATOM   6674 O  O   . ILE B 1 337 ? 29.437  -1.515  -7.812  1 15.645 ? 329  ILE B O   1 
ATOM   6675 C  CB  . ILE B 1 337 ? 29.39   0.104   -10.294 1 18.273 ? 329  ILE B CB  1 
ATOM   6676 C  CG1 . ILE B 1 337 ? 29.7    0.18    -11.851 1 17.773 ? 329  ILE B CG1 1 
ATOM   6677 C  CG2 . ILE B 1 337 ? 28.664  1.352   -9.743  1 15.539 ? 329  ILE B CG2 1 
ATOM   6678 C  CD1 . ILE B 1 337 ? 30.816  1.136   -12.235 1 17.519 ? 329  ILE B CD1 1 
ATOM   6679 N  N   . ILE B 1 338 ? 30.715  0.207   -7.067  1 15.382 ? 330  ILE B N   1 
ATOM   6680 C  CA  . ILE B 1 338 ? 30.402  -0.019  -5.648  1 13.756 ? 330  ILE B CA  1 
ATOM   6681 C  C   . ILE B 1 338 ? 29.942  1.331   -5.059  1 13.233 ? 330  ILE B C   1 
ATOM   6682 O  O   . ILE B 1 338 ? 30.666  2.342   -5.226  1 15.572 ? 330  ILE B O   1 
ATOM   6683 C  CB  . ILE B 1 338 ? 31.666  -0.509  -4.967  1 14.142 ? 330  ILE B CB  1 
ATOM   6684 C  CG1 . ILE B 1 338 ? 32.187  -1.81   -5.577  1 15.442 ? 330  ILE B CG1 1 
ATOM   6685 C  CG2 . ILE B 1 338 ? 31.433  -0.598  -3.417  1 13.921 ? 330  ILE B CG2 1 
ATOM   6686 C  CD1 . ILE B 1 338 ? 33.628  -2.169  -5.21   1 16.423 ? 330  ILE B CD1 1 
ATOM   6687 N  N   . ASP B 1 339 ? 28.872  1.343   -4.245  1 12.378 ? 331  ASP B N   1 
ATOM   6688 C  CA  . ASP B 1 339 ? 28.522  2.555   -3.534  1 15.812 ? 331  ASP B CA  1 
ATOM   6689 C  C   . ASP B 1 339 ? 28.851  2.328   -2.057  1 17.272 ? 331  ASP B C   1 
ATOM   6690 O  O   . ASP B 1 339 ? 28.755  1.203   -1.57   1 16.283 ? 331  ASP B O   1 
ATOM   6691 C  CB  . ASP B 1 339 ? 27.05   2.934   -3.675  1 16.508 ? 331  ASP B CB  1 
ATOM   6692 C  CG  . ASP B 1 339 ? 26.564  3.401   -5.056  1 19.519 ? 331  ASP B CG  1 
ATOM   6693 O  OD1 . ASP B 1 339 ? 27.35   3.272   -6.028  1 20.891 ? 331  ASP B OD1 1 
ATOM   6694 O  OD2 . ASP B 1 339 ? 25.373  3.844   -5.168  1 21.311 ? 331  ASP B OD2 1 
ATOM   6695 N  N   . SER B 1 340 ? 29.237  3.408   -1.388  1 18.359 ? 332  SER B N   1 
ATOM   6696 C  CA  . SER B 1 340 ? 29.697  3.351   0.003   1 16.43  ? 332  SER B CA  1 
ATOM   6697 C  C   . SER B 1 340 ? 29.502  4.686   0.66    1 15.273 ? 332  SER B C   1 
ATOM   6698 O  O   . SER B 1 340 ? 29.428  5.692   -0.026  1 17.095 ? 332  SER B O   1 
ATOM   6699 C  CB  . SER B 1 340 ? 31.151  2.974   0.098   1 15.859 ? 332  SER B CB  1 
ATOM   6700 O  OG  . SER B 1 340 ? 32.072  4.013   -0.194  1 18.15  ? 332  SER B OG  1 
ATOM   6701 N  N   . SER B 1 341 ? 29.518  4.694   2.009   1 13.217 ? 333  SER B N   1 
ATOM   6702 C  CA  . SER B 1 341 ? 29.723  5.983   2.623   1 14.876 ? 333  SER B CA  1 
ATOM   6703 C  C   . SER B 1 341 ? 31.194  6.376   2.437   1 15.756 ? 333  SER B C   1 
ATOM   6704 O  O   . SER B 1 341 ? 32.041  5.559   2.056   1 16.836 ? 333  SER B O   1 
ATOM   6705 C  CB  . SER B 1 341 ? 29.323  5.936   4.091   1 15.75  ? 333  SER B CB  1 
ATOM   6706 O  OG  . SER B 1 341 ? 30.036  4.877   4.673   1 15.664 ? 333  SER B OG  1 
ATOM   6707 N  N   . LEU B 1 342 ? 31.464  7.678   2.552   1 16.306 ? 334  LEU B N   1 
ATOM   6708 C  CA  . LEU B 1 342 ? 32.806  8.244   2.551   1 16.502 ? 334  LEU B CA  1 
ATOM   6709 C  C   . LEU B 1 342 ? 32.826  9.417   3.526   1 16.726 ? 334  LEU B C   1 
ATOM   6710 O  O   . LEU B 1 342 ? 32.087  10.388  3.36    1 22.577 ? 334  LEU B O   1 
ATOM   6711 C  CB  . LEU B 1 342 ? 33.196  8.747   1.151   1 12.955 ? 334  LEU B CB  1 
ATOM   6712 C  CG  . LEU B 1 342 ? 34.586  9.365   1.018   1 16.533 ? 334  LEU B CG  1 
ATOM   6713 C  CD1 . LEU B 1 342 ? 35.813  8.517   1.463   1 14.862 ? 334  LEU B CD1 1 
ATOM   6714 C  CD2 . LEU B 1 342 ? 34.689  9.739   -0.525  1 16.38  ? 334  LEU B CD2 1 
ATOM   6715 N  N   . VAL B 1 343 ? 33.681  9.283   4.513   1 16.253 ? 335  VAL B N   1 
ATOM   6716 C  CA  . VAL B 1 343 ? 33.947  10.261  5.553   1 17.287 ? 335  VAL B CA  1 
ATOM   6717 C  C   . VAL B 1 343 ? 35.379  10.725  5.333   1 18.045 ? 335  VAL B C   1 
ATOM   6718 O  O   . VAL B 1 343 ? 36.298  9.907   5.193   1 17.178 ? 335  VAL B O   1 
ATOM   6719 C  CB  . VAL B 1 343 ? 33.809  9.647   6.966   1 16.621 ? 335  VAL B CB  1 
ATOM   6720 C  CG1 . VAL B 1 343 ? 34.081  10.689  8.038   1 17.406 ? 335  VAL B CG1 1 
ATOM   6721 C  CG2 . VAL B 1 343 ? 32.419  9.04    7.165   1 18.95  ? 335  VAL B CG2 1 
ATOM   6722 N  N   . HIS B 1 344 ? 35.55   12.046  5.239   1 17.021 ? 336  HIS B N   1 
ATOM   6723 C  CA  . HIS B 1 344 ? 36.766  12.632  4.72    1 18.063 ? 336  HIS B CA  1 
ATOM   6724 C  C   . HIS B 1 344 ? 37.67   12.968  5.917   1 21.085 ? 336  HIS B C   1 
ATOM   6725 O  O   . HIS B 1 344 ? 37.893  14.135  6.216   1 17.819 ? 336  HIS B O   1 
ATOM   6726 C  CB  . HIS B 1 344 ? 36.438  13.853  3.847   1 18.688 ? 336  HIS B CB  1 
ATOM   6727 C  CG  . HIS B 1 344 ? 35.666  13.565  2.588   1 17.818 ? 336  HIS B CG  1 
ATOM   6728 N  ND1 . HIS B 1 344 ? 36.257  13.148  1.415   1 21.332 ? 336  HIS B ND1 1 
ATOM   6729 C  CD2 . HIS B 1 344 ? 34.352  13.706  2.306   1 21.243 ? 336  HIS B CD2 1 
ATOM   6730 C  CE1 . HIS B 1 344 ? 35.35   13.059  0.47    1 19.728 ? 336  HIS B CE1 1 
ATOM   6731 N  NE2 . HIS B 1 344 ? 34.182  13.317  0.989   1 23.16  ? 336  HIS B NE2 1 
ATOM   6732 N  N   . GLY B 1 345 ? 38.217  11.914  6.55    1 16.541 ? 337  GLY B N   1 
ATOM   6733 C  CA  . GLY B 1 345 ? 38.772  12.013  7.888   1 17.494 ? 337  GLY B CA  1 
ATOM   6734 C  C   . GLY B 1 345 ? 38.447  10.784  8.722   1 18.49  ? 337  GLY B C   1 
ATOM   6735 O  O   . GLY B 1 345 ? 37.885  9.813   8.263   1 14.107 ? 337  GLY B O   1 
ATOM   6736 N  N   . ASN B 1 346 ? 38.75   10.886  10.011  1 16.274 ? 338  ASN B N   1 
ATOM   6737 C  CA  . ASN B 1 346 ? 38.681  9.688   10.835  1 18.229 ? 338  ASN B CA  1 
ATOM   6738 C  C   . ASN B 1 346 ? 37.344  9.624   11.561  1 20.104 ? 338  ASN B C   1 
ATOM   6739 O  O   . ASN B 1 346 ? 37.087  10.418  12.495  1 22.165 ? 338  ASN B O   1 
ATOM   6740 C  CB  . ASN B 1 346 ? 39.943  9.56    11.687  1 17.835 ? 338  ASN B CB  1 
ATOM   6741 C  CG  . ASN B 1 346 ? 39.925  8.385   12.624  1 16.781 ? 338  ASN B CG  1 
ATOM   6742 O  OD1 . ASN B 1 346 ? 39.109  7.468   12.48   1 12.252 ? 338  ASN B OD1 1 
ATOM   6743 N  ND2 . ASN B 1 346 ? 40.842  8.368   13.587  1 15.921 ? 338  ASN B ND2 1 
ATOM   6744 N  N   . ALA B 1 347 ? 36.515  8.628   11.182  1 16.251 ? 339  ALA B N   1 
ATOM   6745 C  CA  . ALA B 1 347 ? 35.233  8.439   11.863  1 13.176 ? 339  ALA B CA  1 
ATOM   6746 C  C   . ALA B 1 347 ? 35.353  7.688   13.205  1 13.719 ? 339  ALA B C   1 
ATOM   6747 O  O   . ALA B 1 347 ? 34.326  7.556   13.887  1 12.413 ? 339  ALA B O   1 
ATOM   6748 C  CB  . ALA B 1 347 ? 34.213  7.769   10.971  1 11.737 ? 339  ALA B CB  1 
ATOM   6749 N  N   . PHE B 1 348 ? 36.539  7.048   13.461  1 13.776 ? 340  PHE B N   1 
ATOM   6750 C  CA  . PHE B 1 348 ? 36.865  6.434   14.758  1 14.08  ? 340  PHE B CA  1 
ATOM   6751 C  C   . PHE B 1 348 ? 37.996  7.245   15.395  1 16.028 ? 340  PHE B C   1 
ATOM   6752 O  O   . PHE B 1 348 ? 39.137  6.771   15.503  1 13.788 ? 340  PHE B O   1 
ATOM   6753 C  CB  . PHE B 1 348 ? 37.312  4.969   14.5    1 13.938 ? 340  PHE B CB  1 
ATOM   6754 C  CG  . PHE B 1 348 ? 36.274  3.901   14.193  1 16.714 ? 340  PHE B CG  1 
ATOM   6755 C  CD1 . PHE B 1 348 ? 34.885  4.165   14.195  1 19.713 ? 340  PHE B CD1 1 
ATOM   6756 C  CD2 . PHE B 1 348 ? 36.681  2.578   13.961  1 17.132 ? 340  PHE B CD2 1 
ATOM   6757 C  CE1 . PHE B 1 348 ? 33.96   3.136   13.971  1 19.906 ? 340  PHE B CE1 1 
ATOM   6758 C  CE2 . PHE B 1 348 ? 35.732  1.573   13.706  1 18.503 ? 340  PHE B CE2 1 
ATOM   6759 C  CZ  . PHE B 1 348 ? 34.401  1.843   13.714  1 16.747 ? 340  PHE B CZ  1 
ATOM   6760 N  N   . PRO B 1 349 ? 37.728  8.467   15.906  1 18.063 ? 341  PRO B N   1 
ATOM   6761 C  CA  . PRO B 1 349 ? 38.788  9.29    16.472  1 17.641 ? 341  PRO B CA  1 
ATOM   6762 C  C   . PRO B 1 349 ? 39.422  8.716   17.734  1 20.373 ? 341  PRO B C   1 
ATOM   6763 O  O   . PRO B 1 349 ? 40.493  9.187   18.129  1 17.676 ? 341  PRO B O   1 
ATOM   6764 C  CB  . PRO B 1 349 ? 38.072  10.606  16.767  1 16.773 ? 341  PRO B CB  1 
ATOM   6765 C  CG  . PRO B 1 349 ? 36.639  10.201  16.972  1 18.943 ? 341  PRO B CG  1 
ATOM   6766 C  CD  . PRO B 1 349 ? 36.413  9.142   15.943  1 16.808 ? 341  PRO B CD  1 
ATOM   6767 N  N   . PHE B 1 350 ? 38.768  7.697   18.321  1 17.093 ? 342  PHE B N   1 
ATOM   6768 C  CA  . PHE B 1 350 ? 39.253  7.013   19.516  1 14.695 ? 342  PHE B CA  1 
ATOM   6769 C  C   . PHE B 1 350 ? 40.449  6.108   19.158  1 14.8   ? 342  PHE B C   1 
ATOM   6770 O  O   . PHE B 1 350 ? 41.131  5.625   20.055  1 14.583 ? 342  PHE B O   1 
ATOM   6771 C  CB  . PHE B 1 350 ? 38.163  6.203   20.212  1 17.367 ? 342  PHE B CB  1 
ATOM   6772 C  CG  . PHE B 1 350 ? 37.252  5.417   19.28   1 16.449 ? 342  PHE B CG  1 
ATOM   6773 C  CD1 . PHE B 1 350 ? 37.586  4.105   18.912  1 18.168 ? 342  PHE B CD1 1 
ATOM   6774 C  CD2 . PHE B 1 350 ? 36.061  5.968   18.821  1 17.124 ? 342  PHE B CD2 1 
ATOM   6775 C  CE1 . PHE B 1 350 ? 36.757  3.412   18.026  1 14.764 ? 342  PHE B CE1 1 
ATOM   6776 C  CE2 . PHE B 1 350 ? 35.224  5.284   17.941  1 15.933 ? 342  PHE B CE2 1 
ATOM   6777 C  CZ  . PHE B 1 350 ? 35.564  3.978   17.567  1 16.156 ? 342  PHE B CZ  1 
ATOM   6778 N  N   . PHE B 1 351 ? 40.704  5.873   17.848  1 12.842 ? 343  PHE B N   1 
ATOM   6779 C  CA  . PHE B 1 351 ? 41.955  5.31    17.327  1 13.414 ? 343  PHE B CA  1 
ATOM   6780 C  C   . PHE B 1 351 ? 42.72   6.395   16.563  1 15.748 ? 343  PHE B C   1 
ATOM   6781 O  O   . PHE B 1 351 ? 42.8    6.393   15.303  1 14.128 ? 343  PHE B O   1 
ATOM   6782 C  CB  . PHE B 1 351 ? 41.74   4.052   16.466  1 16.939 ? 343  PHE B CB  1 
ATOM   6783 C  CG  . PHE B 1 351 ? 40.947  2.912   17.129  1 17.823 ? 343  PHE B CG  1 
ATOM   6784 C  CD1 . PHE B 1 351 ? 41.026  2.679   18.53   1 15.692 ? 343  PHE B CD1 1 
ATOM   6785 C  CD2 . PHE B 1 351 ? 40.16   2.065   16.341  1 15.413 ? 343  PHE B CD2 1 
ATOM   6786 C  CE1 . PHE B 1 351 ? 40.314  1.61    19.128  1 15.43  ? 343  PHE B CE1 1 
ATOM   6787 C  CE2 . PHE B 1 351 ? 39.44   1.021   16.922  1 16.505 ? 343  PHE B CE2 1 
ATOM   6788 C  CZ  . PHE B 1 351 ? 39.518  0.799   18.333  1 17.65  ? 343  PHE B CZ  1 
ATOM   6789 N  N   . PRO B 1 352 ? 43.378  7.338   17.274  1 15.107 ? 344  PRO B N   1 
ATOM   6790 C  CA  . PRO B 1 352 ? 44.056  8.414   16.56   1 19.077 ? 344  PRO B CA  1 
ATOM   6791 C  C   . PRO B 1 352 ? 45.338  7.981   15.819  1 19.212 ? 344  PRO B C   1 
ATOM   6792 O  O   . PRO B 1 352 ? 45.854  6.863   16.031  1 18.48  ? 344  PRO B O   1 
ATOM   6793 C  CB  . PRO B 1 352 ? 44.395  9.438   17.657  1 19.039 ? 344  PRO B CB  1 
ATOM   6794 C  CG  . PRO B 1 352 ? 44.538  8.543   18.905  1 20.072 ? 344  PRO B CG  1 
ATOM   6795 C  CD  . PRO B 1 352 ? 43.518  7.432   18.755  1 18.975 ? 344  PRO B CD  1 
ATOM   6796 N  N   . PRO B 1 353 ? 45.932  8.863   14.95   1 21.922 ? 345  PRO B N   1 
ATOM   6797 C  CA  . PRO B 1 353 ? 47.264  8.62    14.4    1 18.924 ? 345  PRO B CA  1 
ATOM   6798 C  C   . PRO B 1 353 ? 48.296  8.45    15.504  1 21.185 ? 345  PRO B C   1 
ATOM   6799 O  O   . PRO B 1 353 ? 48.041  8.843   16.659  1 21.381 ? 345  PRO B O   1 
ATOM   6800 C  CB  . PRO B 1 353 ? 47.544  9.855   13.546  1 17.801 ? 345  PRO B CB  1 
ATOM   6801 C  CG  . PRO B 1 353 ? 46.151  10.408  13.211  1 16.306 ? 345  PRO B CG  1 
ATOM   6802 C  CD  . PRO B 1 353 ? 45.363  10.141  14.459  1 19.445 ? 345  PRO B CD  1 
ATOM   6803 N  N   . ASP B 1 354 ? 49.434  7.823   15.143  1 24.138 ? 346  ASP B N   1 
ATOM   6804 C  CA  . ASP B 1 354 ? 50.602  7.73    16.01   1 29.858 ? 346  ASP B CA  1 
ATOM   6805 C  C   . ASP B 1 354 ? 51.314  9.064   16.201  1 28.392 ? 346  ASP B C   1 
ATOM   6806 O  O   . ASP B 1 354 ? 51.689  9.401   17.334  1 31.308 ? 346  ASP B O   1 
ATOM   6807 C  CB  . ASP B 1 354 ? 51.724  6.91    15.389  1 37.752 ? 346  ASP B CB  1 
ATOM   6808 C  CG  . ASP B 1 354 ? 51.748  5.429   15.691  1 40.286 ? 346  ASP B CG  1 
ATOM   6809 O  OD1 . ASP B 1 354 ? 51.713  5.086   16.888  1 37.329 ? 346  ASP B OD1 1 
ATOM   6810 O  OD2 . ASP B 1 354 ? 51.924  4.666   14.72   1 48.505 ? 346  ASP B OD2 1 
ATOM   6811 N  N   . SER B 1 355 ? 51.567  9.785   15.101  1 25.566 ? 347  SER B N   1 
ATOM   6812 C  CA  . SER B 1 355 ? 52.573  10.848  15.176  1 28.015 ? 347  SER B CA  1 
ATOM   6813 C  C   . SER B 1 355 ? 51.9    12.11   15.711  1 30.468 ? 347  SER B C   1 
ATOM   6814 O  O   . SER B 1 355 ? 50.697  12.291  15.522  1 19.969 ? 347  SER B O   1 
ATOM   6815 C  CB  . SER B 1 355 ? 53.246  11.098  13.847  1 33.006 ? 347  SER B CB  1 
ATOM   6816 O  OG  . SER B 1 355 ? 52.4    11.812  12.935  1 26.962 ? 347  SER B OG  1 
ATOM   6817 N  N   . ASP B 1 356 ? 52.677  12.962  16.393  1 30.433 ? 348  ASP B N   1 
ATOM   6818 C  CA  . ASP B 1 356 ? 52.177  14.215  16.94   1 29.909 ? 348  ASP B CA  1 
ATOM   6819 C  C   . ASP B 1 356 ? 51.578  15.03   15.815  1 25.644 ? 348  ASP B C   1 
ATOM   6820 O  O   . ASP B 1 356 ? 50.501  15.571  15.984  1 23.517 ? 348  ASP B O   1 
ATOM   6821 C  CB  . ASP B 1 356 ? 53.293  15.008  17.612  1 37.08  ? 348  ASP B CB  1 
ATOM   6822 C  CG  . ASP B 1 356 ? 53.488  14.717  19.093  1 49.635 ? 348  ASP B CG  1 
ATOM   6823 O  OD1 . ASP B 1 356 ? 52.583  14.11   19.719  1 50.16  ? 348  ASP B OD1 1 
ATOM   6824 O  OD2 . ASP B 1 356 ? 54.546  15.127  19.616  1 51.538 ? 348  ASP B OD2 1 
ATOM   6825 N  N   . GLU B 1 357 ? 52.276  15.046  14.672  1 24.841 ? 349  GLU B N   1 
ATOM   6826 C  CA  . GLU B 1 357 ? 51.865  15.788  13.49   1 25.913 ? 349  GLU B CA  1 
ATOM   6827 C  C   . GLU B 1 357 ? 50.441  15.395  13.044  1 27.149 ? 349  GLU B C   1 
ATOM   6828 O  O   . GLU B 1 357 ? 49.579  16.272  12.85   1 22.285 ? 349  GLU B O   1 
ATOM   6829 C  CB  . GLU B 1 357 ? 52.989  15.687  12.461  1 30.419 ? 349  GLU B CB  1 
ATOM   6830 C  CG  . GLU B 1 357 ? 52.613  16.33   11.125  1 45.975 ? 349  GLU B CG  1 
ATOM   6831 C  CD  . GLU B 1 357 ? 53.597  16.414  9.955   1 60.541 ? 349  GLU B CD  1 
ATOM   6832 O  OE1 . GLU B 1 357 ? 54.758  16.831  10.167  1 66.901 ? 349  GLU B OE1 1 
ATOM   6833 O  OE2 . GLU B 1 357 ? 53.191  16.12   8.798   1 71.607 ? 349  GLU B OE2 1 
ATOM   6834 N  N   . GLN B 1 358 ? 50.187  14.088  12.873  1 21.287 ? 350  GLN B N   1 
ATOM   6835 C  CA  . GLN B 1 358 ? 48.876  13.635  12.386  1 25.773 ? 350  GLN B CA  1 
ATOM   6836 C  C   . GLN B 1 358 ? 47.805  13.776  13.465  1 20.267 ? 350  GLN B C   1 
ATOM   6837 O  O   . GLN B 1 358 ? 46.649  14.059  13.138  1 20.447 ? 350  GLN B O   1 
ATOM   6838 C  CB  . GLN B 1 358 ? 48.897  12.227  11.801  1 23.678 ? 350  GLN B CB  1 
ATOM   6839 C  CG  . GLN B 1 358 ? 49.758  12.073  10.544  1 23.26  ? 350  GLN B CG  1 
ATOM   6840 C  CD  . GLN B 1 358 ? 49.432  10.797  9.785   1 26.238 ? 350  GLN B CD  1 
ATOM   6841 O  OE1 . GLN B 1 358 ? 48.315  10.268  9.915   1 21.424 ? 350  GLN B OE1 1 
ATOM   6842 N  NE2 . GLN B 1 358 ? 50.373  10.305  8.97    1 21.935 ? 350  GLN B NE2 1 
ATOM   6843 N  N   . LYS B 1 359 ? 48.206  13.621  14.732  1 21.311 ? 351  LYS B N   1 
ATOM   6844 C  CA  . LYS B 1 359 ? 47.319  13.827  15.869  1 22.287 ? 351  LYS B CA  1 
ATOM   6845 C  C   . LYS B 1 359 ? 46.786  15.248  15.859  1 27.479 ? 351  LYS B C   1 
ATOM   6846 O  O   . LYS B 1 359 ? 45.6    15.47   16.082  1 22.587 ? 351  LYS B O   1 
ATOM   6847 C  CB  . LYS B 1 359 ? 47.949  13.653  17.248  1 21.34  ? 351  LYS B CB  1 
ATOM   6848 C  CG  . LYS B 1 359 ? 47.943  12.204  17.621  1 24.238 ? 351  LYS B CG  1 
ATOM   6849 C  CD  . LYS B 1 359 ? 48.368  12.182  19.095  1 29.407 ? 351  LYS B CD  1 
ATOM   6850 C  CE  . LYS B 1 359 ? 49.143  10.943  19.483  1 39.435 ? 351  LYS B CE  1 
ATOM   6851 N  NZ  . LYS B 1 359 ? 50.131  11.179  20.547  1 36.361 ? 351  LYS B NZ  1 
ATOM   6852 N  N   . LYS B 1 360 ? 47.685  16.196  15.6    1 25.846 ? 352  LYS B N   1 
ATOM   6853 C  CA  . LYS B 1 360 ? 47.282  17.583  15.594  1 28.05  ? 352  LYS B CA  1 
ATOM   6854 C  C   . LYS B 1 360 ? 46.279  17.82   14.449  1 27.679 ? 352  LYS B C   1 
ATOM   6855 O  O   . LYS B 1 360 ? 45.301  18.543  14.641  1 32.681 ? 352  LYS B O   1 
ATOM   6856 C  CB  . LYS B 1 360 ? 48.555  18.433  15.604  1 23.013 ? 352  LYS B CB  1 
ATOM   6857 C  CG  . LYS B 1 360 ? 49.151  18.475  17.026  1 36.43  ? 352  LYS B CG  1 
ATOM   6858 C  CD  . LYS B 1 360 ? 50.532  19.067  17.306  1 37.622 ? 352  LYS B CD  1 
ATOM   6859 C  CE  . LYS B 1 360 ? 51.19   18.314  18.424  1 41.074 ? 352  LYS B CE  1 
ATOM   6860 N  NZ  . LYS B 1 360 ? 50.534  18.483  19.734  1 39.233 ? 352  LYS B NZ  1 
ATOM   6861 N  N   . LYS B 1 361 ? 46.498  17.158  13.313  1 23.214 ? 353  LYS B N   1 
ATOM   6862 C  CA  . LYS B 1 361 ? 45.639  17.334  12.152  1 21.865 ? 353  LYS B CA  1 
ATOM   6863 C  C   . LYS B 1 361 ? 44.205  16.802  12.375  1 24.548 ? 353  LYS B C   1 
ATOM   6864 O  O   . LYS B 1 361 ? 43.224  17.495  12.091  1 25.97  ? 353  LYS B O   1 
ATOM   6865 C  CB  . LYS B 1 361 ? 46.336  16.662  10.994  1 20.629 ? 353  LYS B CB  1 
ATOM   6866 C  CG  . LYS B 1 361 ? 45.642  17.086  9.746   1 27.236 ? 353  LYS B CG  1 
ATOM   6867 C  CD  . LYS B 1 361 ? 46.086  16.114  8.667   1 24.963 ? 353  LYS B CD  1 
ATOM   6868 C  CE  . LYS B 1 361 ? 45.473  16.273  7.334   1 37.957 ? 353  LYS B CE  1 
ATOM   6869 N  NZ  . LYS B 1 361 ? 44.011  16.355  7.348   1 33.469 ? 353  LYS B NZ  1 
ATOM   6870 N  N   . GLN B 1 362 ? 44.092  15.589  12.92   1 27.672 ? 354  GLN B N   1 
ATOM   6871 C  CA  . GLN B 1 362 ? 42.815  15.061  13.41   1 22.738 ? 354  GLN B CA  1 
ATOM   6872 C  C   . GLN B 1 362 ? 42.108  16.09   14.305  1 27.359 ? 354  GLN B C   1 
ATOM   6873 O  O   . GLN B 1 362 ? 40.916  16.369  14.079  1 27.894 ? 354  GLN B O   1 
ATOM   6874 C  CB  . GLN B 1 362 ? 42.946  13.678  14.073  1 21.727 ? 354  GLN B CB  1 
ATOM   6875 C  CG  . GLN B 1 362 ? 41.583  13.077  14.486  1 20.394 ? 354  GLN B CG  1 
ATOM   6876 C  CD  . GLN B 1 362 ? 41.692  11.705  15.134  1 23.323 ? 354  GLN B CD  1 
ATOM   6877 O  OE1 . GLN B 1 362 ? 42.184  10.749  14.525  1 20.12  ? 354  GLN B OE1 1 
ATOM   6878 N  NE2 . GLN B 1 362 ? 41.404  11.626  16.428  1 21.41  ? 354  GLN B NE2 1 
ATOM   6879 N  N   . GLU B 1 363 ? 42.821  16.63   15.308  1 26.159 ? 355  GLU B N   1 
ATOM   6880 C  CA  . GLU B 1 363 ? 42.17   17.502  16.275  1 27.887 ? 355  GLU B CA  1 
ATOM   6881 C  C   . GLU B 1 363 ? 41.809  18.803  15.559  1 31.046 ? 355  GLU B C   1 
ATOM   6882 O  O   . GLU B 1 363 ? 40.681  19.288  15.71   1 30.839 ? 355  GLU B O   1 
ATOM   6883 C  CB  . GLU B 1 363 ? 42.96   17.776  17.552  1 24.815 ? 355  GLU B CB  1 
ATOM   6884 C  CG  . GLU B 1 363 ? 43.101  16.593  18.495  1 35.899 ? 355  GLU B CG  1 
ATOM   6885 C  CD  . GLU B 1 363 ? 42.164  16.655  19.698  1 49.304 ? 355  GLU B CD  1 
ATOM   6886 O  OE1 . GLU B 1 363 ? 42.604  17.027  20.842  1 38.353 ? 355  GLU B OE1 1 
ATOM   6887 O  OE2 . GLU B 1 363 ? 40.982  16.277  19.478  1 49.448 ? 355  GLU B OE2 1 
ATOM   6888 N  N   . ALA B 1 364 ? 42.735  19.289  14.718  1 30.088 ? 356  ALA B N   1 
ATOM   6889 C  CA  . ALA B 1 364 ? 42.53   20.494  13.908  1 39.489 ? 356  ALA B CA  1 
ATOM   6890 C  C   . ALA B 1 364 ? 41.25   20.397  13.081  1 40.028 ? 356  ALA B C   1 
ATOM   6891 O  O   . ALA B 1 364 ? 40.442  21.335  13.101  1 45.349 ? 356  ALA B O   1 
ATOM   6892 C  CB  . ALA B 1 364 ? 43.702  20.83   13.006  1 34.882 ? 356  ALA B CB  1 
ATOM   6893 N  N   . ASP B 1 365 ? 41.057  19.267  12.396  1 36.642 ? 357  ASP B N   1 
ATOM   6894 C  CA  . ASP B 1 365 ? 40.171  19.258  11.242  1 32.607 ? 357  ASP B CA  1 
ATOM   6895 C  C   . ASP B 1 365 ? 38.71   19      11.629  1 30.597 ? 357  ASP B C   1 
ATOM   6896 O  O   . ASP B 1 365 ? 37.843  18.961  10.748  1 26.384 ? 357  ASP B O   1 
ATOM   6897 C  CB  . ASP B 1 365 ? 40.675  18.359  10.14   1 38.669 ? 357  ASP B CB  1 
ATOM   6898 C  CG  . ASP B 1 365 ? 41.968  18.776  9.46    1 42.894 ? 357  ASP B CG  1 
ATOM   6899 O  OD1 . ASP B 1 365 ? 42.641  19.743  9.908   1 47.994 ? 357  ASP B OD1 1 
ATOM   6900 O  OD2 . ASP B 1 365 ? 42.297  18.112  8.482   1 43.534 ? 357  ASP B OD2 1 
ATOM   6901 N  N   . GLY B 1 366 ? 38.463  18.797  12.931  1 23.492 ? 358  GLY B N   1 
ATOM   6902 C  CA  . GLY B 1 366 ? 37.149  18.735  13.55   1 27.312 ? 358  GLY B CA  1 
ATOM   6903 C  C   . GLY B 1 366 ? 36.32   17.582  12.979  1 26.114 ? 358  GLY B C   1 
ATOM   6904 O  O   . GLY B 1 366 ? 36.9    16.57   12.595  1 26.494 ? 358  GLY B O   1 
ATOM   6905 N  N   . THR B 1 367 ? 34.978  17.755  12.902  1 22.488 ? 359  THR B N   1 
ATOM   6906 C  CA  . THR B 1 367 ? 34.081  16.751  12.356  1 21.879 ? 359  THR B CA  1 
ATOM   6907 C  C   . THR B 1 367 ? 34.302  16.666  10.843  1 22.523 ? 359  THR B C   1 
ATOM   6908 O  O   . THR B 1 367 ? 34.192  17.686  10.141  1 19.476 ? 359  THR B O   1 
ATOM   6909 C  CB  . THR B 1 367 ? 32.612  17.023  12.682  1 22.253 ? 359  THR B CB  1 
ATOM   6910 O  OG1 . THR B 1 367 ? 32.561  16.943  14.113  1 21.769 ? 359  THR B OG1 1 
ATOM   6911 C  CG2 . THR B 1 367 ? 31.683  15.954  12.099  1 18.12  ? 359  THR B CG2 1 
ATOM   6912 N  N   . PRO B 1 368 ? 34.674  15.466  10.311  1 21.258 ? 360  PRO B N   1 
ATOM   6913 C  CA  . PRO B 1 368 ? 34.882  15.311  8.872   1 18.543 ? 360  PRO B CA  1 
ATOM   6914 C  C   . PRO B 1 368 ? 33.633  15.527  8.033   1 19.2   ? 360  PRO B C   1 
ATOM   6915 O  O   . PRO B 1 368 ? 32.526  15.226  8.442   1 20.285 ? 360  PRO B O   1 
ATOM   6916 C  CB  . PRO B 1 368 ? 35.515  13.914  8.72    1 18.737 ? 360  PRO B CB  1 
ATOM   6917 C  CG  . PRO B 1 368 ? 36.047  13.578  10.132  1 17.716 ? 360  PRO B CG  1 
ATOM   6918 C  CD  . PRO B 1 368 ? 35.1    14.272  11.064  1 17.561 ? 360  PRO B CD  1 
ATOM   6919 N  N   . LYS B 1 369 ? 33.825  16.03   6.814   1 16.163 ? 361  LYS B N   1 
ATOM   6920 C  CA  . LYS B 1 369 ? 32.775  15.967  5.815   1 16.864 ? 361  LYS B CA  1 
ATOM   6921 C  C   . LYS B 1 369 ? 32.397  14.502  5.616   1 18.013 ? 361  LYS B C   1 
ATOM   6922 O  O   . LYS B 1 369 ? 33.32   13.683  5.532   1 19.611 ? 361  LYS B O   1 
ATOM   6923 C  CB  . LYS B 1 369 ? 33.404  16.485  4.502   1 14.601 ? 361  LYS B CB  1 
ATOM   6924 C  CG  . LYS B 1 369 ? 32.221  16.71   3.504   1 20.414 ? 361  LYS B CG  1 
ATOM   6925 C  CD  . LYS B 1 369 ? 32.581  17.445  2.212   1 20.765 ? 361  LYS B CD  1 
ATOM   6926 C  CE  . LYS B 1 369 ? 31.475  17.097  1.26    1 22.724 ? 361  LYS B CE  1 
ATOM   6927 N  NZ  . LYS B 1 369 ? 30.146  17.726  1.503   1 23.548 ? 361  LYS B NZ  1 
ATOM   6928 N  N   . ALA B 1 370 ? 31.093  14.205  5.417   1 18.738 ? 362  ALA B N   1 
ATOM   6929 C  CA  . ALA B 1 370 ? 30.603  12.848  5.194   1 17.124 ? 362  ALA B CA  1 
ATOM   6930 C  C   . ALA B 1 370 ? 29.513  12.831  4.126   1 16.259 ? 362  ALA B C   1 
ATOM   6931 O  O   . ALA B 1 370 ? 28.592  13.673  4.126   1 16.669 ? 362  ALA B O   1 
ATOM   6932 C  CB  . ALA B 1 370 ? 30.009  12.344  6.519   1 18.158 ? 362  ALA B CB  1 
ATOM   6933 N  N   . GLN B 1 371 ? 29.615  11.848  3.227   1 15.934 ? 363  GLN B N   1 
ATOM   6934 C  CA  . GLN B 1 371 ? 28.79   11.698  2.021   1 16.587 ? 363  GLN B CA  1 
ATOM   6935 C  C   . GLN B 1 371 ? 28.526  10.218  1.695   1 19.467 ? 363  GLN B C   1 
ATOM   6936 O  O   . GLN B 1 371 ? 29.026  9.336   2.388   1 18.027 ? 363  GLN B O   1 
ATOM   6937 C  CB  . GLN B 1 371 ? 29.438  12.268  0.756   1 16.482 ? 363  GLN B CB  1 
ATOM   6938 C  CG  . GLN B 1 371 ? 30.005  13.654  0.941   1 20.849 ? 363  GLN B CG  1 
ATOM   6939 C  CD  . GLN B 1 371 ? 30.713  14.09   -0.321  1 21.312 ? 363  GLN B CD  1 
ATOM   6940 O  OE1 . GLN B 1 371 ? 31.703  13.49   -0.74   1 25.113 ? 363  GLN B OE1 1 
ATOM   6941 N  NE2 . GLN B 1 371 ? 30.212  15.164  -0.907  1 27.693 ? 363  GLN B NE2 1 
ATOM   6942 N  N   . PHE B 1 372 ? 27.729  9.968   0.635   1 17.165 ? 364  PHE B N   1 
ATOM   6943 C  CA  . PHE B 1 372 ? 27.498  8.648   0.085   1 17.768 ? 364  PHE B CA  1 
ATOM   6944 C  C   . PHE B 1 372 ? 28.019  8.756   -1.35   1 17.633 ? 364  PHE B C   1 
ATOM   6945 O  O   . PHE B 1 372 ? 27.548  9.64    -2.068  1 16.937 ? 364  PHE B O   1 
ATOM   6946 C  CB  . PHE B 1 372 ? 26.019  8.291   0.171   1 16.765 ? 364  PHE B CB  1 
ATOM   6947 C  CG  . PHE B 1 372 ? 25.612  6.887   -0.232  1 20.339 ? 364  PHE B CG  1 
ATOM   6948 C  CD1 . PHE B 1 372 ? 25.865  5.806   0.615   1 20.739 ? 364  PHE B CD1 1 
ATOM   6949 C  CD2 . PHE B 1 372 ? 24.972  6.642   -1.467  1 19.176 ? 364  PHE B CD2 1 
ATOM   6950 C  CE1 . PHE B 1 372 ? 25.549  4.513   0.204   1 18.502 ? 364  PHE B CE1 1 
ATOM   6951 C  CE2 . PHE B 1 372 ? 24.613  5.347   -1.854  1 21.397 ? 364  PHE B CE2 1 
ATOM   6952 C  CZ  . PHE B 1 372 ? 24.91   4.294   -1.017  1 18.346 ? 364  PHE B CZ  1 
ATOM   6953 N  N   . VAL B 1 373 ? 28.909  7.812   -1.74   1 16.385 ? 365  VAL B N   1 
ATOM   6954 C  CA  . VAL B 1 373 ? 29.651  7.907   -3.015  1 16.685 ? 365  VAL B CA  1 
ATOM   6955 C  C   . VAL B 1 373 ? 29.583  6.617   -3.843  1 17.882 ? 365  VAL B C   1 
ATOM   6956 O  O   . VAL B 1 373 ? 29.321  5.552   -3.334  1 14.752 ? 365  VAL B O   1 
ATOM   6957 C  CB  . VAL B 1 373 ? 31.111  8.398   -2.828  1 19.258 ? 365  VAL B CB  1 
ATOM   6958 C  CG1 . VAL B 1 373 ? 31.179  9.744   -2.076  1 19.676 ? 365  VAL B CG1 1 
ATOM   6959 C  CG2 . VAL B 1 373 ? 31.965  7.33    -2.104  1 16.79  ? 365  VAL B CG2 1 
ATOM   6960 N  N   . ARG B 1 374 ? 29.752  6.731   -5.176  1 16.805 ? 366  ARG B N   1 
ATOM   6961 C  CA  . ARG B 1 374 ? 29.883  5.612   -6.094  1 16.609 ? 366  ARG B CA  1 
ATOM   6962 C  C   . ARG B 1 374 ? 31.303  5.555   -6.674  1 17.56  ? 366  ARG B C   1 
ATOM   6963 O  O   . ARG B 1 374 ? 31.771  6.514   -7.305  1 20.938 ? 366  ARG B O   1 
ATOM   6964 C  CB  . ARG B 1 374 ? 28.931  5.89    -7.272  1 18.566 ? 366  ARG B CB  1 
ATOM   6965 C  CG  . ARG B 1 374 ? 29.056  4.957   -8.459  1 19.18  ? 366  ARG B CG  1 
ATOM   6966 C  CD  . ARG B 1 374 ? 27.739  4.758   -9.242  1 21.895 ? 366  ARG B CD  1 
ATOM   6967 N  NE  . ARG B 1 374 ? 26.524  4.483   -8.453  1 21.685 ? 366  ARG B NE  1 
ATOM   6968 C  CZ  . ARG B 1 374 ? 25.349  5.15    -8.568  1 21.862 ? 366  ARG B CZ  1 
ATOM   6969 N  NH1 . ARG B 1 374 ? 24.941  5.759   -9.714  1 19.832 ? 366  ARG B NH1 1 
ATOM   6970 N  NH2 . ARG B 1 374 ? 24.507  5.104   -7.562  1 17.813 ? 366  ARG B NH2 1 
ATOM   6971 N  N   . TRP B 1 375 ? 31.947  4.388   -6.545  1 16.128 ? 367  TRP B N   1 
ATOM   6972 C  CA  . TRP B 1 375 ? 33.295  4.107   -7.027  1 16.885 ? 367  TRP B CA  1 
ATOM   6973 C  C   . TRP B 1 375 ? 33.237  3.328   -8.34   1 16.649 ? 367  TRP B C   1 
ATOM   6974 O  O   . TRP B 1 375 ? 32.367  2.471   -8.468  1 20.272 ? 367  TRP B O   1 
ATOM   6975 C  CB  . TRP B 1 375 ? 33.995  3.194   -6.031  1 14.712 ? 367  TRP B CB  1 
ATOM   6976 C  CG  . TRP B 1 375 ? 34.119  3.773   -4.635  1 14.562 ? 367  TRP B CG  1 
ATOM   6977 C  CD1 . TRP B 1 375 ? 33.267  3.533   -3.594  1 16.218 ? 367  TRP B CD1 1 
ATOM   6978 C  CD2 . TRP B 1 375 ? 35.143  4.657   -4.136  1 15.207 ? 367  TRP B CD2 1 
ATOM   6979 N  NE1 . TRP B 1 375 ? 33.688  4.208   -2.467  1 14.032 ? 367  TRP B NE1 1 
ATOM   6980 C  CE2 . TRP B 1 375 ? 34.839  4.896   -2.755  1 16.095 ? 367  TRP B CE2 1 
ATOM   6981 C  CE3 . TRP B 1 375 ? 36.299  5.257   -4.683  1 17.803 ? 367  TRP B CE3 1 
ATOM   6982 C  CZ2 . TRP B 1 375 ? 35.638  5.73    -1.957  1 18.926 ? 367  TRP B CZ2 1 
ATOM   6983 C  CZ3 . TRP B 1 375 ? 37.092  6.069   -3.887  1 17.62  ? 367  TRP B CZ3 1 
ATOM   6984 C  CH2 . TRP B 1 375 ? 36.76   6.303   -2.532  1 18.565 ? 367  TRP B CH2 1 
ATOM   6985 N  N   . THR B 1 376 ? 34.17   3.589   -9.253  1 17.009 ? 368  THR B N   1 
ATOM   6986 C  CA  . THR B 1 376 ? 34.311  2.82    -10.494 1 17.028 ? 368  THR B CA  1 
ATOM   6987 C  C   . THR B 1 376 ? 35.725  2.223   -10.584 1 17.045 ? 368  THR B C   1 
ATOM   6988 O  O   . THR B 1 376 ? 36.714  2.947   -10.681 1 17.451 ? 368  THR B O   1 
ATOM   6989 C  CB  . THR B 1 376 ? 33.946  3.632   -11.738 1 17.328 ? 368  THR B CB  1 
ATOM   6990 O  OG1 . THR B 1 376 ? 32.619  4.144   -11.677 1 19.655 ? 368  THR B OG1 1 
ATOM   6991 C  CG2 . THR B 1 376 ? 34.058  2.793   -13.011 1 21.219 ? 368  THR B CG2 1 
ATOM   6992 N  N   . ILE B 1 377 ? 35.798  0.879   -10.563 1 16.2   ? 369  ILE B N   1 
ATOM   6993 C  CA  . ILE B 1 377 ? 37.013  0.088   -10.726 1 14.629 ? 369  ILE B CA  1 
ATOM   6994 C  C   . ILE B 1 377 ? 36.867  -0.698  -12.028 1 16.482 ? 369  ILE B C   1 
ATOM   6995 O  O   . ILE B 1 377 ? 36.144  -1.704  -12.103 1 18.381 ? 369  ILE B O   1 
ATOM   6996 C  CB  . ILE B 1 377 ? 37.248  -0.86   -9.552  1 17.891 ? 369  ILE B CB  1 
ATOM   6997 C  CG1 . ILE B 1 377 ? 37.34   -0.017  -8.275  1 18.297 ? 369  ILE B CG1 1 
ATOM   6998 C  CG2 . ILE B 1 377 ? 38.577  -1.598  -9.797  1 21.621 ? 369  ILE B CG2 1 
ATOM   6999 C  CD1 . ILE B 1 377 ? 37.12   -0.716  -6.936  1 20.517 ? 369  ILE B CD1 1 
ATOM   7000 N  N   . ASP B 1 378 ? 37.446  -0.133  -13.075 1 14.262 ? 370  ASP B N   1 
ATOM   7001 C  CA  . ASP B 1 378 ? 37.382  -0.768  -14.386 1 13.887 ? 370  ASP B CA  1 
ATOM   7002 C  C   . ASP B 1 378 ? 38.534  -1.764  -14.513 1 14.526 ? 370  ASP B C   1 
ATOM   7003 O  O   . ASP B 1 378 ? 39.695  -1.352  -14.6   1 17.102 ? 370  ASP B O   1 
ATOM   7004 C  CB  . ASP B 1 378 ? 37.4    0.313   -15.469 1 15.506 ? 370  ASP B CB  1 
ATOM   7005 C  CG  . ASP B 1 378 ? 37.381  -0.187  -16.917 1 18.737 ? 370  ASP B CG  1 
ATOM   7006 O  OD1 . ASP B 1 378 ? 37.504  -1.446  -17.152 1 19.213 ? 370  ASP B OD1 1 
ATOM   7007 O  OD2 . ASP B 1 378 ? 37.247  0.696   -17.811 1 20.163 ? 370  ASP B OD2 1 
ATOM   7008 N  N   . PRO B 1 379 ? 38.303  -3.103  -14.503 1 17.683 ? 371  PRO B N   1 
ATOM   7009 C  CA  . PRO B 1 379 ? 39.404  -4.068  -14.533 1 20.678 ? 371  PRO B CA  1 
ATOM   7010 C  C   . PRO B 1 379 ? 40.187  -4.154  -15.85  1 22.699 ? 371  PRO B C   1 
ATOM   7011 O  O   . PRO B 1 379 ? 41.196  -4.879  -15.926 1 20.668 ? 371  PRO B O   1 
ATOM   7012 C  CB  . PRO B 1 379 ? 38.71   -5.41   -14.16  1 23.931 ? 371  PRO B CB  1 
ATOM   7013 C  CG  . PRO B 1 379 ? 37.246  -5.213  -14.46  1 19.819 ? 371  PRO B CG  1 
ATOM   7014 C  CD  . PRO B 1 379 ? 36.974  -3.741  -14.47  1 16.67  ? 371  PRO B CD  1 
ATOM   7015 N  N   . ARG B 1 380 ? 39.748  -3.412  -16.879 1 24.024 ? 372  ARG B N   1 
ATOM   7016 C  CA  . ARG B 1 380 ? 40.523  -3.326  -18.125 1 25.766 ? 372  ARG B CA  1 
ATOM   7017 C  C   . ARG B 1 380 ? 41.723  -2.36   -17.976 1 28.164 ? 372  ARG B C   1 
ATOM   7018 O  O   . ARG B 1 380 ? 42.741  -2.427  -18.691 1 30.71  ? 372  ARG B O   1 
ATOM   7019 C  CB  . ARG B 1 380 ? 39.622  -2.895  -19.285 1 22.023 ? 372  ARG B CB  1 
ATOM   7020 C  CG  . ARG B 1 380 ? 38.604  -3.957  -19.652 1 24.988 ? 372  ARG B CG  1 
ATOM   7021 C  CD  . ARG B 1 380 ? 37.522  -3.309  -20.504 1 29.923 ? 372  ARG B CD  1 
ATOM   7022 N  NE  . ARG B 1 380 ? 36.885  -2.103  -19.938 1 29.749 ? 372  ARG B NE  1 
ATOM   7023 C  CZ  . ARG B 1 380 ? 35.912  -1.372  -20.477 1 32.628 ? 372  ARG B CZ  1 
ATOM   7024 N  NH1 . ARG B 1 380 ? 35.426  -1.638  -21.686 1 34.455 ? 372  ARG B NH1 1 
ATOM   7025 N  NH2 . ARG B 1 380 ? 35.47   -0.315  -19.822 1 39.527 ? 372  ARG B NH2 1 
ATOM   7026 N  N   . LYS B 1 381 ? 41.653  -1.495  -16.964 1 21.996 ? 373  LYS B N   1 
ATOM   7027 C  CA  . LYS B 1 381 ? 42.647  -0.462  -16.767 1 25.768 ? 373  LYS B CA  1 
ATOM   7028 C  C   . LYS B 1 381 ? 43.786  -1.009  -15.919 1 24.173 ? 373  LYS B C   1 
ATOM   7029 O  O   . LYS B 1 381 ? 43.625  -2.009  -15.249 1 25.079 ? 373  LYS B O   1 
ATOM   7030 C  CB  . LYS B 1 381 ? 41.981  0.728   -16.071 1 27.503 ? 373  LYS B CB  1 
ATOM   7031 C  CG  . LYS B 1 381 ? 41.039  1.523   -16.959 1 21.733 ? 373  LYS B CG  1 
ATOM   7032 C  CD  . LYS B 1 381 ? 40.642  2.869   -16.362 1 26.438 ? 373  LYS B CD  1 
ATOM   7033 C  CE  . LYS B 1 381 ? 41.751  3.886   -16.363 1 33.521 ? 373  LYS B CE  1 
ATOM   7034 N  NZ  . LYS B 1 381 ? 42.208  4.332   -17.699 1 41.348 ? 373  LYS B NZ  1 
ATOM   7035 N  N   . ASP B 1 382 ? 44.936  -0.362  -16.043 1 24.569 ? 374  ASP B N   1 
ATOM   7036 C  CA  . ASP B 1 382 ? 46.109  -0.608  -15.235 1 25.191 ? 374  ASP B CA  1 
ATOM   7037 C  C   . ASP B 1 382 ? 45.803  -0.233  -13.781 1 22.945 ? 374  ASP B C   1 
ATOM   7038 O  O   . ASP B 1 382 ? 45.542  0.917   -13.496 1 18.806 ? 374  ASP B O   1 
ATOM   7039 C  CB  . ASP B 1 382 ? 47.305  0.14    -15.817 1 30.335 ? 374  ASP B CB  1 
ATOM   7040 C  CG  . ASP B 1 382 ? 48.615  -0.018  -15.071 1 32.915 ? 374  ASP B CG  1 
ATOM   7041 O  OD1 . ASP B 1 382 ? 48.632  -0.696  -13.994 1 30.04  ? 374  ASP B OD1 1 
ATOM   7042 O  OD2 . ASP B 1 382 ? 49.633  0.551   -15.572 1 39.917 ? 374  ASP B OD2 1 
ATOM   7043 N  N   . ASN B 1 383 ? 45.881  -1.221  -12.885 1 22.999 ? 375  ASN B N   1 
ATOM   7044 C  CA  . ASN B 1 383 ? 45.605  -1      -11.471 1 25.585 ? 375  ASN B CA  1 
ATOM   7045 C  C   . ASN B 1 383 ? 46.644  -0.108  -10.788 1 29.238 ? 375  ASN B C   1 
ATOM   7046 O  O   . ASN B 1 383 ? 46.404  0.317   -9.651  1 23.133 ? 375  ASN B O   1 
ATOM   7047 C  CB  . ASN B 1 383 ? 45.401  -2.307  -10.711 1 24.324 ? 375  ASN B CB  1 
ATOM   7048 C  CG  . ASN B 1 383 ? 46.641  -3.149  -10.713 1 24.221 ? 375  ASN B CG  1 
ATOM   7049 O  OD1 . ASN B 1 383 ? 47.039  -3.607  -11.785 1 22.237 ? 375  ASN B OD1 1 
ATOM   7050 N  ND2 . ASN B 1 383 ? 47.204  -3.394  -9.543  1 19.911 ? 375  ASN B ND2 1 
ATOM   7051 N  N   . ASN B 1 384 ? 47.817  0.106   -11.435 1 28.406 ? 376  ASN B N   1 
ATOM   7052 C  CA  . ASN B 1 384 ? 48.805  1.067   -10.95  1 28.703 ? 376  ASN B CA  1 
ATOM   7053 C  C   . ASN B 1 384 ? 48.364  2.529   -11.092 1 27.37  ? 376  ASN B C   1 
ATOM   7054 O  O   . ASN B 1 384 ? 48.962  3.427   -10.493 1 24.481 ? 376  ASN B O   1 
ATOM   7055 C  CB  . ASN B 1 384 ? 50.223  0.793   -11.457 1 25.21  ? 376  ASN B CB  1 
ATOM   7056 C  CG  . ASN B 1 384 ? 50.676  -0.58   -11.038 1 31.845 ? 376  ASN B CG  1 
ATOM   7057 O  OD1 . ASN B 1 384 ? 51.094  -1.373  -11.888 1 45.706 ? 376  ASN B OD1 1 
ATOM   7058 N  ND2 . ASN B 1 384 ? 50.672  -0.853  -9.741  1 22.913 ? 376  ASN B ND2 1 
ATOM   7059 N  N   . GLU B 1 385 ? 47.358  2.785   -11.929 1 28.187 ? 377  GLU B N   1 
ATOM   7060 C  CA  . GLU B 1 385 ? 46.855  4.138   -12.107 1 29.068 ? 377  GLU B CA  1 
ATOM   7061 C  C   . GLU B 1 385 ? 45.896  4.437   -10.957 1 25.621 ? 377  GLU B C   1 
ATOM   7062 O  O   . GLU B 1 385 ? 45.045  3.613   -10.667 1 23.352 ? 377  GLU B O   1 
ATOM   7063 C  CB  . GLU B 1 385 ? 46.272  4.254   -13.509 1 24.126 ? 377  GLU B CB  1 
ATOM   7064 C  CG  . GLU B 1 385 ? 45.62   5.588   -13.825 1 29.197 ? 377  GLU B CG  1 
ATOM   7065 C  CD  . GLU B 1 385 ? 45.15   5.579   -15.266 1 40.184 ? 377  GLU B CD  1 
ATOM   7066 O  OE1 . GLU B 1 385 ? 45.936  5.294   -16.21  1 41.109 ? 377  GLU B OE1 1 
ATOM   7067 O  OE2 . GLU B 1 385 ? 43.945  5.865   -15.417 1 36.742 ? 377  GLU B OE2 1 
ATOM   7068 N  N   . GLN B 1 386 ? 45.99   5.642   -10.395 1 23.328 ? 378  GLN B N   1 
ATOM   7069 C  CA  . GLN B 1 386 ? 45.026  6.109   -9.412  1 24.101 ? 378  GLN B CA  1 
ATOM   7070 C  C   . GLN B 1 386 ? 43.606  6.007   -9.955  1 22.091 ? 378  GLN B C   1 
ATOM   7071 O  O   . GLN B 1 386 ? 43.296  6.38    -11.094 1 21.714 ? 378  GLN B O   1 
ATOM   7072 C  CB  . GLN B 1 386 ? 45.338  7.523   -8.938  1 24.911 ? 378  GLN B CB  1 
ATOM   7073 C  CG  . GLN B 1 386 ? 44.513  8.024   -7.759  1 26.847 ? 378  GLN B CG  1 
ATOM   7074 C  CD  . GLN B 1 386 ? 45.115  9.282   -7.159  1 34.325 ? 378  GLN B CD  1 
ATOM   7075 O  OE1 . GLN B 1 386 ? 45.301  10.282  -7.851  1 33.143 ? 378  GLN B OE1 1 
ATOM   7076 N  NE2 . GLN B 1 386 ? 45.459  9.261   -5.871  1 34.66  ? 378  GLN B NE2 1 
ATOM   7077 N  N   . LEU B 1 387 ? 42.716  5.474   -9.103  1 19.742 ? 379  LEU B N   1 
ATOM   7078 C  CA  . LEU B 1 387 ? 41.295  5.409   -9.412  1 18.505 ? 379  LEU B CA  1 
ATOM   7079 C  C   . LEU B 1 387 ? 40.711  6.795   -9.729  1 16.03  ? 379  LEU B C   1 
ATOM   7080 O  O   . LEU B 1 387 ? 41.194  7.796   -9.195  1 15.474 ? 379  LEU B O   1 
ATOM   7081 C  CB  . LEU B 1 387 ? 40.512  4.717   -8.28   1 18.363 ? 379  LEU B CB  1 
ATOM   7082 C  CG  . LEU B 1 387 ? 40.654  3.195   -8.196  1 20.493 ? 379  LEU B CG  1 
ATOM   7083 C  CD1 . LEU B 1 387 ? 39.964  2.771   -6.883  1 20.155 ? 379  LEU B CD1 1 
ATOM   7084 C  CD2 . LEU B 1 387 ? 40.027  2.563   -9.462  1 20.073 ? 379  LEU B CD2 1 
ATOM   7085 N  N   . PRO B 1 388 ? 39.647  6.874   -10.565 1 17.697 ? 380  PRO B N   1 
ATOM   7086 C  CA  . PRO B 1 388 ? 38.847  8.102   -10.669 1 21.118 ? 380  PRO B CA  1 
ATOM   7087 C  C   . PRO B 1 388 ? 38.168  8.482   -9.357  1 24.781 ? 380  PRO B C   1 
ATOM   7088 O  O   . PRO B 1 388 ? 37.915  7.634   -8.493  1 23.104 ? 380  PRO B O   1 
ATOM   7089 C  CB  . PRO B 1 388 ? 37.852  7.872   -11.806 1 19.555 ? 380  PRO B CB  1 
ATOM   7090 C  CG  . PRO B 1 388 ? 37.786  6.356   -11.872 1 22.337 ? 380  PRO B CG  1 
ATOM   7091 C  CD  . PRO B 1 388 ? 39.077  5.772   -11.365 1 19.124 ? 380  PRO B CD  1 
ATOM   7092 N  N   . ASP B 1 389 ? 37.952  9.798   -9.191  1 25.919 ? 381  ASP B N   1 
ATOM   7093 C  CA  . ASP B 1 389 ? 37.269  10.321  -8.017  1 20.566 ? 381  ASP B CA  1 
ATOM   7094 C  C   . ASP B 1 389 ? 35.882  9.7     -7.972  1 19.608 ? 381  ASP B C   1 
ATOM   7095 O  O   . ASP B 1 389 ? 35.263  9.516   -9.023  1 20.481 ? 381  ASP B O   1 
ATOM   7096 C  CB  . ASP B 1 389 ? 37.175  11.847  -8.007  1 22.333 ? 381  ASP B CB  1 
ATOM   7097 C  CG  . ASP B 1 389 ? 38.488  12.586  -7.869  1 23.008 ? 381  ASP B CG  1 
ATOM   7098 O  OD1 . ASP B 1 389 ? 39.534  11.93   -7.656  1 20.657 ? 381  ASP B OD1 1 
ATOM   7099 O  OD2 . ASP B 1 389 ? 38.447  13.812  -8.054  1 27.512 ? 381  ASP B OD2 1 
ATOM   7100 N  N   . PRO B 1 390 ? 35.349  9.339   -6.77   1 20.684 ? 382  PRO B N   1 
ATOM   7101 C  CA  . PRO B 1 390 ? 34.018  8.748   -6.709  1 21.799 ? 382  PRO B CA  1 
ATOM   7102 C  C   . PRO B 1 390 ? 32.914  9.768   -6.965  1 20.687 ? 382  PRO B C   1 
ATOM   7103 O  O   . PRO B 1 390 ? 33.159  10.95   -6.786  1 23.413 ? 382  PRO B O   1 
ATOM   7104 C  CB  . PRO B 1 390 ? 33.99   8.114   -5.324  1 21.684 ? 382  PRO B CB  1 
ATOM   7105 C  CG  . PRO B 1 390 ? 34.861  9.057   -4.501  1 19.666 ? 382  PRO B CG  1 
ATOM   7106 C  CD  . PRO B 1 390 ? 36.002  9.465   -5.445  1 20.285 ? 382  PRO B CD  1 
ATOM   7107 N  N   . GLU B 1 391 ? 31.745  9.308   -7.429  1 20.854 ? 383  GLU B N   1 
ATOM   7108 C  CA  . GLU B 1 391 ? 30.658  10.234  -7.699  1 22.072 ? 383  GLU B CA  1 
ATOM   7109 C  C   . GLU B 1 391 ? 29.879  10.463  -6.412  1 25.592 ? 383  GLU B C   1 
ATOM   7110 O  O   . GLU B 1 391 ? 29.658  9.499   -5.676  1 23.79  ? 383  GLU B O   1 
ATOM   7111 C  CB  . GLU B 1 391 ? 29.869  9.727   -8.896  1 21.648 ? 383  GLU B CB  1 
ATOM   7112 C  CG  . GLU B 1 391 ? 28.731  10.658  -9.304  1 26.211 ? 383  GLU B CG  1 
ATOM   7113 C  CD  . GLU B 1 391 ? 27.743  10.052  -10.294 1 33.953 ? 383  GLU B CD  1 
ATOM   7114 O  OE1 . GLU B 1 391 ? 27.872  8.901   -10.805 1 34.905 ? 383  GLU B OE1 1 
ATOM   7115 O  OE2 . GLU B 1 391 ? 26.775  10.781  -10.543 1 37.653 ? 383  GLU B OE2 1 
ATOM   7116 N  N   . VAL B 1 392 ? 29.501  11.72   -6.149  1 24.092 ? 384  VAL B N   1 
ATOM   7117 C  CA  . VAL B 1 392 ? 28.658  12.045  -5.011  1 24.249 ? 384  VAL B CA  1 
ATOM   7118 C  C   . VAL B 1 392 ? 27.2    11.697  -5.353  1 26.7   ? 384  VAL B C   1 
ATOM   7119 O  O   . VAL B 1 392 ? 26.628  12.196  -6.358  1 22.215 ? 384  VAL B O   1 
ATOM   7120 C  CB  . VAL B 1 392 ? 28.86   13.456  -4.422  1 27.162 ? 384  VAL B CB  1 
ATOM   7121 C  CG1 . VAL B 1 392 ? 27.954  13.72   -3.209  1 26.707 ? 384  VAL B CG1 1 
ATOM   7122 C  CG2 . VAL B 1 392 ? 30.327  13.702  -4.045  1 25.925 ? 384  VAL B CG2 1 
ATOM   7123 N  N   . ILE B 1 393 ? 26.655  10.74   -4.573  1 20.509 ? 385  ILE B N   1 
ATOM   7124 C  CA  . ILE B 1 393 ? 25.279  10.249  -4.718  1 18.712 ? 385  ILE B CA  1 
ATOM   7125 C  C   . ILE B 1 393 ? 24.37   10.973  -3.732  1 22.07  ? 385  ILE B C   1 
ATOM   7126 O  O   . ILE B 1 393 ? 23.363  11.52   -4.135  1 16.994 ? 385  ILE B O   1 
ATOM   7127 C  CB  . ILE B 1 393 ? 25.178  8.696   -4.644  1 17.761 ? 385  ILE B CB  1 
ATOM   7128 C  CG1 . ILE B 1 393 ? 26.041  7.969   -5.747  1 20.456 ? 385  ILE B CG1 1 
ATOM   7129 C  CG2 . ILE B 1 393 ? 23.727  8.228   -4.67   1 16.694 ? 385  ILE B CG2 1 
ATOM   7130 C  CD1 . ILE B 1 393 ? 25.685  8.326   -7.209  1 24.188 ? 385  ILE B CD1 1 
ATOM   7131 N  N   . LEU B 1 394 ? 24.765  10.991  -2.446  1 20.111 ? 386  LEU B N   1 
ATOM   7132 C  CA  . LEU B 1 394 ? 24.066  11.752  -1.441  1 20.915 ? 386  LEU B CA  1 
ATOM   7133 C  C   . LEU B 1 394 ? 25.088  12.645  -0.748  1 23.678 ? 386  LEU B C   1 
ATOM   7134 O  O   . LEU B 1 394 ? 26.129  12.206  -0.209  1 18.919 ? 386  LEU B O   1 
ATOM   7135 C  CB  . LEU B 1 394 ? 23.306  10.915  -0.408  1 23.603 ? 386  LEU B CB  1 
ATOM   7136 C  CG  . LEU B 1 394 ? 22.322  9.855   -0.922  1 24.648 ? 386  LEU B CG  1 
ATOM   7137 C  CD1 . LEU B 1 394 ? 21.85   9.222   0.392   1 26.169 ? 386  LEU B CD1 1 
ATOM   7138 C  CD2 . LEU B 1 394 ? 21.102  10.446  -1.666  1 22.935 ? 386  LEU B CD2 1 
ATOM   7139 N  N   . ASP B 1 395 ? 24.737  13.927  -0.764  1 19.583 ? 387  ASP B N   1 
ATOM   7140 C  CA  . ASP B 1 395 ? 25.642  14.878  -0.192  1 20.224 ? 387  ASP B CA  1 
ATOM   7141 C  C   . ASP B 1 395 ? 25.276  15.127  1.246   1 19.33  ? 387  ASP B C   1 
ATOM   7142 O  O   . ASP B 1 395 ? 25.084  16.281  1.635   1 20.679 ? 387  ASP B O   1 
ATOM   7143 C  CB  . ASP B 1 395 ? 25.716  16.164  -0.993  1 22.084 ? 387  ASP B CB  1 
ATOM   7144 C  CG  . ASP B 1 395 ? 26.975  16.984  -0.705  1 25.197 ? 387  ASP B CG  1 
ATOM   7145 O  OD1 . ASP B 1 395 ? 27.989  16.446  -0.095  1 24.5   ? 387  ASP B OD1 1 
ATOM   7146 O  OD2 . ASP B 1 395 ? 26.919  18.172  -1.043  1 26.045 ? 387  ASP B OD2 1 
ATOM   7147 N  N   . THR B 1 396 ? 25.151  14.035  2.023   1 18.992 ? 388  THR B N   1 
ATOM   7148 C  CA  . THR B 1 396 ? 24.867  14.23   3.431   1 16.285 ? 388  THR B CA  1 
ATOM   7149 C  C   . THR B 1 396 ? 25.501  13.091  4.191   1 17.748 ? 388  THR B C   1 
ATOM   7150 O  O   . THR B 1 396 ? 25.773  12.038  3.603   1 16.255 ? 388  THR B O   1 
ATOM   7151 C  CB  . THR B 1 396 ? 23.331  14.26   3.644   1 23.791 ? 388  THR B CB  1 
ATOM   7152 O  OG1 . THR B 1 396 ? 22.986  14.889  4.888   1 22.451 ? 388  THR B OG1 1 
ATOM   7153 C  CG2 . THR B 1 396 ? 22.557  12.948  3.504   1 25.255 ? 388  THR B CG2 1 
ATOM   7154 N  N   . PRO B 1 397 ? 25.746  13.249  5.511   1 17.927 ? 389  PRO B N   1 
ATOM   7155 C  CA  . PRO B 1 397 ? 26.233  12.122  6.3     1 16.315 ? 389  PRO B CA  1 
ATOM   7156 C  C   . PRO B 1 397 ? 25.305  10.917  6.187   1 17.148 ? 389  PRO B C   1 
ATOM   7157 O  O   . PRO B 1 397 ? 24.1    11.054  6.362   1 18.869 ? 389  PRO B O   1 
ATOM   7158 C  CB  . PRO B 1 397 ? 26.362  12.675  7.717   1 16.378 ? 389  PRO B CB  1 
ATOM   7159 C  CG  . PRO B 1 397 ? 26.487  14.168  7.492   1 20.529 ? 389  PRO B CG  1 
ATOM   7160 C  CD  . PRO B 1 397 ? 25.617  14.484  6.295   1 16.857 ? 389  PRO B CD  1 
ATOM   7161 N  N   . SER B 1 398 ? 25.91   9.76    5.851   1 15.688 ? 390  SER B N   1 
ATOM   7162 C  CA  . SER B 1 398 ? 25.243  8.549   5.447   1 15.693 ? 390  SER B CA  1 
ATOM   7163 C  C   . SER B 1 398 ? 26.02   7.382   6.036   1 13.46  ? 390  SER B C   1 
ATOM   7164 O  O   . SER B 1 398 ? 27.229  7.413   6.065   1 13.685 ? 390  SER B O   1 
ATOM   7165 C  CB  . SER B 1 398 ? 25.306  8.419   3.912   1 15.343 ? 390  SER B CB  1 
ATOM   7166 O  OG  . SER B 1 398 ? 24.566  9.498   3.405   1 19.841 ? 390  SER B OG  1 
ATOM   7167 N  N   . GLU B 1 399 ? 25.282  6.387   6.541   1 17.347 ? 391  GLU B N   1 
ATOM   7168 C  CA  . GLU B 1 399 ? 25.914  5.204   7.101   1 15.398 ? 391  GLU B CA  1 
ATOM   7169 C  C   . GLU B 1 399 ? 24.938  4.031   7.121   1 12.665 ? 391  GLU B C   1 
ATOM   7170 O  O   . GLU B 1 399 ? 23.799  4.137   6.654   1 14.127 ? 391  GLU B O   1 
ATOM   7171 C  CB  . GLU B 1 399 ? 26.657  5.452   8.434   1 14.426 ? 391  GLU B CB  1 
ATOM   7172 C  CG  . GLU B 1 399 ? 28.177  5.31    8.29    1 14.775 ? 391  GLU B CG  1 
ATOM   7173 C  CD  . GLU B 1 399 ? 28.535  3.904   7.852   1 17.058 ? 391  GLU B CD  1 
ATOM   7174 O  OE1 . GLU B 1 399 ? 28.141  3.017   8.576   1 19.062 ? 391  GLU B OE1 1 
ATOM   7175 O  OE2 . GLU B 1 399 ? 28.947  3.686   6.725   1 19.576 ? 391  GLU B OE2 1 
ATOM   7176 N  N   . PHE B 1 400 ? 25.477  2.868   7.521   1 13.868 ? 392  PHE B N   1 
ATOM   7177 C  CA  . PHE B 1 400 ? 24.752  1.589   7.609   1 12.755 ? 392  PHE B CA  1 
ATOM   7178 C  C   . PHE B 1 400 ? 23.763  1.412   6.459   1 11.91  ? 392  PHE B C   1 
ATOM   7179 O  O   . PHE B 1 400 ? 22.545  1.301   6.67    1 12.842 ? 392  PHE B O   1 
ATOM   7180 C  CB  . PHE B 1 400 ? 23.976  1.664   8.922   1 14.45  ? 392  PHE B CB  1 
ATOM   7181 C  CG  . PHE B 1 400 ? 24.889  1.597   10.139  1 16.811 ? 392  PHE B CG  1 
ATOM   7182 C  CD1 . PHE B 1 400 ? 25.657  0.453   10.36   1 16.418 ? 392  PHE B CD1 1 
ATOM   7183 C  CD2 . PHE B 1 400 ? 24.968  2.649   11.067  1 15.398 ? 392  PHE B CD2 1 
ATOM   7184 C  CE1 . PHE B 1 400 ? 26.387  0.306   11.526  1 16.35  ? 392  PHE B CE1 1 
ATOM   7185 C  CE2 . PHE B 1 400 ? 25.697  2.498   12.237  1 15.796 ? 392  PHE B CE2 1 
ATOM   7186 C  CZ  . PHE B 1 400 ? 26.425  1.328   12.45   1 16.936 ? 392  PHE B CZ  1 
ATOM   7187 N  N   . PRO B 1 401 ? 24.26   1.421   5.198   1 12.961 ? 393  PRO B N   1 
ATOM   7188 C  CA  . PRO B 1 401 ? 23.408  1.12    4.056   1 11.692 ? 393  PRO B CA  1 
ATOM   7189 C  C   . PRO B 1 401 ? 23.094  -0.377  3.928   1 11.846 ? 393  PRO B C   1 
ATOM   7190 O  O   . PRO B 1 401 ? 23.989  -1.208  4.189   1 13.518 ? 393  PRO B O   1 
ATOM   7191 C  CB  . PRO B 1 401 ? 24.275  1.53    2.907   1 12.715 ? 393  PRO B CB  1 
ATOM   7192 C  CG  . PRO B 1 401 ? 25.715  1.41    3.345   1 13.003 ? 393  PRO B CG  1 
ATOM   7193 C  CD  . PRO B 1 401 ? 25.671  1.659   4.842   1 13.403 ? 393  PRO B CD  1 
ATOM   7194 N  N   . GLN B 1 402 ? 21.857  -0.715  3.515   1 13.04  ? 394  GLN B N   1 
ATOM   7195 C  CA  . GLN B 1 402 ? 21.549  -2.068  3.105   1 13.862 ? 394  GLN B CA  1 
ATOM   7196 C  C   . GLN B 1 402 ? 20.844  -2.027  1.756   1 16.081 ? 394  GLN B C   1 
ATOM   7197 O  O   . GLN B 1 402 ? 20.466  -0.932  1.291   1 15.213 ? 394  GLN B O   1 
ATOM   7198 C  CB  . GLN B 1 402 ? 20.672  -2.795  4.104   1 14.649 ? 394  GLN B CB  1 
ATOM   7199 C  CG  . GLN B 1 402 ? 21.335  -3.047  5.457   1 18.325 ? 394  GLN B CG  1 
ATOM   7200 C  CD  . GLN B 1 402 ? 20.855  -4.312  6.138   1 18.784 ? 394  GLN B CD  1 
ATOM   7201 O  OE1 . GLN B 1 402 ? 19.879  -4.96   5.701   1 20.32  ? 394  GLN B OE1 1 
ATOM   7202 N  NE2 . GLN B 1 402 ? 21.535  -4.702  7.232   1 16.222 ? 394  GLN B NE2 1 
ATOM   7203 N  N   . ILE B 1 403 ? 20.724  -3.199  1.141   1 14.878 ? 395  ILE B N   1 
ATOM   7204 C  CA  . ILE B 1 403 ? 20.021  -3.28   -0.142  1 17.039 ? 395  ILE B CA  1 
ATOM   7205 C  C   . ILE B 1 403 ? 18.805  -4.226  -0.074  1 15.977 ? 395  ILE B C   1 
ATOM   7206 O  O   . ILE B 1 403 ? 18.426  -4.683  1.023   1 16.374 ? 395  ILE B O   1 
ATOM   7207 C  CB  . ILE B 1 403 ? 20.989  -3.613  -1.297  1 14.717 ? 395  ILE B CB  1 
ATOM   7208 C  CG1 . ILE B 1 403 ? 21.592  -5.051  -1.175  1 14.942 ? 395  ILE B CG1 1 
ATOM   7209 C  CG2 . ILE B 1 403 ? 22.068  -2.519  -1.407  1 15.425 ? 395  ILE B CG2 1 
ATOM   7210 C  CD1 . ILE B 1 403 ? 21.941  -5.705  -2.515  1 20.054 ? 395  ILE B CD1 1 
ATOM   7211 N  N   . ASP B 1 404 ? 18.201  -4.48   -1.274  1 17.352 ? 396  ASP B N   1 
ATOM   7212 C  CA  . ASP B 1 404 ? 17.274  -5.592  -1.439  1 19.813 ? 396  ASP B CA  1 
ATOM   7213 C  C   . ASP B 1 404 ? 18.145  -6.812  -1.721  1 18.416 ? 396  ASP B C   1 
ATOM   7214 O  O   . ASP B 1 404 ? 18.652  -6.95   -2.828  1 19.914 ? 396  ASP B O   1 
ATOM   7215 C  CB  . ASP B 1 404 ? 16.182  -5.305  -2.484  1 19.694 ? 396  ASP B CB  1 
ATOM   7216 C  CG  . ASP B 1 404 ? 15.136  -6.392  -2.752  1 21.249 ? 396  ASP B CG  1 
ATOM   7217 O  OD1 . ASP B 1 404 ? 15.327  -7.585  -2.35   1 18.377 ? 396  ASP B OD1 1 
ATOM   7218 O  OD2 . ASP B 1 404 ? 14.122  -6.057  -3.437  1 22.491 ? 396  ASP B OD2 1 
ATOM   7219 N  N   . ASN B 1 405 ? 18.296  -7.699  -0.733  1 19.158 ? 397  ASN B N   1 
ATOM   7220 C  CA  . ASN B 1 405 ? 19.272  -8.794  -0.861  1 18.379 ? 397  ASN B CA  1 
ATOM   7221 C  C   . ASN B 1 405 ? 18.93   -9.835  -1.923  1 16.697 ? 397  ASN B C   1 
ATOM   7222 O  O   . ASN B 1 405 ? 19.785  -10.628 -2.261  1 16.949 ? 397  ASN B O   1 
ATOM   7223 C  CB  . ASN B 1 405 ? 19.384  -9.561  0.434   1 18.137 ? 397  ASN B CB  1 
ATOM   7224 C  CG  . ASN B 1 405 ? 20.166  -8.738  1.404   1 21.382 ? 397  ASN B CG  1 
ATOM   7225 O  OD1 . ASN B 1 405 ? 20.011  -9.006  2.591   1 23.434 ? 397  ASN B OD1 1 
ATOM   7226 N  ND2 . ASN B 1 405 ? 20.931  -7.76   0.936   1 17.512 ? 397  ASN B ND2 1 
ATOM   7227 N  N   . ARG B 1 406 ? 17.717  -9.824  -2.484  1 19.1   ? 398  ARG B N   1 
ATOM   7228 C  CA  . ARG B 1 406 ? 17.457  -10.654 -3.661  1 22.763 ? 398  ARG B CA  1 
ATOM   7229 C  C   . ARG B 1 406 ? 18.332  -10.217 -4.859  1 24.418 ? 398  ARG B C   1 
ATOM   7230 O  O   . ARG B 1 406 ? 18.327  -10.853 -5.938  1 21.266 ? 398  ARG B O   1 
ATOM   7231 C  CB  . ARG B 1 406 ? 15.973  -10.507 -3.993  1 21.502 ? 398  ARG B CB  1 
ATOM   7232 C  CG  . ARG B 1 406 ? 15.03   -11.177 -3.009  1 22.639 ? 398  ARG B CG  1 
ATOM   7233 C  CD  . ARG B 1 406 ? 13.576  -10.807 -3.378  1 21.747 ? 398  ARG B CD  1 
ATOM   7234 N  NE  . ARG B 1 406 ? 13.295  -9.362  -3.512  1 19.564 ? 398  ARG B NE  1 
ATOM   7235 C  CZ  . ARG B 1 406 ? 12.179  -8.844  -4.028  1 18.099 ? 398  ARG B CZ  1 
ATOM   7236 N  NH1 . ARG B 1 406 ? 11.202  -9.656  -4.436  1 19.757 ? 398  ARG B NH1 1 
ATOM   7237 N  NH2 . ARG B 1 406 ? 12.028  -7.541  -4.173  1 17.998 ? 398  ARG B NH2 1 
ATOM   7238 N  N   . PHE B 1 407 ? 19.071  -9.115  -4.674  1 23.577 ? 399  PHE B N   1 
ATOM   7239 C  CA  . PHE B 1 407 ? 19.924  -8.509  -5.703  1 20.785 ? 399  PHE B CA  1 
ATOM   7240 C  C   . PHE B 1 407 ? 21.373  -8.481  -5.258  1 18.477 ? 399  PHE B C   1 
ATOM   7241 O  O   . PHE B 1 407 ? 22.229  -7.863  -5.931  1 19.906 ? 399  PHE B O   1 
ATOM   7242 C  CB  . PHE B 1 407 ? 19.385  -7.167  -6.199  1 21.534 ? 399  PHE B CB  1 
ATOM   7243 C  CG  . PHE B 1 407 ? 18.006  -7.284  -6.833  1 21.034 ? 399  PHE B CG  1 
ATOM   7244 C  CD1 . PHE B 1 407 ? 16.851  -7.339  -6.048  1 21.973 ? 399  PHE B CD1 1 
ATOM   7245 C  CD2 . PHE B 1 407 ? 17.865  -7.412  -8.22   1 24.743 ? 399  PHE B CD2 1 
ATOM   7246 C  CE1 . PHE B 1 407 ? 15.578  -7.461  -6.587  1 23.199 ? 399  PHE B CE1 1 
ATOM   7247 C  CE2 . PHE B 1 407 ? 16.584  -7.475  -8.781  1 22.041 ? 399  PHE B CE2 1 
ATOM   7248 C  CZ  . PHE B 1 407 ? 15.443  -7.496  -7.98   1 23.275 ? 399  PHE B CZ  1 
ATOM   7249 N  N   . MET B 1 408 ? 21.691  -9.231  -4.196  1 16.841 ? 400  MET B N   1 
ATOM   7250 C  CA  . MET B 1 408 ? 23.065  -9.271  -3.72   1 14.99  ? 400  MET B CA  1 
ATOM   7251 C  C   . MET B 1 408 ? 23.957  -10.004 -4.729  1 14.579 ? 400  MET B C   1 
ATOM   7252 O  O   . MET B 1 408 ? 23.719  -11.176 -5.053  1 12.865 ? 400  MET B O   1 
ATOM   7253 C  CB  . MET B 1 408 ? 23.141  -9.88   -2.308  1 17.11  ? 400  MET B CB  1 
ATOM   7254 C  CG  . MET B 1 408 ? 24.507  -10.043 -1.693  1 18.576 ? 400  MET B CG  1 
ATOM   7255 S  SD  . MET B 1 408 ? 25.526  -8.554  -1.772  1 19.022 ? 400  MET B SD  1 
ATOM   7256 C  CE  . MET B 1 408 ? 25      -7.703  -0.267  1 22.034 ? 400  MET B CE  1 
ATOM   7257 N  N   . GLY B 1 409 ? 25.065  -9.321  -5.125  1 13.877 ? 401  GLY B N   1 
ATOM   7258 C  CA  . GLY B 1 409 ? 26.114  -9.904  -5.961  1 14.06  ? 401  GLY B CA  1 
ATOM   7259 C  C   . GLY B 1 409 ? 25.773  -9.768  -7.455  1 17.493 ? 401  GLY B C   1 
ATOM   7260 O  O   . GLY B 1 409 ? 26.494  -10.325 -8.263  1 15.195 ? 401  GLY B O   1 
ATOM   7261 N  N   . VAL B 1 410 ? 24.686  -9.069  -7.791  1 12.676 ? 402  VAL B N   1 
ATOM   7262 C  CA  . VAL B 1 410 ? 24.321  -8.757  -9.195  1 17.932 ? 402  VAL B CA  1 
ATOM   7263 C  C   . VAL B 1 410 ? 23.905  -7.283  -9.218  1 18.639 ? 402  VAL B C   1 
ATOM   7264 O  O   . VAL B 1 410 ? 23.911  -6.656  -8.155  1 18.203 ? 402  VAL B O   1 
ATOM   7265 C  CB  . VAL B 1 410 ? 23.185  -9.675  -9.711  1 16.73  ? 402  VAL B CB  1 
ATOM   7266 C  CG1 . VAL B 1 410 ? 23.57   -11.146 -9.85   1 12.409 ? 402  VAL B CG1 1 
ATOM   7267 C  CG2 . VAL B 1 410 ? 21.877  -9.514  -8.924  1 21.194 ? 402  VAL B CG2 1 
ATOM   7268 N  N   . GLU B 1 411 ? 23.567  -6.736  -10.391 1 18.24  ? 403  GLU B N   1 
ATOM   7269 C  CA  . GLU B 1 411 ? 23.078  -5.353  -10.5   1 20.017 ? 403  GLU B CA  1 
ATOM   7270 C  C   . GLU B 1 411 ? 21.912  -5.09   -9.554  1 21.824 ? 403  GLU B C   1 
ATOM   7271 O  O   . GLU B 1 411 ? 20.954  -5.896  -9.517  1 18.172 ? 403  GLU B O   1 
ATOM   7272 C  CB  . GLU B 1 411 ? 22.755  -5.022  -11.971 1 17.947 ? 403  GLU B CB  1 
ATOM   7273 C  CG  . GLU B 1 411 ? 22.298  -3.583  -12.13  1 19.363 ? 403  GLU B CG  1 
ATOM   7274 C  CD  . GLU B 1 411 ? 22.138  -3.119  -13.585 1 26.004 ? 403  GLU B CD  1 
ATOM   7275 O  OE1 . GLU B 1 411 ? 22.435  -3.908  -14.522 1 24.264 ? 403  GLU B OE1 1 
ATOM   7276 O  OE2 . GLU B 1 411 ? 21.655  -1.973  -13.752 1 24.495 ? 403  GLU B OE2 1 
ATOM   7277 N  N   . TYR B 1 412 ? 22.04   -3.978  -8.779  1 19.831 ? 404  TYR B N   1 
ATOM   7278 C  CA  . TYR B 1 412 ? 21.064  -3.544  -7.787  1 19.163 ? 404  TYR B CA  1 
ATOM   7279 C  C   . TYR B 1 412 ? 20.825  -2.04   -8.009  1 18.746 ? 404  TYR B C   1 
ATOM   7280 O  O   . TYR B 1 412 ? 21.681  -1.346  -8.596  1 17.033 ? 404  TYR B O   1 
ATOM   7281 C  CB  . TYR B 1 412 ? 21.547  -3.936  -6.367  1 17.909 ? 404  TYR B CB  1 
ATOM   7282 C  CG  . TYR B 1 412 ? 22.516  -2.93   -5.805  1 20.337 ? 404  TYR B CG  1 
ATOM   7283 C  CD1 . TYR B 1 412 ? 23.869  -2.956  -6.136  1 19.016 ? 404  TYR B CD1 1 
ATOM   7284 C  CD2 . TYR B 1 412 ? 22.036  -1.879  -4.992  1 22.982 ? 404  TYR B CD2 1 
ATOM   7285 C  CE1 . TYR B 1 412 ? 24.771  -2.001  -5.666  1 17.639 ? 404  TYR B CE1 1 
ATOM   7286 C  CE2 . TYR B 1 412 ? 22.929  -0.923  -4.514  1 22.121 ? 404  TYR B CE2 1 
ATOM   7287 C  CZ  . TYR B 1 412 ? 24.273  -0.981  -4.864  1 19.061 ? 404  TYR B CZ  1 
ATOM   7288 O  OH  . TYR B 1 412 ? 25.134  -0.039  -4.394  1 21.965 ? 404  TYR B OH  1 
ATOM   7289 N  N   . SER B 1 413 ? 19.653  -1.563  -7.519  1 19.228 ? 405  SER B N   1 
ATOM   7290 C  CA  . SER B 1 413 ? 19.177  -0.194  -7.634  1 18.911 ? 405  SER B CA  1 
ATOM   7291 C  C   . SER B 1 413 ? 18.781  0.408   -6.286  1 21.908 ? 405  SER B C   1 
ATOM   7292 O  O   . SER B 1 413 ? 19.105  1.568   -6.029  1 22.828 ? 405  SER B O   1 
ATOM   7293 C  CB  . SER B 1 413 ? 17.996  -0.143  -8.608  1 20.2   ? 405  SER B CB  1 
ATOM   7294 O  OG  . SER B 1 413 ? 17.625  1.209   -8.803  1 20.943 ? 405  SER B OG  1 
ATOM   7295 N  N   . SER B 1 414 ? 18.003  -0.326  -5.483  1 20.663 ? 406  SER B N   1 
ATOM   7296 C  CA  . SER B 1 414 ? 17.589  0.182   -4.166  1 19.55  ? 406  SER B CA  1 
ATOM   7297 C  C   . SER B 1 414 ? 18.723  0.179   -3.134  1 17.361 ? 406  SER B C   1 
ATOM   7298 O  O   . SER B 1 414 ? 19.463  -0.813  -3.015  1 16.726 ? 406  SER B O   1 
ATOM   7299 C  CB  . SER B 1 414 ? 16.363  -0.559  -3.662  1 17.385 ? 406  SER B CB  1 
ATOM   7300 O  OG  . SER B 1 414 ? 15.211  0.036   -4.29   1 17.492 ? 406  SER B OG  1 
ATOM   7301 N  N   . ALA B 1 415 ? 18.83   1.279   -2.381  1 16.439 ? 407  ALA B N   1 
ATOM   7302 C  CA  . ALA B 1 415 ? 19.617  1.278   -1.149  1 17.044 ? 407  ALA B CA  1 
ATOM   7303 C  C   . ALA B 1 415 ? 18.845  1.997   -0.061  1 18.12  ? 407  ALA B C   1 
ATOM   7304 O  O   . ALA B 1 415 ? 18.21   3.046   -0.296  1 18.033 ? 407  ALA B O   1 
ATOM   7305 C  CB  . ALA B 1 415 ? 20.97   1.95    -1.352  1 17.187 ? 407  ALA B CB  1 
ATOM   7306 N  N   . PHE B 1 416 ? 18.951  1.429   1.141   1 17.329 ? 408  PHE B N   1 
ATOM   7307 C  CA  . PHE B 1 416 ? 18.225  1.961   2.282   1 16.384 ? 408  PHE B CA  1 
ATOM   7308 C  C   . PHE B 1 416 ? 19.331  2.364   3.239   1 17.565 ? 408  PHE B C   1 
ATOM   7309 O  O   . PHE B 1 416 ? 20.141  1.497   3.581   1 16.367 ? 408  PHE B O   1 
ATOM   7310 C  CB  . PHE B 1 416 ? 17.39   0.822   2.909   1 19.753 ? 408  PHE B CB  1 
ATOM   7311 C  CG  . PHE B 1 416 ? 16.387  0.202   1.941   1 17.142 ? 408  PHE B CG  1 
ATOM   7312 C  CD1 . PHE B 1 416 ? 15.179  0.858   1.667   1 16.755 ? 408  PHE B CD1 1 
ATOM   7313 C  CD2 . PHE B 1 416 ? 16.694  -0.998  1.276   1 17.464 ? 408  PHE B CD2 1 
ATOM   7314 C  CE1 . PHE B 1 416 ? 14.282  0.348   0.749   1 21.269 ? 408  PHE B CE1 1 
ATOM   7315 C  CE2 . PHE B 1 416 ? 15.763  -1.548  0.412   1 21.187 ? 408  PHE B CE2 1 
ATOM   7316 C  CZ  . PHE B 1 416 ? 14.567  -0.862  0.157   1 19.497 ? 408  PHE B CZ  1 
ATOM   7317 N  N   . ILE B 1 417 ? 19.424  3.665   3.577   1 16.349 ? 409  ILE B N   1 
ATOM   7318 C  CA  . ILE B 1 417 ? 20.675  4.261   4.074   1 15.049 ? 409  ILE B CA  1 
ATOM   7319 C  C   . ILE B 1 417 ? 20.292  4.969   5.374   1 16.345 ? 409  ILE B C   1 
ATOM   7320 O  O   . ILE B 1 417 ? 19.274  5.676   5.442   1 14.03  ? 409  ILE B O   1 
ATOM   7321 C  CB  . ILE B 1 417 ? 21.241  5.257   3.048   1 15.279 ? 409  ILE B CB  1 
ATOM   7322 C  CG1 . ILE B 1 417 ? 21.332  4.595   1.62    1 14.528 ? 409  ILE B CG1 1 
ATOM   7323 C  CG2 . ILE B 1 417 ? 22.618  5.81    3.525   1 17.475 ? 409  ILE B CG2 1 
ATOM   7324 C  CD1 . ILE B 1 417 ? 21.856  5.505   0.514   1 17.599 ? 409  ILE B CD1 1 
ATOM   7325 N  N   . ASN B 1 418 ? 21.113  4.785   6.402   1 17.169 ? 410  ASN B N   1 
ATOM   7326 C  CA  . ASN B 1 418 ? 20.867  5.557   7.618   1 15.455 ? 410  ASN B CA  1 
ATOM   7327 C  C   . ASN B 1 418 ? 21.482  6.95    7.382   1 15.226 ? 410  ASN B C   1 
ATOM   7328 O  O   . ASN B 1 418 ? 22.591  7.035   6.865   1 16.596 ? 410  ASN B O   1 
ATOM   7329 C  CB  . ASN B 1 418 ? 21.466  4.716   8.729   1 12.861 ? 410  ASN B CB  1 
ATOM   7330 C  CG  . ASN B 1 418 ? 21.088  5.042   10.156  1 11.641 ? 410  ASN B CG  1 
ATOM   7331 O  OD1 . ASN B 1 418 ? 21.694  4.403   11.039  1 12.204 ? 410  ASN B OD1 1 
ATOM   7332 N  ND2 . ASN B 1 418 ? 20.078  5.872   10.421  1 11.932 ? 410  ASN B ND2 1 
ATOM   7333 N  N   . VAL B 1 419 ? 20.761  8.046   7.695   1 16.114 ? 411  VAL B N   1 
ATOM   7334 C  CA  . VAL B 1 419 ? 21.176  9.364   7.233   1 16.7   ? 411  VAL B CA  1 
ATOM   7335 C  C   . VAL B 1 419 ? 21.005  10.431  8.338   1 16.118 ? 411  VAL B C   1 
ATOM   7336 O  O   . VAL B 1 419 ? 20.15   10.351  9.208   1 15.95  ? 411  VAL B O   1 
ATOM   7337 C  CB  . VAL B 1 419 ? 20.519  9.866   5.921   1 17.446 ? 411  VAL B CB  1 
ATOM   7338 C  CG1 . VAL B 1 419 ? 20.878  8.965   4.733   1 14.017 ? 411  VAL B CG1 1 
ATOM   7339 C  CG2 . VAL B 1 419 ? 18.993  9.949   6.042   1 17.596 ? 411  VAL B CG2 1 
ATOM   7340 N  N   . PHE B 1 420 ? 21.868  11.453  8.269   1 15.99  ? 412  PHE B N   1 
ATOM   7341 C  CA  . PHE B 1 420 ? 21.607  12.788  8.805   1 18.994 ? 412  PHE B CA  1 
ATOM   7342 C  C   . PHE B 1 420 ? 20.659  13.472  7.817   1 22.316 ? 412  PHE B C   1 
ATOM   7343 O  O   . PHE B 1 420 ? 21.052  13.728  6.664   1 23.618 ? 412  PHE B O   1 
ATOM   7344 C  CB  . PHE B 1 420 ? 22.884  13.65   8.993   1 18.772 ? 412  PHE B CB  1 
ATOM   7345 C  CG  . PHE B 1 420 ? 23.934  13.245  10.035  1 18.608 ? 412  PHE B CG  1 
ATOM   7346 C  CD1 . PHE B 1 420 ? 24.206  11.891  10.34   1 18.031 ? 412  PHE B CD1 1 
ATOM   7347 C  CD2 . PHE B 1 420 ? 24.657  14.24   10.719  1 19.281 ? 412  PHE B CD2 1 
ATOM   7348 C  CE1 . PHE B 1 420 ? 25.182  11.555  11.294  1 18.973 ? 412  PHE B CE1 1 
ATOM   7349 C  CE2 . PHE B 1 420 ? 25.64   13.905  11.65   1 19.768 ? 412  PHE B CE2 1 
ATOM   7350 C  CZ  . PHE B 1 420 ? 25.935  12.554  11.908  1 17.676 ? 412  PHE B CZ  1 
ATOM   7351 N  N   . VAL B 1 421 ? 19.416  13.717  8.259   1 23.101 ? 413  VAL B N   1 
ATOM   7352 C  CA  . VAL B 1 421 ? 18.375  14.32   7.443   1 25.592 ? 413  VAL B CA  1 
ATOM   7353 C  C   . VAL B 1 421 ? 18.815  15.737  7.031   1 22.316 ? 413  VAL B C   1 
ATOM   7354 O  O   . VAL B 1 421 ? 19.045  16.581  7.911   1 18.291 ? 413  VAL B O   1 
ATOM   7355 C  CB  . VAL B 1 421 ? 16.966  14.269  8.072   1 25.408 ? 413  VAL B CB  1 
ATOM   7356 C  CG1 . VAL B 1 421 ? 15.925  14.947  7.181   1 31.382 ? 413  VAL B CG1 1 
ATOM   7357 C  CG2 . VAL B 1 421 ? 16.542  12.849  8.381   1 20.324 ? 413  VAL B CG2 1 
ATOM   7358 N  N   . PRO B 1 422 ? 18.888  16.051  5.701   1 19.716 ? 414  PRO B N   1 
ATOM   7359 C  CA  . PRO B 1 422 ? 19.211  17.4    5.239   1 26.55  ? 414  PRO B CA  1 
ATOM   7360 C  C   . PRO B 1 422 ? 18.305  18.476  5.851   1 31.611 ? 414  PRO B C   1 
ATOM   7361 O  O   . PRO B 1 422 ? 17.082  18.323  5.947   1 33.284 ? 414  PRO B O   1 
ATOM   7362 C  CB  . PRO B 1 422 ? 19.115  17.334  3.684   1 23.318 ? 414  PRO B CB  1 
ATOM   7363 C  CG  . PRO B 1 422 ? 19.09   15.851  3.384   1 21.817 ? 414  PRO B CG  1 
ATOM   7364 C  CD  . PRO B 1 422 ? 18.719  15.103  4.598   1 21.44  ? 414  PRO B CD  1 
ATOM   7365 N  N   . ASP B 1 423 ? 18.972  19.514  6.371   1 35.366 ? 415  ASP B N   1 
ATOM   7366 C  CA  . ASP B 1 423 ? 18.404  20.731  6.936   1 35.876 ? 415  ASP B CA  1 
ATOM   7367 C  C   . ASP B 1 423 ? 17.735  20.451  8.277   1 37.776 ? 415  ASP B C   1 
ATOM   7368 O  O   . ASP B 1 423 ? 17.229  21.387  8.878   1 37.348 ? 415  ASP B O   1 
ATOM   7369 C  CB  . ASP B 1 423 ? 17.672  21.567  5.898   1 30.338 ? 415  ASP B CB  1 
ATOM   7370 C  CG  . ASP B 1 423 ? 18.405  21.765  4.569   1 40.957 ? 415  ASP B CG  1 
ATOM   7371 O  OD1 . ASP B 1 423 ? 19.558  22.284  4.564   1 40.939 ? 415  ASP B OD1 1 
ATOM   7372 O  OD2 . ASP B 1 423 ? 17.845  21.368  3.53    1 41.898 ? 415  ASP B OD2 1 
ATOM   7373 N  N   . ARG B 1 424 ? 17.79   19.183  8.753   1 32.508 ? 416  ARG B N   1 
ATOM   7374 C  CA  . ARG B 1 424 ? 17.166  18.76   10.005  1 30.152 ? 416  ARG B CA  1 
ATOM   7375 C  C   . ARG B 1 424 ? 18.129  17.88   10.813  1 27.275 ? 416  ARG B C   1 
ATOM   7376 O  O   . ARG B 1 424 ? 17.753  16.837  11.324  1 29.257 ? 416  ARG B O   1 
ATOM   7377 C  CB  . ARG B 1 424 ? 15.823  18.085  9.71    1 32.317 ? 416  ARG B CB  1 
ATOM   7378 C  CG  . ARG B 1 424 ? 15.122  17.778  11.028  1 37.643 ? 416  ARG B CG  1 
ATOM   7379 C  CD  . ARG B 1 424 ? 13.712  18.336  10.994  1 45.646 ? 416  ARG B CD  1 
ATOM   7380 N  NE  . ARG B 1 424 ? 12.917  17.69   9.941   1 41.379 ? 416  ARG B NE  1 
ATOM   7381 C  CZ  . ARG B 1 424 ? 11.664  17.305  10.021  1 39.294 ? 416  ARG B CZ  1 
ATOM   7382 N  NH1 . ARG B 1 424 ? 10.894  17.777  10.989  1 38.448 ? 416  ARG B NH1 1 
ATOM   7383 N  NH2 . ARG B 1 424 ? 11.19   16.51   9.065   1 41.857 ? 416  ARG B NH2 1 
ATOM   7384 N  N   . SER B 1 425 ? 19.38   18.299  10.912  1 25.256 ? 417  SER B N   1 
ATOM   7385 C  CA  . SER B 1 425 ? 20.393  17.485  11.585  1 26.323 ? 417  SER B CA  1 
ATOM   7386 C  C   . SER B 1 425 ? 21.602  18.356  11.906  1 28.954 ? 417  SER B C   1 
ATOM   7387 O  O   . SER B 1 425 ? 21.794  19.385  11.279  1 23.516 ? 417  SER B O   1 
ATOM   7388 C  CB  . SER B 1 425 ? 20.793  16.273  10.75   1 25.364 ? 417  SER B CB  1 
ATOM   7389 O  OG  . SER B 1 425 ? 21.188  16.649  9.425   1 22.231 ? 417  SER B OG  1 
ATOM   7390 N  N   . ASP B 1 426 ? 22.436  17.913  12.862  1 30.803 ? 418  ASP B N   1 
ATOM   7391 C  CA  . ASP B 1 426 ? 23.47   18.785  13.39   1 39.003 ? 418  ASP B CA  1 
ATOM   7392 C  C   . ASP B 1 426 ? 24.528  19.152  12.316  1 48.98  ? 418  ASP B C   1 
ATOM   7393 O  O   . ASP B 1 426 ? 24.661  20.332  11.958  1 66.242 ? 418  ASP B O   1 
ATOM   7394 C  CB  . ASP B 1 426 ? 23.785  18.412  14.832  1 32.402 ? 418  ASP B CB  1 
ATOM   7395 C  CG  . ASP B 1 426 ? 24.908  19.199  15.471  1 30.347 ? 418  ASP B CG  1 
ATOM   7396 O  OD1 . ASP B 1 426 ? 25.694  19.804  14.715  1 25.148 ? 418  ASP B OD1 1 
ATOM   7397 O  OD2 . ASP B 1 426 ? 25.007  19.185  16.709  1 34.651 ? 418  ASP B OD2 1 
ATOM   7398 N  N   . GLY B 1 427 ? 25.246  18.148  11.784  1 35.597 ? 419  GLY B N   1 
ATOM   7399 C  CA  . GLY B 1 427 ? 26.398  18.249  10.897  1 30.408 ? 419  GLY B CA  1 
ATOM   7400 C  C   . GLY B 1 427 ? 27.721  18.056  11.661  1 24.385 ? 419  GLY B C   1 
ATOM   7401 O  O   . GLY B 1 427 ? 28.685  17.435  11.166  1 22.648 ? 419  GLY B O   1 
ATOM   7402 N  N   . ASN B 1 428 ? 27.784  18.647  12.86   1 22.093 ? 420  ASN B N   1 
ATOM   7403 C  CA  . ASN B 1 428 ? 28.989  18.603  13.683  1 24.688 ? 420  ASN B CA  1 
ATOM   7404 C  C   . ASN B 1 428 ? 29.116  17.312  14.492  1 20.393 ? 420  ASN B C   1 
ATOM   7405 O  O   . ASN B 1 428 ? 30.153  17.094  15.132  1 17.734 ? 420  ASN B O   1 
ATOM   7406 C  CB  . ASN B 1 428 ? 29.267  19.91   14.43   1 34.735 ? 420  ASN B CB  1 
ATOM   7407 C  CG  . ASN B 1 428 ? 30.018  20.866  13.511  1 37.655 ? 420  ASN B CG  1 
ATOM   7408 O  OD1 . ASN B 1 428 ? 31.09   20.547  12.959  1 34     ? 420  ASN B OD1 1 
ATOM   7409 N  ND2 . ASN B 1 428 ? 29.438  22.021  13.26   1 34.916 ? 420  ASN B ND2 1 
ATOM   7410 N  N   . LYS B 1 429 ? 28.086  16.475  14.442  1 17.034 ? 421  LYS B N   1 
ATOM   7411 C  CA  . LYS B 1 429 ? 28.098  15.17   15.111  1 21.735 ? 421  LYS B CA  1 
ATOM   7412 C  C   . LYS B 1 429 ? 28.971  14.187  14.344  1 16.192 ? 421  LYS B C   1 
ATOM   7413 O  O   . LYS B 1 429 ? 28.952  14.148  13.09   1 16.088 ? 421  LYS B O   1 
ATOM   7414 C  CB  . LYS B 1 429 ? 26.693  14.588  15.29   1 23.105 ? 421  LYS B CB  1 
ATOM   7415 C  CG  . LYS B 1 429 ? 25.75   15.344  16.227  1 28.996 ? 421  LYS B CG  1 
ATOM   7416 C  CD  . LYS B 1 429 ? 26.04   15.373  17.726  1 33.194 ? 421  LYS B CD  1 
ATOM   7417 C  CE  . LYS B 1 429 ? 25.946  14.129  18.536  1 29.446 ? 421  LYS B CE  1 
ATOM   7418 N  NZ  . LYS B 1 429 ? 25.737  14.675  19.891  1 38.502 ? 421  LYS B NZ  1 
ATOM   7419 N  N   . ASN B 1 430 ? 29.724  13.38   15.098  1 16.331 ? 422  ASN B N   1 
ATOM   7420 C  CA  . ASN B 1 430 ? 30.352  12.191  14.496  1 16.674 ? 422  ASN B CA  1 
ATOM   7421 C  C   . ASN B 1 430 ? 29.332  11.407  13.672  1 17.623 ? 422  ASN B C   1 
ATOM   7422 O  O   . ASN B 1 430 ? 28.14   11.393  14.022  1 14.723 ? 422  ASN B O   1 
ATOM   7423 C  CB  . ASN B 1 430 ? 31.062  11.382  15.577  1 19.631 ? 422  ASN B CB  1 
ATOM   7424 C  CG  . ASN B 1 430 ? 31.509  10.014  15.118  1 15.175 ? 422  ASN B CG  1 
ATOM   7425 O  OD1 . ASN B 1 430 ? 30.743  9.044   15.211  1 13.329 ? 422  ASN B OD1 1 
ATOM   7426 N  ND2 . ASN B 1 430 ? 32.746  9.928   14.677  1 18.712 ? 422  ASN B ND2 1 
ATOM   7427 N  N   . VAL B 1 431 ? 29.783  10.727  12.591  1 16.752 ? 423  VAL B N   1 
ATOM   7428 C  CA  . VAL B 1 431 ? 28.844  10.136  11.631  1 16.636 ? 423  VAL B CA  1 
ATOM   7429 C  C   . VAL B 1 431 ? 27.958  9.079   12.294  1 15.173 ? 423  VAL B C   1 
ATOM   7430 O  O   . VAL B 1 431 ? 26.81   8.908   11.894  1 13.868 ? 423  VAL B O   1 
ATOM   7431 C  CB  . VAL B 1 431 ? 29.585  9.595   10.386  1 14.549 ? 423  VAL B CB  1 
ATOM   7432 C  CG1 . VAL B 1 431 ? 30.394  8.316   10.68   1 13.779 ? 423  VAL B CG1 1 
ATOM   7433 C  CG2 . VAL B 1 431 ? 28.663  9.364   9.196   1 13.863 ? 423  VAL B CG2 1 
ATOM   7434 N  N   . PHE B 1 432 ? 28.46   8.433   13.391  1 14.53  ? 424  PHE B N   1 
ATOM   7435 C  CA  . PHE B 1 432 ? 27.667  7.397   14.072  1 15.216 ? 424  PHE B CA  1 
ATOM   7436 C  C   . PHE B 1 432 ? 26.663  7.995   15.058  1 14.75  ? 424  PHE B C   1 
ATOM   7437 O  O   . PHE B 1 432 ? 25.792  7.256   15.541  1 16.174 ? 424  PHE B O   1 
ATOM   7438 C  CB  . PHE B 1 432 ? 28.535  6.343   14.775  1 13.782 ? 424  PHE B CB  1 
ATOM   7439 C  CG  . PHE B 1 432 ? 29.359  5.596   13.741  1 14.95  ? 424  PHE B CG  1 
ATOM   7440 C  CD1 . PHE B 1 432 ? 28.753  4.68    12.867  1 16.99  ? 424  PHE B CD1 1 
ATOM   7441 C  CD2 . PHE B 1 432 ? 30.717  5.889   13.568  1 16.916 ? 424  PHE B CD2 1 
ATOM   7442 C  CE1 . PHE B 1 432 ? 29.532  4.007   11.927  1 17.531 ? 424  PHE B CE1 1 
ATOM   7443 C  CE2 . PHE B 1 432 ? 31.481  5.253   12.615  1 18.063 ? 424  PHE B CE2 1 
ATOM   7444 C  CZ  . PHE B 1 432 ? 30.889  4.311   11.808  1 21.078 ? 424  PHE B CZ  1 
ATOM   7445 N  N   . GLN B 1 433 ? 26.735  9.312   15.296  1 14.077 ? 425  GLN B N   1 
ATOM   7446 C  CA  . GLN B 1 433 ? 26.064  9.922   16.447  1 16.059 ? 425  GLN B CA  1 
ATOM   7447 C  C   . GLN B 1 433 ? 24.917  10.884  16.122  1 17.431 ? 425  GLN B C   1 
ATOM   7448 O  O   . GLN B 1 433 ? 24.303  11.373  17.066  1 15.704 ? 425  GLN B O   1 
ATOM   7449 C  CB  . GLN B 1 433 ? 27.086  10.568  17.386  1 15.766 ? 425  GLN B CB  1 
ATOM   7450 C  CG  . GLN B 1 433 ? 28.232  9.623   17.79   1 16.639 ? 425  GLN B CG  1 
ATOM   7451 C  CD  . GLN B 1 433 ? 29.07   10.177  18.906  1 22.208 ? 425  GLN B CD  1 
ATOM   7452 O  OE1 . GLN B 1 433 ? 28.902  11.346  19.267  1 22.281 ? 425  GLN B OE1 1 
ATOM   7453 N  NE2 . GLN B 1 433 ? 29.896  9.323   19.522  1 21.955 ? 425  GLN B NE2 1 
ATOM   7454 N  N   . GLY B 1 434 ? 24.593  11.144  14.837  1 15.477 ? 426  GLY B N   1 
ATOM   7455 C  CA  . GLY B 1 434 ? 23.542  12.098  14.525  1 17.468 ? 426  GLY B CA  1 
ATOM   7456 C  C   . GLY B 1 434 ? 22.611  11.527  13.451  1 18.811 ? 426  GLY B C   1 
ATOM   7457 O  O   . GLY B 1 434 ? 21.961  12.261  12.692  1 16.434 ? 426  GLY B O   1 
ATOM   7458 N  N   . LEU B 1 435 ? 22.603  10.181  13.335  1 20.073 ? 427  LEU B N   1 
ATOM   7459 C  CA  . LEU B 1 435 ? 21.807  9.492   12.331  1 17.641 ? 427  LEU B CA  1 
ATOM   7460 C  C   . LEU B 1 435 ? 20.339  9.527   12.752  1 19.806 ? 427  LEU B C   1 
ATOM   7461 O  O   . LEU B 1 435 ? 19.882  8.775   13.639  1 18.034 ? 427  LEU B O   1 
ATOM   7462 C  CB  . LEU B 1 435 ? 22.327  8.093   11.956  1 20.101 ? 427  LEU B CB  1 
ATOM   7463 C  CG  . LEU B 1 435 ? 23.763  8.01    11.427  1 19.247 ? 427  LEU B CG  1 
ATOM   7464 C  CD1 . LEU B 1 435 ? 24.372  6.606   11.756  1 17.187 ? 427  LEU B CD1 1 
ATOM   7465 C  CD2 . LEU B 1 435 ? 23.93   8.328   9.889   1 14.163 ? 427  LEU B CD2 1 
ATOM   7466 N  N   . ASN B 1 436 ? 19.603  10.467  12.133  1 18.822 ? 428  ASN B N   1 
ATOM   7467 C  CA  . ASN B 1 436 ? 18.241  10.703  12.61   1 21.294 ? 428  ASN B CA  1 
ATOM   7468 C  C   . ASN B 1 436 ? 17.19   10.474  11.511  1 21.446 ? 428  ASN B C   1 
ATOM   7469 O  O   . ASN B 1 436 ? 16.071  10.949  11.63   1 22.535 ? 428  ASN B O   1 
ATOM   7470 C  CB  . ASN B 1 436 ? 18.136  12.098  13.253  1 25.118 ? 428  ASN B CB  1 
ATOM   7471 C  CG  . ASN B 1 436 ? 18.277  13.265  12.289  1 29.439 ? 428  ASN B CG  1 
ATOM   7472 O  OD1 . ASN B 1 436 ? 18.778  13.155  11.151  1 25.637 ? 428  ASN B OD1 1 
ATOM   7473 N  ND2 . ASN B 1 436 ? 17.813  14.423  12.746  1 31.419 ? 428  ASN B ND2 1 
ATOM   7474 N  N   . GLY B 1 437 ? 17.587  9.836   10.418  1 17.98  ? 429  GLY B N   1 
ATOM   7475 C  CA  . GLY B 1 437 ? 16.652  9.575   9.325   1 19.534 ? 429  GLY B CA  1 
ATOM   7476 C  C   . GLY B 1 437 ? 17.018  8.33    8.524   1 20.128 ? 429  GLY B C   1 
ATOM   7477 O  O   . GLY B 1 437 ? 18.095  7.76    8.721   1 16.447 ? 429  GLY B O   1 
ATOM   7478 N  N   . LEU B 1 438 ? 16.098  7.92    7.623   1 15.968 ? 430  LEU B N   1 
ATOM   7479 C  CA  . LEU B 1 438 ? 16.451  6.941   6.619   1 16.236 ? 430  LEU B CA  1 
ATOM   7480 C  C   . LEU B 1 438 ? 16.273  7.552   5.243   1 17.077 ? 430  LEU B C   1 
ATOM   7481 O  O   . LEU B 1 438 ? 15.382  8.37    5.082   1 22.525 ? 430  LEU B O   1 
ATOM   7482 C  CB  . LEU B 1 438 ? 15.601  5.671   6.698   1 17.062 ? 430  LEU B CB  1 
ATOM   7483 C  CG  . LEU B 1 438 ? 15.448  5.062   8.105   1 15.314 ? 430  LEU B CG  1 
ATOM   7484 C  CD1 . LEU B 1 438 ? 14.411  3.938   8.101   1 16.613 ? 430  LEU B CD1 1 
ATOM   7485 C  CD2 . LEU B 1 438 ? 16.825  4.492   8.376   1 19.463 ? 430  LEU B CD2 1 
ATOM   7486 N  N   . ALA B 1 439 ? 17.003  7.005   4.276   1 19.54  ? 431  ALA B N   1 
ATOM   7487 C  CA  . ALA B 1 439 ? 16.764  7.356   2.871   1 18.206 ? 431  ALA B CA  1 
ATOM   7488 C  C   . ALA B 1 439 ? 16.568  6.104   2.043   1 19.424 ? 431  ALA B C   1 
ATOM   7489 O  O   . ALA B 1 439 ? 17.303  5.125   2.249   1 19.191 ? 431  ALA B O   1 
ATOM   7490 C  CB  . ALA B 1 439 ? 17.975  8.129   2.388   1 22.797 ? 431  ALA B CB  1 
ATOM   7491 N  N   . HIS B 1 440 ? 15.59   6.134   1.114   1 18.706 ? 432  HIS B N   1 
ATOM   7492 C  CA  . HIS B 1 440 ? 15.471  5.115   0.082   1 20.141 ? 432  HIS B CA  1 
ATOM   7493 C  C   . HIS B 1 440 ? 15.932  5.727   -1.237  1 19.791 ? 432  HIS B C   1 
ATOM   7494 O  O   . HIS B 1 440 ? 15.192  6.501   -1.84   1 22.696 ? 432  HIS B O   1 
ATOM   7495 C  CB  . HIS B 1 440 ? 14.039  4.572   -0.052  1 18.704 ? 432  HIS B CB  1 
ATOM   7496 C  CG  . HIS B 1 440 ? 13.866  3.427   -1.022  1 18.723 ? 432  HIS B CG  1 
ATOM   7497 N  ND1 . HIS B 1 440 ? 12.617  2.909   -1.261  1 19.89  ? 432  HIS B ND1 1 
ATOM   7498 C  CD2 . HIS B 1 440 ? 14.737  2.632   -1.684  1 18.068 ? 432  HIS B CD2 1 
ATOM   7499 C  CE1 . HIS B 1 440 ? 12.722  1.859   -2.07   1 21.435 ? 432  HIS B CE1 1 
ATOM   7500 N  NE2 . HIS B 1 440 ? 13.994  1.694   -2.368  1 23.526 ? 432  HIS B NE2 1 
ATOM   7501 N  N   . TYR B 1 441 ? 17.126  5.325   -1.682  1 16.557 ? 433  TYR B N   1 
ATOM   7502 C  CA  . TYR B 1 441 ? 17.701  5.793   -2.93   1 17.651 ? 433  TYR B CA  1 
ATOM   7503 C  C   . TYR B 1 441 ? 17.451  4.703   -3.952  1 19.131 ? 433  TYR B C   1 
ATOM   7504 O  O   . TYR B 1 441 ? 17.629  3.52    -3.641  1 18.55  ? 433  TYR B O   1 
ATOM   7505 C  CB  . TYR B 1 441 ? 19.218  6.041   -2.754  1 19.022 ? 433  TYR B CB  1 
ATOM   7506 C  CG  . TYR B 1 441 ? 19.975  6.209   -4.077  1 21.392 ? 433  TYR B CG  1 
ATOM   7507 C  CD1 . TYR B 1 441 ? 19.84   7.376   -4.854  1 17.068 ? 433  TYR B CD1 1 
ATOM   7508 C  CD2 . TYR B 1 441 ? 20.855  5.214   -4.524  1 21.206 ? 433  TYR B CD2 1 
ATOM   7509 C  CE1 . TYR B 1 441 ? 20.521  7.524   -6.05   1 19.203 ? 433  TYR B CE1 1 
ATOM   7510 C  CE2 . TYR B 1 441 ? 21.564  5.374   -5.724  1 24.313 ? 433  TYR B CE2 1 
ATOM   7511 C  CZ  . TYR B 1 441 ? 21.375  6.52    -6.497  1 20.099 ? 433  TYR B CZ  1 
ATOM   7512 O  OH  . TYR B 1 441 ? 22.106  6.72    -7.636  1 22.085 ? 433  TYR B OH  1 
ATOM   7513 N  N   . LYS B 1 442 ? 17.061  5.121   -5.187  1 19.79  ? 434  LYS B N   1 
ATOM   7514 C  CA  . LYS B 1 442 ? 16.922  4.185   -6.277  1 21.031 ? 434  LYS B CA  1 
ATOM   7515 C  C   . LYS B 1 442 ? 17.753  4.717   -7.433  1 25.254 ? 434  LYS B C   1 
ATOM   7516 O  O   . LYS B 1 442 ? 17.363  5.734   -8.022  1 20.707 ? 434  LYS B O   1 
ATOM   7517 C  CB  . LYS B 1 442 ? 15.437  4.117   -6.674  1 25.179 ? 434  LYS B CB  1 
ATOM   7518 C  CG  . LYS B 1 442 ? 14.539  3.199   -5.83   1 28.304 ? 434  LYS B CG  1 
ATOM   7519 C  CD  . LYS B 1 442 ? 13.083  3.462   -6.184  1 28.127 ? 434  LYS B CD  1 
ATOM   7520 C  CE  . LYS B 1 442 ? 12.158  2.568   -5.473  1 33.232 ? 434  LYS B CE  1 
ATOM   7521 N  NZ  . LYS B 1 442 ? 10.794  2.657   -6.034  1 30.611 ? 434  LYS B NZ  1 
ATOM   7522 N  N   . ARG B 1 443 ? 18.862  4.013   -7.726  1 22.202 ? 435  ARG B N   1 
ATOM   7523 C  CA  . ARG B 1 443 ? 19.805  4.384   -8.77   1 18.717 ? 435  ARG B CA  1 
ATOM   7524 C  C   . ARG B 1 443 ? 19.102  4.47    -10.137 1 19.436 ? 435  ARG B C   1 
ATOM   7525 O  O   . ARG B 1 443 ? 19.314  5.443   -10.864 1 21.665 ? 435  ARG B O   1 
ATOM   7526 C  CB  . ARG B 1 443 ? 20.895  3.325   -8.937  1 18.101 ? 435  ARG B CB  1 
ATOM   7527 C  CG  . ARG B 1 443 ? 22.003  3.687   -9.934  1 20.217 ? 435  ARG B CG  1 
ATOM   7528 C  CD  . ARG B 1 443 ? 23.15   2.647   -9.937  1 18.262 ? 435  ARG B CD  1 
ATOM   7529 N  NE  . ARG B 1 443 ? 22.659  1.28    -10.161 1 21.173 ? 435  ARG B NE  1 
ATOM   7530 C  CZ  . ARG B 1 443 ? 22.242  0.695   -11.293 1 22.597 ? 435  ARG B CZ  1 
ATOM   7531 N  NH1 . ARG B 1 443 ? 22.192  1.376   -12.454 1 23.365 ? 435  ARG B NH1 1 
ATOM   7532 N  NH2 . ARG B 1 443 ? 21.923  -0.582  -11.245 1 20.277 ? 435  ARG B NH2 1 
ATOM   7533 N  N   . LYS B 1 444 ? 18.208  3.527   -10.433 1 20.209 ? 436  LYS B N   1 
ATOM   7534 C  CA  . LYS B 1 444 ? 17.633  3.481   -11.791 1 25.133 ? 436  LYS B CA  1 
ATOM   7535 C  C   . LYS B 1 444 ? 16.714  4.682   -12.074 1 33.212 ? 436  LYS B C   1 
ATOM   7536 O  O   . LYS B 1 444 ? 16.734  5.231   -13.191 1 32.031 ? 436  LYS B O   1 
ATOM   7537 C  CB  . LYS B 1 444 ? 16.998  2.121   -12.057 1 25.287 ? 436  LYS B CB  1 
ATOM   7538 C  CG  . LYS B 1 444 ? 17.985  1.058   -12.415 1 30.596 ? 436  LYS B CG  1 
ATOM   7539 C  CD  . LYS B 1 444 ? 17.32   -0.308  -12.324 1 27.84  ? 436  LYS B CD  1 
ATOM   7540 C  CE  . LYS B 1 444 ? 18.47   -1.266  -12.463 1 35.528 ? 436  LYS B CE  1 
ATOM   7541 N  NZ  . LYS B 1 444 ? 18.175  -2.539  -13.113 1 36.411 ? 436  LYS B NZ  1 
ATOM   7542 N  N   . GLU B 1 445 ? 15.895  5.065   -11.08  1 29.089 ? 437  GLU B N   1 
ATOM   7543 C  CA  . GLU B 1 445 ? 15.004  6.224   -11.119 1 29.567 ? 437  GLU B CA  1 
ATOM   7544 C  C   . GLU B 1 445 ? 15.774  7.517   -10.811 1 28.387 ? 437  GLU B C   1 
ATOM   7545 O  O   . GLU B 1 445 ? 15.353  8.606   -11.187 1 27.918 ? 437  GLU B O   1 
ATOM   7546 C  CB  . GLU B 1 445 ? 13.801  6.113   -10.184 1 32.681 ? 437  GLU B CB  1 
ATOM   7547 C  CG  . GLU B 1 445 ? 12.838  4.967   -10.484 1 31.681 ? 437  GLU B CG  1 
ATOM   7548 C  CD  . GLU B 1 445 ? 13.187  3.531   -10.151 1 34.543 ? 437  GLU B CD  1 
ATOM   7549 O  OE1 . GLU B 1 445 ? 14.324  3.256   -9.689  1 31.569 ? 437  GLU B OE1 1 
ATOM   7550 O  OE2 . GLU B 1 445 ? 12.29   2.67    -10.344 1 29.074 ? 437  GLU B OE2 1 
ATOM   7551 N  N   . GLY B 1 446 ? 16.907  7.402   -10.116 1 26.622 ? 438  GLY B N   1 
ATOM   7552 C  CA  . GLY B 1 446 ? 17.632  8.555   -9.626  1 29.327 ? 438  GLY B CA  1 
ATOM   7553 C  C   . GLY B 1 446 ? 16.863  9.321   -8.541  1 33.152 ? 438  GLY B C   1 
ATOM   7554 O  O   . GLY B 1 446 ? 17.16   10.502  -8.337  1 35.861 ? 438  GLY B O   1 
ATOM   7555 N  N   . THR B 1 447 ? 15.938  8.635   -7.834  1 25.987 ? 439  THR B N   1 
ATOM   7556 C  CA  . THR B 1 447 ? 15.122  9.275   -6.797  1 21.488 ? 439  THR B CA  1 
ATOM   7557 C  C   . THR B 1 447 ? 15.67   8.948   -5.397  1 22.125 ? 439  THR B C   1 
ATOM   7558 O  O   . THR B 1 447 ? 16.282  7.884   -5.21   1 19.435 ? 439  THR B O   1 
ATOM   7559 C  CB  . THR B 1 447 ? 13.636  8.935   -6.889  1 27.251 ? 439  THR B CB  1 
ATOM   7560 O  OG1 . THR B 1 447 ? 13.533  7.537   -6.675  1 25.986 ? 439  THR B OG1 1 
ATOM   7561 C  CG2 . THR B 1 447 ? 12.962  9.222   -8.232  1 32.501 ? 439  THR B CG2 1 
ATOM   7562 N  N   . THR B 1 448 ? 15.483  9.887   -4.46   1 18.146 ? 440  THR B N   1 
ATOM   7563 C  CA  . THR B 1 448 ? 15.682  9.615   -3.028  1 22.845 ? 440  THR B CA  1 
ATOM   7564 C  C   . THR B 1 448 ? 14.405  9.979   -2.281  1 27.587 ? 440  THR B C   1 
ATOM   7565 O  O   . THR B 1 448 ? 13.801  11.037  -2.55   1 24.481 ? 440  THR B O   1 
ATOM   7566 C  CB  . THR B 1 448 ? 16.905  10.37   -2.5    1 22.505 ? 440  THR B CB  1 
ATOM   7567 O  OG1 . THR B 1 448 ? 17.956  10.055  -3.404  1 20.788 ? 440  THR B OG1 1 
ATOM   7568 C  CG2 . THR B 1 448 ? 17.349  9.935   -1.112  1 24.69  ? 440  THR B CG2 1 
ATOM   7569 N  N   . GLU B 1 449 ? 13.965  9.081   -1.373  1 24.028 ? 441  GLU B N   1 
ATOM   7570 C  CA  . GLU B 1 449 ? 12.893  9.453   -0.46   1 19.197 ? 441  GLU B CA  1 
ATOM   7571 C  C   . GLU B 1 449 ? 13.425  9.33    0.98    1 20.899 ? 441  GLU B C   1 
ATOM   7572 O  O   . GLU B 1 449 ? 14.426  8.679   1.208   1 19.786 ? 441  GLU B O   1 
ATOM   7573 C  CB  . GLU B 1 449 ? 11.7    8.525   -0.67   1 18.35  ? 441  GLU B CB  1 
ATOM   7574 C  CG  . GLU B 1 449 ? 11.326  8.442   -2.157  1 23.739 ? 441  GLU B CG  1 
ATOM   7575 C  CD  . GLU B 1 449 ? 10.492  7.218   -2.422  1 24.101 ? 441  GLU B CD  1 
ATOM   7576 O  OE1 . GLU B 1 449 ? 9.353   7.414   -2.06   1 27.575 ? 441  GLU B OE1 1 
ATOM   7577 O  OE2 . GLU B 1 449 ? 10.907  6.137   -2.881  1 29.531 ? 441  GLU B OE2 1 
ATOM   7578 N  N   . TRP B 1 450 ? 12.756  9.977   1.925   1 20.596 ? 442  TRP B N   1 
ATOM   7579 C  CA  . TRP B 1 450 ? 13.364  10.271  3.226   1 20.392 ? 442  TRP B CA  1 
ATOM   7580 C  C   . TRP B 1 450 ? 12.325  10.005  4.3     1 20.807 ? 442  TRP B C   1 
ATOM   7581 O  O   . TRP B 1 450 ? 11.163  10.398  4.166   1 19.65  ? 442  TRP B O   1 
ATOM   7582 C  CB  . TRP B 1 450 ? 13.795  11.76   3.308   1 20.572 ? 442  TRP B CB  1 
ATOM   7583 C  CG  . TRP B 1 450 ? 14.745  12.207  2.218   1 22.042 ? 442  TRP B CG  1 
ATOM   7584 C  CD1 . TRP B 1 450 ? 14.42   12.578  0.933   1 24.037 ? 442  TRP B CD1 1 
ATOM   7585 C  CD2 . TRP B 1 450 ? 16.191  12.222  2.283   1 22.785 ? 442  TRP B CD2 1 
ATOM   7586 N  NE1 . TRP B 1 450 ? 15.55   12.869  0.215   1 24.682 ? 442  TRP B NE1 1 
ATOM   7587 C  CE2 . TRP B 1 450 ? 16.654  12.659  1.016   1 22.079 ? 442  TRP B CE2 1 
ATOM   7588 C  CE3 . TRP B 1 450 ? 17.138  11.987  3.302   1 20.597 ? 442  TRP B CE3 1 
ATOM   7589 C  CZ2 . TRP B 1 450 ? 18.008  12.839  0.749   1 19.304 ? 442  TRP B CZ2 1 
ATOM   7590 C  CZ3 . TRP B 1 450 ? 18.49   12.165  3.026   1 18.286 ? 442  TRP B CZ3 1 
ATOM   7591 C  CH2 . TRP B 1 450 ? 18.921  12.571  1.751   1 23.426 ? 442  TRP B CH2 1 
ATOM   7592 N  N   . TYR B 1 451 ? 12.807  9.444   5.416   1 19.37  ? 443  TYR B N   1 
ATOM   7593 C  CA  . TYR B 1 451 ? 12.021  9.176   6.61    1 20.776 ? 443  TYR B CA  1 
ATOM   7594 C  C   . TYR B 1 451 ? 12.742  9.896   7.748   1 18.069 ? 443  TYR B C   1 
ATOM   7595 O  O   . TYR B 1 451 ? 13.968  9.731   7.931   1 17.861 ? 443  TYR B O   1 
ATOM   7596 C  CB  . TYR B 1 451 ? 11.832  7.662   6.861   1 18.421 ? 443  TYR B CB  1 
ATOM   7597 C  CG  . TYR B 1 451 ? 11.116  7.426   8.182   1 19.572 ? 443  TYR B CG  1 
ATOM   7598 C  CD1 . TYR B 1 451 ? 9.714   7.537   8.295   1 17.473 ? 443  TYR B CD1 1 
ATOM   7599 C  CD2 . TYR B 1 451 ? 11.857  7.17    9.343   1 18.603 ? 443  TYR B CD2 1 
ATOM   7600 C  CE1 . TYR B 1 451 ? 9.08    7.366   9.525   1 17.182 ? 443  TYR B CE1 1 
ATOM   7601 C  CE2 . TYR B 1 451 ? 11.224  7.027   10.575  1 16.492 ? 443  TYR B CE2 1 
ATOM   7602 C  CZ  . TYR B 1 451 ? 9.844   7.096   10.659  1 17.492 ? 443  TYR B CZ  1 
ATOM   7603 O  OH  . TYR B 1 451 ? 9.226   7.009   11.886  1 17.288 ? 443  TYR B OH  1 
ATOM   7604 N  N   . TYR B 1 452 ? 11.99   10.732  8.484   1 21.835 ? 444  TYR B N   1 
ATOM   7605 C  CA  . TYR B 1 452 ? 12.566  11.449  9.614   1 20.274 ? 444  TYR B CA  1 
ATOM   7606 C  C   . TYR B 1 452 ? 12.152  10.704  10.885  1 21.7   ? 444  TYR B C   1 
ATOM   7607 O  O   . TYR B 1 452 ? 10.952  10.424  11.044  1 21.53  ? 444  TYR B O   1 
ATOM   7608 C  CB  . TYR B 1 452 ? 12.004  12.88   9.667   1 24.537 ? 444  TYR B CB  1 
ATOM   7609 C  CG  . TYR B 1 452 ? 12.382  13.697  10.895  1 26.719 ? 444  TYR B CG  1 
ATOM   7610 C  CD1 . TYR B 1 452 ? 13.725  13.904  11.228  1 29.753 ? 444  TYR B CD1 1 
ATOM   7611 C  CD2 . TYR B 1 452 ? 11.404  14.309  11.69   1 31.738 ? 444  TYR B CD2 1 
ATOM   7612 C  CE1 . TYR B 1 452 ? 14.078  14.667  12.338  1 29.241 ? 444  TYR B CE1 1 
ATOM   7613 C  CE2 . TYR B 1 452 ? 11.747  15.06   12.808  1 25.168 ? 444  TYR B CE2 1 
ATOM   7614 C  CZ  . TYR B 1 452 ? 13.093  15.275  13.1    1 27.052 ? 444  TYR B CZ  1 
ATOM   7615 O  OH  . TYR B 1 452 ? 13.48   15.956  14.223  1 33.024 ? 444  TYR B OH  1 
ATOM   7616 N  N   . ALA B 1 453 ? 13.154  10.394  11.746  1 21.23  ? 445  ALA B N   1 
ATOM   7617 C  CA  . ALA B 1 453 ? 12.956  9.599   12.964  1 20.715 ? 445  ALA B CA  1 
ATOM   7618 C  C   . ALA B 1 453 ? 12.042  10.356  13.941  1 23.54  ? 445  ALA B C   1 
ATOM   7619 O  O   . ALA B 1 453 ? 11.29   9.732   14.691  1 24.929 ? 445  ALA B O   1 
ATOM   7620 C  CB  . ALA B 1 453 ? 14.287  9.308   13.638  1 19.757 ? 445  ALA B CB  1 
ATOM   7621 N  N   . GLY B 1 454 ? 12.077  11.695  13.895  1 26.387 ? 446  GLY B N   1 
ATOM   7622 C  CA  . GLY B 1 454 ? 11.321  12.477  14.861  1 22.47  ? 446  GLY B CA  1 
ATOM   7623 C  C   . GLY B 1 454 ? 12.206  13.368  15.697  1 25.804 ? 446  GLY B C   1 
ATOM   7624 O  O   . GLY B 1 454 ? 13.443  13.205  15.741  1 24.398 ? 446  GLY B O   1 
ATOM   7625 N  N   . ASP B 1 455 ? 11.557  14.373  16.314  1 24.177 ? 447  ASP B N   1 
ATOM   7626 C  CA  . ASP B 1 455 ? 12.268  15.182  17.293  1 30.623 ? 447  ASP B CA  1 
ATOM   7627 C  C   . ASP B 1 455 ? 12.65   14.294  18.478  1 28.806 ? 447  ASP B C   1 
ATOM   7628 O  O   . ASP B 1 455 ? 11.82   13.481  18.919  1 36.623 ? 447  ASP B O   1 
ATOM   7629 C  CB  . ASP B 1 455 ? 11.429  16.372  17.738  1 30.692 ? 447  ASP B CB  1 
ATOM   7630 C  CG  . ASP B 1 455 ? 11.181  17.454  16.686  1 37.704 ? 447  ASP B CG  1 
ATOM   7631 O  OD1 . ASP B 1 455 ? 11.477  17.24   15.458  1 29.633 ? 447  ASP B OD1 1 
ATOM   7632 O  OD2 . ASP B 1 455 ? 10.683  18.532  17.091  1 37.692 ? 447  ASP B OD2 1 
ATOM   7633 N  N   . ASN B 1 456 ? 13.885  14.49   18.958  1 27.327 ? 448  ASN B N   1 
ATOM   7634 C  CA  . ASN B 1 456 ? 14.487  13.808  20.111  1 37.344 ? 448  ASN B CA  1 
ATOM   7635 C  C   . ASN B 1 456 ? 14.537  12.3    19.891  1 38.87  ? 448  ASN B C   1 
ATOM   7636 O  O   . ASN B 1 456 ? 14.257  11.505  20.81   1 35.122 ? 448  ASN B O   1 
ATOM   7637 C  CB  . ASN B 1 456 ? 13.842  14.113  21.464  1 40.395 ? 448  ASN B CB  1 
ATOM   7638 C  CG  . ASN B 1 456 ? 13.682  15.576  21.735  1 39.487 ? 448  ASN B CG  1 
ATOM   7639 O  OD1 . ASN B 1 456 ? 14.6    16.349  21.462  1 43.066 ? 448  ASN B OD1 1 
ATOM   7640 N  ND2 . ASN B 1 456 ? 12.484  15.964  22.152  1 53.429 ? 448  ASN B ND2 1 
ATOM   7641 N  N   . CYS B 1 457 ? 14.874  11.943  18.638  1 42.847 ? 449  CYS B N   1 
ATOM   7642 C  CA  . CYS B 1 457 ? 15.01   10.556  18.217  1 33.611 ? 449  CYS B CA  1 
ATOM   7643 C  C   . CYS B 1 457 ? 16.274  10.4    17.375  1 28.734 ? 449  CYS B C   1 
ATOM   7644 O  O   . CYS B 1 457 ? 16.676  11.296  16.597  1 24.369 ? 449  CYS B O   1 
ATOM   7645 C  CB  . CYS B 1 457 ? 13.822  10.103  17.373  1 36.945 ? 449  CYS B CB  1 
ATOM   7646 S  SG  . CYS B 1 457 ? 12.201  10.067  18.208  1 35.811 ? 449  CYS B SG  1 
ATOM   7647 N  N   . LEU B 1 458 ? 16.834  9.195   17.47   1 22.299 ? 450  LEU B N   1 
ATOM   7648 C  CA  . LEU B 1 458 ? 17.78   8.685   16.478  1 23.566 ? 450  LEU B CA  1 
ATOM   7649 C  C   . LEU B 1 458 ? 17.234  7.379   15.916  1 19.573 ? 450  LEU B C   1 
ATOM   7650 O  O   . LEU B 1 458 ? 16.366  6.767   16.498  1 21.599 ? 450  LEU B O   1 
ATOM   7651 C  CB  . LEU B 1 458 ? 19.178  8.49    17.088  1 22.538 ? 450  LEU B CB  1 
ATOM   7652 C  CG  . LEU B 1 458 ? 19.849  9.746   17.644  1 25.314 ? 450  LEU B CG  1 
ATOM   7653 C  CD1 . LEU B 1 458 ? 20.887  9.359   18.665  1 27.391 ? 450  LEU B CD1 1 
ATOM   7654 C  CD2 . LEU B 1 458 ? 20.438  10.67   16.594  1 22.056 ? 450  LEU B CD2 1 
ATOM   7655 N  N   . ILE B 1 459 ? 17.719  6.996   14.727  1 20.601 ? 451  ILE B N   1 
ATOM   7656 C  CA  . ILE B 1 459 ? 17.233  5.795   14.076  1 16.779 ? 451  ILE B CA  1 
ATOM   7657 C  C   . ILE B 1 459 ? 18.477  5.018   13.633  1 13.692 ? 451  ILE B C   1 
ATOM   7658 O  O   . ILE B 1 459 ? 19.498  5.625   13.292  1 17.775 ? 451  ILE B O   1 
ATOM   7659 C  CB  . ILE B 1 459 ? 16.24   6.078   12.927  1 19.392 ? 451  ILE B CB  1 
ATOM   7660 C  CG1 . ILE B 1 459 ? 15.455  4.842   12.547  1 17.73  ? 451  ILE B CG1 1 
ATOM   7661 C  CG2 . ILE B 1 459 ? 16.908  6.742   11.721  1 16.95  ? 451  ILE B CG2 1 
ATOM   7662 C  CD1 . ILE B 1 459 ? 14.137  5.105   11.825  1 17.42  ? 451  ILE B CD1 1 
ATOM   7663 N  N   . GLN B 1 460 ? 18.411  3.7     13.762  1 13.788 ? 452  GLN B N   1 
ATOM   7664 C  CA  . GLN B 1 460 ? 19.541  2.82    13.493  1 11.003 ? 452  GLN B CA  1 
ATOM   7665 C  C   . GLN B 1 460 ? 19.37   2.259   12.074  1 12.362 ? 452  GLN B C   1 
ATOM   7666 O  O   . GLN B 1 460 ? 18.397  2.604   11.352  1 12.664 ? 452  GLN B O   1 
ATOM   7667 C  CB  . GLN B 1 460 ? 19.645  1.793   14.625  1 13.739 ? 452  GLN B CB  1 
ATOM   7668 C  CG  . GLN B 1 460 ? 19.882  2.541   15.927  1 10.267 ? 452  GLN B CG  1 
ATOM   7669 C  CD  . GLN B 1 460 ? 19.729  1.667   17.151  1 12.792 ? 452  GLN B CD  1 
ATOM   7670 O  OE1 . GLN B 1 460 ? 20.094  0.492   17.156  1 13.099 ? 452  GLN B OE1 1 
ATOM   7671 N  NE2 . GLN B 1 460 ? 19.143  2.243   18.184  1 13.691 ? 452  GLN B NE2 1 
ATOM   7672 N  N   . GLU B 1 461 ? 20.231  1.296   11.771  1 11.111 ? 453  GLU B N   1 
ATOM   7673 C  CA  . GLU B 1 461 ? 20.303  0.687   10.429  1 13.179 ? 453  GLU B CA  1 
ATOM   7674 C  C   . GLU B 1 461 ? 18.955  0.115   9.959   1 13.194 ? 453  GLU B C   1 
ATOM   7675 O  O   . GLU B 1 461 ? 18.288  -0.652  10.676  1 13.828 ? 453  GLU B O   1 
ATOM   7676 C  CB  . GLU B 1 461 ? 21.373  -0.412  10.442  1 11.262 ? 453  GLU B CB  1 
ATOM   7677 C  CG  . GLU B 1 461 ? 21.563  -1.03   9.045   1 12.21  ? 453  GLU B CG  1 
ATOM   7678 C  CD  . GLU B 1 461 ? 22.354  -2.296  9.259   1 15.671 ? 453  GLU B CD  1 
ATOM   7679 O  OE1 . GLU B 1 461 ? 21.989  -3.147  10.118  1 17.137 ? 453  GLU B OE1 1 
ATOM   7680 O  OE2 . GLU B 1 461 ? 23.374  -2.426  8.555   1 18.841 ? 453  GLU B OE2 1 
ATOM   7681 N  N   . PRO B 1 462 ? 18.555  0.4     8.69    1 11.125 ? 454  PRO B N   1 
ATOM   7682 C  CA  . PRO B 1 462 ? 17.359  -0.187  8.109   1 13.234 ? 454  PRO B CA  1 
ATOM   7683 C  C   . PRO B 1 462 ? 17.616  -1.587  7.527   1 14.413 ? 454  PRO B C   1 
ATOM   7684 O  O   . PRO B 1 462 ? 18.762  -1.922  7.112   1 13.657 ? 454  PRO B O   1 
ATOM   7685 C  CB  . PRO B 1 462 ? 16.985  0.873   7.012   1 13.82  ? 454  PRO B CB  1 
ATOM   7686 C  CG  . PRO B 1 462 ? 18.401  1.198   6.522   1 11.367 ? 454  PRO B CG  1 
ATOM   7687 C  CD  . PRO B 1 462 ? 19.204  1.392   7.784   1 11.834 ? 454  PRO B CD  1 
ATOM   7688 N  N   . VAL B 1 463 ? 16.542  -2.38   7.568   1 14.879 ? 455  VAL B N   1 
ATOM   7689 C  CA  . VAL B 1 463 ? 16.482  -3.682  6.932   1 17.897 ? 455  VAL B CA  1 
ATOM   7690 C  C   . VAL B 1 463 ? 15.213  -3.725  6.103   1 20.396 ? 455  VAL B C   1 
ATOM   7691 O  O   . VAL B 1 463 ? 14.217  -3.117  6.485   1 16.388 ? 455  VAL B O   1 
ATOM   7692 C  CB  . VAL B 1 463 ? 16.536  -4.899  7.865   1 17.508 ? 455  VAL B CB  1 
ATOM   7693 C  CG1 . VAL B 1 463 ? 17.868  -4.93   8.636   1 17.549 ? 455  VAL B CG1 1 
ATOM   7694 C  CG2 . VAL B 1 463 ? 15.32   -4.932  8.769   1 18.404 ? 455  VAL B CG2 1 
ATOM   7695 N  N   . PHE B 1 464 ? 15.303  -4.468  4.999   1 15.983 ? 456  PHE B N   1 
ATOM   7696 C  CA  . PHE B 1 464 ? 14.248  -4.568  4.006   1 14.883 ? 456  PHE B CA  1 
ATOM   7697 C  C   . PHE B 1 464 ? 13.681  -5.986  3.942   1 14.488 ? 456  PHE B C   1 
ATOM   7698 O  O   . PHE B 1 464 ? 14.434  -6.975  3.922   1 16.834 ? 456  PHE B O   1 
ATOM   7699 C  CB  . PHE B 1 464 ? 14.815  -4.153  2.637   1 14.077 ? 456  PHE B CB  1 
ATOM   7700 C  CG  . PHE B 1 464 ? 13.774  -4.328  1.516   1 19.587 ? 456  PHE B CG  1 
ATOM   7701 C  CD1 . PHE B 1 464 ? 12.697  -3.431  1.4     1 21.676 ? 456  PHE B CD1 1 
ATOM   7702 C  CD2 . PHE B 1 464 ? 13.843  -5.397  0.614   1 22.263 ? 456  PHE B CD2 1 
ATOM   7703 C  CE1 . PHE B 1 464 ? 11.734  -3.577  0.376   1 21.516 ? 456  PHE B CE1 1 
ATOM   7704 C  CE2 . PHE B 1 464 ? 12.877  -5.549  -0.426  1 18.242 ? 456  PHE B CE2 1 
ATOM   7705 C  CZ  . PHE B 1 464 ? 11.813  -4.645  -0.522  1 22.094 ? 456  PHE B CZ  1 
ATOM   7706 N  N   . SER B 1 465 ? 12.345  -6.094  3.85    1 14.882 ? 457  SER B N   1 
ATOM   7707 C  CA  . SER B 1 465 ? 11.658  -7.354  3.607   1 16.649 ? 457  SER B CA  1 
ATOM   7708 C  C   . SER B 1 465 ? 10.778  -7.148  2.373   1 18.401 ? 457  SER B C   1 
ATOM   7709 O  O   . SER B 1 465 ? 9.925   -6.263  2.409   1 20.119 ? 457  SER B O   1 
ATOM   7710 C  CB  . SER B 1 465 ? 10.767  -7.705  4.797   1 19.161 ? 457  SER B CB  1 
ATOM   7711 O  OG  . SER B 1 465 ? 9.862   -8.778  4.506   1 23.891 ? 457  SER B OG  1 
ATOM   7712 N  N   . PRO B 1 466 ? 10.884  -7.963  1.304   1 19.281 ? 458  PRO B N   1 
ATOM   7713 C  CA  . PRO B 1 466 ? 10.012  -7.72   0.153   1 19.862 ? 458  PRO B CA  1 
ATOM   7714 C  C   . PRO B 1 466 ? 8.535   -8.013  0.461   1 21.089 ? 458  PRO B C   1 
ATOM   7715 O  O   . PRO B 1 466 ? 8.246   -8.763  1.4     1 20.773 ? 458  PRO B O   1 
ATOM   7716 C  CB  . PRO B 1 466 ? 10.704  -8.482  -0.968  1 20.752 ? 458  PRO B CB  1 
ATOM   7717 C  CG  . PRO B 1 466 ? 11.44   -9.617  -0.304  1 20.142 ? 458  PRO B CG  1 
ATOM   7718 C  CD  . PRO B 1 466 ? 11.743  -9.162  1.162   1 18.031 ? 458  PRO B CD  1 
ATOM   7719 N  N   . ARG B 1 467 ? 7.625   -7.345  -0.271  1 19.636 ? 459  ARG B N   1 
ATOM   7720 C  CA  . ARG B 1 467 ? 6.185   -7.432  -0.02   1 22.463 ? 459  ARG B CA  1 
ATOM   7721 C  C   . ARG B 1 467 ? 5.724   -8.879  -0.242  1 23.855 ? 459  ARG B C   1 
ATOM   7722 O  O   . ARG B 1 467 ? 4.886   -9.416  0.496   1 26.327 ? 459  ARG B O   1 
ATOM   7723 C  CB  . ARG B 1 467 ? 5.449   -6.391  -0.871  1 21.97  ? 459  ARG B CB  1 
ATOM   7724 C  CG  . ARG B 1 467 ? 3.942   -6.285  -0.62   1 25.274 ? 459  ARG B CG  1 
ATOM   7725 C  CD  . ARG B 1 467 ? 3.187   -5.287  -1.497  1 29.771 ? 459  ARG B CD  1 
ATOM   7726 N  NE  . ARG B 1 467 ? 3.744   -3.922  -1.523  1 27.799 ? 459  ARG B NE  1 
ATOM   7727 C  CZ  . ARG B 1 467 ? 3.878   -3.062  -0.52   1 25.482 ? 459  ARG B CZ  1 
ATOM   7728 N  NH1 . ARG B 1 467 ? 3.172   -3.248  0.586   1 23.483 ? 459  ARG B NH1 1 
ATOM   7729 N  NH2 . ARG B 1 467 ? 4.679   -2.013  -0.633  1 21.078 ? 459  ARG B NH2 1 
ATOM   7730 N  N   . SER B 1 468 ? 6.282   -9.499  -1.289  1 25.369 ? 460  SER B N   1 
ATOM   7731 C  CA  . SER B 1 468 ? 6.081   -10.902 -1.624  1 26.66  ? 460  SER B CA  1 
ATOM   7732 C  C   . SER B 1 468 ? 7.33    -11.361 -2.376  1 25.656 ? 460  SER B C   1 
ATOM   7733 O  O   . SER B 1 468 ? 8.21    -10.54  -2.659  1 28.182 ? 460  SER B O   1 
ATOM   7734 C  CB  . SER B 1 468 ? 4.849   -11.078 -2.471  1 29.109 ? 460  SER B CB  1 
ATOM   7735 O  OG  . SER B 1 468 ? 5.041   -10.35  -3.675  1 30.612 ? 460  SER B OG  1 
ATOM   7736 N  N   . LYS B 1 469 ? 7.411   -12.664 -2.663  1 27.263 ? 461  LYS B N   1 
ATOM   7737 C  CA  . LYS B 1 469 ? 8.626   -13.271 -3.194  1 36.323 ? 461  LYS B CA  1 
ATOM   7738 C  C   . LYS B 1 469 ? 9.031   -12.573 -4.492  1 35.707 ? 461  LYS B C   1 
ATOM   7739 O  O   . LYS B 1 469 ? 10.224  -12.385 -4.713  1 30.796 ? 461  LYS B O   1 
ATOM   7740 C  CB  . LYS B 1 469 ? 8.441   -14.786 -3.397  1 51.212 ? 461  LYS B CB  1 
ATOM   7741 C  CG  . LYS B 1 469 ? 9.695   -15.656 -3.596  1 52.915 ? 461  LYS B CG  1 
ATOM   7742 C  CD  . LYS B 1 469 ? 10.15   -15.938 -5.027  1 53.727 ? 461  LYS B CD  1 
ATOM   7743 C  CE  . LYS B 1 469 ? 9.431   -17.008 -5.793  1 43.758 ? 461  LYS B CE  1 
ATOM   7744 N  NZ  . LYS B 1 469 ? 9.475   -16.675 -7.216  1 45.358 ? 461  LYS B NZ  1 
ATOM   7745 N  N   . ASP B 1 470 ? 8.035   -12.251 -5.341  1 33.5   ? 462  ASP B N   1 
ATOM   7746 C  CA  . ASP B 1 470 ? 8.292   -11.69  -6.665  1 39.994 ? 462  ASP B CA  1 
ATOM   7747 C  C   . ASP B 1 470 ? 7.886   -10.212 -6.746  1 35.172 ? 462  ASP B C   1 
ATOM   7748 O  O   . ASP B 1 470 ? 7.638   -9.697  -7.848  1 35.246 ? 462  ASP B O   1 
ATOM   7749 C  CB  . ASP B 1 470 ? 7.786   -12.586 -7.796  1 51.135 ? 462  ASP B CB  1 
ATOM   7750 C  CG  . ASP B 1 470 ? 6.339   -12.448 -8.262  1 70.607 ? 462  ASP B CG  1 
ATOM   7751 O  OD1 . ASP B 1 470 ? 5.466   -12.008 -7.469  1 76.242 ? 462  ASP B OD1 1 
ATOM   7752 O  OD2 . ASP B 1 470 ? 6.091   -12.752 -9.454  1 84.62  ? 462  ASP B OD2 1 
ATOM   7753 N  N   . ALA B 1 471 ? 7.807   -9.514  -5.593  1 27.811 ? 463  ALA B N   1 
ATOM   7754 C  CA  . ALA B 1 471 ? 7.598   -8.059  -5.564  1 25.203 ? 463  ALA B CA  1 
ATOM   7755 C  C   . ALA B 1 471 ? 8.692   -7.366  -6.385  1 27.688 ? 463  ALA B C   1 
ATOM   7756 O  O   . ALA B 1 471 ? 9.826   -7.844  -6.359  1 28.309 ? 463  ALA B O   1 
ATOM   7757 C  CB  . ALA B 1 471 ? 7.701   -7.55   -4.116  1 25.459 ? 463  ALA B CB  1 
ATOM   7758 N  N   . PRO B 1 472 ? 8.474   -6.212  -7.073  1 26.545 ? 464  PRO B N   1 
ATOM   7759 C  CA  . PRO B 1 472 ? 9.584   -5.427  -7.631  1 27.549 ? 464  PRO B CA  1 
ATOM   7760 C  C   . PRO B 1 472 ? 10.699  -5.161  -6.612  1 28.041 ? 464  PRO B C   1 
ATOM   7761 O  O   . PRO B 1 472 ? 10.429  -5.159  -5.389  1 23.196 ? 464  PRO B O   1 
ATOM   7762 C  CB  . PRO B 1 472 ? 8.942   -4.076  -7.921  1 27.491 ? 464  PRO B CB  1 
ATOM   7763 C  CG  . PRO B 1 472 ? 7.548   -4.528  -8.367  1 30.615 ? 464  PRO B CG  1 
ATOM   7764 C  CD  . PRO B 1 472 ? 7.181   -5.57   -7.348  1 28.537 ? 464  PRO B CD  1 
ATOM   7765 N  N   . GLU B 1 473 ? 11.934  -4.943  -7.118  1 22.687 ? 465  GLU B N   1 
ATOM   7766 C  CA  . GLU B 1 473 ? 13.052  -4.526  -6.245  1 24.891 ? 465  GLU B CA  1 
ATOM   7767 C  C   . GLU B 1 473 ? 12.686  -3.323  -5.362  1 23.751 ? 465  GLU B C   1 
ATOM   7768 O  O   . GLU B 1 473 ? 12.259  -2.281  -5.85   1 23.134 ? 465  GLU B O   1 
ATOM   7769 C  CB  . GLU B 1 473 ? 14.288  -4.148  -7.068  1 29.063 ? 465  GLU B CB  1 
ATOM   7770 C  CG  . GLU B 1 473 ? 15.507  -3.863  -6.196  1 27.391 ? 465  GLU B CG  1 
ATOM   7771 C  CD  . GLU B 1 473 ? 16.757  -3.482  -6.975  1 26.47  ? 465  GLU B CD  1 
ATOM   7772 O  OE1 . GLU B 1 473 ? 16.781  -3.585  -8.232  1 21.799 ? 465  GLU B OE1 1 
ATOM   7773 O  OE2 . GLU B 1 473 ? 17.742  -3.093  -6.292  1 21.521 ? 465  GLU B OE2 1 
ATOM   7774 N  N   . GLY B 1 474 ? 12.839  -3.486  -4.028  1 18.724 ? 466  GLY B N   1 
ATOM   7775 C  CA  . GLY B 1 474 ? 12.65   -2.373  -3.129  1 20.867 ? 466  GLY B CA  1 
ATOM   7776 C  C   . GLY B 1 474 ? 11.188  -2.08   -2.819  1 21.597 ? 466  GLY B C   1 
ATOM   7777 O  O   . GLY B 1 474 ? 10.902  -1.03   -2.282  1 19.329 ? 466  GLY B O   1 
ATOM   7778 N  N   . ASP B 1 475 ? 10.294  -3.009  -3.161  1 24.643 ? 467  ASP B N   1 
ATOM   7779 C  CA  . ASP B 1 475 ? 8.87    -2.927  -2.851  1 21.235 ? 467  ASP B CA  1 
ATOM   7780 C  C   . ASP B 1 475 ? 8.572   -3.798  -1.638  1 16.076 ? 467  ASP B C   1 
ATOM   7781 O  O   . ASP B 1 475 ? 8.725   -5.03   -1.653  1 20.962 ? 467  ASP B O   1 
ATOM   7782 C  CB  . ASP B 1 475 ? 7.989   -3.252  -4.047  1 21.875 ? 467  ASP B CB  1 
ATOM   7783 C  CG  . ASP B 1 475 ? 6.507   -3.073  -3.717  1 29.042 ? 467  ASP B CG  1 
ATOM   7784 O  OD1 . ASP B 1 475 ? 6.085   -1.946  -3.365  1 31.821 ? 467  ASP B OD1 1 
ATOM   7785 O  OD2 . ASP B 1 475 ? 5.797   -4.08   -3.723  1 30.003 ? 467  ASP B OD2 1 
ATOM   7786 N  N   . GLY B 1 476 ? 8.201   -3.168  -0.547  1 17.542 ? 468  GLY B N   1 
ATOM   7787 C  CA  . GLY B 1 476 ? 8.236   -3.929  0.691   1 15.561 ? 468  GLY B CA  1 
ATOM   7788 C  C   . GLY B 1 476 ? 8.221   -3.029  1.904   1 17.077 ? 468  GLY B C   1 
ATOM   7789 O  O   . GLY B 1 476 ? 7.675   -1.914  1.887   1 20.413 ? 468  GLY B O   1 
ATOM   7790 N  N   . PHE B 1 477 ? 8.786   -3.593  2.977   1 16.086 ? 469  PHE B N   1 
ATOM   7791 C  CA  . PHE B 1 477 ? 8.746   -2.992  4.293   1 17.218 ? 469  PHE B CA  1 
ATOM   7792 C  C   . PHE B 1 477 ? 10.179  -2.815  4.76    1 14.916 ? 469  PHE B C   1 
ATOM   7793 O  O   . PHE B 1 477 ? 11.008  -3.692  4.486   1 18.555 ? 469  PHE B O   1 
ATOM   7794 C  CB  . PHE B 1 477 ? 7.945   -3.919  5.188   1 18.316 ? 469  PHE B CB  1 
ATOM   7795 C  CG  . PHE B 1 477 ? 6.494   -3.994  4.692   1 17.039 ? 469  PHE B CG  1 
ATOM   7796 C  CD1 . PHE B 1 477 ? 5.618   -2.921  4.919   1 19.101 ? 469  PHE B CD1 1 
ATOM   7797 C  CD2 . PHE B 1 477 ? 6.065   -5.096  3.941   1 19.837 ? 469  PHE B CD2 1 
ATOM   7798 C  CE1 . PHE B 1 477 ? 4.274   -2.96   4.5     1 18.435 ? 469  PHE B CE1 1 
ATOM   7799 C  CE2 . PHE B 1 477 ? 4.727   -5.138  3.484   1 20.161 ? 469  PHE B CE2 1 
ATOM   7800 C  CZ  . PHE B 1 477 ? 3.855   -4.06   3.766   1 20.771 ? 469  PHE B CZ  1 
ATOM   7801 N  N   . VAL B 1 478 ? 10.434  -1.638  5.37    1 15.019 ? 470  VAL B N   1 
ATOM   7802 C  CA  . VAL B 1 478 ? 11.711  -1.312  5.979   1 14.553 ? 470  VAL B CA  1 
ATOM   7803 C  C   . VAL B 1 478 ? 11.454  -1.208  7.472   1 13.802 ? 470  VAL B C   1 
ATOM   7804 O  O   . VAL B 1 478 ? 10.449  -0.628  7.861   1 17.94  ? 470  VAL B O   1 
ATOM   7805 C  CB  . VAL B 1 478 ? 12.27   -0.002  5.389   1 17.477 ? 470  VAL B CB  1 
ATOM   7806 C  CG1 . VAL B 1 478 ? 13.49   0.515   6.154   1 17.118 ? 470  VAL B CG1 1 
ATOM   7807 C  CG2 . VAL B 1 478 ? 12.562  -0.128  3.887   1 12.681 ? 470  VAL B CG2 1 
ATOM   7808 N  N   . LEU B 1 479 ? 12.356  -1.805  8.259   1 14.799 ? 471  LEU B N   1 
ATOM   7809 C  CA  . LEU B 1 479 ? 12.266  -1.819  9.724   1 14.427 ? 471  LEU B CA  1 
ATOM   7810 C  C   . LEU B 1 479 ? 13.532  -1.166  10.245  1 16.989 ? 471  LEU B C   1 
ATOM   7811 O  O   . LEU B 1 479 ? 14.617  -1.441  9.704   1 15.434 ? 471  LEU B O   1 
ATOM   7812 C  CB  . LEU B 1 479 ? 12.187  -3.26   10.229  1 14.261 ? 471  LEU B CB  1 
ATOM   7813 C  CG  . LEU B 1 479 ? 10.933  -4.078  9.904   1 19.392 ? 471  LEU B CG  1 
ATOM   7814 C  CD1 . LEU B 1 479 ? 10.883  -4.614  8.431   1 20.129 ? 471  LEU B CD1 1 
ATOM   7815 C  CD2 . LEU B 1 479 ? 11.038  -5.226  10.812  1 17.053 ? 471  LEU B CD2 1 
ATOM   7816 N  N   . ALA B 1 480 ? 13.42   -0.397  11.363  1 16.116 ? 472  ALA B N   1 
ATOM   7817 C  CA  . ALA B 1 480 ? 14.63   0.07    11.983  1 14.6   ? 472  ALA B CA  1 
ATOM   7818 C  C   . ALA B 1 480 ? 14.288  0.323   13.465  1 15.454 ? 472  ALA B C   1 
ATOM   7819 O  O   . ALA B 1 480 ? 13.125  0.599   13.792  1 15.443 ? 472  ALA B O   1 
ATOM   7820 C  CB  . ALA B 1 480 ? 15.101  1.326   11.252  1 14.403 ? 472  ALA B CB  1 
ATOM   7821 N  N   . ILE B 1 481 ? 15.329  0.326   14.301  1 14.203 ? 473  ILE B N   1 
ATOM   7822 C  CA  . ILE B 1 481 ? 15.135  0.664   15.705  1 16.04  ? 473  ILE B CA  1 
ATOM   7823 C  C   . ILE B 1 481 ? 15.201  2.187   15.874  1 16.326 ? 473  ILE B C   1 
ATOM   7824 O  O   . ILE B 1 481 ? 16.181  2.814   15.483  1 16.241 ? 473  ILE B O   1 
ATOM   7825 C  CB  . ILE B 1 481 ? 16.141  -0.064  16.622  1 16.142 ? 473  ILE B CB  1 
ATOM   7826 C  CG1 . ILE B 1 481 ? 16.312  -1.595  16.311  1 21.085 ? 473  ILE B CG1 1 
ATOM   7827 C  CG2 . ILE B 1 481 ? 15.863  0.239   18.135  1 11.806 ? 473  ILE B CG2 1 
ATOM   7828 C  CD1 . ILE B 1 481 ? 15.098  -2.485  16.609  1 21.559 ? 473  ILE B CD1 1 
ATOM   7829 N  N   . VAL B 1 482 ? 14.225  2.752   16.601  1 16.849 ? 474  VAL B N   1 
ATOM   7830 C  CA  . VAL B 1 482 ? 14.253  4.147   17.007  1 15.943 ? 474  VAL B CA  1 
ATOM   7831 C  C   . VAL B 1 482 ? 14.482  4.241   18.506  1 14.893 ? 474  VAL B C   1 
ATOM   7832 O  O   . VAL B 1 482 ? 13.802  3.569   19.281  1 15.934 ? 474  VAL B O   1 
ATOM   7833 C  CB  . VAL B 1 482 ? 12.92   4.84    16.673  1 19.305 ? 474  VAL B CB  1 
ATOM   7834 C  CG1 . VAL B 1 482 ? 12.938  6.274   17.174  1 17.255 ? 474  VAL B CG1 1 
ATOM   7835 C  CG2 . VAL B 1 482 ? 12.597  4.719   15.158  1 27.48  ? 474  VAL B CG2 1 
ATOM   7836 N  N   . ASP B 1 483 ? 15.426  5.103   18.887  1 18.005 ? 475  ASP B N   1 
ATOM   7837 C  CA  . ASP B 1 483 ? 15.652  5.461   20.28   1 17.002 ? 475  ASP B CA  1 
ATOM   7838 C  C   . ASP B 1 483 ? 14.722  6.652   20.607  1 20.46  ? 475  ASP B C   1 
ATOM   7839 O  O   . ASP B 1 483 ? 14.813  7.718   20      1 31.346 ? 475  ASP B O   1 
ATOM   7840 C  CB  . ASP B 1 483 ? 17.096  5.923   20.393  1 21.703 ? 475  ASP B CB  1 
ATOM   7841 C  CG  . ASP B 1 483 ? 18.1    4.849   20.002  1 22.972 ? 475  ASP B CG  1 
ATOM   7842 O  OD1 . ASP B 1 483 ? 18.322  4.605   18.783  1 25.415 ? 475  ASP B OD1 1 
ATOM   7843 O  OD2 . ASP B 1 483 ? 18.563  4.208   20.897  1 20.502 ? 475  ASP B OD2 1 
ATOM   7844 N  N   . ARG B 1 484 ? 13.778  6.452   21.522  1 18.947 ? 476  ARG B N   1 
ATOM   7845 C  CA  . ARG B 1 484 ? 12.923  7.535   22.012  1 18.891 ? 476  ARG B CA  1 
ATOM   7846 C  C   . ARG B 1 484 ? 13.633  8.13    23.22   1 18.901 ? 476  ARG B C   1 
ATOM   7847 O  O   . ARG B 1 484 ? 13.458  7.64    24.338  1 18.709 ? 476  ARG B O   1 
ATOM   7848 C  CB  . ARG B 1 484 ? 11.553  6.905   22.337  1 17.789 ? 476  ARG B CB  1 
ATOM   7849 C  CG  . ARG B 1 484 ? 10.768  6.35    21.158  1 23.545 ? 476  ARG B CG  1 
ATOM   7850 C  CD  . ARG B 1 484 ? 10.558  7.335   20.007  1 25.202 ? 476  ARG B CD  1 
ATOM   7851 N  NE  . ARG B 1 484 ? 9.772   8.473   20.497  1 23.699 ? 476  ARG B NE  1 
ATOM   7852 C  CZ  . ARG B 1 484 ? 8.419   8.452   20.568  1 24.355 ? 476  ARG B CZ  1 
ATOM   7853 N  NH1 . ARG B 1 484 ? 7.738   7.425   20.106  1 23.434 ? 476  ARG B NH1 1 
ATOM   7854 N  NH2 . ARG B 1 484 ? 7.771   9.457   21.101  1 21.965 ? 476  ARG B NH2 1 
ATOM   7855 N  N   . LEU B 1 485 ? 14.481  9.145   22.958  1 23.547 ? 477  LEU B N   1 
ATOM   7856 C  CA  . LEU B 1 485 ? 15.537  9.576   23.881  1 25.937 ? 477  LEU B CA  1 
ATOM   7857 C  C   . LEU B 1 485 ? 14.952  10.09   25.204  1 28.673 ? 477  LEU B C   1 
ATOM   7858 O  O   . LEU B 1 485 ? 15.447  9.797   26.289  1 37.243 ? 477  LEU B O   1 
ATOM   7859 C  CB  . LEU B 1 485 ? 16.471  10.578  23.18   1 26.612 ? 477  LEU B CB  1 
ATOM   7860 C  CG  . LEU B 1 485 ? 17.231  10.083  21.928  1 28.352 ? 477  LEU B CG  1 
ATOM   7861 C  CD1 . LEU B 1 485 ? 18.07   11.192  21.242  1 28.524 ? 477  LEU B CD1 1 
ATOM   7862 C  CD2 . LEU B 1 485 ? 18.164  8.883   22.145  1 25.947 ? 477  LEU B CD2 1 
ATOM   7863 N  N   . ASP B 1 486 ? 13.843  10.807  25.108  1 31.478 ? 478  ASP B N   1 
ATOM   7864 C  CA  . ASP B 1 486 ? 13.127  11.396  26.235  1 36.004 ? 478  ASP B CA  1 
ATOM   7865 C  C   . ASP B 1 486 ? 12.26   10.389  27.007  1 34.15  ? 478  ASP B C   1 
ATOM   7866 O  O   . ASP B 1 486 ? 11.838  10.667  28.128  1 30.19  ? 478  ASP B O   1 
ATOM   7867 C  CB  . ASP B 1 486 ? 12.256  12.552  25.75   1 31.553 ? 478  ASP B CB  1 
ATOM   7868 C  CG  . ASP B 1 486 ? 11.217  12.19   24.704  1 36.509 ? 478  ASP B CG  1 
ATOM   7869 O  OD1 . ASP B 1 486 ? 11.393  11.162  24.034  1 33.517 ? 478  ASP B OD1 1 
ATOM   7870 O  OD2 . ASP B 1 486 ? 10.188  12.888  24.636  1 39.647 ? 478  ASP B OD2 1 
ATOM   7871 N  N   . LEU B 1 487 ? 11.988  9.211   26.426  1 32.654 ? 479  LEU B N   1 
ATOM   7872 C  CA  . LEU B 1 487 ? 11.059  8.26    27.037  1 28.321 ? 479  LEU B CA  1 
ATOM   7873 C  C   . LEU B 1 487 ? 11.762  7.031   27.616  1 29.351 ? 479  LEU B C   1 
ATOM   7874 O  O   . LEU B 1 487 ? 11.092  6.141   28.153  1 28.507 ? 479  LEU B O   1 
ATOM   7875 C  CB  . LEU B 1 487 ? 10.029  7.894   25.961  1 25.447 ? 479  LEU B CB  1 
ATOM   7876 C  CG  . LEU B 1 487 ? 9.122   9.026   25.462  1 25.703 ? 479  LEU B CG  1 
ATOM   7877 C  CD1 . LEU B 1 487 ? 8.261   8.53    24.338  1 23.915 ? 479  LEU B CD1 1 
ATOM   7878 C  CD2 . LEU B 1 487 ? 8.216   9.546   26.605  1 24.959 ? 479  LEU B CD2 1 
ATOM   7879 N  N   . ASN B 1 488 ? 13.099  6.956   27.475  1 21.978 ? 480  ASN B N   1 
ATOM   7880 C  CA  . ASN B 1 488 ? 13.87   5.799   27.901  1 24.166 ? 480  ASN B CA  1 
ATOM   7881 C  C   . ASN B 1 488 ? 13.263  4.513   27.319  1 21.885 ? 480  ASN B C   1 
ATOM   7882 O  O   . ASN B 1 488 ? 12.993  3.563   28.045  1 20.42  ? 480  ASN B O   1 
ATOM   7883 C  CB  . ASN B 1 488 ? 14.139  5.773   29.421  1 24.054 ? 480  ASN B CB  1 
ATOM   7884 C  CG  . ASN B 1 488 ? 15.118  4.7     29.905  1 34.415 ? 480  ASN B CG  1 
ATOM   7885 O  OD1 . ASN B 1 488 ? 16.163  4.46    29.286  1 21.631 ? 480  ASN B OD1 1 
ATOM   7886 N  ND2 . ASN B 1 488 ? 14.868  4.047   31.041  1 29.737 ? 480  ASN B ND2 1 
ATOM   7887 N  N   . ARG B 1 489 ? 13.001  4.471   25.994  1 17.029 ? 481  ARG B N   1 
ATOM   7888 C  CA  . ARG B 1 489 ? 12.603  3.202   25.436  1 15.641 ? 481  ARG B CA  1 
ATOM   7889 C  C   . ARG B 1 489 ? 13.028  3.182   23.965  1 18.566 ? 481  ARG B C   1 
ATOM   7890 O  O   . ARG B 1 489 ? 13.434  4.217   23.396  1 15.936 ? 481  ARG B O   1 
ATOM   7891 C  CB  . ARG B 1 489 ? 11.079  2.998   25.566  1 23.445 ? 481  ARG B CB  1 
ATOM   7892 C  CG  . ARG B 1 489 ? 10.195  3.745   24.577  1 19.728 ? 481  ARG B CG  1 
ATOM   7893 C  CD  . ARG B 1 489 ? 8.743   3.424   24.837  1 26.514 ? 481  ARG B CD  1 
ATOM   7894 N  NE  . ARG B 1 489 ? 7.924   4.028   23.783  1 31.438 ? 481  ARG B NE  1 
ATOM   7895 C  CZ  . ARG B 1 489 ? 6.999   4.925   24.051  1 32.832 ? 481  ARG B CZ  1 
ATOM   7896 N  NH1 . ARG B 1 489 ? 6.752   5.281   25.31   1 35.124 ? 481  ARG B NH1 1 
ATOM   7897 N  NH2 . ARG B 1 489 ? 6.389   5.511   23.029  1 31.258 ? 481  ARG B NH2 1 
ATOM   7898 N  N   . SER B 1 490 ? 13.02   1.978   23.412  1 16.264 ? 482  SER B N   1 
ATOM   7899 C  CA  . SER B 1 490 ? 13.364  1.812   22.007  1 13.606 ? 482  SER B CA  1 
ATOM   7900 C  C   . SER B 1 490 ? 12.13   1.254   21.317  1 14.981 ? 482  SER B C   1 
ATOM   7901 O  O   . SER B 1 490 ? 11.324  0.56    21.945  1 13.982 ? 482  SER B O   1 
ATOM   7902 C  CB  . SER B 1 490 ? 14.504  0.818   21.907  1 14.811 ? 482  SER B CB  1 
ATOM   7903 O  OG  . SER B 1 490 ? 15.674  1.322   22.566  1 15.73  ? 482  SER B OG  1 
ATOM   7904 N  N   . GLU B 1 491 ? 12.026  1.437   19.985  1 15.247 ? 483  GLU B N   1 
ATOM   7905 C  CA  . GLU B 1 491 ? 10.841  0.965   19.304  1 15.223 ? 483  GLU B CA  1 
ATOM   7906 C  C   . GLU B 1 491 ? 11.299  0.526   17.918  1 15.997 ? 483  GLU B C   1 
ATOM   7907 O  O   . GLU B 1 491 ? 12.341  0.965   17.493  1 17.207 ? 483  GLU B O   1 
ATOM   7908 C  CB  . GLU B 1 491 ? 9.767   2.04    19.024  1 18.355 ? 483  GLU B CB  1 
ATOM   7909 C  CG  . GLU B 1 491 ? 9.482   2.98    20.19   1 23.402 ? 483  GLU B CG  1 
ATOM   7910 C  CD  . GLU B 1 491 ? 8.244   3.853   20.088  1 27.186 ? 483  GLU B CD  1 
ATOM   7911 O  OE1 . GLU B 1 491 ? 7.995   4.419   19.009  1 27.226 ? 483  GLU B OE1 1 
ATOM   7912 O  OE2 . GLU B 1 491 ? 7.571   3.988   21.144  1 35.284 ? 483  GLU B OE2 1 
ATOM   7913 N  N   . VAL B 1 492 ? 10.576  -0.391  17.285  1 13.852 ? 484  VAL B N   1 
ATOM   7914 C  CA  . VAL B 1 492 ? 10.859  -0.763  15.893  1 15.603 ? 484  VAL B CA  1 
ATOM   7915 C  C   . VAL B 1 492 ? 9.787   -0.097  15.045  1 18.072 ? 484  VAL B C   1 
ATOM   7916 O  O   . VAL B 1 492 ? 8.576   -0.338  15.215  1 17.245 ? 484  VAL B O   1 
ATOM   7917 C  CB  . VAL B 1 492 ? 10.845  -2.3    15.653  1 17.236 ? 484  VAL B CB  1 
ATOM   7918 C  CG1 . VAL B 1 492 ? 11.412  -2.696  14.285  1 16.815 ? 484  VAL B CG1 1 
ATOM   7919 C  CG2 . VAL B 1 492 ? 11.522  -3.072  16.807  1 16.131 ? 484  VAL B CG2 1 
ATOM   7920 N  N   . VAL B 1 493 ? 10.237  0.685   14.068  1 17.398 ? 485  VAL B N   1 
ATOM   7921 C  CA  . VAL B 1 493 ? 9.313   1.291   13.154  1 16.497 ? 485  VAL B CA  1 
ATOM   7922 C  C   . VAL B 1 493 ? 9.244   0.361   11.952  1 16.592 ? 485  VAL B C   1 
ATOM   7923 O  O   . VAL B 1 493 ? 10.215  -0.345  11.643  1 15.899 ? 485  VAL B O   1 
ATOM   7924 C  CB  . VAL B 1 493 ? 9.754   2.739   12.81   1 22.097 ? 485  VAL B CB  1 
ATOM   7925 C  CG1 . VAL B 1 493 ? 11.091  2.834   12.064  1 18.955 ? 485  VAL B CG1 1 
ATOM   7926 C  CG2 . VAL B 1 493 ? 8.703   3.467   12.031  1 25.152 ? 485  VAL B CG2 1 
ATOM   7927 N  N   . VAL B 1 494 ? 8.076   0.416   11.292  1 17.302 ? 486  VAL B N   1 
ATOM   7928 C  CA  . VAL B 1 494 ? 7.819   -0.347  10.099  1 17.863 ? 486  VAL B CA  1 
ATOM   7929 C  C   . VAL B 1 494 ? 7.295   0.651   9.084   1 18.023 ? 486  VAL B C   1 
ATOM   7930 O  O   . VAL B 1 494 ? 6.295   1.347   9.336   1 18.071 ? 486  VAL B O   1 
ATOM   7931 C  CB  . VAL B 1 494 ? 6.745   -1.42   10.41   1 18.366 ? 486  VAL B CB  1 
ATOM   7932 C  CG1 . VAL B 1 494 ? 6.465   -2.316  9.201   1 18.789 ? 486  VAL B CG1 1 
ATOM   7933 C  CG2 . VAL B 1 494 ? 7.096   -2.242  11.664  1 21.293 ? 486  VAL B CG2 1 
ATOM   7934 N  N   . ILE B 1 495 ? 7.948   0.658   7.924   1 18.161 ? 487  ILE B N   1 
ATOM   7935 C  CA  . ILE B 1 495 ? 7.581   1.632   6.904   1 19.462 ? 487  ILE B CA  1 
ATOM   7936 C  C   . ILE B 1 495 ? 7.254   0.874   5.625   1 18.925 ? 487  ILE B C   1 
ATOM   7937 O  O   . ILE B 1 495 ? 8.015   0.012   5.245   1 17.765 ? 487  ILE B O   1 
ATOM   7938 C  CB  . ILE B 1 495 ? 8.744   2.627   6.69    1 21.303 ? 487  ILE B CB  1 
ATOM   7939 C  CG1 . ILE B 1 495 ? 9.012   3.505   7.916   1 15.769 ? 487  ILE B CG1 1 
ATOM   7940 C  CG2 . ILE B 1 495 ? 8.579   3.496   5.41    1 17.186 ? 487  ILE B CG2 1 
ATOM   7941 C  CD1 . ILE B 1 495 ? 10.482  3.915   7.929   1 20.971 ? 487  ILE B CD1 1 
ATOM   7942 N  N   . ASP B 1 496 ? 6.167   1.288   4.95    1 18.811 ? 488  ASP B N   1 
ATOM   7943 C  CA  . ASP B 1 496 ? 5.859   0.711   3.655   1 20.842 ? 488  ASP B CA  1 
ATOM   7944 C  C   . ASP B 1 496 ? 6.546   1.541   2.574   1 18.212 ? 488  ASP B C   1 
ATOM   7945 O  O   . ASP B 1 496 ? 6.412   2.742   2.582   1 20.441 ? 488  ASP B O   1 
ATOM   7946 C  CB  . ASP B 1 496 ? 4.343   0.676   3.469   1 19.634 ? 488  ASP B CB  1 
ATOM   7947 C  CG  . ASP B 1 496 ? 3.859   -0.097  2.255   1 23.099 ? 488  ASP B CG  1 
ATOM   7948 O  OD1 . ASP B 1 496 ? 4.475   0.078   1.17    1 20.499 ? 488  ASP B OD1 1 
ATOM   7949 O  OD2 . ASP B 1 496 ? 2.887   -0.853  2.406   1 27.264 ? 488  ASP B OD2 1 
ATOM   7950 N  N   . THR B 1 497 ? 7.311   0.909   1.669   1 20.388 ? 489  THR B N   1 
ATOM   7951 C  CA  . THR B 1 497 ? 8.042   1.646   0.64    1 21.901 ? 489  THR B CA  1 
ATOM   7952 C  C   . THR B 1 497 ? 7.113   2.431   -0.288  1 21.69  ? 489  THR B C   1 
ATOM   7953 O  O   . THR B 1 497 ? 7.561   3.401   -0.894  1 20.247 ? 489  THR B O   1 
ATOM   7954 C  CB  . THR B 1 497 ? 9.021   0.785   -0.169  1 21.841 ? 489  THR B CB  1 
ATOM   7955 O  OG1 . THR B 1 497 ? 8.157   -0.147  -0.789  1 23.756 ? 489  THR B OG1 1 
ATOM   7956 C  CG2 . THR B 1 497 ? 10.153  0.203   0.663   1 23.057 ? 489  THR B CG2 1 
ATOM   7957 N  N   . ARG B 1 498 ? 5.819   2.091   -0.31   1 20.936 ? 490  ARG B N   1 
ATOM   7958 C  CA  . ARG B 1 498 ? 4.879   2.858   -1.113  1 28.166 ? 490  ARG B CA  1 
ATOM   7959 C  C   . ARG B 1 498 ? 4.683   4.249   -0.506  1 28.483 ? 490  ARG B C   1 
ATOM   7960 O  O   . ARG B 1 498 ? 4.357   5.186   -1.216  1 25.944 ? 490  ARG B O   1 
ATOM   7961 C  CB  . ARG B 1 498 ? 3.572   2.092   -1.362  1 34.73  ? 490  ARG B CB  1 
ATOM   7962 C  CG  . ARG B 1 498 ? 3.597   0.825   -2.207  1 37.744 ? 490  ARG B CG  1 
ATOM   7963 C  CD  . ARG B 1 498 ? 2.257   0.208   -1.86   1 44.794 ? 490  ARG B CD  1 
ATOM   7964 N  NE  . ARG B 1 498 ? 1.99    -1.142  -2.374  1 57.107 ? 490  ARG B NE  1 
ATOM   7965 C  CZ  . ARG B 1 498 ? 0.945   -1.918  -2.048  1 62.55  ? 490  ARG B CZ  1 
ATOM   7966 N  NH1 . ARG B 1 498 ? 0.019   -1.512  -1.189  1 59.398 ? 490  ARG B NH1 1 
ATOM   7967 N  NH2 . ARG B 1 498 ? 0.806   -3.114  -2.594  1 66.562 ? 490  ARG B NH2 1 
ATOM   7968 N  N   . ASP B 1 499 ? 4.969   4.419   0.801   1 22.501 ? 491  ASP B N   1 
ATOM   7969 C  CA  . ASP B 1 499 ? 5.069   5.768   1.315   1 22.255 ? 491  ASP B CA  1 
ATOM   7970 C  C   . ASP B 1 499 ? 6.173   5.842   2.369   1 25.48  ? 491  ASP B C   1 
ATOM   7971 O  O   . ASP B 1 499 ? 5.891   5.721   3.566   1 26.141 ? 491  ASP B O   1 
ATOM   7972 C  CB  . ASP B 1 499 ? 3.741   6.34    1.779   1 29.229 ? 491  ASP B CB  1 
ATOM   7973 C  CG  . ASP B 1 499 ? 3.827   7.783   2.256   1 37.265 ? 491  ASP B CG  1 
ATOM   7974 O  OD1 . ASP B 1 499 ? 4.903   8.444   2.086   1 36.865 ? 491  ASP B OD1 1 
ATOM   7975 O  OD2 . ASP B 1 499 ? 2.843   8.233   2.851   1 43.619 ? 491  ASP B OD2 1 
ATOM   7976 N  N   . PHE B 1 500 ? 7.393   6.102   1.879   1 20.528 ? 492  PHE B N   1 
ATOM   7977 C  CA  . PHE B 1 500 ? 8.615   6.057   2.674   1 22.716 ? 492  PHE B CA  1 
ATOM   7978 C  C   . PHE B 1 500 ? 8.663   7.09    3.814   1 24.659 ? 492  PHE B C   1 
ATOM   7979 O  O   . PHE B 1 500 ? 9.357   6.836   4.808   1 21.859 ? 492  PHE B O   1 
ATOM   7980 C  CB  . PHE B 1 500 ? 9.836   6.088   1.772   1 22.695 ? 492  PHE B CB  1 
ATOM   7981 C  CG  . PHE B 1 500 ? 11.072  5.574   2.5     1 22.572 ? 492  PHE B CG  1 
ATOM   7982 C  CD1 . PHE B 1 500 ? 11.241  4.204   2.75    1 22.528 ? 492  PHE B CD1 1 
ATOM   7983 C  CD2 . PHE B 1 500 ? 12.027  6.464   2.973   1 21.673 ? 492  PHE B CD2 1 
ATOM   7984 C  CE1 . PHE B 1 500 ? 12.392  3.731   3.387   1 22.241 ? 492  PHE B CE1 1 
ATOM   7985 C  CE2 . PHE B 1 500 ? 13.173  5.994   3.625   1 20.702 ? 492  PHE B CE2 1 
ATOM   7986 C  CZ  . PHE B 1 500 ? 13.342  4.619   3.833   1 20.061 ? 492  PHE B CZ  1 
ATOM   7987 N  N   . THR B 1 501 ? 7.868   8.194   3.698   1 22.529 ? 493  THR B N   1 
ATOM   7988 C  CA  . THR B 1 501 ? 7.849   9.251   4.695   1 23.297 ? 493  THR B CA  1 
ATOM   7989 C  C   . THR B 1 501 ? 7.142   8.849   6.002   1 24.709 ? 493  THR B C   1 
ATOM   7990 O  O   . THR B 1 501 ? 7.321   9.536   6.995   1 24.497 ? 493  THR B O   1 
ATOM   7991 C  CB  . THR B 1 501 ? 7.37    10.58   4.091   1 23.165 ? 493  THR B CB  1 
ATOM   7992 O  OG1 . THR B 1 501 ? 5.953   10.527  4.104   1 24.834 ? 493  THR B OG1 1 
ATOM   7993 C  CG2 . THR B 1 501 ? 7.83    10.786  2.653   1 20.268 ? 493  THR B CG2 1 
ATOM   7994 N  N   . LYS B 1 502 ? 6.372   7.741   6.024   1 26.818 ? 494  LYS B N   1 
ATOM   7995 C  CA  . LYS B 1 502 ? 5.415   7.447   7.098   1 30.853 ? 494  LYS B CA  1 
ATOM   7996 C  C   . LYS B 1 502 ? 5.575   6.032   7.654   1 21.644 ? 494  LYS B C   1 
ATOM   7997 O  O   . LYS B 1 502 ? 5.593   5.058   6.906   1 23.429 ? 494  LYS B O   1 
ATOM   7998 C  CB  . LYS B 1 502 ? 4.024   7.581   6.468   1 33.361 ? 494  LYS B CB  1 
ATOM   7999 C  CG  . LYS B 1 502 ? 2.782   7.476   7.333   1 44.603 ? 494  LYS B CG  1 
ATOM   8000 C  CD  . LYS B 1 502 ? 1.633   8.094   6.541   1 45.99  ? 494  LYS B CD  1 
ATOM   8001 C  CE  . LYS B 1 502 ? 0.259   7.512   6.682   1 51.482 ? 494  LYS B CE  1 
ATOM   8002 N  NZ  . LYS B 1 502 ? -0.307  7.564   8.031   1 45.414 ? 494  LYS B NZ  1 
ATOM   8003 N  N   . ALA B 1 503 ? 5.563   5.91    8.988   1 21.822 ? 495  ALA B N   1 
ATOM   8004 C  CA  . ALA B 1 503 ? 5.475   4.605   9.631   1 19.718 ? 495  ALA B CA  1 
ATOM   8005 C  C   . ALA B 1 503 ? 4.054   4.051   9.589   1 23.005 ? 495  ALA B C   1 
ATOM   8006 O  O   . ALA B 1 503 ? 3.117   4.768   9.95    1 25.51  ? 495  ALA B O   1 
ATOM   8007 C  CB  . ALA B 1 503 ? 5.883   4.761   11.101  1 21.596 ? 495  ALA B CB  1 
ATOM   8008 N  N   . VAL B 1 504 ? 3.91    2.771   9.201   1 17.908 ? 496  VAL B N   1 
ATOM   8009 C  CA  . VAL B 1 504 ? 2.646   2.05    9.268   1 18.849 ? 496  VAL B CA  1 
ATOM   8010 C  C   . VAL B 1 504 ? 2.444   1.495   10.677  1 22.155 ? 496  VAL B C   1 
ATOM   8011 O  O   . VAL B 1 504 ? 1.307   1.403   11.153  1 21.68  ? 496  VAL B O   1 
ATOM   8012 C  CB  . VAL B 1 504 ? 2.326   0.983   8.212   1 19.85  ? 496  VAL B CB  1 
ATOM   8013 C  CG1 . VAL B 1 504 ? 2.173   1.634   6.837   1 21.187 ? 496  VAL B CG1 1 
ATOM   8014 C  CG2 . VAL B 1 504 ? 3.362   -0.135  8.167   1 21.314 ? 496  VAL B CG2 1 
ATOM   8015 N  N   . ALA B 1 505 ? 3.548   1.141   11.333  1 17.891 ? 497  ALA B N   1 
ATOM   8016 C  CA  . ALA B 1 505 ? 3.415   0.551   12.657  1 19.92  ? 497  ALA B CA  1 
ATOM   8017 C  C   . ALA B 1 505 ? 4.645   0.866   13.512  1 17.092 ? 497  ALA B C   1 
ATOM   8018 O  O   . ALA B 1 505 ? 5.682   1.257   12.996  1 17.953 ? 497  ALA B O   1 
ATOM   8019 C  CB  . ALA B 1 505 ? 3.215   -0.958  12.545  1 23.73  ? 497  ALA B CB  1 
ATOM   8020 N  N   . ALA B 1 506 ? 4.488   0.691   14.825  1 17.843 ? 498  ALA B N   1 
ATOM   8021 C  CA  . ALA B 1 506 ? 5.6     0.828   15.746  1 17.865 ? 498  ALA B CA  1 
ATOM   8022 C  C   . ALA B 1 506 ? 5.553   -0.311  16.774  1 19.663 ? 498  ALA B C   1 
ATOM   8023 O  O   . ALA B 1 506 ? 4.509   -0.467  17.381  1 19.309 ? 498  ALA B O   1 
ATOM   8024 C  CB  . ALA B 1 506 ? 5.603   2.207   16.408  1 19.764 ? 498  ALA B CB  1 
ATOM   8025 N  N   . VAL B 1 507 ? 6.655   -1.096  16.934  1 13.894 ? 499  VAL B N   1 
ATOM   8026 C  CA  . VAL B 1 507 ? 6.71    -2.119  17.934  1 15.923 ? 499  VAL B CA  1 
ATOM   8027 C  C   . VAL B 1 507 ? 7.308   -1.434  19.164  1 17.362 ? 499  VAL B C   1 
ATOM   8028 O  O   . VAL B 1 507 ? 8.479   -1.01   19.138  1 20.967 ? 499  VAL B O   1 
ATOM   8029 C  CB  . VAL B 1 507 ? 7.586   -3.309  17.461  1 17.838 ? 499  VAL B CB  1 
ATOM   8030 C  CG1 . VAL B 1 507 ? 7.607   -4.411  18.532  1 16.735 ? 499  VAL B CG1 1 
ATOM   8031 C  CG2 . VAL B 1 507 ? 7.075   -3.949  16.164  1 14.888 ? 499  VAL B CG2 1 
ATOM   8032 N  N   . GLN B 1 508 ? 6.582   -1.464  20.278  1 14.808 ? 500  GLN B N   1 
ATOM   8033 C  CA  . GLN B 1 508 ? 6.915   -0.6    21.388  1 14.95  ? 500  GLN B CA  1 
ATOM   8034 C  C   . GLN B 1 508 ? 7.439   -1.453  22.516  1 15.463 ? 500  GLN B C   1 
ATOM   8035 O  O   . GLN B 1 508 ? 6.627   -2.061  23.174  1 12.305 ? 500  GLN B O   1 
ATOM   8036 C  CB  . GLN B 1 508 ? 5.676   0.194   21.794  1 20.377 ? 500  GLN B CB  1 
ATOM   8037 C  CG  . GLN B 1 508 ? 5.853   1.196   22.941  1 22.052 ? 500  GLN B CG  1 
ATOM   8038 C  CD  . GLN B 1 508 ? 4.54    1.822   23.381  1 22.141 ? 500  GLN B CD  1 
ATOM   8039 O  OE1 . GLN B 1 508 ? 3.658   2.017   22.564  1 18.812 ? 500  GLN B OE1 1 
ATOM   8040 N  NE2 . GLN B 1 508 ? 4.321   2.045   24.677  1 18.223 ? 500  GLN B NE2 1 
ATOM   8041 N  N   . LEU B 1 509 ? 8.771   -1.48   22.713  1 12.905 ? 501  LEU B N   1 
ATOM   8042 C  CA  . LEU B 1 509 ? 9.307   -2.145  23.894  1 14.614 ? 501  LEU B CA  1 
ATOM   8043 C  C   . LEU B 1 509 ? 8.928   -1.353  25.135  1 14.147 ? 501  LEU B C   1 
ATOM   8044 O  O   . LEU B 1 509 ? 8.8     -0.137  25.074  1 16.283 ? 501  LEU B O   1 
ATOM   8045 C  CB  . LEU B 1 509 ? 10.829  -2.372  23.82   1 13.05  ? 501  LEU B CB  1 
ATOM   8046 C  CG  . LEU B 1 509 ? 11.324  -3.439  22.845  1 14.245 ? 501  LEU B CG  1 
ATOM   8047 C  CD1 . LEU B 1 509 ? 12.852  -3.318  22.702  1 16.445 ? 501  LEU B CD1 1 
ATOM   8048 C  CD2 . LEU B 1 509 ? 10.98   -4.86   23.265  1 17.816 ? 501  LEU B CD2 1 
ATOM   8049 N  N   . PRO B 1 510 ? 8.835   -1.989  26.342  1 14.57  ? 502  PRO B N   1 
ATOM   8050 C  CA  . PRO B 1 510 ? 8.652   -1.237  27.555  1 16.244 ? 502  PRO B CA  1 
ATOM   8051 C  C   . PRO B 1 510 ? 9.954   -0.661  28.107  1 22.396 ? 502  PRO B C   1 
ATOM   8052 O  O   . PRO B 1 510 ? 9.982   -0.147  29.219  1 28.03  ? 502  PRO B O   1 
ATOM   8053 C  CB  . PRO B 1 510 ? 8.161   -2.282  28.552  1 14.685 ? 502  PRO B CB  1 
ATOM   8054 C  CG  . PRO B 1 510 ? 8.775   -3.586  28.109  1 14.568 ? 502  PRO B CG  1 
ATOM   8055 C  CD  . PRO B 1 510 ? 8.869   -3.439  26.537  1 13.398 ? 502  PRO B CD  1 
ATOM   8056 N  N   . PHE B 1 511 ? 11.045  -0.78   27.359  1 21.717 ? 503  PHE B N   1 
ATOM   8057 C  CA  . PHE B 1 511 ? 12.375  -0.348  27.801  1 15.908 ? 503  PHE B CA  1 
ATOM   8058 C  C   . PHE B 1 511 ? 13.215  0.023   26.593  1 19.084 ? 503  PHE B C   1 
ATOM   8059 O  O   . PHE B 1 511 ? 12.781  -0.276  25.477  1 15.696 ? 503  PHE B O   1 
ATOM   8060 C  CB  . PHE B 1 511 ? 13.012  -1.403  28.716  1 16.806 ? 503  PHE B CB  1 
ATOM   8061 C  CG  . PHE B 1 511 ? 13.043  -2.825  28.192  1 16.396 ? 503  PHE B CG  1 
ATOM   8062 C  CD1 . PHE B 1 511 ? 13.472  -3.161  26.89   1 19.174 ? 503  PHE B CD1 1 
ATOM   8063 C  CD2 . PHE B 1 511 ? 12.615  -3.872  29.002  1 17.025 ? 503  PHE B CD2 1 
ATOM   8064 C  CE1 . PHE B 1 511 ? 13.511  -4.487  26.467  1 18.648 ? 503  PHE B CE1 1 
ATOM   8065 C  CE2 . PHE B 1 511 ? 12.646  -5.2    28.547  1 17.134 ? 503  PHE B CE2 1 
ATOM   8066 C  CZ  . PHE B 1 511 ? 13.081  -5.505  27.3    1 18.877 ? 503  PHE B CZ  1 
ATOM   8067 N  N   . ALA B 1 512 ? 14.387  0.652   26.86   1 17.184 ? 504  ALA B N   1 
ATOM   8068 C  CA  . ALA B 1 512 ? 15.431  0.907   25.874  1 15.251 ? 504  ALA B CA  1 
ATOM   8069 C  C   . ALA B 1 512 ? 16.444  -0.231  25.81   1 14.871 ? 504  ALA B C   1 
ATOM   8070 O  O   . ALA B 1 512 ? 16.782  -0.814  26.831  1 13.579 ? 504  ALA B O   1 
ATOM   8071 C  CB  . ALA B 1 512 ? 16.098  2.214   26.212  1 14.29  ? 504  ALA B CB  1 
ATOM   8072 N  N   . ILE B 1 513 ? 16.92   -0.517  24.591  1 10.999 ? 505  ILE B N   1 
ATOM   8073 C  CA  . ILE B 1 513 ? 18.052  -1.398  24.348  1 12.936 ? 505  ILE B CA  1 
ATOM   8074 C  C   . ILE B 1 513 ? 19.234  -0.532  23.821  1 12.914 ? 505  ILE B C   1 
ATOM   8075 O  O   . ILE B 1 513 ? 19.069  0.633   23.425  1 13.896 ? 505  ILE B O   1 
ATOM   8076 C  CB  . ILE B 1 513 ? 17.669  -2.577  23.435  1 11.64  ? 505  ILE B CB  1 
ATOM   8077 C  CG1 . ILE B 1 513 ? 17.298  -2.083  21.989  1 12.772 ? 505  ILE B CG1 1 
ATOM   8078 C  CG2 . ILE B 1 513 ? 16.519  -3.388  24.047  1 13.779 ? 505  ILE B CG2 1 
ATOM   8079 C  CD1 . ILE B 1 513 ? 17.087  -3.198  20.936  1 17.132 ? 505  ILE B CD1 1 
ATOM   8080 N  N   . ARG B 1 514 ? 20.453  -1.066  23.843  1 12.021 ? 506  ARG B N   1 
ATOM   8081 C  CA  . ARG B 1 514 ? 21.661  -0.401  23.373  1 12.729 ? 506  ARG B CA  1 
ATOM   8082 C  C   . ARG B 1 514 ? 21.444  0       21.911  1 13.258 ? 506  ARG B C   1 
ATOM   8083 O  O   . ARG B 1 514 ? 20.7    -0.686  21.224  1 11.749 ? 506  ARG B O   1 
ATOM   8084 C  CB  . ARG B 1 514 ? 22.829  -1.397  23.309  1 11.806 ? 506  ARG B CB  1 
ATOM   8085 C  CG  . ARG B 1 514 ? 23.485  -1.457  24.674  1 14.245 ? 506  ARG B CG  1 
ATOM   8086 C  CD  . ARG B 1 514 ? 24.417  -0.238  24.843  1 15.548 ? 506  ARG B CD  1 
ATOM   8087 N  NE  . ARG B 1 514 ? 25.202  -0.385  26.086  1 14.549 ? 506  ARG B NE  1 
ATOM   8088 C  CZ  . ARG B 1 514 ? 26.132  0.459   26.498  1 17.702 ? 506  ARG B CZ  1 
ATOM   8089 N  NH1 . ARG B 1 514 ? 26.291  1.654   25.91   1 17.347 ? 506  ARG B NH1 1 
ATOM   8090 N  NH2 . ARG B 1 514 ? 26.839  0.165   27.583  1 15.231 ? 506  ARG B NH2 1 
ATOM   8091 N  N   . SER B 1 515 ? 22.042  1.128   21.5    1 14.195 ? 507  SER B N   1 
ATOM   8092 C  CA  . SER B 1 515 ? 22.097  1.39    20.044  1 11.645 ? 507  SER B CA  1 
ATOM   8093 C  C   . SER B 1 515 ? 23.073  0.359   19.491  1 13.672 ? 507  SER B C   1 
ATOM   8094 O  O   . SER B 1 515 ? 24.145  0.14    20.08   1 14.797 ? 507  SER B O   1 
ATOM   8095 C  CB  . SER B 1 515 ? 22.512  2.802   19.759  1 12.302 ? 507  SER B CB  1 
ATOM   8096 O  OG  . SER B 1 515 ? 22.444  3.148   18.358  1 14.339 ? 507  SER B OG  1 
ATOM   8097 N  N   . GLY B 1 516 ? 22.683  -0.305  18.387  1 14.152 ? 508  GLY B N   1 
ATOM   8098 C  CA  . GLY B 1 516 ? 23.537  -1.392  17.929  1 15.105 ? 508  GLY B CA  1 
ATOM   8099 C  C   . GLY B 1 516 ? 24.297  -1.091  16.644  1 13.187 ? 508  GLY B C   1 
ATOM   8100 O  O   . GLY B 1 516 ? 24.565  0.059   16.314  1 14.684 ? 508  GLY B O   1 
ATOM   8101 N  N   . ILE B 1 517 ? 24.739  -2.175  16.027  1 12.358 ? 509  ILE B N   1 
ATOM   8102 C  CA  . ILE B 1 517 ? 25.638  -2.077  14.902  1 14.955 ? 509  ILE B CA  1 
ATOM   8103 C  C   . ILE B 1 517 ? 24.806  -2.464  13.677  1 15.195 ? 509  ILE B C   1 
ATOM   8104 O  O   . ILE B 1 517 ? 24.022  -1.639  13.223  1 16.362 ? 509  ILE B O   1 
ATOM   8105 C  CB  . ILE B 1 517 ? 26.956  -2.87   15.121  1 14.431 ? 509  ILE B CB  1 
ATOM   8106 C  CG1 . ILE B 1 517 ? 27.519  -2.623  16.554  1 16.415 ? 509  ILE B CG1 1 
ATOM   8107 C  CG2 . ILE B 1 517 ? 27.933  -2.51   14.015  1 16.344 ? 509  ILE B CG2 1 
ATOM   8108 C  CD1 . ILE B 1 517 ? 28.155  -1.25   16.71   1 18.301 ? 509  ILE B CD1 1 
ATOM   8109 N  N   . HIS B 1 518 ? 24.862  -3.742  13.261  1 14.938 ? 510  HIS B N   1 
ATOM   8110 C  CA  . HIS B 1 518 ? 24.051  -4.232  12.174  1 15.19  ? 510  HIS B CA  1 
ATOM   8111 C  C   . HIS B 1 518 ? 22.896  -5.098  12.676  1 17.125 ? 510  HIS B C   1 
ATOM   8112 O  O   . HIS B 1 518 ? 22.78   -5.512  13.833  1 17.428 ? 510  HIS B O   1 
ATOM   8113 C  CB  . HIS B 1 518 ? 24.917  -5      11.159  1 15.869 ? 510  HIS B CB  1 
ATOM   8114 C  CG  . HIS B 1 518 ? 26.006  -4.16   10.57   1 14.783 ? 510  HIS B CG  1 
ATOM   8115 N  ND1 . HIS B 1 518 ? 25.77   -3.224  9.592   1 16.677 ? 510  HIS B ND1 1 
ATOM   8116 C  CD2 . HIS B 1 518 ? 27.306  -4.082  10.833  1 15.825 ? 510  HIS B CD2 1 
ATOM   8117 C  CE1 . HIS B 1 518 ? 26.898  -2.631  9.245   1 15.331 ? 510  HIS B CE1 1 
ATOM   8118 N  NE2 . HIS B 1 518 ? 27.834  -3.069  10.007  1 15.157 ? 510  HIS B NE2 1 
ATOM   8119 N  N   . GLY B 1 519 ? 21.985  -5.327  11.747  1 13.8   ? 511  GLY B N   1 
ATOM   8120 C  CA  . GLY B 1 519 ? 20.843  -6.189  11.942  1 11.157 ? 511  GLY B CA  1 
ATOM   8121 C  C   . GLY B 1 519 ? 20.476  -6.757  10.587  1 13.613 ? 511  GLY B C   1 
ATOM   8122 O  O   . GLY B 1 519 ? 20.994  -6.223  9.624   1 13.719 ? 511  GLY B O   1 
ATOM   8123 N  N   . GLN B 1 520 ? 19.572  -7.743  10.567  1 12.435 ? 512  GLN B N   1 
ATOM   8124 C  CA  . GLN B 1 520 ? 19.267  -8.382  9.305   1 12.994 ? 512  GLN B CA  1 
ATOM   8125 C  C   . GLN B 1 520 ? 17.812  -8.764  9.365   1 13.568 ? 512  GLN B C   1 
ATOM   8126 O  O   . GLN B 1 520 ? 17.328  -9.152  10.458  1 14.005 ? 512  GLN B O   1 
ATOM   8127 C  CB  . GLN B 1 520 ? 20.137  -9.614  9.016   1 14.465 ? 512  GLN B CB  1 
ATOM   8128 C  CG  . GLN B 1 520 ? 21.629  -9.361  8.88    1 15.331 ? 512  GLN B CG  1 
ATOM   8129 C  CD  . GLN B 1 520 ? 22.047  -8.442  7.76    1 17.444 ? 512  GLN B CD  1 
ATOM   8130 O  OE1 . GLN B 1 520 ? 21.38   -8.326  6.716   1 19.078 ? 512  GLN B OE1 1 
ATOM   8131 N  NE2 . GLN B 1 520 ? 23.198  -7.825  7.979   1 14.406 ? 512  GLN B NE2 1 
ATOM   8132 N  N   . TRP B 1 521 ? 17.152  -8.654  8.183   1 11.019 ? 513  TRP B N   1 
ATOM   8133 C  CA  . TRP B 1 521 ? 15.863  -9.304  8.03    1 13.247 ? 513  TRP B CA  1 
ATOM   8134 C  C   . TRP B 1 521 ? 16.147  -10.738 7.581   1 13.778 ? 513  TRP B C   1 
ATOM   8135 O  O   . TRP B 1 521 ? 16.654  -10.969 6.497   1 17.789 ? 513  TRP B O   1 
ATOM   8136 C  CB  . TRP B 1 521 ? 14.93   -8.566  7.035   1 14.817 ? 513  TRP B CB  1 
ATOM   8137 C  CG  . TRP B 1 521 ? 13.631  -9.299  6.879   1 16.162 ? 513  TRP B CG  1 
ATOM   8138 C  CD1 . TRP B 1 521 ? 13.254  -10.103 5.827   1 16.596 ? 513  TRP B CD1 1 
ATOM   8139 C  CD2 . TRP B 1 521 ? 12.593  -9.418  7.87    1 18.653 ? 513  TRP B CD2 1 
ATOM   8140 N  NE1 . TRP B 1 521 ? 12.034  -10.689 6.057   1 16.555 ? 513  TRP B NE1 1 
ATOM   8141 C  CE2 . TRP B 1 521 ? 11.599  -10.273 7.308   1 18.398 ? 513  TRP B CE2 1 
ATOM   8142 C  CE3 . TRP B 1 521 ? 12.382  -8.867  9.151   1 17.855 ? 513  TRP B CE3 1 
ATOM   8143 C  CZ2 . TRP B 1 521 ? 10.435  -10.599 7.992   1 16.171 ? 513  TRP B CZ2 1 
ATOM   8144 C  CZ3 . TRP B 1 521 ? 11.227  -9.209  9.834   1 17.564 ? 513  TRP B CZ3 1 
ATOM   8145 C  CH2 . TRP B 1 521 ? 10.258  -10.061 9.261   1 17.979 ? 513  TRP B CH2 1 
ATOM   8146 N  N   . ILE B 1 522 ? 15.775  -11.698 8.405   1 12.529 ? 514  ILE B N   1 
ATOM   8147 C  CA  . ILE B 1 522 ? 15.968  -13.107 8.089   1 14.315 ? 514  ILE B CA  1 
ATOM   8148 C  C   . ILE B 1 522 ? 14.575  -13.727 7.828   1 14.245 ? 514  ILE B C   1 
ATOM   8149 O  O   . ILE B 1 522 ? 13.801  -14.024 8.733   1 13.754 ? 514  ILE B O   1 
ATOM   8150 C  CB  . ILE B 1 522 ? 16.724  -13.812 9.227   1 13.829 ? 514  ILE B CB  1 
ATOM   8151 C  CG1 . ILE B 1 522 ? 18.125  -13.143 9.546   1 14.632 ? 514  ILE B CG1 1 
ATOM   8152 C  CG2 . ILE B 1 522 ? 16.779  -15.34  9.026   1 15.623 ? 514  ILE B CG2 1 
ATOM   8153 C  CD1 . ILE B 1 522 ? 19.103  -13.087 8.404   1 17.427 ? 514  ILE B CD1 1 
ATOM   8154 N  N   . PRO B 1 523 ? 14.231  -14.039 6.55    1 13.625 ? 515  PRO B N   1 
ATOM   8155 C  CA  . PRO B 1 523 ? 12.943  -14.599 6.24    1 15.132 ? 515  PRO B CA  1 
ATOM   8156 C  C   . PRO B 1 523 ? 12.649  -15.894 6.971   1 15.565 ? 515  PRO B C   1 
ATOM   8157 O  O   . PRO B 1 523 ? 13.534  -16.712 7.192   1 18.104 ? 515  PRO B O   1 
ATOM   8158 C  CB  . PRO B 1 523 ? 13.052  -14.936 4.719   1 14.818 ? 515  PRO B CB  1 
ATOM   8159 C  CG  . PRO B 1 523 ? 14.08   -13.999 4.226   1 14.259 ? 515  PRO B CG  1 
ATOM   8160 C  CD  . PRO B 1 523 ? 15.054  -13.815 5.34    1 15.914 ? 515  PRO B CD  1 
ATOM   8161 N  N   . GLY B 1 524 ? 11.363  -16.106 7.288   1 15.978 ? 516  GLY B N   1 
ATOM   8162 C  CA  . GLY B 1 524 ? 10.981  -17.338 7.941   1 18.454 ? 516  GLY B CA  1 
ATOM   8163 C  C   . GLY B 1 524 ? 11.382  -18.58  7.162   1 18.494 ? 516  GLY B C   1 
ATOM   8164 O  O   . GLY B 1 524 ? 11.678  -19.61  7.779   1 17.614 ? 516  GLY B O   1 
ATOM   8165 N  N   . GLU B 1 525 ? 11.321  -18.465 5.813   1 15.772 ? 517  GLU B N   1 
ATOM   8166 C  CA  . GLU B 1 525 ? 11.572  -19.554 4.865   1 21.868 ? 517  GLU B CA  1 
ATOM   8167 C  C   . GLU B 1 525 ? 13.004  -20.122 4.952   1 22.483 ? 517  GLU B C   1 
ATOM   8168 O  O   . GLU B 1 525 ? 13.232  -21.299 4.608   1 23.564 ? 517  GLU B O   1 
ATOM   8169 C  CB  . GLU B 1 525 ? 11.106  -18.946 3.533   1 22.597 ? 517  GLU B CB  1 
ATOM   8170 C  CG  . GLU B 1 525 ? 11.555  -19.666 2.268   1 32.753 ? 517  GLU B CG  1 
ATOM   8171 C  CD  . GLU B 1 525 ? 11.15   -18.995 0.951   1 35.71  ? 517  GLU B CD  1 
ATOM   8172 O  OE1 . GLU B 1 525 ? 10.78   -17.807 1.076   1 40.5   ? 517  GLU B OE1 1 
ATOM   8173 O  OE2 . GLU B 1 525 ? 11.192  -19.621 -0.181  1 33.766 ? 517  GLU B OE2 1 
ATOM   8174 N  N   . VAL B 1 526 ? 13.968  -19.297 5.421   1 19.3   ? 518  VAL B N   1 
ATOM   8175 C  CA  . VAL B 1 526 ? 15.357  -19.69  5.513   1 19.24  ? 518  VAL B CA  1 
ATOM   8176 C  C   . VAL B 1 526 ? 15.711  -20.017 6.963   1 18.814 ? 518  VAL B C   1 
ATOM   8177 O  O   . VAL B 1 526 ? 16.89   -20.313 7.225   1 20.707 ? 518  VAL B O   1 
ATOM   8178 C  CB  . VAL B 1 526 ? 16.294  -18.646 4.848   1 22.842 ? 518  VAL B CB  1 
ATOM   8179 C  CG1 . VAL B 1 526 ? 15.985  -18.436 3.353   1 19.145 ? 518  VAL B CG1 1 
ATOM   8180 C  CG2 . VAL B 1 526 ? 16.392  -17.312 5.596   1 18.98  ? 518  VAL B CG2 1 
ATOM   8181 N  N   . THR B 1 527 ? 14.704  -19.967 7.845   1 17.676 ? 519  THR B N   1 
ATOM   8182 C  CA  . THR B 1 527 ? 14.933  -20.238 9.264   1 16.146 ? 519  THR B CA  1 
ATOM   8183 C  C   . THR B 1 527 ? 14.512  -21.676 9.579   1 19.335 ? 519  THR B C   1 
ATOM   8184 O  O   . THR B 1 527 ? 13.302  -21.938 9.503   1 18.56  ? 519  THR B O   1 
ATOM   8185 C  CB  . THR B 1 527 ? 14.153  -19.243 10.119  1 18.008 ? 519  THR B CB  1 
ATOM   8186 O  OG1 . THR B 1 527 ? 14.517  -17.953 9.632   1 19.395 ? 519  THR B OG1 1 
ATOM   8187 C  CG2 . THR B 1 527 ? 14.521  -19.399 11.593  1 14.389 ? 519  THR B CG2 1 
ATOM   8188 N  N   . PRO B 1 528 ? 15.414  -22.6   10.025  1 20.727 ? 520  PRO B N   1 
ATOM   8189 C  CA  . PRO B 1 528 ? 14.97   -23.93  10.46   1 21.253 ? 520  PRO B CA  1 
ATOM   8190 C  C   . PRO B 1 528 ? 13.818  -23.86  11.466  1 20.608 ? 520  PRO B C   1 
ATOM   8191 O  O   . PRO B 1 528 ? 13.889  -23.031 12.376  1 23.243 ? 520  PRO B O   1 
ATOM   8192 C  CB  . PRO B 1 528 ? 16.226  -24.632 10.968  1 22.754 ? 520  PRO B CB  1 
ATOM   8193 C  CG  . PRO B 1 528 ? 17.383  -23.856 10.352  1 20.568 ? 520  PRO B CG  1 
ATOM   8194 C  CD  . PRO B 1 528 ? 16.869  -22.431 10.167  1 19.989 ? 520  PRO B CD  1 
ATOM   8195 N  N   . ASP B 1 529 ? 12.72   -24.617 11.217  1 18.713 ? 521  ASP B N   1 
ATOM   8196 C  CA  . ASP B 1 529 ? 11.62   -24.835 12.139  1 22.155 ? 521  ASP B CA  1 
ATOM   8197 C  C   . ASP B 1 529 ? 10.875  -23.546 12.484  1 21.76  ? 521  ASP B C   1 
ATOM   8198 O  O   . ASP B 1 529 ? 10.381  -23.441 13.628  1 22.479 ? 521  ASP B O   1 
ATOM   8199 C  CB  . ASP B 1 529 ? 12.107  -25.418 13.467  1 19.937 ? 521  ASP B CB  1 
ATOM   8200 C  CG  . ASP B 1 529 ? 12.857  -26.732 13.282  1 26.084 ? 521  ASP B CG  1 
ATOM   8201 O  OD1 . ASP B 1 529 ? 12.236  -27.611 12.724  1 24.834 ? 521  ASP B OD1 1 
ATOM   8202 O  OD2 . ASP B 1 529 ? 14.073  -26.807 13.585  1 22.592 ? 521  ASP B OD2 1 
ATOM   8203 N  N   . PHE B 1 530 ? 10.866  -22.57  11.561  1 16.872 ? 522  PHE B N   1 
ATOM   8204 C  CA  . PHE B 1 530 ? 10.204  -21.283 11.803  1 17.778 ? 522  PHE B CA  1 
ATOM   8205 C  C   . PHE B 1 530 ? 8.692   -21.524 11.957  1 19.987 ? 522  PHE B C   1 
ATOM   8206 O  O   . PHE B 1 530 ? 8.012   -20.801 12.703  1 19.861 ? 522  PHE B O   1 
ATOM   8207 C  CB  . PHE B 1 530 ? 10.434  -20.289 10.672  1 18.065 ? 522  PHE B CB  1 
ATOM   8208 C  CG  . PHE B 1 530 ? 9.818   -18.905 10.861  1 16.534 ? 522  PHE B CG  1 
ATOM   8209 C  CD1 . PHE B 1 530 ? 10.545  -17.891 11.504  1 14.481 ? 522  PHE B CD1 1 
ATOM   8210 C  CD2 . PHE B 1 530 ? 8.542   -18.604 10.348  1 16.523 ? 522  PHE B CD2 1 
ATOM   8211 C  CE1 . PHE B 1 530 ? 9.991   -16.593 11.659  1 14.524 ? 522  PHE B CE1 1 
ATOM   8212 C  CE2 . PHE B 1 530 ? 7.967   -17.337 10.559  1 19.929 ? 522  PHE B CE2 1 
ATOM   8213 C  CZ  . PHE B 1 530 ? 8.681   -16.334 11.245  1 16.612 ? 522  PHE B CZ  1 
ATOM   8214 N  N   . GLU B 1 531 ? 8.177   -22.556 11.245  1 20.365 ? 523  GLU B N   1 
ATOM   8215 C  CA  . GLU B 1 531 ? 6.735   -22.869 11.275  1 24.378 ? 523  GLU B CA  1 
ATOM   8216 C  C   . GLU B 1 531 ? 6.219   -23.414 12.609  1 21.95  ? 523  GLU B C   1 
ATOM   8217 O  O   . GLU B 1 531 ? 5.018   -23.327 12.886  1 28.983 ? 523  GLU B O   1 
ATOM   8218 C  CB  . GLU B 1 531 ? 6.237   -23.65  10.06   1 21.601 ? 523  GLU B CB  1 
ATOM   8219 C  CG  . GLU B 1 531 ? 6.361   -22.845 8.77    1 22.282 ? 523  GLU B CG  1 
ATOM   8220 C  CD  . GLU B 1 531 ? 5.804   -21.43  8.711   1 29.029 ? 523  GLU B CD  1 
ATOM   8221 O  OE1 . GLU B 1 531 ? 4.708   -21.184 9.257   1 41.842 ? 523  GLU B OE1 1 
ATOM   8222 O  OE2 . GLU B 1 531 ? 6.445   -20.565 8.091   1 25.342 ? 523  GLU B OE2 1 
ATOM   8223 N  N   . THR B 1 532 ? 7.119   -23.918 13.432  1 19.239 ? 524  THR B N   1 
ATOM   8224 C  CA  . THR B 1 532 ? 6.778   -24.653 14.648  1 19.516 ? 524  THR B CA  1 
ATOM   8225 C  C   . THR B 1 532 ? 7.369   -24.075 15.922  1 22.884 ? 524  THR B C   1 
ATOM   8226 O  O   . THR B 1 532 ? 6.926   -24.459 17.004  1 19.792 ? 524  THR B O   1 
ATOM   8227 C  CB  . THR B 1 532 ? 7.107   -26.144 14.493  1 21.286 ? 524  THR B CB  1 
ATOM   8228 O  OG1 . THR B 1 532 ? 8.52    -26.342 14.39   1 23.419 ? 524  THR B OG1 1 
ATOM   8229 C  CG2 . THR B 1 532 ? 6.272   -26.85  13.419  1 27.015 ? 524  THR B CG2 1 
ATOM   8230 N  N   . LYS B 1 533 ? 8.385   -23.193 15.811  1 23.452 ? 525  LYS B N   1 
ATOM   8231 C  CA  . LYS B 1 533 ? 9.105   -22.729 16.989  1 23.451 ? 525  LYS B CA  1 
ATOM   8232 C  C   . LYS B 1 533 ? 9.039   -21.216 17.007  1 21.388 ? 525  LYS B C   1 
ATOM   8233 O  O   . LYS B 1 533 ? 9.301   -20.594 15.993  1 24.316 ? 525  LYS B O   1 
ATOM   8234 C  CB  . LYS B 1 533 ? 10.579  -23.189 17.017  1 22.581 ? 525  LYS B CB  1 
ATOM   8235 C  CG  . LYS B 1 533 ? 10.681  -24.631 17.473  1 25.33  ? 525  LYS B CG  1 
ATOM   8236 C  CD  . LYS B 1 533 ? 12.115  -25.061 17.19   1 30.262 ? 525  LYS B CD  1 
ATOM   8237 C  CE  . LYS B 1 533 ? 12.283  -26.543 17.168  1 36.626 ? 525  LYS B CE  1 
ATOM   8238 N  NZ  . LYS B 1 533 ? 13.635  -26.87  16.73   1 38.518 ? 525  LYS B NZ  1 
ATOM   8239 N  N   . GLY B 1 534 ? 8.62    -20.674 18.155  1 25.988 ? 526  GLY B N   1 
ATOM   8240 C  CA  . GLY B 1 534 ? 8.583   -19.235 18.342  1 18.804 ? 526  GLY B CA  1 
ATOM   8241 C  C   . GLY B 1 534 ? 9.809   -18.853 19.173  1 18.799 ? 526  GLY B C   1 
ATOM   8242 O  O   . GLY B 1 534 ? 10.533  -19.747 19.593  1 18.865 ? 526  GLY B O   1 
ATOM   8243 N  N   . LEU B 1 535 ? 10.027  -17.544 19.369  1 14.89  ? 527  LEU B N   1 
ATOM   8244 C  CA  . LEU B 1 535 ? 11.087  -17.055 20.249  1 16.734 ? 527  LEU B CA  1 
ATOM   8245 C  C   . LEU B 1 535 ? 10.796  -17.42  21.711  1 15.763 ? 527  LEU B C   1 
ATOM   8246 O  O   . LEU B 1 535 ? 11.731  -17.589 22.497  1 17.643 ? 527  LEU B O   1 
ATOM   8247 C  CB  . LEU B 1 535 ? 11.195  -15.546 20.087  1 15.444 ? 527  LEU B CB  1 
ATOM   8248 C  CG  . LEU B 1 535 ? 11.671  -15.035 18.713  1 17.222 ? 527  LEU B CG  1 
ATOM   8249 C  CD1 . LEU B 1 535 ? 11.814  -13.512 18.845  1 14.305 ? 527  LEU B CD1 1 
ATOM   8250 C  CD2 . LEU B 1 535 ? 13.012  -15.629 18.313  1 16.914 ? 527  LEU B CD2 1 
ATOM   8251 N  N   . VAL B 1 536 ? 9.505   -17.632 22.027  1 15.846 ? 528  VAL B N   1 
ATOM   8252 C  CA  . VAL B 1 536 ? 9.103   -17.939 23.395  1 15.022 ? 528  VAL B CA  1 
ATOM   8253 C  C   . VAL B 1 536 ? 8.397   -19.299 23.366  1 17.882 ? 528  VAL B C   1 
ATOM   8254 O  O   . VAL B 1 536 ? 7.458   -19.49  22.598  1 19.487 ? 528  VAL B O   1 
ATOM   8255 C  CB  . VAL B 1 536 ? 8.183   -16.841 23.982  1 17.728 ? 528  VAL B CB  1 
ATOM   8256 C  CG1 . VAL B 1 536 ? 7.936   -17.077 25.494  1 20.909 ? 528  VAL B CG1 1 
ATOM   8257 C  CG2 . VAL B 1 536 ? 8.72    -15.429 23.751  1 17.379 ? 528  VAL B CG2 1 
ATOM   8258 N  N   . ASP B 1 537 ? 8.785   -20.242 24.217  1 17.309 ? 529  ASP B N   1 
ATOM   8259 C  CA  . ASP B 1 537 ? 8.047   -21.509 24.222  1 22.477 ? 529  ASP B CA  1 
ATOM   8260 C  C   . ASP B 1 537 ? 6.733   -21.339 24.963  1 23.285 ? 529  ASP B C   1 
ATOM   8261 O  O   . ASP B 1 537 ? 6.709   -20.71  26.018  1 19.862 ? 529  ASP B O   1 
ATOM   8262 C  CB  . ASP B 1 537 ? 8.853   -22.676 24.754  1 24.106 ? 529  ASP B CB  1 
ATOM   8263 C  CG  . ASP B 1 537 ? 9.857   -23.311 23.799  1 31.398 ? 529  ASP B CG  1 
ATOM   8264 O  OD1 . ASP B 1 537 ? 9.675   -23.216 22.538  1 25.371 ? 529  ASP B OD1 1 
ATOM   8265 O  OD2 . ASP B 1 537 ? 10.845  -23.866 24.337  1 32.302 ? 529  ASP B OD2 1 
ATOM   8266 N  N   . LEU B 1 538 ? 5.64    -21.896 24.412  1 20.949 ? 530  LEU B N   1 
ATOM   8267 C  CA  . LEU B 1 538 ? 4.34    -21.748 25.054  1 20.848 ? 530  LEU B CA  1 
ATOM   8268 C  C   . LEU B 1 538 ? 4.36    -22.571 26.339  1 19.375 ? 530  LEU B C   1 
ATOM   8269 O  O   . LEU B 1 538 ? 5.037   -23.607 26.399  1 20.426 ? 530  LEU B O   1 
ATOM   8270 C  CB  . LEU B 1 538 ? 3.185   -22.126 24.134  1 21.648 ? 530  LEU B CB  1 
ATOM   8271 C  CG  . LEU B 1 538 ? 3.081   -21.347 22.816  1 23.914 ? 530  LEU B CG  1 
ATOM   8272 C  CD1 . LEU B 1 538 ? 1.911   -21.923 22.003  1 28.216 ? 530  LEU B CD1 1 
ATOM   8273 C  CD2 . LEU B 1 538 ? 2.903   -19.83  23.079  1 27.455 ? 530  LEU B CD2 1 
ATOM   8274 N  N   . PRO B 1 539 ? 3.598   -22.212 27.389  1 18.857 ? 531  PRO B N   1 
ATOM   8275 C  CA  . PRO B 1 539 ? 3.381   -23.144 28.496  1 21.153 ? 531  PRO B CA  1 
ATOM   8276 C  C   . PRO B 1 539 ? 2.565   -24.37  28.074  1 18.756 ? 531  PRO B C   1 
ATOM   8277 O  O   . PRO B 1 539 ? 2       -24.401 26.972  1 16.88  ? 531  PRO B O   1 
ATOM   8278 C  CB  . PRO B 1 539 ? 2.815   -22.253 29.622  1 21.45  ? 531  PRO B CB  1 
ATOM   8279 C  CG  . PRO B 1 539 ? 2.054   -21.226 28.798  1 22.413 ? 531  PRO B CG  1 
ATOM   8280 C  CD  . PRO B 1 539 ? 2.894   -20.928 27.579  1 19.978 ? 531  PRO B CD  1 
ATOM   8281 N  N   . LYS B 1 540 ? 2.517   -25.38  28.963  1 18.735 ? 532  LYS B N   1 
ATOM   8282 C  CA  . LYS B 1 540 ? 1.852   -26.641 28.643  1 18.873 ? 532  LYS B CA  1 
ATOM   8283 C  C   . LYS B 1 540 ? 0.336   -26.396 28.598  1 20.494 ? 532  LYS B C   1 
ATOM   8284 O  O   . LYS B 1 540 ? -0.178  -25.437 29.201  1 19.773 ? 532  LYS B O   1 
ATOM   8285 C  CB  . LYS B 1 540 ? 2.17    -27.733 29.673  1 16.061 ? 532  LYS B CB  1 
ATOM   8286 C  CG  . LYS B 1 540 ? 1.712   -27.458 31.126  1 16.116 ? 532  LYS B CG  1 
ATOM   8287 C  CD  . LYS B 1 540 ? 1.924   -28.757 31.904  1 18.736 ? 532  LYS B CD  1 
ATOM   8288 C  CE  . LYS B 1 540 ? 1.554   -28.571 33.328  1 20.327 ? 532  LYS B CE  1 
ATOM   8289 N  NZ  . LYS B 1 540 ? 1.605   -29.874 34.045  1 18.496 ? 532  LYS B NZ  1 
ATOM   8290 N  N   . GLU B 1 541 ? -0.373  -27.228 27.832  1 18.677 ? 533  GLU B N   1 
ATOM   8291 C  CA  . GLU B 1 541 ? -1.83   -27.125 27.768  1 16.336 ? 533  GLU B CA  1 
ATOM   8292 C  C   . GLU B 1 541 ? -2.497  -27.583 29.071  1 16.476 ? 533  GLU B C   1 
ATOM   8293 O  O   . GLU B 1 541 ? -3.475  -26.962 29.53   1 23.517 ? 533  GLU B O   1 
ATOM   8294 C  CB  . GLU B 1 541 ? -2.348  -28.013 26.632  1 18.94  ? 533  GLU B CB  1 
ATOM   8295 C  CG  . GLU B 1 541 ? -3.783  -27.616 26.299  1 23.437 ? 533  GLU B CG  1 
ATOM   8296 C  CD  . GLU B 1 541 ? -4.349  -28.481 25.187  1 33.228 ? 533  GLU B CD  1 
ATOM   8297 O  OE1 . GLU B 1 541 ? -3.674  -29.465 24.768  1 34.916 ? 533  GLU B OE1 1 
ATOM   8298 O  OE2 . GLU B 1 541 ? -5.475  -28.157 24.757  1 33.729 ? 533  GLU B OE2 1 
ATOM   8299 N  N   . GLU B 1 542 ? -2.126  -28.76  29.561  1 17.102 ? 534  GLU B N   1 
ATOM   8300 C  CA  . GLU B 1 542 ? -2.777  -29.363 30.732  1 17.931 ? 534  GLU B CA  1 
ATOM   8301 C  C   . GLU B 1 542 ? -2.832  -28.387 31.92   1 16.465 ? 534  GLU B C   1 
ATOM   8302 O  O   . GLU B 1 542 ? -1.885  -27.64  32.126  1 15.617 ? 534  GLU B O   1 
ATOM   8303 C  CB  . GLU B 1 542 ? -1.918  -30.496 31.257  1 20.921 ? 534  GLU B CB  1 
ATOM   8304 C  CG  . GLU B 1 542 ? -2.705  -31.512 32.087  1 26.329 ? 534  GLU B CG  1 
ATOM   8305 C  CD  . GLU B 1 542 ? -1.94   -32.84  32.083  1 34.225 ? 534  GLU B CD  1 
ATOM   8306 O  OE1 . GLU B 1 542 ? -1.662  -33.371 30.977  1 37.349 ? 534  GLU B OE1 1 
ATOM   8307 O  OE2 . GLU B 1 542 ? -1.552  -33.286 33.179  1 32.729 ? 534  GLU B OE2 1 
ATOM   8308 N  N   . HIS B 1 543 ? -3.986  -28.295 32.575  1 18.171 ? 535  HIS B N   1 
ATOM   8309 C  CA  . HIS B 1 543 ? -4.181  -27.493 33.793  1 18.907 ? 535  HIS B CA  1 
ATOM   8310 C  C   . HIS B 1 543 ? -3.327  -28.055 34.924  1 17.954 ? 535  HIS B C   1 
ATOM   8311 O  O   . HIS B 1 543 ? -3.277  -29.261 35.125  1 18.063 ? 535  HIS B O   1 
ATOM   8312 C  CB  . HIS B 1 543 ? -5.668  -27.423 34.167  1 18.899 ? 535  HIS B CB  1 
ATOM   8313 C  CG  . HIS B 1 543 ? -6.478  -26.663 33.179  1 18.861 ? 535  HIS B CG  1 
ATOM   8314 N  ND1 . HIS B 1 543 ? -7.781  -26.954 32.855  1 19.182 ? 535  HIS B ND1 1 
ATOM   8315 C  CD2 . HIS B 1 543 ? -6.143  -25.549 32.479  1 15.63  ? 535  HIS B CD2 1 
ATOM   8316 C  CE1 . HIS B 1 543 ? -8.23   -26.03  31.978  1 17.798 ? 535  HIS B CE1 1 
ATOM   8317 N  NE2 . HIS B 1 543 ? -7.246  -25.191 31.729  1 24.824 ? 535  HIS B NE2 1 
ATOM   8318 N  N   . TRP B 1 544 ? -2.648  -27.168 35.662  1 18.436 ? 536  TRP B N   1 
ATOM   8319 C  CA  . TRP B 1 544 ? -2.114  -27.576 36.956  1 17.264 ? 536  TRP B CA  1 
ATOM   8320 C  C   . TRP B 1 544 ? -3.208  -28.025 37.919  1 16.078 ? 536  TRP B C   1 
ATOM   8321 O  O   . TRP B 1 544 ? -3.016  -28.961 38.706  1 15.665 ? 536  TRP B O   1 
ATOM   8322 C  CB  . TRP B 1 544 ? -1.27   -26.492 37.644  1 18.879 ? 536  TRP B CB  1 
ATOM   8323 C  CG  . TRP B 1 544 ? -0.099  -25.941 36.886  1 16.5   ? 536  TRP B CG  1 
ATOM   8324 C  CD1 . TRP B 1 544 ? -0.027  -24.697 36.303  1 15.557 ? 536  TRP B CD1 1 
ATOM   8325 C  CD2 . TRP B 1 544 ? 1.183   -26.587 36.664  1 14.038 ? 536  TRP B CD2 1 
ATOM   8326 N  NE1 . TRP B 1 544 ? 1.228   -24.531 35.768  1 15.523 ? 536  TRP B NE1 1 
ATOM   8327 C  CE2 . TRP B 1 544 ? 1.978   -25.666 35.931  1 15.705 ? 536  TRP B CE2 1 
ATOM   8328 C  CE3 . TRP B 1 544 ? 1.721   -27.849 36.975  1 15.492 ? 536  TRP B CE3 1 
ATOM   8329 C  CZ2 . TRP B 1 544 ? 3.295   -25.952 35.534  1 16.035 ? 536  TRP B CZ2 1 
ATOM   8330 C  CZ3 . TRP B 1 544 ? 3.022   -28.141 36.579  1 19.947 ? 536  TRP B CZ3 1 
ATOM   8331 C  CH2 . TRP B 1 544 ? 3.82    -27.189 35.876  1 16.315 ? 536  TRP B CH2 1 
ATOM   8332 N  N   . ALA B 1 545 ? -4.317  -27.292 37.956  1 17.007 ? 537  ALA B N   1 
ATOM   8333 C  CA  . ALA B 1 545 ? -5.219  -27.48  39.069  1 16.001 ? 537  ALA B CA  1 
ATOM   8334 C  C   . ALA B 1 545 ? -6.313  -28.505 38.718  1 15.474 ? 537  ALA B C   1 
ATOM   8335 O  O   . ALA B 1 545 ? -6.757  -28.609 37.554  1 16.583 ? 537  ALA B O   1 
ATOM   8336 C  CB  . ALA B 1 545 ? -5.84   -26.128 39.387  1 13.117 ? 537  ALA B CB  1 
ATOM   8337 N  N   . PRO B 1 546 ? -6.863  -29.239 39.707  1 15.564 ? 538  PRO B N   1 
ATOM   8338 C  CA  . PRO B 1 546 ? -8.01   -30.106 39.414  1 17.704 ? 538  PRO B CA  1 
ATOM   8339 C  C   . PRO B 1 546 ? -9.315  -29.292 39.231  1 21.276 ? 538  PRO B C   1 
ATOM   8340 O  O   . PRO B 1 546 ? -9.423  -28.177 39.73   1 18.752 ? 538  PRO B O   1 
ATOM   8341 C  CB  . PRO B 1 546 ? -8.001  -31.038 40.618  1 21.34  ? 538  PRO B CB  1 
ATOM   8342 C  CG  . PRO B 1 546 ? -7.5    -30.174 41.726  1 14.389 ? 538  PRO B CG  1 
ATOM   8343 C  CD  . PRO B 1 546 ? -6.501  -29.226 41.137  1 15.626 ? 538  PRO B CD  1 
ATOM   8344 N  N   . LEU B 1 547 ? -10.308 -29.816 38.478  1 16.695 ? 539  LEU B N   1 
ATOM   8345 C  CA  . LEU B 1 547 ? -11.637 -29.221 38.374  1 18.235 ? 539  LEU B CA  1 
ATOM   8346 C  C   . LEU B 1 547 ? -12.262 -28.83  39.715  1 18.836 ? 539  LEU B C   1 
ATOM   8347 O  O   . LEU B 1 547 ? -12.895 -27.785 39.79   1 22.476 ? 539  LEU B O   1 
ATOM   8348 C  CB  . LEU B 1 547 ? -12.492 -30.239 37.619  1 22.797 ? 539  LEU B CB  1 
ATOM   8349 C  CG  . LEU B 1 547 ? -13.873 -29.765 37.16   1 27.957 ? 539  LEU B CG  1 
ATOM   8350 C  CD1 . LEU B 1 547 ? -13.789 -28.86  35.924  1 30.647 ? 539  LEU B CD1 1 
ATOM   8351 C  CD2 . LEU B 1 547 ? -14.654 -31.042 36.845  1 30.458 ? 539  LEU B CD2 1 
ATOM   8352 N  N   . SER B 1 548 ? -12.047 -29.635 40.76   1 19.625 ? 540  SER B N   1 
ATOM   8353 C  CA  . SER B 1 548 ? -12.652 -29.446 42.078  1 21.353 ? 540  SER B CA  1 
ATOM   8354 C  C   . SER B 1 548 ? -12.196 -28.157 42.78   1 22.456 ? 540  SER B C   1 
ATOM   8355 O  O   . SER B 1 548 ? -12.716 -27.783 43.855  1 21.859 ? 540  SER B O   1 
ATOM   8356 C  CB  . SER B 1 548 ? -12.381 -30.675 42.943  1 20.679 ? 540  SER B CB  1 
ATOM   8357 O  OG  . SER B 1 548 ? -10.996 -30.878 43.18   1 29.459 ? 540  SER B OG  1 
ATOM   8358 N  N   . GLN B 1 549 ? -11.124 -27.542 42.284  1 17.689 ? 541  GLN B N   1 
ATOM   8359 C  CA  . GLN B 1 549 ? -10.572 -26.313 42.862  1 15.634 ? 541  GLN B CA  1 
ATOM   8360 C  C   . GLN B 1 549 ? -11.189 -25.03  42.271  1 18.451 ? 541  GLN B C   1 
ATOM   8361 O  O   . GLN B 1 549 ? -10.912 -23.963 42.837  1 18.143 ? 541  GLN B O   1 
ATOM   8362 C  CB  . GLN B 1 549 ? -9.046  -26.285 42.759  1 12.227 ? 541  GLN B CB  1 
ATOM   8363 C  CG  . GLN B 1 549 ? -8.425  -27.233 43.759  1 12.721 ? 541  GLN B CG  1 
ATOM   8364 C  CD  . GLN B 1 549 ? -8.287  -26.596 45.131  1 13.057 ? 541  GLN B CD  1 
ATOM   8365 O  OE1 . GLN B 1 549 ? -7.686  -25.536 45.27   1 13.933 ? 541  GLN B OE1 1 
ATOM   8366 N  NE2 . GLN B 1 549 ? -8.767  -27.234 46.184  1 14.94  ? 541  GLN B NE2 1 
ATOM   8367 N  N   . SER B 1 550 ? -12.049 -25.142 41.228  1 18.04  ? 542  SER B N   1 
ATOM   8368 C  CA  . SER B 1 550 ? -12.673 -23.953 40.648  1 19.514 ? 542  SER B CA  1 
ATOM   8369 C  C   . SER B 1 550 ? -13.6   -23.29  41.658  1 15.633 ? 542  SER B C   1 
ATOM   8370 O  O   . SER B 1 550 ? -14.306 -24.006 42.385  1 15.148 ? 542  SER B O   1 
ATOM   8371 C  CB  . SER B 1 550 ? -13.468 -24.188 39.389  1 19.616 ? 542  SER B CB  1 
ATOM   8372 O  OG  . SER B 1 550 ? -13.857 -22.903 38.908  1 21.34  ? 542  SER B OG  1 
ATOM   8373 N  N   . PRO B 1 551 ? -13.539 -21.94  41.85   1 17.453 ? 543  PRO B N   1 
ATOM   8374 C  CA  . PRO B 1 551 ? -14.531 -21.268 42.699  1 15.332 ? 543  PRO B CA  1 
ATOM   8375 C  C   . PRO B 1 551 ? -15.95  -21.433 42.182  1 17.095 ? 543  PRO B C   1 
ATOM   8376 O  O   . PRO B 1 551 ? -16.874 -21.347 42.972  1 15.516 ? 543  PRO B O   1 
ATOM   8377 C  CB  . PRO B 1 551 ? -14.077 -19.825 42.748  1 16.246 ? 543  PRO B CB  1 
ATOM   8378 C  CG  . PRO B 1 551 ? -13.381 -19.676 41.407  1 15.597 ? 543  PRO B CG  1 
ATOM   8379 C  CD  . PRO B 1 551 ? -12.579 -20.978 41.266  1 15.688 ? 543  PRO B CD  1 
ATOM   8380 N  N   . TYR B 1 552 ? -16.092 -21.603 40.835  1 15.792 ? 544  TYR B N   1 
ATOM   8381 C  CA  . TYR B 1 552 ? -17.373 -21.593 40.142  1 14.576 ? 544  TYR B CA  1 
ATOM   8382 C  C   . TYR B 1 552 ? -17.953 -22.995 40.174  1 16.542 ? 544  TYR B C   1 
ATOM   8383 O  O   . TYR B 1 552 ? -17.197 -23.974 40.013  1 18.769 ? 544  TYR B O   1 
ATOM   8384 C  CB  . TYR B 1 552 ? -17.116 -21.186 38.691  1 13.625 ? 544  TYR B CB  1 
ATOM   8385 C  CG  . TYR B 1 552 ? -18.227 -21.5   37.717  1 16.891 ? 544  TYR B CG  1 
ATOM   8386 C  CD1 . TYR B 1 552 ? -19.404 -20.718 37.679  1 18.258 ? 544  TYR B CD1 1 
ATOM   8387 C  CD2 . TYR B 1 552 ? -18.131 -22.599 36.859  1 18.882 ? 544  TYR B CD2 1 
ATOM   8388 C  CE1 . TYR B 1 552 ? -20.399 -20.978 36.744  1 18.063 ? 544  TYR B CE1 1 
ATOM   8389 C  CE2 . TYR B 1 552 ? -19.151 -22.898 35.967  1 20.825 ? 544  TYR B CE2 1 
ATOM   8390 C  CZ  . TYR B 1 552 ? -20.277 -22.078 35.908  1 20.227 ? 544  TYR B CZ  1 
ATOM   8391 O  OH  . TYR B 1 552 ? -21.28  -22.315 35.008  1 20.273 ? 544  TYR B OH  1 
ATOM   8392 N  N   . ASP B 1 553 ? -19.248 -23.035 40.498  1 15.429 ? 545  ASP B N   1 
ATOM   8393 C  CA  . ASP B 1 553 ? -20.062 -24.246 40.454  1 19.644 ? 545  ASP B CA  1 
ATOM   8394 C  C   . ASP B 1 553 ? -21.203 -24.045 39.461  1 16.893 ? 545  ASP B C   1 
ATOM   8395 O  O   . ASP B 1 553 ? -22.097 -23.249 39.706  1 16.017 ? 545  ASP B O   1 
ATOM   8396 C  CB  . ASP B 1 553 ? -20.496 -24.674 41.85   1 19.82  ? 545  ASP B CB  1 
ATOM   8397 C  CG  . ASP B 1 553 ? -21.352 -25.937 41.928  1 20.749 ? 545  ASP B CG  1 
ATOM   8398 O  OD1 . ASP B 1 553 ? -21.661 -26.517 40.881  1 20.524 ? 545  ASP B OD1 1 
ATOM   8399 O  OD2 . ASP B 1 553 ? -21.64  -26.36  43.039  1 25.428 ? 545  ASP B OD2 1 
ATOM   8400 N  N   . PRO B 1 554 ? -21.22  -24.762 38.315  1 18.976 ? 546  PRO B N   1 
ATOM   8401 C  CA  . PRO B 1 554 ? -22.32  -24.628 37.372  1 21.091 ? 546  PRO B CA  1 
ATOM   8402 C  C   . PRO B 1 554 ? -23.713 -24.908 37.949  1 22.833 ? 546  PRO B C   1 
ATOM   8403 O  O   . PRO B 1 554 ? -24.669 -24.392 37.405  1 24.79  ? 546  PRO B O   1 
ATOM   8404 C  CB  . PRO B 1 554 ? -22.081 -25.683 36.296  1 23.2   ? 546  PRO B CB  1 
ATOM   8405 C  CG  . PRO B 1 554 ? -20.945 -26.518 36.772  1 25.041 ? 546  PRO B CG  1 
ATOM   8406 C  CD  . PRO B 1 554 ? -20.232 -25.78  37.903  1 21.648 ? 546  PRO B CD  1 
ATOM   8407 N  N   . ASP B 1 555 ? -23.796 -25.601 39.097  1 25.516 ? 547  ASP B N   1 
ATOM   8408 C  CA  . ASP B 1 555 ? -25.038 -25.948 39.762  1 27.536 ? 547  ASP B CA  1 
ATOM   8409 C  C   . ASP B 1 555 ? -25.464 -24.862 40.742  1 26.66  ? 547  ASP B C   1 
ATOM   8410 O  O   . ASP B 1 555 ? -26.644 -24.805 41.096  1 26.824 ? 547  ASP B O   1 
ATOM   8411 C  CB  . ASP B 1 555 ? -25.03  -27.345 40.367  1 29.731 ? 547  ASP B CB  1 
ATOM   8412 C  CG  . ASP B 1 555 ? -24.689 -28.481 39.402  1 36.438 ? 547  ASP B CG  1 
ATOM   8413 O  OD1 . ASP B 1 555 ? -25.289 -28.569 38.31   1 33.224 ? 547  ASP B OD1 1 
ATOM   8414 O  OD2 . ASP B 1 555 ? -23.747 -29.219 39.719  1 37.124 ? 547  ASP B OD2 1 
ATOM   8415 N  N   . ALA B 1 556 ? -24.53  -23.977 41.124  1 22.313 ? 548  ALA B N   1 
ATOM   8416 C  CA  . ALA B 1 556 ? -24.79  -22.985 42.169  1 23.268 ? 548  ALA B CA  1 
ATOM   8417 C  C   . ALA B 1 556 ? -25.802 -21.904 41.726  1 23.113 ? 548  ALA B C   1 
ATOM   8418 O  O   . ALA B 1 556 ? -26.305 -21.285 42.65   1 26.502 ? 548  ALA B O   1 
ATOM   8419 C  CB  . ALA B 1 556 ? -23.488 -22.361 42.653  1 22.331 ? 548  ALA B CB  1 
ATOM   8420 O  OXT . ALA B 1 556 ? -25.977 -21.614 40.515  1 21.907 ? 548  ALA B OXT 1 
HETATM 8421 O  O1  . V9L C 2 .   ? -3.295  -6.633  46.273  1 42.841 ? 601  V9L A O1  1 
HETATM 8422 C  C1  . V9L C 2 .   ? -4.425  -7.325  46.528  1 24.705 ? 601  V9L A C1  1 
HETATM 8423 C  C2  . V9L C 2 .   ? -5.169  -6.941  47.652  1 23.446 ? 601  V9L A C2  1 
HETATM 8424 C  C3  . V9L C 2 .   ? -6.391  -7.572  47.944  1 20.544 ? 601  V9L A C3  1 
HETATM 8425 C  C4  . V9L C 2 .   ? -6.86   -8.546  47.126  1 21.611 ? 601  V9L A C4  1 
HETATM 8426 C  C5  . V9L C 2 .   ? -6.144  -8.93   45.991  1 21.853 ? 601  V9L A C5  1 
HETATM 8427 C  C6  . V9L C 2 .   ? -4.932  -8.334  45.642  1 23.647 ? 601  V9L A C6  1 
HETATM 8428 O  O2  . V9L C 2 .   ? -4.259  -8.687  44.471  1 21.098 ? 601  V9L A O2  1 
HETATM 8429 C  C7  . V9L C 2 .   ? -2.977  -8.147  44.094  1 15.065 ? 601  V9L A C7  1 
HETATM 8430 C  C8  . V9L C 2 .   ? -4.622  -5.895  48.514  1 25.775 ? 601  V9L A C8  1 
HETATM 8431 O  O3  . V9L C 2 .   ? -3.418  -5.572  48.533  1 22.453 ? 601  V9L A O3  1 
HETATM 8432 FE FE  . FE2 D 3 .   ? -1.878  -7.755  50.922  1 14.871 ? 602  FE2 A FE  1 
HETATM 8433 O  O1  . V9L E 2 .   ? 30.992  -2.087  14.299  1 47.671 ? 601  V9L B O1  1 
HETATM 8434 C  C1  . V9L E 2 .   ? 32.311  -2.322  14.095  1 26.79  ? 601  V9L B C1  1 
HETATM 8435 C  C2  . V9L E 2 .   ? 32.997  -1.634  13.066  1 24.827 ? 601  V9L B C2  1 
HETATM 8436 C  C3  . V9L E 2 .   ? 34.365  -1.866  12.844  1 20.099 ? 601  V9L B C3  1 
HETATM 8437 C  C4  . V9L E 2 .   ? 35.038  -2.779  13.583  1 20.646 ? 601  V9L B C4  1 
HETATM 8438 C  C5  . V9L E 2 .   ? 34.368  -3.432  14.635  1 20.991 ? 601  V9L B C5  1 
HETATM 8439 C  C6  . V9L E 2 .   ? 33.045  -3.184  14.963  1 24.405 ? 601  V9L B C6  1 
HETATM 8440 O  O2  . V9L E 2 .   ? 32.424  -3.868  16.002  1 24.751 ? 601  V9L B O2  1 
HETATM 8441 C  C7  . V9L E 2 .   ? 31.141  -3.475  16.55   1 25.446 ? 601  V9L B C7  1 
HETATM 8442 C  C8  . V9L E 2 .   ? 32.297  -0.677  12.211  1 21.026 ? 601  V9L B C8  1 
HETATM 8443 O  O3  . V9L E 2 .   ? 31.122  -0.431  12.369  1 22.799 ? 601  V9L B O3  1 
HETATM 8444 FE FE  . FE2 F 3 .   ? 29.988  -3.036  9.82    1 14.897 ? 602  FE2 B FE  1 
HETATM 8445 O  O   . HOH G 4 .   ? 6.206   -24.748 41.254  1 34.418 ? 701  HOH A O   1 
HETATM 8446 O  O   . HOH G 4 .   ? -18.219 -13.157 36.011  1 36.659 ? 702  HOH A O   1 
HETATM 8447 O  O   . HOH G 4 .   ? -17.529 -18.151 30.952  1 52.645 ? 703  HOH A O   1 
HETATM 8448 O  O   . HOH G 4 .   ? -1.678  12.453  48.563  1 45.413 ? 704  HOH A O   1 
HETATM 8449 O  O   . HOH G 4 .   ? -0.405  -29.907 42.828  1 35.256 ? 705  HOH A O   1 
HETATM 8450 O  O   . HOH G 4 .   ? -21.468 -11.512 53.168  1 60.219 ? 706  HOH A O   1 
HETATM 8451 O  O   . HOH G 4 .   ? 5.721   3.321   72.786  1 37.06  ? 707  HOH A O   1 
HETATM 8452 O  O   . HOH G 4 .   ? -6.713  -10.228 45.216  1 18.777 ? 708  HOH A O   1 
HETATM 8453 O  O   . HOH G 4 .   ? 22.528  -18.42  44.869  1 37.858 ? 709  HOH A O   1 
HETATM 8454 O  O   . HOH G 4 .   ? -2.34   -2.682  21.09   1 29.926 ? 710  HOH A O   1 
HETATM 8455 O  O   . HOH G 4 .   ? -7.043  -15.909 75.649  1 28.076 ? 711  HOH A O   1 
HETATM 8456 O  O   . HOH G 4 .   ? 13.269  10.269  40.083  1 28.602 ? 712  HOH A O   1 
HETATM 8457 O  O   . HOH G 4 .   ? 4.972   -28.394 42.979  1 42.818 ? 713  HOH A O   1 
HETATM 8458 O  O   . HOH G 4 .   ? 7.829   2.906   37.864  1 37.746 ? 714  HOH A O   1 
HETATM 8459 O  O   . HOH G 4 .   ? 24.652  4.604   37.988  1 35.335 ? 715  HOH A O   1 
HETATM 8460 O  O   . HOH G 4 .   ? 9.784   -6.458  64.658  1 16.109 ? 716  HOH A O   1 
HETATM 8461 O  O   . HOH G 4 .   ? 18.457  5.859   62.156  1 32.653 ? 717  HOH A O   1 
HETATM 8462 O  O   . HOH G 4 .   ? -23.412 -5.518  52.237  1 25.218 ? 718  HOH A O   1 
HETATM 8463 O  O   . HOH G 4 .   ? 32.697  -28.321 26.305  1 30.663 ? 719  HOH A O   1 
HETATM 8464 O  O   . HOH G 4 .   ? 9.394   17.437  49.922  1 49.238 ? 720  HOH A O   1 
HETATM 8465 O  O   . HOH G 4 .   ? 27.111  -3.54   59.578  1 33.725 ? 721  HOH A O   1 
HETATM 8466 O  O   . HOH G 4 .   ? 23.958  -5.524  65.561  1 42.123 ? 722  HOH A O   1 
HETATM 8467 O  O   . HOH G 4 .   ? -14.584 7.781   49.36   1 18.548 ? 723  HOH A O   1 
HETATM 8468 O  O   . HOH G 4 .   ? 3.159   6.262   45.802  1 51.527 ? 724  HOH A O   1 
HETATM 8469 O  O   . HOH G 4 .   ? 21.506  4.134   56.032  1 22.951 ? 725  HOH A O   1 
HETATM 8470 O  O   . HOH G 4 .   ? 15.141  6.54    47.116  1 22.281 ? 726  HOH A O   1 
HETATM 8471 O  O   . HOH G 4 .   ? -12.938 -19.386 72.846  1 23.469 ? 727  HOH A O   1 
HETATM 8472 O  O   . HOH G 4 .   ? 3.734   -17.646 68.146  1 18.538 ? 728  HOH A O   1 
HETATM 8473 O  O   . HOH G 4 .   ? -3.526  1.323   72.784  1 18.056 ? 729  HOH A O   1 
HETATM 8474 O  O   . HOH G 4 .   ? 4.31    -1.884  27.192  1 38.335 ? 730  HOH A O   1 
HETATM 8475 O  O   . HOH G 4 .   ? 16.579  -0.402  29.308  1 34.626 ? 731  HOH A O   1 
HETATM 8476 O  O   . HOH G 4 .   ? -13.414 -26.95  71.868  1 27.979 ? 732  HOH A O   1 
HETATM 8477 O  O   . HOH G 4 .   ? 9.307   -2.747  47.724  1 12.743 ? 733  HOH A O   1 
HETATM 8478 O  O   . HOH G 4 .   ? 0.924   8.505   12.306  1 30.505 ? 734  HOH A O   1 
HETATM 8479 O  O   . HOH G 4 .   ? -7.247  -17.437 20.588  1 33.895 ? 735  HOH A O   1 
HETATM 8480 O  O   . HOH G 4 .   ? 2.119   7.183   68.137  1 36.504 ? 736  HOH A O   1 
HETATM 8481 O  O   . HOH G 4 .   ? -15.636 -12.714 75.25   1 28.316 ? 737  HOH A O   1 
HETATM 8482 O  O   . HOH G 4 .   ? 5.219   -14.359 53.044  1 17.787 ? 738  HOH A O   1 
HETATM 8483 O  O   . HOH G 4 .   ? 16.895  -16.562 48.957  1 15.958 ? 739  HOH A O   1 
HETATM 8484 O  O   . HOH G 4 .   ? 12.095  -24.574 46.68   1 18.996 ? 740  HOH A O   1 
HETATM 8485 O  O   . HOH G 4 .   ? -2.003  -32.902 64.026  1 29.685 ? 741  HOH A O   1 
HETATM 8486 O  O   . HOH G 4 .   ? 4.597   -0.335  34.745  1 19.44  ? 742  HOH A O   1 
HETATM 8487 O  O   . HOH G 4 .   ? 0.386   -8.156  56.796  1 15.406 ? 743  HOH A O   1 
HETATM 8488 O  O   . HOH G 4 .   ? -29.458 -15.434 38.005  1 28.329 ? 744  HOH A O   1 
HETATM 8489 O  O   . HOH G 4 .   ? -0.391  -0.629  21.664  1 51.605 ? 745  HOH A O   1 
HETATM 8490 O  O   . HOH G 4 .   ? 1.006   -15.044 35.987  1 12.523 ? 746  HOH A O   1 
HETATM 8491 O  O   . HOH G 4 .   ? -1.268  -14.788 76.608  1 28.504 ? 747  HOH A O   1 
HETATM 8492 O  O   . HOH G 4 .   ? 6.322   -24.967 34.299  1 13.682 ? 748  HOH A O   1 
HETATM 8493 O  O   . HOH G 4 .   ? -15.622 -27.076 62.625  1 23.085 ? 749  HOH A O   1 
HETATM 8494 O  O   . HOH G 4 .   ? 0.787   -31.329 53.147  1 30.081 ? 750  HOH A O   1 
HETATM 8495 O  O   . HOH G 4 .   ? 7.94    -13.761 27.781  1 14.962 ? 751  HOH A O   1 
HETATM 8496 O  O   . HOH G 4 .   ? -13.878 -20.086 46.342  1 9.974  ? 752  HOH A O   1 
HETATM 8497 O  O   . HOH G 4 .   ? -15.305 6.166   51.469  1 23.249 ? 753  HOH A O   1 
HETATM 8498 O  O   . HOH G 4 .   ? 3.247   -7.527  58.232  1 19.391 ? 754  HOH A O   1 
HETATM 8499 O  O   . HOH G 4 .   ? 2.304   -20.456 70.618  1 35.44  ? 755  HOH A O   1 
HETATM 8500 O  O   . HOH G 4 .   ? 56.326  -11.125 15.478  1 23.294 ? 756  HOH A O   1 
HETATM 8501 O  O   . HOH G 4 .   ? -10.786 -1.225  49.593  1 31.337 ? 757  HOH A O   1 
HETATM 8502 O  O   . HOH G 4 .   ? -24.561 -12.51  57.24   1 29.105 ? 758  HOH A O   1 
HETATM 8503 O  O   . HOH G 4 .   ? 19.721  -9.721  69.354  1 45.874 ? 759  HOH A O   1 
HETATM 8504 O  O   . HOH G 4 .   ? -13.024 -15.907 43.36   1 15.614 ? 760  HOH A O   1 
HETATM 8505 O  O   . HOH G 4 .   ? 47.518  -20.222 19.589  1 42.574 ? 761  HOH A O   1 
HETATM 8506 O  O   . HOH G 4 .   ? 16.621  -25.623 44.458  1 19.939 ? 762  HOH A O   1 
HETATM 8507 O  O   . HOH G 4 .   ? 6.994   -10.899 56.054  1 25.59  ? 763  HOH A O   1 
HETATM 8508 O  O   . HOH G 4 .   ? 25.911  0.047   56.48   1 41.471 ? 764  HOH A O   1 
HETATM 8509 O  O   . HOH G 4 .   ? -18.647 -25.603 73.221  1 42.521 ? 765  HOH A O   1 
HETATM 8510 O  O   . HOH G 4 .   ? 6.822   -19.6   36.06   1 12.179 ? 766  HOH A O   1 
HETATM 8511 O  O   . HOH G 4 .   ? 2.047   -25.76  43.864  1 38.921 ? 767  HOH A O   1 
HETATM 8512 O  O   . HOH G 4 .   ? 25.629  -9.371  49.796  1 24.469 ? 768  HOH A O   1 
HETATM 8513 O  O   . HOH G 4 .   ? -12.686 -14.113 74.796  1 30.833 ? 769  HOH A O   1 
HETATM 8514 O  O   . HOH G 4 .   ? 4.262   -25.088 31.142  1 27.002 ? 770  HOH A O   1 
HETATM 8515 O  O   . HOH G 4 .   ? 20.665  -11.842 57.923  1 30.236 ? 771  HOH A O   1 
HETATM 8516 O  O   . HOH G 4 .   ? 40.634  -15.966 16.417  1 17.532 ? 772  HOH A O   1 
HETATM 8517 O  O   . HOH G 4 .   ? 42.997  -22.866 14.164  1 28.714 ? 773  HOH A O   1 
HETATM 8518 O  O   . HOH G 4 .   ? -10.959 -7.676  34.936  1 28.264 ? 774  HOH A O   1 
HETATM 8519 O  O   . HOH G 4 .   ? -22.364 -7.919  31.490  1 35.498 ? 775  HOH A O   1 
HETATM 8520 O  O   . HOH G 4 .   ? -3.622  11.012  58.356  1 21.304 ? 776  HOH A O   1 
HETATM 8521 O  O   . HOH G 4 .   ? 2.079   4.898   45.924  1 18.362 ? 777  HOH A O   1 
HETATM 8522 O  O   . HOH G 4 .   ? 4.874   2.639   43.277  1 18.242 ? 778  HOH A O   1 
HETATM 8523 O  O   . HOH G 4 .   ? 12.866  -12.699 56.287  1 20.268 ? 779  HOH A O   1 
HETATM 8524 O  O   . HOH G 4 .   ? -18.624 -3.17   43.753  1 15.525 ? 780  HOH A O   1 
HETATM 8525 O  O   . HOH G 4 .   ? 1.623   -4.01   67.652  1 26.014 ? 781  HOH A O   1 
HETATM 8526 O  O   . HOH G 4 .   ? -4.603  -3.876  35.528  1 17.214 ? 782  HOH A O   1 
HETATM 8527 O  O   . HOH G 4 .   ? 18.881  -24.254 35.965  1 32.083 ? 783  HOH A O   1 
HETATM 8528 O  O   . HOH G 4 .   ? -0.825  -25.733 49.034  1 13.571 ? 784  HOH A O   1 
HETATM 8529 O  O   . HOH G 4 .   ? 16.022  -0.015  69.139  1 41.144 ? 785  HOH A O   1 
HETATM 8530 O  O   . HOH G 4 .   ? -20.895 -24.987 55.21   1 27.988 ? 786  HOH A O   1 
HETATM 8531 O  O   . HOH G 4 .   ? -21.325 1.381   59.975  1 36.312 ? 787  HOH A O   1 
HETATM 8532 O  O   . HOH G 4 .   ? 19.804  8.428   50.881  1 45.664 ? 788  HOH A O   1 
HETATM 8533 O  O   . HOH G 4 .   ? -27.555 1.497   51.422  1 44.616 ? 789  HOH A O   1 
HETATM 8534 O  O   . HOH G 4 .   ? -17.823 -28.854 68.972  1 30.252 ? 790  HOH A O   1 
HETATM 8535 O  O   . HOH G 4 .   ? 13.899  -10.734 60.298  1 18.345 ? 791  HOH A O   1 
HETATM 8536 O  O   . HOH G 4 .   ? -5.161  -12.539 51.222  1 13.007 ? 792  HOH A O   1 
HETATM 8537 O  O   . HOH G 4 .   ? 3.354   -2.121  64.669  1 21.183 ? 793  HOH A O   1 
HETATM 8538 O  O   . HOH G 4 .   ? -28.271 -12.498 38.852  1 18.43  ? 794  HOH A O   1 
HETATM 8539 O  O   . HOH G 4 .   ? -4.995  -19.771 37.71   1 15.054 ? 795  HOH A O   1 
HETATM 8540 O  O   . HOH G 4 .   ? 9.866   -6.949  70.892  1 26.192 ? 796  HOH A O   1 
HETATM 8541 O  O   . HOH G 4 .   ? -5.465  0.102   71.167  1 19.53  ? 797  HOH A O   1 
HETATM 8542 O  O   . HOH G 4 .   ? 27.013  -0.384  52.571  1 24.134 ? 798  HOH A O   1 
HETATM 8543 O  O   . HOH G 4 .   ? -1.881  -15.17  35.944  1 14.089 ? 799  HOH A O   1 
HETATM 8544 O  O   . HOH G 4 .   ? -25.988 -4.883  49.389  1 35.978 ? 800  HOH A O   1 
HETATM 8545 O  O   . HOH G 4 .   ? 27.722  -5.904  60.697  1 46.524 ? 801  HOH A O   1 
HETATM 8546 O  O   . HOH G 4 .   ? 11.584  -13.773 68.843  1 25.137 ? 802  HOH A O   1 
HETATM 8547 O  O   . HOH G 4 .   ? 0.844   -5.53   31.706  1 19.894 ? 803  HOH A O   1 
HETATM 8548 O  O   . HOH G 4 .   ? 13.058  -6.46   71.056  1 24.317 ? 804  HOH A O   1 
HETATM 8549 O  O   . HOH G 4 .   ? -2.402  -30.366 66.477  1 34.601 ? 805  HOH A O   1 
HETATM 8550 O  O   . HOH G 4 .   ? 3.563   4.958   69.909  1 27.407 ? 806  HOH A O   1 
HETATM 8551 O  O   . HOH G 4 .   ? 4.824   -30.841 63.805  1 32.091 ? 807  HOH A O   1 
HETATM 8552 O  O   . HOH G 4 .   ? 12.477  -1.81   69.754  1 30.276 ? 808  HOH A O   1 
HETATM 8553 O  O   . HOH G 4 .   ? -20.886 -23.667 51.718  1 24.824 ? 809  HOH A O   1 
HETATM 8554 O  O   . HOH G 4 .   ? 0.601   8.311   41.834  1 31.38  ? 810  HOH A O   1 
HETATM 8555 O  O   . HOH G 4 .   ? 38.422  -21.087 34.723  1 31.896 ? 811  HOH A O   1 
HETATM 8556 O  O   . HOH G 4 .   ? 16.15   2.556   62.058  1 31.267 ? 812  HOH A O   1 
HETATM 8557 O  O   . HOH G 4 .   ? 13.646  -24.859 36.891  1 24.917 ? 813  HOH A O   1 
HETATM 8558 O  O   . HOH G 4 .   ? -15.538 -5.094  58.174  1 42.759 ? 814  HOH A O   1 
HETATM 8559 O  O   . HOH G 4 .   ? -23.581 -13.223 50.341  1 25.334 ? 815  HOH A O   1 
HETATM 8560 O  O   . HOH G 4 .   ? 1.202   2.618   28.718  1 41.536 ? 816  HOH A O   1 
HETATM 8561 O  O   . HOH G 4 .   ? 27.251  3.88    50.743  1 32.201 ? 817  HOH A O   1 
HETATM 8562 O  O   . HOH G 4 .   ? -12.951 6.07    48.161  1 24.984 ? 818  HOH A O   1 
HETATM 8563 O  O   . HOH G 4 .   ? -1.31   -30.689 45.066  1 34.39  ? 819  HOH A O   1 
HETATM 8564 O  O   . HOH G 4 .   ? -2.546  -12.987 30.108  1 15.216 ? 820  HOH A O   1 
HETATM 8565 O  O   . HOH G 4 .   ? -16.39  3.282   41.679  1 28.984 ? 821  HOH A O   1 
HETATM 8566 O  O   . HOH G 4 .   ? -11.73  -16.75  70.332  1 18.895 ? 822  HOH A O   1 
HETATM 8567 O  O   . HOH G 4 .   ? -16.377 -6.59   69.779  1 20.106 ? 823  HOH A O   1 
HETATM 8568 O  O   . HOH G 4 .   ? 10.315  -7.517  56.978  1 15.474 ? 824  HOH A O   1 
HETATM 8569 O  O   . HOH G 4 .   ? 3.843   1.137   37.208  1 26.623 ? 825  HOH A O   1 
HETATM 8570 O  O   . HOH G 4 .   ? 2.173   -13.855 54.063  1 30.265 ? 826  HOH A O   1 
HETATM 8571 O  O   . HOH G 4 .   ? 9.187   -22.876 59.055  1 20.831 ? 827  HOH A O   1 
HETATM 8572 O  O   . HOH G 4 .   ? 16.369  -26.209 42.007  1 28.302 ? 828  HOH A O   1 
HETATM 8573 O  O   . HOH G 4 .   ? -7.986  -11.41  30.94   1 18.751 ? 829  HOH A O   1 
HETATM 8574 O  O   . HOH G 4 .   ? -5.176  -12.881 33.063  1 13.38  ? 830  HOH A O   1 
HETATM 8575 O  O   . HOH G 4 .   ? 6.662   -29.714 38.122  1 23.351 ? 831  HOH A O   1 
HETATM 8576 O  O   . HOH G 4 .   ? -22.399 -19.137 47.444  1 15.516 ? 832  HOH A O   1 
HETATM 8577 O  O   . HOH G 4 .   ? 1.136   -14.172 27.477  1 15.445 ? 833  HOH A O   1 
HETATM 8578 O  O   . HOH G 4 .   ? -5.458  -10.817 29.674  1 14.166 ? 834  HOH A O   1 
HETATM 8579 O  O   . HOH G 4 .   ? -3.184  4.415   56.346  1 15.105 ? 835  HOH A O   1 
HETATM 8580 O  O   . HOH G 4 .   ? -7.578  -24.434 36.28   1 15.001 ? 836  HOH A O   1 
HETATM 8581 O  O   . HOH G 4 .   ? -15.209 -8      40.69   1 15.199 ? 837  HOH A O   1 
HETATM 8582 O  O   . HOH G 4 .   ? -8.106  -8.045  55.965  1 11.799 ? 838  HOH A O   1 
HETATM 8583 O  O   . HOH G 4 .   ? -11.346 -20.522 44.724  1 11.219 ? 839  HOH A O   1 
HETATM 8584 O  O   . HOH G 4 .   ? -7.931  0.639   71.902  1 22.886 ? 840  HOH A O   1 
HETATM 8585 O  O   . HOH G 4 .   ? -13.961 6.865   60.978  1 30.391 ? 841  HOH A O   1 
HETATM 8586 O  O   . HOH G 4 .   ? 12.215  -10.407 56.363  1 25.335 ? 842  HOH A O   1 
HETATM 8587 O  O   . HOH G 4 .   ? -0.287  -18.391 21.27   1 27.13  ? 843  HOH A O   1 
HETATM 8588 O  O   . HOH G 4 .   ? -7.248  -14.173 52.464  1 12.224 ? 844  HOH A O   1 
HETATM 8589 O  O   . HOH G 4 .   ? 13.041  -15.994 66.069  1 22.61  ? 845  HOH A O   1 
HETATM 8590 O  O   . HOH G 4 .   ? 12.749  -19.642 65.644  1 40.004 ? 846  HOH A O   1 
HETATM 8591 O  O   . HOH G 4 .   ? -22.462 -16.608 32.725  1 30.262 ? 847  HOH A O   1 
HETATM 8592 O  O   . HOH G 4 .   ? -10.172 -10.969 36.309  1 19.484 ? 848  HOH A O   1 
HETATM 8593 O  O   . HOH G 4 .   ? 4.24    -10.864 65.948  1 21.4   ? 849  HOH A O   1 
HETATM 8594 O  O   . HOH G 4 .   ? -8.511  -4.063  78.283  1 21.02  ? 850  HOH A O   1 
HETATM 8595 O  O   . HOH G 4 .   ? 6.614   -17.833 32.571  1 21.449 ? 851  HOH A O   1 
HETATM 8596 O  O   . HOH G 4 .   ? 5.895   -19.615 30.818  1 17.47  ? 852  HOH A O   1 
HETATM 8597 O  O   . HOH G 4 .   ? -14.851 -2.721  74.667  1 27.345 ? 853  HOH A O   1 
HETATM 8598 O  O   . HOH G 4 .   ? 20.536  -14.536 55.37   1 27.858 ? 854  HOH A O   1 
HETATM 8599 O  O   . HOH G 4 .   ? 7.218   -27.26  65.003  1 33.382 ? 855  HOH A O   1 
HETATM 8600 O  O   . HOH G 4 .   ? 1.614   11.109  63.479  1 31.51  ? 856  HOH A O   1 
HETATM 8601 O  O   . HOH G 4 .   ? 8.457   -0.203  40.046  1 19.823 ? 857  HOH A O   1 
HETATM 8602 O  O   . HOH G 4 .   ? -14.84  -7.039  25.232  1 20.969 ? 858  HOH A O   1 
HETATM 8603 O  O   . HOH G 4 .   ? 27.41   -21.651 43.703  1 48.526 ? 859  HOH A O   1 
HETATM 8604 O  O   . HOH G 4 .   ? -19.622 -14.926 72.901  1 45.621 ? 860  HOH A O   1 
HETATM 8605 O  O   . HOH G 4 .   ? -14.96  -0.968  38.736  1 22.676 ? 861  HOH A O   1 
HETATM 8606 O  O   . HOH G 4 .   ? 12.795  -15.343 33.751  1 16.384 ? 862  HOH A O   1 
HETATM 8607 O  O   . HOH G 4 .   ? -5.517  2.116   39.754  1 32.024 ? 863  HOH A O   1 
HETATM 8608 O  O   . HOH G 4 .   ? -10.572 -4.913  73.976  1 15.88  ? 864  HOH A O   1 
HETATM 8609 O  O   . HOH G 4 .   ? 4.865   -27.866 64.317  1 19.66  ? 865  HOH A O   1 
HETATM 8610 O  O   . HOH G 4 .   ? -25.23  -4.104  41.976  1 29.741 ? 866  HOH A O   1 
HETATM 8611 O  O   . HOH G 4 .   ? 54.269  -12.427 21.706  1 18.446 ? 867  HOH A O   1 
HETATM 8612 O  O   . HOH G 4 .   ? 0.471   -10.044 24.951  1 39.385 ? 868  HOH A O   1 
HETATM 8613 O  O   . HOH G 4 .   ? 4.089   9.172   23.587  1 51.01  ? 869  HOH A O   1 
HETATM 8614 O  O   . HOH G 4 .   ? -11.109 -16.189 49.076  1 14.467 ? 870  HOH A O   1 
HETATM 8615 O  O   . HOH G 4 .   ? -7.439  -11.355 38.755  1 15.526 ? 871  HOH A O   1 
HETATM 8616 O  O   . HOH G 4 .   ? -10.397 -21.833 73.528  1 28.162 ? 872  HOH A O   1 
HETATM 8617 O  O   . HOH G 4 .   ? 8.983   -27.398 30.578  1 39.335 ? 873  HOH A O   1 
HETATM 8618 O  O   . HOH G 4 .   ? -13.835 -5.206  32.15   1 21.936 ? 874  HOH A O   1 
HETATM 8619 O  O   . HOH G 4 .   ? -3.91   -18.428 44.242  1 14.413 ? 875  HOH A O   1 
HETATM 8620 O  O   . HOH G 4 .   ? 13.645  -22.183 33.483  1 28.006 ? 876  HOH A O   1 
HETATM 8621 O  O   . HOH G 4 .   ? 48.828  -18.409 18.342  1 42.288 ? 877  HOH A O   1 
HETATM 8622 O  O   . HOH G 4 .   ? 6.952   -10.405 33.613  1 15.366 ? 878  HOH A O   1 
HETATM 8623 O  O   . HOH G 4 .   ? -5.78   -21.446 25.363  1 17.553 ? 879  HOH A O   1 
HETATM 8624 O  O   . HOH G 4 .   ? 0.961   -9.398  60.196  1 17.897 ? 880  HOH A O   1 
HETATM 8625 O  O   . HOH G 4 .   ? 22.037  -14.995 41.815  1 13.678 ? 881  HOH A O   1 
HETATM 8626 O  O   . HOH G 4 .   ? 17.111  -29.297 46.726  1 39.051 ? 882  HOH A O   1 
HETATM 8627 O  O   . HOH G 4 .   ? -4.538  8.807   51.211  1 22.524 ? 883  HOH A O   1 
HETATM 8628 O  O   . HOH G 4 .   ? -2.06   -7.917  48.853  1 13.522 ? 884  HOH A O   1 
HETATM 8629 O  O   . HOH G 4 .   ? -17.5   -27.307 56.918  1 23.252 ? 885  HOH A O   1 
HETATM 8630 O  O   . HOH G 4 .   ? 8.328   -5.7    49.381  1 14.039 ? 886  HOH A O   1 
HETATM 8631 O  O   . HOH G 4 .   ? -4.093  -23.743 31.781  1 14.841 ? 887  HOH A O   1 
HETATM 8632 O  O   . HOH G 4 .   ? 9.648   -24.34  45.342  1 16.381 ? 888  HOH A O   1 
HETATM 8633 O  O   . HOH G 4 .   ? 7.062   7.777   67.22   1 37.313 ? 889  HOH A O   1 
HETATM 8634 O  O   . HOH G 4 .   ? 19.442  -15.774 31.555  1 25.844 ? 890  HOH A O   1 
HETATM 8635 O  O   . HOH G 4 .   ? 7.791   -4.137  42.543  1 22.46  ? 891  HOH A O   1 
HETATM 8636 O  O   . HOH G 4 .   ? -23.04  -7.176  48.485  1 21.844 ? 892  HOH A O   1 
HETATM 8637 O  O   . HOH G 4 .   ? 23.293  -20.396 38.66   1 38.96  ? 893  HOH A O   1 
HETATM 8638 O  O   . HOH G 4 .   ? -4.938  -12.101 47.241  1 12.403 ? 894  HOH A O   1 
HETATM 8639 O  O   . HOH G 4 .   ? -13.182 3.74    72.601  1 37.036 ? 895  HOH A O   1 
HETATM 8640 O  O   . HOH G 4 .   ? -4.79   -14.497 75.737  1 24.92  ? 896  HOH A O   1 
HETATM 8641 O  O   . HOH G 4 .   ? 1.629   -0.707  44.005  1 15.324 ? 897  HOH A O   1 
HETATM 8642 O  O   . HOH G 4 .   ? -20.553 -27.022 53.676  1 37.571 ? 898  HOH A O   1 
HETATM 8643 O  O   . HOH G 4 .   ? 7.764   -15.113 59.823  1 22.6   ? 899  HOH A O   1 
HETATM 8644 O  O   . HOH G 4 .   ? 19.902  -0.105  64.104  1 25.984 ? 900  HOH A O   1 
HETATM 8645 O  O   . HOH G 4 .   ? 6.327   12.655  39.956  1 34.347 ? 901  HOH A O   1 
HETATM 8646 O  O   . HOH G 4 .   ? -6.827  -0.753  35.941  1 17.494 ? 902  HOH A O   1 
HETATM 8647 O  O   . HOH G 4 .   ? -16.105 -27.405 65.16   1 22.73  ? 903  HOH A O   1 
HETATM 8648 O  O   . HOH G 4 .   ? -15.885 -16.862 53.569  1 17.044 ? 904  HOH A O   1 
HETATM 8649 O  O   . HOH G 4 .   ? 2.598   -5.393  54.124  1 17.102 ? 905  HOH A O   1 
HETATM 8650 O  O   . HOH G 4 .   ? 26.442  -12.591 51.178  1 21.139 ? 906  HOH A O   1 
HETATM 8651 O  O   . HOH G 4 .   ? 13.514  10.194  64.2    1 57.451 ? 907  HOH A O   1 
HETATM 8652 O  O   . HOH G 4 .   ? 16.993  6.006   44.683  1 21.318 ? 908  HOH A O   1 
HETATM 8653 O  O   . HOH G 4 .   ? -23.088 -2.221  49.291  1 22.535 ? 909  HOH A O   1 
HETATM 8654 O  O   . HOH G 4 .   ? 5.19    -4.563  27.342  1 18.261 ? 910  HOH A O   1 
HETATM 8655 O  O   . HOH G 4 .   ? 25.606  -8.986  32.848  1 14.104 ? 911  HOH A O   1 
HETATM 8656 O  O   . HOH G 4 .   ? -7.172  7.453   51.885  1 22.475 ? 912  HOH A O   1 
HETATM 8657 O  O   . HOH G 4 .   ? 22.474  -20.891 52.316  1 30.046 ? 913  HOH A O   1 
HETATM 8658 O  O   . HOH G 4 .   ? 20      -18.51  33.453  1 26.534 ? 914  HOH A O   1 
HETATM 8659 O  O   . HOH G 4 .   ? 7.435   -21.762 34.363  1 22.968 ? 915  HOH A O   1 
HETATM 8660 O  O   . HOH G 4 .   ? -20.698 13.679  40.053  1 18.395 ? 916  HOH A O   1 
HETATM 8661 O  O   . HOH G 4 .   ? -21.989 -19.768 52.827  1 20.017 ? 917  HOH A O   1 
HETATM 8662 O  O   . HOH G 4 .   ? -6.973  -30.663 48.089  1 21.06  ? 918  HOH A O   1 
HETATM 8663 O  O   . HOH G 4 .   ? -14.189 -24.349 32.565  1 28.305 ? 919  HOH A O   1 
HETATM 8664 O  O   . HOH G 4 .   ? 0.855   0.893   46.121  1 20.463 ? 920  HOH A O   1 
HETATM 8665 O  O   . HOH G 4 .   ? 20.797  -23.019 51.103  1 35.946 ? 921  HOH A O   1 
HETATM 8666 O  O   . HOH G 4 .   ? -11.568 -8.891  30.514  1 13.529 ? 922  HOH A O   1 
HETATM 8667 O  O   . HOH G 4 .   ? 15.274  10.686  53.763  1 21.828 ? 923  HOH A O   1 
HETATM 8668 O  O   . HOH G 4 .   ? 15.697  11.334  49.619  1 25.76  ? 924  HOH A O   1 
HETATM 8669 O  O   . HOH G 4 .   ? -29.171 -18.889 38.653  1 37.224 ? 925  HOH A O   1 
HETATM 8670 O  O   . HOH G 4 .   ? 25.701  -6.374  41.47   1 14.657 ? 926  HOH A O   1 
HETATM 8671 O  O   . HOH G 4 .   ? 29.777  -4.655  53.388  1 34.363 ? 927  HOH A O   1 
HETATM 8672 O  O   . HOH G 4 .   ? -4.152  -10.841 22.964  1 15.137 ? 928  HOH A O   1 
HETATM 8673 O  O   . HOH G 4 .   ? 31.673  -25.8   33.194  1 35.463 ? 929  HOH A O   1 
HETATM 8674 O  O   . HOH G 4 .   ? 55.345  -21.265 22.379  1 40.638 ? 930  HOH A O   1 
HETATM 8675 O  O   . HOH G 4 .   ? -17.986 -7.046  26.343  1 31.779 ? 931  HOH A O   1 
HETATM 8676 O  O   . HOH G 4 .   ? -12.095 -6.377  37.779  1 12.842 ? 932  HOH A O   1 
HETATM 8677 O  O   . HOH G 4 .   ? -2.51   -28.604 68.028  1 37.454 ? 933  HOH A O   1 
HETATM 8678 O  O   . HOH G 4 .   ? -15.293 -6.463  73.483  1 26.918 ? 934  HOH A O   1 
HETATM 8679 O  O   . HOH G 4 .   ? -3.556  -5.314  37.474  1 16.606 ? 935  HOH A O   1 
HETATM 8680 O  O   . HOH G 4 .   ? -7.173  -26.889 65.145  1 20.374 ? 936  HOH A O   1 
HETATM 8681 O  O   . HOH G 4 .   ? 3.126   -31.831 47.092  1 34.171 ? 937  HOH A O   1 
HETATM 8682 O  O   . HOH G 4 .   ? -6.494  -10.205 24.517  1 18.7   ? 938  HOH A O   1 
HETATM 8683 O  O   . HOH G 4 .   ? -10.397 -25.863 37.994  1 24.139 ? 939  HOH A O   1 
HETATM 8684 O  O   . HOH G 4 .   ? -7.568  -13.856 39.813  1 11.149 ? 940  HOH A O   1 
HETATM 8685 O  O   . HOH G 4 .   ? -7.267  -5.939  21.937  1 44.004 ? 941  HOH A O   1 
HETATM 8686 O  O   . HOH G 4 .   ? -11.923 -17.111 21.593  1 40.567 ? 942  HOH A O   1 
HETATM 8687 O  O   . HOH G 4 .   ? -0.021  -29.111 40.344  1 22.101 ? 943  HOH A O   1 
HETATM 8688 O  O   . HOH G 4 .   ? 17.388  -10.613 68.321  1 34.844 ? 944  HOH A O   1 
HETATM 8689 O  O   . HOH G 4 .   ? 10.021  -10.121 54.455  1 14.854 ? 945  HOH A O   1 
HETATM 8690 O  O   . HOH G 4 .   ? -22.439 -1.284  42.439  1 30.298 ? 946  HOH A O   1 
HETATM 8691 O  O   . HOH G 4 .   ? -23.053 -12.982 53.028  1 21.381 ? 947  HOH A O   1 
HETATM 8692 O  O   . HOH G 4 .   ? 9.155   -17.003 53.854  1 17.965 ? 948  HOH A O   1 
HETATM 8693 O  O   . HOH G 4 .   ? -9.303  -19.61  41.472  1 16.181 ? 949  HOH A O   1 
HETATM 8694 O  O   . HOH G 4 .   ? -5.576  9.11    43.715  1 31.137 ? 950  HOH A O   1 
HETATM 8695 O  O   . HOH G 4 .   ? 11.876  -9.492  58.792  1 22.891 ? 951  HOH A O   1 
HETATM 8696 O  O   . HOH G 4 .   ? -20.656 -13.431 30.591  1 21.546 ? 952  HOH A O   1 
HETATM 8697 O  O   . HOH G 4 .   ? -5.835  10.541  52.649  1 39.367 ? 953  HOH A O   1 
HETATM 8698 O  O   . HOH G 4 .   ? -31.705 4.876   50.281  1 55.424 ? 954  HOH A O   1 
HETATM 8699 O  O   . HOH G 4 .   ? -14.917 -7.365  43.473  1 18.61  ? 955  HOH A O   1 
HETATM 8700 O  O   . HOH G 4 .   ? -10.652 -13.327 38.41   1 11.485 ? 956  HOH A O   1 
HETATM 8701 O  O   . HOH G 4 .   ? 40.953  -21.31  23.392  1 32.028 ? 957  HOH A O   1 
HETATM 8702 O  O   . HOH G 4 .   ? -10.821 -10.911 47.299  1 15.695 ? 958  HOH A O   1 
HETATM 8703 O  O   . HOH G 4 .   ? 0.73    -11.27  62.314  1 20.806 ? 959  HOH A O   1 
HETATM 8704 O  O   . HOH G 4 .   ? 0.436   -2.879  42.072  1 18.649 ? 960  HOH A O   1 
HETATM 8705 O  O   . HOH G 4 .   ? 9.118   -11.456 71.8    1 26.431 ? 961  HOH A O   1 
HETATM 8706 O  O   . HOH G 4 .   ? 42.089  -19.761 21.657  1 31.514 ? 962  HOH A O   1 
HETATM 8707 O  O   . HOH G 4 .   ? 5.882   -11.625 27.916  1 13.584 ? 963  HOH A O   1 
HETATM 8708 O  O   . HOH G 4 .   ? -2.001  -23.142 49.002  1 15.67  ? 964  HOH A O   1 
HETATM 8709 O  O   . HOH G 4 .   ? 24.211  -14.452 60.925  1 35.514 ? 965  HOH A O   1 
HETATM 8710 O  O   . HOH G 4 .   ? -4.12   -24.679 23.381  1 39.377 ? 966  HOH A O   1 
HETATM 8711 O  O   . HOH G 4 .   ? 23.89   -12.404 43.396  1 22.899 ? 967  HOH A O   1 
HETATM 8712 O  O   . HOH G 4 .   ? 1.818   -11.57  55.307  1 20.172 ? 968  HOH A O   1 
HETATM 8713 O  O   . HOH G 4 .   ? 24.991  -17.038 31.72   1 17.347 ? 969  HOH A O   1 
HETATM 8714 O  O   . HOH G 4 .   ? -20.571 -4.133  40.167  1 25.24  ? 970  HOH A O   1 
HETATM 8715 O  O   . HOH G 4 .   ? -7.319  5.751   50.066  1 23.625 ? 971  HOH A O   1 
HETATM 8716 O  O   . HOH G 4 .   ? 6.476   -30.267 51.286  1 29.671 ? 972  HOH A O   1 
HETATM 8717 O  O   . HOH G 4 .   ? 22.099  -13.458 59.694  1 54.663 ? 973  HOH A O   1 
HETATM 8718 O  O   . HOH G 4 .   ? -13.076 -19.406 37.387  1 18.143 ? 974  HOH A O   1 
HETATM 8719 O  O   . HOH G 4 .   ? -14.451 -17.482 45.439  1 14.12  ? 975  HOH A O   1 
HETATM 8720 O  O   . HOH G 4 .   ? 21.585  -8.431  56.471  1 26.717 ? 976  HOH A O   1 
HETATM 8721 O  O   . HOH G 4 .   ? -16.618 13.391  42.601  1 29.889 ? 977  HOH A O   1 
HETATM 8722 O  O   . HOH G 4 .   ? -22.524 -20.135 33.489  1 37.065 ? 978  HOH A O   1 
HETATM 8723 O  O   . HOH G 4 .   ? -6.91   2.255   44.68   1 24.263 ? 979  HOH A O   1 
HETATM 8724 O  O   . HOH G 4 .   ? 54.261  -12.619 24.352  1 21.892 ? 980  HOH A O   1 
HETATM 8725 O  O   . HOH G 4 .   ? 17.461  9.387   49.2    1 28.802 ? 981  HOH A O   1 
HETATM 8726 O  O   . HOH G 4 .   ? -30.192 1.843   45.205  1 33.782 ? 982  HOH A O   1 
HETATM 8727 O  O   . HOH G 4 .   ? 21.753  -2.801  35.834  1 15.03  ? 983  HOH A O   1 
HETATM 8728 O  O   . HOH G 4 .   ? 20.841  -11.667 54.925  1 18.19  ? 984  HOH A O   1 
HETATM 8729 O  O   . HOH G 4 .   ? -19.031 -8.818  67.534  1 26.465 ? 985  HOH A O   1 
HETATM 8730 O  O   . HOH G 4 .   ? -24.673 -14.566 47.666  1 22.218 ? 986  HOH A O   1 
HETATM 8731 O  O   . HOH G 4 .   ? 4.246   -1.872  47.418  1 13.916 ? 987  HOH A O   1 
HETATM 8732 O  O   . HOH G 4 .   ? 23.444  -16.191 38.975  1 22.736 ? 988  HOH A O   1 
HETATM 8733 O  O   . HOH G 4 .   ? 33.027  -26.906 30.73   1 28.583 ? 989  HOH A O   1 
HETATM 8734 O  O   . HOH G 4 .   ? -19.9   2.278   61.681  1 22.249 ? 990  HOH A O   1 
HETATM 8735 O  O   . HOH G 4 .   ? 26.707  -10.433 60.069  1 44.579 ? 991  HOH A O   1 
HETATM 8736 O  O   . HOH G 4 .   ? 15.177  15.098  52.629  1 30.554 ? 992  HOH A O   1 
HETATM 8737 O  O   . HOH G 4 .   ? -19.345 6.346   44.04   1 27.684 ? 993  HOH A O   1 
HETATM 8738 O  O   . HOH G 4 .   ? 22.568  -24.297 49.499  1 25.458 ? 994  HOH A O   1 
HETATM 8739 O  O   . HOH G 4 .   ? -0.924  -32.573 55.432  1 21.964 ? 995  HOH A O   1 
HETATM 8740 O  O   . HOH G 4 .   ? 5.527   -14.69  58.226  1 15.146 ? 996  HOH A O   1 
HETATM 8741 O  O   . HOH G 4 .   ? -25.214 -0.606  49.429  1 25.109 ? 997  HOH A O   1 
HETATM 8742 O  O   . HOH G 4 .   ? -9.275  -10.075 33.001  1 13.421 ? 998  HOH A O   1 
HETATM 8743 O  O   . HOH G 4 .   ? 11.785  1.125   31.386  1 15.51  ? 999  HOH A O   1 
HETATM 8744 O  O   . HOH G 4 .   ? 17.127  5.971   33.521  1 31.114 ? 1000 HOH A O   1 
HETATM 8745 O  O   . HOH G 4 .   ? 35.582  -19.853 30.655  1 20.316 ? 1001 HOH A O   1 
HETATM 8746 O  O   . HOH G 4 .   ? 11.232  -23.387 31.492  1 27.875 ? 1002 HOH A O   1 
HETATM 8747 O  O   . HOH G 4 .   ? 3.438   2.53    34.758  1 31.43  ? 1003 HOH A O   1 
HETATM 8748 O  O   . HOH G 4 .   ? -20.719 -20.744 44.411  1 14.208 ? 1004 HOH A O   1 
HETATM 8749 O  O   . HOH G 4 .   ? -2.179  -0.426  29.528  1 33.606 ? 1005 HOH A O   1 
HETATM 8750 O  O   . HOH G 4 .   ? 19.593  2.702   34.494  1 20.163 ? 1006 HOH A O   1 
HETATM 8751 O  O   . HOH G 4 .   ? -9.826  8.849   46.371  1 35.191 ? 1007 HOH A O   1 
HETATM 8752 O  O   . HOH G 4 .   ? 6.96    -23.892 30.393  1 29.879 ? 1008 HOH A O   1 
HETATM 8753 O  O   . HOH G 4 .   ? -12.473 9.915   55.854  1 27.019 ? 1009 HOH A O   1 
HETATM 8754 O  O   . HOH G 4 .   ? 4.266   2.991   46.009  1 14.694 ? 1010 HOH A O   1 
HETATM 8755 O  O   . HOH G 4 .   ? 10.071  -12.656 55.178  1 31.893 ? 1011 HOH A O   1 
HETATM 8756 O  O   . HOH G 4 .   ? 51.362  -16.288 27.143  1 36.394 ? 1012 HOH A O   1 
HETATM 8757 O  O   . HOH G 4 .   ? 6.876   -8.922  58.124  1 20.248 ? 1013 HOH A O   1 
HETATM 8758 O  O   . HOH G 4 .   ? -19.802 -7.848  62.848  1 16.969 ? 1014 HOH A O   1 
HETATM 8759 O  O   . HOH G 4 .   ? -8.374  -16.896 51.155  1 11.218 ? 1015 HOH A O   1 
HETATM 8760 O  O   . HOH G 4 .   ? 4.108   -9.722  54.535  1 19.133 ? 1016 HOH A O   1 
HETATM 8761 O  O   . HOH G 4 .   ? 3.672   0.746   47.403  1 13.814 ? 1017 HOH A O   1 
HETATM 8762 O  O   . HOH G 4 .   ? -1.516  -5.232  35.023  1 28.077 ? 1018 HOH A O   1 
HETATM 8763 O  O   . HOH G 4 .   ? 8.47    -19.99  30.263  1 26.447 ? 1019 HOH A O   1 
HETATM 8764 O  O   . HOH G 4 .   ? -5.24   11.245  56.83   1 27.753 ? 1020 HOH A O   1 
HETATM 8765 O  O   . HOH G 4 .   ? -5.657  7.926   69.278  1 34.826 ? 1021 HOH A O   1 
HETATM 8766 O  O   . HOH G 4 .   ? -11.104 -31     49.295  1 26.735 ? 1022 HOH A O   1 
HETATM 8767 O  O   . HOH G 4 .   ? -18.938 -14.714 68.203  1 21.854 ? 1023 HOH A O   1 
HETATM 8768 O  O   . HOH G 4 .   ? 28.593  -3.356  44.332  1 36.151 ? 1024 HOH A O   1 
HETATM 8769 O  O   . HOH G 4 .   ? -5.753  10.94   54.787  1 25.726 ? 1025 HOH A O   1 
HETATM 8770 O  O   . HOH G 4 .   ? 57.46   -20.597 17.532  1 48.311 ? 1026 HOH A O   1 
HETATM 8771 O  O   . HOH G 4 .   ? 9.692   -23.524 56.757  1 18.538 ? 1027 HOH A O   1 
HETATM 8772 O  O   . HOH G 4 .   ? 8.986   16.023  56.648  1 36.005 ? 1028 HOH A O   1 
HETATM 8773 O  O   . HOH G 4 .   ? -9.654  6.14    48.24   1 22.96  ? 1029 HOH A O   1 
HETATM 8774 O  O   . HOH G 4 .   ? -2.937  -18.441 47.68   1 9.905  ? 1030 HOH A O   1 
HETATM 8775 O  O   . HOH G 4 .   ? -26.37  -10.334 51.756  1 32.936 ? 1031 HOH A O   1 
HETATM 8776 O  O   . HOH G 4 .   ? 11.22   -19.324 55.653  1 21.079 ? 1032 HOH A O   1 
HETATM 8777 O  O   . HOH G 4 .   ? -1.063  -14.91  29.246  1 11.588 ? 1033 HOH A O   1 
HETATM 8778 O  O   . HOH G 4 .   ? 19.85   -26.936 50.196  1 29.384 ? 1034 HOH A O   1 
HETATM 8779 O  O   . HOH G 4 .   ? -28.921 -11.748 46.663  1 35.924 ? 1035 HOH A O   1 
HETATM 8780 O  O   . HOH G 4 .   ? -15.612 -14.315 54.615  1 15.032 ? 1036 HOH A O   1 
HETATM 8781 O  O   . HOH G 4 .   ? -26.866 -13.975 45.983  1 19.505 ? 1037 HOH A O   1 
HETATM 8782 O  O   . HOH G 4 .   ? 3.253   2.377   72.869  1 37.923 ? 1038 HOH A O   1 
HETATM 8783 O  O   . HOH G 4 .   ? 12.157  -23.216 53.712  1 17.229 ? 1039 HOH A O   1 
HETATM 8784 O  O   . HOH G 4 .   ? 13.563  10.67   60.662  1 27.276 ? 1040 HOH A O   1 
HETATM 8785 O  O   . HOH G 4 .   ? -4.508  5.728   37.278  1 28.047 ? 1041 HOH A O   1 
HETATM 8786 O  O   . HOH G 4 .   ? -30.228 3.721   47.848  1 26.384 ? 1042 HOH A O   1 
HETATM 8787 O  O   . HOH G 4 .   ? -15.973 -12.347 78.47   1 51.522 ? 1043 HOH A O   1 
HETATM 8788 O  O   . HOH G 4 .   ? -1.243  1.858   25.056  1 36.706 ? 1044 HOH A O   1 
HETATM 8789 O  O   . HOH G 4 .   ? 32.389  -10.341 45.764  1 40.198 ? 1045 HOH A O   1 
HETATM 8790 O  O   . HOH G 4 .   ? 7.683   -27.808 36.28   1 24.956 ? 1046 HOH A O   1 
HETATM 8791 O  O   . HOH G 4 .   ? -14.553 5.179   58.503  1 27.645 ? 1047 HOH A O   1 
HETATM 8792 O  O   . HOH G 4 .   ? 2.184   -27.185 66.194  1 24.784 ? 1048 HOH A O   1 
HETATM 8793 O  O   . HOH G 4 .   ? 33.274  -26.702 22.959  1 31.134 ? 1049 HOH A O   1 
HETATM 8794 O  O   . HOH G 4 .   ? 50.135  -14.472 15.92   1 24.466 ? 1050 HOH A O   1 
HETATM 8795 O  O   . HOH G 4 .   ? 38.925  -25.022 27.5    1 24.245 ? 1051 HOH A O   1 
HETATM 8796 O  O   . HOH G 4 .   ? 22.141  8.286   49.826  1 28.939 ? 1052 HOH A O   1 
HETATM 8797 O  O   . HOH G 4 .   ? 9.529   -16.155 58.034  1 22.93  ? 1053 HOH A O   1 
HETATM 8798 O  O   . HOH G 4 .   ? 15.082  4.883   68.657  1 42.207 ? 1054 HOH A O   1 
HETATM 8799 O  O   . HOH G 4 .   ? 10.405  -15.749 69.091  1 23.648 ? 1055 HOH A O   1 
HETATM 8800 O  O   . HOH G 4 .   ? -22.392 -26.31  70.15   1 41.82  ? 1056 HOH A O   1 
HETATM 8801 O  O   . HOH G 4 .   ? 7.13    -5.718  35.578  1 25.027 ? 1057 HOH A O   1 
HETATM 8802 O  O   . HOH G 4 .   ? 10.53   9.826   66.971  1 29.465 ? 1058 HOH A O   1 
HETATM 8803 O  O   . HOH G 4 .   ? 18.423  -20.121 37.424  1 24.256 ? 1059 HOH A O   1 
HETATM 8804 O  O   . HOH G 4 .   ? 9.493   -19.782 58.818  1 40.834 ? 1060 HOH A O   1 
HETATM 8805 O  O   . HOH G 4 .   ? -18.597 -20.649 65.067  1 51.523 ? 1061 HOH A O   1 
HETATM 8806 O  O   . HOH G 4 .   ? -3.108  -2.433  17.629  1 37.48  ? 1062 HOH A O   1 
HETATM 8807 O  O   . HOH G 4 .   ? -9.387  7.172   63.886  1 36.119 ? 1063 HOH A O   1 
HETATM 8808 O  O   . HOH G 4 .   ? -18.439 -21.033 62.587  1 21.426 ? 1064 HOH A O   1 
HETATM 8809 O  O   . HOH G 4 .   ? -5.572  -28.805 44.431  1 12.068 ? 1065 HOH A O   1 
HETATM 8810 O  O   . HOH G 4 .   ? 3.126   -0.759  74.265  1 34.971 ? 1066 HOH A O   1 
HETATM 8811 O  O   . HOH G 4 .   ? 1.003   15.811  55.023  1 29.621 ? 1067 HOH A O   1 
HETATM 8812 O  O   . HOH G 4 .   ? 13.998  -15.526 29.484  1 32.864 ? 1068 HOH A O   1 
HETATM 8813 O  O   . HOH G 4 .   ? 1.425   2.228   26.556  1 40.614 ? 1069 HOH A O   1 
HETATM 8814 O  O   . HOH G 4 .   ? 4.106   -12.302 54.76   1 31.09  ? 1070 HOH A O   1 
HETATM 8815 O  O   . HOH G 4 .   ? 9.473   -17.439 30.095  1 22.849 ? 1071 HOH A O   1 
HETATM 8816 O  O   . HOH G 4 .   ? -18.345 -12.593 29.609  1 26.118 ? 1072 HOH A O   1 
HETATM 8817 O  O   . HOH G 4 .   ? -20.425 -22.549 66.792  1 39.976 ? 1073 HOH A O   1 
HETATM 8818 O  O   . HOH G 4 .   ? -20.473 -13.362 74.906  1 42.38  ? 1074 HOH A O   1 
HETATM 8819 O  O   . HOH G 4 .   ? 25.27   6.808   52.483  1 41.793 ? 1075 HOH A O   1 
HETATM 8820 O  O   . HOH G 4 .   ? 9.558   4.848   36.896  1 26.725 ? 1076 HOH A O   1 
HETATM 8821 O  O   . HOH G 4 .   ? -17.037 3.077   29.146  1 65.493 ? 1077 HOH A O   1 
HETATM 8822 O  O   . HOH G 4 .   ? 6.396   1.549   36.431  1 43.587 ? 1078 HOH A O   1 
HETATM 8823 O  O   . HOH G 4 .   ? 11.367  13.272  54.844  1 21.493 ? 1079 HOH A O   1 
HETATM 8824 O  O   . HOH G 4 .   ? 19.481  -14.562 69.427  1 41.033 ? 1080 HOH A O   1 
HETATM 8825 O  O   . HOH G 4 .   ? 38.774  -22.679 30.451  1 48.891 ? 1081 HOH A O   1 
HETATM 8826 O  O   . HOH G 4 .   ? 29.864  3.605   48.972  1 28.844 ? 1082 HOH A O   1 
HETATM 8827 O  O   . HOH G 4 .   ? -32.489 3.149   52.181  1 51.704 ? 1083 HOH A O   1 
HETATM 8828 O  O   . HOH G 4 .   ? 23.014  -28.229 42.508  1 38.647 ? 1084 HOH A O   1 
HETATM 8829 O  O   . HOH G 4 .   ? 8.859   6.149   16.312  1 25.962 ? 1085 HOH A O   1 
HETATM 8830 O  O   . HOH G 4 .   ? -1.37   10.174  20.755  1 43.533 ? 1086 HOH A O   1 
HETATM 8831 O  O   . HOH G 4 .   ? -3.642  -14.005 16.861  1 41.776 ? 1087 HOH A O   1 
HETATM 8832 O  O   . HOH G 4 .   ? 1.731   -24.265 70.601  1 40.632 ? 1088 HOH A O   1 
HETATM 8833 O  O   . HOH G 4 .   ? -6.121  4.643   39.075  1 22.508 ? 1089 HOH A O   1 
HETATM 8834 O  O   . HOH G 4 .   ? -16.96  -19.257 63.655  1 42.72  ? 1090 HOH A O   1 
HETATM 8835 O  O   . HOH G 4 .   ? -8.441  14.026  51.262  1 42.38  ? 1091 HOH A O   1 
HETATM 8836 O  O   . HOH G 4 .   ? 34.568  -28.701 23.239  1 39.78  ? 1092 HOH A O   1 
HETATM 8837 O  O   . HOH G 4 .   ? 1.597   -22.189 69.134  1 41.605 ? 1093 HOH A O   1 
HETATM 8838 O  O   . HOH G 4 .   ? 18.992  -30.244 41.047  1 52.631 ? 1094 HOH A O   1 
HETATM 8839 O  O   . HOH G 4 .   ? 2.174   -7.887  54.499  1 12.084 ? 1095 HOH A O   1 
HETATM 8840 O  O   . HOH G 4 .   ? 11.658  -21.736 64.591  1 40.622 ? 1096 HOH A O   1 
HETATM 8841 O  O   . HOH G 4 .   ? 27.435  -14.504 53.85   1 46.07  ? 1097 HOH A O   1 
HETATM 8842 O  O   . HOH G 4 .   ? -22.786 -4.994  49.746  1 26.035 ? 1098 HOH A O   1 
HETATM 8843 O  O   . HOH G 4 .   ? -12.085 -7.14   32.608  1 20.637 ? 1099 HOH A O   1 
HETATM 8844 O  O   . HOH G 4 .   ? 1.847   19.187  52.005  1 38.13  ? 1100 HOH A O   1 
HETATM 8845 O  O   . HOH G 4 .   ? -4.95   -23.907 26.441  1 26.882 ? 1101 HOH A O   1 
HETATM 8846 O  O   . HOH G 4 .   ? 15.513  15.848  49.395  1 33.046 ? 1102 HOH A O   1 
HETATM 8847 O  O   . HOH G 4 .   ? -14.785 8.884   45.293  1 38.105 ? 1103 HOH A O   1 
HETATM 8848 O  O   . HOH G 4 .   ? 24.417  -20.232 57.798  1 43.851 ? 1104 HOH A O   1 
HETATM 8849 O  O   . HOH G 4 .   ? 13.07   -19.545 68.254  1 39.878 ? 1105 HOH A O   1 
HETATM 8850 O  O   . HOH G 4 .   ? 4.422   18.718  49.419  1 41.802 ? 1106 HOH A O   1 
HETATM 8851 O  O   . HOH G 4 .   ? -18.501 -24.888 59.712  1 26.542 ? 1107 HOH A O   1 
HETATM 8852 O  O   . HOH G 4 .   ? 11.953  -16.875 31.403  1 27.615 ? 1108 HOH A O   1 
HETATM 8853 O  O   . HOH G 4 .   ? 25.986  -16.681 39.645  1 38.339 ? 1109 HOH A O   1 
HETATM 8854 O  O   . HOH G 4 .   ? 15.764  -29.174 42.056  1 42.111 ? 1110 HOH A O   1 
HETATM 8855 O  O   . HOH G 4 .   ? 14.055  19.254  47.321  1 34.206 ? 1111 HOH A O   1 
HETATM 8856 O  O   . HOH G 4 .   ? -5.224  -22.276 22.744  1 32.784 ? 1112 HOH A O   1 
HETATM 8857 O  O   . HOH G 4 .   ? -23.858 -5.103  31.880  1 37.527 ? 1113 HOH A O   1 
HETATM 8858 O  O   . HOH G 4 .   ? 35.404  -27.845 32.229  1 40.818 ? 1114 HOH A O   1 
HETATM 8859 O  O   . HOH G 4 .   ? 1.945   -14.43  75.137  1 30.087 ? 1115 HOH A O   1 
HETATM 8860 O  O   . HOH G 4 .   ? -22.052 -5.028  75.314  1 44.101 ? 1116 HOH A O   1 
HETATM 8861 O  O   . HOH G 4 .   ? 22.424  8.075   36.857  1 43.109 ? 1117 HOH A O   1 
HETATM 8862 O  O   . HOH G 4 .   ? 29.98   -15.056 53.553  1 40.764 ? 1118 HOH A O   1 
HETATM 8863 O  O   . HOH G 4 .   ? 13.831  -24.688 34.408  1 37.848 ? 1119 HOH A O   1 
HETATM 8864 O  O   . HOH G 4 .   ? -29.846 -21.177 38.911  1 34.253 ? 1120 HOH A O   1 
HETATM 8865 O  O   . HOH G 4 .   ? -20.232 -2.121  41.324  1 25.963 ? 1121 HOH A O   1 
HETATM 8866 O  O   . HOH G 4 .   ? -12.863 -29.531 63.784  1 30.113 ? 1122 HOH A O   1 
HETATM 8867 O  O   . HOH G 4 .   ? 2.093   11.211  23.229  1 53.016 ? 1123 HOH A O   1 
HETATM 8868 O  O   . HOH G 4 .   ? -20.285 -19.666 70.12   1 44.799 ? 1124 HOH A O   1 
HETATM 8869 O  O   . HOH G 4 .   ? 11.972  -20.557 28.761  1 38.909 ? 1125 HOH A O   1 
HETATM 8870 O  O   . HOH G 4 .   ? -20.959 0.616   62.488  1 40.962 ? 1126 HOH A O   1 
HETATM 8871 O  O   . HOH G 4 .   ? 11.801  -22.01  55.997  1 19.005 ? 1127 HOH A O   1 
HETATM 8872 O  O   . HOH G 4 .   ? -23.041 -20.027 50.272  1 23.92  ? 1128 HOH A O   1 
HETATM 8873 O  O   . HOH G 4 .   ? 57.092  -18.413 15.986  1 49.912 ? 1129 HOH A O   1 
HETATM 8874 O  O   . HOH G 4 .   ? -18.106 -27.23  60.878  1 23.65  ? 1130 HOH A O   1 
HETATM 8875 O  O   . HOH G 4 .   ? 16.154  12.168  52.098  1 27.405 ? 1131 HOH A O   1 
HETATM 8876 O  O   . HOH G 4 .   ? 30.164  -14.373 41.3    1 33.679 ? 1132 HOH A O   1 
HETATM 8877 O  O   . HOH G 4 .   ? 16.216  -26.37  37.816  1 36.613 ? 1133 HOH A O   1 
HETATM 8878 O  O   . HOH G 4 .   ? -4.745  -14.902 78.163  1 35.519 ? 1134 HOH A O   1 
HETATM 8879 O  O   . HOH G 4 .   ? -8.538  -20.063 74.066  1 28.364 ? 1135 HOH A O   1 
HETATM 8880 O  O   . HOH G 4 .   ? 31.152  -30.359 24.773  1 44.203 ? 1136 HOH A O   1 
HETATM 8881 O  O   . HOH G 4 .   ? -16.651 5.894   41.515  1 35.908 ? 1137 HOH A O   1 
HETATM 8882 O  O   . HOH G 4 .   ? -13.823 -0.323  75.918  1 27.573 ? 1138 HOH A O   1 
HETATM 8883 O  O   . HOH G 4 .   ? 12.378  -9.348  72.711  1 38.711 ? 1139 HOH A O   1 
HETATM 8884 O  O   . HOH G 4 .   ? -23.134 -21.314 45.982  1 18.209 ? 1140 HOH A O   1 
HETATM 8885 O  O   . HOH G 4 .   ? -12.63  10.596  45.253  1 39.66  ? 1141 HOH A O   1 
HETATM 8886 O  O   . HOH G 4 .   ? 20.905  1.882   65.6    1 34.198 ? 1142 HOH A O   1 
HETATM 8887 O  O   . HOH G 4 .   ? 11.7    -17.029 54.73   1 31.988 ? 1143 HOH A O   1 
HETATM 8888 O  O   . HOH G 4 .   ? -9.647  -2.985  80.366  1 36.812 ? 1144 HOH A O   1 
HETATM 8889 O  O   . HOH G 4 .   ? 4.456   -12.239 57.119  1 26.109 ? 1145 HOH A O   1 
HETATM 8890 O  O   . HOH G 4 .   ? 16.526  -26.945 52.026  1 44.254 ? 1146 HOH A O   1 
HETATM 8891 O  O   . HOH G 4 .   ? -20.057 -3.409  37.391  1 27.166 ? 1147 HOH A O   1 
HETATM 8892 O  O   . HOH G 4 .   ? 4.114   -9.839  57.28   1 28.145 ? 1148 HOH A O   1 
HETATM 8893 O  O   . HOH G 4 .   ? 57.022  -23.339 22.579  1 39.359 ? 1149 HOH A O   1 
HETATM 8894 O  O   . HOH G 4 .   ? 2.798   -26.936 68.593  1 34.868 ? 1150 HOH A O   1 
HETATM 8895 O  O   . HOH G 4 .   ? 13.806  -25.812 45.371  1 22.736 ? 1151 HOH A O   1 
HETATM 8896 O  O   . HOH G 4 .   ? -30.516 -17.3   45.506  1 31.981 ? 1152 HOH A O   1 
HETATM 8897 O  O   . HOH G 4 .   ? -13.373 -4.747  73.994  1 23.613 ? 1153 HOH A O   1 
HETATM 8898 O  O   . HOH G 4 .   ? -20.732 -26.531 57.355  1 41.057 ? 1154 HOH A O   1 
HETATM 8899 O  O   . HOH G 4 .   ? -0.415  -30.571 67.657  1 43.481 ? 1155 HOH A O   1 
HETATM 8900 O  O   . HOH G 4 .   ? -24.524 -17.435 47.695  1 24.587 ? 1156 HOH A O   1 
HETATM 8901 O  O   . HOH G 4 .   ? -14.087 -29.775 71.685  1 43.96  ? 1157 HOH A O   1 
HETATM 8902 O  O   . HOH G 4 .   ? -11.754 3.383   74.848  1 53.425 ? 1158 HOH A O   1 
HETATM 8903 O  O   . HOH G 4 .   ? -9.789  -3.384  75.981  1 25.652 ? 1159 HOH A O   1 
HETATM 8904 O  O   . HOH G 4 .   ? -17.4   1.926   39.638  1 44.808 ? 1160 HOH A O   1 
HETATM 8905 O  O   . HOH G 4 .   ? 23.667  -15.828 43.78   1 26.032 ? 1161 HOH A O   1 
HETATM 8906 O  O   . HOH G 4 .   ? -29.509 -5.539  45.589  1 44.646 ? 1162 HOH A O   1 
HETATM 8907 O  O   . HOH G 4 .   ? -8.031  0.896   74.433  1 23.187 ? 1163 HOH A O   1 
HETATM 8908 O  O   . HOH G 4 .   ? -13.702 6.094   41.714  1 31.776 ? 1164 HOH A O   1 
HETATM 8909 O  O   . HOH G 4 .   ? 6.038   11.476  37.394  1 45.367 ? 1165 HOH A O   1 
HETATM 8910 O  O   . HOH G 4 .   ? 5.048   -31.651 36.43   1 26.79  ? 1166 HOH A O   1 
HETATM 8911 O  O   . HOH G 4 .   ? -2.381  -6.582  20.64   1 39.506 ? 1167 HOH A O   1 
HETATM 8912 O  O   . HOH G 4 .   ? -20.672 -20.35  67.81   1 48.729 ? 1168 HOH A O   1 
HETATM 8913 O  O   . HOH G 4 .   ? 28.205  -28.621 22.677  1 30.334 ? 1169 HOH A O   1 
HETATM 8914 O  O   . HOH G 4 .   ? -30.386 -11.14  43.979  1 35.75  ? 1170 HOH A O   1 
HETATM 8915 O  O   . HOH G 4 .   ? 16.435  -13.147 68.41   1 44.401 ? 1171 HOH A O   1 
HETATM 8916 O  O   . HOH G 4 .   ? 24.249  4.656   56.764  1 29.202 ? 1172 HOH A O   1 
HETATM 8917 O  O   . HOH G 4 .   ? -23.688 -4.521  39.921  1 40.229 ? 1173 HOH A O   1 
HETATM 8918 O  O   . HOH G 4 .   ? 6.908   23.009  20.571  1 42.731 ? 1174 HOH A O   1 
HETATM 8919 O  O   . HOH G 4 .   ? 56.628  -8.717  14.075  1 33.692 ? 1175 HOH A O   1 
HETATM 8920 O  O   . HOH G 4 .   ? 37.069  -29.764 35.939  1 53.649 ? 1176 HOH A O   1 
HETATM 8921 O  O   . HOH G 4 .   ? -14.866 5.277   74.033  1 43.896 ? 1177 HOH A O   1 
HETATM 8922 O  O   . HOH G 4 .   ? -9.159  2.452   18.353  1 39.965 ? 1178 HOH A O   1 
HETATM 8923 O  O   . HOH G 4 .   ? 10.248  -28.394 36.08   1 29.164 ? 1179 HOH A O   1 
HETATM 8924 O  O   . HOH G 4 .   ? -10.671 9.974   43.473  1 41.69  ? 1180 HOH A O   1 
HETATM 8925 O  O   . HOH G 4 .   ? -14.9   -32.334 70.651  1 41.098 ? 1181 HOH A O   1 
HETATM 8926 O  O   . HOH G 4 .   ? 15.051  -20.109 65.678  1 55.472 ? 1182 HOH A O   1 
HETATM 8927 O  O   . HOH G 4 .   ? -1.522  4.881   25.595  1 35.54  ? 1183 HOH A O   1 
HETATM 8928 O  O   . HOH G 4 .   ? 13.42   -23.181 57.872  1 27.209 ? 1184 HOH A O   1 
HETATM 8929 O  O   . HOH G 4 .   ? -31.381 -1.819  42.78   1 45.906 ? 1185 HOH A O   1 
HETATM 8930 O  O   . HOH G 4 .   ? 57.721  -10.259 10.752  1 54.871 ? 1186 HOH A O   1 
HETATM 8931 O  O   . HOH H 4 .   ? 4.257   2.238   26.449  1 32.007 ? 701  HOH B O   1 
HETATM 8932 O  O   . HOH H 4 .   ? 17.179  -7.707  -3.905  1 49.341 ? 702  HOH B O   1 
HETATM 8933 O  O   . HOH H 4 .   ? 25.414  16.758  13.183  1 20.935 ? 703  HOH B O   1 
HETATM 8934 O  O   . HOH H 4 .   ? 28.281  -7.492  27.18   1 42.865 ? 704  HOH B O   1 
HETATM 8935 O  O   . HOH H 4 .   ? 49.578  -9.98   31.328  1 46.037 ? 705  HOH B O   1 
HETATM 8936 O  O   . HOH H 4 .   ? 12.894  3.086   30.649  1 61.806 ? 706  HOH B O   1 
HETATM 8937 O  O   . HOH H 4 .   ? 28.034  8.917   -4.158  1 40.374 ? 707  HOH B O   1 
HETATM 8938 O  O   . HOH H 4 .   ? 41.158  9.99    20.146  1 29.295 ? 708  HOH B O   1 
HETATM 8939 O  O   . HOH H 4 .   ? 51.533  5.864   19.018  1 36.888 ? 709  HOH B O   1 
HETATM 8940 O  O   . HOH H 4 .   ? 23.438  -11.769 -7.249  1 35.544 ? 710  HOH B O   1 
HETATM 8941 O  O   . HOH H 4 .   ? 17.347  -6.321  22.33   1 42.044 ? 711  HOH B O   1 
HETATM 8942 O  O   . HOH H 4 .   ? 0.392   -8.624  0.332   1 25.695 ? 712  HOH B O   1 
HETATM 8943 O  O   . HOH H 4 .   ? 48.079  7.954   18.836  1 32.336 ? 713  HOH B O   1 
HETATM 8944 O  O   . HOH H 4 .   ? 31.722  4.51    -13.828 1 37.935 ? 714  HOH B O   1 
HETATM 8945 O  O   . HOH H 4 .   ? 43.211  -4.563  36.311  1 27.269 ? 715  HOH B O   1 
HETATM 8946 O  O   . HOH H 4 .   ? 35.12   -4.534  15.711  1 18.492 ? 716  HOH B O   1 
HETATM 8947 O  O   . HOH H 4 .   ? 33.031  -20.894 10.701  1 17.121 ? 717  HOH B O   1 
HETATM 8948 O  O   . HOH H 4 .   ? 13.521  -16.257 10.975  1 23.761 ? 718  HOH B O   1 
HETATM 8949 O  O   . HOH H 4 .   ? 28.853  2.133   -15.066 1 33.699 ? 719  HOH B O   1 
HETATM 8950 O  O   . HOH H 4 .   ? 31.167  -8.449  -15.987 1 21.689 ? 720  HOH B O   1 
HETATM 8951 O  O   . HOH H 4 .   ? 13.176  -15.273 10.698  1 18.973 ? 721  HOH B O   1 
HETATM 8952 O  O   . HOH H 4 .   ? 29.054  2.033   -7.204  1 39.629 ? 722  HOH B O   1 
HETATM 8953 O  O   . HOH H 4 .   ? 41.926  -6.178  -14.022 1 29.511 ? 723  HOH B O   1 
HETATM 8954 O  O   . HOH H 4 .   ? -1.274  0.592   11.006  1 34.386 ? 724  HOH B O   1 
HETATM 8955 O  O   . HOH H 4 .   ? 45.568  -18.551 -11.784 1 31.611 ? 725  HOH B O   1 
HETATM 8956 O  O   . HOH H 4 .   ? 24.973  -17.511 28.985  1 16.845 ? 726  HOH B O   1 
HETATM 8957 O  O   . HOH H 4 .   ? 28.264  -26.047 -4.025  1 28.636 ? 727  HOH B O   1 
HETATM 8958 O  O   . HOH H 4 .   ? 1.374   -0.761  4.33    1 37.76  ? 728  HOH B O   1 
HETATM 8959 O  O   . HOH H 4 .   ? 28.604  16.037  3.451   1 29.791 ? 729  HOH B O   1 
HETATM 8960 O  O   . HOH H 4 .   ? 26.855  1.893   38.746  1 30.679 ? 730  HOH B O   1 
HETATM 8961 O  O   . HOH H 4 .   ? 15.771  16.843  14.363  1 41.027 ? 731  HOH B O   1 
HETATM 8962 O  O   . HOH H 4 .   ? 18.405  10.906  -5.677  1 30.668 ? 732  HOH B O   1 
HETATM 8963 O  O   . HOH H 4 .   ? -25.892 -21.614 45.066  1 29.594 ? 733  HOH B O   1 
HETATM 8964 O  O   . HOH H 4 .   ? 8.066   -18.997 14.564  1 21.084 ? 734  HOH B O   1 
HETATM 8965 O  O   . HOH H 4 .   ? 41.246  5.633   22.526  1 19.522 ? 735  HOH B O   1 
HETATM 8966 O  O   . HOH H 4 .   ? 33.849  -25.069 5.382   1 34.077 ? 736  HOH B O   1 
HETATM 8967 O  O   . HOH H 4 .   ? 9.52    -27.588 12.496  1 25.733 ? 737  HOH B O   1 
HETATM 8968 O  O   . HOH H 4 .   ? 47.193  2.709   26.206  1 27.465 ? 738  HOH B O   1 
HETATM 8969 O  O   . HOH H 4 .   ? 34.121  -8.258  27.562  1 13.807 ? 739  HOH B O   1 
HETATM 8970 O  O   . HOH H 4 .   ? 23.47   -15.712 27.355  1 25.07  ? 740  HOH B O   1 
HETATM 8971 O  O   . HOH H 4 .   ? 26.146  12.474  -8.788  1 40.868 ? 741  HOH B O   1 
HETATM 8972 O  O   . HOH H 4 .   ? 33.375  -9.488  40.899  1 37.085 ? 742  HOH B O   1 
HETATM 8973 O  O   . HOH H 4 .   ? 15.418  -25.042 14.737  1 26.147 ? 743  HOH B O   1 
HETATM 8974 O  O   . HOH H 4 .   ? 39.072  -18.941 23.331  1 17.357 ? 744  HOH B O   1 
HETATM 8975 O  O   . HOH H 4 .   ? 10.214  -1.379  31.389  1 36.409 ? 745  HOH B O   1 
HETATM 8976 O  O   . HOH H 4 .   ? -1.849  9.531   8.225   1 35.804 ? 746  HOH B O   1 
HETATM 8977 O  O   . HOH H 4 .   ? 7.427   6.183   -1.028  1 24.437 ? 747  HOH B O   1 
HETATM 8978 O  O   . HOH H 4 .   ? 0.579   -32.097 32.56   1 24.625 ? 748  HOH B O   1 
HETATM 8979 O  O   . HOH H 4 .   ? 34.167  -13.131 15.921  1 13.73  ? 749  HOH B O   1 
HETATM 8980 O  O   . HOH H 4 .   ? 27.682  -22.937 -4.835  1 27.716 ? 750  HOH B O   1 
HETATM 8981 O  O   . HOH H 4 .   ? 13.832  -0.42   -6.521  1 29.615 ? 751  HOH B O   1 
HETATM 8982 O  O   . HOH H 4 .   ? 51.375  -12.19  -1.27   1 31.224 ? 752  HOH B O   1 
HETATM 8983 O  O   . HOH H 4 .   ? 29.116  9.741   24.483  1 22.789 ? 753  HOH B O   1 
HETATM 8984 O  O   . HOH H 4 .   ? 36.706  -8.614  -15.124 1 21.447 ? 754  HOH B O   1 
HETATM 8985 O  O   . HOH H 4 .   ? 43.205  -11.06  -12.474 1 22.915 ? 755  HOH B O   1 
HETATM 8986 O  O   . HOH H 4 .   ? 42.859  -9.002  17.129  1 18.91  ? 756  HOH B O   1 
HETATM 8987 O  O   . HOH H 4 .   ? 18.164  -4.975  3.828   1 17.678 ? 757  HOH B O   1 
HETATM 8988 O  O   . HOH H 4 .   ? 52.38   -3.66   10.755  1 26.892 ? 758  HOH B O   1 
HETATM 8989 O  O   . HOH H 4 .   ? 17.173  19.751  1.684   1 41.982 ? 759  HOH B O   1 
HETATM 8990 O  O   . HOH H 4 .   ? 44.131  13.485  -8.483  1 36.514 ? 760  HOH B O   1 
HETATM 8991 O  O   . HOH H 4 .   ? 4.675   3.668   4.98    1 26.697 ? 761  HOH B O   1 
HETATM 8992 O  O   . HOH H 4 .   ? 44.187  1.985   -8.906  1 16.747 ? 762  HOH B O   1 
HETATM 8993 O  O   . HOH H 4 .   ? -1.551  -8.132  10.312  1 34.297 ? 763  HOH B O   1 
HETATM 8994 O  O   . HOH H 4 .   ? 43.515  1.939   -12.336 1 22.191 ? 764  HOH B O   1 
HETATM 8995 O  O   . HOH H 4 .   ? 9.304   -27.64  16.44   1 34.073 ? 765  HOH B O   1 
HETATM 8996 O  O   . HOH H 4 .   ? 6.76    -17.382 20.634  1 22.165 ? 766  HOH B O   1 
HETATM 8997 O  O   . HOH H 4 .   ? 26.995  22.041  14.005  1 31.124 ? 767  HOH B O   1 
HETATM 8998 O  O   . HOH H 4 .   ? 19.811  -22.798 12.845  1 20.127 ? 768  HOH B O   1 
HETATM 8999 O  O   . HOH H 4 .   ? 11.53   -23.984 26.798  1 31.85  ? 769  HOH B O   1 
HETATM 9000 O  O   . HOH H 4 .   ? 12.715  17.254  7.144   1 43.227 ? 770  HOH B O   1 
HETATM 9001 O  O   . HOH H 4 .   ? 26.433  -26.85  21.178  1 26.594 ? 771  HOH B O   1 
HETATM 9002 O  O   . HOH H 4 .   ? 27.784  -22.493 28.142  1 24.334 ? 772  HOH B O   1 
HETATM 9003 O  O   . HOH H 4 .   ? 15.066  -8.608  -0.01   1 20.332 ? 773  HOH B O   1 
HETATM 9004 O  O   . HOH H 4 .   ? 48.609  -15.533 3.032   1 20.027 ? 774  HOH B O   1 
HETATM 9005 O  O   . HOH H 4 .   ? 29.413  0.222   41.084  1 38.673 ? 775  HOH B O   1 
HETATM 9006 O  O   . HOH H 4 .   ? 24.111  11.245  19.627  1 35.131 ? 776  HOH B O   1 
HETATM 9007 O  O   . HOH H 4 .   ? 22.415  9.18    -8.331  1 32.341 ? 777  HOH B O   1 
HETATM 9008 O  O   . HOH H 4 .   ? 14.52   18.142  5.743   1 29.646 ? 778  HOH B O   1 
HETATM 9009 O  O   . HOH H 4 .   ? 36.553  16.339  6.153   1 19.746 ? 779  HOH B O   1 
HETATM 9010 O  O   . HOH H 4 .   ? 23.614  10.311  49.322  1 35.598 ? 780  HOH B O   1 
HETATM 9011 O  O   . HOH H 4 .   ? -0.11   -2.357  8.229   1 31.795 ? 781  HOH B O   1 
HETATM 9012 O  O   . HOH H 4 .   ? 10.362  7.19    14.202  1 22.446 ? 782  HOH B O   1 
HETATM 9013 O  O   . HOH H 4 .   ? 18.122  5.424   30.672  1 53.363 ? 783  HOH B O   1 
HETATM 9014 O  O   . HOH H 4 .   ? 26.736  -7.16   -12.675 1 23.839 ? 784  HOH B O   1 
HETATM 9015 O  O   . HOH H 4 .   ? 18.712  -3.277  -3.899  1 17.541 ? 785  HOH B O   1 
HETATM 9016 O  O   . HOH H 4 .   ? -1.372  -3.834  16.86   1 33.004 ? 786  HOH B O   1 
HETATM 9017 O  O   . HOH H 4 .   ? 18.317  -23.844 22.821  1 17.247 ? 787  HOH B O   1 
HETATM 9018 O  O   . HOH H 4 .   ? 52.459  11.559  19.228  1 45.742 ? 788  HOH B O   1 
HETATM 9019 O  O   . HOH H 4 .   ? 8.352   17.235  10.896  1 39.944 ? 789  HOH B O   1 
HETATM 9020 O  O   . HOH H 4 .   ? 35.55   -14.916 22.377  1 14.849 ? 790  HOH B O   1 
HETATM 9021 O  O   . HOH H 4 .   ? 8.818   11.589  11.972  1 28.116 ? 791  HOH B O   1 
HETATM 9022 O  O   . HOH H 4 .   ? 36.793  5.111   26.891  1 26.831 ? 792  HOH B O   1 
HETATM 9023 O  O   . HOH H 4 .   ? 43.061  -0.976  20.196  1 11.214 ? 793  HOH B O   1 
HETATM 9024 O  O   . HOH H 4 .   ? 22.447  -19.366 0.688   1 22.373 ? 794  HOH B O   1 
HETATM 9025 O  O   . HOH H 4 .   ? 49.628  -3.061  -14.449 1 35.775 ? 795  HOH B O   1 
HETATM 9026 O  O   . HOH H 4 .   ? 49.35   -5.902  29.933  1 37.036 ? 796  HOH B O   1 
HETATM 9027 O  O   . HOH H 4 .   ? 21.636  -12.254 32.351  1 12.726 ? 797  HOH B O   1 
HETATM 9028 O  O   . HOH H 4 .   ? 34.251  -6.873  9.335   1 15.868 ? 798  HOH B O   1 
HETATM 9029 O  O   . HOH H 4 .   ? 28.855  -29.556 -0.332  1 58.23  ? 799  HOH B O   1 
HETATM 9030 O  O   . HOH H 4 .   ? 31.491  -11.116 24.282  1 12.894 ? 800  HOH B O   1 
HETATM 9031 O  O   . HOH H 4 .   ? 34.742  -5.849  36.087  1 17.415 ? 801  HOH B O   1 
HETATM 9032 O  O   . HOH H 4 .   ? 50.404  3.774   9.255   1 20.86  ? 802  HOH B O   1 
HETATM 9033 O  O   . HOH H 4 .   ? 28.845  9.476   5.003   1 16.451 ? 803  HOH B O   1 
HETATM 9034 O  O   . HOH H 4 .   ? 42.763  13.022  4.365   1 23.488 ? 804  HOH B O   1 
HETATM 9035 O  O   . HOH H 4 .   ? 7.366   0.489   -3.21   1 26.034 ? 805  HOH B O   1 
HETATM 9036 O  O   . HOH H 4 .   ? 34.106  -6.665  13.4    1 16.884 ? 806  HOH B O   1 
HETATM 9037 O  O   . HOH H 4 .   ? 20.384  -12.868 -8.704  1 20.75  ? 807  HOH B O   1 
HETATM 9038 O  O   . HOH H 4 .   ? 19.577  13.499  40.84   1 21.959 ? 808  HOH B O   1 
HETATM 9039 O  O   . HOH H 4 .   ? 38.764  -1.914  25.913  1 21.858 ? 809  HOH B O   1 
HETATM 9040 O  O   . HOH H 4 .   ? 10.161  4.193   -1.268  1 32.492 ? 810  HOH B O   1 
HETATM 9041 O  O   . HOH H 4 .   ? 37.422  2.589   36.286  1 35.764 ? 811  HOH B O   1 
HETATM 9042 O  O   . HOH H 4 .   ? 24.806  -3.358  2.542   1 15.024 ? 812  HOH B O   1 
HETATM 9043 O  O   . HOH H 4 .   ? 42.03   -13.562 15.513  1 17.704 ? 813  HOH B O   1 
HETATM 9044 O  O   . HOH H 4 .   ? 48.102  -18.246 -2.479  1 20.997 ? 814  HOH B O   1 
HETATM 9045 O  O   . HOH H 4 .   ? 3.87    -7.986  -3.543  1 28.208 ? 815  HOH B O   1 
HETATM 9046 O  O   . HOH H 4 .   ? 51.76   -3.309  8.092   1 18.883 ? 816  HOH B O   1 
HETATM 9047 O  O   . HOH H 4 .   ? 44.33   -12.849 13.989  1 12.329 ? 817  HOH B O   1 
HETATM 9048 O  O   . HOH H 4 .   ? -23.657 -21.377 38.664  1 14.472 ? 818  HOH B O   1 
HETATM 9049 O  O   . HOH H 4 .   ? 2.985   -10.312 10.302  1 26.669 ? 819  HOH B O   1 
HETATM 9050 O  O   . HOH H 4 .   ? 8.206   11.666  22.503  1 27.585 ? 820  HOH B O   1 
HETATM 9051 O  O   . HOH H 4 .   ? 20.912  5.231   17.767  1 14.655 ? 821  HOH B O   1 
HETATM 9052 O  O   . HOH H 4 .   ? 0.264   -4.66   4.772   1 34.039 ? 822  HOH B O   1 
HETATM 9053 O  O   . HOH H 4 .   ? 36.525  -6.392  29.721  1 19.468 ? 823  HOH B O   1 
HETATM 9054 O  O   . HOH H 4 .   ? 41.013  -9.402  11.35   1 17.991 ? 824  HOH B O   1 
HETATM 9055 O  O   . HOH H 4 .   ? 15.012  0.753   -8.927  1 25.707 ? 825  HOH B O   1 
HETATM 9056 O  O   . HOH H 4 .   ? 27.771  -3.54   3.895   1 12.086 ? 826  HOH B O   1 
HETATM 9057 O  O   . HOH H 4 .   ? 49.407  6.849   12.255  1 19.204 ? 827  HOH B O   1 
HETATM 9058 O  O   . HOH H 4 .   ? -20.128 -23.909 33.212  1 26.837 ? 828  HOH B O   1 
HETATM 9059 O  O   . HOH H 4 .   ? 34.409  -7.499  -15.091 1 20.159 ? 829  HOH B O   1 
HETATM 9060 O  O   . HOH H 4 .   ? 39.016  14.95   12.712  1 22.911 ? 830  HOH B O   1 
HETATM 9061 O  O   . HOH H 4 .   ? 27.811  -4.663  0.49    1 20.105 ? 831  HOH B O   1 
HETATM 9062 O  O   . HOH H 4 .   ? 17.866  -0.752  13.311  1 10.455 ? 832  HOH B O   1 
HETATM 9063 O  O   . HOH H 4 .   ? 49.675  -15.171 29.441  1 27.503 ? 833  HOH B O   1 
HETATM 9064 O  O   . HOH H 4 .   ? 11.313  10.615  21.42   1 26.839 ? 834  HOH B O   1 
HETATM 9065 O  O   . HOH H 4 .   ? 28.556  4.026   31.083  1 25.281 ? 835  HOH B O   1 
HETATM 9066 O  O   . HOH H 4 .   ? -4.951  -31.226 35.821  1 41.602 ? 836  HOH B O   1 
HETATM 9067 O  O   . HOH H 4 .   ? 26.922  -2.455  28.927  1 17.249 ? 837  HOH B O   1 
HETATM 9068 O  O   . HOH H 4 .   ? -10.351 -29.762 45.523  1 19.942 ? 838  HOH B O   1 
HETATM 9069 O  O   . HOH H 4 .   ? 30.628  24.14   12.142  1 33.761 ? 839  HOH B O   1 
HETATM 9070 O  O   . HOH H 4 .   ? 18.355  -10.838 -8.613  1 28.393 ? 840  HOH B O   1 
HETATM 9071 O  O   . HOH H 4 .   ? 30.081  7.447   -11.21  1 30.543 ? 841  HOH B O   1 
HETATM 9072 O  O   . HOH H 4 .   ? 22.645  14.894  -2.123  1 31.18  ? 842  HOH B O   1 
HETATM 9073 O  O   . HOH H 4 .   ? 36.566  -8.006  7.995   1 13.628 ? 843  HOH B O   1 
HETATM 9074 O  O   . HOH H 4 .   ? 23.008  -9.726  32.192  1 16.977 ? 844  HOH B O   1 
HETATM 9075 O  O   . HOH H 4 .   ? 30.495  17.507  17.759  1 35.835 ? 845  HOH B O   1 
HETATM 9076 O  O   . HOH H 4 .   ? 24.479  7.976   28.059  1 25.607 ? 846  HOH B O   1 
HETATM 9077 O  O   . HOH H 4 .   ? -10.257 -32.457 38.004  1 32.336 ? 847  HOH B O   1 
HETATM 9078 O  O   . HOH H 4 .   ? 23.838  -17.188 23.724  1 18.289 ? 848  HOH B O   1 
HETATM 9079 O  O   . HOH H 4 .   ? 21.787  1.921   26.161  1 15.152 ? 849  HOH B O   1 
HETATM 9080 O  O   . HOH H 4 .   ? 24.703  -6.452  -5.318  1 17.278 ? 850  HOH B O   1 
HETATM 9081 O  O   . HOH H 4 .   ? 23.634  17.439  5.426   1 32.967 ? 851  HOH B O   1 
HETATM 9082 O  O   . HOH H 4 .   ? 17.805  18.205  45.96   1 27.657 ? 852  HOH B O   1 
HETATM 9083 O  O   . HOH H 4 .   ? 2.222   -15.765 15.106  1 37.993 ? 853  HOH B O   1 
HETATM 9084 O  O   . HOH H 4 .   ? 7.086   8.548   12.408  1 22.773 ? 854  HOH B O   1 
HETATM 9085 O  O   . HOH H 4 .   ? 37.681  18.586  8.092   1 21.764 ? 855  HOH B O   1 
HETATM 9086 O  O   . HOH H 4 .   ? 23.272  8.192   15.476  1 18.077 ? 856  HOH B O   1 
HETATM 9087 O  O   . HOH H 4 .   ? 10.341  19.423  19.605  1 34.905 ? 857  HOH B O   1 
HETATM 9088 O  O   . HOH H 4 .   ? 38.791  -5.273  24.19   1 17.641 ? 858  HOH B O   1 
HETATM 9089 O  O   . HOH H 4 .   ? 5.632   -19.178 27.954  1 16.161 ? 859  HOH B O   1 
HETATM 9090 O  O   . HOH H 4 .   ? 19.91   -7.576  -11.346 1 27.828 ? 860  HOH B O   1 
HETATM 9091 O  O   . HOH H 4 .   ? 7.16    -8.58   3.86    1 22.253 ? 861  HOH B O   1 
HETATM 9092 O  O   . HOH H 4 .   ? 22.24   -11.626 0.36    1 30.153 ? 862  HOH B O   1 
HETATM 9093 O  O   . HOH H 4 .   ? 17.868  -21.588 26.051  1 26.438 ? 863  HOH B O   1 
HETATM 9094 O  O   . HOH H 4 .   ? 6.077   -14.593 -1.33   1 30.449 ? 864  HOH B O   1 
HETATM 9095 O  O   . HOH H 4 .   ? 3.447   -13.773 9.04    1 16.668 ? 865  HOH B O   1 
HETATM 9096 O  O   . HOH H 4 .   ? 51.414  -7.918  -1.312  1 31.136 ? 866  HOH B O   1 
HETATM 9097 O  O   . HOH H 4 .   ? 2.23    -21.333 11.002  1 37.438 ? 867  HOH B O   1 
HETATM 9098 O  O   . HOH H 4 .   ? 24.554  -10.679 7.134   1 19.662 ? 868  HOH B O   1 
HETATM 9099 O  O   . HOH H 4 .   ? 47.919  7.386   -11.142 1 31.919 ? 869  HOH B O   1 
HETATM 9100 O  O   . HOH H 4 .   ? 22.169  -21.853 14.202  1 19.028 ? 870  HOH B O   1 
HETATM 9101 O  O   . HOH H 4 .   ? 39.906  13.417  10.675  1 26.556 ? 871  HOH B O   1 
HETATM 9102 O  O   . HOH H 4 .   ? 42.084  5.663   -13.457 1 28.373 ? 872  HOH B O   1 
HETATM 9103 O  O   . HOH H 4 .   ? 28.062  20.028  0.568   1 21.404 ? 873  HOH B O   1 
HETATM 9104 O  O   . HOH H 4 .   ? 53.391  -2.391  3.846   1 26.527 ? 874  HOH B O   1 
HETATM 9105 O  O   . HOH H 4 .   ? -9.062  -22.003 43.133  1 20.992 ? 875  HOH B O   1 
HETATM 9106 O  O   . HOH H 4 .   ? 19.739  -17.01  4.395   1 23.218 ? 876  HOH B O   1 
HETATM 9107 O  O   . HOH H 4 .   ? 38.251  2.62    -12.893 1 25.477 ? 877  HOH B O   1 
HETATM 9108 O  O   . HOH H 4 .   ? 39.532  -4.494  13.391  1 12.99  ? 878  HOH B O   1 
HETATM 9109 O  O   . HOH H 4 .   ? 19.521  -3.313  11.241  1 13.94  ? 879  HOH B O   1 
HETATM 9110 O  O   . HOH H 4 .   ? 19.193  4.703   25.496  1 30.836 ? 880  HOH B O   1 
HETATM 9111 O  O   . HOH H 4 .   ? 18.849  -7.433  6.164   1 16.264 ? 881  HOH B O   1 
HETATM 9112 O  O   . HOH H 4 .   ? 35.556  -3.708  -17.463 1 30.199 ? 882  HOH B O   1 
HETATM 9113 O  O   . HOH H 4 .   ? -2.813  -9.343  21.472  1 22.242 ? 883  HOH B O   1 
HETATM 9114 O  O   . HOH H 4 .   ? 36.06   5.484   -8.762  1 27.368 ? 884  HOH B O   1 
HETATM 9115 O  O   . HOH H 4 .   ? 49.092  -11.029 -5.131  1 42.311 ? 885  HOH B O   1 
HETATM 9116 O  O   . HOH H 4 .   ? 0.958   -7.358  17.208  1 28.146 ? 886  HOH B O   1 
HETATM 9117 O  O   . HOH H 4 .   ? 42.917  3.015   3.226   1 28.396 ? 887  HOH B O   1 
HETATM 9118 O  O   . HOH H 4 .   ? 40.628  14.012  -5.985  1 39.126 ? 888  HOH B O   1 
HETATM 9119 O  O   . HOH H 4 .   ? 35.46   -19.351 28.071  1 15.689 ? 889  HOH B O   1 
HETATM 9120 O  O   . HOH H 4 .   ? 25.234  4.626   15.075  1 12.639 ? 890  HOH B O   1 
HETATM 9121 O  O   . HOH H 4 .   ? 29.511  15.969  9.017   1 19.352 ? 891  HOH B O   1 
HETATM 9122 O  O   . HOH H 4 .   ? 31.592  -9.033  30.251  1 21.677 ? 892  HOH B O   1 
HETATM 9123 O  O   . HOH H 4 .   ? 31.061  -1.177  23.497  1 12.082 ? 893  HOH B O   1 
HETATM 9124 O  O   . HOH H 4 .   ? 8.116   -15.81  18.078  1 13.375 ? 894  HOH B O   1 
HETATM 9125 O  O   . HOH H 4 .   ? 39.847  -13.509 18.463  1 25.624 ? 895  HOH B O   1 
HETATM 9126 O  O   . HOH H 4 .   ? 24.64   -21.689 29.012  1 36.081 ? 896  HOH B O   1 
HETATM 9127 O  O   . HOH H 4 .   ? 28.67   -11.442 24.249  1 15.03  ? 897  HOH B O   1 
HETATM 9128 O  O   . HOH H 4 .   ? 40.958  0.968   29.034  1 21.237 ? 898  HOH B O   1 
HETATM 9129 O  O   . HOH H 4 .   ? 33.424  -1.066  -23.467 1 42.263 ? 899  HOH B O   1 
HETATM 9130 O  O   . HOH H 4 .   ? 9.205   11.358  7.8     1 21.737 ? 900  HOH B O   1 
HETATM 9131 O  O   . HOH H 4 .   ? -0.235  -30.445 28.509  1 19.166 ? 901  HOH B O   1 
HETATM 9132 O  O   . HOH H 4 .   ? 45.436  4.742   17.736  1 16.484 ? 902  HOH B O   1 
HETATM 9133 O  O   . HOH H 4 .   ? 17.301  -13.396 -5.819  1 31.571 ? 903  HOH B O   1 
HETATM 9134 O  O   . HOH H 4 .   ? 25.159  -1.406  6.664   1 16.035 ? 904  HOH B O   1 
HETATM 9135 O  O   . HOH H 4 .   ? 36.403  -17.226 34.584  1 22.229 ? 905  HOH B O   1 
HETATM 9136 O  O   . HOH H 4 .   ? 28.033  -24.768 16.206  1 22.695 ? 906  HOH B O   1 
HETATM 9137 O  O   . HOH H 4 .   ? 23.739  2.255   -3.633  1 24.758 ? 907  HOH B O   1 
HETATM 9138 O  O   . HOH H 4 .   ? 33.183  3.901   25.507  1 17.273 ? 908  HOH B O   1 
HETATM 9139 O  O   . HOH H 4 .   ? 43.493  -12.828 22.986  1 21.326 ? 909  HOH B O   1 
HETATM 9140 O  O   . HOH H 4 .   ? 23.453  -26.286 14.574  1 36.393 ? 910  HOH B O   1 
HETATM 9141 O  O   . HOH H 4 .   ? 26.988  -9.542  6.165   1 35.074 ? 911  HOH B O   1 
HETATM 9142 O  O   . HOH H 4 .   ? 29.062  13.54   10.41   1 20.023 ? 912  HOH B O   1 
HETATM 9143 O  O   . HOH H 4 .   ? 52.891  0.089   5.673   1 29.503 ? 913  HOH B O   1 
HETATM 9144 O  O   . HOH H 4 .   ? 15.173  -4.016  -10.424 1 31.719 ? 914  HOH B O   1 
HETATM 9145 O  O   . HOH H 4 .   ? 2.771   -8.197  18.96   1 15.957 ? 915  HOH B O   1 
HETATM 9146 O  O   . HOH H 4 .   ? 21.474  5.822   15.203  1 16.093 ? 916  HOH B O   1 
HETATM 9147 O  O   . HOH H 4 .   ? 53.637  -4.78   13.362  1 23.902 ? 917  HOH B O   1 
HETATM 9148 O  O   . HOH H 4 .   ? 53.026  -5.919  1.827   1 39.881 ? 918  HOH B O   1 
HETATM 9149 O  O   . HOH H 4 .   ? 22.248  -2.686  33.273  1 13.759 ? 919  HOH B O   1 
HETATM 9150 O  O   . HOH H 4 .   ? 26.134  -6.25   -16.295 1 35.823 ? 920  HOH B O   1 
HETATM 9151 O  O   . HOH H 4 .   ? 39.659  -3.166  30.286  1 15.513 ? 921  HOH B O   1 
HETATM 9152 O  O   . HOH H 4 .   ? 52.335  -10.493 7.733   1 24.74  ? 922  HOH B O   1 
HETATM 9153 O  O   . HOH H 4 .   ? 22.548  4.057   23.664  1 26.782 ? 923  HOH B O   1 
HETATM 9154 O  O   . HOH H 4 .   ? 26.107  6.561   -12.091 1 49.281 ? 924  HOH B O   1 
HETATM 9155 O  O   . HOH H 4 .   ? 19.622  -2.003  18.254  1 15.464 ? 925  HOH B O   1 
HETATM 9156 O  O   . HOH H 4 .   ? 21.872  -8.627  26.68   1 14.128 ? 926  HOH B O   1 
HETATM 9157 O  O   . HOH H 4 .   ? 15.552  13.843  -2.376  1 37.062 ? 927  HOH B O   1 
HETATM 9158 O  O   . HOH H 4 .   ? 24.884  2.696   17.093  1 14.249 ? 928  HOH B O   1 
HETATM 9159 O  O   . HOH H 4 .   ? 31.806  0.524   25.655  1 18.098 ? 929  HOH B O   1 
HETATM 9160 O  O   . HOH H 4 .   ? 22.267  11.483  -6.68   1 37.46  ? 930  HOH B O   1 
HETATM 9161 O  O   . HOH H 4 .   ? 21.848  14.929  13.435  1 31.874 ? 931  HOH B O   1 
HETATM 9162 O  O   . HOH H 4 .   ? 47.687  3.793   21.642  1 15.833 ? 932  HOH B O   1 
HETATM 9163 O  O   . HOH H 4 .   ? 12.989  -18.035 27.663  1 33.195 ? 933  HOH B O   1 
HETATM 9164 O  O   . HOH H 4 .   ? 28.34   -11.14  32.576  1 14.021 ? 934  HOH B O   1 
HETATM 9165 O  O   . HOH H 4 .   ? 33.847  -6.309  30.854  1 18.054 ? 935  HOH B O   1 
HETATM 9166 O  O   . HOH H 4 .   ? 26.273  -25.993 7.805   1 34.865 ? 936  HOH B O   1 
HETATM 9167 O  O   . HOH H 4 .   ? 39.654  -0.27   23.138  1 17.796 ? 937  HOH B O   1 
HETATM 9168 O  O   . HOH H 4 .   ? 41.87   -8.686  -9.857  1 18.037 ? 938  HOH B O   1 
HETATM 9169 O  O   . HOH H 4 .   ? 29.731  13.773  17.848  1 29.107 ? 939  HOH B O   1 
HETATM 9170 O  O   . HOH H 4 .   ? 26.77   -13.072 -7.947  1 19.513 ? 940  HOH B O   1 
HETATM 9171 O  O   . HOH H 4 .   ? 37.001  5.301   23.37   1 34.342 ? 941  HOH B O   1 
HETATM 9172 O  O   . HOH H 4 .   ? 52.426  -9.945  12.87   1 17.269 ? 942  HOH B O   1 
HETATM 9173 O  O   . HOH H 4 .   ? 31.758  6.271   -10.104 1 20.73  ? 943  HOH B O   1 
HETATM 9174 O  O   . HOH H 4 .   ? 50.582  1.808   12.812  1 23.046 ? 944  HOH B O   1 
HETATM 9175 O  O   . HOH H 4 .   ? 51.957  -7.717  1.734   1 30.23  ? 945  HOH B O   1 
HETATM 9176 O  O   . HOH H 4 .   ? 26.531  0.706   18.758  1 16.447 ? 946  HOH B O   1 
HETATM 9177 O  O   . HOH H 4 .   ? 11.255  -11.832 3.636   1 23.974 ? 947  HOH B O   1 
HETATM 9178 O  O   . HOH H 4 .   ? 30.373  13.708  -7.901  1 22     ? 948  HOH B O   1 
HETATM 9179 O  O   . HOH H 4 .   ? 47.18   8.582   -3.783  1 34.644 ? 949  HOH B O   1 
HETATM 9180 O  O   . HOH H 4 .   ? 51.081  -12.25  19.028  1 14.622 ? 950  HOH B O   1 
HETATM 9181 O  O   . HOH H 4 .   ? 42.803  -1.141  35.715  1 21.848 ? 951  HOH B O   1 
HETATM 9182 O  O   . HOH H 4 .   ? 18.715  -3.797  -10.233 1 27.04  ? 952  HOH B O   1 
HETATM 9183 O  O   . HOH H 4 .   ? 4.755   11.563  6.402   1 45.411 ? 953  HOH B O   1 
HETATM 9184 O  O   . HOH H 4 .   ? 3.718   -19.949 15.279  1 31.925 ? 954  HOH B O   1 
HETATM 9185 O  O   . HOH H 4 .   ? 50.263  -15.571 0.338   1 32.179 ? 955  HOH B O   1 
HETATM 9186 O  O   . HOH H 4 .   ? 37.892  -22.724 -7.572  1 35.629 ? 956  HOH B O   1 
HETATM 9187 O  O   . HOH H 4 .   ? 27.38   -4.049  37.463  1 23.063 ? 957  HOH B O   1 
HETATM 9188 O  O   . HOH H 4 .   ? 52.936  -9.908  -0.943  1 40.345 ? 958  HOH B O   1 
HETATM 9189 O  O   . HOH H 4 .   ? 36.256  -1.685  5.069   1 12.83  ? 959  HOH B O   1 
HETATM 9190 O  O   . HOH H 4 .   ? 36.044  -6.022  21.731  1 13.66  ? 960  HOH B O   1 
HETATM 9191 O  O   . HOH H 4 .   ? 36.721  -8.314  20.568  1 13.638 ? 961  HOH B O   1 
HETATM 9192 O  O   . HOH H 4 .   ? 21.089  -14.011 6.219   1 18.47  ? 962  HOH B O   1 
HETATM 9193 O  O   . HOH H 4 .   ? 17.117  -14.872 25.968  1 15.873 ? 963  HOH B O   1 
HETATM 9194 O  O   . HOH H 4 .   ? 32.766  -7.056  37.297  1 14.268 ? 964  HOH B O   1 
HETATM 9195 O  O   . HOH H 4 .   ? 37.622  -4.873  27.734  1 12.487 ? 965  HOH B O   1 
HETATM 9196 O  O   . HOH H 4 .   ? 22.761  3.934   13.595  1 13.222 ? 966  HOH B O   1 
HETATM 9197 O  O   . HOH H 4 .   ? 31.669  12.848  9.675   1 16.014 ? 967  HOH B O   1 
HETATM 9198 O  O   . HOH H 4 .   ? 12.341  -26.075 8.838   1 34.198 ? 968  HOH B O   1 
HETATM 9199 O  O   . HOH H 4 .   ? 48.99   -20.086 14.947  1 37.133 ? 969  HOH B O   1 
HETATM 9200 O  O   . HOH H 4 .   ? 44.28   -10.111 15.032  1 13.92  ? 970  HOH B O   1 
HETATM 9201 O  O   . HOH H 4 .   ? 45.368  11.313  -0.071  1 30.394 ? 971  HOH B O   1 
HETATM 9202 O  O   . HOH H 4 .   ? 21.73   -5.495  2.431   1 21.682 ? 972  HOH B O   1 
HETATM 9203 O  O   . HOH H 4 .   ? 49.669  -18.091 26.542  1 31.945 ? 973  HOH B O   1 
HETATM 9204 O  O   . HOH H 4 .   ? 25.394  -22.572 25.439  1 18.534 ? 974  HOH B O   1 
HETATM 9205 O  O   . HOH H 4 .   ? 39.475  -6.991  21.967  1 12.853 ? 975  HOH B O   1 
HETATM 9206 O  O   . HOH H 4 .   ? 1.198   2.91    23.62   1 43.569 ? 976  HOH B O   1 
HETATM 9207 O  O   . HOH H 4 .   ? 39.366  -19.698 -5.387  1 16.218 ? 977  HOH B O   1 
HETATM 9208 O  O   . HOH H 4 .   ? 14.652  1.276   29.606  1 16.559 ? 978  HOH B O   1 
HETATM 9209 O  O   . HOH H 4 .   ? 52.995  -2.588  27.584  1 33.183 ? 979  HOH B O   1 
HETATM 9210 O  O   . HOH H 4 .   ? 28.248  -6.291  -1.7    1 15.467 ? 980  HOH B O   1 
HETATM 9211 O  O   . HOH H 4 .   ? 52.605  5.144   6.094   1 31.946 ? 981  HOH B O   1 
HETATM 9212 O  O   . HOH H 4 .   ? 49.285  -19.373 3.597   1 42.669 ? 982  HOH B O   1 
HETATM 9213 O  O   . HOH H 4 .   ? 23.647  -19.647 25.374  1 23.99  ? 983  HOH B O   1 
HETATM 9214 O  O   . HOH H 4 .   ? 26.242  0.706   -6.895  1 24.541 ? 984  HOH B O   1 
HETATM 9215 O  O   . HOH H 4 .   ? 36.657  3.393   -17.164 1 30.894 ? 985  HOH B O   1 
HETATM 9216 O  O   . HOH H 4 .   ? 27.244  -7.187  5.057   1 19.128 ? 986  HOH B O   1 
HETATM 9217 O  O   . HOH H 4 .   ? 29.094  -1.648  25.804  1 21.25  ? 987  HOH B O   1 
HETATM 9218 O  O   . HOH H 4 .   ? 51.104  9.196   12.364  1 32.964 ? 988  HOH B O   1 
HETATM 9219 O  O   . HOH H 4 .   ? 11.022  -19.294 26.183  1 28.879 ? 989  HOH B O   1 
HETATM 9220 O  O   . HOH H 4 .   ? -0.869  -6.075  13.93   1 26.208 ? 990  HOH B O   1 
HETATM 9221 O  O   . HOH H 4 .   ? 13.687  -20.911 0.258   1 48.254 ? 991  HOH B O   1 
HETATM 9222 O  O   . HOH H 4 .   ? 40.808  -9.183  36.148  1 27.907 ? 992  HOH B O   1 
HETATM 9223 O  O   . HOH H 4 .   ? 15.178  20.435  3.187   1 45.139 ? 993  HOH B O   1 
HETATM 9224 O  O   . HOH H 4 .   ? 8.61    -11.217 5.413   1 13.168 ? 994  HOH B O   1 
HETATM 9225 O  O   . HOH H 4 .   ? 7.808   -22.279 20.365  1 26.503 ? 995  HOH B O   1 
HETATM 9226 O  O   . HOH H 4 .   ? -20.492 -20.665 41.488  1 14.437 ? 996  HOH B O   1 
HETATM 9227 O  O   . HOH H 4 .   ? 12.385  -5.087  -9.937  1 30.52  ? 997  HOH B O   1 
HETATM 9228 O  O   . HOH H 4 .   ? 3.176   -11.33  27.361  1 15.175 ? 998  HOH B O   1 
HETATM 9229 O  O   . HOH H 4 .   ? 30.049  -3.214  11.845  1 12.979 ? 999  HOH B O   1 
HETATM 9230 O  O   . HOH H 4 .   ? 48.412  -18.292 -4.921  1 22.415 ? 1000 HOH B O   1 
HETATM 9231 O  O   . HOH H 4 .   ? 19.628  -26.187 19.396  1 32.514 ? 1001 HOH B O   1 
HETATM 9232 O  O   . HOH H 4 .   ? 0.511   -6.557  22.935  1 19.089 ? 1002 HOH B O   1 
HETATM 9233 O  O   . HOH H 4 .   ? 12.531  -20.3   22.013  1 26.176 ? 1003 HOH B O   1 
HETATM 9234 O  O   . HOH H 4 .   ? 16.457  -10.645 3.654   1 20.092 ? 1004 HOH B O   1 
HETATM 9235 O  O   . HOH H 4 .   ? 48.901  -11.416 -2.068  1 23.511 ? 1005 HOH B O   1 
HETATM 9236 O  O   . HOH H 4 .   ? 24.139  -8.145  -12.825 1 20.725 ? 1006 HOH B O   1 
HETATM 9237 O  O   . HOH H 4 .   ? 39.854  -25.332 2.38    1 22.43  ? 1007 HOH B O   1 
HETATM 9238 O  O   . HOH H 4 .   ? 18.132  1.109   20.752  1 24.777 ? 1008 HOH B O   1 
HETATM 9239 O  O   . HOH H 4 .   ? 47.015  0.534   -6.852  1 28.154 ? 1009 HOH B O   1 
HETATM 9240 O  O   . HOH H 4 .   ? 39.971  -4.304  37.282  1 39.86  ? 1010 HOH B O   1 
HETATM 9241 O  O   . HOH H 4 .   ? 21.952  -20.622 3.026   1 20.551 ? 1011 HOH B O   1 
HETATM 9242 O  O   . HOH H 4 .   ? 38.411  -10.538 9.253   1 12.919 ? 1012 HOH B O   1 
HETATM 9243 O  O   . HOH H 4 .   ? 24.924  -29.942 4.485   1 35.334 ? 1013 HOH B O   1 
HETATM 9244 O  O   . HOH H 4 .   ? 47.679  1.35    -1.767  1 17.225 ? 1014 HOH B O   1 
HETATM 9245 O  O   . HOH H 4 .   ? 42.707  -0.286  17.73   1 15.653 ? 1015 HOH B O   1 
HETATM 9246 O  O   . HOH H 4 .   ? 16.986  -7.279  1.807   1 20.868 ? 1016 HOH B O   1 
HETATM 9247 O  O   . HOH H 4 .   ? 22.606  4.983   26.425  1 27.381 ? 1017 HOH B O   1 
HETATM 9248 O  O   . HOH H 4 .   ? 6.72    -25.193 28.133  1 39.177 ? 1018 HOH B O   1 
HETATM 9249 O  O   . HOH H 4 .   ? 39.098  11.814  -10.918 1 27.134 ? 1019 HOH B O   1 
HETATM 9250 O  O   . HOH H 4 .   ? 2.232   -18.269 10.153  1 44.782 ? 1020 HOH B O   1 
HETATM 9251 O  O   . HOH H 4 .   ? 25.17   -25.498 23.214  1 21.371 ? 1021 HOH B O   1 
HETATM 9252 O  O   . HOH H 4 .   ? 33.41   -18.014 10.799  1 14.834 ? 1022 HOH B O   1 
HETATM 9253 O  O   . HOH H 4 .   ? 3.289   -11.7   1.294   1 29.479 ? 1023 HOH B O   1 
HETATM 9254 O  O   . HOH H 4 .   ? 32.686  -24.896 19.235  1 28.676 ? 1024 HOH B O   1 
HETATM 9255 O  O   . HOH H 4 .   ? 51.381  -11.883 15.898  1 16.753 ? 1025 HOH B O   1 
HETATM 9256 O  O   . HOH H 4 .   ? 45.568  -8.744  6.932   1 16.554 ? 1026 HOH B O   1 
HETATM 9257 O  O   . HOH H 4 .   ? 34.254  7.308   -10.625 1 21.772 ? 1027 HOH B O   1 
HETATM 9258 O  O   . HOH H 4 .   ? 22.508  -7.244  4.263   1 29.322 ? 1028 HOH B O   1 
HETATM 9259 O  O   . HOH H 4 .   ? 45.914  -1.434  33.982  1 14.705 ? 1029 HOH B O   1 
HETATM 9260 O  O   . HOH H 4 .   ? 45.755  -20.313 -1.585  1 23.135 ? 1030 HOH B O   1 
HETATM 9261 O  O   . HOH H 4 .   ? 33.274  -13.421 12.506  1 9.792  ? 1031 HOH B O   1 
HETATM 9262 O  O   . HOH H 4 .   ? 55.519  12.307  16.564  1 37.453 ? 1032 HOH B O   1 
HETATM 9263 O  O   . HOH H 4 .   ? 21.928  2.276   -5.73   1 31.411 ? 1033 HOH B O   1 
HETATM 9264 O  O   . HOH H 4 .   ? 5.376   -7.867  -8.16   1 44.047 ? 1034 HOH B O   1 
HETATM 9265 O  O   . HOH H 4 .   ? 21.879  19.445  6.029   1 32.798 ? 1035 HOH B O   1 
HETATM 9266 O  O   . HOH H 4 .   ? 29.576  -14.676 -13.683 1 35.742 ? 1036 HOH B O   1 
HETATM 9267 O  O   . HOH H 4 .   ? 20.546  10.67   37.737  1 36.866 ? 1037 HOH B O   1 
HETATM 9268 O  O   . HOH H 4 .   ? 25.213  2.336   -17.55  1 41.806 ? 1038 HOH B O   1 
HETATM 9269 O  O   . HOH H 4 .   ? 44.911  -6.252  6.202   1 16.441 ? 1039 HOH B O   1 
HETATM 9270 O  O   . HOH H 4 .   ? 34.65   11.957  13.727  1 25.546 ? 1040 HOH B O   1 
HETATM 9271 O  O   . HOH H 4 .   ? 44.62   -18.082 27.202  1 37.244 ? 1041 HOH B O   1 
HETATM 9272 O  O   . HOH H 4 .   ? 11.04   -22.522 7.709   1 19.975 ? 1042 HOH B O   1 
HETATM 9273 O  O   . HOH H 4 .   ? -22.786 -29.031 42.497  1 40.205 ? 1043 HOH B O   1 
HETATM 9274 O  O   . HOH H 4 .   ? 11.557  -23.393 3.373   1 36.996 ? 1044 HOH B O   1 
HETATM 9275 O  O   . HOH H 4 .   ? 5.147   8.343   10.616  1 21.108 ? 1045 HOH B O   1 
HETATM 9276 O  O   . HOH H 4 .   ? 5.855   -4.38   24.841  1 20.797 ? 1046 HOH B O   1 
HETATM 9277 O  O   . HOH H 4 .   ? 18.618  -14.866 -8.189  1 37.427 ? 1047 HOH B O   1 
HETATM 9278 O  O   . HOH H 4 .   ? 30.247  -26.843 19.451  1 33.885 ? 1048 HOH B O   1 
HETATM 9279 O  O   . HOH H 4 .   ? 30.193  7.621   40.65   1 30.576 ? 1049 HOH B O   1 
HETATM 9280 O  O   . HOH H 4 .   ? -4.479  -24.244 28.871  1 19.83  ? 1050 HOH B O   1 
HETATM 9281 O  O   . HOH H 4 .   ? -6.279  -29.938 31.639  1 17.612 ? 1051 HOH B O   1 
HETATM 9282 O  O   . HOH H 4 .   ? 50.452  -19.461 -8.19   1 33.749 ? 1052 HOH B O   1 
HETATM 9283 O  O   . HOH H 4 .   ? -24.572 -23.945 34.465  1 34.069 ? 1053 HOH B O   1 
HETATM 9284 O  O   . HOH H 4 .   ? 33.83   20.176  14.214  1 30.93  ? 1054 HOH B O   1 
HETATM 9285 O  O   . HOH H 4 .   ? 10.829  11.723  0.461   1 21.835 ? 1055 HOH B O   1 
HETATM 9286 O  O   . HOH H 4 .   ? 4.62    7.982   -2.23   1 37.604 ? 1056 HOH B O   1 
HETATM 9287 O  O   . HOH H 4 .   ? 47.914  7.486   -16.691 1 39.201 ? 1057 HOH B O   1 
HETATM 9288 O  O   . HOH H 4 .   ? 30.452  -11.507 30.969  1 13.842 ? 1058 HOH B O   1 
HETATM 9289 O  O   . HOH H 4 .   ? 33.736  14.08   -2.873  1 31.003 ? 1059 HOH B O   1 
HETATM 9290 O  O   . HOH H 4 .   ? 48.229  -20.994 -5.932  1 34.361 ? 1060 HOH B O   1 
HETATM 9291 O  O   . HOH H 4 .   ? 22.508  18.165  18.049  1 34.504 ? 1061 HOH B O   1 
HETATM 9292 O  O   . HOH H 4 .   ? 11.783  -20.591 24.316  1 28.818 ? 1062 HOH B O   1 
HETATM 9293 O  O   . HOH H 4 .   ? 20.53   -25.359 27.631  1 42.096 ? 1063 HOH B O   1 
HETATM 9294 O  O   . HOH H 4 .   ? 29.78   -24.611 35.647  1 41.372 ? 1064 HOH B O   1 
HETATM 9295 O  O   . HOH H 4 .   ? 11.756  -9.468  -8.052  1 32.036 ? 1065 HOH B O   1 
HETATM 9296 O  O   . HOH H 4 .   ? 22.088  7.704   39.031  1 31.475 ? 1066 HOH B O   1 
HETATM 9297 O  O   . HOH H 4 .   ? 20.656  -3.909  24.974  1 15.401 ? 1067 HOH B O   1 
HETATM 9298 O  O   . HOH H 4 .   ? 24.249  -10.754 2.12    1 23.029 ? 1068 HOH B O   1 
HETATM 9299 O  O   . HOH H 4 .   ? 32.653  11.368  11.802  1 16.305 ? 1069 HOH B O   1 
HETATM 9300 O  O   . HOH H 4 .   ? 15.335  -24.292 19.539  1 24.246 ? 1070 HOH B O   1 
HETATM 9301 O  O   . HOH H 4 .   ? 9.428   -16.333 4.696   1 32.214 ? 1071 HOH B O   1 
HETATM 9302 O  O   . HOH H 4 .   ? 8.44    9.889   -0.497  1 44.991 ? 1072 HOH B O   1 
HETATM 9303 O  O   . HOH H 4 .   ? 32.181  3.634   43.332  1 46.304 ? 1073 HOH B O   1 
HETATM 9304 O  O   . HOH H 4 .   ? 56.119  -3.871  15.032  1 28.874 ? 1074 HOH B O   1 
HETATM 9305 O  O   . HOH H 4 .   ? 35.573  6.028   32.241  1 34.388 ? 1075 HOH B O   1 
HETATM 9306 O  O   . HOH H 4 .   ? 5.425   -13.803 16.579  1 19.732 ? 1076 HOH B O   1 
HETATM 9307 O  O   . HOH H 4 .   ? 25.431  -26.535 -2.083  1 35.711 ? 1077 HOH B O   1 
HETATM 9308 O  O   . HOH H 4 .   ? -6.661  -27.443 29.669  1 38.566 ? 1078 HOH B O   1 
HETATM 9309 O  O   . HOH H 4 .   ? 22.877  1.263   13.408  1 17.204 ? 1079 HOH B O   1 
HETATM 9310 O  O   . HOH H 4 .   ? 28.438  16.032  20.646  1 35.83  ? 1080 HOH B O   1 
HETATM 9311 O  O   . HOH H 4 .   ? -0.392  -4.37   21.332  1 21.895 ? 1081 HOH B O   1 
HETATM 9312 O  O   . HOH H 4 .   ? 41.597  -13.201 -13.119 1 39.246 ? 1082 HOH B O   1 
HETATM 9313 O  O   . HOH H 4 .   ? -1.171  -17.548 14.833  1 44.895 ? 1083 HOH B O   1 
HETATM 9314 O  O   . HOH H 4 .   ? 9.014   15.439  23.206  1 44.09  ? 1084 HOH B O   1 
HETATM 9315 O  O   . HOH H 4 .   ? 29.068  16.428  6.381   1 22.351 ? 1085 HOH B O   1 
HETATM 9316 O  O   . HOH H 4 .   ? 48.597  -5.251  -7.401  1 24.533 ? 1086 HOH B O   1 
HETATM 9317 O  O   . HOH H 4 .   ? -2.119  -14.21  14.633  1 45.807 ? 1087 HOH B O   1 
HETATM 9318 O  O   . HOH H 4 .   ? 16.05   5.577   24.566  1 29.331 ? 1088 HOH B O   1 
HETATM 9319 O  O   . HOH H 4 .   ? -15.212 -29.35  45.038  1 34.251 ? 1089 HOH B O   1 
HETATM 9320 O  O   . HOH H 4 .   ? -19.261 -22.621 44.643  1 25.46  ? 1090 HOH B O   1 
HETATM 9321 O  O   . HOH H 4 .   ? -10.947 -32.641 40.523  1 29.263 ? 1091 HOH B O   1 
HETATM 9322 O  O   . HOH H 4 .   ? 36.179  6.027   34.769  1 49.799 ? 1092 HOH B O   1 
HETATM 9323 O  O   . HOH H 4 .   ? 24.76   -5.986  5.866   1 18.736 ? 1093 HOH B O   1 
HETATM 9324 O  O   . HOH H 4 .   ? 22.149  -18.219 29.707  1 28.108 ? 1094 HOH B O   1 
HETATM 9325 O  O   . HOH H 4 .   ? 38.201  -23.206 15.194  1 18.985 ? 1095 HOH B O   1 
HETATM 9326 O  O   . HOH H 4 .   ? 36.118  -19.644 33.529  1 25.432 ? 1096 HOH B O   1 
HETATM 9327 O  O   . HOH H 4 .   ? 38.507  18.169  17.863  1 39.348 ? 1097 HOH B O   1 
HETATM 9328 O  O   . HOH H 4 .   ? 8.357   -11.872 0.385   1 35.898 ? 1098 HOH B O   1 
HETATM 9329 O  O   . HOH H 4 .   ? 53.132  1.164   11.894  1 27.554 ? 1099 HOH B O   1 
HETATM 9330 O  O   . HOH H 4 .   ? 22.338  14.638  -4.297  1 40.437 ? 1100 HOH B O   1 
HETATM 9331 O  O   . HOH H 4 .   ? 29.971  -28.953 10.968  1 49.709 ? 1101 HOH B O   1 
HETATM 9332 O  O   . HOH H 4 .   ? 39.003  -22.295 -5.155  1 24.671 ? 1102 HOH B O   1 
HETATM 9333 O  O   . HOH H 4 .   ? 35.516  11.504  -11.651 1 43.669 ? 1103 HOH B O   1 
HETATM 9334 O  O   . HOH H 4 .   ? -24.33  -21.352 36.103  1 30.388 ? 1104 HOH B O   1 
HETATM 9335 O  O   . HOH H 4 .   ? 9.097   -15.345 -0.396  1 36.105 ? 1105 HOH B O   1 
HETATM 9336 O  O   . HOH H 4 .   ? 24.13   17.784  8.316   1 30.186 ? 1106 HOH B O   1 
HETATM 9337 O  O   . HOH H 4 .   ? 6.148   -17.954 4.415   1 41.218 ? 1107 HOH B O   1 
HETATM 9338 O  O   . HOH H 4 .   ? 43.394  6.169   31.228  1 37.879 ? 1108 HOH B O   1 
HETATM 9339 O  O   . HOH H 4 .   ? 8.58    -9.149  -11.053 1 51.649 ? 1109 HOH B O   1 
HETATM 9340 O  O   . HOH H 4 .   ? 50.059  -2.948  29.374  1 33.789 ? 1110 HOH B O   1 
HETATM 9341 O  O   . HOH H 4 .   ? 49.718  3.941   11.671  1 25.747 ? 1111 HOH B O   1 
HETATM 9342 O  O   . HOH H 4 .   ? 23.86   4.284   -12.958 1 36.813 ? 1112 HOH B O   1 
HETATM 9343 O  O   . HOH H 4 .   ? 30.272  -17.125 -9.269  1 35.25  ? 1113 HOH B O   1 
HETATM 9344 O  O   . HOH H 4 .   ? 41.299  23.296  15.758  1 44.759 ? 1114 HOH B O   1 
HETATM 9345 O  O   . HOH H 4 .   ? 24.819  4.768   34.576  1 36.539 ? 1115 HOH B O   1 
HETATM 9346 O  O   . HOH H 4 .   ? -7.571  -25.335 28.312  1 30.483 ? 1116 HOH B O   1 
HETATM 9347 O  O   . HOH H 4 .   ? 21.766  -16.932 0.604   1 42.56  ? 1117 HOH B O   1 
HETATM 9348 O  O   . HOH H 4 .   ? 49.586  3.941   -14.279 1 41.746 ? 1118 HOH B O   1 
HETATM 9349 O  O   . HOH H 4 .   ? 17.864  3.588   32.685  1 24.941 ? 1119 HOH B O   1 
HETATM 9350 O  O   . HOH H 4 .   ? 39.528  -1.366  28.152  1 23.415 ? 1120 HOH B O   1 
HETATM 9351 O  O   . HOH H 4 .   ? 6.02    -1.92   -6.855  1 38.82  ? 1121 HOH B O   1 
HETATM 9352 O  O   . HOH H 4 .   ? 28.034  -28.869 14.32   1 44.491 ? 1122 HOH B O   1 
HETATM 9353 O  O   . HOH H 4 .   ? 26.203  -3.817  6.166   1 23.2   ? 1123 HOH B O   1 
HETATM 9354 O  O   . HOH H 4 .   ? 53.988  19.068  19.537  1 42.363 ? 1124 HOH B O   1 
HETATM 9355 O  O   . HOH H 4 .   ? 13.986  8.872   30.282  1 29.88  ? 1125 HOH B O   1 
HETATM 9356 O  O   . HOH H 4 .   ? 48.514  -21.419 5.325   1 48.728 ? 1126 HOH B O   1 
HETATM 9357 O  O   . HOH H 4 .   ? 26.415  4.138   -12.464 1 46.569 ? 1127 HOH B O   1 
HETATM 9358 O  O   . HOH H 4 .   ? 19.382  18.727  14.501  1 29.924 ? 1128 HOH B O   1 
HETATM 9359 O  O   . HOH H 4 .   ? 32.391  -16.788 -10.473 1 46.142 ? 1129 HOH B O   1 
HETATM 9360 O  O   . HOH H 4 .   ? 19.774  -16.142 1.961   1 30.367 ? 1130 HOH B O   1 
HETATM 9361 O  O   . HOH H 4 .   ? -0.065  -6.556  -3.084  1 35.247 ? 1131 HOH B O   1 
HETATM 9362 O  O   . HOH H 4 .   ? 15.806  -0.937  -15.293 1 57.842 ? 1132 HOH B O   1 
HETATM 9363 O  O   . HOH H 4 .   ? 50.105  -3.199  -7.069  1 36.334 ? 1133 HOH B O   1 
HETATM 9364 O  O   . HOH H 4 .   ? 28.14   11.575  -13.78  1 46.068 ? 1134 HOH B O   1 
HETATM 9365 O  O   . HOH H 4 .   ? 14.928  -1.35   -10.415 1 39.928 ? 1135 HOH B O   1 
HETATM 9366 O  O   . HOH H 4 .   ? 17.727  21.811  12.483  1 50.695 ? 1136 HOH B O   1 
HETATM 9367 O  O   . HOH H 4 .   ? 17.525  14.993  19.147  1 33.35  ? 1137 HOH B O   1 
HETATM 9368 O  O   . HOH H 4 .   ? 23.952  -10.067 4.738   1 46.574 ? 1138 HOH B O   1 
HETATM 9369 O  O   . HOH H 4 .   ? 42.299  -7.608  37.553  1 29.043 ? 1139 HOH B O   1 
HETATM 9370 O  O   . HOH H 4 .   ? 49.879  -18.052 -0.568  1 35.935 ? 1140 HOH B O   1 
HETATM 9371 O  O   . HOH H 4 .   ? 4.449   -20.133 4.974   1 50.232 ? 1141 HOH B O   1 
HETATM 9372 O  O   . HOH H 4 .   ? 19.669  -19.453 3.978   1 18.889 ? 1142 HOH B O   1 
HETATM 9373 O  O   . HOH H 4 .   ? 8.445   -22.825 28.592  1 45.855 ? 1143 HOH B O   1 
HETATM 9374 O  O   . HOH H 4 .   ? -2.061  -32.437 27.344  1 31.897 ? 1144 HOH B O   1 
HETATM 9375 O  O   . HOH H 4 .   ? 25.931  -25.973 25.856  1 33.28  ? 1145 HOH B O   1 
HETATM 9376 O  O   . HOH H 4 .   ? -2.942  2.006   12.286  1 29.866 ? 1146 HOH B O   1 
HETATM 9377 O  O   . HOH H 4 .   ? 4.626   10.649  9.458   1 36.58  ? 1147 HOH B O   1 
HETATM 9378 O  O   . HOH H 4 .   ? -7.477  -30.769 45.524  1 24.185 ? 1148 HOH B O   1 
HETATM 9379 O  O   . HOH H 4 .   ? 12.987  -23.781 20.619  1 33.33  ? 1149 HOH B O   1 
HETATM 9380 O  O   . HOH H 4 .   ? 15.281  -20.868 26.384  1 53.541 ? 1150 HOH B O   1 
HETATM 9381 O  O   . HOH H 4 .   ? 42.097  -8.164  40.201  1 39.184 ? 1151 HOH B O   1 
HETATM 9382 O  O   . HOH H 4 .   ? 47.787  8.066   20.854  1 36.523 ? 1152 HOH B O   1 
HETATM 9383 O  O   . HOH H 4 .   ? 46.448  10.202  21.455  1 49.664 ? 1153 HOH B O   1 
HETATM 9384 O  O   . HOH H 4 .   ? 41.023  -11.059 38.257  1 34.863 ? 1154 HOH B O   1 
HETATM 9385 O  O   . HOH H 4 .   ? 46.332  20.291  8.659   1 34.8   ? 1155 HOH B O   1 
HETATM 9386 O  O   . HOH H 4 .   ? 26.352  6.229   38.983  1 32.43  ? 1156 HOH B O   1 
HETATM 9387 O  O   . HOH H 4 .   ? 45.218  -7.95   -16.699 1 52.909 ? 1157 HOH B O   1 
HETATM 9388 O  O   . HOH H 4 .   ? 28.233  5.895   -13.372 1 33.615 ? 1158 HOH B O   1 
HETATM 9389 O  O   . HOH H 4 .   ? 28.021  4.842   33.434  1 35.043 ? 1159 HOH B O   1 
HETATM 9390 O  O   . HOH H 4 .   ? 24.601  8.396   -13.217 1 40.477 ? 1160 HOH B O   1 
HETATM 9391 O  O   . HOH H 4 .   ? 17.974  -24.07  25.212  1 30.828 ? 1161 HOH B O   1 
HETATM 9392 O  O   . HOH H 4 .   ? 47.254  -16.772 -12.718 1 40.154 ? 1162 HOH B O   1 
HETATM 9393 O  O   . HOH H 4 .   ? 8.829   21.629  19.057  1 49.649 ? 1163 HOH B O   1 
HETATM 9394 O  O   . HOH H 4 .   ? 53.483  -10.66  10.307  1 28.432 ? 1164 HOH B O   1 
HETATM 9395 O  O   . HOH H 4 .   ? 39.386  4.547   36.774  1 51.405 ? 1165 HOH B O   1 
HETATM 9396 O  O   . HOH H 4 .   ? 26.533  -14.033 -10.636 1 32.202 ? 1166 HOH B O   1 
HETATM 9397 O  O   . HOH H 4 .   ? 18.527  -14.758 5.329   1 28.815 ? 1167 HOH B O   1 
HETATM 9398 O  O   . HOH H 4 .   ? 17.63   -12.725 2.788   1 30.696 ? 1168 HOH B O   1 
HETATM 9399 O  O   . HOH H 4 .   ? 2.007   4.134   4.5     1 32.369 ? 1169 HOH B O   1 
HETATM 9400 O  O   . HOH H 4 .   ? 0.729   -11.172 0.259   1 43.651 ? 1170 HOH B O   1 
HETATM 9401 O  O   . HOH H 4 .   ? 18.221  12.401  36.847  1 43.812 ? 1171 HOH B O   1 
HETATM 9402 O  O   . HOH H 4 .   ? 53.882  -11.843 14.549  1 17.861 ? 1172 HOH B O   1 
HETATM 9403 O  O   . HOH H 4 .   ? 40.924  3.285   -12.998 1 22.28  ? 1173 HOH B O   1 
HETATM 9404 O  O   . HOH H 4 .   ? 47.241  4.457   24.346  1 27.464 ? 1174 HOH B O   1 
HETATM 9405 O  O   . HOH H 4 .   ? 41.403  -23.433 -5.983  1 20.774 ? 1175 HOH B O   1 
HETATM 9406 O  O   . HOH H 4 .   ? 18.206  -24.517 13.962  1 23.312 ? 1176 HOH B O   1 
HETATM 9407 O  O   . HOH H 4 .   ? 47.024  10.794  -2.100  1 43.32  ? 1177 HOH B O   1 
HETATM 9408 O  O   . HOH H 4 .   ? 21.529  13.746  20.711  1 40.233 ? 1178 HOH B O   1 
HETATM 9409 O  O   . HOH H 4 .   ? 54.388  -7.787  12.761  1 23.549 ? 1179 HOH B O   1 
HETATM 9410 O  O   . HOH H 4 .   ? 37.307  4.244   -14.875 1 23.67  ? 1180 HOH B O   1 
HETATM 9411 O  O   . HOH H 4 .   ? 39.703  -25.613 4.665   1 22.271 ? 1181 HOH B O   1 
HETATM 9412 O  O   . HOH H 4 .   ? 19.872  23.387  42.945  1 40.3   ? 1182 HOH B O   1 
HETATM 9413 O  O   . HOH H 4 .   ? 47.568  14.816  21.029  1 60.11  ? 1183 HOH B O   1 
HETATM 9414 O  O   . HOH H 4 .   ? 16.683  20.132  -0.642  1 45.201 ? 1184 HOH B O   1 
HETATM 9415 O  O   . HOH H 4 .   ? 15.21   -24.369 25.353  1 37.13  ? 1185 HOH B O   1 
HETATM 9416 O  O   . HOH H 4 .   ? 18.471  -27.06  12.552  1 31.838 ? 1186 HOH B O   1 
HETATM 9417 O  O   . HOH H 4 .   ? 14.479  -13.281 -6.118  1 32.672 ? 1187 HOH B O   1 
HETATM 9418 O  O   . HOH H 4 .   ? 26.826  17.891  5.522   1 31.284 ? 1188 HOH B O   1 
HETATM 9419 O  O   . HOH H 4 .   ? 43.275  -17.043 36.047  1 35.487 ? 1189 HOH B O   1 
HETATM 9420 O  O   . HOH H 4 .   ? -6.186  -32.654 31.1    1 42.217 ? 1190 HOH B O   1 
HETATM 9421 O  O   . HOH H 4 .   ? 30.69   9.839   26.813  1 40.218 ? 1191 HOH B O   1 
HETATM 9422 O  O   . HOH H 4 .   ? 6.66    -16.646 15.746  1 20.58  ? 1192 HOH B O   1 
HETATM 9423 O  O   . HOH H 4 .   ? 0.986   -8.652  -2.238  1 39.921 ? 1193 HOH B O   1 
HETATM 9424 O  O   . HOH H 4 .   ? 2.15    -35.818 31.975  1 53.404 ? 1194 HOH B O   1 
HETATM 9425 O  O   . HOH H 4 .   ? 21.271  -26.798 15.973  1 28.619 ? 1195 HOH B O   1 
HETATM 9426 O  O   . HOH H 4 .   ? 16.993  -23.112 2.422   1 44.718 ? 1196 HOH B O   1 
HETATM 9427 O  O   . HOH H 4 .   ? 42.597  11.789  21.452  1 40.411 ? 1197 HOH B O   1 
HETATM 9428 O  O   . HOH H 4 .   ? 44.759  11.916  19.781  1 40.914 ? 1198 HOH B O   1 
HETATM 9429 O  O   . HOH H 4 .   ? 47.268  -23.822 5.427   1 38.3   ? 1199 HOH B O   1 
HETATM 9430 O  O   . HOH H 4 .   ? -27.599 -19.711 46.98   1 33.459 ? 1200 HOH B O   1 
HETATM 9431 O  O   . HOH H 4 .   ? 13.171  -28.773 8.154   1 57.439 ? 1201 HOH B O   1 
HETATM 9432 O  O   . HOH H 4 .   ? 50.769  4.433   21.642  1 26.648 ? 1202 HOH B O   1 
HETATM 9433 O  O   . HOH H 4 .   ? 8.448   -26.944 27.725  1 39.618 ? 1203 HOH B O   1 
HETATM 9434 O  O   . HOH H 4 .   ? 49.68   3.037   -1.944  1 33.928 ? 1204 HOH B O   1 
HETATM 9435 O  O   . HOH H 4 .   ? 20.571  -16.797 -11.767 1 37.668 ? 1205 HOH B O   1 
HETATM 9436 O  O   . HOH H 4 .   ? 27.473  6.883   -16.706 1 49.255 ? 1206 HOH B O   1 
HETATM 9437 O  O   . HOH H 4 .   ? 16.101  -15.084 -8.446  1 37.457 ? 1207 HOH B O   1 
HETATM 9438 O  O   . HOH H 4 .   ? 24.848  -12.696 -12.999 1 38.812 ? 1208 HOH B O   1 
HETATM 9439 O  O   . HOH H 4 .   ? 18.003  -21.055 1.348   1 37.42  ? 1209 HOH B O   1 
HETATM 9440 O  O   . HOH H 4 .   ? 32.186  11.784  26.316  1 41.048 ? 1210 HOH B O   1 
# 
